data_9B7K
# 
_entry.id   9B7K 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9B7K         pdb_00009b7k 10.2210/pdb9b7k/pdb 
WWPDB D_1000282745 ?            ?                   
EMDB  EMD-44314    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-04-16 ? 
2 'EM metadata'     1 0 2025-04-16 ? 
3 'Half map'        1 0 2025-04-16 1 
4 'Half map'        1 0 2025-04-16 2 
5 Image             1 0 2025-04-16 ? 
6 'Primary map'     1 0 2025-04-16 ? 
7 'Structure model' 1 1 2025-05-28 ? 
8 'EM metadata'     1 1 2025-05-28 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Half map'        repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 Image             repository 'Initial release' ? ? 
6 6 'Primary map'     repository 'Initial release' ? ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 7 'Structure model' 'Data collection'      
2 8 'EM metadata'     'Data processing'      
3 8 'EM metadata'     'Experimental summary' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 7 'Structure model' em_admin    
2 7 'Structure model' em_software 
3 8 'EM metadata'     em_admin    
4 8 'EM metadata'     em_software 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 7 'Structure model' '_em_admin.last_update' 
2 7 'Structure model' '_em_software.name'     
3 8 'EM metadata'     '_em_admin.last_update' 
4 8 'EM metadata'     '_em_software.name'     
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9B7K 
_pdbx_database_status.recvd_initial_deposition_date   2024-03-27 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Fab2-1 in complex with the capsid of Adeno-associated virus type 9' 
_pdbx_database_related.db_id          EMD-44314 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              rmckenna@ufl.edu 
_pdbx_contact_author.name_first         Robert 
_pdbx_contact_author.name_last          McKenna 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-2792-935X 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Mietzsch, M.' 1 ? 
'McKenna, R.'  2 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Structural characterization of antibody-responses from Zolgensma treatment guides the design of a capsid suitable for redosing' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Mietzsch, M.'    1  ? 
primary 'Nelson, A.R.'    2  ? 
primary 'Hsi, J.'         3  ? 
primary 'Zachary, J.'     4  ? 
primary 'Potts, L.'       5  ? 
primary 'Chipman, P.'     6  ? 
primary 'Ghanem, M.'      7  ? 
primary 'Alexander, I.E.' 8  ? 
primary 'Logan, G.J.'     9  ? 
primary 'Huiskonen, J.'   10 ? 
primary 'McKenna, R.'     11 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Capsid protein VP1' 59873.875 6 ? ? ? ? 
2 polymer man 'Fab2-1 heavy chain' 14346.938 1 ? ? ? ? 
3 polymer man 'Fab2-1 light chain' 11521.570 1 ? ? ? ? 
4 water   nat water                18.015    1 ? ? ? ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MASGGGAPVADNNEGADGVGSSSGNWHCDSQWLGDRVITTSTRTWALPTYNNHLYKQISNSTSGGSSNDNAYFGYSTPWG
YFDFNRFHCHFSPRDWQRLINNNWGFRPKRLNFKLFNIQVKEVTDNNGVKTIANNLTSTVQVFTDSDYQLPYVLGSAHEG
CLPPFPADVFMIPQYGYLTLNDGSQAVGRSSFYCLEYFPSQMLRTGNNFQFSYEFENVPFHSSYAHSQSLDRLMNPLIDQ
YLYYLSKTINGSGQNQQTLKFSVAGPSNMAVQGRNYIPGPSYRQQRVSTTVTQNNNSEFAWPGASSWALNGRNSLMNPGP
AMASHKEGEDRFFPLSGSLIFGKQGTGRDNVDADKVMITNEEEIKTTNPVATESYGQVATNHQSAQAQAQTGWVQNQGIL
PGMVWQDRDVYLQGPIWAKIPHTDGNFHPSPLMGGFGMKHPPPQILIKNTPVPADPPTAFNKDKLNSFITQYSTGQVSVE
IEWELQKENSKRWNPEIQYTSNYYKSNNVEFAVNTEGVYSEPRPIGTRYLTRNL
;
;MASGGGAPVADNNEGADGVGSSSGNWHCDSQWLGDRVITTSTRTWALPTYNNHLYKQISNSTSGGSSNDNAYFGYSTPWG
YFDFNRFHCHFSPRDWQRLINNNWGFRPKRLNFKLFNIQVKEVTDNNGVKTIANNLTSTVQVFTDSDYQLPYVLGSAHEG
CLPPFPADVFMIPQYGYLTLNDGSQAVGRSSFYCLEYFPSQMLRTGNNFQFSYEFENVPFHSSYAHSQSLDRLMNPLIDQ
YLYYLSKTINGSGQNQQTLKFSVAGPSNMAVQGRNYIPGPSYRQQRVSTTVTQNNNSEFAWPGASSWALNGRNSLMNPGP
AMASHKEGEDRFFPLSGSLIFGKQGTGRDNVDADKVMITNEEEIKTTNPVATESYGQVATNHQSAQAQAQTGWVQNQGIL
PGMVWQDRDVYLQGPIWAKIPHTDGNFHPSPLMGGFGMKHPPPQILIKNTPVPADPPTAFNKDKLNSFITQYSTGQVSVE
IEWELQKENSKRWNPEIQYTSNYYKSNNVEFAVNTEGVYSEPRPIGTRYLTRNL
;
A,B,C,D,E,F ? 
2 'polypeptide(L)' no no 
;SEVQLLESGGGLVQPGKSLRLSCAASGFSFSNYAMSWVRQAPGKGLEWVSGISGSGGSTNYAESVRGRFTISRDNSKNTL
YLEMNSLRVEDTAVYYCAKGMSYYDRSGYFWAKYHYGMDVWGQGITVTVSS
;
;SEVQLLESGGGLVQPGKSLRLSCAASGFSFSNYAMSWVRQAPGKGLEWVSGISGSGGSTNYAESVRGRFTISRDNSKNTL
YLEMNSLRVEDTAVYYCAKGMSYYDRSGYFWAKYHYGMDVWGQGITVTVSS
;
H           ? 
3 'polypeptide(L)' no no 
;VLTQPPSASGTPGQRVTISCSGSSSNIGSNYVYWYQQIPGTAPKLLIYSNNQRPSGVPDRFSGSKSGTSASLAISGLRSE
DEADYYCAAWDDSLSGNWVFGGGTKLTVLG
;
;VLTQPPSASGTPGQRVTISCSGSSSNIGSNYVYWYQQIPGTAPKLLIYSNNQRPSGVPDRFSGSKSGTSASLAISGLRSE
DEADYYCAAWDDSLSGNWVFGGGTKLTVLG
;
L           ? 
# 
_pdbx_entity_nonpoly.entity_id   4 
_pdbx_entity_nonpoly.name        water 
_pdbx_entity_nonpoly.comp_id     HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ALA n 
1 3   SER n 
1 4   GLY n 
1 5   GLY n 
1 6   GLY n 
1 7   ALA n 
1 8   PRO n 
1 9   VAL n 
1 10  ALA n 
1 11  ASP n 
1 12  ASN n 
1 13  ASN n 
1 14  GLU n 
1 15  GLY n 
1 16  ALA n 
1 17  ASP n 
1 18  GLY n 
1 19  VAL n 
1 20  GLY n 
1 21  SER n 
1 22  SER n 
1 23  SER n 
1 24  GLY n 
1 25  ASN n 
1 26  TRP n 
1 27  HIS n 
1 28  CYS n 
1 29  ASP n 
1 30  SER n 
1 31  GLN n 
1 32  TRP n 
1 33  LEU n 
1 34  GLY n 
1 35  ASP n 
1 36  ARG n 
1 37  VAL n 
1 38  ILE n 
1 39  THR n 
1 40  THR n 
1 41  SER n 
1 42  THR n 
1 43  ARG n 
1 44  THR n 
1 45  TRP n 
1 46  ALA n 
1 47  LEU n 
1 48  PRO n 
1 49  THR n 
1 50  TYR n 
1 51  ASN n 
1 52  ASN n 
1 53  HIS n 
1 54  LEU n 
1 55  TYR n 
1 56  LYS n 
1 57  GLN n 
1 58  ILE n 
1 59  SER n 
1 60  ASN n 
1 61  SER n 
1 62  THR n 
1 63  SER n 
1 64  GLY n 
1 65  GLY n 
1 66  SER n 
1 67  SER n 
1 68  ASN n 
1 69  ASP n 
1 70  ASN n 
1 71  ALA n 
1 72  TYR n 
1 73  PHE n 
1 74  GLY n 
1 75  TYR n 
1 76  SER n 
1 77  THR n 
1 78  PRO n 
1 79  TRP n 
1 80  GLY n 
1 81  TYR n 
1 82  PHE n 
1 83  ASP n 
1 84  PHE n 
1 85  ASN n 
1 86  ARG n 
1 87  PHE n 
1 88  HIS n 
1 89  CYS n 
1 90  HIS n 
1 91  PHE n 
1 92  SER n 
1 93  PRO n 
1 94  ARG n 
1 95  ASP n 
1 96  TRP n 
1 97  GLN n 
1 98  ARG n 
1 99  LEU n 
1 100 ILE n 
1 101 ASN n 
1 102 ASN n 
1 103 ASN n 
1 104 TRP n 
1 105 GLY n 
1 106 PHE n 
1 107 ARG n 
1 108 PRO n 
1 109 LYS n 
1 110 ARG n 
1 111 LEU n 
1 112 ASN n 
1 113 PHE n 
1 114 LYS n 
1 115 LEU n 
1 116 PHE n 
1 117 ASN n 
1 118 ILE n 
1 119 GLN n 
1 120 VAL n 
1 121 LYS n 
1 122 GLU n 
1 123 VAL n 
1 124 THR n 
1 125 ASP n 
1 126 ASN n 
1 127 ASN n 
1 128 GLY n 
1 129 VAL n 
1 130 LYS n 
1 131 THR n 
1 132 ILE n 
1 133 ALA n 
1 134 ASN n 
1 135 ASN n 
1 136 LEU n 
1 137 THR n 
1 138 SER n 
1 139 THR n 
1 140 VAL n 
1 141 GLN n 
1 142 VAL n 
1 143 PHE n 
1 144 THR n 
1 145 ASP n 
1 146 SER n 
1 147 ASP n 
1 148 TYR n 
1 149 GLN n 
1 150 LEU n 
1 151 PRO n 
1 152 TYR n 
1 153 VAL n 
1 154 LEU n 
1 155 GLY n 
1 156 SER n 
1 157 ALA n 
1 158 HIS n 
1 159 GLU n 
1 160 GLY n 
1 161 CYS n 
1 162 LEU n 
1 163 PRO n 
1 164 PRO n 
1 165 PHE n 
1 166 PRO n 
1 167 ALA n 
1 168 ASP n 
1 169 VAL n 
1 170 PHE n 
1 171 MET n 
1 172 ILE n 
1 173 PRO n 
1 174 GLN n 
1 175 TYR n 
1 176 GLY n 
1 177 TYR n 
1 178 LEU n 
1 179 THR n 
1 180 LEU n 
1 181 ASN n 
1 182 ASP n 
1 183 GLY n 
1 184 SER n 
1 185 GLN n 
1 186 ALA n 
1 187 VAL n 
1 188 GLY n 
1 189 ARG n 
1 190 SER n 
1 191 SER n 
1 192 PHE n 
1 193 TYR n 
1 194 CYS n 
1 195 LEU n 
1 196 GLU n 
1 197 TYR n 
1 198 PHE n 
1 199 PRO n 
1 200 SER n 
1 201 GLN n 
1 202 MET n 
1 203 LEU n 
1 204 ARG n 
1 205 THR n 
1 206 GLY n 
1 207 ASN n 
1 208 ASN n 
1 209 PHE n 
1 210 GLN n 
1 211 PHE n 
1 212 SER n 
1 213 TYR n 
1 214 GLU n 
1 215 PHE n 
1 216 GLU n 
1 217 ASN n 
1 218 VAL n 
1 219 PRO n 
1 220 PHE n 
1 221 HIS n 
1 222 SER n 
1 223 SER n 
1 224 TYR n 
1 225 ALA n 
1 226 HIS n 
1 227 SER n 
1 228 GLN n 
1 229 SER n 
1 230 LEU n 
1 231 ASP n 
1 232 ARG n 
1 233 LEU n 
1 234 MET n 
1 235 ASN n 
1 236 PRO n 
1 237 LEU n 
1 238 ILE n 
1 239 ASP n 
1 240 GLN n 
1 241 TYR n 
1 242 LEU n 
1 243 TYR n 
1 244 TYR n 
1 245 LEU n 
1 246 SER n 
1 247 LYS n 
1 248 THR n 
1 249 ILE n 
1 250 ASN n 
1 251 GLY n 
1 252 SER n 
1 253 GLY n 
1 254 GLN n 
1 255 ASN n 
1 256 GLN n 
1 257 GLN n 
1 258 THR n 
1 259 LEU n 
1 260 LYS n 
1 261 PHE n 
1 262 SER n 
1 263 VAL n 
1 264 ALA n 
1 265 GLY n 
1 266 PRO n 
1 267 SER n 
1 268 ASN n 
1 269 MET n 
1 270 ALA n 
1 271 VAL n 
1 272 GLN n 
1 273 GLY n 
1 274 ARG n 
1 275 ASN n 
1 276 TYR n 
1 277 ILE n 
1 278 PRO n 
1 279 GLY n 
1 280 PRO n 
1 281 SER n 
1 282 TYR n 
1 283 ARG n 
1 284 GLN n 
1 285 GLN n 
1 286 ARG n 
1 287 VAL n 
1 288 SER n 
1 289 THR n 
1 290 THR n 
1 291 VAL n 
1 292 THR n 
1 293 GLN n 
1 294 ASN n 
1 295 ASN n 
1 296 ASN n 
1 297 SER n 
1 298 GLU n 
1 299 PHE n 
1 300 ALA n 
1 301 TRP n 
1 302 PRO n 
1 303 GLY n 
1 304 ALA n 
1 305 SER n 
1 306 SER n 
1 307 TRP n 
1 308 ALA n 
1 309 LEU n 
1 310 ASN n 
1 311 GLY n 
1 312 ARG n 
1 313 ASN n 
1 314 SER n 
1 315 LEU n 
1 316 MET n 
1 317 ASN n 
1 318 PRO n 
1 319 GLY n 
1 320 PRO n 
1 321 ALA n 
1 322 MET n 
1 323 ALA n 
1 324 SER n 
1 325 HIS n 
1 326 LYS n 
1 327 GLU n 
1 328 GLY n 
1 329 GLU n 
1 330 ASP n 
1 331 ARG n 
1 332 PHE n 
1 333 PHE n 
1 334 PRO n 
1 335 LEU n 
1 336 SER n 
1 337 GLY n 
1 338 SER n 
1 339 LEU n 
1 340 ILE n 
1 341 PHE n 
1 342 GLY n 
1 343 LYS n 
1 344 GLN n 
1 345 GLY n 
1 346 THR n 
1 347 GLY n 
1 348 ARG n 
1 349 ASP n 
1 350 ASN n 
1 351 VAL n 
1 352 ASP n 
1 353 ALA n 
1 354 ASP n 
1 355 LYS n 
1 356 VAL n 
1 357 MET n 
1 358 ILE n 
1 359 THR n 
1 360 ASN n 
1 361 GLU n 
1 362 GLU n 
1 363 GLU n 
1 364 ILE n 
1 365 LYS n 
1 366 THR n 
1 367 THR n 
1 368 ASN n 
1 369 PRO n 
1 370 VAL n 
1 371 ALA n 
1 372 THR n 
1 373 GLU n 
1 374 SER n 
1 375 TYR n 
1 376 GLY n 
1 377 GLN n 
1 378 VAL n 
1 379 ALA n 
1 380 THR n 
1 381 ASN n 
1 382 HIS n 
1 383 GLN n 
1 384 SER n 
1 385 ALA n 
1 386 GLN n 
1 387 ALA n 
1 388 GLN n 
1 389 ALA n 
1 390 GLN n 
1 391 THR n 
1 392 GLY n 
1 393 TRP n 
1 394 VAL n 
1 395 GLN n 
1 396 ASN n 
1 397 GLN n 
1 398 GLY n 
1 399 ILE n 
1 400 LEU n 
1 401 PRO n 
1 402 GLY n 
1 403 MET n 
1 404 VAL n 
1 405 TRP n 
1 406 GLN n 
1 407 ASP n 
1 408 ARG n 
1 409 ASP n 
1 410 VAL n 
1 411 TYR n 
1 412 LEU n 
1 413 GLN n 
1 414 GLY n 
1 415 PRO n 
1 416 ILE n 
1 417 TRP n 
1 418 ALA n 
1 419 LYS n 
1 420 ILE n 
1 421 PRO n 
1 422 HIS n 
1 423 THR n 
1 424 ASP n 
1 425 GLY n 
1 426 ASN n 
1 427 PHE n 
1 428 HIS n 
1 429 PRO n 
1 430 SER n 
1 431 PRO n 
1 432 LEU n 
1 433 MET n 
1 434 GLY n 
1 435 GLY n 
1 436 PHE n 
1 437 GLY n 
1 438 MET n 
1 439 LYS n 
1 440 HIS n 
1 441 PRO n 
1 442 PRO n 
1 443 PRO n 
1 444 GLN n 
1 445 ILE n 
1 446 LEU n 
1 447 ILE n 
1 448 LYS n 
1 449 ASN n 
1 450 THR n 
1 451 PRO n 
1 452 VAL n 
1 453 PRO n 
1 454 ALA n 
1 455 ASP n 
1 456 PRO n 
1 457 PRO n 
1 458 THR n 
1 459 ALA n 
1 460 PHE n 
1 461 ASN n 
1 462 LYS n 
1 463 ASP n 
1 464 LYS n 
1 465 LEU n 
1 466 ASN n 
1 467 SER n 
1 468 PHE n 
1 469 ILE n 
1 470 THR n 
1 471 GLN n 
1 472 TYR n 
1 473 SER n 
1 474 THR n 
1 475 GLY n 
1 476 GLN n 
1 477 VAL n 
1 478 SER n 
1 479 VAL n 
1 480 GLU n 
1 481 ILE n 
1 482 GLU n 
1 483 TRP n 
1 484 GLU n 
1 485 LEU n 
1 486 GLN n 
1 487 LYS n 
1 488 GLU n 
1 489 ASN n 
1 490 SER n 
1 491 LYS n 
1 492 ARG n 
1 493 TRP n 
1 494 ASN n 
1 495 PRO n 
1 496 GLU n 
1 497 ILE n 
1 498 GLN n 
1 499 TYR n 
1 500 THR n 
1 501 SER n 
1 502 ASN n 
1 503 TYR n 
1 504 TYR n 
1 505 LYS n 
1 506 SER n 
1 507 ASN n 
1 508 ASN n 
1 509 VAL n 
1 510 GLU n 
1 511 PHE n 
1 512 ALA n 
1 513 VAL n 
1 514 ASN n 
1 515 THR n 
1 516 GLU n 
1 517 GLY n 
1 518 VAL n 
1 519 TYR n 
1 520 SER n 
1 521 GLU n 
1 522 PRO n 
1 523 ARG n 
1 524 PRO n 
1 525 ILE n 
1 526 GLY n 
1 527 THR n 
1 528 ARG n 
1 529 TYR n 
1 530 LEU n 
1 531 THR n 
1 532 ARG n 
1 533 ASN n 
1 534 LEU n 
2 1   SER n 
2 2   GLU n 
2 3   VAL n 
2 4   GLN n 
2 5   LEU n 
2 6   LEU n 
2 7   GLU n 
2 8   SER n 
2 9   GLY n 
2 10  GLY n 
2 11  GLY n 
2 12  LEU n 
2 13  VAL n 
2 14  GLN n 
2 15  PRO n 
2 16  GLY n 
2 17  LYS n 
2 18  SER n 
2 19  LEU n 
2 20  ARG n 
2 21  LEU n 
2 22  SER n 
2 23  CYS n 
2 24  ALA n 
2 25  ALA n 
2 26  SER n 
2 27  GLY n 
2 28  PHE n 
2 29  SER n 
2 30  PHE n 
2 31  SER n 
2 32  ASN n 
2 33  TYR n 
2 34  ALA n 
2 35  MET n 
2 36  SER n 
2 37  TRP n 
2 38  VAL n 
2 39  ARG n 
2 40  GLN n 
2 41  ALA n 
2 42  PRO n 
2 43  GLY n 
2 44  LYS n 
2 45  GLY n 
2 46  LEU n 
2 47  GLU n 
2 48  TRP n 
2 49  VAL n 
2 50  SER n 
2 51  GLY n 
2 52  ILE n 
2 53  SER n 
2 54  GLY n 
2 55  SER n 
2 56  GLY n 
2 57  GLY n 
2 58  SER n 
2 59  THR n 
2 60  ASN n 
2 61  TYR n 
2 62  ALA n 
2 63  GLU n 
2 64  SER n 
2 65  VAL n 
2 66  ARG n 
2 67  GLY n 
2 68  ARG n 
2 69  PHE n 
2 70  THR n 
2 71  ILE n 
2 72  SER n 
2 73  ARG n 
2 74  ASP n 
2 75  ASN n 
2 76  SER n 
2 77  LYS n 
2 78  ASN n 
2 79  THR n 
2 80  LEU n 
2 81  TYR n 
2 82  LEU n 
2 83  GLU n 
2 84  MET n 
2 85  ASN n 
2 86  SER n 
2 87  LEU n 
2 88  ARG n 
2 89  VAL n 
2 90  GLU n 
2 91  ASP n 
2 92  THR n 
2 93  ALA n 
2 94  VAL n 
2 95  TYR n 
2 96  TYR n 
2 97  CYS n 
2 98  ALA n 
2 99  LYS n 
2 100 GLY n 
2 101 MET n 
2 102 SER n 
2 103 TYR n 
2 104 TYR n 
2 105 ASP n 
2 106 ARG n 
2 107 SER n 
2 108 GLY n 
2 109 TYR n 
2 110 PHE n 
2 111 TRP n 
2 112 ALA n 
2 113 LYS n 
2 114 TYR n 
2 115 HIS n 
2 116 TYR n 
2 117 GLY n 
2 118 MET n 
2 119 ASP n 
2 120 VAL n 
2 121 TRP n 
2 122 GLY n 
2 123 GLN n 
2 124 GLY n 
2 125 ILE n 
2 126 THR n 
2 127 VAL n 
2 128 THR n 
2 129 VAL n 
2 130 SER n 
2 131 SER n 
3 1   VAL n 
3 2   LEU n 
3 3   THR n 
3 4   GLN n 
3 5   PRO n 
3 6   PRO n 
3 7   SER n 
3 8   ALA n 
3 9   SER n 
3 10  GLY n 
3 11  THR n 
3 12  PRO n 
3 13  GLY n 
3 14  GLN n 
3 15  ARG n 
3 16  VAL n 
3 17  THR n 
3 18  ILE n 
3 19  SER n 
3 20  CYS n 
3 21  SER n 
3 22  GLY n 
3 23  SER n 
3 24  SER n 
3 25  SER n 
3 26  ASN n 
3 27  ILE n 
3 28  GLY n 
3 29  SER n 
3 30  ASN n 
3 31  TYR n 
3 32  VAL n 
3 33  TYR n 
3 34  TRP n 
3 35  TYR n 
3 36  GLN n 
3 37  GLN n 
3 38  ILE n 
3 39  PRO n 
3 40  GLY n 
3 41  THR n 
3 42  ALA n 
3 43  PRO n 
3 44  LYS n 
3 45  LEU n 
3 46  LEU n 
3 47  ILE n 
3 48  TYR n 
3 49  SER n 
3 50  ASN n 
3 51  ASN n 
3 52  GLN n 
3 53  ARG n 
3 54  PRO n 
3 55  SER n 
3 56  GLY n 
3 57  VAL n 
3 58  PRO n 
3 59  ASP n 
3 60  ARG n 
3 61  PHE n 
3 62  SER n 
3 63  GLY n 
3 64  SER n 
3 65  LYS n 
3 66  SER n 
3 67  GLY n 
3 68  THR n 
3 69  SER n 
3 70  ALA n 
3 71  SER n 
3 72  LEU n 
3 73  ALA n 
3 74  ILE n 
3 75  SER n 
3 76  GLY n 
3 77  LEU n 
3 78  ARG n 
3 79  SER n 
3 80  GLU n 
3 81  ASP n 
3 82  GLU n 
3 83  ALA n 
3 84  ASP n 
3 85  TYR n 
3 86  TYR n 
3 87  CYS n 
3 88  ALA n 
3 89  ALA n 
3 90  TRP n 
3 91  ASP n 
3 92  ASP n 
3 93  SER n 
3 94  LEU n 
3 95  SER n 
3 96  GLY n 
3 97  ASN n 
3 98  TRP n 
3 99  VAL n 
3 100 PHE n 
3 101 GLY n 
3 102 GLY n 
3 103 GLY n 
3 104 THR n 
3 105 LYS n 
3 106 LEU n 
3 107 THR n 
3 108 VAL n 
3 109 LEU n 
3 110 GLY n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 534 ?     ? cap ? AAV9 ? ? ? ? 'Adeno-associated virus' 272636 ? ? ? ? ? ? ? human 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK293 ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 131 human ? ?   ? ?    ? ? ? ? 'Homo sapiens'           9606   ? ? ? ? ? ? ? human 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK293 ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 110 human ? ?   ? ?    ? ? ? ? 'Homo sapiens'           9606   ? ? ? ? ? ? ? human 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? HEK293 ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   203 ?   ?   ?   A . n 
A 1 2   ALA 2   204 ?   ?   ?   A . n 
A 1 3   SER 3   205 ?   ?   ?   A . n 
A 1 4   GLY 4   206 ?   ?   ?   A . n 
A 1 5   GLY 5   207 ?   ?   ?   A . n 
A 1 6   GLY 6   208 ?   ?   ?   A . n 
A 1 7   ALA 7   209 ?   ?   ?   A . n 
A 1 8   PRO 8   210 ?   ?   ?   A . n 
A 1 9   VAL 9   211 ?   ?   ?   A . n 
A 1 10  ALA 10  212 ?   ?   ?   A . n 
A 1 11  ASP 11  213 ?   ?   ?   A . n 
A 1 12  ASN 12  214 ?   ?   ?   A . n 
A 1 13  ASN 13  215 ?   ?   ?   A . n 
A 1 14  GLU 14  216 ?   ?   ?   A . n 
A 1 15  GLY 15  217 ?   ?   ?   A . n 
A 1 16  ALA 16  218 ?   ?   ?   A . n 
A 1 17  ASP 17  219 ?   ?   ?   A . n 
A 1 18  GLY 18  220 220 GLY GLY A . n 
A 1 19  VAL 19  221 221 VAL VAL A . n 
A 1 20  GLY 20  222 222 GLY GLY A . n 
A 1 21  SER 21  223 223 SER SER A . n 
A 1 22  SER 22  224 224 SER SER A . n 
A 1 23  SER 23  225 225 SER SER A . n 
A 1 24  GLY 24  226 226 GLY GLY A . n 
A 1 25  ASN 25  227 227 ASN ASN A . n 
A 1 26  TRP 26  228 228 TRP TRP A . n 
A 1 27  HIS 27  229 229 HIS HIS A . n 
A 1 28  CYS 28  230 230 CYS CYS A . n 
A 1 29  ASP 29  231 231 ASP ASP A . n 
A 1 30  SER 30  232 232 SER SER A . n 
A 1 31  GLN 31  233 233 GLN GLN A . n 
A 1 32  TRP 32  234 234 TRP TRP A . n 
A 1 33  LEU 33  235 235 LEU LEU A . n 
A 1 34  GLY 34  236 236 GLY GLY A . n 
A 1 35  ASP 35  237 237 ASP ASP A . n 
A 1 36  ARG 36  238 238 ARG ARG A . n 
A 1 37  VAL 37  239 239 VAL VAL A . n 
A 1 38  ILE 38  240 240 ILE ILE A . n 
A 1 39  THR 39  241 241 THR THR A . n 
A 1 40  THR 40  242 242 THR THR A . n 
A 1 41  SER 41  243 243 SER SER A . n 
A 1 42  THR 42  244 244 THR THR A . n 
A 1 43  ARG 43  245 245 ARG ARG A . n 
A 1 44  THR 44  246 246 THR THR A . n 
A 1 45  TRP 45  247 247 TRP TRP A . n 
A 1 46  ALA 46  248 248 ALA ALA A . n 
A 1 47  LEU 47  249 249 LEU LEU A . n 
A 1 48  PRO 48  250 250 PRO PRO A . n 
A 1 49  THR 49  251 251 THR THR A . n 
A 1 50  TYR 50  252 252 TYR TYR A . n 
A 1 51  ASN 51  253 253 ASN ASN A . n 
A 1 52  ASN 52  254 254 ASN ASN A . n 
A 1 53  HIS 53  255 255 HIS HIS A . n 
A 1 54  LEU 54  256 256 LEU LEU A . n 
A 1 55  TYR 55  257 257 TYR TYR A . n 
A 1 56  LYS 56  258 258 LYS LYS A . n 
A 1 57  GLN 57  259 259 GLN GLN A . n 
A 1 58  ILE 58  260 260 ILE ILE A . n 
A 1 59  SER 59  261 261 SER SER A . n 
A 1 60  ASN 60  262 262 ASN ASN A . n 
A 1 61  SER 61  263 263 SER SER A . n 
A 1 62  THR 62  264 264 THR THR A . n 
A 1 63  SER 63  265 265 SER SER A . n 
A 1 64  GLY 64  266 266 GLY GLY A . n 
A 1 65  GLY 65  267 267 GLY GLY A . n 
A 1 66  SER 66  268 268 SER SER A . n 
A 1 67  SER 67  269 269 SER SER A . n 
A 1 68  ASN 68  270 270 ASN ASN A . n 
A 1 69  ASP 69  271 271 ASP ASP A . n 
A 1 70  ASN 70  272 272 ASN ASN A . n 
A 1 71  ALA 71  273 273 ALA ALA A . n 
A 1 72  TYR 72  274 274 TYR TYR A . n 
A 1 73  PHE 73  275 275 PHE PHE A . n 
A 1 74  GLY 74  276 276 GLY GLY A . n 
A 1 75  TYR 75  277 277 TYR TYR A . n 
A 1 76  SER 76  278 278 SER SER A . n 
A 1 77  THR 77  279 279 THR THR A . n 
A 1 78  PRO 78  280 280 PRO PRO A . n 
A 1 79  TRP 79  281 281 TRP TRP A . n 
A 1 80  GLY 80  282 282 GLY GLY A . n 
A 1 81  TYR 81  283 283 TYR TYR A . n 
A 1 82  PHE 82  284 284 PHE PHE A . n 
A 1 83  ASP 83  285 285 ASP ASP A . n 
A 1 84  PHE 84  286 286 PHE PHE A . n 
A 1 85  ASN 85  287 287 ASN ASN A . n 
A 1 86  ARG 86  288 288 ARG ARG A . n 
A 1 87  PHE 87  289 289 PHE PHE A . n 
A 1 88  HIS 88  290 290 HIS HIS A . n 
A 1 89  CYS 89  291 291 CYS CYS A . n 
A 1 90  HIS 90  292 292 HIS HIS A . n 
A 1 91  PHE 91  293 293 PHE PHE A . n 
A 1 92  SER 92  294 294 SER SER A . n 
A 1 93  PRO 93  295 295 PRO PRO A . n 
A 1 94  ARG 94  296 296 ARG ARG A . n 
A 1 95  ASP 95  297 297 ASP ASP A . n 
A 1 96  TRP 96  298 298 TRP TRP A . n 
A 1 97  GLN 97  299 299 GLN GLN A . n 
A 1 98  ARG 98  300 300 ARG ARG A . n 
A 1 99  LEU 99  301 301 LEU LEU A . n 
A 1 100 ILE 100 302 302 ILE ILE A . n 
A 1 101 ASN 101 303 303 ASN ASN A . n 
A 1 102 ASN 102 304 304 ASN ASN A . n 
A 1 103 ASN 103 305 305 ASN ASN A . n 
A 1 104 TRP 104 306 306 TRP TRP A . n 
A 1 105 GLY 105 307 307 GLY GLY A . n 
A 1 106 PHE 106 308 308 PHE PHE A . n 
A 1 107 ARG 107 309 309 ARG ARG A . n 
A 1 108 PRO 108 310 310 PRO PRO A . n 
A 1 109 LYS 109 311 311 LYS LYS A . n 
A 1 110 ARG 110 312 312 ARG ARG A . n 
A 1 111 LEU 111 313 313 LEU LEU A . n 
A 1 112 ASN 112 314 314 ASN ASN A . n 
A 1 113 PHE 113 315 315 PHE PHE A . n 
A 1 114 LYS 114 316 316 LYS LYS A . n 
A 1 115 LEU 115 317 317 LEU LEU A . n 
A 1 116 PHE 116 318 318 PHE PHE A . n 
A 1 117 ASN 117 319 319 ASN ASN A . n 
A 1 118 ILE 118 320 320 ILE ILE A . n 
A 1 119 GLN 119 321 321 GLN GLN A . n 
A 1 120 VAL 120 322 322 VAL VAL A . n 
A 1 121 LYS 121 323 323 LYS LYS A . n 
A 1 122 GLU 122 324 324 GLU GLU A . n 
A 1 123 VAL 123 325 325 VAL VAL A . n 
A 1 124 THR 124 326 326 THR THR A . n 
A 1 125 ASP 125 327 327 ASP ASP A . n 
A 1 126 ASN 126 328 328 ASN ASN A . n 
A 1 127 ASN 127 329 329 ASN ASN A . n 
A 1 128 GLY 128 330 330 GLY GLY A . n 
A 1 129 VAL 129 331 331 VAL VAL A . n 
A 1 130 LYS 130 332 332 LYS LYS A . n 
A 1 131 THR 131 333 333 THR THR A . n 
A 1 132 ILE 132 334 334 ILE ILE A . n 
A 1 133 ALA 133 335 335 ALA ALA A . n 
A 1 134 ASN 134 336 336 ASN ASN A . n 
A 1 135 ASN 135 337 337 ASN ASN A . n 
A 1 136 LEU 136 338 338 LEU LEU A . n 
A 1 137 THR 137 339 339 THR THR A . n 
A 1 138 SER 138 340 340 SER SER A . n 
A 1 139 THR 139 341 341 THR THR A . n 
A 1 140 VAL 140 342 342 VAL VAL A . n 
A 1 141 GLN 141 343 343 GLN GLN A . n 
A 1 142 VAL 142 344 344 VAL VAL A . n 
A 1 143 PHE 143 345 345 PHE PHE A . n 
A 1 144 THR 144 346 346 THR THR A . n 
A 1 145 ASP 145 347 347 ASP ASP A . n 
A 1 146 SER 146 348 348 SER SER A . n 
A 1 147 ASP 147 349 349 ASP ASP A . n 
A 1 148 TYR 148 350 350 TYR TYR A . n 
A 1 149 GLN 149 351 351 GLN GLN A . n 
A 1 150 LEU 150 352 352 LEU LEU A . n 
A 1 151 PRO 151 353 353 PRO PRO A . n 
A 1 152 TYR 152 354 354 TYR TYR A . n 
A 1 153 VAL 153 355 355 VAL VAL A . n 
A 1 154 LEU 154 356 356 LEU LEU A . n 
A 1 155 GLY 155 357 357 GLY GLY A . n 
A 1 156 SER 156 358 358 SER SER A . n 
A 1 157 ALA 157 359 359 ALA ALA A . n 
A 1 158 HIS 158 360 360 HIS HIS A . n 
A 1 159 GLU 159 361 361 GLU GLU A . n 
A 1 160 GLY 160 362 362 GLY GLY A . n 
A 1 161 CYS 161 363 363 CYS CYS A . n 
A 1 162 LEU 162 364 364 LEU LEU A . n 
A 1 163 PRO 163 365 365 PRO PRO A . n 
A 1 164 PRO 164 366 366 PRO PRO A . n 
A 1 165 PHE 165 367 367 PHE PHE A . n 
A 1 166 PRO 166 368 368 PRO PRO A . n 
A 1 167 ALA 167 369 369 ALA ALA A . n 
A 1 168 ASP 168 370 370 ASP ASP A . n 
A 1 169 VAL 169 371 371 VAL VAL A . n 
A 1 170 PHE 170 372 372 PHE PHE A . n 
A 1 171 MET 171 373 373 MET MET A . n 
A 1 172 ILE 172 374 374 ILE ILE A . n 
A 1 173 PRO 173 375 375 PRO PRO A . n 
A 1 174 GLN 174 376 376 GLN GLN A . n 
A 1 175 TYR 175 377 377 TYR TYR A . n 
A 1 176 GLY 176 378 378 GLY GLY A . n 
A 1 177 TYR 177 379 379 TYR TYR A . n 
A 1 178 LEU 178 380 380 LEU LEU A . n 
A 1 179 THR 179 381 381 THR THR A . n 
A 1 180 LEU 180 382 382 LEU LEU A . n 
A 1 181 ASN 181 383 383 ASN ASN A . n 
A 1 182 ASP 182 384 384 ASP ASP A . n 
A 1 183 GLY 183 385 385 GLY GLY A . n 
A 1 184 SER 184 386 386 SER SER A . n 
A 1 185 GLN 185 387 387 GLN GLN A . n 
A 1 186 ALA 186 388 388 ALA ALA A . n 
A 1 187 VAL 187 389 389 VAL VAL A . n 
A 1 188 GLY 188 390 390 GLY GLY A . n 
A 1 189 ARG 189 391 391 ARG ARG A . n 
A 1 190 SER 190 392 392 SER SER A . n 
A 1 191 SER 191 393 393 SER SER A . n 
A 1 192 PHE 192 394 394 PHE PHE A . n 
A 1 193 TYR 193 395 395 TYR TYR A . n 
A 1 194 CYS 194 396 396 CYS CYS A . n 
A 1 195 LEU 195 397 397 LEU LEU A . n 
A 1 196 GLU 196 398 398 GLU GLU A . n 
A 1 197 TYR 197 399 399 TYR TYR A . n 
A 1 198 PHE 198 400 400 PHE PHE A . n 
A 1 199 PRO 199 401 401 PRO PRO A . n 
A 1 200 SER 200 402 402 SER SER A . n 
A 1 201 GLN 201 403 403 GLN GLN A . n 
A 1 202 MET 202 404 404 MET MET A . n 
A 1 203 LEU 203 405 405 LEU LEU A . n 
A 1 204 ARG 204 406 406 ARG ARG A . n 
A 1 205 THR 205 407 407 THR THR A . n 
A 1 206 GLY 206 408 408 GLY GLY A . n 
A 1 207 ASN 207 409 409 ASN ASN A . n 
A 1 208 ASN 208 410 410 ASN ASN A . n 
A 1 209 PHE 209 411 411 PHE PHE A . n 
A 1 210 GLN 210 412 412 GLN GLN A . n 
A 1 211 PHE 211 413 413 PHE PHE A . n 
A 1 212 SER 212 414 414 SER SER A . n 
A 1 213 TYR 213 415 415 TYR TYR A . n 
A 1 214 GLU 214 416 416 GLU GLU A . n 
A 1 215 PHE 215 417 417 PHE PHE A . n 
A 1 216 GLU 216 418 418 GLU GLU A . n 
A 1 217 ASN 217 419 419 ASN ASN A . n 
A 1 218 VAL 218 420 420 VAL VAL A . n 
A 1 219 PRO 219 421 421 PRO PRO A . n 
A 1 220 PHE 220 422 422 PHE PHE A . n 
A 1 221 HIS 221 423 423 HIS HIS A . n 
A 1 222 SER 222 424 424 SER SER A . n 
A 1 223 SER 223 425 425 SER SER A . n 
A 1 224 TYR 224 426 426 TYR TYR A . n 
A 1 225 ALA 225 427 427 ALA ALA A . n 
A 1 226 HIS 226 428 428 HIS HIS A . n 
A 1 227 SER 227 429 429 SER SER A . n 
A 1 228 GLN 228 430 430 GLN GLN A . n 
A 1 229 SER 229 431 431 SER SER A . n 
A 1 230 LEU 230 432 432 LEU LEU A . n 
A 1 231 ASP 231 433 433 ASP ASP A . n 
A 1 232 ARG 232 434 434 ARG ARG A . n 
A 1 233 LEU 233 435 435 LEU LEU A . n 
A 1 234 MET 234 436 436 MET MET A . n 
A 1 235 ASN 235 437 437 ASN ASN A . n 
A 1 236 PRO 236 438 438 PRO PRO A . n 
A 1 237 LEU 237 439 ?   ?   ?   A . n 
A 1 238 ILE 238 440 ?   ?   ?   A . n 
A 1 239 ASP 239 441 ?   ?   ?   A . n 
A 1 240 GLN 240 442 442 GLN GLN A . n 
A 1 241 TYR 241 443 443 TYR TYR A . n 
A 1 242 LEU 242 444 444 LEU LEU A . n 
A 1 243 TYR 243 445 445 TYR TYR A . n 
A 1 244 TYR 244 446 446 TYR TYR A . n 
A 1 245 LEU 245 447 447 LEU LEU A . n 
A 1 246 SER 246 448 448 SER SER A . n 
A 1 247 LYS 247 449 449 LYS LYS A . n 
A 1 248 THR 248 450 450 THR THR A . n 
A 1 249 ILE 249 451 451 ILE ILE A . n 
A 1 250 ASN 250 452 452 ASN ASN A . n 
A 1 251 GLY 251 453 453 GLY GLY A . n 
A 1 252 SER 252 454 454 SER SER A . n 
A 1 253 GLY 253 455 455 GLY GLY A . n 
A 1 254 GLN 254 456 456 GLN GLN A . n 
A 1 255 ASN 255 457 457 ASN ASN A . n 
A 1 256 GLN 256 458 458 GLN GLN A . n 
A 1 257 GLN 257 459 459 GLN GLN A . n 
A 1 258 THR 258 460 460 THR THR A . n 
A 1 259 LEU 259 461 461 LEU LEU A . n 
A 1 260 LYS 260 462 462 LYS LYS A . n 
A 1 261 PHE 261 463 463 PHE PHE A . n 
A 1 262 SER 262 464 464 SER SER A . n 
A 1 263 VAL 263 465 465 VAL VAL A . n 
A 1 264 ALA 264 466 466 ALA ALA A . n 
A 1 265 GLY 265 467 467 GLY GLY A . n 
A 1 266 PRO 266 468 468 PRO PRO A . n 
A 1 267 SER 267 469 469 SER SER A . n 
A 1 268 ASN 268 470 470 ASN ASN A . n 
A 1 269 MET 269 471 471 MET MET A . n 
A 1 270 ALA 270 472 472 ALA ALA A . n 
A 1 271 VAL 271 473 473 VAL VAL A . n 
A 1 272 GLN 272 474 474 GLN GLN A . n 
A 1 273 GLY 273 475 475 GLY GLY A . n 
A 1 274 ARG 274 476 476 ARG ARG A . n 
A 1 275 ASN 275 477 477 ASN ASN A . n 
A 1 276 TYR 276 478 478 TYR TYR A . n 
A 1 277 ILE 277 479 479 ILE ILE A . n 
A 1 278 PRO 278 480 480 PRO PRO A . n 
A 1 279 GLY 279 481 481 GLY GLY A . n 
A 1 280 PRO 280 482 482 PRO PRO A . n 
A 1 281 SER 281 483 483 SER SER A . n 
A 1 282 TYR 282 484 484 TYR TYR A . n 
A 1 283 ARG 283 485 485 ARG ARG A . n 
A 1 284 GLN 284 486 486 GLN GLN A . n 
A 1 285 GLN 285 487 487 GLN GLN A . n 
A 1 286 ARG 286 488 488 ARG ARG A . n 
A 1 287 VAL 287 489 489 VAL VAL A . n 
A 1 288 SER 288 490 490 SER SER A . n 
A 1 289 THR 289 491 491 THR THR A . n 
A 1 290 THR 290 492 492 THR THR A . n 
A 1 291 VAL 291 493 493 VAL VAL A . n 
A 1 292 THR 292 494 494 THR THR A . n 
A 1 293 GLN 293 495 495 GLN GLN A . n 
A 1 294 ASN 294 496 496 ASN ASN A . n 
A 1 295 ASN 295 497 497 ASN ASN A . n 
A 1 296 ASN 296 498 498 ASN ASN A . n 
A 1 297 SER 297 499 499 SER SER A . n 
A 1 298 GLU 298 500 500 GLU GLU A . n 
A 1 299 PHE 299 501 501 PHE PHE A . n 
A 1 300 ALA 300 502 502 ALA ALA A . n 
A 1 301 TRP 301 503 503 TRP TRP A . n 
A 1 302 PRO 302 504 504 PRO PRO A . n 
A 1 303 GLY 303 505 505 GLY GLY A . n 
A 1 304 ALA 304 506 506 ALA ALA A . n 
A 1 305 SER 305 507 507 SER SER A . n 
A 1 306 SER 306 508 508 SER SER A . n 
A 1 307 TRP 307 509 509 TRP TRP A . n 
A 1 308 ALA 308 510 510 ALA ALA A . n 
A 1 309 LEU 309 511 511 LEU LEU A . n 
A 1 310 ASN 310 512 512 ASN ASN A . n 
A 1 311 GLY 311 513 513 GLY GLY A . n 
A 1 312 ARG 312 514 514 ARG ARG A . n 
A 1 313 ASN 313 515 515 ASN ASN A . n 
A 1 314 SER 314 516 516 SER SER A . n 
A 1 315 LEU 315 517 517 LEU LEU A . n 
A 1 316 MET 316 518 518 MET MET A . n 
A 1 317 ASN 317 519 519 ASN ASN A . n 
A 1 318 PRO 318 520 520 PRO PRO A . n 
A 1 319 GLY 319 521 521 GLY GLY A . n 
A 1 320 PRO 320 522 522 PRO PRO A . n 
A 1 321 ALA 321 523 523 ALA ALA A . n 
A 1 322 MET 322 524 524 MET MET A . n 
A 1 323 ALA 323 525 525 ALA ALA A . n 
A 1 324 SER 324 526 526 SER SER A . n 
A 1 325 HIS 325 527 527 HIS HIS A . n 
A 1 326 LYS 326 528 528 LYS LYS A . n 
A 1 327 GLU 327 529 529 GLU GLU A . n 
A 1 328 GLY 328 530 530 GLY GLY A . n 
A 1 329 GLU 329 531 531 GLU GLU A . n 
A 1 330 ASP 330 532 532 ASP ASP A . n 
A 1 331 ARG 331 533 533 ARG ARG A . n 
A 1 332 PHE 332 534 534 PHE PHE A . n 
A 1 333 PHE 333 535 535 PHE PHE A . n 
A 1 334 PRO 334 536 536 PRO PRO A . n 
A 1 335 LEU 335 537 537 LEU LEU A . n 
A 1 336 SER 336 538 538 SER SER A . n 
A 1 337 GLY 337 539 539 GLY GLY A . n 
A 1 338 SER 338 540 540 SER SER A . n 
A 1 339 LEU 339 541 541 LEU LEU A . n 
A 1 340 ILE 340 542 542 ILE ILE A . n 
A 1 341 PHE 341 543 543 PHE PHE A . n 
A 1 342 GLY 342 544 544 GLY GLY A . n 
A 1 343 LYS 343 545 545 LYS LYS A . n 
A 1 344 GLN 344 546 546 GLN GLN A . n 
A 1 345 GLY 345 547 547 GLY GLY A . n 
A 1 346 THR 346 548 548 THR THR A . n 
A 1 347 GLY 347 549 549 GLY GLY A . n 
A 1 348 ARG 348 550 550 ARG ARG A . n 
A 1 349 ASP 349 551 551 ASP ASP A . n 
A 1 350 ASN 350 552 552 ASN ASN A . n 
A 1 351 VAL 351 553 553 VAL VAL A . n 
A 1 352 ASP 352 554 554 ASP ASP A . n 
A 1 353 ALA 353 555 555 ALA ALA A . n 
A 1 354 ASP 354 556 556 ASP ASP A . n 
A 1 355 LYS 355 557 557 LYS LYS A . n 
A 1 356 VAL 356 558 558 VAL VAL A . n 
A 1 357 MET 357 559 559 MET MET A . n 
A 1 358 ILE 358 560 560 ILE ILE A . n 
A 1 359 THR 359 561 561 THR THR A . n 
A 1 360 ASN 360 562 562 ASN ASN A . n 
A 1 361 GLU 361 563 563 GLU GLU A . n 
A 1 362 GLU 362 564 564 GLU GLU A . n 
A 1 363 GLU 363 565 565 GLU GLU A . n 
A 1 364 ILE 364 566 566 ILE ILE A . n 
A 1 365 LYS 365 567 567 LYS LYS A . n 
A 1 366 THR 366 568 568 THR THR A . n 
A 1 367 THR 367 569 569 THR THR A . n 
A 1 368 ASN 368 570 570 ASN ASN A . n 
A 1 369 PRO 369 571 571 PRO PRO A . n 
A 1 370 VAL 370 572 572 VAL VAL A . n 
A 1 371 ALA 371 573 573 ALA ALA A . n 
A 1 372 THR 372 574 574 THR THR A . n 
A 1 373 GLU 373 575 575 GLU GLU A . n 
A 1 374 SER 374 576 576 SER SER A . n 
A 1 375 TYR 375 577 577 TYR TYR A . n 
A 1 376 GLY 376 578 578 GLY GLY A . n 
A 1 377 GLN 377 579 579 GLN GLN A . n 
A 1 378 VAL 378 580 580 VAL VAL A . n 
A 1 379 ALA 379 581 581 ALA ALA A . n 
A 1 380 THR 380 582 582 THR THR A . n 
A 1 381 ASN 381 583 583 ASN ASN A . n 
A 1 382 HIS 382 584 584 HIS HIS A . n 
A 1 383 GLN 383 585 585 GLN GLN A . n 
A 1 384 SER 384 586 586 SER SER A . n 
A 1 385 ALA 385 587 587 ALA ALA A . n 
A 1 386 GLN 386 588 588 GLN GLN A . n 
A 1 387 ALA 387 589 589 ALA ALA A . n 
A 1 388 GLN 388 590 590 GLN GLN A . n 
A 1 389 ALA 389 591 591 ALA ALA A . n 
A 1 390 GLN 390 592 592 GLN GLN A . n 
A 1 391 THR 391 593 593 THR THR A . n 
A 1 392 GLY 392 594 594 GLY GLY A . n 
A 1 393 TRP 393 595 595 TRP TRP A . n 
A 1 394 VAL 394 596 596 VAL VAL A . n 
A 1 395 GLN 395 597 597 GLN GLN A . n 
A 1 396 ASN 396 598 598 ASN ASN A . n 
A 1 397 GLN 397 599 599 GLN GLN A . n 
A 1 398 GLY 398 600 600 GLY GLY A . n 
A 1 399 ILE 399 601 601 ILE ILE A . n 
A 1 400 LEU 400 602 602 LEU LEU A . n 
A 1 401 PRO 401 603 603 PRO PRO A . n 
A 1 402 GLY 402 604 604 GLY GLY A . n 
A 1 403 MET 403 605 605 MET MET A . n 
A 1 404 VAL 404 606 606 VAL VAL A . n 
A 1 405 TRP 405 607 607 TRP TRP A . n 
A 1 406 GLN 406 608 608 GLN GLN A . n 
A 1 407 ASP 407 609 609 ASP ASP A . n 
A 1 408 ARG 408 610 610 ARG ARG A . n 
A 1 409 ASP 409 611 611 ASP ASP A . n 
A 1 410 VAL 410 612 612 VAL VAL A . n 
A 1 411 TYR 411 613 613 TYR TYR A . n 
A 1 412 LEU 412 614 614 LEU LEU A . n 
A 1 413 GLN 413 615 615 GLN GLN A . n 
A 1 414 GLY 414 616 616 GLY GLY A . n 
A 1 415 PRO 415 617 617 PRO PRO A . n 
A 1 416 ILE 416 618 618 ILE ILE A . n 
A 1 417 TRP 417 619 619 TRP TRP A . n 
A 1 418 ALA 418 620 620 ALA ALA A . n 
A 1 419 LYS 419 621 621 LYS LYS A . n 
A 1 420 ILE 420 622 622 ILE ILE A . n 
A 1 421 PRO 421 623 623 PRO PRO A . n 
A 1 422 HIS 422 624 624 HIS HIS A . n 
A 1 423 THR 423 625 625 THR THR A . n 
A 1 424 ASP 424 626 626 ASP ASP A . n 
A 1 425 GLY 425 627 627 GLY GLY A . n 
A 1 426 ASN 426 628 628 ASN ASN A . n 
A 1 427 PHE 427 629 629 PHE PHE A . n 
A 1 428 HIS 428 630 630 HIS HIS A . n 
A 1 429 PRO 429 631 631 PRO PRO A . n 
A 1 430 SER 430 632 632 SER SER A . n 
A 1 431 PRO 431 633 633 PRO PRO A . n 
A 1 432 LEU 432 634 634 LEU LEU A . n 
A 1 433 MET 433 635 635 MET MET A . n 
A 1 434 GLY 434 636 636 GLY GLY A . n 
A 1 435 GLY 435 637 637 GLY GLY A . n 
A 1 436 PHE 436 638 638 PHE PHE A . n 
A 1 437 GLY 437 639 639 GLY GLY A . n 
A 1 438 MET 438 640 640 MET MET A . n 
A 1 439 LYS 439 641 641 LYS LYS A . n 
A 1 440 HIS 440 642 642 HIS HIS A . n 
A 1 441 PRO 441 643 643 PRO PRO A . n 
A 1 442 PRO 442 644 644 PRO PRO A . n 
A 1 443 PRO 443 645 645 PRO PRO A . n 
A 1 444 GLN 444 646 646 GLN GLN A . n 
A 1 445 ILE 445 647 647 ILE ILE A . n 
A 1 446 LEU 446 648 648 LEU LEU A . n 
A 1 447 ILE 447 649 649 ILE ILE A . n 
A 1 448 LYS 448 650 650 LYS LYS A . n 
A 1 449 ASN 449 651 651 ASN ASN A . n 
A 1 450 THR 450 652 652 THR THR A . n 
A 1 451 PRO 451 653 653 PRO PRO A . n 
A 1 452 VAL 452 654 654 VAL VAL A . n 
A 1 453 PRO 453 655 655 PRO PRO A . n 
A 1 454 ALA 454 656 656 ALA ALA A . n 
A 1 455 ASP 455 657 657 ASP ASP A . n 
A 1 456 PRO 456 658 658 PRO PRO A . n 
A 1 457 PRO 457 659 659 PRO PRO A . n 
A 1 458 THR 458 660 660 THR THR A . n 
A 1 459 ALA 459 661 661 ALA ALA A . n 
A 1 460 PHE 460 662 662 PHE PHE A . n 
A 1 461 ASN 461 663 663 ASN ASN A . n 
A 1 462 LYS 462 664 664 LYS LYS A . n 
A 1 463 ASP 463 665 665 ASP ASP A . n 
A 1 464 LYS 464 666 666 LYS LYS A . n 
A 1 465 LEU 465 667 667 LEU LEU A . n 
A 1 466 ASN 466 668 668 ASN ASN A . n 
A 1 467 SER 467 669 669 SER SER A . n 
A 1 468 PHE 468 670 670 PHE PHE A . n 
A 1 469 ILE 469 671 671 ILE ILE A . n 
A 1 470 THR 470 672 672 THR THR A . n 
A 1 471 GLN 471 673 673 GLN GLN A . n 
A 1 472 TYR 472 674 674 TYR TYR A . n 
A 1 473 SER 473 675 675 SER SER A . n 
A 1 474 THR 474 676 676 THR THR A . n 
A 1 475 GLY 475 677 677 GLY GLY A . n 
A 1 476 GLN 476 678 678 GLN GLN A . n 
A 1 477 VAL 477 679 679 VAL VAL A . n 
A 1 478 SER 478 680 680 SER SER A . n 
A 1 479 VAL 479 681 681 VAL VAL A . n 
A 1 480 GLU 480 682 682 GLU GLU A . n 
A 1 481 ILE 481 683 683 ILE ILE A . n 
A 1 482 GLU 482 684 684 GLU GLU A . n 
A 1 483 TRP 483 685 685 TRP TRP A . n 
A 1 484 GLU 484 686 686 GLU GLU A . n 
A 1 485 LEU 485 687 687 LEU LEU A . n 
A 1 486 GLN 486 688 688 GLN GLN A . n 
A 1 487 LYS 487 689 ?   ?   ?   A . n 
A 1 488 GLU 488 690 ?   ?   ?   A . n 
A 1 489 ASN 489 691 ?   ?   ?   A . n 
A 1 490 SER 490 692 ?   ?   ?   A . n 
A 1 491 LYS 491 693 ?   ?   ?   A . n 
A 1 492 ARG 492 694 ?   ?   ?   A . n 
A 1 493 TRP 493 695 ?   ?   ?   A . n 
A 1 494 ASN 494 696 ?   ?   ?   A . n 
A 1 495 PRO 495 697 ?   ?   ?   A . n 
A 1 496 GLU 496 698 ?   ?   ?   A . n 
A 1 497 ILE 497 699 ?   ?   ?   A . n 
A 1 498 GLN 498 700 ?   ?   ?   A . n 
A 1 499 TYR 499 701 ?   ?   ?   A . n 
A 1 500 THR 500 702 ?   ?   ?   A . n 
A 1 501 SER 501 703 ?   ?   ?   A . n 
A 1 502 ASN 502 704 ?   ?   ?   A . n 
A 1 503 TYR 503 705 ?   ?   ?   A . n 
A 1 504 TYR 504 706 ?   ?   ?   A . n 
A 1 505 LYS 505 707 ?   ?   ?   A . n 
A 1 506 SER 506 708 ?   ?   ?   A . n 
A 1 507 ASN 507 709 ?   ?   ?   A . n 
A 1 508 ASN 508 710 ?   ?   ?   A . n 
A 1 509 VAL 509 711 ?   ?   ?   A . n 
A 1 510 GLU 510 712 ?   ?   ?   A . n 
A 1 511 PHE 511 713 ?   ?   ?   A . n 
A 1 512 ALA 512 714 ?   ?   ?   A . n 
A 1 513 VAL 513 715 ?   ?   ?   A . n 
A 1 514 ASN 514 716 ?   ?   ?   A . n 
A 1 515 THR 515 717 ?   ?   ?   A . n 
A 1 516 GLU 516 718 ?   ?   ?   A . n 
A 1 517 GLY 517 719 ?   ?   ?   A . n 
A 1 518 VAL 518 720 ?   ?   ?   A . n 
A 1 519 TYR 519 721 ?   ?   ?   A . n 
A 1 520 SER 520 722 ?   ?   ?   A . n 
A 1 521 GLU 521 723 ?   ?   ?   A . n 
A 1 522 PRO 522 724 ?   ?   ?   A . n 
A 1 523 ARG 523 725 ?   ?   ?   A . n 
A 1 524 PRO 524 726 ?   ?   ?   A . n 
A 1 525 ILE 525 727 ?   ?   ?   A . n 
A 1 526 GLY 526 728 ?   ?   ?   A . n 
A 1 527 THR 527 729 ?   ?   ?   A . n 
A 1 528 ARG 528 730 ?   ?   ?   A . n 
A 1 529 TYR 529 731 ?   ?   ?   A . n 
A 1 530 LEU 530 732 ?   ?   ?   A . n 
A 1 531 THR 531 733 ?   ?   ?   A . n 
A 1 532 ARG 532 734 ?   ?   ?   A . n 
A 1 533 ASN 533 735 ?   ?   ?   A . n 
A 1 534 LEU 534 736 ?   ?   ?   A . n 
B 1 1   MET 1   203 ?   ?   ?   B . n 
B 1 2   ALA 2   204 ?   ?   ?   B . n 
B 1 3   SER 3   205 ?   ?   ?   B . n 
B 1 4   GLY 4   206 ?   ?   ?   B . n 
B 1 5   GLY 5   207 ?   ?   ?   B . n 
B 1 6   GLY 6   208 ?   ?   ?   B . n 
B 1 7   ALA 7   209 ?   ?   ?   B . n 
B 1 8   PRO 8   210 ?   ?   ?   B . n 
B 1 9   VAL 9   211 ?   ?   ?   B . n 
B 1 10  ALA 10  212 ?   ?   ?   B . n 
B 1 11  ASP 11  213 ?   ?   ?   B . n 
B 1 12  ASN 12  214 ?   ?   ?   B . n 
B 1 13  ASN 13  215 ?   ?   ?   B . n 
B 1 14  GLU 14  216 ?   ?   ?   B . n 
B 1 15  GLY 15  217 ?   ?   ?   B . n 
B 1 16  ALA 16  218 ?   ?   ?   B . n 
B 1 17  ASP 17  219 ?   ?   ?   B . n 
B 1 18  GLY 18  220 ?   ?   ?   B . n 
B 1 19  VAL 19  221 ?   ?   ?   B . n 
B 1 20  GLY 20  222 ?   ?   ?   B . n 
B 1 21  SER 21  223 ?   ?   ?   B . n 
B 1 22  SER 22  224 ?   ?   ?   B . n 
B 1 23  SER 23  225 ?   ?   ?   B . n 
B 1 24  GLY 24  226 ?   ?   ?   B . n 
B 1 25  ASN 25  227 ?   ?   ?   B . n 
B 1 26  TRP 26  228 ?   ?   ?   B . n 
B 1 27  HIS 27  229 ?   ?   ?   B . n 
B 1 28  CYS 28  230 ?   ?   ?   B . n 
B 1 29  ASP 29  231 ?   ?   ?   B . n 
B 1 30  SER 30  232 ?   ?   ?   B . n 
B 1 31  GLN 31  233 ?   ?   ?   B . n 
B 1 32  TRP 32  234 ?   ?   ?   B . n 
B 1 33  LEU 33  235 ?   ?   ?   B . n 
B 1 34  GLY 34  236 ?   ?   ?   B . n 
B 1 35  ASP 35  237 ?   ?   ?   B . n 
B 1 36  ARG 36  238 ?   ?   ?   B . n 
B 1 37  VAL 37  239 ?   ?   ?   B . n 
B 1 38  ILE 38  240 ?   ?   ?   B . n 
B 1 39  THR 39  241 ?   ?   ?   B . n 
B 1 40  THR 40  242 ?   ?   ?   B . n 
B 1 41  SER 41  243 ?   ?   ?   B . n 
B 1 42  THR 42  244 ?   ?   ?   B . n 
B 1 43  ARG 43  245 ?   ?   ?   B . n 
B 1 44  THR 44  246 ?   ?   ?   B . n 
B 1 45  TRP 45  247 ?   ?   ?   B . n 
B 1 46  ALA 46  248 ?   ?   ?   B . n 
B 1 47  LEU 47  249 ?   ?   ?   B . n 
B 1 48  PRO 48  250 ?   ?   ?   B . n 
B 1 49  THR 49  251 ?   ?   ?   B . n 
B 1 50  TYR 50  252 ?   ?   ?   B . n 
B 1 51  ASN 51  253 ?   ?   ?   B . n 
B 1 52  ASN 52  254 ?   ?   ?   B . n 
B 1 53  HIS 53  255 ?   ?   ?   B . n 
B 1 54  LEU 54  256 ?   ?   ?   B . n 
B 1 55  TYR 55  257 ?   ?   ?   B . n 
B 1 56  LYS 56  258 ?   ?   ?   B . n 
B 1 57  GLN 57  259 ?   ?   ?   B . n 
B 1 58  ILE 58  260 ?   ?   ?   B . n 
B 1 59  SER 59  261 ?   ?   ?   B . n 
B 1 60  ASN 60  262 ?   ?   ?   B . n 
B 1 61  SER 61  263 ?   ?   ?   B . n 
B 1 62  THR 62  264 ?   ?   ?   B . n 
B 1 63  SER 63  265 ?   ?   ?   B . n 
B 1 64  GLY 64  266 ?   ?   ?   B . n 
B 1 65  GLY 65  267 ?   ?   ?   B . n 
B 1 66  SER 66  268 ?   ?   ?   B . n 
B 1 67  SER 67  269 ?   ?   ?   B . n 
B 1 68  ASN 68  270 ?   ?   ?   B . n 
B 1 69  ASP 69  271 ?   ?   ?   B . n 
B 1 70  ASN 70  272 ?   ?   ?   B . n 
B 1 71  ALA 71  273 ?   ?   ?   B . n 
B 1 72  TYR 72  274 ?   ?   ?   B . n 
B 1 73  PHE 73  275 ?   ?   ?   B . n 
B 1 74  GLY 74  276 ?   ?   ?   B . n 
B 1 75  TYR 75  277 ?   ?   ?   B . n 
B 1 76  SER 76  278 ?   ?   ?   B . n 
B 1 77  THR 77  279 ?   ?   ?   B . n 
B 1 78  PRO 78  280 ?   ?   ?   B . n 
B 1 79  TRP 79  281 ?   ?   ?   B . n 
B 1 80  GLY 80  282 ?   ?   ?   B . n 
B 1 81  TYR 81  283 ?   ?   ?   B . n 
B 1 82  PHE 82  284 ?   ?   ?   B . n 
B 1 83  ASP 83  285 ?   ?   ?   B . n 
B 1 84  PHE 84  286 ?   ?   ?   B . n 
B 1 85  ASN 85  287 ?   ?   ?   B . n 
B 1 86  ARG 86  288 ?   ?   ?   B . n 
B 1 87  PHE 87  289 ?   ?   ?   B . n 
B 1 88  HIS 88  290 ?   ?   ?   B . n 
B 1 89  CYS 89  291 ?   ?   ?   B . n 
B 1 90  HIS 90  292 ?   ?   ?   B . n 
B 1 91  PHE 91  293 ?   ?   ?   B . n 
B 1 92  SER 92  294 ?   ?   ?   B . n 
B 1 93  PRO 93  295 ?   ?   ?   B . n 
B 1 94  ARG 94  296 ?   ?   ?   B . n 
B 1 95  ASP 95  297 ?   ?   ?   B . n 
B 1 96  TRP 96  298 ?   ?   ?   B . n 
B 1 97  GLN 97  299 ?   ?   ?   B . n 
B 1 98  ARG 98  300 ?   ?   ?   B . n 
B 1 99  LEU 99  301 ?   ?   ?   B . n 
B 1 100 ILE 100 302 ?   ?   ?   B . n 
B 1 101 ASN 101 303 ?   ?   ?   B . n 
B 1 102 ASN 102 304 ?   ?   ?   B . n 
B 1 103 ASN 103 305 ?   ?   ?   B . n 
B 1 104 TRP 104 306 ?   ?   ?   B . n 
B 1 105 GLY 105 307 ?   ?   ?   B . n 
B 1 106 PHE 106 308 ?   ?   ?   B . n 
B 1 107 ARG 107 309 ?   ?   ?   B . n 
B 1 108 PRO 108 310 ?   ?   ?   B . n 
B 1 109 LYS 109 311 ?   ?   ?   B . n 
B 1 110 ARG 110 312 ?   ?   ?   B . n 
B 1 111 LEU 111 313 ?   ?   ?   B . n 
B 1 112 ASN 112 314 ?   ?   ?   B . n 
B 1 113 PHE 113 315 ?   ?   ?   B . n 
B 1 114 LYS 114 316 ?   ?   ?   B . n 
B 1 115 LEU 115 317 ?   ?   ?   B . n 
B 1 116 PHE 116 318 ?   ?   ?   B . n 
B 1 117 ASN 117 319 ?   ?   ?   B . n 
B 1 118 ILE 118 320 ?   ?   ?   B . n 
B 1 119 GLN 119 321 ?   ?   ?   B . n 
B 1 120 VAL 120 322 ?   ?   ?   B . n 
B 1 121 LYS 121 323 ?   ?   ?   B . n 
B 1 122 GLU 122 324 ?   ?   ?   B . n 
B 1 123 VAL 123 325 ?   ?   ?   B . n 
B 1 124 THR 124 326 ?   ?   ?   B . n 
B 1 125 ASP 125 327 ?   ?   ?   B . n 
B 1 126 ASN 126 328 ?   ?   ?   B . n 
B 1 127 ASN 127 329 ?   ?   ?   B . n 
B 1 128 GLY 128 330 ?   ?   ?   B . n 
B 1 129 VAL 129 331 ?   ?   ?   B . n 
B 1 130 LYS 130 332 ?   ?   ?   B . n 
B 1 131 THR 131 333 ?   ?   ?   B . n 
B 1 132 ILE 132 334 ?   ?   ?   B . n 
B 1 133 ALA 133 335 ?   ?   ?   B . n 
B 1 134 ASN 134 336 ?   ?   ?   B . n 
B 1 135 ASN 135 337 ?   ?   ?   B . n 
B 1 136 LEU 136 338 ?   ?   ?   B . n 
B 1 137 THR 137 339 ?   ?   ?   B . n 
B 1 138 SER 138 340 ?   ?   ?   B . n 
B 1 139 THR 139 341 ?   ?   ?   B . n 
B 1 140 VAL 140 342 ?   ?   ?   B . n 
B 1 141 GLN 141 343 ?   ?   ?   B . n 
B 1 142 VAL 142 344 ?   ?   ?   B . n 
B 1 143 PHE 143 345 ?   ?   ?   B . n 
B 1 144 THR 144 346 ?   ?   ?   B . n 
B 1 145 ASP 145 347 ?   ?   ?   B . n 
B 1 146 SER 146 348 ?   ?   ?   B . n 
B 1 147 ASP 147 349 ?   ?   ?   B . n 
B 1 148 TYR 148 350 ?   ?   ?   B . n 
B 1 149 GLN 149 351 ?   ?   ?   B . n 
B 1 150 LEU 150 352 ?   ?   ?   B . n 
B 1 151 PRO 151 353 ?   ?   ?   B . n 
B 1 152 TYR 152 354 ?   ?   ?   B . n 
B 1 153 VAL 153 355 ?   ?   ?   B . n 
B 1 154 LEU 154 356 ?   ?   ?   B . n 
B 1 155 GLY 155 357 ?   ?   ?   B . n 
B 1 156 SER 156 358 ?   ?   ?   B . n 
B 1 157 ALA 157 359 ?   ?   ?   B . n 
B 1 158 HIS 158 360 ?   ?   ?   B . n 
B 1 159 GLU 159 361 ?   ?   ?   B . n 
B 1 160 GLY 160 362 ?   ?   ?   B . n 
B 1 161 CYS 161 363 ?   ?   ?   B . n 
B 1 162 LEU 162 364 ?   ?   ?   B . n 
B 1 163 PRO 163 365 ?   ?   ?   B . n 
B 1 164 PRO 164 366 ?   ?   ?   B . n 
B 1 165 PHE 165 367 ?   ?   ?   B . n 
B 1 166 PRO 166 368 ?   ?   ?   B . n 
B 1 167 ALA 167 369 ?   ?   ?   B . n 
B 1 168 ASP 168 370 ?   ?   ?   B . n 
B 1 169 VAL 169 371 ?   ?   ?   B . n 
B 1 170 PHE 170 372 ?   ?   ?   B . n 
B 1 171 MET 171 373 ?   ?   ?   B . n 
B 1 172 ILE 172 374 ?   ?   ?   B . n 
B 1 173 PRO 173 375 ?   ?   ?   B . n 
B 1 174 GLN 174 376 ?   ?   ?   B . n 
B 1 175 TYR 175 377 ?   ?   ?   B . n 
B 1 176 GLY 176 378 ?   ?   ?   B . n 
B 1 177 TYR 177 379 ?   ?   ?   B . n 
B 1 178 LEU 178 380 ?   ?   ?   B . n 
B 1 179 THR 179 381 ?   ?   ?   B . n 
B 1 180 LEU 180 382 ?   ?   ?   B . n 
B 1 181 ASN 181 383 ?   ?   ?   B . n 
B 1 182 ASP 182 384 ?   ?   ?   B . n 
B 1 183 GLY 183 385 ?   ?   ?   B . n 
B 1 184 SER 184 386 ?   ?   ?   B . n 
B 1 185 GLN 185 387 ?   ?   ?   B . n 
B 1 186 ALA 186 388 ?   ?   ?   B . n 
B 1 187 VAL 187 389 ?   ?   ?   B . n 
B 1 188 GLY 188 390 ?   ?   ?   B . n 
B 1 189 ARG 189 391 ?   ?   ?   B . n 
B 1 190 SER 190 392 ?   ?   ?   B . n 
B 1 191 SER 191 393 ?   ?   ?   B . n 
B 1 192 PHE 192 394 ?   ?   ?   B . n 
B 1 193 TYR 193 395 ?   ?   ?   B . n 
B 1 194 CYS 194 396 ?   ?   ?   B . n 
B 1 195 LEU 195 397 ?   ?   ?   B . n 
B 1 196 GLU 196 398 ?   ?   ?   B . n 
B 1 197 TYR 197 399 ?   ?   ?   B . n 
B 1 198 PHE 198 400 ?   ?   ?   B . n 
B 1 199 PRO 199 401 ?   ?   ?   B . n 
B 1 200 SER 200 402 ?   ?   ?   B . n 
B 1 201 GLN 201 403 ?   ?   ?   B . n 
B 1 202 MET 202 404 ?   ?   ?   B . n 
B 1 203 LEU 203 405 ?   ?   ?   B . n 
B 1 204 ARG 204 406 ?   ?   ?   B . n 
B 1 205 THR 205 407 ?   ?   ?   B . n 
B 1 206 GLY 206 408 ?   ?   ?   B . n 
B 1 207 ASN 207 409 ?   ?   ?   B . n 
B 1 208 ASN 208 410 ?   ?   ?   B . n 
B 1 209 PHE 209 411 ?   ?   ?   B . n 
B 1 210 GLN 210 412 ?   ?   ?   B . n 
B 1 211 PHE 211 413 ?   ?   ?   B . n 
B 1 212 SER 212 414 ?   ?   ?   B . n 
B 1 213 TYR 213 415 ?   ?   ?   B . n 
B 1 214 GLU 214 416 ?   ?   ?   B . n 
B 1 215 PHE 215 417 417 PHE PHE B . n 
B 1 216 GLU 216 418 418 GLU GLU B . n 
B 1 217 ASN 217 419 419 ASN ASN B . n 
B 1 218 VAL 218 420 420 VAL VAL B . n 
B 1 219 PRO 219 421 421 PRO PRO B . n 
B 1 220 PHE 220 422 422 PHE PHE B . n 
B 1 221 HIS 221 423 423 HIS HIS B . n 
B 1 222 SER 222 424 424 SER SER B . n 
B 1 223 SER 223 425 425 SER SER B . n 
B 1 224 TYR 224 426 426 TYR TYR B . n 
B 1 225 ALA 225 427 427 ALA ALA B . n 
B 1 226 HIS 226 428 428 HIS HIS B . n 
B 1 227 SER 227 429 429 SER SER B . n 
B 1 228 GLN 228 430 430 GLN GLN B . n 
B 1 229 SER 229 431 431 SER SER B . n 
B 1 230 LEU 230 432 432 LEU LEU B . n 
B 1 231 ASP 231 433 433 ASP ASP B . n 
B 1 232 ARG 232 434 434 ARG ARG B . n 
B 1 233 LEU 233 435 435 LEU LEU B . n 
B 1 234 MET 234 436 436 MET MET B . n 
B 1 235 ASN 235 437 437 ASN ASN B . n 
B 1 236 PRO 236 438 438 PRO PRO B . n 
B 1 237 LEU 237 439 439 LEU LEU B . n 
B 1 238 ILE 238 440 440 ILE ILE B . n 
B 1 239 ASP 239 441 441 ASP ASP B . n 
B 1 240 GLN 240 442 442 GLN GLN B . n 
B 1 241 TYR 241 443 443 TYR TYR B . n 
B 1 242 LEU 242 444 444 LEU LEU B . n 
B 1 243 TYR 243 445 445 TYR TYR B . n 
B 1 244 TYR 244 446 446 TYR TYR B . n 
B 1 245 LEU 245 447 447 LEU LEU B . n 
B 1 246 SER 246 448 448 SER SER B . n 
B 1 247 LYS 247 449 449 LYS LYS B . n 
B 1 248 THR 248 450 450 THR THR B . n 
B 1 249 ILE 249 451 451 ILE ILE B . n 
B 1 250 ASN 250 452 452 ASN ASN B . n 
B 1 251 GLY 251 453 453 GLY GLY B . n 
B 1 252 SER 252 454 454 SER SER B . n 
B 1 253 GLY 253 455 455 GLY GLY B . n 
B 1 254 GLN 254 456 456 GLN GLN B . n 
B 1 255 ASN 255 457 457 ASN ASN B . n 
B 1 256 GLN 256 458 458 GLN GLN B . n 
B 1 257 GLN 257 459 459 GLN GLN B . n 
B 1 258 THR 258 460 460 THR THR B . n 
B 1 259 LEU 259 461 461 LEU LEU B . n 
B 1 260 LYS 260 462 462 LYS LYS B . n 
B 1 261 PHE 261 463 463 PHE PHE B . n 
B 1 262 SER 262 464 464 SER SER B . n 
B 1 263 VAL 263 465 465 VAL VAL B . n 
B 1 264 ALA 264 466 466 ALA ALA B . n 
B 1 265 GLY 265 467 467 GLY GLY B . n 
B 1 266 PRO 266 468 468 PRO PRO B . n 
B 1 267 SER 267 469 469 SER SER B . n 
B 1 268 ASN 268 470 470 ASN ASN B . n 
B 1 269 MET 269 471 471 MET MET B . n 
B 1 270 ALA 270 472 472 ALA ALA B . n 
B 1 271 VAL 271 473 473 VAL VAL B . n 
B 1 272 GLN 272 474 474 GLN GLN B . n 
B 1 273 GLY 273 475 475 GLY GLY B . n 
B 1 274 ARG 274 476 476 ARG ARG B . n 
B 1 275 ASN 275 477 477 ASN ASN B . n 
B 1 276 TYR 276 478 478 TYR TYR B . n 
B 1 277 ILE 277 479 479 ILE ILE B . n 
B 1 278 PRO 278 480 480 PRO PRO B . n 
B 1 279 GLY 279 481 481 GLY GLY B . n 
B 1 280 PRO 280 482 482 PRO PRO B . n 
B 1 281 SER 281 483 483 SER SER B . n 
B 1 282 TYR 282 484 484 TYR TYR B . n 
B 1 283 ARG 283 485 485 ARG ARG B . n 
B 1 284 GLN 284 486 486 GLN GLN B . n 
B 1 285 GLN 285 487 487 GLN GLN B . n 
B 1 286 ARG 286 488 488 ARG ARG B . n 
B 1 287 VAL 287 489 489 VAL VAL B . n 
B 1 288 SER 288 490 490 SER SER B . n 
B 1 289 THR 289 491 491 THR THR B . n 
B 1 290 THR 290 492 492 THR THR B . n 
B 1 291 VAL 291 493 493 VAL VAL B . n 
B 1 292 THR 292 494 494 THR THR B . n 
B 1 293 GLN 293 495 495 GLN GLN B . n 
B 1 294 ASN 294 496 496 ASN ASN B . n 
B 1 295 ASN 295 497 497 ASN ASN B . n 
B 1 296 ASN 296 498 498 ASN ASN B . n 
B 1 297 SER 297 499 499 SER SER B . n 
B 1 298 GLU 298 500 500 GLU GLU B . n 
B 1 299 PHE 299 501 501 PHE PHE B . n 
B 1 300 ALA 300 502 502 ALA ALA B . n 
B 1 301 TRP 301 503 503 TRP TRP B . n 
B 1 302 PRO 302 504 504 PRO PRO B . n 
B 1 303 GLY 303 505 505 GLY GLY B . n 
B 1 304 ALA 304 506 506 ALA ALA B . n 
B 1 305 SER 305 507 507 SER SER B . n 
B 1 306 SER 306 508 508 SER SER B . n 
B 1 307 TRP 307 509 509 TRP TRP B . n 
B 1 308 ALA 308 510 510 ALA ALA B . n 
B 1 309 LEU 309 511 511 LEU LEU B . n 
B 1 310 ASN 310 512 512 ASN ASN B . n 
B 1 311 GLY 311 513 513 GLY GLY B . n 
B 1 312 ARG 312 514 514 ARG ARG B . n 
B 1 313 ASN 313 515 515 ASN ASN B . n 
B 1 314 SER 314 516 516 SER SER B . n 
B 1 315 LEU 315 517 517 LEU LEU B . n 
B 1 316 MET 316 518 518 MET MET B . n 
B 1 317 ASN 317 519 519 ASN ASN B . n 
B 1 318 PRO 318 520 520 PRO PRO B . n 
B 1 319 GLY 319 521 521 GLY GLY B . n 
B 1 320 PRO 320 522 522 PRO PRO B . n 
B 1 321 ALA 321 523 523 ALA ALA B . n 
B 1 322 MET 322 524 524 MET MET B . n 
B 1 323 ALA 323 525 525 ALA ALA B . n 
B 1 324 SER 324 526 526 SER SER B . n 
B 1 325 HIS 325 527 527 HIS HIS B . n 
B 1 326 LYS 326 528 528 LYS LYS B . n 
B 1 327 GLU 327 529 529 GLU GLU B . n 
B 1 328 GLY 328 530 530 GLY GLY B . n 
B 1 329 GLU 329 531 531 GLU GLU B . n 
B 1 330 ASP 330 532 532 ASP ASP B . n 
B 1 331 ARG 331 533 533 ARG ARG B . n 
B 1 332 PHE 332 534 534 PHE PHE B . n 
B 1 333 PHE 333 535 535 PHE PHE B . n 
B 1 334 PRO 334 536 536 PRO PRO B . n 
B 1 335 LEU 335 537 537 LEU LEU B . n 
B 1 336 SER 336 538 538 SER SER B . n 
B 1 337 GLY 337 539 539 GLY GLY B . n 
B 1 338 SER 338 540 540 SER SER B . n 
B 1 339 LEU 339 541 541 LEU LEU B . n 
B 1 340 ILE 340 542 542 ILE ILE B . n 
B 1 341 PHE 341 543 543 PHE PHE B . n 
B 1 342 GLY 342 544 ?   ?   ?   B . n 
B 1 343 LYS 343 545 ?   ?   ?   B . n 
B 1 344 GLN 344 546 ?   ?   ?   B . n 
B 1 345 GLY 345 547 ?   ?   ?   B . n 
B 1 346 THR 346 548 ?   ?   ?   B . n 
B 1 347 GLY 347 549 ?   ?   ?   B . n 
B 1 348 ARG 348 550 ?   ?   ?   B . n 
B 1 349 ASP 349 551 ?   ?   ?   B . n 
B 1 350 ASN 350 552 ?   ?   ?   B . n 
B 1 351 VAL 351 553 ?   ?   ?   B . n 
B 1 352 ASP 352 554 ?   ?   ?   B . n 
B 1 353 ALA 353 555 ?   ?   ?   B . n 
B 1 354 ASP 354 556 ?   ?   ?   B . n 
B 1 355 LYS 355 557 ?   ?   ?   B . n 
B 1 356 VAL 356 558 558 VAL VAL B . n 
B 1 357 MET 357 559 559 MET MET B . n 
B 1 358 ILE 358 560 560 ILE ILE B . n 
B 1 359 THR 359 561 561 THR THR B . n 
B 1 360 ASN 360 562 562 ASN ASN B . n 
B 1 361 GLU 361 563 563 GLU GLU B . n 
B 1 362 GLU 362 564 564 GLU GLU B . n 
B 1 363 GLU 363 565 565 GLU GLU B . n 
B 1 364 ILE 364 566 566 ILE ILE B . n 
B 1 365 LYS 365 567 567 LYS LYS B . n 
B 1 366 THR 366 568 568 THR THR B . n 
B 1 367 THR 367 569 569 THR THR B . n 
B 1 368 ASN 368 570 570 ASN ASN B . n 
B 1 369 PRO 369 571 571 PRO PRO B . n 
B 1 370 VAL 370 572 572 VAL VAL B . n 
B 1 371 ALA 371 573 573 ALA ALA B . n 
B 1 372 THR 372 574 574 THR THR B . n 
B 1 373 GLU 373 575 575 GLU GLU B . n 
B 1 374 SER 374 576 576 SER SER B . n 
B 1 375 TYR 375 577 577 TYR TYR B . n 
B 1 376 GLY 376 578 578 GLY GLY B . n 
B 1 377 GLN 377 579 579 GLN GLN B . n 
B 1 378 VAL 378 580 580 VAL VAL B . n 
B 1 379 ALA 379 581 581 ALA ALA B . n 
B 1 380 THR 380 582 582 THR THR B . n 
B 1 381 ASN 381 583 583 ASN ASN B . n 
B 1 382 HIS 382 584 584 HIS HIS B . n 
B 1 383 GLN 383 585 585 GLN GLN B . n 
B 1 384 SER 384 586 586 SER SER B . n 
B 1 385 ALA 385 587 587 ALA ALA B . n 
B 1 386 GLN 386 588 588 GLN GLN B . n 
B 1 387 ALA 387 589 589 ALA ALA B . n 
B 1 388 GLN 388 590 590 GLN GLN B . n 
B 1 389 ALA 389 591 591 ALA ALA B . n 
B 1 390 GLN 390 592 592 GLN GLN B . n 
B 1 391 THR 391 593 593 THR THR B . n 
B 1 392 GLY 392 594 594 GLY GLY B . n 
B 1 393 TRP 393 595 595 TRP TRP B . n 
B 1 394 VAL 394 596 596 VAL VAL B . n 
B 1 395 GLN 395 597 597 GLN GLN B . n 
B 1 396 ASN 396 598 598 ASN ASN B . n 
B 1 397 GLN 397 599 599 GLN GLN B . n 
B 1 398 GLY 398 600 600 GLY GLY B . n 
B 1 399 ILE 399 601 601 ILE ILE B . n 
B 1 400 LEU 400 602 602 LEU LEU B . n 
B 1 401 PRO 401 603 603 PRO PRO B . n 
B 1 402 GLY 402 604 604 GLY GLY B . n 
B 1 403 MET 403 605 605 MET MET B . n 
B 1 404 VAL 404 606 606 VAL VAL B . n 
B 1 405 TRP 405 607 607 TRP TRP B . n 
B 1 406 GLN 406 608 608 GLN GLN B . n 
B 1 407 ASP 407 609 609 ASP ASP B . n 
B 1 408 ARG 408 610 610 ARG ARG B . n 
B 1 409 ASP 409 611 611 ASP ASP B . n 
B 1 410 VAL 410 612 612 VAL VAL B . n 
B 1 411 TYR 411 613 613 TYR TYR B . n 
B 1 412 LEU 412 614 614 LEU LEU B . n 
B 1 413 GLN 413 615 615 GLN GLN B . n 
B 1 414 GLY 414 616 616 GLY GLY B . n 
B 1 415 PRO 415 617 617 PRO PRO B . n 
B 1 416 ILE 416 618 618 ILE ILE B . n 
B 1 417 TRP 417 619 619 TRP TRP B . n 
B 1 418 ALA 418 620 620 ALA ALA B . n 
B 1 419 LYS 419 621 621 LYS LYS B . n 
B 1 420 ILE 420 622 622 ILE ILE B . n 
B 1 421 PRO 421 623 623 PRO PRO B . n 
B 1 422 HIS 422 624 624 HIS HIS B . n 
B 1 423 THR 423 625 625 THR THR B . n 
B 1 424 ASP 424 626 626 ASP ASP B . n 
B 1 425 GLY 425 627 627 GLY GLY B . n 
B 1 426 ASN 426 628 628 ASN ASN B . n 
B 1 427 PHE 427 629 629 PHE PHE B . n 
B 1 428 HIS 428 630 630 HIS HIS B . n 
B 1 429 PRO 429 631 631 PRO PRO B . n 
B 1 430 SER 430 632 632 SER SER B . n 
B 1 431 PRO 431 633 633 PRO PRO B . n 
B 1 432 LEU 432 634 634 LEU LEU B . n 
B 1 433 MET 433 635 635 MET MET B . n 
B 1 434 GLY 434 636 636 GLY GLY B . n 
B 1 435 GLY 435 637 637 GLY GLY B . n 
B 1 436 PHE 436 638 638 PHE PHE B . n 
B 1 437 GLY 437 639 639 GLY GLY B . n 
B 1 438 MET 438 640 640 MET MET B . n 
B 1 439 LYS 439 641 641 LYS LYS B . n 
B 1 440 HIS 440 642 642 HIS HIS B . n 
B 1 441 PRO 441 643 643 PRO PRO B . n 
B 1 442 PRO 442 644 644 PRO PRO B . n 
B 1 443 PRO 443 645 ?   ?   ?   B . n 
B 1 444 GLN 444 646 ?   ?   ?   B . n 
B 1 445 ILE 445 647 ?   ?   ?   B . n 
B 1 446 LEU 446 648 ?   ?   ?   B . n 
B 1 447 ILE 447 649 ?   ?   ?   B . n 
B 1 448 LYS 448 650 ?   ?   ?   B . n 
B 1 449 ASN 449 651 ?   ?   ?   B . n 
B 1 450 THR 450 652 ?   ?   ?   B . n 
B 1 451 PRO 451 653 ?   ?   ?   B . n 
B 1 452 VAL 452 654 ?   ?   ?   B . n 
B 1 453 PRO 453 655 ?   ?   ?   B . n 
B 1 454 ALA 454 656 ?   ?   ?   B . n 
B 1 455 ASP 455 657 ?   ?   ?   B . n 
B 1 456 PRO 456 658 ?   ?   ?   B . n 
B 1 457 PRO 457 659 ?   ?   ?   B . n 
B 1 458 THR 458 660 ?   ?   ?   B . n 
B 1 459 ALA 459 661 ?   ?   ?   B . n 
B 1 460 PHE 460 662 ?   ?   ?   B . n 
B 1 461 ASN 461 663 ?   ?   ?   B . n 
B 1 462 LYS 462 664 ?   ?   ?   B . n 
B 1 463 ASP 463 665 ?   ?   ?   B . n 
B 1 464 LYS 464 666 ?   ?   ?   B . n 
B 1 465 LEU 465 667 ?   ?   ?   B . n 
B 1 466 ASN 466 668 ?   ?   ?   B . n 
B 1 467 SER 467 669 ?   ?   ?   B . n 
B 1 468 PHE 468 670 ?   ?   ?   B . n 
B 1 469 ILE 469 671 ?   ?   ?   B . n 
B 1 470 THR 470 672 ?   ?   ?   B . n 
B 1 471 GLN 471 673 ?   ?   ?   B . n 
B 1 472 TYR 472 674 ?   ?   ?   B . n 
B 1 473 SER 473 675 ?   ?   ?   B . n 
B 1 474 THR 474 676 ?   ?   ?   B . n 
B 1 475 GLY 475 677 ?   ?   ?   B . n 
B 1 476 GLN 476 678 ?   ?   ?   B . n 
B 1 477 VAL 477 679 ?   ?   ?   B . n 
B 1 478 SER 478 680 ?   ?   ?   B . n 
B 1 479 VAL 479 681 ?   ?   ?   B . n 
B 1 480 GLU 480 682 ?   ?   ?   B . n 
B 1 481 ILE 481 683 ?   ?   ?   B . n 
B 1 482 GLU 482 684 ?   ?   ?   B . n 
B 1 483 TRP 483 685 ?   ?   ?   B . n 
B 1 484 GLU 484 686 ?   ?   ?   B . n 
B 1 485 LEU 485 687 ?   ?   ?   B . n 
B 1 486 GLN 486 688 ?   ?   ?   B . n 
B 1 487 LYS 487 689 ?   ?   ?   B . n 
B 1 488 GLU 488 690 ?   ?   ?   B . n 
B 1 489 ASN 489 691 ?   ?   ?   B . n 
B 1 490 SER 490 692 ?   ?   ?   B . n 
B 1 491 LYS 491 693 ?   ?   ?   B . n 
B 1 492 ARG 492 694 ?   ?   ?   B . n 
B 1 493 TRP 493 695 ?   ?   ?   B . n 
B 1 494 ASN 494 696 ?   ?   ?   B . n 
B 1 495 PRO 495 697 ?   ?   ?   B . n 
B 1 496 GLU 496 698 ?   ?   ?   B . n 
B 1 497 ILE 497 699 ?   ?   ?   B . n 
B 1 498 GLN 498 700 ?   ?   ?   B . n 
B 1 499 TYR 499 701 ?   ?   ?   B . n 
B 1 500 THR 500 702 ?   ?   ?   B . n 
B 1 501 SER 501 703 ?   ?   ?   B . n 
B 1 502 ASN 502 704 ?   ?   ?   B . n 
B 1 503 TYR 503 705 ?   ?   ?   B . n 
B 1 504 TYR 504 706 ?   ?   ?   B . n 
B 1 505 LYS 505 707 ?   ?   ?   B . n 
B 1 506 SER 506 708 ?   ?   ?   B . n 
B 1 507 ASN 507 709 ?   ?   ?   B . n 
B 1 508 ASN 508 710 ?   ?   ?   B . n 
B 1 509 VAL 509 711 ?   ?   ?   B . n 
B 1 510 GLU 510 712 ?   ?   ?   B . n 
B 1 511 PHE 511 713 ?   ?   ?   B . n 
B 1 512 ALA 512 714 ?   ?   ?   B . n 
B 1 513 VAL 513 715 ?   ?   ?   B . n 
B 1 514 ASN 514 716 ?   ?   ?   B . n 
B 1 515 THR 515 717 ?   ?   ?   B . n 
B 1 516 GLU 516 718 ?   ?   ?   B . n 
B 1 517 GLY 517 719 ?   ?   ?   B . n 
B 1 518 VAL 518 720 ?   ?   ?   B . n 
B 1 519 TYR 519 721 ?   ?   ?   B . n 
B 1 520 SER 520 722 ?   ?   ?   B . n 
B 1 521 GLU 521 723 ?   ?   ?   B . n 
B 1 522 PRO 522 724 ?   ?   ?   B . n 
B 1 523 ARG 523 725 ?   ?   ?   B . n 
B 1 524 PRO 524 726 ?   ?   ?   B . n 
B 1 525 ILE 525 727 ?   ?   ?   B . n 
B 1 526 GLY 526 728 ?   ?   ?   B . n 
B 1 527 THR 527 729 ?   ?   ?   B . n 
B 1 528 ARG 528 730 ?   ?   ?   B . n 
B 1 529 TYR 529 731 ?   ?   ?   B . n 
B 1 530 LEU 530 732 ?   ?   ?   B . n 
B 1 531 THR 531 733 ?   ?   ?   B . n 
B 1 532 ARG 532 734 ?   ?   ?   B . n 
B 1 533 ASN 533 735 ?   ?   ?   B . n 
B 1 534 LEU 534 736 ?   ?   ?   B . n 
C 1 1   MET 1   203 ?   ?   ?   C . n 
C 1 2   ALA 2   204 ?   ?   ?   C . n 
C 1 3   SER 3   205 ?   ?   ?   C . n 
C 1 4   GLY 4   206 ?   ?   ?   C . n 
C 1 5   GLY 5   207 ?   ?   ?   C . n 
C 1 6   GLY 6   208 ?   ?   ?   C . n 
C 1 7   ALA 7   209 ?   ?   ?   C . n 
C 1 8   PRO 8   210 ?   ?   ?   C . n 
C 1 9   VAL 9   211 ?   ?   ?   C . n 
C 1 10  ALA 10  212 ?   ?   ?   C . n 
C 1 11  ASP 11  213 ?   ?   ?   C . n 
C 1 12  ASN 12  214 ?   ?   ?   C . n 
C 1 13  ASN 13  215 ?   ?   ?   C . n 
C 1 14  GLU 14  216 ?   ?   ?   C . n 
C 1 15  GLY 15  217 ?   ?   ?   C . n 
C 1 16  ALA 16  218 ?   ?   ?   C . n 
C 1 17  ASP 17  219 219 ASP ASP C . n 
C 1 18  GLY 18  220 220 GLY GLY C . n 
C 1 19  VAL 19  221 221 VAL VAL C . n 
C 1 20  GLY 20  222 222 GLY GLY C . n 
C 1 21  SER 21  223 223 SER SER C . n 
C 1 22  SER 22  224 224 SER SER C . n 
C 1 23  SER 23  225 225 SER SER C . n 
C 1 24  GLY 24  226 226 GLY GLY C . n 
C 1 25  ASN 25  227 227 ASN ASN C . n 
C 1 26  TRP 26  228 228 TRP TRP C . n 
C 1 27  HIS 27  229 229 HIS HIS C . n 
C 1 28  CYS 28  230 230 CYS CYS C . n 
C 1 29  ASP 29  231 231 ASP ASP C . n 
C 1 30  SER 30  232 232 SER SER C . n 
C 1 31  GLN 31  233 233 GLN GLN C . n 
C 1 32  TRP 32  234 234 TRP TRP C . n 
C 1 33  LEU 33  235 235 LEU LEU C . n 
C 1 34  GLY 34  236 236 GLY GLY C . n 
C 1 35  ASP 35  237 237 ASP ASP C . n 
C 1 36  ARG 36  238 238 ARG ARG C . n 
C 1 37  VAL 37  239 239 VAL VAL C . n 
C 1 38  ILE 38  240 240 ILE ILE C . n 
C 1 39  THR 39  241 241 THR THR C . n 
C 1 40  THR 40  242 242 THR THR C . n 
C 1 41  SER 41  243 243 SER SER C . n 
C 1 42  THR 42  244 244 THR THR C . n 
C 1 43  ARG 43  245 245 ARG ARG C . n 
C 1 44  THR 44  246 246 THR THR C . n 
C 1 45  TRP 45  247 247 TRP TRP C . n 
C 1 46  ALA 46  248 248 ALA ALA C . n 
C 1 47  LEU 47  249 249 LEU LEU C . n 
C 1 48  PRO 48  250 250 PRO PRO C . n 
C 1 49  THR 49  251 251 THR THR C . n 
C 1 50  TYR 50  252 252 TYR TYR C . n 
C 1 51  ASN 51  253 253 ASN ASN C . n 
C 1 52  ASN 52  254 254 ASN ASN C . n 
C 1 53  HIS 53  255 255 HIS HIS C . n 
C 1 54  LEU 54  256 256 LEU LEU C . n 
C 1 55  TYR 55  257 257 TYR TYR C . n 
C 1 56  LYS 56  258 258 LYS LYS C . n 
C 1 57  GLN 57  259 259 GLN GLN C . n 
C 1 58  ILE 58  260 260 ILE ILE C . n 
C 1 59  SER 59  261 261 SER SER C . n 
C 1 60  ASN 60  262 262 ASN ASN C . n 
C 1 61  SER 61  263 263 SER SER C . n 
C 1 62  THR 62  264 264 THR THR C . n 
C 1 63  SER 63  265 265 SER SER C . n 
C 1 64  GLY 64  266 266 GLY GLY C . n 
C 1 65  GLY 65  267 267 GLY GLY C . n 
C 1 66  SER 66  268 268 SER SER C . n 
C 1 67  SER 67  269 269 SER SER C . n 
C 1 68  ASN 68  270 270 ASN ASN C . n 
C 1 69  ASP 69  271 271 ASP ASP C . n 
C 1 70  ASN 70  272 272 ASN ASN C . n 
C 1 71  ALA 71  273 273 ALA ALA C . n 
C 1 72  TYR 72  274 274 TYR TYR C . n 
C 1 73  PHE 73  275 275 PHE PHE C . n 
C 1 74  GLY 74  276 276 GLY GLY C . n 
C 1 75  TYR 75  277 277 TYR TYR C . n 
C 1 76  SER 76  278 278 SER SER C . n 
C 1 77  THR 77  279 279 THR THR C . n 
C 1 78  PRO 78  280 280 PRO PRO C . n 
C 1 79  TRP 79  281 281 TRP TRP C . n 
C 1 80  GLY 80  282 282 GLY GLY C . n 
C 1 81  TYR 81  283 283 TYR TYR C . n 
C 1 82  PHE 82  284 284 PHE PHE C . n 
C 1 83  ASP 83  285 285 ASP ASP C . n 
C 1 84  PHE 84  286 286 PHE PHE C . n 
C 1 85  ASN 85  287 287 ASN ASN C . n 
C 1 86  ARG 86  288 288 ARG ARG C . n 
C 1 87  PHE 87  289 289 PHE PHE C . n 
C 1 88  HIS 88  290 290 HIS HIS C . n 
C 1 89  CYS 89  291 291 CYS CYS C . n 
C 1 90  HIS 90  292 292 HIS HIS C . n 
C 1 91  PHE 91  293 293 PHE PHE C . n 
C 1 92  SER 92  294 294 SER SER C . n 
C 1 93  PRO 93  295 295 PRO PRO C . n 
C 1 94  ARG 94  296 296 ARG ARG C . n 
C 1 95  ASP 95  297 297 ASP ASP C . n 
C 1 96  TRP 96  298 298 TRP TRP C . n 
C 1 97  GLN 97  299 299 GLN GLN C . n 
C 1 98  ARG 98  300 300 ARG ARG C . n 
C 1 99  LEU 99  301 301 LEU LEU C . n 
C 1 100 ILE 100 302 302 ILE ILE C . n 
C 1 101 ASN 101 303 303 ASN ASN C . n 
C 1 102 ASN 102 304 304 ASN ASN C . n 
C 1 103 ASN 103 305 305 ASN ASN C . n 
C 1 104 TRP 104 306 306 TRP TRP C . n 
C 1 105 GLY 105 307 307 GLY GLY C . n 
C 1 106 PHE 106 308 308 PHE PHE C . n 
C 1 107 ARG 107 309 309 ARG ARG C . n 
C 1 108 PRO 108 310 310 PRO PRO C . n 
C 1 109 LYS 109 311 311 LYS LYS C . n 
C 1 110 ARG 110 312 312 ARG ARG C . n 
C 1 111 LEU 111 313 313 LEU LEU C . n 
C 1 112 ASN 112 314 314 ASN ASN C . n 
C 1 113 PHE 113 315 315 PHE PHE C . n 
C 1 114 LYS 114 316 316 LYS LYS C . n 
C 1 115 LEU 115 317 317 LEU LEU C . n 
C 1 116 PHE 116 318 318 PHE PHE C . n 
C 1 117 ASN 117 319 319 ASN ASN C . n 
C 1 118 ILE 118 320 320 ILE ILE C . n 
C 1 119 GLN 119 321 321 GLN GLN C . n 
C 1 120 VAL 120 322 322 VAL VAL C . n 
C 1 121 LYS 121 323 323 LYS LYS C . n 
C 1 122 GLU 122 324 324 GLU GLU C . n 
C 1 123 VAL 123 325 325 VAL VAL C . n 
C 1 124 THR 124 326 326 THR THR C . n 
C 1 125 ASP 125 327 327 ASP ASP C . n 
C 1 126 ASN 126 328 328 ASN ASN C . n 
C 1 127 ASN 127 329 329 ASN ASN C . n 
C 1 128 GLY 128 330 330 GLY GLY C . n 
C 1 129 VAL 129 331 331 VAL VAL C . n 
C 1 130 LYS 130 332 332 LYS LYS C . n 
C 1 131 THR 131 333 333 THR THR C . n 
C 1 132 ILE 132 334 334 ILE ILE C . n 
C 1 133 ALA 133 335 335 ALA ALA C . n 
C 1 134 ASN 134 336 336 ASN ASN C . n 
C 1 135 ASN 135 337 337 ASN ASN C . n 
C 1 136 LEU 136 338 338 LEU LEU C . n 
C 1 137 THR 137 339 339 THR THR C . n 
C 1 138 SER 138 340 340 SER SER C . n 
C 1 139 THR 139 341 341 THR THR C . n 
C 1 140 VAL 140 342 342 VAL VAL C . n 
C 1 141 GLN 141 343 343 GLN GLN C . n 
C 1 142 VAL 142 344 344 VAL VAL C . n 
C 1 143 PHE 143 345 345 PHE PHE C . n 
C 1 144 THR 144 346 346 THR THR C . n 
C 1 145 ASP 145 347 347 ASP ASP C . n 
C 1 146 SER 146 348 348 SER SER C . n 
C 1 147 ASP 147 349 349 ASP ASP C . n 
C 1 148 TYR 148 350 350 TYR TYR C . n 
C 1 149 GLN 149 351 351 GLN GLN C . n 
C 1 150 LEU 150 352 352 LEU LEU C . n 
C 1 151 PRO 151 353 353 PRO PRO C . n 
C 1 152 TYR 152 354 354 TYR TYR C . n 
C 1 153 VAL 153 355 355 VAL VAL C . n 
C 1 154 LEU 154 356 356 LEU LEU C . n 
C 1 155 GLY 155 357 357 GLY GLY C . n 
C 1 156 SER 156 358 358 SER SER C . n 
C 1 157 ALA 157 359 359 ALA ALA C . n 
C 1 158 HIS 158 360 360 HIS HIS C . n 
C 1 159 GLU 159 361 361 GLU GLU C . n 
C 1 160 GLY 160 362 362 GLY GLY C . n 
C 1 161 CYS 161 363 363 CYS CYS C . n 
C 1 162 LEU 162 364 364 LEU LEU C . n 
C 1 163 PRO 163 365 365 PRO PRO C . n 
C 1 164 PRO 164 366 366 PRO PRO C . n 
C 1 165 PHE 165 367 367 PHE PHE C . n 
C 1 166 PRO 166 368 368 PRO PRO C . n 
C 1 167 ALA 167 369 369 ALA ALA C . n 
C 1 168 ASP 168 370 370 ASP ASP C . n 
C 1 169 VAL 169 371 371 VAL VAL C . n 
C 1 170 PHE 170 372 372 PHE PHE C . n 
C 1 171 MET 171 373 373 MET MET C . n 
C 1 172 ILE 172 374 374 ILE ILE C . n 
C 1 173 PRO 173 375 375 PRO PRO C . n 
C 1 174 GLN 174 376 376 GLN GLN C . n 
C 1 175 TYR 175 377 377 TYR TYR C . n 
C 1 176 GLY 176 378 378 GLY GLY C . n 
C 1 177 TYR 177 379 379 TYR TYR C . n 
C 1 178 LEU 178 380 380 LEU LEU C . n 
C 1 179 THR 179 381 381 THR THR C . n 
C 1 180 LEU 180 382 382 LEU LEU C . n 
C 1 181 ASN 181 383 383 ASN ASN C . n 
C 1 182 ASP 182 384 384 ASP ASP C . n 
C 1 183 GLY 183 385 385 GLY GLY C . n 
C 1 184 SER 184 386 386 SER SER C . n 
C 1 185 GLN 185 387 387 GLN GLN C . n 
C 1 186 ALA 186 388 388 ALA ALA C . n 
C 1 187 VAL 187 389 389 VAL VAL C . n 
C 1 188 GLY 188 390 390 GLY GLY C . n 
C 1 189 ARG 189 391 391 ARG ARG C . n 
C 1 190 SER 190 392 392 SER SER C . n 
C 1 191 SER 191 393 393 SER SER C . n 
C 1 192 PHE 192 394 394 PHE PHE C . n 
C 1 193 TYR 193 395 395 TYR TYR C . n 
C 1 194 CYS 194 396 396 CYS CYS C . n 
C 1 195 LEU 195 397 397 LEU LEU C . n 
C 1 196 GLU 196 398 398 GLU GLU C . n 
C 1 197 TYR 197 399 399 TYR TYR C . n 
C 1 198 PHE 198 400 400 PHE PHE C . n 
C 1 199 PRO 199 401 401 PRO PRO C . n 
C 1 200 SER 200 402 402 SER SER C . n 
C 1 201 GLN 201 403 403 GLN GLN C . n 
C 1 202 MET 202 404 404 MET MET C . n 
C 1 203 LEU 203 405 405 LEU LEU C . n 
C 1 204 ARG 204 406 406 ARG ARG C . n 
C 1 205 THR 205 407 407 THR THR C . n 
C 1 206 GLY 206 408 408 GLY GLY C . n 
C 1 207 ASN 207 409 409 ASN ASN C . n 
C 1 208 ASN 208 410 410 ASN ASN C . n 
C 1 209 PHE 209 411 411 PHE PHE C . n 
C 1 210 GLN 210 412 412 GLN GLN C . n 
C 1 211 PHE 211 413 413 PHE PHE C . n 
C 1 212 SER 212 414 414 SER SER C . n 
C 1 213 TYR 213 415 415 TYR TYR C . n 
C 1 214 GLU 214 416 416 GLU GLU C . n 
C 1 215 PHE 215 417 417 PHE PHE C . n 
C 1 216 GLU 216 418 418 GLU GLU C . n 
C 1 217 ASN 217 419 419 ASN ASN C . n 
C 1 218 VAL 218 420 420 VAL VAL C . n 
C 1 219 PRO 219 421 421 PRO PRO C . n 
C 1 220 PHE 220 422 422 PHE PHE C . n 
C 1 221 HIS 221 423 423 HIS HIS C . n 
C 1 222 SER 222 424 424 SER SER C . n 
C 1 223 SER 223 425 425 SER SER C . n 
C 1 224 TYR 224 426 426 TYR TYR C . n 
C 1 225 ALA 225 427 427 ALA ALA C . n 
C 1 226 HIS 226 428 428 HIS HIS C . n 
C 1 227 SER 227 429 429 SER SER C . n 
C 1 228 GLN 228 430 430 GLN GLN C . n 
C 1 229 SER 229 431 431 SER SER C . n 
C 1 230 LEU 230 432 432 LEU LEU C . n 
C 1 231 ASP 231 433 433 ASP ASP C . n 
C 1 232 ARG 232 434 434 ARG ARG C . n 
C 1 233 LEU 233 435 435 LEU LEU C . n 
C 1 234 MET 234 436 436 MET MET C . n 
C 1 235 ASN 235 437 437 ASN ASN C . n 
C 1 236 PRO 236 438 438 PRO PRO C . n 
C 1 237 LEU 237 439 439 LEU LEU C . n 
C 1 238 ILE 238 440 440 ILE ILE C . n 
C 1 239 ASP 239 441 441 ASP ASP C . n 
C 1 240 GLN 240 442 442 GLN GLN C . n 
C 1 241 TYR 241 443 443 TYR TYR C . n 
C 1 242 LEU 242 444 444 LEU LEU C . n 
C 1 243 TYR 243 445 445 TYR TYR C . n 
C 1 244 TYR 244 446 446 TYR TYR C . n 
C 1 245 LEU 245 447 447 LEU LEU C . n 
C 1 246 SER 246 448 448 SER SER C . n 
C 1 247 LYS 247 449 449 LYS LYS C . n 
C 1 248 THR 248 450 450 THR THR C . n 
C 1 249 ILE 249 451 451 ILE ILE C . n 
C 1 250 ASN 250 452 452 ASN ASN C . n 
C 1 251 GLY 251 453 453 GLY GLY C . n 
C 1 252 SER 252 454 454 SER SER C . n 
C 1 253 GLY 253 455 455 GLY GLY C . n 
C 1 254 GLN 254 456 456 GLN GLN C . n 
C 1 255 ASN 255 457 457 ASN ASN C . n 
C 1 256 GLN 256 458 458 GLN GLN C . n 
C 1 257 GLN 257 459 459 GLN GLN C . n 
C 1 258 THR 258 460 460 THR THR C . n 
C 1 259 LEU 259 461 461 LEU LEU C . n 
C 1 260 LYS 260 462 462 LYS LYS C . n 
C 1 261 PHE 261 463 463 PHE PHE C . n 
C 1 262 SER 262 464 464 SER SER C . n 
C 1 263 VAL 263 465 465 VAL VAL C . n 
C 1 264 ALA 264 466 466 ALA ALA C . n 
C 1 265 GLY 265 467 467 GLY GLY C . n 
C 1 266 PRO 266 468 468 PRO PRO C . n 
C 1 267 SER 267 469 469 SER SER C . n 
C 1 268 ASN 268 470 470 ASN ASN C . n 
C 1 269 MET 269 471 471 MET MET C . n 
C 1 270 ALA 270 472 472 ALA ALA C . n 
C 1 271 VAL 271 473 473 VAL VAL C . n 
C 1 272 GLN 272 474 474 GLN GLN C . n 
C 1 273 GLY 273 475 475 GLY GLY C . n 
C 1 274 ARG 274 476 476 ARG ARG C . n 
C 1 275 ASN 275 477 477 ASN ASN C . n 
C 1 276 TYR 276 478 478 TYR TYR C . n 
C 1 277 ILE 277 479 479 ILE ILE C . n 
C 1 278 PRO 278 480 480 PRO PRO C . n 
C 1 279 GLY 279 481 481 GLY GLY C . n 
C 1 280 PRO 280 482 482 PRO PRO C . n 
C 1 281 SER 281 483 483 SER SER C . n 
C 1 282 TYR 282 484 484 TYR TYR C . n 
C 1 283 ARG 283 485 485 ARG ARG C . n 
C 1 284 GLN 284 486 486 GLN GLN C . n 
C 1 285 GLN 285 487 487 GLN GLN C . n 
C 1 286 ARG 286 488 488 ARG ARG C . n 
C 1 287 VAL 287 489 489 VAL VAL C . n 
C 1 288 SER 288 490 490 SER SER C . n 
C 1 289 THR 289 491 491 THR THR C . n 
C 1 290 THR 290 492 492 THR THR C . n 
C 1 291 VAL 291 493 493 VAL VAL C . n 
C 1 292 THR 292 494 494 THR THR C . n 
C 1 293 GLN 293 495 495 GLN GLN C . n 
C 1 294 ASN 294 496 496 ASN ASN C . n 
C 1 295 ASN 295 497 497 ASN ASN C . n 
C 1 296 ASN 296 498 498 ASN ASN C . n 
C 1 297 SER 297 499 499 SER SER C . n 
C 1 298 GLU 298 500 500 GLU GLU C . n 
C 1 299 PHE 299 501 501 PHE PHE C . n 
C 1 300 ALA 300 502 502 ALA ALA C . n 
C 1 301 TRP 301 503 503 TRP TRP C . n 
C 1 302 PRO 302 504 504 PRO PRO C . n 
C 1 303 GLY 303 505 505 GLY GLY C . n 
C 1 304 ALA 304 506 506 ALA ALA C . n 
C 1 305 SER 305 507 507 SER SER C . n 
C 1 306 SER 306 508 508 SER SER C . n 
C 1 307 TRP 307 509 509 TRP TRP C . n 
C 1 308 ALA 308 510 510 ALA ALA C . n 
C 1 309 LEU 309 511 511 LEU LEU C . n 
C 1 310 ASN 310 512 512 ASN ASN C . n 
C 1 311 GLY 311 513 513 GLY GLY C . n 
C 1 312 ARG 312 514 514 ARG ARG C . n 
C 1 313 ASN 313 515 515 ASN ASN C . n 
C 1 314 SER 314 516 516 SER SER C . n 
C 1 315 LEU 315 517 517 LEU LEU C . n 
C 1 316 MET 316 518 518 MET MET C . n 
C 1 317 ASN 317 519 519 ASN ASN C . n 
C 1 318 PRO 318 520 520 PRO PRO C . n 
C 1 319 GLY 319 521 521 GLY GLY C . n 
C 1 320 PRO 320 522 522 PRO PRO C . n 
C 1 321 ALA 321 523 523 ALA ALA C . n 
C 1 322 MET 322 524 524 MET MET C . n 
C 1 323 ALA 323 525 525 ALA ALA C . n 
C 1 324 SER 324 526 526 SER SER C . n 
C 1 325 HIS 325 527 527 HIS HIS C . n 
C 1 326 LYS 326 528 528 LYS LYS C . n 
C 1 327 GLU 327 529 529 GLU GLU C . n 
C 1 328 GLY 328 530 530 GLY GLY C . n 
C 1 329 GLU 329 531 531 GLU GLU C . n 
C 1 330 ASP 330 532 532 ASP ASP C . n 
C 1 331 ARG 331 533 533 ARG ARG C . n 
C 1 332 PHE 332 534 534 PHE PHE C . n 
C 1 333 PHE 333 535 535 PHE PHE C . n 
C 1 334 PRO 334 536 536 PRO PRO C . n 
C 1 335 LEU 335 537 537 LEU LEU C . n 
C 1 336 SER 336 538 538 SER SER C . n 
C 1 337 GLY 337 539 539 GLY GLY C . n 
C 1 338 SER 338 540 540 SER SER C . n 
C 1 339 LEU 339 541 541 LEU LEU C . n 
C 1 340 ILE 340 542 542 ILE ILE C . n 
C 1 341 PHE 341 543 543 PHE PHE C . n 
C 1 342 GLY 342 544 544 GLY GLY C . n 
C 1 343 LYS 343 545 545 LYS LYS C . n 
C 1 344 GLN 344 546 546 GLN GLN C . n 
C 1 345 GLY 345 547 547 GLY GLY C . n 
C 1 346 THR 346 548 548 THR THR C . n 
C 1 347 GLY 347 549 549 GLY GLY C . n 
C 1 348 ARG 348 550 550 ARG ARG C . n 
C 1 349 ASP 349 551 551 ASP ASP C . n 
C 1 350 ASN 350 552 552 ASN ASN C . n 
C 1 351 VAL 351 553 553 VAL VAL C . n 
C 1 352 ASP 352 554 554 ASP ASP C . n 
C 1 353 ALA 353 555 555 ALA ALA C . n 
C 1 354 ASP 354 556 556 ASP ASP C . n 
C 1 355 LYS 355 557 557 LYS LYS C . n 
C 1 356 VAL 356 558 558 VAL VAL C . n 
C 1 357 MET 357 559 559 MET MET C . n 
C 1 358 ILE 358 560 560 ILE ILE C . n 
C 1 359 THR 359 561 561 THR THR C . n 
C 1 360 ASN 360 562 562 ASN ASN C . n 
C 1 361 GLU 361 563 563 GLU GLU C . n 
C 1 362 GLU 362 564 564 GLU GLU C . n 
C 1 363 GLU 363 565 565 GLU GLU C . n 
C 1 364 ILE 364 566 566 ILE ILE C . n 
C 1 365 LYS 365 567 567 LYS LYS C . n 
C 1 366 THR 366 568 568 THR THR C . n 
C 1 367 THR 367 569 569 THR THR C . n 
C 1 368 ASN 368 570 570 ASN ASN C . n 
C 1 369 PRO 369 571 571 PRO PRO C . n 
C 1 370 VAL 370 572 572 VAL VAL C . n 
C 1 371 ALA 371 573 573 ALA ALA C . n 
C 1 372 THR 372 574 574 THR THR C . n 
C 1 373 GLU 373 575 575 GLU GLU C . n 
C 1 374 SER 374 576 576 SER SER C . n 
C 1 375 TYR 375 577 577 TYR TYR C . n 
C 1 376 GLY 376 578 578 GLY GLY C . n 
C 1 377 GLN 377 579 579 GLN GLN C . n 
C 1 378 VAL 378 580 580 VAL VAL C . n 
C 1 379 ALA 379 581 581 ALA ALA C . n 
C 1 380 THR 380 582 582 THR THR C . n 
C 1 381 ASN 381 583 583 ASN ASN C . n 
C 1 382 HIS 382 584 584 HIS HIS C . n 
C 1 383 GLN 383 585 585 GLN GLN C . n 
C 1 384 SER 384 586 586 SER SER C . n 
C 1 385 ALA 385 587 587 ALA ALA C . n 
C 1 386 GLN 386 588 588 GLN GLN C . n 
C 1 387 ALA 387 589 589 ALA ALA C . n 
C 1 388 GLN 388 590 590 GLN GLN C . n 
C 1 389 ALA 389 591 591 ALA ALA C . n 
C 1 390 GLN 390 592 592 GLN GLN C . n 
C 1 391 THR 391 593 593 THR THR C . n 
C 1 392 GLY 392 594 594 GLY GLY C . n 
C 1 393 TRP 393 595 595 TRP TRP C . n 
C 1 394 VAL 394 596 596 VAL VAL C . n 
C 1 395 GLN 395 597 597 GLN GLN C . n 
C 1 396 ASN 396 598 598 ASN ASN C . n 
C 1 397 GLN 397 599 599 GLN GLN C . n 
C 1 398 GLY 398 600 600 GLY GLY C . n 
C 1 399 ILE 399 601 601 ILE ILE C . n 
C 1 400 LEU 400 602 602 LEU LEU C . n 
C 1 401 PRO 401 603 603 PRO PRO C . n 
C 1 402 GLY 402 604 604 GLY GLY C . n 
C 1 403 MET 403 605 605 MET MET C . n 
C 1 404 VAL 404 606 606 VAL VAL C . n 
C 1 405 TRP 405 607 607 TRP TRP C . n 
C 1 406 GLN 406 608 608 GLN GLN C . n 
C 1 407 ASP 407 609 609 ASP ASP C . n 
C 1 408 ARG 408 610 610 ARG ARG C . n 
C 1 409 ASP 409 611 611 ASP ASP C . n 
C 1 410 VAL 410 612 612 VAL VAL C . n 
C 1 411 TYR 411 613 613 TYR TYR C . n 
C 1 412 LEU 412 614 614 LEU LEU C . n 
C 1 413 GLN 413 615 615 GLN GLN C . n 
C 1 414 GLY 414 616 616 GLY GLY C . n 
C 1 415 PRO 415 617 617 PRO PRO C . n 
C 1 416 ILE 416 618 618 ILE ILE C . n 
C 1 417 TRP 417 619 619 TRP TRP C . n 
C 1 418 ALA 418 620 620 ALA ALA C . n 
C 1 419 LYS 419 621 621 LYS LYS C . n 
C 1 420 ILE 420 622 622 ILE ILE C . n 
C 1 421 PRO 421 623 623 PRO PRO C . n 
C 1 422 HIS 422 624 624 HIS HIS C . n 
C 1 423 THR 423 625 625 THR THR C . n 
C 1 424 ASP 424 626 626 ASP ASP C . n 
C 1 425 GLY 425 627 627 GLY GLY C . n 
C 1 426 ASN 426 628 628 ASN ASN C . n 
C 1 427 PHE 427 629 629 PHE PHE C . n 
C 1 428 HIS 428 630 630 HIS HIS C . n 
C 1 429 PRO 429 631 631 PRO PRO C . n 
C 1 430 SER 430 632 632 SER SER C . n 
C 1 431 PRO 431 633 633 PRO PRO C . n 
C 1 432 LEU 432 634 634 LEU LEU C . n 
C 1 433 MET 433 635 635 MET MET C . n 
C 1 434 GLY 434 636 636 GLY GLY C . n 
C 1 435 GLY 435 637 637 GLY GLY C . n 
C 1 436 PHE 436 638 638 PHE PHE C . n 
C 1 437 GLY 437 639 639 GLY GLY C . n 
C 1 438 MET 438 640 640 MET MET C . n 
C 1 439 LYS 439 641 641 LYS LYS C . n 
C 1 440 HIS 440 642 642 HIS HIS C . n 
C 1 441 PRO 441 643 643 PRO PRO C . n 
C 1 442 PRO 442 644 644 PRO PRO C . n 
C 1 443 PRO 443 645 645 PRO PRO C . n 
C 1 444 GLN 444 646 646 GLN GLN C . n 
C 1 445 ILE 445 647 647 ILE ILE C . n 
C 1 446 LEU 446 648 648 LEU LEU C . n 
C 1 447 ILE 447 649 649 ILE ILE C . n 
C 1 448 LYS 448 650 650 LYS LYS C . n 
C 1 449 ASN 449 651 651 ASN ASN C . n 
C 1 450 THR 450 652 652 THR THR C . n 
C 1 451 PRO 451 653 653 PRO PRO C . n 
C 1 452 VAL 452 654 654 VAL VAL C . n 
C 1 453 PRO 453 655 655 PRO PRO C . n 
C 1 454 ALA 454 656 ?   ?   ?   C . n 
C 1 455 ASP 455 657 ?   ?   ?   C . n 
C 1 456 PRO 456 658 ?   ?   ?   C . n 
C 1 457 PRO 457 659 ?   ?   ?   C . n 
C 1 458 THR 458 660 ?   ?   ?   C . n 
C 1 459 ALA 459 661 ?   ?   ?   C . n 
C 1 460 PHE 460 662 ?   ?   ?   C . n 
C 1 461 ASN 461 663 ?   ?   ?   C . n 
C 1 462 LYS 462 664 ?   ?   ?   C . n 
C 1 463 ASP 463 665 ?   ?   ?   C . n 
C 1 464 LYS 464 666 ?   ?   ?   C . n 
C 1 465 LEU 465 667 667 LEU LEU C . n 
C 1 466 ASN 466 668 668 ASN ASN C . n 
C 1 467 SER 467 669 669 SER SER C . n 
C 1 468 PHE 468 670 670 PHE PHE C . n 
C 1 469 ILE 469 671 671 ILE ILE C . n 
C 1 470 THR 470 672 672 THR THR C . n 
C 1 471 GLN 471 673 673 GLN GLN C . n 
C 1 472 TYR 472 674 674 TYR TYR C . n 
C 1 473 SER 473 675 675 SER SER C . n 
C 1 474 THR 474 676 676 THR THR C . n 
C 1 475 GLY 475 677 677 GLY GLY C . n 
C 1 476 GLN 476 678 678 GLN GLN C . n 
C 1 477 VAL 477 679 679 VAL VAL C . n 
C 1 478 SER 478 680 680 SER SER C . n 
C 1 479 VAL 479 681 681 VAL VAL C . n 
C 1 480 GLU 480 682 682 GLU GLU C . n 
C 1 481 ILE 481 683 683 ILE ILE C . n 
C 1 482 GLU 482 684 684 GLU GLU C . n 
C 1 483 TRP 483 685 685 TRP TRP C . n 
C 1 484 GLU 484 686 686 GLU GLU C . n 
C 1 485 LEU 485 687 687 LEU LEU C . n 
C 1 486 GLN 486 688 688 GLN GLN C . n 
C 1 487 LYS 487 689 689 LYS LYS C . n 
C 1 488 GLU 488 690 690 GLU GLU C . n 
C 1 489 ASN 489 691 691 ASN ASN C . n 
C 1 490 SER 490 692 692 SER SER C . n 
C 1 491 LYS 491 693 693 LYS LYS C . n 
C 1 492 ARG 492 694 694 ARG ARG C . n 
C 1 493 TRP 493 695 695 TRP TRP C . n 
C 1 494 ASN 494 696 696 ASN ASN C . n 
C 1 495 PRO 495 697 697 PRO PRO C . n 
C 1 496 GLU 496 698 698 GLU GLU C . n 
C 1 497 ILE 497 699 699 ILE ILE C . n 
C 1 498 GLN 498 700 700 GLN GLN C . n 
C 1 499 TYR 499 701 701 TYR TYR C . n 
C 1 500 THR 500 702 702 THR THR C . n 
C 1 501 SER 501 703 703 SER SER C . n 
C 1 502 ASN 502 704 704 ASN ASN C . n 
C 1 503 TYR 503 705 705 TYR TYR C . n 
C 1 504 TYR 504 706 706 TYR TYR C . n 
C 1 505 LYS 505 707 707 LYS LYS C . n 
C 1 506 SER 506 708 708 SER SER C . n 
C 1 507 ASN 507 709 709 ASN ASN C . n 
C 1 508 ASN 508 710 710 ASN ASN C . n 
C 1 509 VAL 509 711 711 VAL VAL C . n 
C 1 510 GLU 510 712 712 GLU GLU C . n 
C 1 511 PHE 511 713 713 PHE PHE C . n 
C 1 512 ALA 512 714 714 ALA ALA C . n 
C 1 513 VAL 513 715 715 VAL VAL C . n 
C 1 514 ASN 514 716 716 ASN ASN C . n 
C 1 515 THR 515 717 717 THR THR C . n 
C 1 516 GLU 516 718 718 GLU GLU C . n 
C 1 517 GLY 517 719 719 GLY GLY C . n 
C 1 518 VAL 518 720 720 VAL VAL C . n 
C 1 519 TYR 519 721 721 TYR TYR C . n 
C 1 520 SER 520 722 722 SER SER C . n 
C 1 521 GLU 521 723 723 GLU GLU C . n 
C 1 522 PRO 522 724 724 PRO PRO C . n 
C 1 523 ARG 523 725 725 ARG ARG C . n 
C 1 524 PRO 524 726 726 PRO PRO C . n 
C 1 525 ILE 525 727 727 ILE ILE C . n 
C 1 526 GLY 526 728 728 GLY GLY C . n 
C 1 527 THR 527 729 729 THR THR C . n 
C 1 528 ARG 528 730 730 ARG ARG C . n 
C 1 529 TYR 529 731 731 TYR TYR C . n 
C 1 530 LEU 530 732 732 LEU LEU C . n 
C 1 531 THR 531 733 733 THR THR C . n 
C 1 532 ARG 532 734 734 ARG ARG C . n 
C 1 533 ASN 533 735 735 ASN ASN C . n 
C 1 534 LEU 534 736 736 LEU LEU C . n 
D 1 1   MET 1   203 ?   ?   ?   D . n 
D 1 2   ALA 2   204 ?   ?   ?   D . n 
D 1 3   SER 3   205 ?   ?   ?   D . n 
D 1 4   GLY 4   206 ?   ?   ?   D . n 
D 1 5   GLY 5   207 ?   ?   ?   D . n 
D 1 6   GLY 6   208 ?   ?   ?   D . n 
D 1 7   ALA 7   209 ?   ?   ?   D . n 
D 1 8   PRO 8   210 ?   ?   ?   D . n 
D 1 9   VAL 9   211 ?   ?   ?   D . n 
D 1 10  ALA 10  212 ?   ?   ?   D . n 
D 1 11  ASP 11  213 ?   ?   ?   D . n 
D 1 12  ASN 12  214 ?   ?   ?   D . n 
D 1 13  ASN 13  215 ?   ?   ?   D . n 
D 1 14  GLU 14  216 ?   ?   ?   D . n 
D 1 15  GLY 15  217 ?   ?   ?   D . n 
D 1 16  ALA 16  218 ?   ?   ?   D . n 
D 1 17  ASP 17  219 219 ASP ASP D . n 
D 1 18  GLY 18  220 220 GLY GLY D . n 
D 1 19  VAL 19  221 221 VAL VAL D . n 
D 1 20  GLY 20  222 222 GLY GLY D . n 
D 1 21  SER 21  223 223 SER SER D . n 
D 1 22  SER 22  224 224 SER SER D . n 
D 1 23  SER 23  225 225 SER SER D . n 
D 1 24  GLY 24  226 226 GLY GLY D . n 
D 1 25  ASN 25  227 227 ASN ASN D . n 
D 1 26  TRP 26  228 228 TRP TRP D . n 
D 1 27  HIS 27  229 229 HIS HIS D . n 
D 1 28  CYS 28  230 230 CYS CYS D . n 
D 1 29  ASP 29  231 231 ASP ASP D . n 
D 1 30  SER 30  232 232 SER SER D . n 
D 1 31  GLN 31  233 233 GLN GLN D . n 
D 1 32  TRP 32  234 234 TRP TRP D . n 
D 1 33  LEU 33  235 235 LEU LEU D . n 
D 1 34  GLY 34  236 236 GLY GLY D . n 
D 1 35  ASP 35  237 237 ASP ASP D . n 
D 1 36  ARG 36  238 238 ARG ARG D . n 
D 1 37  VAL 37  239 239 VAL VAL D . n 
D 1 38  ILE 38  240 240 ILE ILE D . n 
D 1 39  THR 39  241 241 THR THR D . n 
D 1 40  THR 40  242 242 THR THR D . n 
D 1 41  SER 41  243 243 SER SER D . n 
D 1 42  THR 42  244 244 THR THR D . n 
D 1 43  ARG 43  245 245 ARG ARG D . n 
D 1 44  THR 44  246 246 THR THR D . n 
D 1 45  TRP 45  247 247 TRP TRP D . n 
D 1 46  ALA 46  248 248 ALA ALA D . n 
D 1 47  LEU 47  249 249 LEU LEU D . n 
D 1 48  PRO 48  250 250 PRO PRO D . n 
D 1 49  THR 49  251 251 THR THR D . n 
D 1 50  TYR 50  252 252 TYR TYR D . n 
D 1 51  ASN 51  253 253 ASN ASN D . n 
D 1 52  ASN 52  254 254 ASN ASN D . n 
D 1 53  HIS 53  255 255 HIS HIS D . n 
D 1 54  LEU 54  256 256 LEU LEU D . n 
D 1 55  TYR 55  257 257 TYR TYR D . n 
D 1 56  LYS 56  258 258 LYS LYS D . n 
D 1 57  GLN 57  259 259 GLN GLN D . n 
D 1 58  ILE 58  260 260 ILE ILE D . n 
D 1 59  SER 59  261 261 SER SER D . n 
D 1 60  ASN 60  262 262 ASN ASN D . n 
D 1 61  SER 61  263 263 SER SER D . n 
D 1 62  THR 62  264 264 THR THR D . n 
D 1 63  SER 63  265 265 SER SER D . n 
D 1 64  GLY 64  266 266 GLY GLY D . n 
D 1 65  GLY 65  267 267 GLY GLY D . n 
D 1 66  SER 66  268 268 SER SER D . n 
D 1 67  SER 67  269 269 SER SER D . n 
D 1 68  ASN 68  270 270 ASN ASN D . n 
D 1 69  ASP 69  271 271 ASP ASP D . n 
D 1 70  ASN 70  272 272 ASN ASN D . n 
D 1 71  ALA 71  273 273 ALA ALA D . n 
D 1 72  TYR 72  274 274 TYR TYR D . n 
D 1 73  PHE 73  275 275 PHE PHE D . n 
D 1 74  GLY 74  276 276 GLY GLY D . n 
D 1 75  TYR 75  277 277 TYR TYR D . n 
D 1 76  SER 76  278 278 SER SER D . n 
D 1 77  THR 77  279 279 THR THR D . n 
D 1 78  PRO 78  280 280 PRO PRO D . n 
D 1 79  TRP 79  281 281 TRP TRP D . n 
D 1 80  GLY 80  282 282 GLY GLY D . n 
D 1 81  TYR 81  283 283 TYR TYR D . n 
D 1 82  PHE 82  284 284 PHE PHE D . n 
D 1 83  ASP 83  285 285 ASP ASP D . n 
D 1 84  PHE 84  286 286 PHE PHE D . n 
D 1 85  ASN 85  287 287 ASN ASN D . n 
D 1 86  ARG 86  288 288 ARG ARG D . n 
D 1 87  PHE 87  289 289 PHE PHE D . n 
D 1 88  HIS 88  290 290 HIS HIS D . n 
D 1 89  CYS 89  291 291 CYS CYS D . n 
D 1 90  HIS 90  292 292 HIS HIS D . n 
D 1 91  PHE 91  293 293 PHE PHE D . n 
D 1 92  SER 92  294 294 SER SER D . n 
D 1 93  PRO 93  295 295 PRO PRO D . n 
D 1 94  ARG 94  296 296 ARG ARG D . n 
D 1 95  ASP 95  297 297 ASP ASP D . n 
D 1 96  TRP 96  298 298 TRP TRP D . n 
D 1 97  GLN 97  299 299 GLN GLN D . n 
D 1 98  ARG 98  300 300 ARG ARG D . n 
D 1 99  LEU 99  301 301 LEU LEU D . n 
D 1 100 ILE 100 302 302 ILE ILE D . n 
D 1 101 ASN 101 303 303 ASN ASN D . n 
D 1 102 ASN 102 304 304 ASN ASN D . n 
D 1 103 ASN 103 305 305 ASN ASN D . n 
D 1 104 TRP 104 306 306 TRP TRP D . n 
D 1 105 GLY 105 307 307 GLY GLY D . n 
D 1 106 PHE 106 308 308 PHE PHE D . n 
D 1 107 ARG 107 309 309 ARG ARG D . n 
D 1 108 PRO 108 310 310 PRO PRO D . n 
D 1 109 LYS 109 311 311 LYS LYS D . n 
D 1 110 ARG 110 312 312 ARG ARG D . n 
D 1 111 LEU 111 313 313 LEU LEU D . n 
D 1 112 ASN 112 314 314 ASN ASN D . n 
D 1 113 PHE 113 315 315 PHE PHE D . n 
D 1 114 LYS 114 316 316 LYS LYS D . n 
D 1 115 LEU 115 317 317 LEU LEU D . n 
D 1 116 PHE 116 318 318 PHE PHE D . n 
D 1 117 ASN 117 319 319 ASN ASN D . n 
D 1 118 ILE 118 320 320 ILE ILE D . n 
D 1 119 GLN 119 321 321 GLN GLN D . n 
D 1 120 VAL 120 322 322 VAL VAL D . n 
D 1 121 LYS 121 323 323 LYS LYS D . n 
D 1 122 GLU 122 324 324 GLU GLU D . n 
D 1 123 VAL 123 325 325 VAL VAL D . n 
D 1 124 THR 124 326 326 THR THR D . n 
D 1 125 ASP 125 327 327 ASP ASP D . n 
D 1 126 ASN 126 328 328 ASN ASN D . n 
D 1 127 ASN 127 329 329 ASN ASN D . n 
D 1 128 GLY 128 330 330 GLY GLY D . n 
D 1 129 VAL 129 331 331 VAL VAL D . n 
D 1 130 LYS 130 332 332 LYS LYS D . n 
D 1 131 THR 131 333 333 THR THR D . n 
D 1 132 ILE 132 334 334 ILE ILE D . n 
D 1 133 ALA 133 335 335 ALA ALA D . n 
D 1 134 ASN 134 336 336 ASN ASN D . n 
D 1 135 ASN 135 337 337 ASN ASN D . n 
D 1 136 LEU 136 338 338 LEU LEU D . n 
D 1 137 THR 137 339 339 THR THR D . n 
D 1 138 SER 138 340 340 SER SER D . n 
D 1 139 THR 139 341 341 THR THR D . n 
D 1 140 VAL 140 342 342 VAL VAL D . n 
D 1 141 GLN 141 343 343 GLN GLN D . n 
D 1 142 VAL 142 344 344 VAL VAL D . n 
D 1 143 PHE 143 345 345 PHE PHE D . n 
D 1 144 THR 144 346 346 THR THR D . n 
D 1 145 ASP 145 347 347 ASP ASP D . n 
D 1 146 SER 146 348 348 SER SER D . n 
D 1 147 ASP 147 349 349 ASP ASP D . n 
D 1 148 TYR 148 350 350 TYR TYR D . n 
D 1 149 GLN 149 351 351 GLN GLN D . n 
D 1 150 LEU 150 352 352 LEU LEU D . n 
D 1 151 PRO 151 353 353 PRO PRO D . n 
D 1 152 TYR 152 354 354 TYR TYR D . n 
D 1 153 VAL 153 355 355 VAL VAL D . n 
D 1 154 LEU 154 356 356 LEU LEU D . n 
D 1 155 GLY 155 357 357 GLY GLY D . n 
D 1 156 SER 156 358 358 SER SER D . n 
D 1 157 ALA 157 359 359 ALA ALA D . n 
D 1 158 HIS 158 360 360 HIS HIS D . n 
D 1 159 GLU 159 361 361 GLU GLU D . n 
D 1 160 GLY 160 362 362 GLY GLY D . n 
D 1 161 CYS 161 363 363 CYS CYS D . n 
D 1 162 LEU 162 364 364 LEU LEU D . n 
D 1 163 PRO 163 365 365 PRO PRO D . n 
D 1 164 PRO 164 366 366 PRO PRO D . n 
D 1 165 PHE 165 367 367 PHE PHE D . n 
D 1 166 PRO 166 368 368 PRO PRO D . n 
D 1 167 ALA 167 369 369 ALA ALA D . n 
D 1 168 ASP 168 370 370 ASP ASP D . n 
D 1 169 VAL 169 371 371 VAL VAL D . n 
D 1 170 PHE 170 372 372 PHE PHE D . n 
D 1 171 MET 171 373 373 MET MET D . n 
D 1 172 ILE 172 374 374 ILE ILE D . n 
D 1 173 PRO 173 375 375 PRO PRO D . n 
D 1 174 GLN 174 376 376 GLN GLN D . n 
D 1 175 TYR 175 377 377 TYR TYR D . n 
D 1 176 GLY 176 378 378 GLY GLY D . n 
D 1 177 TYR 177 379 379 TYR TYR D . n 
D 1 178 LEU 178 380 380 LEU LEU D . n 
D 1 179 THR 179 381 381 THR THR D . n 
D 1 180 LEU 180 382 382 LEU LEU D . n 
D 1 181 ASN 181 383 383 ASN ASN D . n 
D 1 182 ASP 182 384 384 ASP ASP D . n 
D 1 183 GLY 183 385 385 GLY GLY D . n 
D 1 184 SER 184 386 386 SER SER D . n 
D 1 185 GLN 185 387 387 GLN GLN D . n 
D 1 186 ALA 186 388 388 ALA ALA D . n 
D 1 187 VAL 187 389 389 VAL VAL D . n 
D 1 188 GLY 188 390 390 GLY GLY D . n 
D 1 189 ARG 189 391 391 ARG ARG D . n 
D 1 190 SER 190 392 392 SER SER D . n 
D 1 191 SER 191 393 393 SER SER D . n 
D 1 192 PHE 192 394 394 PHE PHE D . n 
D 1 193 TYR 193 395 395 TYR TYR D . n 
D 1 194 CYS 194 396 396 CYS CYS D . n 
D 1 195 LEU 195 397 397 LEU LEU D . n 
D 1 196 GLU 196 398 398 GLU GLU D . n 
D 1 197 TYR 197 399 399 TYR TYR D . n 
D 1 198 PHE 198 400 400 PHE PHE D . n 
D 1 199 PRO 199 401 401 PRO PRO D . n 
D 1 200 SER 200 402 402 SER SER D . n 
D 1 201 GLN 201 403 403 GLN GLN D . n 
D 1 202 MET 202 404 404 MET MET D . n 
D 1 203 LEU 203 405 405 LEU LEU D . n 
D 1 204 ARG 204 406 406 ARG ARG D . n 
D 1 205 THR 205 407 407 THR THR D . n 
D 1 206 GLY 206 408 408 GLY GLY D . n 
D 1 207 ASN 207 409 409 ASN ASN D . n 
D 1 208 ASN 208 410 410 ASN ASN D . n 
D 1 209 PHE 209 411 411 PHE PHE D . n 
D 1 210 GLN 210 412 412 GLN GLN D . n 
D 1 211 PHE 211 413 413 PHE PHE D . n 
D 1 212 SER 212 414 414 SER SER D . n 
D 1 213 TYR 213 415 415 TYR TYR D . n 
D 1 214 GLU 214 416 416 GLU GLU D . n 
D 1 215 PHE 215 417 417 PHE PHE D . n 
D 1 216 GLU 216 418 418 GLU GLU D . n 
D 1 217 ASN 217 419 419 ASN ASN D . n 
D 1 218 VAL 218 420 420 VAL VAL D . n 
D 1 219 PRO 219 421 421 PRO PRO D . n 
D 1 220 PHE 220 422 422 PHE PHE D . n 
D 1 221 HIS 221 423 423 HIS HIS D . n 
D 1 222 SER 222 424 424 SER SER D . n 
D 1 223 SER 223 425 425 SER SER D . n 
D 1 224 TYR 224 426 426 TYR TYR D . n 
D 1 225 ALA 225 427 427 ALA ALA D . n 
D 1 226 HIS 226 428 428 HIS HIS D . n 
D 1 227 SER 227 429 429 SER SER D . n 
D 1 228 GLN 228 430 430 GLN GLN D . n 
D 1 229 SER 229 431 431 SER SER D . n 
D 1 230 LEU 230 432 432 LEU LEU D . n 
D 1 231 ASP 231 433 433 ASP ASP D . n 
D 1 232 ARG 232 434 434 ARG ARG D . n 
D 1 233 LEU 233 435 435 LEU LEU D . n 
D 1 234 MET 234 436 436 MET MET D . n 
D 1 235 ASN 235 437 437 ASN ASN D . n 
D 1 236 PRO 236 438 438 PRO PRO D . n 
D 1 237 LEU 237 439 ?   ?   ?   D . n 
D 1 238 ILE 238 440 ?   ?   ?   D . n 
D 1 239 ASP 239 441 ?   ?   ?   D . n 
D 1 240 GLN 240 442 442 GLN GLN D . n 
D 1 241 TYR 241 443 443 TYR TYR D . n 
D 1 242 LEU 242 444 444 LEU LEU D . n 
D 1 243 TYR 243 445 445 TYR TYR D . n 
D 1 244 TYR 244 446 446 TYR TYR D . n 
D 1 245 LEU 245 447 447 LEU LEU D . n 
D 1 246 SER 246 448 448 SER SER D . n 
D 1 247 LYS 247 449 449 LYS LYS D . n 
D 1 248 THR 248 450 450 THR THR D . n 
D 1 249 ILE 249 451 451 ILE ILE D . n 
D 1 250 ASN 250 452 452 ASN ASN D . n 
D 1 251 GLY 251 453 453 GLY GLY D . n 
D 1 252 SER 252 454 454 SER SER D . n 
D 1 253 GLY 253 455 455 GLY GLY D . n 
D 1 254 GLN 254 456 456 GLN GLN D . n 
D 1 255 ASN 255 457 457 ASN ASN D . n 
D 1 256 GLN 256 458 458 GLN GLN D . n 
D 1 257 GLN 257 459 459 GLN GLN D . n 
D 1 258 THR 258 460 460 THR THR D . n 
D 1 259 LEU 259 461 461 LEU LEU D . n 
D 1 260 LYS 260 462 462 LYS LYS D . n 
D 1 261 PHE 261 463 463 PHE PHE D . n 
D 1 262 SER 262 464 464 SER SER D . n 
D 1 263 VAL 263 465 465 VAL VAL D . n 
D 1 264 ALA 264 466 466 ALA ALA D . n 
D 1 265 GLY 265 467 467 GLY GLY D . n 
D 1 266 PRO 266 468 468 PRO PRO D . n 
D 1 267 SER 267 469 469 SER SER D . n 
D 1 268 ASN 268 470 470 ASN ASN D . n 
D 1 269 MET 269 471 471 MET MET D . n 
D 1 270 ALA 270 472 472 ALA ALA D . n 
D 1 271 VAL 271 473 473 VAL VAL D . n 
D 1 272 GLN 272 474 474 GLN GLN D . n 
D 1 273 GLY 273 475 475 GLY GLY D . n 
D 1 274 ARG 274 476 476 ARG ARG D . n 
D 1 275 ASN 275 477 477 ASN ASN D . n 
D 1 276 TYR 276 478 478 TYR TYR D . n 
D 1 277 ILE 277 479 479 ILE ILE D . n 
D 1 278 PRO 278 480 480 PRO PRO D . n 
D 1 279 GLY 279 481 481 GLY GLY D . n 
D 1 280 PRO 280 482 482 PRO PRO D . n 
D 1 281 SER 281 483 483 SER SER D . n 
D 1 282 TYR 282 484 484 TYR TYR D . n 
D 1 283 ARG 283 485 485 ARG ARG D . n 
D 1 284 GLN 284 486 486 GLN GLN D . n 
D 1 285 GLN 285 487 487 GLN GLN D . n 
D 1 286 ARG 286 488 488 ARG ARG D . n 
D 1 287 VAL 287 489 489 VAL VAL D . n 
D 1 288 SER 288 490 490 SER SER D . n 
D 1 289 THR 289 491 491 THR THR D . n 
D 1 290 THR 290 492 492 THR THR D . n 
D 1 291 VAL 291 493 493 VAL VAL D . n 
D 1 292 THR 292 494 494 THR THR D . n 
D 1 293 GLN 293 495 495 GLN GLN D . n 
D 1 294 ASN 294 496 496 ASN ASN D . n 
D 1 295 ASN 295 497 497 ASN ASN D . n 
D 1 296 ASN 296 498 498 ASN ASN D . n 
D 1 297 SER 297 499 499 SER SER D . n 
D 1 298 GLU 298 500 500 GLU GLU D . n 
D 1 299 PHE 299 501 501 PHE PHE D . n 
D 1 300 ALA 300 502 502 ALA ALA D . n 
D 1 301 TRP 301 503 503 TRP TRP D . n 
D 1 302 PRO 302 504 504 PRO PRO D . n 
D 1 303 GLY 303 505 505 GLY GLY D . n 
D 1 304 ALA 304 506 506 ALA ALA D . n 
D 1 305 SER 305 507 507 SER SER D . n 
D 1 306 SER 306 508 508 SER SER D . n 
D 1 307 TRP 307 509 509 TRP TRP D . n 
D 1 308 ALA 308 510 510 ALA ALA D . n 
D 1 309 LEU 309 511 511 LEU LEU D . n 
D 1 310 ASN 310 512 512 ASN ASN D . n 
D 1 311 GLY 311 513 513 GLY GLY D . n 
D 1 312 ARG 312 514 514 ARG ARG D . n 
D 1 313 ASN 313 515 515 ASN ASN D . n 
D 1 314 SER 314 516 516 SER SER D . n 
D 1 315 LEU 315 517 517 LEU LEU D . n 
D 1 316 MET 316 518 518 MET MET D . n 
D 1 317 ASN 317 519 519 ASN ASN D . n 
D 1 318 PRO 318 520 520 PRO PRO D . n 
D 1 319 GLY 319 521 521 GLY GLY D . n 
D 1 320 PRO 320 522 522 PRO PRO D . n 
D 1 321 ALA 321 523 523 ALA ALA D . n 
D 1 322 MET 322 524 524 MET MET D . n 
D 1 323 ALA 323 525 525 ALA ALA D . n 
D 1 324 SER 324 526 526 SER SER D . n 
D 1 325 HIS 325 527 527 HIS HIS D . n 
D 1 326 LYS 326 528 528 LYS LYS D . n 
D 1 327 GLU 327 529 529 GLU GLU D . n 
D 1 328 GLY 328 530 530 GLY GLY D . n 
D 1 329 GLU 329 531 531 GLU GLU D . n 
D 1 330 ASP 330 532 532 ASP ASP D . n 
D 1 331 ARG 331 533 533 ARG ARG D . n 
D 1 332 PHE 332 534 534 PHE PHE D . n 
D 1 333 PHE 333 535 535 PHE PHE D . n 
D 1 334 PRO 334 536 536 PRO PRO D . n 
D 1 335 LEU 335 537 537 LEU LEU D . n 
D 1 336 SER 336 538 538 SER SER D . n 
D 1 337 GLY 337 539 539 GLY GLY D . n 
D 1 338 SER 338 540 540 SER SER D . n 
D 1 339 LEU 339 541 541 LEU LEU D . n 
D 1 340 ILE 340 542 542 ILE ILE D . n 
D 1 341 PHE 341 543 543 PHE PHE D . n 
D 1 342 GLY 342 544 544 GLY GLY D . n 
D 1 343 LYS 343 545 545 LYS LYS D . n 
D 1 344 GLN 344 546 546 GLN GLN D . n 
D 1 345 GLY 345 547 547 GLY GLY D . n 
D 1 346 THR 346 548 548 THR THR D . n 
D 1 347 GLY 347 549 549 GLY GLY D . n 
D 1 348 ARG 348 550 550 ARG ARG D . n 
D 1 349 ASP 349 551 551 ASP ASP D . n 
D 1 350 ASN 350 552 552 ASN ASN D . n 
D 1 351 VAL 351 553 553 VAL VAL D . n 
D 1 352 ASP 352 554 554 ASP ASP D . n 
D 1 353 ALA 353 555 555 ALA ALA D . n 
D 1 354 ASP 354 556 556 ASP ASP D . n 
D 1 355 LYS 355 557 557 LYS LYS D . n 
D 1 356 VAL 356 558 558 VAL VAL D . n 
D 1 357 MET 357 559 559 MET MET D . n 
D 1 358 ILE 358 560 560 ILE ILE D . n 
D 1 359 THR 359 561 561 THR THR D . n 
D 1 360 ASN 360 562 562 ASN ASN D . n 
D 1 361 GLU 361 563 563 GLU GLU D . n 
D 1 362 GLU 362 564 564 GLU GLU D . n 
D 1 363 GLU 363 565 565 GLU GLU D . n 
D 1 364 ILE 364 566 566 ILE ILE D . n 
D 1 365 LYS 365 567 567 LYS LYS D . n 
D 1 366 THR 366 568 568 THR THR D . n 
D 1 367 THR 367 569 569 THR THR D . n 
D 1 368 ASN 368 570 570 ASN ASN D . n 
D 1 369 PRO 369 571 571 PRO PRO D . n 
D 1 370 VAL 370 572 572 VAL VAL D . n 
D 1 371 ALA 371 573 573 ALA ALA D . n 
D 1 372 THR 372 574 574 THR THR D . n 
D 1 373 GLU 373 575 575 GLU GLU D . n 
D 1 374 SER 374 576 576 SER SER D . n 
D 1 375 TYR 375 577 577 TYR TYR D . n 
D 1 376 GLY 376 578 578 GLY GLY D . n 
D 1 377 GLN 377 579 579 GLN GLN D . n 
D 1 378 VAL 378 580 580 VAL VAL D . n 
D 1 379 ALA 379 581 581 ALA ALA D . n 
D 1 380 THR 380 582 582 THR THR D . n 
D 1 381 ASN 381 583 583 ASN ASN D . n 
D 1 382 HIS 382 584 584 HIS HIS D . n 
D 1 383 GLN 383 585 585 GLN GLN D . n 
D 1 384 SER 384 586 586 SER SER D . n 
D 1 385 ALA 385 587 587 ALA ALA D . n 
D 1 386 GLN 386 588 588 GLN GLN D . n 
D 1 387 ALA 387 589 589 ALA ALA D . n 
D 1 388 GLN 388 590 590 GLN GLN D . n 
D 1 389 ALA 389 591 591 ALA ALA D . n 
D 1 390 GLN 390 592 592 GLN GLN D . n 
D 1 391 THR 391 593 593 THR THR D . n 
D 1 392 GLY 392 594 594 GLY GLY D . n 
D 1 393 TRP 393 595 595 TRP TRP D . n 
D 1 394 VAL 394 596 596 VAL VAL D . n 
D 1 395 GLN 395 597 597 GLN GLN D . n 
D 1 396 ASN 396 598 598 ASN ASN D . n 
D 1 397 GLN 397 599 599 GLN GLN D . n 
D 1 398 GLY 398 600 600 GLY GLY D . n 
D 1 399 ILE 399 601 601 ILE ILE D . n 
D 1 400 LEU 400 602 602 LEU LEU D . n 
D 1 401 PRO 401 603 603 PRO PRO D . n 
D 1 402 GLY 402 604 604 GLY GLY D . n 
D 1 403 MET 403 605 605 MET MET D . n 
D 1 404 VAL 404 606 606 VAL VAL D . n 
D 1 405 TRP 405 607 607 TRP TRP D . n 
D 1 406 GLN 406 608 608 GLN GLN D . n 
D 1 407 ASP 407 609 609 ASP ASP D . n 
D 1 408 ARG 408 610 610 ARG ARG D . n 
D 1 409 ASP 409 611 611 ASP ASP D . n 
D 1 410 VAL 410 612 612 VAL VAL D . n 
D 1 411 TYR 411 613 613 TYR TYR D . n 
D 1 412 LEU 412 614 614 LEU LEU D . n 
D 1 413 GLN 413 615 615 GLN GLN D . n 
D 1 414 GLY 414 616 616 GLY GLY D . n 
D 1 415 PRO 415 617 617 PRO PRO D . n 
D 1 416 ILE 416 618 618 ILE ILE D . n 
D 1 417 TRP 417 619 619 TRP TRP D . n 
D 1 418 ALA 418 620 620 ALA ALA D . n 
D 1 419 LYS 419 621 621 LYS LYS D . n 
D 1 420 ILE 420 622 622 ILE ILE D . n 
D 1 421 PRO 421 623 623 PRO PRO D . n 
D 1 422 HIS 422 624 624 HIS HIS D . n 
D 1 423 THR 423 625 625 THR THR D . n 
D 1 424 ASP 424 626 626 ASP ASP D . n 
D 1 425 GLY 425 627 627 GLY GLY D . n 
D 1 426 ASN 426 628 628 ASN ASN D . n 
D 1 427 PHE 427 629 629 PHE PHE D . n 
D 1 428 HIS 428 630 630 HIS HIS D . n 
D 1 429 PRO 429 631 631 PRO PRO D . n 
D 1 430 SER 430 632 632 SER SER D . n 
D 1 431 PRO 431 633 633 PRO PRO D . n 
D 1 432 LEU 432 634 634 LEU LEU D . n 
D 1 433 MET 433 635 635 MET MET D . n 
D 1 434 GLY 434 636 636 GLY GLY D . n 
D 1 435 GLY 435 637 637 GLY GLY D . n 
D 1 436 PHE 436 638 638 PHE PHE D . n 
D 1 437 GLY 437 639 639 GLY GLY D . n 
D 1 438 MET 438 640 640 MET MET D . n 
D 1 439 LYS 439 641 641 LYS LYS D . n 
D 1 440 HIS 440 642 642 HIS HIS D . n 
D 1 441 PRO 441 643 643 PRO PRO D . n 
D 1 442 PRO 442 644 644 PRO PRO D . n 
D 1 443 PRO 443 645 645 PRO PRO D . n 
D 1 444 GLN 444 646 646 GLN GLN D . n 
D 1 445 ILE 445 647 647 ILE ILE D . n 
D 1 446 LEU 446 648 648 LEU LEU D . n 
D 1 447 ILE 447 649 649 ILE ILE D . n 
D 1 448 LYS 448 650 650 LYS LYS D . n 
D 1 449 ASN 449 651 651 ASN ASN D . n 
D 1 450 THR 450 652 652 THR THR D . n 
D 1 451 PRO 451 653 653 PRO PRO D . n 
D 1 452 VAL 452 654 654 VAL VAL D . n 
D 1 453 PRO 453 655 655 PRO PRO D . n 
D 1 454 ALA 454 656 656 ALA ALA D . n 
D 1 455 ASP 455 657 657 ASP ASP D . n 
D 1 456 PRO 456 658 658 PRO PRO D . n 
D 1 457 PRO 457 659 659 PRO PRO D . n 
D 1 458 THR 458 660 660 THR THR D . n 
D 1 459 ALA 459 661 661 ALA ALA D . n 
D 1 460 PHE 460 662 662 PHE PHE D . n 
D 1 461 ASN 461 663 663 ASN ASN D . n 
D 1 462 LYS 462 664 664 LYS LYS D . n 
D 1 463 ASP 463 665 665 ASP ASP D . n 
D 1 464 LYS 464 666 666 LYS LYS D . n 
D 1 465 LEU 465 667 667 LEU LEU D . n 
D 1 466 ASN 466 668 668 ASN ASN D . n 
D 1 467 SER 467 669 669 SER SER D . n 
D 1 468 PHE 468 670 670 PHE PHE D . n 
D 1 469 ILE 469 671 671 ILE ILE D . n 
D 1 470 THR 470 672 672 THR THR D . n 
D 1 471 GLN 471 673 673 GLN GLN D . n 
D 1 472 TYR 472 674 674 TYR TYR D . n 
D 1 473 SER 473 675 675 SER SER D . n 
D 1 474 THR 474 676 676 THR THR D . n 
D 1 475 GLY 475 677 677 GLY GLY D . n 
D 1 476 GLN 476 678 678 GLN GLN D . n 
D 1 477 VAL 477 679 679 VAL VAL D . n 
D 1 478 SER 478 680 680 SER SER D . n 
D 1 479 VAL 479 681 681 VAL VAL D . n 
D 1 480 GLU 480 682 682 GLU GLU D . n 
D 1 481 ILE 481 683 683 ILE ILE D . n 
D 1 482 GLU 482 684 684 GLU GLU D . n 
D 1 483 TRP 483 685 685 TRP TRP D . n 
D 1 484 GLU 484 686 686 GLU GLU D . n 
D 1 485 LEU 485 687 687 LEU LEU D . n 
D 1 486 GLN 486 688 688 GLN GLN D . n 
D 1 487 LYS 487 689 ?   ?   ?   D . n 
D 1 488 GLU 488 690 ?   ?   ?   D . n 
D 1 489 ASN 489 691 ?   ?   ?   D . n 
D 1 490 SER 490 692 ?   ?   ?   D . n 
D 1 491 LYS 491 693 ?   ?   ?   D . n 
D 1 492 ARG 492 694 ?   ?   ?   D . n 
D 1 493 TRP 493 695 ?   ?   ?   D . n 
D 1 494 ASN 494 696 ?   ?   ?   D . n 
D 1 495 PRO 495 697 ?   ?   ?   D . n 
D 1 496 GLU 496 698 ?   ?   ?   D . n 
D 1 497 ILE 497 699 ?   ?   ?   D . n 
D 1 498 GLN 498 700 ?   ?   ?   D . n 
D 1 499 TYR 499 701 ?   ?   ?   D . n 
D 1 500 THR 500 702 ?   ?   ?   D . n 
D 1 501 SER 501 703 ?   ?   ?   D . n 
D 1 502 ASN 502 704 ?   ?   ?   D . n 
D 1 503 TYR 503 705 ?   ?   ?   D . n 
D 1 504 TYR 504 706 ?   ?   ?   D . n 
D 1 505 LYS 505 707 ?   ?   ?   D . n 
D 1 506 SER 506 708 ?   ?   ?   D . n 
D 1 507 ASN 507 709 ?   ?   ?   D . n 
D 1 508 ASN 508 710 ?   ?   ?   D . n 
D 1 509 VAL 509 711 ?   ?   ?   D . n 
D 1 510 GLU 510 712 ?   ?   ?   D . n 
D 1 511 PHE 511 713 ?   ?   ?   D . n 
D 1 512 ALA 512 714 ?   ?   ?   D . n 
D 1 513 VAL 513 715 ?   ?   ?   D . n 
D 1 514 ASN 514 716 ?   ?   ?   D . n 
D 1 515 THR 515 717 ?   ?   ?   D . n 
D 1 516 GLU 516 718 ?   ?   ?   D . n 
D 1 517 GLY 517 719 ?   ?   ?   D . n 
D 1 518 VAL 518 720 ?   ?   ?   D . n 
D 1 519 TYR 519 721 ?   ?   ?   D . n 
D 1 520 SER 520 722 ?   ?   ?   D . n 
D 1 521 GLU 521 723 ?   ?   ?   D . n 
D 1 522 PRO 522 724 ?   ?   ?   D . n 
D 1 523 ARG 523 725 ?   ?   ?   D . n 
D 1 524 PRO 524 726 ?   ?   ?   D . n 
D 1 525 ILE 525 727 ?   ?   ?   D . n 
D 1 526 GLY 526 728 ?   ?   ?   D . n 
D 1 527 THR 527 729 ?   ?   ?   D . n 
D 1 528 ARG 528 730 ?   ?   ?   D . n 
D 1 529 TYR 529 731 ?   ?   ?   D . n 
D 1 530 LEU 530 732 ?   ?   ?   D . n 
D 1 531 THR 531 733 ?   ?   ?   D . n 
D 1 532 ARG 532 734 ?   ?   ?   D . n 
D 1 533 ASN 533 735 ?   ?   ?   D . n 
D 1 534 LEU 534 736 ?   ?   ?   D . n 
E 1 1   MET 1   203 ?   ?   ?   E . n 
E 1 2   ALA 2   204 ?   ?   ?   E . n 
E 1 3   SER 3   205 ?   ?   ?   E . n 
E 1 4   GLY 4   206 ?   ?   ?   E . n 
E 1 5   GLY 5   207 ?   ?   ?   E . n 
E 1 6   GLY 6   208 ?   ?   ?   E . n 
E 1 7   ALA 7   209 ?   ?   ?   E . n 
E 1 8   PRO 8   210 ?   ?   ?   E . n 
E 1 9   VAL 9   211 ?   ?   ?   E . n 
E 1 10  ALA 10  212 ?   ?   ?   E . n 
E 1 11  ASP 11  213 ?   ?   ?   E . n 
E 1 12  ASN 12  214 ?   ?   ?   E . n 
E 1 13  ASN 13  215 ?   ?   ?   E . n 
E 1 14  GLU 14  216 ?   ?   ?   E . n 
E 1 15  GLY 15  217 ?   ?   ?   E . n 
E 1 16  ALA 16  218 ?   ?   ?   E . n 
E 1 17  ASP 17  219 ?   ?   ?   E . n 
E 1 18  GLY 18  220 ?   ?   ?   E . n 
E 1 19  VAL 19  221 ?   ?   ?   E . n 
E 1 20  GLY 20  222 ?   ?   ?   E . n 
E 1 21  SER 21  223 ?   ?   ?   E . n 
E 1 22  SER 22  224 ?   ?   ?   E . n 
E 1 23  SER 23  225 ?   ?   ?   E . n 
E 1 24  GLY 24  226 ?   ?   ?   E . n 
E 1 25  ASN 25  227 ?   ?   ?   E . n 
E 1 26  TRP 26  228 ?   ?   ?   E . n 
E 1 27  HIS 27  229 ?   ?   ?   E . n 
E 1 28  CYS 28  230 ?   ?   ?   E . n 
E 1 29  ASP 29  231 ?   ?   ?   E . n 
E 1 30  SER 30  232 ?   ?   ?   E . n 
E 1 31  GLN 31  233 ?   ?   ?   E . n 
E 1 32  TRP 32  234 ?   ?   ?   E . n 
E 1 33  LEU 33  235 ?   ?   ?   E . n 
E 1 34  GLY 34  236 ?   ?   ?   E . n 
E 1 35  ASP 35  237 ?   ?   ?   E . n 
E 1 36  ARG 36  238 ?   ?   ?   E . n 
E 1 37  VAL 37  239 ?   ?   ?   E . n 
E 1 38  ILE 38  240 ?   ?   ?   E . n 
E 1 39  THR 39  241 ?   ?   ?   E . n 
E 1 40  THR 40  242 ?   ?   ?   E . n 
E 1 41  SER 41  243 ?   ?   ?   E . n 
E 1 42  THR 42  244 ?   ?   ?   E . n 
E 1 43  ARG 43  245 ?   ?   ?   E . n 
E 1 44  THR 44  246 ?   ?   ?   E . n 
E 1 45  TRP 45  247 ?   ?   ?   E . n 
E 1 46  ALA 46  248 ?   ?   ?   E . n 
E 1 47  LEU 47  249 ?   ?   ?   E . n 
E 1 48  PRO 48  250 ?   ?   ?   E . n 
E 1 49  THR 49  251 ?   ?   ?   E . n 
E 1 50  TYR 50  252 ?   ?   ?   E . n 
E 1 51  ASN 51  253 ?   ?   ?   E . n 
E 1 52  ASN 52  254 ?   ?   ?   E . n 
E 1 53  HIS 53  255 ?   ?   ?   E . n 
E 1 54  LEU 54  256 ?   ?   ?   E . n 
E 1 55  TYR 55  257 ?   ?   ?   E . n 
E 1 56  LYS 56  258 ?   ?   ?   E . n 
E 1 57  GLN 57  259 ?   ?   ?   E . n 
E 1 58  ILE 58  260 ?   ?   ?   E . n 
E 1 59  SER 59  261 ?   ?   ?   E . n 
E 1 60  ASN 60  262 ?   ?   ?   E . n 
E 1 61  SER 61  263 ?   ?   ?   E . n 
E 1 62  THR 62  264 ?   ?   ?   E . n 
E 1 63  SER 63  265 ?   ?   ?   E . n 
E 1 64  GLY 64  266 ?   ?   ?   E . n 
E 1 65  GLY 65  267 ?   ?   ?   E . n 
E 1 66  SER 66  268 ?   ?   ?   E . n 
E 1 67  SER 67  269 ?   ?   ?   E . n 
E 1 68  ASN 68  270 ?   ?   ?   E . n 
E 1 69  ASP 69  271 ?   ?   ?   E . n 
E 1 70  ASN 70  272 ?   ?   ?   E . n 
E 1 71  ALA 71  273 ?   ?   ?   E . n 
E 1 72  TYR 72  274 ?   ?   ?   E . n 
E 1 73  PHE 73  275 ?   ?   ?   E . n 
E 1 74  GLY 74  276 ?   ?   ?   E . n 
E 1 75  TYR 75  277 ?   ?   ?   E . n 
E 1 76  SER 76  278 ?   ?   ?   E . n 
E 1 77  THR 77  279 ?   ?   ?   E . n 
E 1 78  PRO 78  280 ?   ?   ?   E . n 
E 1 79  TRP 79  281 ?   ?   ?   E . n 
E 1 80  GLY 80  282 ?   ?   ?   E . n 
E 1 81  TYR 81  283 ?   ?   ?   E . n 
E 1 82  PHE 82  284 ?   ?   ?   E . n 
E 1 83  ASP 83  285 ?   ?   ?   E . n 
E 1 84  PHE 84  286 ?   ?   ?   E . n 
E 1 85  ASN 85  287 ?   ?   ?   E . n 
E 1 86  ARG 86  288 ?   ?   ?   E . n 
E 1 87  PHE 87  289 ?   ?   ?   E . n 
E 1 88  HIS 88  290 ?   ?   ?   E . n 
E 1 89  CYS 89  291 ?   ?   ?   E . n 
E 1 90  HIS 90  292 ?   ?   ?   E . n 
E 1 91  PHE 91  293 ?   ?   ?   E . n 
E 1 92  SER 92  294 ?   ?   ?   E . n 
E 1 93  PRO 93  295 ?   ?   ?   E . n 
E 1 94  ARG 94  296 ?   ?   ?   E . n 
E 1 95  ASP 95  297 ?   ?   ?   E . n 
E 1 96  TRP 96  298 ?   ?   ?   E . n 
E 1 97  GLN 97  299 ?   ?   ?   E . n 
E 1 98  ARG 98  300 ?   ?   ?   E . n 
E 1 99  LEU 99  301 ?   ?   ?   E . n 
E 1 100 ILE 100 302 ?   ?   ?   E . n 
E 1 101 ASN 101 303 ?   ?   ?   E . n 
E 1 102 ASN 102 304 ?   ?   ?   E . n 
E 1 103 ASN 103 305 ?   ?   ?   E . n 
E 1 104 TRP 104 306 ?   ?   ?   E . n 
E 1 105 GLY 105 307 ?   ?   ?   E . n 
E 1 106 PHE 106 308 ?   ?   ?   E . n 
E 1 107 ARG 107 309 ?   ?   ?   E . n 
E 1 108 PRO 108 310 ?   ?   ?   E . n 
E 1 109 LYS 109 311 ?   ?   ?   E . n 
E 1 110 ARG 110 312 ?   ?   ?   E . n 
E 1 111 LEU 111 313 ?   ?   ?   E . n 
E 1 112 ASN 112 314 ?   ?   ?   E . n 
E 1 113 PHE 113 315 ?   ?   ?   E . n 
E 1 114 LYS 114 316 ?   ?   ?   E . n 
E 1 115 LEU 115 317 ?   ?   ?   E . n 
E 1 116 PHE 116 318 ?   ?   ?   E . n 
E 1 117 ASN 117 319 ?   ?   ?   E . n 
E 1 118 ILE 118 320 ?   ?   ?   E . n 
E 1 119 GLN 119 321 ?   ?   ?   E . n 
E 1 120 VAL 120 322 ?   ?   ?   E . n 
E 1 121 LYS 121 323 ?   ?   ?   E . n 
E 1 122 GLU 122 324 ?   ?   ?   E . n 
E 1 123 VAL 123 325 ?   ?   ?   E . n 
E 1 124 THR 124 326 ?   ?   ?   E . n 
E 1 125 ASP 125 327 ?   ?   ?   E . n 
E 1 126 ASN 126 328 ?   ?   ?   E . n 
E 1 127 ASN 127 329 ?   ?   ?   E . n 
E 1 128 GLY 128 330 ?   ?   ?   E . n 
E 1 129 VAL 129 331 ?   ?   ?   E . n 
E 1 130 LYS 130 332 ?   ?   ?   E . n 
E 1 131 THR 131 333 ?   ?   ?   E . n 
E 1 132 ILE 132 334 ?   ?   ?   E . n 
E 1 133 ALA 133 335 ?   ?   ?   E . n 
E 1 134 ASN 134 336 ?   ?   ?   E . n 
E 1 135 ASN 135 337 ?   ?   ?   E . n 
E 1 136 LEU 136 338 ?   ?   ?   E . n 
E 1 137 THR 137 339 ?   ?   ?   E . n 
E 1 138 SER 138 340 ?   ?   ?   E . n 
E 1 139 THR 139 341 ?   ?   ?   E . n 
E 1 140 VAL 140 342 ?   ?   ?   E . n 
E 1 141 GLN 141 343 ?   ?   ?   E . n 
E 1 142 VAL 142 344 ?   ?   ?   E . n 
E 1 143 PHE 143 345 ?   ?   ?   E . n 
E 1 144 THR 144 346 ?   ?   ?   E . n 
E 1 145 ASP 145 347 ?   ?   ?   E . n 
E 1 146 SER 146 348 ?   ?   ?   E . n 
E 1 147 ASP 147 349 ?   ?   ?   E . n 
E 1 148 TYR 148 350 ?   ?   ?   E . n 
E 1 149 GLN 149 351 ?   ?   ?   E . n 
E 1 150 LEU 150 352 ?   ?   ?   E . n 
E 1 151 PRO 151 353 ?   ?   ?   E . n 
E 1 152 TYR 152 354 ?   ?   ?   E . n 
E 1 153 VAL 153 355 ?   ?   ?   E . n 
E 1 154 LEU 154 356 ?   ?   ?   E . n 
E 1 155 GLY 155 357 ?   ?   ?   E . n 
E 1 156 SER 156 358 ?   ?   ?   E . n 
E 1 157 ALA 157 359 ?   ?   ?   E . n 
E 1 158 HIS 158 360 ?   ?   ?   E . n 
E 1 159 GLU 159 361 ?   ?   ?   E . n 
E 1 160 GLY 160 362 ?   ?   ?   E . n 
E 1 161 CYS 161 363 ?   ?   ?   E . n 
E 1 162 LEU 162 364 ?   ?   ?   E . n 
E 1 163 PRO 163 365 ?   ?   ?   E . n 
E 1 164 PRO 164 366 ?   ?   ?   E . n 
E 1 165 PHE 165 367 ?   ?   ?   E . n 
E 1 166 PRO 166 368 ?   ?   ?   E . n 
E 1 167 ALA 167 369 ?   ?   ?   E . n 
E 1 168 ASP 168 370 ?   ?   ?   E . n 
E 1 169 VAL 169 371 ?   ?   ?   E . n 
E 1 170 PHE 170 372 ?   ?   ?   E . n 
E 1 171 MET 171 373 ?   ?   ?   E . n 
E 1 172 ILE 172 374 ?   ?   ?   E . n 
E 1 173 PRO 173 375 ?   ?   ?   E . n 
E 1 174 GLN 174 376 ?   ?   ?   E . n 
E 1 175 TYR 175 377 ?   ?   ?   E . n 
E 1 176 GLY 176 378 ?   ?   ?   E . n 
E 1 177 TYR 177 379 ?   ?   ?   E . n 
E 1 178 LEU 178 380 ?   ?   ?   E . n 
E 1 179 THR 179 381 ?   ?   ?   E . n 
E 1 180 LEU 180 382 ?   ?   ?   E . n 
E 1 181 ASN 181 383 ?   ?   ?   E . n 
E 1 182 ASP 182 384 ?   ?   ?   E . n 
E 1 183 GLY 183 385 ?   ?   ?   E . n 
E 1 184 SER 184 386 ?   ?   ?   E . n 
E 1 185 GLN 185 387 ?   ?   ?   E . n 
E 1 186 ALA 186 388 ?   ?   ?   E . n 
E 1 187 VAL 187 389 ?   ?   ?   E . n 
E 1 188 GLY 188 390 ?   ?   ?   E . n 
E 1 189 ARG 189 391 ?   ?   ?   E . n 
E 1 190 SER 190 392 ?   ?   ?   E . n 
E 1 191 SER 191 393 ?   ?   ?   E . n 
E 1 192 PHE 192 394 ?   ?   ?   E . n 
E 1 193 TYR 193 395 ?   ?   ?   E . n 
E 1 194 CYS 194 396 ?   ?   ?   E . n 
E 1 195 LEU 195 397 ?   ?   ?   E . n 
E 1 196 GLU 196 398 ?   ?   ?   E . n 
E 1 197 TYR 197 399 ?   ?   ?   E . n 
E 1 198 PHE 198 400 ?   ?   ?   E . n 
E 1 199 PRO 199 401 ?   ?   ?   E . n 
E 1 200 SER 200 402 ?   ?   ?   E . n 
E 1 201 GLN 201 403 ?   ?   ?   E . n 
E 1 202 MET 202 404 ?   ?   ?   E . n 
E 1 203 LEU 203 405 ?   ?   ?   E . n 
E 1 204 ARG 204 406 ?   ?   ?   E . n 
E 1 205 THR 205 407 ?   ?   ?   E . n 
E 1 206 GLY 206 408 ?   ?   ?   E . n 
E 1 207 ASN 207 409 ?   ?   ?   E . n 
E 1 208 ASN 208 410 ?   ?   ?   E . n 
E 1 209 PHE 209 411 ?   ?   ?   E . n 
E 1 210 GLN 210 412 ?   ?   ?   E . n 
E 1 211 PHE 211 413 ?   ?   ?   E . n 
E 1 212 SER 212 414 ?   ?   ?   E . n 
E 1 213 TYR 213 415 ?   ?   ?   E . n 
E 1 214 GLU 214 416 ?   ?   ?   E . n 
E 1 215 PHE 215 417 417 PHE PHE E . n 
E 1 216 GLU 216 418 418 GLU GLU E . n 
E 1 217 ASN 217 419 419 ASN ASN E . n 
E 1 218 VAL 218 420 420 VAL VAL E . n 
E 1 219 PRO 219 421 421 PRO PRO E . n 
E 1 220 PHE 220 422 422 PHE PHE E . n 
E 1 221 HIS 221 423 423 HIS HIS E . n 
E 1 222 SER 222 424 424 SER SER E . n 
E 1 223 SER 223 425 425 SER SER E . n 
E 1 224 TYR 224 426 426 TYR TYR E . n 
E 1 225 ALA 225 427 427 ALA ALA E . n 
E 1 226 HIS 226 428 428 HIS HIS E . n 
E 1 227 SER 227 429 429 SER SER E . n 
E 1 228 GLN 228 430 430 GLN GLN E . n 
E 1 229 SER 229 431 431 SER SER E . n 
E 1 230 LEU 230 432 432 LEU LEU E . n 
E 1 231 ASP 231 433 433 ASP ASP E . n 
E 1 232 ARG 232 434 434 ARG ARG E . n 
E 1 233 LEU 233 435 435 LEU LEU E . n 
E 1 234 MET 234 436 436 MET MET E . n 
E 1 235 ASN 235 437 437 ASN ASN E . n 
E 1 236 PRO 236 438 438 PRO PRO E . n 
E 1 237 LEU 237 439 439 LEU LEU E . n 
E 1 238 ILE 238 440 440 ILE ILE E . n 
E 1 239 ASP 239 441 441 ASP ASP E . n 
E 1 240 GLN 240 442 442 GLN GLN E . n 
E 1 241 TYR 241 443 443 TYR TYR E . n 
E 1 242 LEU 242 444 444 LEU LEU E . n 
E 1 243 TYR 243 445 445 TYR TYR E . n 
E 1 244 TYR 244 446 446 TYR TYR E . n 
E 1 245 LEU 245 447 447 LEU LEU E . n 
E 1 246 SER 246 448 448 SER SER E . n 
E 1 247 LYS 247 449 449 LYS LYS E . n 
E 1 248 THR 248 450 450 THR THR E . n 
E 1 249 ILE 249 451 451 ILE ILE E . n 
E 1 250 ASN 250 452 452 ASN ASN E . n 
E 1 251 GLY 251 453 453 GLY GLY E . n 
E 1 252 SER 252 454 454 SER SER E . n 
E 1 253 GLY 253 455 455 GLY GLY E . n 
E 1 254 GLN 254 456 456 GLN GLN E . n 
E 1 255 ASN 255 457 457 ASN ASN E . n 
E 1 256 GLN 256 458 458 GLN GLN E . n 
E 1 257 GLN 257 459 459 GLN GLN E . n 
E 1 258 THR 258 460 460 THR THR E . n 
E 1 259 LEU 259 461 461 LEU LEU E . n 
E 1 260 LYS 260 462 462 LYS LYS E . n 
E 1 261 PHE 261 463 463 PHE PHE E . n 
E 1 262 SER 262 464 464 SER SER E . n 
E 1 263 VAL 263 465 465 VAL VAL E . n 
E 1 264 ALA 264 466 466 ALA ALA E . n 
E 1 265 GLY 265 467 467 GLY GLY E . n 
E 1 266 PRO 266 468 468 PRO PRO E . n 
E 1 267 SER 267 469 469 SER SER E . n 
E 1 268 ASN 268 470 470 ASN ASN E . n 
E 1 269 MET 269 471 471 MET MET E . n 
E 1 270 ALA 270 472 472 ALA ALA E . n 
E 1 271 VAL 271 473 473 VAL VAL E . n 
E 1 272 GLN 272 474 474 GLN GLN E . n 
E 1 273 GLY 273 475 475 GLY GLY E . n 
E 1 274 ARG 274 476 476 ARG ARG E . n 
E 1 275 ASN 275 477 477 ASN ASN E . n 
E 1 276 TYR 276 478 478 TYR TYR E . n 
E 1 277 ILE 277 479 479 ILE ILE E . n 
E 1 278 PRO 278 480 480 PRO PRO E . n 
E 1 279 GLY 279 481 481 GLY GLY E . n 
E 1 280 PRO 280 482 482 PRO PRO E . n 
E 1 281 SER 281 483 483 SER SER E . n 
E 1 282 TYR 282 484 484 TYR TYR E . n 
E 1 283 ARG 283 485 485 ARG ARG E . n 
E 1 284 GLN 284 486 486 GLN GLN E . n 
E 1 285 GLN 285 487 487 GLN GLN E . n 
E 1 286 ARG 286 488 488 ARG ARG E . n 
E 1 287 VAL 287 489 489 VAL VAL E . n 
E 1 288 SER 288 490 490 SER SER E . n 
E 1 289 THR 289 491 491 THR THR E . n 
E 1 290 THR 290 492 492 THR THR E . n 
E 1 291 VAL 291 493 493 VAL VAL E . n 
E 1 292 THR 292 494 494 THR THR E . n 
E 1 293 GLN 293 495 495 GLN GLN E . n 
E 1 294 ASN 294 496 496 ASN ASN E . n 
E 1 295 ASN 295 497 497 ASN ASN E . n 
E 1 296 ASN 296 498 498 ASN ASN E . n 
E 1 297 SER 297 499 499 SER SER E . n 
E 1 298 GLU 298 500 500 GLU GLU E . n 
E 1 299 PHE 299 501 501 PHE PHE E . n 
E 1 300 ALA 300 502 502 ALA ALA E . n 
E 1 301 TRP 301 503 503 TRP TRP E . n 
E 1 302 PRO 302 504 504 PRO PRO E . n 
E 1 303 GLY 303 505 505 GLY GLY E . n 
E 1 304 ALA 304 506 506 ALA ALA E . n 
E 1 305 SER 305 507 507 SER SER E . n 
E 1 306 SER 306 508 508 SER SER E . n 
E 1 307 TRP 307 509 509 TRP TRP E . n 
E 1 308 ALA 308 510 510 ALA ALA E . n 
E 1 309 LEU 309 511 511 LEU LEU E . n 
E 1 310 ASN 310 512 512 ASN ASN E . n 
E 1 311 GLY 311 513 513 GLY GLY E . n 
E 1 312 ARG 312 514 514 ARG ARG E . n 
E 1 313 ASN 313 515 515 ASN ASN E . n 
E 1 314 SER 314 516 516 SER SER E . n 
E 1 315 LEU 315 517 517 LEU LEU E . n 
E 1 316 MET 316 518 518 MET MET E . n 
E 1 317 ASN 317 519 519 ASN ASN E . n 
E 1 318 PRO 318 520 520 PRO PRO E . n 
E 1 319 GLY 319 521 521 GLY GLY E . n 
E 1 320 PRO 320 522 522 PRO PRO E . n 
E 1 321 ALA 321 523 523 ALA ALA E . n 
E 1 322 MET 322 524 524 MET MET E . n 
E 1 323 ALA 323 525 525 ALA ALA E . n 
E 1 324 SER 324 526 526 SER SER E . n 
E 1 325 HIS 325 527 527 HIS HIS E . n 
E 1 326 LYS 326 528 528 LYS LYS E . n 
E 1 327 GLU 327 529 529 GLU GLU E . n 
E 1 328 GLY 328 530 530 GLY GLY E . n 
E 1 329 GLU 329 531 531 GLU GLU E . n 
E 1 330 ASP 330 532 532 ASP ASP E . n 
E 1 331 ARG 331 533 533 ARG ARG E . n 
E 1 332 PHE 332 534 534 PHE PHE E . n 
E 1 333 PHE 333 535 535 PHE PHE E . n 
E 1 334 PRO 334 536 536 PRO PRO E . n 
E 1 335 LEU 335 537 537 LEU LEU E . n 
E 1 336 SER 336 538 538 SER SER E . n 
E 1 337 GLY 337 539 539 GLY GLY E . n 
E 1 338 SER 338 540 540 SER SER E . n 
E 1 339 LEU 339 541 541 LEU LEU E . n 
E 1 340 ILE 340 542 542 ILE ILE E . n 
E 1 341 PHE 341 543 543 PHE PHE E . n 
E 1 342 GLY 342 544 ?   ?   ?   E . n 
E 1 343 LYS 343 545 ?   ?   ?   E . n 
E 1 344 GLN 344 546 ?   ?   ?   E . n 
E 1 345 GLY 345 547 ?   ?   ?   E . n 
E 1 346 THR 346 548 ?   ?   ?   E . n 
E 1 347 GLY 347 549 ?   ?   ?   E . n 
E 1 348 ARG 348 550 ?   ?   ?   E . n 
E 1 349 ASP 349 551 ?   ?   ?   E . n 
E 1 350 ASN 350 552 ?   ?   ?   E . n 
E 1 351 VAL 351 553 ?   ?   ?   E . n 
E 1 352 ASP 352 554 ?   ?   ?   E . n 
E 1 353 ALA 353 555 ?   ?   ?   E . n 
E 1 354 ASP 354 556 ?   ?   ?   E . n 
E 1 355 LYS 355 557 ?   ?   ?   E . n 
E 1 356 VAL 356 558 558 VAL VAL E . n 
E 1 357 MET 357 559 559 MET MET E . n 
E 1 358 ILE 358 560 560 ILE ILE E . n 
E 1 359 THR 359 561 561 THR THR E . n 
E 1 360 ASN 360 562 562 ASN ASN E . n 
E 1 361 GLU 361 563 563 GLU GLU E . n 
E 1 362 GLU 362 564 564 GLU GLU E . n 
E 1 363 GLU 363 565 565 GLU GLU E . n 
E 1 364 ILE 364 566 566 ILE ILE E . n 
E 1 365 LYS 365 567 567 LYS LYS E . n 
E 1 366 THR 366 568 568 THR THR E . n 
E 1 367 THR 367 569 569 THR THR E . n 
E 1 368 ASN 368 570 570 ASN ASN E . n 
E 1 369 PRO 369 571 571 PRO PRO E . n 
E 1 370 VAL 370 572 572 VAL VAL E . n 
E 1 371 ALA 371 573 573 ALA ALA E . n 
E 1 372 THR 372 574 574 THR THR E . n 
E 1 373 GLU 373 575 575 GLU GLU E . n 
E 1 374 SER 374 576 576 SER SER E . n 
E 1 375 TYR 375 577 577 TYR TYR E . n 
E 1 376 GLY 376 578 578 GLY GLY E . n 
E 1 377 GLN 377 579 579 GLN GLN E . n 
E 1 378 VAL 378 580 580 VAL VAL E . n 
E 1 379 ALA 379 581 581 ALA ALA E . n 
E 1 380 THR 380 582 582 THR THR E . n 
E 1 381 ASN 381 583 583 ASN ASN E . n 
E 1 382 HIS 382 584 584 HIS HIS E . n 
E 1 383 GLN 383 585 585 GLN GLN E . n 
E 1 384 SER 384 586 586 SER SER E . n 
E 1 385 ALA 385 587 587 ALA ALA E . n 
E 1 386 GLN 386 588 588 GLN GLN E . n 
E 1 387 ALA 387 589 589 ALA ALA E . n 
E 1 388 GLN 388 590 590 GLN GLN E . n 
E 1 389 ALA 389 591 591 ALA ALA E . n 
E 1 390 GLN 390 592 592 GLN GLN E . n 
E 1 391 THR 391 593 593 THR THR E . n 
E 1 392 GLY 392 594 594 GLY GLY E . n 
E 1 393 TRP 393 595 595 TRP TRP E . n 
E 1 394 VAL 394 596 596 VAL VAL E . n 
E 1 395 GLN 395 597 597 GLN GLN E . n 
E 1 396 ASN 396 598 598 ASN ASN E . n 
E 1 397 GLN 397 599 599 GLN GLN E . n 
E 1 398 GLY 398 600 600 GLY GLY E . n 
E 1 399 ILE 399 601 601 ILE ILE E . n 
E 1 400 LEU 400 602 602 LEU LEU E . n 
E 1 401 PRO 401 603 603 PRO PRO E . n 
E 1 402 GLY 402 604 604 GLY GLY E . n 
E 1 403 MET 403 605 605 MET MET E . n 
E 1 404 VAL 404 606 606 VAL VAL E . n 
E 1 405 TRP 405 607 607 TRP TRP E . n 
E 1 406 GLN 406 608 608 GLN GLN E . n 
E 1 407 ASP 407 609 609 ASP ASP E . n 
E 1 408 ARG 408 610 610 ARG ARG E . n 
E 1 409 ASP 409 611 611 ASP ASP E . n 
E 1 410 VAL 410 612 612 VAL VAL E . n 
E 1 411 TYR 411 613 613 TYR TYR E . n 
E 1 412 LEU 412 614 614 LEU LEU E . n 
E 1 413 GLN 413 615 615 GLN GLN E . n 
E 1 414 GLY 414 616 616 GLY GLY E . n 
E 1 415 PRO 415 617 617 PRO PRO E . n 
E 1 416 ILE 416 618 618 ILE ILE E . n 
E 1 417 TRP 417 619 619 TRP TRP E . n 
E 1 418 ALA 418 620 620 ALA ALA E . n 
E 1 419 LYS 419 621 621 LYS LYS E . n 
E 1 420 ILE 420 622 622 ILE ILE E . n 
E 1 421 PRO 421 623 623 PRO PRO E . n 
E 1 422 HIS 422 624 624 HIS HIS E . n 
E 1 423 THR 423 625 625 THR THR E . n 
E 1 424 ASP 424 626 626 ASP ASP E . n 
E 1 425 GLY 425 627 627 GLY GLY E . n 
E 1 426 ASN 426 628 628 ASN ASN E . n 
E 1 427 PHE 427 629 629 PHE PHE E . n 
E 1 428 HIS 428 630 630 HIS HIS E . n 
E 1 429 PRO 429 631 631 PRO PRO E . n 
E 1 430 SER 430 632 632 SER SER E . n 
E 1 431 PRO 431 633 633 PRO PRO E . n 
E 1 432 LEU 432 634 634 LEU LEU E . n 
E 1 433 MET 433 635 635 MET MET E . n 
E 1 434 GLY 434 636 636 GLY GLY E . n 
E 1 435 GLY 435 637 637 GLY GLY E . n 
E 1 436 PHE 436 638 638 PHE PHE E . n 
E 1 437 GLY 437 639 639 GLY GLY E . n 
E 1 438 MET 438 640 640 MET MET E . n 
E 1 439 LYS 439 641 641 LYS LYS E . n 
E 1 440 HIS 440 642 642 HIS HIS E . n 
E 1 441 PRO 441 643 643 PRO PRO E . n 
E 1 442 PRO 442 644 644 PRO PRO E . n 
E 1 443 PRO 443 645 ?   ?   ?   E . n 
E 1 444 GLN 444 646 ?   ?   ?   E . n 
E 1 445 ILE 445 647 ?   ?   ?   E . n 
E 1 446 LEU 446 648 ?   ?   ?   E . n 
E 1 447 ILE 447 649 ?   ?   ?   E . n 
E 1 448 LYS 448 650 ?   ?   ?   E . n 
E 1 449 ASN 449 651 ?   ?   ?   E . n 
E 1 450 THR 450 652 ?   ?   ?   E . n 
E 1 451 PRO 451 653 ?   ?   ?   E . n 
E 1 452 VAL 452 654 ?   ?   ?   E . n 
E 1 453 PRO 453 655 ?   ?   ?   E . n 
E 1 454 ALA 454 656 ?   ?   ?   E . n 
E 1 455 ASP 455 657 ?   ?   ?   E . n 
E 1 456 PRO 456 658 ?   ?   ?   E . n 
E 1 457 PRO 457 659 ?   ?   ?   E . n 
E 1 458 THR 458 660 ?   ?   ?   E . n 
E 1 459 ALA 459 661 ?   ?   ?   E . n 
E 1 460 PHE 460 662 ?   ?   ?   E . n 
E 1 461 ASN 461 663 ?   ?   ?   E . n 
E 1 462 LYS 462 664 ?   ?   ?   E . n 
E 1 463 ASP 463 665 ?   ?   ?   E . n 
E 1 464 LYS 464 666 ?   ?   ?   E . n 
E 1 465 LEU 465 667 ?   ?   ?   E . n 
E 1 466 ASN 466 668 ?   ?   ?   E . n 
E 1 467 SER 467 669 ?   ?   ?   E . n 
E 1 468 PHE 468 670 ?   ?   ?   E . n 
E 1 469 ILE 469 671 ?   ?   ?   E . n 
E 1 470 THR 470 672 ?   ?   ?   E . n 
E 1 471 GLN 471 673 ?   ?   ?   E . n 
E 1 472 TYR 472 674 ?   ?   ?   E . n 
E 1 473 SER 473 675 ?   ?   ?   E . n 
E 1 474 THR 474 676 ?   ?   ?   E . n 
E 1 475 GLY 475 677 ?   ?   ?   E . n 
E 1 476 GLN 476 678 ?   ?   ?   E . n 
E 1 477 VAL 477 679 ?   ?   ?   E . n 
E 1 478 SER 478 680 ?   ?   ?   E . n 
E 1 479 VAL 479 681 ?   ?   ?   E . n 
E 1 480 GLU 480 682 ?   ?   ?   E . n 
E 1 481 ILE 481 683 ?   ?   ?   E . n 
E 1 482 GLU 482 684 ?   ?   ?   E . n 
E 1 483 TRP 483 685 ?   ?   ?   E . n 
E 1 484 GLU 484 686 ?   ?   ?   E . n 
E 1 485 LEU 485 687 ?   ?   ?   E . n 
E 1 486 GLN 486 688 ?   ?   ?   E . n 
E 1 487 LYS 487 689 ?   ?   ?   E . n 
E 1 488 GLU 488 690 ?   ?   ?   E . n 
E 1 489 ASN 489 691 ?   ?   ?   E . n 
E 1 490 SER 490 692 ?   ?   ?   E . n 
E 1 491 LYS 491 693 ?   ?   ?   E . n 
E 1 492 ARG 492 694 ?   ?   ?   E . n 
E 1 493 TRP 493 695 ?   ?   ?   E . n 
E 1 494 ASN 494 696 ?   ?   ?   E . n 
E 1 495 PRO 495 697 ?   ?   ?   E . n 
E 1 496 GLU 496 698 ?   ?   ?   E . n 
E 1 497 ILE 497 699 ?   ?   ?   E . n 
E 1 498 GLN 498 700 ?   ?   ?   E . n 
E 1 499 TYR 499 701 ?   ?   ?   E . n 
E 1 500 THR 500 702 ?   ?   ?   E . n 
E 1 501 SER 501 703 ?   ?   ?   E . n 
E 1 502 ASN 502 704 ?   ?   ?   E . n 
E 1 503 TYR 503 705 ?   ?   ?   E . n 
E 1 504 TYR 504 706 ?   ?   ?   E . n 
E 1 505 LYS 505 707 ?   ?   ?   E . n 
E 1 506 SER 506 708 ?   ?   ?   E . n 
E 1 507 ASN 507 709 ?   ?   ?   E . n 
E 1 508 ASN 508 710 ?   ?   ?   E . n 
E 1 509 VAL 509 711 ?   ?   ?   E . n 
E 1 510 GLU 510 712 ?   ?   ?   E . n 
E 1 511 PHE 511 713 ?   ?   ?   E . n 
E 1 512 ALA 512 714 ?   ?   ?   E . n 
E 1 513 VAL 513 715 ?   ?   ?   E . n 
E 1 514 ASN 514 716 ?   ?   ?   E . n 
E 1 515 THR 515 717 ?   ?   ?   E . n 
E 1 516 GLU 516 718 ?   ?   ?   E . n 
E 1 517 GLY 517 719 ?   ?   ?   E . n 
E 1 518 VAL 518 720 ?   ?   ?   E . n 
E 1 519 TYR 519 721 ?   ?   ?   E . n 
E 1 520 SER 520 722 ?   ?   ?   E . n 
E 1 521 GLU 521 723 ?   ?   ?   E . n 
E 1 522 PRO 522 724 ?   ?   ?   E . n 
E 1 523 ARG 523 725 ?   ?   ?   E . n 
E 1 524 PRO 524 726 ?   ?   ?   E . n 
E 1 525 ILE 525 727 ?   ?   ?   E . n 
E 1 526 GLY 526 728 ?   ?   ?   E . n 
E 1 527 THR 527 729 ?   ?   ?   E . n 
E 1 528 ARG 528 730 ?   ?   ?   E . n 
E 1 529 TYR 529 731 ?   ?   ?   E . n 
E 1 530 LEU 530 732 ?   ?   ?   E . n 
E 1 531 THR 531 733 ?   ?   ?   E . n 
E 1 532 ARG 532 734 ?   ?   ?   E . n 
E 1 533 ASN 533 735 ?   ?   ?   E . n 
E 1 534 LEU 534 736 ?   ?   ?   E . n 
F 1 1   MET 1   203 ?   ?   ?   F . n 
F 1 2   ALA 2   204 ?   ?   ?   F . n 
F 1 3   SER 3   205 ?   ?   ?   F . n 
F 1 4   GLY 4   206 ?   ?   ?   F . n 
F 1 5   GLY 5   207 ?   ?   ?   F . n 
F 1 6   GLY 6   208 ?   ?   ?   F . n 
F 1 7   ALA 7   209 ?   ?   ?   F . n 
F 1 8   PRO 8   210 ?   ?   ?   F . n 
F 1 9   VAL 9   211 ?   ?   ?   F . n 
F 1 10  ALA 10  212 ?   ?   ?   F . n 
F 1 11  ASP 11  213 ?   ?   ?   F . n 
F 1 12  ASN 12  214 ?   ?   ?   F . n 
F 1 13  ASN 13  215 ?   ?   ?   F . n 
F 1 14  GLU 14  216 ?   ?   ?   F . n 
F 1 15  GLY 15  217 ?   ?   ?   F . n 
F 1 16  ALA 16  218 ?   ?   ?   F . n 
F 1 17  ASP 17  219 219 ASP ASP F . n 
F 1 18  GLY 18  220 220 GLY GLY F . n 
F 1 19  VAL 19  221 221 VAL VAL F . n 
F 1 20  GLY 20  222 222 GLY GLY F . n 
F 1 21  SER 21  223 223 SER SER F . n 
F 1 22  SER 22  224 224 SER SER F . n 
F 1 23  SER 23  225 225 SER SER F . n 
F 1 24  GLY 24  226 226 GLY GLY F . n 
F 1 25  ASN 25  227 227 ASN ASN F . n 
F 1 26  TRP 26  228 228 TRP TRP F . n 
F 1 27  HIS 27  229 229 HIS HIS F . n 
F 1 28  CYS 28  230 230 CYS CYS F . n 
F 1 29  ASP 29  231 231 ASP ASP F . n 
F 1 30  SER 30  232 232 SER SER F . n 
F 1 31  GLN 31  233 233 GLN GLN F . n 
F 1 32  TRP 32  234 234 TRP TRP F . n 
F 1 33  LEU 33  235 235 LEU LEU F . n 
F 1 34  GLY 34  236 236 GLY GLY F . n 
F 1 35  ASP 35  237 237 ASP ASP F . n 
F 1 36  ARG 36  238 238 ARG ARG F . n 
F 1 37  VAL 37  239 239 VAL VAL F . n 
F 1 38  ILE 38  240 240 ILE ILE F . n 
F 1 39  THR 39  241 241 THR THR F . n 
F 1 40  THR 40  242 242 THR THR F . n 
F 1 41  SER 41  243 243 SER SER F . n 
F 1 42  THR 42  244 244 THR THR F . n 
F 1 43  ARG 43  245 245 ARG ARG F . n 
F 1 44  THR 44  246 246 THR THR F . n 
F 1 45  TRP 45  247 247 TRP TRP F . n 
F 1 46  ALA 46  248 248 ALA ALA F . n 
F 1 47  LEU 47  249 249 LEU LEU F . n 
F 1 48  PRO 48  250 250 PRO PRO F . n 
F 1 49  THR 49  251 251 THR THR F . n 
F 1 50  TYR 50  252 252 TYR TYR F . n 
F 1 51  ASN 51  253 253 ASN ASN F . n 
F 1 52  ASN 52  254 254 ASN ASN F . n 
F 1 53  HIS 53  255 255 HIS HIS F . n 
F 1 54  LEU 54  256 256 LEU LEU F . n 
F 1 55  TYR 55  257 257 TYR TYR F . n 
F 1 56  LYS 56  258 258 LYS LYS F . n 
F 1 57  GLN 57  259 259 GLN GLN F . n 
F 1 58  ILE 58  260 260 ILE ILE F . n 
F 1 59  SER 59  261 261 SER SER F . n 
F 1 60  ASN 60  262 262 ASN ASN F . n 
F 1 61  SER 61  263 263 SER SER F . n 
F 1 62  THR 62  264 264 THR THR F . n 
F 1 63  SER 63  265 265 SER SER F . n 
F 1 64  GLY 64  266 266 GLY GLY F . n 
F 1 65  GLY 65  267 267 GLY GLY F . n 
F 1 66  SER 66  268 268 SER SER F . n 
F 1 67  SER 67  269 269 SER SER F . n 
F 1 68  ASN 68  270 270 ASN ASN F . n 
F 1 69  ASP 69  271 271 ASP ASP F . n 
F 1 70  ASN 70  272 272 ASN ASN F . n 
F 1 71  ALA 71  273 273 ALA ALA F . n 
F 1 72  TYR 72  274 274 TYR TYR F . n 
F 1 73  PHE 73  275 275 PHE PHE F . n 
F 1 74  GLY 74  276 276 GLY GLY F . n 
F 1 75  TYR 75  277 277 TYR TYR F . n 
F 1 76  SER 76  278 278 SER SER F . n 
F 1 77  THR 77  279 279 THR THR F . n 
F 1 78  PRO 78  280 280 PRO PRO F . n 
F 1 79  TRP 79  281 281 TRP TRP F . n 
F 1 80  GLY 80  282 282 GLY GLY F . n 
F 1 81  TYR 81  283 283 TYR TYR F . n 
F 1 82  PHE 82  284 284 PHE PHE F . n 
F 1 83  ASP 83  285 285 ASP ASP F . n 
F 1 84  PHE 84  286 286 PHE PHE F . n 
F 1 85  ASN 85  287 287 ASN ASN F . n 
F 1 86  ARG 86  288 288 ARG ARG F . n 
F 1 87  PHE 87  289 289 PHE PHE F . n 
F 1 88  HIS 88  290 290 HIS HIS F . n 
F 1 89  CYS 89  291 291 CYS CYS F . n 
F 1 90  HIS 90  292 292 HIS HIS F . n 
F 1 91  PHE 91  293 293 PHE PHE F . n 
F 1 92  SER 92  294 294 SER SER F . n 
F 1 93  PRO 93  295 295 PRO PRO F . n 
F 1 94  ARG 94  296 296 ARG ARG F . n 
F 1 95  ASP 95  297 297 ASP ASP F . n 
F 1 96  TRP 96  298 298 TRP TRP F . n 
F 1 97  GLN 97  299 299 GLN GLN F . n 
F 1 98  ARG 98  300 300 ARG ARG F . n 
F 1 99  LEU 99  301 301 LEU LEU F . n 
F 1 100 ILE 100 302 302 ILE ILE F . n 
F 1 101 ASN 101 303 303 ASN ASN F . n 
F 1 102 ASN 102 304 304 ASN ASN F . n 
F 1 103 ASN 103 305 305 ASN ASN F . n 
F 1 104 TRP 104 306 306 TRP TRP F . n 
F 1 105 GLY 105 307 307 GLY GLY F . n 
F 1 106 PHE 106 308 308 PHE PHE F . n 
F 1 107 ARG 107 309 309 ARG ARG F . n 
F 1 108 PRO 108 310 310 PRO PRO F . n 
F 1 109 LYS 109 311 311 LYS LYS F . n 
F 1 110 ARG 110 312 312 ARG ARG F . n 
F 1 111 LEU 111 313 313 LEU LEU F . n 
F 1 112 ASN 112 314 314 ASN ASN F . n 
F 1 113 PHE 113 315 315 PHE PHE F . n 
F 1 114 LYS 114 316 316 LYS LYS F . n 
F 1 115 LEU 115 317 317 LEU LEU F . n 
F 1 116 PHE 116 318 318 PHE PHE F . n 
F 1 117 ASN 117 319 319 ASN ASN F . n 
F 1 118 ILE 118 320 320 ILE ILE F . n 
F 1 119 GLN 119 321 321 GLN GLN F . n 
F 1 120 VAL 120 322 322 VAL VAL F . n 
F 1 121 LYS 121 323 323 LYS LYS F . n 
F 1 122 GLU 122 324 324 GLU GLU F . n 
F 1 123 VAL 123 325 325 VAL VAL F . n 
F 1 124 THR 124 326 326 THR THR F . n 
F 1 125 ASP 125 327 327 ASP ASP F . n 
F 1 126 ASN 126 328 328 ASN ASN F . n 
F 1 127 ASN 127 329 329 ASN ASN F . n 
F 1 128 GLY 128 330 330 GLY GLY F . n 
F 1 129 VAL 129 331 331 VAL VAL F . n 
F 1 130 LYS 130 332 332 LYS LYS F . n 
F 1 131 THR 131 333 333 THR THR F . n 
F 1 132 ILE 132 334 334 ILE ILE F . n 
F 1 133 ALA 133 335 335 ALA ALA F . n 
F 1 134 ASN 134 336 336 ASN ASN F . n 
F 1 135 ASN 135 337 337 ASN ASN F . n 
F 1 136 LEU 136 338 338 LEU LEU F . n 
F 1 137 THR 137 339 339 THR THR F . n 
F 1 138 SER 138 340 340 SER SER F . n 
F 1 139 THR 139 341 341 THR THR F . n 
F 1 140 VAL 140 342 342 VAL VAL F . n 
F 1 141 GLN 141 343 343 GLN GLN F . n 
F 1 142 VAL 142 344 344 VAL VAL F . n 
F 1 143 PHE 143 345 345 PHE PHE F . n 
F 1 144 THR 144 346 346 THR THR F . n 
F 1 145 ASP 145 347 347 ASP ASP F . n 
F 1 146 SER 146 348 348 SER SER F . n 
F 1 147 ASP 147 349 349 ASP ASP F . n 
F 1 148 TYR 148 350 350 TYR TYR F . n 
F 1 149 GLN 149 351 351 GLN GLN F . n 
F 1 150 LEU 150 352 352 LEU LEU F . n 
F 1 151 PRO 151 353 353 PRO PRO F . n 
F 1 152 TYR 152 354 354 TYR TYR F . n 
F 1 153 VAL 153 355 355 VAL VAL F . n 
F 1 154 LEU 154 356 356 LEU LEU F . n 
F 1 155 GLY 155 357 357 GLY GLY F . n 
F 1 156 SER 156 358 358 SER SER F . n 
F 1 157 ALA 157 359 359 ALA ALA F . n 
F 1 158 HIS 158 360 360 HIS HIS F . n 
F 1 159 GLU 159 361 361 GLU GLU F . n 
F 1 160 GLY 160 362 362 GLY GLY F . n 
F 1 161 CYS 161 363 363 CYS CYS F . n 
F 1 162 LEU 162 364 364 LEU LEU F . n 
F 1 163 PRO 163 365 365 PRO PRO F . n 
F 1 164 PRO 164 366 366 PRO PRO F . n 
F 1 165 PHE 165 367 367 PHE PHE F . n 
F 1 166 PRO 166 368 368 PRO PRO F . n 
F 1 167 ALA 167 369 369 ALA ALA F . n 
F 1 168 ASP 168 370 370 ASP ASP F . n 
F 1 169 VAL 169 371 371 VAL VAL F . n 
F 1 170 PHE 170 372 372 PHE PHE F . n 
F 1 171 MET 171 373 373 MET MET F . n 
F 1 172 ILE 172 374 374 ILE ILE F . n 
F 1 173 PRO 173 375 375 PRO PRO F . n 
F 1 174 GLN 174 376 376 GLN GLN F . n 
F 1 175 TYR 175 377 377 TYR TYR F . n 
F 1 176 GLY 176 378 378 GLY GLY F . n 
F 1 177 TYR 177 379 379 TYR TYR F . n 
F 1 178 LEU 178 380 380 LEU LEU F . n 
F 1 179 THR 179 381 381 THR THR F . n 
F 1 180 LEU 180 382 382 LEU LEU F . n 
F 1 181 ASN 181 383 383 ASN ASN F . n 
F 1 182 ASP 182 384 384 ASP ASP F . n 
F 1 183 GLY 183 385 385 GLY GLY F . n 
F 1 184 SER 184 386 386 SER SER F . n 
F 1 185 GLN 185 387 387 GLN GLN F . n 
F 1 186 ALA 186 388 388 ALA ALA F . n 
F 1 187 VAL 187 389 389 VAL VAL F . n 
F 1 188 GLY 188 390 390 GLY GLY F . n 
F 1 189 ARG 189 391 391 ARG ARG F . n 
F 1 190 SER 190 392 392 SER SER F . n 
F 1 191 SER 191 393 393 SER SER F . n 
F 1 192 PHE 192 394 394 PHE PHE F . n 
F 1 193 TYR 193 395 395 TYR TYR F . n 
F 1 194 CYS 194 396 396 CYS CYS F . n 
F 1 195 LEU 195 397 397 LEU LEU F . n 
F 1 196 GLU 196 398 398 GLU GLU F . n 
F 1 197 TYR 197 399 399 TYR TYR F . n 
F 1 198 PHE 198 400 400 PHE PHE F . n 
F 1 199 PRO 199 401 401 PRO PRO F . n 
F 1 200 SER 200 402 402 SER SER F . n 
F 1 201 GLN 201 403 403 GLN GLN F . n 
F 1 202 MET 202 404 404 MET MET F . n 
F 1 203 LEU 203 405 405 LEU LEU F . n 
F 1 204 ARG 204 406 406 ARG ARG F . n 
F 1 205 THR 205 407 407 THR THR F . n 
F 1 206 GLY 206 408 408 GLY GLY F . n 
F 1 207 ASN 207 409 409 ASN ASN F . n 
F 1 208 ASN 208 410 410 ASN ASN F . n 
F 1 209 PHE 209 411 411 PHE PHE F . n 
F 1 210 GLN 210 412 412 GLN GLN F . n 
F 1 211 PHE 211 413 413 PHE PHE F . n 
F 1 212 SER 212 414 414 SER SER F . n 
F 1 213 TYR 213 415 415 TYR TYR F . n 
F 1 214 GLU 214 416 416 GLU GLU F . n 
F 1 215 PHE 215 417 417 PHE PHE F . n 
F 1 216 GLU 216 418 418 GLU GLU F . n 
F 1 217 ASN 217 419 419 ASN ASN F . n 
F 1 218 VAL 218 420 420 VAL VAL F . n 
F 1 219 PRO 219 421 421 PRO PRO F . n 
F 1 220 PHE 220 422 422 PHE PHE F . n 
F 1 221 HIS 221 423 423 HIS HIS F . n 
F 1 222 SER 222 424 424 SER SER F . n 
F 1 223 SER 223 425 425 SER SER F . n 
F 1 224 TYR 224 426 426 TYR TYR F . n 
F 1 225 ALA 225 427 427 ALA ALA F . n 
F 1 226 HIS 226 428 428 HIS HIS F . n 
F 1 227 SER 227 429 429 SER SER F . n 
F 1 228 GLN 228 430 430 GLN GLN F . n 
F 1 229 SER 229 431 431 SER SER F . n 
F 1 230 LEU 230 432 432 LEU LEU F . n 
F 1 231 ASP 231 433 433 ASP ASP F . n 
F 1 232 ARG 232 434 434 ARG ARG F . n 
F 1 233 LEU 233 435 435 LEU LEU F . n 
F 1 234 MET 234 436 436 MET MET F . n 
F 1 235 ASN 235 437 437 ASN ASN F . n 
F 1 236 PRO 236 438 438 PRO PRO F . n 
F 1 237 LEU 237 439 439 LEU LEU F . n 
F 1 238 ILE 238 440 440 ILE ILE F . n 
F 1 239 ASP 239 441 441 ASP ASP F . n 
F 1 240 GLN 240 442 442 GLN GLN F . n 
F 1 241 TYR 241 443 443 TYR TYR F . n 
F 1 242 LEU 242 444 444 LEU LEU F . n 
F 1 243 TYR 243 445 445 TYR TYR F . n 
F 1 244 TYR 244 446 446 TYR TYR F . n 
F 1 245 LEU 245 447 447 LEU LEU F . n 
F 1 246 SER 246 448 448 SER SER F . n 
F 1 247 LYS 247 449 449 LYS LYS F . n 
F 1 248 THR 248 450 450 THR THR F . n 
F 1 249 ILE 249 451 451 ILE ILE F . n 
F 1 250 ASN 250 452 452 ASN ASN F . n 
F 1 251 GLY 251 453 453 GLY GLY F . n 
F 1 252 SER 252 454 454 SER SER F . n 
F 1 253 GLY 253 455 455 GLY GLY F . n 
F 1 254 GLN 254 456 456 GLN GLN F . n 
F 1 255 ASN 255 457 457 ASN ASN F . n 
F 1 256 GLN 256 458 458 GLN GLN F . n 
F 1 257 GLN 257 459 459 GLN GLN F . n 
F 1 258 THR 258 460 460 THR THR F . n 
F 1 259 LEU 259 461 461 LEU LEU F . n 
F 1 260 LYS 260 462 462 LYS LYS F . n 
F 1 261 PHE 261 463 463 PHE PHE F . n 
F 1 262 SER 262 464 464 SER SER F . n 
F 1 263 VAL 263 465 465 VAL VAL F . n 
F 1 264 ALA 264 466 466 ALA ALA F . n 
F 1 265 GLY 265 467 467 GLY GLY F . n 
F 1 266 PRO 266 468 468 PRO PRO F . n 
F 1 267 SER 267 469 469 SER SER F . n 
F 1 268 ASN 268 470 470 ASN ASN F . n 
F 1 269 MET 269 471 471 MET MET F . n 
F 1 270 ALA 270 472 472 ALA ALA F . n 
F 1 271 VAL 271 473 473 VAL VAL F . n 
F 1 272 GLN 272 474 474 GLN GLN F . n 
F 1 273 GLY 273 475 475 GLY GLY F . n 
F 1 274 ARG 274 476 476 ARG ARG F . n 
F 1 275 ASN 275 477 477 ASN ASN F . n 
F 1 276 TYR 276 478 478 TYR TYR F . n 
F 1 277 ILE 277 479 479 ILE ILE F . n 
F 1 278 PRO 278 480 480 PRO PRO F . n 
F 1 279 GLY 279 481 481 GLY GLY F . n 
F 1 280 PRO 280 482 482 PRO PRO F . n 
F 1 281 SER 281 483 483 SER SER F . n 
F 1 282 TYR 282 484 484 TYR TYR F . n 
F 1 283 ARG 283 485 485 ARG ARG F . n 
F 1 284 GLN 284 486 486 GLN GLN F . n 
F 1 285 GLN 285 487 487 GLN GLN F . n 
F 1 286 ARG 286 488 488 ARG ARG F . n 
F 1 287 VAL 287 489 489 VAL VAL F . n 
F 1 288 SER 288 490 490 SER SER F . n 
F 1 289 THR 289 491 491 THR THR F . n 
F 1 290 THR 290 492 492 THR THR F . n 
F 1 291 VAL 291 493 493 VAL VAL F . n 
F 1 292 THR 292 494 494 THR THR F . n 
F 1 293 GLN 293 495 495 GLN GLN F . n 
F 1 294 ASN 294 496 496 ASN ASN F . n 
F 1 295 ASN 295 497 497 ASN ASN F . n 
F 1 296 ASN 296 498 498 ASN ASN F . n 
F 1 297 SER 297 499 499 SER SER F . n 
F 1 298 GLU 298 500 500 GLU GLU F . n 
F 1 299 PHE 299 501 501 PHE PHE F . n 
F 1 300 ALA 300 502 502 ALA ALA F . n 
F 1 301 TRP 301 503 503 TRP TRP F . n 
F 1 302 PRO 302 504 504 PRO PRO F . n 
F 1 303 GLY 303 505 505 GLY GLY F . n 
F 1 304 ALA 304 506 506 ALA ALA F . n 
F 1 305 SER 305 507 507 SER SER F . n 
F 1 306 SER 306 508 508 SER SER F . n 
F 1 307 TRP 307 509 509 TRP TRP F . n 
F 1 308 ALA 308 510 510 ALA ALA F . n 
F 1 309 LEU 309 511 511 LEU LEU F . n 
F 1 310 ASN 310 512 512 ASN ASN F . n 
F 1 311 GLY 311 513 513 GLY GLY F . n 
F 1 312 ARG 312 514 514 ARG ARG F . n 
F 1 313 ASN 313 515 515 ASN ASN F . n 
F 1 314 SER 314 516 516 SER SER F . n 
F 1 315 LEU 315 517 517 LEU LEU F . n 
F 1 316 MET 316 518 518 MET MET F . n 
F 1 317 ASN 317 519 519 ASN ASN F . n 
F 1 318 PRO 318 520 520 PRO PRO F . n 
F 1 319 GLY 319 521 521 GLY GLY F . n 
F 1 320 PRO 320 522 522 PRO PRO F . n 
F 1 321 ALA 321 523 523 ALA ALA F . n 
F 1 322 MET 322 524 524 MET MET F . n 
F 1 323 ALA 323 525 525 ALA ALA F . n 
F 1 324 SER 324 526 526 SER SER F . n 
F 1 325 HIS 325 527 527 HIS HIS F . n 
F 1 326 LYS 326 528 528 LYS LYS F . n 
F 1 327 GLU 327 529 529 GLU GLU F . n 
F 1 328 GLY 328 530 530 GLY GLY F . n 
F 1 329 GLU 329 531 531 GLU GLU F . n 
F 1 330 ASP 330 532 532 ASP ASP F . n 
F 1 331 ARG 331 533 533 ARG ARG F . n 
F 1 332 PHE 332 534 534 PHE PHE F . n 
F 1 333 PHE 333 535 535 PHE PHE F . n 
F 1 334 PRO 334 536 536 PRO PRO F . n 
F 1 335 LEU 335 537 537 LEU LEU F . n 
F 1 336 SER 336 538 538 SER SER F . n 
F 1 337 GLY 337 539 539 GLY GLY F . n 
F 1 338 SER 338 540 540 SER SER F . n 
F 1 339 LEU 339 541 541 LEU LEU F . n 
F 1 340 ILE 340 542 542 ILE ILE F . n 
F 1 341 PHE 341 543 543 PHE PHE F . n 
F 1 342 GLY 342 544 544 GLY GLY F . n 
F 1 343 LYS 343 545 545 LYS LYS F . n 
F 1 344 GLN 344 546 546 GLN GLN F . n 
F 1 345 GLY 345 547 547 GLY GLY F . n 
F 1 346 THR 346 548 548 THR THR F . n 
F 1 347 GLY 347 549 549 GLY GLY F . n 
F 1 348 ARG 348 550 550 ARG ARG F . n 
F 1 349 ASP 349 551 551 ASP ASP F . n 
F 1 350 ASN 350 552 552 ASN ASN F . n 
F 1 351 VAL 351 553 553 VAL VAL F . n 
F 1 352 ASP 352 554 554 ASP ASP F . n 
F 1 353 ALA 353 555 555 ALA ALA F . n 
F 1 354 ASP 354 556 556 ASP ASP F . n 
F 1 355 LYS 355 557 557 LYS LYS F . n 
F 1 356 VAL 356 558 558 VAL VAL F . n 
F 1 357 MET 357 559 559 MET MET F . n 
F 1 358 ILE 358 560 560 ILE ILE F . n 
F 1 359 THR 359 561 561 THR THR F . n 
F 1 360 ASN 360 562 562 ASN ASN F . n 
F 1 361 GLU 361 563 563 GLU GLU F . n 
F 1 362 GLU 362 564 564 GLU GLU F . n 
F 1 363 GLU 363 565 565 GLU GLU F . n 
F 1 364 ILE 364 566 566 ILE ILE F . n 
F 1 365 LYS 365 567 567 LYS LYS F . n 
F 1 366 THR 366 568 568 THR THR F . n 
F 1 367 THR 367 569 569 THR THR F . n 
F 1 368 ASN 368 570 570 ASN ASN F . n 
F 1 369 PRO 369 571 571 PRO PRO F . n 
F 1 370 VAL 370 572 572 VAL VAL F . n 
F 1 371 ALA 371 573 573 ALA ALA F . n 
F 1 372 THR 372 574 574 THR THR F . n 
F 1 373 GLU 373 575 575 GLU GLU F . n 
F 1 374 SER 374 576 576 SER SER F . n 
F 1 375 TYR 375 577 577 TYR TYR F . n 
F 1 376 GLY 376 578 578 GLY GLY F . n 
F 1 377 GLN 377 579 579 GLN GLN F . n 
F 1 378 VAL 378 580 580 VAL VAL F . n 
F 1 379 ALA 379 581 581 ALA ALA F . n 
F 1 380 THR 380 582 582 THR THR F . n 
F 1 381 ASN 381 583 583 ASN ASN F . n 
F 1 382 HIS 382 584 584 HIS HIS F . n 
F 1 383 GLN 383 585 585 GLN GLN F . n 
F 1 384 SER 384 586 586 SER SER F . n 
F 1 385 ALA 385 587 587 ALA ALA F . n 
F 1 386 GLN 386 588 588 GLN GLN F . n 
F 1 387 ALA 387 589 589 ALA ALA F . n 
F 1 388 GLN 388 590 590 GLN GLN F . n 
F 1 389 ALA 389 591 591 ALA ALA F . n 
F 1 390 GLN 390 592 592 GLN GLN F . n 
F 1 391 THR 391 593 593 THR THR F . n 
F 1 392 GLY 392 594 594 GLY GLY F . n 
F 1 393 TRP 393 595 595 TRP TRP F . n 
F 1 394 VAL 394 596 596 VAL VAL F . n 
F 1 395 GLN 395 597 597 GLN GLN F . n 
F 1 396 ASN 396 598 598 ASN ASN F . n 
F 1 397 GLN 397 599 599 GLN GLN F . n 
F 1 398 GLY 398 600 600 GLY GLY F . n 
F 1 399 ILE 399 601 601 ILE ILE F . n 
F 1 400 LEU 400 602 602 LEU LEU F . n 
F 1 401 PRO 401 603 603 PRO PRO F . n 
F 1 402 GLY 402 604 604 GLY GLY F . n 
F 1 403 MET 403 605 605 MET MET F . n 
F 1 404 VAL 404 606 606 VAL VAL F . n 
F 1 405 TRP 405 607 607 TRP TRP F . n 
F 1 406 GLN 406 608 608 GLN GLN F . n 
F 1 407 ASP 407 609 609 ASP ASP F . n 
F 1 408 ARG 408 610 610 ARG ARG F . n 
F 1 409 ASP 409 611 611 ASP ASP F . n 
F 1 410 VAL 410 612 612 VAL VAL F . n 
F 1 411 TYR 411 613 613 TYR TYR F . n 
F 1 412 LEU 412 614 614 LEU LEU F . n 
F 1 413 GLN 413 615 615 GLN GLN F . n 
F 1 414 GLY 414 616 616 GLY GLY F . n 
F 1 415 PRO 415 617 617 PRO PRO F . n 
F 1 416 ILE 416 618 618 ILE ILE F . n 
F 1 417 TRP 417 619 619 TRP TRP F . n 
F 1 418 ALA 418 620 620 ALA ALA F . n 
F 1 419 LYS 419 621 621 LYS LYS F . n 
F 1 420 ILE 420 622 622 ILE ILE F . n 
F 1 421 PRO 421 623 623 PRO PRO F . n 
F 1 422 HIS 422 624 624 HIS HIS F . n 
F 1 423 THR 423 625 625 THR THR F . n 
F 1 424 ASP 424 626 626 ASP ASP F . n 
F 1 425 GLY 425 627 627 GLY GLY F . n 
F 1 426 ASN 426 628 628 ASN ASN F . n 
F 1 427 PHE 427 629 629 PHE PHE F . n 
F 1 428 HIS 428 630 630 HIS HIS F . n 
F 1 429 PRO 429 631 631 PRO PRO F . n 
F 1 430 SER 430 632 632 SER SER F . n 
F 1 431 PRO 431 633 633 PRO PRO F . n 
F 1 432 LEU 432 634 634 LEU LEU F . n 
F 1 433 MET 433 635 635 MET MET F . n 
F 1 434 GLY 434 636 636 GLY GLY F . n 
F 1 435 GLY 435 637 637 GLY GLY F . n 
F 1 436 PHE 436 638 638 PHE PHE F . n 
F 1 437 GLY 437 639 639 GLY GLY F . n 
F 1 438 MET 438 640 640 MET MET F . n 
F 1 439 LYS 439 641 641 LYS LYS F . n 
F 1 440 HIS 440 642 642 HIS HIS F . n 
F 1 441 PRO 441 643 643 PRO PRO F . n 
F 1 442 PRO 442 644 644 PRO PRO F . n 
F 1 443 PRO 443 645 ?   ?   ?   F . n 
F 1 444 GLN 444 646 ?   ?   ?   F . n 
F 1 445 ILE 445 647 ?   ?   ?   F . n 
F 1 446 LEU 446 648 ?   ?   ?   F . n 
F 1 447 ILE 447 649 ?   ?   ?   F . n 
F 1 448 LYS 448 650 ?   ?   ?   F . n 
F 1 449 ASN 449 651 ?   ?   ?   F . n 
F 1 450 THR 450 652 ?   ?   ?   F . n 
F 1 451 PRO 451 653 ?   ?   ?   F . n 
F 1 452 VAL 452 654 ?   ?   ?   F . n 
F 1 453 PRO 453 655 ?   ?   ?   F . n 
F 1 454 ALA 454 656 ?   ?   ?   F . n 
F 1 455 ASP 455 657 ?   ?   ?   F . n 
F 1 456 PRO 456 658 ?   ?   ?   F . n 
F 1 457 PRO 457 659 ?   ?   ?   F . n 
F 1 458 THR 458 660 ?   ?   ?   F . n 
F 1 459 ALA 459 661 ?   ?   ?   F . n 
F 1 460 PHE 460 662 ?   ?   ?   F . n 
F 1 461 ASN 461 663 ?   ?   ?   F . n 
F 1 462 LYS 462 664 ?   ?   ?   F . n 
F 1 463 ASP 463 665 ?   ?   ?   F . n 
F 1 464 LYS 464 666 ?   ?   ?   F . n 
F 1 465 LEU 465 667 667 LEU LEU F . n 
F 1 466 ASN 466 668 668 ASN ASN F . n 
F 1 467 SER 467 669 669 SER SER F . n 
F 1 468 PHE 468 670 670 PHE PHE F . n 
F 1 469 ILE 469 671 671 ILE ILE F . n 
F 1 470 THR 470 672 672 THR THR F . n 
F 1 471 GLN 471 673 673 GLN GLN F . n 
F 1 472 TYR 472 674 674 TYR TYR F . n 
F 1 473 SER 473 675 675 SER SER F . n 
F 1 474 THR 474 676 676 THR THR F . n 
F 1 475 GLY 475 677 677 GLY GLY F . n 
F 1 476 GLN 476 678 678 GLN GLN F . n 
F 1 477 VAL 477 679 679 VAL VAL F . n 
F 1 478 SER 478 680 680 SER SER F . n 
F 1 479 VAL 479 681 681 VAL VAL F . n 
F 1 480 GLU 480 682 682 GLU GLU F . n 
F 1 481 ILE 481 683 683 ILE ILE F . n 
F 1 482 GLU 482 684 684 GLU GLU F . n 
F 1 483 TRP 483 685 685 TRP TRP F . n 
F 1 484 GLU 484 686 686 GLU GLU F . n 
F 1 485 LEU 485 687 687 LEU LEU F . n 
F 1 486 GLN 486 688 688 GLN GLN F . n 
F 1 487 LYS 487 689 689 LYS LYS F . n 
F 1 488 GLU 488 690 690 GLU GLU F . n 
F 1 489 ASN 489 691 691 ASN ASN F . n 
F 1 490 SER 490 692 692 SER SER F . n 
F 1 491 LYS 491 693 693 LYS LYS F . n 
F 1 492 ARG 492 694 694 ARG ARG F . n 
F 1 493 TRP 493 695 695 TRP TRP F . n 
F 1 494 ASN 494 696 696 ASN ASN F . n 
F 1 495 PRO 495 697 697 PRO PRO F . n 
F 1 496 GLU 496 698 698 GLU GLU F . n 
F 1 497 ILE 497 699 699 ILE ILE F . n 
F 1 498 GLN 498 700 700 GLN GLN F . n 
F 1 499 TYR 499 701 701 TYR TYR F . n 
F 1 500 THR 500 702 702 THR THR F . n 
F 1 501 SER 501 703 703 SER SER F . n 
F 1 502 ASN 502 704 704 ASN ASN F . n 
F 1 503 TYR 503 705 705 TYR TYR F . n 
F 1 504 TYR 504 706 706 TYR TYR F . n 
F 1 505 LYS 505 707 707 LYS LYS F . n 
F 1 506 SER 506 708 708 SER SER F . n 
F 1 507 ASN 507 709 709 ASN ASN F . n 
F 1 508 ASN 508 710 710 ASN ASN F . n 
F 1 509 VAL 509 711 711 VAL VAL F . n 
F 1 510 GLU 510 712 712 GLU GLU F . n 
F 1 511 PHE 511 713 713 PHE PHE F . n 
F 1 512 ALA 512 714 714 ALA ALA F . n 
F 1 513 VAL 513 715 715 VAL VAL F . n 
F 1 514 ASN 514 716 716 ASN ASN F . n 
F 1 515 THR 515 717 717 THR THR F . n 
F 1 516 GLU 516 718 718 GLU GLU F . n 
F 1 517 GLY 517 719 719 GLY GLY F . n 
F 1 518 VAL 518 720 720 VAL VAL F . n 
F 1 519 TYR 519 721 721 TYR TYR F . n 
F 1 520 SER 520 722 722 SER SER F . n 
F 1 521 GLU 521 723 723 GLU GLU F . n 
F 1 522 PRO 522 724 724 PRO PRO F . n 
F 1 523 ARG 523 725 725 ARG ARG F . n 
F 1 524 PRO 524 726 726 PRO PRO F . n 
F 1 525 ILE 525 727 727 ILE ILE F . n 
F 1 526 GLY 526 728 728 GLY GLY F . n 
F 1 527 THR 527 729 729 THR THR F . n 
F 1 528 ARG 528 730 730 ARG ARG F . n 
F 1 529 TYR 529 731 731 TYR TYR F . n 
F 1 530 LEU 530 732 732 LEU LEU F . n 
F 1 531 THR 531 733 733 THR THR F . n 
F 1 532 ARG 532 734 734 ARG ARG F . n 
F 1 533 ASN 533 735 735 ASN ASN F . n 
F 1 534 LEU 534 736 736 LEU LEU F . n 
G 2 1   SER 1   19  19  SER SER H . n 
G 2 2   GLU 2   20  20  GLU GLU H . n 
G 2 3   VAL 3   21  21  VAL VAL H . n 
G 2 4   GLN 4   22  22  GLN GLN H . n 
G 2 5   LEU 5   23  23  LEU LEU H . n 
G 2 6   LEU 6   24  24  LEU LEU H . n 
G 2 7   GLU 7   25  25  GLU GLU H . n 
G 2 8   SER 8   26  26  SER SER H . n 
G 2 9   GLY 9   27  27  GLY GLY H . n 
G 2 10  GLY 10  28  28  GLY GLY H . n 
G 2 11  GLY 11  29  29  GLY GLY H . n 
G 2 12  LEU 12  30  30  LEU LEU H . n 
G 2 13  VAL 13  31  31  VAL VAL H . n 
G 2 14  GLN 14  32  32  GLN GLN H . n 
G 2 15  PRO 15  33  33  PRO PRO H . n 
G 2 16  GLY 16  34  34  GLY GLY H . n 
G 2 17  LYS 17  35  35  LYS LYS H . n 
G 2 18  SER 18  36  36  SER SER H . n 
G 2 19  LEU 19  37  37  LEU LEU H . n 
G 2 20  ARG 20  38  38  ARG ARG H . n 
G 2 21  LEU 21  39  39  LEU LEU H . n 
G 2 22  SER 22  40  40  SER SER H . n 
G 2 23  CYS 23  41  41  CYS CYS H . n 
G 2 24  ALA 24  42  42  ALA ALA H . n 
G 2 25  ALA 25  43  43  ALA ALA H . n 
G 2 26  SER 26  44  44  SER SER H . n 
G 2 27  GLY 27  45  45  GLY GLY H . n 
G 2 28  PHE 28  46  46  PHE PHE H . n 
G 2 29  SER 29  47  47  SER SER H . n 
G 2 30  PHE 30  48  48  PHE PHE H . n 
G 2 31  SER 31  49  49  SER SER H . n 
G 2 32  ASN 32  50  50  ASN ASN H . n 
G 2 33  TYR 33  51  51  TYR TYR H . n 
G 2 34  ALA 34  52  52  ALA ALA H . n 
G 2 35  MET 35  53  53  MET MET H . n 
G 2 36  SER 36  54  54  SER SER H . n 
G 2 37  TRP 37  55  55  TRP TRP H . n 
G 2 38  VAL 38  56  56  VAL VAL H . n 
G 2 39  ARG 39  57  57  ARG ARG H . n 
G 2 40  GLN 40  58  58  GLN GLN H . n 
G 2 41  ALA 41  59  59  ALA ALA H . n 
G 2 42  PRO 42  60  60  PRO PRO H . n 
G 2 43  GLY 43  61  61  GLY GLY H . n 
G 2 44  LYS 44  62  62  LYS LYS H . n 
G 2 45  GLY 45  63  63  GLY GLY H . n 
G 2 46  LEU 46  64  64  LEU LEU H . n 
G 2 47  GLU 47  65  65  GLU GLU H . n 
G 2 48  TRP 48  66  66  TRP TRP H . n 
G 2 49  VAL 49  67  67  VAL VAL H . n 
G 2 50  SER 50  68  68  SER SER H . n 
G 2 51  GLY 51  69  69  GLY GLY H . n 
G 2 52  ILE 52  70  70  ILE ILE H . n 
G 2 53  SER 53  71  71  SER SER H . n 
G 2 54  GLY 54  72  72  GLY GLY H . n 
G 2 55  SER 55  73  73  SER SER H . n 
G 2 56  GLY 56  74  74  GLY GLY H . n 
G 2 57  GLY 57  75  75  GLY GLY H . n 
G 2 58  SER 58  76  76  SER SER H . n 
G 2 59  THR 59  77  77  THR THR H . n 
G 2 60  ASN 60  78  78  ASN ASN H . n 
G 2 61  TYR 61  79  79  TYR TYR H . n 
G 2 62  ALA 62  80  80  ALA ALA H . n 
G 2 63  GLU 63  81  81  GLU GLU H . n 
G 2 64  SER 64  82  82  SER SER H . n 
G 2 65  VAL 65  83  83  VAL VAL H . n 
G 2 66  ARG 66  84  84  ARG ARG H . n 
G 2 67  GLY 67  85  85  GLY GLY H . n 
G 2 68  ARG 68  86  86  ARG ARG H . n 
G 2 69  PHE 69  87  87  PHE PHE H . n 
G 2 70  THR 70  88  88  THR THR H . n 
G 2 71  ILE 71  89  89  ILE ILE H . n 
G 2 72  SER 72  90  90  SER SER H . n 
G 2 73  ARG 73  91  91  ARG ARG H . n 
G 2 74  ASP 74  92  92  ASP ASP H . n 
G 2 75  ASN 75  93  93  ASN ASN H . n 
G 2 76  SER 76  94  94  SER SER H . n 
G 2 77  LYS 77  95  95  LYS LYS H . n 
G 2 78  ASN 78  96  96  ASN ASN H . n 
G 2 79  THR 79  97  97  THR THR H . n 
G 2 80  LEU 80  98  98  LEU LEU H . n 
G 2 81  TYR 81  99  99  TYR TYR H . n 
G 2 82  LEU 82  100 100 LEU LEU H . n 
G 2 83  GLU 83  101 101 GLU GLU H . n 
G 2 84  MET 84  102 102 MET MET H . n 
G 2 85  ASN 85  103 103 ASN ASN H . n 
G 2 86  SER 86  104 104 SER SER H . n 
G 2 87  LEU 87  105 105 LEU LEU H . n 
G 2 88  ARG 88  106 106 ARG ARG H . n 
G 2 89  VAL 89  107 107 VAL VAL H . n 
G 2 90  GLU 90  108 108 GLU GLU H . n 
G 2 91  ASP 91  109 109 ASP ASP H . n 
G 2 92  THR 92  110 110 THR THR H . n 
G 2 93  ALA 93  111 111 ALA ALA H . n 
G 2 94  VAL 94  112 112 VAL VAL H . n 
G 2 95  TYR 95  113 113 TYR TYR H . n 
G 2 96  TYR 96  114 114 TYR TYR H . n 
G 2 97  CYS 97  115 115 CYS CYS H . n 
G 2 98  ALA 98  116 116 ALA ALA H . n 
G 2 99  LYS 99  117 117 LYS LYS H . n 
G 2 100 GLY 100 118 118 GLY GLY H . n 
G 2 101 MET 101 119 119 MET MET H . n 
G 2 102 SER 102 120 120 SER SER H . n 
G 2 103 TYR 103 121 121 TYR TYR H . n 
G 2 104 TYR 104 122 122 TYR TYR H . n 
G 2 105 ASP 105 123 123 ASP ASP H . n 
G 2 106 ARG 106 124 124 ARG ARG H . n 
G 2 107 SER 107 125 125 SER SER H . n 
G 2 108 GLY 108 126 126 GLY GLY H . n 
G 2 109 TYR 109 127 127 TYR TYR H . n 
G 2 110 PHE 110 128 128 PHE PHE H . n 
G 2 111 TRP 111 129 129 TRP TRP H . n 
G 2 112 ALA 112 130 130 ALA ALA H . n 
G 2 113 LYS 113 131 131 LYS LYS H . n 
G 2 114 TYR 114 132 132 TYR TYR H . n 
G 2 115 HIS 115 133 133 HIS HIS H . n 
G 2 116 TYR 116 134 134 TYR TYR H . n 
G 2 117 GLY 117 135 135 GLY GLY H . n 
G 2 118 MET 118 136 136 MET MET H . n 
G 2 119 ASP 119 137 137 ASP ASP H . n 
G 2 120 VAL 120 138 138 VAL VAL H . n 
G 2 121 TRP 121 139 139 TRP TRP H . n 
G 2 122 GLY 122 140 140 GLY GLY H . n 
G 2 123 GLN 123 141 141 GLN GLN H . n 
G 2 124 GLY 124 142 142 GLY GLY H . n 
G 2 125 ILE 125 143 143 ILE ILE H . n 
G 2 126 THR 126 144 144 THR THR H . n 
G 2 127 VAL 127 145 145 VAL VAL H . n 
G 2 128 THR 128 146 146 THR THR H . n 
G 2 129 VAL 129 147 147 VAL VAL H . n 
G 2 130 SER 130 148 148 SER SER H . n 
G 2 131 SER 131 149 149 SER SER H . n 
H 3 1   VAL 1   23  23  VAL VAL L . n 
H 3 2   LEU 2   24  24  LEU LEU L . n 
H 3 3   THR 3   25  25  THR THR L . n 
H 3 4   GLN 4   26  26  GLN GLN L . n 
H 3 5   PRO 5   27  27  PRO PRO L . n 
H 3 6   PRO 6   28  28  PRO PRO L . n 
H 3 7   SER 7   29  29  SER SER L . n 
H 3 8   ALA 8   30  30  ALA ALA L . n 
H 3 9   SER 9   31  31  SER SER L . n 
H 3 10  GLY 10  32  32  GLY GLY L . n 
H 3 11  THR 11  33  33  THR THR L . n 
H 3 12  PRO 12  34  34  PRO PRO L . n 
H 3 13  GLY 13  35  35  GLY GLY L . n 
H 3 14  GLN 14  36  36  GLN GLN L . n 
H 3 15  ARG 15  37  37  ARG ARG L . n 
H 3 16  VAL 16  38  38  VAL VAL L . n 
H 3 17  THR 17  39  39  THR THR L . n 
H 3 18  ILE 18  40  40  ILE ILE L . n 
H 3 19  SER 19  41  41  SER SER L . n 
H 3 20  CYS 20  42  42  CYS CYS L . n 
H 3 21  SER 21  43  43  SER SER L . n 
H 3 22  GLY 22  44  44  GLY GLY L . n 
H 3 23  SER 23  45  45  SER SER L . n 
H 3 24  SER 24  46  46  SER SER L . n 
H 3 25  SER 25  47  47  SER SER L . n 
H 3 26  ASN 26  48  48  ASN ASN L . n 
H 3 27  ILE 27  49  49  ILE ILE L . n 
H 3 28  GLY 28  50  50  GLY GLY L . n 
H 3 29  SER 29  51  51  SER SER L . n 
H 3 30  ASN 30  52  52  ASN ASN L . n 
H 3 31  TYR 31  53  53  TYR TYR L . n 
H 3 32  VAL 32  54  54  VAL VAL L . n 
H 3 33  TYR 33  55  55  TYR TYR L . n 
H 3 34  TRP 34  56  56  TRP TRP L . n 
H 3 35  TYR 35  57  57  TYR TYR L . n 
H 3 36  GLN 36  58  58  GLN GLN L . n 
H 3 37  GLN 37  59  59  GLN GLN L . n 
H 3 38  ILE 38  60  60  ILE ILE L . n 
H 3 39  PRO 39  61  61  PRO PRO L . n 
H 3 40  GLY 40  62  62  GLY GLY L . n 
H 3 41  THR 41  63  63  THR THR L . n 
H 3 42  ALA 42  64  64  ALA ALA L . n 
H 3 43  PRO 43  65  65  PRO PRO L . n 
H 3 44  LYS 44  66  66  LYS LYS L . n 
H 3 45  LEU 45  67  67  LEU LEU L . n 
H 3 46  LEU 46  68  68  LEU LEU L . n 
H 3 47  ILE 47  69  69  ILE ILE L . n 
H 3 48  TYR 48  70  70  TYR TYR L . n 
H 3 49  SER 49  71  71  SER SER L . n 
H 3 50  ASN 50  72  72  ASN ASN L . n 
H 3 51  ASN 51  73  73  ASN ASN L . n 
H 3 52  GLN 52  74  74  GLN GLN L . n 
H 3 53  ARG 53  75  75  ARG ARG L . n 
H 3 54  PRO 54  76  76  PRO PRO L . n 
H 3 55  SER 55  77  77  SER SER L . n 
H 3 56  GLY 56  78  78  GLY GLY L . n 
H 3 57  VAL 57  79  79  VAL VAL L . n 
H 3 58  PRO 58  80  80  PRO PRO L . n 
H 3 59  ASP 59  81  81  ASP ASP L . n 
H 3 60  ARG 60  82  82  ARG ARG L . n 
H 3 61  PHE 61  83  83  PHE PHE L . n 
H 3 62  SER 62  84  84  SER SER L . n 
H 3 63  GLY 63  85  85  GLY GLY L . n 
H 3 64  SER 64  86  86  SER SER L . n 
H 3 65  LYS 65  87  87  LYS LYS L . n 
H 3 66  SER 66  88  88  SER SER L . n 
H 3 67  GLY 67  89  89  GLY GLY L . n 
H 3 68  THR 68  90  90  THR THR L . n 
H 3 69  SER 69  91  91  SER SER L . n 
H 3 70  ALA 70  92  92  ALA ALA L . n 
H 3 71  SER 71  93  93  SER SER L . n 
H 3 72  LEU 72  94  94  LEU LEU L . n 
H 3 73  ALA 73  95  95  ALA ALA L . n 
H 3 74  ILE 74  96  96  ILE ILE L . n 
H 3 75  SER 75  97  97  SER SER L . n 
H 3 76  GLY 76  98  98  GLY GLY L . n 
H 3 77  LEU 77  99  99  LEU LEU L . n 
H 3 78  ARG 78  100 100 ARG ARG L . n 
H 3 79  SER 79  101 101 SER SER L . n 
H 3 80  GLU 80  102 102 GLU GLU L . n 
H 3 81  ASP 81  103 103 ASP ASP L . n 
H 3 82  GLU 82  104 104 GLU GLU L . n 
H 3 83  ALA 83  105 105 ALA ALA L . n 
H 3 84  ASP 84  106 106 ASP ASP L . n 
H 3 85  TYR 85  107 107 TYR TYR L . n 
H 3 86  TYR 86  108 108 TYR TYR L . n 
H 3 87  CYS 87  109 109 CYS CYS L . n 
H 3 88  ALA 88  110 110 ALA ALA L . n 
H 3 89  ALA 89  111 111 ALA ALA L . n 
H 3 90  TRP 90  112 112 TRP TRP L . n 
H 3 91  ASP 91  113 113 ASP ASP L . n 
H 3 92  ASP 92  114 114 ASP ASP L . n 
H 3 93  SER 93  115 115 SER SER L . n 
H 3 94  LEU 94  116 116 LEU LEU L . n 
H 3 95  SER 95  117 117 SER SER L . n 
H 3 96  GLY 96  118 118 GLY GLY L . n 
H 3 97  ASN 97  119 119 ASN ASN L . n 
H 3 98  TRP 98  120 120 TRP TRP L . n 
H 3 99  VAL 99  121 121 VAL VAL L . n 
H 3 100 PHE 100 122 122 PHE PHE L . n 
H 3 101 GLY 101 123 123 GLY GLY L . n 
H 3 102 GLY 102 124 124 GLY GLY L . n 
H 3 103 GLY 103 125 125 GLY GLY L . n 
H 3 104 THR 104 126 126 THR THR L . n 
H 3 105 LYS 105 127 127 LYS LYS L . n 
H 3 106 LEU 106 128 128 LEU LEU L . n 
H 3 107 THR 107 129 129 THR THR L . n 
H 3 108 VAL 108 130 130 VAL VAL L . n 
H 3 109 LEU 109 131 131 LEU LEU L . n 
H 3 110 GLY 110 132 132 GLY GLY L . n 
# 
_pdbx_nonpoly_scheme.asym_id         I 
_pdbx_nonpoly_scheme.entity_id       4 
_pdbx_nonpoly_scheme.mon_id          HOH 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     201 
_pdbx_nonpoly_scheme.auth_seq_num    201 
_pdbx_nonpoly_scheme.pdb_mon_id      HOH 
_pdbx_nonpoly_scheme.auth_mon_id     HOH 
_pdbx_nonpoly_scheme.pdb_strand_id   H 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9B7K 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9B7K 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9B7K 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9B7K 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            . 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.004 ? 21175 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.667 ? 28832 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 8.557 ? 16782 ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.048 ? 2951  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.004 ? 3837  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9B7K 
_struct.title                        'Fab2-1 in complex with the capsid of Adeno-associated virus type 9' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9B7K 
_struct_keywords.text            
'Adeno-associated virus, AAV, capsid, Fab-complex, antibody, NAb, VIRUS, VIRAL PROTEIN-IMMUNE SYSTEM complex' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN/IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 1 ? 
F N N 1 ? 
G N N 2 ? 
H N N 3 ? 
I N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP Q6JC22_9VIRU Q6JC22 ? 1 
;MASGGGAPVADNNEGADGVGSSSGNWHCDSQWLGDRVITTSTRTWALPTYNNHLYKQISNSTSGGSSNDNAYFGYSTPWG
YFDFNRFHCHFSPRDWQRLINNNWGFRPKRLNFKLFNIQVKEVTDNNGVKTIANNLTSTVQVFTDSDYQLPYVLGSAHEG
CLPPFPADVFMIPQYGYLTLNDGSQAVGRSSFYCLEYFPSQMLRTGNNFQFSYEFENVPFHSSYAHSQSLDRLMNPLIDQ
YLYYLSKTINGSGQNQQTLKFSVAGPSNMAVQGRNYIPGPSYRQQRVSTTVTQNNNSEFAWPGASSWALNGRNSLMNPGP
AMASHKEGEDRFFPLSGSLIFGKQGTGRDNVDADKVMITNEEEIKTTNPVATESYGQVATNHQSAQAQAQTGWVQNQGIL
PGMVWQDRDVYLQGPIWAKIPHTDGNFHPSPLMGGFGMKHPPPQILIKNTPVPADPPTAFNKDKLNSFITQYSTGQVSVE
IEWELQKENSKRWNPEIQYTSNYYKSNNVEFAVNTEGVYSEPRPIGTRYLTRNL
;
203 
2 PDB 9B7K         9B7K   ? 2 ? 1   
3 PDB 9B7K         9B7K   ? 3 ? 1   
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9B7K A 1 ? 534 ? Q6JC22 203 ? 736 ? 203 736 
2 1 9B7K B 1 ? 534 ? Q6JC22 203 ? 736 ? 203 736 
3 1 9B7K C 1 ? 534 ? Q6JC22 203 ? 736 ? 203 736 
4 1 9B7K D 1 ? 534 ? Q6JC22 203 ? 736 ? 203 736 
5 1 9B7K E 1 ? 534 ? Q6JC22 203 ? 736 ? 203 736 
6 1 9B7K F 1 ? 534 ? Q6JC22 203 ? 736 ? 203 736 
7 2 9B7K H 1 ? 131 ? 9B7K   19  ? 149 ? 19  149 
8 3 9B7K L 1 ? 110 ? 9B7K   23  ? 132 ? 23  132 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   octameric 
_pdbx_struct_assembly.oligomeric_count     8 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASN A 60  ? GLY A 64  ? ASN A 262 GLY A 266 1 ? 5  
HELX_P HELX_P2  AA2 ARG A 86  ? HIS A 90  ? ARG A 288 HIS A 292 5 ? 5  
HELX_P HELX_P3  AA3 SER A 92  ? ASN A 103 ? SER A 294 ASN A 305 1 ? 12 
HELX_P HELX_P4  AA4 CYS A 194 ? PHE A 198 ? CYS A 396 PHE A 400 5 ? 5  
HELX_P HELX_P5  AA5 THR A 290 ? ASN A 294 ? THR A 492 ASN A 496 5 ? 5  
HELX_P HELX_P6  AA6 ASP A 352 ? ASP A 354 ? ASP A 554 ASP A 556 5 ? 3  
HELX_P HELX_P7  AA7 GLU A 361 ? THR A 367 ? GLU A 563 THR A 569 5 ? 7  
HELX_P HELX_P8  AA8 THR B 290 ? ASN B 294 ? THR B 492 ASN B 496 5 ? 5  
HELX_P HELX_P9  AA9 GLU B 362 ? THR B 367 ? GLU B 564 THR B 569 5 ? 6  
HELX_P HELX_P10 AB1 TYR C 50  ? LEU C 54  ? TYR C 252 LEU C 256 5 ? 5  
HELX_P HELX_P11 AB2 ASN C 60  ? GLY C 64  ? ASN C 262 GLY C 266 1 ? 5  
HELX_P HELX_P12 AB3 ARG C 86  ? HIS C 90  ? ARG C 288 HIS C 292 5 ? 5  
HELX_P HELX_P13 AB4 SER C 92  ? ASN C 102 ? SER C 294 ASN C 304 1 ? 11 
HELX_P HELX_P14 AB5 CYS C 194 ? PHE C 198 ? CYS C 396 PHE C 400 5 ? 5  
HELX_P HELX_P15 AB6 THR C 290 ? ASN C 294 ? THR C 492 ASN C 496 5 ? 5  
HELX_P HELX_P16 AB7 GLU C 362 ? THR C 367 ? GLU C 564 THR C 569 5 ? 6  
HELX_P HELX_P17 AB8 ARG D 86  ? PHE D 91  ? ARG D 288 PHE D 293 1 ? 6  
HELX_P HELX_P18 AB9 SER D 92  ? ASN D 103 ? SER D 294 ASN D 305 1 ? 12 
HELX_P HELX_P19 AC1 CYS D 194 ? PHE D 198 ? CYS D 396 PHE D 400 5 ? 5  
HELX_P HELX_P20 AC2 SER D 229 ? LEU D 233 ? SER D 431 LEU D 435 5 ? 5  
HELX_P HELX_P21 AC3 THR D 290 ? ASN D 294 ? THR D 492 ASN D 496 5 ? 5  
HELX_P HELX_P22 AC4 ASP D 352 ? ASP D 354 ? ASP D 554 ASP D 556 5 ? 3  
HELX_P HELX_P23 AC5 GLU D 362 ? THR D 367 ? GLU D 564 THR D 569 5 ? 6  
HELX_P HELX_P24 AC6 THR E 290 ? ASN E 294 ? THR E 492 ASN E 496 5 ? 5  
HELX_P HELX_P25 AC7 GLU E 362 ? THR E 367 ? GLU E 564 THR E 569 5 ? 6  
HELX_P HELX_P26 AC8 TYR F 50  ? LEU F 54  ? TYR F 252 LEU F 256 5 ? 5  
HELX_P HELX_P27 AC9 ARG F 86  ? PHE F 91  ? ARG F 288 PHE F 293 1 ? 6  
HELX_P HELX_P28 AD1 SER F 92  ? ASN F 102 ? SER F 294 ASN F 304 1 ? 11 
HELX_P HELX_P29 AD2 CYS F 194 ? PHE F 198 ? CYS F 396 PHE F 400 5 ? 5  
HELX_P HELX_P30 AD3 SER F 229 ? LEU F 233 ? SER F 431 LEU F 435 5 ? 5  
HELX_P HELX_P31 AD4 THR F 290 ? ASN F 294 ? THR F 492 ASN F 496 5 ? 5  
HELX_P HELX_P32 AD5 GLU F 361 ? THR F 367 ? GLU F 563 THR F 569 5 ? 7  
HELX_P HELX_P33 AD6 SER G 29  ? TYR G 33  ? SER H 47  TYR H 51  5 ? 5  
HELX_P HELX_P34 AD7 ARG G 88  ? THR G 92  ? ARG H 106 THR H 110 5 ? 5  
HELX_P HELX_P35 AD8 TRP G 111 ? TYR G 116 ? TRP H 129 TYR H 134 1 ? 6  
HELX_P HELX_P36 AD9 ARG H 78  ? GLU H 82  ? ARG L 100 GLU L 104 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? G CYS 23 SG ? ? ? 1_555 G CYS 97 SG ? ? H CYS 41 H CYS 115 1_555 ? ? ? ? ? ? ? 2.029 ? ? 
disulf2 disulf ? ? H CYS 20 SG ? ? ? 1_555 H CYS 87 SG ? ? L CYS 42 L CYS 109 1_555 ? ? ? ? ? ? ? 2.026 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS G 23 ? CYS G 97 ? CYS H 41 ? 1_555 CYS H 115 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS H 20 ? CYS H 87 ? CYS L 42 ? 1_555 CYS L 109 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 ASN 317 B . ? ASN 519 B PRO 318 B ? PRO 520 B 1 -28.00 
2 ASN 317 C . ? ASN 519 C PRO 318 C ? PRO 520 C 1 -26.48 
3 ASN 317 D . ? ASN 519 D PRO 318 D ? PRO 520 D 1 -22.55 
4 ASN 317 E . ? ASN 519 E PRO 318 E ? PRO 520 E 1 -26.51 
5 ASN 317 F . ? ASN 519 F PRO 318 F ? PRO 520 F 1 -24.62 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 8 ? 
AA2 ? 6 ? 
AA3 ? 2 ? 
AA4 ? 3 ? 
AA5 ? 2 ? 
AA6 ? 2 ? 
AA7 ? 4 ? 
AA8 ? 2 ? 
AA9 ? 4 ? 
AB1 ? 2 ? 
AB2 ? 3 ? 
AB3 ? 2 ? 
AB4 ? 3 ? 
AB5 ? 2 ? 
AB6 ? 2 ? 
AB7 ? 4 ? 
AB8 ? 2 ? 
AB9 ? 8 ? 
AC1 ? 6 ? 
AC2 ? 2 ? 
AC3 ? 2 ? 
AC4 ? 2 ? 
AC5 ? 2 ? 
AC6 ? 2 ? 
AC7 ? 2 ? 
AC8 ? 8 ? 
AC9 ? 6 ? 
AD1 ? 2 ? 
AD2 ? 3 ? 
AD3 ? 2 ? 
AD4 ? 2 ? 
AD5 ? 4 ? 
AD6 ? 2 ? 
AD7 ? 4 ? 
AD8 ? 2 ? 
AD9 ? 3 ? 
AE1 ? 3 ? 
AE2 ? 3 ? 
AE3 ? 2 ? 
AE4 ? 2 ? 
AE5 ? 4 ? 
AE6 ? 2 ? 
AE7 ? 8 ? 
AE8 ? 3 ? 
AE9 ? 2 ? 
AF1 ? 2 ? 
AF2 ? 2 ? 
AF3 ? 2 ? 
AF4 ? 2 ? 
AF5 ? 2 ? 
AF6 ? 2 ? 
AF7 ? 4 ? 
AF8 ? 7 ? 
AF9 ? 6 ? 
AG1 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 5 ? parallel      
AA1 2 8 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 3 6 ? anti-parallel 
AA1 3 7 ? anti-parallel 
AA1 3 8 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 4 ? anti-parallel 
AA2 2 6 ? anti-parallel 
AA2 3 5 ? anti-parallel 
AA2 3 6 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? parallel      
AA4 2 3 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? parallel      
AB2 1 2 ? anti-parallel 
AB2 2 3 ? parallel      
AB3 1 2 ? anti-parallel 
AB4 1 2 ? parallel      
AB4 2 3 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB7 1 2 ? anti-parallel 
AB7 2 3 ? anti-parallel 
AB7 3 4 ? anti-parallel 
AB8 1 2 ? parallel      
AB9 1 2 ? anti-parallel 
AB9 2 5 ? parallel      
AB9 2 8 ? anti-parallel 
AB9 3 4 ? anti-parallel 
AB9 3 6 ? anti-parallel 
AB9 3 7 ? anti-parallel 
AB9 3 8 ? anti-parallel 
AC1 1 2 ? anti-parallel 
AC1 2 4 ? anti-parallel 
AC1 2 6 ? anti-parallel 
AC1 3 5 ? anti-parallel 
AC1 3 6 ? anti-parallel 
AC2 1 2 ? parallel      
AC3 1 2 ? anti-parallel 
AC4 1 2 ? anti-parallel 
AC5 1 2 ? anti-parallel 
AC6 1 2 ? anti-parallel 
AC7 1 2 ? parallel      
AC8 1 2 ? anti-parallel 
AC8 2 5 ? parallel      
AC8 2 8 ? anti-parallel 
AC8 3 4 ? anti-parallel 
AC8 3 6 ? anti-parallel 
AC8 3 7 ? anti-parallel 
AC8 3 8 ? anti-parallel 
AC9 1 2 ? anti-parallel 
AC9 2 4 ? anti-parallel 
AC9 2 6 ? anti-parallel 
AC9 3 5 ? anti-parallel 
AC9 3 6 ? anti-parallel 
AD1 1 2 ? anti-parallel 
AD2 1 2 ? parallel      
AD2 2 3 ? anti-parallel 
AD3 1 2 ? anti-parallel 
AD4 1 2 ? anti-parallel 
AD5 1 2 ? anti-parallel 
AD5 2 3 ? anti-parallel 
AD5 3 4 ? anti-parallel 
AD6 1 2 ? anti-parallel 
AD7 1 2 ? anti-parallel 
AD7 2 3 ? anti-parallel 
AD7 3 4 ? anti-parallel 
AD8 1 2 ? parallel      
AD9 1 2 ? anti-parallel 
AD9 2 3 ? parallel      
AE1 1 2 ? anti-parallel 
AE1 2 3 ? anti-parallel 
AE2 1 2 ? parallel      
AE2 2 3 ? anti-parallel 
AE3 1 2 ? anti-parallel 
AE4 1 2 ? anti-parallel 
AE5 1 2 ? anti-parallel 
AE5 2 3 ? anti-parallel 
AE5 3 4 ? anti-parallel 
AE6 1 2 ? parallel      
AE7 1 2 ? anti-parallel 
AE7 2 5 ? parallel      
AE7 2 8 ? anti-parallel 
AE7 3 4 ? anti-parallel 
AE7 3 6 ? anti-parallel 
AE7 3 7 ? anti-parallel 
AE7 3 8 ? anti-parallel 
AE8 1 2 ? anti-parallel 
AE8 2 3 ? anti-parallel 
AE9 1 2 ? anti-parallel 
AF1 1 2 ? parallel      
AF2 1 2 ? anti-parallel 
AF3 1 2 ? anti-parallel 
AF4 1 2 ? anti-parallel 
AF5 1 2 ? anti-parallel 
AF6 1 2 ? parallel      
AF7 1 2 ? anti-parallel 
AF7 2 3 ? anti-parallel 
AF7 3 4 ? anti-parallel 
AF8 1 7 ? parallel      
AF8 2 3 ? anti-parallel 
AF8 2 5 ? anti-parallel 
AF8 3 4 ? anti-parallel 
AF8 5 6 ? anti-parallel 
AF8 5 7 ? anti-parallel 
AF9 1 6 ? parallel      
AF9 2 3 ? anti-parallel 
AF9 2 4 ? anti-parallel 
AF9 4 5 ? anti-parallel 
AF9 4 6 ? anti-parallel 
AG1 1 2 ? anti-parallel 
AG1 2 3 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ASP A 29  ? LEU A 33  ? ASP A 231 LEU A 235 
AA1 2 ARG A 36  ? LEU A 47  ? ARG A 238 LEU A 249 
AA1 3 GLY A 105 ? ASN A 126 ? GLY A 307 ASN A 328 
AA1 4 VAL A 129 ? ASN A 134 ? VAL A 331 ASN A 336 
AA1 5 VAL A 169 ? MET A 171 ? VAL A 371 MET A 373 
AA1 6 PHE A 209 ? GLU A 214 ? PHE A 411 GLU A 416 
AA1 7 HIS A 221 ? SER A 222 ? HIS A 423 SER A 424 
AA1 8 GLN A 471 ? GLN A 486 ? GLN A 673 GLN A 688 
AA2 1 LYS A 56  ? SER A 59  ? LYS A 258 SER A 261 
AA2 2 PHE A 73  ? PHE A 82  ? PHE A 275 PHE A 284 
AA2 3 VAL A 140 ? ASP A 145 ? VAL A 342 ASP A 347 
AA2 4 GLN A 174 ? LEU A 178 ? GLN A 376 LEU A 380 
AA2 5 GLN A 201 ? LEU A 203 ? GLN A 403 LEU A 405 
AA2 6 GLN A 444 ? ASN A 449 ? GLN A 646 ASN A 651 
AA3 1 TYR A 243 ? LEU A 245 ? TYR A 445 LEU A 447 
AA3 2 PHE A 261 ? VAL A 263 ? PHE A 463 VAL A 465 
AA4 1 ILE A 277 ? PRO A 278 ? ILE A 479 PRO A 480 
AA4 2 MET A 403 ? TRP A 405 ? MET A 605 TRP A 607 
AA4 3 GLY B 425 ? ASN B 426 ? GLY B 627 ASN B 628 
AA5 1 SER A 281 ? TYR A 282 ? SER A 483 TYR A 484 
AA5 2 ASN A 396 ? GLN A 397 ? ASN A 598 GLN A 599 
AA6 1 ARG A 286 ? SER A 288 ? ARG A 488 SER A 490 
AA6 2 PHE A 332 ? PRO A 334 ? PHE A 534 PRO A 536 
AA7 1 ARG A 312 ? LEU A 315 ? ARG A 514 LEU A 517 
AA7 2 SER A 306 ? LEU A 309 ? SER A 508 LEU A 511 
AA7 3 GLY C 376 ? ALA C 379 ? GLY C 578 ALA C 581 
AA7 4 THR C 391 ? VAL C 394 ? THR C 593 VAL C 596 
AA8 1 ILE A 340 ? GLY A 342 ? ILE A 542 GLY A 544 
AA8 2 VAL A 356 ? ILE A 358 ? VAL A 558 ILE A 560 
AA9 1 THR A 391 ? VAL A 394 ? THR A 593 VAL A 596 
AA9 2 GLY A 376 ? ALA A 379 ? GLY A 578 ALA A 581 
AA9 3 SER B 306 ? LEU B 309 ? SER B 508 LEU B 511 
AA9 4 ARG B 312 ? LEU B 315 ? ARG B 514 LEU B 517 
AB1 1 TRP A 417 ? LYS A 419 ? TRP A 619 LYS A 621 
AB1 2 PHE A 436 ? MET A 438 ? PHE A 638 MET A 640 
AB2 1 GLY A 425 ? ASN A 426 ? GLY A 627 ASN A 628 
AB2 2 MET C 403 ? TRP C 405 ? MET C 605 TRP C 607 
AB2 3 ILE C 277 ? PRO C 278 ? ILE C 479 PRO C 480 
AB3 1 TYR B 243 ? LYS B 247 ? TYR B 445 LYS B 449 
AB3 2 LYS B 260 ? VAL B 263 ? LYS B 462 VAL B 465 
AB4 1 ILE B 277 ? PRO B 278 ? ILE B 479 PRO B 480 
AB4 2 MET B 403 ? TRP B 405 ? MET B 605 TRP B 607 
AB4 3 GLY C 425 ? ASN C 426 ? GLY C 627 ASN C 628 
AB5 1 SER B 281 ? TYR B 282 ? SER B 483 TYR B 484 
AB5 2 ASN B 396 ? GLN B 397 ? ASN B 598 GLN B 599 
AB6 1 ARG B 286 ? SER B 288 ? ARG B 488 SER B 490 
AB6 2 PHE B 332 ? PRO B 334 ? PHE B 534 PRO B 536 
AB7 1 THR B 391 ? VAL B 394 ? THR B 593 VAL B 596 
AB7 2 GLY B 376 ? ALA B 379 ? GLY B 578 ALA B 581 
AB7 3 SER C 306 ? LEU C 309 ? SER C 508 LEU C 511 
AB7 4 ARG C 312 ? LEU C 315 ? ARG C 514 LEU C 517 
AB8 1 TRP B 417 ? LYS B 419 ? TRP B 619 LYS B 621 
AB8 2 PHE B 436 ? MET B 438 ? PHE B 638 MET B 640 
AB9 1 ASP C 29  ? LEU C 33  ? ASP C 231 LEU C 235 
AB9 2 ARG C 36  ? PRO C 48  ? ARG C 238 PRO C 250 
AB9 3 ASN C 103 ? ASN C 126 ? ASN C 305 ASN C 328 
AB9 4 VAL C 129 ? ASN C 134 ? VAL C 331 ASN C 336 
AB9 5 VAL C 169 ? MET C 171 ? VAL C 371 MET C 373 
AB9 6 PHE C 209 ? GLU C 214 ? PHE C 411 GLU C 416 
AB9 7 HIS C 221 ? SER C 222 ? HIS C 423 SER C 424 
AB9 8 GLN C 471 ? LYS C 487 ? GLN C 673 LYS C 689 
AC1 1 LYS C 56  ? SER C 59  ? LYS C 258 SER C 261 
AC1 2 PHE C 73  ? TYR C 81  ? PHE C 275 TYR C 283 
AC1 3 VAL C 140 ? THR C 144 ? VAL C 342 THR C 346 
AC1 4 GLN C 174 ? LEU C 178 ? GLN C 376 LEU C 380 
AC1 5 GLN C 201 ? LEU C 203 ? GLN C 403 LEU C 405 
AC1 6 ILE C 445 ? ASN C 449 ? ILE C 647 ASN C 651 
AC2 1 ALA C 225 ? HIS C 226 ? ALA C 427 HIS C 428 
AC2 2 THR C 531 ? ARG C 532 ? THR C 733 ARG C 734 
AC3 1 TYR C 243 ? ILE C 249 ? TYR C 445 ILE C 451 
AC3 2 GLN C 257 ? VAL C 263 ? GLN C 459 VAL C 465 
AC4 1 SER C 281 ? TYR C 282 ? SER C 483 TYR C 484 
AC4 2 ASN C 396 ? GLN C 397 ? ASN C 598 GLN C 599 
AC5 1 ARG C 286 ? SER C 288 ? ARG C 488 SER C 490 
AC5 2 PHE C 332 ? PRO C 334 ? PHE C 534 PRO C 536 
AC6 1 ILE C 340 ? GLY C 342 ? ILE C 542 GLY C 544 
AC6 2 VAL C 356 ? ILE C 358 ? VAL C 558 ILE C 560 
AC7 1 TRP C 417 ? LYS C 419 ? TRP C 619 LYS C 621 
AC7 2 PHE C 436 ? MET C 438 ? PHE C 638 MET C 640 
AC8 1 SER D 30  ? LEU D 33  ? SER D 232 LEU D 235 
AC8 2 ARG D 36  ? LEU D 47  ? ARG D 238 LEU D 249 
AC8 3 GLY D 105 ? THR D 124 ? GLY D 307 THR D 326 
AC8 4 THR D 131 ? ASN D 134 ? THR D 333 ASN D 336 
AC8 5 VAL D 169 ? MET D 171 ? VAL D 371 MET D 373 
AC8 6 PHE D 209 ? GLU D 214 ? PHE D 411 GLU D 416 
AC8 7 HIS D 221 ? SER D 222 ? HIS D 423 SER D 424 
AC8 8 GLN D 471 ? LEU D 485 ? GLN D 673 LEU D 687 
AC9 1 LYS D 56  ? SER D 59  ? LYS D 258 SER D 261 
AC9 2 PHE D 73  ? PHE D 82  ? PHE D 275 PHE D 284 
AC9 3 VAL D 140 ? ASP D 145 ? VAL D 342 ASP D 347 
AC9 4 GLN D 174 ? THR D 179 ? GLN D 376 THR D 381 
AC9 5 GLN D 201 ? LEU D 203 ? GLN D 403 LEU D 405 
AC9 6 GLN D 444 ? ASN D 449 ? GLN D 646 ASN D 651 
AD1 1 TYR D 243 ? ILE D 249 ? TYR D 445 ILE D 451 
AD1 2 GLN D 257 ? VAL D 263 ? GLN D 459 VAL D 465 
AD2 1 ILE D 277 ? PRO D 278 ? ILE D 479 PRO D 480 
AD2 2 MET D 403 ? TRP D 405 ? MET D 605 TRP D 607 
AD2 3 GLY E 425 ? ASN E 426 ? GLY E 627 ASN E 628 
AD3 1 SER D 281 ? TYR D 282 ? SER D 483 TYR D 484 
AD3 2 ASN D 396 ? GLN D 397 ? ASN D 598 GLN D 599 
AD4 1 ARG D 286 ? SER D 288 ? ARG D 488 SER D 490 
AD4 2 PHE D 332 ? PRO D 334 ? PHE D 534 PRO D 536 
AD5 1 ARG D 312 ? LEU D 315 ? ARG D 514 LEU D 517 
AD5 2 SER D 306 ? LEU D 309 ? SER D 508 LEU D 511 
AD5 3 GLY F 376 ? ALA F 379 ? GLY F 578 ALA F 581 
AD5 4 THR F 391 ? VAL F 394 ? THR F 593 VAL F 596 
AD6 1 ILE D 340 ? GLY D 342 ? ILE D 542 GLY D 544 
AD6 2 VAL D 356 ? ILE D 358 ? VAL D 558 ILE D 560 
AD7 1 THR D 391 ? VAL D 394 ? THR D 593 VAL D 596 
AD7 2 GLY D 376 ? ALA D 379 ? GLY D 578 ALA D 581 
AD7 3 SER E 306 ? LEU E 309 ? SER E 508 LEU E 511 
AD7 4 ARG E 312 ? LEU E 315 ? ARG E 514 LEU E 517 
AD8 1 TRP D 417 ? LYS D 419 ? TRP D 619 LYS D 621 
AD8 2 PHE D 436 ? MET D 438 ? PHE D 638 MET D 640 
AD9 1 GLY D 425 ? ASN D 426 ? GLY D 627 ASN D 628 
AD9 2 MET F 403 ? TRP F 405 ? MET F 605 TRP F 607 
AD9 3 ILE F 277 ? PRO F 278 ? ILE F 479 PRO F 480 
AE1 1 TYR E 243 ? ILE E 249 ? TYR E 445 ILE E 451 
AE1 2 GLN E 257 ? VAL E 263 ? GLN E 459 VAL E 465 
AE1 3 VAL F 351 ? ASP F 352 ? VAL F 553 ASP F 554 
AE2 1 ILE E 277 ? PRO E 278 ? ILE E 479 PRO E 480 
AE2 2 MET E 403 ? TRP E 405 ? MET E 605 TRP E 607 
AE2 3 GLY F 425 ? ASN F 426 ? GLY F 627 ASN F 628 
AE3 1 SER E 281 ? TYR E 282 ? SER E 483 TYR E 484 
AE3 2 ASN E 396 ? GLN E 397 ? ASN E 598 GLN E 599 
AE4 1 ARG E 286 ? SER E 288 ? ARG E 488 SER E 490 
AE4 2 PHE E 332 ? PRO E 334 ? PHE E 534 PRO E 536 
AE5 1 THR E 391 ? VAL E 394 ? THR E 593 VAL E 596 
AE5 2 GLY E 376 ? ALA E 379 ? GLY E 578 ALA E 581 
AE5 3 SER F 306 ? LEU F 309 ? SER F 508 LEU F 511 
AE5 4 ARG F 312 ? LEU F 315 ? ARG F 514 LEU F 517 
AE6 1 TRP E 417 ? LYS E 419 ? TRP E 619 LYS E 621 
AE6 2 PHE E 436 ? MET E 438 ? PHE E 638 MET E 640 
AE7 1 SER F 30  ? LEU F 33  ? SER F 232 LEU F 235 
AE7 2 ARG F 36  ? LEU F 47  ? ARG F 238 LEU F 249 
AE7 3 ASN F 103 ? ASN F 126 ? ASN F 305 ASN F 328 
AE7 4 VAL F 129 ? ASN F 134 ? VAL F 331 ASN F 336 
AE7 5 VAL F 169 ? MET F 171 ? VAL F 371 MET F 373 
AE7 6 PHE F 209 ? GLU F 214 ? PHE F 411 GLU F 416 
AE7 7 HIS F 221 ? SER F 222 ? HIS F 423 SER F 424 
AE7 8 GLN F 471 ? LYS F 487 ? GLN F 673 LYS F 689 
AE8 1 LYS F 56  ? SER F 59  ? LYS F 258 SER F 261 
AE8 2 PHE F 73  ? GLY F 80  ? PHE F 275 GLY F 282 
AE8 3 GLN F 174 ? LEU F 178 ? GLN F 376 LEU F 380 
AE9 1 VAL F 140 ? VAL F 142 ? VAL F 342 VAL F 344 
AE9 2 GLN F 201 ? LEU F 203 ? GLN F 403 LEU F 405 
AF1 1 ALA F 225 ? HIS F 226 ? ALA F 427 HIS F 428 
AF1 2 THR F 531 ? ARG F 532 ? THR F 733 ARG F 734 
AF2 1 TYR F 243 ? ILE F 249 ? TYR F 445 ILE F 451 
AF2 2 GLN F 257 ? VAL F 263 ? GLN F 459 VAL F 465 
AF3 1 SER F 281 ? TYR F 282 ? SER F 483 TYR F 484 
AF3 2 ASN F 396 ? GLN F 397 ? ASN F 598 GLN F 599 
AF4 1 ARG F 286 ? SER F 288 ? ARG F 488 SER F 490 
AF4 2 PHE F 332 ? PRO F 334 ? PHE F 534 PRO F 536 
AF5 1 ILE F 340 ? GLY F 342 ? ILE F 542 GLY F 544 
AF5 2 VAL F 356 ? ILE F 358 ? VAL F 558 ILE F 560 
AF6 1 TRP F 417 ? LYS F 419 ? TRP F 619 LYS F 621 
AF6 2 PHE F 436 ? MET F 438 ? PHE F 638 MET F 640 
AF7 1 GLN G 4   ? SER G 8   ? GLN H 22  SER H 26  
AF7 2 LEU G 19  ? SER G 26  ? LEU H 37  SER H 44  
AF7 3 THR G 79  ? MET G 84  ? THR H 97  MET H 102 
AF7 4 PHE G 69  ? ASP G 74  ? PHE H 87  ASP H 92  
AF8 1 LEU G 12  ? VAL G 13  ? LEU H 30  VAL H 31  
AF8 2 MET G 35  ? GLN G 40  ? MET H 53  GLN H 58  
AF8 3 LEU G 46  ? ILE G 52  ? LEU H 64  ILE H 70  
AF8 4 THR G 59  ? TYR G 61  ? THR H 77  TYR H 79  
AF8 5 ALA G 93  ? GLY G 100 ? ALA H 111 GLY H 118 
AF8 6 MET G 118 ? VAL G 120 ? MET H 136 VAL H 138 
AF8 7 ILE G 125 ? VAL G 129 ? ILE H 143 VAL H 147 
AF9 1 SER H 7   ? GLY H 10  ? SER L 29  GLY L 32  
AF9 2 VAL H 32  ? GLN H 37  ? VAL L 54  GLN L 59  
AF9 3 LYS H 44  ? ILE H 47  ? LYS L 66  ILE L 69  
AF9 4 ASP H 84  ? ASP H 91  ? ASP L 106 ASP L 113 
AF9 5 ASN H 97  ? PHE H 100 ? ASN L 119 PHE L 122 
AF9 6 THR H 104 ? VAL H 108 ? THR L 126 VAL L 130 
AG1 1 VAL H 16  ? SER H 21  ? VAL L 38  SER L 43  
AG1 2 SER H 69  ? ILE H 74  ? SER L 91  ILE L 96  
AG1 3 SER H 62  ? SER H 66  ? SER L 84  SER L 88  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ASP A 29  ? N ASP A 231 O THR A 40  ? O THR A 242 
AA1 2 5 N THR A 44  ? N THR A 246 O PHE A 170 ? O PHE A 372 
AA1 2 8 N LEU A 47  ? N LEU A 249 O SER A 473 ? O SER A 675 
AA1 3 4 N THR A 124 ? N THR A 326 O THR A 131 ? O THR A 333 
AA1 3 6 N LEU A 115 ? N LEU A 317 O PHE A 209 ? O PHE A 411 
AA1 3 7 N PHE A 106 ? N PHE A 308 O HIS A 221 ? O HIS A 423 
AA1 3 8 N LYS A 121 ? N LYS A 323 O TYR A 472 ? O TYR A 674 
AA2 1 2 N ILE A 58  ? N ILE A 260 O GLY A 74  ? O GLY A 276 
AA2 2 4 N TRP A 79  ? N TRP A 281 O TYR A 175 ? O TYR A 377 
AA2 2 6 N GLY A 80  ? N GLY A 282 O ILE A 447 ? O ILE A 649 
AA2 3 5 N VAL A 142 ? N VAL A 344 O GLN A 201 ? O GLN A 403 
AA2 3 6 N PHE A 143 ? N PHE A 345 O LEU A 446 ? O LEU A 648 
AA3 1 2 N TYR A 244 ? N TYR A 446 O SER A 262 ? O SER A 464 
AA4 1 2 N ILE A 277 ? N ILE A 479 O VAL A 404 ? O VAL A 606 
AA4 2 3 N TRP A 405 ? N TRP A 607 O GLY B 425 ? O GLY B 627 
AA5 1 2 N SER A 281 ? N SER A 483 O GLN A 397 ? O GLN A 599 
AA6 1 2 N VAL A 287 ? N VAL A 489 O PHE A 333 ? O PHE A 535 
AA7 1 2 O SER A 314 ? O SER A 516 N TRP A 307 ? N TRP A 509 
AA7 2 3 N SER A 306 ? N SER A 508 O GLN C 377 ? O GLN C 579 
AA7 3 4 N GLY C 376 ? N GLY C 578 O VAL C 394 ? O VAL C 596 
AA8 1 2 N PHE A 341 ? N PHE A 543 O MET A 357 ? O MET A 559 
AA9 1 2 O VAL A 394 ? O VAL A 596 N GLY A 376 ? N GLY A 578 
AA9 2 3 N GLN A 377 ? N GLN A 579 O SER B 306 ? O SER B 508 
AA9 3 4 N LEU B 309 ? N LEU B 511 O ARG B 312 ? O ARG B 514 
AB1 1 2 N ALA A 418 ? N ALA A 620 O PHE A 436 ? O PHE A 638 
AB2 1 2 N GLY A 425 ? N GLY A 627 O TRP C 405 ? O TRP C 607 
AB2 2 3 O VAL C 404 ? O VAL C 606 N ILE C 277 ? N ILE C 479 
AB3 1 2 N LYS B 247 ? N LYS B 449 O LYS B 260 ? O LYS B 462 
AB4 1 2 N ILE B 277 ? N ILE B 479 O VAL B 404 ? O VAL B 606 
AB4 2 3 N TRP B 405 ? N TRP B 607 O GLY C 425 ? O GLY C 627 
AB5 1 2 N SER B 281 ? N SER B 483 O GLN B 397 ? O GLN B 599 
AB6 1 2 N VAL B 287 ? N VAL B 489 O PHE B 333 ? O PHE B 535 
AB7 1 2 O VAL B 394 ? O VAL B 596 N GLY B 376 ? N GLY B 578 
AB7 2 3 N GLN B 377 ? N GLN B 579 O SER C 306 ? O SER C 508 
AB7 3 4 N TRP C 307 ? N TRP C 509 O SER C 314 ? O SER C 516 
AB8 1 2 N ALA B 418 ? N ALA B 620 O PHE B 436 ? O PHE B 638 
AB9 1 2 N ASP C 29  ? N ASP C 231 O THR C 40  ? O THR C 242 
AB9 2 5 N THR C 44  ? N THR C 246 O PHE C 170 ? O PHE C 372 
AB9 2 8 N VAL C 37  ? N VAL C 239 O TRP C 483 ? O TRP C 685 
AB9 3 4 N THR C 124 ? N THR C 326 O THR C 131 ? O THR C 333 
AB9 3 6 N LEU C 115 ? N LEU C 317 O PHE C 209 ? O PHE C 411 
AB9 3 7 N PHE C 106 ? N PHE C 308 O HIS C 221 ? O HIS C 423 
AB9 3 8 N LYS C 109 ? N LYS C 311 O GLU C 482 ? O GLU C 684 
AC1 1 2 N LYS C 56  ? N LYS C 258 O SER C 76  ? O SER C 278 
AC1 2 4 N TRP C 79  ? N TRP C 281 O TYR C 175 ? O TYR C 377 
AC1 2 6 N GLY C 80  ? N GLY C 282 O ILE C 447 ? O ILE C 649 
AC1 3 5 N VAL C 142 ? N VAL C 344 O GLN C 201 ? O GLN C 403 
AC1 3 6 N PHE C 143 ? N PHE C 345 O LEU C 446 ? O LEU C 648 
AC2 1 2 N ALA C 225 ? N ALA C 427 O ARG C 532 ? O ARG C 734 
AC3 1 2 N THR C 248 ? N THR C 450 O THR C 258 ? O THR C 460 
AC4 1 2 N SER C 281 ? N SER C 483 O GLN C 397 ? O GLN C 599 
AC5 1 2 N VAL C 287 ? N VAL C 489 O PHE C 333 ? O PHE C 535 
AC6 1 2 N PHE C 341 ? N PHE C 543 O MET C 357 ? O MET C 559 
AC7 1 2 N ALA C 418 ? N ALA C 620 O PHE C 436 ? O PHE C 638 
AC8 1 2 N LEU D 33  ? N LEU D 235 O ARG D 36  ? O ARG D 238 
AC8 2 5 N ALA D 46  ? N ALA D 248 O PHE D 170 ? O PHE D 372 
AC8 2 8 N VAL D 37  ? N VAL D 239 O TRP D 483 ? O TRP D 685 
AC8 3 4 N THR D 124 ? N THR D 326 O THR D 131 ? O THR D 333 
AC8 3 6 N LEU D 111 ? N LEU D 313 O TYR D 213 ? O TYR D 415 
AC8 3 7 N PHE D 106 ? N PHE D 308 O HIS D 221 ? O HIS D 423 
AC8 3 8 N GLN D 119 ? N GLN D 321 O THR D 474 ? O THR D 676 
AC9 1 2 N LYS D 56  ? N LYS D 258 O SER D 76  ? O SER D 278 
AC9 2 4 N TYR D 75  ? N TYR D 277 O TYR D 177 ? O TYR D 379 
AC9 2 6 N GLY D 80  ? N GLY D 282 O ILE D 447 ? O ILE D 649 
AC9 3 5 N VAL D 142 ? N VAL D 344 O GLN D 201 ? O GLN D 403 
AC9 3 6 N PHE D 143 ? N PHE D 345 O LEU D 446 ? O LEU D 648 
AD1 1 2 N THR D 248 ? N THR D 450 O THR D 258 ? O THR D 460 
AD2 1 2 N ILE D 277 ? N ILE D 479 O VAL D 404 ? O VAL D 606 
AD2 2 3 N TRP D 405 ? N TRP D 607 O GLY E 425 ? O GLY E 627 
AD3 1 2 N SER D 281 ? N SER D 483 O GLN D 397 ? O GLN D 599 
AD4 1 2 N VAL D 287 ? N VAL D 489 O PHE D 333 ? O PHE D 535 
AD5 1 2 O SER D 314 ? O SER D 516 N TRP D 307 ? N TRP D 509 
AD5 2 3 N SER D 306 ? N SER D 508 O GLN F 377 ? O GLN F 579 
AD5 3 4 N GLY F 376 ? N GLY F 578 O VAL F 394 ? O VAL F 596 
AD6 1 2 N PHE D 341 ? N PHE D 543 O MET D 357 ? O MET D 559 
AD7 1 2 O VAL D 394 ? O VAL D 596 N GLY D 376 ? N GLY D 578 
AD7 2 3 N GLN D 377 ? N GLN D 579 O SER E 306 ? O SER E 508 
AD7 3 4 N LEU E 309 ? N LEU E 511 O ARG E 312 ? O ARG E 514 
AD8 1 2 N ALA D 418 ? N ALA D 620 O PHE D 436 ? O PHE D 638 
AD9 1 2 N GLY D 425 ? N GLY D 627 O TRP F 405 ? O TRP F 607 
AD9 2 3 O VAL F 404 ? O VAL F 606 N ILE F 277 ? N ILE F 479 
AE1 1 2 N THR E 248 ? N THR E 450 O THR E 258 ? O THR E 460 
AE1 2 3 N PHE E 261 ? N PHE E 463 O VAL F 351 ? O VAL F 553 
AE2 1 2 N ILE E 277 ? N ILE E 479 O VAL E 404 ? O VAL E 606 
AE2 2 3 N TRP E 405 ? N TRP E 607 O GLY F 425 ? O GLY F 627 
AE3 1 2 N SER E 281 ? N SER E 483 O GLN E 397 ? O GLN E 599 
AE4 1 2 N VAL E 287 ? N VAL E 489 O PHE E 333 ? O PHE E 535 
AE5 1 2 O VAL E 394 ? O VAL E 596 N GLY E 376 ? N GLY E 578 
AE5 2 3 N GLN E 377 ? N GLN E 579 O SER F 306 ? O SER F 508 
AE5 3 4 N LEU F 309 ? N LEU F 511 O ARG F 312 ? O ARG F 514 
AE6 1 2 N ALA E 418 ? N ALA E 620 O MET E 438 ? O MET E 640 
AE7 1 2 N GLN F 31  ? N GLN F 233 O ILE F 38  ? O ILE F 240 
AE7 2 5 N THR F 44  ? N THR F 246 O PHE F 170 ? O PHE F 372 
AE7 2 8 N VAL F 37  ? N VAL F 239 O TRP F 483 ? O TRP F 685 
AE7 3 4 N GLU F 122 ? N GLU F 324 O ALA F 133 ? O ALA F 335 
AE7 3 6 N LEU F 115 ? N LEU F 317 O PHE F 209 ? O PHE F 411 
AE7 3 7 N PHE F 106 ? N PHE F 308 O HIS F 221 ? O HIS F 423 
AE7 3 8 N LYS F 109 ? N LYS F 311 O GLU F 482 ? O GLU F 684 
AE8 1 2 N LYS F 56  ? N LYS F 258 O SER F 76  ? O SER F 278 
AE8 2 3 N TRP F 79  ? N TRP F 281 O TYR F 175 ? O TYR F 377 
AE9 1 2 N VAL F 140 ? N VAL F 342 O LEU F 203 ? O LEU F 405 
AF1 1 2 N ALA F 225 ? N ALA F 427 O ARG F 532 ? O ARG F 734 
AF2 1 2 N THR F 248 ? N THR F 450 O THR F 258 ? O THR F 460 
AF3 1 2 N SER F 281 ? N SER F 483 O GLN F 397 ? O GLN F 599 
AF4 1 2 N VAL F 287 ? N VAL F 489 O PHE F 333 ? O PHE F 535 
AF5 1 2 N PHE F 341 ? N PHE F 543 O MET F 357 ? O MET F 559 
AF6 1 2 N ALA F 418 ? N ALA F 620 O MET F 438 ? O MET F 640 
AF7 1 2 N GLN G 4   ? N GLN H 22  O SER G 26  ? O SER H 44  
AF7 2 3 N LEU G 21  ? N LEU H 39  O LEU G 82  ? O LEU H 100 
AF7 3 4 O TYR G 81  ? O TYR H 99  N SER G 72  ? N SER H 90  
AF8 1 7 N VAL G 13  ? N VAL H 31  O THR G 128 ? O THR H 146 
AF8 2 3 N TRP G 37  ? N TRP H 55  O SER G 50  ? O SER H 68  
AF8 2 5 N VAL G 38  ? N VAL H 56  O TYR G 96  ? O TYR H 114 
AF8 3 4 N GLY G 51  ? N GLY H 69  O ASN G 60  ? O ASN H 78  
AF8 5 6 N LYS G 99  ? N LYS H 117 O VAL G 120 ? O VAL H 138 
AF8 5 7 N ALA G 93  ? N ALA H 111 O VAL G 127 ? O VAL H 145 
AF9 1 6 N ALA H 8   ? N ALA L 30  O THR H 107 ? O THR L 129 
AF9 2 3 N TRP H 34  ? N TRP L 56  O ILE H 47  ? O ILE L 69  
AF9 2 4 N TYR H 33  ? N TYR L 55  O ALA H 88  ? O ALA L 110 
AF9 4 5 N ASP H 91  ? N ASP L 113 O ASN H 97  ? O ASN L 119 
AF9 4 6 N TYR H 85  ? N TYR L 107 O THR H 104 ? O THR L 126 
AG1 1 2 N ILE H 18  ? N ILE L 40  O LEU H 72  ? O LEU L 94  
AG1 2 3 O ALA H 73  ? O ALA L 95  N SER H 62  ? N SER L 84  
# 
_pdbx_entry_details.entry_id                   9B7K 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1  1 OE1 C GLU 529 ? ? NZ  C LYS 567 ? ? 1.96 
2  1 OE2 C GLU 563 ? ? OH  C TYR 613 ? ? 2.00 
3  1 CD  D ARG 238 ? ? OE2 D GLU 684 ? ? 2.04 
4  1 OH  C TYR 415 ? ? O   C HIS 642 ? ? 2.06 
5  1 OH  A TYR 252 ? ? O   A ILE 374 ? ? 2.09 
6  1 OH  D TYR 415 ? ? O   D HIS 642 ? ? 2.10 
7  1 O   D SER 358 ? ? NE2 F GLN 442 ? ? 2.10 
8  1 OG  B SER 448 ? ? OD1 C ASN 552 ? ? 2.10 
9  1 OH  A TYR 415 ? ? O   A HIS 642 ? ? 2.10 
10 1 OD1 C ASP 285 ? ? CD2 C LEU 356 ? ? 2.11 
11 1 OH  D TYR 350 ? ? O   D PRO 643 ? ? 2.12 
12 1 OH  F TYR 415 ? ? O   F HIS 642 ? ? 2.16 
13 1 OH  C TYR 252 ? ? O   C ILE 374 ? ? 2.16 
14 1 CZ  D PHE 501 ? ? OE1 F GLN 585 ? ? 2.16 
15 1 NE  A ARG 550 ? ? OD2 C ASP 441 ? ? 2.17 
16 1 O   A SER 358 ? ? NE2 C GLN 442 ? ? 2.19 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ARG A 309 ? ? -173.60 146.62  
2  1 LYS A 311 ? ? -123.07 -56.21  
3  1 ASN A 329 ? ? 54.78   -118.63 
4  1 ILE A 618 ? ? -104.06 -61.77  
5  1 HIS A 630 ? ? 47.42   72.82   
6  1 ILE B 618 ? ? -100.19 -63.65  
7  1 HIS B 630 ? ? 51.52   72.92   
8  1 ASP C 231 ? ? 178.45  176.08  
9  1 ARG C 309 ? ? -173.77 145.56  
10 1 GLU C 563 ? ? -116.05 57.79   
11 1 ILE C 618 ? ? -94.01  -65.64  
12 1 HIS C 630 ? ? 50.78   72.83   
13 1 TYR C 731 ? ? -131.75 -57.75  
14 1 CYS D 230 ? ? -143.57 56.81   
15 1 SER D 268 ? ? 76.09   -3.62   
16 1 ARG D 309 ? ? -174.24 147.72  
17 1 LYS D 311 ? ? -128.71 -56.36  
18 1 ILE D 618 ? ? -95.75  -62.68  
19 1 HIS D 630 ? ? 44.66   70.54   
20 1 THR D 660 ? ? 78.26   -15.63  
21 1 ILE E 618 ? ? -100.96 -61.70  
22 1 HIS E 630 ? ? 49.66   71.15   
23 1 CYS F 230 ? ? -150.00 65.47   
24 1 ARG F 309 ? ? -173.91 145.89  
25 1 ASN F 329 ? ? 59.86   -128.47 
26 1 ILE F 618 ? ? -94.65  -63.00  
27 1 HIS F 630 ? ? 49.65   70.44   
28 1 TYR F 731 ? ? -132.07 -57.81  
29 1 TRP H 139 ? ? -116.18 -169.71 
30 1 ASN L 48  ? ? -101.41 -74.86  
31 1 ASN L 72  ? ? 70.73   -61.85  
32 1 ALA L 105 ? ? -167.30 -169.20 
# 
_pdbx_validate_peptide_omega.id               1 
_pdbx_validate_peptide_omega.PDB_model_num    1 
_pdbx_validate_peptide_omega.auth_comp_id_1   ASN 
_pdbx_validate_peptide_omega.auth_asym_id_1   A 
_pdbx_validate_peptide_omega.auth_seq_id_1    519 
_pdbx_validate_peptide_omega.PDB_ins_code_1   ? 
_pdbx_validate_peptide_omega.label_alt_id_1   ? 
_pdbx_validate_peptide_omega.auth_comp_id_2   PRO 
_pdbx_validate_peptide_omega.auth_asym_id_2   A 
_pdbx_validate_peptide_omega.auth_seq_id_2    520 
_pdbx_validate_peptide_omega.PDB_ins_code_2   ? 
_pdbx_validate_peptide_omega.label_alt_id_2   ? 
_pdbx_validate_peptide_omega.omega            -31.09 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9B7K 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9B7K 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.75 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               541473 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               'MULTIPLE SOURCES' 
_em_entity_assembly.type                 VIRUS 
_em_entity_assembly.name                 'Adeno-associated virus' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9B7K 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             2100 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_virus_entity.id                    1 
_em_virus_entity.virus_host_category   ? 
_em_virus_entity.virus_type            VIRION 
_em_virus_entity.virus_isolate         SEROTYPE 
_em_virus_entity.entity_assembly_id    1 
_em_virus_entity.enveloped             NO 
_em_virus_entity.empty                 NO 
_em_virus_entity.details               ? 
# 
_em_vitrification.entry_id              9B7K 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9B7K 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 203 ? A MET 1   
2   1 Y 1 A ALA 204 ? A ALA 2   
3   1 Y 1 A SER 205 ? A SER 3   
4   1 Y 1 A GLY 206 ? A GLY 4   
5   1 Y 1 A GLY 207 ? A GLY 5   
6   1 Y 1 A GLY 208 ? A GLY 6   
7   1 Y 1 A ALA 209 ? A ALA 7   
8   1 Y 1 A PRO 210 ? A PRO 8   
9   1 Y 1 A VAL 211 ? A VAL 9   
10  1 Y 1 A ALA 212 ? A ALA 10  
11  1 Y 1 A ASP 213 ? A ASP 11  
12  1 Y 1 A ASN 214 ? A ASN 12  
13  1 Y 1 A ASN 215 ? A ASN 13  
14  1 Y 1 A GLU 216 ? A GLU 14  
15  1 Y 1 A GLY 217 ? A GLY 15  
16  1 Y 1 A ALA 218 ? A ALA 16  
17  1 Y 1 A ASP 219 ? A ASP 17  
18  1 Y 1 A LEU 439 ? A LEU 237 
19  1 Y 1 A ILE 440 ? A ILE 238 
20  1 Y 1 A ASP 441 ? A ASP 239 
21  1 Y 1 A LYS 689 ? A LYS 487 
22  1 Y 1 A GLU 690 ? A GLU 488 
23  1 Y 1 A ASN 691 ? A ASN 489 
24  1 Y 1 A SER 692 ? A SER 490 
25  1 Y 1 A LYS 693 ? A LYS 491 
26  1 Y 1 A ARG 694 ? A ARG 492 
27  1 Y 1 A TRP 695 ? A TRP 493 
28  1 Y 1 A ASN 696 ? A ASN 494 
29  1 Y 1 A PRO 697 ? A PRO 495 
30  1 Y 1 A GLU 698 ? A GLU 496 
31  1 Y 1 A ILE 699 ? A ILE 497 
32  1 Y 1 A GLN 700 ? A GLN 498 
33  1 Y 1 A TYR 701 ? A TYR 499 
34  1 Y 1 A THR 702 ? A THR 500 
35  1 Y 1 A SER 703 ? A SER 501 
36  1 Y 1 A ASN 704 ? A ASN 502 
37  1 Y 1 A TYR 705 ? A TYR 503 
38  1 Y 1 A TYR 706 ? A TYR 504 
39  1 Y 1 A LYS 707 ? A LYS 505 
40  1 Y 1 A SER 708 ? A SER 506 
41  1 Y 1 A ASN 709 ? A ASN 507 
42  1 Y 1 A ASN 710 ? A ASN 508 
43  1 Y 1 A VAL 711 ? A VAL 509 
44  1 Y 1 A GLU 712 ? A GLU 510 
45  1 Y 1 A PHE 713 ? A PHE 511 
46  1 Y 1 A ALA 714 ? A ALA 512 
47  1 Y 1 A VAL 715 ? A VAL 513 
48  1 Y 1 A ASN 716 ? A ASN 514 
49  1 Y 1 A THR 717 ? A THR 515 
50  1 Y 1 A GLU 718 ? A GLU 516 
51  1 Y 1 A GLY 719 ? A GLY 517 
52  1 Y 1 A VAL 720 ? A VAL 518 
53  1 Y 1 A TYR 721 ? A TYR 519 
54  1 Y 1 A SER 722 ? A SER 520 
55  1 Y 1 A GLU 723 ? A GLU 521 
56  1 Y 1 A PRO 724 ? A PRO 522 
57  1 Y 1 A ARG 725 ? A ARG 523 
58  1 Y 1 A PRO 726 ? A PRO 524 
59  1 Y 1 A ILE 727 ? A ILE 525 
60  1 Y 1 A GLY 728 ? A GLY 526 
61  1 Y 1 A THR 729 ? A THR 527 
62  1 Y 1 A ARG 730 ? A ARG 528 
63  1 Y 1 A TYR 731 ? A TYR 529 
64  1 Y 1 A LEU 732 ? A LEU 530 
65  1 Y 1 A THR 733 ? A THR 531 
66  1 Y 1 A ARG 734 ? A ARG 532 
67  1 Y 1 A ASN 735 ? A ASN 533 
68  1 Y 1 A LEU 736 ? A LEU 534 
69  1 Y 1 B MET 203 ? B MET 1   
70  1 Y 1 B ALA 204 ? B ALA 2   
71  1 Y 1 B SER 205 ? B SER 3   
72  1 Y 1 B GLY 206 ? B GLY 4   
73  1 Y 1 B GLY 207 ? B GLY 5   
74  1 Y 1 B GLY 208 ? B GLY 6   
75  1 Y 1 B ALA 209 ? B ALA 7   
76  1 Y 1 B PRO 210 ? B PRO 8   
77  1 Y 1 B VAL 211 ? B VAL 9   
78  1 Y 1 B ALA 212 ? B ALA 10  
79  1 Y 1 B ASP 213 ? B ASP 11  
80  1 Y 1 B ASN 214 ? B ASN 12  
81  1 Y 1 B ASN 215 ? B ASN 13  
82  1 Y 1 B GLU 216 ? B GLU 14  
83  1 Y 1 B GLY 217 ? B GLY 15  
84  1 Y 1 B ALA 218 ? B ALA 16  
85  1 Y 1 B ASP 219 ? B ASP 17  
86  1 Y 1 B GLY 220 ? B GLY 18  
87  1 Y 1 B VAL 221 ? B VAL 19  
88  1 Y 1 B GLY 222 ? B GLY 20  
89  1 Y 1 B SER 223 ? B SER 21  
90  1 Y 1 B SER 224 ? B SER 22  
91  1 Y 1 B SER 225 ? B SER 23  
92  1 Y 1 B GLY 226 ? B GLY 24  
93  1 Y 1 B ASN 227 ? B ASN 25  
94  1 Y 1 B TRP 228 ? B TRP 26  
95  1 Y 1 B HIS 229 ? B HIS 27  
96  1 Y 1 B CYS 230 ? B CYS 28  
97  1 Y 1 B ASP 231 ? B ASP 29  
98  1 Y 1 B SER 232 ? B SER 30  
99  1 Y 1 B GLN 233 ? B GLN 31  
100 1 Y 1 B TRP 234 ? B TRP 32  
101 1 Y 1 B LEU 235 ? B LEU 33  
102 1 Y 1 B GLY 236 ? B GLY 34  
103 1 Y 1 B ASP 237 ? B ASP 35  
104 1 Y 1 B ARG 238 ? B ARG 36  
105 1 Y 1 B VAL 239 ? B VAL 37  
106 1 Y 1 B ILE 240 ? B ILE 38  
107 1 Y 1 B THR 241 ? B THR 39  
108 1 Y 1 B THR 242 ? B THR 40  
109 1 Y 1 B SER 243 ? B SER 41  
110 1 Y 1 B THR 244 ? B THR 42  
111 1 Y 1 B ARG 245 ? B ARG 43  
112 1 Y 1 B THR 246 ? B THR 44  
113 1 Y 1 B TRP 247 ? B TRP 45  
114 1 Y 1 B ALA 248 ? B ALA 46  
115 1 Y 1 B LEU 249 ? B LEU 47  
116 1 Y 1 B PRO 250 ? B PRO 48  
117 1 Y 1 B THR 251 ? B THR 49  
118 1 Y 1 B TYR 252 ? B TYR 50  
119 1 Y 1 B ASN 253 ? B ASN 51  
120 1 Y 1 B ASN 254 ? B ASN 52  
121 1 Y 1 B HIS 255 ? B HIS 53  
122 1 Y 1 B LEU 256 ? B LEU 54  
123 1 Y 1 B TYR 257 ? B TYR 55  
124 1 Y 1 B LYS 258 ? B LYS 56  
125 1 Y 1 B GLN 259 ? B GLN 57  
126 1 Y 1 B ILE 260 ? B ILE 58  
127 1 Y 1 B SER 261 ? B SER 59  
128 1 Y 1 B ASN 262 ? B ASN 60  
129 1 Y 1 B SER 263 ? B SER 61  
130 1 Y 1 B THR 264 ? B THR 62  
131 1 Y 1 B SER 265 ? B SER 63  
132 1 Y 1 B GLY 266 ? B GLY 64  
133 1 Y 1 B GLY 267 ? B GLY 65  
134 1 Y 1 B SER 268 ? B SER 66  
135 1 Y 1 B SER 269 ? B SER 67  
136 1 Y 1 B ASN 270 ? B ASN 68  
137 1 Y 1 B ASP 271 ? B ASP 69  
138 1 Y 1 B ASN 272 ? B ASN 70  
139 1 Y 1 B ALA 273 ? B ALA 71  
140 1 Y 1 B TYR 274 ? B TYR 72  
141 1 Y 1 B PHE 275 ? B PHE 73  
142 1 Y 1 B GLY 276 ? B GLY 74  
143 1 Y 1 B TYR 277 ? B TYR 75  
144 1 Y 1 B SER 278 ? B SER 76  
145 1 Y 1 B THR 279 ? B THR 77  
146 1 Y 1 B PRO 280 ? B PRO 78  
147 1 Y 1 B TRP 281 ? B TRP 79  
148 1 Y 1 B GLY 282 ? B GLY 80  
149 1 Y 1 B TYR 283 ? B TYR 81  
150 1 Y 1 B PHE 284 ? B PHE 82  
151 1 Y 1 B ASP 285 ? B ASP 83  
152 1 Y 1 B PHE 286 ? B PHE 84  
153 1 Y 1 B ASN 287 ? B ASN 85  
154 1 Y 1 B ARG 288 ? B ARG 86  
155 1 Y 1 B PHE 289 ? B PHE 87  
156 1 Y 1 B HIS 290 ? B HIS 88  
157 1 Y 1 B CYS 291 ? B CYS 89  
158 1 Y 1 B HIS 292 ? B HIS 90  
159 1 Y 1 B PHE 293 ? B PHE 91  
160 1 Y 1 B SER 294 ? B SER 92  
161 1 Y 1 B PRO 295 ? B PRO 93  
162 1 Y 1 B ARG 296 ? B ARG 94  
163 1 Y 1 B ASP 297 ? B ASP 95  
164 1 Y 1 B TRP 298 ? B TRP 96  
165 1 Y 1 B GLN 299 ? B GLN 97  
166 1 Y 1 B ARG 300 ? B ARG 98  
167 1 Y 1 B LEU 301 ? B LEU 99  
168 1 Y 1 B ILE 302 ? B ILE 100 
169 1 Y 1 B ASN 303 ? B ASN 101 
170 1 Y 1 B ASN 304 ? B ASN 102 
171 1 Y 1 B ASN 305 ? B ASN 103 
172 1 Y 1 B TRP 306 ? B TRP 104 
173 1 Y 1 B GLY 307 ? B GLY 105 
174 1 Y 1 B PHE 308 ? B PHE 106 
175 1 Y 1 B ARG 309 ? B ARG 107 
176 1 Y 1 B PRO 310 ? B PRO 108 
177 1 Y 1 B LYS 311 ? B LYS 109 
178 1 Y 1 B ARG 312 ? B ARG 110 
179 1 Y 1 B LEU 313 ? B LEU 111 
180 1 Y 1 B ASN 314 ? B ASN 112 
181 1 Y 1 B PHE 315 ? B PHE 113 
182 1 Y 1 B LYS 316 ? B LYS 114 
183 1 Y 1 B LEU 317 ? B LEU 115 
184 1 Y 1 B PHE 318 ? B PHE 116 
185 1 Y 1 B ASN 319 ? B ASN 117 
186 1 Y 1 B ILE 320 ? B ILE 118 
187 1 Y 1 B GLN 321 ? B GLN 119 
188 1 Y 1 B VAL 322 ? B VAL 120 
189 1 Y 1 B LYS 323 ? B LYS 121 
190 1 Y 1 B GLU 324 ? B GLU 122 
191 1 Y 1 B VAL 325 ? B VAL 123 
192 1 Y 1 B THR 326 ? B THR 124 
193 1 Y 1 B ASP 327 ? B ASP 125 
194 1 Y 1 B ASN 328 ? B ASN 126 
195 1 Y 1 B ASN 329 ? B ASN 127 
196 1 Y 1 B GLY 330 ? B GLY 128 
197 1 Y 1 B VAL 331 ? B VAL 129 
198 1 Y 1 B LYS 332 ? B LYS 130 
199 1 Y 1 B THR 333 ? B THR 131 
200 1 Y 1 B ILE 334 ? B ILE 132 
201 1 Y 1 B ALA 335 ? B ALA 133 
202 1 Y 1 B ASN 336 ? B ASN 134 
203 1 Y 1 B ASN 337 ? B ASN 135 
204 1 Y 1 B LEU 338 ? B LEU 136 
205 1 Y 1 B THR 339 ? B THR 137 
206 1 Y 1 B SER 340 ? B SER 138 
207 1 Y 1 B THR 341 ? B THR 139 
208 1 Y 1 B VAL 342 ? B VAL 140 
209 1 Y 1 B GLN 343 ? B GLN 141 
210 1 Y 1 B VAL 344 ? B VAL 142 
211 1 Y 1 B PHE 345 ? B PHE 143 
212 1 Y 1 B THR 346 ? B THR 144 
213 1 Y 1 B ASP 347 ? B ASP 145 
214 1 Y 1 B SER 348 ? B SER 146 
215 1 Y 1 B ASP 349 ? B ASP 147 
216 1 Y 1 B TYR 350 ? B TYR 148 
217 1 Y 1 B GLN 351 ? B GLN 149 
218 1 Y 1 B LEU 352 ? B LEU 150 
219 1 Y 1 B PRO 353 ? B PRO 151 
220 1 Y 1 B TYR 354 ? B TYR 152 
221 1 Y 1 B VAL 355 ? B VAL 153 
222 1 Y 1 B LEU 356 ? B LEU 154 
223 1 Y 1 B GLY 357 ? B GLY 155 
224 1 Y 1 B SER 358 ? B SER 156 
225 1 Y 1 B ALA 359 ? B ALA 157 
226 1 Y 1 B HIS 360 ? B HIS 158 
227 1 Y 1 B GLU 361 ? B GLU 159 
228 1 Y 1 B GLY 362 ? B GLY 160 
229 1 Y 1 B CYS 363 ? B CYS 161 
230 1 Y 1 B LEU 364 ? B LEU 162 
231 1 Y 1 B PRO 365 ? B PRO 163 
232 1 Y 1 B PRO 366 ? B PRO 164 
233 1 Y 1 B PHE 367 ? B PHE 165 
234 1 Y 1 B PRO 368 ? B PRO 166 
235 1 Y 1 B ALA 369 ? B ALA 167 
236 1 Y 1 B ASP 370 ? B ASP 168 
237 1 Y 1 B VAL 371 ? B VAL 169 
238 1 Y 1 B PHE 372 ? B PHE 170 
239 1 Y 1 B MET 373 ? B MET 171 
240 1 Y 1 B ILE 374 ? B ILE 172 
241 1 Y 1 B PRO 375 ? B PRO 173 
242 1 Y 1 B GLN 376 ? B GLN 174 
243 1 Y 1 B TYR 377 ? B TYR 175 
244 1 Y 1 B GLY 378 ? B GLY 176 
245 1 Y 1 B TYR 379 ? B TYR 177 
246 1 Y 1 B LEU 380 ? B LEU 178 
247 1 Y 1 B THR 381 ? B THR 179 
248 1 Y 1 B LEU 382 ? B LEU 180 
249 1 Y 1 B ASN 383 ? B ASN 181 
250 1 Y 1 B ASP 384 ? B ASP 182 
251 1 Y 1 B GLY 385 ? B GLY 183 
252 1 Y 1 B SER 386 ? B SER 184 
253 1 Y 1 B GLN 387 ? B GLN 185 
254 1 Y 1 B ALA 388 ? B ALA 186 
255 1 Y 1 B VAL 389 ? B VAL 187 
256 1 Y 1 B GLY 390 ? B GLY 188 
257 1 Y 1 B ARG 391 ? B ARG 189 
258 1 Y 1 B SER 392 ? B SER 190 
259 1 Y 1 B SER 393 ? B SER 191 
260 1 Y 1 B PHE 394 ? B PHE 192 
261 1 Y 1 B TYR 395 ? B TYR 193 
262 1 Y 1 B CYS 396 ? B CYS 194 
263 1 Y 1 B LEU 397 ? B LEU 195 
264 1 Y 1 B GLU 398 ? B GLU 196 
265 1 Y 1 B TYR 399 ? B TYR 197 
266 1 Y 1 B PHE 400 ? B PHE 198 
267 1 Y 1 B PRO 401 ? B PRO 199 
268 1 Y 1 B SER 402 ? B SER 200 
269 1 Y 1 B GLN 403 ? B GLN 201 
270 1 Y 1 B MET 404 ? B MET 202 
271 1 Y 1 B LEU 405 ? B LEU 203 
272 1 Y 1 B ARG 406 ? B ARG 204 
273 1 Y 1 B THR 407 ? B THR 205 
274 1 Y 1 B GLY 408 ? B GLY 206 
275 1 Y 1 B ASN 409 ? B ASN 207 
276 1 Y 1 B ASN 410 ? B ASN 208 
277 1 Y 1 B PHE 411 ? B PHE 209 
278 1 Y 1 B GLN 412 ? B GLN 210 
279 1 Y 1 B PHE 413 ? B PHE 211 
280 1 Y 1 B SER 414 ? B SER 212 
281 1 Y 1 B TYR 415 ? B TYR 213 
282 1 Y 1 B GLU 416 ? B GLU 214 
283 1 Y 1 B GLY 544 ? B GLY 342 
284 1 Y 1 B LYS 545 ? B LYS 343 
285 1 Y 1 B GLN 546 ? B GLN 344 
286 1 Y 1 B GLY 547 ? B GLY 345 
287 1 Y 1 B THR 548 ? B THR 346 
288 1 Y 1 B GLY 549 ? B GLY 347 
289 1 Y 1 B ARG 550 ? B ARG 348 
290 1 Y 1 B ASP 551 ? B ASP 349 
291 1 Y 1 B ASN 552 ? B ASN 350 
292 1 Y 1 B VAL 553 ? B VAL 351 
293 1 Y 1 B ASP 554 ? B ASP 352 
294 1 Y 1 B ALA 555 ? B ALA 353 
295 1 Y 1 B ASP 556 ? B ASP 354 
296 1 Y 1 B LYS 557 ? B LYS 355 
297 1 Y 1 B PRO 645 ? B PRO 443 
298 1 Y 1 B GLN 646 ? B GLN 444 
299 1 Y 1 B ILE 647 ? B ILE 445 
300 1 Y 1 B LEU 648 ? B LEU 446 
301 1 Y 1 B ILE 649 ? B ILE 447 
302 1 Y 1 B LYS 650 ? B LYS 448 
303 1 Y 1 B ASN 651 ? B ASN 449 
304 1 Y 1 B THR 652 ? B THR 450 
305 1 Y 1 B PRO 653 ? B PRO 451 
306 1 Y 1 B VAL 654 ? B VAL 452 
307 1 Y 1 B PRO 655 ? B PRO 453 
308 1 Y 1 B ALA 656 ? B ALA 454 
309 1 Y 1 B ASP 657 ? B ASP 455 
310 1 Y 1 B PRO 658 ? B PRO 456 
311 1 Y 1 B PRO 659 ? B PRO 457 
312 1 Y 1 B THR 660 ? B THR 458 
313 1 Y 1 B ALA 661 ? B ALA 459 
314 1 Y 1 B PHE 662 ? B PHE 460 
315 1 Y 1 B ASN 663 ? B ASN 461 
316 1 Y 1 B LYS 664 ? B LYS 462 
317 1 Y 1 B ASP 665 ? B ASP 463 
318 1 Y 1 B LYS 666 ? B LYS 464 
319 1 Y 1 B LEU 667 ? B LEU 465 
320 1 Y 1 B ASN 668 ? B ASN 466 
321 1 Y 1 B SER 669 ? B SER 467 
322 1 Y 1 B PHE 670 ? B PHE 468 
323 1 Y 1 B ILE 671 ? B ILE 469 
324 1 Y 1 B THR 672 ? B THR 470 
325 1 Y 1 B GLN 673 ? B GLN 471 
326 1 Y 1 B TYR 674 ? B TYR 472 
327 1 Y 1 B SER 675 ? B SER 473 
328 1 Y 1 B THR 676 ? B THR 474 
329 1 Y 1 B GLY 677 ? B GLY 475 
330 1 Y 1 B GLN 678 ? B GLN 476 
331 1 Y 1 B VAL 679 ? B VAL 477 
332 1 Y 1 B SER 680 ? B SER 478 
333 1 Y 1 B VAL 681 ? B VAL 479 
334 1 Y 1 B GLU 682 ? B GLU 480 
335 1 Y 1 B ILE 683 ? B ILE 481 
336 1 Y 1 B GLU 684 ? B GLU 482 
337 1 Y 1 B TRP 685 ? B TRP 483 
338 1 Y 1 B GLU 686 ? B GLU 484 
339 1 Y 1 B LEU 687 ? B LEU 485 
340 1 Y 1 B GLN 688 ? B GLN 486 
341 1 Y 1 B LYS 689 ? B LYS 487 
342 1 Y 1 B GLU 690 ? B GLU 488 
343 1 Y 1 B ASN 691 ? B ASN 489 
344 1 Y 1 B SER 692 ? B SER 490 
345 1 Y 1 B LYS 693 ? B LYS 491 
346 1 Y 1 B ARG 694 ? B ARG 492 
347 1 Y 1 B TRP 695 ? B TRP 493 
348 1 Y 1 B ASN 696 ? B ASN 494 
349 1 Y 1 B PRO 697 ? B PRO 495 
350 1 Y 1 B GLU 698 ? B GLU 496 
351 1 Y 1 B ILE 699 ? B ILE 497 
352 1 Y 1 B GLN 700 ? B GLN 498 
353 1 Y 1 B TYR 701 ? B TYR 499 
354 1 Y 1 B THR 702 ? B THR 500 
355 1 Y 1 B SER 703 ? B SER 501 
356 1 Y 1 B ASN 704 ? B ASN 502 
357 1 Y 1 B TYR 705 ? B TYR 503 
358 1 Y 1 B TYR 706 ? B TYR 504 
359 1 Y 1 B LYS 707 ? B LYS 505 
360 1 Y 1 B SER 708 ? B SER 506 
361 1 Y 1 B ASN 709 ? B ASN 507 
362 1 Y 1 B ASN 710 ? B ASN 508 
363 1 Y 1 B VAL 711 ? B VAL 509 
364 1 Y 1 B GLU 712 ? B GLU 510 
365 1 Y 1 B PHE 713 ? B PHE 511 
366 1 Y 1 B ALA 714 ? B ALA 512 
367 1 Y 1 B VAL 715 ? B VAL 513 
368 1 Y 1 B ASN 716 ? B ASN 514 
369 1 Y 1 B THR 717 ? B THR 515 
370 1 Y 1 B GLU 718 ? B GLU 516 
371 1 Y 1 B GLY 719 ? B GLY 517 
372 1 Y 1 B VAL 720 ? B VAL 518 
373 1 Y 1 B TYR 721 ? B TYR 519 
374 1 Y 1 B SER 722 ? B SER 520 
375 1 Y 1 B GLU 723 ? B GLU 521 
376 1 Y 1 B PRO 724 ? B PRO 522 
377 1 Y 1 B ARG 725 ? B ARG 523 
378 1 Y 1 B PRO 726 ? B PRO 524 
379 1 Y 1 B ILE 727 ? B ILE 525 
380 1 Y 1 B GLY 728 ? B GLY 526 
381 1 Y 1 B THR 729 ? B THR 527 
382 1 Y 1 B ARG 730 ? B ARG 528 
383 1 Y 1 B TYR 731 ? B TYR 529 
384 1 Y 1 B LEU 732 ? B LEU 530 
385 1 Y 1 B THR 733 ? B THR 531 
386 1 Y 1 B ARG 734 ? B ARG 532 
387 1 Y 1 B ASN 735 ? B ASN 533 
388 1 Y 1 B LEU 736 ? B LEU 534 
389 1 Y 1 C MET 203 ? C MET 1   
390 1 Y 1 C ALA 204 ? C ALA 2   
391 1 Y 1 C SER 205 ? C SER 3   
392 1 Y 1 C GLY 206 ? C GLY 4   
393 1 Y 1 C GLY 207 ? C GLY 5   
394 1 Y 1 C GLY 208 ? C GLY 6   
395 1 Y 1 C ALA 209 ? C ALA 7   
396 1 Y 1 C PRO 210 ? C PRO 8   
397 1 Y 1 C VAL 211 ? C VAL 9   
398 1 Y 1 C ALA 212 ? C ALA 10  
399 1 Y 1 C ASP 213 ? C ASP 11  
400 1 Y 1 C ASN 214 ? C ASN 12  
401 1 Y 1 C ASN 215 ? C ASN 13  
402 1 Y 1 C GLU 216 ? C GLU 14  
403 1 Y 1 C GLY 217 ? C GLY 15  
404 1 Y 1 C ALA 218 ? C ALA 16  
405 1 Y 1 C ALA 656 ? C ALA 454 
406 1 Y 1 C ASP 657 ? C ASP 455 
407 1 Y 1 C PRO 658 ? C PRO 456 
408 1 Y 1 C PRO 659 ? C PRO 457 
409 1 Y 1 C THR 660 ? C THR 458 
410 1 Y 1 C ALA 661 ? C ALA 459 
411 1 Y 1 C PHE 662 ? C PHE 460 
412 1 Y 1 C ASN 663 ? C ASN 461 
413 1 Y 1 C LYS 664 ? C LYS 462 
414 1 Y 1 C ASP 665 ? C ASP 463 
415 1 Y 1 C LYS 666 ? C LYS 464 
416 1 Y 1 D MET 203 ? D MET 1   
417 1 Y 1 D ALA 204 ? D ALA 2   
418 1 Y 1 D SER 205 ? D SER 3   
419 1 Y 1 D GLY 206 ? D GLY 4   
420 1 Y 1 D GLY 207 ? D GLY 5   
421 1 Y 1 D GLY 208 ? D GLY 6   
422 1 Y 1 D ALA 209 ? D ALA 7   
423 1 Y 1 D PRO 210 ? D PRO 8   
424 1 Y 1 D VAL 211 ? D VAL 9   
425 1 Y 1 D ALA 212 ? D ALA 10  
426 1 Y 1 D ASP 213 ? D ASP 11  
427 1 Y 1 D ASN 214 ? D ASN 12  
428 1 Y 1 D ASN 215 ? D ASN 13  
429 1 Y 1 D GLU 216 ? D GLU 14  
430 1 Y 1 D GLY 217 ? D GLY 15  
431 1 Y 1 D ALA 218 ? D ALA 16  
432 1 Y 1 D LEU 439 ? D LEU 237 
433 1 Y 1 D ILE 440 ? D ILE 238 
434 1 Y 1 D ASP 441 ? D ASP 239 
435 1 Y 1 D LYS 689 ? D LYS 487 
436 1 Y 1 D GLU 690 ? D GLU 488 
437 1 Y 1 D ASN 691 ? D ASN 489 
438 1 Y 1 D SER 692 ? D SER 490 
439 1 Y 1 D LYS 693 ? D LYS 491 
440 1 Y 1 D ARG 694 ? D ARG 492 
441 1 Y 1 D TRP 695 ? D TRP 493 
442 1 Y 1 D ASN 696 ? D ASN 494 
443 1 Y 1 D PRO 697 ? D PRO 495 
444 1 Y 1 D GLU 698 ? D GLU 496 
445 1 Y 1 D ILE 699 ? D ILE 497 
446 1 Y 1 D GLN 700 ? D GLN 498 
447 1 Y 1 D TYR 701 ? D TYR 499 
448 1 Y 1 D THR 702 ? D THR 500 
449 1 Y 1 D SER 703 ? D SER 501 
450 1 Y 1 D ASN 704 ? D ASN 502 
451 1 Y 1 D TYR 705 ? D TYR 503 
452 1 Y 1 D TYR 706 ? D TYR 504 
453 1 Y 1 D LYS 707 ? D LYS 505 
454 1 Y 1 D SER 708 ? D SER 506 
455 1 Y 1 D ASN 709 ? D ASN 507 
456 1 Y 1 D ASN 710 ? D ASN 508 
457 1 Y 1 D VAL 711 ? D VAL 509 
458 1 Y 1 D GLU 712 ? D GLU 510 
459 1 Y 1 D PHE 713 ? D PHE 511 
460 1 Y 1 D ALA 714 ? D ALA 512 
461 1 Y 1 D VAL 715 ? D VAL 513 
462 1 Y 1 D ASN 716 ? D ASN 514 
463 1 Y 1 D THR 717 ? D THR 515 
464 1 Y 1 D GLU 718 ? D GLU 516 
465 1 Y 1 D GLY 719 ? D GLY 517 
466 1 Y 1 D VAL 720 ? D VAL 518 
467 1 Y 1 D TYR 721 ? D TYR 519 
468 1 Y 1 D SER 722 ? D SER 520 
469 1 Y 1 D GLU 723 ? D GLU 521 
470 1 Y 1 D PRO 724 ? D PRO 522 
471 1 Y 1 D ARG 725 ? D ARG 523 
472 1 Y 1 D PRO 726 ? D PRO 524 
473 1 Y 1 D ILE 727 ? D ILE 525 
474 1 Y 1 D GLY 728 ? D GLY 526 
475 1 Y 1 D THR 729 ? D THR 527 
476 1 Y 1 D ARG 730 ? D ARG 528 
477 1 Y 1 D TYR 731 ? D TYR 529 
478 1 Y 1 D LEU 732 ? D LEU 530 
479 1 Y 1 D THR 733 ? D THR 531 
480 1 Y 1 D ARG 734 ? D ARG 532 
481 1 Y 1 D ASN 735 ? D ASN 533 
482 1 Y 1 D LEU 736 ? D LEU 534 
483 1 Y 1 E MET 203 ? E MET 1   
484 1 Y 1 E ALA 204 ? E ALA 2   
485 1 Y 1 E SER 205 ? E SER 3   
486 1 Y 1 E GLY 206 ? E GLY 4   
487 1 Y 1 E GLY 207 ? E GLY 5   
488 1 Y 1 E GLY 208 ? E GLY 6   
489 1 Y 1 E ALA 209 ? E ALA 7   
490 1 Y 1 E PRO 210 ? E PRO 8   
491 1 Y 1 E VAL 211 ? E VAL 9   
492 1 Y 1 E ALA 212 ? E ALA 10  
493 1 Y 1 E ASP 213 ? E ASP 11  
494 1 Y 1 E ASN 214 ? E ASN 12  
495 1 Y 1 E ASN 215 ? E ASN 13  
496 1 Y 1 E GLU 216 ? E GLU 14  
497 1 Y 1 E GLY 217 ? E GLY 15  
498 1 Y 1 E ALA 218 ? E ALA 16  
499 1 Y 1 E ASP 219 ? E ASP 17  
500 1 Y 1 E GLY 220 ? E GLY 18  
501 1 Y 1 E VAL 221 ? E VAL 19  
502 1 Y 1 E GLY 222 ? E GLY 20  
503 1 Y 1 E SER 223 ? E SER 21  
504 1 Y 1 E SER 224 ? E SER 22  
505 1 Y 1 E SER 225 ? E SER 23  
506 1 Y 1 E GLY 226 ? E GLY 24  
507 1 Y 1 E ASN 227 ? E ASN 25  
508 1 Y 1 E TRP 228 ? E TRP 26  
509 1 Y 1 E HIS 229 ? E HIS 27  
510 1 Y 1 E CYS 230 ? E CYS 28  
511 1 Y 1 E ASP 231 ? E ASP 29  
512 1 Y 1 E SER 232 ? E SER 30  
513 1 Y 1 E GLN 233 ? E GLN 31  
514 1 Y 1 E TRP 234 ? E TRP 32  
515 1 Y 1 E LEU 235 ? E LEU 33  
516 1 Y 1 E GLY 236 ? E GLY 34  
517 1 Y 1 E ASP 237 ? E ASP 35  
518 1 Y 1 E ARG 238 ? E ARG 36  
519 1 Y 1 E VAL 239 ? E VAL 37  
520 1 Y 1 E ILE 240 ? E ILE 38  
521 1 Y 1 E THR 241 ? E THR 39  
522 1 Y 1 E THR 242 ? E THR 40  
523 1 Y 1 E SER 243 ? E SER 41  
524 1 Y 1 E THR 244 ? E THR 42  
525 1 Y 1 E ARG 245 ? E ARG 43  
526 1 Y 1 E THR 246 ? E THR 44  
527 1 Y 1 E TRP 247 ? E TRP 45  
528 1 Y 1 E ALA 248 ? E ALA 46  
529 1 Y 1 E LEU 249 ? E LEU 47  
530 1 Y 1 E PRO 250 ? E PRO 48  
531 1 Y 1 E THR 251 ? E THR 49  
532 1 Y 1 E TYR 252 ? E TYR 50  
533 1 Y 1 E ASN 253 ? E ASN 51  
534 1 Y 1 E ASN 254 ? E ASN 52  
535 1 Y 1 E HIS 255 ? E HIS 53  
536 1 Y 1 E LEU 256 ? E LEU 54  
537 1 Y 1 E TYR 257 ? E TYR 55  
538 1 Y 1 E LYS 258 ? E LYS 56  
539 1 Y 1 E GLN 259 ? E GLN 57  
540 1 Y 1 E ILE 260 ? E ILE 58  
541 1 Y 1 E SER 261 ? E SER 59  
542 1 Y 1 E ASN 262 ? E ASN 60  
543 1 Y 1 E SER 263 ? E SER 61  
544 1 Y 1 E THR 264 ? E THR 62  
545 1 Y 1 E SER 265 ? E SER 63  
546 1 Y 1 E GLY 266 ? E GLY 64  
547 1 Y 1 E GLY 267 ? E GLY 65  
548 1 Y 1 E SER 268 ? E SER 66  
549 1 Y 1 E SER 269 ? E SER 67  
550 1 Y 1 E ASN 270 ? E ASN 68  
551 1 Y 1 E ASP 271 ? E ASP 69  
552 1 Y 1 E ASN 272 ? E ASN 70  
553 1 Y 1 E ALA 273 ? E ALA 71  
554 1 Y 1 E TYR 274 ? E TYR 72  
555 1 Y 1 E PHE 275 ? E PHE 73  
556 1 Y 1 E GLY 276 ? E GLY 74  
557 1 Y 1 E TYR 277 ? E TYR 75  
558 1 Y 1 E SER 278 ? E SER 76  
559 1 Y 1 E THR 279 ? E THR 77  
560 1 Y 1 E PRO 280 ? E PRO 78  
561 1 Y 1 E TRP 281 ? E TRP 79  
562 1 Y 1 E GLY 282 ? E GLY 80  
563 1 Y 1 E TYR 283 ? E TYR 81  
564 1 Y 1 E PHE 284 ? E PHE 82  
565 1 Y 1 E ASP 285 ? E ASP 83  
566 1 Y 1 E PHE 286 ? E PHE 84  
567 1 Y 1 E ASN 287 ? E ASN 85  
568 1 Y 1 E ARG 288 ? E ARG 86  
569 1 Y 1 E PHE 289 ? E PHE 87  
570 1 Y 1 E HIS 290 ? E HIS 88  
571 1 Y 1 E CYS 291 ? E CYS 89  
572 1 Y 1 E HIS 292 ? E HIS 90  
573 1 Y 1 E PHE 293 ? E PHE 91  
574 1 Y 1 E SER 294 ? E SER 92  
575 1 Y 1 E PRO 295 ? E PRO 93  
576 1 Y 1 E ARG 296 ? E ARG 94  
577 1 Y 1 E ASP 297 ? E ASP 95  
578 1 Y 1 E TRP 298 ? E TRP 96  
579 1 Y 1 E GLN 299 ? E GLN 97  
580 1 Y 1 E ARG 300 ? E ARG 98  
581 1 Y 1 E LEU 301 ? E LEU 99  
582 1 Y 1 E ILE 302 ? E ILE 100 
583 1 Y 1 E ASN 303 ? E ASN 101 
584 1 Y 1 E ASN 304 ? E ASN 102 
585 1 Y 1 E ASN 305 ? E ASN 103 
586 1 Y 1 E TRP 306 ? E TRP 104 
587 1 Y 1 E GLY 307 ? E GLY 105 
588 1 Y 1 E PHE 308 ? E PHE 106 
589 1 Y 1 E ARG 309 ? E ARG 107 
590 1 Y 1 E PRO 310 ? E PRO 108 
591 1 Y 1 E LYS 311 ? E LYS 109 
592 1 Y 1 E ARG 312 ? E ARG 110 
593 1 Y 1 E LEU 313 ? E LEU 111 
594 1 Y 1 E ASN 314 ? E ASN 112 
595 1 Y 1 E PHE 315 ? E PHE 113 
596 1 Y 1 E LYS 316 ? E LYS 114 
597 1 Y 1 E LEU 317 ? E LEU 115 
598 1 Y 1 E PHE 318 ? E PHE 116 
599 1 Y 1 E ASN 319 ? E ASN 117 
600 1 Y 1 E ILE 320 ? E ILE 118 
601 1 Y 1 E GLN 321 ? E GLN 119 
602 1 Y 1 E VAL 322 ? E VAL 120 
603 1 Y 1 E LYS 323 ? E LYS 121 
604 1 Y 1 E GLU 324 ? E GLU 122 
605 1 Y 1 E VAL 325 ? E VAL 123 
606 1 Y 1 E THR 326 ? E THR 124 
607 1 Y 1 E ASP 327 ? E ASP 125 
608 1 Y 1 E ASN 328 ? E ASN 126 
609 1 Y 1 E ASN 329 ? E ASN 127 
610 1 Y 1 E GLY 330 ? E GLY 128 
611 1 Y 1 E VAL 331 ? E VAL 129 
612 1 Y 1 E LYS 332 ? E LYS 130 
613 1 Y 1 E THR 333 ? E THR 131 
614 1 Y 1 E ILE 334 ? E ILE 132 
615 1 Y 1 E ALA 335 ? E ALA 133 
616 1 Y 1 E ASN 336 ? E ASN 134 
617 1 Y 1 E ASN 337 ? E ASN 135 
618 1 Y 1 E LEU 338 ? E LEU 136 
619 1 Y 1 E THR 339 ? E THR 137 
620 1 Y 1 E SER 340 ? E SER 138 
621 1 Y 1 E THR 341 ? E THR 139 
622 1 Y 1 E VAL 342 ? E VAL 140 
623 1 Y 1 E GLN 343 ? E GLN 141 
624 1 Y 1 E VAL 344 ? E VAL 142 
625 1 Y 1 E PHE 345 ? E PHE 143 
626 1 Y 1 E THR 346 ? E THR 144 
627 1 Y 1 E ASP 347 ? E ASP 145 
628 1 Y 1 E SER 348 ? E SER 146 
629 1 Y 1 E ASP 349 ? E ASP 147 
630 1 Y 1 E TYR 350 ? E TYR 148 
631 1 Y 1 E GLN 351 ? E GLN 149 
632 1 Y 1 E LEU 352 ? E LEU 150 
633 1 Y 1 E PRO 353 ? E PRO 151 
634 1 Y 1 E TYR 354 ? E TYR 152 
635 1 Y 1 E VAL 355 ? E VAL 153 
636 1 Y 1 E LEU 356 ? E LEU 154 
637 1 Y 1 E GLY 357 ? E GLY 155 
638 1 Y 1 E SER 358 ? E SER 156 
639 1 Y 1 E ALA 359 ? E ALA 157 
640 1 Y 1 E HIS 360 ? E HIS 158 
641 1 Y 1 E GLU 361 ? E GLU 159 
642 1 Y 1 E GLY 362 ? E GLY 160 
643 1 Y 1 E CYS 363 ? E CYS 161 
644 1 Y 1 E LEU 364 ? E LEU 162 
645 1 Y 1 E PRO 365 ? E PRO 163 
646 1 Y 1 E PRO 366 ? E PRO 164 
647 1 Y 1 E PHE 367 ? E PHE 165 
648 1 Y 1 E PRO 368 ? E PRO 166 
649 1 Y 1 E ALA 369 ? E ALA 167 
650 1 Y 1 E ASP 370 ? E ASP 168 
651 1 Y 1 E VAL 371 ? E VAL 169 
652 1 Y 1 E PHE 372 ? E PHE 170 
653 1 Y 1 E MET 373 ? E MET 171 
654 1 Y 1 E ILE 374 ? E ILE 172 
655 1 Y 1 E PRO 375 ? E PRO 173 
656 1 Y 1 E GLN 376 ? E GLN 174 
657 1 Y 1 E TYR 377 ? E TYR 175 
658 1 Y 1 E GLY 378 ? E GLY 176 
659 1 Y 1 E TYR 379 ? E TYR 177 
660 1 Y 1 E LEU 380 ? E LEU 178 
661 1 Y 1 E THR 381 ? E THR 179 
662 1 Y 1 E LEU 382 ? E LEU 180 
663 1 Y 1 E ASN 383 ? E ASN 181 
664 1 Y 1 E ASP 384 ? E ASP 182 
665 1 Y 1 E GLY 385 ? E GLY 183 
666 1 Y 1 E SER 386 ? E SER 184 
667 1 Y 1 E GLN 387 ? E GLN 185 
668 1 Y 1 E ALA 388 ? E ALA 186 
669 1 Y 1 E VAL 389 ? E VAL 187 
670 1 Y 1 E GLY 390 ? E GLY 188 
671 1 Y 1 E ARG 391 ? E ARG 189 
672 1 Y 1 E SER 392 ? E SER 190 
673 1 Y 1 E SER 393 ? E SER 191 
674 1 Y 1 E PHE 394 ? E PHE 192 
675 1 Y 1 E TYR 395 ? E TYR 193 
676 1 Y 1 E CYS 396 ? E CYS 194 
677 1 Y 1 E LEU 397 ? E LEU 195 
678 1 Y 1 E GLU 398 ? E GLU 196 
679 1 Y 1 E TYR 399 ? E TYR 197 
680 1 Y 1 E PHE 400 ? E PHE 198 
681 1 Y 1 E PRO 401 ? E PRO 199 
682 1 Y 1 E SER 402 ? E SER 200 
683 1 Y 1 E GLN 403 ? E GLN 201 
684 1 Y 1 E MET 404 ? E MET 202 
685 1 Y 1 E LEU 405 ? E LEU 203 
686 1 Y 1 E ARG 406 ? E ARG 204 
687 1 Y 1 E THR 407 ? E THR 205 
688 1 Y 1 E GLY 408 ? E GLY 206 
689 1 Y 1 E ASN 409 ? E ASN 207 
690 1 Y 1 E ASN 410 ? E ASN 208 
691 1 Y 1 E PHE 411 ? E PHE 209 
692 1 Y 1 E GLN 412 ? E GLN 210 
693 1 Y 1 E PHE 413 ? E PHE 211 
694 1 Y 1 E SER 414 ? E SER 212 
695 1 Y 1 E TYR 415 ? E TYR 213 
696 1 Y 1 E GLU 416 ? E GLU 214 
697 1 Y 1 E GLY 544 ? E GLY 342 
698 1 Y 1 E LYS 545 ? E LYS 343 
699 1 Y 1 E GLN 546 ? E GLN 344 
700 1 Y 1 E GLY 547 ? E GLY 345 
701 1 Y 1 E THR 548 ? E THR 346 
702 1 Y 1 E GLY 549 ? E GLY 347 
703 1 Y 1 E ARG 550 ? E ARG 348 
704 1 Y 1 E ASP 551 ? E ASP 349 
705 1 Y 1 E ASN 552 ? E ASN 350 
706 1 Y 1 E VAL 553 ? E VAL 351 
707 1 Y 1 E ASP 554 ? E ASP 352 
708 1 Y 1 E ALA 555 ? E ALA 353 
709 1 Y 1 E ASP 556 ? E ASP 354 
710 1 Y 1 E LYS 557 ? E LYS 355 
711 1 Y 1 E PRO 645 ? E PRO 443 
712 1 Y 1 E GLN 646 ? E GLN 444 
713 1 Y 1 E ILE 647 ? E ILE 445 
714 1 Y 1 E LEU 648 ? E LEU 446 
715 1 Y 1 E ILE 649 ? E ILE 447 
716 1 Y 1 E LYS 650 ? E LYS 448 
717 1 Y 1 E ASN 651 ? E ASN 449 
718 1 Y 1 E THR 652 ? E THR 450 
719 1 Y 1 E PRO 653 ? E PRO 451 
720 1 Y 1 E VAL 654 ? E VAL 452 
721 1 Y 1 E PRO 655 ? E PRO 453 
722 1 Y 1 E ALA 656 ? E ALA 454 
723 1 Y 1 E ASP 657 ? E ASP 455 
724 1 Y 1 E PRO 658 ? E PRO 456 
725 1 Y 1 E PRO 659 ? E PRO 457 
726 1 Y 1 E THR 660 ? E THR 458 
727 1 Y 1 E ALA 661 ? E ALA 459 
728 1 Y 1 E PHE 662 ? E PHE 460 
729 1 Y 1 E ASN 663 ? E ASN 461 
730 1 Y 1 E LYS 664 ? E LYS 462 
731 1 Y 1 E ASP 665 ? E ASP 463 
732 1 Y 1 E LYS 666 ? E LYS 464 
733 1 Y 1 E LEU 667 ? E LEU 465 
734 1 Y 1 E ASN 668 ? E ASN 466 
735 1 Y 1 E SER 669 ? E SER 467 
736 1 Y 1 E PHE 670 ? E PHE 468 
737 1 Y 1 E ILE 671 ? E ILE 469 
738 1 Y 1 E THR 672 ? E THR 470 
739 1 Y 1 E GLN 673 ? E GLN 471 
740 1 Y 1 E TYR 674 ? E TYR 472 
741 1 Y 1 E SER 675 ? E SER 473 
742 1 Y 1 E THR 676 ? E THR 474 
743 1 Y 1 E GLY 677 ? E GLY 475 
744 1 Y 1 E GLN 678 ? E GLN 476 
745 1 Y 1 E VAL 679 ? E VAL 477 
746 1 Y 1 E SER 680 ? E SER 478 
747 1 Y 1 E VAL 681 ? E VAL 479 
748 1 Y 1 E GLU 682 ? E GLU 480 
749 1 Y 1 E ILE 683 ? E ILE 481 
750 1 Y 1 E GLU 684 ? E GLU 482 
751 1 Y 1 E TRP 685 ? E TRP 483 
752 1 Y 1 E GLU 686 ? E GLU 484 
753 1 Y 1 E LEU 687 ? E LEU 485 
754 1 Y 1 E GLN 688 ? E GLN 486 
755 1 Y 1 E LYS 689 ? E LYS 487 
756 1 Y 1 E GLU 690 ? E GLU 488 
757 1 Y 1 E ASN 691 ? E ASN 489 
758 1 Y 1 E SER 692 ? E SER 490 
759 1 Y 1 E LYS 693 ? E LYS 491 
760 1 Y 1 E ARG 694 ? E ARG 492 
761 1 Y 1 E TRP 695 ? E TRP 493 
762 1 Y 1 E ASN 696 ? E ASN 494 
763 1 Y 1 E PRO 697 ? E PRO 495 
764 1 Y 1 E GLU 698 ? E GLU 496 
765 1 Y 1 E ILE 699 ? E ILE 497 
766 1 Y 1 E GLN 700 ? E GLN 498 
767 1 Y 1 E TYR 701 ? E TYR 499 
768 1 Y 1 E THR 702 ? E THR 500 
769 1 Y 1 E SER 703 ? E SER 501 
770 1 Y 1 E ASN 704 ? E ASN 502 
771 1 Y 1 E TYR 705 ? E TYR 503 
772 1 Y 1 E TYR 706 ? E TYR 504 
773 1 Y 1 E LYS 707 ? E LYS 505 
774 1 Y 1 E SER 708 ? E SER 506 
775 1 Y 1 E ASN 709 ? E ASN 507 
776 1 Y 1 E ASN 710 ? E ASN 508 
777 1 Y 1 E VAL 711 ? E VAL 509 
778 1 Y 1 E GLU 712 ? E GLU 510 
779 1 Y 1 E PHE 713 ? E PHE 511 
780 1 Y 1 E ALA 714 ? E ALA 512 
781 1 Y 1 E VAL 715 ? E VAL 513 
782 1 Y 1 E ASN 716 ? E ASN 514 
783 1 Y 1 E THR 717 ? E THR 515 
784 1 Y 1 E GLU 718 ? E GLU 516 
785 1 Y 1 E GLY 719 ? E GLY 517 
786 1 Y 1 E VAL 720 ? E VAL 518 
787 1 Y 1 E TYR 721 ? E TYR 519 
788 1 Y 1 E SER 722 ? E SER 520 
789 1 Y 1 E GLU 723 ? E GLU 521 
790 1 Y 1 E PRO 724 ? E PRO 522 
791 1 Y 1 E ARG 725 ? E ARG 523 
792 1 Y 1 E PRO 726 ? E PRO 524 
793 1 Y 1 E ILE 727 ? E ILE 525 
794 1 Y 1 E GLY 728 ? E GLY 526 
795 1 Y 1 E THR 729 ? E THR 527 
796 1 Y 1 E ARG 730 ? E ARG 528 
797 1 Y 1 E TYR 731 ? E TYR 529 
798 1 Y 1 E LEU 732 ? E LEU 530 
799 1 Y 1 E THR 733 ? E THR 531 
800 1 Y 1 E ARG 734 ? E ARG 532 
801 1 Y 1 E ASN 735 ? E ASN 533 
802 1 Y 1 E LEU 736 ? E LEU 534 
803 1 Y 1 F MET 203 ? F MET 1   
804 1 Y 1 F ALA 204 ? F ALA 2   
805 1 Y 1 F SER 205 ? F SER 3   
806 1 Y 1 F GLY 206 ? F GLY 4   
807 1 Y 1 F GLY 207 ? F GLY 5   
808 1 Y 1 F GLY 208 ? F GLY 6   
809 1 Y 1 F ALA 209 ? F ALA 7   
810 1 Y 1 F PRO 210 ? F PRO 8   
811 1 Y 1 F VAL 211 ? F VAL 9   
812 1 Y 1 F ALA 212 ? F ALA 10  
813 1 Y 1 F ASP 213 ? F ASP 11  
814 1 Y 1 F ASN 214 ? F ASN 12  
815 1 Y 1 F ASN 215 ? F ASN 13  
816 1 Y 1 F GLU 216 ? F GLU 14  
817 1 Y 1 F GLY 217 ? F GLY 15  
818 1 Y 1 F ALA 218 ? F ALA 16  
819 1 Y 1 F PRO 645 ? F PRO 443 
820 1 Y 1 F GLN 646 ? F GLN 444 
821 1 Y 1 F ILE 647 ? F ILE 445 
822 1 Y 1 F LEU 648 ? F LEU 446 
823 1 Y 1 F ILE 649 ? F ILE 447 
824 1 Y 1 F LYS 650 ? F LYS 448 
825 1 Y 1 F ASN 651 ? F ASN 449 
826 1 Y 1 F THR 652 ? F THR 450 
827 1 Y 1 F PRO 653 ? F PRO 451 
828 1 Y 1 F VAL 654 ? F VAL 452 
829 1 Y 1 F PRO 655 ? F PRO 453 
830 1 Y 1 F ALA 656 ? F ALA 454 
831 1 Y 1 F ASP 657 ? F ASP 455 
832 1 Y 1 F PRO 658 ? F PRO 456 
833 1 Y 1 F PRO 659 ? F PRO 457 
834 1 Y 1 F THR 660 ? F THR 458 
835 1 Y 1 F ALA 661 ? F ALA 459 
836 1 Y 1 F PHE 662 ? F PHE 460 
837 1 Y 1 F ASN 663 ? F ASN 461 
838 1 Y 1 F LYS 664 ? F LYS 462 
839 1 Y 1 F ASP 665 ? F ASP 463 
840 1 Y 1 F LYS 666 ? F LYS 464 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
HOH O    O N N 158 
HOH H1   H N N 159 
HOH H2   H N N 160 
ILE N    N N N 161 
ILE CA   C N S 162 
ILE C    C N N 163 
ILE O    O N N 164 
ILE CB   C N S 165 
ILE CG1  C N N 166 
ILE CG2  C N N 167 
ILE CD1  C N N 168 
ILE OXT  O N N 169 
ILE H    H N N 170 
ILE H2   H N N 171 
ILE HA   H N N 172 
ILE HB   H N N 173 
ILE HG12 H N N 174 
ILE HG13 H N N 175 
ILE HG21 H N N 176 
ILE HG22 H N N 177 
ILE HG23 H N N 178 
ILE HD11 H N N 179 
ILE HD12 H N N 180 
ILE HD13 H N N 181 
ILE HXT  H N N 182 
LEU N    N N N 183 
LEU CA   C N S 184 
LEU C    C N N 185 
LEU O    O N N 186 
LEU CB   C N N 187 
LEU CG   C N N 188 
LEU CD1  C N N 189 
LEU CD2  C N N 190 
LEU OXT  O N N 191 
LEU H    H N N 192 
LEU H2   H N N 193 
LEU HA   H N N 194 
LEU HB2  H N N 195 
LEU HB3  H N N 196 
LEU HG   H N N 197 
LEU HD11 H N N 198 
LEU HD12 H N N 199 
LEU HD13 H N N 200 
LEU HD21 H N N 201 
LEU HD22 H N N 202 
LEU HD23 H N N 203 
LEU HXT  H N N 204 
LYS N    N N N 205 
LYS CA   C N S 206 
LYS C    C N N 207 
LYS O    O N N 208 
LYS CB   C N N 209 
LYS CG   C N N 210 
LYS CD   C N N 211 
LYS CE   C N N 212 
LYS NZ   N N N 213 
LYS OXT  O N N 214 
LYS H    H N N 215 
LYS H2   H N N 216 
LYS HA   H N N 217 
LYS HB2  H N N 218 
LYS HB3  H N N 219 
LYS HG2  H N N 220 
LYS HG3  H N N 221 
LYS HD2  H N N 222 
LYS HD3  H N N 223 
LYS HE2  H N N 224 
LYS HE3  H N N 225 
LYS HZ1  H N N 226 
LYS HZ2  H N N 227 
LYS HZ3  H N N 228 
LYS HXT  H N N 229 
MET N    N N N 230 
MET CA   C N S 231 
MET C    C N N 232 
MET O    O N N 233 
MET CB   C N N 234 
MET CG   C N N 235 
MET SD   S N N 236 
MET CE   C N N 237 
MET OXT  O N N 238 
MET H    H N N 239 
MET H2   H N N 240 
MET HA   H N N 241 
MET HB2  H N N 242 
MET HB3  H N N 243 
MET HG2  H N N 244 
MET HG3  H N N 245 
MET HE1  H N N 246 
MET HE2  H N N 247 
MET HE3  H N N 248 
MET HXT  H N N 249 
PHE N    N N N 250 
PHE CA   C N S 251 
PHE C    C N N 252 
PHE O    O N N 253 
PHE CB   C N N 254 
PHE CG   C Y N 255 
PHE CD1  C Y N 256 
PHE CD2  C Y N 257 
PHE CE1  C Y N 258 
PHE CE2  C Y N 259 
PHE CZ   C Y N 260 
PHE OXT  O N N 261 
PHE H    H N N 262 
PHE H2   H N N 263 
PHE HA   H N N 264 
PHE HB2  H N N 265 
PHE HB3  H N N 266 
PHE HD1  H N N 267 
PHE HD2  H N N 268 
PHE HE1  H N N 269 
PHE HE2  H N N 270 
PHE HZ   H N N 271 
PHE HXT  H N N 272 
PRO N    N N N 273 
PRO CA   C N S 274 
PRO C    C N N 275 
PRO O    O N N 276 
PRO CB   C N N 277 
PRO CG   C N N 278 
PRO CD   C N N 279 
PRO OXT  O N N 280 
PRO H    H N N 281 
PRO HA   H N N 282 
PRO HB2  H N N 283 
PRO HB3  H N N 284 
PRO HG2  H N N 285 
PRO HG3  H N N 286 
PRO HD2  H N N 287 
PRO HD3  H N N 288 
PRO HXT  H N N 289 
SER N    N N N 290 
SER CA   C N S 291 
SER C    C N N 292 
SER O    O N N 293 
SER CB   C N N 294 
SER OG   O N N 295 
SER OXT  O N N 296 
SER H    H N N 297 
SER H2   H N N 298 
SER HA   H N N 299 
SER HB2  H N N 300 
SER HB3  H N N 301 
SER HG   H N N 302 
SER HXT  H N N 303 
THR N    N N N 304 
THR CA   C N S 305 
THR C    C N N 306 
THR O    O N N 307 
THR CB   C N R 308 
THR OG1  O N N 309 
THR CG2  C N N 310 
THR OXT  O N N 311 
THR H    H N N 312 
THR H2   H N N 313 
THR HA   H N N 314 
THR HB   H N N 315 
THR HG1  H N N 316 
THR HG21 H N N 317 
THR HG22 H N N 318 
THR HG23 H N N 319 
THR HXT  H N N 320 
TRP N    N N N 321 
TRP CA   C N S 322 
TRP C    C N N 323 
TRP O    O N N 324 
TRP CB   C N N 325 
TRP CG   C Y N 326 
TRP CD1  C Y N 327 
TRP CD2  C Y N 328 
TRP NE1  N Y N 329 
TRP CE2  C Y N 330 
TRP CE3  C Y N 331 
TRP CZ2  C Y N 332 
TRP CZ3  C Y N 333 
TRP CH2  C Y N 334 
TRP OXT  O N N 335 
TRP H    H N N 336 
TRP H2   H N N 337 
TRP HA   H N N 338 
TRP HB2  H N N 339 
TRP HB3  H N N 340 
TRP HD1  H N N 341 
TRP HE1  H N N 342 
TRP HE3  H N N 343 
TRP HZ2  H N N 344 
TRP HZ3  H N N 345 
TRP HH2  H N N 346 
TRP HXT  H N N 347 
TYR N    N N N 348 
TYR CA   C N S 349 
TYR C    C N N 350 
TYR O    O N N 351 
TYR CB   C N N 352 
TYR CG   C Y N 353 
TYR CD1  C Y N 354 
TYR CD2  C Y N 355 
TYR CE1  C Y N 356 
TYR CE2  C Y N 357 
TYR CZ   C Y N 358 
TYR OH   O N N 359 
TYR OXT  O N N 360 
TYR H    H N N 361 
TYR H2   H N N 362 
TYR HA   H N N 363 
TYR HB2  H N N 364 
TYR HB3  H N N 365 
TYR HD1  H N N 366 
TYR HD2  H N N 367 
TYR HE1  H N N 368 
TYR HE2  H N N 369 
TYR HH   H N N 370 
TYR HXT  H N N 371 
VAL N    N N N 372 
VAL CA   C N S 373 
VAL C    C N N 374 
VAL O    O N N 375 
VAL CB   C N N 376 
VAL CG1  C N N 377 
VAL CG2  C N N 378 
VAL OXT  O N N 379 
VAL H    H N N 380 
VAL H2   H N N 381 
VAL HA   H N N 382 
VAL HB   H N N 383 
VAL HG11 H N N 384 
VAL HG12 H N N 385 
VAL HG13 H N N 386 
VAL HG21 H N N 387 
VAL HG22 H N N 388 
VAL HG23 H N N 389 
VAL HXT  H N N 390 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
PRO N   CA   sing N N 260 
PRO N   CD   sing N N 261 
PRO N   H    sing N N 262 
PRO CA  C    sing N N 263 
PRO CA  CB   sing N N 264 
PRO CA  HA   sing N N 265 
PRO C   O    doub N N 266 
PRO C   OXT  sing N N 267 
PRO CB  CG   sing N N 268 
PRO CB  HB2  sing N N 269 
PRO CB  HB3  sing N N 270 
PRO CG  CD   sing N N 271 
PRO CG  HG2  sing N N 272 
PRO CG  HG3  sing N N 273 
PRO CD  HD2  sing N N 274 
PRO CD  HD3  sing N N 275 
PRO OXT HXT  sing N N 276 
SER N   CA   sing N N 277 
SER N   H    sing N N 278 
SER N   H2   sing N N 279 
SER CA  C    sing N N 280 
SER CA  CB   sing N N 281 
SER CA  HA   sing N N 282 
SER C   O    doub N N 283 
SER C   OXT  sing N N 284 
SER CB  OG   sing N N 285 
SER CB  HB2  sing N N 286 
SER CB  HB3  sing N N 287 
SER OG  HG   sing N N 288 
SER OXT HXT  sing N N 289 
THR N   CA   sing N N 290 
THR N   H    sing N N 291 
THR N   H2   sing N N 292 
THR CA  C    sing N N 293 
THR CA  CB   sing N N 294 
THR CA  HA   sing N N 295 
THR C   O    doub N N 296 
THR C   OXT  sing N N 297 
THR CB  OG1  sing N N 298 
THR CB  CG2  sing N N 299 
THR CB  HB   sing N N 300 
THR OG1 HG1  sing N N 301 
THR CG2 HG21 sing N N 302 
THR CG2 HG22 sing N N 303 
THR CG2 HG23 sing N N 304 
THR OXT HXT  sing N N 305 
TRP N   CA   sing N N 306 
TRP N   H    sing N N 307 
TRP N   H2   sing N N 308 
TRP CA  C    sing N N 309 
TRP CA  CB   sing N N 310 
TRP CA  HA   sing N N 311 
TRP C   O    doub N N 312 
TRP C   OXT  sing N N 313 
TRP CB  CG   sing N N 314 
TRP CB  HB2  sing N N 315 
TRP CB  HB3  sing N N 316 
TRP CG  CD1  doub Y N 317 
TRP CG  CD2  sing Y N 318 
TRP CD1 NE1  sing Y N 319 
TRP CD1 HD1  sing N N 320 
TRP CD2 CE2  doub Y N 321 
TRP CD2 CE3  sing Y N 322 
TRP NE1 CE2  sing Y N 323 
TRP NE1 HE1  sing N N 324 
TRP CE2 CZ2  sing Y N 325 
TRP CE3 CZ3  doub Y N 326 
TRP CE3 HE3  sing N N 327 
TRP CZ2 CH2  doub Y N 328 
TRP CZ2 HZ2  sing N N 329 
TRP CZ3 CH2  sing Y N 330 
TRP CZ3 HZ3  sing N N 331 
TRP CH2 HH2  sing N N 332 
TRP OXT HXT  sing N N 333 
TYR N   CA   sing N N 334 
TYR N   H    sing N N 335 
TYR N   H2   sing N N 336 
TYR CA  C    sing N N 337 
TYR CA  CB   sing N N 338 
TYR CA  HA   sing N N 339 
TYR C   O    doub N N 340 
TYR C   OXT  sing N N 341 
TYR CB  CG   sing N N 342 
TYR CB  HB2  sing N N 343 
TYR CB  HB3  sing N N 344 
TYR CG  CD1  doub Y N 345 
TYR CG  CD2  sing Y N 346 
TYR CD1 CE1  sing Y N 347 
TYR CD1 HD1  sing N N 348 
TYR CD2 CE2  doub Y N 349 
TYR CD2 HD2  sing N N 350 
TYR CE1 CZ   doub Y N 351 
TYR CE1 HE1  sing N N 352 
TYR CE2 CZ   sing Y N 353 
TYR CE2 HE2  sing N N 354 
TYR CZ  OH   sing N N 355 
TYR OH  HH   sing N N 356 
TYR OXT HXT  sing N N 357 
VAL N   CA   sing N N 358 
VAL N   H    sing N N 359 
VAL N   H2   sing N N 360 
VAL CA  C    sing N N 361 
VAL CA  CB   sing N N 362 
VAL CA  HA   sing N N 363 
VAL C   O    doub N N 364 
VAL C   OXT  sing N N 365 
VAL CB  CG1  sing N N 366 
VAL CB  CG2  sing N N 367 
VAL CB  HB   sing N N 368 
VAL CG1 HG11 sing N N 369 
VAL CG1 HG12 sing N N 370 
VAL CG1 HG13 sing N N 371 
VAL CG2 HG21 sing N N 372 
VAL CG2 HG22 sing N N 373 
VAL CG2 HG23 sing N N 374 
VAL OXT HXT  sing N N 375 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-03-27 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9B7K 
_em_admin.last_update        2025-05-28 
_em_admin.map_release_date   2025-04-16 
_em_admin.title              'Fab2-1 in complex with the capsid of Adeno-associated virus type 9' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          272636 
_em_entity_assembly_naturalsource.organism             'Adeno-associated virus' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 HEK293 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'FEI FALCON IV (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ?      ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ?      ? 
MASKING                         ? 3  ? ? ? ?      ? 
'CTF CORRECTION'                ? 4  1 ? ? ?      ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ?      ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ?      ? 
'MODEL FITTING'                 ? 7  ? ? ? ?      ? 
'MODEL REFINEMENT'              ? 8  ? ? ? PHENIX ? 
OTHER                           ? 9  ? ? ? ?      ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ?      ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ?      ? 
CLASSIFICATION                  ? 12 1 ? ? ?      ? 
RECONSTRUCTION                  ? 13 1 ? ? ?      ? 
'VOLUME SELECTION'              ? 14 1 1 1 ?      ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ?      ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ?      ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ?      ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ?      ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ?      ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_em_virus_shell.diameter             ? 
_em_virus_shell.entity_assembly_id   1 
_em_virus_shell.id                   1 
_em_virus_shell.name                 ? 
_em_virus_shell.triangulation        1 
# 
_pdbx_audit_support.funding_organization   
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           GM082946 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9B7K 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . GLY A 1 18  ? -7.288  -42.400 73.509 1.00 75.75  ? 220 GLY A N   1 
ATOM   2     C CA  . GLY A 1 18  ? -6.609  -43.561 72.966 1.00 70.37  ? 220 GLY A CA  1 
ATOM   3     C C   . GLY A 1 18  ? -7.309  -44.151 71.759 1.00 67.02  ? 220 GLY A C   1 
ATOM   4     O O   . GLY A 1 18  ? -8.303  -43.607 71.281 1.00 67.75  ? 220 GLY A O   1 
ATOM   5     N N   . VAL A 1 19  ? -6.786  -45.272 71.263 1.00 70.56  ? 221 VAL A N   1 
ATOM   6     C CA  . VAL A 1 19  ? -7.378  -45.910 70.092 1.00 66.33  ? 221 VAL A CA  1 
ATOM   7     C C   . VAL A 1 19  ? -8.695  -46.586 70.455 1.00 65.20  ? 221 VAL A C   1 
ATOM   8     O O   . VAL A 1 19  ? -9.713  -46.393 69.780 1.00 66.06  ? 221 VAL A O   1 
ATOM   9     C CB  . VAL A 1 19  ? -6.386  -46.907 69.469 1.00 61.92  ? 221 VAL A CB  1 
ATOM   10    C CG1 . VAL A 1 19  ? -7.032  -47.640 68.310 1.00 61.17  ? 221 VAL A CG1 1 
ATOM   11    C CG2 . VAL A 1 19  ? -5.131  -46.188 69.015 1.00 61.95  ? 221 VAL A CG2 1 
ATOM   12    N N   . GLY A 1 20  ? -8.700  -47.379 71.520 1.00 65.18  ? 222 GLY A N   1 
ATOM   13    C CA  . GLY A 1 20  ? -9.844  -48.189 71.878 1.00 62.67  ? 222 GLY A CA  1 
ATOM   14    C C   . GLY A 1 20  ? -10.854 -47.548 72.802 1.00 62.40  ? 222 GLY A C   1 
ATOM   15    O O   . GLY A 1 20  ? -11.618 -48.272 73.449 1.00 62.63  ? 222 GLY A O   1 
ATOM   16    N N   . SER A 1 21  ? -10.892 -46.223 72.893 1.00 64.58  ? 223 SER A N   1 
ATOM   17    C CA  . SER A 1 21  ? -11.838 -45.532 73.757 1.00 63.14  ? 223 SER A CA  1 
ATOM   18    C C   . SER A 1 21  ? -12.727 -44.622 72.923 1.00 61.86  ? 223 SER A C   1 
ATOM   19    O O   . SER A 1 21  ? -12.288 -44.064 71.913 1.00 63.55  ? 223 SER A O   1 
ATOM   20    C CB  . SER A 1 21  ? -11.114 -44.723 74.834 1.00 64.05  ? 223 SER A CB  1 
ATOM   21    O OG  . SER A 1 21  ? -12.040 -44.054 75.671 1.00 69.09  ? 223 SER A OG  1 
ATOM   22    N N   . SER A 1 22  ? -13.978 -44.481 73.351 1.00 64.38  ? 224 SER A N   1 
ATOM   23    C CA  . SER A 1 22  ? -14.949 -43.684 72.618 1.00 62.66  ? 224 SER A CA  1 
ATOM   24    C C   . SER A 1 22  ? -14.800 -42.210 72.967 1.00 61.08  ? 224 SER A C   1 
ATOM   25    O O   . SER A 1 22  ? -14.717 -41.837 74.140 1.00 59.78  ? 224 SER A O   1 
ATOM   26    C CB  . SER A 1 22  ? -16.369 -44.159 72.928 1.00 55.21  ? 224 SER A CB  1 
ATOM   27    O OG  . SER A 1 22  ? -17.331 -43.377 72.243 1.00 59.36  ? 224 SER A OG  1 
ATOM   28    N N   . SER A 1 23  ? -14.763 -41.372 71.935 1.00 59.72  ? 225 SER A N   1 
ATOM   29    C CA  . SER A 1 23  ? -14.572 -39.939 72.100 1.00 59.06  ? 225 SER A CA  1 
ATOM   30    C C   . SER A 1 23  ? -15.872 -39.182 72.328 1.00 58.84  ? 225 SER A C   1 
ATOM   31    O O   . SER A 1 23  ? -15.831 -38.009 72.708 1.00 59.95  ? 225 SER A O   1 
ATOM   32    C CB  . SER A 1 23  ? -13.845 -39.371 70.880 1.00 54.95  ? 225 SER A CB  1 
ATOM   33    O OG  . SER A 1 23  ? -14.608 -39.566 69.706 1.00 56.86  ? 225 SER A OG  1 
ATOM   34    N N   . GLY A 1 24  ? -17.016 -39.820 72.118 1.00 57.50  ? 226 GLY A N   1 
ATOM   35    C CA  . GLY A 1 24  ? -18.294 -39.175 72.357 1.00 57.17  ? 226 GLY A CA  1 
ATOM   36    C C   . GLY A 1 24  ? -19.402 -40.201 72.327 1.00 57.24  ? 226 GLY A C   1 
ATOM   37    O O   . GLY A 1 24  ? -19.195 -41.361 71.962 1.00 57.87  ? 226 GLY A O   1 
ATOM   38    N N   . ASN A 1 25  ? -20.588 -39.758 72.725 1.00 56.56  ? 227 ASN A N   1 
ATOM   39    C CA  . ASN A 1 25  ? -21.753 -40.627 72.787 1.00 56.89  ? 227 ASN A CA  1 
ATOM   40    C C   . ASN A 1 25  ? -22.809 -40.162 71.793 1.00 58.54  ? 227 ASN A C   1 
ATOM   41    O O   . ASN A 1 25  ? -22.671 -39.131 71.133 1.00 60.99  ? 227 ASN A O   1 
ATOM   42    C CB  . ASN A 1 25  ? -22.335 -40.663 74.204 1.00 57.58  ? 227 ASN A CB  1 
ATOM   43    C CG  . ASN A 1 25  ? -21.428 -41.376 75.186 1.00 58.30  ? 227 ASN A CG  1 
ATOM   44    O OD1 . ASN A 1 25  ? -20.616 -42.218 74.802 1.00 58.98  ? 227 ASN A OD1 1 
ATOM   45    N ND2 . ASN A 1 25  ? -21.554 -41.035 76.462 1.00 58.73  ? 227 ASN A ND2 1 
ATOM   46    N N   . TRP A 1 26  ? -23.887 -40.936 71.712 1.00 56.09  ? 228 TRP A N   1 
ATOM   47    C CA  . TRP A 1 26  ? -24.970 -40.677 70.774 1.00 56.61  ? 228 TRP A CA  1 
ATOM   48    C C   . TRP A 1 26  ? -26.064 -39.909 71.500 1.00 58.10  ? 228 TRP A C   1 
ATOM   49    O O   . TRP A 1 26  ? -26.716 -40.454 72.397 1.00 58.52  ? 228 TRP A O   1 
ATOM   50    C CB  . TRP A 1 26  ? -25.530 -41.986 70.224 1.00 50.91  ? 228 TRP A CB  1 
ATOM   51    C CG  . TRP A 1 26  ? -26.599 -41.809 69.192 1.00 50.19  ? 228 TRP A CG  1 
ATOM   52    C CD1 . TRP A 1 26  ? -27.935 -41.698 69.416 1.00 49.59  ? 228 TRP A CD1 1 
ATOM   53    C CD2 . TRP A 1 26  ? -26.431 -41.817 67.770 1.00 49.65  ? 228 TRP A CD2 1 
ATOM   54    N NE1 . TRP A 1 26  ? -28.608 -41.583 68.227 1.00 49.97  ? 228 TRP A NE1 1 
ATOM   55    C CE2 . TRP A 1 26  ? -27.706 -41.660 67.200 1.00 50.12  ? 228 TRP A CE2 1 
ATOM   56    C CE3 . TRP A 1 26  ? -25.325 -41.931 66.925 1.00 49.45  ? 228 TRP A CE3 1 
ATOM   57    C CZ2 . TRP A 1 26  ? -27.906 -41.605 65.826 1.00 50.50  ? 228 TRP A CZ2 1 
ATOM   58    C CZ3 . TRP A 1 26  ? -25.524 -41.875 65.563 1.00 50.25  ? 228 TRP A CZ3 1 
ATOM   59    C CH2 . TRP A 1 26  ? -26.804 -41.713 65.026 1.00 50.46  ? 228 TRP A CH2 1 
ATOM   60    N N   . HIS A 1 27  ? -26.267 -38.650 71.126 1.00 54.55  ? 229 HIS A N   1 
ATOM   61    C CA  . HIS A 1 27  ? -27.305 -37.824 71.731 1.00 57.54  ? 229 HIS A CA  1 
ATOM   62    C C   . HIS A 1 27  ? -28.330 -37.458 70.667 1.00 59.16  ? 229 HIS A C   1 
ATOM   63    O O   . HIS A 1 27  ? -28.032 -36.685 69.751 1.00 60.26  ? 229 HIS A O   1 
ATOM   64    C CB  . HIS A 1 27  ? -26.710 -36.573 72.372 1.00 59.52  ? 229 HIS A CB  1 
ATOM   65    C CG  . HIS A 1 27  ? -25.845 -36.854 73.561 1.00 63.68  ? 229 HIS A CG  1 
ATOM   66    N ND1 . HIS A 1 27  ? -24.513 -37.189 73.453 1.00 64.52  ? 229 HIS A ND1 1 
ATOM   67    C CD2 . HIS A 1 27  ? -26.125 -36.852 74.886 1.00 65.36  ? 229 HIS A CD2 1 
ATOM   68    C CE1 . HIS A 1 27  ? -24.008 -37.377 74.659 1.00 66.02  ? 229 HIS A CE1 1 
ATOM   69    N NE2 . HIS A 1 27  ? -24.966 -37.180 75.546 1.00 67.48  ? 229 HIS A NE2 1 
ATOM   70    N N   . CYS A 1 28  ? -29.527 -38.028 70.780 1.00 57.48  ? 230 CYS A N   1 
ATOM   71    C CA  . CYS A 1 28  ? -30.672 -37.609 69.982 1.00 60.27  ? 230 CYS A CA  1 
ATOM   72    C C   . CYS A 1 28  ? -31.893 -37.566 70.884 1.00 61.69  ? 230 CYS A C   1 
ATOM   73    O O   . CYS A 1 28  ? -32.312 -38.603 71.406 1.00 63.08  ? 230 CYS A O   1 
ATOM   74    C CB  . CYS A 1 28  ? -30.911 -38.551 68.799 1.00 55.41  ? 230 CYS A CB  1 
ATOM   75    S SG  . CYS A 1 28  ? -29.608 -38.549 67.555 1.00 58.46  ? 230 CYS A SG  1 
ATOM   76    N N   . ASP A 1 29  ? -32.471 -36.374 71.042 1.00 59.81  ? 231 ASP A N   1 
ATOM   77    C CA  . ASP A 1 29  ? -33.677 -36.169 71.837 1.00 62.01  ? 231 ASP A CA  1 
ATOM   78    C C   . ASP A 1 29  ? -34.099 -34.707 71.800 1.00 59.91  ? 231 ASP A C   1 
ATOM   79    O O   . ASP A 1 29  ? -33.385 -33.861 71.254 1.00 60.26  ? 231 ASP A O   1 
ATOM   80    C CB  . ASP A 1 29  ? -33.474 -36.616 73.289 1.00 61.52  ? 231 ASP A CB  1 
ATOM   81    C CG  . ASP A 1 29  ? -32.323 -35.903 73.970 1.00 65.65  ? 231 ASP A CG  1 
ATOM   82    O OD1 . ASP A 1 29  ? -31.571 -35.180 73.284 1.00 67.94  ? 231 ASP A OD1 1 
ATOM   83    O OD2 . ASP A 1 29  ? -32.172 -36.064 75.198 1.00 67.92  ? 231 ASP A OD2 1 
ATOM   84    N N   . SER A 1 30  ? -35.256 -34.419 72.371 1.00 62.49  ? 232 SER A N   1 
ATOM   85    C CA  . SER A 1 30  ? -35.759 -33.064 72.416 1.00 61.65  ? 232 SER A CA  1 
ATOM   86    C C   . SER A 1 30  ? -36.469 -32.899 73.738 1.00 61.17  ? 232 SER A C   1 
ATOM   87    O O   . SER A 1 30  ? -37.535 -33.467 73.943 1.00 61.47  ? 232 SER A O   1 
ATOM   88    C CB  . SER A 1 30  ? -36.740 -32.817 71.275 1.00 57.73  ? 232 SER A CB  1 
ATOM   89    O OG  . SER A 1 30  ? -38.019 -33.328 71.599 1.00 57.78  ? 232 SER A OG  1 
ATOM   90    N N   . GLN A 1 31  ? -35.885 -32.123 74.638 1.00 61.13  ? 233 GLN A N   1 
ATOM   91    C CA  . GLN A 1 31  ? -36.504 -31.916 75.931 1.00 60.78  ? 233 GLN A CA  1 
ATOM   92    C C   . GLN A 1 31  ? -37.124 -30.537 75.995 1.00 59.05  ? 233 GLN A C   1 
ATOM   93    O O   . GLN A 1 31  ? -36.444 -29.537 75.802 1.00 58.82  ? 233 GLN A O   1 
ATOM   94    C CB  . GLN A 1 31  ? -35.476 -32.076 77.044 1.00 61.00  ? 233 GLN A CB  1 
ATOM   95    C CG  . GLN A 1 31  ? -34.224 -31.244 76.856 1.00 68.50  ? 233 GLN A CG  1 
ATOM   96    C CD  . GLN A 1 31  ? -33.278 -31.382 78.026 1.00 72.61  ? 233 GLN A CD  1 
ATOM   97    O OE1 . GLN A 1 31  ? -33.384 -32.324 78.811 1.00 74.37  ? 233 GLN A OE1 1 
ATOM   98    N NE2 . GLN A 1 31  ? -32.350 -30.442 78.156 1.00 73.88  ? 233 GLN A NE2 1 
ATOM   99    N N   . TRP A 1 32  ? -38.418 -30.490 76.289 1.00 62.18  ? 234 TRP A N   1 
ATOM   100   C CA  . TRP A 1 32  ? -39.122 -29.225 76.369 1.00 61.74  ? 234 TRP A CA  1 
ATOM   101   C C   . TRP A 1 32  ? -39.279 -28.804 77.814 1.00 63.30  ? 234 TRP A C   1 
ATOM   102   O O   . TRP A 1 32  ? -39.977 -29.454 78.586 1.00 63.49  ? 234 TRP A O   1 
ATOM   103   C CB  . TRP A 1 32  ? -40.510 -29.367 75.751 1.00 59.45  ? 234 TRP A CB  1 
ATOM   104   C CG  . TRP A 1 32  ? -40.487 -29.806 74.336 1.00 57.68  ? 234 TRP A CG  1 
ATOM   105   C CD1 . TRP A 1 32  ? -40.027 -30.991 73.857 1.00 57.09  ? 234 TRP A CD1 1 
ATOM   106   C CD2 . TRP A 1 32  ? -40.951 -29.067 73.204 1.00 56.25  ? 234 TRP A CD2 1 
ATOM   107   N NE1 . TRP A 1 32  ? -40.168 -31.036 72.495 1.00 54.74  ? 234 TRP A NE1 1 
ATOM   108   C CE2 . TRP A 1 32  ? -40.735 -29.865 72.070 1.00 55.18  ? 234 TRP A CE2 1 
ATOM   109   C CE3 . TRP A 1 32  ? -41.527 -27.806 73.041 1.00 54.32  ? 234 TRP A CE3 1 
ATOM   110   C CZ2 . TRP A 1 32  ? -41.074 -29.446 70.791 1.00 54.39  ? 234 TRP A CZ2 1 
ATOM   111   C CZ3 . TRP A 1 32  ? -41.862 -27.393 71.773 1.00 54.27  ? 234 TRP A CZ3 1 
ATOM   112   C CH2 . TRP A 1 32  ? -41.636 -28.209 70.664 1.00 54.67  ? 234 TRP A CH2 1 
ATOM   113   N N   . LEU A 1 33  ? -38.625 -27.711 78.175 1.00 63.66  ? 235 LEU A N   1 
ATOM   114   C CA  . LEU A 1 33  ? -38.713 -27.185 79.521 1.00 65.73  ? 235 LEU A CA  1 
ATOM   115   C C   . LEU A 1 33  ? -38.973 -25.696 79.451 1.00 66.73  ? 235 LEU A C   1 
ATOM   116   O O   . LEU A 1 33  ? -38.288 -24.985 78.726 1.00 67.77  ? 235 LEU A O   1 
ATOM   117   C CB  . LEU A 1 33  ? -37.419 -27.458 80.284 1.00 67.20  ? 235 LEU A CB  1 
ATOM   118   C CG  . LEU A 1 33  ? -36.145 -26.864 79.687 1.00 69.20  ? 235 LEU A CG  1 
ATOM   119   C CD1 . LEU A 1 33  ? -34.948 -27.170 80.574 1.00 69.59  ? 235 LEU A CD1 1 
ATOM   120   C CD2 . LEU A 1 33  ? -35.917 -27.388 78.278 1.00 69.06  ? 235 LEU A CD2 1 
ATOM   121   N N   . GLY A 1 34  ? -39.958 -25.217 80.200 1.00 65.97  ? 236 GLY A N   1 
ATOM   122   C CA  . GLY A 1 34  ? -40.247 -23.797 80.212 1.00 66.76  ? 236 GLY A CA  1 
ATOM   123   C C   . GLY A 1 34  ? -40.561 -23.233 78.844 1.00 67.48  ? 236 GLY A C   1 
ATOM   124   O O   . GLY A 1 34  ? -41.437 -23.722 78.135 1.00 68.49  ? 236 GLY A O   1 
ATOM   125   N N   . ASP A 1 35  ? -39.842 -22.174 78.490 1.00 65.31  ? 237 ASP A N   1 
ATOM   126   C CA  . ASP A 1 35  ? -40.015 -21.498 77.214 1.00 65.68  ? 237 ASP A CA  1 
ATOM   127   C C   . ASP A 1 35  ? -38.900 -21.813 76.216 1.00 62.97  ? 237 ASP A C   1 
ATOM   128   O O   . ASP A 1 35  ? -38.600 -21.006 75.351 1.00 61.95  ? 237 ASP A O   1 
ATOM   129   C CB  . ASP A 1 35  ? -40.083 -19.992 77.450 1.00 60.88  ? 237 ASP A CB  1 
ATOM   130   C CG  . ASP A 1 35  ? -39.127 -19.533 78.531 1.00 67.73  ? 237 ASP A CG  1 
ATOM   131   O OD1 . ASP A 1 35  ? -38.733 -20.371 79.367 1.00 71.02  ? 237 ASP A OD1 1 
ATOM   132   O OD2 . ASP A 1 35  ? -38.767 -18.341 78.550 1.00 69.90  ? 237 ASP A OD2 1 
ATOM   133   N N   . ARG A 1 36  ? -38.281 -22.980 76.355 1.00 62.86  ? 238 ARG A N   1 
ATOM   134   C CA  . ARG A 1 36  ? -37.209 -23.422 75.469 1.00 61.20  ? 238 ARG A CA  1 
ATOM   135   C C   . ARG A 1 36  ? -37.274 -24.888 75.078 1.00 57.40  ? 238 ARG A C   1 
ATOM   136   O O   . ARG A 1 36  ? -37.764 -25.726 75.825 1.00 56.84  ? 238 ARG A O   1 
ATOM   137   C CB  . ARG A 1 36  ? -35.839 -23.125 76.075 1.00 55.67  ? 238 ARG A CB  1 
ATOM   138   C CG  . ARG A 1 36  ? -35.848 -22.901 77.572 1.00 65.80  ? 238 ARG A CG  1 
ATOM   139   C CD  . ARG A 1 36  ? -35.960 -21.418 77.874 1.00 73.73  ? 238 ARG A CD  1 
ATOM   140   N NE  . ARG A 1 36  ? -34.897 -20.659 77.220 1.00 82.04  ? 238 ARG A NE  1 
ATOM   141   C CZ  . ARG A 1 36  ? -34.851 -19.333 77.159 1.00 85.16  ? 238 ARG A CZ  1 
ATOM   142   N NH1 . ARG A 1 36  ? -33.842 -18.732 76.546 1.00 86.98  ? 238 ARG A NH1 1 
ATOM   143   N NH2 . ARG A 1 36  ? -35.811 -18.607 77.711 1.00 84.94  ? 238 ARG A NH2 1 
ATOM   144   N N   . VAL A 1 37  ? -36.788 -25.177 73.877 1.00 57.62  ? 239 VAL A N   1 
ATOM   145   C CA  . VAL A 1 37  ? -36.745 -26.531 73.357 1.00 54.26  ? 239 VAL A CA  1 
ATOM   146   C C   . VAL A 1 37  ? -35.319 -26.841 72.937 1.00 52.96  ? 239 VAL A C   1 
ATOM   147   O O   . VAL A 1 37  ? -34.851 -26.359 71.915 1.00 51.82  ? 239 VAL A O   1 
ATOM   148   C CB  . VAL A 1 37  ? -37.644 -26.697 72.126 1.00 51.58  ? 239 VAL A CB  1 
ATOM   149   C CG1 . VAL A 1 37  ? -37.926 -28.169 71.882 1.00 49.06  ? 239 VAL A CG1 1 
ATOM   150   C CG2 . VAL A 1 37  ? -38.936 -25.922 72.300 1.00 54.28  ? 239 VAL A CG2 1 
ATOM   151   N N   . ILE A 1 38  ? -34.633 -27.637 73.741 1.00 56.31  ? 240 ILE A N   1 
ATOM   152   C CA  . ILE A 1 38  ? -33.261 -28.047 73.479 1.00 55.13  ? 240 ILE A CA  1 
ATOM   153   C C   . ILE A 1 38  ? -33.308 -29.286 72.603 1.00 55.86  ? 240 ILE A C   1 
ATOM   154   O O   . ILE A 1 38  ? -33.741 -30.355 73.050 1.00 56.66  ? 240 ILE A O   1 
ATOM   155   C CB  . ILE A 1 38  ? -32.483 -28.315 74.774 1.00 57.47  ? 240 ILE A CB  1 
ATOM   156   C CG1 . ILE A 1 38  ? -32.347 -27.028 75.591 1.00 57.24  ? 240 ILE A CG1 1 
ATOM   157   C CG2 . ILE A 1 38  ? -31.116 -28.888 74.452 1.00 55.27  ? 240 ILE A CG2 1 
ATOM   158   C CD1 . ILE A 1 38  ? -31.808 -27.252 76.982 1.00 59.31  ? 240 ILE A CD1 1 
ATOM   159   N N   . THR A 1 39  ? -32.872 -29.144 71.359 1.00 53.16  ? 241 THR A N   1 
ATOM   160   C CA  . THR A 1 39  ? -32.834 -30.247 70.416 1.00 53.63  ? 241 THR A CA  1 
ATOM   161   C C   . THR A 1 39  ? -31.396 -30.692 70.203 1.00 53.79  ? 241 THR A C   1 
ATOM   162   O O   . THR A 1 39  ? -30.472 -29.877 70.183 1.00 54.09  ? 241 THR A O   1 
ATOM   163   C CB  . THR A 1 39  ? -33.448 -29.851 69.074 1.00 51.72  ? 241 THR A CB  1 
ATOM   164   O OG1 . THR A 1 39  ? -32.726 -28.739 68.534 1.00 52.94  ? 241 THR A OG1 1 
ATOM   165   C CG2 . THR A 1 39  ? -34.907 -29.471 69.242 1.00 50.03  ? 241 THR A CG2 1 
ATOM   166   N N   . THR A 1 40  ? -31.214 -32.000 70.057 1.00 53.68  ? 242 THR A N   1 
ATOM   167   C CA  . THR A 1 40  ? -29.897 -32.562 69.806 1.00 55.39  ? 242 THR A CA  1 
ATOM   168   C C   . THR A 1 40  ? -30.022 -33.619 68.723 1.00 53.85  ? 242 THR A C   1 
ATOM   169   O O   . THR A 1 40  ? -30.836 -34.538 68.843 1.00 52.43  ? 242 THR A O   1 
ATOM   170   C CB  . THR A 1 40  ? -29.295 -33.182 71.069 1.00 54.05  ? 242 THR A CB  1 
ATOM   171   O OG1 . THR A 1 40  ? -29.282 -32.212 72.121 1.00 60.53  ? 242 THR A OG1 1 
ATOM   172   C CG2 . THR A 1 40  ? -27.872 -33.616 70.795 1.00 56.20  ? 242 THR A CG2 1 
ATOM   173   N N   . SER A 1 41  ? -29.225 -33.482 67.671 1.00 49.21  ? 243 SER A N   1 
ATOM   174   C CA  . SER A 1 41  ? -29.198 -34.441 66.579 1.00 49.33  ? 243 SER A CA  1 
ATOM   175   C C   . SER A 1 41  ? -27.824 -35.082 66.522 1.00 48.68  ? 243 SER A C   1 
ATOM   176   O O   . SER A 1 41  ? -26.827 -34.456 66.883 1.00 49.63  ? 243 SER A O   1 
ATOM   177   C CB  . SER A 1 41  ? -29.512 -33.779 65.240 1.00 47.86  ? 243 SER A CB  1 
ATOM   178   O OG  . SER A 1 41  ? -30.831 -33.268 65.224 1.00 53.55  ? 243 SER A OG  1 
ATOM   179   N N   . THR A 1 42  ? -27.778 -36.333 66.084 1.00 48.88  ? 244 THR A N   1 
ATOM   180   C CA  . THR A 1 42  ? -26.527 -37.036 65.856 1.00 47.39  ? 244 THR A CA  1 
ATOM   181   C C   . THR A 1 42  ? -26.669 -37.898 64.611 1.00 47.68  ? 244 THR A C   1 
ATOM   182   O O   . THR A 1 42  ? -27.681 -38.580 64.428 1.00 49.45  ? 244 THR A O   1 
ATOM   183   C CB  . THR A 1 42  ? -26.138 -37.900 67.058 1.00 49.47  ? 244 THR A CB  1 
ATOM   184   O OG1 . THR A 1 42  ? -26.071 -37.081 68.231 1.00 49.31  ? 244 THR A OG1 1 
ATOM   185   C CG2 . THR A 1 42  ? -24.782 -38.515 66.838 1.00 48.69  ? 244 THR A CG2 1 
ATOM   186   N N   . ARG A 1 43  ? -25.655 -37.853 63.751 1.00 45.02  ? 245 ARG A N   1 
ATOM   187   C CA  . ARG A 1 43  ? -25.658 -38.590 62.498 1.00 44.26  ? 245 ARG A CA  1 
ATOM   188   C C   . ARG A 1 43  ? -24.294 -39.226 62.289 1.00 43.87  ? 245 ARG A C   1 
ATOM   189   O O   . ARG A 1 43  ? -23.332 -38.940 63.005 1.00 44.07  ? 245 ARG A O   1 
ATOM   190   C CB  . ARG A 1 43  ? -25.992 -37.687 61.306 1.00 42.01  ? 245 ARG A CB  1 
ATOM   191   C CG  . ARG A 1 43  ? -27.326 -36.974 61.374 1.00 44.16  ? 245 ARG A CG  1 
ATOM   192   C CD  . ARG A 1 43  ? -28.483 -37.928 61.192 1.00 45.04  ? 245 ARG A CD  1 
ATOM   193   N NE  . ARG A 1 43  ? -29.752 -37.213 61.156 1.00 49.42  ? 245 ARG A NE  1 
ATOM   194   C CZ  . ARG A 1 43  ? -30.478 -36.932 62.231 1.00 50.08  ? 245 ARG A CZ  1 
ATOM   195   N NH1 . ARG A 1 43  ? -31.623 -36.277 62.109 1.00 50.98  ? 245 ARG A NH1 1 
ATOM   196   N NH2 . ARG A 1 43  ? -30.053 -37.297 63.432 1.00 51.01  ? 245 ARG A NH2 1 
ATOM   197   N N   . THR A 1 44  ? -24.221 -40.100 61.292 1.00 43.08  ? 246 THR A N   1 
ATOM   198   C CA  . THR A 1 44  ? -22.971 -40.705 60.856 1.00 43.65  ? 246 THR A CA  1 
ATOM   199   C C   . THR A 1 44  ? -22.648 -40.197 59.458 1.00 44.38  ? 246 THR A C   1 
ATOM   200   O O   . THR A 1 44  ? -23.536 -40.116 58.605 1.00 44.36  ? 246 THR A O   1 
ATOM   201   C CB  . THR A 1 44  ? -23.067 -42.232 60.864 1.00 45.40  ? 246 THR A CB  1 
ATOM   202   O OG1 . THR A 1 44  ? -23.315 -42.688 62.200 1.00 46.90  ? 246 THR A OG1 1 
ATOM   203   C CG2 . THR A 1 44  ? -21.777 -42.853 60.354 1.00 45.26  ? 246 THR A CG2 1 
ATOM   204   N N   . TRP A 1 45  ? -21.387 -39.846 59.230 1.00 41.88  ? 247 TRP A N   1 
ATOM   205   C CA  . TRP A 1 45  ? -20.962 -39.250 57.974 1.00 41.54  ? 247 TRP A CA  1 
ATOM   206   C C   . TRP A 1 45  ? -19.788 -40.011 57.374 1.00 42.78  ? 247 TRP A C   1 
ATOM   207   O O   . TRP A 1 45  ? -19.146 -40.834 58.029 1.00 42.50  ? 247 TRP A O   1 
ATOM   208   C CB  . TRP A 1 45  ? -20.572 -37.780 58.160 1.00 41.17  ? 247 TRP A CB  1 
ATOM   209   C CG  . TRP A 1 45  ? -19.562 -37.563 59.237 1.00 41.44  ? 247 TRP A CG  1 
ATOM   210   C CD1 . TRP A 1 45  ? -19.812 -37.263 60.538 1.00 41.17  ? 247 TRP A CD1 1 
ATOM   211   C CD2 . TRP A 1 45  ? -18.141 -37.665 59.114 1.00 41.57  ? 247 TRP A CD2 1 
ATOM   212   N NE1 . TRP A 1 45  ? -18.636 -37.147 61.232 1.00 39.85  ? 247 TRP A NE1 1 
ATOM   213   C CE2 . TRP A 1 45  ? -17.594 -37.393 60.379 1.00 40.21  ? 247 TRP A CE2 1 
ATOM   214   C CE3 . TRP A 1 45  ? -17.277 -37.952 58.055 1.00 42.44  ? 247 TRP A CE3 1 
ATOM   215   C CZ2 . TRP A 1 45  ? -16.226 -37.402 60.614 1.00 40.11  ? 247 TRP A CZ2 1 
ATOM   216   C CZ3 . TRP A 1 45  ? -15.925 -37.956 58.290 1.00 41.91  ? 247 TRP A CZ3 1 
ATOM   217   C CH2 . TRP A 1 45  ? -15.410 -37.684 59.557 1.00 40.79  ? 247 TRP A CH2 1 
ATOM   218   N N   . ALA A 1 46  ? -19.521 -39.721 56.103 1.00 39.39  ? 248 ALA A N   1 
ATOM   219   C CA  . ALA A 1 46  ? -18.377 -40.262 55.385 1.00 39.97  ? 248 ALA A CA  1 
ATOM   220   C C   . ALA A 1 46  ? -17.754 -39.149 54.557 1.00 40.02  ? 248 ALA A C   1 
ATOM   221   O O   . ALA A 1 46  ? -18.451 -38.481 53.787 1.00 40.57  ? 248 ALA A O   1 
ATOM   222   C CB  . ALA A 1 46  ? -18.788 -41.431 54.486 1.00 44.25  ? 248 ALA A CB  1 
ATOM   223   N N   . LEU A 1 47  ? -16.447 -38.953 54.711 1.00 36.78  ? 249 LEU A N   1 
ATOM   224   C CA  . LEU A 1 47  ? -15.737 -37.869 54.042 1.00 36.20  ? 249 LEU A CA  1 
ATOM   225   C C   . LEU A 1 47  ? -14.730 -38.431 53.047 1.00 37.04  ? 249 LEU A C   1 
ATOM   226   O O   . LEU A 1 47  ? -13.728 -39.036 53.462 1.00 37.50  ? 249 LEU A O   1 
ATOM   227   C CB  . LEU A 1 47  ? -15.034 -36.976 55.063 1.00 34.63  ? 249 LEU A CB  1 
ATOM   228   C CG  . LEU A 1 47  ? -14.212 -35.826 54.489 1.00 33.92  ? 249 LEU A CG  1 
ATOM   229   C CD1 . LEU A 1 47  ? -15.096 -34.893 53.688 1.00 33.92  ? 249 LEU A CD1 1 
ATOM   230   C CD2 . LEU A 1 47  ? -13.531 -35.075 55.609 1.00 34.83  ? 249 LEU A CD2 1 
ATOM   231   N N   . PRO A 1 48  ? -14.943 -38.266 51.750 1.00 30.81  ? 250 PRO A N   1 
ATOM   232   C CA  . PRO A 1 48  ? -13.979 -38.739 50.754 1.00 31.63  ? 250 PRO A CA  1 
ATOM   233   C C   . PRO A 1 48  ? -12.877 -37.712 50.516 1.00 32.81  ? 250 PRO A C   1 
ATOM   234   O O   . PRO A 1 48  ? -12.740 -36.723 51.232 1.00 33.37  ? 250 PRO A O   1 
ATOM   235   C CB  . PRO A 1 48  ? -14.841 -38.918 49.507 1.00 31.29  ? 250 PRO A CB  1 
ATOM   236   C CG  . PRO A 1 48  ? -15.889 -37.883 49.655 1.00 30.27  ? 250 PRO A CG  1 
ATOM   237   C CD  . PRO A 1 48  ? -16.180 -37.772 51.125 1.00 30.22  ? 250 PRO A CD  1 
ATOM   238   N N   . THR A 1 49  ? -12.080 -37.977 49.487 1.00 30.46  ? 251 THR A N   1 
ATOM   239   C CA  . THR A 1 49  ? -11.067 -37.052 49.000 1.00 30.79  ? 251 THR A CA  1 
ATOM   240   C C   . THR A 1 49  ? -11.559 -36.390 47.720 1.00 30.91  ? 251 THR A C   1 
ATOM   241   O O   . THR A 1 49  ? -11.871 -37.078 46.742 1.00 30.57  ? 251 THR A O   1 
ATOM   242   C CB  . THR A 1 49  ? -9.748  -37.779 48.743 1.00 29.42  ? 251 THR A CB  1 
ATOM   243   O OG1 . THR A 1 49  ? -9.219  -38.262 49.984 1.00 30.60  ? 251 THR A OG1 1 
ATOM   244   C CG2 . THR A 1 49  ? -8.746  -36.855 48.077 1.00 27.83  ? 251 THR A CG2 1 
ATOM   245   N N   . TYR A 1 50  ? -11.618 -35.062 47.724 1.00 25.23  ? 252 TYR A N   1 
ATOM   246   C CA  . TYR A 1 50  ? -12.128 -34.294 46.597 1.00 26.22  ? 252 TYR A CA  1 
ATOM   247   C C   . TYR A 1 50  ? -10.977 -33.712 45.791 1.00 27.54  ? 252 TYR A C   1 
ATOM   248   O O   . TYR A 1 50  ? -10.015 -33.191 46.363 1.00 28.94  ? 252 TYR A O   1 
ATOM   249   C CB  . TYR A 1 50  ? -13.047 -33.171 47.068 1.00 26.29  ? 252 TYR A CB  1 
ATOM   250   C CG  . TYR A 1 50  ? -14.311 -33.639 47.739 1.00 24.81  ? 252 TYR A CG  1 
ATOM   251   C CD1 . TYR A 1 50  ? -15.402 -34.045 46.989 1.00 24.62  ? 252 TYR A CD1 1 
ATOM   252   C CD2 . TYR A 1 50  ? -14.429 -33.636 49.117 1.00 24.21  ? 252 TYR A CD2 1 
ATOM   253   C CE1 . TYR A 1 50  ? -16.563 -34.459 47.591 1.00 23.60  ? 252 TYR A CE1 1 
ATOM   254   C CE2 . TYR A 1 50  ? -15.590 -34.051 49.728 1.00 24.17  ? 252 TYR A CE2 1 
ATOM   255   C CZ  . TYR A 1 50  ? -16.652 -34.457 48.959 1.00 24.36  ? 252 TYR A CZ  1 
ATOM   256   O OH  . TYR A 1 50  ? -17.811 -34.874 49.557 1.00 26.38  ? 252 TYR A OH  1 
ATOM   257   N N   . ASN A 1 51  ? -11.078 -33.815 44.465 1.00 24.29  ? 253 ASN A N   1 
ATOM   258   C CA  . ASN A 1 51  ? -10.113 -33.233 43.527 1.00 26.14  ? 253 ASN A CA  1 
ATOM   259   C C   . ASN A 1 51  ? -8.696  -33.747 43.745 1.00 27.45  ? 253 ASN A C   1 
ATOM   260   O O   . ASN A 1 51  ? -7.734  -33.099 43.334 1.00 28.32  ? 253 ASN A O   1 
ATOM   261   C CB  . ASN A 1 51  ? -10.106 -31.703 43.593 1.00 21.12  ? 253 ASN A CB  1 
ATOM   262   C CG  . ASN A 1 51  ? -11.316 -31.077 42.954 1.00 21.63  ? 253 ASN A CG  1 
ATOM   263   O OD1 . ASN A 1 51  ? -11.980 -31.684 42.120 1.00 23.20  ? 253 ASN A OD1 1 
ATOM   264   N ND2 . ASN A 1 51  ? -11.593 -29.836 43.322 1.00 19.93  ? 253 ASN A ND2 1 
ATOM   265   N N   . ASN A 1 52  ? -8.548  -34.912 44.370 1.00 26.27  ? 254 ASN A N   1 
ATOM   266   C CA  . ASN A 1 52  ? -7.234  -35.482 44.668 1.00 28.54  ? 254 ASN A CA  1 
ATOM   267   C C   . ASN A 1 52  ? -6.389  -34.518 45.500 1.00 28.03  ? 254 ASN A C   1 
ATOM   268   O O   . ASN A 1 52  ? -5.228  -34.246 45.191 1.00 27.64  ? 254 ASN A O   1 
ATOM   269   C CB  . ASN A 1 52  ? -6.504  -35.874 43.383 1.00 24.45  ? 254 ASN A CB  1 
ATOM   270   C CG  . ASN A 1 52  ? -7.176  -37.013 42.659 1.00 30.02  ? 254 ASN A CG  1 
ATOM   271   O OD1 . ASN A 1 52  ? -7.043  -38.173 43.045 1.00 33.38  ? 254 ASN A OD1 1 
ATOM   272   N ND2 . ASN A 1 52  ? -7.907  -36.689 41.600 1.00 32.62  ? 254 ASN A ND2 1 
ATOM   273   N N   . HIS A 1 53  ? -6.992  -33.994 46.566 1.00 26.98  ? 255 HIS A N   1 
ATOM   274   C CA  . HIS A 1 53  ? -6.317  -33.100 47.509 1.00 27.04  ? 255 HIS A CA  1 
ATOM   275   C C   . HIS A 1 53  ? -5.790  -31.848 46.814 1.00 25.82  ? 255 HIS A C   1 
ATOM   276   O O   . HIS A 1 53  ? -4.690  -31.370 47.096 1.00 27.22  ? 255 HIS A O   1 
ATOM   277   C CB  . HIS A 1 53  ? -5.172  -33.815 48.227 1.00 26.54  ? 255 HIS A CB  1 
ATOM   278   C CG  . HIS A 1 53  ? -5.586  -35.036 48.984 1.00 29.76  ? 255 HIS A CG  1 
ATOM   279   N ND1 . HIS A 1 53  ? -6.355  -34.980 50.126 1.00 32.57  ? 255 HIS A ND1 1 
ATOM   280   C CD2 . HIS A 1 53  ? -5.311  -36.344 48.779 1.00 29.29  ? 255 HIS A CD2 1 
ATOM   281   C CE1 . HIS A 1 53  ? -6.546  -36.203 50.584 1.00 32.89  ? 255 HIS A CE1 1 
ATOM   282   N NE2 . HIS A 1 53  ? -5.923  -37.050 49.785 1.00 31.48  ? 255 HIS A NE2 1 
ATOM   283   N N   . LEU A 1 54  ? -6.583  -31.300 45.901 1.00 22.59  ? 256 LEU A N   1 
ATOM   284   C CA  . LEU A 1 54  ? -6.077  -30.286 44.993 1.00 19.19  ? 256 LEU A CA  1 
ATOM   285   C C   . LEU A 1 54  ? -7.140  -29.228 44.724 1.00 19.15  ? 256 LEU A C   1 
ATOM   286   O O   . LEU A 1 54  ? -8.342  -29.491 44.783 1.00 20.14  ? 256 LEU A O   1 
ATOM   287   C CB  . LEU A 1 54  ? -5.602  -30.950 43.695 1.00 22.99  ? 256 LEU A CB  1 
ATOM   288   C CG  . LEU A 1 54  ? -4.957  -30.189 42.547 1.00 20.45  ? 256 LEU A CG  1 
ATOM   289   C CD1 . LEU A 1 54  ? -3.664  -29.557 43.013 1.00 18.78  ? 256 LEU A CD1 1 
ATOM   290   C CD2 . LEU A 1 54  ? -4.701  -31.159 41.412 1.00 19.32  ? 256 LEU A CD2 1 
ATOM   291   N N   . TYR A 1 55  ? -6.676  -28.009 44.462 1.00 17.58  ? 257 TYR A N   1 
ATOM   292   C CA  . TYR A 1 55  ? -7.525  -26.886 44.085 1.00 17.01  ? 257 TYR A CA  1 
ATOM   293   C C   . TYR A 1 55  ? -7.584  -26.792 42.571 1.00 17.11  ? 257 TYR A C   1 
ATOM   294   O O   . TYR A 1 55  ? -6.574  -27.003 41.897 1.00 18.37  ? 257 TYR A O   1 
ATOM   295   C CB  . TYR A 1 55  ? -6.992  -25.572 44.653 1.00 16.06  ? 257 TYR A CB  1 
ATOM   296   C CG  . TYR A 1 55  ? -7.113  -25.425 46.145 1.00 17.00  ? 257 TYR A CG  1 
ATOM   297   C CD1 . TYR A 1 55  ? -8.188  -24.762 46.709 1.00 17.02  ? 257 TYR A CD1 1 
ATOM   298   C CD2 . TYR A 1 55  ? -6.165  -25.967 46.991 1.00 16.99  ? 257 TYR A CD2 1 
ATOM   299   C CE1 . TYR A 1 55  ? -8.300  -24.623 48.073 1.00 18.12  ? 257 TYR A CE1 1 
ATOM   300   C CE2 . TYR A 1 55  ? -6.273  -25.840 48.355 1.00 18.68  ? 257 TYR A CE2 1 
ATOM   301   C CZ  . TYR A 1 55  ? -7.341  -25.166 48.890 1.00 19.25  ? 257 TYR A CZ  1 
ATOM   302   O OH  . TYR A 1 55  ? -7.451  -25.040 50.251 1.00 21.49  ? 257 TYR A OH  1 
ATOM   303   N N   . LYS A 1 56  ? -8.756  -26.468 42.039 1.00 16.02  ? 258 LYS A N   1 
ATOM   304   C CA  . LYS A 1 56  ? -8.929  -26.337 40.600 1.00 15.88  ? 258 LYS A CA  1 
ATOM   305   C C   . LYS A 1 56  ? -9.813  -25.144 40.287 1.00 15.22  ? 258 LYS A C   1 
ATOM   306   O O   . LYS A 1 56  ? -10.919 -25.028 40.821 1.00 16.00  ? 258 LYS A O   1 
ATOM   307   C CB  . LYS A 1 56  ? -9.533  -27.607 39.997 1.00 18.00  ? 258 LYS A CB  1 
ATOM   308   C CG  . LYS A 1 56  ? -8.631  -28.825 40.056 1.00 21.45  ? 258 LYS A CG  1 
ATOM   309   C CD  . LYS A 1 56  ? -9.325  -30.043 39.485 1.00 22.44  ? 258 LYS A CD  1 
ATOM   310   C CE  . LYS A 1 56  ? -8.434  -31.267 39.543 1.00 24.50  ? 258 LYS A CE  1 
ATOM   311   N NZ  . LYS A 1 56  ? -7.224  -31.098 38.697 1.00 27.33  ? 258 LYS A NZ  1 
ATOM   312   N N   . GLN A 1 57  ? -9.317  -24.259 39.430 1.00 16.19  ? 259 GLN A N   1 
ATOM   313   C CA  . GLN A 1 57  ? -10.158 -23.246 38.813 1.00 15.95  ? 259 GLN A CA  1 
ATOM   314   C C   . GLN A 1 57  ? -11.315 -23.903 38.076 1.00 16.54  ? 259 GLN A C   1 
ATOM   315   O O   . GLN A 1 57  ? -11.117 -24.840 37.297 1.00 16.69  ? 259 GLN A O   1 
ATOM   316   C CB  . GLN A 1 57  ? -9.337  -22.407 37.841 1.00 13.95  ? 259 GLN A CB  1 
ATOM   317   C CG  . GLN A 1 57  ? -10.156 -21.451 37.006 1.00 14.70  ? 259 GLN A CG  1 
ATOM   318   C CD  . GLN A 1 57  ? -9.311  -20.652 36.049 1.00 17.03  ? 259 GLN A CD  1 
ATOM   319   O OE1 . GLN A 1 57  ? -8.093  -20.603 36.173 1.00 20.65  ? 259 GLN A OE1 1 
ATOM   320   N NE2 . GLN A 1 57  ? -9.948  -20.081 35.042 1.00 15.40  ? 259 GLN A NE2 1 
ATOM   321   N N   . ILE A 1 58  ? -12.525 -23.415 38.326 1.00 17.25  ? 260 ILE A N   1 
ATOM   322   C CA  . ILE A 1 58  ? -13.706 -23.860 37.600 1.00 18.04  ? 260 ILE A CA  1 
ATOM   323   C C   . ILE A 1 58  ? -14.413 -22.638 37.033 1.00 20.96  ? 260 ILE A C   1 
ATOM   324   O O   . ILE A 1 58  ? -14.429 -21.561 37.637 1.00 21.73  ? 260 ILE A O   1 
ATOM   325   C CB  . ILE A 1 58  ? -14.660 -24.701 38.480 1.00 17.16  ? 260 ILE A CB  1 
ATOM   326   C CG1 . ILE A 1 58  ? -15.099 -23.918 39.712 1.00 16.12  ? 260 ILE A CG1 1 
ATOM   327   C CG2 . ILE A 1 58  ? -14.002 -25.998 38.894 1.00 13.97  ? 260 ILE A CG2 1 
ATOM   328   C CD1 . ILE A 1 58  ? -16.152 -24.624 40.520 1.00 15.53  ? 260 ILE A CD1 1 
ATOM   329   N N   . SER A 1 59  ? -14.975 -22.810 35.843 1.00 23.87  ? 261 SER A N   1 
ATOM   330   C CA  . SER A 1 59  ? -15.680 -21.747 35.143 1.00 26.26  ? 261 SER A CA  1 
ATOM   331   C C   . SER A 1 59  ? -16.654 -22.404 34.180 1.00 28.88  ? 261 SER A C   1 
ATOM   332   O O   . SER A 1 59  ? -16.583 -23.609 33.932 1.00 28.76  ? 261 SER A O   1 
ATOM   333   C CB  . SER A 1 59  ? -14.716 -20.816 34.409 1.00 25.16  ? 261 SER A CB  1 
ATOM   334   O OG  . SER A 1 59  ? -14.020 -21.505 33.388 1.00 24.27  ? 261 SER A OG  1 
ATOM   335   N N   . ASN A 1 60  ? -17.586 -21.604 33.656 1.00 29.62  ? 262 ASN A N   1 
ATOM   336   C CA  . ASN A 1 60  ? -18.577 -22.153 32.737 1.00 33.02  ? 262 ASN A CA  1 
ATOM   337   C C   . ASN A 1 60  ? -17.902 -22.815 31.545 1.00 35.90  ? 262 ASN A C   1 
ATOM   338   O O   . ASN A 1 60  ? -18.404 -23.807 31.008 1.00 36.23  ? 262 ASN A O   1 
ATOM   339   C CB  . ASN A 1 60  ? -19.550 -21.060 32.281 1.00 32.48  ? 262 ASN A CB  1 
ATOM   340   C CG  . ASN A 1 60  ? -18.915 -20.030 31.351 1.00 31.97  ? 262 ASN A CG  1 
ATOM   341   O OD1 . ASN A 1 60  ? -18.123 -20.355 30.471 1.00 31.51  ? 262 ASN A OD1 1 
ATOM   342   N ND2 . ASN A 1 60  ? -19.271 -18.777 31.548 1.00 32.02  ? 262 ASN A ND2 1 
ATOM   343   N N   . SER A 1 61  ? -16.757 -22.272 31.122 1.00 33.65  ? 263 SER A N   1 
ATOM   344   C CA  . SER A 1 61  ? -16.007 -22.853 30.015 1.00 37.28  ? 263 SER A CA  1 
ATOM   345   C C   . SER A 1 61  ? -15.574 -24.278 30.327 1.00 39.43  ? 263 SER A C   1 
ATOM   346   O O   . SER A 1 61  ? -15.544 -25.134 29.436 1.00 40.04  ? 263 SER A O   1 
ATOM   347   C CB  . SER A 1 61  ? -14.794 -21.979 29.698 1.00 38.85  ? 263 SER A CB  1 
ATOM   348   O OG  . SER A 1 61  ? -14.013 -22.537 28.657 1.00 40.23  ? 263 SER A OG  1 
ATOM   349   N N   . THR A 1 62  ? -15.229 -24.552 31.587 1.00 37.04  ? 264 THR A N   1 
ATOM   350   C CA  . THR A 1 62  ? -14.878 -25.914 31.971 1.00 38.66  ? 264 THR A CA  1 
ATOM   351   C C   . THR A 1 62  ? -16.088 -26.835 31.877 1.00 40.44  ? 264 THR A C   1 
ATOM   352   O O   . THR A 1 62  ? -15.956 -28.014 31.530 1.00 40.07  ? 264 THR A O   1 
ATOM   353   C CB  . THR A 1 62  ? -14.294 -25.933 33.385 1.00 35.27  ? 264 THR A CB  1 
ATOM   354   O OG1 . THR A 1 62  ? -15.257 -25.415 34.309 1.00 33.99  ? 264 THR A OG1 1 
ATOM   355   C CG2 . THR A 1 62  ? -13.036 -25.085 33.453 1.00 34.74  ? 264 THR A CG2 1 
ATOM   356   N N   . SER A 1 63  ? -17.278 -26.313 32.188 1.00 41.26  ? 265 SER A N   1 
ATOM   357   C CA  . SER A 1 63  ? -18.503 -27.092 32.050 1.00 43.05  ? 265 SER A CA  1 
ATOM   358   C C   . SER A 1 63  ? -19.232 -26.805 30.741 1.00 44.60  ? 265 SER A C   1 
ATOM   359   O O   . SER A 1 63  ? -20.269 -27.420 30.470 1.00 45.00  ? 265 SER A O   1 
ATOM   360   C CB  . SER A 1 63  ? -19.433 -26.820 33.232 1.00 40.75  ? 265 SER A CB  1 
ATOM   361   O OG  . SER A 1 63  ? -18.848 -27.252 34.447 1.00 42.37  ? 265 SER A OG  1 
ATOM   362   N N   . GLY A 1 64  ? -18.725 -25.886 29.933 1.00 45.68  ? 266 GLY A N   1 
ATOM   363   C CA  . GLY A 1 64  ? -19.322 -25.553 28.655 1.00 46.95  ? 266 GLY A CA  1 
ATOM   364   C C   . GLY A 1 64  ? -20.656 -24.839 28.799 1.00 47.82  ? 266 GLY A C   1 
ATOM   365   O O   . GLY A 1 64  ? -21.075 -24.450 29.894 1.00 48.48  ? 266 GLY A O   1 
ATOM   366   N N   . GLY A 1 65  ? -21.334 -24.661 27.667 1.00 57.34  ? 267 GLY A N   1 
ATOM   367   C CA  . GLY A 1 65  ? -22.677 -24.110 27.626 1.00 56.20  ? 267 GLY A CA  1 
ATOM   368   C C   . GLY A 1 65  ? -22.770 -22.659 27.197 1.00 55.18  ? 267 GLY A C   1 
ATOM   369   O O   . GLY A 1 65  ? -23.801 -22.242 26.661 1.00 54.67  ? 267 GLY A O   1 
ATOM   370   N N   . SER A 1 66  ? -21.697 -21.894 27.412 1.00 57.12  ? 268 SER A N   1 
ATOM   371   C CA  . SER A 1 66  ? -21.531 -20.545 26.854 1.00 55.38  ? 268 SER A CA  1 
ATOM   372   C C   . SER A 1 66  ? -22.792 -19.692 26.985 1.00 53.74  ? 268 SER A C   1 
ATOM   373   O O   . SER A 1 66  ? -23.161 -18.956 26.067 1.00 53.12  ? 268 SER A O   1 
ATOM   374   C CB  . SER A 1 66  ? -21.078 -20.612 25.393 1.00 61.16  ? 268 SER A CB  1 
ATOM   375   O OG  . SER A 1 66  ? -22.058 -21.228 24.576 1.00 60.75  ? 268 SER A OG  1 
ATOM   376   N N   . SER A 1 67  ? -23.466 -19.788 28.128 1.00 48.10  ? 269 SER A N   1 
ATOM   377   C CA  . SER A 1 67  ? -24.671 -19.012 28.394 1.00 45.29  ? 269 SER A CA  1 
ATOM   378   C C   . SER A 1 67  ? -24.316 -17.840 29.296 1.00 43.59  ? 269 SER A C   1 
ATOM   379   O O   . SER A 1 67  ? -23.720 -18.032 30.360 1.00 42.63  ? 269 SER A O   1 
ATOM   380   C CB  . SER A 1 67  ? -25.758 -19.877 29.037 1.00 49.35  ? 269 SER A CB  1 
ATOM   381   O OG  . SER A 1 67  ? -26.917 -19.113 29.314 1.00 47.95  ? 269 SER A OG  1 
ATOM   382   N N   . ASN A 1 68  ? -24.692 -16.631 28.872 1.00 39.65  ? 270 ASN A N   1 
ATOM   383   C CA  . ASN A 1 68  ? -24.253 -15.432 29.579 1.00 37.91  ? 270 ASN A CA  1 
ATOM   384   C C   . ASN A 1 68  ? -24.861 -15.343 30.971 1.00 35.77  ? 270 ASN A C   1 
ATOM   385   O O   . ASN A 1 68  ? -24.181 -14.953 31.927 1.00 34.79  ? 270 ASN A O   1 
ATOM   386   C CB  . ASN A 1 68  ? -24.599 -14.186 28.770 1.00 38.77  ? 270 ASN A CB  1 
ATOM   387   C CG  . ASN A 1 68  ? -23.964 -12.937 29.340 1.00 40.46  ? 270 ASN A CG  1 
ATOM   388   O OD1 . ASN A 1 68  ? -22.887 -12.994 29.935 1.00 39.96  ? 270 ASN A OD1 1 
ATOM   389   N ND2 . ASN A 1 68  ? -24.629 -11.801 29.170 1.00 40.73  ? 270 ASN A ND2 1 
ATOM   390   N N   . ASP A 1 69  ? -26.145 -15.677 31.107 1.00 36.65  ? 271 ASP A N   1 
ATOM   391   C CA  . ASP A 1 69  ? -26.777 -15.642 32.418 1.00 34.28  ? 271 ASP A CA  1 
ATOM   392   C C   . ASP A 1 69  ? -26.221 -16.697 33.360 1.00 31.90  ? 271 ASP A C   1 
ATOM   393   O O   . ASP A 1 69  ? -26.239 -16.490 34.577 1.00 31.74  ? 271 ASP A O   1 
ATOM   394   C CB  . ASP A 1 69  ? -28.288 -15.829 32.285 1.00 31.01  ? 271 ASP A CB  1 
ATOM   395   C CG  . ASP A 1 69  ? -28.964 -14.652 31.621 1.00 33.52  ? 271 ASP A CG  1 
ATOM   396   O OD1 . ASP A 1 69  ? -28.331 -13.582 31.514 1.00 34.26  ? 271 ASP A OD1 1 
ATOM   397   O OD2 . ASP A 1 69  ? -30.134 -14.794 31.211 1.00 34.38  ? 271 ASP A OD2 1 
ATOM   398   N N   . ASN A 1 70  ? -25.736 -17.815 32.831 1.00 33.01  ? 272 ASN A N   1 
ATOM   399   C CA  . ASN A 1 70  ? -25.193 -18.898 33.633 1.00 30.55  ? 272 ASN A CA  1 
ATOM   400   C C   . ASN A 1 70  ? -23.681 -18.834 33.783 1.00 28.53  ? 272 ASN A C   1 
ATOM   401   O O   . ASN A 1 70  ? -23.092 -19.759 34.348 1.00 28.51  ? 272 ASN A O   1 
ATOM   402   C CB  . ASN A 1 70  ? -25.604 -20.243 33.031 1.00 32.41  ? 272 ASN A CB  1 
ATOM   403   C CG  . ASN A 1 70  ? -27.079 -20.535 33.217 1.00 32.73  ? 272 ASN A CG  1 
ATOM   404   O OD1 . ASN A 1 70  ? -27.700 -20.064 34.167 1.00 34.06  ? 272 ASN A OD1 1 
ATOM   405   N ND2 . ASN A 1 70  ? -27.651 -21.297 32.296 1.00 33.68  ? 272 ASN A ND2 1 
ATOM   406   N N   . ALA A 1 71  ? -23.039 -17.786 33.277 1.00 29.80  ? 273 ALA A N   1 
ATOM   407   C CA  . ALA A 1 71  ? -21.594 -17.661 33.384 1.00 27.02  ? 273 ALA A CA  1 
ATOM   408   C C   . ALA A 1 71  ? -21.156 -17.603 34.841 1.00 25.59  ? 273 ALA A C   1 
ATOM   409   O O   . ALA A 1 71  ? -21.811 -16.991 35.687 1.00 25.95  ? 273 ALA A O   1 
ATOM   410   C CB  . ALA A 1 71  ? -21.116 -16.411 32.651 1.00 25.85  ? 273 ALA A CB  1 
ATOM   411   N N   . TYR A 1 72  ? -20.035 -18.259 35.133 1.00 25.04  ? 274 TYR A N   1 
ATOM   412   C CA  . TYR A 1 72  ? -19.476 -18.232 36.477 1.00 22.94  ? 274 TYR A CA  1 
ATOM   413   C C   . TYR A 1 72  ? -17.975 -18.449 36.394 1.00 21.40  ? 274 TYR A C   1 
ATOM   414   O O   . TYR A 1 72  ? -17.461 -19.011 35.425 1.00 20.87  ? 274 TYR A O   1 
ATOM   415   C CB  . TYR A 1 72  ? -20.128 -19.281 37.382 1.00 25.13  ? 274 TYR A CB  1 
ATOM   416   C CG  . TYR A 1 72  ? -19.875 -20.715 36.977 1.00 25.62  ? 274 TYR A CG  1 
ATOM   417   C CD1 . TYR A 1 72  ? -18.811 -21.428 37.506 1.00 26.55  ? 274 TYR A CD1 1 
ATOM   418   C CD2 . TYR A 1 72  ? -20.699 -21.354 36.065 1.00 25.95  ? 274 TYR A CD2 1 
ATOM   419   C CE1 . TYR A 1 72  ? -18.579 -22.732 37.144 1.00 27.11  ? 274 TYR A CE1 1 
ATOM   420   C CE2 . TYR A 1 72  ? -20.474 -22.660 35.698 1.00 26.56  ? 274 TYR A CE2 1 
ATOM   421   C CZ  . TYR A 1 72  ? -19.412 -23.343 36.239 1.00 27.18  ? 274 TYR A CZ  1 
ATOM   422   O OH  . TYR A 1 72  ? -19.182 -24.646 35.874 1.00 27.44  ? 274 TYR A OH  1 
ATOM   423   N N   . PHE A 1 73  ? -17.278 -17.968 37.419 1.00 17.08  ? 275 PHE A N   1 
ATOM   424   C CA  . PHE A 1 73  ? -15.859 -18.217 37.612 1.00 16.39  ? 275 PHE A CA  1 
ATOM   425   C C   . PHE A 1 73  ? -15.611 -18.444 39.092 1.00 16.70  ? 275 PHE A C   1 
ATOM   426   O O   . PHE A 1 73  ? -16.037 -17.641 39.924 1.00 17.21  ? 275 PHE A O   1 
ATOM   427   C CB  . PHE A 1 73  ? -15.004 -17.046 37.120 1.00 14.78  ? 275 PHE A CB  1 
ATOM   428   C CG  . PHE A 1 73  ? -13.548 -17.202 37.419 1.00 14.58  ? 275 PHE A CG  1 
ATOM   429   C CD1 . PHE A 1 73  ? -12.728 -17.888 36.554 1.00 14.86  ? 275 PHE A CD1 1 
ATOM   430   C CD2 . PHE A 1 73  ? -13.006 -16.697 38.586 1.00 14.85  ? 275 PHE A CD2 1 
ATOM   431   C CE1 . PHE A 1 73  ? -11.396 -18.044 36.834 1.00 14.60  ? 275 PHE A CE1 1 
ATOM   432   C CE2 . PHE A 1 73  ? -11.679 -16.863 38.871 1.00 15.19  ? 275 PHE A CE2 1 
ATOM   433   C CZ  . PHE A 1 73  ? -10.874 -17.539 37.995 1.00 15.45  ? 275 PHE A CZ  1 
ATOM   434   N N   . GLY A 1 74  ? -14.905 -19.515 39.422 1.00 14.36  ? 276 GLY A N   1 
ATOM   435   C CA  . GLY A 1 74  ? -14.676 -19.820 40.818 1.00 13.66  ? 276 GLY A CA  1 
ATOM   436   C C   . GLY A 1 74  ? -13.674 -20.932 40.999 1.00 14.16  ? 276 GLY A C   1 
ATOM   437   O O   . GLY A 1 74  ? -12.951 -21.299 40.072 1.00 15.15  ? 276 GLY A O   1 
ATOM   438   N N   . TYR A 1 75  ? -13.640 -21.464 42.218 1.00 14.14  ? 277 TYR A N   1 
ATOM   439   C CA  . TYR A 1 75  ? -12.665 -22.472 42.600 1.00 13.71  ? 277 TYR A CA  1 
ATOM   440   C C   . TYR A 1 75  ? -13.343 -23.598 43.358 1.00 14.02  ? 277 TYR A C   1 
ATOM   441   O O   . TYR A 1 75  ? -14.303 -23.374 44.099 1.00 14.42  ? 277 TYR A O   1 
ATOM   442   C CB  . TYR A 1 75  ? -11.548 -21.872 43.460 1.00 12.01  ? 277 TYR A CB  1 
ATOM   443   C CG  . TYR A 1 75  ? -10.682 -20.900 42.706 1.00 12.43  ? 277 TYR A CG  1 
ATOM   444   C CD1 . TYR A 1 75  ? -9.573  -21.335 42.001 1.00 13.65  ? 277 TYR A CD1 1 
ATOM   445   C CD2 . TYR A 1 75  ? -10.983 -19.548 42.682 1.00 11.61  ? 277 TYR A CD2 1 
ATOM   446   C CE1 . TYR A 1 75  ? -8.787  -20.457 41.306 1.00 15.63  ? 277 TYR A CE1 1 
ATOM   447   C CE2 . TYR A 1 75  ? -10.200 -18.662 41.986 1.00 13.17  ? 277 TYR A CE2 1 
ATOM   448   C CZ  . TYR A 1 75  ? -9.105  -19.124 41.303 1.00 15.21  ? 277 TYR A CZ  1 
ATOM   449   O OH  . TYR A 1 75  ? -8.318  -18.246 40.606 1.00 17.27  ? 277 TYR A OH  1 
ATOM   450   N N   . SER A 1 76  ? -12.832 -24.806 43.162 1.00 13.16  ? 278 SER A N   1 
ATOM   451   C CA  . SER A 1 76  ? -13.283 -25.985 43.879 1.00 13.99  ? 278 SER A CA  1 
ATOM   452   C C   . SER A 1 76  ? -12.155 -26.490 44.764 1.00 14.41  ? 278 SER A C   1 
ATOM   453   O O   . SER A 1 76  ? -11.014 -26.625 44.317 1.00 14.73  ? 278 SER A O   1 
ATOM   454   C CB  . SER A 1 76  ? -13.721 -27.078 42.908 1.00 14.35  ? 278 SER A CB  1 
ATOM   455   O OG  . SER A 1 76  ? -12.631 -27.530 42.131 1.00 16.04  ? 278 SER A OG  1 
ATOM   456   N N   . THR A 1 77  ? -12.482 -26.781 46.013 1.00 17.13  ? 279 THR A N   1 
ATOM   457   C CA  . THR A 1 77  ? -11.498 -27.074 47.037 1.00 16.82  ? 279 THR A CA  1 
ATOM   458   C C   . THR A 1 77  ? -11.620 -28.525 47.478 1.00 16.93  ? 279 THR A C   1 
ATOM   459   O O   . THR A 1 77  ? -12.692 -29.129 47.366 1.00 18.28  ? 279 THR A O   1 
ATOM   460   C CB  . THR A 1 77  ? -11.694 -26.155 48.251 1.00 18.81  ? 279 THR A CB  1 
ATOM   461   O OG1 . THR A 1 77  ? -12.938 -26.463 48.884 1.00 18.77  ? 279 THR A OG1 1 
ATOM   462   C CG2 . THR A 1 77  ? -11.742 -24.712 47.805 1.00 16.29  ? 279 THR A CG2 1 
ATOM   463   N N   . PRO A 1 78  ? -10.534 -29.124 47.977 1.00 22.01  ? 280 PRO A N   1 
ATOM   464   C CA  . PRO A 1 78  ? -10.632 -30.484 48.527 1.00 21.85  ? 280 PRO A CA  1 
ATOM   465   C C   . PRO A 1 78  ? -11.442 -30.571 49.807 1.00 22.03  ? 280 PRO A C   1 
ATOM   466   O O   . PRO A 1 78  ? -11.825 -31.679 50.200 1.00 23.83  ? 280 PRO A O   1 
ATOM   467   C CB  . PRO A 1 78  ? -9.168  -30.866 48.770 1.00 20.56  ? 280 PRO A CB  1 
ATOM   468   C CG  . PRO A 1 78  ? -8.478  -29.563 48.966 1.00 20.28  ? 280 PRO A CG  1 
ATOM   469   C CD  . PRO A 1 78  ? -9.156  -28.611 48.028 1.00 20.65  ? 280 PRO A CD  1 
ATOM   470   N N   . TRP A 1 79  ? -11.709 -29.449 50.464 1.00 23.48  ? 281 TRP A N   1 
ATOM   471   C CA  . TRP A 1 79  ? -12.406 -29.435 51.739 1.00 22.94  ? 281 TRP A CA  1 
ATOM   472   C C   . TRP A 1 79  ? -13.875 -29.806 51.572 1.00 23.32  ? 281 TRP A C   1 
ATOM   473   O O   . TRP A 1 79  ? -14.494 -29.536 50.541 1.00 24.08  ? 281 TRP A O   1 
ATOM   474   C CB  . TRP A 1 79  ? -12.301 -28.047 52.371 1.00 23.36  ? 281 TRP A CB  1 
ATOM   475   C CG  . TRP A 1 79  ? -10.929 -27.668 52.813 1.00 24.30  ? 281 TRP A CG  1 
ATOM   476   C CD1 . TRP A 1 79  ? -9.952  -27.103 52.050 1.00 25.03  ? 281 TRP A CD1 1 
ATOM   477   C CD2 . TRP A 1 79  ? -10.403 -27.754 54.138 1.00 25.04  ? 281 TRP A CD2 1 
ATOM   478   N NE1 . TRP A 1 79  ? -8.835  -26.871 52.809 1.00 25.58  ? 281 TRP A NE1 1 
ATOM   479   C CE2 . TRP A 1 79  ? -9.090  -27.254 54.099 1.00 24.71  ? 281 TRP A CE2 1 
ATOM   480   C CE3 . TRP A 1 79  ? -10.910 -28.219 55.353 1.00 25.72  ? 281 TRP A CE3 1 
ATOM   481   C CZ2 . TRP A 1 79  ? -8.275  -27.209 55.225 1.00 24.67  ? 281 TRP A CZ2 1 
ATOM   482   C CZ3 . TRP A 1 79  ? -10.100 -28.173 56.468 1.00 26.32  ? 281 TRP A CZ3 1 
ATOM   483   C CH2 . TRP A 1 79  ? -8.797  -27.675 56.397 1.00 26.48  ? 281 TRP A CH2 1 
ATOM   484   N N   . GLY A 1 80  ? -14.426 -30.450 52.602 1.00 25.70  ? 282 GLY A N   1 
ATOM   485   C CA  . GLY A 1 80  ? -15.852 -30.622 52.743 1.00 25.89  ? 282 GLY A CA  1 
ATOM   486   C C   . GLY A 1 80  ? -16.380 -29.713 53.842 1.00 26.56  ? 282 GLY A C   1 
ATOM   487   O O   . GLY A 1 80  ? -15.625 -29.044 54.543 1.00 26.06  ? 282 GLY A O   1 
ATOM   488   N N   . TYR A 1 81  ? -17.702 -29.705 53.993 1.00 29.84  ? 283 TYR A N   1 
ATOM   489   C CA  . TYR A 1 81  ? -18.304 -28.861 55.015 1.00 30.18  ? 283 TYR A CA  1 
ATOM   490   C C   . TYR A 1 81  ? -19.610 -29.471 55.504 1.00 31.44  ? 283 TYR A C   1 
ATOM   491   O O   . TYR A 1 81  ? -20.315 -30.151 54.756 1.00 31.59  ? 283 TYR A O   1 
ATOM   492   C CB  . TYR A 1 81  ? -18.530 -27.433 54.497 1.00 28.25  ? 283 TYR A CB  1 
ATOM   493   C CG  . TYR A 1 81  ? -19.538 -27.308 53.381 1.00 29.24  ? 283 TYR A CG  1 
ATOM   494   C CD1 . TYR A 1 81  ? -20.863 -27.002 53.648 1.00 29.91  ? 283 TYR A CD1 1 
ATOM   495   C CD2 . TYR A 1 81  ? -19.167 -27.506 52.061 1.00 29.78  ? 283 TYR A CD2 1 
ATOM   496   C CE1 . TYR A 1 81  ? -21.786 -26.885 52.633 1.00 31.24  ? 283 TYR A CE1 1 
ATOM   497   C CE2 . TYR A 1 81  ? -20.085 -27.394 51.039 1.00 30.96  ? 283 TYR A CE2 1 
ATOM   498   C CZ  . TYR A 1 81  ? -21.392 -27.082 51.330 1.00 31.38  ? 283 TYR A CZ  1 
ATOM   499   O OH  . TYR A 1 81  ? -22.310 -26.970 50.313 1.00 30.87  ? 283 TYR A OH  1 
ATOM   500   N N   . PHE A 1 82  ? -19.919 -29.214 56.772 1.00 30.28  ? 284 PHE A N   1 
ATOM   501   C CA  . PHE A 1 82  ? -21.160 -29.664 57.387 1.00 31.73  ? 284 PHE A CA  1 
ATOM   502   C C   . PHE A 1 82  ? -22.237 -28.600 57.251 1.00 34.74  ? 284 PHE A C   1 
ATOM   503   O O   . PHE A 1 82  ? -21.993 -27.417 57.499 1.00 35.89  ? 284 PHE A O   1 
ATOM   504   C CB  . PHE A 1 82  ? -20.949 -29.976 58.868 1.00 34.24  ? 284 PHE A CB  1 
ATOM   505   C CG  . PHE A 1 82  ? -20.004 -31.102 59.118 1.00 34.80  ? 284 PHE A CG  1 
ATOM   506   C CD1 . PHE A 1 82  ? -20.443 -32.409 59.075 1.00 34.13  ? 284 PHE A CD1 1 
ATOM   507   C CD2 . PHE A 1 82  ? -18.675 -30.855 59.398 1.00 35.37  ? 284 PHE A CD2 1 
ATOM   508   C CE1 . PHE A 1 82  ? -19.574 -33.448 59.303 1.00 34.87  ? 284 PHE A CE1 1 
ATOM   509   C CE2 . PHE A 1 82  ? -17.802 -31.893 59.631 1.00 35.65  ? 284 PHE A CE2 1 
ATOM   510   C CZ  . PHE A 1 82  ? -18.252 -33.191 59.583 1.00 35.65  ? 284 PHE A CZ  1 
ATOM   511   N N   . ASP A 1 83  ? -23.435 -29.028 56.860 1.00 41.45  ? 285 ASP A N   1 
ATOM   512   C CA  . ASP A 1 83  ? -24.583 -28.135 56.768 1.00 43.12  ? 285 ASP A CA  1 
ATOM   513   C C   . ASP A 1 83  ? -25.743 -28.764 57.529 1.00 40.64  ? 285 ASP A C   1 
ATOM   514   O O   . ASP A 1 83  ? -26.291 -29.781 57.099 1.00 41.19  ? 285 ASP A O   1 
ATOM   515   C CB  . ASP A 1 83  ? -24.951 -27.890 55.305 1.00 40.07  ? 285 ASP A CB  1 
ATOM   516   C CG  . ASP A 1 83  ? -25.997 -26.820 55.142 1.00 46.43  ? 285 ASP A CG  1 
ATOM   517   O OD1 . ASP A 1 83  ? -26.352 -26.194 56.156 1.00 50.89  ? 285 ASP A OD1 1 
ATOM   518   O OD2 . ASP A 1 83  ? -26.466 -26.608 54.004 1.00 49.82  ? 285 ASP A OD2 1 
ATOM   519   N N   . PHE A 1 84  ? -26.179 -28.075 58.574 1.00 43.94  ? 286 PHE A N   1 
ATOM   520   C CA  . PHE A 1 84  ? -27.321 -28.488 59.365 1.00 41.33  ? 286 PHE A CA  1 
ATOM   521   C C   . PHE A 1 84  ? -28.365 -27.370 59.384 1.00 39.39  ? 286 PHE A C   1 
ATOM   522   O O   . PHE A 1 84  ? -29.113 -27.234 60.341 1.00 38.92  ? 286 PHE A O   1 
ATOM   523   C CB  . PHE A 1 84  ? -26.901 -28.867 60.786 1.00 39.61  ? 286 PHE A CB  1 
ATOM   524   C CG  . PHE A 1 84  ? -26.003 -27.864 61.454 1.00 40.11  ? 286 PHE A CG  1 
ATOM   525   C CD1 . PHE A 1 84  ? -26.533 -26.837 62.214 1.00 40.64  ? 286 PHE A CD1 1 
ATOM   526   C CD2 . PHE A 1 84  ? -24.630 -27.968 61.351 1.00 40.36  ? 286 PHE A CD2 1 
ATOM   527   C CE1 . PHE A 1 84  ? -25.710 -25.923 62.841 1.00 40.43  ? 286 PHE A CE1 1 
ATOM   528   C CE2 . PHE A 1 84  ? -23.802 -27.057 61.974 1.00 41.14  ? 286 PHE A CE2 1 
ATOM   529   C CZ  . PHE A 1 84  ? -24.342 -26.034 62.721 1.00 40.51  ? 286 PHE A CZ  1 
ATOM   530   N N   . ASN A 1 85  ? -28.394 -26.565 58.323 1.00 37.72  ? 287 ASN A N   1 
ATOM   531   C CA  . ASN A 1 85  ? -29.331 -25.443 58.194 1.00 36.57  ? 287 ASN A CA  1 
ATOM   532   C C   . ASN A 1 85  ? -30.802 -25.827 58.113 1.00 36.29  ? 287 ASN A C   1 
ATOM   533   O O   . ASN A 1 85  ? -31.644 -25.166 58.700 1.00 37.09  ? 287 ASN A O   1 
ATOM   534   C CB  . ASN A 1 85  ? -28.983 -24.572 56.989 1.00 34.69  ? 287 ASN A CB  1 
ATOM   535   C CG  . ASN A 1 85  ? -29.370 -23.128 57.178 1.00 35.48  ? 287 ASN A CG  1 
ATOM   536   O OD1 . ASN A 1 85  ? -30.119 -22.792 58.083 1.00 34.06  ? 287 ASN A OD1 1 
ATOM   537   N ND2 . ASN A 1 85  ? -28.857 -22.264 56.316 1.00 37.93  ? 287 ASN A ND2 1 
ATOM   538   N N   . ARG A 1 86  ? -31.113 -26.906 57.410 1.00 36.65  ? 288 ARG A N   1 
ATOM   539   C CA  . ARG A 1 86  ? -32.499 -27.318 57.237 1.00 36.72  ? 288 ARG A CA  1 
ATOM   540   C C   . ARG A 1 86  ? -33.181 -27.617 58.562 1.00 36.97  ? 288 ARG A C   1 
ATOM   541   O O   . ARG A 1 86  ? -32.575 -28.134 59.485 1.00 37.07  ? 288 ARG A O   1 
ATOM   542   C CB  . ARG A 1 86  ? -32.595 -28.512 56.292 1.00 35.56  ? 288 ARG A CB  1 
ATOM   543   C CG  . ARG A 1 86  ? -32.045 -28.223 54.909 1.00 36.07  ? 288 ARG A CG  1 
ATOM   544   C CD  . ARG A 1 86  ? -32.240 -29.392 53.969 1.00 36.95  ? 288 ARG A CD  1 
ATOM   545   N NE  . ARG A 1 86  ? -33.608 -29.463 53.488 1.00 38.27  ? 288 ARG A NE  1 
ATOM   546   C CZ  . ARG A 1 86  ? -34.027 -30.323 52.574 1.00 39.14  ? 288 ARG A CZ  1 
ATOM   547   N NH1 . ARG A 1 86  ? -33.183 -31.188 52.040 1.00 38.72  ? 288 ARG A NH1 1 
ATOM   548   N NH2 . ARG A 1 86  ? -35.290 -30.317 52.191 1.00 37.22  ? 288 ARG A NH2 1 
ATOM   549   N N   . PHE A 1 87  ? -34.457 -27.267 58.644 1.00 38.71  ? 289 PHE A N   1 
ATOM   550   C CA  . PHE A 1 87  ? -35.228 -27.450 59.863 1.00 39.43  ? 289 PHE A CA  1 
ATOM   551   C C   . PHE A 1 87  ? -35.352 -28.895 60.295 1.00 40.74  ? 289 PHE A C   1 
ATOM   552   O O   . PHE A 1 87  ? -35.273 -29.192 61.479 1.00 40.33  ? 289 PHE A O   1 
ATOM   553   C CB  . PHE A 1 87  ? -36.612 -26.817 59.742 1.00 36.91  ? 289 PHE A CB  1 
ATOM   554   C CG  . PHE A 1 87  ? -36.643 -25.365 60.108 1.00 37.22  ? 289 PHE A CG  1 
ATOM   555   C CD1 . PHE A 1 87  ? -36.268 -24.954 61.371 1.00 36.28  ? 289 PHE A CD1 1 
ATOM   556   C CD2 . PHE A 1 87  ? -37.048 -24.416 59.193 1.00 36.82  ? 289 PHE A CD2 1 
ATOM   557   C CE1 . PHE A 1 87  ? -36.290 -23.620 61.714 1.00 36.69  ? 289 PHE A CE1 1 
ATOM   558   C CE2 . PHE A 1 87  ? -37.073 -23.081 59.529 1.00 36.31  ? 289 PHE A CE2 1 
ATOM   559   C CZ  . PHE A 1 87  ? -36.695 -22.684 60.791 1.00 36.01  ? 289 PHE A CZ  1 
ATOM   560   N N   . HIS A 1 88  ? -35.499 -29.809 59.344 1.00 41.39  ? 290 HIS A N   1 
ATOM   561   C CA  . HIS A 1 88  ? -35.670 -31.221 59.685 1.00 43.12  ? 290 HIS A CA  1 
ATOM   562   C C   . HIS A 1 88  ? -34.504 -31.909 60.399 1.00 44.21  ? 290 HIS A C   1 
ATOM   563   O O   . HIS A 1 88  ? -34.707 -32.923 61.054 1.00 45.68  ? 290 HIS A O   1 
ATOM   564   C CB  . HIS A 1 88  ? -36.256 -32.067 58.540 1.00 39.16  ? 290 HIS A CB  1 
ATOM   565   C CG  . HIS A 1 88  ? -35.400 -32.148 57.319 1.00 40.37  ? 290 HIS A CG  1 
ATOM   566   N ND1 . HIS A 1 88  ? -34.026 -32.166 57.367 1.00 42.32  ? 290 HIS A ND1 1 
ATOM   567   C CD2 . HIS A 1 88  ? -35.732 -32.269 56.013 1.00 40.03  ? 290 HIS A CD2 1 
ATOM   568   C CE1 . HIS A 1 88  ? -33.546 -32.269 56.142 1.00 41.58  ? 290 HIS A CE1 1 
ATOM   569   N NE2 . HIS A 1 88  ? -34.561 -32.334 55.302 1.00 40.81  ? 290 HIS A NE2 1 
ATOM   570   N N   . CYS A 1 89  ? -33.291 -31.386 60.274 1.00 42.34  ? 291 CYS A N   1 
ATOM   571   C CA  . CYS A 1 89  ? -32.171 -32.001 60.949 1.00 44.23  ? 291 CYS A CA  1 
ATOM   572   C C   . CYS A 1 89  ? -32.385 -32.012 62.460 1.00 43.18  ? 291 CYS A C   1 
ATOM   573   O O   . CYS A 1 89  ? -32.155 -33.028 63.086 1.00 42.55  ? 291 CYS A O   1 
ATOM   574   C CB  . CYS A 1 89  ? -30.879 -31.239 60.652 1.00 40.65  ? 291 CYS A CB  1 
ATOM   575   S SG  . CYS A 1 89  ? -30.609 -30.747 58.934 1.00 49.48  ? 291 CYS A SG  1 
ATOM   576   N N   . HIS A 1 90  ? -32.885 -30.920 63.036 1.00 45.26  ? 292 HIS A N   1 
ATOM   577   C CA  . HIS A 1 90  ? -33.060 -30.819 64.494 1.00 44.19  ? 292 HIS A CA  1 
ATOM   578   C C   . HIS A 1 90  ? -34.458 -31.062 65.081 1.00 43.92  ? 292 HIS A C   1 
ATOM   579   O O   . HIS A 1 90  ? -34.627 -31.050 66.293 1.00 45.28  ? 292 HIS A O   1 
ATOM   580   C CB  . HIS A 1 90  ? -32.570 -29.450 64.977 1.00 42.96  ? 292 HIS A CB  1 
ATOM   581   C CG  . HIS A 1 90  ? -31.518 -28.843 64.106 1.00 44.01  ? 292 HIS A CG  1 
ATOM   582   N ND1 . HIS A 1 90  ? -30.201 -28.739 64.492 1.00 45.48  ? 292 HIS A ND1 1 
ATOM   583   C CD2 . HIS A 1 90  ? -31.589 -28.312 62.864 1.00 44.31  ? 292 HIS A CD2 1 
ATOM   584   C CE1 . HIS A 1 90  ? -29.505 -28.168 63.526 1.00 46.03  ? 292 HIS A CE1 1 
ATOM   585   N NE2 . HIS A 1 90  ? -30.324 -27.900 62.527 1.00 45.19  ? 292 HIS A NE2 1 
ATOM   586   N N   . PHE A 1 91  ? -35.453 -31.266 64.234 1.00 45.42  ? 293 PHE A N   1 
ATOM   587   C CA  . PHE A 1 91  ? -36.818 -31.499 64.683 1.00 44.45  ? 293 PHE A CA  1 
ATOM   588   C C   . PHE A 1 91  ? -37.373 -32.748 64.023 1.00 44.89  ? 293 PHE A C   1 
ATOM   589   O O   . PHE A 1 91  ? -37.174 -32.962 62.823 1.00 46.50  ? 293 PHE A O   1 
ATOM   590   C CB  . PHE A 1 91  ? -37.725 -30.303 64.371 1.00 44.27  ? 293 PHE A CB  1 
ATOM   591   C CG  . PHE A 1 91  ? -37.427 -29.084 65.188 1.00 44.00  ? 293 PHE A CG  1 
ATOM   592   C CD1 . PHE A 1 91  ? -37.988 -28.926 66.442 1.00 44.10  ? 293 PHE A CD1 1 
ATOM   593   C CD2 . PHE A 1 91  ? -36.586 -28.098 64.707 1.00 44.48  ? 293 PHE A CD2 1 
ATOM   594   C CE1 . PHE A 1 91  ? -37.719 -27.808 67.199 1.00 44.34  ? 293 PHE A CE1 1 
ATOM   595   C CE2 . PHE A 1 91  ? -36.312 -26.979 65.461 1.00 45.03  ? 293 PHE A CE2 1 
ATOM   596   C CZ  . PHE A 1 91  ? -36.880 -26.834 66.708 1.00 44.74  ? 293 PHE A CZ  1 
ATOM   597   N N   . SER A 1 92  ? -38.059 -33.567 64.812 1.00 43.73  ? 294 SER A N   1 
ATOM   598   C CA  . SER A 1 92  ? -38.806 -34.685 64.273 1.00 43.10  ? 294 SER A CA  1 
ATOM   599   C C   . SER A 1 92  ? -40.192 -34.214 63.840 1.00 42.36  ? 294 SER A C   1 
ATOM   600   O O   . SER A 1 92  ? -40.633 -33.129 64.223 1.00 41.18  ? 294 SER A O   1 
ATOM   601   C CB  . SER A 1 92  ? -38.922 -35.795 65.313 1.00 41.65  ? 294 SER A CB  1 
ATOM   602   O OG  . SER A 1 92  ? -39.667 -35.369 66.437 1.00 42.87  ? 294 SER A OG  1 
ATOM   603   N N   . PRO A 1 93  ? -40.889 -35.001 63.016 1.00 41.17  ? 295 PRO A N   1 
ATOM   604   C CA  . PRO A 1 93  ? -42.285 -34.656 62.696 1.00 41.25  ? 295 PRO A CA  1 
ATOM   605   C C   . PRO A 1 93  ? -43.180 -34.515 63.918 1.00 42.03  ? 295 PRO A C   1 
ATOM   606   O O   . PRO A 1 93  ? -44.151 -33.751 63.878 1.00 41.34  ? 295 PRO A O   1 
ATOM   607   C CB  . PRO A 1 93  ? -42.720 -35.815 61.793 1.00 38.13  ? 295 PRO A CB  1 
ATOM   608   C CG  . PRO A 1 93  ? -41.467 -36.241 61.128 1.00 39.36  ? 295 PRO A CG  1 
ATOM   609   C CD  . PRO A 1 93  ? -40.382 -36.083 62.155 1.00 38.90  ? 295 PRO A CD  1 
ATOM   610   N N   . ARG A 1 94  ? -42.883 -35.228 65.005 1.00 42.94  ? 296 ARG A N   1 
ATOM   611   C CA  . ARG A 1 94  ? -43.649 -35.039 66.233 1.00 44.85  ? 296 ARG A CA  1 
ATOM   612   C C   . ARG A 1 94  ? -43.185 -33.795 66.980 1.00 44.52  ? 296 ARG A C   1 
ATOM   613   O O   . ARG A 1 94  ? -43.999 -33.074 67.568 1.00 43.91  ? 296 ARG A O   1 
ATOM   614   C CB  . ARG A 1 94  ? -43.530 -36.274 67.125 1.00 40.93  ? 296 ARG A CB  1 
ATOM   615   C CG  . ARG A 1 94  ? -44.288 -36.182 68.440 1.00 44.33  ? 296 ARG A CG  1 
ATOM   616   C CD  . ARG A 1 94  ? -45.788 -36.138 68.218 1.00 48.50  ? 296 ARG A CD  1 
ATOM   617   N NE  . ARG A 1 94  ? -46.521 -36.087 69.479 1.00 54.49  ? 296 ARG A NE  1 
ATOM   618   C CZ  . ARG A 1 94  ? -46.861 -34.967 70.108 1.00 56.60  ? 296 ARG A CZ  1 
ATOM   619   N NH1 . ARG A 1 94  ? -46.553 -33.789 69.587 1.00 56.17  ? 296 ARG A NH1 1 
ATOM   620   N NH2 . ARG A 1 94  ? -47.521 -35.024 71.255 1.00 56.39  ? 296 ARG A NH2 1 
ATOM   621   N N   . ASP A 1 95  ? -41.876 -33.528 66.971 1.00 45.25  ? 297 ASP A N   1 
ATOM   622   C CA  . ASP A 1 95  ? -41.360 -32.324 67.616 1.00 46.06  ? 297 ASP A CA  1 
ATOM   623   C C   . ASP A 1 95  ? -41.792 -31.071 66.870 1.00 44.24  ? 297 ASP A C   1 
ATOM   624   O O   . ASP A 1 95  ? -41.943 -30.002 67.471 1.00 43.85  ? 297 ASP A O   1 
ATOM   625   C CB  . ASP A 1 95  ? -39.836 -32.385 67.707 1.00 45.83  ? 297 ASP A CB  1 
ATOM   626   C CG  . ASP A 1 95  ? -39.351 -33.404 68.712 1.00 51.43  ? 297 ASP A CG  1 
ATOM   627   O OD1 . ASP A 1 95  ? -40.154 -33.826 69.569 1.00 53.07  ? 297 ASP A OD1 1 
ATOM   628   O OD2 . ASP A 1 95  ? -38.165 -33.788 68.642 1.00 54.56  ? 297 ASP A OD2 1 
ATOM   629   N N   . TRP A 1 96  ? -41.980 -31.179 65.554 1.00 44.66  ? 298 TRP A N   1 
ATOM   630   C CA  . TRP A 1 96  ? -42.443 -30.032 64.782 1.00 43.78  ? 298 TRP A CA  1 
ATOM   631   C C   . TRP A 1 96  ? -43.926 -29.791 65.009 1.00 43.90  ? 298 TRP A C   1 
ATOM   632   O O   . TRP A 1 96  ? -44.402 -28.656 64.906 1.00 43.59  ? 298 TRP A O   1 
ATOM   633   C CB  . TRP A 1 96  ? -42.154 -30.252 63.301 1.00 40.36  ? 298 TRP A CB  1 
ATOM   634   C CG  . TRP A 1 96  ? -42.544 -29.110 62.415 1.00 39.43  ? 298 TRP A CG  1 
ATOM   635   C CD1 . TRP A 1 96  ? -43.641 -29.034 61.614 1.00 39.02  ? 298 TRP A CD1 1 
ATOM   636   C CD2 . TRP A 1 96  ? -41.819 -27.891 62.219 1.00 40.22  ? 298 TRP A CD2 1 
ATOM   637   N NE1 . TRP A 1 96  ? -43.653 -27.840 60.938 1.00 39.92  ? 298 TRP A NE1 1 
ATOM   638   C CE2 . TRP A 1 96  ? -42.544 -27.120 61.292 1.00 40.14  ? 298 TRP A CE2 1 
ATOM   639   C CE3 . TRP A 1 96  ? -40.631 -27.374 62.741 1.00 40.29  ? 298 TRP A CE3 1 
ATOM   640   C CZ2 . TRP A 1 96  ? -42.120 -25.861 60.877 1.00 39.84  ? 298 TRP A CZ2 1 
ATOM   641   C CZ3 . TRP A 1 96  ? -40.212 -26.125 62.327 1.00 40.30  ? 298 TRP A CZ3 1 
ATOM   642   C CH2 . TRP A 1 96  ? -40.954 -25.383 61.404 1.00 40.10  ? 298 TRP A CH2 1 
ATOM   643   N N   . GLN A 1 97  ? -44.673 -30.851 65.322 1.00 43.53  ? 299 GLN A N   1 
ATOM   644   C CA  . GLN A 1 97  ? -46.090 -30.699 65.629 1.00 44.10  ? 299 GLN A CA  1 
ATOM   645   C C   . GLN A 1 97  ? -46.285 -30.104 67.015 1.00 45.60  ? 299 GLN A C   1 
ATOM   646   O O   . GLN A 1 97  ? -47.198 -29.303 67.238 1.00 45.87  ? 299 GLN A O   1 
ATOM   647   C CB  . GLN A 1 97  ? -46.794 -32.049 65.525 1.00 48.11  ? 299 GLN A CB  1 
ATOM   648   C CG  . GLN A 1 97  ? -48.290 -31.982 65.739 1.00 47.97  ? 299 GLN A CG  1 
ATOM   649   C CD  . GLN A 1 97  ? -48.960 -33.314 65.507 1.00 49.53  ? 299 GLN A CD  1 
ATOM   650   O OE1 . GLN A 1 97  ? -48.317 -34.280 65.101 1.00 50.96  ? 299 GLN A OE1 1 
ATOM   651   N NE2 . GLN A 1 97  ? -50.258 -33.377 65.763 1.00 49.48  ? 299 GLN A NE2 1 
ATOM   652   N N   . ARG A 1 98  ? -45.436 -30.495 67.965 1.00 46.96  ? 300 ARG A N   1 
ATOM   653   C CA  . ARG A 1 98  ? -45.503 -29.907 69.297 1.00 49.51  ? 300 ARG A CA  1 
ATOM   654   C C   . ARG A 1 98  ? -45.113 -28.435 69.265 1.00 48.09  ? 300 ARG A C   1 
ATOM   655   O O   . ARG A 1 98  ? -45.550 -27.655 70.118 1.00 48.08  ? 300 ARG A O   1 
ATOM   656   C CB  . ARG A 1 98  ? -44.600 -30.687 70.254 1.00 40.41  ? 300 ARG A CB  1 
ATOM   657   C CG  . ARG A 1 98  ? -44.688 -30.246 71.701 1.00 48.87  ? 300 ARG A CG  1 
ATOM   658   C CD  . ARG A 1 98  ? -43.889 -31.157 72.620 1.00 57.39  ? 300 ARG A CD  1 
ATOM   659   N NE  . ARG A 1 98  ? -44.407 -32.521 72.658 1.00 67.32  ? 300 ARG A NE  1 
ATOM   660   C CZ  . ARG A 1 98  ? -43.816 -33.563 72.081 1.00 71.53  ? 300 ARG A CZ  1 
ATOM   661   N NH1 . ARG A 1 98  ? -42.678 -33.401 71.420 1.00 72.02  ? 300 ARG A NH1 1 
ATOM   662   N NH2 . ARG A 1 98  ? -44.361 -34.769 72.170 1.00 71.87  ? 300 ARG A NH2 1 
ATOM   663   N N   . LEU A 1 99  ? -44.296 -28.041 68.287 1.00 49.43  ? 301 LEU A N   1 
ATOM   664   C CA  . LEU A 1 99  ? -43.858 -26.654 68.182 1.00 47.98  ? 301 LEU A CA  1 
ATOM   665   C C   . LEU A 1 99  ? -44.952 -25.758 67.614 1.00 48.60  ? 301 LEU A C   1 
ATOM   666   O O   . LEU A 1 99  ? -45.284 -24.721 68.198 1.00 48.75  ? 301 LEU A O   1 
ATOM   667   C CB  . LEU A 1 99  ? -42.605 -26.576 67.312 1.00 47.22  ? 301 LEU A CB  1 
ATOM   668   C CG  . LEU A 1 99  ? -42.089 -25.180 66.969 1.00 47.05  ? 301 LEU A CG  1 
ATOM   669   C CD1 . LEU A 1 99  ? -41.677 -24.455 68.220 1.00 46.39  ? 301 LEU A CD1 1 
ATOM   670   C CD2 . LEU A 1 99  ? -40.931 -25.263 65.996 1.00 47.19  ? 301 LEU A CD2 1 
ATOM   671   N N   . ILE A 1 100 ? -45.533 -26.148 66.478 1.00 50.50  ? 302 ILE A N   1 
ATOM   672   C CA  . ILE A 1 100 ? -46.368 -25.222 65.723 1.00 50.08  ? 302 ILE A CA  1 
ATOM   673   C C   . ILE A 1 100 ? -47.783 -25.111 66.270 1.00 49.74  ? 302 ILE A C   1 
ATOM   674   O O   . ILE A 1 100 ? -48.460 -24.110 66.005 1.00 50.99  ? 302 ILE A O   1 
ATOM   675   C CB  . ILE A 1 100 ? -46.418 -25.630 64.243 1.00 41.60  ? 302 ILE A CB  1 
ATOM   676   C CG1 . ILE A 1 100 ? -47.055 -27.008 64.086 1.00 43.86  ? 302 ILE A CG1 1 
ATOM   677   C CG2 . ILE A 1 100 ? -45.025 -25.636 63.656 1.00 44.23  ? 302 ILE A CG2 1 
ATOM   678   C CD1 . ILE A 1 100 ? -47.285 -27.404 62.650 1.00 47.77  ? 302 ILE A CD1 1 
ATOM   679   N N   . ASN A 1 101 ? -48.263 -26.105 67.015 1.00 51.92  ? 303 ASN A N   1 
ATOM   680   C CA  . ASN A 1 101 ? -49.613 -26.026 67.557 1.00 51.71  ? 303 ASN A CA  1 
ATOM   681   C C   . ASN A 1 101 ? -49.700 -25.201 68.832 1.00 52.21  ? 303 ASN A C   1 
ATOM   682   O O   . ASN A 1 101 ? -50.678 -24.468 69.008 1.00 52.55  ? 303 ASN A O   1 
ATOM   683   C CB  . ASN A 1 101 ? -50.167 -27.426 67.821 1.00 52.78  ? 303 ASN A CB  1 
ATOM   684   C CG  . ASN A 1 101 ? -50.543 -28.155 66.548 1.00 52.92  ? 303 ASN A CG  1 
ATOM   685   O OD1 . ASN A 1 101 ? -50.783 -27.537 65.514 1.00 52.05  ? 303 ASN A OD1 1 
ATOM   686   N ND2 . ASN A 1 101 ? -50.613 -29.476 66.623 1.00 51.46  ? 303 ASN A ND2 1 
ATOM   687   N N   . ASN A 1 102 ? -48.722 -25.310 69.727 1.00 52.86  ? 304 ASN A N   1 
ATOM   688   C CA  . ASN A 1 102 ? -48.800 -24.681 71.037 1.00 53.33  ? 304 ASN A CA  1 
ATOM   689   C C   . ASN A 1 102 ? -48.056 -23.357 71.143 1.00 53.69  ? 304 ASN A C   1 
ATOM   690   O O   . ASN A 1 102 ? -48.080 -22.742 72.213 1.00 54.11  ? 304 ASN A O   1 
ATOM   691   C CB  . ASN A 1 102 ? -48.275 -25.644 72.107 1.00 52.87  ? 304 ASN A CB  1 
ATOM   692   C CG  . ASN A 1 102 ? -49.182 -26.835 72.305 1.00 55.86  ? 304 ASN A CG  1 
ATOM   693   O OD1 . ASN A 1 102 ? -50.222 -26.738 72.956 1.00 59.29  ? 304 ASN A OD1 1 
ATOM   694   N ND2 . ASN A 1 102 ? -48.800 -27.968 71.731 1.00 56.21  ? 304 ASN A ND2 1 
ATOM   695   N N   . ASN A 1 103 ? -47.394 -22.898 70.084 1.00 50.66  ? 305 ASN A N   1 
ATOM   696   C CA  . ASN A 1 103 ? -46.529 -21.730 70.176 1.00 50.51  ? 305 ASN A CA  1 
ATOM   697   C C   . ASN A 1 103 ? -46.828 -20.741 69.063 1.00 50.55  ? 305 ASN A C   1 
ATOM   698   O O   . ASN A 1 103 ? -47.050 -21.130 67.914 1.00 50.76  ? 305 ASN A O   1 
ATOM   699   C CB  . ASN A 1 103 ? -45.051 -22.127 70.114 1.00 50.18  ? 305 ASN A CB  1 
ATOM   700   C CG  . ASN A 1 103 ? -44.599 -22.877 71.345 1.00 50.96  ? 305 ASN A CG  1 
ATOM   701   O OD1 . ASN A 1 103 ? -44.392 -22.286 72.403 1.00 53.71  ? 305 ASN A OD1 1 
ATOM   702   N ND2 . ASN A 1 103 ? -44.434 -24.186 71.212 1.00 51.36  ? 305 ASN A ND2 1 
ATOM   703   N N   . TRP A 1 104 ? -46.824 -19.455 69.416 1.00 47.81  ? 306 TRP A N   1 
ATOM   704   C CA  . TRP A 1 104 ? -46.925 -18.389 68.430 1.00 48.30  ? 306 TRP A CA  1 
ATOM   705   C C   . TRP A 1 104 ? -45.613 -18.120 67.712 1.00 48.20  ? 306 TRP A C   1 
ATOM   706   O O   . TRP A 1 104 ? -45.632 -17.744 66.536 1.00 49.31  ? 306 TRP A O   1 
ATOM   707   C CB  . TRP A 1 104 ? -47.406 -17.098 69.093 1.00 43.98  ? 306 TRP A CB  1 
ATOM   708   C CG  . TRP A 1 104 ? -48.859 -17.082 69.428 1.00 47.00  ? 306 TRP A CG  1 
ATOM   709   C CD1 . TRP A 1 104 ? -49.800 -17.979 69.031 1.00 48.20  ? 306 TRP A CD1 1 
ATOM   710   C CD2 . TRP A 1 104 ? -49.536 -16.127 70.252 1.00 49.33  ? 306 TRP A CD2 1 
ATOM   711   N NE1 . TRP A 1 104 ? -51.027 -17.636 69.541 1.00 49.15  ? 306 TRP A NE1 1 
ATOM   712   C CE2 . TRP A 1 104 ? -50.890 -16.503 70.298 1.00 49.88  ? 306 TRP A CE2 1 
ATOM   713   C CE3 . TRP A 1 104 ? -49.129 -14.988 70.951 1.00 48.70  ? 306 TRP A CE3 1 
ATOM   714   C CZ2 . TRP A 1 104 ? -51.840 -15.783 71.017 1.00 50.36  ? 306 TRP A CZ2 1 
ATOM   715   C CZ3 . TRP A 1 104 ? -50.072 -14.274 71.662 1.00 48.95  ? 306 TRP A CZ3 1 
ATOM   716   C CH2 . TRP A 1 104 ? -51.412 -14.674 71.690 1.00 50.53  ? 306 TRP A CH2 1 
ATOM   717   N N   . GLY A 1 105 ? -44.481 -18.296 68.381 1.00 47.61  ? 307 GLY A N   1 
ATOM   718   C CA  . GLY A 1 105 ? -43.215 -17.966 67.756 1.00 47.49  ? 307 GLY A CA  1 
ATOM   719   C C   . GLY A 1 105 ? -42.061 -18.662 68.437 1.00 47.16  ? 307 GLY A C   1 
ATOM   720   O O   . GLY A 1 105 ? -42.167 -19.132 69.573 1.00 46.36  ? 307 GLY A O   1 
ATOM   721   N N   . PHE A 1 106 ? -40.945 -18.713 67.715 1.00 44.80  ? 308 PHE A N   1 
ATOM   722   C CA  . PHE A 1 106 ? -39.735 -19.361 68.197 1.00 45.75  ? 308 PHE A CA  1 
ATOM   723   C C   . PHE A 1 106 ? -38.541 -18.750 67.479 1.00 46.02  ? 308 PHE A C   1 
ATOM   724   O O   . PHE A 1 106 ? -38.690 -18.039 66.482 1.00 46.12  ? 308 PHE A O   1 
ATOM   725   C CB  . PHE A 1 106 ? -39.787 -20.879 67.998 1.00 42.17  ? 308 PHE A CB  1 
ATOM   726   C CG  . PHE A 1 106 ? -39.873 -21.306 66.563 1.00 43.37  ? 308 PHE A CG  1 
ATOM   727   C CD1 . PHE A 1 106 ? -38.728 -21.580 65.839 1.00 43.80  ? 308 PHE A CD1 1 
ATOM   728   C CD2 . PHE A 1 106 ? -41.098 -21.437 65.939 1.00 45.14  ? 308 PHE A CD2 1 
ATOM   729   C CE1 . PHE A 1 106 ? -38.804 -21.979 64.523 1.00 45.13  ? 308 PHE A CE1 1 
ATOM   730   C CE2 . PHE A 1 106 ? -41.179 -21.833 64.622 1.00 45.85  ? 308 PHE A CE2 1 
ATOM   731   C CZ  . PHE A 1 106 ? -40.030 -22.103 63.913 1.00 44.86  ? 308 PHE A CZ  1 
ATOM   732   N N   . ARG A 1 107 ? -37.346 -19.053 67.991 1.00 46.23  ? 309 ARG A N   1 
ATOM   733   C CA  . ARG A 1 107 ? -36.095 -18.532 67.452 1.00 46.52  ? 309 ARG A CA  1 
ATOM   734   C C   . ARG A 1 107 ? -34.911 -19.186 68.153 1.00 45.92  ? 309 ARG A C   1 
ATOM   735   O O   . ARG A 1 107 ? -34.993 -19.511 69.344 1.00 46.48  ? 309 ARG A O   1 
ATOM   736   C CB  . ARG A 1 107 ? -36.023 -17.014 67.617 1.00 41.28  ? 309 ARG A CB  1 
ATOM   737   C CG  . ARG A 1 107 ? -36.073 -16.558 69.057 1.00 42.76  ? 309 ARG A CG  1 
ATOM   738   C CD  . ARG A 1 107 ? -35.936 -15.058 69.173 1.00 46.09  ? 309 ARG A CD  1 
ATOM   739   N NE  . ARG A 1 107 ? -35.935 -14.626 70.565 1.00 50.82  ? 309 ARG A NE  1 
ATOM   740   C CZ  . ARG A 1 107 ? -35.911 -13.356 70.952 1.00 53.37  ? 309 ARG A CZ  1 
ATOM   741   N NH1 . ARG A 1 107 ? -35.893 -12.388 70.048 1.00 54.67  ? 309 ARG A NH1 1 
ATOM   742   N NH2 . ARG A 1 107 ? -35.914 -13.055 72.242 1.00 54.47  ? 309 ARG A NH2 1 
ATOM   743   N N   . PRO A 1 108 ? -33.801 -19.400 67.453 1.00 42.74  ? 310 PRO A N   1 
ATOM   744   C CA  . PRO A 1 108 ? -32.661 -20.091 68.059 1.00 42.73  ? 310 PRO A CA  1 
ATOM   745   C C   . PRO A 1 108 ? -31.894 -19.208 69.029 1.00 44.15  ? 310 PRO A C   1 
ATOM   746   O O   . PRO A 1 108 ? -31.875 -17.980 68.920 1.00 43.45  ? 310 PRO A O   1 
ATOM   747   C CB  . PRO A 1 108 ? -31.798 -20.463 66.848 1.00 41.77  ? 310 PRO A CB  1 
ATOM   748   C CG  . PRO A 1 108 ? -32.127 -19.430 65.836 1.00 40.31  ? 310 PRO A CG  1 
ATOM   749   C CD  . PRO A 1 108 ? -33.570 -19.097 66.030 1.00 40.51  ? 310 PRO A CD  1 
ATOM   750   N N   . LYS A 1 109 ? -31.234 -19.848 69.988 1.00 44.94  ? 311 LYS A N   1 
ATOM   751   C CA  . LYS A 1 109 ? -30.475 -19.137 71.010 1.00 47.26  ? 311 LYS A CA  1 
ATOM   752   C C   . LYS A 1 109 ? -28.999 -19.523 71.096 1.00 47.14  ? 311 LYS A C   1 
ATOM   753   O O   . LYS A 1 109 ? -28.122 -18.667 70.996 1.00 47.01  ? 311 LYS A O   1 
ATOM   754   C CB  . LYS A 1 109 ? -31.118 -19.359 72.379 1.00 41.68  ? 311 LYS A CB  1 
ATOM   755   C CG  . LYS A 1 109 ? -32.582 -18.972 72.455 1.00 48.51  ? 311 LYS A CG  1 
ATOM   756   C CD  . LYS A 1 109 ? -32.760 -17.467 72.399 1.00 55.64  ? 311 LYS A CD  1 
ATOM   757   C CE  . LYS A 1 109 ? -31.938 -16.781 73.472 1.00 61.13  ? 311 LYS A CE  1 
ATOM   758   N NZ  . LYS A 1 109 ? -32.190 -15.316 73.507 1.00 59.09  ? 311 LYS A NZ  1 
ATOM   759   N N   . ARG A 1 110 ? -28.734 -20.812 71.292 1.00 47.43  ? 312 ARG A N   1 
ATOM   760   C CA  . ARG A 1 110 ? -27.372 -21.314 71.443 1.00 48.59  ? 312 ARG A CA  1 
ATOM   761   C C   . ARG A 1 110 ? -27.087 -22.468 70.502 1.00 47.42  ? 312 ARG A C   1 
ATOM   762   O O   . ARG A 1 110 ? -28.001 -23.124 70.019 1.00 47.16  ? 312 ARG A O   1 
ATOM   763   C CB  . ARG A 1 110 ? -27.112 -21.772 72.878 1.00 46.54  ? 312 ARG A CB  1 
ATOM   764   C CG  . ARG A 1 110 ? -27.961 -21.085 73.928 1.00 55.94  ? 312 ARG A CG  1 
ATOM   765   C CD  . ARG A 1 110 ? -27.169 -20.852 75.198 1.00 64.86  ? 312 ARG A CD  1 
ATOM   766   N NE  . ARG A 1 110 ? -25.963 -20.075 74.933 1.00 74.64  ? 312 ARG A NE  1 
ATOM   767   C CZ  . ARG A 1 110 ? -25.355 -19.308 75.831 1.00 79.60  ? 312 ARG A CZ  1 
ATOM   768   N NH1 . ARG A 1 110 ? -25.844 -19.204 77.060 1.00 81.58  ? 312 ARG A NH1 1 
ATOM   769   N NH2 . ARG A 1 110 ? -24.261 -18.638 75.499 1.00 80.76  ? 312 ARG A NH2 1 
ATOM   770   N N   . LEU A 1 111 ? -25.808 -22.708 70.247 1.00 43.90  ? 313 LEU A N   1 
ATOM   771   C CA  . LEU A 1 111 ? -25.387 -23.764 69.344 1.00 42.63  ? 313 LEU A CA  1 
ATOM   772   C C   . LEU A 1 111 ? -24.212 -24.536 69.919 1.00 42.92  ? 313 LEU A C   1 
ATOM   773   O O   . LEU A 1 111 ? -23.262 -23.939 70.406 1.00 42.33  ? 313 LEU A O   1 
ATOM   774   C CB  . LEU A 1 111 ? -24.957 -23.119 68.026 1.00 38.51  ? 313 LEU A CB  1 
ATOM   775   C CG  . LEU A 1 111 ? -24.872 -23.868 66.700 1.00 38.44  ? 313 LEU A CG  1 
ATOM   776   C CD1 . LEU A 1 111 ? -23.959 -25.076 66.760 1.00 39.72  ? 313 LEU A CD1 1 
ATOM   777   C CD2 . LEU A 1 111 ? -26.252 -24.223 66.181 1.00 43.64  ? 313 LEU A CD2 1 
ATOM   778   N N   . ASN A 1 112 ? -24.285 -25.862 69.894 1.00 44.85  ? 314 ASN A N   1 
ATOM   779   C CA  . ASN A 1 112 ? -23.177 -26.690 70.345 1.00 45.40  ? 314 ASN A CA  1 
ATOM   780   C C   . ASN A 1 112 ? -22.935 -27.760 69.294 1.00 44.01  ? 314 ASN A C   1 
ATOM   781   O O   . ASN A 1 112 ? -23.843 -28.527 68.965 1.00 45.69  ? 314 ASN A O   1 
ATOM   782   C CB  . ASN A 1 112 ? -23.471 -27.325 71.709 1.00 45.25  ? 314 ASN A CB  1 
ATOM   783   C CG  . ASN A 1 112 ? -22.250 -27.977 72.327 1.00 51.42  ? 314 ASN A CG  1 
ATOM   784   O OD1 . ASN A 1 112 ? -21.281 -28.294 71.639 1.00 54.43  ? 314 ASN A OD1 1 
ATOM   785   N ND2 . ASN A 1 112 ? -22.292 -28.182 73.636 1.00 55.49  ? 314 ASN A ND2 1 
ATOM   786   N N   . PHE A 1 113 ? -21.713 -27.807 68.775 1.00 41.56  ? 315 PHE A N   1 
ATOM   787   C CA  . PHE A 1 113 ? -21.345 -28.712 67.698 1.00 40.13  ? 315 PHE A CA  1 
ATOM   788   C C   . PHE A 1 113 ? -20.315 -29.695 68.225 1.00 40.47  ? 315 PHE A C   1 
ATOM   789   O O   . PHE A 1 113 ? -19.478 -29.328 69.052 1.00 40.48  ? 315 PHE A O   1 
ATOM   790   C CB  . PHE A 1 113 ? -20.786 -27.927 66.509 1.00 38.31  ? 315 PHE A CB  1 
ATOM   791   C CG  . PHE A 1 113 ? -20.347 -28.783 65.362 1.00 37.71  ? 315 PHE A CG  1 
ATOM   792   C CD1 . PHE A 1 113 ? -21.265 -29.257 64.448 1.00 38.26  ? 315 PHE A CD1 1 
ATOM   793   C CD2 . PHE A 1 113 ? -19.012 -29.100 65.187 1.00 37.30  ? 315 PHE A CD2 1 
ATOM   794   C CE1 . PHE A 1 113 ? -20.862 -30.036 63.386 1.00 38.26  ? 315 PHE A CE1 1 
ATOM   795   C CE2 . PHE A 1 113 ? -18.604 -29.877 64.127 1.00 36.38  ? 315 PHE A CE2 1 
ATOM   796   C CZ  . PHE A 1 113 ? -19.530 -30.348 63.227 1.00 37.85  ? 315 PHE A CZ  1 
ATOM   797   N N   . LYS A 1 114 ? -20.381 -30.939 67.760 1.00 42.17  ? 316 LYS A N   1 
ATOM   798   C CA  . LYS A 1 114 ? -19.412 -31.954 68.143 1.00 42.99  ? 316 LYS A CA  1 
ATOM   799   C C   . LYS A 1 114 ? -19.073 -32.835 66.952 1.00 42.66  ? 316 LYS A C   1 
ATOM   800   O O   . LYS A 1 114 ? -19.940 -33.200 66.155 1.00 44.08  ? 316 LYS A O   1 
ATOM   801   C CB  . LYS A 1 114 ? -19.908 -32.833 69.302 1.00 41.99  ? 316 LYS A CB  1 
ATOM   802   C CG  . LYS A 1 114 ? -19.985 -32.119 70.639 1.00 44.20  ? 316 LYS A CG  1 
ATOM   803   C CD  . LYS A 1 114 ? -20.531 -33.025 71.722 1.00 46.99  ? 316 LYS A CD  1 
ATOM   804   C CE  . LYS A 1 114 ? -20.583 -32.306 73.058 1.00 48.86  ? 316 LYS A CE  1 
ATOM   805   N NZ  . LYS A 1 114 ? -21.193 -33.147 74.123 1.00 52.90  ? 316 LYS A NZ  1 
ATOM   806   N N   . LEU A 1 115 ? -17.791 -33.166 66.851 1.00 43.25  ? 317 LEU A N   1 
ATOM   807   C CA  . LEU A 1 115 ? -17.266 -34.074 65.841 1.00 42.61  ? 317 LEU A CA  1 
ATOM   808   C C   . LEU A 1 115 ? -16.384 -35.074 66.565 1.00 42.89  ? 317 LEU A C   1 
ATOM   809   O O   . LEU A 1 115 ? -15.375 -34.686 67.160 1.00 43.56  ? 317 LEU A O   1 
ATOM   810   C CB  . LEU A 1 115 ? -16.470 -33.304 64.786 1.00 40.59  ? 317 LEU A CB  1 
ATOM   811   C CG  . LEU A 1 115 ? -15.729 -34.087 63.709 1.00 43.69  ? 317 LEU A CG  1 
ATOM   812   C CD1 . LEU A 1 115 ? -16.707 -34.836 62.847 1.00 44.50  ? 317 LEU A CD1 1 
ATOM   813   C CD2 . LEU A 1 115 ? -14.881 -33.152 62.875 1.00 44.79  ? 317 LEU A CD2 1 
ATOM   814   N N   . PHE A 1 116 ? -16.756 -36.350 66.533 1.00 48.02  ? 318 PHE A N   1 
ATOM   815   C CA  . PHE A 1 116 ? -16.076 -37.322 67.378 1.00 48.57  ? 318 PHE A CA  1 
ATOM   816   C C   . PHE A 1 116 ? -16.123 -38.695 66.723 1.00 49.66  ? 318 PHE A C   1 
ATOM   817   O O   . PHE A 1 116 ? -16.715 -38.880 65.658 1.00 50.95  ? 318 PHE A O   1 
ATOM   818   C CB  . PHE A 1 116 ? -16.695 -37.352 68.779 1.00 49.81  ? 318 PHE A CB  1 
ATOM   819   C CG  . PHE A 1 116 ? -18.159 -37.677 68.790 1.00 50.72  ? 318 PHE A CG  1 
ATOM   820   C CD1 . PHE A 1 116 ? -18.595 -38.980 68.934 1.00 50.65  ? 318 PHE A CD1 1 
ATOM   821   C CD2 . PHE A 1 116 ? -19.102 -36.677 68.642 1.00 50.90  ? 318 PHE A CD2 1 
ATOM   822   C CE1 . PHE A 1 116 ? -19.941 -39.276 68.950 1.00 50.02  ? 318 PHE A CE1 1 
ATOM   823   C CE2 . PHE A 1 116 ? -20.447 -36.967 68.648 1.00 51.12  ? 318 PHE A CE2 1 
ATOM   824   C CZ  . PHE A 1 116 ? -20.867 -38.268 68.801 1.00 51.42  ? 318 PHE A CZ  1 
ATOM   825   N N   . ASN A 1 117 ? -15.488 -39.657 67.394 1.00 51.02  ? 319 ASN A N   1 
ATOM   826   C CA  . ASN A 1 117 ? -15.364 -41.033 66.915 1.00 51.44  ? 319 ASN A CA  1 
ATOM   827   C C   . ASN A 1 117 ? -14.817 -41.074 65.492 1.00 51.95  ? 319 ASN A C   1 
ATOM   828   O O   . ASN A 1 117 ? -15.379 -41.706 64.597 1.00 54.04  ? 319 ASN A O   1 
ATOM   829   C CB  . ASN A 1 117 ? -16.697 -41.774 67.014 1.00 50.76  ? 319 ASN A CB  1 
ATOM   830   C CG  . ASN A 1 117 ? -17.077 -42.094 68.442 1.00 53.27  ? 319 ASN A CG  1 
ATOM   831   O OD1 . ASN A 1 117 ? -16.224 -42.147 69.324 1.00 52.45  ? 319 ASN A OD1 1 
ATOM   832   N ND2 . ASN A 1 117 ? -18.361 -42.327 68.674 1.00 54.76  ? 319 ASN A ND2 1 
ATOM   833   N N   . ILE A 1 118 ? -13.691 -40.393 65.289 1.00 52.32  ? 320 ILE A N   1 
ATOM   834   C CA  . ILE A 1 118 ? -13.096 -40.319 63.963 1.00 52.73  ? 320 ILE A CA  1 
ATOM   835   C C   . ILE A 1 118 ? -12.433 -41.645 63.622 1.00 53.73  ? 320 ILE A C   1 
ATOM   836   O O   . ILE A 1 118 ? -11.624 -42.177 64.393 1.00 54.84  ? 320 ILE A O   1 
ATOM   837   C CB  . ILE A 1 118 ? -12.094 -39.155 63.887 1.00 48.82  ? 320 ILE A CB  1 
ATOM   838   C CG1 . ILE A 1 118 ? -12.789 -37.842 64.240 1.00 48.21  ? 320 ILE A CG1 1 
ATOM   839   C CG2 . ILE A 1 118 ? -11.486 -39.065 62.502 1.00 49.20  ? 320 ILE A CG2 1 
ATOM   840   C CD1 . ILE A 1 118 ? -13.954 -37.514 63.337 1.00 50.70  ? 320 ILE A CD1 1 
ATOM   841   N N   . GLN A 1 119 ? -12.783 -42.191 62.461 1.00 51.89  ? 321 GLN A N   1 
ATOM   842   C CA  . GLN A 1 119 ? -12.196 -43.429 61.967 1.00 53.03  ? 321 GLN A CA  1 
ATOM   843   C C   . GLN A 1 119 ? -11.704 -43.182 60.553 1.00 53.26  ? 321 GLN A C   1 
ATOM   844   O O   . GLN A 1 119 ? -12.495 -42.816 59.679 1.00 54.09  ? 321 GLN A O   1 
ATOM   845   C CB  . GLN A 1 119 ? -13.213 -44.572 61.987 1.00 54.36  ? 321 GLN A CB  1 
ATOM   846   C CG  . GLN A 1 119 ? -13.677 -44.969 63.372 1.00 56.65  ? 321 GLN A CG  1 
ATOM   847   C CD  . GLN A 1 119 ? -14.762 -46.021 63.336 1.00 58.96  ? 321 GLN A CD  1 
ATOM   848   O OE1 . GLN A 1 119 ? -15.476 -46.156 62.343 1.00 57.95  ? 321 GLN A OE1 1 
ATOM   849   N NE2 . GLN A 1 119 ? -14.900 -46.768 64.423 1.00 58.11  ? 321 GLN A NE2 1 
ATOM   850   N N   . VAL A 1 120 ? -10.407 -43.368 60.329 1.00 51.72  ? 322 VAL A N   1 
ATOM   851   C CA  . VAL A 1 120 ? -9.795  -43.189 59.019 1.00 52.20  ? 322 VAL A CA  1 
ATOM   852   C C   . VAL A 1 120 ? -9.682  -44.551 58.355 1.00 52.84  ? 322 VAL A C   1 
ATOM   853   O O   . VAL A 1 120 ? -9.211  -45.512 58.972 1.00 53.05  ? 322 VAL A O   1 
ATOM   854   C CB  . VAL A 1 120 ? -8.418  -42.513 59.120 1.00 51.75  ? 322 VAL A CB  1 
ATOM   855   C CG1 . VAL A 1 120 ? -7.767  -42.463 57.757 1.00 51.54  ? 322 VAL A CG1 1 
ATOM   856   C CG2 . VAL A 1 120 ? -8.551  -41.116 59.699 1.00 50.01  ? 322 VAL A CG2 1 
ATOM   857   N N   . LYS A 1 121 ? -10.117 -44.634 57.102 1.00 52.40  ? 323 LYS A N   1 
ATOM   858   C CA  . LYS A 1 121 ? -10.086 -45.868 56.335 1.00 54.26  ? 323 LYS A CA  1 
ATOM   859   C C   . LYS A 1 121 ? -9.241  -45.668 55.086 1.00 55.87  ? 323 LYS A C   1 
ATOM   860   O O   . LYS A 1 121 ? -9.504  -44.763 54.289 1.00 56.02  ? 323 LYS A O   1 
ATOM   861   C CB  . LYS A 1 121 ? -11.497 -46.306 55.932 1.00 52.56  ? 323 LYS A CB  1 
ATOM   862   C CG  . LYS A 1 121 ? -12.469 -46.490 57.086 1.00 53.78  ? 323 LYS A CG  1 
ATOM   863   C CD  . LYS A 1 121 ? -12.010 -47.577 58.033 1.00 55.77  ? 323 LYS A CD  1 
ATOM   864   C CE  . LYS A 1 121 ? -13.030 -47.810 59.130 1.00 56.60  ? 323 LYS A CE  1 
ATOM   865   N NZ  . LYS A 1 121 ? -12.578 -48.851 60.091 1.00 58.37  ? 323 LYS A NZ  1 
ATOM   866   N N   . GLU A 1 122 ? -8.228  -46.511 54.918 1.00 58.30  ? 324 GLU A N   1 
ATOM   867   C CA  . GLU A 1 122 ? -7.414  -46.519 53.713 1.00 62.42  ? 324 GLU A CA  1 
ATOM   868   C C   . GLU A 1 122 ? -7.860  -47.660 52.812 1.00 62.48  ? 324 GLU A C   1 
ATOM   869   O O   . GLU A 1 122 ? -8.227  -48.736 53.294 1.00 62.76  ? 324 GLU A O   1 
ATOM   870   C CB  . GLU A 1 122 ? -5.924  -46.652 54.040 1.00 57.77  ? 324 GLU A CB  1 
ATOM   871   C CG  . GLU A 1 122 ? -5.537  -47.942 54.741 1.00 68.37  ? 324 GLU A CG  1 
ATOM   872   C CD  . GLU A 1 122 ? -4.061  -47.991 55.091 1.00 75.05  ? 324 GLU A CD  1 
ATOM   873   O OE1 . GLU A 1 122 ? -3.285  -47.206 54.507 1.00 78.25  ? 324 GLU A OE1 1 
ATOM   874   O OE2 . GLU A 1 122 ? -3.678  -48.815 55.949 1.00 77.52  ? 324 GLU A OE2 1 
ATOM   875   N N   . VAL A 1 123 ? -7.845  -47.418 51.505 1.00 64.79  ? 325 VAL A N   1 
ATOM   876   C CA  . VAL A 1 123 ? -8.315  -48.412 50.548 1.00 66.46  ? 325 VAL A CA  1 
ATOM   877   C C   . VAL A 1 123 ? -7.151  -48.906 49.702 1.00 68.91  ? 325 VAL A C   1 
ATOM   878   O O   . VAL A 1 123 ? -6.627  -48.174 48.856 1.00 68.49  ? 325 VAL A O   1 
ATOM   879   C CB  . VAL A 1 123 ? -9.433  -47.839 49.658 1.00 65.30  ? 325 VAL A CB  1 
ATOM   880   C CG1 . VAL A 1 123 ? -9.847  -48.855 48.613 1.00 64.14  ? 325 VAL A CG1 1 
ATOM   881   C CG2 . VAL A 1 123 ? -10.620 -47.427 50.504 1.00 64.63  ? 325 VAL A CG2 1 
ATOM   882   N N   . THR A 1 124 ? -6.743  -50.153 49.919 1.00 72.02  ? 326 THR A N   1 
ATOM   883   C CA  . THR A 1 124 ? -5.705  -50.749 49.091 1.00 76.35  ? 326 THR A CA  1 
ATOM   884   C C   . THR A 1 124 ? -6.344  -51.511 47.939 1.00 79.55  ? 326 THR A C   1 
ATOM   885   O O   . THR A 1 124 ? -7.284  -52.286 48.135 1.00 79.45  ? 326 THR A O   1 
ATOM   886   C CB  . THR A 1 124 ? -4.823  -51.677 49.927 1.00 77.86  ? 326 THR A CB  1 
ATOM   887   O OG1 . THR A 1 124 ? -5.627  -52.706 50.514 1.00 79.67  ? 326 THR A OG1 1 
ATOM   888   C CG2 . THR A 1 124 ? -4.130  -50.896 51.033 1.00 77.25  ? 326 THR A CG2 1 
ATOM   889   N N   . ASP A 1 125 ? -5.836  -51.282 46.732 1.00 85.22  ? 327 ASP A N   1 
ATOM   890   C CA  . ASP A 1 125 ? -6.445  -51.813 45.521 1.00 89.91  ? 327 ASP A CA  1 
ATOM   891   C C   . ASP A 1 125 ? -5.474  -52.755 44.828 1.00 91.44  ? 327 ASP A C   1 
ATOM   892   O O   . ASP A 1 125 ? -4.295  -52.428 44.658 1.00 91.36  ? 327 ASP A O   1 
ATOM   893   C CB  . ASP A 1 125 ? -6.853  -50.682 44.570 1.00 89.78  ? 327 ASP A CB  1 
ATOM   894   C CG  . ASP A 1 125 ? -7.605  -51.183 43.352 1.00 93.83  ? 327 ASP A CG  1 
ATOM   895   O OD1 . ASP A 1 125 ? -7.893  -52.395 43.274 1.00 95.61  ? 327 ASP A OD1 1 
ATOM   896   O OD2 . ASP A 1 125 ? -7.911  -50.359 42.466 1.00 95.86  ? 327 ASP A OD2 1 
ATOM   897   N N   . ASN A 1 126 ? -5.973  -53.923 44.435 1.00 96.10  ? 328 ASN A N   1 
ATOM   898   C CA  . ASN A 1 126 ? -5.242  -54.854 43.588 1.00 98.89  ? 328 ASN A CA  1 
ATOM   899   C C   . ASN A 1 126 ? -6.182  -55.328 42.492 1.00 100.10 ? 328 ASN A C   1 
ATOM   900   O O   . ASN A 1 126 ? -7.176  -56.003 42.776 1.00 99.97  ? 328 ASN A O   1 
ATOM   901   C CB  . ASN A 1 126 ? -4.712  -56.045 44.395 1.00 99.82  ? 328 ASN A CB  1 
ATOM   902   C CG  . ASN A 1 126 ? -3.781  -56.936 43.588 1.00 101.78 ? 328 ASN A CG  1 
ATOM   903   O OD1 . ASN A 1 126 ? -3.758  -56.889 42.358 1.00 102.14 ? 328 ASN A OD1 1 
ATOM   904   N ND2 . ASN A 1 126 ? -3.014  -57.766 44.286 1.00 102.33 ? 328 ASN A ND2 1 
ATOM   905   N N   . ASN A 1 127 ? -5.859  -54.985 41.246 1.00 100.13 ? 329 ASN A N   1 
ATOM   906   C CA  . ASN A 1 127 ? -6.665  -55.349 40.073 1.00 101.48 ? 329 ASN A CA  1 
ATOM   907   C C   . ASN A 1 127 ? -8.092  -54.853 40.316 1.00 100.94 ? 329 ASN A C   1 
ATOM   908   O O   . ASN A 1 127 ? -8.293  -53.640 40.468 1.00 101.31 ? 329 ASN A O   1 
ATOM   909   C CB  . ASN A 1 127 ? -6.526  -56.841 39.804 1.00 99.92  ? 329 ASN A CB  1 
ATOM   910   C CG  . ASN A 1 127 ? -5.111  -57.238 39.446 1.00 102.37 ? 329 ASN A CG  1 
ATOM   911   O OD1 . ASN A 1 127 ? -4.566  -58.200 39.989 1.00 103.53 ? 329 ASN A OD1 1 
ATOM   912   N ND2 . ASN A 1 127 ? -4.504  -56.496 38.528 1.00 102.46 ? 329 ASN A ND2 1 
ATOM   913   N N   . GLY A 1 128 ? -9.090  -55.730 40.363 1.00 99.95  ? 330 GLY A N   1 
ATOM   914   C CA  . GLY A 1 128 ? -10.463 -55.341 40.589 1.00 98.17  ? 330 GLY A CA  1 
ATOM   915   C C   . GLY A 1 128 ? -10.999 -55.602 41.977 1.00 96.85  ? 330 GLY A C   1 
ATOM   916   O O   . GLY A 1 128 ? -12.184 -55.358 42.224 1.00 97.27  ? 330 GLY A O   1 
ATOM   917   N N   . VAL A 1 129 ? -10.172 -56.095 42.895 1.00 97.24  ? 331 VAL A N   1 
ATOM   918   C CA  . VAL A 1 129 ? -10.579 -56.359 44.271 1.00 93.71  ? 331 VAL A CA  1 
ATOM   919   C C   . VAL A 1 129 ? -9.897  -55.342 45.178 1.00 91.64  ? 331 VAL A C   1 
ATOM   920   O O   . VAL A 1 129 ? -8.684  -55.118 45.074 1.00 91.29  ? 331 VAL A O   1 
ATOM   921   C CB  . VAL A 1 129 ? -10.256 -57.807 44.689 1.00 92.01  ? 331 VAL A CB  1 
ATOM   922   C CG1 . VAL A 1 129 ? -8.764  -58.100 44.580 1.00 90.73  ? 331 VAL A CG1 1 
ATOM   923   C CG2 . VAL A 1 129 ? -10.756 -58.077 46.099 1.00 91.63  ? 331 VAL A CG2 1 
ATOM   924   N N   . LYS A 1 130 ? -10.677 -54.711 46.050 1.00 86.31  ? 332 LYS A N   1 
ATOM   925   C CA  . LYS A 1 130 ? -10.181 -53.659 46.927 1.00 82.83  ? 332 LYS A CA  1 
ATOM   926   C C   . LYS A 1 130 ? -10.307 -54.091 48.380 1.00 80.19  ? 332 LYS A C   1 
ATOM   927   O O   . LYS A 1 130 ? -11.285 -54.744 48.759 1.00 80.48  ? 332 LYS A O   1 
ATOM   928   C CB  . LYS A 1 130 ? -10.932 -52.344 46.695 1.00 79.88  ? 332 LYS A CB  1 
ATOM   929   C CG  . LYS A 1 130 ? -12.420 -52.394 46.990 1.00 80.35  ? 332 LYS A CG  1 
ATOM   930   C CD  . LYS A 1 130 ? -13.061 -51.037 46.749 1.00 80.79  ? 332 LYS A CD  1 
ATOM   931   C CE  . LYS A 1 130 ? -13.022 -50.669 45.276 1.00 81.61  ? 332 LYS A CE  1 
ATOM   932   N NZ  . LYS A 1 130 ? -13.640 -49.340 45.013 1.00 81.23  ? 332 LYS A NZ  1 
ATOM   933   N N   . THR A 1 131 ? -9.316  -53.722 49.185 1.00 79.74  ? 333 THR A N   1 
ATOM   934   C CA  . THR A 1 131 ? -9.284  -54.026 50.608 1.00 76.75  ? 333 THR A CA  1 
ATOM   935   C C   . THR A 1 131 ? -9.334  -52.724 51.391 1.00 73.70  ? 333 THR A C   1 
ATOM   936   O O   . THR A 1 131 ? -8.570  -51.796 51.108 1.00 73.66  ? 333 THR A O   1 
ATOM   937   C CB  . THR A 1 131 ? -8.025  -54.814 50.972 1.00 77.81  ? 333 THR A CB  1 
ATOM   938   O OG1 . THR A 1 131 ? -8.010  -56.056 50.258 1.00 78.62  ? 333 THR A OG1 1 
ATOM   939   C CG2 . THR A 1 131 ? -7.980  -55.089 52.467 1.00 77.97  ? 333 THR A CG2 1 
ATOM   940   N N   . ILE A 1 132 ? -10.227 -52.659 52.371 1.00 71.21  ? 334 ILE A N   1 
ATOM   941   C CA  . ILE A 1 132 ? -10.440 -51.459 53.168 1.00 67.01  ? 334 ILE A CA  1 
ATOM   942   C C   . ILE A 1 132 ? -9.930  -51.747 54.573 1.00 65.44  ? 334 ILE A C   1 
ATOM   943   O O   . ILE A 1 132 ? -10.421 -52.660 55.247 1.00 65.46  ? 334 ILE A O   1 
ATOM   944   C CB  . ILE A 1 132 ? -11.915 -51.043 53.181 1.00 62.61  ? 334 ILE A CB  1 
ATOM   945   C CG1 . ILE A 1 132 ? -12.368 -50.681 51.767 1.00 61.46  ? 334 ILE A CG1 1 
ATOM   946   C CG2 . ILE A 1 132 ? -12.128 -49.874 54.119 1.00 62.10  ? 334 ILE A CG2 1 
ATOM   947   C CD1 . ILE A 1 132 ? -13.858 -50.497 51.634 1.00 62.39  ? 334 ILE A CD1 1 
ATOM   948   N N   . ALA A 1 133 ? -8.945  -50.973 55.018 1.00 63.97  ? 335 ALA A N   1 
ATOM   949   C CA  . ALA A 1 133 ? -8.303  -51.192 56.302 1.00 63.18  ? 335 ALA A CA  1 
ATOM   950   C C   . ALA A 1 133 ? -8.200  -49.885 57.074 1.00 63.63  ? 335 ALA A C   1 
ATOM   951   O O   . ALA A 1 133 ? -8.408  -48.798 56.530 1.00 65.27  ? 335 ALA A O   1 
ATOM   952   C CB  . ALA A 1 133 ? -6.908  -51.804 56.129 1.00 64.63  ? 335 ALA A CB  1 
ATOM   953   N N   . ASN A 1 134 ? -7.877  -50.008 58.358 1.00 61.98  ? 336 ASN A N   1 
ATOM   954   C CA  . ASN A 1 134 ? -7.717  -48.839 59.209 1.00 62.75  ? 336 ASN A CA  1 
ATOM   955   C C   . ASN A 1 134 ? -6.334  -48.229 59.039 1.00 62.69  ? 336 ASN A C   1 
ATOM   956   O O   . ASN A 1 134 ? -5.345  -48.935 58.826 1.00 62.51  ? 336 ASN A O   1 
ATOM   957   C CB  . ASN A 1 134 ? -7.930  -49.210 60.675 1.00 59.49  ? 336 ASN A CB  1 
ATOM   958   C CG  . ASN A 1 134 ? -9.372  -49.525 60.996 1.00 61.59  ? 336 ASN A CG  1 
ATOM   959   O OD1 . ASN A 1 134 ? -10.285 -49.075 60.306 1.00 64.63  ? 336 ASN A OD1 1 
ATOM   960   N ND2 . ASN A 1 134 ? -9.587  -50.299 62.052 1.00 61.68  ? 336 ASN A ND2 1 
ATOM   961   N N   . ASN A 1 135 ? -6.271  -46.906 59.123 1.00 59.60  ? 337 ASN A N   1 
ATOM   962   C CA  . ASN A 1 135 ? -5.015  -46.180 59.264 1.00 59.50  ? 337 ASN A CA  1 
ATOM   963   C C   . ASN A 1 135 ? -5.123  -45.381 60.555 1.00 58.53  ? 337 ASN A C   1 
ATOM   964   O O   . ASN A 1 135 ? -5.884  -44.411 60.629 1.00 59.49  ? 337 ASN A O   1 
ATOM   965   C CB  . ASN A 1 135 ? -4.766  -45.281 58.057 1.00 58.37  ? 337 ASN A CB  1 
ATOM   966   C CG  . ASN A 1 135 ? -3.375  -44.684 58.047 1.00 62.38  ? 337 ASN A CG  1 
ATOM   967   O OD1 . ASN A 1 135 ? -2.708  -44.606 59.077 1.00 64.09  ? 337 ASN A OD1 1 
ATOM   968   N ND2 . ASN A 1 135 ? -2.927  -44.261 56.872 1.00 66.04  ? 337 ASN A ND2 1 
ATOM   969   N N   . LEU A 1 136 ? -4.395  -45.776 61.588 1.00 57.34  ? 338 LEU A N   1 
ATOM   970   C CA  . LEU A 1 136 ? -4.481  -45.062 62.859 1.00 55.83  ? 338 LEU A CA  1 
ATOM   971   C C   . LEU A 1 136 ? -3.731  -43.734 62.837 1.00 56.34  ? 338 LEU A C   1 
ATOM   972   O O   . LEU A 1 136 ? -4.136  -42.774 63.479 1.00 56.65  ? 338 LEU A O   1 
ATOM   973   C CB  . LEU A 1 136 ? -3.995  -45.944 64.008 1.00 55.84  ? 338 LEU A CB  1 
ATOM   974   C CG  . LEU A 1 136 ? -4.711  -47.291 64.118 1.00 55.01  ? 338 LEU A CG  1 
ATOM   975   C CD1 . LEU A 1 136 ? -4.273  -48.035 65.365 1.00 50.97  ? 338 LEU A CD1 1 
ATOM   976   C CD2 . LEU A 1 136 ? -6.215  -47.090 64.123 1.00 54.21  ? 338 LEU A CD2 1 
ATOM   977   N N   . THR A 1 137 ? -2.633  -43.696 62.097 1.00 55.86  ? 339 THR A N   1 
ATOM   978   C CA  . THR A 1 137 ? -1.803  -42.504 61.961 1.00 55.98  ? 339 THR A CA  1 
ATOM   979   C C   . THR A 1 137 ? -2.481  -41.312 61.281 1.00 55.02  ? 339 THR A C   1 
ATOM   980   O O   . THR A 1 137 ? -2.266  -40.168 61.668 1.00 55.34  ? 339 THR A O   1 
ATOM   981   C CB  . THR A 1 137 ? -0.515  -42.818 61.187 1.00 55.92  ? 339 THR A CB  1 
ATOM   982   O OG1 . THR A 1 137 ? -0.835  -43.058 59.812 1.00 58.19  ? 339 THR A OG1 1 
ATOM   983   C CG2 . THR A 1 137 ? 0.171   -44.037 61.776 1.00 55.85  ? 339 THR A CG2 1 
ATOM   984   N N   . SER A 1 138 ? -3.300  -41.579 60.272 1.00 52.39  ? 340 SER A N   1 
ATOM   985   C CA  . SER A 1 138 ? -3.946  -40.514 59.511 1.00 51.91  ? 340 SER A CA  1 
ATOM   986   C C   . SER A 1 138 ? -4.841  -39.614 60.343 1.00 51.14  ? 340 SER A C   1 
ATOM   987   O O   . SER A 1 138 ? -5.480  -40.050 61.296 1.00 50.67  ? 340 SER A O   1 
ATOM   988   C CB  . SER A 1 138 ? -4.748  -41.095 58.350 1.00 52.57  ? 340 SER A CB  1 
ATOM   989   O OG  . SER A 1 138 ? -3.890  -41.588 57.339 1.00 59.03  ? 340 SER A OG  1 
ATOM   990   N N   . THR A 1 139 ? -4.861  -38.339 59.968 1.00 40.29  ? 341 THR A N   1 
ATOM   991   C CA  . THR A 1 139 ? -5.644  -37.326 60.663 1.00 40.65  ? 341 THR A CA  1 
ATOM   992   C C   . THR A 1 139 ? -6.523  -36.532 59.712 1.00 39.70  ? 341 THR A C   1 
ATOM   993   O O   . THR A 1 139 ? -6.297  -36.515 58.510 1.00 39.37  ? 341 THR A O   1 
ATOM   994   C CB  . THR A 1 139 ? -4.753  -36.355 61.469 1.00 42.22  ? 341 THR A CB  1 
ATOM   995   O OG1 . THR A 1 139 ? -3.641  -35.944 60.673 1.00 42.85  ? 341 THR A OG1 1 
ATOM   996   C CG2 . THR A 1 139 ? -4.233  -37.026 62.724 1.00 45.01  ? 341 THR A CG2 1 
ATOM   997   N N   . VAL A 1 140 ? -7.557  -35.917 60.272 1.00 37.63  ? 342 VAL A N   1 
ATOM   998   C CA  . VAL A 1 140 ? -8.505  -35.107 59.527 1.00 36.73  ? 342 VAL A CA  1 
ATOM   999   C C   . VAL A 1 140 ? -8.423  -33.667 60.012 1.00 36.19  ? 342 VAL A C   1 
ATOM   1000  O O   . VAL A 1 140 ? -8.388  -33.417 61.210 1.00 36.81  ? 342 VAL A O   1 
ATOM   1001  C CB  . VAL A 1 140 ? -9.948  -35.610 59.719 1.00 34.93  ? 342 VAL A CB  1 
ATOM   1002  C CG1 . VAL A 1 140 ? -10.881 -34.921 58.743 1.00 37.58  ? 342 VAL A CG1 1 
ATOM   1003  C CG2 . VAL A 1 140 ? -10.019 -37.109 59.516 1.00 36.35  ? 342 VAL A CG2 1 
ATOM   1004  N N   . GLN A 1 141 ? -8.369  -32.725 59.077 1.00 32.22  ? 343 GLN A N   1 
ATOM   1005  C CA  . GLN A 1 141 ? -8.295  -31.307 59.404 1.00 31.97  ? 343 GLN A CA  1 
ATOM   1006  C C   . GLN A 1 141 ? -9.673  -30.665 59.407 1.00 31.21  ? 343 GLN A C   1 
ATOM   1007  O O   . GLN A 1 141 ? -10.404 -30.751 58.434 1.00 31.95  ? 343 GLN A O   1 
ATOM   1008  C CB  . GLN A 1 141 ? -7.432  -30.578 58.384 1.00 28.63  ? 343 GLN A CB  1 
ATOM   1009  C CG  . GLN A 1 141 ? -5.965  -30.942 58.391 1.00 30.90  ? 343 GLN A CG  1 
ATOM   1010  C CD  . GLN A 1 141 ? -5.302  -30.570 57.087 1.00 34.76  ? 343 GLN A CD  1 
ATOM   1011  O OE1 . GLN A 1 141 ? -5.972  -30.211 56.126 1.00 37.52  ? 343 GLN A OE1 1 
ATOM   1012  N NE2 . GLN A 1 141 ? -3.986  -30.662 57.043 1.00 36.01  ? 343 GLN A NE2 1 
ATOM   1013  N N   . VAL A 1 142 ? -10.007 -29.994 60.498 1.00 32.81  ? 344 VAL A N   1 
ATOM   1014  C CA  . VAL A 1 142 ? -11.296 -29.331 60.650 1.00 32.78  ? 344 VAL A CA  1 
ATOM   1015  C C   . VAL A 1 142 ? -11.076 -27.945 61.241 1.00 33.65  ? 344 VAL A C   1 
ATOM   1016  O O   . VAL A 1 142 ? -10.262 -27.769 62.154 1.00 34.55  ? 344 VAL A O   1 
ATOM   1017  C CB  . VAL A 1 142 ? -12.265 -30.165 61.522 1.00 34.41  ? 344 VAL A CB  1 
ATOM   1018  C CG1 . VAL A 1 142 ? -11.712 -30.364 62.920 1.00 33.64  ? 344 VAL A CG1 1 
ATOM   1019  C CG2 . VAL A 1 142 ? -13.631 -29.506 61.583 1.00 36.98  ? 344 VAL A CG2 1 
ATOM   1020  N N   . PHE A 1 143 ? -11.783 -26.953 60.704 1.00 29.44  ? 345 PHE A N   1 
ATOM   1021  C CA  . PHE A 1 143 ? -11.772 -25.629 61.304 1.00 29.87  ? 345 PHE A CA  1 
ATOM   1022  C C   . PHE A 1 143 ? -13.078 -24.928 60.984 1.00 30.76  ? 345 PHE A C   1 
ATOM   1023  O O   . PHE A 1 143 ? -13.740 -25.222 59.987 1.00 31.23  ? 345 PHE A O   1 
ATOM   1024  C CB  . PHE A 1 143 ? -10.593 -24.772 60.824 1.00 27.07  ? 345 PHE A CB  1 
ATOM   1025  C CG  . PHE A 1 143 ? -10.686 -24.341 59.385 1.00 27.73  ? 345 PHE A CG  1 
ATOM   1026  C CD1 . PHE A 1 143 ? -11.251 -23.122 59.052 1.00 27.11  ? 345 PHE A CD1 1 
ATOM   1027  C CD2 . PHE A 1 143 ? -10.205 -25.144 58.372 1.00 28.59  ? 345 PHE A CD2 1 
ATOM   1028  C CE1 . PHE A 1 143 ? -11.336 -22.718 57.741 1.00 27.40  ? 345 PHE A CE1 1 
ATOM   1029  C CE2 . PHE A 1 143 ? -10.291 -24.740 57.059 1.00 28.67  ? 345 PHE A CE2 1 
ATOM   1030  C CZ  . PHE A 1 143 ? -10.858 -23.529 56.743 1.00 28.19  ? 345 PHE A CZ  1 
ATOM   1031  N N   . THR A 1 144 ? -13.434 -23.985 61.843 1.00 28.41  ? 346 THR A N   1 
ATOM   1032  C CA  . THR A 1 144 ? -14.564 -23.106 61.613 1.00 30.55  ? 346 THR A CA  1 
ATOM   1033  C C   . THR A 1 144 ? -14.060 -21.703 61.319 1.00 32.61  ? 346 THR A C   1 
ATOM   1034  O O   . THR A 1 144 ? -13.021 -21.279 61.831 1.00 32.70  ? 346 THR A O   1 
ATOM   1035  C CB  . THR A 1 144 ? -15.496 -23.079 62.824 1.00 33.26  ? 346 THR A CB  1 
ATOM   1036  O OG1 . THR A 1 144 ? -14.774 -22.627 63.974 1.00 36.32  ? 346 THR A OG1 1 
ATOM   1037  C CG2 . THR A 1 144 ? -16.023 -24.461 63.093 1.00 32.99  ? 346 THR A CG2 1 
ATOM   1038  N N   . ASP A 1 145 ? -14.806 -20.977 60.496 1.00 27.68  ? 347 ASP A N   1 
ATOM   1039  C CA  . ASP A 1 145 ? -14.470 -19.591 60.205 1.00 31.08  ? 347 ASP A CA  1 
ATOM   1040  C C   . ASP A 1 145 ? -15.390 -18.745 61.074 1.00 31.32  ? 347 ASP A C   1 
ATOM   1041  O O   . ASP A 1 145 ? -16.567 -18.556 60.767 1.00 31.16  ? 347 ASP A O   1 
ATOM   1042  C CB  . ASP A 1 145 ? -14.644 -19.287 58.723 1.00 27.29  ? 347 ASP A CB  1 
ATOM   1043  C CG  . ASP A 1 145 ? -14.167 -17.899 58.351 1.00 32.85  ? 347 ASP A CG  1 
ATOM   1044  O OD1 . ASP A 1 145 ? -13.591 -17.213 59.221 1.00 33.87  ? 347 ASP A OD1 1 
ATOM   1045  O OD2 . ASP A 1 145 ? -14.379 -17.489 57.192 1.00 35.61  ? 347 ASP A OD2 1 
ATOM   1046  N N   . SER A 1 146 ? -14.833 -18.205 62.154 1.00 34.31  ? 348 SER A N   1 
ATOM   1047  C CA  . SER A 1 146 ? -15.590 -17.355 63.056 1.00 34.35  ? 348 SER A CA  1 
ATOM   1048  C C   . SER A 1 146 ? -15.378 -15.876 62.782 1.00 34.82  ? 348 SER A C   1 
ATOM   1049  O O   . SER A 1 146 ? -16.052 -15.045 63.398 1.00 34.76  ? 348 SER A O   1 
ATOM   1050  C CB  . SER A 1 146 ? -15.220 -17.668 64.510 1.00 34.02  ? 348 SER A CB  1 
ATOM   1051  O OG  . SER A 1 146 ? -13.853 -17.397 64.754 1.00 37.59  ? 348 SER A OG  1 
ATOM   1052  N N   . ASP A 1 147 ? -14.464 -15.533 61.880 1.00 34.27  ? 349 ASP A N   1 
ATOM   1053  C CA  . ASP A 1 147 ? -14.305 -14.172 61.398 1.00 34.71  ? 349 ASP A CA  1 
ATOM   1054  C C   . ASP A 1 147 ? -15.006 -13.951 60.069 1.00 32.59  ? 349 ASP A C   1 
ATOM   1055  O O   . ASP A 1 147 ? -14.964 -12.837 59.539 1.00 32.28  ? 349 ASP A O   1 
ATOM   1056  C CB  . ASP A 1 147 ? -12.821 -13.826 61.278 1.00 32.61  ? 349 ASP A CB  1 
ATOM   1057  C CG  . ASP A 1 147 ? -12.131 -13.763 62.624 1.00 38.48  ? 349 ASP A CG  1 
ATOM   1058  O OD1 . ASP A 1 147 ? -12.839 -13.698 63.650 1.00 41.73  ? 349 ASP A OD1 1 
ATOM   1059  O OD2 . ASP A 1 147 ? -10.884 -13.778 62.658 1.00 42.39  ? 349 ASP A OD2 1 
ATOM   1060  N N   . TYR A 1 148 ? -15.632 -14.993 59.519 1.00 31.10  ? 350 TYR A N   1 
ATOM   1061  C CA  . TYR A 1 148 ? -16.443 -14.902 58.307 1.00 29.12  ? 350 TYR A CA  1 
ATOM   1062  C C   . TYR A 1 148 ? -15.610 -14.414 57.126 1.00 28.52  ? 350 TYR A C   1 
ATOM   1063  O O   . TYR A 1 148 ? -16.061 -13.612 56.308 1.00 28.74  ? 350 TYR A O   1 
ATOM   1064  C CB  . TYR A 1 148 ? -17.665 -14.015 58.542 1.00 31.15  ? 350 TYR A CB  1 
ATOM   1065  C CG  . TYR A 1 148 ? -18.533 -14.540 59.662 1.00 31.24  ? 350 TYR A CG  1 
ATOM   1066  C CD1 . TYR A 1 148 ? -19.523 -15.478 59.420 1.00 31.94  ? 350 TYR A CD1 1 
ATOM   1067  C CD2 . TYR A 1 148 ? -18.341 -14.116 60.969 1.00 29.97  ? 350 TYR A CD2 1 
ATOM   1068  C CE1 . TYR A 1 148 ? -20.304 -15.968 60.445 1.00 31.83  ? 350 TYR A CE1 1 
ATOM   1069  C CE2 . TYR A 1 148 ? -19.117 -14.601 61.999 1.00 29.89  ? 350 TYR A CE2 1 
ATOM   1070  C CZ  . TYR A 1 148 ? -20.097 -15.526 61.732 1.00 31.52  ? 350 TYR A CZ  1 
ATOM   1071  O OH  . TYR A 1 148 ? -20.871 -16.008 62.760 1.00 33.21  ? 350 TYR A OH  1 
ATOM   1072  N N   . GLN A 1 149 ? -14.378 -14.910 57.044 1.00 27.53  ? 351 GLN A N   1 
ATOM   1073  C CA  . GLN A 1 149 ? -13.418 -14.463 56.045 1.00 27.36  ? 351 GLN A CA  1 
ATOM   1074  C C   . GLN A 1 149 ? -13.486 -15.241 54.740 1.00 26.98  ? 351 GLN A C   1 
ATOM   1075  O O   . GLN A 1 149 ? -12.939 -14.778 53.734 1.00 29.07  ? 351 GLN A O   1 
ATOM   1076  C CB  . GLN A 1 149 ? -12.012 -14.550 56.636 1.00 26.68  ? 351 GLN A CB  1 
ATOM   1077  C CG  . GLN A 1 149 ? -11.794 -13.553 57.757 1.00 27.51  ? 351 GLN A CG  1 
ATOM   1078  C CD  . GLN A 1 149 ? -10.520 -13.797 58.531 1.00 29.87  ? 351 GLN A CD  1 
ATOM   1079  O OE1 . GLN A 1 149 ? -10.053 -14.928 58.639 1.00 32.21  ? 351 GLN A OE1 1 
ATOM   1080  N NE2 . GLN A 1 149 ? -9.945  -12.733 59.072 1.00 29.58  ? 351 GLN A NE2 1 
ATOM   1081  N N   . LEU A 1 150 ? -14.127 -16.394 54.728 1.00 27.41  ? 352 LEU A N   1 
ATOM   1082  C CA  . LEU A 1 150 ? -14.350 -17.172 53.520 1.00 26.06  ? 352 LEU A CA  1 
ATOM   1083  C C   . LEU A 1 150 ? -15.689 -16.831 52.887 1.00 26.08  ? 352 LEU A C   1 
ATOM   1084  O O   . LEU A 1 150 ? -16.599 -16.338 53.557 1.00 27.02  ? 352 LEU A O   1 
ATOM   1085  C CB  . LEU A 1 150 ? -14.293 -18.664 53.837 1.00 26.45  ? 352 LEU A CB  1 
ATOM   1086  C CG  . LEU A 1 150 ? -12.920 -19.231 54.177 1.00 27.13  ? 352 LEU A CG  1 
ATOM   1087  C CD1 . LEU A 1 150 ? -13.048 -20.653 54.671 1.00 26.62  ? 352 LEU A CD1 1 
ATOM   1088  C CD2 . LEU A 1 150 ? -12.057 -19.182 52.936 1.00 25.40  ? 352 LEU A CD2 1 
ATOM   1089  N N   . PRO A 1 151 ? -15.837 -17.081 51.588 1.00 25.40  ? 353 PRO A N   1 
ATOM   1090  C CA  . PRO A 1 151 ? -17.165 -17.000 50.972 1.00 24.38  ? 353 PRO A CA  1 
ATOM   1091  C C   . PRO A 1 151 ? -18.147 -17.922 51.676 1.00 24.85  ? 353 PRO A C   1 
ATOM   1092  O O   . PRO A 1 151 ? -17.832 -19.071 51.988 1.00 24.71  ? 353 PRO A O   1 
ATOM   1093  C CB  . PRO A 1 151 ? -16.907 -17.447 49.533 1.00 20.00  ? 353 PRO A CB  1 
ATOM   1094  C CG  . PRO A 1 151 ? -15.495 -17.082 49.287 1.00 19.58  ? 353 PRO A CG  1 
ATOM   1095  C CD  . PRO A 1 151 ? -14.785 -17.324 50.586 1.00 19.69  ? 353 PRO A CD  1 
ATOM   1096  N N   . TYR A 1 152 ? -19.348 -17.412 51.920 1.00 25.68  ? 354 TYR A N   1 
ATOM   1097  C CA  . TYR A 1 152 ? -20.331 -18.095 52.751 1.00 26.27  ? 354 TYR A CA  1 
ATOM   1098  C C   . TYR A 1 152 ? -21.364 -18.747 51.838 1.00 27.70  ? 354 TYR A C   1 
ATOM   1099  O O   . TYR A 1 152 ? -22.192 -18.057 51.237 1.00 29.18  ? 354 TYR A O   1 
ATOM   1100  C CB  . TYR A 1 152 ? -20.985 -17.103 53.708 1.00 27.06  ? 354 TYR A CB  1 
ATOM   1101  C CG  . TYR A 1 152 ? -21.906 -17.719 54.723 1.00 28.06  ? 354 TYR A CG  1 
ATOM   1102  C CD1 . TYR A 1 152 ? -21.405 -18.245 55.901 1.00 28.07  ? 354 TYR A CD1 1 
ATOM   1103  C CD2 . TYR A 1 152 ? -23.271 -17.788 54.503 1.00 27.53  ? 354 TYR A CD2 1 
ATOM   1104  C CE1 . TYR A 1 152 ? -22.235 -18.805 56.838 1.00 29.20  ? 354 TYR A CE1 1 
ATOM   1105  C CE2 . TYR A 1 152 ? -24.111 -18.355 55.434 1.00 28.83  ? 354 TYR A CE2 1 
ATOM   1106  C CZ  . TYR A 1 152 ? -23.586 -18.860 56.601 1.00 30.54  ? 354 TYR A CZ  1 
ATOM   1107  O OH  . TYR A 1 152 ? -24.415 -19.426 57.537 1.00 31.38  ? 354 TYR A OH  1 
ATOM   1108  N N   . VAL A 1 153 ? -21.312 -20.077 51.734 1.00 30.41  ? 355 VAL A N   1 
ATOM   1109  C CA  . VAL A 1 153 ? -22.194 -20.826 50.844 1.00 30.51  ? 355 VAL A CA  1 
ATOM   1110  C C   . VAL A 1 153 ? -23.380 -21.451 51.566 1.00 31.85  ? 355 VAL A C   1 
ATOM   1111  O O   . VAL A 1 153 ? -24.210 -22.100 50.917 1.00 31.74  ? 355 VAL A O   1 
ATOM   1112  C CB  . VAL A 1 153 ? -21.415 -21.915 50.081 1.00 25.53  ? 355 VAL A CB  1 
ATOM   1113  C CG1 . VAL A 1 153 ? -20.340 -21.287 49.216 1.00 27.33  ? 355 VAL A CG1 1 
ATOM   1114  C CG2 . VAL A 1 153 ? -20.823 -22.925 51.048 1.00 24.36  ? 355 VAL A CG2 1 
ATOM   1115  N N   . LEU A 1 154 ? -23.486 -21.290 52.885 1.00 31.15  ? 356 LEU A N   1 
ATOM   1116  C CA  . LEU A 1 154 ? -24.535 -21.974 53.635 1.00 32.63  ? 356 LEU A CA  1 
ATOM   1117  C C   . LEU A 1 154 ? -25.914 -21.355 53.452 1.00 35.05  ? 356 LEU A C   1 
ATOM   1118  O O   . LEU A 1 154 ? -26.890 -21.909 53.967 1.00 37.20  ? 356 LEU A O   1 
ATOM   1119  C CB  . LEU A 1 154 ? -24.196 -22.003 55.125 1.00 33.69  ? 356 LEU A CB  1 
ATOM   1120  C CG  . LEU A 1 154 ? -22.983 -22.820 55.561 1.00 32.43  ? 356 LEU A CG  1 
ATOM   1121  C CD1 . LEU A 1 154 ? -22.738 -22.643 57.049 1.00 32.08  ? 356 LEU A CD1 1 
ATOM   1122  C CD2 . LEU A 1 154 ? -23.183 -24.281 55.221 1.00 31.52  ? 356 LEU A CD2 1 
ATOM   1123  N N   . GLY A 1 155 ? -26.021 -20.244 52.738 1.00 32.76  ? 357 GLY A N   1 
ATOM   1124  C CA  . GLY A 1 155 ? -27.315 -19.616 52.557 1.00 34.52  ? 357 GLY A CA  1 
ATOM   1125  C C   . GLY A 1 155 ? -27.887 -19.751 51.164 1.00 33.83  ? 357 GLY A C   1 
ATOM   1126  O O   . GLY A 1 155 ? -28.726 -18.958 50.755 1.00 32.66  ? 357 GLY A O   1 
ATOM   1127  N N   . SER A 1 156 ? -27.436 -20.756 50.430 1.00 35.31  ? 358 SER A N   1 
ATOM   1128  C CA  . SER A 1 156 ? -27.901 -20.959 49.067 1.00 32.63  ? 358 SER A CA  1 
ATOM   1129  C C   . SER A 1 156 ? -28.863 -22.121 48.885 1.00 32.16  ? 358 SER A C   1 
ATOM   1130  O O   . SER A 1 156 ? -29.098 -22.551 47.758 1.00 31.76  ? 358 SER A O   1 
ATOM   1131  C CB  . SER A 1 156 ? -26.719 -21.078 48.112 1.00 32.54  ? 358 SER A CB  1 
ATOM   1132  O OG  . SER A 1 156 ? -25.980 -19.871 48.089 1.00 34.53  ? 358 SER A OG  1 
ATOM   1133  N N   . ALA A 1 157 ? -29.376 -22.642 49.996 1.00 34.94  ? 359 ALA A N   1 
ATOM   1134  C CA  . ALA A 1 157 ? -30.320 -23.764 50.002 1.00 33.45  ? 359 ALA A CA  1 
ATOM   1135  C C   . ALA A 1 157 ? -29.794 -24.997 49.277 1.00 33.54  ? 359 ALA A C   1 
ATOM   1136  O O   . ALA A 1 157 ? -30.510 -25.643 48.524 1.00 33.20  ? 359 ALA A O   1 
ATOM   1137  C CB  . ALA A 1 157 ? -31.688 -23.352 49.474 1.00 33.02  ? 359 ALA A CB  1 
ATOM   1138  N N   . HIS A 1 158 ? -28.522 -25.292 49.502 1.00 34.20  ? 360 HIS A N   1 
ATOM   1139  C CA  . HIS A 1 158 ? -27.846 -26.437 48.913 1.00 35.04  ? 360 HIS A CA  1 
ATOM   1140  C C   . HIS A 1 158 ? -28.155 -27.762 49.582 1.00 37.07  ? 360 HIS A C   1 
ATOM   1141  O O   . HIS A 1 158 ? -28.613 -27.813 50.719 1.00 37.85  ? 360 HIS A O   1 
ATOM   1142  C CB  . HIS A 1 158 ? -26.340 -26.230 48.965 1.00 28.93  ? 360 HIS A CB  1 
ATOM   1143  C CG  . HIS A 1 158 ? -25.841 -25.199 48.009 1.00 30.72  ? 360 HIS A CG  1 
ATOM   1144  N ND1 . HIS A 1 158 ? -26.132 -25.233 46.665 1.00 30.84  ? 360 HIS A ND1 1 
ATOM   1145  C CD2 . HIS A 1 158 ? -25.055 -24.116 48.198 1.00 31.98  ? 360 HIS A CD2 1 
ATOM   1146  C CE1 . HIS A 1 158 ? -25.561 -24.207 46.068 1.00 31.77  ? 360 HIS A CE1 1 
ATOM   1147  N NE2 . HIS A 1 158 ? -24.898 -23.515 46.975 1.00 32.51  ? 360 HIS A NE2 1 
ATOM   1148  N N   . GLU A 1 159 ? -27.897 -28.837 48.847 1.00 39.73  ? 361 GLU A N   1 
ATOM   1149  C CA  . GLU A 1 159 ? -28.051 -30.203 49.328 1.00 41.87  ? 361 GLU A CA  1 
ATOM   1150  C C   . GLU A 1 159 ? -26.828 -30.588 50.157 1.00 41.53  ? 361 GLU A C   1 
ATOM   1151  O O   . GLU A 1 159 ? -25.822 -29.892 50.151 1.00 41.57  ? 361 GLU A O   1 
ATOM   1152  C CB  . GLU A 1 159 ? -28.221 -31.167 48.162 1.00 38.03  ? 361 GLU A CB  1 
ATOM   1153  C CG  . GLU A 1 159 ? -29.641 -31.259 47.637 1.00 48.00  ? 361 GLU A CG  1 
ATOM   1154  C CD  . GLU A 1 159 ? -29.706 -31.928 46.283 1.00 52.68  ? 361 GLU A CD  1 
ATOM   1155  O OE1 . GLU A 1 159 ? -30.795 -31.944 45.670 1.00 54.70  ? 361 GLU A OE1 1 
ATOM   1156  O OE2 . GLU A 1 159 ? -28.660 -32.436 45.830 1.00 54.55  ? 361 GLU A OE2 1 
ATOM   1157  N N   . GLY A 1 160 ? -26.886 -31.716 50.847 1.00 46.37  ? 362 GLY A N   1 
ATOM   1158  C CA  . GLY A 1 160 ? -25.757 -32.125 51.661 1.00 45.75  ? 362 GLY A CA  1 
ATOM   1159  C C   . GLY A 1 160 ? -25.902 -31.893 53.147 1.00 45.46  ? 362 GLY A C   1 
ATOM   1160  O O   . GLY A 1 160 ? -24.959 -32.076 53.907 1.00 45.40  ? 362 GLY A O   1 
ATOM   1161  N N   . CYS A 1 161 ? -27.095 -31.488 53.562 1.00 44.90  ? 363 CYS A N   1 
ATOM   1162  C CA  . CYS A 1 161 ? -27.419 -31.290 54.971 1.00 45.08  ? 363 CYS A CA  1 
ATOM   1163  C C   . CYS A 1 161 ? -27.627 -32.638 55.667 1.00 42.63  ? 363 CYS A C   1 
ATOM   1164  O O   . CYS A 1 161 ? -27.806 -33.671 55.017 1.00 42.11  ? 363 CYS A O   1 
ATOM   1165  C CB  . CYS A 1 161 ? -28.691 -30.454 55.127 1.00 45.43  ? 363 CYS A CB  1 
ATOM   1166  S SG  . CYS A 1 161 ? -28.462 -28.662 55.195 1.00 54.51  ? 363 CYS A SG  1 
ATOM   1167  N N   . LEU A 1 162 ? -27.623 -32.638 56.996 1.00 46.36  ? 364 LEU A N   1 
ATOM   1168  C CA  . LEU A 1 162 ? -27.848 -33.874 57.731 1.00 45.26  ? 364 LEU A CA  1 
ATOM   1169  C C   . LEU A 1 162 ? -29.228 -34.402 57.362 1.00 44.92  ? 364 LEU A C   1 
ATOM   1170  O O   . LEU A 1 162 ? -30.192 -33.649 57.313 1.00 44.97  ? 364 LEU A O   1 
ATOM   1171  C CB  . LEU A 1 162 ? -27.807 -33.611 59.231 1.00 42.28  ? 364 LEU A CB  1 
ATOM   1172  C CG  . LEU A 1 162 ? -26.448 -33.409 59.888 1.00 43.01  ? 364 LEU A CG  1 
ATOM   1173  C CD1 . LEU A 1 162 ? -25.676 -32.294 59.209 1.00 42.46  ? 364 LEU A CD1 1 
ATOM   1174  C CD2 . LEU A 1 162 ? -26.620 -33.129 61.370 1.00 41.75  ? 364 LEU A CD2 1 
ATOM   1175  N N   . PRO A 1 163 ? -29.342 -35.715 57.140 1.00 47.45  ? 365 PRO A N   1 
ATOM   1176  C CA  . PRO A 1 163 ? -30.632 -36.291 56.748 1.00 46.59  ? 365 PRO A CA  1 
ATOM   1177  C C   . PRO A 1 163 ? -31.703 -36.168 57.827 1.00 45.85  ? 365 PRO A C   1 
ATOM   1178  O O   . PRO A 1 163 ? -31.388 -36.117 59.016 1.00 45.98  ? 365 PRO A O   1 
ATOM   1179  C CB  . PRO A 1 163 ? -30.296 -37.760 56.494 1.00 47.77  ? 365 PRO A CB  1 
ATOM   1180  C CG  . PRO A 1 163 ? -29.099 -38.018 57.332 1.00 48.26  ? 365 PRO A CG  1 
ATOM   1181  C CD  . PRO A 1 163 ? -28.308 -36.744 57.321 1.00 47.45  ? 365 PRO A CD  1 
ATOM   1182  N N   . PRO A 1 164 ? -32.974 -36.119 57.412 1.00 47.22  ? 366 PRO A N   1 
ATOM   1183  C CA  . PRO A 1 164 ? -34.043 -36.010 58.415 1.00 46.77  ? 366 PRO A CA  1 
ATOM   1184  C C   . PRO A 1 164 ? -34.131 -37.209 59.336 1.00 47.17  ? 366 PRO A C   1 
ATOM   1185  O O   . PRO A 1 164 ? -34.376 -37.039 60.536 1.00 47.33  ? 366 PRO A O   1 
ATOM   1186  C CB  . PRO A 1 164 ? -35.306 -35.860 57.558 1.00 43.97  ? 366 PRO A CB  1 
ATOM   1187  C CG  . PRO A 1 164 ? -34.960 -36.519 56.276 1.00 44.05  ? 366 PRO A CG  1 
ATOM   1188  C CD  . PRO A 1 164 ? -33.509 -36.226 56.045 1.00 44.27  ? 366 PRO A CD  1 
ATOM   1189  N N   . PHE A 1 165 ? -33.931 -38.418 58.818 1.00 49.84  ? 367 PHE A N   1 
ATOM   1190  C CA  . PHE A 1 165 ? -34.117 -39.599 59.646 1.00 50.78  ? 367 PHE A CA  1 
ATOM   1191  C C   . PHE A 1 165 ? -32.802 -39.978 60.308 1.00 51.76  ? 367 PHE A C   1 
ATOM   1192  O O   . PHE A 1 165 ? -31.760 -39.995 59.638 1.00 51.59  ? 367 PHE A O   1 
ATOM   1193  C CB  . PHE A 1 165 ? -34.647 -40.761 58.809 1.00 54.19  ? 367 PHE A CB  1 
ATOM   1194  C CG  . PHE A 1 165 ? -34.985 -41.983 59.609 1.00 55.51  ? 367 PHE A CG  1 
ATOM   1195  C CD1 . PHE A 1 165 ? -36.149 -42.032 60.355 1.00 56.23  ? 367 PHE A CD1 1 
ATOM   1196  C CD2 . PHE A 1 165 ? -34.158 -43.089 59.598 1.00 55.61  ? 367 PHE A CD2 1 
ATOM   1197  C CE1 . PHE A 1 165 ? -36.470 -43.151 61.091 1.00 56.85  ? 367 PHE A CE1 1 
ATOM   1198  C CE2 . PHE A 1 165 ? -34.481 -44.214 60.329 1.00 56.32  ? 367 PHE A CE2 1 
ATOM   1199  C CZ  . PHE A 1 165 ? -35.636 -44.244 61.078 1.00 56.99  ? 367 PHE A CZ  1 
ATOM   1200  N N   . PRO A 1 166 ? -32.815 -40.272 61.612 1.00 51.69  ? 368 PRO A N   1 
ATOM   1201  C CA  . PRO A 1 166 ? -31.551 -40.392 62.359 1.00 51.98  ? 368 PRO A CA  1 
ATOM   1202  C C   . PRO A 1 166 ? -30.662 -41.549 61.937 1.00 52.80  ? 368 PRO A C   1 
ATOM   1203  O O   . PRO A 1 166 ? -29.438 -41.437 62.068 1.00 53.99  ? 368 PRO A O   1 
ATOM   1204  C CB  . PRO A 1 166 ? -32.024 -40.563 63.808 1.00 50.26  ? 368 PRO A CB  1 
ATOM   1205  C CG  . PRO A 1 166 ? -33.356 -39.898 63.839 1.00 50.64  ? 368 PRO A CG  1 
ATOM   1206  C CD  . PRO A 1 166 ? -33.979 -40.209 62.510 1.00 50.95  ? 368 PRO A CD  1 
ATOM   1207  N N   . ALA A 1 167 ? -31.218 -42.653 61.451 1.00 56.68  ? 369 ALA A N   1 
ATOM   1208  C CA  . ALA A 1 167 ? -30.404 -43.816 61.127 1.00 56.86  ? 369 ALA A CA  1 
ATOM   1209  C C   . ALA A 1 167 ? -29.673 -43.690 59.798 1.00 57.89  ? 369 ALA A C   1 
ATOM   1210  O O   . ALA A 1 167 ? -28.843 -44.551 59.486 1.00 58.38  ? 369 ALA A O   1 
ATOM   1211  C CB  . ALA A 1 167 ? -31.265 -45.081 61.112 1.00 57.64  ? 369 ALA A CB  1 
ATOM   1212  N N   . ASP A 1 168 ? -29.950 -42.654 59.015 1.00 53.99  ? 370 ASP A N   1 
ATOM   1213  C CA  . ASP A 1 168 ? -29.303 -42.498 57.723 1.00 56.20  ? 370 ASP A CA  1 
ATOM   1214  C C   . ASP A 1 168 ? -27.836 -42.119 57.890 1.00 54.19  ? 370 ASP A C   1 
ATOM   1215  O O   . ASP A 1 168 ? -27.418 -41.585 58.921 1.00 54.48  ? 370 ASP A O   1 
ATOM   1216  C CB  . ASP A 1 168 ? -30.015 -41.438 56.884 1.00 52.89  ? 370 ASP A CB  1 
ATOM   1217  C CG  . ASP A 1 168 ? -31.382 -41.882 56.418 1.00 59.12  ? 370 ASP A CG  1 
ATOM   1218  O OD1 . ASP A 1 168 ? -31.677 -43.091 56.500 1.00 61.68  ? 370 ASP A OD1 1 
ATOM   1219  O OD2 . ASP A 1 168 ? -32.159 -41.023 55.952 1.00 62.07  ? 370 ASP A OD2 1 
ATOM   1220  N N   . VAL A 1 169 ? -27.053 -42.405 56.854 1.00 48.67  ? 371 VAL A N   1 
ATOM   1221  C CA  . VAL A 1 169 ? -25.638 -42.060 56.797 1.00 45.61  ? 371 VAL A CA  1 
ATOM   1222  C C   . VAL A 1 169 ? -25.424 -41.161 55.588 1.00 45.15  ? 371 VAL A C   1 
ATOM   1223  O O   . VAL A 1 169 ? -25.701 -41.566 54.453 1.00 45.03  ? 371 VAL A O   1 
ATOM   1224  C CB  . VAL A 1 169 ? -24.758 -43.318 56.716 1.00 46.77  ? 371 VAL A CB  1 
ATOM   1225  C CG1 . VAL A 1 169 ? -23.298 -42.935 56.545 1.00 45.47  ? 371 VAL A CG1 1 
ATOM   1226  C CG2 . VAL A 1 169 ? -24.950 -44.175 57.955 1.00 45.83  ? 371 VAL A CG2 1 
ATOM   1227  N N   . PHE A 1 170 ? -24.922 -39.952 55.825 1.00 39.24  ? 372 PHE A N   1 
ATOM   1228  C CA  . PHE A 1 170 ? -24.861 -38.935 54.789 1.00 39.37  ? 372 PHE A CA  1 
ATOM   1229  C C   . PHE A 1 170 ? -23.417 -38.677 54.380 1.00 40.01  ? 372 PHE A C   1 
ATOM   1230  O O   . PHE A 1 170 ? -22.480 -38.861 55.160 1.00 39.91  ? 372 PHE A O   1 
ATOM   1231  C CB  . PHE A 1 170 ? -25.517 -37.622 55.248 1.00 38.46  ? 372 PHE A CB  1 
ATOM   1232  C CG  . PHE A 1 170 ? -24.763 -36.898 56.334 1.00 38.64  ? 372 PHE A CG  1 
ATOM   1233  C CD1 . PHE A 1 170 ? -23.853 -35.905 56.014 1.00 38.17  ? 372 PHE A CD1 1 
ATOM   1234  C CD2 . PHE A 1 170 ? -24.957 -37.208 57.667 1.00 38.91  ? 372 PHE A CD2 1 
ATOM   1235  C CE1 . PHE A 1 170 ? -23.159 -35.235 56.998 1.00 38.05  ? 372 PHE A CE1 1 
ATOM   1236  C CE2 . PHE A 1 170 ? -24.261 -36.537 58.653 1.00 38.35  ? 372 PHE A CE2 1 
ATOM   1237  C CZ  . PHE A 1 170 ? -23.364 -35.553 58.318 1.00 37.68  ? 372 PHE A CZ  1 
ATOM   1238  N N   . MET A 1 171 ? -23.256 -38.253 53.133 1.00 38.35  ? 373 MET A N   1 
ATOM   1239  C CA  . MET A 1 171 ? -21.964 -37.887 52.574 1.00 38.21  ? 373 MET A CA  1 
ATOM   1240  C C   . MET A 1 171 ? -21.774 -36.378 52.667 1.00 36.52  ? 373 MET A C   1 
ATOM   1241  O O   . MET A 1 171 ? -22.710 -35.608 52.434 1.00 37.73  ? 373 MET A O   1 
ATOM   1242  C CB  . MET A 1 171 ? -21.867 -38.350 51.120 1.00 34.25  ? 373 MET A CB  1 
ATOM   1243  C CG  . MET A 1 171 ? -20.569 -38.018 50.417 1.00 38.95  ? 373 MET A CG  1 
ATOM   1244  S SD  . MET A 1 171 ? -20.532 -38.800 48.797 1.00 44.00  ? 373 MET A SD  1 
ATOM   1245  C CE  . MET A 1 171 ? -19.060 -38.076 48.098 1.00 45.91  ? 373 MET A CE  1 
ATOM   1246  N N   . ILE A 1 172 ? -20.562 -35.965 53.009 1.00 33.82  ? 374 ILE A N   1 
ATOM   1247  C CA  . ILE A 1 172 ? -20.264 -34.545 53.210 1.00 32.49  ? 374 ILE A CA  1 
ATOM   1248  C C   . ILE A 1 172 ? -19.979 -33.902 51.855 1.00 31.82  ? 374 ILE A C   1 
ATOM   1249  O O   . ILE A 1 172 ? -19.151 -34.424 51.096 1.00 32.40  ? 374 ILE A O   1 
ATOM   1250  C CB  . ILE A 1 172 ? -19.082 -34.381 54.156 1.00 30.60  ? 374 ILE A CB  1 
ATOM   1251  C CG1 . ILE A 1 172 ? -19.461 -34.875 55.550 1.00 31.68  ? 374 ILE A CG1 1 
ATOM   1252  C CG2 . ILE A 1 172 ? -18.624 -32.942 54.210 1.00 29.82  ? 374 ILE A CG2 1 
ATOM   1253  C CD1 . ILE A 1 172 ? -18.298 -34.956 56.483 1.00 35.83  ? 374 ILE A CD1 1 
ATOM   1254  N N   . PRO A 1 173 ? -20.628 -32.791 51.517 1.00 27.23  ? 375 PRO A N   1 
ATOM   1255  C CA  . PRO A 1 173 ? -20.450 -32.203 50.187 1.00 27.36  ? 375 PRO A CA  1 
ATOM   1256  C C   . PRO A 1 173 ? -19.140 -31.445 50.049 1.00 27.68  ? 375 PRO A C   1 
ATOM   1257  O O   . PRO A 1 173 ? -18.551 -30.977 51.025 1.00 28.39  ? 375 PRO A O   1 
ATOM   1258  C CB  . PRO A 1 173 ? -21.646 -31.252 50.069 1.00 29.11  ? 375 PRO A CB  1 
ATOM   1259  C CG  . PRO A 1 173 ? -21.931 -30.854 51.467 1.00 28.71  ? 375 PRO A CG  1 
ATOM   1260  C CD  . PRO A 1 173 ? -21.617 -32.052 52.320 1.00 29.09  ? 375 PRO A CD  1 
ATOM   1261  N N   . GLN A 1 174 ? -18.696 -31.316 48.803 1.00 23.54  ? 376 GLN A N   1 
ATOM   1262  C CA  . GLN A 1 174 ? -17.453 -30.623 48.506 1.00 22.84  ? 376 GLN A CA  1 
ATOM   1263  C C   . GLN A 1 174 ? -17.637 -29.116 48.607 1.00 23.09  ? 376 GLN A C   1 
ATOM   1264  O O   . GLN A 1 174 ? -18.657 -28.563 48.186 1.00 23.37  ? 376 GLN A O   1 
ATOM   1265  C CB  . GLN A 1 174 ? -16.956 -30.980 47.107 1.00 19.07  ? 376 GLN A CB  1 
ATOM   1266  C CG  . GLN A 1 174 ? -15.569 -30.457 46.807 1.00 19.55  ? 376 GLN A CG  1 
ATOM   1267  C CD  . GLN A 1 174 ? -15.054 -30.903 45.461 1.00 21.93  ? 376 GLN A CD  1 
ATOM   1268  O OE1 . GLN A 1 174 ? -15.713 -31.656 44.752 1.00 23.30  ? 376 GLN A OE1 1 
ATOM   1269  N NE2 . GLN A 1 174 ? -13.863 -30.451 45.106 1.00 22.57  ? 376 GLN A NE2 1 
ATOM   1270  N N   . TYR A 1 175 ? -16.630 -28.449 49.161 1.00 21.16  ? 377 TYR A N   1 
ATOM   1271  C CA  . TYR A 1 175 ? -16.664 -27.004 49.309 1.00 20.40  ? 377 TYR A CA  1 
ATOM   1272  C C   . TYR A 1 175 ? -16.228 -26.333 48.015 1.00 21.23  ? 377 TYR A C   1 
ATOM   1273  O O   . TYR A 1 175 ? -15.290 -26.780 47.351 1.00 21.62  ? 377 TYR A O   1 
ATOM   1274  C CB  . TYR A 1 175 ? -15.765 -26.548 50.456 1.00 20.19  ? 377 TYR A CB  1 
ATOM   1275  C CG  . TYR A 1 175 ? -15.747 -25.050 50.631 1.00 20.45  ? 377 TYR A CG  1 
ATOM   1276  C CD1 . TYR A 1 175 ? -16.782 -24.399 51.282 1.00 20.13  ? 377 TYR A CD1 1 
ATOM   1277  C CD2 . TYR A 1 175 ? -14.708 -24.283 50.129 1.00 20.42  ? 377 TYR A CD2 1 
ATOM   1278  C CE1 . TYR A 1 175 ? -16.775 -23.033 51.441 1.00 20.15  ? 377 TYR A CE1 1 
ATOM   1279  C CE2 . TYR A 1 175 ? -14.694 -22.918 50.281 1.00 20.38  ? 377 TYR A CE2 1 
ATOM   1280  C CZ  . TYR A 1 175 ? -15.729 -22.298 50.937 1.00 21.23  ? 377 TYR A CZ  1 
ATOM   1281  O OH  . TYR A 1 175 ? -15.720 -20.936 51.090 1.00 21.12  ? 377 TYR A OH  1 
ATOM   1282  N N   . GLY A 1 176 ? -16.918 -25.257 47.665 1.00 18.40  ? 378 GLY A N   1 
ATOM   1283  C CA  . GLY A 1 176 ? -16.580 -24.483 46.488 1.00 18.57  ? 378 GLY A CA  1 
ATOM   1284  C C   . GLY A 1 176 ? -17.183 -23.105 46.624 1.00 18.75  ? 378 GLY A C   1 
ATOM   1285  O O   . GLY A 1 176 ? -18.108 -22.889 47.411 1.00 18.50  ? 378 GLY A O   1 
ATOM   1286  N N   . TYR A 1 177 ? -16.646 -22.169 45.852 1.00 12.46  ? 379 TYR A N   1 
ATOM   1287  C CA  . TYR A 1 177 ? -17.120 -20.795 45.907 1.00 12.84  ? 379 TYR A CA  1 
ATOM   1288  C C   . TYR A 1 177 ? -16.909 -20.155 44.545 1.00 13.54  ? 379 TYR A C   1 
ATOM   1289  O O   . TYR A 1 177 ? -16.189 -20.677 43.693 1.00 13.39  ? 379 TYR A O   1 
ATOM   1290  C CB  . TYR A 1 177 ? -16.420 -20.000 47.015 1.00 12.39  ? 379 TYR A CB  1 
ATOM   1291  C CG  . TYR A 1 177 ? -14.934 -19.836 46.823 1.00 13.11  ? 379 TYR A CG  1 
ATOM   1292  C CD1 . TYR A 1 177 ? -14.420 -18.746 46.138 1.00 12.98  ? 379 TYR A CD1 1 
ATOM   1293  C CD2 . TYR A 1 177 ? -14.046 -20.771 47.323 1.00 13.15  ? 379 TYR A CD2 1 
ATOM   1294  C CE1 . TYR A 1 177 ? -13.067 -18.595 45.959 1.00 13.86  ? 379 TYR A CE1 1 
ATOM   1295  C CE2 . TYR A 1 177 ? -12.692 -20.627 47.149 1.00 13.93  ? 379 TYR A CE2 1 
ATOM   1296  C CZ  . TYR A 1 177 ? -12.209 -19.539 46.465 1.00 14.94  ? 379 TYR A CZ  1 
ATOM   1297  O OH  . TYR A 1 177 ? -10.856 -19.396 46.293 1.00 16.09  ? 379 TYR A OH  1 
ATOM   1298  N N   . LEU A 1 178 ? -17.565 -19.019 44.351 1.00 9.66   ? 380 LEU A N   1 
ATOM   1299  C CA  . LEU A 1 178 ? -17.481 -18.263 43.116 1.00 10.68  ? 380 LEU A CA  1 
ATOM   1300  C C   . LEU A 1 178 ? -16.943 -16.872 43.413 1.00 13.02  ? 380 LEU A C   1 
ATOM   1301  O O   . LEU A 1 178 ? -16.940 -16.412 44.556 1.00 14.22  ? 380 LEU A O   1 
ATOM   1302  C CB  . LEU A 1 178 ? -18.842 -18.176 42.421 1.00 15.01  ? 380 LEU A CB  1 
ATOM   1303  C CG  . LEU A 1 178 ? -19.398 -19.493 41.887 1.00 15.39  ? 380 LEU A CG  1 
ATOM   1304  C CD1 . LEU A 1 178 ? -20.813 -19.313 41.398 1.00 14.99  ? 380 LEU A CD1 1 
ATOM   1305  C CD2 . LEU A 1 178 ? -18.516 -20.016 40.776 1.00 14.84  ? 380 LEU A CD2 1 
ATOM   1306  N N   . THR A 1 179 ? -16.467 -16.212 42.363 1.00 13.47  ? 381 THR A N   1 
ATOM   1307  C CA  . THR A 1 179 ? -15.846 -14.903 42.502 1.00 16.00  ? 381 THR A CA  1 
ATOM   1308  C C   . THR A 1 179 ? -16.292 -14.052 41.316 1.00 16.22  ? 381 THR A C   1 
ATOM   1309  O O   . THR A 1 179 ? -17.171 -14.471 40.558 1.00 16.12  ? 381 THR A O   1 
ATOM   1310  C CB  . THR A 1 179 ? -14.323 -15.052 42.576 1.00 13.53  ? 381 THR A CB  1 
ATOM   1311  O OG1 . THR A 1 179 ? -14.003 -16.085 43.511 1.00 15.24  ? 381 THR A OG1 1 
ATOM   1312  C CG2 . THR A 1 179 ? -13.684 -13.803 43.115 1.00 15.44  ? 381 THR A CG2 1 
ATOM   1313  N N   . LEU A 1 180 ? -15.721 -12.863 41.146 1.00 15.67  ? 382 LEU A N   1 
ATOM   1314  C CA  . LEU A 1 180 ? -16.093 -12.012 40.026 1.00 16.17  ? 382 LEU A CA  1 
ATOM   1315  C C   . LEU A 1 180 ? -15.663 -12.645 38.711 1.00 17.76  ? 382 LEU A C   1 
ATOM   1316  O O   . LEU A 1 180 ? -14.702 -13.414 38.658 1.00 18.08  ? 382 LEU A O   1 
ATOM   1317  C CB  . LEU A 1 180 ? -15.460 -10.634 40.180 1.00 15.88  ? 382 LEU A CB  1 
ATOM   1318  C CG  . LEU A 1 180 ? -15.873 -9.851  41.423 1.00 15.34  ? 382 LEU A CG  1 
ATOM   1319  C CD1 . LEU A 1 180 ? -15.112 -8.546  41.502 1.00 15.00  ? 382 LEU A CD1 1 
ATOM   1320  C CD2 . LEU A 1 180 ? -17.366 -9.611  41.427 1.00 14.66  ? 382 LEU A CD2 1 
ATOM   1321  N N   . ASN A 1 181 ? -16.380 -12.311 37.641 1.00 16.27  ? 383 ASN A N   1 
ATOM   1322  C CA  . ASN A 1 181 ? -16.084 -12.866 36.332 1.00 18.34  ? 383 ASN A CA  1 
ATOM   1323  C C   . ASN A 1 181 ? -16.529 -11.907 35.241 1.00 20.99  ? 383 ASN A C   1 
ATOM   1324  O O   . ASN A 1 181 ? -17.404 -11.064 35.448 1.00 21.07  ? 383 ASN A O   1 
ATOM   1325  C CB  . ASN A 1 181 ? -16.777 -14.212 36.118 1.00 22.10  ? 383 ASN A CB  1 
ATOM   1326  C CG  . ASN A 1 181 ? -18.286 -14.108 36.191 1.00 22.43  ? 383 ASN A CG  1 
ATOM   1327  O OD1 . ASN A 1 181 ? -18.829 -13.158 36.744 1.00 23.42  ? 383 ASN A OD1 1 
ATOM   1328  N ND2 . ASN A 1 181 ? -18.971 -15.073 35.606 1.00 22.17  ? 383 ASN A ND2 1 
ATOM   1329  N N   . ASP A 1 182 ? -15.907 -12.051 34.075 1.00 22.31  ? 384 ASP A N   1 
ATOM   1330  C CA  . ASP A 1 182 ? -16.405 -11.489 32.826 1.00 24.92  ? 384 ASP A CA  1 
ATOM   1331  C C   . ASP A 1 182 ? -16.441 -12.638 31.829 1.00 24.02  ? 384 ASP A C   1 
ATOM   1332  O O   . ASP A 1 182 ? -15.389 -13.137 31.416 1.00 24.21  ? 384 ASP A O   1 
ATOM   1333  C CB  . ASP A 1 182 ? -15.519 -10.346 32.338 1.00 24.08  ? 384 ASP A CB  1 
ATOM   1334  C CG  . ASP A 1 182 ? -16.081 -9.651  31.115 1.00 28.40  ? 384 ASP A CG  1 
ATOM   1335  O OD1 . ASP A 1 182 ? -17.196 -10.008 30.679 1.00 31.31  ? 384 ASP A OD1 1 
ATOM   1336  O OD2 . ASP A 1 182 ? -15.409 -8.741  30.587 1.00 30.71  ? 384 ASP A OD2 1 
ATOM   1337  N N   . GLY A 1 183 ? -17.640 -13.047 31.433 1.00 22.96  ? 385 GLY A N   1 
ATOM   1338  C CA  . GLY A 1 183 ? -17.758 -14.303 30.714 1.00 22.02  ? 385 GLY A CA  1 
ATOM   1339  C C   . GLY A 1 183 ? -17.305 -15.432 31.615 1.00 21.62  ? 385 GLY A C   1 
ATOM   1340  O O   . GLY A 1 183 ? -17.687 -15.512 32.786 1.00 21.90  ? 385 GLY A O   1 
ATOM   1341  N N   . SER A 1 184 ? -16.424 -16.275 31.099 1.00 22.76  ? 386 SER A N   1 
ATOM   1342  C CA  . SER A 1 184 ? -15.856 -17.347 31.906 1.00 21.33  ? 386 SER A CA  1 
ATOM   1343  C C   . SER A 1 184 ? -14.515 -16.896 32.484 1.00 20.75  ? 386 SER A C   1 
ATOM   1344  O O   . SER A 1 184 ? -13.977 -17.524 33.385 1.00 20.92  ? 386 SER A O   1 
ATOM   1345  C CB  . SER A 1 184 ? -15.661 -18.603 31.076 1.00 22.31  ? 386 SER A CB  1 
ATOM   1346  O OG  . SER A 1 184 ? -14.679 -18.400 30.086 1.00 24.00  ? 386 SER A OG  1 
ATOM   1347  N N   . GLN A 1 185 ? -13.984 -15.799 31.953 1.00 19.88  ? 387 GLN A N   1 
ATOM   1348  C CA  . GLN A 1 185 ? -12.716 -15.231 32.377 1.00 19.32  ? 387 GLN A CA  1 
ATOM   1349  C C   . GLN A 1 185 ? -12.802 -14.547 33.722 1.00 19.01  ? 387 GLN A C   1 
ATOM   1350  O O   . GLN A 1 185 ? -13.868 -14.149 34.160 1.00 19.12  ? 387 GLN A O   1 
ATOM   1351  C CB  . GLN A 1 185 ? -12.197 -14.254 31.333 1.00 20.06  ? 387 GLN A CB  1 
ATOM   1352  C CG  . GLN A 1 185 ? -11.864 -14.912 30.013 1.00 21.48  ? 387 GLN A CG  1 
ATOM   1353  C CD  . GLN A 1 185 ? -10.959 -14.064 29.157 1.00 23.24  ? 387 GLN A CD  1 
ATOM   1354  O OE1 . GLN A 1 185 ? -11.183 -12.870 28.991 1.00 24.62  ? 387 GLN A OE1 1 
ATOM   1355  N NE2 . GLN A 1 185 ? -9.929  -14.680 28.603 1.00 22.93  ? 387 GLN A NE2 1 
ATOM   1356  N N   . ALA A 1 186 ? -11.656 -14.408 34.369 1.00 19.01  ? 388 ALA A N   1 
ATOM   1357  C CA  . ALA A 1 186 ? -11.577 -13.784 35.675 1.00 18.10  ? 388 ALA A CA  1 
ATOM   1358  C C   . ALA A 1 186 ? -10.999 -12.385 35.589 1.00 18.05  ? 388 ALA A C   1 
ATOM   1359  O O   . ALA A 1 186 ? -9.984  -12.167 34.953 1.00 17.85  ? 388 ALA A O   1 
ATOM   1360  C CB  . ALA A 1 186 ? -10.723 -14.633 36.594 1.00 16.63  ? 388 ALA A CB  1 
ATOM   1361  N N   . VAL A 1 187 ? -11.670 -11.433 36.221 1.00 17.57  ? 389 VAL A N   1 
ATOM   1362  C CA  . VAL A 1 187 ? -11.230 -10.047 36.259 1.00 18.34  ? 389 VAL A CA  1 
ATOM   1363  C C   . VAL A 1 187 ? -10.134 -9.855  37.296 1.00 17.94  ? 389 VAL A C   1 
ATOM   1364  O O   . VAL A 1 187 ? -9.889  -10.732 38.114 1.00 17.91  ? 389 VAL A O   1 
ATOM   1365  C CB  . VAL A 1 187 ? -12.390 -9.091  36.556 1.00 17.58  ? 389 VAL A CB  1 
ATOM   1366  C CG1 . VAL A 1 187 ? -13.382 -9.111  35.412 1.00 20.44  ? 389 VAL A CG1 1 
ATOM   1367  C CG2 . VAL A 1 187 ? -13.060 -9.466  37.862 1.00 17.30  ? 389 VAL A CG2 1 
ATOM   1368  N N   . GLY A 1 188 ? -9.482  -8.701  37.270 1.00 18.41  ? 390 GLY A N   1 
ATOM   1369  C CA  . GLY A 1 188 ? -8.404  -8.404  38.193 1.00 17.67  ? 390 GLY A CA  1 
ATOM   1370  C C   . GLY A 1 188 ? -8.837  -8.416  39.641 1.00 17.65  ? 390 GLY A C   1 
ATOM   1371  O O   . GLY A 1 188 ? -8.106  -8.859  40.511 1.00 17.68  ? 390 GLY A O   1 
ATOM   1372  N N   . ARG A 1 189 ? -10.038 -7.921  39.901 1.00 18.77  ? 391 ARG A N   1 
ATOM   1373  C CA  . ARG A 1 189 ? -10.610 -7.856  41.243 1.00 17.78  ? 391 ARG A CA  1 
ATOM   1374  C C   . ARG A 1 189 ? -10.939 -9.208  41.881 1.00 16.28  ? 391 ARG A C   1 
ATOM   1375  O O   . ARG A 1 189 ? -11.059 -9.307  43.090 1.00 16.96  ? 391 ARG A O   1 
ATOM   1376  C CB  . ARG A 1 189 ? -11.830 -6.939  41.253 1.00 14.23  ? 391 ARG A CB  1 
ATOM   1377  C CG  . ARG A 1 189 ? -11.997 -6.183  42.554 1.00 18.01  ? 391 ARG A CG  1 
ATOM   1378  C CD  . ARG A 1 189 ? -13.069 -5.114  42.468 1.00 21.29  ? 391 ARG A CD  1 
ATOM   1379  N NE  . ARG A 1 189 ? -12.597 -3.885  41.843 1.00 25.33  ? 391 ARG A NE  1 
ATOM   1380  C CZ  . ARG A 1 189 ? -13.267 -3.226  40.908 1.00 27.43  ? 391 ARG A CZ  1 
ATOM   1381  N NH1 . ARG A 1 189 ? -14.439 -3.676  40.495 1.00 27.97  ? 391 ARG A NH1 1 
ATOM   1382  N NH2 . ARG A 1 189 ? -12.773 -2.113  40.396 1.00 29.04  ? 391 ARG A NH2 1 
ATOM   1383  N N   . SER A 1 190 ? -11.107 -10.236 41.059 1.00 15.81  ? 392 SER A N   1 
ATOM   1384  C CA  . SER A 1 190 ? -11.441 -11.575 41.515 1.00 14.58  ? 392 SER A CA  1 
ATOM   1385  C C   . SER A 1 190 ? -10.396 -12.104 42.480 1.00 14.58  ? 392 SER A C   1 
ATOM   1386  O O   . SER A 1 190 ? -9.209  -11.982 42.238 1.00 14.03  ? 392 SER A O   1 
ATOM   1387  C CB  . SER A 1 190 ? -11.522 -12.480 40.291 1.00 15.16  ? 392 SER A CB  1 
ATOM   1388  O OG  . SER A 1 190 ? -11.083 -13.789 40.574 1.00 16.17  ? 392 SER A OG  1 
ATOM   1389  N N   . SER A 1 191 ? -10.843 -12.723 43.565 1.00 14.73  ? 393 SER A N   1 
ATOM   1390  C CA  . SER A 1 191 ? -9.913  -13.229 44.563 1.00 13.22  ? 393 SER A CA  1 
ATOM   1391  C C   . SER A 1 191 ? -9.863  -14.736 44.689 1.00 12.59  ? 393 SER A C   1 
ATOM   1392  O O   . SER A 1 191 ? -10.802 -15.439 44.364 1.00 13.01  ? 393 SER A O   1 
ATOM   1393  C CB  . SER A 1 191 ? -10.181 -12.611 45.929 1.00 13.29  ? 393 SER A CB  1 
ATOM   1394  O OG  . SER A 1 191 ? -11.391 -13.080 46.465 1.00 17.18  ? 393 SER A OG  1 
ATOM   1395  N N   . PHE A 1 192 ? -8.737  -15.215 45.187 1.00 14.12  ? 394 PHE A N   1 
ATOM   1396  C CA  . PHE A 1 192 ? -8.500  -16.637 45.371 1.00 13.07  ? 394 PHE A CA  1 
ATOM   1397  C C   . PHE A 1 192 ? -8.204  -16.902 46.840 1.00 14.33  ? 394 PHE A C   1 
ATOM   1398  O O   . PHE A 1 192 ? -7.346  -16.243 47.431 1.00 14.36  ? 394 PHE A O   1 
ATOM   1399  C CB  . PHE A 1 192 ? -7.346  -17.101 44.482 1.00 13.69  ? 394 PHE A CB  1 
ATOM   1400  C CG  . PHE A 1 192 ? -6.893  -18.498 44.752 1.00 13.14  ? 394 PHE A CG  1 
ATOM   1401  C CD1 . PHE A 1 192 ? -7.632  -19.575 44.317 1.00 13.06  ? 394 PHE A CD1 1 
ATOM   1402  C CD2 . PHE A 1 192 ? -5.709  -18.735 45.418 1.00 13.48  ? 394 PHE A CD2 1 
ATOM   1403  C CE1 . PHE A 1 192 ? -7.213  -20.860 44.560 1.00 12.61  ? 394 PHE A CE1 1 
ATOM   1404  C CE2 . PHE A 1 192 ? -5.285  -20.018 45.661 1.00 12.89  ? 394 PHE A CE2 1 
ATOM   1405  C CZ  . PHE A 1 192 ? -6.037  -21.081 45.232 1.00 12.36  ? 394 PHE A CZ  1 
ATOM   1406  N N   . TYR A 1 193 ? -8.925  -17.851 47.430 1.00 12.49  ? 395 TYR A N   1 
ATOM   1407  C CA  . TYR A 1 193 ? -8.776  -18.195 48.838 1.00 13.23  ? 395 TYR A CA  1 
ATOM   1408  C C   . TYR A 1 193 ? -8.222  -19.604 48.958 1.00 14.88  ? 395 TYR A C   1 
ATOM   1409  O O   . TYR A 1 193 ? -8.780  -20.545 48.385 1.00 14.98  ? 395 TYR A O   1 
ATOM   1410  C CB  . TYR A 1 193 ? -10.111 -18.087 49.575 1.00 12.42  ? 395 TYR A CB  1 
ATOM   1411  C CG  . TYR A 1 193 ? -10.635 -16.680 49.682 1.00 13.62  ? 395 TYR A CG  1 
ATOM   1412  C CD1 . TYR A 1 193 ? -10.290 -15.873 50.753 1.00 14.63  ? 395 TYR A CD1 1 
ATOM   1413  C CD2 . TYR A 1 193 ? -11.466 -16.154 48.709 1.00 14.78  ? 395 TYR A CD2 1 
ATOM   1414  C CE1 . TYR A 1 193 ? -10.765 -14.587 50.853 1.00 16.46  ? 395 TYR A CE1 1 
ATOM   1415  C CE2 . TYR A 1 193 ? -11.943 -14.871 48.802 1.00 17.19  ? 395 TYR A CE2 1 
ATOM   1416  C CZ  . TYR A 1 193 ? -11.589 -14.091 49.875 1.00 17.62  ? 395 TYR A CZ  1 
ATOM   1417  O OH  . TYR A 1 193 ? -12.064 -12.805 49.969 1.00 19.21  ? 395 TYR A OH  1 
ATOM   1418  N N   . CYS A 1 194 ? -7.130  -19.746 49.701 1.00 17.17  ? 396 CYS A N   1 
ATOM   1419  C CA  . CYS A 1 194 ? -6.577  -21.051 50.035 1.00 18.37  ? 396 CYS A CA  1 
ATOM   1420  C C   . CYS A 1 194 ? -6.941  -21.380 51.476 1.00 17.75  ? 396 CYS A C   1 
ATOM   1421  O O   . CYS A 1 194 ? -6.426  -20.756 52.409 1.00 18.39  ? 396 CYS A O   1 
ATOM   1422  C CB  . CYS A 1 194 ? -5.063  -21.071 49.844 1.00 17.64  ? 396 CYS A CB  1 
ATOM   1423  S SG  . CYS A 1 194 ? -4.299  -22.662 50.199 1.00 25.84  ? 396 CYS A SG  1 
ATOM   1424  N N   . LEU A 1 195 ? -7.821  -22.361 51.656 1.00 21.06  ? 397 LEU A N   1 
ATOM   1425  C CA  . LEU A 1 195 ? -8.303  -22.703 52.986 1.00 21.38  ? 397 LEU A CA  1 
ATOM   1426  C C   . LEU A 1 195 ? -7.217  -23.296 53.871 1.00 22.95  ? 397 LEU A C   1 
ATOM   1427  O O   . LEU A 1 195 ? -7.393  -23.346 55.092 1.00 23.28  ? 397 LEU A O   1 
ATOM   1428  C CB  . LEU A 1 195 ? -9.481  -23.674 52.887 1.00 22.61  ? 397 LEU A CB  1 
ATOM   1429  C CG  . LEU A 1 195 ? -10.874 -23.078 52.675 1.00 20.72  ? 397 LEU A CG  1 
ATOM   1430  C CD1 . LEU A 1 195 ? -10.999 -22.387 51.328 1.00 18.65  ? 397 LEU A CD1 1 
ATOM   1431  C CD2 . LEU A 1 195 ? -11.922 -24.158 52.813 1.00 20.38  ? 397 LEU A CD2 1 
ATOM   1432  N N   . GLU A 1 196 ? -6.101  -23.742 53.292 1.00 23.18  ? 398 GLU A N   1 
ATOM   1433  C CA  . GLU A 1 196 ? -4.980  -24.217 54.093 1.00 24.64  ? 398 GLU A CA  1 
ATOM   1434  C C   . GLU A 1 196 ? -4.276  -23.092 54.833 1.00 24.26  ? 398 GLU A C   1 
ATOM   1435  O O   . GLU A 1 196 ? -3.442  -23.368 55.701 1.00 24.73  ? 398 GLU A O   1 
ATOM   1436  C CB  . GLU A 1 196 ? -3.965  -24.942 53.212 1.00 20.53  ? 398 GLU A CB  1 
ATOM   1437  C CG  . GLU A 1 196 ? -4.491  -26.180 52.529 1.00 27.52  ? 398 GLU A CG  1 
ATOM   1438  C CD  . GLU A 1 196 ? -5.015  -27.207 53.506 1.00 31.91  ? 398 GLU A CD  1 
ATOM   1439  O OE1 . GLU A 1 196 ? -4.433  -27.345 54.602 1.00 35.55  ? 398 GLU A OE1 1 
ATOM   1440  O OE2 . GLU A 1 196 ? -6.005  -27.888 53.171 1.00 32.82  ? 398 GLU A OE2 1 
ATOM   1441  N N   . TYR A 1 197 ? -4.591  -21.843 54.518 1.00 26.88  ? 399 TYR A N   1 
ATOM   1442  C CA  . TYR A 1 197 ? -3.901  -20.690 55.071 1.00 26.63  ? 399 TYR A CA  1 
ATOM   1443  C C   . TYR A 1 197 ? -4.548  -20.203 56.363 1.00 25.30  ? 399 TYR A C   1 
ATOM   1444  O O   . TYR A 1 197 ? -4.159  -19.157 56.890 1.00 24.89  ? 399 TYR A O   1 
ATOM   1445  C CB  . TYR A 1 197 ? -3.841  -19.587 54.006 1.00 20.72  ? 399 TYR A CB  1 
ATOM   1446  C CG  . TYR A 1 197 ? -3.081  -18.340 54.384 1.00 24.10  ? 399 TYR A CG  1 
ATOM   1447  C CD1 . TYR A 1 197 ? -1.705  -18.368 54.540 1.00 24.84  ? 399 TYR A CD1 1 
ATOM   1448  C CD2 . TYR A 1 197 ? -3.728  -17.123 54.514 1.00 25.19  ? 399 TYR A CD2 1 
ATOM   1449  C CE1 . TYR A 1 197 ? -1.003  -17.234 54.865 1.00 26.67  ? 399 TYR A CE1 1 
ATOM   1450  C CE2 . TYR A 1 197 ? -3.032  -15.981 54.833 1.00 27.34  ? 399 TYR A CE2 1 
ATOM   1451  C CZ  . TYR A 1 197 ? -1.671  -16.042 55.007 1.00 28.56  ? 399 TYR A CZ  1 
ATOM   1452  O OH  . TYR A 1 197 ? -0.974  -14.902 55.326 1.00 31.90  ? 399 TYR A OH  1 
ATOM   1453  N N   . PHE A 1 198 ? -5.541  -20.936 56.875 1.00 27.05  ? 400 PHE A N   1 
ATOM   1454  C CA  . PHE A 1 198 ? -6.303  -20.889 58.113 1.00 26.14  ? 400 PHE A CA  1 
ATOM   1455  C C   . PHE A 1 198 ? -5.750  -21.881 59.129 1.00 25.92  ? 400 PHE A C   1 
ATOM   1456  O O   . PHE A 1 198 ? -5.490  -23.040 58.796 1.00 27.45  ? 400 PHE A O   1 
ATOM   1457  C CB  . PHE A 1 198 ? -7.766  -21.211 57.847 1.00 24.75  ? 400 PHE A CB  1 
ATOM   1458  C CG  . PHE A 1 198 ? -8.467  -20.186 57.020 1.00 24.22  ? 400 PHE A CG  1 
ATOM   1459  C CD1 . PHE A 1 198 ? -9.094  -19.111 57.617 1.00 23.94  ? 400 PHE A CD1 1 
ATOM   1460  C CD2 . PHE A 1 198 ? -8.486  -20.284 55.644 1.00 23.92  ? 400 PHE A CD2 1 
ATOM   1461  C CE1 . PHE A 1 198 ? -9.737  -18.164 56.858 1.00 24.99  ? 400 PHE A CE1 1 
ATOM   1462  C CE2 . PHE A 1 198 ? -9.123  -19.338 54.882 1.00 24.77  ? 400 PHE A CE2 1 
ATOM   1463  C CZ  . PHE A 1 198 ? -9.749  -18.277 55.489 1.00 25.73  ? 400 PHE A CZ  1 
ATOM   1464  N N   . PRO A 1 199 ? -5.549  -21.454 60.373 1.00 31.73  ? 401 PRO A N   1 
ATOM   1465  C CA  . PRO A 1 199 ? -5.211  -22.415 61.427 1.00 31.25  ? 401 PRO A CA  1 
ATOM   1466  C C   . PRO A 1 199 ? -6.385  -23.336 61.724 1.00 30.57  ? 401 PRO A C   1 
ATOM   1467  O O   . PRO A 1 199 ? -7.526  -22.894 61.867 1.00 30.34  ? 401 PRO A O   1 
ATOM   1468  C CB  . PRO A 1 199 ? -4.873  -21.522 62.625 1.00 31.20  ? 401 PRO A CB  1 
ATOM   1469  C CG  . PRO A 1 199 ? -5.630  -20.270 62.373 1.00 31.40  ? 401 PRO A CG  1 
ATOM   1470  C CD  . PRO A 1 199 ? -5.624  -20.077 60.885 1.00 32.72  ? 401 PRO A CD  1 
ATOM   1471  N N   . SER A 1 200 ? -6.091  -24.631 61.815 1.00 33.87  ? 402 SER A N   1 
ATOM   1472  C CA  . SER A 1 200 ? -7.116  -25.650 61.975 1.00 33.18  ? 402 SER A CA  1 
ATOM   1473  C C   . SER A 1 200 ? -6.645  -26.698 62.971 1.00 32.15  ? 402 SER A C   1 
ATOM   1474  O O   . SER A 1 200 ? -5.473  -26.746 63.349 1.00 32.39  ? 402 SER A O   1 
ATOM   1475  C CB  . SER A 1 200 ? -7.460  -26.312 60.637 1.00 31.20  ? 402 SER A CB  1 
ATOM   1476  O OG  . SER A 1 200 ? -6.345  -26.996 60.103 1.00 32.81  ? 402 SER A OG  1 
ATOM   1477  N N   . GLN A 1 201 ? -7.582  -27.537 63.399 1.00 35.55  ? 403 GLN A N   1 
ATOM   1478  C CA  . GLN A 1 201 ? -7.284  -28.629 64.313 1.00 35.32  ? 403 GLN A CA  1 
ATOM   1479  C C   . GLN A 1 201 ? -7.208  -29.941 63.546 1.00 35.15  ? 403 GLN A C   1 
ATOM   1480  O O   . GLN A 1 201 ? -7.951  -30.155 62.585 1.00 35.59  ? 403 GLN A O   1 
ATOM   1481  C CB  . GLN A 1 201 ? -8.345  -28.715 65.412 1.00 37.73  ? 403 GLN A CB  1 
ATOM   1482  C CG  . GLN A 1 201 ? -8.068  -29.765 66.469 1.00 43.49  ? 403 GLN A CG  1 
ATOM   1483  C CD  . GLN A 1 201 ? -9.039  -29.696 67.628 1.00 45.92  ? 403 GLN A CD  1 
ATOM   1484  O OE1 . GLN A 1 201 ? -9.849  -28.775 67.718 1.00 47.09  ? 403 GLN A OE1 1 
ATOM   1485  N NE2 . GLN A 1 201 ? -8.968  -30.676 68.520 1.00 46.88  ? 403 GLN A NE2 1 
ATOM   1486  N N   . MET A 1 202 ? -6.293  -30.810 63.963 1.00 40.24  ? 404 MET A N   1 
ATOM   1487  C CA  . MET A 1 202 ? -6.069  -32.093 63.312 1.00 39.87  ? 404 MET A CA  1 
ATOM   1488  C C   . MET A 1 202 ? -6.439  -33.213 64.275 1.00 39.65  ? 404 MET A C   1 
ATOM   1489  O O   . MET A 1 202 ? -5.961  -33.241 65.413 1.00 41.07  ? 404 MET A O   1 
ATOM   1490  C CB  . MET A 1 202 ? -4.615  -32.223 62.856 1.00 35.00  ? 404 MET A CB  1 
ATOM   1491  C CG  . MET A 1 202 ? -4.224  -31.160 61.843 1.00 37.24  ? 404 MET A CG  1 
ATOM   1492  S SD  . MET A 1 202 ? -2.520  -31.226 61.266 1.00 40.90  ? 404 MET A SD  1 
ATOM   1493  C CE  . MET A 1 202 ? -2.602  -32.597 60.128 1.00 39.43  ? 404 MET A CE  1 
ATOM   1494  N N   . LEU A 1 203 ? -7.292  -34.128 63.818 1.00 42.19  ? 405 LEU A N   1 
ATOM   1495  C CA  . LEU A 1 203 ? -7.876  -35.158 64.669 1.00 42.09  ? 405 LEU A CA  1 
ATOM   1496  C C   . LEU A 1 203 ? -7.447  -36.533 64.183 1.00 42.38  ? 405 LEU A C   1 
ATOM   1497  O O   . LEU A 1 203 ? -7.632  -36.866 63.008 1.00 42.65  ? 405 LEU A O   1 
ATOM   1498  C CB  . LEU A 1 203 ? -9.403  -35.067 64.678 1.00 42.04  ? 405 LEU A CB  1 
ATOM   1499  C CG  . LEU A 1 203 ? -10.092 -34.062 65.599 1.00 39.96  ? 405 LEU A CG  1 
ATOM   1500  C CD1 . LEU A 1 203 ? -9.818  -32.642 65.156 1.00 38.00  ? 405 LEU A CD1 1 
ATOM   1501  C CD2 . LEU A 1 203 ? -11.580 -34.327 65.636 1.00 39.31  ? 405 LEU A CD2 1 
ATOM   1502  N N   . ARG A 1 204 ? -6.877  -37.326 65.086 1.00 48.35  ? 406 ARG A N   1 
ATOM   1503  C CA  . ARG A 1 204 ? -6.688  -38.747 64.853 1.00 50.13  ? 406 ARG A CA  1 
ATOM   1504  C C   . ARG A 1 204 ? -7.876  -39.528 65.411 1.00 51.62  ? 406 ARG A C   1 
ATOM   1505  O O   . ARG A 1 204 ? -8.907  -38.965 65.782 1.00 51.58  ? 406 ARG A O   1 
ATOM   1506  C CB  . ARG A 1 204 ? -5.372  -39.229 65.458 1.00 48.54  ? 406 ARG A CB  1 
ATOM   1507  C CG  . ARG A 1 204 ? -4.152  -38.790 64.682 1.00 48.37  ? 406 ARG A CG  1 
ATOM   1508  C CD  . ARG A 1 204 ? -2.884  -39.373 65.266 1.00 48.11  ? 406 ARG A CD  1 
ATOM   1509  N NE  . ARG A 1 204 ? -1.714  -39.009 64.476 1.00 52.22  ? 406 ARG A NE  1 
ATOM   1510  C CZ  . ARG A 1 204 ? -0.467  -39.318 64.808 1.00 52.87  ? 406 ARG A CZ  1 
ATOM   1511  N NH1 . ARG A 1 204 ? -0.224  -39.990 65.922 1.00 53.61  ? 406 ARG A NH1 1 
ATOM   1512  N NH2 . ARG A 1 204 ? 0.538   -38.953 64.026 1.00 53.04  ? 406 ARG A NH2 1 
ATOM   1513  N N   . THR A 1 205 ? -7.729  -40.854 65.463 1.00 51.86  ? 407 THR A N   1 
ATOM   1514  C CA  . THR A 1 205 ? -8.825  -41.714 65.890 1.00 53.41  ? 407 THR A CA  1 
ATOM   1515  C C   . THR A 1 205 ? -9.230  -41.477 67.338 1.00 54.47  ? 407 THR A C   1 
ATOM   1516  O O   . THR A 1 205 ? -10.335 -41.867 67.727 1.00 59.74  ? 407 THR A O   1 
ATOM   1517  C CB  . THR A 1 205 ? -8.449  -43.183 65.688 1.00 57.60  ? 407 THR A CB  1 
ATOM   1518  O OG1 . THR A 1 205 ? -9.587  -44.010 65.954 1.00 60.92  ? 407 THR A OG1 1 
ATOM   1519  C CG2 . THR A 1 205 ? -7.319  -43.580 66.615 1.00 56.47  ? 407 THR A CG2 1 
ATOM   1520  N N   . GLY A 1 206 ? -8.377  -40.844 68.140 1.00 55.43  ? 408 GLY A N   1 
ATOM   1521  C CA  . GLY A 1 206 ? -8.719  -40.561 69.518 1.00 55.36  ? 408 GLY A CA  1 
ATOM   1522  C C   . GLY A 1 206 ? -9.025  -39.117 69.833 1.00 53.94  ? 408 GLY A C   1 
ATOM   1523  O O   . GLY A 1 206 ? -9.122  -38.760 71.011 1.00 54.82  ? 408 GLY A O   1 
ATOM   1524  N N   . ASN A 1 207 ? -9.184  -38.273 68.819 1.00 49.91  ? 409 ASN A N   1 
ATOM   1525  C CA  . ASN A 1 207 ? -9.407  -36.856 69.052 1.00 48.81  ? 409 ASN A CA  1 
ATOM   1526  C C   . ASN A 1 207 ? -10.818 -36.450 68.641 1.00 48.31  ? 409 ASN A C   1 
ATOM   1527  O O   . ASN A 1 207 ? -11.397 -36.979 67.690 1.00 48.56  ? 409 ASN A O   1 
ATOM   1528  C CB  . ASN A 1 207 ? -8.385  -36.017 68.287 1.00 48.27  ? 409 ASN A CB  1 
ATOM   1529  C CG  . ASN A 1 207 ? -6.968  -36.247 68.763 1.00 48.40  ? 409 ASN A CG  1 
ATOM   1530  O OD1 . ASN A 1 207 ? -6.069  -36.503 67.966 1.00 49.52  ? 409 ASN A OD1 1 
ATOM   1531  N ND2 . ASN A 1 207 ? -6.759  -36.146 70.068 1.00 49.18  ? 409 ASN A ND2 1 
ATOM   1532  N N   . ASN A 1 208 ? -11.364 -35.486 69.377 1.00 47.46  ? 410 ASN A N   1 
ATOM   1533  C CA  . ASN A 1 208 ? -12.691 -34.945 69.128 1.00 47.13  ? 410 ASN A CA  1 
ATOM   1534  C C   . ASN A 1 208 ? -12.605 -33.434 68.951 1.00 47.23  ? 410 ASN A C   1 
ATOM   1535  O O   . ASN A 1 208 ? -11.611 -32.798 69.309 1.00 47.47  ? 410 ASN A O   1 
ATOM   1536  C CB  . ASN A 1 208 ? -13.668 -35.321 70.256 1.00 50.98  ? 410 ASN A CB  1 
ATOM   1537  C CG  . ASN A 1 208 ? -13.185 -34.884 71.631 1.00 51.95  ? 410 ASN A CG  1 
ATOM   1538  O OD1 . ASN A 1 208 ? -12.510 -33.869 71.781 1.00 54.97  ? 410 ASN A OD1 1 
ATOM   1539  N ND2 . ASN A 1 208 ? -13.542 -35.658 72.647 1.00 52.45  ? 410 ASN A ND2 1 
ATOM   1540  N N   . PHE A 1 209 ? -13.665 -32.861 68.386 1.00 42.81  ? 411 PHE A N   1 
ATOM   1541  C CA  . PHE A 1 209 ? -13.731 -31.434 68.114 1.00 43.67  ? 411 PHE A CA  1 
ATOM   1542  C C   . PHE A 1 209 ? -15.083 -30.898 68.546 1.00 44.11  ? 411 PHE A C   1 
ATOM   1543  O O   . PHE A 1 209 ? -16.107 -31.558 68.356 1.00 44.64  ? 411 PHE A O   1 
ATOM   1544  C CB  . PHE A 1 209 ? -13.514 -31.135 66.628 1.00 40.99  ? 411 PHE A CB  1 
ATOM   1545  C CG  . PHE A 1 209 ? -13.682 -29.685 66.269 1.00 41.69  ? 411 PHE A CG  1 
ATOM   1546  C CD1 . PHE A 1 209 ? -12.663 -28.780 66.498 1.00 42.21  ? 411 PHE A CD1 1 
ATOM   1547  C CD2 . PHE A 1 209 ? -14.858 -29.229 65.702 1.00 41.37  ? 411 PHE A CD2 1 
ATOM   1548  C CE1 . PHE A 1 209 ? -12.815 -27.451 66.170 1.00 41.40  ? 411 PHE A CE1 1 
ATOM   1549  C CE2 . PHE A 1 209 ? -15.012 -27.902 65.372 1.00 41.93  ? 411 PHE A CE2 1 
ATOM   1550  C CZ  . PHE A 1 209 ? -13.990 -27.013 65.607 1.00 41.31  ? 411 PHE A CZ  1 
ATOM   1551  N N   . GLN A 1 210 ? -15.086 -29.699 69.121 1.00 42.68  ? 412 GLN A N   1 
ATOM   1552  C CA  . GLN A 1 210 ? -16.337 -29.058 69.492 1.00 45.27  ? 412 GLN A CA  1 
ATOM   1553  C C   . GLN A 1 210 ? -16.147 -27.551 69.526 1.00 44.39  ? 412 GLN A C   1 
ATOM   1554  O O   . GLN A 1 210 ? -15.032 -27.049 69.683 1.00 45.31  ? 412 GLN A O   1 
ATOM   1555  C CB  . GLN A 1 210 ? -16.848 -29.552 70.850 1.00 43.23  ? 412 GLN A CB  1 
ATOM   1556  C CG  . GLN A 1 210 ? -15.948 -29.201 72.013 1.00 51.79  ? 412 GLN A CG  1 
ATOM   1557  C CD  . GLN A 1 210 ? -16.517 -29.659 73.336 1.00 59.43  ? 412 GLN A CD  1 
ATOM   1558  O OE1 . GLN A 1 210 ? -17.384 -30.530 73.381 1.00 62.29  ? 412 GLN A OE1 1 
ATOM   1559  N NE2 . GLN A 1 210 ? -16.037 -29.068 74.425 1.00 60.83  ? 412 GLN A NE2 1 
ATOM   1560  N N   . PHE A 1 211 ? -17.257 -26.834 69.375 1.00 44.12  ? 413 PHE A N   1 
ATOM   1561  C CA  . PHE A 1 211 ? -17.266 -25.396 69.594 1.00 43.24  ? 413 PHE A CA  1 
ATOM   1562  C C   . PHE A 1 211 ? -18.693 -24.979 69.904 1.00 42.89  ? 413 PHE A C   1 
ATOM   1563  O O   . PHE A 1 211 ? -19.649 -25.682 69.569 1.00 42.04  ? 413 PHE A O   1 
ATOM   1564  C CB  . PHE A 1 211 ? -16.726 -24.625 68.384 1.00 39.53  ? 413 PHE A CB  1 
ATOM   1565  C CG  . PHE A 1 211 ? -17.617 -24.681 67.181 1.00 40.11  ? 413 PHE A CG  1 
ATOM   1566  C CD1 . PHE A 1 211 ? -18.559 -23.691 66.960 1.00 40.94  ? 413 PHE A CD1 1 
ATOM   1567  C CD2 . PHE A 1 211 ? -17.527 -25.723 66.279 1.00 40.98  ? 413 PHE A CD2 1 
ATOM   1568  C CE1 . PHE A 1 211 ? -19.385 -23.734 65.863 1.00 40.81  ? 413 PHE A CE1 1 
ATOM   1569  C CE2 . PHE A 1 211 ? -18.354 -25.772 65.181 1.00 41.85  ? 413 PHE A CE2 1 
ATOM   1570  C CZ  . PHE A 1 211 ? -19.283 -24.775 64.971 1.00 41.80  ? 413 PHE A CZ  1 
ATOM   1571  N N   . SER A 1 212 ? -18.826 -23.819 70.535 1.00 42.46  ? 414 SER A N   1 
ATOM   1572  C CA  . SER A 1 212 ? -20.125 -23.270 70.885 1.00 42.16  ? 414 SER A CA  1 
ATOM   1573  C C   . SER A 1 212 ? -20.333 -21.961 70.139 1.00 41.78  ? 414 SER A C   1 
ATOM   1574  O O   . SER A 1 212 ? -19.379 -21.301 69.721 1.00 41.89  ? 414 SER A O   1 
ATOM   1575  C CB  . SER A 1 212 ? -20.256 -23.055 72.399 1.00 46.45  ? 414 SER A CB  1 
ATOM   1576  O OG  . SER A 1 212 ? -19.310 -22.110 72.865 1.00 51.27  ? 414 SER A OG  1 
ATOM   1577  N N   . TYR A 1 213 ? -21.599 -21.594 69.965 1.00 39.86  ? 415 TYR A N   1 
ATOM   1578  C CA  . TYR A 1 213 ? -21.963 -20.410 69.205 1.00 40.16  ? 415 TYR A CA  1 
ATOM   1579  C C   . TYR A 1 213 ? -23.160 -19.729 69.848 1.00 42.07  ? 415 TYR A C   1 
ATOM   1580  O O   . TYR A 1 213 ? -24.041 -20.384 70.408 1.00 41.99  ? 415 TYR A O   1 
ATOM   1581  C CB  . TYR A 1 213 ? -22.276 -20.757 67.746 1.00 35.28  ? 415 TYR A CB  1 
ATOM   1582  C CG  . TYR A 1 213 ? -22.848 -19.607 66.954 1.00 35.61  ? 415 TYR A CG  1 
ATOM   1583  C CD1 . TYR A 1 213 ? -22.040 -18.573 66.512 1.00 33.96  ? 415 TYR A CD1 1 
ATOM   1584  C CD2 . TYR A 1 213 ? -24.199 -19.560 66.645 1.00 36.55  ? 415 TYR A CD2 1 
ATOM   1585  C CE1 . TYR A 1 213 ? -22.561 -17.526 65.789 1.00 35.74  ? 415 TYR A CE1 1 
ATOM   1586  C CE2 . TYR A 1 213 ? -24.728 -18.518 65.922 1.00 36.49  ? 415 TYR A CE2 1 
ATOM   1587  C CZ  . TYR A 1 213 ? -23.906 -17.505 65.498 1.00 36.94  ? 415 TYR A CZ  1 
ATOM   1588  O OH  . TYR A 1 213 ? -24.431 -16.464 64.778 1.00 39.36  ? 415 TYR A OH  1 
ATOM   1589  N N   . GLU A 1 214 ? -23.178 -18.403 69.758 1.00 39.03  ? 416 GLU A N   1 
ATOM   1590  C CA  . GLU A 1 214 ? -24.244 -17.578 70.309 1.00 41.65  ? 416 GLU A CA  1 
ATOM   1591  C C   . GLU A 1 214 ? -24.976 -16.885 69.168 1.00 40.38  ? 416 GLU A C   1 
ATOM   1592  O O   . GLU A 1 214 ? -24.417 -15.995 68.519 1.00 41.04  ? 416 GLU A O   1 
ATOM   1593  C CB  . GLU A 1 214 ? -23.677 -16.543 71.280 1.00 40.87  ? 416 GLU A CB  1 
ATOM   1594  C CG  . GLU A 1 214 ? -24.723 -15.695 71.982 1.00 52.47  ? 416 GLU A CG  1 
ATOM   1595  C CD  . GLU A 1 214 ? -25.514 -16.481 72.999 1.00 58.80  ? 416 GLU A CD  1 
ATOM   1596  O OE1 . GLU A 1 214 ? -25.065 -17.584 73.366 1.00 60.62  ? 416 GLU A OE1 1 
ATOM   1597  O OE2 . GLU A 1 214 ? -26.582 -15.999 73.430 1.00 62.95  ? 416 GLU A OE2 1 
ATOM   1598  N N   . PHE A 1 215 ? -26.219 -17.291 68.924 1.00 41.89  ? 417 PHE A N   1 
ATOM   1599  C CA  . PHE A 1 215 ? -27.050 -16.598 67.948 1.00 41.82  ? 417 PHE A CA  1 
ATOM   1600  C C   . PHE A 1 215 ? -27.282 -15.156 68.376 1.00 44.58  ? 417 PHE A C   1 
ATOM   1601  O O   . PHE A 1 215 ? -27.697 -14.887 69.506 1.00 44.15  ? 417 PHE A O   1 
ATOM   1602  C CB  . PHE A 1 215 ? -28.393 -17.310 67.789 1.00 42.51  ? 417 PHE A CB  1 
ATOM   1603  C CG  . PHE A 1 215 ? -28.306 -18.630 67.088 1.00 39.51  ? 417 PHE A CG  1 
ATOM   1604  C CD1 . PHE A 1 215 ? -28.457 -18.706 65.717 1.00 37.95  ? 417 PHE A CD1 1 
ATOM   1605  C CD2 . PHE A 1 215 ? -28.056 -19.791 67.794 1.00 38.71  ? 417 PHE A CD2 1 
ATOM   1606  C CE1 . PHE A 1 215 ? -28.381 -19.915 65.066 1.00 36.87  ? 417 PHE A CE1 1 
ATOM   1607  C CE2 . PHE A 1 215 ? -27.972 -21.003 67.145 1.00 37.17  ? 417 PHE A CE2 1 
ATOM   1608  C CZ  . PHE A 1 215 ? -28.133 -21.065 65.779 1.00 36.98  ? 417 PHE A CZ  1 
ATOM   1609  N N   . GLU A 1 216 ? -27.011 -14.224 67.469 1.00 38.97  ? 418 GLU A N   1 
ATOM   1610  C CA  . GLU A 1 216 ? -27.314 -12.834 67.761 1.00 43.05  ? 418 GLU A CA  1 
ATOM   1611  C C   . GLU A 1 216 ? -28.824 -12.631 67.806 1.00 43.10  ? 418 GLU A C   1 
ATOM   1612  O O   . GLU A 1 216 ? -29.597 -13.400 67.229 1.00 42.69  ? 418 GLU A O   1 
ATOM   1613  C CB  . GLU A 1 216 ? -26.677 -11.904 66.730 1.00 31.88  ? 418 GLU A CB  1 
ATOM   1614  C CG  . GLU A 1 216 ? -27.177 -12.088 65.313 1.00 39.13  ? 418 GLU A CG  1 
ATOM   1615  C CD  . GLU A 1 216 ? -26.435 -11.211 64.327 1.00 44.18  ? 418 GLU A CD  1 
ATOM   1616  O OE1 . GLU A 1 216 ? -25.784 -10.240 64.766 1.00 47.55  ? 418 GLU A OE1 1 
ATOM   1617  O OE2 . GLU A 1 216 ? -26.496 -11.492 63.115 1.00 45.94  ? 418 GLU A OE2 1 
ATOM   1618  N N   . ASN A 1 217 ? -29.239 -11.582 68.511 1.00 44.45  ? 419 ASN A N   1 
ATOM   1619  C CA  . ASN A 1 217 ? -30.654 -11.384 68.787 1.00 45.62  ? 419 ASN A CA  1 
ATOM   1620  C C   . ASN A 1 217 ? -31.438 -11.180 67.498 1.00 44.39  ? 419 ASN A C   1 
ATOM   1621  O O   . ASN A 1 217 ? -31.125 -10.299 66.694 1.00 44.94  ? 419 ASN A O   1 
ATOM   1622  C CB  . ASN A 1 217 ? -30.846 -10.189 69.718 1.00 43.96  ? 419 ASN A CB  1 
ATOM   1623  C CG  . ASN A 1 217 ? -32.260 -10.094 70.258 1.00 49.36  ? 419 ASN A CG  1 
ATOM   1624  O OD1 . ASN A 1 217 ? -32.940 -11.105 70.431 1.00 52.34  ? 419 ASN A OD1 1 
ATOM   1625  N ND2 . ASN A 1 217 ? -32.710 -8.874  70.525 1.00 51.70  ? 419 ASN A ND2 1 
ATOM   1626  N N   . VAL A 1 218 ? -32.462 -12.005 67.308 1.00 48.17  ? 420 VAL A N   1 
ATOM   1627  C CA  . VAL A 1 218 ? -33.363 -11.892 66.164 1.00 46.64  ? 420 VAL A CA  1 
ATOM   1628  C C   . VAL A 1 218 ? -34.789 -11.877 66.694 1.00 45.28  ? 420 VAL A C   1 
ATOM   1629  O O   . VAL A 1 218 ? -35.054 -12.332 67.817 1.00 45.28  ? 420 VAL A O   1 
ATOM   1630  C CB  . VAL A 1 218 ? -33.157 -13.045 65.154 1.00 40.33  ? 420 VAL A CB  1 
ATOM   1631  C CG1 . VAL A 1 218 ? -31.768 -12.988 64.552 1.00 43.30  ? 420 VAL A CG1 1 
ATOM   1632  C CG2 . VAL A 1 218 ? -33.398 -14.383 65.821 1.00 41.47  ? 420 VAL A CG2 1 
ATOM   1633  N N   . PRO A 1 219 ? -35.729 -11.338 65.925 1.00 46.02  ? 421 PRO A N   1 
ATOM   1634  C CA  . PRO A 1 219 ? -37.132 -11.417 66.334 1.00 44.74  ? 421 PRO A CA  1 
ATOM   1635  C C   . PRO A 1 219 ? -37.639 -12.845 66.245 1.00 44.00  ? 421 PRO A C   1 
ATOM   1636  O O   . PRO A 1 219 ? -37.169 -13.652 65.441 1.00 44.61  ? 421 PRO A O   1 
ATOM   1637  C CB  . PRO A 1 219 ? -37.847 -10.509 65.328 1.00 44.26  ? 421 PRO A CB  1 
ATOM   1638  C CG  . PRO A 1 219 ? -36.974 -10.546 64.124 1.00 44.83  ? 421 PRO A CG  1 
ATOM   1639  C CD  . PRO A 1 219 ? -35.572 -10.604 64.657 1.00 44.54  ? 421 PRO A CD  1 
ATOM   1640  N N   . PHE A 1 220 ? -38.604 -13.157 67.105 1.00 45.92  ? 422 PHE A N   1 
ATOM   1641  C CA  . PHE A 1 220 ? -39.283 -14.439 67.007 1.00 43.94  ? 422 PHE A CA  1 
ATOM   1642  C C   . PHE A 1 220 ? -39.934 -14.573 65.640 1.00 43.61  ? 422 PHE A C   1 
ATOM   1643  O O   . PHE A 1 220 ? -40.640 -13.670 65.184 1.00 43.55  ? 422 PHE A O   1 
ATOM   1644  C CB  . PHE A 1 220 ? -40.352 -14.575 68.091 1.00 45.90  ? 422 PHE A CB  1 
ATOM   1645  C CG  . PHE A 1 220 ? -39.810 -14.639 69.484 1.00 47.55  ? 422 PHE A CG  1 
ATOM   1646  C CD1 . PHE A 1 220 ? -39.401 -15.841 70.027 1.00 47.51  ? 422 PHE A CD1 1 
ATOM   1647  C CD2 . PHE A 1 220 ? -39.725 -13.499 70.259 1.00 47.58  ? 422 PHE A CD2 1 
ATOM   1648  C CE1 . PHE A 1 220 ? -38.907 -15.904 71.313 1.00 47.35  ? 422 PHE A CE1 1 
ATOM   1649  C CE2 . PHE A 1 220 ? -39.234 -13.555 71.547 1.00 46.74  ? 422 PHE A CE2 1 
ATOM   1650  C CZ  . PHE A 1 220 ? -38.825 -14.759 72.075 1.00 47.00  ? 422 PHE A CZ  1 
ATOM   1651  N N   . HIS A 1 221 ? -39.736 -15.713 64.996 1.00 43.55  ? 423 HIS A N   1 
ATOM   1652  C CA  . HIS A 1 221 ? -40.388 -15.942 63.724 1.00 43.69  ? 423 HIS A CA  1 
ATOM   1653  C C   . HIS A 1 221 ? -41.854 -16.151 64.048 1.00 44.38  ? 423 HIS A C   1 
ATOM   1654  O O   . HIS A 1 221 ? -42.199 -17.071 64.780 1.00 44.56  ? 423 HIS A O   1 
ATOM   1655  C CB  . HIS A 1 221 ? -39.858 -17.192 63.043 1.00 42.73  ? 423 HIS A CB  1 
ATOM   1656  C CG  . HIS A 1 221 ? -40.805 -17.754 62.035 1.00 44.39  ? 423 HIS A CG  1 
ATOM   1657  N ND1 . HIS A 1 221 ? -40.911 -17.256 60.756 1.00 45.49  ? 423 HIS A ND1 1 
ATOM   1658  C CD2 . HIS A 1 221 ? -41.711 -18.754 62.126 1.00 44.72  ? 423 HIS A CD2 1 
ATOM   1659  C CE1 . HIS A 1 221 ? -41.833 -17.934 60.098 1.00 46.11  ? 423 HIS A CE1 1 
ATOM   1660  N NE2 . HIS A 1 221 ? -42.337 -18.846 60.908 1.00 45.96  ? 423 HIS A NE2 1 
ATOM   1661  N N   . SER A 1 222 ? -42.721 -15.300 63.519 1.00 44.18  ? 424 SER A N   1 
ATOM   1662  C CA  . SER A 1 222 ? -44.137 -15.431 63.804 1.00 44.50  ? 424 SER A CA  1 
ATOM   1663  C C   . SER A 1 222 ? -44.644 -16.736 63.238 1.00 43.93  ? 424 SER A C   1 
ATOM   1664  O O   . SER A 1 222 ? -44.425 -17.026 62.072 1.00 44.60  ? 424 SER A O   1 
ATOM   1665  C CB  . SER A 1 222 ? -44.903 -14.285 63.154 1.00 45.52  ? 424 SER A CB  1 
ATOM   1666  O OG  . SER A 1 222 ? -45.122 -14.550 61.782 1.00 49.11  ? 424 SER A OG  1 
ATOM   1667  N N   . SER A 1 223 ? -45.387 -17.488 64.037 1.00 45.86  ? 425 SER A N   1 
ATOM   1668  C CA  . SER A 1 223 ? -45.919 -18.760 63.579 1.00 45.51  ? 425 SER A CA  1 
ATOM   1669  C C   . SER A 1 223 ? -47.397 -18.785 63.881 1.00 44.68  ? 425 SER A C   1 
ATOM   1670  O O   . SER A 1 223 ? -47.868 -19.541 64.722 1.00 45.39  ? 425 SER A O   1 
ATOM   1671  C CB  . SER A 1 223 ? -45.226 -19.921 64.289 1.00 48.14  ? 425 SER A CB  1 
ATOM   1672  O OG  . SER A 1 223 ? -45.319 -19.782 65.693 1.00 50.29  ? 425 SER A OG  1 
ATOM   1673  N N   . TYR A 1 224 ? -48.119 -17.934 63.171 1.00 44.84  ? 426 TYR A N   1 
ATOM   1674  C CA  . TYR A 1 224 ? -49.550 -17.815 63.325 1.00 45.28  ? 426 TYR A CA  1 
ATOM   1675  C C   . TYR A 1 224 ? -50.134 -17.224 62.062 1.00 45.21  ? 426 TYR A C   1 
ATOM   1676  O O   . TYR A 1 224 ? -49.430 -16.615 61.270 1.00 45.58  ? 426 TYR A O   1 
ATOM   1677  C CB  . TYR A 1 224 ? -49.880 -16.916 64.515 1.00 42.62  ? 426 TYR A CB  1 
ATOM   1678  C CG  . TYR A 1 224 ? -49.211 -15.564 64.463 1.00 44.00  ? 426 TYR A CG  1 
ATOM   1679  C CD1 . TYR A 1 224 ? -49.634 -14.593 63.570 1.00 44.46  ? 426 TYR A CD1 1 
ATOM   1680  C CD2 . TYR A 1 224 ? -48.162 -15.256 65.310 1.00 44.80  ? 426 TYR A CD2 1 
ATOM   1681  C CE1 . TYR A 1 224 ? -49.027 -13.357 63.521 1.00 46.78  ? 426 TYR A CE1 1 
ATOM   1682  C CE2 . TYR A 1 224 ? -47.552 -14.023 65.268 1.00 46.80  ? 426 TYR A CE2 1 
ATOM   1683  C CZ  . TYR A 1 224 ? -47.989 -13.078 64.372 1.00 47.67  ? 426 TYR A CZ  1 
ATOM   1684  O OH  . TYR A 1 224 ? -47.378 -11.850 64.330 1.00 48.98  ? 426 TYR A OH  1 
ATOM   1685  N N   . ALA A 1 225 ? -51.428 -17.411 61.878 1.00 43.75  ? 427 ALA A N   1 
ATOM   1686  C CA  . ALA A 1 225 ? -52.120 -16.860 60.738 1.00 43.72  ? 427 ALA A CA  1 
ATOM   1687  C C   . ALA A 1 225 ? -53.096 -15.877 61.344 1.00 44.41  ? 427 ALA A C   1 
ATOM   1688  O O   . ALA A 1 225 ? -53.766 -16.199 62.320 1.00 45.07  ? 427 ALA A O   1 
ATOM   1689  C CB  . ALA A 1 225 ? -52.848 -17.949 59.982 1.00 43.74  ? 427 ALA A CB  1 
ATOM   1690  N N   . HIS A 1 226 ? -53.175 -14.673 60.798 1.00 42.85  ? 428 HIS A N   1 
ATOM   1691  C CA  . HIS A 1 226 ? -54.080 -13.680 61.365 1.00 42.89  ? 428 HIS A CA  1 
ATOM   1692  C C   . HIS A 1 226 ? -55.542 -14.105 61.283 1.00 43.35  ? 428 HIS A C   1 
ATOM   1693  O O   . HIS A 1 226 ? -55.980 -14.696 60.299 1.00 42.06  ? 428 HIS A O   1 
ATOM   1694  C CB  . HIS A 1 226 ? -53.895 -12.316 60.700 1.00 38.61  ? 428 HIS A CB  1 
ATOM   1695  C CG  . HIS A 1 226 ? -52.564 -11.691 60.967 1.00 39.75  ? 428 HIS A CG  1 
ATOM   1696  N ND1 . HIS A 1 226 ? -52.188 -11.249 62.216 1.00 39.33  ? 428 HIS A ND1 1 
ATOM   1697  C CD2 . HIS A 1 226 ? -51.525 -11.422 60.145 1.00 40.37  ? 428 HIS A CD2 1 
ATOM   1698  C CE1 . HIS A 1 226 ? -50.971 -10.744 62.153 1.00 39.75  ? 428 HIS A CE1 1 
ATOM   1699  N NE2 . HIS A 1 226 ? -50.546 -10.837 60.908 1.00 41.38  ? 428 HIS A NE2 1 
ATOM   1700  N N   . SER A 1 227 ? -56.291 -13.799 62.338 1.00 46.61  ? 429 SER A N   1 
ATOM   1701  C CA  . SER A 1 227 ? -57.713 -14.116 62.395 1.00 47.67  ? 429 SER A CA  1 
ATOM   1702  C C   . SER A 1 227 ? -58.552 -12.968 61.831 1.00 47.85  ? 429 SER A C   1 
ATOM   1703  O O   . SER A 1 227 ? -59.771 -13.066 61.734 1.00 48.39  ? 429 SER A O   1 
ATOM   1704  C CB  . SER A 1 227 ? -58.144 -14.449 63.821 1.00 46.36  ? 429 SER A CB  1 
ATOM   1705  O OG  . SER A 1 227 ? -58.288 -13.279 64.596 1.00 50.48  ? 429 SER A OG  1 
ATOM   1706  N N   . GLN A 1 228 ? -57.882 -11.875 61.481 1.00 43.23  ? 430 GLN A N   1 
ATOM   1707  C CA  . GLN A 1 228 ? -58.506 -10.708 60.892 1.00 44.53  ? 430 GLN A CA  1 
ATOM   1708  C C   . GLN A 1 228 ? -57.747 -10.344 59.629 1.00 44.13  ? 430 GLN A C   1 
ATOM   1709  O O   . GLN A 1 228 ? -56.686 -10.891 59.350 1.00 43.99  ? 430 GLN A O   1 
ATOM   1710  C CB  . GLN A 1 228 ? -58.418 -9.525  61.849 1.00 47.43  ? 430 GLN A CB  1 
ATOM   1711  C CG  . GLN A 1 228 ? -59.240 -9.651  63.114 1.00 48.18  ? 430 GLN A CG  1 
ATOM   1712  C CD  . GLN A 1 228 ? -59.361 -8.333  63.843 1.00 48.72  ? 430 GLN A CD  1 
ATOM   1713  O OE1 . GLN A 1 228 ? -58.382 -7.804  64.365 1.00 49.49  ? 430 GLN A OE1 1 
ATOM   1714  N NE2 . GLN A 1 228 ? -60.567 -7.791  63.879 1.00 46.74  ? 430 GLN A NE2 1 
ATOM   1715  N N   . SER A 1 229 ? -58.298 -9.424  58.852 1.00 44.34  ? 431 SER A N   1 
ATOM   1716  C CA  . SER A 1 229 ? -57.625 -8.952  57.655 1.00 44.16  ? 431 SER A CA  1 
ATOM   1717  C C   . SER A 1 229 ? -57.376 -7.455  57.773 1.00 43.90  ? 431 SER A C   1 
ATOM   1718  O O   . SER A 1 229 ? -58.046 -6.756  58.537 1.00 43.19  ? 431 SER A O   1 
ATOM   1719  C CB  . SER A 1 229 ? -58.439 -9.260  56.397 1.00 43.85  ? 431 SER A CB  1 
ATOM   1720  O OG  . SER A 1 229 ? -59.680 -8.587  56.415 1.00 48.33  ? 431 SER A OG  1 
ATOM   1721  N N   . LEU A 1 230 ? -56.388 -6.979  57.012 1.00 43.65  ? 432 LEU A N   1 
ATOM   1722  C CA  . LEU A 1 230 ? -55.927 -5.601  57.145 1.00 43.04  ? 432 LEU A CA  1 
ATOM   1723  C C   . LEU A 1 230 ? -57.047 -4.600  56.904 1.00 43.97  ? 432 LEU A C   1 
ATOM   1724  O O   . LEU A 1 230 ? -57.188 -3.633  57.661 1.00 44.27  ? 432 LEU A O   1 
ATOM   1725  C CB  . LEU A 1 230 ? -54.781 -5.352  56.167 1.00 38.94  ? 432 LEU A CB  1 
ATOM   1726  C CG  . LEU A 1 230 ? -53.955 -4.075  56.289 1.00 39.68  ? 432 LEU A CG  1 
ATOM   1727  C CD1 . LEU A 1 230 ? -53.835 -3.655  57.738 1.00 39.36  ? 432 LEU A CD1 1 
ATOM   1728  C CD2 . LEU A 1 230 ? -52.585 -4.328  55.707 1.00 40.06  ? 432 LEU A CD2 1 
ATOM   1729  N N   . ASP A 1 231 ? -57.848 -4.810  55.868 1.00 46.53  ? 433 ASP A N   1 
ATOM   1730  C CA  . ASP A 1 231 ? -58.908 -3.883  55.500 1.00 48.60  ? 433 ASP A CA  1 
ATOM   1731  C C   . ASP A 1 231 ? -60.165 -4.025  56.352 1.00 47.92  ? 433 ASP A C   1 
ATOM   1732  O O   . ASP A 1 231 ? -60.980 -3.098  56.383 1.00 48.99  ? 433 ASP A O   1 
ATOM   1733  C CB  . ASP A 1 231 ? -59.251 -4.062  54.019 1.00 44.57  ? 433 ASP A CB  1 
ATOM   1734  C CG  . ASP A 1 231 ? -59.587 -5.494  53.673 1.00 48.80  ? 433 ASP A CG  1 
ATOM   1735  O OD1 . ASP A 1 231 ? -59.414 -6.369  54.545 1.00 50.85  ? 433 ASP A OD1 1 
ATOM   1736  O OD2 . ASP A 1 231 ? -60.020 -5.749  52.531 1.00 52.24  ? 433 ASP A OD2 1 
ATOM   1737  N N   . ARG A 1 232 ? -60.350 -5.153  57.034 1.00 49.58  ? 434 ARG A N   1 
ATOM   1738  C CA  . ARG A 1 232 ? -61.530 -5.398  57.854 1.00 47.92  ? 434 ARG A CA  1 
ATOM   1739  C C   . ARG A 1 232 ? -61.328 -5.087  59.334 1.00 47.64  ? 434 ARG A C   1 
ATOM   1740  O O   . ARG A 1 232 ? -62.194 -5.428  60.145 1.00 47.48  ? 434 ARG A O   1 
ATOM   1741  C CB  . ARG A 1 232 ? -62.014 -6.835  57.669 1.00 48.91  ? 434 ARG A CB  1 
ATOM   1742  C CG  . ARG A 1 232 ? -62.554 -7.091  56.277 1.00 50.95  ? 434 ARG A CG  1 
ATOM   1743  C CD  . ARG A 1 232 ? -63.890 -6.381  56.100 1.00 49.56  ? 434 ARG A CD  1 
ATOM   1744  N NE  . ARG A 1 232 ? -64.445 -6.552  54.761 1.00 49.48  ? 434 ARG A NE  1 
ATOM   1745  C CZ  . ARG A 1 232 ? -64.266 -5.690  53.766 1.00 49.44  ? 434 ARG A CZ  1 
ATOM   1746  N NH1 . ARG A 1 232 ? -63.556 -4.590  53.960 1.00 48.32  ? 434 ARG A NH1 1 
ATOM   1747  N NH2 . ARG A 1 232 ? -64.805 -5.923  52.578 1.00 51.49  ? 434 ARG A NH2 1 
ATOM   1748  N N   . LEU A 1 233 ? -60.206 -4.469  59.712 1.00 46.88  ? 435 LEU A N   1 
ATOM   1749  C CA  . LEU A 1 233 ? -59.931 -4.200  61.122 1.00 46.74  ? 435 LEU A CA  1 
ATOM   1750  C C   . LEU A 1 233 ? -61.000 -3.345  61.795 1.00 47.54  ? 435 LEU A C   1 
ATOM   1751  O O   . LEU A 1 233 ? -60.997 -3.222  63.024 1.00 48.41  ? 435 LEU A O   1 
ATOM   1752  C CB  . LEU A 1 233 ? -58.577 -3.508  61.272 1.00 45.31  ? 435 LEU A CB  1 
ATOM   1753  C CG  . LEU A 1 233 ? -57.343 -4.310  60.874 1.00 45.84  ? 435 LEU A CG  1 
ATOM   1754  C CD1 . LEU A 1 233 ? -56.102 -3.446  60.991 1.00 43.68  ? 435 LEU A CD1 1 
ATOM   1755  C CD2 . LEU A 1 233 ? -57.222 -5.551  61.734 1.00 45.31  ? 435 LEU A CD2 1 
ATOM   1756  N N   . MET A 1 234 ? -61.904 -2.749  61.025 1.00 51.13  ? 436 MET A N   1 
ATOM   1757  C CA  . MET A 1 234 ? -62.971 -1.930  61.581 1.00 52.19  ? 436 MET A CA  1 
ATOM   1758  C C   . MET A 1 234 ? -63.940 -2.773  62.402 1.00 52.29  ? 436 MET A C   1 
ATOM   1759  O O   . MET A 1 234 ? -63.973 -4.002  62.300 1.00 52.26  ? 436 MET A O   1 
ATOM   1760  C CB  . MET A 1 234 ? -63.749 -1.253  60.462 1.00 52.38  ? 436 MET A CB  1 
ATOM   1761  C CG  . MET A 1 234 ? -64.572 -2.259  59.688 1.00 54.43  ? 436 MET A CG  1 
ATOM   1762  S SD  . MET A 1 234 ? -65.240 -1.651  58.144 1.00 59.06  ? 436 MET A SD  1 
ATOM   1763  C CE  . MET A 1 234 ? -63.841 -1.921  57.067 1.00 58.44  ? 436 MET A CE  1 
ATOM   1764  N N   . ASN A 1 235 ? -64.721 -2.097  63.244 1.00 55.97  ? 437 ASN A N   1 
ATOM   1765  C CA  . ASN A 1 235 ? -65.925 -2.696  63.796 1.00 54.66  ? 437 ASN A CA  1 
ATOM   1766  C C   . ASN A 1 235 ? -67.152 -2.178  63.059 1.00 53.98  ? 437 ASN A C   1 
ATOM   1767  O O   . ASN A 1 235 ? -67.274 -0.968  62.832 1.00 54.33  ? 437 ASN A O   1 
ATOM   1768  C CB  . ASN A 1 235 ? -66.043 -2.446  65.314 1.00 59.46  ? 437 ASN A CB  1 
ATOM   1769  C CG  . ASN A 1 235 ? -65.935 -0.978  65.704 1.00 59.99  ? 437 ASN A CG  1 
ATOM   1770  O OD1 . ASN A 1 235 ? -66.391 -0.083  65.002 1.00 60.29  ? 437 ASN A OD1 1 
ATOM   1771  N ND2 . ASN A 1 235 ? -65.313 -0.734  66.851 1.00 59.69  ? 437 ASN A ND2 1 
ATOM   1772  N N   . PRO A 1 236 ? -68.048 -3.060  62.609 1.00 55.28  ? 438 PRO A N   1 
ATOM   1773  C CA  . PRO A 1 236 ? -69.174 -2.631  61.777 1.00 54.61  ? 438 PRO A CA  1 
ATOM   1774  C C   . PRO A 1 236 ? -70.289 -1.965  62.574 1.00 54.78  ? 438 PRO A C   1 
ATOM   1775  O O   . PRO A 1 236 ? -70.247 -0.748  62.757 1.00 55.39  ? 438 PRO A O   1 
ATOM   1776  C CB  . PRO A 1 236 ? -69.657 -3.939  61.154 1.00 51.75  ? 438 PRO A CB  1 
ATOM   1777  C CG  . PRO A 1 236 ? -69.294 -4.973  62.150 1.00 52.26  ? 438 PRO A CG  1 
ATOM   1778  C CD  . PRO A 1 236 ? -68.009 -4.522  62.781 1.00 52.35  ? 438 PRO A CD  1 
ATOM   1779  N N   . GLN A 1 240 ? -67.666 5.633   60.832 1.00 54.48  ? 442 GLN A N   1 
ATOM   1780  C CA  . GLN A 1 240 ? -66.604 6.628   60.928 1.00 53.24  ? 442 GLN A CA  1 
ATOM   1781  C C   . GLN A 1 240 ? -67.152 8.039   60.810 1.00 53.12  ? 442 GLN A C   1 
ATOM   1782  O O   . GLN A 1 240 ? -68.253 8.248   60.305 1.00 53.09  ? 442 GLN A O   1 
ATOM   1783  C CB  . GLN A 1 240 ? -65.547 6.406   59.846 1.00 55.25  ? 442 GLN A CB  1 
ATOM   1784  C CG  . GLN A 1 240 ? -64.729 5.144   60.004 1.00 53.49  ? 442 GLN A CG  1 
ATOM   1785  C CD  . GLN A 1 240 ? -63.736 4.960   58.875 1.00 53.62  ? 442 GLN A CD  1 
ATOM   1786  O OE1 . GLN A 1 240 ? -63.932 5.467   57.772 1.00 52.53  ? 442 GLN A OE1 1 
ATOM   1787  N NE2 . GLN A 1 240 ? -62.657 4.239   59.148 1.00 53.74  ? 442 GLN A NE2 1 
ATOM   1788  N N   . TYR A 1 241 ? -66.372 9.006   61.281 1.00 53.14  ? 443 TYR A N   1 
ATOM   1789  C CA  . TYR A 1 241 ? -66.697 10.411  61.093 1.00 51.70  ? 443 TYR A CA  1 
ATOM   1790  C C   . TYR A 1 241 ? -66.024 11.007  59.866 1.00 51.33  ? 443 TYR A C   1 
ATOM   1791  O O   . TYR A 1 241 ? -66.163 12.210  59.622 1.00 52.61  ? 443 TYR A O   1 
ATOM   1792  C CB  . TYR A 1 241 ? -66.335 11.206  62.350 1.00 51.07  ? 443 TYR A CB  1 
ATOM   1793  C CG  . TYR A 1 241 ? -64.888 11.115  62.774 1.00 50.63  ? 443 TYR A CG  1 
ATOM   1794  C CD1 . TYR A 1 241 ? -63.944 12.010  62.295 1.00 50.23  ? 443 TYR A CD1 1 
ATOM   1795  C CD2 . TYR A 1 241 ? -64.471 10.146  63.675 1.00 51.50  ? 443 TYR A CD2 1 
ATOM   1796  C CE1 . TYR A 1 241 ? -62.623 11.932  62.692 1.00 50.39  ? 443 TYR A CE1 1 
ATOM   1797  C CE2 . TYR A 1 241 ? -63.155 10.061  64.075 1.00 51.56  ? 443 TYR A CE2 1 
ATOM   1798  C CZ  . TYR A 1 241 ? -62.236 10.956  63.581 1.00 51.18  ? 443 TYR A CZ  1 
ATOM   1799  O OH  . TYR A 1 241 ? -60.923 10.875  63.977 1.00 51.01  ? 443 TYR A OH  1 
ATOM   1800  N N   . LEU A 1 242 ? -65.291 10.200  59.107 1.00 51.09  ? 444 LEU A N   1 
ATOM   1801  C CA  . LEU A 1 242 ? -64.755 10.610  57.820 1.00 51.24  ? 444 LEU A CA  1 
ATOM   1802  C C   . LEU A 1 242 ? -65.817 10.507  56.732 1.00 51.85  ? 444 LEU A C   1 
ATOM   1803  O O   . LEU A 1 242 ? -66.800 9.773   56.860 1.00 52.14  ? 444 LEU A O   1 
ATOM   1804  C CB  . LEU A 1 242 ? -63.546 9.755   57.450 1.00 52.25  ? 444 LEU A CB  1 
ATOM   1805  C CG  . LEU A 1 242 ? -62.345 9.909   58.378 1.00 51.67  ? 444 LEU A CG  1 
ATOM   1806  C CD1 . LEU A 1 242 ? -61.265 8.925   57.996 1.00 50.94  ? 444 LEU A CD1 1 
ATOM   1807  C CD2 . LEU A 1 242 ? -61.821 11.334  58.336 1.00 50.88  ? 444 LEU A CD2 1 
ATOM   1808  N N   . TYR A 1 243 ? -65.612 11.260  55.658 1.00 50.12  ? 445 TYR A N   1 
ATOM   1809  C CA  . TYR A 1 243 ? -66.479 11.243  54.492 1.00 50.14  ? 445 TYR A CA  1 
ATOM   1810  C C   . TYR A 1 243 ? -65.678 10.862  53.255 1.00 50.17  ? 445 TYR A C   1 
ATOM   1811  O O   . TYR A 1 243 ? -64.446 10.906  53.247 1.00 50.13  ? 445 TYR A O   1 
ATOM   1812  C CB  . TYR A 1 243 ? -67.149 12.604  54.266 1.00 47.08  ? 445 TYR A CB  1 
ATOM   1813  C CG  . TYR A 1 243 ? -68.199 12.983  55.283 1.00 49.27  ? 445 TYR A CG  1 
ATOM   1814  C CD1 . TYR A 1 243 ? -69.533 12.677  55.073 1.00 50.46  ? 445 TYR A CD1 1 
ATOM   1815  C CD2 . TYR A 1 243 ? -67.858 13.646  56.452 1.00 49.55  ? 445 TYR A CD2 1 
ATOM   1816  C CE1 . TYR A 1 243 ? -70.496 13.025  55.989 1.00 51.22  ? 445 TYR A CE1 1 
ATOM   1817  C CE2 . TYR A 1 243 ? -68.818 13.993  57.380 1.00 50.26  ? 445 TYR A CE2 1 
ATOM   1818  C CZ  . TYR A 1 243 ? -70.136 13.678  57.143 1.00 50.96  ? 445 TYR A CZ  1 
ATOM   1819  O OH  . TYR A 1 243 ? -71.101 14.020  58.061 1.00 52.10  ? 445 TYR A OH  1 
ATOM   1820  N N   . TYR A 1 244 ? -66.399 10.476  52.206 1.00 53.38  ? 446 TYR A N   1 
ATOM   1821  C CA  . TYR A 1 244 ? -65.802 10.114  50.930 1.00 53.73  ? 446 TYR A CA  1 
ATOM   1822  C C   . TYR A 1 244 ? -66.653 10.712  49.821 1.00 54.09  ? 446 TYR A C   1 
ATOM   1823  O O   . TYR A 1 244 ? -67.764 11.191  50.056 1.00 53.92  ? 446 TYR A O   1 
ATOM   1824  C CB  . TYR A 1 244 ? -65.684 8.591   50.773 1.00 51.44  ? 446 TYR A CB  1 
ATOM   1825  C CG  . TYR A 1 244 ? -67.013 7.870   50.710 1.00 51.82  ? 446 TYR A CG  1 
ATOM   1826  C CD1 . TYR A 1 244 ? -67.617 7.589   49.491 1.00 50.82  ? 446 TYR A CD1 1 
ATOM   1827  C CD2 . TYR A 1 244 ? -67.672 7.487   51.868 1.00 52.80  ? 446 TYR A CD2 1 
ATOM   1828  C CE1 . TYR A 1 244 ? -68.828 6.936   49.428 1.00 52.61  ? 446 TYR A CE1 1 
ATOM   1829  C CE2 . TYR A 1 244 ? -68.885 6.836   51.815 1.00 53.64  ? 446 TYR A CE2 1 
ATOM   1830  C CZ  . TYR A 1 244 ? -69.458 6.563   50.593 1.00 53.95  ? 446 TYR A CZ  1 
ATOM   1831  O OH  . TYR A 1 244 ? -70.668 5.912   50.535 1.00 54.55  ? 446 TYR A OH  1 
ATOM   1832  N N   . LEU A 1 245 ? -66.132 10.676  48.599 1.00 54.62  ? 447 LEU A N   1 
ATOM   1833  C CA  . LEU A 1 245 ? -66.824 11.254  47.453 1.00 56.29  ? 447 LEU A CA  1 
ATOM   1834  C C   . LEU A 1 245 ? -67.675 10.166  46.809 1.00 58.17  ? 447 LEU A C   1 
ATOM   1835  O O   . LEU A 1 245 ? -67.145 9.250   46.170 1.00 58.88  ? 447 LEU A O   1 
ATOM   1836  C CB  . LEU A 1 245 ? -65.812 11.827  46.465 1.00 55.34  ? 447 LEU A CB  1 
ATOM   1837  C CG  . LEU A 1 245 ? -66.309 12.438  45.157 1.00 55.64  ? 447 LEU A CG  1 
ATOM   1838  C CD1 . LEU A 1 245 ? -67.161 13.659  45.428 1.00 54.59  ? 447 LEU A CD1 1 
ATOM   1839  C CD2 . LEU A 1 245 ? -65.131 12.791  44.266 1.00 56.27  ? 447 LEU A CD2 1 
ATOM   1840  N N   . SER A 1 246 ? -68.994 10.265  46.974 1.00 56.10  ? 448 SER A N   1 
ATOM   1841  C CA  . SER A 1 246 ? -69.901 9.247   46.457 1.00 57.75  ? 448 SER A CA  1 
ATOM   1842  C C   . SER A 1 246 ? -70.264 9.451   44.991 1.00 59.38  ? 448 SER A C   1 
ATOM   1843  O O   . SER A 1 246 ? -70.249 8.491   44.214 1.00 60.67  ? 448 SER A O   1 
ATOM   1844  C CB  . SER A 1 246 ? -71.176 9.202   47.301 1.00 56.79  ? 448 SER A CB  1 
ATOM   1845  O OG  . SER A 1 246 ? -71.889 10.420  47.210 1.00 58.38  ? 448 SER A OG  1 
ATOM   1846  N N   . LYS A 1 247 ? -70.583 10.680  44.593 1.00 57.82  ? 449 LYS A N   1 
ATOM   1847  C CA  . LYS A 1 247 ? -71.106 10.951  43.260 1.00 59.45  ? 449 LYS A CA  1 
ATOM   1848  C C   . LYS A 1 247 ? -70.368 12.128  42.647 1.00 60.50  ? 449 LYS A C   1 
ATOM   1849  O O   . LYS A 1 247 ? -70.249 13.181  43.278 1.00 61.40  ? 449 LYS A O   1 
ATOM   1850  C CB  . LYS A 1 247 ? -72.608 11.260  43.298 1.00 59.05  ? 449 LYS A CB  1 
ATOM   1851  C CG  . LYS A 1 247 ? -73.495 10.099  43.697 1.00 61.42  ? 449 LYS A CG  1 
ATOM   1852  C CD  . LYS A 1 247 ? -74.946 10.540  43.769 1.00 64.22  ? 449 LYS A CD  1 
ATOM   1853  C CE  . LYS A 1 247 ? -75.859 9.390   44.149 1.00 67.00  ? 449 LYS A CE  1 
ATOM   1854  N NZ  . LYS A 1 247 ? -77.275 9.831   44.281 1.00 69.76  ? 449 LYS A NZ  1 
ATOM   1855  N N   . THR A 1 248 ? -69.866 11.946  41.428 1.00 61.04  ? 450 THR A N   1 
ATOM   1856  C CA  . THR A 1 248 ? -69.291 13.047  40.672 1.00 62.13  ? 450 THR A CA  1 
ATOM   1857  C C   . THR A 1 248 ? -70.261 13.655  39.667 1.00 63.38  ? 450 THR A C   1 
ATOM   1858  O O   . THR A 1 248 ? -69.934 14.681  39.061 1.00 63.36  ? 450 THR A O   1 
ATOM   1859  C CB  . THR A 1 248 ? -68.028 12.586  39.939 1.00 58.65  ? 450 THR A CB  1 
ATOM   1860  O OG1 . THR A 1 248 ? -68.366 11.546  39.016 1.00 59.31  ? 450 THR A OG1 1 
ATOM   1861  C CG2 . THR A 1 248 ? -67.017 12.054  40.931 1.00 57.83  ? 450 THR A CG2 1 
ATOM   1862  N N   . ILE A 1 249 ? -71.444 13.065  39.490 1.00 63.94  ? 451 ILE A N   1 
ATOM   1863  C CA  . ILE A 1 249 ? -72.455 13.574  38.572 1.00 65.73  ? 451 ILE A CA  1 
ATOM   1864  C C   . ILE A 1 249 ? -73.835 13.304  39.152 1.00 67.39  ? 451 ILE A C   1 
ATOM   1865  O O   . ILE A 1 249 ? -74.030 12.379  39.945 1.00 67.92  ? 451 ILE A O   1 
ATOM   1866  C CB  . ILE A 1 249 ? -72.344 12.961  37.156 1.00 67.46  ? 451 ILE A CB  1 
ATOM   1867  C CG1 . ILE A 1 249 ? -72.377 11.434  37.222 1.00 67.46  ? 451 ILE A CG1 1 
ATOM   1868  C CG2 . ILE A 1 249 ? -71.122 13.479  36.422 1.00 67.46  ? 451 ILE A CG2 1 
ATOM   1869  C CD1 . ILE A 1 249 ? -72.450 10.774  35.869 1.00 67.46  ? 451 ILE A CD1 1 
ATOM   1870  N N   . ASN A 1 250 ? -74.800 14.130  38.742 1.00 71.58  ? 452 ASN A N   1 
ATOM   1871  C CA  . ASN A 1 250 ? -76.164 13.989  39.238 1.00 73.95  ? 452 ASN A CA  1 
ATOM   1872  C C   . ASN A 1 250 ? -76.899 12.861  38.526 1.00 75.43  ? 452 ASN A C   1 
ATOM   1873  O O   . ASN A 1 250 ? -77.709 12.156  39.138 1.00 75.58  ? 452 ASN A O   1 
ATOM   1874  C CB  . ASN A 1 250 ? -76.915 15.309  39.067 1.00 67.21  ? 452 ASN A CB  1 
ATOM   1875  C CG  . ASN A 1 250 ? -76.316 16.434  39.890 1.00 69.41  ? 452 ASN A CG  1 
ATOM   1876  O OD1 . ASN A 1 250 ? -76.027 17.512  39.371 1.00 70.89  ? 452 ASN A OD1 1 
ATOM   1877  N ND2 . ASN A 1 250 ? -76.147 16.195  41.184 1.00 70.73  ? 452 ASN A ND2 1 
ATOM   1878  N N   . GLY A 1 251 ? -76.635 12.678  37.238 1.00 76.05  ? 453 GLY A N   1 
ATOM   1879  C CA  . GLY A 1 251 ? -77.312 11.648  36.478 1.00 78.40  ? 453 GLY A CA  1 
ATOM   1880  C C   . GLY A 1 251 ? -76.881 11.687  35.027 1.00 80.41  ? 453 GLY A C   1 
ATOM   1881  O O   . GLY A 1 251 ? -75.843 12.256  34.681 1.00 81.40  ? 453 GLY A O   1 
ATOM   1882  N N   . SER A 1 252 ? -77.702 11.068  34.184 1.00 86.28  ? 454 SER A N   1 
ATOM   1883  C CA  . SER A 1 252 ? -77.413 11.033  32.758 1.00 86.78  ? 454 SER A CA  1 
ATOM   1884  C C   . SER A 1 252 ? -77.793 12.354  32.103 1.00 86.03  ? 454 SER A C   1 
ATOM   1885  O O   . SER A 1 252 ? -78.899 12.866  32.292 1.00 85.51  ? 454 SER A O   1 
ATOM   1886  C CB  . SER A 1 252 ? -78.165 9.884   32.088 1.00 83.60  ? 454 SER A CB  1 
ATOM   1887  O OG  . SER A 1 252 ? -79.566 10.078  32.169 1.00 85.60  ? 454 SER A OG  1 
ATOM   1888  N N   . GLY A 1 253 ? -76.869 12.905  31.333 1.00 83.48  ? 455 GLY A N   1 
ATOM   1889  C CA  . GLY A 1 253 ? -77.117 14.131  30.608 1.00 82.89  ? 455 GLY A CA  1 
ATOM   1890  C C   . GLY A 1 253 ? -75.837 14.928  30.456 1.00 82.73  ? 455 GLY A C   1 
ATOM   1891  O O   . GLY A 1 253 ? -74.756 14.460  30.794 1.00 82.50  ? 455 GLY A O   1 
ATOM   1892  N N   . GLN A 1 254 ? -75.995 16.142  29.943 1.00 81.01  ? 456 GLN A N   1 
ATOM   1893  C CA  . GLN A 1 254 ? -74.893 17.067  29.735 1.00 81.44  ? 456 GLN A CA  1 
ATOM   1894  C C   . GLN A 1 254 ? -74.767 18.010  30.924 1.00 79.73  ? 456 GLN A C   1 
ATOM   1895  O O   . GLN A 1 254 ? -75.766 18.420  31.521 1.00 79.88  ? 456 GLN A O   1 
ATOM   1896  C CB  . GLN A 1 254 ? -75.100 17.877  28.454 1.00 77.93  ? 456 GLN A CB  1 
ATOM   1897  C CG  . GLN A 1 254 ? -75.102 17.051  27.179 1.00 83.69  ? 456 GLN A CG  1 
ATOM   1898  C CD  . GLN A 1 254 ? -73.754 16.434  26.883 1.00 87.05  ? 456 GLN A CD  1 
ATOM   1899  O OE1 . GLN A 1 254 ? -73.523 15.256  27.151 1.00 87.96  ? 456 GLN A OE1 1 
ATOM   1900  N NE2 . GLN A 1 254 ? -72.853 17.230  26.320 1.00 88.20  ? 456 GLN A NE2 1 
ATOM   1901  N N   . ASN A 1 255 ? -73.520 18.340  31.268 1.00 78.28  ? 457 ASN A N   1 
ATOM   1902  C CA  . ASN A 1 255 ? -73.221 19.321  32.313 1.00 76.54  ? 457 ASN A CA  1 
ATOM   1903  C C   . ASN A 1 255 ? -73.823 18.910  33.655 1.00 74.60  ? 457 ASN A C   1 
ATOM   1904  O O   . ASN A 1 255 ? -74.435 19.718  34.356 1.00 73.69  ? 457 ASN A O   1 
ATOM   1905  C CB  . ASN A 1 255 ? -73.703 20.716  31.907 1.00 77.63  ? 457 ASN A CB  1 
ATOM   1906  C CG  . ASN A 1 255 ? -72.919 21.286  30.746 1.00 78.91  ? 457 ASN A CG  1 
ATOM   1907  O OD1 . ASN A 1 255 ? -71.776 20.902  30.507 1.00 79.71  ? 457 ASN A OD1 1 
ATOM   1908  N ND2 . ASN A 1 255 ? -73.533 22.206  30.013 1.00 79.65  ? 457 ASN A ND2 1 
ATOM   1909  N N   . GLN A 1 256 ? -73.653 17.641  34.014 1.00 73.52  ? 458 GLN A N   1 
ATOM   1910  C CA  . GLN A 1 256 ? -74.213 17.088  35.239 1.00 71.76  ? 458 GLN A CA  1 
ATOM   1911  C C   . GLN A 1 256 ? -73.231 17.084  36.402 1.00 69.93  ? 458 GLN A C   1 
ATOM   1912  O O   . GLN A 1 256 ? -73.556 16.538  37.460 1.00 69.85  ? 458 GLN A O   1 
ATOM   1913  C CB  . GLN A 1 256 ? -74.723 15.668  34.990 1.00 74.64  ? 458 GLN A CB  1 
ATOM   1914  C CG  . GLN A 1 256 ? -75.889 15.600  34.030 1.00 77.24  ? 458 GLN A CG  1 
ATOM   1915  C CD  . GLN A 1 256 ? -77.075 16.407  34.509 1.00 79.63  ? 458 GLN A CD  1 
ATOM   1916  O OE1 . GLN A 1 256 ? -77.383 16.434  35.700 1.00 80.82  ? 458 GLN A OE1 1 
ATOM   1917  N NE2 . GLN A 1 256 ? -77.749 17.074  33.580 1.00 80.96  ? 458 GLN A NE2 1 
ATOM   1918  N N   . GLN A 1 257 ? -72.050 17.655  36.204 1.00 68.94  ? 459 GLN A N   1 
ATOM   1919  C CA  . GLN A 1 257 ? -71.016 17.683  37.234 1.00 67.03  ? 459 GLN A CA  1 
ATOM   1920  C C   . GLN A 1 257 ? -71.489 18.127  38.615 1.00 66.23  ? 459 GLN A C   1 
ATOM   1921  O O   . GLN A 1 257 ? -72.160 19.142  38.756 1.00 66.50  ? 459 GLN A O   1 
ATOM   1922  C CB  . GLN A 1 257 ? -69.850 18.567  36.793 1.00 68.79  ? 459 GLN A CB  1 
ATOM   1923  C CG  . GLN A 1 257 ? -69.125 18.081  35.553 1.00 69.64  ? 459 GLN A CG  1 
ATOM   1924  C CD  . GLN A 1 257 ? -69.887 18.382  34.285 1.00 69.01  ? 459 GLN A CD  1 
ATOM   1925  O OE1 . GLN A 1 257 ? -71.113 18.443  34.288 1.00 69.04  ? 459 GLN A OE1 1 
ATOM   1926  N NE2 . GLN A 1 257 ? -69.164 18.570  33.190 1.00 67.96  ? 459 GLN A NE2 1 
ATOM   1927  N N   . THR A 1 258 ? -71.129 17.349  39.630 1.00 62.38  ? 460 THR A N   1 
ATOM   1928  C CA  . THR A 1 258 ? -71.480 17.657  41.012 1.00 62.28  ? 460 THR A CA  1 
ATOM   1929  C C   . THR A 1 258 ? -70.511 16.992  41.985 1.00 60.42  ? 460 THR A C   1 
ATOM   1930  O O   . THR A 1 258 ? -69.784 16.078  41.616 1.00 60.77  ? 460 THR A O   1 
ATOM   1931  C CB  . THR A 1 258 ? -72.905 17.195  41.357 1.00 63.00  ? 460 THR A CB  1 
ATOM   1932  O OG1 . THR A 1 258 ? -73.317 17.797  42.587 1.00 62.63  ? 460 THR A OG1 1 
ATOM   1933  C CG2 . THR A 1 258 ? -72.953 15.690  41.509 1.00 65.13  ? 460 THR A CG2 1 
ATOM   1934  N N   . LEU A 1 259 ? -70.476 17.480  43.218 1.00 59.42  ? 461 LEU A N   1 
ATOM   1935  C CA  . LEU A 1 259 ? -69.640 16.883  44.246 1.00 56.62  ? 461 LEU A CA  1 
ATOM   1936  C C   . LEU A 1 259 ? -70.534 16.472  45.413 1.00 56.76  ? 461 LEU A C   1 
ATOM   1937  O O   . LEU A 1 259 ? -71.272 17.289  45.953 1.00 58.05  ? 461 LEU A O   1 
ATOM   1938  C CB  . LEU A 1 259 ? -68.562 17.859  44.707 1.00 60.37  ? 461 LEU A CB  1 
ATOM   1939  C CG  . LEU A 1 259 ? -67.367 18.040  43.768 1.00 58.23  ? 461 LEU A CG  1 
ATOM   1940  C CD1 . LEU A 1 259 ? -66.422 19.108  44.293 1.00 56.43  ? 461 LEU A CD1 1 
ATOM   1941  C CD2 . LEU A 1 259 ? -66.630 16.725  43.570 1.00 56.51  ? 461 LEU A CD2 1 
ATOM   1942  N N   . LYS A 1 260 ? -70.458 15.204  45.803 1.00 58.44  ? 462 LYS A N   1 
ATOM   1943  C CA  . LYS A 1 260 ? -71.269 14.674  46.894 1.00 57.87  ? 462 LYS A CA  1 
ATOM   1944  C C   . LYS A 1 260 ? -70.417 13.921  47.900 1.00 56.92  ? 462 LYS A C   1 
ATOM   1945  O O   . LYS A 1 260 ? -69.521 13.176  47.522 1.00 56.44  ? 462 LYS A O   1 
ATOM   1946  C CB  . LYS A 1 260 ? -72.349 13.745  46.345 1.00 56.89  ? 462 LYS A CB  1 
ATOM   1947  C CG  . LYS A 1 260 ? -73.358 14.431  45.448 1.00 58.66  ? 462 LYS A CG  1 
ATOM   1948  C CD  . LYS A 1 260 ? -74.258 15.348  46.248 1.00 59.46  ? 462 LYS A CD  1 
ATOM   1949  C CE  . LYS A 1 260 ? -75.292 16.006  45.355 1.00 61.62  ? 462 LYS A CE  1 
ATOM   1950  N NZ  . LYS A 1 260 ? -76.321 16.718  46.158 1.00 63.29  ? 462 LYS A NZ  1 
ATOM   1951  N N   . PHE A 1 261 ? -70.714 14.098  49.180 1.00 55.37  ? 463 PHE A N   1 
ATOM   1952  C CA  . PHE A 1 261 ? -69.956 13.434  50.226 1.00 54.00  ? 463 PHE A CA  1 
ATOM   1953  C C   . PHE A 1 261 ? -70.843 12.635  51.167 1.00 53.76  ? 463 PHE A C   1 
ATOM   1954  O O   . PHE A 1 261 ? -71.738 13.177  51.804 1.00 54.10  ? 463 PHE A O   1 
ATOM   1955  C CB  . PHE A 1 261 ? -69.111 14.453  50.979 1.00 55.72  ? 463 PHE A CB  1 
ATOM   1956  C CG  . PHE A 1 261 ? -68.158 15.198  50.095 1.00 54.20  ? 463 PHE A CG  1 
ATOM   1957  C CD1 . PHE A 1 261 ? -66.925 14.661  49.781 1.00 53.28  ? 463 PHE A CD1 1 
ATOM   1958  C CD2 . PHE A 1 261 ? -68.509 16.418  49.553 1.00 53.97  ? 463 PHE A CD2 1 
ATOM   1959  C CE1 . PHE A 1 261 ? -66.050 15.332  48.956 1.00 52.18  ? 463 PHE A CE1 1 
ATOM   1960  C CE2 . PHE A 1 261 ? -67.638 17.098  48.729 1.00 53.07  ? 463 PHE A CE2 1 
ATOM   1961  C CZ  . PHE A 1 261 ? -66.407 16.555  48.429 1.00 52.21  ? 463 PHE A CZ  1 
ATOM   1962  N N   . SER A 1 262 ? -70.576 11.336  51.245 1.00 52.94  ? 464 SER A N   1 
ATOM   1963  C CA  . SER A 1 262 ? -71.340 10.419  52.074 1.00 53.44  ? 464 SER A CA  1 
ATOM   1964  C C   . SER A 1 262 ? -70.480 9.971   53.245 1.00 53.58  ? 464 SER A C   1 
ATOM   1965  O O   . SER A 1 262 ? -69.256 10.120  53.235 1.00 53.49  ? 464 SER A O   1 
ATOM   1966  C CB  . SER A 1 262 ? -71.827 9.203   51.276 1.00 53.51  ? 464 SER A CB  1 
ATOM   1967  O OG  . SER A 1 262 ? -72.730 9.589   50.255 1.00 53.76  ? 464 SER A OG  1 
ATOM   1968  N N   . VAL A 1 263 ? -71.136 9.423   54.262 1.00 54.03  ? 465 VAL A N   1 
ATOM   1969  C CA  . VAL A 1 263 ? -70.437 8.936   55.444 1.00 55.27  ? 465 VAL A CA  1 
ATOM   1970  C C   . VAL A 1 263 ? -69.834 7.573   55.142 1.00 55.95  ? 465 VAL A C   1 
ATOM   1971  O O   . VAL A 1 263 ? -70.494 6.699   54.567 1.00 56.24  ? 465 VAL A O   1 
ATOM   1972  C CB  . VAL A 1 263 ? -71.390 8.852   56.651 1.00 52.82  ? 465 VAL A CB  1 
ATOM   1973  C CG1 . VAL A 1 263 ? -70.651 8.326   57.873 1.00 53.07  ? 465 VAL A CG1 1 
ATOM   1974  C CG2 . VAL A 1 263 ? -72.026 10.192  56.938 1.00 53.43  ? 465 VAL A CG2 1 
ATOM   1975  N N   . ALA A 1 264 ? -68.579 7.383   55.532 1.00 54.94  ? 466 ALA A N   1 
ATOM   1976  C CA  . ALA A 1 264 ? -67.969 6.064   55.469 1.00 56.16  ? 466 ALA A CA  1 
ATOM   1977  C C   . ALA A 1 264 ? -68.502 5.214   56.615 1.00 57.63  ? 466 ALA A C   1 
ATOM   1978  O O   . ALA A 1 264 ? -68.353 5.574   57.786 1.00 58.09  ? 466 ALA A O   1 
ATOM   1979  C CB  . ALA A 1 264 ? -66.448 6.173   55.542 1.00 57.51  ? 466 ALA A CB  1 
ATOM   1980  N N   . GLY A 1 265 ? -69.116 4.084   56.277 1.00 62.02  ? 467 GLY A N   1 
ATOM   1981  C CA  . GLY A 1 265 ? -69.786 3.267   57.259 1.00 62.86  ? 467 GLY A CA  1 
ATOM   1982  C C   . GLY A 1 265 ? -69.827 1.802   56.879 1.00 63.12  ? 467 GLY A C   1 
ATOM   1983  O O   . GLY A 1 265 ? -69.258 1.379   55.869 1.00 62.87  ? 467 GLY A O   1 
ATOM   1984  N N   . PRO A 1 266 ? -70.497 0.993   57.701 1.00 61.09  ? 468 PRO A N   1 
ATOM   1985  C CA  . PRO A 1 266 ? -70.535 -0.455  57.440 1.00 61.48  ? 468 PRO A CA  1 
ATOM   1986  C C   . PRO A 1 266 ? -71.196 -0.833  56.128 1.00 62.08  ? 468 PRO A C   1 
ATOM   1987  O O   . PRO A 1 266 ? -70.942 -1.932  55.618 1.00 61.95  ? 468 PRO A O   1 
ATOM   1988  C CB  . PRO A 1 266 ? -71.325 -0.995  58.640 1.00 60.39  ? 468 PRO A CB  1 
ATOM   1989  C CG  . PRO A 1 266 ? -71.109 0.013   59.709 1.00 60.31  ? 468 PRO A CG  1 
ATOM   1990  C CD  . PRO A 1 266 ? -71.093 1.332   59.003 1.00 60.68  ? 468 PRO A CD  1 
ATOM   1991  N N   . SER A 1 267 ? -72.043 0.033   55.567 1.00 62.84  ? 469 SER A N   1 
ATOM   1992  C CA  . SER A 1 267 ? -72.701 -0.298  54.308 1.00 63.62  ? 469 SER A CA  1 
ATOM   1993  C C   . SER A 1 267 ? -71.692 -0.507  53.188 1.00 63.58  ? 469 SER A C   1 
ATOM   1994  O O   . SER A 1 267 ? -71.704 -1.555  52.535 1.00 63.78  ? 469 SER A O   1 
ATOM   1995  C CB  . SER A 1 267 ? -73.699 0.795   53.929 1.00 65.53  ? 469 SER A CB  1 
ATOM   1996  O OG  . SER A 1 267 ? -73.042 2.027   53.689 1.00 70.07  ? 469 SER A OG  1 
ATOM   1997  N N   . ASN A 1 268 ? -70.818 0.466   52.953 1.00 65.24  ? 470 ASN A N   1 
ATOM   1998  C CA  . ASN A 1 268 ? -69.704 0.319   52.020 1.00 63.96  ? 470 ASN A CA  1 
ATOM   1999  C C   . ASN A 1 268 ? -68.416 0.377   52.834 1.00 62.50  ? 470 ASN A C   1 
ATOM   2000  O O   . ASN A 1 268 ? -68.031 1.441   53.327 1.00 61.37  ? 470 ASN A O   1 
ATOM   2001  C CB  . ASN A 1 268 ? -69.742 1.397   50.941 1.00 60.52  ? 470 ASN A CB  1 
ATOM   2002  C CG  . ASN A 1 268 ? -68.741 1.145   49.831 1.00 63.16  ? 470 ASN A CG  1 
ATOM   2003  O OD1 . ASN A 1 268 ? -68.366 0.004   49.564 1.00 64.00  ? 470 ASN A OD1 1 
ATOM   2004  N ND2 . ASN A 1 268 ? -68.321 2.210   49.162 1.00 63.99  ? 470 ASN A ND2 1 
ATOM   2005  N N   . MET A 1 269 ? -67.748 -0.766  52.969 1.00 61.42  ? 471 MET A N   1 
ATOM   2006  C CA  . MET A 1 269 ? -66.525 -0.856  53.752 1.00 61.20  ? 471 MET A CA  1 
ATOM   2007  C C   . MET A 1 269 ? -65.264 -0.725  52.913 1.00 60.00  ? 471 MET A C   1 
ATOM   2008  O O   . MET A 1 269 ? -64.165 -0.746  53.474 1.00 60.67  ? 471 MET A O   1 
ATOM   2009  C CB  . MET A 1 269 ? -66.477 -2.183  54.512 1.00 60.68  ? 471 MET A CB  1 
ATOM   2010  C CG  . MET A 1 269 ? -67.522 -2.329  55.597 1.00 63.43  ? 471 MET A CG  1 
ATOM   2011  S SD  . MET A 1 269 ? -67.404 -3.932  56.412 1.00 65.33  ? 471 MET A SD  1 
ATOM   2012  C CE  . MET A 1 269 ? -68.731 -3.806  57.603 1.00 65.48  ? 471 MET A CE  1 
ATOM   2013  N N   . ALA A 1 270 ? -65.391 -0.594  51.593 1.00 60.24  ? 472 ALA A N   1 
ATOM   2014  C CA  . ALA A 1 270 ? -64.206 -0.521  50.747 1.00 58.53  ? 472 ALA A CA  1 
ATOM   2015  C C   . ALA A 1 270 ? -63.573 0.864   50.769 1.00 57.59  ? 472 ALA A C   1 
ATOM   2016  O O   . ALA A 1 270 ? -62.347 0.983   50.670 1.00 57.43  ? 472 ALA A O   1 
ATOM   2017  C CB  . ALA A 1 270 ? -64.561 -0.917  49.315 1.00 55.68  ? 472 ALA A CB  1 
ATOM   2018  N N   . VAL A 1 271 ? -64.381 1.917   50.903 1.00 55.90  ? 473 VAL A N   1 
ATOM   2019  C CA  . VAL A 1 271 ? -63.902 3.283   50.735 1.00 54.75  ? 473 VAL A CA  1 
ATOM   2020  C C   . VAL A 1 271 ? -63.538 3.954   52.049 1.00 53.24  ? 473 VAL A C   1 
ATOM   2021  O O   . VAL A 1 271 ? -63.149 5.129   52.040 1.00 52.74  ? 473 VAL A O   1 
ATOM   2022  C CB  . VAL A 1 271 ? -64.940 4.138   49.985 1.00 52.44  ? 473 VAL A CB  1 
ATOM   2023  C CG1 . VAL A 1 271 ? -65.158 3.593   48.591 1.00 56.79  ? 473 VAL A CG1 1 
ATOM   2024  C CG2 . VAL A 1 271 ? -66.243 4.180   50.761 1.00 53.04  ? 473 VAL A CG2 1 
ATOM   2025  N N   . GLN A 1 272 ? -63.648 3.256   53.175 1.00 54.15  ? 474 GLN A N   1 
ATOM   2026  C CA  . GLN A 1 272 ? -63.360 3.884   54.457 1.00 52.72  ? 474 GLN A CA  1 
ATOM   2027  C C   . GLN A 1 272 ? -61.881 4.223   54.583 1.00 52.26  ? 474 GLN A C   1 
ATOM   2028  O O   . GLN A 1 272 ? -61.027 3.660   53.894 1.00 52.76  ? 474 GLN A O   1 
ATOM   2029  C CB  . GLN A 1 272 ? -63.764 2.980   55.616 1.00 53.99  ? 474 GLN A CB  1 
ATOM   2030  C CG  . GLN A 1 272 ? -65.244 2.713   55.742 1.00 57.03  ? 474 GLN A CG  1 
ATOM   2031  C CD  . GLN A 1 272 ? -65.546 1.875   56.960 1.00 58.66  ? 474 GLN A CD  1 
ATOM   2032  O OE1 . GLN A 1 272 ? -64.663 1.209   57.491 1.00 59.90  ? 474 GLN A OE1 1 
ATOM   2033  N NE2 . GLN A 1 272 ? -66.791 1.898   57.408 1.00 60.34  ? 474 GLN A NE2 1 
ATOM   2034  N N   . GLY A 1 273 ? -61.584 5.155   55.483 1.00 50.80  ? 475 GLY A N   1 
ATOM   2035  C CA  . GLY A 1 273 ? -60.202 5.506   55.746 1.00 49.66  ? 475 GLY A CA  1 
ATOM   2036  C C   . GLY A 1 273 ? -59.507 4.430   56.561 1.00 50.42  ? 475 GLY A C   1 
ATOM   2037  O O   . GLY A 1 273 ? -60.111 3.776   57.413 1.00 50.87  ? 475 GLY A O   1 
ATOM   2038  N N   . ARG A 1 274 ? -58.218 4.246   56.289 1.00 43.72  ? 476 ARG A N   1 
ATOM   2039  C CA  . ARG A 1 274 ? -57.422 3.216   56.936 1.00 43.47  ? 476 ARG A CA  1 
ATOM   2040  C C   . ARG A 1 274 ? -56.046 3.764   57.280 1.00 43.21  ? 476 ARG A C   1 
ATOM   2041  O O   . ARG A 1 274 ? -55.477 4.573   56.544 1.00 44.30  ? 476 ARG A O   1 
ATOM   2042  C CB  . ARG A 1 274 ? -57.294 1.978   56.046 1.00 41.80  ? 476 ARG A CB  1 
ATOM   2043  C CG  . ARG A 1 274 ? -58.603 1.243   55.867 1.00 43.35  ? 476 ARG A CG  1 
ATOM   2044  C CD  . ARG A 1 274 ? -58.501 0.092   54.893 1.00 44.70  ? 476 ARG A CD  1 
ATOM   2045  N NE  . ARG A 1 274 ? -59.771 -0.619  54.794 1.00 48.93  ? 476 ARG A NE  1 
ATOM   2046  C CZ  . ARG A 1 274 ? -60.793 -0.222  54.045 1.00 49.80  ? 476 ARG A CZ  1 
ATOM   2047  N NH1 . ARG A 1 274 ? -60.701 0.886   53.325 1.00 52.61  ? 476 ARG A NH1 1 
ATOM   2048  N NH2 . ARG A 1 274 ? -61.909 -0.934  54.019 1.00 51.90  ? 476 ARG A NH2 1 
ATOM   2049  N N   . ASN A 1 275 ? -55.526 3.322   58.422 1.00 39.35  ? 477 ASN A N   1 
ATOM   2050  C CA  . ASN A 1 275 ? -54.211 3.728   58.894 1.00 38.72  ? 477 ASN A CA  1 
ATOM   2051  C C   . ASN A 1 275 ? -53.065 2.946   58.268 1.00 38.36  ? 477 ASN A C   1 
ATOM   2052  O O   . ASN A 1 275 ? -51.927 3.424   58.300 1.00 37.38  ? 477 ASN A O   1 
ATOM   2053  C CB  . ASN A 1 275 ? -54.136 3.593   60.417 1.00 39.88  ? 477 ASN A CB  1 
ATOM   2054  C CG  . ASN A 1 275 ? -54.828 4.724   61.133 1.00 41.40  ? 477 ASN A CG  1 
ATOM   2055  O OD1 . ASN A 1 275 ? -54.895 5.840   60.626 1.00 43.72  ? 477 ASN A OD1 1 
ATOM   2056  N ND2 . ASN A 1 275 ? -55.366 4.440   62.309 1.00 41.74  ? 477 ASN A ND2 1 
ATOM   2057  N N   . TYR A 1 276 ? -53.319 1.766   57.710 1.00 35.29  ? 478 TYR A N   1 
ATOM   2058  C CA  . TYR A 1 276 ? -52.222 0.939   57.233 1.00 36.35  ? 478 TYR A CA  1 
ATOM   2059  C C   . TYR A 1 276 ? -52.623 0.242   55.944 1.00 37.43  ? 478 TYR A C   1 
ATOM   2060  O O   . TYR A 1 276 ? -53.806 0.017   55.679 1.00 39.56  ? 478 TYR A O   1 
ATOM   2061  C CB  . TYR A 1 276 ? -51.798 -0.077  58.294 1.00 35.50  ? 478 TYR A CB  1 
ATOM   2062  C CG  . TYR A 1 276 ? -51.269 0.581   59.543 1.00 37.71  ? 478 TYR A CG  1 
ATOM   2063  C CD1 . TYR A 1 276 ? -49.943 0.964   59.634 1.00 38.21  ? 478 TYR A CD1 1 
ATOM   2064  C CD2 . TYR A 1 276 ? -52.097 0.830   60.627 1.00 36.90  ? 478 TYR A CD2 1 
ATOM   2065  C CE1 . TYR A 1 276 ? -49.456 1.570   60.765 1.00 38.45  ? 478 TYR A CE1 1 
ATOM   2066  C CE2 . TYR A 1 276 ? -51.617 1.442   61.766 1.00 38.75  ? 478 TYR A CE2 1 
ATOM   2067  C CZ  . TYR A 1 276 ? -50.293 1.808   61.828 1.00 39.57  ? 478 TYR A CZ  1 
ATOM   2068  O OH  . TYR A 1 276 ? -49.801 2.416   62.958 1.00 41.12  ? 478 TYR A OH  1 
ATOM   2069  N N   . ILE A 1 277 ? -51.614 -0.090  55.145 1.00 33.95  ? 479 ILE A N   1 
ATOM   2070  C CA  . ILE A 1 277 ? -51.808 -0.646  53.809 1.00 33.34  ? 479 ILE A CA  1 
ATOM   2071  C C   . ILE A 1 277 ? -50.934 -1.885  53.673 1.00 34.50  ? 479 ILE A C   1 
ATOM   2072  O O   . ILE A 1 277 ? -49.935 -2.038  54.390 1.00 34.87  ? 479 ILE A O   1 
ATOM   2073  C CB  . ILE A 1 277 ? -51.486 0.395   52.711 1.00 35.04  ? 479 ILE A CB  1 
ATOM   2074  C CG1 . ILE A 1 277 ? -50.048 0.889   52.851 1.00 33.41  ? 479 ILE A CG1 1 
ATOM   2075  C CG2 . ILE A 1 277 ? -52.450 1.557   52.783 1.00 33.86  ? 479 ILE A CG2 1 
ATOM   2076  C CD1 . ILE A 1 277 ? -49.611 1.795   51.733 1.00 31.92  ? 479 ILE A CD1 1 
ATOM   2077  N N   . PRO A 1 278 ? -51.290 -2.798  52.771 1.00 34.01  ? 480 PRO A N   1 
ATOM   2078  C CA  . PRO A 1 278 ? -50.530 -4.043  52.641 1.00 34.45  ? 480 PRO A CA  1 
ATOM   2079  C C   . PRO A 1 278 ? -49.138 -3.809  52.081 1.00 35.13  ? 480 PRO A C   1 
ATOM   2080  O O   . PRO A 1 278 ? -48.823 -2.754  51.527 1.00 34.61  ? 480 PRO A O   1 
ATOM   2081  C CB  . PRO A 1 278 ? -51.379 -4.874  51.676 1.00 36.34  ? 480 PRO A CB  1 
ATOM   2082  C CG  . PRO A 1 278 ? -52.084 -3.872  50.870 1.00 36.79  ? 480 PRO A CG  1 
ATOM   2083  C CD  . PRO A 1 278 ? -52.419 -2.768  51.828 1.00 35.57  ? 480 PRO A CD  1 
ATOM   2084  N N   . GLY A 1 279 ? -48.302 -4.833  52.231 1.00 33.39  ? 481 GLY A N   1 
ATOM   2085  C CA  . GLY A 1 279 ? -46.906 -4.757  51.877 1.00 34.46  ? 481 GLY A CA  1 
ATOM   2086  C C   . GLY A 1 279 ? -46.643 -4.712  50.387 1.00 35.33  ? 481 GLY A C   1 
ATOM   2087  O O   . GLY A 1 279 ? -47.562 -4.720  49.563 1.00 35.88  ? 481 GLY A O   1 
ATOM   2088  N N   . PRO A 1 280 ? -45.367 -4.672  50.018 1.00 34.18  ? 482 PRO A N   1 
ATOM   2089  C CA  . PRO A 1 280 ? -44.995 -4.517  48.609 1.00 34.73  ? 482 PRO A CA  1 
ATOM   2090  C C   . PRO A 1 280 ? -45.234 -5.785  47.805 1.00 35.73  ? 482 PRO A C   1 
ATOM   2091  O O   . PRO A 1 280 ? -45.403 -6.878  48.344 1.00 35.83  ? 482 PRO A O   1 
ATOM   2092  C CB  . PRO A 1 280 ? -43.501 -4.189  48.682 1.00 33.03  ? 482 PRO A CB  1 
ATOM   2093  C CG  . PRO A 1 280 ? -43.052 -4.838  49.931 1.00 32.90  ? 482 PRO A CG  1 
ATOM   2094  C CD  . PRO A 1 280 ? -44.188 -4.707  50.897 1.00 32.59  ? 482 PRO A CD  1 
ATOM   2095  N N   . SER A 1 281 ? -45.238 -5.615  46.483 1.00 34.05  ? 483 SER A N   1 
ATOM   2096  C CA  . SER A 1 281 ? -45.514 -6.710  45.565 1.00 34.91  ? 483 SER A CA  1 
ATOM   2097  C C   . SER A 1 281 ? -44.618 -6.612  44.339 1.00 34.33  ? 483 SER A C   1 
ATOM   2098  O O   . SER A 1 281 ? -44.266 -5.518  43.894 1.00 34.77  ? 483 SER A O   1 
ATOM   2099  C CB  . SER A 1 281 ? -46.979 -6.717  45.122 1.00 32.14  ? 483 SER A CB  1 
ATOM   2100  O OG  . SER A 1 281 ? -47.275 -5.568  44.354 1.00 34.58  ? 483 SER A OG  1 
ATOM   2101  N N   . TYR A 1 282 ? -44.226 -7.776  43.819 1.00 36.38  ? 484 TYR A N   1 
ATOM   2102  C CA  . TYR A 1 282 ? -43.517 -7.890  42.545 1.00 34.41  ? 484 TYR A CA  1 
ATOM   2103  C C   . TYR A 1 282 ? -44.166 -9.058  41.809 1.00 33.83  ? 484 TYR A C   1 
ATOM   2104  O O   . TYR A 1 282 ? -43.985 -10.206 42.221 1.00 34.10  ? 484 TYR A O   1 
ATOM   2105  C CB  . TYR A 1 282 ? -42.033 -8.145  42.808 1.00 30.43  ? 484 TYR A CB  1 
ATOM   2106  C CG  . TYR A 1 282 ? -41.096 -8.098  41.627 1.00 29.37  ? 484 TYR A CG  1 
ATOM   2107  C CD1 . TYR A 1 282 ? -40.546 -6.897  41.207 1.00 29.23  ? 484 TYR A CD1 1 
ATOM   2108  C CD2 . TYR A 1 282 ? -40.746 -9.251  40.947 1.00 28.69  ? 484 TYR A CD2 1 
ATOM   2109  C CE1 . TYR A 1 282 ? -39.673 -6.848  40.147 1.00 28.33  ? 484 TYR A CE1 1 
ATOM   2110  C CE2 . TYR A 1 282 ? -39.882 -9.210  39.880 1.00 27.78  ? 484 TYR A CE2 1 
ATOM   2111  C CZ  . TYR A 1 282 ? -39.349 -8.006  39.483 1.00 28.28  ? 484 TYR A CZ  1 
ATOM   2112  O OH  . TYR A 1 282 ? -38.485 -7.966  38.417 1.00 27.97  ? 484 TYR A OH  1 
ATOM   2113  N N   . ARG A 1 283 ? -44.877 -8.802  40.710 1.00 36.46  ? 485 ARG A N   1 
ATOM   2114  C CA  . ARG A 1 283 ? -45.843 -9.798  40.249 1.00 35.95  ? 485 ARG A CA  1 
ATOM   2115  C C   . ARG A 1 283 ? -45.171 -11.021 39.629 1.00 36.03  ? 485 ARG A C   1 
ATOM   2116  O O   . ARG A 1 283 ? -44.229 -10.908 38.842 1.00 35.62  ? 485 ARG A O   1 
ATOM   2117  C CB  . ARG A 1 283 ? -46.837 -9.216  39.238 1.00 38.64  ? 485 ARG A CB  1 
ATOM   2118  C CG  . ARG A 1 283 ? -47.821 -10.309 38.800 1.00 40.24  ? 485 ARG A CG  1 
ATOM   2119  C CD  . ARG A 1 283 ? -48.821 -9.986  37.705 1.00 39.68  ? 485 ARG A CD  1 
ATOM   2120  N NE  . ARG A 1 283 ? -49.913 -9.111  38.107 1.00 40.35  ? 485 ARG A NE  1 
ATOM   2121  C CZ  . ARG A 1 283 ? -50.916 -8.781  37.301 1.00 39.78  ? 485 ARG A CZ  1 
ATOM   2122  N NH1 . ARG A 1 283 ? -50.958 -9.264  36.071 1.00 38.79  ? 485 ARG A NH1 1 
ATOM   2123  N NH2 . ARG A 1 283 ? -51.881 -7.981  37.723 1.00 41.99  ? 485 ARG A NH2 1 
ATOM   2124  N N   . GLN A 1 284 ? -45.683 -12.196 39.986 1.00 36.48  ? 486 GLN A N   1 
ATOM   2125  C CA  . GLN A 1 284 ? -45.337 -13.470 39.376 1.00 37.03  ? 486 GLN A CA  1 
ATOM   2126  C C   . GLN A 1 284 ? -46.427 -13.879 38.393 1.00 37.83  ? 486 GLN A C   1 
ATOM   2127  O O   . GLN A 1 284 ? -47.610 -13.604 38.604 1.00 37.45  ? 486 GLN A O   1 
ATOM   2128  C CB  . GLN A 1 284 ? -45.183 -14.562 40.438 1.00 36.04  ? 486 GLN A CB  1 
ATOM   2129  C CG  . GLN A 1 284 ? -44.060 -14.355 41.431 1.00 37.92  ? 486 GLN A CG  1 
ATOM   2130  C CD  . GLN A 1 284 ? -42.705 -14.320 40.774 1.00 39.78  ? 486 GLN A CD  1 
ATOM   2131  O OE1 . GLN A 1 284 ? -42.440 -15.069 39.835 1.00 40.98  ? 486 GLN A OE1 1 
ATOM   2132  N NE2 . GLN A 1 284 ? -41.831 -13.453 41.268 1.00 40.66  ? 486 GLN A NE2 1 
ATOM   2133  N N   . GLN A 1 285 ? -46.023 -14.543 37.316 1.00 41.91  ? 487 GLN A N   1 
ATOM   2134  C CA  . GLN A 1 285 ? -46.994 -15.084 36.378 1.00 41.97  ? 487 GLN A CA  1 
ATOM   2135  C C   . GLN A 1 285 ? -47.767 -16.228 37.026 1.00 42.40  ? 487 GLN A C   1 
ATOM   2136  O O   . GLN A 1 285 ? -47.225 -16.998 37.822 1.00 42.49  ? 487 GLN A O   1 
ATOM   2137  C CB  . GLN A 1 285 ? -46.289 -15.566 35.111 1.00 45.45  ? 487 GLN A CB  1 
ATOM   2138  C CG  . GLN A 1 285 ? -47.216 -16.048 34.017 1.00 45.36  ? 487 GLN A CG  1 
ATOM   2139  C CD  . GLN A 1 285 ? -48.091 -14.943 33.473 1.00 45.89  ? 487 GLN A CD  1 
ATOM   2140  O OE1 . GLN A 1 285 ? -49.261 -14.834 33.831 1.00 43.23  ? 487 GLN A OE1 1 
ATOM   2141  N NE2 . GLN A 1 285 ? -47.528 -14.115 32.605 1.00 46.06  ? 487 GLN A NE2 1 
ATOM   2142  N N   . ARG A 1 286 ? -49.051 -16.336 36.690 1.00 48.01  ? 488 ARG A N   1 
ATOM   2143  C CA  . ARG A 1 286 ? -49.919 -17.348 37.279 1.00 47.96  ? 488 ARG A CA  1 
ATOM   2144  C C   . ARG A 1 286 ? -49.901 -18.608 36.425 1.00 47.90  ? 488 ARG A C   1 
ATOM   2145  O O   . ARG A 1 286 ? -50.007 -18.534 35.198 1.00 49.57  ? 488 ARG A O   1 
ATOM   2146  C CB  . ARG A 1 286 ? -51.355 -16.843 37.429 1.00 49.15  ? 488 ARG A CB  1 
ATOM   2147  C CG  . ARG A 1 286 ? -52.239 -17.842 38.161 1.00 50.25  ? 488 ARG A CG  1 
ATOM   2148  C CD  . ARG A 1 286 ? -53.688 -17.412 38.293 1.00 52.57  ? 488 ARG A CD  1 
ATOM   2149  N NE  . ARG A 1 286 ? -54.392 -17.377 37.017 1.00 55.71  ? 488 ARG A NE  1 
ATOM   2150  C CZ  . ARG A 1 286 ? -55.600 -16.849 36.854 1.00 58.38  ? 488 ARG A CZ  1 
ATOM   2151  N NH1 . ARG A 1 286 ? -56.175 -16.853 35.661 1.00 56.24  ? 488 ARG A NH1 1 
ATOM   2152  N NH2 . ARG A 1 286 ? -56.243 -16.338 37.892 1.00 61.56  ? 488 ARG A NH2 1 
ATOM   2153  N N   . VAL A 1 287 ? -49.771 -19.759 37.079 1.00 50.30  ? 489 VAL A N   1 
ATOM   2154  C CA  . VAL A 1 287 ? -49.721 -21.051 36.408 1.00 49.89  ? 489 VAL A CA  1 
ATOM   2155  C C   . VAL A 1 287 ? -50.770 -21.964 37.026 1.00 50.41  ? 489 VAL A C   1 
ATOM   2156  O O   . VAL A 1 287 ? -50.819 -22.133 38.249 1.00 51.45  ? 489 VAL A O   1 
ATOM   2157  C CB  . VAL A 1 287 ? -48.321 -21.692 36.501 1.00 49.21  ? 489 VAL A CB  1 
ATOM   2158  C CG1 . VAL A 1 287 ? -48.326 -23.065 35.861 1.00 48.14  ? 489 VAL A CG1 1 
ATOM   2159  C CG2 . VAL A 1 287 ? -47.283 -20.799 35.848 1.00 50.05  ? 489 VAL A CG2 1 
ATOM   2160  N N   . SER A 1 288 ? -51.611 -22.548 36.181 1.00 51.28  ? 490 SER A N   1 
ATOM   2161  C CA  . SER A 1 288 ? -52.676 -23.437 36.619 1.00 51.73  ? 490 SER A CA  1 
ATOM   2162  C C   . SER A 1 288 ? -52.206 -24.884 36.582 1.00 52.63  ? 490 SER A C   1 
ATOM   2163  O O   . SER A 1 288 ? -51.550 -25.310 35.628 1.00 51.21  ? 490 SER A O   1 
ATOM   2164  C CB  . SER A 1 288 ? -53.912 -23.277 35.738 1.00 53.74  ? 490 SER A CB  1 
ATOM   2165  O OG  . SER A 1 288 ? -54.925 -24.187 36.123 1.00 53.81  ? 490 SER A OG  1 
ATOM   2166  N N   . THR A 1 289 ? -52.553 -25.639 37.626 1.00 51.78  ? 491 THR A N   1 
ATOM   2167  C CA  . THR A 1 289 ? -52.179 -27.045 37.690 1.00 54.31  ? 491 THR A CA  1 
ATOM   2168  C C   . THR A 1 289 ? -52.798 -27.864 36.567 1.00 56.14  ? 491 THR A C   1 
ATOM   2169  O O   . THR A 1 289 ? -52.179 -28.831 36.111 1.00 57.24  ? 491 THR A O   1 
ATOM   2170  C CB  . THR A 1 289 ? -52.583 -27.642 39.036 1.00 54.13  ? 491 THR A CB  1 
ATOM   2171  O OG1 . THR A 1 289 ? -54.002 -27.539 39.199 1.00 57.53  ? 491 THR A OG1 1 
ATOM   2172  C CG2 . THR A 1 289 ? -51.894 -26.898 40.164 1.00 53.02  ? 491 THR A CG2 1 
ATOM   2173  N N   . THR A 1 290 ? -53.996 -27.503 36.116 1.00 54.39  ? 492 THR A N   1 
ATOM   2174  C CA  . THR A 1 290 ? -54.601 -28.135 34.950 1.00 55.48  ? 492 THR A CA  1 
ATOM   2175  C C   . THR A 1 290 ? -53.903 -27.596 33.709 1.00 55.21  ? 492 THR A C   1 
ATOM   2176  O O   . THR A 1 290 ? -53.879 -26.383 33.482 1.00 55.33  ? 492 THR A O   1 
ATOM   2177  C CB  . THR A 1 290 ? -56.099 -27.857 34.905 1.00 52.98  ? 492 THR A CB  1 
ATOM   2178  O OG1 . THR A 1 290 ? -56.717 -28.375 36.089 1.00 55.34  ? 492 THR A OG1 1 
ATOM   2179  C CG2 . THR A 1 290 ? -56.722 -28.515 33.687 1.00 52.82  ? 492 THR A CG2 1 
ATOM   2180  N N   . VAL A 1 291 ? -53.337 -28.491 32.902 1.00 54.33  ? 493 VAL A N   1 
ATOM   2181  C CA  . VAL A 1 291 ? -52.494 -28.038 31.802 1.00 54.10  ? 493 VAL A CA  1 
ATOM   2182  C C   . VAL A 1 291 ? -53.311 -27.365 30.707 1.00 53.59  ? 493 VAL A C   1 
ATOM   2183  O O   . VAL A 1 291 ? -52.814 -26.459 30.033 1.00 53.46  ? 493 VAL A O   1 
ATOM   2184  C CB  . VAL A 1 291 ? -51.670 -29.211 31.247 1.00 54.92  ? 493 VAL A CB  1 
ATOM   2185  C CG1 . VAL A 1 291 ? -50.721 -29.725 32.308 1.00 56.58  ? 493 VAL A CG1 1 
ATOM   2186  C CG2 . VAL A 1 291 ? -52.584 -30.322 30.763 1.00 54.79  ? 493 VAL A CG2 1 
ATOM   2187  N N   . THR A 1 292 ? -54.566 -27.774 30.513 1.00 54.96  ? 494 THR A N   1 
ATOM   2188  C CA  . THR A 1 292 ? -55.373 -27.173 29.457 1.00 54.39  ? 494 THR A CA  1 
ATOM   2189  C C   . THR A 1 292 ? -55.632 -25.698 29.720 1.00 54.17  ? 494 THR A C   1 
ATOM   2190  O O   . THR A 1 292 ? -55.838 -24.926 28.777 1.00 54.28  ? 494 THR A O   1 
ATOM   2191  C CB  . THR A 1 292 ? -56.696 -27.923 29.311 1.00 58.06  ? 494 THR A CB  1 
ATOM   2192  O OG1 . THR A 1 292 ? -57.405 -27.890 30.554 1.00 58.32  ? 494 THR A OG1 1 
ATOM   2193  C CG2 . THR A 1 292 ? -56.445 -29.366 28.914 1.00 57.10  ? 494 THR A CG2 1 
ATOM   2194  N N   . GLN A 1 293 ? -55.584 -25.297 30.982 1.00 54.58  ? 495 GLN A N   1 
ATOM   2195  C CA  . GLN A 1 293 ? -55.820 -23.907 31.328 1.00 53.74  ? 495 GLN A CA  1 
ATOM   2196  C C   . GLN A 1 293 ? -54.626 -23.030 30.966 1.00 53.33  ? 495 GLN A C   1 
ATOM   2197  O O   . GLN A 1 293 ? -54.787 -21.855 30.666 1.00 53.75  ? 495 GLN A O   1 
ATOM   2198  C CB  . GLN A 1 293 ? -56.203 -23.778 32.802 1.00 51.03  ? 495 GLN A CB  1 
ATOM   2199  C CG  . GLN A 1 293 ? -57.472 -24.544 33.147 1.00 53.51  ? 495 GLN A CG  1 
ATOM   2200  C CD  . GLN A 1 293 ? -58.059 -24.171 34.495 1.00 55.38  ? 495 GLN A CD  1 
ATOM   2201  O OE1 . GLN A 1 293 ? -57.341 -23.840 35.431 1.00 57.16  ? 495 GLN A OE1 1 
ATOM   2202  N NE2 . GLN A 1 293 ? -59.378 -24.238 34.599 1.00 56.73  ? 495 GLN A NE2 1 
ATOM   2203  N N   . ASN A 1 294 ? -53.431 -23.607 30.998 1.00 51.47  ? 496 ASN A N   1 
ATOM   2204  C CA  . ASN A 1 294 ? -52.205 -22.894 30.660 1.00 50.79  ? 496 ASN A CA  1 
ATOM   2205  C C   . ASN A 1 294 ? -52.062 -22.650 29.165 1.00 51.33  ? 496 ASN A C   1 
ATOM   2206  O O   . ASN A 1 294 ? -52.607 -23.388 28.356 1.00 51.26  ? 496 ASN A O   1 
ATOM   2207  C CB  . ASN A 1 294 ? -50.988 -23.659 31.165 1.00 54.34  ? 496 ASN A CB  1 
ATOM   2208  C CG  . ASN A 1 294 ? -50.963 -23.780 32.667 1.00 54.37  ? 496 ASN A CG  1 
ATOM   2209  O OD1 . ASN A 1 294 ? -51.579 -22.991 33.373 1.00 53.11  ? 496 ASN A OD1 1 
ATOM   2210  N ND2 . ASN A 1 294 ? -50.247 -24.773 33.164 1.00 55.66  ? 496 ASN A ND2 1 
ATOM   2211  N N   . ASN A 1 295 ? -51.333 -21.602 28.802 1.00 52.58  ? 497 ASN A N   1 
ATOM   2212  C CA  . ASN A 1 295 ? -51.100 -21.284 27.400 1.00 53.34  ? 497 ASN A CA  1 
ATOM   2213  C C   . ASN A 1 295 ? -50.202 -22.332 26.749 1.00 54.22  ? 497 ASN A C   1 
ATOM   2214  O O   . ASN A 1 295 ? -49.287 -22.850 27.376 1.00 53.96  ? 497 ASN A O   1 
ATOM   2215  C CB  . ASN A 1 295 ? -50.481 -19.895 27.260 1.00 49.87  ? 497 ASN A CB  1 
ATOM   2216  C CG  . ASN A 1 295 ? -50.467 -19.409 25.831 1.00 51.10  ? 497 ASN A CG  1 
ATOM   2217  O OD1 . ASN A 1 295 ? -49.816 -19.990 24.975 1.00 51.54  ? 497 ASN A OD1 1 
ATOM   2218  N ND2 . ASN A 1 295 ? -51.186 -18.335 25.568 1.00 51.34  ? 497 ASN A ND2 1 
ATOM   2219  N N   . ASN A 1 296 ? -50.467 -22.640 25.486 1.00 53.63  ? 498 ASN A N   1 
ATOM   2220  C CA  . ASN A 1 296 ? -49.691 -23.630 24.759 1.00 54.78  ? 498 ASN A CA  1 
ATOM   2221  C C   . ASN A 1 296 ? -48.430 -23.046 24.135 1.00 55.49  ? 498 ASN A C   1 
ATOM   2222  O O   . ASN A 1 296 ? -48.317 -22.945 22.918 1.00 56.05  ? 498 ASN A O   1 
ATOM   2223  C CB  . ASN A 1 296 ? -50.559 -24.262 23.673 1.00 57.67  ? 498 ASN A CB  1 
ATOM   2224  C CG  . ASN A 1 296 ? -49.787 -25.207 22.786 1.00 57.78  ? 498 ASN A CG  1 
ATOM   2225  O OD1 . ASN A 1 296 ? -48.914 -25.933 23.245 1.00 57.49  ? 498 ASN A OD1 1 
ATOM   2226  N ND2 . ASN A 1 296 ? -50.101 -25.196 21.502 1.00 58.74  ? 498 ASN A ND2 1 
ATOM   2227  N N   . SER A 1 297 ? -47.471 -22.676 24.974 1.00 49.00  ? 499 SER A N   1 
ATOM   2228  C CA  . SER A 1 297 ? -46.199 -22.139 24.505 1.00 49.88  ? 499 SER A CA  1 
ATOM   2229  C C   . SER A 1 297 ? -45.184 -22.246 25.624 1.00 50.03  ? 499 SER A C   1 
ATOM   2230  O O   . SER A 1 297 ? -45.545 -22.492 26.768 1.00 49.71  ? 499 SER A O   1 
ATOM   2231  C CB  . SER A 1 297 ? -46.334 -20.685 24.059 1.00 48.06  ? 499 SER A CB  1 
ATOM   2232  O OG  . SER A 1 297 ? -46.400 -19.808 25.166 1.00 48.95  ? 499 SER A OG  1 
ATOM   2233  N N   . GLU A 1 298 ? -43.911 -22.049 25.310 1.00 44.50  ? 500 GLU A N   1 
ATOM   2234  C CA  . GLU A 1 298 ? -42.894 -22.137 26.345 1.00 45.01  ? 500 GLU A CA  1 
ATOM   2235  C C   . GLU A 1 298 ? -42.723 -20.769 26.968 1.00 44.24  ? 500 GLU A C   1 
ATOM   2236  O O   . GLU A 1 298 ? -42.173 -19.866 26.351 1.00 44.65  ? 500 GLU A O   1 
ATOM   2237  C CB  . GLU A 1 298 ? -41.570 -22.592 25.749 1.00 40.52  ? 500 GLU A CB  1 
ATOM   2238  C CG  . GLU A 1 298 ? -40.442 -22.649 26.757 1.00 44.59  ? 500 GLU A CG  1 
ATOM   2239  C CD  . GLU A 1 298 ? -40.653 -23.720 27.805 1.00 46.95  ? 500 GLU A CD  1 
ATOM   2240  O OE1 . GLU A 1 298 ? -40.869 -24.893 27.438 1.00 48.21  ? 500 GLU A OE1 1 
ATOM   2241  O OE2 . GLU A 1 298 ? -40.593 -23.390 29.002 1.00 47.06  ? 500 GLU A OE2 1 
ATOM   2242  N N   . PHE A 1 299 ? -43.229 -20.617 28.185 1.00 40.32  ? 501 PHE A N   1 
ATOM   2243  C CA  . PHE A 1 299 ? -43.137 -19.356 28.901 1.00 39.25  ? 501 PHE A CA  1 
ATOM   2244  C C   . PHE A 1 299 ? -42.426 -19.449 30.242 1.00 38.79  ? 501 PHE A C   1 
ATOM   2245  O O   . PHE A 1 299 ? -42.442 -18.498 31.009 1.00 39.01  ? 501 PHE A O   1 
ATOM   2246  C CB  . PHE A 1 299 ? -44.528 -18.747 29.088 1.00 44.95  ? 501 PHE A CB  1 
ATOM   2247  C CG  . PHE A 1 299 ? -45.446 -19.570 29.945 1.00 44.12  ? 501 PHE A CG  1 
ATOM   2248  C CD1 . PHE A 1 299 ? -45.418 -19.457 31.321 1.00 43.74  ? 501 PHE A CD1 1 
ATOM   2249  C CD2 . PHE A 1 299 ? -46.347 -20.445 29.372 1.00 43.80  ? 501 PHE A CD2 1 
ATOM   2250  C CE1 . PHE A 1 299 ? -46.263 -20.209 32.108 1.00 43.27  ? 501 PHE A CE1 1 
ATOM   2251  C CE2 . PHE A 1 299 ? -47.195 -21.201 30.153 1.00 43.20  ? 501 PHE A CE2 1 
ATOM   2252  C CZ  . PHE A 1 299 ? -47.153 -21.084 31.524 1.00 42.93  ? 501 PHE A CZ  1 
ATOM   2253  N N   . ALA A 1 300 ? -41.785 -20.576 30.525 1.00 38.67  ? 502 ALA A N   1 
ATOM   2254  C CA  . ALA A 1 300 ? -41.138 -20.746 31.822 1.00 37.72  ? 502 ALA A CA  1 
ATOM   2255  C C   . ALA A 1 300 ? -40.032 -19.740 32.092 1.00 37.53  ? 502 ALA A C   1 
ATOM   2256  O O   . ALA A 1 300 ? -39.914 -19.240 33.200 1.00 37.45  ? 502 ALA A O   1 
ATOM   2257  C CB  . ALA A 1 300 ? -40.615 -22.163 31.976 1.00 41.15  ? 502 ALA A CB  1 
ATOM   2258  N N   . TRP A 1 301 ? -39.197 -19.467 31.100 1.00 34.92  ? 503 TRP A N   1 
ATOM   2259  C CA  . TRP A 1 301 ? -38.144 -18.487 31.292 1.00 35.46  ? 503 TRP A CA  1 
ATOM   2260  C C   . TRP A 1 301 ? -38.552 -17.132 30.732 1.00 35.14  ? 503 TRP A C   1 
ATOM   2261  O O   . TRP A 1 301 ? -38.338 -16.104 31.365 1.00 35.12  ? 503 TRP A O   1 
ATOM   2262  C CB  . TRP A 1 301 ? -36.830 -18.951 30.671 1.00 29.53  ? 503 TRP A CB  1 
ATOM   2263  C CG  . TRP A 1 301 ? -35.758 -17.926 30.795 1.00 32.80  ? 503 TRP A CG  1 
ATOM   2264  C CD1 . TRP A 1 301 ? -35.154 -17.252 29.782 1.00 33.66  ? 503 TRP A CD1 1 
ATOM   2265  C CD2 . TRP A 1 301 ? -35.178 -17.435 32.007 1.00 34.38  ? 503 TRP A CD2 1 
ATOM   2266  N NE1 . TRP A 1 301 ? -34.226 -16.378 30.284 1.00 34.30  ? 503 TRP A NE1 1 
ATOM   2267  C CE2 . TRP A 1 301 ? -34.222 -16.470 31.649 1.00 34.66  ? 503 TRP A CE2 1 
ATOM   2268  C CE3 . TRP A 1 301 ? -35.373 -17.719 33.359 1.00 35.15  ? 503 TRP A CE3 1 
ATOM   2269  C CZ2 . TRP A 1 301 ? -33.462 -15.790 32.591 1.00 35.44  ? 503 TRP A CZ2 1 
ATOM   2270  C CZ3 . TRP A 1 301 ? -34.618 -17.043 34.293 1.00 35.76  ? 503 TRP A CZ3 1 
ATOM   2271  C CH2 . TRP A 1 301 ? -33.676 -16.089 33.905 1.00 35.96  ? 503 TRP A CH2 1 
ATOM   2272  N N   . PRO A 1 302 ? -39.158 -17.131 29.542 1.00 35.80  ? 504 PRO A N   1 
ATOM   2273  C CA  . PRO A 1 302 ? -39.608 -15.908 28.877 1.00 35.53  ? 504 PRO A CA  1 
ATOM   2274  C C   . PRO A 1 302 ? -40.683 -15.165 29.663 1.00 35.97  ? 504 PRO A C   1 
ATOM   2275  O O   . PRO A 1 302 ? -40.661 -13.939 29.709 1.00 37.54  ? 504 PRO A O   1 
ATOM   2276  C CB  . PRO A 1 302 ? -40.181 -16.424 27.560 1.00 35.41  ? 504 PRO A CB  1 
ATOM   2277  C CG  . PRO A 1 302 ? -39.461 -17.700 27.317 1.00 34.73  ? 504 PRO A CG  1 
ATOM   2278  C CD  . PRO A 1 302 ? -39.281 -18.308 28.671 1.00 36.13  ? 504 PRO A CD  1 
ATOM   2279  N N   . GLY A 1 303 ? -41.616 -15.897 30.259 1.00 37.99  ? 505 GLY A N   1 
ATOM   2280  C CA  . GLY A 1 303 ? -42.688 -15.289 31.021 1.00 38.29  ? 505 GLY A CA  1 
ATOM   2281  C C   . GLY A 1 303 ? -42.362 -15.059 32.480 1.00 37.93  ? 505 GLY A C   1 
ATOM   2282  O O   . GLY A 1 303 ? -43.169 -14.514 33.223 1.00 38.86  ? 505 GLY A O   1 
ATOM   2283  N N   . ALA A 1 304 ? -41.188 -15.504 32.901 1.00 35.55  ? 506 ALA A N   1 
ATOM   2284  C CA  . ALA A 1 304 ? -40.756 -15.361 34.286 1.00 34.32  ? 506 ALA A CA  1 
ATOM   2285  C C   . ALA A 1 304 ? -40.341 -13.958 34.720 1.00 33.65  ? 506 ALA A C   1 
ATOM   2286  O O   . ALA A 1 304 ? -39.708 -13.229 33.971 1.00 34.50  ? 506 ALA A O   1 
ATOM   2287  C CB  . ALA A 1 304 ? -39.635 -16.344 34.578 1.00 29.61  ? 506 ALA A CB  1 
ATOM   2288  N N   . SER A 1 305 ? -40.716 -13.591 35.941 1.00 32.52  ? 507 SER A N   1 
ATOM   2289  C CA  . SER A 1 305 ? -40.328 -12.320 36.525 1.00 31.36  ? 507 SER A CA  1 
ATOM   2290  C C   . SER A 1 305 ? -38.859 -12.448 36.863 1.00 30.31  ? 507 SER A C   1 
ATOM   2291  O O   . SER A 1 305 ? -38.415 -13.516 37.260 1.00 29.81  ? 507 SER A O   1 
ATOM   2292  C CB  . SER A 1 305 ? -41.113 -12.059 37.802 1.00 32.90  ? 507 SER A CB  1 
ATOM   2293  O OG  . SER A 1 305 ? -42.501 -12.068 37.554 1.00 34.89  ? 507 SER A OG  1 
ATOM   2294  N N   . SER A 1 306 ? -38.092 -11.379 36.734 1.00 27.31  ? 508 SER A N   1 
ATOM   2295  C CA  . SER A 1 306 ? -36.677 -11.489 37.043 1.00 26.37  ? 508 SER A CA  1 
ATOM   2296  C C   . SER A 1 306 ? -36.039 -10.183 37.435 1.00 25.56  ? 508 SER A C   1 
ATOM   2297  O O   . SER A 1 306 ? -36.688 -9.153  37.510 1.00 26.09  ? 508 SER A O   1 
ATOM   2298  C CB  . SER A 1 306 ? -35.922 -12.058 35.840 1.00 28.05  ? 508 SER A CB  1 
ATOM   2299  O OG  . SER A 1 306 ? -36.072 -11.233 34.701 1.00 28.14  ? 508 SER A OG  1 
ATOM   2300  N N   . TRP A 1 307 ? -34.753 -10.249 37.728 1.00 22.54  ? 509 TRP A N   1 
ATOM   2301  C CA  . TRP A 1 307 ? -33.999 -9.046  38.033 1.00 21.98  ? 509 TRP A CA  1 
ATOM   2302  C C   . TRP A 1 307 ? -32.618 -9.139  37.404 1.00 21.56  ? 509 TRP A C   1 
ATOM   2303  O O   . TRP A 1 307 ? -32.013 -10.211 37.350 1.00 19.95  ? 509 TRP A O   1 
ATOM   2304  C CB  . TRP A 1 307 ? -33.884 -8.803  39.541 1.00 19.42  ? 509 TRP A CB  1 
ATOM   2305  C CG  . TRP A 1 307 ? -33.377 -9.959  40.346 1.00 20.09  ? 509 TRP A CG  1 
ATOM   2306  C CD1 . TRP A 1 307 ? -34.126 -10.919 40.951 1.00 20.55  ? 509 TRP A CD1 1 
ATOM   2307  C CD2 . TRP A 1 307 ? -32.013 -10.269 40.642 1.00 20.46  ? 509 TRP A CD2 1 
ATOM   2308  N NE1 . TRP A 1 307 ? -33.318 -11.807 41.610 1.00 21.14  ? 509 TRP A NE1 1 
ATOM   2309  C CE2 . TRP A 1 307 ? -32.013 -11.432 41.433 1.00 21.06  ? 509 TRP A CE2 1 
ATOM   2310  C CE3 . TRP A 1 307 ? -30.791 -9.683  40.308 1.00 20.90  ? 509 TRP A CE3 1 
ATOM   2311  C CZ2 . TRP A 1 307 ? -30.842 -12.015 41.901 1.00 21.58  ? 509 TRP A CZ2 1 
ATOM   2312  C CZ3 . TRP A 1 307 ? -29.630 -10.260 40.778 1.00 21.66  ? 509 TRP A CZ3 1 
ATOM   2313  C CH2 . TRP A 1 307 ? -29.663 -11.415 41.563 1.00 22.23  ? 509 TRP A CH2 1 
ATOM   2314  N N   . ALA A 1 308 ? -32.132 -8.001  36.922 1.00 19.90  ? 510 ALA A N   1 
ATOM   2315  C CA  . ALA A 1 308 ? -30.886 -7.928  36.177 1.00 20.25  ? 510 ALA A CA  1 
ATOM   2316  C C   . ALA A 1 308 ? -29.778 -7.361  37.050 1.00 21.23  ? 510 ALA A C   1 
ATOM   2317  O O   . ALA A 1 308 ? -29.972 -6.362  37.746 1.00 22.46  ? 510 ALA A O   1 
ATOM   2318  C CB  . ALA A 1 308 ? -31.045 -7.070  34.922 1.00 22.84  ? 510 ALA A CB  1 
ATOM   2319  N N   . LEU A 1 309 ? -28.621 -8.015  37.017 1.00 18.64  ? 511 LEU A N   1 
ATOM   2320  C CA  . LEU A 1 309 ? -27.432 -7.539  37.711 1.00 19.22  ? 511 LEU A CA  1 
ATOM   2321  C C   . LEU A 1 309 ? -26.250 -7.652  36.763 1.00 20.39  ? 511 LEU A C   1 
ATOM   2322  O O   . LEU A 1 309 ? -25.864 -8.764  36.392 1.00 20.20  ? 511 LEU A O   1 
ATOM   2323  C CB  . LEU A 1 309 ? -27.183 -8.352  38.981 1.00 17.57  ? 511 LEU A CB  1 
ATOM   2324  C CG  . LEU A 1 309 ? -25.956 -8.030  39.824 1.00 17.63  ? 511 LEU A CG  1 
ATOM   2325  C CD1 . LEU A 1 309 ? -26.067 -6.640  40.408 1.00 17.80  ? 511 LEU A CD1 1 
ATOM   2326  C CD2 . LEU A 1 309 ? -25.808 -9.062  40.913 1.00 17.49  ? 511 LEU A CD2 1 
ATOM   2327  N N   . ASN A 1 310 ? -25.678 -6.512  36.380 1.00 18.77  ? 512 ASN A N   1 
ATOM   2328  C CA  . ASN A 1 310 ? -24.489 -6.472  35.529 1.00 20.60  ? 512 ASN A CA  1 
ATOM   2329  C C   . ASN A 1 310 ? -24.696 -7.251  34.231 1.00 21.25  ? 512 ASN A C   1 
ATOM   2330  O O   . ASN A 1 310 ? -23.858 -8.056  33.820 1.00 21.76  ? 512 ASN A O   1 
ATOM   2331  C CB  . ASN A 1 310 ? -23.266 -6.985  36.287 1.00 21.33  ? 512 ASN A CB  1 
ATOM   2332  C CG  . ASN A 1 310 ? -21.973 -6.720  35.556 1.00 23.60  ? 512 ASN A CG  1 
ATOM   2333  O OD1 . ASN A 1 310 ? -21.865 -5.762  34.797 1.00 25.55  ? 512 ASN A OD1 1 
ATOM   2334  N ND2 . ASN A 1 310 ? -20.981 -7.566  35.784 1.00 22.93  ? 512 ASN A ND2 1 
ATOM   2335  N N   . GLY A 1 311 ? -25.826 -7.011  33.575 1.00 21.36  ? 513 GLY A N   1 
ATOM   2336  C CA  . GLY A 1 311 ? -26.108 -7.625  32.299 1.00 21.34  ? 513 GLY A CA  1 
ATOM   2337  C C   . GLY A 1 311 ? -26.589 -9.058  32.358 1.00 22.18  ? 513 GLY A C   1 
ATOM   2338  O O   . GLY A 1 311 ? -26.976 -9.604  31.318 1.00 23.48  ? 513 GLY A O   1 
ATOM   2339  N N   . ARG A 1 312 ? -26.571 -9.688  33.527 1.00 23.36  ? 514 ARG A N   1 
ATOM   2340  C CA  . ARG A 1 312 ? -27.072 -11.041 33.706 1.00 23.75  ? 514 ARG A CA  1 
ATOM   2341  C C   . ARG A 1 312 ? -28.461 -11.003 34.325 1.00 23.50  ? 514 ARG A C   1 
ATOM   2342  O O   . ARG A 1 312 ? -28.736 -10.203 35.222 1.00 24.02  ? 514 ARG A O   1 
ATOM   2343  C CB  . ARG A 1 312 ? -26.137 -11.866 34.593 1.00 20.82  ? 514 ARG A CB  1 
ATOM   2344  C CG  . ARG A 1 312 ? -24.817 -12.217 33.953 1.00 24.82  ? 514 ARG A CG  1 
ATOM   2345  C CD  . ARG A 1 312 ? -23.878 -12.849 34.961 1.00 28.87  ? 514 ARG A CD  1 
ATOM   2346  N NE  . ARG A 1 312 ? -23.515 -11.903 36.008 1.00 33.06  ? 514 ARG A NE  1 
ATOM   2347  C CZ  . ARG A 1 312 ? -22.695 -12.181 37.013 1.00 35.48  ? 514 ARG A CZ  1 
ATOM   2348  N NH1 . ARG A 1 312 ? -22.152 -13.384 37.109 1.00 36.12  ? 514 ARG A NH1 1 
ATOM   2349  N NH2 . ARG A 1 312 ? -22.417 -11.258 37.921 1.00 36.49  ? 514 ARG A NH2 1 
ATOM   2350  N N   . ASN A 1 313 ? -29.333 -11.878 33.840 1.00 25.26  ? 515 ASN A N   1 
ATOM   2351  C CA  . ASN A 1 313 ? -30.705 -11.958 34.315 1.00 24.47  ? 515 ASN A CA  1 
ATOM   2352  C C   . ASN A 1 313 ? -30.851 -13.138 35.263 1.00 23.06  ? 515 ASN A C   1 
ATOM   2353  O O   . ASN A 1 313 ? -30.587 -14.282 34.883 1.00 23.26  ? 515 ASN A O   1 
ATOM   2354  C CB  . ASN A 1 313 ? -31.681 -12.104 33.151 1.00 25.04  ? 515 ASN A CB  1 
ATOM   2355  C CG  . ASN A 1 313 ? -31.766 -10.859 32.309 1.00 26.65  ? 515 ASN A CG  1 
ATOM   2356  O OD1 . ASN A 1 313 ? -32.386 -9.875  32.700 1.00 27.51  ? 515 ASN A OD1 1 
ATOM   2357  N ND2 . ASN A 1 313 ? -31.148 -10.897 31.138 1.00 28.51  ? 515 ASN A ND2 1 
ATOM   2358  N N   . SER A 1 314 ? -31.305 -12.860 36.480 1.00 25.66  ? 516 SER A N   1 
ATOM   2359  C CA  . SER A 1 314 ? -31.536 -13.890 37.480 1.00 24.69  ? 516 SER A CA  1 
ATOM   2360  C C   . SER A 1 314 ? -33.030 -13.968 37.706 1.00 24.35  ? 516 SER A C   1 
ATOM   2361  O O   . SER A 1 314 ? -33.682 -12.947 37.848 1.00 24.01  ? 516 SER A O   1 
ATOM   2362  C CB  . SER A 1 314 ? -30.866 -13.537 38.806 1.00 22.74  ? 516 SER A CB  1 
ATOM   2363  O OG  . SER A 1 314 ? -29.561 -13.026 38.623 1.00 24.12  ? 516 SER A OG  1 
ATOM   2364  N N   . LEU A 1 315 ? -33.577 -15.173 37.735 1.00 25.02  ? 517 LEU A N   1 
ATOM   2365  C CA  . LEU A 1 315 ? -35.002 -15.350 37.960 1.00 25.33  ? 517 LEU A CA  1 
ATOM   2366  C C   . LEU A 1 315 ? -35.339 -14.869 39.352 1.00 25.76  ? 517 LEU A C   1 
ATOM   2367  O O   . LEU A 1 315 ? -34.586 -15.112 40.279 1.00 26.61  ? 517 LEU A O   1 
ATOM   2368  C CB  . LEU A 1 315 ? -35.368 -16.822 37.852 1.00 29.81  ? 517 LEU A CB  1 
ATOM   2369  C CG  . LEU A 1 315 ? -36.849 -17.178 37.813 1.00 30.58  ? 517 LEU A CG  1 
ATOM   2370  C CD1 . LEU A 1 315 ? -37.296 -17.235 36.367 1.00 30.39  ? 517 LEU A CD1 1 
ATOM   2371  C CD2 . LEU A 1 315 ? -37.076 -18.519 38.484 1.00 32.43  ? 517 LEU A CD2 1 
ATOM   2372  N N   . MET A 1 316 ? -36.487 -14.220 39.513 1.00 30.89  ? 518 MET A N   1 
ATOM   2373  C CA  . MET A 1 316 ? -36.904 -13.727 40.817 1.00 30.80  ? 518 MET A CA  1 
ATOM   2374  C C   . MET A 1 316 ? -37.575 -14.868 41.559 1.00 30.60  ? 518 MET A C   1 
ATOM   2375  O O   . MET A 1 316 ? -38.792 -14.977 41.595 1.00 30.42  ? 518 MET A O   1 
ATOM   2376  C CB  . MET A 1 316 ? -37.875 -12.563 40.658 1.00 26.40  ? 518 MET A CB  1 
ATOM   2377  C CG  . MET A 1 316 ? -38.418 -12.020 41.965 1.00 27.76  ? 518 MET A CG  1 
ATOM   2378  S SD  . MET A 1 316 ? -37.276 -10.924 42.821 1.00 30.45  ? 518 MET A SD  1 
ATOM   2379  C CE  . MET A 1 316 ? -37.063 -9.642  41.598 1.00 28.21  ? 518 MET A CE  1 
ATOM   2380  N N   . ASN A 1 317 ? -36.751 -15.719 42.148 1.00 37.02  ? 519 ASN A N   1 
ATOM   2381  C CA  . ASN A 1 317 ? -37.191 -16.893 42.870 1.00 36.43  ? 519 ASN A CA  1 
ATOM   2382  C C   . ASN A 1 317 ? -36.680 -16.805 44.296 1.00 36.21  ? 519 ASN A C   1 
ATOM   2383  O O   . ASN A 1 317 ? -35.501 -16.573 44.508 1.00 36.99  ? 519 ASN A O   1 
ATOM   2384  C CB  . ASN A 1 317 ? -36.596 -18.115 42.170 1.00 37.68  ? 519 ASN A CB  1 
ATOM   2385  C CG  . ASN A 1 317 ? -37.063 -19.425 42.757 1.00 38.12  ? 519 ASN A CG  1 
ATOM   2386  O OD1 . ASN A 1 317 ? -38.025 -19.478 43.515 1.00 40.47  ? 519 ASN A OD1 1 
ATOM   2387  N ND2 . ASN A 1 317 ? -36.379 -20.500 42.395 1.00 36.86  ? 519 ASN A ND2 1 
ATOM   2388  N N   . PRO A 1 318 ? -37.554 -17.020 45.287 1.00 39.77  ? 520 PRO A N   1 
ATOM   2389  C CA  . PRO A 1 318 ? -38.995 -16.757 45.367 1.00 39.58  ? 520 PRO A CA  1 
ATOM   2390  C C   . PRO A 1 318 ? -39.352 -15.272 45.287 1.00 40.12  ? 520 PRO A C   1 
ATOM   2391  O O   . PRO A 1 318 ? -40.363 -14.928 44.688 1.00 39.88  ? 520 PRO A O   1 
ATOM   2392  C CB  . PRO A 1 318 ? -39.383 -17.333 46.730 1.00 39.05  ? 520 PRO A CB  1 
ATOM   2393  C CG  . PRO A 1 318 ? -38.127 -17.319 47.517 1.00 39.06  ? 520 PRO A CG  1 
ATOM   2394  C CD  . PRO A 1 318 ? -37.044 -17.617 46.530 1.00 39.88  ? 520 PRO A CD  1 
ATOM   2395  N N   . GLY A 1 319 ? -38.546 -14.411 45.898 1.00 38.07  ? 521 GLY A N   1 
ATOM   2396  C CA  . GLY A 1 319 ? -38.818 -12.987 45.890 1.00 39.09  ? 521 GLY A CA  1 
ATOM   2397  C C   . GLY A 1 319 ? -39.695 -12.597 47.058 1.00 39.91  ? 521 GLY A C   1 
ATOM   2398  O O   . GLY A 1 319 ? -39.906 -13.394 47.963 1.00 40.40  ? 521 GLY A O   1 
ATOM   2399  N N   . PRO A 1 320 ? -40.209 -11.362 47.052 1.00 39.86  ? 522 PRO A N   1 
ATOM   2400  C CA  . PRO A 1 320 ? -41.068 -10.834 48.119 1.00 39.59  ? 522 PRO A CA  1 
ATOM   2401  C C   . PRO A 1 320 ? -42.182 -11.790 48.559 1.00 39.30  ? 522 PRO A C   1 
ATOM   2402  O O   . PRO A 1 320 ? -42.831 -12.427 47.735 1.00 40.38  ? 522 PRO A O   1 
ATOM   2403  C CB  . PRO A 1 320 ? -41.667 -9.578  47.486 1.00 34.46  ? 522 PRO A CB  1 
ATOM   2404  C CG  . PRO A 1 320 ? -40.651 -9.147  46.490 1.00 35.78  ? 522 PRO A CG  1 
ATOM   2405  C CD  . PRO A 1 320 ? -40.044 -10.405 45.947 1.00 35.20  ? 522 PRO A CD  1 
ATOM   2406  N N   . ALA A 1 321 ? -42.406 -11.867 49.864 1.00 41.77  ? 523 ALA A N   1 
ATOM   2407  C CA  . ALA A 1 321 ? -43.429 -12.741 50.422 1.00 41.57  ? 523 ALA A CA  1 
ATOM   2408  C C   . ALA A 1 321 ? -44.805 -12.237 50.013 1.00 41.68  ? 523 ALA A C   1 
ATOM   2409  O O   . ALA A 1 321 ? -45.170 -11.094 50.306 1.00 41.37  ? 523 ALA A O   1 
ATOM   2410  C CB  . ALA A 1 321 ? -43.310 -12.807 51.942 1.00 38.32  ? 523 ALA A CB  1 
ATOM   2411  N N   . MET A 1 322 ? -45.566 -13.093 49.337 1.00 39.84  ? 524 MET A N   1 
ATOM   2412  C CA  . MET A 1 322 ? -46.906 -12.770 48.874 1.00 40.67  ? 524 MET A CA  1 
ATOM   2413  C C   . MET A 1 322 ? -47.752 -14.031 48.903 1.00 41.09  ? 524 MET A C   1 
ATOM   2414  O O   . MET A 1 322 ? -47.230 -15.146 48.842 1.00 42.68  ? 524 MET A O   1 
ATOM   2415  C CB  . MET A 1 322 ? -46.889 -12.190 47.456 1.00 37.05  ? 524 MET A CB  1 
ATOM   2416  C CG  . MET A 1 322 ? -46.247 -10.825 47.341 1.00 39.75  ? 524 MET A CG  1 
ATOM   2417  S SD  . MET A 1 322 ? -46.245 -10.226 45.649 1.00 43.34  ? 524 MET A SD  1 
ATOM   2418  C CE  . MET A 1 322 ? -44.970 -11.268 44.960 1.00 45.42  ? 524 MET A CE  1 
ATOM   2419  N N   . ALA A 1 323 ? -49.065 -13.847 48.993 1.00 43.40  ? 525 ALA A N   1 
ATOM   2420  C CA  . ALA A 1 323 ? -49.970 -14.985 48.955 1.00 44.40  ? 525 ALA A CA  1 
ATOM   2421  C C   . ALA A 1 323 ? -49.925 -15.645 47.583 1.00 45.77  ? 525 ALA A C   1 
ATOM   2422  O O   . ALA A 1 323 ? -49.947 -14.972 46.550 1.00 46.23  ? 525 ALA A O   1 
ATOM   2423  C CB  . ALA A 1 323 ? -51.395 -14.546 49.287 1.00 48.06  ? 525 ALA A CB  1 
ATOM   2424  N N   . SER A 1 324 ? -49.857 -16.977 47.581 1.00 48.98  ? 526 SER A N   1 
ATOM   2425  C CA  . SER A 1 324 ? -49.716 -17.709 46.327 1.00 50.77  ? 526 SER A CA  1 
ATOM   2426  C C   . SER A 1 324 ? -50.980 -17.642 45.483 1.00 51.94  ? 526 SER A C   1 
ATOM   2427  O O   . SER A 1 324 ? -50.902 -17.669 44.251 1.00 52.09  ? 526 SER A O   1 
ATOM   2428  C CB  . SER A 1 324 ? -49.351 -19.166 46.611 1.00 52.64  ? 526 SER A CB  1 
ATOM   2429  O OG  . SER A 1 324 ? -48.087 -19.264 47.244 1.00 55.37  ? 526 SER A OG  1 
ATOM   2430  N N   . HIS A 1 325 ? -52.136 -17.544 46.120 1.00 53.97  ? 527 HIS A N   1 
ATOM   2431  C CA  . HIS A 1 325 ? -53.376 -17.497 45.370 1.00 56.45  ? 527 HIS A CA  1 
ATOM   2432  C C   . HIS A 1 325 ? -54.474 -16.844 46.176 1.00 57.99  ? 527 HIS A C   1 
ATOM   2433  O O   . HIS A 1 325 ? -54.394 -16.765 47.397 1.00 58.01  ? 527 HIS A O   1 
ATOM   2434  C CB  . HIS A 1 325 ? -53.803 -18.915 45.021 1.00 61.21  ? 527 HIS A CB  1 
ATOM   2435  C CG  . HIS A 1 325 ? -53.931 -19.805 46.215 1.00 62.03  ? 527 HIS A CG  1 
ATOM   2436  N ND1 . HIS A 1 325 ? -54.992 -19.727 47.090 1.00 62.59  ? 527 HIS A ND1 1 
ATOM   2437  C CD2 . HIS A 1 325 ? -53.128 -20.785 46.688 1.00 62.06  ? 527 HIS A CD2 1 
ATOM   2438  C CE1 . HIS A 1 325 ? -54.839 -20.621 48.048 1.00 61.65  ? 527 HIS A CE1 1 
ATOM   2439  N NE2 . HIS A 1 325 ? -53.716 -21.278 47.827 1.00 61.59  ? 527 HIS A NE2 1 
ATOM   2440  N N   . LYS A 1 326 ? -55.501 -16.368 45.483 1.00 60.58  ? 528 LYS A N   1 
ATOM   2441  C CA  . LYS A 1 326 ? -56.645 -15.755 46.140 1.00 63.34  ? 528 LYS A CA  1 
ATOM   2442  C C   . LYS A 1 326 ? -57.441 -16.850 46.831 1.00 65.34  ? 528 LYS A C   1 
ATOM   2443  O O   . LYS A 1 326 ? -57.472 -17.986 46.363 1.00 64.86  ? 528 LYS A O   1 
ATOM   2444  C CB  . LYS A 1 326 ? -57.514 -15.004 45.133 1.00 59.31  ? 528 LYS A CB  1 
ATOM   2445  C CG  . LYS A 1 326 ? -57.040 -13.588 44.859 1.00 59.91  ? 528 LYS A CG  1 
ATOM   2446  C CD  . LYS A 1 326 ? -57.911 -12.888 43.832 1.00 62.09  ? 528 LYS A CD  1 
ATOM   2447  C CE  . LYS A 1 326 ? -57.698 -13.466 42.446 1.00 62.49  ? 528 LYS A CE  1 
ATOM   2448  N NZ  . LYS A 1 326 ? -58.453 -12.706 41.416 1.00 62.89  ? 528 LYS A NZ  1 
ATOM   2449  N N   . GLU A 1 327 ? -58.108 -16.517 47.928 1.00 64.54  ? 529 GLU A N   1 
ATOM   2450  C CA  . GLU A 1 327 ? -58.868 -17.526 48.653 1.00 68.26  ? 529 GLU A CA  1 
ATOM   2451  C C   . GLU A 1 327 ? -59.966 -18.097 47.772 1.00 68.97  ? 529 GLU A C   1 
ATOM   2452  O O   . GLU A 1 327 ? -60.610 -17.379 47.011 1.00 69.01  ? 529 GLU A O   1 
ATOM   2453  C CB  . GLU A 1 327 ? -59.451 -16.955 49.944 1.00 66.04  ? 529 GLU A CB  1 
ATOM   2454  C CG  . GLU A 1 327 ? -60.171 -17.978 50.805 1.00 71.82  ? 529 GLU A CG  1 
ATOM   2455  C CD  . GLU A 1 327 ? -60.083 -17.662 52.283 1.00 74.83  ? 529 GLU A CD  1 
ATOM   2456  O OE1 . GLU A 1 327 ? -59.962 -18.611 53.086 1.00 75.22  ? 529 GLU A OE1 1 
ATOM   2457  O OE2 . GLU A 1 327 ? -60.124 -16.469 52.641 1.00 76.78  ? 529 GLU A OE2 1 
ATOM   2458  N N   . GLY A 1 328 ? -60.172 -19.403 47.888 1.00 68.97  ? 530 GLY A N   1 
ATOM   2459  C CA  . GLY A 1 328 ? -61.165 -20.106 47.102 1.00 69.70  ? 530 GLY A CA  1 
ATOM   2460  C C   . GLY A 1 328 ? -60.608 -20.644 45.802 1.00 70.19  ? 530 GLY A C   1 
ATOM   2461  O O   . GLY A 1 328 ? -61.318 -21.299 45.042 1.00 71.15  ? 530 GLY A O   1 
ATOM   2462  N N   . GLU A 1 329 ? -59.336 -20.370 45.539 1.00 69.02  ? 531 GLU A N   1 
ATOM   2463  C CA  . GLU A 1 329 ? -58.694 -20.878 44.338 1.00 68.54  ? 531 GLU A CA  1 
ATOM   2464  C C   . GLU A 1 329 ? -57.556 -21.779 44.781 1.00 66.84  ? 531 GLU A C   1 
ATOM   2465  O O   . GLU A 1 329 ? -56.664 -21.345 45.498 1.00 66.82  ? 531 GLU A O   1 
ATOM   2466  C CB  . GLU A 1 329 ? -58.150 -19.728 43.493 1.00 63.63  ? 531 GLU A CB  1 
ATOM   2467  C CG  . GLU A 1 329 ? -59.183 -18.672 43.146 1.00 67.68  ? 531 GLU A CG  1 
ATOM   2468  C CD  . GLU A 1 329 ? -58.629 -17.595 42.234 1.00 71.22  ? 531 GLU A CD  1 
ATOM   2469  O OE1 . GLU A 1 329 ? -57.396 -17.539 42.056 1.00 73.39  ? 531 GLU A OE1 1 
ATOM   2470  O OE2 . GLU A 1 329 ? -59.427 -16.803 41.693 1.00 72.21  ? 531 GLU A OE2 1 
ATOM   2471  N N   . ASP A 1 330 ? -57.582 -23.037 44.364 1.00 65.08  ? 532 ASP A N   1 
ATOM   2472  C CA  . ASP A 1 330 ? -56.526 -23.959 44.752 1.00 63.43  ? 532 ASP A CA  1 
ATOM   2473  C C   . ASP A 1 330 ? -55.697 -24.492 43.588 1.00 60.24  ? 532 ASP A C   1 
ATOM   2474  O O   . ASP A 1 330 ? -54.651 -25.095 43.797 1.00 59.22  ? 532 ASP A O   1 
ATOM   2475  C CB  . ASP A 1 330 ? -57.114 -25.112 45.569 1.00 61.64  ? 532 ASP A CB  1 
ATOM   2476  C CG  . ASP A 1 330 ? -58.560 -25.401 45.213 1.00 66.74  ? 532 ASP A CG  1 
ATOM   2477  O OD1 . ASP A 1 330 ? -59.063 -24.809 44.237 1.00 69.24  ? 532 ASP A OD1 1 
ATOM   2478  O OD2 . ASP A 1 330 ? -59.197 -26.217 45.910 1.00 69.88  ? 532 ASP A OD2 1 
ATOM   2479  N N   . ARG A 1 331 ? -56.147 -24.246 42.365 1.00 60.84  ? 533 ARG A N   1 
ATOM   2480  C CA  . ARG A 1 331 ? -55.439 -24.748 41.196 1.00 57.22  ? 533 ARG A CA  1 
ATOM   2481  C C   . ARG A 1 331 ? -54.388 -23.798 40.636 1.00 55.87  ? 533 ARG A C   1 
ATOM   2482  O O   . ARG A 1 331 ? -53.726 -24.114 39.651 1.00 55.09  ? 533 ARG A O   1 
ATOM   2483  C CB  . ARG A 1 331 ? -56.422 -25.165 40.100 1.00 59.24  ? 533 ARG A CB  1 
ATOM   2484  C CG  . ARG A 1 331 ? -57.083 -24.022 39.357 1.00 57.07  ? 533 ARG A CG  1 
ATOM   2485  C CD  . ARG A 1 331 ? -57.964 -24.559 38.245 1.00 57.22  ? 533 ARG A CD  1 
ATOM   2486  N NE  . ARG A 1 331 ? -58.574 -23.493 37.461 1.00 57.73  ? 533 ARG A NE  1 
ATOM   2487  C CZ  . ARG A 1 331 ? -59.648 -22.809 37.839 1.00 57.85  ? 533 ARG A CZ  1 
ATOM   2488  N NH1 . ARG A 1 331 ? -60.231 -23.076 38.998 1.00 58.35  ? 533 ARG A NH1 1 
ATOM   2489  N NH2 . ARG A 1 331 ? -60.135 -21.852 37.062 1.00 56.14  ? 533 ARG A NH2 1 
ATOM   2490  N N   . PHE A 1 332 ? -54.236 -22.633 41.251 1.00 58.18  ? 534 PHE A N   1 
ATOM   2491  C CA  . PHE A 1 332 ? -53.263 -21.666 40.768 1.00 55.70  ? 534 PHE A CA  1 
ATOM   2492  C C   . PHE A 1 332 ? -52.095 -21.450 41.721 1.00 54.72  ? 534 PHE A C   1 
ATOM   2493  O O   . PHE A 1 332 ? -52.269 -21.418 42.933 1.00 55.72  ? 534 PHE A O   1 
ATOM   2494  C CB  . PHE A 1 332 ? -53.943 -20.328 40.481 1.00 57.17  ? 534 PHE A CB  1 
ATOM   2495  C CG  . PHE A 1 332 ? -55.050 -20.416 39.477 1.00 57.39  ? 534 PHE A CG  1 
ATOM   2496  C CD1 . PHE A 1 332 ? -54.773 -20.621 38.141 1.00 57.85  ? 534 PHE A CD1 1 
ATOM   2497  C CD2 . PHE A 1 332 ? -56.368 -20.286 39.869 1.00 58.02  ? 534 PHE A CD2 1 
ATOM   2498  C CE1 . PHE A 1 332 ? -55.790 -20.700 37.213 1.00 58.03  ? 534 PHE A CE1 1 
ATOM   2499  C CE2 . PHE A 1 332 ? -57.390 -20.362 38.947 1.00 57.85  ? 534 PHE A CE2 1 
ATOM   2500  C CZ  . PHE A 1 332 ? -57.101 -20.568 37.617 1.00 57.76  ? 534 PHE A CZ  1 
ATOM   2501  N N   . PHE A 1 333 ? -50.901 -21.314 41.155 1.00 50.85  ? 535 PHE A N   1 
ATOM   2502  C CA  . PHE A 1 333 ? -49.693 -21.058 41.923 1.00 48.97  ? 535 PHE A CA  1 
ATOM   2503  C C   . PHE A 1 333 ? -48.769 -20.153 41.122 1.00 47.99  ? 535 PHE A C   1 
ATOM   2504  O O   . PHE A 1 333 ? -48.727 -20.238 39.890 1.00 47.50  ? 535 PHE A O   1 
ATOM   2505  C CB  . PHE A 1 333 ? -48.966 -22.360 42.304 1.00 49.61  ? 535 PHE A CB  1 
ATOM   2506  C CG  . PHE A 1 333 ? -48.458 -23.153 41.131 1.00 49.86  ? 535 PHE A CG  1 
ATOM   2507  C CD1 . PHE A 1 333 ? -47.159 -22.998 40.684 1.00 48.90  ? 535 PHE A CD1 1 
ATOM   2508  C CD2 . PHE A 1 333 ? -49.280 -24.050 40.478 1.00 50.11  ? 535 PHE A CD2 1 
ATOM   2509  C CE1 . PHE A 1 333 ? -46.689 -23.727 39.613 1.00 47.77  ? 535 PHE A CE1 1 
ATOM   2510  C CE2 . PHE A 1 333 ? -48.815 -24.778 39.403 1.00 49.04  ? 535 PHE A CE2 1 
ATOM   2511  C CZ  . PHE A 1 333 ? -47.519 -24.616 38.971 1.00 47.93  ? 535 PHE A CZ  1 
ATOM   2512  N N   . PRO A 1 334 ? -48.028 -19.273 41.794 1.00 46.85  ? 536 PRO A N   1 
ATOM   2513  C CA  . PRO A 1 334 ? -47.115 -18.379 41.074 1.00 46.45  ? 536 PRO A CA  1 
ATOM   2514  C C   . PRO A 1 334 ? -45.966 -19.154 40.450 1.00 46.22  ? 536 PRO A C   1 
ATOM   2515  O O   . PRO A 1 334 ? -45.548 -20.199 40.952 1.00 46.01  ? 536 PRO A O   1 
ATOM   2516  C CB  . PRO A 1 334 ? -46.623 -17.425 42.167 1.00 45.72  ? 536 PRO A CB  1 
ATOM   2517  C CG  . PRO A 1 334 ? -46.752 -18.205 43.421 1.00 45.79  ? 536 PRO A CG  1 
ATOM   2518  C CD  . PRO A 1 334 ? -47.973 -19.059 43.249 1.00 45.71  ? 536 PRO A CD  1 
ATOM   2519  N N   . LEU A 1 335 ? -45.460 -18.628 39.333 1.00 43.11  ? 537 LEU A N   1 
ATOM   2520  C CA  . LEU A 1 335 ? -44.481 -19.376 38.551 1.00 43.51  ? 537 LEU A CA  1 
ATOM   2521  C C   . LEU A 1 335 ? -43.207 -19.626 39.346 1.00 44.47  ? 537 LEU A C   1 
ATOM   2522  O O   . LEU A 1 335 ? -42.848 -20.779 39.609 1.00 44.76  ? 537 LEU A O   1 
ATOM   2523  C CB  . LEU A 1 335 ? -44.170 -18.622 37.257 1.00 41.08  ? 537 LEU A CB  1 
ATOM   2524  C CG  . LEU A 1 335 ? -43.369 -19.310 36.148 1.00 40.98  ? 537 LEU A CG  1 
ATOM   2525  C CD1 . LEU A 1 335 ? -43.792 -18.763 34.800 1.00 41.04  ? 537 LEU A CD1 1 
ATOM   2526  C CD2 . LEU A 1 335 ? -41.876 -19.139 36.329 1.00 41.89  ? 537 LEU A CD2 1 
ATOM   2527  N N   . SER A 1 336 ? -42.506 -18.560 39.733 1.00 39.62  ? 538 SER A N   1 
ATOM   2528  C CA  . SER A 1 336 ? -41.312 -18.674 40.560 1.00 41.04  ? 538 SER A CA  1 
ATOM   2529  C C   . SER A 1 336 ? -41.560 -18.344 42.028 1.00 41.27  ? 538 SER A C   1 
ATOM   2530  O O   . SER A 1 336 ? -40.609 -18.338 42.814 1.00 41.65  ? 538 SER A O   1 
ATOM   2531  C CB  . SER A 1 336 ? -40.192 -17.786 40.006 1.00 37.86  ? 538 SER A CB  1 
ATOM   2532  O OG  . SER A 1 336 ? -40.554 -16.419 40.046 1.00 40.79  ? 538 SER A OG  1 
ATOM   2533  N N   . GLY A 1 337 ? -42.801 -18.058 42.422 1.00 43.80  ? 539 GLY A N   1 
ATOM   2534  C CA  . GLY A 1 337 ? -43.015 -17.346 43.672 1.00 44.94  ? 539 GLY A CA  1 
ATOM   2535  C C   . GLY A 1 337 ? -43.182 -18.244 44.884 1.00 45.53  ? 539 GLY A C   1 
ATOM   2536  O O   . GLY A 1 337 ? -43.728 -17.820 45.905 1.00 47.89  ? 539 GLY A O   1 
ATOM   2537  N N   . SER A 1 338 ? -42.702 -19.480 44.806 1.00 45.71  ? 540 SER A N   1 
ATOM   2538  C CA  . SER A 1 338 ? -42.829 -20.407 45.920 1.00 45.74  ? 540 SER A CA  1 
ATOM   2539  C C   . SER A 1 338 ? -41.653 -21.371 45.964 1.00 44.51  ? 540 SER A C   1 
ATOM   2540  O O   . SER A 1 338 ? -40.913 -21.534 44.990 1.00 44.49  ? 540 SER A O   1 
ATOM   2541  C CB  . SER A 1 338 ? -44.141 -21.202 45.843 1.00 52.08  ? 540 SER A CB  1 
ATOM   2542  O OG  . SER A 1 338 ? -45.263 -20.352 45.998 1.00 53.63  ? 540 SER A OG  1 
ATOM   2543  N N   . LEU A 1 339 ? -41.488 -22.005 47.122 1.00 46.76  ? 541 LEU A N   1 
ATOM   2544  C CA  . LEU A 1 339 ? -40.480 -23.043 47.274 1.00 45.57  ? 541 LEU A CA  1 
ATOM   2545  C C   . LEU A 1 339 ? -41.059 -24.391 46.874 1.00 45.35  ? 541 LEU A C   1 
ATOM   2546  O O   . LEU A 1 339 ? -42.106 -24.809 47.375 1.00 45.84  ? 541 LEU A O   1 
ATOM   2547  C CB  . LEU A 1 339 ? -39.983 -23.101 48.716 1.00 40.75  ? 541 LEU A CB  1 
ATOM   2548  C CG  . LEU A 1 339 ? -39.284 -21.864 49.272 1.00 39.83  ? 541 LEU A CG  1 
ATOM   2549  C CD1 . LEU A 1 339 ? -38.926 -22.081 50.730 1.00 39.36  ? 541 LEU A CD1 1 
ATOM   2550  C CD2 . LEU A 1 339 ? -38.055 -21.520 48.454 1.00 39.21  ? 541 LEU A CD2 1 
ATOM   2551  N N   . ILE A 1 340 ? -40.372 -25.078 45.968 1.00 46.86  ? 542 ILE A N   1 
ATOM   2552  C CA  . ILE A 1 340 ? -40.847 -26.344 45.428 1.00 47.25  ? 542 ILE A CA  1 
ATOM   2553  C C   . ILE A 1 340 ? -39.925 -27.448 45.919 1.00 46.71  ? 542 ILE A C   1 
ATOM   2554  O O   . ILE A 1 340 ? -38.751 -27.497 45.534 1.00 45.71  ? 542 ILE A O   1 
ATOM   2555  C CB  . ILE A 1 340 ? -40.904 -26.329 43.895 1.00 44.00  ? 542 ILE A CB  1 
ATOM   2556  C CG1 . ILE A 1 340 ? -41.859 -25.239 43.417 1.00 46.84  ? 542 ILE A CG1 1 
ATOM   2557  C CG2 . ILE A 1 340 ? -41.383 -27.666 43.381 1.00 45.28  ? 542 ILE A CG2 1 
ATOM   2558  C CD1 . ILE A 1 340 ? -41.808 -25.000 41.932 1.00 48.68  ? 542 ILE A CD1 1 
ATOM   2559  N N   . PHE A 1 341 ? -40.452 -28.333 46.755 1.00 50.85  ? 543 PHE A N   1 
ATOM   2560  C CA  . PHE A 1 341 ? -39.702 -29.471 47.262 1.00 50.72  ? 543 PHE A CA  1 
ATOM   2561  C C   . PHE A 1 341 ? -40.070 -30.726 46.485 1.00 50.13  ? 543 PHE A C   1 
ATOM   2562  O O   . PHE A 1 341 ? -41.218 -30.906 46.073 1.00 48.96  ? 543 PHE A O   1 
ATOM   2563  C CB  . PHE A 1 341 ? -39.975 -29.698 48.750 1.00 43.72  ? 543 PHE A CB  1 
ATOM   2564  C CG  . PHE A 1 341 ? -39.565 -28.557 49.625 1.00 44.21  ? 543 PHE A CG  1 
ATOM   2565  C CD1 . PHE A 1 341 ? -38.249 -28.408 50.017 1.00 44.29  ? 543 PHE A CD1 1 
ATOM   2566  C CD2 . PHE A 1 341 ? -40.500 -27.643 50.073 1.00 44.06  ? 543 PHE A CD2 1 
ATOM   2567  C CE1 . PHE A 1 341 ? -37.870 -27.360 50.829 1.00 43.84  ? 543 PHE A CE1 1 
ATOM   2568  C CE2 . PHE A 1 341 ? -40.126 -26.596 50.887 1.00 43.74  ? 543 PHE A CE2 1 
ATOM   2569  C CZ  . PHE A 1 341 ? -38.809 -26.454 51.264 1.00 43.60  ? 543 PHE A CZ  1 
ATOM   2570  N N   . GLY A 1 342 ? -39.083 -31.590 46.278 1.00 55.81  ? 544 GLY A N   1 
ATOM   2571  C CA  . GLY A 1 342 ? -39.327 -32.869 45.645 1.00 55.86  ? 544 GLY A CA  1 
ATOM   2572  C C   . GLY A 1 342 ? -39.704 -33.952 46.641 1.00 56.06  ? 544 GLY A C   1 
ATOM   2573  O O   . GLY A 1 342 ? -39.253 -33.960 47.782 1.00 56.60  ? 544 GLY A O   1 
ATOM   2574  N N   . LYS A 1 343 ? -40.549 -34.871 46.189 1.00 58.85  ? 545 LYS A N   1 
ATOM   2575  C CA  . LYS A 1 343 ? -40.855 -36.060 46.966 1.00 58.42  ? 545 LYS A CA  1 
ATOM   2576  C C   . LYS A 1 343 ? -39.692 -37.044 46.893 1.00 59.02  ? 545 LYS A C   1 
ATOM   2577  O O   . LYS A 1 343 ? -38.832 -36.962 46.013 1.00 58.15  ? 545 LYS A O   1 
ATOM   2578  C CB  . LYS A 1 343 ? -42.145 -36.711 46.471 1.00 55.49  ? 545 LYS A CB  1 
ATOM   2579  C CG  . LYS A 1 343 ? -43.377 -35.864 46.724 1.00 55.99  ? 545 LYS A CG  1 
ATOM   2580  C CD  . LYS A 1 343 ? -44.629 -36.496 46.148 1.00 57.04  ? 545 LYS A CD  1 
ATOM   2581  C CE  . LYS A 1 343 ? -45.848 -35.638 46.435 1.00 58.95  ? 545 LYS A CE  1 
ATOM   2582  N NZ  . LYS A 1 343 ? -47.085 -36.195 45.826 1.00 60.18  ? 545 LYS A NZ  1 
ATOM   2583  N N   . GLN A 1 344 ? -39.667 -37.970 47.848 1.00 63.85  ? 546 GLN A N   1 
ATOM   2584  C CA  . GLN A 1 344 ? -38.564 -38.918 47.948 1.00 65.03  ? 546 GLN A CA  1 
ATOM   2585  C C   . GLN A 1 344 ? -38.391 -39.693 46.647 1.00 65.06  ? 546 GLN A C   1 
ATOM   2586  O O   . GLN A 1 344 ? -39.338 -40.296 46.135 1.00 64.50  ? 546 GLN A O   1 
ATOM   2587  C CB  . GLN A 1 344 ? -38.809 -39.880 49.109 1.00 66.91  ? 546 GLN A CB  1 
ATOM   2588  C CG  . GLN A 1 344 ? -37.675 -40.855 49.358 1.00 71.31  ? 546 GLN A CG  1 
ATOM   2589  C CD  . GLN A 1 344 ? -36.401 -40.163 49.801 1.00 73.41  ? 546 GLN A CD  1 
ATOM   2590  O OE1 . GLN A 1 344 ? -35.481 -39.966 49.011 1.00 75.77  ? 546 GLN A OE1 1 
ATOM   2591  N NE2 . GLN A 1 344 ? -36.345 -39.788 51.072 1.00 73.32  ? 546 GLN A NE2 1 
ATOM   2592  N N   . GLY A 1 345 ? -37.173 -39.670 46.112 1.00 63.01  ? 547 GLY A N   1 
ATOM   2593  C CA  . GLY A 1 345 ? -36.873 -40.362 44.877 1.00 63.16  ? 547 GLY A CA  1 
ATOM   2594  C C   . GLY A 1 345 ? -37.142 -39.584 43.609 1.00 63.53  ? 547 GLY A C   1 
ATOM   2595  O O   . GLY A 1 345 ? -37.081 -40.168 42.521 1.00 64.12  ? 547 GLY A O   1 
ATOM   2596  N N   . THR A 1 346 ? -37.432 -38.290 43.705 1.00 58.99  ? 548 THR A N   1 
ATOM   2597  C CA  . THR A 1 346 ? -37.740 -37.490 42.529 1.00 58.65  ? 548 THR A CA  1 
ATOM   2598  C C   . THR A 1 346 ? -36.484 -37.248 41.701 1.00 59.51  ? 548 THR A C   1 
ATOM   2599  O O   . THR A 1 346 ? -35.402 -37.001 42.242 1.00 57.98  ? 548 THR A O   1 
ATOM   2600  C CB  . THR A 1 346 ? -38.368 -36.159 42.943 1.00 57.02  ? 548 THR A CB  1 
ATOM   2601  O OG1 . THR A 1 346 ? -39.570 -36.410 43.679 1.00 57.72  ? 548 THR A OG1 1 
ATOM   2602  C CG2 . THR A 1 346 ? -38.706 -35.313 41.727 1.00 55.72  ? 548 THR A CG2 1 
ATOM   2603  N N   . GLY A 1 347 ? -36.631 -37.330 40.385 1.00 55.10  ? 549 GLY A N   1 
ATOM   2604  C CA  . GLY A 1 347 ? -35.508 -37.140 39.489 1.00 56.54  ? 549 GLY A CA  1 
ATOM   2605  C C   . GLY A 1 347 ? -35.010 -35.707 39.478 1.00 58.09  ? 549 GLY A C   1 
ATOM   2606  O O   . GLY A 1 347 ? -35.620 -34.781 40.011 1.00 56.80  ? 549 GLY A O   1 
ATOM   2607  N N   . ARG A 1 348 ? -33.846 -35.532 38.859 1.00 49.28  ? 550 ARG A N   1 
ATOM   2608  C CA  . ARG A 1 348 ? -33.184 -34.236 38.844 1.00 52.17  ? 550 ARG A CA  1 
ATOM   2609  C C   . ARG A 1 348 ? -33.636 -33.338 37.697 1.00 52.72  ? 550 ARG A C   1 
ATOM   2610  O O   . ARG A 1 348 ? -33.456 -32.117 37.775 1.00 52.27  ? 550 ARG A O   1 
ATOM   2611  C CB  . ARG A 1 348 ? -31.668 -34.448 38.794 1.00 41.04  ? 550 ARG A CB  1 
ATOM   2612  C CG  . ARG A 1 348 ? -30.834 -33.189 38.876 1.00 49.39  ? 550 ARG A CG  1 
ATOM   2613  C CD  . ARG A 1 348 ? -29.358 -33.513 38.860 1.00 54.38  ? 550 ARG A CD  1 
ATOM   2614  N NE  . ARG A 1 348 ? -28.551 -32.301 38.910 1.00 59.28  ? 550 ARG A NE  1 
ATOM   2615  C CZ  . ARG A 1 348 ? -28.205 -31.596 37.839 1.00 62.64  ? 550 ARG A CZ  1 
ATOM   2616  N NH1 . ARG A 1 348 ? -28.594 -31.987 36.633 1.00 62.78  ? 550 ARG A NH1 1 
ATOM   2617  N NH2 . ARG A 1 348 ? -27.470 -30.502 37.973 1.00 64.35  ? 550 ARG A NH2 1 
ATOM   2618  N N   . ASP A 1 349 ? -34.263 -33.893 36.661 1.00 52.02  ? 551 ASP A N   1 
ATOM   2619  C CA  . ASP A 1 349 ? -34.608 -33.130 35.467 1.00 53.40  ? 551 ASP A CA  1 
ATOM   2620  C C   . ASP A 1 349 ? -35.994 -33.508 34.970 1.00 52.15  ? 551 ASP A C   1 
ATOM   2621  O O   . ASP A 1 349 ? -36.301 -34.696 34.836 1.00 52.37  ? 551 ASP A O   1 
ATOM   2622  C CB  . ASP A 1 349 ? -33.590 -33.366 34.344 1.00 51.94  ? 551 ASP A CB  1 
ATOM   2623  C CG  . ASP A 1 349 ? -32.258 -32.691 34.602 1.00 57.14  ? 551 ASP A CG  1 
ATOM   2624  O OD1 . ASP A 1 349 ? -32.205 -31.761 35.431 1.00 59.96  ? 551 ASP A OD1 1 
ATOM   2625  O OD2 . ASP A 1 349 ? -31.259 -33.094 33.972 1.00 58.95  ? 551 ASP A OD2 1 
ATOM   2626  N N   . ASN A 1 350 ? -36.817 -32.495 34.687 1.00 52.82  ? 552 ASN A N   1 
ATOM   2627  C CA  . ASN A 1 350 ? -38.074 -32.653 33.951 1.00 51.03  ? 552 ASN A CA  1 
ATOM   2628  C C   . ASN A 1 350 ? -38.994 -33.685 34.606 1.00 49.02  ? 552 ASN A C   1 
ATOM   2629  O O   . ASN A 1 350 ? -39.425 -34.658 33.986 1.00 48.37  ? 552 ASN A O   1 
ATOM   2630  C CB  . ASN A 1 350 ? -37.803 -33.013 32.488 1.00 51.31  ? 552 ASN A CB  1 
ATOM   2631  C CG  . ASN A 1 350 ? -37.175 -31.874 31.715 1.00 52.62  ? 552 ASN A CG  1 
ATOM   2632  O OD1 . ASN A 1 350 ? -37.306 -30.710 32.087 1.00 51.82  ? 552 ASN A OD1 1 
ATOM   2633  N ND2 . ASN A 1 350 ? -36.488 -32.204 30.630 1.00 54.28  ? 552 ASN A ND2 1 
ATOM   2634  N N   . VAL A 1 351 ? -39.295 -33.455 35.876 1.00 54.30  ? 553 VAL A N   1 
ATOM   2635  C CA  . VAL A 1 351 ? -40.124 -34.366 36.655 1.00 53.27  ? 553 VAL A CA  1 
ATOM   2636  C C   . VAL A 1 351 ? -41.545 -33.828 36.699 1.00 53.69  ? 553 VAL A C   1 
ATOM   2637  O O   . VAL A 1 351 ? -41.778 -32.614 36.673 1.00 53.02  ? 553 VAL A O   1 
ATOM   2638  C CB  . VAL A 1 351 ? -39.567 -34.572 38.077 1.00 52.89  ? 553 VAL A CB  1 
ATOM   2639  C CG1 . VAL A 1 351 ? -38.185 -35.182 38.007 1.00 54.98  ? 553 VAL A CG1 1 
ATOM   2640  C CG2 . VAL A 1 351 ? -39.551 -33.264 38.840 1.00 51.52  ? 553 VAL A CG2 1 
ATOM   2641  N N   . ASP A 1 352 ? -42.508 -34.742 36.754 1.00 56.32  ? 554 ASP A N   1 
ATOM   2642  C CA  . ASP A 1 352 ? -43.905 -34.359 36.652 1.00 58.57  ? 554 ASP A CA  1 
ATOM   2643  C C   . ASP A 1 352 ? -44.367 -33.649 37.923 1.00 57.34  ? 554 ASP A C   1 
ATOM   2644  O O   . ASP A 1 352 ? -43.623 -33.494 38.895 1.00 57.76  ? 554 ASP A O   1 
ATOM   2645  C CB  . ASP A 1 352 ? -44.771 -35.587 36.380 1.00 56.81  ? 554 ASP A CB  1 
ATOM   2646  C CG  . ASP A 1 352 ? -44.529 -36.172 35.005 1.00 62.62  ? 554 ASP A CG  1 
ATOM   2647  O OD1 . ASP A 1 352 ? -43.946 -35.467 34.156 1.00 65.17  ? 554 ASP A OD1 1 
ATOM   2648  O OD2 . ASP A 1 352 ? -44.911 -37.338 34.773 1.00 66.57  ? 554 ASP A OD2 1 
ATOM   2649  N N   . ALA A 1 353 ? -45.632 -33.224 37.909 1.00 59.94  ? 555 ALA A N   1 
ATOM   2650  C CA  . ALA A 1 353 ? -46.157 -32.426 39.011 1.00 58.96  ? 555 ALA A CA  1 
ATOM   2651  C C   . ALA A 1 353 ? -46.362 -33.258 40.269 1.00 59.03  ? 555 ALA A C   1 
ATOM   2652  O O   . ALA A 1 353 ? -46.184 -32.748 41.380 1.00 58.53  ? 555 ALA A O   1 
ATOM   2653  C CB  . ALA A 1 353 ? -47.466 -31.758 38.599 1.00 56.74  ? 555 ALA A CB  1 
ATOM   2654  N N   . ASP A 1 354 ? -46.737 -34.529 40.123 1.00 60.74  ? 556 ASP A N   1 
ATOM   2655  C CA  . ASP A 1 354 ? -46.930 -35.378 41.291 1.00 61.29  ? 556 ASP A CA  1 
ATOM   2656  C C   . ASP A 1 354 ? -45.626 -35.743 41.989 1.00 59.32  ? 556 ASP A C   1 
ATOM   2657  O O   . ASP A 1 354 ? -45.671 -36.222 43.126 1.00 58.45  ? 556 ASP A O   1 
ATOM   2658  C CB  . ASP A 1 354 ? -47.683 -36.651 40.899 1.00 60.13  ? 556 ASP A CB  1 
ATOM   2659  C CG  . ASP A 1 354 ? -46.996 -37.418 39.789 1.00 65.40  ? 556 ASP A CG  1 
ATOM   2660  O OD1 . ASP A 1 354 ? -46.050 -36.873 39.188 1.00 68.87  ? 556 ASP A OD1 1 
ATOM   2661  O OD2 . ASP A 1 354 ? -47.394 -38.572 39.525 1.00 68.42  ? 556 ASP A OD2 1 
ATOM   2662  N N   . LYS A 1 355 ? -44.475 -35.528 41.351 1.00 59.82  ? 557 LYS A N   1 
ATOM   2663  C CA  . LYS A 1 355 ? -43.190 -35.845 41.960 1.00 57.72  ? 557 LYS A CA  1 
ATOM   2664  C C   . LYS A 1 355 ? -42.632 -34.722 42.823 1.00 55.23  ? 557 LYS A C   1 
ATOM   2665  O O   . LYS A 1 355 ? -41.561 -34.895 43.413 1.00 53.60  ? 557 LYS A O   1 
ATOM   2666  C CB  . LYS A 1 355 ? -42.158 -36.201 40.884 1.00 54.56  ? 557 LYS A CB  1 
ATOM   2667  C CG  . LYS A 1 355 ? -42.052 -37.685 40.563 1.00 57.59  ? 557 LYS A CG  1 
ATOM   2668  C CD  . LYS A 1 355 ? -43.292 -38.202 39.869 1.00 61.28  ? 557 LYS A CD  1 
ATOM   2669  C CE  . LYS A 1 355 ? -43.177 -39.682 39.555 1.00 65.67  ? 557 LYS A CE  1 
ATOM   2670  N NZ  . LYS A 1 355 ? -44.393 -40.192 38.864 1.00 62.81  ? 557 LYS A NZ  1 
ATOM   2671  N N   . VAL A 1 356 ? -43.319 -33.586 42.918 1.00 54.31  ? 558 VAL A N   1 
ATOM   2672  C CA  . VAL A 1 356 ? -42.829 -32.443 43.676 1.00 53.50  ? 558 VAL A CA  1 
ATOM   2673  C C   . VAL A 1 356 ? -43.912 -31.978 44.639 1.00 53.35  ? 558 VAL A C   1 
ATOM   2674  O O   . VAL A 1 356 ? -45.086 -32.337 44.519 1.00 53.35  ? 558 VAL A O   1 
ATOM   2675  C CB  . VAL A 1 356 ? -42.387 -31.282 42.761 1.00 51.17  ? 558 VAL A CB  1 
ATOM   2676  C CG1 . VAL A 1 356 ? -41.187 -31.687 41.924 1.00 54.72  ? 558 VAL A CG1 1 
ATOM   2677  C CG2 . VAL A 1 356 ? -43.535 -30.847 41.870 1.00 51.19  ? 558 VAL A CG2 1 
ATOM   2678  N N   . MET A 1 357 ? -43.497 -31.156 45.596 1.00 52.30  ? 559 MET A N   1 
ATOM   2679  C CA  . MET A 1 357 ? -44.400 -30.572 46.578 1.00 52.57  ? 559 MET A CA  1 
ATOM   2680  C C   . MET A 1 357 ? -44.266 -29.057 46.510 1.00 52.41  ? 559 MET A C   1 
ATOM   2681  O O   . MET A 1 357 ? -43.215 -28.520 46.828 1.00 51.86  ? 559 MET A O   1 
ATOM   2682  C CB  . MET A 1 357 ? -44.042 -31.033 47.987 1.00 53.55  ? 559 MET A CB  1 
ATOM   2683  C CG  . MET A 1 357 ? -43.929 -32.534 48.160 1.00 57.78  ? 559 MET A CG  1 
ATOM   2684  S SD  . MET A 1 357 ? -43.520 -32.972 49.857 1.00 62.23  ? 559 MET A SD  1 
ATOM   2685  C CE  . MET A 1 357 ? -42.171 -31.848 50.190 1.00 61.93  ? 559 MET A CE  1 
ATOM   2686  N N   . ILE A 1 358 ? -45.326 -28.364 46.113 1.00 48.62  ? 560 ILE A N   1 
ATOM   2687  C CA  . ILE A 1 358 ? -45.271 -26.913 46.025 1.00 48.57  ? 560 ILE A CA  1 
ATOM   2688  C C   . ILE A 1 358 ? -45.923 -26.283 47.246 1.00 50.62  ? 560 ILE A C   1 
ATOM   2689  O O   . ILE A 1 358 ? -47.091 -26.522 47.530 1.00 50.61  ? 560 ILE A O   1 
ATOM   2690  C CB  . ILE A 1 358 ? -45.994 -26.405 44.770 1.00 50.35  ? 560 ILE A CB  1 
ATOM   2691  C CG1 . ILE A 1 358 ? -45.401 -27.043 43.519 1.00 48.88  ? 560 ILE A CG1 1 
ATOM   2692  C CG2 . ILE A 1 358 ? -45.903 -24.893 44.678 1.00 49.34  ? 560 ILE A CG2 1 
ATOM   2693  C CD1 . ILE A 1 358 ? -46.186 -26.746 42.264 1.00 47.04  ? 560 ILE A CD1 1 
ATOM   2694  N N   . THR A 1 359 ? -45.151 -25.483 47.971 1.00 48.31  ? 561 THR A N   1 
ATOM   2695  C CA  . THR A 1 359 ? -45.637 -24.809 49.165 1.00 51.36  ? 561 THR A CA  1 
ATOM   2696  C C   . THR A 1 359 ? -46.557 -23.648 48.814 1.00 54.71  ? 561 THR A C   1 
ATOM   2697  O O   . THR A 1 359 ? -46.491 -23.108 47.714 1.00 54.18  ? 561 THR A O   1 
ATOM   2698  C CB  . THR A 1 359 ? -44.479 -24.284 50.023 1.00 50.75  ? 561 THR A CB  1 
ATOM   2699  O OG1 . THR A 1 359 ? -43.989 -23.058 49.468 1.00 52.27  ? 561 THR A OG1 1 
ATOM   2700  C CG2 . THR A 1 359 ? -43.360 -25.297 50.067 1.00 50.19  ? 561 THR A CG2 1 
ATOM   2701  N N   . ASN A 1 360 ? -47.426 -23.273 49.742 1.00 50.83  ? 562 ASN A N   1 
ATOM   2702  C CA  . ASN A 1 360 ? -48.331 -22.158 49.500 1.00 55.02  ? 562 ASN A CA  1 
ATOM   2703  C C   . ASN A 1 360 ? -48.273 -21.142 50.641 1.00 56.64  ? 562 ASN A C   1 
ATOM   2704  O O   . ASN A 1 360 ? -47.994 -21.487 51.783 1.00 57.90  ? 562 ASN A O   1 
ATOM   2705  C CB  . ASN A 1 360 ? -49.757 -22.639 49.197 1.00 55.49  ? 562 ASN A CB  1 
ATOM   2706  C CG  . ASN A 1 360 ? -50.541 -22.985 50.440 1.00 59.67  ? 562 ASN A CG  1 
ATOM   2707  O OD1 . ASN A 1 360 ? -49.997 -23.047 51.539 1.00 63.99  ? 562 ASN A OD1 1 
ATOM   2708  N ND2 . ASN A 1 360 ? -51.835 -23.210 50.271 1.00 61.79  ? 562 ASN A ND2 1 
ATOM   2709  N N   . GLU A 1 361 ? -48.524 -19.882 50.311 1.00 53.45  ? 563 GLU A N   1 
ATOM   2710  C CA  . GLU A 1 361 ? -48.460 -18.790 51.275 1.00 55.46  ? 563 GLU A CA  1 
ATOM   2711  C C   . GLU A 1 361 ? -49.823 -18.165 51.559 1.00 54.36  ? 563 GLU A C   1 
ATOM   2712  O O   . GLU A 1 361 ? -49.934 -16.957 51.715 1.00 56.00  ? 563 GLU A O   1 
ATOM   2713  C CB  . GLU A 1 361 ? -47.467 -17.720 50.815 1.00 43.23  ? 563 GLU A CB  1 
ATOM   2714  C CG  . GLU A 1 361 ? -46.040 -18.220 50.660 1.00 48.99  ? 563 GLU A CG  1 
ATOM   2715  C CD  . GLU A 1 361 ? -45.320 -18.376 51.984 1.00 52.05  ? 563 GLU A CD  1 
ATOM   2716  O OE1 . GLU A 1 361 ? -45.463 -17.490 52.847 1.00 52.22  ? 563 GLU A OE1 1 
ATOM   2717  O OE2 . GLU A 1 361 ? -44.597 -19.379 52.158 1.00 54.52  ? 563 GLU A OE2 1 
ATOM   2718  N N   . GLU A 1 362 ? -50.857 -18.992 51.613 1.00 57.00  ? 564 GLU A N   1 
ATOM   2719  C CA  . GLU A 1 362 ? -52.214 -18.515 51.851 1.00 55.57  ? 564 GLU A CA  1 
ATOM   2720  C C   . GLU A 1 362 ? -52.402 -17.793 53.188 1.00 53.48  ? 564 GLU A C   1 
ATOM   2721  O O   . GLU A 1 362 ? -53.173 -16.850 53.274 1.00 53.11  ? 564 GLU A O   1 
ATOM   2722  C CB  . GLU A 1 362 ? -53.234 -19.650 51.692 1.00 58.91  ? 564 GLU A CB  1 
ATOM   2723  C CG  . GLU A 1 362 ? -53.073 -20.807 52.664 1.00 63.07  ? 564 GLU A CG  1 
ATOM   2724  C CD  . GLU A 1 362 ? -53.856 -20.621 53.949 1.00 65.35  ? 564 GLU A CD  1 
ATOM   2725  O OE1 . GLU A 1 362 ? -54.638 -19.653 54.043 1.00 66.09  ? 564 GLU A OE1 1 
ATOM   2726  O OE2 . GLU A 1 362 ? -53.685 -21.442 54.873 1.00 66.51  ? 564 GLU A OE2 1 
ATOM   2727  N N   . GLU A 1 363 ? -51.687 -18.221 54.220 1.00 53.91  ? 565 GLU A N   1 
ATOM   2728  C CA  . GLU A 1 363 ? -51.829 -17.634 55.552 1.00 52.20  ? 565 GLU A CA  1 
ATOM   2729  C C   . GLU A 1 363 ? -51.526 -16.138 55.627 1.00 48.44  ? 565 GLU A C   1 
ATOM   2730  O O   . GLU A 1 363 ? -52.150 -15.417 56.395 1.00 48.30  ? 565 GLU A O   1 
ATOM   2731  C CB  . GLU A 1 363 ? -50.945 -18.367 56.562 1.00 52.45  ? 565 GLU A CB  1 
ATOM   2732  C CG  . GLU A 1 363 ? -51.051 -19.879 56.524 1.00 60.27  ? 565 GLU A CG  1 
ATOM   2733  C CD  . GLU A 1 363 ? -50.337 -20.472 55.332 1.00 64.48  ? 565 GLU A CD  1 
ATOM   2734  O OE1 . GLU A 1 363 ? -50.114 -19.736 54.352 1.00 64.65  ? 565 GLU A OE1 1 
ATOM   2735  O OE2 . GLU A 1 363 ? -49.999 -21.672 55.373 1.00 67.34  ? 565 GLU A OE2 1 
ATOM   2736  N N   . ILE A 1 364 ? -50.563 -15.674 54.844 1.00 49.08  ? 566 ILE A N   1 
ATOM   2737  C CA  . ILE A 1 364 ? -50.162 -14.270 54.883 1.00 44.21  ? 566 ILE A CA  1 
ATOM   2738  C C   . ILE A 1 364 ? -51.014 -13.318 54.052 1.00 42.91  ? 566 ILE A C   1 
ATOM   2739  O O   . ILE A 1 364 ? -50.736 -12.125 54.009 1.00 42.20  ? 566 ILE A O   1 
ATOM   2740  C CB  . ILE A 1 364 ? -48.682 -14.078 54.511 1.00 44.42  ? 566 ILE A CB  1 
ATOM   2741  C CG1 . ILE A 1 364 ? -48.444 -14.438 53.049 1.00 42.79  ? 566 ILE A CG1 1 
ATOM   2742  C CG2 . ILE A 1 364 ? -47.795 -14.905 55.424 1.00 43.98  ? 566 ILE A CG2 1 
ATOM   2743  C CD1 . ILE A 1 364 ? -46.984 -14.447 52.656 1.00 40.85  ? 566 ILE A CD1 1 
ATOM   2744  N N   . LYS A 1 365 ? -52.064 -13.820 53.415 1.00 45.29  ? 567 LYS A N   1 
ATOM   2745  C CA  . LYS A 1 365 ? -52.902 -12.959 52.584 1.00 44.46  ? 567 LYS A CA  1 
ATOM   2746  C C   . LYS A 1 365 ? -53.539 -11.799 53.356 1.00 43.48  ? 567 LYS A C   1 
ATOM   2747  O O   . LYS A 1 365 ? -53.688 -10.714 52.801 1.00 43.36  ? 567 LYS A O   1 
ATOM   2748  C CB  . LYS A 1 365 ? -53.947 -13.759 51.802 1.00 47.45  ? 567 LYS A CB  1 
ATOM   2749  C CG  . LYS A 1 365 ? -55.081 -14.339 52.625 1.00 50.33  ? 567 LYS A CG  1 
ATOM   2750  C CD  . LYS A 1 365 ? -55.912 -15.288 51.779 1.00 55.00  ? 567 LYS A CD  1 
ATOM   2751  C CE  . LYS A 1 365 ? -56.889 -16.080 52.629 1.00 56.49  ? 567 LYS A CE  1 
ATOM   2752  N NZ  . LYS A 1 365 ? -56.199 -16.896 53.661 1.00 58.95  ? 567 LYS A NZ  1 
ATOM   2753  N N   . THR A 1 366 ? -53.940 -12.031 54.605 1.00 43.12  ? 568 THR A N   1 
ATOM   2754  C CA  . THR A 1 366 ? -54.529 -10.993 55.453 1.00 41.49  ? 568 THR A CA  1 
ATOM   2755  C C   . THR A 1 366 ? -53.768 -9.657  55.426 1.00 41.21  ? 568 THR A C   1 
ATOM   2756  O O   . THR A 1 366 ? -54.387 -8.601  55.433 1.00 40.79  ? 568 THR A O   1 
ATOM   2757  C CB  . THR A 1 366 ? -54.675 -11.474 56.905 1.00 39.02  ? 568 THR A CB  1 
ATOM   2758  O OG1 . THR A 1 366 ? -53.439 -12.042 57.346 1.00 41.64  ? 568 THR A OG1 1 
ATOM   2759  C CG2 . THR A 1 366 ? -55.760 -12.520 57.005 1.00 38.17  ? 568 THR A CG2 1 
ATOM   2760  N N   . THR A 1 367 ? -52.437 -9.703  55.411 1.00 39.16  ? 569 THR A N   1 
ATOM   2761  C CA  . THR A 1 367 ? -51.636 -8.491  55.322 1.00 38.93  ? 569 THR A CA  1 
ATOM   2762  C C   . THR A 1 367 ? -50.840 -8.355  54.030 1.00 38.32  ? 569 THR A C   1 
ATOM   2763  O O   . THR A 1 367 ? -50.171 -7.333  53.849 1.00 38.42  ? 569 THR A O   1 
ATOM   2764  C CB  . THR A 1 367 ? -50.667 -8.405  56.509 1.00 38.84  ? 569 THR A CB  1 
ATOM   2765  O OG1 . THR A 1 367 ? -49.805 -9.548  56.505 1.00 40.29  ? 569 THR A OG1 1 
ATOM   2766  C CG2 . THR A 1 367 ? -51.435 -8.361  57.816 1.00 38.89  ? 569 THR A CG2 1 
ATOM   2767  N N   . ASN A 1 368 ? -50.885 -9.338  53.132 1.00 38.80  ? 570 ASN A N   1 
ATOM   2768  C CA  . ASN A 1 368 ? -50.019 -9.263  51.964 1.00 38.76  ? 570 ASN A CA  1 
ATOM   2769  C C   . ASN A 1 368 ? -50.813 -9.366  50.668 1.00 39.72  ? 570 ASN A C   1 
ATOM   2770  O O   . ASN A 1 368 ? -51.856 -10.025 50.621 1.00 41.15  ? 570 ASN A O   1 
ATOM   2771  C CB  . ASN A 1 368 ? -48.955 -10.366 51.982 1.00 37.03  ? 570 ASN A CB  1 
ATOM   2772  C CG  . ASN A 1 368 ? -47.882 -10.115 53.009 1.00 37.74  ? 570 ASN A CG  1 
ATOM   2773  O OD1 . ASN A 1 368 ? -47.680 -8.984  53.436 1.00 38.33  ? 570 ASN A OD1 1 
ATOM   2774  N ND2 . ASN A 1 368 ? -47.170 -11.162 53.395 1.00 38.45  ? 570 ASN A ND2 1 
ATOM   2775  N N   . PRO A 1 369 ? -50.340 -8.725  49.602 1.00 40.63  ? 571 PRO A N   1 
ATOM   2776  C CA  . PRO A 1 369 ? -51.003 -8.862  48.304 1.00 40.73  ? 571 PRO A CA  1 
ATOM   2777  C C   . PRO A 1 369 ? -50.705 -10.209 47.667 1.00 41.08  ? 571 PRO A C   1 
ATOM   2778  O O   . PRO A 1 369 ? -49.722 -10.880 47.983 1.00 41.19  ? 571 PRO A O   1 
ATOM   2779  C CB  . PRO A 1 369 ? -50.405 -7.718  47.482 1.00 37.98  ? 571 PRO A CB  1 
ATOM   2780  C CG  . PRO A 1 369 ? -49.066 -7.504  48.079 1.00 37.93  ? 571 PRO A CG  1 
ATOM   2781  C CD  . PRO A 1 369 ? -49.221 -7.768  49.548 1.00 37.57  ? 571 PRO A CD  1 
ATOM   2782  N N   . VAL A 1 370 ? -51.588 -10.603 46.749 1.00 43.47  ? 572 VAL A N   1 
ATOM   2783  C CA  . VAL A 1 370 ? -51.417 -11.860 46.035 1.00 42.85  ? 572 VAL A CA  1 
ATOM   2784  C C   . VAL A 1 370 ? -50.244 -11.739 45.073 1.00 43.27  ? 572 VAL A C   1 
ATOM   2785  O O   . VAL A 1 370 ? -50.004 -10.674 44.488 1.00 43.06  ? 572 VAL A O   1 
ATOM   2786  C CB  . VAL A 1 370 ? -52.720 -12.231 45.306 1.00 46.61  ? 572 VAL A CB  1 
ATOM   2787  C CG1 . VAL A 1 370 ? -52.549 -13.496 44.490 1.00 46.31  ? 572 VAL A CG1 1 
ATOM   2788  C CG2 . VAL A 1 370 ? -53.848 -12.393 46.304 1.00 46.20  ? 572 VAL A CG2 1 
ATOM   2789  N N   . ALA A 1 371 ? -49.496 -12.833 44.910 1.00 40.29  ? 573 ALA A N   1 
ATOM   2790  C CA  . ALA A 1 371 ? -48.305 -12.798 44.070 1.00 40.36  ? 573 ALA A CA  1 
ATOM   2791  C C   . ALA A 1 371 ? -48.644 -12.602 42.598 1.00 40.96  ? 573 ALA A C   1 
ATOM   2792  O O   . ALA A 1 371 ? -47.873 -11.975 41.865 1.00 40.32  ? 573 ALA A O   1 
ATOM   2793  C CB  . ALA A 1 371 ? -47.494 -14.078 44.258 1.00 41.31  ? 573 ALA A CB  1 
ATOM   2794  N N   . THR A 1 372 ? -49.780 -13.124 42.147 1.00 43.65  ? 574 THR A N   1 
ATOM   2795  C CA  . THR A 1 372 ? -50.172 -13.067 40.747 1.00 44.14  ? 574 THR A CA  1 
ATOM   2796  C C   . THR A 1 372 ? -51.077 -11.884 40.431 1.00 45.03  ? 574 THR A C   1 
ATOM   2797  O O   . THR A 1 372 ? -51.579 -11.785 39.308 1.00 46.23  ? 574 THR A O   1 
ATOM   2798  C CB  . THR A 1 372 ? -50.860 -14.369 40.345 1.00 45.28  ? 574 THR A CB  1 
ATOM   2799  O OG1 . THR A 1 372 ? -52.012 -14.575 41.172 1.00 45.29  ? 574 THR A OG1 1 
ATOM   2800  C CG2 . THR A 1 372 ? -49.909 -15.537 40.515 1.00 44.75  ? 574 THR A CG2 1 
ATOM   2801  N N   . GLU A 1 373 ? -51.308 -10.998 41.392 1.00 42.84  ? 575 GLU A N   1 
ATOM   2802  C CA  . GLU A 1 373 ? -52.194 -9.858  41.222 1.00 44.37  ? 575 GLU A CA  1 
ATOM   2803  C C   . GLU A 1 373 ? -51.399 -8.560  41.263 1.00 42.93  ? 575 GLU A C   1 
ATOM   2804  O O   . GLU A 1 373 ? -50.315 -8.485  41.847 1.00 42.63  ? 575 GLU A O   1 
ATOM   2805  C CB  . GLU A 1 373 ? -53.271 -9.829  42.314 1.00 44.46  ? 575 GLU A CB  1 
ATOM   2806  C CG  . GLU A 1 373 ? -54.242 -10.995 42.301 1.00 51.46  ? 575 GLU A CG  1 
ATOM   2807  C CD  . GLU A 1 373 ? -55.026 -11.093 41.013 1.00 55.81  ? 575 GLU A CD  1 
ATOM   2808  O OE1 . GLU A 1 373 ? -55.400 -10.039 40.459 1.00 58.35  ? 575 GLU A OE1 1 
ATOM   2809  O OE2 . GLU A 1 373 ? -55.280 -12.227 40.561 1.00 58.46  ? 575 GLU A OE2 1 
ATOM   2810  N N   . SER A 1 374 ? -51.953 -7.534  40.625 1.00 39.21  ? 576 SER A N   1 
ATOM   2811  C CA  . SER A 1 374 ? -51.366 -6.207  40.703 1.00 39.11  ? 576 SER A CA  1 
ATOM   2812  C C   . SER A 1 374 ? -51.571 -5.624  42.094 1.00 38.47  ? 576 SER A C   1 
ATOM   2813  O O   . SER A 1 374 ? -52.523 -5.964  42.800 1.00 39.29  ? 576 SER A O   1 
ATOM   2814  C CB  . SER A 1 374 ? -51.986 -5.284  39.658 1.00 34.68  ? 576 SER A CB  1 
ATOM   2815  O OG  . SER A 1 374 ? -51.701 -5.734  38.348 1.00 38.08  ? 576 SER A OG  1 
ATOM   2816  N N   . TYR A 1 375 ? -50.658 -4.737  42.490 1.00 35.07  ? 577 TYR A N   1 
ATOM   2817  C CA  . TYR A 1 375 ? -50.767 -4.123  43.807 1.00 33.82  ? 577 TYR A CA  1 
ATOM   2818  C C   . TYR A 1 375 ? -52.005 -3.243  43.895 1.00 34.23  ? 577 TYR A C   1 
ATOM   2819  O O   . TYR A 1 375 ? -52.656 -3.175  44.943 1.00 33.88  ? 577 TYR A O   1 
ATOM   2820  C CB  . TYR A 1 375 ? -49.513 -3.307  44.119 1.00 34.49  ? 577 TYR A CB  1 
ATOM   2821  C CG  . TYR A 1 375 ? -49.537 -2.657  45.481 1.00 33.69  ? 577 TYR A CG  1 
ATOM   2822  C CD1 . TYR A 1 375 ? -49.193 -3.373  46.617 1.00 33.76  ? 577 TYR A CD1 1 
ATOM   2823  C CD2 . TYR A 1 375 ? -49.928 -1.336  45.634 1.00 32.72  ? 577 TYR A CD2 1 
ATOM   2824  C CE1 . TYR A 1 375 ? -49.222 -2.787  47.863 1.00 33.65  ? 577 TYR A CE1 1 
ATOM   2825  C CE2 . TYR A 1 375 ? -49.962 -0.744  46.878 1.00 32.16  ? 577 TYR A CE2 1 
ATOM   2826  C CZ  . TYR A 1 375 ? -49.609 -1.473  47.988 1.00 32.71  ? 577 TYR A CZ  1 
ATOM   2827  O OH  . TYR A 1 375 ? -49.642 -0.883  49.229 1.00 32.97  ? 577 TYR A OH  1 
ATOM   2828  N N   . GLY A 1 376 ? -52.346 -2.566  42.804 1.00 35.68  ? 578 GLY A N   1 
ATOM   2829  C CA  . GLY A 1 376 ? -53.490 -1.677  42.807 1.00 35.30  ? 578 GLY A CA  1 
ATOM   2830  C C   . GLY A 1 376 ? -53.488 -0.801  41.572 1.00 35.79  ? 578 GLY A C   1 
ATOM   2831  O O   . GLY A 1 376 ? -52.893 -1.147  40.551 1.00 35.58  ? 578 GLY A O   1 
ATOM   2832  N N   . GLN A 1 377 ? -54.162 0.341   41.688 1.00 38.14  ? 579 GLN A N   1 
ATOM   2833  C CA  . GLN A 1 377 ? -54.314 1.281   40.589 1.00 39.24  ? 579 GLN A CA  1 
ATOM   2834  C C   . GLN A 1 377 ? -53.876 2.670   41.029 1.00 38.35  ? 579 GLN A C   1 
ATOM   2835  O O   . GLN A 1 377 ? -53.973 3.024   42.205 1.00 38.27  ? 579 GLN A O   1 
ATOM   2836  C CB  . GLN A 1 377 ? -55.761 1.326   40.095 1.00 37.27  ? 579 GLN A CB  1 
ATOM   2837  C CG  . GLN A 1 377 ? -56.228 0.042   39.443 1.00 43.60  ? 579 GLN A CG  1 
ATOM   2838  C CD  . GLN A 1 377 ? -57.691 0.084   39.064 1.00 48.89  ? 579 GLN A CD  1 
ATOM   2839  O OE1 . GLN A 1 377 ? -58.479 0.810   39.667 1.00 52.08  ? 579 GLN A OE1 1 
ATOM   2840  N NE2 . GLN A 1 377 ? -58.061 -0.689  38.052 1.00 50.35  ? 579 GLN A NE2 1 
ATOM   2841  N N   . VAL A 1 378 ? -53.384 3.452   40.067 1.00 39.52  ? 580 VAL A N   1 
ATOM   2842  C CA  . VAL A 1 378 ? -52.931 4.814   40.310 1.00 39.42  ? 580 VAL A CA  1 
ATOM   2843  C C   . VAL A 1 378 ? -53.465 5.712   39.206 1.00 40.17  ? 580 VAL A C   1 
ATOM   2844  O O   . VAL A 1 378 ? -53.768 5.263   38.101 1.00 39.90  ? 580 VAL A O   1 
ATOM   2845  C CB  . VAL A 1 378 ? -51.395 4.929   40.373 1.00 35.15  ? 580 VAL A CB  1 
ATOM   2846  C CG1 . VAL A 1 378 ? -50.851 4.174   41.549 1.00 35.58  ? 580 VAL A CG1 1 
ATOM   2847  C CG2 . VAL A 1 378 ? -50.776 4.422   39.085 1.00 34.09  ? 580 VAL A CG2 1 
ATOM   2848  N N   . ALA A 1 379 ? -53.561 7.001   39.514 1.00 40.06  ? 581 ALA A N   1 
ATOM   2849  C CA  . ALA A 1 379 ? -53.947 7.987   38.518 1.00 41.50  ? 581 ALA A CA  1 
ATOM   2850  C C   . ALA A 1 379 ? -52.767 8.277   37.601 1.00 42.51  ? 581 ALA A C   1 
ATOM   2851  O O   . ALA A 1 379 ? -51.665 8.567   38.072 1.00 42.15  ? 581 ALA A O   1 
ATOM   2852  C CB  . ALA A 1 379 ? -54.427 9.269   39.194 1.00 38.55  ? 581 ALA A CB  1 
ATOM   2853  N N   . THR A 1 380 ? -52.979 8.136   36.297 1.00 41.30  ? 582 THR A N   1 
ATOM   2854  C CA  . THR A 1 380 ? -51.943 8.414   35.312 1.00 41.96  ? 582 THR A CA  1 
ATOM   2855  C C   . THR A 1 380 ? -52.085 9.772   34.635 1.00 43.22  ? 582 THR A C   1 
ATOM   2856  O O   . THR A 1 380 ? -51.260 10.100  33.778 1.00 43.86  ? 582 THR A O   1 
ATOM   2857  C CB  . THR A 1 380 ? -51.914 7.310   34.253 1.00 43.52  ? 582 THR A CB  1 
ATOM   2858  O OG1 . THR A 1 380 ? -53.187 7.233   33.603 1.00 45.18  ? 582 THR A OG1 1 
ATOM   2859  C CG2 . THR A 1 380 ? -51.605 5.973   34.901 1.00 41.36  ? 582 THR A CG2 1 
ATOM   2860  N N   . ASN A 1 381 ? -53.099 10.564  34.973 1.00 46.00  ? 583 ASN A N   1 
ATOM   2861  C CA  . ASN A 1 381 ? -53.325 11.818  34.258 1.00 46.88  ? 583 ASN A CA  1 
ATOM   2862  C C   . ASN A 1 381 ? -54.100 12.783  35.148 1.00 48.15  ? 583 ASN A C   1 
ATOM   2863  O O   . ASN A 1 381 ? -54.417 12.480  36.302 1.00 48.39  ? 583 ASN A O   1 
ATOM   2864  C CB  . ASN A 1 381 ? -54.074 11.571  32.944 1.00 50.39  ? 583 ASN A CB  1 
ATOM   2865  C CG  . ASN A 1 381 ? -55.486 11.062  33.164 1.00 50.67  ? 583 ASN A CG  1 
ATOM   2866  O OD1 . ASN A 1 381 ? -55.835 10.604  34.251 1.00 52.11  ? 583 ASN A OD1 1 
ATOM   2867  N ND2 . ASN A 1 381 ? -56.312 11.154  32.132 1.00 50.90  ? 583 ASN A ND2 1 
ATOM   2868  N N   . HIS A 1 382 ? -54.400 13.957  34.595 1.00 50.68  ? 584 HIS A N   1 
ATOM   2869  C CA  . HIS A 1 382 ? -55.350 14.898  35.173 1.00 51.32  ? 584 HIS A CA  1 
ATOM   2870  C C   . HIS A 1 382 ? -56.653 14.816  34.392 1.00 50.96  ? 584 HIS A C   1 
ATOM   2871  O O   . HIS A 1 382 ? -56.646 14.881  33.158 1.00 51.16  ? 584 HIS A O   1 
ATOM   2872  C CB  . HIS A 1 382 ? -54.816 16.329  35.139 1.00 43.84  ? 584 HIS A CB  1 
ATOM   2873  C CG  . HIS A 1 382 ? -53.675 16.579  36.070 1.00 47.20  ? 584 HIS A CG  1 
ATOM   2874  N ND1 . HIS A 1 382 ? -52.851 17.675  35.953 1.00 48.74  ? 584 HIS A ND1 1 
ATOM   2875  C CD2 . HIS A 1 382 ? -53.239 15.893  37.152 1.00 49.42  ? 584 HIS A CD2 1 
ATOM   2876  C CE1 . HIS A 1 382 ? -51.945 17.646  36.914 1.00 49.97  ? 584 HIS A CE1 1 
ATOM   2877  N NE2 . HIS A 1 382 ? -52.159 16.576  37.656 1.00 51.34  ? 584 HIS A NE2 1 
ATOM   2878  N N   . GLN A 1 383 ? -57.762 14.669  35.105 1.00 57.91  ? 585 GLN A N   1 
ATOM   2879  C CA  . GLN A 1 383 ? -59.054 14.749  34.453 1.00 57.07  ? 585 GLN A CA  1 
ATOM   2880  C C   . GLN A 1 383 ? -59.374 16.195  34.096 1.00 57.35  ? 585 GLN A C   1 
ATOM   2881  O O   . GLN A 1 383 ? -58.830 17.144  34.668 1.00 57.13  ? 585 GLN A O   1 
ATOM   2882  C CB  . GLN A 1 383 ? -60.155 14.208  35.355 1.00 59.71  ? 585 GLN A CB  1 
ATOM   2883  C CG  . GLN A 1 383 ? -60.357 15.070  36.574 1.00 57.93  ? 585 GLN A CG  1 
ATOM   2884  C CD  . GLN A 1 383 ? -61.522 14.628  37.407 1.00 56.77  ? 585 GLN A CD  1 
ATOM   2885  O OE1 . GLN A 1 383 ? -61.987 13.497  37.288 1.00 56.54  ? 585 GLN A OE1 1 
ATOM   2886  N NE2 . GLN A 1 383 ? -62.011 15.519  38.260 1.00 56.18  ? 585 GLN A NE2 1 
ATOM   2887  N N   . SER A 1 384 ? -60.281 16.354  33.146 1.00 62.60  ? 586 SER A N   1 
ATOM   2888  C CA  . SER A 1 384 ? -60.780 17.664  32.746 1.00 63.20  ? 586 SER A CA  1 
ATOM   2889  C C   . SER A 1 384 ? -62.066 17.432  31.966 1.00 63.69  ? 586 SER A C   1 
ATOM   2890  O O   . SER A 1 384 ? -62.507 16.294  31.787 1.00 63.07  ? 586 SER A O   1 
ATOM   2891  C CB  . SER A 1 384 ? -59.745 18.436  31.927 1.00 63.96  ? 586 SER A CB  1 
ATOM   2892  O OG  . SER A 1 384 ? -59.442 17.757  30.722 1.00 63.43  ? 586 SER A OG  1 
ATOM   2893  N N   . ALA A 1 385 ? -62.669 18.525  31.500 1.00 62.78  ? 587 ALA A N   1 
ATOM   2894  C CA  . ALA A 1 385 ? -63.864 18.397  30.676 1.00 63.96  ? 587 ALA A CA  1 
ATOM   2895  C C   . ALA A 1 385 ? -63.581 17.608  29.405 1.00 65.40  ? 587 ALA A C   1 
ATOM   2896  O O   . ALA A 1 385 ? -64.470 16.924  28.887 1.00 65.48  ? 587 ALA A O   1 
ATOM   2897  C CB  . ALA A 1 385 ? -64.418 19.779  30.337 1.00 63.91  ? 587 ALA A CB  1 
ATOM   2898  N N   . GLN A 1 386 ? -62.356 17.692  28.888 1.00 66.62  ? 588 GLN A N   1 
ATOM   2899  C CA  . GLN A 1 386 ? -61.967 16.987  27.676 1.00 68.72  ? 588 GLN A CA  1 
ATOM   2900  C C   . GLN A 1 386 ? -61.226 15.680  27.936 1.00 68.71  ? 588 GLN A C   1 
ATOM   2901  O O   . GLN A 1 386 ? -60.910 14.971  26.975 1.00 69.88  ? 588 GLN A O   1 
ATOM   2902  C CB  . GLN A 1 386 ? -61.090 17.889  26.800 1.00 71.02  ? 588 GLN A CB  1 
ATOM   2903  C CG  . GLN A 1 386 ? -61.779 19.149  26.308 1.00 71.02  ? 588 GLN A CG  1 
ATOM   2904  C CD  . GLN A 1 386 ? -61.734 20.271  27.325 1.00 71.02  ? 588 GLN A CD  1 
ATOM   2905  O OE1 . GLN A 1 386 ? -61.194 20.111  28.419 1.00 71.02  ? 588 GLN A OE1 1 
ATOM   2906  N NE2 . GLN A 1 386 ? -62.295 21.419  26.966 1.00 71.02  ? 588 GLN A NE2 1 
ATOM   2907  N N   . ALA A 1 387 ? -60.947 15.337  29.191 1.00 66.43  ? 589 ALA A N   1 
ATOM   2908  C CA  . ALA A 1 387 ? -60.106 14.187  29.495 1.00 64.58  ? 589 ALA A CA  1 
ATOM   2909  C C   . ALA A 1 387 ? -60.721 13.366  30.615 1.00 63.55  ? 589 ALA A C   1 
ATOM   2910  O O   . ALA A 1 387 ? -60.996 13.894  31.695 1.00 63.96  ? 589 ALA A O   1 
ATOM   2911  C CB  . ALA A 1 387 ? -58.693 14.628  29.889 1.00 61.55  ? 589 ALA A CB  1 
ATOM   2912  N N   . GLN A 1 388 ? -60.921 12.077  30.358 1.00 63.87  ? 590 GLN A N   1 
ATOM   2913  C CA  . GLN A 1 388 ? -61.443 11.179  31.373 1.00 63.80  ? 590 GLN A CA  1 
ATOM   2914  C C   . GLN A 1 388 ? -60.376 10.846  32.408 1.00 62.72  ? 590 GLN A C   1 
ATOM   2915  O O   . GLN A 1 388 ? -59.172 10.981  32.172 1.00 62.18  ? 590 GLN A O   1 
ATOM   2916  C CB  . GLN A 1 388 ? -61.967 9.892   30.742 1.00 64.75  ? 590 GLN A CB  1 
ATOM   2917  C CG  . GLN A 1 388 ? -63.208 10.078  29.898 1.00 64.75  ? 590 GLN A CG  1 
ATOM   2918  C CD  . GLN A 1 388 ? -63.675 8.784   29.269 1.00 64.75  ? 590 GLN A CD  1 
ATOM   2919  O OE1 . GLN A 1 388 ? -62.888 7.862   29.061 1.00 64.75  ? 590 GLN A OE1 1 
ATOM   2920  N NE2 . GLN A 1 388 ? -64.965 8.706   28.970 1.00 64.75  ? 590 GLN A NE2 1 
ATOM   2921  N N   . ALA A 1 389 ? -60.838 10.406  33.574 1.00 57.48  ? 591 ALA A N   1 
ATOM   2922  C CA  . ALA A 1 389 ? -59.921 9.941   34.601 1.00 57.24  ? 591 ALA A CA  1 
ATOM   2923  C C   . ALA A 1 389 ? -59.399 8.561   34.234 1.00 57.06  ? 591 ALA A C   1 
ATOM   2924  O O   . ALA A 1 389 ? -60.167 7.609   34.071 1.00 56.71  ? 591 ALA A O   1 
ATOM   2925  C CB  . ALA A 1 389 ? -60.612 9.903   35.962 1.00 54.95  ? 591 ALA A CB  1 
ATOM   2926  N N   . GLN A 1 390 ? -58.083 8.456   34.105 1.00 51.29  ? 592 GLN A N   1 
ATOM   2927  C CA  . GLN A 1 390 ? -57.442 7.227   33.673 1.00 51.79  ? 592 GLN A CA  1 
ATOM   2928  C C   . GLN A 1 390 ? -56.642 6.642   34.823 1.00 51.59  ? 592 GLN A C   1 
ATOM   2929  O O   . GLN A 1 390 ? -56.172 7.370   35.701 1.00 51.01  ? 592 GLN A O   1 
ATOM   2930  C CB  . GLN A 1 390 ? -56.527 7.466   32.474 1.00 54.88  ? 592 GLN A CB  1 
ATOM   2931  C CG  . GLN A 1 390 ? -57.257 7.885   31.219 1.00 54.88  ? 592 GLN A CG  1 
ATOM   2932  C CD  . GLN A 1 390 ? -56.310 8.173   30.076 1.00 54.88  ? 592 GLN A CD  1 
ATOM   2933  O OE1 . GLN A 1 390 ? -55.141 8.484   30.290 1.00 54.88  ? 592 GLN A OE1 1 
ATOM   2934  N NE2 . GLN A 1 390 ? -56.810 8.069   28.852 1.00 54.88  ? 592 GLN A NE2 1 
ATOM   2935  N N   . THR A 1 391 ? -56.502 5.324   34.812 1.00 47.74  ? 593 THR A N   1 
ATOM   2936  C CA  . THR A 1 391 ? -55.707 4.609   35.792 1.00 48.02  ? 593 THR A CA  1 
ATOM   2937  C C   . THR A 1 391 ? -54.766 3.662   35.067 1.00 46.49  ? 593 THR A C   1 
ATOM   2938  O O   . THR A 1 391 ? -54.878 3.434   33.860 1.00 46.60  ? 593 THR A O   1 
ATOM   2939  C CB  . THR A 1 391 ? -56.577 3.823   36.786 1.00 47.80  ? 593 THR A CB  1 
ATOM   2940  O OG1 . THR A 1 391 ? -57.431 2.921   36.073 1.00 50.24  ? 593 THR A OG1 1 
ATOM   2941  C CG2 . THR A 1 391 ? -57.415 4.761   37.637 1.00 47.30  ? 593 THR A CG2 1 
ATOM   2942  N N   . GLY A 1 392 ? -53.824 3.119   35.824 1.00 39.44  ? 594 GLY A N   1 
ATOM   2943  C CA  . GLY A 1 392 ? -52.938 2.102   35.303 1.00 37.52  ? 594 GLY A CA  1 
ATOM   2944  C C   . GLY A 1 392 ? -52.576 1.172   36.433 1.00 36.48  ? 594 GLY A C   1 
ATOM   2945  O O   . GLY A 1 392 ? -52.641 1.536   37.611 1.00 36.57  ? 594 GLY A O   1 
ATOM   2946  N N   . TRP A 1 393 ? -52.189 -0.039  36.063 1.00 34.63  ? 595 TRP A N   1 
ATOM   2947  C CA  . TRP A 1 393 ? -51.970 -1.090  37.038 1.00 33.95  ? 595 TRP A CA  1 
ATOM   2948  C C   . TRP A 1 393 ? -50.554 -1.019  37.580 1.00 32.23  ? 595 TRP A C   1 
ATOM   2949  O O   . TRP A 1 393 ? -49.599 -0.804  36.830 1.00 32.20  ? 595 TRP A O   1 
ATOM   2950  C CB  . TRP A 1 393 ? -52.228 -2.460  36.417 1.00 31.19  ? 595 TRP A CB  1 
ATOM   2951  C CG  . TRP A 1 393 ? -53.654 -2.676  36.034 1.00 34.99  ? 595 TRP A CG  1 
ATOM   2952  C CD1 . TRP A 1 393 ? -54.199 -2.531  34.796 1.00 35.68  ? 595 TRP A CD1 1 
ATOM   2953  C CD2 . TRP A 1 393 ? -54.726 -3.055  36.903 1.00 37.33  ? 595 TRP A CD2 1 
ATOM   2954  N NE1 . TRP A 1 393 ? -55.541 -2.810  34.834 1.00 37.15  ? 595 TRP A NE1 1 
ATOM   2955  C CE2 . TRP A 1 393 ? -55.890 -3.134  36.118 1.00 37.67  ? 595 TRP A CE2 1 
ATOM   2956  C CE3 . TRP A 1 393 ? -54.811 -3.344  38.267 1.00 39.33  ? 595 TRP A CE3 1 
ATOM   2957  C CZ2 . TRP A 1 393 ? -57.127 -3.488  36.651 1.00 38.44  ? 595 TRP A CZ2 1 
ATOM   2958  C CZ3 . TRP A 1 393 ? -56.038 -3.694  38.794 1.00 40.76  ? 595 TRP A CZ3 1 
ATOM   2959  C CH2 . TRP A 1 393 ? -57.179 -3.764  37.988 1.00 40.08  ? 595 TRP A CH2 1 
ATOM   2960  N N   . VAL A 1 394 ? -50.423 -1.210  38.887 1.00 33.09  ? 596 VAL A N   1 
ATOM   2961  C CA  . VAL A 1 394 ? -49.119 -1.250  39.533 1.00 31.46  ? 596 VAL A CA  1 
ATOM   2962  C C   . VAL A 1 394 ? -48.679 -2.705  39.570 1.00 31.62  ? 596 VAL A C   1 
ATOM   2963  O O   . VAL A 1 394 ? -49.212 -3.507  40.339 1.00 31.10  ? 596 VAL A O   1 
ATOM   2964  C CB  . VAL A 1 394 ? -49.176 -0.649  40.941 1.00 30.40  ? 596 VAL A CB  1 
ATOM   2965  C CG1 . VAL A 1 394 ? -47.883 -0.902  41.673 1.00 28.95  ? 596 VAL A CG1 1 
ATOM   2966  C CG2 . VAL A 1 394 ? -49.456 0.836   40.859 1.00 28.33  ? 596 VAL A CG2 1 
ATOM   2967  N N   . GLN A 1 395 ? -47.696 -3.046  38.737 1.00 28.88  ? 597 GLN A N   1 
ATOM   2968  C CA  . GLN A 1 395 ? -47.237 -4.424  38.674 1.00 29.62  ? 597 GLN A CA  1 
ATOM   2969  C C   . GLN A 1 395 ? -46.112 -4.690  39.661 1.00 29.95  ? 597 GLN A C   1 
ATOM   2970  O O   . GLN A 1 395 ? -45.806 -5.851  39.947 1.00 30.87  ? 597 GLN A O   1 
ATOM   2971  C CB  . GLN A 1 395 ? -46.787 -4.754  37.255 1.00 33.64  ? 597 GLN A CB  1 
ATOM   2972  C CG  . GLN A 1 395 ? -47.888 -4.632  36.219 1.00 34.99  ? 597 GLN A CG  1 
ATOM   2973  C CD  . GLN A 1 395 ? -49.082 -5.505  36.530 1.00 33.81  ? 597 GLN A CD  1 
ATOM   2974  O OE1 . GLN A 1 395 ? -48.940 -6.610  37.046 1.00 35.24  ? 597 GLN A OE1 1 
ATOM   2975  N NE2 . GLN A 1 395 ? -50.269 -5.021  36.197 1.00 33.36  ? 597 GLN A NE2 1 
ATOM   2976  N N   . ASN A 1 396 ? -45.488 -3.638  40.178 1.00 28.55  ? 598 ASN A N   1 
ATOM   2977  C CA  . ASN A 1 396 ? -44.510 -3.750  41.246 1.00 28.38  ? 598 ASN A CA  1 
ATOM   2978  C C   . ASN A 1 396 ? -44.587 -2.509  42.116 1.00 28.00  ? 598 ASN A C   1 
ATOM   2979  O O   . ASN A 1 396 ? -44.693 -1.390  41.609 1.00 29.20  ? 598 ASN A O   1 
ATOM   2980  C CB  . ASN A 1 396 ? -43.091 -3.922  40.704 1.00 26.47  ? 598 ASN A CB  1 
ATOM   2981  C CG  . ASN A 1 396 ? -42.661 -2.775  39.821 1.00 27.44  ? 598 ASN A CG  1 
ATOM   2982  O OD1 . ASN A 1 396 ? -43.486 -2.040  39.285 1.00 28.24  ? 598 ASN A OD1 1 
ATOM   2983  N ND2 . ASN A 1 396 ? -41.359 -2.597  39.688 1.00 27.01  ? 598 ASN A ND2 1 
ATOM   2984  N N   . GLN A 1 397 ? -44.515 -2.707  43.427 1.00 29.40  ? 599 GLN A N   1 
ATOM   2985  C CA  . GLN A 1 397 ? -44.611 -1.602  44.370 1.00 27.48  ? 599 GLN A CA  1 
ATOM   2986  C C   . GLN A 1 397 ? -43.480 -1.723  45.372 1.00 27.43  ? 599 GLN A C   1 
ATOM   2987  O O   . GLN A 1 397 ? -43.248 -2.804  45.917 1.00 27.97  ? 599 GLN A O   1 
ATOM   2988  C CB  . GLN A 1 397 ? -45.963 -1.596  45.088 1.00 27.24  ? 599 GLN A CB  1 
ATOM   2989  C CG  . GLN A 1 397 ? -46.169 -0.407  46.017 1.00 26.66  ? 599 GLN A CG  1 
ATOM   2990  C CD  . GLN A 1 397 ? -46.167 0.917   45.281 1.00 26.99  ? 599 GLN A CD  1 
ATOM   2991  O OE1 . GLN A 1 397 ? -46.979 1.141   44.386 1.00 29.13  ? 599 GLN A OE1 1 
ATOM   2992  N NE2 . GLN A 1 397 ? -45.248 1.799   45.650 1.00 26.07  ? 599 GLN A NE2 1 
ATOM   2993  N N   . GLY A 1 398 ? -42.769 -0.625  45.596 1.00 26.68  ? 600 GLY A N   1 
ATOM   2994  C CA  . GLY A 1 398 ? -41.780 -0.572  46.644 1.00 25.26  ? 600 GLY A CA  1 
ATOM   2995  C C   . GLY A 1 398 ? -42.409 -0.248  47.980 1.00 25.07  ? 600 GLY A C   1 
ATOM   2996  O O   . GLY A 1 398 ? -43.625 -0.139  48.125 1.00 24.63  ? 600 GLY A O   1 
ATOM   2997  N N   . ILE A 1 399 ? -41.548 -0.087  48.982 1.00 24.75  ? 601 ILE A N   1 
ATOM   2998  C CA  . ILE A 1 399 ? -42.020 0.228   50.322 1.00 24.03  ? 601 ILE A CA  1 
ATOM   2999  C C   . ILE A 1 399 ? -42.649 1.611   50.332 1.00 23.61  ? 601 ILE A C   1 
ATOM   3000  O O   . ILE A 1 399 ? -42.151 2.542   49.691 1.00 24.28  ? 601 ILE A O   1 
ATOM   3001  C CB  . ILE A 1 399 ? -40.860 0.126   51.327 1.00 23.25  ? 601 ILE A CB  1 
ATOM   3002  C CG1 . ILE A 1 399 ? -40.307 -1.296  51.367 1.00 23.65  ? 601 ILE A CG1 1 
ATOM   3003  C CG2 . ILE A 1 399 ? -41.312 0.536   52.702 1.00 24.71  ? 601 ILE A CG2 1 
ATOM   3004  C CD1 . ILE A 1 399 ? -41.318 -2.320  51.812 1.00 22.51  ? 601 ILE A CD1 1 
ATOM   3005  N N   . LEU A 1 400 ? -43.765 1.743   51.044 1.00 27.04  ? 602 LEU A N   1 
ATOM   3006  C CA  . LEU A 1 400 ? -44.372 3.025   51.356 1.00 26.49  ? 602 LEU A CA  1 
ATOM   3007  C C   . LEU A 1 400 ? -44.520 3.172   52.863 1.00 27.56  ? 602 LEU A C   1 
ATOM   3008  O O   . LEU A 1 400 ? -44.645 2.173   53.577 1.00 27.23  ? 602 LEU A O   1 
ATOM   3009  C CB  . LEU A 1 400 ? -45.749 3.187   50.698 1.00 27.55  ? 602 LEU A CB  1 
ATOM   3010  C CG  . LEU A 1 400 ? -45.818 3.351   49.182 1.00 26.82  ? 602 LEU A CG  1 
ATOM   3011  C CD1 . LEU A 1 400 ? -47.258 3.355   48.725 1.00 26.29  ? 602 LEU A CD1 1 
ATOM   3012  C CD2 . LEU A 1 400 ? -45.136 4.634   48.772 1.00 25.78  ? 602 LEU A CD2 1 
ATOM   3013  N N   . PRO A 1 401 ? -44.486 4.398   53.380 1.00 30.87  ? 603 PRO A N   1 
ATOM   3014  C CA  . PRO A 1 401 ? -44.763 4.598   54.806 1.00 31.06  ? 603 PRO A CA  1 
ATOM   3015  C C   . PRO A 1 401 ? -46.180 4.160   55.143 1.00 31.27  ? 603 PRO A C   1 
ATOM   3016  O O   . PRO A 1 401 ? -47.145 4.564   54.492 1.00 31.68  ? 603 PRO A O   1 
ATOM   3017  C CB  . PRO A 1 401 ? -44.575 6.107   54.991 1.00 27.54  ? 603 PRO A CB  1 
ATOM   3018  C CG  . PRO A 1 401 ? -43.645 6.499   53.893 1.00 30.02  ? 603 PRO A CG  1 
ATOM   3019  C CD  . PRO A 1 401 ? -44.038 5.639   52.731 1.00 28.68  ? 603 PRO A CD  1 
ATOM   3020  N N   . GLY A 1 402 ? -46.301 3.327   56.169 1.00 34.27  ? 604 GLY A N   1 
ATOM   3021  C CA  . GLY A 1 402 ? -47.580 2.782   56.559 1.00 33.24  ? 604 GLY A CA  1 
ATOM   3022  C C   . GLY A 1 402 ? -47.843 1.354   56.138 1.00 33.09  ? 604 GLY A C   1 
ATOM   3023  O O   . GLY A 1 402 ? -48.912 0.824   56.457 1.00 33.33  ? 604 GLY A O   1 
ATOM   3024  N N   . MET A 1 403 ? -46.915 0.717   55.427 1.00 32.77  ? 605 MET A N   1 
ATOM   3025  C CA  . MET A 1 403 ? -47.084 -0.676  55.042 1.00 31.45  ? 605 MET A CA  1 
ATOM   3026  C C   . MET A 1 403 ? -46.769 -1.618  56.195 1.00 30.80  ? 605 MET A C   1 
ATOM   3027  O O   . MET A 1 403 ? -45.936 -1.330  57.057 1.00 31.38  ? 605 MET A O   1 
ATOM   3028  C CB  . MET A 1 403 ? -46.195 -1.041  53.855 1.00 29.11  ? 605 MET A CB  1 
ATOM   3029  C CG  . MET A 1 403 ? -46.654 -0.523  52.515 1.00 29.86  ? 605 MET A CG  1 
ATOM   3030  S SD  . MET A 1 403 ? -45.529 -1.032  51.204 1.00 32.53  ? 605 MET A SD  1 
ATOM   3031  C CE  . MET A 1 403 ? -46.347 -0.346  49.771 1.00 32.81  ? 605 MET A CE  1 
ATOM   3032  N N   . VAL A 1 404 ? -47.454 -2.757  56.195 1.00 34.08  ? 606 VAL A N   1 
ATOM   3033  C CA  . VAL A 1 404 ? -47.149 -3.887  57.059 1.00 33.62  ? 606 VAL A CA  1 
ATOM   3034  C C   . VAL A 1 404 ? -47.149 -5.130  56.182 1.00 33.72  ? 606 VAL A C   1 
ATOM   3035  O O   . VAL A 1 404 ? -47.861 -5.196  55.175 1.00 35.95  ? 606 VAL A O   1 
ATOM   3036  C CB  . VAL A 1 404 ? -48.156 -4.030  58.223 1.00 33.16  ? 606 VAL A CB  1 
ATOM   3037  C CG1 . VAL A 1 404 ? -48.113 -2.807  59.123 1.00 36.90  ? 606 VAL A CG1 1 
ATOM   3038  C CG2 . VAL A 1 404 ? -49.555 -4.252  57.693 1.00 32.24  ? 606 VAL A CG2 1 
ATOM   3039  N N   . TRP A 1 405 ? -46.333 -6.114  56.550 1.00 34.85  ? 607 TRP A N   1 
ATOM   3040  C CA  . TRP A 1 405 ? -46.273 -7.338  55.766 1.00 34.77  ? 607 TRP A CA  1 
ATOM   3041  C C   . TRP A 1 405 ? -45.809 -8.484  56.648 1.00 35.51  ? 607 TRP A C   1 
ATOM   3042  O O   . TRP A 1 405 ? -45.178 -8.278  57.686 1.00 35.17  ? 607 TRP A O   1 
ATOM   3043  C CB  . TRP A 1 405 ? -45.343 -7.190  54.557 1.00 31.01  ? 607 TRP A CB  1 
ATOM   3044  C CG  . TRP A 1 405 ? -43.923 -6.907  54.918 1.00 31.51  ? 607 TRP A CG  1 
ATOM   3045  C CD1 . TRP A 1 405 ? -42.934 -7.821  55.120 1.00 32.43  ? 607 TRP A CD1 1 
ATOM   3046  C CD2 . TRP A 1 405 ? -43.328 -5.622  55.114 1.00 31.48  ? 607 TRP A CD2 1 
ATOM   3047  N NE1 . TRP A 1 405 ? -41.760 -7.187  55.436 1.00 31.95  ? 607 TRP A NE1 1 
ATOM   3048  C CE2 . TRP A 1 405 ? -41.975 -5.835  55.437 1.00 32.36  ? 607 TRP A CE2 1 
ATOM   3049  C CE3 . TRP A 1 405 ? -43.808 -4.313  55.048 1.00 30.80  ? 607 TRP A CE3 1 
ATOM   3050  C CZ2 . TRP A 1 405 ? -41.099 -4.789  55.694 1.00 31.88  ? 607 TRP A CZ2 1 
ATOM   3051  C CZ3 . TRP A 1 405 ? -42.937 -3.278  55.304 1.00 32.35  ? 607 TRP A CZ3 1 
ATOM   3052  C CH2 . TRP A 1 405 ? -41.598 -3.520  55.623 1.00 32.15  ? 607 TRP A CH2 1 
ATOM   3053  N N   . GLN A 1 406 ? -46.133 -9.697  56.214 1.00 35.90  ? 608 GLN A N   1 
ATOM   3054  C CA  . GLN A 1 406 ? -45.615 -10.918 56.808 1.00 37.14  ? 608 GLN A CA  1 
ATOM   3055  C C   . GLN A 1 406 ? -44.450 -11.444 55.984 1.00 37.60  ? 608 GLN A C   1 
ATOM   3056  O O   . GLN A 1 406 ? -44.442 -11.350 54.755 1.00 36.79  ? 608 GLN A O   1 
ATOM   3057  C CB  . GLN A 1 406 ? -46.696 -11.997 56.903 1.00 36.10  ? 608 GLN A CB  1 
ATOM   3058  C CG  . GLN A 1 406 ? -47.787 -11.718 57.909 1.00 41.74  ? 608 GLN A CG  1 
ATOM   3059  C CD  . GLN A 1 406 ? -47.258 -11.637 59.320 1.00 45.39  ? 608 GLN A CD  1 
ATOM   3060  O OE1 . GLN A 1 406 ? -46.397 -12.417 59.719 1.00 48.67  ? 608 GLN A OE1 1 
ATOM   3061  N NE2 . GLN A 1 406 ? -47.764 -10.683 60.084 1.00 41.67  ? 608 GLN A NE2 1 
ATOM   3062  N N   . ASP A 1 407 ? -43.461 -11.996 56.676 1.00 38.99  ? 609 ASP A N   1 
ATOM   3063  C CA  . ASP A 1 407 ? -42.344 -12.636 56.006 1.00 39.77  ? 609 ASP A CA  1 
ATOM   3064  C C   . ASP A 1 407 ? -42.766 -14.023 55.532 1.00 38.86  ? 609 ASP A C   1 
ATOM   3065  O O   . ASP A 1 407 ? -43.895 -14.465 55.752 1.00 37.41  ? 609 ASP A O   1 
ATOM   3066  C CB  . ASP A 1 407 ? -41.139 -12.698 56.940 1.00 37.70  ? 609 ASP A CB  1 
ATOM   3067  C CG  . ASP A 1 407 ? -40.561 -11.327 57.228 1.00 43.07  ? 609 ASP A CG  1 
ATOM   3068  O OD1 . ASP A 1 407 ? -40.842 -10.389 56.453 1.00 44.07  ? 609 ASP A OD1 1 
ATOM   3069  O OD2 . ASP A 1 407 ? -39.840 -11.182 58.237 1.00 45.11  ? 609 ASP A OD2 1 
ATOM   3070  N N   . ARG A 1 408 ? -41.857 -14.726 54.870 1.00 40.66  ? 610 ARG A N   1 
ATOM   3071  C CA  . ARG A 1 408 ? -42.198 -16.046 54.367 1.00 41.00  ? 610 ARG A CA  1 
ATOM   3072  C C   . ARG A 1 408 ? -42.124 -17.077 55.485 1.00 41.02  ? 610 ARG A C   1 
ATOM   3073  O O   . ARG A 1 408 ? -41.265 -17.013 56.367 1.00 40.46  ? 610 ARG A O   1 
ATOM   3074  C CB  . ARG A 1 408 ? -41.275 -16.438 53.218 1.00 38.77  ? 610 ARG A CB  1 
ATOM   3075  C CG  . ARG A 1 408 ? -41.662 -17.731 52.538 1.00 40.19  ? 610 ARG A CG  1 
ATOM   3076  C CD  . ARG A 1 408 ? -40.738 -18.030 51.386 1.00 42.32  ? 610 ARG A CD  1 
ATOM   3077  N NE  . ARG A 1 408 ? -40.844 -17.004 50.357 1.00 45.22  ? 610 ARG A NE  1 
ATOM   3078  C CZ  . ARG A 1 408 ? -41.774 -16.990 49.410 1.00 46.50  ? 610 ARG A CZ  1 
ATOM   3079  N NH1 . ARG A 1 408 ? -42.684 -17.951 49.359 1.00 47.27  ? 610 ARG A NH1 1 
ATOM   3080  N NH2 . ARG A 1 408 ? -41.797 -16.016 48.515 1.00 47.51  ? 610 ARG A NH2 1 
ATOM   3081  N N   . ASP A 1 409 ? -43.048 -18.029 55.443 1.00 41.93  ? 611 ASP A N   1 
ATOM   3082  C CA  . ASP A 1 409 ? -43.157 -19.035 56.483 1.00 42.37  ? 611 ASP A CA  1 
ATOM   3083  C C   . ASP A 1 409 ? -42.022 -20.049 56.369 1.00 42.12  ? 611 ASP A C   1 
ATOM   3084  O O   . ASP A 1 409 ? -41.556 -20.384 55.277 1.00 41.92  ? 611 ASP A O   1 
ATOM   3085  C CB  . ASP A 1 409 ? -44.509 -19.740 56.394 1.00 41.57  ? 611 ASP A CB  1 
ATOM   3086  C CG  . ASP A 1 409 ? -44.772 -20.653 57.568 1.00 43.91  ? 611 ASP A CG  1 
ATOM   3087  O OD1 . ASP A 1 409 ? -43.962 -20.663 58.516 1.00 46.46  ? 611 ASP A OD1 1 
ATOM   3088  O OD2 . ASP A 1 409 ? -45.794 -21.368 57.542 1.00 42.95  ? 611 ASP A OD2 1 
ATOM   3089  N N   . VAL A 1 410 ? -41.579 -20.536 57.519 1.00 42.53  ? 612 VAL A N   1 
ATOM   3090  C CA  . VAL A 1 410 ? -40.535 -21.548 57.587 1.00 41.15  ? 612 VAL A CA  1 
ATOM   3091  C C   . VAL A 1 410 ? -41.179 -22.921 57.487 1.00 39.98  ? 612 VAL A C   1 
ATOM   3092  O O   . VAL A 1 410 ? -42.270 -23.162 58.015 1.00 39.22  ? 612 VAL A O   1 
ATOM   3093  C CB  . VAL A 1 410 ? -39.695 -21.415 58.875 1.00 37.13  ? 612 VAL A CB  1 
ATOM   3094  C CG1 . VAL A 1 410 ? -38.951 -20.090 58.890 1.00 36.49  ? 612 VAL A CG1 1 
ATOM   3095  C CG2 . VAL A 1 410 ? -40.568 -21.556 60.106 1.00 39.94  ? 612 VAL A CG2 1 
ATOM   3096  N N   . TYR A 1 411 ? -40.503 -23.830 56.793 1.00 39.24  ? 613 TYR A N   1 
ATOM   3097  C CA  . TYR A 1 411 ? -41.015 -25.168 56.554 1.00 38.86  ? 613 TYR A CA  1 
ATOM   3098  C C   . TYR A 1 411 ? -40.081 -26.204 57.159 1.00 38.53  ? 613 TYR A C   1 
ATOM   3099  O O   . TYR A 1 411 ? -38.880 -25.975 57.311 1.00 39.89  ? 613 TYR A O   1 
ATOM   3100  C CB  . TYR A 1 411 ? -41.193 -25.430 55.056 1.00 38.89  ? 613 TYR A CB  1 
ATOM   3101  C CG  . TYR A 1 411 ? -42.233 -24.546 54.419 1.00 42.39  ? 613 TYR A CG  1 
ATOM   3102  C CD1 . TYR A 1 411 ? -43.570 -24.909 54.417 1.00 43.79  ? 613 TYR A CD1 1 
ATOM   3103  C CD2 . TYR A 1 411 ? -41.879 -23.346 53.825 1.00 43.46  ? 613 TYR A CD2 1 
ATOM   3104  C CE1 . TYR A 1 411 ? -44.525 -24.103 53.839 1.00 45.85  ? 613 TYR A CE1 1 
ATOM   3105  C CE2 . TYR A 1 411 ? -42.827 -22.534 53.245 1.00 46.96  ? 613 TYR A CE2 1 
ATOM   3106  C CZ  . TYR A 1 411 ? -44.148 -22.917 53.254 1.00 47.44  ? 613 TYR A CZ  1 
ATOM   3107  O OH  . TYR A 1 411 ? -45.098 -22.109 52.676 1.00 49.40  ? 613 TYR A OH  1 
ATOM   3108  N N   . LEU A 1 412 ? -40.656 -27.361 57.497 1.00 37.70  ? 614 LEU A N   1 
ATOM   3109  C CA  . LEU A 1 412 ? -39.875 -28.443 58.090 1.00 37.16  ? 614 LEU A CA  1 
ATOM   3110  C C   . LEU A 1 412 ? -38.726 -28.858 57.178 1.00 38.25  ? 614 LEU A C   1 
ATOM   3111  O O   . LEU A 1 412 ? -37.687 -29.332 57.649 1.00 39.54  ? 614 LEU A O   1 
ATOM   3112  C CB  . LEU A 1 412 ? -40.786 -29.633 58.389 1.00 37.82  ? 614 LEU A CB  1 
ATOM   3113  C CG  . LEU A 1 412 ? -40.263 -30.795 59.237 1.00 37.56  ? 614 LEU A CG  1 
ATOM   3114  C CD1 . LEU A 1 412 ? -39.257 -30.316 60.266 1.00 37.72  ? 614 LEU A CD1 1 
ATOM   3115  C CD2 . LEU A 1 412 ? -41.418 -31.490 59.931 1.00 36.08  ? 614 LEU A CD2 1 
ATOM   3116  N N   . GLN A 1 413 ? -38.891 -28.685 55.871 1.00 39.25  ? 615 GLN A N   1 
ATOM   3117  C CA  . GLN A 1 413 ? -37.834 -28.982 54.919 1.00 39.10  ? 615 GLN A CA  1 
ATOM   3118  C C   . GLN A 1 413 ? -36.996 -27.763 54.560 1.00 38.67  ? 615 GLN A C   1 
ATOM   3119  O O   . GLN A 1 413 ? -36.091 -27.881 53.729 1.00 39.26  ? 615 GLN A O   1 
ATOM   3120  C CB  . GLN A 1 413 ? -38.424 -29.565 53.631 1.00 38.10  ? 615 GLN A CB  1 
ATOM   3121  C CG  . GLN A 1 413 ? -39.192 -30.857 53.806 1.00 43.50  ? 615 GLN A CG  1 
ATOM   3122  C CD  . GLN A 1 413 ? -40.637 -30.620 54.185 1.00 46.39  ? 615 GLN A CD  1 
ATOM   3123  O OE1 . GLN A 1 413 ? -41.074 -29.479 54.319 1.00 45.14  ? 615 GLN A OE1 1 
ATOM   3124  N NE2 . GLN A 1 413 ? -41.390 -31.698 54.358 1.00 48.98  ? 615 GLN A NE2 1 
ATOM   3125  N N   . GLY A 1 414 ? -37.269 -26.606 55.157 1.00 38.58  ? 616 GLY A N   1 
ATOM   3126  C CA  . GLY A 1 414 ? -36.703 -25.362 54.696 1.00 36.94  ? 616 GLY A CA  1 
ATOM   3127  C C   . GLY A 1 414 ? -35.510 -24.883 55.495 1.00 35.90  ? 616 GLY A C   1 
ATOM   3128  O O   . GLY A 1 414 ? -35.158 -25.441 56.538 1.00 35.64  ? 616 GLY A O   1 
ATOM   3129  N N   . PRO A 1 415 ? -34.864 -23.826 55.010 1.00 33.00  ? 617 PRO A N   1 
ATOM   3130  C CA  . PRO A 1 415 ? -33.673 -23.308 55.687 1.00 33.19  ? 617 PRO A CA  1 
ATOM   3131  C C   . PRO A 1 415 ? -34.019 -22.585 56.978 1.00 33.56  ? 617 PRO A C   1 
ATOM   3132  O O   . PRO A 1 415 ? -35.157 -22.181 57.213 1.00 33.60  ? 617 PRO A O   1 
ATOM   3133  C CB  . PRO A 1 415 ? -33.081 -22.344 54.658 1.00 32.92  ? 617 PRO A CB  1 
ATOM   3134  C CG  . PRO A 1 415 ? -34.245 -21.905 53.854 1.00 33.64  ? 617 PRO A CG  1 
ATOM   3135  C CD  . PRO A 1 415 ? -35.166 -23.083 53.776 1.00 32.25  ? 617 PRO A CD  1 
ATOM   3136  N N   . ILE A 1 416 ? -32.998 -22.418 57.818 1.00 33.73  ? 618 ILE A N   1 
ATOM   3137  C CA  . ILE A 1 416 ? -33.156 -21.797 59.129 1.00 31.96  ? 618 ILE A CA  1 
ATOM   3138  C C   . ILE A 1 416 ? -32.618 -20.373 59.104 1.00 32.79  ? 618 ILE A C   1 
ATOM   3139  O O   . ILE A 1 416 ? -33.358 -19.418 59.351 1.00 33.26  ? 618 ILE A O   1 
ATOM   3140  C CB  . ILE A 1 416 ? -32.465 -22.619 60.230 1.00 35.44  ? 618 ILE A CB  1 
ATOM   3141  C CG1 . ILE A 1 416 ? -33.128 -23.985 60.366 1.00 34.68  ? 618 ILE A CG1 1 
ATOM   3142  C CG2 . ILE A 1 416 ? -32.534 -21.889 61.555 1.00 31.91  ? 618 ILE A CG2 1 
ATOM   3143  C CD1 . ILE A 1 416 ? -32.366 -24.929 61.252 1.00 33.24  ? 618 ILE A CD1 1 
ATOM   3144  N N   . TRP A 1 417 ? -31.327 -20.216 58.835 1.00 34.00  ? 619 TRP A N   1 
ATOM   3145  C CA  . TRP A 1 417 ? -30.679 -18.914 58.865 1.00 34.26  ? 619 TRP A CA  1 
ATOM   3146  C C   . TRP A 1 417 ? -30.058 -18.601 57.513 1.00 34.83  ? 619 TRP A C   1 
ATOM   3147  O O   . TRP A 1 417 ? -29.912 -19.465 56.647 1.00 34.37  ? 619 TRP A O   1 
ATOM   3148  C CB  . TRP A 1 417 ? -29.588 -18.844 59.938 1.00 30.80  ? 619 TRP A CB  1 
ATOM   3149  C CG  . TRP A 1 417 ? -28.475 -19.800 59.682 1.00 32.08  ? 619 TRP A CG  1 
ATOM   3150  C CD1 . TRP A 1 417 ? -27.390 -19.597 58.884 1.00 33.39  ? 619 TRP A CD1 1 
ATOM   3151  C CD2 . TRP A 1 417 ? -28.318 -21.101 60.248 1.00 32.10  ? 619 TRP A CD2 1 
ATOM   3152  N NE1 . TRP A 1 417 ? -26.579 -20.701 58.898 1.00 34.08  ? 619 TRP A NE1 1 
ATOM   3153  C CE2 . TRP A 1 417 ? -27.126 -21.638 59.732 1.00 33.18  ? 619 TRP A CE2 1 
ATOM   3154  C CE3 . TRP A 1 417 ? -29.075 -21.867 61.135 1.00 30.75  ? 619 TRP A CE3 1 
ATOM   3155  C CZ2 . TRP A 1 417 ? -26.674 -22.903 60.075 1.00 33.69  ? 619 TRP A CZ2 1 
ATOM   3156  C CZ3 . TRP A 1 417 ? -28.627 -23.120 61.470 1.00 32.22  ? 619 TRP A CZ3 1 
ATOM   3157  C CH2 . TRP A 1 417 ? -27.439 -23.627 60.942 1.00 33.76  ? 619 TRP A CH2 1 
ATOM   3158  N N   . ALA A 1 418 ? -29.700 -17.333 57.343 1.00 29.99  ? 620 ALA A N   1 
ATOM   3159  C CA  . ALA A 1 418 ? -28.882 -16.894 56.227 1.00 31.17  ? 620 ALA A CA  1 
ATOM   3160  C C   . ALA A 1 418 ? -27.965 -15.782 56.711 1.00 32.15  ? 620 ALA A C   1 
ATOM   3161  O O   . ALA A 1 418 ? -28.241 -15.114 57.708 1.00 32.01  ? 620 ALA A O   1 
ATOM   3162  C CB  . ALA A 1 418 ? -29.735 -16.416 55.050 1.00 29.60  ? 620 ALA A CB  1 
ATOM   3163  N N   . LYS A 1 419 ? -26.865 -15.590 55.994 1.00 27.34  ? 621 LYS A N   1 
ATOM   3164  C CA  . LYS A 1 419 ? -25.927 -14.523 56.307 1.00 27.92  ? 621 LYS A CA  1 
ATOM   3165  C C   . LYS A 1 419 ? -26.351 -13.263 55.571 1.00 28.78  ? 621 LYS A C   1 
ATOM   3166  O O   . LYS A 1 419 ? -26.393 -13.245 54.337 1.00 28.81  ? 621 LYS A O   1 
ATOM   3167  C CB  . LYS A 1 419 ? -24.501 -14.902 55.917 1.00 23.41  ? 621 LYS A CB  1 
ATOM   3168  C CG  . LYS A 1 419 ? -23.474 -13.855 56.298 1.00 24.78  ? 621 LYS A CG  1 
ATOM   3169  C CD  . LYS A 1 419 ? -22.064 -14.345 56.060 1.00 26.82  ? 621 LYS A CD  1 
ATOM   3170  C CE  . LYS A 1 419 ? -21.053 -13.278 56.417 1.00 29.73  ? 621 LYS A CE  1 
ATOM   3171  N NZ  . LYS A 1 419 ? -21.092 -12.153 55.449 1.00 32.42  ? 621 LYS A NZ  1 
ATOM   3172  N N   . ILE A 1 420 ? -26.674 -12.224 56.324 1.00 24.59  ? 622 ILE A N   1 
ATOM   3173  C CA  . ILE A 1 420 ? -26.953 -10.920 55.718 1.00 25.10  ? 622 ILE A CA  1 
ATOM   3174  C C   . ILE A 1 420 ? -25.699 -10.442 54.998 1.00 27.02  ? 622 ILE A C   1 
ATOM   3175  O O   . ILE A 1 420 ? -24.631 -10.357 55.627 1.00 27.84  ? 622 ILE A O   1 
ATOM   3176  C CB  . ILE A 1 420 ? -27.372 -9.920  56.790 1.00 28.20  ? 622 ILE A CB  1 
ATOM   3177  C CG1 . ILE A 1 420 ? -28.645 -10.376 57.496 1.00 27.03  ? 622 ILE A CG1 1 
ATOM   3178  C CG2 . ILE A 1 420 ? -27.594 -8.559  56.173 1.00 28.19  ? 622 ILE A CG2 1 
ATOM   3179  C CD1 . ILE A 1 420 ? -28.907 -9.621  58.771 1.00 25.82  ? 622 ILE A CD1 1 
ATOM   3180  N N   . PRO A 1 421 ? -25.761 -10.140 53.703 1.00 23.09  ? 623 PRO A N   1 
ATOM   3181  C CA  . PRO A 1 421 ? -24.564 -9.649  53.012 1.00 24.02  ? 623 PRO A CA  1 
ATOM   3182  C C   . PRO A 1 421 ? -24.015 -8.406  53.689 1.00 26.04  ? 623 PRO A C   1 
ATOM   3183  O O   . PRO A 1 421 ? -24.750 -7.625  54.296 1.00 26.69  ? 623 PRO A O   1 
ATOM   3184  C CB  . PRO A 1 421 ? -25.073 -9.340  51.601 1.00 22.78  ? 623 PRO A CB  1 
ATOM   3185  C CG  . PRO A 1 421 ? -26.234 -10.239 51.430 1.00 22.74  ? 623 PRO A CG  1 
ATOM   3186  C CD  . PRO A 1 421 ? -26.893 -10.306 52.778 1.00 22.25  ? 623 PRO A CD  1 
ATOM   3187  N N   . HIS A 1 422 ? -22.705 -8.223  53.580 1.00 23.89  ? 624 HIS A N   1 
ATOM   3188  C CA  . HIS A 1 422 ? -22.040 -7.098  54.221 1.00 25.33  ? 624 HIS A CA  1 
ATOM   3189  C C   . HIS A 1 422 ? -22.044 -5.949  53.227 1.00 24.00  ? 624 HIS A C   1 
ATOM   3190  O O   . HIS A 1 422 ? -21.312 -5.977  52.236 1.00 23.40  ? 624 HIS A O   1 
ATOM   3191  C CB  . HIS A 1 422 ? -20.616 -7.464  54.626 1.00 23.08  ? 624 HIS A CB  1 
ATOM   3192  C CG  . HIS A 1 422 ? -19.913 -6.388  55.389 1.00 28.15  ? 624 HIS A CG  1 
ATOM   3193  N ND1 . HIS A 1 422 ? -20.290 -6.011  56.659 1.00 31.06  ? 624 HIS A ND1 1 
ATOM   3194  C CD2 . HIS A 1 422 ? -18.881 -5.582  55.049 1.00 30.37  ? 624 HIS A CD2 1 
ATOM   3195  C CE1 . HIS A 1 422 ? -19.503 -5.037  57.078 1.00 32.61  ? 624 HIS A CE1 1 
ATOM   3196  N NE2 . HIS A 1 422 ? -18.640 -4.757  56.120 1.00 32.93  ? 624 HIS A NE2 1 
ATOM   3197  N N   . THR A 1 423 ? -22.851 -4.931  53.503 1.00 21.48  ? 625 THR A N   1 
ATOM   3198  C CA  . THR A 1 423 ? -23.097 -3.860  52.551 1.00 21.62  ? 625 THR A CA  1 
ATOM   3199  C C   . THR A 1 423 ? -23.315 -2.564  53.315 1.00 21.78  ? 625 THR A C   1 
ATOM   3200  O O   . THR A 1 423 ? -23.514 -2.560  54.531 1.00 21.53  ? 625 THR A O   1 
ATOM   3201  C CB  . THR A 1 423 ? -24.302 -4.160  51.644 1.00 21.13  ? 625 THR A CB  1 
ATOM   3202  O OG1 . THR A 1 423 ? -25.455 -4.445  52.445 1.00 20.64  ? 625 THR A OG1 1 
ATOM   3203  C CG2 . THR A 1 423 ? -24.029 -5.328  50.707 1.00 20.10  ? 625 THR A CG2 1 
ATOM   3204  N N   . ASP A 1 424 ? -23.253 -1.453  52.579 1.00 21.64  ? 626 ASP A N   1 
ATOM   3205  C CA  . ASP A 1 424 ? -23.532 -0.148  53.169 1.00 22.02  ? 626 ASP A CA  1 
ATOM   3206  C C   . ASP A 1 424 ? -24.915 -0.109  53.801 1.00 20.97  ? 626 ASP A C   1 
ATOM   3207  O O   . ASP A 1 424 ? -25.087 0.405   54.911 1.00 21.91  ? 626 ASP A O   1 
ATOM   3208  C CB  . ASP A 1 424 ? -23.398 0.944   52.112 1.00 21.46  ? 626 ASP A CB  1 
ATOM   3209  C CG  . ASP A 1 424 ? -21.968 1.241   51.776 1.00 25.37  ? 626 ASP A CG  1 
ATOM   3210  O OD1 . ASP A 1 424 ? -21.099 0.885   52.591 1.00 29.20  ? 626 ASP A OD1 1 
ATOM   3211  O OD2 . ASP A 1 424 ? -21.710 1.823   50.705 1.00 27.53  ? 626 ASP A OD2 1 
ATOM   3212  N N   . GLY A 1 425 ? -25.914 -0.649  53.114 1.00 21.27  ? 627 GLY A N   1 
ATOM   3213  C CA  . GLY A 1 425 ? -27.261 -0.620  53.645 1.00 18.77  ? 627 GLY A CA  1 
ATOM   3214  C C   . GLY A 1 425 ? -28.112 -1.752  53.120 1.00 18.09  ? 627 GLY A C   1 
ATOM   3215  O O   . GLY A 1 425 ? -27.870 -2.304  52.043 1.00 18.20  ? 627 GLY A O   1 
ATOM   3216  N N   . ASN A 1 426 ? -29.120 -2.091  53.916 1.00 22.51  ? 628 ASN A N   1 
ATOM   3217  C CA  . ASN A 1 426 ? -30.130 -3.072  53.558 1.00 22.13  ? 628 ASN A CA  1 
ATOM   3218  C C   . ASN A 1 426 ? -31.448 -2.639  54.177 1.00 21.54  ? 628 ASN A C   1 
ATOM   3219  O O   . ASN A 1 426 ? -31.488 -1.747  55.028 1.00 20.88  ? 628 ASN A O   1 
ATOM   3220  C CB  . ASN A 1 426 ? -29.732 -4.488  54.006 1.00 23.58  ? 628 ASN A CB  1 
ATOM   3221  C CG  . ASN A 1 426 ? -29.500 -4.597  55.509 1.00 22.98  ? 628 ASN A CG  1 
ATOM   3222  O OD1 . ASN A 1 426 ? -30.163 -3.946  56.312 1.00 21.31  ? 628 ASN A OD1 1 
ATOM   3223  N ND2 . ASN A 1 426 ? -28.540 -5.426  55.889 1.00 23.89  ? 628 ASN A ND2 1 
ATOM   3224  N N   . PHE A 1 427 ? -32.531 -3.263  53.732 1.00 23.72  ? 629 PHE A N   1 
ATOM   3225  C CA  . PHE A 1 427 ? -33.830 -3.063  54.354 1.00 23.31  ? 629 PHE A CA  1 
ATOM   3226  C C   . PHE A 1 427 ? -34.463 -4.411  54.640 1.00 24.81  ? 629 PHE A C   1 
ATOM   3227  O O   . PHE A 1 427 ? -34.523 -5.271  53.756 1.00 24.79  ? 629 PHE A O   1 
ATOM   3228  C CB  . PHE A 1 427 ? -34.762 -2.227  53.482 1.00 24.22  ? 629 PHE A CB  1 
ATOM   3229  C CG  . PHE A 1 427 ? -36.136 -2.071  54.058 1.00 24.65  ? 629 PHE A CG  1 
ATOM   3230  C CD1 . PHE A 1 427 ? -36.376 -1.162  55.072 1.00 23.03  ? 629 PHE A CD1 1 
ATOM   3231  C CD2 . PHE A 1 427 ? -37.186 -2.841  53.596 1.00 24.34  ? 629 PHE A CD2 1 
ATOM   3232  C CE1 . PHE A 1 427 ? -37.634 -1.024  55.610 1.00 22.95  ? 629 PHE A CE1 1 
ATOM   3233  C CE2 . PHE A 1 427 ? -38.444 -2.705  54.130 1.00 24.43  ? 629 PHE A CE2 1 
ATOM   3234  C CZ  . PHE A 1 427 ? -38.669 -1.795  55.139 1.00 23.87  ? 629 PHE A CZ  1 
ATOM   3235  N N   . HIS A 1 428 ? -34.943 -4.574  55.869 1.00 26.07  ? 630 HIS A N   1 
ATOM   3236  C CA  . HIS A 1 428 ? -35.609 -5.767  56.372 1.00 27.18  ? 630 HIS A CA  1 
ATOM   3237  C C   . HIS A 1 428 ? -34.790 -6.994  55.990 1.00 27.71  ? 630 HIS A C   1 
ATOM   3238  O O   . HIS A 1 428 ? -35.180 -7.760  55.101 1.00 28.31  ? 630 HIS A O   1 
ATOM   3239  C CB  . HIS A 1 428 ? -37.036 -5.859  55.837 1.00 32.70  ? 630 HIS A CB  1 
ATOM   3240  C CG  . HIS A 1 428 ? -37.890 -6.835  56.581 1.00 34.14  ? 630 HIS A CG  1 
ATOM   3241  N ND1 . HIS A 1 428 ? -38.203 -6.673  57.913 1.00 34.73  ? 630 HIS A ND1 1 
ATOM   3242  C CD2 . HIS A 1 428 ? -38.491 -7.982  56.189 1.00 34.40  ? 630 HIS A CD2 1 
ATOM   3243  C CE1 . HIS A 1 428 ? -38.965 -7.675  58.308 1.00 35.22  ? 630 HIS A CE1 1 
ATOM   3244  N NE2 . HIS A 1 428 ? -39.154 -8.484  57.282 1.00 35.02  ? 630 HIS A NE2 1 
ATOM   3245  N N   . PRO A 1 429 ? -33.652 -7.199  56.641 1.00 29.85  ? 631 PRO A N   1 
ATOM   3246  C CA  . PRO A 1 429 ? -32.677 -8.203  56.192 1.00 29.47  ? 631 PRO A CA  1 
ATOM   3247  C C   . PRO A 1 429 ? -33.176 -9.640  56.157 1.00 29.45  ? 631 PRO A C   1 
ATOM   3248  O O   . PRO A 1 429 ? -32.455 -10.511 55.664 1.00 30.78  ? 631 PRO A O   1 
ATOM   3249  C CB  . PRO A 1 429 ? -31.537 -8.036  57.200 1.00 30.76  ? 631 PRO A CB  1 
ATOM   3250  C CG  . PRO A 1 429 ? -32.184 -7.482  58.411 1.00 30.19  ? 631 PRO A CG  1 
ATOM   3251  C CD  . PRO A 1 429 ? -33.234 -6.553  57.895 1.00 30.25  ? 631 PRO A CD  1 
ATOM   3252  N N   . SER A 1 430 ? -34.350 -9.912  56.719 1.00 31.39  ? 632 SER A N   1 
ATOM   3253  C CA  . SER A 1 430 ? -34.886 -11.266 56.746 1.00 30.77  ? 632 SER A CA  1 
ATOM   3254  C C   . SER A 1 430 ? -34.814 -11.897 55.354 1.00 30.07  ? 632 SER A C   1 
ATOM   3255  O O   . SER A 1 430 ? -35.247 -11.276 54.373 1.00 30.13  ? 632 SER A O   1 
ATOM   3256  C CB  . SER A 1 430 ? -36.333 -11.249 57.241 1.00 29.42  ? 632 SER A CB  1 
ATOM   3257  O OG  . SER A 1 430 ? -36.893 -12.550 57.234 1.00 33.77  ? 632 SER A OG  1 
ATOM   3258  N N   . PRO A 1 431 ? -34.278 -13.111 55.227 1.00 29.71  ? 633 PRO A N   1 
ATOM   3259  C CA  . PRO A 1 431 ? -34.030 -13.676 53.897 1.00 29.42  ? 633 PRO A CA  1 
ATOM   3260  C C   . PRO A 1 431 ? -35.309 -14.070 53.180 1.00 29.48  ? 633 PRO A C   1 
ATOM   3261  O O   . PRO A 1 431 ? -36.332 -14.378 53.795 1.00 29.90  ? 633 PRO A O   1 
ATOM   3262  C CB  . PRO A 1 431 ? -33.164 -14.904 54.196 1.00 28.67  ? 633 PRO A CB  1 
ATOM   3263  C CG  . PRO A 1 431 ? -33.525 -15.290 55.574 1.00 29.84  ? 633 PRO A CG  1 
ATOM   3264  C CD  . PRO A 1 431 ? -33.817 -14.009 56.299 1.00 28.91  ? 633 PRO A CD  1 
ATOM   3265  N N   . LEU A 1 432 ? -35.226 -14.083 51.848 1.00 32.24  ? 634 LEU A N   1 
ATOM   3266  C CA  . LEU A 1 432 ? -36.412 -14.283 51.025 1.00 32.24  ? 634 LEU A CA  1 
ATOM   3267  C C   . LEU A 1 432 ? -36.866 -15.736 50.969 1.00 33.51  ? 634 LEU A C   1 
ATOM   3268  O O   . LEU A 1 432 ? -38.063 -15.983 50.798 1.00 33.54  ? 634 LEU A O   1 
ATOM   3269  C CB  . LEU A 1 432 ? -36.166 -13.759 49.613 1.00 31.54  ? 634 LEU A CB  1 
ATOM   3270  C CG  . LEU A 1 432 ? -35.992 -12.244 49.520 1.00 29.61  ? 634 LEU A CG  1 
ATOM   3271  C CD1 . LEU A 1 432 ? -35.672 -11.833 48.097 1.00 28.80  ? 634 LEU A CD1 1 
ATOM   3272  C CD2 . LEU A 1 432 ? -37.234 -11.539 50.019 1.00 26.84  ? 634 LEU A CD2 1 
ATOM   3273  N N   . MET A 1 433 ? -35.959 -16.700 51.116 1.00 32.37  ? 635 MET A N   1 
ATOM   3274  C CA  . MET A 1 433 ? -36.382 -18.094 51.155 1.00 33.16  ? 635 MET A CA  1 
ATOM   3275  C C   . MET A 1 433 ? -36.907 -18.509 52.521 1.00 33.32  ? 635 MET A C   1 
ATOM   3276  O O   . MET A 1 433 ? -37.314 -19.663 52.684 1.00 32.83  ? 635 MET A O   1 
ATOM   3277  C CB  . MET A 1 433 ? -35.240 -19.027 50.743 1.00 27.09  ? 635 MET A CB  1 
ATOM   3278  C CG  . MET A 1 433 ? -34.863 -18.949 49.276 1.00 29.49  ? 635 MET A CG  1 
ATOM   3279  S SD  . MET A 1 433 ? -33.637 -20.178 48.793 1.00 35.21  ? 635 MET A SD  1 
ATOM   3280  C CE  . MET A 1 433 ? -32.145 -19.488 49.488 1.00 34.29  ? 635 MET A CE  1 
ATOM   3281  N N   . GLY A 1 434 ? -36.910 -17.611 53.491 1.00 32.55  ? 636 GLY A N   1 
ATOM   3282  C CA  . GLY A 1 434 ? -37.431 -17.897 54.807 1.00 31.60  ? 636 GLY A CA  1 
ATOM   3283  C C   . GLY A 1 434 ? -36.321 -18.115 55.821 1.00 31.38  ? 636 GLY A C   1 
ATOM   3284  O O   . GLY A 1 434 ? -35.207 -18.536 55.496 1.00 32.62  ? 636 GLY A O   1 
ATOM   3285  N N   . GLY A 1 435 ? -36.647 -17.837 57.073 1.00 33.03  ? 637 GLY A N   1 
ATOM   3286  C CA  . GLY A 1 435 ? -35.698 -17.980 58.148 1.00 31.24  ? 637 GLY A CA  1 
ATOM   3287  C C   . GLY A 1 435 ? -35.169 -16.663 58.676 1.00 29.80  ? 637 GLY A C   1 
ATOM   3288  O O   . GLY A 1 435 ? -35.674 -15.578 58.381 1.00 29.41  ? 637 GLY A O   1 
ATOM   3289  N N   . PHE A 1 436 ? -34.124 -16.777 59.490 1.00 31.97  ? 638 PHE A N   1 
ATOM   3290  C CA  . PHE A 1 436 ? -33.605 -15.680 60.297 1.00 31.75  ? 638 PHE A CA  1 
ATOM   3291  C C   . PHE A 1 436 ? -32.418 -15.040 59.593 1.00 33.42  ? 638 PHE A C   1 
ATOM   3292  O O   . PHE A 1 436 ? -31.421 -15.714 59.317 1.00 35.35  ? 638 PHE A O   1 
ATOM   3293  C CB  . PHE A 1 436 ? -33.180 -16.188 61.673 1.00 36.20  ? 638 PHE A CB  1 
ATOM   3294  C CG  . PHE A 1 436 ? -34.275 -16.865 62.435 1.00 35.64  ? 638 PHE A CG  1 
ATOM   3295  C CD1 . PHE A 1 436 ? -35.159 -16.137 63.204 1.00 35.02  ? 638 PHE A CD1 1 
ATOM   3296  C CD2 . PHE A 1 436 ? -34.422 -18.239 62.376 1.00 35.30  ? 638 PHE A CD2 1 
ATOM   3297  C CE1 . PHE A 1 436 ? -36.165 -16.767 63.906 1.00 35.43  ? 638 PHE A CE1 1 
ATOM   3298  C CE2 . PHE A 1 436 ? -35.425 -18.872 63.069 1.00 35.56  ? 638 PHE A CE2 1 
ATOM   3299  C CZ  . PHE A 1 436 ? -36.297 -18.138 63.837 1.00 35.15  ? 638 PHE A CZ  1 
ATOM   3300  N N   . GLY A 1 437 ? -32.523 -13.746 59.303 1.00 32.39  ? 639 GLY A N   1 
ATOM   3301  C CA  . GLY A 1 437 ? -31.388 -12.988 58.808 1.00 32.78  ? 639 GLY A CA  1 
ATOM   3302  C C   . GLY A 1 437 ? -30.407 -12.689 59.929 1.00 33.86  ? 639 GLY A C   1 
ATOM   3303  O O   . GLY A 1 437 ? -30.792 -12.248 61.010 1.00 33.89  ? 639 GLY A O   1 
ATOM   3304  N N   . MET A 1 438 ? -29.127 -12.921 59.652 1.00 30.78  ? 640 MET A N   1 
ATOM   3305  C CA  . MET A 1 438 ? -28.095 -12.731 60.659 1.00 31.39  ? 640 MET A CA  1 
ATOM   3306  C C   . MET A 1 438 ? -26.850 -12.155 60.004 1.00 32.10  ? 640 MET A C   1 
ATOM   3307  O O   . MET A 1 438 ? -26.440 -12.611 58.934 1.00 32.13  ? 640 MET A O   1 
ATOM   3308  C CB  . MET A 1 438 ? -27.760 -14.050 61.365 1.00 33.98  ? 640 MET A CB  1 
ATOM   3309  C CG  . MET A 1 438 ? -28.914 -14.627 62.160 1.00 38.49  ? 640 MET A CG  1 
ATOM   3310  S SD  . MET A 1 438 ? -28.549 -16.201 62.943 1.00 42.96  ? 640 MET A SD  1 
ATOM   3311  C CE  . MET A 1 438 ? -27.455 -15.651 64.240 1.00 42.85  ? 640 MET A CE  1 
ATOM   3312  N N   . LYS A 1 439 ? -26.258 -11.146 60.644 1.00 32.58  ? 641 LYS A N   1 
ATOM   3313  C CA  . LYS A 1 439 ? -24.962 -10.653 60.196 1.00 34.52  ? 641 LYS A CA  1 
ATOM   3314  C C   . LYS A 1 439 ? -23.845 -11.638 60.484 1.00 34.47  ? 641 LYS A C   1 
ATOM   3315  O O   . LYS A 1 439 ? -22.958 -11.816 59.644 1.00 35.19  ? 641 LYS A O   1 
ATOM   3316  C CB  . LYS A 1 439 ? -24.627 -9.316  60.857 1.00 32.79  ? 641 LYS A CB  1 
ATOM   3317  C CG  . LYS A 1 439 ? -25.435 -8.141  60.357 1.00 38.69  ? 641 LYS A CG  1 
ATOM   3318  C CD  . LYS A 1 439 ? -24.866 -6.836  60.884 1.00 45.11  ? 641 LYS A CD  1 
ATOM   3319  C CE  . LYS A 1 439 ? -24.987 -6.751  62.398 1.00 47.48  ? 641 LYS A CE  1 
ATOM   3320  N NZ  . LYS A 1 439 ? -24.516 -5.442  62.927 1.00 48.23  ? 641 LYS A NZ  1 
ATOM   3321  N N   . HIS A 1 440 ? -23.867 -12.273 61.651 1.00 34.76  ? 642 HIS A N   1 
ATOM   3322  C CA  . HIS A 1 440 ? -22.890 -13.289 62.028 1.00 34.60  ? 642 HIS A CA  1 
ATOM   3323  C C   . HIS A 1 440 ? -23.649 -14.584 62.267 1.00 32.95  ? 642 HIS A C   1 
ATOM   3324  O O   . HIS A 1 440 ? -23.962 -14.935 63.412 1.00 33.06  ? 642 HIS A O   1 
ATOM   3325  C CB  . HIS A 1 440 ? -22.092 -12.862 63.260 1.00 28.71  ? 642 HIS A CB  1 
ATOM   3326  C CG  . HIS A 1 440 ? -21.351 -11.573 63.083 1.00 33.82  ? 642 HIS A CG  1 
ATOM   3327  N ND1 . HIS A 1 440 ? -20.284 -11.440 62.221 1.00 35.08  ? 642 HIS A ND1 1 
ATOM   3328  C CD2 . HIS A 1 440 ? -21.516 -10.362 63.665 1.00 34.91  ? 642 HIS A CD2 1 
ATOM   3329  C CE1 . HIS A 1 440 ? -19.829 -10.202 62.273 1.00 36.27  ? 642 HIS A CE1 1 
ATOM   3330  N NE2 . HIS A 1 440 ? -20.559 -9.527  63.142 1.00 37.49  ? 642 HIS A NE2 1 
ATOM   3331  N N   . PRO A 1 441 ? -23.973 -15.315 61.206 1.00 33.73  ? 643 PRO A N   1 
ATOM   3332  C CA  . PRO A 1 441 ? -24.725 -16.560 61.350 1.00 32.14  ? 643 PRO A CA  1 
ATOM   3333  C C   . PRO A 1 441 ? -23.857 -17.644 61.962 1.00 31.40  ? 643 PRO A C   1 
ATOM   3334  O O   . PRO A 1 441 ? -22.687 -17.391 62.289 1.00 31.48  ? 643 PRO A O   1 
ATOM   3335  C CB  . PRO A 1 441 ? -25.105 -16.895 59.902 1.00 30.43  ? 643 PRO A CB  1 
ATOM   3336  C CG  . PRO A 1 441 ? -24.016 -16.304 59.107 1.00 30.25  ? 643 PRO A CG  1 
ATOM   3337  C CD  . PRO A 1 441 ? -23.649 -15.030 59.800 1.00 30.21  ? 643 PRO A CD  1 
ATOM   3338  N N   . PRO A 1 442 ? -24.385 -18.851 62.159 1.00 34.51  ? 644 PRO A N   1 
ATOM   3339  C CA  . PRO A 1 442 ? -23.531 -19.965 62.571 1.00 34.00  ? 644 PRO A CA  1 
ATOM   3340  C C   . PRO A 1 442 ? -22.387 -20.157 61.595 1.00 34.29  ? 644 PRO A C   1 
ATOM   3341  O O   . PRO A 1 442 ? -22.594 -20.156 60.372 1.00 34.02  ? 644 PRO A O   1 
ATOM   3342  C CB  . PRO A 1 442 ? -24.488 -21.164 62.560 1.00 33.04  ? 644 PRO A CB  1 
ATOM   3343  C CG  . PRO A 1 442 ? -25.802 -20.566 62.858 1.00 33.39  ? 644 PRO A CG  1 
ATOM   3344  C CD  . PRO A 1 442 ? -25.812 -19.222 62.199 1.00 33.12  ? 644 PRO A CD  1 
ATOM   3345  N N   . PRO A 1 443 ? -21.165 -20.312 62.094 1.00 31.05  ? 645 PRO A N   1 
ATOM   3346  C CA  . PRO A 1 443 ? -19.999 -20.315 61.208 1.00 31.10  ? 645 PRO A CA  1 
ATOM   3347  C C   . PRO A 1 443 ? -19.925 -21.572 60.359 1.00 31.59  ? 645 PRO A C   1 
ATOM   3348  O O   . PRO A 1 443 ? -20.436 -22.635 60.716 1.00 31.52  ? 645 PRO A O   1 
ATOM   3349  C CB  . PRO A 1 443 ? -18.821 -20.242 62.182 1.00 31.41  ? 645 PRO A CB  1 
ATOM   3350  C CG  . PRO A 1 443 ? -19.341 -20.873 63.426 1.00 31.29  ? 645 PRO A CG  1 
ATOM   3351  C CD  . PRO A 1 443 ? -20.788 -20.483 63.507 1.00 31.75  ? 645 PRO A CD  1 
ATOM   3352  N N   . GLN A 1 444 ? -19.270 -21.431 59.210 1.00 28.80  ? 646 GLN A N   1 
ATOM   3353  C CA  . GLN A 1 444 ? -18.995 -22.582 58.365 1.00 29.86  ? 646 GLN A CA  1 
ATOM   3354  C C   . GLN A 1 444 ? -18.023 -23.526 59.054 1.00 29.63  ? 646 GLN A C   1 
ATOM   3355  O O   . GLN A 1 444 ? -17.068 -23.095 59.702 1.00 29.75  ? 646 GLN A O   1 
ATOM   3356  C CB  . GLN A 1 444 ? -18.414 -22.145 57.026 1.00 23.26  ? 646 GLN A CB  1 
ATOM   3357  C CG  . GLN A 1 444 ? -19.388 -21.455 56.111 1.00 28.06  ? 646 GLN A CG  1 
ATOM   3358  C CD  . GLN A 1 444 ? -18.739 -21.027 54.818 1.00 29.39  ? 646 GLN A CD  1 
ATOM   3359  O OE1 . GLN A 1 444 ? -17.545 -20.740 54.771 1.00 30.44  ? 646 GLN A OE1 1 
ATOM   3360  N NE2 . GLN A 1 444 ? -19.515 -21.019 53.751 1.00 29.50  ? 646 GLN A NE2 1 
ATOM   3361  N N   . ILE A 1 445 ? -18.268 -24.821 58.904 1.00 30.48  ? 647 ILE A N   1 
ATOM   3362  C CA  . ILE A 1 445 ? -17.421 -25.860 59.471 1.00 28.56  ? 647 ILE A CA  1 
ATOM   3363  C C   . ILE A 1 445 ? -16.783 -26.594 58.302 1.00 28.62  ? 647 ILE A C   1 
ATOM   3364  O O   . ILE A 1 445 ? -17.469 -27.314 57.568 1.00 29.75  ? 647 ILE A O   1 
ATOM   3365  C CB  . ILE A 1 445 ? -18.216 -26.823 60.357 1.00 33.41  ? 647 ILE A CB  1 
ATOM   3366  C CG1 . ILE A 1 445 ? -18.863 -26.061 61.507 1.00 32.36  ? 647 ILE A CG1 1 
ATOM   3367  C CG2 . ILE A 1 445 ? -17.309 -27.894 60.914 1.00 31.14  ? 647 ILE A CG2 1 
ATOM   3368  C CD1 . ILE A 1 445 ? -19.894 -26.861 62.233 1.00 31.92  ? 647 ILE A CD1 1 
ATOM   3369  N N   . LEU A 1 446 ? -15.479 -26.417 58.126 1.00 28.39  ? 648 LEU A N   1 
ATOM   3370  C CA  . LEU A 1 446 ? -14.756 -26.981 56.999 1.00 27.86  ? 648 LEU A CA  1 
ATOM   3371  C C   . LEU A 1 446 ? -13.931 -28.175 57.456 1.00 27.80  ? 648 LEU A C   1 
ATOM   3372  O O   . LEU A 1 446 ? -13.317 -28.150 58.525 1.00 29.73  ? 648 LEU A O   1 
ATOM   3373  C CB  . LEU A 1 446 ? -13.846 -25.935 56.351 1.00 24.58  ? 648 LEU A CB  1 
ATOM   3374  C CG  . LEU A 1 446 ? -14.465 -24.992 55.319 1.00 24.43  ? 648 LEU A CG  1 
ATOM   3375  C CD1 . LEU A 1 446 ? -15.088 -25.798 54.201 1.00 24.89  ? 648 LEU A CD1 1 
ATOM   3376  C CD2 . LEU A 1 446 ? -15.487 -24.064 55.938 1.00 24.32  ? 648 LEU A CD2 1 
ATOM   3377  N N   . ILE A 1 447 ? -13.918 -29.225 56.639 1.00 30.13  ? 649 ILE A N   1 
ATOM   3378  C CA  . ILE A 1 447 ? -13.269 -30.475 57.017 1.00 29.77  ? 649 ILE A CA  1 
ATOM   3379  C C   . ILE A 1 447 ? -12.715 -31.151 55.767 1.00 30.34  ? 649 ILE A C   1 
ATOM   3380  O O   . ILE A 1 447 ? -13.339 -31.129 54.703 1.00 31.03  ? 649 ILE A O   1 
ATOM   3381  C CB  . ILE A 1 447 ? -14.254 -31.387 57.784 1.00 31.43  ? 649 ILE A CB  1 
ATOM   3382  C CG1 . ILE A 1 447 ? -13.557 -32.651 58.283 1.00 31.02  ? 649 ILE A CG1 1 
ATOM   3383  C CG2 . ILE A 1 447 ? -15.467 -31.718 56.932 1.00 30.75  ? 649 ILE A CG2 1 
ATOM   3384  C CD1 . ILE A 1 447 ? -14.389 -33.458 59.247 1.00 31.19  ? 649 ILE A CD1 1 
ATOM   3385  N N   . LYS A 1 448 ? -11.530 -31.742 55.900 1.00 29.09  ? 650 LYS A N   1 
ATOM   3386  C CA  . LYS A 1 448 ? -10.926 -32.516 54.822 1.00 30.37  ? 650 LYS A CA  1 
ATOM   3387  C C   . LYS A 1 448 ? -10.037 -33.587 55.430 1.00 31.65  ? 650 LYS A C   1 
ATOM   3388  O O   . LYS A 1 448 ? -9.687  -33.534 56.611 1.00 31.32  ? 650 LYS A O   1 
ATOM   3389  C CB  . LYS A 1 448 ? -10.087 -31.656 53.879 1.00 28.74  ? 650 LYS A CB  1 
ATOM   3390  C CG  . LYS A 1 448 ? -8.857  -31.098 54.553 1.00 30.57  ? 650 LYS A CG  1 
ATOM   3391  C CD  . LYS A 1 448 ? -7.935  -30.400 53.579 1.00 31.91  ? 650 LYS A CD  1 
ATOM   3392  C CE  . LYS A 1 448 ? -7.289  -31.386 52.630 1.00 36.02  ? 650 LYS A CE  1 
ATOM   3393  N NZ  . LYS A 1 448 ? -6.348  -30.706 51.704 1.00 35.13  ? 650 LYS A NZ  1 
ATOM   3394  N N   . ASN A 1 449 ? -9.670  -34.558 54.600 1.00 32.14  ? 651 ASN A N   1 
ATOM   3395  C CA  . ASN A 1 449 ? -8.687  -35.559 54.988 1.00 33.22  ? 651 ASN A CA  1 
ATOM   3396  C C   . ASN A 1 449 ? -7.291  -35.067 54.642 1.00 34.08  ? 651 ASN A C   1 
ATOM   3397  O O   . ASN A 1 449 ? -7.052  -34.585 53.531 1.00 34.98  ? 651 ASN A O   1 
ATOM   3398  C CB  . ASN A 1 449 ? -8.959  -36.886 54.284 1.00 33.20  ? 651 ASN A CB  1 
ATOM   3399  C CG  . ASN A 1 449 ? -10.265 -37.511 54.706 1.00 36.28  ? 651 ASN A CG  1 
ATOM   3400  O OD1 . ASN A 1 449 ? -11.082 -37.893 53.871 1.00 37.66  ? 651 ASN A OD1 1 
ATOM   3401  N ND2 . ASN A 1 449 ? -10.466 -37.629 56.009 1.00 38.34  ? 651 ASN A ND2 1 
ATOM   3402  N N   . THR A 1 450 ? -6.374  -35.186 55.589 1.00 35.79  ? 652 THR A N   1 
ATOM   3403  C CA  . THR A 1 450 ? -4.994  -34.805 55.328 1.00 37.14  ? 652 THR A CA  1 
ATOM   3404  C C   . THR A 1 450 ? -4.403  -35.748 54.287 1.00 35.68  ? 652 THR A C   1 
ATOM   3405  O O   . THR A 1 450 ? -4.474  -36.969 54.458 1.00 34.50  ? 652 THR A O   1 
ATOM   3406  C CB  . THR A 1 450 ? -4.165  -34.854 56.606 1.00 31.75  ? 652 THR A CB  1 
ATOM   3407  O OG1 . THR A 1 450 ? -4.757  -34.001 57.590 1.00 39.31  ? 652 THR A OG1 1 
ATOM   3408  C CG2 . THR A 1 450 ? -2.755  -34.372 56.332 1.00 31.54  ? 652 THR A CG2 1 
ATOM   3409  N N   . PRO A 1 451 ? -3.831  -35.233 53.201 1.00 36.85  ? 653 PRO A N   1 
ATOM   3410  C CA  . PRO A 1 451 ? -3.261  -36.124 52.189 1.00 36.60  ? 653 PRO A CA  1 
ATOM   3411  C C   . PRO A 1 451 ? -2.075  -36.891 52.743 1.00 36.94  ? 653 PRO A C   1 
ATOM   3412  O O   . PRO A 1 451 ? -1.180  -36.322 53.371 1.00 37.20  ? 653 PRO A O   1 
ATOM   3413  C CB  . PRO A 1 451 ? -2.839  -35.165 51.072 1.00 33.14  ? 653 PRO A CB  1 
ATOM   3414  C CG  . PRO A 1 451 ? -2.620  -33.875 51.759 1.00 32.18  ? 653 PRO A CG  1 
ATOM   3415  C CD  . PRO A 1 451 ? -3.648  -33.817 52.845 1.00 32.90  ? 653 PRO A CD  1 
ATOM   3416  N N   . VAL A 1 452 ? -2.083  -38.198 52.512 1.00 42.94  ? 654 VAL A N   1 
ATOM   3417  C CA  . VAL A 1 452 ? -0.979  -39.060 52.919 1.00 42.93  ? 654 VAL A CA  1 
ATOM   3418  C C   . VAL A 1 452 ? -0.248  -39.496 51.658 1.00 43.04  ? 654 VAL A C   1 
ATOM   3419  O O   . VAL A 1 452 ? -0.787  -40.293 50.876 1.00 43.44  ? 654 VAL A O   1 
ATOM   3420  C CB  . VAL A 1 452 ? -1.474  -40.266 53.730 1.00 45.53  ? 654 VAL A CB  1 
ATOM   3421  C CG1 . VAL A 1 452 ? -0.320  -41.196 54.041 1.00 45.08  ? 654 VAL A CG1 1 
ATOM   3422  C CG2 . VAL A 1 452 ? -2.144  -39.802 55.007 1.00 43.88  ? 654 VAL A CG2 1 
ATOM   3423  N N   . PRO A 1 453 ? 0.962   -39.005 51.416 1.00 45.93  ? 655 PRO A N   1 
ATOM   3424  C CA  . PRO A 1 453 ? 1.648   -39.338 50.168 1.00 46.50  ? 655 PRO A CA  1 
ATOM   3425  C C   . PRO A 1 453 ? 2.014   -40.809 50.094 1.00 48.03  ? 655 PRO A C   1 
ATOM   3426  O O   . PRO A 1 453 ? 2.227   -41.478 51.107 1.00 47.44  ? 655 PRO A O   1 
ATOM   3427  C CB  . PRO A 1 453 ? 2.900   -38.455 50.210 1.00 42.38  ? 655 PRO A CB  1 
ATOM   3428  C CG  . PRO A 1 453 ? 3.133   -38.211 51.656 1.00 42.66  ? 655 PRO A CG  1 
ATOM   3429  C CD  . PRO A 1 453 ? 1.771   -38.121 52.270 1.00 42.25  ? 655 PRO A CD  1 
ATOM   3430  N N   . ALA A 1 454 ? 2.074   -41.310 48.865 1.00 46.08  ? 656 ALA A N   1 
ATOM   3431  C CA  . ALA A 1 454 ? 2.612   -42.634 48.616 1.00 48.19  ? 656 ALA A CA  1 
ATOM   3432  C C   . ALA A 1 454 ? 4.135   -42.578 48.674 1.00 51.06  ? 656 ALA A C   1 
ATOM   3433  O O   . ALA A 1 454 ? 4.733   -41.577 49.077 1.00 52.02  ? 656 ALA A O   1 
ATOM   3434  C CB  . ALA A 1 454 ? 2.123   -43.166 47.271 1.00 50.30  ? 656 ALA A CB  1 
ATOM   3435  N N   . ASP A 1 455 ? 4.772   -43.669 48.279 1.00 52.57  ? 657 ASP A N   1 
ATOM   3436  C CA  . ASP A 1 455 ? 6.225   -43.737 48.351 1.00 53.90  ? 657 ASP A CA  1 
ATOM   3437  C C   . ASP A 1 455 ? 6.862   -42.742 47.385 1.00 52.20  ? 657 ASP A C   1 
ATOM   3438  O O   . ASP A 1 455 ? 6.588   -42.787 46.180 1.00 51.75  ? 657 ASP A O   1 
ATOM   3439  C CB  . ASP A 1 455 ? 6.709   -45.159 48.071 1.00 57.18  ? 657 ASP A CB  1 
ATOM   3440  C CG  . ASP A 1 455 ? 6.163   -45.723 46.778 1.00 61.43  ? 657 ASP A CG  1 
ATOM   3441  O OD1 . ASP A 1 455 ? 5.249   -45.112 46.188 1.00 63.66  ? 657 ASP A OD1 1 
ATOM   3442  O OD2 . ASP A 1 455 ? 6.656   -46.783 46.346 1.00 63.36  ? 657 ASP A OD2 1 
ATOM   3443  N N   . PRO A 1 456 ? 7.687   -41.821 47.871 1.00 46.59  ? 658 PRO A N   1 
ATOM   3444  C CA  . PRO A 1 456 ? 8.398   -40.914 46.976 1.00 46.27  ? 658 PRO A CA  1 
ATOM   3445  C C   . PRO A 1 456 ? 9.551   -41.627 46.296 1.00 46.78  ? 658 PRO A C   1 
ATOM   3446  O O   . PRO A 1 456 ? 9.999   -42.684 46.765 1.00 47.09  ? 658 PRO A O   1 
ATOM   3447  C CB  . PRO A 1 456 ? 8.902   -39.815 47.922 1.00 44.02  ? 658 PRO A CB  1 
ATOM   3448  C CG  . PRO A 1 456 ? 9.052   -40.503 49.222 1.00 44.01  ? 658 PRO A CG  1 
ATOM   3449  C CD  . PRO A 1 456 ? 7.962   -41.530 49.288 1.00 44.61  ? 658 PRO A CD  1 
ATOM   3450  N N   . PRO A 1 457 ? 10.056  -41.091 45.188 1.00 45.88  ? 659 PRO A N   1 
ATOM   3451  C CA  . PRO A 1 457 ? 11.236  -41.686 44.554 1.00 46.60  ? 659 PRO A CA  1 
ATOM   3452  C C   . PRO A 1 457 ? 12.471  -41.510 45.426 1.00 47.16  ? 659 PRO A C   1 
ATOM   3453  O O   . PRO A 1 457 ? 12.513  -40.692 46.344 1.00 47.77  ? 659 PRO A O   1 
ATOM   3454  C CB  . PRO A 1 457 ? 11.355  -40.917 43.237 1.00 44.75  ? 659 PRO A CB  1 
ATOM   3455  C CG  . PRO A 1 457 ? 10.695  -39.614 43.510 1.00 44.07  ? 659 PRO A CG  1 
ATOM   3456  C CD  . PRO A 1 457 ? 9.564   -39.919 44.444 1.00 43.90  ? 659 PRO A CD  1 
ATOM   3457  N N   . THR A 1 458 ? 13.490  -42.314 45.137 1.00 46.46  ? 660 THR A N   1 
ATOM   3458  C CA  . THR A 1 458 ? 14.724  -42.265 45.909 1.00 46.40  ? 660 THR A CA  1 
ATOM   3459  C C   . THR A 1 458 ? 15.668  -41.159 45.460 1.00 45.09  ? 660 THR A C   1 
ATOM   3460  O O   . THR A 1 458 ? 16.571  -40.793 46.219 1.00 45.13  ? 660 THR A O   1 
ATOM   3461  C CB  . THR A 1 458 ? 15.447  -43.612 45.838 1.00 46.69  ? 660 THR A CB  1 
ATOM   3462  O OG1 . THR A 1 458 ? 15.730  -43.934 44.472 1.00 47.98  ? 660 THR A OG1 1 
ATOM   3463  C CG2 . THR A 1 458 ? 14.583  -44.701 46.442 1.00 45.31  ? 660 THR A CG2 1 
ATOM   3464  N N   . ALA A 1 459 ? 15.485  -40.621 44.259 1.00 44.08  ? 661 ALA A N   1 
ATOM   3465  C CA  . ALA A 1 459 ? 16.251  -39.484 43.774 1.00 42.99  ? 661 ALA A CA  1 
ATOM   3466  C C   . ALA A 1 459 ? 15.381  -38.238 43.833 1.00 43.06  ? 661 ALA A C   1 
ATOM   3467  O O   . ALA A 1 459 ? 14.203  -38.277 43.466 1.00 44.07  ? 661 ALA A O   1 
ATOM   3468  C CB  . ALA A 1 459 ? 16.748  -39.715 42.346 1.00 39.49  ? 661 ALA A CB  1 
ATOM   3469  N N   . PHE A 1 460 ? 15.964  -37.137 44.299 1.00 38.11  ? 662 PHE A N   1 
ATOM   3470  C CA  . PHE A 1 460 ? 15.185  -35.933 44.553 1.00 37.81  ? 662 PHE A CA  1 
ATOM   3471  C C   . PHE A 1 460 ? 14.581  -35.374 43.272 1.00 38.11  ? 662 PHE A C   1 
ATOM   3472  O O   . PHE A 1 460 ? 15.212  -35.366 42.213 1.00 38.14  ? 662 PHE A O   1 
ATOM   3473  C CB  . PHE A 1 460 ? 16.051  -34.868 45.220 1.00 35.38  ? 662 PHE A CB  1 
ATOM   3474  C CG  . PHE A 1 460 ? 15.345  -33.564 45.411 1.00 35.47  ? 662 PHE A CG  1 
ATOM   3475  C CD1 . PHE A 1 460 ? 14.469  -33.388 46.463 1.00 35.01  ? 662 PHE A CD1 1 
ATOM   3476  C CD2 . PHE A 1 460 ? 15.541  -32.517 44.528 1.00 34.72  ? 662 PHE A CD2 1 
ATOM   3477  C CE1 . PHE A 1 460 ? 13.811  -32.193 46.638 1.00 34.52  ? 662 PHE A CE1 1 
ATOM   3478  C CE2 . PHE A 1 460 ? 14.881  -31.321 44.698 1.00 34.82  ? 662 PHE A CE2 1 
ATOM   3479  C CZ  . PHE A 1 460 ? 14.016  -31.159 45.754 1.00 35.00  ? 662 PHE A CZ  1 
ATOM   3480  N N   . ASN A 1 461 ? 13.343  -34.902 43.383 1.00 38.51  ? 663 ASN A N   1 
ATOM   3481  C CA  . ASN A 1 461 ? 12.666  -34.176 42.322 1.00 39.78  ? 663 ASN A CA  1 
ATOM   3482  C C   . ASN A 1 461 ? 11.853  -33.058 42.952 1.00 39.94  ? 663 ASN A C   1 
ATOM   3483  O O   . ASN A 1 461 ? 11.151  -33.278 43.942 1.00 39.58  ? 663 ASN A O   1 
ATOM   3484  C CB  . ASN A 1 461 ? 11.756  -35.091 41.499 1.00 41.62  ? 663 ASN A CB  1 
ATOM   3485  C CG  . ASN A 1 461 ? 11.215  -34.410 40.264 1.00 43.78  ? 663 ASN A CG  1 
ATOM   3486  O OD1 . ASN A 1 461 ? 11.857  -33.528 39.699 1.00 45.37  ? 663 ASN A OD1 1 
ATOM   3487  N ND2 . ASN A 1 461 ? 10.029  -34.817 39.834 1.00 45.83  ? 663 ASN A ND2 1 
ATOM   3488  N N   . LYS A 1 462 ? 11.945  -31.862 42.373 1.00 40.41  ? 664 LYS A N   1 
ATOM   3489  C CA  . LYS A 1 462 ? 11.342  -30.677 42.968 1.00 41.42  ? 664 LYS A CA  1 
ATOM   3490  C C   . LYS A 1 462 ? 9.839   -30.591 42.760 1.00 41.13  ? 664 LYS A C   1 
ATOM   3491  O O   . LYS A 1 462 ? 9.188   -29.774 43.419 1.00 39.72  ? 664 LYS A O   1 
ATOM   3492  C CB  . LYS A 1 462 ? 11.987  -29.412 42.405 1.00 36.88  ? 664 LYS A CB  1 
ATOM   3493  C CG  . LYS A 1 462 ? 11.739  -29.199 40.930 1.00 41.70  ? 664 LYS A CG  1 
ATOM   3494  C CD  . LYS A 1 462 ? 12.548  -28.037 40.400 1.00 47.37  ? 664 LYS A CD  1 
ATOM   3495  C CE  . LYS A 1 462 ? 12.228  -27.771 38.947 1.00 48.89  ? 664 LYS A CE  1 
ATOM   3496  N NZ  . LYS A 1 462 ? 10.871  -27.194 38.796 1.00 49.68  ? 664 LYS A NZ  1 
ATOM   3497  N N   . ASP A 1 463 ? 9.275   -31.398 41.868 1.00 43.59  ? 665 ASP A N   1 
ATOM   3498  C CA  . ASP A 1 463 ? 7.846   -31.337 41.607 1.00 44.93  ? 665 ASP A CA  1 
ATOM   3499  C C   . ASP A 1 463 ? 7.056   -31.827 42.813 1.00 43.07  ? 665 ASP A C   1 
ATOM   3500  O O   . ASP A 1 463 ? 7.488   -32.719 43.547 1.00 43.78  ? 665 ASP A O   1 
ATOM   3501  C CB  . ASP A 1 463 ? 7.499   -32.172 40.378 1.00 45.89  ? 665 ASP A CB  1 
ATOM   3502  C CG  . ASP A 1 463 ? 8.045   -31.575 39.101 1.00 51.94  ? 665 ASP A CG  1 
ATOM   3503  O OD1 . ASP A 1 463 ? 8.419   -30.384 39.115 1.00 54.66  ? 665 ASP A OD1 1 
ATOM   3504  O OD2 . ASP A 1 463 ? 8.106   -32.297 38.085 1.00 55.42  ? 665 ASP A OD2 1 
ATOM   3505  N N   . LYS A 1 464 ? 5.882   -31.234 43.014 1.00 41.61  ? 666 LYS A N   1 
ATOM   3506  C CA  . LYS A 1 464 ? 5.030   -31.642 44.120 1.00 40.11  ? 666 LYS A CA  1 
ATOM   3507  C C   . LYS A 1 464 ? 4.554   -33.074 43.913 1.00 40.63  ? 666 LYS A C   1 
ATOM   3508  O O   . LYS A 1 464 ? 4.507   -33.582 42.791 1.00 40.91  ? 666 LYS A O   1 
ATOM   3509  C CB  . LYS A 1 464 ? 3.833   -30.704 44.261 1.00 33.18  ? 666 LYS A CB  1 
ATOM   3510  C CG  . LYS A 1 464 ? 2.891   -30.704 43.075 1.00 30.94  ? 666 LYS A CG  1 
ATOM   3511  C CD  . LYS A 1 464 ? 1.727   -29.765 43.316 1.00 30.54  ? 666 LYS A CD  1 
ATOM   3512  C CE  . LYS A 1 464 ? 0.791   -29.728 42.126 1.00 30.12  ? 666 LYS A CE  1 
ATOM   3513  N NZ  . LYS A 1 464 ? -0.351  -28.810 42.365 1.00 28.91  ? 666 LYS A NZ  1 
ATOM   3514  N N   . LEU A 1 465 ? 4.201   -33.727 45.013 1.00 39.14  ? 667 LEU A N   1 
ATOM   3515  C CA  . LEU A 1 465 ? 3.851   -35.139 44.971 1.00 39.33  ? 667 LEU A CA  1 
ATOM   3516  C C   . LEU A 1 465 ? 2.419   -35.297 44.479 1.00 39.88  ? 667 LEU A C   1 
ATOM   3517  O O   . LEU A 1 465 ? 1.485   -34.784 45.102 1.00 39.97  ? 667 LEU A O   1 
ATOM   3518  C CB  . LEU A 1 465 ? 4.028   -35.757 46.352 1.00 35.43  ? 667 LEU A CB  1 
ATOM   3519  C CG  . LEU A 1 465 ? 5.463   -35.689 46.875 1.00 34.78  ? 667 LEU A CG  1 
ATOM   3520  C CD1 . LEU A 1 465 ? 5.543   -36.221 48.288 1.00 35.57  ? 667 LEU A CD1 1 
ATOM   3521  C CD2 . LEU A 1 465 ? 6.411   -36.442 45.957 1.00 34.36  ? 667 LEU A CD2 1 
ATOM   3522  N N   . ASN A 1 466 ? 2.246   -35.991 43.354 1.00 42.66  ? 668 ASN A N   1 
ATOM   3523  C CA  . ASN A 1 466 ? 0.928   -36.262 42.797 1.00 44.14  ? 668 ASN A CA  1 
ATOM   3524  C C   . ASN A 1 466 ? 0.397   -37.649 43.139 1.00 43.25  ? 668 ASN A C   1 
ATOM   3525  O O   . ASN A 1 466 ? -0.718  -37.985 42.733 1.00 43.90  ? 668 ASN A O   1 
ATOM   3526  C CB  . ASN A 1 466 ? 0.944   -36.062 41.275 1.00 41.40  ? 668 ASN A CB  1 
ATOM   3527  C CG  . ASN A 1 466 ? 1.954   -36.949 40.568 1.00 46.76  ? 668 ASN A CG  1 
ATOM   3528  O OD1 . ASN A 1 466 ? 2.227   -38.073 40.987 1.00 50.30  ? 668 ASN A OD1 1 
ATOM   3529  N ND2 . ASN A 1 466 ? 2.514   -36.440 39.478 1.00 50.10  ? 668 ASN A ND2 1 
ATOM   3530  N N   . SER A 1 467 ? 1.162   -38.460 43.863 1.00 45.69  ? 669 SER A N   1 
ATOM   3531  C CA  . SER A 1 467 ? 0.782   -39.828 44.189 1.00 43.88  ? 669 SER A CA  1 
ATOM   3532  C C   . SER A 1 467 ? 0.414   -39.914 45.662 1.00 42.65  ? 669 SER A C   1 
ATOM   3533  O O   . SER A 1 467 ? 1.260   -39.681 46.530 1.00 41.51  ? 669 SER A O   1 
ATOM   3534  C CB  . SER A 1 467 ? 1.919   -40.801 43.868 1.00 46.33  ? 669 SER A CB  1 
ATOM   3535  O OG  . SER A 1 467 ? 1.578   -42.127 44.224 1.00 48.53  ? 669 SER A OG  1 
ATOM   3536  N N   . PHE A 1 468 ? -0.840  -40.256 45.940 1.00 47.45  ? 670 PHE A N   1 
ATOM   3537  C CA  . PHE A 1 468 ? -1.337  -40.324 47.305 1.00 46.35  ? 670 PHE A CA  1 
ATOM   3538  C C   . PHE A 1 468 ? -2.002  -41.668 47.556 1.00 46.07  ? 670 PHE A C   1 
ATOM   3539  O O   . PHE A 1 468 ? -2.336  -42.408 46.628 1.00 47.27  ? 670 PHE A O   1 
ATOM   3540  C CB  . PHE A 1 468 ? -2.328  -39.190 47.603 1.00 39.66  ? 670 PHE A CB  1 
ATOM   3541  C CG  . PHE A 1 468 ? -1.726  -37.822 47.503 1.00 40.68  ? 670 PHE A CG  1 
ATOM   3542  C CD1 . PHE A 1 468 ? -0.986  -37.297 48.549 1.00 41.62  ? 670 PHE A CD1 1 
ATOM   3543  C CD2 . PHE A 1 468 ? -1.901  -37.059 46.363 1.00 40.28  ? 670 PHE A CD2 1 
ATOM   3544  C CE1 . PHE A 1 468 ? -0.428  -36.042 48.456 1.00 42.98  ? 670 PHE A CE1 1 
ATOM   3545  C CE2 . PHE A 1 468 ? -1.348  -35.804 46.267 1.00 41.42  ? 670 PHE A CE2 1 
ATOM   3546  C CZ  . PHE A 1 468 ? -0.612  -35.294 47.314 1.00 42.16  ? 670 PHE A CZ  1 
ATOM   3547  N N   . ILE A 1 469 ? -2.186  -41.972 48.835 1.00 48.67  ? 671 ILE A N   1 
ATOM   3548  C CA  . ILE A 1 469 ? -2.904  -43.171 49.246 1.00 48.19  ? 671 ILE A CA  1 
ATOM   3549  C C   . ILE A 1 469 ? -4.396  -42.881 49.232 1.00 48.24  ? 671 ILE A C   1 
ATOM   3550  O O   . ILE A 1 469 ? -4.858  -41.920 49.859 1.00 48.42  ? 671 ILE A O   1 
ATOM   3551  C CB  . ILE A 1 469 ? -2.442  -43.628 50.638 1.00 50.02  ? 671 ILE A CB  1 
ATOM   3552  C CG1 . ILE A 1 469 ? -1.003  -44.140 50.583 1.00 49.74  ? 671 ILE A CG1 1 
ATOM   3553  C CG2 . ILE A 1 469 ? -3.377  -44.686 51.195 1.00 49.44  ? 671 ILE A CG2 1 
ATOM   3554  C CD1 . ILE A 1 469 ? -0.400  -44.388 51.940 1.00 53.40  ? 671 ILE A CD1 1 
ATOM   3555  N N   . THR A 1 470 ? -5.155  -43.708 48.514 1.00 51.44  ? 672 THR A N   1 
ATOM   3556  C CA  . THR A 1 470 ? -6.606  -43.572 48.494 1.00 52.50  ? 672 THR A CA  1 
ATOM   3557  C C   . THR A 1 470 ? -7.155  -43.724 49.906 1.00 51.41  ? 672 THR A C   1 
ATOM   3558  O O   . THR A 1 470 ? -6.834  -44.686 50.610 1.00 50.19  ? 672 THR A O   1 
ATOM   3559  C CB  . THR A 1 470 ? -7.226  -44.612 47.566 1.00 53.42  ? 672 THR A CB  1 
ATOM   3560  O OG1 . THR A 1 470 ? -6.725  -44.425 46.237 1.00 58.08  ? 672 THR A OG1 1 
ATOM   3561  C CG2 . THR A 1 470 ? -8.737  -44.473 47.550 1.00 53.79  ? 672 THR A CG2 1 
ATOM   3562  N N   . GLN A 1 471 ? -7.978  -42.768 50.323 1.00 46.52  ? 673 GLN A N   1 
ATOM   3563  C CA  . GLN A 1 471 ? -8.276  -42.620 51.737 1.00 45.78  ? 673 GLN A CA  1 
ATOM   3564  C C   . GLN A 1 471 ? -9.647  -41.984 51.908 1.00 44.95  ? 673 GLN A C   1 
ATOM   3565  O O   . GLN A 1 471 ? -10.083 -41.189 51.072 1.00 46.80  ? 673 GLN A O   1 
ATOM   3566  C CB  . GLN A 1 471 ? -7.188  -41.775 52.405 1.00 46.55  ? 673 GLN A CB  1 
ATOM   3567  C CG  . GLN A 1 471 ? -7.277  -41.625 53.899 1.00 50.87  ? 673 GLN A CG  1 
ATOM   3568  C CD  . GLN A 1 471 ? -6.060  -40.913 54.452 1.00 54.19  ? 673 GLN A CD  1 
ATOM   3569  O OE1 . GLN A 1 471 ? -5.105  -40.650 53.725 1.00 56.71  ? 673 GLN A OE1 1 
ATOM   3570  N NE2 . GLN A 1 471 ? -6.092  -40.586 55.733 1.00 53.69  ? 673 GLN A NE2 1 
ATOM   3571  N N   . TYR A 1 472 ? -10.325 -42.355 52.991 1.00 47.39  ? 674 TYR A N   1 
ATOM   3572  C CA  . TYR A 1 472 ? -11.532 -41.658 53.407 1.00 46.09  ? 674 TYR A CA  1 
ATOM   3573  C C   . TYR A 1 472 ? -11.694 -41.851 54.905 1.00 45.07  ? 674 TYR A C   1 
ATOM   3574  O O   . TYR A 1 472 ? -11.095 -42.746 55.502 1.00 44.85  ? 674 TYR A O   1 
ATOM   3575  C CB  . TYR A 1 472 ? -12.779 -42.147 52.656 1.00 47.14  ? 674 TYR A CB  1 
ATOM   3576  C CG  . TYR A 1 472 ? -13.211 -43.559 52.983 1.00 47.34  ? 674 TYR A CG  1 
ATOM   3577  C CD1 . TYR A 1 472 ? -14.114 -43.808 54.007 1.00 47.61  ? 674 TYR A CD1 1 
ATOM   3578  C CD2 . TYR A 1 472 ? -12.728 -44.641 52.263 1.00 47.95  ? 674 TYR A CD2 1 
ATOM   3579  C CE1 . TYR A 1 472 ? -14.515 -45.089 54.309 1.00 48.53  ? 674 TYR A CE1 1 
ATOM   3580  C CE2 . TYR A 1 472 ? -13.125 -45.927 52.560 1.00 48.56  ? 674 TYR A CE2 1 
ATOM   3581  C CZ  . TYR A 1 472 ? -14.018 -46.144 53.583 1.00 49.38  ? 674 TYR A CZ  1 
ATOM   3582  O OH  . TYR A 1 472 ? -14.418 -47.423 53.882 1.00 49.55  ? 674 TYR A OH  1 
ATOM   3583  N N   . SER A 1 473 ? -12.509 -40.997 55.512 1.00 45.38  ? 675 SER A N   1 
ATOM   3584  C CA  . SER A 1 473 ? -12.739 -41.046 56.946 1.00 45.30  ? 675 SER A CA  1 
ATOM   3585  C C   . SER A 1 473 ? -14.233 -41.038 57.228 1.00 45.06  ? 675 SER A C   1 
ATOM   3586  O O   . SER A 1 473 ? -15.045 -40.590 56.414 1.00 45.28  ? 675 SER A O   1 
ATOM   3587  C CB  . SER A 1 473 ? -12.050 -39.881 57.665 1.00 43.26  ? 675 SER A CB  1 
ATOM   3588  O OG  . SER A 1 473 ? -12.574 -38.640 57.237 1.00 46.70  ? 675 SER A OG  1 
ATOM   3589  N N   . THR A 1 474 ? -14.589 -41.554 58.399 1.00 46.24  ? 676 THR A N   1 
ATOM   3590  C CA  . THR A 1 474 ? -15.975 -41.615 58.827 1.00 46.62  ? 676 THR A CA  1 
ATOM   3591  C C   . THR A 1 474 ? -16.020 -41.395 60.329 1.00 45.20  ? 676 THR A C   1 
ATOM   3592  O O   . THR A 1 474 ? -15.018 -41.558 61.028 1.00 46.26  ? 676 THR A O   1 
ATOM   3593  C CB  . THR A 1 474 ? -16.622 -42.952 58.446 1.00 46.68  ? 676 THR A CB  1 
ATOM   3594  O OG1 . THR A 1 474 ? -18.025 -42.906 58.726 1.00 50.00  ? 676 THR A OG1 1 
ATOM   3595  C CG2 . THR A 1 474 ? -15.989 -44.090 59.225 1.00 46.24  ? 676 THR A CG2 1 
ATOM   3596  N N   . GLY A 1 475 ? -17.192 -41.019 60.823 1.00 45.94  ? 677 GLY A N   1 
ATOM   3597  C CA  . GLY A 1 475 ? -17.308 -40.670 62.223 1.00 44.27  ? 677 GLY A CA  1 
ATOM   3598  C C   . GLY A 1 475 ? -18.690 -40.168 62.566 1.00 44.29  ? 677 GLY A C   1 
ATOM   3599  O O   . GLY A 1 475 ? -19.663 -40.454 61.867 1.00 44.27  ? 677 GLY A O   1 
ATOM   3600  N N   . GLN A 1 476 ? -18.763 -39.418 63.660 1.00 46.83  ? 678 GLN A N   1 
ATOM   3601  C CA  . GLN A 1 476 ? -20.026 -38.970 64.224 1.00 47.38  ? 678 GLN A CA  1 
ATOM   3602  C C   . GLN A 1 476 ? -20.046 -37.453 64.347 1.00 48.21  ? 678 GLN A C   1 
ATOM   3603  O O   . GLN A 1 476 ? -19.014 -36.820 64.586 1.00 47.65  ? 678 GLN A O   1 
ATOM   3604  C CB  . GLN A 1 476 ? -20.254 -39.595 65.603 1.00 45.74  ? 678 GLN A CB  1 
ATOM   3605  C CG  . GLN A 1 476 ? -20.302 -41.108 65.604 1.00 47.81  ? 678 GLN A CG  1 
ATOM   3606  C CD  . GLN A 1 476 ? -21.412 -41.646 64.743 1.00 49.62  ? 678 GLN A CD  1 
ATOM   3607  O OE1 . GLN A 1 476 ? -22.516 -41.106 64.730 1.00 51.00  ? 678 GLN A OE1 1 
ATOM   3608  N NE2 . GLN A 1 476 ? -21.128 -42.713 64.010 1.00 49.30  ? 678 GLN A NE2 1 
ATOM   3609  N N   . VAL A 1 477 ? -21.236 -36.877 64.193 1.00 43.43  ? 679 VAL A N   1 
ATOM   3610  C CA  . VAL A 1 477 ? -21.473 -35.451 64.385 1.00 43.78  ? 679 VAL A CA  1 
ATOM   3611  C C   . VAL A 1 477 ? -22.742 -35.272 65.201 1.00 44.91  ? 679 VAL A C   1 
ATOM   3612  O O   . VAL A 1 477 ? -23.777 -35.869 64.889 1.00 44.95  ? 679 VAL A O   1 
ATOM   3613  C CB  . VAL A 1 477 ? -21.585 -34.696 63.046 1.00 40.09  ? 679 VAL A CB  1 
ATOM   3614  C CG1 . VAL A 1 477 ? -22.140 -33.308 63.268 1.00 41.50  ? 679 VAL A CG1 1 
ATOM   3615  C CG2 . VAL A 1 477 ? -20.233 -34.574 62.420 1.00 41.65  ? 679 VAL A CG2 1 
ATOM   3616  N N   . SER A 1 478 ? -22.662 -34.449 66.242 1.00 43.48  ? 680 SER A N   1 
ATOM   3617  C CA  . SER A 1 478 ? -23.824 -34.093 67.041 1.00 44.85  ? 680 SER A CA  1 
ATOM   3618  C C   . SER A 1 478 ? -23.911 -32.581 67.186 1.00 44.68  ? 680 SER A C   1 
ATOM   3619  O O   . SER A 1 478 ? -22.983 -31.940 67.687 1.00 45.41  ? 680 SER A O   1 
ATOM   3620  C CB  . SER A 1 478 ? -23.783 -34.744 68.425 1.00 44.66  ? 680 SER A CB  1 
ATOM   3621  O OG  . SER A 1 478 ? -22.717 -34.234 69.199 1.00 50.43  ? 680 SER A OG  1 
ATOM   3622  N N   . VAL A 1 479 ? -25.033 -32.019 66.745 1.00 46.73  ? 681 VAL A N   1 
ATOM   3623  C CA  . VAL A 1 479 ? -25.303 -30.591 66.853 1.00 46.63  ? 681 VAL A CA  1 
ATOM   3624  C C   . VAL A 1 479 ? -26.490 -30.389 67.785 1.00 47.17  ? 681 VAL A C   1 
ATOM   3625  O O   . VAL A 1 479 ? -27.487 -31.114 67.706 1.00 46.80  ? 681 VAL A O   1 
ATOM   3626  C CB  . VAL A 1 479 ? -25.556 -29.952 65.470 1.00 44.00  ? 681 VAL A CB  1 
ATOM   3627  C CG1 . VAL A 1 479 ? -26.709 -30.637 64.759 1.00 42.54  ? 681 VAL A CG1 1 
ATOM   3628  C CG2 . VAL A 1 479 ? -25.830 -28.471 65.618 1.00 46.30  ? 681 VAL A CG2 1 
ATOM   3629  N N   . GLU A 1 480 ? -26.369 -29.416 68.684 1.00 45.58  ? 682 GLU A N   1 
ATOM   3630  C CA  . GLU A 1 480 ? -27.374 -29.155 69.705 1.00 46.76  ? 682 GLU A CA  1 
ATOM   3631  C C   . GLU A 1 480 ? -27.737 -27.679 69.700 1.00 45.71  ? 682 GLU A C   1 
ATOM   3632  O O   . GLU A 1 480 ? -26.896 -26.832 70.013 1.00 46.82  ? 682 GLU A O   1 
ATOM   3633  C CB  . GLU A 1 480 ? -26.860 -29.568 71.085 1.00 49.31  ? 682 GLU A CB  1 
ATOM   3634  C CG  . GLU A 1 480 ? -27.851 -29.372 72.209 1.00 58.19  ? 682 GLU A CG  1 
ATOM   3635  C CD  . GLU A 1 480 ? -27.292 -29.813 73.545 1.00 64.71  ? 682 GLU A CD  1 
ATOM   3636  O OE1 . GLU A 1 480 ? -26.115 -30.230 73.586 1.00 68.26  ? 682 GLU A OE1 1 
ATOM   3637  O OE2 . GLU A 1 480 ? -28.023 -29.745 74.554 1.00 68.98  ? 682 GLU A OE2 1 
ATOM   3638  N N   . ILE A 1 481 ? -28.989 -27.374 69.365 1.00 49.15  ? 683 ILE A N   1 
ATOM   3639  C CA  . ILE A 1 481 ? -29.477 -26.001 69.304 1.00 47.55  ? 683 ILE A CA  1 
ATOM   3640  C C   . ILE A 1 481 ? -30.545 -25.816 70.371 1.00 49.04  ? 683 ILE A C   1 
ATOM   3641  O O   . ILE A 1 481 ? -31.421 -26.672 70.533 1.00 49.55  ? 683 ILE A O   1 
ATOM   3642  C CB  . ILE A 1 481 ? -30.045 -25.650 67.917 1.00 44.76  ? 683 ILE A CB  1 
ATOM   3643  C CG1 . ILE A 1 481 ? -28.962 -25.755 66.851 1.00 44.13  ? 683 ILE A CG1 1 
ATOM   3644  C CG2 . ILE A 1 481 ? -30.614 -24.244 67.913 1.00 42.17  ? 683 ILE A CG2 1 
ATOM   3645  C CD1 . ILE A 1 481 ? -29.491 -25.590 65.460 1.00 43.62  ? 683 ILE A CD1 1 
ATOM   3646  N N   . GLU A 1 482 ? -30.477 -24.699 71.088 1.00 48.58  ? 684 GLU A N   1 
ATOM   3647  C CA  . GLU A 1 482 ? -31.470 -24.338 72.089 1.00 50.06  ? 684 GLU A CA  1 
ATOM   3648  C C   . GLU A 1 482 ? -32.453 -23.335 71.496 1.00 48.91  ? 684 GLU A C   1 
ATOM   3649  O O   . GLU A 1 482 ? -32.059 -22.239 71.085 1.00 49.07  ? 684 GLU A O   1 
ATOM   3650  C CB  . GLU A 1 482 ? -30.794 -23.760 73.332 1.00 47.82  ? 684 GLU A CB  1 
ATOM   3651  C CG  . GLU A 1 482 ? -31.746 -23.405 74.454 1.00 57.40  ? 684 GLU A CG  1 
ATOM   3652  C CD  . GLU A 1 482 ? -31.022 -22.929 75.695 1.00 64.11  ? 684 GLU A CD  1 
ATOM   3653  O OE1 . GLU A 1 482 ? -29.777 -22.858 75.667 1.00 67.16  ? 684 GLU A OE1 1 
ATOM   3654  O OE2 . GLU A 1 482 ? -31.695 -22.627 76.701 1.00 67.99  ? 684 GLU A OE2 1 
ATOM   3655  N N   . TRP A 1 483 ? -33.725 -23.714 71.453 1.00 50.21  ? 685 TRP A N   1 
ATOM   3656  C CA  . TRP A 1 483 ? -34.775 -22.915 70.840 1.00 49.86  ? 685 TRP A CA  1 
ATOM   3657  C C   . TRP A 1 483 ? -35.619 -22.251 71.919 1.00 50.80  ? 685 TRP A C   1 
ATOM   3658  O O   . TRP A 1 483 ? -36.029 -22.901 72.884 1.00 50.71  ? 685 TRP A O   1 
ATOM   3659  C CB  . TRP A 1 483 ? -35.664 -23.787 69.952 1.00 45.73  ? 685 TRP A CB  1 
ATOM   3660  C CG  . TRP A 1 483 ? -34.961 -24.361 68.766 1.00 44.73  ? 685 TRP A CG  1 
ATOM   3661  C CD1 . TRP A 1 483 ? -34.316 -25.557 68.701 1.00 44.66  ? 685 TRP A CD1 1 
ATOM   3662  C CD2 . TRP A 1 483 ? -34.855 -23.777 67.464 1.00 44.04  ? 685 TRP A CD2 1 
ATOM   3663  N NE1 . TRP A 1 483 ? -33.800 -25.750 67.445 1.00 43.73  ? 685 TRP A NE1 1 
ATOM   3664  C CE2 . TRP A 1 483 ? -34.119 -24.671 66.666 1.00 44.33  ? 685 TRP A CE2 1 
ATOM   3665  C CE3 . TRP A 1 483 ? -35.304 -22.582 66.899 1.00 44.23  ? 685 TRP A CE3 1 
ATOM   3666  C CZ2 . TRP A 1 483 ? -33.822 -24.409 65.333 1.00 44.56  ? 685 TRP A CZ2 1 
ATOM   3667  C CZ3 . TRP A 1 483 ? -35.011 -22.325 65.576 1.00 44.52  ? 685 TRP A CZ3 1 
ATOM   3668  C CH2 . TRP A 1 483 ? -34.276 -23.233 64.808 1.00 45.16  ? 685 TRP A CH2 1 
ATOM   3669  N N   . GLU A 1 484 ? -35.880 -20.959 71.750 1.00 49.68  ? 686 GLU A N   1 
ATOM   3670  C CA  . GLU A 1 484 ? -36.725 -20.208 72.666 1.00 51.37  ? 686 GLU A CA  1 
ATOM   3671  C C   . GLU A 1 484 ? -38.131 -20.099 72.092 1.00 50.03  ? 686 GLU A C   1 
ATOM   3672  O O   . GLU A 1 484 ? -38.304 -19.824 70.903 1.00 48.97  ? 686 GLU A O   1 
ATOM   3673  C CB  . GLU A 1 484 ? -36.155 -18.812 72.925 1.00 47.62  ? 686 GLU A CB  1 
ATOM   3674  C CG  . GLU A 1 484 ? -36.940 -17.999 73.943 1.00 56.35  ? 686 GLU A CG  1 
ATOM   3675  C CD  . GLU A 1 484 ? -36.322 -16.640 74.209 1.00 62.19  ? 686 GLU A CD  1 
ATOM   3676  O OE1 . GLU A 1 484 ? -35.311 -16.305 73.563 1.00 63.99  ? 686 GLU A OE1 1 
ATOM   3677  O OE2 . GLU A 1 484 ? -36.844 -15.904 75.070 1.00 63.96  ? 686 GLU A OE2 1 
ATOM   3678  N N   . LEU A 1 485 ? -39.130 -20.314 72.942 1.00 49.03  ? 687 LEU A N   1 
ATOM   3679  C CA  . LEU A 1 485 ? -40.525 -20.325 72.533 1.00 49.70  ? 687 LEU A CA  1 
ATOM   3680  C C   . LEU A 1 485 ? -41.226 -19.056 72.994 1.00 52.58  ? 687 LEU A C   1 
ATOM   3681  O O   . LEU A 1 485 ? -40.901 -18.494 74.043 1.00 53.28  ? 687 LEU A O   1 
ATOM   3682  C CB  . LEU A 1 485 ? -41.262 -21.530 73.114 1.00 53.68  ? 687 LEU A CB  1 
ATOM   3683  C CG  . LEU A 1 485 ? -40.729 -22.909 72.756 1.00 51.59  ? 687 LEU A CG  1 
ATOM   3684  C CD1 . LEU A 1 485 ? -41.586 -23.968 73.426 1.00 50.52  ? 687 LEU A CD1 1 
ATOM   3685  C CD2 . LEU A 1 485 ? -40.684 -23.085 71.259 1.00 50.93  ? 687 LEU A CD2 1 
ATOM   3686  N N   . GLN A 1 486 ? -42.198 -18.613 72.207 1.00 44.91  ? 688 GLN A N   1 
ATOM   3687  C CA  . GLN A 1 486 ? -43.024 -17.485 72.613 1.00 48.22  ? 688 GLN A CA  1 
ATOM   3688  C C   . GLN A 1 486 ? -44.416 -17.955 73.023 1.00 50.28  ? 688 GLN A C   1 
ATOM   3689  O O   . GLN A 1 486 ? -45.146 -18.540 72.224 1.00 51.07  ? 688 GLN A O   1 
ATOM   3690  C CB  . GLN A 1 486 ? -43.128 -16.452 71.494 1.00 45.07  ? 688 GLN A CB  1 
ATOM   3691  C CG  . GLN A 1 486 ? -43.869 -15.198 71.910 1.00 50.67  ? 688 GLN A CG  1 
ATOM   3692  C CD  . GLN A 1 486 ? -43.843 -14.124 70.848 1.00 55.76  ? 688 GLN A CD  1 
ATOM   3693  O OE1 . GLN A 1 486 ? -43.201 -14.276 69.811 1.00 58.36  ? 688 GLN A OE1 1 
ATOM   3694  N NE2 . GLN A 1 486 ? -44.542 -13.026 71.102 1.00 56.95  ? 688 GLN A NE2 1 
ATOM   3695  N N   . PHE B 1 215 ? -48.249 5.671   78.058 1.00 55.98  ? 417 PHE B N   1 
ATOM   3696  C CA  . PHE B 1 215 ? -47.858 5.676   76.654 1.00 55.91  ? 417 PHE B CA  1 
ATOM   3697  C C   . PHE B 1 215 ? -46.395 5.298   76.486 1.00 58.67  ? 417 PHE B C   1 
ATOM   3698  O O   . PHE B 1 215 ? -45.535 5.786   77.214 1.00 58.24  ? 417 PHE B O   1 
ATOM   3699  C CB  . PHE B 1 215 ? -48.098 7.048   76.025 1.00 58.29  ? 417 PHE B CB  1 
ATOM   3700  C CG  . PHE B 1 215 ? -49.539 7.456   75.975 1.00 55.29  ? 417 PHE B CG  1 
ATOM   3701  C CD1 . PHE B 1 215 ? -50.354 7.044   74.937 1.00 53.73  ? 417 PHE B CD1 1 
ATOM   3702  C CD2 . PHE B 1 215 ? -50.074 8.268   76.957 1.00 54.49  ? 417 PHE B CD2 1 
ATOM   3703  C CE1 . PHE B 1 215 ? -51.676 7.425   74.886 1.00 52.65  ? 417 PHE B CE1 1 
ATOM   3704  C CE2 . PHE B 1 215 ? -51.395 8.651   76.910 1.00 52.95  ? 417 PHE B CE2 1 
ATOM   3705  C CZ  . PHE B 1 215 ? -52.197 8.229   75.873 1.00 52.76  ? 417 PHE B CZ  1 
ATOM   3706  N N   . GLU B 1 216 ? -46.117 4.428   75.522 1.00 55.15  ? 418 GLU B N   1 
ATOM   3707  C CA  . GLU B 1 216 ? -44.739 4.135   75.168 1.00 59.23  ? 418 GLU B CA  1 
ATOM   3708  C C   . GLU B 1 216 ? -44.137 5.305   74.398 1.00 59.28  ? 418 GLU B C   1 
ATOM   3709  O O   . GLU B 1 216 ? -44.845 6.155   73.853 1.00 58.87  ? 418 GLU B O   1 
ATOM   3710  C CB  . GLU B 1 216 ? -44.647 2.849   74.348 1.00 51.12  ? 418 GLU B CB  1 
ATOM   3711  C CG  . GLU B 1 216 ? -45.382 2.890   73.024 1.00 58.37  ? 418 GLU B CG  1 
ATOM   3712  C CD  . GLU B 1 216 ? -45.332 1.562   72.299 1.00 63.42  ? 418 GLU B CD  1 
ATOM   3713  O OE1 . GLU B 1 216 ? -44.455 0.738   72.629 1.00 66.79  ? 418 GLU B OE1 1 
ATOM   3714  O OE2 . GLU B 1 216 ? -46.174 1.335   71.406 1.00 65.18  ? 418 GLU B OE2 1 
ATOM   3715  N N   . ASN B 1 217 ? -42.808 5.344   74.372 1.00 60.20  ? 419 ASN B N   1 
ATOM   3716  C CA  . ASN B 1 217 ? -42.095 6.468   73.779 1.00 61.37  ? 419 ASN B CA  1 
ATOM   3717  C C   . ASN B 1 217 ? -42.433 6.605   72.300 1.00 60.14  ? 419 ASN B C   1 
ATOM   3718  O O   . ASN B 1 217 ? -42.289 5.653   71.527 1.00 60.69  ? 419 ASN B O   1 
ATOM   3719  C CB  . ASN B 1 217 ? -40.590 6.281   73.968 1.00 60.34  ? 419 ASN B CB  1 
ATOM   3720  C CG  . ASN B 1 217 ? -39.804 7.534   73.652 1.00 65.74  ? 419 ASN B CG  1 
ATOM   3721  O OD1 . ASN B 1 217 ? -40.284 8.649   73.848 1.00 68.72  ? 419 ASN B OD1 1 
ATOM   3722  N ND2 . ASN B 1 217 ? -38.588 7.358   73.153 1.00 68.08  ? 419 ASN B ND2 1 
ATOM   3723  N N   . VAL B 1 218 ? -42.881 7.794   71.913 1.00 59.78  ? 420 VAL B N   1 
ATOM   3724  C CA  . VAL B 1 218 ? -43.194 8.102   70.520 1.00 58.25  ? 420 VAL B CA  1 
ATOM   3725  C C   . VAL B 1 218 ? -42.450 9.374   70.139 1.00 56.89  ? 420 VAL B C   1 
ATOM   3726  O O   . VAL B 1 218 ? -42.189 10.239  70.991 1.00 56.89  ? 420 VAL B O   1 
ATOM   3727  C CB  . VAL B 1 218 ? -44.716 8.260   70.294 1.00 54.55  ? 420 VAL B CB  1 
ATOM   3728  C CG1 . VAL B 1 218 ? -45.426 6.944   70.530 1.00 57.52  ? 420 VAL B CG1 1 
ATOM   3729  C CG2 . VAL B 1 218 ? -45.281 9.337   71.201 1.00 55.69  ? 420 VAL B CG2 1 
ATOM   3730  N N   . PRO B 1 219 ? -42.079 9.514   68.868 1.00 56.53  ? 421 PRO B N   1 
ATOM   3731  C CA  . PRO B 1 219 ? -41.388 10.732  68.442 1.00 55.25  ? 421 PRO B CA  1 
ATOM   3732  C C   . PRO B 1 219 ? -42.311 11.935  68.511 1.00 54.51  ? 421 PRO B C   1 
ATOM   3733  O O   . PRO B 1 219 ? -43.513 11.842  68.254 1.00 55.12  ? 421 PRO B O   1 
ATOM   3734  C CB  . PRO B 1 219 ? -40.982 10.421  66.999 1.00 53.34  ? 421 PRO B CB  1 
ATOM   3735  C CG  . PRO B 1 219 ? -41.990 9.431   66.543 1.00 53.91  ? 421 PRO B CG  1 
ATOM   3736  C CD  . PRO B 1 219 ? -42.300 8.588   67.744 1.00 53.62  ? 421 PRO B CD  1 
ATOM   3737  N N   . PHE B 1 220 ? -41.734 13.074  68.884 1.00 52.91  ? 422 PHE B N   1 
ATOM   3738  C CA  . PHE B 1 220 ? -42.507 14.304  68.964 1.00 50.93  ? 422 PHE B CA  1 
ATOM   3739  C C   . PHE B 1 220 ? -43.160 14.609  67.626 1.00 50.60  ? 422 PHE B C   1 
ATOM   3740  O O   . PHE B 1 220 ? -42.498 14.637  66.586 1.00 50.54  ? 422 PHE B O   1 
ATOM   3741  C CB  . PHE B 1 220 ? -41.613 15.470  69.382 1.00 53.09  ? 422 PHE B CB  1 
ATOM   3742  C CG  . PHE B 1 220 ? -41.093 15.363  70.781 1.00 54.74  ? 422 PHE B CG  1 
ATOM   3743  C CD1 . PHE B 1 220 ? -41.835 15.840  71.846 1.00 54.70  ? 422 PHE B CD1 1 
ATOM   3744  C CD2 . PHE B 1 220 ? -39.869 14.772  71.034 1.00 54.77  ? 422 PHE B CD2 1 
ATOM   3745  C CE1 . PHE B 1 220 ? -41.361 15.743  73.136 1.00 54.54  ? 422 PHE B CE1 1 
ATOM   3746  C CE2 . PHE B 1 220 ? -39.391 14.668  72.324 1.00 53.93  ? 422 PHE B CE2 1 
ATOM   3747  C CZ  . PHE B 1 220 ? -40.138 15.155  73.376 1.00 54.19  ? 422 PHE B CZ  1 
ATOM   3748  N N   . HIS B 1 221 ? -44.461 14.862  67.647 1.00 46.97  ? 423 HIS B N   1 
ATOM   3749  C CA  . HIS B 1 221 ? -45.140 15.206  66.416 1.00 47.11  ? 423 HIS B CA  1 
ATOM   3750  C C   . HIS B 1 221 ? -44.649 16.574  65.975 1.00 47.80  ? 423 HIS B C   1 
ATOM   3751  O O   . HIS B 1 221 ? -44.569 17.499  66.774 1.00 47.98  ? 423 HIS B O   1 
ATOM   3752  C CB  . HIS B 1 221 ? -46.653 15.243  66.587 1.00 40.91  ? 423 HIS B CB  1 
ATOM   3753  C CG  . HIS B 1 221 ? -47.363 15.809  65.400 1.00 42.57  ? 423 HIS B CG  1 
ATOM   3754  N ND1 . HIS B 1 221 ? -47.465 15.132  64.206 1.00 43.67  ? 423 HIS B ND1 1 
ATOM   3755  C CD2 . HIS B 1 221 ? -47.973 17.001  65.209 1.00 42.90  ? 423 HIS B CD2 1 
ATOM   3756  C CE1 . HIS B 1 221 ? -48.124 15.874  63.336 1.00 44.29  ? 423 HIS B CE1 1 
ATOM   3757  N NE2 . HIS B 1 221 ? -48.441 17.015  63.919 1.00 44.14  ? 423 HIS B NE2 1 
ATOM   3758  N N   . SER B 1 222 ? -44.319 16.703  64.701 1.00 45.21  ? 424 SER B N   1 
ATOM   3759  C CA  . SER B 1 222 ? -43.838 17.965  64.189 1.00 45.53  ? 424 SER B CA  1 
ATOM   3760  C C   . SER B 1 222 ? -45.002 18.880  63.902 1.00 44.96  ? 424 SER B C   1 
ATOM   3761  O O   . SER B 1 222 ? -45.917 18.513  63.174 1.00 45.63  ? 424 SER B O   1 
ATOM   3762  C CB  . SER B 1 222 ? -43.097 17.726  62.885 1.00 42.65  ? 424 SER B CB  1 
ATOM   3763  O OG  . SER B 1 222 ? -44.014 17.411  61.860 1.00 46.24  ? 424 SER B OG  1 
ATOM   3764  N N   . SER B 1 223 ? -44.961 20.086  64.451 1.00 45.16  ? 425 SER B N   1 
ATOM   3765  C CA  . SER B 1 223 ? -46.020 21.048  64.198 1.00 44.81  ? 425 SER B CA  1 
ATOM   3766  C C   . SER B 1 223 ? -45.353 22.341  63.794 1.00 43.98  ? 425 SER B C   1 
ATOM   3767  O O   . SER B 1 223 ? -45.394 23.339  64.504 1.00 44.69  ? 425 SER B O   1 
ATOM   3768  C CB  . SER B 1 223 ? -46.907 21.242  65.427 1.00 45.61  ? 425 SER B CB  1 
ATOM   3769  O OG  . SER B 1 223 ? -46.136 21.431  66.596 1.00 47.76  ? 425 SER B OG  1 
ATOM   3770  N N   . TYR B 1 224 ? -44.735 22.296  62.623 1.00 44.09  ? 426 TYR B N   1 
ATOM   3771  C CA  . TYR B 1 224 ? -44.031 23.426  62.060 1.00 44.53  ? 426 TYR B CA  1 
ATOM   3772  C C   . TYR B 1 224 ? -44.004 23.257  60.552 1.00 44.46  ? 426 TYR B C   1 
ATOM   3773  O O   . TYR B 1 224 ? -44.188 22.156  60.045 1.00 44.83  ? 426 TYR B O   1 
ATOM   3774  C CB  . TYR B 1 224 ? -42.609 23.483  62.609 1.00 36.83  ? 426 TYR B CB  1 
ATOM   3775  C CG  . TYR B 1 224 ? -41.823 22.211  62.399 1.00 38.21  ? 426 TYR B CG  1 
ATOM   3776  C CD1 . TYR B 1 224 ? -41.373 21.852  61.139 1.00 38.67  ? 426 TYR B CD1 1 
ATOM   3777  C CD2 . TYR B 1 224 ? -41.530 21.372  63.458 1.00 39.01  ? 426 TYR B CD2 1 
ATOM   3778  C CE1 . TYR B 1 224 ? -40.654 20.692  60.940 1.00 40.99  ? 426 TYR B CE1 1 
ATOM   3779  C CE2 . TYR B 1 224 ? -40.811 20.211  63.269 1.00 41.01  ? 426 TYR B CE2 1 
ATOM   3780  C CZ  . TYR B 1 224 ? -40.377 19.875  62.007 1.00 41.88  ? 426 TYR B CZ  1 
ATOM   3781  O OH  . TYR B 1 224 ? -39.660 18.721  61.813 1.00 43.19  ? 426 TYR B OH  1 
ATOM   3782  N N   . ALA B 1 225 ? -43.784 24.348  59.834 1.00 43.22  ? 427 ALA B N   1 
ATOM   3783  C CA  . ALA B 1 225 ? -43.715 24.302  58.385 1.00 43.19  ? 427 ALA B CA  1 
ATOM   3784  C C   . ALA B 1 225 ? -42.332 24.763  57.969 1.00 43.88  ? 427 ALA B C   1 
ATOM   3785  O O   . ALA B 1 225 ? -41.822 25.747  58.490 1.00 44.54  ? 427 ALA B O   1 
ATOM   3786  C CB  . ALA B 1 225 ? -44.783 25.181  57.770 1.00 46.86  ? 427 ALA B CB  1 
ATOM   3787  N N   . HIS B 1 226 ? -41.712 24.047  57.041 1.00 42.09  ? 428 HIS B N   1 
ATOM   3788  C CA  . HIS B 1 226 ? -40.373 24.415  56.608 1.00 42.13  ? 428 HIS B CA  1 
ATOM   3789  C C   . HIS B 1 226 ? -40.330 25.783  55.941 1.00 42.59  ? 428 HIS B C   1 
ATOM   3790  O O   . HIS B 1 226 ? -41.218 26.141  55.177 1.00 41.30  ? 428 HIS B O   1 
ATOM   3791  C CB  . HIS B 1 226 ? -39.777 23.338  55.700 1.00 36.29  ? 428 HIS B CB  1 
ATOM   3792  C CG  . HIS B 1 226 ? -39.489 22.054  56.408 1.00 37.43  ? 428 HIS B CG  1 
ATOM   3793  N ND1 . HIS B 1 226 ? -38.614 21.972  57.466 1.00 37.01  ? 428 HIS B ND1 1 
ATOM   3794  C CD2 . HIS B 1 226 ? -39.962 20.802  56.215 1.00 38.05  ? 428 HIS B CD2 1 
ATOM   3795  C CE1 . HIS B 1 226 ? -38.560 20.726  57.897 1.00 37.43  ? 428 HIS B CE1 1 
ATOM   3796  N NE2 . HIS B 1 226 ? -39.369 19.995  57.154 1.00 39.06  ? 428 HIS B NE2 1 
ATOM   3797  N N   . SER B 1 227 ? -39.285 26.544  56.250 1.00 40.77  ? 429 SER B N   1 
ATOM   3798  C CA  . SER B 1 227 ? -39.111 27.870  55.688 1.00 41.83  ? 429 SER B CA  1 
ATOM   3799  C C   . SER B 1 227 ? -38.209 27.783  54.478 1.00 42.01  ? 429 SER B C   1 
ATOM   3800  O O   . SER B 1 227 ? -37.784 28.796  53.937 1.00 42.55  ? 429 SER B O   1 
ATOM   3801  C CB  . SER B 1 227 ? -38.532 28.829  56.717 1.00 43.34  ? 429 SER B CB  1 
ATOM   3802  O OG  . SER B 1 227 ? -37.231 28.437  57.103 1.00 47.46  ? 429 SER B OG  1 
ATOM   3803  N N   . GLN B 1 228 ? -37.906 26.551  54.085 1.00 37.60  ? 430 GLN B N   1 
ATOM   3804  C CA  . GLN B 1 228 ? -37.109 26.252  52.908 1.00 38.90  ? 430 GLN B CA  1 
ATOM   3805  C C   . GLN B 1 228 ? -37.733 25.086  52.161 1.00 38.50  ? 430 GLN B C   1 
ATOM   3806  O O   . GLN B 1 228 ? -38.632 24.409  52.661 1.00 38.36  ? 430 GLN B O   1 
ATOM   3807  C CB  . GLN B 1 228 ? -35.658 25.920  53.263 1.00 34.65  ? 430 GLN B CB  1 
ATOM   3808  C CG  . GLN B 1 228 ? -34.852 27.105  53.712 1.00 35.40  ? 430 GLN B CG  1 
ATOM   3809  C CD  . GLN B 1 228 ? -33.440 26.729  54.091 1.00 35.94  ? 430 GLN B CD  1 
ATOM   3810  O OE1 . GLN B 1 228 ? -33.178 25.611  54.532 1.00 36.71  ? 430 GLN B OE1 1 
ATOM   3811  N NE2 . GLN B 1 228 ? -32.514 27.653  53.888 1.00 33.96  ? 430 GLN B NE2 1 
ATOM   3812  N N   . SER B 1 229 ? -37.246 24.870  50.946 1.00 34.55  ? 431 SER B N   1 
ATOM   3813  C CA  . SER B 1 229 ? -37.623 23.725  50.138 1.00 34.37  ? 431 SER B CA  1 
ATOM   3814  C C   . SER B 1 229 ? -36.406 22.838  49.923 1.00 34.11  ? 431 SER B C   1 
ATOM   3815  O O   . SER B 1 229 ? -35.264 23.293  50.015 1.00 33.40  ? 431 SER B O   1 
ATOM   3816  C CB  . SER B 1 229 ? -38.205 24.161  48.794 1.00 34.49  ? 431 SER B CB  1 
ATOM   3817  O OG  . SER B 1 229 ? -37.244 24.854  48.024 1.00 38.97  ? 431 SER B OG  1 
ATOM   3818  N N   . LEU B 1 230 ? -36.664 21.558  49.650 1.00 33.62  ? 432 LEU B N   1 
ATOM   3819  C CA  . LEU B 1 230 ? -35.583 20.583  49.566 1.00 33.01  ? 432 LEU B CA  1 
ATOM   3820  C C   . LEU B 1 230 ? -34.600 20.919  48.456 1.00 33.94  ? 432 LEU B C   1 
ATOM   3821  O O   . LEU B 1 230 ? -33.405 20.628  48.577 1.00 34.24  ? 432 LEU B O   1 
ATOM   3822  C CB  . LEU B 1 230 ? -36.158 19.188  49.339 1.00 30.26  ? 432 LEU B CB  1 
ATOM   3823  C CG  . LEU B 1 230 ? -35.210 18.005  49.501 1.00 31.00  ? 432 LEU B CG  1 
ATOM   3824  C CD1 . LEU B 1 230 ? -34.237 18.265  50.633 1.00 30.68  ? 432 LEU B CD1 1 
ATOM   3825  C CD2 . LEU B 1 230 ? -36.015 16.772  49.792 1.00 31.38  ? 432 LEU B CD2 1 
ATOM   3826  N N   . ASP B 1 231 ? -35.076 21.512  47.369 1.00 34.45  ? 433 ASP B N   1 
ATOM   3827  C CA  . ASP B 1 231 ? -34.244 21.782  46.207 1.00 36.52  ? 433 ASP B CA  1 
ATOM   3828  C C   . ASP B 1 231 ? -33.595 23.162  46.223 1.00 35.84  ? 433 ASP B C   1 
ATOM   3829  O O   . ASP B 1 231 ? -32.750 23.440  45.369 1.00 36.91  ? 433 ASP B O   1 
ATOM   3830  C CB  . ASP B 1 231 ? -35.075 21.596  44.934 1.00 33.14  ? 433 ASP B CB  1 
ATOM   3831  C CG  . ASP B 1 231 ? -36.351 22.408  44.948 1.00 37.37  ? 433 ASP B CG  1 
ATOM   3832  O OD1 . ASP B 1 231 ? -36.652 23.032  45.985 1.00 39.42  ? 433 ASP B OD1 1 
ATOM   3833  O OD2 . ASP B 1 231 ? -37.065 22.410  43.924 1.00 40.81  ? 433 ASP B OD2 1 
ATOM   3834  N N   . ARG B 1 232 ? -33.982 24.038  47.147 1.00 36.19  ? 434 ARG B N   1 
ATOM   3835  C CA  . ARG B 1 232 ? -33.382 25.360  47.278 1.00 34.53  ? 434 ARG B CA  1 
ATOM   3836  C C   . ARG B 1 232 ? -32.340 25.468  48.389 1.00 34.25  ? 434 ARG B C   1 
ATOM   3837  O O   . ARG B 1 232 ? -31.894 26.578  48.689 1.00 34.09  ? 434 ARG B O   1 
ATOM   3838  C CB  . ARG B 1 232 ? -34.470 26.418  47.442 1.00 37.21  ? 434 ARG B CB  1 
ATOM   3839  C CG  . ARG B 1 232 ? -35.278 26.556  46.168 1.00 39.25  ? 434 ARG B CG  1 
ATOM   3840  C CD  . ARG B 1 232 ? -34.392 27.146  45.084 1.00 37.86  ? 434 ARG B CD  1 
ATOM   3841  N NE  . ARG B 1 232 ? -35.031 27.181  43.774 1.00 37.78  ? 434 ARG B NE  1 
ATOM   3842  C CZ  . ARG B 1 232 ? -34.894 26.225  42.862 1.00 37.74  ? 434 ARG B CZ  1 
ATOM   3843  N NH1 . ARG B 1 232 ? -34.141 25.168  43.123 1.00 36.62  ? 434 ARG B NH1 1 
ATOM   3844  N NH2 . ARG B 1 232 ? -35.500 26.326  41.690 1.00 39.79  ? 434 ARG B NH2 1 
ATOM   3845  N N   . LEU B 1 233 ? -31.950 24.356  49.016 1.00 31.71  ? 435 LEU B N   1 
ATOM   3846  C CA  . LEU B 1 233 ? -31.040 24.398  50.160 1.00 31.57  ? 435 LEU B CA  1 
ATOM   3847  C C   . LEU B 1 233 ? -29.698 25.059  49.857 1.00 32.37  ? 435 LEU B C   1 
ATOM   3848  O O   . LEU B 1 233 ? -28.942 25.332  50.795 1.00 33.24  ? 435 LEU B O   1 
ATOM   3849  C CB  . LEU B 1 233 ? -30.786 22.985  50.680 1.00 32.37  ? 435 LEU B CB  1 
ATOM   3850  C CG  . LEU B 1 233 ? -31.986 22.223  51.237 1.00 32.90  ? 435 LEU B CG  1 
ATOM   3851  C CD1 . LEU B 1 233 ? -31.575 20.819  51.624 1.00 30.74  ? 435 LEU B CD1 1 
ATOM   3852  C CD2 . LEU B 1 233 ? -32.591 22.953  52.421 1.00 32.37  ? 435 LEU B CD2 1 
ATOM   3853  N N   . MET B 1 234 ? -29.386 25.317  48.592 1.00 31.71  ? 436 MET B N   1 
ATOM   3854  C CA  . MET B 1 234 ? -28.081 25.797  48.166 1.00 32.77  ? 436 MET B CA  1 
ATOM   3855  C C   . MET B 1 234 ? -27.809 27.225  48.631 1.00 32.87  ? 436 MET B C   1 
ATOM   3856  O O   . MET B 1 234 ? -28.710 27.972  49.017 1.00 32.84  ? 436 MET B O   1 
ATOM   3857  C CB  . MET B 1 234 ? -27.973 25.750  46.649 1.00 31.76  ? 436 MET B CB  1 
ATOM   3858  C CG  . MET B 1 234 ? -28.894 26.737  45.982 1.00 33.81  ? 436 MET B CG  1 
ATOM   3859  S SD  . MET B 1 234 ? -29.027 26.473  44.217 1.00 38.44  ? 436 MET B SD  1 
ATOM   3860  C CE  . MET B 1 234 ? -30.262 25.182  44.190 1.00 37.82  ? 436 MET B CE  1 
ATOM   3861  N N   . ASN B 1 235 ? -26.529 27.581  48.602 1.00 30.86  ? 437 ASN B N   1 
ATOM   3862  C CA  . ASN B 1 235 ? -26.092 28.969  48.701 1.00 29.55  ? 437 ASN B CA  1 
ATOM   3863  C C   . ASN B 1 235 ? -26.286 29.647  47.350 1.00 28.87  ? 437 ASN B C   1 
ATOM   3864  O O   . ASN B 1 235 ? -25.681 29.219  46.362 1.00 29.22  ? 437 ASN B O   1 
ATOM   3865  C CB  . ASN B 1 235 ? -24.625 29.026  49.119 1.00 30.13  ? 437 ASN B CB  1 
ATOM   3866  C CG  . ASN B 1 235 ? -24.135 30.439  49.404 1.00 30.66  ? 437 ASN B CG  1 
ATOM   3867  O OD1 . ASN B 1 235 ? -24.716 31.422  48.958 1.00 30.96  ? 437 ASN B OD1 1 
ATOM   3868  N ND2 . ASN B 1 235 ? -23.048 30.538  50.153 1.00 30.36  ? 437 ASN B ND2 1 
ATOM   3869  N N   . PRO B 1 236 ? -27.113 30.690  47.258 1.00 30.76  ? 438 PRO B N   1 
ATOM   3870  C CA  . PRO B 1 236 ? -27.381 31.316  45.954 1.00 30.09  ? 438 PRO B CA  1 
ATOM   3871  C C   . PRO B 1 236 ? -26.211 32.090  45.375 1.00 30.26  ? 438 PRO B C   1 
ATOM   3872  O O   . PRO B 1 236 ? -26.256 32.436  44.191 1.00 30.87  ? 438 PRO B O   1 
ATOM   3873  C CB  . PRO B 1 236 ? -28.554 32.252  46.255 1.00 30.89  ? 438 PRO B CB  1 
ATOM   3874  C CG  . PRO B 1 236 ? -28.387 32.583  47.695 1.00 31.40  ? 438 PRO B CG  1 
ATOM   3875  C CD  . PRO B 1 236 ? -27.854 31.345  48.347 1.00 31.49  ? 438 PRO B CD  1 
ATOM   3876  N N   . LEU B 1 237 ? -25.195 32.414  46.166 1.00 31.77  ? 439 LEU B N   1 
ATOM   3877  C CA  . LEU B 1 237 ? -24.148 33.314  45.706 1.00 31.09  ? 439 LEU B CA  1 
ATOM   3878  C C   . LEU B 1 237 ? -22.939 32.599  45.115 1.00 32.52  ? 439 LEU B C   1 
ATOM   3879  O O   . LEU B 1 237 ? -22.080 33.254  44.516 1.00 32.94  ? 439 LEU B O   1 
ATOM   3880  C CB  . LEU B 1 237 ? -23.697 34.202  46.867 1.00 33.12  ? 439 LEU B CB  1 
ATOM   3881  C CG  . LEU B 1 237 ? -24.796 35.087  47.458 1.00 32.40  ? 439 LEU B CG  1 
ATOM   3882  C CD1 . LEU B 1 237 ? -24.295 35.827  48.683 1.00 30.33  ? 439 LEU B CD1 1 
ATOM   3883  C CD2 . LEU B 1 237 ? -25.324 36.057  46.419 1.00 29.96  ? 439 LEU B CD2 1 
ATOM   3884  N N   . ILE B 1 238 ? -22.854 31.276  45.245 1.00 30.52  ? 440 ILE B N   1 
ATOM   3885  C CA  . ILE B 1 238 ? -21.624 30.533  44.991 1.00 31.57  ? 440 ILE B CA  1 
ATOM   3886  C C   . ILE B 1 238 ? -21.886 29.433  43.970 1.00 33.43  ? 440 ILE B C   1 
ATOM   3887  O O   . ILE B 1 238 ? -22.977 28.855  43.928 1.00 34.74  ? 440 ILE B O   1 
ATOM   3888  C CB  . ILE B 1 238 ? -21.065 29.950  46.304 1.00 31.46  ? 440 ILE B CB  1 
ATOM   3889  C CG1 . ILE B 1 238 ? -20.848 31.066  47.328 1.00 29.40  ? 440 ILE B CG1 1 
ATOM   3890  C CG2 . ILE B 1 238 ? -19.764 29.210  46.069 1.00 31.12  ? 440 ILE B CG2 1 
ATOM   3891  C CD1 . ILE B 1 238 ? -19.897 32.143  46.868 1.00 26.89  ? 440 ILE B CD1 1 
ATOM   3892  N N   . ASP B 1 239 ? -20.880 29.154  43.141 1.00 30.19  ? 441 ASP B N   1 
ATOM   3893  C CA  . ASP B 1 239 ? -20.936 28.038  42.207 1.00 31.30  ? 441 ASP B CA  1 
ATOM   3894  C C   . ASP B 1 239 ? -20.653 26.719  42.915 1.00 29.92  ? 441 ASP B C   1 
ATOM   3895  O O   . ASP B 1 239 ? -19.972 26.671  43.941 1.00 30.89  ? 441 ASP B O   1 
ATOM   3896  C CB  . ASP B 1 239 ? -19.911 28.218  41.088 1.00 27.73  ? 441 ASP B CB  1 
ATOM   3897  C CG  . ASP B 1 239 ? -20.268 29.332  40.135 1.00 34.24  ? 441 ASP B CG  1 
ATOM   3898  O OD1 . ASP B 1 239 ? -21.440 29.751  40.118 1.00 40.86  ? 441 ASP B OD1 1 
ATOM   3899  O OD2 . ASP B 1 239 ? -19.369 29.791  39.401 1.00 35.79  ? 441 ASP B OD2 1 
ATOM   3900  N N   . GLN B 1 240 ? -21.197 25.640  42.362 1.00 28.75  ? 442 GLN B N   1 
ATOM   3901  C CA  . GLN B 1 240 ? -20.719 24.310  42.694 1.00 27.51  ? 442 GLN B CA  1 
ATOM   3902  C C   . GLN B 1 240 ? -19.433 24.009  41.930 1.00 27.39  ? 442 GLN B C   1 
ATOM   3903  O O   . GLN B 1 240 ? -19.135 24.620  40.902 1.00 27.36  ? 442 GLN B O   1 
ATOM   3904  C CB  . GLN B 1 240 ? -21.769 23.245  42.375 1.00 26.85  ? 442 GLN B CB  1 
ATOM   3905  C CG  . GLN B 1 240 ? -23.002 23.283  43.249 1.00 25.09  ? 442 GLN B CG  1 
ATOM   3906  C CD  . GLN B 1 240 ? -23.980 22.187  42.900 1.00 25.22  ? 442 GLN B CD  1 
ATOM   3907  O OE1 . GLN B 1 240 ? -23.973 21.666  41.787 1.00 24.13  ? 442 GLN B OE1 1 
ATOM   3908  N NE2 . GLN B 1 240 ? -24.828 21.826  43.853 1.00 25.34  ? 442 GLN B NE2 1 
ATOM   3909  N N   . TYR B 1 241 ? -18.661 23.060  42.452 1.00 19.95  ? 443 TYR B N   1 
ATOM   3910  C CA  . TYR B 1 241 ? -17.526 22.506  41.727 1.00 18.51  ? 443 TYR B CA  1 
ATOM   3911  C C   . TYR B 1 241 ? -17.915 21.315  40.872 1.00 18.14  ? 443 TYR B C   1 
ATOM   3912  O O   . TYR B 1 241 ? -17.039 20.640  40.326 1.00 19.42  ? 443 TYR B O   1 
ATOM   3913  C CB  . TYR B 1 241 ? -16.391 22.135  42.682 1.00 19.98  ? 443 TYR B CB  1 
ATOM   3914  C CG  . TYR B 1 241 ? -16.756 21.234  43.830 1.00 19.54  ? 443 TYR B CG  1 
ATOM   3915  C CD1 . TYR B 1 241 ? -16.732 19.857  43.701 1.00 19.14  ? 443 TYR B CD1 1 
ATOM   3916  C CD2 . TYR B 1 241 ? -17.084 21.768  45.064 1.00 20.41  ? 443 TYR B CD2 1 
ATOM   3917  C CE1 . TYR B 1 241 ? -17.058 19.039  44.765 1.00 19.30  ? 443 TYR B CE1 1 
ATOM   3918  C CE2 . TYR B 1 241 ? -17.408 20.963  46.127 1.00 20.47  ? 443 TYR B CE2 1 
ATOM   3919  C CZ  . TYR B 1 241 ? -17.393 19.603  45.975 1.00 20.09  ? 443 TYR B CZ  1 
ATOM   3920  O OH  . TYR B 1 241 ? -17.716 18.812  47.049 1.00 19.92  ? 443 TYR B OH  1 
ATOM   3921  N N   . LEU B 1 242 ? -19.203 21.029  40.769 1.00 18.65  ? 444 LEU B N   1 
ATOM   3922  C CA  . LEU B 1 242 ? -19.711 19.969  39.920 1.00 18.80  ? 444 LEU B CA  1 
ATOM   3923  C C   . LEU B 1 242 ? -20.143 20.532  38.573 1.00 19.41  ? 444 LEU B C   1 
ATOM   3924  O O   . LEU B 1 242 ? -20.658 21.646  38.480 1.00 19.70  ? 444 LEU B O   1 
ATOM   3925  C CB  . LEU B 1 242 ? -20.887 19.263  40.593 1.00 20.45  ? 444 LEU B CB  1 
ATOM   3926  C CG  . LEU B 1 242 ? -20.559 18.573  41.917 1.00 19.87  ? 444 LEU B CG  1 
ATOM   3927  C CD1 . LEU B 1 242 ? -21.824 18.051  42.552 1.00 19.14  ? 444 LEU B CD1 1 
ATOM   3928  C CD2 . LEU B 1 242 ? -19.549 17.454  41.724 1.00 19.08  ? 444 LEU B CD2 1 
ATOM   3929  N N   . TYR B 1 243 ? -19.927 19.741  37.531 1.00 16.51  ? 445 TYR B N   1 
ATOM   3930  C CA  . TYR B 1 243 ? -20.313 20.071  36.171 1.00 16.53  ? 445 TYR B CA  1 
ATOM   3931  C C   . TYR B 1 243 ? -21.428 19.134  35.737 1.00 16.56  ? 445 TYR B C   1 
ATOM   3932  O O   . TYR B 1 243 ? -21.588 18.040  36.281 1.00 16.52  ? 445 TYR B O   1 
ATOM   3933  C CB  . TYR B 1 243 ? -19.128 19.941  35.200 1.00 14.08  ? 445 TYR B CB  1 
ATOM   3934  C CG  . TYR B 1 243 ? -18.097 21.044  35.245 1.00 16.27  ? 445 TYR B CG  1 
ATOM   3935  C CD1 . TYR B 1 243 ? -18.063 22.024  34.268 1.00 17.46  ? 445 TYR B CD1 1 
ATOM   3936  C CD2 . TYR B 1 243 ? -17.183 21.128  36.278 1.00 16.55  ? 445 TYR B CD2 1 
ATOM   3937  C CE1 . TYR B 1 243 ? -17.126 23.028  34.294 1.00 18.22  ? 445 TYR B CE1 1 
ATOM   3938  C CE2 . TYR B 1 243 ? -16.259 22.144  36.327 1.00 17.26  ? 445 TYR B CE2 1 
ATOM   3939  C CZ  . TYR B 1 243 ? -16.228 23.086  35.329 1.00 17.96  ? 445 TYR B CZ  1 
ATOM   3940  O OH  . TYR B 1 243 ? -15.298 24.096  35.374 1.00 19.10  ? 445 TYR B OH  1 
ATOM   3941  N N   . TYR B 1 244 ? -22.205 19.579  34.761 1.00 15.40  ? 446 TYR B N   1 
ATOM   3942  C CA  . TYR B 1 244 ? -23.281 18.801  34.176 1.00 15.75  ? 446 TYR B CA  1 
ATOM   3943  C C   . TYR B 1 244 ? -23.118 18.839  32.665 1.00 16.11  ? 446 TYR B C   1 
ATOM   3944  O O   . TYR B 1 244 ? -22.317 19.609  32.133 1.00 15.94  ? 446 TYR B O   1 
ATOM   3945  C CB  . TYR B 1 244 ? -24.653 19.352  34.583 1.00 15.79  ? 446 TYR B CB  1 
ATOM   3946  C CG  . TYR B 1 244 ? -24.947 20.717  34.013 1.00 16.17  ? 446 TYR B CG  1 
ATOM   3947  C CD1 . TYR B 1 244 ? -25.690 20.859  32.852 1.00 15.17  ? 446 TYR B CD1 1 
ATOM   3948  C CD2 . TYR B 1 244 ? -24.446 21.862  34.610 1.00 17.15  ? 446 TYR B CD2 1 
ATOM   3949  C CE1 . TYR B 1 244 ? -25.951 22.104  32.322 1.00 16.96  ? 446 TYR B CE1 1 
ATOM   3950  C CE2 . TYR B 1 244 ? -24.699 23.108  34.085 1.00 17.99  ? 446 TYR B CE2 1 
ATOM   3951  C CZ  . TYR B 1 244 ? -25.449 23.222  32.941 1.00 18.30  ? 446 TYR B CZ  1 
ATOM   3952  O OH  . TYR B 1 244 ? -25.702 24.463  32.414 1.00 18.90  ? 446 TYR B OH  1 
ATOM   3953  N N   . LEU B 1 245 ? -23.884 18.008  31.963 1.00 14.00  ? 447 LEU B N   1 
ATOM   3954  C CA  . LEU B 1 245 ? -23.783 17.980  30.508 1.00 15.67  ? 447 LEU B CA  1 
ATOM   3955  C C   . LEU B 1 245 ? -24.785 18.989  29.963 1.00 17.55  ? 447 LEU B C   1 
ATOM   3956  O O   . LEU B 1 245 ? -26.002 18.792  29.981 1.00 18.26  ? 447 LEU B O   1 
ATOM   3957  C CB  . LEU B 1 245 ? -24.039 16.576  29.980 1.00 14.84  ? 447 LEU B CB  1 
ATOM   3958  C CG  . LEU B 1 245 ? -24.089 16.404  28.464 1.00 15.14  ? 447 LEU B CG  1 
ATOM   3959  C CD1 . LEU B 1 245 ? -22.765 16.760  27.840 1.00 14.09  ? 447 LEU B CD1 1 
ATOM   3960  C CD2 . LEU B 1 245 ? -24.482 14.987  28.108 1.00 15.77  ? 447 LEU B CD2 1 
ATOM   3961  N N   . SER B 1 246 ? -24.245 20.106  29.471 1.00 16.88  ? 448 SER B N   1 
ATOM   3962  C CA  . SER B 1 246 ? -25.098 21.199  29.020 1.00 18.53  ? 448 SER B CA  1 
ATOM   3963  C C   . SER B 1 246 ? -25.552 21.005  27.581 1.00 20.16  ? 448 SER B C   1 
ATOM   3964  O O   . SER B 1 246 ? -26.714 21.264  27.248 1.00 21.45  ? 448 SER B O   1 
ATOM   3965  C CB  . SER B 1 246 ? -24.373 22.534  29.185 1.00 18.68  ? 448 SER B CB  1 
ATOM   3966  O OG  . SER B 1 246 ? -23.222 22.602  28.370 1.00 20.27  ? 448 SER B OG  1 
ATOM   3967  N N   . LYS B 1 247 ? -24.652 20.556  26.712 1.00 18.86  ? 449 LYS B N   1 
ATOM   3968  C CA  . LYS B 1 247 ? -24.852 20.639  25.273 1.00 20.49  ? 449 LYS B CA  1 
ATOM   3969  C C   . LYS B 1 247 ? -24.459 19.329  24.609 1.00 21.54  ? 449 LYS B C   1 
ATOM   3970  O O   . LYS B 1 247 ? -23.305 18.902  24.710 1.00 22.44  ? 449 LYS B O   1 
ATOM   3971  C CB  . LYS B 1 247 ? -24.034 21.797  24.700 1.00 17.39  ? 449 LYS B CB  1 
ATOM   3972  C CG  . LYS B 1 247 ? -24.226 22.023  23.229 1.00 19.76  ? 449 LYS B CG  1 
ATOM   3973  C CD  . LYS B 1 247 ? -23.295 23.096  22.705 1.00 22.56  ? 449 LYS B CD  1 
ATOM   3974  C CE  . LYS B 1 247 ? -23.679 24.460  23.233 1.00 25.34  ? 449 LYS B CE  1 
ATOM   3975  N NZ  . LYS B 1 247 ? -22.761 25.516  22.730 1.00 28.10  ? 449 LYS B NZ  1 
ATOM   3976  N N   . THR B 1 248 ? -25.425 18.678  23.951 1.00 24.28  ? 450 THR B N   1 
ATOM   3977  C CA  . THR B 1 248 ? -25.156 17.471  23.184 1.00 25.37  ? 450 THR B CA  1 
ATOM   3978  C C   . THR B 1 248 ? -25.028 17.678  21.680 1.00 26.62  ? 450 THR B C   1 
ATOM   3979  O O   . THR B 1 248 ? -24.711 16.713  20.976 1.00 26.60  ? 450 THR B O   1 
ATOM   3980  C CB  . THR B 1 248 ? -26.247 16.420  23.432 1.00 25.45  ? 450 THR B CB  1 
ATOM   3981  O OG1 . THR B 1 248 ? -27.521 16.958  23.068 1.00 26.11  ? 450 THR B OG1 1 
ATOM   3982  C CG2 . THR B 1 248 ? -26.272 16.009  24.890 1.00 24.63  ? 450 THR B CG2 1 
ATOM   3983  N N   . ILE B 1 249 ? -25.313 18.874  21.183 1.00 26.15  ? 451 ILE B N   1 
ATOM   3984  C CA  . ILE B 1 249 ? -25.192 19.154  19.755 1.00 27.94  ? 451 ILE B CA  1 
ATOM   3985  C C   . ILE B 1 249 ? -24.631 20.544  19.564 1.00 29.60  ? 451 ILE B C   1 
ATOM   3986  O O   . ILE B 1 249 ? -25.050 21.480  20.226 1.00 30.13  ? 451 ILE B O   1 
ATOM   3987  C CB  . ILE B 1 249 ? -26.531 19.053  18.992 1.00 26.03  ? 451 ILE B CB  1 
ATOM   3988  C CG1 . ILE B 1 249 ? -27.597 19.932  19.638 1.00 26.03  ? 451 ILE B CG1 1 
ATOM   3989  C CG2 . ILE B 1 249 ? -26.996 17.611  18.895 1.00 26.03  ? 451 ILE B CG2 1 
ATOM   3990  C CD1 . ILE B 1 249 ? -28.887 19.976  18.858 1.00 26.03  ? 451 ILE B CD1 1 
ATOM   3991  N N   . ASN B 1 250 ? -23.677 20.679  18.657 1.00 32.46  ? 452 ASN B N   1 
ATOM   3992  C CA  . ASN B 1 250 ? -23.062 21.969  18.419 1.00 34.83  ? 452 ASN B CA  1 
ATOM   3993  C C   . ASN B 1 250 ? -24.072 22.965  17.906 1.00 36.31  ? 452 ASN B C   1 
ATOM   3994  O O   . ASN B 1 250 ? -24.102 24.110  18.342 1.00 36.46  ? 452 ASN B O   1 
ATOM   3995  C CB  . ASN B 1 250 ? -21.951 21.827  17.384 1.00 32.47  ? 452 ASN B CB  1 
ATOM   3996  C CG  . ASN B 1 250 ? -20.748 21.081  17.916 1.00 34.67  ? 452 ASN B CG  1 
ATOM   3997  O OD1 . ASN B 1 250 ? -20.328 20.076  17.347 1.00 36.15  ? 452 ASN B OD1 1 
ATOM   3998  N ND2 . ASN B 1 250 ? -20.182 21.574  19.009 1.00 35.99  ? 452 ASN B ND2 1 
ATOM   3999  N N   . GLY B 1 251 ? -24.952 22.499  17.030 1.00 36.95  ? 453 GLY B N   1 
ATOM   4000  C CA  . GLY B 1 251 ? -25.987 23.344  16.469 1.00 39.30  ? 453 GLY B CA  1 
ATOM   4001  C C   . GLY B 1 251 ? -26.909 22.565  15.557 1.00 41.31  ? 453 GLY B C   1 
ATOM   4002  O O   . GLY B 1 251 ? -26.860 21.343  15.517 1.00 42.30  ? 453 GLY B O   1 
ATOM   4003  N N   . SER B 1 252 ? -27.761 23.274  14.831 1.00 47.22  ? 454 SER B N   1 
ATOM   4004  C CA  . SER B 1 252 ? -28.690 22.639  13.907 1.00 47.72  ? 454 SER B CA  1 
ATOM   4005  C C   . SER B 1 252 ? -27.968 22.090  12.688 1.00 46.97  ? 454 SER B C   1 
ATOM   4006  O O   . SER B 1 252 ? -26.919 22.594  12.298 1.00 46.45  ? 454 SER B O   1 
ATOM   4007  C CB  . SER B 1 252 ? -29.776 23.617  13.468 1.00 47.99  ? 454 SER B CB  1 
ATOM   4008  O OG  . SER B 1 252 ? -30.645 23.005  12.531 1.00 49.99  ? 454 SER B OG  1 
ATOM   4009  N N   . GLY B 1 253 ? -28.541 21.058  12.084 1.00 49.04  ? 455 GLY B N   1 
ATOM   4010  C CA  . GLY B 1 253 ? -27.957 20.442  10.911 1.00 48.45  ? 455 GLY B CA  1 
ATOM   4011  C C   . GLY B 1 253 ? -27.542 19.008  11.153 1.00 48.29  ? 455 GLY B C   1 
ATOM   4012  O O   . GLY B 1 253 ? -27.516 18.543  12.286 1.00 48.06  ? 455 GLY B O   1 
ATOM   4013  N N   . GLN B 1 254 ? -27.227 18.305  10.073 1.00 50.58  ? 456 GLN B N   1 
ATOM   4014  C CA  . GLN B 1 254 ? -26.821 16.910  10.147 1.00 51.01  ? 456 GLN B CA  1 
ATOM   4015  C C   . GLN B 1 254 ? -25.460 16.716  10.788 1.00 49.30  ? 456 GLN B C   1 
ATOM   4016  O O   . GLN B 1 254 ? -24.568 17.543  10.633 1.00 49.45  ? 456 GLN B O   1 
ATOM   4017  C CB  . GLN B 1 254 ? -26.797 16.292  8.753  1.00 51.20  ? 456 GLN B CB  1 
ATOM   4018  C CG  . GLN B 1 254 ? -28.128 16.330  8.031  1.00 56.96  ? 456 GLN B CG  1 
ATOM   4019  C CD  . GLN B 1 254 ? -29.164 15.453  8.691  1.00 60.32  ? 456 GLN B CD  1 
ATOM   4020  O OE1 . GLN B 1 254 ? -29.568 14.433  8.138  1.00 61.23  ? 456 GLN B OE1 1 
ATOM   4021  N NE2 . GLN B 1 254 ? -29.595 15.839  9.885  1.00 61.47  ? 456 GLN B NE2 1 
ATOM   4022  N N   . ASN B 1 255 ? -25.338 15.633  11.542 1.00 41.86  ? 457 ASN B N   1 
ATOM   4023  C CA  . ASN B 1 255 ? -24.094 15.231  12.186 1.00 40.12  ? 457 ASN B CA  1 
ATOM   4024  C C   . ASN B 1 255 ? -23.459 16.267  13.102 1.00 38.18  ? 457 ASN B C   1 
ATOM   4025  O O   . ASN B 1 255 ? -22.240 16.368  13.180 1.00 37.27  ? 457 ASN B O   1 
ATOM   4026  C CB  . ASN B 1 255 ? -23.091 14.735  11.143 1.00 37.99  ? 457 ASN B CB  1 
ATOM   4027  C CG  . ASN B 1 255 ? -23.689 13.694  10.225 1.00 39.27  ? 457 ASN B CG  1 
ATOM   4028  O OD1 . ASN B 1 255 ? -24.291 12.728  10.681 1.00 40.07  ? 457 ASN B OD1 1 
ATOM   4029  N ND2 . ASN B 1 255 ? -23.535 13.891  8.923  1.00 40.01  ? 457 ASN B ND2 1 
ATOM   4030  N N   . GLN B 1 256 ? -24.280 17.039  13.794 1.00 37.45  ? 458 GLN B N   1 
ATOM   4031  C CA  . GLN B 1 256 ? -23.773 18.048  14.708 1.00 35.69  ? 458 GLN B CA  1 
ATOM   4032  C C   . GLN B 1 256 ? -23.845 17.491  16.113 1.00 33.86  ? 458 GLN B C   1 
ATOM   4033  O O   . GLN B 1 256 ? -24.670 17.916  16.908 1.00 33.78  ? 458 GLN B O   1 
ATOM   4034  C CB  . GLN B 1 256 ? -24.611 19.322  14.613 1.00 37.57  ? 458 GLN B CB  1 
ATOM   4035  C CG  . GLN B 1 256 ? -24.406 20.114  13.334 1.00 40.17  ? 458 GLN B CG  1 
ATOM   4036  C CD  . GLN B 1 256 ? -22.977 20.579  13.169 1.00 42.56  ? 458 GLN B CD  1 
ATOM   4037  O OE1 . GLN B 1 256 ? -22.592 21.082  12.116 1.00 43.75  ? 458 GLN B OE1 1 
ATOM   4038  N NE2 . GLN B 1 256 ? -22.180 20.411  14.213 1.00 43.89  ? 458 GLN B NE2 1 
ATOM   4039  N N   . GLN B 1 257 ? -22.975 16.541  16.423 1.00 29.22  ? 459 GLN B N   1 
ATOM   4040  C CA  . GLN B 1 257 ? -22.975 15.907  17.733 1.00 27.31  ? 459 GLN B CA  1 
ATOM   4041  C C   . GLN B 1 257 ? -21.762 16.306  18.543 1.00 26.51  ? 459 GLN B C   1 
ATOM   4042  O O   . GLN B 1 257 ? -20.657 16.328  18.028 1.00 26.78  ? 459 GLN B O   1 
ATOM   4043  C CB  . GLN B 1 257 ? -23.016 14.393  17.572 1.00 23.81  ? 459 GLN B CB  1 
ATOM   4044  C CG  . GLN B 1 257 ? -24.370 13.862  17.151 1.00 24.66  ? 459 GLN B CG  1 
ATOM   4045  C CD  . GLN B 1 257 ? -24.276 12.890  16.001 1.00 24.03  ? 459 GLN B CD  1 
ATOM   4046  O OE1 . GLN B 1 257 ? -23.410 13.014  15.146 1.00 24.06  ? 459 GLN B OE1 1 
ATOM   4047  N NE2 . GLN B 1 257 ? -25.173 11.925  15.968 1.00 22.98  ? 459 GLN B NE2 1 
ATOM   4048  N N   . THR B 1 258 ? -21.972 16.658  19.804 1.00 23.17  ? 460 THR B N   1 
ATOM   4049  C CA  . THR B 1 258 ? -20.870 17.063  20.666 1.00 23.07  ? 460 THR B CA  1 
ATOM   4050  C C   . THR B 1 258 ? -21.189 16.887  22.136 1.00 21.21  ? 460 THR B C   1 
ATOM   4051  O O   . THR B 1 258 ? -22.332 16.664  22.501 1.00 21.56  ? 460 THR B O   1 
ATOM   4052  C CB  . THR B 1 258 ? -20.523 18.539  20.460 1.00 23.06  ? 460 THR B CB  1 
ATOM   4053  O OG1 . THR B 1 258 ? -19.277 18.822  21.097 1.00 22.69  ? 460 THR B OG1 1 
ATOM   4054  C CG2 . THR B 1 258 ? -21.590 19.411  21.077 1.00 25.19  ? 460 THR B CG2 1 
ATOM   4055  N N   . LEU B 1 259 ? -20.164 16.933  22.976 1.00 19.55  ? 461 LEU B N   1 
ATOM   4056  C CA  . LEU B 1 259 ? -20.368 16.860  24.412 1.00 16.75  ? 461 LEU B CA  1 
ATOM   4057  C C   . LEU B 1 259 ? -19.728 18.101  25.034 1.00 16.89  ? 461 LEU B C   1 
ATOM   4058  O O   . LEU B 1 259 ? -18.532 18.313  24.903 1.00 18.18  ? 461 LEU B O   1 
ATOM   4059  C CB  . LEU B 1 259 ? -19.757 15.580  24.983 1.00 18.61  ? 461 LEU B CB  1 
ATOM   4060  C CG  . LEU B 1 259 ? -20.390 14.248  24.563 1.00 16.47  ? 461 LEU B CG  1 
ATOM   4061  C CD1 . LEU B 1 259 ? -19.540 13.072  25.008 1.00 14.75  ? 461 LEU B CD1 1 
ATOM   4062  C CD2 . LEU B 1 259 ? -21.816 14.099  25.073 1.00 14.67  ? 461 LEU B CD2 1 
ATOM   4063  N N   . LYS B 1 260 ? -20.530 18.920  25.708 1.00 18.73  ? 462 LYS B N   1 
ATOM   4064  C CA  . LYS B 1 260 ? -20.042 20.141  26.346 1.00 18.16  ? 462 LYS B CA  1 
ATOM   4065  C C   . LYS B 1 260 ? -20.552 20.230  27.767 1.00 17.21  ? 462 LYS B C   1 
ATOM   4066  O O   . LYS B 1 260 ? -21.717 19.975  28.023 1.00 16.73  ? 462 LYS B O   1 
ATOM   4067  C CB  . LYS B 1 260 ? -20.477 21.373  25.566 1.00 16.82  ? 462 LYS B CB  1 
ATOM   4068  C CG  . LYS B 1 260 ? -20.090 21.351  24.104 1.00 18.59  ? 462 LYS B CG  1 
ATOM   4069  C CD  . LYS B 1 260 ? -18.616 21.613  23.914 1.00 19.39  ? 462 LYS B CD  1 
ATOM   4070  C CE  . LYS B 1 260 ? -18.303 21.767  22.442 1.00 21.55  ? 462 LYS B CE  1 
ATOM   4071  N NZ  . LYS B 1 260 ? -16.939 22.315  22.234 1.00 23.22  ? 462 LYS B NZ  1 
ATOM   4072  N N   . PHE B 1 261 ? -19.678 20.607  28.689 1.00 19.29  ? 463 PHE B N   1 
ATOM   4073  C CA  . PHE B 1 261 ? -20.037 20.689  30.098 1.00 17.92  ? 463 PHE B CA  1 
ATOM   4074  C C   . PHE B 1 261 ? -19.980 22.107  30.648 1.00 17.68  ? 463 PHE B C   1 
ATOM   4075  O O   . PHE B 1 261 ? -19.141 22.899  30.238 1.00 18.02  ? 463 PHE B O   1 
ATOM   4076  C CB  . PHE B 1 261 ? -19.143 19.738  30.892 1.00 15.45  ? 463 PHE B CB  1 
ATOM   4077  C CG  . PHE B 1 261 ? -19.063 18.371  30.288 1.00 13.93  ? 463 PHE B CG  1 
ATOM   4078  C CD1 . PHE B 1 261 ? -19.799 17.329  30.802 1.00 13.01  ? 463 PHE B CD1 1 
ATOM   4079  C CD2 . PHE B 1 261 ? -18.281 18.140  29.178 1.00 13.70  ? 463 PHE B CD2 1 
ATOM   4080  C CE1 . PHE B 1 261 ? -19.745 16.080  30.230 1.00 11.91  ? 463 PHE B CE1 1 
ATOM   4081  C CE2 . PHE B 1 261 ? -18.225 16.896  28.598 1.00 12.80  ? 463 PHE B CE2 1 
ATOM   4082  C CZ  . PHE B 1 261 ? -18.955 15.862  29.127 1.00 11.94  ? 463 PHE B CZ  1 
ATOM   4083  N N   . SER B 1 262 ? -20.886 22.418  31.571 1.00 17.36  ? 464 SER B N   1 
ATOM   4084  C CA  . SER B 1 262 ? -20.960 23.735  32.184 1.00 17.86  ? 464 SER B CA  1 
ATOM   4085  C C   . SER B 1 262 ? -20.950 23.589  33.698 1.00 18.00  ? 464 SER B C   1 
ATOM   4086  O O   . SER B 1 262 ? -21.271 22.530  34.238 1.00 17.91  ? 464 SER B O   1 
ATOM   4087  C CB  . SER B 1 262 ? -22.210 24.490  31.727 1.00 18.77  ? 464 SER B CB  1 
ATOM   4088  O OG  . SER B 1 262 ? -22.171 24.742  30.335 1.00 19.02  ? 464 SER B OG  1 
ATOM   4089  N N   . VAL B 1 263 ? -20.558 24.665  34.383 1.00 19.29  ? 465 VAL B N   1 
ATOM   4090  C CA  . VAL B 1 263 ? -20.611 24.680  35.839 1.00 20.53  ? 465 VAL B CA  1 
ATOM   4091  C C   . VAL B 1 263 ? -22.057 24.789  36.297 1.00 21.21  ? 465 VAL B C   1 
ATOM   4092  O O   . VAL B 1 263 ? -22.814 25.650  35.832 1.00 21.50  ? 465 VAL B O   1 
ATOM   4093  C CB  . VAL B 1 263 ? -19.777 25.839  36.414 1.00 21.82  ? 465 VAL B CB  1 
ATOM   4094  C CG1 . VAL B 1 263 ? -19.949 25.915  37.917 1.00 22.07  ? 465 VAL B CG1 1 
ATOM   4095  C CG2 . VAL B 1 263 ? -18.323 25.666  36.085 1.00 22.43  ? 465 VAL B CG2 1 
ATOM   4096  N N   . ALA B 1 264 ? -22.448 23.914  37.215 1.00 22.24  ? 466 ALA B N   1 
ATOM   4097  C CA  . ALA B 1 264 ? -23.747 24.023  37.859 1.00 23.46  ? 466 ALA B CA  1 
ATOM   4098  C C   . ALA B 1 264 ? -23.675 25.085  38.946 1.00 24.93  ? 466 ALA B C   1 
ATOM   4099  O O   . ALA B 1 264 ? -22.806 25.030  39.820 1.00 25.39  ? 466 ALA B O   1 
ATOM   4100  C CB  . ALA B 1 264 ? -24.168 22.680  38.448 1.00 22.13  ? 466 ALA B CB  1 
ATOM   4101  N N   . GLY B 1 265 ? -24.597 26.042  38.907 1.00 29.91  ? 467 GLY B N   1 
ATOM   4102  C CA  . GLY B 1 265 ? -24.500 27.190  39.772 1.00 30.75  ? 467 GLY B CA  1 
ATOM   4103  C C   . GLY B 1 265 ? -25.783 27.979  39.912 1.00 31.01  ? 467 GLY B C   1 
ATOM   4104  O O   . GLY B 1 265 ? -26.873 27.519  39.565 1.00 30.76  ? 467 GLY B O   1 
ATOM   4105  N N   . PRO B 1 266 ? -25.664 29.194  40.449 1.00 34.67  ? 468 PRO B N   1 
ATOM   4106  C CA  . PRO B 1 266 ? -26.857 30.002  40.742 1.00 35.06  ? 468 PRO B CA  1 
ATOM   4107  C C   . PRO B 1 266 ? -27.738 30.274  39.539 1.00 35.66  ? 468 PRO B C   1 
ATOM   4108  O O   . PRO B 1 266 ? -28.961 30.375  39.696 1.00 35.53  ? 468 PRO B O   1 
ATOM   4109  C CB  . PRO B 1 266 ? -26.258 31.301  41.295 1.00 36.07  ? 468 PRO B CB  1 
ATOM   4110  C CG  . PRO B 1 266 ? -24.935 30.900  41.832 1.00 35.99  ? 468 PRO B CG  1 
ATOM   4111  C CD  . PRO B 1 266 ? -24.430 29.852  40.901 1.00 36.36  ? 468 PRO B CD  1 
ATOM   4112  N N   . SER B 1 267 ? -27.160 30.411  38.344 1.00 34.53  ? 469 SER B N   1 
ATOM   4113  C CA  . SER B 1 267 ? -27.976 30.689  37.168 1.00 35.31  ? 469 SER B CA  1 
ATOM   4114  C C   . SER B 1 267 ? -28.939 29.548  36.873 1.00 35.27  ? 469 SER B C   1 
ATOM   4115  O O   . SER B 1 267 ? -30.147 29.777  36.749 1.00 35.47  ? 469 SER B O   1 
ATOM   4116  C CB  . SER B 1 267 ? -27.086 30.958  35.958 1.00 37.61  ? 469 SER B CB  1 
ATOM   4117  O OG  . SER B 1 267 ? -26.341 29.806  35.615 1.00 42.15  ? 469 SER B OG  1 
ATOM   4118  N N   . ASN B 1 268 ? -28.437 28.323  36.765 1.00 34.81  ? 470 ASN B N   1 
ATOM   4119  C CA  . ASN B 1 268 ? -29.270 27.150  36.516 1.00 33.53  ? 470 ASN B CA  1 
ATOM   4120  C C   . ASN B 1 268 ? -29.206 26.277  37.764 1.00 32.07  ? 470 ASN B C   1 
ATOM   4121  O O   . ASN B 1 268 ? -28.206 25.595  38.002 1.00 30.94  ? 470 ASN B O   1 
ATOM   4122  C CB  . ASN B 1 268 ? -28.787 26.415  35.268 1.00 33.46  ? 470 ASN B CB  1 
ATOM   4123  C CG  . ASN B 1 268 ? -29.751 25.345  34.801 1.00 36.10  ? 470 ASN B CG  1 
ATOM   4124  O OD1 . ASN B 1 268 ? -30.948 25.403  35.076 1.00 36.94  ? 470 ASN B OD1 1 
ATOM   4125  N ND2 . ASN B 1 268 ? -29.238 24.384  34.049 1.00 36.93  ? 470 ASN B ND2 1 
ATOM   4126  N N   . MET B 1 269 ? -30.280 26.287  38.552 1.00 32.61  ? 471 MET B N   1 
ATOM   4127  C CA  . MET B 1 269 ? -30.293 25.589  39.829 1.00 32.39  ? 471 MET B CA  1 
ATOM   4128  C C   . MET B 1 269 ? -30.879 24.189  39.758 1.00 31.19  ? 471 MET B C   1 
ATOM   4129  O O   . MET B 1 269 ? -30.731 23.430  40.721 1.00 31.86  ? 471 MET B O   1 
ATOM   4130  C CB  . MET B 1 269 ? -31.072 26.397  40.869 1.00 34.56  ? 471 MET B CB  1 
ATOM   4131  C CG  . MET B 1 269 ? -30.397 27.681  41.283 1.00 37.31  ? 471 MET B CG  1 
ATOM   4132  S SD  . MET B 1 269 ? -31.337 28.598  42.512 1.00 39.21  ? 471 MET B SD  1 
ATOM   4133  C CE  . MET B 1 269 ? -30.238 29.981  42.780 1.00 39.36  ? 471 MET B CE  1 
ATOM   4134  N N   . ALA B 1 270 ? -31.519 23.818  38.650 1.00 32.03  ? 472 ALA B N   1 
ATOM   4135  C CA  . ALA B 1 270 ? -32.209 22.536  38.602 1.00 30.32  ? 472 ALA B CA  1 
ATOM   4136  C C   . ALA B 1 270 ? -31.286 21.397  38.199 1.00 29.38  ? 472 ALA B C   1 
ATOM   4137  O O   . ALA B 1 270 ? -31.649 20.230  38.357 1.00 29.22  ? 472 ALA B O   1 
ATOM   4138  C CB  . ALA B 1 270 ? -33.394 22.612  37.640 1.00 30.84  ? 472 ALA B CB  1 
ATOM   4139  N N   . VAL B 1 271 ? -30.098 21.708  37.680 1.00 30.66  ? 473 VAL B N   1 
ATOM   4140  C CA  . VAL B 1 271 ? -29.153 20.684  37.257 1.00 29.51  ? 473 VAL B CA  1 
ATOM   4141  C C   . VAL B 1 271 ? -28.085 20.401  38.301 1.00 28.00  ? 473 VAL B C   1 
ATOM   4142  O O   . VAL B 1 271 ? -27.255 19.506  38.095 1.00 27.50  ? 473 VAL B O   1 
ATOM   4143  C CB  . VAL B 1 271 ? -28.496 21.072  35.920 1.00 24.16  ? 473 VAL B CB  1 
ATOM   4144  C CG1 . VAL B 1 271 ? -29.546 21.177  34.838 1.00 28.51  ? 473 VAL B CG1 1 
ATOM   4145  C CG2 . VAL B 1 271 ? -27.734 22.374  36.071 1.00 24.76  ? 473 VAL B CG2 1 
ATOM   4146  N N   . GLN B 1 272 ? -28.080 21.127  39.414 1.00 27.64  ? 474 GLN B N   1 
ATOM   4147  C CA  . GLN B 1 272 ? -27.033 20.952  40.408 1.00 26.21  ? 474 GLN B CA  1 
ATOM   4148  C C   . GLN B 1 272 ? -27.140 19.596  41.090 1.00 25.75  ? 474 GLN B C   1 
ATOM   4149  O O   . GLN B 1 272 ? -28.193 18.957  41.095 1.00 26.25  ? 474 GLN B O   1 
ATOM   4150  C CB  . GLN B 1 272 ? -27.101 22.040  41.473 1.00 25.58  ? 474 GLN B CB  1 
ATOM   4151  C CG  . GLN B 1 272 ? -26.760 23.427  41.007 1.00 28.62  ? 474 GLN B CG  1 
ATOM   4152  C CD  . GLN B 1 272 ? -26.759 24.399  42.158 1.00 30.25  ? 474 GLN B CD  1 
ATOM   4153  O OE1 . GLN B 1 272 ? -27.377 24.145  43.186 1.00 31.49  ? 474 GLN B OE1 1 
ATOM   4154  N NE2 . GLN B 1 272 ? -26.055 25.508  42.002 1.00 31.93  ? 474 GLN B NE2 1 
ATOM   4155  N N   . GLY B 1 273 ? -26.029 19.165  41.678 1.00 22.92  ? 475 GLY B N   1 
ATOM   4156  C CA  . GLY B 1 273 ? -26.057 17.971  42.497 1.00 21.78  ? 475 GLY B CA  1 
ATOM   4157  C C   . GLY B 1 273 ? -26.785 18.228  43.804 1.00 22.54  ? 475 GLY B C   1 
ATOM   4158  O O   . GLY B 1 273 ? -26.724 19.320  44.370 1.00 22.99  ? 475 GLY B O   1 
ATOM   4159  N N   . ARG B 1 274 ? -27.490 17.208  44.282 1.00 23.02  ? 476 ARG B N   1 
ATOM   4160  C CA  . ARG B 1 274 ? -28.236 17.303  45.526 1.00 22.77  ? 476 ARG B CA  1 
ATOM   4161  C C   . ARG B 1 274 ? -28.025 16.053  46.366 1.00 22.51  ? 476 ARG B C   1 
ATOM   4162  O O   . ARG B 1 274 ? -27.916 14.942  45.846 1.00 23.60  ? 476 ARG B O   1 
ATOM   4163  C CB  . ARG B 1 274 ? -29.726 17.522  45.271 1.00 21.23  ? 476 ARG B CB  1 
ATOM   4164  C CG  . ARG B 1 274 ? -30.031 18.896  44.726 1.00 22.78  ? 476 ARG B CG  1 
ATOM   4165  C CD  . ARG B 1 274 ? -31.501 19.102  44.469 1.00 24.13  ? 476 ARG B CD  1 
ATOM   4166  N NE  . ARG B 1 274 ? -31.768 20.470  44.040 1.00 28.36  ? 476 ARG B NE  1 
ATOM   4167  C CZ  . ARG B 1 274 ? -31.625 20.905  42.795 1.00 29.23  ? 476 ARG B CZ  1 
ATOM   4168  N NH1 . ARG B 1 274 ? -31.216 20.078  41.844 1.00 32.04  ? 476 ARG B NH1 1 
ATOM   4169  N NH2 . ARG B 1 274 ? -31.890 22.167  42.501 1.00 31.33  ? 476 ARG B NH2 1 
ATOM   4170  N N   . ASN B 1 275 ? -27.954 16.259  47.677 1.00 22.94  ? 477 ASN B N   1 
ATOM   4171  C CA  . ASN B 1 275 ? -27.773 15.171  48.624 1.00 22.31  ? 477 ASN B CA  1 
ATOM   4172  C C   . ASN B 1 275 ? -29.061 14.446  48.983 1.00 21.95  ? 477 ASN B C   1 
ATOM   4173  O O   . ASN B 1 275 ? -28.995 13.305  49.453 1.00 20.97  ? 477 ASN B O   1 
ATOM   4174  C CB  . ASN B 1 275 ? -27.115 15.696  49.902 1.00 21.35  ? 477 ASN B CB  1 
ATOM   4175  C CG  . ASN B 1 275 ? -25.629 15.909  49.742 1.00 22.87  ? 477 ASN B CG  1 
ATOM   4176  O OD1 . ASN B 1 275 ? -24.981 15.226  48.956 1.00 25.19  ? 477 ASN B OD1 1 
ATOM   4177  N ND2 . ASN B 1 275 ? -25.084 16.872  50.467 1.00 23.21  ? 477 ASN B ND2 1 
ATOM   4178  N N   . TYR B 1 276 ? -30.225 15.058  48.785 1.00 20.77  ? 478 TYR B N   1 
ATOM   4179  C CA  . TYR B 1 276 ? -31.466 14.442  49.228 1.00 21.83  ? 478 TYR B CA  1 
ATOM   4180  C C   . TYR B 1 276 ? -32.585 14.719  48.236 1.00 22.91  ? 478 TYR B C   1 
ATOM   4181  O O   . TYR B 1 276 ? -32.506 15.659  47.442 1.00 25.04  ? 478 TYR B O   1 
ATOM   4182  C CB  . TYR B 1 276 ? -31.846 14.932  50.627 1.00 19.82  ? 478 TYR B CB  1 
ATOM   4183  C CG  . TYR B 1 276 ? -30.803 14.578  51.663 1.00 22.03  ? 478 TYR B CG  1 
ATOM   4184  C CD1 . TYR B 1 276 ? -30.784 13.324  52.249 1.00 22.53  ? 478 TYR B CD1 1 
ATOM   4185  C CD2 . TYR B 1 276 ? -29.834 15.493  52.045 1.00 21.22  ? 478 TYR B CD2 1 
ATOM   4186  C CE1 . TYR B 1 276 ? -29.832 12.990  53.183 1.00 22.77  ? 478 TYR B CE1 1 
ATOM   4187  C CE2 . TYR B 1 276 ? -28.876 15.165  52.982 1.00 23.07  ? 478 TYR B CE2 1 
ATOM   4188  C CZ  . TYR B 1 276 ? -28.882 13.911  53.548 1.00 23.89  ? 478 TYR B CZ  1 
ATOM   4189  O OH  . TYR B 1 276 ? -27.935 13.570  54.485 1.00 25.44  ? 478 TYR B OH  1 
ATOM   4190  N N   . ILE B 1 277 ? -33.618 13.888  48.291 1.00 23.90  ? 479 ILE B N   1 
ATOM   4191  C CA  . ILE B 1 277 ? -34.694 13.870  47.303 1.00 23.29  ? 479 ILE B CA  1 
ATOM   4192  C C   . ILE B 1 277 ? -36.013 13.733  48.051 1.00 24.45  ? 479 ILE B C   1 
ATOM   4193  O O   . ILE B 1 277 ? -36.048 13.236  49.189 1.00 24.82  ? 479 ILE B O   1 
ATOM   4194  C CB  . ILE B 1 277 ? -34.498 12.739  46.267 1.00 23.86  ? 479 ILE B CB  1 
ATOM   4195  C CG1 . ILE B 1 277 ? -34.361 11.391  46.974 1.00 22.23  ? 479 ILE B CG1 1 
ATOM   4196  C CG2 . ILE B 1 277 ? -33.303 13.018  45.380 1.00 22.68  ? 479 ILE B CG2 1 
ATOM   4197  C CD1 . ILE B 1 277 ? -34.314 10.217  46.038 1.00 20.74  ? 479 ILE B CD1 1 
ATOM   4198  N N   . PRO B 1 278 ? -37.120 14.164  47.448 1.00 27.42  ? 480 PRO B N   1 
ATOM   4199  C CA  . PRO B 1 278 ? -38.397 14.178  48.168 1.00 27.86  ? 480 PRO B CA  1 
ATOM   4200  C C   . PRO B 1 278 ? -38.981 12.787  48.345 1.00 28.54  ? 480 PRO B C   1 
ATOM   4201  O O   . PRO B 1 278 ? -38.588 11.821  47.689 1.00 28.02  ? 480 PRO B O   1 
ATOM   4202  C CB  . PRO B 1 278 ? -39.294 15.041  47.277 1.00 26.87  ? 480 PRO B CB  1 
ATOM   4203  C CG  . PRO B 1 278 ? -38.750 14.843  45.932 1.00 27.32  ? 480 PRO B CG  1 
ATOM   4204  C CD  . PRO B 1 278 ? -37.264 14.743  46.104 1.00 26.10  ? 480 PRO B CD  1 
ATOM   4205  N N   . GLY B 1 279 ? -39.960 12.709  49.244 1.00 27.44  ? 481 GLY B N   1 
ATOM   4206  C CA  . GLY B 1 279 ? -40.533 11.456  49.674 1.00 28.51  ? 481 GLY B CA  1 
ATOM   4207  C C   . GLY B 1 279 ? -41.318 10.712  48.613 1.00 29.38  ? 481 GLY B C   1 
ATOM   4208  O O   . GLY B 1 279 ? -41.475 11.165  47.476 1.00 29.93  ? 481 GLY B O   1 
ATOM   4209  N N   . PRO B 1 280 ? -41.825 9.540   48.980 1.00 31.18  ? 482 PRO B N   1 
ATOM   4210  C CA  . PRO B 1 280 ? -42.530 8.689   48.017 1.00 31.73  ? 482 PRO B CA  1 
ATOM   4211  C C   . PRO B 1 280 ? -43.897 9.244   47.647 1.00 32.73  ? 482 PRO B C   1 
ATOM   4212  O O   . PRO B 1 280 ? -44.475 10.077  48.346 1.00 32.83  ? 482 PRO B O   1 
ATOM   4213  C CB  . PRO B 1 280 ? -42.667 7.363   48.768 1.00 30.34  ? 482 PRO B CB  1 
ATOM   4214  C CG  . PRO B 1 280 ? -42.703 7.769   50.194 1.00 30.21  ? 482 PRO B CG  1 
ATOM   4215  C CD  . PRO B 1 280 ? -41.749 8.916   50.310 1.00 29.90  ? 482 PRO B CD  1 
ATOM   4216  N N   . SER B 1 281 ? -44.417 8.746   46.527 1.00 31.64  ? 483 SER B N   1 
ATOM   4217  C CA  . SER B 1 281 ? -45.682 9.219   45.988 1.00 32.50  ? 483 SER B CA  1 
ATOM   4218  C C   . SER B 1 281 ? -46.487 8.051   45.440 1.00 31.92  ? 483 SER B C   1 
ATOM   4219  O O   . SER B 1 281 ? -45.934 7.097   44.889 1.00 32.36  ? 483 SER B O   1 
ATOM   4220  C CB  . SER B 1 281 ? -45.476 10.252  44.876 1.00 27.07  ? 483 SER B CB  1 
ATOM   4221  O OG  . SER B 1 281 ? -44.863 9.657   43.748 1.00 29.51  ? 483 SER B OG  1 
ATOM   4222  N N   . TYR B 1 282 ? -47.803 8.126   45.628 1.00 39.49  ? 484 TYR B N   1 
ATOM   4223  C CA  . TYR B 1 282 ? -48.756 7.213   45.001 1.00 37.52  ? 484 TYR B CA  1 
ATOM   4224  C C   . TYR B 1 282 ? -49.886 8.099   44.493 1.00 36.94  ? 484 TYR B C   1 
ATOM   4225  O O   . TYR B 1 282 ? -50.655 8.620   45.303 1.00 37.21  ? 484 TYR B O   1 
ATOM   4226  C CB  . TYR B 1 282 ? -49.247 6.198   46.032 1.00 39.37  ? 484 TYR B CB  1 
ATOM   4227  C CG  . TYR B 1 282 ? -50.130 5.080   45.541 1.00 38.31  ? 484 TYR B CG  1 
ATOM   4228  C CD1 . TYR B 1 282 ? -49.580 3.915   45.024 1.00 38.17  ? 484 TYR B CD1 1 
ATOM   4229  C CD2 . TYR B 1 282 ? -51.510 5.174   45.619 1.00 37.63  ? 484 TYR B CD2 1 
ATOM   4230  C CE1 . TYR B 1 282 ? -50.378 2.879   44.597 1.00 37.27  ? 484 TYR B CE1 1 
ATOM   4231  C CE2 . TYR B 1 282 ? -52.317 4.149   45.186 1.00 36.72  ? 484 TYR B CE2 1 
ATOM   4232  C CZ  . TYR B 1 282 ? -51.747 3.004   44.671 1.00 37.22  ? 484 TYR B CZ  1 
ATOM   4233  O OH  . TYR B 1 282 ? -52.551 1.977   44.238 1.00 36.91  ? 484 TYR B OH  1 
ATOM   4234  N N   . ARG B 1 283 ? -50.031 8.246   43.176 1.00 40.40  ? 485 ARG B N   1 
ATOM   4235  C CA  . ARG B 1 283 ? -50.760 9.410   42.676 1.00 39.89  ? 485 ARG B CA  1 
ATOM   4236  C C   . ARG B 1 283 ? -52.265 9.279   42.890 1.00 39.97  ? 485 ARG B C   1 
ATOM   4237  O O   . ARG B 1 283 ? -52.865 8.238   42.615 1.00 39.56  ? 485 ARG B O   1 
ATOM   4238  C CB  . ARG B 1 283 ? -50.492 9.667   41.189 1.00 36.99  ? 485 ARG B CB  1 
ATOM   4239  C CG  . ARG B 1 283 ? -51.174 10.975  40.769 1.00 38.59  ? 485 ARG B CG  1 
ATOM   4240  C CD  . ARG B 1 283 ? -51.258 11.306  39.286 1.00 38.03  ? 485 ARG B CD  1 
ATOM   4241  N NE  . ARG B 1 283 ? -50.003 11.650  38.634 1.00 38.70  ? 485 ARG B NE  1 
ATOM   4242  C CZ  . ARG B 1 283 ? -49.932 12.025  37.361 1.00 38.13  ? 485 ARG B CZ  1 
ATOM   4243  N NH1 . ARG B 1 283 ? -51.037 12.114  36.642 1.00 37.14  ? 485 ARG B NH1 1 
ATOM   4244  N NH2 . ARG B 1 283 ? -48.770 12.324  36.806 1.00 40.34  ? 485 ARG B NH2 1 
ATOM   4245  N N   . GLN B 1 284 ? -52.870 10.360  43.378 1.00 42.43  ? 486 GLN B N   1 
ATOM   4246  C CA  . GLN B 1 284 ? -54.312 10.529  43.473 1.00 42.98  ? 486 GLN B CA  1 
ATOM   4247  C C   . GLN B 1 284 ? -54.822 11.335  42.283 1.00 43.78  ? 486 GLN B C   1 
ATOM   4248  O O   . GLN B 1 284 ? -54.159 12.259  41.808 1.00 43.40  ? 486 GLN B O   1 
ATOM   4249  C CB  . GLN B 1 284 ? -54.694 11.251  44.768 1.00 42.34  ? 486 GLN B CB  1 
ATOM   4250  C CG  . GLN B 1 284 ? -54.422 10.492  46.051 1.00 44.22  ? 486 GLN B CG  1 
ATOM   4251  C CD  . GLN B 1 284 ? -55.234 9.224   46.161 1.00 46.08  ? 486 GLN B CD  1 
ATOM   4252  O OE1 . GLN B 1 284 ? -56.403 9.187   45.780 1.00 47.28  ? 486 GLN B OE1 1 
ATOM   4253  N NE2 . GLN B 1 284 ? -54.620 8.175   46.692 1.00 46.96  ? 486 GLN B NE2 1 
ATOM   4254  N N   . GLN B 1 285 ? -56.012 10.985  41.807 1.00 49.28  ? 487 GLN B N   1 
ATOM   4255  C CA  . GLN B 1 285 ? -56.653 11.761  40.755 1.00 49.34  ? 487 GLN B CA  1 
ATOM   4256  C C   . GLN B 1 285 ? -57.104 13.115  41.288 1.00 49.77  ? 487 GLN B C   1 
ATOM   4257  O O   . GLN B 1 285 ? -57.567 13.238  42.425 1.00 49.86  ? 487 GLN B O   1 
ATOM   4258  C CB  . GLN B 1 285 ? -57.844 10.999  40.176 1.00 50.34  ? 487 GLN B CB  1 
ATOM   4259  C CG  . GLN B 1 285 ? -58.572 11.728  39.063 1.00 50.25  ? 487 GLN B CG  1 
ATOM   4260  C CD  . GLN B 1 285 ? -57.687 12.002  37.869 1.00 50.78  ? 487 GLN B CD  1 
ATOM   4261  O OE1 . GLN B 1 285 ? -57.209 13.118  37.685 1.00 48.12  ? 487 GLN B OE1 1 
ATOM   4262  N NE2 . GLN B 1 285 ? -57.461 10.983  37.053 1.00 50.95  ? 487 GLN B NE2 1 
ATOM   4263  N N   . ARG B 1 286 ? -56.967 14.139  40.451 1.00 48.61  ? 488 ARG B N   1 
ATOM   4264  C CA  . ARG B 1 286 ? -57.203 15.518  40.856 1.00 48.56  ? 488 ARG B CA  1 
ATOM   4265  C C   . ARG B 1 286 ? -58.669 15.877  40.656 1.00 48.50  ? 488 ARG B C   1 
ATOM   4266  O O   . ARG B 1 286 ? -59.276 15.497  39.650 1.00 50.17  ? 488 ARG B O   1 
ATOM   4267  C CB  . ARG B 1 286 ? -56.318 16.479  40.065 1.00 44.21  ? 488 ARG B CB  1 
ATOM   4268  C CG  . ARG B 1 286 ? -56.376 17.899  40.578 1.00 45.31  ? 488 ARG B CG  1 
ATOM   4269  C CD  . ARG B 1 286 ? -55.557 18.850  39.736 1.00 47.63  ? 488 ARG B CD  1 
ATOM   4270  N NE  . ARG B 1 286 ? -56.119 18.998  38.401 1.00 50.77  ? 488 ARG B NE  1 
ATOM   4271  C CZ  . ARG B 1 286 ? -55.516 19.630  37.403 1.00 53.44  ? 488 ARG B CZ  1 
ATOM   4272  N NH1 . ARG B 1 286 ? -56.104 19.710  36.219 1.00 51.30  ? 488 ARG B NH1 1 
ATOM   4273  N NH2 . ARG B 1 286 ? -54.337 20.203  37.596 1.00 56.62  ? 488 ARG B NH2 1 
ATOM   4274  N N   . VAL B 1 287 ? -59.230 16.616  41.608 1.00 50.20  ? 489 VAL B N   1 
ATOM   4275  C CA  . VAL B 1 287 ? -60.618 17.052  41.551 1.00 49.79  ? 489 VAL B CA  1 
ATOM   4276  C C   . VAL B 1 287 ? -60.663 18.554  41.788 1.00 50.31  ? 489 VAL B C   1 
ATOM   4277  O O   . VAL B 1 287 ? -60.055 19.061  42.736 1.00 51.35  ? 489 VAL B O   1 
ATOM   4278  C CB  . VAL B 1 287 ? -61.493 16.309  42.583 1.00 53.02  ? 489 VAL B CB  1 
ATOM   4279  C CG1 . VAL B 1 287 ? -62.914 16.838  42.555 1.00 51.95  ? 489 VAL B CG1 1 
ATOM   4280  C CG2 . VAL B 1 287 ? -61.474 14.817  42.316 1.00 53.86  ? 489 VAL B CG2 1 
ATOM   4281  N N   . SER B 1 288 ? -61.377 19.265  40.923 1.00 52.25  ? 490 SER B N   1 
ATOM   4282  C CA  . SER B 1 288 ? -61.541 20.705  41.032 1.00 52.70  ? 490 SER B CA  1 
ATOM   4283  C C   . SER B 1 288 ? -62.821 21.043  41.783 1.00 53.60  ? 490 SER B C   1 
ATOM   4284  O O   . SER B 1 288 ? -63.880 20.462  41.535 1.00 52.18  ? 490 SER B O   1 
ATOM   4285  C CB  . SER B 1 288 ? -61.572 21.353  39.648 1.00 51.48  ? 490 SER B CB  1 
ATOM   4286  O OG  . SER B 1 288 ? -61.794 22.747  39.746 1.00 51.55  ? 490 SER B OG  1 
ATOM   4287  N N   . THR B 1 289 ? -62.716 21.995  42.710 1.00 51.35  ? 491 THR B N   1 
ATOM   4288  C CA  . THR B 1 289 ? -63.885 22.471  43.437 1.00 53.88  ? 491 THR B CA  1 
ATOM   4289  C C   . THR B 1 289 ? -64.928 23.099  42.525 1.00 55.71  ? 491 THR B C   1 
ATOM   4290  O O   . THR B 1 289 ? -66.109 23.123  42.887 1.00 56.81  ? 491 THR B O   1 
ATOM   4291  C CB  . THR B 1 289 ? -63.474 23.484  44.505 1.00 53.94  ? 491 THR B CB  1 
ATOM   4292  O OG1 . THR B 1 289 ? -62.819 24.596  43.883 1.00 57.34  ? 491 THR B OG1 1 
ATOM   4293  C CG2 . THR B 1 289 ? -62.531 22.842  45.508 1.00 52.83  ? 491 THR B CG2 1 
ATOM   4294  N N   . THR B 1 290 ? -64.524 23.603  41.361 1.00 59.14  ? 492 THR B N   1 
ATOM   4295  C CA  . THR B 1 290 ? -65.455 24.096  40.354 1.00 60.23  ? 492 THR B CA  1 
ATOM   4296  C C   . THR B 1 290 ? -65.920 22.900  39.534 1.00 59.96  ? 492 THR B C   1 
ATOM   4297  O O   . THR B 1 290 ? -65.111 22.245  38.871 1.00 60.08  ? 492 THR B O   1 
ATOM   4298  C CB  . THR B 1 290 ? -64.790 25.147  39.469 1.00 57.54  ? 492 THR B CB  1 
ATOM   4299  O OG1 . THR B 1 290 ? -64.377 26.259  40.273 1.00 59.90  ? 492 THR B OG1 1 
ATOM   4300  C CG2 . THR B 1 290 ? -65.751 25.628  38.399 1.00 57.38  ? 492 THR B CG2 1 
ATOM   4301  N N   . VAL B 1 291 ? -67.222 22.619  39.573 1.00 62.74  ? 493 VAL B N   1 
ATOM   4302  C CA  . VAL B 1 291 ? -67.714 21.373  38.996 1.00 62.51  ? 493 VAL B CA  1 
ATOM   4303  C C   . VAL B 1 291 ? -67.568 21.356  37.479 1.00 62.00  ? 493 VAL B C   1 
ATOM   4304  O O   . VAL B 1 291 ? -67.304 20.301  36.895 1.00 61.87  ? 493 VAL B O   1 
ATOM   4305  C CB  . VAL B 1 291 ? -69.171 21.125  39.420 1.00 61.08  ? 493 VAL B CB  1 
ATOM   4306  C CG1 . VAL B 1 291 ? -69.253 20.925  40.921 1.00 62.74  ? 493 VAL B CG1 1 
ATOM   4307  C CG2 . VAL B 1 291 ? -70.064 22.274  38.986 1.00 60.95  ? 493 VAL B CG2 1 
ATOM   4308  N N   . THR B 1 292 ? -67.716 22.504  36.818 1.00 64.56  ? 494 THR B N   1 
ATOM   4309  C CA  . THR B 1 292 ? -67.719 22.519  35.360 1.00 63.99  ? 494 THR B CA  1 
ATOM   4310  C C   . THR B 1 292 ? -66.364 22.156  34.773 1.00 63.77  ? 494 THR B C   1 
ATOM   4311  O O   . THR B 1 292 ? -66.303 21.700  33.626 1.00 63.88  ? 494 THR B O   1 
ATOM   4312  C CB  . THR B 1 292 ? -68.158 23.889  34.850 1.00 66.10  ? 494 THR B CB  1 
ATOM   4313  O OG1 . THR B 1 292 ? -67.278 24.896  35.366 1.00 66.36  ? 494 THR B OG1 1 
ATOM   4314  C CG2 . THR B 1 292 ? -69.580 24.183  35.296 1.00 65.14  ? 494 THR B CG2 1 
ATOM   4315  N N   . GLN B 1 293 ? -65.280 22.347  35.524 1.00 62.10  ? 495 GLN B N   1 
ATOM   4316  C CA  . GLN B 1 293 ? -63.963 21.948  35.050 1.00 61.26  ? 495 GLN B CA  1 
ATOM   4317  C C   . GLN B 1 293 ? -63.741 20.448  35.153 1.00 60.85  ? 495 GLN B C   1 
ATOM   4318  O O   . GLN B 1 293 ? -62.929 19.901  34.400 1.00 61.27  ? 495 GLN B O   1 
ATOM   4319  C CB  . GLN B 1 293 ? -62.877 22.691  35.829 1.00 55.80  ? 495 GLN B CB  1 
ATOM   4320  C CG  . GLN B 1 293 ? -62.861 24.186  35.579 1.00 58.28  ? 495 GLN B CG  1 
ATOM   4321  C CD  . GLN B 1 293 ? -61.841 24.908  36.432 1.00 60.15  ? 495 GLN B CD  1 
ATOM   4322  O OE1 . GLN B 1 293 ? -61.442 24.421  37.488 1.00 61.93  ? 495 GLN B OE1 1 
ATOM   4323  N NE2 . GLN B 1 293 ? -61.418 26.082  35.980 1.00 61.50  ? 495 GLN B NE2 1 
ATOM   4324  N N   . ASN B 1 294 ? -64.441 19.777  36.062 1.00 63.74  ? 496 ASN B N   1 
ATOM   4325  C CA  . ASN B 1 294 ? -64.377 18.331  36.166 1.00 63.06  ? 496 ASN B CA  1 
ATOM   4326  C C   . ASN B 1 294 ? -65.045 17.683  34.959 1.00 63.60  ? 496 ASN B C   1 
ATOM   4327  O O   . ASN B 1 294 ? -65.865 18.292  34.267 1.00 63.53  ? 496 ASN B O   1 
ATOM   4328  C CB  . ASN B 1 294 ? -65.049 17.856  37.454 1.00 60.91  ? 496 ASN B CB  1 
ATOM   4329  C CG  . ASN B 1 294 ? -64.270 18.240  38.692 1.00 60.94  ? 496 ASN B CG  1 
ATOM   4330  O OD1 . ASN B 1 294 ? -63.058 18.437  38.640 1.00 59.68  ? 496 ASN B OD1 1 
ATOM   4331  N ND2 . ASN B 1 294 ? -64.966 18.357  39.815 1.00 62.23  ? 496 ASN B ND2 1 
ATOM   4332  N N   . ASN B 1 295 ? -64.685 16.425  34.721 1.00 67.06  ? 497 ASN B N   1 
ATOM   4333  C CA  . ASN B 1 295 ? -65.218 15.647  33.611 1.00 67.82  ? 497 ASN B CA  1 
ATOM   4334  C C   . ASN B 1 295 ? -66.655 15.224  33.889 1.00 68.70  ? 497 ASN B C   1 
ATOM   4335  O O   . ASN B 1 295 ? -67.009 14.916  35.022 1.00 68.44  ? 497 ASN B O   1 
ATOM   4336  C CB  . ASN B 1 295 ? -64.342 14.414  33.382 1.00 64.24  ? 497 ASN B CB  1 
ATOM   4337  C CG  . ASN B 1 295 ? -64.690 13.670  32.109 1.00 65.47  ? 497 ASN B CG  1 
ATOM   4338  O OD1 . ASN B 1 295 ? -65.729 13.901  31.503 1.00 65.91  ? 497 ASN B OD1 1 
ATOM   4339  N ND2 . ASN B 1 295 ? -63.816 12.765  31.701 1.00 65.71  ? 497 ASN B ND2 1 
ATOM   4340  N N   . ASN B 1 296 ? -67.483 15.205  32.852 1.00 67.85  ? 498 ASN B N   1 
ATOM   4341  C CA  . ASN B 1 296 ? -68.876 14.815  33.006 1.00 69.00  ? 498 ASN B CA  1 
ATOM   4342  C C   . ASN B 1 296 ? -69.043 13.310  32.941 1.00 69.71  ? 498 ASN B C   1 
ATOM   4343  O O   . ASN B 1 296 ? -69.539 12.778  31.954 1.00 70.27  ? 498 ASN B O   1 
ATOM   4344  C CB  . ASN B 1 296 ? -69.745 15.459  31.928 1.00 72.84  ? 498 ASN B CB  1 
ATOM   4345  C CG  . ASN B 1 296 ? -71.227 15.224  32.156 1.00 72.95  ? 498 ASN B CG  1 
ATOM   4346  O OD1 . ASN B 1 296 ? -71.763 15.546  33.214 1.00 72.66  ? 498 ASN B OD1 1 
ATOM   4347  N ND2 . ASN B 1 296 ? -71.897 14.671  31.157 1.00 73.91  ? 498 ASN B ND2 1 
ATOM   4348  N N   . SER B 1 297 ? -68.606 12.628  33.991 1.00 65.83  ? 499 SER B N   1 
ATOM   4349  C CA  . SER B 1 297 ? -68.725 11.179  34.091 1.00 66.71  ? 499 SER B CA  1 
ATOM   4350  C C   . SER B 1 297 ? -68.633 10.787  35.558 1.00 66.86  ? 499 SER B C   1 
ATOM   4351  O O   . SER B 1 297 ? -68.241 11.596  36.391 1.00 66.54  ? 499 SER B O   1 
ATOM   4352  C CB  . SER B 1 297 ? -67.640 10.473  33.281 1.00 60.05  ? 499 SER B CB  1 
ATOM   4353  O OG  . SER B 1 297 ? -66.489 10.245  34.069 1.00 60.94  ? 499 SER B OG  1 
ATOM   4354  N N   . GLU B 1 298 ? -69.014 9.563   35.890 1.00 57.42  ? 500 GLU B N   1 
ATOM   4355  C CA  . GLU B 1 298 ? -68.910 9.135   37.275 1.00 57.93  ? 500 GLU B CA  1 
ATOM   4356  C C   . GLU B 1 298 ? -67.573 8.436   37.445 1.00 57.16  ? 500 GLU B C   1 
ATOM   4357  O O   . GLU B 1 298 ? -67.387 7.318   36.975 1.00 57.57  ? 500 GLU B O   1 
ATOM   4358  C CB  . GLU B 1 298 ? -70.044 8.181   37.623 1.00 53.93  ? 500 GLU B CB  1 
ATOM   4359  C CG  . GLU B 1 298 ? -69.826 7.439   38.924 1.00 58.00  ? 500 GLU B CG  1 
ATOM   4360  C CD  . GLU B 1 298 ? -69.863 8.360   40.121 1.00 60.36  ? 500 GLU B CD  1 
ATOM   4361  O OE1 . GLU B 1 298 ? -70.704 9.280   40.136 1.00 61.62  ? 500 GLU B OE1 1 
ATOM   4362  O OE2 . GLU B 1 298 ? -69.058 8.158   41.048 1.00 60.47  ? 500 GLU B OE2 1 
ATOM   4363  N N   . PHE B 1 299 ? -66.636 9.107   38.104 1.00 57.27  ? 501 PHE B N   1 
ATOM   4364  C CA  . PHE B 1 299 ? -65.306 8.548   38.313 1.00 56.20  ? 501 PHE B CA  1 
ATOM   4365  C C   . PHE B 1 299 ? -64.875 8.360   39.766 1.00 55.74  ? 501 PHE B C   1 
ATOM   4366  O O   . PHE B 1 299 ? -63.703 8.112   40.024 1.00 55.96  ? 501 PHE B O   1 
ATOM   4367  C CB  . PHE B 1 299 ? -64.256 9.375   37.565 1.00 58.35  ? 501 PHE B CB  1 
ATOM   4368  C CG  . PHE B 1 299 ? -64.151 10.793  38.038 1.00 57.52  ? 501 PHE B CG  1 
ATOM   4369  C CD1 . PHE B 1 299 ? -63.494 11.095  39.212 1.00 57.14  ? 501 PHE B CD1 1 
ATOM   4370  C CD2 . PHE B 1 299 ? -64.709 11.822  37.307 1.00 57.20  ? 501 PHE B CD2 1 
ATOM   4371  C CE1 . PHE B 1 299 ? -63.397 12.398  39.652 1.00 56.67  ? 501 PHE B CE1 1 
ATOM   4372  C CE2 . PHE B 1 299 ? -64.613 13.128  37.740 1.00 56.60  ? 501 PHE B CE2 1 
ATOM   4373  C CZ  . PHE B 1 299 ? -63.956 13.417  38.914 1.00 56.33  ? 501 PHE B CZ  1 
ATOM   4374  N N   . ALA B 1 300 ? -65.797 8.447   40.716 1.00 54.92  ? 502 ALA B N   1 
ATOM   4375  C CA  . ALA B 1 300 ? -65.393 8.321   42.111 1.00 53.97  ? 502 ALA B CA  1 
ATOM   4376  C C   . ALA B 1 300 ? -64.762 6.969   42.403 1.00 53.78  ? 502 ALA B C   1 
ATOM   4377  O O   . ALA B 1 300 ? -63.767 6.891   43.112 1.00 53.70  ? 502 ALA B O   1 
ATOM   4378  C CB  . ALA B 1 300 ? -66.568 8.570   43.040 1.00 54.27  ? 502 ALA B CB  1 
ATOM   4379  N N   . TRP B 1 301 ? -65.341 5.899   41.878 1.00 50.27  ? 503 TRP B N   1 
ATOM   4380  C CA  . TRP B 1 301 ? -64.755 4.587   42.092 1.00 50.81  ? 503 TRP B CA  1 
ATOM   4381  C C   . TRP B 1 301 ? -63.942 4.129   40.889 1.00 50.49  ? 503 TRP B C   1 
ATOM   4382  O O   . TRP B 1 301 ? -62.835 3.622   41.038 1.00 50.47  ? 503 TRP B O   1 
ATOM   4383  C CB  . TRP B 1 301 ? -65.816 3.546   42.432 1.00 47.65  ? 503 TRP B CB  1 
ATOM   4384  C CG  . TRP B 1 301 ? -65.208 2.219   42.717 1.00 50.92  ? 503 TRP B CG  1 
ATOM   4385  C CD1 . TRP B 1 301 ? -65.375 1.070   42.008 1.00 51.78  ? 503 TRP B CD1 1 
ATOM   4386  C CD2 . TRP B 1 301 ? -64.295 1.911   43.772 1.00 52.50  ? 503 TRP B CD2 1 
ATOM   4387  N NE1 . TRP B 1 301 ? -64.636 0.060   42.566 1.00 52.42  ? 503 TRP B NE1 1 
ATOM   4388  C CE2 . TRP B 1 301 ? -63.962 0.552   43.651 1.00 52.78  ? 503 TRP B CE2 1 
ATOM   4389  C CE3 . TRP B 1 301 ? -63.733 2.652   44.813 1.00 53.27  ? 503 TRP B CE3 1 
ATOM   4390  C CZ2 . TRP B 1 301 ? -63.094 -0.083  44.532 1.00 53.56  ? 503 TRP B CZ2 1 
ATOM   4391  C CZ3 . TRP B 1 301 ? -62.872 2.021   45.685 1.00 53.88  ? 503 TRP B CZ3 1 
ATOM   4392  C CH2 . TRP B 1 301 ? -62.562 0.668   45.541 1.00 54.08  ? 503 TRP B CH2 1 
ATOM   4393  N N   . PRO B 1 302 ? -64.498 4.310   39.686 1.00 51.68  ? 504 PRO B N   1 
ATOM   4394  C CA  . PRO B 1 302 ? -63.845 3.922   38.435 1.00 51.41  ? 504 PRO B CA  1 
ATOM   4395  C C   . PRO B 1 302 ? -62.480 4.571   38.275 1.00 51.85  ? 504 PRO B C   1 
ATOM   4396  O O   . PRO B 1 302 ? -61.583 3.968   37.691 1.00 53.42  ? 504 PRO B O   1 
ATOM   4397  C CB  . PRO B 1 302 ? -64.803 4.450   37.373 1.00 50.00  ? 504 PRO B CB  1 
ATOM   4398  C CG  . PRO B 1 302 ? -66.133 4.386   38.032 1.00 49.32  ? 504 PRO B CG  1 
ATOM   4399  C CD  . PRO B 1 302 ? -65.886 4.743   39.468 1.00 50.72  ? 504 PRO B CD  1 
ATOM   4400  N N   . GLY B 1 303 ? -62.321 5.786   38.784 1.00 51.17  ? 505 GLY B N   1 
ATOM   4401  C CA  . GLY B 1 303 ? -61.050 6.464   38.674 1.00 51.47  ? 505 GLY B CA  1 
ATOM   4402  C C   . GLY B 1 303 ? -60.285 6.587   39.966 1.00 51.11  ? 505 GLY B C   1 
ATOM   4403  O O   . GLY B 1 303 ? -59.404 7.445   40.080 1.00 52.04  ? 505 GLY B O   1 
ATOM   4404  N N   . ALA B 1 304 ? -60.600 5.754   40.952 1.00 50.95  ? 506 ALA B N   1 
ATOM   4405  C CA  . ALA B 1 304 ? -59.984 5.864   42.264 1.00 49.72  ? 506 ALA B CA  1 
ATOM   4406  C C   . ALA B 1 304 ? -58.642 5.145   42.309 1.00 49.05  ? 506 ALA B C   1 
ATOM   4407  O O   . ALA B 1 304 ? -58.432 4.124   41.650 1.00 49.90  ? 506 ALA B O   1 
ATOM   4408  C CB  . ALA B 1 304 ? -60.913 5.293   43.331 1.00 52.47  ? 506 ALA B CB  1 
ATOM   4409  N N   . SER B 1 305 ? -57.725 5.700   43.095 1.00 48.64  ? 507 SER B N   1 
ATOM   4410  C CA  . SER B 1 305 ? -56.467 5.035   43.391 1.00 47.48  ? 507 SER B CA  1 
ATOM   4411  C C   . SER B 1 305 ? -56.680 4.074   44.550 1.00 46.43  ? 507 SER B C   1 
ATOM   4412  O O   . SER B 1 305 ? -57.143 4.477   45.621 1.00 45.93  ? 507 SER B O   1 
ATOM   4413  C CB  . SER B 1 305 ? -55.392 6.061   43.737 1.00 46.37  ? 507 SER B CB  1 
ATOM   4414  O OG  . SER B 1 305 ? -55.128 6.903   42.631 1.00 48.36  ? 507 SER B OG  1 
ATOM   4415  N N   . SER B 1 306 ? -56.359 2.801   44.338 1.00 42.95  ? 508 SER B N   1 
ATOM   4416  C CA  . SER B 1 306 ? -56.719 1.771   45.298 1.00 42.01  ? 508 SER B CA  1 
ATOM   4417  C C   . SER B 1 306 ? -55.622 0.724   45.394 1.00 41.20  ? 508 SER B C   1 
ATOM   4418  O O   . SER B 1 306 ? -54.745 0.627   44.535 1.00 41.73  ? 508 SER B O   1 
ATOM   4419  C CB  . SER B 1 306 ? -58.047 1.102   44.918 1.00 45.55  ? 508 SER B CB  1 
ATOM   4420  O OG  . SER B 1 306 ? -57.943 0.440   43.671 1.00 45.64  ? 508 SER B OG  1 
ATOM   4421  N N   . TRP B 1 307 ? -55.688 -0.057  46.468 1.00 43.04  ? 509 TRP B N   1 
ATOM   4422  C CA  . TRP B 1 307 ? -54.855 -1.232  46.657 1.00 42.48  ? 509 TRP B CA  1 
ATOM   4423  C C   . TRP B 1 307 ? -55.741 -2.457  46.826 1.00 42.06  ? 509 TRP B C   1 
ATOM   4424  O O   . TRP B 1 307 ? -56.826 -2.384  47.410 1.00 40.45  ? 509 TRP B O   1 
ATOM   4425  C CB  . TRP B 1 307 ? -53.923 -1.083  47.864 1.00 40.02  ? 509 TRP B CB  1 
ATOM   4426  C CG  . TRP B 1 307 ? -54.595 -0.671  49.142 1.00 40.69  ? 509 TRP B CG  1 
ATOM   4427  C CD1 . TRP B 1 307 ? -54.761 0.600   49.601 1.00 41.15  ? 509 TRP B CD1 1 
ATOM   4428  C CD2 . TRP B 1 307 ? -55.189 -1.529  50.124 1.00 41.06  ? 509 TRP B CD2 1 
ATOM   4429  N NE1 . TRP B 1 307 ? -55.412 0.591   50.807 1.00 41.74  ? 509 TRP B NE1 1 
ATOM   4430  C CE2 . TRP B 1 307 ? -55.687 -0.705  51.150 1.00 41.66  ? 509 TRP B CE2 1 
ATOM   4431  C CE3 . TRP B 1 307 ? -55.351 -2.913  50.233 1.00 41.50  ? 509 TRP B CE3 1 
ATOM   4432  C CZ2 . TRP B 1 307 ? -56.332 -1.219  52.271 1.00 42.18  ? 509 TRP B CZ2 1 
ATOM   4433  C CZ3 . TRP B 1 307 ? -55.983 -3.419  51.351 1.00 42.26  ? 509 TRP B CZ3 1 
ATOM   4434  C CH2 . TRP B 1 307 ? -56.469 -2.575  52.352 1.00 42.83  ? 509 TRP B CH2 1 
ATOM   4435  N N   . ALA B 1 308 ? -55.270 -3.585  46.303 1.00 45.20  ? 510 ALA B N   1 
ATOM   4436  C CA  . ALA B 1 308 ? -56.034 -4.823  46.267 1.00 45.55  ? 510 ALA B CA  1 
ATOM   4437  C C   . ALA B 1 308 ? -55.520 -5.798  47.317 1.00 46.53  ? 510 ALA B C   1 
ATOM   4438  O O   . ALA B 1 308 ? -54.309 -5.984  47.465 1.00 47.76  ? 510 ALA B O   1 
ATOM   4439  C CB  . ALA B 1 308 ? -55.960 -5.471  44.883 1.00 45.67  ? 510 ALA B CB  1 
ATOM   4440  N N   . LEU B 1 309 ? -56.448 -6.423  48.039 1.00 48.94  ? 511 LEU B N   1 
ATOM   4441  C CA  . LEU B 1 309 ? -56.110 -7.405  49.063 1.00 49.52  ? 511 LEU B CA  1 
ATOM   4442  C C   . LEU B 1 309 ? -57.044 -8.598  48.938 1.00 50.69  ? 511 LEU B C   1 
ATOM   4443  O O   . LEU B 1 309 ? -58.259 -8.448  49.095 1.00 50.50  ? 511 LEU B O   1 
ATOM   4444  C CB  . LEU B 1 309 ? -56.218 -6.800  50.460 1.00 45.22  ? 511 LEU B CB  1 
ATOM   4445  C CG  . LEU B 1 309 ? -55.911 -7.752  51.611 1.00 45.28  ? 511 LEU B CG  1 
ATOM   4446  C CD1 . LEU B 1 309 ? -54.447 -8.150  51.582 1.00 45.45  ? 511 LEU B CD1 1 
ATOM   4447  C CD2 . LEU B 1 309 ? -56.294 -7.132  52.936 1.00 45.14  ? 511 LEU B CD2 1 
ATOM   4448  N N   . ASN B 1 310 ? -56.475 -9.774  48.671 1.00 50.50  ? 512 ASN B N   1 
ATOM   4449  C CA  . ASN B 1 310 ? -57.230 -11.027 48.626 1.00 52.33  ? 512 ASN B CA  1 
ATOM   4450  C C   . ASN B 1 310 ? -58.413 -10.928 47.663 1.00 52.98  ? 512 ASN B C   1 
ATOM   4451  O O   . ASN B 1 310 ? -59.510 -11.420 47.934 1.00 53.49  ? 512 ASN B O   1 
ATOM   4452  C CB  . ASN B 1 310 ? -57.693 -11.433 50.027 1.00 53.32  ? 512 ASN B CB  1 
ATOM   4453  C CG  . ASN B 1 310 ? -58.191 -12.864 50.089 1.00 55.59  ? 512 ASN B CG  1 
ATOM   4454  O OD1 . ASN B 1 310 ? -57.735 -13.725 49.338 1.00 57.54  ? 512 ASN B OD1 1 
ATOM   4455  N ND2 . ASN B 1 310 ? -59.131 -13.125 50.989 1.00 54.92  ? 512 ASN B ND2 1 
ATOM   4456  N N   . GLY B 1 311 ? -58.191 -10.276 46.527 1.00 47.87  ? 513 GLY B N   1 
ATOM   4457  C CA  . GLY B 1 311 ? -59.217 -10.112 45.523 1.00 47.85  ? 513 GLY B CA  1 
ATOM   4458  C C   . GLY B 1 311 ? -60.141 -8.934  45.738 1.00 48.69  ? 513 GLY B C   1 
ATOM   4459  O O   . GLY B 1 311 ? -60.881 -8.575  44.814 1.00 49.99  ? 513 GLY B O   1 
ATOM   4460  N N   . ARG B 1 312 ? -60.132 -8.330  46.921 1.00 50.41  ? 514 ARG B N   1 
ATOM   4461  C CA  . ARG B 1 312 ? -60.950 -7.161  47.209 1.00 50.80  ? 514 ARG B CA  1 
ATOM   4462  C C   . ARG B 1 312 ? -60.139 -5.891  46.998 1.00 50.55  ? 514 ARG B C   1 
ATOM   4463  O O   . ARG B 1 312 ? -58.994 -5.789  47.446 1.00 51.07  ? 514 ARG B O   1 
ATOM   4464  C CB  . ARG B 1 312 ? -61.488 -7.203  48.640 1.00 46.34  ? 514 ARG B CB  1 
ATOM   4465  C CG  . ARG B 1 312 ? -62.552 -8.254  48.877 1.00 50.34  ? 514 ARG B CG  1 
ATOM   4466  C CD  . ARG B 1 312 ? -62.902 -8.343  50.349 1.00 54.39  ? 514 ARG B CD  1 
ATOM   4467  N NE  . ARG B 1 312 ? -61.769 -8.815  51.135 1.00 58.58  ? 514 ARG B NE  1 
ATOM   4468  C CZ  . ARG B 1 312 ? -61.790 -8.982  52.452 1.00 61.00  ? 514 ARG B CZ  1 
ATOM   4469  N NH1 . ARG B 1 312 ? -62.890 -8.706  53.137 1.00 61.64  ? 514 ARG B NH1 1 
ATOM   4470  N NH2 . ARG B 1 312 ? -60.711 -9.420  53.084 1.00 62.01  ? 514 ARG B NH2 1 
ATOM   4471  N N   . ASN B 1 313 ? -60.741 -4.924  46.316 1.00 51.61  ? 515 ASN B N   1 
ATOM   4472  C CA  . ASN B 1 313 ? -60.102 -3.648  46.034 1.00 50.82  ? 515 ASN B CA  1 
ATOM   4473  C C   . ASN B 1 313 ? -60.534 -2.625  47.072 1.00 49.41  ? 515 ASN B C   1 
ATOM   4474  O O   . ASN B 1 313 ? -61.714 -2.267  47.143 1.00 49.61  ? 515 ASN B O   1 
ATOM   4475  C CB  . ASN B 1 313 ? -60.456 -3.156  44.632 1.00 50.08  ? 515 ASN B CB  1 
ATOM   4476  C CG  . ASN B 1 313 ? -59.839 -4.006  43.549 1.00 51.69  ? 515 ASN B CG  1 
ATOM   4477  O OD1 . ASN B 1 313 ? -58.649 -3.901  43.269 1.00 52.55  ? 515 ASN B OD1 1 
ATOM   4478  N ND2 . ASN B 1 313 ? -60.647 -4.856  42.932 1.00 53.55  ? 515 ASN B ND2 1 
ATOM   4479  N N   . SER B 1 314 ? -59.573 -2.116  47.835 1.00 50.22  ? 516 SER B N   1 
ATOM   4480  C CA  . SER B 1 314 ? -59.841 -1.096  48.840 1.00 49.25  ? 516 SER B CA  1 
ATOM   4481  C C   . SER B 1 314 ? -59.301 0.236   48.348 1.00 48.91  ? 516 SER B C   1 
ATOM   4482  O O   . SER B 1 314 ? -58.216 0.300   47.784 1.00 48.57  ? 516 SER B O   1 
ATOM   4483  C CB  . SER B 1 314 ? -59.181 -1.444  50.172 1.00 48.06  ? 516 SER B CB  1 
ATOM   4484  O OG  . SER B 1 314 ? -59.761 -2.593  50.756 1.00 49.44  ? 516 SER B OG  1 
ATOM   4485  N N   . LEU B 1 315 ? -60.068 1.297   48.548 1.00 47.35  ? 517 LEU B N   1 
ATOM   4486  C CA  . LEU B 1 315 ? -59.657 2.628   48.136 1.00 47.66  ? 517 LEU B CA  1 
ATOM   4487  C C   . LEU B 1 315 ? -58.468 3.068   48.966 1.00 48.09  ? 517 LEU B C   1 
ATOM   4488  O O   . LEU B 1 315 ? -58.397 2.765   50.150 1.00 48.94  ? 517 LEU B O   1 
ATOM   4489  C CB  . LEU B 1 315 ? -60.807 3.603   48.345 1.00 50.59  ? 517 LEU B CB  1 
ATOM   4490  C CG  . LEU B 1 315 ? -60.707 4.962   47.668 1.00 51.36  ? 517 LEU B CG  1 
ATOM   4491  C CD1 . LEU B 1 315 ? -60.758 4.792   46.160 1.00 51.17  ? 517 LEU B CD1 1 
ATOM   4492  C CD2 . LEU B 1 315 ? -61.843 5.848   48.145 1.00 53.21  ? 517 LEU B CD2 1 
ATOM   4493  N N   . MET B 1 316 ? -57.533 3.783   48.353 1.00 48.65  ? 518 MET B N   1 
ATOM   4494  C CA  . MET B 1 316 ? -56.359 4.262   49.072 1.00 48.56  ? 518 MET B CA  1 
ATOM   4495  C C   . MET B 1 316 ? -56.722 5.571   49.750 1.00 48.36  ? 518 MET B C   1 
ATOM   4496  O O   . MET B 1 316 ? -56.403 6.647   49.257 1.00 48.18  ? 518 MET B O   1 
ATOM   4497  C CB  . MET B 1 316 ? -55.188 4.464   48.113 1.00 45.26  ? 518 MET B CB  1 
ATOM   4498  C CG  . MET B 1 316 ? -53.921 4.982   48.767 1.00 46.62  ? 518 MET B CG  1 
ATOM   4499  S SD  . MET B 1 316 ? -52.888 3.691   49.479 1.00 49.31  ? 518 MET B SD  1 
ATOM   4500  C CE  . MET B 1 316 ? -52.376 2.805   48.013 1.00 47.07  ? 518 MET B CE  1 
ATOM   4501  N N   . ASN B 1 317 ? -57.402 5.465   50.884 1.00 51.75  ? 519 ASN B N   1 
ATOM   4502  C CA  . ASN B 1 317 ? -57.843 6.629   51.633 1.00 51.16  ? 519 ASN B CA  1 
ATOM   4503  C C   . ASN B 1 317 ? -57.216 6.635   53.012 1.00 50.94  ? 519 ASN B C   1 
ATOM   4504  O O   . ASN B 1 317 ? -57.345 5.663   53.745 1.00 51.72  ? 519 ASN B O   1 
ATOM   4505  C CB  . ASN B 1 317 ? -59.365 6.578   51.770 1.00 52.24  ? 519 ASN B CB  1 
ATOM   4506  C CG  . ASN B 1 317 ? -59.936 7.810   52.438 1.00 52.68  ? 519 ASN B CG  1 
ATOM   4507  O OD1 . ASN B 1 317 ? -59.405 8.911   52.295 1.00 55.03  ? 519 ASN B OD1 1 
ATOM   4508  N ND2 . ASN B 1 317 ? -61.032 7.633   53.163 1.00 51.42  ? 519 ASN B ND2 1 
ATOM   4509  N N   . PRO B 1 318 ? -56.577 7.749   53.402 1.00 49.63  ? 520 PRO B N   1 
ATOM   4510  C CA  . PRO B 1 318 ? -55.887 8.789   52.630 1.00 49.44  ? 520 PRO B CA  1 
ATOM   4511  C C   . PRO B 1 318 ? -54.653 8.311   51.860 1.00 49.98  ? 520 PRO B C   1 
ATOM   4512  O O   . PRO B 1 318 ? -54.414 8.784   50.755 1.00 49.74  ? 520 PRO B O   1 
ATOM   4513  C CB  . PRO B 1 318 ? -55.485 9.809   53.694 1.00 47.27  ? 520 PRO B CB  1 
ATOM   4514  C CG  . PRO B 1 318 ? -55.417 9.031   54.951 1.00 47.28  ? 520 PRO B CG  1 
ATOM   4515  C CD  . PRO B 1 318 ? -56.525 8.033   54.845 1.00 48.10  ? 520 PRO B CD  1 
ATOM   4516  N N   . GLY B 1 319 ? -53.874 7.403   52.432 1.00 44.75  ? 521 GLY B N   1 
ATOM   4517  C CA  . GLY B 1 319 ? -52.676 6.942   51.759 1.00 45.77  ? 521 GLY B CA  1 
ATOM   4518  C C   . GLY B 1 319 ? -51.463 7.749   52.170 1.00 46.59  ? 521 GLY B C   1 
ATOM   4519  O O   . GLY B 1 319 ? -51.499 8.444   53.180 1.00 47.08  ? 521 GLY B O   1 
ATOM   4520  N N   . PRO B 1 320 ? -50.383 7.676   51.381 1.00 43.79  ? 522 PRO B N   1 
ATOM   4521  C CA  . PRO B 1 320 ? -49.135 8.375   51.706 1.00 43.52  ? 522 PRO B CA  1 
ATOM   4522  C C   . PRO B 1 320 ? -49.309 9.884   51.786 1.00 43.23  ? 522 PRO B C   1 
ATOM   4523  O O   . PRO B 1 320 ? -50.071 10.464  51.020 1.00 44.31  ? 522 PRO B O   1 
ATOM   4524  C CB  . PRO B 1 320 ? -48.219 8.027   50.527 1.00 40.30  ? 522 PRO B CB  1 
ATOM   4525  C CG  . PRO B 1 320 ? -48.826 6.821   49.898 1.00 41.62  ? 522 PRO B CG  1 
ATOM   4526  C CD  . PRO B 1 320 ? -50.300 6.965   50.098 1.00 41.04  ? 522 PRO B CD  1 
ATOM   4527  N N   . ALA B 1 321 ? -48.614 10.507  52.731 1.00 43.41  ? 523 ALA B N   1 
ATOM   4528  C CA  . ALA B 1 321 ? -48.688 11.948  52.918 1.00 43.21  ? 523 ALA B CA  1 
ATOM   4529  C C   . ALA B 1 321 ? -48.005 12.693  51.782 1.00 43.32  ? 523 ALA B C   1 
ATOM   4530  O O   . ALA B 1 321 ? -46.808 12.566  51.573 1.00 43.01  ? 523 ALA B O   1 
ATOM   4531  C CB  . ALA B 1 321 ? -48.078 12.341  54.252 1.00 39.50  ? 523 ALA B CB  1 
ATOM   4532  N N   . MET B 1 322 ? -48.784 13.479  51.057 1.00 41.69  ? 524 MET B N   1 
ATOM   4533  C CA  . MET B 1 322 ? -48.285 14.261  49.938 1.00 42.52  ? 524 MET B CA  1 
ATOM   4534  C C   . MET B 1 322 ? -48.947 15.628  49.965 1.00 42.94  ? 524 MET B C   1 
ATOM   4535  O O   . MET B 1 322 ? -49.922 15.844  50.687 1.00 44.53  ? 524 MET B O   1 
ATOM   4536  C CB  . MET B 1 322 ? -48.572 13.572  48.603 1.00 39.08  ? 524 MET B CB  1 
ATOM   4537  C CG  . MET B 1 322 ? -47.864 12.253  48.414 1.00 41.78  ? 524 MET B CG  1 
ATOM   4538  S SD  . MET B 1 322 ? -48.289 11.527  46.830 1.00 45.37  ? 524 MET B SD  1 
ATOM   4539  C CE  . MET B 1 322 ? -49.972 11.029  47.168 1.00 47.45  ? 524 MET B CE  1 
ATOM   4540  N N   . ALA B 1 323 ? -48.408 16.549  49.174 1.00 42.33  ? 525 ALA B N   1 
ATOM   4541  C CA  . ALA B 1 323 ? -49.012 17.869  49.067 1.00 43.33  ? 525 ALA B CA  1 
ATOM   4542  C C   . ALA B 1 323 ? -50.371 17.769  48.387 1.00 44.70  ? 525 ALA B C   1 
ATOM   4543  O O   . ALA B 1 323 ? -50.506 17.149  47.329 1.00 45.16  ? 525 ALA B O   1 
ATOM   4544  C CB  . ALA B 1 323 ? -48.095 18.811  48.291 1.00 41.86  ? 525 ALA B CB  1 
ATOM   4545  N N   . SER B 1 324 ? -51.382 18.385  49.002 1.00 47.55  ? 526 SER B N   1 
ATOM   4546  C CA  . SER B 1 324 ? -52.731 18.324  48.449 1.00 49.34  ? 526 SER B CA  1 
ATOM   4547  C C   . SER B 1 324 ? -52.821 19.067  47.123 1.00 50.51  ? 526 SER B C   1 
ATOM   4548  O O   . SER B 1 324 ? -53.561 18.655  46.224 1.00 50.66  ? 526 SER B O   1 
ATOM   4549  C CB  . SER B 1 324 ? -53.733 18.895  49.450 1.00 50.00  ? 526 SER B CB  1 
ATOM   4550  O OG  . SER B 1 324 ? -53.771 18.117  50.633 1.00 52.73  ? 526 SER B OG  1 
ATOM   4551  N N   . HIS B 1 325 ? -52.065 20.144  46.983 1.00 51.03  ? 527 HIS B N   1 
ATOM   4552  C CA  . HIS B 1 325 ? -52.082 20.898  45.745 1.00 53.51  ? 527 HIS B CA  1 
ATOM   4553  C C   . HIS B 1 325 ? -50.817 21.713  45.619 1.00 55.05  ? 527 HIS B C   1 
ATOM   4554  O O   . HIS B 1 325 ? -50.134 21.962  46.604 1.00 55.07  ? 527 HIS B O   1 
ATOM   4555  C CB  . HIS B 1 325 ? -53.299 21.819  45.691 1.00 57.12  ? 527 HIS B CB  1 
ATOM   4556  C CG  . HIS B 1 325 ? -53.309 22.869  46.756 1.00 57.94  ? 527 HIS B CG  1 
ATOM   4557  N ND1 . HIS B 1 325 ? -52.571 24.027  46.665 1.00 58.50  ? 527 HIS B ND1 1 
ATOM   4558  C CD2 . HIS B 1 325 ? -53.975 22.939  47.931 1.00 57.97  ? 527 HIS B CD2 1 
ATOM   4559  C CE1 . HIS B 1 325 ? -52.774 24.762  47.743 1.00 57.56  ? 527 HIS B CE1 1 
ATOM   4560  N NE2 . HIS B 1 325 ? -53.625 24.125  48.525 1.00 57.50  ? 527 HIS B NE2 1 
ATOM   4561  N N   . LYS B 1 326 ? -50.507 22.123  44.396 1.00 53.87  ? 528 LYS B N   1 
ATOM   4562  C CA  . LYS B 1 326 ? -49.336 22.944  44.123 1.00 56.63  ? 528 LYS B CA  1 
ATOM   4563  C C   . LYS B 1 326 ? -49.568 24.376  44.574 1.00 58.63  ? 528 LYS B C   1 
ATOM   4564  O O   . LYS B 1 326 ? -50.706 24.805  44.759 1.00 58.15  ? 528 LYS B O   1 
ATOM   4565  C CB  . LYS B 1 326 ? -48.983 22.918  42.639 1.00 52.33  ? 528 LYS B CB  1 
ATOM   4566  C CG  . LYS B 1 326 ? -48.453 21.583  42.155 1.00 52.93  ? 528 LYS B CG  1 
ATOM   4567  C CD  . LYS B 1 326 ? -47.731 21.728  40.831 1.00 55.11  ? 528 LYS B CD  1 
ATOM   4568  C CE  . LYS B 1 326 ? -48.611 22.392  39.793 1.00 55.51  ? 528 LYS B CE  1 
ATOM   4569  N NZ  . LYS B 1 326 ? -47.827 22.771  38.588 1.00 55.91  ? 528 LYS B NZ  1 
ATOM   4570  N N   . GLU B 1 327 ? -48.487 25.125  44.753 1.00 53.81  ? 529 GLU B N   1 
ATOM   4571  C CA  . GLU B 1 327 ? -48.613 26.507  45.170 1.00 57.53  ? 529 GLU B CA  1 
ATOM   4572  C C   . GLU B 1 327 ? -49.399 27.237  44.096 1.00 58.24  ? 529 GLU B C   1 
ATOM   4573  O O   . GLU B 1 327 ? -49.120 27.091  42.907 1.00 58.28  ? 529 GLU B O   1 
ATOM   4574  C CB  . GLU B 1 327 ? -47.229 27.138  45.289 1.00 55.09  ? 529 GLU B CB  1 
ATOM   4575  C CG  . GLU B 1 327 ? -47.197 28.464  46.027 1.00 60.87  ? 529 GLU B CG  1 
ATOM   4576  C CD  . GLU B 1 327 ? -46.881 28.298  47.499 1.00 63.88  ? 529 GLU B CD  1 
ATOM   4577  O OE1 . GLU B 1 327 ? -45.877 27.630  47.820 1.00 64.27  ? 529 GLU B OE1 1 
ATOM   4578  O OE2 . GLU B 1 327 ? -47.630 28.838  48.337 1.00 65.83  ? 529 GLU B OE2 1 
ATOM   4579  N N   . GLY B 1 328 ? -50.363 28.048  44.516 1.00 61.75  ? 530 GLY B N   1 
ATOM   4580  C CA  . GLY B 1 328 ? -51.179 28.798  43.581 1.00 62.48  ? 530 GLY B CA  1 
ATOM   4581  C C   . GLY B 1 328 ? -52.368 28.078  42.971 1.00 62.97  ? 530 GLY B C   1 
ATOM   4582  O O   . GLY B 1 328 ? -52.995 28.598  42.052 1.00 63.93  ? 530 GLY B O   1 
ATOM   4583  N N   . GLU B 1 329 ? -52.681 26.885  43.463 1.00 64.16  ? 531 GLU B N   1 
ATOM   4584  C CA  . GLU B 1 329 ? -53.827 26.137  42.950 1.00 63.68  ? 531 GLU B CA  1 
ATOM   4585  C C   . GLU B 1 329 ? -54.679 25.684  44.124 1.00 61.98  ? 531 GLU B C   1 
ATOM   4586  O O   . GLU B 1 329 ? -54.784 24.498  44.405 1.00 61.96  ? 531 GLU B O   1 
ATOM   4587  C CB  . GLU B 1 329 ? -53.364 24.912  42.168 1.00 55.20  ? 531 GLU B CB  1 
ATOM   4588  C CG  . GLU B 1 329 ? -52.448 25.215  40.998 1.00 59.25  ? 531 GLU B CG  1 
ATOM   4589  C CD  . GLU B 1 329 ? -51.934 23.954  40.336 1.00 62.79  ? 531 GLU B CD  1 
ATOM   4590  O OE1 . GLU B 1 329 ? -51.777 22.935  41.040 1.00 64.96  ? 531 GLU B OE1 1 
ATOM   4591  O OE2 . GLU B 1 329 ? -51.686 23.981  39.113 1.00 63.78  ? 531 GLU B OE2 1 
ATOM   4592  N N   . ASP B 1 330 ? -55.326 26.639  44.773 1.00 67.15  ? 532 ASP B N   1 
ATOM   4593  C CA  . ASP B 1 330 ? -56.146 26.362  45.946 1.00 65.50  ? 532 ASP B CA  1 
ATOM   4594  C C   . ASP B 1 330 ? -57.352 25.453  45.703 1.00 62.31  ? 532 ASP B C   1 
ATOM   4595  O O   . ASP B 1 330 ? -57.681 24.619  46.545 1.00 61.29  ? 532 ASP B O   1 
ATOM   4596  C CB  . ASP B 1 330 ? -56.591 27.676  46.591 1.00 63.47  ? 532 ASP B CB  1 
ATOM   4597  C CG  . ASP B 1 330 ? -56.790 28.781  45.574 1.00 68.57  ? 532 ASP B CG  1 
ATOM   4598  O OD1 . ASP B 1 330 ? -56.808 28.480  44.363 1.00 71.07  ? 532 ASP B OD1 1 
ATOM   4599  O OD2 . ASP B 1 330 ? -56.922 29.953  45.982 1.00 71.71  ? 532 ASP B OD2 1 
ATOM   4600  N N   . ARG B 1 331 ? -58.018 25.623  44.567 1.00 62.11  ? 533 ARG B N   1 
ATOM   4601  C CA  . ARG B 1 331 ? -59.203 24.827  44.268 1.00 58.49  ? 533 ARG B CA  1 
ATOM   4602  C C   . ARG B 1 331 ? -59.017 23.311  44.132 1.00 57.14  ? 533 ARG B C   1 
ATOM   4603  O O   . ARG B 1 331 ? -59.851 22.554  44.617 1.00 56.36  ? 533 ARG B O   1 
ATOM   4604  C CB  . ARG B 1 331 ? -59.935 25.383  43.047 1.00 55.77  ? 533 ARG B CB  1 
ATOM   4605  C CG  . ARG B 1 331 ? -59.163 25.321  41.747 1.00 53.60  ? 533 ARG B CG  1 
ATOM   4606  C CD  . ARG B 1 331 ? -60.059 25.751  40.601 1.00 53.75  ? 533 ARG B CD  1 
ATOM   4607  N NE  . ARG B 1 331 ? -59.402 25.609  39.311 1.00 54.26  ? 533 ARG B NE  1 
ATOM   4608  C CZ  . ARG B 1 331 ? -58.809 26.603  38.665 1.00 54.38  ? 533 ARG B CZ  1 
ATOM   4609  N NH1 . ARG B 1 331 ? -58.798 27.818  39.188 1.00 54.88  ? 533 ARG B NH1 1 
ATOM   4610  N NH2 . ARG B 1 331 ? -58.231 26.379  37.495 1.00 52.67  ? 533 ARG B NH2 1 
ATOM   4611  N N   . PHE B 1 332 ? -57.939 22.865  43.490 1.00 56.13  ? 534 PHE B N   1 
ATOM   4612  C CA  . PHE B 1 332 ? -57.710 21.429  43.291 1.00 53.65  ? 534 PHE B CA  1 
ATOM   4613  C C   . PHE B 1 332 ? -57.328 20.658  44.554 1.00 52.67  ? 534 PHE B C   1 
ATOM   4614  O O   . PHE B 1 332 ? -56.628 21.179  45.416 1.00 53.67  ? 534 PHE B O   1 
ATOM   4615  C CB  . PHE B 1 332 ? -56.638 21.203  42.230 1.00 52.10  ? 534 PHE B CB  1 
ATOM   4616  C CG  . PHE B 1 332 ? -56.905 21.902  40.932 1.00 52.32  ? 534 PHE B CG  1 
ATOM   4617  C CD1 . PHE B 1 332 ? -57.916 21.474  40.097 1.00 52.78  ? 534 PHE B CD1 1 
ATOM   4618  C CD2 . PHE B 1 332 ? -56.125 22.972  40.540 1.00 52.95  ? 534 PHE B CD2 1 
ATOM   4619  C CE1 . PHE B 1 332 ? -58.156 22.109  38.898 1.00 52.96  ? 534 PHE B CE1 1 
ATOM   4620  C CE2 . PHE B 1 332 ? -56.358 23.612  39.343 1.00 52.78  ? 534 PHE B CE2 1 
ATOM   4621  C CZ  . PHE B 1 332 ? -57.375 23.181  38.520 1.00 52.69  ? 534 PHE B CZ  1 
ATOM   4622  N N   . PHE B 1 333 ? -57.783 19.408  44.646 1.00 53.80  ? 535 PHE B N   1 
ATOM   4623  C CA  . PHE B 1 333 ? -57.484 18.554  45.785 1.00 51.92  ? 535 PHE B CA  1 
ATOM   4624  C C   . PHE B 1 333 ? -57.498 17.099  45.341 1.00 50.94  ? 535 PHE B C   1 
ATOM   4625  O O   . PHE B 1 333 ? -58.204 16.745  44.390 1.00 50.45  ? 535 PHE B O   1 
ATOM   4626  C CB  . PHE B 1 333 ? -58.489 18.769  46.932 1.00 51.31  ? 535 PHE B CB  1 
ATOM   4627  C CG  . PHE B 1 333 ? -59.917 18.465  46.569 1.00 51.56  ? 535 PHE B CG  1 
ATOM   4628  C CD1 . PHE B 1 333 ? -60.448 17.205  46.778 1.00 50.60  ? 535 PHE B CD1 1 
ATOM   4629  C CD2 . PHE B 1 333 ? -60.730 19.444  46.027 1.00 51.81  ? 535 PHE B CD2 1 
ATOM   4630  C CE1 . PHE B 1 333 ? -61.759 16.925  46.448 1.00 49.47  ? 535 PHE B CE1 1 
ATOM   4631  C CE2 . PHE B 1 333 ? -62.041 19.168  45.694 1.00 50.74  ? 535 PHE B CE2 1 
ATOM   4632  C CZ  . PHE B 1 333 ? -62.555 17.907  45.907 1.00 49.63  ? 535 PHE B CZ  1 
ATOM   4633  N N   . PRO B 1 334 ? -56.724 16.238  46.000 1.00 50.01  ? 536 PRO B N   1 
ATOM   4634  C CA  . PRO B 1 334 ? -56.746 14.819  45.643 1.00 49.61  ? 536 PRO B CA  1 
ATOM   4635  C C   . PRO B 1 334 ? -58.086 14.192  45.987 1.00 49.38  ? 536 PRO B C   1 
ATOM   4636  O O   . PRO B 1 334 ? -58.726 14.545  46.980 1.00 49.17  ? 536 PRO B O   1 
ATOM   4637  C CB  . PRO B 1 334 ? -55.616 14.224  46.488 1.00 47.75  ? 536 PRO B CB  1 
ATOM   4638  C CG  . PRO B 1 334 ? -55.528 15.124  47.659 1.00 47.82  ? 536 PRO B CG  1 
ATOM   4639  C CD  . PRO B 1 334 ? -55.814 16.501  47.127 1.00 47.74  ? 536 PRO B CD  1 
ATOM   4640  N N   . LEU B 1 335 ? -58.507 13.254  45.140 1.00 51.84  ? 537 LEU B N   1 
ATOM   4641  C CA  . LEU B 1 335 ? -59.817 12.627  45.266 1.00 52.24  ? 537 LEU B CA  1 
ATOM   4642  C C   . LEU B 1 335 ? -59.986 12.007  46.647 1.00 53.20  ? 537 LEU B C   1 
ATOM   4643  O O   . LEU B 1 335 ? -60.792 12.481  47.453 1.00 53.49  ? 537 LEU B O   1 
ATOM   4644  C CB  . LEU B 1 335 ? -60.005 11.572  44.174 1.00 52.39  ? 537 LEU B CB  1 
ATOM   4645  C CG  . LEU B 1 335 ? -61.399 10.976  43.966 1.00 52.29  ? 537 LEU B CG  1 
ATOM   4646  C CD1 . LEU B 1 335 ? -61.596 10.616  42.508 1.00 52.35  ? 537 LEU B CD1 1 
ATOM   4647  C CD2 . LEU B 1 335 ? -61.630 9.758   44.839 1.00 53.20  ? 537 LEU B CD2 1 
ATOM   4648  N N   . SER B 1 336 ? -59.234 10.945  46.921 1.00 49.19  ? 538 SER B N   1 
ATOM   4649  C CA  . SER B 1 336 ? -59.264 10.267  48.207 1.00 50.61  ? 538 SER B CA  1 
ATOM   4650  C C   . SER B 1 336 ? -58.135 10.697  49.135 1.00 50.84  ? 538 SER B C   1 
ATOM   4651  O O   . SER B 1 336 ? -58.008 10.147  50.231 1.00 51.22  ? 538 SER B O   1 
ATOM   4652  C CB  . SER B 1 336 ? -59.219 8.754   47.999 1.00 50.17  ? 538 SER B CB  1 
ATOM   4653  O OG  . SER B 1 336 ? -58.015 8.365   47.363 1.00 53.10  ? 538 SER B OG  1 
ATOM   4654  N N   . GLY B 1 337 ? -57.314 11.659  48.726 1.00 49.23  ? 539 GLY B N   1 
ATOM   4655  C CA  . GLY B 1 337 ? -56.088 11.952  49.446 1.00 50.37  ? 539 GLY B CA  1 
ATOM   4656  C C   . GLY B 1 337 ? -56.233 12.721  50.741 1.00 50.96  ? 539 GLY B C   1 
ATOM   4657  O O   . GLY B 1 337 ? -55.273 12.772  51.515 1.00 53.32  ? 539 GLY B O   1 
ATOM   4658  N N   . SER B 1 338 ? -57.388 13.320  51.003 1.00 53.47  ? 540 SER B N   1 
ATOM   4659  C CA  . SER B 1 338 ? -57.555 14.183  52.161 1.00 53.50  ? 540 SER B CA  1 
ATOM   4660  C C   . SER B 1 338 ? -58.608 13.621  53.105 1.00 52.27  ? 540 SER B C   1 
ATOM   4661  O O   . SER B 1 338 ? -59.522 12.899  52.700 1.00 52.25  ? 540 SER B O   1 
ATOM   4662  C CB  . SER B 1 338 ? -57.948 15.606  51.744 1.00 53.38  ? 540 SER B CB  1 
ATOM   4663  O OG  . SER B 1 338 ? -56.910 16.227  51.009 1.00 54.93  ? 540 SER B OG  1 
ATOM   4664  N N   . LEU B 1 339 ? -58.461 13.966  54.381 1.00 54.12  ? 541 LEU B N   1 
ATOM   4665  C CA  . LEU B 1 339 ? -59.484 13.674  55.372 1.00 52.93  ? 541 LEU B CA  1 
ATOM   4666  C C   . LEU B 1 339 ? -60.636 14.654  55.201 1.00 52.71  ? 541 LEU B C   1 
ATOM   4667  O O   . LEU B 1 339 ? -60.416 15.838  54.932 1.00 53.20  ? 541 LEU B O   1 
ATOM   4668  C CB  . LEU B 1 339 ? -58.910 13.778  56.783 1.00 53.21  ? 541 LEU B CB  1 
ATOM   4669  C CG  . LEU B 1 339 ? -57.776 12.822  57.145 1.00 52.29  ? 541 LEU B CG  1 
ATOM   4670  C CD1 . LEU B 1 339 ? -57.264 13.124  58.539 1.00 51.82  ? 541 LEU B CD1 1 
ATOM   4671  C CD2 . LEU B 1 339 ? -58.235 11.382  57.039 1.00 51.67  ? 541 LEU B CD2 1 
ATOM   4672  N N   . ILE B 1 340 ? -61.863 14.165  55.348 1.00 50.44  ? 542 ILE B N   1 
ATOM   4673  C CA  . ILE B 1 340 ? -63.054 14.988  55.184 1.00 50.83  ? 542 ILE B CA  1 
ATOM   4674  C C   . ILE B 1 340 ? -63.921 14.819  56.420 1.00 50.29  ? 542 ILE B C   1 
ATOM   4675  O O   . ILE B 1 340 ? -64.433 13.724  56.680 1.00 49.29  ? 542 ILE B O   1 
ATOM   4676  C CB  . ILE B 1 340 ? -63.834 14.621  53.914 1.00 47.62  ? 542 ILE B CB  1 
ATOM   4677  C CG1 . ILE B 1 340 ? -62.971 14.855  52.676 1.00 50.46  ? 542 ILE B CG1 1 
ATOM   4678  C CG2 . ILE B 1 340 ? -65.095 15.452  53.816 1.00 48.90  ? 542 ILE B CG2 1 
ATOM   4679  C CD1 . ILE B 1 340 ? -63.575 14.317  51.405 1.00 52.30  ? 542 ILE B CD1 1 
ATOM   4680  N N   . PHE B 1 341 ? -64.092 15.898  57.173 1.00 48.16  ? 543 PHE B N   1 
ATOM   4681  C CA  . PHE B 1 341 ? -64.909 15.864  58.377 1.00 48.03  ? 543 PHE B CA  1 
ATOM   4682  C C   . PHE B 1 341 ? -66.338 16.298  58.075 1.00 47.44  ? 543 PHE B C   1 
ATOM   4683  O O   . PHE B 1 341 ? -67.094 16.653  58.977 1.00 46.27  ? 543 PHE B O   1 
ATOM   4684  C CB  . PHE B 1 341 ? -64.307 16.758  59.460 1.00 50.69  ? 543 PHE B CB  1 
ATOM   4685  C CG  . PHE B 1 341 ? -62.948 16.317  59.924 1.00 51.18  ? 543 PHE B CG  1 
ATOM   4686  C CD1 . PHE B 1 341 ? -62.817 15.311  60.862 1.00 51.26  ? 543 PHE B CD1 1 
ATOM   4687  C CD2 . PHE B 1 341 ? -61.804 16.915  59.426 1.00 51.03  ? 543 PHE B CD2 1 
ATOM   4688  C CE1 . PHE B 1 341 ? -61.571 14.903  61.292 1.00 50.81  ? 543 PHE B CE1 1 
ATOM   4689  C CE2 . PHE B 1 341 ? -60.555 16.514  59.855 1.00 50.71  ? 543 PHE B CE2 1 
ATOM   4690  C CZ  . PHE B 1 341 ? -60.438 15.505  60.789 1.00 50.57  ? 543 PHE B CZ  1 
ATOM   4691  N N   . VAL B 1 356 ? -69.224 19.768  54.634 1.00 51.46  ? 558 VAL B N   1 
ATOM   4692  C CA  . VAL B 1 356 ? -68.012 18.976  54.796 1.00 50.65  ? 558 VAL B CA  1 
ATOM   4693  C C   . VAL B 1 356 ? -66.784 19.881  54.807 1.00 50.50  ? 558 VAL B C   1 
ATOM   4694  O O   . VAL B 1 356 ? -66.783 20.947  54.195 1.00 50.50  ? 558 VAL B O   1 
ATOM   4695  C CB  . VAL B 1 356 ? -67.895 17.915  53.693 1.00 50.61  ? 558 VAL B CB  1 
ATOM   4696  C CG1 . VAL B 1 356 ? -69.070 16.953  53.764 1.00 54.16  ? 558 VAL B CG1 1 
ATOM   4697  C CG2 . VAL B 1 356 ? -67.813 18.573  52.327 1.00 50.63  ? 558 VAL B CG2 1 
ATOM   4698  N N   . MET B 1 357 ? -65.739 19.453  55.510 1.00 52.32  ? 559 MET B N   1 
ATOM   4699  C CA  . MET B 1 357 ? -64.500 20.215  55.632 1.00 52.59  ? 559 MET B CA  1 
ATOM   4700  C C   . MET B 1 357 ? -63.357 19.382  55.066 1.00 52.43  ? 559 MET B C   1 
ATOM   4701  O O   . MET B 1 357 ? -62.984 18.357  55.645 1.00 51.88  ? 559 MET B O   1 
ATOM   4702  C CB  . MET B 1 357 ? -64.235 20.592  57.087 1.00 52.85  ? 559 MET B CB  1 
ATOM   4703  C CG  . MET B 1 357 ? -65.257 21.552  57.661 1.00 57.08  ? 559 MET B CG  1 
ATOM   4704  S SD  . MET B 1 357 ? -64.884 22.062  59.347 1.00 61.53  ? 559 MET B SD  1 
ATOM   4705  C CE  . MET B 1 357 ? -65.318 20.580  60.250 1.00 61.23  ? 559 MET B CE  1 
ATOM   4706  N N   . ILE B 1 358 ? -62.797 19.810  53.941 1.00 52.95  ? 560 ILE B N   1 
ATOM   4707  C CA  . ILE B 1 358 ? -61.702 19.085  53.310 1.00 52.90  ? 560 ILE B CA  1 
ATOM   4708  C C   . ILE B 1 358 ? -60.346 19.690  53.654 1.00 54.95  ? 560 ILE B C   1 
ATOM   4709  O O   . ILE B 1 358 ? -60.003 20.762  53.165 1.00 54.94  ? 560 ILE B O   1 
ATOM   4710  C CB  . ILE B 1 358 ? -61.847 19.087  51.782 1.00 50.69  ? 560 ILE B CB  1 
ATOM   4711  C CG1 . ILE B 1 358 ? -63.298 18.840  51.379 1.00 49.22  ? 560 ILE B CG1 1 
ATOM   4712  C CG2 . ILE B 1 358 ? -60.935 18.045  51.161 1.00 49.68  ? 560 ILE B CG2 1 
ATOM   4713  C CD1 . ILE B 1 358 ? -63.487 18.687  49.887 1.00 47.38  ? 560 ILE B CD1 1 
ATOM   4714  N N   . THR B 1 359 ? -59.586 19.011  54.506 1.00 51.71  ? 561 THR B N   1 
ATOM   4715  C CA  . THR B 1 359 ? -58.265 19.490  54.904 1.00 54.76  ? 561 THR B CA  1 
ATOM   4716  C C   . THR B 1 359 ? -57.248 19.366  53.776 1.00 58.11  ? 561 THR B C   1 
ATOM   4717  O O   . THR B 1 359 ? -57.315 18.434  52.981 1.00 57.58  ? 561 THR B O   1 
ATOM   4718  C CB  . THR B 1 359 ? -57.735 18.726  56.131 1.00 54.18  ? 561 THR B CB  1 
ATOM   4719  O OG1 . THR B 1 359 ? -57.378 17.391  55.755 1.00 55.70  ? 561 THR B OG1 1 
ATOM   4720  C CG2 . THR B 1 359 ? -58.784 18.677  57.223 1.00 53.62  ? 561 THR B CG2 1 
ATOM   4721  N N   . ASN B 1 360 ? -56.314 20.309  53.697 1.00 53.62  ? 562 ASN B N   1 
ATOM   4722  C CA  . ASN B 1 360 ? -55.275 20.251  52.671 1.00 57.81  ? 562 ASN B CA  1 
ATOM   4723  C C   . ASN B 1 360 ? -53.874 20.291  53.280 1.00 59.43  ? 562 ASN B C   1 
ATOM   4724  O O   . ASN B 1 360 ? -53.582 21.143  54.113 1.00 60.69  ? 562 ASN B O   1 
ATOM   4725  C CB  . ASN B 1 360 ? -55.446 21.374  51.649 1.00 54.20  ? 562 ASN B CB  1 
ATOM   4726  C CG  . ASN B 1 360 ? -55.408 22.745  52.281 1.00 58.38  ? 562 ASN B CG  1 
ATOM   4727  O OD1 . ASN B 1 360 ? -56.150 23.027  53.219 1.00 62.70  ? 562 ASN B OD1 1 
ATOM   4728  N ND2 . ASN B 1 360 ? -54.547 23.610  51.763 1.00 60.50  ? 562 ASN B ND2 1 
ATOM   4729  N N   . GLU B 1 361 ? -53.015 19.363  52.870 1.00 54.00  ? 563 GLU B N   1 
ATOM   4730  C CA  . GLU B 1 361 ? -51.646 19.313  53.381 1.00 56.01  ? 563 GLU B CA  1 
ATOM   4731  C C   . GLU B 1 361 ? -50.691 20.208  52.590 1.00 54.91  ? 563 GLU B C   1 
ATOM   4732  O O   . GLU B 1 361 ? -49.783 19.719  51.926 1.00 56.55  ? 563 GLU B O   1 
ATOM   4733  C CB  . GLU B 1 361 ? -51.128 17.873  53.361 1.00 50.18  ? 563 GLU B CB  1 
ATOM   4734  C CG  . GLU B 1 361 ? -51.919 16.918  54.235 1.00 55.94  ? 563 GLU B CG  1 
ATOM   4735  C CD  . GLU B 1 361 ? -51.869 17.302  55.699 1.00 59.00  ? 563 GLU B CD  1 
ATOM   4736  O OE1 . GLU B 1 361 ? -50.923 18.016  56.092 1.00 59.17  ? 563 GLU B OE1 1 
ATOM   4737  O OE2 . GLU B 1 361 ? -52.771 16.889  56.457 1.00 61.47  ? 563 GLU B OE2 1 
ATOM   4738  N N   . GLU B 1 362 ? -50.906 21.515  52.659 1.00 56.29  ? 564 GLU B N   1 
ATOM   4739  C CA  . GLU B 1 362 ? -50.065 22.484  51.959 1.00 54.86  ? 564 GLU B CA  1 
ATOM   4740  C C   . GLU B 1 362 ? -48.622 22.578  52.469 1.00 52.77  ? 564 GLU B C   1 
ATOM   4741  O O   . GLU B 1 362 ? -47.697 22.771  51.690 1.00 52.40  ? 564 GLU B O   1 
ATOM   4742  C CB  . GLU B 1 362 ? -50.746 23.862  51.872 1.00 56.66  ? 564 GLU B CB  1 
ATOM   4743  C CG  . GLU B 1 362 ? -50.594 24.754  53.095 1.00 60.82  ? 564 GLU B CG  1 
ATOM   4744  C CD  . GLU B 1 362 ? -51.830 25.572  53.388 1.00 63.10  ? 564 GLU B CD  1 
ATOM   4745  O OE1 . GLU B 1 362 ? -51.923 26.112  54.508 1.00 63.84  ? 564 GLU B OE1 1 
ATOM   4746  O OE2 . GLU B 1 362 ? -52.708 25.669  52.506 1.00 64.26  ? 564 GLU B OE2 1 
ATOM   4747  N N   . GLU B 1 363 ? -48.443 22.433  53.777 1.00 53.01  ? 565 GLU B N   1 
ATOM   4748  C CA  . GLU B 1 363 ? -47.145 22.569  54.430 1.00 51.30  ? 565 GLU B CA  1 
ATOM   4749  C C   . GLU B 1 363 ? -46.069 21.588  53.988 1.00 47.54  ? 565 GLU B C   1 
ATOM   4750  O O   . GLU B 1 363 ? -44.904 21.947  53.882 1.00 47.40  ? 565 GLU B O   1 
ATOM   4751  C CB  . GLU B 1 363 ? -47.311 22.487  55.947 1.00 46.95  ? 565 GLU B CB  1 
ATOM   4752  C CG  . GLU B 1 363 ? -48.373 23.417  56.502 1.00 54.77  ? 565 GLU B CG  1 
ATOM   4753  C CD  . GLU B 1 363 ? -49.772 22.983  56.121 1.00 58.98  ? 565 GLU B CD  1 
ATOM   4754  O OE1 . GLU B 1 363 ? -49.900 21.998  55.366 1.00 59.15  ? 565 GLU B OE1 1 
ATOM   4755  O OE2 . GLU B 1 363 ? -50.741 23.621  56.573 1.00 61.84  ? 565 GLU B OE2 1 
ATOM   4756  N N   . ILE B 1 364 ? -46.468 20.356  53.711 1.00 47.82  ? 566 ILE B N   1 
ATOM   4757  C CA  . ILE B 1 364 ? -45.552 19.281  53.341 1.00 42.95  ? 566 ILE B CA  1 
ATOM   4758  C C   . ILE B 1 364 ? -44.923 19.339  51.949 1.00 41.65  ? 566 ILE B C   1 
ATOM   4759  O O   . ILE B 1 364 ? -44.042 18.540  51.641 1.00 40.94  ? 566 ILE B O   1 
ATOM   4760  C CB  . ILE B 1 364 ? -46.188 17.899  53.566 1.00 44.99  ? 566 ILE B CB  1 
ATOM   4761  C CG1 . ILE B 1 364 ? -47.380 17.698  52.638 1.00 43.36  ? 566 ILE B CG1 1 
ATOM   4762  C CG2 . ILE B 1 364 ? -46.612 17.746  55.015 1.00 44.55  ? 566 ILE B CG2 1 
ATOM   4763  C CD1 . ILE B 1 364 ? -48.071 16.368  52.828 1.00 41.42  ? 566 ILE B CD1 1 
ATOM   4764  N N   . LYS B 1 365 ? -45.341 20.283  51.115 1.00 41.34  ? 567 LYS B N   1 
ATOM   4765  C CA  . LYS B 1 365 ? -44.816 20.386  49.756 1.00 40.51  ? 567 LYS B CA  1 
ATOM   4766  C C   . LYS B 1 365 ? -43.299 20.575  49.693 1.00 39.53  ? 567 LYS B C   1 
ATOM   4767  O O   . LYS B 1 365 ? -42.671 20.094  48.755 1.00 39.41  ? 567 LYS B O   1 
ATOM   4768  C CB  . LYS B 1 365 ? -45.530 21.482  48.968 1.00 42.56  ? 567 LYS B CB  1 
ATOM   4769  C CG  . LYS B 1 365 ? -45.329 22.882  49.512 1.00 45.44  ? 567 LYS B CG  1 
ATOM   4770  C CD  . LYS B 1 365 ? -46.034 23.910  48.645 1.00 50.11  ? 567 LYS B CD  1 
ATOM   4771  C CE  . LYS B 1 365 ? -46.208 25.222  49.388 1.00 51.60  ? 567 LYS B CE  1 
ATOM   4772  N NZ  . LYS B 1 365 ? -47.092 25.077  50.578 1.00 54.06  ? 567 LYS B NZ  1 
ATOM   4773  N N   . THR B 1 366 ? -42.716 21.313  50.632 1.00 40.12  ? 568 THR B N   1 
ATOM   4774  C CA  . THR B 1 366 ? -41.265 21.498  50.655 1.00 38.49  ? 568 THR B CA  1 
ATOM   4775  C C   . THR B 1 366 ? -40.480 20.178  50.555 1.00 38.21  ? 568 THR B C   1 
ATOM   4776  O O   . THR B 1 366 ? -39.578 20.069  49.743 1.00 37.79  ? 568 THR B O   1 
ATOM   4777  C CB  . THR B 1 366 ? -40.806 22.301  51.886 1.00 37.80  ? 568 THR B CB  1 
ATOM   4778  O OG1 . THR B 1 366 ? -41.359 21.725  53.073 1.00 40.42  ? 568 THR B OG1 1 
ATOM   4779  C CG2 . THR B 1 366 ? -41.274 23.731  51.779 1.00 36.95  ? 568 THR B CG2 1 
ATOM   4780  N N   . THR B 1 367 ? -40.820 19.175  51.362 1.00 36.03  ? 569 THR B N   1 
ATOM   4781  C CA  . THR B 1 367 ? -40.120 17.901  51.302 1.00 35.80  ? 569 THR B CA  1 
ATOM   4782  C C   . THR B 1 367 ? -40.913 16.779  50.644 1.00 35.19  ? 569 THR B C   1 
ATOM   4783  O O   . THR B 1 367 ? -40.365 15.686  50.469 1.00 35.29  ? 569 THR B O   1 
ATOM   4784  C CB  . THR B 1 367 ? -39.706 17.462  52.714 1.00 36.37  ? 569 THR B CB  1 
ATOM   4785  O OG1 . THR B 1 367 ? -40.868 17.366  53.544 1.00 37.82  ? 569 THR B OG1 1 
ATOM   4786  C CG2 . THR B 1 367 ? -38.747 18.469  53.317 1.00 36.42  ? 569 THR B CG2 1 
ATOM   4787  N N   . ASN B 1 368 ? -42.170 17.012  50.263 1.00 35.97  ? 570 ASN B N   1 
ATOM   4788  C CA  . ASN B 1 368 ? -43.005 15.953  49.715 1.00 35.93  ? 570 ASN B CA  1 
ATOM   4789  C C   . ASN B 1 368 ? -43.478 16.298  48.311 1.00 36.89  ? 570 ASN B C   1 
ATOM   4790  O O   . ASN B 1 368 ? -43.642 17.477  47.984 1.00 38.32  ? 570 ASN B O   1 
ATOM   4791  C CB  . ASN B 1 368 ? -44.227 15.694  50.606 1.00 36.05  ? 570 ASN B CB  1 
ATOM   4792  C CG  . ASN B 1 368 ? -43.873 14.946  51.866 1.00 36.76  ? 570 ASN B CG  1 
ATOM   4793  O OD1 . ASN B 1 368 ? -42.885 14.225  51.905 1.00 37.35  ? 570 ASN B OD1 1 
ATOM   4794  N ND2 . ASN B 1 368 ? -44.680 15.108  52.902 1.00 37.47  ? 570 ASN B ND2 1 
ATOM   4795  N N   . PRO B 1 369 ? -43.694 15.299  47.457 1.00 35.24  ? 571 PRO B N   1 
ATOM   4796  C CA  . PRO B 1 369 ? -44.268 15.577  46.138 1.00 35.34  ? 571 PRO B CA  1 
ATOM   4797  C C   . PRO B 1 369 ? -45.757 15.873  46.234 1.00 35.69  ? 571 PRO B C   1 
ATOM   4798  O O   . PRO B 1 369 ? -46.416 15.554  47.224 1.00 35.80  ? 571 PRO B O   1 
ATOM   4799  C CB  . PRO B 1 369 ? -44.000 14.286  45.357 1.00 34.47  ? 571 PRO B CB  1 
ATOM   4800  C CG  . PRO B 1 369 ? -43.945 13.238  46.397 1.00 34.42  ? 571 PRO B CG  1 
ATOM   4801  C CD  . PRO B 1 369 ? -43.342 13.878  47.612 1.00 34.06  ? 571 PRO B CD  1 
ATOM   4802  N N   . VAL B 1 370 ? -46.282 16.502  45.183 1.00 39.15  ? 572 VAL B N   1 
ATOM   4803  C CA  . VAL B 1 370 ? -47.699 16.829  45.134 1.00 38.53  ? 572 VAL B CA  1 
ATOM   4804  C C   . VAL B 1 370 ? -48.499 15.561  44.869 1.00 38.95  ? 572 VAL B C   1 
ATOM   4805  O O   . VAL B 1 370 ? -48.050 14.662  44.146 1.00 38.74  ? 572 VAL B O   1 
ATOM   4806  C CB  . VAL B 1 370 ? -47.956 17.903  44.063 1.00 39.83  ? 572 VAL B CB  1 
ATOM   4807  C CG1 . VAL B 1 370 ? -49.437 18.211  43.942 1.00 39.53  ? 572 VAL B CG1 1 
ATOM   4808  C CG2 . VAL B 1 370 ? -47.175 19.165  44.389 1.00 39.42  ? 572 VAL B CG2 1 
ATOM   4809  N N   . ALA B 1 371 ? -49.691 15.478  45.465 1.00 40.58  ? 573 ALA B N   1 
ATOM   4810  C CA  . ALA B 1 371 ? -50.476 14.250  45.385 1.00 40.65  ? 573 ALA B CA  1 
ATOM   4811  C C   . ALA B 1 371 ? -50.924 13.942  43.963 1.00 41.25  ? 573 ALA B C   1 
ATOM   4812  O O   . ALA B 1 371 ? -51.036 12.769  43.589 1.00 40.61  ? 573 ALA B O   1 
ATOM   4813  C CB  . ALA B 1 371 ? -51.690 14.341  46.308 1.00 41.81  ? 573 ALA B CB  1 
ATOM   4814  N N   . THR B 1 372 ? -51.182 14.967  43.158 1.00 39.72  ? 574 THR B N   1 
ATOM   4815  C CA  . THR B 1 372 ? -51.778 14.798  41.842 1.00 40.21  ? 574 THR B CA  1 
ATOM   4816  C C   . THR B 1 372 ? -50.750 14.730  40.720 1.00 41.10  ? 574 THR B C   1 
ATOM   4817  O O   . THR B 1 372 ? -51.132 14.686  39.547 1.00 42.30  ? 574 THR B O   1 
ATOM   4818  C CB  . THR B 1 372 ? -52.771 15.927  41.576 1.00 42.64  ? 574 THR B CB  1 
ATOM   4819  O OG1 . THR B 1 372 ? -52.095 17.187  41.657 1.00 42.65  ? 574 THR B OG1 1 
ATOM   4820  C CG2 . THR B 1 372 ? -53.881 15.892  42.609 1.00 42.11  ? 574 THR B CG2 1 
ATOM   4821  N N   . GLU B 1 373 ? -49.462 14.720  41.045 1.00 36.59  ? 575 GLU B N   1 
ATOM   4822  C CA  . GLU B 1 373 ? -48.404 14.785  40.051 1.00 38.12  ? 575 GLU B CA  1 
ATOM   4823  C C   . GLU B 1 373 ? -47.601 13.492  40.022 1.00 36.68  ? 575 GLU B C   1 
ATOM   4824  O O   . GLU B 1 373 ? -47.530 12.752  41.006 1.00 36.38  ? 575 GLU B O   1 
ATOM   4825  C CB  . GLU B 1 373 ? -47.460 15.960  40.333 1.00 37.24  ? 575 GLU B CB  1 
ATOM   4826  C CG  . GLU B 1 373 ? -48.106 17.324  40.246 1.00 44.24  ? 575 GLU B CG  1 
ATOM   4827  C CD  . GLU B 1 373 ? -48.710 17.595  38.888 1.00 48.59  ? 575 GLU B CD  1 
ATOM   4828  O OE1 . GLU B 1 373 ? -48.107 17.184  37.874 1.00 51.13  ? 575 GLU B OE1 1 
ATOM   4829  O OE2 . GLU B 1 373 ? -49.785 18.226  38.834 1.00 51.24  ? 575 GLU B OE2 1 
ATOM   4830  N N   . SER B 1 374 ? -46.997 13.228  38.867 1.00 33.34  ? 576 SER B N   1 
ATOM   4831  C CA  . SER B 1 374 ? -46.009 12.171  38.767 1.00 33.24  ? 576 SER B CA  1 
ATOM   4832  C C   . SER B 1 374 ? -44.805 12.509  39.634 1.00 32.60  ? 576 SER B C   1 
ATOM   4833  O O   . SER B 1 374 ? -44.486 13.676  39.872 1.00 33.42  ? 576 SER B O   1 
ATOM   4834  C CB  . SER B 1 374 ? -45.561 11.981  37.319 1.00 30.36  ? 576 SER B CB  1 
ATOM   4835  O OG  . SER B 1 374 ? -46.629 11.542  36.505 1.00 33.76  ? 576 SER B OG  1 
ATOM   4836  N N   . TYR B 1 375 ? -44.130 11.468  40.114 1.00 26.57  ? 577 TYR B N   1 
ATOM   4837  C CA  . TYR B 1 375 ? -42.947 11.705  40.928 1.00 25.32  ? 577 TYR B CA  1 
ATOM   4838  C C   . TYR B 1 375 ? -41.831 12.330  40.099 1.00 25.73  ? 577 TYR B C   1 
ATOM   4839  O O   . TYR B 1 375 ? -41.035 13.121  40.616 1.00 25.38  ? 577 TYR B O   1 
ATOM   4840  C CB  . TYR B 1 375 ? -42.477 10.403  41.572 1.00 25.94  ? 577 TYR B CB  1 
ATOM   4841  C CG  . TYR B 1 375 ? -41.258 10.578  42.440 1.00 25.14  ? 577 TYR B CG  1 
ATOM   4842  C CD1 . TYR B 1 375 ? -41.370 11.078  43.725 1.00 25.21  ? 577 TYR B CD1 1 
ATOM   4843  C CD2 . TYR B 1 375 ? -39.992 10.266  41.967 1.00 24.17  ? 577 TYR B CD2 1 
ATOM   4844  C CE1 . TYR B 1 375 ? -40.263 11.249  44.521 1.00 25.10  ? 577 TYR B CE1 1 
ATOM   4845  C CE2 . TYR B 1 375 ? -38.879 10.435  42.756 1.00 23.61  ? 577 TYR B CE2 1 
ATOM   4846  C CZ  . TYR B 1 375 ? -39.020 10.930  44.032 1.00 24.16  ? 577 TYR B CZ  1 
ATOM   4847  O OH  . TYR B 1 375 ? -37.916 11.102  44.829 1.00 24.42  ? 577 TYR B OH  1 
ATOM   4848  N N   . GLY B 1 376 ? -41.771 12.005  38.813 1.00 25.57  ? 578 GLY B N   1 
ATOM   4849  C CA  . GLY B 1 376 ? -40.694 12.491  37.973 1.00 25.19  ? 578 GLY B CA  1 
ATOM   4850  C C   . GLY B 1 376 ? -40.640 11.716  36.673 1.00 25.68  ? 578 GLY B C   1 
ATOM   4851  O O   . GLY B 1 376 ? -41.648 11.172  36.219 1.00 25.47  ? 578 GLY B O   1 
ATOM   4852  N N   . GLN B 1 377 ? -39.449 11.680  36.081 1.00 23.84  ? 579 GLN B N   1 
ATOM   4853  C CA  . GLN B 1 377 ? -39.214 10.991  34.822 1.00 24.94  ? 579 GLN B CA  1 
ATOM   4854  C C   . GLN B 1 377 ? -38.024 10.048  34.930 1.00 24.05  ? 579 GLN B C   1 
ATOM   4855  O O   . GLN B 1 377 ? -37.069 10.304  35.667 1.00 23.97  ? 579 GLN B O   1 
ATOM   4856  C CB  . GLN B 1 377 ? -38.961 11.982  33.685 1.00 24.38  ? 579 GLN B CB  1 
ATOM   4857  C CG  . GLN B 1 377 ? -40.167 12.803  33.295 1.00 30.71  ? 579 GLN B CG  1 
ATOM   4858  C CD  . GLN B 1 377 ? -39.844 13.819  32.226 1.00 36.00  ? 579 GLN B CD  1 
ATOM   4859  O OE1 . GLN B 1 377 ? -38.709 14.279  32.114 1.00 39.19  ? 579 GLN B OE1 1 
ATOM   4860  N NE2 . GLN B 1 377 ? -40.836 14.156  31.414 1.00 37.46  ? 579 GLN B NE2 1 
ATOM   4861  N N   . VAL B 1 378 ? -38.094 8.951   34.177 1.00 23.22  ? 580 VAL B N   1 
ATOM   4862  C CA  . VAL B 1 378 ? -36.986 8.026   34.001 1.00 23.12  ? 580 VAL B CA  1 
ATOM   4863  C C   . VAL B 1 378 ? -36.840 7.740   32.516 1.00 23.87  ? 580 VAL B C   1 
ATOM   4864  O O   . VAL B 1 378 ? -37.788 7.866   31.741 1.00 23.60  ? 580 VAL B O   1 
ATOM   4865  C CB  . VAL B 1 378 ? -37.175 6.702   34.768 1.00 23.60  ? 580 VAL B CB  1 
ATOM   4866  C CG1 . VAL B 1 378 ? -37.108 6.931   36.243 1.00 24.03  ? 580 VAL B CG1 1 
ATOM   4867  C CG2 . VAL B 1 378 ? -38.505 6.074   34.399 1.00 22.54  ? 580 VAL B CG2 1 
ATOM   4868  N N   . ALA B 1 379 ? -35.634 7.341   32.128 1.00 21.93  ? 581 ALA B N   1 
ATOM   4869  C CA  . ALA B 1 379 ? -35.381 6.970   30.744 1.00 23.37  ? 581 ALA B CA  1 
ATOM   4870  C C   . ALA B 1 379 ? -35.848 5.544   30.490 1.00 24.38  ? 581 ALA B C   1 
ATOM   4871  O O   . ALA B 1 379 ? -35.605 4.644   31.295 1.00 24.02  ? 581 ALA B O   1 
ATOM   4872  C CB  . ALA B 1 379 ? -33.896 7.109   30.424 1.00 22.40  ? 581 ALA B CB  1 
ATOM   4873  N N   . THR B 1 380 ? -36.566 5.344   29.385 1.00 21.68  ? 582 THR B N   1 
ATOM   4874  C CA  . THR B 1 380 ? -37.098 4.028   29.050 1.00 22.34  ? 582 THR B CA  1 
ATOM   4875  C C   . THR B 1 380 ? -36.283 3.272   28.005 1.00 23.60  ? 582 THR B C   1 
ATOM   4876  O O   . THR B 1 380 ? -36.647 2.142   27.666 1.00 24.24  ? 582 THR B O   1 
ATOM   4877  C CB  . THR B 1 380 ? -38.552 4.140   28.582 1.00 27.52  ? 582 THR B CB  1 
ATOM   4878  O OG1 . THR B 1 380 ? -38.622 4.968   27.417 1.00 29.18  ? 582 THR B OG1 1 
ATOM   4879  C CG2 . THR B 1 380 ? -39.406 4.743   29.678 1.00 25.36  ? 582 THR B CG2 1 
ATOM   4880  N N   . ASN B 1 381 ? -35.206 3.851   27.494 1.00 21.90  ? 583 ASN B N   1 
ATOM   4881  C CA  . ASN B 1 381 ? -34.423 3.162   26.477 1.00 22.78  ? 583 ASN B CA  1 
ATOM   4882  C C   . ASN B 1 381 ? -33.004 3.676   26.383 1.00 24.05  ? 583 ASN B C   1 
ATOM   4883  O O   . ASN B 1 381 ? -32.597 4.531   27.161 1.00 24.29  ? 583 ASN B O   1 
ATOM   4884  C CB  . ASN B 1 381 ? -35.089 3.334   25.115 1.00 26.57  ? 583 ASN B CB  1 
ATOM   4885  C CG  . ASN B 1 381 ? -34.938 4.734   24.571 1.00 26.85  ? 583 ASN B CG  1 
ATOM   4886  O OD1 . ASN B 1 381 ? -34.513 5.638   25.278 1.00 28.29  ? 583 ASN B OD1 1 
ATOM   4887  N ND2 . ASN B 1 381 ? -35.258 4.913   23.303 1.00 27.08  ? 583 ASN B ND2 1 
ATOM   4888  N N   . HIS B 1 382 ? -32.249 3.140   25.427 1.00 23.52  ? 584 HIS B N   1 
ATOM   4889  C CA  . HIS B 1 382 ? -30.889 3.589   25.192 1.00 24.16  ? 584 HIS B CA  1 
ATOM   4890  C C   . HIS B 1 382 ? -30.933 4.466   23.967 1.00 23.80  ? 584 HIS B C   1 
ATOM   4891  O O   . HIS B 1 382 ? -31.338 4.018   22.903 1.00 24.00  ? 584 HIS B O   1 
ATOM   4892  C CB  . HIS B 1 382 ? -29.972 2.414   24.880 1.00 17.09  ? 584 HIS B CB  1 
ATOM   4893  C CG  . HIS B 1 382 ? -29.524 1.655   26.082 1.00 20.45  ? 584 HIS B CG  1 
ATOM   4894  N ND1 . HIS B 1 382 ? -29.270 0.304   26.051 1.00 21.99  ? 584 HIS B ND1 1 
ATOM   4895  C CD2 . HIS B 1 382 ? -29.280 2.055   27.350 1.00 22.67  ? 584 HIS B CD2 1 
ATOM   4896  C CE1 . HIS B 1 382 ? -28.888 -0.097  27.248 1.00 23.22  ? 584 HIS B CE1 1 
ATOM   4897  N NE2 . HIS B 1 382 ? -28.885 0.947   28.055 1.00 24.59  ? 584 HIS B NE2 1 
ATOM   4898  N N   . GLN B 1 383 ? -30.529 5.720   24.104 1.00 25.34  ? 585 GLN B N   1 
ATOM   4899  C CA  . GLN B 1 383 ? -30.512 6.611   22.957 1.00 24.50  ? 585 GLN B CA  1 
ATOM   4900  C C   . GLN B 1 383 ? -29.356 6.220   22.053 1.00 24.78  ? 585 GLN B C   1 
ATOM   4901  O O   . GLN B 1 383 ? -28.347 5.697   22.505 1.00 24.56  ? 585 GLN B O   1 
ATOM   4902  C CB  . GLN B 1 383 ? -30.441 8.078   23.377 1.00 25.35  ? 585 GLN B CB  1 
ATOM   4903  C CG  . GLN B 1 383 ? -29.262 8.426   24.256 1.00 23.57  ? 585 GLN B CG  1 
ATOM   4904  C CD  . GLN B 1 383 ? -28.056 8.859   23.461 1.00 22.41  ? 585 GLN B CD  1 
ATOM   4905  O OE1 . GLN B 1 383 ? -28.179 9.306   22.328 1.00 22.18  ? 585 GLN B OE1 1 
ATOM   4906  N NE2 . GLN B 1 383 ? -26.881 8.735   24.056 1.00 21.82  ? 585 GLN B NE2 1 
ATOM   4907  N N   . SER B 1 384 ? -29.518 6.453   20.765 1.00 22.22  ? 586 SER B N   1 
ATOM   4908  C CA  . SER B 1 384 ? -28.500 6.112   19.785 1.00 22.82  ? 586 SER B CA  1 
ATOM   4909  C C   . SER B 1 384 ? -28.695 6.966   18.551 1.00 23.31  ? 586 SER B C   1 
ATOM   4910  O O   . SER B 1 384 ? -29.550 7.835   18.526 1.00 22.69  ? 586 SER B O   1 
ATOM   4911  C CB  . SER B 1 384 ? -28.552 4.630   19.434 1.00 27.33  ? 586 SER B CB  1 
ATOM   4912  O OG  . SER B 1 384 ? -29.810 4.273   18.899 1.00 26.80  ? 586 SER B OG  1 
ATOM   4913  N N   . ALA B 1 385 ? -27.893 6.756   17.519 1.00 24.59  ? 587 ALA B N   1 
ATOM   4914  C CA  . ALA B 1 385 ? -28.076 7.548   16.315 1.00 25.77  ? 587 ALA B CA  1 
ATOM   4915  C C   . ALA B 1 385 ? -29.471 7.296   15.742 1.00 27.21  ? 587 ALA B C   1 
ATOM   4916  O O   . ALA B 1 385 ? -30.149 8.228   15.334 1.00 27.29  ? 587 ALA B O   1 
ATOM   4917  C CB  . ALA B 1 385 ? -27.008 7.210   15.298 1.00 27.43  ? 587 ALA B CB  1 
ATOM   4918  N N   . GLN B 1 386 ? -29.885 6.033   15.696 1.00 28.87  ? 588 GLN B N   1 
ATOM   4919  C CA  . GLN B 1 386 ? -31.216 5.645   15.243 1.00 30.97  ? 588 GLN B CA  1 
ATOM   4920  C C   . GLN B 1 386 ? -32.395 6.070   16.132 1.00 30.96  ? 588 GLN B C   1 
ATOM   4921  O O   . GLN B 1 386 ? -33.436 6.466   15.623 1.00 32.13  ? 588 GLN B O   1 
ATOM   4922  C CB  . GLN B 1 386 ? -31.282 4.135   15.018 1.00 31.32  ? 588 GLN B CB  1 
ATOM   4923  C CG  . GLN B 1 386 ? -30.448 3.644   13.849 1.00 31.32  ? 588 GLN B CG  1 
ATOM   4924  C CD  . GLN B 1 386 ? -29.012 3.369   14.236 1.00 31.32  ? 588 GLN B CD  1 
ATOM   4925  O OE1 . GLN B 1 386 ? -28.708 3.115   15.401 1.00 31.32  ? 588 GLN B OE1 1 
ATOM   4926  N NE2 . GLN B 1 386 ? -28.118 3.411   13.257 1.00 31.32  ? 588 GLN B NE2 1 
ATOM   4927  N N   . ALA B 1 387 ? -32.235 5.983   17.451 1.00 27.66  ? 589 ALA B N   1 
ATOM   4928  C CA  . ALA B 1 387 ? -33.334 6.280   18.377 1.00 25.81  ? 589 ALA B CA  1 
ATOM   4929  C C   . ALA B 1 387 ? -33.153 7.447   19.340 1.00 24.78  ? 589 ALA B C   1 
ATOM   4930  O O   . ALA B 1 387 ? -32.162 7.521   20.039 1.00 25.19  ? 589 ALA B O   1 
ATOM   4931  C CB  . ALA B 1 387 ? -33.663 5.030   19.171 1.00 27.94  ? 589 ALA B CB  1 
ATOM   4932  N N   . GLN B 1 388 ? -34.172 8.301   19.445 1.00 28.60  ? 590 GLN B N   1 
ATOM   4933  C CA  . GLN B 1 388 ? -34.146 9.466   20.316 1.00 28.53  ? 590 GLN B CA  1 
ATOM   4934  C C   . GLN B 1 388 ? -34.262 9.046   21.774 1.00 27.45  ? 590 GLN B C   1 
ATOM   4935  O O   . GLN B 1 388 ? -34.717 7.946   22.093 1.00 26.91  ? 590 GLN B O   1 
ATOM   4936  C CB  . GLN B 1 388 ? -35.283 10.423  19.969 1.00 33.70  ? 590 GLN B CB  1 
ATOM   4937  C CG  . GLN B 1 388 ? -35.180 11.043  18.596 1.00 33.70  ? 590 GLN B CG  1 
ATOM   4938  C CD  . GLN B 1 388 ? -36.356 11.940  18.280 1.00 33.70  ? 590 GLN B CD  1 
ATOM   4939  O OE1 . GLN B 1 388 ? -37.437 11.788  18.845 1.00 33.70  ? 590 GLN B OE1 1 
ATOM   4940  N NE2 . GLN B 1 388 ? -36.152 12.883  17.370 1.00 33.70  ? 590 GLN B NE2 1 
ATOM   4941  N N   . ALA B 1 389 ? -33.842 9.937   22.667 1.00 26.60  ? 591 ALA B N   1 
ATOM   4942  C CA  . ALA B 1 389 ? -33.951 9.653   24.089 1.00 26.36  ? 591 ALA B CA  1 
ATOM   4943  C C   . ALA B 1 389 ? -35.409 9.697   24.523 1.00 26.18  ? 591 ALA B C   1 
ATOM   4944  O O   . ALA B 1 389 ? -36.103 10.699  24.336 1.00 25.83  ? 591 ALA B O   1 
ATOM   4945  C CB  . ALA B 1 389 ? -33.130 10.653  24.898 1.00 23.08  ? 591 ALA B CB  1 
ATOM   4946  N N   . GLN B 1 390 ? -35.870 8.601   25.113 1.00 26.41  ? 592 GLN B N   1 
ATOM   4947  C CA  . GLN B 1 390 ? -37.257 8.460   25.519 1.00 26.91  ? 592 GLN B CA  1 
ATOM   4948  C C   . GLN B 1 390 ? -37.346 8.397   27.033 1.00 26.71  ? 592 GLN B C   1 
ATOM   4949  O O   . GLN B 1 390 ? -36.567 7.702   27.689 1.00 26.13  ? 592 GLN B O   1 
ATOM   4950  C CB  . GLN B 1 390 ? -37.889 7.208   24.918 1.00 30.63  ? 592 GLN B CB  1 
ATOM   4951  C CG  . GLN B 1 390 ? -37.997 7.239   23.413 1.00 30.63  ? 592 GLN B CG  1 
ATOM   4952  C CD  . GLN B 1 390 ? -38.531 5.943   22.855 1.00 30.63  ? 592 GLN B CD  1 
ATOM   4953  O OE1 . GLN B 1 390 ? -38.418 4.893   23.484 1.00 30.63  ? 592 GLN B OE1 1 
ATOM   4954  N NE2 . GLN B 1 390 ? -39.113 6.007   21.666 1.00 30.63  ? 592 GLN B NE2 1 
ATOM   4955  N N   . THR B 1 391 ? -38.305 9.132   27.584 1.00 27.40  ? 593 THR B N   1 
ATOM   4956  C CA  . THR B 1 391 ? -38.582 9.090   29.008 1.00 27.68  ? 593 THR B CA  1 
ATOM   4957  C C   . THR B 1 391 ? -39.970 8.507   29.233 1.00 26.15  ? 593 THR B C   1 
ATOM   4958  O O   . THR B 1 391 ? -40.717 8.231   28.292 1.00 26.26  ? 593 THR B O   1 
ATOM   4959  C CB  . THR B 1 391 ? -38.483 10.480  29.649 1.00 30.14  ? 593 THR B CB  1 
ATOM   4960  O OG1 . THR B 1 391 ? -39.396 11.374  29.002 1.00 32.58  ? 593 THR B OG1 1 
ATOM   4961  C CG2 . THR B 1 391 ? -37.072 11.027  29.537 1.00 29.64  ? 593 THR B CG2 1 
ATOM   4962  N N   . GLY B 1 392 ? -40.308 8.334   30.498 1.00 26.88  ? 594 GLY B N   1 
ATOM   4963  C CA  . GLY B 1 392 ? -41.639 7.903   30.882 1.00 24.96  ? 594 GLY B CA  1 
ATOM   4964  C C   . GLY B 1 392 ? -41.913 8.375   32.286 1.00 23.92  ? 594 GLY B C   1 
ATOM   4965  O O   . GLY B 1 392 ? -40.993 8.560   33.086 1.00 24.01  ? 594 GLY B O   1 
ATOM   4966  N N   . TRP B 1 393 ? -43.187 8.560   32.593 1.00 27.94  ? 595 TRP B N   1 
ATOM   4967  C CA  . TRP B 1 393 ? -43.548 9.189   33.853 1.00 27.26  ? 595 TRP B CA  1 
ATOM   4968  C C   . TRP B 1 393 ? -43.548 8.161   34.971 1.00 25.54  ? 595 TRP B C   1 
ATOM   4969  O O   . TRP B 1 393 ? -43.843 6.984   34.744 1.00 25.51  ? 595 TRP B O   1 
ATOM   4970  C CB  . TRP B 1 393 ? -44.908 9.865   33.738 1.00 25.38  ? 595 TRP B CB  1 
ATOM   4971  C CG  . TRP B 1 393 ? -44.901 11.020  32.798 1.00 29.18  ? 595 TRP B CG  1 
ATOM   4972  C CD1 . TRP B 1 393 ? -45.348 11.031  31.511 1.00 29.87  ? 595 TRP B CD1 1 
ATOM   4973  C CD2 . TRP B 1 393 ? -44.377 12.326  33.052 1.00 31.52  ? 595 TRP B CD2 1 
ATOM   4974  N NE1 . TRP B 1 393 ? -45.160 12.271  30.956 1.00 31.34  ? 595 TRP B NE1 1 
ATOM   4975  C CE2 . TRP B 1 393 ? -44.562 13.084  31.882 1.00 31.86  ? 595 TRP B CE2 1 
ATOM   4976  C CE3 . TRP B 1 393 ? -43.779 12.930  34.159 1.00 33.52  ? 595 TRP B CE3 1 
ATOM   4977  C CZ2 . TRP B 1 393 ? -44.175 14.414  31.788 1.00 32.63  ? 595 TRP B CZ2 1 
ATOM   4978  C CZ3 . TRP B 1 393 ? -43.395 14.248  34.065 1.00 34.95  ? 595 TRP B CZ3 1 
ATOM   4979  C CH2 . TRP B 1 393 ? -43.593 14.977  32.888 1.00 34.27  ? 595 TRP B CH2 1 
ATOM   4980  N N   . VAL B 1 394 ? -43.201 8.602   36.175 1.00 28.19  ? 596 VAL B N   1 
ATOM   4981  C CA  . VAL B 1 394 ? -43.252 7.747   37.353 1.00 26.56  ? 596 VAL B CA  1 
ATOM   4982  C C   . VAL B 1 394 ? -44.513 8.110   38.124 1.00 26.72  ? 596 VAL B C   1 
ATOM   4983  O O   . VAL B 1 394 ? -44.581 9.160   38.766 1.00 26.20  ? 596 VAL B O   1 
ATOM   4984  C CB  . VAL B 1 394 ? -42.002 7.915   38.222 1.00 25.13  ? 596 VAL B CB  1 
ATOM   4985  C CG1 . VAL B 1 394 ? -42.162 7.169   39.529 1.00 23.68  ? 596 VAL B CG1 1 
ATOM   4986  C CG2 . VAL B 1 394 ? -40.778 7.428   37.474 1.00 23.06  ? 596 VAL B CG2 1 
ATOM   4987  N N   . GLN B 1 395 ? -45.514 7.234   38.068 1.00 28.34  ? 597 GLN B N   1 
ATOM   4988  C CA  . GLN B 1 395 ? -46.773 7.509   38.743 1.00 29.08  ? 597 GLN B CA  1 
ATOM   4989  C C   . GLN B 1 395 ? -46.713 7.155   40.220 1.00 29.41  ? 597 GLN B C   1 
ATOM   4990  O O   . GLN B 1 395 ? -47.210 7.917   41.055 1.00 30.33  ? 597 GLN B O   1 
ATOM   4991  C CB  . GLN B 1 395 ? -47.902 6.750   38.054 1.00 30.87  ? 597 GLN B CB  1 
ATOM   4992  C CG  . GLN B 1 395 ? -48.068 7.122   36.595 1.00 32.22  ? 597 GLN B CG  1 
ATOM   4993  C CD  . GLN B 1 395 ? -48.292 8.601   36.394 1.00 31.04  ? 597 GLN B CD  1 
ATOM   4994  O OE1 . GLN B 1 395 ? -48.953 9.251   37.198 1.00 32.47  ? 597 GLN B OE1 1 
ATOM   4995  N NE2 . GLN B 1 395 ? -47.758 9.139   35.307 1.00 30.59  ? 597 GLN B NE2 1 
ATOM   4996  N N   . ASN B 1 396 ? -46.121 6.014   40.560 1.00 27.10  ? 598 ASN B N   1 
ATOM   4997  C CA  . ASN B 1 396 ? -45.884 5.648   41.947 1.00 26.93  ? 598 ASN B CA  1 
ATOM   4998  C C   . ASN B 1 396 ? -44.401 5.391   42.140 1.00 26.55  ? 598 ASN B C   1 
ATOM   4999  O O   . ASN B 1 396 ? -43.747 4.801   41.276 1.00 27.75  ? 598 ASN B O   1 
ATOM   5000  C CB  . ASN B 1 396 ? -46.681 4.409   42.366 1.00 28.88  ? 598 ASN B CB  1 
ATOM   5001  C CG  . ASN B 1 396 ? -46.323 3.180   41.556 1.00 29.85  ? 598 ASN B CG  1 
ATOM   5002  O OD1 . ASN B 1 396 ? -45.810 3.281   40.444 1.00 30.65  ? 598 ASN B OD1 1 
ATOM   5003  N ND2 . ASN B 1 396 ? -46.553 2.010   42.131 1.00 29.42  ? 598 ASN B ND2 1 
ATOM   5004  N N   . GLN B 1 397 ? -43.871 5.840   43.272 1.00 28.12  ? 599 GLN B N   1 
ATOM   5005  C CA  . GLN B 1 397 ? -42.464 5.639   43.592 1.00 26.20  ? 599 GLN B CA  1 
ATOM   5006  C C   . GLN B 1 397 ? -42.346 5.231   45.047 1.00 26.15  ? 599 GLN B C   1 
ATOM   5007  O O   . GLN B 1 397 ? -42.807 5.952   45.935 1.00 26.69  ? 599 GLN B O   1 
ATOM   5008  C CB  . GLN B 1 397 ? -41.643 6.900   43.321 1.00 25.83  ? 599 GLN B CB  1 
ATOM   5009  C CG  . GLN B 1 397 ? -40.163 6.728   43.593 1.00 25.25  ? 599 GLN B CG  1 
ATOM   5010  C CD  . GLN B 1 397 ? -39.539 5.641   42.746 1.00 25.58  ? 599 GLN B CD  1 
ATOM   5011  O OE1 . GLN B 1 397 ? -39.599 5.682   41.520 1.00 27.72  ? 599 GLN B OE1 1 
ATOM   5012  N NE2 . GLN B 1 397 ? -38.929 4.663   43.399 1.00 24.66  ? 599 GLN B NE2 1 
ATOM   5013  N N   . GLY B 1 398 ? -41.726 4.081   45.288 1.00 26.17  ? 600 GLY B N   1 
ATOM   5014  C CA  . GLY B 1 398 ? -41.486 3.626   46.635 1.00 24.75  ? 600 GLY B CA  1 
ATOM   5015  C C   . GLY B 1 398 ? -40.336 4.363   47.282 1.00 24.56  ? 600 GLY B C   1 
ATOM   5016  O O   . GLY B 1 398 ? -39.769 5.308   46.736 1.00 24.12  ? 600 GLY B O   1 
ATOM   5017  N N   . ILE B 1 399 ? -39.985 3.906   48.483 1.00 24.37  ? 601 ILE B N   1 
ATOM   5018  C CA  . ILE B 1 399 ? -38.873 4.501   49.208 1.00 23.65  ? 601 ILE B CA  1 
ATOM   5019  C C   . ILE B 1 399 ? -37.578 4.305   48.432 1.00 23.23  ? 601 ILE B C   1 
ATOM   5020  O O   . ILE B 1 399 ? -37.336 3.244   47.848 1.00 23.90  ? 601 ILE B O   1 
ATOM   5021  C CB  . ILE B 1 399 ? -38.782 3.890   50.617 1.00 23.31  ? 601 ILE B CB  1 
ATOM   5022  C CG1 . ILE B 1 399 ? -40.052 4.179   51.408 1.00 23.71  ? 601 ILE B CG1 1 
ATOM   5023  C CG2 . ILE B 1 399 ? -37.611 4.450   51.355 1.00 24.77  ? 601 ILE B CG2 1 
ATOM   5024  C CD1 . ILE B 1 399 ? -40.292 5.643   51.633 1.00 22.57  ? 601 ILE B CD1 1 
ATOM   5025  N N   . LEU B 1 400 ? -36.749 5.343   48.407 1.00 24.60  ? 602 LEU B N   1 
ATOM   5026  C CA  . LEU B 1 400 ? -35.389 5.283   47.899 1.00 24.05  ? 602 LEU B CA  1 
ATOM   5027  C C   . LEU B 1 400 ? -34.432 5.781   48.968 1.00 25.12  ? 602 LEU B C   1 
ATOM   5028  O O   . LEU B 1 400 ? -34.813 6.601   49.809 1.00 24.79  ? 602 LEU B O   1 
ATOM   5029  C CB  . LEU B 1 400 ? -35.217 6.128   46.631 1.00 23.19  ? 602 LEU B CB  1 
ATOM   5030  C CG  . LEU B 1 400 ? -35.928 5.642   45.373 1.00 22.46  ? 602 LEU B CG  1 
ATOM   5031  C CD1 . LEU B 1 400 ? -35.826 6.675   44.273 1.00 21.93  ? 602 LEU B CD1 1 
ATOM   5032  C CD2 . LEU B 1 400 ? -35.307 4.347   44.918 1.00 21.42  ? 602 LEU B CD2 1 
ATOM   5033  N N   . PRO B 1 401 ? -33.194 5.290   48.979 1.00 25.31  ? 603 PRO B N   1 
ATOM   5034  C CA  . PRO B 1 401 ? -32.196 5.849   49.897 1.00 25.50  ? 603 PRO B CA  1 
ATOM   5035  C C   . PRO B 1 401 ? -31.953 7.317   49.585 1.00 25.71  ? 603 PRO B C   1 
ATOM   5036  O O   . PRO B 1 401 ? -31.666 7.689   48.446 1.00 26.12  ? 603 PRO B O   1 
ATOM   5037  C CB  . PRO B 1 401 ? -30.953 4.998   49.626 1.00 21.79  ? 603 PRO B CB  1 
ATOM   5038  C CG  . PRO B 1 401 ? -31.487 3.723   49.088 1.00 24.27  ? 603 PRO B CG  1 
ATOM   5039  C CD  . PRO B 1 401 ? -32.681 4.106   48.272 1.00 22.93  ? 603 PRO B CD  1 
ATOM   5040  N N   . GLY B 1 402 ? -32.057 8.152   50.613 1.00 27.83  ? 604 GLY B N   1 
ATOM   5041  C CA  . GLY B 1 402 ? -31.925 9.581   50.450 1.00 26.80  ? 604 GLY B CA  1 
ATOM   5042  C C   . GLY B 1 402 ? -33.225 10.356  50.470 1.00 26.65  ? 604 GLY B C   1 
ATOM   5043  O O   . GLY B 1 402 ? -33.187 11.588  50.394 1.00 26.89  ? 604 GLY B O   1 
ATOM   5044  N N   . MET B 1 403 ? -34.368 9.684   50.562 1.00 26.89  ? 605 MET B N   1 
ATOM   5045  C CA  . MET B 1 403 ? -35.641 10.381  50.633 1.00 25.57  ? 605 MET B CA  1 
ATOM   5046  C C   . MET B 1 403 ? -35.904 10.911  52.033 1.00 24.92  ? 605 MET B C   1 
ATOM   5047  O O   . MET B 1 403 ? -35.430 10.356  53.027 1.00 25.50  ? 605 MET B O   1 
ATOM   5048  C CB  . MET B 1 403 ? -36.794 9.474   50.209 1.00 24.54  ? 605 MET B CB  1 
ATOM   5049  C CG  . MET B 1 403 ? -36.897 9.240   48.723 1.00 25.29  ? 605 MET B CG  1 
ATOM   5050  S SD  . MET B 1 403 ? -38.305 8.196   48.329 1.00 27.96  ? 605 MET B SD  1 
ATOM   5051  C CE  . MET B 1 403 ? -38.228 8.199   46.545 1.00 28.24  ? 605 MET B CE  1 
ATOM   5052  N N   . VAL B 1 404 ? -36.660 12.005  52.098 1.00 26.81  ? 606 VAL B N   1 
ATOM   5053  C CA  . VAL B 1 404 ? -37.168 12.568  53.340 1.00 26.35  ? 606 VAL B CA  1 
ATOM   5054  C C   . VAL B 1 404 ? -38.628 12.927  53.111 1.00 26.45  ? 606 VAL B C   1 
ATOM   5055  O O   . VAL B 1 404 ? -39.041 13.217  51.985 1.00 28.68  ? 606 VAL B O   1 
ATOM   5056  C CB  . VAL B 1 404 ? -36.365 13.805  53.800 1.00 26.56  ? 606 VAL B CB  1 
ATOM   5057  C CG1 . VAL B 1 404 ? -34.930 13.429  54.111 1.00 30.30  ? 606 VAL B CG1 1 
ATOM   5058  C CG2 . VAL B 1 404 ? -36.408 14.880  52.747 1.00 25.64  ? 606 VAL B CG2 1 
ATOM   5059  N N   . TRP B 1 405 ? -39.417 12.897  54.179 1.00 29.64  ? 607 TRP B N   1 
ATOM   5060  C CA  . TRP B 1 405 ? -40.838 13.183  54.043 1.00 29.56  ? 607 TRP B CA  1 
ATOM   5061  C C   . TRP B 1 405 ? -41.374 13.754  55.347 1.00 30.30  ? 607 TRP B C   1 
ATOM   5062  O O   . TRP B 1 405 ? -40.759 13.632  56.407 1.00 29.96  ? 607 TRP B O   1 
ATOM   5063  C CB  . TRP B 1 405 ? -41.625 11.934  53.624 1.00 27.62  ? 607 TRP B CB  1 
ATOM   5064  C CG  . TRP B 1 405 ? -41.506 10.769  54.559 1.00 28.12  ? 607 TRP B CG  1 
ATOM   5065  C CD1 . TRP B 1 405 ? -42.306 10.488  55.627 1.00 29.04  ? 607 TRP B CD1 1 
ATOM   5066  C CD2 . TRP B 1 405 ? -40.547 9.709   54.488 1.00 28.09  ? 607 TRP B CD2 1 
ATOM   5067  N NE1 . TRP B 1 405 ? -41.892 9.330   56.236 1.00 28.56  ? 607 TRP B NE1 1 
ATOM   5068  C CE2 . TRP B 1 405 ? -40.815 8.831   55.554 1.00 28.97  ? 607 TRP B CE2 1 
ATOM   5069  C CE3 . TRP B 1 405 ? -39.483 9.422   53.631 1.00 27.41  ? 607 TRP B CE3 1 
ATOM   5070  C CZ2 . TRP B 1 405 ? -40.058 7.688   55.785 1.00 28.49  ? 607 TRP B CZ2 1 
ATOM   5071  C CZ3 . TRP B 1 405 ? -38.735 8.289   53.862 1.00 28.96  ? 607 TRP B CZ3 1 
ATOM   5072  C CH2 . TRP B 1 405 ? -39.024 7.436   54.930 1.00 28.76  ? 607 TRP B CH2 1 
ATOM   5073  N N   . GLN B 1 406 ? -42.529 14.401  55.241 1.00 34.28  ? 608 GLN B N   1 
ATOM   5074  C CA  . GLN B 1 406 ? -43.314 14.848  56.379 1.00 35.52  ? 608 GLN B CA  1 
ATOM   5075  C C   . GLN B 1 406 ? -44.559 13.983  56.497 1.00 35.98  ? 608 GLN B C   1 
ATOM   5076  O O   . GLN B 1 406 ? -45.196 13.646  55.496 1.00 35.17  ? 608 GLN B O   1 
ATOM   5077  C CB  . GLN B 1 406 ? -43.727 16.317  56.236 1.00 31.19  ? 608 GLN B CB  1 
ATOM   5078  C CG  . GLN B 1 406 ? -42.606 17.324  56.371 1.00 36.83  ? 608 GLN B CG  1 
ATOM   5079  C CD  . GLN B 1 406 ? -42.021 17.354  57.764 1.00 40.48  ? 608 GLN B CD  1 
ATOM   5080  O OE1 . GLN B 1 406 ? -42.742 17.280  58.755 1.00 43.76  ? 608 GLN B OE1 1 
ATOM   5081  N NE2 . GLN B 1 406 ? -40.707 17.462  57.847 1.00 36.76  ? 608 GLN B NE2 1 
ATOM   5082  N N   . ASP B 1 407 ? -44.903 13.627  57.729 1.00 40.38  ? 609 ASP B N   1 
ATOM   5083  C CA  . ASP B 1 407 ? -46.112 12.859  57.966 1.00 41.16  ? 609 ASP B CA  1 
ATOM   5084  C C   . ASP B 1 407 ? -47.335 13.753  57.798 1.00 40.25  ? 609 ASP B C   1 
ATOM   5085  O O   . ASP B 1 407 ? -47.235 14.951  57.522 1.00 38.80  ? 609 ASP B O   1 
ATOM   5086  C CB  . ASP B 1 407 ? -46.080 12.225  59.353 1.00 35.88  ? 609 ASP B CB  1 
ATOM   5087  C CG  . ASP B 1 407 ? -45.058 11.121  59.460 1.00 41.25  ? 609 ASP B CG  1 
ATOM   5088  O OD1 . ASP B 1 407 ? -44.595 10.639  58.406 1.00 42.25  ? 609 ASP B OD1 1 
ATOM   5089  O OD2 . ASP B 1 407 ? -44.713 10.738  60.597 1.00 43.29  ? 609 ASP B OD2 1 
ATOM   5090  N N   . ARG B 1 408 ? -48.511 13.165  57.970 1.00 44.95  ? 610 ARG B N   1 
ATOM   5091  C CA  . ARG B 1 408 ? -49.737 13.930  57.846 1.00 45.29  ? 610 ARG B CA  1 
ATOM   5092  C C   . ARG B 1 408 ? -50.003 14.709  59.126 1.00 45.31  ? 610 ARG B C   1 
ATOM   5093  O O   . ARG B 1 408 ? -49.881 14.188  60.237 1.00 44.75  ? 610 ARG B O   1 
ATOM   5094  C CB  . ARG B 1 408 ? -50.914 13.013  57.528 1.00 43.47  ? 610 ARG B CB  1 
ATOM   5095  C CG  . ARG B 1 408 ? -52.206 13.749  57.265 1.00 44.89  ? 610 ARG B CG  1 
ATOM   5096  C CD  . ARG B 1 408 ? -53.297 12.777  56.899 1.00 47.02  ? 610 ARG B CD  1 
ATOM   5097  N NE  . ARG B 1 408 ? -52.956 12.066  55.673 1.00 49.92  ? 610 ARG B NE  1 
ATOM   5098  C CZ  . ARG B 1 408 ? -53.167 12.542  54.453 1.00 51.20  ? 610 ARG B CZ  1 
ATOM   5099  N NH1 . ARG B 1 408 ? -53.722 13.735  54.292 1.00 51.97  ? 610 ARG B NH1 1 
ATOM   5100  N NH2 . ARG B 1 408 ? -52.821 11.829  53.392 1.00 52.21  ? 610 ARG B NH2 1 
ATOM   5101  N N   . ASP B 1 409 ? -50.355 15.977  58.955 1.00 50.15  ? 611 ASP B N   1 
ATOM   5102  C CA  . ASP B 1 409 ? -50.622 16.854  60.078 1.00 50.59  ? 611 ASP B CA  1 
ATOM   5103  C C   . ASP B 1 409 ? -51.843 16.361  60.849 1.00 50.34  ? 611 ASP B C   1 
ATOM   5104  O O   . ASP B 1 409 ? -52.860 15.966  60.272 1.00 50.14  ? 611 ASP B O   1 
ATOM   5105  C CB  . ASP B 1 409 ? -50.827 18.285  59.579 1.00 51.85  ? 611 ASP B CB  1 
ATOM   5106  C CG  . ASP B 1 409 ? -50.901 19.298  60.699 1.00 54.19  ? 611 ASP B CG  1 
ATOM   5107  O OD1 . ASP B 1 409 ? -50.757 18.916  61.877 1.00 56.74  ? 611 ASP B OD1 1 
ATOM   5108  O OD2 . ASP B 1 409 ? -51.083 20.491  60.389 1.00 53.23  ? 611 ASP B OD2 1 
ATOM   5109  N N   . VAL B 1 410 ? -51.721 16.353  62.172 1.00 51.40  ? 612 VAL B N   1 
ATOM   5110  C CA  . VAL B 1 410 ? -52.819 15.966  63.045 1.00 50.02  ? 612 VAL B CA  1 
ATOM   5111  C C   . VAL B 1 410 ? -53.785 17.136  63.123 1.00 48.85  ? 612 VAL B C   1 
ATOM   5112  O O   . VAL B 1 410 ? -53.403 18.298  62.945 1.00 48.09  ? 612 VAL B O   1 
ATOM   5113  C CB  . VAL B 1 410 ? -52.343 15.557  64.453 1.00 45.01  ? 612 VAL B CB  1 
ATOM   5114  C CG1 . VAL B 1 410 ? -51.412 14.364  64.367 1.00 44.37  ? 612 VAL B CG1 1 
ATOM   5115  C CG2 . VAL B 1 410 ? -51.673 16.723  65.150 1.00 47.82  ? 612 VAL B CG2 1 
ATOM   5116  N N   . TYR B 1 411 ? -55.046 16.825  63.387 1.00 52.94  ? 613 TYR B N   1 
ATOM   5117  C CA  . TYR B 1 411 ? -56.077 17.842  63.473 1.00 52.56  ? 613 TYR B CA  1 
ATOM   5118  C C   . TYR B 1 411 ? -56.768 17.766  64.823 1.00 52.23  ? 613 TYR B C   1 
ATOM   5119  O O   . TYR B 1 411 ? -56.676 16.766  65.539 1.00 53.59  ? 613 TYR B O   1 
ATOM   5120  C CB  . TYR B 1 411 ? -57.089 17.697  62.332 1.00 48.66  ? 613 TYR B CB  1 
ATOM   5121  C CG  . TYR B 1 411 ? -56.467 17.962  60.983 1.00 52.16  ? 613 TYR B CG  1 
ATOM   5122  C CD1 . TYR B 1 411 ? -56.392 19.250  60.477 1.00 53.56  ? 613 TYR B CD1 1 
ATOM   5123  C CD2 . TYR B 1 411 ? -55.931 16.931  60.229 1.00 53.23  ? 613 TYR B CD2 1 
ATOM   5124  C CE1 . TYR B 1 411 ? -55.813 19.500  59.252 1.00 55.62  ? 613 TYR B CE1 1 
ATOM   5125  C CE2 . TYR B 1 411 ? -55.354 17.172  59.003 1.00 56.73  ? 613 TYR B CE2 1 
ATOM   5126  C CZ  . TYR B 1 411 ? -55.297 18.457  58.520 1.00 57.21  ? 613 TYR B CZ  1 
ATOM   5127  O OH  . TYR B 1 411 ? -54.719 18.701  57.298 1.00 59.17  ? 613 TYR B OH  1 
ATOM   5128  N N   . LEU B 1 412 ? -57.445 18.859  65.174 1.00 54.54  ? 614 LEU B N   1 
ATOM   5129  C CA  . LEU B 1 412 ? -58.162 18.904  66.441 1.00 54.00  ? 614 LEU B CA  1 
ATOM   5130  C C   . LEU B 1 412 ? -59.331 17.929  66.432 1.00 55.09  ? 614 LEU B C   1 
ATOM   5131  O O   . LEU B 1 412 ? -59.638 17.304  67.453 1.00 56.38  ? 614 LEU B O   1 
ATOM   5132  C CB  . LEU B 1 412 ? -58.642 20.328  66.714 1.00 52.38  ? 614 LEU B CB  1 
ATOM   5133  C CG  . LEU B 1 412 ? -59.167 20.634  68.114 1.00 52.12  ? 614 LEU B CG  1 
ATOM   5134  C CD1 . LEU B 1 412 ? -58.435 19.797  69.147 1.00 52.28  ? 614 LEU B CD1 1 
ATOM   5135  C CD2 . LEU B 1 412 ? -58.996 22.106  68.421 1.00 50.64  ? 614 LEU B CD2 1 
ATOM   5136  N N   . GLN B 1 413 ? -59.989 17.780  65.283 1.00 53.91  ? 615 GLN B N   1 
ATOM   5137  C CA  . GLN B 1 413 ? -61.045 16.792  65.128 1.00 53.76  ? 615 GLN B CA  1 
ATOM   5138  C C   . GLN B 1 413 ? -60.514 15.411  64.772 1.00 53.33  ? 615 GLN B C   1 
ATOM   5139  O O   . GLN B 1 413 ? -61.295 14.456  64.740 1.00 53.92  ? 615 GLN B O   1 
ATOM   5140  C CB  . GLN B 1 413 ? -62.035 17.235  64.048 1.00 51.61  ? 615 GLN B CB  1 
ATOM   5141  C CG  . GLN B 1 413 ? -62.758 18.532  64.336 1.00 57.01  ? 615 GLN B CG  1 
ATOM   5142  C CD  . GLN B 1 413 ? -61.965 19.744  63.899 1.00 59.90  ? 615 GLN B CD  1 
ATOM   5143  O OE1 . GLN B 1 413 ? -60.857 19.618  63.384 1.00 58.65  ? 615 GLN B OE1 1 
ATOM   5144  N NE2 . GLN B 1 413 ? -62.532 20.926  64.097 1.00 62.49  ? 615 GLN B NE2 1 
ATOM   5145  N N   . GLY B 1 414 ? -59.219 15.281  64.503 1.00 52.01  ? 616 GLY B N   1 
ATOM   5146  C CA  . GLY B 1 414 ? -58.658 14.040  64.029 1.00 50.37  ? 616 GLY B CA  1 
ATOM   5147  C C   . GLY B 1 414 ? -58.226 13.112  65.145 1.00 49.33  ? 616 GLY B C   1 
ATOM   5148  O O   . GLY B 1 414 ? -58.299 13.445  66.332 1.00 49.07  ? 616 GLY B O   1 
ATOM   5149  N N   . PRO B 1 415 ? -57.754 11.925  64.774 1.00 50.25  ? 617 PRO B N   1 
ATOM   5150  C CA  . PRO B 1 415 ? -57.376 10.929  65.780 1.00 50.44  ? 617 PRO B CA  1 
ATOM   5151  C C   . PRO B 1 415 ? -56.068 11.285  66.466 1.00 50.81  ? 617 PRO B C   1 
ATOM   5152  O O   . PRO B 1 415 ? -55.283 12.108  65.991 1.00 50.85  ? 617 PRO B O   1 
ATOM   5153  C CB  . PRO B 1 415 ? -57.238 9.644   64.962 1.00 47.13  ? 617 PRO B CB  1 
ATOM   5154  C CG  . PRO B 1 415 ? -56.847 10.121  63.609 1.00 47.85  ? 617 PRO B CG  1 
ATOM   5155  C CD  . PRO B 1 415 ? -57.562 11.426  63.402 1.00 46.46  ? 617 PRO B CD  1 
ATOM   5156  N N   . ILE B 1 416 ? -55.837 10.636  67.605 1.00 49.23  ? 618 ILE B N   1 
ATOM   5157  C CA  . ILE B 1 416 ? -54.631 10.876  68.389 1.00 47.46  ? 618 ILE B CA  1 
ATOM   5158  C C   . ILE B 1 416 ? -53.618 9.771   68.119 1.00 48.29  ? 618 ILE B C   1 
ATOM   5159  O O   . ILE B 1 416 ? -52.531 10.027  67.594 1.00 48.76  ? 618 ILE B O   1 
ATOM   5160  C CB  . ILE B 1 416 ? -54.941 10.974  69.892 1.00 50.97  ? 618 ILE B CB  1 
ATOM   5161  C CG1 . ILE B 1 416 ? -55.863 12.156  70.176 1.00 50.21  ? 618 ILE B CG1 1 
ATOM   5162  C CG2 . ILE B 1 416 ? -53.657 11.138  70.680 1.00 47.44  ? 618 ILE B CG2 1 
ATOM   5163  C CD1 . ILE B 1 416 ? -56.373 12.190  71.592 1.00 48.77  ? 618 ILE B CD1 1 
ATOM   5164  N N   . TRP B 1 417 ? -53.963 8.540   68.479 1.00 50.36  ? 619 TRP B N   1 
ATOM   5165  C CA  . TRP B 1 417 ? -53.075 7.398   68.336 1.00 50.62  ? 619 TRP B CA  1 
ATOM   5166  C C   . TRP B 1 417 ? -53.732 6.336   67.465 1.00 51.19  ? 619 TRP B C   1 
ATOM   5167  O O   . TRP B 1 417 ? -54.938 6.359   67.214 1.00 50.73  ? 619 TRP B O   1 
ATOM   5168  C CB  . TRP B 1 417 ? -52.721 6.786   69.697 1.00 50.65  ? 619 TRP B CB  1 
ATOM   5169  C CG  . TRP B 1 417 ? -53.909 6.212   70.411 1.00 51.93  ? 619 TRP B CG  1 
ATOM   5170  C CD1 . TRP B 1 417 ? -54.428 4.961   70.256 1.00 53.24  ? 619 TRP B CD1 1 
ATOM   5171  C CD2 . TRP B 1 417 ? -54.704 6.852   71.415 1.00 51.95  ? 619 TRP B CD2 1 
ATOM   5172  N NE1 . TRP B 1 417 ? -55.509 4.790   71.081 1.00 53.93  ? 619 TRP B NE1 1 
ATOM   5173  C CE2 . TRP B 1 417 ? -55.698 5.936   71.806 1.00 53.03  ? 619 TRP B CE2 1 
ATOM   5174  C CE3 . TRP B 1 417 ? -54.676 8.111   72.017 1.00 50.60  ? 619 TRP B CE3 1 
ATOM   5175  C CZ2 . TRP B 1 417 ? -56.655 6.241   72.769 1.00 53.54  ? 619 TRP B CZ2 1 
ATOM   5176  C CZ3 . TRP B 1 417 ? -55.626 8.412   72.969 1.00 52.07  ? 619 TRP B CZ3 1 
ATOM   5177  C CH2 . TRP B 1 417 ? -56.602 7.482   73.337 1.00 53.61  ? 619 TRP B CH2 1 
ATOM   5178  N N   . ALA B 1 418 ? -52.912 5.398   67.002 1.00 45.87  ? 620 ALA B N   1 
ATOM   5179  C CA  . ALA B 1 418 ? -53.401 4.198   66.343 1.00 47.05  ? 620 ALA B CA  1 
ATOM   5180  C C   . ALA B 1 418 ? -52.597 3.009   66.842 1.00 48.03  ? 620 ALA B C   1 
ATOM   5181  O O   . ALA B 1 418 ? -51.510 3.161   67.403 1.00 47.89  ? 620 ALA B O   1 
ATOM   5182  C CB  . ALA B 1 418 ? -53.308 4.304   64.820 1.00 42.81  ? 620 ALA B CB  1 
ATOM   5183  N N   . LYS B 1 419 ? -53.148 1.816   66.643 1.00 45.22  ? 621 LYS B N   1 
ATOM   5184  C CA  . LYS B 1 419 ? -52.473 0.589   67.038 1.00 45.80  ? 621 LYS B CA  1 
ATOM   5185  C C   . LYS B 1 419 ? -51.708 0.027   65.850 1.00 46.66  ? 621 LYS B C   1 
ATOM   5186  O O   . LYS B 1 419 ? -52.308 -0.348  64.839 1.00 46.69  ? 621 LYS B O   1 
ATOM   5187  C CB  . LYS B 1 419 ? -53.465 -0.450  67.558 1.00 45.66  ? 621 LYS B CB  1 
ATOM   5188  C CG  . LYS B 1 419 ? -52.785 -1.699  68.091 1.00 47.03  ? 621 LYS B CG  1 
ATOM   5189  C CD  . LYS B 1 419 ? -53.770 -2.650  68.737 1.00 49.07  ? 621 LYS B CD  1 
ATOM   5190  C CE  . LYS B 1 419 ? -53.059 -3.877  69.278 1.00 51.98  ? 621 LYS B CE  1 
ATOM   5191  N NZ  . LYS B 1 419 ? -52.523 -4.739  68.189 1.00 54.67  ? 621 LYS B NZ  1 
ATOM   5192  N N   . ILE B 1 420 ? -50.391 -0.022  65.975 1.00 43.10  ? 622 ILE B N   1 
ATOM   5193  C CA  . ILE B 1 420 ? -49.557 -0.601  64.919 1.00 43.61  ? 622 ILE B CA  1 
ATOM   5194  C C   . ILE B 1 420 ? -49.915 -2.073  64.762 1.00 45.53  ? 622 ILE B C   1 
ATOM   5195  O O   . ILE B 1 420 ? -49.955 -2.805  65.767 1.00 46.35  ? 622 ILE B O   1 
ATOM   5196  C CB  . ILE B 1 420 ? -48.079 -0.432  65.260 1.00 44.90  ? 622 ILE B CB  1 
ATOM   5197  C CG1 . ILE B 1 420 ? -47.716 1.049   65.348 1.00 43.73  ? 622 ILE B CG1 1 
ATOM   5198  C CG2 . ILE B 1 420 ? -47.216 -1.117  64.221 1.00 44.89  ? 622 ILE B CG2 1 
ATOM   5199  C CD1 . ILE B 1 420 ? -46.359 1.299   65.947 1.00 42.52  ? 622 ILE B CD1 1 
ATOM   5200  N N   . PRO B 1 421 ? -50.203 -2.550  63.553 1.00 40.81  ? 623 PRO B N   1 
ATOM   5201  C CA  . PRO B 1 421 ? -50.530 -3.968  63.386 1.00 41.74  ? 623 PRO B CA  1 
ATOM   5202  C C   . PRO B 1 421 ? -49.377 -4.845  63.845 1.00 43.76  ? 623 PRO B C   1 
ATOM   5203  O O   . PRO B 1 421 ? -48.208 -4.462  63.768 1.00 44.41  ? 623 PRO B O   1 
ATOM   5204  C CB  . PRO B 1 421 ? -50.769 -4.100  61.878 1.00 40.34  ? 623 PRO B CB  1 
ATOM   5205  C CG  . PRO B 1 421 ? -51.170 -2.736  61.450 1.00 40.30  ? 623 PRO B CG  1 
ATOM   5206  C CD  . PRO B 1 421 ? -50.358 -1.802  62.296 1.00 39.81  ? 623 PRO B CD  1 
ATOM   5207  N N   . HIS B 1 422 ? -49.716 -6.035  64.324 1.00 42.96  ? 624 HIS B N   1 
ATOM   5208  C CA  . HIS B 1 422 ? -48.714 -6.969  64.819 1.00 44.40  ? 624 HIS B CA  1 
ATOM   5209  C C   . HIS B 1 422 ? -48.300 -7.849  63.650 1.00 43.07  ? 624 HIS B C   1 
ATOM   5210  O O   . HIS B 1 422 ? -49.068 -8.706  63.204 1.00 42.47  ? 624 HIS B O   1 
ATOM   5211  C CB  . HIS B 1 422 ? -49.271 -7.797  65.974 1.00 45.81  ? 624 HIS B CB  1 
ATOM   5212  C CG  . HIS B 1 422 ? -48.262 -8.697  66.614 1.00 50.88  ? 624 HIS B CG  1 
ATOM   5213  N ND1 . HIS B 1 422 ? -47.156 -8.218  67.279 1.00 53.79  ? 624 HIS B ND1 1 
ATOM   5214  C CD2 . HIS B 1 422 ? -48.188 -10.046 66.684 1.00 53.10  ? 624 HIS B CD2 1 
ATOM   5215  C CE1 . HIS B 1 422 ? -46.446 -9.233  67.736 1.00 55.34  ? 624 HIS B CE1 1 
ATOM   5216  N NE2 . HIS B 1 422 ? -47.050 -10.354 67.388 1.00 55.66  ? 624 HIS B NE2 1 
ATOM   5217  N N   . THR B 1 423 ? -47.081 -7.641  63.161 1.00 40.30  ? 625 THR B N   1 
ATOM   5218  C CA  . THR B 1 423 ? -46.626 -8.244  61.919 1.00 40.44  ? 625 THR B CA  1 
ATOM   5219  C C   . THR B 1 423 ? -45.130 -8.488  62.005 1.00 40.60  ? 625 THR B C   1 
ATOM   5220  O O   . THR B 1 423 ? -44.448 -7.978  62.897 1.00 40.35  ? 625 THR B O   1 
ATOM   5221  C CB  . THR B 1 423 ? -46.933 -7.366  60.695 1.00 39.46  ? 625 THR B CB  1 
ATOM   5222  O OG1 . THR B 1 423 ? -46.383 -6.057  60.891 1.00 38.97  ? 625 THR B OG1 1 
ATOM   5223  C CG2 . THR B 1 423 ? -48.431 -7.268  60.427 1.00 38.43  ? 625 THR B CG2 1 
ATOM   5224  N N   . ASP B 1 424 ? -44.631 -9.296  61.069 1.00 39.28  ? 626 ASP B N   1 
ATOM   5225  C CA  . ASP B 1 424 ? -43.192 -9.520  60.975 1.00 39.66  ? 626 ASP B CA  1 
ATOM   5226  C C   . ASP B 1 424 ? -42.439 -8.211  60.791 1.00 38.61  ? 626 ASP B C   1 
ATOM   5227  O O   . ASP B 1 424 ? -41.426 -7.971  61.458 1.00 39.55  ? 626 ASP B O   1 
ATOM   5228  C CB  . ASP B 1 424 ? -42.883 -10.477 59.828 1.00 39.79  ? 626 ASP B CB  1 
ATOM   5229  C CG  . ASP B 1 424 ? -43.280 -11.894 60.139 1.00 43.70  ? 626 ASP B CG  1 
ATOM   5230  O OD1 . ASP B 1 424 ? -43.475 -12.191 61.332 1.00 47.53  ? 626 ASP B OD1 1 
ATOM   5231  O OD2 . ASP B 1 424 ? -43.398 -12.707 59.200 1.00 45.86  ? 626 ASP B OD2 1 
ATOM   5232  N N   . GLY B 1 425 ? -42.917 -7.349  59.901 1.00 37.23  ? 627 GLY B N   1 
ATOM   5233  C CA  . GLY B 1 425 ? -42.224 -6.105  59.638 1.00 34.73  ? 627 GLY B CA  1 
ATOM   5234  C C   . GLY B 1 425 ? -43.156 -5.016  59.161 1.00 34.05  ? 627 GLY B C   1 
ATOM   5235  O O   . GLY B 1 425 ? -44.243 -5.273  58.634 1.00 34.16  ? 627 GLY B O   1 
ATOM   5236  N N   . ASN B 1 426 ? -42.706 -3.782  59.359 1.00 34.63  ? 628 ASN B N   1 
ATOM   5237  C CA  . ASN B 1 426 ? -43.392 -2.599  58.868 1.00 34.25  ? 628 ASN B CA  1 
ATOM   5238  C C   . ASN B 1 426 ? -42.353 -1.516  58.644 1.00 33.66  ? 628 ASN B C   1 
ATOM   5239  O O   . ASN B 1 426 ? -41.228 -1.599  59.142 1.00 33.00  ? 628 ASN B O   1 
ATOM   5240  C CB  . ASN B 1 426 ? -44.497 -2.134  59.832 1.00 34.65  ? 628 ASN B CB  1 
ATOM   5241  C CG  . ASN B 1 426 ? -43.977 -1.787  61.222 1.00 34.05  ? 628 ASN B CG  1 
ATOM   5242  O OD1 . ASN B 1 426 ? -42.884 -1.254  61.388 1.00 32.38  ? 628 ASN B OD1 1 
ATOM   5243  N ND2 . ASN B 1 426 ? -44.772 -2.100  62.232 1.00 34.96  ? 628 ASN B ND2 1 
ATOM   5244  N N   . PHE B 1 427 ? -42.731 -0.498  57.880 1.00 32.57  ? 629 PHE B N   1 
ATOM   5245  C CA  . PHE B 1 427 ? -41.854 0.637   57.646 1.00 32.16  ? 629 PHE B CA  1 
ATOM   5246  C C   . PHE B 1 427 ? -42.588 1.920   57.981 1.00 33.66  ? 629 PHE B C   1 
ATOM   5247  O O   . PHE B 1 427 ? -43.688 2.160   57.476 1.00 33.64  ? 629 PHE B O   1 
ATOM   5248  C CB  . PHE B 1 427 ? -41.359 0.686   56.205 1.00 27.56  ? 629 PHE B CB  1 
ATOM   5249  C CG  . PHE B 1 427 ? -40.503 1.877   55.914 1.00 27.99  ? 629 PHE B CG  1 
ATOM   5250  C CD1 . PHE B 1 427 ? -39.181 1.902   56.314 1.00 26.37  ? 629 PHE B CD1 1 
ATOM   5251  C CD2 . PHE B 1 427 ? -41.017 2.973   55.253 1.00 27.68  ? 629 PHE B CD2 1 
ATOM   5252  C CE1 . PHE B 1 427 ? -38.387 2.994   56.056 1.00 26.29  ? 629 PHE B CE1 1 
ATOM   5253  C CE2 . PHE B 1 427 ? -40.227 4.066   54.993 1.00 27.77  ? 629 PHE B CE2 1 
ATOM   5254  C CZ  . PHE B 1 427 ? -38.910 4.076   55.395 1.00 27.21  ? 629 PHE B CZ  1 
ATOM   5255  N N   . HIS B 1 428 ? -41.961 2.744   58.815 1.00 34.05  ? 630 HIS B N   1 
ATOM   5256  C CA  . HIS B 1 428 ? -42.489 4.023   59.262 1.00 35.16  ? 630 HIS B CA  1 
ATOM   5257  C C   . HIS B 1 428 ? -43.900 3.794   59.793 1.00 35.69  ? 630 HIS B C   1 
ATOM   5258  O O   . HIS B 1 428 ? -44.885 4.165   59.143 1.00 36.29  ? 630 HIS B O   1 
ATOM   5259  C CB  . HIS B 1 428 ? -42.466 5.048   58.127 1.00 33.57  ? 630 HIS B CB  1 
ATOM   5260  C CG  . HIS B 1 428 ? -42.630 6.462   58.588 1.00 35.01  ? 630 HIS B CG  1 
ATOM   5261  N ND1 . HIS B 1 428 ? -41.695 7.093   59.378 1.00 35.60  ? 630 HIS B ND1 1 
ATOM   5262  C CD2 . HIS B 1 428 ? -43.618 7.364   58.379 1.00 35.27  ? 630 HIS B CD2 1 
ATOM   5263  C CE1 . HIS B 1 428 ? -42.096 8.326   59.631 1.00 36.09  ? 630 HIS B CE1 1 
ATOM   5264  N NE2 . HIS B 1 428 ? -43.260 8.515   59.038 1.00 35.89  ? 630 HIS B NE2 1 
ATOM   5265  N N   . PRO B 1 429 ? -44.026 3.176   60.966 1.00 39.22  ? 631 PRO B N   1 
ATOM   5266  C CA  . PRO B 1 429 ? -45.333 2.714   61.456 1.00 38.84  ? 631 PRO B CA  1 
ATOM   5267  C C   . PRO B 1 429 ? -46.376 3.804   61.651 1.00 38.82  ? 631 PRO B C   1 
ATOM   5268  O O   . PRO B 1 429 ? -47.530 3.488   61.950 1.00 40.15  ? 631 PRO B O   1 
ATOM   5269  C CB  . PRO B 1 429 ? -44.979 2.041   62.786 1.00 40.56  ? 631 PRO B CB  1 
ATOM   5270  C CG  . PRO B 1 429 ? -43.731 2.712   63.220 1.00 39.99  ? 631 PRO B CG  1 
ATOM   5271  C CD  . PRO B 1 429 ? -42.963 2.963   61.961 1.00 40.05  ? 631 PRO B CD  1 
ATOM   5272  N N   . SER B 1 430 ? -45.978 5.069   61.558 1.00 41.32  ? 632 SER B N   1 
ATOM   5273  C CA  . SER B 1 430 ? -46.899 6.179   61.759 1.00 40.70  ? 632 SER B CA  1 
ATOM   5274  C C   . SER B 1 430 ? -48.185 5.962   60.958 1.00 40.00  ? 632 SER B C   1 
ATOM   5275  O O   . SER B 1 430 ? -48.119 5.645   59.762 1.00 40.06  ? 632 SER B O   1 
ATOM   5276  C CB  . SER B 1 430 ? -46.237 7.489   61.334 1.00 35.97  ? 632 SER B CB  1 
ATOM   5277  O OG  . SER B 1 430 ? -47.141 8.571   61.447 1.00 40.32  ? 632 SER B OG  1 
ATOM   5278  N N   . PRO B 1 431 ? -49.356 6.111   61.574 1.00 40.02  ? 633 PRO B N   1 
ATOM   5279  C CA  . PRO B 1 431 ? -50.603 5.813   60.867 1.00 39.73  ? 633 PRO B CA  1 
ATOM   5280  C C   . PRO B 1 431 ? -50.927 6.864   59.821 1.00 39.79  ? 633 PRO B C   1 
ATOM   5281  O O   . PRO B 1 431 ? -50.622 8.049   59.975 1.00 40.21  ? 633 PRO B O   1 
ATOM   5282  C CB  . PRO B 1 431 ? -51.648 5.804   61.986 1.00 38.93  ? 633 PRO B CB  1 
ATOM   5283  C CG  . PRO B 1 431 ? -51.090 6.709   63.014 1.00 40.10  ? 633 PRO B CG  1 
ATOM   5284  C CD  . PRO B 1 431 ? -49.598 6.534   62.963 1.00 39.17  ? 633 PRO B CD  1 
ATOM   5285  N N   . LEU B 1 432 ? -51.574 6.413   58.749 1.00 40.84  ? 634 LEU B N   1 
ATOM   5286  C CA  . LEU B 1 432 ? -51.780 7.262   57.585 1.00 40.84  ? 634 LEU B CA  1 
ATOM   5287  C C   . LEU B 1 432 ? -52.861 8.315   57.787 1.00 42.11  ? 634 LEU B C   1 
ATOM   5288  O O   . LEU B 1 432 ? -52.827 9.345   57.108 1.00 42.14  ? 634 LEU B O   1 
ATOM   5289  C CB  . LEU B 1 432 ? -52.108 6.401   56.369 1.00 41.47  ? 634 LEU B CB  1 
ATOM   5290  C CG  . LEU B 1 432 ? -50.958 5.495   55.935 1.00 39.54  ? 634 LEU B CG  1 
ATOM   5291  C CD1 . LEU B 1 432 ? -51.387 4.589   54.801 1.00 38.73  ? 634 LEU B CD1 1 
ATOM   5292  C CD2 . LEU B 1 432 ? -49.758 6.331   55.533 1.00 36.77  ? 634 LEU B CD2 1 
ATOM   5293  N N   . MET B 1 433 ? -53.809 8.101   58.697 1.00 43.23  ? 635 MET B N   1 
ATOM   5294  C CA  . MET B 1 433 ? -54.808 9.131   58.956 1.00 44.02  ? 635 MET B CA  1 
ATOM   5295  C C   . MET B 1 433 ? -54.310 10.209  59.905 1.00 44.18  ? 635 MET B C   1 
ATOM   5296  O O   . MET B 1 433 ? -55.058 11.147  60.198 1.00 43.69  ? 635 MET B O   1 
ATOM   5297  C CB  . MET B 1 433 ? -56.097 8.520   59.511 1.00 40.76  ? 635 MET B CB  1 
ATOM   5298  C CG  . MET B 1 433 ? -56.863 7.667   58.516 1.00 43.16  ? 635 MET B CG  1 
ATOM   5299  S SD  . MET B 1 433 ? -58.480 7.157   59.123 1.00 48.88  ? 635 MET B SD  1 
ATOM   5300  C CE  . MET B 1 433 ? -58.057 5.878   60.296 1.00 47.96  ? 635 MET B CE  1 
ATOM   5301  N N   . GLY B 1 434 ? -53.080 10.106  60.377 1.00 44.94  ? 636 GLY B N   1 
ATOM   5302  C CA  . GLY B 1 434 ? -52.501 11.094  61.258 1.00 43.99  ? 636 GLY B CA  1 
ATOM   5303  C C   . GLY B 1 434 ? -52.464 10.616  62.701 1.00 43.77  ? 636 GLY B C   1 
ATOM   5304  O O   . GLY B 1 434 ? -53.292 9.821   63.153 1.00 45.01  ? 636 GLY B O   1 
ATOM   5305  N N   . GLY B 1 435 ? -51.484 11.126  63.430 1.00 47.83  ? 637 GLY B N   1 
ATOM   5306  C CA  . GLY B 1 435 ? -51.294 10.764  64.815 1.00 46.04  ? 637 GLY B CA  1 
ATOM   5307  C C   . GLY B 1 435 ? -50.119 9.836   65.044 1.00 44.60  ? 637 GLY B C   1 
ATOM   5308  O O   . GLY B 1 435 ? -49.310 9.556   64.157 1.00 44.21  ? 637 GLY B O   1 
ATOM   5309  N N   . PHE B 1 436 ? -50.040 9.345   66.276 1.00 45.07  ? 638 PHE B N   1 
ATOM   5310  C CA  . PHE B 1 436 ? -48.893 8.593   66.768 1.00 44.85  ? 638 PHE B CA  1 
ATOM   5311  C C   . PHE B 1 436 ? -49.154 7.105   66.595 1.00 46.52  ? 638 PHE B C   1 
ATOM   5312  O O   . PHE B 1 436 ? -50.239 6.621   66.934 1.00 48.45  ? 638 PHE B O   1 
ATOM   5313  C CB  . PHE B 1 436 ? -48.632 8.905   68.240 1.00 47.25  ? 638 PHE B CB  1 
ATOM   5314  C CG  . PHE B 1 436 ? -48.383 10.357  68.520 1.00 46.69  ? 638 PHE B CG  1 
ATOM   5315  C CD1 . PHE B 1 436 ? -47.129 10.908  68.339 1.00 46.07  ? 638 PHE B CD1 1 
ATOM   5316  C CD2 . PHE B 1 436 ? -49.404 11.166  68.984 1.00 46.35  ? 638 PHE B CD2 1 
ATOM   5317  C CE1 . PHE B 1 436 ? -46.903 12.240  68.605 1.00 46.48  ? 638 PHE B CE1 1 
ATOM   5318  C CE2 . PHE B 1 436 ? -49.183 12.497  69.252 1.00 46.61  ? 638 PHE B CE2 1 
ATOM   5319  C CZ  . PHE B 1 436 ? -47.932 13.035  69.063 1.00 46.20  ? 638 PHE B CZ  1 
ATOM   5320  N N   . GLY B 1 437 ? -48.169 6.384   66.066 1.00 45.94  ? 639 GLY B N   1 
ATOM   5321  C CA  . GLY B 1 437 ? -48.237 4.934   66.069 1.00 46.33  ? 639 GLY B CA  1 
ATOM   5322  C C   . GLY B 1 437 ? -47.732 4.375   67.388 1.00 47.41  ? 639 GLY B C   1 
ATOM   5323  O O   . GLY B 1 437 ? -46.780 4.881   67.980 1.00 47.44  ? 639 GLY B O   1 
ATOM   5324  N N   . MET B 1 438 ? -48.384 3.311   67.848 1.00 47.13  ? 640 MET B N   1 
ATOM   5325  C CA  . MET B 1 438 ? -48.005 2.643   69.086 1.00 47.74  ? 640 MET B CA  1 
ATOM   5326  C C   . MET B 1 438 ? -48.243 1.150   68.938 1.00 48.45  ? 640 MET B C   1 
ATOM   5327  O O   . MET B 1 438 ? -49.283 0.738   68.419 1.00 48.48  ? 640 MET B O   1 
ATOM   5328  C CB  . MET B 1 438 ? -48.801 3.186   70.280 1.00 50.02  ? 640 MET B CB  1 
ATOM   5329  C CG  . MET B 1 438 ? -48.484 4.627   70.645 1.00 54.53  ? 640 MET B CG  1 
ATOM   5330  S SD  . MET B 1 438 ? -49.473 5.239   72.014 1.00 59.00  ? 640 MET B SD  1 
ATOM   5331  C CE  . MET B 1 438 ? -48.768 4.300   73.363 1.00 58.89  ? 640 MET B CE  1 
ATOM   5332  N N   . LYS B 1 439 ? -47.284 0.341   69.394 1.00 49.82  ? 641 LYS B N   1 
ATOM   5333  C CA  . LYS B 1 439 ? -47.509 -1.100  69.409 1.00 51.76  ? 641 LYS B CA  1 
ATOM   5334  C C   . LYS B 1 439 ? -48.416 -1.508  70.559 1.00 51.71  ? 641 LYS B C   1 
ATOM   5335  O O   . LYS B 1 439 ? -49.205 -2.448  70.422 1.00 52.43  ? 641 LYS B O   1 
ATOM   5336  C CB  . LYS B 1 439 ? -46.186 -1.858  69.494 1.00 47.78  ? 641 LYS B CB  1 
ATOM   5337  C CG  . LYS B 1 439 ? -45.352 -1.802  68.232 1.00 53.68  ? 641 LYS B CG  1 
ATOM   5338  C CD  . LYS B 1 439 ? -44.220 -2.814  68.285 1.00 60.10  ? 641 LYS B CD  1 
ATOM   5339  C CE  . LYS B 1 439 ? -43.232 -2.492  69.391 1.00 62.47  ? 641 LYS B CE  1 
ATOM   5340  N NZ  . LYS B 1 439 ? -42.074 -3.425  69.377 1.00 63.22  ? 641 LYS B NZ  1 
ATOM   5341  N N   . HIS B 1 440 ? -48.320 -0.819  71.697 1.00 53.77  ? 642 HIS B N   1 
ATOM   5342  C CA  . HIS B 1 440 ? -49.165 -1.069  72.861 1.00 53.61  ? 642 HIS B CA  1 
ATOM   5343  C C   . HIS B 1 440 ? -49.910 0.221   73.183 1.00 51.96  ? 642 HIS B C   1 
ATOM   5344  O O   . HIS B 1 440 ? -49.547 0.942   74.124 1.00 52.07  ? 642 HIS B O   1 
ATOM   5345  C CB  . HIS B 1 440 ? -48.344 -1.548  74.055 1.00 51.17  ? 642 HIS B CB  1 
ATOM   5346  C CG  . HIS B 1 440 ? -47.560 -2.793  73.785 1.00 56.28  ? 642 HIS B CG  1 
ATOM   5347  N ND1 . HIS B 1 440 ? -48.155 -4.020  73.587 1.00 57.54  ? 642 HIS B ND1 1 
ATOM   5348  C CD2 . HIS B 1 440 ? -46.227 -3.001  73.682 1.00 57.37  ? 642 HIS B CD2 1 
ATOM   5349  C CE1 . HIS B 1 440 ? -47.223 -4.930  73.369 1.00 58.73  ? 642 HIS B CE1 1 
ATOM   5350  N NE2 . HIS B 1 440 ? -46.044 -4.338  73.423 1.00 59.95  ? 642 HIS B NE2 1 
ATOM   5351  N N   . PRO B 1 441 ? -50.951 0.546   72.424 1.00 54.88  ? 643 PRO B N   1 
ATOM   5352  C CA  . PRO B 1 441 ? -51.699 1.773   72.676 1.00 53.29  ? 643 PRO B CA  1 
ATOM   5353  C C   . PRO B 1 441 ? -52.615 1.599   73.873 1.00 52.55  ? 643 PRO B C   1 
ATOM   5354  O O   . PRO B 1 441 ? -52.651 0.517   74.479 1.00 52.63  ? 643 PRO B O   1 
ATOM   5355  C CB  . PRO B 1 441 ? -52.500 1.957   71.379 1.00 51.86  ? 643 PRO B CB  1 
ATOM   5356  C CG  . PRO B 1 441 ? -52.727 0.579   70.912 1.00 51.68  ? 643 PRO B CG  1 
ATOM   5357  C CD  . PRO B 1 441 ? -51.508 -0.213  71.291 1.00 51.64  ? 643 PRO B CD  1 
ATOM   5358  N N   . PRO B 1 442 ? -53.363 2.645   74.262 1.00 52.09  ? 644 PRO B N   1 
ATOM   5359  C CA  . PRO B 1 442 ? -54.406 2.497   75.282 1.00 51.58  ? 644 PRO B CA  1 
ATOM   5360  C C   . PRO B 1 442 ? -55.422 1.405   74.954 1.00 51.87  ? 644 PRO B C   1 
ATOM   5361  O O   . PRO B 1 442 ? -55.679 1.155   73.779 1.00 51.60  ? 644 PRO B O   1 
ATOM   5362  C CB  . PRO B 1 442 ? -55.076 3.868   75.286 1.00 51.49  ? 644 PRO B CB  1 
ATOM   5363  C CG  . PRO B 1 442 ? -54.005 4.797   74.896 1.00 51.84  ? 644 PRO B CG  1 
ATOM   5364  C CD  . PRO B 1 442 ? -53.136 4.061   73.921 1.00 51.57  ? 644 PRO B CD  1 
ATOM   5365  N N   . ASP C 1 17  ? -3.640  40.013  72.298 1.00 65.45  ? 219 ASP C N   1 
ATOM   5366  C CA  . ASP C 1 17  ? -2.746  40.068  73.447 1.00 65.70  ? 219 ASP C CA  1 
ATOM   5367  C C   . ASP C 1 17  ? -1.711  41.173  73.260 1.00 63.41  ? 219 ASP C C   1 
ATOM   5368  O O   . ASP C 1 17  ? -1.486  41.986  74.156 1.00 63.45  ? 219 ASP C O   1 
ATOM   5369  C CB  . ASP C 1 17  ? -2.058  38.718  73.657 1.00 63.12  ? 219 ASP C CB  1 
ATOM   5370  C CG  . ASP C 1 17  ? -1.176  38.697  74.887 1.00 66.79  ? 219 ASP C CG  1 
ATOM   5371  O OD1 . ASP C 1 17  ? -1.718  38.788  76.008 1.00 68.57  ? 219 ASP C OD1 1 
ATOM   5372  O OD2 . ASP C 1 17  ? 0.059   38.584  74.734 1.00 67.89  ? 219 ASP C OD2 1 
ATOM   5373  N N   . GLY C 1 18  ? -1.090  41.200  72.084 1.00 67.95  ? 220 GLY C N   1 
ATOM   5374  C CA  . GLY C 1 18  ? -0.126  42.234  71.759 1.00 62.57  ? 220 GLY C CA  1 
ATOM   5375  C C   . GLY C 1 18  ? -0.064  42.441  70.262 1.00 59.22  ? 220 GLY C C   1 
ATOM   5376  O O   . GLY C 1 18  ? -0.418  41.557  69.475 1.00 59.95  ? 220 GLY C O   1 
ATOM   5377  N N   . VAL C 1 19  ? 0.395   43.631  69.873 1.00 60.67  ? 221 VAL C N   1 
ATOM   5378  C CA  . VAL C 1 19  ? 0.463   43.967  68.455 1.00 56.44  ? 221 VAL C CA  1 
ATOM   5379  C C   . VAL C 1 19  ? 1.570   43.176  67.770 1.00 55.31  ? 221 VAL C C   1 
ATOM   5380  O O   . VAL C 1 19  ? 1.399   42.682  66.650 1.00 56.17  ? 221 VAL C O   1 
ATOM   5381  C CB  . VAL C 1 19  ? 0.654   45.484  68.277 1.00 53.99  ? 221 VAL C CB  1 
ATOM   5382  C CG1 . VAL C 1 19  ? 0.820   45.836  66.807 1.00 53.24  ? 221 VAL C CG1 1 
ATOM   5383  C CG2 . VAL C 1 19  ? -0.522  46.237  68.874 1.00 54.02  ? 221 VAL C CG2 1 
ATOM   5384  N N   . GLY C 1 20  ? 2.714   43.038  68.430 1.00 58.89  ? 222 GLY C N   1 
ATOM   5385  C CA  . GLY C 1 20  ? 3.861   42.342  67.893 1.00 56.38  ? 222 GLY C CA  1 
ATOM   5386  C C   . GLY C 1 20  ? 4.059   40.935  68.405 1.00 56.11  ? 222 GLY C C   1 
ATOM   5387  O O   . GLY C 1 20  ? 5.183   40.428  68.363 1.00 56.34  ? 222 GLY C O   1 
ATOM   5388  N N   . SER C 1 21  ? 3.010   40.293  68.904 1.00 56.24  ? 223 SER C N   1 
ATOM   5389  C CA  . SER C 1 21  ? 3.075   38.915  69.360 1.00 54.80  ? 223 SER C CA  1 
ATOM   5390  C C   . SER C 1 21  ? 2.103   38.072  68.547 1.00 53.52  ? 223 SER C C   1 
ATOM   5391  O O   . SER C 1 21  ? 0.899   38.343  68.530 1.00 55.21  ? 223 SER C O   1 
ATOM   5392  C CB  . SER C 1 21  ? 2.750   38.808  70.851 1.00 55.45  ? 223 SER C CB  1 
ATOM   5393  O OG  . SER C 1 21  ? 2.793   37.461  71.285 1.00 60.49  ? 223 SER C OG  1 
ATOM   5394  N N   . SER C 1 22  ? 2.634   37.062  67.865 1.00 53.23  ? 224 SER C N   1 
ATOM   5395  C CA  . SER C 1 22  ? 1.817   36.190  67.037 1.00 51.51  ? 224 SER C CA  1 
ATOM   5396  C C   . SER C 1 22  ? 0.819   35.424  67.894 1.00 49.93  ? 224 SER C C   1 
ATOM   5397  O O   . SER C 1 22  ? 1.120   35.032  69.024 1.00 48.63  ? 224 SER C O   1 
ATOM   5398  C CB  . SER C 1 22  ? 2.698   35.216  66.255 1.00 46.42  ? 224 SER C CB  1 
ATOM   5399  O OG  . SER C 1 22  ? 1.917   34.325  65.480 1.00 50.57  ? 224 SER C OG  1 
ATOM   5400  N N   . SER C 1 23  ? -0.379  35.225  67.352 1.00 44.44  ? 225 SER C N   1 
ATOM   5401  C CA  . SER C 1 23  ? -1.467  34.578  68.071 1.00 43.78  ? 225 SER C CA  1 
ATOM   5402  C C   . SER C 1 23  ? -1.584  33.089  67.777 1.00 43.56  ? 225 SER C C   1 
ATOM   5403  O O   . SER C 1 23  ? -2.505  32.445  68.285 1.00 44.67  ? 225 SER C O   1 
ATOM   5404  C CB  . SER C 1 23  ? -2.790  35.277  67.754 1.00 45.87  ? 225 SER C CB  1 
ATOM   5405  O OG  . SER C 1 23  ? -3.093  35.188  66.375 1.00 47.78  ? 225 SER C OG  1 
ATOM   5406  N N   . GLY C 1 24  ? -0.686  32.529  66.977 1.00 41.31  ? 226 GLY C N   1 
ATOM   5407  C CA  . GLY C 1 24  ? -0.733  31.104  66.702 1.00 40.98  ? 226 GLY C CA  1 
ATOM   5408  C C   . GLY C 1 24  ? 0.377   30.711  65.757 1.00 41.05  ? 226 GLY C C   1 
ATOM   5409  O O   . GLY C 1 24  ? 0.959   31.548  65.062 1.00 41.68  ? 226 GLY C O   1 
ATOM   5410  N N   . ASN C 1 25  ? 0.663   29.413  65.742 1.00 35.78  ? 227 ASN C N   1 
ATOM   5411  C CA  . ASN C 1 25  ? 1.718   28.850  64.914 1.00 36.11  ? 227 ASN C CA  1 
ATOM   5412  C C   . ASN C 1 25  ? 1.124   28.138  63.706 1.00 37.76  ? 227 ASN C C   1 
ATOM   5413  O O   . ASN C 1 25  ? -0.094  28.020  63.553 1.00 40.21  ? 227 ASN C O   1 
ATOM   5414  C CB  . ASN C 1 25  ? 2.588   27.879  65.718 1.00 39.59  ? 227 ASN C CB  1 
ATOM   5415  C CG  . ASN C 1 25  ? 3.438   28.579  66.752 1.00 40.31  ? 227 ASN C CG  1 
ATOM   5416  O OD1 . ASN C 1 25  ? 3.738   29.763  66.625 1.00 40.99  ? 227 ASN C OD1 1 
ATOM   5417  N ND2 . ASN C 1 25  ? 3.833   27.849  67.785 1.00 40.74  ? 227 ASN C ND2 1 
ATOM   5418  N N   . TRP C 1 26  ? 2.018   27.644  62.854 1.00 32.35  ? 228 TRP C N   1 
ATOM   5419  C CA  . TRP C 1 26  ? 1.647   26.940  61.634 1.00 32.87  ? 228 TRP C CA  1 
ATOM   5420  C C   . TRP C 1 26  ? 1.662   25.442  61.906 1.00 34.36  ? 228 TRP C C   1 
ATOM   5421  O O   . TRP C 1 26  ? 2.712   24.879  62.228 1.00 34.78  ? 228 TRP C O   1 
ATOM   5422  C CB  . TRP C 1 26  ? 2.620   27.269  60.503 1.00 32.54  ? 228 TRP C CB  1 
ATOM   5423  C CG  . TRP C 1 26  ? 2.286   26.603  59.203 1.00 31.82  ? 228 TRP C CG  1 
ATOM   5424  C CD1 . TRP C 1 26  ? 2.706   25.377  58.784 1.00 31.22  ? 228 TRP C CD1 1 
ATOM   5425  C CD2 . TRP C 1 26  ? 1.540   27.160  58.119 1.00 31.28  ? 228 TRP C CD2 1 
ATOM   5426  N NE1 . TRP C 1 26  ? 2.225   25.113  57.528 1.00 31.60  ? 228 TRP C NE1 1 
ATOM   5427  C CE2 . TRP C 1 26  ? 1.511   26.197  57.095 1.00 31.75  ? 228 TRP C CE2 1 
ATOM   5428  C CE3 . TRP C 1 26  ? 0.881   28.375  57.919 1.00 31.08  ? 228 TRP C CE3 1 
ATOM   5429  C CZ2 . TRP C 1 26  ? 0.846   26.408  55.893 1.00 32.13  ? 228 TRP C CZ2 1 
ATOM   5430  C CZ3 . TRP C 1 26  ? 0.222   28.584  56.723 1.00 31.88  ? 228 TRP C CZ3 1 
ATOM   5431  C CH2 . TRP C 1 26  ? 0.208   27.604  55.727 1.00 32.09  ? 228 TRP C CH2 1 
ATOM   5432  N N   . HIS C 1 27  ? 0.508   24.795  61.771 1.00 31.47  ? 229 HIS C N   1 
ATOM   5433  C CA  . HIS C 1 27  ? 0.407   23.346  61.913 1.00 34.46  ? 229 HIS C CA  1 
ATOM   5434  C C   . HIS C 1 27  ? -0.128  22.748  60.619 1.00 36.08  ? 229 HIS C C   1 
ATOM   5435  O O   . HIS C 1 27  ? -1.291  22.962  60.264 1.00 37.18  ? 229 HIS C O   1 
ATOM   5436  C CB  . HIS C 1 27  ? -0.485  22.963  63.093 1.00 38.01  ? 229 HIS C CB  1 
ATOM   5437  C CG  . HIS C 1 27  ? 0.101   23.281  64.431 1.00 42.17  ? 229 HIS C CG  1 
ATOM   5438  N ND1 . HIS C 1 27  ? -0.023  24.517  65.026 1.00 43.01  ? 229 HIS C ND1 1 
ATOM   5439  C CD2 . HIS C 1 27  ? 0.816   22.519  65.291 1.00 43.85  ? 229 HIS C CD2 1 
ATOM   5440  C CE1 . HIS C 1 27  ? 0.591   24.504  66.196 1.00 44.51  ? 229 HIS C CE1 1 
ATOM   5441  N NE2 . HIS C 1 27  ? 1.108   23.303  66.380 1.00 45.97  ? 229 HIS C NE2 1 
ATOM   5442  N N   . CYS C 1 28  ? 0.725   22.012  59.914 1.00 31.45  ? 230 CYS C N   1 
ATOM   5443  C CA  . CYS C 1 28  ? 0.304   21.117  58.843 1.00 34.24  ? 230 CYS C CA  1 
ATOM   5444  C C   . CYS C 1 28  ? 1.116   19.840  58.951 1.00 35.66  ? 230 CYS C C   1 
ATOM   5445  O O   . CYS C 1 28  ? 2.347   19.893  58.956 1.00 37.05  ? 230 CYS C O   1 
ATOM   5446  C CB  . CYS C 1 28  ? 0.487   21.739  57.455 1.00 38.66  ? 230 CYS C CB  1 
ATOM   5447  S SG  . CYS C 1 28  ? -0.658  23.060  57.034 1.00 41.71  ? 230 CYS C SG  1 
ATOM   5448  N N   . ASP C 1 29  ? 0.422   18.707  59.049 1.00 33.74  ? 231 ASP C N   1 
ATOM   5449  C CA  . ASP C 1 29  ? 1.011   17.376  58.961 1.00 35.94  ? 231 ASP C CA  1 
ATOM   5450  C C   . ASP C 1 29  ? -0.081  16.337  59.156 1.00 33.84  ? 231 ASP C C   1 
ATOM   5451  O O   . ASP C 1 29  ? -1.235  16.683  59.426 1.00 34.19  ? 231 ASP C O   1 
ATOM   5452  C CB  . ASP C 1 29  ? 2.130   17.164  59.987 1.00 32.14  ? 231 ASP C CB  1 
ATOM   5453  C CG  . ASP C 1 29  ? 1.661   17.324  61.413 1.00 36.27  ? 231 ASP C CG  1 
ATOM   5454  O OD1 . ASP C 1 29  ? 0.508   17.748  61.625 1.00 38.56  ? 231 ASP C OD1 1 
ATOM   5455  O OD2 . ASP C 1 29  ? 2.448   17.014  62.330 1.00 38.54  ? 231 ASP C OD2 1 
ATOM   5456  N N   . SER C 1 30  ? 0.285   15.074  59.023 1.00 31.93  ? 232 SER C N   1 
ATOM   5457  C CA  . SER C 1 30  ? -0.658  13.996  59.208 1.00 31.09  ? 232 SER C CA  1 
ATOM   5458  C C   . SER C 1 30  ? 0.081   12.881  59.901 1.00 30.61  ? 232 SER C C   1 
ATOM   5459  O O   . SER C 1 30  ? 0.829   12.139  59.274 1.00 30.91  ? 232 SER C O   1 
ATOM   5460  C CB  . SER C 1 30  ? -1.197  13.511  57.869 1.00 28.14  ? 232 SER C CB  1 
ATOM   5461  O OG  . SER C 1 30  ? -0.226  12.747  57.181 1.00 28.19  ? 232 SER C OG  1 
ATOM   5462  N N   . GLN C 1 31  ? -0.123  12.765  61.203 1.00 31.42  ? 233 GLN C N   1 
ATOM   5463  C CA  . GLN C 1 31  ? 0.539   11.726  61.957 1.00 31.07  ? 233 GLN C CA  1 
ATOM   5464  C C   . GLN C 1 31  ? -0.421  10.572  62.092 1.00 29.34  ? 233 GLN C C   1 
ATOM   5465  O O   . GLN C 1 31  ? -1.556  10.755  62.504 1.00 29.11  ? 233 GLN C O   1 
ATOM   5466  C CB  . GLN C 1 31  ? 0.944   12.243  63.332 1.00 30.24  ? 233 GLN C CB  1 
ATOM   5467  C CG  . GLN C 1 31  ? -0.203  12.348  64.314 1.00 37.74  ? 233 GLN C CG  1 
ATOM   5468  C CD  . GLN C 1 31  ? 0.148   13.205  65.510 1.00 41.85  ? 233 GLN C CD  1 
ATOM   5469  O OE1 . GLN C 1 31  ? 0.031   12.773  66.657 1.00 43.61  ? 233 GLN C OE1 1 
ATOM   5470  N NE2 . GLN C 1 31  ? 0.591   14.427  65.248 1.00 43.12  ? 233 GLN C NE2 1 
ATOM   5471  N N   . TRP C 1 32  ? 0.035   9.380   61.730 1.00 31.66  ? 234 TRP C N   1 
ATOM   5472  C CA  . TRP C 1 32  ? -0.804  8.202   61.804 1.00 31.22  ? 234 TRP C CA  1 
ATOM   5473  C C   . TRP C 1 32  ? -0.380  7.347   62.970 1.00 32.78  ? 234 TRP C C   1 
ATOM   5474  O O   . TRP C 1 32  ? 0.730   6.839   62.989 1.00 32.97  ? 234 TRP C O   1 
ATOM   5475  C CB  . TRP C 1 32  ? -0.627  7.371   60.540 1.00 26.90  ? 234 TRP C CB  1 
ATOM   5476  C CG  . TRP C 1 32  ? -1.005  8.060   59.285 1.00 25.13  ? 234 TRP C CG  1 
ATOM   5477  C CD1 . TRP C 1 32  ? -0.410  9.151   58.737 1.00 24.54  ? 234 TRP C CD1 1 
ATOM   5478  C CD2 . TRP C 1 32  ? -2.054  7.686   58.396 1.00 23.70  ? 234 TRP C CD2 1 
ATOM   5479  N NE1 . TRP C 1 32  ? -1.031  9.489   57.566 1.00 22.19  ? 234 TRP C NE1 1 
ATOM   5480  C CE2 . TRP C 1 32  ? -2.048  8.603   57.336 1.00 22.63  ? 234 TRP C CE2 1 
ATOM   5481  C CE3 . TRP C 1 32  ? -3.006  6.667   58.398 1.00 21.77  ? 234 TRP C CE3 1 
ATOM   5482  C CZ2 . TRP C 1 32  ? -2.954  8.533   56.290 1.00 21.84  ? 234 TRP C CZ2 1 
ATOM   5483  C CZ3 . TRP C 1 32  ? -3.899  6.600   57.358 1.00 21.72  ? 234 TRP C CZ3 1 
ATOM   5484  C CH2 . TRP C 1 32  ? -3.870  7.526   56.321 1.00 22.12  ? 234 TRP C CH2 1 
ATOM   5485  N N   . LEU C 1 33  ? -1.261  7.176   63.943 1.00 37.21  ? 235 LEU C N   1 
ATOM   5486  C CA  . LEU C 1 33  ? -0.945  6.338   65.085 1.00 39.28  ? 235 LEU C CA  1 
ATOM   5487  C C   . LEU C 1 33  ? -2.057  5.339   65.334 1.00 40.28  ? 235 LEU C C   1 
ATOM   5488  O O   . LEU C 1 33  ? -3.195  5.721   65.543 1.00 41.32  ? 235 LEU C O   1 
ATOM   5489  C CB  . LEU C 1 33  ? -0.701  7.192   66.327 1.00 41.36  ? 235 LEU C CB  1 
ATOM   5490  C CG  . LEU C 1 33  ? -1.441  8.527   66.397 1.00 43.36  ? 235 LEU C CG  1 
ATOM   5491  C CD1 . LEU C 1 33  ? -2.931  8.336   66.182 1.00 43.22  ? 235 LEU C CD1 1 
ATOM   5492  C CD2 . LEU C 1 33  ? -1.173  9.209   67.727 1.00 43.75  ? 235 LEU C CD2 1 
ATOM   5493  N N   . GLY C 1 34  ? -1.719  4.059   65.365 1.00 37.13  ? 236 GLY C N   1 
ATOM   5494  C CA  . GLY C 1 34  ? -2.713  3.030   65.595 1.00 37.92  ? 236 GLY C CA  1 
ATOM   5495  C C   . GLY C 1 34  ? -3.839  2.980   64.578 1.00 38.64  ? 236 GLY C C   1 
ATOM   5496  O O   . GLY C 1 34  ? -3.609  2.940   63.373 1.00 39.65  ? 236 GLY C O   1 
ATOM   5497  N N   . ASP C 1 35  ? -5.066  2.981   65.083 1.00 35.71  ? 237 ASP C N   1 
ATOM   5498  C CA  . ASP C 1 35  ? -6.260  2.909   64.256 1.00 36.08  ? 237 ASP C CA  1 
ATOM   5499  C C   . ASP C 1 35  ? -6.854  4.279   63.976 1.00 33.37  ? 237 ASP C C   1 
ATOM   5500  O O   . ASP C 1 35  ? -7.987  4.380   63.521 1.00 32.35  ? 237 ASP C O   1 
ATOM   5501  C CB  . ASP C 1 35  ? -7.312  2.019   64.909 1.00 36.71  ? 237 ASP C CB  1 
ATOM   5502  C CG  . ASP C 1 35  ? -7.696  2.493   66.290 1.00 43.56  ? 237 ASP C CG  1 
ATOM   5503  O OD1 . ASP C 1 35  ? -6.790  2.869   67.061 1.00 46.85  ? 237 ASP C OD1 1 
ATOM   5504  O OD2 . ASP C 1 35  ? -8.902  2.483   66.609 1.00 45.73  ? 237 ASP C OD2 1 
ATOM   5505  N N   . ARG C 1 36  ? -6.109  5.331   64.293 1.00 36.34  ? 238 ARG C N   1 
ATOM   5506  C CA  . ARG C 1 36  ? -6.585  6.687   64.065 1.00 34.68  ? 238 ARG C CA  1 
ATOM   5507  C C   . ARG C 1 36  ? -5.614  7.526   63.254 1.00 30.88  ? 238 ARG C C   1 
ATOM   5508  O O   . ARG C 1 36  ? -4.421  7.276   63.239 1.00 30.32  ? 238 ARG C O   1 
ATOM   5509  C CB  . ARG C 1 36  ? -6.886  7.384   65.389 1.00 33.42  ? 238 ARG C CB  1 
ATOM   5510  C CG  . ARG C 1 36  ? -8.099  6.822   66.103 1.00 43.55  ? 238 ARG C CG  1 
ATOM   5511  C CD  . ARG C 1 36  ? -8.810  7.885   66.914 1.00 51.48  ? 238 ARG C CD  1 
ATOM   5512  N NE  . ARG C 1 36  ? -10.194 7.511   67.183 1.00 59.79  ? 238 ARG C NE  1 
ATOM   5513  C CZ  . ARG C 1 36  ? -10.667 7.192   68.382 1.00 62.91  ? 238 ARG C CZ  1 
ATOM   5514  N NH1 . ARG C 1 36  ? -9.871  7.209   69.440 1.00 64.73  ? 238 ARG C NH1 1 
ATOM   5515  N NH2 . ARG C 1 36  ? -11.941 6.861   68.523 1.00 62.69  ? 238 ARG C NH2 1 
ATOM   5516  N N   . VAL C 1 37  ? -6.153  8.498   62.534 1.00 30.18  ? 239 VAL C N   1 
ATOM   5517  C CA  . VAL C 1 37  ? -5.349  9.403   61.738 1.00 26.82  ? 239 VAL C CA  1 
ATOM   5518  C C   . VAL C 1 37  ? -5.688  10.812  62.157 1.00 25.52  ? 239 VAL C C   1 
ATOM   5519  O O   . VAL C 1 37  ? -6.857  11.154  62.267 1.00 24.38  ? 239 VAL C O   1 
ATOM   5520  C CB  . VAL C 1 37  ? -5.703  9.321   60.248 1.00 22.73  ? 239 VAL C CB  1 
ATOM   5521  C CG1 . VAL C 1 37  ? -4.656  10.040  59.415 1.00 20.21  ? 239 VAL C CG1 1 
ATOM   5522  C CG2 . VAL C 1 37  ? -5.869  7.884   59.809 1.00 25.43  ? 239 VAL C CG2 1 
ATOM   5523  N N   . ILE C 1 38  ? -4.685  11.636  62.411 1.00 27.48  ? 240 ILE C N   1 
ATOM   5524  C CA  . ILE C 1 38  ? -4.982  13.011  62.744 1.00 26.30  ? 240 ILE C CA  1 
ATOM   5525  C C   . ILE C 1 38  ? -4.432  13.841  61.606 1.00 27.03  ? 240 ILE C C   1 
ATOM   5526  O O   . ILE C 1 38  ? -3.260  13.768  61.295 1.00 27.83  ? 240 ILE C O   1 
ATOM   5527  C CB  . ILE C 1 38  ? -4.369  13.445  64.083 1.00 30.92  ? 240 ILE C CB  1 
ATOM   5528  C CG1 . ILE C 1 38  ? -4.971  12.638  65.227 1.00 30.69  ? 240 ILE C CG1 1 
ATOM   5529  C CG2 . ILE C 1 38  ? -4.625  14.920  64.329 1.00 28.72  ? 240 ILE C CG2 1 
ATOM   5530  C CD1 . ILE C 1 38  ? -4.618  13.170  66.595 1.00 32.76  ? 240 ILE C CD1 1 
ATOM   5531  N N   . THR C 1 39  ? -5.288  14.625  60.976 1.00 27.78  ? 241 THR C N   1 
ATOM   5532  C CA  . THR C 1 39  ? -4.859  15.460  59.872 1.00 28.25  ? 241 THR C CA  1 
ATOM   5533  C C   . THR C 1 39  ? -4.947  16.910  60.293 1.00 28.41  ? 241 THR C C   1 
ATOM   5534  O O   . THR C 1 39  ? -5.934  17.329  60.886 1.00 28.71  ? 241 THR C O   1 
ATOM   5535  C CB  . THR C 1 39  ? -5.717  15.232  58.616 1.00 24.03  ? 241 THR C CB  1 
ATOM   5536  O OG1 . THR C 1 39  ? -7.094  15.455  58.930 1.00 25.25  ? 241 THR C OG1 1 
ATOM   5537  C CG2 . THR C 1 39  ? -5.548  13.820  58.111 1.00 22.34  ? 241 THR C CG2 1 
ATOM   5538  N N   . THR C 1 40  ? -3.903  17.673  60.000 1.00 31.09  ? 242 THR C N   1 
ATOM   5539  C CA  . THR C 1 40  ? -3.883  19.081  60.365 1.00 32.80  ? 242 THR C CA  1 
ATOM   5540  C C   . THR C 1 40  ? -3.593  19.907  59.124 1.00 31.26  ? 242 THR C C   1 
ATOM   5541  O O   . THR C 1 40  ? -2.655  19.606  58.382 1.00 29.84  ? 242 THR C O   1 
ATOM   5542  C CB  . THR C 1 40  ? -2.836  19.362  61.445 1.00 30.43  ? 242 THR C CB  1 
ATOM   5543  O OG1 . THR C 1 40  ? -3.064  18.503  62.567 1.00 36.91  ? 242 THR C OG1 1 
ATOM   5544  C CG2 . THR C 1 40  ? -2.956  20.791  61.909 1.00 32.58  ? 242 THR C CG2 1 
ATOM   5545  N N   . SER C 1 41  ? -4.398  20.941  58.902 1.00 31.64  ? 243 SER C N   1 
ATOM   5546  C CA  . SER C 1 41  ? -4.314  21.762  57.703 1.00 31.76  ? 243 SER C CA  1 
ATOM   5547  C C   . SER C 1 41  ? -4.335  23.228  58.101 1.00 31.11  ? 243 SER C C   1 
ATOM   5548  O O   . SER C 1 41  ? -5.251  23.665  58.802 1.00 32.06  ? 243 SER C O   1 
ATOM   5549  C CB  . SER C 1 41  ? -5.475  21.463  56.749 1.00 27.26  ? 243 SER C CB  1 
ATOM   5550  O OG  . SER C 1 41  ? -5.434  20.123  56.294 1.00 32.95  ? 243 SER C OG  1 
ATOM   5551  N N   . THR C 1 42  ? -3.341  23.986  57.645 1.00 30.77  ? 244 THR C N   1 
ATOM   5552  C CA  . THR C 1 42  ? -3.274  25.420  57.890 1.00 29.28  ? 244 THR C CA  1 
ATOM   5553  C C   . THR C 1 42  ? -3.218  26.135  56.547 1.00 29.57  ? 244 THR C C   1 
ATOM   5554  O O   . THR C 1 42  ? -2.554  25.664  55.621 1.00 31.34  ? 244 THR C O   1 
ATOM   5555  C CB  . THR C 1 42  ? -2.061  25.787  58.751 1.00 31.94  ? 244 THR C CB  1 
ATOM   5556  O OG1 . THR C 1 42  ? -2.079  25.010  59.953 1.00 31.78  ? 244 THR C OG1 1 
ATOM   5557  C CG2 . THR C 1 42  ? -2.121  27.245  59.147 1.00 31.16  ? 244 THR C CG2 1 
ATOM   5558  N N   . ARG C 1 43  ? -3.936  27.251  56.433 1.00 31.62  ? 245 ARG C N   1 
ATOM   5559  C CA  . ARG C 1 43  ? -3.976  28.023  55.198 1.00 30.86  ? 245 ARG C CA  1 
ATOM   5560  C C   . ARG C 1 43  ? -3.866  29.507  55.513 1.00 30.47  ? 245 ARG C C   1 
ATOM   5561  O O   . ARG C 1 43  ? -3.732  29.912  56.669 1.00 30.67  ? 245 ARG C O   1 
ATOM   5562  C CB  . ARG C 1 43  ? -5.268  27.780  54.397 1.00 22.88  ? 245 ARG C CB  1 
ATOM   5563  C CG  . ARG C 1 43  ? -5.503  26.350  53.955 1.00 25.03  ? 245 ARG C CG  1 
ATOM   5564  C CD  . ARG C 1 43  ? -4.505  25.911  52.900 1.00 25.91  ? 245 ARG C CD  1 
ATOM   5565  N NE  . ARG C 1 43  ? -4.772  24.550  52.450 1.00 30.29  ? 245 ARG C NE  1 
ATOM   5566  C CZ  . ARG C 1 43  ? -4.270  23.465  53.023 1.00 30.95  ? 245 ARG C CZ  1 
ATOM   5567  N NH1 . ARG C 1 43  ? -4.566  22.265  52.551 1.00 31.85  ? 245 ARG C NH1 1 
ATOM   5568  N NH2 . ARG C 1 43  ? -3.479  23.579  54.078 1.00 31.88  ? 245 ARG C NH2 1 
ATOM   5569  N N   . THR C 1 44  ? -3.927  30.316  54.460 1.00 31.32  ? 246 THR C N   1 
ATOM   5570  C CA  . THR C 1 44  ? -4.012  31.765  54.572 1.00 31.89  ? 246 THR C CA  1 
ATOM   5571  C C   . THR C 1 44  ? -5.253  32.241  53.827 1.00 32.62  ? 246 THR C C   1 
ATOM   5572  O O   . THR C 1 44  ? -5.548  31.752  52.733 1.00 32.60  ? 246 THR C O   1 
ATOM   5573  C CB  . THR C 1 44  ? -2.753  32.434  54.016 1.00 32.29  ? 246 THR C CB  1 
ATOM   5574  O OG1 . THR C 1 44  ? -1.613  31.992  54.761 1.00 33.79  ? 246 THR C OG1 1 
ATOM   5575  C CG2 . THR C 1 44  ? -2.849  33.942  54.128 1.00 32.15  ? 246 THR C CG2 1 
ATOM   5576  N N   . TRP C 1 45  ? -5.983  33.179  54.426 1.00 32.70  ? 247 TRP C N   1 
ATOM   5577  C CA  . TRP C 1 45  ? -7.271  33.618  53.912 1.00 32.36  ? 247 TRP C CA  1 
ATOM   5578  C C   . TRP C 1 45  ? -7.322  35.135  53.809 1.00 33.60  ? 247 TRP C C   1 
ATOM   5579  O O   . TRP C 1 45  ? -6.535  35.843  54.440 1.00 33.32  ? 247 TRP C O   1 
ATOM   5580  C CB  . TRP C 1 45  ? -8.406  33.124  54.809 1.00 34.43  ? 247 TRP C CB  1 
ATOM   5581  C CG  . TRP C 1 45  ? -8.224  33.501  56.243 1.00 34.70  ? 247 TRP C CG  1 
ATOM   5582  C CD1 . TRP C 1 45  ? -7.496  32.830  57.172 1.00 34.43  ? 247 TRP C CD1 1 
ATOM   5583  C CD2 . TRP C 1 45  ? -8.785  34.633  56.914 1.00 34.83  ? 247 TRP C CD2 1 
ATOM   5584  N NE1 . TRP C 1 45  ? -7.566  33.468  58.383 1.00 33.11  ? 247 TRP C NE1 1 
ATOM   5585  C CE2 . TRP C 1 45  ? -8.349  34.583  58.250 1.00 33.47  ? 247 TRP C CE2 1 
ATOM   5586  C CE3 . TRP C 1 45  ? -9.609  35.688  56.514 1.00 35.70  ? 247 TRP C CE3 1 
ATOM   5587  C CZ2 . TRP C 1 45  ? -8.709  35.544  59.189 1.00 33.37  ? 247 TRP C CZ2 1 
ATOM   5588  C CZ3 . TRP C 1 45  ? -9.969  36.638  57.447 1.00 35.17  ? 247 TRP C CZ3 1 
ATOM   5589  C CH2 . TRP C 1 45  ? -9.518  36.561  58.769 1.00 34.05  ? 247 TRP C CH2 1 
ATOM   5590  N N   . ALA C 1 46  ? -8.259  35.625  52.999 1.00 33.33  ? 248 ALA C N   1 
ATOM   5591  C CA  . ALA C 1 46  ? -8.549  37.049  52.890 1.00 33.91  ? 248 ALA C CA  1 
ATOM   5592  C C   . ALA C 1 46  ? -10.055 37.240  52.809 1.00 33.96  ? 248 ALA C C   1 
ATOM   5593  O O   . ALA C 1 46  ? -10.718 36.629  51.966 1.00 34.51  ? 248 ALA C O   1 
ATOM   5594  C CB  . ALA C 1 46  ? -7.867  37.674  51.668 1.00 32.19  ? 248 ALA C CB  1 
ATOM   5595  N N   . LEU C 1 47  ? -10.589 38.091  53.681 1.00 33.53  ? 249 LEU C N   1 
ATOM   5596  C CA  . LEU C 1 47  ? -12.021 38.348  53.749 1.00 32.95  ? 249 LEU C CA  1 
ATOM   5597  C C   . LEU C 1 47  ? -12.316 39.788  53.360 1.00 33.79  ? 249 LEU C C   1 
ATOM   5598  O O   . LEU C 1 47  ? -12.042 40.706  54.151 1.00 34.25  ? 249 LEU C O   1 
ATOM   5599  C CB  . LEU C 1 47  ? -12.544 38.062  55.155 1.00 35.56  ? 249 LEU C CB  1 
ATOM   5600  C CG  . LEU C 1 47  ? -14.006 38.392  55.438 1.00 34.85  ? 249 LEU C CG  1 
ATOM   5601  C CD1 . LEU C 1 47  ? -14.924 37.592  54.543 1.00 34.85  ? 249 LEU C CD1 1 
ATOM   5602  C CD2 . LEU C 1 47  ? -14.306 38.112  56.890 1.00 35.76  ? 249 LEU C CD2 1 
ATOM   5603  N N   . PRO C 1 48  ? -12.866 40.037  52.178 1.00 35.13  ? 250 PRO C N   1 
ATOM   5604  C CA  . PRO C 1 48  ? -13.301 41.395  51.830 1.00 35.95  ? 250 PRO C CA  1 
ATOM   5605  C C   . PRO C 1 48  ? -14.625 41.767  52.473 1.00 37.13  ? 250 PRO C C   1 
ATOM   5606  O O   . PRO C 1 48  ? -15.362 40.896  52.941 1.00 37.69  ? 250 PRO C O   1 
ATOM   5607  C CB  . PRO C 1 48  ? -13.425 41.336  50.305 1.00 35.04  ? 250 PRO C CB  1 
ATOM   5608  C CG  . PRO C 1 48  ? -13.774 39.924  50.036 1.00 34.02  ? 250 PRO C CG  1 
ATOM   5609  C CD  . PRO C 1 48  ? -13.030 39.102  51.053 1.00 33.97  ? 250 PRO C CD  1 
ATOM   5610  N N   . THR C 1 49  ? -14.936 43.060  52.503 1.00 38.12  ? 251 THR C N   1 
ATOM   5611  C CA  . THR C 1 49  ? -16.280 43.489  52.858 1.00 38.45  ? 251 THR C CA  1 
ATOM   5612  C C   . THR C 1 49  ? -17.241 43.208  51.710 1.00 38.57  ? 251 THR C C   1 
ATOM   5613  O O   . THR C 1 49  ? -17.011 43.623  50.571 1.00 38.23  ? 251 THR C O   1 
ATOM   5614  C CB  . THR C 1 49  ? -16.296 44.978  53.196 1.00 42.04  ? 251 THR C CB  1 
ATOM   5615  O OG1 . THR C 1 49  ? -15.487 45.220  54.354 1.00 43.22  ? 251 THR C OG1 1 
ATOM   5616  C CG2 . THR C 1 49  ? -17.717 45.442  53.460 1.00 40.45  ? 251 THR C CG2 1 
ATOM   5617  N N   . TYR C 1 50  ? -18.323 42.498  52.013 1.00 36.92  ? 252 TYR C N   1 
ATOM   5618  C CA  . TYR C 1 50  ? -19.319 42.120  51.022 1.00 37.91  ? 252 TYR C CA  1 
ATOM   5619  C C   . TYR C 1 50  ? -20.536 43.031  51.109 1.00 39.23  ? 252 TYR C C   1 
ATOM   5620  O O   . TYR C 1 50  ? -20.988 43.377  52.205 1.00 40.63  ? 252 TYR C O   1 
ATOM   5621  C CB  . TYR C 1 50  ? -19.756 40.666  51.200 1.00 34.04  ? 252 TYR C CB  1 
ATOM   5622  C CG  . TYR C 1 50  ? -18.695 39.635  50.893 1.00 32.56  ? 252 TYR C CG  1 
ATOM   5623  C CD1 . TYR C 1 50  ? -18.454 39.237  49.588 1.00 32.37  ? 252 TYR C CD1 1 
ATOM   5624  C CD2 . TYR C 1 50  ? -17.973 39.023  51.906 1.00 31.96  ? 252 TYR C CD2 1 
ATOM   5625  C CE1 . TYR C 1 50  ? -17.503 38.290  49.296 1.00 31.35  ? 252 TYR C CE1 1 
ATOM   5626  C CE2 . TYR C 1 50  ? -17.020 38.068  51.622 1.00 31.92  ? 252 TYR C CE2 1 
ATOM   5627  C CZ  . TYR C 1 50  ? -16.790 37.709  50.314 1.00 32.11  ? 252 TYR C CZ  1 
ATOM   5628  O OH  . TYR C 1 50  ? -15.846 36.760  50.011 1.00 34.13  ? 252 TYR C OH  1 
ATOM   5629  N N   . ASN C 1 51  ? -21.053 43.420  49.940 1.00 41.92  ? 253 ASN C N   1 
ATOM   5630  C CA  . ASN C 1 51  ? -22.271 44.229  49.820 1.00 43.77  ? 253 ASN C CA  1 
ATOM   5631  C C   . ASN C 1 51  ? -22.156 45.562  50.553 1.00 45.08  ? 253 ASN C C   1 
ATOM   5632  O O   . ASN C 1 51  ? -23.165 46.147  50.949 1.00 45.95  ? 253 ASN C O   1 
ATOM   5633  C CB  . ASN C 1 51  ? -23.506 43.471  50.312 1.00 36.97  ? 253 ASN C CB  1 
ATOM   5634  C CG  . ASN C 1 51  ? -23.959 42.399  49.349 1.00 37.48  ? 253 ASN C CG  1 
ATOM   5635  O OD1 . ASN C 1 51  ? -23.638 42.436  48.163 1.00 39.05  ? 253 ASN C OD1 1 
ATOM   5636  N ND2 . ASN C 1 51  ? -24.738 41.450  49.850 1.00 35.78  ? 253 ASN C ND2 1 
ATOM   5637  N N   . ASN C 1 52  ? -20.930 46.054  50.730 1.00 43.88  ? 254 ASN C N   1 
ATOM   5638  C CA  . ASN C 1 52  ? -20.691 47.333  51.398 1.00 46.15  ? 254 ASN C CA  1 
ATOM   5639  C C   . ASN C 1 52  ? -21.364 47.378  52.769 1.00 45.64  ? 254 ASN C C   1 
ATOM   5640  O O   . ASN C 1 52  ? -22.016 48.359  53.130 1.00 45.25  ? 254 ASN C O   1 
ATOM   5641  C CB  . ASN C 1 52  ? -21.160 48.500  50.528 1.00 42.03  ? 254 ASN C CB  1 
ATOM   5642  C CG  . ASN C 1 52  ? -20.323 48.670  49.281 1.00 47.60  ? 254 ASN C CG  1 
ATOM   5643  O OD1 . ASN C 1 52  ? -19.219 49.207  49.331 1.00 50.96  ? 254 ASN C OD1 1 
ATOM   5644  N ND2 . ASN C 1 52  ? -20.845 48.209  48.152 1.00 50.20  ? 254 ASN C ND2 1 
ATOM   5645  N N   . HIS C 1 53  ? -21.215 46.293  53.531 1.00 42.84  ? 255 HIS C N   1 
ATOM   5646  C CA  . HIS C 1 53  ? -21.769 46.145  54.874 1.00 42.90  ? 255 HIS C CA  1 
ATOM   5647  C C   . HIS C 1 53  ? -23.295 46.127  54.893 1.00 41.68  ? 255 HIS C C   1 
ATOM   5648  O O   . HIS C 1 53  ? -23.905 46.512  55.895 1.00 43.08  ? 255 HIS C O   1 
ATOM   5649  C CB  . HIS C 1 53  ? -21.259 47.248  55.810 1.00 44.88  ? 255 HIS C CB  1 
ATOM   5650  C CG  . HIS C 1 53  ? -19.768 47.295  55.937 1.00 48.10  ? 255 HIS C CG  1 
ATOM   5651  N ND1 . HIS C 1 53  ? -19.050 46.348  56.635 1.00 50.91  ? 255 HIS C ND1 1 
ATOM   5652  C CD2 . HIS C 1 53  ? -18.859 48.171  55.448 1.00 47.63  ? 255 HIS C CD2 1 
ATOM   5653  C CE1 . HIS C 1 53  ? -17.764 46.643  56.577 1.00 51.23  ? 255 HIS C CE1 1 
ATOM   5654  N NE2 . HIS C 1 53  ? -17.621 47.744  55.861 1.00 49.82  ? 255 HIS C NE2 1 
ATOM   5655  N N   . LEU C 1 54  ? -23.934 45.673  53.820 1.00 42.89  ? 256 LEU C N   1 
ATOM   5656  C CA  . LEU C 1 54  ? -25.384 45.690  53.715 1.00 39.49  ? 256 LEU C CA  1 
ATOM   5657  C C   . LEU C 1 54  ? -25.941 44.287  53.519 1.00 39.45  ? 256 LEU C C   1 
ATOM   5658  O O   . LEU C 1 54  ? -25.358 43.460  52.814 1.00 40.44  ? 256 LEU C O   1 
ATOM   5659  C CB  . LEU C 1 54  ? -25.841 46.573  52.551 1.00 41.58  ? 256 LEU C CB  1 
ATOM   5660  C CG  . LEU C 1 54  ? -25.609 48.079  52.644 1.00 39.04  ? 256 LEU C CG  1 
ATOM   5661  C CD1 . LEU C 1 54  ? -25.926 48.737  51.316 1.00 37.37  ? 256 LEU C CD1 1 
ATOM   5662  C CD2 . LEU C 1 54  ? -26.470 48.673  53.746 1.00 37.91  ? 256 LEU C CD2 1 
ATOM   5663  N N   . TYR C 1 55  ? -27.077 44.028  54.159 1.00 37.31  ? 257 TYR C N   1 
ATOM   5664  C CA  . TYR C 1 55  ? -27.917 42.898  53.792 1.00 36.74  ? 257 TYR C CA  1 
ATOM   5665  C C   . TYR C 1 55  ? -28.815 43.306  52.635 1.00 36.84  ? 257 TYR C C   1 
ATOM   5666  O O   . TYR C 1 55  ? -29.482 44.342  52.691 1.00 38.10  ? 257 TYR C O   1 
ATOM   5667  C CB  . TYR C 1 55  ? -28.777 42.449  54.971 1.00 37.42  ? 257 TYR C CB  1 
ATOM   5668  C CG  . TYR C 1 55  ? -28.031 41.819  56.123 1.00 38.36  ? 257 TYR C CG  1 
ATOM   5669  C CD1 . TYR C 1 55  ? -27.830 40.449  56.174 1.00 38.38  ? 257 TYR C CD1 1 
ATOM   5670  C CD2 . TYR C 1 55  ? -27.543 42.590  57.164 1.00 38.35  ? 257 TYR C CD2 1 
ATOM   5671  C CE1 . TYR C 1 55  ? -27.163 39.864  57.227 1.00 39.48  ? 257 TYR C CE1 1 
ATOM   5672  C CE2 . TYR C 1 55  ? -26.869 42.013  58.221 1.00 40.04  ? 257 TYR C CE2 1 
ATOM   5673  C CZ  . TYR C 1 55  ? -26.684 40.649  58.247 1.00 40.61  ? 257 TYR C CZ  1 
ATOM   5674  O OH  . TYR C 1 55  ? -26.013 40.063  59.295 1.00 42.85  ? 257 TYR C OH  1 
ATOM   5675  N N   . LYS C 1 56  ? -28.834 42.495  51.582 1.00 35.89  ? 258 LYS C N   1 
ATOM   5676  C CA  . LYS C 1 56  ? -29.636 42.817  50.411 1.00 35.75  ? 258 LYS C CA  1 
ATOM   5677  C C   . LYS C 1 56  ? -30.420 41.599  49.950 1.00 35.09  ? 258 LYS C C   1 
ATOM   5678  O O   . LYS C 1 56  ? -29.871 40.501  49.829 1.00 35.87  ? 258 LYS C O   1 
ATOM   5679  C CB  . LYS C 1 56  ? -28.766 43.356  49.267 1.00 32.96  ? 258 LYS C CB  1 
ATOM   5680  C CG  . LYS C 1 56  ? -28.205 44.739  49.553 1.00 36.41  ? 258 LYS C CG  1 
ATOM   5681  C CD  . LYS C 1 56  ? -27.571 45.375  48.330 1.00 37.40  ? 258 LYS C CD  1 
ATOM   5682  C CE  . LYS C 1 56  ? -26.324 44.638  47.895 1.00 39.46  ? 258 LYS C CE  1 
ATOM   5683  N NZ  . LYS C 1 56  ? -25.644 45.344  46.778 1.00 42.29  ? 258 LYS C NZ  1 
ATOM   5684  N N   . GLN C 1 57  ? -31.711 41.809  49.712 1.00 36.58  ? 259 GLN C N   1 
ATOM   5685  C CA  . GLN C 1 57  ? -32.581 40.803  49.116 1.00 36.34  ? 259 GLN C CA  1 
ATOM   5686  C C   . GLN C 1 57  ? -32.084 40.428  47.727 1.00 36.93  ? 259 GLN C C   1 
ATOM   5687  O O   . GLN C 1 57  ? -31.561 41.279  46.999 1.00 37.08  ? 259 GLN C O   1 
ATOM   5688  C CB  . GLN C 1 57  ? -34.008 41.339  49.043 1.00 35.11  ? 259 GLN C CB  1 
ATOM   5689  C CG  . GLN C 1 57  ? -34.987 40.437  48.319 1.00 35.86  ? 259 GLN C CG  1 
ATOM   5690  C CD  . GLN C 1 57  ? -36.392 40.968  48.361 1.00 38.19  ? 259 GLN C CD  1 
ATOM   5691  O OE1 . GLN C 1 57  ? -36.702 41.868  49.139 1.00 41.81  ? 259 GLN C OE1 1 
ATOM   5692  N NE2 . GLN C 1 57  ? -37.239 40.463  47.481 1.00 36.56  ? 259 GLN C NE2 1 
ATOM   5693  N N   . ILE C 1 58  ? -32.252 39.161  47.356 1.00 38.67  ? 260 ILE C N   1 
ATOM   5694  C CA  . ILE C 1 58  ? -31.907 38.665  46.029 1.00 39.46  ? 260 ILE C CA  1 
ATOM   5695  C C   . ILE C 1 58  ? -33.020 37.747  45.541 1.00 42.38  ? 260 ILE C C   1 
ATOM   5696  O O   . ILE C 1 58  ? -33.617 37.006  46.331 1.00 43.15  ? 260 ILE C O   1 
ATOM   5697  C CB  . ILE C 1 58  ? -30.551 37.936  46.031 1.00 39.11  ? 260 ILE C CB  1 
ATOM   5698  C CG1 . ILE C 1 58  ? -30.553 36.804  47.057 1.00 38.07  ? 260 ILE C CG1 1 
ATOM   5699  C CG2 . ILE C 1 58  ? -29.414 38.909  46.283 1.00 35.92  ? 260 ILE C CG2 1 
ATOM   5700  C CD1 . ILE C 1 58  ? -29.329 35.945  47.011 1.00 37.48  ? 260 ILE C CD1 1 
ATOM   5701  N N   . SER C 1 59  ? -33.312 37.817  44.246 1.00 46.33  ? 261 SER C N   1 
ATOM   5702  C CA  . SER C 1 59  ? -34.236 36.905  43.589 1.00 48.72  ? 261 SER C CA  1 
ATOM   5703  C C   . SER C 1 59  ? -33.938 36.916  42.097 1.00 51.34  ? 261 SER C C   1 
ATOM   5704  O O   . SER C 1 59  ? -33.241 37.801  41.591 1.00 51.22  ? 261 SER C O   1 
ATOM   5705  C CB  . SER C 1 59  ? -35.696 37.276  43.864 1.00 50.37  ? 261 SER C CB  1 
ATOM   5706  O OG  . SER C 1 59  ? -36.009 38.549  43.332 1.00 49.48  ? 261 SER C OG  1 
ATOM   5707  N N   . ASN C 1 60  ? -34.465 35.915  41.386 1.00 49.53  ? 262 ASN C N   1 
ATOM   5708  C CA  . ASN C 1 60  ? -34.189 35.801  39.955 1.00 52.93  ? 262 ASN C CA  1 
ATOM   5709  C C   . ASN C 1 60  ? -34.677 37.020  39.184 1.00 55.81  ? 262 ASN C C   1 
ATOM   5710  O O   . ASN C 1 60  ? -34.266 37.235  38.038 1.00 56.14  ? 262 ASN C O   1 
ATOM   5711  C CB  . ASN C 1 60  ? -34.817 34.523  39.392 1.00 52.38  ? 262 ASN C CB  1 
ATOM   5712  C CG  . ASN C 1 60  ? -36.339 34.525  39.451 1.00 51.87  ? 262 ASN C CG  1 
ATOM   5713  O OD1 . ASN C 1 60  ? -36.989 35.553  39.294 1.00 51.41  ? 262 ASN C OD1 1 
ATOM   5714  N ND2 . ASN C 1 60  ? -36.911 33.359  39.662 1.00 51.92  ? 262 ASN C ND2 1 
ATOM   5715  N N   . SER C 1 61  ? -35.571 37.811  39.786 1.00 54.70  ? 263 SER C N   1 
ATOM   5716  C CA  . SER C 1 61  ? -36.036 39.037  39.147 1.00 58.33  ? 263 SER C CA  1 
ATOM   5717  C C   . SER C 1 61  ? -34.875 39.981  38.864 1.00 60.48  ? 263 SER C C   1 
ATOM   5718  O O   . SER C 1 61  ? -34.909 40.749  37.895 1.00 61.09  ? 263 SER C O   1 
ATOM   5719  C CB  . SER C 1 61  ? -37.087 39.714  40.027 1.00 58.37  ? 263 SER C CB  1 
ATOM   5720  O OG  . SER C 1 61  ? -37.545 40.922  39.448 1.00 59.75  ? 263 SER C OG  1 
ATOM   5721  N N   . THR C 1 62  ? -33.835 39.938  39.699 1.00 61.43  ? 264 THR C N   1 
ATOM   5722  C CA  . THR C 1 62  ? -32.623 40.692  39.404 1.00 63.05  ? 264 THR C CA  1 
ATOM   5723  C C   . THR C 1 62  ? -31.922 40.132  38.173 1.00 64.83  ? 264 THR C C   1 
ATOM   5724  O O   . THR C 1 62  ? -31.322 40.881  37.394 1.00 64.46  ? 264 THR C O   1 
ATOM   5725  C CB  . THR C 1 62  ? -31.684 40.676  40.609 1.00 60.24  ? 264 THR C CB  1 
ATOM   5726  O OG1 . THR C 1 62  ? -31.337 39.323  40.928 1.00 58.96  ? 264 THR C OG1 1 
ATOM   5727  C CG2 . THR C 1 62  ? -32.358 41.310  41.815 1.00 59.71  ? 264 THR C CG2 1 
ATOM   5728  N N   . SER C 1 63  ? -31.992 38.812  37.979 1.00 65.61  ? 265 SER C N   1 
ATOM   5729  C CA  . SER C 1 63  ? -31.391 38.178  36.813 1.00 67.40  ? 265 SER C CA  1 
ATOM   5730  C C   . SER C 1 63  ? -32.380 37.985  35.670 1.00 68.95  ? 265 SER C C   1 
ATOM   5731  O O   . SER C 1 63  ? -31.992 37.454  34.624 1.00 69.35  ? 265 SER C O   1 
ATOM   5732  C CB  . SER C 1 63  ? -30.784 36.830  37.205 1.00 64.45  ? 265 SER C CB  1 
ATOM   5733  O OG  . SER C 1 63  ? -29.720 37.001  38.125 1.00 66.07  ? 265 SER C OG  1 
ATOM   5734  N N   . GLY C 1 64  ? -33.635 38.399  35.839 1.00 65.18  ? 266 GLY C N   1 
ATOM   5735  C CA  . GLY C 1 64  ? -34.626 38.359  34.787 1.00 66.45  ? 266 GLY C CA  1 
ATOM   5736  C C   . GLY C 1 64  ? -35.707 37.309  34.954 1.00 67.32  ? 266 GLY C C   1 
ATOM   5737  O O   . GLY C 1 64  ? -36.739 37.398  34.279 1.00 67.98  ? 266 GLY C O   1 
ATOM   5738  N N   . GLY C 1 65  ? -35.508 36.331  35.836 1.00 67.21  ? 267 GLY C N   1 
ATOM   5739  C CA  . GLY C 1 65  ? -36.513 35.311  36.081 1.00 66.07  ? 267 GLY C CA  1 
ATOM   5740  C C   . GLY C 1 65  ? -36.923 34.541  34.842 1.00 65.05  ? 267 GLY C C   1 
ATOM   5741  O O   . GLY C 1 65  ? -38.108 34.493  34.498 1.00 64.54  ? 267 GLY C O   1 
ATOM   5742  N N   . SER C 1 66  ? -35.950 33.933  34.162 1.00 67.41  ? 268 SER C N   1 
ATOM   5743  C CA  . SER C 1 66  ? -36.231 33.317  32.869 1.00 65.67  ? 268 SER C CA  1 
ATOM   5744  C C   . SER C 1 66  ? -37.059 32.046  33.015 1.00 64.03  ? 268 SER C C   1 
ATOM   5745  O O   . SER C 1 66  ? -38.060 31.867  32.311 1.00 63.41  ? 268 SER C O   1 
ATOM   5746  C CB  . SER C 1 66  ? -34.923 33.025  32.136 1.00 68.10  ? 268 SER C CB  1 
ATOM   5747  O OG  . SER C 1 66  ? -34.240 34.226  31.825 1.00 67.69  ? 268 SER C OG  1 
ATOM   5748  N N   . SER C 1 67  ? -36.663 31.153  33.918 1.00 60.32  ? 269 SER C N   1 
ATOM   5749  C CA  . SER C 1 67  ? -37.265 29.833  34.018 1.00 57.51  ? 269 SER C CA  1 
ATOM   5750  C C   . SER C 1 67  ? -38.005 29.674  35.339 1.00 55.81  ? 269 SER C C   1 
ATOM   5751  O O   . SER C 1 67  ? -37.688 30.331  36.334 1.00 54.85  ? 269 SER C O   1 
ATOM   5752  C CB  . SER C 1 67  ? -36.207 28.732  33.890 1.00 52.39  ? 269 SER C CB  1 
ATOM   5753  O OG  . SER C 1 67  ? -36.790 27.450  34.038 1.00 50.99  ? 269 SER C OG  1 
ATOM   5754  N N   . ASN C 1 68  ? -39.006 28.791  35.330 1.00 54.37  ? 270 ASN C N   1 
ATOM   5755  C CA  . ASN C 1 68  ? -39.703 28.450  36.565 1.00 52.63  ? 270 ASN C CA  1 
ATOM   5756  C C   . ASN C 1 68  ? -38.876 27.475  37.394 1.00 50.49  ? 270 ASN C C   1 
ATOM   5757  O O   . ASN C 1 68  ? -38.850 27.557  38.628 1.00 49.51  ? 270 ASN C O   1 
ATOM   5758  C CB  . ASN C 1 68  ? -41.077 27.863  36.235 1.00 55.29  ? 270 ASN C CB  1 
ATOM   5759  C CG  . ASN C 1 68  ? -41.978 27.733  37.453 1.00 56.98  ? 270 ASN C CG  1 
ATOM   5760  O OD1 . ASN C 1 68  ? -41.520 27.730  38.593 1.00 56.48  ? 270 ASN C OD1 1 
ATOM   5761  N ND2 . ASN C 1 68  ? -43.278 27.623  37.207 1.00 57.25  ? 270 ASN C ND2 1 
ATOM   5762  N N   . ASP C 1 69  ? -38.180 26.552  36.729 1.00 50.77  ? 271 ASP C N   1 
ATOM   5763  C CA  . ASP C 1 69  ? -37.342 25.596  37.443 1.00 48.40  ? 271 ASP C CA  1 
ATOM   5764  C C   . ASP C 1 69  ? -36.162 26.288  38.110 1.00 46.02  ? 271 ASP C C   1 
ATOM   5765  O O   . ASP C 1 69  ? -35.605 25.779  39.090 1.00 45.86  ? 271 ASP C O   1 
ATOM   5766  C CB  . ASP C 1 69  ? -36.852 24.516  36.480 1.00 43.76  ? 271 ASP C CB  1 
ATOM   5767  C CG  . ASP C 1 69  ? -37.969 23.624  35.990 1.00 46.27  ? 271 ASP C CG  1 
ATOM   5768  O OD1 . ASP C 1 69  ? -39.046 23.617  36.619 1.00 47.01  ? 271 ASP C OD1 1 
ATOM   5769  O OD2 . ASP C 1 69  ? -37.773 22.933  34.969 1.00 47.13  ? 271 ASP C OD2 1 
ATOM   5770  N N   . ASN C 1 70  ? -35.760 27.448  37.588 1.00 45.51  ? 272 ASN C N   1 
ATOM   5771  C CA  . ASN C 1 70  ? -34.606 28.149  38.137 1.00 43.05  ? 272 ASN C CA  1 
ATOM   5772  C C   . ASN C 1 70  ? -35.008 29.231  39.130 1.00 41.03  ? 272 ASN C C   1 
ATOM   5773  O O   . ASN C 1 70  ? -34.151 29.989  39.595 1.00 41.01  ? 272 ASN C O   1 
ATOM   5774  C CB  . ASN C 1 70  ? -33.775 28.740  37.002 1.00 41.89  ? 272 ASN C CB  1 
ATOM   5775  C CG  . ASN C 1 70  ? -33.043 27.677  36.215 1.00 42.21  ? 272 ASN C CG  1 
ATOM   5776  O OD1 . ASN C 1 70  ? -32.768 26.596  36.730 1.00 43.54  ? 272 ASN C OD1 1 
ATOM   5777  N ND2 . ASN C 1 70  ? -32.730 27.973  34.961 1.00 43.16  ? 272 ASN C ND2 1 
ATOM   5778  N N   . ALA C 1 71  ? -36.296 29.332  39.455 1.00 49.38  ? 273 ALA C N   1 
ATOM   5779  C CA  . ALA C 1 71  ? -36.763 30.380  40.354 1.00 46.60  ? 273 ALA C CA  1 
ATOM   5780  C C   . ALA C 1 71  ? -36.139 30.242  41.737 1.00 45.17  ? 273 ALA C C   1 
ATOM   5781  O O   . ALA C 1 71  ? -35.955 29.134  42.246 1.00 45.53  ? 273 ALA C O   1 
ATOM   5782  C CB  . ALA C 1 71  ? -38.286 30.346  40.461 1.00 45.45  ? 273 ALA C CB  1 
ATOM   5783  N N   . TYR C 1 72  ? -35.805 31.380  42.344 1.00 47.89  ? 274 TYR C N   1 
ATOM   5784  C CA  . TYR C 1 72  ? -35.231 31.380  43.682 1.00 45.79  ? 274 TYR C CA  1 
ATOM   5785  C C   . TYR C 1 72  ? -35.559 32.696  44.369 1.00 44.25  ? 274 TYR C C   1 
ATOM   5786  O O   . TYR C 1 72  ? -35.826 33.708  43.717 1.00 43.72  ? 274 TYR C O   1 
ATOM   5787  C CB  . TYR C 1 72  ? -33.716 31.151  43.647 1.00 45.87  ? 274 TYR C CB  1 
ATOM   5788  C CG  . TYR C 1 72  ? -32.907 32.261  43.010 1.00 46.36  ? 274 TYR C CG  1 
ATOM   5789  C CD1 . TYR C 1 72  ? -32.388 33.294  43.776 1.00 47.29  ? 274 TYR C CD1 1 
ATOM   5790  C CD2 . TYR C 1 72  ? -32.651 32.269  41.647 1.00 46.69  ? 274 TYR C CD2 1 
ATOM   5791  C CE1 . TYR C 1 72  ? -31.644 34.300  43.207 1.00 47.85  ? 274 TYR C CE1 1 
ATOM   5792  C CE2 . TYR C 1 72  ? -31.905 33.271  41.069 1.00 47.30  ? 274 TYR C CE2 1 
ATOM   5793  C CZ  . TYR C 1 72  ? -31.405 34.285  41.854 1.00 47.92  ? 274 TYR C CZ  1 
ATOM   5794  O OH  . TYR C 1 72  ? -30.662 35.291  41.284 1.00 48.18  ? 274 TYR C OH  1 
ATOM   5795  N N   . PHE C 1 73  ? -35.544 32.663  45.699 1.00 40.37  ? 275 PHE C N   1 
ATOM   5796  C CA  . PHE C 1 73  ? -35.712 33.850  46.525 1.00 39.68  ? 275 PHE C CA  1 
ATOM   5797  C C   . PHE C 1 73  ? -34.834 33.708  47.757 1.00 39.99  ? 275 PHE C C   1 
ATOM   5798  O O   . PHE C 1 73  ? -34.807 32.642  48.379 1.00 40.50  ? 275 PHE C O   1 
ATOM   5799  C CB  . PHE C 1 73  ? -37.167 34.039  46.950 1.00 40.93  ? 275 PHE C CB  1 
ATOM   5800  C CG  . PHE C 1 73  ? -37.387 35.218  47.846 1.00 40.73  ? 275 PHE C CG  1 
ATOM   5801  C CD1 . PHE C 1 73  ? -37.621 36.468  47.314 1.00 41.01  ? 275 PHE C CD1 1 
ATOM   5802  C CD2 . PHE C 1 73  ? -37.322 35.084  49.219 1.00 41.00  ? 275 PHE C CD2 1 
ATOM   5803  C CE1 . PHE C 1 73  ? -37.821 37.550  48.135 1.00 40.75  ? 275 PHE C CE1 1 
ATOM   5804  C CE2 . PHE C 1 73  ? -37.512 36.164  50.045 1.00 41.34  ? 275 PHE C CE2 1 
ATOM   5805  C CZ  . PHE C 1 73  ? -37.762 37.401  49.503 1.00 41.60  ? 275 PHE C CZ  1 
ATOM   5806  N N   . GLY C 1 74  ? -34.149 34.780  48.127 1.00 38.93  ? 276 GLY C N   1 
ATOM   5807  C CA  . GLY C 1 74  ? -33.288 34.711  49.287 1.00 38.23  ? 276 GLY C CA  1 
ATOM   5808  C C   . GLY C 1 74  ? -32.638 36.041  49.581 1.00 38.73  ? 276 GLY C C   1 
ATOM   5809  O O   . GLY C 1 74  ? -33.076 37.089  49.108 1.00 39.72  ? 276 GLY C O   1 
ATOM   5810  N N   . TYR C 1 75  ? -31.574 35.979  50.373 1.00 36.55  ? 277 TYR C N   1 
ATOM   5811  C CA  . TYR C 1 75  ? -30.884 37.166  50.845 1.00 36.12  ? 277 TYR C CA  1 
ATOM   5812  C C   . TYR C 1 75  ? -29.381 36.958  50.774 1.00 36.43  ? 277 TYR C C   1 
ATOM   5813  O O   . TYR C 1 75  ? -28.886 35.852  51.005 1.00 36.83  ? 277 TYR C O   1 
ATOM   5814  C CB  . TYR C 1 75  ? -31.293 37.504  52.284 1.00 35.32  ? 277 TYR C CB  1 
ATOM   5815  C CG  . TYR C 1 75  ? -32.751 37.865  52.427 1.00 35.74  ? 277 TYR C CG  1 
ATOM   5816  C CD1 . TYR C 1 75  ? -33.181 39.171  52.253 1.00 36.96  ? 277 TYR C CD1 1 
ATOM   5817  C CD2 . TYR C 1 75  ? -33.698 36.899  52.725 1.00 34.92  ? 277 TYR C CD2 1 
ATOM   5818  C CE1 . TYR C 1 75  ? -34.511 39.504  52.379 1.00 38.94  ? 277 TYR C CE1 1 
ATOM   5819  C CE2 . TYR C 1 75  ? -35.029 37.222  52.852 1.00 36.48  ? 277 TYR C CE2 1 
ATOM   5820  C CZ  . TYR C 1 75  ? -35.430 38.526  52.680 1.00 38.52  ? 277 TYR C CZ  1 
ATOM   5821  O OH  . TYR C 1 75  ? -36.759 38.850  52.806 1.00 40.58  ? 277 TYR C OH  1 
ATOM   5822  N N   . SER C 1 76  ? -28.663 38.023  50.440 1.00 34.69  ? 278 SER C N   1 
ATOM   5823  C CA  . SER C 1 76  ? -27.213 38.058  50.542 1.00 35.52  ? 278 SER C CA  1 
ATOM   5824  C C   . SER C 1 76  ? -26.833 38.831  51.797 1.00 35.94  ? 278 SER C C   1 
ATOM   5825  O O   . SER C 1 76  ? -27.521 39.780  52.185 1.00 36.26  ? 278 SER C O   1 
ATOM   5826  C CB  . SER C 1 76  ? -26.583 38.699  49.306 1.00 35.30  ? 278 SER C CB  1 
ATOM   5827  O OG  . SER C 1 76  ? -26.949 40.059  49.189 1.00 36.99  ? 278 SER C OG  1 
ATOM   5828  N N   . THR C 1 77  ? -25.755 38.409  52.440 1.00 33.13  ? 279 THR C N   1 
ATOM   5829  C CA  . THR C 1 77  ? -25.329 38.961  53.713 1.00 32.82  ? 279 THR C CA  1 
ATOM   5830  C C   . THR C 1 77  ? -23.913 39.511  53.607 1.00 32.93  ? 279 THR C C   1 
ATOM   5831  O O   . THR C 1 77  ? -23.158 39.138  52.702 1.00 34.28  ? 279 THR C O   1 
ATOM   5832  C CB  . THR C 1 77  ? -25.379 37.888  54.810 1.00 36.80  ? 279 THR C CB  1 
ATOM   5833  O OG1 . THR C 1 77  ? -24.451 36.842  54.500 1.00 36.76  ? 279 THR C OG1 1 
ATOM   5834  C CG2 . THR C 1 77  ? -26.769 37.287  54.901 1.00 34.28  ? 279 THR C CG2 1 
ATOM   5835  N N   . PRO C 1 78  ? -23.526 40.423  54.502 1.00 35.08  ? 280 PRO C N   1 
ATOM   5836  C CA  . PRO C 1 78  ? -22.112 40.822  54.581 1.00 34.92  ? 280 PRO C CA  1 
ATOM   5837  C C   . PRO C 1 78  ? -21.192 39.749  55.149 1.00 35.10  ? 280 PRO C C   1 
ATOM   5838  O O   . PRO C 1 78  ? -19.973 39.853  54.967 1.00 36.90  ? 280 PRO C O   1 
ATOM   5839  C CB  . PRO C 1 78  ? -22.151 42.058  55.489 1.00 35.83  ? 280 PRO C CB  1 
ATOM   5840  C CG  . PRO C 1 78  ? -23.380 41.880  56.306 1.00 35.55  ? 280 PRO C CG  1 
ATOM   5841  C CD  . PRO C 1 78  ? -24.374 41.246  55.379 1.00 35.92  ? 280 PRO C CD  1 
ATOM   5842  N N   . TRP C 1 79  ? -21.730 38.765  55.855 1.00 32.27  ? 281 TRP C N   1 
ATOM   5843  C CA  . TRP C 1 79  ? -20.897 37.732  56.462 1.00 31.73  ? 281 TRP C CA  1 
ATOM   5844  C C   . TRP C 1 79  ? -20.229 36.800  55.470 1.00 32.11  ? 281 TRP C C   1 
ATOM   5845  O O   . TRP C 1 79  ? -20.630 36.689  54.318 1.00 32.87  ? 281 TRP C O   1 
ATOM   5846  C CB  . TRP C 1 79  ? -21.705 36.896  57.449 1.00 33.76  ? 281 TRP C CB  1 
ATOM   5847  C CG  . TRP C 1 79  ? -22.206 37.647  58.623 1.00 34.70  ? 281 TRP C CG  1 
ATOM   5848  C CD1 . TRP C 1 79  ? -23.252 38.515  58.650 1.00 35.43  ? 281 TRP C CD1 1 
ATOM   5849  C CD2 . TRP C 1 79  ? -21.697 37.587  59.957 1.00 35.44  ? 281 TRP C CD2 1 
ATOM   5850  N NE1 . TRP C 1 79  ? -23.421 39.008  59.916 1.00 35.98  ? 281 TRP C NE1 1 
ATOM   5851  C CE2 . TRP C 1 79  ? -22.478 38.452  60.738 1.00 35.11  ? 281 TRP C CE2 1 
ATOM   5852  C CE3 . TRP C 1 79  ? -20.655 36.889  60.565 1.00 36.12  ? 281 TRP C CE3 1 
ATOM   5853  C CZ2 . TRP C 1 79  ? -22.248 38.640  62.094 1.00 35.07  ? 281 TRP C CZ2 1 
ATOM   5854  C CZ3 . TRP C 1 79  ? -20.429 37.076  61.910 1.00 36.72  ? 281 TRP C CZ3 1 
ATOM   5855  C CH2 . TRP C 1 79  ? -21.220 37.943  62.659 1.00 36.88  ? 281 TRP C CH2 1 
ATOM   5856  N N   . GLY C 1 80  ? -19.204 36.119  55.957 1.00 29.81  ? 282 GLY C N   1 
ATOM   5857  C CA  . GLY C 1 80  ? -18.432 35.161  55.190 1.00 30.00  ? 282 GLY C CA  1 
ATOM   5858  C C   . GLY C 1 80  ? -18.273 33.921  56.040 1.00 30.67  ? 282 GLY C C   1 
ATOM   5859  O O   . GLY C 1 80  ? -18.371 33.989  57.262 1.00 30.17  ? 282 GLY C O   1 
ATOM   5860  N N   . TYR C 1 81  ? -18.041 32.778  55.411 1.00 29.40  ? 283 TYR C N   1 
ATOM   5861  C CA  . TYR C 1 81  ? -17.906 31.537  56.162 1.00 29.74  ? 283 TYR C CA  1 
ATOM   5862  C C   . TYR C 1 81  ? -16.708 30.715  55.721 1.00 31.00  ? 283 TYR C C   1 
ATOM   5863  O O   . TYR C 1 81  ? -16.245 30.838  54.594 1.00 31.15  ? 283 TYR C O   1 
ATOM   5864  C CB  . TYR C 1 81  ? -19.182 30.707  56.041 1.00 27.59  ? 283 TYR C CB  1 
ATOM   5865  C CG  . TYR C 1 81  ? -19.471 30.234  54.641 1.00 28.58  ? 283 TYR C CG  1 
ATOM   5866  C CD1 . TYR C 1 81  ? -19.077 28.978  54.222 1.00 29.25  ? 283 TYR C CD1 1 
ATOM   5867  C CD2 . TYR C 1 81  ? -20.137 31.042  53.742 1.00 29.12  ? 283 TYR C CD2 1 
ATOM   5868  C CE1 . TYR C 1 81  ? -19.337 28.539  52.948 1.00 30.58  ? 283 TYR C CE1 1 
ATOM   5869  C CE2 . TYR C 1 81  ? -20.400 30.611  52.461 1.00 30.30  ? 283 TYR C CE2 1 
ATOM   5870  C CZ  . TYR C 1 81  ? -19.996 29.358  52.073 1.00 30.72  ? 283 TYR C CZ  1 
ATOM   5871  O OH  . TYR C 1 81  ? -20.257 28.919  50.801 1.00 30.21  ? 283 TYR C OH  1 
ATOM   5872  N N   . PHE C 1 82  ? -16.215 29.868  56.615 1.00 27.46  ? 284 PHE C N   1 
ATOM   5873  C CA  . PHE C 1 82  ? -15.069 29.034  56.312 1.00 28.91  ? 284 PHE C CA  1 
ATOM   5874  C C   . PHE C 1 82  ? -15.551 27.641  55.988 1.00 31.92  ? 284 PHE C C   1 
ATOM   5875  O O   . PHE C 1 82  ? -16.290 27.052  56.754 1.00 33.07  ? 284 PHE C O   1 
ATOM   5876  C CB  . PHE C 1 82  ? -14.118 28.985  57.501 1.00 29.92  ? 284 PHE C CB  1 
ATOM   5877  C CG  . PHE C 1 82  ? -13.366 30.262  57.729 1.00 30.48  ? 284 PHE C CG  1 
ATOM   5878  C CD1 . PHE C 1 82  ? -12.225 30.542  57.006 1.00 29.81  ? 284 PHE C CD1 1 
ATOM   5879  C CD2 . PHE C 1 82  ? -13.800 31.176  58.667 1.00 31.05  ? 284 PHE C CD2 1 
ATOM   5880  C CE1 . PHE C 1 82  ? -11.529 31.713  57.211 1.00 30.55  ? 284 PHE C CE1 1 
ATOM   5881  C CE2 . PHE C 1 82  ? -13.110 32.350  58.879 1.00 31.33  ? 284 PHE C CE2 1 
ATOM   5882  C CZ  . PHE C 1 82  ? -11.971 32.618  58.151 1.00 31.33  ? 284 PHE C CZ  1 
ATOM   5883  N N   . ASP C 1 83  ? -15.130 27.117  54.844 1.00 33.02  ? 285 ASP C N   1 
ATOM   5884  C CA  . ASP C 1 83  ? -15.560 25.793  54.420 1.00 34.69  ? 285 ASP C CA  1 
ATOM   5885  C C   . ASP C 1 83  ? -14.422 24.804  54.160 1.00 32.21  ? 285 ASP C C   1 
ATOM   5886  O O   . ASP C 1 83  ? -13.505 25.086  53.393 1.00 32.76  ? 285 ASP C O   1 
ATOM   5887  C CB  . ASP C 1 83  ? -16.387 25.937  53.145 1.00 31.48  ? 285 ASP C CB  1 
ATOM   5888  C CG  . ASP C 1 83  ? -17.517 24.949  53.073 1.00 37.84  ? 285 ASP C CG  1 
ATOM   5889  O OD1 . ASP C 1 83  ? -18.184 24.743  54.107 1.00 42.30  ? 285 ASP C OD1 1 
ATOM   5890  O OD2 . ASP C 1 83  ? -17.746 24.390  51.982 1.00 41.23  ? 285 ASP C OD2 1 
ATOM   5891  N N   . PHE C 1 84  ? -14.487 23.648  54.813 1.00 29.60  ? 286 PHE C N   1 
ATOM   5892  C CA  . PHE C 1 84  ? -13.512 22.581  54.616 1.00 26.99  ? 286 PHE C CA  1 
ATOM   5893  C C   . PHE C 1 84  ? -14.192 21.249  54.314 1.00 25.05  ? 286 PHE C C   1 
ATOM   5894  O O   . PHE C 1 84  ? -13.668 20.191  54.639 1.00 24.58  ? 286 PHE C O   1 
ATOM   5895  C CB  . PHE C 1 84  ? -12.535 22.463  55.787 1.00 27.92  ? 286 PHE C CB  1 
ATOM   5896  C CG  . PHE C 1 84  ? -13.141 22.735  57.129 1.00 28.42  ? 286 PHE C CG  1 
ATOM   5897  C CD1 . PHE C 1 84  ? -13.570 21.698  57.931 1.00 28.95  ? 286 PHE C CD1 1 
ATOM   5898  C CD2 . PHE C 1 84  ? -13.252 24.027  57.602 1.00 28.67  ? 286 PHE C CD2 1 
ATOM   5899  C CE1 . PHE C 1 84  ? -14.116 21.941  59.174 1.00 28.74  ? 286 PHE C CE1 1 
ATOM   5900  C CE2 . PHE C 1 84  ? -13.800 24.280  58.844 1.00 29.45  ? 286 PHE C CE2 1 
ATOM   5901  C CZ  . PHE C 1 84  ? -14.232 23.236  59.632 1.00 28.82  ? 286 PHE C CZ  1 
ATOM   5902  N N   . ASN C 1 85  ? -15.365 21.307  53.695 1.00 22.06  ? 287 ASN C N   1 
ATOM   5903  C CA  . ASN C 1 85  ? -16.141 20.106  53.391 1.00 20.91  ? 287 ASN C CA  1 
ATOM   5904  C C   . ASN C 1 85  ? -15.489 19.093  52.434 1.00 20.63  ? 287 ASN C C   1 
ATOM   5905  O O   . ASN C 1 85  ? -15.659 17.897  52.606 1.00 21.43  ? 287 ASN C O   1 
ATOM   5906  C CB  . ASN C 1 85  ? -17.562 20.462  52.951 1.00 21.03  ? 287 ASN C CB  1 
ATOM   5907  C CG  . ASN C 1 85  ? -18.574 19.406  53.346 1.00 21.82  ? 287 ASN C CG  1 
ATOM   5908  O OD1 . ASN C 1 85  ? -18.215 18.360  53.864 1.00 20.40  ? 287 ASN C OD1 1 
ATOM   5909  N ND2 . ASN C 1 85  ? -19.843 19.675  53.097 1.00 24.27  ? 287 ASN C ND2 1 
ATOM   5910  N N   . ARG C 1 86  ? -14.771 19.549  51.419 1.00 18.59  ? 288 ARG C N   1 
ATOM   5911  C CA  . ARG C 1 86  ? -14.126 18.622  50.485 1.00 18.66  ? 288 ARG C CA  1 
ATOM   5912  C C   . ARG C 1 86  ? -13.040 17.786  51.152 1.00 18.91  ? 288 ARG C C   1 
ATOM   5913  O O   . ARG C 1 86  ? -12.409 18.221  52.096 1.00 19.01  ? 288 ARG C O   1 
ATOM   5914  C CB  . ARG C 1 86  ? -13.540 19.373  49.296 1.00 18.26  ? 288 ARG C CB  1 
ATOM   5915  C CG  . ARG C 1 86  ? -14.503 20.361  48.678 1.00 18.77  ? 288 ARG C CG  1 
ATOM   5916  C CD  . ARG C 1 86  ? -13.859 21.085  47.520 1.00 19.65  ? 288 ARG C CD  1 
ATOM   5917  N NE  . ARG C 1 86  ? -13.625 20.184  46.407 1.00 20.97  ? 288 ARG C NE  1 
ATOM   5918  C CZ  . ARG C 1 86  ? -13.160 20.570  45.231 1.00 21.84  ? 288 ARG C CZ  1 
ATOM   5919  N NH1 . ARG C 1 86  ? -12.877 21.843  45.018 1.00 21.42  ? 288 ARG C NH1 1 
ATOM   5920  N NH2 . ARG C 1 86  ? -12.982 19.683  44.270 1.00 19.92  ? 288 ARG C NH2 1 
ATOM   5921  N N   . PHE C 1 87  ? -12.847 16.565  50.683 1.00 15.51  ? 289 PHE C N   1 
ATOM   5922  C CA  . PHE C 1 87  ? -11.832 15.697  51.260 1.00 16.23  ? 289 PHE C CA  1 
ATOM   5923  C C   . PHE C 1 87  ? -10.398 16.177  51.100 1.00 17.54  ? 289 PHE C C   1 
ATOM   5924  O O   . PHE C 1 87  ? -9.605  16.013  52.013 1.00 17.13  ? 289 PHE C O   1 
ATOM   5925  C CB  . PHE C 1 87  ? -11.981 14.253  50.782 1.00 16.35  ? 289 PHE C CB  1 
ATOM   5926  C CG  . PHE C 1 87  ? -12.892 13.431  51.638 1.00 16.66  ? 289 PHE C CG  1 
ATOM   5927  C CD1 . PHE C 1 87  ? -12.540 13.112  52.935 1.00 15.72  ? 289 PHE C CD1 1 
ATOM   5928  C CD2 . PHE C 1 87  ? -14.098 12.974  51.147 1.00 16.26  ? 289 PHE C CD2 1 
ATOM   5929  C CE1 . PHE C 1 87  ? -13.377 12.358  53.727 1.00 16.13  ? 289 PHE C CE1 1 
ATOM   5930  C CE2 . PHE C 1 87  ? -14.940 12.219  51.933 1.00 15.75  ? 289 PHE C CE2 1 
ATOM   5931  C CZ  . PHE C 1 87  ? -14.580 11.912  53.224 1.00 15.45  ? 289 PHE C CZ  1 
ATOM   5932  N N   . HIS C 1 88  ? -10.046 16.751  49.953 1.00 17.07  ? 290 HIS C N   1 
ATOM   5933  C CA  . HIS C 1 88  ? -8.662  17.195  49.760 1.00 18.80  ? 290 HIS C CA  1 
ATOM   5934  C C   . HIS C 1 88  ? -8.183  18.301  50.699 1.00 19.89  ? 290 HIS C C   1 
ATOM   5935  O O   . HIS C 1 88  ? -6.999  18.566  50.797 1.00 21.36  ? 290 HIS C O   1 
ATOM   5936  C CB  . HIS C 1 88  ? -8.297  17.441  48.296 1.00 18.31  ? 290 HIS C CB  1 
ATOM   5937  C CG  . HIS C 1 88  ? -9.092  18.509  47.634 1.00 19.52  ? 290 HIS C CG  1 
ATOM   5938  N ND1 . HIS C 1 88  ? -9.525  19.634  48.296 1.00 21.47  ? 290 HIS C ND1 1 
ATOM   5939  C CD2 . HIS C 1 88  ? -9.485  18.651  46.349 1.00 19.18  ? 290 HIS C CD2 1 
ATOM   5940  C CE1 . HIS C 1 88  ? -10.177 20.412  47.454 1.00 20.73  ? 290 HIS C CE1 1 
ATOM   5941  N NE2 . HIS C 1 88  ? -10.168 19.837  46.266 1.00 19.96  ? 290 HIS C NE2 1 
ATOM   5942  N N   . CYS C 1 89  ? -9.102  18.961  51.376 1.00 19.32  ? 291 CYS C N   1 
ATOM   5943  C CA  . CYS C 1 89  ? -8.709  19.927  52.389 1.00 21.21  ? 291 CYS C CA  1 
ATOM   5944  C C   . CYS C 1 89  ? -7.843  19.270  53.455 1.00 20.16  ? 291 CYS C C   1 
ATOM   5945  O O   . CYS C 1 89  ? -6.819  19.826  53.865 1.00 19.53  ? 291 CYS C O   1 
ATOM   5946  C CB  . CYS C 1 89  ? -9.953  20.550  53.018 1.00 24.12  ? 291 CYS C CB  1 
ATOM   5947  S SG  . CYS C 1 89  ? -11.009 21.431  51.851 1.00 32.95  ? 291 CYS C SG  1 
ATOM   5948  N N   . HIS C 1 90  ? -8.250  18.090  53.924 1.00 21.03  ? 292 HIS C N   1 
ATOM   5949  C CA  . HIS C 1 90  ? -7.601  17.422  55.041 1.00 19.96  ? 292 HIS C CA  1 
ATOM   5950  C C   . HIS C 1 90  ? -6.576  16.370  54.638 1.00 19.69  ? 292 HIS C C   1 
ATOM   5951  O O   . HIS C 1 90  ? -5.825  15.906  55.501 1.00 21.05  ? 292 HIS C O   1 
ATOM   5952  C CB  . HIS C 1 90  ? -8.672  16.771  55.918 1.00 22.33  ? 292 HIS C CB  1 
ATOM   5953  C CG  . HIS C 1 90  ? -9.779  17.705  56.283 1.00 23.38  ? 292 HIS C CG  1 
ATOM   5954  N ND1 . HIS C 1 90  ? -9.612  18.754  57.159 1.00 24.85  ? 292 HIS C ND1 1 
ATOM   5955  C CD2 . HIS C 1 90  ? -11.058 17.780  55.847 1.00 23.68  ? 292 HIS C CD2 1 
ATOM   5956  C CE1 . HIS C 1 90  ? -10.747 19.421  57.267 1.00 25.40  ? 292 HIS C CE1 1 
ATOM   5957  N NE2 . HIS C 1 90  ? -11.641 18.848  56.483 1.00 24.56  ? 292 HIS C NE2 1 
ATOM   5958  N N   . PHE C 1 91  ? -6.514  15.983  53.368 1.00 17.95  ? 293 PHE C N   1 
ATOM   5959  C CA  . PHE C 1 91  ? -5.673  14.872  52.941 1.00 16.98  ? 293 PHE C CA  1 
ATOM   5960  C C   . PHE C 1 91  ? -4.803  15.287  51.769 1.00 17.42  ? 293 PHE C C   1 
ATOM   5961  O O   . PHE C 1 91  ? -5.289  15.896  50.813 1.00 19.03  ? 293 PHE C O   1 
ATOM   5962  C CB  . PHE C 1 91  ? -6.510  13.654  52.540 1.00 15.54  ? 293 PHE C CB  1 
ATOM   5963  C CG  . PHE C 1 91  ? -7.211  12.989  53.685 1.00 15.27  ? 293 PHE C CG  1 
ATOM   5964  C CD1 . PHE C 1 91  ? -6.564  12.034  54.449 1.00 15.37  ? 293 PHE C CD1 1 
ATOM   5965  C CD2 . PHE C 1 91  ? -8.517  13.312  53.994 1.00 15.75  ? 293 PHE C CD2 1 
ATOM   5966  C CE1 . PHE C 1 91  ? -7.210  11.419  55.501 1.00 15.61  ? 293 PHE C CE1 1 
ATOM   5967  C CE2 . PHE C 1 91  ? -9.164  12.702  55.043 1.00 16.30  ? 293 PHE C CE2 1 
ATOM   5968  C CZ  . PHE C 1 91  ? -8.510  11.755  55.796 1.00 16.01  ? 293 PHE C CZ  1 
ATOM   5969  N N   . SER C 1 92  ? -3.524  14.941  51.844 1.00 13.98  ? 294 SER C N   1 
ATOM   5970  C CA  . SER C 1 92  ? -2.643  15.054  50.702 1.00 13.35  ? 294 SER C CA  1 
ATOM   5971  C C   . SER C 1 92  ? -2.874  13.880  49.757 1.00 12.61  ? 294 SER C C   1 
ATOM   5972  O O   . SER C 1 92  ? -3.498  12.886  50.131 1.00 11.43  ? 294 SER C O   1 
ATOM   5973  C CB  . SER C 1 92  ? -1.188  15.090  51.161 1.00 13.69  ? 294 SER C CB  1 
ATOM   5974  O OG  . SER C 1 92  ? -0.822  13.896  51.828 1.00 14.91  ? 294 SER C OG  1 
ATOM   5975  N N   . PRO C 1 93  ? -2.401  13.978  48.513 1.00 10.39  ? 295 PRO C N   1 
ATOM   5976  C CA  . PRO C 1 93  ? -2.453  12.802  47.635 1.00 10.47  ? 295 PRO C CA  1 
ATOM   5977  C C   . PRO C 1 93  ? -1.718  11.607  48.210 1.00 11.25  ? 295 PRO C C   1 
ATOM   5978  O O   . PRO C 1 93  ? -2.048  10.462  47.890 1.00 10.56  ? 295 PRO C O   1 
ATOM   5979  C CB  . PRO C 1 93  ? -1.799  13.312  46.346 1.00 10.40  ? 295 PRO C CB  1 
ATOM   5980  C CG  . PRO C 1 93  ? -2.025  14.759  46.362 1.00 11.63  ? 295 PRO C CG  1 
ATOM   5981  C CD  . PRO C 1 93  ? -1.937  15.171  47.791 1.00 11.17  ? 295 PRO C CD  1 
ATOM   5982  N N   . ARG C 1 94  ? -0.717  11.846  49.054 1.00 11.03  ? 296 ARG C N   1 
ATOM   5983  C CA  . ARG C 1 94  ? -0.022  10.743  49.701 1.00 12.94  ? 296 ARG C CA  1 
ATOM   5984  C C   . ARG C 1 94  ? -0.827  10.204  50.874 1.00 12.61  ? 296 ARG C C   1 
ATOM   5985  O O   . ARG C 1 94  ? -0.922  8.987   51.064 1.00 12.00  ? 296 ARG C O   1 
ATOM   5986  C CB  . ARG C 1 94  ? 1.353   11.198  50.171 1.00 8.94   ? 296 ARG C CB  1 
ATOM   5987  C CG  . ARG C 1 94  ? 2.161   10.117  50.850 1.00 12.34  ? 296 ARG C CG  1 
ATOM   5988  C CD  . ARG C 1 94  ? 2.618   9.069   49.860 1.00 16.51  ? 296 ARG C CD  1 
ATOM   5989  N NE  . ARG C 1 94  ? 3.342   7.991   50.521 1.00 22.50  ? 296 ARG C NE  1 
ATOM   5990  C CZ  . ARG C 1 94  ? 2.785   6.860   50.933 1.00 24.61  ? 296 ARG C CZ  1 
ATOM   5991  N NH1 . ARG C 1 94  ? 1.498   6.640   50.723 1.00 24.18  ? 296 ARG C NH1 1 
ATOM   5992  N NH2 . ARG C 1 94  ? 3.521   5.936   51.529 1.00 24.40  ? 296 ARG C NH2 1 
ATOM   5993  N N   . ASP C 1 95  ? -1.403  11.099  51.680 1.00 13.64  ? 297 ASP C N   1 
ATOM   5994  C CA  . ASP C 1 95  ? -2.224  10.665  52.805 1.00 14.45  ? 297 ASP C CA  1 
ATOM   5995  C C   . ASP C 1 95  ? -3.472  9.945   52.330 1.00 12.63  ? 297 ASP C C   1 
ATOM   5996  O O   . ASP C 1 95  ? -3.955  9.022   52.992 1.00 12.24  ? 297 ASP C O   1 
ATOM   5997  C CB  . ASP C 1 95  ? -2.610  11.862  53.668 1.00 15.91  ? 297 ASP C CB  1 
ATOM   5998  C CG  . ASP C 1 95  ? -1.456  12.395  54.470 1.00 21.51  ? 297 ASP C CG  1 
ATOM   5999  O OD1 . ASP C 1 95  ? -0.472  11.654  54.657 1.00 23.15  ? 297 ASP C OD1 1 
ATOM   6000  O OD2 . ASP C 1 95  ? -1.528  13.561  54.906 1.00 24.64  ? 297 ASP C OD2 1 
ATOM   6001  N N   . TRP C 1 96  ? -4.014  10.357  51.187 1.00 12.55  ? 298 TRP C N   1 
ATOM   6002  C CA  . TRP C 1 96  ? -5.213  9.711   50.672 1.00 11.67  ? 298 TRP C CA  1 
ATOM   6003  C C   . TRP C 1 96  ? -4.884  8.331   50.117 1.00 11.79  ? 298 TRP C C   1 
ATOM   6004  O O   . TRP C 1 96  ? -5.677  7.395   50.251 1.00 11.48  ? 298 TRP C O   1 
ATOM   6005  C CB  . TRP C 1 96  ? -5.855  10.594  49.605 1.00 12.23  ? 298 TRP C CB  1 
ATOM   6006  C CG  . TRP C 1 96  ? -7.153  10.078  49.076 1.00 11.30  ? 298 TRP C CG  1 
ATOM   6007  C CD1 . TRP C 1 96  ? -7.348  9.399   47.917 1.00 10.89  ? 298 TRP C CD1 1 
ATOM   6008  C CD2 . TRP C 1 96  ? -8.444  10.232  49.673 1.00 12.09  ? 298 TRP C CD2 1 
ATOM   6009  N NE1 . TRP C 1 96  ? -8.676  9.103   47.759 1.00 11.79  ? 298 TRP C NE1 1 
ATOM   6010  C CE2 . TRP C 1 96  ? -9.371  9.605   48.825 1.00 12.01  ? 298 TRP C CE2 1 
ATOM   6011  C CE3 . TRP C 1 96  ? -8.904  10.834  50.847 1.00 12.16  ? 298 TRP C CE3 1 
ATOM   6012  C CZ2 . TRP C 1 96  ? -10.728 9.561   49.109 1.00 11.71  ? 298 TRP C CZ2 1 
ATOM   6013  C CZ3 . TRP C 1 96  ? -10.249 10.789  51.127 1.00 12.17  ? 298 TRP C CZ3 1 
ATOM   6014  C CH2 . TRP C 1 96  ? -11.147 10.158  50.262 1.00 11.97  ? 298 TRP C CH2 1 
ATOM   6015  N N   . GLN C 1 97  ? -3.713  8.187   49.499 1.00 9.32   ? 299 GLN C N   1 
ATOM   6016  C CA  . GLN C 1 97  ? -3.268  6.881   49.026 1.00 9.89   ? 299 GLN C CA  1 
ATOM   6017  C C   . GLN C 1 97  ? -2.981  5.960   50.198 1.00 11.39  ? 299 GLN C C   1 
ATOM   6018  O O   . GLN C 1 97  ? -3.273  4.762   50.155 1.00 11.66  ? 299 GLN C O   1 
ATOM   6019  C CB  . GLN C 1 97  ? -2.012  7.038   48.182 1.00 9.02   ? 299 GLN C CB  1 
ATOM   6020  C CG  . GLN C 1 97  ? -1.633  5.813   47.409 1.00 8.88   ? 299 GLN C CG  1 
ATOM   6021  C CD  . GLN C 1 97  ? -0.329  6.001   46.696 1.00 10.44  ? 299 GLN C CD  1 
ATOM   6022  O OE1 . GLN C 1 97  ? 0.373   6.974   46.931 1.00 11.87  ? 299 GLN C OE1 1 
ATOM   6023  N NE2 . GLN C 1 97  ? -0.031  5.117   45.765 1.00 10.39  ? 299 GLN C NE2 1 
ATOM   6024  N N   . ARG C 1 98  ? -2.379  6.510   51.251 1.00 12.61  ? 300 ARG C N   1 
ATOM   6025  C CA  . ARG C 1 98  ? -2.110  5.735   52.451 1.00 15.16  ? 300 ARG C CA  1 
ATOM   6026  C C   . ARG C 1 98  ? -3.405  5.293   53.116 1.00 13.74  ? 300 ARG C C   1 
ATOM   6027  O O   . ARG C 1 98  ? -3.443  4.247   53.772 1.00 13.73  ? 300 ARG C O   1 
ATOM   6028  C CB  . ARG C 1 98  ? -1.259  6.570   53.409 1.00 7.02   ? 300 ARG C CB  1 
ATOM   6029  C CG  . ARG C 1 98  ? -0.747  5.829   54.613 1.00 15.48  ? 300 ARG C CG  1 
ATOM   6030  C CD  . ARG C 1 98  ? 0.173   6.690   55.468 1.00 24.00  ? 300 ARG C CD  1 
ATOM   6031  N NE  . ARG C 1 98  ? 1.398   7.113   54.791 1.00 33.93  ? 300 ARG C NE  1 
ATOM   6032  C CZ  . ARG C 1 98  ? 1.642   8.358   54.395 1.00 38.14  ? 300 ARG C CZ  1 
ATOM   6033  N NH1 . ARG C 1 98  ? 0.744   9.306   54.602 1.00 38.63  ? 300 ARG C NH1 1 
ATOM   6034  N NH2 . ARG C 1 98  ? 2.783   8.659   53.795 1.00 38.48  ? 300 ARG C NH2 1 
ATOM   6035  N N   . LEU C 1 99  ? -4.473  6.075   52.951 1.00 14.22  ? 301 LEU C N   1 
ATOM   6036  C CA  . LEU C 1 99  ? -5.771  5.723   53.517 1.00 12.77  ? 301 LEU C CA  1 
ATOM   6037  C C   . LEU C 1 99  ? -6.468  4.645   52.700 1.00 13.39  ? 301 LEU C C   1 
ATOM   6038  O O   . LEU C 1 99  ? -6.905  3.625   53.242 1.00 13.54  ? 301 LEU C O   1 
ATOM   6039  C CB  . LEU C 1 99  ? -6.653  6.965   53.590 1.00 13.23  ? 301 LEU C CB  1 
ATOM   6040  C CG  . LEU C 1 99  ? -8.105  6.764   54.019 1.00 13.06  ? 301 LEU C CG  1 
ATOM   6041  C CD1 . LEU C 1 99  ? -8.172  6.349   55.464 1.00 12.40  ? 301 LEU C CD1 1 
ATOM   6042  C CD2 . LEU C 1 99  ? -8.926  8.012   53.768 1.00 13.20  ? 301 LEU C CD2 1 
ATOM   6043  N N   . ILE C 1 100 ? -6.579  4.856   51.388 1.00 12.14  ? 302 ILE C N   1 
ATOM   6044  C CA  . ILE C 1 100 ? -7.454  4.028   50.565 1.00 11.72  ? 302 ILE C CA  1 
ATOM   6045  C C   . ILE C 1 100 ? -6.866  2.659   50.274 1.00 11.38  ? 302 ILE C C   1 
ATOM   6046  O O   . ILE C 1 100 ? -7.615  1.717   49.997 1.00 12.63  ? 302 ILE C O   1 
ATOM   6047  C CB  . ILE C 1 100 ? -7.774  4.738   49.242 1.00 10.52  ? 302 ILE C CB  1 
ATOM   6048  C CG1 . ILE C 1 100 ? -6.490  4.980   48.451 1.00 12.78  ? 302 ILE C CG1 1 
ATOM   6049  C CG2 . ILE C 1 100 ? -8.479  6.045   49.509 1.00 13.15  ? 302 ILE C CG2 1 
ATOM   6050  C CD1 . ILE C 1 100 ? -6.706  5.553   47.093 1.00 16.69  ? 302 ILE C CD1 1 
ATOM   6051  N N   . ASN C 1 101 ? -5.548  2.527   50.308 1.00 11.42  ? 303 ASN C N   1 
ATOM   6052  C CA  . ASN C 1 101 ? -4.912  1.249   50.042 1.00 11.21  ? 303 ASN C CA  1 
ATOM   6053  C C   . ASN C 1 101 ? -4.888  0.327   51.249 1.00 11.71  ? 303 ASN C C   1 
ATOM   6054  O O   . ASN C 1 101 ? -4.856  -0.894  51.074 1.00 12.05  ? 303 ASN C O   1 
ATOM   6055  C CB  . ASN C 1 101 ? -3.489  1.484   49.551 1.00 10.97  ? 303 ASN C CB  1 
ATOM   6056  C CG  . ASN C 1 101 ? -3.443  2.021   48.142 1.00 11.11  ? 303 ASN C CG  1 
ATOM   6057  O OD1 . ASN C 1 101 ? -4.391  1.873   47.378 1.00 10.24  ? 303 ASN C OD1 1 
ATOM   6058  N ND2 . ASN C 1 101 ? -2.326  2.631   47.783 1.00 9.65   ? 303 ASN C ND2 1 
ATOM   6059  N N   . ASN C 1 102 ? -4.832  0.878   52.457 1.00 14.15  ? 304 ASN C N   1 
ATOM   6060  C CA  . ASN C 1 102 ? -4.625  0.087   53.660 1.00 14.62  ? 304 ASN C CA  1 
ATOM   6061  C C   . ASN C 1 102 ? -5.875  -0.176  54.491 1.00 14.98  ? 304 ASN C C   1 
ATOM   6062  O O   . ASN C 1 102 ? -5.784  -0.898  55.487 1.00 15.40  ? 304 ASN C O   1 
ATOM   6063  C CB  . ASN C 1 102 ? -3.571  0.767   54.532 1.00 11.06  ? 304 ASN C CB  1 
ATOM   6064  C CG  . ASN C 1 102 ? -2.220  0.783   53.877 1.00 14.05  ? 304 ASN C CG  1 
ATOM   6065  O OD1 . ASN C 1 102 ? -1.553  -0.243  53.799 1.00 17.48  ? 304 ASN C OD1 1 
ATOM   6066  N ND2 . ASN C 1 102 ? -1.806  1.944   53.395 1.00 14.40  ? 304 ASN C ND2 1 
ATOM   6067  N N   . ASN C 1 103 ? -7.033  0.367   54.129 1.00 17.62  ? 305 ASN C N   1 
ATOM   6068  C CA  . ASN C 1 103 ? -8.163  0.381   55.050 1.00 17.47  ? 305 ASN C CA  1 
ATOM   6069  C C   . ASN C 1 103 ? -9.457  -0.041  54.374 1.00 17.51  ? 305 ASN C C   1 
ATOM   6070  O O   . ASN C 1 103 ? -9.674  0.236   53.192 1.00 17.72  ? 305 ASN C O   1 
ATOM   6071  C CB  . ASN C 1 103 ? -8.347  1.769   55.664 1.00 16.67  ? 305 ASN C CB  1 
ATOM   6072  C CG  . ASN C 1 103 ? -7.254  2.119   56.645 1.00 17.45  ? 305 ASN C CG  1 
ATOM   6073  O OD1 . ASN C 1 103 ? -7.244  1.639   57.774 1.00 20.20  ? 305 ASN C OD1 1 
ATOM   6074  N ND2 . ASN C 1 103 ? -6.330  2.966   56.222 1.00 17.85  ? 305 ASN C ND2 1 
ATOM   6075  N N   . TRP C 1 104 ? -10.313 -0.717  55.144 1.00 18.56  ? 306 TRP C N   1 
ATOM   6076  C CA  . TRP C 1 104 ? -11.675 -1.026  54.727 1.00 19.05  ? 306 TRP C CA  1 
ATOM   6077  C C   . TRP C 1 104 ? -12.680 0.048   55.104 1.00 18.95  ? 306 TRP C C   1 
ATOM   6078  O O   . TRP C 1 104 ? -13.812 0.013   54.612 1.00 20.06  ? 306 TRP C O   1 
ATOM   6079  C CB  . TRP C 1 104 ? -12.124 -2.353  55.338 1.00 17.63  ? 306 TRP C CB  1 
ATOM   6080  C CG  . TRP C 1 104 ? -11.676 -3.549  54.595 1.00 20.65  ? 306 TRP C CG  1 
ATOM   6081  C CD1 . TRP C 1 104 ? -11.171 -3.585  53.334 1.00 21.85  ? 306 TRP C CD1 1 
ATOM   6082  C CD2 . TRP C 1 104 ? -11.663 -4.894  55.073 1.00 22.98  ? 306 TRP C CD2 1 
ATOM   6083  N NE1 . TRP C 1 104 ? -10.871 -4.874  52.983 1.00 22.80  ? 306 TRP C NE1 1 
ATOM   6084  C CE2 . TRP C 1 104 ? -11.154 -5.696  54.040 1.00 23.53  ? 306 TRP C CE2 1 
ATOM   6085  C CE3 . TRP C 1 104 ? -12.035 -5.498  56.277 1.00 22.35  ? 306 TRP C CE3 1 
ATOM   6086  C CZ2 . TRP C 1 104 ? -11.011 -7.070  54.170 1.00 24.01  ? 306 TRP C CZ2 1 
ATOM   6087  C CZ3 . TRP C 1 104 ? -11.890 -6.862  56.404 1.00 22.60  ? 306 TRP C CZ3 1 
ATOM   6088  C CH2 . TRP C 1 104 ? -11.384 -7.634  55.356 1.00 24.18  ? 306 TRP C CH2 1 
ATOM   6089  N N   . GLY C 1 105 ? -12.308 0.992   55.956 1.00 19.93  ? 307 GLY C N   1 
ATOM   6090  C CA  . GLY C 1 105 ? -13.276 1.982   56.384 1.00 19.81  ? 307 GLY C CA  1 
ATOM   6091  C C   . GLY C 1 105 ? -12.633 3.063   57.217 1.00 19.48  ? 307 GLY C C   1 
ATOM   6092  O O   . GLY C 1 105 ? -11.558 2.884   57.793 1.00 18.68  ? 307 GLY C O   1 
ATOM   6093  N N   . PHE C 1 106 ? -13.318 4.201   57.262 1.00 18.11  ? 308 PHE C N   1 
ATOM   6094  C CA  . PHE C 1 106 ? -12.881 5.349   58.041 1.00 19.06  ? 308 PHE C CA  1 
ATOM   6095  C C   . PHE C 1 106 ? -14.092 6.226   58.317 1.00 19.33  ? 308 PHE C C   1 
ATOM   6096  O O   . PHE C 1 106 ? -15.149 6.067   57.704 1.00 19.43  ? 308 PHE C O   1 
ATOM   6097  C CB  . PHE C 1 106 ? -11.771 6.128   57.328 1.00 14.41  ? 308 PHE C CB  1 
ATOM   6098  C CG  . PHE C 1 106 ? -12.156 6.634   55.975 1.00 15.61  ? 308 PHE C CG  1 
ATOM   6099  C CD1 . PHE C 1 106 ? -12.730 7.880   55.825 1.00 16.04  ? 308 PHE C CD1 1 
ATOM   6100  C CD2 . PHE C 1 106 ? -11.947 5.863   54.853 1.00 17.38  ? 308 PHE C CD2 1 
ATOM   6101  C CE1 . PHE C 1 106 ? -13.081 8.344   54.583 1.00 17.37  ? 308 PHE C CE1 1 
ATOM   6102  C CE2 . PHE C 1 106 ? -12.299 6.325   53.612 1.00 18.09  ? 308 PHE C CE2 1 
ATOM   6103  C CZ  . PHE C 1 106 ? -12.869 7.565   53.477 1.00 17.10  ? 308 PHE C CZ  1 
ATOM   6104  N N   . ARG C 1 107 ? -13.916 7.168   59.240 1.00 21.67  ? 309 ARG C N   1 
ATOM   6105  C CA  . ARG C 1 107 ? -14.971 8.096   59.627 1.00 21.96  ? 309 ARG C CA  1 
ATOM   6106  C C   . ARG C 1 107 ? -14.423 9.144   60.585 1.00 21.36  ? 309 ARG C C   1 
ATOM   6107  O O   . ARG C 1 107 ? -13.532 8.851   61.391 1.00 21.92  ? 309 ARG C O   1 
ATOM   6108  C CB  . ARG C 1 107 ? -16.140 7.362   60.281 1.00 19.03  ? 309 ARG C CB  1 
ATOM   6109  C CG  . ARG C 1 107 ? -15.768 6.617   61.541 1.00 20.51  ? 309 ARG C CG  1 
ATOM   6110  C CD  . ARG C 1 107 ? -16.985 6.028   62.200 1.00 23.84  ? 309 ARG C CD  1 
ATOM   6111  N NE  . ARG C 1 107 ? -16.643 5.348   63.442 1.00 28.57  ? 309 ARG C NE  1 
ATOM   6112  C CZ  . ARG C 1 107 ? -17.514 4.686   64.194 1.00 31.12  ? 309 ARG C CZ  1 
ATOM   6113  N NH1 . ARG C 1 107 ? -18.786 4.615   63.831 1.00 32.42  ? 309 ARG C NH1 1 
ATOM   6114  N NH2 . ARG C 1 107 ? -17.113 4.097   65.308 1.00 32.22  ? 309 ARG C NH2 1 
ATOM   6115  N N   . PRO C 1 108 ? -14.916 10.375  60.516 1.00 22.11  ? 310 PRO C N   1 
ATOM   6116  C CA  . PRO C 1 108 ? -14.394 11.432  61.381 1.00 22.10  ? 310 PRO C CA  1 
ATOM   6117  C C   . PRO C 1 108 ? -14.868 11.289  62.817 1.00 23.52  ? 310 PRO C C   1 
ATOM   6118  O O   . PRO C 1 108 ? -15.995 10.876  63.092 1.00 22.82  ? 310 PRO C O   1 
ATOM   6119  C CB  . PRO C 1 108 ? -14.954 12.707  60.743 1.00 20.84  ? 310 PRO C CB  1 
ATOM   6120  C CG  . PRO C 1 108 ? -16.213 12.259  60.097 1.00 19.38  ? 310 PRO C CG  1 
ATOM   6121  C CD  . PRO C 1 108 ? -15.947 10.875  59.593 1.00 19.58  ? 310 PRO C CD  1 
ATOM   6122  N N   . LYS C 1 109 ? -13.981 11.659  63.739 1.00 26.87  ? 311 LYS C N   1 
ATOM   6123  C CA  . LYS C 1 109 ? -14.263 11.584  65.168 1.00 29.19  ? 311 LYS C CA  1 
ATOM   6124  C C   . LYS C 1 109 ? -14.348 12.965  65.798 1.00 29.07  ? 311 LYS C C   1 
ATOM   6125  O O   . LYS C 1 109 ? -15.409 13.343  66.305 1.00 28.94  ? 311 LYS C O   1 
ATOM   6126  C CB  . LYS C 1 109 ? -13.195 10.741  65.875 1.00 22.42  ? 311 LYS C CB  1 
ATOM   6127  C CG  . LYS C 1 109 ? -13.100 9.314   65.384 1.00 29.25  ? 311 LYS C CG  1 
ATOM   6128  C CD  . LYS C 1 109 ? -14.416 8.582   65.557 1.00 36.38  ? 311 LYS C CD  1 
ATOM   6129  C CE  . LYS C 1 109 ? -14.665 8.250   67.017 1.00 41.87  ? 311 LYS C CE  1 
ATOM   6130  N NZ  . LYS C 1 109 ? -15.880 7.414   67.199 1.00 39.83  ? 311 LYS C NZ  1 
ATOM   6131  N N   . ARG C 1 110 ? -13.257 13.725  65.791 1.00 29.24  ? 312 ARG C N   1 
ATOM   6132  C CA  . ARG C 1 110 ? -13.198 15.037  66.409 1.00 30.40  ? 312 ARG C CA  1 
ATOM   6133  C C   . ARG C 1 110 ? -12.774 16.079  65.385 1.00 29.23  ? 312 ARG C C   1 
ATOM   6134  O O   . ARG C 1 110 ? -12.233 15.758  64.326 1.00 28.97  ? 312 ARG C O   1 
ATOM   6135  C CB  . ARG C 1 110 ? -12.228 15.046  67.592 1.00 26.39  ? 312 ARG C CB  1 
ATOM   6136  C CG  . ARG C 1 110 ? -12.673 14.187  68.748 1.00 35.79  ? 312 ARG C CG  1 
ATOM   6137  C CD  . ARG C 1 110 ? -11.654 14.203  69.862 1.00 44.71  ? 312 ARG C CD  1 
ATOM   6138  N NE  . ARG C 1 110 ? -12.098 13.411  71.003 1.00 54.49  ? 312 ARG C NE  1 
ATOM   6139  C CZ  . ARG C 1 110 ? -11.954 12.095  71.100 1.00 59.45  ? 312 ARG C CZ  1 
ATOM   6140  N NH1 . ARG C 1 110 ? -11.375 11.415  70.120 1.00 61.43  ? 312 ARG C NH1 1 
ATOM   6141  N NH2 . ARG C 1 110 ? -12.390 11.457  72.178 1.00 60.61  ? 312 ARG C NH2 1 
ATOM   6142  N N   . LEU C 1 111 ? -13.026 17.339  65.723 1.00 30.68  ? 313 LEU C N   1 
ATOM   6143  C CA  . LEU C 1 111 ? -12.743 18.476  64.862 1.00 29.41  ? 313 LEU C CA  1 
ATOM   6144  C C   . LEU C 1 111 ? -12.260 19.634  65.721 1.00 29.70  ? 313 LEU C C   1 
ATOM   6145  O O   . LEU C 1 111 ? -12.824 19.905  66.784 1.00 29.11  ? 313 LEU C O   1 
ATOM   6146  C CB  . LEU C 1 111 ? -13.993 18.867  64.049 1.00 26.79  ? 313 LEU C CB  1 
ATOM   6147  C CG  . LEU C 1 111 ? -14.107 20.107  63.148 1.00 26.72  ? 313 LEU C CG  1 
ATOM   6148  C CD1 . LEU C 1 111 ? -14.223 21.427  63.908 1.00 28.00  ? 313 LEU C CD1 1 
ATOM   6149  C CD2 . LEU C 1 111 ? -13.003 20.159  62.110 1.00 31.92  ? 313 LEU C CD2 1 
ATOM   6150  N N   . ASN C 1 112 ? -11.216 20.314  65.256 1.00 30.97  ? 314 ASN C N   1 
ATOM   6151  C CA  . ASN C 1 112 ? -10.665 21.459  65.966 1.00 31.52  ? 314 ASN C CA  1 
ATOM   6152  C C   . ASN C 1 112 ? -10.337 22.540  64.948 1.00 30.13  ? 314 ASN C C   1 
ATOM   6153  O O   . ASN C 1 112 ? -9.638  22.279  63.966 1.00 31.81  ? 314 ASN C O   1 
ATOM   6154  C CB  . ASN C 1 112 ? -9.418  21.065  66.765 1.00 30.20  ? 314 ASN C CB  1 
ATOM   6155  C CG  . ASN C 1 112 ? -8.961  22.154  67.715 1.00 36.37  ? 314 ASN C CG  1 
ATOM   6156  O OD1 . ASN C 1 112 ? -9.295  23.326  67.551 1.00 39.38  ? 314 ASN C OD1 1 
ATOM   6157  N ND2 . ASN C 1 112 ? -8.190  21.766  68.721 1.00 40.44  ? 314 ASN C ND2 1 
ATOM   6158  N N   . PHE C 1 113 ? -10.840 23.747  65.188 1.00 33.86  ? 315 PHE C N   1 
ATOM   6159  C CA  . PHE C 1 113 ? -10.737 24.849  64.242 1.00 32.43  ? 315 PHE C CA  1 
ATOM   6160  C C   . PHE C 1 113 ? -10.171 26.065  64.954 1.00 32.77  ? 315 PHE C C   1 
ATOM   6161  O O   . PHE C 1 113 ? -10.761 26.540  65.927 1.00 32.78  ? 315 PHE C O   1 
ATOM   6162  C CB  . PHE C 1 113 ? -12.108 25.182  63.653 1.00 30.61  ? 315 PHE C CB  1 
ATOM   6163  C CG  . PHE C 1 113 ? -12.087 26.294  62.652 1.00 30.01  ? 315 PHE C CG  1 
ATOM   6164  C CD1 . PHE C 1 113 ? -11.845 26.032  61.318 1.00 30.56  ? 315 PHE C CD1 1 
ATOM   6165  C CD2 . PHE C 1 113 ? -12.293 27.605  63.044 1.00 29.60  ? 315 PHE C CD2 1 
ATOM   6166  C CE1 . PHE C 1 113 ? -11.831 27.051  60.393 1.00 30.56  ? 315 PHE C CE1 1 
ATOM   6167  C CE2 . PHE C 1 113 ? -12.271 28.627  62.124 1.00 28.68  ? 315 PHE C CE2 1 
ATOM   6168  C CZ  . PHE C 1 113 ? -12.038 28.351  60.797 1.00 30.15  ? 315 PHE C CZ  1 
ATOM   6169  N N   . LYS C 1 114 ? -9.042  26.576  64.468 1.00 32.82  ? 316 LYS C N   1 
ATOM   6170  C CA  . LYS C 1 114 ? -8.402  27.742  65.054 1.00 33.64  ? 316 LYS C CA  1 
ATOM   6171  C C   . LYS C 1 114 ? -8.354  28.875  64.041 1.00 33.31  ? 316 LYS C C   1 
ATOM   6172  O O   . LYS C 1 114 ? -8.182  28.655  62.840 1.00 34.73  ? 316 LYS C O   1 
ATOM   6173  C CB  . LYS C 1 114 ? -6.987  27.428  65.541 1.00 32.31  ? 316 LYS C CB  1 
ATOM   6174  C CG  . LYS C 1 114 ? -6.933  26.461  66.707 1.00 34.52  ? 316 LYS C CG  1 
ATOM   6175  C CD  . LYS C 1 114 ? -5.502  26.117  67.071 1.00 37.31  ? 316 LYS C CD  1 
ATOM   6176  C CE  . LYS C 1 114 ? -5.448  25.163  68.247 1.00 39.18  ? 316 LYS C CE  1 
ATOM   6177  N NZ  . LYS C 1 114 ? -4.053  24.767  68.578 1.00 43.22  ? 316 LYS C NZ  1 
ATOM   6178  N N   . LEU C 1 115 ? -8.513  30.094  64.546 1.00 37.82  ? 317 LEU C N   1 
ATOM   6179  C CA  . LEU C 1 115 ? -8.507  31.299  63.728 1.00 37.18  ? 317 LEU C CA  1 
ATOM   6180  C C   . LEU C 1 115 ? -7.649  32.329  64.443 1.00 37.46  ? 317 LEU C C   1 
ATOM   6181  O O   . LEU C 1 115 ? -7.968  32.722  65.568 1.00 38.13  ? 317 LEU C O   1 
ATOM   6182  C CB  . LEU C 1 115 ? -9.933  31.813  63.518 1.00 34.64  ? 317 LEU C CB  1 
ATOM   6183  C CG  . LEU C 1 115 ? -10.162 33.071  62.688 1.00 37.74  ? 317 LEU C CG  1 
ATOM   6184  C CD1 . LEU C 1 115 ? -9.724  32.844  61.261 1.00 38.55  ? 317 LEU C CD1 1 
ATOM   6185  C CD2 . LEU C 1 115 ? -11.623 33.457  62.739 1.00 38.84  ? 317 LEU C CD2 1 
ATOM   6186  N N   . PHE C 1 116 ? -6.569  32.767  63.803 1.00 38.65  ? 318 PHE C N   1 
ATOM   6187  C CA  . PHE C 1 116 ? -5.538  33.522  64.504 1.00 39.20  ? 318 PHE C CA  1 
ATOM   6188  C C   . PHE C 1 116 ? -4.767  34.371  63.500 1.00 40.29  ? 318 PHE C C   1 
ATOM   6189  O O   . PHE C 1 116 ? -5.069  34.383  62.304 1.00 41.58  ? 318 PHE C O   1 
ATOM   6190  C CB  . PHE C 1 116 ? -4.616  32.573  65.276 1.00 36.52  ? 318 PHE C CB  1 
ATOM   6191  C CG  . PHE C 1 116 ? -3.950  31.537  64.413 1.00 37.43  ? 318 PHE C CG  1 
ATOM   6192  C CD1 . PHE C 1 116 ? -2.702  31.765  63.867 1.00 37.36  ? 318 PHE C CD1 1 
ATOM   6193  C CD2 . PHE C 1 116 ? -4.584  30.342  64.133 1.00 37.61  ? 318 PHE C CD2 1 
ATOM   6194  C CE1 . PHE C 1 116 ? -2.093  30.815  63.078 1.00 36.73  ? 318 PHE C CE1 1 
ATOM   6195  C CE2 . PHE C 1 116 ? -3.981  29.392  63.338 1.00 37.83  ? 318 PHE C CE2 1 
ATOM   6196  C CZ  . PHE C 1 116 ? -2.735  29.629  62.810 1.00 38.13  ? 318 PHE C CZ  1 
ATOM   6197  N N   . ASN C 1 117 ? -3.758  35.082  64.009 1.00 40.58  ? 319 ASN C N   1 
ATOM   6198  C CA  . ASN C 1 117 ? -2.902  35.961  63.210 1.00 41.00  ? 319 ASN C CA  1 
ATOM   6199  C C   . ASN C 1 117 ? -3.729  36.957  62.405 1.00 41.51  ? 319 ASN C C   1 
ATOM   6200  O O   . ASN C 1 117 ? -3.564  37.114  61.195 1.00 43.60  ? 319 ASN C O   1 
ATOM   6201  C CB  . ASN C 1 117 ? -1.975  35.150  62.307 1.00 40.67  ? 319 ASN C CB  1 
ATOM   6202  C CG  . ASN C 1 117 ? -0.870  34.463  63.080 1.00 43.18  ? 319 ASN C CG  1 
ATOM   6203  O OD1 . ASN C 1 117 ? -0.517  34.884  64.180 1.00 42.36  ? 319 ASN C OD1 1 
ATOM   6204  N ND2 . ASN C 1 117 ? -0.313  33.407  62.508 1.00 44.67  ? 319 ASN C ND2 1 
ATOM   6205  N N   . ILE C 1 118 ? -4.624  37.652  63.106 1.00 43.94  ? 320 ILE C N   1 
ATOM   6206  C CA  . ILE C 1 118 ? -5.534  38.589  62.461 1.00 44.35  ? 320 ILE C CA  1 
ATOM   6207  C C   . ILE C 1 118 ? -4.777  39.842  62.045 1.00 45.35  ? 320 ILE C C   1 
ATOM   6208  O O   . ILE C 1 118 ? -3.986  40.400  62.816 1.00 46.46  ? 320 ILE C O   1 
ATOM   6209  C CB  . ILE C 1 118 ? -6.702  38.928  63.396 1.00 40.83  ? 320 ILE C CB  1 
ATOM   6210  C CG1 . ILE C 1 118 ? -7.470  37.657  63.755 1.00 40.22  ? 320 ILE C CG1 1 
ATOM   6211  C CG2 . ILE C 1 118 ? -7.621  39.946  62.752 1.00 41.21  ? 320 ILE C CG2 1 
ATOM   6212  C CD1 . ILE C 1 118 ? -8.036  36.937  62.557 1.00 42.71  ? 320 ILE C CD1 1 
ATOM   6213  N N   . GLN C 1 119 ? -5.023  40.290  60.819 1.00 43.47  ? 321 GLN C N   1 
ATOM   6214  C CA  . GLN C 1 119 ? -4.410  41.483  60.264 1.00 44.61  ? 321 GLN C CA  1 
ATOM   6215  C C   . GLN C 1 119 ? -5.475  42.267  59.520 1.00 44.84  ? 321 GLN C C   1 
ATOM   6216  O O   . GLN C 1 119 ? -6.164  41.717  58.659 1.00 45.67  ? 321 GLN C O   1 
ATOM   6217  C CB  . GLN C 1 119 ? -3.273  41.124  59.311 1.00 45.88  ? 321 GLN C CB  1 
ATOM   6218  C CG  . GLN C 1 119 ? -2.113  40.406  59.967 1.00 48.17  ? 321 GLN C CG  1 
ATOM   6219  C CD  . GLN C 1 119 ? -1.073  39.959  58.964 1.00 50.48  ? 321 GLN C CD  1 
ATOM   6220  O OE1 . GLN C 1 119 ? -1.370  39.785  57.784 1.00 49.47  ? 321 GLN C OE1 1 
ATOM   6221  N NE2 . GLN C 1 119 ? 0.153   39.761  59.429 1.00 49.63  ? 321 GLN C NE2 1 
ATOM   6222  N N   . VAL C 1 120 ? -5.617  43.546  59.852 1.00 48.91  ? 322 VAL C N   1 
ATOM   6223  C CA  . VAL C 1 120 ? -6.615  44.369  59.180 1.00 49.39  ? 322 VAL C CA  1 
ATOM   6224  C C   . VAL C 1 120 ? -5.924  45.434  58.342 1.00 50.03  ? 322 VAL C C   1 
ATOM   6225  O O   . VAL C 1 120 ? -5.292  46.352  58.875 1.00 50.24  ? 322 VAL C O   1 
ATOM   6226  C CB  . VAL C 1 120 ? -7.591  45.012  60.176 1.00 49.58  ? 322 VAL C CB  1 
ATOM   6227  C CG1 . VAL C 1 120 ? -8.556  45.893  59.425 1.00 49.37  ? 322 VAL C CG1 1 
ATOM   6228  C CG2 . VAL C 1 120 ? -8.334  43.945  60.956 1.00 47.84  ? 322 VAL C CG2 1 
ATOM   6229  N N   . LYS C 1 121 ? -6.051  45.320  57.026 1.00 47.94  ? 323 LYS C N   1 
ATOM   6230  C CA  . LYS C 1 121 ? -5.429  46.279  56.130 1.00 49.80  ? 323 LYS C CA  1 
ATOM   6231  C C   . LYS C 1 121 ? -6.458  47.284  55.633 1.00 51.41  ? 323 LYS C C   1 
ATOM   6232  O O   . LYS C 1 121 ? -7.540  46.910  55.174 1.00 51.56  ? 323 LYS C O   1 
ATOM   6233  C CB  . LYS C 1 121 ? -4.800  45.548  54.947 1.00 47.61  ? 323 LYS C CB  1 
ATOM   6234  C CG  . LYS C 1 121 ? -3.737  44.530  55.315 1.00 48.83  ? 323 LYS C CG  1 
ATOM   6235  C CD  . LYS C 1 121 ? -2.476  45.214  55.785 1.00 50.82  ? 323 LYS C CD  1 
ATOM   6236  C CE  . LYS C 1 121 ? -1.363  44.216  56.034 1.00 51.65  ? 323 LYS C CE  1 
ATOM   6237  N NZ  . LYS C 1 121 ? -1.634  43.346  57.207 1.00 53.42  ? 323 LYS C NZ  1 
ATOM   6238  N N   . GLU C 1 122 ? -6.122  48.568  55.726 1.00 55.06  ? 324 GLU C N   1 
ATOM   6239  C CA  . GLU C 1 122 ? -6.965  49.634  55.199 1.00 59.18  ? 324 GLU C CA  1 
ATOM   6240  C C   . GLU C 1 122 ? -6.388  50.087  53.865 1.00 59.24  ? 324 GLU C C   1 
ATOM   6241  O O   . GLU C 1 122 ? -5.186  50.353  53.759 1.00 59.52  ? 324 GLU C O   1 
ATOM   6242  C CB  . GLU C 1 122 ? -7.080  50.801  56.185 1.00 51.88  ? 324 GLU C CB  1 
ATOM   6243  C CG  . GLU C 1 122 ? -5.776  51.511  56.513 1.00 62.48  ? 324 GLU C CG  1 
ATOM   6244  C CD  . GLU C 1 122 ? -5.941  52.583  57.572 1.00 69.16  ? 324 GLU C CD  1 
ATOM   6245  O OE1 . GLU C 1 122 ? -7.089  53.013  57.811 1.00 72.36  ? 324 GLU C OE1 1 
ATOM   6246  O OE2 . GLU C 1 122 ? -4.922  52.993  58.168 1.00 71.63  ? 324 GLU C OE2 1 
ATOM   6247  N N   . VAL C 1 123 ? -7.237  50.150  52.847 1.00 60.69  ? 325 VAL C N   1 
ATOM   6248  C CA  . VAL C 1 123 ? -6.815  50.546  51.509 1.00 62.36  ? 325 VAL C CA  1 
ATOM   6249  C C   . VAL C 1 123 ? -7.014  52.046  51.365 1.00 64.81  ? 325 VAL C C   1 
ATOM   6250  O O   . VAL C 1 123 ? -8.145  52.541  51.430 1.00 64.39  ? 325 VAL C O   1 
ATOM   6251  C CB  . VAL C 1 123 ? -7.592  49.781  50.429 1.00 62.25  ? 325 VAL C CB  1 
ATOM   6252  C CG1 . VAL C 1 123 ? -7.232  50.306  49.051 1.00 61.09  ? 325 VAL C CG1 1 
ATOM   6253  C CG2 . VAL C 1 123 ? -7.301  48.301  50.522 1.00 61.58  ? 325 VAL C CG2 1 
ATOM   6254  N N   . THR C 1 124 ? -5.916  52.772  51.175 1.00 68.66  ? 326 THR C N   1 
ATOM   6255  C CA  . THR C 1 124 ? -5.945  54.216  50.982 1.00 72.99  ? 326 THR C CA  1 
ATOM   6256  C C   . THR C 1 124 ? -5.662  54.492  49.512 1.00 76.19  ? 326 THR C C   1 
ATOM   6257  O O   . THR C 1 124 ? -4.542  54.273  49.041 1.00 76.09  ? 326 THR C O   1 
ATOM   6258  C CB  . THR C 1 124 ? -4.927  54.915  51.882 1.00 69.82  ? 326 THR C CB  1 
ATOM   6259  O OG1 . THR C 1 124 ? -3.613  54.430  51.585 1.00 71.63  ? 326 THR C OG1 1 
ATOM   6260  C CG2 . THR C 1 124 ? -5.235  54.639  53.344 1.00 69.21  ? 326 THR C CG2 1 
ATOM   6261  N N   . ASP C 1 125 ? -6.677  54.954  48.790 1.00 80.20  ? 327 ASP C N   1 
ATOM   6262  C CA  . ASP C 1 125 ? -6.560  55.295  47.377 1.00 84.89  ? 327 ASP C CA  1 
ATOM   6263  C C   . ASP C 1 125 ? -6.709  56.805  47.249 1.00 86.42  ? 327 ASP C C   1 
ATOM   6264  O O   . ASP C 1 125 ? -7.811  57.341  47.408 1.00 86.34  ? 327 ASP C O   1 
ATOM   6265  C CB  . ASP C 1 125 ? -7.617  54.559  46.554 1.00 81.74  ? 327 ASP C CB  1 
ATOM   6266  C CG  . ASP C 1 125 ? -7.488  54.816  45.063 1.00 85.79  ? 327 ASP C CG  1 
ATOM   6267  O OD1 . ASP C 1 125 ? -6.535  55.506  44.646 1.00 87.57  ? 327 ASP C OD1 1 
ATOM   6268  O OD2 . ASP C 1 125 ? -8.349  54.322  44.304 1.00 87.82  ? 327 ASP C OD2 1 
ATOM   6269  N N   . ASN C 1 126 ? -5.606  57.484  46.948 1.00 87.23  ? 328 ASN C N   1 
ATOM   6270  C CA  . ASN C 1 126 ? -5.581  58.935  46.842 1.00 90.02  ? 328 ASN C CA  1 
ATOM   6271  C C   . ASN C 1 126 ? -5.113  59.322  45.447 1.00 91.23  ? 328 ASN C C   1 
ATOM   6272  O O   . ASN C 1 126 ? -3.956  59.080  45.089 1.00 91.10  ? 328 ASN C O   1 
ATOM   6273  C CB  . ASN C 1 126 ? -4.664  59.542  47.912 1.00 93.22  ? 328 ASN C CB  1 
ATOM   6274  C CG  . ASN C 1 126 ? -4.774  61.057  47.998 1.00 95.18  ? 328 ASN C CG  1 
ATOM   6275  O OD1 . ASN C 1 126 ? -5.210  61.721  47.058 1.00 95.54  ? 328 ASN C OD1 1 
ATOM   6276  N ND2 . ASN C 1 126 ? -4.383  61.609  49.139 1.00 95.73  ? 328 ASN C ND2 1 
ATOM   6277  N N   . ASN C 1 127 ? -6.016  59.920  44.669 1.00 93.02  ? 329 ASN C N   1 
ATOM   6278  C CA  . ASN C 1 127 ? -5.699  60.442  43.338 1.00 94.37  ? 329 ASN C CA  1 
ATOM   6279  C C   . ASN C 1 127 ? -5.215  59.332  42.403 1.00 93.83  ? 329 ASN C C   1 
ATOM   6280  O O   . ASN C 1 127 ? -4.288  59.511  41.611 1.00 94.20  ? 329 ASN C O   1 
ATOM   6281  C CB  . ASN C 1 127 ? -4.675  61.578  43.427 1.00 92.37  ? 329 ASN C CB  1 
ATOM   6282  C CG  . ASN C 1 127 ? -4.569  62.374  42.140 1.00 94.82  ? 329 ASN C CG  1 
ATOM   6283  O OD1 . ASN C 1 127 ? -5.540  62.504  41.395 1.00 95.98  ? 329 ASN C OD1 1 
ATOM   6284  N ND2 . ASN C 1 127 ? -3.385  62.911  41.873 1.00 94.91  ? 329 ASN C ND2 1 
ATOM   6285  N N   . GLY C 1 128 ? -5.850  58.167  42.500 1.00 93.48  ? 330 GLY C N   1 
ATOM   6286  C CA  . GLY C 1 128 ? -5.585  57.075  41.588 1.00 91.70  ? 330 GLY C CA  1 
ATOM   6287  C C   . GLY C 1 128 ? -4.507  56.102  42.013 1.00 90.38  ? 330 GLY C C   1 
ATOM   6288  O O   . GLY C 1 128 ? -4.513  54.959  41.539 1.00 90.80  ? 330 GLY C O   1 
ATOM   6289  N N   . VAL C 1 129 ? -3.585  56.503  42.884 1.00 92.81  ? 331 VAL C N   1 
ATOM   6290  C CA  . VAL C 1 129 ? -2.581  55.602  43.436 1.00 89.28  ? 331 VAL C CA  1 
ATOM   6291  C C   . VAL C 1 129 ? -3.099  55.101  44.776 1.00 87.21  ? 331 VAL C C   1 
ATOM   6292  O O   . VAL C 1 129 ? -3.757  55.847  45.510 1.00 86.86  ? 331 VAL C O   1 
ATOM   6293  C CB  . VAL C 1 129 ? -1.206  56.281  43.585 1.00 87.78  ? 331 VAL C CB  1 
ATOM   6294  C CG1 . VAL C 1 129 ? -0.672  56.692  42.222 1.00 86.50  ? 331 VAL C CG1 1 
ATOM   6295  C CG2 . VAL C 1 129 ? -1.281  57.477  44.515 1.00 87.40  ? 331 VAL C CG2 1 
ATOM   6296  N N   . LYS C 1 130 ? -2.824  53.837  45.082 1.00 83.32  ? 332 LYS C N   1 
ATOM   6297  C CA  . LYS C 1 130 ? -3.394  53.179  46.248 1.00 79.84  ? 332 LYS C CA  1 
ATOM   6298  C C   . LYS C 1 130 ? -2.288  52.674  47.165 1.00 77.20  ? 332 LYS C C   1 
ATOM   6299  O O   . LYS C 1 130 ? -1.317  52.064  46.704 1.00 77.49  ? 332 LYS C O   1 
ATOM   6300  C CB  . LYS C 1 130 ? -4.322  52.039  45.820 1.00 73.61  ? 332 LYS C CB  1 
ATOM   6301  C CG  . LYS C 1 130 ? -3.662  50.953  45.000 1.00 74.08  ? 332 LYS C CG  1 
ATOM   6302  C CD  . LYS C 1 130 ? -4.695  49.955  44.515 1.00 74.52  ? 332 LYS C CD  1 
ATOM   6303  C CE  . LYS C 1 130 ? -5.332  49.209  45.669 1.00 75.34  ? 332 LYS C CE  1 
ATOM   6304  N NZ  . LYS C 1 130 ? -6.367  48.263  45.179 1.00 74.96  ? 332 LYS C NZ  1 
ATOM   6305  N N   . THR C 1 131 ? -2.436  52.947  48.457 1.00 77.19  ? 333 THR C N   1 
ATOM   6306  C CA  . THR C 1 131 ? -1.493  52.533  49.484 1.00 74.20  ? 333 THR C CA  1 
ATOM   6307  C C   . THR C 1 131 ? -2.247  51.765  50.558 1.00 71.15  ? 333 THR C C   1 
ATOM   6308  O O   . THR C 1 131 ? -3.339  52.171  50.970 1.00 71.11  ? 333 THR C O   1 
ATOM   6309  C CB  . THR C 1 131 ? -0.784  53.744  50.101 1.00 74.13  ? 333 THR C CB  1 
ATOM   6310  O OG1 . THR C 1 131 ? -0.060  54.447  49.084 1.00 74.94  ? 333 THR C OG1 1 
ATOM   6311  C CG2 . THR C 1 131 ? 0.178   53.305  51.196 1.00 74.29  ? 333 THR C CG2 1 
ATOM   6312  N N   . ILE C 1 132 ? -1.673  50.654  51.009 1.00 69.82  ? 334 ILE C N   1 
ATOM   6313  C CA  . ILE C 1 132 ? -2.322  49.769  51.968 1.00 65.62  ? 334 ILE C CA  1 
ATOM   6314  C C   . ILE C 1 132 ? -1.562  49.822  53.286 1.00 64.05  ? 334 ILE C C   1 
ATOM   6315  O O   . ILE C 1 132 ? -0.386  49.447  53.349 1.00 64.07  ? 334 ILE C O   1 
ATOM   6316  C CB  . ILE C 1 132 ? -2.410  48.330  51.435 1.00 62.27  ? 334 ILE C CB  1 
ATOM   6317  C CG1 . ILE C 1 132 ? -3.352  48.279  50.231 1.00 61.12  ? 334 ILE C CG1 1 
ATOM   6318  C CG2 . ILE C 1 132 ? -2.891  47.396  52.521 1.00 61.76  ? 334 ILE C CG2 1 
ATOM   6319  C CD1 . ILE C 1 132 ? -3.349  46.962  49.503 1.00 62.05  ? 334 ILE C CD1 1 
ATOM   6320  N N   . ALA C 1 133 ? -2.242  50.274  54.336 1.00 59.31  ? 335 ALA C N   1 
ATOM   6321  C CA  . ALA C 1 133 ? -1.662  50.403  55.663 1.00 58.52  ? 335 ALA C CA  1 
ATOM   6322  C C   . ALA C 1 133 ? -2.501  49.622  56.664 1.00 58.97  ? 335 ALA C C   1 
ATOM   6323  O O   . ALA C 1 133 ? -3.633  49.224  56.381 1.00 60.61  ? 335 ALA C O   1 
ATOM   6324  C CB  . ALA C 1 133 ? -1.559  51.870  56.092 1.00 61.57  ? 335 ALA C CB  1 
ATOM   6325  N N   . ASN C 1 134 ? -1.925  49.393  57.840 1.00 59.00  ? 336 ASN C N   1 
ATOM   6326  C CA  . ASN C 1 134 ? -2.617  48.655  58.887 1.00 59.77  ? 336 ASN C CA  1 
ATOM   6327  C C   . ASN C 1 134 ? -3.620  49.543  59.608 1.00 59.71  ? 336 ASN C C   1 
ATOM   6328  O O   . ASN C 1 134 ? -3.376  50.733  59.830 1.00 59.53  ? 336 ASN C O   1 
ATOM   6329  C CB  . ASN C 1 134 ? -1.625  48.094  59.905 1.00 54.53  ? 336 ASN C CB  1 
ATOM   6330  C CG  . ASN C 1 134 ? -0.755  47.002  59.334 1.00 56.63  ? 336 ASN C CG  1 
ATOM   6331  O OD1 . ASN C 1 134 ? -1.106  46.368  58.345 1.00 59.67  ? 336 ASN C OD1 1 
ATOM   6332  N ND2 . ASN C 1 134 ? 0.387   46.768  59.963 1.00 56.72  ? 336 ASN C ND2 1 
ATOM   6333  N N   . ASN C 1 135 ? -4.754  48.956  59.973 1.00 56.98  ? 337 ASN C N   1 
ATOM   6334  C CA  . ASN C 1 135 ? -5.675  49.552  60.930 1.00 56.88  ? 337 ASN C CA  1 
ATOM   6335  C C   . ASN C 1 135 ? -5.631  48.679  62.178 1.00 55.91  ? 337 ASN C C   1 
ATOM   6336  O O   . ASN C 1 135 ? -6.156  47.562  62.181 1.00 56.87  ? 337 ASN C O   1 
ATOM   6337  C CB  . ASN C 1 135 ? -7.085  49.641  60.349 1.00 54.96  ? 337 ASN C CB  1 
ATOM   6338  C CG  . ASN C 1 135 ? -8.034  50.436  61.227 1.00 58.97  ? 337 ASN C CG  1 
ATOM   6339  O OD1 . ASN C 1 135 ? -7.800  50.615  62.421 1.00 60.68  ? 337 ASN C OD1 1 
ATOM   6340  N ND2 . ASN C 1 135 ? -9.120  50.910  60.635 1.00 62.63  ? 337 ASN C ND2 1 
ATOM   6341  N N   . LEU C 1 136 ? -5.008  49.191  63.239 1.00 56.09  ? 338 LEU C N   1 
ATOM   6342  C CA  . LEU C 1 136 ? -4.725  48.372  64.410 1.00 54.58  ? 338 LEU C CA  1 
ATOM   6343  C C   . LEU C 1 136 ? -5.905  48.250  65.364 1.00 55.09  ? 338 LEU C C   1 
ATOM   6344  O O   . LEU C 1 136 ? -5.946  47.303  66.155 1.00 55.40  ? 338 LEU C O   1 
ATOM   6345  C CB  . LEU C 1 136 ? -3.516  48.938  65.153 1.00 57.20  ? 338 LEU C CB  1 
ATOM   6346  C CG  . LEU C 1 136 ? -2.213  48.895  64.354 1.00 56.37  ? 338 LEU C CG  1 
ATOM   6347  C CD1 . LEU C 1 136 ? -1.093  49.609  65.093 1.00 52.33  ? 338 LEU C CD1 1 
ATOM   6348  C CD2 . LEU C 1 136 ? -1.825  47.456  64.041 1.00 55.57  ? 338 LEU C CD2 1 
ATOM   6349  N N   . THR C 1 137 ? -6.857  49.178  65.317 1.00 54.41  ? 339 THR C N   1 
ATOM   6350  C CA  . THR C 1 137 ? -8.001  49.162  66.217 1.00 54.53  ? 339 THR C CA  1 
ATOM   6351  C C   . THR C 1 137 ? -9.241  48.530  65.602 1.00 53.57  ? 339 THR C C   1 
ATOM   6352  O O   . THR C 1 137 ? -10.297 48.525  66.241 1.00 53.89  ? 339 THR C O   1 
ATOM   6353  C CB  . THR C 1 137 ? -8.323  50.582  66.689 1.00 53.82  ? 339 THR C CB  1 
ATOM   6354  O OG1 . THR C 1 137 ? -8.586  51.418  65.555 1.00 56.09  ? 339 THR C OG1 1 
ATOM   6355  C CG2 . THR C 1 137 ? -7.159  51.152  67.474 1.00 53.75  ? 339 THR C CG2 1 
ATOM   6356  N N   . SER C 1 138 ? -9.151  48.014  64.381 1.00 51.61  ? 340 SER C N   1 
ATOM   6357  C CA  . SER C 1 138 ? -10.301 47.373  63.770 1.00 51.13  ? 340 SER C CA  1 
ATOM   6358  C C   . SER C 1 138 ? -10.532 45.985  64.352 1.00 50.36  ? 340 SER C C   1 
ATOM   6359  O O   . SER C 1 138 ? -9.614  45.323  64.843 1.00 49.89  ? 340 SER C O   1 
ATOM   6360  C CB  . SER C 1 138 ? -10.125 47.264  62.262 1.00 48.62  ? 340 SER C CB  1 
ATOM   6361  O OG  . SER C 1 138 ? -10.154 48.538  61.655 1.00 55.08  ? 340 SER C OG  1 
ATOM   6362  N N   . THR C 1 139 ? -11.784 45.545  64.279 1.00 47.31  ? 341 THR C N   1 
ATOM   6363  C CA  . THR C 1 139 ? -12.190 44.245  64.781 1.00 47.67  ? 341 THR C CA  1 
ATOM   6364  C C   . THR C 1 139 ? -12.781 43.408  63.653 1.00 46.72  ? 341 THR C C   1 
ATOM   6365  O O   . THR C 1 139 ? -13.237 43.927  62.632 1.00 46.39  ? 341 THR C O   1 
ATOM   6366  C CB  . THR C 1 139 ? -13.207 44.376  65.922 1.00 45.42  ? 341 THR C CB  1 
ATOM   6367  O OG1 . THR C 1 139 ? -14.357 45.090  65.460 1.00 46.05  ? 341 THR C OG1 1 
ATOM   6368  C CG2 . THR C 1 139 ? -12.601 45.115  67.099 1.00 48.21  ? 341 THR C CG2 1 
ATOM   6369  N N   . VAL C 1 140 ? -12.752 42.095  63.852 1.00 45.38  ? 342 VAL C N   1 
ATOM   6370  C CA  . VAL C 1 140 ? -13.330 41.129  62.929 1.00 44.48  ? 342 VAL C CA  1 
ATOM   6371  C C   . VAL C 1 140 ? -14.256 40.220  63.721 1.00 43.94  ? 342 VAL C C   1 
ATOM   6372  O O   . VAL C 1 140 ? -13.801 39.454  64.576 1.00 44.56  ? 342 VAL C O   1 
ATOM   6373  C CB  . VAL C 1 140 ? -12.234 40.309  62.214 1.00 43.51  ? 342 VAL C CB  1 
ATOM   6374  C CG1 . VAL C 1 140 ? -12.852 39.226  61.361 1.00 46.16  ? 342 VAL C CG1 1 
ATOM   6375  C CG2 . VAL C 1 140 ? -11.351 41.215  61.370 1.00 44.93  ? 342 VAL C CG2 1 
ATOM   6376  N N   . GLN C 1 141 ? -15.551 40.303  63.441 1.00 39.77  ? 343 GLN C N   1 
ATOM   6377  C CA  . GLN C 1 141 ? -16.550 39.521  64.154 1.00 39.52  ? 343 GLN C CA  1 
ATOM   6378  C C   . GLN C 1 141 ? -16.571 38.096  63.623 1.00 38.76  ? 343 GLN C C   1 
ATOM   6379  O O   . GLN C 1 141 ? -16.497 37.875  62.412 1.00 39.50  ? 343 GLN C O   1 
ATOM   6380  C CB  . GLN C 1 141 ? -17.944 40.138  64.028 1.00 41.04  ? 343 GLN C CB  1 
ATOM   6381  C CG  . GLN C 1 141 ? -18.105 41.456  64.750 1.00 43.31  ? 343 GLN C CG  1 
ATOM   6382  C CD  . GLN C 1 141 ? -19.488 42.042  64.582 1.00 47.17  ? 343 GLN C CD  1 
ATOM   6383  O OE1 . GLN C 1 141 ? -20.193 41.735  63.622 1.00 49.93  ? 343 GLN C OE1 1 
ATOM   6384  N NE2 . GLN C 1 141 ? -19.884 42.897  65.516 1.00 48.42  ? 343 GLN C NE2 1 
ATOM   6385  N N   . VAL C 1 142 ? -16.668 37.135  64.535 1.00 38.84  ? 344 VAL C N   1 
ATOM   6386  C CA  . VAL C 1 142 ? -16.737 35.725  64.178 1.00 38.81  ? 344 VAL C CA  1 
ATOM   6387  C C   . VAL C 1 142 ? -17.659 35.021  65.163 1.00 39.68  ? 344 VAL C C   1 
ATOM   6388  O O   . VAL C 1 142 ? -17.651 35.318  66.362 1.00 40.58  ? 344 VAL C O   1 
ATOM   6389  C CB  . VAL C 1 142 ? -15.334 35.076  64.158 1.00 36.43  ? 344 VAL C CB  1 
ATOM   6390  C CG1 . VAL C 1 142 ? -14.691 35.140  65.526 1.00 35.66  ? 344 VAL C CG1 1 
ATOM   6391  C CG2 . VAL C 1 142 ? -15.415 33.641  63.676 1.00 39.00  ? 344 VAL C CG2 1 
ATOM   6392  N N   . PHE C 1 143 ? -18.477 34.104  64.653 1.00 37.57  ? 345 PHE C N   1 
ATOM   6393  C CA  . PHE C 1 143 ? -19.272 33.255  65.524 1.00 38.00  ? 345 PHE C CA  1 
ATOM   6394  C C   . PHE C 1 143 ? -19.563 31.957  64.791 1.00 38.89  ? 345 PHE C C   1 
ATOM   6395  O O   . PHE C 1 143 ? -19.463 31.876  63.565 1.00 39.36  ? 345 PHE C O   1 
ATOM   6396  C CB  . PHE C 1 143 ? -20.587 33.923  65.958 1.00 38.27  ? 345 PHE C CB  1 
ATOM   6397  C CG  . PHE C 1 143 ? -21.623 34.008  64.872 1.00 38.93  ? 345 PHE C CG  1 
ATOM   6398  C CD1 . PHE C 1 143 ? -22.587 33.023  64.747 1.00 38.31  ? 345 PHE C CD1 1 
ATOM   6399  C CD2 . PHE C 1 143 ? -21.635 35.057  63.979 1.00 39.79  ? 345 PHE C CD2 1 
ATOM   6400  C CE1 . PHE C 1 143 ? -23.542 33.088  63.756 1.00 38.60  ? 345 PHE C CE1 1 
ATOM   6401  C CE2 . PHE C 1 143 ? -22.592 35.125  62.984 1.00 39.87  ? 345 PHE C CE2 1 
ATOM   6402  C CZ  . PHE C 1 143 ? -23.542 34.140  62.873 1.00 39.39  ? 345 PHE C CZ  1 
ATOM   6403  N N   . THR C 1 144 ? -19.925 30.942  65.560 1.00 39.86  ? 346 THR C N   1 
ATOM   6404  C CA  . THR C 1 144 ? -20.382 29.676  65.015 1.00 42.00  ? 346 THR C CA  1 
ATOM   6405  C C   . THR C 1 144 ? -21.818 29.429  65.452 1.00 44.06  ? 346 THR C C   1 
ATOM   6406  O O   . THR C 1 144 ? -22.229 29.831  66.543 1.00 44.15  ? 346 THR C O   1 
ATOM   6407  C CB  . THR C 1 144 ? -19.491 28.523  65.478 1.00 38.38  ? 346 THR C CB  1 
ATOM   6408  O OG1 . THR C 1 144 ? -19.530 28.430  66.906 1.00 41.44  ? 346 THR C OG1 1 
ATOM   6409  C CG2 . THR C 1 144 ? -18.063 28.761  65.041 1.00 38.11  ? 346 THR C CG2 1 
ATOM   6410  N N   . ASP C 1 145 ? -22.578 28.750  64.602 1.00 40.60  ? 347 ASP C N   1 
ATOM   6411  C CA  . ASP C 1 145 ? -23.966 28.442  64.924 1.00 44.00  ? 347 ASP C CA  1 
ATOM   6412  C C   . ASP C 1 145 ? -23.972 26.998  65.407 1.00 44.24  ? 347 ASP C C   1 
ATOM   6413  O O   . ASP C 1 145 ? -23.912 26.055  64.618 1.00 44.08  ? 347 ASP C O   1 
ATOM   6414  C CB  . ASP C 1 145 ? -24.861 28.651  63.708 1.00 42.61  ? 347 ASP C CB  1 
ATOM   6415  C CG  . ASP C 1 145 ? -26.331 28.493  64.028 1.00 48.17  ? 347 ASP C CG  1 
ATOM   6416  O OD1 . ASP C 1 145 ? -26.668 28.304  65.216 1.00 49.19  ? 347 ASP C OD1 1 
ATOM   6417  O OD2 . ASP C 1 145 ? -27.154 28.559  63.091 1.00 50.93  ? 347 ASP C OD2 1 
ATOM   6418  N N   . SER C 1 146 ? -24.068 26.829  66.725 1.00 45.99  ? 348 SER C N   1 
ATOM   6419  C CA  . SER C 1 146 ? -24.053 25.510  67.334 1.00 46.03  ? 348 SER C CA  1 
ATOM   6420  C C   . SER C 1 146 ? -25.442 24.993  67.670 1.00 46.50  ? 348 SER C C   1 
ATOM   6421  O O   . SER C 1 146 ? -25.573 23.834  68.076 1.00 46.44  ? 348 SER C O   1 
ATOM   6422  C CB  . SER C 1 146 ? -23.191 25.527  68.601 1.00 47.47  ? 348 SER C CB  1 
ATOM   6423  O OG  . SER C 1 146 ? -23.733 26.403  69.574 1.00 51.04  ? 348 SER C OG  1 
ATOM   6424  N N   . ASP C 1 147 ? -26.473 25.817  67.514 1.00 44.75  ? 349 ASP C N   1 
ATOM   6425  C CA  . ASP C 1 147 ? -27.853 25.385  67.655 1.00 45.19  ? 349 ASP C CA  1 
ATOM   6426  C C   . ASP C 1 147 ? -28.512 25.104  66.316 1.00 43.07  ? 349 ASP C C   1 
ATOM   6427  O O   . ASP C 1 147 ? -29.701 24.778  66.284 1.00 42.76  ? 349 ASP C O   1 
ATOM   6428  C CB  . ASP C 1 147 ? -28.659 26.431  68.425 1.00 47.51  ? 349 ASP C CB  1 
ATOM   6429  C CG  . ASP C 1 147 ? -28.242 26.529  69.875 1.00 53.38  ? 349 ASP C CG  1 
ATOM   6430  O OD1 . ASP C 1 147 ? -27.545 25.612  70.355 1.00 56.63  ? 349 ASP C OD1 1 
ATOM   6431  O OD2 . ASP C 1 147 ? -28.611 27.520  70.537 1.00 57.29  ? 349 ASP C OD2 1 
ATOM   6432  N N   . TYR C 1 148 ? -27.773 25.252  65.216 1.00 42.68  ? 350 TYR C N   1 
ATOM   6433  C CA  . TYR C 1 148 ? -28.270 24.960  63.873 1.00 40.70  ? 350 TYR C CA  1 
ATOM   6434  C C   . TYR C 1 148 ? -29.498 25.803  63.546 1.00 40.10  ? 350 TYR C C   1 
ATOM   6435  O O   . TYR C 1 148 ? -30.448 25.337  62.916 1.00 40.32  ? 350 TYR C O   1 
ATOM   6436  C CB  . TYR C 1 148 ? -28.564 23.468  63.714 1.00 35.84  ? 350 TYR C CB  1 
ATOM   6437  C CG  . TYR C 1 148 ? -27.341 22.611  63.918 1.00 35.93  ? 350 TYR C CG  1 
ATOM   6438  C CD1 . TYR C 1 148 ? -26.486 22.329  62.866 1.00 36.63  ? 350 TYR C CD1 1 
ATOM   6439  C CD2 . TYR C 1 148 ? -27.031 22.101  65.168 1.00 34.66  ? 350 TYR C CD2 1 
ATOM   6440  C CE1 . TYR C 1 148 ? -25.364 21.556  63.052 1.00 36.52  ? 350 TYR C CE1 1 
ATOM   6441  C CE2 . TYR C 1 148 ? -25.914 21.326  65.364 1.00 34.58  ? 350 TYR C CE2 1 
ATOM   6442  C CZ  . TYR C 1 148 ? -25.083 21.056  64.303 1.00 36.21  ? 350 TYR C CZ  1 
ATOM   6443  O OH  . TYR C 1 148 ? -23.965 20.282  64.494 1.00 37.90  ? 350 TYR C OH  1 
ATOM   6444  N N   . GLN C 1 149 ? -29.477 27.059  63.985 1.00 43.65  ? 351 GLN C N   1 
ATOM   6445  C CA  . GLN C 1 149 ? -30.588 27.972  63.769 1.00 43.48  ? 351 GLN C CA  1 
ATOM   6446  C C   . GLN C 1 149 ? -30.591 28.597  62.381 1.00 43.10  ? 351 GLN C C   1 
ATOM   6447  O O   . GLN C 1 149 ? -31.667 28.910  61.862 1.00 45.19  ? 351 GLN C O   1 
ATOM   6448  C CB  . GLN C 1 149 ? -30.567 29.069  64.837 1.00 43.11  ? 351 GLN C CB  1 
ATOM   6449  C CG  . GLN C 1 149 ? -30.813 28.539  66.239 1.00 43.94  ? 351 GLN C CG  1 
ATOM   6450  C CD  . GLN C 1 149 ? -30.666 29.600  67.307 1.00 46.30  ? 351 GLN C CD  1 
ATOM   6451  O OE1 . GLN C 1 149 ? -29.972 30.595  67.118 1.00 48.64  ? 351 GLN C OE1 1 
ATOM   6452  N NE2 . GLN C 1 149 ? -31.320 29.391  68.443 1.00 46.01  ? 351 GLN C NE2 1 
ATOM   6453  N N   . LEU C 1 150 ? -29.429 28.775  61.769 1.00 40.69  ? 352 LEU C N   1 
ATOM   6454  C CA  . LEU C 1 150 ? -29.332 29.358  60.440 1.00 39.34  ? 352 LEU C CA  1 
ATOM   6455  C C   . LEU C 1 150 ? -29.448 28.292  59.364 1.00 39.36  ? 352 LEU C C   1 
ATOM   6456  O O   . LEU C 1 150 ? -29.206 27.108  59.615 1.00 40.30  ? 352 LEU C O   1 
ATOM   6457  C CB  . LEU C 1 150 ? -28.005 30.098  60.285 1.00 40.54  ? 352 LEU C CB  1 
ATOM   6458  C CG  . LEU C 1 150 ? -27.827 31.360  61.116 1.00 41.22  ? 352 LEU C CG  1 
ATOM   6459  C CD1 . LEU C 1 150 ? -26.419 31.890  60.963 1.00 40.71  ? 352 LEU C CD1 1 
ATOM   6460  C CD2 . LEU C 1 150 ? -28.844 32.394  60.681 1.00 39.49  ? 352 LEU C CD2 1 
ATOM   6461  N N   . PRO C 1 151 ? -29.828 28.685  58.150 1.00 38.06  ? 353 PRO C N   1 
ATOM   6462  C CA  . PRO C 1 151 ? -29.796 27.743  57.028 1.00 37.04  ? 353 PRO C CA  1 
ATOM   6463  C C   . PRO C 1 151 ? -28.404 27.164  56.841 1.00 37.51  ? 353 PRO C C   1 
ATOM   6464  O O   . PRO C 1 151 ? -27.395 27.833  57.068 1.00 37.37  ? 353 PRO C O   1 
ATOM   6465  C CB  . PRO C 1 151 ? -30.215 28.605  55.836 1.00 37.11  ? 353 PRO C CB  1 
ATOM   6466  C CG  . PRO C 1 151 ? -31.068 29.660  56.440 1.00 36.69  ? 353 PRO C CG  1 
ATOM   6467  C CD  . PRO C 1 151 ? -30.466 29.959  57.779 1.00 36.80  ? 353 PRO C CD  1 
ATOM   6468  N N   . TYR C 1 152 ? -28.355 25.906  56.424 1.00 32.90  ? 354 TYR C N   1 
ATOM   6469  C CA  . TYR C 1 152 ? -27.105 25.164  56.331 1.00 33.49  ? 354 TYR C CA  1 
ATOM   6470  C C   . TYR C 1 152 ? -26.752 25.029  54.853 1.00 34.92  ? 354 TYR C C   1 
ATOM   6471  O O   . TYR C 1 152 ? -27.392 24.271  54.120 1.00 36.40  ? 354 TYR C O   1 
ATOM   6472  C CB  . TYR C 1 152 ? -27.256 23.806  57.009 1.00 29.92  ? 354 TYR C CB  1 
ATOM   6473  C CG  . TYR C 1 152 ? -25.999 22.984  57.101 1.00 30.92  ? 354 TYR C CG  1 
ATOM   6474  C CD1 . TYR C 1 152 ? -25.089 23.188  58.125 1.00 30.93  ? 354 TYR C CD1 1 
ATOM   6475  C CD2 . TYR C 1 152 ? -25.721 22.003  56.167 1.00 30.39  ? 354 TYR C CD2 1 
ATOM   6476  C CE1 . TYR C 1 152 ? -23.942 22.431  58.219 1.00 32.06  ? 354 TYR C CE1 1 
ATOM   6477  C CE2 . TYR C 1 152 ? -24.576 21.245  56.250 1.00 31.69  ? 354 TYR C CE2 1 
ATOM   6478  C CZ  . TYR C 1 152 ? -23.692 21.462  57.278 1.00 33.40  ? 354 TYR C CZ  1 
ATOM   6479  O OH  . TYR C 1 152 ? -22.548 20.707  57.365 1.00 34.24  ? 354 TYR C OH  1 
ATOM   6480  N N   . VAL C 1 153 ? -25.736 25.778  54.419 1.00 32.89  ? 355 VAL C N   1 
ATOM   6481  C CA  . VAL C 1 153 ? -25.337 25.821  53.018 1.00 32.99  ? 355 VAL C CA  1 
ATOM   6482  C C   . VAL C 1 153 ? -24.146 24.926  52.713 1.00 34.33  ? 355 VAL C C   1 
ATOM   6483  O O   . VAL C 1 153 ? -23.672 24.914  51.570 1.00 34.22  ? 355 VAL C O   1 
ATOM   6484  C CB  . VAL C 1 153 ? -25.038 27.267  52.578 1.00 31.09  ? 355 VAL C CB  1 
ATOM   6485  C CG1 . VAL C 1 153 ? -26.286 28.118  52.695 1.00 32.89  ? 355 VAL C CG1 1 
ATOM   6486  C CG2 . VAL C 1 153 ? -23.912 27.854  53.405 1.00 29.92  ? 355 VAL C CG2 1 
ATOM   6487  N N   . LEU C 1 154 ? -23.640 24.180  53.696 1.00 30.66  ? 356 LEU C N   1 
ATOM   6488  C CA  . LEU C 1 154 ? -22.395 23.444  53.508 1.00 32.14  ? 356 LEU C CA  1 
ATOM   6489  C C   . LEU C 1 154 ? -22.585 22.078  52.865 1.00 34.56  ? 356 LEU C C   1 
ATOM   6490  O O   . LEU C 1 154 ? -21.593 21.369  52.676 1.00 36.71  ? 356 LEU C O   1 
ATOM   6491  C CB  . LEU C 1 154 ? -21.679 23.264  54.845 1.00 33.12  ? 356 LEU C CB  1 
ATOM   6492  C CG  . LEU C 1 154 ? -21.171 24.519  55.552 1.00 31.86  ? 356 LEU C CG  1 
ATOM   6493  C CD1 . LEU C 1 154 ? -20.574 24.151  56.897 1.00 31.51  ? 356 LEU C CD1 1 
ATOM   6494  C CD2 . LEU C 1 154 ? -20.152 25.239  54.691 1.00 30.95  ? 356 LEU C CD2 1 
ATOM   6495  N N   . GLY C 1 155 ? -23.810 21.683  52.534 1.00 31.40  ? 357 GLY C N   1 
ATOM   6496  C CA  . GLY C 1 155 ? -24.027 20.350  52.009 1.00 33.16  ? 357 GLY C CA  1 
ATOM   6497  C C   . GLY C 1 155 ? -24.345 20.279  50.530 1.00 32.47  ? 357 GLY C C   1 
ATOM   6498  O O   . GLY C 1 155 ? -24.693 19.211  50.021 1.00 31.30  ? 357 GLY C O   1 
ATOM   6499  N N   . SER C 1 156 ? -24.243 21.405  49.828 1.00 34.45  ? 358 SER C N   1 
ATOM   6500  C CA  . SER C 1 156 ? -24.610 21.481  48.421 1.00 31.77  ? 358 SER C CA  1 
ATOM   6501  C C   . SER C 1 156 ? -23.413 21.358  47.484 1.00 31.30  ? 358 SER C C   1 
ATOM   6502  O O   . SER C 1 156 ? -23.573 21.519  46.270 1.00 30.90  ? 358 SER C O   1 
ATOM   6503  C CB  . SER C 1 156 ? -25.370 22.776  48.145 1.00 30.95  ? 358 SER C CB  1 
ATOM   6504  O OG  . SER C 1 156 ? -26.608 22.792  48.834 1.00 32.94  ? 358 SER C OG  1 
ATOM   6505  N N   . ALA C 1 157 ? -22.251 21.005  48.030 1.00 27.85  ? 359 ALA C N   1 
ATOM   6506  C CA  . ALA C 1 157 ? -20.991 20.874  47.277 1.00 26.36  ? 359 ALA C CA  1 
ATOM   6507  C C   . ALA C 1 157 ? -20.606 22.158  46.535 1.00 26.45  ? 359 ALA C C   1 
ATOM   6508  O O   . ALA C 1 157 ? -20.260 22.144  45.360 1.00 26.11  ? 359 ALA C O   1 
ATOM   6509  C CB  . ALA C 1 157 ? -20.976 19.653  46.357 1.00 21.76  ? 359 ALA C CB  1 
ATOM   6510  N N   . HIS C 1 158 ? -20.687 23.266  47.261 1.00 26.80  ? 360 HIS C N   1 
ATOM   6511  C CA  . HIS C 1 158 ? -20.361 24.593  46.766 1.00 27.64  ? 360 HIS C CA  1 
ATOM   6512  C C   . HIS C 1 158 ? -18.872 24.854  46.700 1.00 29.67  ? 360 HIS C C   1 
ATOM   6513  O O   . HIS C 1 158 ? -18.091 24.181  47.357 1.00 30.45  ? 360 HIS C O   1 
ATOM   6514  C CB  . HIS C 1 158 ? -20.989 25.655  47.660 1.00 27.02  ? 360 HIS C CB  1 
ATOM   6515  C CG  . HIS C 1 158 ? -22.440 25.879  47.402 1.00 28.81  ? 360 HIS C CG  1 
ATOM   6516  N ND1 . HIS C 1 158 ? -22.952 26.031  46.134 1.00 28.93  ? 360 HIS C ND1 1 
ATOM   6517  C CD2 . HIS C 1 158 ? -23.487 25.997  48.248 1.00 30.07  ? 360 HIS C CD2 1 
ATOM   6518  C CE1 . HIS C 1 158 ? -24.255 26.220  46.209 1.00 29.86  ? 360 HIS C CE1 1 
ATOM   6519  N NE2 . HIS C 1 158 ? -24.605 26.204  47.481 1.00 30.60  ? 360 HIS C NE2 1 
ATOM   6520  N N   . GLU C 1 159 ? -18.495 25.852  45.909 1.00 28.97  ? 361 GLU C N   1 
ATOM   6521  C CA  . GLU C 1 159 ? -17.107 26.280  45.743 1.00 31.11  ? 361 GLU C CA  1 
ATOM   6522  C C   . GLU C 1 159 ? -16.668 27.189  46.895 1.00 30.77  ? 361 GLU C C   1 
ATOM   6523  O O   . GLU C 1 159 ? -17.479 27.558  47.741 1.00 30.81  ? 361 GLU C O   1 
ATOM   6524  C CB  . GLU C 1 159 ? -16.929 26.998  44.412 1.00 27.44  ? 361 GLU C CB  1 
ATOM   6525  C CG  . GLU C 1 159 ? -15.566 26.796  43.783 1.00 37.41  ? 361 GLU C CG  1 
ATOM   6526  C CD  . GLU C 1 159 ? -15.505 25.571  42.895 1.00 42.09  ? 361 GLU C CD  1 
ATOM   6527  O OE1 . GLU C 1 159 ? -16.161 25.576  41.832 1.00 44.11  ? 361 GLU C OE1 1 
ATOM   6528  O OE2 . GLU C 1 159 ? -14.789 24.612  43.244 1.00 43.96  ? 361 GLU C OE2 1 
ATOM   6529  N N   . GLY C 1 160 ? -15.390 27.554  46.937 1.00 33.16  ? 362 GLY C N   1 
ATOM   6530  C CA  . GLY C 1 160 ? -14.905 28.421  48.000 1.00 32.54  ? 362 GLY C CA  1 
ATOM   6531  C C   . GLY C 1 160 ? -14.299 27.768  49.228 1.00 32.25  ? 362 GLY C C   1 
ATOM   6532  O O   . GLY C 1 160 ? -14.115 28.411  50.260 1.00 32.19  ? 362 GLY C O   1 
ATOM   6533  N N   . CYS C 1 161 ? -14.028 26.475  49.123 1.00 34.05  ? 363 CYS C N   1 
ATOM   6534  C CA  . CYS C 1 161 ? -13.424 25.677  50.181 1.00 34.23  ? 363 CYS C CA  1 
ATOM   6535  C C   . CYS C 1 161 ? -11.926 25.922  50.299 1.00 31.78  ? 363 CYS C C   1 
ATOM   6536  O O   . CYS C 1 161 ? -11.326 26.566  49.447 1.00 31.26  ? 363 CYS C O   1 
ATOM   6537  C CB  . CYS C 1 161 ? -13.622 24.206  49.852 1.00 32.94  ? 363 CYS C CB  1 
ATOM   6538  S SG  . CYS C 1 161 ? -12.732 23.703  48.354 1.00 42.02  ? 363 CYS C SG  1 
ATOM   6539  N N   . LEU C 1 162 ? -11.312 25.422  51.369 1.00 29.22  ? 364 LEU C N   1 
ATOM   6540  C CA  . LEU C 1 162 ? -9.861  25.533  51.546 1.00 28.12  ? 364 LEU C CA  1 
ATOM   6541  C C   . LEU C 1 162 ? -9.121  24.885  50.366 1.00 27.78  ? 364 LEU C C   1 
ATOM   6542  O O   . LEU C 1 162 ? -9.528  23.841  49.866 1.00 27.83  ? 364 LEU C O   1 
ATOM   6543  C CB  . LEU C 1 162 ? -9.421  24.860  52.842 1.00 25.37  ? 364 LEU C CB  1 
ATOM   6544  C CG  . LEU C 1 162 ? -9.541  25.634  54.150 1.00 26.10  ? 364 LEU C CG  1 
ATOM   6545  C CD1 . LEU C 1 162 ? -10.986 26.025  54.396 1.00 25.55  ? 364 LEU C CD1 1 
ATOM   6546  C CD2 . LEU C 1 162 ? -9.019  24.780  55.290 1.00 24.84  ? 364 LEU C CD2 1 
ATOM   6547  N N   . PRO C 1 163 ? -7.980  25.461  49.955 1.00 27.71  ? 365 PRO C N   1 
ATOM   6548  C CA  . PRO C 1 163 ? -7.283  24.924  48.793 1.00 26.85  ? 365 PRO C CA  1 
ATOM   6549  C C   . PRO C 1 163 ? -6.672  23.570  49.101 1.00 26.11  ? 365 PRO C C   1 
ATOM   6550  O O   . PRO C 1 163 ? -6.348  23.268  50.262 1.00 26.24  ? 365 PRO C O   1 
ATOM   6551  C CB  . PRO C 1 163 ? -6.195  25.977  48.517 1.00 26.70  ? 365 PRO C CB  1 
ATOM   6552  C CG  . PRO C 1 163 ? -6.698  27.212  49.148 1.00 27.19  ? 365 PRO C CG  1 
ATOM   6553  C CD  . PRO C 1 163 ? -7.413  26.750  50.377 1.00 26.38  ? 365 PRO C CD  1 
ATOM   6554  N N   . PRO C 1 164 ? -6.504  22.712  48.092 1.00 23.53  ? 366 PRO C N   1 
ATOM   6555  C CA  . PRO C 1 164 ? -5.789  21.449  48.327 1.00 23.08  ? 366 PRO C CA  1 
ATOM   6556  C C   . PRO C 1 164 ? -4.338  21.667  48.688 1.00 23.48  ? 366 PRO C C   1 
ATOM   6557  O O   . PRO C 1 164 ? -3.780  20.926  49.503 1.00 23.64  ? 366 PRO C O   1 
ATOM   6558  C CB  . PRO C 1 164 ? -5.920  20.725  46.983 1.00 20.82  ? 366 PRO C CB  1 
ATOM   6559  C CG  . PRO C 1 164 ? -7.065  21.361  46.304 1.00 20.90  ? 366 PRO C CG  1 
ATOM   6560  C CD  . PRO C 1 164 ? -7.053  22.787  46.730 1.00 21.12  ? 366 PRO C CD  1 
ATOM   6561  N N   . PHE C 1 165 ? -3.718  22.680  48.104 1.00 23.02  ? 367 PHE C N   1 
ATOM   6562  C CA  . PHE C 1 165 ? -2.280  22.859  48.204 1.00 23.96  ? 367 PHE C CA  1 
ATOM   6563  C C   . PHE C 1 165 ? -1.955  23.862  49.305 1.00 24.94  ? 367 PHE C C   1 
ATOM   6564  O O   . PHE C 1 165 ? -2.492  24.973  49.301 1.00 24.77  ? 367 PHE C O   1 
ATOM   6565  C CB  . PHE C 1 165 ? -1.728  23.316  46.862 1.00 20.02  ? 367 PHE C CB  1 
ATOM   6566  C CG  . PHE C 1 165 ? -0.242  23.471  46.831 1.00 21.34  ? 367 PHE C CG  1 
ATOM   6567  C CD1 . PHE C 1 165 ? 0.577   22.358  46.872 1.00 22.06  ? 367 PHE C CD1 1 
ATOM   6568  C CD2 . PHE C 1 165 ? 0.337   24.716  46.682 1.00 21.44  ? 367 PHE C CD2 1 
ATOM   6569  C CE1 . PHE C 1 165 ? 1.945   22.488  46.824 1.00 22.68  ? 367 PHE C CE1 1 
ATOM   6570  C CE2 . PHE C 1 165 ? 1.707   24.849  46.620 1.00 22.15  ? 367 PHE C CE2 1 
ATOM   6571  C CZ  . PHE C 1 165 ? 2.511   23.736  46.697 1.00 22.82  ? 367 PHE C CZ  1 
ATOM   6572  N N   . PRO C 1 166 ? -1.088  23.505  50.258 1.00 25.24  ? 368 PRO C N   1 
ATOM   6573  C CA  . PRO C 1 166 ? -0.935  24.339  51.464 1.00 25.53  ? 368 PRO C CA  1 
ATOM   6574  C C   . PRO C 1 166 ? -0.422  25.746  51.204 1.00 26.35  ? 368 PRO C C   1 
ATOM   6575  O O   . PRO C 1 166 ? -0.559  26.610  52.078 1.00 27.54  ? 368 PRO C O   1 
ATOM   6576  C CB  . PRO C 1 166 ? 0.054   23.528  52.310 1.00 24.28  ? 368 PRO C CB  1 
ATOM   6577  C CG  . PRO C 1 166 ? -0.122  22.125  51.849 1.00 24.66  ? 368 PRO C CG  1 
ATOM   6578  C CD  . PRO C 1 166 ? -0.374  22.226  50.380 1.00 24.97  ? 368 PRO C CD  1 
ATOM   6579  N N   . ALA C 1 167 ? 0.167   26.009  50.037 1.00 25.44  ? 369 ALA C N   1 
ATOM   6580  C CA  . ALA C 1 167 ? 0.761   27.320  49.807 1.00 25.62  ? 369 ALA C CA  1 
ATOM   6581  C C   . ALA C 1 167 ? -0.206  28.263  49.103 1.00 26.65  ? 369 ALA C C   1 
ATOM   6582  O O   . ALA C 1 167 ? 0.167   29.387  48.748 1.00 27.14  ? 369 ALA C O   1 
ATOM   6583  C CB  . ALA C 1 167 ? 2.049   27.184  49.002 1.00 27.30  ? 369 ALA C CB  1 
ATOM   6584  N N   . ASP C 1 168 ? -1.442  27.829  48.875 1.00 29.03  ? 370 ASP C N   1 
ATOM   6585  C CA  . ASP C 1 168 ? -2.410  28.703  48.228 1.00 31.24  ? 370 ASP C CA  1 
ATOM   6586  C C   . ASP C 1 168 ? -3.148  29.555  49.254 1.00 29.23  ? 370 ASP C C   1 
ATOM   6587  O O   . ASP C 1 168 ? -3.474  29.104  50.355 1.00 29.52  ? 370 ASP C O   1 
ATOM   6588  C CB  . ASP C 1 168 ? -3.414  27.894  47.407 1.00 27.51  ? 370 ASP C CB  1 
ATOM   6589  C CG  . ASP C 1 168 ? -2.805  27.311  46.153 1.00 33.74  ? 370 ASP C CG  1 
ATOM   6590  O OD1 . ASP C 1 168 ? -1.695  27.738  45.779 1.00 36.30  ? 370 ASP C OD1 1 
ATOM   6591  O OD2 . ASP C 1 168 ? -3.445  26.438  45.529 1.00 36.69  ? 370 ASP C OD2 1 
ATOM   6592  N N   . VAL C 1 169 ? -3.406  30.806  48.879 1.00 35.68  ? 371 VAL C N   1 
ATOM   6593  C CA  . VAL C 1 169 ? -4.180  31.745  49.683 1.00 32.62  ? 371 VAL C CA  1 
ATOM   6594  C C   . VAL C 1 169 ? -5.559  31.866  49.054 1.00 32.16  ? 371 VAL C C   1 
ATOM   6595  O O   . VAL C 1 169 ? -5.678  32.224  47.877 1.00 32.04  ? 371 VAL C O   1 
ATOM   6596  C CB  . VAL C 1 169 ? -3.493  33.119  49.768 1.00 31.54  ? 371 VAL C CB  1 
ATOM   6597  C CG1 . VAL C 1 169 ? -4.360  34.098  50.536 1.00 30.24  ? 371 VAL C CG1 1 
ATOM   6598  C CG2 . VAL C 1 169 ? -2.125  32.986  50.411 1.00 30.60  ? 371 VAL C CG2 1 
ATOM   6599  N N   . PHE C 1 170 ? -6.597  31.580  49.834 1.00 30.54  ? 372 PHE C N   1 
ATOM   6600  C CA  . PHE C 1 170 ? -7.942  31.483  49.296 1.00 30.67  ? 372 PHE C CA  1 
ATOM   6601  C C   . PHE C 1 170 ? -8.784  32.653  49.776 1.00 31.31  ? 372 PHE C C   1 
ATOM   6602  O O   . PHE C 1 170 ? -8.542  33.234  50.837 1.00 31.21  ? 372 PHE C O   1 
ATOM   6603  C CB  . PHE C 1 170 ? -8.622  30.165  49.690 1.00 30.28  ? 372 PHE C CB  1 
ATOM   6604  C CG  . PHE C 1 170 ? -8.980  30.062  51.147 1.00 30.46  ? 372 PHE C CG  1 
ATOM   6605  C CD1 . PHE C 1 170 ? -10.249 30.403  51.583 1.00 29.99  ? 372 PHE C CD1 1 
ATOM   6606  C CD2 . PHE C 1 170 ? -8.057  29.628  52.077 1.00 30.73  ? 372 PHE C CD2 1 
ATOM   6607  C CE1 . PHE C 1 170 ? -10.588 30.306  52.913 1.00 29.87  ? 372 PHE C CE1 1 
ATOM   6608  C CE2 . PHE C 1 170 ? -8.394  29.528  53.409 1.00 30.17  ? 372 PHE C CE2 1 
ATOM   6609  C CZ  . PHE C 1 170 ? -9.660  29.867  53.827 1.00 29.50  ? 372 PHE C CZ  1 
ATOM   6610  N N   . MET C 1 171 ? -9.768  33.000  48.960 1.00 35.07  ? 373 MET C N   1 
ATOM   6611  C CA  . MET C 1 171 ? -10.740 34.032  49.276 1.00 34.93  ? 373 MET C CA  1 
ATOM   6612  C C   . MET C 1 171 ? -11.956 33.387  49.925 1.00 33.24  ? 373 MET C C   1 
ATOM   6613  O O   . MET C 1 171 ? -12.407 32.322  49.496 1.00 34.45  ? 373 MET C O   1 
ATOM   6614  C CB  . MET C 1 171 ? -11.138 34.781  48.008 1.00 32.79  ? 373 MET C CB  1 
ATOM   6615  C CG  . MET C 1 171 ? -12.115 35.904  48.210 1.00 37.49  ? 373 MET C CG  1 
ATOM   6616  S SD  . MET C 1 171 ? -12.327 36.818  46.679 1.00 42.54  ? 373 MET C SD  1 
ATOM   6617  C CE  . MET C 1 171 ? -13.614 37.958  47.153 1.00 44.45  ? 373 MET C CE  1 
ATOM   6618  N N   . ILE C 1 172 ? -12.477 34.026  50.962 1.00 34.51  ? 374 ILE C N   1 
ATOM   6619  C CA  . ILE C 1 172 ? -13.611 33.466  51.700 1.00 33.18  ? 374 ILE C CA  1 
ATOM   6620  C C   . ILE C 1 172 ? -14.885 33.669  50.884 1.00 32.51  ? 374 ILE C C   1 
ATOM   6621  O O   . ILE C 1 172 ? -15.091 34.762  50.337 1.00 33.09  ? 374 ILE C O   1 
ATOM   6622  C CB  . ILE C 1 172 ? -13.726 34.110  53.077 1.00 30.79  ? 374 ILE C CB  1 
ATOM   6623  C CG1 . ILE C 1 172 ? -12.584 33.636  53.972 1.00 31.87  ? 374 ILE C CG1 1 
ATOM   6624  C CG2 . ILE C 1 172 ? -15.066 33.806  53.716 1.00 30.01  ? 374 ILE C CG2 1 
ATOM   6625  C CD1 . ILE C 1 172 ? -12.527 34.348  55.287 1.00 36.02  ? 374 ILE C CD1 1 
ATOM   6626  N N   . PRO C 1 173 ? -15.738 32.657  50.765 1.00 30.13  ? 375 PRO C N   1 
ATOM   6627  C CA  . PRO C 1 173 ? -17.006 32.829  50.054 1.00 30.26  ? 375 PRO C CA  1 
ATOM   6628  C C   . PRO C 1 173 ? -18.015 33.633  50.862 1.00 30.58  ? 375 PRO C C   1 
ATOM   6629  O O   . PRO C 1 173 ? -17.953 33.720  52.089 1.00 31.29  ? 375 PRO C O   1 
ATOM   6630  C CB  . PRO C 1 173 ? -17.489 31.391  49.849 1.00 30.57  ? 375 PRO C CB  1 
ATOM   6631  C CG  . PRO C 1 173 ? -16.864 30.637  50.966 1.00 30.17  ? 375 PRO C CG  1 
ATOM   6632  C CD  . PRO C 1 173 ? -15.524 31.260  51.176 1.00 30.55  ? 375 PRO C CD  1 
ATOM   6633  N N   . GLN C 1 174 ? -18.959 34.224  50.138 1.00 32.43  ? 376 GLN C N   1 
ATOM   6634  C CA  . GLN C 1 174 ? -19.961 35.082  50.749 1.00 31.73  ? 376 GLN C CA  1 
ATOM   6635  C C   . GLN C 1 174 ? -21.179 34.273  51.166 1.00 31.98  ? 376 GLN C C   1 
ATOM   6636  O O   . GLN C 1 174 ? -21.705 33.469  50.391 1.00 32.26  ? 376 GLN C O   1 
ATOM   6637  C CB  . GLN C 1 174 ? -20.387 36.181  49.781 1.00 30.83  ? 376 GLN C CB  1 
ATOM   6638  C CG  . GLN C 1 174 ? -21.332 37.185  50.395 1.00 31.31  ? 376 GLN C CG  1 
ATOM   6639  C CD  . GLN C 1 174 ? -21.694 38.296  49.444 1.00 33.69  ? 376 GLN C CD  1 
ATOM   6640  O OE1 . GLN C 1 174 ? -21.191 38.356  48.324 1.00 35.06  ? 376 GLN C OE1 1 
ATOM   6641  N NE2 . GLN C 1 174 ? -22.569 39.188  49.885 1.00 34.33  ? 376 GLN C NE2 1 
ATOM   6642  N N   . TYR C 1 175 ? -21.636 34.502  52.392 1.00 32.00  ? 377 TYR C N   1 
ATOM   6643  C CA  . TYR C 1 175 ? -22.763 33.763  52.936 1.00 31.24  ? 377 TYR C CA  1 
ATOM   6644  C C   . TYR C 1 175 ? -24.081 34.364  52.476 1.00 32.07  ? 377 TYR C C   1 
ATOM   6645  O O   . TYR C 1 175 ? -24.347 35.550  52.684 1.00 32.46  ? 377 TYR C O   1 
ATOM   6646  C CB  . TYR C 1 175 ? -22.718 33.743  54.462 1.00 33.88  ? 377 TYR C CB  1 
ATOM   6647  C CG  . TYR C 1 175 ? -23.926 33.079  55.076 1.00 34.14  ? 377 TYR C CG  1 
ATOM   6648  C CD1 . TYR C 1 175 ? -24.052 31.699  55.083 1.00 33.82  ? 377 TYR C CD1 1 
ATOM   6649  C CD2 . TYR C 1 175 ? -24.941 33.831  55.646 1.00 34.11  ? 377 TYR C CD2 1 
ATOM   6650  C CE1 . TYR C 1 175 ? -25.153 31.088  55.636 1.00 33.84  ? 377 TYR C CE1 1 
ATOM   6651  C CE2 . TYR C 1 175 ? -26.044 33.227  56.204 1.00 34.07  ? 377 TYR C CE2 1 
ATOM   6652  C CZ  . TYR C 1 175 ? -26.145 31.856  56.196 1.00 34.92  ? 377 TYR C CZ  1 
ATOM   6653  O OH  . TYR C 1 175 ? -27.247 31.252  56.750 1.00 34.81  ? 377 TYR C OH  1 
ATOM   6654  N N   . GLY C 1 176 ? -24.905 33.530  51.856 1.00 32.32  ? 378 GLY C N   1 
ATOM   6655  C CA  . GLY C 1 176 ? -26.262 33.896  51.504 1.00 32.49  ? 378 GLY C CA  1 
ATOM   6656  C C   . GLY C 1 176 ? -27.095 32.638  51.507 1.00 32.67  ? 378 GLY C C   1 
ATOM   6657  O O   . GLY C 1 176 ? -26.571 31.525  51.430 1.00 32.42  ? 378 GLY C O   1 
ATOM   6658  N N   . TYR C 1 177 ? -28.408 32.817  51.603 1.00 33.42  ? 379 TYR C N   1 
ATOM   6659  C CA  . TYR C 1 177 ? -29.288 31.662  51.666 1.00 33.80  ? 379 TYR C CA  1 
ATOM   6660  C C   . TYR C 1 177 ? -30.526 31.905  50.821 1.00 34.50  ? 379 TYR C C   1 
ATOM   6661  O O   . TYR C 1 177 ? -30.640 32.909  50.114 1.00 34.35  ? 379 TYR C O   1 
ATOM   6662  C CB  . TYR C 1 177 ? -29.677 31.328  53.109 1.00 34.40  ? 379 TYR C CB  1 
ATOM   6663  C CG  . TYR C 1 177 ? -30.435 32.419  53.821 1.00 35.12  ? 379 TYR C CG  1 
ATOM   6664  C CD1 . TYR C 1 177 ? -31.819 32.477  53.772 1.00 34.99  ? 379 TYR C CD1 1 
ATOM   6665  C CD2 . TYR C 1 177 ? -29.765 33.385  54.556 1.00 35.16  ? 379 TYR C CD2 1 
ATOM   6666  C CE1 . TYR C 1 177 ? -32.511 33.467  54.428 1.00 35.87  ? 379 TYR C CE1 1 
ATOM   6667  C CE2 . TYR C 1 177 ? -30.449 34.376  55.215 1.00 35.94  ? 379 TYR C CE2 1 
ATOM   6668  C CZ  . TYR C 1 177 ? -31.820 34.413  55.147 1.00 36.95  ? 379 TYR C CZ  1 
ATOM   6669  O OH  . TYR C 1 177 ? -32.506 35.403  55.804 1.00 38.10  ? 379 TYR C OH  1 
ATOM   6670  N N   . LEU C 1 178 ? -31.448 30.955  50.899 1.00 31.80  ? 380 LEU C N   1 
ATOM   6671  C CA  . LEU C 1 178 ? -32.691 30.972  50.151 1.00 32.82  ? 380 LEU C CA  1 
ATOM   6672  C C   . LEU C 1 178 ? -33.833 30.524  51.052 1.00 35.16  ? 380 LEU C C   1 
ATOM   6673  O O   . LEU C 1 178 ? -33.633 29.777  52.013 1.00 36.36  ? 380 LEU C O   1 
ATOM   6674  C CB  . LEU C 1 178 ? -32.607 30.058  48.925 1.00 34.63  ? 380 LEU C CB  1 
ATOM   6675  C CG  . LEU C 1 178 ? -31.589 30.432  47.849 1.00 35.01  ? 380 LEU C CG  1 
ATOM   6676  C CD1 . LEU C 1 178 ? -31.501 29.344  46.806 1.00 34.61  ? 380 LEU C CD1 1 
ATOM   6677  C CD2 . LEU C 1 178 ? -31.966 31.745  47.206 1.00 34.46  ? 380 LEU C CD2 1 
ATOM   6678  N N   . THR C 1 179 ? -35.035 30.992  50.736 1.00 36.54  ? 381 THR C N   1 
ATOM   6679  C CA  . THR C 1 179 ? -36.222 30.597  51.481 1.00 39.07  ? 381 THR C CA  1 
ATOM   6680  C C   . THR C 1 179 ? -37.377 30.399  50.510 1.00 39.29  ? 381 THR C C   1 
ATOM   6681  O O   . THR C 1 179 ? -37.165 30.393  49.295 1.00 39.19  ? 381 THR C O   1 
ATOM   6682  C CB  . THR C 1 179 ? -36.558 31.629  52.559 1.00 41.13  ? 381 THR C CB  1 
ATOM   6683  O OG1 . THR C 1 179 ? -37.642 31.151  53.364 1.00 42.84  ? 381 THR C OG1 1 
ATOM   6684  C CG2 . THR C 1 179 ? -36.927 32.957  51.939 1.00 43.04  ? 381 THR C CG2 1 
ATOM   6685  N N   . LEU C 1 180 ? -38.590 30.214  51.024 1.00 41.43  ? 382 LEU C N   1 
ATOM   6686  C CA  . LEU C 1 180 ? -39.713 29.857  50.168 1.00 41.93  ? 382 LEU C CA  1 
ATOM   6687  C C   . LEU C 1 180 ? -39.992 30.955  49.149 1.00 43.52  ? 382 LEU C C   1 
ATOM   6688  O O   . LEU C 1 180 ? -39.727 32.136  49.386 1.00 43.84  ? 382 LEU C O   1 
ATOM   6689  C CB  . LEU C 1 180 ? -40.961 29.599  51.005 1.00 42.78  ? 382 LEU C CB  1 
ATOM   6690  C CG  . LEU C 1 180 ? -40.888 28.437  51.992 1.00 42.24  ? 382 LEU C CG  1 
ATOM   6691  C CD1 . LEU C 1 180 ? -42.182 28.349  52.779 1.00 41.90  ? 382 LEU C CD1 1 
ATOM   6692  C CD2 . LEU C 1 180 ? -40.585 27.129  51.278 1.00 41.56  ? 382 LEU C CD2 1 
ATOM   6693  N N   . ASN C 1 181 ? -40.531 30.555  47.999 1.00 47.05  ? 383 ASN C N   1 
ATOM   6694  C CA  . ASN C 1 181 ? -40.839 31.501  46.940 1.00 49.12  ? 383 ASN C CA  1 
ATOM   6695  C C   . ASN C 1 181 ? -41.976 30.987  46.070 1.00 51.77  ? 383 ASN C C   1 
ATOM   6696  O O   . ASN C 1 181 ? -42.226 29.783  45.973 1.00 51.85  ? 383 ASN C O   1 
ATOM   6697  C CB  . ASN C 1 181 ? -39.626 31.779  46.052 1.00 47.29  ? 383 ASN C CB  1 
ATOM   6698  C CG  . ASN C 1 181 ? -39.133 30.540  45.334 1.00 47.62  ? 383 ASN C CG  1 
ATOM   6699  O OD1 . ASN C 1 181 ? -39.429 29.416  45.735 1.00 48.61  ? 383 ASN C OD1 1 
ATOM   6700  N ND2 . ASN C 1 181 ? -38.404 30.740  44.247 1.00 47.36  ? 383 ASN C ND2 1 
ATOM   6701  N N   . ASP C 1 182 ? -42.660 31.933  45.433 1.00 53.14  ? 384 ASP C N   1 
ATOM   6702  C CA  . ASP C 1 182 ? -43.563 31.665  44.319 1.00 55.75  ? 384 ASP C CA  1 
ATOM   6703  C C   . ASP C 1 182 ? -43.140 32.592  43.188 1.00 54.85  ? 384 ASP C C   1 
ATOM   6704  O O   . ASP C 1 182 ? -43.306 33.812  43.290 1.00 55.04  ? 384 ASP C O   1 
ATOM   6705  C CB  . ASP C 1 182 ? -45.022 31.896  44.715 1.00 58.38  ? 384 ASP C CB  1 
ATOM   6706  C CG  . ASP C 1 182 ? -45.986 31.614  43.582 1.00 62.70  ? 384 ASP C CG  1 
ATOM   6707  O OD1 . ASP C 1 182 ? -46.097 30.440  43.172 1.00 65.61  ? 384 ASP C OD1 1 
ATOM   6708  O OD2 . ASP C 1 182 ? -46.636 32.566  43.105 1.00 65.01  ? 384 ASP C OD2 1 
ATOM   6709  N N   . GLY C 1 183 ? -42.608 32.021  42.113 1.00 56.09  ? 385 GLY C N   1 
ATOM   6710  C CA  . GLY C 1 183 ? -41.953 32.850  41.114 1.00 55.15  ? 385 GLY C CA  1 
ATOM   6711  C C   . GLY C 1 183 ? -40.751 33.535  41.734 1.00 54.75  ? 385 GLY C C   1 
ATOM   6712  O O   . GLY C 1 183 ? -39.918 32.900  42.390 1.00 55.03  ? 385 GLY C O   1 
ATOM   6713  N N   . SER C 1 184 ? -40.646 34.845  41.530 1.00 49.97  ? 386 SER C N   1 
ATOM   6714  C CA  . SER C 1 184 ? -39.657 35.641  42.242 1.00 48.54  ? 386 SER C CA  1 
ATOM   6715  C C   . SER C 1 184 ? -40.225 36.316  43.483 1.00 47.96  ? 386 SER C C   1 
ATOM   6716  O O   . SER C 1 184 ? -39.481 37.000  44.193 1.00 48.13  ? 386 SER C O   1 
ATOM   6717  C CB  . SER C 1 184 ? -39.055 36.702  41.316 1.00 48.78  ? 386 SER C CB  1 
ATOM   6718  O OG  . SER C 1 184 ? -40.042 37.611  40.869 1.00 50.47  ? 386 SER C OG  1 
ATOM   6719  N N   . GLN C 1 185 ? -41.516 36.150  43.751 1.00 49.96  ? 387 GLN C N   1 
ATOM   6720  C CA  . GLN C 1 185 ? -42.131 36.713  44.940 1.00 49.40  ? 387 GLN C CA  1 
ATOM   6721  C C   . GLN C 1 185 ? -41.756 35.906  46.179 1.00 49.09  ? 387 GLN C C   1 
ATOM   6722  O O   . GLN C 1 185 ? -41.310 34.760  46.099 1.00 49.20  ? 387 GLN C O   1 
ATOM   6723  C CB  . GLN C 1 185 ? -43.652 36.755  44.798 1.00 51.09  ? 387 GLN C CB  1 
ATOM   6724  C CG  . GLN C 1 185 ? -44.167 37.710  43.741 1.00 52.51  ? 387 GLN C CG  1 
ATOM   6725  C CD  . GLN C 1 185 ? -45.677 37.670  43.615 1.00 54.27  ? 387 GLN C CD  1 
ATOM   6726  O OE1 . GLN C 1 185 ? -46.313 36.671  43.950 1.00 55.65  ? 387 GLN C OE1 1 
ATOM   6727  N NE2 . GLN C 1 185 ? -46.261 38.761  43.136 1.00 53.96  ? 387 GLN C NE2 1 
ATOM   6728  N N   . ALA C 1 186 ? -41.931 36.533  47.336 1.00 48.84  ? 388 ALA C N   1 
ATOM   6729  C CA  . ALA C 1 186 ? -41.861 35.849  48.614 1.00 47.93  ? 388 ALA C CA  1 
ATOM   6730  C C   . ALA C 1 186 ? -43.256 35.368  49.006 1.00 47.88  ? 388 ALA C C   1 
ATOM   6731  O O   . ALA C 1 186 ? -44.239 35.582  48.295 1.00 47.68  ? 388 ALA C O   1 
ATOM   6732  C CB  . ALA C 1 186 ? -41.268 36.766  49.683 1.00 44.67  ? 388 ALA C CB  1 
ATOM   6733  N N   . VAL C 1 187 ? -43.342 34.699  50.156 1.00 48.74  ? 389 VAL C N   1 
ATOM   6734  C CA  . VAL C 1 187 ? -44.613 34.255  50.711 1.00 49.51  ? 389 VAL C CA  1 
ATOM   6735  C C   . VAL C 1 187 ? -44.620 34.553  52.203 1.00 49.11  ? 389 VAL C C   1 
ATOM   6736  O O   . VAL C 1 187 ? -43.581 34.809  52.815 1.00 49.08  ? 389 VAL C O   1 
ATOM   6737  C CB  . VAL C 1 187 ? -44.887 32.756  50.464 1.00 47.10  ? 389 VAL C CB  1 
ATOM   6738  C CG1 . VAL C 1 187 ? -45.065 32.477  48.981 1.00 49.96  ? 389 VAL C CG1 1 
ATOM   6739  C CG2 . VAL C 1 187 ? -43.763 31.913  51.040 1.00 46.82  ? 389 VAL C CG2 1 
ATOM   6740  N N   . GLY C 1 188 ? -45.818 34.509  52.787 1.00 50.16  ? 390 GLY C N   1 
ATOM   6741  C CA  . GLY C 1 188 ? -45.968 34.822  54.196 1.00 49.42  ? 390 GLY C CA  1 
ATOM   6742  C C   . GLY C 1 188 ? -45.201 33.899  55.116 1.00 49.40  ? 390 GLY C C   1 
ATOM   6743  O O   . GLY C 1 188 ? -44.934 34.263  56.266 1.00 49.43  ? 390 GLY C O   1 
ATOM   6744  N N   . ARG C 1 189 ? -44.842 32.708  54.640 1.00 47.25  ? 391 ARG C N   1 
ATOM   6745  C CA  . ARG C 1 189 ? -44.097 31.755  55.447 1.00 46.26  ? 391 ARG C CA  1 
ATOM   6746  C C   . ARG C 1 189 ? -42.590 31.942  55.329 1.00 44.76  ? 391 ARG C C   1 
ATOM   6747  O O   . ARG C 1 189 ? -41.846 31.377  56.138 1.00 45.44  ? 391 ARG C O   1 
ATOM   6748  C CB  . ARG C 1 189 ? -44.496 30.329  55.047 1.00 44.60  ? 391 ARG C CB  1 
ATOM   6749  C CG  . ARG C 1 189 ? -43.903 29.228  55.907 1.00 48.38  ? 391 ARG C CG  1 
ATOM   6750  C CD  . ARG C 1 189 ? -44.501 27.869  55.588 1.00 51.66  ? 391 ARG C CD  1 
ATOM   6751  N NE  . ARG C 1 189 ? -45.912 27.769  55.954 1.00 55.70  ? 391 ARG C NE  1 
ATOM   6752  C CZ  . ARG C 1 189 ? -46.910 27.740  55.079 1.00 57.80  ? 391 ARG C CZ  1 
ATOM   6753  N NH1 . ARG C 1 189 ? -46.655 27.796  53.781 1.00 58.34  ? 391 ARG C NH1 1 
ATOM   6754  N NH2 . ARG C 1 189 ? -48.162 27.643  55.503 1.00 59.41  ? 391 ARG C NH2 1 
ATOM   6755  N N   . SER C 1 190 ? -42.126 32.741  54.371 1.00 46.60  ? 392 SER C N   1 
ATOM   6756  C CA  . SER C 1 190 ? -40.696 32.935  54.175 1.00 45.37  ? 392 SER C CA  1 
ATOM   6757  C C   . SER C 1 190 ? -40.054 33.546  55.413 1.00 45.37  ? 392 SER C C   1 
ATOM   6758  O O   . SER C 1 190 ? -40.689 34.279  56.175 1.00 44.82  ? 392 SER C O   1 
ATOM   6759  C CB  . SER C 1 190 ? -40.437 33.827  52.963 1.00 46.91  ? 392 SER C CB  1 
ATOM   6760  O OG  . SER C 1 190 ? -40.857 33.198  51.768 1.00 47.92  ? 392 SER C OG  1 
ATOM   6761  N N   . SER C 1 191 ? -38.779 33.234  55.612 1.00 44.76  ? 393 SER C N   1 
ATOM   6762  C CA  . SER C 1 191 ? -38.037 33.688  56.777 1.00 43.25  ? 393 SER C CA  1 
ATOM   6763  C C   . SER C 1 191 ? -36.897 34.606  56.363 1.00 42.62  ? 393 SER C C   1 
ATOM   6764  O O   . SER C 1 191 ? -36.325 34.459  55.279 1.00 43.04  ? 393 SER C O   1 
ATOM   6765  C CB  . SER C 1 191 ? -37.484 32.505  57.573 1.00 43.67  ? 393 SER C CB  1 
ATOM   6766  O OG  . SER C 1 191 ? -38.532 31.745  58.145 1.00 47.56  ? 393 SER C OG  1 
ATOM   6767  N N   . PHE C 1 192 ? -36.579 35.553  57.237 1.00 40.66  ? 394 PHE C N   1 
ATOM   6768  C CA  . PHE C 1 192 ? -35.451 36.455  57.078 1.00 39.61  ? 394 PHE C CA  1 
ATOM   6769  C C   . PHE C 1 192 ? -34.574 36.355  58.316 1.00 40.87  ? 394 PHE C C   1 
ATOM   6770  O O   . PHE C 1 192 ? -35.080 36.269  59.439 1.00 40.90  ? 394 PHE C O   1 
ATOM   6771  C CB  . PHE C 1 192 ? -35.925 37.897  56.863 1.00 38.75  ? 394 PHE C CB  1 
ATOM   6772  C CG  . PHE C 1 192 ? -34.814 38.903  56.812 1.00 38.20  ? 394 PHE C CG  1 
ATOM   6773  C CD1 . PHE C 1 192 ? -34.049 39.049  55.675 1.00 38.12  ? 394 PHE C CD1 1 
ATOM   6774  C CD2 . PHE C 1 192 ? -34.546 39.714  57.898 1.00 38.54  ? 394 PHE C CD2 1 
ATOM   6775  C CE1 . PHE C 1 192 ? -33.029 39.974  55.625 1.00 37.67  ? 394 PHE C CE1 1 
ATOM   6776  C CE2 . PHE C 1 192 ? -33.527 40.642  57.853 1.00 37.95  ? 394 PHE C CE2 1 
ATOM   6777  C CZ  . PHE C 1 192 ? -32.769 40.772  56.715 1.00 37.42  ? 394 PHE C CZ  1 
ATOM   6778  N N   . TYR C 1 193 ? -33.261 36.359  58.111 1.00 38.78  ? 395 TYR C N   1 
ATOM   6779  C CA  . TYR C 1 193 ? -32.304 36.169  59.190 1.00 39.52  ? 395 TYR C CA  1 
ATOM   6780  C C   . TYR C 1 193 ? -31.288 37.298  59.191 1.00 41.17  ? 395 TYR C C   1 
ATOM   6781  O O   . TYR C 1 193 ? -30.721 37.634  58.147 1.00 41.27  ? 395 TYR C O   1 
ATOM   6782  C CB  . TYR C 1 193 ? -31.596 34.823  59.061 1.00 35.99  ? 395 TYR C CB  1 
ATOM   6783  C CG  . TYR C 1 193 ? -32.532 33.658  59.213 1.00 37.19  ? 395 TYR C CG  1 
ATOM   6784  C CD1 . TYR C 1 193 ? -32.828 33.144  60.464 1.00 38.20  ? 395 TYR C CD1 1 
ATOM   6785  C CD2 . TYR C 1 193 ? -33.133 33.081  58.109 1.00 38.35  ? 395 TYR C CD2 1 
ATOM   6786  C CE1 . TYR C 1 193 ? -33.690 32.081  60.612 1.00 40.03  ? 395 TYR C CE1 1 
ATOM   6787  C CE2 . TYR C 1 193 ? -33.996 32.017  58.244 1.00 40.76  ? 395 TYR C CE2 1 
ATOM   6788  C CZ  . TYR C 1 193 ? -34.272 31.521  59.498 1.00 41.19  ? 395 TYR C CZ  1 
ATOM   6789  O OH  . TYR C 1 193 ? -35.134 30.461  59.637 1.00 42.78  ? 395 TYR C OH  1 
ATOM   6790  N N   . CYS C 1 194 ? -31.069 37.880  60.364 1.00 41.96  ? 396 CYS C N   1 
ATOM   6791  C CA  . CYS C 1 194 ? -30.031 38.876  60.573 1.00 43.16  ? 396 CYS C CA  1 
ATOM   6792  C C   . CYS C 1 194 ? -28.983 38.275  61.499 1.00 42.54  ? 396 CYS C C   1 
ATOM   6793  O O   . CYS C 1 194 ? -29.255 38.040  62.680 1.00 43.18  ? 396 CYS C O   1 
ATOM   6794  C CB  . CYS C 1 194 ? -30.613 40.159  61.164 1.00 39.50  ? 396 CYS C CB  1 
ATOM   6795  S SG  . CYS C 1 194 ? -29.434 41.511  61.346 1.00 47.70  ? 396 CYS C SG  1 
ATOM   6796  N N   . LEU C 1 195 ? -27.794 38.017  60.961 1.00 39.74  ? 397 LEU C N   1 
ATOM   6797  C CA  . LEU C 1 195 ? -26.748 37.359  61.730 1.00 40.06  ? 397 LEU C CA  1 
ATOM   6798  C C   . LEU C 1 195 ? -26.148 38.271  62.791 1.00 41.63  ? 397 LEU C C   1 
ATOM   6799  O O   . LEU C 1 195 ? -25.362 37.803  63.622 1.00 41.96  ? 397 LEU C O   1 
ATOM   6800  C CB  . LEU C 1 195 ? -25.658 36.847  60.788 1.00 39.47  ? 397 LEU C CB  1 
ATOM   6801  C CG  . LEU C 1 195 ? -25.900 35.509  60.082 1.00 37.58  ? 397 LEU C CG  1 
ATOM   6802  C CD1 . LEU C 1 195 ? -27.050 35.584  59.094 1.00 35.51  ? 397 LEU C CD1 1 
ATOM   6803  C CD2 . LEU C 1 195 ? -24.645 35.062  59.376 1.00 37.24  ? 397 LEU C CD2 1 
ATOM   6804  N N   . GLU C 1 196 ? -26.501 39.559  62.778 1.00 45.72  ? 398 GLU C N   1 
ATOM   6805  C CA  . GLU C 1 196 ? -26.185 40.458  63.881 1.00 47.18  ? 398 GLU C CA  1 
ATOM   6806  C C   . GLU C 1 196 ? -26.935 40.091  65.150 1.00 46.80  ? 398 GLU C C   1 
ATOM   6807  O O   . GLU C 1 196 ? -26.565 40.562  66.230 1.00 47.27  ? 398 GLU C O   1 
ATOM   6808  C CB  . GLU C 1 196 ? -26.543 41.898  63.508 1.00 39.09  ? 398 GLU C CB  1 
ATOM   6809  C CG  . GLU C 1 196 ? -25.828 42.455  62.292 1.00 46.08  ? 398 GLU C CG  1 
ATOM   6810  C CD  . GLU C 1 196 ? -24.331 42.461  62.443 1.00 50.47  ? 398 GLU C CD  1 
ATOM   6811  O OE1 . GLU C 1 196 ? -23.847 42.720  63.563 1.00 54.11  ? 398 GLU C OE1 1 
ATOM   6812  O OE2 . GLU C 1 196 ? -23.639 42.218  61.436 1.00 51.38  ? 398 GLU C OE2 1 
ATOM   6813  N N   . TYR C 1 197 ? -27.980 39.276  65.041 1.00 47.98  ? 399 TYR C N   1 
ATOM   6814  C CA  . TYR C 1 197 ? -28.890 38.976  66.135 1.00 47.73  ? 399 TYR C CA  1 
ATOM   6815  C C   . TYR C 1 197 ? -28.410 37.808  66.991 1.00 46.40  ? 399 TYR C C   1 
ATOM   6816  O O   . TYR C 1 197 ? -29.057 37.471  67.987 1.00 45.99  ? 399 TYR C O   1 
ATOM   6817  C CB  . TYR C 1 197 ? -30.286 38.717  65.557 1.00 48.98  ? 399 TYR C CB  1 
ATOM   6818  C CG  . TYR C 1 197 ? -31.387 38.437  66.551 1.00 52.36  ? 399 TYR C CG  1 
ATOM   6819  C CD1 . TYR C 1 197 ? -31.927 39.454  67.323 1.00 53.10  ? 399 TYR C CD1 1 
ATOM   6820  C CD2 . TYR C 1 197 ? -31.921 37.164  66.678 1.00 53.45  ? 399 TYR C CD2 1 
ATOM   6821  C CE1 . TYR C 1 197 ? -32.944 39.201  68.221 1.00 54.93  ? 399 TYR C CE1 1 
ATOM   6822  C CE2 . TYR C 1 197 ? -32.939 36.904  67.570 1.00 55.60  ? 399 TYR C CE2 1 
ATOM   6823  C CZ  . TYR C 1 197 ? -33.447 37.925  68.338 1.00 56.82  ? 399 TYR C CZ  1 
ATOM   6824  O OH  . TYR C 1 197 ? -34.463 37.667  69.227 1.00 60.16  ? 399 TYR C OH  1 
ATOM   6825  N N   . PHE C 1 198 ? -27.273 37.180  66.622 1.00 46.71  ? 400 PHE C N   1 
ATOM   6826  C CA  . PHE C 1 198 ? -26.488 36.197  67.353 1.00 45.80  ? 400 PHE C CA  1 
ATOM   6827  C C   . PHE C 1 198 ? -25.408 36.885  68.179 1.00 45.58  ? 400 PHE C C   1 
ATOM   6828  O O   . PHE C 1 198 ? -24.896 37.938  67.789 1.00 47.11  ? 400 PHE C O   1 
ATOM   6829  C CB  . PHE C 1 198 ? -25.826 35.218  66.391 1.00 44.06  ? 400 PHE C CB  1 
ATOM   6830  C CG  . PHE C 1 198 ? -26.789 34.378  65.624 1.00 43.53  ? 400 PHE C CG  1 
ATOM   6831  C CD1 . PHE C 1 198 ? -27.271 33.200  66.155 1.00 43.25  ? 400 PHE C CD1 1 
ATOM   6832  C CD2 . PHE C 1 198 ? -27.220 34.768  64.374 1.00 43.23  ? 400 PHE C CD2 1 
ATOM   6833  C CE1 . PHE C 1 198 ? -28.160 32.424  65.451 1.00 44.30  ? 400 PHE C CE1 1 
ATOM   6834  C CE2 . PHE C 1 198 ? -28.111 33.998  63.668 1.00 44.08  ? 400 PHE C CE2 1 
ATOM   6835  C CZ  . PHE C 1 198 ? -28.583 32.823  64.207 1.00 45.04  ? 400 PHE C CZ  1 
ATOM   6836  N N   . PRO C 1 199 ? -25.031 36.313  69.318 1.00 47.03  ? 401 PRO C N   1 
ATOM   6837  C CA  . PRO C 1 199 ? -23.818 36.779  69.994 1.00 46.55  ? 401 PRO C CA  1 
ATOM   6838  C C   . PRO C 1 199 ? -22.586 36.349  69.214 1.00 45.87  ? 401 PRO C C   1 
ATOM   6839  O O   . PRO C 1 199 ? -22.530 35.243  68.670 1.00 45.64  ? 401 PRO C O   1 
ATOM   6840  C CB  . PRO C 1 199 ? -23.891 36.098  71.364 1.00 45.00  ? 401 PRO C CB  1 
ATOM   6841  C CG  . PRO C 1 199 ? -24.702 34.876  71.122 1.00 45.20  ? 401 PRO C CG  1 
ATOM   6842  C CD  . PRO C 1 199 ? -25.715 35.254  70.078 1.00 46.52  ? 401 PRO C CD  1 
ATOM   6843  N N   . SER C 1 200 ? -21.597 37.236  69.153 1.00 45.16  ? 402 SER C N   1 
ATOM   6844  C CA  . SER C 1 200 ? -20.404 36.994  68.357 1.00 44.47  ? 402 SER C CA  1 
ATOM   6845  C C   . SER C 1 200 ? -19.169 37.410  69.140 1.00 43.44  ? 402 SER C C   1 
ATOM   6846  O O   . SER C 1 200 ? -19.254 38.071  70.177 1.00 43.68  ? 402 SER C O   1 
ATOM   6847  C CB  . SER C 1 200 ? -20.449 37.746  67.023 1.00 43.44  ? 402 SER C CB  1 
ATOM   6848  O OG  . SER C 1 200 ? -20.439 39.145  67.232 1.00 45.05  ? 402 SER C OG  1 
ATOM   6849  N N   . GLN C 1 201 ? -18.012 37.005  68.625 1.00 43.26  ? 403 GLN C N   1 
ATOM   6850  C CA  . GLN C 1 201 ? -16.729 37.336  69.226 1.00 43.03  ? 403 GLN C CA  1 
ATOM   6851  C C   . GLN C 1 201 ? -15.962 38.302  68.333 1.00 42.86  ? 403 GLN C C   1 
ATOM   6852  O O   . GLN C 1 201 ? -15.802 38.064  67.133 1.00 43.30  ? 403 GLN C O   1 
ATOM   6853  C CB  . GLN C 1 201 ? -15.906 36.069  69.457 1.00 39.52  ? 403 GLN C CB  1 
ATOM   6854  C CG  . GLN C 1 201 ? -14.600 36.305  70.180 1.00 45.28  ? 403 GLN C CG  1 
ATOM   6855  C CD  . GLN C 1 201 ? -13.879 35.016  70.496 1.00 47.71  ? 403 GLN C CD  1 
ATOM   6856  O OE1 . GLN C 1 201 ? -14.399 33.929  70.259 1.00 48.88  ? 403 GLN C OE1 1 
ATOM   6857  N NE2 . GLN C 1 201 ? -12.673 35.130  71.035 1.00 48.67  ? 403 GLN C NE2 1 
ATOM   6858  N N   . MET C 1 202 ? -15.489 39.393  68.926 1.00 45.15  ? 404 MET C N   1 
ATOM   6859  C CA  . MET C 1 202 ? -14.770 40.438  68.211 1.00 44.78  ? 404 MET C CA  1 
ATOM   6860  C C   . MET C 1 202 ? -13.274 40.226  68.401 1.00 44.56  ? 404 MET C C   1 
ATOM   6861  O O   . MET C 1 202 ? -12.834 39.840  69.489 1.00 45.98  ? 404 MET C O   1 
ATOM   6862  C CB  . MET C 1 202 ? -15.193 41.819  68.711 1.00 46.17  ? 404 MET C CB  1 
ATOM   6863  C CG  . MET C 1 202 ? -16.657 42.135  68.443 1.00 48.41  ? 404 MET C CG  1 
ATOM   6864  S SD  . MET C 1 202 ? -17.211 43.706  69.133 1.00 52.07  ? 404 MET C SD  1 
ATOM   6865  C CE  . MET C 1 202 ? -16.394 44.872  68.050 1.00 50.60  ? 404 MET C CE  1 
ATOM   6866  N N   . LEU C 1 203 ? -12.499 40.465  67.344 1.00 44.68  ? 405 LEU C N   1 
ATOM   6867  C CA  . LEU C 1 203 ? -11.072 40.158  67.328 1.00 44.58  ? 405 LEU C CA  1 
ATOM   6868  C C   . LEU C 1 203 ? -10.283 41.341  66.787 1.00 44.87  ? 405 LEU C C   1 
ATOM   6869  O O   . LEU C 1 203 ? -10.493 41.761  65.646 1.00 45.14  ? 405 LEU C O   1 
ATOM   6870  C CB  . LEU C 1 203 ? -10.777 38.921  66.474 1.00 44.58  ? 405 LEU C CB  1 
ATOM   6871  C CG  . LEU C 1 203 ? -10.866 37.515  67.065 1.00 42.50  ? 405 LEU C CG  1 
ATOM   6872  C CD1 . LEU C 1 203 ? -12.289 37.148  67.421 1.00 40.54  ? 405 LEU C CD1 1 
ATOM   6873  C CD2 . LEU C 1 203 ? -10.281 36.508  66.089 1.00 41.85  ? 405 LEU C CD2 1 
ATOM   6874  N N   . ARG C 1 204 ? -9.357  41.852  67.592 1.00 46.66  ? 406 ARG C N   1 
ATOM   6875  C CA  . ARG C 1 204 ? -8.361  42.787  67.104 1.00 48.44  ? 406 ARG C CA  1 
ATOM   6876  C C   . ARG C 1 204 ? -7.104  42.022  66.692 1.00 49.93  ? 406 ARG C C   1 
ATOM   6877  O O   . ARG C 1 204 ? -7.055  40.792  66.731 1.00 49.89  ? 406 ARG C O   1 
ATOM   6878  C CB  . ARG C 1 204 ? -8.067  43.862  68.151 1.00 47.57  ? 406 ARG C CB  1 
ATOM   6879  C CG  . ARG C 1 204 ? -9.216  44.846  68.334 1.00 47.40  ? 406 ARG C CG  1 
ATOM   6880  C CD  . ARG C 1 204 ? -8.880  45.963  69.305 1.00 47.14  ? 406 ARG C CD  1 
ATOM   6881  N NE  . ARG C 1 204 ? -9.974  46.924  69.414 1.00 51.25  ? 406 ARG C NE  1 
ATOM   6882  C CZ  . ARG C 1 204 ? -9.980  47.960  70.245 1.00 51.90  ? 406 ARG C CZ  1 
ATOM   6883  N NH1 . ARG C 1 204 ? -8.949  48.172  71.048 1.00 52.64  ? 406 ARG C NH1 1 
ATOM   6884  N NH2 . ARG C 1 204 ? -11.017 48.784  70.276 1.00 52.07  ? 406 ARG C NH2 1 
ATOM   6885  N N   . THR C 1 205 ? -6.068  42.763  66.296 1.00 45.86  ? 407 THR C N   1 
ATOM   6886  C CA  . THR C 1 205 ? -4.916  42.156  65.638 1.00 47.41  ? 407 THR C CA  1 
ATOM   6887  C C   . THR C 1 205 ? -4.196  41.130  66.506 1.00 48.47  ? 407 THR C C   1 
ATOM   6888  O O   . THR C 1 205 ? -3.454  40.302  65.968 1.00 53.74  ? 407 THR C O   1 
ATOM   6889  C CB  . THR C 1 205 ? -3.934  43.240  65.198 1.00 48.83  ? 407 THR C CB  1 
ATOM   6890  O OG1 . THR C 1 205 ? -2.919  42.653  64.377 1.00 52.15  ? 407 THR C OG1 1 
ATOM   6891  C CG2 . THR C 1 205 ? -3.287  43.899  66.403 1.00 47.70  ? 407 THR C CG2 1 
ATOM   6892  N N   . GLY C 1 206 ? -4.395  41.156  67.823 1.00 49.81  ? 408 GLY C N   1 
ATOM   6893  C CA  . GLY C 1 206 ? -3.768  40.188  68.700 1.00 49.74  ? 408 GLY C CA  1 
ATOM   6894  C C   . GLY C 1 206 ? -4.654  39.060  69.171 1.00 48.32  ? 408 GLY C C   1 
ATOM   6895  O O   . GLY C 1 206 ? -4.155  38.090  69.748 1.00 49.20  ? 408 GLY C O   1 
ATOM   6896  N N   . ASN C 1 207 ? -5.961  39.168  68.953 1.00 46.60  ? 409 ASN C N   1 
ATOM   6897  C CA  . ASN C 1 207 ? -6.917  38.159  69.378 1.00 45.50  ? 409 ASN C CA  1 
ATOM   6898  C C   . ASN C 1 207 ? -6.928  36.968  68.422 1.00 45.00  ? 409 ASN C C   1 
ATOM   6899  O O   . ASN C 1 207 ? -6.486  37.052  67.274 1.00 45.25  ? 409 ASN C O   1 
ATOM   6900  C CB  . ASN C 1 207 ? -8.316  38.761  69.484 1.00 44.24  ? 409 ASN C CB  1 
ATOM   6901  C CG  . ASN C 1 207 ? -8.400  39.843  70.534 1.00 44.37  ? 409 ASN C CG  1 
ATOM   6902  O OD1 . ASN C 1 207 ? -8.923  40.926  70.285 1.00 45.49  ? 409 ASN C OD1 1 
ATOM   6903  N ND2 . ASN C 1 207 ? -7.878  39.557  71.717 1.00 45.15  ? 409 ASN C ND2 1 
ATOM   6904  N N   . ASN C 1 208 ? -7.435  35.843  68.922 1.00 42.95  ? 410 ASN C N   1 
ATOM   6905  C CA  . ASN C 1 208 ? -7.587  34.621  68.144 1.00 42.62  ? 410 ASN C CA  1 
ATOM   6906  C C   . ASN C 1 208 ? -8.919  33.955  68.474 1.00 42.72  ? 410 ASN C C   1 
ATOM   6907  O O   . ASN C 1 208 ? -9.600  34.313  69.438 1.00 42.96  ? 410 ASN C O   1 
ATOM   6908  C CB  . ASN C 1 208 ? -6.410  33.661  68.382 1.00 40.91  ? 410 ASN C CB  1 
ATOM   6909  C CG  . ASN C 1 208 ? -6.243  33.274  69.840 1.00 41.88  ? 410 ASN C CG  1 
ATOM   6910  O OD1 . ASN C 1 208 ? -7.210  33.162  70.589 1.00 44.90  ? 410 ASN C OD1 1 
ATOM   6911  N ND2 . ASN C 1 208 ? -5.000  33.069  70.250 1.00 42.38  ? 410 ASN C ND2 1 
ATOM   6912  N N   . PHE C 1 209 ? -9.287  32.970  67.658 1.00 37.53  ? 411 PHE C N   1 
ATOM   6913  C CA  . PHE C 1 209 ? -10.561 32.276  67.789 1.00 38.39  ? 411 PHE C CA  1 
ATOM   6914  C C   . PHE C 1 209 ? -10.354 30.778  67.617 1.00 38.83  ? 411 PHE C C   1 
ATOM   6915  O O   . PHE C 1 209 ? -9.528  30.352  66.807 1.00 39.36  ? 411 PHE C O   1 
ATOM   6916  C CB  . PHE C 1 209 ? -11.570 32.805  66.758 1.00 38.65  ? 411 PHE C CB  1 
ATOM   6917  C CG  . PHE C 1 209 ? -12.865 32.047  66.719 1.00 39.35  ? 411 PHE C CG  1 
ATOM   6918  C CD1 . PHE C 1 209 ? -13.840 32.260  67.675 1.00 39.87  ? 411 PHE C CD1 1 
ATOM   6919  C CD2 . PHE C 1 209 ? -13.116 31.141  65.705 1.00 39.03  ? 411 PHE C CD2 1 
ATOM   6920  C CE1 . PHE C 1 209 ? -15.032 31.567  67.632 1.00 39.06  ? 411 PHE C CE1 1 
ATOM   6921  C CE2 . PHE C 1 209 ? -14.303 30.448  65.656 1.00 39.59  ? 411 PHE C CE2 1 
ATOM   6922  C CZ  . PHE C 1 209 ? -15.264 30.661  66.620 1.00 38.97  ? 411 PHE C CZ  1 
ATOM   6923  N N   . GLN C 1 210 ? -11.098 29.981  68.386 1.00 36.80  ? 412 GLN C N   1 
ATOM   6924  C CA  . GLN C 1 210 ? -11.051 28.532  68.241 1.00 39.39  ? 412 GLN C CA  1 
ATOM   6925  C C   . GLN C 1 210 ? -12.328 27.910  68.786 1.00 38.51  ? 412 GLN C C   1 
ATOM   6926  O O   . GLN C 1 210 ? -13.048 28.517  69.583 1.00 39.43  ? 412 GLN C O   1 
ATOM   6927  C CB  . GLN C 1 210 ? -9.850  27.914  68.964 1.00 35.66  ? 412 GLN C CB  1 
ATOM   6928  C CG  . GLN C 1 210 ? -9.925  28.014  70.474 1.00 44.22  ? 412 GLN C CG  1 
ATOM   6929  C CD  . GLN C 1 210 ? -8.773  27.309  71.157 1.00 51.86  ? 412 GLN C CD  1 
ATOM   6930  O OE1 . GLN C 1 210 ? -7.740  27.045  70.542 1.00 54.72  ? 412 GLN C OE1 1 
ATOM   6931  N NE2 . GLN C 1 210 ? -8.945  26.995  72.436 1.00 53.26  ? 412 GLN C NE2 1 
ATOM   6932  N N   . PHE C 1 211 ? -12.599 26.682  68.345 1.00 35.65  ? 413 PHE C N   1 
ATOM   6933  C CA  . PHE C 1 211 ? -13.635 25.858  68.954 1.00 34.77  ? 413 PHE C CA  1 
ATOM   6934  C C   . PHE C 1 211 ? -13.360 24.401  68.607 1.00 34.42  ? 413 PHE C C   1 
ATOM   6935  O O   . PHE C 1 211 ? -12.660 24.099  67.639 1.00 33.57  ? 413 PHE C O   1 
ATOM   6936  C CB  . PHE C 1 211 ? -15.036 26.265  68.488 1.00 33.05  ? 413 PHE C CB  1 
ATOM   6937  C CG  . PHE C 1 211 ? -15.286 26.007  67.037 1.00 33.63  ? 413 PHE C CG  1 
ATOM   6938  C CD1 . PHE C 1 211 ? -15.859 24.816  66.626 1.00 34.46  ? 413 PHE C CD1 1 
ATOM   6939  C CD2 . PHE C 1 211 ? -14.927 26.936  66.081 1.00 34.50  ? 413 PHE C CD2 1 
ATOM   6940  C CE1 . PHE C 1 211 ? -16.083 24.566  65.299 1.00 34.33  ? 413 PHE C CE1 1 
ATOM   6941  C CE2 . PHE C 1 211 ? -15.151 26.688  64.749 1.00 35.37  ? 413 PHE C CE2 1 
ATOM   6942  C CZ  . PHE C 1 211 ? -15.730 25.499  64.359 1.00 35.32  ? 413 PHE C CZ  1 
ATOM   6943  N N   . SER C 1 212 ? -13.940 23.502  69.398 1.00 32.65  ? 414 SER C N   1 
ATOM   6944  C CA  . SER C 1 212 ? -13.824 22.071  69.168 1.00 32.35  ? 414 SER C CA  1 
ATOM   6945  C C   . SER C 1 212 ? -15.207 21.475  68.940 1.00 31.97  ? 414 SER C C   1 
ATOM   6946  O O   . SER C 1 212 ? -16.196 21.900  69.540 1.00 32.08  ? 414 SER C O   1 
ATOM   6947  C CB  . SER C 1 212 ? -13.128 21.363  70.339 1.00 30.45  ? 414 SER C CB  1 
ATOM   6948  O OG  . SER C 1 212 ? -13.890 21.470  71.528 1.00 35.27  ? 414 SER C OG  1 
ATOM   6949  N N   . TYR C 1 213 ? -15.263 20.479  68.059 1.00 28.67  ? 415 TYR C N   1 
ATOM   6950  C CA  . TYR C 1 213 ? -16.516 19.850  67.670 1.00 28.97  ? 415 TYR C CA  1 
ATOM   6951  C C   . TYR C 1 213 ? -16.383 18.338  67.757 1.00 30.88  ? 415 TYR C C   1 
ATOM   6952  O O   . TYR C 1 213 ? -15.335 17.772  67.441 1.00 30.80  ? 415 TYR C O   1 
ATOM   6953  C CB  . TYR C 1 213 ? -16.928 20.260  66.254 1.00 30.91  ? 415 TYR C CB  1 
ATOM   6954  C CG  . TYR C 1 213 ? -18.145 19.531  65.744 1.00 31.24  ? 415 TYR C CG  1 
ATOM   6955  C CD1 . TYR C 1 213 ? -19.412 19.867  66.189 1.00 29.59  ? 415 TYR C CD1 1 
ATOM   6956  C CD2 . TYR C 1 213 ? -18.025 18.510  64.814 1.00 32.18  ? 415 TYR C CD2 1 
ATOM   6957  C CE1 . TYR C 1 213 ? -20.521 19.207  65.729 1.00 31.37  ? 415 TYR C CE1 1 
ATOM   6958  C CE2 . TYR C 1 213 ? -19.129 17.845  64.348 1.00 32.12  ? 415 TYR C CE2 1 
ATOM   6959  C CZ  . TYR C 1 213 ? -20.374 18.198  64.808 1.00 32.57  ? 415 TYR C CZ  1 
ATOM   6960  O OH  . TYR C 1 213 ? -21.478 17.535  64.343 1.00 34.99  ? 415 TYR C OH  1 
ATOM   6961  N N   . GLU C 1 214 ? -17.459 17.688  68.190 1.00 30.95  ? 416 GLU C N   1 
ATOM   6962  C CA  . GLU C 1 214 ? -17.499 16.242  68.366 1.00 33.57  ? 416 GLU C CA  1 
ATOM   6963  C C   . GLU C 1 214 ? -18.503 15.646  67.387 1.00 32.30  ? 416 GLU C C   1 
ATOM   6964  O O   . GLU C 1 214 ? -19.713 15.843  67.540 1.00 32.96  ? 416 GLU C O   1 
ATOM   6965  C CB  . GLU C 1 214 ? -17.873 15.885  69.805 1.00 26.97  ? 416 GLU C CB  1 
ATOM   6966  C CG  . GLU C 1 214 ? -17.863 14.400  70.118 1.00 38.57  ? 416 GLU C CG  1 
ATOM   6967  C CD  . GLU C 1 214 ? -16.472 13.803  70.109 1.00 44.90  ? 416 GLU C CD  1 
ATOM   6968  O OE1 . GLU C 1 214 ? -15.493 14.574  70.141 1.00 46.72  ? 416 GLU C OE1 1 
ATOM   6969  O OE2 . GLU C 1 214 ? -16.357 12.560  70.072 1.00 49.05  ? 416 GLU C OE2 1 
ATOM   6970  N N   . PHE C 1 215 ? -18.001 14.919  66.390 1.00 31.40  ? 417 PHE C N   1 
ATOM   6971  C CA  . PHE C 1 215 ? -18.877 14.249  65.437 1.00 31.33  ? 417 PHE C CA  1 
ATOM   6972  C C   . PHE C 1 215 ? -19.747 13.216  66.139 1.00 34.09  ? 417 PHE C C   1 
ATOM   6973  O O   . PHE C 1 215 ? -19.299 12.520  67.052 1.00 33.66  ? 417 PHE C O   1 
ATOM   6974  C CB  . PHE C 1 215 ? -18.056 13.562  64.346 1.00 31.13  ? 417 PHE C CB  1 
ATOM   6975  C CG  . PHE C 1 215 ? -17.395 14.504  63.386 1.00 28.13  ? 417 PHE C CG  1 
ATOM   6976  C CD1 . PHE C 1 215 ? -18.052 14.916  62.244 1.00 26.57  ? 417 PHE C CD1 1 
ATOM   6977  C CD2 . PHE C 1 215 ? -16.117 14.968  63.618 1.00 27.33  ? 417 PHE C CD2 1 
ATOM   6978  C CE1 . PHE C 1 215 ? -17.449 15.766  61.353 1.00 25.49  ? 417 PHE C CE1 1 
ATOM   6979  C CE2 . PHE C 1 215 ? -15.512 15.826  62.730 1.00 25.79  ? 417 PHE C CE2 1 
ATOM   6980  C CZ  . PHE C 1 215 ? -16.180 16.227  61.598 1.00 25.60  ? 417 PHE C CZ  1 
ATOM   6981  N N   . GLU C 1 216 ? -20.998 13.117  65.705 1.00 30.97  ? 418 GLU C N   1 
ATOM   6982  C CA  . GLU C 1 216 ? -21.862 12.063  66.202 1.00 35.05  ? 418 GLU C CA  1 
ATOM   6983  C C   . GLU C 1 216 ? -21.521 10.746  65.513 1.00 35.10  ? 418 GLU C C   1 
ATOM   6984  O O   . GLU C 1 216 ? -20.975 10.717  64.408 1.00 34.69  ? 418 GLU C O   1 
ATOM   6985  C CB  . GLU C 1 216 ? -23.334 12.412  65.985 1.00 30.09  ? 418 GLU C CB  1 
ATOM   6986  C CG  . GLU C 1 216 ? -23.750 12.513  64.533 1.00 37.34  ? 418 GLU C CG  1 
ATOM   6987  C CD  . GLU C 1 216 ? -25.183 12.969  64.377 1.00 42.39  ? 418 GLU C CD  1 
ATOM   6988  O OE1 . GLU C 1 216 ? -25.933 12.924  65.373 1.00 45.76  ? 418 GLU C OE1 1 
ATOM   6989  O OE2 . GLU C 1 216 ? -25.567 13.363  63.257 1.00 44.15  ? 418 GLU C OE2 1 
ATOM   6990  N N   . ASN C 1 217 ? -21.846 9.647   66.188 1.00 34.31  ? 419 ASN C N   1 
ATOM   6991  C CA  . ASN C 1 217 ? -21.481 8.332   65.682 1.00 35.48  ? 419 ASN C CA  1 
ATOM   6992  C C   . ASN C 1 217 ? -22.125 8.073   64.326 1.00 34.25  ? 419 ASN C C   1 
ATOM   6993  O O   . ASN C 1 217 ? -23.346 8.161   64.172 1.00 34.80  ? 419 ASN C O   1 
ATOM   6994  C CB  . ASN C 1 217 ? -21.896 7.253   66.679 1.00 31.82  ? 419 ASN C CB  1 
ATOM   6995  C CG  . ASN C 1 217 ? -21.343 5.893   66.322 1.00 37.22  ? 419 ASN C CG  1 
ATOM   6996  O OD1 . ASN C 1 217 ? -20.274 5.783   65.725 1.00 40.20  ? 419 ASN C OD1 1 
ATOM   6997  N ND2 . ASN C 1 217 ? -22.070 4.845   66.685 1.00 39.56  ? 419 ASN C ND2 1 
ATOM   6998  N N   . VAL C 1 218 ? -21.291 7.747   63.345 1.00 33.18  ? 420 VAL C N   1 
ATOM   6999  C CA  . VAL C 1 218 ? -21.746 7.442   61.991 1.00 31.65  ? 420 VAL C CA  1 
ATOM   7000  C C   . VAL C 1 218 ? -21.155 6.098   61.593 1.00 30.29  ? 420 VAL C C   1 
ATOM   7001  O O   . VAL C 1 218 ? -20.155 5.649   62.174 1.00 30.29  ? 420 VAL C O   1 
ATOM   7002  C CB  . VAL C 1 218 ? -21.337 8.547   60.988 1.00 27.65  ? 420 VAL C CB  1 
ATOM   7003  C CG1 . VAL C 1 218 ? -22.025 9.854   61.327 1.00 30.62  ? 420 VAL C CG1 1 
ATOM   7004  C CG2 . VAL C 1 218 ? -19.834 8.724   60.981 1.00 28.79  ? 420 VAL C CG2 1 
ATOM   7005  N N   . PRO C 1 219 ? -21.759 5.419   60.622 1.00 27.70  ? 421 PRO C N   1 
ATOM   7006  C CA  . PRO C 1 219 ? -21.160 4.176   60.133 1.00 26.42  ? 421 PRO C CA  1 
ATOM   7007  C C   . PRO C 1 219 ? -19.900 4.458   59.336 1.00 25.68  ? 421 PRO C C   1 
ATOM   7008  O O   . PRO C 1 219 ? -19.777 5.486   58.667 1.00 26.29  ? 421 PRO C O   1 
ATOM   7009  C CB  . PRO C 1 219 ? -22.258 3.578   59.250 1.00 25.19  ? 421 PRO C CB  1 
ATOM   7010  C CG  . PRO C 1 219 ? -23.045 4.749   58.804 1.00 25.76  ? 421 PRO C CG  1 
ATOM   7011  C CD  . PRO C 1 219 ? -23.049 5.694   59.968 1.00 25.47  ? 421 PRO C CD  1 
ATOM   7012  N N   . PHE C 1 220 ? -18.946 3.535   59.434 1.00 24.30  ? 422 PHE C N   1 
ATOM   7013  C CA  . PHE C 1 220 ? -17.740 3.627   58.624 1.00 22.32  ? 422 PHE C CA  1 
ATOM   7014  C C   . PHE C 1 220 ? -18.103 3.668   57.149 1.00 21.99  ? 422 PHE C C   1 
ATOM   7015  O O   . PHE C 1 220 ? -18.903 2.861   56.670 1.00 21.93  ? 422 PHE C O   1 
ATOM   7016  C CB  . PHE C 1 220 ? -16.821 2.434   58.887 1.00 23.28  ? 422 PHE C CB  1 
ATOM   7017  C CG  . PHE C 1 220 ? -16.230 2.405   60.263 1.00 24.93  ? 422 PHE C CG  1 
ATOM   7018  C CD1 . PHE C 1 220 ? -15.049 3.067   60.537 1.00 24.89  ? 422 PHE C CD1 1 
ATOM   7019  C CD2 . PHE C 1 220 ? -16.850 1.707   61.281 1.00 24.96  ? 422 PHE C CD2 1 
ATOM   7020  C CE1 . PHE C 1 220 ? -14.500 3.036   61.799 1.00 24.73  ? 422 PHE C CE1 1 
ATOM   7021  C CE2 . PHE C 1 220 ? -16.305 1.676   62.547 1.00 24.12  ? 422 PHE C CE2 1 
ATOM   7022  C CZ  . PHE C 1 220 ? -15.127 2.341   62.804 1.00 24.38  ? 422 PHE C CZ  1 
ATOM   7023  N N   . HIS C 1 221 ? -17.527 4.622   56.426 1.00 20.37  ? 423 HIS C N   1 
ATOM   7024  C CA  . HIS C 1 221 ? -17.593 4.558   54.978 1.00 20.51  ? 423 HIS C CA  1 
ATOM   7025  C C   . HIS C 1 221 ? -16.913 3.285   54.518 1.00 21.20  ? 423 HIS C C   1 
ATOM   7026  O O   . HIS C 1 221 ? -15.886 2.882   55.064 1.00 21.38  ? 423 HIS C O   1 
ATOM   7027  C CB  . HIS C 1 221 ? -16.919 5.755   54.316 1.00 14.35  ? 423 HIS C CB  1 
ATOM   7028  C CG  . HIS C 1 221 ? -16.940 5.686   52.822 1.00 16.01  ? 423 HIS C CG  1 
ATOM   7029  N ND1 . HIS C 1 221 ? -18.110 5.694   52.095 1.00 17.11  ? 423 HIS C ND1 1 
ATOM   7030  C CD2 . HIS C 1 221 ? -15.939 5.566   51.920 1.00 16.34  ? 423 HIS C CD2 1 
ATOM   7031  C CE1 . HIS C 1 221 ? -17.828 5.603   50.808 1.00 17.73  ? 423 HIS C CE1 1 
ATOM   7032  N NE2 . HIS C 1 221 ? -16.517 5.524   50.675 1.00 17.58  ? 423 HIS C NE2 1 
ATOM   7033  N N   . SER C 1 222 ? -17.530 2.597   53.567 1.00 17.84  ? 424 SER C N   1 
ATOM   7034  C CA  . SER C 1 222 ? -17.006 1.354   53.045 1.00 18.16  ? 424 SER C CA  1 
ATOM   7035  C C   . SER C 1 222 ? -16.051 1.526   51.881 1.00 17.59  ? 424 SER C C   1 
ATOM   7036  O O   . SER C 1 222 ? -16.465 1.457   50.737 1.00 18.26  ? 424 SER C O   1 
ATOM   7037  C CB  . SER C 1 222 ? -18.171 0.501   52.577 1.00 19.46  ? 424 SER C CB  1 
ATOM   7038  O OG  . SER C 1 222 ? -18.878 1.158   51.547 1.00 23.05  ? 424 SER C OG  1 
ATOM   7039  N N   . SER C 1 223 ? -14.773 1.739   52.162 1.00 18.34  ? 425 SER C N   1 
ATOM   7040  C CA  . SER C 1 223 ? -13.796 1.877   51.093 1.00 17.99  ? 425 SER C CA  1 
ATOM   7041  C C   . SER C 1 223 ? -13.257 0.524   50.631 1.00 17.16  ? 425 SER C C   1 
ATOM   7042  O O   . SER C 1 223 ? -12.105 0.191   50.866 1.00 17.87  ? 425 SER C O   1 
ATOM   7043  C CB  . SER C 1 223 ? -12.652 2.791   51.521 1.00 16.08  ? 425 SER C CB  1 
ATOM   7044  O OG  . SER C 1 223 ? -12.186 2.454   52.806 1.00 18.23  ? 425 SER C OG  1 
ATOM   7045  N N   . TYR C 1 224 ? -14.110 -0.251  49.976 1.00 15.73  ? 426 TYR C N   1 
ATOM   7046  C CA  . TYR C 1 224 ? -13.742 -1.554  49.453 1.00 16.17  ? 426 TYR C CA  1 
ATOM   7047  C C   . TYR C 1 224 ? -14.694 -1.918  48.334 1.00 16.10  ? 426 TYR C C   1 
ATOM   7048  O O   . TYR C 1 224 ? -15.775 -1.357  48.230 1.00 16.47  ? 426 TYR C O   1 
ATOM   7049  C CB  . TYR C 1 224 ? -13.804 -2.621  50.542 1.00 15.19  ? 426 TYR C CB  1 
ATOM   7050  C CG  . TYR C 1 224 ? -15.177 -2.798  51.129 1.00 16.57  ? 426 TYR C CG  1 
ATOM   7051  C CD1 . TYR C 1 224 ? -16.199 -3.370  50.392 1.00 17.03  ? 426 TYR C CD1 1 
ATOM   7052  C CD2 . TYR C 1 224 ? -15.454 -2.386  52.415 1.00 17.37  ? 426 TYR C CD2 1 
ATOM   7053  C CE1 . TYR C 1 224 ? -17.457 -3.523  50.923 1.00 19.35  ? 426 TYR C CE1 1 
ATOM   7054  C CE2 . TYR C 1 224 ? -16.705 -2.539  52.955 1.00 19.37  ? 426 TYR C CE2 1 
ATOM   7055  C CZ  . TYR C 1 224 ? -17.703 -3.101  52.203 1.00 20.24  ? 426 TYR C CZ  1 
ATOM   7056  O OH  . TYR C 1 224 ? -18.950 -3.245  52.753 1.00 21.55  ? 426 TYR C OH  1 
ATOM   7057  N N   . ALA C 1 225 ? -14.294 -2.864  47.500 1.00 15.79  ? 427 ALA C N   1 
ATOM   7058  C CA  . ALA C 1 225 ? -15.130 -3.325  46.411 1.00 15.76  ? 427 ALA C CA  1 
ATOM   7059  C C   . ALA C 1 225 ? -15.384 -4.803  46.645 1.00 16.45  ? 427 ALA C C   1 
ATOM   7060  O O   . ALA C 1 225 ? -14.483 -5.522  47.036 1.00 17.11  ? 427 ALA C O   1 
ATOM   7061  C CB  . ALA C 1 225 ? -14.440 -3.101  45.083 1.00 16.40  ? 427 ALA C CB  1 
ATOM   7062  N N   . HIS C 1 226 ? -16.611 -5.262  46.451 1.00 17.11  ? 428 HIS C N   1 
ATOM   7063  C CA  . HIS C 1 226 ? -16.910 -6.673  46.663 1.00 17.15  ? 428 HIS C CA  1 
ATOM   7064  C C   . HIS C 1 226 ? -16.184 -7.581  45.685 1.00 17.61  ? 428 HIS C C   1 
ATOM   7065  O O   . HIS C 1 226 ? -16.040 -7.254  44.518 1.00 16.32  ? 428 HIS C O   1 
ATOM   7066  C CB  . HIS C 1 226 ? -18.411 -6.927  46.596 1.00 18.67  ? 428 HIS C CB  1 
ATOM   7067  C CG  . HIS C 1 226 ? -19.161 -6.393  47.771 1.00 19.81  ? 428 HIS C CG  1 
ATOM   7068  N ND1 . HIS C 1 226 ? -19.076 -6.959  49.021 1.00 19.39  ? 428 HIS C ND1 1 
ATOM   7069  C CD2 . HIS C 1 226 ? -20.001 -5.342  47.889 1.00 20.43  ? 428 HIS C CD2 1 
ATOM   7070  C CE1 . HIS C 1 226 ? -19.833 -6.280  49.860 1.00 19.81  ? 428 HIS C CE1 1 
ATOM   7071  N NE2 . HIS C 1 226 ? -20.406 -5.294  49.197 1.00 21.44  ? 428 HIS C NE2 1 
ATOM   7072  N N   . SER C 1 227 ? -15.724 -8.727  46.172 1.00 16.23  ? 429 SER C N   1 
ATOM   7073  C CA  . SER C 1 227 ? -15.025 -9.677  45.325 1.00 17.29  ? 429 SER C CA  1 
ATOM   7074  C C   . SER C 1 227 ? -15.989 -10.743 44.833 1.00 17.47  ? 429 SER C C   1 
ATOM   7075  O O   . SER C 1 227 ? -15.593 -11.679 44.152 1.00 18.01  ? 429 SER C O   1 
ATOM   7076  C CB  . SER C 1 227 ? -13.834 -10.283 46.043 1.00 17.34  ? 429 SER C CB  1 
ATOM   7077  O OG  . SER C 1 227 ? -14.105 -10.434 47.416 1.00 21.46  ? 429 SER C OG  1 
ATOM   7078  N N   . GLN C 1 228 ? -17.253 -10.608 45.220 1.00 17.92  ? 430 GLN C N   1 
ATOM   7079  C CA  . GLN C 1 228 ? -18.321 -11.473 44.750 1.00 19.22  ? 430 GLN C CA  1 
ATOM   7080  C C   . GLN C 1 228 ? -19.468 -10.630 44.219 1.00 18.82  ? 430 GLN C C   1 
ATOM   7081  O O   . GLN C 1 228 ? -19.545 -9.426  44.459 1.00 18.68  ? 430 GLN C O   1 
ATOM   7082  C CB  . GLN C 1 228 ? -18.841 -12.396 45.851 1.00 18.85  ? 430 GLN C CB  1 
ATOM   7083  C CG  . GLN C 1 228 ? -17.920 -13.526 46.208 1.00 19.60  ? 430 GLN C CG  1 
ATOM   7084  C CD  . GLN C 1 228 ? -18.482 -14.370 47.320 1.00 20.14  ? 430 GLN C CD  1 
ATOM   7085  O OE1 . GLN C 1 228 ? -19.187 -13.873 48.193 1.00 20.91  ? 430 GLN C OE1 1 
ATOM   7086  N NE2 . GLN C 1 228 ? -18.220 -15.665 47.266 1.00 18.16  ? 430 GLN C NE2 1 
ATOM   7087  N N   . SER C 1 229 ? -20.364 -11.288 43.493 1.00 19.80  ? 431 SER C N   1 
ATOM   7088  C CA  . SER C 1 229 ? -21.570 -10.674 42.967 1.00 19.62  ? 431 SER C CA  1 
ATOM   7089  C C   . SER C 1 229 ? -22.787 -11.277 43.653 1.00 19.36  ? 431 SER C C   1 
ATOM   7090  O O   . SER C 1 229 ? -22.744 -12.403 44.152 1.00 18.65  ? 431 SER C O   1 
ATOM   7091  C CB  . SER C 1 229 ? -21.671 -10.858 41.452 1.00 21.06  ? 431 SER C CB  1 
ATOM   7092  O OG  . SER C 1 229 ? -21.755 -12.225 41.109 1.00 25.54  ? 431 SER C OG  1 
ATOM   7093  N N   . LEU C 1 230 ? -23.863 -10.514 43.739 1.00 19.03  ? 432 LEU C N   1 
ATOM   7094  C CA  . LEU C 1 230 ? -25.054 -10.967 44.443 1.00 18.42  ? 432 LEU C CA  1 
ATOM   7095  C C   . LEU C 1 230 ? -25.741 -12.180 43.844 1.00 19.35  ? 432 LEU C C   1 
ATOM   7096  O O   . LEU C 1 230 ? -26.420 -12.912 44.550 1.00 19.65  ? 432 LEU C O   1 
ATOM   7097  C CB  . LEU C 1 230 ? -26.049 -9.824  44.589 1.00 18.93  ? 432 LEU C CB  1 
ATOM   7098  C CG  . LEU C 1 230 ? -27.036 -9.952  45.742 1.00 19.67  ? 432 LEU C CG  1 
ATOM   7099  C CD1 . LEU C 1 230 ? -26.303 -10.101 47.060 1.00 19.35  ? 432 LEU C CD1 1 
ATOM   7100  C CD2 . LEU C 1 230 ? -27.922 -8.728  45.776 1.00 20.05  ? 432 LEU C CD2 1 
ATOM   7101  N N   . ASP C 1 231 ? -25.587 -12.389 42.545 1.00 20.06  ? 433 ASP C N   1 
ATOM   7102  C CA  . ASP C 1 231 ? -26.212 -13.539 41.906 1.00 22.13  ? 433 ASP C CA  1 
ATOM   7103  C C   . ASP C 1 231 ? -25.314 -14.768 41.865 1.00 21.45  ? 433 ASP C C   1 
ATOM   7104  O O   . ASP C 1 231 ? -25.710 -15.800 41.348 1.00 22.52  ? 433 ASP C O   1 
ATOM   7105  C CB  . ASP C 1 231 ? -26.715 -13.188 40.509 1.00 18.91  ? 433 ASP C CB  1 
ATOM   7106  C CG  . ASP C 1 231 ? -25.644 -12.599 39.637 1.00 23.14  ? 433 ASP C CG  1 
ATOM   7107  O OD1 . ASP C 1 231 ? -24.685 -12.027 40.181 1.00 25.19  ? 433 ASP C OD1 1 
ATOM   7108  O OD2 . ASP C 1 231 ? -25.764 -12.696 38.403 1.00 26.58  ? 433 ASP C OD2 1 
ATOM   7109  N N   . ARG C 1 232 ? -24.098 -14.645 42.381 1.00 21.58  ? 434 ARG C N   1 
ATOM   7110  C CA  . ARG C 1 232 ? -23.146 -15.751 42.397 1.00 19.92  ? 434 ARG C CA  1 
ATOM   7111  C C   . ARG C 1 232 ? -22.720 -16.240 43.783 1.00 19.64  ? 434 ARG C C   1 
ATOM   7112  O O   . ARG C 1 232 ? -21.685 -16.861 43.916 1.00 19.48  ? 434 ARG C O   1 
ATOM   7113  C CB  . ARG C 1 232 ? -21.919 -15.415 41.555 1.00 19.75  ? 434 ARG C CB  1 
ATOM   7114  C CG  . ARG C 1 232 ? -22.191 -15.358 40.065 1.00 21.79  ? 434 ARG C CG  1 
ATOM   7115  C CD  . ARG C 1 232 ? -22.627 -16.708 39.539 1.00 20.40  ? 434 ARG C CD  1 
ATOM   7116  N NE  . ARG C 1 232 ? -23.038 -16.646 38.143 1.00 20.32  ? 434 ARG C NE  1 
ATOM   7117  C CZ  . ARG C 1 232 ? -24.299 -16.594 37.739 1.00 20.28  ? 434 ARG C CZ  1 
ATOM   7118  N NH1 . ARG C 1 232 ? -25.280 -16.597 38.622 1.00 19.16  ? 434 ARG C NH1 1 
ATOM   7119  N NH2 . ARG C 1 232 ? -24.580 -16.544 36.451 1.00 22.33  ? 434 ARG C NH2 1 
ATOM   7120  N N   . LEU C 1 233 ? -23.504 -15.959 44.811 1.00 19.83  ? 435 LEU C N   1 
ATOM   7121  C CA  . LEU C 1 233 ? -23.170 -16.357 46.184 1.00 19.69  ? 435 LEU C CA  1 
ATOM   7122  C C   . LEU C 1 233 ? -23.113 -17.862 46.473 1.00 20.49  ? 435 LEU C C   1 
ATOM   7123  O O   . LEU C 1 233 ? -22.454 -18.297 47.409 1.00 21.36  ? 435 LEU C O   1 
ATOM   7124  C CB  . LEU C 1 233 ? -24.102 -15.671 47.177 1.00 18.07  ? 435 LEU C CB  1 
ATOM   7125  C CG  . LEU C 1 233 ? -23.917 -14.163 47.291 1.00 18.60  ? 435 LEU C CG  1 
ATOM   7126  C CD1 . LEU C 1 233 ? -24.947 -13.577 48.236 1.00 16.44  ? 435 LEU C CD1 1 
ATOM   7127  C CD2 . LEU C 1 233 ? -22.509 -13.838 47.756 1.00 18.07  ? 435 LEU C CD2 1 
ATOM   7128  N N   . MET C 1 234 ? -23.824 -18.637 45.674 1.00 22.68  ? 436 MET C N   1 
ATOM   7129  C CA  . MET C 1 234 ? -23.938 -20.084 45.809 1.00 23.74  ? 436 MET C CA  1 
ATOM   7130  C C   . MET C 1 234 ? -22.652 -20.872 45.606 1.00 23.84  ? 436 MET C C   1 
ATOM   7131  O O   . MET C 1 234 ? -21.729 -20.411 44.954 1.00 23.81  ? 436 MET C O   1 
ATOM   7132  C CB  . MET C 1 234 ? -24.875 -20.555 44.718 1.00 27.55  ? 436 MET C CB  1 
ATOM   7133  C CG  . MET C 1 234 ? -24.194 -20.460 43.368 1.00 29.60  ? 436 MET C CG  1 
ATOM   7134  S SD  . MET C 1 234 ? -25.110 -19.460 42.198 1.00 34.23  ? 436 MET C SD  1 
ATOM   7135  C CE  . MET C 1 234 ? -26.034 -18.400 43.295 1.00 33.61  ? 436 MET C CE  1 
ATOM   7136  N N   . ASN C 1 235 ? -22.599 -22.055 46.215 1.00 23.82  ? 437 ASN C N   1 
ATOM   7137  C CA  . ASN C 1 235 ? -21.492 -22.986 46.070 1.00 22.51  ? 437 ASN C CA  1 
ATOM   7138  C C   . ASN C 1 235 ? -21.738 -23.545 44.684 1.00 21.83  ? 437 ASN C C   1 
ATOM   7139  O O   . ASN C 1 235 ? -22.818 -24.045 44.411 1.00 22.18  ? 437 ASN C O   1 
ATOM   7140  C CB  . ASN C 1 235 ? -21.655 -24.074 47.136 1.00 23.73  ? 437 ASN C CB  1 
ATOM   7141  C CG  . ASN C 1 235 ? -20.684 -25.228 46.983 1.00 24.26  ? 437 ASN C CG  1 
ATOM   7142  O OD1 . ASN C 1 235 ? -20.418 -25.694 45.888 1.00 24.56  ? 437 ASN C OD1 1 
ATOM   7143  N ND2 . ASN C 1 235 ? -20.185 -25.723 48.102 1.00 23.96  ? 437 ASN C ND2 1 
ATOM   7144  N N   . PRO C 1 236 ? -20.740 -23.485 43.796 1.00 19.56  ? 438 PRO C N   1 
ATOM   7145  C CA  . PRO C 1 236 ? -20.970 -23.972 42.434 1.00 18.89  ? 438 PRO C CA  1 
ATOM   7146  C C   . PRO C 1 236 ? -20.847 -25.476 42.264 1.00 19.06  ? 438 PRO C C   1 
ATOM   7147  O O   . PRO C 1 236 ? -21.038 -25.966 41.162 1.00 19.67  ? 438 PRO C O   1 
ATOM   7148  C CB  . PRO C 1 236 ? -19.859 -23.289 41.649 1.00 17.47  ? 438 PRO C CB  1 
ATOM   7149  C CG  . PRO C 1 236 ? -18.748 -23.184 42.629 1.00 17.98  ? 438 PRO C CG  1 
ATOM   7150  C CD  . PRO C 1 236 ? -19.365 -23.004 43.984 1.00 18.07  ? 438 PRO C CD  1 
ATOM   7151  N N   . LEU C 1 237 ? -20.546 -26.198 43.333 1.00 21.83  ? 439 LEU C N   1 
ATOM   7152  C CA  . LEU C 1 237 ? -20.376 -27.640 43.233 1.00 21.15  ? 439 LEU C CA  1 
ATOM   7153  C C   . LEU C 1 237 ? -21.611 -28.452 43.611 1.00 22.58  ? 439 LEU C C   1 
ATOM   7154  O O   . LEU C 1 237 ? -21.627 -29.662 43.366 1.00 23.00  ? 439 LEU C O   1 
ATOM   7155  C CB  . LEU C 1 237 ? -19.195 -28.076 44.105 1.00 20.71  ? 439 LEU C CB  1 
ATOM   7156  C CG  . LEU C 1 237 ? -17.862 -27.467 43.676 1.00 19.99  ? 439 LEU C CG  1 
ATOM   7157  C CD1 . LEU C 1 237 ? -16.777 -27.825 44.655 1.00 17.92  ? 439 LEU C CD1 1 
ATOM   7158  C CD2 . LEU C 1 237 ? -17.498 -27.915 42.276 1.00 17.55  ? 439 LEU C CD2 1 
ATOM   7159  N N   . ILE C 1 238 ? -22.588 -27.838 44.269 1.00 26.54  ? 440 ILE C N   1 
ATOM   7160  C CA  . ILE C 1 238 ? -23.755 -28.575 44.748 1.00 27.59  ? 440 ILE C CA  1 
ATOM   7161  C C   . ILE C 1 238 ? -25.113 -28.110 44.231 1.00 29.45  ? 440 ILE C C   1 
ATOM   7162  O O   . ILE C 1 238 ? -25.396 -26.920 44.178 1.00 30.76  ? 440 ILE C O   1 
ATOM   7163  C CB  . ILE C 1 238 ? -23.821 -28.526 46.290 1.00 29.39  ? 440 ILE C CB  1 
ATOM   7164  C CG1 . ILE C 1 238 ? -22.434 -28.704 46.899 1.00 27.33  ? 440 ILE C CG1 1 
ATOM   7165  C CG2 . ILE C 1 238 ? -24.773 -29.579 46.835 1.00 29.05  ? 440 ILE C CG2 1 
ATOM   7166  C CD1 . ILE C 1 238 ? -21.809 -30.046 46.606 1.00 24.82  ? 440 ILE C CD1 1 
ATOM   7167  N N   . ASP C 1 239 ? -25.944 -29.074 43.849 1.00 35.42  ? 441 ASP C N   1 
ATOM   7168  C CA  . ASP C 1 239 ? -27.295 -28.812 43.384 1.00 36.53  ? 441 ASP C CA  1 
ATOM   7169  C C   . ASP C 1 239 ? -28.157 -28.363 44.548 1.00 35.15  ? 441 ASP C C   1 
ATOM   7170  O O   . ASP C 1 239 ? -27.971 -28.817 45.664 1.00 36.12  ? 441 ASP C O   1 
ATOM   7171  C CB  . ASP C 1 239 ? -27.903 -30.081 42.793 1.00 38.49  ? 441 ASP C CB  1 
ATOM   7172  C CG  . ASP C 1 239 ? -27.746 -30.162 41.294 1.00 45.00  ? 441 ASP C CG  1 
ATOM   7173  O OD1 . ASP C 1 239 ? -27.351 -29.154 40.681 1.00 51.62  ? 441 ASP C OD1 1 
ATOM   7174  O OD2 . ASP C 1 239 ? -28.027 -31.235 40.723 1.00 46.55  ? 441 ASP C OD2 1 
ATOM   7175  N N   . GLN C 1 240 ? -29.084 -27.453 44.290 1.00 39.85  ? 442 GLN C N   1 
ATOM   7176  C CA  . GLN C 1 240 ? -30.007 -26.978 45.312 1.00 38.61  ? 442 GLN C CA  1 
ATOM   7177  C C   . GLN C 1 240 ? -31.119 -27.997 45.526 1.00 38.49  ? 442 GLN C C   1 
ATOM   7178  O O   . GLN C 1 240 ? -31.381 -28.811 44.650 1.00 38.46  ? 442 GLN C O   1 
ATOM   7179  C CB  . GLN C 1 240 ? -30.622 -25.645 44.888 1.00 36.34  ? 442 GLN C CB  1 
ATOM   7180  C CG  . GLN C 1 240 ? -29.795 -24.422 45.227 1.00 34.58  ? 442 GLN C CG  1 
ATOM   7181  C CD  . GLN C 1 240 ? -30.605 -23.152 45.125 1.00 34.71  ? 442 GLN C CD  1 
ATOM   7182  O OE1 . GLN C 1 240 ? -31.513 -23.051 44.308 1.00 33.62  ? 442 GLN C OE1 1 
ATOM   7183  N NE2 . GLN C 1 240 ? -30.282 -22.175 45.959 1.00 34.83  ? 442 GLN C NE2 1 
ATOM   7184  N N   . TYR C 1 241 ? -31.773 -27.976 46.682 1.00 39.55  ? 443 TYR C N   1 
ATOM   7185  C CA  . TYR C 1 241 ? -32.889 -28.899 46.891 1.00 38.11  ? 443 TYR C CA  1 
ATOM   7186  C C   . TYR C 1 241 ? -34.221 -28.316 46.415 1.00 37.74  ? 443 TYR C C   1 
ATOM   7187  O O   . TYR C 1 241 ? -35.252 -28.975 46.479 1.00 39.02  ? 443 TYR C O   1 
ATOM   7188  C CB  . TYR C 1 241 ? -32.986 -29.427 48.324 1.00 36.48  ? 443 TYR C CB  1 
ATOM   7189  C CG  . TYR C 1 241 ? -32.848 -28.403 49.410 1.00 36.04  ? 443 TYR C CG  1 
ATOM   7190  C CD1 . TYR C 1 241 ? -33.914 -27.608 49.783 1.00 35.64  ? 443 TYR C CD1 1 
ATOM   7191  C CD2 . TYR C 1 241 ? -31.656 -28.255 50.089 1.00 36.91  ? 443 TYR C CD2 1 
ATOM   7192  C CE1 . TYR C 1 241 ? -33.789 -26.674 50.791 1.00 35.80  ? 443 TYR C CE1 1 
ATOM   7193  C CE2 . TYR C 1 241 ? -31.520 -27.325 51.094 1.00 36.97  ? 443 TYR C CE2 1 
ATOM   7194  C CZ  . TYR C 1 241 ? -32.589 -26.539 51.440 1.00 36.59  ? 443 TYR C CZ  1 
ATOM   7195  O OH  . TYR C 1 241 ? -32.452 -25.620 52.444 1.00 36.42  ? 443 TYR C OH  1 
ATOM   7196  N N   . LEU C 1 242 ? -34.194 -27.063 45.979 1.00 38.91  ? 444 LEU C N   1 
ATOM   7197  C CA  . LEU C 1 242 ? -35.370 -26.393 45.446 1.00 39.06  ? 444 LEU C CA  1 
ATOM   7198  C C   . LEU C 1 242 ? -35.596 -26.800 43.994 1.00 39.67  ? 444 LEU C C   1 
ATOM   7199  O O   . LEU C 1 242 ? -34.679 -27.264 43.333 1.00 39.96  ? 444 LEU C O   1 
ATOM   7200  C CB  . LEU C 1 242 ? -35.222 -24.881 45.564 1.00 38.42  ? 444 LEU C CB  1 
ATOM   7201  C CG  . LEU C 1 242 ? -35.009 -24.377 46.989 1.00 37.84  ? 444 LEU C CG  1 
ATOM   7202  C CD1 . LEU C 1 242 ? -34.838 -22.871 46.996 1.00 37.11  ? 444 LEU C CD1 1 
ATOM   7203  C CD2 . LEU C 1 242 ? -36.163 -24.793 47.883 1.00 37.05  ? 444 LEU C CD2 1 
ATOM   7204  N N   . TYR C 1 243 ? -36.815 -26.617 43.500 1.00 41.80  ? 445 TYR C N   1 
ATOM   7205  C CA  . TYR C 1 243 ? -37.162 -26.972 42.125 1.00 41.82  ? 445 TYR C CA  1 
ATOM   7206  C C   . TYR C 1 243 ? -37.713 -25.783 41.355 1.00 41.85  ? 445 TYR C C   1 
ATOM   7207  O O   . TYR C 1 243 ? -38.285 -24.874 41.936 1.00 41.81  ? 445 TYR C O   1 
ATOM   7208  C CB  . TYR C 1 243 ? -38.180 -28.114 42.099 1.00 44.17  ? 445 TYR C CB  1 
ATOM   7209  C CG  . TYR C 1 243 ? -37.549 -29.480 42.136 1.00 46.36  ? 445 TYR C CG  1 
ATOM   7210  C CD1 . TYR C 1 243 ? -37.433 -30.243 40.987 1.00 47.55  ? 445 TYR C CD1 1 
ATOM   7211  C CD2 . TYR C 1 243 ? -37.049 -29.997 43.319 1.00 46.64  ? 445 TYR C CD2 1 
ATOM   7212  C CE1 . TYR C 1 243 ? -36.845 -31.488 41.018 1.00 48.31  ? 445 TYR C CE1 1 
ATOM   7213  C CE2 . TYR C 1 243 ? -36.457 -31.238 43.360 1.00 47.35  ? 445 TYR C CE2 1 
ATOM   7214  C CZ  . TYR C 1 243 ? -36.358 -31.978 42.208 1.00 48.05  ? 445 TYR C CZ  1 
ATOM   7215  O OH  . TYR C 1 243 ? -35.770 -33.217 42.255 1.00 49.19  ? 445 TYR C OH  1 
ATOM   7216  N N   . TYR C 1 244 ? -37.500 -25.775 40.047 1.00 39.48  ? 446 TYR C N   1 
ATOM   7217  C CA  . TYR C 1 244 ? -37.991 -24.698 39.207 1.00 39.83  ? 446 TYR C CA  1 
ATOM   7218  C C   . TYR C 1 244 ? -38.653 -25.298 37.986 1.00 40.19  ? 446 TYR C C   1 
ATOM   7219  O O   . TYR C 1 244 ? -38.241 -26.347 37.516 1.00 40.02  ? 446 TYR C O   1 
ATOM   7220  C CB  . TYR C 1 244 ? -36.845 -23.790 38.774 1.00 36.16  ? 446 TYR C CB  1 
ATOM   7221  C CG  . TYR C 1 244 ? -36.020 -24.355 37.643 1.00 36.54  ? 446 TYR C CG  1 
ATOM   7222  C CD1 . TYR C 1 244 ? -36.283 -24.010 36.331 1.00 35.54  ? 446 TYR C CD1 1 
ATOM   7223  C CD2 . TYR C 1 244 ? -34.980 -25.232 37.891 1.00 37.52  ? 446 TYR C CD2 1 
ATOM   7224  C CE1 . TYR C 1 244 ? -35.537 -24.527 35.295 1.00 37.33  ? 446 TYR C CE1 1 
ATOM   7225  C CE2 . TYR C 1 244 ? -34.228 -25.755 36.862 1.00 38.36  ? 446 TYR C CE2 1 
ATOM   7226  C CZ  . TYR C 1 244 ? -34.513 -25.398 35.566 1.00 38.67  ? 446 TYR C CZ  1 
ATOM   7227  O OH  . TYR C 1 244 ? -33.770 -25.911 34.535 1.00 39.27  ? 446 TYR C OH  1 
ATOM   7228  N N   . LEU C 1 245 ? -39.674 -24.633 37.468 1.00 39.82  ? 447 LEU C N   1 
ATOM   7229  C CA  . LEU C 1 245 ? -40.377 -25.116 36.291 1.00 41.49  ? 447 LEU C CA  1 
ATOM   7230  C C   . LEU C 1 245 ? -39.507 -24.943 35.054 1.00 43.37  ? 447 LEU C C   1 
ATOM   7231  O O   . LEU C 1 245 ? -39.154 -23.827 34.699 1.00 44.08  ? 447 LEU C O   1 
ATOM   7232  C CB  . LEU C 1 245 ? -41.689 -24.358 36.137 1.00 44.05  ? 447 LEU C CB  1 
ATOM   7233  C CG  . LEU C 1 245 ? -42.553 -24.699 34.934 1.00 44.35  ? 447 LEU C CG  1 
ATOM   7234  C CD1 . LEU C 1 245 ? -42.691 -26.203 34.808 1.00 43.30  ? 447 LEU C CD1 1 
ATOM   7235  C CD2 . LEU C 1 245 ? -43.909 -24.034 35.079 1.00 44.98  ? 447 LEU C CD2 1 
ATOM   7236  N N   . SER C 1 246 ? -39.169 -26.051 34.402 1.00 40.08  ? 448 SER C N   1 
ATOM   7237  C CA  . SER C 1 246 ? -38.314 -26.051 33.223 1.00 41.73  ? 448 SER C CA  1 
ATOM   7238  C C   . SER C 1 246 ? -39.086 -26.033 31.908 1.00 43.36  ? 448 SER C C   1 
ATOM   7239  O O   . SER C 1 246 ? -38.716 -25.294 30.991 1.00 44.65  ? 448 SER C O   1 
ATOM   7240  C CB  . SER C 1 246 ? -37.382 -27.262 33.261 1.00 48.28  ? 448 SER C CB  1 
ATOM   7241  O OG  . SER C 1 246 ? -38.119 -28.467 33.230 1.00 49.87  ? 448 SER C OG  1 
ATOM   7242  N N   . LYS C 1 247 ? -40.144 -26.834 31.786 1.00 44.87  ? 449 LYS C N   1 
ATOM   7243  C CA  . LYS C 1 247 ? -40.881 -26.959 30.532 1.00 46.50  ? 449 LYS C CA  1 
ATOM   7244  C C   . LYS C 1 247 ? -42.362 -26.731 30.771 1.00 47.55  ? 449 LYS C C   1 
ATOM   7245  O O   . LYS C 1 247 ? -42.965 -27.400 31.615 1.00 48.45  ? 449 LYS C O   1 
ATOM   7246  C CB  . LYS C 1 247 ? -40.687 -28.340 29.893 1.00 47.23  ? 449 LYS C CB  1 
ATOM   7247  C CG  . LYS C 1 247 ? -39.301 -28.620 29.367 1.00 49.60  ? 449 LYS C CG  1 
ATOM   7248  C CD  . LYS C 1 247 ? -39.232 -30.020 28.784 1.00 52.40  ? 449 LYS C CD  1 
ATOM   7249  C CE  . LYS C 1 247 ? -37.861 -30.311 28.204 1.00 55.18  ? 449 LYS C CE  1 
ATOM   7250  N NZ  . LYS C 1 247 ? -37.764 -31.700 27.678 1.00 57.94  ? 449 LYS C NZ  1 
ATOM   7251  N N   . THR C 1 248 ? -42.946 -25.789 30.031 1.00 51.28  ? 450 THR C N   1 
ATOM   7252  C CA  . THR C 1 248 ? -44.388 -25.596 30.049 1.00 52.37  ? 450 THR C CA  1 
ATOM   7253  C C   . THR C 1 248 ? -45.114 -26.358 28.945 1.00 53.62  ? 450 THR C C   1 
ATOM   7254  O O   . THR C 1 248 ? -46.343 -26.461 28.997 1.00 53.60  ? 450 THR C O   1 
ATOM   7255  C CB  . THR C 1 248 ? -44.729 -24.107 29.942 1.00 48.98  ? 450 THR C CB  1 
ATOM   7256  O OG1 . THR C 1 248 ? -44.219 -23.584 28.712 1.00 49.64  ? 450 THR C OG1 1 
ATOM   7257  C CG2 . THR C 1 248 ? -44.119 -23.344 31.100 1.00 48.16  ? 450 THR C CG2 1 
ATOM   7258  N N   . ILE C 1 249 ? -44.391 -26.832 27.931 1.00 54.84  ? 451 ILE C N   1 
ATOM   7259  C CA  . ILE C 1 249 ? -44.994 -27.611 26.844 1.00 56.63  ? 451 ILE C CA  1 
ATOM   7260  C C   . ILE C 1 249 ? -44.087 -28.768 26.449 1.00 58.29  ? 451 ILE C C   1 
ATOM   7261  O O   . ILE C 1 249 ? -42.872 -28.614 26.368 1.00 58.82  ? 451 ILE C O   1 
ATOM   7262  C CB  . ILE C 1 249 ? -45.294 -26.788 25.573 1.00 54.20  ? 451 ILE C CB  1 
ATOM   7263  C CG1 . ILE C 1 249 ? -44.010 -26.216 24.981 1.00 54.20  ? 451 ILE C CG1 1 
ATOM   7264  C CG2 . ILE C 1 249 ? -46.321 -25.700 25.842 1.00 54.20  ? 451 ILE C CG2 1 
ATOM   7265  C CD1 . ILE C 1 249 ? -44.220 -25.483 23.678 1.00 54.20  ? 451 ILE C CD1 1 
ATOM   7266  N N   . ASN C 1 250 ? -44.685 -29.931 26.217 1.00 58.67  ? 452 ASN C N   1 
ATOM   7267  C CA  . ASN C 1 250 ? -43.929 -31.117 25.842 1.00 61.04  ? 452 ASN C CA  1 
ATOM   7268  C C   . ASN C 1 250 ? -43.211 -30.989 24.506 1.00 62.52  ? 452 ASN C C   1 
ATOM   7269  O O   . ASN C 1 250 ? -42.053 -31.371 24.382 1.00 62.67  ? 452 ASN C O   1 
ATOM   7270  C CB  . ASN C 1 250 ? -44.862 -32.326 25.796 1.00 57.22  ? 452 ASN C CB  1 
ATOM   7271  C CG  . ASN C 1 250 ? -45.316 -32.760 27.170 1.00 59.42  ? 452 ASN C CG  1 
ATOM   7272  O OD1 . ASN C 1 250 ? -46.509 -32.839 27.446 1.00 60.90  ? 452 ASN C OD1 1 
ATOM   7273  N ND2 . ASN C 1 250 ? -44.360 -33.040 28.045 1.00 60.74  ? 452 ASN C ND2 1 
ATOM   7274  N N   . GLY C 1 251 ? -43.906 -30.451 23.512 1.00 61.85  ? 453 GLY C N   1 
ATOM   7275  C CA  . GLY C 1 251 ? -43.358 -30.285 22.178 1.00 64.20  ? 453 GLY C CA  1 
ATOM   7276  C C   . GLY C 1 251 ? -44.181 -29.302 21.376 1.00 66.21  ? 453 GLY C C   1 
ATOM   7277  O O   . GLY C 1 251 ? -45.240 -28.885 21.821 1.00 67.20  ? 453 GLY C O   1 
ATOM   7278  N N   . SER C 1 252 ? -43.693 -28.887 20.215 1.00 68.22  ? 454 SER C N   1 
ATOM   7279  C CA  . SER C 1 252 ? -44.473 -27.977 19.392 1.00 68.72  ? 454 SER C CA  1 
ATOM   7280  C C   . SER C 1 252 ? -45.738 -28.693 18.924 1.00 67.97  ? 454 SER C C   1 
ATOM   7281  O O   . SER C 1 252 ? -45.681 -29.839 18.480 1.00 67.45  ? 454 SER C O   1 
ATOM   7282  C CB  . SER C 1 252 ? -43.663 -27.542 18.179 1.00 67.96  ? 454 SER C CB  1 
ATOM   7283  O OG  . SER C 1 252 ? -43.453 -28.636 17.307 1.00 69.96  ? 454 SER C OG  1 
ATOM   7284  N N   . GLY C 1 253 ? -46.878 -28.018 19.015 1.00 67.24  ? 455 GLY C N   1 
ATOM   7285  C CA  . GLY C 1 253 ? -48.136 -28.600 18.586 1.00 66.65  ? 455 GLY C CA  1 
ATOM   7286  C C   . GLY C 1 253 ? -49.303 -28.154 19.445 1.00 66.49  ? 455 GLY C C   1 
ATOM   7287  O O   . GLY C 1 253 ? -49.129 -27.380 20.385 1.00 66.26  ? 455 GLY C O   1 
ATOM   7288  N N   . GLN C 1 254 ? -50.494 -28.644 19.115 1.00 67.31  ? 456 GLN C N   1 
ATOM   7289  C CA  . GLN C 1 254 ? -51.708 -28.320 19.857 1.00 67.74  ? 456 GLN C CA  1 
ATOM   7290  C C   . GLN C 1 254 ? -51.852 -29.150 21.130 1.00 66.03  ? 456 GLN C C   1 
ATOM   7291  O O   . GLN C 1 254 ? -51.437 -30.304 21.169 1.00 66.18  ? 456 GLN C O   1 
ATOM   7292  C CB  . GLN C 1 254 ? -52.935 -28.517 18.972 1.00 67.88  ? 456 GLN C CB  1 
ATOM   7293  C CG  . GLN C 1 254 ? -52.749 -28.038 17.543 1.00 73.64  ? 456 GLN C CG  1 
ATOM   7294  C CD  . GLN C 1 254 ? -52.365 -26.576 17.464 1.00 77.00  ? 456 GLN C CD  1 
ATOM   7295  O OE1 . GLN C 1 254 ? -51.690 -26.152 16.529 1.00 77.91  ? 456 GLN C OE1 1 
ATOM   7296  N NE2 . GLN C 1 254 ? -52.794 -25.797 18.448 1.00 78.15  ? 456 GLN C NE2 1 
ATOM   7297  N N   . ASN C 1 255 ? -52.411 -28.539 22.172 1.00 65.93  ? 457 ASN C N   1 
ATOM   7298  C CA  . ASN C 1 255 ? -52.662 -29.204 23.455 1.00 64.19  ? 457 ASN C CA  1 
ATOM   7299  C C   . ASN C 1 255 ? -51.428 -29.862 24.062 1.00 62.25  ? 457 ASN C C   1 
ATOM   7300  O O   . ASN C 1 255 ? -51.508 -30.962 24.604 1.00 61.34  ? 457 ASN C O   1 
ATOM   7301  C CB  . ASN C 1 255 ? -53.804 -30.221 23.341 1.00 66.46  ? 457 ASN C CB  1 
ATOM   7302  C CG  . ASN C 1 255 ? -55.084 -29.605 22.819 1.00 67.74  ? 457 ASN C CG  1 
ATOM   7303  O OD1 . ASN C 1 255 ? -55.066 -28.552 22.185 1.00 68.54  ? 457 ASN C OD1 1 
ATOM   7304  N ND2 . ASN C 1 255 ? -56.206 -30.265 23.082 1.00 68.48  ? 457 ASN C ND2 1 
ATOM   7305  N N   . GLN C 1 256 ? -50.293 -29.183 23.980 1.00 61.12  ? 458 GLN C N   1 
ATOM   7306  C CA  . GLN C 1 256 ? -49.044 -29.727 24.497 1.00 59.36  ? 458 GLN C CA  1 
ATOM   7307  C C   . GLN C 1 256 ? -48.623 -29.222 25.870 1.00 57.53  ? 458 GLN C C   1 
ATOM   7308  O O   . GLN C 1 256 ? -47.546 -29.554 26.339 1.00 57.45  ? 458 GLN C O   1 
ATOM   7309  C CB  . GLN C 1 256 ? -47.928 -29.479 23.490 1.00 60.37  ? 458 GLN C CB  1 
ATOM   7310  C CG  . GLN C 1 256 ? -48.211 -30.076 22.127 1.00 62.97  ? 458 GLN C CG  1 
ATOM   7311  C CD  . GLN C 1 256 ? -47.852 -31.541 22.061 1.00 65.36  ? 458 GLN C CD  1 
ATOM   7312  O OE1 . GLN C 1 256 ? -46.677 -31.901 22.059 1.00 66.55  ? 458 GLN C OE1 1 
ATOM   7313  N NE2 . GLN C 1 256 ? -48.863 -32.396 22.003 1.00 66.69  ? 458 GLN C NE2 1 
ATOM   7314  N N   . GLN C 1 257 ? -49.466 -28.440 26.528 1.00 59.63  ? 459 GLN C N   1 
ATOM   7315  C CA  . GLN C 1 257 ? -49.087 -27.896 27.824 1.00 57.72  ? 459 GLN C CA  1 
ATOM   7316  C C   . GLN C 1 257 ? -48.825 -28.987 28.851 1.00 56.92  ? 459 GLN C C   1 
ATOM   7317  O O   . GLN C 1 257 ? -49.552 -29.968 28.923 1.00 57.19  ? 459 GLN C O   1 
ATOM   7318  C CB  . GLN C 1 257 ? -50.159 -26.940 28.356 1.00 57.73  ? 459 GLN C CB  1 
ATOM   7319  C CG  . GLN C 1 257 ? -50.725 -25.976 27.330 1.00 58.58  ? 459 GLN C CG  1 
ATOM   7320  C CD  . GLN C 1 257 ? -51.816 -26.608 26.504 1.00 57.95  ? 459 GLN C CD  1 
ATOM   7321  O OE1 . GLN C 1 257 ? -51.965 -27.823 26.493 1.00 57.98  ? 459 GLN C OE1 1 
ATOM   7322  N NE2 . GLN C 1 257 ? -52.589 -25.786 25.809 1.00 56.90  ? 459 GLN C NE2 1 
ATOM   7323  N N   . THR C 1 258 ? -47.772 -28.799 29.642 1.00 56.02  ? 460 THR C N   1 
ATOM   7324  C CA  . THR C 1 258 ? -47.391 -29.747 30.679 1.00 55.92  ? 460 THR C CA  1 
ATOM   7325  C C   . THR C 1 258 ? -46.601 -29.063 31.787 1.00 54.06  ? 460 THR C C   1 
ATOM   7326  O O   . THR C 1 258 ? -46.058 -27.988 31.597 1.00 54.41  ? 460 THR C O   1 
ATOM   7327  C CB  . THR C 1 258 ? -46.514 -30.866 30.106 1.00 54.86  ? 460 THR C CB  1 
ATOM   7328  O OG1 . THR C 1 258 ? -46.168 -31.782 31.150 1.00 54.49  ? 460 THR C OG1 1 
ATOM   7329  C CG2 . THR C 1 258 ? -45.248 -30.288 29.523 1.00 56.99  ? 460 THR C CG2 1 
ATOM   7330  N N   . LEU C 1 259 ? -46.551 -29.663 32.966 1.00 54.50  ? 461 LEU C N   1 
ATOM   7331  C CA  . LEU C 1 259 ? -45.769 -29.065 34.032 1.00 51.70  ? 461 LEU C CA  1 
ATOM   7332  C C   . LEU C 1 259 ? -44.610 -29.996 34.335 1.00 51.84  ? 461 LEU C C   1 
ATOM   7333  O O   . LEU C 1 259 ? -44.815 -31.106 34.805 1.00 53.13  ? 461 LEU C O   1 
ATOM   7334  C CB  . LEU C 1 259 ? -46.633 -28.875 35.277 1.00 54.43  ? 461 LEU C CB  1 
ATOM   7335  C CG  . LEU C 1 259 ? -47.456 -27.595 35.447 1.00 52.29  ? 461 LEU C CG  1 
ATOM   7336  C CD1 . LEU C 1 259 ? -47.817 -26.930 34.132 1.00 50.57  ? 461 LEU C CD1 1 
ATOM   7337  C CD2 . LEU C 1 259 ? -48.694 -27.844 36.291 1.00 50.49  ? 461 LEU C CD2 1 
ATOM   7338  N N   . LYS C 1 260 ? -43.391 -29.532 34.086 1.00 48.69  ? 462 LYS C N   1 
ATOM   7339  C CA  . LYS C 1 260 ? -42.190 -30.318 34.339 1.00 48.12  ? 462 LYS C CA  1 
ATOM   7340  C C   . LYS C 1 260 ? -41.224 -29.507 35.179 1.00 47.17  ? 462 LYS C C   1 
ATOM   7341  O O   . LYS C 1 260 ? -40.966 -28.352 34.880 1.00 46.69  ? 462 LYS C O   1 
ATOM   7342  C CB  . LYS C 1 260 ? -41.526 -30.713 33.028 1.00 47.66  ? 462 LYS C CB  1 
ATOM   7343  C CG  . LYS C 1 260 ? -42.435 -31.467 32.081 1.00 49.43  ? 462 LYS C CG  1 
ATOM   7344  C CD  . LYS C 1 260 ? -42.616 -32.906 32.519 1.00 50.23  ? 462 LYS C CD  1 
ATOM   7345  C CE  . LYS C 1 260 ? -43.375 -33.695 31.468 1.00 52.39  ? 462 LYS C CE  1 
ATOM   7346  N NZ  . LYS C 1 260 ? -43.266 -35.159 31.698 1.00 54.06  ? 462 LYS C NZ  1 
ATOM   7347  N N   . PHE C 1 261 ? -40.678 -30.116 36.221 1.00 47.90  ? 463 PHE C N   1 
ATOM   7348  C CA  . PHE C 1 261 ? -39.752 -29.420 37.096 1.00 46.53  ? 463 PHE C CA  1 
ATOM   7349  C C   . PHE C 1 261 ? -38.354 -30.021 37.079 1.00 46.29  ? 463 PHE C C   1 
ATOM   7350  O O   . PHE C 1 261 ? -38.184 -31.216 36.877 1.00 46.63  ? 463 PHE C O   1 
ATOM   7351  C CB  . PHE C 1 261 ? -40.308 -29.397 38.513 1.00 47.97  ? 463 PHE C CB  1 
ATOM   7352  C CG  . PHE C 1 261 ? -41.685 -28.820 38.602 1.00 46.45  ? 463 PHE C CG  1 
ATOM   7353  C CD1 . PHE C 1 261 ? -41.881 -27.534 39.056 1.00 45.53  ? 463 PHE C CD1 1 
ATOM   7354  C CD2 . PHE C 1 261 ? -42.782 -29.560 38.208 1.00 46.22  ? 463 PHE C CD2 1 
ATOM   7355  C CE1 . PHE C 1 261 ? -43.148 -26.997 39.130 1.00 44.43  ? 463 PHE C CE1 1 
ATOM   7356  C CE2 . PHE C 1 261 ? -44.054 -29.032 38.280 1.00 45.32  ? 463 PHE C CE2 1 
ATOM   7357  C CZ  . PHE C 1 261 ? -44.237 -27.747 38.741 1.00 44.46  ? 463 PHE C CZ  1 
ATOM   7358  N N   . SER C 1 262 ? -37.357 -29.172 37.287 1.00 41.58  ? 464 SER C N   1 
ATOM   7359  C CA  . SER C 1 262 ? -35.964 -29.585 37.302 1.00 42.08  ? 464 SER C CA  1 
ATOM   7360  C C   . SER C 1 262 ? -35.298 -29.038 38.554 1.00 42.22  ? 464 SER C C   1 
ATOM   7361  O O   . SER C 1 262 ? -35.715 -28.020 39.109 1.00 42.13  ? 464 SER C O   1 
ATOM   7362  C CB  . SER C 1 262 ? -35.216 -29.103 36.055 1.00 45.78  ? 464 SER C CB  1 
ATOM   7363  O OG  . SER C 1 262 ? -35.739 -29.698 34.883 1.00 46.03  ? 464 SER C OG  1 
ATOM   7364  N N   . VAL C 1 263 ? -34.260 -29.735 39.001 1.00 40.51  ? 465 VAL C N   1 
ATOM   7365  C CA  . VAL C 1 263 ? -33.481 -29.293 40.150 1.00 41.75  ? 465 VAL C CA  1 
ATOM   7366  C C   . VAL C 1 263 ? -32.696 -28.049 39.773 1.00 42.43  ? 465 VAL C C   1 
ATOM   7367  O O   . VAL C 1 263 ? -32.108 -27.970 38.688 1.00 42.72  ? 465 VAL C O   1 
ATOM   7368  C CB  . VAL C 1 263 ? -32.544 -30.412 40.640 1.00 42.78  ? 465 VAL C CB  1 
ATOM   7369  C CG1 . VAL C 1 263 ? -31.599 -29.883 41.695 1.00 43.03  ? 465 VAL C CG1 1 
ATOM   7370  C CG2 . VAL C 1 263 ? -33.341 -31.554 41.216 1.00 43.39  ? 465 VAL C CG2 1 
ATOM   7371  N N   . ALA C 1 264 ? -32.688 -27.068 40.669 1.00 37.94  ? 466 ALA C N   1 
ATOM   7372  C CA  . ALA C 1 264 ? -31.834 -25.904 40.502 1.00 39.16  ? 466 ALA C CA  1 
ATOM   7373  C C   . ALA C 1 264 ? -30.398 -26.298 40.815 1.00 40.63  ? 466 ALA C C   1 
ATOM   7374  O O   . ALA C 1 264 ? -30.099 -26.761 41.919 1.00 41.09  ? 466 ALA C O   1 
ATOM   7375  C CB  . ALA C 1 264 ? -32.295 -24.769 41.411 1.00 34.62  ? 466 ALA C CB  1 
ATOM   7376  N N   . GLY C 1 265 ? -29.512 -26.108 39.848 1.00 35.67  ? 467 GLY C N   1 
ATOM   7377  C CA  . GLY C 1 265 ? -28.168 -26.614 39.951 1.00 36.51  ? 467 GLY C CA  1 
ATOM   7378  C C   . GLY C 1 265 ? -27.170 -25.732 39.238 1.00 36.77  ? 467 GLY C C   1 
ATOM   7379  O O   . GLY C 1 265 ? -27.529 -24.762 38.570 1.00 36.52  ? 467 GLY C O   1 
ATOM   7380  N N   . PRO C 1 266 ? -25.889 -26.054 39.375 1.00 32.68  ? 468 PRO C N   1 
ATOM   7381  C CA  . PRO C 1 266 ? -24.845 -25.194 38.801 1.00 33.07  ? 468 PRO C CA  1 
ATOM   7382  C C   . PRO C 1 266 ? -24.915 -25.065 37.293 1.00 33.67  ? 468 PRO C C   1 
ATOM   7383  O O   . PRO C 1 266 ? -24.400 -24.085 36.742 1.00 33.54  ? 468 PRO C O   1 
ATOM   7384  C CB  . PRO C 1 266 ? -23.556 -25.894 39.242 1.00 31.60  ? 468 PRO C CB  1 
ATOM   7385  C CG  . PRO C 1 266 ? -23.958 -26.687 40.446 1.00 31.52  ? 468 PRO C CG  1 
ATOM   7386  C CD  . PRO C 1 266 ? -25.320 -27.171 40.140 1.00 31.89  ? 468 PRO C CD  1 
ATOM   7387  N N   . SER C 1 267 ? -25.525 -26.030 36.604 1.00 34.32  ? 469 SER C N   1 
ATOM   7388  C CA  . SER C 1 267 ? -25.626 -25.941 35.152 1.00 35.10  ? 469 SER C CA  1 
ATOM   7389  C C   . SER C 1 267 ? -26.516 -24.784 34.724 1.00 35.06  ? 469 SER C C   1 
ATOM   7390  O O   . SER C 1 267 ? -26.222 -24.117 33.727 1.00 35.26  ? 469 SER C O   1 
ATOM   7391  C CB  . SER C 1 267 ? -26.146 -27.257 34.578 1.00 37.22  ? 469 SER C CB  1 
ATOM   7392  O OG  . SER C 1 267 ? -27.452 -27.538 35.047 1.00 41.76  ? 469 SER C OG  1 
ATOM   7393  N N   . ASN C 1 268 ? -27.604 -24.538 35.445 1.00 34.35  ? 470 ASN C N   1 
ATOM   7394  C CA  . ASN C 1 268 ? -28.423 -23.347 35.246 1.00 33.07  ? 470 ASN C CA  1 
ATOM   7395  C C   . ASN C 1 268 ? -28.444 -22.589 36.568 1.00 31.61  ? 470 ASN C C   1 
ATOM   7396  O O   . ASN C 1 268 ? -29.151 -22.976 37.502 1.00 30.48  ? 470 ASN C O   1 
ATOM   7397  C CB  . ASN C 1 268 ? -29.825 -23.742 34.789 1.00 33.66  ? 470 ASN C CB  1 
ATOM   7398  C CG  . ASN C 1 268 ? -30.649 -22.560 34.336 1.00 36.30  ? 470 ASN C CG  1 
ATOM   7399  O OD1 . ASN C 1 268 ? -30.116 -21.550 33.882 1.00 37.14  ? 470 ASN C OD1 1 
ATOM   7400  N ND2 . ASN C 1 268 ? -31.963 -22.691 34.433 1.00 37.13  ? 470 ASN C ND2 1 
ATOM   7401  N N   . MET C 1 269 ? -27.706 -21.482 36.632 1.00 32.23  ? 471 MET C N   1 
ATOM   7402  C CA  . MET C 1 269 ? -27.599 -20.706 37.858 1.00 32.01  ? 471 MET C CA  1 
ATOM   7403  C C   . MET C 1 269 ? -28.577 -19.546 37.930 1.00 30.81  ? 471 MET C C   1 
ATOM   7404  O O   . MET C 1 269 ? -28.693 -18.920 38.988 1.00 31.48  ? 471 MET C O   1 
ATOM   7405  C CB  . MET C 1 269 ? -26.175 -20.173 38.030 1.00 25.93  ? 471 MET C CB  1 
ATOM   7406  C CG  . MET C 1 269 ? -25.147 -21.241 38.324 1.00 28.68  ? 471 MET C CG  1 
ATOM   7407  S SD  . MET C 1 269 ? -23.491 -20.567 38.542 1.00 30.58  ? 471 MET C SD  1 
ATOM   7408  C CE  . MET C 1 269 ? -22.574 -22.055 38.926 1.00 30.73  ? 471 MET C CE  1 
ATOM   7409  N N   . ALA C 1 270 ? -29.282 -19.243 36.841 1.00 30.26  ? 472 ALA C N   1 
ATOM   7410  C CA  . ALA C 1 270 ? -30.152 -18.076 36.843 1.00 28.55  ? 472 ALA C CA  1 
ATOM   7411  C C   . ALA C 1 270 ? -31.450 -18.339 37.590 1.00 27.61  ? 472 ALA C C   1 
ATOM   7412  O O   . ALA C 1 270 ? -32.086 -17.397 38.073 1.00 27.45  ? 472 ALA C O   1 
ATOM   7413  C CB  . ALA C 1 270 ? -30.445 -17.641 35.409 1.00 26.32  ? 472 ALA C CB  1 
ATOM   7414  N N   . VAL C 1 271 ? -31.866 -19.602 37.691 1.00 28.71  ? 473 VAL C N   1 
ATOM   7415  C CA  . VAL C 1 271 ? -33.161 -19.936 38.262 1.00 27.56  ? 473 VAL C CA  1 
ATOM   7416  C C   . VAL C 1 271 ? -33.080 -20.342 39.723 1.00 26.05  ? 473 VAL C C   1 
ATOM   7417  O O   . VAL C 1 271 ? -34.122 -20.609 40.335 1.00 25.55  ? 473 VAL C O   1 
ATOM   7418  C CB  . VAL C 1 271 ? -33.840 -21.047 37.443 1.00 28.11  ? 473 VAL C CB  1 
ATOM   7419  C CG1 . VAL C 1 271 ? -34.086 -20.568 36.026 1.00 32.46  ? 473 VAL C CG1 1 
ATOM   7420  C CG2 . VAL C 1 271 ? -32.988 -22.293 37.456 1.00 28.71  ? 473 VAL C CG2 1 
ATOM   7421  N N   . GLN C 1 272 ? -31.886 -20.398 40.305 1.00 30.62  ? 474 GLN C N   1 
ATOM   7422  C CA  . GLN C 1 272 ? -31.773 -20.864 41.678 1.00 29.19  ? 474 GLN C CA  1 
ATOM   7423  C C   . GLN C 1 272 ? -32.375 -19.854 42.643 1.00 28.73  ? 474 GLN C C   1 
ATOM   7424  O O   . GLN C 1 272 ? -32.346 -18.644 42.410 1.00 29.23  ? 474 GLN C O   1 
ATOM   7425  C CB  . GLN C 1 272 ? -30.319 -21.117 42.060 1.00 27.92  ? 474 GLN C CB  1 
ATOM   7426  C CG  . GLN C 1 272 ? -29.636 -22.213 41.282 1.00 30.96  ? 474 GLN C CG  1 
ATOM   7427  C CD  . GLN C 1 272 ? -28.265 -22.508 41.828 1.00 32.59  ? 474 GLN C CD  1 
ATOM   7428  O OE1 . GLN C 1 272 ? -27.705 -21.711 42.570 1.00 33.83  ? 474 GLN C OE1 1 
ATOM   7429  N NE2 . GLN C 1 272 ? -27.713 -23.651 41.462 1.00 34.27  ? 474 GLN C NE2 1 
ATOM   7430  N N   . GLY C 1 273 ? -32.926 -20.366 43.739 1.00 28.93  ? 475 GLY C N   1 
ATOM   7431  C CA  . GLY C 1 273 ? -33.460 -19.491 44.763 1.00 27.79  ? 475 GLY C CA  1 
ATOM   7432  C C   . GLY C 1 273 ? -32.359 -18.677 45.417 1.00 28.55  ? 475 GLY C C   1 
ATOM   7433  O O   . GLY C 1 273 ? -31.223 -19.129 45.561 1.00 29.00  ? 475 GLY C O   1 
ATOM   7434  N N   . ARG C 1 274 ? -32.705 -17.455 45.809 1.00 27.01  ? 476 ARG C N   1 
ATOM   7435  C CA  . ARG C 1 274 ? -31.769 -16.542 46.441 1.00 26.76  ? 476 ARG C CA  1 
ATOM   7436  C C   . ARG C 1 274 ? -32.461 -15.811 47.580 1.00 26.50  ? 476 ARG C C   1 
ATOM   7437  O O   . ARG C 1 274 ? -33.653 -15.504 47.509 1.00 27.59  ? 476 ARG C O   1 
ATOM   7438  C CB  . ARG C 1 274 ? -31.210 -15.537 45.436 1.00 19.55  ? 476 ARG C CB  1 
ATOM   7439  C CG  . ARG C 1 274 ? -30.328 -16.162 44.387 1.00 21.10  ? 476 ARG C CG  1 
ATOM   7440  C CD  . ARG C 1 274 ? -29.843 -15.144 43.384 1.00 22.45  ? 476 ARG C CD  1 
ATOM   7441  N NE  . ARG C 1 274 ? -28.982 -15.759 42.384 1.00 26.68  ? 476 ARG C NE  1 
ATOM   7442  C CZ  . ARG C 1 274 ? -29.431 -16.413 41.319 1.00 27.55  ? 476 ARG C CZ  1 
ATOM   7443  N NH1 . ARG C 1 274 ? -30.734 -16.540 41.116 1.00 30.36  ? 476 ARG C NH1 1 
ATOM   7444  N NH2 . ARG C 1 274 ? -28.577 -16.942 40.459 1.00 29.65  ? 476 ARG C NH2 1 
ATOM   7445  N N   . ASN C 1 275 ? -31.702 -15.553 48.641 1.00 26.03  ? 477 ASN C N   1 
ATOM   7446  C CA  . ASN C 1 275 ? -32.211 -14.862 49.816 1.00 25.40  ? 477 ASN C CA  1 
ATOM   7447  C C   . ASN C 1 275 ? -32.210 -13.346 49.689 1.00 25.04  ? 477 ASN C C   1 
ATOM   7448  O O   . ASN C 1 275 ? -32.932 -12.683 50.439 1.00 24.06  ? 477 ASN C O   1 
ATOM   7449  C CB  . ASN C 1 275 ? -31.395 -15.263 51.046 1.00 28.47  ? 477 ASN C CB  1 
ATOM   7450  C CG  . ASN C 1 275 ? -31.755 -16.632 51.560 1.00 29.99  ? 477 ASN C CG  1 
ATOM   7451  O OD1 . ASN C 1 275 ? -32.892 -17.071 51.427 1.00 32.31  ? 477 ASN C OD1 1 
ATOM   7452  N ND2 . ASN C 1 275 ? -30.781 -17.327 52.127 1.00 30.33  ? 477 ASN C ND2 1 
ATOM   7453  N N   . TYR C 1 276 ? -31.419 -12.779 48.782 1.00 20.55  ? 478 TYR C N   1 
ATOM   7454  C CA  . TYR C 1 276 ? -31.259 -11.334 48.718 1.00 21.61  ? 478 TYR C CA  1 
ATOM   7455  C C   . TYR C 1 276 ? -31.201 -10.896 47.264 1.00 22.69  ? 478 TYR C C   1 
ATOM   7456  O O   . TYR C 1 276 ? -30.846 -11.678 46.380 1.00 24.82  ? 478 TYR C O   1 
ATOM   7457  C CB  . TYR C 1 276 ? -30.006 -10.887 49.476 1.00 21.11  ? 478 TYR C CB  1 
ATOM   7458  C CG  . TYR C 1 276 ? -30.084 -11.211 50.944 1.00 23.32  ? 478 TYR C CG  1 
ATOM   7459  C CD1 . TYR C 1 276 ? -30.696 -10.342 51.830 1.00 23.82  ? 478 TYR C CD1 1 
ATOM   7460  C CD2 . TYR C 1 276 ? -29.567 -12.396 51.442 1.00 22.51  ? 478 TYR C CD2 1 
ATOM   7461  C CE1 . TYR C 1 276 ? -30.783 -10.639 53.167 1.00 24.06  ? 478 TYR C CE1 1 
ATOM   7462  C CE2 . TYR C 1 276 ? -29.652 -12.705 52.781 1.00 24.36  ? 478 TYR C CE2 1 
ATOM   7463  C CZ  . TYR C 1 276 ? -30.263 -11.821 53.639 1.00 25.18  ? 478 TYR C CZ  1 
ATOM   7464  O OH  . TYR C 1 276 ? -30.352 -12.111 54.979 1.00 26.73  ? 478 TYR C OH  1 
ATOM   7465  N N   . ILE C 1 277 ? -31.556 -9.637  47.031 1.00 18.61  ? 479 ILE C N   1 
ATOM   7466  C CA  . ILE C 1 277 ? -31.715 -9.101  45.680 1.00 18.00  ? 479 ILE C CA  1 
ATOM   7467  C C   . ILE C 1 277 ? -31.098 -7.709  45.635 1.00 19.16  ? 479 ILE C C   1 
ATOM   7468  O O   . ILE C 1 277 ? -30.987 -7.034  46.669 1.00 19.53  ? 479 ILE C O   1 
ATOM   7469  C CB  . ILE C 1 277 ? -33.201 -9.079  45.252 1.00 20.53  ? 479 ILE C CB  1 
ATOM   7470  C CG1 . ILE C 1 277 ? -34.028 -8.258  46.237 1.00 18.90  ? 479 ILE C CG1 1 
ATOM   7471  C CG2 . ILE C 1 277 ? -33.748 -10.483 45.145 1.00 19.35  ? 479 ILE C CG2 1 
ATOM   7472  C CD1 . ILE C 1 277 ? -35.453 -8.066  45.808 1.00 17.41  ? 479 ILE C CD1 1 
ATOM   7473  N N   . PRO C 1 278 ? -30.678 -7.251  44.454 1.00 17.94  ? 480 PRO C N   1 
ATOM   7474  C CA  . PRO C 1 278 ? -29.919 -5.999  44.376 1.00 18.38  ? 480 PRO C CA  1 
ATOM   7475  C C   . PRO C 1 278 ? -30.743 -4.783  44.761 1.00 19.06  ? 480 PRO C C   1 
ATOM   7476  O O   . PRO C 1 278 ? -31.974 -4.818  44.804 1.00 18.54  ? 480 PRO C O   1 
ATOM   7477  C CB  . PRO C 1 278 ? -29.499 -5.935  42.904 1.00 18.37  ? 480 PRO C CB  1 
ATOM   7478  C CG  . PRO C 1 278 ? -30.523 -6.713  42.203 1.00 18.82  ? 480 PRO C CG  1 
ATOM   7479  C CD  . PRO C 1 278 ? -30.850 -7.847  43.120 1.00 17.60  ? 480 PRO C CD  1 
ATOM   7480  N N   . GLY C 1 279 ? -30.036 -3.690  45.034 1.00 16.50  ? 481 GLY C N   1 
ATOM   7481  C CA  . GLY C 1 279 ? -30.638 -2.482  45.541 1.00 17.57  ? 481 GLY C CA  1 
ATOM   7482  C C   . GLY C 1 279 ? -31.523 -1.755  44.551 1.00 18.44  ? 481 GLY C C   1 
ATOM   7483  O O   . GLY C 1 279 ? -31.648 -2.136  43.384 1.00 18.99  ? 481 GLY C O   1 
ATOM   7484  N N   . PRO C 1 280 ? -32.149 -0.674  45.012 1.00 19.31  ? 482 PRO C N   1 
ATOM   7485  C CA  . PRO C 1 280 ? -33.099 0.056   44.166 1.00 19.86  ? 482 PRO C CA  1 
ATOM   7486  C C   . PRO C 1 280 ? -32.409 0.755   43.004 1.00 20.86  ? 482 PRO C C   1 
ATOM   7487  O O   . PRO C 1 280 ? -31.197 0.976   43.017 1.00 20.96  ? 482 PRO C O   1 
ATOM   7488  C CB  . PRO C 1 280 ? -33.720 1.063   45.136 1.00 21.40  ? 482 PRO C CB  1 
ATOM   7489  C CG  . PRO C 1 280 ? -32.672 1.265   46.162 1.00 21.27  ? 482 PRO C CG  1 
ATOM   7490  C CD  . PRO C 1 280 ? -32.033 -0.069  46.348 1.00 20.96  ? 482 PRO C CD  1 
ATOM   7491  N N   . SER C 1 281 ? -33.203 1.113   41.996 1.00 21.02  ? 483 SER C N   1 
ATOM   7492  C CA  . SER C 1 281 ? -32.688 1.750   40.794 1.00 21.88  ? 483 SER C CA  1 
ATOM   7493  C C   . SER C 1 281 ? -33.679 2.788   40.293 1.00 21.30  ? 483 SER C C   1 
ATOM   7494  O O   . SER C 1 281 ? -34.891 2.642   40.460 1.00 21.74  ? 483 SER C O   1 
ATOM   7495  C CB  . SER C 1 281 ? -32.417 0.728   39.685 1.00 19.35  ? 483 SER C CB  1 
ATOM   7496  O OG  . SER C 1 281 ? -33.612 0.106   39.255 1.00 21.79  ? 483 SER C OG  1 
ATOM   7497  N N   . TYR C 1 282 ? -33.145 3.863   39.716 1.00 23.84  ? 484 TYR C N   1 
ATOM   7498  C CA  . TYR C 1 282 ? -33.927 4.874   39.014 1.00 21.87  ? 484 TYR C CA  1 
ATOM   7499  C C   . TYR C 1 282 ? -33.163 5.189   37.735 1.00 21.29  ? 484 TYR C C   1 
ATOM   7500  O O   . TYR C 1 282 ? -32.104 5.816   37.801 1.00 21.56  ? 484 TYR C O   1 
ATOM   7501  C CB  . TYR C 1 282 ? -34.061 6.116   39.900 1.00 25.13  ? 484 TYR C CB  1 
ATOM   7502  C CG  . TYR C 1 282 ? -35.018 7.194   39.463 1.00 24.07  ? 484 TYR C CG  1 
ATOM   7503  C CD1 . TYR C 1 282 ? -36.352 7.149   39.835 1.00 23.93  ? 484 TYR C CD1 1 
ATOM   7504  C CD2 . TYR C 1 282 ? -34.590 8.264   38.697 1.00 23.39  ? 484 TYR C CD2 1 
ATOM   7505  C CE1 . TYR C 1 282 ? -37.229 8.138   39.462 1.00 23.03  ? 484 TYR C CE1 1 
ATOM   7506  C CE2 . TYR C 1 282 ? -35.461 9.252   38.310 1.00 22.48  ? 484 TYR C CE2 1 
ATOM   7507  C CZ  . TYR C 1 282 ? -36.781 9.184   38.696 1.00 22.98  ? 484 TYR C CZ  1 
ATOM   7508  O OH  . TYR C 1 282 ? -37.660 10.167  38.313 1.00 22.67  ? 484 TYR C OH  1 
ATOM   7509  N N   . ARG C 1 283 ? -33.698 4.806   36.574 1.00 21.67  ? 485 ARG C N   1 
ATOM   7510  C CA  . ARG C 1 283 ? -32.820 4.697   35.411 1.00 21.16  ? 485 ARG C CA  1 
ATOM   7511  C C   . ARG C 1 283 ? -32.345 6.070   34.930 1.00 21.24  ? 485 ARG C C   1 
ATOM   7512  O O   . ARG C 1 283 ? -33.044 7.078   35.049 1.00 20.83  ? 485 ARG C O   1 
ATOM   7513  C CB  . ARG C 1 283 ? -33.491 3.954   34.246 1.00 21.23  ? 485 ARG C CB  1 
ATOM   7514  C CG  . ARG C 1 283 ? -32.477 3.725   33.119 1.00 22.83  ? 485 ARG C CG  1 
ATOM   7515  C CD  . ARG C 1 283 ? -32.957 3.212   31.772 1.00 22.27  ? 485 ARG C CD  1 
ATOM   7516  N NE  . ARG C 1 283 ? -33.388 1.825   31.742 1.00 22.94  ? 485 ARG C NE  1 
ATOM   7517  C CZ  . ARG C 1 283 ? -33.710 1.190   30.620 1.00 22.37  ? 485 ARG C CZ  1 
ATOM   7518  N NH1 . ARG C 1 283 ? -33.612 1.816   29.461 1.00 21.38  ? 485 ARG C NH1 1 
ATOM   7519  N NH2 . ARG C 1 283 ? -34.100 -0.072  30.650 1.00 24.58  ? 485 ARG C NH2 1 
ATOM   7520  N N   . GLN C 1 284 ? -31.124 6.087   34.386 1.00 19.55  ? 486 GLN C N   1 
ATOM   7521  C CA  . GLN C 1 284 ? -30.513 7.225   33.716 1.00 20.10  ? 486 GLN C CA  1 
ATOM   7522  C C   . GLN C 1 284 ? -30.373 6.896   32.237 1.00 20.90  ? 486 GLN C C   1 
ATOM   7523  O O   . GLN C 1 284 ? -30.313 5.728   31.851 1.00 20.52  ? 486 GLN C O   1 
ATOM   7524  C CB  . GLN C 1 284 ? -29.116 7.532   34.281 1.00 18.56  ? 486 GLN C CB  1 
ATOM   7525  C CG  . GLN C 1 284 ? -29.058 7.964   35.733 1.00 20.44  ? 486 GLN C CG  1 
ATOM   7526  C CD  . GLN C 1 284 ? -29.727 9.293   35.978 1.00 22.30  ? 486 GLN C CD  1 
ATOM   7527  O OE1 . GLN C 1 284 ? -29.620 10.207  35.164 1.00 23.50  ? 486 GLN C OE1 1 
ATOM   7528  N NE2 . GLN C 1 284 ? -30.415 9.414   37.107 1.00 23.18  ? 486 GLN C NE2 1 
ATOM   7529  N N   . GLN C 1 285 ? -30.325 7.933   31.417 1.00 17.72  ? 487 GLN C N   1 
ATOM   7530  C CA  . GLN C 1 285 ? -30.135 7.764   29.993 1.00 17.78  ? 487 GLN C CA  1 
ATOM   7531  C C   . GLN C 1 285 ? -28.648 7.560   29.813 1.00 18.21  ? 487 GLN C C   1 
ATOM   7532  O O   . GLN C 1 285 ? -27.861 8.182   30.516 1.00 18.30  ? 487 GLN C O   1 
ATOM   7533  C CB  . GLN C 1 285 ? -30.559 9.029   29.259 1.00 20.51  ? 487 GLN C CB  1 
ATOM   7534  C CG  . GLN C 1 285 ? -30.491 8.913   27.755 1.00 20.42  ? 487 GLN C CG  1 
ATOM   7535  C CD  . GLN C 1 285 ? -31.370 7.802   27.250 1.00 20.95  ? 487 GLN C CD  1 
ATOM   7536  O OE1 . GLN C 1 285 ? -30.894 6.842   26.656 1.00 18.29  ? 487 GLN C OE1 1 
ATOM   7537  N NE2 . GLN C 1 285 ? -32.662 7.912   27.509 1.00 21.12  ? 487 GLN C NE2 1 
ATOM   7538  N N   . ARG C 1 286 ? -28.235 6.715   28.880 1.00 15.74  ? 488 ARG C N   1 
ATOM   7539  C CA  . ARG C 1 286 ? -26.804 6.520   28.715 1.00 15.69  ? 488 ARG C CA  1 
ATOM   7540  C C   . ARG C 1 286 ? -26.252 7.285   27.521 1.00 15.63  ? 488 ARG C C   1 
ATOM   7541  O O   . ARG C 1 286 ? -26.777 7.214   26.420 1.00 17.30  ? 488 ARG C O   1 
ATOM   7542  C CB  . ARG C 1 286 ? -26.411 5.039   28.705 1.00 13.92  ? 488 ARG C CB  1 
ATOM   7543  C CG  . ARG C 1 286 ? -26.302 4.372   27.350 1.00 15.02  ? 488 ARG C CG  1 
ATOM   7544  C CD  . ARG C 1 286 ? -25.213 3.321   27.412 1.00 17.34  ? 488 ARG C CD  1 
ATOM   7545  N NE  . ARG C 1 286 ? -25.519 2.106   26.667 1.00 20.48  ? 488 ARG C NE  1 
ATOM   7546  C CZ  . ARG C 1 286 ? -25.756 2.061   25.364 1.00 23.15  ? 488 ARG C CZ  1 
ATOM   7547  N NH1 . ARG C 1 286 ? -25.760 3.172   24.650 1.00 21.01  ? 488 ARG C NH1 1 
ATOM   7548  N NH2 . ARG C 1 286 ? -26.005 0.906   24.777 1.00 26.33  ? 488 ARG C NH2 1 
ATOM   7549  N N   . VAL C 1 287 ? -25.187 8.032   27.775 1.00 13.84  ? 489 VAL C N   1 
ATOM   7550  C CA  . VAL C 1 287 ? -24.547 8.848   26.768 1.00 13.43  ? 489 VAL C CA  1 
ATOM   7551  C C   . VAL C 1 287 ? -23.257 8.200   26.330 1.00 13.95  ? 489 VAL C C   1 
ATOM   7552  O O   . VAL C 1 287 ? -22.435 7.837   27.151 1.00 14.99  ? 489 VAL C O   1 
ATOM   7553  C CB  . VAL C 1 287 ? -24.201 10.224  27.346 1.00 14.56  ? 489 VAL C CB  1 
ATOM   7554  C CG1 . VAL C 1 287 ? -23.566 11.104  26.290 1.00 13.49  ? 489 VAL C CG1 1 
ATOM   7555  C CG2 . VAL C 1 287 ? -25.441 10.877  27.921 1.00 15.40  ? 489 VAL C CG2 1 
ATOM   7556  N N   . SER C 1 288 ? -23.083 8.044   25.028 1.00 12.31  ? 490 SER C N   1 
ATOM   7557  C CA  . SER C 1 288 ? -21.874 7.440   24.507 1.00 12.76  ? 490 SER C CA  1 
ATOM   7558  C C   . SER C 1 288 ? -20.790 8.479   24.332 1.00 13.66  ? 490 SER C C   1 
ATOM   7559  O O   . SER C 1 288 ? -21.049 9.596   23.924 1.00 12.24  ? 490 SER C O   1 
ATOM   7560  C CB  . SER C 1 288 ? -22.138 6.756   23.175 1.00 13.54  ? 490 SER C CB  1 
ATOM   7561  O OG  . SER C 1 288 ? -20.966 6.117   22.720 1.00 13.61  ? 490 SER C OG  1 
ATOM   7562  N N   . THR C 1 289 ? -19.572 8.089   24.656 1.00 10.61  ? 491 THR C N   1 
ATOM   7563  C CA  . THR C 1 289 ? -18.402 8.948   24.541 1.00 13.14  ? 491 THR C CA  1 
ATOM   7564  C C   . THR C 1 289 ? -18.099 9.294   23.090 1.00 14.97  ? 491 THR C C   1 
ATOM   7565  O O   . THR C 1 289 ? -17.725 10.431  22.783 1.00 16.07  ? 491 THR C O   1 
ATOM   7566  C CB  . THR C 1 289 ? -17.209 8.264   25.195 1.00 12.78  ? 491 THR C CB  1 
ATOM   7567  O OG1 . THR C 1 289 ? -17.356 8.295   26.622 1.00 16.18  ? 491 THR C OG1 1 
ATOM   7568  C CG2 . THR C 1 289 ? -15.945 8.905   24.770 1.00 11.67  ? 491 THR C CG2 1 
ATOM   7569  N N   . THR C 1 290 ? -18.249 8.334   22.183 1.00 14.42  ? 492 THR C N   1 
ATOM   7570  C CA  . THR C 1 290 ? -18.068 8.610   20.762 1.00 15.51  ? 492 THR C CA  1 
ATOM   7571  C C   . THR C 1 290 ? -19.304 9.368   20.304 1.00 15.24  ? 492 THR C C   1 
ATOM   7572  O O   . THR C 1 290 ? -20.421 8.853   20.365 1.00 15.36  ? 492 THR C O   1 
ATOM   7573  C CB  . THR C 1 290 ? -17.873 7.317   19.979 1.00 15.21  ? 492 THR C CB  1 
ATOM   7574  O OG1 . THR C 1 290 ? -16.754 6.603   20.512 1.00 17.57  ? 492 THR C OG1 1 
ATOM   7575  C CG2 . THR C 1 290 ? -17.601 7.621   18.528 1.00 15.05  ? 492 THR C CG2 1 
ATOM   7576  N N   . VAL C 1 291 ? -19.106 10.592  19.814 1.00 17.66  ? 493 VAL C N   1 
ATOM   7577  C CA  . VAL C 1 291 ? -20.231 11.504  19.625 1.00 17.43  ? 493 VAL C CA  1 
ATOM   7578  C C   . VAL C 1 291 ? -21.124 11.034  18.489 1.00 16.92  ? 493 VAL C C   1 
ATOM   7579  O O   . VAL C 1 291 ? -22.326 11.320  18.464 1.00 16.79  ? 493 VAL C O   1 
ATOM   7580  C CB  . VAL C 1 291 ? -19.724 12.937  19.386 1.00 18.74  ? 493 VAL C CB  1 
ATOM   7581  C CG1 . VAL C 1 291 ? -18.958 13.429  20.591 1.00 20.40  ? 493 VAL C CG1 1 
ATOM   7582  C CG2 . VAL C 1 291 ? -18.860 12.994  18.150 1.00 18.61  ? 493 VAL C CG2 1 
ATOM   7583  N N   . THR C 1 292 ? -20.557 10.301  17.535 1.00 20.10  ? 494 THR C N   1 
ATOM   7584  C CA  . THR C 1 292 ? -21.348 9.877   16.390 1.00 19.53  ? 494 THR C CA  1 
ATOM   7585  C C   . THR C 1 292 ? -22.287 8.735   16.746 1.00 19.31  ? 494 THR C C   1 
ATOM   7586  O O   . THR C 1 292 ? -23.170 8.393   15.953 1.00 19.42  ? 494 THR C O   1 
ATOM   7587  C CB  . THR C 1 292 ? -20.431 9.478   15.239 1.00 24.30  ? 494 THR C CB  1 
ATOM   7588  O OG1 . THR C 1 292 ? -21.219 9.227   14.071 1.00 24.56  ? 494 THR C OG1 1 
ATOM   7589  C CG2 . THR C 1 292 ? -19.648 8.234   15.592 1.00 23.34  ? 494 THR C CG2 1 
ATOM   7590  N N   . GLN C 1 293 ? -22.113 8.130   17.922 1.00 17.88  ? 495 GLN C N   1 
ATOM   7591  C CA  . GLN C 1 293 ? -23.014 7.066   18.348 1.00 17.04  ? 495 GLN C CA  1 
ATOM   7592  C C   . GLN C 1 293 ? -24.197 7.621   19.128 1.00 16.63  ? 495 GLN C C   1 
ATOM   7593  O O   . GLN C 1 293 ? -25.157 6.898   19.409 1.00 17.05  ? 495 GLN C O   1 
ATOM   7594  C CB  . GLN C 1 293 ? -22.252 6.043   19.187 1.00 12.13  ? 495 GLN C CB  1 
ATOM   7595  C CG  . GLN C 1 293 ? -21.176 5.311   18.417 1.00 14.61  ? 495 GLN C CG  1 
ATOM   7596  C CD  . GLN C 1 293 ? -20.395 4.362   19.288 1.00 16.48  ? 495 GLN C CD  1 
ATOM   7597  O OE1 . GLN C 1 293 ? -20.359 4.510   20.507 1.00 18.26  ? 495 GLN C OE1 1 
ATOM   7598  N NE2 . GLN C 1 293 ? -19.752 3.384   18.668 1.00 17.83  ? 495 GLN C NE2 1 
ATOM   7599  N N   . ASN C 1 294 ? -24.150 8.897   19.471 1.00 18.44  ? 496 ASN C N   1 
ATOM   7600  C CA  . ASN C 1 294 ? -25.242 9.526   20.198 1.00 17.76  ? 496 ASN C CA  1 
ATOM   7601  C C   . ASN C 1 294 ? -26.315 9.970   19.224 1.00 18.30  ? 496 ASN C C   1 
ATOM   7602  O O   . ASN C 1 294 ? -26.080 10.037  18.027 1.00 18.23  ? 496 ASN C O   1 
ATOM   7603  C CB  . ASN C 1 294 ? -24.740 10.751  20.952 1.00 15.82  ? 496 ASN C CB  1 
ATOM   7604  C CG  . ASN C 1 294 ? -23.823 10.399  22.093 1.00 15.85  ? 496 ASN C CG  1 
ATOM   7605  O OD1 . ASN C 1 294 ? -23.988 9.381   22.742 1.00 14.59  ? 496 ASN C OD1 1 
ATOM   7606  N ND2 . ASN C 1 294 ? -22.854 11.253  22.349 1.00 17.14  ? 496 ASN C ND2 1 
ATOM   7607  N N   . ASN C 1 295 ? -27.506 10.252  19.729 1.00 20.73  ? 497 ASN C N   1 
ATOM   7608  C CA  . ASN C 1 295 ? -28.576 10.730  18.871 1.00 21.49  ? 497 ASN C CA  1 
ATOM   7609  C C   . ASN C 1 295 ? -28.252 12.156  18.445 1.00 22.37  ? 497 ASN C C   1 
ATOM   7610  O O   . ASN C 1 295 ? -27.691 12.921  19.215 1.00 22.11  ? 497 ASN C O   1 
ATOM   7611  C CB  . ASN C 1 295 ? -29.918 10.686  19.594 1.00 23.16  ? 497 ASN C CB  1 
ATOM   7612  C CG  . ASN C 1 295 ? -31.080 10.965  18.672 1.00 24.39  ? 497 ASN C CG  1 
ATOM   7613  O OD1 . ASN C 1 295 ? -31.336 10.219  17.735 1.00 24.83  ? 497 ASN C OD1 1 
ATOM   7614  N ND2 . ASN C 1 295 ? -31.794 12.044  18.938 1.00 24.63  ? 497 ASN C ND2 1 
ATOM   7615  N N   . ASN C 1 296 ? -28.598 12.518  17.219 1.00 24.57  ? 498 ASN C N   1 
ATOM   7616  C CA  . ASN C 1 296 ? -28.335 13.862  16.739 1.00 25.72  ? 498 ASN C CA  1 
ATOM   7617  C C   . ASN C 1 296 ? -29.459 14.823  17.113 1.00 26.43  ? 498 ASN C C   1 
ATOM   7618  O O   . ASN C 1 296 ? -30.218 15.266  16.261 1.00 26.99  ? 498 ASN C O   1 
ATOM   7619  C CB  . ASN C 1 296 ? -28.123 13.847  15.230 1.00 28.60  ? 498 ASN C CB  1 
ATOM   7620  C CG  . ASN C 1 296 ? -27.708 15.192  14.685 1.00 28.71  ? 498 ASN C CG  1 
ATOM   7621  O OD1 . ASN C 1 296 ? -27.246 16.057  15.417 1.00 28.42  ? 498 ASN C OD1 1 
ATOM   7622  N ND2 . ASN C 1 296 ? -27.864 15.370  13.389 1.00 29.67  ? 498 ASN C ND2 1 
ATOM   7623  N N   . SER C 1 297 ? -29.567 15.121  18.401 1.00 25.86  ? 499 SER C N   1 
ATOM   7624  C CA  . SER C 1 297 ? -30.565 16.036  18.929 1.00 26.74  ? 499 SER C CA  1 
ATOM   7625  C C   . SER C 1 297 ? -30.102 16.506  20.292 1.00 26.89  ? 499 SER C C   1 
ATOM   7626  O O   . SER C 1 297 ? -29.220 15.903  20.894 1.00 26.57  ? 499 SER C O   1 
ATOM   7627  C CB  . SER C 1 297 ? -31.920 15.357  19.059 1.00 27.36  ? 499 SER C CB  1 
ATOM   7628  O OG  . SER C 1 297 ? -32.013 14.644  20.276 1.00 28.25  ? 499 SER C OG  1 
ATOM   7629  N N   . GLU C 1 298 ? -30.696 17.573  20.800 1.00 27.03  ? 500 GLU C N   1 
ATOM   7630  C CA  . GLU C 1 298 ? -30.299 18.046  22.108 1.00 27.54  ? 500 GLU C CA  1 
ATOM   7631  C C   . GLU C 1 298 ? -31.156 17.340  23.139 1.00 26.77  ? 500 GLU C C   1 
ATOM   7632  O O   . GLU C 1 298 ? -32.347 17.616  23.254 1.00 27.18  ? 500 GLU C O   1 
ATOM   7633  C CB  . GLU C 1 298 ? -30.521 19.546  22.206 1.00 24.24  ? 500 GLU C CB  1 
ATOM   7634  C CG  . GLU C 1 298 ? -30.358 20.081  23.611 1.00 28.31  ? 500 GLU C CG  1 
ATOM   7635  C CD  . GLU C 1 298 ? -28.924 20.027  24.083 1.00 30.67  ? 500 GLU C CD  1 
ATOM   7636  O OE1 . GLU C 1 298 ? -28.047 20.569  23.383 1.00 31.93  ? 500 GLU C OE1 1 
ATOM   7637  O OE2 . GLU C 1 298 ? -28.679 19.453  25.160 1.00 30.78  ? 500 GLU C OE2 1 
ATOM   7638  N N   . PHE C 1 299 ? -30.554 16.411  23.873 1.00 26.74  ? 501 PHE C N   1 
ATOM   7639  C CA  . PHE C 1 299 ? -31.284 15.667  24.891 1.00 25.67  ? 501 PHE C CA  1 
ATOM   7640  C C   . PHE C 1 299 ? -30.746 15.791  26.310 1.00 25.21  ? 501 PHE C C   1 
ATOM   7641  O O   . PHE C 1 299 ? -31.185 15.070  27.190 1.00 25.43  ? 501 PHE C O   1 
ATOM   7642  C CB  . PHE C 1 299 ? -31.427 14.193  24.497 1.00 24.58  ? 501 PHE C CB  1 
ATOM   7643  C CG  . PHE C 1 299 ? -30.130 13.443  24.446 1.00 23.75  ? 501 PHE C CG  1 
ATOM   7644  C CD1 . PHE C 1 299 ? -29.609 12.865  25.585 1.00 23.37  ? 501 PHE C CD1 1 
ATOM   7645  C CD2 . PHE C 1 299 ? -29.446 13.302  23.259 1.00 23.43  ? 501 PHE C CD2 1 
ATOM   7646  C CE1 . PHE C 1 299 ? -28.422 12.170  25.543 1.00 22.90  ? 501 PHE C CE1 1 
ATOM   7647  C CE2 . PHE C 1 299 ? -28.257 12.612  23.207 1.00 22.83  ? 501 PHE C CE2 1 
ATOM   7648  C CZ  . PHE C 1 299 ? -27.744 12.042  24.350 1.00 22.56  ? 501 PHE C CZ  1 
ATOM   7649  N N   . ALA C 1 300 ? -29.844 16.728  26.560 1.00 25.69  ? 502 ALA C N   1 
ATOM   7650  C CA  . ALA C 1 300 ? -29.267 16.840  27.894 1.00 24.74  ? 502 ALA C CA  1 
ATOM   7651  C C   . ALA C 1 300 ? -30.319 17.126  28.955 1.00 24.55  ? 502 ALA C C   1 
ATOM   7652  O O   . ALA C 1 300 ? -30.250 16.590  30.054 1.00 24.47  ? 502 ALA C O   1 
ATOM   7653  C CB  . ALA C 1 300 ? -28.173 17.890  27.925 1.00 23.25  ? 502 ALA C CB  1 
ATOM   7654  N N   . TRP C 1 301 ? -31.283 17.981  28.647 1.00 26.38  ? 503 TRP C N   1 
ATOM   7655  C CA  . TRP C 1 301 ? -32.333 18.253  29.609 1.00 26.92  ? 503 TRP C CA  1 
ATOM   7656  C C   . TRP C 1 301 ? -33.574 17.462  29.249 1.00 26.60  ? 503 TRP C C   1 
ATOM   7657  O O   . TRP C 1 301 ? -34.228 16.906  30.118 1.00 26.58  ? 503 TRP C O   1 
ATOM   7658  C CB  . TRP C 1 301 ? -32.668 19.733  29.697 1.00 28.03  ? 503 TRP C CB  1 
ATOM   7659  C CG  . TRP C 1 301 ? -33.828 19.974  30.601 1.00 31.30  ? 503 TRP C CG  1 
ATOM   7660  C CD1 . TRP C 1 301 ? -35.079 20.363  30.238 1.00 32.16  ? 503 TRP C CD1 1 
ATOM   7661  C CD2 . TRP C 1 301 ? -33.857 19.802  32.020 1.00 32.88  ? 503 TRP C CD2 1 
ATOM   7662  N NE1 . TRP C 1 301 ? -35.881 20.462  31.342 1.00 32.80  ? 503 TRP C NE1 1 
ATOM   7663  C CE2 . TRP C 1 301 ? -35.153 20.124  32.451 1.00 33.16  ? 503 TRP C CE2 1 
ATOM   7664  C CE3 . TRP C 1 301 ? -32.909 19.420  32.969 1.00 33.65  ? 503 TRP C CE3 1 
ATOM   7665  C CZ2 . TRP C 1 301 ? -35.526 20.074  33.789 1.00 33.94  ? 503 TRP C CZ2 1 
ATOM   7666  C CZ3 . TRP C 1 301 ? -33.280 19.370  34.292 1.00 34.26  ? 503 TRP C CZ3 1 
ATOM   7667  C CH2 . TRP C 1 301 ? -34.577 19.695  34.691 1.00 34.46  ? 503 TRP C CH2 1 
ATOM   7668  N N   . PRO C 1 302 ? -33.921 17.420  27.960 1.00 26.65  ? 504 PRO C N   1 
ATOM   7669  C CA  . PRO C 1 302 ? -35.116 16.636  27.591 1.00 26.38  ? 504 PRO C CA  1 
ATOM   7670  C C   . PRO C 1 302 ? -35.035 15.161  27.950 1.00 26.82  ? 504 PRO C C   1 
ATOM   7671  O O   . PRO C 1 302 ? -36.007 14.605  28.477 1.00 28.39  ? 504 PRO C O   1 
ATOM   7672  C CB  . PRO C 1 302 ? -35.204 16.838  26.074 1.00 26.09  ? 504 PRO C CB  1 
ATOM   7673  C CG  . PRO C 1 302 ? -34.564 18.135  25.843 1.00 25.41  ? 504 PRO C CG  1 
ATOM   7674  C CD  . PRO C 1 302 ? -33.430 18.200  26.810 1.00 26.81  ? 504 PRO C CD  1 
ATOM   7675  N N   . GLY C 1 303 ? -33.907 14.506  27.675 1.00 25.21  ? 505 GLY C N   1 
ATOM   7676  C CA  . GLY C 1 303 ? -33.795 13.087  27.965 1.00 25.51  ? 505 GLY C CA  1 
ATOM   7677  C C   . GLY C 1 303 ? -33.252 12.801  29.349 1.00 25.15  ? 505 GLY C C   1 
ATOM   7678  O O   . GLY C 1 303 ? -32.694 11.728  29.590 1.00 26.08  ? 505 GLY C O   1 
ATOM   7679  N N   . ALA C 1 304 ? -33.394 13.749  30.269 1.00 26.43  ? 506 ALA C N   1 
ATOM   7680  C CA  . ALA C 1 304 ? -32.803 13.601  31.590 1.00 25.20  ? 506 ALA C CA  1 
ATOM   7681  C C   . ALA C 1 304 ? -33.801 13.019  32.581 1.00 24.53  ? 506 ALA C C   1 
ATOM   7682  O O   . ALA C 1 304 ? -34.998 13.308  32.526 1.00 25.38  ? 506 ALA C O   1 
ATOM   7683  C CB  . ALA C 1 304 ? -32.305 14.951  32.093 1.00 25.71  ? 506 ALA C CB  1 
ATOM   7684  N N   . SER C 1 305 ? -33.298 12.187  33.487 1.00 26.55  ? 507 SER C N   1 
ATOM   7685  C CA  . SER C 1 305 ? -34.095 11.699  34.601 1.00 25.39  ? 507 SER C CA  1 
ATOM   7686  C C   . SER C 1 305 ? -34.239 12.797  35.642 1.00 24.34  ? 507 SER C C   1 
ATOM   7687  O O   . SER C 1 305 ? -33.255 13.430  36.030 1.00 23.84  ? 507 SER C O   1 
ATOM   7688  C CB  . SER C 1 305 ? -33.441 10.469  35.226 1.00 22.73  ? 507 SER C CB  1 
ATOM   7689  O OG  . SER C 1 305 ? -33.372 9.399   34.303 1.00 24.72  ? 507 SER C OG  1 
ATOM   7690  N N   . SER C 1 306 ? -35.464 13.019  36.105 1.00 25.37  ? 508 SER C N   1 
ATOM   7691  C CA  . SER C 1 306 ? -35.710 14.151  36.984 1.00 24.43  ? 508 SER C CA  1 
ATOM   7692  C C   . SER C 1 306 ? -36.822 13.818  37.963 1.00 23.62  ? 508 SER C C   1 
ATOM   7693  O O   . SER C 1 306 ? -37.581 12.867  37.771 1.00 24.15  ? 508 SER C O   1 
ATOM   7694  C CB  . SER C 1 306 ? -36.068 15.405  36.184 1.00 26.74  ? 508 SER C CB  1 
ATOM   7695  O OG  . SER C 1 306 ? -37.276 15.219  35.474 1.00 26.83  ? 508 SER C OG  1 
ATOM   7696  N N   . TRP C 1 307 ? -36.898 14.616  39.023 1.00 27.72  ? 509 TRP C N   1 
ATOM   7697  C CA  . TRP C 1 307 ? -37.975 14.535  39.993 1.00 27.16  ? 509 TRP C CA  1 
ATOM   7698  C C   . TRP C 1 307 ? -38.631 15.897  40.161 1.00 26.74  ? 509 TRP C C   1 
ATOM   7699  O O   . TRP C 1 307 ? -38.004 16.941  39.954 1.00 25.13  ? 509 TRP C O   1 
ATOM   7700  C CB  . TRP C 1 307 ? -37.483 14.013  41.347 1.00 24.88  ? 509 TRP C CB  1 
ATOM   7701  C CG  . TRP C 1 307 ? -36.283 14.710  41.910 1.00 25.55  ? 509 TRP C CG  1 
ATOM   7702  C CD1 . TRP C 1 307 ? -34.980 14.372  41.710 1.00 26.01  ? 509 TRP C CD1 1 
ATOM   7703  C CD2 . TRP C 1 307 ? -36.271 15.847  42.778 1.00 25.92  ? 509 TRP C CD2 1 
ATOM   7704  N NE1 . TRP C 1 307 ? -34.156 15.225  42.395 1.00 26.60  ? 509 TRP C NE1 1 
ATOM   7705  C CE2 . TRP C 1 307 ? -34.925 16.143  43.059 1.00 26.52  ? 509 TRP C CE2 1 
ATOM   7706  C CE3 . TRP C 1 307 ? -37.266 16.650  43.337 1.00 26.36  ? 509 TRP C CE3 1 
ATOM   7707  C CZ2 . TRP C 1 307 ? -34.549 17.203  43.876 1.00 27.04  ? 509 TRP C CZ2 1 
ATOM   7708  C CZ3 . TRP C 1 307 ? -36.892 17.696  44.153 1.00 27.12  ? 509 TRP C CZ3 1 
ATOM   7709  C CH2 . TRP C 1 307 ? -35.546 17.965  44.414 1.00 27.69  ? 509 TRP C CH2 1 
ATOM   7710  N N   . ALA C 1 308 ? -39.905 15.873  40.530 1.00 29.24  ? 510 ALA C N   1 
ATOM   7711  C CA  . ALA C 1 308 ? -40.721 17.071  40.626 1.00 29.59  ? 510 ALA C CA  1 
ATOM   7712  C C   . ALA C 1 308 ? -40.967 17.416  42.085 1.00 30.57  ? 510 ALA C C   1 
ATOM   7713  O O   . ALA C 1 308 ? -41.210 16.530  42.909 1.00 31.80  ? 510 ALA C O   1 
ATOM   7714  C CB  . ALA C 1 308 ? -42.056 16.881  39.900 1.00 31.04  ? 510 ALA C CB  1 
ATOM   7715  N N   . LEU C 1 309 ? -40.885 18.704  42.404 1.00 34.96  ? 511 LEU C N   1 
ATOM   7716  C CA  . LEU C 1 309 ? -41.217 19.195  43.735 1.00 35.54  ? 511 LEU C CA  1 
ATOM   7717  C C   . LEU C 1 309 ? -41.942 20.522  43.592 1.00 36.71  ? 511 LEU C C   1 
ATOM   7718  O O   . LEU C 1 309 ? -41.413 21.448  42.970 1.00 36.52  ? 511 LEU C O   1 
ATOM   7719  C CB  . LEU C 1 309 ? -39.957 19.358  44.585 1.00 33.80  ? 511 LEU C CB  1 
ATOM   7720  C CG  . LEU C 1 309 ? -40.137 19.873  46.007 1.00 33.86  ? 511 LEU C CG  1 
ATOM   7721  C CD1 . LEU C 1 309 ? -40.916 18.864  46.819 1.00 34.03  ? 511 LEU C CD1 1 
ATOM   7722  C CD2 . LEU C 1 309 ? -38.790 20.158  46.632 1.00 33.72  ? 511 LEU C CD2 1 
ATOM   7723  N N   . ASN C 1 310 ? -43.132 20.620  44.187 1.00 36.71  ? 512 ASN C N   1 
ATOM   7724  C CA  . ASN C 1 310 ? -43.935 21.846  44.165 1.00 38.54  ? 512 ASN C CA  1 
ATOM   7725  C C   . ASN C 1 310 ? -44.032 22.426  42.755 1.00 39.19  ? 512 ASN C C   1 
ATOM   7726  O O   . ASN C 1 310 ? -43.845 23.624  42.534 1.00 39.70  ? 512 ASN C O   1 
ATOM   7727  C CB  . ASN C 1 310 ? -43.380 22.881  45.144 1.00 43.20  ? 512 ASN C CB  1 
ATOM   7728  C CG  . ASN C 1 310 ? -44.336 24.033  45.378 1.00 45.47  ? 512 ASN C CG  1 
ATOM   7729  O OD1 . ASN C 1 310 ? -45.553 23.863  45.327 1.00 47.42  ? 512 ASN C OD1 1 
ATOM   7730  N ND2 . ASN C 1 310 ? -43.788 25.217  45.621 1.00 44.80  ? 512 ASN C ND2 1 
ATOM   7731  N N   . GLY C 1 311 ? -44.310 21.561  41.783 1.00 37.12  ? 513 GLY C N   1 
ATOM   7732  C CA  . GLY C 1 311 ? -44.462 21.981  40.410 1.00 37.10  ? 513 GLY C CA  1 
ATOM   7733  C C   . GLY C 1 311 ? -43.184 22.381  39.710 1.00 37.94  ? 513 GLY C C   1 
ATOM   7734  O O   . GLY C 1 311 ? -43.252 23.032  38.661 1.00 39.24  ? 513 GLY C O   1 
ATOM   7735  N N   . ARG C 1 312 ? -42.025 22.021  40.250 1.00 36.25  ? 514 ARG C N   1 
ATOM   7736  C CA  . ARG C 1 312 ? -40.742 22.301  39.625 1.00 36.64  ? 514 ARG C CA  1 
ATOM   7737  C C   . ARG C 1 312 ? -39.951 21.014  39.440 1.00 36.39  ? 514 ARG C C   1 
ATOM   7738  O O   . ARG C 1 312 ? -39.728 20.259  40.389 1.00 36.91  ? 514 ARG C O   1 
ATOM   7739  C CB  . ARG C 1 312 ? -39.919 23.293  40.453 1.00 36.68  ? 514 ARG C CB  1 
ATOM   7740  C CG  . ARG C 1 312 ? -40.494 24.689  40.487 1.00 40.68  ? 514 ARG C CG  1 
ATOM   7741  C CD  . ARG C 1 312 ? -39.688 25.603  41.396 1.00 44.73  ? 514 ARG C CD  1 
ATOM   7742  N NE  . ARG C 1 312 ? -39.727 25.175  42.789 1.00 48.92  ? 514 ARG C NE  1 
ATOM   7743  C CZ  . ARG C 1 312 ? -39.128 25.824  43.780 1.00 51.34  ? 514 ARG C CZ  1 
ATOM   7744  N NH1 . ARG C 1 312 ? -38.451 26.933  43.532 1.00 51.98  ? 514 ARG C NH1 1 
ATOM   7745  N NH2 . ARG C 1 312 ? -39.212 25.369  45.021 1.00 52.35  ? 514 ARG C NH2 1 
ATOM   7746  N N   . ASN C 1 313 ? -39.527 20.777  38.204 1.00 35.51  ? 515 ASN C N   1 
ATOM   7747  C CA  . ASN C 1 313 ? -38.706 19.628  37.857 1.00 34.72  ? 515 ASN C CA  1 
ATOM   7748  C C   . ASN C 1 313 ? -37.251 19.912  38.193 1.00 33.31  ? 515 ASN C C   1 
ATOM   7749  O O   . ASN C 1 313 ? -36.672 20.882  37.696 1.00 33.51  ? 515 ASN C O   1 
ATOM   7750  C CB  . ASN C 1 313 ? -38.838 19.292  36.373 1.00 32.62  ? 515 ASN C CB  1 
ATOM   7751  C CG  . ASN C 1 313 ? -40.171 18.678  36.036 1.00 34.23  ? 515 ASN C CG  1 
ATOM   7752  O OD1 . ASN C 1 313 ? -40.404 17.499  36.296 1.00 35.09  ? 515 ASN C OD1 1 
ATOM   7753  N ND2 . ASN C 1 313 ? -41.057 19.470  35.450 1.00 36.09  ? 515 ASN C ND2 1 
ATOM   7754  N N   . SER C 1 314 ? -36.668 19.067  39.035 1.00 29.57  ? 516 SER C N   1 
ATOM   7755  C CA  . SER C 1 314 ? -35.242 19.101  39.321 1.00 28.60  ? 516 SER C CA  1 
ATOM   7756  C C   . SER C 1 314 ? -34.599 17.850  38.748 1.00 28.26  ? 516 SER C C   1 
ATOM   7757  O O   . SER C 1 314 ? -35.143 16.752  38.881 1.00 27.92  ? 516 SER C O   1 
ATOM   7758  C CB  . SER C 1 314 ? -34.974 19.194  40.822 1.00 31.18  ? 516 SER C CB  1 
ATOM   7759  O OG  . SER C 1 314 ? -35.430 20.425  41.349 1.00 32.56  ? 516 SER C OG  1 
ATOM   7760  N N   . LEU C 1 315 ? -33.419 17.989  38.167 1.00 26.87  ? 517 LEU C N   1 
ATOM   7761  C CA  . LEU C 1 315 ? -32.712 16.848  37.610 1.00 27.18  ? 517 LEU C CA  1 
ATOM   7762  C C   . LEU C 1 315 ? -32.301 15.891  38.711 1.00 27.61  ? 517 LEU C C   1 
ATOM   7763  O O   . LEU C 1 315 ? -31.955 16.313  39.805 1.00 28.46  ? 517 LEU C O   1 
ATOM   7764  C CB  . LEU C 1 315 ? -31.462 17.319  36.883 1.00 26.29  ? 517 LEU C CB  1 
ATOM   7765  C CG  . LEU C 1 315 ? -30.941 16.370  35.819 1.00 27.06  ? 517 LEU C CG  1 
ATOM   7766  C CD1 . LEU C 1 315 ? -31.835 16.454  34.596 1.00 26.87  ? 517 LEU C CD1 1 
ATOM   7767  C CD2 . LEU C 1 315 ? -29.511 16.725  35.461 1.00 28.91  ? 517 LEU C CD2 1 
ATOM   7768  N N   . MET C 1 316 ? -32.323 14.596  38.419 1.00 27.86  ? 518 MET C N   1 
ATOM   7769  C CA  . MET C 1 316 ? -31.928 13.580  39.382 1.00 27.77  ? 518 MET C CA  1 
ATOM   7770  C C   . MET C 1 316 ? -30.423 13.445  39.273 1.00 27.57  ? 518 MET C C   1 
ATOM   7771  O O   . MET C 1 316 ? -29.918 12.552  38.610 1.00 27.39  ? 518 MET C O   1 
ATOM   7772  C CB  . MET C 1 316 ? -32.606 12.253  39.053 1.00 27.51  ? 518 MET C CB  1 
ATOM   7773  C CG  . MET C 1 316 ? -32.250 11.100  39.972 1.00 28.87  ? 518 MET C CG  1 
ATOM   7774  S SD  . MET C 1 316 ? -32.904 11.247  41.641 1.00 31.56  ? 518 MET C SD  1 
ATOM   7775  C CE  . MET C 1 316 ? -34.659 11.049  41.365 1.00 29.32  ? 518 MET C CE  1 
ATOM   7776  N N   . ASN C 1 317 ? -29.717 14.357  39.926 1.00 27.68  ? 519 ASN C N   1 
ATOM   7777  C CA  . ASN C 1 317 ? -28.271 14.414  39.897 1.00 27.09  ? 519 ASN C CA  1 
ATOM   7778  C C   . ASN C 1 317 ? -27.728 14.345  41.317 1.00 26.87  ? 519 ASN C C   1 
ATOM   7779  O O   . ASN C 1 317 ? -28.151 15.112  42.167 1.00 27.65  ? 519 ASN C O   1 
ATOM   7780  C CB  . ASN C 1 317 ? -27.870 15.736  39.248 1.00 25.07  ? 519 ASN C CB  1 
ATOM   7781  C CG  . ASN C 1 317 ? -26.384 15.879  39.073 1.00 25.51  ? 519 ASN C CG  1 
ATOM   7782  O OD1 . ASN C 1 317 ? -25.649 14.900  39.117 1.00 27.86  ? 519 ASN C OD1 1 
ATOM   7783  N ND2 . ASN C 1 317 ? -25.930 17.106  38.862 1.00 24.25  ? 519 ASN C ND2 1 
ATOM   7784  N N   . PRO C 1 318 ? -26.764 13.452  41.582 1.00 25.63  ? 520 PRO C N   1 
ATOM   7785  C CA  . PRO C 1 318 ? -26.407 12.171  40.969 1.00 25.44  ? 520 PRO C CA  1 
ATOM   7786  C C   . PRO C 1 318 ? -27.522 11.150  41.134 1.00 25.98  ? 520 PRO C C   1 
ATOM   7787  O O   . PRO C 1 318 ? -27.725 10.319  40.257 1.00 25.74  ? 520 PRO C O   1 
ATOM   7788  C CB  . PRO C 1 318 ? -25.162 11.749  41.738 1.00 24.43  ? 520 PRO C CB  1 
ATOM   7789  C CG  . PRO C 1 318 ? -25.288 12.419  43.050 1.00 24.44  ? 520 PRO C CG  1 
ATOM   7790  C CD  . PRO C 1 318 ? -25.924 13.737  42.755 1.00 25.26  ? 520 PRO C CD  1 
ATOM   7791  N N   . GLY C 1 319 ? -28.216 11.190  42.264 1.00 25.18  ? 521 GLY C N   1 
ATOM   7792  C CA  . GLY C 1 319 ? -29.293 10.254  42.511 1.00 26.20  ? 521 GLY C CA  1 
ATOM   7793  C C   . GLY C 1 319 ? -28.845 9.005   43.231 1.00 27.02  ? 521 GLY C C   1 
ATOM   7794  O O   . GLY C 1 319 ? -27.780 8.987   43.836 1.00 27.51  ? 521 GLY C O   1 
ATOM   7795  N N   . PRO C 1 320 ? -29.662 7.947   43.169 1.00 24.87  ? 522 PRO C N   1 
ATOM   7796  C CA  . PRO C 1 320 ? -29.366 6.675   43.835 1.00 24.60  ? 522 PRO C CA  1 
ATOM   7797  C C   . PRO C 1 320 ? -28.085 6.058   43.307 1.00 24.31  ? 522 PRO C C   1 
ATOM   7798  O O   . PRO C 1 320 ? -27.790 6.176   42.123 1.00 25.39  ? 522 PRO C O   1 
ATOM   7799  C CB  . PRO C 1 320 ? -30.553 5.789   43.447 1.00 23.51  ? 522 PRO C CB  1 
ATOM   7800  C CG  . PRO C 1 320 ? -31.630 6.730   43.046 1.00 24.83  ? 522 PRO C CG  1 
ATOM   7801  C CD  . PRO C 1 320 ? -30.935 7.905   42.435 1.00 24.25  ? 522 PRO C CD  1 
ATOM   7802  N N   . ALA C 1 321 ? -27.318 5.429   44.187 1.00 19.16  ? 523 ALA C N   1 
ATOM   7803  C CA  . ALA C 1 321 ? -26.065 4.805   43.798 1.00 18.96  ? 523 ALA C CA  1 
ATOM   7804  C C   . ALA C 1 321 ? -26.316 3.603   42.923 1.00 19.07  ? 523 ALA C C   1 
ATOM   7805  O O   . ALA C 1 321 ? -26.978 2.665   43.332 1.00 18.76  ? 523 ALA C O   1 
ATOM   7806  C CB  . ALA C 1 321 ? -25.280 4.396   45.028 1.00 20.81  ? 523 ALA C CB  1 
ATOM   7807  N N   . MET C 1 322 ? -25.797 3.644   41.707 1.00 15.77  ? 524 MET C N   1 
ATOM   7808  C CA  . MET C 1 322 ? -25.940 2.560   40.750 1.00 16.60  ? 524 MET C CA  1 
ATOM   7809  C C   . MET C 1 322 ? -24.659 2.446   39.944 1.00 17.02  ? 524 MET C C   1 
ATOM   7810  O O   . MET C 1 322 ? -23.907 3.414   39.813 1.00 18.61  ? 524 MET C O   1 
ATOM   7811  C CB  . MET C 1 322 ? -27.119 2.787   39.805 1.00 14.64  ? 524 MET C CB  1 
ATOM   7812  C CG  . MET C 1 322 ? -28.478 2.738   40.454 1.00 17.34  ? 524 MET C CG  1 
ATOM   7813  S SD  . MET C 1 322 ? -29.741 3.053   39.222 1.00 20.93  ? 524 MET C SD  1 
ATOM   7814  C CE  . MET C 1 322 ? -29.479 4.801   38.980 1.00 23.01  ? 524 MET C CE  1 
ATOM   7815  N N   . ALA C 1 323 ? -24.414 1.254   39.409 1.00 14.39  ? 525 ALA C N   1 
ATOM   7816  C CA  . ALA C 1 323 ? -23.234 1.041   38.585 1.00 15.39  ? 525 ALA C CA  1 
ATOM   7817  C C   . ALA C 1 323 ? -23.296 1.916   37.342 1.00 16.76  ? 525 ALA C C   1 
ATOM   7818  O O   . ALA C 1 323 ? -24.333 1.998   36.678 1.00 17.22  ? 525 ALA C O   1 
ATOM   7819  C CB  . ALA C 1 323 ? -23.115 -0.427  38.195 1.00 17.57  ? 525 ALA C CB  1 
ATOM   7820  N N   . SER C 1 324 ? -22.197 2.588   37.024 1.00 15.76  ? 526 SER C N   1 
ATOM   7821  C CA  . SER C 1 324 ? -22.158 3.463   35.858 1.00 17.55  ? 526 SER C CA  1 
ATOM   7822  C C   . SER C 1 324 ? -22.380 2.705   34.560 1.00 18.72  ? 526 SER C C   1 
ATOM   7823  O O   . SER C 1 324 ? -23.173 3.117   33.725 1.00 18.87  ? 526 SER C O   1 
ATOM   7824  C CB  . SER C 1 324 ? -20.833 4.213   35.791 1.00 16.59  ? 526 SER C CB  1 
ATOM   7825  O OG  . SER C 1 324 ? -20.598 4.928   36.984 1.00 19.32  ? 526 SER C OG  1 
ATOM   7826  N N   . HIS C 1 325 ? -21.665 1.603   34.391 1.00 17.47  ? 527 HIS C N   1 
ATOM   7827  C CA  . HIS C 1 325 ? -21.777 0.792   33.193 1.00 19.95  ? 527 HIS C CA  1 
ATOM   7828  C C   . HIS C 1 325 ? -21.558 -0.667  33.523 1.00 21.49  ? 527 HIS C C   1 
ATOM   7829  O O   . HIS C 1 325 ? -21.070 -0.998  34.595 1.00 21.51  ? 527 HIS C O   1 
ATOM   7830  C CB  . HIS C 1 325 ? -20.747 1.223   32.163 1.00 21.22  ? 527 HIS C CB  1 
ATOM   7831  C CG  . HIS C 1 325 ? -19.361 1.322   32.712 1.00 22.04  ? 527 HIS C CG  1 
ATOM   7832  N ND1 . HIS C 1 325 ? -18.705 0.250   33.274 1.00 22.60  ? 527 HIS C ND1 1 
ATOM   7833  C CD2 . HIS C 1 325 ? -18.508 2.368   32.791 1.00 22.07  ? 527 HIS C CD2 1 
ATOM   7834  C CE1 . HIS C 1 325 ? -17.510 0.632   33.683 1.00 21.66  ? 527 HIS C CE1 1 
ATOM   7835  N NE2 . HIS C 1 325 ? -17.364 1.912   33.396 1.00 21.60  ? 527 HIS C NE2 1 
ATOM   7836  N N   . LYS C 1 326 ? -21.953 -1.538  32.602 1.00 22.31  ? 528 LYS C N   1 
ATOM   7837  C CA  . LYS C 1 326 ? -21.765 -2.975  32.745 1.00 25.07  ? 528 LYS C CA  1 
ATOM   7838  C C   . LYS C 1 326 ? -20.290 -3.316  32.577 1.00 27.07  ? 528 LYS C C   1 
ATOM   7839  O O   . LYS C 1 326 ? -19.558 -2.595  31.913 1.00 26.59  ? 528 LYS C O   1 
ATOM   7840  C CB  . LYS C 1 326 ? -22.590 -3.726  31.702 1.00 22.61  ? 528 LYS C CB  1 
ATOM   7841  C CG  . LYS C 1 326 ? -24.081 -3.704  31.961 1.00 23.21  ? 528 LYS C CG  1 
ATOM   7842  C CD  . LYS C 1 326 ? -24.850 -4.429  30.875 1.00 25.39  ? 528 LYS C CD  1 
ATOM   7843  C CE  . LYS C 1 326 ? -24.818 -3.655  29.573 1.00 25.79  ? 528 LYS C CE  1 
ATOM   7844  N NZ  . LYS C 1 326 ? -25.826 -4.164  28.606 1.00 26.19  ? 528 LYS C NZ  1 
ATOM   7845  N N   . GLU C 1 327 ? -19.848 -4.430  33.146 1.00 25.61  ? 529 GLU C N   1 
ATOM   7846  C CA  . GLU C 1 327 ? -18.447 -4.807  33.031 1.00 29.33  ? 529 GLU C CA  1 
ATOM   7847  C C   . GLU C 1 327 ? -18.084 -5.001  31.570 1.00 30.04  ? 529 GLU C C   1 
ATOM   7848  O O   . GLU C 1 327 ? -18.846 -5.577  30.802 1.00 30.08  ? 529 GLU C O   1 
ATOM   7849  C CB  . GLU C 1 327 ? -18.173 -6.098  33.795 1.00 32.20  ? 529 GLU C CB  1 
ATOM   7850  C CG  . GLU C 1 327 ? -16.699 -6.454  33.922 1.00 37.98  ? 529 GLU C CG  1 
ATOM   7851  C CD  . GLU C 1 327 ? -16.042 -5.801  35.122 1.00 40.99  ? 529 GLU C CD  1 
ATOM   7852  O OE1 . GLU C 1 327 ? -16.744 -5.555  36.123 1.00 41.38  ? 529 GLU C OE1 1 
ATOM   7853  O OE2 . GLU C 1 327 ? -14.822 -5.539  35.071 1.00 42.94  ? 529 GLU C OE2 1 
ATOM   7854  N N   . GLY C 1 328 ? -16.896 -4.544  31.196 1.00 30.25  ? 530 GLY C N   1 
ATOM   7855  C CA  . GLY C 1 328 ? -16.442 -4.646  29.824 1.00 30.98  ? 530 GLY C CA  1 
ATOM   7856  C C   . GLY C 1 328 ? -16.851 -3.482  28.944 1.00 31.47  ? 530 GLY C C   1 
ATOM   7857  O O   . GLY C 1 328 ? -16.661 -3.524  27.735 1.00 32.43  ? 530 GLY C O   1 
ATOM   7858  N N   . GLU C 1 329 ? -17.439 -2.453  29.546 1.00 26.07  ? 531 GLU C N   1 
ATOM   7859  C CA  . GLU C 1 329 ? -17.847 -1.260  28.812 1.00 25.59  ? 531 GLU C CA  1 
ATOM   7860  C C   . GLU C 1 329 ? -17.045 -0.097  29.359 1.00 23.89  ? 531 GLU C C   1 
ATOM   7861  O O   . GLU C 1 329 ? -16.974 0.084   30.560 1.00 23.87  ? 531 GLU C O   1 
ATOM   7862  C CB  . GLU C 1 329 ? -19.335 -0.982  29.005 1.00 22.26  ? 531 GLU C CB  1 
ATOM   7863  C CG  . GLU C 1 329 ? -20.250 -2.076  28.494 1.00 26.31  ? 531 GLU C CG  1 
ATOM   7864  C CD  . GLU C 1 329 ? -21.716 -1.712  28.610 1.00 29.85  ? 531 GLU C CD  1 
ATOM   7865  O OE1 . GLU C 1 329 ? -22.088 -1.027  29.586 1.00 32.02  ? 531 GLU C OE1 1 
ATOM   7866  O OE2 . GLU C 1 329 ? -22.500 -2.111  27.725 1.00 30.84  ? 531 GLU C OE2 1 
ATOM   7867  N N   . ASP C 1 330 ? -16.393 0.660   28.490 1.00 20.46  ? 532 ASP C N   1 
ATOM   7868  C CA  . ASP C 1 330 ? -15.610 1.796   28.946 1.00 18.81  ? 532 ASP C CA  1 
ATOM   7869  C C   . ASP C 1 330 ? -16.012 3.087   28.264 1.00 15.62  ? 532 ASP C C   1 
ATOM   7870  O O   . ASP C 1 330 ? -15.547 4.159   28.622 1.00 14.60  ? 532 ASP C O   1 
ATOM   7871  C CB  . ASP C 1 330 ? -14.140 1.522   28.676 1.00 14.09  ? 532 ASP C CB  1 
ATOM   7872  C CG  . ASP C 1 330 ? -13.910 0.963   27.299 1.00 19.19  ? 532 ASP C CG  1 
ATOM   7873  O OD1 . ASP C 1 330 ? -14.846 1.031   26.485 1.00 21.69  ? 532 ASP C OD1 1 
ATOM   7874  O OD2 . ASP C 1 330 ? -12.808 0.454   27.025 1.00 22.33  ? 532 ASP C OD2 1 
ATOM   7875  N N   . ARG C 1 331 ? -16.906 2.977   27.296 1.00 18.15  ? 533 ARG C N   1 
ATOM   7876  C CA  . ARG C 1 331 ? -17.319 4.111   26.488 1.00 14.53  ? 533 ARG C CA  1 
ATOM   7877  C C   . ARG C 1 331 ? -18.677 4.707   26.824 1.00 13.18  ? 533 ARG C C   1 
ATOM   7878  O O   . ARG C 1 331 ? -19.134 5.620   26.162 1.00 12.40  ? 533 ARG C O   1 
ATOM   7879  C CB  . ARG C 1 331 ? -17.303 3.656   25.036 1.00 15.49  ? 533 ARG C CB  1 
ATOM   7880  C CG  . ARG C 1 331 ? -17.808 4.648   24.026 1.00 13.32  ? 533 ARG C CG  1 
ATOM   7881  C CD  . ARG C 1 331 ? -18.106 3.944   22.723 1.00 13.47  ? 533 ARG C CD  1 
ATOM   7882  N NE  . ARG C 1 331 ? -18.421 2.538   22.925 1.00 13.98  ? 533 ARG C NE  1 
ATOM   7883  C CZ  . ARG C 1 331 ? -19.055 1.789   22.037 1.00 14.10  ? 533 ARG C CZ  1 
ATOM   7884  N NH1 . ARG C 1 331 ? -19.453 2.318   20.896 1.00 14.60  ? 533 ARG C NH1 1 
ATOM   7885  N NH2 . ARG C 1 331 ? -19.301 0.519   22.292 1.00 12.39  ? 533 ARG C NH2 1 
ATOM   7886  N N   . PHE C 1 332 ? -19.322 4.226   27.871 1.00 16.80  ? 534 PHE C N   1 
ATOM   7887  C CA  . PHE C 1 332 ? -20.640 4.751   28.189 1.00 14.32  ? 534 PHE C CA  1 
ATOM   7888  C C   . PHE C 1 332 ? -20.723 5.215   29.637 1.00 13.34  ? 534 PHE C C   1 
ATOM   7889  O O   . PHE C 1 332 ? -20.153 4.600   30.540 1.00 14.34  ? 534 PHE C O   1 
ATOM   7890  C CB  . PHE C 1 332 ? -21.717 3.701   27.929 1.00 13.40  ? 534 PHE C CB  1 
ATOM   7891  C CG  . PHE C 1 332 ? -21.747 3.203   26.519 1.00 13.62  ? 534 PHE C CG  1 
ATOM   7892  C CD1 . PHE C 1 332 ? -22.251 3.989   25.502 1.00 14.08  ? 534 PHE C CD1 1 
ATOM   7893  C CD2 . PHE C 1 332 ? -21.314 1.927   26.217 1.00 14.25  ? 534 PHE C CD2 1 
ATOM   7894  C CE1 . PHE C 1 332 ? -22.282 3.526   24.206 1.00 14.26  ? 534 PHE C CE1 1 
ATOM   7895  C CE2 . PHE C 1 332 ? -21.356 1.457   24.922 1.00 14.08  ? 534 PHE C CE2 1 
ATOM   7896  C CZ  . PHE C 1 332 ? -21.848 2.255   23.919 1.00 13.99  ? 534 PHE C CZ  1 
ATOM   7897  N N   . PHE C 1 333 ? -21.499 6.274   29.844 1.00 15.61  ? 535 PHE C N   1 
ATOM   7898  C CA  . PHE C 1 333 ? -21.732 6.846   31.162 1.00 13.73  ? 535 PHE C CA  1 
ATOM   7899  C C   . PHE C 1 333 ? -23.157 7.383   31.254 1.00 12.75  ? 535 PHE C C   1 
ATOM   7900  O O   . PHE C 1 333 ? -23.722 7.813   30.263 1.00 12.26  ? 535 PHE C O   1 
ATOM   7901  C CB  . PHE C 1 333 ? -20.713 7.950   31.480 1.00 14.06  ? 535 PHE C CB  1 
ATOM   7902  C CG  . PHE C 1 333 ? -20.721 9.093   30.508 1.00 14.31  ? 535 PHE C CG  1 
ATOM   7903  C CD1 . PHE C 1 333 ? -21.459 10.230  30.765 1.00 13.35  ? 535 PHE C CD1 1 
ATOM   7904  C CD2 . PHE C 1 333 ? -19.980 9.037   29.350 1.00 14.56  ? 535 PHE C CD2 1 
ATOM   7905  C CE1 . PHE C 1 333 ? -21.465 11.285  29.878 1.00 12.22  ? 535 PHE C CE1 1 
ATOM   7906  C CE2 . PHE C 1 333 ? -19.984 10.086  28.459 1.00 13.49  ? 535 PHE C CE2 1 
ATOM   7907  C CZ  . PHE C 1 333 ? -20.725 11.213  28.723 1.00 12.38  ? 535 PHE C CZ  1 
ATOM   7908  N N   . PRO C 1 334 ? -23.750 7.341   32.447 1.00 16.30  ? 536 PRO C N   1 
ATOM   7909  C CA  . PRO C 1 334 ? -25.106 7.835   32.679 1.00 15.90  ? 536 PRO C CA  1 
ATOM   7910  C C   . PRO C 1 334 ? -25.151 9.345   32.483 1.00 15.67  ? 536 PRO C C   1 
ATOM   7911  O O   . PRO C 1 334 ? -24.203 10.026  32.842 1.00 15.46  ? 536 PRO C O   1 
ATOM   7912  C CB  . PRO C 1 334 ? -25.363 7.472   34.138 1.00 16.33  ? 536 PRO C CB  1 
ATOM   7913  C CG  . PRO C 1 334 ? -24.016 7.345   34.742 1.00 16.40  ? 536 PRO C CG  1 
ATOM   7914  C CD  . PRO C 1 334 ? -23.143 6.796   33.666 1.00 16.32  ? 536 PRO C CD  1 
ATOM   7915  N N   . LEU C 1 335 ? -26.253 9.869   31.966 1.00 18.39  ? 537 LEU C N   1 
ATOM   7916  C CA  . LEU C 1 335 ? -26.343 11.294  31.686 1.00 18.79  ? 537 LEU C CA  1 
ATOM   7917  C C   . LEU C 1 335 ? -26.177 12.188  32.914 1.00 19.75  ? 537 LEU C C   1 
ATOM   7918  O O   . LEU C 1 335 ? -25.489 13.201  32.849 1.00 20.04  ? 537 LEU C O   1 
ATOM   7919  C CB  . LEU C 1 335 ? -27.675 11.591  31.003 1.00 20.79  ? 537 LEU C CB  1 
ATOM   7920  C CG  . LEU C 1 335 ? -27.770 12.899  30.234 1.00 20.69  ? 537 LEU C CG  1 
ATOM   7921  C CD1 . LEU C 1 335 ? -29.160 13.044  29.650 1.00 20.75  ? 537 LEU C CD1 1 
ATOM   7922  C CD2 . LEU C 1 335 ? -27.443 14.061  31.149 1.00 21.60  ? 537 LEU C CD2 1 
ATOM   7923  N N   . SER C 1 336 ? -26.827 11.844  34.017 1.00 18.46  ? 538 SER C N   1 
ATOM   7924  C CA  . SER C 1 336 ? -26.674 12.604  35.256 1.00 19.88  ? 538 SER C CA  1 
ATOM   7925  C C   . SER C 1 336 ? -26.240 11.691  36.394 1.00 20.11  ? 538 SER C C   1 
ATOM   7926  O O   . SER C 1 336 ? -26.290 12.064  37.552 1.00 20.49  ? 538 SER C O   1 
ATOM   7927  C CB  . SER C 1 336 ? -27.952 13.363  35.611 1.00 25.59  ? 538 SER C CB  1 
ATOM   7928  O OG  . SER C 1 336 ? -29.106 12.663  35.192 1.00 28.52  ? 538 SER C OG  1 
ATOM   7929  N N   . GLY C 1 337 ? -25.814 10.491  36.043 1.00 19.41  ? 539 GLY C N   1 
ATOM   7930  C CA  . GLY C 1 337 ? -25.418 9.469   36.992 1.00 20.55  ? 539 GLY C CA  1 
ATOM   7931  C C   . GLY C 1 337 ? -24.245 9.640   37.927 1.00 21.14  ? 539 GLY C C   1 
ATOM   7932  O O   . GLY C 1 337 ? -24.295 9.188   39.059 1.00 23.50  ? 539 GLY C O   1 
ATOM   7933  N N   . SER C 1 338 ? -23.174 10.260  37.459 1.00 22.80  ? 540 SER C N   1 
ATOM   7934  C CA  . SER C 1 338 ? -21.980 10.405  38.278 1.00 22.83  ? 540 SER C CA  1 
ATOM   7935  C C   . SER C 1 338 ? -21.545 11.841  38.441 1.00 21.60  ? 540 SER C C   1 
ATOM   7936  O O   . SER C 1 338 ? -21.903 12.696  37.648 1.00 21.58  ? 540 SER C O   1 
ATOM   7937  C CB  . SER C 1 338 ? -20.826 9.622   37.653 1.00 19.76  ? 540 SER C CB  1 
ATOM   7938  O OG  . SER C 1 338 ? -21.274 8.402   37.092 1.00 21.31  ? 540 SER C OG  1 
ATOM   7939  N N   . LEU C 1 339 ? -20.796 12.101  39.504 1.00 19.45  ? 541 LEU C N   1 
ATOM   7940  C CA  . LEU C 1 339 ? -20.269 13.426  39.762 1.00 18.26  ? 541 LEU C CA  1 
ATOM   7941  C C   . LEU C 1 339 ? -19.240 13.751  38.696 1.00 18.04  ? 541 LEU C C   1 
ATOM   7942  O O   . LEU C 1 339 ? -18.491 12.889  38.265 1.00 18.53  ? 541 LEU C O   1 
ATOM   7943  C CB  . LEU C 1 339 ? -19.601 13.484  41.133 1.00 21.56  ? 541 LEU C CB  1 
ATOM   7944  C CG  . LEU C 1 339 ? -20.404 13.029  42.347 1.00 20.64  ? 541 LEU C CG  1 
ATOM   7945  C CD1 . LEU C 1 339 ? -19.527 13.067  43.583 1.00 20.17  ? 541 LEU C CD1 1 
ATOM   7946  C CD2 . LEU C 1 339 ? -21.628 13.903  42.540 1.00 20.02  ? 541 LEU C CD2 1 
ATOM   7947  N N   . ILE C 1 340 ? -19.212 15.005  38.277 1.00 17.16  ? 542 ILE C N   1 
ATOM   7948  C CA  . ILE C 1 340 ? -18.284 15.495  37.265 1.00 17.55  ? 542 ILE C CA  1 
ATOM   7949  C C   . ILE C 1 340 ? -17.478 16.634  37.872 1.00 17.01  ? 542 ILE C C   1 
ATOM   7950  O O   . ILE C 1 340 ? -18.049 17.622  38.346 1.00 16.01  ? 542 ILE C O   1 
ATOM   7951  C CB  . ILE C 1 340 ? -19.013 15.953  35.994 1.00 12.90  ? 542 ILE C CB  1 
ATOM   7952  C CG1 . ILE C 1 340 ? -19.733 14.775  35.341 1.00 15.74  ? 542 ILE C CG1 1 
ATOM   7953  C CG2 . ILE C 1 340 ? -18.026 16.556  35.016 1.00 14.18  ? 542 ILE C CG2 1 
ATOM   7954  C CD1 . ILE C 1 340 ? -20.658 15.175  34.227 1.00 17.58  ? 542 ILE C CD1 1 
ATOM   7955  N N   . PHE C 1 341 ? -16.159 16.488  37.869 1.00 18.78  ? 543 PHE C N   1 
ATOM   7956  C CA  . PHE C 1 341 ? -15.232 17.510  38.332 1.00 18.65  ? 543 PHE C CA  1 
ATOM   7957  C C   . PHE C 1 341 ? -14.549 18.164  37.140 1.00 18.06  ? 543 PHE C C   1 
ATOM   7958  O O   . PHE C 1 341 ? -14.213 17.507  36.154 1.00 16.89  ? 543 PHE C O   1 
ATOM   7959  C CB  . PHE C 1 341 ? -14.165 16.911  39.254 1.00 14.12  ? 543 PHE C CB  1 
ATOM   7960  C CG  . PHE C 1 341 ? -14.713 16.246  40.475 1.00 14.61  ? 543 PHE C CG  1 
ATOM   7961  C CD1 . PHE C 1 341 ? -15.044 16.984  41.591 1.00 14.69  ? 543 PHE C CD1 1 
ATOM   7962  C CD2 . PHE C 1 341 ? -14.877 14.878  40.512 1.00 14.46  ? 543 PHE C CD2 1 
ATOM   7963  C CE1 . PHE C 1 341 ? -15.545 16.369  42.715 1.00 14.24  ? 543 PHE C CE1 1 
ATOM   7964  C CE2 . PHE C 1 341 ? -15.376 14.258  41.635 1.00 14.14  ? 543 PHE C CE2 1 
ATOM   7965  C CZ  . PHE C 1 341 ? -15.711 15.005  42.737 1.00 14.00  ? 543 PHE C CZ  1 
ATOM   7966  N N   . GLY C 1 342 ? -14.352 19.472  37.234 1.00 17.06  ? 544 GLY C N   1 
ATOM   7967  C CA  . GLY C 1 342 ? -13.565 20.216  36.262 1.00 17.11  ? 544 GLY C CA  1 
ATOM   7968  C C   . GLY C 1 342 ? -12.091 20.170  36.621 1.00 17.31  ? 544 GLY C C   1 
ATOM   7969  O O   . GLY C 1 342 ? -11.729 20.221  37.799 1.00 17.85  ? 544 GLY C O   1 
ATOM   7970  N N   . LYS C 1 343 ? -11.249 20.077  35.598 1.00 18.89  ? 545 LYS C N   1 
ATOM   7971  C CA  . LYS C 1 343 ? -9.819  20.242  35.782 1.00 18.46  ? 545 LYS C CA  1 
ATOM   7972  C C   . LYS C 1 343 ? -9.500  21.718  35.992 1.00 19.06  ? 545 LYS C C   1 
ATOM   7973  O O   . LYS C 1 343 ? -10.321 22.596  35.725 1.00 18.19  ? 545 LYS C O   1 
ATOM   7974  C CB  . LYS C 1 343 ? -9.054  19.680  34.586 1.00 15.20  ? 545 LYS C CB  1 
ATOM   7975  C CG  . LYS C 1 343 ? -9.163  18.169  34.445 1.00 15.70  ? 545 LYS C CG  1 
ATOM   7976  C CD  . LYS C 1 343 ? -8.472  17.673  33.188 1.00 16.75  ? 545 LYS C CD  1 
ATOM   7977  C CE  . LYS C 1 343 ? -8.549  16.163  33.074 1.00 18.66  ? 545 LYS C CE  1 
ATOM   7978  N NZ  . LYS C 1 343 ? -7.965  15.669  31.798 1.00 19.89  ? 545 LYS C NZ  1 
ATOM   7979  N N   . GLN C 1 344 ? -8.312  21.996  36.519 1.00 20.97  ? 546 GLN C N   1 
ATOM   7980  C CA  . GLN C 1 344 ? -7.967  23.387  36.779 1.00 22.15  ? 546 GLN C CA  1 
ATOM   7981  C C   . GLN C 1 344 ? -7.728  24.135  35.475 1.00 22.18  ? 546 GLN C C   1 
ATOM   7982  O O   . GLN C 1 344 ? -7.195  23.579  34.512 1.00 21.62  ? 546 GLN C O   1 
ATOM   7983  C CB  . GLN C 1 344 ? -6.742  23.490  37.677 1.00 20.81  ? 546 GLN C CB  1 
ATOM   7984  C CG  . GLN C 1 344 ? -6.490  24.919  38.110 1.00 25.21  ? 546 GLN C CG  1 
ATOM   7985  C CD  . GLN C 1 344 ? -5.436  25.022  39.161 1.00 27.31  ? 546 GLN C CD  1 
ATOM   7986  O OE1 . GLN C 1 344 ? -4.941  24.013  39.641 1.00 29.67  ? 546 GLN C OE1 1 
ATOM   7987  N NE2 . GLN C 1 344 ? -5.085  26.246  39.536 1.00 27.22  ? 546 GLN C NE2 1 
ATOM   7988  N N   . GLY C 1 345 ? -8.222  25.369  35.419 1.00 22.63  ? 547 GLY C N   1 
ATOM   7989  C CA  . GLY C 1 345 ? -8.115  26.204  34.242 1.00 22.78  ? 547 GLY C CA  1 
ATOM   7990  C C   . GLY C 1 345 ? -9.390  26.127  33.424 1.00 23.15  ? 547 GLY C C   1 
ATOM   7991  O O   . GLY C 1 345 ? -9.638  26.972  32.566 1.00 23.74  ? 547 GLY C O   1 
ATOM   7992  N N   . THR C 1 346 ? -10.202 25.112  33.709 1.00 21.84  ? 548 THR C N   1 
ATOM   7993  C CA  . THR C 1 346 ? -11.450 24.874  33.014 1.00 21.50  ? 548 THR C CA  1 
ATOM   7994  C C   . THR C 1 346 ? -12.440 26.000  33.229 1.00 22.36  ? 548 THR C C   1 
ATOM   7995  O O   . THR C 1 346 ? -12.624 26.484  34.341 1.00 20.83  ? 548 THR C O   1 
ATOM   7996  C CB  . THR C 1 346 ? -12.067 23.553  33.485 1.00 18.39  ? 548 THR C CB  1 
ATOM   7997  O OG1 . THR C 1 346 ? -11.104 22.511  33.320 1.00 19.09  ? 548 THR C OG1 1 
ATOM   7998  C CG2 . THR C 1 346 ? -13.303 23.206  32.691 1.00 17.09  ? 548 THR C CG2 1 
ATOM   7999  N N   . GLY C 1 347 ? -13.086 26.395  32.138 1.00 22.58  ? 549 GLY C N   1 
ATOM   8000  C CA  . GLY C 1 347 ? -14.067 27.457  32.130 1.00 24.02  ? 549 GLY C CA  1 
ATOM   8001  C C   . GLY C 1 347 ? -15.402 27.105  32.745 1.00 25.57  ? 549 GLY C C   1 
ATOM   8002  O O   . GLY C 1 347 ? -15.730 25.943  32.957 1.00 24.28  ? 549 GLY C O   1 
ATOM   8003  N N   . ARG C 1 348 ? -16.136 28.143  33.105 1.00 23.41  ? 550 ARG C N   1 
ATOM   8004  C CA  . ARG C 1 348 ? -17.465 28.025  33.680 1.00 26.30  ? 550 ARG C CA  1 
ATOM   8005  C C   . ARG C 1 348 ? -18.542 27.462  32.740 1.00 26.85  ? 550 ARG C C   1 
ATOM   8006  O O   . ARG C 1 348 ? -19.390 26.695  33.171 1.00 26.40  ? 550 ARG C O   1 
ATOM   8007  C CB  . ARG C 1 348 ? -17.901 29.383  34.230 1.00 24.15  ? 550 ARG C CB  1 
ATOM   8008  C CG  . ARG C 1 348 ? -18.891 29.309  35.373 1.00 32.50  ? 550 ARG C CG  1 
ATOM   8009  C CD  . ARG C 1 348 ? -19.375 30.692  35.771 1.00 37.49  ? 550 ARG C CD  1 
ATOM   8010  N NE  . ARG C 1 348 ? -20.458 30.624  36.746 1.00 42.39  ? 550 ARG C NE  1 
ATOM   8011  C CZ  . ARG C 1 348 ? -21.723 30.364  36.435 1.00 45.75  ? 550 ARG C CZ  1 
ATOM   8012  N NH1 . ARG C 1 348 ? -22.063 30.144  35.175 1.00 45.89  ? 550 ARG C NH1 1 
ATOM   8013  N NH2 . ARG C 1 348 ? -22.649 30.321  37.384 1.00 47.46  ? 550 ARG C NH2 1 
ATOM   8014  N N   . ASP C 1 349 ? -18.525 27.848  31.467 1.00 23.67  ? 551 ASP C N   1 
ATOM   8015  C CA  . ASP C 1 349 ? -19.573 27.399  30.543 1.00 25.05  ? 551 ASP C CA  1 
ATOM   8016  C C   . ASP C 1 349 ? -19.188 26.632  29.278 1.00 23.80  ? 551 ASP C C   1 
ATOM   8017  O O   . ASP C 1 349 ? -18.351 27.066  28.497 1.00 24.02  ? 551 ASP C O   1 
ATOM   8018  C CB  . ASP C 1 349 ? -20.421 28.599  30.107 1.00 33.60  ? 551 ASP C CB  1 
ATOM   8019  C CG  . ASP C 1 349 ? -21.019 29.354  31.275 1.00 38.80  ? 551 ASP C CG  1 
ATOM   8020  O OD1 . ASP C 1 349 ? -21.471 28.706  32.241 1.00 41.62  ? 551 ASP C OD1 1 
ATOM   8021  O OD2 . ASP C 1 349 ? -21.049 30.600  31.221 1.00 40.61  ? 551 ASP C OD2 1 
ATOM   8022  N N   . ASN C 1 350 ? -19.840 25.489  29.095 1.00 23.71  ? 552 ASN C N   1 
ATOM   8023  C CA  . ASN C 1 350 ? -19.702 24.627  27.919 1.00 21.92  ? 552 ASN C CA  1 
ATOM   8024  C C   . ASN C 1 350 ? -18.303 24.187  27.515 1.00 19.91  ? 552 ASN C C   1 
ATOM   8025  O O   . ASN C 1 350 ? -17.984 24.177  26.335 1.00 19.26  ? 552 ASN C O   1 
ATOM   8026  C CB  . ASN C 1 350 ? -20.452 25.218  26.722 1.00 26.54  ? 552 ASN C CB  1 
ATOM   8027  C CG  . ASN C 1 350 ? -21.956 25.083  26.854 1.00 27.85  ? 552 ASN C CG  1 
ATOM   8028  O OD1 . ASN C 1 350 ? -22.456 24.474  27.796 1.00 27.05  ? 552 ASN C OD1 1 
ATOM   8029  N ND2 . ASN C 1 350 ? -22.684 25.649  25.907 1.00 29.51  ? 552 ASN C ND2 1 
ATOM   8030  N N   . VAL C 1 351 ? -17.476 23.810  28.479 1.00 17.72  ? 553 VAL C N   1 
ATOM   8031  C CA  . VAL C 1 351 ? -16.116 23.373  28.180 1.00 16.69  ? 553 VAL C CA  1 
ATOM   8032  C C   . VAL C 1 351 ? -16.083 21.995  27.548 1.00 17.11  ? 553 VAL C C   1 
ATOM   8033  O O   . VAL C 1 351 ? -17.025 21.236  27.672 1.00 16.44  ? 553 VAL C O   1 
ATOM   8034  C CB  . VAL C 1 351 ? -15.224 23.387  29.426 1.00 16.03  ? 553 VAL C CB  1 
ATOM   8035  C CG1 . VAL C 1 351 ? -15.163 24.787  30.007 1.00 18.12  ? 553 VAL C CG1 1 
ATOM   8036  C CG2 . VAL C 1 351 ? -15.726 22.388  30.450 1.00 14.66  ? 553 VAL C CG2 1 
ATOM   8037  N N   . ASP C 1 352 ? -14.991 21.681  26.858 1.00 15.12  ? 554 ASP C N   1 
ATOM   8038  C CA  . ASP C 1 352 ? -14.820 20.383  26.199 1.00 17.37  ? 554 ASP C CA  1 
ATOM   8039  C C   . ASP C 1 352 ? -14.637 19.217  27.168 1.00 16.14  ? 554 ASP C C   1 
ATOM   8040  O O   . ASP C 1 352 ? -14.359 19.404  28.345 1.00 16.56  ? 554 ASP C O   1 
ATOM   8041  C CB  . ASP C 1 352 ? -13.656 20.428  25.222 1.00 18.38  ? 554 ASP C CB  1 
ATOM   8042  C CG  . ASP C 1 352 ? -13.523 21.768  24.553 1.00 24.19  ? 554 ASP C CG  1 
ATOM   8043  O OD1 . ASP C 1 352 ? -13.809 21.858  23.344 1.00 26.74  ? 554 ASP C OD1 1 
ATOM   8044  O OD2 . ASP C 1 352 ? -13.146 22.738  25.240 1.00 28.14  ? 554 ASP C OD2 1 
ATOM   8045  N N   . ALA C 1 353 ? -14.752 18.005  26.647 1.00 14.08  ? 555 ALA C N   1 
ATOM   8046  C CA  . ALA C 1 353 ? -14.680 16.812  27.467 1.00 13.10  ? 555 ALA C CA  1 
ATOM   8047  C C   . ALA C 1 353 ? -13.366 16.639  28.196 1.00 13.17  ? 555 ALA C C   1 
ATOM   8048  O O   . ALA C 1 353 ? -13.359 16.194  29.326 1.00 12.67  ? 555 ALA C O   1 
ATOM   8049  C CB  . ALA C 1 353 ? -14.974 15.586  26.623 1.00 12.78  ? 555 ALA C CB  1 
ATOM   8050  N N   . ASP C 1 354 ? -12.252 16.985  27.570 1.00 15.71  ? 556 ASP C N   1 
ATOM   8051  C CA  . ASP C 1 354 ? -10.952 16.816  28.222 1.00 16.26  ? 556 ASP C CA  1 
ATOM   8052  C C   . ASP C 1 354 ? -10.793 17.635  29.505 1.00 14.29  ? 556 ASP C C   1 
ATOM   8053  O O   . ASP C 1 354 ? -10.123 17.208  30.437 1.00 13.42  ? 556 ASP C O   1 
ATOM   8054  C CB  . ASP C 1 354 ? -9.782  17.018  27.253 1.00 14.23  ? 556 ASP C CB  1 
ATOM   8055  C CG  . ASP C 1 354 ? -9.746  18.395  26.659 1.00 19.50  ? 556 ASP C CG  1 
ATOM   8056  O OD1 . ASP C 1 354 ? -10.510 19.260  27.111 1.00 22.97  ? 556 ASP C OD1 1 
ATOM   8057  O OD2 . ASP C 1 354 ? -8.941  18.617  25.737 1.00 22.52  ? 556 ASP C OD2 1 
ATOM   8058  N N   . LYS C 1 355 ? -11.371 18.826  29.531 1.00 18.98  ? 557 LYS C N   1 
ATOM   8059  C CA  . LYS C 1 355 ? -11.311 19.694  30.698 1.00 16.88  ? 557 LYS C CA  1 
ATOM   8060  C C   . LYS C 1 355 ? -11.977 19.094  31.938 1.00 14.39  ? 557 LYS C C   1 
ATOM   8061  O O   . LYS C 1 355 ? -11.515 19.301  33.050 1.00 12.76  ? 557 LYS C O   1 
ATOM   8062  C CB  . LYS C 1 355 ? -11.945 21.036  30.371 1.00 12.23  ? 557 LYS C CB  1 
ATOM   8063  C CG  . LYS C 1 355 ? -11.447 21.635  29.073 1.00 15.26  ? 557 LYS C CG  1 
ATOM   8064  C CD  . LYS C 1 355 ? -9.948  21.841  29.111 1.00 18.95  ? 557 LYS C CD  1 
ATOM   8065  C CE  . LYS C 1 355 ? -9.461  22.496  27.835 1.00 23.34  ? 557 LYS C CE  1 
ATOM   8066  N NZ  . LYS C 1 355 ? -10.022 21.805  26.645 1.00 20.48  ? 557 LYS C NZ  1 
ATOM   8067  N N   . VAL C 1 356 ? -13.100 18.412  31.757 1.00 14.78  ? 558 VAL C N   1 
ATOM   8068  C CA  . VAL C 1 356 ? -13.811 17.777  32.872 1.00 13.97  ? 558 VAL C CA  1 
ATOM   8069  C C   . VAL C 1 356 ? -13.333 16.372  33.265 1.00 13.82  ? 558 VAL C C   1 
ATOM   8070  O O   . VAL C 1 356 ? -12.673 15.690  32.495 1.00 13.82  ? 558 VAL C O   1 
ATOM   8071  C CB  . VAL C 1 356 ? -15.327 17.759  32.634 1.00 12.85  ? 558 VAL C CB  1 
ATOM   8072  C CG1 . VAL C 1 356 ? -15.819 19.170  32.389 1.00 16.40  ? 558 VAL C CG1 1 
ATOM   8073  C CG2 . VAL C 1 356 ? -15.670 16.857  31.466 1.00 12.87  ? 558 VAL C CG2 1 
ATOM   8074  N N   . MET C 1 357 ? -13.672 15.956  34.480 1.00 14.69  ? 559 MET C N   1 
ATOM   8075  C CA  . MET C 1 357 ? -13.328 14.630  34.976 1.00 14.96  ? 559 MET C CA  1 
ATOM   8076  C C   . MET C 1 357 ? -14.599 13.934  35.437 1.00 14.80  ? 559 MET C C   1 
ATOM   8077  O O   . MET C 1 357 ? -15.152 14.287  36.462 1.00 14.25  ? 559 MET C O   1 
ATOM   8078  C CB  . MET C 1 357 ? -12.361 14.725  36.146 1.00 13.05  ? 559 MET C CB  1 
ATOM   8079  C CG  . MET C 1 357 ? -11.109 15.523  35.860 1.00 17.28  ? 559 MET C CG  1 
ATOM   8080  S SD  . MET C 1 357 ? -10.016 15.584  37.283 1.00 21.73  ? 559 MET C SD  1 
ATOM   8081  C CE  . MET C 1 357 ? -11.193 15.862  38.594 1.00 21.43  ? 559 MET C CE  1 
ATOM   8082  N N   . ILE C 1 358 ? -15.064 12.954  34.675 1.00 12.86  ? 560 ILE C N   1 
ATOM   8083  C CA  . ILE C 1 358 ? -16.274 12.226  35.028 1.00 12.81  ? 560 ILE C CA  1 
ATOM   8084  C C   . ILE C 1 358 ? -15.956 10.967  35.827 1.00 14.86  ? 560 ILE C C   1 
ATOM   8085  O O   . ILE C 1 358 ? -15.401 10.019  35.296 1.00 14.85  ? 560 ILE C O   1 
ATOM   8086  C CB  . ILE C 1 358 ? -17.069 11.817  33.777 1.00 13.79  ? 560 ILE C CB  1 
ATOM   8087  C CG1 . ILE C 1 358 ? -17.247 13.002  32.835 1.00 12.32  ? 560 ILE C CG1 1 
ATOM   8088  C CG2 . ILE C 1 358 ? -18.421 11.253  34.169 1.00 12.78  ? 560 ILE C CG2 1 
ATOM   8089  C CD1 . ILE C 1 358 ? -18.055 12.675  31.604 1.00 10.48  ? 560 ILE C CD1 1 
ATOM   8090  N N   . THR C 1 359 ? -16.353 10.961  37.094 1.00 13.16  ? 561 THR C N   1 
ATOM   8091  C CA  . THR C 1 359 ? -16.104 9.835   37.985 1.00 16.21  ? 561 THR C CA  1 
ATOM   8092  C C   . THR C 1 359 ? -16.794 8.545   37.562 1.00 19.56  ? 561 THR C C   1 
ATOM   8093  O O   . THR C 1 359 ? -17.812 8.561   36.887 1.00 19.03  ? 561 THR C O   1 
ATOM   8094  C CB  . THR C 1 359 ? -16.491 10.166  39.434 1.00 14.68  ? 561 THR C CB  1 
ATOM   8095  O OG1 . THR C 1 359 ? -17.888 10.455  39.505 1.00 16.20  ? 561 THR C OG1 1 
ATOM   8096  C CG2 . THR C 1 359 ? -15.720 11.364  39.916 1.00 14.12  ? 561 THR C CG2 1 
ATOM   8097  N N   . ASN C 1 360 ? -16.229 7.421   37.973 1.00 15.25  ? 562 ASN C N   1 
ATOM   8098  C CA  . ASN C 1 360 ? -16.775 6.122   37.626 1.00 19.44  ? 562 ASN C CA  1 
ATOM   8099  C C   . ASN C 1 360 ? -17.165 5.357   38.886 1.00 21.06  ? 562 ASN C C   1 
ATOM   8100  O O   . ASN C 1 360 ? -16.364 5.228   39.804 1.00 22.32  ? 562 ASN C O   1 
ATOM   8101  C CB  . ASN C 1 360 ? -15.729 5.347   36.832 1.00 17.60  ? 562 ASN C CB  1 
ATOM   8102  C CG  . ASN C 1 360 ? -16.335 4.290   35.951 1.00 21.78  ? 562 ASN C CG  1 
ATOM   8103  O OD1 . ASN C 1 360 ? -17.483 3.912   36.127 1.00 26.10  ? 562 ASN C OD1 1 
ATOM   8104  N ND2 . ASN C 1 360 ? -15.565 3.806   34.994 1.00 23.90  ? 562 ASN C ND2 1 
ATOM   8105  N N   . GLU C 1 361 ? -18.392 4.852   38.936 1.00 21.86  ? 563 GLU C N   1 
ATOM   8106  C CA  . GLU C 1 361 ? -18.856 4.096   40.095 1.00 23.87  ? 563 GLU C CA  1 
ATOM   8107  C C   . GLU C 1 361 ? -19.145 2.674   39.670 1.00 22.77  ? 563 GLU C C   1 
ATOM   8108  O O   . GLU C 1 361 ? -20.249 2.181   39.842 1.00 24.41  ? 563 GLU C O   1 
ATOM   8109  C CB  . GLU C 1 361 ? -20.123 4.717   40.681 1.00 18.59  ? 563 GLU C CB  1 
ATOM   8110  C CG  . GLU C 1 361 ? -19.961 6.150   41.153 1.00 24.35  ? 563 GLU C CG  1 
ATOM   8111  C CD  . GLU C 1 361 ? -19.269 6.261   42.498 1.00 27.41  ? 563 GLU C CD  1 
ATOM   8112  O OE1 . GLU C 1 361 ? -19.704 5.595   43.458 1.00 27.58  ? 563 GLU C OE1 1 
ATOM   8113  O OE2 . GLU C 1 361 ? -18.294 7.029   42.600 1.00 29.88  ? 563 GLU C OE2 1 
ATOM   8114  N N   . GLU C 1 362 ? -18.131 2.017   39.126 1.00 25.03  ? 564 GLU C N   1 
ATOM   8115  C CA  . GLU C 1 362 ? -18.239 0.657   38.610 1.00 23.60  ? 564 GLU C CA  1 
ATOM   8116  C C   . GLU C 1 362 ? -17.907 -0.377  39.680 1.00 21.51  ? 564 GLU C C   1 
ATOM   8117  O O   . GLU C 1 362 ? -18.113 -1.565  39.496 1.00 21.14  ? 564 GLU C O   1 
ATOM   8118  C CB  . GLU C 1 362 ? -17.350 0.475   37.383 1.00 27.16  ? 564 GLU C CB  1 
ATOM   8119  C CG  . GLU C 1 362 ? -15.869 0.372   37.695 1.00 31.32  ? 564 GLU C CG  1 
ATOM   8120  C CD  . GLU C 1 362 ? -15.458 -1.032  38.082 1.00 33.60  ? 564 GLU C CD  1 
ATOM   8121  O OE1 . GLU C 1 362 ? -16.197 -1.980  37.748 1.00 34.34  ? 564 GLU C OE1 1 
ATOM   8122  O OE2 . GLU C 1 362 ? -14.398 -1.190  38.719 1.00 34.76  ? 564 GLU C OE2 1 
ATOM   8123  N N   . GLU C 1 363 ? -17.378 0.092   40.798 1.00 25.86  ? 565 GLU C N   1 
ATOM   8124  C CA  . GLU C 1 363 ? -17.036 -0.770  41.924 1.00 24.15  ? 565 GLU C CA  1 
ATOM   8125  C C   . GLU C 1 363 ? -18.252 -1.451  42.527 1.00 20.39  ? 565 GLU C C   1 
ATOM   8126  O O   . GLU C 1 363 ? -18.196 -2.598  42.955 1.00 20.25  ? 565 GLU C O   1 
ATOM   8127  C CB  . GLU C 1 363 ? -16.300 0.008   43.014 1.00 18.04  ? 565 GLU C CB  1 
ATOM   8128  C CG  . GLU C 1 363 ? -14.859 0.347   42.689 1.00 25.86  ? 565 GLU C CG  1 
ATOM   8129  C CD  . GLU C 1 363 ? -14.700 1.743   42.139 1.00 30.07  ? 565 GLU C CD  1 
ATOM   8130  O OE1 . GLU C 1 363 ? -15.487 2.127   41.259 1.00 30.24  ? 565 GLU C OE1 1 
ATOM   8131  O OE2 . GLU C 1 363 ? -13.787 2.461   42.589 1.00 32.93  ? 565 GLU C OE2 1 
ATOM   8132  N N   . ILE C 1 364 ? -19.362 -0.727  42.542 1.00 23.39  ? 566 ILE C N   1 
ATOM   8133  C CA  . ILE C 1 364 ? -20.600 -1.177  43.153 1.00 18.52  ? 566 ILE C CA  1 
ATOM   8134  C C   . ILE C 1 364 ? -21.513 -1.976  42.241 1.00 17.22  ? 566 ILE C C   1 
ATOM   8135  O O   . ILE C 1 364 ? -22.645 -2.255  42.588 1.00 16.51  ? 566 ILE C O   1 
ATOM   8136  C CB  . ILE C 1 364 ? -21.379 -0.005  43.757 1.00 19.27  ? 566 ILE C CB  1 
ATOM   8137  C CG1 . ILE C 1 364 ? -21.840 0.948   42.667 1.00 17.64  ? 566 ILE C CG1 1 
ATOM   8138  C CG2 . ILE C 1 364 ? -20.525 0.734   44.768 1.00 18.83  ? 566 ILE C CG2 1 
ATOM   8139  C CD1 . ILE C 1 364 ? -22.689 2.070   43.207 1.00 15.70  ? 566 ILE C CD1 1 
ATOM   8140  N N   . LYS C 1 365 ? -21.008 -2.344  41.076 1.00 20.20  ? 567 LYS C N   1 
ATOM   8141  C CA  . LYS C 1 365 ? -21.734 -3.122  40.084 1.00 19.37  ? 567 LYS C CA  1 
ATOM   8142  C C   . LYS C 1 365 ? -22.174 -4.499  40.577 1.00 18.39  ? 567 LYS C C   1 
ATOM   8143  O O   . LYS C 1 365 ? -23.183 -5.018  40.127 1.00 18.27  ? 567 LYS C O   1 
ATOM   8144  C CB  . LYS C 1 365 ? -20.879 -3.275  38.839 1.00 17.52  ? 567 LYS C CB  1 
ATOM   8145  C CG  . LYS C 1 365 ? -21.316 -4.378  37.908 1.00 20.40  ? 567 LYS C CG  1 
ATOM   8146  C CD  . LYS C 1 365 ? -20.237 -4.587  36.873 1.00 25.07  ? 567 LYS C CD  1 
ATOM   8147  C CE  . LYS C 1 365 ? -18.892 -4.654  37.563 1.00 26.56  ? 567 LYS C CE  1 
ATOM   8148  N NZ  . LYS C 1 365 ? -17.824 -4.043  36.734 1.00 29.02  ? 567 LYS C NZ  1 
ATOM   8149  N N   . THR C 1 366 ? -21.386 -5.116  41.445 1.00 20.45  ? 568 THR C N   1 
ATOM   8150  C CA  . THR C 1 366 ? -21.714 -6.433  41.986 1.00 18.82  ? 568 THR C CA  1 
ATOM   8151  C C   . THR C 1 366 ? -23.014 -6.507  42.800 1.00 18.54  ? 568 THR C C   1 
ATOM   8152  O O   . THR C 1 366 ? -23.708 -7.502  42.729 1.00 18.12  ? 568 THR C O   1 
ATOM   8153  C CB  . THR C 1 366 ? -20.551 -7.016  42.809 1.00 17.63  ? 568 THR C CB  1 
ATOM   8154  O OG1 . THR C 1 366 ? -20.048 -6.021  43.701 1.00 20.25  ? 568 THR C OG1 1 
ATOM   8155  C CG2 . THR C 1 366 ? -19.436 -7.454  41.901 1.00 16.78  ? 568 THR C CG2 1 
ATOM   8156  N N   . THR C 1 367 ? -23.320 -5.505  43.615 1.00 17.58  ? 569 THR C N   1 
ATOM   8157  C CA  . THR C 1 367 ? -24.567 -5.532  44.386 1.00 17.35  ? 569 THR C CA  1 
ATOM   8158  C C   . THR C 1 367 ? -25.663 -4.612  43.858 1.00 16.74  ? 569 THR C C   1 
ATOM   8159  O O   . THR C 1 367 ? -26.823 -4.772  44.215 1.00 16.84  ? 569 THR C O   1 
ATOM   8160  C CB  . THR C 1 367 ? -24.355 -5.169  45.871 1.00 18.10  ? 569 THR C CB  1 
ATOM   8161  O OG1 . THR C 1 367 ? -23.611 -3.952  45.969 1.00 19.55  ? 569 THR C OG1 1 
ATOM   8162  C CG2 . THR C 1 367 ? -23.619 -6.269  46.599 1.00 18.15  ? 569 THR C CG2 1 
ATOM   8163  N N   . ASN C 1 368 ? -25.300 -3.651  43.017 1.00 15.78  ? 570 ASN C N   1 
ATOM   8164  C CA  . ASN C 1 368 ? -26.269 -2.696  42.487 1.00 15.74  ? 570 ASN C CA  1 
ATOM   8165  C C   . ASN C 1 368 ? -26.551 -2.880  41.011 1.00 16.70  ? 570 ASN C C   1 
ATOM   8166  O O   . ASN C 1 368 ? -25.691 -3.314  40.259 1.00 18.13  ? 570 ASN C O   1 
ATOM   8167  C CB  . ASN C 1 368 ? -25.754 -1.263  42.645 1.00 15.03  ? 570 ASN C CB  1 
ATOM   8168  C CG  . ASN C 1 368 ? -25.473 -0.884  44.078 1.00 15.74  ? 570 ASN C CG  1 
ATOM   8169  O OD1 . ASN C 1 368 ? -24.891 -1.645  44.832 1.00 16.33  ? 570 ASN C OD1 1 
ATOM   8170  N ND2 . ASN C 1 368 ? -25.863 0.315   44.449 1.00 16.45  ? 570 ASN C ND2 1 
ATOM   8171  N N   . PRO C 1 369 ? -27.771 -2.551  40.582 1.00 15.31  ? 571 PRO C N   1 
ATOM   8172  C CA  . PRO C 1 369 ? -28.049 -2.612  39.148 1.00 15.41  ? 571 PRO C CA  1 
ATOM   8173  C C   . PRO C 1 369 ? -27.360 -1.480  38.409 1.00 15.76  ? 571 PRO C C   1 
ATOM   8174  O O   . PRO C 1 369 ? -27.035 -0.436  38.978 1.00 15.87  ? 571 PRO C O   1 
ATOM   8175  C CB  . PRO C 1 369 ? -29.574 -2.473  39.084 1.00 15.44  ? 571 PRO C CB  1 
ATOM   8176  C CG  . PRO C 1 369 ? -29.920 -1.718  40.304 1.00 15.39  ? 571 PRO C CG  1 
ATOM   8177  C CD  . PRO C 1 369 ? -28.951 -2.129  41.357 1.00 15.03  ? 571 PRO C CD  1 
ATOM   8178  N N   . VAL C 1 370 ? -27.122 -1.709  37.119 1.00 17.71  ? 572 VAL C N   1 
ATOM   8179  C CA  . VAL C 1 370 ? -26.495 -0.693  36.286 1.00 17.09  ? 572 VAL C CA  1 
ATOM   8180  C C   . VAL C 1 370 ? -27.444 0.486   36.126 1.00 17.51  ? 572 VAL C C   1 
ATOM   8181  O O   . VAL C 1 370 ? -28.658 0.312   35.955 1.00 17.30  ? 572 VAL C O   1 
ATOM   8182  C CB  . VAL C 1 370 ? -26.098 -1.291  34.927 1.00 16.27  ? 572 VAL C CB  1 
ATOM   8183  C CG1 . VAL C 1 370 ? -25.537 -0.219  34.019 1.00 15.97  ? 572 VAL C CG1 1 
ATOM   8184  C CG2 . VAL C 1 370 ? -25.094 -2.406  35.127 1.00 15.86  ? 572 VAL C CG2 1 
ATOM   8185  N N   . ALA C 1 371 ? -26.891 1.700   36.195 1.00 17.96  ? 573 ALA C N   1 
ATOM   8186  C CA  . ALA C 1 371 ? -27.719 2.900   36.180 1.00 18.03  ? 573 ALA C CA  1 
ATOM   8187  C C   . ALA C 1 371 ? -28.538 3.018   34.905 1.00 18.63  ? 573 ALA C C   1 
ATOM   8188  O O   . ALA C 1 371 ? -29.653 3.550   34.930 1.00 17.99  ? 573 ALA C O   1 
ATOM   8189  C CB  . ALA C 1 371 ? -26.846 4.141   36.348 1.00 18.37  ? 573 ALA C CB  1 
ATOM   8190  N N   . THR C 1 372 ? -28.007 2.538   33.788 1.00 19.84  ? 574 THR C N   1 
ATOM   8191  C CA  . THR C 1 372 ? -28.620 2.709   32.483 1.00 20.33  ? 574 THR C CA  1 
ATOM   8192  C C   . THR C 1 372 ? -29.468 1.516   32.058 1.00 21.22  ? 574 THR C C   1 
ATOM   8193  O O   . THR C 1 372 ? -29.929 1.478   30.915 1.00 22.42  ? 574 THR C O   1 
ATOM   8194  C CB  . THR C 1 372 ? -27.536 2.986   31.449 1.00 18.16  ? 574 THR C CB  1 
ATOM   8195  O OG1 . THR C 1 372 ? -26.645 1.869   31.384 1.00 18.17  ? 574 THR C OG1 1 
ATOM   8196  C CG2 . THR C 1 372 ? -26.750 4.200   31.877 1.00 17.63  ? 574 THR C CG2 1 
ATOM   8197  N N   . GLU C 1 373 ? -29.667 0.540   32.935 1.00 22.23  ? 575 GLU C N   1 
ATOM   8198  C CA  . GLU C 1 373 ? -30.418 -0.667  32.628 1.00 23.76  ? 575 GLU C CA  1 
ATOM   8199  C C   . GLU C 1 373 ? -31.675 -0.745  33.485 1.00 22.32  ? 575 GLU C C   1 
ATOM   8200  O O   . GLU C 1 373 ? -31.768 -0.128  34.547 1.00 22.02  ? 575 GLU C O   1 
ATOM   8201  C CB  . GLU C 1 373 ? -29.567 -1.918  32.864 1.00 19.78  ? 575 GLU C CB  1 
ATOM   8202  C CG  . GLU C 1 373 ? -28.337 -2.030  31.993 1.00 26.78  ? 575 GLU C CG  1 
ATOM   8203  C CD  . GLU C 1 373 ? -28.660 -2.051  30.519 1.00 31.13  ? 575 GLU C CD  1 
ATOM   8204  O OE1 . GLU C 1 373 ? -29.673 -2.674  30.138 1.00 33.67  ? 575 GLU C OE1 1 
ATOM   8205  O OE2 . GLU C 1 373 ? -27.894 -1.453  29.738 1.00 33.78  ? 575 GLU C OE2 1 
ATOM   8206  N N   . SER C 1 374 ? -32.646 -1.516  33.006 1.00 23.21  ? 576 SER C N   1 
ATOM   8207  C CA  . SER C 1 374 ? -33.853 -1.765  33.780 1.00 23.11  ? 576 SER C CA  1 
ATOM   8208  C C   . SER C 1 374 ? -33.553 -2.678  34.963 1.00 22.47  ? 576 SER C C   1 
ATOM   8209  O O   . SER C 1 374 ? -32.668 -3.534  34.908 1.00 23.29  ? 576 SER C O   1 
ATOM   8210  C CB  . SER C 1 374 ? -34.932 -2.397  32.906 1.00 23.46  ? 576 SER C CB  1 
ATOM   8211  O OG  . SER C 1 374 ? -35.344 -1.513  31.885 1.00 26.86  ? 576 SER C OG  1 
ATOM   8212  N N   . TYR C 1 375 ? -34.314 -2.490  36.042 1.00 21.79  ? 577 TYR C N   1 
ATOM   8213  C CA  . TYR C 1 375 ? -34.133 -3.321  37.226 1.00 20.54  ? 577 TYR C CA  1 
ATOM   8214  C C   . TYR C 1 375 ? -34.429 -4.783  36.926 1.00 20.95  ? 577 TYR C C   1 
ATOM   8215  O O   . TYR C 1 375 ? -33.767 -5.680  37.457 1.00 20.60  ? 577 TYR C O   1 
ATOM   8216  C CB  . TYR C 1 375 ? -35.028 -2.822  38.360 1.00 22.55  ? 577 TYR C CB  1 
ATOM   8217  C CG  . TYR C 1 375 ? -34.981 -3.688  39.597 1.00 21.75  ? 577 TYR C CG  1 
ATOM   8218  C CD1 . TYR C 1 375 ? -33.932 -3.589  40.497 1.00 21.82  ? 577 TYR C CD1 1 
ATOM   8219  C CD2 . TYR C 1 375 ? -35.980 -4.613  39.858 1.00 20.78  ? 577 TYR C CD2 1 
ATOM   8220  C CE1 . TYR C 1 375 ? -33.881 -4.380  41.622 1.00 21.71  ? 577 TYR C CE1 1 
ATOM   8221  C CE2 . TYR C 1 375 ? -35.935 -5.409  40.981 1.00 20.22  ? 577 TYR C CE2 1 
ATOM   8222  C CZ  . TYR C 1 375 ? -34.882 -5.287  41.859 1.00 20.77  ? 577 TYR C CZ  1 
ATOM   8223  O OH  . TYR C 1 375 ? -34.828 -6.072  42.983 1.00 21.03  ? 577 TYR C OH  1 
ATOM   8224  N N   . GLY C 1 376 ? -35.413 -5.042  36.073 1.00 23.75  ? 578 GLY C N   1 
ATOM   8225  C CA  . GLY C 1 376 ? -35.843 -6.405  35.833 1.00 23.37  ? 578 GLY C CA  1 
ATOM   8226  C C   . GLY C 1 376 ? -37.115 -6.422  35.011 1.00 23.86  ? 578 GLY C C   1 
ATOM   8227  O O   . GLY C 1 376 ? -37.388 -5.495  34.250 1.00 23.65  ? 578 GLY C O   1 
ATOM   8228  N N   . GLN C 1 377 ? -37.873 -7.504  35.166 1.00 26.38  ? 579 GLN C N   1 
ATOM   8229  C CA  . GLN C 1 377 ? -39.135 -7.692  34.470 1.00 27.48  ? 579 GLN C CA  1 
ATOM   8230  C C   . GLN C 1 377 ? -40.198 -8.181  35.442 1.00 26.59  ? 579 GLN C C   1 
ATOM   8231  O O   . GLN C 1 377 ? -39.905 -8.902  36.396 1.00 26.51  ? 579 GLN C O   1 
ATOM   8232  C CB  . GLN C 1 377 ? -39.009 -8.700  33.328 1.00 26.53  ? 579 GLN C CB  1 
ATOM   8233  C CG  . GLN C 1 377 ? -38.148 -8.252  32.173 1.00 32.86  ? 579 GLN C CG  1 
ATOM   8234  C CD  . GLN C 1 377 ? -38.032 -9.321  31.113 1.00 38.15  ? 579 GLN C CD  1 
ATOM   8235  O OE1 . GLN C 1 377 ? -38.168 -10.508 31.400 1.00 41.34  ? 579 GLN C OE1 1 
ATOM   8236  N NE2 . GLN C 1 377 ? -37.798 -8.908  29.878 1.00 39.61  ? 579 GLN C NE2 1 
ATOM   8237  N N   . VAL C 1 378 ? -41.440 -7.775  35.187 1.00 30.53  ? 580 VAL C N   1 
ATOM   8238  C CA  . VAL C 1 378 ? -42.599 -8.253  35.926 1.00 30.43  ? 580 VAL C CA  1 
ATOM   8239  C C   . VAL C 1 378 ? -43.643 -8.725  34.930 1.00 31.18  ? 580 VAL C C   1 
ATOM   8240  O O   . VAL C 1 378 ? -43.694 -8.271  33.786 1.00 30.91  ? 580 VAL C O   1 
ATOM   8241  C CB  . VAL C 1 378 ? -43.207 -7.178  36.848 1.00 27.52  ? 580 VAL C CB  1 
ATOM   8242  C CG1 . VAL C 1 378 ? -42.276 -6.862  37.979 1.00 27.95  ? 580 VAL C CG1 1 
ATOM   8243  C CG2 . VAL C 1 378 ? -43.503 -5.922  36.054 1.00 26.46  ? 580 VAL C CG2 1 
ATOM   8244  N N   . ALA C 1 379 ? -44.488 -9.644  35.384 1.00 33.93  ? 581 ALA C N   1 
ATOM   8245  C CA  . ALA C 1 379 ? -45.611 -10.104 34.583 1.00 35.37  ? 581 ALA C CA  1 
ATOM   8246  C C   . ALA C 1 379 ? -46.718 -9.060  34.622 1.00 36.38  ? 581 ALA C C   1 
ATOM   8247  O O   . ALA C 1 379 ? -47.048 -8.534  35.688 1.00 36.02  ? 581 ALA C O   1 
ATOM   8248  C CB  . ALA C 1 379 ? -46.121 -11.447 35.099 1.00 35.51  ? 581 ALA C CB  1 
ATOM   8249  N N   . THR C 1 380 ? -47.338 -8.777  33.489 1.00 37.08  ? 582 THR C N   1 
ATOM   8250  C CA  . THR C 1 380 ? -48.400 -7.785  33.496 1.00 37.74  ? 582 THR C CA  1 
ATOM   8251  C C   . THR C 1 380 ? -49.774 -8.368  33.184 1.00 39.00  ? 582 THR C C   1 
ATOM   8252  O O   . THR C 1 380 ? -50.737 -7.632  33.015 1.00 39.64  ? 582 THR C O   1 
ATOM   8253  C CB  . THR C 1 380 ? -48.084 -6.628  32.537 1.00 38.53  ? 582 THR C CB  1 
ATOM   8254  O OG1 . THR C 1 380 ? -47.713 -7.154  31.260 1.00 40.19  ? 582 THR C OG1 1 
ATOM   8255  C CG2 . THR C 1 380 ? -46.939 -5.806  33.079 1.00 36.37  ? 582 THR C CG2 1 
ATOM   8256  N N   . ASN C 1 381 ? -49.865 -9.689  33.116 1.00 42.03  ? 583 ASN C N   1 
ATOM   8257  C CA  . ASN C 1 381 ? -51.128 -10.344 32.800 1.00 42.91  ? 583 ASN C CA  1 
ATOM   8258  C C   . ASN C 1 381 ? -51.154 -11.791 33.267 1.00 44.18  ? 583 ASN C C   1 
ATOM   8259  O O   . ASN C 1 381 ? -50.135 -12.322 33.694 1.00 44.42  ? 583 ASN C O   1 
ATOM   8260  C CB  . ASN C 1 381 ? -51.389 -10.292 31.298 1.00 45.64  ? 583 ASN C CB  1 
ATOM   8261  C CG  . ASN C 1 381 ? -50.633 -11.358 30.543 1.00 45.92  ? 583 ASN C CG  1 
ATOM   8262  O OD1 . ASN C 1 381 ? -49.643 -11.893 31.028 1.00 47.36  ? 583 ASN C OD1 1 
ATOM   8263  N ND2 . ASN C 1 381 ? -51.101 -11.677 29.351 1.00 46.15  ? 583 ASN C ND2 1 
ATOM   8264  N N   . HIS C 1 382 ? -52.323 -12.421 33.211 1.00 48.48  ? 584 HIS C N   1 
ATOM   8265  C CA  . HIS C 1 382 ? -52.438 -13.824 33.588 1.00 49.12  ? 584 HIS C CA  1 
ATOM   8266  C C   . HIS C 1 382 ? -52.344 -14.665 32.325 1.00 48.76  ? 584 HIS C C   1 
ATOM   8267  O O   . HIS C 1 382 ? -53.127 -14.480 31.403 1.00 48.96  ? 584 HIS C O   1 
ATOM   8268  C CB  . HIS C 1 382 ? -53.789 -14.113 34.238 1.00 44.49  ? 584 HIS C CB  1 
ATOM   8269  C CG  . HIS C 1 382 ? -53.902 -13.643 35.651 1.00 47.85  ? 584 HIS C CG  1 
ATOM   8270  N ND1 . HIS C 1 382 ? -55.033 -13.024 36.138 1.00 49.39  ? 584 HIS C ND1 1 
ATOM   8271  C CD2 . HIS C 1 382 ? -53.033 -13.704 36.685 1.00 50.07  ? 584 HIS C CD2 1 
ATOM   8272  C CE1 . HIS C 1 382 ? -54.854 -12.724 37.411 1.00 50.62  ? 584 HIS C CE1 1 
ATOM   8273  N NE2 . HIS C 1 382 ? -53.648 -13.123 37.767 1.00 51.99  ? 584 HIS C NE2 1 
ATOM   8274  N N   . GLN C 1 383 ? -51.388 -15.583 32.265 1.00 52.85  ? 585 GLN C N   1 
ATOM   8275  C CA  . GLN C 1 383 ? -51.279 -16.437 31.094 1.00 52.01  ? 585 GLN C CA  1 
ATOM   8276  C C   . GLN C 1 383 ? -52.474 -17.382 31.093 1.00 52.29  ? 585 GLN C C   1 
ATOM   8277  O O   . GLN C 1 383 ? -52.938 -17.823 32.141 1.00 52.07  ? 585 GLN C O   1 
ATOM   8278  C CB  . GLN C 1 383 ? -49.955 -17.197 31.066 1.00 52.83  ? 585 GLN C CB  1 
ATOM   8279  C CG  . GLN C 1 383 ? -49.750 -18.144 32.230 1.00 51.05  ? 585 GLN C CG  1 
ATOM   8280  C CD  . GLN C 1 383 ? -50.512 -19.439 32.066 1.00 49.89  ? 585 GLN C CD  1 
ATOM   8281  O OE1 . GLN C 1 383 ? -50.694 -19.927 30.955 1.00 49.66  ? 585 GLN C OE1 1 
ATOM   8282  N NE2 . GLN C 1 383 ? -50.954 -20.008 33.177 1.00 49.30  ? 585 GLN C NE2 1 
ATOM   8283  N N   . SER C 1 384 ? -52.974 -17.693 29.910 1.00 52.69  ? 586 SER C N   1 
ATOM   8284  C CA  . SER C 1 384 ? -54.139 -18.549 29.774 1.00 53.29  ? 586 SER C CA  1 
ATOM   8285  C C   . SER C 1 384 ? -54.121 -19.206 28.415 1.00 53.78  ? 586 SER C C   1 
ATOM   8286  O O   . SER C 1 384 ? -53.233 -18.959 27.614 1.00 53.16  ? 586 SER C O   1 
ATOM   8287  C CB  . SER C 1 384 ? -55.416 -17.732 29.925 1.00 54.84  ? 586 SER C CB  1 
ATOM   8288  O OG  . SER C 1 384 ? -55.557 -16.822 28.850 1.00 54.31  ? 586 SER C OG  1 
ATOM   8289  N N   . ALA C 1 385 ? -55.086 -20.072 28.142 1.00 55.39  ? 587 ALA C N   1 
ATOM   8290  C CA  . ALA C 1 385 ? -55.126 -20.703 26.832 1.00 56.57  ? 587 ALA C CA  1 
ATOM   8291  C C   . ALA C 1 385 ? -55.307 -19.632 25.754 1.00 58.01  ? 587 ALA C C   1 
ATOM   8292  O O   . ALA C 1 385 ? -54.644 -19.664 24.720 1.00 58.09  ? 587 ALA C O   1 
ATOM   8293  C CB  . ALA C 1 385 ? -56.255 -21.717 26.773 1.00 55.84  ? 587 ALA C CB  1 
ATOM   8294  N N   . GLN C 1 386 ? -56.207 -18.687 26.003 1.00 53.55  ? 588 GLN C N   1 
ATOM   8295  C CA  . GLN C 1 386 ? -56.458 -17.574 25.099 1.00 55.65  ? 588 GLN C CA  1 
ATOM   8296  C C   . GLN C 1 386 ? -55.291 -16.590 24.926 1.00 55.64  ? 588 GLN C C   1 
ATOM   8297  O O   . GLN C 1 386 ? -55.041 -16.128 23.816 1.00 56.81  ? 588 GLN C O   1 
ATOM   8298  C CB  . GLN C 1 386 ? -57.710 -16.815 25.539 1.00 59.65  ? 588 GLN C CB  1 
ATOM   8299  C CG  . GLN C 1 386 ? -58.995 -17.621 25.435 1.00 59.65  ? 588 GLN C CG  1 
ATOM   8300  C CD  . GLN C 1 386 ? -59.195 -18.568 26.601 1.00 59.65  ? 588 GLN C CD  1 
ATOM   8301  O OE1 . GLN C 1 386 ? -58.755 -18.298 27.718 1.00 59.65  ? 588 GLN C OE1 1 
ATOM   8302  N NE2 . GLN C 1 386 ? -59.872 -19.682 26.349 1.00 59.65  ? 588 GLN C NE2 1 
ATOM   8303  N N   . ALA C 1 387 ? -54.585 -16.264 26.010 1.00 54.73  ? 589 ALA C N   1 
ATOM   8304  C CA  . ALA C 1 387 ? -53.495 -15.278 25.942 1.00 52.88  ? 589 ALA C CA  1 
ATOM   8305  C C   . ALA C 1 387 ? -52.098 -15.673 26.439 1.00 51.85  ? 589 ALA C C   1 
ATOM   8306  O O   . ALA C 1 387 ? -51.942 -16.215 27.521 1.00 52.26  ? 589 ALA C O   1 
ATOM   8307  C CB  . ALA C 1 387 ? -53.930 -13.993 26.626 1.00 53.60  ? 589 ALA C CB  1 
ATOM   8308  N N   . GLN C 1 388 ? -51.085 -15.331 25.647 1.00 51.65  ? 590 GLN C N   1 
ATOM   8309  C CA  . GLN C 1 388 ? -49.680 -15.600 25.959 1.00 51.58  ? 590 GLN C CA  1 
ATOM   8310  C C   . GLN C 1 388 ? -49.161 -14.787 27.140 1.00 50.50  ? 590 GLN C C   1 
ATOM   8311  O O   . GLN C 1 388 ? -49.657 -13.702 27.417 1.00 49.96  ? 590 GLN C O   1 
ATOM   8312  C CB  . GLN C 1 388 ? -48.808 -15.265 24.757 1.00 55.05  ? 590 GLN C CB  1 
ATOM   8313  C CG  . GLN C 1 388 ? -48.713 -16.341 23.698 1.00 55.05  ? 590 GLN C CG  1 
ATOM   8314  C CD  . GLN C 1 388 ? -47.559 -16.085 22.754 1.00 55.05  ? 590 GLN C CD  1 
ATOM   8315  O OE1 . GLN C 1 388 ? -47.069 -14.961 22.651 1.00 55.05  ? 590 GLN C OE1 1 
ATOM   8316  N NE2 . GLN C 1 388 ? -47.113 -17.126 22.064 1.00 55.05  ? 590 GLN C NE2 1 
ATOM   8317  N N   . ALA C 1 389 ? -48.170 -15.324 27.844 1.00 48.90  ? 591 ALA C N   1 
ATOM   8318  C CA  . ALA C 1 389 ? -47.575 -14.633 28.985 1.00 48.66  ? 591 ALA C CA  1 
ATOM   8319  C C   . ALA C 1 389 ? -46.834 -13.381 28.537 1.00 48.48  ? 591 ALA C C   1 
ATOM   8320  O O   . ALA C 1 389 ? -46.106 -13.406 27.552 1.00 48.13  ? 591 ALA C O   1 
ATOM   8321  C CB  . ALA C 1 389 ? -46.636 -15.562 29.734 1.00 48.68  ? 591 ALA C CB  1 
ATOM   8322  N N   . GLN C 1 390 ? -47.009 -12.291 29.272 1.00 44.13  ? 592 GLN C N   1 
ATOM   8323  C CA  . GLN C 1 390 ? -46.360 -11.034 28.929 1.00 44.63  ? 592 GLN C CA  1 
ATOM   8324  C C   . GLN C 1 390 ? -45.662 -10.359 30.097 1.00 44.43  ? 592 GLN C C   1 
ATOM   8325  O O   . GLN C 1 390 ? -46.167 -10.337 31.212 1.00 43.85  ? 592 GLN C O   1 
ATOM   8326  C CB  . GLN C 1 390 ? -47.373 -10.069 28.331 1.00 47.73  ? 592 GLN C CB  1 
ATOM   8327  C CG  . GLN C 1 390 ? -47.845 -10.462 26.950 1.00 47.73  ? 592 GLN C CG  1 
ATOM   8328  C CD  . GLN C 1 390 ? -49.214 -9.910  26.643 1.00 47.73  ? 592 GLN C CD  1 
ATOM   8329  O OE1 . GLN C 1 390 ? -49.899 -9.398  27.525 1.00 47.73  ? 592 GLN C OE1 1 
ATOM   8330  N NE2 . GLN C 1 390 ? -49.624 -10.011 25.387 1.00 47.73  ? 592 GLN C NE2 1 
ATOM   8331  N N   . THR C 1 391 ? -44.496 -9.793  29.820 1.00 40.35  ? 593 THR C N   1 
ATOM   8332  C CA  . THR C 1 391 ? -43.734 -9.087  30.830 1.00 40.63  ? 593 THR C CA  1 
ATOM   8333  C C   . THR C 1 391 ? -43.429 -7.688  30.336 1.00 39.10  ? 593 THR C C   1 
ATOM   8334  O O   . THR C 1 391 ? -43.527 -7.398  29.151 1.00 39.21  ? 593 THR C O   1 
ATOM   8335  C CB  . THR C 1 391 ? -42.403 -9.791  31.165 1.00 39.90  ? 593 THR C CB  1 
ATOM   8336  O OG1 . THR C 1 391 ? -41.745 -10.177 29.955 1.00 42.34  ? 593 THR C OG1 1 
ATOM   8337  C CG2 . THR C 1 391 ? -42.636 -11.022 32.022 1.00 39.40  ? 593 THR C CG2 1 
ATOM   8338  N N   . GLY C 1 392 ? -43.066 -6.824  31.269 1.00 31.98  ? 594 GLY C N   1 
ATOM   8339  C CA  . GLY C 1 392 ? -42.711 -5.446  30.979 1.00 30.06  ? 594 GLY C CA  1 
ATOM   8340  C C   . GLY C 1 392 ? -41.584 -5.003  31.880 1.00 29.02  ? 594 GLY C C   1 
ATOM   8341  O O   . GLY C 1 392 ? -41.382 -5.558  32.958 1.00 29.11  ? 594 GLY C O   1 
ATOM   8342  N N   . TRP C 1 393 ? -40.859 -3.987  31.432 1.00 26.11  ? 595 TRP C N   1 
ATOM   8343  C CA  . TRP C 1 393 ? -39.599 -3.644  32.069 1.00 25.43  ? 595 TRP C CA  1 
ATOM   8344  C C   . TRP C 1 393 ? -39.824 -2.711  33.247 1.00 23.71  ? 595 TRP C C   1 
ATOM   8345  O O   . TRP C 1 393 ? -40.689 -1.833  33.212 1.00 23.68  ? 595 TRP C O   1 
ATOM   8346  C CB  . TRP C 1 393 ? -38.660 -2.995  31.059 1.00 23.17  ? 595 TRP C CB  1 
ATOM   8347  C CG  . TRP C 1 393 ? -38.224 -3.917  29.968 1.00 26.97  ? 595 TRP C CG  1 
ATOM   8348  C CD1 . TRP C 1 393 ? -38.768 -4.024  28.726 1.00 27.66  ? 595 TRP C CD1 1 
ATOM   8349  C CD2 . TRP C 1 393 ? -37.156 -4.868  30.023 1.00 29.31  ? 595 TRP C CD2 1 
ATOM   8350  N NE1 . TRP C 1 393 ? -38.102 -4.978  27.999 1.00 29.13  ? 595 TRP C NE1 1 
ATOM   8351  C CE2 . TRP C 1 393 ? -37.108 -5.512  28.774 1.00 29.65  ? 595 TRP C CE2 1 
ATOM   8352  C CE3 . TRP C 1 393 ? -36.234 -5.236  31.006 1.00 31.31  ? 595 TRP C CE3 1 
ATOM   8353  C CZ2 . TRP C 1 393 ? -36.175 -6.500  28.481 1.00 30.42  ? 595 TRP C CZ2 1 
ATOM   8354  C CZ3 . TRP C 1 393 ? -35.311 -6.218  30.714 1.00 32.74  ? 595 TRP C CZ3 1 
ATOM   8355  C CH2 . TRP C 1 393 ? -35.287 -6.838  29.462 1.00 32.06  ? 595 TRP C CH2 1 
ATOM   8356  N N   . VAL C 1 394 ? -39.035 -2.904  34.296 1.00 24.33  ? 596 VAL C N   1 
ATOM   8357  C CA  . VAL C 1 394 ? -39.077 -2.055  35.477 1.00 22.70  ? 596 VAL C CA  1 
ATOM   8358  C C   . VAL C 1 394 ? -38.018 -0.982  35.276 1.00 22.86  ? 596 VAL C C   1 
ATOM   8359  O O   . VAL C 1 394 ? -36.818 -1.259  35.312 1.00 22.34  ? 596 VAL C O   1 
ATOM   8360  C CB  . VAL C 1 394 ? -38.838 -2.854  36.759 1.00 22.16  ? 596 VAL C CB  1 
ATOM   8361  C CG1 . VAL C 1 394 ? -38.744 -1.924  37.940 1.00 20.71  ? 596 VAL C CG1 1 
ATOM   8362  C CG2 . VAL C 1 394 ? -39.945 -3.862  36.961 1.00 20.09  ? 596 VAL C CG2 1 
ATOM   8363  N N   . GLN C 1 395 ? -38.463 0.253   35.056 1.00 22.46  ? 597 GLN C N   1 
ATOM   8364  C CA  . GLN C 1 395 ? -37.516 1.340   34.858 1.00 23.20  ? 597 GLN C CA  1 
ATOM   8365  C C   . GLN C 1 395 ? -37.016 1.873   36.191 1.00 23.53  ? 597 GLN C C   1 
ATOM   8366  O O   . GLN C 1 395 ? -35.890 2.373   36.283 1.00 24.45  ? 597 GLN C O   1 
ATOM   8367  C CB  . GLN C 1 395 ? -38.163 2.446   34.033 1.00 22.87  ? 597 GLN C CB  1 
ATOM   8368  C CG  . GLN C 1 395 ? -38.664 1.967   32.689 1.00 24.22  ? 597 GLN C CG  1 
ATOM   8369  C CD  . GLN C 1 395 ? -37.581 1.324   31.861 1.00 23.04  ? 597 GLN C CD  1 
ATOM   8370  O OE1 . GLN C 1 395 ? -36.446 1.787   31.839 1.00 24.47  ? 597 GLN C OE1 1 
ATOM   8371  N NE2 . GLN C 1 395 ? -37.923 0.241   31.181 1.00 22.59  ? 597 GLN C NE2 1 
ATOM   8372  N N   . ASN C 1 396 ? -37.838 1.776   37.230 1.00 22.64  ? 598 ASN C N   1 
ATOM   8373  C CA  . ASN C 1 396 ? -37.463 2.191   38.573 1.00 22.47  ? 598 ASN C CA  1 
ATOM   8374  C C   . ASN C 1 396 ? -38.091 1.248   39.584 1.00 22.09  ? 598 ASN C C   1 
ATOM   8375  O O   . ASN C 1 396 ? -39.252 0.857   39.437 1.00 23.29  ? 598 ASN C O   1 
ATOM   8376  C CB  . ASN C 1 396 ? -37.896 3.630   38.855 1.00 22.29  ? 598 ASN C CB  1 
ATOM   8377  C CG  . ASN C 1 396 ? -39.386 3.827   38.713 1.00 23.26  ? 598 ASN C CG  1 
ATOM   8378  O OD1 . ASN C 1 396 ? -40.071 3.052   38.051 1.00 24.06  ? 598 ASN C OD1 1 
ATOM   8379  N ND2 . ASN C 1 396 ? -39.903 4.854   39.365 1.00 22.83  ? 598 ASN C ND2 1 
ATOM   8380  N N   . GLN C 1 397 ? -37.327 0.893   40.611 1.00 24.01  ? 599 GLN C N   1 
ATOM   8381  C CA  . GLN C 1 397 ? -37.794 0.002   41.661 1.00 22.09  ? 599 GLN C CA  1 
ATOM   8382  C C   . GLN C 1 397 ? -37.400 0.574   43.009 1.00 22.04  ? 599 GLN C C   1 
ATOM   8383  O O   . GLN C 1 397 ? -36.216 0.799   43.267 1.00 22.58  ? 599 GLN C O   1 
ATOM   8384  C CB  . GLN C 1 397 ? -37.215 -1.404  41.492 1.00 23.02  ? 599 GLN C CB  1 
ATOM   8385  C CG  . GLN C 1 397 ? -37.689 -2.404  42.532 1.00 22.44  ? 599 GLN C CG  1 
ATOM   8386  C CD  . GLN C 1 397 ? -39.185 -2.623  42.500 1.00 22.77  ? 599 GLN C CD  1 
ATOM   8387  O OE1 . GLN C 1 397 ? -39.747 -2.997  41.475 1.00 24.91  ? 599 GLN C OE1 1 
ATOM   8388  N NE2 . GLN C 1 397 ? -39.838 -2.397  43.631 1.00 21.85  ? 599 GLN C NE2 1 
ATOM   8389  N N   . GLY C 1 398 ? -38.392 0.817   43.862 1.00 23.67  ? 600 GLY C N   1 
ATOM   8390  C CA  . GLY C 1 398 ? -38.138 1.258   45.214 1.00 22.25  ? 600 GLY C CA  1 
ATOM   8391  C C   . GLY C 1 398 ? -37.649 0.124   46.092 1.00 22.06  ? 600 GLY C C   1 
ATOM   8392  O O   . GLY C 1 398 ? -37.374 -0.983  45.639 1.00 21.62  ? 600 GLY C O   1 
ATOM   8393  N N   . ILE C 1 399 ? -37.541 0.422   47.386 1.00 23.10  ? 601 ILE C N   1 
ATOM   8394  C CA  . ILE C 1 399 ? -37.032 -0.559  48.334 1.00 22.38  ? 601 ILE C CA  1 
ATOM   8395  C C   . ILE C 1 399 ? -37.978 -1.747  48.417 1.00 21.96  ? 601 ILE C C   1 
ATOM   8396  O O   . ILE C 1 399 ? -39.204 -1.591  48.448 1.00 22.63  ? 601 ILE C O   1 
ATOM   8397  C CB  . ILE C 1 399 ? -36.828 0.088   49.710 1.00 22.83  ? 601 ILE C CB  1 
ATOM   8398  C CG1 . ILE C 1 399 ? -35.786 1.198   49.627 1.00 23.23  ? 601 ILE C CG1 1 
ATOM   8399  C CG2 . ILE C 1 399 ? -36.386 -0.936  50.712 1.00 24.29  ? 601 ILE C CG2 1 
ATOM   8400  C CD1 . ILE C 1 399 ? -34.436 0.711   49.190 1.00 22.09  ? 601 ILE C CD1 1 
ATOM   8401  N N   . LEU C 1 400 ? -37.406 -2.948  48.433 1.00 23.38  ? 602 LEU C N   1 
ATOM   8402  C CA  . LEU C 1 400 ? -38.112 -4.181  48.724 1.00 22.83  ? 602 LEU C CA  1 
ATOM   8403  C C   . LEU C 1 400 ? -37.449 -4.888  49.897 1.00 23.90  ? 602 LEU C C   1 
ATOM   8404  O O   . LEU C 1 400 ? -36.245 -4.726  50.116 1.00 23.57  ? 602 LEU C O   1 
ATOM   8405  C CB  . LEU C 1 400 ? -38.133 -5.125  47.516 1.00 23.81  ? 602 LEU C CB  1 
ATOM   8406  C CG  . LEU C 1 400 ? -38.955 -4.699  46.304 1.00 23.08  ? 602 LEU C CG  1 
ATOM   8407  C CD1 . LEU C 1 400 ? -38.732 -5.660  45.159 1.00 22.55  ? 602 LEU C CD1 1 
ATOM   8408  C CD2 . LEU C 1 400 ? -40.425 -4.645  46.661 1.00 22.04  ? 602 LEU C CD2 1 
ATOM   8409  N N   . PRO C 1 401 ? -38.206 -5.653  50.682 1.00 23.02  ? 603 PRO C N   1 
ATOM   8410  C CA  . PRO C 1 401 ? -37.575 -6.515  51.686 1.00 23.21  ? 603 PRO C CA  1 
ATOM   8411  C C   . PRO C 1 401 ? -36.622 -7.496  51.020 1.00 23.42  ? 603 PRO C C   1 
ATOM   8412  O O   . PRO C 1 401 ? -36.979 -8.181  50.060 1.00 23.83  ? 603 PRO C O   1 
ATOM   8413  C CB  . PRO C 1 401 ? -38.764 -7.230  52.333 1.00 21.76  ? 603 PRO C CB  1 
ATOM   8414  C CG  . PRO C 1 401 ? -39.901 -6.301  52.136 1.00 24.24  ? 603 PRO C CG  1 
ATOM   8415  C CD  . PRO C 1 401 ? -39.671 -5.651  50.803 1.00 22.90  ? 603 PRO C CD  1 
ATOM   8416  N N   . GLY C 1 402 ? -35.401 -7.557  51.534 1.00 23.64  ? 604 GLY C N   1 
ATOM   8417  C CA  . GLY C 1 402 ? -34.383 -8.409  50.970 1.00 22.61  ? 604 GLY C CA  1 
ATOM   8418  C C   . GLY C 1 402 ? -33.347 -7.715  50.114 1.00 22.46  ? 604 GLY C C   1 
ATOM   8419  O O   . GLY C 1 402 ? -32.412 -8.378  49.655 1.00 22.70  ? 604 GLY C O   1 
ATOM   8420  N N   . MET C 1 403 ? -33.482 -6.415  49.876 1.00 21.29  ? 605 MET C N   1 
ATOM   8421  C CA  . MET C 1 403 ? -32.498 -5.693  49.086 1.00 19.97  ? 605 MET C CA  1 
ATOM   8422  C C   . MET C 1 403 ? -31.269 -5.335  49.907 1.00 19.32  ? 605 MET C C   1 
ATOM   8423  O O   . MET C 1 403 ? -31.336 -5.137  51.122 1.00 19.90  ? 605 MET C O   1 
ATOM   8424  C CB  . MET C 1 403 ? -33.089 -4.417  48.490 1.00 16.62  ? 605 MET C CB  1 
ATOM   8425  C CG  . MET C 1 403 ? -34.022 -4.631  47.328 1.00 17.37  ? 605 MET C CG  1 
ATOM   8426  S SD  . MET C 1 403 ? -34.607 -3.061  46.685 1.00 20.04  ? 605 MET C SD  1 
ATOM   8427  C CE  . MET C 1 403 ? -35.581 -3.627  45.300 1.00 20.32  ? 605 MET C CE  1 
ATOM   8428  N N   . VAL C 1 404 ? -30.135 -5.249  49.215 1.00 20.15  ? 606 VAL C N   1 
ATOM   8429  C CA  . VAL C 1 404 ? -28.887 -4.733  49.758 1.00 19.69  ? 606 VAL C CA  1 
ATOM   8430  C C   . VAL C 1 404 ? -28.271 -3.834  48.697 1.00 19.79  ? 606 VAL C C   1 
ATOM   8431  O O   . VAL C 1 404 ? -28.480 -4.034  47.497 1.00 22.02  ? 606 VAL C O   1 
ATOM   8432  C CB  . VAL C 1 404 ? -27.914 -5.863  50.156 1.00 18.24  ? 606 VAL C CB  1 
ATOM   8433  C CG1 . VAL C 1 404 ? -28.491 -6.683  51.292 1.00 21.98  ? 606 VAL C CG1 1 
ATOM   8434  C CG2 . VAL C 1 404 ? -27.627 -6.749  48.969 1.00 17.32  ? 606 VAL C CG2 1 
ATOM   8435  N N   . TRP C 1 405 ? -27.520 -2.829  49.137 1.00 18.99  ? 607 TRP C N   1 
ATOM   8436  C CA  . TRP C 1 405 ? -26.939 -1.883  48.194 1.00 18.91  ? 607 TRP C CA  1 
ATOM   8437  C C   . TRP C 1 405 ? -25.706 -1.244  48.812 1.00 19.65  ? 607 TRP C C   1 
ATOM   8438  O O   . TRP C 1 405 ? -25.495 -1.288  50.025 1.00 19.31  ? 607 TRP C O   1 
ATOM   8439  C CB  . TRP C 1 405 ? -27.952 -0.810  47.780 1.00 17.41  ? 607 TRP C CB  1 
ATOM   8440  C CG  . TRP C 1 405 ? -28.412 0.064   48.904 1.00 17.91  ? 607 TRP C CG  1 
ATOM   8441  C CD1 . TRP C 1 405 ? -27.861 1.243   49.293 1.00 18.83  ? 607 TRP C CD1 1 
ATOM   8442  C CD2 . TRP C 1 405 ? -29.522 -0.166  49.777 1.00 17.88  ? 607 TRP C CD2 1 
ATOM   8443  N NE1 . TRP C 1 405 ? -28.551 1.762   50.357 1.00 18.35  ? 607 TRP C NE1 1 
ATOM   8444  C CE2 . TRP C 1 405 ? -29.577 0.914   50.674 1.00 18.76  ? 607 TRP C CE2 1 
ATOM   8445  C CE3 . TRP C 1 405 ? -30.472 -1.182  49.888 1.00 17.20  ? 607 TRP C CE3 1 
ATOM   8446  C CZ2 . TRP C 1 405 ? -30.544 1.007   51.669 1.00 18.28  ? 607 TRP C CZ2 1 
ATOM   8447  C CZ3 . TRP C 1 405 ? -31.428 -1.087  50.874 1.00 18.75  ? 607 TRP C CZ3 1 
ATOM   8448  C CH2 . TRP C 1 405 ? -31.458 -0.002  51.753 1.00 18.55  ? 607 TRP C CH2 1 
ATOM   8449  N N   . GLN C 1 406 ? -24.893 -0.646  47.945 1.00 18.70  ? 608 GLN C N   1 
ATOM   8450  C CA  . GLN C 1 406 ? -23.708 0.109   48.326 1.00 19.94  ? 608 GLN C CA  1 
ATOM   8451  C C   . GLN C 1 406 ? -23.961 1.594   48.125 1.00 20.40  ? 608 GLN C C   1 
ATOM   8452  O O   . GLN C 1 406 ? -24.586 1.993   47.138 1.00 19.59  ? 608 GLN C O   1 
ATOM   8453  C CB  . GLN C 1 406 ? -22.496 -0.329  47.503 1.00 14.79  ? 608 GLN C CB  1 
ATOM   8454  C CG  . GLN C 1 406 ? -21.922 -1.670  47.883 1.00 20.43  ? 608 GLN C CG  1 
ATOM   8455  C CD  . GLN C 1 406 ? -21.267 -1.642  49.243 1.00 24.08  ? 608 GLN C CD  1 
ATOM   8456  O OE1 . GLN C 1 406 ? -20.555 -0.701  49.579 1.00 27.36  ? 608 GLN C OE1 1 
ATOM   8457  N NE2 . GLN C 1 406 ? -21.514 -2.664  50.039 1.00 20.36  ? 608 GLN C NE2 1 
ATOM   8458  N N   . ASP C 1 407 ? -23.474 2.406   49.056 1.00 21.10  ? 609 ASP C N   1 
ATOM   8459  C CA  . ASP C 1 407 ? -23.552 3.849   48.909 1.00 21.88  ? 609 ASP C CA  1 
ATOM   8460  C C   . ASP C 1 407 ? -22.547 4.328   47.867 1.00 20.97  ? 609 ASP C C   1 
ATOM   8461  O O   . ASP C 1 407 ? -21.618 3.614   47.485 1.00 19.52  ? 609 ASP C O   1 
ATOM   8462  C CB  . ASP C 1 407 ? -23.298 4.544   50.245 1.00 22.49  ? 609 ASP C CB  1 
ATOM   8463  C CG  . ASP C 1 407 ? -24.422 4.323   51.241 1.00 27.86  ? 609 ASP C CG  1 
ATOM   8464  O OD1 . ASP C 1 407 ? -25.517 3.893   50.822 1.00 28.86  ? 609 ASP C OD1 1 
ATOM   8465  O OD2 . ASP C 1 407 ? -24.208 4.582   52.445 1.00 29.90  ? 609 ASP C OD2 1 
ATOM   8466  N N   . ARG C 1 408 ? -22.764 5.547   47.381 1.00 19.91  ? 610 ARG C N   1 
ATOM   8467  C CA  . ARG C 1 408 ? -21.834 6.140   46.431 1.00 20.25  ? 610 ARG C CA  1 
ATOM   8468  C C   . ARG C 1 408 ? -20.483 6.375   47.092 1.00 20.27  ? 610 ARG C C   1 
ATOM   8469  O O   . ARG C 1 408 ? -20.395 6.622   48.297 1.00 19.71  ? 610 ARG C O   1 
ATOM   8470  C CB  . ARG C 1 408 ? -22.395 7.450   45.883 1.00 17.01  ? 610 ARG C CB  1 
ATOM   8471  C CG  . ARG C 1 408 ? -21.561 8.071   44.780 1.00 18.43  ? 610 ARG C CG  1 
ATOM   8472  C CD  . ARG C 1 408 ? -22.216 9.321   44.237 1.00 20.56  ? 610 ARG C CD  1 
ATOM   8473  N NE  . ARG C 1 408 ? -23.507 9.008   43.633 1.00 23.46  ? 610 ARG C NE  1 
ATOM   8474  C CZ  . ARG C 1 408 ? -23.662 8.549   42.397 1.00 24.74  ? 610 ARG C CZ  1 
ATOM   8475  N NH1 . ARG C 1 408 ? -22.606 8.351   41.624 1.00 25.51  ? 610 ARG C NH1 1 
ATOM   8476  N NH2 . ARG C 1 408 ? -24.873 8.286   41.932 1.00 25.75  ? 610 ARG C NH2 1 
ATOM   8477  N N   . ASP C 1 409 ? -19.427 6.278   46.294 1.00 19.97  ? 611 ASP C N   1 
ATOM   8478  C CA  . ASP C 1 409 ? -18.073 6.385   46.809 1.00 20.41  ? 611 ASP C CA  1 
ATOM   8479  C C   . ASP C 1 409 ? -17.731 7.839   47.121 1.00 20.16  ? 611 ASP C C   1 
ATOM   8480  O O   . ASP C 1 409 ? -18.363 8.771   46.619 1.00 19.96  ? 611 ASP C O   1 
ATOM   8481  C CB  . ASP C 1 409 ? -17.088 5.811   45.793 1.00 18.75  ? 611 ASP C CB  1 
ATOM   8482  C CG  . ASP C 1 409 ? -15.713 5.609   46.365 1.00 21.09  ? 611 ASP C CG  1 
ATOM   8483  O OD1 . ASP C 1 409 ? -15.550 5.783   47.587 1.00 23.64  ? 611 ASP C OD1 1 
ATOM   8484  O OD2 . ASP C 1 409 ? -14.794 5.282   45.590 1.00 20.13  ? 611 ASP C OD2 1 
ATOM   8485  N N   . VAL C 1 410 ? -16.720 8.029   47.961 1.00 18.78  ? 612 VAL C N   1 
ATOM   8486  C CA  . VAL C 1 410 ? -16.236 9.355   48.321 1.00 17.40  ? 612 VAL C CA  1 
ATOM   8487  C C   . VAL C 1 410 ? -14.938 9.604   47.567 1.00 16.23  ? 612 VAL C C   1 
ATOM   8488  O O   . VAL C 1 410 ? -14.175 8.669   47.299 1.00 15.47  ? 612 VAL C O   1 
ATOM   8489  C CB  . VAL C 1 410 ? -16.039 9.496   49.838 1.00 14.82  ? 612 VAL C CB  1 
ATOM   8490  C CG1 . VAL C 1 410 ? -17.364 9.339   50.556 1.00 14.18  ? 612 VAL C CG1 1 
ATOM   8491  C CG2 . VAL C 1 410 ? -15.045 8.487   50.349 1.00 17.63  ? 612 VAL C CG2 1 
ATOM   8492  N N   . TYR C 1 411 ? -14.693 10.858  47.210 1.00 14.49  ? 613 TYR C N   1 
ATOM   8493  C CA  . TYR C 1 411 ? -13.540 11.195  46.396 1.00 14.11  ? 613 TYR C CA  1 
ATOM   8494  C C   . TYR C 1 411 ? -12.631 12.175  47.123 1.00 13.78  ? 613 TYR C C   1 
ATOM   8495  O O   . TYR C 1 411 ? -13.047 12.904  48.026 1.00 15.14  ? 613 TYR C O   1 
ATOM   8496  C CB  . TYR C 1 411 ? -13.986 11.786  45.065 1.00 10.20  ? 613 TYR C CB  1 
ATOM   8497  C CG  . TYR C 1 411 ? -14.713 10.794  44.210 1.00 13.70  ? 613 TYR C CG  1 
ATOM   8498  C CD1 . TYR C 1 411 ? -14.027 10.001  43.309 1.00 15.10  ? 613 TYR C CD1 1 
ATOM   8499  C CD2 . TYR C 1 411 ? -16.082 10.623  44.327 1.00 14.77  ? 613 TYR C CD2 1 
ATOM   8500  C CE1 . TYR C 1 411 ? -14.683 9.084   42.534 1.00 17.16  ? 613 TYR C CE1 1 
ATOM   8501  C CE2 . TYR C 1 411 ? -16.747 9.706   43.557 1.00 18.27  ? 613 TYR C CE2 1 
ATOM   8502  C CZ  . TYR C 1 411 ? -16.043 8.939   42.662 1.00 18.75  ? 613 TYR C CZ  1 
ATOM   8503  O OH  . TYR C 1 411 ? -16.705 8.021   41.888 1.00 20.71  ? 613 TYR C OH  1 
ATOM   8504  N N   . LEU C 1 412 ? -11.363 12.180  46.715 1.00 14.22  ? 614 LEU C N   1 
ATOM   8505  C CA  . LEU C 1 412 ? -10.426 13.167  47.232 1.00 13.68  ? 614 LEU C CA  1 
ATOM   8506  C C   . LEU C 1 412 ? -10.950 14.576  46.997 1.00 14.77  ? 614 LEU C C   1 
ATOM   8507  O O   . LEU C 1 412 ? -10.807 15.452  47.856 1.00 16.06  ? 614 LEU C O   1 
ATOM   8508  C CB  . LEU C 1 412 ? -9.054  12.962  46.588 1.00 16.19  ? 614 LEU C CB  1 
ATOM   8509  C CG  . LEU C 1 412 ? -7.834  13.769  47.038 1.00 15.93  ? 614 LEU C CG  1 
ATOM   8510  C CD1 . LEU C 1 412 ? -6.612  12.895  47.022 1.00 14.45  ? 614 LEU C CD1 1 
ATOM   8511  C CD2 . LEU C 1 412 ? -7.607  14.920  46.095 1.00 16.09  ? 614 LEU C CD2 1 
ATOM   8512  N N   . GLN C 1 413 ? -11.586 14.806  45.847 1.00 17.55  ? 615 GLN C N   1 
ATOM   8513  C CA  . GLN C 1 413 ? -12.146 16.121  45.552 1.00 17.40  ? 615 GLN C CA  1 
ATOM   8514  C C   . GLN C 1 413 ? -13.512 16.320  46.202 1.00 16.97  ? 615 GLN C C   1 
ATOM   8515  O O   . GLN C 1 413 ? -13.857 17.438  46.595 1.00 17.56  ? 615 GLN C O   1 
ATOM   8516  C CB  . GLN C 1 413 ? -12.255 16.315  44.043 1.00 12.20  ? 615 GLN C CB  1 
ATOM   8517  C CG  . GLN C 1 413 ? -10.941 16.282  43.304 1.00 17.60  ? 615 GLN C CG  1 
ATOM   8518  C CD  . GLN C 1 413 ? -10.499 14.874  42.990 1.00 20.49  ? 615 GLN C CD  1 
ATOM   8519  O OE1 . GLN C 1 413 ? -11.174 13.913  43.344 1.00 19.24  ? 615 GLN C OE1 1 
ATOM   8520  N NE2 . GLN C 1 413 ? -9.364  14.743  42.323 1.00 23.08  ? 615 GLN C NE2 1 
ATOM   8521  N N   . GLY C 1 414 ? -14.302 15.254  46.319 1.00 17.72  ? 616 GLY C N   1 
ATOM   8522  C CA  . GLY C 1 414 ? -15.707 15.362  46.641 1.00 16.08  ? 616 GLY C CA  1 
ATOM   8523  C C   . GLY C 1 414 ? -16.019 15.754  48.072 1.00 15.04  ? 616 GLY C C   1 
ATOM   8524  O O   . GLY C 1 414 ? -15.127 15.962  48.896 1.00 14.78  ? 616 GLY C O   1 
ATOM   8525  N N   . PRO C 1 415 ? -17.311 15.852  48.391 1.00 15.30  ? 617 PRO C N   1 
ATOM   8526  C CA  . PRO C 1 415 ? -17.716 16.361  49.707 1.00 15.49  ? 617 PRO C CA  1 
ATOM   8527  C C   . PRO C 1 415 ? -17.514 15.334  50.812 1.00 15.86  ? 617 PRO C C   1 
ATOM   8528  O O   . PRO C 1 415 ? -17.473 14.129  50.566 1.00 15.90  ? 617 PRO C O   1 
ATOM   8529  C CB  . PRO C 1 415 ? -19.200 16.681  49.511 1.00 14.78  ? 617 PRO C CB  1 
ATOM   8530  C CG  . PRO C 1 415 ? -19.631 15.733  48.454 1.00 15.50  ? 617 PRO C CG  1 
ATOM   8531  C CD  . PRO C 1 415 ? -18.470 15.605  47.519 1.00 14.11  ? 617 PRO C CD  1 
ATOM   8532  N N   . ILE C 1 416 ? -17.418 15.827  52.047 1.00 19.76  ? 618 ILE C N   1 
ATOM   8533  C CA  . ILE C 1 416 ? -17.196 14.945  53.191 1.00 17.99  ? 618 ILE C CA  1 
ATOM   8534  C C   . ILE C 1 416 ? -18.519 14.558  53.840 1.00 18.82  ? 618 ILE C C   1 
ATOM   8535  O O   . ILE C 1 416 ? -18.908 13.386  53.840 1.00 19.29  ? 618 ILE C O   1 
ATOM   8536  C CB  . ILE C 1 416 ? -16.252 15.601  54.214 1.00 20.31  ? 618 ILE C CB  1 
ATOM   8537  C CG1 . ILE C 1 416 ? -14.881 15.852  53.602 1.00 19.55  ? 618 ILE C CG1 1 
ATOM   8538  C CG2 . ILE C 1 416 ? -16.081 14.698  55.417 1.00 16.78  ? 618 ILE C CG2 1 
ATOM   8539  C CD1 . ILE C 1 416 ? -13.988 16.674  54.476 1.00 18.11  ? 618 ILE C CD1 1 
ATOM   8540  N N   . TRP C 1 417 ? -19.221 15.527  54.418 1.00 23.29  ? 619 TRP C N   1 
ATOM   8541  C CA  . TRP C 1 417 ? -20.447 15.259  55.150 1.00 23.55  ? 619 TRP C CA  1 
ATOM   8542  C C   . TRP C 1 417 ? -21.591 16.064  54.556 1.00 24.12  ? 619 TRP C C   1 
ATOM   8543  O O   . TRP C 1 417 ? -21.388 17.004  53.783 1.00 23.66  ? 619 TRP C O   1 
ATOM   8544  C CB  . TRP C 1 417 ? -20.326 15.609  56.641 1.00 23.95  ? 619 TRP C CB  1 
ATOM   8545  C CG  . TRP C 1 417 ? -20.115 17.067  56.889 1.00 25.23  ? 619 TRP C CG  1 
ATOM   8546  C CD1 . TRP C 1 417 ? -21.079 18.026  56.998 1.00 26.54  ? 619 TRP C CD1 1 
ATOM   8547  C CD2 . TRP C 1 417 ? -18.868 17.731  57.099 1.00 25.25  ? 619 TRP C CD2 1 
ATOM   8548  N NE1 . TRP C 1 417 ? -20.508 19.249  57.232 1.00 27.23  ? 619 TRP C NE1 1 
ATOM   8549  C CE2 . TRP C 1 417 ? -19.150 19.094  57.300 1.00 26.33  ? 619 TRP C CE2 1 
ATOM   8550  C CE3 . TRP C 1 417 ? -17.538 17.309  57.124 1.00 23.90  ? 619 TRP C CE3 1 
ATOM   8551  C CZ2 . TRP C 1 417 ? -18.153 20.034  57.524 1.00 26.84  ? 619 TRP C CZ2 1 
ATOM   8552  C CZ3 . TRP C 1 417 ? -16.552 18.243  57.343 1.00 25.37  ? 619 TRP C CZ3 1 
ATOM   8553  C CH2 . TRP C 1 417 ? -16.863 19.587  57.540 1.00 26.91  ? 619 TRP C CH2 1 
ATOM   8554  N N   . ALA C 1 418 ? -22.806 15.676  54.930 1.00 25.59  ? 620 ALA C N   1 
ATOM   8555  C CA  . ALA C 1 418 ? -23.997 16.463  54.663 1.00 26.77  ? 620 ALA C CA  1 
ATOM   8556  C C   . ALA C 1 418 ? -24.815 16.547  55.939 1.00 27.75  ? 620 ALA C C   1 
ATOM   8557  O O   . ALA C 1 418 ? -24.630 15.760  56.869 1.00 27.61  ? 620 ALA C O   1 
ATOM   8558  C CB  . ALA C 1 418 ? -24.841 15.860  53.539 1.00 24.61  ? 620 ALA C CB  1 
ATOM   8559  N N   . LYS C 1 419 ? -25.720 17.516  55.983 1.00 25.86  ? 621 LYS C N   1 
ATOM   8560  C CA  . LYS C 1 419 ? -26.668 17.635  57.080 1.00 26.44  ? 621 LYS C CA  1 
ATOM   8561  C C   . LYS C 1 419 ? -27.941 16.894  56.709 1.00 27.30  ? 621 LYS C C   1 
ATOM   8562  O O   . LYS C 1 419 ? -28.617 17.262  55.743 1.00 27.33  ? 621 LYS C O   1 
ATOM   8563  C CB  . LYS C 1 419 ? -26.990 19.091  57.398 1.00 26.74  ? 621 LYS C CB  1 
ATOM   8564  C CG  . LYS C 1 419 ? -27.931 19.237  58.574 1.00 28.11  ? 621 LYS C CG  1 
ATOM   8565  C CD  . LYS C 1 419 ? -28.142 20.681  58.963 1.00 30.15  ? 621 LYS C CD  1 
ATOM   8566  C CE  . LYS C 1 419 ? -29.104 20.781  60.129 1.00 33.06  ? 621 LYS C CE  1 
ATOM   8567  N NZ  . LYS C 1 419 ? -30.482 20.391  59.738 1.00 35.75  ? 621 LYS C NZ  1 
ATOM   8568  N N   . ILE C 1 420 ? -28.255 15.851  57.468 1.00 25.97  ? 622 ILE C N   1 
ATOM   8569  C CA  . ILE C 1 420 ? -29.549 15.183  57.313 1.00 26.48  ? 622 ILE C CA  1 
ATOM   8570  C C   . ILE C 1 420 ? -30.653 16.208  57.522 1.00 28.40  ? 622 ILE C C   1 
ATOM   8571  O O   . ILE C 1 420 ? -30.682 16.879  58.572 1.00 29.22  ? 622 ILE C O   1 
ATOM   8572  C CB  . ILE C 1 420 ? -29.682 14.029  58.317 1.00 28.97  ? 622 ILE C CB  1 
ATOM   8573  C CG1 . ILE C 1 420 ? -28.645 12.945  58.037 1.00 27.80  ? 622 ILE C CG1 1 
ATOM   8574  C CG2 . ILE C 1 420 ? -31.076 13.442  58.266 1.00 28.96  ? 622 ILE C CG2 1 
ATOM   8575  C CD1 . ILE C 1 420 ? -28.539 11.930  59.141 1.00 26.59  ? 622 ILE C CD1 1 
ATOM   8576  N N   . PRO C 1 421 ? -31.568 16.389  56.574 1.00 25.75  ? 623 PRO C N   1 
ATOM   8577  C CA  . PRO C 1 421 ? -32.643 17.367  56.768 1.00 26.68  ? 623 PRO C CA  1 
ATOM   8578  C C   . PRO C 1 421 ? -33.483 17.009  57.983 1.00 28.70  ? 623 PRO C C   1 
ATOM   8579  O O   . PRO C 1 421 ? -33.457 15.876  58.467 1.00 29.35  ? 623 PRO C O   1 
ATOM   8580  C CB  . PRO C 1 421 ? -33.449 17.264  55.469 1.00 25.50  ? 623 PRO C CB  1 
ATOM   8581  C CG  . PRO C 1 421 ? -32.474 16.755  54.471 1.00 25.46  ? 623 PRO C CG  1 
ATOM   8582  C CD  . PRO C 1 421 ? -31.596 15.805  55.224 1.00 24.97  ? 623 PRO C CD  1 
ATOM   8583  N N   . HIS C 1 422 ? -34.229 17.989  58.480 1.00 29.80  ? 624 HIS C N   1 
ATOM   8584  C CA  . HIS C 1 422 ? -35.016 17.787  59.689 1.00 31.24  ? 624 HIS C CA  1 
ATOM   8585  C C   . HIS C 1 422 ? -36.460 17.517  59.288 1.00 29.91  ? 624 HIS C C   1 
ATOM   8586  O O   . HIS C 1 422 ? -37.182 18.431  58.881 1.00 29.31  ? 624 HIS C O   1 
ATOM   8587  C CB  . HIS C 1 422 ? -34.903 19.018  60.582 1.00 30.72  ? 624 HIS C CB  1 
ATOM   8588  C CG  . HIS C 1 422 ? -35.557 18.866  61.919 1.00 35.79  ? 624 HIS C CG  1 
ATOM   8589  N ND1 . HIS C 1 422 ? -35.148 17.931  62.844 1.00 38.70  ? 624 HIS C ND1 1 
ATOM   8590  C CD2 . HIS C 1 422 ? -36.582 19.539  62.491 1.00 38.01  ? 624 HIS C CD2 1 
ATOM   8591  C CE1 . HIS C 1 422 ? -35.897 18.030  63.927 1.00 40.25  ? 624 HIS C CE1 1 
ATOM   8592  N NE2 . HIS C 1 422 ? -36.775 18.998  63.738 1.00 40.57  ? 624 HIS C NE2 1 
ATOM   8593  N N   . THR C 1 423 ? -36.883 16.262  59.414 1.00 32.72  ? 625 THR C N   1 
ATOM   8594  C CA  . THR C 1 423 ? -38.164 15.806  58.895 1.00 32.86  ? 625 THR C CA  1 
ATOM   8595  C C   . THR C 1 423 ? -38.738 14.758  59.838 1.00 33.02  ? 625 THR C C   1 
ATOM   8596  O O   . THR C 1 423 ? -38.059 14.271  60.744 1.00 32.77  ? 625 THR C O   1 
ATOM   8597  C CB  . THR C 1 423 ? -38.036 15.232  57.476 1.00 30.32  ? 625 THR C CB  1 
ATOM   8598  O OG1 . THR C 1 423 ? -37.053 14.188  57.463 1.00 29.83  ? 625 THR C OG1 1 
ATOM   8599  C CG2 . THR C 1 423 ? -37.658 16.313  56.470 1.00 29.29  ? 625 THR C CG2 1 
ATOM   8600  N N   . ASP C 1 424 ? -40.014 14.428  59.623 1.00 31.74  ? 626 ASP C N   1 
ATOM   8601  C CA  . ASP C 1 424 ? -40.647 13.379  60.418 1.00 32.12  ? 626 ASP C CA  1 
ATOM   8602  C C   . ASP C 1 424 ? -39.962 12.037  60.206 1.00 31.07  ? 626 ASP C C   1 
ATOM   8603  O O   . ASP C 1 424 ? -39.737 11.286  61.161 1.00 32.01  ? 626 ASP C O   1 
ATOM   8604  C CB  . ASP C 1 424 ? -42.135 13.280  60.084 1.00 34.84  ? 626 ASP C CB  1 
ATOM   8605  C CG  . ASP C 1 424 ? -42.931 14.432  60.647 1.00 38.75  ? 626 ASP C CG  1 
ATOM   8606  O OD1 . ASP C 1 424 ? -42.404 15.127  61.537 1.00 42.58  ? 626 ASP C OD1 1 
ATOM   8607  O OD2 . ASP C 1 424 ? -44.080 14.640  60.207 1.00 40.91  ? 626 ASP C OD2 1 
ATOM   8608  N N   . GLY C 1 425 ? -39.626 11.713  58.963 1.00 30.19  ? 627 GLY C N   1 
ATOM   8609  C CA  . GLY C 1 425 ? -38.947 10.462  58.697 1.00 27.69  ? 627 GLY C CA  1 
ATOM   8610  C C   . GLY C 1 425 ? -38.115 10.516  57.437 1.00 27.01  ? 627 GLY C C   1 
ATOM   8611  O O   . GLY C 1 425 ? -38.393 11.279  56.507 1.00 27.12  ? 627 GLY C O   1 
ATOM   8612  N N   . ASN C 1 426 ? -37.088 9.674   57.421 1.00 26.38  ? 628 ASN C N   1 
ATOM   8613  C CA  . ASN C 1 426 ? -36.224 9.507   56.266 1.00 26.00  ? 628 ASN C CA  1 
ATOM   8614  C C   . ASN C 1 426 ? -35.792 8.053   56.207 1.00 25.41  ? 628 ASN C C   1 
ATOM   8615  O O   . ASN C 1 426 ? -35.943 7.303   57.174 1.00 24.75  ? 628 ASN C O   1 
ATOM   8616  C CB  . ASN C 1 426 ? -35.014 10.449  56.319 1.00 25.93  ? 628 ASN C CB  1 
ATOM   8617  C CG  . ASN C 1 426 ? -34.155 10.251  57.560 1.00 25.33  ? 628 ASN C CG  1 
ATOM   8618  O OD1 . ASN C 1 426 ? -34.009 9.143   58.070 1.00 23.66  ? 628 ASN C OD1 1 
ATOM   8619  N ND2 . ASN C 1 426 ? -33.584 11.340  58.054 1.00 26.24  ? 628 ASN C ND2 1 
ATOM   8620  N N   . PHE C 1 427 ? -35.257 7.656   55.060 1.00 25.72  ? 629 PHE C N   1 
ATOM   8621  C CA  . PHE C 1 427 ? -34.735 6.309   54.900 1.00 25.31  ? 629 PHE C CA  1 
ATOM   8622  C C   . PHE C 1 427 ? -33.315 6.373   54.373 1.00 26.81  ? 629 PHE C C   1 
ATOM   8623  O O   . PHE C 1 427 ? -33.054 7.027   53.359 1.00 26.79  ? 629 PHE C O   1 
ATOM   8624  C CB  . PHE C 1 427 ? -35.589 5.470   53.959 1.00 23.51  ? 629 PHE C CB  1 
ATOM   8625  C CG  . PHE C 1 427 ? -35.037 4.098   53.726 1.00 23.94  ? 629 PHE C CG  1 
ATOM   8626  C CD1 . PHE C 1 427 ? -35.206 3.105   54.672 1.00 22.32  ? 629 PHE C CD1 1 
ATOM   8627  C CD2 . PHE C 1 427 ? -34.341 3.801   52.571 1.00 23.63  ? 629 PHE C CD2 1 
ATOM   8628  C CE1 . PHE C 1 427 ? -34.695 1.847   54.470 1.00 22.24  ? 629 PHE C CE1 1 
ATOM   8629  C CE2 . PHE C 1 427 ? -33.832 2.542   52.365 1.00 23.72  ? 629 PHE C CE2 1 
ATOM   8630  C CZ  . PHE C 1 427 ? -34.011 1.565   53.317 1.00 23.16  ? 629 PHE C CZ  1 
ATOM   8631  N N   . HIS C 1 428 ? -32.416 5.673   55.055 1.00 25.61  ? 630 HIS C N   1 
ATOM   8632  C CA  . HIS C 1 428 ? -31.009 5.566   54.701 1.00 26.72  ? 630 HIS C CA  1 
ATOM   8633  C C   . HIS C 1 428 ? -30.455 6.969   54.485 1.00 27.25  ? 630 HIS C C   1 
ATOM   8634  O O   . HIS C 1 428 ? -30.201 7.380   53.346 1.00 27.85  ? 630 HIS C O   1 
ATOM   8635  C CB  . HIS C 1 428 ? -30.830 4.688   53.464 1.00 23.37  ? 630 HIS C CB  1 
ATOM   8636  C CG  . HIS C 1 428 ? -29.420 4.245   53.245 1.00 24.81  ? 630 HIS C CG  1 
ATOM   8637  N ND1 . HIS C 1 428 ? -28.746 3.459   54.154 1.00 25.40  ? 630 HIS C ND1 1 
ATOM   8638  C CD2 . HIS C 1 428 ? -28.558 4.469   52.228 1.00 25.07  ? 630 HIS C CD2 1 
ATOM   8639  C CE1 . HIS C 1 428 ? -27.528 3.218   53.705 1.00 25.89  ? 630 HIS C CE1 1 
ATOM   8640  N NE2 . HIS C 1 428 ? -27.389 3.819   52.538 1.00 25.69  ? 630 HIS C NE2 1 
ATOM   8641  N N   . PRO C 1 429 ? -30.267 7.723   55.559 1.00 27.90  ? 631 PRO C N   1 
ATOM   8642  C CA  . PRO C 1 429 ? -29.956 9.155   55.447 1.00 27.52  ? 631 PRO C CA  1 
ATOM   8643  C C   . PRO C 1 429 ? -28.677 9.490   54.695 1.00 27.50  ? 631 PRO C C   1 
ATOM   8644  O O   . PRO C 1 429 ? -28.415 10.671  54.453 1.00 28.83  ? 631 PRO C O   1 
ATOM   8645  C CB  . PRO C 1 429 ? -29.872 9.597   56.911 1.00 31.57  ? 631 PRO C CB  1 
ATOM   8646  C CG  . PRO C 1 429 ? -29.517 8.366   57.656 1.00 31.00  ? 631 PRO C CG  1 
ATOM   8647  C CD  . PRO C 1 429 ? -30.246 7.264   56.957 1.00 31.06  ? 631 PRO C CD  1 
ATOM   8648  N N   . SER C 1 430 ? -27.855 8.493   54.386 1.00 24.94  ? 632 SER C N   1 
ATOM   8649  C CA  . SER C 1 430 ? -26.582 8.728   53.720 1.00 24.32  ? 632 SER C CA  1 
ATOM   8650  C C   . SER C 1 430 ? -26.768 9.644   52.508 1.00 23.62  ? 632 SER C C   1 
ATOM   8651  O O   . SER C 1 430 ? -27.655 9.395   51.679 1.00 23.68  ? 632 SER C O   1 
ATOM   8652  C CB  . SER C 1 430 ? -25.967 7.398   53.282 1.00 20.66  ? 632 SER C CB  1 
ATOM   8653  O OG  . SER C 1 430 ? -24.748 7.595   52.592 1.00 25.01  ? 632 SER C OG  1 
ATOM   8654  N N   . PRO C 1 431 ? -25.967 10.702  52.373 1.00 21.85  ? 633 PRO C N   1 
ATOM   8655  C CA  . PRO C 1 431 ? -26.178 11.663  51.286 1.00 21.56  ? 633 PRO C CA  1 
ATOM   8656  C C   . PRO C 1 431 ? -25.898 11.063  49.919 1.00 21.62  ? 633 PRO C C   1 
ATOM   8657  O O   . PRO C 1 431 ? -25.081 10.153  49.765 1.00 22.04  ? 633 PRO C O   1 
ATOM   8658  C CB  . PRO C 1 431 ? -25.184 12.784  51.613 1.00 19.99  ? 633 PRO C CB  1 
ATOM   8659  C CG  . PRO C 1 431 ? -24.132 12.125  52.419 1.00 21.16  ? 633 PRO C CG  1 
ATOM   8660  C CD  . PRO C 1 431 ? -24.835 11.087  53.231 1.00 20.23  ? 633 PRO C CD  1 
ATOM   8661  N N   . LEU C 1 432 ? -26.585 11.605  48.912 1.00 19.67  ? 634 LEU C N   1 
ATOM   8662  C CA  . LEU C 1 432 ? -26.549 11.014  47.581 1.00 19.67  ? 634 LEU C CA  1 
ATOM   8663  C C   . LEU C 1 432 ? -25.317 11.407  46.778 1.00 20.94  ? 634 LEU C C   1 
ATOM   8664  O O   . LEU C 1 432 ? -25.007 10.736  45.790 1.00 20.97  ? 634 LEU C O   1 
ATOM   8665  C CB  . LEU C 1 432 ? -27.814 11.381  46.811 1.00 23.46  ? 634 LEU C CB  1 
ATOM   8666  C CG  . LEU C 1 432 ? -29.078 10.721  47.357 1.00 21.53  ? 634 LEU C CG  1 
ATOM   8667  C CD1 . LEU C 1 432 ? -30.312 11.217  46.638 1.00 20.72  ? 634 LEU C CD1 1 
ATOM   8668  C CD2 . LEU C 1 432 ? -28.956 9.216   47.230 1.00 18.76  ? 634 LEU C CD2 1 
ATOM   8669  N N   . MET C 1 433 ? -24.605 12.462  47.165 1.00 19.03  ? 635 MET C N   1 
ATOM   8670  C CA  . MET C 1 433 ? -23.333 12.753  46.514 1.00 19.82  ? 635 MET C CA  1 
ATOM   8671  C C   . MET C 1 433 ? -22.159 12.069  47.197 1.00 19.98  ? 635 MET C C   1 
ATOM   8672  O O   . MET C 1 433 ? -21.016 12.271  46.779 1.00 19.49  ? 635 MET C O   1 
ATOM   8673  C CB  . MET C 1 433 ? -23.084 14.262  46.450 1.00 17.79  ? 635 MET C CB  1 
ATOM   8674  C CG  . MET C 1 433 ? -24.012 15.007  45.511 1.00 20.19  ? 635 MET C CG  1 
ATOM   8675  S SD  . MET C 1 433 ? -23.590 16.747  45.324 1.00 25.91  ? 635 MET C SD  1 
ATOM   8676  C CE  . MET C 1 433 ? -24.173 17.430  46.868 1.00 24.99  ? 635 MET C CE  1 
ATOM   8677  N N   . GLY C 1 434 ? -22.409 11.267  48.218 1.00 19.20  ? 636 GLY C N   1 
ATOM   8678  C CA  . GLY C 1 434 ? -21.369 10.581  48.951 1.00 18.25  ? 636 GLY C CA  1 
ATOM   8679  C C   . GLY C 1 434 ? -21.058 11.275  50.266 1.00 18.03  ? 636 GLY C C   1 
ATOM   8680  O O   . GLY C 1 434 ? -21.273 12.477  50.441 1.00 19.27  ? 636 GLY C O   1 
ATOM   8681  N N   . GLY C 1 435 ? -20.524 10.499  51.196 1.00 21.07  ? 637 GLY C N   1 
ATOM   8682  C CA  . GLY C 1 435 ? -20.169 11.017  52.496 1.00 19.28  ? 637 GLY C CA  1 
ATOM   8683  C C   . GLY C 1 435 ? -21.109 10.600  53.608 1.00 17.84  ? 637 GLY C C   1 
ATOM   8684  O O   . GLY C 1 435 ? -21.960 9.721   53.464 1.00 17.45  ? 637 GLY C O   1 
ATOM   8685  N N   . PHE C 1 436 ? -20.931 11.254  54.752 1.00 22.82  ? 638 PHE C N   1 
ATOM   8686  C CA  . PHE C 1 436 ? -21.556 10.860  56.007 1.00 22.60  ? 638 PHE C CA  1 
ATOM   8687  C C   . PHE C 1 436 ? -22.737 11.772  56.304 1.00 24.27  ? 638 PHE C C   1 
ATOM   8688  O O   . PHE C 1 436 ? -22.563 12.983  56.469 1.00 26.20  ? 638 PHE C O   1 
ATOM   8689  C CB  . PHE C 1 436 ? -20.544 10.922  57.150 1.00 21.38  ? 638 PHE C CB  1 
ATOM   8690  C CG  . PHE C 1 436 ? -19.347 10.042  56.950 1.00 20.82  ? 638 PHE C CG  1 
ATOM   8691  C CD1 . PHE C 1 436 ? -19.388 8.704   57.289 1.00 20.20  ? 638 PHE C CD1 1 
ATOM   8692  C CD2 . PHE C 1 436 ? -18.178 10.557  56.426 1.00 20.48  ? 638 PHE C CD2 1 
ATOM   8693  C CE1 . PHE C 1 436 ? -18.286 7.901   57.107 1.00 20.61  ? 638 PHE C CE1 1 
ATOM   8694  C CE2 . PHE C 1 436 ? -17.073 9.755   56.242 1.00 20.74  ? 638 PHE C CE2 1 
ATOM   8695  C CZ  . PHE C 1 436 ? -17.128 8.427   56.581 1.00 20.33  ? 638 PHE C CZ  1 
ATOM   8696  N N   . GLY C 1 437 ? -23.932 11.192  56.374 1.00 24.88  ? 639 GLY C N   1 
ATOM   8697  C CA  . GLY C 1 437 ? -25.096 11.949  56.797 1.00 25.27  ? 639 GLY C CA  1 
ATOM   8698  C C   . GLY C 1 437 ? -25.079 12.187  58.298 1.00 26.35  ? 639 GLY C C   1 
ATOM   8699  O O   . GLY C 1 437 ? -24.791 11.291  59.089 1.00 26.38  ? 639 GLY C O   1 
ATOM   8700  N N   . MET C 1 438 ? -25.399 13.418  58.686 1.00 29.29  ? 640 MET C N   1 
ATOM   8701  C CA  . MET C 1 438 ? -25.396 13.805  60.088 1.00 29.90  ? 640 MET C CA  1 
ATOM   8702  C C   . MET C 1 438 ? -26.573 14.726  60.368 1.00 30.61  ? 640 MET C C   1 
ATOM   8703  O O   . MET C 1 438 ? -26.837 15.652  59.598 1.00 30.64  ? 640 MET C O   1 
ATOM   8704  C CB  . MET C 1 438 ? -24.089 14.514  60.462 1.00 29.93  ? 640 MET C CB  1 
ATOM   8705  C CG  . MET C 1 438 ? -22.846 13.651  60.352 1.00 34.44  ? 640 MET C CG  1 
ATOM   8706  S SD  . MET C 1 438 ? -21.349 14.570  60.735 1.00 38.91  ? 640 MET C SD  1 
ATOM   8707  C CE  . MET C 1 438 ? -21.548 14.776  62.500 1.00 38.80  ? 640 MET C CE  1 
ATOM   8708  N N   . LYS C 1 439 ? -27.277 14.474  61.471 1.00 31.55  ? 641 LYS C N   1 
ATOM   8709  C CA  . LYS C 1 439 ? -28.305 15.408  61.912 1.00 33.49  ? 641 LYS C CA  1 
ATOM   8710  C C   . LYS C 1 439 ? -27.721 16.602  62.648 1.00 33.44  ? 641 LYS C C   1 
ATOM   8711  O O   . LYS C 1 439 ? -28.412 17.613  62.815 1.00 34.16  ? 641 LYS C O   1 
ATOM   8712  C CB  . LYS C 1 439 ? -29.332 14.713  62.805 1.00 34.98  ? 641 LYS C CB  1 
ATOM   8713  C CG  . LYS C 1 439 ? -30.251 13.760  62.065 1.00 40.88  ? 641 LYS C CG  1 
ATOM   8714  C CD  . LYS C 1 439 ? -31.427 13.336  62.930 1.00 47.30  ? 641 LYS C CD  1 
ATOM   8715  C CE  . LYS C 1 439 ? -30.978 12.530  64.135 1.00 49.67  ? 641 LYS C CE  1 
ATOM   8716  N NZ  . LYS C 1 439 ? -32.142 12.027  64.917 1.00 50.42  ? 641 LYS C NZ  1 
ATOM   8717  N N   . HIS C 1 440 ? -26.474 16.506  63.093 1.00 33.66  ? 642 HIS C N   1 
ATOM   8718  C CA  . HIS C 1 440 ? -25.755 17.620  63.705 1.00 33.50  ? 642 HIS C CA  1 
ATOM   8719  C C   . HIS C 1 440 ? -24.361 17.642  63.100 1.00 31.85  ? 642 HIS C C   1 
ATOM   8720  O O   . HIS C 1 440 ? -23.401 17.145  63.703 1.00 31.96  ? 642 HIS C O   1 
ATOM   8721  C CB  . HIS C 1 440 ? -25.703 17.486  65.226 1.00 30.50  ? 642 HIS C CB  1 
ATOM   8722  C CG  . HIS C 1 440 ? -27.051 17.422  65.873 1.00 35.61  ? 642 HIS C CG  1 
ATOM   8723  N ND1 . HIS C 1 440 ? -27.911 18.497  65.910 1.00 36.87  ? 642 HIS C ND1 1 
ATOM   8724  C CD2 . HIS C 1 440 ? -27.683 16.412  66.515 1.00 36.70  ? 642 HIS C CD2 1 
ATOM   8725  C CE1 . HIS C 1 440 ? -29.018 18.151  66.543 1.00 38.06  ? 642 HIS C CE1 1 
ATOM   8726  N NE2 . HIS C 1 440 ? -28.905 16.890  66.919 1.00 39.28  ? 642 HIS C NE2 1 
ATOM   8727  N N   . PRO C 1 441 ? -24.213 18.198  61.902 1.00 34.46  ? 643 PRO C N   1 
ATOM   8728  C CA  . PRO C 1 441 ? -22.903 18.241  61.253 1.00 32.87  ? 643 PRO C CA  1 
ATOM   8729  C C   . PRO C 1 441 ? -22.016 19.292  61.897 1.00 32.13  ? 643 PRO C C   1 
ATOM   8730  O O   . PRO C 1 441 ? -22.457 19.997  62.817 1.00 32.21  ? 643 PRO C O   1 
ATOM   8731  C CB  . PRO C 1 441 ? -23.252 18.614  59.807 1.00 32.73  ? 643 PRO C CB  1 
ATOM   8732  C CG  . PRO C 1 441 ? -24.499 19.386  59.934 1.00 32.55  ? 643 PRO C CG  1 
ATOM   8733  C CD  . PRO C 1 441 ? -25.272 18.735  61.034 1.00 32.51  ? 643 PRO C CD  1 
ATOM   8734  N N   . PRO C 1 442 ? -20.761 19.417  61.464 1.00 33.62  ? 644 PRO C N   1 
ATOM   8735  C CA  . PRO C 1 442 ? -19.903 20.481  61.984 1.00 33.11  ? 644 PRO C CA  1 
ATOM   8736  C C   . PRO C 1 442 ? -20.536 21.840  61.769 1.00 33.40  ? 644 PRO C C   1 
ATOM   8737  O O   . PRO C 1 442 ? -21.060 22.128  60.683 1.00 33.13  ? 644 PRO C O   1 
ATOM   8738  C CB  . PRO C 1 442 ? -18.618 20.330  61.162 1.00 30.13  ? 644 PRO C CB  1 
ATOM   8739  C CG  . PRO C 1 442 ? -18.574 18.915  60.839 1.00 30.48  ? 644 PRO C CG  1 
ATOM   8740  C CD  . PRO C 1 442 ? -19.992 18.473  60.633 1.00 30.21  ? 644 PRO C CD  1 
ATOM   8741  N N   . PRO C 1 443 ? -20.508 22.701  62.777 1.00 34.21  ? 645 PRO C N   1 
ATOM   8742  C CA  . PRO C 1 443 ? -21.262 23.952  62.695 1.00 34.26  ? 645 PRO C CA  1 
ATOM   8743  C C   . PRO C 1 443 ? -20.621 24.935  61.731 1.00 34.75  ? 645 PRO C C   1 
ATOM   8744  O O   . PRO C 1 443 ? -19.403 24.973  61.545 1.00 34.68  ? 645 PRO C O   1 
ATOM   8745  C CB  . PRO C 1 443 ? -21.226 24.478  64.133 1.00 33.14  ? 645 PRO C CB  1 
ATOM   8746  C CG  . PRO C 1 443 ? -19.966 23.925  64.688 1.00 33.02  ? 645 PRO C CG  1 
ATOM   8747  C CD  . PRO C 1 443 ? -19.766 22.583  64.042 1.00 33.48  ? 645 PRO C CD  1 
ATOM   8748  N N   . GLN C 1 444 ? -21.478 25.731  61.100 1.00 34.80  ? 646 GLN C N   1 
ATOM   8749  C CA  . GLN C 1 444 ? -21.009 26.787  60.219 1.00 35.86  ? 646 GLN C CA  1 
ATOM   8750  C C   . GLN C 1 444 ? -20.229 27.827  61.008 1.00 35.63  ? 646 GLN C C   1 
ATOM   8751  O O   . GLN C 1 444 ? -20.509 28.083  62.181 1.00 35.75  ? 646 GLN C O   1 
ATOM   8752  C CB  . GLN C 1 444 ? -22.182 27.444  59.504 1.00 29.29  ? 646 GLN C CB  1 
ATOM   8753  C CG  . GLN C 1 444 ? -22.842 26.557  58.481 1.00 34.09  ? 646 GLN C CG  1 
ATOM   8754  C CD  . GLN C 1 444 ? -24.055 27.201  57.864 1.00 35.42  ? 646 GLN C CD  1 
ATOM   8755  O OE1 . GLN C 1 444 ? -24.732 28.012  58.492 1.00 36.47  ? 646 GLN C OE1 1 
ATOM   8756  N NE2 . GLN C 1 444 ? -24.321 26.868  56.616 1.00 35.53  ? 646 GLN C NE2 1 
ATOM   8757  N N   . ILE C 1 445 ? -19.244 28.427  60.352 1.00 33.86  ? 647 ILE C N   1 
ATOM   8758  C CA  . ILE C 1 445 ? -18.349 29.393  60.969 1.00 31.94  ? 647 ILE C CA  1 
ATOM   8759  C C   . ILE C 1 445 ? -18.529 30.693  60.207 1.00 32.00  ? 647 ILE C C   1 
ATOM   8760  O O   . ILE C 1 445 ? -18.131 30.790  59.041 1.00 33.13  ? 647 ILE C O   1 
ATOM   8761  C CB  . ILE C 1 445 ? -16.892 28.926  60.915 1.00 32.52  ? 647 ILE C CB  1 
ATOM   8762  C CG1 . ILE C 1 445 ? -16.738 27.575  61.602 1.00 31.47  ? 647 ILE C CG1 1 
ATOM   8763  C CG2 . ILE C 1 445 ? -15.996 29.932  61.591 1.00 30.25  ? 647 ILE C CG2 1 
ATOM   8764  C CD1 . ILE C 1 445 ? -15.437 26.906  61.275 1.00 31.03  ? 647 ILE C CD1 1 
ATOM   8765  N N   . LEU C 1 446 ? -19.111 31.694  60.855 1.00 35.46  ? 648 LEU C N   1 
ATOM   8766  C CA  . LEU C 1 446 ? -19.445 32.947  60.197 1.00 34.93  ? 648 LEU C CA  1 
ATOM   8767  C C   . LEU C 1 446 ? -18.513 34.055  60.667 1.00 34.87  ? 648 LEU C C   1 
ATOM   8768  O O   . LEU C 1 446 ? -18.308 34.250  61.867 1.00 36.80  ? 648 LEU C O   1 
ATOM   8769  C CB  . LEU C 1 446 ? -20.902 33.336  60.460 1.00 33.17  ? 648 LEU C CB  1 
ATOM   8770  C CG  . LEU C 1 446 ? -21.970 32.703  59.562 1.00 33.02  ? 648 LEU C CG  1 
ATOM   8771  C CD1 . LEU C 1 446 ? -21.679 33.000  58.105 1.00 33.48  ? 648 LEU C CD1 1 
ATOM   8772  C CD2 . LEU C 1 446 ? -22.078 31.212  59.783 1.00 32.91  ? 648 LEU C CD2 1 
ATOM   8773  N N   . ILE C 1 447 ? -17.952 34.779  59.702 1.00 34.09  ? 649 ILE C N   1 
ATOM   8774  C CA  . ILE C 1 447 ? -16.947 35.801  59.969 1.00 33.73  ? 649 ILE C CA  1 
ATOM   8775  C C   . ILE C 1 447 ? -17.227 37.000  59.074 1.00 34.30  ? 649 ILE C C   1 
ATOM   8776  O O   . ILE C 1 447 ? -17.686 36.848  57.939 1.00 34.99  ? 649 ILE C O   1 
ATOM   8777  C CB  . ILE C 1 447 ? -15.526 35.246  59.743 1.00 33.56  ? 649 ILE C CB  1 
ATOM   8778  C CG1 . ILE C 1 447 ? -14.471 36.278  60.128 1.00 33.15  ? 649 ILE C CG1 1 
ATOM   8779  C CG2 . ILE C 1 447 ? -15.347 34.815  58.303 1.00 32.88  ? 649 ILE C CG2 1 
ATOM   8780  C CD1 . ILE C 1 447 ? -13.072 35.732  60.144 1.00 33.32  ? 649 ILE C CD1 1 
ATOM   8781  N N   . LYS C 1 448 ? -16.959 38.198  59.591 1.00 35.77  ? 650 LYS C N   1 
ATOM   8782  C CA  . LYS C 1 448 ? -17.105 39.414  58.804 1.00 37.05  ? 650 LYS C CA  1 
ATOM   8783  C C   . LYS C 1 448 ? -16.161 40.473  59.348 1.00 38.33  ? 650 LYS C C   1 
ATOM   8784  O O   . LYS C 1 448 ? -15.643 40.358  60.462 1.00 38.00  ? 650 LYS C O   1 
ATOM   8785  C CB  . LYS C 1 448 ? -18.538 39.952  58.825 1.00 33.80  ? 650 LYS C CB  1 
ATOM   8786  C CG  . LYS C 1 448 ? -18.987 40.427  60.186 1.00 35.63  ? 650 LYS C CG  1 
ATOM   8787  C CD  . LYS C 1 448 ? -20.335 41.101  60.111 1.00 36.97  ? 650 LYS C CD  1 
ATOM   8788  C CE  . LYS C 1 448 ? -20.236 42.398  59.332 1.00 41.08  ? 650 LYS C CE  1 
ATOM   8789  N NZ  . LYS C 1 448 ? -21.534 43.110  59.257 1.00 40.19  ? 650 LYS C NZ  1 
ATOM   8790  N N   . ASN C 1 449 ? -15.949 41.512  58.546 1.00 38.94  ? 651 ASN C N   1 
ATOM   8791  C CA  . ASN C 1 449 ? -15.234 42.690  59.011 1.00 40.02  ? 651 ASN C CA  1 
ATOM   8792  C C   . ASN C 1 449 ? -16.218 43.649  59.665 1.00 40.88  ? 651 ASN C C   1 
ATOM   8793  O O   . ASN C 1 449 ? -17.313 43.877  59.143 1.00 41.78  ? 651 ASN C O   1 
ATOM   8794  C CB  . ASN C 1 449 ? -14.526 43.384  57.851 1.00 37.63  ? 651 ASN C CB  1 
ATOM   8795  C CG  . ASN C 1 449 ? -13.546 42.481  57.145 1.00 40.71  ? 651 ASN C CG  1 
ATOM   8796  O OD1 . ASN C 1 449 ? -13.526 42.414  55.919 1.00 42.09  ? 651 ASN C OD1 1 
ATOM   8797  N ND2 . ASN C 1 449 ? -12.739 41.766  57.914 1.00 42.77  ? 651 ASN C ND2 1 
ATOM   8798  N N   . THR C 1 450 ? -15.833 44.206  60.803 1.00 44.17  ? 652 THR C N   1 
ATOM   8799  C CA  . THR C 1 450 ? -16.671 45.200  61.461 1.00 45.52  ? 652 THR C CA  1 
ATOM   8800  C C   . THR C 1 450 ? -16.656 46.493  60.654 1.00 44.06  ? 652 THR C C   1 
ATOM   8801  O O   . THR C 1 450 ? -15.577 46.979  60.296 1.00 42.88  ? 652 THR C O   1 
ATOM   8802  C CB  . THR C 1 450 ? -16.172 45.458  62.879 1.00 42.06  ? 652 THR C CB  1 
ATOM   8803  O OG1 . THR C 1 450 ? -16.228 44.245  63.639 1.00 49.62  ? 652 THR C OG1 1 
ATOM   8804  C CG2 . THR C 1 450 ? -17.018 46.518  63.565 1.00 41.85  ? 652 THR C CG2 1 
ATOM   8805  N N   . PRO C 1 451 ? -17.815 47.073  60.335 1.00 49.04  ? 653 PRO C N   1 
ATOM   8806  C CA  . PRO C 1 451 ? -17.816 48.321  59.566 1.00 48.79  ? 653 PRO C CA  1 
ATOM   8807  C C   . PRO C 1 451 ? -17.220 49.465  60.370 1.00 49.13  ? 653 PRO C C   1 
ATOM   8808  O O   . PRO C 1 451 ? -17.587 49.699  61.524 1.00 49.39  ? 653 PRO C O   1 
ATOM   8809  C CB  . PRO C 1 451 ? -19.301 48.553  59.271 1.00 47.30  ? 653 PRO C CB  1 
ATOM   8810  C CG  . PRO C 1 451 ? -20.004 47.874  60.386 1.00 46.34  ? 653 PRO C CG  1 
ATOM   8811  C CD  . PRO C 1 451 ? -19.177 46.660  60.713 1.00 47.06  ? 653 PRO C CD  1 
ATOM   8812  N N   . VAL C 1 452 ? -16.293 50.182  59.745 1.00 49.61  ? 654 VAL C N   1 
ATOM   8813  C CA  . VAL C 1 452 ? -15.564 51.247  60.425 1.00 49.60  ? 654 VAL C CA  1 
ATOM   8814  C C   . VAL C 1 452 ? -15.895 52.580  59.766 1.00 49.71  ? 654 VAL C C   1 
ATOM   8815  O O   . VAL C 1 452 ? -15.480 52.825  58.625 1.00 50.11  ? 654 VAL C O   1 
ATOM   8816  C CB  . VAL C 1 452 ? -14.053 50.980  60.407 1.00 50.51  ? 654 VAL C CB  1 
ATOM   8817  C CG1 . VAL C 1 452 ? -13.309 52.130  61.051 1.00 50.06  ? 654 VAL C CG1 1 
ATOM   8818  C CG2 . VAL C 1 452 ? -13.745 49.678  61.120 1.00 48.86  ? 654 VAL C CG2 1 
ATOM   8819  N N   . PRO C 1 453 ? -16.635 53.471  60.440 1.00 52.11  ? 655 PRO C N   1 
ATOM   8820  C CA  . PRO C 1 453 ? -16.999 54.777  59.881 1.00 52.68  ? 655 PRO C CA  1 
ATOM   8821  C C   . PRO C 1 453 ? -15.811 55.727  59.768 1.00 54.21  ? 655 PRO C C   1 
ATOM   8822  O O   . PRO C 1 453 ? -15.613 56.316  58.705 1.00 53.62  ? 655 PRO C O   1 
ATOM   8823  C CB  . PRO C 1 453 ? -18.028 55.306  60.883 1.00 53.43  ? 655 PRO C CB  1 
ATOM   8824  C CG  . PRO C 1 453 ? -17.671 54.644  62.163 1.00 53.71  ? 655 PRO C CG  1 
ATOM   8825  C CD  . PRO C 1 453 ? -17.197 53.273  61.787 1.00 53.30  ? 655 PRO C CD  1 
ATOM   8826  N N   . LEU C 1 465 ? -26.154 55.609  57.843 1.00 63.88  ? 667 LEU C N   1 
ATOM   8827  C CA  . LEU C 1 465 ? -24.766 55.863  57.475 1.00 64.07  ? 667 LEU C CA  1 
ATOM   8828  C C   . LEU C 1 465 ? -24.312 54.927  56.364 1.00 64.62  ? 667 LEU C C   1 
ATOM   8829  O O   . LEU C 1 465 ? -24.034 53.759  56.613 1.00 64.71  ? 667 LEU C O   1 
ATOM   8830  C CB  . LEU C 1 465 ? -23.852 55.705  58.689 1.00 60.36  ? 667 LEU C CB  1 
ATOM   8831  C CG  . LEU C 1 465 ? -24.067 56.704  59.823 1.00 59.71  ? 667 LEU C CG  1 
ATOM   8832  C CD1 . LEU C 1 465 ? -23.177 56.365  61.003 1.00 60.50  ? 667 LEU C CD1 1 
ATOM   8833  C CD2 . LEU C 1 465 ? -23.802 58.115  59.333 1.00 59.29  ? 667 LEU C CD2 1 
ATOM   8834  N N   . ASN C 1 466 ? -24.254 55.438  55.136 1.00 64.85  ? 668 ASN C N   1 
ATOM   8835  C CA  . ASN C 1 466 ? -23.875 54.641  53.979 1.00 66.33  ? 668 ASN C CA  1 
ATOM   8836  C C   . ASN C 1 466 ? -22.413 54.794  53.579 1.00 65.44  ? 668 ASN C C   1 
ATOM   8837  O O   . ASN C 1 466 ? -21.982 54.151  52.618 1.00 66.09  ? 668 ASN C O   1 
ATOM   8838  C CB  . ASN C 1 466 ? -24.781 54.977  52.787 1.00 64.65  ? 668 ASN C CB  1 
ATOM   8839  C CG  . ASN C 1 466 ? -24.725 56.444  52.392 1.00 70.01  ? 668 ASN C CG  1 
ATOM   8840  O OD1 . ASN C 1 466 ? -23.692 57.103  52.514 1.00 73.55  ? 668 ASN C OD1 1 
ATOM   8841  N ND2 . ASN C 1 466 ? -25.848 56.962  51.912 1.00 73.35  ? 668 ASN C ND2 1 
ATOM   8842  N N   . SER C 1 467 ? -21.643 55.628  54.275 1.00 66.05  ? 669 SER C N   1 
ATOM   8843  C CA  . SER C 1 467 ? -20.250 55.884  53.925 1.00 64.24  ? 669 SER C CA  1 
ATOM   8844  C C   . SER C 1 467 ? -19.347 55.230  54.960 1.00 63.01  ? 669 SER C C   1 
ATOM   8845  O O   . SER C 1 467 ? -19.440 55.538  56.153 1.00 61.87  ? 669 SER C O   1 
ATOM   8846  C CB  . SER C 1 467 ? -19.967 57.385  53.834 1.00 63.94  ? 669 SER C CB  1 
ATOM   8847  O OG  . SER C 1 467 ? -18.604 57.623  53.529 1.00 66.14  ? 669 SER C OG  1 
ATOM   8848  N N   . PHE C 1 468 ? -18.473 54.339  54.501 1.00 57.33  ? 670 PHE C N   1 
ATOM   8849  C CA  . PHE C 1 468 ? -17.582 53.591  55.370 1.00 56.23  ? 670 PHE C CA  1 
ATOM   8850  C C   . PHE C 1 468 ? -16.163 53.656  54.824 1.00 55.95  ? 670 PHE C C   1 
ATOM   8851  O O   . PHE C 1 468 ? -15.882 54.358  53.851 1.00 57.15  ? 670 PHE C O   1 
ATOM   8852  C CB  . PHE C 1 468 ? -18.035 52.136  55.500 1.00 55.02  ? 670 PHE C CB  1 
ATOM   8853  C CG  . PHE C 1 468 ? -19.397 51.982  56.112 1.00 56.04  ? 670 PHE C CG  1 
ATOM   8854  C CD1 . PHE C 1 468 ? -19.555 51.960  57.485 1.00 56.98  ? 670 PHE C CD1 1 
ATOM   8855  C CD2 . PHE C 1 468 ? -20.520 51.863  55.313 1.00 55.64  ? 670 PHE C CD2 1 
ATOM   8856  C CE1 . PHE C 1 468 ? -20.805 51.819  58.049 1.00 58.34  ? 670 PHE C CE1 1 
ATOM   8857  C CE2 . PHE C 1 468 ? -21.770 51.723  55.873 1.00 56.78  ? 670 PHE C CE2 1 
ATOM   8858  C CZ  . PHE C 1 468 ? -21.911 51.700  57.242 1.00 57.52  ? 670 PHE C CZ  1 
ATOM   8859  N N   . ILE C 1 469 ? -15.270 52.908  55.464 1.00 55.07  ? 671 ILE C N   1 
ATOM   8860  C CA  . ILE C 1 469 ? -13.856 52.921  55.105 1.00 54.59  ? 671 ILE C CA  1 
ATOM   8861  C C   . ILE C 1 469 ? -13.525 51.663  54.313 1.00 54.64  ? 671 ILE C C   1 
ATOM   8862  O O   . ILE C 1 469 ? -13.948 50.560  54.677 1.00 54.82  ? 671 ILE C O   1 
ATOM   8863  C CB  . ILE C 1 469 ? -12.983 53.035  56.364 1.00 52.96  ? 671 ILE C CB  1 
ATOM   8864  C CG1 . ILE C 1 469 ? -13.201 54.392  57.033 1.00 52.68  ? 671 ILE C CG1 1 
ATOM   8865  C CG2 . ILE C 1 469 ? -11.515 52.838  56.027 1.00 52.38  ? 671 ILE C CG2 1 
ATOM   8866  C CD1 . ILE C 1 469 ? -12.550 54.512  58.393 1.00 56.34  ? 671 ILE C CD1 1 
ATOM   8867  N N   . THR C 1 470 ? -12.768 51.824  53.226 1.00 57.21  ? 672 THR C N   1 
ATOM   8868  C CA  . THR C 1 470 ? -12.346 50.674  52.436 1.00 58.27  ? 672 THR C CA  1 
ATOM   8869  C C   . THR C 1 470 ? -11.343 49.847  53.228 1.00 57.18  ? 672 THR C C   1 
ATOM   8870  O O   . THR C 1 470 ? -10.292 50.346  53.639 1.00 55.96  ? 672 THR C O   1 
ATOM   8871  C CB  . THR C 1 470 ? -11.730 51.123  51.113 1.00 59.10  ? 672 THR C CB  1 
ATOM   8872  O OG1 . THR C 1 470 ? -12.701 51.854  50.356 1.00 63.76  ? 672 THR C OG1 1 
ATOM   8873  C CG2 . THR C 1 470 ? -11.277 49.915  50.308 1.00 59.47  ? 672 THR C CG2 1 
ATOM   8874  N N   . GLN C 1 471 ? -11.670 48.576  53.434 1.00 53.69  ? 673 GLN C N   1 
ATOM   8875  C CA  . GLN C 1 471 ? -11.011 47.796  54.466 1.00 52.95  ? 673 GLN C CA  1 
ATOM   8876  C C   . GLN C 1 471 ? -11.088 46.319  54.111 1.00 52.12  ? 673 GLN C C   1 
ATOM   8877  O O   . GLN C 1 471 ? -12.066 45.866  53.512 1.00 53.97  ? 673 GLN C O   1 
ATOM   8878  C CB  . GLN C 1 471 ? -11.684 48.080  55.808 1.00 48.38  ? 673 GLN C CB  1 
ATOM   8879  C CG  . GLN C 1 471 ? -11.028 47.517  57.025 1.00 52.70  ? 673 GLN C CG  1 
ATOM   8880  C CD  . GLN C 1 471 ? -11.701 48.038  58.270 1.00 56.02  ? 673 GLN C CD  1 
ATOM   8881  O OE1 . GLN C 1 471 ? -12.601 48.871  58.192 1.00 58.54  ? 673 GLN C OE1 1 
ATOM   8882  N NE2 . GLN C 1 471 ? -11.277 47.556  59.421 1.00 55.52  ? 673 GLN C NE2 1 
ATOM   8883  N N   . TYR C 1 472 ? -10.056 45.571  54.496 1.00 48.08  ? 674 TYR C N   1 
ATOM   8884  C CA  . TYR C 1 472 ? -10.093 44.121  54.369 1.00 46.78  ? 674 TYR C CA  1 
ATOM   8885  C C   . TYR C 1 472 ? -9.183  43.520  55.427 1.00 45.76  ? 674 TYR C C   1 
ATOM   8886  O O   . TYR C 1 472 ? -8.336  44.202  56.006 1.00 45.54  ? 674 TYR C O   1 
ATOM   8887  C CB  . TYR C 1 472 ? -9.680  43.646  52.969 1.00 44.29  ? 674 TYR C CB  1 
ATOM   8888  C CG  . TYR C 1 472 ? -8.219  43.832  52.633 1.00 44.49  ? 674 TYR C CG  1 
ATOM   8889  C CD1 . TYR C 1 472 ? -7.296  42.825  52.885 1.00 44.76  ? 674 TYR C CD1 1 
ATOM   8890  C CD2 . TYR C 1 472 ? -7.762  45.004  52.053 1.00 45.10  ? 674 TYR C CD2 1 
ATOM   8891  C CE1 . TYR C 1 472 ? -5.963  42.984  52.576 1.00 45.68  ? 674 TYR C CE1 1 
ATOM   8892  C CE2 . TYR C 1 472 ? -6.427  45.170  51.740 1.00 45.71  ? 674 TYR C CE2 1 
ATOM   8893  C CZ  . TYR C 1 472 ? -5.536  44.157  52.001 1.00 46.53  ? 674 TYR C CZ  1 
ATOM   8894  O OH  . TYR C 1 472 ? -4.209  44.319  51.695 1.00 46.70  ? 674 TYR C OH  1 
ATOM   8895  N N   . SER C 1 473 ? -9.368  42.227  55.672 1.00 40.00  ? 675 SER C N   1 
ATOM   8896  C CA  . SER C 1 473 ? -8.636  41.520  56.709 1.00 39.92  ? 675 SER C CA  1 
ATOM   8897  C C   . SER C 1 473 ? -8.115  40.197  56.168 1.00 39.68  ? 675 SER C C   1 
ATOM   8898  O O   . SER C 1 473 ? -8.577  39.686  55.146 1.00 39.90  ? 675 SER C O   1 
ATOM   8899  C CB  . SER C 1 473 ? -9.511  41.296  57.949 1.00 39.81  ? 675 SER C CB  1 
ATOM   8900  O OG  . SER C 1 473 ? -10.659 40.526  57.637 1.00 43.25  ? 675 SER C OG  1 
ATOM   8901  N N   . THR C 1 474 ? -7.128  39.651  56.872 1.00 40.19  ? 676 THR C N   1 
ATOM   8902  C CA  . THR C 1 474 ? -6.428  38.451  56.444 1.00 40.57  ? 676 THR C CA  1 
ATOM   8903  C C   . THR C 1 474 ? -5.815  37.785  57.666 1.00 39.15  ? 676 THR C C   1 
ATOM   8904  O O   . THR C 1 474 ? -5.724  38.382  58.741 1.00 40.21  ? 676 THR C O   1 
ATOM   8905  C CB  . THR C 1 474 ? -5.345  38.764  55.406 1.00 41.45  ? 676 THR C CB  1 
ATOM   8906  O OG1 . THR C 1 474 ? -4.798  37.541  54.901 1.00 44.77  ? 676 THR C OG1 1 
ATOM   8907  C CG2 . THR C 1 474 ? -4.231  39.589  56.031 1.00 41.01  ? 676 THR C CG2 1 
ATOM   8908  N N   . GLY C 1 475 ? -5.399  36.538  57.494 1.00 36.61  ? 677 GLY C N   1 
ATOM   8909  C CA  . GLY C 1 475 ? -4.838  35.801  58.607 1.00 34.94  ? 677 GLY C CA  1 
ATOM   8910  C C   . GLY C 1 475 ? -4.647  34.343  58.266 1.00 34.96  ? 677 GLY C C   1 
ATOM   8911  O O   . GLY C 1 475 ? -4.504  33.977  57.099 1.00 34.94  ? 677 GLY C O   1 
ATOM   8912  N N   . GLN C 1 476 ? -4.647  33.511  59.304 1.00 33.00  ? 678 GLN C N   1 
ATOM   8913  C CA  . GLN C 1 476 ? -4.383  32.088  59.175 1.00 33.55  ? 678 GLN C CA  1 
ATOM   8914  C C   . GLN C 1 476 ? -5.584  31.285  59.660 1.00 34.38  ? 678 GLN C C   1 
ATOM   8915  O O   . GLN C 1 476 ? -6.345  31.734  60.520 1.00 33.82  ? 678 GLN C O   1 
ATOM   8916  C CB  . GLN C 1 476 ? -3.158  31.692  59.988 1.00 34.44  ? 678 GLN C CB  1 
ATOM   8917  C CG  . GLN C 1 476 ? -1.898  32.488  59.676 1.00 36.51  ? 678 GLN C CG  1 
ATOM   8918  C CD  . GLN C 1 476 ? -1.436  32.353  58.249 1.00 38.32  ? 678 GLN C CD  1 
ATOM   8919  O OE1 . GLN C 1 476 ? -1.472  31.269  57.672 1.00 39.70  ? 678 GLN C OE1 1 
ATOM   8920  N NE2 . GLN C 1 476 ? -0.991  33.458  57.668 1.00 38.00  ? 678 GLN C NE2 1 
ATOM   8921  N N   . VAL C 1 477 ? -5.750  30.088  59.100 1.00 33.50  ? 679 VAL C N   1 
ATOM   8922  C CA  . VAL C 1 477 ? -6.770  29.138  59.532 1.00 33.85  ? 679 VAL C CA  1 
ATOM   8923  C C   . VAL C 1 477 ? -6.156  27.751  59.614 1.00 34.98  ? 679 VAL C C   1 
ATOM   8924  O O   . VAL C 1 477 ? -5.663  27.224  58.613 1.00 35.02  ? 679 VAL C O   1 
ATOM   8925  C CB  . VAL C 1 477 ? -7.990  29.120  58.591 1.00 32.27  ? 679 VAL C CB  1 
ATOM   8926  C CG1 . VAL C 1 477 ? -8.843  27.910  58.875 1.00 33.68  ? 679 VAL C CG1 1 
ATOM   8927  C CG2 . VAL C 1 477 ? -8.820  30.344  58.816 1.00 33.83  ? 679 VAL C CG2 1 
ATOM   8928  N N   . SER C 1 478 ? -6.208  27.153  60.799 1.00 32.97  ? 680 SER C N   1 
ATOM   8929  C CA  . SER C 1 478 ? -5.760  25.785  61.001 1.00 34.34  ? 680 SER C CA  1 
ATOM   8930  C C   . SER C 1 478 ? -6.944  24.922  61.407 1.00 34.17  ? 680 SER C C   1 
ATOM   8931  O O   . SER C 1 478 ? -7.773  25.336  62.221 1.00 34.90  ? 680 SER C O   1 
ATOM   8932  C CB  . SER C 1 478 ? -4.667  25.704  62.062 1.00 34.46  ? 680 SER C CB  1 
ATOM   8933  O OG  . SER C 1 478 ? -5.165  26.082  63.329 1.00 40.23  ? 680 SER C OG  1 
ATOM   8934  N N   . VAL C 1 479 ? -7.020  23.722  60.837 1.00 33.03  ? 681 VAL C N   1 
ATOM   8935  C CA  . VAL C 1 479 ? -8.111  22.794  61.103 1.00 32.93  ? 681 VAL C CA  1 
ATOM   8936  C C   . VAL C 1 479 ? -7.522  21.410  61.349 1.00 33.47  ? 681 VAL C C   1 
ATOM   8937  O O   . VAL C 1 479 ? -6.531  21.024  60.721 1.00 33.10  ? 681 VAL C O   1 
ATOM   8938  C CB  . VAL C 1 479 ? -9.137  22.780  59.946 1.00 29.58  ? 681 VAL C CB  1 
ATOM   8939  C CG1 . VAL C 1 479 ? -8.508  22.279  58.661 1.00 28.12  ? 681 VAL C CG1 1 
ATOM   8940  C CG2 . VAL C 1 479 ? -10.355 21.960  60.314 1.00 31.88  ? 681 VAL C CG2 1 
ATOM   8941  N N   . GLU C 1 480 ? -8.116  20.678  62.287 1.00 30.97  ? 682 GLU C N   1 
ATOM   8942  C CA  . GLU C 1 480 ? -7.623  19.376  62.716 1.00 32.15  ? 682 GLU C CA  1 
ATOM   8943  C C   . GLU C 1 480 ? -8.796  18.423  62.875 1.00 31.10  ? 682 GLU C C   1 
ATOM   8944  O O   . GLU C 1 480 ? -9.748  18.728  63.599 1.00 32.21  ? 682 GLU C O   1 
ATOM   8945  C CB  . GLU C 1 480 ? -6.857  19.496  64.035 1.00 32.77  ? 682 GLU C CB  1 
ATOM   8946  C CG  . GLU C 1 480 ? -6.307  18.192  64.571 1.00 41.65  ? 682 GLU C CG  1 
ATOM   8947  C CD  . GLU C 1 480 ? -5.534  18.385  65.859 1.00 48.17  ? 682 GLU C CD  1 
ATOM   8948  O OE1 . GLU C 1 480 ? -5.445  19.537  66.330 1.00 51.72  ? 682 GLU C OE1 1 
ATOM   8949  O OE2 . GLU C 1 480 ? -5.020  17.388  66.408 1.00 52.44  ? 682 GLU C OE2 1 
ATOM   8950  N N   . ILE C 1 481 ? -8.733  17.274  62.203 1.00 27.98  ? 683 ILE C N   1 
ATOM   8951  C CA  . ILE C 1 481 ? -9.769  16.253  62.306 1.00 26.38  ? 683 ILE C CA  1 
ATOM   8952  C C   . ILE C 1 481 ? -9.125  14.926  62.674 1.00 27.87  ? 683 ILE C C   1 
ATOM   8953  O O   . ILE C 1 481 ? -8.147  14.509  62.046 1.00 28.38  ? 683 ILE C O   1 
ATOM   8954  C CB  . ILE C 1 481 ? -10.583 16.106  61.008 1.00 24.01  ? 683 ILE C CB  1 
ATOM   8955  C CG1 . ILE C 1 481 ? -11.390 17.367  60.742 1.00 23.38  ? 683 ILE C CG1 1 
ATOM   8956  C CG2 . ILE C 1 481 ? -11.527 14.930  61.100 1.00 21.42  ? 683 ILE C CG2 1 
ATOM   8957  C CD1 . ILE C 1 481 ? -12.130 17.334  59.441 1.00 22.87  ? 683 ILE C CD1 1 
ATOM   8958  N N   . GLU C 1 482 ? -9.677  14.267  63.686 1.00 26.21  ? 684 GLU C N   1 
ATOM   8959  C CA  . GLU C 1 482 ? -9.268  12.924  64.063 1.00 27.69  ? 684 GLU C CA  1 
ATOM   8960  C C   . GLU C 1 482 ? -10.154 11.912  63.349 1.00 26.54  ? 684 GLU C C   1 
ATOM   8961  O O   . GLU C 1 482 ? -11.382 11.972  63.452 1.00 26.70  ? 684 GLU C O   1 
ATOM   8962  C CB  . GLU C 1 482 ? -9.365  12.751  65.577 1.00 28.33  ? 684 GLU C CB  1 
ATOM   8963  C CG  . GLU C 1 482 ? -8.903  11.410  66.101 1.00 37.91  ? 684 GLU C CG  1 
ATOM   8964  C CD  . GLU C 1 482 ? -8.992  11.336  67.611 1.00 44.62  ? 684 GLU C CD  1 
ATOM   8965  O OE1 . GLU C 1 482 ? -9.465  12.314  68.224 1.00 47.67  ? 684 GLU C OE1 1 
ATOM   8966  O OE2 . GLU C 1 482 ? -8.583  10.312  68.191 1.00 48.50  ? 684 GLU C OE2 1 
ATOM   8967  N N   . TRP C 1 483 ? -9.530  10.993  62.621 1.00 25.91  ? 685 TRP C N   1 
ATOM   8968  C CA  . TRP C 1 483 ? -10.233 9.992   61.834 1.00 25.56  ? 685 TRP C CA  1 
ATOM   8969  C C   . TRP C 1 483 ? -10.026 8.623   62.464 1.00 26.50  ? 685 TRP C C   1 
ATOM   8970  O O   . TRP C 1 483 ? -8.927  8.309   62.924 1.00 26.41  ? 685 TRP C O   1 
ATOM   8971  C CB  . TRP C 1 483 ? -9.722  9.985   60.391 1.00 20.21  ? 685 TRP C CB  1 
ATOM   8972  C CG  . TRP C 1 483 ? -9.947  11.273  59.651 1.00 19.21  ? 685 TRP C CG  1 
ATOM   8973  C CD1 . TRP C 1 483 ? -9.106  12.340  59.608 1.00 19.14  ? 685 TRP C CD1 1 
ATOM   8974  C CD2 . TRP C 1 483 ? -11.063 11.609  58.816 1.00 18.52  ? 685 TRP C CD2 1 
ATOM   8975  N NE1 . TRP C 1 483 ? -9.634  13.331  58.821 1.00 18.21  ? 685 TRP C NE1 1 
ATOM   8976  C CE2 . TRP C 1 483 ? -10.834 12.906  58.319 1.00 18.81  ? 685 TRP C CE2 1 
ATOM   8977  C CE3 . TRP C 1 483 ? -12.234 10.945  58.446 1.00 18.71  ? 685 TRP C CE3 1 
ATOM   8978  C CZ2 . TRP C 1 483 ? -11.733 13.550  57.476 1.00 19.04  ? 685 TRP C CZ2 1 
ATOM   8979  C CZ3 . TRP C 1 483 ? -13.121 11.585  57.609 1.00 19.00  ? 685 TRP C CZ3 1 
ATOM   8980  C CH2 . TRP C 1 483 ? -12.870 12.875  57.136 1.00 19.64  ? 685 TRP C CH2 1 
ATOM   8981  N N   . GLU C 1 484 ? -11.076 7.808   62.491 1.00 24.03  ? 686 GLU C N   1 
ATOM   8982  C CA  . GLU C 1 484 ? -10.980 6.444   62.993 1.00 25.72  ? 686 GLU C CA  1 
ATOM   8983  C C   . GLU C 1 484 ? -11.003 5.460   61.832 1.00 24.38  ? 686 GLU C C   1 
ATOM   8984  O O   . GLU C 1 484 ? -11.832 5.576   60.927 1.00 23.32  ? 686 GLU C O   1 
ATOM   8985  C CB  . GLU C 1 484 ? -12.113 6.122   63.966 1.00 23.91  ? 686 GLU C CB  1 
ATOM   8986  C CG  . GLU C 1 484 ? -11.994 4.737   64.577 1.00 32.64  ? 686 GLU C CG  1 
ATOM   8987  C CD  . GLU C 1 484 ? -13.096 4.427   65.565 1.00 38.48  ? 686 GLU C CD  1 
ATOM   8988  O OE1 . GLU C 1 484 ? -13.987 5.280   65.750 1.00 40.28  ? 686 GLU C OE1 1 
ATOM   8989  O OE2 . GLU C 1 484 ? -13.072 3.327   66.155 1.00 40.25  ? 686 GLU C OE2 1 
ATOM   8990  N N   . LEU C 1 485 ? -10.112 4.474   61.880 1.00 21.84  ? 687 LEU C N   1 
ATOM   8991  C CA  . LEU C 1 485 ? -9.862  3.585   60.757 1.00 22.51  ? 687 LEU C CA  1 
ATOM   8992  C C   . LEU C 1 485 ? -10.365 2.178   61.041 1.00 25.39  ? 687 LEU C C   1 
ATOM   8993  O O   . LEU C 1 485 ? -10.415 1.735   62.191 1.00 26.09  ? 687 LEU C O   1 
ATOM   8994  C CB  . LEU C 1 485 ? -8.373  3.503   60.440 1.00 23.61  ? 687 LEU C CB  1 
ATOM   8995  C CG  . LEU C 1 485 ? -7.654  4.792   60.087 1.00 21.52  ? 687 LEU C CG  1 
ATOM   8996  C CD1 . LEU C 1 485 ? -6.190  4.482   59.887 1.00 20.45  ? 687 LEU C CD1 1 
ATOM   8997  C CD2 . LEU C 1 485 ? -8.268  5.416   58.859 1.00 20.86  ? 687 LEU C CD2 1 
ATOM   8998  N N   . GLN C 1 486 ? -10.721 1.474   59.965 1.00 18.70  ? 688 GLN C N   1 
ATOM   8999  C CA  . GLN C 1 486 ? -11.133 0.075   60.021 1.00 22.01  ? 688 GLN C CA  1 
ATOM   9000  C C   . GLN C 1 486 ? -10.141 -0.742  59.187 1.00 24.07  ? 688 GLN C C   1 
ATOM   9001  O O   . GLN C 1 486 ? -10.100 -0.643  57.961 1.00 24.86  ? 688 GLN C O   1 
ATOM   9002  C CB  . GLN C 1 486 ? -12.561 -0.088  59.524 1.00 17.64  ? 688 GLN C CB  1 
ATOM   9003  C CG  . GLN C 1 486 ? -13.106 -1.484  59.663 1.00 23.24  ? 688 GLN C CG  1 
ATOM   9004  C CD  . GLN C 1 486 ? -14.559 -1.564  59.267 1.00 28.33  ? 688 GLN C CD  1 
ATOM   9005  O OE1 . GLN C 1 486 ? -15.189 -0.548  58.986 1.00 30.93  ? 688 GLN C OE1 1 
ATOM   9006  N NE2 . GLN C 1 486 ? -15.099 -2.775  59.230 1.00 29.52  ? 688 GLN C NE2 1 
ATOM   9007  N N   . LYS C 1 487 ? -9.347  -1.566  59.868 1.00 24.44  ? 689 LYS C N   1 
ATOM   9008  C CA  . LYS C 1 487 ? -8.222  -2.240  59.232 1.00 27.19  ? 689 LYS C CA  1 
ATOM   9009  C C   . LYS C 1 487 ? -8.679  -3.380  58.334 1.00 27.69  ? 689 LYS C C   1 
ATOM   9010  O O   . LYS C 1 487 ? -9.799  -3.878  58.452 1.00 26.28  ? 689 LYS C O   1 
ATOM   9011  C CB  . LYS C 1 487 ? -7.254  -2.764  60.292 1.00 25.60  ? 689 LYS C CB  1 
ATOM   9012  C CG  . LYS C 1 487 ? -6.616  -1.663  61.114 1.00 30.60  ? 689 LYS C CG  1 
ATOM   9013  C CD  . LYS C 1 487 ? -5.709  -0.800  60.252 1.00 35.16  ? 689 LYS C CD  1 
ATOM   9014  C CE  . LYS C 1 487 ? -5.077  0.312   61.062 1.00 37.91  ? 689 LYS C CE  1 
ATOM   9015  N NZ  . LYS C 1 487 ? -4.175  -0.226  62.120 1.00 37.24  ? 689 LYS C NZ  1 
ATOM   9016  N N   . GLU C 1 488 ? -7.788  -3.784  57.432 1.00 29.42  ? 690 GLU C N   1 
ATOM   9017  C CA  . GLU C 1 488 ? -8.077  -4.844  56.477 1.00 31.41  ? 690 GLU C CA  1 
ATOM   9018  C C   . GLU C 1 488 ? -7.630  -6.202  57.010 1.00 30.33  ? 690 GLU C C   1 
ATOM   9019  O O   . GLU C 1 488 ? -6.439  -6.457  57.197 1.00 31.11  ? 690 GLU C O   1 
ATOM   9020  C CB  . GLU C 1 488 ? -7.402  -4.521  55.143 1.00 20.66  ? 690 GLU C CB  1 
ATOM   9021  C CG  . GLU C 1 488 ? -7.433  -5.610  54.090 1.00 28.55  ? 690 GLU C CG  1 
ATOM   9022  C CD  . GLU C 1 488 ? -6.223  -6.526  54.175 1.00 33.68  ? 690 GLU C CD  1 
ATOM   9023  O OE1 . GLU C 1 488 ? -5.178  -6.085  54.696 1.00 36.30  ? 690 GLU C OE1 1 
ATOM   9024  O OE2 . GLU C 1 488 ? -6.305  -7.680  53.714 1.00 34.38  ? 690 GLU C OE2 1 
ATOM   9025  N N   . ASN C 1 489 ? -8.608  -7.068  57.266 1.00 33.08  ? 691 ASN C N   1 
ATOM   9026  C CA  . ASN C 1 489 ? -8.445  -8.371  57.906 1.00 31.47  ? 691 ASN C CA  1 
ATOM   9027  C C   . ASN C 1 489 ? -8.416  -9.497  56.868 1.00 29.58  ? 691 ASN C C   1 
ATOM   9028  O O   . ASN C 1 489 ? -8.404  -10.680 57.210 1.00 27.95  ? 691 ASN C O   1 
ATOM   9029  C CB  . ASN C 1 489 ? -9.566  -8.590  58.923 1.00 35.01  ? 691 ASN C CB  1 
ATOM   9030  C CG  . ASN C 1 489 ? -9.251  -9.670  59.947 1.00 38.57  ? 691 ASN C CG  1 
ATOM   9031  O OD1 . ASN C 1 489 ? -8.336  -10.473 59.778 1.00 39.99  ? 691 ASN C OD1 1 
ATOM   9032  N ND2 . ASN C 1 489 ? -10.030 -9.695  61.021 1.00 38.90  ? 691 ASN C ND2 1 
ATOM   9033  N N   . SER C 1 490 ? -8.430  -9.152  55.584 1.00 26.32  ? 692 SER C N   1 
ATOM   9034  C CA  . SER C 1 490 ? -8.741  -10.119 54.534 1.00 23.77  ? 692 SER C CA  1 
ATOM   9035  C C   . SER C 1 490 ? -7.757  -11.287 54.488 1.00 21.63  ? 692 SER C C   1 
ATOM   9036  O O   . SER C 1 490 ? -6.564  -11.144 54.764 1.00 22.04  ? 692 SER C O   1 
ATOM   9037  C CB  . SER C 1 490 ? -8.767  -9.429  53.170 1.00 20.41  ? 692 SER C CB  1 
ATOM   9038  O OG  . SER C 1 490 ? -9.037  -10.352 52.132 1.00 21.31  ? 692 SER C OG  1 
ATOM   9039  N N   . LYS C 1 491 ? -8.289  -12.461 54.141 1.00 21.52  ? 693 LYS C N   1 
ATOM   9040  C CA  . LYS C 1 491 ? -7.516  -13.681 53.927 1.00 18.12  ? 693 LYS C CA  1 
ATOM   9041  C C   . LYS C 1 491 ? -7.206  -13.938 52.460 1.00 15.94  ? 693 LYS C C   1 
ATOM   9042  O O   . LYS C 1 491 ? -6.678  -15.006 52.130 1.00 14.87  ? 693 LYS C O   1 
ATOM   9043  C CB  . LYS C 1 491 ? -8.250  -14.887 54.505 1.00 19.87  ? 693 LYS C CB  1 
ATOM   9044  C CG  . LYS C 1 491 ? -8.457  -14.817 55.985 1.00 20.78  ? 693 LYS C CG  1 
ATOM   9045  C CD  . LYS C 1 491 ? -7.137  -14.734 56.711 1.00 22.43  ? 693 LYS C CD  1 
ATOM   9046  C CE  . LYS C 1 491 ? -6.428  -16.068 56.682 1.00 24.11  ? 693 LYS C CE  1 
ATOM   9047  N NZ  . LYS C 1 491 ? -5.190  -16.033 57.499 1.00 24.84  ? 693 LYS C NZ  1 
ATOM   9048  N N   . ARG C 1 492 ? -7.555  -13.008 51.578 1.00 14.67  ? 694 ARG C N   1 
ATOM   9049  C CA  . ARG C 1 492 ? -7.305  -13.164 50.153 1.00 13.00  ? 694 ARG C CA  1 
ATOM   9050  C C   . ARG C 1 492 ? -5.854  -13.548 49.888 1.00 12.71  ? 694 ARG C C   1 
ATOM   9051  O O   . ARG C 1 492 ? -4.929  -12.946 50.438 1.00 12.93  ? 694 ARG C O   1 
ATOM   9052  C CB  . ARG C 1 492 ? -7.659  -11.862 49.440 1.00 12.22  ? 694 ARG C CB  1 
ATOM   9053  C CG  . ARG C 1 492 ? -7.282  -11.818 47.992 1.00 12.64  ? 694 ARG C CG  1 
ATOM   9054  C CD  . ARG C 1 492 ? -7.808  -10.569 47.332 1.00 13.57  ? 694 ARG C CD  1 
ATOM   9055  N NE  . ARG C 1 492 ? -7.350  -10.421 45.957 1.00 14.68  ? 694 ARG C NE  1 
ATOM   9056  C CZ  . ARG C 1 492 ? -7.867  -9.558  45.094 1.00 16.06  ? 694 ARG C CZ  1 
ATOM   9057  N NH1 . ARG C 1 492 ? -8.878  -8.791  45.459 1.00 15.43  ? 694 ARG C NH1 1 
ATOM   9058  N NH2 . ARG C 1 492 ? -7.390  -9.476  43.863 1.00 15.65  ? 694 ARG C NH2 1 
ATOM   9059  N N   . TRP C 1 493 ? -5.660  -14.578 49.061 1.00 10.88  ? 695 TRP C N   1 
ATOM   9060  C CA  . TRP C 1 493 ? -4.312  -15.071 48.799 1.00 9.63   ? 695 TRP C CA  1 
ATOM   9061  C C   . TRP C 1 493 ? -3.577  -14.188 47.798 1.00 10.55  ? 695 TRP C C   1 
ATOM   9062  O O   . TRP C 1 493 ? -2.443  -13.768 48.046 1.00 10.19  ? 695 TRP C O   1 
ATOM   9063  C CB  . TRP C 1 493 ? -4.371  -16.509 48.286 1.00 11.79  ? 695 TRP C CB  1 
ATOM   9064  C CG  . TRP C 1 493 ? -3.032  -17.079 47.964 1.00 12.07  ? 695 TRP C CG  1 
ATOM   9065  C CD1 . TRP C 1 493 ? -2.464  -17.180 46.735 1.00 11.88  ? 695 TRP C CD1 1 
ATOM   9066  C CD2 . TRP C 1 493 ? -2.101  -17.645 48.886 1.00 12.89  ? 695 TRP C CD2 1 
ATOM   9067  N NE1 . TRP C 1 493 ? -1.227  -17.759 46.832 1.00 11.57  ? 695 TRP C NE1 1 
ATOM   9068  C CE2 . TRP C 1 493 ? -0.982  -18.058 48.144 1.00 12.74  ? 695 TRP C CE2 1 
ATOM   9069  C CE3 . TRP C 1 493 ? -2.102  -17.839 50.268 1.00 12.38  ? 695 TRP C CE3 1 
ATOM   9070  C CZ2 . TRP C 1 493 ? 0.121   -18.653 48.735 1.00 13.05  ? 695 TRP C CZ2 1 
ATOM   9071  C CZ3 . TRP C 1 493 ? -1.009  -18.431 50.852 1.00 11.75  ? 695 TRP C CZ3 1 
ATOM   9072  C CH2 . TRP C 1 493 ? 0.091   -18.829 50.088 1.00 13.40  ? 695 TRP C CH2 1 
ATOM   9073  N N   . ASN C 1 494 ? -4.205  -13.891 46.667 1.00 9.67   ? 696 ASN C N   1 
ATOM   9074  C CA  . ASN C 1 494 ? -3.550  -13.116 45.628 1.00 9.88   ? 696 ASN C CA  1 
ATOM   9075  C C   . ASN C 1 494 ? -3.505  -11.638 46.006 1.00 10.65  ? 696 ASN C C   1 
ATOM   9076  O O   . ASN C 1 494 ? -4.274  -11.179 46.851 1.00 11.47  ? 696 ASN C O   1 
ATOM   9077  C CB  . ASN C 1 494 ? -4.264  -13.307 44.295 1.00 12.94  ? 696 ASN C CB  1 
ATOM   9078  C CG  . ASN C 1 494 ? -5.724  -12.956 44.365 1.00 11.90  ? 696 ASN C CG  1 
ATOM   9079  O OD1 . ASN C 1 494 ? -6.320  -12.984 45.430 1.00 12.56  ? 696 ASN C OD1 1 
ATOM   9080  N ND2 . ASN C 1 494 ? -6.298  -12.575 43.240 1.00 11.83  ? 696 ASN C ND2 1 
ATOM   9081  N N   . PRO C 1 495 ? -2.590  -10.883 45.389 1.00 10.78  ? 697 PRO C N   1 
ATOM   9082  C CA  . PRO C 1 495 ? -2.441  -9.454  45.693 1.00 11.37  ? 697 PRO C CA  1 
ATOM   9083  C C   . PRO C 1 495 ? -3.557  -8.542  45.180 1.00 12.32  ? 697 PRO C C   1 
ATOM   9084  O O   . PRO C 1 495 ? -4.031  -8.686  44.071 1.00 11.99  ? 697 PRO C O   1 
ATOM   9085  C CB  . PRO C 1 495 ? -1.096  -9.092  45.059 1.00 9.46   ? 697 PRO C CB  1 
ATOM   9086  C CG  . PRO C 1 495 ? -0.820  -10.156 44.073 1.00 11.32  ? 697 PRO C CG  1 
ATOM   9087  C CD  . PRO C 1 495 ? -1.510  -11.394 44.535 1.00 9.50   ? 697 PRO C CD  1 
ATOM   9088  N N   . GLU C 1 496 ? -3.947  -7.596  46.024 1.00 11.74  ? 698 GLU C N   1 
ATOM   9089  C CA  . GLU C 1 496 ? -4.993  -6.612  45.761 1.00 13.62  ? 698 GLU C CA  1 
ATOM   9090  C C   . GLU C 1 496 ? -4.618  -5.509  44.789 1.00 12.42  ? 698 GLU C C   1 
ATOM   9091  O O   . GLU C 1 496 ? -3.452  -5.249  44.554 1.00 12.04  ? 698 GLU C O   1 
ATOM   9092  C CB  . GLU C 1 496 ? -5.363  -5.921  47.068 1.00 9.28   ? 698 GLU C CB  1 
ATOM   9093  C CG  . GLU C 1 496 ? -5.825  -6.841  48.172 1.00 17.69  ? 698 GLU C CG  1 
ATOM   9094  C CD  . GLU C 1 496 ? -7.328  -6.912  48.255 1.00 23.42  ? 698 GLU C CD  1 
ATOM   9095  O OE1 . GLU C 1 496 ? -7.990  -6.443  47.310 1.00 25.09  ? 698 GLU C OE1 1 
ATOM   9096  O OE2 . GLU C 1 496 ? -7.845  -7.431  49.265 1.00 25.30  ? 698 GLU C OE2 1 
ATOM   9097  N N   . ILE C 1 497 ? -5.626  -4.882  44.199 1.00 13.53  ? 699 ILE C N   1 
ATOM   9098  C CA  . ILE C 1 497 ? -5.411  -3.741  43.326 1.00 13.50  ? 699 ILE C CA  1 
ATOM   9099  C C   . ILE C 1 497 ? -5.110  -2.543  44.227 1.00 12.91  ? 699 ILE C C   1 
ATOM   9100  O O   . ILE C 1 497 ? -5.733  -2.380  45.263 1.00 12.63  ? 699 ILE C O   1 
ATOM   9101  C CB  . ILE C 1 497 ? -6.646  -3.463  42.463 1.00 9.95   ? 699 ILE C CB  1 
ATOM   9102  C CG1 . ILE C 1 497 ? -6.953  -4.678  41.600 1.00 11.33  ? 699 ILE C CG1 1 
ATOM   9103  C CG2 . ILE C 1 497 ? -6.430  -2.247  41.588 1.00 10.40  ? 699 ILE C CG2 1 
ATOM   9104  C CD1 . ILE C 1 497 ? -7.934  -4.403  40.491 1.00 15.69  ? 699 ILE C CD1 1 
ATOM   9105  N N   . GLN C 1 498 ? -4.157  -1.705  43.845 1.00 11.86  ? 700 GLN C N   1 
ATOM   9106  C CA  . GLN C 1 498 ? -3.798  -0.560  44.661 1.00 11.32  ? 700 GLN C CA  1 
ATOM   9107  C C   . GLN C 1 498 ? -3.717  0.691   43.822 1.00 11.65  ? 700 GLN C C   1 
ATOM   9108  O O   . GLN C 1 498 ? -3.506  0.612   42.624 1.00 12.37  ? 700 GLN C O   1 
ATOM   9109  C CB  . GLN C 1 498 ? -2.441  -0.792  45.306 1.00 10.12  ? 700 GLN C CB  1 
ATOM   9110  C CG  . GLN C 1 498 ? -2.329  -2.059  46.122 1.00 11.17  ? 700 GLN C CG  1 
ATOM   9111  C CD  . GLN C 1 498 ? -2.737  -1.867  47.559 1.00 11.46  ? 700 GLN C CD  1 
ATOM   9112  O OE1 . GLN C 1 498 ? -1.895  -1.717  48.431 1.00 11.44  ? 700 GLN C OE1 1 
ATOM   9113  N NE2 . GLN C 1 498 ? -4.030  -1.865  47.812 1.00 10.71  ? 700 GLN C NE2 1 
ATOM   9114  N N   . TYR C 1 499 ? -3.916  1.852   44.436 1.00 10.70  ? 701 TYR C N   1 
ATOM   9115  C CA  . TYR C 1 499 ? -3.800  3.090   43.690 1.00 10.80  ? 701 TYR C CA  1 
ATOM   9116  C C   . TYR C 1 499 ? -2.321  3.375   43.639 1.00 12.05  ? 701 TYR C C   1 
ATOM   9117  O O   . TYR C 1 499 ? -1.674  3.454   44.666 1.00 11.87  ? 701 TYR C O   1 
ATOM   9118  C CB  . TYR C 1 499 ? -4.533  4.252   44.349 1.00 10.80  ? 701 TYR C CB  1 
ATOM   9119  C CG  . TYR C 1 499 ? -4.163  5.541   43.678 1.00 11.73  ? 701 TYR C CG  1 
ATOM   9120  C CD1 . TYR C 1 499 ? -4.749  5.912   42.482 1.00 12.95  ? 701 TYR C CD1 1 
ATOM   9121  C CD2 . TYR C 1 499 ? -3.180  6.354   44.202 1.00 11.86  ? 701 TYR C CD2 1 
ATOM   9122  C CE1 . TYR C 1 499 ? -4.385  7.074   41.844 1.00 13.97  ? 701 TYR C CE1 1 
ATOM   9123  C CE2 . TYR C 1 499 ? -2.811  7.516   43.570 1.00 14.11  ? 701 TYR C CE2 1 
ATOM   9124  C CZ  . TYR C 1 499 ? -3.418  7.867   42.393 1.00 14.91  ? 701 TYR C CZ  1 
ATOM   9125  O OH  . TYR C 1 499 ? -3.048  9.025   41.763 1.00 15.58  ? 701 TYR C OH  1 
ATOM   9126  N N   . THR C 1 500 ? -1.784  3.547   42.445 1.00 8.27   ? 702 THR C N   1 
ATOM   9127  C CA  . THR C 1 500 ? -0.357  3.742   42.281 1.00 11.88  ? 702 THR C CA  1 
ATOM   9128  C C   . THR C 1 500 ? -0.096  4.930   41.373 1.00 14.48  ? 702 THR C C   1 
ATOM   9129  O O   . THR C 1 500 ? -0.910  5.284   40.518 1.00 14.80  ? 702 THR C O   1 
ATOM   9130  C CB  . THR C 1 500 ? 0.319   2.483   41.717 1.00 12.33  ? 702 THR C CB  1 
ATOM   9131  O OG1 . THR C 1 500 ? 1.735   2.679   41.668 1.00 12.76  ? 702 THR C OG1 1 
ATOM   9132  C CG2 . THR C 1 500 ? -0.194  2.165   40.328 1.00 11.04  ? 702 THR C CG2 1 
ATOM   9133  N N   . SER C 1 501 ? 1.097   5.485   41.496 1.00 10.01  ? 703 SER C N   1 
ATOM   9134  C CA  . SER C 1 501 ? 1.531   6.561   40.637 1.00 14.82  ? 703 SER C CA  1 
ATOM   9135  C C   . SER C 1 501 ? 2.219   5.830   39.490 1.00 18.20  ? 703 SER C C   1 
ATOM   9136  O O   . SER C 1 501 ? 3.060   4.979   39.729 1.00 18.84  ? 703 SER C O   1 
ATOM   9137  C CB  . SER C 1 501 ? 2.519   7.441   41.387 1.00 14.65  ? 703 SER C CB  1 
ATOM   9138  O OG  . SER C 1 501 ? 2.940   8.534   40.604 1.00 16.26  ? 703 SER C OG  1 
ATOM   9139  N N   . ASN C 1 502 ? 1.843   6.110   38.250 1.00 15.63  ? 704 ASN C N   1 
ATOM   9140  C CA  . ASN C 1 502 ? 2.454   5.429   37.111 1.00 20.36  ? 704 ASN C CA  1 
ATOM   9141  C C   . ASN C 1 502 ? 3.898   5.840   36.914 1.00 22.59  ? 704 ASN C C   1 
ATOM   9142  O O   . ASN C 1 502 ? 4.241   6.993   37.123 1.00 23.49  ? 704 ASN C O   1 
ATOM   9143  C CB  . ASN C 1 502 ? 1.680   5.726   35.837 1.00 22.69  ? 704 ASN C CB  1 
ATOM   9144  C CG  . ASN C 1 502 ? 0.247   6.106   36.110 1.00 25.56  ? 704 ASN C CG  1 
ATOM   9145  O OD1 . ASN C 1 502 ? -0.296  7.007   35.480 1.00 27.31  ? 704 ASN C OD1 1 
ATOM   9146  N ND2 . ASN C 1 502 ? -0.372  5.429   37.063 1.00 25.97  ? 704 ASN C ND2 1 
ATOM   9147  N N   . TYR C 1 503 ? 4.754   4.910   36.509 1.00 20.36  ? 705 TYR C N   1 
ATOM   9148  C CA  . TYR C 1 503 ? 6.141   5.278   36.292 1.00 23.66  ? 705 TYR C CA  1 
ATOM   9149  C C   . TYR C 1 503 ? 6.538   5.379   34.829 1.00 23.43  ? 705 TYR C C   1 
ATOM   9150  O O   . TYR C 1 503 ? 6.809   4.377   34.178 1.00 23.28  ? 705 TYR C O   1 
ATOM   9151  C CB  . TYR C 1 503 ? 7.069   4.279   36.972 1.00 19.89  ? 705 TYR C CB  1 
ATOM   9152  C CG  . TYR C 1 503 ? 8.526   4.665   36.877 1.00 26.30  ? 705 TYR C CG  1 
ATOM   9153  C CD1 . TYR C 1 503 ? 9.203   5.162   37.979 1.00 28.90  ? 705 TYR C CD1 1 
ATOM   9154  C CD2 . TYR C 1 503 ? 9.220   4.548   35.684 1.00 27.97  ? 705 TYR C CD2 1 
ATOM   9155  C CE1 . TYR C 1 503 ? 10.531  5.521   37.899 1.00 30.35  ? 705 TYR C CE1 1 
ATOM   9156  C CE2 . TYR C 1 503 ? 10.552  4.902   35.596 1.00 29.24  ? 705 TYR C CE2 1 
ATOM   9157  C CZ  . TYR C 1 503 ? 11.199  5.390   36.708 1.00 30.46  ? 705 TYR C CZ  1 
ATOM   9158  O OH  . TYR C 1 503 ? 12.521  5.752   36.633 1.00 28.94  ? 705 TYR C OH  1 
ATOM   9159  N N   . TYR C 1 504 ? 6.583   6.602   34.328 1.00 24.18  ? 706 TYR C N   1 
ATOM   9160  C CA  . TYR C 1 504 ? 7.031   6.882   32.972 1.00 23.59  ? 706 TYR C CA  1 
ATOM   9161  C C   . TYR C 1 504 ? 7.443   8.344   32.921 1.00 19.75  ? 706 TYR C C   1 
ATOM   9162  O O   . TYR C 1 504 ? 7.005   9.136   33.737 1.00 18.80  ? 706 TYR C O   1 
ATOM   9163  C CB  . TYR C 1 504 ? 6.009   6.496   31.891 1.00 15.40  ? 706 TYR C CB  1 
ATOM   9164  C CG  . TYR C 1 504 ? 4.628   7.090   32.021 1.00 23.45  ? 706 TYR C CG  1 
ATOM   9165  C CD1 . TYR C 1 504 ? 4.338   8.348   31.515 1.00 26.22  ? 706 TYR C CD1 1 
ATOM   9166  C CD2 . TYR C 1 504 ? 3.602   6.375   32.611 1.00 25.52  ? 706 TYR C CD2 1 
ATOM   9167  C CE1 . TYR C 1 504 ? 3.071   8.886   31.621 1.00 28.49  ? 706 TYR C CE1 1 
ATOM   9168  C CE2 . TYR C 1 504 ? 2.334   6.903   32.719 1.00 28.49  ? 706 TYR C CE2 1 
ATOM   9169  C CZ  . TYR C 1 504 ? 2.074   8.155   32.225 1.00 29.49  ? 706 TYR C CZ  1 
ATOM   9170  O OH  . TYR C 1 504 ? 0.809   8.674   32.337 1.00 29.88  ? 706 TYR C OH  1 
ATOM   9171  N N   . LYS C 1 505 ? 8.282   8.716   31.972 1.00 22.90  ? 707 LYS C N   1 
ATOM   9172  C CA  . LYS C 1 505 ? 8.715   10.095  31.913 1.00 19.13  ? 707 LYS C CA  1 
ATOM   9173  C C   . LYS C 1 505 ? 7.613   11.015  31.431 1.00 17.58  ? 707 LYS C C   1 
ATOM   9174  O O   . LYS C 1 505 ? 6.852   10.670  30.541 1.00 17.04  ? 707 LYS C O   1 
ATOM   9175  C CB  . LYS C 1 505 ? 9.963   10.234  31.044 1.00 20.29  ? 707 LYS C CB  1 
ATOM   9176  C CG  . LYS C 1 505 ? 9.911   9.462   29.743 1.00 19.24  ? 707 LYS C CG  1 
ATOM   9177  C CD  . LYS C 1 505 ? 11.055  9.859   28.834 1.00 18.89  ? 707 LYS C CD  1 
ATOM   9178  C CE  . LYS C 1 505 ? 10.956  9.142   27.503 1.00 19.25  ? 707 LYS C CE  1 
ATOM   9179  N NZ  . LYS C 1 505 ? 11.996  9.612   26.549 1.00 20.59  ? 707 LYS C NZ  1 
ATOM   9180  N N   . SER C 1 506 ? 7.536   12.190  32.042 1.00 21.53  ? 708 SER C N   1 
ATOM   9181  C CA  . SER C 1 506 ? 6.547   13.194  31.681 1.00 20.53  ? 708 SER C CA  1 
ATOM   9182  C C   . SER C 1 506 ? 7.082   14.571  32.041 1.00 19.04  ? 708 SER C C   1 
ATOM   9183  O O   . SER C 1 506 ? 8.035   14.709  32.810 1.00 17.78  ? 708 SER C O   1 
ATOM   9184  C CB  . SER C 1 506 ? 5.203   12.940  32.373 1.00 23.05  ? 708 SER C CB  1 
ATOM   9185  O OG  . SER C 1 506 ? 5.322   13.036  33.780 1.00 25.48  ? 708 SER C OG  1 
ATOM   9186  N N   . ASN C 1 507 ? 6.448   15.595  31.470 1.00 21.16  ? 709 ASN C N   1 
ATOM   9187  C CA  . ASN C 1 507 ? 6.905   16.963  31.685 1.00 21.19  ? 709 ASN C CA  1 
ATOM   9188  C C   . ASN C 1 507 ? 6.640   17.418  33.114 1.00 20.47  ? 709 ASN C C   1 
ATOM   9189  O O   . ASN C 1 507 ? 7.226   18.402  33.579 1.00 20.94  ? 709 ASN C O   1 
ATOM   9190  C CB  . ASN C 1 507 ? 6.222   17.900  30.693 1.00 22.64  ? 709 ASN C CB  1 
ATOM   9191  C CG  . ASN C 1 507 ? 6.634   17.634  29.267 1.00 24.41  ? 709 ASN C CG  1 
ATOM   9192  O OD1 . ASN C 1 507 ? 7.695   17.074  29.012 1.00 23.95  ? 709 ASN C OD1 1 
ATOM   9193  N ND2 . ASN C 1 507 ? 5.793   18.034  28.326 1.00 27.00  ? 709 ASN C ND2 1 
ATOM   9194  N N   . ASN C 1 508 ? 5.759   16.720  33.822 1.00 21.97  ? 710 ASN C N   1 
ATOM   9195  C CA  . ASN C 1 508 ? 5.385   17.061  35.183 1.00 21.01  ? 710 ASN C CA  1 
ATOM   9196  C C   . ASN C 1 508 ? 5.167   15.776  35.968 1.00 19.84  ? 710 ASN C C   1 
ATOM   9197  O O   . ASN C 1 508 ? 5.047   14.692  35.395 1.00 20.51  ? 710 ASN C O   1 
ATOM   9198  C CB  . ASN C 1 508 ? 4.105   17.904  35.211 1.00 21.41  ? 710 ASN C CB  1 
ATOM   9199  C CG  . ASN C 1 508 ? 4.225   19.182  34.407 1.00 23.84  ? 710 ASN C CG  1 
ATOM   9200  O OD1 . ASN C 1 508 ? 3.374   19.480  33.571 1.00 26.10  ? 710 ASN C OD1 1 
ATOM   9201  N ND2 . ASN C 1 508 ? 5.274   19.948  34.659 1.00 24.46  ? 710 ASN C ND2 1 
ATOM   9202  N N   . VAL C 1 509 ? 5.115   15.897  37.284 1.00 20.52  ? 711 VAL C N   1 
ATOM   9203  C CA  . VAL C 1 509 ? 4.641   14.800  38.118 1.00 17.37  ? 711 VAL C CA  1 
ATOM   9204  C C   . VAL C 1 509 ? 3.222   15.115  38.561 1.00 18.07  ? 711 VAL C C   1 
ATOM   9205  O O   . VAL C 1 509 ? 2.871   16.275  38.801 1.00 17.60  ? 711 VAL C O   1 
ATOM   9206  C CB  . VAL C 1 509 ? 5.570   14.553  39.323 1.00 18.02  ? 711 VAL C CB  1 
ATOM   9207  C CG1 . VAL C 1 509 ? 6.948   14.133  38.852 1.00 16.86  ? 711 VAL C CG1 1 
ATOM   9208  C CG2 . VAL C 1 509 ? 5.655   15.763  40.206 1.00 16.97  ? 711 VAL C CG2 1 
ATOM   9209  N N   . GLU C 1 510 ? 2.395   14.080  38.648 1.00 20.19  ? 712 GLU C N   1 
ATOM   9210  C CA  . GLU C 1 510 ? 0.985   14.280  38.938 1.00 20.57  ? 712 GLU C CA  1 
ATOM   9211  C C   . GLU C 1 510 ? 0.797   14.750  40.372 1.00 18.63  ? 712 GLU C C   1 
ATOM   9212  O O   . GLU C 1 510 ? 1.532   14.346  41.275 1.00 19.20  ? 712 GLU C O   1 
ATOM   9213  C CB  . GLU C 1 510 ? 0.216   12.985  38.690 1.00 19.82  ? 712 GLU C CB  1 
ATOM   9214  C CG  . GLU C 1 510 ? 0.228   12.560  37.236 1.00 27.99  ? 712 GLU C CG  1 
ATOM   9215  C CD  . GLU C 1 510 ? -0.477  11.244  37.004 1.00 33.32  ? 712 GLU C CD  1 
ATOM   9216  O OE1 . GLU C 1 510 ? -0.831  10.575  37.996 1.00 34.24  ? 712 GLU C OE1 1 
ATOM   9217  O OE2 . GLU C 1 510 ? -0.675  10.876  35.827 1.00 36.20  ? 712 GLU C OE2 1 
ATOM   9218  N N   . PHE C 1 511 ? -0.197  15.616  40.570 1.00 19.77  ? 713 PHE C N   1 
ATOM   9219  C CA  . PHE C 1 511 ? -0.490  16.210  41.874 1.00 17.28  ? 713 PHE C CA  1 
ATOM   9220  C C   . PHE C 1 511 ? 0.675   17.058  42.373 1.00 15.94  ? 713 PHE C C   1 
ATOM   9221  O O   . PHE C 1 511 ? 1.075   16.972  43.534 1.00 16.24  ? 713 PHE C O   1 
ATOM   9222  C CB  . PHE C 1 511 ? -0.863  15.144  42.904 1.00 16.04  ? 713 PHE C CB  1 
ATOM   9223  C CG  . PHE C 1 511 ? -2.124  14.403  42.584 1.00 15.06  ? 713 PHE C CG  1 
ATOM   9224  C CD1 . PHE C 1 511 ? -3.355  14.917  42.944 1.00 15.32  ? 713 PHE C CD1 1 
ATOM   9225  C CD2 . PHE C 1 511 ? -2.078  13.190  41.925 1.00 15.25  ? 713 PHE C CD2 1 
ATOM   9226  C CE1 . PHE C 1 511 ? -4.512  14.237  42.653 1.00 15.56  ? 713 PHE C CE1 1 
ATOM   9227  C CE2 . PHE C 1 511 ? -3.233  12.507  41.632 1.00 15.90  ? 713 PHE C CE2 1 
ATOM   9228  C CZ  . PHE C 1 511 ? -4.452  13.031  41.995 1.00 16.32  ? 713 PHE C CZ  1 
ATOM   9229  N N   . ALA C 1 512 ? 1.226   17.882  41.486 1.00 17.27  ? 714 ALA C N   1 
ATOM   9230  C CA  . ALA C 1 512 ? 2.263   18.828  41.862 1.00 16.09  ? 714 ALA C CA  1 
ATOM   9231  C C   . ALA C 1 512 ? 2.133   20.081  41.013 1.00 16.45  ? 714 ALA C C   1 
ATOM   9232  O O   . ALA C 1 512 ? 1.263   20.182  40.146 1.00 15.74  ? 714 ALA C O   1 
ATOM   9233  C CB  . ALA C 1 512 ? 3.663   18.235  41.708 1.00 16.64  ? 714 ALA C CB  1 
ATOM   9234  N N   . VAL C 1 513 ? 3.015   21.042  41.285 1.00 16.34  ? 715 VAL C N   1 
ATOM   9235  C CA  . VAL C 1 513 ? 2.997   22.307  40.566 1.00 17.25  ? 715 VAL C CA  1 
ATOM   9236  C C   . VAL C 1 513 ? 3.709   22.164  39.228 1.00 18.16  ? 715 VAL C C   1 
ATOM   9237  O O   . VAL C 1 513 ? 4.578   21.304  39.042 1.00 17.95  ? 715 VAL C O   1 
ATOM   9238  C CB  . VAL C 1 513 ? 3.634   23.421  41.412 1.00 15.72  ? 715 VAL C CB  1 
ATOM   9239  C CG1 . VAL C 1 513 ? 2.813   23.673  42.661 1.00 16.89  ? 715 VAL C CG1 1 
ATOM   9240  C CG2 . VAL C 1 513 ? 5.049   23.052  41.773 1.00 16.85  ? 715 VAL C CG2 1 
ATOM   9241  N N   . ASN C 1 514 ? 3.327   23.012  38.281 1.00 19.36  ? 716 ASN C N   1 
ATOM   9242  C CA  . ASN C 1 514 ? 3.989   23.096  36.990 1.00 20.96  ? 716 ASN C CA  1 
ATOM   9243  C C   . ASN C 1 514 ? 4.999   24.245  37.016 1.00 21.47  ? 716 ASN C C   1 
ATOM   9244  O O   . ASN C 1 514 ? 5.311   24.803  38.071 1.00 22.65  ? 716 ASN C O   1 
ATOM   9245  C CB  . ASN C 1 514 ? 2.954   23.226  35.876 1.00 20.31  ? 716 ASN C CB  1 
ATOM   9246  C CG  . ASN C 1 514 ? 2.085   24.453  36.024 1.00 23.00  ? 716 ASN C CG  1 
ATOM   9247  O OD1 . ASN C 1 514 ? 2.052   25.078  37.077 1.00 28.71  ? 716 ASN C OD1 1 
ATOM   9248  N ND2 . ASN C 1 514 ? 1.369   24.800  34.965 1.00 24.74  ? 716 ASN C ND2 1 
ATOM   9249  N N   . THR C 1 515 ? 5.547   24.594  35.849 1.00 23.58  ? 717 THR C N   1 
ATOM   9250  C CA  . THR C 1 515 ? 6.602   25.600  35.800 1.00 23.37  ? 717 THR C CA  1 
ATOM   9251  C C   . THR C 1 515 ? 6.082   26.992  36.119 1.00 24.79  ? 717 THR C C   1 
ATOM   9252  O O   . THR C 1 515 ? 6.874   27.899  36.397 1.00 23.91  ? 717 THR C O   1 
ATOM   9253  C CB  . THR C 1 515 ? 7.269   25.603  34.426 1.00 23.57  ? 717 THR C CB  1 
ATOM   9254  O OG1 . THR C 1 515 ? 6.286   25.872  33.422 1.00 22.26  ? 717 THR C OG1 1 
ATOM   9255  C CG2 . THR C 1 515 ? 7.911   24.265  34.145 1.00 22.98  ? 717 THR C CG2 1 
ATOM   9256  N N   . GLU C 1 516 ? 4.769   27.191  36.068 1.00 23.94  ? 718 GLU C N   1 
ATOM   9257  C CA  . GLU C 1 516 ? 4.193   28.500  36.341 1.00 25.88  ? 718 GLU C CA  1 
ATOM   9258  C C   . GLU C 1 516 ? 3.705   28.655  37.774 1.00 24.19  ? 718 GLU C C   1 
ATOM   9259  O O   . GLU C 1 516 ? 3.231   29.736  38.132 1.00 24.27  ? 718 GLU C O   1 
ATOM   9260  C CB  . GLU C 1 516 ? 3.045   28.774  35.370 1.00 22.49  ? 718 GLU C CB  1 
ATOM   9261  C CG  . GLU C 1 516 ? 3.476   28.867  33.918 1.00 33.33  ? 718 GLU C CG  1 
ATOM   9262  C CD  . GLU C 1 516 ? 4.513   29.949  33.682 1.00 38.91  ? 718 GLU C CD  1 
ATOM   9263  O OE1 . GLU C 1 516 ? 4.418   31.020  34.316 1.00 42.42  ? 718 GLU C OE1 1 
ATOM   9264  O OE2 . GLU C 1 516 ? 5.420   29.731  32.853 1.00 41.71  ? 718 GLU C OE2 1 
ATOM   9265  N N   . GLY C 1 517 ? 3.807   27.619  38.597 1.00 26.47  ? 719 GLY C N   1 
ATOM   9266  C CA  . GLY C 1 517 ? 3.326   27.678  39.959 1.00 23.36  ? 719 GLY C CA  1 
ATOM   9267  C C   . GLY C 1 517 ? 1.883   27.272  40.155 1.00 21.05  ? 719 GLY C C   1 
ATOM   9268  O O   . GLY C 1 517 ? 1.287   27.648  41.170 1.00 21.36  ? 719 GLY C O   1 
ATOM   9269  N N   . VAL C 1 518 ? 1.306   26.519  39.227 1.00 21.43  ? 720 VAL C N   1 
ATOM   9270  C CA  . VAL C 1 518 ? -0.096  26.130  39.298 1.00 19.17  ? 720 VAL C CA  1 
ATOM   9271  C C   . VAL C 1 518 ? -0.191  24.663  39.694 1.00 19.64  ? 720 VAL C C   1 
ATOM   9272  O O   . VAL C 1 518 ? 0.299   23.781  38.980 1.00 19.99  ? 720 VAL C O   1 
ATOM   9273  C CB  . VAL C 1 518 ? -0.800  26.386  37.957 1.00 24.23  ? 720 VAL C CB  1 
ATOM   9274  C CG1 . VAL C 1 518 ? -2.221  25.879  38.005 1.00 20.81  ? 720 VAL C CG1 1 
ATOM   9275  C CG2 . VAL C 1 518 ? -0.766  27.864  37.624 1.00 21.70  ? 720 VAL C CG2 1 
ATOM   9276  N N   . TYR C 1 519 ? -0.837  24.401  40.826 1.00 17.46  ? 721 TYR C N   1 
ATOM   9277  C CA  . TYR C 1 519 ? -0.975  23.059  41.372 1.00 18.61  ? 721 TYR C CA  1 
ATOM   9278  C C   . TYR C 1 519 ? -2.279  22.436  40.899 1.00 19.44  ? 721 TYR C C   1 
ATOM   9279  O O   . TYR C 1 519 ? -3.357  22.869  41.312 1.00 19.08  ? 721 TYR C O   1 
ATOM   9280  C CB  . TYR C 1 519 ? -0.950  23.093  42.898 1.00 15.92  ? 721 TYR C CB  1 
ATOM   9281  C CG  . TYR C 1 519 ? -1.279  21.765  43.532 1.00 16.37  ? 721 TYR C CG  1 
ATOM   9282  C CD1 . TYR C 1 519 ? -0.319  20.778  43.657 1.00 15.76  ? 721 TYR C CD1 1 
ATOM   9283  C CD2 . TYR C 1 519 ? -2.561  21.491  43.986 1.00 15.83  ? 721 TYR C CD2 1 
ATOM   9284  C CE1 . TYR C 1 519 ? -0.622  19.567  44.230 1.00 16.39  ? 721 TYR C CE1 1 
ATOM   9285  C CE2 . TYR C 1 519 ? -2.871  20.282  44.552 1.00 17.32  ? 721 TYR C CE2 1 
ATOM   9286  C CZ  . TYR C 1 519 ? -1.899  19.324  44.672 1.00 17.44  ? 721 TYR C CZ  1 
ATOM   9287  O OH  . TYR C 1 519 ? -2.204  18.116  45.244 1.00 17.90  ? 721 TYR C OH  1 
ATOM   9288  N N   . SER C 1 520 ? -2.180  21.392  40.080 1.00 14.97  ? 722 SER C N   1 
ATOM   9289  C CA  . SER C 1 520 ? -3.351  20.763  39.489 1.00 17.08  ? 722 SER C CA  1 
ATOM   9290  C C   . SER C 1 520 ? -3.494  19.335  39.993 1.00 18.46  ? 722 SER C C   1 
ATOM   9291  O O   . SER C 1 520 ? -2.514  18.698  40.383 1.00 19.41  ? 722 SER C O   1 
ATOM   9292  C CB  . SER C 1 520 ? -3.265  20.758  37.962 1.00 16.01  ? 722 SER C CB  1 
ATOM   9293  O OG  . SER C 1 520 ? -2.165  19.980  37.528 1.00 19.49  ? 722 SER C OG  1 
ATOM   9294  N N   . GLU C 1 521 ? -4.732  18.842  39.980 1.00 16.22  ? 723 GLU C N   1 
ATOM   9295  C CA  . GLU C 1 521 ? -5.034  17.452  40.306 1.00 17.22  ? 723 GLU C CA  1 
ATOM   9296  C C   . GLU C 1 521 ? -5.504  16.727  39.053 1.00 16.69  ? 723 GLU C C   1 
ATOM   9297  O O   . GLU C 1 521 ? -6.619  16.986  38.576 1.00 17.38  ? 723 GLU C O   1 
ATOM   9298  C CB  . GLU C 1 521 ? -6.096  17.368  41.401 1.00 14.26  ? 723 GLU C CB  1 
ATOM   9299  C CG  . GLU C 1 521 ? -5.606  17.808  42.765 1.00 18.04  ? 723 GLU C CG  1 
ATOM   9300  C CD  . GLU C 1 521 ? -6.694  17.760  43.812 1.00 20.48  ? 723 GLU C CD  1 
ATOM   9301  O OE1 . GLU C 1 521 ? -7.874  17.621  43.438 1.00 21.26  ? 723 GLU C OE1 1 
ATOM   9302  O OE2 . GLU C 1 521 ? -6.368  17.843  45.012 1.00 21.13  ? 723 GLU C OE2 1 
ATOM   9303  N N   . PRO C 1 522 ? -4.708  15.813  38.493 1.00 17.01  ? 724 PRO C N   1 
ATOM   9304  C CA  . PRO C 1 522 ? -5.020  15.305  37.149 1.00 17.17  ? 724 PRO C CA  1 
ATOM   9305  C C   . PRO C 1 522 ? -6.225  14.383  37.089 1.00 17.39  ? 724 PRO C C   1 
ATOM   9306  O O   . PRO C 1 522 ? -6.887  14.315  36.046 1.00 17.73  ? 724 PRO C O   1 
ATOM   9307  C CB  . PRO C 1 522 ? -3.730  14.578  36.757 1.00 16.07  ? 724 PRO C CB  1 
ATOM   9308  C CG  . PRO C 1 522 ? -3.165  14.119  38.049 1.00 17.16  ? 724 PRO C CG  1 
ATOM   9309  C CD  . PRO C 1 522 ? -3.516  15.168  39.067 1.00 16.03  ? 724 PRO C CD  1 
ATOM   9310  N N   . ARG C 1 523 ? -6.525  13.655  38.159 1.00 16.65  ? 725 ARG C N   1 
ATOM   9311  C CA  . ARG C 1 523 ? -7.616  12.689  38.104 1.00 16.73  ? 725 ARG C CA  1 
ATOM   9312  C C   . ARG C 1 523 ? -8.326  12.557  39.446 1.00 15.86  ? 725 ARG C C   1 
ATOM   9313  O O   . ARG C 1 523 ? -7.744  12.868  40.491 1.00 15.79  ? 725 ARG C O   1 
ATOM   9314  C CB  . ARG C 1 523 ? -7.090  11.331  37.637 1.00 12.81  ? 725 ARG C CB  1 
ATOM   9315  C CG  . ARG C 1 523 ? -5.948  10.766  38.459 1.00 17.40  ? 725 ARG C CG  1 
ATOM   9316  C CD  . ARG C 1 523 ? -5.561  9.396   37.939 1.00 24.86  ? 725 ARG C CD  1 
ATOM   9317  N NE  . ARG C 1 523 ? -4.429  8.820   38.655 1.00 33.58  ? 725 ARG C NE  1 
ATOM   9318  C CZ  . ARG C 1 523 ? -3.874  7.652   38.348 1.00 37.17  ? 725 ARG C CZ  1 
ATOM   9319  N NH1 . ARG C 1 523 ? -2.842  7.200   39.043 1.00 37.80  ? 725 ARG C NH1 1 
ATOM   9320  N NH2 . ARG C 1 523 ? -4.356  6.932   37.346 1.00 37.35  ? 725 ARG C NH2 1 
ATOM   9321  N N   . PRO C 1 524 ? -9.590  12.128  39.458 1.00 17.17  ? 726 PRO C N   1 
ATOM   9322  C CA  . PRO C 1 524 ? -10.248 11.820  40.732 1.00 16.16  ? 726 PRO C CA  1 
ATOM   9323  C C   . PRO C 1 524 ? -9.769  10.497  41.305 1.00 14.75  ? 726 PRO C C   1 
ATOM   9324  O O   . PRO C 1 524 ? -9.567  9.537   40.557 1.00 15.01  ? 726 PRO C O   1 
ATOM   9325  C CB  . PRO C 1 524 ? -11.731 11.768  40.353 1.00 14.29  ? 726 PRO C CB  1 
ATOM   9326  C CG  . PRO C 1 524 ? -11.723 11.329  38.938 1.00 15.39  ? 726 PRO C CG  1 
ATOM   9327  C CD  . PRO C 1 524 ? -10.491 11.921  38.311 1.00 15.14  ? 726 PRO C CD  1 
ATOM   9328  N N   . ILE C 1 525 ? -9.587  10.423  42.618 1.00 16.86  ? 727 ILE C N   1 
ATOM   9329  C CA  . ILE C 1 525 ? -9.125  9.205   43.267 1.00 14.23  ? 727 ILE C CA  1 
ATOM   9330  C C   . ILE C 1 525 ? -10.267 8.651   44.103 1.00 13.60  ? 727 ILE C C   1 
ATOM   9331  O O   . ILE C 1 525 ? -10.635 9.233   45.128 1.00 13.17  ? 727 ILE C O   1 
ATOM   9332  C CB  . ILE C 1 525 ? -7.891  9.459   44.143 1.00 12.53  ? 727 ILE C CB  1 
ATOM   9333  C CG1 . ILE C 1 525 ? -6.741  10.040  43.329 1.00 11.96  ? 727 ILE C CG1 1 
ATOM   9334  C CG2 . ILE C 1 525 ? -7.423  8.162   44.747 1.00 10.75  ? 727 ILE C CG2 1 
ATOM   9335  C CD1 . ILE C 1 525 ? -5.600  10.508  44.196 1.00 13.13  ? 727 ILE C CD1 1 
ATOM   9336  N N   . GLY C 1 526 ? -10.821 7.522   43.674 1.00 15.26  ? 728 GLY C N   1 
ATOM   9337  C CA  . GLY C 1 526 ? -11.834 6.853   44.455 1.00 15.25  ? 728 GLY C CA  1 
ATOM   9338  C C   . GLY C 1 526 ? -11.264 6.239   45.716 1.00 15.62  ? 728 GLY C C   1 
ATOM   9339  O O   . GLY C 1 526 ? -10.059 6.231   45.958 1.00 15.52  ? 728 GLY C O   1 
ATOM   9340  N N   . THR C 1 527 ? -12.160 5.741   46.556 1.00 14.92  ? 729 THR C N   1 
ATOM   9341  C CA  . THR C 1 527 ? -11.753 5.138   47.815 1.00 16.82  ? 729 THR C CA  1 
ATOM   9342  C C   . THR C 1 527 ? -11.739 3.609   47.778 1.00 17.27  ? 729 THR C C   1 
ATOM   9343  O O   . THR C 1 527 ? -11.328 2.985   48.759 1.00 19.78  ? 729 THR C O   1 
ATOM   9344  C CB  . THR C 1 527 ? -12.675 5.641   48.926 1.00 16.50  ? 729 THR C CB  1 
ATOM   9345  O OG1 . THR C 1 527 ? -12.845 7.048   48.763 1.00 19.26  ? 729 THR C OG1 1 
ATOM   9346  C CG2 . THR C 1 527 ? -12.029 5.464   50.268 1.00 16.36  ? 729 THR C CG2 1 
ATOM   9347  N N   . ARG C 1 528 ? -12.141 2.984   46.674 1.00 17.55  ? 730 ARG C N   1 
ATOM   9348  C CA  . ARG C 1 528 ? -12.414 1.545   46.657 1.00 16.95  ? 730 ARG C CA  1 
ATOM   9349  C C   . ARG C 1 528 ? -11.370 0.809   45.824 1.00 17.56  ? 730 ARG C C   1 
ATOM   9350  O O   . ARG C 1 528 ? -11.385 0.857   44.593 1.00 18.05  ? 730 ARG C O   1 
ATOM   9351  C CB  . ARG C 1 528 ? -13.831 1.305   46.152 1.00 20.75  ? 730 ARG C CB  1 
ATOM   9352  C CG  . ARG C 1 528 ? -14.851 1.747   47.171 1.00 19.20  ? 730 ARG C CG  1 
ATOM   9353  C CD  . ARG C 1 528 ? -16.267 1.705   46.667 1.00 18.33  ? 730 ARG C CD  1 
ATOM   9354  N NE  . ARG C 1 528 ? -17.181 2.083   47.738 1.00 17.98  ? 730 ARG C NE  1 
ATOM   9355  C CZ  . ARG C 1 528 ? -18.449 2.426   47.559 1.00 18.46  ? 730 ARG C CZ  1 
ATOM   9356  N NH1 . ARG C 1 528 ? -18.946 2.486   46.338 1.00 19.83  ? 730 ARG C NH1 1 
ATOM   9357  N NH2 . ARG C 1 528 ? -19.207 2.749   48.594 1.00 17.02  ? 730 ARG C NH2 1 
ATOM   9358  N N   . TYR C 1 529 ? -10.479 0.104   46.518 1.00 19.25  ? 731 TYR C N   1 
ATOM   9359  C CA  . TYR C 1 529 ? -9.395  -0.670  45.927 1.00 19.14  ? 731 TYR C CA  1 
ATOM   9360  C C   . TYR C 1 529 ? -9.359  -2.064  46.535 1.00 18.77  ? 731 TYR C C   1 
ATOM   9361  O O   . TYR C 1 529 ? -9.439  -3.062  45.815 1.00 18.31  ? 731 TYR C O   1 
ATOM   9362  C CB  . TYR C 1 529 ? -8.069  0.074   46.071 1.00 12.81  ? 731 TYR C CB  1 
ATOM   9363  C CG  . TYR C 1 529 ? -8.034  1.284   45.170 1.00 14.14  ? 731 TYR C CG  1 
ATOM   9364  C CD1 . TYR C 1 529 ? -7.613  1.174   43.855 1.00 14.91  ? 731 TYR C CD1 1 
ATOM   9365  C CD2 . TYR C 1 529 ? -8.463  2.522   45.616 1.00 14.14  ? 731 TYR C CD2 1 
ATOM   9366  C CE1 . TYR C 1 529 ? -7.602  2.262   43.018 1.00 15.98  ? 731 TYR C CE1 1 
ATOM   9367  C CE2 . TYR C 1 529 ? -8.457  3.617   44.784 1.00 15.57  ? 731 TYR C CE2 1 
ATOM   9368  C CZ  . TYR C 1 529 ? -8.026  3.481   43.487 1.00 16.48  ? 731 TYR C CZ  1 
ATOM   9369  O OH  . TYR C 1 529 ? -8.015  4.573   42.655 1.00 17.54  ? 731 TYR C OH  1 
ATOM   9370  N N   . LEU C 1 530 ? -9.217  -2.139  47.854 1.00 18.27  ? 732 LEU C N   1 
ATOM   9371  C CA  . LEU C 1 530 ? -9.273  -3.402  48.570 1.00 18.09  ? 732 LEU C CA  1 
ATOM   9372  C C   . LEU C 1 530 ? -10.644 -4.048  48.390 1.00 19.16  ? 732 LEU C C   1 
ATOM   9373  O O   . LEU C 1 530 ? -11.599 -3.413  47.949 1.00 19.45  ? 732 LEU C O   1 
ATOM   9374  C CB  . LEU C 1 530 ? -9.001  -3.185  50.056 1.00 16.98  ? 732 LEU C CB  1 
ATOM   9375  C CG  . LEU C 1 530 ? -7.651  -2.606  50.467 1.00 17.51  ? 732 LEU C CG  1 
ATOM   9376  C CD1 . LEU C 1 530 ? -7.630  -2.373  51.958 1.00 18.10  ? 732 LEU C CD1 1 
ATOM   9377  C CD2 . LEU C 1 530 ? -6.528  -3.520  50.063 1.00 15.53  ? 732 LEU C CD2 1 
ATOM   9378  N N   . THR C 1 531 ? -10.723 -5.346  48.676 1.00 18.28  ? 733 THR C N   1 
ATOM   9379  C CA  . THR C 1 531 ? -11.956 -6.090  48.462 1.00 18.80  ? 733 THR C CA  1 
ATOM   9380  C C   . THR C 1 531 ? -12.412 -6.782  49.739 1.00 19.10  ? 733 THR C C   1 
ATOM   9381  O O   . THR C 1 531 ? -11.663 -6.915  50.709 1.00 18.94  ? 733 THR C O   1 
ATOM   9382  C CB  . THR C 1 531 ? -11.804 -7.132  47.350 1.00 17.87  ? 733 THR C CB  1 
ATOM   9383  O OG1 . THR C 1 531 ? -10.793 -8.075  47.713 1.00 20.28  ? 733 THR C OG1 1 
ATOM   9384  C CG2 . THR C 1 531 ? -11.412 -6.460  46.056 1.00 17.81  ? 733 THR C CG2 1 
ATOM   9385  N N   . ARG C 1 532 ? -13.675 -7.204  49.723 1.00 15.68  ? 734 ARG C N   1 
ATOM   9386  C CA  . ARG C 1 532 ? -14.261 -8.043  50.756 1.00 17.21  ? 734 ARG C CA  1 
ATOM   9387  C C   . ARG C 1 532 ? -15.171 -9.073  50.107 1.00 18.83  ? 734 ARG C C   1 
ATOM   9388  O O   . ARG C 1 532 ? -15.540 -8.960  48.937 1.00 19.02  ? 734 ARG C O   1 
ATOM   9389  C CB  . ARG C 1 532 ? -15.088 -7.246  51.764 1.00 17.71  ? 734 ARG C CB  1 
ATOM   9390  C CG  . ARG C 1 532 ? -14.336 -6.389  52.743 1.00 20.43  ? 734 ARG C CG  1 
ATOM   9391  C CD  . ARG C 1 532 ? -15.354 -5.655  53.585 1.00 22.76  ? 734 ARG C CD  1 
ATOM   9392  N NE  . ARG C 1 532 ? -16.197 -6.598  54.307 1.00 27.81  ? 734 ARG C NE  1 
ATOM   9393  C CZ  . ARG C 1 532 ? -15.965 -7.031  55.540 1.00 30.95  ? 734 ARG C CZ  1 
ATOM   9394  N NH1 . ARG C 1 532 ? -14.933 -6.570  56.223 1.00 31.34  ? 734 ARG C NH1 1 
ATOM   9395  N NH2 . ARG C 1 532 ? -16.790 -7.898  56.106 1.00 32.22  ? 734 ARG C NH2 1 
ATOM   9396  N N   . ASN C 1 533 ? -15.542 -10.077 50.890 1.00 18.12  ? 735 ASN C N   1 
ATOM   9397  C CA  . ASN C 1 533 ? -16.585 -10.996 50.468 1.00 20.89  ? 735 ASN C CA  1 
ATOM   9398  C C   . ASN C 1 533 ? -17.955 -10.359 50.654 1.00 23.04  ? 735 ASN C C   1 
ATOM   9399  O O   . ASN C 1 533 ? -18.138 -9.440  51.455 1.00 23.42  ? 735 ASN C O   1 
ATOM   9400  C CB  . ASN C 1 533 ? -16.500 -12.302 51.250 1.00 21.65  ? 735 ASN C CB  1 
ATOM   9401  C CG  . ASN C 1 533 ? -15.313 -13.135 50.846 1.00 23.57  ? 735 ASN C CG  1 
ATOM   9402  O OD1 . ASN C 1 533 ? -14.824 -13.030 49.723 1.00 24.15  ? 735 ASN C OD1 1 
ATOM   9403  N ND2 . ASN C 1 533 ? -14.828 -13.957 51.764 1.00 24.27  ? 735 ASN C ND2 1 
ATOM   9404  N N   . LEU C 1 534 ? -18.922 -10.860 49.899 1.00 18.62  ? 736 LEU C N   1 
ATOM   9405  C CA  . LEU C 1 534 ? -20.271 -10.324 49.942 1.00 22.58  ? 736 LEU C CA  1 
ATOM   9406  C C   . LEU C 1 534 ? -21.104 -11.071 50.978 1.00 27.11  ? 736 LEU C C   1 
ATOM   9407  O O   . LEU C 1 534 ? -20.727 -11.156 52.147 1.00 29.46  ? 736 LEU C O   1 
ATOM   9408  C CB  . LEU C 1 534 ? -20.915 -10.416 48.561 1.00 21.98  ? 736 LEU C CB  1 
ATOM   9409  C CG  . LEU C 1 534 ? -22.245 -9.712  48.320 1.00 18.38  ? 736 LEU C CG  1 
ATOM   9410  C CD1 . LEU C 1 534 ? -22.383 -8.498  49.209 1.00 17.08  ? 736 LEU C CD1 1 
ATOM   9411  C CD2 . LEU C 1 534 ? -22.329 -9.315  46.869 1.00 16.80  ? 736 LEU C CD2 1 
ATOM   9412  N N   . ASP D 1 17  ? 8.112   39.141  72.725 1.00 77.92  ? 219 ASP D N   1 
ATOM   9413  C CA  . ASP D 1 17  ? 7.486   39.799  73.867 1.00 78.17  ? 219 ASP D CA  1 
ATOM   9414  C C   . ASP D 1 17  ? 6.655   40.999  73.422 1.00 75.88  ? 219 ASP D C   1 
ATOM   9415  O O   . ASP D 1 17  ? 5.428   40.979  73.516 1.00 75.92  ? 219 ASP D O   1 
ATOM   9416  C CB  . ASP D 1 17  ? 8.546   40.234  74.881 1.00 75.48  ? 219 ASP D CB  1 
ATOM   9417  C CG  . ASP D 1 17  ? 7.945   40.889  76.107 1.00 79.15  ? 219 ASP D CG  1 
ATOM   9418  O OD1 . ASP D 1 17  ? 7.243   40.192  76.870 1.00 80.93  ? 219 ASP D OD1 1 
ATOM   9419  O OD2 . ASP D 1 17  ? 8.178   42.098  76.313 1.00 80.25  ? 219 ASP D OD2 1 
ATOM   9420  N N   . GLY D 1 18  ? 7.323   42.042  72.933 1.00 75.29  ? 220 GLY D N   1 
ATOM   9421  C CA  . GLY D 1 18  ? 6.626   43.235  72.492 1.00 69.91  ? 220 GLY D CA  1 
ATOM   9422  C C   . GLY D 1 18  ? 7.428   44.018  71.475 1.00 66.56  ? 220 GLY D C   1 
ATOM   9423  O O   . GLY D 1 18  ? 8.623   43.781  71.273 1.00 67.29  ? 220 GLY D O   1 
ATOM   9424  N N   . VAL D 1 19  ? 6.744   44.967  70.833 1.00 67.88  ? 221 VAL D N   1 
ATOM   9425  C CA  . VAL D 1 19  ? 7.396   45.818  69.843 1.00 63.65  ? 221 VAL D CA  1 
ATOM   9426  C C   . VAL D 1 19  ? 8.345   46.797  70.522 1.00 62.52  ? 221 VAL D C   1 
ATOM   9427  O O   . VAL D 1 19  ? 9.431   47.091  70.007 1.00 63.38  ? 221 VAL D O   1 
ATOM   9428  C CB  . VAL D 1 19  ? 6.340   46.550  68.996 1.00 62.95  ? 221 VAL D CB  1 
ATOM   9429  C CG1 . VAL D 1 19  ? 7.005   47.513  68.030 1.00 62.20  ? 221 VAL D CG1 1 
ATOM   9430  C CG2 . VAL D 1 19  ? 5.478   45.553  68.248 1.00 62.98  ? 221 VAL D CG2 1 
ATOM   9431  N N   . GLY D 1 20  ? 7.959   47.312  71.683 1.00 65.58  ? 222 GLY D N   1 
ATOM   9432  C CA  . GLY D 1 20  ? 8.767   48.249  72.429 1.00 63.07  ? 222 GLY D CA  1 
ATOM   9433  C C   . GLY D 1 20  ? 9.833   47.625  73.299 1.00 62.80  ? 222 GLY D C   1 
ATOM   9434  O O   . GLY D 1 20  ? 10.348  48.295  74.200 1.00 63.03  ? 222 GLY D O   1 
ATOM   9435  N N   . SER D 1 21  ? 10.173  46.361  73.069 1.00 64.46  ? 223 SER D N   1 
ATOM   9436  C CA  . SER D 1 21  ? 11.217  45.673  73.812 1.00 63.02  ? 223 SER D CA  1 
ATOM   9437  C C   . SER D 1 21  ? 12.014  44.793  72.863 1.00 61.74  ? 223 SER D C   1 
ATOM   9438  O O   . SER D 1 21  ? 11.462  44.229  71.914 1.00 63.43  ? 223 SER D O   1 
ATOM   9439  C CB  . SER D 1 21  ? 10.630  44.826  74.942 1.00 64.69  ? 223 SER D CB  1 
ATOM   9440  O OG  . SER D 1 21  ? 11.652  44.127  75.632 1.00 69.73  ? 223 SER D OG  1 
ATOM   9441  N N   . SER D 1 22  ? 13.312  44.682  73.122 1.00 62.96  ? 224 SER D N   1 
ATOM   9442  C CA  . SER D 1 22  ? 14.185  43.880  72.279 1.00 61.24  ? 224 SER D CA  1 
ATOM   9443  C C   . SER D 1 22  ? 14.149  42.422  72.717 1.00 59.66  ? 224 SER D C   1 
ATOM   9444  O O   . SER D 1 22  ? 14.046  42.116  73.908 1.00 58.36  ? 224 SER D O   1 
ATOM   9445  C CB  . SER D 1 22  ? 15.617  44.412  72.328 1.00 54.67  ? 224 SER D CB  1 
ATOM   9446  O OG  . SER D 1 22  ? 16.478  43.622  71.530 1.00 58.82  ? 224 SER D OG  1 
ATOM   9447  N N   . SER D 1 23  ? 14.219  41.522  71.739 1.00 59.07  ? 225 SER D N   1 
ATOM   9448  C CA  . SER D 1 23  ? 14.127  40.090  71.980 1.00 58.41  ? 225 SER D CA  1 
ATOM   9449  C C   . SER D 1 23  ? 15.483  39.404  72.081 1.00 58.19  ? 225 SER D C   1 
ATOM   9450  O O   . SER D 1 23  ? 15.530  38.184  72.257 1.00 59.30  ? 225 SER D O   1 
ATOM   9451  C CB  . SER D 1 23  ? 13.294  39.429  70.879 1.00 54.79  ? 225 SER D CB  1 
ATOM   9452  O OG  . SER D 1 23  ? 13.911  39.580  69.614 1.00 56.70  ? 225 SER D OG  1 
ATOM   9453  N N   . GLY D 1 24  ? 16.579  40.145  71.973 1.00 55.89  ? 226 GLY D N   1 
ATOM   9454  C CA  . GLY D 1 24  ? 17.891  39.534  72.086 1.00 55.56  ? 226 GLY D CA  1 
ATOM   9455  C C   . GLY D 1 24  ? 18.980  40.569  71.929 1.00 55.63  ? 226 GLY D C   1 
ATOM   9456  O O   . GLY D 1 24  ? 18.768  41.651  71.376 1.00 56.26  ? 226 GLY D O   1 
ATOM   9457  N N   . ASN D 1 25  ? 20.163  40.208  72.414 1.00 52.74  ? 227 ASN D N   1 
ATOM   9458  C CA  . ASN D 1 25  ? 21.320  41.088  72.428 1.00 53.07  ? 227 ASN D CA  1 
ATOM   9459  C C   . ASN D 1 25  ? 22.298  40.673  71.340 1.00 54.72  ? 227 ASN D C   1 
ATOM   9460  O O   . ASN D 1 25  ? 22.102  39.679  70.639 1.00 57.17  ? 227 ASN D O   1 
ATOM   9461  C CB  . ASN D 1 25  ? 22.012  41.061  73.796 1.00 56.51  ? 227 ASN D CB  1 
ATOM   9462  C CG  . ASN D 1 25  ? 21.147  41.634  74.896 1.00 57.23  ? 227 ASN D CG  1 
ATOM   9463  O OD1 . ASN D 1 25  ? 20.231  42.412  74.639 1.00 57.91  ? 227 ASN D OD1 1 
ATOM   9464  N ND2 . ASN D 1 25  ? 21.434  41.251  76.133 1.00 57.66  ? 227 ASN D ND2 1 
ATOM   9465  N N   . TRP D 1 26  ? 23.380  41.434  71.221 1.00 52.16  ? 228 TRP D N   1 
ATOM   9466  C CA  . TRP D 1 26  ? 24.435  41.132  70.264 1.00 52.68  ? 228 TRP D CA  1 
ATOM   9467  C C   . TRP D 1 26  ? 25.518  40.321  70.966 1.00 54.17  ? 228 TRP D C   1 
ATOM   9468  O O   . TRP D 1 26  ? 26.220  40.843  71.839 1.00 54.59  ? 228 TRP D O   1 
ATOM   9469  C CB  . TRP D 1 26  ? 25.033  42.413  69.690 1.00 49.08  ? 228 TRP D CB  1 
ATOM   9470  C CG  . TRP D 1 26  ? 26.066  42.159  68.650 1.00 48.36  ? 228 TRP D CG  1 
ATOM   9471  C CD1 . TRP D 1 26  ? 27.408  42.054  68.841 1.00 47.76  ? 228 TRP D CD1 1 
ATOM   9472  C CD2 . TRP D 1 26  ? 25.849  42.035  67.242 1.00 47.82  ? 228 TRP D CD2 1 
ATOM   9473  N NE1 . TRP D 1 26  ? 28.040  41.837  67.644 1.00 48.14  ? 228 TRP D NE1 1 
ATOM   9474  C CE2 . TRP D 1 26  ? 27.104  41.827  66.645 1.00 48.29  ? 228 TRP D CE2 1 
ATOM   9475  C CE3 . TRP D 1 26  ? 24.715  42.076  66.429 1.00 47.62  ? 228 TRP D CE3 1 
ATOM   9476  C CZ2 . TRP D 1 26  ? 27.255  41.655  65.275 1.00 48.67  ? 228 TRP D CZ2 1 
ATOM   9477  C CZ3 . TRP D 1 26  ? 24.868  41.906  65.073 1.00 48.42  ? 228 TRP D CZ3 1 
ATOM   9478  C CH2 . TRP D 1 26  ? 26.127  41.700  64.509 1.00 48.63  ? 228 TRP D CH2 1 
ATOM   9479  N N   . HIS D 1 27  ? 25.660  39.055  70.582 1.00 51.44  ? 229 HIS D N   1 
ATOM   9480  C CA  . HIS D 1 27  ? 26.658  38.165  71.166 1.00 54.43  ? 229 HIS D CA  1 
ATOM   9481  C C   . HIS D 1 27  ? 27.664  37.785  70.089 1.00 56.05  ? 229 HIS D C   1 
ATOM   9482  O O   . HIS D 1 27  ? 27.328  37.052  69.154 1.00 57.15  ? 229 HIS D O   1 
ATOM   9483  C CB  . HIS D 1 27  ? 25.999  36.920  71.756 1.00 54.90  ? 229 HIS D CB  1 
ATOM   9484  C CG  . HIS D 1 27  ? 25.087  37.200  72.909 1.00 59.06  ? 229 HIS D CG  1 
ATOM   9485  N ND1 . HIS D 1 27  ? 23.779  37.602  72.744 1.00 59.90  ? 229 HIS D ND1 1 
ATOM   9486  C CD2 . HIS D 1 27  ? 25.292  37.126  74.245 1.00 60.74  ? 229 HIS D CD2 1 
ATOM   9487  C CE1 . HIS D 1 27  ? 23.219  37.767  73.930 1.00 61.40  ? 229 HIS D CE1 1 
ATOM   9488  N NE2 . HIS D 1 27  ? 24.116  37.485  74.857 1.00 62.86  ? 229 HIS D NE2 1 
ATOM   9489  N N   . CYS D 1 28  ? 28.909  38.222  70.218 1.00 56.17  ? 230 CYS D N   1 
ATOM   9490  C CA  . CYS D 1 28  ? 29.907  37.869  69.210 1.00 58.96  ? 230 CYS D CA  1 
ATOM   9491  C C   . CYS D 1 28  ? 31.313  37.611  69.739 1.00 60.38  ? 230 CYS D C   1 
ATOM   9492  O O   . CYS D 1 28  ? 32.259  38.245  69.283 1.00 61.77  ? 230 CYS D O   1 
ATOM   9493  C CB  . CYS D 1 28  ? 29.986  38.950  68.135 1.00 57.38  ? 230 CYS D CB  1 
ATOM   9494  S SG  . CYS D 1 28  ? 28.874  38.723  66.736 1.00 60.43  ? 230 CYS D SG  1 
ATOM   9495  N N   . ASP D 1 29  ? 31.468  36.676  70.669 1.00 58.72  ? 231 ASP D N   1 
ATOM   9496  C CA  . ASP D 1 29  ? 32.796  36.382  71.212 1.00 60.92  ? 231 ASP D CA  1 
ATOM   9497  C C   . ASP D 1 29  ? 33.114  34.895  71.308 1.00 58.82  ? 231 ASP D C   1 
ATOM   9498  O O   . ASP D 1 29  ? 32.218  34.065  71.365 1.00 59.17  ? 231 ASP D O   1 
ATOM   9499  C CB  . ASP D 1 29  ? 33.002  37.057  72.573 1.00 60.36  ? 231 ASP D CB  1 
ATOM   9500  C CG  . ASP D 1 29  ? 31.748  37.061  73.422 1.00 64.49  ? 231 ASP D CG  1 
ATOM   9501  O OD1 . ASP D 1 29  ? 30.642  37.102  72.847 1.00 66.78  ? 231 ASP D OD1 1 
ATOM   9502  O OD2 . ASP D 1 29  ? 31.870  37.035  74.664 1.00 66.76  ? 231 ASP D OD2 1 
ATOM   9503  N N   . SER D 1 30  ? 34.403  34.571  71.307 1.00 63.52  ? 232 SER D N   1 
ATOM   9504  C CA  . SER D 1 30  ? 34.856  33.192  71.417 1.00 62.68  ? 232 SER D CA  1 
ATOM   9505  C C   . SER D 1 30  ? 35.628  33.004  72.719 1.00 62.20  ? 232 SER D C   1 
ATOM   9506  O O   . SER D 1 30  ? 36.553  33.758  73.009 1.00 62.50  ? 232 SER D O   1 
ATOM   9507  C CB  . SER D 1 30  ? 35.730  32.811  70.225 1.00 60.34  ? 232 SER D CB  1 
ATOM   9508  O OG  . SER D 1 30  ? 36.976  33.477  70.273 1.00 60.39  ? 232 SER D OG  1 
ATOM   9509  N N   . GLN D 1 31  ? 35.260  31.985  73.491 1.00 60.83  ? 233 GLN D N   1 
ATOM   9510  C CA  . GLN D 1 31  ? 35.896  31.726  74.781 1.00 60.48  ? 233 GLN D CA  1 
ATOM   9511  C C   . GLN D 1 31  ? 36.654  30.410  74.825 1.00 58.75  ? 233 GLN D C   1 
ATOM   9512  O O   . GLN D 1 31  ? 36.112  29.371  74.480 1.00 58.52  ? 233 GLN D O   1 
ATOM   9513  C CB  . GLN D 1 31  ? 34.835  31.701  75.878 1.00 57.92  ? 233 GLN D CB  1 
ATOM   9514  C CG  . GLN D 1 31  ? 33.588  32.503  75.554 1.00 65.42  ? 233 GLN D CG  1 
ATOM   9515  C CD  . GLN D 1 31  ? 32.378  32.021  76.325 1.00 69.53  ? 233 GLN D CD  1 
ATOM   9516  O OE1 . GLN D 1 31  ? 32.508  31.282  77.299 1.00 71.29  ? 233 GLN D OE1 1 
ATOM   9517  N NE2 . GLN D 1 31  ? 31.193  32.432  75.891 1.00 70.80  ? 233 GLN D NE2 1 
ATOM   9518  N N   . TRP D 1 32  ? 37.900  30.452  75.285 1.00 61.83  ? 234 TRP D N   1 
ATOM   9519  C CA  . TRP D 1 32  ? 38.715  29.247  75.379 1.00 61.39  ? 234 TRP D CA  1 
ATOM   9520  C C   . TRP D 1 32  ? 38.872  28.778  76.818 1.00 62.95  ? 234 TRP D C   1 
ATOM   9521  O O   . TRP D 1 32  ? 39.447  29.483  77.643 1.00 63.14  ? 234 TRP D O   1 
ATOM   9522  C CB  . TRP D 1 32  ? 40.108  29.529  74.821 1.00 61.00  ? 234 TRP D CB  1 
ATOM   9523  C CG  . TRP D 1 32  ? 40.135  29.777  73.362 1.00 59.23  ? 234 TRP D CG  1 
ATOM   9524  C CD1 . TRP D 1 32  ? 39.663  30.872  72.708 1.00 58.64  ? 234 TRP D CD1 1 
ATOM   9525  C CD2 . TRP D 1 32  ? 40.673  28.911  72.362 1.00 57.80  ? 234 TRP D CD2 1 
ATOM   9526  N NE1 . TRP D 1 32  ? 39.867  30.740  71.358 1.00 56.29  ? 234 TRP D NE1 1 
ATOM   9527  C CE2 . TRP D 1 32  ? 40.488  29.543  71.121 1.00 56.73  ? 234 TRP D CE2 1 
ATOM   9528  C CE3 . TRP D 1 32  ? 41.292  27.660  72.395 1.00 55.87  ? 234 TRP D CE3 1 
ATOM   9529  C CZ2 . TRP D 1 32  ? 40.898  28.966  69.924 1.00 55.94  ? 234 TRP D CZ2 1 
ATOM   9530  C CZ3 . TRP D 1 32  ? 41.699  27.092  71.208 1.00 55.82  ? 234 TRP D CZ3 1 
ATOM   9531  C CH2 . TRP D 1 32  ? 41.501  27.743  69.990 1.00 56.22  ? 234 TRP D CH2 1 
ATOM   9532  N N   . LEU D 1 33  ? 38.365  27.587  77.120 1.00 63.68  ? 235 LEU D N   1 
ATOM   9533  C CA  . LEU D 1 33  ? 38.500  27.028  78.459 1.00 65.75  ? 235 LEU D CA  1 
ATOM   9534  C C   . LEU D 1 33  ? 39.008  25.600  78.360 1.00 66.75  ? 235 LEU D C   1 
ATOM   9535  O O   . LEU D 1 33  ? 38.312  24.737  77.847 1.00 67.79  ? 235 LEU D O   1 
ATOM   9536  C CB  . LEU D 1 33  ? 37.147  27.033  79.170 1.00 67.05  ? 235 LEU D CB  1 
ATOM   9537  C CG  . LEU D 1 33  ? 36.159  28.140  78.798 1.00 69.05  ? 235 LEU D CG  1 
ATOM   9538  C CD1 . LEU D 1 33  ? 35.629  27.933  77.388 1.00 69.44  ? 235 LEU D CD1 1 
ATOM   9539  C CD2 . LEU D 1 33  ? 35.009  28.181  79.789 1.00 68.91  ? 235 LEU D CD2 1 
ATOM   9540  N N   . GLY D 1 34  ? 40.183  25.322  78.907 1.00 65.28  ? 236 GLY D N   1 
ATOM   9541  C CA  . GLY D 1 34  ? 40.712  23.974  78.836 1.00 66.07  ? 236 GLY D CA  1 
ATOM   9542  C C   . GLY D 1 34  ? 40.831  23.516  77.395 1.00 66.79  ? 236 GLY D C   1 
ATOM   9543  O O   . GLY D 1 34  ? 41.413  24.201  76.557 1.00 67.80  ? 236 GLY D O   1 
ATOM   9544  N N   . ASP D 1 35  ? 40.269  22.346  77.113 1.00 64.37  ? 237 ASP D N   1 
ATOM   9545  C CA  . ASP D 1 35  ? 40.287  21.771  75.773 1.00 64.74  ? 237 ASP D CA  1 
ATOM   9546  C C   . ASP D 1 35  ? 38.988  22.029  75.014 1.00 62.03  ? 237 ASP D C   1 
ATOM   9547  O O   . ASP D 1 35  ? 38.756  21.449  73.958 1.00 61.01  ? 237 ASP D O   1 
ATOM   9548  C CB  . ASP D 1 35  ? 40.553  20.271  75.834 1.00 60.99  ? 237 ASP D CB  1 
ATOM   9549  C CG  . ASP D 1 35  ? 39.355  19.498  76.305 1.00 67.84  ? 237 ASP D CG  1 
ATOM   9550  O OD1 . ASP D 1 35  ? 38.506  20.103  76.986 1.00 71.13  ? 237 ASP D OD1 1 
ATOM   9551  O OD2 . ASP D 1 35  ? 39.258  18.293  75.993 1.00 70.01  ? 237 ASP D OD2 1 
ATOM   9552  N N   . ARG D 1 36  ? 38.129  22.876  75.567 1.00 63.72  ? 238 ARG D N   1 
ATOM   9553  C CA  . ARG D 1 36  ? 36.854  23.189  74.933 1.00 62.06  ? 238 ARG D CA  1 
ATOM   9554  C C   . ARG D 1 36  ? 36.774  24.636  74.458 1.00 58.26  ? 238 ARG D C   1 
ATOM   9555  O O   . ARG D 1 36  ? 37.105  25.555  75.189 1.00 57.70  ? 238 ARG D O   1 
ATOM   9556  C CB  . ARG D 1 36  ? 35.704  22.886  75.892 1.00 57.10  ? 238 ARG D CB  1 
ATOM   9557  C CG  . ARG D 1 36  ? 34.343  23.308  75.372 1.00 67.23  ? 238 ARG D CG  1 
ATOM   9558  C CD  . ARG D 1 36  ? 33.222  22.555  76.068 1.00 75.16  ? 238 ARG D CD  1 
ATOM   9559  N NE  . ARG D 1 36  ? 33.192  22.792  77.508 1.00 83.47  ? 238 ARG D NE  1 
ATOM   9560  C CZ  . ARG D 1 36  ? 32.747  23.909  78.070 1.00 86.59  ? 238 ARG D CZ  1 
ATOM   9561  N NH1 . ARG D 1 36  ? 32.308  24.902  77.311 1.00 88.41  ? 238 ARG D NH1 1 
ATOM   9562  N NH2 . ARG D 1 36  ? 32.748  24.039  79.390 1.00 86.37  ? 238 ARG D NH2 1 
ATOM   9563  N N   . VAL D 1 37  ? 36.341  24.838  73.222 1.00 58.83  ? 239 VAL D N   1 
ATOM   9564  C CA  . VAL D 1 37  ? 36.225  26.188  72.681 1.00 55.47  ? 239 VAL D CA  1 
ATOM   9565  C C   . VAL D 1 37  ? 34.785  26.503  72.305 1.00 54.17  ? 239 VAL D C   1 
ATOM   9566  O O   . VAL D 1 37  ? 34.124  25.709  71.654 1.00 53.03  ? 239 VAL D O   1 
ATOM   9567  C CB  . VAL D 1 37  ? 37.103  26.365  71.434 1.00 51.98  ? 239 VAL D CB  1 
ATOM   9568  C CG1 . VAL D 1 37  ? 37.554  27.808  71.300 1.00 49.46  ? 239 VAL D CG1 1 
ATOM   9569  C CG2 . VAL D 1 37  ? 38.299  25.440  71.516 1.00 54.68  ? 239 VAL D CG2 1 
ATOM   9570  N N   . ILE D 1 38  ? 34.296  27.659  72.727 1.00 52.98  ? 240 ILE D N   1 
ATOM   9571  C CA  . ILE D 1 38  ? 32.941  28.061  72.398 1.00 51.80  ? 240 ILE D CA  1 
ATOM   9572  C C   . ILE D 1 38  ? 33.018  29.261  71.479 1.00 52.53  ? 240 ILE D C   1 
ATOM   9573  O O   . ILE D 1 38  ? 33.690  30.224  71.795 1.00 53.33  ? 240 ILE D O   1 
ATOM   9574  C CB  . ILE D 1 38  ? 32.157  28.480  73.643 1.00 53.74  ? 240 ILE D CB  1 
ATOM   9575  C CG1 . ILE D 1 38  ? 32.280  27.423  74.734 1.00 53.51  ? 240 ILE D CG1 1 
ATOM   9576  C CG2 . ILE D 1 38  ? 30.697  28.710  73.291 1.00 51.54  ? 240 ILE D CG2 1 
ATOM   9577  C CD1 . ILE D 1 38  ? 31.406  27.703  75.933 1.00 55.58  ? 240 ILE D CD1 1 
ATOM   9578  N N   . THR D 1 39  ? 32.330  29.205  70.347 1.00 50.80  ? 241 THR D N   1 
ATOM   9579  C CA  . THR D 1 39  ? 32.345  30.308  69.397 1.00 51.27  ? 241 THR D CA  1 
ATOM   9580  C C   . THR D 1 39  ? 30.957  30.883  69.219 1.00 51.43  ? 241 THR D C   1 
ATOM   9581  O O   . THR D 1 39  ? 29.998  30.148  69.050 1.00 51.73  ? 241 THR D O   1 
ATOM   9582  C CB  . THR D 1 39  ? 32.830  29.859  68.015 1.00 49.43  ? 241 THR D CB  1 
ATOM   9583  O OG1 . THR D 1 39  ? 31.877  28.948  67.453 1.00 50.65  ? 241 THR D OG1 1 
ATOM   9584  C CG2 . THR D 1 39  ? 34.182  29.192  68.115 1.00 47.74  ? 241 THR D CG2 1 
ATOM   9585  N N   . THR D 1 40  ? 30.848  32.202  69.257 1.00 51.50  ? 242 THR D N   1 
ATOM   9586  C CA  . THR D 1 40  ? 29.558  32.852  69.089 1.00 53.21  ? 242 THR D CA  1 
ATOM   9587  C C   . THR D 1 40  ? 29.596  33.823  67.919 1.00 51.67  ? 242 THR D C   1 
ATOM   9588  O O   . THR D 1 40  ? 30.428  34.724  67.875 1.00 50.25  ? 242 THR D O   1 
ATOM   9589  C CB  . THR D 1 40  ? 29.137  33.595  70.366 1.00 51.61  ? 242 THR D CB  1 
ATOM   9590  O OG1 . THR D 1 40  ? 29.265  32.717  71.490 1.00 58.09  ? 242 THR D OG1 1 
ATOM   9591  C CG2 . THR D 1 40  ? 27.703  34.054  70.260 1.00 53.76  ? 242 THR D CG2 1 
ATOM   9592  N N   . SER D 1 41  ? 28.699  33.619  66.963 1.00 43.60  ? 243 SER D N   1 
ATOM   9593  C CA  . SER D 1 41  ? 28.618  34.473  65.790 1.00 43.72  ? 243 SER D CA  1 
ATOM   9594  C C   . SER D 1 41  ? 27.232  35.085  65.713 1.00 43.07  ? 243 SER D C   1 
ATOM   9595  O O   . SER D 1 41  ? 26.237  34.405  65.969 1.00 44.02  ? 243 SER D O   1 
ATOM   9596  C CB  . SER D 1 41  ? 28.905  33.689  64.511 1.00 41.61  ? 243 SER D CB  1 
ATOM   9597  O OG  . SER D 1 41  ? 30.227  33.189  64.508 1.00 47.30  ? 243 SER D OG  1 
ATOM   9598  N N   . THR D 1 42  ? 27.166  36.363  65.356 1.00 45.01  ? 244 THR D N   1 
ATOM   9599  C CA  . THR D 1 42  ? 25.901  37.069  65.222 1.00 43.52  ? 244 THR D CA  1 
ATOM   9600  C C   . THR D 1 42  ? 25.943  37.957  63.986 1.00 43.81  ? 244 THR D C   1 
ATOM   9601  O O   . THR D 1 42  ? 26.898  38.714  63.790 1.00 45.58  ? 244 THR D O   1 
ATOM   9602  C CB  . THR D 1 42  ? 25.598  37.901  66.472 1.00 43.71  ? 244 THR D CB  1 
ATOM   9603  O OG1 . THR D 1 42  ? 25.593  37.047  67.620 1.00 43.55  ? 244 THR D OG1 1 
ATOM   9604  C CG2 . THR D 1 42  ? 24.238  38.546  66.357 1.00 42.93  ? 244 THR D CG2 1 
ATOM   9605  N N   . ARG D 1 43  ? 24.911  37.855  63.147 1.00 42.32  ? 245 ARG D N   1 
ATOM   9606  C CA  . ARG D 1 43  ? 24.853  38.595  61.895 1.00 41.56  ? 245 ARG D CA  1 
ATOM   9607  C C   . ARG D 1 43  ? 23.475  39.221  61.738 1.00 41.17  ? 245 ARG D C   1 
ATOM   9608  O O   . ARG D 1 43  ? 22.540  38.907  62.475 1.00 41.37  ? 245 ARG D O   1 
ATOM   9609  C CB  . ARG D 1 43  ? 25.140  37.701  60.686 1.00 38.47  ? 245 ARG D CB  1 
ATOM   9610  C CG  . ARG D 1 43  ? 26.460  36.962  60.716 1.00 40.62  ? 245 ARG D CG  1 
ATOM   9611  C CD  . ARG D 1 43  ? 27.647  37.881  60.536 1.00 41.50  ? 245 ARG D CD  1 
ATOM   9612  N NE  . ARG D 1 43  ? 28.887  37.120  60.440 1.00 45.88  ? 245 ARG D NE  1 
ATOM   9613  C CZ  . ARG D 1 43  ? 29.628  36.764  61.482 1.00 46.54  ? 245 ARG D CZ  1 
ATOM   9614  N NH1 . ARG D 1 43  ? 30.741  36.071  61.301 1.00 47.44  ? 245 ARG D NH1 1 
ATOM   9615  N NH2 . ARG D 1 43  ? 29.249  37.085  62.709 1.00 47.47  ? 245 ARG D NH2 1 
ATOM   9616  N N   . THR D 1 44  ? 23.360  40.117  60.761 1.00 42.03  ? 246 THR D N   1 
ATOM   9617  C CA  . THR D 1 44  ? 22.097  40.751  60.403 1.00 42.60  ? 246 THR D CA  1 
ATOM   9618  C C   . THR D 1 44  ? 21.672  40.287  59.017 1.00 43.33  ? 246 THR D C   1 
ATOM   9619  O O   . THR D 1 44  ? 22.364  40.557  58.031 1.00 43.31  ? 246 THR D O   1 
ATOM   9620  C CB  . THR D 1 44  ? 22.215  42.276  60.426 1.00 42.78  ? 246 THR D CB  1 
ATOM   9621  O OG1 . THR D 1 44  ? 22.574  42.713  61.741 1.00 44.28  ? 246 THR D OG1 1 
ATOM   9622  C CG2 . THR D 1 44  ? 20.892  42.909  60.038 1.00 42.64  ? 246 THR D CG2 1 
ATOM   9623  N N   . TRP D 1 45  ? 20.525  39.616  58.941 1.00 40.28  ? 247 TRP D N   1 
ATOM   9624  C CA  . TRP D 1 45  ? 20.059  38.979  57.719 1.00 39.94  ? 247 TRP D CA  1 
ATOM   9625  C C   . TRP D 1 45  ? 18.988  39.819  57.038 1.00 41.18  ? 247 TRP D C   1 
ATOM   9626  O O   . TRP D 1 45  ? 18.195  40.503  57.689 1.00 40.90  ? 247 TRP D O   1 
ATOM   9627  C CB  . TRP D 1 45  ? 19.498  37.582  57.999 1.00 40.13  ? 247 TRP D CB  1 
ATOM   9628  C CG  . TRP D 1 45  ? 18.393  37.553  59.020 1.00 40.40  ? 247 TRP D CG  1 
ATOM   9629  C CD1 . TRP D 1 45  ? 18.532  37.388  60.361 1.00 40.13  ? 247 TRP D CD1 1 
ATOM   9630  C CD2 . TRP D 1 45  ? 16.987  37.700  58.781 1.00 40.53  ? 247 TRP D CD2 1 
ATOM   9631  N NE1 . TRP D 1 45  ? 17.306  37.406  60.974 1.00 38.81  ? 247 TRP D NE1 1 
ATOM   9632  C CE2 . TRP D 1 45  ? 16.341  37.603  60.024 1.00 39.17  ? 247 TRP D CE2 1 
ATOM   9633  C CE3 . TRP D 1 45  ? 16.214  37.906  57.638 1.00 41.40  ? 247 TRP D CE3 1 
ATOM   9634  C CZ2 . TRP D 1 45  ? 14.962  37.702  60.156 1.00 39.07  ? 247 TRP D CZ2 1 
ATOM   9635  C CZ3 . TRP D 1 45  ? 14.847  37.997  57.772 1.00 40.87  ? 247 TRP D CZ3 1 
ATOM   9636  C CH2 . TRP D 1 45  ? 14.234  37.898  59.020 1.00 39.75  ? 247 TRP D CH2 1 
ATOM   9637  N N   . ALA D 1 46  ? 18.973  39.756  55.706 1.00 38.15  ? 248 ALA D N   1 
ATOM   9638  C CA  . ALA D 1 46  ? 17.954  40.406  54.892 1.00 38.73  ? 248 ALA D CA  1 
ATOM   9639  C C   . ALA D 1 46  ? 17.299  39.367  53.994 1.00 38.78  ? 248 ALA D C   1 
ATOM   9640  O O   . ALA D 1 46  ? 17.949  38.823  53.097 1.00 39.33  ? 248 ALA D O   1 
ATOM   9641  C CB  . ALA D 1 46  ? 18.556  41.533  54.047 1.00 35.97  ? 248 ALA D CB  1 
ATOM   9642  N N   . LEU D 1 47  ? 16.018  39.104  54.226 1.00 35.99  ? 249 LEU D N   1 
ATOM   9643  C CA  . LEU D 1 47  ? 15.287  38.065  53.498 1.00 35.41  ? 249 LEU D CA  1 
ATOM   9644  C C   . LEU D 1 47  ? 14.212  38.669  52.611 1.00 36.25  ? 249 LEU D C   1 
ATOM   9645  O O   . LEU D 1 47  ? 13.283  39.321  53.126 1.00 36.71  ? 249 LEU D O   1 
ATOM   9646  C CB  . LEU D 1 47  ? 14.657  37.072  54.471 1.00 36.88  ? 249 LEU D CB  1 
ATOM   9647  C CG  . LEU D 1 47  ? 13.783  35.995  53.832 1.00 36.17  ? 249 LEU D CG  1 
ATOM   9648  C CD1 . LEU D 1 47  ? 14.612  35.106  52.933 1.00 36.17  ? 249 LEU D CD1 1 
ATOM   9649  C CD2 . LEU D 1 47  ? 13.078  35.180  54.893 1.00 37.08  ? 249 LEU D CD2 1 
ATOM   9650  N N   . PRO D 1 48  ? 14.278  38.482  51.294 1.00 34.13  ? 250 PRO D N   1 
ATOM   9651  C CA  . PRO D 1 48  ? 13.204  38.969  50.423 1.00 34.95  ? 250 PRO D CA  1 
ATOM   9652  C C   . PRO D 1 48  ? 12.116  37.934  50.210 1.00 36.13  ? 250 PRO D C   1 
ATOM   9653  O O   . PRO D 1 48  ? 12.159  36.840  50.780 1.00 36.69  ? 250 PRO D O   1 
ATOM   9654  C CB  . PRO D 1 48  ? 13.935  39.266  49.113 1.00 33.43  ? 250 PRO D CB  1 
ATOM   9655  C CG  . PRO D 1 48  ? 15.022  38.257  49.087 1.00 32.41  ? 250 PRO D CG  1 
ATOM   9656  C CD  . PRO D 1 48  ? 15.428  37.990  50.519 1.00 32.36  ? 250 PRO D CD  1 
ATOM   9657  N N   . THR D 1 49  ? 11.134  38.278  49.386 1.00 32.55  ? 251 THR D N   1 
ATOM   9658  C CA  . THR D 1 49  ? 10.140  37.325  48.921 1.00 32.88  ? 251 THR D CA  1 
ATOM   9659  C C   . THR D 1 49  ? 10.667  36.648  47.664 1.00 33.00  ? 251 THR D C   1 
ATOM   9660  O O   . THR D 1 49  ? 11.149  37.321  46.748 1.00 32.66  ? 251 THR D O   1 
ATOM   9661  C CB  . THR D 1 49  ? 8.815   38.027  48.633 1.00 32.56  ? 251 THR D CB  1 
ATOM   9662  O OG1 . THR D 1 49  ? 8.299   38.595  49.843 1.00 33.74  ? 251 THR D OG1 1 
ATOM   9663  C CG2 . THR D 1 49  ? 7.809   37.052  48.058 1.00 30.97  ? 251 THR D CG2 1 
ATOM   9664  N N   . TYR D 1 50  ? 10.591  35.322  47.625 1.00 26.07  ? 252 TYR D N   1 
ATOM   9665  C CA  . TYR D 1 50  ? 11.094  34.549  46.499 1.00 27.06  ? 252 TYR D CA  1 
ATOM   9666  C C   . TYR D 1 50  ? 9.940   33.919  45.734 1.00 28.38  ? 252 TYR D C   1 
ATOM   9667  O O   . TYR D 1 50  ? 8.992   33.412  46.340 1.00 29.78  ? 252 TYR D O   1 
ATOM   9668  C CB  . TYR D 1 50  ? 12.066  33.467  46.964 1.00 29.10  ? 252 TYR D CB  1 
ATOM   9669  C CG  . TYR D 1 50  ? 13.348  34.002  47.550 1.00 27.62  ? 252 TYR D CG  1 
ATOM   9670  C CD1 . TYR D 1 50  ? 14.380  34.433  46.728 1.00 27.43  ? 252 TYR D CD1 1 
ATOM   9671  C CD2 . TYR D 1 50  ? 13.549  34.027  48.919 1.00 27.02  ? 252 TYR D CD2 1 
ATOM   9672  C CE1 . TYR D 1 50  ? 15.558  34.912  47.253 1.00 26.41  ? 252 TYR D CE1 1 
ATOM   9673  C CE2 . TYR D 1 50  ? 14.729  34.495  49.453 1.00 26.98  ? 252 TYR D CE2 1 
ATOM   9674  C CZ  . TYR D 1 50  ? 15.728  34.936  48.615 1.00 27.17  ? 252 TYR D CZ  1 
ATOM   9675  O OH  . TYR D 1 50  ? 16.903  35.403  49.144 1.00 29.19  ? 252 TYR D OH  1 
ATOM   9676  N N   . ASN D 1 51  ? 10.027  33.966  44.404 1.00 24.34  ? 253 ASN D N   1 
ATOM   9677  C CA  . ASN D 1 51  ? 9.057   33.338  43.502 1.00 26.19  ? 253 ASN D CA  1 
ATOM   9678  C C   . ASN D 1 51  ? 7.647   33.875  43.703 1.00 27.50  ? 253 ASN D C   1 
ATOM   9679  O O   . ASN D 1 51  ? 6.673   33.223  43.328 1.00 28.37  ? 253 ASN D O   1 
ATOM   9680  C CB  . ASN D 1 51  ? 9.048   31.817  43.651 1.00 24.21  ? 253 ASN D CB  1 
ATOM   9681  C CG  . ASN D 1 51  ? 10.310  31.174  43.151 1.00 24.72  ? 253 ASN D CG  1 
ATOM   9682  O OD1 . ASN D 1 51  ? 11.063  31.765  42.382 1.00 26.29  ? 253 ASN D OD1 1 
ATOM   9683  N ND2 . ASN D 1 51  ? 10.533  29.935  43.557 1.00 23.02  ? 253 ASN D ND2 1 
ATOM   9684  N N   . ASN D 1 52  ? 7.532   35.069  44.277 1.00 28.40  ? 254 ASN D N   1 
ATOM   9685  C CA  . ASN D 1 52  ? 6.239   35.679  44.564 1.00 30.67  ? 254 ASN D CA  1 
ATOM   9686  C C   . ASN D 1 52  ? 5.337   34.720  45.337 1.00 30.16  ? 254 ASN D C   1 
ATOM   9687  O O   . ASN D 1 52  ? 4.127   34.658  45.114 1.00 29.77  ? 254 ASN D O   1 
ATOM   9688  C CB  . ASN D 1 52  ? 5.565   36.149  43.276 1.00 28.03  ? 254 ASN D CB  1 
ATOM   9689  C CG  . ASN D 1 52  ? 6.323   37.275  42.605 1.00 33.60  ? 254 ASN D CG  1 
ATOM   9690  O OD1 . ASN D 1 52  ? 6.269   38.424  43.043 1.00 36.96  ? 254 ASN D OD1 1 
ATOM   9691  N ND2 . ASN D 1 52  ? 7.036   36.951  41.533 1.00 36.20  ? 254 ASN D ND2 1 
ATOM   9692  N N   . HIS D 1 53  ? 5.942   33.970  46.262 1.00 29.67  ? 255 HIS D N   1 
ATOM   9693  C CA  . HIS D 1 53  ? 5.240   32.992  47.100 1.00 29.73  ? 255 HIS D CA  1 
ATOM   9694  C C   . HIS D 1 53  ? 4.667   31.838  46.278 1.00 28.51  ? 255 HIS D C   1 
ATOM   9695  O O   . HIS D 1 53  ? 3.515   31.439  46.457 1.00 29.91  ? 255 HIS D O   1 
ATOM   9696  C CB  . HIS D 1 53  ? 4.138   33.654  47.927 1.00 30.35  ? 255 HIS D CB  1 
ATOM   9697  C CG  . HIS D 1 53  ? 4.627   34.745  48.824 1.00 33.57  ? 255 HIS D CG  1 
ATOM   9698  N ND1 . HIS D 1 53  ? 5.429   34.503  49.918 1.00 36.38  ? 255 HIS D ND1 1 
ATOM   9699  C CD2 . HIS D 1 53  ? 4.419   36.082  48.796 1.00 33.10  ? 255 HIS D CD2 1 
ATOM   9700  C CE1 . HIS D 1 53  ? 5.699   35.646  50.522 1.00 36.70  ? 255 HIS D CE1 1 
ATOM   9701  N NE2 . HIS D 1 53  ? 5.097   36.619  49.862 1.00 35.29  ? 255 HIS D NE2 1 
ATOM   9702  N N   . LEU D 1 54  ? 5.474   31.293  45.372 1.00 26.71  ? 256 LEU D N   1 
ATOM   9703  C CA  . LEU D 1 54  ? 5.070   30.171  44.538 1.00 23.31  ? 256 LEU D CA  1 
ATOM   9704  C C   . LEU D 1 54  ? 6.153   29.101  44.525 1.00 23.27  ? 256 LEU D C   1 
ATOM   9705  O O   . LEU D 1 54  ? 7.349   29.394  44.532 1.00 24.26  ? 256 LEU D O   1 
ATOM   9706  C CB  . LEU D 1 54  ? 4.780   30.612  43.095 1.00 26.74  ? 256 LEU D CB  1 
ATOM   9707  C CG  . LEU D 1 54  ? 3.384   31.068  42.668 1.00 24.20  ? 256 LEU D CG  1 
ATOM   9708  C CD1 . LEU D 1 54  ? 2.932   32.301  43.402 1.00 22.53  ? 256 LEU D CD1 1 
ATOM   9709  C CD2 . LEU D 1 54  ? 3.389   31.331  41.178 1.00 23.07  ? 256 LEU D CD2 1 
ATOM   9710  N N   . TYR D 1 55  ? 5.715   27.848  44.516 1.00 21.05  ? 257 TYR D N   1 
ATOM   9711  C CA  . TYR D 1 55  ? 6.558   26.725  44.135 1.00 20.48  ? 257 TYR D CA  1 
ATOM   9712  C C   . TYR D 1 55  ? 6.584   26.647  42.620 1.00 20.58  ? 257 TYR D C   1 
ATOM   9713  O O   . TYR D 1 55  ? 5.534   26.515  41.987 1.00 21.84  ? 257 TYR D O   1 
ATOM   9714  C CB  . TYR D 1 55  ? 6.032   25.409  44.704 1.00 19.42  ? 257 TYR D CB  1 
ATOM   9715  C CG  . TYR D 1 55  ? 6.169   25.255  46.191 1.00 20.36  ? 257 TYR D CG  1 
ATOM   9716  C CD1 . TYR D 1 55  ? 7.248   24.585  46.739 1.00 20.38  ? 257 TYR D CD1 1 
ATOM   9717  C CD2 . TYR D 1 55  ? 5.232   25.802  47.048 1.00 20.35  ? 257 TYR D CD2 1 
ATOM   9718  C CE1 . TYR D 1 55  ? 7.374   24.441  48.097 1.00 21.48  ? 257 TYR D CE1 1 
ATOM   9719  C CE2 . TYR D 1 55  ? 5.352   25.670  48.403 1.00 22.04  ? 257 TYR D CE2 1 
ATOM   9720  C CZ  . TYR D 1 55  ? 6.423   24.990  48.923 1.00 22.61  ? 257 TYR D CZ  1 
ATOM   9721  O OH  . TYR D 1 55  ? 6.541   24.860  50.282 1.00 24.85  ? 257 TYR D OH  1 
ATOM   9722  N N   . LYS D 1 56  ? 7.774   26.728  42.041 1.00 20.02  ? 258 LYS D N   1 
ATOM   9723  C CA  . LYS D 1 56  ? 7.912   26.659  40.597 1.00 19.88  ? 258 LYS D CA  1 
ATOM   9724  C C   . LYS D 1 56  ? 8.744   25.451  40.208 1.00 19.22  ? 258 LYS D C   1 
ATOM   9725  O O   . LYS D 1 56  ? 9.794   25.183  40.796 1.00 20.00  ? 258 LYS D O   1 
ATOM   9726  C CB  . LYS D 1 56  ? 8.540   27.933  40.024 1.00 20.30  ? 258 LYS D CB  1 
ATOM   9727  C CG  . LYS D 1 56  ? 7.638   29.147  40.130 1.00 23.75  ? 258 LYS D CG  1 
ATOM   9728  C CD  . LYS D 1 56  ? 8.140   30.303  39.284 1.00 24.74  ? 258 LYS D CD  1 
ATOM   9729  C CE  . LYS D 1 56  ? 9.473   30.823  39.772 1.00 26.80  ? 258 LYS D CE  1 
ATOM   9730  N NZ  . LYS D 1 56  ? 9.887   32.035  39.017 1.00 29.63  ? 258 LYS D NZ  1 
ATOM   9731  N N   . GLN D 1 57  ? 8.245   24.712  39.229 1.00 19.14  ? 259 GLN D N   1 
ATOM   9732  C CA  . GLN D 1 57  ? 9.029   23.693  38.557 1.00 18.90  ? 259 GLN D CA  1 
ATOM   9733  C C   . GLN D 1 57  ? 10.161  24.327  37.765 1.00 19.49  ? 259 GLN D C   1 
ATOM   9734  O O   . GLN D 1 57  ? 9.949   25.253  36.980 1.00 19.64  ? 259 GLN D O   1 
ATOM   9735  C CB  . GLN D 1 57  ? 8.130   22.890  37.626 1.00 17.41  ? 259 GLN D CB  1 
ATOM   9736  C CG  . GLN D 1 57  ? 8.835   21.882  36.765 1.00 18.16  ? 259 GLN D CG  1 
ATOM   9737  C CD  . GLN D 1 57  ? 7.862   21.115  35.916 1.00 20.49  ? 259 GLN D CD  1 
ATOM   9738  O OE1 . GLN D 1 57  ? 6.656   21.173  36.136 1.00 24.11  ? 259 GLN D OE1 1 
ATOM   9739  N NE2 . GLN D 1 57  ? 8.367   20.437  34.901 1.00 18.86  ? 259 GLN D NE2 1 
ATOM   9740  N N   . ILE D 1 58  ? 11.371  23.829  37.981 1.00 18.82  ? 260 ILE D N   1 
ATOM   9741  C CA  . ILE D 1 58  ? 12.546  24.254  37.235 1.00 19.61  ? 260 ILE D CA  1 
ATOM   9742  C C   . ILE D 1 58  ? 13.111  22.996  36.595 1.00 22.53  ? 260 ILE D C   1 
ATOM   9743  O O   . ILE D 1 58  ? 13.007  21.904  37.163 1.00 23.30  ? 260 ILE D O   1 
ATOM   9744  C CB  . ILE D 1 58  ? 13.585  24.948  38.119 1.00 19.45  ? 260 ILE D CB  1 
ATOM   9745  C CG1 . ILE D 1 58  ? 14.038  24.013  39.233 1.00 18.41  ? 260 ILE D CG1 1 
ATOM   9746  C CG2 . ILE D 1 58  ? 13.011  26.216  38.711 1.00 16.26  ? 260 ILE D CG2 1 
ATOM   9747  C CD1 . ILE D 1 58  ? 15.179  24.549  40.022 1.00 17.82  ? 260 ILE D CD1 1 
ATOM   9748  N N   . SER D 1 59  ? 13.695  23.133  35.413 1.00 27.95  ? 261 SER D N   1 
ATOM   9749  C CA  . SER D 1 59  ? 14.207  21.974  34.709 1.00 30.34  ? 261 SER D CA  1 
ATOM   9750  C C   . SER D 1 59  ? 15.337  22.372  33.766 1.00 32.96  ? 261 SER D C   1 
ATOM   9751  O O   . SER D 1 59  ? 15.762  23.526  33.703 1.00 32.84  ? 261 SER D O   1 
ATOM   9752  C CB  . SER D 1 59  ? 13.083  21.272  33.949 1.00 30.28  ? 261 SER D CB  1 
ATOM   9753  O OG  . SER D 1 59  ? 12.549  22.109  32.942 1.00 29.39  ? 261 SER D OG  1 
ATOM   9754  N N   . ASN D 1 60  ? 15.831  21.382  33.025 1.00 35.61  ? 262 ASN D N   1 
ATOM   9755  C CA  . ASN D 1 60  ? 16.904  21.619  32.069 1.00 39.01  ? 262 ASN D CA  1 
ATOM   9756  C C   . ASN D 1 60  ? 16.476  22.611  30.996 1.00 41.89  ? 262 ASN D C   1 
ATOM   9757  O O   . ASN D 1 60  ? 17.269  23.456  30.567 1.00 42.22  ? 262 ASN D O   1 
ATOM   9758  C CB  . ASN D 1 60  ? 17.320  20.293  31.436 1.00 38.59  ? 262 ASN D CB  1 
ATOM   9759  C CG  . ASN D 1 60  ? 18.612  20.391  30.681 1.00 38.08  ? 262 ASN D CG  1 
ATOM   9760  O OD1 . ASN D 1 60  ? 19.515  21.128  31.072 1.00 37.62  ? 262 ASN D OD1 1 
ATOM   9761  N ND2 . ASN D 1 60  ? 18.710  19.658  29.580 1.00 38.13  ? 262 ASN D ND2 1 
ATOM   9762  N N   . SER D 1 61  ? 15.217  22.530  30.559 1.00 43.43  ? 263 SER D N   1 
ATOM   9763  C CA  . SER D 1 61  ? 14.766  23.350  29.440 1.00 47.06  ? 263 SER D CA  1 
ATOM   9764  C C   . SER D 1 61  ? 14.555  24.800  29.857 1.00 49.21  ? 263 SER D C   1 
ATOM   9765  O O   . SER D 1 61  ? 14.662  25.712  29.028 1.00 49.82  ? 263 SER D O   1 
ATOM   9766  C CB  . SER D 1 61  ? 13.483  22.765  28.848 1.00 49.29  ? 263 SER D CB  1 
ATOM   9767  O OG  . SER D 1 61  ? 12.425  22.790  29.788 1.00 50.67  ? 263 SER D OG  1 
ATOM   9768  N N   . THR D 1 62  ? 14.251  25.036  31.136 1.00 49.44  ? 264 THR D N   1 
ATOM   9769  C CA  . THR D 1 62  ? 14.058  26.404  31.610 1.00 51.06  ? 264 THR D CA  1 
ATOM   9770  C C   . THR D 1 62  ? 15.337  27.223  31.477 1.00 52.84  ? 264 THR D C   1 
ATOM   9771  O O   . THR D 1 62  ? 15.297  28.386  31.059 1.00 52.47  ? 264 THR D O   1 
ATOM   9772  C CB  . THR D 1 62  ? 13.574  26.397  33.061 1.00 45.99  ? 264 THR D CB  1 
ATOM   9773  O OG1 . THR D 1 62  ? 12.290  25.764  33.137 1.00 44.71  ? 264 THR D OG1 1 
ATOM   9774  C CG2 . THR D 1 62  ? 13.471  27.814  33.601 1.00 45.46  ? 264 THR D CG2 1 
ATOM   9775  N N   . SER D 1 63  ? 16.484  26.629  31.815 1.00 54.18  ? 265 SER D N   1 
ATOM   9776  C CA  . SER D 1 63  ? 17.749  27.347  31.691 1.00 55.97  ? 265 SER D CA  1 
ATOM   9777  C C   . SER D 1 63  ? 18.330  27.215  30.287 1.00 57.52  ? 265 SER D C   1 
ATOM   9778  O O   . SER D 1 63  ? 19.394  27.770  29.992 1.00 57.92  ? 265 SER D O   1 
ATOM   9779  C CB  . SER D 1 63  ? 18.742  26.838  32.734 1.00 52.41  ? 265 SER D CB  1 
ATOM   9780  O OG  . SER D 1 63  ? 18.291  27.122  34.045 1.00 54.03  ? 265 SER D OG  1 
ATOM   9781  N N   . GLY D 1 64  ? 17.643  26.489  29.408 1.00 56.73  ? 266 GLY D N   1 
ATOM   9782  C CA  . GLY D 1 64  ? 18.079  26.321  28.035 1.00 58.00  ? 266 GLY D CA  1 
ATOM   9783  C C   . GLY D 1 64  ? 18.716  24.978  27.738 1.00 58.87  ? 266 GLY D C   1 
ATOM   9784  O O   . GLY D 1 64  ? 18.710  24.529  26.588 1.00 59.53  ? 266 GLY D O   1 
ATOM   9785  N N   . GLY D 1 65  ? 19.257  24.324  28.764 1.00 56.00  ? 267 GLY D N   1 
ATOM   9786  C CA  . GLY D 1 65  ? 19.718  22.952  28.650 1.00 54.86  ? 267 GLY D CA  1 
ATOM   9787  C C   . GLY D 1 65  ? 20.723  22.646  27.559 1.00 53.84  ? 267 GLY D C   1 
ATOM   9788  O O   . GLY D 1 65  ? 21.806  23.238  27.509 1.00 53.33  ? 267 GLY D O   1 
ATOM   9789  N N   . SER D 1 66  ? 20.373  21.681  26.705 1.00 57.24  ? 268 SER D N   1 
ATOM   9790  C CA  . SER D 1 66  ? 21.114  21.229  25.523 1.00 55.50  ? 268 SER D CA  1 
ATOM   9791  C C   . SER D 1 66  ? 22.316  20.358  25.864 1.00 53.86  ? 268 SER D C   1 
ATOM   9792  O O   . SER D 1 66  ? 22.983  19.866  24.940 1.00 53.24  ? 268 SER D O   1 
ATOM   9793  C CB  . SER D 1 66  ? 21.576  22.391  24.636 1.00 61.74  ? 268 SER D CB  1 
ATOM   9794  O OG  . SER D 1 66  ? 20.468  23.073  24.074 1.00 61.33  ? 268 SER D OG  1 
ATOM   9795  N N   . SER D 1 67  ? 22.627  20.150  27.141 1.00 49.09  ? 269 SER D N   1 
ATOM   9796  C CA  . SER D 1 67  ? 23.726  19.280  27.540 1.00 46.28  ? 269 SER D CA  1 
ATOM   9797  C C   . SER D 1 67  ? 23.166  18.065  28.262 1.00 44.58  ? 269 SER D C   1 
ATOM   9798  O O   . SER D 1 67  ? 22.301  18.201  29.133 1.00 43.62  ? 269 SER D O   1 
ATOM   9799  C CB  . SER D 1 67  ? 24.727  20.012  28.437 1.00 46.48  ? 269 SER D CB  1 
ATOM   9800  O OG  . SER D 1 67  ? 25.775  19.145  28.831 1.00 45.08  ? 269 SER D OG  1 
ATOM   9801  N N   . ASN D 1 68  ? 23.661  16.881  27.896 1.00 41.53  ? 270 ASN D N   1 
ATOM   9802  C CA  . ASN D 1 68  ? 23.185  15.649  28.518 1.00 39.79  ? 270 ASN D CA  1 
ATOM   9803  C C   . ASN D 1 68  ? 23.588  15.583  29.985 1.00 37.65  ? 270 ASN D C   1 
ATOM   9804  O O   . ASN D 1 68  ? 22.747  15.333  30.854 1.00 36.67  ? 270 ASN D O   1 
ATOM   9805  C CB  . ASN D 1 68  ? 23.730  14.443  27.751 1.00 44.05  ? 270 ASN D CB  1 
ATOM   9806  C CG  . ASN D 1 68  ? 23.139  13.115  28.220 1.00 45.74  ? 270 ASN D CG  1 
ATOM   9807  O OD1 . ASN D 1 68  ? 22.625  12.994  29.331 1.00 45.24  ? 270 ASN D OD1 1 
ATOM   9808  N ND2 . ASN D 1 68  ? 23.217  12.108  27.358 1.00 46.01  ? 270 ASN D ND2 1 
ATOM   9809  N N   . ASP D 1 69  ? 24.869  15.804  30.278 1.00 36.07  ? 271 ASP D N   1 
ATOM   9810  C CA  . ASP D 1 69  ? 25.352  15.691  31.647 1.00 33.70  ? 271 ASP D CA  1 
ATOM   9811  C C   . ASP D 1 69  ? 24.760  16.749  32.565 1.00 31.32  ? 271 ASP D C   1 
ATOM   9812  O O   . ASP D 1 69  ? 24.804  16.584  33.787 1.00 31.16  ? 271 ASP D O   1 
ATOM   9813  C CB  . ASP D 1 69  ? 26.876  15.781  31.665 1.00 30.94  ? 271 ASP D CB  1 
ATOM   9814  C CG  . ASP D 1 69  ? 27.537  14.579  31.021 1.00 33.45  ? 271 ASP D CG  1 
ATOM   9815  O OD1 . ASP D 1 69  ? 26.865  13.537  30.875 1.00 34.19  ? 271 ASP D OD1 1 
ATOM   9816  O OD2 . ASP D 1 69  ? 28.722  14.681  30.646 1.00 34.31  ? 271 ASP D OD2 1 
ATOM   9817  N N   . ASN D 1 70  ? 24.225  17.834  32.009 1.00 34.07  ? 272 ASN D N   1 
ATOM   9818  C CA  . ASN D 1 70  ? 23.685  18.938  32.788 1.00 31.61  ? 272 ASN D CA  1 
ATOM   9819  C C   . ASN D 1 70  ? 22.169  18.911  32.938 1.00 29.59  ? 272 ASN D C   1 
ATOM   9820  O O   . ASN D 1 70  ? 21.609  19.840  33.525 1.00 29.57  ? 272 ASN D O   1 
ATOM   9821  C CB  . ASN D 1 70  ? 24.124  20.267  32.169 1.00 31.79  ? 272 ASN D CB  1 
ATOM   9822  C CG  . ASN D 1 70  ? 25.609  20.507  32.321 1.00 32.11  ? 272 ASN D CG  1 
ATOM   9823  O OD1 . ASN D 1 70  ? 26.239  19.985  33.236 1.00 33.44  ? 272 ASN D OD1 1 
ATOM   9824  N ND2 . ASN D 1 70  ? 26.178  21.286  31.415 1.00 33.06  ? 272 ASN D ND2 1 
ATOM   9825  N N   . ALA D 1 71  ? 21.487  17.894  32.415 1.00 30.64  ? 273 ALA D N   1 
ATOM   9826  C CA  . ALA D 1 71  ? 20.035  17.836  32.518 1.00 27.86  ? 273 ALA D CA  1 
ATOM   9827  C C   . ALA D 1 71  ? 19.596  17.626  33.963 1.00 26.43  ? 273 ALA D C   1 
ATOM   9828  O O   . ALA D 1 71  ? 20.155  16.804  34.693 1.00 26.79  ? 273 ALA D O   1 
ATOM   9829  C CB  . ALA D 1 71  ? 19.485  16.716  31.638 1.00 26.23  ? 273 ALA D CB  1 
ATOM   9830  N N   . TYR D 1 72  ? 18.582  18.386  34.379 1.00 24.89  ? 274 TYR D N   1 
ATOM   9831  C CA  . TYR D 1 72  ? 18.089  18.286  35.747 1.00 22.79  ? 274 TYR D CA  1 
ATOM   9832  C C   . TYR D 1 72  ? 16.610  18.641  35.789 1.00 21.25  ? 274 TYR D C   1 
ATOM   9833  O O   . TYR D 1 72  ? 16.072  19.264  34.873 1.00 20.72  ? 274 TYR D O   1 
ATOM   9834  C CB  . TYR D 1 72  ? 18.890  19.180  36.701 1.00 23.42  ? 274 TYR D CB  1 
ATOM   9835  C CG  . TYR D 1 72  ? 18.784  20.656  36.415 1.00 23.91  ? 274 TYR D CG  1 
ATOM   9836  C CD1 . TYR D 1 72  ? 17.820  21.435  37.037 1.00 24.84  ? 274 TYR D CD1 1 
ATOM   9837  C CD2 . TYR D 1 72  ? 19.640  21.270  35.519 1.00 24.24  ? 274 TYR D CD2 1 
ATOM   9838  C CE1 . TYR D 1 72  ? 17.717  22.782  36.781 1.00 25.40  ? 274 TYR D CE1 1 
ATOM   9839  C CE2 . TYR D 1 72  ? 19.546  22.616  35.255 1.00 24.85  ? 274 TYR D CE2 1 
ATOM   9840  C CZ  . TYR D 1 72  ? 18.583  23.367  35.889 1.00 25.47  ? 274 TYR D CZ  1 
ATOM   9841  O OH  . TYR D 1 72  ? 18.487  24.711  35.627 1.00 25.73  ? 274 TYR D OH  1 
ATOM   9842  N N   . PHE D 1 73  ? 15.965  18.226  36.876 1.00 17.23  ? 275 PHE D N   1 
ATOM   9843  C CA  . PHE D 1 73  ? 14.562  18.488  37.146 1.00 16.54  ? 275 PHE D CA  1 
ATOM   9844  C C   . PHE D 1 73  ? 14.404  18.687  38.644 1.00 16.85  ? 275 PHE D C   1 
ATOM   9845  O O   . PHE D 1 73  ? 14.999  17.954  39.436 1.00 17.36  ? 275 PHE D O   1 
ATOM   9846  C CB  . PHE D 1 73  ? 13.680  17.328  36.664 1.00 14.98  ? 275 PHE D CB  1 
ATOM   9847  C CG  . PHE D 1 73  ? 12.218  17.497  36.960 1.00 14.78  ? 275 PHE D CG  1 
ATOM   9848  C CD1 . PHE D 1 73  ? 11.399  18.191  36.093 1.00 15.06  ? 275 PHE D CD1 1 
ATOM   9849  C CD2 . PHE D 1 73  ? 11.663  16.960  38.105 1.00 15.05  ? 275 PHE D CD2 1 
ATOM   9850  C CE1 . PHE D 1 73  ? 10.061  18.337  36.362 1.00 14.80  ? 275 PHE D CE1 1 
ATOM   9851  C CE2 . PHE D 1 73  ? 10.328  17.118  38.381 1.00 15.39  ? 275 PHE D CE2 1 
ATOM   9852  C CZ  . PHE D 1 73  ? 9.526   17.803  37.508 1.00 15.65  ? 275 PHE D CZ  1 
ATOM   9853  N N   . GLY D 1 74  ? 13.594  19.663  39.029 1.00 16.05  ? 276 GLY D N   1 
ATOM   9854  C CA  . GLY D 1 74  ? 13.459  19.984  40.435 1.00 15.35  ? 276 GLY D CA  1 
ATOM   9855  C C   . GLY D 1 74  ? 12.435  21.070  40.653 1.00 15.85  ? 276 GLY D C   1 
ATOM   9856  O O   . GLY D 1 74  ? 11.576  21.310  39.805 1.00 16.84  ? 276 GLY D O   1 
ATOM   9857  N N   . TYR D 1 75  ? 12.527  21.718  41.812 1.00 15.62  ? 277 TYR D N   1 
ATOM   9858  C CA  . TYR D 1 75  ? 11.576  22.749  42.200 1.00 15.19  ? 277 TYR D CA  1 
ATOM   9859  C C   . TYR D 1 75  ? 12.281  23.844  42.983 1.00 15.50  ? 277 TYR D C   1 
ATOM   9860  O O   . TYR D 1 75  ? 13.147  23.565  43.814 1.00 15.90  ? 277 TYR D O   1 
ATOM   9861  C CB  . TYR D 1 75  ? 10.445  22.161  43.047 1.00 13.54  ? 277 TYR D CB  1 
ATOM   9862  C CG  . TYR D 1 75  ? 9.624   21.130  42.321 1.00 13.96  ? 277 TYR D CG  1 
ATOM   9863  C CD1 . TYR D 1 75  ? 8.543   21.502  41.544 1.00 15.18  ? 277 TYR D CD1 1 
ATOM   9864  C CD2 . TYR D 1 75  ? 9.935   19.783  42.407 1.00 13.14  ? 277 TYR D CD2 1 
ATOM   9865  C CE1 . TYR D 1 75  ? 7.797   20.570  40.877 1.00 17.16  ? 277 TYR D CE1 1 
ATOM   9866  C CE2 . TYR D 1 75  ? 9.193   18.843  41.739 1.00 14.70  ? 277 TYR D CE2 1 
ATOM   9867  C CZ  . TYR D 1 75  ? 8.125   19.245  40.976 1.00 16.74  ? 277 TYR D CZ  1 
ATOM   9868  O OH  . TYR D 1 75  ? 7.373   18.319  40.305 1.00 18.80  ? 277 TYR D OH  1 
ATOM   9869  N N   . SER D 1 76  ? 11.903  25.089  42.714 1.00 17.52  ? 278 SER D N   1 
ATOM   9870  C CA  . SER D 1 76  ? 12.342  26.234  43.495 1.00 18.35  ? 278 SER D CA  1 
ATOM   9871  C C   . SER D 1 76  ? 11.214  26.670  44.419 1.00 18.77  ? 278 SER D C   1 
ATOM   9872  O O   . SER D 1 76  ? 10.047  26.690  44.023 1.00 19.09  ? 278 SER D O   1 
ATOM   9873  C CB  . SER D 1 76  ? 12.771  27.393  42.594 1.00 19.99  ? 278 SER D CB  1 
ATOM   9874  O OG  . SER D 1 76  ? 11.689  27.866  41.821 1.00 21.68  ? 278 SER D OG  1 
ATOM   9875  N N   . THR D 1 77  ? 11.564  27.024  45.645 1.00 21.14  ? 279 THR D N   1 
ATOM   9876  C CA  . THR D 1 77  ? 10.590  27.236  46.699 1.00 20.83  ? 279 THR D CA  1 
ATOM   9877  C C   . THR D 1 77  ? 10.539  28.704  47.097 1.00 20.94  ? 279 THR D C   1 
ATOM   9878  O O   . THR D 1 77  ? 11.536  29.425  46.978 1.00 22.29  ? 279 THR D O   1 
ATOM   9879  C CB  . THR D 1 77  ? 10.935  26.392  47.933 1.00 20.96  ? 279 THR D CB  1 
ATOM   9880  O OG1 . THR D 1 77  ? 12.208  26.800  48.441 1.00 20.92  ? 279 THR D OG1 1 
ATOM   9881  C CG2 . THR D 1 77  ? 11.008  24.928  47.564 1.00 18.44  ? 279 THR D CG2 1 
ATOM   9882  N N   . PRO D 1 78  ? 9.383   29.183  47.567 1.00 24.90  ? 280 PRO D N   1 
ATOM   9883  C CA  . PRO D 1 78  ? 9.326   30.529  48.150 1.00 24.74  ? 280 PRO D CA  1 
ATOM   9884  C C   . PRO D 1 78  ? 10.086  30.654  49.457 1.00 24.92  ? 280 PRO D C   1 
ATOM   9885  O O   . PRO D 1 78  ? 10.327  31.780  49.910 1.00 26.72  ? 280 PRO D O   1 
ATOM   9886  C CB  . PRO D 1 78  ? 7.824   30.756  48.350 1.00 22.95  ? 280 PRO D CB  1 
ATOM   9887  C CG  . PRO D 1 78  ? 7.255   29.398  48.472 1.00 22.67  ? 280 PRO D CG  1 
ATOM   9888  C CD  . PRO D 1 78  ? 8.065   28.530  47.562 1.00 23.04  ? 280 PRO D CD  1 
ATOM   9889  N N   . TRP D 1 79  ? 10.456  29.540  50.074 1.00 23.88  ? 281 TRP D N   1 
ATOM   9890  C CA  . TRP D 1 79  ? 11.149  29.537  51.350 1.00 23.34  ? 281 TRP D CA  1 
ATOM   9891  C C   . TRP D 1 79  ? 12.633  29.831  51.182 1.00 23.72  ? 281 TRP D C   1 
ATOM   9892  O O   . TRP D 1 79  ? 13.243  29.501  50.163 1.00 24.48  ? 281 TRP D O   1 
ATOM   9893  C CB  . TRP D 1 79  ? 10.973  28.179  52.020 1.00 25.20  ? 281 TRP D CB  1 
ATOM   9894  C CG  . TRP D 1 79  ? 9.597   27.924  52.532 1.00 26.14  ? 281 TRP D CG  1 
ATOM   9895  C CD1 . TRP D 1 79  ? 8.527   27.484  51.816 1.00 26.87  ? 281 TRP D CD1 1 
ATOM   9896  C CD2 . TRP D 1 79  ? 9.162   28.011  53.890 1.00 26.88  ? 281 TRP D CD2 1 
ATOM   9897  N NE1 . TRP D 1 79  ? 7.440   27.336  52.634 1.00 27.42  ? 281 TRP D NE1 1 
ATOM   9898  C CE2 . TRP D 1 79  ? 7.806   27.644  53.917 1.00 26.55  ? 281 TRP D CE2 1 
ATOM   9899  C CE3 . TRP D 1 79  ? 9.784   28.379  55.083 1.00 27.56  ? 281 TRP D CE3 1 
ATOM   9900  C CZ2 . TRP D 1 79  ? 7.057   27.640  55.089 1.00 26.51  ? 281 TRP D CZ2 1 
ATOM   9901  C CZ3 . TRP D 1 79  ? 9.041   28.372  56.247 1.00 28.16  ? 281 TRP D CZ3 1 
ATOM   9902  C CH2 . TRP D 1 79  ? 7.691   28.005  56.241 1.00 28.32  ? 281 TRP D CH2 1 
ATOM   9903  N N   . GLY D 1 80  ? 13.209  30.473  52.198 1.00 26.57  ? 282 GLY D N   1 
ATOM   9904  C CA  . GLY D 1 80  ? 14.641  30.613  52.329 1.00 26.76  ? 282 GLY D CA  1 
ATOM   9905  C C   . GLY D 1 80  ? 15.176  29.713  53.435 1.00 27.43  ? 282 GLY D C   1 
ATOM   9906  O O   . GLY D 1 80  ? 14.428  29.056  54.153 1.00 26.93  ? 282 GLY D O   1 
ATOM   9907  N N   . TYR D 1 81  ? 16.500  29.709  53.577 1.00 29.56  ? 283 TYR D N   1 
ATOM   9908  C CA  . TYR D 1 81  ? 17.129  28.842  54.563 1.00 29.90  ? 283 TYR D CA  1 
ATOM   9909  C C   . TYR D 1 81  ? 18.401  29.484  55.100 1.00 31.16  ? 283 TYR D C   1 
ATOM   9910  O O   . TYR D 1 81  ? 19.059  30.269  54.413 1.00 31.31  ? 283 TYR D O   1 
ATOM   9911  C CB  . TYR D 1 81  ? 17.443  27.464  53.971 1.00 27.68  ? 283 TYR D CB  1 
ATOM   9912  C CG  . TYR D 1 81  ? 18.502  27.464  52.896 1.00 28.67  ? 283 TYR D CG  1 
ATOM   9913  C CD1 . TYR D 1 81  ? 19.833  27.238  53.208 1.00 29.34  ? 283 TYR D CD1 1 
ATOM   9914  C CD2 . TYR D 1 81  ? 18.173  27.688  51.570 1.00 29.21  ? 283 TYR D CD2 1 
ATOM   9915  C CE1 . TYR D 1 81  ? 20.803  27.233  52.230 1.00 30.67  ? 283 TYR D CE1 1 
ATOM   9916  C CE2 . TYR D 1 81  ? 19.134  27.684  50.587 1.00 30.39  ? 283 TYR D CE2 1 
ATOM   9917  C CZ  . TYR D 1 81  ? 20.448  27.456  50.921 1.00 30.81  ? 283 TYR D CZ  1 
ATOM   9918  O OH  . TYR D 1 81  ? 21.412  27.454  49.942 1.00 30.30  ? 283 TYR D OH  1 
ATOM   9919  N N   . PHE D 1 82  ? 18.761  29.107  56.325 1.00 32.12  ? 284 PHE D N   1 
ATOM   9920  C CA  . PHE D 1 82  ? 19.954  29.601  57.011 1.00 33.57  ? 284 PHE D CA  1 
ATOM   9921  C C   . PHE D 1 82  ? 21.114  28.618  56.966 1.00 36.58  ? 284 PHE D C   1 
ATOM   9922  O O   . PHE D 1 82  ? 20.972  27.468  57.365 1.00 37.73  ? 284 PHE D O   1 
ATOM   9923  C CB  . PHE D 1 82  ? 19.649  29.860  58.482 1.00 35.76  ? 284 PHE D CB  1 
ATOM   9924  C CG  . PHE D 1 82  ? 19.011  31.181  58.743 1.00 36.32  ? 284 PHE D CG  1 
ATOM   9925  C CD1 . PHE D 1 82  ? 19.752  32.341  58.672 1.00 35.65  ? 284 PHE D CD1 1 
ATOM   9926  C CD2 . PHE D 1 82  ? 17.675  31.262  59.070 1.00 36.89  ? 284 PHE D CD2 1 
ATOM   9927  C CE1 . PHE D 1 82  ? 19.166  33.562  58.913 1.00 36.39  ? 284 PHE D CE1 1 
ATOM   9928  C CE2 . PHE D 1 82  ? 17.083  32.481  59.314 1.00 37.17  ? 284 PHE D CE2 1 
ATOM   9929  C CZ  . PHE D 1 82  ? 17.829  33.632  59.235 1.00 37.17  ? 284 PHE D CZ  1 
ATOM   9930  N N   . ASP D 1 83  ? 22.269  29.067  56.492 1.00 40.42  ? 285 ASP D N   1 
ATOM   9931  C CA  . ASP D 1 83  ? 23.432  28.194  56.438 1.00 42.09  ? 285 ASP D CA  1 
ATOM   9932  C C   . ASP D 1 83  ? 24.703  28.759  57.070 1.00 39.61  ? 285 ASP D C   1 
ATOM   9933  O O   . ASP D 1 83  ? 25.086  29.892  56.799 1.00 40.16  ? 285 ASP D O   1 
ATOM   9934  C CB  . ASP D 1 83  ? 23.729  27.799  54.997 1.00 34.97  ? 285 ASP D CB  1 
ATOM   9935  C CG  . ASP D 1 83  ? 24.781  26.725  54.905 1.00 41.33  ? 285 ASP D CG  1 
ATOM   9936  O OD1 . ASP D 1 83  ? 25.134  26.162  55.962 1.00 45.79  ? 285 ASP D OD1 1 
ATOM   9937  O OD2 . ASP D 1 83  ? 25.248  26.441  53.785 1.00 44.72  ? 285 ASP D OD2 1 
ATOM   9938  N N   . PHE D 1 84  ? 25.350  27.965  57.915 1.00 40.17  ? 286 PHE D N   1 
ATOM   9939  C CA  . PHE D 1 84  ? 26.617  28.359  58.513 1.00 37.56  ? 286 PHE D CA  1 
ATOM   9940  C C   . PHE D 1 84  ? 27.549  27.171  58.342 1.00 35.62  ? 286 PHE D C   1 
ATOM   9941  O O   . PHE D 1 84  ? 27.916  26.505  59.302 1.00 35.15  ? 286 PHE D O   1 
ATOM   9942  C CB  . PHE D 1 84  ? 26.466  28.767  59.980 1.00 36.38  ? 286 PHE D CB  1 
ATOM   9943  C CG  . PHE D 1 84  ? 25.594  27.854  60.783 1.00 36.88  ? 286 PHE D CG  1 
ATOM   9944  C CD1 . PHE D 1 84  ? 26.130  26.757  61.429 1.00 37.41  ? 286 PHE D CD1 1 
ATOM   9945  C CD2 . PHE D 1 84  ? 24.242  28.103  60.906 1.00 37.13  ? 286 PHE D CD2 1 
ATOM   9946  C CE1 . PHE D 1 84  ? 25.331  25.915  62.174 1.00 37.20  ? 286 PHE D CE1 1 
ATOM   9947  C CE2 . PHE D 1 84  ? 23.438  27.267  61.649 1.00 37.91  ? 286 PHE D CE2 1 
ATOM   9948  C CZ  . PHE D 1 84  ? 23.981  26.171  62.284 1.00 37.28  ? 286 PHE D CZ  1 
ATOM   9949  N N   . ASN D 1 85  ? 27.940  26.931  57.097 1.00 37.91  ? 287 ASN D N   1 
ATOM   9950  C CA  . ASN D 1 85  ? 28.776  25.793  56.741 1.00 36.76  ? 287 ASN D CA  1 
ATOM   9951  C C   . ASN D 1 85  ? 30.257  26.059  56.512 1.00 36.48  ? 287 ASN D C   1 
ATOM   9952  O O   . ASN D 1 85  ? 30.942  25.213  55.954 1.00 37.28  ? 287 ASN D O   1 
ATOM   9953  C CB  . ASN D 1 85  ? 28.205  25.080  55.521 1.00 37.50  ? 287 ASN D CB  1 
ATOM   9954  C CG  . ASN D 1 85  ? 28.502  23.601  55.527 1.00 38.29  ? 287 ASN D CG  1 
ATOM   9955  O OD1 . ASN D 1 85  ? 28.581  22.981  56.582 1.00 36.87  ? 287 ASN D OD1 1 
ATOM   9956  N ND2 . ASN D 1 85  ? 28.661  23.027  54.347 1.00 40.74  ? 287 ASN D ND2 1 
ATOM   9957  N N   . ARG D 1 86  ? 30.745  27.235  56.880 1.00 35.93  ? 288 ARG D N   1 
ATOM   9958  C CA  . ARG D 1 86  ? 32.158  27.537  56.708 1.00 36.00  ? 288 ARG D CA  1 
ATOM   9959  C C   . ARG D 1 86  ? 32.760  27.933  58.045 1.00 36.25  ? 288 ARG D C   1 
ATOM   9960  O O   . ARG D 1 86  ? 32.060  28.463  58.898 1.00 36.35  ? 288 ARG D O   1 
ATOM   9961  C CB  . ARG D 1 86  ? 32.338  28.629  55.665 1.00 33.62  ? 288 ARG D CB  1 
ATOM   9962  C CG  . ARG D 1 86  ? 31.642  28.296  54.362 1.00 34.13  ? 288 ARG D CG  1 
ATOM   9963  C CD  . ARG D 1 86  ? 31.700  29.445  53.385 1.00 35.01  ? 288 ARG D CD  1 
ATOM   9964  N NE  . ARG D 1 86  ? 33.002  29.556  52.752 1.00 36.33  ? 288 ARG D NE  1 
ATOM   9965  C CZ  . ARG D 1 86  ? 33.231  30.295  51.679 1.00 37.20  ? 288 ARG D CZ  1 
ATOM   9966  N NH1 . ARG D 1 86  ? 32.243  30.976  51.132 1.00 36.78  ? 288 ARG D NH1 1 
ATOM   9967  N NH2 . ARG D 1 86  ? 34.439  30.349  51.150 1.00 35.28  ? 288 ARG D NH2 1 
ATOM   9968  N N   . PHE D 1 87  ? 34.051  27.670  58.235 1.00 37.54  ? 289 PHE D N   1 
ATOM   9969  C CA  . PHE D 1 87  ? 34.708  27.991  59.498 1.00 38.26  ? 289 PHE D CA  1 
ATOM   9970  C C   . PHE D 1 87  ? 34.775  29.493  59.742 1.00 39.57  ? 289 PHE D C   1 
ATOM   9971  O O   . PHE D 1 87  ? 34.570  29.952  60.871 1.00 39.16  ? 289 PHE D O   1 
ATOM   9972  C CB  . PHE D 1 87  ? 36.112  27.387  59.529 1.00 38.17  ? 289 PHE D CB  1 
ATOM   9973  C CG  . PHE D 1 87  ? 36.131  25.889  59.601 1.00 38.48  ? 289 PHE D CG  1 
ATOM   9974  C CD1 . PHE D 1 87  ? 36.053  25.244  60.820 1.00 37.54  ? 289 PHE D CD1 1 
ATOM   9975  C CD2 . PHE D 1 87  ? 36.228  25.126  58.455 1.00 38.08  ? 289 PHE D CD2 1 
ATOM   9976  C CE1 . PHE D 1 87  ? 36.073  23.868  60.892 1.00 37.95  ? 289 PHE D CE1 1 
ATOM   9977  C CE2 . PHE D 1 87  ? 36.247  23.752  58.523 1.00 37.57  ? 289 PHE D CE2 1 
ATOM   9978  C CZ  . PHE D 1 87  ? 36.170  23.122  59.743 1.00 37.27  ? 289 PHE D CZ  1 
ATOM   9979  N N   . HIS D 1 88  ? 35.064  30.278  58.698 1.00 37.62  ? 290 HIS D N   1 
ATOM   9980  C CA  . HIS D 1 88  ? 35.231  31.716  58.886 1.00 39.35  ? 290 HIS D CA  1 
ATOM   9981  C C   . HIS D 1 88  ? 33.959  32.392  59.379 1.00 40.44  ? 290 HIS D C   1 
ATOM   9982  O O   . HIS D 1 88  ? 34.025  33.525  59.868 1.00 41.91  ? 290 HIS D O   1 
ATOM   9983  C CB  . HIS D 1 88  ? 35.709  32.380  57.594 1.00 35.24  ? 290 HIS D CB  1 
ATOM   9984  C CG  . HIS D 1 88  ? 34.788  32.189  56.433 1.00 36.45  ? 290 HIS D CG  1 
ATOM   9985  N ND1 . HIS D 1 88  ? 33.595  32.865  56.308 1.00 38.40  ? 290 HIS D ND1 1 
ATOM   9986  C CD2 . HIS D 1 88  ? 34.898  31.414  55.329 1.00 36.11  ? 290 HIS D CD2 1 
ATOM   9987  C CE1 . HIS D 1 88  ? 33.003  32.506  55.184 1.00 37.66  ? 290 HIS D CE1 1 
ATOM   9988  N NE2 . HIS D 1 88  ? 33.775  31.629  54.570 1.00 36.89  ? 290 HIS D NE2 1 
ATOM   9989  N N   . CYS D 1 89  ? 32.807  31.732  59.253 1.00 38.79  ? 291 CYS D N   1 
ATOM   9990  C CA  . CYS D 1 89  ? 31.618  32.198  59.955 1.00 40.68  ? 291 CYS D CA  1 
ATOM   9991  C C   . CYS D 1 89  ? 31.855  32.212  61.457 1.00 39.63  ? 291 CYS D C   1 
ATOM   9992  O O   . CYS D 1 89  ? 31.530  33.189  62.140 1.00 39.00  ? 291 CYS D O   1 
ATOM   9993  C CB  . CYS D 1 89  ? 30.425  31.300  59.627 1.00 36.14  ? 291 CYS D CB  1 
ATOM   9994  S SG  . CYS D 1 89  ? 29.938  31.244  57.895 1.00 44.97  ? 291 CYS D SG  1 
ATOM   9995  N N   . HIS D 1 90  ? 32.405  31.122  61.989 1.00 40.56  ? 292 HIS D N   1 
ATOM   9996  C CA  . HIS D 1 90  ? 32.597  30.944  63.419 1.00 39.49  ? 292 HIS D CA  1 
ATOM   9997  C C   . HIS D 1 90  ? 33.987  31.336  63.909 1.00 39.22  ? 292 HIS D C   1 
ATOM   9998  O O   . HIS D 1 90  ? 34.191  31.422  65.124 1.00 40.58  ? 292 HIS D O   1 
ATOM   9999  C CB  . HIS D 1 90  ? 32.331  29.482  63.777 1.00 38.48  ? 292 HIS D CB  1 
ATOM   10000 C CG  . HIS D 1 90  ? 31.037  28.960  63.234 1.00 39.53  ? 292 HIS D CG  1 
ATOM   10001 N ND1 . HIS D 1 90  ? 29.810  29.365  63.711 1.00 41.00  ? 292 HIS D ND1 1 
ATOM   10002 C CD2 . HIS D 1 90  ? 30.782  28.081  62.238 1.00 39.83  ? 292 HIS D CD2 1 
ATOM   10003 C CE1 . HIS D 1 90  ? 28.854  28.751  63.038 1.00 41.55  ? 292 HIS D CE1 1 
ATOM   10004 N NE2 . HIS D 1 90  ? 29.418  27.966  62.138 1.00 40.71  ? 292 HIS D NE2 1 
ATOM   10005 N N   . PHE D 1 91  ? 34.941  31.580  63.012 1.00 41.40  ? 293 PHE D N   1 
ATOM   10006 C CA  . PHE D 1 91  ? 36.338  31.785  63.384 1.00 40.43  ? 293 PHE D CA  1 
ATOM   10007 C C   . PHE D 1 91  ? 36.859  33.075  62.772 1.00 40.87  ? 293 PHE D C   1 
ATOM   10008 O O   . PHE D 1 91  ? 36.821  33.247  61.549 1.00 42.48  ? 293 PHE D O   1 
ATOM   10009 C CB  . PHE D 1 91  ? 37.213  30.609  62.937 1.00 39.55  ? 293 PHE D CB  1 
ATOM   10010 C CG  . PHE D 1 91  ? 36.978  29.340  63.703 1.00 39.28  ? 293 PHE D CG  1 
ATOM   10011 C CD1 . PHE D 1 91  ? 37.672  29.083  64.873 1.00 39.38  ? 293 PHE D CD1 1 
ATOM   10012 C CD2 . PHE D 1 91  ? 36.061  28.403  63.257 1.00 39.76  ? 293 PHE D CD2 1 
ATOM   10013 C CE1 . PHE D 1 91  ? 37.458  27.915  65.580 1.00 39.62  ? 293 PHE D CE1 1 
ATOM   10014 C CE2 . PHE D 1 91  ? 35.841  27.236  63.960 1.00 40.31  ? 293 PHE D CE2 1 
ATOM   10015 C CZ  . PHE D 1 91  ? 36.541  26.991  65.123 1.00 40.02  ? 293 PHE D CZ  1 
ATOM   10016 N N   . SER D 1 92  ? 37.355  33.969  63.617 1.00 44.46  ? 294 SER D N   1 
ATOM   10017 C CA  . SER D 1 92  ? 38.160  35.077  63.148 1.00 43.83  ? 294 SER D CA  1 
ATOM   10018 C C   . SER D 1 92  ? 39.540  34.564  62.755 1.00 43.09  ? 294 SER D C   1 
ATOM   10019 O O   . SER D 1 92  ? 39.946  33.479  63.174 1.00 41.91  ? 294 SER D O   1 
ATOM   10020 C CB  . SER D 1 92  ? 38.276  36.141  64.232 1.00 41.79  ? 294 SER D CB  1 
ATOM   10021 O OG  . SER D 1 92  ? 38.956  35.637  65.366 1.00 43.01  ? 294 SER D OG  1 
ATOM   10022 N N   . PRO D 1 93  ? 40.272  35.312  61.926 1.00 40.68  ? 295 PRO D N   1 
ATOM   10023 C CA  . PRO D 1 93  ? 41.624  34.862  61.552 1.00 40.76  ? 295 PRO D CA  1 
ATOM   10024 C C   . PRO D 1 93  ? 42.520  34.575  62.744 1.00 41.54  ? 295 PRO D C   1 
ATOM   10025 O O   . PRO D 1 93  ? 43.282  33.601  62.720 1.00 40.85  ? 295 PRO D O   1 
ATOM   10026 C CB  . PRO D 1 93  ? 42.149  36.028  60.709 1.00 38.70  ? 295 PRO D CB  1 
ATOM   10027 C CG  . PRO D 1 93  ? 40.930  36.628  60.123 1.00 39.93  ? 295 PRO D CG  1 
ATOM   10028 C CD  . PRO D 1 93  ? 39.862  36.503  61.168 1.00 39.47  ? 295 PRO D CD  1 
ATOM   10029 N N   . ARG D 1 94  ? 42.449  35.396  63.793 1.00 42.37  ? 296 ARG D N   1 
ATOM   10030 C CA  . ARG D 1 94  ? 43.245  35.133  64.986 1.00 44.28  ? 296 ARG D CA  1 
ATOM   10031 C C   . ARG D 1 94  ? 42.772  33.871  65.693 1.00 43.95  ? 296 ARG D C   1 
ATOM   10032 O O   . ARG D 1 94  ? 43.584  33.005  66.038 1.00 43.34  ? 296 ARG D O   1 
ATOM   10033 C CB  . ARG D 1 94  ? 43.185  36.326  65.938 1.00 43.79  ? 296 ARG D CB  1 
ATOM   10034 C CG  . ARG D 1 94  ? 43.969  36.115  67.221 1.00 47.19  ? 296 ARG D CG  1 
ATOM   10035 C CD  . ARG D 1 94  ? 45.454  36.014  66.929 1.00 51.36  ? 296 ARG D CD  1 
ATOM   10036 N NE  . ARG D 1 94  ? 46.236  35.748  68.131 1.00 57.35  ? 296 ARG D NE  1 
ATOM   10037 C CZ  . ARG D 1 94  ? 46.524  34.530  68.575 1.00 59.46  ? 296 ARG D CZ  1 
ATOM   10038 N NH1 . ARG D 1 94  ? 46.107  33.468  67.905 1.00 59.03  ? 296 ARG D NH1 1 
ATOM   10039 N NH2 . ARG D 1 94  ? 47.241  34.373  69.678 1.00 59.25  ? 296 ARG D NH2 1 
ATOM   10040 N N   . ASP D 1 95  ? 41.461  33.748  65.920 1.00 47.50  ? 297 ASP D N   1 
ATOM   10041 C CA  . ASP D 1 95  ? 40.931  32.555  66.574 1.00 48.31  ? 297 ASP D CA  1 
ATOM   10042 C C   . ASP D 1 95  ? 41.239  31.303  65.765 1.00 46.49  ? 297 ASP D C   1 
ATOM   10043 O O   . ASP D 1 95  ? 41.531  30.244  66.331 1.00 46.10  ? 297 ASP D O   1 
ATOM   10044 C CB  . ASP D 1 95  ? 39.424  32.697  66.791 1.00 48.60  ? 297 ASP D CB  1 
ATOM   10045 C CG  . ASP D 1 95  ? 39.084  33.714  67.860 1.00 54.20  ? 297 ASP D CG  1 
ATOM   10046 O OD1 . ASP D 1 95  ? 39.990  34.091  68.631 1.00 55.84  ? 297 ASP D OD1 1 
ATOM   10047 O OD2 . ASP D 1 95  ? 37.910  34.133  67.936 1.00 57.33  ? 297 ASP D OD2 1 
ATOM   10048 N N   . TRP D 1 96  ? 41.182  31.408  64.438 1.00 43.74  ? 298 TRP D N   1 
ATOM   10049 C CA  . TRP D 1 96  ? 41.602  30.301  63.588 1.00 42.86  ? 298 TRP D CA  1 
ATOM   10050 C C   . TRP D 1 96  ? 43.096  30.046  63.720 1.00 42.98  ? 298 TRP D C   1 
ATOM   10051 O O   . TRP D 1 96  ? 43.546  28.897  63.663 1.00 42.67  ? 298 TRP D O   1 
ATOM   10052 C CB  . TRP D 1 96  ? 41.236  30.601  62.138 1.00 41.15  ? 298 TRP D CB  1 
ATOM   10053 C CG  . TRP D 1 96  ? 41.643  29.552  61.161 1.00 40.22  ? 298 TRP D CG  1 
ATOM   10054 C CD1 . TRP D 1 96  ? 42.708  29.592  60.316 1.00 39.81  ? 298 TRP D CD1 1 
ATOM   10055 C CD2 . TRP D 1 96  ? 40.971  28.317  60.900 1.00 41.01  ? 298 TRP D CD2 1 
ATOM   10056 N NE1 . TRP D 1 96  ? 42.751  28.454  59.553 1.00 40.71  ? 298 TRP D NE1 1 
ATOM   10057 C CE2 . TRP D 1 96  ? 41.693  27.655  59.893 1.00 40.93  ? 298 TRP D CE2 1 
ATOM   10058 C CE3 . TRP D 1 96  ? 39.831  27.705  61.425 1.00 41.08  ? 298 TRP D CE3 1 
ATOM   10059 C CZ2 . TRP D 1 96  ? 41.315  26.412  59.400 1.00 40.63  ? 298 TRP D CZ2 1 
ATOM   10060 C CZ3 . TRP D 1 96  ? 39.458  26.473  60.937 1.00 41.09  ? 298 TRP D CZ3 1 
ATOM   10061 C CH2 . TRP D 1 96  ? 40.196  25.838  59.934 1.00 40.89  ? 298 TRP D CH2 1 
ATOM   10062 N N   . GLN D 1 97  ? 43.883  31.109  63.895 1.00 42.99  ? 299 GLN D N   1 
ATOM   10063 C CA  . GLN D 1 97  ? 45.324  30.944  64.055 1.00 43.56  ? 299 GLN D CA  1 
ATOM   10064 C C   . GLN D 1 97  ? 45.660  30.306  65.395 1.00 45.06  ? 299 GLN D C   1 
ATOM   10065 O O   . GLN D 1 97  ? 46.523  29.424  65.471 1.00 45.33  ? 299 GLN D O   1 
ATOM   10066 C CB  . GLN D 1 97  ? 46.023  32.294  63.912 1.00 42.11  ? 299 GLN D CB  1 
ATOM   10067 C CG  . GLN D 1 97  ? 47.528  32.218  63.965 1.00 41.97  ? 299 GLN D CG  1 
ATOM   10068 C CD  . GLN D 1 97  ? 48.179  33.552  63.687 1.00 43.53  ? 299 GLN D CD  1 
ATOM   10069 O OE1 . GLN D 1 97  ? 47.506  34.524  63.354 1.00 44.96  ? 299 GLN D OE1 1 
ATOM   10070 N NE2 . GLN D 1 97  ? 49.494  33.608  63.827 1.00 43.48  ? 299 GLN D NE2 1 
ATOM   10071 N N   . ARG D 1 98  ? 44.992  30.739  66.466 1.00 46.64  ? 300 ARG D N   1 
ATOM   10072 C CA  . ARG D 1 98  ? 45.178  30.093  67.761 1.00 49.19  ? 300 ARG D CA  1 
ATOM   10073 C C   . ARG D 1 98  ? 44.783  28.623  67.696 1.00 47.77  ? 300 ARG D C   1 
ATOM   10074 O O   . ARG D 1 98  ? 45.309  27.794  68.447 1.00 47.76  ? 300 ARG D O   1 
ATOM   10075 C CB  . ARG D 1 98  ? 44.361  30.820  68.832 1.00 41.34  ? 300 ARG D CB  1 
ATOM   10076 C CG  . ARG D 1 98  ? 44.540  30.271  70.238 1.00 49.80  ? 300 ARG D CG  1 
ATOM   10077 C CD  . ARG D 1 98  ? 43.799  31.096  71.280 1.00 58.32  ? 300 ARG D CD  1 
ATOM   10078 N NE  . ARG D 1 98  ? 44.313  32.456  71.406 1.00 68.25  ? 300 ARG D NE  1 
ATOM   10079 C CZ  . ARG D 1 98  ? 43.680  33.538  70.964 1.00 72.46  ? 300 ARG D CZ  1 
ATOM   10080 N NH1 . ARG D 1 98  ? 42.503  33.424  70.366 1.00 72.95  ? 300 ARG D NH1 1 
ATOM   10081 N NH2 . ARG D 1 98  ? 44.222  34.737  71.123 1.00 72.80  ? 300 ARG D NH2 1 
ATOM   10082 N N   . LEU D 1 99  ? 43.864  28.285  66.790 1.00 47.32  ? 301 LEU D N   1 
ATOM   10083 C CA  . LEU D 1 99  ? 43.379  26.913  66.680 1.00 45.87  ? 301 LEU D CA  1 
ATOM   10084 C C   . LEU D 1 99  ? 44.444  25.985  66.111 1.00 46.49  ? 301 LEU D C   1 
ATOM   10085 O O   . LEU D 1 99  ? 44.745  24.937  66.692 1.00 46.64  ? 301 LEU D O   1 
ATOM   10086 C CB  . LEU D 1 99  ? 42.128  26.880  65.807 1.00 46.59  ? 301 LEU D CB  1 
ATOM   10087 C CG  . LEU D 1 99  ? 41.553  25.501  65.490 1.00 46.42  ? 301 LEU D CG  1 
ATOM   10088 C CD1 . LEU D 1 99  ? 41.088  24.822  66.756 1.00 45.76  ? 301 LEU D CD1 1 
ATOM   10089 C CD2 . LEU D 1 99  ? 40.418  25.616  64.491 1.00 46.56  ? 301 LEU D CD2 1 
ATOM   10090 N N   . ILE D 1 100 ? 45.025  26.353  64.969 1.00 46.39  ? 302 ILE D N   1 
ATOM   10091 C CA  . ILE D 1 100 ? 45.812  25.390  64.206 1.00 45.97  ? 302 ILE D CA  1 
ATOM   10092 C C   . ILE D 1 100 ? 47.206  25.220  64.798 1.00 45.63  ? 302 ILE D C   1 
ATOM   10093 O O   . ILE D 1 100 ? 47.821  24.156  64.660 1.00 46.88  ? 302 ILE D O   1 
ATOM   10094 C CB  . ILE D 1 100 ? 45.871  25.804  62.726 1.00 41.55  ? 302 ILE D CB  1 
ATOM   10095 C CG1 . ILE D 1 100 ? 46.574  27.150  62.573 1.00 43.81  ? 302 ILE D CG1 1 
ATOM   10096 C CG2 . ILE D 1 100 ? 44.470  25.870  62.139 1.00 44.18  ? 302 ILE D CG2 1 
ATOM   10097 C CD1 . ILE D 1 100 ? 46.837  27.524  61.141 1.00 47.72  ? 302 ILE D CD1 1 
ATOM   10098 N N   . ASN D 1 101 ? 47.731  26.249  65.466 1.00 47.10  ? 303 ASN D N   1 
ATOM   10099 C CA  . ASN D 1 101 ? 49.117  26.174  65.922 1.00 46.89  ? 303 ASN D CA  1 
ATOM   10100 C C   . ASN D 1 101 ? 49.258  25.312  67.171 1.00 47.39  ? 303 ASN D C   1 
ATOM   10101 O O   . ASN D 1 101 ? 50.199  24.518  67.278 1.00 47.73  ? 303 ASN D O   1 
ATOM   10102 C CB  . ASN D 1 101 ? 49.677  27.574  66.174 1.00 45.09  ? 303 ASN D CB  1 
ATOM   10103 C CG  . ASN D 1 101 ? 49.948  28.332  64.892 1.00 45.23  ? 303 ASN D CG  1 
ATOM   10104 O OD1 . ASN D 1 101 ? 50.107  27.736  63.831 1.00 44.36  ? 303 ASN D OD1 1 
ATOM   10105 N ND2 . ASN D 1 101 ? 50.020  29.651  64.987 1.00 43.77  ? 303 ASN D ND2 1 
ATOM   10106 N N   . ASN D 1 102 ? 48.348  25.454  68.127 1.00 49.21  ? 304 ASN D N   1 
ATOM   10107 C CA  . ASN D 1 102 ? 48.509  24.825  69.429 1.00 49.68  ? 304 ASN D CA  1 
ATOM   10108 C C   . ASN D 1 102 ? 47.753  23.512  69.583 1.00 50.04  ? 304 ASN D C   1 
ATOM   10109 O O   . ASN D 1 102 ? 47.854  22.885  70.641 1.00 50.46  ? 304 ASN D O   1 
ATOM   10110 C CB  . ASN D 1 102 ? 48.078  25.796  70.530 1.00 52.36  ? 304 ASN D CB  1 
ATOM   10111 C CG  . ASN D 1 102 ? 49.009  26.979  70.651 1.00 55.35  ? 304 ASN D CG  1 
ATOM   10112 O OD1 . ASN D 1 102 ? 50.169  26.912  70.248 1.00 58.78  ? 304 ASN D OD1 1 
ATOM   10113 N ND2 . ASN D 1 102 ? 48.507  28.073  71.207 1.00 55.70  ? 304 ASN D ND2 1 
ATOM   10114 N N   . ASN D 1 103 ? 47.010  23.071  68.572 1.00 48.61  ? 305 ASN D N   1 
ATOM   10115 C CA  . ASN D 1 103 ? 46.122  21.928  68.724 1.00 48.46  ? 305 ASN D CA  1 
ATOM   10116 C C   . ASN D 1 103 ? 46.333  20.911  67.612 1.00 48.50  ? 305 ASN D C   1 
ATOM   10117 O O   . ASN D 1 103 ? 46.509  21.268  66.444 1.00 48.71  ? 305 ASN D O   1 
ATOM   10118 C CB  . ASN D 1 103 ? 44.660  22.374  68.734 1.00 48.73  ? 305 ASN D CB  1 
ATOM   10119 C CG  . ASN D 1 103 ? 44.317  23.198  69.954 1.00 49.51  ? 305 ASN D CG  1 
ATOM   10120 O OD1 . ASN D 1 103 ? 44.130  22.665  71.044 1.00 52.26  ? 305 ASN D OD1 1 
ATOM   10121 N ND2 . ASN D 1 103 ? 44.240  24.510  69.777 1.00 49.91  ? 305 ASN D ND2 1 
ATOM   10122 N N   . TRP D 1 104 ? 46.310  19.632  67.991 1.00 47.47  ? 306 TRP D N   1 
ATOM   10123 C CA  . TRP D 1 104 ? 46.377  18.539  67.030 1.00 47.96  ? 306 TRP D CA  1 
ATOM   10124 C C   . TRP D 1 104 ? 45.035  18.187  66.410 1.00 47.86  ? 306 TRP D C   1 
ATOM   10125 O O   . TRP D 1 104 ? 45.010  17.519  65.372 1.00 48.97  ? 306 TRP D O   1 
ATOM   10126 C CB  . TRP D 1 104 ? 46.946  17.278  67.686 1.00 45.45  ? 306 TRP D CB  1 
ATOM   10127 C CG  . TRP D 1 104 ? 48.416  17.298  67.905 1.00 48.47  ? 306 TRP D CG  1 
ATOM   10128 C CD1 . TRP D 1 104 ? 49.301  18.236  67.468 1.00 49.67  ? 306 TRP D CD1 1 
ATOM   10129 C CD2 . TRP D 1 104 ? 49.182  16.323  68.617 1.00 50.80  ? 306 TRP D CD2 1 
ATOM   10130 N NE1 . TRP D 1 104 ? 50.574  17.905  67.863 1.00 50.62  ? 306 TRP D NE1 1 
ATOM   10131 C CE2 . TRP D 1 104 ? 50.526  16.734  68.572 1.00 51.35  ? 306 TRP D CE2 1 
ATOM   10132 C CE3 . TRP D 1 104 ? 48.860  15.143  69.291 1.00 50.17  ? 306 TRP D CE3 1 
ATOM   10133 C CZ2 . TRP D 1 104 ? 51.548  16.007  69.175 1.00 51.83  ? 306 TRP D CZ2 1 
ATOM   10134 C CZ3 . TRP D 1 104 ? 49.874  14.424  69.887 1.00 50.42  ? 306 TRP D CZ3 1 
ATOM   10135 C CH2 . TRP D 1 104 ? 51.201  14.857  69.826 1.00 52.00  ? 306 TRP D CH2 1 
ATOM   10136 N N   . GLY D 1 105 ? 43.927  18.606  67.008 1.00 48.96  ? 307 GLY D N   1 
ATOM   10137 C CA  . GLY D 1 105 ? 42.635  18.229  66.465 1.00 48.84  ? 307 GLY D CA  1 
ATOM   10138 C C   . GLY D 1 105 ? 41.504  18.948  67.162 1.00 48.51  ? 307 GLY D C   1 
ATOM   10139 O O   . GLY D 1 105 ? 41.648  19.452  68.278 1.00 47.71  ? 307 GLY D O   1 
ATOM   10140 N N   . PHE D 1 106 ? 40.364  18.975  66.479 1.00 44.04  ? 308 PHE D N   1 
ATOM   10141 C CA  . PHE D 1 106 ? 39.169  19.626  66.995 1.00 44.99  ? 308 PHE D CA  1 
ATOM   10142 C C   . PHE D 1 106 ? 37.952  18.987  66.343 1.00 45.26  ? 308 PHE D C   1 
ATOM   10143 O O   . PHE D 1 106 ? 38.060  18.283  65.339 1.00 45.36  ? 308 PHE D O   1 
ATOM   10144 C CB  . PHE D 1 106 ? 39.197  21.136  66.746 1.00 43.11  ? 308 PHE D CB  1 
ATOM   10145 C CG  . PHE D 1 106 ? 39.228  21.512  65.296 1.00 44.31  ? 308 PHE D CG  1 
ATOM   10146 C CD1 . PHE D 1 106 ? 38.054  21.750  64.602 1.00 44.74  ? 308 PHE D CD1 1 
ATOM   10147 C CD2 . PHE D 1 106 ? 40.429  21.620  64.625 1.00 46.08  ? 308 PHE D CD2 1 
ATOM   10148 C CE1 . PHE D 1 106 ? 38.082  22.095  63.271 1.00 46.07  ? 308 PHE D CE1 1 
ATOM   10149 C CE2 . PHE D 1 106 ? 40.461  21.964  63.292 1.00 46.79  ? 308 PHE D CE2 1 
ATOM   10150 C CZ  . PHE D 1 106 ? 39.286  22.201  62.616 1.00 45.80  ? 308 PHE D CZ  1 
ATOM   10151 N N   . ARG D 1 107 ? 36.786  19.274  66.911 1.00 45.79  ? 309 ARG D N   1 
ATOM   10152 C CA  . ARG D 1 107 ? 35.523  18.725  66.435 1.00 46.08  ? 309 ARG D CA  1 
ATOM   10153 C C   . ARG D 1 107 ? 34.374  19.358  67.205 1.00 45.48  ? 309 ARG D C   1 
ATOM   10154 O O   . ARG D 1 107 ? 34.534  19.723  68.376 1.00 46.04  ? 309 ARG D O   1 
ATOM   10155 C CB  . ARG D 1 107 ? 35.482  17.206  66.599 1.00 40.34  ? 309 ARG D CB  1 
ATOM   10156 C CG  . ARG D 1 107 ? 35.576  16.734  68.033 1.00 41.82  ? 309 ARG D CG  1 
ATOM   10157 C CD  . ARG D 1 107 ? 35.418  15.236  68.097 1.00 45.15  ? 309 ARG D CD  1 
ATOM   10158 N NE  . ARG D 1 107 ? 35.428  14.732  69.463 1.00 49.88  ? 309 ARG D NE  1 
ATOM   10159 C CZ  . ARG D 1 107 ? 35.370  13.444  69.775 1.00 52.43  ? 309 ARG D CZ  1 
ATOM   10160 N NH1 . ARG D 1 107 ? 35.303  12.533  68.816 1.00 53.73  ? 309 ARG D NH1 1 
ATOM   10161 N NH2 . ARG D 1 107 ? 35.383  13.065  71.044 1.00 53.53  ? 309 ARG D NH2 1 
ATOM   10162 N N   . PRO D 1 108 ? 33.216  19.534  66.577 1.00 44.49  ? 310 PRO D N   1 
ATOM   10163 C CA  . PRO D 1 108 ? 32.099  20.187  67.259 1.00 44.48  ? 310 PRO D CA  1 
ATOM   10164 C C   . PRO D 1 108 ? 31.465  19.278  68.293 1.00 45.90  ? 310 PRO D C   1 
ATOM   10165 O O   . PRO D 1 108 ? 31.607  18.055  68.258 1.00 45.20  ? 310 PRO D O   1 
ATOM   10166 C CB  . PRO D 1 108 ? 31.123  20.485  66.118 1.00 42.93  ? 310 PRO D CB  1 
ATOM   10167 C CG  . PRO D 1 108 ? 31.406  19.426  65.118 1.00 41.47  ? 310 PRO D CG  1 
ATOM   10168 C CD  . PRO D 1 108 ? 32.873  19.159  65.194 1.00 41.67  ? 310 PRO D CD  1 
ATOM   10169 N N   . LYS D 1 109 ? 30.703  19.887  69.193 1.00 45.10  ? 311 LYS D N   1 
ATOM   10170 C CA  . LYS D 1 109 ? 30.019  19.147  70.242 1.00 47.42  ? 311 LYS D CA  1 
ATOM   10171 C C   . LYS D 1 109 ? 28.538  19.486  70.307 1.00 47.30  ? 311 LYS D C   1 
ATOM   10172 O O   . LYS D 1 109 ? 27.691  18.611  70.213 1.00 47.17  ? 311 LYS D O   1 
ATOM   10173 C CB  . LYS D 1 109 ? 30.667  19.423  71.597 1.00 44.14  ? 311 LYS D CB  1 
ATOM   10174 C CG  . LYS D 1 109 ? 32.167  19.203  71.619 1.00 50.97  ? 311 LYS D CG  1 
ATOM   10175 C CD  . LYS D 1 109 ? 32.517  17.752  71.336 1.00 58.10  ? 311 LYS D CD  1 
ATOM   10176 C CE  . LYS D 1 109 ? 31.959  16.830  72.404 1.00 63.59  ? 311 LYS D CE  1 
ATOM   10177 N NZ  . LYS D 1 109 ? 32.539  15.466  72.290 1.00 61.55  ? 311 LYS D NZ  1 
ATOM   10178 N N   . ARG D 1 110 ? 28.235  20.765  70.472 1.00 45.73  ? 312 ARG D N   1 
ATOM   10179 C CA  . ARG D 1 110 ? 26.859  21.225  70.576 1.00 46.89  ? 312 ARG D CA  1 
ATOM   10180 C C   . ARG D 1 110 ? 26.626  22.437  69.700 1.00 45.72  ? 312 ARG D C   1 
ATOM   10181 O O   . ARG D 1 110 ? 27.545  23.206  69.443 1.00 45.46  ? 312 ARG D O   1 
ATOM   10182 C CB  . ARG D 1 110 ? 26.548  21.600  72.021 1.00 46.61  ? 312 ARG D CB  1 
ATOM   10183 C CG  . ARG D 1 110 ? 26.691  20.450  72.993 1.00 56.01  ? 312 ARG D CG  1 
ATOM   10184 C CD  . ARG D 1 110 ? 27.076  20.940  74.375 1.00 64.93  ? 312 ARG D CD  1 
ATOM   10185 N NE  . ARG D 1 110 ? 27.122  19.871  75.372 1.00 74.71  ? 312 ARG D NE  1 
ATOM   10186 C CZ  . ARG D 1 110 ? 27.530  18.623  75.149 1.00 79.67  ? 312 ARG D CZ  1 
ATOM   10187 N NH1 . ARG D 1 110 ? 27.966  18.248  73.956 1.00 81.65  ? 312 ARG D NH1 1 
ATOM   10188 N NH2 . ARG D 1 110 ? 27.518  17.742  76.141 1.00 80.83  ? 312 ARG D NH2 1 
ATOM   10189 N N   . LEU D 1 111 ? 25.395  22.599  69.237 1.00 43.06  ? 313 LEU D N   1 
ATOM   10190 C CA  . LEU D 1 111 ? 25.041  23.732  68.401 1.00 41.79  ? 313 LEU D CA  1 
ATOM   10191 C C   . LEU D 1 111 ? 23.845  24.476  68.984 1.00 42.08  ? 313 LEU D C   1 
ATOM   10192 O O   . LEU D 1 111 ? 22.833  23.868  69.294 1.00 41.49  ? 313 LEU D O   1 
ATOM   10193 C CB  . LEU D 1 111 ? 24.724  23.240  66.989 1.00 39.89  ? 313 LEU D CB  1 
ATOM   10194 C CG  . LEU D 1 111 ? 24.164  24.219  65.960 1.00 39.82  ? 313 LEU D CG  1 
ATOM   10195 C CD1 . LEU D 1 111 ? 22.759  24.658  66.334 1.00 41.10  ? 313 LEU D CD1 1 
ATOM   10196 C CD2 . LEU D 1 111 ? 25.091  25.412  65.825 1.00 45.02  ? 313 LEU D CD2 1 
ATOM   10197 N N   . ASN D 1 112 ? 23.954  25.788  69.136 1.00 42.37  ? 314 ASN D N   1 
ATOM   10198 C CA  . ASN D 1 112 ? 22.839  26.575  69.651 1.00 42.92  ? 314 ASN D CA  1 
ATOM   10199 C C   . ASN D 1 112 ? 22.461  27.627  68.614 1.00 41.53  ? 314 ASN D C   1 
ATOM   10200 O O   . ASN D 1 112 ? 23.327  28.340  68.123 1.00 43.21  ? 314 ASN D O   1 
ATOM   10201 C CB  . ASN D 1 112 ? 23.200  27.214  70.984 1.00 41.93  ? 314 ASN D CB  1 
ATOM   10202 C CG  . ASN D 1 112 ? 21.981  27.616  71.776 1.00 48.10  ? 314 ASN D CG  1 
ATOM   10203 O OD1 . ASN D 1 112 ? 20.962  27.992  71.207 1.00 51.11  ? 314 ASN D OD1 1 
ATOM   10204 N ND2 . ASN D 1 112 ? 22.076  27.532  73.095 1.00 52.17  ? 314 ASN D ND2 1 
ATOM   10205 N N   . PHE D 1 113 ? 21.177  27.736  68.288 1.00 42.21  ? 315 PHE D N   1 
ATOM   10206 C CA  . PHE D 1 113 ? 20.738  28.671  67.253 1.00 40.78  ? 315 PHE D CA  1 
ATOM   10207 C C   . PHE D 1 113 ? 19.586  29.582  67.667 1.00 41.12  ? 315 PHE D C   1 
ATOM   10208 O O   . PHE D 1 113 ? 18.510  29.105  68.002 1.00 41.13  ? 315 PHE D O   1 
ATOM   10209 C CB  . PHE D 1 113 ? 20.349  27.869  66.009 1.00 37.85  ? 315 PHE D CB  1 
ATOM   10210 C CG  . PHE D 1 113 ? 19.785  28.696  64.896 1.00 37.25  ? 315 PHE D CG  1 
ATOM   10211 C CD1 . PHE D 1 113 ? 20.574  29.068  63.828 1.00 37.80  ? 315 PHE D CD1 1 
ATOM   10212 C CD2 . PHE D 1 113 ? 18.463  29.092  64.915 1.00 36.84  ? 315 PHE D CD2 1 
ATOM   10213 C CE1 . PHE D 1 113 ? 20.057  29.827  62.801 1.00 37.80  ? 315 PHE D CE1 1 
ATOM   10214 C CE2 . PHE D 1 113 ? 17.937  29.849  63.890 1.00 35.92  ? 315 PHE D CE2 1 
ATOM   10215 C CZ  . PHE D 1 113 ? 18.736  30.218  62.831 1.00 37.39  ? 315 PHE D CZ  1 
ATOM   10216 N N   . LYS D 1 114 ? 19.801  30.894  67.614 1.00 40.61  ? 316 LYS D N   1 
ATOM   10217 C CA  . LYS D 1 114 ? 18.772  31.847  68.002 1.00 41.43  ? 316 LYS D CA  1 
ATOM   10218 C C   . LYS D 1 114 ? 18.412  32.730  66.819 1.00 41.10  ? 316 LYS D C   1 
ATOM   10219 O O   . LYS D 1 114 ? 19.236  32.985  65.938 1.00 42.52  ? 316 LYS D O   1 
ATOM   10220 C CB  . LYS D 1 114 ? 19.213  32.738  69.171 1.00 44.08  ? 316 LYS D CB  1 
ATOM   10221 C CG  . LYS D 1 114 ? 19.402  32.032  70.495 1.00 46.29  ? 316 LYS D CG  1 
ATOM   10222 C CD  . LYS D 1 114 ? 19.884  33.016  71.550 1.00 49.08  ? 316 LYS D CD  1 
ATOM   10223 C CE  . LYS D 1 114 ? 20.058  32.355  72.903 1.00 50.95  ? 316 LYS D CE  1 
ATOM   10224 N NZ  . LYS D 1 114 ? 20.573  33.315  73.915 1.00 54.99  ? 316 LYS D NZ  1 
ATOM   10225 N N   . LEU D 1 115 ? 17.166  33.196  66.810 1.00 43.56  ? 317 LEU D N   1 
ATOM   10226 C CA  . LEU D 1 115 ? 16.690  34.134  65.802 1.00 42.92  ? 317 LEU D CA  1 
ATOM   10227 C C   . LEU D 1 115 ? 15.862  35.195  66.510 1.00 43.20  ? 317 LEU D C   1 
ATOM   10228 O O   . LEU D 1 115 ? 14.817  34.876  67.081 1.00 43.87  ? 317 LEU D O   1 
ATOM   10229 C CB  . LEU D 1 115 ? 15.863  33.400  64.744 1.00 38.80  ? 317 LEU D CB  1 
ATOM   10230 C CG  . LEU D 1 115 ? 15.283  34.179  63.574 1.00 41.90  ? 317 LEU D CG  1 
ATOM   10231 C CD1 . LEU D 1 115 ? 16.402  34.739  62.735 1.00 42.71  ? 317 LEU D CD1 1 
ATOM   10232 C CD2 . LEU D 1 115 ? 14.399  33.274  62.742 1.00 43.00  ? 317 LEU D CD2 1 
ATOM   10233 N N   . PHE D 1 116 ? 16.305  36.450  66.465 1.00 45.03  ? 318 PHE D N   1 
ATOM   10234 C CA  . PHE D 1 116 ? 15.672  37.486  67.275 1.00 45.58  ? 318 PHE D CA  1 
ATOM   10235 C C   . PHE D 1 116 ? 15.690  38.813  66.524 1.00 46.67  ? 318 PHE D C   1 
ATOM   10236 O O   . PHE D 1 116 ? 16.248  38.926  65.430 1.00 47.96  ? 318 PHE D O   1 
ATOM   10237 C CB  . PHE D 1 116 ? 16.364  37.605  68.634 1.00 47.62  ? 318 PHE D CB  1 
ATOM   10238 C CG  . PHE D 1 116 ? 17.823  37.932  68.542 1.00 48.53  ? 318 PHE D CG  1 
ATOM   10239 C CD1 . PHE D 1 116 ? 18.253  39.246  68.542 1.00 48.46  ? 318 PHE D CD1 1 
ATOM   10240 C CD2 . PHE D 1 116 ? 18.765  36.925  68.448 1.00 48.71  ? 318 PHE D CD2 1 
ATOM   10241 C CE1 . PHE D 1 116 ? 19.591  39.547  68.457 1.00 47.83  ? 318 PHE D CE1 1 
ATOM   10242 C CE2 . PHE D 1 116 ? 20.106  37.220  68.359 1.00 48.93  ? 318 PHE D CE2 1 
ATOM   10243 C CZ  . PHE D 1 116 ? 20.519  38.532  68.360 1.00 49.23  ? 318 PHE D CZ  1 
ATOM   10244 N N   . ASN D 1 117 ? 15.082  39.826  67.149 1.00 51.19  ? 319 ASN D N   1 
ATOM   10245 C CA  . ASN D 1 117 ? 14.954  41.176  66.592 1.00 51.61  ? 319 ASN D CA  1 
ATOM   10246 C C   . ASN D 1 117 ? 14.404  41.146  65.169 1.00 52.12  ? 319 ASN D C   1 
ATOM   10247 O O   . ASN D 1 117 ? 14.872  41.856  64.276 1.00 54.21  ? 319 ASN D O   1 
ATOM   10248 C CB  . ASN D 1 117 ? 16.282  41.931  66.650 1.00 52.29  ? 319 ASN D CB  1 
ATOM   10249 C CG  . ASN D 1 117 ? 16.631  42.381  68.051 1.00 54.80  ? 319 ASN D CG  1 
ATOM   10250 O OD1 . ASN D 1 117 ? 15.757  42.512  68.906 1.00 53.98  ? 319 ASN D OD1 1 
ATOM   10251 N ND2 . ASN D 1 117 ? 17.911  42.636  68.290 1.00 56.29  ? 319 ASN D ND2 1 
ATOM   10252 N N   . ILE D 1 118 ? 13.384  40.312  64.968 1.00 49.66  ? 320 ILE D N   1 
ATOM   10253 C CA  . ILE D 1 118 ? 12.762  40.189  63.660 1.00 50.07  ? 320 ILE D CA  1 
ATOM   10254 C C   . ILE D 1 118 ? 12.107  41.509  63.284 1.00 51.07  ? 320 ILE D C   1 
ATOM   10255 O O   . ILE D 1 118 ? 11.341  42.089  64.065 1.00 52.18  ? 320 ILE D O   1 
ATOM   10256 C CB  . ILE D 1 118 ? 11.732  39.047  63.663 1.00 47.21  ? 320 ILE D CB  1 
ATOM   10257 C CG1 . ILE D 1 118 ? 12.377  37.745  64.130 1.00 46.60  ? 320 ILE D CG1 1 
ATOM   10258 C CG2 . ILE D 1 118 ? 11.128  38.871  62.281 1.00 47.59  ? 320 ILE D CG2 1 
ATOM   10259 C CD1 . ILE D 1 118 ? 13.529  37.314  63.287 1.00 49.09  ? 320 ILE D CD1 1 
ATOM   10260 N N   . GLN D 1 119 ? 12.416  42.001  62.088 1.00 47.98  ? 321 GLN D N   1 
ATOM   10261 C CA  . GLN D 1 119 ? 11.763  43.187  61.544 1.00 49.12  ? 321 GLN D CA  1 
ATOM   10262 C C   . GLN D 1 119 ? 11.159  42.805  60.206 1.00 49.35  ? 321 GLN D C   1 
ATOM   10263 O O   . GLN D 1 119 ? 11.671  41.906  59.536 1.00 50.18  ? 321 GLN D O   1 
ATOM   10264 C CB  . GLN D 1 119 ? 12.744  44.349  61.376 1.00 48.81  ? 321 GLN D CB  1 
ATOM   10265 C CG  . GLN D 1 119 ? 13.326  44.869  62.672 1.00 51.10  ? 321 GLN D CG  1 
ATOM   10266 C CD  . GLN D 1 119 ? 14.302  46.001  62.448 1.00 53.41  ? 321 GLN D CD  1 
ATOM   10267 O OE1 . GLN D 1 119 ? 14.858  46.148  61.362 1.00 52.40  ? 321 GLN D OE1 1 
ATOM   10268 N NE2 . GLN D 1 119 ? 14.523  46.804  63.480 1.00 52.56  ? 321 GLN D NE2 1 
ATOM   10269 N N   . VAL D 1 120 ? 10.074  43.471  59.823 1.00 47.90  ? 322 VAL D N   1 
ATOM   10270 C CA  . VAL D 1 120 ? 9.419   43.250  58.540 1.00 48.38  ? 322 VAL D CA  1 
ATOM   10271 C C   . VAL D 1 120 ? 9.090   44.608  57.938 1.00 49.02  ? 322 VAL D C   1 
ATOM   10272 O O   . VAL D 1 120 ? 8.549   45.482  58.625 1.00 49.23  ? 322 VAL D O   1 
ATOM   10273 C CB  . VAL D 1 120 ? 8.150   42.393  58.689 1.00 47.94  ? 322 VAL D CB  1 
ATOM   10274 C CG1 . VAL D 1 120 ? 7.471   42.233  57.347 1.00 47.73  ? 322 VAL D CG1 1 
ATOM   10275 C CG2 . VAL D 1 120 ? 8.483   41.035  59.275 1.00 46.20  ? 322 VAL D CG2 1 
ATOM   10276 N N   . LYS D 1 121 ? 9.413   44.786  56.660 1.00 46.46  ? 323 LYS D N   1 
ATOM   10277 C CA  . LYS D 1 121 ? 9.199   46.048  55.968 1.00 48.32  ? 323 LYS D CA  1 
ATOM   10278 C C   . LYS D 1 121 ? 8.296   45.834  54.763 1.00 49.93  ? 323 LYS D C   1 
ATOM   10279 O O   . LYS D 1 121 ? 8.406   44.821  54.066 1.00 50.08  ? 323 LYS D O   1 
ATOM   10280 C CB  . LYS D 1 121 ? 10.524  46.658  55.507 1.00 45.59  ? 323 LYS D CB  1 
ATOM   10281 C CG  . LYS D 1 121 ? 11.515  46.921  56.621 1.00 46.81  ? 323 LYS D CG  1 
ATOM   10282 C CD  . LYS D 1 121 ? 11.034  47.993  57.566 1.00 48.80  ? 323 LYS D CD  1 
ATOM   10283 C CE  . LYS D 1 121 ? 12.050  48.231  58.668 1.00 49.63  ? 323 LYS D CE  1 
ATOM   10284 N NZ  . LYS D 1 121 ? 13.330  48.779  58.146 1.00 51.40  ? 323 LYS D NZ  1 
ATOM   10285 N N   . GLU D 1 122 ? 7.409   46.793  54.518 1.00 49.77  ? 324 GLU D N   1 
ATOM   10286 C CA  . GLU D 1 122 ? 6.565   46.805  53.332 1.00 53.89  ? 324 GLU D CA  1 
ATOM   10287 C C   . GLU D 1 122 ? 7.066   47.877  52.373 1.00 53.95  ? 324 GLU D C   1 
ATOM   10288 O O   . GLU D 1 122 ? 7.422   48.981  52.796 1.00 54.23  ? 324 GLU D O   1 
ATOM   10289 C CB  . GLU D 1 122 ? 5.097   47.044  53.699 1.00 50.92  ? 324 GLU D CB  1 
ATOM   10290 C CG  . GLU D 1 122 ? 4.817   48.362  54.400 1.00 61.52  ? 324 GLU D CG  1 
ATOM   10291 C CD  . GLU D 1 122 ? 3.363   48.513  54.805 1.00 68.20  ? 324 GLU D CD  1 
ATOM   10292 O OE1 . GLU D 1 122 ? 2.509   47.780  54.261 1.00 71.40  ? 324 GLU D OE1 1 
ATOM   10293 O OE2 . GLU D 1 122 ? 3.072   49.364  55.671 1.00 70.67  ? 324 GLU D OE2 1 
ATOM   10294 N N   . VAL D 1 123 ? 7.101   47.546  51.087 1.00 56.17  ? 325 VAL D N   1 
ATOM   10295 C CA  . VAL D 1 123 ? 7.635   48.427  50.056 1.00 57.84  ? 325 VAL D CA  1 
ATOM   10296 C C   . VAL D 1 123 ? 6.476   48.955  49.224 1.00 60.29  ? 325 VAL D C   1 
ATOM   10297 O O   . VAL D 1 123 ? 5.830   48.195  48.492 1.00 59.87  ? 325 VAL D O   1 
ATOM   10298 C CB  . VAL D 1 123 ? 8.655   47.696  49.171 1.00 58.78  ? 325 VAL D CB  1 
ATOM   10299 C CG1 . VAL D 1 123 ? 9.122   48.602  48.050 1.00 57.62  ? 325 VAL D CG1 1 
ATOM   10300 C CG2 . VAL D 1 123 ? 9.827   47.210  50.000 1.00 58.11  ? 325 VAL D CG2 1 
ATOM   10301 N N   . THR D 1 124 ? 6.214   50.255  49.326 1.00 63.72  ? 326 THR D N   1 
ATOM   10302 C CA  . THR D 1 124 ? 5.162   50.916  48.560 1.00 68.05  ? 326 THR D CA  1 
ATOM   10303 C C   . THR D 1 124 ? 5.822   51.758  47.476 1.00 71.25  ? 326 THR D C   1 
ATOM   10304 O O   . THR D 1 124 ? 6.465   52.770  47.775 1.00 71.15  ? 326 THR D O   1 
ATOM   10305 C CB  . THR D 1 124 ? 4.278   51.778  49.461 1.00 70.27  ? 326 THR D CB  1 
ATOM   10306 O OG1 . THR D 1 124 ? 5.079   52.768  50.116 1.00 72.08  ? 326 THR D OG1 1 
ATOM   10307 C CG2 . THR D 1 124 ? 3.591   50.921  50.508 1.00 69.66  ? 326 THR D CG2 1 
ATOM   10308 N N   . ASP D 1 125 ? 5.665   51.341  46.224 1.00 75.92  ? 327 ASP D N   1 
ATOM   10309 C CA  . ASP D 1 125 ? 6.263   52.018  45.081 1.00 80.61  ? 327 ASP D CA  1 
ATOM   10310 C C   . ASP D 1 125 ? 5.151   52.573  44.201 1.00 82.14  ? 327 ASP D C   1 
ATOM   10311 O O   . ASP D 1 125 ? 4.418   51.806  43.566 1.00 82.06  ? 327 ASP D O   1 
ATOM   10312 C CB  . ASP D 1 125 ? 7.153   51.061  44.287 1.00 78.99  ? 327 ASP D CB  1 
ATOM   10313 C CG  . ASP D 1 125 ? 7.896   51.749  43.156 1.00 83.04  ? 327 ASP D CG  1 
ATOM   10314 O OD1 . ASP D 1 125 ? 7.790   52.987  43.027 1.00 84.82  ? 327 ASP D OD1 1 
ATOM   10315 O OD2 . ASP D 1 125 ? 8.591   51.048  42.392 1.00 85.07  ? 327 ASP D OD2 1 
ATOM   10316 N N   . ASN D 1 126 ? 5.032   53.899  44.160 1.00 86.59  ? 328 ASN D N   1 
ATOM   10317 C CA  . ASN D 1 126 ? 4.070   54.576  43.296 1.00 89.38  ? 328 ASN D CA  1 
ATOM   10318 C C   . ASN D 1 126 ? 4.804   55.626  42.478 1.00 90.59  ? 328 ASN D C   1 
ATOM   10319 O O   . ASN D 1 126 ? 5.273   56.626  43.032 1.00 90.46  ? 328 ASN D O   1 
ATOM   10320 C CB  . ASN D 1 126 ? 2.946   55.221  44.113 1.00 87.55  ? 328 ASN D CB  1 
ATOM   10321 C CG  . ASN D 1 126 ? 2.004   54.200  44.719 1.00 89.51  ? 328 ASN D CG  1 
ATOM   10322 O OD1 . ASN D 1 126 ? 1.888   53.077  44.228 1.00 89.87  ? 328 ASN D OD1 1 
ATOM   10323 N ND2 . ASN D 1 126 ? 1.321   54.587  45.790 1.00 90.06  ? 328 ASN D ND2 1 
ATOM   10324 N N   . ASN D 1 127 ? 4.880   55.407  41.164 1.00 90.66  ? 329 ASN D N   1 
ATOM   10325 C CA  . ASN D 1 127 ? 5.583   56.309  40.251 1.00 92.01  ? 329 ASN D CA  1 
ATOM   10326 C C   . ASN D 1 127 ? 6.990   56.603  40.768 1.00 91.47  ? 329 ASN D C   1 
ATOM   10327 O O   . ASN D 1 127 ? 7.380   57.756  40.963 1.00 91.84  ? 329 ASN D O   1 
ATOM   10328 C CB  . ASN D 1 127 ? 4.786   57.599  40.037 1.00 91.88  ? 329 ASN D CB  1 
ATOM   10329 C CG  . ASN D 1 127 ? 5.307   58.433  38.875 1.00 94.33  ? 329 ASN D CG  1 
ATOM   10330 O OD1 . ASN D 1 127 ? 6.448   58.282  38.440 1.00 95.49  ? 329 ASN D OD1 1 
ATOM   10331 N ND2 . ASN D 1 127 ? 4.460   59.318  38.364 1.00 94.42  ? 329 ASN D ND2 1 
ATOM   10332 N N   . GLY D 1 128 ? 7.752   55.544  41.016 1.00 87.86  ? 330 GLY D N   1 
ATOM   10333 C CA  . GLY D 1 128 ? 9.031   55.695  41.669 1.00 86.08  ? 330 GLY D CA  1 
ATOM   10334 C C   . GLY D 1 128 ? 8.853   56.121  43.114 1.00 84.76  ? 330 GLY D C   1 
ATOM   10335 O O   . GLY D 1 128 ? 7.888   55.750  43.789 1.00 85.18  ? 330 GLY D O   1 
ATOM   10336 N N   . VAL D 1 129 ? 9.823   56.910  43.591 1.00 85.82  ? 331 VAL D N   1 
ATOM   10337 C CA  . VAL D 1 129 ? 9.831   57.534  44.916 1.00 82.29  ? 331 VAL D CA  1 
ATOM   10338 C C   . VAL D 1 129 ? 9.352   56.546  45.975 1.00 80.22  ? 331 VAL D C   1 
ATOM   10339 O O   . VAL D 1 129 ? 8.489   56.866  46.801 1.00 79.87  ? 331 VAL D O   1 
ATOM   10340 C CB  . VAL D 1 129 ? 9.024   58.854  44.947 1.00 83.80  ? 331 VAL D CB  1 
ATOM   10341 C CG1 . VAL D 1 129 ? 9.678   59.893  44.043 1.00 82.52  ? 331 VAL D CG1 1 
ATOM   10342 C CG2 . VAL D 1 129 ? 7.547   58.674  44.572 1.00 83.42  ? 331 VAL D CG2 1 
ATOM   10343 N N   . LYS D 1 130 ? 9.925   55.343  45.964 1.00 78.61  ? 332 LYS D N   1 
ATOM   10344 C CA  . LYS D 1 130 ? 9.446   54.267  46.818 1.00 75.13  ? 332 LYS D CA  1 
ATOM   10345 C C   . LYS D 1 130 ? 9.635   54.609  48.290 1.00 72.49  ? 332 LYS D C   1 
ATOM   10346 O O   . LYS D 1 130 ? 10.512  55.394  48.663 1.00 72.78  ? 332 LYS D O   1 
ATOM   10347 C CB  . LYS D 1 130 ? 10.175  52.966  46.480 1.00 72.38  ? 332 LYS D CB  1 
ATOM   10348 C CG  . LYS D 1 130 ? 11.677  53.044  46.664 1.00 72.85  ? 332 LYS D CG  1 
ATOM   10349 C CD  . LYS D 1 130 ? 12.345  51.733  46.306 1.00 73.29  ? 332 LYS D CD  1 
ATOM   10350 C CE  . LYS D 1 130 ? 11.987  50.645  47.298 1.00 74.11  ? 332 LYS D CE  1 
ATOM   10351 N NZ  . LYS D 1 130 ? 12.643  49.351  46.960 1.00 73.73  ? 332 LYS D NZ  1 
ATOM   10352 N N   . THR D 1 131 ? 8.797   54.007  49.129 1.00 73.17  ? 333 THR D N   1 
ATOM   10353 C CA  . THR D 1 131 ? 8.772   54.266  50.560 1.00 70.18  ? 333 THR D CA  1 
ATOM   10354 C C   . THR D 1 131 ? 8.741   52.942  51.312 1.00 67.13  ? 333 THR D C   1 
ATOM   10355 O O   . THR D 1 131 ? 8.047   52.005  50.909 1.00 67.09  ? 333 THR D O   1 
ATOM   10356 C CB  . THR D 1 131 ? 7.554   55.126  50.941 1.00 73.78  ? 333 THR D CB  1 
ATOM   10357 O OG1 . THR D 1 131 ? 7.617   56.378  50.247 1.00 74.59  ? 333 THR D OG1 1 
ATOM   10358 C CG2 . THR D 1 131 ? 7.516   55.391  52.439 1.00 73.94  ? 333 THR D CG2 1 
ATOM   10359 N N   . ILE D 1 132 ? 9.496   52.870  52.404 1.00 61.18  ? 334 ILE D N   1 
ATOM   10360 C CA  . ILE D 1 132 ? 9.593   51.674  53.229 1.00 56.98  ? 334 ILE D CA  1 
ATOM   10361 C C   . ILE D 1 132 ? 9.102   52.020  54.627 1.00 55.41  ? 334 ILE D C   1 
ATOM   10362 O O   . ILE D 1 132 ? 9.503   53.042  55.194 1.00 55.43  ? 334 ILE D O   1 
ATOM   10363 C CB  . ILE D 1 132 ? 11.033  51.131  53.263 1.00 55.03  ? 334 ILE D CB  1 
ATOM   10364 C CG1 . ILE D 1 132 ? 11.450  50.667  51.869 1.00 53.88  ? 334 ILE D CG1 1 
ATOM   10365 C CG2 . ILE D 1 132 ? 11.161  49.998  54.264 1.00 54.52  ? 334 ILE D CG2 1 
ATOM   10366 C CD1 . ILE D 1 132 ? 12.916  50.338  51.750 1.00 54.81  ? 334 ILE D CD1 1 
ATOM   10367 N N   . ALA D 1 133 ? 8.235   51.173  55.177 1.00 55.37  ? 335 ALA D N   1 
ATOM   10368 C CA  . ALA D 1 133 ? 7.637   51.422  56.479 1.00 54.58  ? 335 ALA D CA  1 
ATOM   10369 C C   . ALA D 1 133 ? 7.485   50.111  57.234 1.00 55.03  ? 335 ALA D C   1 
ATOM   10370 O O   . ALA D 1 133 ? 7.360   49.037  56.642 1.00 56.67  ? 335 ALA D O   1 
ATOM   10371 C CB  . ALA D 1 133 ? 6.276   52.115  56.352 1.00 58.52  ? 335 ALA D CB  1 
ATOM   10372 N N   . ASN D 1 134 ? 7.490   50.216  58.559 1.00 56.72  ? 336 ASN D N   1 
ATOM   10373 C CA  . ASN D 1 134 ? 7.319   49.064  59.432 1.00 57.49  ? 336 ASN D CA  1 
ATOM   10374 C C   . ASN D 1 134 ? 5.929   48.477  59.243 1.00 57.43  ? 336 ASN D C   1 
ATOM   10375 O O   . ASN D 1 134 ? 4.929   49.193  59.344 1.00 57.25  ? 336 ASN D O   1 
ATOM   10376 C CB  . ASN D 1 134 ? 7.513   49.457  60.897 1.00 59.37  ? 336 ASN D CB  1 
ATOM   10377 C CG  . ASN D 1 134 ? 8.943   49.813  61.222 1.00 61.47  ? 336 ASN D CG  1 
ATOM   10378 O OD1 . ASN D 1 134 ? 9.870   49.394  60.534 1.00 64.51  ? 336 ASN D OD1 1 
ATOM   10379 N ND2 . ASN D 1 134 ? 9.133   50.585  62.285 1.00 61.56  ? 336 ASN D ND2 1 
ATOM   10380 N N   . ASN D 1 135 ? 5.868   47.179  58.974 1.00 54.85  ? 337 ASN D N   1 
ATOM   10381 C CA  . ASN D 1 135 ? 4.617   46.437  59.026 1.00 54.75  ? 337 ASN D CA  1 
ATOM   10382 C C   . ASN D 1 135 ? 4.663   45.614  60.307 1.00 53.78  ? 337 ASN D C   1 
ATOM   10383 O O   . ASN D 1 135 ? 5.387   44.616  60.387 1.00 54.74  ? 337 ASN D O   1 
ATOM   10384 C CB  . ASN D 1 135 ? 4.442   45.559  57.790 1.00 49.63  ? 337 ASN D CB  1 
ATOM   10385 C CG  . ASN D 1 135 ? 3.050   44.973  57.682 1.00 53.64  ? 337 ASN D CG  1 
ATOM   10386 O OD1 . ASN D 1 135 ? 2.313   44.904  58.664 1.00 55.35  ? 337 ASN D OD1 1 
ATOM   10387 N ND2 . ASN D 1 135 ? 2.682   44.544  56.482 1.00 57.30  ? 337 ASN D ND2 1 
ATOM   10388 N N   . LEU D 1 136 ? 3.887   46.033  61.305 1.00 54.92  ? 338 LEU D N   1 
ATOM   10389 C CA  . LEU D 1 136 ? 4.028   45.481  62.643 1.00 53.41  ? 338 LEU D CA  1 
ATOM   10390 C C   . LEU D 1 136 ? 3.320   44.147  62.819 1.00 53.92  ? 338 LEU D C   1 
ATOM   10391 O O   . LEU D 1 136 ? 3.782   43.320  63.611 1.00 54.23  ? 338 LEU D O   1 
ATOM   10392 C CB  . LEU D 1 136 ? 3.510   46.481  63.677 1.00 57.53  ? 338 LEU D CB  1 
ATOM   10393 C CG  . LEU D 1 136 ? 4.277   47.801  63.759 1.00 56.70  ? 338 LEU D CG  1 
ATOM   10394 C CD1 . LEU D 1 136 ? 3.628   48.737  64.764 1.00 52.66  ? 338 LEU D CD1 1 
ATOM   10395 C CD2 . LEU D 1 136 ? 5.734   47.554  64.107 1.00 55.90  ? 338 LEU D CD2 1 
ATOM   10396 N N   . THR D 1 137 ? 2.220   43.918  62.108 1.00 51.71  ? 339 THR D N   1 
ATOM   10397 C CA  . THR D 1 137 ? 1.410   42.723  62.296 1.00 51.83  ? 339 THR D CA  1 
ATOM   10398 C C   . THR D 1 137 ? 1.832   41.568  61.401 1.00 50.87  ? 339 THR D C   1 
ATOM   10399 O O   . THR D 1 137 ? 1.181   40.521  61.419 1.00 51.19  ? 339 THR D O   1 
ATOM   10400 C CB  . THR D 1 137 ? -0.066  43.048  62.058 1.00 53.79  ? 339 THR D CB  1 
ATOM   10401 O OG1 . THR D 1 137 ? -0.248  43.496  60.710 1.00 56.06  ? 339 THR D OG1 1 
ATOM   10402 C CG2 . THR D 1 137 ? -0.509  44.146  63.000 1.00 53.72  ? 339 THR D CG2 1 
ATOM   10403 N N   . SER D 1 138 ? 2.895   41.728  60.622 1.00 50.89  ? 340 SER D N   1 
ATOM   10404 C CA  . SER D 1 138 ? 3.375   40.640  59.788 1.00 50.41  ? 340 SER D CA  1 
ATOM   10405 C C   . SER D 1 138 ? 4.071   39.576  60.628 1.00 49.64  ? 340 SER D C   1 
ATOM   10406 O O   . SER D 1 138 ? 4.532   39.822  61.745 1.00 49.17  ? 340 SER D O   1 
ATOM   10407 C CB  . SER D 1 138 ? 4.331   41.156  58.717 1.00 49.63  ? 340 SER D CB  1 
ATOM   10408 O OG  . SER D 1 138 ? 3.656   41.987  57.793 1.00 56.09  ? 340 SER D OG  1 
ATOM   10409 N N   . THR D 1 139 ? 4.137   38.375  60.066 1.00 43.51  ? 341 THR D N   1 
ATOM   10410 C CA  . THR D 1 139 ? 4.774   37.232  60.692 1.00 43.87  ? 341 THR D CA  1 
ATOM   10411 C C   . THR D 1 139 ? 5.830   36.667  59.755 1.00 42.92  ? 341 THR D C   1 
ATOM   10412 O O   . THR D 1 139 ? 5.777   36.856  58.538 1.00 42.59  ? 341 THR D O   1 
ATOM   10413 C CB  . THR D 1 139 ? 3.754   36.139  61.036 1.00 46.07  ? 341 THR D CB  1 
ATOM   10414 O OG1 . THR D 1 139 ? 3.070   35.735  59.845 1.00 46.70  ? 341 THR D OG1 1 
ATOM   10415 C CG2 . THR D 1 139 ? 2.740   36.644  62.044 1.00 48.86  ? 341 THR D CG2 1 
ATOM   10416 N N   . VAL D 1 140 ? 6.797   35.970  60.342 1.00 40.32  ? 342 VAL D N   1 
ATOM   10417 C CA  . VAL D 1 140 ? 7.857   35.300  59.603 1.00 39.42  ? 342 VAL D CA  1 
ATOM   10418 C C   . VAL D 1 140 ? 7.886   33.844  60.038 1.00 38.88  ? 342 VAL D C   1 
ATOM   10419 O O   . VAL D 1 140 ? 8.178   33.540  61.199 1.00 39.50  ? 342 VAL D O   1 
ATOM   10420 C CB  . VAL D 1 140 ? 9.230   35.965  59.830 1.00 37.29  ? 342 VAL D CB  1 
ATOM   10421 C CG1 . VAL D 1 140 ? 10.316  35.165  59.157 1.00 39.94  ? 342 VAL D CG1 1 
ATOM   10422 C CG2 . VAL D 1 140 ? 9.225   37.383  59.301 1.00 38.71  ? 342 VAL D CG2 1 
ATOM   10423 N N   . GLN D 1 141 ? 7.579   32.949  59.106 1.00 35.33  ? 343 GLN D N   1 
ATOM   10424 C CA  . GLN D 1 141 ? 7.512   31.522  59.378 1.00 35.08  ? 343 GLN D CA  1 
ATOM   10425 C C   . GLN D 1 141 ? 8.915   30.939  59.369 1.00 34.32  ? 343 GLN D C   1 
ATOM   10426 O O   . GLN D 1 141 ? 9.730   31.276  58.507 1.00 35.06  ? 343 GLN D O   1 
ATOM   10427 C CB  . GLN D 1 141 ? 6.645   30.804  58.344 1.00 32.62  ? 343 GLN D CB  1 
ATOM   10428 C CG  . GLN D 1 141 ? 5.212   31.267  58.330 1.00 34.89  ? 343 GLN D CG  1 
ATOM   10429 C CD  . GLN D 1 141 ? 4.385   30.552  57.292 1.00 38.75  ? 343 GLN D CD  1 
ATOM   10430 O OE1 . GLN D 1 141 ? 4.917   29.983  56.341 1.00 41.51  ? 343 GLN D OE1 1 
ATOM   10431 N NE2 . GLN D 1 141 ? 3.072   30.593  57.455 1.00 40.00  ? 343 GLN D NE2 1 
ATOM   10432 N N   . VAL D 1 142 ? 9.195   30.074  60.335 1.00 31.78  ? 344 VAL D N   1 
ATOM   10433 C CA  . VAL D 1 142 ? 10.487  29.408  60.432 1.00 31.75  ? 344 VAL D CA  1 
ATOM   10434 C C   . VAL D 1 142 ? 10.277  28.035  61.047 1.00 32.62  ? 344 VAL D C   1 
ATOM   10435 O O   . VAL D 1 142 ? 9.443   27.864  61.942 1.00 33.52  ? 344 VAL D O   1 
ATOM   10436 C CB  . VAL D 1 142 ? 11.499  30.241  61.252 1.00 33.94  ? 344 VAL D CB  1 
ATOM   10437 C CG1 . VAL D 1 142 ? 11.007  30.451  62.671 1.00 33.17  ? 344 VAL D CG1 1 
ATOM   10438 C CG2 . VAL D 1 142 ? 12.863  29.575  61.259 1.00 36.51  ? 344 VAL D CG2 1 
ATOM   10439 N N   . PHE D 1 143 ? 11.023  27.050  60.554 1.00 29.61  ? 345 PHE D N   1 
ATOM   10440 C CA  . PHE D 1 143 ? 11.029  25.734  61.170 1.00 30.04  ? 345 PHE D CA  1 
ATOM   10441 C C   . PHE D 1 143 ? 12.360  25.070  60.875 1.00 30.93  ? 345 PHE D C   1 
ATOM   10442 O O   . PHE D 1 143 ? 13.057  25.423  59.922 1.00 31.40  ? 345 PHE D O   1 
ATOM   10443 C CB  . PHE D 1 143 ? 9.880   24.845  60.674 1.00 28.40  ? 345 PHE D CB  1 
ATOM   10444 C CG  . PHE D 1 143 ? 9.998   24.420  59.234 1.00 29.06  ? 345 PHE D CG  1 
ATOM   10445 C CD1 . PHE D 1 143 ? 10.579  23.207  58.903 1.00 28.44  ? 345 PHE D CD1 1 
ATOM   10446 C CD2 . PHE D 1 143 ? 9.529   25.226  58.216 1.00 29.92  ? 345 PHE D CD2 1 
ATOM   10447 C CE1 . PHE D 1 143 ? 10.687  22.809  57.587 1.00 28.73  ? 345 PHE D CE1 1 
ATOM   10448 C CE2 . PHE D 1 143 ? 9.638   24.832  56.897 1.00 30.00  ? 345 PHE D CE2 1 
ATOM   10449 C CZ  . PHE D 1 143 ? 10.217  23.622  56.584 1.00 29.52  ? 345 PHE D CZ  1 
ATOM   10450 N N   . THR D 1 144 ? 12.705  24.106  61.712 1.00 30.27  ? 346 THR D N   1 
ATOM   10451 C CA  . THR D 1 144 ? 13.836  23.233  61.462 1.00 32.41  ? 346 THR D CA  1 
ATOM   10452 C C   . THR D 1 144 ? 13.323  21.886  60.992 1.00 34.47  ? 346 THR D C   1 
ATOM   10453 O O   . THR D 1 144 ? 12.260  21.428  61.416 1.00 34.56  ? 346 THR D O   1 
ATOM   10454 C CB  . THR D 1 144 ? 14.684  23.051  62.717 1.00 34.69  ? 346 THR D CB  1 
ATOM   10455 O OG1 . THR D 1 144 ? 13.884  22.460  63.747 1.00 37.75  ? 346 THR D OG1 1 
ATOM   10456 C CG2 . THR D 1 144 ? 15.189  24.385  63.195 1.00 34.42  ? 346 THR D CG2 1 
ATOM   10457 N N   . ASP D 1 145 ? 14.082  21.249  60.111 1.00 32.03  ? 347 ASP D N   1 
ATOM   10458 C CA  . ASP D 1 145 ? 13.763  19.887  59.708 1.00 35.43  ? 347 ASP D CA  1 
ATOM   10459 C C   . ASP D 1 145 ? 14.705  19.008  60.518 1.00 35.67  ? 347 ASP D C   1 
ATOM   10460 O O   . ASP D 1 145 ? 15.865  18.811  60.161 1.00 35.51  ? 347 ASP D O   1 
ATOM   10461 C CB  . ASP D 1 145 ? 13.952  19.716  58.205 1.00 30.15  ? 347 ASP D CB  1 
ATOM   10462 C CG  . ASP D 1 145 ? 13.476  18.373  57.703 1.00 35.71  ? 347 ASP D CG  1 
ATOM   10463 O OD1 . ASP D 1 145 ? 12.875  17.616  58.493 1.00 36.73  ? 347 ASP D OD1 1 
ATOM   10464 O OD2 . ASP D 1 145 ? 13.716  18.067  56.518 1.00 38.47  ? 347 ASP D OD2 1 
ATOM   10465 N N   . SER D 1 146 ? 14.182  18.445  61.603 1.00 35.30  ? 348 SER D N   1 
ATOM   10466 C CA  . SER D 1 146 ? 14.971  17.601  62.482 1.00 35.34  ? 348 SER D CA  1 
ATOM   10467 C C   . SER D 1 146 ? 14.752  16.120  62.232 1.00 35.81  ? 348 SER D C   1 
ATOM   10468 O O   . SER D 1 146 ? 15.448  15.296  62.832 1.00 35.75  ? 348 SER D O   1 
ATOM   10469 C CB  . SER D 1 146 ? 14.662  17.931  63.946 1.00 41.66  ? 348 SER D CB  1 
ATOM   10470 O OG  . SER D 1 146 ? 13.301  17.682  64.245 1.00 45.23  ? 348 SER D OG  1 
ATOM   10471 N N   . ASP D 1 147 ? 13.807  15.769  61.368 1.00 34.16  ? 349 ASP D N   1 
ATOM   10472 C CA  . ASP D 1 147 ? 13.626  14.403  60.912 1.00 34.60  ? 349 ASP D CA  1 
ATOM   10473 C C   . ASP D 1 147 ? 14.311  14.158  59.581 1.00 32.48  ? 349 ASP D C   1 
ATOM   10474 O O   . ASP D 1 147 ? 14.286  13.029  59.084 1.00 32.17  ? 349 ASP D O   1 
ATOM   10475 C CB  . ASP D 1 147 ? 12.136  14.079  60.797 1.00 33.15  ? 349 ASP D CB  1 
ATOM   10476 C CG  . ASP D 1 147 ? 11.441  14.049  62.139 1.00 39.02  ? 349 ASP D CG  1 
ATOM   10477 O OD1 . ASP D 1 147 ? 12.138  13.962  63.171 1.00 42.27  ? 349 ASP D OD1 1 
ATOM   10478 O OD2 . ASP D 1 147 ? 10.195  14.120  62.164 1.00 42.93  ? 349 ASP D OD2 1 
ATOM   10479 N N   . TYR D 1 148 ? 14.915  15.193  58.999 1.00 32.57  ? 350 TYR D N   1 
ATOM   10480 C CA  . TYR D 1 148 ? 15.630  15.092  57.730 1.00 30.59  ? 350 TYR D CA  1 
ATOM   10481 C C   . TYR D 1 148 ? 14.709  14.570  56.635 1.00 29.99  ? 350 TYR D C   1 
ATOM   10482 O O   . TYR D 1 148 ? 15.089  13.737  55.812 1.00 30.21  ? 350 TYR D O   1 
ATOM   10483 C CB  . TYR D 1 148 ? 16.877  14.225  57.881 1.00 30.82  ? 350 TYR D CB  1 
ATOM   10484 C CG  . TYR D 1 148 ? 17.802  14.774  58.935 1.00 30.91  ? 350 TYR D CG  1 
ATOM   10485 C CD1 . TYR D 1 148 ? 18.725  15.762  58.631 1.00 31.61  ? 350 TYR D CD1 1 
ATOM   10486 C CD2 . TYR D 1 148 ? 17.730  14.323  60.243 1.00 29.64  ? 350 TYR D CD2 1 
ATOM   10487 C CE1 . TYR D 1 148 ? 19.556  16.273  59.595 1.00 31.50  ? 350 TYR D CE1 1 
ATOM   10488 C CE2 . TYR D 1 148 ? 18.558  14.826  61.212 1.00 29.56  ? 350 TYR D CE2 1 
ATOM   10489 C CZ  . TYR D 1 148 ? 19.469  15.799  60.885 1.00 31.19  ? 350 TYR D CZ  1 
ATOM   10490 O OH  . TYR D 1 148 ? 20.295  16.299  61.861 1.00 32.88  ? 350 TYR D OH  1 
ATOM   10491 N N   . GLN D 1 149 ? 13.474  15.056  56.650 1.00 27.81  ? 351 GLN D N   1 
ATOM   10492 C CA  . GLN D 1 149 ? 12.463  14.667  55.684 1.00 27.64  ? 351 GLN D CA  1 
ATOM   10493 C C   . GLN D 1 149 ? 12.537  15.453  54.384 1.00 27.26  ? 351 GLN D C   1 
ATOM   10494 O O   . GLN D 1 149 ? 12.046  14.970  53.360 1.00 29.35  ? 351 GLN D O   1 
ATOM   10495 C CB  . GLN D 1 149 ? 11.088  14.824  56.328 1.00 26.73  ? 351 GLN D CB  1 
ATOM   10496 C CG  . GLN D 1 149 ? 10.879  13.851  57.467 1.00 27.56  ? 351 GLN D CG  1 
ATOM   10497 C CD  . GLN D 1 149 ? 9.652   14.158  58.285 1.00 29.92  ? 351 GLN D CD  1 
ATOM   10498 O OE1 . GLN D 1 149 ? 9.226   15.306  58.372 1.00 32.26  ? 351 GLN D OE1 1 
ATOM   10499 N NE2 . GLN D 1 149 ? 9.071   13.134  58.890 1.00 29.63  ? 351 GLN D NE2 1 
ATOM   10500 N N   . LEU D 1 150 ? 13.132  16.636  54.398 1.00 27.14  ? 352 LEU D N   1 
ATOM   10501 C CA  . LEU D 1 150 ? 13.359  17.420  53.193 1.00 25.79  ? 352 LEU D CA  1 
ATOM   10502 C C   . LEU D 1 150 ? 14.707  17.083  52.585 1.00 25.81  ? 352 LEU D C   1 
ATOM   10503 O O   . LEU D 1 150 ? 15.587  16.527  53.244 1.00 26.75  ? 352 LEU D O   1 
ATOM   10504 C CB  . LEU D 1 150 ? 13.278  18.908  53.515 1.00 25.63  ? 352 LEU D CB  1 
ATOM   10505 C CG  . LEU D 1 150 ? 11.893  19.474  53.792 1.00 26.31  ? 352 LEU D CG  1 
ATOM   10506 C CD1 . LEU D 1 150 ? 12.001  20.905  54.264 1.00 25.80  ? 352 LEU D CD1 1 
ATOM   10507 C CD2 . LEU D 1 150 ? 11.075  19.393  52.521 1.00 24.58  ? 352 LEU D CD2 1 
ATOM   10508 N N   . PRO D 1 151 ? 14.894  17.384  51.302 1.00 24.37  ? 353 PRO D N   1 
ATOM   10509 C CA  . PRO D 1 151 ? 16.232  17.284  50.715 1.00 23.35  ? 353 PRO D CA  1 
ATOM   10510 C C   . PRO D 1 151 ? 17.221  18.183  51.436 1.00 23.82  ? 353 PRO D C   1 
ATOM   10511 O O   . PRO D 1 151 ? 16.899  19.309  51.820 1.00 23.68  ? 353 PRO D O   1 
ATOM   10512 C CB  . PRO D 1 151 ? 16.014  17.740  49.270 1.00 19.56  ? 353 PRO D CB  1 
ATOM   10513 C CG  . PRO D 1 151 ? 14.608  17.393  48.993 1.00 19.14  ? 353 PRO D CG  1 
ATOM   10514 C CD  . PRO D 1 151 ? 13.863  17.611  50.275 1.00 19.25  ? 353 PRO D CD  1 
ATOM   10515 N N   . TYR D 1 152 ? 18.435  17.672  51.619 1.00 23.97  ? 354 TYR D N   1 
ATOM   10516 C CA  . TYR D 1 152 ? 19.490  18.390  52.322 1.00 24.56  ? 354 TYR D CA  1 
ATOM   10517 C C   . TYR D 1 152 ? 20.463  18.952  51.294 1.00 25.99  ? 354 TYR D C   1 
ATOM   10518 O O   . TYR D 1 152 ? 21.227  18.201  50.680 1.00 27.47  ? 354 TYR D O   1 
ATOM   10519 C CB  . TYR D 1 152 ? 20.213  17.464  53.298 1.00 25.30  ? 354 TYR D CB  1 
ATOM   10520 C CG  . TYR D 1 152 ? 21.234  18.149  54.173 1.00 26.30  ? 354 TYR D CG  1 
ATOM   10521 C CD1 . TYR D 1 152 ? 20.857  18.764  55.357 1.00 26.31  ? 354 TYR D CD1 1 
ATOM   10522 C CD2 . TYR D 1 152 ? 22.570  18.196  53.809 1.00 25.77  ? 354 TYR D CD2 1 
ATOM   10523 C CE1 . TYR D 1 152 ? 21.785  19.390  56.164 1.00 27.44  ? 354 TYR D CE1 1 
ATOM   10524 C CE2 . TYR D 1 152 ? 23.504  18.822  54.606 1.00 27.07  ? 354 TYR D CE2 1 
ATOM   10525 C CZ  . TYR D 1 152 ? 23.106  19.416  55.782 1.00 28.78  ? 354 TYR D CZ  1 
ATOM   10526 O OH  . TYR D 1 152 ? 24.037  20.044  56.575 1.00 29.62  ? 354 TYR D OH  1 
ATOM   10527 N N   . VAL D 1 153 ? 20.431  20.268  51.108 1.00 25.70  ? 355 VAL D N   1 
ATOM   10528 C CA  . VAL D 1 153 ? 21.267  20.955  50.134 1.00 25.80  ? 355 VAL D CA  1 
ATOM   10529 C C   . VAL D 1 153 ? 22.499  21.581  50.757 1.00 27.14  ? 355 VAL D C   1 
ATOM   10530 O O   . VAL D 1 153 ? 23.262  22.248  50.047 1.00 27.03  ? 355 VAL D O   1 
ATOM   10531 C CB  . VAL D 1 153 ? 20.463  22.019  49.367 1.00 23.76  ? 355 VAL D CB  1 
ATOM   10532 C CG1 . VAL D 1 153 ? 19.332  21.364  48.601 1.00 25.56  ? 355 VAL D CG1 1 
ATOM   10533 C CG2 . VAL D 1 153 ? 19.927  23.059  50.323 1.00 22.59  ? 355 VAL D CG2 1 
ATOM   10534 N N   . LEU D 1 154 ? 22.717  21.408  52.061 1.00 26.71  ? 356 LEU D N   1 
ATOM   10535 C CA  . LEU D 1 154 ? 23.779  22.156  52.725 1.00 28.19  ? 356 LEU D CA  1 
ATOM   10536 C C   . LEU D 1 154 ? 25.146  21.498  52.592 1.00 30.61  ? 356 LEU D C   1 
ATOM   10537 O O   . LEU D 1 154 ? 26.137  22.068  53.059 1.00 32.76  ? 356 LEU D O   1 
ATOM   10538 C CB  . LEU D 1 154 ? 23.450  22.349  54.203 1.00 30.32  ? 356 LEU D CB  1 
ATOM   10539 C CG  . LEU D 1 154 ? 22.185  23.137  54.529 1.00 29.06  ? 356 LEU D CG  1 
ATOM   10540 C CD1 . LEU D 1 154 ? 21.982  23.217  56.030 1.00 28.71  ? 356 LEU D CD1 1 
ATOM   10541 C CD2 . LEU D 1 154 ? 22.243  24.514  53.913 1.00 28.15  ? 356 LEU D CD2 1 
ATOM   10542 N N   . GLY D 1 155 ? 25.230  20.326  51.974 1.00 27.97  ? 357 GLY D N   1 
ATOM   10543 C CA  . GLY D 1 155 ? 26.498  19.656  51.791 1.00 29.73  ? 357 GLY D CA  1 
ATOM   10544 C C   . GLY D 1 155 ? 27.156  19.881  50.449 1.00 29.04  ? 357 GLY D C   1 
ATOM   10545 O O   . GLY D 1 155 ? 28.138  19.201  50.134 1.00 27.87  ? 357 GLY D O   1 
ATOM   10546 N N   . SER D 1 156 ? 26.687  20.862  49.685 1.00 30.79  ? 358 SER D N   1 
ATOM   10547 C CA  . SER D 1 156 ? 27.252  21.120  48.362 1.00 28.11  ? 358 SER D CA  1 
ATOM   10548 C C   . SER D 1 156 ? 28.132  22.361  48.202 1.00 27.64  ? 358 SER D C   1 
ATOM   10549 O O   . SER D 1 156 ? 28.218  22.909  47.107 1.00 27.24  ? 358 SER D O   1 
ATOM   10550 C CB  . SER D 1 156 ? 26.141  21.143  47.319 1.00 24.16  ? 358 SER D CB  1 
ATOM   10551 O OG  . SER D 1 156 ? 25.592  19.852  47.169 1.00 26.15  ? 358 SER D OG  1 
ATOM   10552 N N   . ALA D 1 157 ? 28.742  22.820  49.290 1.00 29.72  ? 359 ALA D N   1 
ATOM   10553 C CA  . ALA D 1 157 ? 29.649  23.968  49.255 1.00 28.23  ? 359 ALA D CA  1 
ATOM   10554 C C   . ALA D 1 157 ? 29.060  25.208  48.606 1.00 28.32  ? 359 ALA D C   1 
ATOM   10555 O O   . ALA D 1 157 ? 29.716  25.853  47.803 1.00 27.98  ? 359 ALA D O   1 
ATOM   10556 C CB  . ALA D 1 157 ? 30.972  23.601  48.605 1.00 27.68  ? 359 ALA D CB  1 
ATOM   10557 N N   . HIS D 1 158 ? 27.817  25.524  48.935 1.00 28.37  ? 360 HIS D N   1 
ATOM   10558 C CA  . HIS D 1 158 ? 27.142  26.687  48.368 1.00 29.21  ? 360 HIS D CA  1 
ATOM   10559 C C   . HIS D 1 158 ? 27.446  28.050  48.987 1.00 31.24  ? 360 HIS D C   1 
ATOM   10560 O O   . HIS D 1 158 ? 27.936  28.163  50.104 1.00 32.02  ? 360 HIS D O   1 
ATOM   10561 C CB  . HIS D 1 158 ? 25.628  26.482  48.373 1.00 24.57  ? 360 HIS D CB  1 
ATOM   10562 C CG  . HIS D 1 158 ? 25.132  25.623  47.259 1.00 26.36  ? 360 HIS D CG  1 
ATOM   10563 N ND1 . HIS D 1 158 ? 25.413  25.887  45.938 1.00 26.48  ? 360 HIS D ND1 1 
ATOM   10564 C CD2 . HIS D 1 158 ? 24.359  24.515  47.265 1.00 27.62  ? 360 HIS D CD2 1 
ATOM   10565 C CE1 . HIS D 1 158 ? 24.844  24.971  45.178 1.00 27.41  ? 360 HIS D CE1 1 
ATOM   10566 N NE2 . HIS D 1 158 ? 24.198  24.127  45.959 1.00 28.15  ? 360 HIS D NE2 1 
ATOM   10567 N N   . GLU D 1 159 ? 27.129  29.080  48.209 1.00 34.60  ? 361 GLU D N   1 
ATOM   10568 C CA  . GLU D 1 159 ? 27.226  30.483  48.595 1.00 36.74  ? 361 GLU D CA  1 
ATOM   10569 C C   . GLU D 1 159 ? 25.995  30.849  49.437 1.00 36.40  ? 361 GLU D C   1 
ATOM   10570 O O   . GLU D 1 159 ? 25.026  30.097  49.498 1.00 36.44  ? 361 GLU D O   1 
ATOM   10571 C CB  . GLU D 1 159 ? 27.276  31.373  47.354 1.00 33.15  ? 361 GLU D CB  1 
ATOM   10572 C CG  . GLU D 1 159 ? 28.618  31.413  46.651 1.00 43.12  ? 361 GLU D CG  1 
ATOM   10573 C CD  . GLU D 1 159 ? 29.554  32.435  47.257 1.00 47.80  ? 361 GLU D CD  1 
ATOM   10574 O OE1 . GLU D 1 159 ? 30.397  32.986  46.523 1.00 49.82  ? 361 GLU D OE1 1 
ATOM   10575 O OE2 . GLU D 1 159 ? 29.442  32.695  48.467 1.00 49.67  ? 361 GLU D OE2 1 
ATOM   10576 N N   . GLY D 1 160 ? 26.010  32.017  50.062 1.00 43.32  ? 362 GLY D N   1 
ATOM   10577 C CA  . GLY D 1 160 ? 24.886  32.426  50.883 1.00 42.70  ? 362 GLY D CA  1 
ATOM   10578 C C   . GLY D 1 160 ? 25.037  32.168  52.367 1.00 42.41  ? 362 GLY D C   1 
ATOM   10579 O O   . GLY D 1 160 ? 24.104  32.368  53.139 1.00 42.35  ? 362 GLY D O   1 
ATOM   10580 N N   . CYS D 1 161 ? 26.221  31.716  52.764 1.00 44.31  ? 363 CYS D N   1 
ATOM   10581 C CA  . CYS D 1 161 ? 26.555  31.490  54.169 1.00 44.49  ? 363 CYS D CA  1 
ATOM   10582 C C   . CYS D 1 161 ? 26.825  32.828  54.852 1.00 42.04  ? 363 CYS D C   1 
ATOM   10583 O O   . CYS D 1 161 ? 27.096  33.825  54.182 1.00 41.52  ? 363 CYS D O   1 
ATOM   10584 C CB  . CYS D 1 161 ? 27.816  30.637  54.291 1.00 45.78  ? 363 CYS D CB  1 
ATOM   10585 S SG  . CYS D 1 161 ? 27.608  28.879  53.973 1.00 54.86  ? 363 CYS D SG  1 
ATOM   10586 N N   . LEU D 1 162 ? 26.791  32.849  56.182 1.00 45.70  ? 364 LEU D N   1 
ATOM   10587 C CA  . LEU D 1 162 ? 27.066  34.081  56.917 1.00 44.60  ? 364 LEU D CA  1 
ATOM   10588 C C   . LEU D 1 162 ? 28.469  34.538  56.548 1.00 44.26  ? 364 LEU D C   1 
ATOM   10589 O O   . LEU D 1 162 ? 29.405  33.746  56.538 1.00 44.31  ? 364 LEU D O   1 
ATOM   10590 C CB  . LEU D 1 162 ? 26.987  33.839  58.423 1.00 41.50  ? 364 LEU D CB  1 
ATOM   10591 C CG  . LEU D 1 162 ? 25.607  33.762  59.070 1.00 42.23  ? 364 LEU D CG  1 
ATOM   10592 C CD1 . LEU D 1 162 ? 24.582  33.158  58.131 1.00 41.68  ? 364 LEU D CD1 1 
ATOM   10593 C CD2 . LEU D 1 162 ? 25.676  32.988  60.372 1.00 40.97  ? 364 LEU D CD2 1 
ATOM   10594 N N   . PRO D 1 163 ? 28.617  35.832  56.261 1.00 45.71  ? 365 PRO D N   1 
ATOM   10595 C CA  . PRO D 1 163 ? 29.893  36.388  55.821 1.00 44.85  ? 365 PRO D CA  1 
ATOM   10596 C C   . PRO D 1 163 ? 30.948  36.315  56.892 1.00 44.11  ? 365 PRO D C   1 
ATOM   10597 O O   . PRO D 1 163 ? 30.627  36.378  58.070 1.00 44.24  ? 365 PRO D O   1 
ATOM   10598 C CB  . PRO D 1 163 ? 29.546  37.844  55.536 1.00 47.53  ? 365 PRO D CB  1 
ATOM   10599 C CG  . PRO D 1 163 ? 28.450  38.136  56.495 1.00 48.02  ? 365 PRO D CG  1 
ATOM   10600 C CD  . PRO D 1 163 ? 27.628  36.885  56.537 1.00 47.21  ? 365 PRO D CD  1 
ATOM   10601 N N   . PRO D 1 164 ? 32.209  36.188  56.484 1.00 44.35  ? 366 PRO D N   1 
ATOM   10602 C CA  . PRO D 1 164 ? 33.293  36.125  57.474 1.00 43.90  ? 366 PRO D CA  1 
ATOM   10603 C C   . PRO D 1 164 ? 33.409  37.367  58.336 1.00 44.30  ? 366 PRO D C   1 
ATOM   10604 O O   . PRO D 1 164 ? 34.081  37.325  59.374 1.00 44.46  ? 366 PRO D O   1 
ATOM   10605 C CB  . PRO D 1 164 ? 34.540  35.935  56.603 1.00 41.32  ? 366 PRO D CB  1 
ATOM   10606 C CG  . PRO D 1 164 ? 34.183  36.578  55.313 1.00 41.40  ? 366 PRO D CG  1 
ATOM   10607 C CD  . PRO D 1 164 ? 32.725  36.280  55.108 1.00 41.62  ? 366 PRO D CD  1 
ATOM   10608 N N   . PHE D 1 165 ? 32.794  38.471  57.939 1.00 49.79  ? 367 PHE D N   1 
ATOM   10609 C CA  . PHE D 1 165 ? 33.042  39.705  58.670 1.00 50.73  ? 367 PHE D CA  1 
ATOM   10610 C C   . PHE D 1 165 ? 31.779  40.139  59.399 1.00 51.71  ? 367 PHE D C   1 
ATOM   10611 O O   . PHE D 1 165 ? 30.757  40.404  58.750 1.00 51.54  ? 367 PHE D O   1 
ATOM   10612 C CB  . PHE D 1 165 ? 33.510  40.794  57.710 1.00 50.71  ? 367 PHE D CB  1 
ATOM   10613 C CG  . PHE D 1 165 ? 33.973  42.048  58.388 1.00 52.03  ? 367 PHE D CG  1 
ATOM   10614 C CD1 . PHE D 1 165 ? 35.219  42.098  58.986 1.00 52.75  ? 367 PHE D CD1 1 
ATOM   10615 C CD2 . PHE D 1 165 ? 33.185  43.184  58.398 1.00 52.13  ? 367 PHE D CD2 1 
ATOM   10616 C CE1 . PHE D 1 165 ? 35.664  43.247  59.603 1.00 53.37  ? 367 PHE D CE1 1 
ATOM   10617 C CE2 . PHE D 1 165 ? 33.629  44.342  59.007 1.00 52.84  ? 367 PHE D CE2 1 
ATOM   10618 C CZ  . PHE D 1 165 ? 34.867  44.371  59.615 1.00 53.51  ? 367 PHE D CZ  1 
ATOM   10619 N N   . PRO D 1 166 ? 31.817  40.219  60.734 1.00 49.51  ? 368 PRO D N   1 
ATOM   10620 C CA  . PRO D 1 166 ? 30.577  40.398  61.506 1.00 49.80  ? 368 PRO D CA  1 
ATOM   10621 C C   . PRO D 1 166 ? 29.786  41.653  61.176 1.00 50.62  ? 368 PRO D C   1 
ATOM   10622 O O   . PRO D 1 166 ? 28.599  41.710  61.517 1.00 51.81  ? 368 PRO D O   1 
ATOM   10623 C CB  . PRO D 1 166 ? 31.076  40.430  62.954 1.00 49.33  ? 368 PRO D CB  1 
ATOM   10624 C CG  . PRO D 1 166 ? 32.321  39.628  62.926 1.00 49.71  ? 368 PRO D CG  1 
ATOM   10625 C CD  . PRO D 1 166 ? 32.964  39.910  61.603 1.00 50.02  ? 368 PRO D CD  1 
ATOM   10626 N N   . ALA D 1 167 ? 30.384  42.660  60.546 1.00 51.20  ? 369 ALA D N   1 
ATOM   10627 C CA  . ALA D 1 167 ? 29.648  43.878  60.239 1.00 51.38  ? 369 ALA D CA  1 
ATOM   10628 C C   . ALA D 1 167 ? 28.977  43.847  58.874 1.00 52.41  ? 369 ALA D C   1 
ATOM   10629 O O   . ALA D 1 167 ? 28.300  44.816  58.516 1.00 52.90  ? 369 ALA D O   1 
ATOM   10630 C CB  . ALA D 1 167 ? 30.567  45.097  60.325 1.00 51.26  ? 369 ALA D CB  1 
ATOM   10631 N N   . ASP D 1 168 ? 29.140  42.770  58.113 1.00 49.20  ? 370 ASP D N   1 
ATOM   10632 C CA  . ASP D 1 168 ? 28.491  42.656  56.817 1.00 51.41  ? 370 ASP D CA  1 
ATOM   10633 C C   . ASP D 1 168 ? 27.056  42.167  56.970 1.00 49.40  ? 370 ASP D C   1 
ATOM   10634 O O   . ASP D 1 168 ? 26.734  41.381  57.866 1.00 49.69  ? 370 ASP D O   1 
ATOM   10635 C CB  . ASP D 1 168 ? 29.261  41.700  55.906 1.00 49.66  ? 370 ASP D CB  1 
ATOM   10636 C CG  . ASP D 1 168 ? 30.592  42.261  55.461 1.00 55.89  ? 370 ASP D CG  1 
ATOM   10637 O OD1 . ASP D 1 168 ? 30.805  43.482  55.606 1.00 58.45  ? 370 ASP D OD1 1 
ATOM   10638 O OD2 . ASP D 1 168 ? 31.426  41.479  54.958 1.00 58.84  ? 370 ASP D OD2 1 
ATOM   10639 N N   . VAL D 1 169 ? 26.190  42.646  56.084 1.00 46.58  ? 371 VAL D N   1 
ATOM   10640 C CA  . VAL D 1 169 ? 24.811  42.187  55.989 1.00 43.52  ? 371 VAL D CA  1 
ATOM   10641 C C   . VAL D 1 169 ? 24.691  41.350  54.724 1.00 43.06  ? 371 VAL D C   1 
ATOM   10642 O O   . VAL D 1 169 ? 25.149  41.764  53.653 1.00 42.94  ? 371 VAL D O   1 
ATOM   10643 C CB  . VAL D 1 169 ? 23.822  43.365  55.983 1.00 40.16  ? 371 VAL D CB  1 
ATOM   10644 C CG1 . VAL D 1 169 ? 22.395  42.871  55.793 1.00 38.86  ? 371 VAL D CG1 1 
ATOM   10645 C CG2 . VAL D 1 169 ? 23.949  44.166  57.266 1.00 39.22  ? 371 VAL D CG2 1 
ATOM   10646 N N   . PHE D 1 170 ? 24.080  40.176  54.848 1.00 39.87  ? 372 PHE D N   1 
ATOM   10647 C CA  . PHE D 1 170 ? 24.037  39.200  53.773 1.00 40.00  ? 372 PHE D CA  1 
ATOM   10648 C C   . PHE D 1 170 ? 22.594  38.893  53.399 1.00 40.64  ? 372 PHE D C   1 
ATOM   10649 O O   . PHE D 1 170 ? 21.661  39.131  54.171 1.00 40.54  ? 372 PHE D O   1 
ATOM   10650 C CB  . PHE D 1 170 ? 24.760  37.905  54.171 1.00 38.82  ? 372 PHE D CB  1 
ATOM   10651 C CG  . PHE D 1 170 ? 24.113  37.173  55.310 1.00 39.00  ? 372 PHE D CG  1 
ATOM   10652 C CD1 . PHE D 1 170 ? 23.211  36.154  55.069 1.00 38.53  ? 372 PHE D CD1 1 
ATOM   10653 C CD2 . PHE D 1 170 ? 24.384  37.524  56.617 1.00 39.27  ? 372 PHE D CD2 1 
ATOM   10654 C CE1 . PHE D 1 170 ? 22.609  35.482  56.112 1.00 38.41  ? 372 PHE D CE1 1 
ATOM   10655 C CE2 . PHE D 1 170 ? 23.787  36.857  57.662 1.00 38.71  ? 372 PHE D CE2 1 
ATOM   10656 C CZ  . PHE D 1 170 ? 22.896  35.835  57.411 1.00 38.04  ? 372 PHE D CZ  1 
ATOM   10657 N N   . MET D 1 171 ? 22.427  38.355  52.198 1.00 35.86  ? 373 MET D N   1 
ATOM   10658 C CA  . MET D 1 171 ? 21.127  37.984  51.665 1.00 35.72  ? 373 MET D CA  1 
ATOM   10659 C C   . MET D 1 171 ? 20.894  36.492  51.864 1.00 34.03  ? 373 MET D C   1 
ATOM   10660 O O   . MET D 1 171 ? 21.711  35.666  51.449 1.00 35.24  ? 373 MET D O   1 
ATOM   10661 C CB  . MET D 1 171 ? 21.043  38.345  50.181 1.00 29.58  ? 373 MET D CB  1 
ATOM   10662 C CG  . MET D 1 171 ? 19.731  38.010  49.506 1.00 34.28  ? 373 MET D CG  1 
ATOM   10663 S SD  . MET D 1 171 ? 19.669  38.676  47.835 1.00 39.33  ? 373 MET D SD  1 
ATOM   10664 C CE  . MET D 1 171 ? 18.140  37.960  47.244 1.00 41.24  ? 373 MET D CE  1 
ATOM   10665 N N   . ILE D 1 172 ? 19.786  36.156  52.510 1.00 35.04  ? 374 ILE D N   1 
ATOM   10666 C CA  . ILE D 1 172 ? 19.445  34.755  52.770 1.00 33.71  ? 374 ILE D CA  1 
ATOM   10667 C C   . ILE D 1 172 ? 19.141  34.064  51.444 1.00 33.04  ? 374 ILE D C   1 
ATOM   10668 O O   . ILE D 1 172 ? 18.308  34.564  50.673 1.00 33.62  ? 374 ILE D O   1 
ATOM   10669 C CB  . ILE D 1 172 ? 18.258  34.659  53.718 1.00 34.77  ? 374 ILE D CB  1 
ATOM   10670 C CG1 . ILE D 1 172 ? 18.648  35.128  55.113 1.00 35.85  ? 374 ILE D CG1 1 
ATOM   10671 C CG2 . ILE D 1 172 ? 17.717  33.243  53.765 1.00 33.99  ? 374 ILE D CG2 1 
ATOM   10672 C CD1 . ILE D 1 172 ? 17.481  35.198  56.029 1.00 40.00  ? 374 ILE D CD1 1 
ATOM   10673 N N   . PRO D 1 173 ? 19.767  32.929  51.153 1.00 29.30  ? 375 PRO D N   1 
ATOM   10674 C CA  . PRO D 1 173 ? 19.567  32.279  49.858 1.00 29.43  ? 375 PRO D CA  1 
ATOM   10675 C C   . PRO D 1 173 ? 18.196  31.628  49.747 1.00 29.75  ? 375 PRO D C   1 
ATOM   10676 O O   . PRO D 1 173 ? 17.470  31.455  50.726 1.00 30.46  ? 375 PRO D O   1 
ATOM   10677 C CB  . PRO D 1 173 ? 20.682  31.230  49.818 1.00 31.26  ? 375 PRO D CB  1 
ATOM   10678 C CG  . PRO D 1 173 ? 20.941  30.919  51.242 1.00 30.86  ? 375 PRO D CG  1 
ATOM   10679 C CD  . PRO D 1 173 ? 20.724  32.195  51.998 1.00 31.24  ? 375 PRO D CD  1 
ATOM   10680 N N   . GLN D 1 174 ? 17.843  31.289  48.512 1.00 24.95  ? 376 GLN D N   1 
ATOM   10681 C CA  . GLN D 1 174 ? 16.579  30.622  48.241 1.00 24.25  ? 376 GLN D CA  1 
ATOM   10682 C C   . GLN D 1 174 ? 16.769  29.111  48.249 1.00 24.50  ? 376 GLN D C   1 
ATOM   10683 O O   . GLN D 1 174 ? 17.774  28.596  47.757 1.00 24.78  ? 376 GLN D O   1 
ATOM   10684 C CB  . GLN D 1 174 ? 16.018  31.071  46.895 1.00 22.03  ? 376 GLN D CB  1 
ATOM   10685 C CG  . GLN D 1 174 ? 14.612  30.591  46.639 1.00 22.51  ? 376 GLN D CG  1 
ATOM   10686 C CD  . GLN D 1 174 ? 14.046  31.113  45.343 1.00 24.89  ? 376 GLN D CD  1 
ATOM   10687 O OE1 . GLN D 1 174 ? 14.700  31.862  44.620 1.00 26.26  ? 376 GLN D OE1 1 
ATOM   10688 N NE2 . GLN D 1 174 ? 12.814  30.732  45.047 1.00 25.53  ? 376 GLN D NE2 1 
ATOM   10689 N N   . TYR D 1 175 ? 15.798  28.400  48.813 1.00 22.00  ? 377 TYR D N   1 
ATOM   10690 C CA  . TYR D 1 175 ? 15.887  26.952  48.923 1.00 21.24  ? 377 TYR D CA  1 
ATOM   10691 C C   . TYR D 1 175 ? 15.258  26.279  47.712 1.00 22.07  ? 377 TYR D C   1 
ATOM   10692 O O   . TYR D 1 175 ? 14.183  26.670  47.251 1.00 22.46  ? 377 TYR D O   1 
ATOM   10693 C CB  . TYR D 1 175 ? 15.206  26.455  50.198 1.00 21.76  ? 377 TYR D CB  1 
ATOM   10694 C CG  . TYR D 1 175 ? 15.235  24.950  50.354 1.00 22.02  ? 377 TYR D CG  1 
ATOM   10695 C CD1 . TYR D 1 175 ? 16.380  24.300  50.787 1.00 21.70  ? 377 TYR D CD1 1 
ATOM   10696 C CD2 . TYR D 1 175 ? 14.115  24.179  50.070 1.00 21.99  ? 377 TYR D CD2 1 
ATOM   10697 C CE1 . TYR D 1 175 ? 16.410  22.931  50.933 1.00 21.72  ? 377 TYR D CE1 1 
ATOM   10698 C CE2 . TYR D 1 175 ? 14.137  22.811  50.210 1.00 21.95  ? 377 TYR D CE2 1 
ATOM   10699 C CZ  . TYR D 1 175 ? 15.286  22.192  50.644 1.00 22.80  ? 377 TYR D CZ  1 
ATOM   10700 O OH  . TYR D 1 175 ? 15.312  20.827  50.787 1.00 22.69  ? 377 TYR D OH  1 
ATOM   10701 N N   . GLY D 1 176 ? 15.940  25.261  47.206 1.00 19.62  ? 378 GLY D N   1 
ATOM   10702 C CA  . GLY D 1 176 ? 15.453  24.475  46.090 1.00 19.79  ? 378 GLY D CA  1 
ATOM   10703 C C   . GLY D 1 176 ? 15.997  23.073  46.210 1.00 19.97  ? 378 GLY D C   1 
ATOM   10704 O O   . GLY D 1 176 ? 16.913  22.803  46.988 1.00 19.72  ? 378 GLY D O   1 
ATOM   10705 N N   . TYR D 1 177 ? 15.407  22.169  45.437 1.00 15.38  ? 379 TYR D N   1 
ATOM   10706 C CA  . TYR D 1 177 ? 15.829  20.781  45.486 1.00 15.76  ? 379 TYR D CA  1 
ATOM   10707 C C   . TYR D 1 177 ? 15.603  20.132  44.134 1.00 16.46  ? 379 TYR D C   1 
ATOM   10708 O O   . TYR D 1 177 ? 14.627  20.418  43.438 1.00 16.31  ? 379 TYR D O   1 
ATOM   10709 C CB  . TYR D 1 177 ? 15.097  20.009  46.587 1.00 13.44  ? 379 TYR D CB  1 
ATOM   10710 C CG  . TYR D 1 177 ? 13.589  19.974  46.451 1.00 14.16  ? 379 TYR D CG  1 
ATOM   10711 C CD1 . TYR D 1 177 ? 12.958  18.982  45.713 1.00 14.03  ? 379 TYR D CD1 1 
ATOM   10712 C CD2 . TYR D 1 177 ? 12.800  20.918  47.087 1.00 14.20  ? 379 TYR D CD2 1 
ATOM   10713 C CE1 . TYR D 1 177 ? 11.590  18.947  45.598 1.00 14.91  ? 379 TYR D CE1 1 
ATOM   10714 C CE2 . TYR D 1 177 ? 11.435  20.889  46.980 1.00 14.98  ? 379 TYR D CE2 1 
ATOM   10715 C CZ  . TYR D 1 177 ? 10.833  19.903  46.235 1.00 15.99  ? 379 TYR D CZ  1 
ATOM   10716 O OH  . TYR D 1 177 ? 9.463   19.877  46.133 1.00 17.14  ? 379 TYR D OH  1 
ATOM   10717 N N   . LEU D 1 178 ? 16.520  19.240  43.780 1.00 13.40  ? 380 LEU D N   1 
ATOM   10718 C CA  . LEU D 1 178 ? 16.445  18.463  42.556 1.00 14.42  ? 380 LEU D CA  1 
ATOM   10719 C C   . LEU D 1 178 ? 16.002  17.044  42.868 1.00 16.76  ? 380 LEU D C   1 
ATOM   10720 O O   . LEU D 1 178 ? 16.381  16.468  43.890 1.00 17.96  ? 380 LEU D O   1 
ATOM   10721 C CB  . LEU D 1 178 ? 17.794  18.423  41.844 1.00 16.28  ? 380 LEU D CB  1 
ATOM   10722 C CG  . LEU D 1 178 ? 18.306  19.761  41.341 1.00 16.66  ? 380 LEU D CG  1 
ATOM   10723 C CD1 . LEU D 1 178 ? 19.699  19.592  40.801 1.00 16.26  ? 380 LEU D CD1 1 
ATOM   10724 C CD2 . LEU D 1 178 ? 17.374  20.280  40.278 1.00 16.11  ? 380 LEU D CD2 1 
ATOM   10725 N N   . THR D 1 179 ? 15.203  16.482  41.971 1.00 12.77  ? 381 THR D N   1 
ATOM   10726 C CA  . THR D 1 179 ? 14.752  15.105  42.073 1.00 15.30  ? 381 THR D CA  1 
ATOM   10727 C C   . THR D 1 179 ? 15.092  14.386  40.774 1.00 15.52  ? 381 THR D C   1 
ATOM   10728 O O   . THR D 1 179 ? 15.777  14.928  39.902 1.00 15.42  ? 381 THR D O   1 
ATOM   10729 C CB  . THR D 1 179 ? 13.255  15.037  42.398 1.00 13.80  ? 381 THR D CB  1 
ATOM   10730 O OG1 . THR D 1 179 ? 12.876  13.677  42.628 1.00 15.51  ? 381 THR D OG1 1 
ATOM   10731 C CG2 . THR D 1 179 ? 12.429  15.614  41.274 1.00 15.71  ? 381 THR D CG2 1 
ATOM   10732 N N   . LEU D 1 180 ? 14.626  13.147  40.656 1.00 14.60  ? 382 LEU D N   1 
ATOM   10733 C CA  . LEU D 1 180 ? 14.996  12.304  39.527 1.00 15.10  ? 382 LEU D CA  1 
ATOM   10734 C C   . LEU D 1 180 ? 14.484  12.885  38.221 1.00 16.69  ? 382 LEU D C   1 
ATOM   10735 O O   . LEU D 1 180 ? 13.425  13.517  38.182 1.00 17.01  ? 382 LEU D O   1 
ATOM   10736 C CB  . LEU D 1 180 ? 14.442  10.898  39.718 1.00 15.28  ? 382 LEU D CB  1 
ATOM   10737 C CG  . LEU D 1 180 ? 14.953  10.130  40.923 1.00 14.74  ? 382 LEU D CG  1 
ATOM   10738 C CD1 . LEU D 1 180 ? 14.270  8.787   40.989 1.00 14.40  ? 382 LEU D CD1 1 
ATOM   10739 C CD2 . LEU D 1 180 ? 16.449  9.982   40.843 1.00 14.06  ? 382 LEU D CD2 1 
ATOM   10740 N N   . ASN D 1 181 ? 15.226  12.647  37.146 1.00 16.28  ? 383 ASN D N   1 
ATOM   10741 C CA  . ASN D 1 181 ? 14.831  13.074  35.815 1.00 18.35  ? 383 ASN D CA  1 
ATOM   10742 C C   . ASN D 1 181 ? 15.313  12.062  34.792 1.00 21.00  ? 383 ASN D C   1 
ATOM   10743 O O   . ASN D 1 181 ? 16.248  11.301  35.058 1.00 21.08  ? 383 ASN D O   1 
ATOM   10744 C CB  . ASN D 1 181 ? 15.413  14.445  35.468 1.00 20.89  ? 383 ASN D CB  1 
ATOM   10745 C CG  . ASN D 1 181 ? 16.923  14.436  35.415 1.00 21.22  ? 383 ASN D CG  1 
ATOM   10746 O OD1 . ASN D 1 181 ? 17.573  13.591  36.022 1.00 22.21  ? 383 ASN D OD1 1 
ATOM   10747 N ND2 . ASN D 1 181 ? 17.488  15.338  34.636 1.00 20.96  ? 383 ASN D ND2 1 
ATOM   10748 N N   . ASP D 1 182 ? 14.668  12.049  33.633 1.00 22.11  ? 384 ASP D N   1 
ATOM   10749 C CA  . ASP D 1 182 ? 15.254  11.520  32.411 1.00 24.72  ? 384 ASP D CA  1 
ATOM   10750 C C   . ASP D 1 182 ? 15.262  12.652  31.397 1.00 23.82  ? 384 ASP D C   1 
ATOM   10751 O O   . ASP D 1 182 ? 14.208  13.021  30.871 1.00 24.01  ? 384 ASP D O   1 
ATOM   10752 C CB  . ASP D 1 182 ? 14.466  10.322  31.887 1.00 26.59  ? 384 ASP D CB  1 
ATOM   10753 C CG  . ASP D 1 182 ? 15.084  9.722   30.642 1.00 30.91  ? 384 ASP D CG  1 
ATOM   10754 O OD1 . ASP D 1 182 ? 16.195  9.162   30.744 1.00 33.82  ? 384 ASP D OD1 1 
ATOM   10755 O OD2 . ASP D 1 182 ? 14.464  9.812   29.562 1.00 33.22  ? 384 ASP D OD2 1 
ATOM   10756 N N   . GLY D 1 183 ? 16.443  13.180  31.103 1.00 21.82  ? 385 GLY D N   1 
ATOM   10757 C CA  . GLY D 1 183 ? 16.487  14.431  30.365 1.00 20.88  ? 385 GLY D CA  1 
ATOM   10758 C C   . GLY D 1 183 ? 15.877  15.532  31.209 1.00 20.48  ? 385 GLY D C   1 
ATOM   10759 O O   . GLY D 1 183 ? 16.105  15.611  32.419 1.00 20.76  ? 385 GLY D O   1 
ATOM   10760 N N   . SER D 1 184 ? 15.080  16.393  30.580 1.00 21.82  ? 386 SER D N   1 
ATOM   10761 C CA  . SER D 1 184 ? 14.409  17.474  31.287 1.00 20.39  ? 386 SER D CA  1 
ATOM   10762 C C   . SER D 1 184 ? 13.068  17.049  31.866 1.00 19.81  ? 386 SER D C   1 
ATOM   10763 O O   . SER D 1 184 ? 12.453  17.819  32.605 1.00 19.98  ? 386 SER D O   1 
ATOM   10764 C CB  . SER D 1 184 ? 14.215  18.675  30.363 1.00 24.51  ? 386 SER D CB  1 
ATOM   10765 O OG  . SER D 1 184 ? 13.345  18.358  29.293 1.00 26.20  ? 386 SER D OG  1 
ATOM   10766 N N   . GLN D 1 185 ? 12.601  15.851  31.544 1.00 19.37  ? 387 GLN D N   1 
ATOM   10767 C CA  . GLN D 1 185 ? 11.334  15.350  32.047 1.00 18.81  ? 387 GLN D CA  1 
ATOM   10768 C C   . GLN D 1 185 ? 11.500  14.743  33.433 1.00 18.50  ? 387 GLN D C   1 
ATOM   10769 O O   . GLN D 1 185 ? 12.590  14.709  34.004 1.00 18.61  ? 387 GLN D O   1 
ATOM   10770 C CB  . GLN D 1 185 ? 10.740  14.327  31.080 1.00 18.14  ? 387 GLN D CB  1 
ATOM   10771 C CG  . GLN D 1 185 ? 10.209  14.942  29.805 1.00 19.56  ? 387 GLN D CG  1 
ATOM   10772 C CD  . GLN D 1 185 ? 9.651   13.913  28.862 1.00 21.32  ? 387 GLN D CD  1 
ATOM   10773 O OE1 . GLN D 1 185 ? 10.085  12.767  28.856 1.00 22.70  ? 387 GLN D OE1 1 
ATOM   10774 N NE2 . GLN D 1 185 ? 8.660   14.307  28.077 1.00 21.01  ? 387 GLN D NE2 1 
ATOM   10775 N N   . ALA D 1 186 ? 10.389  14.261  33.974 1.00 19.06  ? 388 ALA D N   1 
ATOM   10776 C CA  . ALA D 1 186 ? 10.346  13.688  35.308 1.00 18.15  ? 388 ALA D CA  1 
ATOM   10777 C C   . ALA D 1 186 ? 9.765   12.287  35.247 1.00 18.10  ? 388 ALA D C   1 
ATOM   10778 O O   . ALA D 1 186 ? 8.721   12.065  34.628 1.00 17.90  ? 388 ALA D O   1 
ATOM   10779 C CB  . ALA D 1 186 ? 9.506   14.541  36.247 1.00 16.03  ? 388 ALA D CB  1 
ATOM   10780 N N   . VAL D 1 187 ? 10.444  11.349  35.881 1.00 17.18  ? 389 VAL D N   1 
ATOM   10781 C CA  . VAL D 1 187 ? 9.914   10.008  36.042 1.00 17.95  ? 389 VAL D CA  1 
ATOM   10782 C C   . VAL D 1 187 ? 8.931   10.008  37.205 1.00 17.55  ? 389 VAL D C   1 
ATOM   10783 O O   . VAL D 1 187 ? 9.006   10.835  38.115 1.00 17.52  ? 389 VAL D O   1 
ATOM   10784 C CB  . VAL D 1 187 ? 11.036  8.978   36.251 1.00 17.56  ? 389 VAL D CB  1 
ATOM   10785 C CG1 . VAL D 1 187 ? 11.918  8.917   35.026 1.00 20.42  ? 389 VAL D CG1 1 
ATOM   10786 C CG2 . VAL D 1 187 ? 11.851  9.326   37.477 1.00 17.28  ? 389 VAL D CG2 1 
ATOM   10787 N N   . GLY D 1 188 ? 7.991   9.069   37.172 1.00 18.45  ? 390 GLY D N   1 
ATOM   10788 C CA  . GLY D 1 188 ? 6.949   8.992   38.178 1.00 17.71  ? 390 GLY D CA  1 
ATOM   10789 C C   . GLY D 1 188 ? 7.452   8.775   39.589 1.00 17.69  ? 390 GLY D C   1 
ATOM   10790 O O   . GLY D 1 188 ? 6.717   8.986   40.557 1.00 17.72  ? 390 GLY D O   1 
ATOM   10791 N N   . ARG D 1 189 ? 8.705   8.347   39.719 1.00 18.16  ? 391 ARG D N   1 
ATOM   10792 C CA  . ARG D 1 189 ? 9.334   8.180   41.021 1.00 17.17  ? 391 ARG D CA  1 
ATOM   10793 C C   . ARG D 1 189 ? 9.842   9.497   41.604 1.00 15.67  ? 391 ARG D C   1 
ATOM   10794 O O   . ARG D 1 189 ? 10.157  9.550   42.797 1.00 16.35  ? 391 ARG D O   1 
ATOM   10795 C CB  . ARG D 1 189 ? 10.473  7.157   40.910 1.00 14.20  ? 391 ARG D CB  1 
ATOM   10796 C CG  . ARG D 1 189 ? 11.148  6.819   42.221 1.00 17.98  ? 391 ARG D CG  1 
ATOM   10797 C CD  . ARG D 1 189 ? 12.140  5.676   42.123 1.00 21.26  ? 391 ARG D CD  1 
ATOM   10798 N NE  . ARG D 1 189 ? 11.514  4.386   41.861 1.00 25.30  ? 391 ARG D NE  1 
ATOM   10799 C CZ  . ARG D 1 189 ? 11.633  3.712   40.725 1.00 27.40  ? 391 ARG D CZ  1 
ATOM   10800 N NH1 . ARG D 1 189 ? 12.370  4.198   39.740 1.00 27.94  ? 391 ARG D NH1 1 
ATOM   10801 N NH2 . ARG D 1 189 ? 11.029  2.543   40.581 1.00 29.01  ? 391 ARG D NH2 1 
ATOM   10802 N N   . SER D 1 190 ? 9.908   10.561  40.808 1.00 14.83  ? 392 SER D N   1 
ATOM   10803 C CA  . SER D 1 190 ? 10.257  11.874  41.330 1.00 13.60  ? 392 SER D CA  1 
ATOM   10804 C C   . SER D 1 190 ? 9.303   12.290  42.444 1.00 13.60  ? 392 SER D C   1 
ATOM   10805 O O   . SER D 1 190 ? 8.097   12.043  42.386 1.00 13.05  ? 392 SER D O   1 
ATOM   10806 C CB  . SER D 1 190 ? 10.227  12.919  40.218 1.00 14.17  ? 392 SER D CB  1 
ATOM   10807 O OG  . SER D 1 190 ? 11.225  12.671  39.249 1.00 15.18  ? 392 SER D OG  1 
ATOM   10808 N N   . SER D 1 191 ? 9.858   12.933  43.466 1.00 14.22  ? 393 SER D N   1 
ATOM   10809 C CA  . SER D 1 191 ? 9.103   13.367  44.630 1.00 12.71  ? 393 SER D CA  1 
ATOM   10810 C C   . SER D 1 191 ? 8.937   14.877  44.618 1.00 12.08  ? 393 SER D C   1 
ATOM   10811 O O   . SER D 1 191 ? 9.835   15.606  44.188 1.00 12.50  ? 393 SER D O   1 
ATOM   10812 C CB  . SER D 1 191 ? 9.792   12.938  45.925 1.00 10.37  ? 393 SER D CB  1 
ATOM   10813 O OG  . SER D 1 191 ? 9.814   11.531  46.049 1.00 14.26  ? 393 SER D OG  1 
ATOM   10814 N N   . PHE D 1 192 ? 7.786   15.340  45.092 1.00 12.98  ? 394 PHE D N   1 
ATOM   10815 C CA  . PHE D 1 192 ? 7.516   16.758  45.264 1.00 11.93  ? 394 PHE D CA  1 
ATOM   10816 C C   . PHE D 1 192 ? 7.208   17.042  46.724 1.00 13.19  ? 394 PHE D C   1 
ATOM   10817 O O   . PHE D 1 192 ? 6.179   16.607  47.246 1.00 13.22  ? 394 PHE D O   1 
ATOM   10818 C CB  . PHE D 1 192 ? 6.355   17.214  44.384 1.00 14.71  ? 394 PHE D CB  1 
ATOM   10819 C CG  . PHE D 1 192 ? 5.911   18.621  44.654 1.00 14.16  ? 394 PHE D CG  1 
ATOM   10820 C CD1 . PHE D 1 192 ? 6.662   19.693  44.219 1.00 14.08  ? 394 PHE D CD1 1 
ATOM   10821 C CD2 . PHE D 1 192 ? 4.730   18.870  45.329 1.00 14.50  ? 394 PHE D CD2 1 
ATOM   10822 C CE1 . PHE D 1 192 ? 6.254   20.984  44.466 1.00 13.63  ? 394 PHE D CE1 1 
ATOM   10823 C CE2 . PHE D 1 192 ? 4.319   20.160  45.574 1.00 13.91  ? 394 PHE D CE2 1 
ATOM   10824 C CZ  . PHE D 1 192 ? 5.080   21.215  45.144 1.00 13.38  ? 394 PHE D CZ  1 
ATOM   10825 N N   . TYR D 1 193 ? 8.098   17.778  47.380 1.00 13.05  ? 395 TYR D N   1 
ATOM   10826 C CA  . TYR D 1 193 ? 7.954   18.114  48.787 1.00 13.79  ? 395 TYR D CA  1 
ATOM   10827 C C   . TYR D 1 193 ? 7.384   19.515  48.914 1.00 15.44  ? 395 TYR D C   1 
ATOM   10828 O O   . TYR D 1 193 ? 7.849   20.442  48.244 1.00 15.54  ? 395 TYR D O   1 
ATOM   10829 C CB  . TYR D 1 193 ? 9.291   18.021  49.517 1.00 11.97  ? 395 TYR D CB  1 
ATOM   10830 C CG  . TYR D 1 193 ? 9.855   16.627  49.568 1.00 13.17  ? 395 TYR D CG  1 
ATOM   10831 C CD1 . TYR D 1 193 ? 9.501   15.756  50.582 1.00 14.18  ? 395 TYR D CD1 1 
ATOM   10832 C CD2 . TYR D 1 193 ? 10.741  16.182  48.602 1.00 14.33  ? 395 TYR D CD2 1 
ATOM   10833 C CE1 . TYR D 1 193 ? 10.015  14.484  50.635 1.00 16.01  ? 395 TYR D CE1 1 
ATOM   10834 C CE2 . TYR D 1 193 ? 11.257  14.909  48.646 1.00 16.74  ? 395 TYR D CE2 1 
ATOM   10835 C CZ  . TYR D 1 193 ? 10.891  14.064  49.665 1.00 17.17  ? 395 TYR D CZ  1 
ATOM   10836 O OH  . TYR D 1 193 ? 11.402  12.791  49.715 1.00 18.76  ? 395 TYR D OH  1 
ATOM   10837 N N   . CYS D 1 194 ? 6.377   19.663  49.766 1.00 19.45  ? 396 CYS D N   1 
ATOM   10838 C CA  . CYS D 1 194 ? 5.779   20.955  50.063 1.00 20.65  ? 396 CYS D CA  1 
ATOM   10839 C C   . CYS D 1 194 ? 6.274   21.415  51.428 1.00 20.03  ? 396 CYS D C   1 
ATOM   10840 O O   . CYS D 1 194 ? 5.983   20.775  52.443 1.00 20.67  ? 396 CYS D O   1 
ATOM   10841 C CB  . CYS D 1 194 ? 4.253   20.866  50.043 1.00 21.02  ? 396 CYS D CB  1 
ATOM   10842 S SG  . CYS D 1 194 ? 3.410   22.425  50.357 1.00 29.22  ? 396 CYS D SG  1 
ATOM   10843 N N   . LEU D 1 195 ? 7.029   22.514  51.451 1.00 24.01  ? 397 LEU D N   1 
ATOM   10844 C CA  . LEU D 1 195 ? 7.544   23.025  52.714 1.00 24.33  ? 397 LEU D CA  1 
ATOM   10845 C C   . LEU D 1 195 ? 6.459   23.665  53.565 1.00 25.90  ? 397 LEU D C   1 
ATOM   10846 O O   . LEU D 1 195 ? 6.648   23.820  54.775 1.00 26.23  ? 397 LEU D O   1 
ATOM   10847 C CB  . LEU D 1 195 ? 8.669   24.032  52.466 1.00 24.70  ? 397 LEU D CB  1 
ATOM   10848 C CG  . LEU D 1 195 ? 10.072  23.463  52.240 1.00 22.81  ? 397 LEU D CG  1 
ATOM   10849 C CD1 . LEU D 1 195 ? 10.157  22.674  50.944 1.00 20.74  ? 397 LEU D CD1 1 
ATOM   10850 C CD2 . LEU D 1 195 ? 11.104  24.571  52.257 1.00 22.47  ? 397 LEU D CD2 1 
ATOM   10851 N N   . GLU D 1 196 ? 5.331   24.037  52.966 1.00 27.64  ? 398 GLU D N   1 
ATOM   10852 C CA  . GLU D 1 196 ? 4.214   24.545  53.744 1.00 29.10  ? 398 GLU D CA  1 
ATOM   10853 C C   . GLU D 1 196 ? 3.534   23.448  54.543 1.00 28.72  ? 398 GLU D C   1 
ATOM   10854 O O   . GLU D 1 196 ? 2.692   23.750  55.396 1.00 29.19  ? 398 GLU D O   1 
ATOM   10855 C CB  . GLU D 1 196 ? 3.193   25.203  52.820 1.00 24.42  ? 398 GLU D CB  1 
ATOM   10856 C CG  . GLU D 1 196 ? 3.724   26.358  51.991 1.00 31.41  ? 398 GLU D CG  1 
ATOM   10857 C CD  . GLU D 1 196 ? 4.270   27.488  52.824 1.00 35.80  ? 398 GLU D CD  1 
ATOM   10858 O OE1 . GLU D 1 196 ? 3.703   27.768  53.899 1.00 39.44  ? 398 GLU D OE1 1 
ATOM   10859 O OE2 . GLU D 1 196 ? 5.259   28.109  52.390 1.00 36.71  ? 398 GLU D OE2 1 
ATOM   10860 N N   . TYR D 1 197 ? 3.875   22.190  54.280 1.00 29.25  ? 399 TYR D N   1 
ATOM   10861 C CA  . TYR D 1 197 ? 3.199   21.026  54.832 1.00 29.00  ? 399 TYR D CA  1 
ATOM   10862 C C   . TYR D 1 197 ? 3.879   20.500  56.093 1.00 27.67  ? 399 TYR D C   1 
ATOM   10863 O O   . TYR D 1 197 ? 3.506   19.438  56.594 1.00 27.26  ? 399 TYR D O   1 
ATOM   10864 C CB  . TYR D 1 197 ? 3.099   19.950  53.742 1.00 21.19  ? 399 TYR D CB  1 
ATOM   10865 C CG  . TYR D 1 197 ? 2.381   18.681  54.127 1.00 24.57  ? 399 TYR D CG  1 
ATOM   10866 C CD1 . TYR D 1 197 ? 1.009   18.672  54.326 1.00 25.31  ? 399 TYR D CD1 1 
ATOM   10867 C CD2 . TYR D 1 197 ? 3.066   17.481  54.240 1.00 25.66  ? 399 TYR D CD2 1 
ATOM   10868 C CE1 . TYR D 1 197 ? 0.347   17.512  54.665 1.00 27.14  ? 399 TYR D CE1 1 
ATOM   10869 C CE2 . TYR D 1 197 ? 2.410   16.317  54.576 1.00 27.81  ? 399 TYR D CE2 1 
ATOM   10870 C CZ  . TYR D 1 197 ? 1.053   16.339  54.786 1.00 29.03  ? 399 TYR D CZ  1 
ATOM   10871 O OH  . TYR D 1 197 ? 0.401   15.178  55.120 1.00 32.37  ? 399 TYR D OH  1 
ATOM   10872 N N   . PHE D 1 198 ? 4.868   21.196  56.592 1.00 30.11  ? 400 PHE D N   1 
ATOM   10873 C CA  . PHE D 1 198 ? 5.655   21.038  57.806 1.00 29.20  ? 400 PHE D CA  1 
ATOM   10874 C C   . PHE D 1 198 ? 5.197   22.014  58.884 1.00 28.98  ? 400 PHE D C   1 
ATOM   10875 O O   . PHE D 1 198 ? 5.066   23.214  58.628 1.00 30.51  ? 400 PHE D O   1 
ATOM   10876 C CB  . PHE D 1 198 ? 7.130   21.270  57.513 1.00 27.45  ? 400 PHE D CB  1 
ATOM   10877 C CG  . PHE D 1 198 ? 7.752   20.204  56.672 1.00 26.92  ? 400 PHE D CG  1 
ATOM   10878 C CD1 . PHE D 1 198 ? 8.350   19.108  57.262 1.00 26.64  ? 400 PHE D CD1 1 
ATOM   10879 C CD2 . PHE D 1 198 ? 7.712   20.280  55.294 1.00 26.62  ? 400 PHE D CD2 1 
ATOM   10880 C CE1 . PHE D 1 198 ? 8.923   18.125  56.494 1.00 27.69  ? 400 PHE D CE1 1 
ATOM   10881 C CE2 . PHE D 1 198 ? 8.274   19.296  54.522 1.00 27.47  ? 400 PHE D CE2 1 
ATOM   10882 C CZ  . PHE D 1 198 ? 8.881   18.216  55.123 1.00 28.43  ? 400 PHE D CZ  1 
ATOM   10883 N N   . PRO D 1 199 ? 4.945   21.530  60.098 1.00 33.12  ? 401 PRO D N   1 
ATOM   10884 C CA  . PRO D 1 199 ? 4.587   22.446  61.186 1.00 32.64  ? 401 PRO D CA  1 
ATOM   10885 C C   . PRO D 1 199 ? 5.732   23.398  61.494 1.00 31.96  ? 401 PRO D C   1 
ATOM   10886 O O   . PRO D 1 199 ? 6.869   22.979  61.718 1.00 31.73  ? 401 PRO D O   1 
ATOM   10887 C CB  . PRO D 1 199 ? 4.304   21.506  62.361 1.00 32.82  ? 401 PRO D CB  1 
ATOM   10888 C CG  . PRO D 1 199 ? 5.130   20.301  62.071 1.00 33.02  ? 401 PRO D CG  1 
ATOM   10889 C CD  . PRO D 1 199 ? 5.128   20.149  60.575 1.00 34.34  ? 401 PRO D CD  1 
ATOM   10890 N N   . SER D 1 200 ? 5.417   24.690  61.519 1.00 33.48  ? 402 SER D N   1 
ATOM   10891 C CA  . SER D 1 200 ? 6.429   25.724  61.672 1.00 32.79  ? 402 SER D CA  1 
ATOM   10892 C C   . SER D 1 200 ? 5.931   26.792  62.633 1.00 31.76  ? 402 SER D C   1 
ATOM   10893 O O   . SER D 1 200 ? 4.742   26.873  62.948 1.00 32.00  ? 402 SER D O   1 
ATOM   10894 C CB  . SER D 1 200 ? 6.801   26.351  60.322 1.00 30.09  ? 402 SER D CB  1 
ATOM   10895 O OG  . SER D 1 200 ? 5.702   27.012  59.730 1.00 31.70  ? 402 SER D OG  1 
ATOM   10896 N N   . GLN D 1 201 ? 6.864   27.617  63.094 1.00 36.72  ? 403 GLN D N   1 
ATOM   10897 C CA  . GLN D 1 201 ? 6.575   28.654  64.072 1.00 36.49  ? 403 GLN D CA  1 
ATOM   10898 C C   . GLN D 1 201 ? 6.534   30.019  63.401 1.00 36.32  ? 403 GLN D C   1 
ATOM   10899 O O   . GLN D 1 201 ? 7.419   30.364  62.614 1.00 36.76  ? 403 GLN D O   1 
ATOM   10900 C CB  . GLN D 1 201 ? 7.626   28.644  65.180 1.00 36.01  ? 403 GLN D CB  1 
ATOM   10901 C CG  . GLN D 1 201 ? 7.367   29.631  66.294 1.00 41.77  ? 403 GLN D CG  1 
ATOM   10902 C CD  . GLN D 1 201 ? 8.356   29.489  67.429 1.00 44.20  ? 403 GLN D CD  1 
ATOM   10903 O OE1 . GLN D 1 201 ? 9.162   28.559  67.449 1.00 45.37  ? 403 GLN D OE1 1 
ATOM   10904 N NE2 . GLN D 1 201 ? 8.311   30.419  68.377 1.00 45.16  ? 403 GLN D NE2 1 
ATOM   10905 N N   . MET D 1 202 ? 5.506   30.798  63.725 1.00 42.62  ? 404 MET D N   1 
ATOM   10906 C CA  . MET D 1 202 ? 5.262   32.090  63.096 1.00 42.25  ? 404 MET D CA  1 
ATOM   10907 C C   . MET D 1 202 ? 5.613   33.204  64.073 1.00 42.03  ? 404 MET D C   1 
ATOM   10908 O O   . MET D 1 202 ? 5.064   33.260  65.178 1.00 43.45  ? 404 MET D O   1 
ATOM   10909 C CB  . MET D 1 202 ? 3.805   32.205  62.652 1.00 39.93  ? 404 MET D CB  1 
ATOM   10910 C CG  . MET D 1 202 ? 3.414   31.159  61.628 1.00 42.17  ? 404 MET D CG  1 
ATOM   10911 S SD  . MET D 1 202 ? 1.703   31.279  61.092 1.00 45.83  ? 404 MET D SD  1 
ATOM   10912 C CE  . MET D 1 202 ? 1.798   32.709  60.028 1.00 44.36  ? 404 MET D CE  1 
ATOM   10913 N N   . LEU D 1 203 ? 6.519   34.090  63.661 1.00 46.48  ? 405 LEU D N   1 
ATOM   10914 C CA  . LEU D 1 203 ? 7.099   35.099  64.540 1.00 46.38  ? 405 LEU D CA  1 
ATOM   10915 C C   . LEU D 1 203 ? 6.738   36.489  64.042 1.00 46.67  ? 405 LEU D C   1 
ATOM   10916 O O   . LEU D 1 203 ? 7.115   36.867  62.927 1.00 46.94  ? 405 LEU D O   1 
ATOM   10917 C CB  . LEU D 1 203 ? 8.620   34.964  64.607 1.00 45.07  ? 405 LEU D CB  1 
ATOM   10918 C CG  . LEU D 1 203 ? 9.279   33.938  65.523 1.00 42.99  ? 405 LEU D CG  1 
ATOM   10919 C CD1 . LEU D 1 203 ? 9.011   32.531  65.041 1.00 41.03  ? 405 LEU D CD1 1 
ATOM   10920 C CD2 . LEU D 1 203 ? 10.763  34.204  65.582 1.00 42.34  ? 405 LEU D CD2 1 
ATOM   10921 N N   . ARG D 1 204 ? 6.034   37.255  64.871 1.00 51.17  ? 406 ARG D N   1 
ATOM   10922 C CA  . ARG D 1 204 ? 5.915   38.684  64.643 1.00 52.95  ? 406 ARG D CA  1 
ATOM   10923 C C   . ARG D 1 204 ? 7.194   39.378  65.103 1.00 54.44  ? 406 ARG D C   1 
ATOM   10924 O O   . ARG D 1 204 ? 8.139   38.746  65.579 1.00 54.40  ? 406 ARG D O   1 
ATOM   10925 C CB  . ARG D 1 204 ? 4.686   39.259  65.347 1.00 51.03  ? 406 ARG D CB  1 
ATOM   10926 C CG  . ARG D 1 204 ? 3.367   38.874  64.709 1.00 50.86  ? 406 ARG D CG  1 
ATOM   10927 C CD  . ARG D 1 204 ? 2.198   39.590  65.361 1.00 50.60  ? 406 ARG D CD  1 
ATOM   10928 N NE  . ARG D 1 204 ? 0.930   39.260  64.718 1.00 54.71  ? 406 ARG D NE  1 
ATOM   10929 C CZ  . ARG D 1 204 ? -0.255  39.690  65.138 1.00 55.36  ? 406 ARG D CZ  1 
ATOM   10930 N NH1 . ARG D 1 204 ? -0.338  40.468  66.205 1.00 56.10  ? 406 ARG D NH1 1 
ATOM   10931 N NH2 . ARG D 1 204 ? -1.357  39.343  64.491 1.00 55.53  ? 406 ARG D NH2 1 
ATOM   10932 N N   . THR D 1 205 ? 7.221   40.704  64.973 1.00 54.10  ? 407 THR D N   1 
ATOM   10933 C CA  . THR D 1 205 ? 8.448   41.453  65.217 1.00 55.65  ? 407 THR D CA  1 
ATOM   10934 C C   . THR D 1 205 ? 8.911   41.390  66.668 1.00 56.71  ? 407 THR D C   1 
ATOM   10935 O O   . THR D 1 205 ? 10.048  41.775  66.954 1.00 61.98  ? 407 THR D O   1 
ATOM   10936 C CB  . THR D 1 205 ? 8.262   42.909  64.794 1.00 56.03  ? 407 THR D CB  1 
ATOM   10937 O OG1 . THR D 1 205 ? 9.517   43.595  64.870 1.00 59.35  ? 407 THR D OG1 1 
ATOM   10938 C CG2 . THR D 1 205 ? 7.252   43.599  65.694 1.00 54.90  ? 407 THR D CG2 1 
ATOM   10939 N N   . GLY D 1 206 ? 8.068   40.926  67.588 1.00 58.84  ? 408 GLY D N   1 
ATOM   10940 C CA  . GLY D 1 206 ? 8.478   40.780  68.971 1.00 58.77  ? 408 GLY D CA  1 
ATOM   10941 C C   . GLY D 1 206 ? 8.805   39.374  69.421 1.00 57.35  ? 408 GLY D C   1 
ATOM   10942 O O   . GLY D 1 206 ? 9.406   39.199  70.484 1.00 58.23  ? 408 GLY D O   1 
ATOM   10943 N N   . ASN D 1 207 ? 8.421   38.364  68.647 1.00 55.75  ? 409 ASN D N   1 
ATOM   10944 C CA  . ASN D 1 207 ? 8.697   36.980  68.997 1.00 54.65  ? 409 ASN D CA  1 
ATOM   10945 C C   . ASN D 1 207 ? 10.124  36.599  68.616 1.00 54.15  ? 409 ASN D C   1 
ATOM   10946 O O   . ASN D 1 207 ? 10.736  37.188  67.723 1.00 54.40  ? 409 ASN D O   1 
ATOM   10947 C CB  . ASN D 1 207 ? 7.702   36.045  68.312 1.00 53.99  ? 409 ASN D CB  1 
ATOM   10948 C CG  . ASN D 1 207 ? 6.280   36.259  68.789 1.00 54.12  ? 409 ASN D CG  1 
ATOM   10949 O OD1 . ASN D 1 207 ? 5.361   36.407  67.988 1.00 55.24  ? 409 ASN D OD1 1 
ATOM   10950 N ND2 . ASN D 1 207 ? 6.092   36.269  70.100 1.00 54.90  ? 409 ASN D ND2 1 
ATOM   10951 N N   . ASN D 1 208 ? 10.652  35.592  69.310 1.00 48.76  ? 410 ASN D N   1 
ATOM   10952 C CA  . ASN D 1 208 ? 11.978  35.062  69.028 1.00 48.43  ? 410 ASN D CA  1 
ATOM   10953 C C   . ASN D 1 208 ? 11.911  33.546  68.900 1.00 48.53  ? 410 ASN D C   1 
ATOM   10954 O O   . ASN D 1 208 ? 10.922  32.908  69.267 1.00 48.77  ? 410 ASN D O   1 
ATOM   10955 C CB  . ASN D 1 208 ? 12.998  35.485  70.098 1.00 52.46  ? 410 ASN D CB  1 
ATOM   10956 C CG  . ASN D 1 208 ? 12.610  35.047  71.499 1.00 53.43  ? 410 ASN D CG  1 
ATOM   10957 O OD1 . ASN D 1 208 ? 11.983  34.008  71.695 1.00 56.45  ? 410 ASN D OD1 1 
ATOM   10958 N ND2 . ASN D 1 208 ? 12.992  35.845  72.486 1.00 53.93  ? 410 ASN D ND2 1 
ATOM   10959 N N   . PHE D 1 209 ? 12.991  32.976  68.374 1.00 44.54  ? 411 PHE D N   1 
ATOM   10960 C CA  . PHE D 1 209 ? 13.057  31.570  68.006 1.00 45.40  ? 411 PHE D CA  1 
ATOM   10961 C C   . PHE D 1 209 ? 14.415  31.015  68.402 1.00 45.84  ? 411 PHE D C   1 
ATOM   10962 O O   . PHE D 1 209 ? 15.439  31.673  68.201 1.00 46.37  ? 411 PHE D O   1 
ATOM   10963 C CB  . PHE D 1 209 ? 12.836  31.405  66.495 1.00 40.96  ? 411 PHE D CB  1 
ATOM   10964 C CG  . PHE D 1 209 ? 12.997  29.999  65.998 1.00 41.66  ? 411 PHE D CG  1 
ATOM   10965 C CD1 . PHE D 1 209 ? 11.956  29.095  66.088 1.00 42.18  ? 411 PHE D CD1 1 
ATOM   10966 C CD2 . PHE D 1 209 ? 14.187  29.587  65.425 1.00 41.34  ? 411 PHE D CD2 1 
ATOM   10967 C CE1 . PHE D 1 209 ? 12.103  27.805  65.621 1.00 41.37  ? 411 PHE D CE1 1 
ATOM   10968 C CE2 . PHE D 1 209 ? 14.337  28.301  64.959 1.00 41.90  ? 411 PHE D CE2 1 
ATOM   10969 C CZ  . PHE D 1 209 ? 13.294  27.409  65.057 1.00 41.28  ? 411 PHE D CZ  1 
ATOM   10970 N N   . GLN D 1 210 ? 14.426  29.808  68.963 1.00 42.54  ? 412 GLN D N   1 
ATOM   10971 C CA  . GLN D 1 210 ? 15.688  29.145  69.255 1.00 45.13  ? 412 GLN D CA  1 
ATOM   10972 C C   . GLN D 1 210 ? 15.476  27.642  69.314 1.00 44.25  ? 412 GLN D C   1 
ATOM   10973 O O   . GLN D 1 210 ? 14.357  27.155  69.488 1.00 45.17  ? 412 GLN D O   1 
ATOM   10974 C CB  . GLN D 1 210 ? 16.309  29.634  70.568 1.00 44.24  ? 412 GLN D CB  1 
ATOM   10975 C CG  . GLN D 1 210 ? 15.525  29.271  71.811 1.00 52.80  ? 412 GLN D CG  1 
ATOM   10976 C CD  . GLN D 1 210 ? 16.208  29.743  73.080 1.00 60.44  ? 412 GLN D CD  1 
ATOM   10977 O OE1 . GLN D 1 210 ? 17.052  30.638  73.048 1.00 63.30  ? 412 GLN D OE1 1 
ATOM   10978 N NE2 . GLN D 1 210 ? 15.849  29.138  74.205 1.00 61.84  ? 412 GLN D NE2 1 
ATOM   10979 N N   . PHE D 1 211 ? 16.576  26.911  69.155 1.00 43.28  ? 413 PHE D N   1 
ATOM   10980 C CA  . PHE D 1 211 ? 16.585  25.472  69.360 1.00 42.40  ? 413 PHE D CA  1 
ATOM   10981 C C   . PHE D 1 211 ? 18.017  25.057  69.644 1.00 42.05  ? 413 PHE D C   1 
ATOM   10982 O O   . PHE D 1 211 ? 18.962  25.796  69.359 1.00 41.20  ? 413 PHE D O   1 
ATOM   10983 C CB  . PHE D 1 211 ? 16.039  24.713  68.146 1.00 38.82  ? 413 PHE D CB  1 
ATOM   10984 C CG  . PHE D 1 211 ? 16.927  24.776  66.944 1.00 39.40  ? 413 PHE D CG  1 
ATOM   10985 C CD1 . PHE D 1 211 ? 17.880  23.797  66.725 1.00 40.23  ? 413 PHE D CD1 1 
ATOM   10986 C CD2 . PHE D 1 211 ? 16.827  25.814  66.044 1.00 40.27  ? 413 PHE D CD2 1 
ATOM   10987 C CE1 . PHE D 1 211 ? 18.707  23.847  65.631 1.00 40.10  ? 413 PHE D CE1 1 
ATOM   10988 C CE2 . PHE D 1 211 ? 17.655  25.868  64.949 1.00 41.14  ? 413 PHE D CE2 1 
ATOM   10989 C CZ  . PHE D 1 211 ? 18.596  24.880  64.742 1.00 41.09  ? 413 PHE D CZ  1 
ATOM   10990 N N   . SER D 1 212 ? 18.170  23.862  70.200 1.00 42.11  ? 414 SER D N   1 
ATOM   10991 C CA  . SER D 1 212 ? 19.484  23.299  70.459 1.00 41.81  ? 414 SER D CA  1 
ATOM   10992 C C   . SER D 1 212 ? 19.675  22.048  69.614 1.00 41.43  ? 414 SER D C   1 
ATOM   10993 O O   . SER D 1 212 ? 18.714  21.380  69.227 1.00 41.54  ? 414 SER D O   1 
ATOM   10994 C CB  . SER D 1 212 ? 19.673  22.976  71.946 1.00 50.12  ? 414 SER D CB  1 
ATOM   10995 O OG  . SER D 1 212 ? 18.756  21.984  72.375 1.00 54.94  ? 414 SER D OG  1 
ATOM   10996 N N   . TYR D 1 213 ? 20.937  21.742  69.327 1.00 39.82  ? 415 TYR D N   1 
ATOM   10997 C CA  . TYR D 1 213 ? 21.299  20.578  68.534 1.00 40.12  ? 415 TYR D CA  1 
ATOM   10998 C C   . TYR D 1 213 ? 22.547  19.936  69.121 1.00 42.03  ? 415 TYR D C   1 
ATOM   10999 O O   . TYR D 1 213 ? 23.461  20.624  69.579 1.00 41.95  ? 415 TYR D O   1 
ATOM   11000 C CB  . TYR D 1 213 ? 21.541  20.945  67.063 1.00 36.45  ? 415 TYR D CB  1 
ATOM   11001 C CG  . TYR D 1 213 ? 22.085  19.804  66.238 1.00 36.78  ? 415 TYR D CG  1 
ATOM   11002 C CD1 . TYR D 1 213 ? 21.257  18.783  65.798 1.00 35.13  ? 415 TYR D CD1 1 
ATOM   11003 C CD2 . TYR D 1 213 ? 23.429  19.746  65.905 1.00 37.72  ? 415 TYR D CD2 1 
ATOM   11004 C CE1 . TYR D 1 213 ? 21.754  17.740  65.051 1.00 36.91  ? 415 TYR D CE1 1 
ATOM   11005 C CE2 . TYR D 1 213 ? 23.933  18.707  65.160 1.00 37.66  ? 415 TYR D CE2 1 
ATOM   11006 C CZ  . TYR D 1 213 ? 23.092  17.709  64.736 1.00 38.11  ? 415 TYR D CZ  1 
ATOM   11007 O OH  . TYR D 1 213 ? 23.595  16.672  63.993 1.00 40.53  ? 415 TYR D OH  1 
ATOM   11008 N N   . GLU D 1 214 ? 22.578  18.608  69.093 1.00 39.66  ? 416 GLU D N   1 
ATOM   11009 C CA  . GLU D 1 214 ? 23.686  17.824  69.622 1.00 42.28  ? 416 GLU D CA  1 
ATOM   11010 C C   . GLU D 1 214 ? 24.412  17.152  68.466 1.00 41.01  ? 416 GLU D C   1 
ATOM   11011 O O   . GLU D 1 214 ? 23.800  16.402  67.700 1.00 41.67  ? 416 GLU D O   1 
ATOM   11012 C CB  . GLU D 1 214 ? 23.180  16.780  70.617 1.00 40.52  ? 416 GLU D CB  1 
ATOM   11013 C CG  . GLU D 1 214 ? 24.265  15.962  71.301 1.00 52.12  ? 416 GLU D CG  1 
ATOM   11014 C CD  . GLU D 1 214 ? 25.086  16.773  72.281 1.00 58.45  ? 416 GLU D CD  1 
ATOM   11015 O OE1 . GLU D 1 214 ? 24.663  17.894  72.633 1.00 60.27  ? 416 GLU D OE1 1 
ATOM   11016 O OE2 . GLU D 1 214 ? 26.155  16.286  72.706 1.00 62.60  ? 416 GLU D OE2 1 
ATOM   11017 N N   . PHE D 1 215 ? 25.707  17.424  68.338 1.00 43.14  ? 417 PHE D N   1 
ATOM   11018 C CA  . PHE D 1 215 ? 26.517  16.729  67.347 1.00 43.07  ? 417 PHE D CA  1 
ATOM   11019 C C   . PHE D 1 215 ? 26.718  15.274  67.741 1.00 45.83  ? 417 PHE D C   1 
ATOM   11020 O O   . PHE D 1 215 ? 27.125  14.966  68.864 1.00 45.40  ? 417 PHE D O   1 
ATOM   11021 C CB  . PHE D 1 215 ? 27.877  17.408  67.187 1.00 46.18  ? 417 PHE D CB  1 
ATOM   11022 C CG  . PHE D 1 215 ? 27.823  18.727  66.481 1.00 43.18  ? 417 PHE D CG  1 
ATOM   11023 C CD1 . PHE D 1 215 ? 27.919  18.790  65.104 1.00 41.62  ? 417 PHE D CD1 1 
ATOM   11024 C CD2 . PHE D 1 215 ? 27.674  19.903  67.188 1.00 42.38  ? 417 PHE D CD2 1 
ATOM   11025 C CE1 . PHE D 1 215 ? 27.877  19.997  64.449 1.00 40.54  ? 417 PHE D CE1 1 
ATOM   11026 C CE2 . PHE D 1 215 ? 27.627  21.114  66.537 1.00 40.84  ? 417 PHE D CE2 1 
ATOM   11027 C CZ  . PHE D 1 215 ? 27.727  21.161  65.166 1.00 40.65  ? 417 PHE D CZ  1 
ATOM   11028 N N   . GLU D 1 216 ? 26.433  14.374  66.807 1.00 40.81  ? 418 GLU D N   1 
ATOM   11029 C CA  . GLU D 1 216 ? 26.726  12.970  67.031 1.00 44.89  ? 418 GLU D CA  1 
ATOM   11030 C C   . GLU D 1 216 ? 28.233  12.745  66.998 1.00 44.94  ? 418 GLU D C   1 
ATOM   11031 O O   . GLU D 1 216 ? 28.996  13.553  66.463 1.00 44.53  ? 418 GLU D O   1 
ATOM   11032 C CB  . GLU D 1 216 ? 26.025  12.096  65.992 1.00 32.78  ? 418 GLU D CB  1 
ATOM   11033 C CG  . GLU D 1 216 ? 26.463  12.340  64.565 1.00 40.03  ? 418 GLU D CG  1 
ATOM   11034 C CD  . GLU D 1 216 ? 25.639  11.549  63.573 1.00 45.08  ? 418 GLU D CD  1 
ATOM   11035 O OE1 . GLU D 1 216 ? 24.958  10.592  63.997 1.00 48.45  ? 418 GLU D OE1 1 
ATOM   11036 O OE2 . GLU D 1 216 ? 25.667  11.879  62.371 1.00 46.84  ? 418 GLU D OE2 1 
ATOM   11037 N N   . ASN D 1 217 ? 28.660  11.636  67.596 1.00 48.71  ? 419 ASN D N   1 
ATOM   11038 C CA  . ASN D 1 217 ? 30.084  11.382  67.761 1.00 49.88  ? 419 ASN D CA  1 
ATOM   11039 C C   . ASN D 1 217 ? 30.781  11.288  66.410 1.00 48.65  ? 419 ASN D C   1 
ATOM   11040 O O   . ASN D 1 217 ? 30.395  10.492  65.549 1.00 49.20  ? 419 ASN D O   1 
ATOM   11041 C CB  . ASN D 1 217 ? 30.299  10.095  68.555 1.00 47.53  ? 419 ASN D CB  1 
ATOM   11042 C CG  . ASN D 1 217 ? 31.728  9.934   69.021 1.00 52.93  ? 419 ASN D CG  1 
ATOM   11043 O OD1 . ASN D 1 217 ? 32.420  10.917  69.282 1.00 55.91  ? 419 ASN D OD1 1 
ATOM   11044 N ND2 . ASN D 1 217 ? 32.182  8.690   69.125 1.00 55.27  ? 419 ASN D ND2 1 
ATOM   11045 N N   . VAL D 1 218 ? 31.811  12.108  66.232 1.00 49.58  ? 420 VAL D N   1 
ATOM   11046 C CA  . VAL D 1 218 ? 32.629  12.106  65.021 1.00 48.05  ? 420 VAL D CA  1 
ATOM   11047 C C   . VAL D 1 218 ? 34.089  12.200  65.441 1.00 46.69  ? 420 VAL D C   1 
ATOM   11048 O O   . VAL D 1 218 ? 34.406  12.737  66.513 1.00 46.69  ? 420 VAL D O   1 
ATOM   11049 C CB  . VAL D 1 218 ? 32.253  13.266  64.071 1.00 43.61  ? 420 VAL D CB  1 
ATOM   11050 C CG1 . VAL D 1 218 ? 30.837  13.101  63.553 1.00 46.58  ? 420 VAL D CG1 1 
ATOM   11051 C CG2 . VAL D 1 218 ? 32.415  14.599  64.776 1.00 44.75  ? 420 VAL D CG2 1 
ATOM   11052 N N   . PRO D 1 219 ? 35.002  11.681  64.625 1.00 48.36  ? 421 PRO D N   1 
ATOM   11053 C CA  . PRO D 1 219 ? 36.421  11.752  64.981 1.00 47.08  ? 421 PRO D CA  1 
ATOM   11054 C C   . PRO D 1 219 ? 36.969  13.162  64.842 1.00 46.34  ? 421 PRO D C   1 
ATOM   11055 O O   . PRO D 1 219 ? 36.446  13.987  64.090 1.00 46.95  ? 421 PRO D O   1 
ATOM   11056 C CB  . PRO D 1 219 ? 37.082  10.801  63.978 1.00 45.20  ? 421 PRO D CB  1 
ATOM   11057 C CG  . PRO D 1 219 ? 36.172  10.828  62.804 1.00 45.77  ? 421 PRO D CG  1 
ATOM   11058 C CD  . PRO D 1 219 ? 34.789  10.933  63.375 1.00 45.48  ? 421 PRO D CD  1 
ATOM   11059 N N   . PHE D 1 220 ? 38.065  13.427  65.551 1.00 48.38  ? 422 PHE D N   1 
ATOM   11060 C CA  . PHE D 1 220 ? 38.743  14.716  65.504 1.00 46.40  ? 422 PHE D CA  1 
ATOM   11061 C C   . PHE D 1 220 ? 39.392  14.906  64.148 1.00 46.07  ? 422 PHE D C   1 
ATOM   11062 O O   . PHE D 1 220 ? 39.970  13.972  63.609 1.00 46.01  ? 422 PHE D O   1 
ATOM   11063 C CB  . PHE D 1 220 ? 39.893  14.753  66.511 1.00 47.01  ? 422 PHE D CB  1 
ATOM   11064 C CG  . PHE D 1 220 ? 39.469  14.849  67.941 1.00 48.66  ? 422 PHE D CG  1 
ATOM   11065 C CD1 . PHE D 1 220 ? 39.103  16.063  68.485 1.00 48.62  ? 422 PHE D CD1 1 
ATOM   11066 C CD2 . PHE D 1 220 ? 39.483  13.734  68.752 1.00 48.69  ? 422 PHE D CD2 1 
ATOM   11067 C CE1 . PHE D 1 220 ? 38.727  16.158  69.808 1.00 48.46  ? 422 PHE D CE1 1 
ATOM   11068 C CE2 . PHE D 1 220 ? 39.110  13.822  70.076 1.00 47.85  ? 422 PHE D CE2 1 
ATOM   11069 C CZ  . PHE D 1 220 ? 38.730  15.036  70.605 1.00 48.11  ? 422 PHE D CZ  1 
ATOM   11070 N N   . HIS D 1 221 ? 39.305  16.107  63.589 1.00 44.63  ? 423 HIS D N   1 
ATOM   11071 C CA  . HIS D 1 221 ? 39.974  16.380  62.329 1.00 44.77  ? 423 HIS D CA  1 
ATOM   11072 C C   . HIS D 1 221 ? 41.444  16.405  62.678 1.00 45.46  ? 423 HIS D C   1 
ATOM   11073 O O   . HIS D 1 221 ? 41.818  16.971  63.702 1.00 45.64  ? 423 HIS D O   1 
ATOM   11074 C CB  . HIS D 1 221 ? 39.555  17.735  61.771 1.00 41.91  ? 423 HIS D CB  1 
ATOM   11075 C CG  . HIS D 1 221 ? 40.389  18.202  60.617 1.00 43.57  ? 423 HIS D CG  1 
ATOM   11076 N ND1 . HIS D 1 221 ? 40.269  17.676  59.350 1.00 44.67  ? 423 HIS D ND1 1 
ATOM   11077 C CD2 . HIS D 1 221 ? 41.345  19.157  60.538 1.00 43.90  ? 423 HIS D CD2 1 
ATOM   11078 C CE1 . HIS D 1 221 ? 41.120  18.281  58.542 1.00 45.29  ? 423 HIS D CE1 1 
ATOM   11079 N NE2 . HIS D 1 221 ? 41.784  19.185  59.238 1.00 45.14  ? 423 HIS D NE2 1 
ATOM   11080 N N   . SER D 1 222 ? 42.293  15.824  61.840 1.00 46.05  ? 424 SER D N   1 
ATOM   11081 C CA  . SER D 1 222 ? 43.714  15.818  62.163 1.00 46.37  ? 424 SER D CA  1 
ATOM   11082 C C   . SER D 1 222 ? 44.442  17.015  61.567 1.00 45.80  ? 424 SER D C   1 
ATOM   11083 O O   . SER D 1 222 ? 44.814  17.016  60.398 1.00 46.47  ? 424 SER D O   1 
ATOM   11084 C CB  . SER D 1 222 ? 44.364  14.516  61.700 1.00 45.40  ? 424 SER D CB  1 
ATOM   11085 O OG  . SER D 1 222 ? 44.253  14.365  60.300 1.00 48.99  ? 424 SER D OG  1 
ATOM   11086 N N   . SER D 1 223 ? 44.646  18.032  62.395 1.00 46.55  ? 425 SER D N   1 
ATOM   11087 C CA  . SER D 1 223 ? 45.336  19.236  61.976 1.00 46.20  ? 425 SER D CA  1 
ATOM   11088 C C   . SER D 1 223 ? 46.834  19.140  62.199 1.00 45.37  ? 425 SER D C   1 
ATOM   11089 O O   . SER D 1 223 ? 47.377  19.848  63.040 1.00 46.08  ? 425 SER D O   1 
ATOM   11090 C CB  . SER D 1 223 ? 44.791  20.435  62.742 1.00 47.66  ? 425 SER D CB  1 
ATOM   11091 O OG  . SER D 1 223 ? 45.115  20.335  64.112 1.00 49.81  ? 425 SER D OG  1 
ATOM   11092 N N   . TYR D 1 224 ? 47.500  18.262  61.460 1.00 45.36  ? 426 TYR D N   1 
ATOM   11093 C CA  . TYR D 1 224 ? 48.945  18.101  61.580 1.00 45.80  ? 426 TYR D CA  1 
ATOM   11094 C C   . TYR D 1 224 ? 49.532  17.438  60.351 1.00 45.73  ? 426 TYR D C   1 
ATOM   11095 O O   . TYR D 1 224 ? 48.818  16.850  59.546 1.00 46.10  ? 426 TYR D O   1 
ATOM   11096 C CB  . TYR D 1 224 ? 49.322  17.295  62.824 1.00 44.40  ? 426 TYR D CB  1 
ATOM   11097 C CG  . TYR D 1 224 ? 48.631  15.968  62.900 1.00 45.78  ? 426 TYR D CG  1 
ATOM   11098 C CD1 . TYR D 1 224 ? 48.981  14.935  62.051 1.00 46.24  ? 426 TYR D CD1 1 
ATOM   11099 C CD2 . TYR D 1 224 ? 47.615  15.752  63.813 1.00 46.58  ? 426 TYR D CD2 1 
ATOM   11100 C CE1 . TYR D 1 224 ? 48.339  13.719  62.111 1.00 48.56  ? 426 TYR D CE1 1 
ATOM   11101 C CE2 . TYR D 1 224 ? 46.968  14.541  63.882 1.00 48.58  ? 426 TYR D CE2 1 
ATOM   11102 C CZ  . TYR D 1 224 ? 47.334  13.530  63.027 1.00 49.45  ? 426 TYR D CZ  1 
ATOM   11103 O OH  . TYR D 1 224 ? 46.687  12.324  63.098 1.00 50.76  ? 426 TYR D OH  1 
ATOM   11104 N N   . ALA D 1 225 ? 50.844  17.541  60.216 1.00 44.63  ? 427 ALA D N   1 
ATOM   11105 C CA  . ALA D 1 225 ? 51.558  16.926  59.116 1.00 44.60  ? 427 ALA D CA  1 
ATOM   11106 C C   . ALA D 1 225 ? 52.476  15.891  59.745 1.00 45.29  ? 427 ALA D C   1 
ATOM   11107 O O   . ALA D 1 225 ? 53.118  16.169  60.748 1.00 45.95  ? 427 ALA D O   1 
ATOM   11108 C CB  . ALA D 1 225 ? 52.355  17.965  58.354 1.00 45.26  ? 427 ALA D CB  1 
ATOM   11109 N N   . HIS D 1 226 ? 52.510  14.685  59.197 1.00 47.02  ? 428 HIS D N   1 
ATOM   11110 C CA  . HIS D 1 226 ? 53.358  13.655  59.768 1.00 47.06  ? 428 HIS D CA  1 
ATOM   11111 C C   . HIS D 1 226 ? 54.839  13.958  59.597 1.00 47.52  ? 428 HIS D C   1 
ATOM   11112 O O   . HIS D 1 226 ? 55.287  14.328  58.517 1.00 46.23  ? 428 HIS D O   1 
ATOM   11113 C CB  . HIS D 1 226 ? 53.045  12.307  59.133 1.00 47.24  ? 428 HIS D CB  1 
ATOM   11114 C CG  . HIS D 1 226 ? 51.710  11.754  59.513 1.00 48.38  ? 428 HIS D CG  1 
ATOM   11115 N ND1 . HIS D 1 226 ? 51.470  11.163  60.735 1.00 47.96  ? 428 HIS D ND1 1 
ATOM   11116 C CD2 . HIS D 1 226 ? 50.546  11.688  58.828 1.00 49.00  ? 428 HIS D CD2 1 
ATOM   11117 C CE1 . HIS D 1 226 ? 50.213  10.761  60.788 1.00 48.38  ? 428 HIS D CE1 1 
ATOM   11118 N NE2 . HIS D 1 226 ? 49.631  11.069  59.644 1.00 50.01  ? 428 HIS D NE2 1 
ATOM   11119 N N   . SER D 1 227 ? 55.587  13.819  60.684 1.00 48.05  ? 429 SER D N   1 
ATOM   11120 C CA  . SER D 1 227 ? 57.030  14.020  60.671 1.00 49.11  ? 429 SER D CA  1 
ATOM   11121 C C   . SER D 1 227 ? 57.735  12.944  59.841 1.00 49.29  ? 429 SER D C   1 
ATOM   11122 O O   . SER D 1 227 ? 58.699  13.221  59.131 1.00 49.83  ? 429 SER D O   1 
ATOM   11123 C CB  . SER D 1 227 ? 57.585  14.074  62.093 1.00 48.57  ? 429 SER D CB  1 
ATOM   11124 O OG  . SER D 1 227 ? 57.348  12.864  62.784 1.00 52.69  ? 429 SER D OG  1 
ATOM   11125 N N   . GLN D 1 228 ? 57.247  11.711  59.953 1.00 47.33  ? 430 GLN D N   1 
ATOM   11126 C CA  . GLN D 1 228 ? 57.814  10.575  59.236 1.00 48.63  ? 430 GLN D CA  1 
ATOM   11127 C C   . GLN D 1 228 ? 57.037  10.223  57.979 1.00 48.23  ? 430 GLN D C   1 
ATOM   11128 O O   . GLN D 1 228 ? 55.862  10.549  57.853 1.00 48.09  ? 430 GLN D O   1 
ATOM   11129 C CB  . GLN D 1 228 ? 57.817  9.345   60.134 1.00 49.73  ? 430 GLN D CB  1 
ATOM   11130 C CG  . GLN D 1 228 ? 58.635  9.476   61.398 1.00 50.48  ? 430 GLN D CG  1 
ATOM   11131 C CD  . GLN D 1 228 ? 58.475  8.270   62.294 1.00 51.02  ? 430 GLN D CD  1 
ATOM   11132 O OE1 . GLN D 1 228 ? 57.589  8.228   63.142 1.00 51.79  ? 430 GLN D OE1 1 
ATOM   11133 N NE2 . GLN D 1 228 ? 59.337  7.280   62.110 1.00 49.04  ? 430 GLN D NE2 1 
ATOM   11134 N N   . SER D 1 229 ? 57.701  9.539   57.055 1.00 47.21  ? 431 SER D N   1 
ATOM   11135 C CA  . SER D 1 229 ? 57.060  9.107   55.825 1.00 47.03  ? 431 SER D CA  1 
ATOM   11136 C C   . SER D 1 229 ? 56.790  7.610   55.888 1.00 46.77  ? 431 SER D C   1 
ATOM   11137 O O   . SER D 1 229 ? 57.534  6.853   56.516 1.00 46.06  ? 431 SER D O   1 
ATOM   11138 C CB  . SER D 1 229 ? 57.915  9.436   54.599 1.00 44.85  ? 431 SER D CB  1 
ATOM   11139 O OG  . SER D 1 229 ? 59.132  8.722   54.620 1.00 49.33  ? 431 SER D OG  1 
ATOM   11140 N N   . LEU D 1 230 ? 55.694  7.201   55.243 1.00 45.63  ? 432 LEU D N   1 
ATOM   11141 C CA  . LEU D 1 230 ? 55.235  5.818   55.315 1.00 45.02  ? 432 LEU D CA  1 
ATOM   11142 C C   . LEU D 1 230 ? 56.342  4.827   54.981 1.00 45.95  ? 432 LEU D C   1 
ATOM   11143 O O   . LEU D 1 230 ? 56.420  3.756   55.595 1.00 46.25  ? 432 LEU D O   1 
ATOM   11144 C CB  . LEU D 1 230 ? 54.053  5.625   54.368 1.00 40.41  ? 432 LEU D CB  1 
ATOM   11145 C CG  . LEU D 1 230 ? 53.239  4.337   54.451 1.00 41.15  ? 432 LEU D CG  1 
ATOM   11146 C CD1 . LEU D 1 230 ? 53.171  3.835   55.879 1.00 40.83  ? 432 LEU D CD1 1 
ATOM   11147 C CD2 . LEU D 1 230 ? 51.846  4.597   53.930 1.00 41.53  ? 432 LEU D CD2 1 
ATOM   11148 N N   . ASP D 1 231 ? 57.203  5.156   54.024 1.00 47.59  ? 433 ASP D N   1 
ATOM   11149 C CA  . ASP D 1 231 ? 58.268  4.253   53.612 1.00 49.66  ? 433 ASP D CA  1 
ATOM   11150 C C   . ASP D 1 231 ? 59.475  4.271   54.545 1.00 48.98  ? 433 ASP D C   1 
ATOM   11151 O O   . ASP D 1 231 ? 60.143  3.243   54.682 1.00 50.05  ? 433 ASP D O   1 
ATOM   11152 C CB  . ASP D 1 231 ? 58.710  4.579   52.181 1.00 48.56  ? 433 ASP D CB  1 
ATOM   11153 C CG  . ASP D 1 231 ? 59.196  6.001   52.029 1.00 52.79  ? 433 ASP D CG  1 
ATOM   11154 O OD1 . ASP D 1 231 ? 59.069  6.781   52.993 1.00 54.84  ? 433 ASP D OD1 1 
ATOM   11155 O OD2 . ASP D 1 231 ? 59.706  6.343   50.943 1.00 56.23  ? 433 ASP D OD2 1 
ATOM   11156 N N   . ARG D 1 232 ? 59.757  5.396   55.199 1.00 50.24  ? 434 ARG D N   1 
ATOM   11157 C CA  . ARG D 1 232 ? 60.964  5.580   55.999 1.00 48.58  ? 434 ARG D CA  1 
ATOM   11158 C C   . ARG D 1 232 ? 60.778  5.256   57.478 1.00 48.30  ? 434 ARG D C   1 
ATOM   11159 O O   . ARG D 1 232 ? 61.650  5.593   58.285 1.00 48.14  ? 434 ARG D O   1 
ATOM   11160 C CB  . ARG D 1 232 ? 61.505  6.997   55.819 1.00 47.43  ? 434 ARG D CB  1 
ATOM   11161 C CG  . ARG D 1 232 ? 62.010  7.257   54.410 1.00 49.47  ? 434 ARG D CG  1 
ATOM   11162 C CD  . ARG D 1 232 ? 63.306  6.494   54.159 1.00 48.08  ? 434 ARG D CD  1 
ATOM   11163 N NE  . ARG D 1 232 ? 63.854  6.729   52.826 1.00 48.00  ? 434 ARG D NE  1 
ATOM   11164 C CZ  . ARG D 1 232 ? 63.646  5.940   51.777 1.00 47.96  ? 434 ARG D CZ  1 
ATOM   11165 N NH1 . ARG D 1 232 ? 62.909  4.846   51.900 1.00 46.84  ? 434 ARG D NH1 1 
ATOM   11166 N NH2 . ARG D 1 232 ? 64.184  6.240   50.605 1.00 50.01  ? 434 ARG D NH2 1 
ATOM   11167 N N   . LEU D 1 233 ? 59.656  4.643   57.863 1.00 45.93  ? 435 LEU D N   1 
ATOM   11168 C CA  . LEU D 1 233 ? 59.394  4.298   59.259 1.00 45.79  ? 435 LEU D CA  1 
ATOM   11169 C C   . LEU D 1 233 ? 60.417  3.331   59.846 1.00 46.59  ? 435 LEU D C   1 
ATOM   11170 O O   . LEU D 1 233 ? 60.359  3.050   61.047 1.00 47.46  ? 435 LEU D O   1 
ATOM   11171 C CB  . LEU D 1 233 ? 57.999  3.687   59.393 1.00 43.75  ? 435 LEU D CB  1 
ATOM   11172 C CG  . LEU D 1 233 ? 56.800  4.573   59.064 1.00 44.28  ? 435 LEU D CG  1 
ATOM   11173 C CD1 . LEU D 1 233 ? 55.519  3.762   59.125 1.00 42.12  ? 435 LEU D CD1 1 
ATOM   11174 C CD2 . LEU D 1 233 ? 56.736  5.743   60.019 1.00 43.75  ? 435 LEU D CD2 1 
ATOM   11175 N N   . MET D 1 234 ? 61.331  2.811   59.036 1.00 46.86  ? 436 MET D N   1 
ATOM   11176 C CA  . MET D 1 234 ? 62.349  1.860   59.452 1.00 47.92  ? 436 MET D CA  1 
ATOM   11177 C C   . MET D 1 234 ? 63.354  2.490   60.416 1.00 48.02  ? 436 MET D C   1 
ATOM   11178 O O   . MET D 1 234 ? 63.471  3.712   60.531 1.00 47.99  ? 436 MET D O   1 
ATOM   11179 C CB  . MET D 1 234 ? 63.100  1.341   58.233 1.00 47.89  ? 436 MET D CB  1 
ATOM   11180 C CG  . MET D 1 234 ? 63.946  2.424   57.604 1.00 49.94  ? 436 MET D CG  1 
ATOM   11181 S SD  . MET D 1 234 ? 64.546  2.027   55.963 1.00 54.57  ? 436 MET D SD  1 
ATOM   11182 C CE  . MET D 1 234 ? 63.159  2.555   54.971 1.00 53.95  ? 436 MET D CE  1 
ATOM   11183 N N   . ASN D 1 235 ? 64.073  1.625   61.124 1.00 49.10  ? 437 ASN D N   1 
ATOM   11184 C CA  . ASN D 1 235 ? 65.235  2.041   61.904 1.00 47.79  ? 437 ASN D CA  1 
ATOM   11185 C C   . ASN D 1 235 ? 66.502  1.779   61.098 1.00 47.11  ? 437 ASN D C   1 
ATOM   11186 O O   . ASN D 1 235 ? 66.781  0.621   60.766 1.00 47.46  ? 437 ASN D O   1 
ATOM   11187 C CB  . ASN D 1 235 ? 65.297  1.282   63.225 1.00 46.68  ? 437 ASN D CB  1 
ATOM   11188 C CG  . ASN D 1 235 ? 66.413  1.772   64.141 1.00 47.21  ? 437 ASN D CG  1 
ATOM   11189 O OD1 . ASN D 1 235 ? 67.353  2.441   63.712 1.00 47.51  ? 437 ASN D OD1 1 
ATOM   11190 N ND2 . ASN D 1 235 ? 66.316  1.420   65.414 1.00 46.91  ? 437 ASN D ND2 1 
ATOM   11191 N N   . PRO D 1 236 ? 67.297  2.808   60.771 1.00 44.90  ? 438 PRO D N   1 
ATOM   11192 C CA  . PRO D 1 236 ? 68.531  2.607   60.008 1.00 44.23  ? 438 PRO D CA  1 
ATOM   11193 C C   . PRO D 1 236 ? 69.717  2.245   60.897 1.00 44.40  ? 438 PRO D C   1 
ATOM   11194 O O   . PRO D 1 236 ? 70.212  1.119   60.822 1.00 45.01  ? 438 PRO D O   1 
ATOM   11195 C CB  . PRO D 1 236 ? 68.745  3.963   59.343 1.00 40.72  ? 438 PRO D CB  1 
ATOM   11196 C CG  . PRO D 1 236 ? 68.164  4.930   60.306 1.00 41.23  ? 438 PRO D CG  1 
ATOM   11197 C CD  . PRO D 1 236 ? 67.009  4.236   60.982 1.00 41.32  ? 438 PRO D CD  1 
ATOM   11198 N N   . GLN D 1 240 ? 67.258  -5.700  58.462 1.00 53.87  ? 442 GLN D N   1 
ATOM   11199 C CA  . GLN D 1 240 ? 66.191  -6.667  58.700 1.00 52.63  ? 442 GLN D CA  1 
ATOM   11200 C C   . GLN D 1 240 ? 66.669  -8.108  58.605 1.00 52.51  ? 442 GLN D C   1 
ATOM   11201 O O   . GLN D 1 240 ? 67.680  -8.402  57.974 1.00 52.48  ? 442 GLN D O   1 
ATOM   11202 C CB  . GLN D 1 240 ? 65.040  -6.462  57.711 1.00 51.08  ? 442 GLN D CB  1 
ATOM   11203 C CG  . GLN D 1 240 ? 64.208  -5.218  57.939 1.00 49.32  ? 442 GLN D CG  1 
ATOM   11204 C CD  . GLN D 1 240 ? 63.102  -5.079  56.915 1.00 49.45  ? 442 GLN D CD  1 
ATOM   11205 O OE1 . GLN D 1 240 ? 63.222  -5.556  55.789 1.00 48.36  ? 442 GLN D OE1 1 
ATOM   11206 N NE2 . GLN D 1 240 ? 62.004  -4.452  57.312 1.00 49.57  ? 442 GLN D NE2 1 
ATOM   11207 N N   . TYR D 1 241 ? 65.923  -9.005  59.244 1.00 50.87  ? 443 TYR D N   1 
ATOM   11208 C CA  . TYR D 1 241 ? 66.130  -10.435 59.082 1.00 49.43  ? 443 TYR D CA  1 
ATOM   11209 C C   . TYR D 1 241 ? 65.469  -10.989 57.827 1.00 49.06  ? 443 TYR D C   1 
ATOM   11210 O O   . TYR D 1 241 ? 65.705  -12.152 57.486 1.00 50.34  ? 443 TYR D O   1 
ATOM   11211 C CB  . TYR D 1 241 ? 65.625  -11.180 60.321 1.00 49.79  ? 443 TYR D CB  1 
ATOM   11212 C CG  . TYR D 1 241 ? 64.188  -10.893 60.693 1.00 49.35  ? 443 TYR D CG  1 
ATOM   11213 C CD1 . TYR D 1 241 ? 63.142  -11.612 60.134 1.00 48.95  ? 443 TYR D CD1 1 
ATOM   11214 C CD2 . TYR D 1 241 ? 63.880  -9.916  61.627 1.00 50.22  ? 443 TYR D CD2 1 
ATOM   11215 C CE1 . TYR D 1 241 ? 61.828  -11.350 60.484 1.00 49.11  ? 443 TYR D CE1 1 
ATOM   11216 C CE2 . TYR D 1 241 ? 62.573  -9.650  61.984 1.00 50.28  ? 443 TYR D CE2 1 
ATOM   11217 C CZ  . TYR D 1 241 ? 61.553  -10.368 61.410 1.00 49.90  ? 443 TYR D CZ  1 
ATOM   11218 O OH  . TYR D 1 241 ? 60.253  -10.103 61.766 1.00 49.73  ? 443 TYR D OH  1 
ATOM   11219 N N   . LEU D 1 242 ? 64.651  -10.195 57.143 1.00 49.85  ? 444 LEU D N   1 
ATOM   11220 C CA  . LEU D 1 242 ? 64.051  -10.614 55.887 1.00 50.00  ? 444 LEU D CA  1 
ATOM   11221 C C   . LEU D 1 242 ? 65.024  -10.435 54.727 1.00 50.61  ? 444 LEU D C   1 
ATOM   11222 O O   . LEU D 1 242 ? 65.940  -9.610  54.774 1.00 50.90  ? 444 LEU D O   1 
ATOM   11223 C CB  . LEU D 1 242 ? 62.768  -9.831  55.617 1.00 47.47  ? 444 LEU D CB  1 
ATOM   11224 C CG  . LEU D 1 242 ? 61.641  -10.068 56.619 1.00 46.89  ? 444 LEU D CG  1 
ATOM   11225 C CD1 . LEU D 1 242 ? 60.476  -9.153  56.318 1.00 46.16  ? 444 LEU D CD1 1 
ATOM   11226 C CD2 . LEU D 1 242 ? 61.200  -11.520 56.599 1.00 46.10  ? 444 LEU D CD2 1 
ATOM   11227 N N   . TYR D 1 243 ? 64.807  -11.218 53.674 1.00 48.65  ? 445 TYR D N   1 
ATOM   11228 C CA  . TYR D 1 243 ? 65.649  -11.226 52.489 1.00 48.67  ? 445 TYR D CA  1 
ATOM   11229 C C   . TYR D 1 243 ? 64.832  -10.865 51.255 1.00 48.70  ? 445 TYR D C   1 
ATOM   11230 O O   . TYR D 1 243 ? 63.601  -10.950 51.250 1.00 48.66  ? 445 TYR D O   1 
ATOM   11231 C CB  . TYR D 1 243 ? 66.309  -12.596 52.303 1.00 47.69  ? 445 TYR D CB  1 
ATOM   11232 C CG  . TYR D 1 243 ? 67.384  -12.891 53.318 1.00 49.88  ? 445 TYR D CG  1 
ATOM   11233 C CD1 . TYR D 1 243 ? 68.720  -12.679 53.019 1.00 51.07  ? 445 TYR D CD1 1 
ATOM   11234 C CD2 . TYR D 1 243 ? 67.062  -13.324 54.594 1.00 50.16  ? 445 TYR D CD2 1 
ATOM   11235 C CE1 . TYR D 1 243 ? 69.706  -12.936 53.944 1.00 51.83  ? 445 TYR D CE1 1 
ATOM   11236 C CE2 . TYR D 1 243 ? 68.042  -13.578 55.529 1.00 50.87  ? 445 TYR D CE2 1 
ATOM   11237 C CZ  . TYR D 1 243 ? 69.363  -13.381 55.200 1.00 51.57  ? 445 TYR D CZ  1 
ATOM   11238 O OH  . TYR D 1 243 ? 70.343  -13.632 56.131 1.00 52.71  ? 445 TYR D OH  1 
ATOM   11239 N N   . TYR D 1 244 ? 65.536  -10.442 50.206 1.00 51.18  ? 446 TYR D N   1 
ATOM   11240 C CA  . TYR D 1 244 ? 64.919  -10.122 48.927 1.00 51.53  ? 446 TYR D CA  1 
ATOM   11241 C C   . TYR D 1 244 ? 65.790  -10.690 47.817 1.00 51.89  ? 446 TYR D C   1 
ATOM   11242 O O   . TYR D 1 244 ? 66.934  -11.088 48.044 1.00 51.72  ? 446 TYR D O   1 
ATOM   11243 C CB  . TYR D 1 244 ? 64.721  -8.610  48.756 1.00 51.28  ? 446 TYR D CB  1 
ATOM   11244 C CG  . TYR D 1 244 ? 66.000  -7.809  48.647 1.00 51.66  ? 446 TYR D CG  1 
ATOM   11245 C CD1 . TYR D 1 244 ? 66.542  -7.495  47.407 1.00 50.66  ? 446 TYR D CD1 1 
ATOM   11246 C CD2 . TYR D 1 244 ? 66.672  -7.377  49.780 1.00 52.64  ? 446 TYR D CD2 1 
ATOM   11247 C CE1 . TYR D 1 244 ? 67.709  -6.766  47.301 1.00 52.45  ? 446 TYR D CE1 1 
ATOM   11248 C CE2 . TYR D 1 244 ? 67.842  -6.650  49.682 1.00 53.48  ? 446 TYR D CE2 1 
ATOM   11249 C CZ  . TYR D 1 244 ? 68.355  -6.348  48.440 1.00 53.79  ? 446 TYR D CZ  1 
ATOM   11250 O OH  . TYR D 1 244 ? 69.518  -5.622  48.337 1.00 54.39  ? 446 TYR D OH  1 
ATOM   11251 N N   . LEU D 1 245 ? 65.249  -10.715 46.602 1.00 53.29  ? 447 LEU D N   1 
ATOM   11252 C CA  . LEU D 1 245 ? 65.944  -11.301 45.460 1.00 54.96  ? 447 LEU D CA  1 
ATOM   11253 C C   . LEU D 1 245 ? 66.730  -10.199 44.759 1.00 56.84  ? 447 LEU D C   1 
ATOM   11254 O O   . LEU D 1 245 ? 66.147  -9.329  44.104 1.00 57.55  ? 447 LEU D O   1 
ATOM   11255 C CB  . LEU D 1 245 ? 64.943  -11.957 44.513 1.00 55.18  ? 447 LEU D CB  1 
ATOM   11256 C CG  . LEU D 1 245 ? 65.454  -12.625 43.236 1.00 55.48  ? 447 LEU D CG  1 
ATOM   11257 C CD1 . LEU D 1 245 ? 66.298  -13.840 43.561 1.00 54.43  ? 447 LEU D CD1 1 
ATOM   11258 C CD2 . LEU D 1 245 ? 64.295  -13.001 42.336 1.00 56.11  ? 447 LEU D CD2 1 
ATOM   11259 N N   . SER D 1 246 ? 68.056  -10.238 44.896 1.00 54.97  ? 448 SER D N   1 
ATOM   11260 C CA  . SER D 1 246 ? 68.918  -9.180  44.383 1.00 56.62  ? 448 SER D CA  1 
ATOM   11261 C C   . SER D 1 246 ? 69.274  -9.338  42.909 1.00 58.25  ? 448 SER D C   1 
ATOM   11262 O O   . SER D 1 246 ? 69.205  -8.364  42.154 1.00 59.54  ? 448 SER D O   1 
ATOM   11263 C CB  . SER D 1 246 ? 70.198  -9.106  45.217 1.00 59.10  ? 448 SER D CB  1 
ATOM   11264 O OG  . SER D 1 246 ? 70.933  -10.311 45.126 1.00 60.69  ? 448 SER D OG  1 
ATOM   11265 N N   . LYS D 1 247 ? 69.645  -10.541 42.475 1.00 59.32  ? 449 LYS D N   1 
ATOM   11266 C CA  . LYS D 1 247 ? 70.181  -10.743 41.133 1.00 60.95  ? 449 LYS D CA  1 
ATOM   11267 C C   . LYS D 1 247 ? 69.501  -11.927 40.470 1.00 62.00  ? 449 LYS D C   1 
ATOM   11268 O O   . LYS D 1 247 ? 69.420  -13.007 41.062 1.00 62.90  ? 449 LYS D O   1 
ATOM   11269 C CB  . LYS D 1 247 ? 71.694  -10.984 41.165 1.00 59.93  ? 449 LYS D CB  1 
ATOM   11270 C CG  . LYS D 1 247 ? 72.521  -9.795  41.598 1.00 62.30  ? 449 LYS D CG  1 
ATOM   11271 C CD  . LYS D 1 247 ? 73.995  -10.160 41.656 1.00 65.10  ? 449 LYS D CD  1 
ATOM   11272 C CE  . LYS D 1 247 ? 74.845  -8.970  42.057 1.00 67.88  ? 449 LYS D CE  1 
ATOM   11273 N NZ  . LYS D 1 247 ? 76.286  -9.331  42.174 1.00 70.64  ? 449 LYS D NZ  1 
ATOM   11274 N N   . THR D 1 248 ? 69.010  -11.725 39.248 1.00 65.07  ? 450 THR D N   1 
ATOM   11275 C CA  . THR D 1 248 ? 68.470  -12.823 38.463 1.00 66.16  ? 450 THR D CA  1 
ATOM   11276 C C   . THR D 1 248 ? 69.454  -13.387 37.444 1.00 67.41  ? 450 THR D C   1 
ATOM   11277 O O   . THR D 1 248 ? 69.146  -14.404 36.816 1.00 67.39  ? 450 THR D O   1 
ATOM   11278 C CB  . THR D 1 248 ? 67.193  -12.381 37.742 1.00 61.69  ? 450 THR D CB  1 
ATOM   11279 O OG1 . THR D 1 248 ? 67.499  -11.312 36.842 1.00 62.35  ? 450 THR D OG1 1 
ATOM   11280 C CG2 . THR D 1 248 ? 66.169  -11.902 38.752 1.00 60.87  ? 450 THR D CG2 1 
ATOM   11281 N N   . ILE D 1 249 ? 70.628  -12.773 37.278 1.00 67.57  ? 451 ILE D N   1 
ATOM   11282 C CA  . ILE D 1 249 ? 71.652  -13.257 36.358 1.00 69.36  ? 451 ILE D CA  1 
ATOM   11283 C C   . ILE D 1 249 ? 73.028  -12.943 36.924 1.00 71.02  ? 451 ILE D C   1 
ATOM   11284 O O   . ILE D 1 249 ? 73.198  -12.020 37.725 1.00 71.55  ? 451 ILE D O   1 
ATOM   11285 C CB  . ILE D 1 249 ? 71.528  -12.653 34.939 1.00 69.86  ? 451 ILE D CB  1 
ATOM   11286 C CG1 . ILE D 1 249 ? 71.519  -11.126 35.002 1.00 69.86  ? 451 ILE D CG1 1 
ATOM   11287 C CG2 . ILE D 1 249 ? 70.339  -13.218 34.192 1.00 69.86  ? 451 ILE D CG2 1 
ATOM   11288 C CD1 . ILE D 1 249 ? 71.588  -10.466 33.647 1.00 69.86  ? 451 ILE D CD1 1 
ATOM   11289 N N   . ASN D 1 250 ? 74.019  -13.723 36.488 1.00 75.13  ? 452 ASN D N   1 
ATOM   11290 C CA  . ASN D 1 250 ? 75.400  -13.470 36.883 1.00 77.50  ? 452 ASN D CA  1 
ATOM   11291 C C   . ASN D 1 250 ? 76.012  -12.330 36.078 1.00 78.98  ? 452 ASN D C   1 
ATOM   11292 O O   . ASN D 1 250 ? 76.721  -11.485 36.634 1.00 79.13  ? 452 ASN D O   1 
ATOM   11293 C CB  . ASN D 1 250 ? 76.236  -14.738 36.719 1.00 72.54  ? 452 ASN D CB  1 
ATOM   11294 C CG  . ASN D 1 250 ? 75.786  -15.856 37.634 1.00 74.74  ? 452 ASN D CG  1 
ATOM   11295 O OD1 . ASN D 1 250 ? 75.598  -16.991 37.198 1.00 76.22  ? 452 ASN D OD1 1 
ATOM   11296 N ND2 . ASN D 1 250 ? 75.618  -15.543 38.913 1.00 76.06  ? 452 ASN D ND2 1 
ATOM   11297 N N   . GLY D 1 251 ? 75.755  -12.294 34.776 1.00 79.70  ? 453 GLY D N   1 
ATOM   11298 C CA  . GLY D 1 251 ? 76.322  -11.265 33.932 1.00 82.05  ? 453 GLY D CA  1 
ATOM   11299 C C   . GLY D 1 251 ? 75.861  -11.438 32.499 1.00 84.06  ? 453 GLY D C   1 
ATOM   11300 O O   . GLY D 1 251 ? 74.858  -12.101 32.224 1.00 85.05  ? 453 GLY D O   1 
ATOM   11301 N N   . SER D 1 252 ? 76.616  -10.826 31.592 1.00 89.81  ? 454 SER D N   1 
ATOM   11302 C CA  . SER D 1 252 ? 76.292  -10.909 30.175 1.00 90.31  ? 454 SER D CA  1 
ATOM   11303 C C   . SER D 1 252 ? 76.738  -12.247 29.601 1.00 89.56  ? 454 SER D C   1 
ATOM   11304 O O   . SER D 1 252 ? 77.833  -12.736 29.894 1.00 89.04  ? 454 SER D O   1 
ATOM   11305 C CB  . SER D 1 252 ? 76.956  -9.765  29.411 1.00 88.83  ? 454 SER D CB  1 
ATOM   11306 O OG  . SER D 1 252 ? 78.367  -9.862  29.481 1.00 90.83  ? 454 SER D OG  1 
ATOM   11307 N N   . GLY D 1 253 ? 75.884  -12.841 28.783 1.00 86.29  ? 455 GLY D N   1 
ATOM   11308 C CA  . GLY D 1 253 ? 76.191  -14.104 28.151 1.00 85.70  ? 455 GLY D CA  1 
ATOM   11309 C C   . GLY D 1 253 ? 74.922  -14.892 27.897 1.00 85.54  ? 455 GLY D C   1 
ATOM   11310 O O   . GLY D 1 253 ? 73.830  -14.337 27.851 1.00 85.31  ? 455 GLY D O   1 
ATOM   11311 N N   . GLN D 1 254 ? 75.098  -16.197 27.730 1.00 80.87  ? 456 GLN D N   1 
ATOM   11312 C CA  . GLN D 1 254 ? 73.995  -17.119 27.517 1.00 81.30  ? 456 GLN D CA  1 
ATOM   11313 C C   . GLN D 1 254 ? 73.827  -18.028 28.727 1.00 79.59  ? 456 GLN D C   1 
ATOM   11314 O O   . GLN D 1 254 ? 74.804  -18.438 29.358 1.00 79.74  ? 456 GLN D O   1 
ATOM   11315 C CB  . GLN D 1 254 ? 74.227  -17.966 26.264 1.00 78.12  ? 456 GLN D CB  1 
ATOM   11316 C CG  . GLN D 1 254 ? 74.254  -17.172 24.972 1.00 83.88  ? 456 GLN D CG  1 
ATOM   11317 C CD  . GLN D 1 254 ? 72.918  -16.541 24.653 1.00 87.24  ? 456 GLN D CD  1 
ATOM   11318 O OE1 . GLN D 1 254 ? 72.707  -15.352 24.891 1.00 88.15  ? 456 GLN D OE1 1 
ATOM   11319 N NE2 . GLN D 1 254 ? 72.004  -17.335 24.110 1.00 88.39  ? 456 GLN D NE2 1 
ATOM   11320 N N   . ASN D 1 255 ? 72.568  -18.333 29.044 1.00 77.92  ? 457 ASN D N   1 
ATOM   11321 C CA  . ASN D 1 255 ? 72.223  -19.251 30.131 1.00 76.18  ? 457 ASN D CA  1 
ATOM   11322 C C   . ASN D 1 255 ? 72.805  -18.782 31.463 1.00 74.24  ? 457 ASN D C   1 
ATOM   11323 O O   . ASN D 1 255 ? 73.343  -19.571 32.241 1.00 73.33  ? 457 ASN D O   1 
ATOM   11324 C CB  . ASN D 1 255 ? 72.677  -20.676 29.811 1.00 74.87  ? 457 ASN D CB  1 
ATOM   11325 C CG  . ASN D 1 255 ? 71.909  -21.283 28.661 1.00 76.15  ? 457 ASN D CG  1 
ATOM   11326 O OD1 . ASN D 1 255 ? 70.796  -20.861 28.353 1.00 76.95  ? 457 ASN D OD1 1 
ATOM   11327 N ND2 . ASN D 1 255 ? 72.499  -22.284 28.018 1.00 76.89  ? 457 ASN D ND2 1 
ATOM   11328 N N   . GLN D 1 256 ? 72.687  -17.489 31.732 1.00 74.58  ? 458 GLN D N   1 
ATOM   11329 C CA  . GLN D 1 256 ? 73.219  -16.921 32.962 1.00 72.82  ? 458 GLN D CA  1 
ATOM   11330 C C   . GLN D 1 256 ? 72.160  -16.736 34.042 1.00 70.99  ? 458 GLN D C   1 
ATOM   11331 O O   . GLN D 1 256 ? 72.420  -16.109 35.062 1.00 70.91  ? 458 GLN D O   1 
ATOM   11332 C CB  . GLN D 1 256 ? 73.885  -15.580 32.666 1.00 76.74  ? 458 GLN D CB  1 
ATOM   11333 C CG  . GLN D 1 256 ? 74.864  -15.622 31.508 1.00 79.34  ? 458 GLN D CG  1 
ATOM   11334 C CD  . GLN D 1 256 ? 76.270  -15.964 31.948 1.00 81.73  ? 458 GLN D CD  1 
ATOM   11335 O OE1 . GLN D 1 256 ? 76.836  -15.306 32.820 1.00 82.92  ? 458 GLN D OE1 1 
ATOM   11336 N NE2 . GLN D 1 256 ? 76.845  -16.992 31.341 1.00 83.06  ? 458 GLN D NE2 1 
ATOM   11337 N N   . GLN D 1 257 ? 70.976  -17.302 33.840 1.00 70.24  ? 459 GLN D N   1 
ATOM   11338 C CA  . GLN D 1 257 ? 69.914  -17.137 34.822 1.00 68.33  ? 459 GLN D CA  1 
ATOM   11339 C C   . GLN D 1 257 ? 70.308  -17.732 36.164 1.00 67.53  ? 459 GLN D C   1 
ATOM   11340 O O   . GLN D 1 257 ? 70.871  -18.822 36.235 1.00 67.80  ? 459 GLN D O   1 
ATOM   11341 C CB  . GLN D 1 257 ? 68.614  -17.790 34.345 1.00 68.79  ? 459 GLN D CB  1 
ATOM   11342 C CG  . GLN D 1 257 ? 68.179  -17.407 32.944 1.00 69.64  ? 459 GLN D CG  1 
ATOM   11343 C CD  . GLN D 1 257 ? 68.668  -18.384 31.900 1.00 69.01  ? 459 GLN D CD  1 
ATOM   11344 O OE1 . GLN D 1 257 ? 69.292  -19.392 32.223 1.00 69.04  ? 459 GLN D OE1 1 
ATOM   11345 N NE2 . GLN D 1 257 ? 68.382  -18.095 30.640 1.00 67.96  ? 459 GLN D NE2 1 
ATOM   11346 N N   . THR D 1 258 ? 70.014  -16.997 37.229 1.00 66.65  ? 460 THR D N   1 
ATOM   11347 C CA  . THR D 1 258 ? 70.316  -17.441 38.579 1.00 66.55  ? 460 THR D CA  1 
ATOM   11348 C C   . THR D 1 258 ? 69.449  -16.704 39.589 1.00 64.69  ? 460 THR D C   1 
ATOM   11349 O O   . THR D 1 258 ? 68.846  -15.685 39.266 1.00 65.04  ? 460 THR D O   1 
ATOM   11350 C CB  . THR D 1 258 ? 71.795  -17.221 38.928 1.00 67.01  ? 460 THR D CB  1 
ATOM   11351 O OG1 . THR D 1 258 ? 72.113  -17.940 40.125 1.00 66.64  ? 460 THR D OG1 1 
ATOM   11352 C CG2 . THR D 1 258 ? 72.079  -15.748 39.136 1.00 69.14  ? 460 THR D CG2 1 
ATOM   11353 N N   . LEU D 1 259 ? 69.367  -17.238 40.801 1.00 64.90  ? 461 LEU D N   1 
ATOM   11354 C CA  . LEU D 1 259 ? 68.610  -16.601 41.867 1.00 62.10  ? 461 LEU D CA  1 
ATOM   11355 C C   . LEU D 1 259 ? 69.562  -16.288 43.011 1.00 62.24  ? 461 LEU D C   1 
ATOM   11356 O O   . LEU D 1 259 ? 70.259  -17.171 43.496 1.00 63.53  ? 461 LEU D O   1 
ATOM   11357 C CB  . LEU D 1 259 ? 67.505  -17.530 42.363 1.00 63.89  ? 461 LEU D CB  1 
ATOM   11358 C CG  . LEU D 1 259 ? 66.085  -17.397 41.810 1.00 61.75  ? 461 LEU D CG  1 
ATOM   11359 C CD1 . LEU D 1 259 ? 66.032  -16.678 40.473 1.00 60.03  ? 461 LEU D CD1 1 
ATOM   11360 C CD2 . LEU D 1 259 ? 65.431  -18.765 41.726 1.00 59.95  ? 461 LEU D CD2 1 
ATOM   11361 N N   . LYS D 1 260 ? 69.591  -15.034 43.445 1.00 58.77  ? 462 LYS D N   1 
ATOM   11362 C CA  . LYS D 1 260 ? 70.457  -14.620 44.542 1.00 58.20  ? 462 LYS D CA  1 
ATOM   11363 C C   . LYS D 1 260 ? 69.663  -13.783 45.534 1.00 57.25  ? 462 LYS D C   1 
ATOM   11364 O O   . LYS D 1 260 ? 68.759  -13.049 45.147 1.00 56.77  ? 462 LYS D O   1 
ATOM   11365 C CB  . LYS D 1 260 ? 71.642  -13.811 44.019 1.00 57.73  ? 462 LYS D CB  1 
ATOM   11366 C CG  . LYS D 1 260 ? 72.456  -14.507 42.945 1.00 59.50  ? 462 LYS D CG  1 
ATOM   11367 C CD  . LYS D 1 260 ? 73.266  -15.653 43.517 1.00 60.30  ? 462 LYS D CD  1 
ATOM   11368 C CE  . LYS D 1 260 ? 74.258  -16.171 42.492 1.00 62.46  ? 462 LYS D CE  1 
ATOM   11369 N NZ  . LYS D 1 260 ? 75.306  -17.024 43.112 1.00 64.13  ? 462 LYS D NZ  1 
ATOM   11370 N N   . PHE D 1 261 ? 70.000  -13.889 46.813 1.00 55.28  ? 463 PHE D N   1 
ATOM   11371 C CA  . PHE D 1 261 ? 69.293  -13.137 47.841 1.00 53.91  ? 463 PHE D CA  1 
ATOM   11372 C C   . PHE D 1 261 ? 70.227  -12.318 48.728 1.00 53.67  ? 463 PHE D C   1 
ATOM   11373 O O   . PHE D 1 261 ? 71.305  -12.772 49.086 1.00 54.01  ? 463 PHE D O   1 
ATOM   11374 C CB  . PHE D 1 261 ? 68.433  -14.079 48.683 1.00 56.89  ? 463 PHE D CB  1 
ATOM   11375 C CG  . PHE D 1 261 ? 67.372  -14.788 47.894 1.00 55.37  ? 463 PHE D CG  1 
ATOM   11376 C CD1 . PHE D 1 261 ? 66.087  -14.280 47.825 1.00 54.45  ? 463 PHE D CD1 1 
ATOM   11377 C CD2 . PHE D 1 261 ? 67.661  -15.956 47.213 1.00 55.14  ? 463 PHE D CD2 1 
ATOM   11378 C CE1 . PHE D 1 261 ? 65.113  -14.923 47.094 1.00 53.35  ? 463 PHE D CE1 1 
ATOM   11379 C CE2 . PHE D 1 261 ? 66.690  -16.604 46.479 1.00 54.24  ? 463 PHE D CE2 1 
ATOM   11380 C CZ  . PHE D 1 261 ? 65.415  -16.086 46.419 1.00 53.38  ? 463 PHE D CZ  1 
ATOM   11381 N N   . SER D 1 262 ? 69.807  -11.103 49.062 1.00 51.16  ? 464 SER D N   1 
ATOM   11382 C CA  . SER D 1 262 ? 70.593  -10.215 49.912 1.00 51.66  ? 464 SER D CA  1 
ATOM   11383 C C   . SER D 1 262 ? 69.742  -9.636  51.036 1.00 51.80  ? 464 SER D C   1 
ATOM   11384 O O   . SER D 1 262 ? 68.522  -9.557  50.932 1.00 51.71  ? 464 SER D O   1 
ATOM   11385 C CB  . SER D 1 262 ? 71.221  -9.098  49.089 1.00 53.12  ? 464 SER D CB  1 
ATOM   11386 O OG  . SER D 1 262 ? 72.025  -9.636  48.061 1.00 53.37  ? 464 SER D OG  1 
ATOM   11387 N N   . VAL D 1 263 ? 70.403  -9.208  52.102 1.00 52.08  ? 465 VAL D N   1 
ATOM   11388 C CA  . VAL D 1 263 ? 69.714  -8.686  53.275 1.00 53.32  ? 465 VAL D CA  1 
ATOM   11389 C C   . VAL D 1 263 ? 69.138  -7.314  52.960 1.00 54.00  ? 465 VAL D C   1 
ATOM   11390 O O   . VAL D 1 263 ? 69.788  -6.480  52.320 1.00 54.29  ? 465 VAL D O   1 
ATOM   11391 C CB  . VAL D 1 263 ? 70.678  -8.615  54.473 1.00 49.87  ? 465 VAL D CB  1 
ATOM   11392 C CG1 . VAL D 1 263 ? 69.973  -8.056  55.695 1.00 50.12  ? 465 VAL D CG1 1 
ATOM   11393 C CG2 . VAL D 1 263 ? 71.271  -9.976  54.764 1.00 50.48  ? 465 VAL D CG2 1 
ATOM   11394 N N   . ALA D 1 264 ? 67.911  -7.074  53.413 1.00 50.89  ? 466 ALA D N   1 
ATOM   11395 C CA  . ALA D 1 264 ? 67.337  -5.738  53.359 1.00 52.11  ? 466 ALA D CA  1 
ATOM   11396 C C   . ALA D 1 264 ? 67.870  -4.922  54.529 1.00 53.58  ? 466 ALA D C   1 
ATOM   11397 O O   . ALA D 1 264 ? 67.689  -5.296  55.692 1.00 54.04  ? 466 ALA D O   1 
ATOM   11398 C CB  . ALA D 1 264 ? 65.812  -5.803  53.398 1.00 48.33  ? 466 ALA D CB  1 
ATOM   11399 N N   . GLY D 1 265 ? 68.524  -3.807  54.221 1.00 55.42  ? 467 GLY D N   1 
ATOM   11400 C CA  . GLY D 1 265 ? 69.230  -3.045  55.221 1.00 56.26  ? 467 GLY D CA  1 
ATOM   11401 C C   . GLY D 1 265 ? 69.316  -1.573  54.882 1.00 56.52  ? 467 GLY D C   1 
ATOM   11402 O O   . GLY D 1 265 ? 68.729  -1.100  53.905 1.00 56.27  ? 467 GLY D O   1 
ATOM   11403 N N   . PRO D 1 266 ? 70.041  -0.815  55.706 1.00 57.40  ? 468 PRO D N   1 
ATOM   11404 C CA  . PRO D 1 266 ? 70.124  0.639   55.494 1.00 57.79  ? 468 PRO D CA  1 
ATOM   11405 C C   . PRO D 1 266 ? 70.654  1.038   54.131 1.00 58.39  ? 468 PRO D C   1 
ATOM   11406 O O   . PRO D 1 266 ? 70.309  2.119   53.638 1.00 58.26  ? 468 PRO D O   1 
ATOM   11407 C CB  . PRO D 1 266 ? 71.071  1.092   56.614 1.00 56.44  ? 468 PRO D CB  1 
ATOM   11408 C CG  . PRO D 1 266 ? 70.925  0.051   57.668 1.00 56.36  ? 468 PRO D CG  1 
ATOM   11409 C CD  . PRO D 1 266 ? 70.753  -1.236  56.923 1.00 56.73  ? 468 PRO D CD  1 
ATOM   11410 N N   . SER D 1 267 ? 71.488  0.204   53.505 1.00 59.97  ? 469 SER D N   1 
ATOM   11411 C CA  . SER D 1 267 ? 72.090  0.582   52.231 1.00 60.75  ? 469 SER D CA  1 
ATOM   11412 C C   . SER D 1 267 ? 71.043  0.766   51.141 1.00 60.71  ? 469 SER D C   1 
ATOM   11413 O O   . SER D 1 267 ? 71.071  1.772   50.424 1.00 60.91  ? 469 SER D O   1 
ATOM   11414 C CB  . SER D 1 267 ? 73.124  -0.463  51.811 1.00 60.64  ? 469 SER D CB  1 
ATOM   11415 O OG  . SER D 1 267 ? 72.522  -1.728  51.603 1.00 65.18  ? 469 SER D OG  1 
ATOM   11416 N N   . ASN D 1 268 ? 70.120  -0.182  51.001 1.00 59.93  ? 470 ASN D N   1 
ATOM   11417 C CA  . ASN D 1 268 ? 69.008  -0.078  50.058 1.00 58.65  ? 470 ASN D CA  1 
ATOM   11418 C C   . ASN D 1 268 ? 67.715  -0.139  50.863 1.00 57.19  ? 470 ASN D C   1 
ATOM   11419 O O   . ASN D 1 268 ? 67.362  -1.191  51.404 1.00 56.06  ? 470 ASN D O   1 
ATOM   11420 C CB  . ASN D 1 268 ? 69.071  -1.188  49.014 1.00 57.22  ? 470 ASN D CB  1 
ATOM   11421 C CG  . ASN D 1 268 ? 68.092  -0.976  47.883 1.00 59.86  ? 470 ASN D CG  1 
ATOM   11422 O OD1 . ASN D 1 268 ? 67.759  0.157   47.540 1.00 60.70  ? 470 ASN D OD1 1 
ATOM   11423 N ND2 . ASN D 1 268 ? 67.627  -2.068  47.293 1.00 60.69  ? 470 ASN D ND2 1 
ATOM   11424 N N   . MET D 1 269 ? 67.008  0.985   50.936 1.00 54.93  ? 471 MET D N   1 
ATOM   11425 C CA  . MET D 1 269 ? 65.793  1.080   51.731 1.00 54.71  ? 471 MET D CA  1 
ATOM   11426 C C   . MET D 1 269 ? 64.521  0.889   50.919 1.00 53.51  ? 471 MET D C   1 
ATOM   11427 O O   . MET D 1 269 ? 63.430  0.912   51.495 1.00 54.18  ? 471 MET D O   1 
ATOM   11428 C CB  . MET D 1 269 ? 65.736  2.435   52.441 1.00 54.28  ? 471 MET D CB  1 
ATOM   11429 C CG  . MET D 1 269 ? 66.829  2.636   53.470 1.00 57.03  ? 471 MET D CG  1 
ATOM   11430 S SD  . MET D 1 269 ? 66.727  4.242   54.273 1.00 58.93  ? 471 MET D SD  1 
ATOM   11431 C CE  . MET D 1 269 ? 68.126  4.151   55.383 1.00 59.08  ? 471 MET D CE  1 
ATOM   11432 N N   . ALA D 1 270 ? 64.630  0.709   49.603 1.00 55.13  ? 472 ALA D N   1 
ATOM   11433 C CA  . ALA D 1 270 ? 63.434  0.582   48.779 1.00 53.42  ? 472 ALA D CA  1 
ATOM   11434 C C   . ALA D 1 270 ? 62.841  -0.819  48.845 1.00 52.48  ? 472 ALA D C   1 
ATOM   11435 O O   . ALA D 1 270 ? 61.625  -0.982  48.696 1.00 52.32  ? 472 ALA D O   1 
ATOM   11436 C CB  . ALA D 1 270 ? 63.756  0.950   47.332 1.00 51.47  ? 472 ALA D CB  1 
ATOM   11437 N N   . VAL D 1 271 ? 63.674  -1.838  49.064 1.00 52.69  ? 473 VAL D N   1 
ATOM   11438 C CA  . VAL D 1 271 ? 63.246  -3.226  48.954 1.00 51.54  ? 473 VAL D CA  1 
ATOM   11439 C C   . VAL D 1 271 ? 62.858  -3.840  50.289 1.00 50.03  ? 473 VAL D C   1 
ATOM   11440 O O   . VAL D 1 271 ? 62.566  -5.042  50.340 1.00 49.53  ? 473 VAL D O   1 
ATOM   11441 C CB  . VAL D 1 271 ? 64.336  -4.081  48.283 1.00 50.97  ? 473 VAL D CB  1 
ATOM   11442 C CG1 . VAL D 1 271 ? 64.565  -3.617  46.861 1.00 55.32  ? 473 VAL D CG1 1 
ATOM   11443 C CG2 . VAL D 1 271 ? 65.618  -4.002  49.082 1.00 51.57  ? 473 VAL D CG2 1 
ATOM   11444 N N   . GLN D 1 272 ? 62.858  -3.070  51.372 1.00 49.07  ? 474 GLN D N   1 
ATOM   11445 C CA  . GLN D 1 272 ? 62.557  -3.645  52.674 1.00 47.64  ? 474 GLN D CA  1 
ATOM   11446 C C   . GLN D 1 272 ? 61.083  -4.017  52.786 1.00 47.18  ? 474 GLN D C   1 
ATOM   11447 O O   . GLN D 1 272 ? 60.206  -3.364  52.216 1.00 47.68  ? 474 GLN D O   1 
ATOM   11448 C CB  . GLN D 1 272 ? 62.912  -2.678  53.797 1.00 48.56  ? 474 GLN D CB  1 
ATOM   11449 C CG  . GLN D 1 272 ? 64.379  -2.347  53.915 1.00 51.60  ? 474 GLN D CG  1 
ATOM   11450 C CD  . GLN D 1 272 ? 64.649  -1.476  55.117 1.00 53.23  ? 474 GLN D CD  1 
ATOM   11451 O OE1 . GLN D 1 272 ? 63.734  -0.861  55.659 1.00 54.47  ? 474 GLN D OE1 1 
ATOM   11452 N NE2 . GLN D 1 272 ? 65.905  -1.406  55.533 1.00 54.91  ? 474 GLN D NE2 1 
ATOM   11453 N N   . GLY D 1 273 ? 60.818  -5.080  53.539 1.00 48.01  ? 475 GLY D N   1 
ATOM   11454 C CA  . GLY D 1 273 ? 59.444  -5.465  53.803 1.00 46.87  ? 475 GLY D CA  1 
ATOM   11455 C C   . GLY D 1 273 ? 58.774  -4.495  54.760 1.00 47.63  ? 475 GLY D C   1 
ATOM   11456 O O   . GLY D 1 273 ? 59.310  -4.159  55.817 1.00 48.08  ? 475 GLY D O   1 
ATOM   11457 N N   . ARG D 1 274 ? 57.580  -4.046  54.383 1.00 41.12  ? 476 ARG D N   1 
ATOM   11458 C CA  . ARG D 1 274 ? 56.839  -3.064  55.157 1.00 40.87  ? 476 ARG D CA  1 
ATOM   11459 C C   . ARG D 1 274 ? 55.445  -3.586  55.471 1.00 40.61  ? 476 ARG D C   1 
ATOM   11460 O O   . ARG D 1 274 ? 54.853  -4.338  54.693 1.00 41.70  ? 476 ARG D O   1 
ATOM   11461 C CB  . ARG D 1 274 ? 56.741  -1.729  54.415 1.00 41.61  ? 476 ARG D CB  1 
ATOM   11462 C CG  . ARG D 1 274 ? 58.070  -1.013  54.258 1.00 43.16  ? 476 ARG D CG  1 
ATOM   11463 C CD  . ARG D 1 274 ? 57.904  0.283   53.486 1.00 44.51  ? 476 ARG D CD  1 
ATOM   11464 N NE  . ARG D 1 274 ? 59.153  1.031   53.379 1.00 48.74  ? 476 ARG D NE  1 
ATOM   11465 C CZ  . ARG D 1 274 ? 60.079  0.816   52.452 1.00 49.61  ? 476 ARG D CZ  1 
ATOM   11466 N NH1 . ARG D 1 274 ? 59.906  -0.131  51.543 1.00 52.42  ? 476 ARG D NH1 1 
ATOM   11467 N NH2 . ARG D 1 274 ? 61.181  1.551   52.433 1.00 51.71  ? 476 ARG D NH2 1 
ATOM   11468 N N   . ASN D 1 275 ? 54.929  -3.172  56.625 1.00 40.73  ? 477 ASN D N   1 
ATOM   11469 C CA  . ASN D 1 275 ? 53.620  -3.594  57.102 1.00 40.10  ? 477 ASN D CA  1 
ATOM   11470 C C   . ASN D 1 275 ? 52.463  -2.848  56.456 1.00 39.74  ? 477 ASN D C   1 
ATOM   11471 O O   . ASN D 1 275 ? 51.386  -3.430  56.306 1.00 38.76  ? 477 ASN D O   1 
ATOM   11472 C CB  . ASN D 1 275 ? 53.537  -3.422  58.621 1.00 39.24  ? 477 ASN D CB  1 
ATOM   11473 C CG  . ASN D 1 275 ? 54.312  -4.480  59.365 1.00 40.76  ? 477 ASN D CG  1 
ATOM   11474 O OD1 . ASN D 1 275 ? 54.469  -5.596  58.882 1.00 43.08  ? 477 ASN D OD1 1 
ATOM   11475 N ND2 . ASN D 1 275 ? 54.819  -4.129  60.538 1.00 41.10  ? 477 ASN D ND2 1 
ATOM   11476 N N   . TYR D 1 276 ? 52.642  -1.585  56.083 1.00 36.03  ? 478 TYR D N   1 
ATOM   11477 C CA  . TYR D 1 276 ? 51.525  -0.794  55.593 1.00 37.09  ? 478 TYR D CA  1 
ATOM   11478 C C   . TYR D 1 276 ? 51.897  -0.138  54.273 1.00 38.17  ? 478 TYR D C   1 
ATOM   11479 O O   . TYR D 1 276 ? 53.061  0.187   54.030 1.00 40.30  ? 478 TYR D O   1 
ATOM   11480 C CB  . TYR D 1 276 ? 51.103  0.264   56.617 1.00 36.32  ? 478 TYR D CB  1 
ATOM   11481 C CG  . TYR D 1 276 ? 50.595  -0.323  57.913 1.00 38.53  ? 478 TYR D CG  1 
ATOM   11482 C CD1 . TYR D 1 276 ? 49.265  -0.688  58.055 1.00 39.03  ? 478 TYR D CD1 1 
ATOM   11483 C CD2 . TYR D 1 276 ? 51.445  -0.515  58.992 1.00 37.72  ? 478 TYR D CD2 1 
ATOM   11484 C CE1 . TYR D 1 276 ? 48.796  -1.226  59.232 1.00 39.27  ? 478 TYR D CE1 1 
ATOM   11485 C CE2 . TYR D 1 276 ? 50.984  -1.053  60.174 1.00 39.57  ? 478 TYR D CE2 1 
ATOM   11486 C CZ  . TYR D 1 276 ? 49.659  -1.407  60.288 1.00 40.39  ? 478 TYR D CZ  1 
ATOM   11487 O OH  . TYR D 1 276 ? 49.194  -1.943  61.464 1.00 41.94  ? 478 TYR D OH  1 
ATOM   11488 N N   . ILE D 1 277 ? 50.890  0.051   53.426 1.00 35.30  ? 479 ILE D N   1 
ATOM   11489 C CA  . ILE D 1 277 ? 51.079  0.623   52.095 1.00 34.69  ? 479 ILE D CA  1 
ATOM   11490 C C   . ILE D 1 277 ? 50.247  1.895   52.000 1.00 35.85  ? 479 ILE D C   1 
ATOM   11491 O O   . ILE D 1 277 ? 49.297  2.088   52.774 1.00 36.22  ? 479 ILE D O   1 
ATOM   11492 C CB  . ILE D 1 277 ? 50.697  -0.383  50.984 1.00 36.93  ? 479 ILE D CB  1 
ATOM   11493 C CG1 . ILE D 1 277 ? 49.229  -0.786  51.106 1.00 35.30  ? 479 ILE D CG1 1 
ATOM   11494 C CG2 . ILE D 1 277 ? 51.593  -1.603  51.045 1.00 35.75  ? 479 ILE D CG2 1 
ATOM   11495 C CD1 . ILE D 1 277 ? 48.735  -1.628  49.955 1.00 33.81  ? 479 ILE D CD1 1 
ATOM   11496 N N   . PRO D 1 278 ? 50.588  2.793   51.076 1.00 37.55  ? 480 PRO D N   1 
ATOM   11497 C CA  . PRO D 1 278 ? 49.843  4.049   50.968 1.00 37.99  ? 480 PRO D CA  1 
ATOM   11498 C C   . PRO D 1 278 ? 48.404  3.828   50.528 1.00 38.67  ? 480 PRO D C   1 
ATOM   11499 O O   . PRO D 1 278 ? 48.038  2.791   49.973 1.00 38.15  ? 480 PRO D O   1 
ATOM   11500 C CB  . PRO D 1 278 ? 50.631  4.838   49.919 1.00 39.18  ? 480 PRO D CB  1 
ATOM   11501 C CG  . PRO D 1 278 ? 51.315  3.798   49.117 1.00 39.63  ? 480 PRO D CG  1 
ATOM   11502 C CD  . PRO D 1 278 ? 51.692  2.742   50.104 1.00 38.41  ? 480 PRO D CD  1 
ATOM   11503 N N   . GLY D 1 279 ? 47.588  4.850   50.772 1.00 37.28  ? 481 GLY D N   1 
ATOM   11504 C CA  . GLY D 1 279 ? 46.165  4.777   50.544 1.00 38.35  ? 481 GLY D CA  1 
ATOM   11505 C C   . GLY D 1 279 ? 45.784  4.740   49.080 1.00 39.22  ? 481 GLY D C   1 
ATOM   11506 O O   . GLY D 1 279 ? 46.633  4.649   48.190 1.00 39.77  ? 481 GLY D O   1 
ATOM   11507 N N   . PRO D 1 280 ? 44.487  4.816   48.805 1.00 37.19  ? 482 PRO D N   1 
ATOM   11508 C CA  . PRO D 1 280 ? 44.005  4.679   47.430 1.00 37.74  ? 482 PRO D CA  1 
ATOM   11509 C C   . PRO D 1 280 ? 44.408  5.862   46.564 1.00 38.74  ? 482 PRO D C   1 
ATOM   11510 O O   . PRO D 1 280 ? 44.783  6.929   47.051 1.00 38.84  ? 482 PRO D O   1 
ATOM   11511 C CB  . PRO D 1 280 ? 42.485  4.619   47.600 1.00 35.10  ? 482 PRO D CB  1 
ATOM   11512 C CG  . PRO D 1 280 ? 42.234  5.389   48.841 1.00 34.97  ? 482 PRO D CG  1 
ATOM   11513 C CD  . PRO D 1 280 ? 43.392  5.093   49.748 1.00 34.66  ? 482 PRO D CD  1 
ATOM   11514 N N   . SER D 1 281 ? 44.322  5.652   45.253 1.00 38.01  ? 483 SER D N   1 
ATOM   11515 C CA  . SER D 1 281 ? 44.686  6.678   44.289 1.00 38.87  ? 483 SER D CA  1 
ATOM   11516 C C   . SER D 1 281 ? 43.748  6.628   43.095 1.00 38.29  ? 483 SER D C   1 
ATOM   11517 O O   . SER D 1 281 ? 43.335  5.555   42.655 1.00 38.73  ? 483 SER D O   1 
ATOM   11518 C CB  . SER D 1 281 ? 46.123  6.512   43.794 1.00 37.15  ? 483 SER D CB  1 
ATOM   11519 O OG  . SER D 1 281 ? 46.244  5.324   43.036 1.00 39.59  ? 483 SER D OG  1 
ATOM   11520 N N   . TYR D 1 282 ? 43.396  7.808   42.593 1.00 39.35  ? 484 TYR D N   1 
ATOM   11521 C CA  . TYR D 1 282 ? 42.676  7.950   41.331 1.00 37.38  ? 484 TYR D CA  1 
ATOM   11522 C C   . TYR D 1 282 ? 43.366  9.095   40.597 1.00 36.80  ? 484 TYR D C   1 
ATOM   11523 O O   . TYR D 1 282 ? 43.235  10.246  41.018 1.00 37.07  ? 484 TYR D O   1 
ATOM   11524 C CB  . TYR D 1 282 ? 41.205  8.253   41.619 1.00 32.25  ? 484 TYR D CB  1 
ATOM   11525 C CG  . TYR D 1 282 ? 40.229  8.173   40.472 1.00 31.19  ? 484 TYR D CG  1 
ATOM   11526 C CD1 . TYR D 1 282 ? 39.692  6.956   40.083 1.00 31.05  ? 484 TYR D CD1 1 
ATOM   11527 C CD2 . TYR D 1 282 ? 39.809  9.312   39.810 1.00 30.51  ? 484 TYR D CD2 1 
ATOM   11528 C CE1 . TYR D 1 282 ? 38.780  6.873   39.058 1.00 30.15  ? 484 TYR D CE1 1 
ATOM   11529 C CE2 . TYR D 1 282 ? 38.901  9.238   38.779 1.00 29.60  ? 484 TYR D CE2 1 
ATOM   11530 C CZ  . TYR D 1 282 ? 38.391  8.017   38.406 1.00 30.10  ? 484 TYR D CZ  1 
ATOM   11531 O OH  . TYR D 1 282 ? 37.484  7.943   37.378 1.00 29.79  ? 484 TYR D OH  1 
ATOM   11532 N N   . ARG D 1 283 ? 44.067  8.815   39.497 1.00 40.08  ? 485 ARG D N   1 
ATOM   11533 C CA  . ARG D 1 283 ? 45.015  9.806   38.992 1.00 39.57  ? 485 ARG D CA  1 
ATOM   11534 C C   . ARG D 1 283 ? 44.298  11.023  38.420 1.00 39.65  ? 485 ARG D C   1 
ATOM   11535 O O   . ARG D 1 283 ? 43.250  10.908  37.779 1.00 39.24  ? 485 ARG D O   1 
ATOM   11536 C CB  . ARG D 1 283 ? 45.946  9.231   37.918 1.00 43.83  ? 485 ARG D CB  1 
ATOM   11537 C CG  . ARG D 1 283 ? 46.976  10.295  37.495 1.00 45.43  ? 485 ARG D CG  1 
ATOM   11538 C CD  . ARG D 1 283 ? 47.876  10.001  36.307 1.00 44.87  ? 485 ARG D CD  1 
ATOM   11539 N NE  . ARG D 1 283 ? 48.875  8.968   36.536 1.00 45.54  ? 485 ARG D NE  1 
ATOM   11540 C CZ  . ARG D 1 283 ? 49.795  8.630   35.639 1.00 44.97  ? 485 ARG D CZ  1 
ATOM   11541 N NH1 . ARG D 1 283 ? 49.844  9.261   34.476 1.00 43.98  ? 485 ARG D NH1 1 
ATOM   11542 N NH2 . ARG D 1 283 ? 50.676  7.679   35.906 1.00 47.18  ? 485 ARG D NH2 1 
ATOM   11543 N N   . GLN D 1 284 ? 44.883  12.195  38.653 1.00 42.17  ? 486 GLN D N   1 
ATOM   11544 C CA  . GLN D 1 284 ? 44.437  13.455  38.081 1.00 42.72  ? 486 GLN D CA  1 
ATOM   11545 C C   . GLN D 1 284 ? 45.451  13.944  37.054 1.00 43.52  ? 486 GLN D C   1 
ATOM   11546 O O   . GLN D 1 284 ? 46.644  13.642  37.138 1.00 43.14  ? 486 GLN D O   1 
ATOM   11547 C CB  . GLN D 1 284 ? 44.263  14.516  39.168 1.00 37.85  ? 486 GLN D CB  1 
ATOM   11548 C CG  . GLN D 1 284 ? 43.196  14.212  40.200 1.00 39.73  ? 486 GLN D CG  1 
ATOM   11549 C CD  . GLN D 1 284 ? 41.816  14.111  39.603 1.00 41.59  ? 486 GLN D CD  1 
ATOM   11550 O OE1 . GLN D 1 284 ? 41.470  14.854  38.689 1.00 42.79  ? 486 GLN D OE1 1 
ATOM   11551 N NE2 . GLN D 1 284 ? 41.011  13.196  40.125 1.00 42.47  ? 486 GLN D NE2 1 
ATOM   11552 N N   . GLN D 1 285 ? 44.965  14.699  36.075 1.00 46.56  ? 487 GLN D N   1 
ATOM   11553 C CA  . GLN D 1 285 ? 45.848  15.305  35.090 1.00 46.62  ? 487 GLN D CA  1 
ATOM   11554 C C   . GLN D 1 285 ? 46.618  16.471  35.702 1.00 47.05  ? 487 GLN D C   1 
ATOM   11555 O O   . GLN D 1 285 ? 46.096  17.227  36.525 1.00 47.14  ? 487 GLN D O   1 
ATOM   11556 C CB  . GLN D 1 285 ? 45.045  15.776  33.880 1.00 47.10  ? 487 GLN D CB  1 
ATOM   11557 C CG  . GLN D 1 285 ? 45.883  16.385  32.785 1.00 47.01  ? 487 GLN D CG  1 
ATOM   11558 C CD  . GLN D 1 285 ? 46.892  15.412  32.239 1.00 47.54  ? 487 GLN D CD  1 
ATOM   11559 O OE1 . GLN D 1 285 ? 48.078  15.498  32.546 1.00 44.88  ? 487 GLN D OE1 1 
ATOM   11560 N NE2 . GLN D 1 285 ? 46.427  14.463  31.441 1.00 47.71  ? 487 GLN D NE2 1 
ATOM   11561 N N   . ARG D 1 286 ? 47.874  16.612  35.291 1.00 48.79  ? 488 ARG D N   1 
ATOM   11562 C CA  . ARG D 1 286 ? 48.778  17.601  35.860 1.00 48.74  ? 488 ARG D CA  1 
ATOM   11563 C C   . ARG D 1 286 ? 48.810  18.839  34.976 1.00 48.68  ? 488 ARG D C   1 
ATOM   11564 O O   . ARG D 1 286 ? 49.005  18.735  33.762 1.00 50.35  ? 488 ARG D O   1 
ATOM   11565 C CB  . ARG D 1 286 ? 50.186  17.029  36.008 1.00 48.04  ? 488 ARG D CB  1 
ATOM   11566 C CG  . ARG D 1 286 ? 51.130  17.936  36.761 1.00 49.14  ? 488 ARG D CG  1 
ATOM   11567 C CD  . ARG D 1 286 ? 52.530  17.367  36.813 1.00 51.46  ? 488 ARG D CD  1 
ATOM   11568 N NE  . ARG D 1 286 ? 53.175  17.367  35.504 1.00 54.60  ? 488 ARG D NE  1 
ATOM   11569 C CZ  . ARG D 1 286 ? 54.274  16.679  35.214 1.00 57.27  ? 488 ARG D CZ  1 
ATOM   11570 N NH1 . ARG D 1 286 ? 54.795  16.739  33.998 1.00 55.13  ? 488 ARG D NH1 1 
ATOM   11571 N NH2 . ARG D 1 286 ? 54.852  15.929  36.142 1.00 60.45  ? 488 ARG D NH2 1 
ATOM   11572 N N   . VAL D 1 287 ? 48.626  20.005  35.587 1.00 51.37  ? 489 VAL D N   1 
ATOM   11573 C CA  . VAL D 1 287 ? 48.617  21.279  34.881 1.00 50.96  ? 489 VAL D CA  1 
ATOM   11574 C C   . VAL D 1 287 ? 49.698  22.168  35.479 1.00 51.48  ? 489 VAL D C   1 
ATOM   11575 O O   . VAL D 1 287 ? 49.880  22.202  36.701 1.00 52.52  ? 489 VAL D O   1 
ATOM   11576 C CB  . VAL D 1 287 ? 47.236  21.964  34.961 1.00 48.08  ? 489 VAL D CB  1 
ATOM   11577 C CG1 . VAL D 1 287 ? 47.264  23.311  34.272 1.00 47.01  ? 489 VAL D CG1 1 
ATOM   11578 C CG2 . VAL D 1 287 ? 46.172  21.081  34.343 1.00 48.92  ? 489 VAL D CG2 1 
ATOM   11579 N N   . SER D 1 288 ? 50.421  22.878  34.617 1.00 52.01  ? 490 SER D N   1 
ATOM   11580 C CA  . SER D 1 288 ? 51.483  23.783  35.032 1.00 52.46  ? 490 SER D CA  1 
ATOM   11581 C C   . SER D 1 288 ? 50.954  25.204  35.146 1.00 53.36  ? 490 SER D C   1 
ATOM   11582 O O   . SER D 1 288 ? 50.102  25.625  34.359 1.00 51.94  ? 490 SER D O   1 
ATOM   11583 C CB  . SER D 1 288 ? 52.644  23.752  34.040 1.00 53.37  ? 490 SER D CB  1 
ATOM   11584 O OG  . SER D 1 288 ? 53.645  24.684  34.404 1.00 53.44  ? 490 SER D OG  1 
ATOM   11585 N N   . THR D 1 289 ? 51.462  25.943  36.135 1.00 51.59  ? 491 THR D N   1 
ATOM   11586 C CA  . THR D 1 289 ? 51.146  27.361  36.240 1.00 54.12  ? 491 THR D CA  1 
ATOM   11587 C C   . THR D 1 289 ? 51.860  28.196  35.188 1.00 55.95  ? 491 THR D C   1 
ATOM   11588 O O   . THR D 1 289 ? 51.452  29.335  34.945 1.00 57.05  ? 491 THR D O   1 
ATOM   11589 C CB  . THR D 1 289 ? 51.492  27.889  37.633 1.00 60.37  ? 491 THR D CB  1 
ATOM   11590 O OG1 . THR D 1 289 ? 52.885  27.682  37.892 1.00 63.77  ? 491 THR D OG1 1 
ATOM   11591 C CG2 . THR D 1 289 ? 50.672  27.177  38.690 1.00 59.26  ? 491 THR D CG2 1 
ATOM   11592 N N   . THR D 1 290 ? 52.907  27.663  34.566 1.00 53.84  ? 492 THR D N   1 
ATOM   11593 C CA  . THR D 1 290 ? 53.540  28.286  33.410 1.00 54.93  ? 492 THR D CA  1 
ATOM   11594 C C   . THR D 1 290 ? 52.888  27.688  32.171 1.00 54.66  ? 492 THR D C   1 
ATOM   11595 O O   . THR D 1 290 ? 53.040  26.495  31.894 1.00 54.78  ? 492 THR D O   1 
ATOM   11596 C CB  . THR D 1 290 ? 55.049  28.057  33.412 1.00 57.03  ? 492 THR D CB  1 
ATOM   11597 O OG1 . THR D 1 290 ? 55.614  28.623  34.601 1.00 59.39  ? 492 THR D OG1 1 
ATOM   11598 C CG2 . THR D 1 290 ? 55.682  28.714  32.200 1.00 56.87  ? 492 THR D CG2 1 
ATOM   11599 N N   . VAL D 1 291 ? 52.162  28.522  31.428 1.00 57.12  ? 493 VAL D N   1 
ATOM   11600 C CA  . VAL D 1 291 ? 51.247  28.009  30.414 1.00 56.89  ? 493 VAL D CA  1 
ATOM   11601 C C   . VAL D 1 291 ? 52.011  27.443  29.224 1.00 56.38  ? 493 VAL D C   1 
ATOM   11602 O O   . VAL D 1 291 ? 51.509  26.568  28.511 1.00 56.25  ? 493 VAL D O   1 
ATOM   11603 C CB  . VAL D 1 291 ? 50.264  29.113  29.989 1.00 55.15  ? 493 VAL D CB  1 
ATOM   11604 C CG1 . VAL D 1 291 ? 49.422  29.540  31.173 1.00 56.81  ? 493 VAL D CG1 1 
ATOM   11605 C CG2 . VAL D 1 291 ? 51.017  30.301  29.422 1.00 55.02  ? 493 VAL D CG2 1 
ATOM   11606 N N   . THR D 1 292 ? 53.234  27.924  28.989 1.00 56.98  ? 494 THR D N   1 
ATOM   11607 C CA  . THR D 1 292 ? 54.000  27.437  27.844 1.00 56.41  ? 494 THR D CA  1 
ATOM   11608 C C   . THR D 1 292 ? 54.384  25.972  28.017 1.00 56.19  ? 494 THR D C   1 
ATOM   11609 O O   . THR D 1 292 ? 54.656  25.272  27.035 1.00 56.30  ? 494 THR D O   1 
ATOM   11610 C CB  . THR D 1 292 ? 55.248  28.293  27.637 1.00 58.16  ? 494 THR D CB  1 
ATOM   11611 O OG1 . THR D 1 292 ? 56.071  28.232  28.808 1.00 58.42  ? 494 THR D OG1 1 
ATOM   11612 C CG2 . THR D 1 292 ? 54.860  29.735  27.375 1.00 57.20  ? 494 THR D CG2 1 
ATOM   11613 N N   . GLN D 1 293 ? 54.409  25.491  29.260 1.00 56.85  ? 495 GLN D N   1 
ATOM   11614 C CA  . GLN D 1 293 ? 54.738  24.092  29.499 1.00 56.01  ? 495 GLN D CA  1 
ATOM   11615 C C   . GLN D 1 293 ? 53.513  23.205  29.313 1.00 55.60  ? 495 GLN D C   1 
ATOM   11616 O O   . GLN D 1 293 ? 53.633  21.979  29.211 1.00 56.02  ? 495 GLN D O   1 
ATOM   11617 C CB  . GLN D 1 293 ? 55.325  23.934  30.900 1.00 53.48  ? 495 GLN D CB  1 
ATOM   11618 C CG  . GLN D 1 293 ? 56.626  24.699  31.088 1.00 55.96  ? 495 GLN D CG  1 
ATOM   11619 C CD  . GLN D 1 293 ? 57.171  24.605  32.498 1.00 57.83  ? 495 GLN D CD  1 
ATOM   11620 O OE1 . GLN D 1 293 ? 56.436  24.325  33.444 1.00 59.61  ? 495 GLN D OE1 1 
ATOM   11621 N NE2 . GLN D 1 293 ? 58.465  24.858  32.648 1.00 59.18  ? 495 GLN D NE2 1 
ATOM   11622 N N   . ASN D 1 294 ? 52.343  23.821  29.187 1.00 52.10  ? 496 ASN D N   1 
ATOM   11623 C CA  . ASN D 1 294 ? 51.117  23.071  28.954 1.00 51.42  ? 496 ASN D CA  1 
ATOM   11624 C C   . ASN D 1 294 ? 50.946  22.818  27.464 1.00 51.96  ? 496 ASN D C   1 
ATOM   11625 O O   . ASN D 1 294 ? 51.546  23.500  26.640 1.00 51.89  ? 496 ASN D O   1 
ATOM   11626 C CB  . ASN D 1 294 ? 49.908  23.836  29.481 1.00 52.99  ? 496 ASN D CB  1 
ATOM   11627 C CG  . ASN D 1 294 ? 49.809  23.799  30.988 1.00 53.02  ? 496 ASN D CG  1 
ATOM   11628 O OD1 . ASN D 1 294 ? 50.664  23.237  31.666 1.00 51.76  ? 496 ASN D OD1 1 
ATOM   11629 N ND2 . ASN D 1 294 ? 48.754  24.390  31.520 1.00 54.31  ? 496 ASN D ND2 1 
ATOM   11630 N N   . ASN D 1 295 ? 50.151  21.811  27.126 1.00 50.94  ? 497 ASN D N   1 
ATOM   11631 C CA  . ASN D 1 295 ? 49.872  21.476  25.736 1.00 51.70  ? 497 ASN D CA  1 
ATOM   11632 C C   . ASN D 1 295 ? 48.969  22.539  25.111 1.00 52.58  ? 497 ASN D C   1 
ATOM   11633 O O   . ASN D 1 295 ? 48.074  23.064  25.771 1.00 52.32  ? 497 ASN D O   1 
ATOM   11634 C CB  . ASN D 1 295 ? 49.210  20.105  25.651 1.00 52.87  ? 497 ASN D CB  1 
ATOM   11635 C CG  . ASN D 1 295 ? 49.044  19.626  24.228 1.00 54.10  ? 497 ASN D CG  1 
ATOM   11636 O OD1 . ASN D 1 295 ? 50.018  19.458  23.502 1.00 54.54  ? 497 ASN D OD1 1 
ATOM   11637 N ND2 . ASN D 1 295 ? 47.806  19.416  23.819 1.00 54.34  ? 497 ASN D ND2 1 
ATOM   11638 N N   . ASN D 1 296 ? 49.190  22.841  23.835 1.00 50.51  ? 498 ASN D N   1 
ATOM   11639 C CA  . ASN D 1 296 ? 48.402  23.840  23.128 1.00 51.66  ? 498 ASN D CA  1 
ATOM   11640 C C   . ASN D 1 296 ? 47.104  23.241  22.586 1.00 52.37  ? 498 ASN D C   1 
ATOM   11641 O O   . ASN D 1 296 ? 46.942  23.069  21.382 1.00 52.93  ? 498 ASN D O   1 
ATOM   11642 C CB  . ASN D 1 296 ? 49.234  24.406  21.982 1.00 56.01  ? 498 ASN D CB  1 
ATOM   11643 C CG  . ASN D 1 296 ? 48.533  25.518  21.244 1.00 56.12  ? 498 ASN D CG  1 
ATOM   11644 O OD1 . ASN D 1 296 ? 47.590  26.111  21.748 1.00 55.83  ? 498 ASN D OD1 1 
ATOM   11645 N ND2 . ASN D 1 296 ? 49.000  25.812  20.042 1.00 57.08  ? 498 ASN D ND2 1 
ATOM   11646 N N   . SER D 1 297 ? 46.180  22.932  23.490 1.00 47.48  ? 499 SER D N   1 
ATOM   11647 C CA  . SER D 1 297 ? 44.892  22.342  23.135 1.00 48.36  ? 499 SER D CA  1 
ATOM   11648 C C   . SER D 1 297 ? 43.879  22.579  24.244 1.00 48.51  ? 499 SER D C   1 
ATOM   11649 O O   . SER D 1 297 ? 44.244  23.000  25.334 1.00 48.19  ? 499 SER D O   1 
ATOM   11650 C CB  . SER D 1 297 ? 45.037  20.840  22.879 1.00 49.03  ? 499 SER D CB  1 
ATOM   11651 O OG  . SER D 1 297 ? 45.354  20.139  24.069 1.00 49.92  ? 499 SER D OG  1 
ATOM   11652 N N   . GLU D 1 298 ? 42.603  22.340  23.967 1.00 43.56  ? 500 GLU D N   1 
ATOM   11653 C CA  . GLU D 1 298 ? 41.594  22.506  25.001 1.00 44.07  ? 500 GLU D CA  1 
ATOM   11654 C C   . GLU D 1 298 ? 41.367  21.163  25.686 1.00 43.30  ? 500 GLU D C   1 
ATOM   11655 O O   . GLU D 1 298 ? 40.664  20.302  25.171 1.00 43.71  ? 500 GLU D O   1 
ATOM   11656 C CB  . GLU D 1 298 ? 40.287  23.013  24.401 1.00 40.92  ? 500 GLU D CB  1 
ATOM   11657 C CG  . GLU D 1 298 ? 39.122  23.005  25.374 1.00 44.99  ? 500 GLU D CG  1 
ATOM   11658 C CD  . GLU D 1 298 ? 39.386  23.835  26.614 1.00 47.35  ? 500 GLU D CD  1 
ATOM   11659 O OE1 . GLU D 1 298 ? 40.344  24.626  26.611 1.00 48.61  ? 500 GLU D OE1 1 
ATOM   11660 O OE2 . GLU D 1 298 ? 38.630  23.700  27.595 1.00 47.46  ? 500 GLU D OE2 1 
ATOM   11661 N N   . PHE D 1 299 ? 41.971  20.996  26.855 1.00 39.88  ? 501 PHE D N   1 
ATOM   11662 C CA  . PHE D 1 299 ? 41.852  19.765  27.613 1.00 38.81  ? 501 PHE D CA  1 
ATOM   11663 C C   . PHE D 1 299 ? 41.221  19.941  28.986 1.00 38.35  ? 501 PHE D C   1 
ATOM   11664 O O   . PHE D 1 299 ? 41.390  19.092  29.847 1.00 38.57  ? 501 PHE D O   1 
ATOM   11665 C CB  . PHE D 1 299 ? 43.212  19.080  27.745 1.00 42.59  ? 501 PHE D CB  1 
ATOM   11666 C CG  . PHE D 1 299 ? 44.230  19.885  28.501 1.00 41.76  ? 501 PHE D CG  1 
ATOM   11667 C CD1 . PHE D 1 299 ? 44.311  19.803  29.876 1.00 41.38  ? 501 PHE D CD1 1 
ATOM   11668 C CD2 . PHE D 1 299 ? 45.113  20.708  27.833 1.00 41.44  ? 501 PHE D CD2 1 
ATOM   11669 C CE1 . PHE D 1 299 ? 45.247  20.533  30.573 1.00 40.91  ? 501 PHE D CE1 1 
ATOM   11670 C CE2 . PHE D 1 299 ? 46.054  21.440  28.524 1.00 40.84  ? 501 PHE D CE2 1 
ATOM   11671 C CZ  . PHE D 1 299 ? 46.121  21.354  29.896 1.00 40.57  ? 501 PHE D CZ  1 
ATOM   11672 N N   . ALA D 1 300 ? 40.533  21.049  29.215 1.00 37.82  ? 502 ALA D N   1 
ATOM   11673 C CA  . ALA D 1 300 ? 39.913  21.265  30.517 1.00 36.87  ? 502 ALA D CA  1 
ATOM   11674 C C   . ALA D 1 300 ? 38.944  20.137  30.832 1.00 36.68  ? 502 ALA D C   1 
ATOM   11675 O O   . ALA D 1 300 ? 39.022  19.527  31.889 1.00 36.60  ? 502 ALA D O   1 
ATOM   11676 C CB  . ALA D 1 300 ? 39.216  22.611  30.567 1.00 40.57  ? 502 ALA D CB  1 
ATOM   11677 N N   . TRP D 1 301 ? 38.032  19.867  29.906 1.00 33.28  ? 503 TRP D N   1 
ATOM   11678 C CA  . TRP D 1 301 ? 37.059  18.792  30.045 1.00 33.82  ? 503 TRP D CA  1 
ATOM   11679 C C   . TRP D 1 301 ? 37.576  17.456  29.504 1.00 33.50  ? 503 TRP D C   1 
ATOM   11680 O O   . TRP D 1 301 ? 37.519  16.453  30.226 1.00 33.48  ? 503 TRP D O   1 
ATOM   11681 C CB  . TRP D 1 301 ? 35.738  19.184  29.380 1.00 29.96  ? 503 TRP D CB  1 
ATOM   11682 C CG  . TRP D 1 301 ? 34.708  18.117  29.459 1.00 33.23  ? 503 TRP D CG  1 
ATOM   11683 C CD1 . TRP D 1 301 ? 34.251  17.344  28.438 1.00 34.09  ? 503 TRP D CD1 1 
ATOM   11684 C CD2 . TRP D 1 301 ? 34.027  17.673  30.636 1.00 34.81  ? 503 TRP D CD2 1 
ATOM   11685 N NE1 . TRP D 1 301 ? 33.309  16.459  28.899 1.00 34.73  ? 503 TRP D NE1 1 
ATOM   11686 C CE2 . TRP D 1 301 ? 33.156  16.640  30.248 1.00 35.09  ? 503 TRP D CE2 1 
ATOM   11687 C CE3 . TRP D 1 301 ? 34.064  18.056  31.978 1.00 35.58  ? 503 TRP D CE3 1 
ATOM   11688 C CZ2 . TRP D 1 301 ? 32.327  15.984  31.155 1.00 35.87  ? 503 TRP D CZ2 1 
ATOM   11689 C CZ3 . TRP D 1 301 ? 33.242  17.404  32.876 1.00 36.19  ? 503 TRP D CZ3 1 
ATOM   11690 C CH2 . TRP D 1 301 ? 32.385  16.380  32.461 1.00 36.39  ? 503 TRP D CH2 1 
ATOM   11691 N N   . PRO D 1 302 ? 38.081  17.379  28.263 1.00 33.21  ? 504 PRO D N   1 
ATOM   11692 C CA  . PRO D 1 302 ? 38.463  16.061  27.725 1.00 32.94  ? 504 PRO D CA  1 
ATOM   11693 C C   . PRO D 1 302 ? 39.556  15.356  28.508 1.00 33.38  ? 504 PRO D C   1 
ATOM   11694 O O   . PRO D 1 302 ? 39.600  14.121  28.510 1.00 34.95  ? 504 PRO D O   1 
ATOM   11695 C CB  . PRO D 1 302 ? 38.927  16.393  26.300 1.00 32.92  ? 504 PRO D CB  1 
ATOM   11696 C CG  . PRO D 1 302 ? 38.213  17.630  25.959 1.00 32.24  ? 504 PRO D CG  1 
ATOM   11697 C CD  . PRO D 1 302 ? 38.209  18.420  27.228 1.00 33.64  ? 504 PRO D CD  1 
ATOM   11698 N N   . GLY D 1 303 ? 40.442  16.095  29.164 1.00 37.58  ? 505 GLY D N   1 
ATOM   11699 C CA  . GLY D 1 303 ? 41.559  15.504  29.873 1.00 37.88  ? 505 GLY D CA  1 
ATOM   11700 C C   . GLY D 1 303 ? 41.322  15.359  31.361 1.00 37.52  ? 505 GLY D C   1 
ATOM   11701 O O   . GLY D 1 303 ? 42.273  15.322  32.144 1.00 38.45  ? 505 GLY D O   1 
ATOM   11702 N N   . ALA D 1 304 ? 40.061  15.283  31.765 1.00 34.42  ? 506 ALA D N   1 
ATOM   11703 C CA  . ALA D 1 304 ? 39.687  15.321  33.169 1.00 33.19  ? 506 ALA D CA  1 
ATOM   11704 C C   . ALA D 1 304 ? 39.182  13.965  33.645 1.00 32.52  ? 506 ALA D C   1 
ATOM   11705 O O   . ALA D 1 304 ? 38.641  13.173  32.870 1.00 33.37  ? 506 ALA D O   1 
ATOM   11706 C CB  . ALA D 1 304 ? 38.615  16.383  33.403 1.00 28.88  ? 506 ALA D CB  1 
ATOM   11707 N N   . SER D 1 305 ? 39.374  13.705  34.936 1.00 32.10  ? 507 SER D N   1 
ATOM   11708 C CA  . SER D 1 305 ? 38.898  12.474  35.550 1.00 30.94  ? 507 SER D CA  1 
ATOM   11709 C C   . SER D 1 305 ? 37.438  12.624  35.953 1.00 29.89  ? 507 SER D C   1 
ATOM   11710 O O   . SER D 1 305 ? 37.066  13.593  36.619 1.00 29.39  ? 507 SER D O   1 
ATOM   11711 C CB  . SER D 1 305 ? 39.744  12.120  36.771 1.00 30.40  ? 507 SER D CB  1 
ATOM   11712 O OG  . SER D 1 305 ? 41.075  11.831  36.399 1.00 32.39  ? 507 SER D OG  1 
ATOM   11713 N N   . SER D 1 306 ? 36.617  11.655  35.566 1.00 26.69  ? 508 SER D N   1 
ATOM   11714 C CA  . SER D 1 306 ? 35.184  11.733  35.786 1.00 25.75  ? 508 SER D CA  1 
ATOM   11715 C C   . SER D 1 306 ? 34.654  10.382  36.237 1.00 24.94  ? 508 SER D C   1 
ATOM   11716 O O   . SER D 1 306 ? 35.335  9.362   36.122 1.00 25.47  ? 508 SER D O   1 
ATOM   11717 C CB  . SER D 1 306 ? 34.457  12.176  34.514 1.00 26.73  ? 508 SER D CB  1 
ATOM   11718 O OG  . SER D 1 306 ? 34.642  11.229  33.479 1.00 26.82  ? 508 SER D OG  1 
ATOM   11719 N N   . TRP D 1 307 ? 33.434  10.391  36.765 1.00 21.66  ? 509 TRP D N   1 
ATOM   11720 C CA  . TRP D 1 307 ? 32.677  9.177   37.031 1.00 21.10  ? 509 TRP D CA  1 
ATOM   11721 C C   . TRP D 1 307 ? 31.314  9.284   36.368 1.00 20.68  ? 509 TRP D C   1 
ATOM   11722 O O   . TRP D 1 307 ? 30.735  10.371  36.300 1.00 19.07  ? 509 TRP D O   1 
ATOM   11723 C CB  . TRP D 1 307 ? 32.538  8.909   38.533 1.00 18.30  ? 509 TRP D CB  1 
ATOM   11724 C CG  . TRP D 1 307 ? 32.064  10.063  39.371 1.00 18.97  ? 509 TRP D CG  1 
ATOM   11725 C CD1 . TRP D 1 307 ? 32.843  10.967  40.028 1.00 19.43  ? 509 TRP D CD1 1 
ATOM   11726 C CD2 . TRP D 1 307 ? 30.707  10.432  39.644 1.00 19.34  ? 509 TRP D CD2 1 
ATOM   11727 N NE1 . TRP D 1 307 ? 32.059  11.870  40.699 1.00 20.02  ? 509 TRP D NE1 1 
ATOM   11728 C CE2 . TRP D 1 307 ? 30.743  11.565  40.477 1.00 19.94  ? 509 TRP D CE2 1 
ATOM   11729 C CE3 . TRP D 1 307 ? 29.468  9.919   39.262 1.00 19.78  ? 509 TRP D CE3 1 
ATOM   11730 C CZ2 . TRP D 1 307 ? 29.591  12.188  40.936 1.00 20.46  ? 509 TRP D CZ2 1 
ATOM   11731 C CZ3 . TRP D 1 307 ? 28.327  10.534  39.724 1.00 20.54  ? 509 TRP D CZ3 1 
ATOM   11732 C CH2 . TRP D 1 307 ? 28.395  11.657  40.550 1.00 21.11  ? 509 TRP D CH2 1 
ATOM   11733 N N   . ALA D 1 308 ? 30.813  8.159   35.870 1.00 18.88  ? 510 ALA D N   1 
ATOM   11734 C CA  . ALA D 1 308 ? 29.568  8.105   35.119 1.00 19.23  ? 510 ALA D CA  1 
ATOM   11735 C C   . ALA D 1 308 ? 28.487  7.446   35.960 1.00 20.21  ? 510 ALA D C   1 
ATOM   11736 O O   . ALA D 1 308 ? 28.705  6.370   36.526 1.00 21.44  ? 510 ALA D O   1 
ATOM   11737 C CB  . ALA D 1 308 ? 29.750  7.337   33.811 1.00 21.20  ? 510 ALA D CB  1 
ATOM   11738 N N   . LEU D 1 309 ? 27.326  8.089   36.036 1.00 16.98  ? 511 LEU D N   1 
ATOM   11739 C CA  . LEU D 1 309 ? 26.188  7.578   36.785 1.00 17.56  ? 511 LEU D CA  1 
ATOM   11740 C C   . LEU D 1 309 ? 24.936  7.736   35.937 1.00 18.73  ? 511 LEU D C   1 
ATOM   11741 O O   . LEU D 1 309 ? 24.563  8.859   35.586 1.00 18.54  ? 511 LEU D O   1 
ATOM   11742 C CB  . LEU D 1 309 ? 26.039  8.327   38.106 1.00 15.83  ? 511 LEU D CB  1 
ATOM   11743 C CG  . LEU D 1 309 ? 24.971  7.886   39.097 1.00 15.89  ? 511 LEU D CG  1 
ATOM   11744 C CD1 . LEU D 1 309 ? 25.310  6.517   39.638 1.00 16.06  ? 511 LEU D CD1 1 
ATOM   11745 C CD2 . LEU D 1 309 ? 24.874  8.895   40.210 1.00 15.75  ? 511 LEU D CD2 1 
ATOM   11746 N N   . ASN D 1 310 ? 24.294  6.614   35.608 1.00 16.29  ? 512 ASN D N   1 
ATOM   11747 C CA  . ASN D 1 310 ? 23.101  6.597   34.757 1.00 18.12  ? 512 ASN D CA  1 
ATOM   11748 C C   . ASN D 1 310 ? 23.390  7.252   33.405 1.00 18.77  ? 512 ASN D C   1 
ATOM   11749 O O   . ASN D 1 310 ? 22.565  7.978   32.847 1.00 19.28  ? 512 ASN D O   1 
ATOM   11750 C CB  . ASN D 1 310 ? 21.919  7.275   35.459 1.00 19.34  ? 512 ASN D CB  1 
ATOM   11751 C CG  . ASN D 1 310 ? 20.580  6.966   34.806 1.00 21.61  ? 512 ASN D CG  1 
ATOM   11752 O OD1 . ASN D 1 310 ? 20.515  6.496   33.674 1.00 23.56  ? 512 ASN D OD1 1 
ATOM   11753 N ND2 . ASN D 1 310 ? 19.502  7.247   35.522 1.00 20.94  ? 512 ASN D ND2 1 
ATOM   11754 N N   . GLY D 1 311 ? 24.584  7.006   32.877 1.00 18.22  ? 513 GLY D N   1 
ATOM   11755 C CA  . GLY D 1 311 ? 24.954  7.537   31.582 1.00 18.20  ? 513 GLY D CA  1 
ATOM   11756 C C   . GLY D 1 311 ? 25.411  8.978   31.567 1.00 19.04  ? 513 GLY D C   1 
ATOM   11757 O O   . GLY D 1 311 ? 25.771  9.482   30.498 1.00 20.34  ? 513 GLY D O   1 
ATOM   11758 N N   . ARG D 1 312 ? 25.410  9.659   32.710 1.00 21.01  ? 514 ARG D N   1 
ATOM   11759 C CA  . ARG D 1 312 ? 25.849  11.044  32.807 1.00 21.40  ? 514 ARG D CA  1 
ATOM   11760 C C   . ARG D 1 312 ? 27.245  11.087  33.403 1.00 21.15  ? 514 ARG D C   1 
ATOM   11761 O O   . ARG D 1 312 ? 27.517  10.411  34.399 1.00 21.67  ? 514 ARG D O   1 
ATOM   11762 C CB  . ARG D 1 312 ? 24.895  11.877  33.663 1.00 17.05  ? 514 ARG D CB  1 
ATOM   11763 C CG  . ARG D 1 312 ? 23.538  12.084  33.046 1.00 21.05  ? 514 ARG D CG  1 
ATOM   11764 C CD  . ARG D 1 312 ? 22.618  12.804  34.001 1.00 25.10  ? 514 ARG D CD  1 
ATOM   11765 N NE  . ARG D 1 312 ? 22.386  12.018  35.204 1.00 29.29  ? 514 ARG D NE  1 
ATOM   11766 C CZ  . ARG D 1 312 ? 21.591  12.393  36.198 1.00 31.71  ? 514 ARG D CZ  1 
ATOM   11767 N NH1 . ARG D 1 312 ? 20.945  13.544  36.132 1.00 32.35  ? 514 ARG D NH1 1 
ATOM   11768 N NH2 . ARG D 1 312 ? 21.441  11.612  37.255 1.00 32.72  ? 514 ARG D NH2 1 
ATOM   11769 N N   . ASN D 1 313 ? 28.114  11.916  32.840 1.00 25.34  ? 515 ASN D N   1 
ATOM   11770 C CA  . ASN D 1 313 ? 29.473  12.032  33.341 1.00 24.55  ? 515 ASN D CA  1 
ATOM   11771 C C   . ASN D 1 313 ? 29.636  13.217  34.271 1.00 23.14  ? 515 ASN D C   1 
ATOM   11772 O O   . ASN D 1 313 ? 29.290  14.331  33.926 1.00 23.34  ? 515 ASN D O   1 
ATOM   11773 C CB  . ASN D 1 313 ? 30.453  12.161  32.186 1.00 26.21  ? 515 ASN D CB  1 
ATOM   11774 C CG  . ASN D 1 313 ? 30.499  10.925  31.328 1.00 27.82  ? 515 ASN D CG  1 
ATOM   11775 O OD1 . ASN D 1 313 ? 30.709  9.825   31.822 1.00 28.68  ? 515 ASN D OD1 1 
ATOM   11776 N ND2 . ASN D 1 313 ? 30.306  11.099  30.034 1.00 29.68  ? 515 ASN D ND2 1 
ATOM   11777 N N   . SER D 1 314 ? 30.166  12.968  35.456 1.00 24.45  ? 516 SER D N   1 
ATOM   11778 C CA  . SER D 1 314 ? 30.394  14.026  36.423 1.00 23.48  ? 516 SER D CA  1 
ATOM   11779 C C   . SER D 1 314 ? 31.871  14.055  36.750 1.00 23.14  ? 516 SER D C   1 
ATOM   11780 O O   . SER D 1 314 ? 32.491  13.015  36.909 1.00 22.80  ? 516 SER D O   1 
ATOM   11781 C CB  . SER D 1 314 ? 29.566  13.809  37.682 1.00 22.92  ? 516 SER D CB  1 
ATOM   11782 O OG  . SER D 1 314 ? 28.195  14.026  37.422 1.00 24.30  ? 516 SER D OG  1 
ATOM   11783 N N   . LEU D 1 315 ? 32.439  15.247  36.830 1.00 25.34  ? 517 LEU D N   1 
ATOM   11784 C CA  . LEU D 1 315 ? 33.855  15.393  37.115 1.00 25.65  ? 517 LEU D CA  1 
ATOM   11785 C C   . LEU D 1 315 ? 34.211  14.861  38.497 1.00 26.08  ? 517 LEU D C   1 
ATOM   11786 O O   . LEU D 1 315 ? 33.456  15.031  39.444 1.00 26.93  ? 517 LEU D O   1 
ATOM   11787 C CB  . LEU D 1 315 ? 34.242  16.867  37.023 1.00 28.14  ? 517 LEU D CB  1 
ATOM   11788 C CG  . LEU D 1 315 ? 35.703  17.215  36.777 1.00 28.91  ? 517 LEU D CG  1 
ATOM   11789 C CD1 . LEU D 1 315 ? 35.974  17.173  35.287 1.00 28.72  ? 517 LEU D CD1 1 
ATOM   11790 C CD2 . LEU D 1 315 ? 35.999  18.602  37.315 1.00 30.76  ? 517 LEU D CD2 1 
ATOM   11791 N N   . MET D 1 316 ? 35.364  14.210  38.605 1.00 29.64  ? 518 MET D N   1 
ATOM   11792 C CA  . MET D 1 316 ? 35.841  13.682  39.876 1.00 29.55  ? 518 MET D CA  1 
ATOM   11793 C C   . MET D 1 316 ? 36.584  14.792  40.620 1.00 29.35  ? 518 MET D C   1 
ATOM   11794 O O   . MET D 1 316 ? 37.807  14.811  40.668 1.00 29.17  ? 518 MET D O   1 
ATOM   11795 C CB  . MET D 1 316 ? 36.758  12.479  39.642 1.00 28.36  ? 518 MET D CB  1 
ATOM   11796 C CG  . MET D 1 316 ? 37.577  12.057  40.848 1.00 29.72  ? 518 MET D CG  1 
ATOM   11797 S SD  . MET D 1 316 ? 36.654  11.155  42.103 1.00 32.41  ? 518 MET D SD  1 
ATOM   11798 C CE  . MET D 1 316 ? 36.382  9.583   41.296 1.00 30.17  ? 518 MET D CE  1 
ATOM   11799 N N   . ASN D 1 317 ? 35.819  15.720  41.183 1.00 31.94  ? 519 ASN D N   1 
ATOM   11800 C CA  . ASN D 1 317 ? 36.342  16.864  41.906 1.00 31.35  ? 519 ASN D CA  1 
ATOM   11801 C C   . ASN D 1 317 ? 35.731  16.884  43.288 1.00 31.13  ? 519 ASN D C   1 
ATOM   11802 O O   . ASN D 1 317 ? 34.524  16.753  43.419 1.00 31.91  ? 519 ASN D O   1 
ATOM   11803 C CB  . ASN D 1 317 ? 35.935  18.136  41.169 1.00 32.75  ? 519 ASN D CB  1 
ATOM   11804 C CG  . ASN D 1 317 ? 36.860  19.298  41.443 1.00 33.19  ? 519 ASN D CG  1 
ATOM   11805 O OD1 . ASN D 1 317 ? 37.462  19.848  40.527 1.00 35.54  ? 519 ASN D OD1 1 
ATOM   11806 N ND2 . ASN D 1 317 ? 36.976  19.680  42.702 1.00 31.93  ? 519 ASN D ND2 1 
ATOM   11807 N N   . PRO D 1 318 ? 36.542  17.084  44.331 1.00 35.44  ? 520 PRO D N   1 
ATOM   11808 C CA  . PRO D 1 318 ? 37.985  16.880  44.494 1.00 35.25  ? 520 PRO D CA  1 
ATOM   11809 C C   . PRO D 1 318 ? 38.397  15.411  44.358 1.00 35.79  ? 520 PRO D C   1 
ATOM   11810 O O   . PRO D 1 318 ? 39.477  15.119  43.861 1.00 35.55  ? 520 PRO D O   1 
ATOM   11811 C CB  . PRO D 1 318 ? 38.262  17.409  45.905 1.00 33.70  ? 520 PRO D CB  1 
ATOM   11812 C CG  . PRO D 1 318 ? 36.953  17.372  46.596 1.00 33.71  ? 520 PRO D CG  1 
ATOM   11813 C CD  . PRO D 1 318 ? 35.936  17.655  45.542 1.00 34.53  ? 520 PRO D CD  1 
ATOM   11814 N N   . GLY D 1 319 ? 37.559  14.503  44.838 1.00 35.06  ? 521 GLY D N   1 
ATOM   11815 C CA  . GLY D 1 319 ? 37.855  13.087  44.761 1.00 36.08  ? 521 GLY D CA  1 
ATOM   11816 C C   . GLY D 1 319 ? 38.738  12.619  45.895 1.00 36.90  ? 521 GLY D C   1 
ATOM   11817 O O   . GLY D 1 319 ? 38.878  13.314  46.893 1.00 37.39  ? 521 GLY D O   1 
ATOM   11818 N N   . PRO D 1 320 ? 39.312  11.421  45.763 1.00 43.36  ? 522 PRO D N   1 
ATOM   11819 C CA  . PRO D 1 320 ? 40.193  10.874  46.796 1.00 43.09  ? 522 PRO D CA  1 
ATOM   11820 C C   . PRO D 1 320 ? 41.292  11.856  47.195 1.00 42.80  ? 522 PRO D C   1 
ATOM   11821 O O   . PRO D 1 320 ? 41.921  12.480  46.346 1.00 43.88  ? 522 PRO D O   1 
ATOM   11822 C CB  . PRO D 1 320 ? 40.794  9.646   46.119 1.00 39.28  ? 522 PRO D CB  1 
ATOM   11823 C CG  . PRO D 1 320 ? 39.747  9.217   45.157 1.00 40.60  ? 522 PRO D CG  1 
ATOM   11824 C CD  . PRO D 1 320 ? 39.106  10.477  44.655 1.00 40.02  ? 522 PRO D CD  1 
ATOM   11825 N N   . ALA D 1 321 ? 41.505  11.983  48.497 1.00 46.06  ? 523 ALA D N   1 
ATOM   11826 C CA  . ALA D 1 321 ? 42.506  12.887  49.047 1.00 45.86  ? 523 ALA D CA  1 
ATOM   11827 C C   . ALA D 1 321 ? 43.898  12.371  48.717 1.00 45.97  ? 523 ALA D C   1 
ATOM   11828 O O   . ALA D 1 321 ? 44.268  11.261  49.117 1.00 45.66  ? 523 ALA D O   1 
ATOM   11829 C CB  . ALA D 1 321 ? 42.328  13.023  50.556 1.00 43.04  ? 523 ALA D CB  1 
ATOM   11830 N N   . MET D 1 322 ? 44.670  13.181  47.996 1.00 46.26  ? 524 MET D N   1 
ATOM   11831 C CA  . MET D 1 322 ? 46.009  12.817  47.560 1.00 47.09  ? 524 MET D CA  1 
ATOM   11832 C C   . MET D 1 322 ? 46.886  14.057  47.547 1.00 47.51  ? 524 MET D C   1 
ATOM   11833 O O   . MET D 1 322 ? 46.391  15.185  47.501 1.00 49.10  ? 524 MET D O   1 
ATOM   11834 C CB  . MET D 1 322 ? 45.996  12.182  46.169 1.00 44.98  ? 524 MET D CB  1 
ATOM   11835 C CG  . MET D 1 322 ? 45.368  10.812  46.120 1.00 47.68  ? 524 MET D CG  1 
ATOM   11836 S SD  . MET D 1 322 ? 45.304  10.194  44.439 1.00 51.27  ? 524 MET D SD  1 
ATOM   11837 C CE  . MET D 1 322 ? 43.973  11.208  43.819 1.00 53.35  ? 524 MET D CE  1 
ATOM   11838 N N   . ALA D 1 323 ? 48.196  13.834  47.589 1.00 49.09  ? 525 ALA D N   1 
ATOM   11839 C CA  . ALA D 1 323 ? 49.141  14.937  47.544 1.00 50.09  ? 525 ALA D CA  1 
ATOM   11840 C C   . ALA D 1 323 ? 49.059  15.648  46.202 1.00 51.46  ? 525 ALA D C   1 
ATOM   11841 O O   . ALA D 1 323 ? 48.949  15.015  45.149 1.00 51.92  ? 525 ALA D O   1 
ATOM   11842 C CB  . ALA D 1 323 ? 50.559  14.431  47.785 1.00 50.31  ? 525 ALA D CB  1 
ATOM   11843 N N   . SER D 1 324 ? 49.094  16.971  46.246 1.00 56.29  ? 526 SER D N   1 
ATOM   11844 C CA  . SER D 1 324 ? 48.987  17.769  45.039 1.00 58.08  ? 526 SER D CA  1 
ATOM   11845 C C   . SER D 1 324 ? 50.201  17.633  44.137 1.00 59.25  ? 526 SER D C   1 
ATOM   11846 O O   . SER D 1 324 ? 50.072  17.564  42.920 1.00 59.40  ? 526 SER D O   1 
ATOM   11847 C CB  . SER D 1 324 ? 48.761  19.235  45.399 1.00 54.07  ? 526 SER D CB  1 
ATOM   11848 O OG  . SER D 1 324 ? 47.629  19.378  46.239 1.00 56.80  ? 526 SER D OG  1 
ATOM   11849 N N   . HIS D 1 325 ? 51.382  17.592  44.736 1.00 58.32  ? 527 HIS D N   1 
ATOM   11850 C CA  . HIS D 1 325 ? 52.609  17.497  43.962 1.00 60.80  ? 527 HIS D CA  1 
ATOM   11851 C C   . HIS D 1 325 ? 53.742  16.815  44.716 1.00 62.34  ? 527 HIS D C   1 
ATOM   11852 O O   . HIS D 1 325 ? 53.726  16.732  45.938 1.00 62.36  ? 527 HIS D O   1 
ATOM   11853 C CB  . HIS D 1 325 ? 53.052  18.901  43.576 1.00 64.50  ? 527 HIS D CB  1 
ATOM   11854 C CG  . HIS D 1 325 ? 53.010  19.868  44.716 1.00 65.32  ? 527 HIS D CG  1 
ATOM   11855 N ND1 . HIS D 1 325 ? 53.992  19.920  45.680 1.00 65.88  ? 527 HIS D ND1 1 
ATOM   11856 C CD2 . HIS D 1 325 ? 52.103  20.814  45.052 1.00 65.35  ? 527 HIS D CD2 1 
ATOM   11857 C CE1 . HIS D 1 325 ? 53.693  20.858  46.560 1.00 64.94  ? 527 HIS D CE1 1 
ATOM   11858 N NE2 . HIS D 1 325 ? 52.552  21.416  46.202 1.00 64.88  ? 527 HIS D NE2 1 
ATOM   11859 N N   . LYS D 1 326 ? 54.730  16.335  43.969 1.00 61.22  ? 528 LYS D N   1 
ATOM   11860 C CA  . LYS D 1 326 ? 55.916  15.698  44.536 1.00 63.98  ? 528 LYS D CA  1 
ATOM   11861 C C   . LYS D 1 326 ? 56.834  16.758  45.144 1.00 65.98  ? 528 LYS D C   1 
ATOM   11862 O O   . LYS D 1 326 ? 56.754  17.932  44.790 1.00 65.50  ? 528 LYS D O   1 
ATOM   11863 C CB  . LYS D 1 326 ? 56.668  14.913  43.465 1.00 60.33  ? 528 LYS D CB  1 
ATOM   11864 C CG  . LYS D 1 326 ? 55.760  14.232  42.462 1.00 60.93  ? 528 LYS D CG  1 
ATOM   11865 C CD  . LYS D 1 326 ? 56.545  13.318  41.543 1.00 63.11  ? 528 LYS D CD  1 
ATOM   11866 C CE  . LYS D 1 326 ? 57.799  13.996  41.026 1.00 63.51  ? 528 LYS D CE  1 
ATOM   11867 N NZ  . LYS D 1 326 ? 58.447  13.178  39.967 1.00 63.91  ? 528 LYS D NZ  1 
ATOM   11868 N N   . GLU D 1 327 ? 57.733  16.349  46.030 1.00 63.83  ? 529 GLU D N   1 
ATOM   11869 C CA  . GLU D 1 327 ? 58.628  17.306  46.674 1.00 67.55  ? 529 GLU D CA  1 
ATOM   11870 C C   . GLU D 1 327 ? 59.456  18.057  45.644 1.00 68.26  ? 529 GLU D C   1 
ATOM   11871 O O   . GLU D 1 327 ? 59.950  17.474  44.682 1.00 68.30  ? 529 GLU D O   1 
ATOM   11872 C CB  . GLU D 1 327 ? 59.581  16.588  47.625 1.00 67.17  ? 529 GLU D CB  1 
ATOM   11873 C CG  . GLU D 1 327 ? 59.024  16.290  49.003 1.00 72.95  ? 529 GLU D CG  1 
ATOM   11874 C CD  . GLU D 1 327 ? 60.027  15.563  49.874 1.00 75.96  ? 529 GLU D CD  1 
ATOM   11875 O OE1 . GLU D 1 327 ? 59.952  15.693  51.114 1.00 76.35  ? 529 GLU D OE1 1 
ATOM   11876 O OE2 . GLU D 1 327 ? 60.898  14.866  49.312 1.00 77.91  ? 529 GLU D OE2 1 
ATOM   11877 N N   . GLY D 1 328 ? 59.608  19.357  45.863 1.00 69.86  ? 530 GLY D N   1 
ATOM   11878 C CA  . GLY D 1 328 ? 60.370  20.205  44.969 1.00 70.59  ? 530 GLY D CA  1 
ATOM   11879 C C   . GLY D 1 328 ? 59.619  20.744  43.765 1.00 71.08  ? 530 GLY D C   1 
ATOM   11880 O O   . GLY D 1 328 ? 60.214  21.409  42.918 1.00 72.04  ? 530 GLY D O   1 
ATOM   11881 N N   . GLU D 1 329 ? 58.323  20.465  43.670 1.00 72.54  ? 531 GLU D N   1 
ATOM   11882 C CA  . GLU D 1 329 ? 57.539  20.971  42.547 1.00 72.06  ? 531 GLU D CA  1 
ATOM   11883 C C   . GLU D 1 329 ? 56.446  21.915  43.030 1.00 70.36  ? 531 GLU D C   1 
ATOM   11884 O O   . GLU D 1 329 ? 55.612  21.540  43.842 1.00 70.34  ? 531 GLU D O   1 
ATOM   11885 C CB  . GLU D 1 329 ? 56.931  19.811  41.764 1.00 66.97  ? 531 GLU D CB  1 
ATOM   11886 C CG  . GLU D 1 329 ? 57.912  18.683  41.509 1.00 71.02  ? 531 GLU D CG  1 
ATOM   11887 C CD  . GLU D 1 329 ? 57.584  17.893  40.260 1.00 74.56  ? 531 GLU D CD  1 
ATOM   11888 O OE1 . GLU D 1 329 ? 56.395  17.841  39.878 1.00 76.73  ? 531 GLU D OE1 1 
ATOM   11889 O OE2 . GLU D 1 329 ? 58.519  17.325  39.658 1.00 75.55  ? 531 GLU D OE2 1 
ATOM   11890 N N   . ASP D 1 330 ? 56.454  23.146  42.533 1.00 69.13  ? 532 ASP D N   1 
ATOM   11891 C CA  . ASP D 1 330 ? 55.454  24.127  42.944 1.00 67.48  ? 532 ASP D CA  1 
ATOM   11892 C C   . ASP D 1 330 ? 54.570  24.652  41.820 1.00 64.29  ? 532 ASP D C   1 
ATOM   11893 O O   . ASP D 1 330 ? 53.515  25.224  42.076 1.00 63.27  ? 532 ASP D O   1 
ATOM   11894 C CB  . ASP D 1 330 ? 56.144  25.304  43.633 1.00 66.86  ? 532 ASP D CB  1 
ATOM   11895 C CG  . ASP D 1 330 ? 57.316  25.841  42.831 1.00 71.96  ? 532 ASP D CG  1 
ATOM   11896 O OD1 . ASP D 1 330 ? 57.188  25.977  41.599 1.00 74.46  ? 532 ASP D OD1 1 
ATOM   11897 O OD2 . ASP D 1 330 ? 58.367  26.129  43.435 1.00 75.10  ? 532 ASP D OD2 1 
ATOM   11898 N N   . ARG D 1 331 ? 54.985  24.439  40.579 1.00 64.07  ? 533 ARG D N   1 
ATOM   11899 C CA  . ARG D 1 331 ? 54.241  24.957  39.438 1.00 60.45  ? 533 ARG D CA  1 
ATOM   11900 C C   . ARG D 1 331 ? 53.213  23.996  38.843 1.00 59.10  ? 533 ARG D C   1 
ATOM   11901 O O   . ARG D 1 331 ? 52.577  24.309  37.841 1.00 58.32  ? 533 ARG D O   1 
ATOM   11902 C CB  . ARG D 1 331 ? 55.204  25.450  38.361 1.00 63.38  ? 533 ARG D CB  1 
ATOM   11903 C CG  . ARG D 1 331 ? 55.850  24.344  37.559 1.00 61.21  ? 533 ARG D CG  1 
ATOM   11904 C CD  . ARG D 1 331 ? 57.051  24.861  36.793 1.00 61.36  ? 533 ARG D CD  1 
ATOM   11905 N NE  . ARG D 1 331 ? 57.356  24.012  35.649 1.00 61.87  ? 533 ARG D NE  1 
ATOM   11906 C CZ  . ARG D 1 331 ? 57.947  22.827  35.735 1.00 61.99  ? 533 ARG D CZ  1 
ATOM   11907 N NH1 . ARG D 1 331 ? 58.297  22.341  36.917 1.00 62.49  ? 533 ARG D NH1 1 
ATOM   11908 N NH2 . ARG D 1 331 ? 58.182  22.126  34.637 1.00 60.28  ? 533 ARG D NH2 1 
ATOM   11909 N N   . PHE D 1 332 ? 53.059  22.830  39.457 1.00 58.39  ? 534 PHE D N   1 
ATOM   11910 C CA  . PHE D 1 332 ? 52.122  21.829  38.966 1.00 55.91  ? 534 PHE D CA  1 
ATOM   11911 C C   . PHE D 1 332 ? 50.970  21.578  39.928 1.00 54.93  ? 534 PHE D C   1 
ATOM   11912 O O   . PHE D 1 332 ? 51.179  21.412  41.123 1.00 55.93  ? 534 PHE D O   1 
ATOM   11913 C CB  . PHE D 1 332 ? 52.847  20.512  38.704 1.00 56.61  ? 534 PHE D CB  1 
ATOM   11914 C CG  . PHE D 1 332 ? 53.734  20.538  37.501 1.00 56.83  ? 534 PHE D CG  1 
ATOM   11915 C CD1 . PHE D 1 332 ? 53.278  21.043  36.301 1.00 57.29  ? 534 PHE D CD1 1 
ATOM   11916 C CD2 . PHE D 1 332 ? 55.017  20.037  37.564 1.00 57.46  ? 534 PHE D CD2 1 
ATOM   11917 C CE1 . PHE D 1 332 ? 54.091  21.063  35.188 1.00 57.47  ? 534 PHE D CE1 1 
ATOM   11918 C CE2 . PHE D 1 332 ? 55.834  20.049  36.453 1.00 57.29  ? 534 PHE D CE2 1 
ATOM   11919 C CZ  . PHE D 1 332 ? 55.371  20.564  35.263 1.00 57.20  ? 534 PHE D CZ  1 
ATOM   11920 N N   . PHE D 1 333 ? 49.750  21.564  39.405 1.00 49.47  ? 535 PHE D N   1 
ATOM   11921 C CA  . PHE D 1 333 ? 48.583  21.299  40.234 1.00 47.59  ? 535 PHE D CA  1 
ATOM   11922 C C   . PHE D 1 333 ? 47.628  20.364  39.511 1.00 46.61  ? 535 PHE D C   1 
ATOM   11923 O O   . PHE D 1 333 ? 47.457  20.467  38.303 1.00 46.12  ? 535 PHE D O   1 
ATOM   11924 C CB  . PHE D 1 333 ? 47.877  22.598  40.626 1.00 48.46  ? 535 PHE D CB  1 
ATOM   11925 C CG  . PHE D 1 333 ? 47.230  23.318  39.476 1.00 48.71  ? 535 PHE D CG  1 
ATOM   11926 C CD1 . PHE D 1 333 ? 45.926  23.036  39.107 1.00 47.75  ? 535 PHE D CD1 1 
ATOM   11927 C CD2 . PHE D 1 333 ? 47.920  24.291  38.775 1.00 48.96  ? 535 PHE D CD2 1 
ATOM   11928 C CE1 . PHE D 1 333 ? 45.327  23.701  38.054 1.00 46.62  ? 535 PHE D CE1 1 
ATOM   11929 C CE2 . PHE D 1 333 ? 47.328  24.960  37.722 1.00 47.89  ? 535 PHE D CE2 1 
ATOM   11930 C CZ  . PHE D 1 333 ? 46.029  24.664  37.361 1.00 46.78  ? 535 PHE D CZ  1 
ATOM   11931 N N   . PRO D 1 334 ? 46.993  19.442  40.253 1.00 44.47  ? 536 PRO D N   1 
ATOM   11932 C CA  . PRO D 1 334 ? 46.046  18.484  39.667 1.00 44.07  ? 536 PRO D CA  1 
ATOM   11933 C C   . PRO D 1 334 ? 44.861  19.221  39.059 1.00 43.84  ? 536 PRO D C   1 
ATOM   11934 O O   . PRO D 1 334 ? 44.423  20.223  39.610 1.00 43.63  ? 536 PRO D O   1 
ATOM   11935 C CB  . PRO D 1 334 ? 45.611  17.629  40.862 1.00 45.24  ? 536 PRO D CB  1 
ATOM   11936 C CG  . PRO D 1 334 ? 46.055  18.371  42.078 1.00 45.31  ? 536 PRO D CG  1 
ATOM   11937 C CD  . PRO D 1 334 ? 47.250  19.171  41.674 1.00 45.23  ? 536 PRO D CD  1 
ATOM   11938 N N   . LEU D 1 335 ? 44.329  18.718  37.953 1.00 39.65  ? 537 LEU D N   1 
ATOM   11939 C CA  . LEU D 1 335 ? 43.253  19.418  37.268 1.00 40.05  ? 537 LEU D CA  1 
ATOM   11940 C C   . LEU D 1 335 ? 41.979  19.631  38.080 1.00 41.01  ? 537 LEU D C   1 
ATOM   11941 O O   . LEU D 1 335 ? 41.430  20.722  38.076 1.00 41.30  ? 537 LEU D O   1 
ATOM   11942 C CB  . LEU D 1 335 ? 42.917  18.669  35.981 1.00 35.92  ? 537 LEU D CB  1 
ATOM   11943 C CG  . LEU D 1 335 ? 41.955  19.338  35.010 1.00 35.82  ? 537 LEU D CG  1 
ATOM   11944 C CD1 . LEU D 1 335 ? 41.929  18.560  33.708 1.00 35.88  ? 537 LEU D CD1 1 
ATOM   11945 C CD2 . LEU D 1 335 ? 40.564  19.429  35.609 1.00 36.73  ? 537 LEU D CD2 1 
ATOM   11946 N N   . SER D 1 336 ? 41.495  18.610  38.769 1.00 37.64  ? 538 SER D N   1 
ATOM   11947 C CA  . SER D 1 336 ? 40.300  18.784  39.587 1.00 39.06  ? 538 SER D CA  1 
ATOM   11948 C C   . SER D 1 336 ? 40.510  18.311  41.015 1.00 39.29  ? 538 SER D C   1 
ATOM   11949 O O   . SER D 1 336 ? 39.596  18.335  41.825 1.00 39.67  ? 538 SER D O   1 
ATOM   11950 C CB  . SER D 1 336 ? 39.083  18.113  38.950 1.00 35.96  ? 538 SER D CB  1 
ATOM   11951 O OG  . SER D 1 336 ? 39.406  16.834  38.439 1.00 38.89  ? 538 SER D OG  1 
ATOM   11952 N N   . GLY D 1 337 ? 41.730  17.893  41.320 1.00 42.89  ? 539 GLY D N   1 
ATOM   11953 C CA  . GLY D 1 337 ? 42.050  17.363  42.629 1.00 44.03  ? 539 GLY D CA  1 
ATOM   11954 C C   . GLY D 1 337 ? 42.267  18.329  43.770 1.00 44.62  ? 539 GLY D C   1 
ATOM   11955 O O   . GLY D 1 337 ? 42.799  17.938  44.804 1.00 46.98  ? 539 GLY D O   1 
ATOM   11956 N N   . SER D 1 338 ? 41.849  19.578  43.620 1.00 43.67  ? 540 SER D N   1 
ATOM   11957 C CA  . SER D 1 338 ? 42.054  20.523  44.708 1.00 43.70  ? 540 SER D CA  1 
ATOM   11958 C C   . SER D 1 338 ? 40.834  21.417  44.880 1.00 42.47  ? 540 SER D C   1 
ATOM   11959 O O   . SER D 1 338 ? 39.961  21.494  44.013 1.00 42.45  ? 540 SER D O   1 
ATOM   11960 C CB  . SER D 1 338 ? 43.297  21.389  44.470 1.00 48.93  ? 540 SER D CB  1 
ATOM   11961 O OG  . SER D 1 338 ? 44.473  20.600  44.467 1.00 50.48  ? 540 SER D OG  1 
ATOM   11962 N N   . LEU D 1 339 ? 40.786  22.087  46.029 1.00 42.18  ? 541 LEU D N   1 
ATOM   11963 C CA  . LEU D 1 339 ? 39.812  23.142  46.266 1.00 40.99  ? 541 LEU D CA  1 
ATOM   11964 C C   . LEU D 1 339 ? 40.378  24.475  45.801 1.00 40.77  ? 541 LEU D C   1 
ATOM   11965 O O   . LEU D 1 339 ? 41.490  24.856  46.175 1.00 41.26  ? 541 LEU D O   1 
ATOM   11966 C CB  . LEU D 1 339 ? 39.454  23.221  47.749 1.00 37.10  ? 541 LEU D CB  1 
ATOM   11967 C CG  . LEU D 1 339 ? 38.722  22.038  48.379 1.00 36.18  ? 541 LEU D CG  1 
ATOM   11968 C CD1 . LEU D 1 339 ? 38.612  22.224  49.879 1.00 35.71  ? 541 LEU D CD1 1 
ATOM   11969 C CD2 . LEU D 1 339 ? 37.347  21.884  47.762 1.00 35.56  ? 541 LEU D CD2 1 
ATOM   11970 N N   . ILE D 1 340 ? 39.607  25.188  44.987 1.00 43.86  ? 542 ILE D N   1 
ATOM   11971 C CA  . ILE D 1 340 ? 40.046  26.449  44.405 1.00 44.25  ? 542 ILE D CA  1 
ATOM   11972 C C   . ILE D 1 340 ? 39.137  27.556  44.919 1.00 43.71  ? 542 ILE D C   1 
ATOM   11973 O O   . ILE D 1 340 ? 37.945  27.588  44.593 1.00 42.71  ? 542 ILE D O   1 
ATOM   11974 C CB  . ILE D 1 340 ? 40.033  26.413  42.870 1.00 41.97  ? 542 ILE D CB  1 
ATOM   11975 C CG1 . ILE D 1 340 ? 40.966  25.322  42.360 1.00 44.81  ? 542 ILE D CG1 1 
ATOM   11976 C CG2 . ILE D 1 340 ? 40.493  27.744  42.319 1.00 43.25  ? 542 ILE D CG2 1 
ATOM   11977 C CD1 . ILE D 1 340 ? 40.828  25.055  40.884 1.00 46.65  ? 542 ILE D CD1 1 
ATOM   11978 N N   . PHE D 1 341 ? 39.700  28.464  45.708 1.00 47.69  ? 543 PHE D N   1 
ATOM   11979 C CA  . PHE D 1 341 ? 38.965  29.586  46.266 1.00 47.56  ? 543 PHE D CA  1 
ATOM   11980 C C   . PHE D 1 341 ? 39.289  30.857  45.494 1.00 46.97  ? 543 PHE D C   1 
ATOM   11981 O O   . PHE D 1 341 ? 40.415  31.053  45.032 1.00 45.80  ? 543 PHE D O   1 
ATOM   11982 C CB  . PHE D 1 341 ? 39.306  29.780  47.743 1.00 41.83  ? 543 PHE D CB  1 
ATOM   11983 C CG  . PHE D 1 341 ? 38.938  28.615  48.607 1.00 42.32  ? 543 PHE D CG  1 
ATOM   11984 C CD1 . PHE D 1 341 ? 37.650  28.473  49.087 1.00 42.40  ? 543 PHE D CD1 1 
ATOM   11985 C CD2 . PHE D 1 341 ? 39.881  27.662  48.944 1.00 42.17  ? 543 PHE D CD2 1 
ATOM   11986 C CE1 . PHE D 1 341 ? 37.309  27.402  49.884 1.00 41.95  ? 543 PHE D CE1 1 
ATOM   11987 C CE2 . PHE D 1 341 ? 39.546  26.589  49.742 1.00 41.85  ? 543 PHE D CE2 1 
ATOM   11988 C CZ  . PHE D 1 341 ? 38.257  26.458  50.210 1.00 41.71  ? 543 PHE D CZ  1 
ATOM   11989 N N   . GLY D 1 342 ? 38.291  31.720  45.352 1.00 56.03  ? 544 GLY D N   1 
ATOM   11990 C CA  . GLY D 1 342 ? 38.491  32.996  44.698 1.00 56.08  ? 544 GLY D CA  1 
ATOM   11991 C C   . GLY D 1 342 ? 38.880  34.095  45.672 1.00 56.28  ? 544 GLY D C   1 
ATOM   11992 O O   . GLY D 1 342 ? 38.549  34.053  46.853 1.00 56.82  ? 544 GLY D O   1 
ATOM   11993 N N   . LYS D 1 343 ? 39.603  35.083  45.158 1.00 63.37  ? 545 LYS D N   1 
ATOM   11994 C CA  . LYS D 1 343 ? 39.932  36.253  45.953 1.00 62.94  ? 545 LYS D CA  1 
ATOM   11995 C C   . LYS D 1 343 ? 38.710  37.153  46.104 1.00 63.54  ? 545 LYS D C   1 
ATOM   11996 O O   . LYS D 1 343 ? 37.738  37.057  45.350 1.00 62.67  ? 545 LYS D O   1 
ATOM   11997 C CB  . LYS D 1 343 ? 41.083  37.033  45.323 1.00 62.35  ? 545 LYS D CB  1 
ATOM   11998 C CG  . LYS D 1 343 ? 42.418  36.315  45.353 1.00 62.85  ? 545 LYS D CG  1 
ATOM   11999 C CD  . LYS D 1 343 ? 43.486  37.153  44.674 1.00 63.90  ? 545 LYS D CD  1 
ATOM   12000 C CE  . LYS D 1 343 ? 44.850  36.495  44.748 1.00 65.81  ? 545 LYS D CE  1 
ATOM   12001 N NZ  . LYS D 1 343 ? 45.880  37.310  44.049 1.00 67.04  ? 545 LYS D NZ  1 
ATOM   12002 N N   . GLN D 1 344 ? 38.761  38.025  47.108 1.00 68.08  ? 546 GLN D N   1 
ATOM   12003 C CA  . GLN D 1 344 ? 37.682  38.980  47.318 1.00 69.26  ? 546 GLN D CA  1 
ATOM   12004 C C   . GLN D 1 344 ? 37.469  39.827  46.071 1.00 69.29  ? 546 GLN D C   1 
ATOM   12005 O O   . GLN D 1 344 ? 38.400  40.464  45.569 1.00 68.73  ? 546 GLN D O   1 
ATOM   12006 C CB  . GLN D 1 344 ? 37.991  39.873  48.516 1.00 71.11  ? 546 GLN D CB  1 
ATOM   12007 C CG  . GLN D 1 344 ? 36.918  40.906  48.801 1.00 75.51  ? 546 GLN D CG  1 
ATOM   12008 C CD  . GLN D 1 344 ? 35.591  40.284  49.175 1.00 77.61  ? 546 GLN D CD  1 
ATOM   12009 O OE1 . GLN D 1 344 ? 34.686  40.183  48.349 1.00 79.97  ? 546 GLN D OE1 1 
ATOM   12010 N NE2 . GLN D 1 344 ? 35.465  39.864  50.428 1.00 77.52  ? 546 GLN D NE2 1 
ATOM   12011 N N   . GLY D 1 345 ? 36.233  39.839  45.579 1.00 64.81  ? 547 GLY D N   1 
ATOM   12012 C CA  . GLY D 1 345 ? 35.917  40.521  44.343 1.00 64.96  ? 547 GLY D CA  1 
ATOM   12013 C C   . GLY D 1 345 ? 36.380  39.819  43.089 1.00 65.33  ? 547 GLY D C   1 
ATOM   12014 O O   . GLY D 1 345 ? 36.864  40.486  42.169 1.00 65.92  ? 547 GLY D O   1 
ATOM   12015 N N   . THR D 1 346 ? 36.258  38.497  43.020 1.00 62.29  ? 548 THR D N   1 
ATOM   12016 C CA  . THR D 1 346 ? 36.667  37.761  41.834 1.00 61.95  ? 548 THR D CA  1 
ATOM   12017 C C   . THR D 1 346 ? 35.504  37.648  40.858 1.00 62.81  ? 548 THR D C   1 
ATOM   12018 O O   . THR D 1 346 ? 34.370  37.358  41.250 1.00 61.28  ? 548 THR D O   1 
ATOM   12019 C CB  . THR D 1 346 ? 37.170  36.366  42.210 1.00 61.25  ? 548 THR D CB  1 
ATOM   12020 O OG1 . THR D 1 346 ? 38.286  36.483  43.100 1.00 61.95  ? 548 THR D OG1 1 
ATOM   12021 C CG2 . THR D 1 346 ? 37.613  35.606  40.971 1.00 59.95  ? 548 THR D CG2 1 
ATOM   12022 N N   . GLY D 1 347 ? 35.792  37.886  39.583 1.00 57.65  ? 549 GLY D N   1 
ATOM   12023 C CA  . GLY D 1 347 ? 34.781  37.765  38.552 1.00 59.09  ? 549 GLY D CA  1 
ATOM   12024 C C   . GLY D 1 347 ? 34.238  36.352  38.446 1.00 60.64  ? 549 GLY D C   1 
ATOM   12025 O O   . GLY D 1 347 ? 34.796  35.382  38.956 1.00 59.35  ? 549 GLY D O   1 
ATOM   12026 N N   . ARG D 1 348 ? 33.100  36.247  37.769 1.00 50.39  ? 550 ARG D N   1 
ATOM   12027 C CA  . ARG D 1 348 ? 32.414  34.969  37.646 1.00 53.28  ? 550 ARG D CA  1 
ATOM   12028 C C   . ARG D 1 348 ? 32.987  34.077  36.552 1.00 53.83  ? 550 ARG D C   1 
ATOM   12029 O O   . ARG D 1 348 ? 33.134  32.869  36.771 1.00 53.38  ? 550 ARG D O   1 
ATOM   12030 C CB  . ARG D 1 348 ? 30.923  35.203  37.393 1.00 47.41  ? 550 ARG D CB  1 
ATOM   12031 C CG  . ARG D 1 348 ? 30.104  33.933  37.321 1.00 55.76  ? 550 ARG D CG  1 
ATOM   12032 C CD  . ARG D 1 348 ? 28.636  34.233  37.105 1.00 60.75  ? 550 ARG D CD  1 
ATOM   12033 N NE  . ARG D 1 348 ? 27.843  33.011  37.034 1.00 65.65  ? 550 ARG D NE  1 
ATOM   12034 C CZ  . ARG D 1 348 ? 27.661  32.305  35.923 1.00 69.01  ? 550 ARG D CZ  1 
ATOM   12035 N NH1 . ARG D 1 348 ? 28.219  32.701  34.787 1.00 69.15  ? 550 ARG D NH1 1 
ATOM   12036 N NH2 . ARG D 1 348 ? 26.923  31.205  35.948 1.00 70.72  ? 550 ARG D NH2 1 
ATOM   12037 N N   . ASP D 1 349 ? 33.326  34.632  35.388 1.00 53.25  ? 551 ASP D N   1 
ATOM   12038 C CA  . ASP D 1 349 ? 33.628  33.824  34.212 1.00 54.63  ? 551 ASP D CA  1 
ATOM   12039 C C   . ASP D 1 349 ? 35.019  34.124  33.676 1.00 53.38  ? 551 ASP D C   1 
ATOM   12040 O O   . ASP D 1 349 ? 35.365  35.286  33.450 1.00 53.60  ? 551 ASP D O   1 
ATOM   12041 C CB  . ASP D 1 349 ? 32.591  34.062  33.109 1.00 54.09  ? 551 ASP D CB  1 
ATOM   12042 C CG  . ASP D 1 349 ? 31.234  33.496  33.457 1.00 59.29  ? 551 ASP D CG  1 
ATOM   12043 O OD1 . ASP D 1 349 ? 31.160  32.656  34.376 1.00 62.11  ? 551 ASP D OD1 1 
ATOM   12044 O OD2 . ASP D 1 349 ? 30.239  33.895  32.817 1.00 61.10  ? 551 ASP D OD2 1 
ATOM   12045 N N   . ASN D 1 350 ? 35.801  33.062  33.467 1.00 53.81  ? 552 ASN D N   1 
ATOM   12046 C CA  . ASN D 1 350 ? 37.086  33.110  32.769 1.00 52.02  ? 552 ASN D CA  1 
ATOM   12047 C C   . ASN D 1 350 ? 38.043  34.120  33.405 1.00 50.01  ? 552 ASN D C   1 
ATOM   12048 O O   . ASN D 1 350 ? 38.687  34.924  32.729 1.00 49.36  ? 552 ASN D O   1 
ATOM   12049 C CB  . ASN D 1 350 ? 36.882  33.397  31.280 1.00 53.20  ? 552 ASN D CB  1 
ATOM   12050 C CG  . ASN D 1 350 ? 36.220  32.245  30.556 1.00 54.51  ? 552 ASN D CG  1 
ATOM   12051 O OD1 . ASN D 1 350 ? 36.282  31.102  31.002 1.00 53.71  ? 552 ASN D OD1 1 
ATOM   12052 N ND2 . ASN D 1 350 ? 35.580  32.540  29.434 1.00 56.17  ? 552 ASN D ND2 1 
ATOM   12053 N N   . VAL D 1 351 ? 38.131  34.058  34.723 1.00 54.80  ? 553 VAL D N   1 
ATOM   12054 C CA  . VAL D 1 351 ? 39.090  34.851  35.478 1.00 53.77  ? 553 VAL D CA  1 
ATOM   12055 C C   . VAL D 1 351 ? 40.457  34.198  35.358 1.00 54.19  ? 553 VAL D C   1 
ATOM   12056 O O   . VAL D 1 351 ? 40.573  32.993  35.107 1.00 53.52  ? 553 VAL D O   1 
ATOM   12057 C CB  . VAL D 1 351 ? 38.668  34.997  36.954 1.00 53.99  ? 553 VAL D CB  1 
ATOM   12058 C CG1 . VAL D 1 351 ? 37.332  35.701  37.039 1.00 56.08  ? 553 VAL D CG1 1 
ATOM   12059 C CG2 . VAL D 1 351 ? 38.612  33.643  37.633 1.00 52.62  ? 553 VAL D CG2 1 
ATOM   12060 N N   . ASP D 1 352 ? 41.505  34.996  35.539 1.00 58.81  ? 554 ASP D N   1 
ATOM   12061 C CA  . ASP D 1 352 ? 42.858  34.490  35.377 1.00 61.06  ? 554 ASP D CA  1 
ATOM   12062 C C   . ASP D 1 352 ? 43.273  33.654  36.588 1.00 59.83  ? 554 ASP D C   1 
ATOM   12063 O O   . ASP D 1 352 ? 42.538  33.516  37.570 1.00 60.25  ? 554 ASP D O   1 
ATOM   12064 C CB  . ASP D 1 352 ? 43.837  35.642  35.167 1.00 60.41  ? 554 ASP D CB  1 
ATOM   12065 C CG  . ASP D 1 352 ? 43.639  36.333  33.837 1.00 66.22  ? 554 ASP D CG  1 
ATOM   12066 O OD1 . ASP D 1 352 ? 42.955  35.759  32.966 1.00 68.77  ? 554 ASP D OD1 1 
ATOM   12067 O OD2 . ASP D 1 352 ? 44.171  37.449  33.662 1.00 70.17  ? 554 ASP D OD2 1 
ATOM   12068 N N   . ALA D 1 353 ? 44.486  33.102  36.512 1.00 61.12  ? 555 ALA D N   1 
ATOM   12069 C CA  . ALA D 1 353 ? 44.965  32.224  37.574 1.00 60.14  ? 555 ALA D CA  1 
ATOM   12070 C C   . ALA D 1 353 ? 45.330  33.000  38.832 1.00 60.21  ? 555 ALA D C   1 
ATOM   12071 O O   . ALA D 1 353 ? 45.196  32.473  39.942 1.00 59.71  ? 555 ALA D O   1 
ATOM   12072 C CB  . ALA D 1 353 ? 46.165  31.414  37.085 1.00 57.50  ? 555 ALA D CB  1 
ATOM   12073 N N   . ASP D 1 354 ? 45.796  34.241  38.687 1.00 65.29  ? 556 ASP D N   1 
ATOM   12074 C CA  . ASP D 1 354 ? 46.116  35.058  39.850 1.00 65.84  ? 556 ASP D CA  1 
ATOM   12075 C C   . ASP D 1 354 ? 44.881  35.663  40.504 1.00 63.87  ? 556 ASP D C   1 
ATOM   12076 O O   . ASP D 1 354 ? 45.009  36.302  41.554 1.00 63.00  ? 556 ASP D O   1 
ATOM   12077 C CB  . ASP D 1 354 ? 47.105  36.160  39.465 1.00 64.75  ? 556 ASP D CB  1 
ATOM   12078 C CG  . ASP D 1 354 ? 46.596  37.036  38.341 1.00 70.02  ? 556 ASP D CG  1 
ATOM   12079 O OD1 . ASP D 1 354 ? 45.547  36.705  37.752 1.00 73.49  ? 556 ASP D OD1 1 
ATOM   12080 O OD2 . ASP D 1 354 ? 47.247  38.059  38.048 1.00 73.04  ? 556 ASP D OD2 1 
ATOM   12081 N N   . LYS D 1 355 ? 43.701  35.493  39.910 1.00 62.79  ? 557 LYS D N   1 
ATOM   12082 C CA  . LYS D 1 355 ? 42.454  35.918  40.527 1.00 60.69  ? 557 LYS D CA  1 
ATOM   12083 C C   . LYS D 1 355 ? 41.879  34.879  41.479 1.00 58.20  ? 557 LYS D C   1 
ATOM   12084 O O   . LYS D 1 355 ? 40.934  35.190  42.212 1.00 56.57  ? 557 LYS D O   1 
ATOM   12085 C CB  . LYS D 1 355 ? 41.411  36.243  39.454 1.00 60.65  ? 557 LYS D CB  1 
ATOM   12086 C CG  . LYS D 1 355 ? 41.388  37.695  39.008 1.00 63.68  ? 557 LYS D CG  1 
ATOM   12087 C CD  . LYS D 1 355 ? 42.645  38.085  38.255 1.00 67.37  ? 557 LYS D CD  1 
ATOM   12088 C CE  . LYS D 1 355 ? 42.594  39.543  37.833 1.00 71.76  ? 557 LYS D CE  1 
ATOM   12089 N NZ  . LYS D 1 355 ? 43.812  39.949  37.082 1.00 68.90  ? 557 LYS D NZ  1 
ATOM   12090 N N   . VAL D 1 356 ? 42.421  33.663  41.487 1.00 53.30  ? 558 VAL D N   1 
ATOM   12091 C CA  . VAL D 1 356 ? 41.908  32.581  42.312 1.00 52.49  ? 558 VAL D CA  1 
ATOM   12092 C C   . VAL D 1 356 ? 43.030  32.073  43.203 1.00 52.34  ? 558 VAL D C   1 
ATOM   12093 O O   . VAL D 1 356 ? 44.211  32.353  42.986 1.00 52.34  ? 558 VAL D O   1 
ATOM   12094 C CB  . VAL D 1 356 ? 41.325  31.425  41.474 1.00 49.23  ? 558 VAL D CB  1 
ATOM   12095 C CG1 . VAL D 1 356 ? 40.127  31.896  40.665 1.00 52.78  ? 558 VAL D CG1 1 
ATOM   12096 C CG2 . VAL D 1 356 ? 42.396  30.835  40.574 1.00 49.25  ? 558 VAL D CG2 1 
ATOM   12097 N N   . MET D 1 357 ? 42.640  31.319  44.226 1.00 49.57  ? 559 MET D N   1 
ATOM   12098 C CA  . MET D 1 357 ? 43.569  30.694  45.158 1.00 49.84  ? 559 MET D CA  1 
ATOM   12099 C C   . MET D 1 357 ? 43.415  29.186  45.041 1.00 49.68  ? 559 MET D C   1 
ATOM   12100 O O   . MET D 1 357 ? 42.360  28.641  45.382 1.00 49.13  ? 559 MET D O   1 
ATOM   12101 C CB  . MET D 1 357 ? 43.297  31.156  46.590 1.00 51.47  ? 559 MET D CB  1 
ATOM   12102 C CG  . MET D 1 357 ? 43.540  32.637  46.816 1.00 55.70  ? 559 MET D CG  1 
ATOM   12103 S SD  . MET D 1 357 ? 43.212  33.143  48.512 1.00 60.15  ? 559 MET D SD  1 
ATOM   12104 C CE  . MET D 1 357 ? 41.423  33.113  48.526 1.00 59.85  ? 559 MET D CE  1 
ATOM   12105 N N   . ILE D 1 358 ? 44.452  28.520  44.551 1.00 45.58  ? 560 ILE D N   1 
ATOM   12106 C CA  . ILE D 1 358 ? 44.464  27.069  44.416 1.00 45.53  ? 560 ILE D CA  1 
ATOM   12107 C C   . ILE D 1 358 ? 45.122  26.497  45.661 1.00 47.58  ? 560 ILE D C   1 
ATOM   12108 O O   . ILE D 1 358 ? 46.315  26.712  45.901 1.00 47.57  ? 560 ILE D O   1 
ATOM   12109 C CB  . ILE D 1 358 ? 45.197  26.623  43.145 1.00 46.54  ? 560 ILE D CB  1 
ATOM   12110 C CG1 . ILE D 1 358 ? 44.423  27.058  41.903 1.00 45.07  ? 560 ILE D CG1 1 
ATOM   12111 C CG2 . ILE D 1 358 ? 45.397  25.120  43.147 1.00 45.53  ? 560 ILE D CG2 1 
ATOM   12112 C CD1 . ILE D 1 358 ? 45.186  26.858  40.623 1.00 43.23  ? 560 ILE D CD1 1 
ATOM   12113 N N   . THR D 1 359 ? 44.350  25.751  46.437 1.00 44.68  ? 561 THR D N   1 
ATOM   12114 C CA  . THR D 1 359 ? 44.882  25.117  47.624 1.00 47.73  ? 561 THR D CA  1 
ATOM   12115 C C   . THR D 1 359 ? 45.560  23.832  47.187 1.00 51.08  ? 561 THR D C   1 
ATOM   12116 O O   . THR D 1 359 ? 45.233  23.271  46.146 1.00 50.55  ? 561 THR D O   1 
ATOM   12117 C CB  . THR D 1 359 ? 43.787  24.791  48.646 1.00 46.73  ? 561 THR D CB  1 
ATOM   12118 O OG1 . THR D 1 359 ? 42.848  23.884  48.065 1.00 48.25  ? 561 THR D OG1 1 
ATOM   12119 C CG2 . THR D 1 359 ? 43.066  26.047  49.069 1.00 46.17  ? 561 THR D CG2 1 
ATOM   12120 N N   . ASN D 1 360 ? 46.518  23.378  47.980 1.00 50.03  ? 562 ASN D N   1 
ATOM   12121 C CA  . ASN D 1 360 ? 47.256  22.162  47.684 1.00 54.22  ? 562 ASN D CA  1 
ATOM   12122 C C   . ASN D 1 360 ? 47.367  21.347  48.955 1.00 55.84  ? 562 ASN D C   1 
ATOM   12123 O O   . ASN D 1 360 ? 47.192  21.879  50.046 1.00 57.10  ? 562 ASN D O   1 
ATOM   12124 C CB  . ASN D 1 360 ? 48.639  22.483  47.116 1.00 52.75  ? 562 ASN D CB  1 
ATOM   12125 C CG  . ASN D 1 360 ? 49.504  23.261  48.085 1.00 56.93  ? 562 ASN D CG  1 
ATOM   12126 O OD1 . ASN D 1 360 ? 49.325  23.181  49.296 1.00 61.25  ? 562 ASN D OD1 1 
ATOM   12127 N ND2 . ASN D 1 360 ? 50.454  24.017  47.552 1.00 59.05  ? 562 ASN D ND2 1 
ATOM   12128 N N   . GLU D 1 361 ? 47.660  20.061  48.834 1.00 53.99  ? 563 GLU D N   1 
ATOM   12129 C CA  . GLU D 1 361 ? 47.760  19.244  50.026 1.00 56.00  ? 563 GLU D CA  1 
ATOM   12130 C C   . GLU D 1 361 ? 49.100  18.525  50.066 1.00 54.90  ? 563 GLU D C   1 
ATOM   12131 O O   . GLU D 1 361 ? 49.180  17.307  49.939 1.00 56.54  ? 563 GLU D O   1 
ATOM   12132 C CB  . GLU D 1 361 ? 46.631  18.215  50.049 1.00 46.39  ? 563 GLU D CB  1 
ATOM   12133 C CG  . GLU D 1 361 ? 45.302  18.702  49.494 1.00 52.15  ? 563 GLU D CG  1 
ATOM   12134 C CD  . GLU D 1 361 ? 44.406  19.324  50.549 1.00 55.21  ? 563 GLU D CD  1 
ATOM   12135 O OE1 . GLU D 1 361 ? 44.635  19.085  51.753 1.00 55.38  ? 563 GLU D OE1 1 
ATOM   12136 O OE2 . GLU D 1 361 ? 43.461  20.046  50.169 1.00 57.68  ? 563 GLU D OE2 1 
ATOM   12137 N N   . GLU D 1 362 ? 50.152  19.313  50.242 1.00 58.17  ? 564 GLU D N   1 
ATOM   12138 C CA  . GLU D 1 362 ? 51.517  18.817  50.357 1.00 56.74  ? 564 GLU D CA  1 
ATOM   12139 C C   . GLU D 1 362 ? 51.728  18.006  51.637 1.00 54.65  ? 564 GLU D C   1 
ATOM   12140 O O   . GLU D 1 362 ? 52.491  17.054  51.659 1.00 54.28  ? 564 GLU D O   1 
ATOM   12141 C CB  . GLU D 1 362 ? 52.536  19.959  50.237 1.00 61.59  ? 564 GLU D CB  1 
ATOM   12142 C CG  . GLU D 1 362 ? 52.533  20.958  51.382 1.00 65.75  ? 564 GLU D CG  1 
ATOM   12143 C CD  . GLU D 1 362 ? 53.446  20.547  52.517 1.00 68.03  ? 564 GLU D CD  1 
ATOM   12144 O OE1 . GLU D 1 362 ? 54.134  19.517  52.375 1.00 68.77  ? 564 GLU D OE1 1 
ATOM   12145 O OE2 . GLU D 1 362 ? 53.460  21.237  53.557 1.00 69.19  ? 564 GLU D OE2 1 
ATOM   12146 N N   . GLU D 1 363 ? 51.035  18.391  52.700 1.00 58.46  ? 565 GLU D N   1 
ATOM   12147 C CA  . GLU D 1 363 ? 51.191  17.760  54.004 1.00 56.75  ? 565 GLU D CA  1 
ATOM   12148 C C   . GLU D 1 363 ? 50.861  16.280  54.014 1.00 52.99  ? 565 GLU D C   1 
ATOM   12149 O O   . GLU D 1 363 ? 51.513  15.504  54.703 1.00 52.85  ? 565 GLU D O   1 
ATOM   12150 C CB  . GLU D 1 363 ? 50.332  18.470  55.056 1.00 53.10  ? 565 GLU D CB  1 
ATOM   12151 C CG  . GLU D 1 363 ? 50.212  19.972  54.879 1.00 60.92  ? 565 GLU D CG  1 
ATOM   12152 C CD  . GLU D 1 363 ? 49.144  20.357  53.874 1.00 65.13  ? 565 GLU D CD  1 
ATOM   12153 O OE1 . GLU D 1 363 ? 48.261  19.518  53.592 1.00 65.30  ? 565 GLU D OE1 1 
ATOM   12154 O OE2 . GLU D 1 363 ? 49.185  21.497  53.367 1.00 67.99  ? 565 GLU D OE2 1 
ATOM   12155 N N   . ILE D 1 364 ? 49.854  15.892  53.244 1.00 55.17  ? 566 ILE D N   1 
ATOM   12156 C CA  . ILE D 1 364 ? 49.394  14.507  53.203 1.00 50.30  ? 566 ILE D CA  1 
ATOM   12157 C C   . ILE D 1 364 ? 50.206  13.559  52.325 1.00 49.00  ? 566 ILE D C   1 
ATOM   12158 O O   . ILE D 1 364 ? 49.874  12.387  52.232 1.00 48.29  ? 566 ILE D O   1 
ATOM   12159 C CB  . ILE D 1 364 ? 47.913  14.409  52.810 1.00 49.67  ? 566 ILE D CB  1 
ATOM   12160 C CG1 . ILE D 1 364 ? 47.715  14.815  51.354 1.00 48.04  ? 566 ILE D CG1 1 
ATOM   12161 C CG2 . ILE D 1 364 ? 47.066  15.261  53.736 1.00 49.23  ? 566 ILE D CG2 1 
ATOM   12162 C CD1 . ILE D 1 364 ? 46.278  14.734  50.892 1.00 46.10  ? 566 ILE D CD1 1 
ATOM   12163 N N   . LYS D 1 365 ? 51.258  14.054  51.681 1.00 50.55  ? 567 LYS D N   1 
ATOM   12164 C CA  . LYS D 1 365 ? 52.079  13.211  50.809 1.00 49.72  ? 567 LYS D CA  1 
ATOM   12165 C C   . LYS D 1 365 ? 52.734  12.035  51.543 1.00 48.74  ? 567 LYS D C   1 
ATOM   12166 O O   . LYS D 1 365 ? 52.910  10.972  50.971 1.00 48.62  ? 567 LYS D O   1 
ATOM   12167 C CB  . LYS D 1 365 ? 53.107  14.032  50.018 1.00 50.37  ? 567 LYS D CB  1 
ATOM   12168 C CG  . LYS D 1 365 ? 54.302  14.539  50.804 1.00 53.25  ? 567 LYS D CG  1 
ATOM   12169 C CD  . LYS D 1 365 ? 55.120  15.493  49.954 1.00 57.92  ? 567 LYS D CD  1 
ATOM   12170 C CE  . LYS D 1 365 ? 55.990  16.395  50.807 1.00 59.41  ? 567 LYS D CE  1 
ATOM   12171 N NZ  . LYS D 1 365 ? 56.602  17.468  49.980 1.00 61.87  ? 567 LYS D NZ  1 
ATOM   12172 N N   . THR D 1 366 ? 53.140  12.246  52.786 1.00 49.59  ? 568 THR D N   1 
ATOM   12173 C CA  . THR D 1 366 ? 53.752  11.199  53.590 1.00 47.96  ? 568 THR D CA  1 
ATOM   12174 C C   . THR D 1 366 ? 52.957  9.881   53.607 1.00 47.68  ? 568 THR D C   1 
ATOM   12175 O O   . THR D 1 366 ? 53.546  8.810   53.531 1.00 47.26  ? 568 THR D O   1 
ATOM   12176 C CB  . THR D 1 366 ? 53.973  11.692  55.028 1.00 47.73  ? 568 THR D CB  1 
ATOM   12177 O OG1 . THR D 1 366 ? 52.830  12.446  55.449 1.00 50.35  ? 568 THR D OG1 1 
ATOM   12178 C CG2 . THR D 1 366 ? 55.191  12.590  55.092 1.00 46.88  ? 568 THR D CG2 1 
ATOM   12179 N N   . THR D 1 367 ? 51.632  9.960   53.721 1.00 45.66  ? 569 THR D N   1 
ATOM   12180 C CA  . THR D 1 367 ? 50.767  8.791   53.735 1.00 45.43  ? 569 THR D CA  1 
ATOM   12181 C C   . THR D 1 367 ? 50.043  8.535   52.421 1.00 44.82  ? 569 THR D C   1 
ATOM   12182 O O   . THR D 1 367 ? 49.461  7.458   52.260 1.00 44.92  ? 569 THR D O   1 
ATOM   12183 C CB  . THR D 1 367 ? 49.717  8.917   54.849 1.00 47.36  ? 569 THR D CB  1 
ATOM   12184 O OG1 . THR D 1 367 ? 48.910  10.077  54.619 1.00 48.81  ? 569 THR D OG1 1 
ATOM   12185 C CG2 . THR D 1 367 ? 50.388  9.038   56.203 1.00 47.41  ? 569 THR D CG2 1 
ATOM   12186 N N   . ASN D 1 368 ? 50.069  9.473   51.479 1.00 44.49  ? 570 ASN D N   1 
ATOM   12187 C CA  . ASN D 1 368 ? 49.212  9.351   50.313 1.00 44.45  ? 570 ASN D CA  1 
ATOM   12188 C C   . ASN D 1 368 ? 50.014  9.511   49.029 1.00 45.41  ? 570 ASN D C   1 
ATOM   12189 O O   . ASN D 1 368 ? 50.976  10.284  48.983 1.00 46.84  ? 570 ASN D O   1 
ATOM   12190 C CB  . ASN D 1 368 ? 48.095  10.403  50.335 1.00 42.05  ? 570 ASN D CB  1 
ATOM   12191 C CG  . ASN D 1 368 ? 47.116  10.191  51.464 1.00 42.76  ? 570 ASN D CG  1 
ATOM   12192 O OD1 . ASN D 1 368 ? 47.018  9.100   52.012 1.00 43.35  ? 570 ASN D OD1 1 
ATOM   12193 N ND2 . ASN D 1 368 ? 46.372  11.231  51.805 1.00 43.47  ? 570 ASN D ND2 1 
ATOM   12194 N N   . PRO D 1 369 ? 49.636  8.804   47.968 1.00 47.47  ? 571 PRO D N   1 
ATOM   12195 C CA  . PRO D 1 369 ? 50.317  8.985   46.686 1.00 47.57  ? 571 PRO D CA  1 
ATOM   12196 C C   . PRO D 1 369 ? 49.965  10.324  46.061 1.00 47.92  ? 571 PRO D C   1 
ATOM   12197 O O   . PRO D 1 369 ? 48.987  10.977  46.429 1.00 48.03  ? 571 PRO D O   1 
ATOM   12198 C CB  . PRO D 1 369 ? 49.795  7.821   45.842 1.00 43.85  ? 571 PRO D CB  1 
ATOM   12199 C CG  . PRO D 1 369 ? 48.455  7.533   46.416 1.00 43.80  ? 571 PRO D CG  1 
ATOM   12200 C CD  . PRO D 1 369 ? 48.578  7.782   47.890 1.00 43.44  ? 571 PRO D CD  1 
ATOM   12201 N N   . VAL D 1 370 ? 50.789  10.735  45.100 1.00 50.28  ? 572 VAL D N   1 
ATOM   12202 C CA  . VAL D 1 370 ? 50.554  11.991  44.402 1.00 49.66  ? 572 VAL D CA  1 
ATOM   12203 C C   . VAL D 1 370 ? 49.375  11.831  43.452 1.00 50.08  ? 572 VAL D C   1 
ATOM   12204 O O   . VAL D 1 370 ? 49.234  10.805  42.773 1.00 49.87  ? 572 VAL D O   1 
ATOM   12205 C CB  . VAL D 1 370 ? 51.827  12.433  43.661 1.00 51.55  ? 572 VAL D CB  1 
ATOM   12206 C CG1 . VAL D 1 370 ? 51.570  13.684  42.840 1.00 51.25  ? 572 VAL D CG1 1 
ATOM   12207 C CG2 . VAL D 1 370 ? 52.945  12.673  44.652 1.00 51.14  ? 572 VAL D CG2 1 
ATOM   12208 N N   . ALA D 1 371 ? 48.511  12.848  43.408 1.00 49.10  ? 573 ALA D N   1 
ATOM   12209 C CA  . ALA D 1 371 ? 47.319  12.773  42.573 1.00 49.17  ? 573 ALA D CA  1 
ATOM   12210 C C   . ALA D 1 371 ? 47.662  12.658  41.094 1.00 49.77  ? 573 ALA D C   1 
ATOM   12211 O O   . ALA D 1 371 ? 46.883  12.088  40.325 1.00 49.13  ? 573 ALA D O   1 
ATOM   12212 C CB  . ALA D 1 371 ? 46.433  13.992  42.815 1.00 44.58  ? 573 ALA D CB  1 
ATOM   12213 N N   . THR D 1 372 ? 48.808  13.190  40.677 1.00 48.87  ? 574 THR D N   1 
ATOM   12214 C CA  . THR D 1 372 ? 49.210  13.185  39.278 1.00 49.36  ? 574 THR D CA  1 
ATOM   12215 C C   . THR D 1 372 ? 50.155  12.041  38.927 1.00 50.25  ? 574 THR D C   1 
ATOM   12216 O O   . THR D 1 372 ? 50.609  11.956  37.782 1.00 51.45  ? 574 THR D O   1 
ATOM   12217 C CB  . THR D 1 372 ? 49.852  14.524  38.914 1.00 52.59  ? 574 THR D CB  1 
ATOM   12218 O OG1 . THR D 1 372 ? 50.982  14.760  39.762 1.00 52.60  ? 574 THR D OG1 1 
ATOM   12219 C CG2 . THR D 1 372 ? 48.853  15.649  39.091 1.00 52.06  ? 574 THR D CG2 1 
ATOM   12220 N N   . GLU D 1 373 ? 50.462  11.165  39.877 1.00 49.22  ? 575 GLU D N   1 
ATOM   12221 C CA  . GLU D 1 373 ? 51.364  10.046  39.658 1.00 50.75  ? 575 GLU D CA  1 
ATOM   12222 C C   . GLU D 1 373 ? 50.600  8.734   39.774 1.00 49.31  ? 575 GLU D C   1 
ATOM   12223 O O   . GLU D 1 373 ? 49.554  8.658   40.422 1.00 49.01  ? 575 GLU D O   1 
ATOM   12224 C CB  . GLU D 1 373 ? 52.515  10.054  40.670 1.00 49.48  ? 575 GLU D CB  1 
ATOM   12225 C CG  . GLU D 1 373 ? 53.441  11.253  40.600 1.00 56.48  ? 575 GLU D CG  1 
ATOM   12226 C CD  . GLU D 1 373 ? 54.111  11.409  39.254 1.00 60.83  ? 575 GLU D CD  1 
ATOM   12227 O OE1 . GLU D 1 373 ? 54.464  10.383  38.636 1.00 63.37  ? 575 GLU D OE1 1 
ATOM   12228 O OE2 . GLU D 1 373 ? 54.298  12.564  38.821 1.00 63.48  ? 575 GLU D OE2 1 
ATOM   12229 N N   . SER D 1 374 ? 51.127  7.698   39.127 1.00 46.54  ? 576 SER D N   1 
ATOM   12230 C CA  . SER D 1 374 ? 50.550  6.370   39.274 1.00 46.44  ? 576 SER D CA  1 
ATOM   12231 C C   . SER D 1 374 ? 50.763  5.848   40.688 1.00 45.80  ? 576 SER D C   1 
ATOM   12232 O O   . SER D 1 374 ? 51.689  6.255   41.393 1.00 46.62  ? 576 SER D O   1 
ATOM   12233 C CB  . SER D 1 374 ? 51.163  5.395   38.271 1.00 39.18  ? 576 SER D CB  1 
ATOM   12234 O OG  . SER D 1 374 ? 50.819  5.735   36.943 1.00 42.58  ? 576 SER D OG  1 
ATOM   12235 N N   . TYR D 1 375 ? 49.884  4.934   41.102 1.00 42.50  ? 577 TYR D N   1 
ATOM   12236 C CA  . TYR D 1 375 ? 50.022  4.328   42.421 1.00 41.25  ? 577 TYR D CA  1 
ATOM   12237 C C   . TYR D 1 375 ? 51.239  3.418   42.478 1.00 41.66  ? 577 TYR D C   1 
ATOM   12238 O O   . TYR D 1 375 ? 51.942  3.370   43.493 1.00 41.31  ? 577 TYR D O   1 
ATOM   12239 C CB  . TYR D 1 375 ? 48.759  3.546   42.776 1.00 41.24  ? 577 TYR D CB  1 
ATOM   12240 C CG  . TYR D 1 375 ? 48.826  2.842   44.112 1.00 40.44  ? 577 TYR D CG  1 
ATOM   12241 C CD1 . TYR D 1 375 ? 48.607  3.534   45.292 1.00 40.51  ? 577 TYR D CD1 1 
ATOM   12242 C CD2 . TYR D 1 375 ? 49.115  1.489   44.192 1.00 39.47  ? 577 TYR D CD2 1 
ATOM   12243 C CE1 . TYR D 1 375 ? 48.671  2.897   46.513 1.00 40.40  ? 577 TYR D CE1 1 
ATOM   12244 C CE2 . TYR D 1 375 ? 49.181  0.846   45.407 1.00 38.91  ? 577 TYR D CE2 1 
ATOM   12245 C CZ  . TYR D 1 375 ? 48.959  1.555   46.562 1.00 39.46  ? 577 TYR D CZ  1 
ATOM   12246 O OH  . TYR D 1 375 ? 49.023  0.917   47.776 1.00 39.72  ? 577 TYR D OH  1 
ATOM   12247 N N   . GLY D 1 376 ? 51.505  2.693   41.397 1.00 42.48  ? 578 GLY D N   1 
ATOM   12248 C CA  . GLY D 1 376 ? 52.609  1.755   41.382 1.00 42.10  ? 578 GLY D CA  1 
ATOM   12249 C C   . GLY D 1 376 ? 52.559  0.901   40.132 1.00 42.59  ? 578 GLY D C   1 
ATOM   12250 O O   . GLY D 1 376 ? 51.965  1.289   39.125 1.00 42.38  ? 578 GLY D O   1 
ATOM   12251 N N   . GLN D 1 377 ? 53.190  -0.268  40.215 1.00 42.29  ? 579 GLN D N   1 
ATOM   12252 C CA  . GLN D 1 377 ? 53.278  -1.185  39.089 1.00 43.39  ? 579 GLN D CA  1 
ATOM   12253 C C   . GLN D 1 377 ? 52.889  -2.591  39.521 1.00 42.50  ? 579 GLN D C   1 
ATOM   12254 O O   . GLN D 1 377 ? 53.080  -2.983  40.674 1.00 42.42  ? 579 GLN D O   1 
ATOM   12255 C CB  . GLN D 1 377 ? 54.685  -1.194  38.487 1.00 39.45  ? 579 GLN D CB  1 
ATOM   12256 C CG  . GLN D 1 377 ? 55.072  0.115   37.828 1.00 45.78  ? 579 GLN D CG  1 
ATOM   12257 C CD  . GLN D 1 377 ? 56.480  0.098   37.279 1.00 51.07  ? 579 GLN D CD  1 
ATOM   12258 O OE1 . GLN D 1 377 ? 57.328  -0.667  37.736 1.00 54.26  ? 579 GLN D OE1 1 
ATOM   12259 N NE2 . GLN D 1 377 ? 56.739  0.945   36.293 1.00 52.53  ? 579 GLN D NE2 1 
ATOM   12260 N N   . VAL D 1 378 ? 52.334  -3.346  38.572 1.00 41.21  ? 580 VAL D N   1 
ATOM   12261 C CA  . VAL D 1 378 ? 51.938  -4.731  38.776 1.00 41.11  ? 580 VAL D CA  1 
ATOM   12262 C C   . VAL D 1 378 ? 52.545  -5.575  37.666 1.00 41.86  ? 580 VAL D C   1 
ATOM   12263 O O   . VAL D 1 378 ? 52.889  -5.078  36.594 1.00 41.59  ? 580 VAL D O   1 
ATOM   12264 C CB  . VAL D 1 378 ? 50.406  -4.911  38.795 1.00 40.82  ? 580 VAL D CB  1 
ATOM   12265 C CG1 . VAL D 1 378 ? 49.801  -4.197  39.973 1.00 41.25  ? 580 VAL D CG1 1 
ATOM   12266 C CG2 . VAL D 1 378 ? 49.802  -4.404  37.503 1.00 39.76  ? 580 VAL D CG2 1 
ATOM   12267 N N   . ALA D 1 379 ? 52.664  -6.872  37.933 1.00 41.29  ? 581 ALA D N   1 
ATOM   12268 C CA  . ALA D 1 379 ? 53.099  -7.815  36.914 1.00 42.73  ? 581 ALA D CA  1 
ATOM   12269 C C   . ALA D 1 379 ? 51.956  -8.076  35.942 1.00 43.74  ? 581 ALA D C   1 
ATOM   12270 O O   . ALA D 1 379 ? 50.843  -8.404  36.358 1.00 43.38  ? 581 ALA D O   1 
ATOM   12271 C CB  . ALA D 1 379 ? 53.562  -9.121  37.557 1.00 42.46  ? 581 ALA D CB  1 
ATOM   12272 N N   . THR D 1 380 ? 52.213  -7.887  34.652 1.00 41.84  ? 582 THR D N   1 
ATOM   12273 C CA  . THR D 1 380 ? 51.190  -8.082  33.634 1.00 42.50  ? 582 THR D CA  1 
ATOM   12274 C C   . THR D 1 380 ? 51.278  -9.421  32.911 1.00 43.76  ? 582 THR D C   1 
ATOM   12275 O O   . THR D 1 380 ? 50.446  -9.684  32.038 1.00 44.40  ? 582 THR D O   1 
ATOM   12276 C CB  . THR D 1 380 ? 51.235  -6.941  32.614 1.00 46.98  ? 582 THR D CB  1 
ATOM   12277 O OG1 . THR D 1 380 ? 52.537  -6.869  32.023 1.00 48.64  ? 582 THR D OG1 1 
ATOM   12278 C CG2 . THR D 1 380 ? 50.914  -5.624  33.290 1.00 44.82  ? 582 THR D CG2 1 
ATOM   12279 N N   . ASN D 1 381 ? 52.251  -10.270 33.232 1.00 45.78  ? 583 ASN D N   1 
ATOM   12280 C CA  . ASN D 1 381 ? 52.397  -11.536 32.521 1.00 46.66  ? 583 ASN D CA  1 
ATOM   12281 C C   . ASN D 1 381 ? 53.198  -12.507 33.382 1.00 47.93  ? 583 ASN D C   1 
ATOM   12282 O O   . ASN D 1 381 ? 53.606  -12.183 34.501 1.00 48.17  ? 583 ASN D O   1 
ATOM   12283 C CB  . ASN D 1 381 ? 53.068  -11.324 31.158 1.00 49.24  ? 583 ASN D CB  1 
ATOM   12284 C CG  . ASN D 1 381 ? 54.503  -10.846 31.280 1.00 49.52  ? 583 ASN D CG  1 
ATOM   12285 O OD1 . ASN D 1 381 ? 54.929  -10.373 32.332 1.00 50.96  ? 583 ASN D OD1 1 
ATOM   12286 N ND2 . ASN D 1 381 ? 55.262  -10.985 30.201 1.00 49.75  ? 583 ASN D ND2 1 
ATOM   12287 N N   . HIS D 1 382 ? 53.419  -13.707 32.849 1.00 50.55  ? 584 HIS D N   1 
ATOM   12288 C CA  . HIS D 1 382 ? 54.367  -14.663 33.407 1.00 51.19  ? 584 HIS D CA  1 
ATOM   12289 C C   . HIS D 1 382 ? 55.652  -14.608 32.596 1.00 50.83  ? 584 HIS D C   1 
ATOM   12290 O O   . HIS D 1 382 ? 55.615  -14.649 31.362 1.00 51.03  ? 584 HIS D O   1 
ATOM   12291 C CB  . HIS D 1 382 ? 53.812  -16.088 33.398 1.00 45.78  ? 584 HIS D CB  1 
ATOM   12292 C CG  . HIS D 1 382 ? 52.691  -16.313 34.360 1.00 49.14  ? 584 HIS D CG  1 
ATOM   12293 N ND1 . HIS D 1 382 ? 51.866  -17.414 34.292 1.00 50.68  ? 584 HIS D ND1 1 
ATOM   12294 C CD2 . HIS D 1 382 ? 52.273  -15.594 35.427 1.00 51.36  ? 584 HIS D CD2 1 
ATOM   12295 C CE1 . HIS D 1 382 ? 50.978  -17.356 35.267 1.00 51.91  ? 584 HIS D CE1 1 
ATOM   12296 N NE2 . HIS D 1 382 ? 51.203  -16.262 35.971 1.00 53.28  ? 584 HIS D NE2 1 
ATOM   12297 N N   . GLN D 1 383 ? 56.781  -14.514 33.286 1.00 57.28  ? 585 GLN D N   1 
ATOM   12298 C CA  . GLN D 1 383 ? 58.061  -14.625 32.614 1.00 56.44  ? 585 GLN D CA  1 
ATOM   12299 C C   . GLN D 1 383 ? 58.342  -16.078 32.249 1.00 56.72  ? 585 GLN D C   1 
ATOM   12300 O O   . GLN D 1 383 ? 57.776  -17.017 32.815 1.00 56.50  ? 585 GLN D O   1 
ATOM   12301 C CB  . GLN D 1 383 ? 59.184  -14.107 33.499 1.00 59.02  ? 585 GLN D CB  1 
ATOM   12302 C CG  . GLN D 1 383 ? 59.398  -14.979 34.708 1.00 57.24  ? 585 GLN D CG  1 
ATOM   12303 C CD  . GLN D 1 383 ? 60.545  -14.514 35.552 1.00 56.08  ? 585 GLN D CD  1 
ATOM   12304 O OE1 . GLN D 1 383 ? 60.970  -13.366 35.455 1.00 55.85  ? 585 GLN D OE1 1 
ATOM   12305 N NE2 . GLN D 1 383 ? 61.062  -15.405 36.387 1.00 55.49  ? 585 GLN D NE2 1 
ATOM   12306 N N   . SER D 1 384 ? 59.240  -16.252 31.293 1.00 61.35  ? 586 SER D N   1 
ATOM   12307 C CA  . SER D 1 384 ? 59.674  -17.568 30.847 1.00 61.95  ? 586 SER D CA  1 
ATOM   12308 C C   . SER D 1 384 ? 60.996  -17.371 30.124 1.00 62.44  ? 586 SER D C   1 
ATOM   12309 O O   . SER D 1 384 ? 61.513  -16.254 30.039 1.00 61.82  ? 586 SER D O   1 
ATOM   12310 C CB  . SER D 1 384 ? 58.628  -18.231 29.951 1.00 61.28  ? 586 SER D CB  1 
ATOM   12311 O OG  . SER D 1 384 ? 58.425  -17.484 28.765 1.00 60.75  ? 586 SER D OG  1 
ATOM   12312 N N   . ALA D 1 385 ? 61.545  -18.466 29.598 1.00 62.55  ? 587 ALA D N   1 
ATOM   12313 C CA  . ALA D 1 385 ? 62.738  -18.342 28.772 1.00 63.73  ? 587 ALA D CA  1 
ATOM   12314 C C   . ALA D 1 385 ? 62.463  -17.509 27.529 1.00 65.17  ? 587 ALA D C   1 
ATOM   12315 O O   . ALA D 1 385 ? 63.370  -16.852 27.005 1.00 65.25  ? 587 ALA D O   1 
ATOM   12316 C CB  . ALA D 1 385 ? 63.257  -19.726 28.386 1.00 64.99  ? 587 ALA D CB  1 
ATOM   12317 N N   . GLN D 1 386 ? 61.221  -17.520 27.045 1.00 65.67  ? 588 GLN D N   1 
ATOM   12318 C CA  . GLN D 1 386 ? 60.840  -16.801 25.839 1.00 67.77  ? 588 GLN D CA  1 
ATOM   12319 C C   . GLN D 1 386 ? 60.180  -15.453 26.105 1.00 67.76  ? 588 GLN D C   1 
ATOM   12320 O O   . GLN D 1 386 ? 59.808  -14.772 25.145 1.00 68.93  ? 588 GLN D O   1 
ATOM   12321 C CB  . GLN D 1 386 ? 59.892  -17.660 24.994 1.00 67.35  ? 588 GLN D CB  1 
ATOM   12322 C CG  . GLN D 1 386 ? 60.497  -18.963 24.495 1.00 67.35  ? 588 GLN D CG  1 
ATOM   12323 C CD  . GLN D 1 386 ? 60.408  -20.081 25.518 1.00 67.35  ? 588 GLN D CD  1 
ATOM   12324 O OE1 . GLN D 1 386 ? 59.891  -19.891 26.619 1.00 67.35  ? 588 GLN D OE1 1 
ATOM   12325 N NE2 . GLN D 1 386 ? 60.909  -21.255 25.157 1.00 67.35  ? 588 GLN D NE2 1 
ATOM   12326 N N   . ALA D 1 387 ? 60.018  -15.046 27.363 1.00 65.32  ? 589 ALA D N   1 
ATOM   12327 C CA  . ALA D 1 387 ? 59.255  -13.840 27.666 1.00 63.47  ? 589 ALA D CA  1 
ATOM   12328 C C   . ALA D 1 387 ? 59.926  -13.035 28.767 1.00 62.44  ? 589 ALA D C   1 
ATOM   12329 O O   . ALA D 1 387 ? 60.281  -13.583 29.814 1.00 62.85  ? 589 ALA D O   1 
ATOM   12330 C CB  . ALA D 1 387 ? 57.821  -14.188 28.078 1.00 60.47  ? 589 ALA D CB  1 
ATOM   12331 N N   . GLN D 1 388 ? 60.079  -11.734 28.532 1.00 62.04  ? 590 GLN D N   1 
ATOM   12332 C CA  . GLN D 1 388 ? 60.600  -10.828 29.543 1.00 61.97  ? 590 GLN D CA  1 
ATOM   12333 C C   . GLN D 1 388 ? 59.495  -10.394 30.501 1.00 60.89  ? 590 GLN D C   1 
ATOM   12334 O O   . GLN D 1 388 ? 58.326  -10.264 30.130 1.00 60.35  ? 590 GLN D O   1 
ATOM   12335 C CB  . GLN D 1 388 ? 61.229  -9.598  28.892 1.00 66.84  ? 590 GLN D CB  1 
ATOM   12336 C CG  . GLN D 1 388 ? 62.488  -9.883  28.105 1.00 66.84  ? 590 GLN D CG  1 
ATOM   12337 C CD  . GLN D 1 388 ? 63.028  -8.651  27.420 1.00 66.84  ? 590 GLN D CD  1 
ATOM   12338 O OE1 . GLN D 1 388 ? 62.286  -7.714  27.129 1.00 66.84  ? 590 GLN D OE1 1 
ATOM   12339 N NE2 . GLN D 1 388 ? 64.330  -8.640  27.163 1.00 66.84  ? 590 GLN D NE2 1 
ATOM   12340 N N   . ALA D 1 389 ? 59.885  -10.172 31.753 1.00 57.84  ? 591 ALA D N   1 
ATOM   12341 C CA  . ALA D 1 389 ? 58.939  -9.709  32.756 1.00 57.60  ? 591 ALA D CA  1 
ATOM   12342 C C   . ALA D 1 389 ? 58.363  -8.361  32.355 1.00 57.42  ? 591 ALA D C   1 
ATOM   12343 O O   . ALA D 1 389 ? 59.099  -7.406  32.091 1.00 57.07  ? 591 ALA D O   1 
ATOM   12344 C CB  . ALA D 1 389 ? 59.616  -9.603  34.121 1.00 55.34  ? 591 ALA D CB  1 
ATOM   12345 N N   . GLN D 1 390 ? 57.038  -8.283  32.311 1.00 50.56  ? 592 GLN D N   1 
ATOM   12346 C CA  . GLN D 1 390 ? 56.352  -7.065  31.914 1.00 51.06  ? 592 GLN D CA  1 
ATOM   12347 C C   . GLN D 1 390 ? 55.578  -6.501  33.092 1.00 50.86  ? 592 GLN D C   1 
ATOM   12348 O O   . GLN D 1 390 ? 55.119  -7.244  33.964 1.00 50.28  ? 592 GLN D O   1 
ATOM   12349 C CB  . GLN D 1 390 ? 55.406  -7.312  30.741 1.00 52.19  ? 592 GLN D CB  1 
ATOM   12350 C CG  . GLN D 1 390 ? 56.107  -7.653  29.446 1.00 52.19  ? 592 GLN D CG  1 
ATOM   12351 C CD  . GLN D 1 390 ? 55.134  -7.930  28.324 1.00 52.19  ? 592 GLN D CD  1 
ATOM   12352 O OE1 . GLN D 1 390 ? 53.986  -8.304  28.560 1.00 52.19  ? 592 GLN D OE1 1 
ATOM   12353 N NE2 . GLN D 1 390 ? 55.585  -7.742  27.091 1.00 52.19  ? 592 GLN D NE2 1 
ATOM   12354 N N   . THR D 1 391 ? 55.440  -5.181  33.108 1.00 48.85  ? 593 THR D N   1 
ATOM   12355 C CA  . THR D 1 391 ? 54.719  -4.468  34.147 1.00 49.13  ? 593 THR D CA  1 
ATOM   12356 C C   . THR D 1 391 ? 53.748  -3.496  33.498 1.00 47.60  ? 593 THR D C   1 
ATOM   12357 O O   . THR D 1 391 ? 53.776  -3.264  32.287 1.00 47.71  ? 593 THR D O   1 
ATOM   12358 C CB  . THR D 1 391 ? 55.665  -3.709  35.091 1.00 49.89  ? 593 THR D CB  1 
ATOM   12359 O OG1 . THR D 1 391 ? 56.458  -2.784  34.337 1.00 52.33  ? 593 THR D OG1 1 
ATOM   12360 C CG2 . THR D 1 391 ? 56.577  -4.669  35.836 1.00 49.39  ? 593 THR D CG2 1 
ATOM   12361 N N   . GLY D 1 392 ? 52.876  -2.933  34.323 1.00 43.28  ? 594 GLY D N   1 
ATOM   12362 C CA  . GLY D 1 392 ? 51.973  -1.900  33.862 1.00 41.36  ? 594 GLY D CA  1 
ATOM   12363 C C   . GLY D 1 392 ? 51.683  -0.941  34.992 1.00 40.32  ? 594 GLY D C   1 
ATOM   12364 O O   . GLY D 1 392 ? 51.808  -1.278  36.172 1.00 40.41  ? 594 GLY D O   1 
ATOM   12365 N N   . TRP D 1 393 ? 51.287  0.266   34.613 1.00 42.65  ? 595 TRP D N   1 
ATOM   12366 C CA  . TRP D 1 393 ? 51.040  1.322   35.577 1.00 41.97  ? 595 TRP D CA  1 
ATOM   12367 C C   . TRP D 1 393 ? 49.634  1.185   36.137 1.00 40.25  ? 595 TRP D C   1 
ATOM   12368 O O   . TRP D 1 393 ? 48.676  0.956   35.395 1.00 40.22  ? 595 TRP D O   1 
ATOM   12369 C CB  . TRP D 1 393 ? 51.220  2.695   34.931 1.00 39.09  ? 595 TRP D CB  1 
ATOM   12370 C CG  . TRP D 1 393 ? 52.617  2.958   34.472 1.00 42.89  ? 595 TRP D CG  1 
ATOM   12371 C CD1 . TRP D 1 393 ? 53.106  2.802   33.211 1.00 43.58  ? 595 TRP D CD1 1 
ATOM   12372 C CD2 . TRP D 1 393 ? 53.713  3.411   35.273 1.00 45.23  ? 595 TRP D CD2 1 
ATOM   12373 N NE1 . TRP D 1 393 ? 54.436  3.137   33.173 1.00 45.05  ? 595 TRP D NE1 1 
ATOM   12374 C CE2 . TRP D 1 393 ? 54.832  3.514   34.429 1.00 45.57  ? 595 TRP D CE2 1 
ATOM   12375 C CE3 . TRP D 1 393 ? 53.854  3.739   36.622 1.00 47.23  ? 595 TRP D CE3 1 
ATOM   12376 C CZ2 . TRP D 1 393 ? 56.077  3.931   34.889 1.00 46.34  ? 595 TRP D CZ2 1 
ATOM   12377 C CZ3 . TRP D 1 393 ? 55.089  4.156   37.077 1.00 48.66  ? 595 TRP D CZ3 1 
ATOM   12378 C CH2 . TRP D 1 393 ? 56.184  4.249   36.213 1.00 47.98  ? 595 TRP D CH2 1 
ATOM   12379 N N   . VAL D 1 394 ? 49.515  1.323   37.452 1.00 38.28  ? 596 VAL D N   1 
ATOM   12380 C CA  . VAL D 1 394 ? 48.219  1.297   38.114 1.00 36.65  ? 596 VAL D CA  1 
ATOM   12381 C C   . VAL D 1 394 ? 47.741  2.738   38.209 1.00 36.81  ? 596 VAL D C   1 
ATOM   12382 O O   . VAL D 1 394 ? 48.284  3.531   38.980 1.00 36.29  ? 596 VAL D O   1 
ATOM   12383 C CB  . VAL D 1 394 ? 48.307  0.651   39.500 1.00 36.63  ? 596 VAL D CB  1 
ATOM   12384 C CG1 . VAL D 1 394 ? 46.973  0.745   40.207 1.00 35.18  ? 596 VAL D CG1 1 
ATOM   12385 C CG2 . VAL D 1 394 ? 48.753  -0.790  39.382 1.00 34.56  ? 596 VAL D CG2 1 
ATOM   12386 N N   . GLN D 1 395 ? 46.718  3.078   37.429 1.00 33.98  ? 597 GLN D N   1 
ATOM   12387 C CA  . GLN D 1 395 ? 46.234  4.450   37.430 1.00 34.72  ? 597 GLN D CA  1 
ATOM   12388 C C   . GLN D 1 395 ? 45.315  4.718   38.609 1.00 35.05  ? 597 GLN D C   1 
ATOM   12389 O O   . GLN D 1 395 ? 45.411  5.775   39.239 1.00 35.97  ? 597 GLN D O   1 
ATOM   12390 C CB  . GLN D 1 395 ? 45.515  4.754   36.119 1.00 39.42  ? 597 GLN D CB  1 
ATOM   12391 C CG  . GLN D 1 395 ? 46.383  4.574   34.889 1.00 40.77  ? 597 GLN D CG  1 
ATOM   12392 C CD  . GLN D 1 395 ? 47.650  5.397   34.935 1.00 39.59  ? 597 GLN D CD  1 
ATOM   12393 O OE1 . GLN D 1 395 ? 47.655  6.526   35.416 1.00 41.02  ? 597 GLN D OE1 1 
ATOM   12394 N NE2 . GLN D 1 395 ? 48.735  4.833   34.424 1.00 39.14  ? 597 GLN D NE2 1 
ATOM   12395 N N   . ASN D 1 396 ? 44.430  3.778   38.919 1.00 33.56  ? 598 ASN D N   1 
ATOM   12396 C CA  . ASN D 1 396 ? 43.549  3.886   40.068 1.00 33.39  ? 598 ASN D CA  1 
ATOM   12397 C C   . ASN D 1 396 ? 43.642  2.615   40.894 1.00 33.01  ? 598 ASN D C   1 
ATOM   12398 O O   . ASN D 1 396 ? 43.737  1.514   40.348 1.00 34.21  ? 598 ASN D O   1 
ATOM   12399 C CB  . ASN D 1 396 ? 42.099  4.135   39.648 1.00 31.04  ? 598 ASN D CB  1 
ATOM   12400 C CG  . ASN D 1 396 ? 41.558  3.045   38.760 1.00 32.01  ? 598 ASN D CG  1 
ATOM   12401 O OD1 . ASN D 1 396 ? 42.309  2.304   38.130 1.00 32.81  ? 598 ASN D OD1 1 
ATOM   12402 N ND2 . ASN D 1 396 ? 40.245  2.919   38.731 1.00 31.58  ? 598 ASN D ND2 1 
ATOM   12403 N N   . GLN D 1 397 ? 43.623  2.775   42.213 1.00 34.84  ? 599 GLN D N   1 
ATOM   12404 C CA  . GLN D 1 397 ? 43.755  1.651   43.129 1.00 32.92  ? 599 GLN D CA  1 
ATOM   12405 C C   . GLN D 1 397 ? 42.698  1.768   44.211 1.00 32.87  ? 599 GLN D C   1 
ATOM   12406 O O   . GLN D 1 397 ? 42.706  2.731   44.983 1.00 33.41  ? 599 GLN D O   1 
ATOM   12407 C CB  . GLN D 1 397 ? 45.155  1.609   43.747 1.00 33.87  ? 599 GLN D CB  1 
ATOM   12408 C CG  . GLN D 1 397 ? 45.396  0.438   44.683 1.00 33.29  ? 599 GLN D CG  1 
ATOM   12409 C CD  . GLN D 1 397 ? 45.326  -0.899  43.983 1.00 33.62  ? 599 GLN D CD  1 
ATOM   12410 O OE1 . GLN D 1 397 ? 46.080  -1.160  43.050 1.00 35.76  ? 599 GLN D OE1 1 
ATOM   12411 N NE2 . GLN D 1 397 ? 44.421  -1.758  44.432 1.00 32.70  ? 599 GLN D NE2 1 
ATOM   12412 N N   . GLY D 1 398 ? 41.797  0.794   44.268 1.00 30.52  ? 600 GLY D N   1 
ATOM   12413 C CA  . GLY D 1 398 ? 40.846  0.711   45.350 1.00 29.10  ? 600 GLY D CA  1 
ATOM   12414 C C   . GLY D 1 398 ? 41.508  0.268   46.636 1.00 28.91  ? 600 GLY D C   1 
ATOM   12415 O O   . GLY D 1 398 ? 42.720  0.085   46.722 1.00 28.47  ? 600 GLY D O   1 
ATOM   12416 N N   . ILE D 1 399 ? 40.678  0.078   47.660 1.00 29.12  ? 601 ILE D N   1 
ATOM   12417 C CA  . ILE D 1 399 ? 41.195  -0.235  48.986 1.00 28.40  ? 601 ILE D CA  1 
ATOM   12418 C C   . ILE D 1 399 ? 41.839  -1.614  48.991 1.00 27.98  ? 601 ILE D C   1 
ATOM   12419 O O   . ILE D 1 399 ? 41.373  -2.542  48.323 1.00 28.65  ? 601 ILE D O   1 
ATOM   12420 C CB  . ILE D 1 399 ? 40.069  -0.123  50.028 1.00 27.99  ? 601 ILE D CB  1 
ATOM   12421 C CG1 . ILE D 1 399 ? 39.568  1.314   50.110 1.00 28.39  ? 601 ILE D CG1 1 
ATOM   12422 C CG2 . ILE D 1 399 ? 40.553  -0.549  51.377 1.00 29.45  ? 601 ILE D CG2 1 
ATOM   12423 C CD1 . ILE D 1 399 ? 40.637  2.290   50.535 1.00 27.25  ? 601 ILE D CD1 1 
ATOM   12424 N N   . LEU D 1 400 ? 42.936  -1.736  49.734 1.00 30.16  ? 602 LEU D N   1 
ATOM   12425 C CA  . LEU D 1 400 ? 43.689  -2.949  49.996 1.00 29.61  ? 602 LEU D CA  1 
ATOM   12426 C C   . LEU D 1 400 ? 43.966  -3.061  51.489 1.00 30.68  ? 602 LEU D C   1 
ATOM   12427 O O   . LEU D 1 400 ? 44.196  -2.045  52.151 1.00 30.35  ? 602 LEU D O   1 
ATOM   12428 C CB  . LEU D 1 400 ? 45.022  -2.953  49.238 1.00 30.95  ? 602 LEU D CB  1 
ATOM   12429 C CG  . LEU D 1 400 ? 44.984  -2.968  47.713 1.00 30.22  ? 602 LEU D CG  1 
ATOM   12430 C CD1 . LEU D 1 400 ? 46.380  -2.791  47.145 1.00 29.69  ? 602 LEU D CD1 1 
ATOM   12431 C CD2 . LEU D 1 400 ? 44.374  -4.260  47.219 1.00 29.18  ? 602 LEU D CD2 1 
ATOM   12432 N N   . PRO D 1 401 ? 43.934  -4.267  52.053 1.00 33.85  ? 603 PRO D N   1 
ATOM   12433 C CA  . PRO D 1 401 ? 44.295  -4.420  53.465 1.00 34.04  ? 603 PRO D CA  1 
ATOM   12434 C C   . PRO D 1 401 ? 45.719  -3.944  53.708 1.00 34.25  ? 603 PRO D C   1 
ATOM   12435 O O   . PRO D 1 401 ? 46.646  -4.309  52.983 1.00 34.66  ? 603 PRO D O   1 
ATOM   12436 C CB  . PRO D 1 401 ? 44.148  -5.925  53.706 1.00 29.77  ? 603 PRO D CB  1 
ATOM   12437 C CG  . PRO D 1 401 ? 43.164  -6.366  52.690 1.00 32.25  ? 603 PRO D CG  1 
ATOM   12438 C CD  . PRO D 1 401 ? 43.445  -5.528  51.477 1.00 30.91  ? 603 PRO D CD  1 
ATOM   12439 N N   . GLY D 1 402 ? 45.886  -3.119  54.735 1.00 36.90  ? 604 GLY D N   1 
ATOM   12440 C CA  . GLY D 1 402 ? 47.161  -2.511  55.027 1.00 35.87  ? 604 GLY D CA  1 
ATOM   12441 C C   . GLY D 1 402 ? 47.285  -1.057  54.636 1.00 35.72  ? 604 GLY D C   1 
ATOM   12442 O O   . GLY D 1 402 ? 48.267  -0.415  55.022 1.00 35.96  ? 604 GLY D O   1 
ATOM   12443 N N   . MET D 1 403 ? 46.332  -0.519  53.883 1.00 35.43  ? 605 MET D N   1 
ATOM   12444 C CA  . MET D 1 403 ? 46.375  0.882   53.503 1.00 34.11  ? 605 MET D CA  1 
ATOM   12445 C C   . MET D 1 403 ? 46.129  1.793   54.695 1.00 33.46  ? 605 MET D C   1 
ATOM   12446 O O   . MET D 1 403 ? 45.265  1.538   55.537 1.00 34.04  ? 605 MET D O   1 
ATOM   12447 C CB  . MET D 1 403 ? 45.349  1.187   52.414 1.00 31.01  ? 605 MET D CB  1 
ATOM   12448 C CG  . MET D 1 403 ? 45.743  0.714   51.042 1.00 31.76  ? 605 MET D CG  1 
ATOM   12449 S SD  . MET D 1 403 ? 44.500  1.140   49.821 1.00 34.43  ? 605 MET D SD  1 
ATOM   12450 C CE  . MET D 1 403 ? 45.345  0.633   48.332 1.00 34.71  ? 605 MET D CE  1 
ATOM   12451 N N   . VAL D 1 404 ? 46.908  2.870   54.758 1.00 35.80  ? 606 VAL D N   1 
ATOM   12452 C CA  . VAL D 1 404 ? 46.687  3.959   55.698 1.00 35.34  ? 606 VAL D CA  1 
ATOM   12453 C C   . VAL D 1 404 ? 46.730  5.261   54.912 1.00 35.44  ? 606 VAL D C   1 
ATOM   12454 O O   . VAL D 1 404 ? 47.500  5.403   53.958 1.00 37.67  ? 606 VAL D O   1 
ATOM   12455 C CB  . VAL D 1 404 ? 47.723  3.969   56.843 1.00 33.70  ? 606 VAL D CB  1 
ATOM   12456 C CG1 . VAL D 1 404 ? 47.592  2.721   57.693 1.00 37.44  ? 606 VAL D CG1 1 
ATOM   12457 C CG2 . VAL D 1 404 ? 49.127  4.084   56.294 1.00 32.78  ? 606 VAL D CG2 1 
ATOM   12458 N N   . TRP D 1 405 ? 45.886  6.212   55.304 1.00 37.01  ? 607 TRP D N   1 
ATOM   12459 C CA  . TRP D 1 405 ? 45.778  7.446   54.539 1.00 36.93  ? 607 TRP D CA  1 
ATOM   12460 C C   . TRP D 1 405 ? 45.296  8.570   55.441 1.00 37.67  ? 607 TRP D C   1 
ATOM   12461 O O   . TRP D 1 405 ? 44.807  8.343   56.549 1.00 37.33  ? 607 TRP D O   1 
ATOM   12462 C CB  . TRP D 1 405 ? 44.834  7.292   53.341 1.00 31.45  ? 607 TRP D CB  1 
ATOM   12463 C CG  . TRP D 1 405 ? 43.436  6.976   53.727 1.00 31.95  ? 607 TRP D CG  1 
ATOM   12464 C CD1 . TRP D 1 405 ? 42.443  7.866   53.993 1.00 32.87  ? 607 TRP D CD1 1 
ATOM   12465 C CD2 . TRP D 1 405 ? 42.863  5.676   53.881 1.00 31.92  ? 607 TRP D CD2 1 
ATOM   12466 N NE1 . TRP D 1 405 ? 41.288  7.203   54.317 1.00 32.39  ? 607 TRP D NE1 1 
ATOM   12467 C CE2 . TRP D 1 405 ? 41.519  5.855   54.255 1.00 32.80  ? 607 TRP D CE2 1 
ATOM   12468 C CE3 . TRP D 1 405 ? 43.358  4.378   53.746 1.00 31.24  ? 607 TRP D CE3 1 
ATOM   12469 C CZ2 . TRP D 1 405 ? 40.663  4.786   54.492 1.00 32.32  ? 607 TRP D CZ2 1 
ATOM   12470 C CZ3 . TRP D 1 405 ? 42.508  3.320   53.982 1.00 32.79  ? 607 TRP D CZ3 1 
ATOM   12471 C CH2 . TRP D 1 405 ? 41.176  3.529   54.351 1.00 32.59  ? 607 TRP D CH2 1 
ATOM   12472 N N   . GLN D 1 406 ? 45.448  9.790   54.939 1.00 39.63  ? 608 GLN D N   1 
ATOM   12473 C CA  . GLN D 1 406 ? 44.952  10.998  55.577 1.00 40.87  ? 608 GLN D CA  1 
ATOM   12474 C C   . GLN D 1 406 ? 43.756  11.547  54.812 1.00 41.33  ? 608 GLN D C   1 
ATOM   12475 O O   . GLN D 1 406 ? 43.627  11.360  53.600 1.00 40.52  ? 608 GLN D O   1 
ATOM   12476 C CB  . GLN D 1 406 ? 46.040  12.071  55.655 1.00 40.02  ? 608 GLN D CB  1 
ATOM   12477 C CG  . GLN D 1 406 ? 47.121  11.808  56.675 1.00 45.66  ? 608 GLN D CG  1 
ATOM   12478 C CD  . GLN D 1 406 ? 46.585  11.814  58.086 1.00 49.31  ? 608 GLN D CD  1 
ATOM   12479 O OE1 . GLN D 1 406 ? 45.735  12.630  58.433 1.00 52.59  ? 608 GLN D OE1 1 
ATOM   12480 N NE2 . GLN D 1 406 ? 47.077  10.904  58.909 1.00 45.59  ? 608 GLN D NE2 1 
ATOM   12481 N N   . ASP D 1 407 ? 42.872  12.218  55.541 1.00 39.89  ? 609 ASP D N   1 
ATOM   12482 C CA  . ASP D 1 407 ? 41.752  12.905  54.926 1.00 40.67  ? 609 ASP D CA  1 
ATOM   12483 C C   . ASP D 1 407 ? 42.205  14.268  54.410 1.00 39.76  ? 609 ASP D C   1 
ATOM   12484 O O   . ASP D 1 407 ? 43.356  14.677  54.575 1.00 38.31  ? 609 ASP D O   1 
ATOM   12485 C CB  . ASP D 1 407 ? 40.608  13.045  55.924 1.00 37.88  ? 609 ASP D CB  1 
ATOM   12486 C CG  . ASP D 1 407 ? 39.966  11.718  56.262 1.00 43.25  ? 609 ASP D CG  1 
ATOM   12487 O OD1 . ASP D 1 407 ? 40.150  10.752  55.493 1.00 44.25  ? 609 ASP D OD1 1 
ATOM   12488 O OD2 . ASP D 1 407 ? 39.289  11.638  57.308 1.00 45.29  ? 609 ASP D OD2 1 
ATOM   12489 N N   . ARG D 1 408 ? 41.284  14.987  53.781 1.00 42.16  ? 610 ARG D N   1 
ATOM   12490 C CA  . ARG D 1 408 ? 41.596  16.297  53.236 1.00 42.50  ? 610 ARG D CA  1 
ATOM   12491 C C   . ARG D 1 408 ? 41.526  17.357  54.330 1.00 42.52  ? 610 ARG D C   1 
ATOM   12492 O O   . ARG D 1 408 ? 40.688  17.296  55.234 1.00 41.96  ? 610 ARG D O   1 
ATOM   12493 C CB  . ARG D 1 408 ? 40.638  16.636  52.093 1.00 36.29  ? 610 ARG D CB  1 
ATOM   12494 C CG  . ARG D 1 408 ? 40.960  17.920  51.356 1.00 37.71  ? 610 ARG D CG  1 
ATOM   12495 C CD  . ARG D 1 408 ? 39.960  18.176  50.248 1.00 39.84  ? 610 ARG D CD  1 
ATOM   12496 N NE  . ARG D 1 408 ? 40.022  17.140  49.224 1.00 42.74  ? 610 ARG D NE  1 
ATOM   12497 C CZ  . ARG D 1 408 ? 40.868  17.154  48.201 1.00 44.02  ? 610 ARG D CZ  1 
ATOM   12498 N NH1 . ARG D 1 408 ? 41.723  18.155  48.059 1.00 44.79  ? 610 ARG D NH1 1 
ATOM   12499 N NH2 . ARG D 1 408 ? 40.856  16.168  47.317 1.00 45.03  ? 610 ARG D NH2 1 
ATOM   12500 N N   . ASP D 1 409 ? 42.429  18.329  54.245 1.00 43.46  ? 611 ASP D N   1 
ATOM   12501 C CA  . ASP D 1 409 ? 42.536  19.380  55.242 1.00 43.90  ? 611 ASP D CA  1 
ATOM   12502 C C   . ASP D 1 409 ? 41.307  20.286  55.190 1.00 43.65  ? 611 ASP D C   1 
ATOM   12503 O O   . ASP D 1 409 ? 40.597  20.358  54.185 1.00 43.45  ? 611 ASP D O   1 
ATOM   12504 C CB  . ASP D 1 409 ? 43.816  20.189  55.007 1.00 46.20  ? 611 ASP D CB  1 
ATOM   12505 C CG  . ASP D 1 409 ? 44.120  21.162  56.133 1.00 48.54  ? 611 ASP D CG  1 
ATOM   12506 O OD1 . ASP D 1 409 ? 43.385  21.166  57.141 1.00 51.09  ? 611 ASP D OD1 1 
ATOM   12507 O OD2 . ASP D 1 409 ? 45.106  21.921  56.008 1.00 47.58  ? 611 ASP D OD2 1 
ATOM   12508 N N   . VAL D 1 410 ? 41.052  20.971  56.296 1.00 43.13  ? 612 VAL D N   1 
ATOM   12509 C CA  . VAL D 1 410 ? 39.980  21.956  56.358 1.00 41.75  ? 612 VAL D CA  1 
ATOM   12510 C C   . VAL D 1 410 ? 40.609  23.337  56.336 1.00 40.58  ? 612 VAL D C   1 
ATOM   12511 O O   . VAL D 1 410 ? 41.723  23.547  56.825 1.00 39.82  ? 612 VAL D O   1 
ATOM   12512 C CB  . VAL D 1 410 ? 39.081  21.777  57.598 1.00 40.30  ? 612 VAL D CB  1 
ATOM   12513 C CG1 . VAL D 1 410 ? 38.415  20.411  57.582 1.00 39.66  ? 612 VAL D CG1 1 
ATOM   12514 C CG2 . VAL D 1 410 ? 39.866  22.001  58.875 1.00 43.11  ? 612 VAL D CG2 1 
ATOM   12515 N N   . TYR D 1 411 ? 39.896  24.288  55.746 1.00 40.88  ? 613 TYR D N   1 
ATOM   12516 C CA  . TYR D 1 411 ? 40.397  25.637  55.566 1.00 40.50  ? 613 TYR D CA  1 
ATOM   12517 C C   . TYR D 1 411 ? 39.445  26.637  56.203 1.00 40.17  ? 613 TYR D C   1 
ATOM   12518 O O   . TYR D 1 411 ? 38.281  26.334  56.477 1.00 41.53  ? 613 TYR D O   1 
ATOM   12519 C CB  . TYR D 1 411 ? 40.583  25.961  54.082 1.00 39.42  ? 613 TYR D CB  1 
ATOM   12520 C CG  . TYR D 1 411 ? 41.605  25.085  53.410 1.00 42.92  ? 613 TYR D CG  1 
ATOM   12521 C CD1 . TYR D 1 411 ? 42.949  25.419  53.430 1.00 44.32  ? 613 TYR D CD1 1 
ATOM   12522 C CD2 . TYR D 1 411 ? 41.229  23.922  52.759 1.00 43.99  ? 613 TYR D CD2 1 
ATOM   12523 C CE1 . TYR D 1 411 ? 43.890  24.618  52.821 1.00 46.38  ? 613 TYR D CE1 1 
ATOM   12524 C CE2 . TYR D 1 411 ? 42.163  23.113  52.146 1.00 47.49  ? 613 TYR D CE2 1 
ATOM   12525 C CZ  . TYR D 1 411 ? 43.493  23.467  52.181 1.00 47.97  ? 613 TYR D CZ  1 
ATOM   12526 O OH  . TYR D 1 411 ? 44.433  22.668  51.573 1.00 49.93  ? 613 TYR D OH  1 
ATOM   12527 N N   . LEU D 1 412 ? 39.965  27.841  56.439 1.00 39.32  ? 614 LEU D N   1 
ATOM   12528 C CA  . LEU D 1 412 ? 39.138  28.909  56.983 1.00 38.78  ? 614 LEU D CA  1 
ATOM   12529 C C   . LEU D 1 412 ? 37.951  29.188  56.071 1.00 39.87  ? 614 LEU D C   1 
ATOM   12530 O O   . LEU D 1 412 ? 36.850  29.491  56.544 1.00 41.16  ? 614 LEU D O   1 
ATOM   12531 C CB  . LEU D 1 412 ? 39.982  30.169  57.168 1.00 40.58  ? 614 LEU D CB  1 
ATOM   12532 C CG  . LEU D 1 412 ? 39.416  31.281  58.046 1.00 40.32  ? 614 LEU D CG  1 
ATOM   12533 C CD1 . LEU D 1 412 ? 38.654  30.669  59.204 1.00 40.48  ? 614 LEU D CD1 1 
ATOM   12534 C CD2 . LEU D 1 412 ? 40.536  32.157  58.566 1.00 38.84  ? 614 LEU D CD2 1 
ATOM   12535 N N   . GLN D 1 413 ? 38.160  29.084  54.758 1.00 38.93  ? 615 GLN D N   1 
ATOM   12536 C CA  . GLN D 1 413 ? 37.121  29.289  53.760 1.00 38.78  ? 615 GLN D CA  1 
ATOM   12537 C C   . GLN D 1 413 ? 36.340  28.022  53.431 1.00 38.35  ? 615 GLN D C   1 
ATOM   12538 O O   . GLN D 1 413 ? 35.295  28.111  52.780 1.00 38.94  ? 615 GLN D O   1 
ATOM   12539 C CB  . GLN D 1 413 ? 37.734  29.831  52.464 1.00 35.95  ? 615 GLN D CB  1 
ATOM   12540 C CG  . GLN D 1 413 ? 38.426  31.168  52.600 1.00 41.35  ? 615 GLN D CG  1 
ATOM   12541 C CD  . GLN D 1 413 ? 39.858  31.028  53.063 1.00 44.24  ? 615 GLN D CD  1 
ATOM   12542 O OE1 . GLN D 1 413 ? 40.343  29.919  53.282 1.00 42.99  ? 615 GLN D OE1 1 
ATOM   12543 N NE2 . GLN D 1 413 ? 40.547  32.152  53.209 1.00 46.83  ? 615 GLN D NE2 1 
ATOM   12544 N N   . GLY D 1 414 ? 36.816  26.856  53.853 1.00 38.29  ? 616 GLY D N   1 
ATOM   12545 C CA  . GLY D 1 414 ? 36.221  25.606  53.446 1.00 36.65  ? 616 GLY D CA  1 
ATOM   12546 C C   . GLY D 1 414 ? 34.997  25.227  54.253 1.00 35.61  ? 616 GLY D C   1 
ATOM   12547 O O   . GLY D 1 414 ? 34.671  25.853  55.265 1.00 35.35  ? 616 GLY D O   1 
ATOM   12548 N N   . PRO D 1 415 ? 34.294  24.187  53.813 1.00 33.66  ? 617 PRO D N   1 
ATOM   12549 C CA  . PRO D 1 415 ? 33.102  23.742  54.537 1.00 33.85  ? 617 PRO D CA  1 
ATOM   12550 C C   . PRO D 1 415 ? 33.460  23.028  55.831 1.00 34.22  ? 617 PRO D C   1 
ATOM   12551 O O   . PRO D 1 415 ? 34.582  22.562  56.030 1.00 34.26  ? 617 PRO D O   1 
ATOM   12552 C CB  . PRO D 1 415 ? 32.424  22.793  53.548 1.00 32.47  ? 617 PRO D CB  1 
ATOM   12553 C CG  . PRO D 1 415 ? 33.541  22.266  52.729 1.00 33.19  ? 617 PRO D CG  1 
ATOM   12554 C CD  . PRO D 1 415 ? 34.529  23.390  52.598 1.00 31.80  ? 617 PRO D CD  1 
ATOM   12555 N N   . ILE D 1 416 ? 32.476  22.948  56.725 1.00 35.48  ? 618 ILE D N   1 
ATOM   12556 C CA  . ILE D 1 416 ? 32.691  22.325  58.026 1.00 33.71  ? 618 ILE D CA  1 
ATOM   12557 C C   . ILE D 1 416 ? 32.246  20.870  57.993 1.00 34.54  ? 618 ILE D C   1 
ATOM   12558 O O   . ILE D 1 416 ? 33.058  19.964  58.194 1.00 35.01  ? 618 ILE D O   1 
ATOM   12559 C CB  . ILE D 1 416 ? 31.971  23.085  59.150 1.00 37.30  ? 618 ILE D CB  1 
ATOM   12560 C CG1 . ILE D 1 416 ? 32.522  24.499  59.279 1.00 36.54  ? 618 ILE D CG1 1 
ATOM   12561 C CG2 . ILE D 1 416 ? 32.168  22.370  60.467 1.00 33.77  ? 618 ILE D CG2 1 
ATOM   12562 C CD1 . ILE D 1 416 ? 31.728  25.355  60.227 1.00 35.10  ? 618 ILE D CD1 1 
ATOM   12563 N N   . TRP D 1 417 ? 30.958  20.631  57.757 1.00 32.48  ? 619 TRP D N   1 
ATOM   12564 C CA  . TRP D 1 417 ? 30.414  19.282  57.778 1.00 32.74  ? 619 TRP D CA  1 
ATOM   12565 C C   . TRP D 1 417 ? 29.680  18.982  56.478 1.00 33.31  ? 619 TRP D C   1 
ATOM   12566 O O   . TRP D 1 417 ? 29.410  19.866  55.664 1.00 32.85  ? 619 TRP D O   1 
ATOM   12567 C CB  . TRP D 1 417 ? 29.456  19.064  58.960 1.00 30.87  ? 619 TRP D CB  1 
ATOM   12568 C CG  . TRP D 1 417 ? 28.180  19.853  58.886 1.00 32.15  ? 619 TRP D CG  1 
ATOM   12569 C CD1 . TRP D 1 417 ? 27.044  19.506  58.213 1.00 33.46  ? 619 TRP D CD1 1 
ATOM   12570 C CD2 . TRP D 1 417 ? 27.886  21.083  59.555 1.00 32.17  ? 619 TRP D CD2 1 
ATOM   12571 N NE1 . TRP D 1 417 ? 26.077  20.460  58.389 1.00 34.15  ? 619 TRP D NE1 1 
ATOM   12572 C CE2 . TRP D 1 417 ? 26.567  21.438  59.214 1.00 33.25  ? 619 TRP D CE2 1 
ATOM   12573 C CE3 . TRP D 1 417 ? 28.613  21.927  60.397 1.00 30.82  ? 619 TRP D CE3 1 
ATOM   12574 C CZ2 . TRP D 1 417 ? 25.963  22.599  59.683 1.00 33.76  ? 619 TRP D CZ2 1 
ATOM   12575 C CZ3 . TRP D 1 417 ? 28.011  23.076  60.863 1.00 32.29  ? 619 TRP D CZ3 1 
ATOM   12576 C CH2 . TRP D 1 417 ? 26.700  23.400  60.506 1.00 33.83  ? 619 TRP D CH2 1 
ATOM   12577 N N   . ALA D 1 418 ? 29.375  17.701  56.290 1.00 28.48  ? 620 ALA D N   1 
ATOM   12578 C CA  . ALA D 1 418 ? 28.511  17.251  55.211 1.00 29.66  ? 620 ALA D CA  1 
ATOM   12579 C C   . ALA D 1 418 ? 27.566  16.191  55.750 1.00 30.64  ? 620 ALA D C   1 
ATOM   12580 O O   . ALA D 1 418 ? 27.772  15.644  56.834 1.00 30.50  ? 620 ALA D O   1 
ATOM   12581 C CB  . ALA D 1 418 ? 29.308  16.687  54.036 1.00 27.99  ? 620 ALA D CB  1 
ATOM   12582 N N   . LYS D 1 419 ? 26.526  15.899  54.977 1.00 23.40  ? 621 LYS D N   1 
ATOM   12583 C CA  . LYS D 1 419 ? 25.548  14.890  55.360 1.00 23.98  ? 621 LYS D CA  1 
ATOM   12584 C C   . LYS D 1 419 ? 25.863  13.578  54.655 1.00 24.84  ? 621 LYS D C   1 
ATOM   12585 O O   . LYS D 1 419 ? 26.067  13.553  53.437 1.00 24.87  ? 621 LYS D O   1 
ATOM   12586 C CB  . LYS D 1 419 ? 24.129  15.339  55.025 1.00 20.93  ? 621 LYS D CB  1 
ATOM   12587 C CG  . LYS D 1 419 ? 23.084  14.325  55.438 1.00 22.30  ? 621 LYS D CG  1 
ATOM   12588 C CD  . LYS D 1 419 ? 21.682  14.841  55.232 1.00 24.34  ? 621 LYS D CD  1 
ATOM   12589 C CE  . LYS D 1 419 ? 20.663  13.784  55.599 1.00 27.25  ? 621 LYS D CE  1 
ATOM   12590 N NZ  . LYS D 1 419 ? 20.670  12.663  54.625 1.00 29.94  ? 621 LYS D NZ  1 
ATOM   12591 N N   . ILE D 1 420 ? 25.899  12.496  55.418 1.00 21.28  ? 622 ILE D N   1 
ATOM   12592 C CA  . ILE D 1 420 ? 26.125  11.171  54.833 1.00 21.79  ? 622 ILE D CA  1 
ATOM   12593 C C   . ILE D 1 420 ? 24.829  10.689  54.193 1.00 23.71  ? 622 ILE D C   1 
ATOM   12594 O O   . ILE D 1 420 ? 23.804  10.582  54.889 1.00 24.53  ? 622 ILE D O   1 
ATOM   12595 C CB  . ILE D 1 420 ? 26.599  10.195  55.906 1.00 24.74  ? 622 ILE D CB  1 
ATOM   12596 C CG1 . ILE D 1 420 ? 27.927  10.659  56.496 1.00 23.57  ? 622 ILE D CG1 1 
ATOM   12597 C CG2 . ILE D 1 420 ? 26.751  8.808   55.326 1.00 24.73  ? 622 ILE D CG2 1 
ATOM   12598 C CD1 . ILE D 1 420 ? 28.311  9.933   57.754 1.00 22.36  ? 622 ILE D CD1 1 
ATOM   12599 N N   . PRO D 1 421 ? 24.810  10.406  52.891 1.00 17.98  ? 623 PRO D N   1 
ATOM   12600 C CA  . PRO D 1 421 ? 23.578  9.922   52.265 1.00 18.91  ? 623 PRO D CA  1 
ATOM   12601 C C   . PRO D 1 421 ? 23.100  8.645   52.934 1.00 20.93  ? 623 PRO D C   1 
ATOM   12602 O O   . PRO D 1 421 ? 23.888  7.878   53.490 1.00 21.58  ? 623 PRO D O   1 
ATOM   12603 C CB  . PRO D 1 421 ? 23.997  9.669   50.814 1.00 18.96  ? 623 PRO D CB  1 
ATOM   12604 C CG  . PRO D 1 421 ? 25.146  10.575  50.603 1.00 18.92  ? 623 PRO D CG  1 
ATOM   12605 C CD  . PRO D 1 421 ? 25.885  10.585  51.904 1.00 18.43  ? 623 PRO D CD  1 
ATOM   12606 N N   . HIS D 1 422 ? 21.795  8.415   52.872 1.00 19.15  ? 624 HIS D N   1 
ATOM   12607 C CA  . HIS D 1 422 ? 21.199  7.276   53.555 1.00 20.59  ? 624 HIS D CA  1 
ATOM   12608 C C   . HIS D 1 422 ? 21.184  6.111   52.578 1.00 19.26  ? 624 HIS D C   1 
ATOM   12609 O O   . HIS D 1 422 ? 20.392  6.092   51.632 1.00 18.66  ? 624 HIS D O   1 
ATOM   12610 C CB  . HIS D 1 422 ? 19.790  7.610   54.035 1.00 18.45  ? 624 HIS D CB  1 
ATOM   12611 C CG  . HIS D 1 422 ? 19.177  6.545   54.885 1.00 23.52  ? 624 HIS D CG  1 
ATOM   12612 N ND1 . HIS D 1 422 ? 19.653  6.231   56.139 1.00 26.43  ? 624 HIS D ND1 1 
ATOM   12613 C CD2 . HIS D 1 422 ? 18.148  5.699   54.651 1.00 25.74  ? 624 HIS D CD2 1 
ATOM   12614 C CE1 . HIS D 1 422 ? 18.929  5.252   56.649 1.00 27.98  ? 624 HIS D CE1 1 
ATOM   12615 N NE2 . HIS D 1 422 ? 18.009  4.910   55.766 1.00 28.30  ? 624 HIS D NE2 1 
ATOM   12616 N N   . THR D 1 423 ? 22.046  5.130   52.821 1.00 18.74  ? 625 THR D N   1 
ATOM   12617 C CA  . THR D 1 423 ? 22.261  4.037   51.888 1.00 18.88  ? 625 THR D CA  1 
ATOM   12618 C C   . THR D 1 423 ? 22.513  2.762   52.674 1.00 19.04  ? 625 THR D C   1 
ATOM   12619 O O   . THR D 1 423 ? 22.736  2.785   53.885 1.00 18.79  ? 625 THR D O   1 
ATOM   12620 C CB  . THR D 1 423 ? 23.434  4.308   50.937 1.00 17.90  ? 625 THR D CB  1 
ATOM   12621 O OG1 . THR D 1 423 ? 24.612  4.596   51.699 1.00 17.41  ? 625 THR D OG1 1 
ATOM   12622 C CG2 . THR D 1 423 ? 23.136  5.461   49.995 1.00 16.87  ? 625 THR D CG2 1 
ATOM   12623 N N   . ASP D 1 424 ? 22.469  1.638   51.959 1.00 19.06  ? 626 ASP D N   1 
ATOM   12624 C CA  . ASP D 1 424 ? 22.723  0.352   52.591 1.00 19.44  ? 626 ASP D CA  1 
ATOM   12625 C C   . ASP D 1 424 ? 24.168  0.245   53.053 1.00 18.39  ? 626 ASP D C   1 
ATOM   12626 O O   . ASP D 1 424 ? 24.467  -0.434  54.041 1.00 19.33  ? 626 ASP D O   1 
ATOM   12627 C CB  . ASP D 1 424 ? 22.380  -0.777  51.625 1.00 19.68  ? 626 ASP D CB  1 
ATOM   12628 C CG  . ASP D 1 424 ? 20.904  -0.868  51.352 1.00 23.59  ? 626 ASP D CG  1 
ATOM   12629 O OD1 . ASP D 1 424 ? 20.138  -0.249  52.115 1.00 27.42  ? 626 ASP D OD1 1 
ATOM   12630 O OD2 . ASP D 1 424 ? 20.508  -1.552  50.387 1.00 25.75  ? 626 ASP D OD2 1 
ATOM   12631 N N   . GLY D 1 425 ? 25.080  0.912   52.355 1.00 19.35  ? 627 GLY D N   1 
ATOM   12632 C CA  . GLY D 1 425 ? 26.483  0.832   52.710 1.00 16.85  ? 627 GLY D CA  1 
ATOM   12633 C C   . GLY D 1 425 ? 27.260  2.050   52.268 1.00 16.17  ? 627 GLY D C   1 
ATOM   12634 O O   . GLY D 1 425 ? 26.872  2.769   51.343 1.00 16.28  ? 627 GLY D O   1 
ATOM   12635 N N   . ASN D 1 426 ? 28.373  2.272   52.960 1.00 19.53  ? 628 ASN D N   1 
ATOM   12636 C CA  . ASN D 1 426 ? 29.319  3.326   52.639 1.00 19.15  ? 628 ASN D CA  1 
ATOM   12637 C C   . ASN D 1 426 ? 30.666  2.945   53.230 1.00 18.56  ? 628 ASN D C   1 
ATOM   12638 O O   . ASN D 1 426 ? 30.756  2.070   54.093 1.00 17.90  ? 628 ASN D O   1 
ATOM   12639 C CB  . ASN D 1 426 ? 28.838  4.691   53.151 1.00 20.35  ? 628 ASN D CB  1 
ATOM   12640 C CG  . ASN D 1 426 ? 28.597  4.713   54.652 1.00 19.75  ? 628 ASN D CG  1 
ATOM   12641 O OD1 . ASN D 1 426 ? 29.292  4.058   55.424 1.00 18.08  ? 628 ASN D OD1 1 
ATOM   12642 N ND2 . ASN D 1 426 ? 27.592  5.471   55.069 1.00 20.66  ? 628 ASN D ND2 1 
ATOM   12643 N N   . PHE D 1 427 ? 31.719  3.600   52.752 1.00 22.89  ? 629 PHE D N   1 
ATOM   12644 C CA  . PHE D 1 427 ? 33.053  3.376   53.289 1.00 22.48  ? 629 PHE D CA  1 
ATOM   12645 C C   . PHE D 1 427 ? 33.731  4.708   53.550 1.00 23.98  ? 629 PHE D C   1 
ATOM   12646 O O   . PHE D 1 427 ? 33.726  5.589   52.686 1.00 23.96  ? 629 PHE D O   1 
ATOM   12647 C CB  . PHE D 1 427 ? 33.909  2.534   52.348 1.00 24.52  ? 629 PHE D CB  1 
ATOM   12648 C CG  . PHE D 1 427 ? 35.304  2.319   52.846 1.00 24.95  ? 629 PHE D CG  1 
ATOM   12649 C CD1 . PHE D 1 427 ? 35.561  1.385   53.831 1.00 23.33  ? 629 PHE D CD1 1 
ATOM   12650 C CD2 . PHE D 1 427 ? 36.360  3.051   52.336 1.00 24.64  ? 629 PHE D CD2 1 
ATOM   12651 C CE1 . PHE D 1 427 ? 36.843  1.187   54.298 1.00 23.25  ? 629 PHE D CE1 1 
ATOM   12652 C CE2 . PHE D 1 427 ? 37.643  2.854   52.797 1.00 24.73  ? 629 PHE D CE2 1 
ATOM   12653 C CZ  . PHE D 1 427 ? 37.884  1.921   53.779 1.00 24.17  ? 629 PHE D CZ  1 
ATOM   12654 N N   . HIS D 1 428 ? 34.331  4.831   54.735 1.00 24.89  ? 630 HIS D N   1 
ATOM   12655 C CA  . HIS D 1 428 ? 35.018  6.021   55.217 1.00 26.00  ? 630 HIS D CA  1 
ATOM   12656 C C   . HIS D 1 428 ? 34.151  7.230   54.899 1.00 26.53  ? 630 HIS D C   1 
ATOM   12657 O O   . HIS D 1 428 ? 34.492  8.035   54.024 1.00 27.13  ? 630 HIS D O   1 
ATOM   12658 C CB  . HIS D 1 428 ? 36.404  6.145   54.586 1.00 29.68  ? 630 HIS D CB  1 
ATOM   12659 C CG  . HIS D 1 428 ? 37.290  7.150   55.256 1.00 31.12  ? 630 HIS D CG  1 
ATOM   12660 N ND1 . HIS D 1 428 ? 37.707  7.017   56.563 1.00 31.71  ? 630 HIS D ND1 1 
ATOM   12661 C CD2 . HIS D 1 428 ? 37.852  8.294   54.798 1.00 31.38  ? 630 HIS D CD2 1 
ATOM   12662 C CE1 . HIS D 1 428 ? 38.480  8.038   56.883 1.00 32.20  ? 630 HIS D CE1 1 
ATOM   12663 N NE2 . HIS D 1 428 ? 38.585  8.827   55.830 1.00 32.00  ? 630 HIS D NE2 1 
ATOM   12664 N N   . PRO D 1 429 ? 33.024  7.380   55.589 1.00 28.84  ? 631 PRO D N   1 
ATOM   12665 C CA  . PRO D 1 429 ? 32.009  8.363   55.187 1.00 28.46  ? 631 PRO D CA  1 
ATOM   12666 C C   . PRO D 1 429 ? 32.482  9.809   55.171 1.00 28.44  ? 631 PRO D C   1 
ATOM   12667 O O   . PRO D 1 429 ? 31.736  10.683  54.721 1.00 29.77  ? 631 PRO D O   1 
ATOM   12668 C CB  . PRO D 1 429 ? 30.897  8.145   56.218 1.00 29.17  ? 631 PRO D CB  1 
ATOM   12669 C CG  . PRO D 1 429 ? 31.585  7.570   57.397 1.00 28.60  ? 631 PRO D CG  1 
ATOM   12670 C CD  . PRO D 1 429 ? 32.653  6.687   56.832 1.00 28.66  ? 631 PRO D CD  1 
ATOM   12671 N N   . SER D 1 430 ? 33.670  10.078  55.704 1.00 29.68  ? 632 SER D N   1 
ATOM   12672 C CA  . SER D 1 430 ? 34.217  11.427  55.703 1.00 29.06  ? 632 SER D CA  1 
ATOM   12673 C C   . SER D 1 430 ? 34.110  12.042  54.308 1.00 28.36  ? 632 SER D C   1 
ATOM   12674 O O   . SER D 1 430 ? 34.506  11.404  53.323 1.00 28.42  ? 632 SER D O   1 
ATOM   12675 C CB  . SER D 1 430 ? 35.677  11.406  56.154 1.00 29.39  ? 632 SER D CB  1 
ATOM   12676 O OG  . SER D 1 430 ? 36.250  12.700  56.101 1.00 33.74  ? 632 SER D OG  1 
ATOM   12677 N N   . PRO D 1 431 ? 33.581  13.257  54.182 1.00 30.00  ? 633 PRO D N   1 
ATOM   12678 C CA  . PRO D 1 431 ? 33.289  13.803  52.853 1.00 29.71  ? 633 PRO D CA  1 
ATOM   12679 C C   . PRO D 1 431 ? 34.550  14.199  52.108 1.00 29.77  ? 633 PRO D C   1 
ATOM   12680 O O   . PRO D 1 431 ? 35.560  14.583  52.701 1.00 30.19  ? 633 PRO D O   1 
ATOM   12681 C CB  . PRO D 1 431 ? 32.423  15.026  53.159 1.00 28.58  ? 633 PRO D CB  1 
ATOM   12682 C CG  . PRO D 1 431 ? 32.878  15.455  54.507 1.00 29.75  ? 633 PRO D CG  1 
ATOM   12683 C CD  . PRO D 1 431 ? 33.212  14.194  55.255 1.00 28.82  ? 633 PRO D CD  1 
ATOM   12684 N N   . LEU D 1 432 ? 34.470  14.121  50.779 1.00 30.17  ? 634 LEU D N   1 
ATOM   12685 C CA  . LEU D 1 432 ? 35.653  14.322  49.955 1.00 30.17  ? 634 LEU D CA  1 
ATOM   12686 C C   . LEU D 1 432 ? 36.090  15.777  49.889 1.00 31.44  ? 634 LEU D C   1 
ATOM   12687 O O   . LEU D 1 432 ? 37.287  16.039  49.743 1.00 31.47  ? 634 LEU D O   1 
ATOM   12688 C CB  . LEU D 1 432 ? 35.412  13.782  48.548 1.00 30.50  ? 634 LEU D CB  1 
ATOM   12689 C CG  . LEU D 1 432 ? 35.217  12.269  48.498 1.00 28.57  ? 634 LEU D CG  1 
ATOM   12690 C CD1 . LEU D 1 432 ? 34.940  11.815  47.085 1.00 27.76  ? 634 LEU D CD1 1 
ATOM   12691 C CD2 . LEU D 1 432 ? 36.424  11.562  49.074 1.00 25.80  ? 634 LEU D CD2 1 
ATOM   12692 N N   . MET D 1 433 ? 35.168  16.729  49.989 1.00 32.54  ? 635 MET D N   1 
ATOM   12693 C CA  . MET D 1 433 ? 35.594  18.119  50.065 1.00 33.33  ? 635 MET D CA  1 
ATOM   12694 C C   . MET D 1 433 ? 36.221  18.462  51.409 1.00 33.49  ? 635 MET D C   1 
ATOM   12695 O O   . MET D 1 433 ? 36.750  19.567  51.564 1.00 33.00  ? 635 MET D O   1 
ATOM   12696 C CB  . MET D 1 433 ? 34.425  19.066  49.777 1.00 27.21  ? 635 MET D CB  1 
ATOM   12697 C CG  . MET D 1 433 ? 33.921  19.007  48.343 1.00 29.61  ? 635 MET D CG  1 
ATOM   12698 S SD  . MET D 1 433 ? 32.785  20.345  47.916 1.00 35.33  ? 635 MET D SD  1 
ATOM   12699 C CE  . MET D 1 433 ? 31.286  19.862  48.753 1.00 34.41  ? 635 MET D CE  1 
ATOM   12700 N N   . GLY D 1 434 ? 36.188  17.549  52.365 1.00 35.26  ? 636 GLY D N   1 
ATOM   12701 C CA  . GLY D 1 434 ? 36.774  17.755  53.670 1.00 34.31  ? 636 GLY D CA  1 
ATOM   12702 C C   . GLY D 1 434 ? 35.715  18.020  54.727 1.00 34.09  ? 636 GLY D C   1 
ATOM   12703 O O   . GLY D 1 434 ? 34.570  18.378  54.436 1.00 35.33  ? 636 GLY D O   1 
ATOM   12704 N N   . GLY D 1 435 ? 36.120  17.854  55.977 1.00 35.13  ? 637 GLY D N   1 
ATOM   12705 C CA  . GLY D 1 435 ? 35.235  18.081  57.095 1.00 33.34  ? 637 GLY D CA  1 
ATOM   12706 C C   . GLY D 1 435 ? 34.636  16.813  57.667 1.00 31.90  ? 637 GLY D C   1 
ATOM   12707 O O   . GLY D 1 435 ? 35.135  15.702  57.481 1.00 31.51  ? 637 GLY D O   1 
ATOM   12708 N N   . PHE D 1 436 ? 33.538  17.001  58.390 1.00 30.91  ? 638 PHE D N   1 
ATOM   12709 C CA  . PHE D 1 436 ? 32.936  15.964  59.217 1.00 30.69  ? 638 PHE D CA  1 
ATOM   12710 C C   . PHE D 1 436 ? 31.687  15.424  58.534 1.00 32.36  ? 638 PHE D C   1 
ATOM   12711 O O   . PHE D 1 436 ? 30.732  16.171  58.303 1.00 34.29  ? 638 PHE D O   1 
ATOM   12712 C CB  . PHE D 1 436 ? 32.581  16.525  60.592 1.00 37.22  ? 638 PHE D CB  1 
ATOM   12713 C CG  . PHE D 1 436 ? 33.754  17.070  61.345 1.00 36.66  ? 638 PHE D CG  1 
ATOM   12714 C CD1 . PHE D 1 436 ? 34.541  16.243  62.121 1.00 36.04  ? 638 PHE D CD1 1 
ATOM   12715 C CD2 . PHE D 1 436 ? 34.076  18.412  61.270 1.00 36.32  ? 638 PHE D CD2 1 
ATOM   12716 C CE1 . PHE D 1 436 ? 35.622  16.745  62.814 1.00 36.45  ? 638 PHE D CE1 1 
ATOM   12717 C CE2 . PHE D 1 436 ? 35.157  18.918  61.960 1.00 36.58  ? 638 PHE D CE2 1 
ATOM   12718 C CZ  . PHE D 1 436 ? 35.931  18.084  62.733 1.00 36.17  ? 638 PHE D CZ  1 
ATOM   12719 N N   . GLY D 1 437 ? 31.689  14.132  58.217 1.00 32.71  ? 639 GLY D N   1 
ATOM   12720 C CA  . GLY D 1 437 ? 30.493  13.478  57.721 1.00 33.10  ? 639 GLY D CA  1 
ATOM   12721 C C   . GLY D 1 437 ? 29.599  13.066  58.879 1.00 34.18  ? 639 GLY D C   1 
ATOM   12722 O O   . GLY D 1 437 ? 30.074  12.605  59.913 1.00 34.21  ? 639 GLY D O   1 
ATOM   12723 N N   . MET D 1 438 ? 28.294  13.230  58.685 1.00 31.84  ? 640 MET D N   1 
ATOM   12724 C CA  . MET D 1 438 ? 27.328  12.964  59.739 1.00 32.45  ? 640 MET D CA  1 
ATOM   12725 C C   . MET D 1 438 ? 26.056  12.390  59.139 1.00 33.16  ? 640 MET D C   1 
ATOM   12726 O O   . MET D 1 438 ? 25.555  12.895  58.132 1.00 33.19  ? 640 MET D O   1 
ATOM   12727 C CB  . MET D 1 438 ? 27.004  14.238  60.526 1.00 34.54  ? 640 MET D CB  1 
ATOM   12728 C CG  . MET D 1 438 ? 28.167  14.789  61.333 1.00 39.05  ? 640 MET D CG  1 
ATOM   12729 S SD  . MET D 1 438 ? 27.792  16.360  62.124 1.00 43.52  ? 640 MET D SD  1 
ATOM   12730 C CE  . MET D 1 438 ? 26.638  15.826  63.378 1.00 43.41  ? 640 MET D CE  1 
ATOM   12731 N N   . LYS D 1 439 ? 25.537  11.332  59.762 1.00 32.27  ? 641 LYS D N   1 
ATOM   12732 C CA  . LYS D 1 439 ? 24.240  10.805  59.367 1.00 34.21  ? 641 LYS D CA  1 
ATOM   12733 C C   . LYS D 1 439 ? 23.107  11.738  59.752 1.00 34.16  ? 641 LYS D C   1 
ATOM   12734 O O   . LYS D 1 439 ? 22.110  11.820  59.027 1.00 34.88  ? 641 LYS D O   1 
ATOM   12735 C CB  . LYS D 1 439 ? 24.010  9.432   60.000 1.00 29.54  ? 641 LYS D CB  1 
ATOM   12736 C CG  . LYS D 1 439 ? 24.886  8.337   59.435 1.00 35.44  ? 641 LYS D CG  1 
ATOM   12737 C CD  . LYS D 1 439 ? 24.465  6.977   59.956 1.00 41.86  ? 641 LYS D CD  1 
ATOM   12738 C CE  . LYS D 1 439 ? 24.694  6.867   61.453 1.00 44.23  ? 641 LYS D CE  1 
ATOM   12739 N NZ  . LYS D 1 439 ? 24.381  5.505   61.963 1.00 44.98  ? 641 LYS D NZ  1 
ATOM   12740 N N   . HIS D 1 440 ? 23.241  12.441  60.871 1.00 35.94  ? 642 HIS D N   1 
ATOM   12741 C CA  . HIS D 1 440 ? 22.283  13.454  61.299 1.00 35.78  ? 642 HIS D CA  1 
ATOM   12742 C C   . HIS D 1 440 ? 23.066  14.739  61.519 1.00 34.13  ? 642 HIS D C   1 
ATOM   12743 O O   . HIS D 1 440 ? 23.448  15.060  62.652 1.00 34.24  ? 642 HIS D O   1 
ATOM   12744 C CB  . HIS D 1 440 ? 21.548  13.024  62.568 1.00 32.79  ? 642 HIS D CB  1 
ATOM   12745 C CG  . HIS D 1 440 ? 20.855  11.704  62.444 1.00 37.90  ? 642 HIS D CG  1 
ATOM   12746 N ND1 . HIS D 1 440 ? 19.744  11.515  61.651 1.00 39.16  ? 642 HIS D ND1 1 
ATOM   12747 C CD2 . HIS D 1 440 ? 21.116  10.505  63.017 1.00 38.99  ? 642 HIS D CD2 1 
ATOM   12748 C CE1 . HIS D 1 440 ? 19.352  10.257  61.740 1.00 40.35  ? 642 HIS D CE1 1 
ATOM   12749 N NE2 . HIS D 1 440 ? 20.168  9.623   62.562 1.00 41.57  ? 642 HIS D NE2 1 
ATOM   12750 N N   . PRO D 1 441 ? 23.340  15.491  60.458 1.00 34.53  ? 643 PRO D N   1 
ATOM   12751 C CA  . PRO D 1 441 ? 24.064  16.750  60.613 1.00 32.94  ? 643 PRO D CA  1 
ATOM   12752 C C   . PRO D 1 441 ? 23.170  17.795  61.252 1.00 32.20  ? 643 PRO D C   1 
ATOM   12753 O O   . PRO D 1 441 ? 21.981  17.536  61.494 1.00 32.28  ? 643 PRO D O   1 
ATOM   12754 C CB  . PRO D 1 441 ? 24.416  17.125  59.168 1.00 31.18  ? 643 PRO D CB  1 
ATOM   12755 C CG  . PRO D 1 441 ? 23.334  16.522  58.369 1.00 31.00  ? 643 PRO D CG  1 
ATOM   12756 C CD  . PRO D 1 441 ? 22.998  15.227  59.052 1.00 30.96  ? 643 PRO D CD  1 
ATOM   12757 N N   . PRO D 1 442 ? 23.694  18.979  61.552 1.00 35.03  ? 644 PRO D N   1 
ATOM   12758 C CA  . PRO D 1 442 ? 22.836  20.067  62.015 1.00 34.52  ? 644 PRO D CA  1 
ATOM   12759 C C   . PRO D 1 442 ? 21.703  20.312  61.037 1.00 34.81  ? 644 PRO D C   1 
ATOM   12760 O O   . PRO D 1 442 ? 21.922  20.377  59.819 1.00 34.54  ? 644 PRO D O   1 
ATOM   12761 C CB  . PRO D 1 442 ? 23.793  21.263  62.086 1.00 35.09  ? 644 PRO D CB  1 
ATOM   12762 C CG  . PRO D 1 442 ? 25.099  20.639  62.404 1.00 35.44  ? 644 PRO D CG  1 
ATOM   12763 C CD  . PRO D 1 442 ? 25.123  19.303  61.715 1.00 35.17  ? 644 PRO D CD  1 
ATOM   12764 N N   . PRO D 1 443 ? 20.477  20.445  61.533 1.00 31.03  ? 645 PRO D N   1 
ATOM   12765 C CA  . PRO D 1 443 ? 19.313  20.432  60.645 1.00 31.08  ? 645 PRO D CA  1 
ATOM   12766 C C   . PRO D 1 443 ? 19.239  21.679  59.783 1.00 31.57  ? 645 PRO D C   1 
ATOM   12767 O O   . PRO D 1 443 ? 19.837  22.715  60.078 1.00 31.50  ? 645 PRO D O   1 
ATOM   12768 C CB  . PRO D 1 443 ? 18.134  20.370  61.619 1.00 31.62  ? 645 PRO D CB  1 
ATOM   12769 C CG  . PRO D 1 443 ? 18.643  21.042  62.842 1.00 31.50  ? 645 PRO D CG  1 
ATOM   12770 C CD  . PRO D 1 443 ? 20.096  20.677  62.937 1.00 31.96  ? 645 PRO D CD  1 
ATOM   12771 N N   . GLN D 1 444 ? 18.484  21.564  58.696 1.00 29.81  ? 646 GLN D N   1 
ATOM   12772 C CA  . GLN D 1 444 ? 18.189  22.733  57.884 1.00 30.87  ? 646 GLN D CA  1 
ATOM   12773 C C   . GLN D 1 444 ? 17.167  23.618  58.578 1.00 30.64  ? 646 GLN D C   1 
ATOM   12774 O O   . GLN D 1 444 ? 16.198  23.133  59.166 1.00 30.76  ? 646 GLN D O   1 
ATOM   12775 C CB  . GLN D 1 444 ? 17.665  22.327  56.513 1.00 22.29  ? 646 GLN D CB  1 
ATOM   12776 C CG  . GLN D 1 444 ? 18.700  21.725  55.614 1.00 27.09  ? 646 GLN D CG  1 
ATOM   12777 C CD  . GLN D 1 444 ? 18.131  21.366  54.273 1.00 28.42  ? 646 GLN D CD  1 
ATOM   12778 O OE1 . GLN D 1 444 ? 16.943  21.080  54.144 1.00 29.47  ? 646 GLN D OE1 1 
ATOM   12779 N NE2 . GLN D 1 444 ? 18.965  21.420  53.253 1.00 28.53  ? 646 GLN D NE2 1 
ATOM   12780 N N   . ILE D 1 445 ? 17.384  24.924  58.500 1.00 31.95  ? 647 ILE D N   1 
ATOM   12781 C CA  . ILE D 1 445 ? 16.510  25.909  59.120 1.00 30.03  ? 647 ILE D CA  1 
ATOM   12782 C C   . ILE D 1 445 ? 15.851  26.686  57.992 1.00 30.09  ? 647 ILE D C   1 
ATOM   12783 O O   . ILE D 1 445 ? 16.507  27.491  57.322 1.00 31.22  ? 647 ILE D O   1 
ATOM   12784 C CB  . ILE D 1 445 ? 17.281  26.844  60.055 1.00 33.83  ? 647 ILE D CB  1 
ATOM   12785 C CG1 . ILE D 1 445 ? 17.948  26.045  61.164 1.00 32.78  ? 647 ILE D CG1 1 
ATOM   12786 C CG2 . ILE D 1 445 ? 16.347  27.856  60.677 1.00 31.56  ? 647 ILE D CG2 1 
ATOM   12787 C CD1 . ILE D 1 445 ? 18.951  26.845  61.921 1.00 32.34  ? 647 ILE D CD1 1 
ATOM   12788 N N   . LEU D 1 446 ? 14.558  26.465  57.792 1.00 29.57  ? 648 LEU D N   1 
ATOM   12789 C CA  . LEU D 1 446 ? 13.829  27.047  56.678 1.00 29.04  ? 648 LEU D CA  1 
ATOM   12790 C C   . LEU D 1 446 ? 13.014  28.237  57.165 1.00 28.98  ? 648 LEU D C   1 
ATOM   12791 O O   . LEU D 1 446 ? 12.507  28.242  58.289 1.00 30.91  ? 648 LEU D O   1 
ATOM   12792 C CB  . LEU D 1 446 ? 12.911  26.014  56.018 1.00 27.03  ? 648 LEU D CB  1 
ATOM   12793 C CG  . LEU D 1 446 ? 13.531  25.026  55.023 1.00 26.88  ? 648 LEU D CG  1 
ATOM   12794 C CD1 . LEU D 1 446 ? 14.216  25.759  53.887 1.00 27.34  ? 648 LEU D CD1 1 
ATOM   12795 C CD2 . LEU D 1 446 ? 14.498  24.076  55.708 1.00 26.77  ? 648 LEU D CD2 1 
ATOM   12796 N N   . ILE D 1 447 ? 12.893  29.249  56.309 1.00 30.78  ? 649 ILE D N   1 
ATOM   12797 C CA  . ILE D 1 447 ? 12.263  30.509  56.690 1.00 30.42  ? 649 ILE D CA  1 
ATOM   12798 C C   . ILE D 1 447 ? 11.620  31.128  55.455 1.00 30.99  ? 649 ILE D C   1 
ATOM   12799 O O   . ILE D 1 447 ? 12.100  30.941  54.334 1.00 31.68  ? 649 ILE D O   1 
ATOM   12800 C CB  . ILE D 1 447 ? 13.300  31.457  57.339 1.00 32.96  ? 649 ILE D CB  1 
ATOM   12801 C CG1 . ILE D 1 447 ? 12.635  32.704  57.918 1.00 32.55  ? 649 ILE D CG1 1 
ATOM   12802 C CG2 . ILE D 1 447 ? 14.380  31.847  56.343 1.00 32.28  ? 649 ILE D CG2 1 
ATOM   12803 C CD1 . ILE D 1 447 ? 13.568  33.531  58.771 1.00 32.72  ? 649 ILE D CD1 1 
ATOM   12804 N N   . LYS D 1 448 ? 10.513  31.843  55.656 1.00 31.77  ? 650 LYS D N   1 
ATOM   12805 C CA  . LYS D 1 448 ? 9.947   32.670  54.596 1.00 33.05  ? 650 LYS D CA  1 
ATOM   12806 C C   . LYS D 1 448 ? 9.096   33.765  55.219 1.00 34.33  ? 650 LYS D C   1 
ATOM   12807 O O   . LYS D 1 448 ? 8.735   33.705  56.397 1.00 34.00  ? 650 LYS D O   1 
ATOM   12808 C CB  . LYS D 1 448 ? 9.088   31.874  53.611 1.00 29.45  ? 650 LYS D CB  1 
ATOM   12809 C CG  . LYS D 1 448 ? 7.780   31.418  54.203 1.00 31.28  ? 650 LYS D CG  1 
ATOM   12810 C CD  . LYS D 1 448 ? 6.909   30.713  53.187 1.00 32.62  ? 650 LYS D CD  1 
ATOM   12811 C CE  . LYS D 1 448 ? 6.402   31.661  52.127 1.00 36.73  ? 650 LYS D CE  1 
ATOM   12812 N NZ  . LYS D 1 448 ? 5.533   30.952  51.152 1.00 35.84  ? 650 LYS D NZ  1 
ATOM   12813 N N   . ASN D 1 449 ? 8.776   34.765  54.400 1.00 37.87  ? 651 ASN D N   1 
ATOM   12814 C CA  . ASN D 1 449 ? 7.822   35.799  54.780 1.00 38.95  ? 651 ASN D CA  1 
ATOM   12815 C C   . ASN D 1 449 ? 6.402   35.301  54.548 1.00 39.81  ? 651 ASN D C   1 
ATOM   12816 O O   . ASN D 1 449 ? 6.072   34.841  53.452 1.00 40.71  ? 651 ASN D O   1 
ATOM   12817 C CB  . ASN D 1 449 ? 8.055   37.074  53.969 1.00 34.78  ? 651 ASN D CB  1 
ATOM   12818 C CG  . ASN D 1 449 ? 9.431   37.654  54.175 1.00 37.86  ? 651 ASN D CG  1 
ATOM   12819 O OD1 . ASN D 1 449 ? 10.111  38.022  53.221 1.00 39.24  ? 651 ASN D OD1 1 
ATOM   12820 N ND2 . ASN D 1 449 ? 9.858   37.723  55.423 1.00 39.92  ? 651 ASN D ND2 1 
ATOM   12821 N N   . THR D 1 450 ? 5.565   35.398  55.572 1.00 38.91  ? 652 THR D N   1 
ATOM   12822 C CA  . THR D 1 450 ? 4.162   35.034  55.416 1.00 40.26  ? 652 THR D CA  1 
ATOM   12823 C C   . THR D 1 450 ? 3.502   35.959  54.403 1.00 38.80  ? 652 THR D C   1 
ATOM   12824 O O   . THR D 1 450 ? 3.534   37.182  54.579 1.00 37.62  ? 652 THR D O   1 
ATOM   12825 C CB  . THR D 1 450 ? 3.425   35.128  56.744 1.00 39.32  ? 652 THR D CB  1 
ATOM   12826 O OG1 . THR D 1 450 ? 3.995   34.209  57.682 1.00 46.88  ? 652 THR D OG1 1 
ATOM   12827 C CG2 . THR D 1 450 ? 1.953   34.803  56.548 1.00 39.11  ? 652 THR D CG2 1 
ATOM   12828 N N   . PRO D 1 451 ? 2.903   35.428  53.339 1.00 39.78  ? 653 PRO D N   1 
ATOM   12829 C CA  . PRO D 1 451 ? 2.292   36.303  52.329 1.00 39.53  ? 653 PRO D CA  1 
ATOM   12830 C C   . PRO D 1 451 ? 1.082   37.037  52.885 1.00 39.87  ? 653 PRO D C   1 
ATOM   12831 O O   . PRO D 1 451 ? 0.200   36.443  53.508 1.00 40.13  ? 653 PRO D O   1 
ATOM   12832 C CB  . PRO D 1 451 ? 1.907   35.328  51.213 1.00 35.85  ? 653 PRO D CB  1 
ATOM   12833 C CG  . PRO D 1 451 ? 1.725   34.033  51.903 1.00 34.89  ? 653 PRO D CG  1 
ATOM   12834 C CD  . PRO D 1 451 ? 2.746   34.006  52.998 1.00 35.61  ? 653 PRO D CD  1 
ATOM   12835 N N   . VAL D 1 452 ? 1.047   38.343  52.655 1.00 43.40  ? 654 VAL D N   1 
ATOM   12836 C CA  . VAL D 1 452 ? -0.088  39.184  53.019 1.00 43.39  ? 654 VAL D CA  1 
ATOM   12837 C C   . VAL D 1 452 ? -0.715  39.694  51.727 1.00 43.50  ? 654 VAL D C   1 
ATOM   12838 O O   . VAL D 1 452 ? -0.114  40.547  51.058 1.00 43.90  ? 654 VAL D O   1 
ATOM   12839 C CB  . VAL D 1 452 ? 0.336   40.348  53.924 1.00 47.09  ? 654 VAL D CB  1 
ATOM   12840 C CG1 . VAL D 1 452 ? -0.858  41.222  54.234 1.00 46.64  ? 654 VAL D CG1 1 
ATOM   12841 C CG2 . VAL D 1 452 ? 0.964   39.822  55.202 1.00 45.44  ? 654 VAL D CG2 1 
ATOM   12842 N N   . PRO D 1 453 ? -1.889  39.211  51.341 1.00 44.51  ? 655 PRO D N   1 
ATOM   12843 C CA  . PRO D 1 453 ? -2.434  39.563  50.029 1.00 45.08  ? 655 PRO D CA  1 
ATOM   12844 C C   . PRO D 1 453 ? -2.948  40.990  49.989 1.00 46.61  ? 655 PRO D C   1 
ATOM   12845 O O   . PRO D 1 453 ? -3.156  41.635  51.019 1.00 46.02  ? 655 PRO D O   1 
ATOM   12846 C CB  . PRO D 1 453 ? -3.575  38.558  49.843 1.00 42.82  ? 655 PRO D CB  1 
ATOM   12847 C CG  . PRO D 1 453 ? -4.011  38.251  51.235 1.00 43.10  ? 655 PRO D CG  1 
ATOM   12848 C CD  . PRO D 1 453 ? -2.767  38.288  52.078 1.00 42.69  ? 655 PRO D CD  1 
ATOM   12849 N N   . ALA D 1 454 ? -3.153  41.479  48.770 1.00 44.70  ? 656 ALA D N   1 
ATOM   12850 C CA  . ALA D 1 454 ? -3.725  42.794  48.539 1.00 46.81  ? 656 ALA D CA  1 
ATOM   12851 C C   . ALA D 1 454 ? -5.247  42.734  48.655 1.00 49.68  ? 656 ALA D C   1 
ATOM   12852 O O   . ALA D 1 454 ? -5.826  41.762  49.146 1.00 50.64  ? 656 ALA D O   1 
ATOM   12853 C CB  . ALA D 1 454 ? -3.296  43.334  47.176 1.00 48.90  ? 656 ALA D CB  1 
ATOM   12854 N N   . ASP D 1 455 ? -5.903  43.799  48.213 1.00 48.33  ? 657 ASP D N   1 
ATOM   12855 C CA  . ASP D 1 455 ? -7.345  43.902  48.367 1.00 49.66  ? 657 ASP D CA  1 
ATOM   12856 C C   . ASP D 1 455 ? -8.066  42.854  47.520 1.00 47.96  ? 657 ASP D C   1 
ATOM   12857 O O   . ASP D 1 455 ? -7.799  42.726  46.319 1.00 47.51  ? 657 ASP D O   1 
ATOM   12858 C CB  . ASP D 1 455 ? -7.815  45.307  47.992 1.00 49.63  ? 657 ASP D CB  1 
ATOM   12859 C CG  . ASP D 1 455 ? -7.346  45.733  46.617 1.00 53.88  ? 657 ASP D CG  1 
ATOM   12860 O OD1 . ASP D 1 455 ? -6.503  45.030  46.023 1.00 56.11  ? 657 ASP D OD1 1 
ATOM   12861 O OD2 . ASP D 1 455 ? -7.822  46.777  46.127 1.00 55.81  ? 657 ASP D OD2 1 
ATOM   12862 N N   . PRO D 1 456 ? -8.976  42.087  48.111 1.00 46.49  ? 658 PRO D N   1 
ATOM   12863 C CA  . PRO D 1 456 ? -9.744  41.104  47.346 1.00 46.17  ? 658 PRO D CA  1 
ATOM   12864 C C   . PRO D 1 456 ? -10.694 41.783  46.375 1.00 46.68  ? 658 PRO D C   1 
ATOM   12865 O O   . PRO D 1 456 ? -10.969 42.986  46.494 1.00 46.99  ? 658 PRO D O   1 
ATOM   12866 C CB  . PRO D 1 456 ? -10.509 40.340  48.436 1.00 44.88  ? 658 PRO D CB  1 
ATOM   12867 C CG  . PRO D 1 456 ? -9.687  40.517  49.658 1.00 44.87  ? 658 PRO D CG  1 
ATOM   12868 C CD  . PRO D 1 456 ? -9.155  41.910  49.561 1.00 45.47  ? 658 PRO D CD  1 
ATOM   12869 N N   . PRO D 1 457 ? -11.215 41.042  45.393 1.00 43.99  ? 659 PRO D N   1 
ATOM   12870 C CA  . PRO D 1 457 ? -12.075 41.669  44.375 1.00 44.71  ? 659 PRO D CA  1 
ATOM   12871 C C   . PRO D 1 457 ? -13.425 42.160  44.882 1.00 45.27  ? 659 PRO D C   1 
ATOM   12872 O O   . PRO D 1 457 ? -14.115 42.864  44.133 1.00 45.88  ? 659 PRO D O   1 
ATOM   12873 C CB  . PRO D 1 457 ? -12.233 40.556  43.330 1.00 43.26  ? 659 PRO D CB  1 
ATOM   12874 C CG  . PRO D 1 457 ? -11.988 39.302  44.077 1.00 42.58  ? 659 PRO D CG  1 
ATOM   12875 C CD  . PRO D 1 457 ? -10.935 39.632  45.077 1.00 42.41  ? 659 PRO D CD  1 
ATOM   12876 N N   . THR D 1 458 ? -13.843 41.783  46.092 1.00 41.23  ? 660 THR D N   1 
ATOM   12877 C CA  . THR D 1 458 ? -15.124 42.108  46.741 1.00 41.17  ? 660 THR D CA  1 
ATOM   12878 C C   . THR D 1 458 ? -16.244 41.227  46.184 1.00 39.86  ? 660 THR D C   1 
ATOM   12879 O O   . THR D 1 458 ? -17.299 41.101  46.823 1.00 39.90  ? 660 THR D O   1 
ATOM   12880 C CB  . THR D 1 458 ? -15.506 43.598  46.617 1.00 40.15  ? 660 THR D CB  1 
ATOM   12881 O OG1 . THR D 1 458 ? -14.463 44.408  47.171 1.00 41.44  ? 660 THR D OG1 1 
ATOM   12882 C CG2 . THR D 1 458 ? -16.794 43.924  47.357 1.00 38.77  ? 660 THR D CG2 1 
ATOM   12883 N N   . ALA D 1 459 ? -16.036 40.567  45.049 1.00 39.16  ? 661 ALA D N   1 
ATOM   12884 C CA  . ALA D 1 459 ? -16.921 39.511  44.579 1.00 38.07  ? 661 ALA D CA  1 
ATOM   12885 C C   . ALA D 1 459 ? -16.133 38.212  44.597 1.00 38.14  ? 661 ALA D C   1 
ATOM   12886 O O   . ALA D 1 459 ? -15.009 38.163  44.089 1.00 39.15  ? 661 ALA D O   1 
ATOM   12887 C CB  . ALA D 1 459 ? -17.455 39.803  43.174 1.00 36.61  ? 661 ALA D CB  1 
ATOM   12888 N N   . PHE D 1 460 ? -16.717 37.168  45.185 1.00 37.52  ? 662 PHE D N   1 
ATOM   12889 C CA  . PHE D 1 460 ? -15.968 35.942  45.426 1.00 37.22  ? 662 PHE D CA  1 
ATOM   12890 C C   . PHE D 1 460 ? -15.414 35.355  44.137 1.00 37.52  ? 662 PHE D C   1 
ATOM   12891 O O   . PHE D 1 460 ? -16.101 35.280  43.116 1.00 37.55  ? 662 PHE D O   1 
ATOM   12892 C CB  . PHE D 1 460 ? -16.830 34.895  46.124 1.00 34.13  ? 662 PHE D CB  1 
ATOM   12893 C CG  . PHE D 1 460 ? -16.159 33.559  46.229 1.00 34.22  ? 662 PHE D CG  1 
ATOM   12894 C CD1 . PHE D 1 460 ? -15.183 33.337  47.178 1.00 33.76  ? 662 PHE D CD1 1 
ATOM   12895 C CD2 . PHE D 1 460 ? -16.485 32.534  45.359 1.00 33.47  ? 662 PHE D CD2 1 
ATOM   12896 C CE1 . PHE D 1 460 ? -14.557 32.122  47.265 1.00 33.27  ? 662 PHE D CE1 1 
ATOM   12897 C CE2 . PHE D 1 460 ? -15.857 31.317  45.444 1.00 33.57  ? 662 PHE D CE2 1 
ATOM   12898 C CZ  . PHE D 1 460 ? -14.891 31.114  46.395 1.00 33.75  ? 662 PHE D CZ  1 
ATOM   12899 N N   . ASN D 1 461 ? -14.157 34.926  44.200 1.00 39.10  ? 663 ASN D N   1 
ATOM   12900 C CA  . ASN D 1 461 ? -13.488 34.277  43.082 1.00 40.37  ? 663 ASN D CA  1 
ATOM   12901 C C   . ASN D 1 461 ? -12.753 33.064  43.626 1.00 40.53  ? 663 ASN D C   1 
ATOM   12902 O O   . ASN D 1 461 ? -12.049 33.168  44.634 1.00 40.17  ? 663 ASN D O   1 
ATOM   12903 C CB  . ASN D 1 461 ? -12.521 35.236  42.384 1.00 42.02  ? 663 ASN D CB  1 
ATOM   12904 C CG  . ASN D 1 461 ? -12.029 34.701  41.060 1.00 44.18  ? 663 ASN D CG  1 
ATOM   12905 O OD1 . ASN D 1 461 ? -12.727 33.944  40.386 1.00 45.77  ? 663 ASN D OD1 1 
ATOM   12906 N ND2 . ASN D 1 461 ? -10.825 35.100  40.672 1.00 46.23  ? 663 ASN D ND2 1 
ATOM   12907 N N   . LYS D 1 462 ? -12.916 31.917  42.967 1.00 41.31  ? 664 LYS D N   1 
ATOM   12908 C CA  . LYS D 1 462 ? -12.351 30.685  43.504 1.00 42.32  ? 664 LYS D CA  1 
ATOM   12909 C C   . LYS D 1 462 ? -10.852 30.609  43.264 1.00 42.03  ? 664 LYS D C   1 
ATOM   12910 O O   . LYS D 1 462 ? -10.162 29.784  43.873 1.00 40.62  ? 664 LYS D O   1 
ATOM   12911 C CB  . LYS D 1 462 ? -13.047 29.472  42.892 1.00 38.37  ? 664 LYS D CB  1 
ATOM   12912 C CG  . LYS D 1 462 ? -12.830 29.285  41.406 1.00 43.19  ? 664 LYS D CG  1 
ATOM   12913 C CD  . LYS D 1 462 ? -13.704 28.161  40.883 1.00 48.86  ? 664 LYS D CD  1 
ATOM   12914 C CE  . LYS D 1 462 ? -13.429 27.867  39.423 1.00 50.38  ? 664 LYS D CE  1 
ATOM   12915 N NZ  . LYS D 1 462 ? -12.111 27.207  39.242 1.00 51.17  ? 664 LYS D NZ  1 
ATOM   12916 N N   . ASP D 1 463 ? -10.330 31.452  42.378 1.00 44.01  ? 665 ASP D N   1 
ATOM   12917 C CA  . ASP D 1 463 ? -8.907  31.414  42.074 1.00 45.35  ? 665 ASP D CA  1 
ATOM   12918 C C   . ASP D 1 463 ? -8.088  31.814  43.292 1.00 43.49  ? 665 ASP D C   1 
ATOM   12919 O O   . ASP D 1 463 ? -8.528  32.610  44.124 1.00 44.20  ? 665 ASP D O   1 
ATOM   12920 C CB  . ASP D 1 463 ? -8.590  32.339  40.901 1.00 43.73  ? 665 ASP D CB  1 
ATOM   12921 C CG  . ASP D 1 463 ? -9.128  31.817  39.587 1.00 49.78  ? 665 ASP D CG  1 
ATOM   12922 O OD1 . ASP D 1 463 ? -9.483  30.621  39.525 1.00 52.50  ? 665 ASP D OD1 1 
ATOM   12923 O OD2 . ASP D 1 463 ? -9.190  32.597  38.615 1.00 53.26  ? 665 ASP D OD2 1 
ATOM   12924 N N   . LYS D 1 464 ? -6.889  31.249  43.399 1.00 39.82  ? 666 LYS D N   1 
ATOM   12925 C CA  . LYS D 1 464 ? -5.985  31.657  44.462 1.00 38.32  ? 666 LYS D CA  1 
ATOM   12926 C C   . LYS D 1 464 ? -5.520  33.086  44.215 1.00 38.84  ? 666 LYS D C   1 
ATOM   12927 O O   . LYS D 1 464 ? -5.363  33.518  43.070 1.00 39.12  ? 666 LYS D O   1 
ATOM   12928 C CB  . LYS D 1 464 ? -4.790  30.706  44.552 1.00 35.94  ? 666 LYS D CB  1 
ATOM   12929 C CG  . LYS D 1 464 ? -3.904  30.669  43.326 1.00 33.70  ? 666 LYS D CG  1 
ATOM   12930 C CD  . LYS D 1 464 ? -2.777  29.675  43.523 1.00 33.30  ? 666 LYS D CD  1 
ATOM   12931 C CE  . LYS D 1 464 ? -1.883  29.579  42.302 1.00 32.88  ? 666 LYS D CE  1 
ATOM   12932 N NZ  . LYS D 1 464 ? -0.797  28.580  42.503 1.00 31.67  ? 666 LYS D NZ  1 
ATOM   12933 N N   . LEU D 1 465 ? -5.316  33.827  45.300 1.00 39.58  ? 667 LEU D N   1 
ATOM   12934 C CA  . LEU D 1 465 ? -4.991  35.239  45.180 1.00 39.77  ? 667 LEU D CA  1 
ATOM   12935 C C   . LEU D 1 465 ? -3.595  35.410  44.601 1.00 40.32  ? 667 LEU D C   1 
ATOM   12936 O O   . LEU D 1 465 ? -2.619  34.875  45.131 1.00 40.41  ? 667 LEU D O   1 
ATOM   12937 C CB  . LEU D 1 465 ? -5.094  35.912  46.546 1.00 37.11  ? 667 LEU D CB  1 
ATOM   12938 C CG  . LEU D 1 465 ? -6.492  35.859  47.165 1.00 36.46  ? 667 LEU D CG  1 
ATOM   12939 C CD1 . LEU D 1 465 ? -6.490  36.432  48.567 1.00 37.25  ? 667 LEU D CD1 1 
ATOM   12940 C CD2 . LEU D 1 465 ? -7.501  36.575  46.288 1.00 36.04  ? 667 LEU D CD2 1 
ATOM   12941 N N   . ASN D 1 466 ? -3.508  36.133  43.486 1.00 38.36  ? 668 ASN D N   1 
ATOM   12942 C CA  . ASN D 1 466 ? -2.238  36.381  42.816 1.00 39.84  ? 668 ASN D CA  1 
ATOM   12943 C C   . ASN D 1 466 ? -1.644  37.752  43.123 1.00 38.95  ? 668 ASN D C   1 
ATOM   12944 O O   . ASN D 1 466 ? -0.595  38.093  42.566 1.00 39.60  ? 668 ASN D O   1 
ATOM   12945 C CB  . ASN D 1 466 ? -2.403  36.199  41.306 1.00 35.33  ? 668 ASN D CB  1 
ATOM   12946 C CG  . ASN D 1 466 ? -3.455  37.108  40.728 1.00 40.69  ? 668 ASN D CG  1 
ATOM   12947 O OD1 . ASN D 1 466 ? -4.262  37.683  41.457 1.00 44.23  ? 668 ASN D OD1 1 
ATOM   12948 N ND2 . ASN D 1 466 ? -3.459  37.244  39.409 1.00 44.03  ? 668 ASN D ND2 1 
ATOM   12949 N N   . SER D 1 467 ? -2.278  38.550  43.977 1.00 42.99  ? 669 SER D N   1 
ATOM   12950 C CA  . SER D 1 467 ? -1.845  39.918  44.239 1.00 41.18  ? 669 SER D CA  1 
ATOM   12951 C C   . SER D 1 467 ? -1.361  40.040  45.679 1.00 39.95  ? 669 SER D C   1 
ATOM   12952 O O   . SER D 1 467 ? -2.105  39.731  46.614 1.00 38.81  ? 669 SER D O   1 
ATOM   12953 C CB  . SER D 1 467 ? -2.983  40.901  43.973 1.00 44.67  ? 669 SER D CB  1 
ATOM   12954 O OG  . SER D 1 467 ? -2.575  42.230  44.233 1.00 46.87  ? 669 SER D OG  1 
ATOM   12955 N N   . PHE D 1 468 ? -0.126  40.508  45.855 1.00 45.01  ? 670 PHE D N   1 
ATOM   12956 C CA  . PHE D 1 468 ? 0.495   40.539  47.171 1.00 43.91  ? 670 PHE D CA  1 
ATOM   12957 C C   . PHE D 1 468 ? 1.266   41.836  47.365 1.00 43.63  ? 670 PHE D C   1 
ATOM   12958 O O   . PHE D 1 468 ? 1.842   42.396  46.430 1.00 44.83  ? 670 PHE D O   1 
ATOM   12959 C CB  . PHE D 1 468 ? 1.426   39.341  47.380 1.00 38.34  ? 670 PHE D CB  1 
ATOM   12960 C CG  . PHE D 1 468 ? 0.724   38.022  47.319 1.00 39.36  ? 670 PHE D CG  1 
ATOM   12961 C CD1 . PHE D 1 468 ? 0.031   37.545  48.415 1.00 40.30  ? 670 PHE D CD1 1 
ATOM   12962 C CD2 . PHE D 1 468 ? 0.749   37.263  46.167 1.00 38.96  ? 670 PHE D CD2 1 
ATOM   12963 C CE1 . PHE D 1 468 ? -0.624  36.334  48.362 1.00 41.66  ? 670 PHE D CE1 1 
ATOM   12964 C CE2 . PHE D 1 468 ? 0.098   36.053  46.110 1.00 40.10  ? 670 PHE D CE2 1 
ATOM   12965 C CZ  . PHE D 1 468 ? -0.587  35.588  47.211 1.00 40.84  ? 670 PHE D CZ  1 
ATOM   12966 N N   . ILE D 1 469 ? 1.272   42.297  48.611 1.00 46.55  ? 671 ILE D N   1 
ATOM   12967 C CA  . ILE D 1 469 ? 1.978   43.510  49.000 1.00 46.07  ? 671 ILE D CA  1 
ATOM   12968 C C   . ILE D 1 469 ? 3.475   43.240  49.001 1.00 46.12  ? 671 ILE D C   1 
ATOM   12969 O O   . ILE D 1 469 ? 3.946   42.290  49.638 1.00 46.30  ? 671 ILE D O   1 
ATOM   12970 C CB  . ILE D 1 469 ? 1.499   43.976  50.386 1.00 45.10  ? 671 ILE D CB  1 
ATOM   12971 C CG1 . ILE D 1 469 ? 0.018   44.351  50.336 1.00 44.82  ? 671 ILE D CG1 1 
ATOM   12972 C CG2 . ILE D 1 469 ? 2.343   45.138  50.881 1.00 44.52  ? 671 ILE D CG2 1 
ATOM   12973 C CD1 . ILE D 1 469 ? -0.597  44.572  51.693 1.00 48.48  ? 671 ILE D CD1 1 
ATOM   12974 N N   . THR D 1 470 ? 4.233   44.073  48.290 1.00 49.30  ? 672 THR D N   1 
ATOM   12975 C CA  . THR D 1 470 ? 5.678   43.899  48.253 1.00 50.36  ? 672 THR D CA  1 
ATOM   12976 C C   . THR D 1 470 ? 6.246   44.078  49.654 1.00 49.27  ? 672 THR D C   1 
ATOM   12977 O O   . THR D 1 470 ? 6.041   45.115  50.290 1.00 48.05  ? 672 THR D O   1 
ATOM   12978 C CB  . THR D 1 470 ? 6.315   44.893  47.287 1.00 49.80  ? 672 THR D CB  1 
ATOM   12979 O OG1 . THR D 1 470 ? 5.794   44.675  45.971 1.00 54.46  ? 672 THR D OG1 1 
ATOM   12980 C CG2 . THR D 1 470 ? 7.817   44.707  47.261 1.00 50.17  ? 672 THR D CG2 1 
ATOM   12981 N N   . GLN D 1 471 ? 6.957   43.063  50.138 1.00 43.90  ? 673 GLN D N   1 
ATOM   12982 C CA  . GLN D 1 471 ? 7.287   43.003  51.551 1.00 43.16  ? 673 GLN D CA  1 
ATOM   12983 C C   . GLN D 1 471 ? 8.524   42.141  51.748 1.00 42.33  ? 673 GLN D C   1 
ATOM   12984 O O   . GLN D 1 471 ? 8.797   41.235  50.957 1.00 44.18  ? 673 GLN D O   1 
ATOM   12985 C CB  . GLN D 1 471 ? 6.084   42.458  52.325 1.00 44.07  ? 673 GLN D CB  1 
ATOM   12986 C CG  . GLN D 1 471 ? 6.138   42.558  53.823 1.00 48.39  ? 673 GLN D CG  1 
ATOM   12987 C CD  . GLN D 1 471 ? 4.797   42.217  54.436 1.00 51.71  ? 673 GLN D CD  1 
ATOM   12988 O OE1 . GLN D 1 471 ? 3.828   41.963  53.722 1.00 54.23  ? 673 GLN D OE1 1 
ATOM   12989 N NE2 . GLN D 1 471 ? 4.725   42.229  55.756 1.00 51.21  ? 673 GLN D NE2 1 
ATOM   12990 N N   . TYR D 1 472 ? 9.269   42.428  52.814 1.00 44.91  ? 674 TYR D N   1 
ATOM   12991 C CA  . TYR D 1 472 ? 10.438  41.636  53.166 1.00 43.61  ? 674 TYR D CA  1 
ATOM   12992 C C   . TYR D 1 472 ? 10.718  41.812  54.650 1.00 42.59  ? 674 TYR D C   1 
ATOM   12993 O O   . TYR D 1 472 ? 10.166  42.702  55.302 1.00 42.37  ? 674 TYR D O   1 
ATOM   12994 C CB  . TYR D 1 472 ? 11.667  42.014  52.330 1.00 40.95  ? 674 TYR D CB  1 
ATOM   12995 C CG  . TYR D 1 472 ? 12.226  43.393  52.581 1.00 41.15  ? 674 TYR D CG  1 
ATOM   12996 C CD1 . TYR D 1 472 ? 13.195  43.602  53.552 1.00 41.42  ? 674 TYR D CD1 1 
ATOM   12997 C CD2 . TYR D 1 472 ? 11.808  44.479  51.833 1.00 41.76  ? 674 TYR D CD2 1 
ATOM   12998 C CE1 . TYR D 1 472 ? 13.718  44.853  53.781 1.00 42.34  ? 674 TYR D CE1 1 
ATOM   12999 C CE2 . TYR D 1 472 ? 12.326  45.737  52.055 1.00 42.37  ? 674 TYR D CE2 1 
ATOM   13000 C CZ  . TYR D 1 472 ? 13.281  45.919  53.030 1.00 43.19  ? 674 TYR D CZ  1 
ATOM   13001 O OH  . TYR D 1 472 ? 13.800  47.173  53.252 1.00 43.36  ? 674 TYR D OH  1 
ATOM   13002 N N   . SER D 1 473 ? 11.571  40.944  55.186 1.00 41.18  ? 675 SER D N   1 
ATOM   13003 C CA  . SER D 1 473 ? 11.885  40.958  56.605 1.00 41.10  ? 675 SER D CA  1 
ATOM   13004 C C   . SER D 1 473 ? 13.389  41.043  56.818 1.00 40.86  ? 675 SER D C   1 
ATOM   13005 O O   . SER D 1 473 ? 14.188  40.758  55.924 1.00 41.08  ? 675 SER D O   1 
ATOM   13006 C CB  . SER D 1 473 ? 11.326  39.721  57.313 1.00 41.98  ? 675 SER D CB  1 
ATOM   13007 O OG  . SER D 1 473 ? 11.912  38.539  56.802 1.00 45.42  ? 675 SER D OG  1 
ATOM   13008 N N   . THR D 1 474 ? 13.764  41.451  58.029 1.00 44.47  ? 676 THR D N   1 
ATOM   13009 C CA  . THR D 1 474 ? 15.159  41.478  58.442 1.00 44.85  ? 676 THR D CA  1 
ATOM   13010 C C   . THR D 1 474 ? 15.235  41.242  59.944 1.00 43.43  ? 676 THR D C   1 
ATOM   13011 O O   . THR D 1 474 ? 14.245  41.383  60.666 1.00 44.49  ? 676 THR D O   1 
ATOM   13012 C CB  . THR D 1 474 ? 15.843  42.796  58.067 1.00 41.30  ? 676 THR D CB  1 
ATOM   13013 O OG1 . THR D 1 474 ? 17.242  42.704  58.355 1.00 44.62  ? 676 THR D OG1 1 
ATOM   13014 C CG2 . THR D 1 474 ? 15.250  43.948  58.848 1.00 40.86  ? 676 THR D CG2 1 
ATOM   13015 N N   . GLY D 1 475 ? 16.423  40.875  60.404 1.00 44.56  ? 677 GLY D N   1 
ATOM   13016 C CA  . GLY D 1 475 ? 16.602  40.573  61.809 1.00 42.89  ? 677 GLY D CA  1 
ATOM   13017 C C   . GLY D 1 475 ? 18.020  40.141  62.096 1.00 42.91  ? 677 GLY D C   1 
ATOM   13018 O O   . GLY D 1 475 ? 18.937  40.416  61.320 1.00 42.89  ? 677 GLY D O   1 
ATOM   13019 N N   . GLN D 1 476 ? 18.192  39.458  63.223 1.00 42.77  ? 678 GLN D N   1 
ATOM   13020 C CA  . GLN D 1 476 ? 19.496  38.998  63.671 1.00 43.32  ? 678 GLN D CA  1 
ATOM   13021 C C   . GLN D 1 476 ? 19.512  37.479  63.760 1.00 44.15  ? 678 GLN D C   1 
ATOM   13022 O O   . GLN D 1 476 ? 18.474  36.841  63.950 1.00 43.59  ? 678 GLN D O   1 
ATOM   13023 C CB  . GLN D 1 476 ? 19.855  39.594  65.040 1.00 41.84  ? 678 GLN D CB  1 
ATOM   13024 C CG  . GLN D 1 476 ? 19.939  41.114  65.073 1.00 43.91  ? 678 GLN D CG  1 
ATOM   13025 C CD  . GLN D 1 476 ? 20.997  41.666  64.149 1.00 45.72  ? 678 GLN D CD  1 
ATOM   13026 O OE1 . GLN D 1 476 ? 22.095  41.125  64.052 1.00 47.10  ? 678 GLN D OE1 1 
ATOM   13027 N NE2 . GLN D 1 476 ? 20.668  42.745  63.454 1.00 45.40  ? 678 GLN D NE2 1 
ATOM   13028 N N   . VAL D 1 477 ? 20.704  36.906  63.619 1.00 40.35  ? 679 VAL D N   1 
ATOM   13029 C CA  . VAL D 1 477 ? 20.937  35.476  63.772 1.00 40.70  ? 679 VAL D CA  1 
ATOM   13030 C C   . VAL D 1 477 ? 22.164  35.284  64.644 1.00 41.83  ? 679 VAL D C   1 
ATOM   13031 O O   . VAL D 1 477 ? 23.199  35.914  64.412 1.00 41.87  ? 679 VAL D O   1 
ATOM   13032 C CB  . VAL D 1 477 ? 21.136  34.768  62.417 1.00 39.48  ? 679 VAL D CB  1 
ATOM   13033 C CG1 . VAL D 1 477 ? 21.621  33.351  62.629 1.00 40.89  ? 679 VAL D CG1 1 
ATOM   13034 C CG2 . VAL D 1 477 ? 19.848  34.732  61.662 1.00 41.04  ? 679 VAL D CG2 1 
ATOM   13035 N N   . SER D 1 478 ? 22.051  34.417  65.641 1.00 39.86  ? 680 SER D N   1 
ATOM   13036 C CA  . SER D 1 478 ? 23.182  34.058  66.478 1.00 41.23  ? 680 SER D CA  1 
ATOM   13037 C C   . SER D 1 478 ? 23.319  32.545  66.528 1.00 41.06  ? 680 SER D C   1 
ATOM   13038 O O   . SER D 1 478 ? 22.362  31.834  66.847 1.00 41.79  ? 680 SER D O   1 
ATOM   13039 C CB  . SER D 1 478 ? 23.040  34.634  67.890 1.00 44.28  ? 680 SER D CB  1 
ATOM   13040 O OG  . SER D 1 478 ? 21.905  34.114  68.549 1.00 50.05  ? 680 SER D OG  1 
ATOM   13041 N N   . VAL D 1 479 ? 24.508  32.060  66.188 1.00 41.27  ? 681 VAL D N   1 
ATOM   13042 C CA  . VAL D 1 479 ? 24.817  30.638  66.195 1.00 41.17  ? 681 VAL D CA  1 
ATOM   13043 C C   . VAL D 1 479 ? 25.990  30.392  67.131 1.00 41.71  ? 681 VAL D C   1 
ATOM   13044 O O   . VAL D 1 479 ? 27.028  31.057  67.041 1.00 41.34  ? 681 VAL D O   1 
ATOM   13045 C CB  . VAL D 1 479 ? 25.114  30.109  64.774 1.00 39.09  ? 681 VAL D CB  1 
ATOM   13046 C CG1 . VAL D 1 479 ? 26.232  30.897  64.115 1.00 37.63  ? 681 VAL D CG1 1 
ATOM   13047 C CG2 . VAL D 1 479 ? 25.482  28.645  64.831 1.00 41.39  ? 681 VAL D CG2 1 
ATOM   13048 N N   . GLU D 1 480 ? 25.812  29.446  68.046 1.00 43.95  ? 682 GLU D N   1 
ATOM   13049 C CA  . GLU D 1 480 ? 26.846  29.050  68.988 1.00 45.13  ? 682 GLU D CA  1 
ATOM   13050 C C   . GLU D 1 480 ? 27.199  27.595  68.733 1.00 44.08  ? 682 GLU D C   1 
ATOM   13051 O O   . GLU D 1 480 ? 26.306  26.751  68.613 1.00 45.19  ? 682 GLU D O   1 
ATOM   13052 C CB  . GLU D 1 480 ? 26.376  29.244  70.433 1.00 46.28  ? 682 GLU D CB  1 
ATOM   13053 C CG  . GLU D 1 480 ? 27.400  28.879  71.493 1.00 55.16  ? 682 GLU D CG  1 
ATOM   13054 C CD  . GLU D 1 480 ? 26.879  29.124  72.896 1.00 61.68  ? 682 GLU D CD  1 
ATOM   13055 O OE1 . GLU D 1 480 ? 25.716  29.558  73.030 1.00 65.23  ? 682 GLU D OE1 1 
ATOM   13056 O OE2 . GLU D 1 480 ? 27.625  28.879  73.866 1.00 65.95  ? 682 GLU D OE2 1 
ATOM   13057 N N   . ILE D 1 481 ? 28.492  27.307  68.635 1.00 48.04  ? 683 ILE D N   1 
ATOM   13058 C CA  . ILE D 1 481 ? 28.983  25.946  68.468 1.00 46.44  ? 683 ILE D CA  1 
ATOM   13059 C C   . ILE D 1 481 ? 30.059  25.698  69.509 1.00 47.93  ? 683 ILE D C   1 
ATOM   13060 O O   . ILE D 1 481 ? 30.984  26.504  69.658 1.00 48.44  ? 683 ILE D O   1 
ATOM   13061 C CB  . ILE D 1 481 ? 29.538  25.696  67.054 1.00 44.42  ? 683 ILE D CB  1 
ATOM   13062 C CG1 . ILE D 1 481 ? 28.425  25.798  66.017 1.00 43.79  ? 683 ILE D CG1 1 
ATOM   13063 C CG2 . ILE D 1 481 ? 30.188  24.327  66.974 1.00 41.83  ? 683 ILE D CG2 1 
ATOM   13064 C CD1 . ILE D 1 481 ? 28.918  25.730  64.604 1.00 43.28  ? 683 ILE D CD1 1 
ATOM   13065 N N   . GLU D 1 482 ? 29.937  24.588  70.227 1.00 49.20  ? 684 GLU D N   1 
ATOM   13066 C CA  . GLU D 1 482 ? 30.945  24.172  71.188 1.00 50.68  ? 684 GLU D CA  1 
ATOM   13067 C C   . GLU D 1 482 ? 31.870  23.153  70.538 1.00 49.53  ? 684 GLU D C   1 
ATOM   13068 O O   . GLU D 1 482 ? 31.410  22.215  69.881 1.00 49.69  ? 684 GLU D O   1 
ATOM   13069 C CB  . GLU D 1 482 ? 30.286  23.588  72.435 1.00 51.89  ? 684 GLU D CB  1 
ATOM   13070 C CG  . GLU D 1 482 ? 31.256  23.162  73.517 1.00 61.47  ? 684 GLU D CG  1 
ATOM   13071 C CD  . GLU D 1 482 ? 30.542  22.675  74.758 1.00 68.18  ? 684 GLU D CD  1 
ATOM   13072 O OE1 . GLU D 1 482 ? 29.294  22.669  74.761 1.00 71.23  ? 684 GLU D OE1 1 
ATOM   13073 O OE2 . GLU D 1 482 ? 31.225  22.295  75.730 1.00 72.06  ? 684 GLU D OE2 1 
ATOM   13074 N N   . TRP D 1 483 ? 33.170  23.344  70.722 1.00 50.72  ? 685 TRP D N   1 
ATOM   13075 C CA  . TRP D 1 483 ? 34.194  22.516  70.110 1.00 50.37  ? 685 TRP D CA  1 
ATOM   13076 C C   . TRP D 1 483 ? 34.985  21.797  71.193 1.00 51.31  ? 685 TRP D C   1 
ATOM   13077 O O   . TRP D 1 483 ? 35.029  22.225  72.348 1.00 51.22  ? 685 TRP D O   1 
ATOM   13078 C CB  . TRP D 1 483 ? 35.131  23.369  69.248 1.00 44.98  ? 685 TRP D CB  1 
ATOM   13079 C CG  . TRP D 1 483 ? 34.444  24.020  68.087 1.00 43.98  ? 685 TRP D CG  1 
ATOM   13080 C CD1 . TRP D 1 483 ? 33.822  25.230  68.087 1.00 43.91  ? 685 TRP D CD1 1 
ATOM   13081 C CD2 . TRP D 1 483 ? 34.336  23.515  66.750 1.00 43.29  ? 685 TRP D CD2 1 
ATOM   13082 N NE1 . TRP D 1 483 ? 33.316  25.504  66.841 1.00 42.98  ? 685 TRP D NE1 1 
ATOM   13083 C CE2 . TRP D 1 483 ? 33.621  24.466  66.001 1.00 43.58  ? 685 TRP D CE2 1 
ATOM   13084 C CE3 . TRP D 1 483 ? 34.775  22.353  66.114 1.00 43.48  ? 685 TRP D CE3 1 
ATOM   13085 C CZ2 . TRP D 1 483 ? 33.331  24.287  64.653 1.00 43.81  ? 685 TRP D CZ2 1 
ATOM   13086 C CZ3 . TRP D 1 483 ? 34.484  22.177  64.779 1.00 43.77  ? 685 TRP D CZ3 1 
ATOM   13087 C CH2 . TRP D 1 483 ? 33.769  23.136  64.063 1.00 44.41  ? 685 TRP D CH2 1 
ATOM   13088 N N   . GLU D 1 484 ? 35.601  20.684  70.811 1.00 51.06  ? 686 GLU D N   1 
ATOM   13089 C CA  . GLU D 1 484 ? 36.485  19.938  71.695 1.00 52.75  ? 686 GLU D CA  1 
ATOM   13090 C C   . GLU D 1 484 ? 37.863  19.870  71.060 1.00 51.41  ? 686 GLU D C   1 
ATOM   13091 O O   . GLU D 1 484 ? 37.991  19.499  69.891 1.00 50.35  ? 686 GLU D O   1 
ATOM   13092 C CB  . GLU D 1 484 ? 35.951  18.531  71.960 1.00 49.65  ? 686 GLU D CB  1 
ATOM   13093 C CG  . GLU D 1 484 ? 36.800  17.722  72.923 1.00 58.38  ? 686 GLU D CG  1 
ATOM   13094 C CD  . GLU D 1 484 ? 36.226  16.346  73.193 1.00 64.22  ? 686 GLU D CD  1 
ATOM   13095 O OE1 . GLU D 1 484 ? 35.181  16.011  72.599 1.00 66.02  ? 686 GLU D OE1 1 
ATOM   13096 O OE2 . GLU D 1 484 ? 36.820  15.597  73.997 1.00 65.99  ? 686 GLU D OE2 1 
ATOM   13097 N N   . LEU D 1 485 ? 38.888  20.224  71.828 1.00 50.34  ? 687 LEU D N   1 
ATOM   13098 C CA  . LEU D 1 485 ? 40.258  20.264  71.341 1.00 51.01  ? 687 LEU D CA  1 
ATOM   13099 C C   . LEU D 1 485 ? 41.039  19.072  71.872 1.00 53.89  ? 687 LEU D C   1 
ATOM   13100 O O   . LEU D 1 485 ? 40.784  18.593  72.980 1.00 54.59  ? 687 LEU D O   1 
ATOM   13101 C CB  . LEU D 1 485 ? 40.959  21.554  71.765 1.00 53.57  ? 687 LEU D CB  1 
ATOM   13102 C CG  . LEU D 1 485 ? 40.410  22.874  71.237 1.00 51.48  ? 687 LEU D CG  1 
ATOM   13103 C CD1 . LEU D 1 485 ? 41.195  24.019  71.846 1.00 50.41  ? 687 LEU D CD1 1 
ATOM   13104 C CD2 . LEU D 1 485 ? 40.477  22.917  69.725 1.00 50.82  ? 687 LEU D CD2 1 
ATOM   13105 N N   . GLN D 1 486 ? 41.989  18.600  71.076 1.00 48.47  ? 688 GLN D N   1 
ATOM   13106 C CA  . GLN D 1 486 ? 42.878  17.534  71.509 1.00 51.78  ? 688 GLN D CA  1 
ATOM   13107 C C   . GLN D 1 486 ? 44.282  18.073  71.765 1.00 53.84  ? 688 GLN D C   1 
ATOM   13108 O O   . GLN D 1 486 ? 44.601  19.205  71.404 1.00 54.63  ? 688 GLN D O   1 
ATOM   13109 C CB  . GLN D 1 486 ? 42.925  16.416  70.471 1.00 51.04  ? 688 GLN D CB  1 
ATOM   13110 C CG  . GLN D 1 486 ? 43.709  15.206  70.926 1.00 56.64  ? 688 GLN D CG  1 
ATOM   13111 C CD  . GLN D 1 486 ? 43.632  14.064  69.941 1.00 61.73  ? 688 GLN D CD  1 
ATOM   13112 O OE1 . GLN D 1 486 ? 42.923  14.143  68.939 1.00 64.33  ? 688 GLN D OE1 1 
ATOM   13113 N NE2 . GLN D 1 486 ? 44.363  12.991  70.219 1.00 62.92  ? 688 GLN D NE2 1 
ATOM   13114 N N   . PHE E 1 215 ? 47.626  -5.593  76.697 1.00 54.64  ? 417 PHE E N   1 
ATOM   13115 C CA  . PHE E 1 215 ? 47.247  -5.667  75.291 1.00 54.57  ? 417 PHE E CA  1 
ATOM   13116 C C   . PHE E 1 215 ? 45.817  -5.203  75.068 1.00 57.33  ? 417 PHE E C   1 
ATOM   13117 O O   . PHE E 1 215 ? 44.902  -5.607  75.783 1.00 56.90  ? 417 PHE E O   1 
ATOM   13118 C CB  . PHE E 1 215 ? 47.406  -7.093  74.761 1.00 55.74  ? 417 PHE E CB  1 
ATOM   13119 C CG  . PHE E 1 215 ? 48.826  -7.569  74.714 1.00 52.74  ? 417 PHE E CG  1 
ATOM   13120 C CD1 . PHE E 1 215 ? 49.631  -7.275  73.629 1.00 51.18  ? 417 PHE E CD1 1 
ATOM   13121 C CD2 . PHE E 1 215 ? 49.354  -8.314  75.751 1.00 51.94  ? 417 PHE E CD2 1 
ATOM   13122 C CE1 . PHE E 1 215 ? 50.938  -7.714  73.581 1.00 50.10  ? 417 PHE E CE1 1 
ATOM   13123 C CE2 . PHE E 1 215 ? 50.661  -8.754  75.708 1.00 50.40  ? 417 PHE E CE2 1 
ATOM   13124 C CZ  . PHE E 1 215 ? 51.453  -8.454  74.622 1.00 50.21  ? 417 PHE E CZ  1 
ATOM   13125 N N   . GLU E 1 216 ? 45.631  -4.346  74.071 1.00 53.85  ? 418 GLU E N   1 
ATOM   13126 C CA  . GLU E 1 216 ? 44.293  -3.939  73.683 1.00 57.93  ? 418 GLU E CA  1 
ATOM   13127 C C   . GLU E 1 216 ? 43.610  -5.059  72.906 1.00 57.98  ? 418 GLU E C   1 
ATOM   13128 O O   . GLU E 1 216 ? 44.258  -5.936  72.329 1.00 57.57  ? 418 GLU E O   1 
ATOM   13129 C CB  . GLU E 1 216 ? 44.337  -2.661  72.850 1.00 51.44  ? 418 GLU E CB  1 
ATOM   13130 C CG  . GLU E 1 216 ? 45.118  -2.783  71.560 1.00 58.69  ? 418 GLU E CG  1 
ATOM   13131 C CD  . GLU E 1 216 ? 45.209  -1.466  70.824 1.00 63.74  ? 418 GLU E CD  1 
ATOM   13132 O OE1 . GLU E 1 216 ? 44.400  -0.565  71.124 1.00 67.11  ? 418 GLU E OE1 1 
ATOM   13133 O OE2 . GLU E 1 216 ? 46.088  -1.327  69.952 1.00 65.50  ? 418 GLU E OE2 1 
ATOM   13134 N N   . ASN E 1 217 ? 42.281  -5.022  72.908 1.00 59.11  ? 419 ASN E N   1 
ATOM   13135 C CA  . ASN E 1 217 ? 41.493  -6.084  72.299 1.00 60.28  ? 419 ASN E CA  1 
ATOM   13136 C C   . ASN E 1 217 ? 41.831  -6.227  70.822 1.00 59.05  ? 419 ASN E C   1 
ATOM   13137 O O   . ASN E 1 217 ? 41.722  -5.267  70.054 1.00 59.60  ? 419 ASN E O   1 
ATOM   13138 C CB  . ASN E 1 217 ? 40.006  -5.785  72.479 1.00 60.58  ? 419 ASN E CB  1 
ATOM   13139 C CG  . ASN E 1 217 ? 39.122  -6.947  72.084 1.00 65.98  ? 419 ASN E CG  1 
ATOM   13140 O OD1 . ASN E 1 217 ? 39.512  -8.108  72.201 1.00 68.96  ? 419 ASN E OD1 1 
ATOM   13141 N ND2 . ASN E 1 217 ? 37.920  -6.639  71.613 1.00 68.32  ? 419 ASN E ND2 1 
ATOM   13142 N N   . VAL E 1 218 ? 42.238  -7.429  70.429 1.00 58.89  ? 420 VAL E N   1 
ATOM   13143 C CA  . VAL E 1 218 ? 42.525  -7.745  69.031 1.00 57.36  ? 420 VAL E CA  1 
ATOM   13144 C C   . VAL E 1 218 ? 41.903  -9.098  68.720 1.00 56.00  ? 420 VAL E C   1 
ATOM   13145 O O   . VAL E 1 218 ? 41.735  -9.942  69.615 1.00 56.00  ? 420 VAL E O   1 
ATOM   13146 C CB  . VAL E 1 218 ? 44.045  -7.754  68.741 1.00 53.68  ? 420 VAL E CB  1 
ATOM   13147 C CG1 . VAL E 1 218 ? 44.644  -6.374  68.949 1.00 56.65  ? 420 VAL E CG1 1 
ATOM   13148 C CG2 . VAL E 1 218 ? 44.749  -8.786  69.603 1.00 54.82  ? 420 VAL E CG2 1 
ATOM   13149 N N   . PRO E 1 219 ? 41.537  -9.333  67.463 1.00 55.04  ? 421 PRO E N   1 
ATOM   13150 C CA  . PRO E 1 219 ? 40.958  -10.629 67.106 1.00 53.76  ? 421 PRO E CA  1 
ATOM   13151 C C   . PRO E 1 219 ? 41.981  -11.742 67.235 1.00 53.02  ? 421 PRO E C   1 
ATOM   13152 O O   . PRO E 1 219 ? 43.189  -11.526 67.110 1.00 53.63  ? 421 PRO E O   1 
ATOM   13153 C CB  . PRO E 1 219 ? 40.529  -10.433 65.649 1.00 53.61  ? 421 PRO E CB  1 
ATOM   13154 C CG  . PRO E 1 219 ? 41.449  -9.380  65.140 1.00 54.18  ? 421 PRO E CG  1 
ATOM   13155 C CD  . PRO E 1 219 ? 41.646  -8.445  66.293 1.00 53.89  ? 421 PRO E CD  1 
ATOM   13156 N N   . PHE E 1 220 ? 41.483  -12.944 67.509 1.00 48.51  ? 422 PHE E N   1 
ATOM   13157 C CA  . PHE E 1 220 ? 42.338  -14.121 67.509 1.00 46.53  ? 422 PHE E CA  1 
ATOM   13158 C C   . PHE E 1 220 ? 42.969  -14.294 66.138 1.00 46.20  ? 422 PHE E C   1 
ATOM   13159 O O   . PHE E 1 220 ? 42.279  -14.229 65.117 1.00 46.14  ? 422 PHE E O   1 
ATOM   13160 C CB  . PHE E 1 220 ? 41.536  -15.374 67.858 1.00 41.30  ? 422 PHE E CB  1 
ATOM   13161 C CG  . PHE E 1 220 ? 40.989  -15.388 69.253 1.00 42.95  ? 422 PHE E CG  1 
ATOM   13162 C CD1 . PHE E 1 220 ? 41.761  -15.839 70.307 1.00 42.91  ? 422 PHE E CD1 1 
ATOM   13163 C CD2 . PHE E 1 220 ? 39.698  -14.968 69.508 1.00 42.98  ? 422 PHE E CD2 1 
ATOM   13164 C CE1 . PHE E 1 220 ? 41.260  -15.864 71.590 1.00 42.75  ? 422 PHE E CE1 1 
ATOM   13165 C CE2 . PHE E 1 220 ? 39.190  -14.991 70.791 1.00 42.14  ? 422 PHE E CE2 1 
ATOM   13166 C CZ  . PHE E 1 220 ? 39.972  -15.440 71.833 1.00 42.40  ? 422 PHE E CZ  1 
ATOM   13167 N N   . HIS E 1 221 ? 44.260  -14.584 66.089 1.00 45.02  ? 423 HIS E N   1 
ATOM   13168 C CA  . HIS E 1 221 ? 44.861  -14.879 64.804 1.00 45.16  ? 423 HIS E CA  1 
ATOM   13169 C C   . HIS E 1 221 ? 44.332  -16.274 64.532 1.00 45.85  ? 423 HIS E C   1 
ATOM   13170 O O   . HIS E 1 221 ? 44.398  -17.129 65.407 1.00 46.03  ? 423 HIS E O   1 
ATOM   13171 C CB  . HIS E 1 221 ? 46.376  -14.921 64.886 1.00 40.83  ? 423 HIS E CB  1 
ATOM   13172 C CG  . HIS E 1 221 ? 47.012  -15.645 63.744 1.00 42.49  ? 423 HIS E CG  1 
ATOM   13173 N ND1 . HIS E 1 221 ? 47.437  -15.005 62.602 1.00 43.59  ? 423 HIS E ND1 1 
ATOM   13174 C CD2 . HIS E 1 221 ? 47.278  -16.959 63.559 1.00 42.82  ? 423 HIS E CD2 1 
ATOM   13175 C CE1 . HIS E 1 221 ? 47.950  -15.891 61.767 1.00 44.21  ? 423 HIS E CE1 1 
ATOM   13176 N NE2 . HIS E 1 221 ? 47.865  -17.084 62.325 1.00 44.06  ? 423 HIS E NE2 1 
ATOM   13177 N N   . SER E 1 222 ? 43.816  -16.528 63.336 1.00 44.90  ? 424 SER E N   1 
ATOM   13178 C CA  . SER E 1 222 ? 43.252  -17.844 63.065 1.00 45.22  ? 424 SER E CA  1 
ATOM   13179 C C   . SER E 1 222 ? 44.255  -18.816 62.489 1.00 44.65  ? 424 SER E C   1 
ATOM   13180 O O   . SER E 1 222 ? 44.593  -18.746 61.315 1.00 45.32  ? 424 SER E O   1 
ATOM   13181 C CB  . SER E 1 222 ? 42.098  -17.716 62.085 1.00 44.15  ? 424 SER E CB  1 
ATOM   13182 O OG  . SER E 1 222 ? 42.585  -17.460 60.784 1.00 47.74  ? 424 SER E OG  1 
ATOM   13183 N N   . SER E 1 223 ? 44.707  -19.741 63.328 1.00 42.60  ? 425 SER E N   1 
ATOM   13184 C CA  . SER E 1 223 ? 45.667  -20.754 62.922 1.00 42.25  ? 425 SER E CA  1 
ATOM   13185 C C   . SER E 1 223 ? 45.005  -22.019 62.402 1.00 41.42  ? 425 SER E C   1 
ATOM   13186 O O   . SER E 1 223 ? 45.013  -23.042 63.074 1.00 42.13  ? 425 SER E O   1 
ATOM   13187 C CB  . SER E 1 223 ? 46.598  -21.090 64.083 1.00 44.20  ? 425 SER E CB  1 
ATOM   13188 O OG  . SER E 1 223 ? 45.870  -21.602 65.179 1.00 46.35  ? 425 SER E OG  1 
ATOM   13189 N N   . TYR E 1 224 ? 44.422  -21.945 61.216 1.00 42.53  ? 426 TYR E N   1 
ATOM   13190 C CA  . TYR E 1 224 ? 43.778  -23.101 60.612 1.00 42.97  ? 426 TYR E CA  1 
ATOM   13191 C C   . TYR E 1 224 ? 43.679  -22.916 59.112 1.00 42.90  ? 426 TYR E C   1 
ATOM   13192 O O   . TYR E 1 224 ? 43.815  -21.811 58.608 1.00 43.27  ? 426 TYR E O   1 
ATOM   13193 C CB  . TYR E 1 224 ? 42.389  -23.324 61.199 1.00 38.42  ? 426 TYR E CB  1 
ATOM   13194 C CG  . TYR E 1 224 ? 41.452  -22.178 60.953 1.00 39.80  ? 426 TYR E CG  1 
ATOM   13195 C CD1 . TYR E 1 224 ? 41.107  -21.808 59.666 1.00 40.26  ? 426 TYR E CD1 1 
ATOM   13196 C CD2 . TYR E 1 224 ? 40.913  -21.465 62.005 1.00 40.60  ? 426 TYR E CD2 1 
ATOM   13197 C CE1 . TYR E 1 224 ? 40.255  -20.757 59.435 1.00 42.58  ? 426 TYR E CE1 1 
ATOM   13198 C CE2 . TYR E 1 224 ? 40.056  -20.415 61.783 1.00 42.60  ? 426 TYR E CE2 1 
ATOM   13199 C CZ  . TYR E 1 224 ? 39.732  -20.066 60.495 1.00 43.47  ? 426 TYR E CZ  1 
ATOM   13200 O OH  . TYR E 1 224 ? 38.878  -19.017 60.276 1.00 44.78  ? 426 TYR E OH  1 
ATOM   13201 N N   . ALA E 1 225 ? 43.447  -24.004 58.398 1.00 41.04  ? 427 ALA E N   1 
ATOM   13202 C CA  . ALA E 1 225 ? 43.300  -23.941 56.959 1.00 41.01  ? 427 ALA E CA  1 
ATOM   13203 C C   . ALA E 1 225 ? 41.886  -24.387 56.643 1.00 41.70  ? 427 ALA E C   1 
ATOM   13204 O O   . ALA E 1 225 ? 41.428  -25.390 57.169 1.00 42.36  ? 427 ALA E O   1 
ATOM   13205 C CB  . ALA E 1 225 ? 44.310  -24.851 56.289 1.00 46.77  ? 427 ALA E CB  1 
ATOM   13206 N N   . HIS E 1 226 ? 41.175  -23.640 55.815 1.00 40.44  ? 428 HIS E N   1 
ATOM   13207 C CA  . HIS E 1 226 ? 39.814  -24.028 55.485 1.00 40.48  ? 428 HIS E CA  1 
ATOM   13208 C C   . HIS E 1 226 ? 39.796  -25.344 54.727 1.00 40.94  ? 428 HIS E C   1 
ATOM   13209 O O   . HIS E 1 226 ? 40.617  -25.571 53.845 1.00 39.65  ? 428 HIS E O   1 
ATOM   13210 C CB  . HIS E 1 226 ? 39.125  -22.938 54.672 1.00 36.35  ? 428 HIS E CB  1 
ATOM   13211 C CG  . HIS E 1 226 ? 38.925  -21.666 55.430 1.00 37.49  ? 428 HIS E CG  1 
ATOM   13212 N ND1 . HIS E 1 226 ? 37.970  -21.531 56.412 1.00 37.07  ? 428 HIS E ND1 1 
ATOM   13213 C CD2 . HIS E 1 226 ? 39.563  -20.477 55.359 1.00 38.11  ? 428 HIS E CD2 1 
ATOM   13214 C CE1 . HIS E 1 226 ? 38.023  -20.310 56.909 1.00 37.49  ? 428 HIS E CE1 1 
ATOM   13215 N NE2 . HIS E 1 226 ? 38.983  -19.651 56.289 1.00 39.12  ? 428 HIS E NE2 1 
ATOM   13216 N N   . SER E 1 227 ? 38.860  -26.215 55.087 1.00 42.00  ? 429 SER E N   1 
ATOM   13217 C CA  . SER E 1 227 ? 38.720  -27.506 54.432 1.00 43.06  ? 429 SER E CA  1 
ATOM   13218 C C   . SER E 1 227 ? 37.827  -27.403 53.199 1.00 43.24  ? 429 SER E C   1 
ATOM   13219 O O   . SER E 1 227 ? 37.736  -28.337 52.409 1.00 43.78  ? 429 SER E O   1 
ATOM   13220 C CB  . SER E 1 227 ? 38.173  -28.544 55.406 1.00 42.39  ? 429 SER E CB  1 
ATOM   13221 O OG  . SER E 1 227 ? 36.909  -28.155 55.897 1.00 46.51  ? 429 SER E OG  1 
ATOM   13222 N N   . GLN E 1 228 ? 37.176  -26.257 53.041 1.00 38.04  ? 430 GLN E N   1 
ATOM   13223 C CA  . GLN E 1 228 ? 36.301  -26.002 51.911 1.00 39.34  ? 430 GLN E CA  1 
ATOM   13224 C C   . GLN E 1 228 ? 36.840  -24.823 51.126 1.00 38.94  ? 430 GLN E C   1 
ATOM   13225 O O   . GLN E 1 228 ? 37.609  -24.026 51.655 1.00 38.80  ? 430 GLN E O   1 
ATOM   13226 C CB  . GLN E 1 228 ? 34.900  -25.660 52.402 1.00 40.93  ? 430 GLN E CB  1 
ATOM   13227 C CG  . GLN E 1 228 ? 34.010  -26.849 52.701 1.00 41.68  ? 430 GLN E CG  1 
ATOM   13228 C CD  . GLN E 1 228 ? 32.593  -26.423 53.026 1.00 42.22  ? 430 GLN E CD  1 
ATOM   13229 O OE1 . GLN E 1 228 ? 32.357  -25.721 54.004 1.00 42.99  ? 430 GLN E OE1 1 
ATOM   13230 N NE2 . GLN E 1 228 ? 31.643  -26.843 52.203 1.00 40.24  ? 430 GLN E NE2 1 
ATOM   13231 N N   . SER E 1 229 ? 36.440  -24.710 49.864 1.00 37.02  ? 431 SER E N   1 
ATOM   13232 C CA  . SER E 1 229 ? 36.870  -23.600 49.030 1.00 36.84  ? 431 SER E CA  1 
ATOM   13233 C C   . SER E 1 229 ? 35.701  -22.656 48.791 1.00 36.58  ? 431 SER E C   1 
ATOM   13234 O O   . SER E 1 229 ? 34.534  -23.035 48.918 1.00 35.87  ? 431 SER E O   1 
ATOM   13235 C CB  . SER E 1 229 ? 37.431  -24.086 47.694 1.00 38.12  ? 431 SER E CB  1 
ATOM   13236 O OG  . SER E 1 229 ? 36.426  -24.698 46.912 1.00 42.60  ? 431 SER E OG  1 
ATOM   13237 N N   . LEU E 1 230 ? 36.034  -21.410 48.453 1.00 35.37  ? 432 LEU E N   1 
ATOM   13238 C CA  . LEU E 1 230 ? 35.029  -20.357 48.371 1.00 34.76  ? 432 LEU E CA  1 
ATOM   13239 C C   . LEU E 1 230 ? 33.969  -20.657 47.321 1.00 35.69  ? 432 LEU E C   1 
ATOM   13240 O O   . LEU E 1 230 ? 32.800  -20.295 47.502 1.00 35.99  ? 432 LEU E O   1 
ATOM   13241 C CB  . LEU E 1 230 ? 35.708  -19.026 48.061 1.00 32.63  ? 432 LEU E CB  1 
ATOM   13242 C CG  . LEU E 1 230 ? 34.896  -17.744 48.201 1.00 33.37  ? 432 LEU E CG  1 
ATOM   13243 C CD1 . LEU E 1 230 ? 33.915  -17.871 49.347 1.00 33.05  ? 432 LEU E CD1 1 
ATOM   13244 C CD2 . LEU E 1 230 ? 35.832  -16.592 48.454 1.00 33.75  ? 432 LEU E CD2 1 
ATOM   13245 N N   . ASP E 1 231 ? 34.346  -21.298 46.220 1.00 34.76  ? 433 ASP E N   1 
ATOM   13246 C CA  . ASP E 1 231 ? 33.417  -21.535 45.127 1.00 36.83  ? 433 ASP E CA  1 
ATOM   13247 C C   . ASP E 1 231 ? 32.665  -22.859 45.229 1.00 36.15  ? 433 ASP E C   1 
ATOM   13248 O O   . ASP E 1 231 ? 31.681  -23.048 44.509 1.00 37.22  ? 433 ASP E O   1 
ATOM   13249 C CB  . ASP E 1 231 ? 34.167  -21.459 43.792 1.00 35.32  ? 433 ASP E CB  1 
ATOM   13250 C CG  . ASP E 1 231 ? 35.348  -22.397 43.733 1.00 39.55  ? 433 ASP E CG  1 
ATOM   13251 O OD1 . ASP E 1 231 ? 35.667  -23.021 44.765 1.00 41.60  ? 433 ASP E OD1 1 
ATOM   13252 O OD2 . ASP E 1 231 ? 35.969  -22.507 42.657 1.00 42.99  ? 433 ASP E OD2 1 
ATOM   13253 N N   . ARG E 1 232 ? 33.093  -23.770 46.100 1.00 37.69  ? 434 ARG E N   1 
ATOM   13254 C CA  . ARG E 1 232 ? 32.487  -25.091 46.233 1.00 36.03  ? 434 ARG E CA  1 
ATOM   13255 C C   . ARG E 1 232 ? 31.504  -25.215 47.394 1.00 35.75  ? 434 ARG E C   1 
ATOM   13256 O O   . ARG E 1 232 ? 31.107  -26.333 47.730 1.00 35.59  ? 434 ARG E O   1 
ATOM   13257 C CB  . ARG E 1 232 ? 33.574  -26.160 46.316 1.00 38.89  ? 434 ARG E CB  1 
ATOM   13258 C CG  . ARG E 1 232 ? 34.326  -26.293 45.005 1.00 40.93  ? 434 ARG E CG  1 
ATOM   13259 C CD  . ARG E 1 232 ? 33.399  -26.893 43.959 1.00 39.54  ? 434 ARG E CD  1 
ATOM   13260 N NE  . ARG E 1 232 ? 34.006  -27.027 42.639 1.00 39.46  ? 434 ARG E NE  1 
ATOM   13261 C CZ  . ARG E 1 232 ? 33.878  -26.134 41.663 1.00 39.42  ? 434 ARG E CZ  1 
ATOM   13262 N NH1 . ARG E 1 232 ? 33.159  -25.039 41.851 1.00 38.30  ? 434 ARG E NH1 1 
ATOM   13263 N NH2 . ARG E 1 232 ? 34.460  -26.343 40.493 1.00 41.47  ? 434 ARG E NH2 1 
ATOM   13264 N N   . LEU E 1 233 ? 31.130  -24.109 48.040 1.00 32.97  ? 435 LEU E N   1 
ATOM   13265 C CA  . LEU E 1 233 ? 30.293  -24.158 49.238 1.00 32.83  ? 435 LEU E CA  1 
ATOM   13266 C C   . LEU E 1 233 ? 28.907  -24.757 49.001 1.00 33.63  ? 435 LEU E C   1 
ATOM   13267 O O   . LEU E 1 233 ? 28.162  -24.949 49.967 1.00 34.50  ? 435 LEU E O   1 
ATOM   13268 C CB  . LEU E 1 233 ? 30.149  -22.752 49.820 1.00 32.80  ? 435 LEU E CB  1 
ATOM   13269 C CG  . LEU E 1 233 ? 31.452  -22.111 50.291 1.00 33.33  ? 435 LEU E CG  1 
ATOM   13270 C CD1 . LEU E 1 233 ? 31.226  -20.682 50.743 1.00 31.17  ? 435 LEU E CD1 1 
ATOM   13271 C CD2 . LEU E 1 233 ? 32.067  -22.931 51.404 1.00 32.80  ? 435 LEU E CD2 1 
ATOM   13272 N N   . MET E 1 234 ? 28.546  -25.047 47.759 1.00 34.41  ? 436 MET E N   1 
ATOM   13273 C CA  . MET E 1 234 ? 27.242  -25.567 47.376 1.00 35.47  ? 436 MET E CA  1 
ATOM   13274 C C   . MET E 1 234 ? 27.014  -26.995 47.874 1.00 35.57  ? 436 MET E C   1 
ATOM   13275 O O   . MET E 1 234 ? 27.945  -27.716 48.241 1.00 35.54  ? 436 MET E O   1 
ATOM   13276 C CB  . MET E 1 234 ? 27.116  -25.557 45.860 1.00 35.17  ? 436 MET E CB  1 
ATOM   13277 C CG  . MET E 1 234 ? 28.083  -26.528 45.228 1.00 37.22  ? 436 MET E CG  1 
ATOM   13278 S SD  . MET E 1 234 ? 28.264  -26.303 43.465 1.00 41.85  ? 436 MET E SD  1 
ATOM   13279 C CE  . MET E 1 234 ? 29.493  -25.009 43.436 1.00 41.23  ? 436 MET E CE  1 
ATOM   13280 N N   . ASN E 1 235 ? 25.743  -27.389 47.888 1.00 35.70  ? 437 ASN E N   1 
ATOM   13281 C CA  . ASN E 1 235 ? 25.366  -28.796 47.992 1.00 34.39  ? 437 ASN E CA  1 
ATOM   13282 C C   . ASN E 1 235 ? 25.479  -29.439 46.614 1.00 33.71  ? 437 ASN E C   1 
ATOM   13283 O O   . ASN E 1 235 ? 24.818  -28.982 45.675 1.00 34.06  ? 437 ASN E O   1 
ATOM   13284 C CB  . ASN E 1 235 ? 23.940  -28.928 48.525 1.00 35.00  ? 437 ASN E CB  1 
ATOM   13285 C CG  . ASN E 1 235 ? 23.536  -30.371 48.816 1.00 35.53  ? 437 ASN E CG  1 
ATOM   13286 O OD1 . ASN E 1 235 ? 24.122  -31.317 48.299 1.00 35.83  ? 437 ASN E OD1 1 
ATOM   13287 N ND2 . ASN E 1 235 ? 22.515  -30.537 49.646 1.00 35.23  ? 437 ASN E ND2 1 
ATOM   13288 N N   . PRO E 1 236 ? 26.298  -30.480 46.445 1.00 34.62  ? 438 PRO E N   1 
ATOM   13289 C CA  . PRO E 1 236 ? 26.484  -31.066 45.110 1.00 33.95  ? 438 PRO E CA  1 
ATOM   13290 C C   . PRO E 1 236 ? 25.278  -31.818 44.576 1.00 34.12  ? 438 PRO E C   1 
ATOM   13291 O O   . PRO E 1 236 ? 25.277  -32.160 43.391 1.00 34.73  ? 438 PRO E O   1 
ATOM   13292 C CB  . PRO E 1 236 ? 27.671  -32.012 45.311 1.00 33.45  ? 438 PRO E CB  1 
ATOM   13293 C CG  . PRO E 1 236 ? 27.592  -32.390 46.741 1.00 33.96  ? 438 PRO E CG  1 
ATOM   13294 C CD  . PRO E 1 236 ? 27.116  -31.161 47.461 1.00 34.05  ? 438 PRO E CD  1 
ATOM   13295 N N   . LEU E 1 237 ? 24.294  -32.154 45.407 1.00 33.80  ? 439 LEU E N   1 
ATOM   13296 C CA  . LEU E 1 237 ? 23.213  -33.027 44.968 1.00 33.12  ? 439 LEU E CA  1 
ATOM   13297 C C   . LEU E 1 237 ? 21.965  -32.297 44.482 1.00 34.55  ? 439 LEU E C   1 
ATOM   13298 O O   . LEU E 1 237 ? 21.086  -32.940 43.900 1.00 34.97  ? 439 LEU E O   1 
ATOM   13299 C CB  . LEU E 1 237 ? 22.830  -33.977 46.106 1.00 35.87  ? 439 LEU E CB  1 
ATOM   13300 C CG  . LEU E 1 237 ? 23.938  -34.942 46.524 1.00 35.15  ? 439 LEU E CG  1 
ATOM   13301 C CD1 . LEU E 1 237 ? 23.541  -35.678 47.779 1.00 33.08  ? 439 LEU E CD1 1 
ATOM   13302 C CD2 . LEU E 1 237 ? 24.238  -35.918 45.404 1.00 32.71  ? 439 LEU E CD2 1 
ATOM   13303 N N   . ILE E 1 238 ? 21.858  -30.986 44.685 1.00 32.60  ? 440 ILE E N   1 
ATOM   13304 C CA  . ILE E 1 238 ? 20.615  -30.271 44.419 1.00 33.65  ? 440 ILE E CA  1 
ATOM   13305 C C   . ILE E 1 238 ? 20.891  -29.108 43.476 1.00 35.51  ? 440 ILE E C   1 
ATOM   13306 O O   . ILE E 1 238 ? 21.940  -28.461 43.546 1.00 36.82  ? 440 ILE E O   1 
ATOM   13307 C CB  . ILE E 1 238 ? 19.954  -29.765 45.723 1.00 32.43  ? 440 ILE E CB  1 
ATOM   13308 C CG1 . ILE E 1 238 ? 19.761  -30.908 46.717 1.00 30.37  ? 440 ILE E CG1 1 
ATOM   13309 C CG2 . ILE E 1 238 ? 18.601  -29.147 45.431 1.00 32.09  ? 440 ILE E CG2 1 
ATOM   13310 C CD1 . ILE E 1 238 ? 18.869  -32.009 46.214 1.00 27.86  ? 440 ILE E CD1 1 
ATOM   13311 N N   . ASP E 1 239 ? 19.933  -28.842 42.592 1.00 31.12  ? 441 ASP E N   1 
ATOM   13312 C CA  . ASP E 1 239 ? 20.015  -27.734 41.653 1.00 32.23  ? 441 ASP E CA  1 
ATOM   13313 C C   . ASP E 1 239 ? 19.796  -26.403 42.358 1.00 30.85  ? 441 ASP E C   1 
ATOM   13314 O O   . ASP E 1 239 ? 19.260  -26.334 43.466 1.00 31.82  ? 441 ASP E O   1 
ATOM   13315 C CB  . ASP E 1 239 ? 18.963  -27.868 40.556 1.00 34.45  ? 441 ASP E CB  1 
ATOM   13316 C CG  . ASP E 1 239 ? 19.198  -29.050 39.661 1.00 40.96  ? 441 ASP E CG  1 
ATOM   13317 O OD1 . ASP E 1 239 ? 20.320  -29.587 39.645 1.00 47.58  ? 441 ASP E OD1 1 
ATOM   13318 O OD2 . ASP E 1 239 ? 18.241  -29.454 38.974 1.00 42.51  ? 441 ASP E OD2 1 
ATOM   13319 N N   . GLN E 1 240 ? 20.225  -25.334 41.698 1.00 27.14  ? 442 GLN E N   1 
ATOM   13320 C CA  . GLN E 1 240 ? 19.774  -23.992 42.028 1.00 25.90  ? 442 GLN E CA  1 
ATOM   13321 C C   . GLN E 1 240 ? 18.532  -23.637 41.221 1.00 25.78  ? 442 GLN E C   1 
ATOM   13322 O O   . GLN E 1 240 ? 18.386  -24.029 40.063 1.00 25.75  ? 442 GLN E O   1 
ATOM   13323 C CB  . GLN E 1 240 ? 20.859  -22.944 41.777 1.00 27.45  ? 442 GLN E CB  1 
ATOM   13324 C CG  . GLN E 1 240 ? 22.006  -22.958 42.771 1.00 25.69  ? 442 GLN E CG  1 
ATOM   13325 C CD  . GLN E 1 240 ? 22.987  -21.838 42.518 1.00 25.82  ? 442 GLN E CD  1 
ATOM   13326 O OE1 . GLN E 1 240 ? 23.111  -21.353 41.399 1.00 24.73  ? 442 GLN E OE1 1 
ATOM   13327 N NE2 . GLN E 1 240 ? 23.666  -21.397 43.565 1.00 25.94  ? 442 GLN E NE2 1 
ATOM   13328 N N   . TYR E 1 241 ? 17.629  -22.889 41.856 1.00 20.45  ? 443 TYR E N   1 
ATOM   13329 C CA  . TYR E 1 241 ? 16.474  -22.357 41.141 1.00 19.01  ? 443 TYR E CA  1 
ATOM   13330 C C   . TYR E 1 241 ? 16.859  -21.168 40.268 1.00 18.64  ? 443 TYR E C   1 
ATOM   13331 O O   . TYR E 1 241 ? 16.020  -20.621 39.545 1.00 19.92  ? 443 TYR E O   1 
ATOM   13332 C CB  . TYR E 1 241 ? 15.372  -21.986 42.133 1.00 20.10  ? 443 TYR E CB  1 
ATOM   13333 C CG  . TYR E 1 241 ? 15.809  -21.093 43.270 1.00 19.66  ? 443 TYR E CG  1 
ATOM   13334 C CD1 . TYR E 1 241 ? 15.838  -19.716 43.134 1.00 19.26  ? 443 TYR E CD1 1 
ATOM   13335 C CD2 . TYR E 1 241 ? 16.167  -21.632 44.495 1.00 20.53  ? 443 TYR E CD2 1 
ATOM   13336 C CE1 . TYR E 1 241 ? 16.234  -18.904 44.179 1.00 19.42  ? 443 TYR E CE1 1 
ATOM   13337 C CE2 . TYR E 1 241 ? 16.560  -20.829 45.544 1.00 20.59  ? 443 TYR E CE2 1 
ATOM   13338 C CZ  . TYR E 1 241 ? 16.592  -19.468 45.379 1.00 20.21  ? 443 TYR E CZ  1 
ATOM   13339 O OH  . TYR E 1 241 ? 16.980  -18.667 46.422 1.00 20.04  ? 443 TYR E OH  1 
ATOM   13340 N N   . LEU E 1 242 ? 18.115  -20.737 40.348 1.00 18.37  ? 444 LEU E N   1 
ATOM   13341 C CA  . LEU E 1 242 ? 18.620  -19.682 39.482 1.00 18.52  ? 444 LEU E CA  1 
ATOM   13342 C C   . LEU E 1 242 ? 19.025  -20.234 38.119 1.00 19.13  ? 444 LEU E C   1 
ATOM   13343 O O   . LEU E 1 242 ? 19.322  -21.420 37.965 1.00 19.42  ? 444 LEU E O   1 
ATOM   13344 C CB  . LEU E 1 242 ? 19.807  -18.987 40.137 1.00 18.09  ? 444 LEU E CB  1 
ATOM   13345 C CG  . LEU E 1 242 ? 19.486  -18.294 41.455 1.00 17.51  ? 444 LEU E CG  1 
ATOM   13346 C CD1 . LEU E 1 242 ? 20.746  -17.704 42.029 1.00 16.78  ? 444 LEU E CD1 1 
ATOM   13347 C CD2 . LEU E 1 242 ? 18.428  -17.229 41.261 1.00 16.72  ? 444 LEU E CD2 1 
ATOM   13348 N N   . TYR E 1 243 ? 19.050  -19.349 37.127 1.00 18.61  ? 445 TYR E N   1 
ATOM   13349 C CA  . TYR E 1 243 ? 19.391  -19.673 35.750 1.00 18.63  ? 445 TYR E CA  1 
ATOM   13350 C C   . TYR E 1 243 ? 20.601  -18.881 35.274 1.00 18.66  ? 445 TYR E C   1 
ATOM   13351 O O   . TYR E 1 243 ? 20.960  -17.846 35.840 1.00 18.62  ? 445 TYR E O   1 
ATOM   13352 C CB  . TYR E 1 243 ? 18.203  -19.400 34.829 1.00 16.96  ? 445 TYR E CB  1 
ATOM   13353 C CG  . TYR E 1 243 ? 17.123  -20.438 34.919 1.00 19.15  ? 445 TYR E CG  1 
ATOM   13354 C CD1 . TYR E 1 243 ? 17.046  -21.453 33.984 1.00 20.34  ? 445 TYR E CD1 1 
ATOM   13355 C CD2 . TYR E 1 243 ? 16.221  -20.445 35.966 1.00 19.43  ? 445 TYR E CD2 1 
ATOM   13356 C CE1 . TYR E 1 243 ? 16.072  -22.412 34.054 1.00 21.10  ? 445 TYR E CE1 1 
ATOM   13357 C CE2 . TYR E 1 243 ? 15.245  -21.413 36.053 1.00 20.14  ? 445 TYR E CE2 1 
ATOM   13358 C CZ  . TYR E 1 243 ? 15.179  -22.394 35.092 1.00 20.84  ? 445 TYR E CZ  1 
ATOM   13359 O OH  . TYR E 1 243 ? 14.213  -23.365 35.162 1.00 21.98  ? 445 TYR E OH  1 
ATOM   13360 N N   . TYR E 1 244 ? 21.234  -19.393 34.219 1.00 17.08  ? 446 TYR E N   1 
ATOM   13361 C CA  . TYR E 1 244 ? 22.352  -18.728 33.569 1.00 17.43  ? 446 TYR E CA  1 
ATOM   13362 C C   . TYR E 1 244 ? 22.166  -18.818 32.062 1.00 17.79  ? 446 TYR E C   1 
ATOM   13363 O O   . TYR E 1 244 ? 21.317  -19.560 31.569 1.00 17.62  ? 446 TYR E O   1 
ATOM   13364 C CB  . TYR E 1 244 ? 23.700  -19.338 33.986 1.00 19.26  ? 446 TYR E CB  1 
ATOM   13365 C CG  . TYR E 1 244 ? 23.964  -20.741 33.479 1.00 19.64  ? 446 TYR E CG  1 
ATOM   13366 C CD1 . TYR E 1 244 ? 24.672  -20.953 32.305 1.00 18.64  ? 446 TYR E CD1 1 
ATOM   13367 C CD2 . TYR E 1 244 ? 23.506  -21.849 34.172 1.00 20.62  ? 446 TYR E CD2 1 
ATOM   13368 C CE1 . TYR E 1 244 ? 24.918  -22.223 31.840 1.00 20.43  ? 446 TYR E CE1 1 
ATOM   13369 C CE2 . TYR E 1 244 ? 23.748  -23.124 33.710 1.00 21.46  ? 446 TYR E CE2 1 
ATOM   13370 C CZ  . TYR E 1 244 ? 24.452  -23.304 32.544 1.00 21.77  ? 446 TYR E CZ  1 
ATOM   13371 O OH  . TYR E 1 244 ? 24.694  -24.577 32.087 1.00 22.37  ? 446 TYR E OH  1 
ATOM   13372 N N   . LEU E 1 245 ? 22.969  -18.053 31.327 1.00 16.24  ? 447 LEU E N   1 
ATOM   13373 C CA  . LEU E 1 245 ? 22.853  -17.999 29.870 1.00 17.91  ? 447 LEU E CA  1 
ATOM   13374 C C   . LEU E 1 245 ? 23.802  -19.034 29.279 1.00 19.79  ? 447 LEU E C   1 
ATOM   13375 O O   . LEU E 1 245 ? 25.023  -18.896 29.332 1.00 20.50  ? 447 LEU E O   1 
ATOM   13376 C CB  . LEU E 1 245 ? 23.159  -16.593 29.370 1.00 15.89  ? 447 LEU E CB  1 
ATOM   13377 C CG  . LEU E 1 245 ? 23.136  -16.297 27.874 1.00 16.19  ? 447 LEU E CG  1 
ATOM   13378 C CD1 . LEU E 1 245 ? 21.759  -16.529 27.314 1.00 15.14  ? 447 LEU E CD1 1 
ATOM   13379 C CD2 . LEU E 1 245 ? 23.564  -14.868 27.638 1.00 16.82  ? 447 LEU E CD2 1 
ATOM   13380 N N   . SER E 1 246 ? 23.224  -20.101 28.721 1.00 20.72  ? 448 SER E N   1 
ATOM   13381 C CA  . SER E 1 246 ? 24.036  -21.209 28.226 1.00 22.37  ? 448 SER E CA  1 
ATOM   13382 C C   . SER E 1 246 ? 24.541  -20.968 26.806 1.00 24.00  ? 448 SER E C   1 
ATOM   13383 O O   . SER E 1 246 ? 25.711  -21.236 26.511 1.00 25.29  ? 448 SER E O   1 
ATOM   13384 C CB  . SER E 1 246 ? 23.245  -22.512 28.302 1.00 22.77  ? 448 SER E CB  1 
ATOM   13385 O OG  . SER E 1 246 ? 22.111  -22.473 27.461 1.00 24.36  ? 448 SER E OG  1 
ATOM   13386 N N   . LYS E 1 247 ? 23.685  -20.474 25.912 1.00 22.73  ? 449 LYS E N   1 
ATOM   13387 C CA  . LYS E 1 247 ? 24.017  -20.390 24.495 1.00 24.36  ? 449 LYS E CA  1 
ATOM   13388 C C   . LYS E 1 247 ? 23.531  -19.081 23.899 1.00 25.41  ? 449 LYS E C   1 
ATOM   13389 O O   . LYS E 1 247 ? 22.373  -18.701 24.081 1.00 26.31  ? 449 LYS E O   1 
ATOM   13390 C CB  . LYS E 1 247 ? 23.398  -21.542 23.702 1.00 26.79  ? 449 LYS E CB  1 
ATOM   13391 C CG  . LYS E 1 247 ? 24.016  -22.892 23.954 1.00 29.16  ? 449 LYS E CG  1 
ATOM   13392 C CD  . LYS E 1 247 ? 23.136  -23.976 23.375 1.00 31.96  ? 449 LYS E CD  1 
ATOM   13393 C CE  . LYS E 1 247 ? 22.964  -23.794 21.882 1.00 34.74  ? 449 LYS E CE  1 
ATOM   13394 N NZ  . LYS E 1 247 ? 22.068  -24.831 21.307 1.00 37.50  ? 449 LYS E NZ  1 
ATOM   13395 N N   . THR E 1 248 ? 24.421  -18.397 23.181 1.00 25.92  ? 450 THR E N   1 
ATOM   13396 C CA  . THR E 1 248 ? 24.065  -17.180 22.467 1.00 27.01  ? 450 THR E CA  1 
ATOM   13397 C C   . THR E 1 248 ? 23.812  -17.382 20.977 1.00 28.26  ? 450 THR E C   1 
ATOM   13398 O O   . THR E 1 248 ? 23.409  -16.426 20.307 1.00 28.24  ? 450 THR E O   1 
ATOM   13399 C CB  . THR E 1 248 ? 25.149  -16.119 22.665 1.00 28.70  ? 450 THR E CB  1 
ATOM   13400 O OG1 . THR E 1 248 ? 26.397  -16.613 22.170 1.00 29.36  ? 450 THR E OG1 1 
ATOM   13401 C CG2 . THR E 1 248 ? 25.291  -15.791 24.138 1.00 27.88  ? 450 THR E CG2 1 
ATOM   13402 N N   . ILE E 1 249 ? 24.020  -18.584 20.437 1.00 27.80  ? 451 ILE E N   1 
ATOM   13403 C CA  . ILE E 1 249 ? 23.723  -18.877 19.036 1.00 29.59  ? 451 ILE E CA  1 
ATOM   13404 C C   . ILE E 1 249 ? 23.200  -20.301 18.918 1.00 31.25  ? 451 ILE E C   1 
ATOM   13405 O O   . ILE E 1 249 ? 23.524  -21.164 19.739 1.00 31.78  ? 451 ILE E O   1 
ATOM   13406 C CB  . ILE E 1 249 ? 24.947  -18.694 18.111 1.00 28.13  ? 451 ILE E CB  1 
ATOM   13407 C CG1 . ILE E 1 249 ? 26.126  -19.538 18.589 1.00 28.13  ? 451 ILE E CG1 1 
ATOM   13408 C CG2 . ILE E 1 249 ? 25.309  -17.233 17.946 1.00 28.13  ? 451 ILE E CG2 1 
ATOM   13409 C CD1 . ILE E 1 249 ? 27.274  -19.557 17.617 1.00 28.13  ? 451 ILE E CD1 1 
ATOM   13410 N N   . ASN E 1 250 ? 22.395  -20.547 17.880 1.00 31.90  ? 452 ASN E N   1 
ATOM   13411 C CA  . ASN E 1 250 ? 21.871  -21.890 17.653 1.00 34.27  ? 452 ASN E CA  1 
ATOM   13412 C C   . ASN E 1 250 ? 22.951  -22.826 17.132 1.00 35.75  ? 452 ASN E C   1 
ATOM   13413 O O   . ASN E 1 250 ? 23.005  -23.998 17.522 1.00 35.90  ? 452 ASN E O   1 
ATOM   13414 C CB  . ASN E 1 250 ? 20.695  -21.844 16.679 1.00 31.87  ? 452 ASN E CB  1 
ATOM   13415 C CG  . ASN E 1 250 ? 19.500  -21.115 17.245 1.00 34.07  ? 452 ASN E CG  1 
ATOM   13416 O OD1 . ASN E 1 250 ? 18.922  -20.247 16.595 1.00 35.55  ? 452 ASN E OD1 1 
ATOM   13417 N ND2 . ASN E 1 250 ? 19.118  -21.468 18.464 1.00 35.39  ? 452 ASN E ND2 1 
ATOM   13418 N N   . GLY E 1 251 ? 23.805  -22.339 16.257 1.00 36.21  ? 453 GLY E N   1 
ATOM   13419 C CA  . GLY E 1 251 ? 24.862  -23.151 15.689 1.00 38.56  ? 453 GLY E CA  1 
ATOM   13420 C C   . GLY E 1 251 ? 25.711  -22.327 14.759 1.00 40.57  ? 453 GLY E C   1 
ATOM   13421 O O   . GLY E 1 251 ? 25.700  -21.096 14.808 1.00 41.56  ? 453 GLY E O   1 
ATOM   13422 N N   . SER E 1 252 ? 26.456  -23.013 13.900 1.00 43.54  ? 454 SER E N   1 
ATOM   13423 C CA  . SER E 1 252 ? 27.339  -22.372 12.937 1.00 44.04  ? 454 SER E CA  1 
ATOM   13424 C C   . SER E 1 252 ? 26.529  -21.941 11.724 1.00 43.29  ? 454 SER E C   1 
ATOM   13425 O O   . SER E 1 252 ? 25.718  -22.715 11.206 1.00 42.77  ? 454 SER E O   1 
ATOM   13426 C CB  . SER E 1 252 ? 28.468  -23.315 12.519 1.00 41.79  ? 454 SER E CB  1 
ATOM   13427 O OG  . SER E 1 252 ? 29.315  -22.704 11.562 1.00 43.79  ? 454 SER E OG  1 
ATOM   13428 N N   . GLY E 1 253 ? 26.748  -20.717 11.280 1.00 40.92  ? 455 GLY E N   1 
ATOM   13429 C CA  . GLY E 1 253 ? 26.015  -20.171 10.156 1.00 40.33  ? 455 GLY E CA  1 
ATOM   13430 C C   . GLY E 1 253 ? 25.883  -18.670 10.300 1.00 40.17  ? 455 GLY E C   1 
ATOM   13431 O O   . GLY E 1 253 ? 26.580  -18.031 11.081 1.00 39.94  ? 455 GLY E O   1 
ATOM   13432 N N   . GLN E 1 254 ? 24.960  -18.119 9.519  1.00 39.52  ? 456 GLN E N   1 
ATOM   13433 C CA  . GLN E 1 254 ? 24.688  -16.692 9.579  1.00 39.95  ? 456 GLN E CA  1 
ATOM   13434 C C   . GLN E 1 254 ? 23.346  -16.432 10.253 1.00 38.24  ? 456 GLN E C   1 
ATOM   13435 O O   . GLN E 1 254 ? 22.385  -17.187 10.086 1.00 38.39  ? 456 GLN E O   1 
ATOM   13436 C CB  . GLN E 1 254 ? 24.691  -16.092 8.174  1.00 39.25  ? 456 GLN E CB  1 
ATOM   13437 C CG  . GLN E 1 254 ? 26.024  -16.182 7.446  1.00 45.01  ? 456 GLN E CG  1 
ATOM   13438 C CD  . GLN E 1 254 ? 27.111  -15.352 8.098  1.00 48.37  ? 456 GLN E CD  1 
ATOM   13439 O OE1 . GLN E 1 254 ? 27.973  -15.877 8.802  1.00 49.28  ? 456 GLN E OE1 1 
ATOM   13440 N NE2 . GLN E 1 254 ? 27.076  -14.048 7.863  1.00 49.52  ? 456 GLN E NE2 1 
ATOM   13441 N N   . ASN E 1 255 ? 23.278  -15.325 10.989 1.00 37.53  ? 457 ASN E N   1 
ATOM   13442 C CA  . ASN E 1 255 ? 22.079  -14.913 11.727 1.00 35.79  ? 457 ASN E CA  1 
ATOM   13443 C C   . ASN E 1 255 ? 21.542  -16.026 12.611 1.00 33.85  ? 457 ASN E C   1 
ATOM   13444 O O   . ASN E 1 255 ? 20.368  -16.374 12.547 1.00 32.94  ? 457 ASN E O   1 
ATOM   13445 C CB  . ASN E 1 255 ? 20.977  -14.394 10.798 1.00 35.83  ? 457 ASN E CB  1 
ATOM   13446 C CG  . ASN E 1 255 ? 21.435  -13.242 9.938  1.00 37.11  ? 457 ASN E CG  1 
ATOM   13447 O OD1 . ASN E 1 255 ? 22.501  -12.681 10.154 1.00 37.91  ? 457 ASN E OD1 1 
ATOM   13448 N ND2 . ASN E 1 255 ? 20.625  -12.880 8.957  1.00 37.85  ? 457 ASN E ND2 1 
ATOM   13449 N N   . GLN E 1 256 ? 22.420  -16.584 13.433 1.00 33.78  ? 458 GLN E N   1 
ATOM   13450 C CA  . GLN E 1 256 ? 22.068  -17.661 14.345 1.00 32.02  ? 458 GLN E CA  1 
ATOM   13451 C C   . GLN E 1 256 ? 21.926  -17.202 15.791 1.00 30.19  ? 458 GLN E C   1 
ATOM   13452 O O   . GLN E 1 256 ? 21.840  -18.027 16.689 1.00 30.11  ? 458 GLN E O   1 
ATOM   13453 C CB  . GLN E 1 256 ? 23.093  -18.789 14.251 1.00 35.22  ? 458 GLN E CB  1 
ATOM   13454 C CG  . GLN E 1 256 ? 23.178  -19.422 12.875 1.00 37.82  ? 458 GLN E CG  1 
ATOM   13455 C CD  . GLN E 1 256 ? 21.871  -20.051 12.446 1.00 40.21  ? 458 GLN E CD  1 
ATOM   13456 O OE1 . GLN E 1 256 ? 21.350  -20.940 13.114 1.00 41.40  ? 458 GLN E OE1 1 
ATOM   13457 N NE2 . GLN E 1 256 ? 21.336  -19.597 11.322 1.00 41.54  ? 458 GLN E NE2 1 
ATOM   13458 N N   . GLN E 1 257 ? 21.904  -15.896 16.026 1.00 29.69  ? 459 GLN E N   1 
ATOM   13459 C CA  . GLN E 1 257 ? 21.805  -15.397 17.391 1.00 27.78  ? 459 GLN E CA  1 
ATOM   13460 C C   . GLN E 1 257 ? 20.521  -15.831 18.073 1.00 26.98  ? 459 GLN E C   1 
ATOM   13461 O O   . GLN E 1 257 ? 19.444  -15.774 17.495 1.00 27.25  ? 459 GLN E O   1 
ATOM   13462 C CB  . GLN E 1 257 ? 21.894  -13.871 17.431 1.00 28.45  ? 459 GLN E CB  1 
ATOM   13463 C CG  . GLN E 1 257 ? 23.033  -13.265 16.640 1.00 29.30  ? 459 GLN E CG  1 
ATOM   13464 C CD  . GLN E 1 257 ? 22.579  -12.720 15.310 1.00 28.67  ? 459 GLN E CD  1 
ATOM   13465 O OE1 . GLN E 1 257 ? 21.543  -13.114 14.790 1.00 28.70  ? 459 GLN E OE1 1 
ATOM   13466 N NE2 . GLN E 1 257 ? 23.349  -11.799 14.756 1.00 27.62  ? 459 GLN E NE2 1 
ATOM   13467 N N   . THR E 1 258 ? 20.654  -16.256 19.321 1.00 24.92  ? 460 THR E N   1 
ATOM   13468 C CA  . THR E 1 258 ? 19.533  -16.704 20.123 1.00 24.82  ? 460 THR E CA  1 
ATOM   13469 C C   . THR E 1 258 ? 19.900  -16.601 21.586 1.00 22.96  ? 460 THR E C   1 
ATOM   13470 O O   . THR E 1 258 ? 21.065  -16.472 21.922 1.00 23.31  ? 460 THR E O   1 
ATOM   13471 C CB  . THR E 1 258 ? 19.208  -18.171 19.836 1.00 25.72  ? 460 THR E CB  1 
ATOM   13472 O OG1 . THR E 1 258 ? 17.956  -18.507 20.438 1.00 25.35  ? 460 THR E OG1 1 
ATOM   13473 C CG2 . THR E 1 258 ? 20.286  -19.062 20.404 1.00 27.85  ? 460 THR E CG2 1 
ATOM   13474 N N   . LEU E 1 259 ? 18.907  -16.627 22.460 1.00 22.26  ? 461 LEU E N   1 
ATOM   13475 C CA  . LEU E 1 259 ? 19.169  -16.603 23.887 1.00 19.46  ? 461 LEU E CA  1 
ATOM   13476 C C   . LEU E 1 259 ? 18.619  -17.886 24.477 1.00 19.60  ? 461 LEU E C   1 
ATOM   13477 O O   . LEU E 1 259 ? 17.441  -18.175 24.341 1.00 20.89  ? 461 LEU E O   1 
ATOM   13478 C CB  . LEU E 1 259 ? 18.495  -15.401 24.540 1.00 20.37  ? 461 LEU E CB  1 
ATOM   13479 C CG  . LEU E 1 259 ? 19.362  -14.202 24.918 1.00 18.23  ? 461 LEU E CG  1 
ATOM   13480 C CD1 . LEU E 1 259 ? 20.624  -14.126 24.081 1.00 16.51  ? 461 LEU E CD1 1 
ATOM   13481 C CD2 . LEU E 1 259 ? 18.558  -12.919 24.824 1.00 16.43  ? 461 LEU E CD2 1 
ATOM   13482 N N   . LYS E 1 260 ? 19.476  -18.651 25.136 1.00 20.24  ? 462 LYS E N   1 
ATOM   13483 C CA  . LYS E 1 260 ? 19.076  -19.898 25.764 1.00 19.67  ? 462 LYS E CA  1 
ATOM   13484 C C   . LYS E 1 260 ? 19.530  -19.882 27.207 1.00 18.72  ? 462 LYS E C   1 
ATOM   13485 O O   . LYS E 1 260 ? 20.635  -19.455 27.501 1.00 18.24  ? 462 LYS E O   1 
ATOM   13486 C CB  . LYS E 1 260 ? 19.691  -21.088 25.044 1.00 21.89  ? 462 LYS E CB  1 
ATOM   13487 C CG  . LYS E 1 260 ? 19.260  -21.235 23.602 1.00 23.66  ? 462 LYS E CG  1 
ATOM   13488 C CD  . LYS E 1 260 ? 17.764  -21.433 23.503 1.00 24.46  ? 462 LYS E CD  1 
ATOM   13489 C CE  . LYS E 1 260 ? 17.343  -21.691 22.071 1.00 26.62  ? 462 LYS E CE  1 
ATOM   13490 N NZ  . LYS E 1 260 ? 15.864  -21.735 21.957 1.00 28.29  ? 462 LYS E NZ  1 
ATOM   13491 N N   . PHE E 1 261 ? 18.684  -20.358 28.107 1.00 21.10  ? 463 PHE E N   1 
ATOM   13492 C CA  . PHE E 1 261 ? 19.021  -20.370 29.518 1.00 19.73  ? 463 PHE E CA  1 
ATOM   13493 C C   . PHE E 1 261 ? 18.954  -21.779 30.058 1.00 19.49  ? 463 PHE E C   1 
ATOM   13494 O O   . PHE E 1 261 ? 18.213  -22.597 29.555 1.00 19.83  ? 463 PHE E O   1 
ATOM   13495 C CB  . PHE E 1 261 ? 18.078  -19.464 30.298 1.00 17.78  ? 463 PHE E CB  1 
ATOM   13496 C CG  . PHE E 1 261 ? 18.166  -18.022 29.907 1.00 16.26  ? 463 PHE E CG  1 
ATOM   13497 C CD1 . PHE E 1 261 ? 18.920  -17.138 30.648 1.00 15.34  ? 463 PHE E CD1 1 
ATOM   13498 C CD2 . PHE E 1 261 ? 17.496  -17.554 28.797 1.00 16.03  ? 463 PHE E CD2 1 
ATOM   13499 C CE1 . PHE E 1 261 ? 19.005  -15.812 30.290 1.00 14.24  ? 463 PHE E CE1 1 
ATOM   13500 C CE2 . PHE E 1 261 ? 17.574  -16.228 28.435 1.00 15.13  ? 463 PHE E CE2 1 
ATOM   13501 C CZ  . PHE E 1 261 ? 18.331  -15.358 29.181 1.00 14.27  ? 463 PHE E CZ  1 
ATOM   13502 N N   . SER E 1 262 ? 19.764  -22.072 31.062 1.00 20.69  ? 464 SER E N   1 
ATOM   13503 C CA  . SER E 1 262 ? 19.780  -23.397 31.653 1.00 21.19  ? 464 SER E CA  1 
ATOM   13504 C C   . SER E 1 262 ? 19.915  -23.307 33.152 1.00 21.33  ? 464 SER E C   1 
ATOM   13505 O O   . SER E 1 262 ? 20.516  -22.383 33.673 1.00 21.24  ? 464 SER E O   1 
ATOM   13506 C CB  . SER E 1 262 ? 20.949  -24.216 31.112 1.00 22.02  ? 464 SER E CB  1 
ATOM   13507 O OG  . SER E 1 262 ? 20.927  -24.296 29.703 1.00 22.27  ? 464 SER E OG  1 
ATOM   13508 N N   . VAL E 1 263 ? 19.341  -24.271 33.851 1.00 22.15  ? 465 VAL E N   1 
ATOM   13509 C CA  . VAL E 1 263 ? 19.451  -24.306 35.301 1.00 23.39  ? 465 VAL E CA  1 
ATOM   13510 C C   . VAL E 1 263 ? 20.908  -24.461 35.698 1.00 24.07  ? 465 VAL E C   1 
ATOM   13511 O O   . VAL E 1 263 ? 21.636  -25.306 35.161 1.00 24.36  ? 465 VAL E O   1 
ATOM   13512 C CB  . VAL E 1 263 ? 18.603  -25.451 35.878 1.00 26.51  ? 465 VAL E CB  1 
ATOM   13513 C CG1 . VAL E 1 263 ? 18.828  -25.581 37.366 1.00 26.76  ? 465 VAL E CG1 1 
ATOM   13514 C CG2 . VAL E 1 263 ? 17.145  -25.219 35.598 1.00 27.12  ? 465 VAL E CG2 1 
ATOM   13515 N N   . ALA E 1 264 ? 21.345  -23.639 36.644 1.00 25.73  ? 466 ALA E N   1 
ATOM   13516 C CA  . ALA E 1 264 ? 22.656  -23.842 37.235 1.00 26.95  ? 466 ALA E CA  1 
ATOM   13517 C C   . ALA E 1 264 ? 22.582  -24.976 38.246 1.00 28.42  ? 466 ALA E C   1 
ATOM   13518 O O   . ALA E 1 264 ? 21.813  -24.923 39.209 1.00 28.88  ? 466 ALA E O   1 
ATOM   13519 C CB  . ALA E 1 264 ? 23.149  -22.561 37.903 1.00 24.74  ? 466 ALA E CB  1 
ATOM   13520 N N   . GLY E 1 265 ? 23.390  -26.006 38.026 1.00 32.05  ? 467 GLY E N   1 
ATOM   13521 C CA  . GLY E 1 265 ? 23.274  -27.223 38.786 1.00 32.89  ? 467 GLY E CA  1 
ATOM   13522 C C   . GLY E 1 265 ? 24.582  -27.971 38.922 1.00 33.15  ? 467 GLY E C   1 
ATOM   13523 O O   . GLY E 1 265 ? 25.640  -27.513 38.487 1.00 32.90  ? 467 GLY E O   1 
ATOM   13524 N N   . PRO E 1 266 ? 24.520  -29.147 39.549 1.00 38.72  ? 468 PRO E N   1 
ATOM   13525 C CA  . PRO E 1 266 ? 25.751  -29.891 39.866 1.00 39.11  ? 468 PRO E CA  1 
ATOM   13526 C C   . PRO E 1 266 ? 26.628  -30.200 38.665 1.00 39.71  ? 468 PRO E C   1 
ATOM   13527 O O   . PRO E 1 266 ? 27.849  -30.323 38.818 1.00 39.58  ? 468 PRO E O   1 
ATOM   13528 C CB  . PRO E 1 266 ? 25.208  -31.173 40.506 1.00 36.73  ? 468 PRO E CB  1 
ATOM   13529 C CG  . PRO E 1 266 ? 23.876  -30.778 41.051 1.00 36.65  ? 468 PRO E CG  1 
ATOM   13530 C CD  . PRO E 1 266 ? 23.320  -29.825 40.056 1.00 37.02  ? 468 PRO E CD  1 
ATOM   13531 N N   . SER E 1 267 ? 26.045  -30.344 37.475 1.00 38.72  ? 469 SER E N   1 
ATOM   13532 C CA  . SER E 1 267 ? 26.854  -30.645 36.300 1.00 39.50  ? 469 SER E CA  1 
ATOM   13533 C C   . SER E 1 267 ? 27.812  -29.505 35.985 1.00 39.46  ? 469 SER E C   1 
ATOM   13534 O O   . SER E 1 267 ? 28.998  -29.737 35.725 1.00 39.66  ? 469 SER E O   1 
ATOM   13535 C CB  . SER E 1 267 ? 25.955  -30.936 35.100 1.00 38.64  ? 469 SER E CB  1 
ATOM   13536 O OG  . SER E 1 267 ? 25.176  -29.803 34.761 1.00 43.18  ? 469 SER E OG  1 
ATOM   13537 N N   . ASN E 1 268 ? 27.320  -28.269 35.994 1.00 39.37  ? 470 ASN E N   1 
ATOM   13538 C CA  . ASN E 1 268 ? 28.150  -27.090 35.757 1.00 38.09  ? 470 ASN E CA  1 
ATOM   13539 C C   . ASN E 1 268 ? 28.166  -26.271 37.043 1.00 36.63  ? 470 ASN E C   1 
ATOM   13540 O O   . ASN E 1 268 ? 27.207  -25.564 37.356 1.00 35.50  ? 470 ASN E O   1 
ATOM   13541 C CB  . ASN E 1 268 ? 27.589  -26.298 34.570 1.00 38.55  ? 470 ASN E CB  1 
ATOM   13542 C CG  . ASN E 1 268 ? 28.522  -25.210 34.093 1.00 41.19  ? 470 ASN E CG  1 
ATOM   13543 O OD1 . ASN E 1 268 ? 29.410  -24.769 34.818 1.00 42.03  ? 470 ASN E OD1 1 
ATOM   13544 N ND2 . ASN E 1 268 ? 28.326  -24.773 32.858 1.00 42.02  ? 470 ASN E ND2 1 
ATOM   13545 N N   . MET E 1 269 ? 29.283  -26.332 37.771 1.00 32.99  ? 471 MET E N   1 
ATOM   13546 C CA  . MET E 1 269 ? 29.354  -25.640 39.054 1.00 32.77  ? 471 MET E CA  1 
ATOM   13547 C C   . MET E 1 269 ? 29.968  -24.257 38.916 1.00 31.57  ? 471 MET E C   1 
ATOM   13548 O O   . MET E 1 269 ? 29.942  -23.463 39.862 1.00 32.24  ? 471 MET E O   1 
ATOM   13549 C CB  . MET E 1 269 ? 30.143  -26.468 40.065 1.00 34.21  ? 471 MET E CB  1 
ATOM   13550 C CG  . MET E 1 269 ? 29.425  -27.706 40.543 1.00 36.96  ? 471 MET E CG  1 
ATOM   13551 S SD  . MET E 1 269 ? 30.370  -28.604 41.780 1.00 38.86  ? 471 MET E SD  1 
ATOM   13552 C CE  . MET E 1 269 ? 29.211  -29.899 42.192 1.00 39.01  ? 471 MET E CE  1 
ATOM   13553 N N   . ALA E 1 270 ? 30.525  -23.946 37.749 1.00 33.91  ? 472 ALA E N   1 
ATOM   13554 C CA  . ALA E 1 270 ? 31.216  -22.672 37.592 1.00 32.20  ? 472 ALA E CA  1 
ATOM   13555 C C   . ALA E 1 270 ? 30.230  -21.523 37.436 1.00 31.26  ? 472 ALA E C   1 
ATOM   13556 O O   . ALA E 1 270 ? 30.540  -20.376 37.775 1.00 31.10  ? 472 ALA E O   1 
ATOM   13557 C CB  . ALA E 1 270 ? 32.161  -22.738 36.393 1.00 35.95  ? 472 ALA E CB  1 
ATOM   13558 N N   . VAL E 1 271 ? 29.032  -21.813 36.930 1.00 30.44  ? 473 VAL E N   1 
ATOM   13559 C CA  . VAL E 1 271 ? 28.127  -20.749 36.513 1.00 29.29  ? 473 VAL E CA  1 
ATOM   13560 C C   . VAL E 1 271 ? 27.084  -20.454 37.584 1.00 27.78  ? 473 VAL E C   1 
ATOM   13561 O O   . VAL E 1 271 ? 26.213  -19.597 37.396 1.00 27.28  ? 473 VAL E O   1 
ATOM   13562 C CB  . VAL E 1 271 ? 27.478  -21.122 35.174 1.00 26.18  ? 473 VAL E CB  1 
ATOM   13563 C CG1 . VAL E 1 271 ? 28.533  -21.195 34.096 1.00 30.53  ? 473 VAL E CG1 1 
ATOM   13564 C CG2 . VAL E 1 271 ? 26.780  -22.450 35.304 1.00 26.78  ? 473 VAL E CG2 1 
ATOM   13565 N N   . GLN E 1 272 ? 27.143  -21.152 38.715 1.00 28.95  ? 474 GLN E N   1 
ATOM   13566 C CA  . GLN E 1 272 ? 26.148  -20.950 39.760 1.00 27.52  ? 474 GLN E CA  1 
ATOM   13567 C C   . GLN E 1 272 ? 26.328  -19.600 40.437 1.00 27.06  ? 474 GLN E C   1 
ATOM   13568 O O   . GLN E 1 272 ? 27.442  -19.083 40.535 1.00 27.56  ? 474 GLN E O   1 
ATOM   13569 C CB  . GLN E 1 272 ? 26.234  -22.057 40.808 1.00 26.17  ? 474 GLN E CB  1 
ATOM   13570 C CG  . GLN E 1 272 ? 25.893  -23.441 40.322 1.00 29.21  ? 474 GLN E CG  1 
ATOM   13571 C CD  . GLN E 1 272 ? 25.880  -24.427 41.460 1.00 30.84  ? 474 GLN E CD  1 
ATOM   13572 O OE1 . GLN E 1 272 ? 26.424  -24.153 42.524 1.00 32.08  ? 474 GLN E OE1 1 
ATOM   13573 N NE2 . GLN E 1 272 ? 25.270  -25.583 41.245 1.00 32.52  ? 474 GLN E NE2 1 
ATOM   13574 N N   . GLY E 1 273 ? 25.223  -19.039 40.918 1.00 23.27  ? 475 GLY E N   1 
ATOM   13575 C CA  . GLY E 1 273 ? 25.310  -17.800 41.670 1.00 22.13  ? 475 GLY E CA  1 
ATOM   13576 C C   . GLY E 1 273 ? 25.922  -18.035 43.039 1.00 22.89  ? 475 GLY E C   1 
ATOM   13577 O O   . GLY E 1 273 ? 25.710  -19.076 43.665 1.00 23.34  ? 475 GLY E O   1 
ATOM   13578 N N   . ARG E 1 274 ? 26.695  -17.057 43.503 1.00 23.42  ? 476 ARG E N   1 
ATOM   13579 C CA  . ARG E 1 274 ? 27.380  -17.149 44.781 1.00 23.17  ? 476 ARG E CA  1 
ATOM   13580 C C   . ARG E 1 274 ? 27.238  -15.842 45.547 1.00 22.91  ? 476 ARG E C   1 
ATOM   13581 O O   . ARG E 1 274 ? 27.053  -14.774 44.960 1.00 24.00  ? 476 ARG E O   1 
ATOM   13582 C CB  . ARG E 1 274 ? 28.857  -17.499 44.593 1.00 21.16  ? 476 ARG E CB  1 
ATOM   13583 C CG  . ARG E 1 274 ? 29.079  -18.898 44.059 1.00 22.71  ? 476 ARG E CG  1 
ATOM   13584 C CD  . ARG E 1 274 ? 30.543  -19.198 43.838 1.00 24.06  ? 476 ARG E CD  1 
ATOM   13585 N NE  . ARG E 1 274 ? 30.742  -20.552 43.338 1.00 28.29  ? 476 ARG E NE  1 
ATOM   13586 C CZ  . ARG E 1 274 ? 30.649  -20.895 42.060 1.00 29.16  ? 476 ARG E CZ  1 
ATOM   13587 N NH1 . ARG E 1 274 ? 30.364  -19.980 41.147 1.00 31.97  ? 476 ARG E NH1 1 
ATOM   13588 N NH2 . ARG E 1 274 ? 30.846  -22.150 41.693 1.00 31.26  ? 476 ARG E NH2 1 
ATOM   13589 N N   . ASN E 1 275 ? 27.312  -15.943 46.873 1.00 22.90  ? 477 ASN E N   1 
ATOM   13590 C CA  . ASN E 1 275 ? 27.139  -14.792 47.749 1.00 22.27  ? 477 ASN E CA  1 
ATOM   13591 C C   . ASN E 1 275 ? 28.440  -14.095 48.111 1.00 21.91  ? 477 ASN E C   1 
ATOM   13592 O O   . ASN E 1 275 ? 28.398  -12.999 48.678 1.00 20.93  ? 477 ASN E O   1 
ATOM   13593 C CB  . ASN E 1 275 ? 26.439  -15.224 49.038 1.00 22.42  ? 477 ASN E CB  1 
ATOM   13594 C CG  . ASN E 1 275 ? 24.980  -15.542 48.828 1.00 23.94  ? 477 ASN E CG  1 
ATOM   13595 O OD1 . ASN E 1 275 ? 24.337  -14.987 47.941 1.00 26.26  ? 477 ASN E OD1 1 
ATOM   13596 N ND2 . ASN E 1 275 ? 24.453  -16.456 49.626 1.00 24.28  ? 477 ASN E ND2 1 
ATOM   13597 N N   . TYR E 1 276 ? 29.587  -14.693 47.812 1.00 21.73  ? 478 TYR E N   1 
ATOM   13598 C CA  . TYR E 1 276 ? 30.861  -14.146 48.249 1.00 22.79  ? 478 TYR E CA  1 
ATOM   13599 C C   . TYR E 1 276 ? 31.920  -14.441 47.204 1.00 23.87  ? 478 TYR E C   1 
ATOM   13600 O O   . TYR E 1 276 ? 31.827  -15.431 46.474 1.00 26.00  ? 478 TYR E O   1 
ATOM   13601 C CB  . TYR E 1 276 ? 31.282  -14.720 49.609 1.00 22.99  ? 478 TYR E CB  1 
ATOM   13602 C CG  . TYR E 1 276 ? 30.313  -14.378 50.713 1.00 25.20  ? 478 TYR E CG  1 
ATOM   13603 C CD1 . TYR E 1 276 ? 30.419  -13.188 51.414 1.00 25.70  ? 478 TYR E CD1 1 
ATOM   13604 C CD2 . TYR E 1 276 ? 29.279  -15.238 51.042 1.00 24.39  ? 478 TYR E CD2 1 
ATOM   13605 C CE1 . TYR E 1 276 ? 29.527  -12.870 52.414 1.00 25.94  ? 478 TYR E CE1 1 
ATOM   13606 C CE2 . TYR E 1 276 ? 28.381  -14.927 52.033 1.00 26.24  ? 478 TYR E CE2 1 
ATOM   13607 C CZ  . TYR E 1 276 ? 28.510  -13.745 52.719 1.00 27.06  ? 478 TYR E CZ  1 
ATOM   13608 O OH  . TYR E 1 276 ? 27.614  -13.438 53.714 1.00 28.61  ? 478 TYR E OH  1 
ATOM   13609 N N   . ILE E 1 277 ? 32.919  -13.574 47.138 1.00 26.27  ? 479 ILE E N   1 
ATOM   13610 C CA  . ILE E 1 277 ? 33.962  -13.647 46.120 1.00 25.66  ? 479 ILE E CA  1 
ATOM   13611 C C   . ILE E 1 277 ? 35.298  -13.464 46.826 1.00 26.82  ? 479 ILE E C   1 
ATOM   13612 O O   . ILE E 1 277 ? 35.358  -12.898 47.931 1.00 27.19  ? 479 ILE E O   1 
ATOM   13613 C CB  . ILE E 1 277 ? 33.737  -12.606 44.999 1.00 26.71  ? 479 ILE E CB  1 
ATOM   13614 C CG1 . ILE E 1 277 ? 33.668  -11.200 45.584 1.00 25.08  ? 479 ILE E CG1 1 
ATOM   13615 C CG2 . ILE E 1 277 ? 32.467  -12.916 44.239 1.00 25.53  ? 479 ILE E CG2 1 
ATOM   13616 C CD1 . ILE E 1 277 ? 33.586  -10.117 44.546 1.00 23.59  ? 479 ILE E CD1 1 
ATOM   13617 N N   . PRO E 1 278 ? 36.389  -13.953 46.236 1.00 31.29  ? 480 PRO E N   1 
ATOM   13618 C CA  . PRO E 1 278 ? 37.681  -13.915 46.928 1.00 31.73  ? 480 PRO E CA  1 
ATOM   13619 C C   . PRO E 1 278 ? 38.195  -12.497 47.122 1.00 32.41  ? 480 PRO E C   1 
ATOM   13620 O O   . PRO E 1 278 ? 37.745  -11.541 46.487 1.00 31.89  ? 480 PRO E O   1 
ATOM   13621 C CB  . PRO E 1 278 ? 38.597  -14.723 46.006 1.00 31.84  ? 480 PRO E CB  1 
ATOM   13622 C CG  . PRO E 1 278 ? 37.965  -14.621 44.676 1.00 32.29  ? 480 PRO E CG  1 
ATOM   13623 C CD  . PRO E 1 278 ? 36.497  -14.644 44.943 1.00 31.07  ? 480 PRO E CD  1 
ATOM   13624 N N   . GLY E 1 279 ? 39.168  -12.380 48.022 1.00 31.32  ? 481 GLY E N   1 
ATOM   13625 C CA  . GLY E 1 279 ? 39.692  -11.104 48.439 1.00 32.39  ? 481 GLY E CA  1 
ATOM   13626 C C   . GLY E 1 279 ? 40.520  -10.408 47.381 1.00 33.26  ? 481 GLY E C   1 
ATOM   13627 O O   . GLY E 1 279 ? 40.647  -10.875 46.246 1.00 33.81  ? 481 GLY E O   1 
ATOM   13628 N N   . PRO E 1 280 ? 41.101  -9.269  47.741 1.00 33.58  ? 482 PRO E N   1 
ATOM   13629 C CA  . PRO E 1 280 ? 41.814  -8.453  46.758 1.00 34.13  ? 482 PRO E CA  1 
ATOM   13630 C C   . PRO E 1 280 ? 43.111  -9.103  46.303 1.00 35.13  ? 482 PRO E C   1 
ATOM   13631 O O   . PRO E 1 280 ? 43.638  -10.024 46.929 1.00 35.23  ? 482 PRO E O   1 
ATOM   13632 C CB  . PRO E 1 280 ? 42.087  -7.153  47.518 1.00 31.17  ? 482 PRO E CB  1 
ATOM   13633 C CG  . PRO E 1 280 ? 42.129  -7.562  48.935 1.00 31.04  ? 482 PRO E CG  1 
ATOM   13634 C CD  . PRO E 1 280 ? 41.130  -8.666  49.083 1.00 30.73  ? 482 PRO E CD  1 
ATOM   13635 N N   . SER E 1 281 ? 43.620  -8.598  45.183 1.00 34.69  ? 483 SER E N   1 
ATOM   13636 C CA  . SER E 1 281 ? 44.828  -9.130  44.574 1.00 35.55  ? 483 SER E CA  1 
ATOM   13637 C C   . SER E 1 281 ? 45.677  -7.988  44.043 1.00 34.97  ? 483 SER E C   1 
ATOM   13638 O O   . SER E 1 281 ? 45.156  -6.982  43.559 1.00 35.41  ? 483 SER E O   1 
ATOM   13639 C CB  . SER E 1 281 ? 44.508  -10.093 43.429 1.00 32.37  ? 483 SER E CB  1 
ATOM   13640 O OG  . SER E 1 281 ? 43.882  -9.401  42.365 1.00 34.81  ? 483 SER E OG  1 
ATOM   13641 N N   . TYR E 1 282 ? 46.992  -8.140  44.170 1.00 43.57  ? 484 TYR E N   1 
ATOM   13642 C CA  . TYR E 1 282 ? 47.958  -7.251  43.532 1.00 41.60  ? 484 TYR E CA  1 
ATOM   13643 C C   . TYR E 1 282 ? 49.030  -8.161  42.945 1.00 41.02  ? 484 TYR E C   1 
ATOM   13644 O O   . TYR E 1 282 ? 49.797  -8.760  43.701 1.00 41.29  ? 484 TYR E O   1 
ATOM   13645 C CB  . TYR E 1 282 ? 48.533  -6.289  44.571 1.00 43.86  ? 484 TYR E CB  1 
ATOM   13646 C CG  . TYR E 1 282 ? 49.417  -5.174  44.074 1.00 42.80  ? 484 TYR E CG  1 
ATOM   13647 C CD1 . TYR E 1 282 ? 48.867  -4.001  43.580 1.00 42.66  ? 484 TYR E CD1 1 
ATOM   13648 C CD2 . TYR E 1 282 ? 50.797  -5.274  44.134 1.00 42.12  ? 484 TYR E CD2 1 
ATOM   13649 C CE1 . TYR E 1 282 ? 49.663  -2.967  43.149 1.00 41.76  ? 484 TYR E CE1 1 
ATOM   13650 C CE2 . TYR E 1 282 ? 51.602  -4.246  43.698 1.00 41.21  ? 484 TYR E CE2 1 
ATOM   13651 C CZ  . TYR E 1 282 ? 51.031  -3.095  43.204 1.00 41.71  ? 484 TYR E CZ  1 
ATOM   13652 O OH  . TYR E 1 282 ? 51.828  -2.064  42.767 1.00 41.40  ? 484 TYR E OH  1 
ATOM   13653 N N   . ARG E 1 283 ? 49.122  -8.253  41.618 1.00 42.04  ? 485 ARG E N   1 
ATOM   13654 C CA  . ARG E 1 283 ? 49.849  -9.383  41.050 1.00 41.53  ? 485 ARG E CA  1 
ATOM   13655 C C   . ARG E 1 283 ? 51.354  -9.242  41.246 1.00 41.61  ? 485 ARG E C   1 
ATOM   13656 O O   . ARG E 1 283 ? 51.933  -8.176  41.026 1.00 41.20  ? 485 ARG E O   1 
ATOM   13657 C CB  . ARG E 1 283 ? 49.562  -9.573  39.559 1.00 38.88  ? 485 ARG E CB  1 
ATOM   13658 C CG  . ARG E 1 283 ? 50.270  -10.843 39.080 1.00 40.48  ? 485 ARG E CG  1 
ATOM   13659 C CD  . ARG E 1 283 ? 50.316  -11.128 37.595 1.00 39.92  ? 485 ARG E CD  1 
ATOM   13660 N NE  . ARG E 1 283 ? 49.046  -11.491 36.989 1.00 40.59  ? 485 ARG E NE  1 
ATOM   13661 C CZ  . ARG E 1 283 ? 48.932  -11.873 35.722 1.00 40.02  ? 485 ARG E CZ  1 
ATOM   13662 N NH1 . ARG E 1 283 ? 50.012  -11.959 34.962 1.00 39.03  ? 485 ARG E NH1 1 
ATOM   13663 N NH2 . ARG E 1 283 ? 47.752  -12.190 35.219 1.00 42.23  ? 485 ARG E NH2 1 
ATOM   13664 N N   . GLN E 1 284 ? 51.997  -10.302 41.737 1.00 43.45  ? 486 GLN E N   1 
ATOM   13665 C CA  . GLN E 1 284 ? 53.437  -10.345 41.886 1.00 44.00  ? 486 GLN E CA  1 
ATOM   13666 C C   . GLN E 1 284 ? 53.987  -11.150 40.708 1.00 44.80  ? 486 GLN E C   1 
ATOM   13667 O O   . GLN E 1 284 ? 53.302  -12.013 40.175 1.00 44.42  ? 486 GLN E O   1 
ATOM   13668 C CB  . GLN E 1 284 ? 53.804  -11.046 43.187 1.00 42.02  ? 486 GLN E CB  1 
ATOM   13669 C CG  . GLN E 1 284 ? 53.599  -10.204 44.428 1.00 43.90  ? 486 GLN E CG  1 
ATOM   13670 C CD  . GLN E 1 284 ? 54.714  -9.209  44.633 1.00 45.76  ? 486 GLN E CD  1 
ATOM   13671 O OE1 . GLN E 1 284 ? 55.760  -9.299  43.997 1.00 46.96  ? 486 GLN E OE1 1 
ATOM   13672 N NE2 . GLN E 1 284 ? 54.500  -8.257  45.526 1.00 46.64  ? 486 GLN E NE2 1 
ATOM   13673 N N   . GLN E 1 285 ? 55.214  -10.862 40.290 1.00 48.57  ? 487 GLN E N   1 
ATOM   13674 C CA  . GLN E 1 285 ? 55.845  -11.602 39.197 1.00 48.63  ? 487 GLN E CA  1 
ATOM   13675 C C   . GLN E 1 285 ? 56.147  -13.024 39.677 1.00 49.06  ? 487 GLN E C   1 
ATOM   13676 O O   . GLN E 1 285 ? 56.435  -13.231 40.850 1.00 49.15  ? 487 GLN E O   1 
ATOM   13677 C CB  . GLN E 1 285 ? 57.117  -10.888 38.737 1.00 50.84  ? 487 GLN E CB  1 
ATOM   13678 C CG  . GLN E 1 285 ? 57.845  -11.545 37.578 1.00 50.75  ? 487 GLN E CG  1 
ATOM   13679 C CD  . GLN E 1 285 ? 56.973  -11.729 36.354 1.00 51.28  ? 487 GLN E CD  1 
ATOM   13680 O OE1 . GLN E 1 285 ? 57.157  -12.668 35.585 1.00 48.62  ? 487 GLN E OE1 1 
ATOM   13681 N NE2 . GLN E 1 285 ? 56.019  -10.834 36.168 1.00 51.45  ? 487 GLN E NE2 1 
ATOM   13682 N N   . ARG E 1 286 ? 56.095  -14.002 38.779 1.00 48.53  ? 488 ARG E N   1 
ATOM   13683 C CA  . ARG E 1 286 ? 56.328  -15.388 39.168 1.00 48.48  ? 488 ARG E CA  1 
ATOM   13684 C C   . ARG E 1 286 ? 57.718  -15.884 38.826 1.00 48.42  ? 488 ARG E C   1 
ATOM   13685 O O   . ARG E 1 286 ? 58.172  -15.767 37.698 1.00 50.09  ? 488 ARG E O   1 
ATOM   13686 C CB  . ARG E 1 286 ? 55.294  -16.303 38.524 1.00 48.25  ? 488 ARG E CB  1 
ATOM   13687 C CG  . ARG E 1 286 ? 55.322  -17.723 39.055 1.00 49.35  ? 488 ARG E CG  1 
ATOM   13688 C CD  . ARG E 1 286 ? 54.506  -18.654 38.180 1.00 51.67  ? 488 ARG E CD  1 
ATOM   13689 N NE  . ARG E 1 286 ? 55.012  -18.695 36.815 1.00 54.81  ? 488 ARG E NE  1 
ATOM   13690 C CZ  . ARG E 1 286 ? 54.651  -19.602 35.916 1.00 57.48  ? 488 ARG E CZ  1 
ATOM   13691 N NH1 . ARG E 1 286 ? 55.162  -19.566 34.694 1.00 55.34  ? 488 ARG E NH1 1 
ATOM   13692 N NH2 . ARG E 1 286 ? 53.784  -20.549 36.238 1.00 60.66  ? 488 ARG E NH2 1 
ATOM   13693 N N   . VAL E 1 287 ? 58.382  -16.460 39.818 1.00 53.26  ? 489 VAL E N   1 
ATOM   13694 C CA  . VAL E 1 287 ? 59.734  -16.965 39.650 1.00 52.85  ? 489 VAL E CA  1 
ATOM   13695 C C   . VAL E 1 287 ? 59.844  -18.466 39.896 1.00 53.37  ? 489 VAL E C   1 
ATOM   13696 O O   . VAL E 1 287 ? 59.331  -18.982 40.885 1.00 54.41  ? 489 VAL E O   1 
ATOM   13697 C CB  . VAL E 1 287 ? 60.712  -16.243 40.590 1.00 52.53  ? 489 VAL E CB  1 
ATOM   13698 C CG1 . VAL E 1 287 ? 62.140  -16.623 40.252 1.00 51.46  ? 489 VAL E CG1 1 
ATOM   13699 C CG2 . VAL E 1 287 ? 60.524  -14.741 40.488 1.00 53.37  ? 489 VAL E CG2 1 
ATOM   13700 N N   . SER E 1 288 ? 60.517  -19.158 38.986 1.00 57.54  ? 490 SER E N   1 
ATOM   13701 C CA  . SER E 1 288 ? 60.714  -20.593 39.106 1.00 57.99  ? 490 SER E CA  1 
ATOM   13702 C C   . SER E 1 288 ? 62.022  -20.919 39.809 1.00 58.89  ? 490 SER E C   1 
ATOM   13703 O O   . SER E 1 288 ? 63.036  -20.271 39.574 1.00 57.47  ? 490 SER E O   1 
ATOM   13704 C CB  . SER E 1 288 ? 60.721  -21.244 37.730 1.00 60.54  ? 490 SER E CB  1 
ATOM   13705 O OG  . SER E 1 288 ? 61.215  -22.566 37.819 1.00 60.61  ? 490 SER E OG  1 
ATOM   13706 N N   . THR E 1 289 ? 61.992  -21.929 40.670 1.00 57.58  ? 491 THR E N   1 
ATOM   13707 C CA  . THR E 1 289 ? 63.178  -22.360 41.396 1.00 60.11  ? 491 THR E CA  1 
ATOM   13708 C C   . THR E 1 289 ? 64.168  -23.105 40.512 1.00 61.94  ? 491 THR E C   1 
ATOM   13709 O O   . THR E 1 289 ? 65.328  -23.261 40.906 1.00 63.04  ? 491 THR E O   1 
ATOM   13710 C CB  . THR E 1 289 ? 62.787  -23.237 42.586 1.00 61.56  ? 491 THR E CB  1 
ATOM   13711 O OG1 . THR E 1 289 ? 62.041  -24.370 42.126 1.00 64.96  ? 491 THR E OG1 1 
ATOM   13712 C CG2 . THR E 1 289 ? 61.947  -22.443 43.572 1.00 60.45  ? 491 THR E CG2 1 
ATOM   13713 N N   . THR E 1 290 ? 63.746  -23.558 39.334 1.00 62.70  ? 492 THR E N   1 
ATOM   13714 C CA  . THR E 1 290 ? 64.657  -24.109 38.338 1.00 63.79  ? 492 THR E CA  1 
ATOM   13715 C C   . THR E 1 290 ? 65.122  -22.951 37.465 1.00 63.52  ? 492 THR E C   1 
ATOM   13716 O O   . THR E 1 290 ? 64.322  -22.349 36.742 1.00 63.64  ? 492 THR E O   1 
ATOM   13717 C CB  . THR E 1 290 ? 63.971  -25.193 37.511 1.00 60.87  ? 492 THR E CB  1 
ATOM   13718 O OG1 . THR E 1 290 ? 63.572  -26.268 38.369 1.00 63.23  ? 492 THR E OG1 1 
ATOM   13719 C CG2 . THR E 1 290 ? 64.912  -25.727 36.447 1.00 60.71  ? 492 THR E CG2 1 
ATOM   13720 N N   . VAL E 1 291 ? 66.417  -22.642 37.532 1.00 65.13  ? 493 VAL E N   1 
ATOM   13721 C CA  . VAL E 1 291 ? 66.904  -21.367 37.017 1.00 64.90  ? 493 VAL E CA  1 
ATOM   13722 C C   . VAL E 1 291 ? 66.771  -21.269 35.502 1.00 64.39  ? 493 VAL E C   1 
ATOM   13723 O O   . VAL E 1 291 ? 66.502  -20.186 34.975 1.00 64.26  ? 493 VAL E O   1 
ATOM   13724 C CB  . VAL E 1 291 ? 68.355  -21.135 37.470 1.00 62.72  ? 493 VAL E CB  1 
ATOM   13725 C CG1 . VAL E 1 291 ? 68.417  -21.016 38.982 1.00 64.38  ? 493 VAL E CG1 1 
ATOM   13726 C CG2 . VAL E 1 291 ? 69.256  -22.262 36.991 1.00 62.59  ? 493 VAL E CG2 1 
ATOM   13727 N N   . THR E 1 292 ? 66.943  -22.375 34.776 1.00 67.98  ? 494 THR E N   1 
ATOM   13728 C CA  . THR E 1 292 ? 66.893  -22.311 33.320 1.00 67.41  ? 494 THR E CA  1 
ATOM   13729 C C   . THR E 1 292 ? 65.514  -21.929 32.806 1.00 67.19  ? 494 THR E C   1 
ATOM   13730 O O   . THR E 1 292 ? 65.392  -21.480 31.661 1.00 67.30  ? 494 THR E O   1 
ATOM   13731 C CB  . THR E 1 292 ? 67.317  -23.647 32.717 1.00 70.29  ? 494 THR E CB  1 
ATOM   13732 O OG1 . THR E 1 292 ? 66.439  -24.679 33.183 1.00 70.55  ? 494 THR E OG1 1 
ATOM   13733 C CG2 . THR E 1 292 ? 68.740  -23.979 33.125 1.00 69.33  ? 494 THR E CG2 1 
ATOM   13734 N N   . GLN E 1 293 ? 64.493  -22.090 33.636 1.00 66.14  ? 495 GLN E N   1 
ATOM   13735 C CA  . GLN E 1 293 ? 63.131  -21.765 33.236 1.00 65.30  ? 495 GLN E CA  1 
ATOM   13736 C C   . GLN E 1 293 ? 62.881  -20.266 33.255 1.00 64.89  ? 495 GLN E C   1 
ATOM   13737 O O   . GLN E 1 293 ? 61.987  -19.773 32.576 1.00 65.31  ? 495 GLN E O   1 
ATOM   13738 C CB  . GLN E 1 293 ? 62.133  -22.503 34.126 1.00 60.82  ? 495 GLN E CB  1 
ATOM   13739 C CG  . GLN E 1 293 ? 62.402  -23.997 34.177 1.00 63.30  ? 495 GLN E CG  1 
ATOM   13740 C CD  . GLN E 1 293 ? 61.269  -24.793 34.786 1.00 65.17  ? 495 GLN E CD  1 
ATOM   13741 O OE1 . GLN E 1 293 ? 60.621  -24.351 35.728 1.00 66.95  ? 495 GLN E OE1 1 
ATOM   13742 N NE2 . GLN E 1 293 ? 61.034  -25.982 34.252 1.00 66.52  ? 495 GLN E NE2 1 
ATOM   13743 N N   . ASN E 1 294 ? 63.664  -19.551 34.051 1.00 65.39  ? 496 ASN E N   1 
ATOM   13744 C CA  . ASN E 1 294 ? 63.552  -18.101 34.154 1.00 64.71  ? 496 ASN E CA  1 
ATOM   13745 C C   . ASN E 1 294 ? 64.123  -17.390 32.933 1.00 65.25  ? 496 ASN E C   1 
ATOM   13746 O O   . ASN E 1 294 ? 64.983  -17.918 32.240 1.00 65.18  ? 496 ASN E O   1 
ATOM   13747 C CB  . ASN E 1 294 ? 64.257  -17.603 35.413 1.00 62.25  ? 496 ASN E CB  1 
ATOM   13748 C CG  . ASN E 1 294 ? 63.523  -17.981 36.678 1.00 62.28  ? 496 ASN E CG  1 
ATOM   13749 O OD1 . ASN E 1 294 ? 62.570  -17.322 37.071 1.00 61.02  ? 496 ASN E OD1 1 
ATOM   13750 N ND2 . ASN E 1 294 ? 63.971  -19.043 37.328 1.00 63.57  ? 496 ASN E ND2 1 
ATOM   13751 N N   . ASN E 1 295 ? 63.640  -16.183 32.673 1.00 67.31  ? 497 ASN E N   1 
ATOM   13752 C CA  . ASN E 1 295 ? 64.135  -15.389 31.557 1.00 68.07  ? 497 ASN E CA  1 
ATOM   13753 C C   . ASN E 1 295 ? 65.601  -15.028 31.805 1.00 68.95  ? 497 ASN E C   1 
ATOM   13754 O O   . ASN E 1 295 ? 66.000  -14.774 32.937 1.00 68.69  ? 497 ASN E O   1 
ATOM   13755 C CB  . ASN E 1 295 ? 63.288  -14.131 31.389 1.00 64.83  ? 497 ASN E CB  1 
ATOM   13756 C CG  . ASN E 1 295 ? 63.678  -13.330 30.173 1.00 66.06  ? 497 ASN E CG  1 
ATOM   13757 O OD1 . ASN E 1 295 ? 64.855  -13.117 29.913 1.00 66.50  ? 497 ASN E OD1 1 
ATOM   13758 N ND2 . ASN E 1 295 ? 62.687  -12.873 29.424 1.00 66.30  ? 497 ASN E ND2 1 
ATOM   13759 N N   . ASN E 1 296 ? 66.403  -15.003 30.747 1.00 67.34  ? 498 ASN E N   1 
ATOM   13760 C CA  . ASN E 1 296 ? 67.823  -14.698 30.877 1.00 68.49  ? 498 ASN E CA  1 
ATOM   13761 C C   . ASN E 1 296 ? 68.087  -13.202 30.903 1.00 69.20  ? 498 ASN E C   1 
ATOM   13762 O O   . ASN E 1 296 ? 68.628  -12.649 29.955 1.00 69.76  ? 498 ASN E O   1 
ATOM   13763 C CB  . ASN E 1 296 ? 68.589  -15.320 29.713 1.00 74.46  ? 498 ASN E CB  1 
ATOM   13764 C CG  . ASN E 1 296 ? 70.057  -14.953 29.718 1.00 74.57  ? 498 ASN E CG  1 
ATOM   13765 O OD1 . ASN E 1 296 ? 70.723  -15.022 30.747 1.00 74.28  ? 498 ASN E OD1 1 
ATOM   13766 N ND2 . ASN E 1 296 ? 70.572  -14.571 28.559 1.00 75.53  ? 498 ASN E ND2 1 
ATOM   13767 N N   . SER E 1 297 ? 67.697  -12.553 31.992 1.00 66.08  ? 499 SER E N   1 
ATOM   13768 C CA  . SER E 1 297 ? 67.891  -11.116 32.145 1.00 66.96  ? 499 SER E CA  1 
ATOM   13769 C C   . SER E 1 297 ? 67.806  -10.721 33.610 1.00 67.11  ? 499 SER E C   1 
ATOM   13770 O O   . SER E 1 297 ? 67.421  -11.528 34.451 1.00 66.79  ? 499 SER E O   1 
ATOM   13771 C CB  . SER E 1 297 ? 66.863  -10.332 31.325 1.00 62.74  ? 499 SER E CB  1 
ATOM   13772 O OG  . SER E 1 297 ? 65.591  -10.348 31.941 1.00 63.63  ? 499 SER E OG  1 
ATOM   13773 N N   . GLU E 1 298 ? 68.192  -9.490  33.918 1.00 60.51  ? 500 GLU E N   1 
ATOM   13774 C CA  . GLU E 1 298 ? 68.111  -9.003  35.284 1.00 61.02  ? 500 GLU E CA  1 
ATOM   13775 C C   . GLU E 1 298 ? 66.746  -8.356  35.490 1.00 60.25  ? 500 GLU E C   1 
ATOM   13776 O O   . GLU E 1 298 ? 66.548  -7.195  35.150 1.00 60.66  ? 500 GLU E O   1 
ATOM   13777 C CB  . GLU E 1 298 ? 69.197  -7.963  35.524 1.00 59.90  ? 500 GLU E CB  1 
ATOM   13778 C CG  . GLU E 1 298 ? 68.872  -6.982  36.631 1.00 63.97  ? 500 GLU E CG  1 
ATOM   13779 C CD  . GLU E 1 298 ? 69.186  -7.535  38.001 1.00 66.33  ? 500 GLU E CD  1 
ATOM   13780 O OE1 . GLU E 1 298 ? 70.268  -8.136  38.160 1.00 67.59  ? 500 GLU E OE1 1 
ATOM   13781 O OE2 . GLU E 1 298 ? 68.357  -7.362  38.918 1.00 66.44  ? 500 GLU E OE2 1 
ATOM   13782 N N   . PHE E 1 299 ? 65.804  -9.111  36.045 1.00 60.34  ? 501 PHE E N   1 
ATOM   13783 C CA  . PHE E 1 299 ? 64.460  -8.598  36.284 1.00 59.27  ? 501 PHE E CA  1 
ATOM   13784 C C   . PHE E 1 299 ? 64.078  -8.449  37.752 1.00 58.81  ? 501 PHE E C   1 
ATOM   13785 O O   . PHE E 1 299 ? 62.910  -8.227  38.057 1.00 59.03  ? 501 PHE E O   1 
ATOM   13786 C CB  . PHE E 1 299 ? 63.416  -9.451  35.558 1.00 59.95  ? 501 PHE E CB  1 
ATOM   13787 C CG  . PHE E 1 299 ? 63.332  -10.864 36.055 1.00 59.12  ? 501 PHE E CG  1 
ATOM   13788 C CD1 . PHE E 1 299 ? 62.605  -11.167 37.190 1.00 58.74  ? 501 PHE E CD1 1 
ATOM   13789 C CD2 . PHE E 1 299 ? 63.969  -11.888 35.384 1.00 58.80  ? 501 PHE E CD2 1 
ATOM   13790 C CE1 . PHE E 1 299 ? 62.523  -12.462 37.651 1.00 58.27  ? 501 PHE E CE1 1 
ATOM   13791 C CE2 . PHE E 1 299 ? 63.890  -13.185 35.839 1.00 58.20  ? 501 PHE E CE2 1 
ATOM   13792 C CZ  . PHE E 1 299 ? 63.165  -13.474 36.974 1.00 57.93  ? 501 PHE E CZ  1 
ATOM   13793 N N   . ALA E 1 300 ? 65.047  -8.591  38.652 1.00 59.47  ? 502 ALA E N   1 
ATOM   13794 C CA  . ALA E 1 300 ? 64.795  -8.487  40.092 1.00 58.52  ? 502 ALA E CA  1 
ATOM   13795 C C   . ALA E 1 300 ? 64.030  -7.223  40.455 1.00 58.33  ? 502 ALA E C   1 
ATOM   13796 O O   . ALA E 1 300 ? 62.912  -7.292  40.949 1.00 58.25  ? 502 ALA E O   1 
ATOM   13797 C CB  . ALA E 1 300 ? 66.099  -8.563  40.871 1.00 61.41  ? 502 ALA E CB  1 
ATOM   13798 N N   . TRP E 1 301 ? 64.643  -6.072  40.210 1.00 55.39  ? 503 TRP E N   1 
ATOM   13799 C CA  . TRP E 1 301 ? 64.007  -4.787  40.473 1.00 55.93  ? 503 TRP E CA  1 
ATOM   13800 C C   . TRP E 1 301 ? 63.092  -4.329  39.335 1.00 55.61  ? 503 TRP E C   1 
ATOM   13801 O O   . TRP E 1 301 ? 61.934  -3.979  39.597 1.00 55.59  ? 503 TRP E O   1 
ATOM   13802 C CB  . TRP E 1 301 ? 65.057  -3.716  40.776 1.00 48.45  ? 503 TRP E CB  1 
ATOM   13803 C CG  . TRP E 1 301 ? 64.448  -2.381  40.999 1.00 51.72  ? 503 TRP E CG  1 
ATOM   13804 C CD1 . TRP E 1 301 ? 64.470  -1.319  40.149 1.00 52.58  ? 503 TRP E CD1 1 
ATOM   13805 C CD2 . TRP E 1 301 ? 63.688  -1.969  42.139 1.00 53.30  ? 503 TRP E CD2 1 
ATOM   13806 N NE1 . TRP E 1 301 ? 63.785  -0.262  40.695 1.00 53.22  ? 503 TRP E NE1 1 
ATOM   13807 C CE2 . TRP E 1 301 ? 63.294  -0.637  41.917 1.00 53.58  ? 503 TRP E CE2 1 
ATOM   13808 C CE3 . TRP E 1 301 ? 63.309  -2.595  43.329 1.00 54.07  ? 503 TRP E CE3 1 
ATOM   13809 C CZ2 . TRP E 1 301 ? 62.540  0.081   42.841 1.00 54.36  ? 503 TRP E CZ2 1 
ATOM   13810 C CZ3 . TRP E 1 301 ? 62.562  -1.882  44.244 1.00 54.68  ? 503 TRP E CZ3 1 
ATOM   13811 C CH2 . TRP E 1 301 ? 62.184  -0.558  43.996 1.00 54.88  ? 503 TRP E CH2 1 
ATOM   13812 N N   . PRO E 1 302 ? 63.552  -4.297  38.073 1.00 54.72  ? 504 PRO E N   1 
ATOM   13813 C CA  . PRO E 1 302 ? 62.705  -3.704  37.021 1.00 54.45  ? 504 PRO E CA  1 
ATOM   13814 C C   . PRO E 1 302 ? 61.401  -4.443  36.778 1.00 54.89  ? 504 PRO E C   1 
ATOM   13815 O O   . PRO E 1 302 ? 60.427  -3.832  36.322 1.00 56.46  ? 504 PRO E O   1 
ATOM   13816 C CB  . PRO E 1 302 ? 63.612  -3.749  35.784 1.00 55.34  ? 504 PRO E CB  1 
ATOM   13817 C CG  . PRO E 1 302 ? 64.983  -3.758  36.328 1.00 54.66  ? 504 PRO E CG  1 
ATOM   13818 C CD  . PRO E 1 302 ? 64.888  -4.624  37.542 1.00 56.06  ? 504 PRO E CD  1 
ATOM   13819 N N   . GLY E 1 303 ? 61.353  -5.741  37.057 1.00 55.03  ? 505 GLY E N   1 
ATOM   13820 C CA  . GLY E 1 303 ? 60.160  -6.519  36.796 1.00 55.33  ? 505 GLY E CA  1 
ATOM   13821 C C   . GLY E 1 303 ? 59.338  -6.822  38.030 1.00 54.97  ? 505 GLY E C   1 
ATOM   13822 O O   . GLY E 1 303 ? 58.559  -7.779  38.038 1.00 55.90  ? 505 GLY E O   1 
ATOM   13823 N N   . ALA E 1 304 ? 59.498  -6.025  39.080 1.00 54.14  ? 506 ALA E N   1 
ATOM   13824 C CA  . ALA E 1 304 ? 58.847  -6.280  40.356 1.00 52.91  ? 506 ALA E CA  1 
ATOM   13825 C C   . ALA E 1 304 ? 57.746  -5.261  40.612 1.00 52.24  ? 506 ALA E C   1 
ATOM   13826 O O   . ALA E 1 304 ? 57.835  -4.109  40.180 1.00 53.09  ? 506 ALA E O   1 
ATOM   13827 C CB  . ALA E 1 304 ? 59.862  -6.244  41.497 1.00 52.37  ? 506 ALA E CB  1 
ATOM   13828 N N   . SER E 1 305 ? 56.707  -5.697  41.319 1.00 51.80  ? 507 SER E N   1 
ATOM   13829 C CA  . SER E 1 305 ? 55.611  -4.809  41.677 1.00 50.64  ? 507 SER E CA  1 
ATOM   13830 C C   . SER E 1 305 ? 56.056  -3.842  42.764 1.00 49.59  ? 507 SER E C   1 
ATOM   13831 O O   . SER E 1 305 ? 56.673  -4.246  43.752 1.00 49.09  ? 507 SER E O   1 
ATOM   13832 C CB  . SER E 1 305 ? 54.411  -5.622  42.152 1.00 43.94  ? 507 SER E CB  1 
ATOM   13833 O OG  . SER E 1 305 ? 53.903  -6.441  41.117 1.00 45.93  ? 507 SER E OG  1 
ATOM   13834 N N   . SER E 1 306 ? 55.730  -2.564  42.591 1.00 48.73  ? 508 SER E N   1 
ATOM   13835 C CA  . SER E 1 306 ? 56.189  -1.532  43.506 1.00 47.79  ? 508 SER E CA  1 
ATOM   13836 C C   . SER E 1 306 ? 55.074  -0.528  43.756 1.00 46.98  ? 508 SER E C   1 
ATOM   13837 O O   . SER E 1 306 ? 54.056  -0.511  43.062 1.00 47.51  ? 508 SER E O   1 
ATOM   13838 C CB  . SER E 1 306 ? 57.430  -0.812  42.963 1.00 50.10  ? 508 SER E CB  1 
ATOM   13839 O OG  . SER E 1 306 ? 57.136  -0.116  41.766 1.00 50.19  ? 508 SER E OG  1 
ATOM   13840 N N   . TRP E 1 307 ? 55.277  0.305   44.773 1.00 47.52  ? 509 TRP E N   1 
ATOM   13841 C CA  . TRP E 1 307 ? 54.416  1.449   45.031 1.00 46.96  ? 509 TRP E CA  1 
ATOM   13842 C C   . TRP E 1 307 ? 55.264  2.699   45.211 1.00 46.54  ? 509 TRP E C   1 
ATOM   13843 O O   . TRP E 1 307 ? 56.226  2.715   45.982 1.00 44.93  ? 509 TRP E O   1 
ATOM   13844 C CB  . TRP E 1 307 ? 53.511  1.233   46.255 1.00 45.46  ? 509 TRP E CB  1 
ATOM   13845 C CG  . TRP E 1 307 ? 54.206  0.809   47.518 1.00 46.13  ? 509 TRP E CG  1 
ATOM   13846 C CD1 . TRP E 1 307 ? 54.439  -0.467  47.929 1.00 46.59  ? 509 TRP E CD1 1 
ATOM   13847 C CD2 . TRP E 1 307 ? 54.737  1.661   48.541 1.00 46.50  ? 509 TRP E CD2 1 
ATOM   13848 N NE1 . TRP E 1 307 ? 55.083  -0.467  49.139 1.00 47.18  ? 509 TRP E NE1 1 
ATOM   13849 C CE2 . TRP E 1 307 ? 55.280  0.828   49.536 1.00 47.10  ? 509 TRP E CE2 1 
ATOM   13850 C CE3 . TRP E 1 307 ? 54.812  3.045   48.707 1.00 46.94  ? 509 TRP E CE3 1 
ATOM   13851 C CZ2 . TRP E 1 307 ? 55.887  1.332   50.682 1.00 47.62  ? 509 TRP E CZ2 1 
ATOM   13852 C CZ3 . TRP E 1 307 ? 55.412  3.543   49.847 1.00 47.70  ? 509 TRP E CZ3 1 
ATOM   13853 C CH2 . TRP E 1 307 ? 55.943  2.689   50.818 1.00 48.27  ? 509 TRP E CH2 1 
ATOM   13854 N N   . ALA E 1 308 ? 54.895  3.747   44.480 1.00 46.84  ? 510 ALA E N   1 
ATOM   13855 C CA  . ALA E 1 308 ? 55.613  5.011   44.478 1.00 47.19  ? 510 ALA E CA  1 
ATOM   13856 C C   . ALA E 1 308 ? 54.976  5.979   45.462 1.00 48.17  ? 510 ALA E C   1 
ATOM   13857 O O   . ALA E 1 308 ? 53.754  6.156   45.474 1.00 49.40  ? 510 ALA E O   1 
ATOM   13858 C CB  . ALA E 1 308 ? 55.631  5.631   43.080 1.00 48.17  ? 510 ALA E CB  1 
ATOM   13859 N N   . LEU E 1 309 ? 55.814  6.607   46.282 1.00 51.56  ? 511 LEU E N   1 
ATOM   13860 C CA  . LEU E 1 309 ? 55.363  7.560   47.287 1.00 52.14  ? 511 LEU E CA  1 
ATOM   13861 C C   . LEU E 1 309 ? 56.267  8.780   47.234 1.00 53.31  ? 511 LEU E C   1 
ATOM   13862 O O   . LEU E 1 309 ? 57.478  8.662   47.443 1.00 53.12  ? 511 LEU E O   1 
ATOM   13863 C CB  . LEU E 1 309 ? 55.382  6.931   48.681 1.00 48.64  ? 511 LEU E CB  1 
ATOM   13864 C CG  . LEU E 1 309 ? 54.957  7.800   49.862 1.00 48.70  ? 511 LEU E CG  1 
ATOM   13865 C CD1 . LEU E 1 309 ? 53.504  8.206   49.731 1.00 48.87  ? 511 LEU E CD1 1 
ATOM   13866 C CD2 . LEU E 1 309 ? 55.193  7.055   51.158 1.00 48.56  ? 511 LEU E CD2 1 
ATOM   13867 N N   . ASN E 1 310 ? 55.679  9.942   46.948 1.00 51.19  ? 512 ASN E N   1 
ATOM   13868 C CA  . ASN E 1 310 ? 56.413  11.206  46.861 1.00 53.02  ? 512 ASN E CA  1 
ATOM   13869 C C   . ASN E 1 310 ? 57.522  11.126  45.814 1.00 53.67  ? 512 ASN E C   1 
ATOM   13870 O O   . ASN E 1 310 ? 58.545  11.808  45.902 1.00 54.18  ? 512 ASN E O   1 
ATOM   13871 C CB  . ASN E 1 310 ? 56.968  11.612  48.229 1.00 55.86  ? 512 ASN E CB  1 
ATOM   13872 C CG  . ASN E 1 310 ? 57.455  13.045  48.261 1.00 58.13  ? 512 ASN E CG  1 
ATOM   13873 O OD1 . ASN E 1 310 ? 56.953  13.898  47.533 1.00 60.08  ? 512 ASN E OD1 1 
ATOM   13874 N ND2 . ASN E 1 310 ? 58.436  13.317  49.110 1.00 57.46  ? 512 ASN E ND2 1 
ATOM   13875 N N   . GLY E 1 311 ? 57.315  10.285  44.805 1.00 51.14  ? 513 GLY E N   1 
ATOM   13876 C CA  . GLY E 1 311 ? 58.281  10.093  43.748 1.00 51.12  ? 513 GLY E CA  1 
ATOM   13877 C C   . GLY E 1 311 ? 59.251  8.951   43.967 1.00 51.96  ? 513 GLY E C   1 
ATOM   13878 O O   . GLY E 1 311 ? 59.900  8.523   43.006 1.00 53.26  ? 513 GLY E O   1 
ATOM   13879 N N   . ARG E 1 312 ? 59.373  8.450   45.192 1.00 50.42  ? 514 ARG E N   1 
ATOM   13880 C CA  . ARG E 1 312 ? 60.264  7.341   45.496 1.00 50.81  ? 514 ARG E CA  1 
ATOM   13881 C C   . ARG E 1 312 ? 59.522  6.021   45.354 1.00 50.56  ? 514 ARG E C   1 
ATOM   13882 O O   . ARG E 1 312 ? 58.439  5.842   45.916 1.00 51.08  ? 514 ARG E O   1 
ATOM   13883 C CB  . ARG E 1 312 ? 60.832  7.461   46.911 1.00 48.13  ? 514 ARG E CB  1 
ATOM   13884 C CG  . ARG E 1 312 ? 61.796  8.611   47.106 1.00 52.13  ? 514 ARG E CG  1 
ATOM   13885 C CD  . ARG E 1 312 ? 62.178  8.750   48.567 1.00 56.18  ? 514 ARG E CD  1 
ATOM   13886 N NE  . ARG E 1 312 ? 61.025  9.081   49.397 1.00 60.37  ? 514 ARG E NE  1 
ATOM   13887 C CZ  . ARG E 1 312 ? 61.079  9.266   50.711 1.00 62.79  ? 514 ARG E CZ  1 
ATOM   13888 N NH1 . ARG E 1 312 ? 62.233  9.152   51.350 1.00 63.43  ? 514 ARG E NH1 1 
ATOM   13889 N NH2 . ARG E 1 312 ? 59.979  9.567   51.386 1.00 63.80  ? 514 ARG E NH2 1 
ATOM   13890 N N   . ASN E 1 313 ? 60.114  5.097   44.605 1.00 52.89  ? 515 ASN E N   1 
ATOM   13891 C CA  . ASN E 1 313 ? 59.536  3.780   44.390 1.00 52.10  ? 515 ASN E CA  1 
ATOM   13892 C C   . ASN E 1 313 ? 60.025  2.824   45.467 1.00 50.69  ? 515 ASN E C   1 
ATOM   13893 O O   . ASN E 1 313 ? 61.227  2.741   45.733 1.00 50.89  ? 515 ASN E O   1 
ATOM   13894 C CB  . ASN E 1 313 ? 59.898  3.240   43.007 1.00 50.86  ? 515 ASN E CB  1 
ATOM   13895 C CG  . ASN E 1 313 ? 59.212  3.995   41.894 1.00 52.47  ? 515 ASN E CG  1 
ATOM   13896 O OD1 . ASN E 1 313 ? 58.027  3.799   41.633 1.00 53.33  ? 515 ASN E OD1 1 
ATOM   13897 N ND2 . ASN E 1 313 ? 59.956  4.869   41.229 1.00 54.33  ? 515 ASN E ND2 1 
ATOM   13898 N N   . SER E 1 314 ? 59.091  2.079   46.048 1.00 51.93  ? 516 SER E N   1 
ATOM   13899 C CA  . SER E 1 314 ? 59.386  1.081   47.065 1.00 50.96  ? 516 SER E CA  1 
ATOM   13900 C C   . SER E 1 314 ? 58.821  -0.243  46.591 1.00 50.62  ? 516 SER E C   1 
ATOM   13901 O O   . SER E 1 314 ? 57.736  -0.288  46.020 1.00 50.28  ? 516 SER E O   1 
ATOM   13902 C CB  . SER E 1 314 ? 58.740  1.452   48.396 1.00 49.01  ? 516 SER E CB  1 
ATOM   13903 O OG  . SER E 1 314 ? 59.356  2.591   48.961 1.00 50.39  ? 516 SER E OG  1 
ATOM   13904 N N   . LEU E 1 315 ? 59.556  -1.323  46.813 1.00 50.46  ? 517 LEU E N   1 
ATOM   13905 C CA  . LEU E 1 315 ? 59.095  -2.636  46.403 1.00 50.77  ? 517 LEU E CA  1 
ATOM   13906 C C   . LEU E 1 315 ? 57.857  -2.991  47.202 1.00 51.20  ? 517 LEU E C   1 
ATOM   13907 O O   . LEU E 1 315 ? 57.795  -2.712  48.392 1.00 52.05  ? 517 LEU E O   1 
ATOM   13908 C CB  . LEU E 1 315 ? 60.184  -3.673  46.665 1.00 51.16  ? 517 LEU E CB  1 
ATOM   13909 C CG  . LEU E 1 315 ? 59.940  -5.073  46.111 1.00 51.93  ? 517 LEU E CG  1 
ATOM   13910 C CD1 . LEU E 1 315 ? 60.313  -5.113  44.639 1.00 51.74  ? 517 LEU E CD1 1 
ATOM   13911 C CD2 . LEU E 1 315 ? 60.732  -6.108  46.893 1.00 53.78  ? 517 LEU E CD2 1 
ATOM   13912 N N   . MET E 1 316 ? 56.876  -3.611  46.554 1.00 50.00  ? 518 MET E N   1 
ATOM   13913 C CA  . MET E 1 316 ? 55.649  -4.026  47.225 1.00 49.91  ? 518 MET E CA  1 
ATOM   13914 C C   . MET E 1 316 ? 55.889  -5.391  47.865 1.00 49.71  ? 518 MET E C   1 
ATOM   13915 O O   . MET E 1 316 ? 55.461  -6.420  47.348 1.00 49.53  ? 518 MET E O   1 
ATOM   13916 C CB  . MET E 1 316 ? 54.497  -4.095  46.223 1.00 48.58  ? 518 MET E CB  1 
ATOM   13917 C CG  . MET E 1 316 ? 53.303  -4.914  46.684 1.00 49.94  ? 518 MET E CG  1 
ATOM   13918 S SD  . MET E 1 316 ? 52.218  -4.064  47.842 1.00 52.63  ? 518 MET E SD  1 
ATOM   13919 C CE  . MET E 1 316 ? 51.364  -2.927  46.756 1.00 50.39  ? 518 MET E CE  1 
ATOM   13920 N N   . ASN E 1 317 ? 56.584  -5.382  48.998 1.00 49.01  ? 519 ASN E N   1 
ATOM   13921 C CA  . ASN E 1 317 ? 56.951  -6.593  49.718 1.00 48.42  ? 519 ASN E CA  1 
ATOM   13922 C C   . ASN E 1 317 ? 56.443  -6.580  51.150 1.00 48.20  ? 519 ASN E C   1 
ATOM   13923 O O   . ASN E 1 317 ? 56.640  -5.602  51.858 1.00 48.98  ? 519 ASN E O   1 
ATOM   13924 C CB  . ASN E 1 317 ? 58.476  -6.701  49.727 1.00 48.22  ? 519 ASN E CB  1 
ATOM   13925 C CG  . ASN E 1 317 ? 58.978  -7.885  50.518 1.00 48.66  ? 519 ASN E CG  1 
ATOM   13926 O OD1 . ASN E 1 317 ? 58.388  -8.962  50.489 1.00 51.01  ? 519 ASN E OD1 1 
ATOM   13927 N ND2 . ASN E 1 317 ? 60.086  -7.696  51.220 1.00 47.40  ? 519 ASN E ND2 1 
ATOM   13928 N N   . PRO E 1 318 ? 55.831  -7.684  51.607 1.00 48.16  ? 520 PRO E N   1 
ATOM   13929 C CA  . PRO E 1 318 ? 55.091  -8.745  50.910 1.00 47.97  ? 520 PRO E CA  1 
ATOM   13930 C C   . PRO E 1 318 ? 53.817  -8.255  50.227 1.00 48.51  ? 520 PRO E C   1 
ATOM   13931 O O   . PRO E 1 318 ? 53.475  -8.742  49.154 1.00 48.27  ? 520 PRO E O   1 
ATOM   13932 C CB  . PRO E 1 318 ? 54.758  -9.738  52.025 1.00 46.48  ? 520 PRO E CB  1 
ATOM   13933 C CG  . PRO E 1 318 ? 54.822  -8.948  53.277 1.00 46.49  ? 520 PRO E CG  1 
ATOM   13934 C CD  . PRO E 1 318 ? 55.906  -7.943  53.054 1.00 47.31  ? 520 PRO E CD  1 
ATOM   13935 N N   . GLY E 1 319 ? 53.107  -7.327  50.859 1.00 47.35  ? 521 GLY E N   1 
ATOM   13936 C CA  . GLY E 1 319 ? 51.882  -6.802  50.291 1.00 48.37  ? 521 GLY E CA  1 
ATOM   13937 C C   . GLY E 1 319 ? 50.710  -7.698  50.611 1.00 49.19  ? 521 GLY E C   1 
ATOM   13938 O O   . GLY E 1 319 ? 50.822  -8.572  51.463 1.00 49.68  ? 521 GLY E O   1 
ATOM   13939 N N   . PRO E 1 320 ? 49.575  -7.481  49.932 1.00 48.34  ? 522 PRO E N   1 
ATOM   13940 C CA  . PRO E 1 320 ? 48.328  -8.234  50.108 1.00 48.07  ? 522 PRO E CA  1 
ATOM   13941 C C   . PRO E 1 320 ? 48.523  -9.740  50.283 1.00 47.78  ? 522 PRO E C   1 
ATOM   13942 O O   . PRO E 1 320 ? 49.277  -10.371 49.545 1.00 48.86  ? 522 PRO E O   1 
ATOM   13943 C CB  . PRO E 1 320 ? 47.577  -7.954  48.810 1.00 45.64  ? 522 PRO E CB  1 
ATOM   13944 C CG  . PRO E 1 320 ? 48.038  -6.601  48.409 1.00 46.96  ? 522 PRO E CG  1 
ATOM   13945 C CD  . PRO E 1 320 ? 49.459  -6.465  48.874 1.00 46.38  ? 522 PRO E CD  1 
ATOM   13946 N N   . ALA E 1 321 ? 47.828  -10.308 51.260 1.00 44.26  ? 523 ALA E N   1 
ATOM   13947 C CA  . ALA E 1 321 ? 47.917  -11.736 51.529 1.00 44.06  ? 523 ALA E CA  1 
ATOM   13948 C C   . ALA E 1 321 ? 47.265  -12.504 50.389 1.00 44.17  ? 523 ALA E C   1 
ATOM   13949 O O   . ALA E 1 321 ? 46.068  -12.349 50.129 1.00 43.86  ? 523 ALA E O   1 
ATOM   13950 C CB  . ALA E 1 321 ? 47.248  -12.072 52.858 1.00 39.73  ? 523 ALA E CB  1 
ATOM   13951 N N   . MET E 1 322 ? 48.053  -13.337 49.717 1.00 42.80  ? 524 MET E N   1 
ATOM   13952 C CA  . MET E 1 322 ? 47.596  -14.106 48.573 1.00 43.63  ? 524 MET E CA  1 
ATOM   13953 C C   . MET E 1 322 ? 48.286  -15.459 48.590 1.00 44.05  ? 524 MET E C   1 
ATOM   13954 O O   . MET E 1 322 ? 49.360  -15.614 49.174 1.00 45.64  ? 524 MET E O   1 
ATOM   13955 C CB  . MET E 1 322 ? 47.894  -13.384 47.256 1.00 39.76  ? 524 MET E CB  1 
ATOM   13956 C CG  . MET E 1 322 ? 47.101  -12.111 47.047 1.00 42.46  ? 524 MET E CG  1 
ATOM   13957 S SD  . MET E 1 322 ? 47.584  -11.272 45.535 1.00 46.05  ? 524 MET E SD  1 
ATOM   13958 C CE  . MET E 1 322 ? 49.163  -10.626 46.061 1.00 48.13  ? 524 MET E CE  1 
ATOM   13959 N N   . ALA E 1 323 ? 47.658  -16.437 47.946 1.00 43.95  ? 525 ALA E N   1 
ATOM   13960 C CA  . ALA E 1 323 ? 48.266  -17.753 47.828 1.00 44.95  ? 525 ALA E CA  1 
ATOM   13961 C C   . ALA E 1 323 ? 49.547  -17.662 47.012 1.00 46.32  ? 525 ALA E C   1 
ATOM   13962 O O   . ALA E 1 323 ? 49.589  -17.003 45.970 1.00 46.78  ? 525 ALA E O   1 
ATOM   13963 C CB  . ALA E 1 323 ? 47.291  -18.731 47.181 1.00 44.91  ? 525 ALA E CB  1 
ATOM   13964 N N   . SER E 1 324 ? 50.596  -18.331 47.491 1.00 47.89  ? 526 SER E N   1 
ATOM   13965 C CA  . SER E 1 324 ? 51.901  -18.211 46.854 1.00 49.68  ? 526 SER E CA  1 
ATOM   13966 C C   . SER E 1 324 ? 51.929  -18.874 45.485 1.00 50.85  ? 526 SER E C   1 
ATOM   13967 O O   . SER E 1 324 ? 52.659  -18.425 44.596 1.00 51.00  ? 526 SER E O   1 
ATOM   13968 C CB  . SER E 1 324 ? 52.977  -18.811 47.756 1.00 49.71  ? 526 SER E CB  1 
ATOM   13969 O OG  . SER E 1 324 ? 53.072  -18.094 48.974 1.00 52.44  ? 526 SER E OG  1 
ATOM   13970 N N   . HIS E 1 325 ? 51.153  -19.936 45.297 1.00 52.04  ? 527 HIS E N   1 
ATOM   13971 C CA  . HIS E 1 325 ? 51.156  -20.663 44.038 1.00 54.52  ? 527 HIS E CA  1 
ATOM   13972 C C   . HIS E 1 325 ? 49.852  -21.432 43.916 1.00 56.06  ? 527 HIS E C   1 
ATOM   13973 O O   . HIS E 1 325 ? 49.135  -21.631 44.899 1.00 56.08  ? 527 HIS E O   1 
ATOM   13974 C CB  . HIS E 1 325 ? 52.355  -21.609 43.949 1.00 59.74  ? 527 HIS E CB  1 
ATOM   13975 C CG  . HIS E 1 325 ? 52.390  -22.636 45.036 1.00 60.56  ? 527 HIS E CG  1 
ATOM   13976 N ND1 . HIS E 1 325 ? 51.594  -23.760 45.023 1.00 61.12  ? 527 HIS E ND1 1 
ATOM   13977 C CD2 . HIS E 1 325 ? 53.123  -22.708 46.172 1.00 60.59  ? 527 HIS E CD2 1 
ATOM   13978 C CE1 . HIS E 1 325 ? 51.835  -24.481 46.102 1.00 60.18  ? 527 HIS E CE1 1 
ATOM   13979 N NE2 . HIS E 1 325 ? 52.759  -23.865 46.816 1.00 60.12  ? 527 HIS E NE2 1 
ATOM   13980 N N   . LYS E 1 326 ? 49.583  -21.947 42.721 1.00 57.80  ? 528 LYS E N   1 
ATOM   13981 C CA  . LYS E 1 326 ? 48.394  -22.761 42.504 1.00 60.56  ? 528 LYS E CA  1 
ATOM   13982 C C   . LYS E 1 326 ? 48.687  -24.165 43.019 1.00 62.56  ? 528 LYS E C   1 
ATOM   13983 O O   . LYS E 1 326 ? 49.846  -24.554 43.161 1.00 62.08  ? 528 LYS E O   1 
ATOM   13984 C CB  . LYS E 1 326 ? 48.019  -22.810 41.024 1.00 53.12  ? 528 LYS E CB  1 
ATOM   13985 C CG  . LYS E 1 326 ? 47.459  -21.506 40.483 1.00 53.72  ? 528 LYS E CG  1 
ATOM   13986 C CD  . LYS E 1 326 ? 47.011  -21.650 39.041 1.00 55.90  ? 528 LYS E CD  1 
ATOM   13987 C CE  . LYS E 1 326 ? 48.168  -22.035 38.139 1.00 56.30  ? 528 LYS E CE  1 
ATOM   13988 N NZ  . LYS E 1 326 ? 47.726  -22.239 36.733 1.00 56.70  ? 528 LYS E NZ  1 
ATOM   13989 N N   . GLU E 1 327 ? 47.648  -24.947 43.275 1.00 61.58  ? 529 GLU E N   1 
ATOM   13990 C CA  . GLU E 1 327 ? 47.867  -26.288 43.790 1.00 65.30  ? 529 GLU E CA  1 
ATOM   13991 C C   . GLU E 1 327 ? 48.646  -27.117 42.786 1.00 66.01  ? 529 GLU E C   1 
ATOM   13992 O O   . GLU E 1 327 ? 48.402  -27.044 41.584 1.00 66.05  ? 529 GLU E O   1 
ATOM   13993 C CB  . GLU E 1 327 ? 46.540  -26.966 44.110 1.00 61.94  ? 529 GLU E CB  1 
ATOM   13994 C CG  . GLU E 1 327 ? 46.675  -28.146 45.053 1.00 67.72  ? 529 GLU E CG  1 
ATOM   13995 C CD  . GLU E 1 327 ? 45.368  -28.499 45.732 1.00 70.73  ? 529 GLU E CD  1 
ATOM   13996 O OE1 . GLU E 1 327 ? 45.347  -28.561 46.978 1.00 71.12  ? 529 GLU E OE1 1 
ATOM   13997 O OE2 . GLU E 1 327 ? 44.361  -28.700 45.024 1.00 72.68  ? 529 GLU E OE2 1 
ATOM   13998 N N   . GLY E 1 328 ? 49.586  -27.907 43.292 1.00 67.22  ? 530 GLY E N   1 
ATOM   13999 C CA  . GLY E 1 328 ? 50.410  -28.752 42.452 1.00 67.95  ? 530 GLY E CA  1 
ATOM   14000 C C   . GLY E 1 328 ? 51.554  -28.044 41.751 1.00 68.44  ? 530 GLY E C   1 
ATOM   14001 O O   . GLY E 1 328 ? 52.165  -28.612 40.849 1.00 69.40  ? 530 GLY E O   1 
ATOM   14002 N N   . GLU E 1 329 ? 51.854  -26.812 42.151 1.00 70.18  ? 531 GLU E N   1 
ATOM   14003 C CA  . GLU E 1 329 ? 52.942  -26.068 41.516 1.00 69.70  ? 531 GLU E CA  1 
ATOM   14004 C C   . GLU E 1 329 ? 53.918  -25.458 42.515 1.00 68.00  ? 531 GLU E C   1 
ATOM   14005 O O   . GLU E 1 329 ? 53.966  -24.247 42.698 1.00 67.98  ? 531 GLU E O   1 
ATOM   14006 C CB  . GLU E 1 329 ? 52.375  -24.984 40.603 1.00 63.06  ? 531 GLU E CB  1 
ATOM   14007 C CG  . GLU E 1 329 ? 51.561  -25.541 39.452 1.00 67.11  ? 531 GLU E CG  1 
ATOM   14008 C CD  . GLU E 1 329 ? 51.078  -24.470 38.504 1.00 70.65  ? 531 GLU E CD  1 
ATOM   14009 O OE1 . GLU E 1 329 ? 51.089  -23.287 38.892 1.00 72.82  ? 531 GLU E OE1 1 
ATOM   14010 O OE2 . GLU E 1 329 ? 50.685  -24.815 37.371 1.00 71.64  ? 531 GLU E OE2 1 
ATOM   14011 N N   . ASP E 1 330 ? 54.698  -26.321 43.153 1.00 74.65  ? 532 ASP E N   1 
ATOM   14012 C CA  . ASP E 1 330 ? 55.654  -25.925 44.185 1.00 73.00  ? 532 ASP E CA  1 
ATOM   14013 C C   . ASP E 1 330 ? 56.935  -25.206 43.752 1.00 69.81  ? 532 ASP E C   1 
ATOM   14014 O O   . ASP E 1 330 ? 57.511  -24.459 44.538 1.00 68.79  ? 532 ASP E O   1 
ATOM   14015 C CB  . ASP E 1 330 ? 56.019  -27.148 45.031 1.00 71.13  ? 532 ASP E CB  1 
ATOM   14016 C CG  . ASP E 1 330 ? 56.175  -28.408 44.195 1.00 76.23  ? 532 ASP E CG  1 
ATOM   14017 O OD1 . ASP E 1 330 ? 56.502  -28.295 42.995 1.00 78.73  ? 532 ASP E OD1 1 
ATOM   14018 O OD2 . ASP E 1 330 ? 55.966  -29.512 44.738 1.00 79.37  ? 532 ASP E OD2 1 
ATOM   14019 N N   . ARG E 1 331 ? 57.400  -25.422 42.530 1.00 68.65  ? 533 ARG E N   1 
ATOM   14020 C CA  . ARG E 1 331 ? 58.638  -24.765 42.118 1.00 65.03  ? 533 ARG E CA  1 
ATOM   14021 C C   . ARG E 1 331 ? 58.551  -23.236 42.091 1.00 63.68  ? 533 ARG E C   1 
ATOM   14022 O O   . ARG E 1 331 ? 59.493  -22.553 42.485 1.00 62.90  ? 533 ARG E O   1 
ATOM   14023 C CB  . ARG E 1 331 ? 59.190  -25.336 40.805 1.00 61.21  ? 533 ARG E CB  1 
ATOM   14024 C CG  . ARG E 1 331 ? 58.356  -25.082 39.567 1.00 59.04  ? 533 ARG E CG  1 
ATOM   14025 C CD  . ARG E 1 331 ? 59.064  -25.644 38.345 1.00 59.19  ? 533 ARG E CD  1 
ATOM   14026 N NE  . ARG E 1 331 ? 58.363  -25.342 37.102 1.00 59.70  ? 533 ARG E NE  1 
ATOM   14027 C CZ  . ARG E 1 331 ? 57.383  -26.085 36.599 1.00 59.82  ? 533 ARG E CZ  1 
ATOM   14028 N NH1 . ARG E 1 331 ? 56.983  -27.174 37.237 1.00 60.32  ? 533 ARG E NH1 1 
ATOM   14029 N NH2 . ARG E 1 331 ? 56.799  -25.736 35.462 1.00 58.11  ? 533 ARG E NH2 1 
ATOM   14030 N N   . PHE E 1 332 ? 57.429  -22.703 41.622 1.00 61.70  ? 534 PHE E N   1 
ATOM   14031 C CA  . PHE E 1 332 ? 57.233  -21.254 41.555 1.00 59.22  ? 534 PHE E CA  1 
ATOM   14032 C C   . PHE E 1 332 ? 56.964  -20.552 42.889 1.00 58.24  ? 534 PHE E C   1 
ATOM   14033 O O   . PHE E 1 332 ? 56.395  -21.137 43.806 1.00 59.24  ? 534 PHE E O   1 
ATOM   14034 C CB  . PHE E 1 332 ? 56.136  -20.924 40.553 1.00 56.50  ? 534 PHE E CB  1 
ATOM   14035 C CG  . PHE E 1 332 ? 56.409  -21.447 39.183 1.00 56.72  ? 534 PHE E CG  1 
ATOM   14036 C CD1 . PHE E 1 332 ? 57.294  -20.797 38.348 1.00 57.18  ? 534 PHE E CD1 1 
ATOM   14037 C CD2 . PHE E 1 332 ? 55.794  -22.597 38.737 1.00 57.35  ? 534 PHE E CD2 1 
ATOM   14038 C CE1 . PHE E 1 332 ? 57.554  -21.278 37.085 1.00 57.36  ? 534 PHE E CE1 1 
ATOM   14039 C CE2 . PHE E 1 332 ? 56.048  -23.085 37.476 1.00 57.18  ? 534 PHE E CE2 1 
ATOM   14040 C CZ  . PHE E 1 332 ? 56.928  -22.424 36.647 1.00 57.09  ? 534 PHE E CZ  1 
ATOM   14041 N N   . PHE E 1 333 ? 57.380  -19.291 42.980 1.00 57.45  ? 535 PHE E N   1 
ATOM   14042 C CA  . PHE E 1 333 ? 57.167  -18.483 44.178 1.00 55.57  ? 535 PHE E CA  1 
ATOM   14043 C C   . PHE E 1 333 ? 57.056  -17.011 43.802 1.00 54.59  ? 535 PHE E C   1 
ATOM   14044 O O   . PHE E 1 333 ? 57.784  -16.540 42.939 1.00 54.10  ? 535 PHE E O   1 
ATOM   14045 C CB  . PHE E 1 333 ? 58.279  -18.709 45.210 1.00 54.73  ? 535 PHE E CB  1 
ATOM   14046 C CG  . PHE E 1 333 ? 59.593  -18.068 44.860 1.00 54.98  ? 535 PHE E CG  1 
ATOM   14047 C CD1 . PHE E 1 333 ? 59.969  -16.872 45.445 1.00 54.02  ? 535 PHE E CD1 1 
ATOM   14048 C CD2 . PHE E 1 333 ? 60.463  -18.671 43.972 1.00 55.23  ? 535 PHE E CD2 1 
ATOM   14049 C CE1 . PHE E 1 333 ? 61.179  -16.283 45.138 1.00 52.89  ? 535 PHE E CE1 1 
ATOM   14050 C CE2 . PHE E 1 333 ? 61.676  -18.086 43.660 1.00 54.16  ? 535 PHE E CE2 1 
ATOM   14051 C CZ  . PHE E 1 333 ? 62.035  -16.891 44.245 1.00 53.05  ? 535 PHE E CZ  1 
ATOM   14052 N N   . PRO E 1 334 ? 56.145  -16.273 44.448 1.00 51.22  ? 536 PRO E N   1 
ATOM   14053 C CA  . PRO E 1 334 ? 56.024  -14.863 44.074 1.00 50.82  ? 536 PRO E CA  1 
ATOM   14054 C C   . PRO E 1 334 ? 57.308  -14.114 44.381 1.00 50.59  ? 536 PRO E C   1 
ATOM   14055 O O   . PRO E 1 334 ? 57.964  -14.350 45.398 1.00 50.38  ? 536 PRO E O   1 
ATOM   14056 C CB  . PRO E 1 334 ? 54.858  -14.366 44.936 1.00 50.95  ? 536 PRO E CB  1 
ATOM   14057 C CG  . PRO E 1 334 ? 54.852  -15.280 46.110 1.00 51.02  ? 536 PRO E CG  1 
ATOM   14058 C CD  . PRO E 1 334 ? 55.264  -16.622 45.575 1.00 50.94  ? 536 PRO E CD  1 
ATOM   14059 N N   . LEU E 1 335 ? 57.665  -13.206 43.473 1.00 50.49  ? 537 LEU E N   1 
ATOM   14060 C CA  . LEU E 1 335 ? 58.948  -12.518 43.519 1.00 50.89  ? 537 LEU E CA  1 
ATOM   14061 C C   . LEU E 1 335 ? 59.151  -11.838 44.867 1.00 51.85  ? 537 LEU E C   1 
ATOM   14062 O O   . LEU E 1 335 ? 60.010  -12.249 45.652 1.00 52.14  ? 537 LEU E O   1 
ATOM   14063 C CB  . LEU E 1 335 ? 59.039  -11.504 42.377 1.00 51.34  ? 537 LEU E CB  1 
ATOM   14064 C CG  . LEU E 1 335 ? 60.384  -10.848 42.063 1.00 51.24  ? 537 LEU E CG  1 
ATOM   14065 C CD1 . LEU E 1 335 ? 60.470  -10.544 40.581 1.00 51.30  ? 537 LEU E CD1 1 
ATOM   14066 C CD2 . LEU E 1 335 ? 60.594  -9.581  42.870 1.00 52.15  ? 537 LEU E CD2 1 
ATOM   14067 N N   . SER E 1 336 ? 58.374  -10.794 45.139 1.00 49.16  ? 538 SER E N   1 
ATOM   14068 C CA  . SER E 1 336 ? 58.425  -10.086 46.408 1.00 50.58  ? 538 SER E CA  1 
ATOM   14069 C C   . SER E 1 336 ? 57.328  -10.511 47.378 1.00 50.81  ? 538 SER E C   1 
ATOM   14070 O O   . SER E 1 336 ? 57.213  -9.923  48.455 1.00 51.19  ? 538 SER E O   1 
ATOM   14071 C CB  . SER E 1 336 ? 58.355  -8.578  46.170 1.00 50.22  ? 538 SER E CB  1 
ATOM   14072 O OG  . SER E 1 336 ? 57.130  -8.212  45.563 1.00 53.15  ? 538 SER E OG  1 
ATOM   14073 N N   . GLY E 1 337 ? 56.515  -11.503 47.024 1.00 48.53  ? 539 GLY E N   1 
ATOM   14074 C CA  . GLY E 1 337 ? 55.327  -11.804 47.803 1.00 49.67  ? 539 GLY E CA  1 
ATOM   14075 C C   . GLY E 1 337 ? 55.501  -12.760 48.965 1.00 50.26  ? 539 GLY E C   1 
ATOM   14076 O O   . GLY E 1 337 ? 54.510  -13.087 49.622 1.00 52.62  ? 539 GLY E O   1 
ATOM   14077 N N   . SER E 1 338 ? 56.718  -13.212 49.245 1.00 50.09  ? 540 SER E N   1 
ATOM   14078 C CA  . SER E 1 338 ? 56.953  -14.166 50.317 1.00 50.12  ? 540 SER E CA  1 
ATOM   14079 C C   . SER E 1 338 ? 57.967  -13.618 51.311 1.00 48.89  ? 540 SER E C   1 
ATOM   14080 O O   . SER E 1 338 ? 58.855  -12.836 50.963 1.00 48.87  ? 540 SER E O   1 
ATOM   14081 C CB  . SER E 1 338 ? 57.445  -15.510 49.768 1.00 51.35  ? 540 SER E CB  1 
ATOM   14082 O OG  . SER E 1 338 ? 56.454  -16.132 48.970 1.00 52.90  ? 540 SER E OG  1 
ATOM   14083 N N   . LEU E 1 339 ? 57.816  -14.042 52.563 1.00 50.72  ? 541 LEU E N   1 
ATOM   14084 C CA  . LEU E 1 339 ? 58.793  -13.733 53.596 1.00 49.53  ? 541 LEU E CA  1 
ATOM   14085 C C   . LEU E 1 339 ? 59.972  -14.687 53.480 1.00 49.31  ? 541 LEU E C   1 
ATOM   14086 O O   . LEU E 1 339 ? 59.808  -15.906 53.591 1.00 49.80  ? 541 LEU E O   1 
ATOM   14087 C CB  . LEU E 1 339 ? 58.164  -13.845 54.983 1.00 51.01  ? 541 LEU E CB  1 
ATOM   14088 C CG  . LEU E 1 339 ? 57.048  -12.862 55.323 1.00 50.09  ? 541 LEU E CG  1 
ATOM   14089 C CD1 . LEU E 1 339 ? 56.445  -13.205 56.669 1.00 49.62  ? 541 LEU E CD1 1 
ATOM   14090 C CD2 . LEU E 1 339 ? 57.580  -11.445 55.322 1.00 49.47  ? 541 LEU E CD2 1 
ATOM   14091 N N   . ILE E 1 340 ? 61.161  -14.137 53.268 1.00 48.87  ? 542 ILE E N   1 
ATOM   14092 C CA  . ILE E 1 340 ? 62.356  -14.933 53.027 1.00 49.26  ? 542 ILE E CA  1 
ATOM   14093 C C   . ILE E 1 340 ? 63.290  -14.744 54.212 1.00 48.72  ? 542 ILE E C   1 
ATOM   14094 O O   . ILE E 1 340 ? 63.687  -13.614 54.523 1.00 47.72  ? 542 ILE E O   1 
ATOM   14095 C CB  . ILE E 1 340 ? 63.043  -14.541 51.713 1.00 46.11  ? 542 ILE E CB  1 
ATOM   14096 C CG1 . ILE E 1 340 ? 62.073  -14.707 50.547 1.00 48.95  ? 542 ILE E CG1 1 
ATOM   14097 C CG2 . ILE E 1 340 ? 64.249  -15.426 51.480 1.00 47.39  ? 542 ILE E CG2 1 
ATOM   14098 C CD1 . ILE E 1 340 ? 62.557  -14.079 49.263 1.00 50.79  ? 542 ILE E CD1 1 
ATOM   14099 N N   . PHE E 1 341 ? 63.638  -15.843 54.871 1.00 49.75  ? 543 PHE E N   1 
ATOM   14100 C CA  . PHE E 1 341 ? 64.480  -15.785 56.059 1.00 49.62  ? 543 PHE E CA  1 
ATOM   14101 C C   . PHE E 1 341 ? 65.904  -16.229 55.754 1.00 49.03  ? 543 PHE E C   1 
ATOM   14102 O O   . PHE E 1 341 ? 66.148  -17.396 55.459 1.00 47.86  ? 543 PHE E O   1 
ATOM   14103 C CB  . PHE E 1 341 ? 63.890  -16.654 57.167 1.00 50.27  ? 543 PHE E CB  1 
ATOM   14104 C CG  . PHE E 1 341 ? 62.542  -16.199 57.637 1.00 50.76  ? 543 PHE E CG  1 
ATOM   14105 C CD1 . PHE E 1 341 ? 62.425  -15.196 58.578 1.00 50.84  ? 543 PHE E CD1 1 
ATOM   14106 C CD2 . PHE E 1 341 ? 61.391  -16.781 57.141 1.00 50.61  ? 543 PHE E CD2 1 
ATOM   14107 C CE1 . PHE E 1 341 ? 61.185  -14.779 59.014 1.00 50.39  ? 543 PHE E CE1 1 
ATOM   14108 C CE2 . PHE E 1 341 ? 60.149  -16.369 57.571 1.00 50.29  ? 543 PHE E CE2 1 
ATOM   14109 C CZ  . PHE E 1 341 ? 60.045  -15.367 58.509 1.00 50.15  ? 543 PHE E CZ  1 
ATOM   14110 N N   . VAL E 1 356 ? 68.691  -19.540 52.197 1.00 51.36  ? 558 VAL E N   1 
ATOM   14111 C CA  . VAL E 1 356 ? 67.533  -18.827 52.717 1.00 50.55  ? 558 VAL E CA  1 
ATOM   14112 C C   . VAL E 1 356 ? 66.319  -19.746 52.730 1.00 50.40  ? 558 VAL E C   1 
ATOM   14113 O O   . VAL E 1 356 ? 66.364  -20.851 52.192 1.00 50.40  ? 558 VAL E O   1 
ATOM   14114 C CB  . VAL E 1 356 ? 67.247  -17.563 51.899 1.00 50.13  ? 558 VAL E CB  1 
ATOM   14115 C CG1 . VAL E 1 356 ? 68.426  -16.609 51.975 1.00 53.68  ? 558 VAL E CG1 1 
ATOM   14116 C CG2 . VAL E 1 356 ? 66.935  -17.925 50.457 1.00 50.15  ? 558 VAL E CG2 1 
ATOM   14117 N N   . MET E 1 357 ? 65.230  -19.282 53.341 1.00 50.52  ? 559 MET E N   1 
ATOM   14118 C CA  . MET E 1 357 ? 63.995  -20.052 53.461 1.00 50.79  ? 559 MET E CA  1 
ATOM   14119 C C   . MET E 1 357 ? 62.847  -19.213 52.915 1.00 50.63  ? 559 MET E C   1 
ATOM   14120 O O   . MET E 1 357 ? 62.549  -18.141 53.449 1.00 50.08  ? 559 MET E O   1 
ATOM   14121 C CB  . MET E 1 357 ? 63.737  -20.444 54.914 1.00 50.67  ? 559 MET E CB  1 
ATOM   14122 C CG  . MET E 1 357 ? 64.776  -21.379 55.496 1.00 54.90  ? 559 MET E CG  1 
ATOM   14123 S SD  . MET E 1 357 ? 64.389  -21.858 57.186 1.00 59.35  ? 559 MET E SD  1 
ATOM   14124 C CE  . MET E 1 357 ? 64.768  -20.345 58.060 1.00 59.05  ? 559 MET E CE  1 
ATOM   14125 N N   . ILE E 1 358 ? 62.199  -19.704 51.865 1.00 51.31  ? 560 ILE E N   1 
ATOM   14126 C CA  . ILE E 1 358 ? 61.096  -18.994 51.229 1.00 51.26  ? 560 ILE E CA  1 
ATOM   14127 C C   . ILE E 1 358 ? 59.786  -19.604 51.709 1.00 53.31  ? 560 ILE E C   1 
ATOM   14128 O O   . ILE E 1 358 ? 59.507  -20.779 51.449 1.00 53.30  ? 560 ILE E O   1 
ATOM   14129 C CB  . ILE E 1 358 ? 61.206  -19.061 49.700 1.00 53.94  ? 560 ILE E CB  1 
ATOM   14130 C CG1 . ILE E 1 358 ? 62.478  -18.359 49.231 1.00 52.47  ? 560 ILE E CG1 1 
ATOM   14131 C CG2 . ILE E 1 358 ? 59.988  -18.432 49.053 1.00 52.93  ? 560 ILE E CG2 1 
ATOM   14132 C CD1 . ILE E 1 358 ? 62.794  -18.595 47.780 1.00 50.63  ? 560 ILE E CD1 1 
ATOM   14133 N N   . THR E 1 359 ? 58.986  -18.812 52.414 1.00 49.37  ? 561 THR E N   1 
ATOM   14134 C CA  . THR E 1 359 ? 57.710  -19.293 52.915 1.00 52.42  ? 561 THR E CA  1 
ATOM   14135 C C   . THR E 1 359 ? 56.652  -19.272 51.816 1.00 55.77  ? 561 THR E C   1 
ATOM   14136 O O   . THR E 1 359 ? 56.729  -18.506 50.853 1.00 55.24  ? 561 THR E O   1 
ATOM   14137 C CB  . THR E 1 359 ? 57.241  -18.452 54.099 1.00 52.70  ? 561 THR E CB  1 
ATOM   14138 O OG1 . THR E 1 359 ? 57.098  -17.089 53.688 1.00 54.22  ? 561 THR E OG1 1 
ATOM   14139 C CG2 . THR E 1 359 ? 58.246  -18.526 55.231 1.00 52.14  ? 561 THR E CG2 1 
ATOM   14140 N N   . ASN E 1 360 ? 55.583  -20.028 52.014 1.00 53.46  ? 562 ASN E N   1 
ATOM   14141 C CA  . ASN E 1 360 ? 54.482  -20.020 51.060 1.00 57.65  ? 562 ASN E CA  1 
ATOM   14142 C C   . ASN E 1 360 ? 53.170  -19.893 51.819 1.00 59.27  ? 562 ASN E C   1 
ATOM   14143 O O   . ASN E 1 360 ? 53.121  -20.118 53.026 1.00 60.53  ? 562 ASN E O   1 
ATOM   14144 C CB  . ASN E 1 360 ? 54.483  -21.282 50.209 1.00 53.83  ? 562 ASN E CB  1 
ATOM   14145 C CG  . ASN E 1 360 ? 54.752  -22.519 51.020 1.00 58.01  ? 562 ASN E CG  1 
ATOM   14146 O OD1 . ASN E 1 360 ? 55.148  -22.432 52.179 1.00 62.33  ? 562 ASN E OD1 1 
ATOM   14147 N ND2 . ASN E 1 360 ? 54.547  -23.682 50.417 1.00 60.13  ? 562 ASN E ND2 1 
ATOM   14148 N N   . GLU E 1 361 ? 52.104  -19.532 51.124 1.00 55.19  ? 563 GLU E N   1 
ATOM   14149 C CA  . GLU E 1 361 ? 50.824  -19.420 51.795 1.00 57.20  ? 563 GLU E CA  1 
ATOM   14150 C C   . GLU E 1 361 ? 49.800  -20.198 50.995 1.00 56.10  ? 563 GLU E C   1 
ATOM   14151 O O   . GLU E 1 361 ? 48.851  -19.640 50.459 1.00 57.74  ? 563 GLU E O   1 
ATOM   14152 C CB  . GLU E 1 361 ? 50.406  -17.955 51.920 1.00 49.50  ? 563 GLU E CB  1 
ATOM   14153 C CG  . GLU E 1 361 ? 51.425  -17.064 52.618 1.00 55.26  ? 563 GLU E CG  1 
ATOM   14154 C CD  . GLU E 1 361 ? 51.468  -17.265 54.124 1.00 58.32  ? 563 GLU E CD  1 
ATOM   14155 O OE1 . GLU E 1 361 ? 50.425  -17.611 54.715 1.00 58.49  ? 563 GLU E OE1 1 
ATOM   14156 O OE2 . GLU E 1 361 ? 52.548  -17.063 54.720 1.00 60.79  ? 563 GLU E OE2 1 
ATOM   14157 N N   . GLU E 1 362 ? 50.018  -21.504 50.929 1.00 58.72  ? 564 GLU E N   1 
ATOM   14158 C CA  . GLU E 1 362 ? 49.143  -22.438 50.236 1.00 57.29  ? 564 GLU E CA  1 
ATOM   14159 C C   . GLU E 1 362 ? 47.774  -22.545 50.898 1.00 55.20  ? 564 GLU E C   1 
ATOM   14160 O O   . GLU E 1 362 ? 46.760  -22.687 50.228 1.00 54.83  ? 564 GLU E O   1 
ATOM   14161 C CB  . GLU E 1 362 ? 49.789  -23.819 50.144 1.00 61.68  ? 564 GLU E CB  1 
ATOM   14162 C CG  . GLU E 1 362 ? 50.300  -24.340 51.471 1.00 65.84  ? 564 GLU E CG  1 
ATOM   14163 C CD  . GLU E 1 362 ? 49.843  -25.754 51.747 1.00 68.12  ? 564 GLU E CD  1 
ATOM   14164 O OE1 . GLU E 1 362 ? 48.968  -26.250 51.008 1.00 68.86  ? 564 GLU E OE1 1 
ATOM   14165 O OE2 . GLU E 1 362 ? 50.356  -26.368 52.705 1.00 69.28  ? 564 GLU E OE2 1 
ATOM   14166 N N   . GLU E 1 363 ? 47.761  -22.460 52.223 1.00 56.30  ? 565 GLU E N   1 
ATOM   14167 C CA  . GLU E 1 363 ? 46.548  -22.612 53.019 1.00 54.59  ? 565 GLU E CA  1 
ATOM   14168 C C   . GLU E 1 363 ? 45.456  -21.610 52.689 1.00 50.83  ? 565 GLU E C   1 
ATOM   14169 O O   . GLU E 1 363 ? 44.278  -21.944 52.715 1.00 50.69  ? 565 GLU E O   1 
ATOM   14170 C CB  . GLU E 1 363 ? 46.874  -22.495 54.510 1.00 52.09  ? 565 GLU E CB  1 
ATOM   14171 C CG  . GLU E 1 363 ? 47.820  -23.553 55.046 1.00 59.91  ? 565 GLU E CG  1 
ATOM   14172 C CD  . GLU E 1 363 ? 49.281  -23.167 54.917 1.00 64.12  ? 565 GLU E CD  1 
ATOM   14173 O OE1 . GLU E 1 363 ? 49.607  -21.974 55.071 1.00 64.29  ? 565 GLU E OE1 1 
ATOM   14174 O OE2 . GLU E 1 363 ? 50.110  -24.065 54.674 1.00 66.98  ? 565 GLU E OE2 1 
ATOM   14175 N N   . ILE E 1 364 ? 45.848  -20.385 52.375 1.00 50.54  ? 566 ILE E N   1 
ATOM   14176 C CA  . ILE E 1 364 ? 44.899  -19.316 52.099 1.00 45.67  ? 566 ILE E CA  1 
ATOM   14177 C C   . ILE E 1 364 ? 44.235  -19.321 50.718 1.00 44.37  ? 566 ILE E C   1 
ATOM   14178 O O   . ILE E 1 364 ? 43.399  -18.469 50.442 1.00 43.66  ? 566 ILE E O   1 
ATOM   14179 C CB  . ILE E 1 364 ? 45.505  -17.932 52.399 1.00 47.93  ? 566 ILE E CB  1 
ATOM   14180 C CG1 . ILE E 1 364 ? 46.567  -17.564 51.372 1.00 46.30  ? 566 ILE E CG1 1 
ATOM   14181 C CG2 . ILE E 1 364 ? 46.100  -17.904 53.796 1.00 47.49  ? 566 ILE E CG2 1 
ATOM   14182 C CD1 . ILE E 1 364 ? 47.322  -16.307 51.736 1.00 44.36  ? 566 ILE E CD1 1 
ATOM   14183 N N   . LYS E 1 365 ? 44.590  -20.269 49.857 1.00 44.58  ? 567 LYS E N   1 
ATOM   14184 C CA  . LYS E 1 365 ? 44.013  -20.328 48.509 1.00 43.75  ? 567 LYS E CA  1 
ATOM   14185 C C   . LYS E 1 365 ? 42.492  -20.505 48.494 1.00 42.77  ? 567 LYS E C   1 
ATOM   14186 O O   . LYS E 1 365 ? 41.823  -20.024 47.591 1.00 42.65  ? 567 LYS E O   1 
ATOM   14187 C CB  . LYS E 1 365 ? 44.701  -21.377 47.635 1.00 47.10  ? 567 LYS E CB  1 
ATOM   14188 C CG  . LYS E 1 365 ? 44.430  -22.817 48.014 1.00 49.98  ? 567 LYS E CG  1 
ATOM   14189 C CD  . LYS E 1 365 ? 45.153  -23.747 47.059 1.00 54.65  ? 567 LYS E CD  1 
ATOM   14190 C CE  . LYS E 1 365 ? 45.319  -25.131 47.657 1.00 56.14  ? 567 LYS E CE  1 
ATOM   14191 N NZ  . LYS E 1 365 ? 46.309  -25.115 48.765 1.00 58.60  ? 567 LYS E NZ  1 
ATOM   14192 N N   . THR E 1 366 ? 41.964  -21.260 49.447 1.00 42.85  ? 568 THR E N   1 
ATOM   14193 C CA  . THR E 1 366 ? 40.525  -21.467 49.580 1.00 41.22  ? 568 THR E CA  1 
ATOM   14194 C C   . THR E 1 366 ? 39.689  -20.175 49.456 1.00 40.94  ? 568 THR E C   1 
ATOM   14195 O O   . THR E 1 366 ? 38.621  -20.194 48.862 1.00 40.52  ? 568 THR E O   1 
ATOM   14196 C CB  . THR E 1 366 ? 40.213  -22.187 50.898 1.00 41.34  ? 568 THR E CB  1 
ATOM   14197 O OG1 . THR E 1 366 ? 41.133  -21.749 51.903 1.00 43.96  ? 568 THR E OG1 1 
ATOM   14198 C CG2 . THR E 1 366 ? 40.383  -23.673 50.724 1.00 40.49  ? 568 THR E CG2 1 
ATOM   14199 N N   . THR E 1 367 ? 40.159  -19.071 50.034 1.00 38.72  ? 569 THR E N   1 
ATOM   14200 C CA  . THR E 1 367 ? 39.492  -17.781 49.929 1.00 38.49  ? 569 THR E CA  1 
ATOM   14201 C C   . THR E 1 367 ? 40.312  -16.713 49.214 1.00 37.88  ? 569 THR E C   1 
ATOM   14202 O O   . THR E 1 367 ? 39.759  -15.668 48.860 1.00 37.98  ? 569 THR E O   1 
ATOM   14203 C CB  . THR E 1 367 ? 39.115  -17.277 51.325 1.00 38.90  ? 569 THR E CB  1 
ATOM   14204 O OG1 . THR E 1 367 ? 40.295  -17.186 52.132 1.00 40.35  ? 569 THR E OG1 1 
ATOM   14205 C CG2 . THR E 1 367 ? 38.130  -18.221 51.987 1.00 38.95  ? 569 THR E CG2 1 
ATOM   14206 N N   . ASN E 1 368 ? 41.605  -16.937 48.996 1.00 38.21  ? 570 ASN E N   1 
ATOM   14207 C CA  . ASN E 1 368 ? 42.496  -15.916 48.462 1.00 38.17  ? 570 ASN E CA  1 
ATOM   14208 C C   . ASN E 1 368 ? 42.957  -16.258 47.052 1.00 39.13  ? 570 ASN E C   1 
ATOM   14209 O O   . ASN E 1 368 ? 43.424  -17.381 46.814 1.00 40.56  ? 570 ASN E O   1 
ATOM   14210 C CB  . ASN E 1 368 ? 43.708  -15.719 49.374 1.00 38.52  ? 570 ASN E CB  1 
ATOM   14211 C CG  . ASN E 1 368 ? 43.344  -15.039 50.668 1.00 39.23  ? 570 ASN E CG  1 
ATOM   14212 O OD1 . ASN E 1 368 ? 42.323  -14.371 50.751 1.00 39.82  ? 570 ASN E OD1 1 
ATOM   14213 N ND2 . ASN E 1 368 ? 44.175  -15.198 51.681 1.00 39.94  ? 570 ASN E ND2 1 
ATOM   14214 N N   . PRO E 1 369 ? 42.832  -15.340 46.096 1.00 39.50  ? 571 PRO E N   1 
ATOM   14215 C CA  . PRO E 1 369 ? 43.399  -15.587 44.766 1.00 39.60  ? 571 PRO E CA  1 
ATOM   14216 C C   . PRO E 1 369 ? 44.911  -15.740 44.826 1.00 39.95  ? 571 PRO E C   1 
ATOM   14217 O O   . PRO E 1 369 ? 45.562  -15.308 45.780 1.00 40.06  ? 571 PRO E O   1 
ATOM   14218 C CB  . PRO E 1 369 ? 42.994  -14.340 43.974 1.00 35.96  ? 571 PRO E CB  1 
ATOM   14219 C CG  . PRO E 1 369 ? 42.844  -13.283 45.007 1.00 35.91  ? 571 PRO E CG  1 
ATOM   14220 C CD  . PRO E 1 369 ? 42.298  -13.975 46.220 1.00 35.55  ? 571 PRO E CD  1 
ATOM   14221 N N   . VAL E 1 370 ? 45.468  -16.364 43.788 1.00 43.10  ? 572 VAL E N   1 
ATOM   14222 C CA  . VAL E 1 370 ? 46.903  -16.618 43.744 1.00 42.48  ? 572 VAL E CA  1 
ATOM   14223 C C   . VAL E 1 370 ? 47.633  -15.319 43.433 1.00 42.90  ? 572 VAL E C   1 
ATOM   14224 O O   . VAL E 1 370 ? 47.167  -14.504 42.627 1.00 42.69  ? 572 VAL E O   1 
ATOM   14225 C CB  . VAL E 1 370 ? 47.220  -17.712 42.720 1.00 43.57  ? 572 VAL E CB  1 
ATOM   14226 C CG1 . VAL E 1 370 ? 48.718  -17.898 42.577 1.00 43.27  ? 572 VAL E CG1 1 
ATOM   14227 C CG2 . VAL E 1 370 ? 46.571  -19.013 43.139 1.00 43.16  ? 572 VAL E CG2 1 
ATOM   14228 N N   . ALA E 1 371 ? 48.784  -15.119 44.077 1.00 43.60  ? 573 ALA E N   1 
ATOM   14229 C CA  . ALA E 1 371 ? 49.576  -13.906 43.912 1.00 43.67  ? 573 ALA E CA  1 
ATOM   14230 C C   . ALA E 1 371 ? 50.037  -13.714 42.474 1.00 44.27  ? 573 ALA E C   1 
ATOM   14231 O O   . ALA E 1 371 ? 50.067  -12.587 41.975 1.00 43.63  ? 573 ALA E O   1 
ATOM   14232 C CB  . ALA E 1 371 ? 50.787  -13.930 44.844 1.00 43.73  ? 573 ALA E CB  1 
ATOM   14233 N N   . THR E 1 372 ? 50.398  -14.800 41.800 1.00 42.86  ? 574 THR E N   1 
ATOM   14234 C CA  . THR E 1 372 ? 50.952  -14.727 40.457 1.00 43.35  ? 574 THR E CA  1 
ATOM   14235 C C   . THR E 1 372 ? 49.891  -14.816 39.368 1.00 44.24  ? 574 THR E C   1 
ATOM   14236 O O   . THR E 1 372 ? 50.240  -14.851 38.186 1.00 45.44  ? 574 THR E O   1 
ATOM   14237 C CB  . THR E 1 372 ? 51.993  -15.828 40.259 1.00 49.45  ? 574 THR E CB  1 
ATOM   14238 O OG1 . THR E 1 372 ? 51.377  -17.109 40.432 1.00 49.46  ? 574 THR E OG1 1 
ATOM   14239 C CG2 . THR E 1 372 ? 53.109  -15.679 41.274 1.00 48.92  ? 574 THR E CG2 1 
ATOM   14240 N N   . GLU E 1 373 ? 48.615  -14.857 39.735 1.00 40.55  ? 575 GLU E N   1 
ATOM   14241 C CA  . GLU E 1 373 ? 47.522  -14.964 38.782 1.00 42.08  ? 575 GLU E CA  1 
ATOM   14242 C C   . GLU E 1 373 ? 46.657  -13.713 38.844 1.00 40.64  ? 575 GLU E C   1 
ATOM   14243 O O   . GLU E 1 373 ? 46.608  -13.016 39.861 1.00 40.34  ? 575 GLU E O   1 
ATOM   14244 C CB  . GLU E 1 373 ? 46.654  -16.198 39.062 1.00 39.93  ? 575 GLU E CB  1 
ATOM   14245 C CG  . GLU E 1 373 ? 47.366  -17.528 38.915 1.00 46.93  ? 575 GLU E CG  1 
ATOM   14246 C CD  . GLU E 1 373 ? 47.927  -17.745 37.527 1.00 51.28  ? 575 GLU E CD  1 
ATOM   14247 O OE1 . GLU E 1 373 ? 47.263  -17.351 36.545 1.00 53.82  ? 575 GLU E OE1 1 
ATOM   14248 O OE2 . GLU E 1 373 ? 49.030  -18.318 37.417 1.00 53.93  ? 575 GLU E OE2 1 
ATOM   14249 N N   . SER E 1 374 ? 45.969  -13.436 37.738 1.00 34.98  ? 576 SER E N   1 
ATOM   14250 C CA  . SER E 1 374 ? 45.043  -12.313 37.700 1.00 34.88  ? 576 SER E CA  1 
ATOM   14251 C C   . SER E 1 374 ? 43.849  -12.574 38.607 1.00 34.24  ? 576 SER E C   1 
ATOM   14252 O O   . SER E 1 374 ? 43.535  -13.720 38.936 1.00 35.06  ? 576 SER E O   1 
ATOM   14253 C CB  . SER E 1 374 ? 44.558  -12.066 36.273 1.00 33.38  ? 576 SER E CB  1 
ATOM   14254 O OG  . SER E 1 374 ? 45.610  -11.630 35.438 1.00 36.78  ? 576 SER E OG  1 
ATOM   14255 N N   . TYR E 1 375 ? 43.178  -11.495 39.010 1.00 27.29  ? 577 TYR E N   1 
ATOM   14256 C CA  . TYR E 1 375 ? 41.974  -11.647 39.817 1.00 26.04  ? 577 TYR E CA  1 
ATOM   14257 C C   . TYR E 1 375 ? 40.844  -12.245 38.995 1.00 26.45  ? 577 TYR E C   1 
ATOM   14258 O O   . TYR E 1 375 ? 40.048  -13.042 39.504 1.00 26.10  ? 577 TYR E O   1 
ATOM   14259 C CB  . TYR E 1 375 ? 41.549  -10.300 40.396 1.00 27.28  ? 577 TYR E CB  1 
ATOM   14260 C CG  . TYR E 1 375 ? 40.296  -10.376 41.237 1.00 26.48  ? 577 TYR E CG  1 
ATOM   14261 C CD1 . TYR E 1 375 ? 40.354  -10.795 42.556 1.00 26.55  ? 577 TYR E CD1 1 
ATOM   14262 C CD2 . TYR E 1 375 ? 39.057  -10.057 40.706 1.00 25.51  ? 577 TYR E CD2 1 
ATOM   14263 C CE1 . TYR E 1 375 ? 39.218  -10.874 43.325 1.00 26.44  ? 577 TYR E CE1 1 
ATOM   14264 C CE2 . TYR E 1 375 ? 37.916  -10.137 41.468 1.00 24.95  ? 577 TYR E CE2 1 
ATOM   14265 C CZ  . TYR E 1 375 ? 38.002  -10.545 42.776 1.00 25.50  ? 577 TYR E CZ  1 
ATOM   14266 O OH  . TYR E 1 375 ? 36.867  -10.625 43.544 1.00 25.76  ? 577 TYR E OH  1 
ATOM   14267 N N   . GLY E 1 376 ? 40.761  -11.879 37.727 1.00 24.63  ? 578 GLY E N   1 
ATOM   14268 C CA  . GLY E 1 376 ? 39.675  -12.341 36.898 1.00 24.25  ? 578 GLY E CA  1 
ATOM   14269 C C   . GLY E 1 376 ? 39.649  -11.607 35.582 1.00 24.74  ? 578 GLY E C   1 
ATOM   14270 O O   . GLY E 1 376 ? 40.664  -11.077 35.130 1.00 24.53  ? 578 GLY E O   1 
ATOM   14271 N N   . GLN E 1 377 ? 38.470  -11.585 34.968 1.00 23.27  ? 579 GLN E N   1 
ATOM   14272 C CA  . GLN E 1 377 ? 38.276  -10.905 33.696 1.00 24.37  ? 579 GLN E CA  1 
ATOM   14273 C C   . GLN E 1 377 ? 37.112  -9.938  33.811 1.00 23.48  ? 579 GLN E C   1 
ATOM   14274 O O   . GLN E 1 377 ? 36.221  -10.128 34.642 1.00 23.40  ? 579 GLN E O   1 
ATOM   14275 C CB  . GLN E 1 377 ? 38.023  -11.901 32.565 1.00 22.69  ? 579 GLN E CB  1 
ATOM   14276 C CG  . GLN E 1 377 ? 39.205  -12.788 32.262 1.00 29.02  ? 579 GLN E CG  1 
ATOM   14277 C CD  . GLN E 1 377 ? 38.912  -13.771 31.156 1.00 34.31  ? 579 GLN E CD  1 
ATOM   14278 O OE1 . GLN E 1 377 ? 37.757  -14.113 30.906 1.00 37.50  ? 579 GLN E OE1 1 
ATOM   14279 N NE2 . GLN E 1 377 ? 39.955  -14.223 30.476 1.00 35.77  ? 579 GLN E NE2 1 
ATOM   14280 N N   . VAL E 1 378 ? 37.130  -8.904  32.978 1.00 22.22  ? 580 VAL E N   1 
ATOM   14281 C CA  . VAL E 1 378 ? 36.115  -7.860  32.959 1.00 22.12  ? 580 VAL E CA  1 
ATOM   14282 C C   . VAL E 1 378 ? 35.816  -7.521  31.508 1.00 22.87  ? 580 VAL E C   1 
ATOM   14283 O O   . VAL E 1 378 ? 36.732  -7.467  30.681 1.00 22.60  ? 580 VAL E O   1 
ATOM   14284 C CB  . VAL E 1 378 ? 36.576  -6.608  33.729 1.00 22.14  ? 580 VAL E CB  1 
ATOM   14285 C CG1 . VAL E 1 378 ? 35.642  -5.467  33.485 1.00 22.57  ? 580 VAL E CG1 1 
ATOM   14286 C CG2 . VAL E 1 378 ? 36.602  -6.886  35.201 1.00 21.08  ? 580 VAL E CG2 1 
ATOM   14287 N N   . ALA E 1 379 ? 34.539  -7.309  31.198 1.00 19.75  ? 581 ALA E N   1 
ATOM   14288 C CA  . ALA E 1 379 ? 34.141  -6.862  29.870 1.00 21.19  ? 581 ALA E CA  1 
ATOM   14289 C C   . ALA E 1 379 ? 34.774  -5.508  29.585 1.00 22.20  ? 581 ALA E C   1 
ATOM   14290 O O   . ALA E 1 379 ? 34.654  -4.581  30.389 1.00 21.84  ? 581 ALA E O   1 
ATOM   14291 C CB  . ALA E 1 379 ? 32.622  -6.775  29.769 1.00 21.44  ? 581 ALA E CB  1 
ATOM   14292 N N   . THR E 1 380 ? 35.472  -5.398  28.455 1.00 22.25  ? 582 THR E N   1 
ATOM   14293 C CA  . THR E 1 380 ? 36.144  -4.144  28.134 1.00 22.91  ? 582 THR E CA  1 
ATOM   14294 C C   . THR E 1 380 ? 35.343  -3.299  27.149 1.00 24.17  ? 582 THR E C   1 
ATOM   14295 O O   . THR E 1 380 ? 35.778  -2.204  26.776 1.00 24.81  ? 582 THR E O   1 
ATOM   14296 C CB  . THR E 1 380 ? 37.545  -4.421  27.594 1.00 28.67  ? 582 THR E CB  1 
ATOM   14297 O OG1 . THR E 1 380 ? 37.467  -5.320  26.481 1.00 30.33  ? 582 THR E OG1 1 
ATOM   14298 C CG2 . THR E 1 380 ? 38.419  -5.020  28.678 1.00 26.51  ? 582 THR E CG2 1 
ATOM   14299 N N   . ASN E 1 381 ? 34.185  -3.778  26.709 1.00 23.35  ? 583 ASN E N   1 
ATOM   14300 C CA  . ASN E 1 381 ? 33.389  -3.049  25.732 1.00 24.23  ? 583 ASN E CA  1 
ATOM   14301 C C   . ASN E 1 381 ? 31.942  -3.526  25.733 1.00 25.50  ? 583 ASN E C   1 
ATOM   14302 O O   . ASN E 1 381 ? 31.532  -4.364  26.539 1.00 25.74  ? 583 ASN E O   1 
ATOM   14303 C CB  . ASN E 1 381 ? 33.984  -3.202  24.327 1.00 26.61  ? 583 ASN E CB  1 
ATOM   14304 C CG  . ASN E 1 381 ? 33.930  -4.628  23.821 1.00 26.89  ? 583 ASN E CG  1 
ATOM   14305 O OD1 . ASN E 1 381 ? 33.711  -5.564  24.583 1.00 28.33  ? 583 ASN E OD1 1 
ATOM   14306 N ND2 . ASN E 1 381 ? 34.122  -4.797  22.521 1.00 27.12  ? 583 ASN E ND2 1 
ATOM   14307 N N   . HIS E 1 382 ? 31.166  -2.955  24.815 1.00 25.67  ? 584 HIS E N   1 
ATOM   14308 C CA  . HIS E 1 382 ? 29.835  -3.445  24.493 1.00 26.31  ? 584 HIS E CA  1 
ATOM   14309 C C   . HIS E 1 382 ? 29.881  -4.243  23.201 1.00 25.95  ? 584 HIS E C   1 
ATOM   14310 O O   . HIS E 1 382 ? 30.440  -3.793  22.198 1.00 26.15  ? 584 HIS E O   1 
ATOM   14311 C CB  . HIS E 1 382 ? 28.841  -2.297  24.332 1.00 18.96  ? 584 HIS E CB  1 
ATOM   14312 C CG  . HIS E 1 382 ? 28.557  -1.556  25.597 1.00 22.32  ? 584 HIS E CG  1 
ATOM   14313 N ND1 . HIS E 1 382 ? 27.974  -0.309  25.610 1.00 23.86  ? 584 HIS E ND1 1 
ATOM   14314 C CD2 . HIS E 1 382 ? 28.746  -1.897  26.893 1.00 24.54  ? 584 HIS E CD2 1 
ATOM   14315 C CE1 . HIS E 1 382 ? 27.835  0.095   26.859 1.00 25.09  ? 584 HIS E CE1 1 
ATOM   14316 N NE2 . HIS E 1 382 ? 28.295  -0.850  27.657 1.00 26.46  ? 584 HIS E NE2 1 
ATOM   14317 N N   . GLN E 1 383 ? 29.298  -5.432  23.233 1.00 30.15  ? 585 GLN E N   1 
ATOM   14318 C CA  . GLN E 1 383 ? 29.117  -6.200  22.016 1.00 29.31  ? 585 GLN E CA  1 
ATOM   14319 C C   . GLN E 1 383 ? 28.006  -5.586  21.177 1.00 29.59  ? 585 GLN E C   1 
ATOM   14320 O O   . GLN E 1 383 ? 27.171  -4.828  21.678 1.00 29.37  ? 585 GLN E O   1 
ATOM   14321 C CB  . GLN E 1 383 ? 28.753  -7.642  22.331 1.00 29.27  ? 585 GLN E CB  1 
ATOM   14322 C CG  . GLN E 1 383 ? 27.378  -7.741  22.923 1.00 27.49  ? 585 GLN E CG  1 
ATOM   14323 C CD  . GLN E 1 383 ? 26.942  -9.153  23.114 1.00 26.33  ? 585 GLN E CD  1 
ATOM   14324 O OE1 . GLN E 1 383 ? 27.765  -10.063 23.164 1.00 26.10  ? 585 GLN E OE1 1 
ATOM   14325 N NE2 . GLN E 1 383 ? 25.638  -9.357  23.207 1.00 25.74  ? 585 GLN E NE2 1 
ATOM   14326 N N   . SER E 1 384 ? 28.002  -5.922  19.897 1.00 28.68  ? 586 SER E N   1 
ATOM   14327 C CA  . SER E 1 384 ? 26.953  -5.515  18.977 1.00 29.28  ? 586 SER E CA  1 
ATOM   14328 C C   . SER E 1 384 ? 27.021  -6.460  17.792 1.00 29.77  ? 586 SER E C   1 
ATOM   14329 O O   . SER E 1 384 ? 27.851  -7.368  17.755 1.00 29.15  ? 586 SER E O   1 
ATOM   14330 C CB  . SER E 1 384 ? 27.116  -4.056  18.546 1.00 34.10  ? 586 SER E CB  1 
ATOM   14331 O OG  . SER E 1 384 ? 26.953  -3.173  19.642 1.00 33.57  ? 586 SER E OG  1 
ATOM   14332 N N   . ALA E 1 385 ? 26.147  -6.241  16.813 1.00 30.67  ? 587 ALA E N   1 
ATOM   14333 C CA  . ALA E 1 385 ? 26.244  -7.006  15.577 1.00 31.85  ? 587 ALA E CA  1 
ATOM   14334 C C   . ALA E 1 385 ? 27.623  -6.840  14.950 1.00 33.29  ? 587 ALA E C   1 
ATOM   14335 O O   . ALA E 1 385 ? 28.178  -7.782  14.376 1.00 33.37  ? 587 ALA E O   1 
ATOM   14336 C CB  . ALA E 1 385 ? 25.146  -6.574  14.608 1.00 29.76  ? 587 ALA E CB  1 
ATOM   14337 N N   . GLN E 1 386 ? 28.198  -5.641  15.068 1.00 34.57  ? 588 GLN E N   1 
ATOM   14338 C CA  . GLN E 1 386 ? 29.509  -5.378  14.483 1.00 36.67  ? 588 GLN E CA  1 
ATOM   14339 C C   . GLN E 1 386 ? 30.645  -5.856  15.381 1.00 36.66  ? 588 GLN E C   1 
ATOM   14340 O O   . GLN E 1 386 ? 31.626  -6.427  14.892 1.00 37.83  ? 588 GLN E O   1 
ATOM   14341 C CB  . GLN E 1 386 ? 29.654  -3.888  14.184 1.00 39.48  ? 588 GLN E CB  1 
ATOM   14342 C CG  . GLN E 1 386 ? 28.699  -3.373  13.115 1.00 39.48  ? 588 GLN E CG  1 
ATOM   14343 C CD  . GLN E 1 386 ? 27.323  -3.050  13.664 1.00 39.48  ? 588 GLN E CD  1 
ATOM   14344 O OE1 . GLN E 1 386 ? 27.068  -3.198  14.859 1.00 39.48  ? 588 GLN E OE1 1 
ATOM   14345 N NE2 . GLN E 1 386 ? 26.427  -2.612  12.791 1.00 39.48  ? 588 GLN E NE2 1 
ATOM   14346 N N   . ALA E 1 387 ? 30.538  -5.636  16.690 1.00 32.56  ? 589 ALA E N   1 
ATOM   14347 C CA  . ALA E 1 387 ? 31.645  -5.843  17.616 1.00 30.71  ? 589 ALA E CA  1 
ATOM   14348 C C   . ALA E 1 387 ? 31.422  -7.091  18.459 1.00 29.68  ? 589 ALA E C   1 
ATOM   14349 O O   . ALA E 1 387 ? 30.383  -7.226  19.111 1.00 30.09  ? 589 ALA E O   1 
ATOM   14350 C CB  . ALA E 1 387 ? 31.824  -4.630  18.528 1.00 30.98  ? 589 ALA E CB  1 
ATOM   14351 N N   . GLN E 1 388 ? 32.397  -7.995  18.445 1.00 31.47  ? 590 GLN E N   1 
ATOM   14352 C CA  . GLN E 1 388 ? 32.351  -9.161  19.316 1.00 31.40  ? 590 GLN E CA  1 
ATOM   14353 C C   . GLN E 1 388 ? 32.842  -8.822  20.718 1.00 30.32  ? 590 GLN E C   1 
ATOM   14354 O O   . GLN E 1 388 ? 33.623  -7.891  20.922 1.00 29.78  ? 590 GLN E O   1 
ATOM   14355 C CB  . GLN E 1 388 ? 33.164  -10.307 18.717 1.00 33.88  ? 590 GLN E CB  1 
ATOM   14356 C CG  . GLN E 1 388 ? 34.624  -10.021 18.501 1.00 33.88  ? 590 GLN E CG  1 
ATOM   14357 C CD  . GLN E 1 388 ? 35.335  -11.195 17.863 1.00 33.88  ? 590 GLN E CD  1 
ATOM   14358 O OE1 . GLN E 1 388 ? 34.701  -12.077 17.287 1.00 33.88  ? 590 GLN E OE1 1 
ATOM   14359 N NE2 . GLN E 1 388 ? 36.658  -11.210 17.958 1.00 33.88  ? 590 GLN E NE2 1 
ATOM   14360 N N   . ALA E 1 389 ? 32.361  -9.594  21.690 1.00 29.46  ? 591 ALA E N   1 
ATOM   14361 C CA  . ALA E 1 389 ? 32.648  -9.318  23.090 1.00 29.22  ? 591 ALA E CA  1 
ATOM   14362 C C   . ALA E 1 389 ? 34.138  -9.434  23.376 1.00 29.04  ? 591 ALA E C   1 
ATOM   14363 O O   . ALA E 1 389 ? 34.790  -10.406 22.986 1.00 28.69  ? 591 ALA E O   1 
ATOM   14364 C CB  . ALA E 1 389 ? 31.871  -10.281 23.986 1.00 26.11  ? 591 ALA E CB  1 
ATOM   14365 N N   . GLN E 1 390 ? 34.675  -8.436  24.072 1.00 25.83  ? 592 GLN E N   1 
ATOM   14366 C CA  . GLN E 1 390 ? 36.070  -8.429  24.483 1.00 26.33  ? 592 GLN E CA  1 
ATOM   14367 C C   . GLN E 1 390 ? 36.153  -8.373  25.999 1.00 26.13  ? 592 GLN E C   1 
ATOM   14368 O O   . GLN E 1 390 ? 35.287  -7.785  26.654 1.00 25.55  ? 592 GLN E O   1 
ATOM   14369 C CB  . GLN E 1 390 ? 36.826  -7.250  23.872 1.00 29.84  ? 592 GLN E CB  1 
ATOM   14370 C CG  . GLN E 1 390 ? 36.983  -7.342  22.374 1.00 29.84  ? 592 GLN E CG  1 
ATOM   14371 C CD  . GLN E 1 390 ? 37.720  -6.157  21.799 1.00 29.84  ? 592 GLN E CD  1 
ATOM   14372 O OE1 . GLN E 1 390 ? 37.745  -5.080  22.392 1.00 29.84  ? 592 GLN E OE1 1 
ATOM   14373 N NE2 . GLN E 1 390 ? 38.330  -6.349  20.638 1.00 29.84  ? 592 GLN E NE2 1 
ATOM   14374 N N   . THR E 1 391 ? 37.195  -8.983  26.546 1.00 26.11  ? 593 THR E N   1 
ATOM   14375 C CA  . THR E 1 391 ? 37.473  -8.989  27.971 1.00 26.39  ? 593 THR E CA  1 
ATOM   14376 C C   . THR E 1 391 ? 38.903  -8.523  28.200 1.00 24.86  ? 593 THR E C   1 
ATOM   14377 O O   . THR E 1 391 ? 39.701  -8.404  27.269 1.00 24.97  ? 593 THR E O   1 
ATOM   14378 C CB  . THR E 1 391 ? 37.270  -10.382 28.584 1.00 27.14  ? 593 THR E CB  1 
ATOM   14379 O OG1 . THR E 1 391 ? 38.127  -11.325 27.931 1.00 29.58  ? 593 THR E OG1 1 
ATOM   14380 C CG2 . THR E 1 391 ? 35.826  -10.832 28.443 1.00 26.64  ? 593 THR E CG2 1 
ATOM   14381 N N   . GLY E 1 392 ? 39.225  -8.256  29.459 1.00 24.63  ? 594 GLY E N   1 
ATOM   14382 C CA  . GLY E 1 392 ? 40.594  -7.937  29.793 1.00 22.71  ? 594 GLY E CA  1 
ATOM   14383 C C   . GLY E 1 392 ? 40.973  -8.415  31.174 1.00 21.67  ? 594 GLY E C   1 
ATOM   14384 O O   . GLY E 1 392 ? 40.118  -8.574  32.048 1.00 21.76  ? 594 GLY E O   1 
ATOM   14385 N N   . TRP E 1 393 ? 42.266  -8.627  31.386 1.00 28.34  ? 595 TRP E N   1 
ATOM   14386 C CA  . TRP E 1 393 ? 42.724  -9.225  32.628 1.00 27.66  ? 595 TRP E CA  1 
ATOM   14387 C C   . TRP E 1 393 ? 42.841  -8.166  33.710 1.00 25.94  ? 595 TRP E C   1 
ATOM   14388 O O   . TRP E 1 393 ? 43.466  -7.122  33.514 1.00 25.91  ? 595 TRP E O   1 
ATOM   14389 C CB  . TRP E 1 393 ? 44.073  -9.910  32.424 1.00 25.67  ? 595 TRP E CB  1 
ATOM   14390 C CG  . TRP E 1 393 ? 44.022  -11.077 31.505 1.00 29.47  ? 595 TRP E CG  1 
ATOM   14391 C CD1 . TRP E 1 393 ? 44.334  -11.089 30.182 1.00 30.16  ? 595 TRP E CD1 1 
ATOM   14392 C CD2 . TRP E 1 393 ? 43.617  -12.408 31.835 1.00 31.81  ? 595 TRP E CD2 1 
ATOM   14393 N NE1 . TRP E 1 393 ? 44.159  -12.347 29.665 1.00 31.63  ? 595 TRP E NE1 1 
ATOM   14394 C CE2 . TRP E 1 393 ? 43.716  -13.176 30.661 1.00 32.15  ? 595 TRP E CE2 1 
ATOM   14395 C CE3 . TRP E 1 393 ? 43.184  -13.025 33.010 1.00 33.81  ? 595 TRP E CE3 1 
ATOM   14396 C CZ2 . TRP E 1 393 ? 43.401  -14.531 30.629 1.00 32.92  ? 595 TRP E CZ2 1 
ATOM   14397 C CZ3 . TRP E 1 393 ? 42.870  -14.368 32.975 1.00 35.24  ? 595 TRP E CZ3 1 
ATOM   14398 C CH2 . TRP E 1 393 ? 42.980  -15.107 31.794 1.00 34.56  ? 595 TRP E CH2 1 
ATOM   14399 N N   . VAL E 1 394 ? 42.243  -8.441  34.861 1.00 29.77  ? 596 VAL E N   1 
ATOM   14400 C CA  . VAL E 1 394 ? 42.357  -7.572  36.021 1.00 28.14  ? 596 VAL E CA  1 
ATOM   14401 C C   . VAL E 1 394 ? 43.637  -7.983  36.731 1.00 28.30  ? 596 VAL E C   1 
ATOM   14402 O O   . VAL E 1 394 ? 43.742  -9.094  37.254 1.00 27.78  ? 596 VAL E O   1 
ATOM   14403 C CB  . VAL E 1 394 ? 41.143  -7.688  36.942 1.00 25.78  ? 596 VAL E CB  1 
ATOM   14404 C CG1 . VAL E 1 394 ? 41.376  -6.895  38.202 1.00 24.33  ? 596 VAL E CG1 1 
ATOM   14405 C CG2 . VAL E 1 394 ? 39.907  -7.214  36.229 1.00 23.71  ? 596 VAL E CG2 1 
ATOM   14406 N N   . GLN E 1 395 ? 44.617  -7.082  36.751 1.00 31.80  ? 597 GLN E N   1 
ATOM   14407 C CA  . GLN E 1 395 ? 45.875  -7.399  37.410 1.00 32.54  ? 597 GLN E CA  1 
ATOM   14408 C C   . GLN E 1 395 ? 45.781  -7.155  38.908 1.00 32.87  ? 597 GLN E C   1 
ATOM   14409 O O   . GLN E 1 395 ? 46.337  -7.918  39.705 1.00 33.79  ? 597 GLN E O   1 
ATOM   14410 C CB  . GLN E 1 395 ? 47.006  -6.586  36.789 1.00 33.32  ? 597 GLN E CB  1 
ATOM   14411 C CG  . GLN E 1 395 ? 47.203  -6.851  35.305 1.00 34.67  ? 597 GLN E CG  1 
ATOM   14412 C CD  . GLN E 1 395 ? 47.408  -8.316  34.990 1.00 33.49  ? 597 GLN E CD  1 
ATOM   14413 O OE1 . GLN E 1 395 ? 48.004  -9.053  35.770 1.00 34.92  ? 597 GLN E OE1 1 
ATOM   14414 N NE2 . GLN E 1 395 ? 46.944  -8.739  33.823 1.00 33.04  ? 597 GLN E NE2 1 
ATOM   14415 N N   . ASN E 1 396 ? 45.077  -6.102  39.307 1.00 30.77  ? 598 ASN E N   1 
ATOM   14416 C CA  . ASN E 1 396 ? 44.848  -5.791  40.707 1.00 30.60  ? 598 ASN E CA  1 
ATOM   14417 C C   . ASN E 1 396 ? 43.404  -5.356  40.912 1.00 30.22  ? 598 ASN E C   1 
ATOM   14418 O O   . ASN E 1 396 ? 42.810  -4.704  40.048 1.00 31.42  ? 598 ASN E O   1 
ATOM   14419 C CB  . ASN E 1 396 ? 45.807  -4.704  41.200 1.00 32.72  ? 598 ASN E CB  1 
ATOM   14420 C CG  . ASN E 1 396 ? 45.661  -3.407  40.440 1.00 33.69  ? 598 ASN E CG  1 
ATOM   14421 O OD1 . ASN E 1 396 ? 45.098  -3.368  39.349 1.00 34.49  ? 598 ASN E OD1 1 
ATOM   14422 N ND2 . ASN E 1 396 ? 46.164  -2.332  41.020 1.00 33.26  ? 598 ASN E ND2 1 
ATOM   14423 N N   . GLN E 1 397 ? 42.843  -5.724  42.061 1.00 29.27  ? 599 GLN E N   1 
ATOM   14424 C CA  . GLN E 1 397 ? 41.451  -5.440  42.379 1.00 27.35  ? 599 GLN E CA  1 
ATOM   14425 C C   . GLN E 1 397 ? 41.359  -4.938  43.808 1.00 27.30  ? 599 GLN E C   1 
ATOM   14426 O O   . GLN E 1 397 ? 41.758  -5.642  44.738 1.00 27.84  ? 599 GLN E O   1 
ATOM   14427 C CB  . GLN E 1 397 ? 40.580  -6.685  42.196 1.00 27.11  ? 599 GLN E CB  1 
ATOM   14428 C CG  . GLN E 1 397 ? 39.108  -6.462  42.471 1.00 26.53  ? 599 GLN E CG  1 
ATOM   14429 C CD  . GLN E 1 397 ? 38.494  -5.458  41.533 1.00 26.86  ? 599 GLN E CD  1 
ATOM   14430 O OE1 . GLN E 1 397 ? 38.532  -5.628  40.319 1.00 29.00  ? 599 GLN E OE1 1 
ATOM   14431 N NE2 . GLN E 1 397 ? 37.917  -4.404  42.090 1.00 25.94  ? 599 GLN E NE2 1 
ATOM   14432 N N   . GLY E 1 398 ? 40.825  -3.732  43.983 1.00 27.49  ? 600 GLY E N   1 
ATOM   14433 C CA  . GLY E 1 398 ? 40.538  -3.221  45.302 1.00 26.07  ? 600 GLY E CA  1 
ATOM   14434 C C   . GLY E 1 398 ? 39.338  -3.908  45.920 1.00 25.88  ? 600 GLY E C   1 
ATOM   14435 O O   . GLY E 1 398 ? 38.696  -4.771  45.323 1.00 25.44  ? 600 GLY E O   1 
ATOM   14436 N N   . ILE E 1 399 ? 39.031  -3.506  47.154 1.00 25.70  ? 601 ILE E N   1 
ATOM   14437 C CA  . ILE E 1 399 ? 37.932  -4.121  47.887 1.00 24.98  ? 601 ILE E CA  1 
ATOM   14438 C C   . ILE E 1 399 ? 36.612  -3.902  47.161 1.00 24.56  ? 601 ILE E C   1 
ATOM   14439 O O   . ILE E 1 399 ? 36.360  -2.841  46.583 1.00 25.23  ? 601 ILE E O   1 
ATOM   14440 C CB  . ILE E 1 399 ? 37.889  -3.575  49.325 1.00 25.30  ? 601 ILE E CB  1 
ATOM   14441 C CG1 . ILE E 1 399 ? 39.138  -4.006  50.086 1.00 25.70  ? 601 ILE E CG1 1 
ATOM   14442 C CG2 . ILE E 1 399 ? 36.663  -4.056  50.051 1.00 26.76  ? 601 ILE E CG2 1 
ATOM   14443 C CD1 . ILE E 1 399 ? 39.280  -5.508  50.192 1.00 24.56  ? 601 ILE E CD1 1 
ATOM   14444 N N   . LEU E 1 400 ? 35.779  -4.936  47.168 1.00 25.17  ? 602 LEU E N   1 
ATOM   14445 C CA  . LEU E 1 400 ? 34.414  -4.955  46.673 1.00 24.62  ? 602 LEU E CA  1 
ATOM   14446 C C   . LEU E 1 400 ? 33.512  -5.539  47.747 1.00 25.69  ? 602 LEU E C   1 
ATOM   14447 O O   . LEU E 1 400 ? 33.938  -6.420  48.499 1.00 25.36  ? 602 LEU E O   1 
ATOM   14448 C CB  . LEU E 1 400 ? 34.293  -5.799  45.398 1.00 23.99  ? 602 LEU E CB  1 
ATOM   14449 C CG  . LEU E 1 400 ? 35.002  -5.318  44.138 1.00 23.26  ? 602 LEU E CG  1 
ATOM   14450 C CD1 . LEU E 1 400 ? 34.954  -6.391  43.078 1.00 22.73  ? 602 LEU E CD1 1 
ATOM   14451 C CD2 . LEU E 1 400 ? 34.336  -4.062  43.632 1.00 22.22  ? 602 LEU E CD2 1 
ATOM   14452 N N   . PRO E 1 401 ? 32.273  -5.065  47.855 1.00 25.79  ? 603 PRO E N   1 
ATOM   14453 C CA  . PRO E 1 401 ? 31.336  -5.693  48.790 1.00 25.98  ? 603 PRO E CA  1 
ATOM   14454 C C   . PRO E 1 401 ? 31.112  -7.149  48.417 1.00 26.19  ? 603 PRO E C   1 
ATOM   14455 O O   . PRO E 1 401 ? 30.815  -7.475  47.266 1.00 26.60  ? 603 PRO E O   1 
ATOM   14456 C CB  . PRO E 1 401 ? 30.062  -4.859  48.624 1.00 20.73  ? 603 PRO E CB  1 
ATOM   14457 C CG  . PRO E 1 401 ? 30.542  -3.550  48.136 1.00 23.21  ? 603 PRO E CG  1 
ATOM   14458 C CD  . PRO E 1 401 ? 31.700  -3.858  47.241 1.00 21.87  ? 603 PRO E CD  1 
ATOM   14459 N N   . GLY E 1 402 ? 31.254  -8.026  49.403 1.00 26.32  ? 604 GLY E N   1 
ATOM   14460 C CA  . GLY E 1 402 ? 31.148  -9.448  49.179 1.00 25.29  ? 604 GLY E CA  1 
ATOM   14461 C C   . GLY E 1 402 ? 32.453  -10.208 49.240 1.00 25.14  ? 604 GLY E C   1 
ATOM   14462 O O   . GLY E 1 402 ? 32.427  -11.443 49.209 1.00 25.38  ? 604 GLY E O   1 
ATOM   14463 N N   . MET E 1 403 ? 33.589  -9.522  49.324 1.00 28.72  ? 605 MET E N   1 
ATOM   14464 C CA  . MET E 1 403 ? 34.869  -10.206 49.419 1.00 27.40  ? 605 MET E CA  1 
ATOM   14465 C C   . MET E 1 403 ? 35.094  -10.776 50.811 1.00 26.75  ? 605 MET E C   1 
ATOM   14466 O O   . MET E 1 403 ? 34.734  -10.164 51.818 1.00 27.33  ? 605 MET E O   1 
ATOM   14467 C CB  . MET E 1 403 ? 36.023  -9.270  49.067 1.00 27.93  ? 605 MET E CB  1 
ATOM   14468 C CG  . MET E 1 403 ? 36.153  -8.947  47.599 1.00 28.68  ? 605 MET E CG  1 
ATOM   14469 S SD  . MET E 1 403 ? 37.577  -7.893  47.296 1.00 31.35  ? 605 MET E SD  1 
ATOM   14470 C CE  . MET E 1 403 ? 37.499  -7.746  45.520 1.00 31.63  ? 605 MET E CE  1 
ATOM   14471 N N   . VAL E 1 404 ? 35.691  -11.963 50.856 1.00 31.01  ? 606 VAL E N   1 
ATOM   14472 C CA  . VAL E 1 404 ? 36.211  -12.550 52.081 1.00 30.55  ? 606 VAL E CA  1 
ATOM   14473 C C   . VAL E 1 404 ? 37.630  -13.012 51.791 1.00 30.65  ? 606 VAL E C   1 
ATOM   14474 O O   . VAL E 1 404 ? 37.952  -13.406 50.666 1.00 32.88  ? 606 VAL E O   1 
ATOM   14475 C CB  . VAL E 1 404 ? 35.339  -13.716 52.597 1.00 31.20  ? 606 VAL E CB  1 
ATOM   14476 C CG1 . VAL E 1 404 ? 33.957  -13.220 52.968 1.00 34.94  ? 606 VAL E CG1 1 
ATOM   14477 C CG2 . VAL E 1 404 ? 35.243  -14.812 51.560 1.00 30.28  ? 606 VAL E CG2 1 
ATOM   14478 N N   . TRP E 1 405 ? 38.490  -12.945 52.801 1.00 33.39  ? 607 TRP E N   1 
ATOM   14479 C CA  . TRP E 1 405 ? 39.893  -13.268 52.588 1.00 33.31  ? 607 TRP E CA  1 
ATOM   14480 C C   . TRP E 1 405 ? 40.513  -13.719 53.901 1.00 34.05  ? 607 TRP E C   1 
ATOM   14481 O O   . TRP E 1 405 ? 39.956  -13.512 54.981 1.00 33.71  ? 607 TRP E O   1 
ATOM   14482 C CB  . TRP E 1 405 ? 40.661  -12.074 52.012 1.00 30.08  ? 607 TRP E CB  1 
ATOM   14483 C CG  . TRP E 1 405 ? 40.697  -10.897 52.922 1.00 30.58  ? 607 TRP E CG  1 
ATOM   14484 C CD1 . TRP E 1 405 ? 41.640  -10.625 53.864 1.00 31.50  ? 607 TRP E CD1 1 
ATOM   14485 C CD2 . TRP E 1 405 ? 39.753  -9.824  52.977 1.00 30.55  ? 607 TRP E CD2 1 
ATOM   14486 N NE1 . TRP E 1 405 ? 41.341  -9.453  54.511 1.00 31.02  ? 607 TRP E NE1 1 
ATOM   14487 C CE2 . TRP E 1 405 ? 40.185  -8.941  53.984 1.00 31.43  ? 607 TRP E CE2 1 
ATOM   14488 C CE3 . TRP E 1 405 ? 38.584  -9.524  52.276 1.00 29.87  ? 607 TRP E CE3 1 
ATOM   14489 C CZ2 . TRP E 1 405 ? 39.492  -7.781  54.305 1.00 30.95  ? 607 TRP E CZ2 1 
ATOM   14490 C CZ3 . TRP E 1 405 ? 37.896  -8.375  52.597 1.00 31.42  ? 607 TRP E CZ3 1 
ATOM   14491 C CH2 . TRP E 1 405 ? 38.352  -7.516  53.602 1.00 31.22  ? 607 TRP E CH2 1 
ATOM   14492 N N   . GLN E 1 406 ? 41.678  -14.347 53.787 1.00 36.61  ? 608 GLN E N   1 
ATOM   14493 C CA  . GLN E 1 406 ? 42.499  -14.734 54.923 1.00 37.85  ? 608 GLN E CA  1 
ATOM   14494 C C   . GLN E 1 406 ? 43.698  -13.807 55.048 1.00 38.31  ? 608 GLN E C   1 
ATOM   14495 O O   . GLN E 1 406 ? 44.246  -13.330 54.051 1.00 37.50  ? 608 GLN E O   1 
ATOM   14496 C CB  . GLN E 1 406 ? 42.979  -16.183 54.792 1.00 34.39  ? 608 GLN E CB  1 
ATOM   14497 C CG  . GLN E 1 406 ? 41.911  -17.212 55.067 1.00 40.03  ? 608 GLN E CG  1 
ATOM   14498 C CD  . GLN E 1 406 ? 41.456  -17.174 56.507 1.00 43.68  ? 608 GLN E CD  1 
ATOM   14499 O OE1 . GLN E 1 406 ? 42.268  -17.048 57.419 1.00 46.96  ? 608 GLN E OE1 1 
ATOM   14500 N NE2 . GLN E 1 406 ? 40.154  -17.264 56.719 1.00 39.96  ? 608 GLN E NE2 1 
ATOM   14501 N N   . ASP E 1 407 ? 44.098  -13.553 56.289 1.00 41.62  ? 609 ASP E N   1 
ATOM   14502 C CA  . ASP E 1 407 ? 45.290  -12.769 56.550 1.00 42.40  ? 609 ASP E CA  1 
ATOM   14503 C C   . ASP E 1 407 ? 46.524  -13.651 56.391 1.00 41.49  ? 609 ASP E C   1 
ATOM   14504 O O   . ASP E 1 407 ? 46.432  -14.856 56.147 1.00 40.04  ? 609 ASP E O   1 
ATOM   14505 C CB  . ASP E 1 407 ? 45.222  -12.156 57.945 1.00 35.68  ? 609 ASP E CB  1 
ATOM   14506 C CG  . ASP E 1 407 ? 44.133  -11.109 58.068 1.00 41.05  ? 609 ASP E CG  1 
ATOM   14507 O OD1 . ASP E 1 407 ? 43.654  -10.621 57.025 1.00 42.05  ? 609 ASP E OD1 1 
ATOM   14508 O OD2 . ASP E 1 407 ? 43.748  -10.782 59.210 1.00 43.09  ? 609 ASP E OD2 1 
ATOM   14509 N N   . ARG E 1 408 ? 47.698  -13.053 56.546 1.00 43.56  ? 610 ARG E N   1 
ATOM   14510 C CA  . ARG E 1 408 ? 48.930  -13.807 56.392 1.00 43.90  ? 610 ARG E CA  1 
ATOM   14511 C C   . ARG E 1 408 ? 49.248  -14.575 57.669 1.00 43.92  ? 610 ARG E C   1 
ATOM   14512 O O   . ARG E 1 408 ? 49.019  -14.098 58.784 1.00 43.36  ? 610 ARG E O   1 
ATOM   14513 C CB  . ARG E 1 408 ? 50.083  -12.875 56.019 1.00 42.91  ? 610 ARG E CB  1 
ATOM   14514 C CG  . ARG E 1 408 ? 51.385  -13.588 55.706 1.00 44.33  ? 610 ARG E CG  1 
ATOM   14515 C CD  . ARG E 1 408 ? 52.446  -12.605 55.260 1.00 46.46  ? 610 ARG E CD  1 
ATOM   14516 N NE  . ARG E 1 408 ? 52.061  -11.969 54.005 1.00 49.36  ? 610 ARG E NE  1 
ATOM   14517 C CZ  . ARG E 1 408 ? 52.268  -12.499 52.806 1.00 50.64  ? 610 ARG E CZ  1 
ATOM   14518 N NH1 . ARG E 1 408 ? 52.864  -13.676 52.694 1.00 51.41  ? 610 ARG E NH1 1 
ATOM   14519 N NH2 . ARG E 1 408 ? 51.882  -11.853 51.717 1.00 51.65  ? 610 ARG E NH2 1 
ATOM   14520 N N   . ASP E 1 409 ? 49.773  -15.783 57.493 1.00 46.32  ? 611 ASP E N   1 
ATOM   14521 C CA  . ASP E 1 409 ? 50.066  -16.659 58.613 1.00 46.76  ? 611 ASP E CA  1 
ATOM   14522 C C   . ASP E 1 409 ? 51.229  -16.102 59.432 1.00 46.51  ? 611 ASP E C   1 
ATOM   14523 O O   . ASP E 1 409 ? 52.061  -15.337 58.939 1.00 46.31  ? 611 ASP E O   1 
ATOM   14524 C CB  . ASP E 1 409 ? 50.389  -18.067 58.108 1.00 49.56  ? 611 ASP E CB  1 
ATOM   14525 C CG  . ASP E 1 409 ? 50.450  -19.092 59.221 1.00 51.90  ? 611 ASP E CG  1 
ATOM   14526 O OD1 . ASP E 1 409 ? 50.141  -18.740 60.377 1.00 54.45  ? 611 ASP E OD1 1 
ATOM   14527 O OD2 . ASP E 1 409 ? 50.806  -20.255 58.937 1.00 50.94  ? 611 ASP E OD2 1 
ATOM   14528 N N   . VAL E 1 410 ? 51.275  -16.493 60.702 1.00 48.79  ? 612 VAL E N   1 
ATOM   14529 C CA  . VAL E 1 410 ? 52.323  -16.057 61.614 1.00 47.41  ? 612 VAL E CA  1 
ATOM   14530 C C   . VAL E 1 410 ? 53.301  -17.206 61.787 1.00 46.24  ? 612 VAL E C   1 
ATOM   14531 O O   . VAL E 1 410 ? 52.926  -18.382 61.738 1.00 45.48  ? 612 VAL E O   1 
ATOM   14532 C CB  . VAL E 1 410 ? 51.778  -15.596 62.983 1.00 43.04  ? 612 VAL E CB  1 
ATOM   14533 C CG1 . VAL E 1 410 ? 50.814  -14.436 62.808 1.00 42.40  ? 612 VAL E CG1 1 
ATOM   14534 C CG2 . VAL E 1 410 ? 51.127  -16.748 63.727 1.00 45.85  ? 612 VAL E CG2 1 
ATOM   14535 N N   . TYR E 1 411 ? 54.567  -16.860 61.979 1.00 46.59  ? 613 TYR E N   1 
ATOM   14536 C CA  . TYR E 1 411 ? 55.635  -17.843 62.004 1.00 46.21  ? 613 TYR E CA  1 
ATOM   14537 C C   . TYR E 1 411 ? 56.395  -17.777 63.320 1.00 45.88  ? 613 TYR E C   1 
ATOM   14538 O O   . TYR E 1 411 ? 56.316  -16.798 64.065 1.00 47.24  ? 613 TYR E O   1 
ATOM   14539 C CB  . TYR E 1 411 ? 56.596  -17.635 60.831 1.00 44.45  ? 613 TYR E CB  1 
ATOM   14540 C CG  . TYR E 1 411 ? 55.945  -17.861 59.492 1.00 47.95  ? 613 TYR E CG  1 
ATOM   14541 C CD1 . TYR E 1 411 ? 55.903  -19.125 58.927 1.00 49.35  ? 613 TYR E CD1 1 
ATOM   14542 C CD2 . TYR E 1 411 ? 55.357  -16.814 58.799 1.00 49.02  ? 613 TYR E CD2 1 
ATOM   14543 C CE1 . TYR E 1 411 ? 55.304  -19.339 57.707 1.00 51.41  ? 613 TYR E CE1 1 
ATOM   14544 C CE2 . TYR E 1 411 ? 54.755  -17.018 57.578 1.00 52.52  ? 613 TYR E CE2 1 
ATOM   14545 C CZ  . TYR E 1 411 ? 54.731  -18.282 57.037 1.00 53.00  ? 613 TYR E CZ  1 
ATOM   14546 O OH  . TYR E 1 411 ? 54.131  -18.493 55.819 1.00 54.96  ? 613 TYR E OH  1 
ATOM   14547 N N   . LEU E 1 412 ? 57.129  -18.855 63.599 1.00 48.45  ? 614 LEU E N   1 
ATOM   14548 C CA  . LEU E 1 412 ? 57.957  -18.895 64.798 1.00 47.91  ? 614 LEU E CA  1 
ATOM   14549 C C   . LEU E 1 412 ? 59.047  -17.832 64.734 1.00 49.00  ? 614 LEU E C   1 
ATOM   14550 O O   . LEU E 1 412 ? 59.378  -17.208 65.749 1.00 50.29  ? 614 LEU E O   1 
ATOM   14551 C CB  . LEU E 1 412 ? 58.558  -20.291 64.961 1.00 43.38  ? 614 LEU E CB  1 
ATOM   14552 C CG  . LEU E 1 412 ? 59.207  -20.673 66.290 1.00 43.12  ? 614 LEU E CG  1 
ATOM   14553 C CD1 . LEU E 1 412 ? 58.497  -19.996 67.441 1.00 43.28  ? 614 LEU E CD1 1 
ATOM   14554 C CD2 . LEU E 1 412 ? 59.152  -22.173 66.466 1.00 41.64  ? 614 LEU E CD2 1 
ATOM   14555 N N   . GLN E 1 413 ? 59.604  -17.602 63.544 1.00 49.53  ? 615 GLN E N   1 
ATOM   14556 C CA  . GLN E 1 413 ? 60.557  -16.523 63.328 1.00 49.38  ? 615 GLN E CA  1 
ATOM   14557 C C   . GLN E 1 413 ? 59.888  -15.202 62.971 1.00 48.95  ? 615 GLN E C   1 
ATOM   14558 O O   . GLN E 1 413 ? 60.577  -14.181 62.890 1.00 49.54  ? 615 GLN E O   1 
ATOM   14559 C CB  . GLN E 1 413 ? 61.538  -16.884 62.210 1.00 46.92  ? 615 GLN E CB  1 
ATOM   14560 C CG  . GLN E 1 413 ? 62.394  -18.106 62.464 1.00 52.32  ? 615 GLN E CG  1 
ATOM   14561 C CD  . GLN E 1 413 ? 61.715  -19.388 62.034 1.00 55.21  ? 615 GLN E CD  1 
ATOM   14562 O OE1 . GLN E 1 413 ? 60.584  -19.372 61.556 1.00 53.96  ? 615 GLN E OE1 1 
ATOM   14563 N NE2 . GLN E 1 413 ? 62.410  -20.507 62.190 1.00 57.80  ? 615 GLN E NE2 1 
ATOM   14564 N N   . GLY E 1 414 ? 58.578  -15.194 62.750 1.00 45.95  ? 616 GLY E N   1 
ATOM   14565 C CA  . GLY E 1 414 ? 57.897  -14.010 62.286 1.00 44.31  ? 616 GLY E CA  1 
ATOM   14566 C C   . GLY E 1 414 ? 57.518  -13.059 63.401 1.00 43.27  ? 616 GLY E C   1 
ATOM   14567 O O   . GLY E 1 414 ? 57.545  -13.404 64.586 1.00 43.01  ? 616 GLY E O   1 
ATOM   14568 N N   . PRO E 1 415 ? 57.151  -11.836 63.034 1.00 43.72  ? 617 PRO E N   1 
ATOM   14569 C CA  . PRO E 1 415 ? 56.785  -10.838 64.043 1.00 43.91  ? 617 PRO E CA  1 
ATOM   14570 C C   . PRO E 1 415 ? 55.482  -11.187 64.742 1.00 44.28  ? 617 PRO E C   1 
ATOM   14571 O O   . PRO E 1 415 ? 54.679  -11.992 64.268 1.00 44.32  ? 617 PRO E O   1 
ATOM   14572 C CB  . PRO E 1 415 ? 56.648  -9.549  63.228 1.00 42.53  ? 617 PRO E CB  1 
ATOM   14573 C CG  . PRO E 1 415 ? 56.310  -10.016 61.856 1.00 43.25  ? 617 PRO E CG  1 
ATOM   14574 C CD  . PRO E 1 415 ? 57.069  -11.296 61.667 1.00 41.86  ? 617 PRO E CD  1 
ATOM   14575 N N   . ILE E 1 416 ? 55.283  -10.556 65.897 1.00 44.01  ? 618 ILE E N   1 
ATOM   14576 C CA  . ILE E 1 416 ? 54.092  -10.773 66.709 1.00 42.24  ? 618 ILE E CA  1 
ATOM   14577 C C   . ILE E 1 416 ? 53.117  -9.626  66.491 1.00 43.07  ? 618 ILE E C   1 
ATOM   14578 O O   . ILE E 1 416 ? 51.989  -9.836  66.037 1.00 43.54  ? 618 ILE E O   1 
ATOM   14579 C CB  . ILE E 1 416 ? 54.438  -10.919 68.201 1.00 47.35  ? 618 ILE E CB  1 
ATOM   14580 C CG1 . ILE E 1 416 ? 55.310  -12.150 68.431 1.00 46.59  ? 618 ILE E CG1 1 
ATOM   14581 C CG2 . ILE E 1 416 ? 53.170  -11.031 69.025 1.00 43.82  ? 618 ILE E CG2 1 
ATOM   14582 C CD1 . ILE E 1 416 ? 55.867  -12.234 69.829 1.00 45.15  ? 618 ILE E CD1 1 
ATOM   14583 N N   . TRP E 1 417 ? 53.531  -8.411  66.831 1.00 45.68  ? 619 TRP E N   1 
ATOM   14584 C CA  . TRP E 1 417 ? 52.667  -7.246  66.733 1.00 45.94  ? 619 TRP E CA  1 
ATOM   14585 C C   . TRP E 1 417 ? 53.285  -6.205  65.810 1.00 46.51  ? 619 TRP E C   1 
ATOM   14586 O O   . TRP E 1 417 ? 54.472  -6.249  65.481 1.00 46.05  ? 619 TRP E O   1 
ATOM   14587 C CB  . TRP E 1 417 ? 52.404  -6.615  68.107 1.00 45.50  ? 619 TRP E CB  1 
ATOM   14588 C CG  . TRP E 1 417 ? 53.634  -6.084  68.782 1.00 46.78  ? 619 TRP E CG  1 
ATOM   14589 C CD1 . TRP E 1 417 ? 54.192  -4.851  68.612 1.00 48.09  ? 619 TRP E CD1 1 
ATOM   14590 C CD2 . TRP E 1 417 ? 54.429  -6.750  69.767 1.00 46.80  ? 619 TRP E CD2 1 
ATOM   14591 N NE1 . TRP E 1 417 ? 55.299  -4.718  69.410 1.00 48.78  ? 619 TRP E NE1 1 
ATOM   14592 C CE2 . TRP E 1 417 ? 55.465  -5.870  70.133 1.00 47.88  ? 619 TRP E CE2 1 
ATOM   14593 C CE3 . TRP E 1 417 ? 54.371  -8.009  70.370 1.00 45.45  ? 619 TRP E CE3 1 
ATOM   14594 C CZ2 . TRP E 1 417 ? 56.435  -6.209  71.071 1.00 48.39  ? 619 TRP E CZ2 1 
ATOM   14595 C CZ3 . TRP E 1 417 ? 55.334  -8.343  71.300 1.00 46.92  ? 619 TRP E CZ3 1 
ATOM   14596 C CH2 . TRP E 1 417 ? 56.352  -7.448  71.642 1.00 48.46  ? 619 TRP E CH2 1 
ATOM   14597 N N   . ALA E 1 418 ? 52.445  -5.266  65.386 1.00 43.54  ? 620 ALA E N   1 
ATOM   14598 C CA  . ALA E 1 418 ? 52.884  -4.106  64.631 1.00 44.72  ? 620 ALA E CA  1 
ATOM   14599 C C   . ALA E 1 418 ? 52.034  -2.910  65.028 1.00 45.70  ? 620 ALA E C   1 
ATOM   14600 O O   . ALA E 1 418 ? 50.818  -3.016  65.202 1.00 45.56  ? 620 ALA E O   1 
ATOM   14601 C CB  . ALA E 1 418 ? 52.796  -4.341  63.121 1.00 40.77  ? 620 ALA E CB  1 
ATOM   14602 N N   . LYS E 1 419 ? 52.688  -1.763  65.172 1.00 44.77  ? 621 LYS E N   1 
ATOM   14603 C CA  . LYS E 1 419 ? 52.000  -0.533  65.532 1.00 45.35  ? 621 LYS E CA  1 
ATOM   14604 C C   . LYS E 1 419 ? 51.188  -0.032  64.346 1.00 46.21  ? 621 LYS E C   1 
ATOM   14605 O O   . LYS E 1 419 ? 51.678  -0.010  63.213 1.00 46.24  ? 621 LYS E O   1 
ATOM   14606 C CB  . LYS E 1 419 ? 52.990  0.542   65.977 1.00 46.57  ? 621 LYS E CB  1 
ATOM   14607 C CG  . LYS E 1 419 ? 52.320  1.822   66.432 1.00 47.94  ? 621 LYS E CG  1 
ATOM   14608 C CD  . LYS E 1 419 ? 53.312  2.803   67.012 1.00 49.98  ? 621 LYS E CD  1 
ATOM   14609 C CE  . LYS E 1 419 ? 52.615  4.079   67.440 1.00 52.89  ? 621 LYS E CE  1 
ATOM   14610 N NZ  . LYS E 1 419 ? 52.137  4.862   66.270 1.00 55.58  ? 621 LYS E NZ  1 
ATOM   14611 N N   . ILE E 1 420 ? 49.951  0.361   64.607 1.00 42.88  ? 622 ILE E N   1 
ATOM   14612 C CA  . ILE E 1 420 ? 49.130  0.955   63.551 1.00 43.39  ? 622 ILE E CA  1 
ATOM   14613 C C   . ILE E 1 420 ? 49.456  2.441   63.455 1.00 45.31  ? 622 ILE E C   1 
ATOM   14614 O O   . ILE E 1 420 ? 49.347  3.157   64.466 1.00 46.13  ? 622 ILE E O   1 
ATOM   14615 C CB  . ILE E 1 420 ? 47.648  0.739   63.846 1.00 45.73  ? 622 ILE E CB  1 
ATOM   14616 C CG1 . ILE E 1 420 ? 47.319  -0.752  63.862 1.00 44.56  ? 622 ILE E CG1 1 
ATOM   14617 C CG2 . ILE E 1 420 ? 46.798  1.436   62.806 1.00 45.72  ? 622 ILE E CG2 1 
ATOM   14618 C CD1 . ILE E 1 420 ? 45.962  -1.061  64.438 1.00 43.35  ? 622 ILE E CD1 1 
ATOM   14619 N N   . PRO E 1 421 ? 49.870  2.946   62.295 1.00 41.42  ? 623 PRO E N   1 
ATOM   14620 C CA  . PRO E 1 421 ? 50.156  4.379   62.181 1.00 42.35  ? 623 PRO E CA  1 
ATOM   14621 C C   . PRO E 1 421 ? 48.938  5.204   62.560 1.00 44.37  ? 623 PRO E C   1 
ATOM   14622 O O   . PRO E 1 421 ? 47.794  4.778   62.386 1.00 45.02  ? 623 PRO E O   1 
ATOM   14623 C CB  . PRO E 1 421 ? 50.511  4.552   60.700 1.00 39.01  ? 623 PRO E CB  1 
ATOM   14624 C CG  . PRO E 1 421 ? 50.994  3.219   60.278 1.00 38.97  ? 623 PRO E CG  1 
ATOM   14625 C CD  . PRO E 1 421 ? 50.159  2.234   61.041 1.00 38.48  ? 623 PRO E CD  1 
ATOM   14626 N N   . HIS E 1 422 ? 49.188  6.404   63.070 1.00 42.91  ? 624 HIS E N   1 
ATOM   14627 C CA  . HIS E 1 422 ? 48.113  7.255   63.561 1.00 44.35  ? 624 HIS E CA  1 
ATOM   14628 C C   . HIS E 1 422 ? 47.647  8.114   62.396 1.00 43.02  ? 624 HIS E C   1 
ATOM   14629 O O   . HIS E 1 422 ? 48.346  9.042   61.977 1.00 42.42  ? 624 HIS E O   1 
ATOM   14630 C CB  . HIS E 1 422 ? 48.590  8.112   64.730 1.00 39.60  ? 624 HIS E CB  1 
ATOM   14631 C CG  . HIS E 1 422 ? 47.507  8.929   65.360 1.00 44.67  ? 624 HIS E CG  1 
ATOM   14632 N ND1 . HIS E 1 422 ? 46.423  8.362   65.992 1.00 47.58  ? 624 HIS E ND1 1 
ATOM   14633 C CD2 . HIS E 1 422 ? 47.338  10.268  65.449 1.00 46.89  ? 624 HIS E CD2 1 
ATOM   14634 C CE1 . HIS E 1 422 ? 45.634  9.317   66.448 1.00 49.13  ? 624 HIS E CE1 1 
ATOM   14635 N NE2 . HIS E 1 422 ? 46.165  10.483  66.131 1.00 49.45  ? 624 HIS E NE2 1 
ATOM   14636 N N   . THR E 1 423 ? 46.455  7.814   61.887 1.00 39.92  ? 625 THR E N   1 
ATOM   14637 C CA  . THR E 1 423 ? 45.988  8.390   60.638 1.00 40.06  ? 625 THR E CA  1 
ATOM   14638 C C   . THR E 1 423 ? 44.492  8.633   60.717 1.00 40.22  ? 625 THR E C   1 
ATOM   14639 O O   . THR E 1 423 ? 43.809  8.162   61.629 1.00 39.97  ? 625 THR E O   1 
ATOM   14640 C CB  . THR E 1 423 ? 46.306  7.494   59.432 1.00 40.06  ? 625 THR E CB  1 
ATOM   14641 O OG1 . THR E 1 423 ? 45.796  6.175   59.663 1.00 39.57  ? 625 THR E OG1 1 
ATOM   14642 C CG2 . THR E 1 423 ? 47.801  7.434   59.163 1.00 39.03  ? 625 THR E CG2 1 
ATOM   14643 N N   . ASP E 1 424 ? 43.995  9.397   59.745 1.00 40.78  ? 626 ASP E N   1 
ATOM   14644 C CA  . ASP E 1 424 ? 42.565  9.661   59.666 1.00 41.16  ? 626 ASP E CA  1 
ATOM   14645 C C   . ASP E 1 424 ? 41.784  8.388   59.383 1.00 40.11  ? 626 ASP E C   1 
ATOM   14646 O O   . ASP E 1 424 ? 40.678  8.201   59.903 1.00 41.05  ? 626 ASP E O   1 
ATOM   14647 C CB  . ASP E 1 424 ? 42.292  10.712  58.592 1.00 42.02  ? 626 ASP E CB  1 
ATOM   14648 C CG  . ASP E 1 424 ? 42.730  12.092  59.013 1.00 45.93  ? 626 ASP E CG  1 
ATOM   14649 O OD1 . ASP E 1 424 ? 42.886  12.312  60.229 1.00 49.76  ? 626 ASP E OD1 1 
ATOM   14650 O OD2 . ASP E 1 424 ? 42.934  12.951  58.130 1.00 48.09  ? 626 ASP E OD2 1 
ATOM   14651 N N   . GLY E 1 425 ? 42.339  7.499   58.567 1.00 38.72  ? 627 GLY E N   1 
ATOM   14652 C CA  . GLY E 1 425 ? 41.643  6.273   58.232 1.00 36.22  ? 627 GLY E CA  1 
ATOM   14653 C C   . GLY E 1 425 ? 42.592  5.182   57.794 1.00 35.54  ? 627 GLY E C   1 
ATOM   14654 O O   . GLY E 1 425 ? 43.713  5.436   57.344 1.00 35.65  ? 627 GLY E O   1 
ATOM   14655 N N   . ASN E 1 426 ? 42.117  3.950   57.942 1.00 35.97  ? 628 ASN E N   1 
ATOM   14656 C CA  . ASN E 1 426 ? 42.821  2.766   57.479 1.00 35.59  ? 628 ASN E CA  1 
ATOM   14657 C C   . ASN E 1 426 ? 41.801  1.655   57.291 1.00 35.00  ? 628 ASN E C   1 
ATOM   14658 O O   . ASN E 1 426 ? 40.674  1.737   57.786 1.00 34.34  ? 628 ASN E O   1 
ATOM   14659 C CB  . ASN E 1 426 ? 43.941  2.364   58.448 1.00 36.25  ? 628 ASN E CB  1 
ATOM   14660 C CG  . ASN E 1 426 ? 43.443  2.109   59.860 1.00 35.65  ? 628 ASN E CG  1 
ATOM   14661 O OD1 . ASN E 1 426 ? 42.352  1.587   60.070 1.00 33.98  ? 628 ASN E OD1 1 
ATOM   14662 N ND2 . ASN E 1 426 ? 44.243  2.504   60.841 1.00 36.56  ? 628 ASN E ND2 1 
ATOM   14663 N N   . PHE E 1 427 ? 42.194  0.620   56.556 1.00 34.48  ? 629 PHE E N   1 
ATOM   14664 C CA  . PHE E 1 427 ? 41.308  -0.506  56.304 1.00 34.07  ? 629 PHE E CA  1 
ATOM   14665 C C   . PHE E 1 427 ? 41.997  -1.805  56.675 1.00 35.57  ? 629 PHE E C   1 
ATOM   14666 O O   . PHE E 1 427 ? 43.104  -2.080  56.202 1.00 35.55  ? 629 PHE E O   1 
ATOM   14667 C CB  . PHE E 1 427 ? 40.861  -0.562  54.847 1.00 30.57  ? 629 PHE E CB  1 
ATOM   14668 C CG  . PHE E 1 427 ? 40.003  -1.748  54.534 1.00 31.00  ? 629 PHE E CG  1 
ATOM   14669 C CD1 . PHE E 1 427 ? 38.661  -1.747  54.861 1.00 29.38  ? 629 PHE E CD1 1 
ATOM   14670 C CD2 . PHE E 1 427 ? 40.537  -2.865  53.920 1.00 30.69  ? 629 PHE E CD2 1 
ATOM   14671 C CE1 . PHE E 1 427 ? 37.869  -2.837  54.583 1.00 29.30  ? 629 PHE E CE1 1 
ATOM   14672 C CE2 . PHE E 1 427 ? 39.748  -3.955  53.638 1.00 30.78  ? 629 PHE E CE2 1 
ATOM   14673 C CZ  . PHE E 1 427 ? 38.412  -3.941  53.970 1.00 30.22  ? 629 PHE E CZ  1 
ATOM   14674 N N   . HIS E 1 428 ? 41.318  -2.610  57.491 1.00 34.68  ? 630 HIS E N   1 
ATOM   14675 C CA  . HIS E 1 428 ? 41.782  -3.910  57.951 1.00 35.79  ? 630 HIS E CA  1 
ATOM   14676 C C   . HIS E 1 428 ? 43.201  -3.735  58.476 1.00 36.32  ? 630 HIS E C   1 
ATOM   14677 O O   . HIS E 1 428 ? 44.165  -4.191  57.850 1.00 36.92  ? 630 HIS E O   1 
ATOM   14678 C CB  . HIS E 1 428 ? 41.707  -4.938  56.821 1.00 33.30  ? 630 HIS E CB  1 
ATOM   14679 C CG  . HIS E 1 428 ? 41.862  -6.356  57.275 1.00 34.74  ? 630 HIS E CG  1 
ATOM   14680 N ND1 . HIS E 1 428 ? 40.978  -6.958  58.144 1.00 35.33  ? 630 HIS E ND1 1 
ATOM   14681 C CD2 . HIS E 1 428 ? 42.780  -7.299  56.961 1.00 35.00  ? 630 HIS E CD2 1 
ATOM   14682 C CE1 . HIS E 1 428 ? 41.352  -8.206  58.356 1.00 35.82  ? 630 HIS E CE1 1 
ATOM   14683 N NE2 . HIS E 1 428 ? 42.442  -8.439  57.649 1.00 35.62  ? 630 HIS E NE2 1 
ATOM   14684 N N   . PRO E 1 429 ? 43.357  -3.076  59.623 1.00 40.83  ? 631 PRO E N   1 
ATOM   14685 C CA  . PRO E 1 429 ? 44.678  -2.609  60.065 1.00 40.45  ? 631 PRO E CA  1 
ATOM   14686 C C   . PRO E 1 429 ? 45.717  -3.699  60.272 1.00 40.43  ? 631 PRO E C   1 
ATOM   14687 O O   . PRO E 1 429 ? 46.887  -3.380  60.497 1.00 41.76  ? 631 PRO E O   1 
ATOM   14688 C CB  . PRO E 1 429 ? 44.362  -1.884  61.377 1.00 42.48  ? 631 PRO E CB  1 
ATOM   14689 C CG  . PRO E 1 429 ? 43.116  -2.516  61.861 1.00 41.91  ? 631 PRO E CG  1 
ATOM   14690 C CD  . PRO E 1 429 ? 42.317  -2.799  60.626 1.00 41.97  ? 631 PRO E CD  1 
ATOM   14691 N N   . SER E 1 430 ? 45.304  -4.963  60.254 1.00 40.79  ? 632 SER E N   1 
ATOM   14692 C CA  . SER E 1 430 ? 46.233  -6.069  60.434 1.00 40.17  ? 632 SER E CA  1 
ATOM   14693 C C   . SER E 1 430 ? 47.451  -5.892  59.526 1.00 39.47  ? 632 SER E C   1 
ATOM   14694 O O   . SER E 1 430 ? 47.290  -5.656  58.321 1.00 39.53  ? 632 SER E O   1 
ATOM   14695 C CB  . SER E 1 430 ? 45.538  -7.395  60.125 1.00 38.94  ? 632 SER E CB  1 
ATOM   14696 O OG  . SER E 1 430 ? 46.438  -8.483  60.232 1.00 43.29  ? 632 SER E OG  1 
ATOM   14697 N N   . PRO E 1 431 ? 48.667  -5.991  60.060 1.00 41.12  ? 633 PRO E N   1 
ATOM   14698 C CA  . PRO E 1 431 ? 49.854  -5.695  59.253 1.00 40.83  ? 633 PRO E CA  1 
ATOM   14699 C C   . PRO E 1 431 ? 50.117  -6.771  58.215 1.00 40.89  ? 633 PRO E C   1 
ATOM   14700 O O   . PRO E 1 431 ? 49.734  -7.932  58.372 1.00 41.31  ? 633 PRO E O   1 
ATOM   14701 C CB  . PRO E 1 431 ? 50.978  -5.641  60.290 1.00 39.68  ? 633 PRO E CB  1 
ATOM   14702 C CG  . PRO E 1 431 ? 50.514  -6.542  61.370 1.00 40.85  ? 633 PRO E CG  1 
ATOM   14703 C CD  . PRO E 1 431 ? 49.021  -6.381  61.434 1.00 39.92  ? 633 PRO E CD  1 
ATOM   14704 N N   . LEU E 1 432 ? 50.802  -6.368  57.148 1.00 38.68  ? 634 LEU E N   1 
ATOM   14705 C CA  . LEU E 1 432 ? 50.956  -7.227  55.984 1.00 38.68  ? 634 LEU E CA  1 
ATOM   14706 C C   . LEU E 1 432 ? 52.086  -8.235  56.116 1.00 39.95  ? 634 LEU E C   1 
ATOM   14707 O O   . LEU E 1 432 ? 52.122  -9.198  55.345 1.00 39.98  ? 634 LEU E O   1 
ATOM   14708 C CB  . LEU E 1 432 ? 51.168  -6.373  54.736 1.00 41.86  ? 634 LEU E CB  1 
ATOM   14709 C CG  . LEU E 1 432 ? 49.945  -5.542  54.360 1.00 39.93  ? 634 LEU E CG  1 
ATOM   14710 C CD1 . LEU E 1 432 ? 50.264  -4.609  53.214 1.00 39.12  ? 634 LEU E CD1 1 
ATOM   14711 C CD2 . LEU E 1 432 ? 48.800  -6.463  53.999 1.00 37.16  ? 634 LEU E CD2 1 
ATOM   14712 N N   . MET E 1 433 ? 53.011  -8.047  57.054 1.00 45.00  ? 635 MET E N   1 
ATOM   14713 C CA  . MET E 1 433 ? 54.014  -9.080  57.276 1.00 45.79  ? 635 MET E CA  1 
ATOM   14714 C C   . MET E 1 433 ? 53.539  -10.152 58.243 1.00 45.95  ? 635 MET E C   1 
ATOM   14715 O O   . MET E 1 433 ? 54.281  -11.104 58.500 1.00 45.46  ? 635 MET E O   1 
ATOM   14716 C CB  . MET E 1 433 ? 55.326  -8.476  57.785 1.00 37.50  ? 635 MET E CB  1 
ATOM   14717 C CG  . MET E 1 433 ? 56.029  -7.577  56.784 1.00 39.90  ? 635 MET E CG  1 
ATOM   14718 S SD  . MET E 1 433 ? 57.722  -7.173  57.262 1.00 45.62  ? 635 MET E SD  1 
ATOM   14719 C CE  . MET E 1 433 ? 57.488  -6.027  58.610 1.00 44.70  ? 635 MET E CE  1 
ATOM   14720 N N   . GLY E 1 434 ? 52.329  -10.027 58.764 1.00 47.70  ? 636 GLY E N   1 
ATOM   14721 C CA  . GLY E 1 434 ? 51.781  -10.964 59.717 1.00 46.75  ? 636 GLY E CA  1 
ATOM   14722 C C   . GLY E 1 434 ? 51.765  -10.392 61.125 1.00 46.53  ? 636 GLY E C   1 
ATOM   14723 O O   . GLY E 1 434 ? 52.530  -9.491  61.478 1.00 47.77  ? 636 GLY E O   1 
ATOM   14724 N N   . GLY E 1 435 ? 50.873  -10.940 61.938 1.00 47.80  ? 637 GLY E N   1 
ATOM   14725 C CA  . GLY E 1 435 ? 50.777  -10.557 63.327 1.00 46.01  ? 637 GLY E CA  1 
ATOM   14726 C C   . GLY E 1 435 ? 49.584  -9.676  63.641 1.00 44.57  ? 637 GLY E C   1 
ATOM   14727 O O   . GLY E 1 435 ? 48.680  -9.468  62.830 1.00 44.18  ? 637 GLY E O   1 
ATOM   14728 N N   . PHE E 1 436 ? 49.598  -9.149  64.862 1.00 45.16  ? 638 PHE E N   1 
ATOM   14729 C CA  . PHE E 1 436 ? 48.477  -8.417  65.436 1.00 44.94  ? 638 PHE E CA  1 
ATOM   14730 C C   . PHE E 1 436 ? 48.726  -6.921  65.304 1.00 46.61  ? 638 PHE E C   1 
ATOM   14731 O O   . PHE E 1 436 ? 49.673  -6.394  65.897 1.00 48.54  ? 638 PHE E O   1 
ATOM   14732 C CB  . PHE E 1 436 ? 48.291  -8.785  66.907 1.00 46.33  ? 638 PHE E CB  1 
ATOM   14733 C CG  . PHE E 1 436 ? 48.027  -10.242 67.142 1.00 45.77  ? 638 PHE E CG  1 
ATOM   14734 C CD1 . PHE E 1 436 ? 46.746  -10.750 67.063 1.00 45.15  ? 638 PHE E CD1 1 
ATOM   14735 C CD2 . PHE E 1 436 ? 49.066  -11.103 67.446 1.00 45.43  ? 638 PHE E CD2 1 
ATOM   14736 C CE1 . PHE E 1 436 ? 46.506  -12.089 67.285 1.00 45.56  ? 638 PHE E CE1 1 
ATOM   14737 C CE2 . PHE E 1 436 ? 48.830  -12.443 67.665 1.00 45.69  ? 638 PHE E CE2 1 
ATOM   14738 C CZ  . PHE E 1 436 ? 47.549  -12.935 67.585 1.00 45.28  ? 638 PHE E CZ  1 
ATOM   14739 N N   . GLY E 1 437 ? 47.881  -6.240  64.534 1.00 45.12  ? 639 GLY E N   1 
ATOM   14740 C CA  . GLY E 1 437 ? 47.945  -4.790  64.471 1.00 45.51  ? 639 GLY E CA  1 
ATOM   14741 C C   . GLY E 1 437 ? 47.383  -4.166  65.738 1.00 46.59  ? 639 GLY E C   1 
ATOM   14742 O O   . GLY E 1 437 ? 46.317  -4.542  66.223 1.00 46.62  ? 639 GLY E O   1 
ATOM   14743 N N   . MET E 1 438 ? 48.116  -3.193  66.274 1.00 48.82  ? 640 MET E N   1 
ATOM   14744 C CA  . MET E 1 438 ? 47.749  -2.576  67.541 1.00 49.43  ? 640 MET E CA  1 
ATOM   14745 C C   . MET E 1 438 ? 48.018  -1.082  67.490 1.00 50.14  ? 640 MET E C   1 
ATOM   14746 O O   . MET E 1 438 ? 49.089  -0.656  67.049 1.00 50.17  ? 640 MET E O   1 
ATOM   14747 C CB  . MET E 1 438 ? 48.516  -3.207  68.706 1.00 51.50  ? 640 MET E CB  1 
ATOM   14748 C CG  . MET E 1 438 ? 48.139  -4.650  68.986 1.00 56.01  ? 640 MET E CG  1 
ATOM   14749 S SD  . MET E 1 438 ? 49.090  -5.363  70.331 1.00 60.48  ? 640 MET E SD  1 
ATOM   14750 C CE  . MET E 1 438 ? 48.394  -4.471  71.715 1.00 60.37  ? 640 MET E CE  1 
ATOM   14751 N N   . LYS E 1 439 ? 47.043  -0.291  67.943 1.00 54.90  ? 641 LYS E N   1 
ATOM   14752 C CA  . LYS E 1 439 ? 47.247  1.150   68.022 1.00 56.84  ? 641 LYS E CA  1 
ATOM   14753 C C   . LYS E 1 439 ? 48.100  1.531   69.223 1.00 56.79  ? 641 LYS E C   1 
ATOM   14754 O O   . LYS E 1 439 ? 48.867  2.497   69.157 1.00 57.51  ? 641 LYS E O   1 
ATOM   14755 C CB  . LYS E 1 439 ? 45.901  1.870   68.075 1.00 54.79  ? 641 LYS E CB  1 
ATOM   14756 C CG  . LYS E 1 439 ? 45.131  1.808   66.773 1.00 60.69  ? 641 LYS E CG  1 
ATOM   14757 C CD  . LYS E 1 439 ? 43.910  2.707   66.804 1.00 67.11  ? 641 LYS E CD  1 
ATOM   14758 C CE  . LYS E 1 439 ? 42.892  2.216   67.816 1.00 69.48  ? 641 LYS E CE  1 
ATOM   14759 N NZ  . LYS E 1 439 ? 41.646  3.030   67.780 1.00 70.23  ? 641 LYS E NZ  1 
ATOM   14760 N N   . HIS E 1 440 ? 47.985  0.787   70.323 1.00 55.78  ? 642 HIS E N   1 
ATOM   14761 C CA  . HIS E 1 440 ? 48.799  0.988   71.518 1.00 55.62  ? 642 HIS E CA  1 
ATOM   14762 C C   . HIS E 1 440 ? 49.510  -0.324  71.826 1.00 53.97  ? 642 HIS E C   1 
ATOM   14763 O O   . HIS E 1 440 ? 49.101  -1.071  72.727 1.00 54.08  ? 642 HIS E O   1 
ATOM   14764 C CB  . HIS E 1 440 ? 47.950  1.455   72.697 1.00 54.23  ? 642 HIS E CB  1 
ATOM   14765 C CG  . HIS E 1 440 ? 47.246  2.752   72.453 1.00 59.34  ? 642 HIS E CG  1 
ATOM   14766 N ND1 . HIS E 1 440 ? 47.912  3.956   72.379 1.00 60.60  ? 642 HIS E ND1 1 
ATOM   14767 C CD2 . HIS E 1 440 ? 45.936  3.034   72.263 1.00 60.43  ? 642 HIS E CD2 1 
ATOM   14768 C CE1 . HIS E 1 440 ? 47.042  4.924   72.155 1.00 61.79  ? 642 HIS E CE1 1 
ATOM   14769 N NE2 . HIS E 1 440 ? 45.836  4.391   72.081 1.00 63.01  ? 642 HIS E NE2 1 
ATOM   14770 N N   . PRO E 1 441 ? 50.572  -0.639  71.093 1.00 53.47  ? 643 PRO E N   1 
ATOM   14771 C CA  . PRO E 1 441 ? 51.317  -1.866  71.347 1.00 51.88  ? 643 PRO E CA  1 
ATOM   14772 C C   . PRO E 1 441 ? 52.356  -1.646  72.433 1.00 51.14  ? 643 PRO E C   1 
ATOM   14773 O O   . PRO E 1 441 ? 52.481  -0.531  72.960 1.00 51.22  ? 643 PRO E O   1 
ATOM   14774 C CB  . PRO E 1 441 ? 51.972  -2.152  69.988 1.00 50.84  ? 643 PRO E CB  1 
ATOM   14775 C CG  . PRO E 1 441 ? 52.189  -0.806  69.407 1.00 50.66  ? 643 PRO E CG  1 
ATOM   14776 C CD  . PRO E 1 441 ? 51.096  0.092   69.926 1.00 50.62  ? 643 PRO E CD  1 
ATOM   14777 N N   . PRO E 1 442 ? 53.117  -2.689  72.812 1.00 50.55  ? 644 PRO E N   1 
ATOM   14778 C CA  . PRO E 1 442 ? 54.242  -2.535  73.743 1.00 50.04  ? 644 PRO E CA  1 
ATOM   14779 C C   . PRO E 1 442 ? 55.238  -1.449  73.333 1.00 50.33  ? 644 PRO E C   1 
ATOM   14780 O O   . PRO E 1 442 ? 55.332  -1.134  72.149 1.00 50.06  ? 644 PRO E O   1 
ATOM   14781 C CB  . PRO E 1 442 ? 54.907  -3.908  73.706 1.00 49.38  ? 644 PRO E CB  1 
ATOM   14782 C CG  . PRO E 1 442 ? 53.801  -4.840  73.409 1.00 49.73  ? 644 PRO E CG  1 
ATOM   14783 C CD  . PRO E 1 442 ? 52.833  -4.109  72.532 1.00 49.46  ? 644 PRO E CD  1 
ATOM   14784 N N   . ASP F 1 17  ? 3.516   -39.984 72.602 1.00 69.25  ? 219 ASP F N   1 
ATOM   14785 C CA  . ASP F 1 17  ? 2.414   -40.124 73.544 1.00 69.50  ? 219 ASP F CA  1 
ATOM   14786 C C   . ASP F 1 17  ? 1.539   -41.324 73.192 1.00 67.21  ? 219 ASP F C   1 
ATOM   14787 O O   . ASP F 1 17  ? 1.365   -42.234 74.002 1.00 67.25  ? 219 ASP F O   1 
ATOM   14788 C CB  . ASP F 1 17  ? 1.574   -38.847 73.579 1.00 67.41  ? 219 ASP F CB  1 
ATOM   14789 C CG  . ASP F 1 17  ? 0.423   -38.932 74.560 1.00 71.08  ? 219 ASP F CG  1 
ATOM   14790 O OD1 . ASP F 1 17  ? 0.683   -39.004 75.779 1.00 72.86  ? 219 ASP F OD1 1 
ATOM   14791 O OD2 . ASP F 1 17  ? -0.744  -38.923 74.113 1.00 72.18  ? 219 ASP F OD2 1 
ATOM   14792 N N   . GLY F 1 18  ? 0.990   -41.323 71.980 1.00 70.28  ? 220 GLY F N   1 
ATOM   14793 C CA  . GLY F 1 18  ? 0.145   -42.416 71.538 1.00 64.90  ? 220 GLY F CA  1 
ATOM   14794 C C   . GLY F 1 18  ? -0.019  -42.406 70.035 1.00 61.55  ? 220 GLY F C   1 
ATOM   14795 O O   . GLY F 1 18  ? 0.257   -41.408 69.362 1.00 62.28  ? 220 GLY F O   1 
ATOM   14796 N N   . VAL F 1 19  ? -0.484  -43.542 69.512 1.00 61.23  ? 221 VAL F N   1 
ATOM   14797 C CA  . VAL F 1 19  ? -0.680  -43.667 68.072 1.00 57.00  ? 221 VAL F CA  1 
ATOM   14798 C C   . VAL F 1 19  ? -1.942  -42.935 67.635 1.00 55.87  ? 221 VAL F C   1 
ATOM   14799 O O   . VAL F 1 19  ? -1.966  -42.282 66.585 1.00 56.73  ? 221 VAL F O   1 
ATOM   14800 C CB  . VAL F 1 19  ? -0.716  -45.153 67.668 1.00 58.32  ? 221 VAL F CB  1 
ATOM   14801 C CG1 . VAL F 1 19  ? -1.045  -45.297 66.195 1.00 57.57  ? 221 VAL F CG1 1 
ATOM   14802 C CG2 . VAL F 1 19  ? 0.613   -45.817 67.980 1.00 58.35  ? 221 VAL F CG2 1 
ATOM   14803 N N   . GLY F 1 20  ? -3.005  -43.024 68.425 1.00 59.16  ? 222 GLY F N   1 
ATOM   14804 C CA  . GLY F 1 20  ? -4.274  -42.424 68.084 1.00 56.65  ? 222 GLY F CA  1 
ATOM   14805 C C   . GLY F 1 20  ? -4.471  -41.000 68.552 1.00 56.38  ? 222 GLY F C   1 
ATOM   14806 O O   . GLY F 1 20  ? -5.588  -40.481 68.458 1.00 56.61  ? 222 GLY F O   1 
ATOM   14807 N N   . SER F 1 21  ? -3.427  -40.351 69.055 1.00 55.65  ? 223 SER F N   1 
ATOM   14808 C CA  . SER F 1 21  ? -3.497  -38.974 69.518 1.00 54.21  ? 223 SER F CA  1 
ATOM   14809 C C   . SER F 1 21  ? -2.654  -38.088 68.616 1.00 52.93  ? 223 SER F C   1 
ATOM   14810 O O   . SER F 1 21  ? -1.490  -38.395 68.342 1.00 54.62  ? 223 SER F O   1 
ATOM   14811 C CB  . SER F 1 21  ? -3.010  -38.850 70.962 1.00 54.45  ? 223 SER F CB  1 
ATOM   14812 O OG  . SER F 1 21  ? -3.017  -37.500 71.388 1.00 59.49  ? 223 SER F OG  1 
ATOM   14813 N N   . SER F 1 22  ? -3.246  -36.989 68.157 1.00 53.78  ? 224 SER F N   1 
ATOM   14814 C CA  . SER F 1 22  ? -2.527  -36.032 67.331 1.00 52.06  ? 224 SER F CA  1 
ATOM   14815 C C   . SER F 1 22  ? -1.475  -35.306 68.159 1.00 50.48  ? 224 SER F C   1 
ATOM   14816 O O   . SER F 1 22  ? -1.705  -34.962 69.322 1.00 49.18  ? 224 SER F O   1 
ATOM   14817 C CB  . SER F 1 22  ? -3.497  -35.027 66.711 1.00 44.45  ? 224 SER F CB  1 
ATOM   14818 O OG  . SER F 1 22  ? -2.807  -34.065 65.938 1.00 48.60  ? 224 SER F OG  1 
ATOM   14819 N N   . SER F 1 23  ? -0.308  -35.094 67.558 1.00 46.77  ? 225 SER F N   1 
ATOM   14820 C CA  . SER F 1 23  ? 0.813   -34.446 68.223 1.00 46.11  ? 225 SER F CA  1 
ATOM   14821 C C   . SER F 1 23  ? 0.916   -32.958 67.917 1.00 45.89  ? 225 SER F C   1 
ATOM   14822 O O   . SER F 1 23  ? 1.803   -32.290 68.456 1.00 47.00  ? 225 SER F O   1 
ATOM   14823 C CB  . SER F 1 23  ? 2.119   -35.148 67.842 1.00 44.76  ? 225 SER F CB  1 
ATOM   14824 O OG  . SER F 1 23  ? 2.355   -35.070 66.448 1.00 46.67  ? 225 SER F OG  1 
ATOM   14825 N N   . GLY F 1 24  ? 0.038   -32.423 67.076 1.00 43.40  ? 226 GLY F N   1 
ATOM   14826 C CA  . GLY F 1 24  ? 0.072   -31.008 66.752 1.00 43.07  ? 226 GLY F CA  1 
ATOM   14827 C C   . GLY F 1 24  ? -1.140  -30.629 65.933 1.00 43.14  ? 226 GLY F C   1 
ATOM   14828 O O   . GLY F 1 24  ? -1.968  -31.472 65.581 1.00 43.77  ? 226 GLY F O   1 
ATOM   14829 N N   . ASN F 1 25  ? -1.240  -29.336 65.644 1.00 35.22  ? 227 ASN F N   1 
ATOM   14830 C CA  . ASN F 1 25  ? -2.311  -28.806 64.816 1.00 35.55  ? 227 ASN F CA  1 
ATOM   14831 C C   . ASN F 1 25  ? -1.723  -28.066 63.624 1.00 37.20  ? 227 ASN F C   1 
ATOM   14832 O O   . ASN F 1 25  ? -0.513  -27.864 63.520 1.00 39.65  ? 227 ASN F O   1 
ATOM   14833 C CB  . ASN F 1 25  ? -3.219  -27.871 65.621 1.00 37.19  ? 227 ASN F CB  1 
ATOM   14834 C CG  . ASN F 1 25  ? -4.051  -28.609 66.641 1.00 37.91  ? 227 ASN F CG  1 
ATOM   14835 O OD1 . ASN F 1 25  ? -4.324  -29.798 66.494 1.00 38.59  ? 227 ASN F OD1 1 
ATOM   14836 N ND2 . ASN F 1 25  ? -4.456  -27.908 67.690 1.00 38.34  ? 227 ASN F ND2 1 
ATOM   14837 N N   . TRP F 1 26  ? -2.604  -27.625 62.736 1.00 30.88  ? 228 TRP F N   1 
ATOM   14838 C CA  . TRP F 1 26  ? -2.201  -26.959 61.506 1.00 31.40  ? 228 TRP F CA  1 
ATOM   14839 C C   . TRP F 1 26  ? -2.211  -25.457 61.750 1.00 32.89  ? 228 TRP F C   1 
ATOM   14840 O O   . TRP F 1 26  ? -3.278  -24.866 61.935 1.00 33.31  ? 228 TRP F O   1 
ATOM   14841 C CB  . TRP F 1 26  ? -3.158  -27.321 60.372 1.00 28.51  ? 228 TRP F CB  1 
ATOM   14842 C CG  . TRP F 1 26  ? -2.812  -26.746 59.036 1.00 27.79  ? 228 TRP F CG  1 
ATOM   14843 C CD1 . TRP F 1 26  ? -3.221  -25.551 58.539 1.00 27.19  ? 228 TRP F CD1 1 
ATOM   14844 C CD2 . TRP F 1 26  ? -2.078  -27.387 57.985 1.00 27.25  ? 228 TRP F CD2 1 
ATOM   14845 N NE1 . TRP F 1 26  ? -2.744  -25.377 57.266 1.00 27.57  ? 228 TRP F NE1 1 
ATOM   14846 C CE2 . TRP F 1 26  ? -2.043  -26.494 56.899 1.00 27.72  ? 228 TRP F CE2 1 
ATOM   14847 C CE3 . TRP F 1 26  ? -1.435  -28.621 57.862 1.00 27.05  ? 228 TRP F CE3 1 
ATOM   14848 C CZ2 . TRP F 1 26  ? -1.388  -26.791 55.711 1.00 28.10  ? 228 TRP F CZ2 1 
ATOM   14849 C CZ3 . TRP F 1 26  ? -0.787  -28.912 56.684 1.00 27.85  ? 228 TRP F CZ3 1 
ATOM   14850 C CH2 . TRP F 1 26  ? -0.766  -28.002 55.624 1.00 28.06  ? 228 TRP F CH2 1 
ATOM   14851 N N   . HIS F 1 27  ? -1.036  -24.840 61.757 1.00 29.54  ? 229 HIS F N   1 
ATOM   14852 C CA  . HIS F 1 27  ? -0.922  -23.403 61.975 1.00 32.53  ? 229 HIS F CA  1 
ATOM   14853 C C   . HIS F 1 27  ? -0.366  -22.754 60.716 1.00 34.15  ? 229 HIS F C   1 
ATOM   14854 O O   . HIS F 1 27  ? 0.800   -22.963 60.367 1.00 35.25  ? 229 HIS F O   1 
ATOM   14855 C CB  . HIS F 1 27  ? -0.042  -23.096 63.183 1.00 33.60  ? 229 HIS F CB  1 
ATOM   14856 C CG  . HIS F 1 27  ? -0.627  -23.547 64.484 1.00 37.76  ? 229 HIS F CG  1 
ATOM   14857 N ND1 . HIS F 1 27  ? -0.486  -24.832 64.960 1.00 38.60  ? 229 HIS F ND1 1 
ATOM   14858 C CD2 . HIS F 1 27  ? -1.362  -22.883 65.407 1.00 39.44  ? 229 HIS F CD2 1 
ATOM   14859 C CE1 . HIS F 1 27  ? -1.102  -24.939 66.123 1.00 40.10  ? 229 HIS F CE1 1 
ATOM   14860 N NE2 . HIS F 1 27  ? -1.644  -23.771 66.416 1.00 41.56  ? 229 HIS F NE2 1 
ATOM   14861 N N   . CYS F 1 28  ? -1.162  -21.919 60.068 1.00 26.78  ? 230 CYS F N   1 
ATOM   14862 C CA  . CYS F 1 28  ? -0.697  -21.294 58.849 1.00 29.57  ? 230 CYS F CA  1 
ATOM   14863 C C   . CYS F 1 28  ? -1.295  -19.914 58.593 1.00 30.99  ? 230 CYS F C   1 
ATOM   14864 O O   . CYS F 1 28  ? -2.037  -19.729 57.638 1.00 32.38  ? 230 CYS F O   1 
ATOM   14865 C CB  . CYS F 1 28  ? -1.004  -22.227 57.684 1.00 28.67  ? 230 CYS F CB  1 
ATOM   14866 S SG  . CYS F 1 28  ? 0.116   -22.112 56.284 1.00 31.72  ? 230 CYS F SG  1 
ATOM   14867 N N   . ASP F 1 29  ? -0.983  -18.946 59.444 1.00 33.10  ? 231 ASP F N   1 
ATOM   14868 C CA  . ASP F 1 29  ? -1.494  -17.592 59.256 1.00 35.30  ? 231 ASP F CA  1 
ATOM   14869 C C   . ASP F 1 29  ? -0.484  -16.524 59.665 1.00 33.20  ? 231 ASP F C   1 
ATOM   14870 O O   . ASP F 1 29  ? 0.421   -16.790 60.445 1.00 33.55  ? 231 ASP F O   1 
ATOM   14871 C CB  . ASP F 1 29  ? -2.821  -17.393 59.990 1.00 34.80  ? 231 ASP F CB  1 
ATOM   14872 C CG  . ASP F 1 29  ? -2.642  -17.175 61.470 1.00 38.93  ? 231 ASP F CG  1 
ATOM   14873 O OD1 . ASP F 1 29  ? -1.645  -17.665 62.031 1.00 41.22  ? 231 ASP F OD1 1 
ATOM   14874 O OD2 . ASP F 1 29  ? -3.507  -16.518 62.076 1.00 41.20  ? 231 ASP F OD2 1 
ATOM   14875 N N   . SER F 1 30  ? -0.643  -15.316 59.138 1.00 32.91  ? 232 SER F N   1 
ATOM   14876 C CA  . SER F 1 30  ? 0.261   -14.220 59.457 1.00 32.07  ? 232 SER F CA  1 
ATOM   14877 C C   . SER F 1 30  ? -0.466  -13.133 60.225 1.00 31.59  ? 232 SER F C   1 
ATOM   14878 O O   . SER F 1 30  ? -1.562  -12.742 59.858 1.00 31.89  ? 232 SER F O   1 
ATOM   14879 C CB  . SER F 1 30  ? 0.854   -13.630 58.185 1.00 28.02  ? 232 SER F CB  1 
ATOM   14880 O OG  . SER F 1 30  ? -0.115  -12.877 57.485 1.00 28.07  ? 232 SER F OG  1 
ATOM   14881 N N   . GLN F 1 31  ? 0.144   -12.652 61.300 1.00 33.53  ? 233 GLN F N   1 
ATOM   14882 C CA  . GLN F 1 31  ? -0.459  -11.610 62.115 1.00 33.18  ? 233 GLN F CA  1 
ATOM   14883 C C   . GLN F 1 31  ? 0.342   -10.327 62.061 1.00 31.45  ? 233 GLN F C   1 
ATOM   14884 O O   . GLN F 1 31  ? 1.540   -10.335 62.294 1.00 31.22  ? 233 GLN F O   1 
ATOM   14885 C CB  . GLN F 1 31  ? -0.540  -12.060 63.569 1.00 31.81  ? 233 GLN F CB  1 
ATOM   14886 C CG  . GLN F 1 31  ? -1.218  -13.396 63.775 1.00 39.31  ? 233 GLN F CG  1 
ATOM   14887 C CD  . GLN F 1 31  ? -1.500  -13.668 65.236 1.00 43.42  ? 233 GLN F CD  1 
ATOM   14888 O OE1 . GLN F 1 31  ? -0.867  -13.089 66.119 1.00 45.18  ? 233 GLN F OE1 1 
ATOM   14889 N NE2 . GLN F 1 31  ? -2.458  -14.549 65.500 1.00 44.69  ? 233 GLN F NE2 1 
ATOM   14890 N N   . TRP F 1 32  ? -0.322  -9.218  61.769 1.00 31.40  ? 234 TRP F N   1 
ATOM   14891 C CA  . TRP F 1 32  ? 0.360   -7.941  61.720 1.00 30.96  ? 234 TRP F CA  1 
ATOM   14892 C C   . TRP F 1 32  ? 0.002   -7.126  62.943 1.00 32.52  ? 234 TRP F C   1 
ATOM   14893 O O   . TRP F 1 32  ? -1.129  -6.678  63.082 1.00 32.71  ? 234 TRP F O   1 
ATOM   14894 C CB  . TRP F 1 32  ? -0.077  -7.173  60.482 1.00 26.16  ? 234 TRP F CB  1 
ATOM   14895 C CG  . TRP F 1 32  ? 0.324   -7.808  59.206 1.00 24.39  ? 234 TRP F CG  1 
ATOM   14896 C CD1 . TRP F 1 32  ? -0.251  -8.884  58.613 1.00 23.80  ? 234 TRP F CD1 1 
ATOM   14897 C CD2 . TRP F 1 32  ? 1.388   -7.398  58.349 1.00 22.96  ? 234 TRP F CD2 1 
ATOM   14898 N NE1 . TRP F 1 32  ? 0.390   -9.176  57.440 1.00 21.45  ? 234 TRP F NE1 1 
ATOM   14899 C CE2 . TRP F 1 32  ? 1.402   -8.275  57.255 1.00 21.89  ? 234 TRP F CE2 1 
ATOM   14900 C CE3 . TRP F 1 32  ? 2.335   -6.374  58.403 1.00 21.03  ? 234 TRP F CE3 1 
ATOM   14901 C CZ2 . TRP F 1 32  ? 2.325   -8.163  56.227 1.00 21.10  ? 234 TRP F CZ2 1 
ATOM   14902 C CZ3 . TRP F 1 32  ? 3.246   -6.263  57.380 1.00 20.98  ? 234 TRP F CZ3 1 
ATOM   14903 C CH2 . TRP F 1 32  ? 3.236   -7.151  56.308 1.00 21.38  ? 234 TRP F CH2 1 
ATOM   14904 N N   . LEU F 1 33  ? 0.962   -6.930  63.834 1.00 36.37  ? 235 LEU F N   1 
ATOM   14905 C CA  . LEU F 1 33  ? 0.709   -6.133  65.021 1.00 38.44  ? 235 LEU F CA  1 
ATOM   14906 C C   . LEU F 1 33  ? 1.806   -5.109  65.243 1.00 39.44  ? 235 LEU F C   1 
ATOM   14907 O O   . LEU F 1 33  ? 2.963   -5.469  65.417 1.00 40.48  ? 235 LEU F O   1 
ATOM   14908 C CB  . LEU F 1 33  ? 0.546   -7.036  66.240 1.00 40.54  ? 235 LEU F CB  1 
ATOM   14909 C CG  . LEU F 1 33  ? 1.272   -8.379  66.185 1.00 42.54  ? 235 LEU F CG  1 
ATOM   14910 C CD1 . LEU F 1 33  ? 2.713   -8.253  66.646 1.00 42.40  ? 235 LEU F CD1 1 
ATOM   14911 C CD2 . LEU F 1 33  ? 0.525   -9.426  66.995 1.00 42.93  ? 235 LEU F CD2 1 
ATOM   14912 N N   . GLY F 1 34  ? 1.437   -3.837  65.297 1.00 35.03  ? 236 GLY F N   1 
ATOM   14913 C CA  . GLY F 1 34  ? 2.417   -2.790  65.498 1.00 35.82  ? 236 GLY F CA  1 
ATOM   14914 C C   . GLY F 1 34  ? 3.466   -2.805  64.408 1.00 36.54  ? 236 GLY F C   1 
ATOM   14915 O O   . GLY F 1 34  ? 3.145   -2.796  63.225 1.00 37.55  ? 236 GLY F O   1 
ATOM   14916 N N   . ASP F 1 35  ? 4.729   -2.815  64.818 1.00 35.89  ? 237 ASP F N   1 
ATOM   14917 C CA  . ASP F 1 35  ? 5.848   -2.834  63.889 1.00 36.26  ? 237 ASP F CA  1 
ATOM   14918 C C   . ASP F 1 35  ? 6.454   -4.226  63.792 1.00 33.55  ? 237 ASP F C   1 
ATOM   14919 O O   . ASP F 1 35  ? 7.658   -4.373  63.661 1.00 32.53  ? 237 ASP F O   1 
ATOM   14920 C CB  . ASP F 1 35  ? 6.925   -1.869  64.365 1.00 36.99  ? 237 ASP F CB  1 
ATOM   14921 C CG  . ASP F 1 35  ? 7.436   -2.218  65.742 1.00 43.84  ? 237 ASP F CG  1 
ATOM   14922 O OD1 . ASP F 1 35  ? 6.602   -2.404  66.653 1.00 47.13  ? 237 ASP F OD1 1 
ATOM   14923 O OD2 . ASP F 1 35  ? 8.667   -2.316  65.916 1.00 46.01  ? 237 ASP F OD2 1 
ATOM   14924 N N   . ARG F 1 36  ? 5.611   -5.242  63.865 1.00 36.87  ? 238 ARG F N   1 
ATOM   14925 C CA  . ARG F 1 36  ? 6.049   -6.624  63.791 1.00 35.21  ? 238 ARG F CA  1 
ATOM   14926 C C   . ARG F 1 36  ? 5.115   -7.504  62.987 1.00 31.41  ? 238 ARG F C   1 
ATOM   14927 O O   . ARG F 1 36  ? 3.910   -7.302  62.993 1.00 30.85  ? 238 ARG F O   1 
ATOM   14928 C CB  . ARG F 1 36  ? 6.236   -7.192  65.195 1.00 35.54  ? 238 ARG F CB  1 
ATOM   14929 C CG  . ARG F 1 36  ? 7.533   -6.742  65.834 1.00 45.67  ? 238 ARG F CG  1 
ATOM   14930 C CD  . ARG F 1 36  ? 7.695   -7.277  67.241 1.00 53.60  ? 238 ARG F CD  1 
ATOM   14931 N NE  . ARG F 1 36  ? 9.107   -7.432  67.578 1.00 61.91  ? 238 ARG F NE  1 
ATOM   14932 C CZ  . ARG F 1 36  ? 9.969   -6.427  67.656 1.00 65.03  ? 238 ARG F CZ  1 
ATOM   14933 N NH1 . ARG F 1 36  ? 11.234  -6.660  67.967 1.00 66.85  ? 238 ARG F NH1 1 
ATOM   14934 N NH2 . ARG F 1 36  ? 9.567   -5.188  67.421 1.00 64.81  ? 238 ARG F NH2 1 
ATOM   14935 N N   . VAL F 1 37  ? 5.683   -8.467  62.273 1.00 34.55  ? 239 VAL F N   1 
ATOM   14936 C CA  . VAL F 1 37  ? 4.885   -9.407  61.508 1.00 31.19  ? 239 VAL F CA  1 
ATOM   14937 C C   . VAL F 1 37  ? 5.280   -10.806 61.923 1.00 29.89  ? 239 VAL F C   1 
ATOM   14938 O O   . VAL F 1 37  ? 6.456   -11.134 61.942 1.00 28.75  ? 239 VAL F O   1 
ATOM   14939 C CB  . VAL F 1 37  ? 5.140   -9.301  60.000 1.00 27.14  ? 239 VAL F CB  1 
ATOM   14940 C CG1 . VAL F 1 37  ? 3.924   -9.785  59.233 1.00 24.62  ? 239 VAL F CG1 1 
ATOM   14941 C CG2 . VAL F 1 37  ? 5.486   -7.881  59.616 1.00 29.84  ? 239 VAL F CG2 1 
ATOM   14942 N N   . ILE F 1 38  ? 4.304   -11.633 62.259 1.00 31.03  ? 240 ILE F N   1 
ATOM   14943 C CA  . ILE F 1 38  ? 4.605   -13.002 62.618 1.00 29.85  ? 240 ILE F CA  1 
ATOM   14944 C C   . ILE F 1 38  ? 3.978   -13.873 61.554 1.00 30.58  ? 240 ILE F C   1 
ATOM   14945 O O   . ILE F 1 38  ? 2.772   -13.826 61.347 1.00 31.38  ? 240 ILE F O   1 
ATOM   14946 C CB  . ILE F 1 38  ? 4.020   -13.378 63.982 1.00 32.27  ? 240 ILE F CB  1 
ATOM   14947 C CG1 . ILE F 1 38  ? 4.671   -12.547 65.081 1.00 32.04  ? 240 ILE F CG1 1 
ATOM   14948 C CG2 . ILE F 1 38  ? 4.243   -14.850 64.257 1.00 30.07  ? 240 ILE F CG2 1 
ATOM   14949 C CD1 . ILE F 1 38  ? 4.031   -12.728 66.436 1.00 34.11  ? 240 ILE F CD1 1 
ATOM   14950 N N   . THR F 1 39  ? 4.792   -14.675 60.881 1.00 28.98  ? 241 THR F N   1 
ATOM   14951 C CA  . THR F 1 39  ? 4.268   -15.536 59.840 1.00 29.45  ? 241 THR F CA  1 
ATOM   14952 C C   . THR F 1 39  ? 4.507   -16.990 60.173 1.00 29.61  ? 241 THR F C   1 
ATOM   14953 O O   . THR F 1 39  ? 5.624   -17.397 60.456 1.00 29.91  ? 241 THR F O   1 
ATOM   14954 C CB  . THR F 1 39  ? 4.881   -15.223 58.467 1.00 26.60  ? 241 THR F CB  1 
ATOM   14955 O OG1 . THR F 1 39  ? 6.279   -15.514 58.493 1.00 27.82  ? 241 THR F OG1 1 
ATOM   14956 C CG2 . THR F 1 39  ? 4.680   -13.769 58.105 1.00 24.91  ? 241 THR F CG2 1 
ATOM   14957 N N   . THR F 1 40  ? 3.441   -17.773 60.113 1.00 31.52  ? 242 THR F N   1 
ATOM   14958 C CA  . THR F 1 40  ? 3.505   -19.188 60.406 1.00 33.23  ? 242 THR F CA  1 
ATOM   14959 C C   . THR F 1 40  ? 3.180   -19.955 59.147 1.00 31.69  ? 242 THR F C   1 
ATOM   14960 O O   . THR F 1 40  ? 2.236   -19.626 58.440 1.00 30.27  ? 242 THR F O   1 
ATOM   14961 C CB  . THR F 1 40  ? 2.498   -19.587 61.493 1.00 29.65  ? 242 THR F CB  1 
ATOM   14962 O OG1 . THR F 1 40  ? 2.666   -18.744 62.635 1.00 36.13  ? 242 THR F OG1 1 
ATOM   14963 C CG2 . THR F 1 40  ? 2.712   -21.026 61.906 1.00 31.80  ? 242 THR F CG2 1 
ATOM   14964 N N   . SER F 1 41  ? 3.988   -20.959 58.846 1.00 29.94  ? 243 SER F N   1 
ATOM   14965 C CA  . SER F 1 41  ? 3.759   -21.766 57.667 1.00 30.06  ? 243 SER F CA  1 
ATOM   14966 C C   . SER F 1 41  ? 3.837   -23.233 58.005 1.00 29.41  ? 243 SER F C   1 
ATOM   14967 O O   . SER F 1 41  ? 4.779   -23.680 58.638 1.00 30.36  ? 243 SER F O   1 
ATOM   14968 C CB  . SER F 1 41  ? 4.778   -21.439 56.580 1.00 26.91  ? 243 SER F CB  1 
ATOM   14969 O OG  . SER F 1 41  ? 4.350   -20.344 55.797 1.00 32.60  ? 243 SER F OG  1 
ATOM   14970 N N   . THR F 1 42  ? 2.824   -23.978 57.595 1.00 28.37  ? 244 THR F N   1 
ATOM   14971 C CA  . THR F 1 42  ? 2.809   -25.414 57.817 1.00 26.88  ? 244 THR F CA  1 
ATOM   14972 C C   . THR F 1 42  ? 2.671   -26.123 56.478 1.00 27.17  ? 244 THR F C   1 
ATOM   14973 O O   . THR F 1 42  ? 1.860   -25.727 55.637 1.00 28.94  ? 244 THR F O   1 
ATOM   14974 C CB  . THR F 1 42  ? 1.669   -25.824 58.756 1.00 28.79  ? 244 THR F CB  1 
ATOM   14975 O OG1 . THR F 1 42  ? 1.805   -25.130 60.000 1.00 28.63  ? 244 THR F OG1 1 
ATOM   14976 C CG2 . THR F 1 42  ? 1.719   -27.307 59.029 1.00 28.01  ? 244 THR F CG2 1 
ATOM   14977 N N   . ARG F 1 43  ? 3.484   -27.159 56.275 1.00 29.94  ? 245 ARG F N   1 
ATOM   14978 C CA  . ARG F 1 43  ? 3.449   -27.947 55.052 1.00 29.18  ? 245 ARG F CA  1 
ATOM   14979 C C   . ARG F 1 43  ? 3.462   -29.426 55.407 1.00 28.79  ? 245 ARG F C   1 
ATOM   14980 O O   . ARG F 1 43  ? 3.756   -29.813 56.539 1.00 28.99  ? 245 ARG F O   1 
ATOM   14981 C CB  . ARG F 1 43  ? 4.630   -27.625 54.133 1.00 20.15  ? 245 ARG F CB  1 
ATOM   14982 C CG  . ARG F 1 43  ? 4.740   -26.179 53.706 1.00 22.30  ? 245 ARG F CG  1 
ATOM   14983 C CD  . ARG F 1 43  ? 3.647   -25.780 52.746 1.00 23.18  ? 245 ARG F CD  1 
ATOM   14984 N NE  . ARG F 1 43  ? 3.838   -24.407 52.302 1.00 27.56  ? 245 ARG F NE  1 
ATOM   14985 C CZ  . ARG F 1 43  ? 3.348   -23.349 52.934 1.00 28.22  ? 245 ARG F CZ  1 
ATOM   14986 N NH1 . ARG F 1 43  ? 3.572   -22.131 52.470 1.00 29.12  ? 245 ARG F NH1 1 
ATOM   14987 N NH2 . ARG F 1 43  ? 2.638   -23.512 54.039 1.00 29.15  ? 245 ARG F NH2 1 
ATOM   14988 N N   . THR F 1 44  ? 3.140   -30.256 54.419 1.00 32.54  ? 246 THR F N   1 
ATOM   14989 C CA  . THR F 1 44  ? 3.198   -31.707 54.544 1.00 33.11  ? 246 THR F CA  1 
ATOM   14990 C C   . THR F 1 44  ? 4.363   -32.233 53.719 1.00 33.84  ? 246 THR F C   1 
ATOM   14991 O O   . THR F 1 44  ? 4.485   -31.910 52.534 1.00 33.82  ? 246 THR F O   1 
ATOM   14992 C CB  . THR F 1 44  ? 1.893   -32.359 54.083 1.00 34.32  ? 246 THR F CB  1 
ATOM   14993 O OG1 . THR F 1 44  ? 0.812   -31.912 54.908 1.00 35.82  ? 246 THR F OG1 1 
ATOM   14994 C CG2 . THR F 1 44  ? 1.997   -33.866 54.180 1.00 34.18  ? 246 THR F CG2 1 
ATOM   14995 N N   . TRP F 1 45  ? 5.203   -33.054 54.338 1.00 36.43  ? 247 TRP F N   1 
ATOM   14996 C CA  . TRP F 1 45  ? 6.434   -33.521 53.726 1.00 36.09  ? 247 TRP F CA  1 
ATOM   14997 C C   . TRP F 1 45  ? 6.437   -35.038 53.612 1.00 37.33  ? 247 TRP F C   1 
ATOM   14998 O O   . TRP F 1 45  ? 5.674   -35.737 54.282 1.00 37.05  ? 247 TRP F O   1 
ATOM   14999 C CB  . TRP F 1 45  ? 7.652   -33.072 54.533 1.00 36.90  ? 247 TRP F CB  1 
ATOM   15000 C CG  . TRP F 1 45  ? 7.600   -33.490 55.962 1.00 37.17  ? 247 TRP F CG  1 
ATOM   15001 C CD1 . TRP F 1 45  ? 7.063   -32.791 56.994 1.00 36.90  ? 247 TRP F CD1 1 
ATOM   15002 C CD2 . TRP F 1 45  ? 8.095   -34.713 56.520 1.00 37.30  ? 247 TRP F CD2 1 
ATOM   15003 N NE1 . TRP F 1 45  ? 7.198   -33.493 58.165 1.00 35.58  ? 247 TRP F NE1 1 
ATOM   15004 C CE2 . TRP F 1 45  ? 7.826   -34.680 57.899 1.00 35.94  ? 247 TRP F CE2 1 
ATOM   15005 C CE3 . TRP F 1 45  ? 8.738   -35.832 55.987 1.00 38.17  ? 247 TRP F CE3 1 
ATOM   15006 C CZ2 . TRP F 1 45  ? 8.180   -35.719 58.752 1.00 35.84  ? 247 TRP F CZ2 1 
ATOM   15007 C CZ3 . TRP F 1 45  ? 9.089   -36.859 56.834 1.00 37.64  ? 247 TRP F CZ3 1 
ATOM   15008 C CH2 . TRP F 1 45  ? 8.809   -36.797 58.201 1.00 36.52  ? 247 TRP F CH2 1 
ATOM   15009 N N   . ALA F 1 46  ? 7.308   -35.538 52.740 1.00 36.11  ? 248 ALA F N   1 
ATOM   15010 C CA  . ALA F 1 46  ? 7.550   -36.964 52.589 1.00 36.69  ? 248 ALA F CA  1 
ATOM   15011 C C   . ALA F 1 46  ? 9.045   -37.188 52.442 1.00 36.74  ? 248 ALA F C   1 
ATOM   15012 O O   . ALA F 1 46  ? 9.685   -36.567 51.589 1.00 37.29  ? 248 ALA F O   1 
ATOM   15013 C CB  . ALA F 1 46  ? 6.802   -37.530 51.383 1.00 40.01  ? 248 ALA F CB  1 
ATOM   15014 N N   . LEU F 1 47  ? 9.596   -38.072 53.267 1.00 40.49  ? 249 LEU F N   1 
ATOM   15015 C CA  . LEU F 1 47  ? 11.031  -38.324 53.300 1.00 39.91  ? 249 LEU F CA  1 
ATOM   15016 C C   . LEU F 1 47  ? 11.326  -39.748 52.851 1.00 40.75  ? 249 LEU F C   1 
ATOM   15017 O O   . LEU F 1 47  ? 10.994  -40.701 53.576 1.00 41.21  ? 249 LEU F O   1 
ATOM   15018 C CB  . LEU F 1 47  ? 11.585  -38.087 54.705 1.00 36.89  ? 249 LEU F CB  1 
ATOM   15019 C CG  . LEU F 1 47  ? 13.073  -38.361 54.881 1.00 36.18  ? 249 LEU F CG  1 
ATOM   15020 C CD1 . LEU F 1 47  ? 13.877  -37.417 54.015 1.00 36.18  ? 249 LEU F CD1 1 
ATOM   15021 C CD2 . LEU F 1 47  ? 13.468  -38.226 56.336 1.00 37.09  ? 249 LEU F CD2 1 
ATOM   15022 N N   . PRO F 1 48  ? 11.939  -39.949 51.695 1.00 41.20  ? 250 PRO F N   1 
ATOM   15023 C CA  . PRO F 1 48  ? 12.326  -41.294 51.266 1.00 42.02  ? 250 PRO F CA  1 
ATOM   15024 C C   . PRO F 1 48  ? 13.616  -41.728 51.950 1.00 43.20  ? 250 PRO F C   1 
ATOM   15025 O O   . PRO F 1 48  ? 14.130  -41.069 52.850 1.00 43.76  ? 250 PRO F O   1 
ATOM   15026 C CB  . PRO F 1 48  ? 12.530  -41.129 49.762 1.00 40.88  ? 250 PRO F CB  1 
ATOM   15027 C CG  . PRO F 1 48  ? 12.964  -39.725 49.617 1.00 39.86  ? 250 PRO F CG  1 
ATOM   15028 C CD  . PRO F 1 48  ? 12.220  -38.942 50.659 1.00 39.81  ? 250 PRO F CD  1 
ATOM   15029 N N   . THR F 1 49  ? 14.132  -42.867 51.504 1.00 45.80  ? 251 THR F N   1 
ATOM   15030 C CA  . THR F 1 49  ? 15.441  -43.341 51.923 1.00 46.13  ? 251 THR F CA  1 
ATOM   15031 C C   . THR F 1 49  ? 16.450  -43.042 50.825 1.00 46.25  ? 251 THR F C   1 
ATOM   15032 O O   . THR F 1 49  ? 16.323  -43.543 49.703 1.00 45.91  ? 251 THR F O   1 
ATOM   15033 C CB  . THR F 1 49  ? 15.411  -44.841 52.222 1.00 48.87  ? 251 THR F CB  1 
ATOM   15034 O OG1 . THR F 1 49  ? 14.490  -45.098 53.289 1.00 50.05  ? 251 THR F OG1 1 
ATOM   15035 C CG2 . THR F 1 49  ? 16.787  -45.326 52.632 1.00 47.28  ? 251 THR F CG2 1 
ATOM   15036 N N   . TYR F 1 50  ? 17.440  -42.215 51.144 1.00 43.88  ? 252 TYR F N   1 
ATOM   15037 C CA  . TYR F 1 50  ? 18.468  -41.823 50.191 1.00 44.87  ? 252 TYR F CA  1 
ATOM   15038 C C   . TYR F 1 50  ? 19.700  -42.699 50.358 1.00 46.19  ? 252 TYR F C   1 
ATOM   15039 O O   . TYR F 1 50  ? 20.055  -43.080 51.476 1.00 47.59  ? 252 TYR F O   1 
ATOM   15040 C CB  . TYR F 1 50  ? 18.858  -40.354 50.365 1.00 40.68  ? 252 TYR F CB  1 
ATOM   15041 C CG  . TYR F 1 50  ? 17.787  -39.357 49.993 1.00 39.20  ? 252 TYR F CG  1 
ATOM   15042 C CD1 . TYR F 1 50  ? 17.609  -38.966 48.675 1.00 39.01  ? 252 TYR F CD1 1 
ATOM   15043 C CD2 . TYR F 1 50  ? 16.984  -38.775 50.961 1.00 38.60  ? 252 TYR F CD2 1 
ATOM   15044 C CE1 . TYR F 1 50  ? 16.647  -38.048 48.329 1.00 37.99  ? 252 TYR F CE1 1 
ATOM   15045 C CE2 . TYR F 1 50  ? 16.018  -37.852 50.622 1.00 38.56  ? 252 TYR F CE2 1 
ATOM   15046 C CZ  . TYR F 1 50  ? 15.856  -37.494 49.305 1.00 38.75  ? 252 TYR F CZ  1 
ATOM   15047 O OH  . TYR F 1 50  ? 14.898  -36.575 48.959 1.00 40.77  ? 252 TYR F OH  1 
ATOM   15048 N N   . ASN F 1 51  ? 20.337  -43.028 49.235 1.00 46.46  ? 253 ASN F N   1 
ATOM   15049 C CA  . ASN F 1 51  ? 21.589  -43.783 49.193 1.00 48.31  ? 253 ASN F CA  1 
ATOM   15050 C C   . ASN F 1 51  ? 21.482  -45.153 49.850 1.00 49.62  ? 253 ASN F C   1 
ATOM   15051 O O   . ASN F 1 51  ? 22.505  -45.740 50.208 1.00 50.49  ? 253 ASN F O   1 
ATOM   15052 C CB  . ASN F 1 51  ? 22.742  -43.013 49.849 1.00 43.81  ? 253 ASN F CB  1 
ATOM   15053 C CG  . ASN F 1 51  ? 23.222  -41.845 49.022 1.00 44.32  ? 253 ASN F CG  1 
ATOM   15054 O OD1 . ASN F 1 51  ? 23.002  -41.786 47.814 1.00 45.89  ? 253 ASN F OD1 1 
ATOM   15055 N ND2 . ASN F 1 51  ? 23.920  -40.922 49.669 1.00 42.62  ? 253 ASN F ND2 1 
ATOM   15056 N N   . ASN F 1 52  ? 20.272  -45.695 49.989 1.00 48.06  ? 254 ASN F N   1 
ATOM   15057 C CA  . ASN F 1 52  ? 20.067  -46.993 50.635 1.00 50.33  ? 254 ASN F CA  1 
ATOM   15058 C C   . ASN F 1 52  ? 20.790  -47.072 51.977 1.00 49.82  ? 254 ASN F C   1 
ATOM   15059 O O   . ASN F 1 52  ? 21.527  -48.021 52.253 1.00 49.43  ? 254 ASN F O   1 
ATOM   15060 C CB  . ASN F 1 52  ? 20.507  -48.134 49.718 1.00 50.91  ? 254 ASN F CB  1 
ATOM   15061 C CG  . ASN F 1 52  ? 19.599  -48.301 48.522 1.00 56.48  ? 254 ASN F CG  1 
ATOM   15062 O OD1 . ASN F 1 52  ? 18.510  -48.862 48.630 1.00 59.84  ? 254 ASN F OD1 1 
ATOM   15063 N ND2 . ASN F 1 52  ? 20.042  -47.813 47.370 1.00 59.08  ? 254 ASN F ND2 1 
ATOM   15064 N N   . HIS F 1 53  ? 20.591  -46.051 52.811 1.00 47.67  ? 255 HIS F N   1 
ATOM   15065 C CA  . HIS F 1 53  ? 21.161  -45.958 54.154 1.00 47.73  ? 255 HIS F CA  1 
ATOM   15066 C C   . HIS F 1 53  ? 22.683  -45.884 54.155 1.00 46.51  ? 255 HIS F C   1 
ATOM   15067 O O   . HIS F 1 53  ? 23.317  -46.279 55.136 1.00 47.91  ? 255 HIS F O   1 
ATOM   15068 C CB  . HIS F 1 53  ? 20.713  -47.132 55.034 1.00 51.59  ? 255 HIS F CB  1 
ATOM   15069 C CG  . HIS F 1 53  ? 19.230  -47.253 55.175 1.00 54.81  ? 255 HIS F CG  1 
ATOM   15070 N ND1 . HIS F 1 53  ? 18.476  -46.365 55.910 1.00 57.62  ? 255 HIS F ND1 1 
ATOM   15071 C CD2 . HIS F 1 53  ? 18.360  -48.158 54.668 1.00 54.34  ? 255 HIS F CD2 1 
ATOM   15072 C CE1 . HIS F 1 53  ? 17.205  -46.720 55.854 1.00 57.94  ? 255 HIS F CE1 1 
ATOM   15073 N NE2 . HIS F 1 53  ? 17.107  -47.804 55.107 1.00 56.53  ? 255 HIS F NE2 1 
ATOM   15074 N N   . LEU F 1 54  ? 23.296  -45.376 53.091 1.00 46.87  ? 256 LEU F N   1 
ATOM   15075 C CA  . LEU F 1 54  ? 24.744  -45.399 52.956 1.00 43.47  ? 256 LEU F CA  1 
ATOM   15076 C C   . LEU F 1 54  ? 25.315  -44.000 52.777 1.00 43.43  ? 256 LEU F C   1 
ATOM   15077 O O   . LEU F 1 54  ? 24.624  -43.071 52.352 1.00 44.42  ? 256 LEU F O   1 
ATOM   15078 C CB  . LEU F 1 54  ? 25.174  -46.262 51.767 1.00 43.01  ? 256 LEU F CB  1 
ATOM   15079 C CG  . LEU F 1 54  ? 24.885  -47.758 51.832 1.00 40.47  ? 256 LEU F CG  1 
ATOM   15080 C CD1 . LEU F 1 54  ? 25.253  -48.411 50.516 1.00 38.80  ? 256 LEU F CD1 1 
ATOM   15081 C CD2 . LEU F 1 54  ? 25.650  -48.386 52.979 1.00 39.34  ? 256 LEU F CD2 1 
ATOM   15082 N N   . TYR F 1 55  ? 26.593  -43.867 53.118 1.00 42.77  ? 257 TYR F N   1 
ATOM   15083 C CA  . TYR F 1 55  ? 27.393  -42.729 52.696 1.00 42.20  ? 257 TYR F CA  1 
ATOM   15084 C C   . TYR F 1 55  ? 28.159  -43.104 51.437 1.00 42.30  ? 257 TYR F C   1 
ATOM   15085 O O   . TYR F 1 55  ? 28.793  -44.159 51.376 1.00 43.56  ? 257 TYR F O   1 
ATOM   15086 C CB  . TYR F 1 55  ? 28.372  -42.322 53.793 1.00 43.62  ? 257 TYR F CB  1 
ATOM   15087 C CG  . TYR F 1 55  ? 27.712  -41.816 55.048 1.00 44.56  ? 257 TYR F CG  1 
ATOM   15088 C CD1 . TYR F 1 55  ? 27.457  -40.465 55.224 1.00 44.58  ? 257 TYR F CD1 1 
ATOM   15089 C CD2 . TYR F 1 55  ? 27.326  -42.691 56.051 1.00 44.55  ? 257 TYR F CD2 1 
ATOM   15090 C CE1 . TYR F 1 55  ? 26.849  -40.000 56.369 1.00 45.68  ? 257 TYR F CE1 1 
ATOM   15091 C CE2 . TYR F 1 55  ? 26.715  -42.235 57.197 1.00 46.24  ? 257 TYR F CE2 1 
ATOM   15092 C CZ  . TYR F 1 55  ? 26.480  -40.890 57.351 1.00 46.81  ? 257 TYR F CZ  1 
ATOM   15093 O OH  . TYR F 1 55  ? 25.870  -40.437 58.495 1.00 49.05  ? 257 TYR F OH  1 
ATOM   15094 N N   . LYS F 1 56  ? 28.094  -42.246 50.425 1.00 39.43  ? 258 LYS F N   1 
ATOM   15095 C CA  . LYS F 1 56  ? 28.775  -42.539 49.174 1.00 39.29  ? 258 LYS F CA  1 
ATOM   15096 C C   . LYS F 1 56  ? 29.605  -41.346 48.731 1.00 38.63  ? 258 LYS F C   1 
ATOM   15097 O O   . LYS F 1 56  ? 29.072  -40.259 48.491 1.00 39.41  ? 258 LYS F O   1 
ATOM   15098 C CB  . LYS F 1 56  ? 27.780  -42.940 48.078 1.00 38.01  ? 258 LYS F CB  1 
ATOM   15099 C CG  . LYS F 1 56  ? 27.138  -44.296 48.328 1.00 41.46  ? 258 LYS F CG  1 
ATOM   15100 C CD  . LYS F 1 56  ? 26.380  -44.812 47.120 1.00 42.45  ? 258 LYS F CD  1 
ATOM   15101 C CE  . LYS F 1 56  ? 25.168  -43.959 46.809 1.00 44.51  ? 258 LYS F CE  1 
ATOM   15102 N NZ  . LYS F 1 56  ? 24.368  -44.535 45.696 1.00 47.34  ? 258 LYS F NZ  1 
ATOM   15103 N N   . GLN F 1 57  ? 30.913  -41.563 48.640 1.00 40.57  ? 259 GLN F N   1 
ATOM   15104 C CA  . GLN F 1 57  ? 31.817  -40.609 48.013 1.00 40.33  ? 259 GLN F CA  1 
ATOM   15105 C C   . GLN F 1 57  ? 31.402  -40.313 46.577 1.00 40.92  ? 259 GLN F C   1 
ATOM   15106 O O   . GLN F 1 57  ? 31.144  -41.228 45.790 1.00 41.07  ? 259 GLN F O   1 
ATOM   15107 C CB  . GLN F 1 57  ? 33.233  -41.169 48.036 1.00 39.06  ? 259 GLN F CB  1 
ATOM   15108 C CG  . GLN F 1 57  ? 34.254  -40.375 47.258 1.00 39.81  ? 259 GLN F CG  1 
ATOM   15109 C CD  . GLN F 1 57  ? 35.630  -40.974 47.376 1.00 42.14  ? 259 GLN F CD  1 
ATOM   15110 O OE1 . GLN F 1 57  ? 35.879  -41.805 48.242 1.00 45.76  ? 259 GLN F OE1 1 
ATOM   15111 N NE2 . GLN F 1 57  ? 36.506  -40.620 46.465 1.00 40.51  ? 259 GLN F NE2 1 
ATOM   15112 N N   . ILE F 1 58  ? 31.355  -39.029 46.231 1.00 41.32  ? 260 ILE F N   1 
ATOM   15113 C CA  . ILE F 1 58  ? 31.058  -38.590 44.876 1.00 42.11  ? 260 ILE F CA  1 
ATOM   15114 C C   . ILE F 1 58  ? 32.181  -37.684 44.396 1.00 45.03  ? 260 ILE F C   1 
ATOM   15115 O O   . ILE F 1 58  ? 32.881  -37.053 45.194 1.00 45.80  ? 260 ILE F O   1 
ATOM   15116 C CB  . ILE F 1 58  ? 29.700  -37.865 44.786 1.00 41.05  ? 260 ILE F CB  1 
ATOM   15117 C CG1 . ILE F 1 58  ? 29.706  -36.618 45.666 1.00 40.01  ? 260 ILE F CG1 1 
ATOM   15118 C CG2 . ILE F 1 58  ? 28.574  -38.793 45.192 1.00 37.86  ? 260 ILE F CG2 1 
ATOM   15119 C CD1 . ILE F 1 58  ? 28.490  -35.751 45.481 1.00 39.42  ? 260 ILE F CD1 1 
ATOM   15120 N N   . SER F 1 59  ? 32.352  -37.624 43.078 1.00 48.58  ? 261 SER F N   1 
ATOM   15121 C CA  . SER F 1 59  ? 33.401  -36.814 42.473 1.00 50.97  ? 261 SER F CA  1 
ATOM   15122 C C   . SER F 1 59  ? 32.999  -36.489 41.040 1.00 53.59  ? 261 SER F C   1 
ATOM   15123 O O   . SER F 1 59  ? 31.962  -36.937 40.547 1.00 53.47  ? 261 SER F O   1 
ATOM   15124 C CB  . SER F 1 59  ? 34.751  -37.531 42.525 1.00 53.63  ? 261 SER F CB  1 
ATOM   15125 O OG  . SER F 1 59  ? 34.723  -38.722 41.758 1.00 52.74  ? 261 SER F OG  1 
ATOM   15126 N N   . ASN F 1 60  ? 33.846  -35.711 40.368 1.00 53.57  ? 262 ASN F N   1 
ATOM   15127 C CA  . ASN F 1 60  ? 33.538  -35.248 39.020 1.00 56.97  ? 262 ASN F CA  1 
ATOM   15128 C C   . ASN F 1 60  ? 33.820  -36.327 37.982 1.00 59.85  ? 262 ASN F C   1 
ATOM   15129 O O   . ASN F 1 60  ? 33.136  -36.408 36.956 1.00 60.18  ? 262 ASN F O   1 
ATOM   15130 C CB  . ASN F 1 60  ? 34.338  -33.976 38.723 1.00 55.70  ? 262 ASN F CB  1 
ATOM   15131 C CG  . ASN F 1 60  ? 35.841  -34.214 38.697 1.00 55.19  ? 262 ASN F CG  1 
ATOM   15132 O OD1 . ASN F 1 60  ? 36.325  -35.183 38.119 1.00 54.73  ? 262 ASN F OD1 1 
ATOM   15133 N ND2 . ASN F 1 60  ? 36.581  -33.351 39.372 1.00 55.24  ? 262 ASN F ND2 1 
ATOM   15134 N N   . SER F 1 61  ? 34.840  -37.153 38.232 1.00 60.98  ? 263 SER F N   1 
ATOM   15135 C CA  . SER F 1 61  ? 35.232  -38.178 37.271 1.00 64.61  ? 263 SER F CA  1 
ATOM   15136 C C   . SER F 1 61  ? 34.145  -39.229 37.094 1.00 66.76  ? 263 SER F C   1 
ATOM   15137 O O   . SER F 1 61  ? 34.129  -39.933 36.078 1.00 67.37  ? 263 SER F O   1 
ATOM   15138 C CB  . SER F 1 61  ? 36.542  -38.832 37.708 1.00 67.62  ? 263 SER F CB  1 
ATOM   15139 O OG  . SER F 1 61  ? 36.934  -39.851 36.806 1.00 69.00  ? 263 SER F OG  1 
ATOM   15140 N N   . THR F 1 62  ? 33.241  -39.360 38.069 1.00 64.53  ? 264 THR F N   1 
ATOM   15141 C CA  . THR F 1 62  ? 32.079  -40.220 37.878 1.00 66.15  ? 264 THR F CA  1 
ATOM   15142 C C   . THR F 1 62  ? 31.216  -39.727 36.725 1.00 67.93  ? 264 THR F C   1 
ATOM   15143 O O   . THR F 1 62  ? 30.641  -40.534 35.987 1.00 67.56  ? 264 THR F O   1 
ATOM   15144 C CB  . THR F 1 62  ? 31.254  -40.292 39.162 1.00 61.59  ? 264 THR F CB  1 
ATOM   15145 O OG1 . THR F 1 62  ? 30.805  -38.978 39.516 1.00 60.31  ? 264 THR F OG1 1 
ATOM   15146 C CG2 . THR F 1 62  ? 32.088  -40.856 40.299 1.00 61.06  ? 264 THR F CG2 1 
ATOM   15147 N N   . SER F 1 63  ? 31.118  -38.410 36.554 1.00 66.96  ? 265 SER F N   1 
ATOM   15148 C CA  . SER F 1 63  ? 30.412  -37.816 35.428 1.00 68.75  ? 265 SER F CA  1 
ATOM   15149 C C   . SER F 1 63  ? 31.337  -37.476 34.265 1.00 70.30  ? 265 SER F C   1 
ATOM   15150 O O   . SER F 1 63  ? 30.874  -36.911 33.269 1.00 70.70  ? 265 SER F O   1 
ATOM   15151 C CB  . SER F 1 63  ? 29.662  -36.564 35.885 1.00 67.70  ? 265 SER F CB  1 
ATOM   15152 O OG  . SER F 1 63  ? 28.664  -36.894 36.835 1.00 69.32  ? 265 SER F OG  1 
ATOM   15153 N N   . GLY F 1 64  ? 32.624  -37.802 34.370 1.00 70.08  ? 266 GLY F N   1 
ATOM   15154 C CA  . GLY F 1 64  ? 33.587  -37.622 33.304 1.00 71.35  ? 266 GLY F CA  1 
ATOM   15155 C C   . GLY F 1 64  ? 34.508  -36.431 33.470 1.00 72.22  ? 266 GLY F C   1 
ATOM   15156 O O   . GLY F 1 64  ? 35.617  -36.449 32.921 1.00 72.88  ? 266 GLY F O   1 
ATOM   15157 N N   . GLY F 1 65  ? 34.089  -35.407 34.216 1.00 71.57  ? 267 GLY F N   1 
ATOM   15158 C CA  . GLY F 1 65  ? 34.949  -34.296 34.591 1.00 70.43  ? 267 GLY F CA  1 
ATOM   15159 C C   . GLY F 1 65  ? 35.775  -33.683 33.477 1.00 69.41  ? 267 GLY F C   1 
ATOM   15160 O O   . GLY F 1 65  ? 36.979  -33.467 33.643 1.00 68.90  ? 267 GLY F O   1 
ATOM   15161 N N   . SER F 1 66  ? 35.146  -33.392 32.338 1.00 71.77  ? 268 SER F N   1 
ATOM   15162 C CA  . SER F 1 66  ? 35.896  -32.913 31.182 1.00 70.03  ? 268 SER F CA  1 
ATOM   15163 C C   . SER F 1 66  ? 36.381  -31.478 31.349 1.00 68.39  ? 268 SER F C   1 
ATOM   15164 O O   . SER F 1 66  ? 37.137  -30.986 30.504 1.00 67.77  ? 268 SER F O   1 
ATOM   15165 C CB  . SER F 1 66  ? 35.042  -33.028 29.918 1.00 72.00  ? 268 SER F CB  1 
ATOM   15166 O OG  . SER F 1 66  ? 34.752  -34.383 29.622 1.00 71.59  ? 268 SER F OG  1 
ATOM   15167 N N   . SER F 1 67  ? 35.970  -30.796 32.414 1.00 66.15  ? 269 SER F N   1 
ATOM   15168 C CA  . SER F 1 67  ? 36.324  -29.400 32.639 1.00 63.34  ? 269 SER F CA  1 
ATOM   15169 C C   . SER F 1 67  ? 37.002  -29.261 33.995 1.00 61.64  ? 269 SER F C   1 
ATOM   15170 O O   . SER F 1 67  ? 36.599  -29.913 34.965 1.00 60.68  ? 269 SER F O   1 
ATOM   15171 C CB  . SER F 1 67  ? 35.085  -28.508 32.563 1.00 60.82  ? 269 SER F CB  1 
ATOM   15172 O OG  . SER F 1 67  ? 35.417  -27.157 32.824 1.00 59.42  ? 269 SER F OG  1 
ATOM   15173 N N   . ASN F 1 68  ? 38.031  -28.412 34.058 1.00 58.94  ? 270 ASN F N   1 
ATOM   15174 C CA  . ASN F 1 68  ? 38.704  -28.160 35.328 1.00 57.20  ? 270 ASN F CA  1 
ATOM   15175 C C   . ASN F 1 68  ? 37.912  -27.203 36.205 1.00 55.06  ? 270 ASN F C   1 
ATOM   15176 O O   . ASN F 1 68  ? 37.985  -27.286 37.436 1.00 54.08  ? 270 ASN F O   1 
ATOM   15177 C CB  . ASN F 1 68  ? 40.106  -27.606 35.085 1.00 57.76  ? 270 ASN F CB  1 
ATOM   15178 C CG  . ASN F 1 68  ? 40.921  -27.514 36.360 1.00 59.45  ? 270 ASN F CG  1 
ATOM   15179 O OD1 . ASN F 1 68  ? 40.744  -28.309 37.283 1.00 58.95  ? 270 ASN F OD1 1 
ATOM   15180 N ND2 . ASN F 1 68  ? 41.817  -26.536 36.421 1.00 59.72  ? 270 ASN F ND2 1 
ATOM   15181 N N   . ASP F 1 69  ? 37.162  -26.281 35.598 1.00 53.23  ? 271 ASP F N   1 
ATOM   15182 C CA  . ASP F 1 69  ? 36.352  -25.361 36.388 1.00 50.86  ? 271 ASP F CA  1 
ATOM   15183 C C   . ASP F 1 69  ? 35.246  -26.091 37.134 1.00 48.48  ? 271 ASP F C   1 
ATOM   15184 O O   . ASP F 1 69  ? 34.813  -25.639 38.199 1.00 48.32  ? 271 ASP F O   1 
ATOM   15185 C CB  . ASP F 1 69  ? 35.758  -24.280 35.487 1.00 46.25  ? 271 ASP F CB  1 
ATOM   15186 C CG  . ASP F 1 69  ? 36.797  -23.298 34.992 1.00 48.76  ? 271 ASP F CG  1 
ATOM   15187 O OD1 . ASP F 1 69  ? 37.895  -23.240 35.584 1.00 49.50  ? 271 ASP F OD1 1 
ATOM   15188 O OD2 . ASP F 1 69  ? 36.515  -22.587 34.006 1.00 49.62  ? 271 ASP F OD2 1 
ATOM   15189 N N   . ASN F 1 70  ? 34.783  -27.217 36.599 1.00 48.95  ? 272 ASN F N   1 
ATOM   15190 C CA  . ASN F 1 70  ? 33.679  -27.971 37.173 1.00 46.49  ? 272 ASN F CA  1 
ATOM   15191 C C   . ASN F 1 70  ? 34.129  -29.096 38.093 1.00 44.47  ? 272 ASN F C   1 
ATOM   15192 O O   . ASN F 1 70  ? 33.287  -29.872 38.550 1.00 44.45  ? 272 ASN F O   1 
ATOM   15193 C CB  . ASN F 1 70  ? 32.802  -28.538 36.056 1.00 45.18  ? 272 ASN F CB  1 
ATOM   15194 C CG  . ASN F 1 70  ? 32.036  -27.462 35.319 1.00 45.50  ? 272 ASN F CG  1 
ATOM   15195 O OD1 . ASN F 1 70  ? 31.775  -26.391 35.862 1.00 46.83  ? 272 ASN F OD1 1 
ATOM   15196 N ND2 . ASN F 1 70  ? 31.680  -27.738 34.073 1.00 46.45  ? 272 ASN F ND2 1 
ATOM   15197 N N   . ALA F 1 71  ? 35.425  -29.215 38.361 1.00 50.48  ? 273 ALA F N   1 
ATOM   15198 C CA  . ALA F 1 71  ? 35.927  -30.280 39.218 1.00 47.70  ? 273 ALA F CA  1 
ATOM   15199 C C   . ALA F 1 71  ? 35.435  -30.112 40.652 1.00 46.27  ? 273 ALA F C   1 
ATOM   15200 O O   . ALA F 1 71  ? 35.367  -29.001 41.181 1.00 46.63  ? 273 ALA F O   1 
ATOM   15201 C CB  . ALA F 1 71  ? 37.455  -30.299 39.193 1.00 47.18  ? 273 ALA F CB  1 
ATOM   15202 N N   . TYR F 1 72  ? 35.088  -31.234 41.285 1.00 47.37  ? 274 TYR F N   1 
ATOM   15203 C CA  . TYR F 1 72  ? 34.636  -31.210 42.670 1.00 45.27  ? 274 TYR F CA  1 
ATOM   15204 C C   . TYR F 1 72  ? 34.860  -32.578 43.298 1.00 43.73  ? 274 TYR F C   1 
ATOM   15205 O O   . TYR F 1 72  ? 34.991  -33.586 42.601 1.00 43.20  ? 274 TYR F O   1 
ATOM   15206 C CB  . TYR F 1 72  ? 33.166  -30.797 42.770 1.00 43.70  ? 274 TYR F CB  1 
ATOM   15207 C CG  . TYR F 1 72  ? 32.196  -31.773 42.149 1.00 44.19  ? 274 TYR F CG  1 
ATOM   15208 C CD1 . TYR F 1 72  ? 31.607  -32.769 42.911 1.00 45.12  ? 274 TYR F CD1 1 
ATOM   15209 C CD2 . TYR F 1 72  ? 31.870  -31.702 40.801 1.00 44.52  ? 274 TYR F CD2 1 
ATOM   15210 C CE1 . TYR F 1 72  ? 30.720  -33.658 42.359 1.00 45.68  ? 274 TYR F CE1 1 
ATOM   15211 C CE2 . TYR F 1 72  ? 30.979  -32.590 40.239 1.00 45.13  ? 274 TYR F CE2 1 
ATOM   15212 C CZ  . TYR F 1 72  ? 30.410  -33.566 41.024 1.00 45.75  ? 274 TYR F CZ  1 
ATOM   15213 O OH  . TYR F 1 72  ? 29.525  -34.458 40.474 1.00 46.01  ? 274 TYR F OH  1 
ATOM   15214 N N   . PHE F 1 73  ? 34.917  -32.592 44.630 1.00 43.09  ? 275 PHE F N   1 
ATOM   15215 C CA  . PHE F 1 73  ? 35.041  -33.810 45.418 1.00 42.40  ? 275 PHE F CA  1 
ATOM   15216 C C   . PHE F 1 73  ? 34.262  -33.643 46.714 1.00 42.71  ? 275 PHE F C   1 
ATOM   15217 O O   . PHE F 1 73  ? 34.367  -32.608 47.376 1.00 43.22  ? 275 PHE F O   1 
ATOM   15218 C CB  . PHE F 1 73  ? 36.511  -34.121 45.730 1.00 44.47  ? 275 PHE F CB  1 
ATOM   15219 C CG  . PHE F 1 73  ? 36.706  -35.304 46.628 1.00 44.27  ? 275 PHE F CG  1 
ATOM   15220 C CD1 . PHE F 1 73  ? 36.770  -36.571 46.104 1.00 44.55  ? 275 PHE F CD1 1 
ATOM   15221 C CD2 . PHE F 1 73  ? 36.809  -35.145 47.998 1.00 44.54  ? 275 PHE F CD2 1 
ATOM   15222 C CE1 . PHE F 1 73  ? 36.951  -37.657 46.929 1.00 44.29  ? 275 PHE F CE1 1 
ATOM   15223 C CE2 . PHE F 1 73  ? 36.970  -36.221 48.823 1.00 44.88  ? 275 PHE F CE2 1 
ATOM   15224 C CZ  . PHE F 1 73  ? 37.044  -37.481 48.290 1.00 45.14  ? 275 PHE F CZ  1 
ATOM   15225 N N   . GLY F 1 74  ? 33.508  -34.668 47.088 1.00 42.60  ? 276 GLY F N   1 
ATOM   15226 C CA  . GLY F 1 74  ? 32.725  -34.592 48.306 1.00 41.90  ? 276 GLY F CA  1 
ATOM   15227 C C   . GLY F 1 74  ? 32.054  -35.907 48.625 1.00 42.40  ? 276 GLY F C   1 
ATOM   15228 O O   . GLY F 1 74  ? 32.419  -36.954 48.088 1.00 43.39  ? 276 GLY F O   1 
ATOM   15229 N N   . TYR F 1 75  ? 31.053  -35.840 49.503 1.00 38.86  ? 277 TYR F N   1 
ATOM   15230 C CA  . TYR F 1 75  ? 30.325  -37.015 49.957 1.00 38.43  ? 277 TYR F CA  1 
ATOM   15231 C C   . TYR F 1 75  ? 28.829  -36.751 49.906 1.00 38.74  ? 277 TYR F C   1 
ATOM   15232 O O   . TYR F 1 75  ? 28.389  -35.605 50.021 1.00 39.14  ? 277 TYR F O   1 
ATOM   15233 C CB  . TYR F 1 75  ? 30.734  -37.403 51.380 1.00 41.09  ? 277 TYR F CB  1 
ATOM   15234 C CG  . TYR F 1 75  ? 32.184  -37.798 51.493 1.00 41.51  ? 277 TYR F CG  1 
ATOM   15235 C CD1 . TYR F 1 75  ? 32.590  -39.099 51.239 1.00 42.73  ? 277 TYR F CD1 1 
ATOM   15236 C CD2 . TYR F 1 75  ? 33.149  -36.868 51.846 1.00 40.69  ? 277 TYR F CD2 1 
ATOM   15237 C CE1 . TYR F 1 75  ? 33.915  -39.461 51.335 1.00 44.71  ? 277 TYR F CE1 1 
ATOM   15238 C CE2 . TYR F 1 75  ? 34.474  -37.222 51.945 1.00 42.25  ? 277 TYR F CE2 1 
ATOM   15239 C CZ  . TYR F 1 75  ? 34.851  -38.519 51.689 1.00 44.29  ? 277 TYR F CZ  1 
ATOM   15240 O OH  . TYR F 1 75  ? 36.171  -38.879 51.786 1.00 46.35  ? 277 TYR F OH  1 
ATOM   15241 N N   . SER F 1 76  ? 28.056  -37.818 49.732 1.00 38.23  ? 278 SER F N   1 
ATOM   15242 C CA  . SER F 1 76  ? 26.603  -37.760 49.739 1.00 39.06  ? 278 SER F CA  1 
ATOM   15243 C C   . SER F 1 76  ? 26.063  -38.641 50.856 1.00 39.48  ? 278 SER F C   1 
ATOM   15244 O O   . SER F 1 76  ? 26.472  -39.796 51.003 1.00 39.80  ? 278 SER F O   1 
ATOM   15245 C CB  . SER F 1 76  ? 26.027  -38.204 48.397 1.00 38.87  ? 278 SER F CB  1 
ATOM   15246 O OG  . SER F 1 76  ? 26.348  -39.555 48.128 1.00 40.56  ? 278 SER F OG  1 
ATOM   15247 N N   . THR F 1 77  ? 25.133  -38.096 51.625 1.00 39.84  ? 279 THR F N   1 
ATOM   15248 C CA  . THR F 1 77  ? 24.671  -38.693 52.864 1.00 39.53  ? 279 THR F CA  1 
ATOM   15249 C C   . THR F 1 77  ? 23.215  -39.123 52.739 1.00 39.64  ? 279 THR F C   1 
ATOM   15250 O O   . THR F 1 77  ? 22.459  -38.562 51.937 1.00 40.99  ? 279 THR F O   1 
ATOM   15251 C CB  . THR F 1 77  ? 24.819  -37.696 54.021 1.00 38.64  ? 279 THR F CB  1 
ATOM   15252 O OG1 . THR F 1 77  ? 24.013  -36.544 53.760 1.00 38.60  ? 279 THR F OG1 1 
ATOM   15253 C CG2 . THR F 1 77  ? 26.260  -37.250 54.152 1.00 36.12  ? 279 THR F CG2 1 
ATOM   15254 N N   . PRO F 1 78  ? 22.786  -40.126 53.514 1.00 40.04  ? 280 PRO F N   1 
ATOM   15255 C CA  . PRO F 1 78  ? 21.380  -40.552 53.455 1.00 39.88  ? 280 PRO F CA  1 
ATOM   15256 C C   . PRO F 1 78  ? 20.411  -39.520 53.995 1.00 40.06  ? 280 PRO F C   1 
ATOM   15257 O O   . PRO F 1 78  ? 19.204  -39.643 53.757 1.00 41.86  ? 280 PRO F O   1 
ATOM   15258 C CB  . PRO F 1 78  ? 21.367  -41.819 54.314 1.00 38.71  ? 280 PRO F CB  1 
ATOM   15259 C CG  . PRO F 1 78  ? 22.477  -41.614 55.280 1.00 38.43  ? 280 PRO F CG  1 
ATOM   15260 C CD  . PRO F 1 78  ? 23.547  -40.896 54.514 1.00 38.80  ? 280 PRO F CD  1 
ATOM   15261 N N   . TRP F 1 79  ? 20.901  -38.519 54.715 1.00 34.68  ? 281 TRP F N   1 
ATOM   15262 C CA  . TRP F 1 79  ? 20.062  -37.559 55.412 1.00 34.14  ? 281 TRP F CA  1 
ATOM   15263 C C   . TRP F 1 79  ? 19.401  -36.580 54.449 1.00 34.52  ? 281 TRP F C   1 
ATOM   15264 O O   . TRP F 1 79  ? 19.908  -36.301 53.360 1.00 35.28  ? 281 TRP F O   1 
ATOM   15265 C CB  . TRP F 1 79  ? 20.905  -36.797 56.429 1.00 35.45  ? 281 TRP F CB  1 
ATOM   15266 C CG  . TRP F 1 79  ? 21.355  -37.636 57.580 1.00 36.39  ? 281 TRP F CG  1 
ATOM   15267 C CD1 . TRP F 1 79  ? 22.439  -38.458 57.617 1.00 37.12  ? 281 TRP F CD1 1 
ATOM   15268 C CD2 . TRP F 1 79  ? 20.775  -37.681 58.885 1.00 37.13  ? 281 TRP F CD2 1 
ATOM   15269 N NE1 . TRP F 1 79  ? 22.549  -39.042 58.851 1.00 37.67  ? 281 TRP F NE1 1 
ATOM   15270 C CE2 . TRP F 1 79  ? 21.541  -38.577 59.651 1.00 36.80  ? 281 TRP F CE2 1 
ATOM   15271 C CE3 . TRP F 1 79  ? 19.674  -37.060 59.476 1.00 37.81  ? 281 TRP F CE3 1 
ATOM   15272 C CZ2 . TRP F 1 79  ? 21.243  -38.868 60.975 1.00 36.76  ? 281 TRP F CZ2 1 
ATOM   15273 C CZ3 . TRP F 1 79  ? 19.379  -37.350 60.789 1.00 38.41  ? 281 TRP F CZ3 1 
ATOM   15274 C CH2 . TRP F 1 79  ? 20.160  -38.245 61.526 1.00 38.57  ? 281 TRP F CH2 1 
ATOM   15275 N N   . GLY F 1 80  ? 18.242  -36.068 54.863 1.00 33.55  ? 282 GLY F N   1 
ATOM   15276 C CA  . GLY F 1 80  ? 17.601  -34.947 54.217 1.00 33.74  ? 282 GLY F CA  1 
ATOM   15277 C C   . GLY F 1 80  ? 17.726  -33.693 55.070 1.00 34.41  ? 282 GLY F C   1 
ATOM   15278 O O   . GLY F 1 80  ? 18.291  -33.704 56.161 1.00 33.91  ? 282 GLY F O   1 
ATOM   15279 N N   . TYR F 1 81  ? 17.185  -32.594 54.551 1.00 31.71  ? 283 TYR F N   1 
ATOM   15280 C CA  . TYR F 1 81  ? 17.193  -31.351 55.307 1.00 32.05  ? 283 TYR F CA  1 
ATOM   15281 C C   . TYR F 1 81  ? 15.988  -30.504 54.928 1.00 33.31  ? 283 TYR F C   1 
ATOM   15282 O O   . TYR F 1 81  ? 15.535  -30.518 53.782 1.00 33.46  ? 283 TYR F O   1 
ATOM   15283 C CB  . TYR F 1 81  ? 18.491  -30.563 55.085 1.00 33.22  ? 283 TYR F CB  1 
ATOM   15284 C CG  . TYR F 1 81  ? 18.726  -30.114 53.660 1.00 34.21  ? 283 TYR F CG  1 
ATOM   15285 C CD1 . TYR F 1 81  ? 18.248  -28.893 53.206 1.00 34.88  ? 283 TYR F CD1 1 
ATOM   15286 C CD2 . TYR F 1 81  ? 19.440  -30.902 52.775 1.00 34.75  ? 283 TYR F CD2 1 
ATOM   15287 C CE1 . TYR F 1 81  ? 18.463  -28.480 51.911 1.00 36.21  ? 283 TYR F CE1 1 
ATOM   15288 C CE2 . TYR F 1 81  ? 19.661  -30.494 51.479 1.00 35.93  ? 283 TYR F CE2 1 
ATOM   15289 C CZ  . TYR F 1 81  ? 19.172  -29.282 51.053 1.00 36.35  ? 283 TYR F CZ  1 
ATOM   15290 O OH  . TYR F 1 81  ? 19.389  -28.869 49.762 1.00 35.84  ? 283 TYR F OH  1 
ATOM   15291 N N   . PHE F 1 82  ? 15.480  -29.763 55.909 1.00 31.67  ? 284 PHE F N   1 
ATOM   15292 C CA  . PHE F 1 82  ? 14.421  -28.791 55.685 1.00 33.12  ? 284 PHE F CA  1 
ATOM   15293 C C   . PHE F 1 82  ? 15.032  -27.439 55.354 1.00 36.13  ? 284 PHE F C   1 
ATOM   15294 O O   . PHE F 1 82  ? 15.921  -26.959 56.063 1.00 37.28  ? 284 PHE F O   1 
ATOM   15295 C CB  . PHE F 1 82  ? 13.531  -28.650 56.920 1.00 33.22  ? 284 PHE F CB  1 
ATOM   15296 C CG  . PHE F 1 82  ? 12.803  -29.902 57.294 1.00 33.78  ? 284 PHE F CG  1 
ATOM   15297 C CD1 . PHE F 1 82  ? 11.630  -30.254 56.655 1.00 33.11  ? 284 PHE F CD1 1 
ATOM   15298 C CD2 . PHE F 1 82  ? 13.279  -30.715 58.302 1.00 34.35  ? 284 PHE F CD2 1 
ATOM   15299 C CE1 . PHE F 1 82  ? 10.959  -31.400 57.003 1.00 33.85  ? 284 PHE F CE1 1 
ATOM   15300 C CE2 . PHE F 1 82  ? 12.610  -31.862 58.655 1.00 34.63  ? 284 PHE F CE2 1 
ATOM   15301 C CZ  . PHE F 1 82  ? 11.446  -32.205 58.006 1.00 34.63  ? 284 PHE F CZ  1 
ATOM   15302 N N   . ASP F 1 83  ? 14.553  -26.823 54.278 1.00 32.88  ? 285 ASP F N   1 
ATOM   15303 C CA  . ASP F 1 83  ? 15.038  -25.510 53.868 1.00 34.55  ? 285 ASP F CA  1 
ATOM   15304 C C   . ASP F 1 83  ? 13.843  -24.586 53.667 1.00 32.07  ? 285 ASP F C   1 
ATOM   15305 O O   . ASP F 1 83  ? 13.078  -24.757 52.715 1.00 32.62  ? 285 ASP F O   1 
ATOM   15306 C CB  . ASP F 1 83  ? 15.867  -25.626 52.589 1.00 32.43  ? 285 ASP F CB  1 
ATOM   15307 C CG  . ASP F 1 83  ? 16.600  -24.352 52.255 1.00 38.79  ? 285 ASP F CG  1 
ATOM   15308 O OD1 . ASP F 1 83  ? 16.554  -23.423 53.081 1.00 43.25  ? 285 ASP F OD1 1 
ATOM   15309 O OD2 . ASP F 1 83  ? 17.222  -24.279 51.174 1.00 42.18  ? 285 ASP F OD2 1 
ATOM   15310 N N   . PHE F 1 84  ? 13.674  -23.616 54.564 1.00 31.06  ? 286 PHE F N   1 
ATOM   15311 C CA  . PHE F 1 84  ? 12.664  -22.571 54.425 1.00 28.45  ? 286 PHE F CA  1 
ATOM   15312 C C   . PHE F 1 84  ? 13.238  -21.240 53.936 1.00 26.51  ? 286 PHE F C   1 
ATOM   15313 O O   . PHE F 1 84  ? 12.540  -20.222 53.963 1.00 26.04  ? 286 PHE F O   1 
ATOM   15314 C CB  . PHE F 1 84  ? 11.857  -22.414 55.718 1.00 26.11  ? 286 PHE F CB  1 
ATOM   15315 C CG  . PHE F 1 84  ? 12.679  -22.298 56.965 1.00 26.61  ? 286 PHE F CG  1 
ATOM   15316 C CD1 . PHE F 1 84  ? 13.047  -21.063 57.461 1.00 27.14  ? 286 PHE F CD1 1 
ATOM   15317 C CD2 . PHE F 1 84  ? 13.048  -23.432 57.668 1.00 26.86  ? 286 PHE F CD2 1 
ATOM   15318 C CE1 . PHE F 1 84  ? 13.780  -20.965 58.627 1.00 26.93  ? 286 PHE F CE1 1 
ATOM   15319 C CE2 . PHE F 1 84  ? 13.787  -23.338 58.827 1.00 27.64  ? 286 PHE F CE2 1 
ATOM   15320 C CZ  . PHE F 1 84  ? 14.154  -22.104 59.306 1.00 27.01  ? 286 PHE F CZ  1 
ATOM   15321 N N   . ASN F 1 85  ? 14.496  -21.227 53.499 1.00 24.30  ? 287 ASN F N   1 
ATOM   15322 C CA  . ASN F 1 85  ? 15.288  -20.029 53.231 1.00 23.15  ? 287 ASN F CA  1 
ATOM   15323 C C   . ASN F 1 85  ? 14.728  -19.124 52.113 1.00 22.87  ? 287 ASN F C   1 
ATOM   15324 O O   . ASN F 1 85  ? 15.306  -18.061 51.879 1.00 23.67  ? 287 ASN F O   1 
ATOM   15325 C CB  . ASN F 1 85  ? 16.728  -20.433 52.899 1.00 23.46  ? 287 ASN F CB  1 
ATOM   15326 C CG  . ASN F 1 85  ? 17.685  -19.266 52.908 1.00 24.25  ? 287 ASN F CG  1 
ATOM   15327 O OD1 . ASN F 1 85  ? 17.470  -18.281 53.603 1.00 22.83  ? 287 ASN F OD1 1 
ATOM   15328 N ND2 . ASN F 1 85  ? 18.762  -19.381 52.148 1.00 26.70  ? 287 ASN F ND2 1 
ATOM   15329 N N   . ARG F 1 86  ? 13.673  -19.480 51.390 1.00 20.75  ? 288 ARG F N   1 
ATOM   15330 C CA  . ARG F 1 86  ? 13.109  -18.584 50.387 1.00 20.82  ? 288 ARG F CA  1 
ATOM   15331 C C   . ARG F 1 86  ? 11.924  -17.819 50.967 1.00 21.07  ? 288 ARG F C   1 
ATOM   15332 O O   . ARG F 1 86  ? 11.188  -18.336 51.809 1.00 21.17  ? 288 ARG F O   1 
ATOM   15333 C CB  . ARG F 1 86  ? 12.682  -19.347 49.131 1.00 17.44  ? 288 ARG F CB  1 
ATOM   15334 C CG  . ARG F 1 86  ? 13.824  -20.051 48.435 1.00 17.95  ? 288 ARG F CG  1 
ATOM   15335 C CD  . ARG F 1 86  ? 13.369  -20.778 47.189 1.00 18.83  ? 288 ARG F CD  1 
ATOM   15336 N NE  . ARG F 1 86  ? 12.948  -19.869 46.132 1.00 20.15  ? 288 ARG F NE  1 
ATOM   15337 C CZ  . ARG F 1 86  ? 12.464  -20.263 44.960 1.00 21.02  ? 288 ARG F CZ  1 
ATOM   15338 N NH1 . ARG F 1 86  ? 12.335  -21.551 44.693 1.00 20.60  ? 288 ARG F NH1 1 
ATOM   15339 N NH2 . ARG F 1 86  ? 12.109  -19.369 44.053 1.00 19.10  ? 288 ARG F NH2 1 
ATOM   15340 N N   . PHE F 1 87  ? 11.758  -16.564 50.525 1.00 17.24  ? 289 PHE F N   1 
ATOM   15341 C CA  . PHE F 1 87  ? 10.712  -15.713 51.095 1.00 17.96  ? 289 PHE F CA  1 
ATOM   15342 C C   . PHE F 1 87  ? 9.308   -16.265 50.878 1.00 19.27  ? 289 PHE F C   1 
ATOM   15343 O O   . PHE F 1 87  ? 8.505   -16.262 51.816 1.00 18.86  ? 289 PHE F O   1 
ATOM   15344 C CB  . PHE F 1 87  ? 10.781  -14.288 50.541 1.00 16.04  ? 289 PHE F CB  1 
ATOM   15345 C CG  . PHE F 1 87  ? 11.870  -13.444 51.141 1.00 16.35  ? 289 PHE F CG  1 
ATOM   15346 C CD1 . PHE F 1 87  ? 11.714  -12.896 52.400 1.00 15.41  ? 289 PHE F CD1 1 
ATOM   15347 C CD2 . PHE F 1 87  ? 13.014  -13.146 50.432 1.00 15.95  ? 289 PHE F CD2 1 
ATOM   15348 C CE1 . PHE F 1 87  ? 12.695  -12.106 52.952 1.00 15.82  ? 289 PHE F CE1 1 
ATOM   15349 C CE2 . PHE F 1 87  ? 13.993  -12.351 50.980 1.00 15.44  ? 289 PHE F CE2 1 
ATOM   15350 C CZ  . PHE F 1 87  ? 13.833  -11.834 52.242 1.00 15.14  ? 289 PHE F CZ  1 
ATOM   15351 N N   . HIS F 1 88  ? 8.976   -16.726 49.668 1.00 16.36  ? 290 HIS F N   1 
ATOM   15352 C CA  . HIS F 1 88  ? 7.596   -17.138 49.422 1.00 18.09  ? 290 HIS F CA  1 
ATOM   15353 C C   . HIS F 1 88  ? 7.158   -18.306 50.290 1.00 19.18  ? 290 HIS F C   1 
ATOM   15354 O O   . HIS F 1 88  ? 5.964   -18.618 50.312 1.00 20.65  ? 290 HIS F O   1 
ATOM   15355 C CB  . HIS F 1 88  ? 7.359   -17.492 47.953 1.00 15.21  ? 290 HIS F CB  1 
ATOM   15356 C CG  . HIS F 1 88  ? 8.263   -18.558 47.422 1.00 16.42  ? 290 HIS F CG  1 
ATOM   15357 N ND1 . HIS F 1 88  ? 8.238   -19.855 47.881 1.00 18.37  ? 290 HIS F ND1 1 
ATOM   15358 C CD2 . HIS F 1 88  ? 9.158   -18.537 46.409 1.00 16.08  ? 290 HIS F CD2 1 
ATOM   15359 C CE1 . HIS F 1 88  ? 9.118   -20.574 47.211 1.00 17.63  ? 290 HIS F CE1 1 
ATOM   15360 N NE2 . HIS F 1 88  ? 9.685   -19.799 46.306 1.00 16.86  ? 290 HIS F NE2 1 
ATOM   15361 N N   . CYS F 1 89  ? 8.082   -18.963 50.986 1.00 20.12  ? 291 CYS F N   1 
ATOM   15362 C CA  . CYS F 1 89  ? 7.680   -19.938 51.989 1.00 22.01  ? 291 CYS F CA  1 
ATOM   15363 C C   . CYS F 1 89  ? 6.864   -19.276 53.089 1.00 20.96  ? 291 CYS F C   1 
ATOM   15364 O O   . CYS F 1 89  ? 5.846   -19.817 53.529 1.00 20.33  ? 291 CYS F O   1 
ATOM   15365 C CB  . CYS F 1 89  ? 8.912   -20.610 52.592 1.00 26.82  ? 291 CYS F CB  1 
ATOM   15366 S SG  . CYS F 1 89  ? 9.960   -21.493 51.423 1.00 35.65  ? 291 CYS F SG  1 
ATOM   15367 N N   . HIS F 1 90  ? 7.321   -18.120 53.567 1.00 22.50  ? 292 HIS F N   1 
ATOM   15368 C CA  . HIS F 1 90  ? 6.751   -17.481 54.742 1.00 21.43  ? 292 HIS F CA  1 
ATOM   15369 C C   . HIS F 1 90  ? 5.721   -16.399 54.441 1.00 21.16  ? 292 HIS F C   1 
ATOM   15370 O O   . HIS F 1 90  ? 5.016   -15.972 55.360 1.00 22.52  ? 292 HIS F O   1 
ATOM   15371 C CB  . HIS F 1 90  ? 7.888   -16.888 55.574 1.00 22.37  ? 292 HIS F CB  1 
ATOM   15372 C CG  . HIS F 1 90  ? 8.975   -17.873 55.861 1.00 23.42  ? 292 HIS F CG  1 
ATOM   15373 N ND1 . HIS F 1 90  ? 8.814   -18.924 56.735 1.00 24.89  ? 292 HIS F ND1 1 
ATOM   15374 C CD2 . HIS F 1 90  ? 10.217  -18.002 55.342 1.00 23.72  ? 292 HIS F CD2 1 
ATOM   15375 C CE1 . HIS F 1 90  ? 9.922   -19.642 56.765 1.00 25.44  ? 292 HIS F CE1 1 
ATOM   15376 N NE2 . HIS F 1 90  ? 10.790  -19.102 55.930 1.00 24.60  ? 292 HIS F NE2 1 
ATOM   15377 N N   . PHE F 1 91  ? 5.602   -15.953 53.194 1.00 18.46  ? 293 PHE F N   1 
ATOM   15378 C CA  . PHE F 1 91  ? 4.721   -14.847 52.840 1.00 17.49  ? 293 PHE F CA  1 
ATOM   15379 C C   . PHE F 1 91  ? 3.813   -15.269 51.701 1.00 17.93  ? 293 PHE F C   1 
ATOM   15380 O O   . PHE F 1 91  ? 4.271   -15.879 50.731 1.00 19.54  ? 293 PHE F O   1 
ATOM   15381 C CB  . PHE F 1 91  ? 5.506   -13.598 52.413 1.00 15.16  ? 293 PHE F CB  1 
ATOM   15382 C CG  . PHE F 1 91  ? 6.268   -12.937 53.521 1.00 14.89  ? 293 PHE F CG  1 
ATOM   15383 C CD1 . PHE F 1 91  ? 5.661   -11.999 54.333 1.00 14.99  ? 293 PHE F CD1 1 
ATOM   15384 C CD2 . PHE F 1 91  ? 7.595   -13.242 53.739 1.00 15.37  ? 293 PHE F CD2 1 
ATOM   15385 C CE1 . PHE F 1 91  ? 6.365   -11.386 55.347 1.00 15.23  ? 293 PHE F CE1 1 
ATOM   15386 C CE2 . PHE F 1 91  ? 8.299   -12.637 54.750 1.00 15.92  ? 293 PHE F CE2 1 
ATOM   15387 C CZ  . PHE F 1 91  ? 7.685   -11.708 55.555 1.00 15.63  ? 293 PHE F CZ  1 
ATOM   15388 N N   . SER F 1 92  ? 2.533   -14.942 51.816 1.00 13.74  ? 294 SER F N   1 
ATOM   15389 C CA  . SER F 1 92  ? 1.656   -15.036 50.672 1.00 13.11  ? 294 SER F CA  1 
ATOM   15390 C C   . SER F 1 92  ? 1.887   -13.827 49.773 1.00 12.37  ? 294 SER F C   1 
ATOM   15391 O O   . SER F 1 92  ? 2.470   -12.831 50.203 1.00 11.19  ? 294 SER F O   1 
ATOM   15392 C CB  . SER F 1 92  ? 0.201   -15.109 51.118 1.00 12.24  ? 294 SER F CB  1 
ATOM   15393 O OG  . SER F 1 92  ? -0.183  -13.937 51.807 1.00 13.46  ? 294 SER F OG  1 
ATOM   15394 N N   . PRO F 1 93  ? 1.475   -13.903 48.507 1.00 8.89   ? 295 PRO F N   1 
ATOM   15395 C CA  . PRO F 1 93  ? 1.581   -12.714 47.651 1.00 8.97   ? 295 PRO F CA  1 
ATOM   15396 C C   . PRO F 1 93  ? 0.848   -11.510 48.212 1.00 9.75   ? 295 PRO F C   1 
ATOM   15397 O O   . PRO F 1 93  ? 1.269   -10.371 47.984 1.00 9.06   ? 295 PRO F O   1 
ATOM   15398 C CB  . PRO F 1 93  ? 0.971   -13.189 46.329 1.00 9.34   ? 295 PRO F CB  1 
ATOM   15399 C CG  . PRO F 1 93  ? 1.195   -14.644 46.328 1.00 10.57  ? 295 PRO F CG  1 
ATOM   15400 C CD  . PRO F 1 93  ? 1.048   -15.086 47.747 1.00 10.11  ? 295 PRO F CD  1 
ATOM   15401 N N   . ARG F 1 94  ? -0.244  -11.728 48.947 1.00 10.01  ? 296 ARG F N   1 
ATOM   15402 C CA  . ARG F 1 94  ? -0.938  -10.609 49.573 1.00 11.92  ? 296 ARG F CA  1 
ATOM   15403 C C   . ARG F 1 94  ? -0.128  -10.036 50.725 1.00 11.59  ? 296 ARG F C   1 
ATOM   15404 O O   . ARG F 1 94  ? 0.016   -8.816  50.845 1.00 10.98  ? 296 ARG F O   1 
ATOM   15405 C CB  . ARG F 1 94  ? -2.314  -11.043 50.065 1.00 8.64   ? 296 ARG F CB  1 
ATOM   15406 C CG  . ARG F 1 94  ? -3.056  -9.942  50.796 1.00 12.04  ? 296 ARG F CG  1 
ATOM   15407 C CD  . ARG F 1 94  ? -3.453  -8.829  49.850 1.00 16.21  ? 296 ARG F CD  1 
ATOM   15408 N NE  . ARG F 1 94  ? -4.068  -7.702  50.544 1.00 22.20  ? 296 ARG F NE  1 
ATOM   15409 C CZ  . ARG F 1 94  ? -3.412  -6.620  50.950 1.00 24.31  ? 296 ARG F CZ  1 
ATOM   15410 N NH1 . ARG F 1 94  ? -2.118  -6.497  50.706 1.00 23.88  ? 296 ARG F NH1 1 
ATOM   15411 N NH2 . ARG F 1 94  ? -4.055  -5.646  51.576 1.00 24.10  ? 296 ARG F NH2 1 
ATOM   15412 N N   . ASP F 1 95  ? 0.401   -10.900 51.593 1.00 12.36  ? 297 ASP F N   1 
ATOM   15413 C CA  . ASP F 1 95  ? 1.209   -10.421 52.708 1.00 13.17  ? 297 ASP F CA  1 
ATOM   15414 C C   . ASP F 1 95  ? 2.484   -9.756  52.216 1.00 11.35  ? 297 ASP F C   1 
ATOM   15415 O O   . ASP F 1 95  ? 2.998   -8.834  52.856 1.00 10.96  ? 297 ASP F O   1 
ATOM   15416 C CB  . ASP F 1 95  ? 1.542   -11.574 53.649 1.00 13.80  ? 297 ASP F CB  1 
ATOM   15417 C CG  . ASP F 1 95  ? 0.339   -12.061 54.411 1.00 19.40  ? 297 ASP F CG  1 
ATOM   15418 O OD1 . ASP F 1 95  ? -0.661  -11.319 54.481 1.00 21.04  ? 297 ASP F OD1 1 
ATOM   15419 O OD2 . ASP F 1 95  ? 0.389   -13.192 54.932 1.00 22.53  ? 297 ASP F OD2 1 
ATOM   15420 N N   . TRP F 1 96  ? 3.011   -10.213 51.082 1.00 11.13  ? 298 TRP F N   1 
ATOM   15421 C CA  . TRP F 1 96  ? 4.199   -9.582  50.526 1.00 10.25  ? 298 TRP F CA  1 
ATOM   15422 C C   . TRP F 1 96  ? 3.871   -8.204  49.973 1.00 10.37  ? 298 TRP F C   1 
ATOM   15423 O O   . TRP F 1 96  ? 4.673   -7.274  50.095 1.00 10.06  ? 298 TRP F O   1 
ATOM   15424 C CB  . TRP F 1 96  ? 4.806   -10.472 49.447 1.00 10.83  ? 298 TRP F CB  1 
ATOM   15425 C CG  . TRP F 1 96  ? 6.059   -9.930  48.861 1.00 9.90   ? 298 TRP F CG  1 
ATOM   15426 C CD1 . TRP F 1 96  ? 6.201   -9.335  47.649 1.00 9.49   ? 298 TRP F CD1 1 
ATOM   15427 C CD2 . TRP F 1 96  ? 7.357   -9.936  49.460 1.00 10.69  ? 298 TRP F CD2 1 
ATOM   15428 N NE1 . TRP F 1 96  ? 7.505   -8.969  47.452 1.00 10.39  ? 298 TRP F NE1 1 
ATOM   15429 C CE2 . TRP F 1 96  ? 8.236   -9.324  48.553 1.00 10.61  ? 298 TRP F CE2 1 
ATOM   15430 C CE3 . TRP F 1 96  ? 7.859   -10.395 50.679 1.00 10.76  ? 298 TRP F CE3 1 
ATOM   15431 C CZ2 . TRP F 1 96  ? 9.588   -9.161  48.822 1.00 10.31  ? 298 TRP F CZ2 1 
ATOM   15432 C CZ3 . TRP F 1 96  ? 9.201   -10.233 50.943 1.00 10.77  ? 298 TRP F CZ3 1 
ATOM   15433 C CH2 . TRP F 1 96  ? 10.051  -9.621  50.020 1.00 10.57  ? 298 TRP F CH2 1 
ATOM   15434 N N   . GLN F 1 97  ? 2.694   -8.050  49.364 1.00 7.77   ? 299 GLN F N   1 
ATOM   15435 C CA  . GLN F 1 97  ? 2.261   -6.730  48.919 1.00 8.34   ? 299 GLN F CA  1 
ATOM   15436 C C   . GLN F 1 97  ? 2.063   -5.797  50.102 1.00 9.84   ? 299 GLN F C   1 
ATOM   15437 O O   . GLN F 1 97  ? 2.476   -4.633  50.062 1.00 10.11  ? 299 GLN F O   1 
ATOM   15438 C CB  . GLN F 1 97  ? 0.957   -6.838  48.140 1.00 8.53   ? 299 GLN F CB  1 
ATOM   15439 C CG  . GLN F 1 97  ? 0.598   -5.592  47.373 1.00 8.39   ? 299 GLN F CG  1 
ATOM   15440 C CD  . GLN F 1 97  ? -0.753  -5.702  46.735 1.00 9.95   ? 299 GLN F CD  1 
ATOM   15441 O OE1 . GLN F 1 97  ? -1.509  -6.618  47.028 1.00 11.38  ? 299 GLN F OE1 1 
ATOM   15442 N NE2 . GLN F 1 97  ? -1.037  -4.818  45.801 1.00 9.90   ? 299 GLN F NE2 1 
ATOM   15443 N N   . ARG F 1 98  ? 1.417   -6.295  51.157 1.00 10.26  ? 300 ARG F N   1 
ATOM   15444 C CA  . ARG F 1 98  ? 1.173   -5.496  52.350 1.00 12.81  ? 300 ARG F CA  1 
ATOM   15445 C C   . ARG F 1 98  ? 2.484   -5.047  52.981 1.00 11.39  ? 300 ARG F C   1 
ATOM   15446 O O   . ARG F 1 98  ? 2.545   -4.004  53.638 1.00 11.38  ? 300 ARG F O   1 
ATOM   15447 C CB  . ARG F 1 98  ? 0.344   -6.315  53.341 1.00 6.59   ? 300 ARG F CB  1 
ATOM   15448 C CG  . ARG F 1 98  ? -0.135  -5.565  54.555 1.00 15.05  ? 300 ARG F CG  1 
ATOM   15449 C CD  . ARG F 1 98  ? -1.011  -6.437  55.446 1.00 23.57  ? 300 ARG F CD  1 
ATOM   15450 N NE  . ARG F 1 98  ? -2.245  -6.890  54.809 1.00 33.50  ? 300 ARG F NE  1 
ATOM   15451 C CZ  . ARG F 1 98  ? -2.481  -8.146  54.443 1.00 37.71  ? 300 ARG F CZ  1 
ATOM   15452 N NH1 . ARG F 1 98  ? -1.569  -9.079  54.652 1.00 38.20  ? 300 ARG F NH1 1 
ATOM   15453 N NH2 . ARG F 1 98  ? -3.634  -8.475  53.876 1.00 38.05  ? 300 ARG F NH2 1 
ATOM   15454 N N   . LEU F 1 99  ? 3.546   -5.828  52.783 1.00 12.30  ? 301 LEU F N   1 
ATOM   15455 C CA  . LEU F 1 99  ? 4.849   -5.511  53.357 1.00 10.85  ? 301 LEU F CA  1 
ATOM   15456 C C   . LEU F 1 99  ? 5.561   -4.423  52.562 1.00 11.47  ? 301 LEU F C   1 
ATOM   15457 O O   . LEU F 1 99  ? 6.099   -3.472  53.136 1.00 11.62  ? 301 LEU F O   1 
ATOM   15458 C CB  . LEU F 1 99  ? 5.703   -6.777  53.406 1.00 11.22  ? 301 LEU F CB  1 
ATOM   15459 C CG  . LEU F 1 99  ? 7.165   -6.676  53.838 1.00 11.05  ? 301 LEU F CG  1 
ATOM   15460 C CD1 . LEU F 1 99  ? 7.265   -6.249  55.275 1.00 10.39  ? 301 LEU F CD1 1 
ATOM   15461 C CD2 . LEU F 1 99  ? 7.874   -7.997  53.619 1.00 11.19  ? 301 LEU F CD2 1 
ATOM   15462 N N   . ILE F 1 100 ? 5.581   -4.552  51.236 1.00 10.65  ? 302 ILE F N   1 
ATOM   15463 C CA  . ILE F 1 100 ? 6.471   -3.729  50.424 1.00 10.23  ? 302 ILE F CA  1 
ATOM   15464 C C   . ILE F 1 100 ? 5.891   -2.337  50.201 1.00 9.89   ? 302 ILE F C   1 
ATOM   15465 O O   . ILE F 1 100 ? 6.637   -1.363  50.048 1.00 11.14  ? 302 ILE F O   1 
ATOM   15466 C CB  . ILE F 1 100 ? 6.779   -4.435  49.094 1.00 8.83   ? 302 ILE F CB  1 
ATOM   15467 C CG1 . ILE F 1 100 ? 5.498   -4.659  48.299 1.00 11.09  ? 302 ILE F CG1 1 
ATOM   15468 C CG2 . ILE F 1 100 ? 7.469   -5.744  49.353 1.00 11.46  ? 302 ILE F CG2 1 
ATOM   15469 C CD1 . ILE F 1 100 ? 5.729   -5.215  46.937 1.00 15.00  ? 302 ILE F CD1 1 
ATOM   15470 N N   . ASN F 1 101 ? 4.564   -2.215  50.158 1.00 8.95   ? 303 ASN F N   1 
ATOM   15471 C CA  . ASN F 1 101 ? 3.970   -0.912  49.884 1.00 8.74   ? 303 ASN F CA  1 
ATOM   15472 C C   . ASN F 1 101 ? 3.934   -0.038  51.128 1.00 9.24   ? 303 ASN F C   1 
ATOM   15473 O O   . ASN F 1 101 ? 3.886   1.192   51.025 1.00 9.58   ? 303 ASN F O   1 
ATOM   15474 C CB  . ASN F 1 101 ? 2.563   -1.075  49.320 1.00 9.05   ? 303 ASN F CB  1 
ATOM   15475 C CG  . ASN F 1 101 ? 2.561   -1.588  47.906 1.00 9.19   ? 303 ASN F CG  1 
ATOM   15476 O OD1 . ASN F 1 101 ? 3.551   -1.475  47.194 1.00 8.32   ? 303 ASN F OD1 1 
ATOM   15477 N ND2 . ASN F 1 101 ? 1.434   -2.129  47.478 1.00 7.73   ? 303 ASN F ND2 1 
ATOM   15478 N N   . ASN F 1 102 ? 3.902   -0.648  52.308 1.00 10.76  ? 304 ASN F N   1 
ATOM   15479 C CA  . ASN F 1 102 ? 3.694   0.086   53.547 1.00 11.23  ? 304 ASN F CA  1 
ATOM   15480 C C   . ASN F 1 102 ? 4.966   0.341   54.345 1.00 11.59  ? 304 ASN F C   1 
ATOM   15481 O O   . ASN F 1 102 ? 4.899   1.002   55.383 1.00 12.01  ? 304 ASN F O   1 
ATOM   15482 C CB  . ASN F 1 102 ? 2.682   -0.660  54.407 1.00 9.43   ? 304 ASN F CB  1 
ATOM   15483 C CG  . ASN F 1 102 ? 1.334   -0.735  53.751 1.00 12.42  ? 304 ASN F CG  1 
ATOM   15484 O OD1 . ASN F 1 102 ? 1.013   0.075   52.885 1.00 15.85  ? 304 ASN F OD1 1 
ATOM   15485 N ND2 . ASN F 1 102 ? 0.535   -1.715  54.145 1.00 12.77  ? 304 ASN F ND2 1 
ATOM   15486 N N   . ASN F 1 103 ? 6.118   -0.154  53.905 1.00 13.95  ? 305 ASN F N   1 
ATOM   15487 C CA  . ASN F 1 103 ? 7.291   -0.191  54.767 1.00 13.80  ? 305 ASN F CA  1 
ATOM   15488 C C   . ASN F 1 103 ? 8.558   0.186   54.013 1.00 13.84  ? 305 ASN F C   1 
ATOM   15489 O O   . ASN F 1 103 ? 8.684   -0.059  52.812 1.00 14.05  ? 305 ASN F O   1 
ATOM   15490 C CB  . ASN F 1 103 ? 7.469   -1.580  55.393 1.00 12.32  ? 305 ASN F CB  1 
ATOM   15491 C CG  . ASN F 1 103 ? 6.389   -1.909  56.399 1.00 13.10  ? 305 ASN F CG  1 
ATOM   15492 O OD1 . ASN F 1 103 ? 6.410   -1.425  57.526 1.00 15.85  ? 305 ASN F OD1 1 
ATOM   15493 N ND2 . ASN F 1 103 ? 5.440   -2.740  55.997 1.00 13.50  ? 305 ASN F ND2 1 
ATOM   15494 N N   . TRP F 1 104 ? 9.495   0.790   54.746 1.00 14.73  ? 306 TRP F N   1 
ATOM   15495 C CA  . TRP F 1 104 ? 10.846  1.076   54.275 1.00 15.22  ? 306 TRP F CA  1 
ATOM   15496 C C   . TRP F 1 104 ? 11.864  0.000   54.606 1.00 15.12  ? 306 TRP F C   1 
ATOM   15497 O O   . TRP F 1 104 ? 13.002  0.089   54.140 1.00 16.23  ? 306 TRP F O   1 
ATOM   15498 C CB  . TRP F 1 104 ? 11.346  2.397   54.861 1.00 12.65  ? 306 TRP F CB  1 
ATOM   15499 C CG  . TRP F 1 104 ? 10.871  3.589   54.147 1.00 15.67  ? 306 TRP F CG  1 
ATOM   15500 C CD1 . TRP F 1 104 ? 10.282  3.627   52.923 1.00 16.87  ? 306 TRP F CD1 1 
ATOM   15501 C CD2 . TRP F 1 104 ? 10.909  4.933   54.620 1.00 18.00  ? 306 TRP F CD2 1 
ATOM   15502 N NE1 . TRP F 1 104 ? 9.975   4.918   52.590 1.00 17.82  ? 306 TRP F NE1 1 
ATOM   15503 C CE2 . TRP F 1 104 ? 10.340  5.738   53.622 1.00 18.55  ? 306 TRP F CE2 1 
ATOM   15504 C CE3 . TRP F 1 104 ? 11.370  5.536   55.793 1.00 17.37  ? 306 TRP F CE3 1 
ATOM   15505 C CZ2 . TRP F 1 104 ? 10.223  7.115   53.755 1.00 19.03  ? 306 TRP F CZ2 1 
ATOM   15506 C CZ3 . TRP F 1 104 ? 11.249  6.899   55.926 1.00 17.62  ? 306 TRP F CZ3 1 
ATOM   15507 C CH2 . TRP F 1 104 ? 10.686  7.676   54.912 1.00 19.20  ? 306 TRP F CH2 1 
ATOM   15508 N N   . GLY F 1 105 ? 11.508  -0.997  55.406 1.00 16.70  ? 307 GLY F N   1 
ATOM   15509 C CA  . GLY F 1 105 ? 12.484  -2.018  55.731 1.00 16.58  ? 307 GLY F CA  1 
ATOM   15510 C C   . GLY F 1 105 ? 11.925  -3.070  56.657 1.00 16.25  ? 307 GLY F C   1 
ATOM   15511 O O   . GLY F 1 105 ? 10.931  -2.861  57.352 1.00 15.45  ? 307 GLY F O   1 
ATOM   15512 N N   . PHE F 1 106 ? 12.600  -4.214  56.664 1.00 16.96  ? 308 PHE F N   1 
ATOM   15513 C CA  . PHE F 1 106 ? 12.192  -5.339  57.491 1.00 17.91  ? 308 PHE F CA  1 
ATOM   15514 C C   . PHE F 1 106 ? 13.410  -6.209  57.755 1.00 18.18  ? 308 PHE F C   1 
ATOM   15515 O O   . PHE F 1 106 ? 14.450  -6.065  57.111 1.00 18.28  ? 308 PHE F O   1 
ATOM   15516 C CB  . PHE F 1 106 ? 11.062  -6.140  56.839 1.00 15.30  ? 308 PHE F CB  1 
ATOM   15517 C CG  . PHE F 1 106 ? 11.421  -6.727  55.511 1.00 16.50  ? 308 PHE F CG  1 
ATOM   15518 C CD1 . PHE F 1 106 ? 11.950  -8.001  55.423 1.00 16.93  ? 308 PHE F CD1 1 
ATOM   15519 C CD2 . PHE F 1 106 ? 11.242  -6.001  54.351 1.00 18.27  ? 308 PHE F CD2 1 
ATOM   15520 C CE1 . PHE F 1 106 ? 12.280  -8.538  54.208 1.00 18.26  ? 308 PHE F CE1 1 
ATOM   15521 C CE2 . PHE F 1 106 ? 11.574  -6.537  53.133 1.00 18.98  ? 308 PHE F CE2 1 
ATOM   15522 C CZ  . PHE F 1 106 ? 12.095  -7.807  53.061 1.00 17.99  ? 308 PHE F CZ  1 
ATOM   15523 N N   . ARG F 1 107 ? 13.260  -7.124  58.707 1.00 22.18  ? 309 ARG F N   1 
ATOM   15524 C CA  . ARG F 1 107 ? 14.326  -8.031  59.109 1.00 22.47  ? 309 ARG F CA  1 
ATOM   15525 C C   . ARG F 1 107 ? 13.787  -9.045  60.108 1.00 21.87  ? 309 ARG F C   1 
ATOM   15526 O O   . ARG F 1 107 ? 12.878  -8.733  60.887 1.00 22.43  ? 309 ARG F O   1 
ATOM   15527 C CB  . ARG F 1 107 ? 15.498  -7.269  59.728 1.00 18.30  ? 309 ARG F CB  1 
ATOM   15528 C CG  . ARG F 1 107 ? 15.138  -6.484  60.962 1.00 19.78  ? 309 ARG F CG  1 
ATOM   15529 C CD  . ARG F 1 107 ? 16.357  -5.838  61.565 1.00 23.11  ? 309 ARG F CD  1 
ATOM   15530 N NE  . ARG F 1 107 ? 16.031  -5.121  62.790 1.00 27.84  ? 309 ARG F NE  1 
ATOM   15531 C CZ  . ARG F 1 107 ? 16.908  -4.424  63.498 1.00 30.39  ? 309 ARG F CZ  1 
ATOM   15532 N NH1 . ARG F 1 107 ? 18.169  -4.350  63.099 1.00 31.69  ? 309 ARG F NH1 1 
ATOM   15533 N NH2 . ARG F 1 107 ? 16.527  -3.801  64.602 1.00 31.49  ? 309 ARG F NH2 1 
ATOM   15534 N N   . PRO F 1 108 ? 14.302  -10.277 60.064 1.00 23.78  ? 310 PRO F N   1 
ATOM   15535 C CA  . PRO F 1 108 ? 13.830  -11.330 60.966 1.00 23.77  ? 310 PRO F CA  1 
ATOM   15536 C C   . PRO F 1 108 ? 14.314  -11.157 62.402 1.00 25.19  ? 310 PRO F C   1 
ATOM   15537 O O   . PRO F 1 108 ? 15.410  -10.654 62.623 1.00 24.49  ? 310 PRO F O   1 
ATOM   15538 C CB  . PRO F 1 108 ? 14.415  -12.596 60.348 1.00 23.62  ? 310 PRO F CB  1 
ATOM   15539 C CG  . PRO F 1 108 ? 15.616  -12.138 59.604 1.00 22.16  ? 310 PRO F CG  1 
ATOM   15540 C CD  . PRO F 1 108 ? 15.306  -10.766 59.106 1.00 22.36  ? 310 PRO F CD  1 
ATOM   15541 N N   . LYS F 1 109 ? 13.481  -11.532 63.368 1.00 28.89  ? 311 LYS F N   1 
ATOM   15542 C CA  . LYS F 1 109 ? 13.849  -11.431 64.773 1.00 31.21  ? 311 LYS F CA  1 
ATOM   15543 C C   . LYS F 1 109 ? 13.943  -12.776 65.497 1.00 31.09  ? 311 LYS F C   1 
ATOM   15544 O O   . LYS F 1 109 ? 14.960  -13.086 66.099 1.00 30.96  ? 311 LYS F O   1 
ATOM   15545 C CB  . LYS F 1 109 ? 12.857  -10.532 65.507 1.00 23.48  ? 311 LYS F CB  1 
ATOM   15546 C CG  . LYS F 1 109 ? 12.668  -9.168  64.874 1.00 30.31  ? 311 LYS F CG  1 
ATOM   15547 C CD  . LYS F 1 109 ? 13.871  -8.274  65.113 1.00 37.44  ? 311 LYS F CD  1 
ATOM   15548 C CE  . LYS F 1 109 ? 14.050  -7.976  66.589 1.00 42.93  ? 311 LYS F CE  1 
ATOM   15549 N NZ  . LYS F 1 109 ? 15.041  -6.889  66.797 1.00 40.89  ? 311 LYS F NZ  1 
ATOM   15550 N N   . ARG F 1 110 ? 12.887  -13.579 65.417 1.00 32.26  ? 312 ARG F N   1 
ATOM   15551 C CA  . ARG F 1 110 ? 12.839  -14.874 66.098 1.00 33.42  ? 312 ARG F CA  1 
ATOM   15552 C C   . ARG F 1 110 ? 12.324  -15.995 65.215 1.00 32.25  ? 312 ARG F C   1 
ATOM   15553 O O   . ARG F 1 110 ? 11.541  -15.769 64.304 1.00 31.99  ? 312 ARG F O   1 
ATOM   15554 C CB  . ARG F 1 110 ? 11.962  -14.783 67.343 1.00 30.41  ? 312 ARG F CB  1 
ATOM   15555 C CG  . ARG F 1 110 ? 12.733  -14.610 68.635 1.00 39.81  ? 312 ARG F CG  1 
ATOM   15556 C CD  . ARG F 1 110 ? 12.018  -13.649 69.563 1.00 48.73  ? 312 ARG F CD  1 
ATOM   15557 N NE  . ARG F 1 110 ? 12.176  -12.272 69.111 1.00 58.51  ? 312 ARG F NE  1 
ATOM   15558 C CZ  . ARG F 1 110 ? 11.555  -11.230 69.649 1.00 63.47  ? 312 ARG F CZ  1 
ATOM   15559 N NH1 . ARG F 1 110 ? 11.765  -10.013 69.166 1.00 65.45  ? 312 ARG F NH1 1 
ATOM   15560 N NH2 . ARG F 1 110 ? 10.725  -11.405 70.667 1.00 64.63  ? 312 ARG F NH2 1 
ATOM   15561 N N   . LEU F 1 111 ? 12.764  -17.213 65.503 1.00 33.60  ? 313 LEU F N   1 
ATOM   15562 C CA  . LEU F 1 111 ? 12.362  -18.378 64.728 1.00 32.33  ? 313 LEU F CA  1 
ATOM   15563 C C   . LEU F 1 111 ? 11.844  -19.517 65.609 1.00 32.62  ? 313 LEU F C   1 
ATOM   15564 O O   . LEU F 1 111 ? 12.394  -19.785 66.667 1.00 32.03  ? 313 LEU F O   1 
ATOM   15565 C CB  . LEU F 1 111 ? 13.556  -18.839 63.889 1.00 27.80  ? 313 LEU F CB  1 
ATOM   15566 C CG  . LEU F 1 111 ? 13.546  -20.092 63.021 1.00 27.73  ? 313 LEU F CG  1 
ATOM   15567 C CD1 . LEU F 1 111 ? 13.477  -21.356 63.859 1.00 29.01  ? 313 LEU F CD1 1 
ATOM   15568 C CD2 . LEU F 1 111 ? 12.429  -20.037 61.999 1.00 32.93  ? 313 LEU F CD2 1 
ATOM   15569 N N   . ASN F 1 112 ? 10.763  -20.162 65.182 1.00 33.50  ? 314 ASN F N   1 
ATOM   15570 C CA  . ASN F 1 112 ? 10.200  -21.303 65.898 1.00 34.05  ? 314 ASN F CA  1 
ATOM   15571 C C   . ASN F 1 112 ? 9.975   -22.425 64.888 1.00 32.66  ? 314 ASN F C   1 
ATOM   15572 O O   . ASN F 1 112 ? 9.510   -22.182 63.780 1.00 34.34  ? 314 ASN F O   1 
ATOM   15573 C CB  . ASN F 1 112 ? 8.910   -20.939 66.616 1.00 32.23  ? 314 ASN F CB  1 
ATOM   15574 C CG  . ASN F 1 112 ? 8.483   -22.003 67.601 1.00 38.40  ? 314 ASN F CG  1 
ATOM   15575 O OD1 . ASN F 1 112 ? 9.073   -23.079 67.659 1.00 41.41  ? 314 ASN F OD1 1 
ATOM   15576 N ND2 . ASN F 1 112 ? 7.456   -21.710 68.384 1.00 42.47  ? 314 ASN F ND2 1 
ATOM   15577 N N   . PHE F 1 113 ? 10.276  -23.657 65.278 1.00 35.79  ? 315 PHE F N   1 
ATOM   15578 C CA  . PHE F 1 113 ? 10.189  -24.784 64.361 1.00 34.36  ? 315 PHE F CA  1 
ATOM   15579 C C   . PHE F 1 113 ? 9.534   -25.950 65.083 1.00 34.70  ? 315 PHE F C   1 
ATOM   15580 O O   . PHE F 1 113 ? 9.860   -26.221 66.241 1.00 34.71  ? 315 PHE F O   1 
ATOM   15581 C CB  . PHE F 1 113 ? 11.586  -25.160 63.860 1.00 33.30  ? 315 PHE F CB  1 
ATOM   15582 C CG  . PHE F 1 113 ? 11.603  -26.266 62.852 1.00 32.70  ? 315 PHE F CG  1 
ATOM   15583 C CD1 . PHE F 1 113 ? 11.331  -26.005 61.522 1.00 33.25  ? 315 PHE F CD1 1 
ATOM   15584 C CD2 . PHE F 1 113 ? 11.918  -27.560 63.224 1.00 32.29  ? 315 PHE F CD2 1 
ATOM   15585 C CE1 . PHE F 1 113 ? 11.358  -27.013 60.588 1.00 33.25  ? 315 PHE F CE1 1 
ATOM   15586 C CE2 . PHE F 1 113 ? 11.948  -28.572 62.292 1.00 31.37  ? 315 PHE F CE2 1 
ATOM   15587 C CZ  . PHE F 1 113 ? 11.665  -28.299 60.972 1.00 32.84  ? 315 PHE F CZ  1 
ATOM   15588 N N   . LYS F 1 114 ? 8.603   -26.625 64.413 1.00 34.67  ? 316 LYS F N   1 
ATOM   15589 C CA  . LYS F 1 114 ? 7.908   -27.769 64.984 1.00 35.49  ? 316 LYS F CA  1 
ATOM   15590 C C   . LYS F 1 114 ? 7.784   -28.883 63.957 1.00 35.16  ? 316 LYS F C   1 
ATOM   15591 O O   . LYS F 1 114 ? 7.574   -28.639 62.766 1.00 36.58  ? 316 LYS F O   1 
ATOM   15592 C CB  . LYS F 1 114 ? 6.508   -27.408 65.493 1.00 34.25  ? 316 LYS F CB  1 
ATOM   15593 C CG  . LYS F 1 114 ? 6.484   -26.524 66.719 1.00 36.46  ? 316 LYS F CG  1 
ATOM   15594 C CD  . LYS F 1 114 ? 5.057   -26.187 67.111 1.00 39.25  ? 316 LYS F CD  1 
ATOM   15595 C CE  . LYS F 1 114 ? 5.014   -25.331 68.359 1.00 41.12  ? 316 LYS F CE  1 
ATOM   15596 N NZ  . LYS F 1 114 ? 3.621   -24.945 68.711 1.00 45.16  ? 316 LYS F NZ  1 
ATOM   15597 N N   . LEU F 1 115 ? 7.897   -30.116 64.445 1.00 38.88  ? 317 LEU F N   1 
ATOM   15598 C CA  . LEU F 1 115 ? 7.809   -31.313 63.618 1.00 38.24  ? 317 LEU F CA  1 
ATOM   15599 C C   . LEU F 1 115 ? 6.864   -32.282 64.309 1.00 38.52  ? 317 LEU F C   1 
ATOM   15600 O O   . LEU F 1 115 ? 7.124   -32.688 65.444 1.00 39.19  ? 317 LEU F O   1 
ATOM   15601 C CB  . LEU F 1 115 ? 9.194   -31.936 63.426 1.00 36.81  ? 317 LEU F CB  1 
ATOM   15602 C CG  . LEU F 1 115 ? 9.335   -33.224 62.622 1.00 39.91  ? 317 LEU F CG  1 
ATOM   15603 C CD1 . LEU F 1 115 ? 8.949   -32.993 61.183 1.00 40.72  ? 317 LEU F CD1 1 
ATOM   15604 C CD2 . LEU F 1 115 ? 10.754  -33.741 62.716 1.00 41.01  ? 317 LEU F CD2 1 
ATOM   15605 N N   . PHE F 1 116 ? 5.769   -32.643 63.645 1.00 37.38  ? 318 PHE F N   1 
ATOM   15606 C CA  . PHE F 1 116 ? 4.742   -33.437 64.305 1.00 37.93  ? 318 PHE F CA  1 
ATOM   15607 C C   . PHE F 1 116 ? 3.999   -34.282 63.279 1.00 39.02  ? 318 PHE F C   1 
ATOM   15608 O O   . PHE F 1 116 ? 4.244   -34.194 62.074 1.00 40.31  ? 318 PHE F O   1 
ATOM   15609 C CB  . PHE F 1 116 ? 3.778   -32.537 65.088 1.00 37.80  ? 318 PHE F CB  1 
ATOM   15610 C CG  . PHE F 1 116 ? 3.095   -31.495 64.247 1.00 38.71  ? 318 PHE F CG  1 
ATOM   15611 C CD1 . PHE F 1 116 ? 1.854   -31.736 63.688 1.00 38.64  ? 318 PHE F CD1 1 
ATOM   15612 C CD2 . PHE F 1 116 ? 3.701   -30.277 64.007 1.00 38.89  ? 318 PHE F CD2 1 
ATOM   15613 C CE1 . PHE F 1 116 ? 1.229   -30.777 62.918 1.00 38.01  ? 318 PHE F CE1 1 
ATOM   15614 C CE2 . PHE F 1 116 ? 3.082   -29.320 63.233 1.00 39.11  ? 318 PHE F CE2 1 
ATOM   15615 C CZ  . PHE F 1 116 ? 1.848   -29.572 62.688 1.00 39.41  ? 318 PHE F CZ  1 
ATOM   15616 N N   . ASN F 1 117 ? 3.074   -35.100 63.788 1.00 39.10  ? 319 ASN F N   1 
ATOM   15617 C CA  . ASN F 1 117 ? 2.259   -36.015 62.984 1.00 39.52  ? 319 ASN F CA  1 
ATOM   15618 C C   . ASN F 1 117 ? 3.123   -36.899 62.089 1.00 40.03  ? 319 ASN F C   1 
ATOM   15619 O O   . ASN F 1 117 ? 2.886   -37.037 60.888 1.00 42.12  ? 319 ASN F O   1 
ATOM   15620 C CB  . ASN F 1 117 ? 1.224   -35.249 62.162 1.00 38.93  ? 319 ASN F CB  1 
ATOM   15621 C CG  . ASN F 1 117 ? 0.115   -34.678 63.016 1.00 41.44  ? 319 ASN F CG  1 
ATOM   15622 O OD1 . ASN F 1 117 ? -0.151  -35.166 64.112 1.00 40.62  ? 319 ASN F OD1 1 
ATOM   15623 N ND2 . ASN F 1 117 ? -0.540  -33.642 62.518 1.00 42.93  ? 319 ASN F ND2 1 
ATOM   15624 N N   . ILE F 1 118 ? 4.131   -37.522 62.699 1.00 43.06  ? 320 ILE F N   1 
ATOM   15625 C CA  . ILE F 1 118 ? 5.035   -38.389 61.957 1.00 43.47  ? 320 ILE F CA  1 
ATOM   15626 C C   . ILE F 1 118 ? 4.317   -39.676 61.581 1.00 44.47  ? 320 ILE F C   1 
ATOM   15627 O O   . ILE F 1 118 ? 3.692   -40.333 62.424 1.00 45.58  ? 320 ILE F O   1 
ATOM   15628 C CB  . ILE F 1 118 ? 6.296   -38.683 62.784 1.00 39.83  ? 320 ILE F CB  1 
ATOM   15629 C CG1 . ILE F 1 118 ? 6.957   -37.379 63.233 1.00 39.22  ? 320 ILE F CG1 1 
ATOM   15630 C CG2 . ILE F 1 118 ? 7.265   -39.523 61.978 1.00 40.21  ? 320 ILE F CG2 1 
ATOM   15631 C CD1 . ILE F 1 118 ? 7.361   -36.478 62.102 1.00 41.71  ? 320 ILE F CD1 1 
ATOM   15632 N N   . GLN F 1 119 ? 4.402   -40.046 60.306 1.00 45.79  ? 321 GLN F N   1 
ATOM   15633 C CA  . GLN F 1 119 ? 3.778   -41.265 59.807 1.00 46.93  ? 321 GLN F CA  1 
ATOM   15634 C C   . GLN F 1 119 ? 4.809   -42.021 58.989 1.00 47.16  ? 321 GLN F C   1 
ATOM   15635 O O   . GLN F 1 119 ? 5.247   -41.531 57.945 1.00 47.99  ? 321 GLN F O   1 
ATOM   15636 C CB  . GLN F 1 119 ? 2.551   -40.944 58.954 1.00 50.19  ? 321 GLN F CB  1 
ATOM   15637 C CG  . GLN F 1 119 ? 1.459   -40.216 59.701 1.00 52.48  ? 321 GLN F CG  1 
ATOM   15638 C CD  . GLN F 1 119 ? 0.313   -39.811 58.803 1.00 54.79  ? 321 GLN F CD  1 
ATOM   15639 O OE1 . GLN F 1 119 ? 0.463   -39.717 57.586 1.00 53.78  ? 321 GLN F OE1 1 
ATOM   15640 N NE2 . GLN F 1 119 ? -0.833  -39.540 59.404 1.00 53.94  ? 321 GLN F NE2 1 
ATOM   15641 N N   . VAL F 1 120 ? 5.191   -43.208 59.448 1.00 49.99  ? 322 VAL F N   1 
ATOM   15642 C CA  . VAL F 1 120 ? 6.213   -44.015 58.792 1.00 50.47  ? 322 VAL F CA  1 
ATOM   15643 C C   . VAL F 1 120 ? 5.532   -45.180 58.091 1.00 51.11  ? 322 VAL F C   1 
ATOM   15644 O O   . VAL F 1 120 ? 4.813   -45.963 58.723 1.00 51.32  ? 322 VAL F O   1 
ATOM   15645 C CB  . VAL F 1 120 ? 7.269   -44.515 59.790 1.00 50.49  ? 322 VAL F CB  1 
ATOM   15646 C CG1 . VAL F 1 120 ? 8.288   -45.363 59.071 1.00 50.28  ? 322 VAL F CG1 1 
ATOM   15647 C CG2 . VAL F 1 120 ? 7.936   -43.345 60.487 1.00 48.75  ? 322 VAL F CG2 1 
ATOM   15648 N N   . LYS F 1 121 ? 5.762   -45.294 56.787 1.00 52.18  ? 323 LYS F N   1 
ATOM   15649 C CA  . LYS F 1 121 ? 5.135   -46.306 55.954 1.00 54.04  ? 323 LYS F CA  1 
ATOM   15650 C C   . LYS F 1 121 ? 6.147   -47.377 55.575 1.00 55.65  ? 323 LYS F C   1 
ATOM   15651 O O   . LYS F 1 121 ? 7.343   -47.105 55.440 1.00 55.80  ? 323 LYS F O   1 
ATOM   15652 C CB  . LYS F 1 121 ? 4.555   -45.695 54.676 1.00 51.09  ? 323 LYS F CB  1 
ATOM   15653 C CG  . LYS F 1 121 ? 3.564   -44.575 54.905 1.00 52.31  ? 323 LYS F CG  1 
ATOM   15654 C CD  . LYS F 1 121 ? 2.346   -45.055 55.662 1.00 54.30  ? 323 LYS F CD  1 
ATOM   15655 C CE  . LYS F 1 121 ? 1.337   -43.935 55.812 1.00 55.13  ? 323 LYS F CE  1 
ATOM   15656 N NZ  . LYS F 1 121 ? 0.127   -44.361 56.562 1.00 56.90  ? 323 LYS F NZ  1 
ATOM   15657 N N   . GLU F 1 122 ? 5.657   -48.601 55.414 1.00 61.81  ? 324 GLU F N   1 
ATOM   15658 C CA  . GLU F 1 122 ? 6.431   -49.681 54.823 1.00 65.93  ? 324 GLU F CA  1 
ATOM   15659 C C   . GLU F 1 122 ? 5.807   -50.047 53.486 1.00 65.99  ? 324 GLU F C   1 
ATOM   15660 O O   . GLU F 1 122 ? 4.583   -50.007 53.330 1.00 66.27  ? 324 GLU F O   1 
ATOM   15661 C CB  . GLU F 1 122 ? 6.491   -50.912 55.737 1.00 57.02  ? 324 GLU F CB  1 
ATOM   15662 C CG  . GLU F 1 122 ? 5.151   -51.582 56.003 1.00 67.62  ? 324 GLU F CG  1 
ATOM   15663 C CD  . GLU F 1 122 ? 5.264   -52.744 56.971 1.00 74.30  ? 324 GLU F CD  1 
ATOM   15664 O OE1 . GLU F 1 122 ? 6.391   -53.238 57.180 1.00 77.50  ? 324 GLU F OE1 1 
ATOM   15665 O OE2 . GLU F 1 122 ? 4.227   -53.168 57.523 1.00 76.77  ? 324 GLU F OE2 1 
ATOM   15666 N N   . VAL F 1 123 ? 6.652   -50.379 52.515 1.00 71.83  ? 325 VAL F N   1 
ATOM   15667 C CA  . VAL F 1 123 ? 6.169   -50.777 51.200 1.00 73.50  ? 325 VAL F CA  1 
ATOM   15668 C C   . VAL F 1 123 ? 6.635   -52.196 50.916 1.00 75.95  ? 325 VAL F C   1 
ATOM   15669 O O   . VAL F 1 123 ? 7.831   -52.444 50.727 1.00 75.53  ? 325 VAL F O   1 
ATOM   15670 C CB  . VAL F 1 123 ? 6.647   -49.802 50.110 1.00 73.07  ? 325 VAL F CB  1 
ATOM   15671 C CG1 . VAL F 1 123 ? 6.216   -50.283 48.740 1.00 71.91  ? 325 VAL F CG1 1 
ATOM   15672 C CG2 . VAL F 1 123 ? 6.110   -48.410 50.379 1.00 72.40  ? 325 VAL F CG2 1 
ATOM   15673 N N   . THR F 1 124 ? 5.697   -53.137 50.886 1.00 83.41  ? 326 THR F N   1 
ATOM   15674 C CA  . THR F 1 124 ? 6.040   -54.517 50.581 1.00 87.74  ? 326 THR F CA  1 
ATOM   15675 C C   . THR F 1 124 ? 5.585   -54.864 49.172 1.00 90.94  ? 326 THR F C   1 
ATOM   15676 O O   . THR F 1 124 ? 4.388   -54.892 48.877 1.00 90.84  ? 326 THR F O   1 
ATOM   15677 C CB  . THR F 1 124 ? 5.396   -55.470 51.588 1.00 87.49  ? 326 THR F CB  1 
ATOM   15678 O OG1 . THR F 1 124 ? 3.972   -55.332 51.535 1.00 89.30  ? 326 THR F OG1 1 
ATOM   15679 C CG2 . THR F 1 124 ? 5.870   -55.157 52.995 1.00 86.88  ? 326 THR F CG2 1 
ATOM   15680 N N   . ASP F 1 125 ? 6.550   -55.126 48.296 1.00 93.62  ? 327 ASP F N   1 
ATOM   15681 C CA  . ASP F 1 125 ? 6.271   -55.462 46.907 1.00 98.31  ? 327 ASP F CA  1 
ATOM   15682 C C   . ASP F 1 125 ? 6.430   -56.965 46.739 1.00 99.84  ? 327 ASP F C   1 
ATOM   15683 O O   . ASP F 1 125 ? 7.552   -57.481 46.755 1.00 99.76  ? 327 ASP F O   1 
ATOM   15684 C CB  . ASP F 1 125 ? 7.201   -54.703 45.959 1.00 96.21  ? 327 ASP F CB  1 
ATOM   15685 C CG  . ASP F 1 125 ? 6.822   -54.876 44.500 1.00 100.26 ? 327 ASP F CG  1 
ATOM   15686 O OD1 . ASP F 1 125 ? 5.791   -55.523 44.220 1.00 102.04 ? 327 ASP F OD1 1 
ATOM   15687 O OD2 . ASP F 1 125 ? 7.554   -54.361 43.629 1.00 102.29 ? 327 ASP F OD2 1 
ATOM   15688 N N   . ASN F 1 126 ? 5.308   -57.660 46.574 1.00 99.52  ? 328 ASN F N   1 
ATOM   15689 C CA  . ASN F 1 126 ? 5.286   -59.097 46.344 1.00 102.31 ? 328 ASN F CA  1 
ATOM   15690 C C   . ASN F 1 126 ? 4.757   -59.343 44.941 1.00 103.52 ? 328 ASN F C   1 
ATOM   15691 O O   . ASN F 1 126 ? 3.664   -58.878 44.599 1.00 103.39 ? 328 ASN F O   1 
ATOM   15692 C CB  . ASN F 1 126 ? 4.417   -59.813 47.380 1.00 103.19 ? 328 ASN F CB  1 
ATOM   15693 C CG  . ASN F 1 126 ? 5.023   -59.785 48.769 1.00 105.15 ? 328 ASN F CG  1 
ATOM   15694 O OD1 . ASN F 1 126 ? 5.950   -60.534 49.071 1.00 105.51 ? 328 ASN F OD1 1 
ATOM   15695 N ND2 . ASN F 1 126 ? 4.499   -58.916 49.624 1.00 105.70 ? 328 ASN F ND2 1 
ATOM   15696 N N   . ASN F 1 127 ? 5.533   -60.068 44.136 1.00 103.26 ? 329 ASN F N   1 
ATOM   15697 C CA  . ASN F 1 127 ? 5.245   -60.271 42.710 1.00 104.61 ? 329 ASN F CA  1 
ATOM   15698 C C   . ASN F 1 127 ? 5.226   -58.884 42.064 1.00 104.07 ? 329 ASN F C   1 
ATOM   15699 O O   . ASN F 1 127 ? 6.181   -58.118 42.252 1.00 104.44 ? 329 ASN F O   1 
ATOM   15700 C CB  . ASN F 1 127 ? 3.972   -61.097 42.552 1.00 103.25 ? 329 ASN F CB  1 
ATOM   15701 C CG  . ASN F 1 127 ? 3.756   -61.570 41.128 1.00 105.70 ? 329 ASN F CG  1 
ATOM   15702 O OD1 . ASN F 1 127 ? 4.710   -61.794 40.383 1.00 106.86 ? 329 ASN F OD1 1 
ATOM   15703 N ND2 . ASN F 1 127 ? 2.494   -61.724 40.742 1.00 105.79 ? 329 ASN F ND2 1 
ATOM   15704 N N   . GLY F 1 128 ? 4.188   -58.521 41.319 1.00 104.69 ? 330 GLY F N   1 
ATOM   15705 C CA  . GLY F 1 128 ? 4.095   -57.200 40.741 1.00 102.91 ? 330 GLY F CA  1 
ATOM   15706 C C   . GLY F 1 128 ? 3.150   -56.260 41.448 1.00 101.59 ? 330 GLY F C   1 
ATOM   15707 O O   . GLY F 1 128 ? 2.772   -55.230 40.881 1.00 102.01 ? 330 GLY F O   1 
ATOM   15708 N N   . VAL F 1 129 ? 2.754   -56.582 42.676 1.00 104.11 ? 331 VAL F N   1 
ATOM   15709 C CA  . VAL F 1 129 ? 1.801   -55.788 43.441 1.00 100.58 ? 331 VAL F CA  1 
ATOM   15710 C C   . VAL F 1 129 ? 2.500   -55.266 44.687 1.00 98.51  ? 331 VAL F C   1 
ATOM   15711 O O   . VAL F 1 129 ? 3.207   -56.016 45.371 1.00 98.16  ? 331 VAL F O   1 
ATOM   15712 C CB  . VAL F 1 129 ? 0.555   -56.611 43.812 1.00 100.44 ? 331 VAL F CB  1 
ATOM   15713 C CG1 . VAL F 1 129 ? -0.389  -55.788 44.676 1.00 99.16  ? 331 VAL F CG1 1 
ATOM   15714 C CG2 . VAL F 1 129 ? -0.145  -57.099 42.558 1.00 100.06 ? 331 VAL F CG2 1 
ATOM   15715 N N   . LYS F 1 130 ? 2.302   -53.986 44.979 1.00 94.50  ? 332 LYS F N   1 
ATOM   15716 C CA  . LYS F 1 130 ? 2.918   -53.328 46.121 1.00 91.02  ? 332 LYS F CA  1 
ATOM   15717 C C   . LYS F 1 130 ? 1.836   -52.903 47.103 1.00 88.38  ? 332 LYS F C   1 
ATOM   15718 O O   . LYS F 1 130 ? 0.731   -52.531 46.695 1.00 88.67  ? 332 LYS F O   1 
ATOM   15719 C CB  . LYS F 1 130 ? 3.747   -52.128 45.664 1.00 86.37  ? 332 LYS F CB  1 
ATOM   15720 C CG  . LYS F 1 130 ? 2.949   -51.066 44.932 1.00 86.84  ? 332 LYS F CG  1 
ATOM   15721 C CD  . LYS F 1 130 ? 3.860   -49.975 44.408 1.00 87.28  ? 332 LYS F CD  1 
ATOM   15722 C CE  . LYS F 1 130 ? 4.520   -49.213 45.537 1.00 88.10  ? 332 LYS F CE  1 
ATOM   15723 N NZ  . LYS F 1 130 ? 5.425   -48.165 45.002 1.00 87.72  ? 332 LYS F NZ  1 
ATOM   15724 N N   . THR F 1 131 ? 2.152   -52.972 48.392 1.00 83.86  ? 333 THR F N   1 
ATOM   15725 C CA  . THR F 1 131 ? 1.205   -52.683 49.459 1.00 80.87  ? 333 THR F CA  1 
ATOM   15726 C C   . THR F 1 131 ? 1.857   -51.749 50.469 1.00 77.82  ? 333 THR F C   1 
ATOM   15727 O O   . THR F 1 131 ? 3.018   -51.944 50.840 1.00 77.78  ? 333 THR F O   1 
ATOM   15728 C CB  . THR F 1 131 ? 0.746   -53.975 50.142 1.00 79.98  ? 333 THR F CB  1 
ATOM   15729 O OG1 . THR F 1 131 ? 0.104   -54.820 49.182 1.00 80.79  ? 333 THR F OG1 1 
ATOM   15730 C CG2 . THR F 1 131 ? -0.230  -53.675 51.269 1.00 80.14  ? 333 THR F CG2 1 
ATOM   15731 N N   . ILE F 1 132 ? 1.110   -50.741 50.909 1.00 75.00  ? 334 ILE F N   1 
ATOM   15732 C CA  . ILE F 1 132 ? 1.602   -49.747 51.854 1.00 70.80  ? 334 ILE F CA  1 
ATOM   15733 C C   . ILE F 1 132 ? 0.883   -49.944 53.180 1.00 69.23  ? 334 ILE F C   1 
ATOM   15734 O O   . ILE F 1 132 ? -0.351  -50.017 53.220 1.00 69.25  ? 334 ILE F O   1 
ATOM   15735 C CB  . ILE F 1 132 ? 1.388   -48.322 51.321 1.00 66.81  ? 334 ILE F CB  1 
ATOM   15736 C CG1 . ILE F 1 132 ? 2.160   -48.121 50.018 1.00 65.66  ? 334 ILE F CG1 1 
ATOM   15737 C CG2 . ILE F 1 132 ? 1.834   -47.303 52.352 1.00 66.30  ? 334 ILE F CG2 1 
ATOM   15738 C CD1 . ILE F 1 132 ? 1.811   -46.842 49.296 1.00 66.59  ? 334 ILE F CD1 1 
ATOM   15739 N N   . ALA F 1 133 ? 1.648   -50.029 54.265 1.00 65.44  ? 335 ALA F N   1 
ATOM   15740 C CA  . ALA F 1 133 ? 1.066   -50.220 55.584 1.00 64.65  ? 335 ALA F CA  1 
ATOM   15741 C C   . ALA F 1 133 ? 1.873   -49.445 56.613 1.00 65.10  ? 335 ALA F C   1 
ATOM   15742 O O   . ALA F 1 133 ? 3.074   -49.222 56.444 1.00 66.74  ? 335 ALA F O   1 
ATOM   15743 C CB  . ALA F 1 133 ? 1.008   -51.703 55.967 1.00 64.02  ? 335 ALA F CB  1 
ATOM   15744 N N   . ASN F 1 134 ? 1.197   -49.033 57.680 1.00 63.28  ? 336 ASN F N   1 
ATOM   15745 C CA  . ASN F 1 134 ? 1.864   -48.310 58.750 1.00 64.05  ? 336 ASN F CA  1 
ATOM   15746 C C   . ASN F 1 134 ? 2.785   -49.239 59.526 1.00 63.99  ? 336 ASN F C   1 
ATOM   15747 O O   . ASN F 1 134 ? 2.375   -50.313 59.974 1.00 63.81  ? 336 ASN F O   1 
ATOM   15748 C CB  . ASN F 1 134 ? 0.837   -47.698 59.701 1.00 61.65  ? 336 ASN F CB  1 
ATOM   15749 C CG  . ASN F 1 134 ? 0.062   -46.564 59.074 1.00 63.75  ? 336 ASN F CG  1 
ATOM   15750 O OD1 . ASN F 1 134 ? 0.525   -45.931 58.130 1.00 66.79  ? 336 ASN F OD1 1 
ATOM   15751 N ND2 . ASN F 1 134 ? -1.125  -46.300 59.598 1.00 63.84  ? 336 ASN F ND2 1 
ATOM   15752 N N   . ASN F 1 135 ? 4.033   -48.823 59.687 1.00 60.63  ? 337 ASN F N   1 
ATOM   15753 C CA  . ASN F 1 135 ? 4.958   -49.477 60.606 1.00 60.53  ? 337 ASN F CA  1 
ATOM   15754 C C   . ASN F 1 135 ? 5.012   -48.574 61.831 1.00 59.56  ? 337 ASN F C   1 
ATOM   15755 O O   . ASN F 1 135 ? 5.615   -47.499 61.795 1.00 60.52  ? 337 ASN F O   1 
ATOM   15756 C CB  . ASN F 1 135 ? 6.329   -49.673 59.966 1.00 59.31  ? 337 ASN F CB  1 
ATOM   15757 C CG  . ASN F 1 135 ? 7.254   -50.534 60.807 1.00 63.32  ? 337 ASN F CG  1 
ATOM   15758 O OD1 . ASN F 1 135 ? 7.058   -50.693 62.010 1.00 65.03  ? 337 ASN F OD1 1 
ATOM   15759 N ND2 . ASN F 1 135 ? 8.273   -51.097 60.169 1.00 66.98  ? 337 ASN F ND2 1 
ATOM   15760 N N   . LEU F 1 136 ? 4.384   -49.018 62.919 1.00 57.49  ? 338 LEU F N   1 
ATOM   15761 C CA  . LEU F 1 136 ? 4.203   -48.155 64.077 1.00 55.98  ? 338 LEU F CA  1 
ATOM   15762 C C   . LEU F 1 136 ? 5.437   -48.076 64.961 1.00 56.49  ? 338 LEU F C   1 
ATOM   15763 O O   . LEU F 1 136 ? 5.650   -47.047 65.610 1.00 56.80  ? 338 LEU F O   1 
ATOM   15764 C CB  . LEU F 1 136 ? 3.010   -48.633 64.906 1.00 61.75  ? 338 LEU F CB  1 
ATOM   15765 C CG  . LEU F 1 136 ? 1.654   -48.594 64.198 1.00 60.92  ? 338 LEU F CG  1 
ATOM   15766 C CD1 . LEU F 1 136 ? 0.559   -49.169 65.083 1.00 56.88  ? 338 LEU F CD1 1 
ATOM   15767 C CD2 . LEU F 1 136 ? 1.315   -47.182 63.764 1.00 60.12  ? 338 LEU F CD2 1 
ATOM   15768 N N   . THR F 1 137 ? 6.247   -49.129 65.007 1.00 56.40  ? 339 THR F N   1 
ATOM   15769 C CA  . THR F 1 137 ? 7.402   -49.183 65.890 1.00 56.52  ? 339 THR F CA  1 
ATOM   15770 C C   . THR F 1 137 ? 8.596   -48.409 65.355 1.00 55.56  ? 339 THR F C   1 
ATOM   15771 O O   . THR F 1 137 ? 9.543   -48.160 66.107 1.00 55.88  ? 339 THR F O   1 
ATOM   15772 C CB  . THR F 1 137 ? 7.804   -50.638 66.138 1.00 56.30  ? 339 THR F CB  1 
ATOM   15773 O OG1 . THR F 1 137 ? 8.128   -51.263 64.890 1.00 58.57  ? 339 THR F OG1 1 
ATOM   15774 C CG2 . THR F 1 137 ? 6.663   -51.394 66.797 1.00 56.23  ? 339 THR F CG2 1 
ATOM   15775 N N   . SER F 1 138 ? 8.570   -48.016 64.086 1.00 53.46  ? 340 SER F N   1 
ATOM   15776 C CA  . SER F 1 138 ? 9.681   -47.306 63.479 1.00 52.98  ? 340 SER F CA  1 
ATOM   15777 C C   . SER F 1 138 ? 9.845   -45.923 64.097 1.00 52.21  ? 340 SER F C   1 
ATOM   15778 O O   . SER F 1 138 ? 8.928   -45.371 64.711 1.00 51.74  ? 340 SER F O   1 
ATOM   15779 C CB  . SER F 1 138 ? 9.475   -47.177 61.973 1.00 51.78  ? 340 SER F CB  1 
ATOM   15780 O OG  . SER F 1 138 ? 9.482   -48.445 61.345 1.00 58.24  ? 340 SER F OG  1 
ATOM   15781 N N   . THR F 1 139 ? 11.039  -45.368 63.927 1.00 48.46  ? 341 THR F N   1 
ATOM   15782 C CA  . THR F 1 139 ? 11.387  -44.057 64.443 1.00 48.82  ? 341 THR F CA  1 
ATOM   15783 C C   . THR F 1 139 ? 11.945  -43.194 63.321 1.00 47.87  ? 341 THR F C   1 
ATOM   15784 O O   . THR F 1 139 ? 12.278  -43.682 62.238 1.00 47.54  ? 341 THR F O   1 
ATOM   15785 C CB  . THR F 1 139 ? 12.422  -44.147 65.565 1.00 46.05  ? 341 THR F CB  1 
ATOM   15786 O OG1 . THR F 1 139 ? 13.609  -44.764 65.059 1.00 46.68  ? 341 THR F OG1 1 
ATOM   15787 C CG2 . THR F 1 139 ? 11.891  -44.963 66.721 1.00 48.84  ? 341 THR F CG2 1 
ATOM   15788 N N   . VAL F 1 140 ? 12.036  -41.896 63.594 1.00 45.96  ? 342 VAL F N   1 
ATOM   15789 C CA  . VAL F 1 140 ? 12.638  -40.930 62.685 1.00 45.06  ? 342 VAL F CA  1 
ATOM   15790 C C   . VAL F 1 140 ? 13.683  -40.137 63.457 1.00 44.52  ? 342 VAL F C   1 
ATOM   15791 O O   . VAL F 1 140 ? 13.420  -39.662 64.567 1.00 45.14  ? 342 VAL F O   1 
ATOM   15792 C CB  . VAL F 1 140 ? 11.579  -39.995 62.062 1.00 42.07  ? 342 VAL F CB  1 
ATOM   15793 C CG1 . VAL F 1 140 ? 12.239  -38.922 61.226 1.00 44.72  ? 342 VAL F CG1 1 
ATOM   15794 C CG2 . VAL F 1 140 ? 10.615  -40.791 61.210 1.00 43.49  ? 342 VAL F CG2 1 
ATOM   15795 N N   . GLN F 1 141 ? 14.871  -40.012 62.876 1.00 42.07  ? 343 GLN F N   1 
ATOM   15796 C CA  . GLN F 1 141 ? 15.966  -39.265 63.475 1.00 41.82  ? 343 GLN F CA  1 
ATOM   15797 C C   . GLN F 1 141 ? 15.958  -37.829 62.975 1.00 41.06  ? 343 GLN F C   1 
ATOM   15798 O O   . GLN F 1 141 ? 15.847  -37.583 61.771 1.00 41.80  ? 343 GLN F O   1 
ATOM   15799 C CB  . GLN F 1 141 ? 17.311  -39.910 63.144 1.00 44.11  ? 343 GLN F CB  1 
ATOM   15800 C CG  . GLN F 1 141 ? 17.538  -41.265 63.775 1.00 46.38  ? 343 GLN F CG  1 
ATOM   15801 C CD  . GLN F 1 141 ? 18.853  -41.877 63.345 1.00 50.24  ? 343 GLN F CD  1 
ATOM   15802 O OE1 . GLN F 1 141 ? 19.372  -41.566 62.273 1.00 53.00  ? 343 GLN F OE1 1 
ATOM   15803 N NE2 . GLN F 1 141 ? 19.407  -42.742 64.183 1.00 51.49  ? 343 GLN F NE2 1 
ATOM   15804 N N   . VAL F 1 142 ? 16.080  -36.885 63.902 1.00 38.14  ? 344 VAL F N   1 
ATOM   15805 C CA  . VAL F 1 142 ? 16.147  -35.468 63.564 1.00 38.11  ? 344 VAL F CA  1 
ATOM   15806 C C   . VAL F 1 142 ? 17.098  -34.774 64.529 1.00 38.98  ? 344 VAL F C   1 
ATOM   15807 O O   . VAL F 1 142 ? 17.072  -35.029 65.737 1.00 39.88  ? 344 VAL F O   1 
ATOM   15808 C CB  . VAL F 1 142 ? 14.745  -34.819 63.579 1.00 37.61  ? 344 VAL F CB  1 
ATOM   15809 C CG1 . VAL F 1 142 ? 14.102  -34.932 64.949 1.00 36.84  ? 344 VAL F CG1 1 
ATOM   15810 C CG2 . VAL F 1 142 ? 14.820  -33.368 63.140 1.00 40.18  ? 344 VAL F CG2 1 
ATOM   15811 N N   . PHE F 1 143 ? 17.964  -33.920 63.989 1.00 40.84  ? 345 PHE F N   1 
ATOM   15812 C CA  . PHE F 1 143 ? 18.809  -33.077 64.821 1.00 41.27  ? 345 PHE F CA  1 
ATOM   15813 C C   . PHE F 1 143 ? 19.136  -31.807 64.055 1.00 42.16  ? 345 PHE F C   1 
ATOM   15814 O O   . PHE F 1 143 ? 19.238  -31.809 62.826 1.00 42.63  ? 345 PHE F O   1 
ATOM   15815 C CB  . PHE F 1 143 ? 20.103  -33.786 65.247 1.00 39.42  ? 345 PHE F CB  1 
ATOM   15816 C CG  . PHE F 1 143 ? 21.081  -34.022 64.125 1.00 40.08  ? 345 PHE F CG  1 
ATOM   15817 C CD1 . PHE F 1 143 ? 22.091  -33.109 63.871 1.00 39.46  ? 345 PHE F CD1 1 
ATOM   15818 C CD2 . PHE F 1 143 ? 20.998  -35.150 63.332 1.00 40.94  ? 345 PHE F CD2 1 
ATOM   15819 C CE1 . PHE F 1 143 ? 22.995  -33.315 62.854 1.00 39.75  ? 345 PHE F CE1 1 
ATOM   15820 C CE2 . PHE F 1 143 ? 21.901  -35.360 62.309 1.00 41.02  ? 345 PHE F CE2 1 
ATOM   15821 C CZ  . PHE F 1 143 ? 22.900  -34.439 62.071 1.00 40.54  ? 345 PHE F CZ  1 
ATOM   15822 N N   . THR F 1 144 ? 19.304  -30.722 64.797 1.00 42.58  ? 346 THR F N   1 
ATOM   15823 C CA  . THR F 1 144 ? 19.703  -29.447 64.227 1.00 44.72  ? 346 THR F CA  1 
ATOM   15824 C C   . THR F 1 144 ? 21.101  -29.084 64.700 1.00 46.78  ? 346 THR F C   1 
ATOM   15825 O O   . THR F 1 144 ? 21.513  -29.435 65.809 1.00 46.87  ? 346 THR F O   1 
ATOM   15826 C CB  . THR F 1 144 ? 18.724  -28.338 64.608 1.00 41.72  ? 346 THR F CB  1 
ATOM   15827 O OG1 . THR F 1 144 ? 18.661  -28.220 66.034 1.00 44.78  ? 346 THR F OG1 1 
ATOM   15828 C CG2 . THR F 1 144 ? 17.348  -28.653 64.067 1.00 41.45  ? 346 THR F CG2 1 
ATOM   15829 N N   . ASP F 1 145 ? 21.828  -28.366 63.852 1.00 45.45  ? 347 ASP F N   1 
ATOM   15830 C CA  . ASP F 1 145 ? 23.205  -27.986 64.144 1.00 48.85  ? 347 ASP F CA  1 
ATOM   15831 C C   . ASP F 1 145 ? 23.177  -26.540 64.620 1.00 49.09  ? 347 ASP F C   1 
ATOM   15832 O O   . ASP F 1 145 ? 23.030  -25.607 63.831 1.00 48.93  ? 347 ASP F O   1 
ATOM   15833 C CB  . ASP F 1 145 ? 24.075  -28.163 62.904 1.00 44.47  ? 347 ASP F CB  1 
ATOM   15834 C CG  . ASP F 1 145 ? 25.539  -27.898 63.171 1.00 50.03  ? 347 ASP F CG  1 
ATOM   15835 O OD1 . ASP F 1 145 ? 25.906  -27.660 64.339 1.00 51.05  ? 347 ASP F OD1 1 
ATOM   15836 O OD2 . ASP F 1 145 ? 26.328  -27.928 62.205 1.00 52.79  ? 347 ASP F OD2 1 
ATOM   15837 N N   . SER F 1 146 ? 23.338  -26.355 65.927 1.00 51.12  ? 348 SER F N   1 
ATOM   15838 C CA  . SER F 1 146 ? 23.438  -25.024 66.498 1.00 51.16  ? 348 SER F CA  1 
ATOM   15839 C C   . SER F 1 146 ? 24.876  -24.597 66.737 1.00 51.63  ? 348 SER F C   1 
ATOM   15840 O O   . SER F 1 146 ? 25.111  -23.445 67.112 1.00 51.57  ? 348 SER F O   1 
ATOM   15841 C CB  . SER F 1 146 ? 22.655  -24.954 67.814 1.00 56.10  ? 348 SER F CB  1 
ATOM   15842 O OG  . SER F 1 146 ? 23.208  -25.831 68.778 1.00 59.67  ? 348 SER F OG  1 
ATOM   15843 N N   . ASP F 1 147 ? 25.835  -25.494 66.533 1.00 50.82  ? 349 ASP F N   1 
ATOM   15844 C CA  . ASP F 1 147 ? 27.247  -25.162 66.599 1.00 51.26  ? 349 ASP F CA  1 
ATOM   15845 C C   . ASP F 1 147 ? 27.847  -24.919 65.224 1.00 49.14  ? 349 ASP F C   1 
ATOM   15846 O O   . ASP F 1 147 ? 29.028  -24.571 65.130 1.00 48.83  ? 349 ASP F O   1 
ATOM   15847 C CB  . ASP F 1 147 ? 28.013  -26.276 67.316 1.00 52.04  ? 349 ASP F CB  1 
ATOM   15848 C CG  . ASP F 1 147 ? 27.644  -26.381 68.781 1.00 57.91  ? 349 ASP F CG  1 
ATOM   15849 O OD1 . ASP F 1 147 ? 27.039  -25.428 69.313 1.00 61.16  ? 349 ASP F OD1 1 
ATOM   15850 O OD2 . ASP F 1 147 ? 27.955  -27.418 69.402 1.00 61.82  ? 349 ASP F OD2 1 
ATOM   15851 N N   . TYR F 1 148 ? 27.059  -25.098 64.163 1.00 45.59  ? 350 TYR F N   1 
ATOM   15852 C CA  . TYR F 1 148 ? 27.490  -24.835 62.791 1.00 43.61  ? 350 TYR F CA  1 
ATOM   15853 C C   . TYR F 1 148 ? 28.723  -25.660 62.436 1.00 43.01  ? 350 TYR F C   1 
ATOM   15854 O O   . TYR F 1 148 ? 29.636  -25.190 61.755 1.00 43.23  ? 350 TYR F O   1 
ATOM   15855 C CB  . TYR F 1 148 ? 27.734  -23.341 62.578 1.00 40.42  ? 350 TYR F CB  1 
ATOM   15856 C CG  . TYR F 1 148 ? 26.503  -22.521 62.875 1.00 40.51  ? 350 TYR F CG  1 
ATOM   15857 C CD1 . TYR F 1 148 ? 25.544  -22.292 61.903 1.00 41.21  ? 350 TYR F CD1 1 
ATOM   15858 C CD2 . TYR F 1 148 ? 26.284  -22.005 64.144 1.00 39.24  ? 350 TYR F CD2 1 
ATOM   15859 C CE1 . TYR F 1 148 ? 24.413  -21.558 62.181 1.00 41.10  ? 350 TYR F CE1 1 
ATOM   15860 C CE2 . TYR F 1 148 ? 25.154  -21.270 64.431 1.00 39.16  ? 350 TYR F CE2 1 
ATOM   15861 C CZ  . TYR F 1 148 ? 24.223  -21.050 63.446 1.00 40.79  ? 350 TYR F CZ  1 
ATOM   15862 O OH  . TYR F 1 148 ? 23.096  -20.316 63.733 1.00 42.48  ? 350 TYR F OH  1 
ATOM   15863 N N   . GLN F 1 149 ? 28.747  -26.904 62.909 1.00 44.05  ? 351 GLN F N   1 
ATOM   15864 C CA  . GLN F 1 149 ? 29.889  -27.784 62.715 1.00 43.88  ? 351 GLN F CA  1 
ATOM   15865 C C   . GLN F 1 149 ? 29.845  -28.547 61.400 1.00 43.50  ? 351 GLN F C   1 
ATOM   15866 O O   . GLN F 1 149 ? 30.880  -29.065 60.969 1.00 45.59  ? 351 GLN F O   1 
ATOM   15867 C CB  . GLN F 1 149 ? 29.982  -28.764 63.885 1.00 44.15  ? 351 GLN F CB  1 
ATOM   15868 C CG  . GLN F 1 149 ? 30.294  -28.080 65.204 1.00 44.98  ? 351 GLN F CG  1 
ATOM   15869 C CD  . GLN F 1 149 ? 30.224  -29.022 66.385 1.00 47.34  ? 351 GLN F CD  1 
ATOM   15870 O OE1 . GLN F 1 149 ? 29.526  -30.032 66.346 1.00 49.68  ? 351 GLN F OE1 1 
ATOM   15871 N NE2 . GLN F 1 149 ? 30.949  -28.694 67.446 1.00 47.05  ? 351 GLN F NE2 1 
ATOM   15872 N N   . LEU F 1 150 ? 28.692  -28.629 60.763 1.00 42.58  ? 352 LEU F N   1 
ATOM   15873 C CA  . LEU F 1 150 ? 28.552  -29.243 59.454 1.00 41.23  ? 352 LEU F CA  1 
ATOM   15874 C C   . LEU F 1 150 ? 28.710  -28.207 58.353 1.00 41.25  ? 352 LEU F C   1 
ATOM   15875 O O   . LEU F 1 150 ? 28.528  -27.008 58.582 1.00 42.19  ? 352 LEU F O   1 
ATOM   15876 C CB  . LEU F 1 150 ? 27.191  -29.923 59.338 1.00 41.27  ? 352 LEU F CB  1 
ATOM   15877 C CG  . LEU F 1 150 ? 26.978  -31.173 60.186 1.00 41.95  ? 352 LEU F CG  1 
ATOM   15878 C CD1 . LEU F 1 150 ? 25.533  -31.607 60.121 1.00 41.44  ? 352 LEU F CD1 1 
ATOM   15879 C CD2 . LEU F 1 150 ? 27.878  -32.276 59.678 1.00 40.22  ? 352 LEU F CD2 1 
ATOM   15880 N N   . PRO F 1 151 ? 29.068  -28.638 57.145 1.00 39.79  ? 353 PRO F N   1 
ATOM   15881 C CA  . PRO F 1 151 ? 29.028  -27.723 56.000 1.00 38.77  ? 353 PRO F CA  1 
ATOM   15882 C C   . PRO F 1 151 ? 27.629  -27.167 55.800 1.00 39.24  ? 353 PRO F C   1 
ATOM   15883 O O   . PRO F 1 151 ? 26.635  -27.890 55.886 1.00 39.10  ? 353 PRO F O   1 
ATOM   15884 C CB  . PRO F 1 151 ? 29.455  -28.611 54.831 1.00 38.63  ? 353 PRO F CB  1 
ATOM   15885 C CG  . PRO F 1 151 ? 30.313  -29.646 55.459 1.00 38.21  ? 353 PRO F CG  1 
ATOM   15886 C CD  . PRO F 1 151 ? 29.696  -29.923 56.797 1.00 38.32  ? 353 PRO F CD  1 
ATOM   15887 N N   . TYR F 1 152 ? 27.556  -25.868 55.532 1.00 34.81  ? 354 TYR F N   1 
ATOM   15888 C CA  . TYR F 1 152 ? 26.287  -25.153 55.465 1.00 35.40  ? 354 TYR F CA  1 
ATOM   15889 C C   . TYR F 1 152 ? 25.922  -24.960 53.998 1.00 36.83  ? 354 TYR F C   1 
ATOM   15890 O O   . TYR F 1 152 ? 26.539  -24.151 53.300 1.00 38.31  ? 354 TYR F O   1 
ATOM   15891 C CB  . TYR F 1 152 ? 26.397  -23.817 56.191 1.00 34.00  ? 354 TYR F CB  1 
ATOM   15892 C CG  . TYR F 1 152 ? 25.117  -23.023 56.236 1.00 35.00  ? 354 TYR F CG  1 
ATOM   15893 C CD1 . TYR F 1 152 ? 24.155  -23.278 57.202 1.00 35.01  ? 354 TYR F CD1 1 
ATOM   15894 C CD2 . TYR F 1 152 ? 24.864  -22.028 55.307 1.00 34.47  ? 354 TYR F CD2 1 
ATOM   15895 C CE1 . TYR F 1 152 ? 22.986  -22.556 57.247 1.00 36.14  ? 354 TYR F CE1 1 
ATOM   15896 C CE2 . TYR F 1 152 ? 23.699  -21.302 55.343 1.00 35.77  ? 354 TYR F CE2 1 
ATOM   15897 C CZ  . TYR F 1 152 ? 22.764  -21.569 56.316 1.00 37.48  ? 354 TYR F CZ  1 
ATOM   15898 O OH  . TYR F 1 152 ? 21.596  -20.849 56.353 1.00 38.32  ? 354 TYR F OH  1 
ATOM   15899 N N   . VAL F 1 153 ? 24.917  -25.706 53.534 1.00 35.48  ? 355 VAL F N   1 
ATOM   15900 C CA  . VAL F 1 153 ? 24.514  -25.693 52.132 1.00 35.58  ? 355 VAL F CA  1 
ATOM   15901 C C   . VAL F 1 153 ? 23.304  -24.812 51.870 1.00 36.92  ? 355 VAL F C   1 
ATOM   15902 O O   . VAL F 1 153 ? 22.844  -24.737 50.724 1.00 36.81  ? 355 VAL F O   1 
ATOM   15903 C CB  . VAL F 1 153 ? 24.239  -27.122 51.631 1.00 36.53  ? 355 VAL F CB  1 
ATOM   15904 C CG1 . VAL F 1 153 ? 25.504  -27.955 51.704 1.00 38.33  ? 355 VAL F CG1 1 
ATOM   15905 C CG2 . VAL F 1 153 ? 23.123  -27.760 52.440 1.00 35.36  ? 355 VAL F CG2 1 
ATOM   15906 N N   . LEU F 1 154 ? 22.767  -24.149 52.893 1.00 33.62  ? 356 LEU F N   1 
ATOM   15907 C CA  . LEU F 1 154 ? 21.502  -23.440 52.741 1.00 35.10  ? 356 LEU F CA  1 
ATOM   15908 C C   . LEU F 1 154 ? 21.653  -22.070 52.099 1.00 37.52  ? 356 LEU F C   1 
ATOM   15909 O O   . LEU F 1 154 ? 20.640  -21.465 51.735 1.00 39.67  ? 356 LEU F O   1 
ATOM   15910 C CB  . LEU F 1 154 ? 20.827  -23.292 54.103 1.00 38.70  ? 356 LEU F CB  1 
ATOM   15911 C CG  . LEU F 1 154 ? 20.449  -24.599 54.795 1.00 37.44  ? 356 LEU F CG  1 
ATOM   15912 C CD1 . LEU F 1 154 ? 19.891  -24.323 56.176 1.00 37.09  ? 356 LEU F CD1 1 
ATOM   15913 C CD2 . LEU F 1 154 ? 19.458  -25.369 53.953 1.00 36.53  ? 356 LEU F CD2 1 
ATOM   15914 N N   . GLY F 1 155 ? 22.874  -21.564 51.995 1.00 32.58  ? 357 GLY F N   1 
ATOM   15915 C CA  . GLY F 1 155 ? 23.086  -20.252 51.419 1.00 34.34  ? 357 GLY F CA  1 
ATOM   15916 C C   . GLY F 1 155 ? 23.571  -20.296 49.991 1.00 33.65  ? 357 GLY F C   1 
ATOM   15917 O O   . GLY F 1 155 ? 24.252  -19.384 49.536 1.00 32.48  ? 357 GLY F O   1 
ATOM   15918 N N   . SER F 1 156 ? 23.238  -21.371 49.291 1.00 31.71  ? 358 SER F N   1 
ATOM   15919 C CA  . SER F 1 156 ? 23.646  -21.545 47.906 1.00 29.03  ? 358 SER F CA  1 
ATOM   15920 C C   . SER F 1 156 ? 22.507  -21.498 46.900 1.00 28.56  ? 358 SER F C   1 
ATOM   15921 O O   . SER F 1 156 ? 22.662  -21.980 45.784 1.00 28.16  ? 358 SER F O   1 
ATOM   15922 C CB  . SER F 1 156 ? 24.452  -22.829 47.742 1.00 33.52  ? 358 SER F CB  1 
ATOM   15923 O OG  . SER F 1 156 ? 25.745  -22.675 48.296 1.00 35.51  ? 358 SER F OG  1 
ATOM   15924 N N   . ALA F 1 157 ? 21.363  -20.970 47.324 1.00 27.01  ? 359 ALA F N   1 
ATOM   15925 C CA  . ALA F 1 157 ? 20.163  -20.833 46.494 1.00 25.52  ? 359 ALA F CA  1 
ATOM   15926 C C   . ALA F 1 157 ? 19.648  -22.136 45.903 1.00 25.61  ? 359 ALA F C   1 
ATOM   15927 O O   . ALA F 1 157 ? 19.217  -22.175 44.762 1.00 25.27  ? 359 ALA F O   1 
ATOM   15928 C CB  . ALA F 1 157 ? 20.353  -19.786 45.406 1.00 20.02  ? 359 ALA F CB  1 
ATOM   15929 N N   . HIS F 1 158 ? 19.708  -23.203 46.686 1.00 26.27  ? 360 HIS F N   1 
ATOM   15930 C CA  . HIS F 1 158 ? 19.245  -24.513 46.255 1.00 27.11  ? 360 HIS F CA  1 
ATOM   15931 C C   . HIS F 1 158 ? 17.754  -24.715 46.383 1.00 29.14  ? 360 HIS F C   1 
ATOM   15932 O O   . HIS F 1 158 ? 17.067  -23.961 47.054 1.00 29.92  ? 360 HIS F O   1 
ATOM   15933 C CB  . HIS F 1 158 ? 19.972  -25.621 47.002 1.00 28.88  ? 360 HIS F CB  1 
ATOM   15934 C CG  . HIS F 1 158 ? 21.401  -25.765 46.603 1.00 30.67  ? 360 HIS F CG  1 
ATOM   15935 N ND1 . HIS F 1 158 ? 21.791  -25.921 45.293 1.00 30.79  ? 360 HIS F ND1 1 
ATOM   15936 C CD2 . HIS F 1 158 ? 22.534  -25.764 47.337 1.00 31.93  ? 360 HIS F CD2 1 
ATOM   15937 C CE1 . HIS F 1 158 ? 23.105  -26.014 45.236 1.00 31.72  ? 360 HIS F CE1 1 
ATOM   15938 N NE2 . HIS F 1 158 ? 23.580  -25.920 46.464 1.00 32.46  ? 360 HIS F NE2 1 
ATOM   15939 N N   . GLU F 1 159 ? 17.277  -25.768 45.735 1.00 28.69  ? 361 GLU F N   1 
ATOM   15940 C CA  . GLU F 1 159 ? 15.880  -26.176 45.731 1.00 30.83  ? 361 GLU F CA  1 
ATOM   15941 C C   . GLU F 1 159 ? 15.539  -27.019 46.968 1.00 30.49  ? 361 GLU F C   1 
ATOM   15942 O O   . GLU F 1 159 ? 16.359  -27.201 47.860 1.00 30.53  ? 361 GLU F O   1 
ATOM   15943 C CB  . GLU F 1 159 ? 15.609  -27.005 44.483 1.00 27.32  ? 361 GLU F CB  1 
ATOM   15944 C CG  . GLU F 1 159 ? 14.250  -26.776 43.867 1.00 37.29  ? 361 GLU F CG  1 
ATOM   15945 C CD  . GLU F 1 159 ? 14.308  -25.792 42.729 1.00 41.97  ? 361 GLU F CD  1 
ATOM   15946 O OE1 . GLU F 1 159 ? 15.250  -25.891 41.923 1.00 43.99  ? 361 GLU F OE1 1 
ATOM   15947 O OE2 . GLU F 1 159 ? 13.414  -24.933 42.635 1.00 43.84  ? 361 GLU F OE2 1 
ATOM   15948 N N   . GLY F 1 160 ? 14.319  -27.532 47.024 1.00 30.66  ? 362 GLY F N   1 
ATOM   15949 C CA  . GLY F 1 160 ? 13.907  -28.357 48.143 1.00 30.04  ? 362 GLY F CA  1 
ATOM   15950 C C   . GLY F 1 160 ? 13.274  -27.628 49.304 1.00 29.75  ? 362 GLY F C   1 
ATOM   15951 O O   . GLY F 1 160 ? 12.959  -28.229 50.323 1.00 29.69  ? 362 GLY F O   1 
ATOM   15952 N N   . CYS F 1 161 ? 13.074  -26.327 49.146 1.00 32.41  ? 363 CYS F N   1 
ATOM   15953 C CA  . CYS F 1 161 ? 12.440  -25.498 50.169 1.00 32.59  ? 363 CYS F CA  1 
ATOM   15954 C C   . CYS F 1 161 ? 10.931  -25.736 50.202 1.00 30.14  ? 363 CYS F C   1 
ATOM   15955 O O   . CYS F 1 161 ? 10.361  -26.277 49.259 1.00 29.62  ? 363 CYS F O   1 
ATOM   15956 C CB  . CYS F 1 161 ? 12.743  -24.017 49.936 1.00 31.38  ? 363 CYS F CB  1 
ATOM   15957 S SG  . CYS F 1 161 ? 14.460  -23.528 50.231 1.00 40.46  ? 363 CYS F SG  1 
ATOM   15958 N N   . LEU F 1 162 ? 10.275  -25.319 51.279 1.00 26.44  ? 364 LEU F N   1 
ATOM   15959 C CA  . LEU F 1 162 ? 8.836   -25.504 51.390 1.00 25.34  ? 364 LEU F CA  1 
ATOM   15960 C C   . LEU F 1 162 ? 8.144   -24.802 50.234 1.00 25.00  ? 364 LEU F C   1 
ATOM   15961 O O   . LEU F 1 162 ? 8.478   -23.677 49.896 1.00 25.05  ? 364 LEU F O   1 
ATOM   15962 C CB  . LEU F 1 162 ? 8.328   -24.906 52.695 1.00 23.96  ? 364 LEU F CB  1 
ATOM   15963 C CG  . LEU F 1 162 ? 8.447   -25.702 53.988 1.00 24.69  ? 364 LEU F CG  1 
ATOM   15964 C CD1 . LEU F 1 162 ? 9.896   -25.994 54.320 1.00 24.14  ? 364 LEU F CD1 1 
ATOM   15965 C CD2 . LEU F 1 162 ? 7.787   -24.930 55.117 1.00 23.43  ? 364 LEU F CD2 1 
ATOM   15966 N N   . PRO F 1 163 ? 7.139   -25.455 49.645 1.00 23.99  ? 365 PRO F N   1 
ATOM   15967 C CA  . PRO F 1 163 ? 6.426   -24.891 48.498 1.00 23.13  ? 365 PRO F CA  1 
ATOM   15968 C C   . PRO F 1 163 ? 5.680   -23.623 48.865 1.00 22.39  ? 365 PRO F C   1 
ATOM   15969 O O   . PRO F 1 163 ? 5.211   -23.499 49.989 1.00 22.52  ? 365 PRO F O   1 
ATOM   15970 C CB  . PRO F 1 163 ? 5.446   -25.997 48.120 1.00 23.87  ? 365 PRO F CB  1 
ATOM   15971 C CG  . PRO F 1 163 ? 5.245   -26.765 49.374 1.00 24.36  ? 365 PRO F CG  1 
ATOM   15972 C CD  . PRO F 1 163 ? 6.552   -26.725 50.094 1.00 23.55  ? 365 PRO F CD  1 
ATOM   15973 N N   . PRO F 1 164 ? 5.582   -22.676 47.927 1.00 19.48  ? 366 PRO F N   1 
ATOM   15974 C CA  . PRO F 1 164 ? 4.886   -21.425 48.221 1.00 19.03  ? 366 PRO F CA  1 
ATOM   15975 C C   . PRO F 1 164 ? 3.422   -21.653 48.560 1.00 19.43  ? 366 PRO F C   1 
ATOM   15976 O O   . PRO F 1 164 ? 2.929   -21.047 49.500 1.00 19.59  ? 366 PRO F O   1 
ATOM   15977 C CB  . PRO F 1 164 ? 5.012   -20.635 46.918 1.00 15.72  ? 366 PRO F CB  1 
ATOM   15978 C CG  . PRO F 1 164 ? 5.423   -21.614 45.883 1.00 15.80  ? 366 PRO F CG  1 
ATOM   15979 C CD  . PRO F 1 164 ? 6.184   -22.681 46.588 1.00 16.02  ? 366 PRO F CD  1 
ATOM   15980 N N   . PHE F 1 165 ? 2.749   -22.532 47.829 1.00 21.37  ? 367 PHE F N   1 
ATOM   15981 C CA  . PHE F 1 165 ? 1.339   -22.826 48.080 1.00 22.31  ? 367 PHE F CA  1 
ATOM   15982 C C   . PHE F 1 165 ? 1.202   -23.821 49.231 1.00 23.29  ? 367 PHE F C   1 
ATOM   15983 O O   . PHE F 1 165 ? 1.879   -24.839 49.252 1.00 23.12  ? 367 PHE F O   1 
ATOM   15984 C CB  . PHE F 1 165 ? 0.686   -23.345 46.812 1.00 17.62  ? 367 PHE F CB  1 
ATOM   15985 C CG  . PHE F 1 165 ? -0.797  -23.259 46.831 1.00 18.94  ? 367 PHE F CG  1 
ATOM   15986 C CD1 . PHE F 1 165 ? -1.423  -22.165 47.383 1.00 19.66  ? 367 PHE F CD1 1 
ATOM   15987 C CD2 . PHE F 1 165 ? -1.565  -24.262 46.286 1.00 19.04  ? 367 PHE F CD2 1 
ATOM   15988 C CE1 . PHE F 1 165 ? -2.795  -22.077 47.407 1.00 20.28  ? 367 PHE F CE1 1 
ATOM   15989 C CE2 . PHE F 1 165 ? -2.936  -24.182 46.303 1.00 19.75  ? 367 PHE F CE2 1 
ATOM   15990 C CZ  . PHE F 1 165 ? -3.553  -23.089 46.865 1.00 20.42  ? 367 PHE F CZ  1 
ATOM   15991 N N   . PRO F 1 166 ? 0.307   -23.539 50.188 1.00 24.78  ? 368 PRO F N   1 
ATOM   15992 C CA  . PRO F 1 166 ? 0.237   -24.433 51.355 1.00 25.07  ? 368 PRO F CA  1 
ATOM   15993 C C   . PRO F 1 166 ? -0.287  -25.824 51.058 1.00 25.89  ? 368 PRO F C   1 
ATOM   15994 O O   . PRO F 1 166 ? 0.087   -26.763 51.768 1.00 27.08  ? 368 PRO F O   1 
ATOM   15995 C CB  . PRO F 1 166 ? -0.703  -23.686 52.308 1.00 21.93  ? 368 PRO F CB  1 
ATOM   15996 C CG  . PRO F 1 166 ? -0.592  -22.265 51.901 1.00 22.31  ? 368 PRO F CG  1 
ATOM   15997 C CD  . PRO F 1 166 ? -0.447  -22.297 50.412 1.00 22.62  ? 368 PRO F CD  1 
ATOM   15998 N N   . ALA F 1 167 ? -1.148  -25.997 50.063 1.00 26.36  ? 369 ALA F N   1 
ATOM   15999 C CA  . ALA F 1 167 ? -1.735  -27.304 49.809 1.00 26.54  ? 369 ALA F CA  1 
ATOM   16000 C C   . ALA F 1 167 ? -0.773  -28.276 49.145 1.00 27.57  ? 369 ALA F C   1 
ATOM   16001 O O   . ALA F 1 167 ? -1.083  -29.468 49.061 1.00 28.06  ? 369 ALA F O   1 
ATOM   16002 C CB  . ALA F 1 167 ? -2.988  -27.167 48.945 1.00 28.07  ? 369 ALA F CB  1 
ATOM   16003 N N   . ASP F 1 168 ? 0.380   -27.809 48.682 1.00 29.57  ? 370 ASP F N   1 
ATOM   16004 C CA  . ASP F 1 168 ? 1.315   -28.680 47.993 1.00 31.78  ? 370 ASP F CA  1 
ATOM   16005 C C   . ASP F 1 168 ? 2.012   -29.609 48.978 1.00 29.77  ? 370 ASP F C   1 
ATOM   16006 O O   . ASP F 1 168 ? 2.308   -29.240 50.117 1.00 30.06  ? 370 ASP F O   1 
ATOM   16007 C CB  . ASP F 1 168 ? 2.353   -27.859 47.232 1.00 26.81  ? 370 ASP F CB  1 
ATOM   16008 C CG  . ASP F 1 168 ? 1.753   -27.097 46.070 1.00 33.04  ? 370 ASP F CG  1 
ATOM   16009 O OD1 . ASP F 1 168 ? 0.608   -27.409 45.684 1.00 35.60  ? 370 ASP F OD1 1 
ATOM   16010 O OD2 . ASP F 1 168 ? 2.428   -26.191 45.539 1.00 35.99  ? 370 ASP F OD2 1 
ATOM   16011 N N   . VAL F 1 169 ? 2.269   -30.832 48.526 1.00 37.58  ? 371 VAL F N   1 
ATOM   16012 C CA  . VAL F 1 169 ? 3.019   -31.820 49.290 1.00 34.52  ? 371 VAL F CA  1 
ATOM   16013 C C   . VAL F 1 169 ? 4.384   -31.966 48.636 1.00 34.06  ? 371 VAL F C   1 
ATOM   16014 O O   . VAL F 1 169 ? 4.473   -32.249 47.436 1.00 33.94  ? 371 VAL F O   1 
ATOM   16015 C CB  . VAL F 1 169 ? 2.277   -33.165 49.350 1.00 34.22  ? 371 VAL F CB  1 
ATOM   16016 C CG1 . VAL F 1 169 ? 3.096   -34.188 50.102 1.00 32.92  ? 371 VAL F CG1 1 
ATOM   16017 C CG2 . VAL F 1 169 ? 0.917   -32.990 49.995 1.00 33.28  ? 371 VAL F CG2 1 
ATOM   16018 N N   . PHE F 1 170 ? 5.445   -31.776 49.417 1.00 32.79  ? 372 PHE F N   1 
ATOM   16019 C CA  . PHE F 1 170 ? 6.780   -31.663 48.856 1.00 32.92  ? 372 PHE F CA  1 
ATOM   16020 C C   . PHE F 1 170 ? 7.691   -32.740 49.427 1.00 33.56  ? 372 PHE F C   1 
ATOM   16021 O O   . PHE F 1 170 ? 7.394   -33.369 50.445 1.00 33.46  ? 372 PHE F O   1 
ATOM   16022 C CB  . PHE F 1 170 ? 7.387   -30.278 49.124 1.00 30.28  ? 372 PHE F CB  1 
ATOM   16023 C CG  . PHE F 1 170 ? 7.784   -30.047 50.555 1.00 30.46  ? 372 PHE F CG  1 
ATOM   16024 C CD1 . PHE F 1 170 ? 9.095   -30.226 50.954 1.00 29.99  ? 372 PHE F CD1 1 
ATOM   16025 C CD2 . PHE F 1 170 ? 6.849   -29.686 51.505 1.00 30.73  ? 372 PHE F CD2 1 
ATOM   16026 C CE1 . PHE F 1 170 ? 9.469   -30.020 52.260 1.00 29.87  ? 372 PHE F CE1 1 
ATOM   16027 C CE2 . PHE F 1 170 ? 7.221   -29.479 52.813 1.00 30.17  ? 372 PHE F CE2 1 
ATOM   16028 C CZ  . PHE F 1 170 ? 8.531   -29.649 53.191 1.00 29.50  ? 372 PHE F CZ  1 
ATOM   16029 N N   . MET F 1 171 ? 8.810   -32.936 48.742 1.00 33.14  ? 373 MET F N   1 
ATOM   16030 C CA  . MET F 1 171 ? 9.807   -33.938 49.079 1.00 33.00  ? 373 MET F CA  1 
ATOM   16031 C C   . MET F 1 171 ? 11.015  -33.266 49.720 1.00 31.31  ? 373 MET F C   1 
ATOM   16032 O O   . MET F 1 171 ? 11.394  -32.156 49.338 1.00 32.52  ? 373 MET F O   1 
ATOM   16033 C CB  . MET F 1 171 ? 10.213  -34.690 47.812 1.00 32.33  ? 373 MET F CB  1 
ATOM   16034 C CG  . MET F 1 171 ? 11.253  -35.766 47.968 1.00 37.03  ? 373 MET F CG  1 
ATOM   16035 S SD  . MET F 1 171 ? 11.436  -36.607 46.387 1.00 42.08  ? 373 MET F SD  1 
ATOM   16036 C CE  . MET F 1 171 ? 12.854  -37.635 46.715 1.00 43.99  ? 373 MET F CE  1 
ATOM   16037 N N   . ILE F 1 172 ? 11.609  -33.932 50.700 1.00 37.03  ? 374 ILE F N   1 
ATOM   16038 C CA  . ILE F 1 172 ? 12.769  -33.371 51.398 1.00 35.70  ? 374 ILE F CA  1 
ATOM   16039 C C   . ILE F 1 172 ? 14.019  -33.616 50.557 1.00 35.03  ? 374 ILE F C   1 
ATOM   16040 O O   . ILE F 1 172 ? 14.238  -34.751 50.106 1.00 35.61  ? 374 ILE F O   1 
ATOM   16041 C CB  . ILE F 1 172 ? 12.912  -33.987 52.784 1.00 35.21  ? 374 ILE F CB  1 
ATOM   16042 C CG1 . ILE F 1 172 ? 11.740  -33.584 53.670 1.00 36.29  ? 374 ILE F CG1 1 
ATOM   16043 C CG2 . ILE F 1 172 ? 14.201  -33.538 53.437 1.00 34.43  ? 374 ILE F CG2 1 
ATOM   16044 C CD1 . ILE F 1 172 ? 11.725  -34.308 54.985 1.00 40.44  ? 374 ILE F CD1 1 
ATOM   16045 N N   . PRO F 1 173 ? 14.847  -32.604 50.324 1.00 34.10  ? 375 PRO F N   1 
ATOM   16046 C CA  . PRO F 1 173 ? 16.035  -32.793 49.489 1.00 34.23  ? 375 PRO F CA  1 
ATOM   16047 C C   . PRO F 1 173 ? 17.149  -33.514 50.231 1.00 34.55  ? 375 PRO F C   1 
ATOM   16048 O O   . PRO F 1 173 ? 17.280  -33.436 51.453 1.00 35.26  ? 375 PRO F O   1 
ATOM   16049 C CB  . PRO F 1 173 ? 16.448  -31.360 49.143 1.00 33.40  ? 375 PRO F CB  1 
ATOM   16050 C CG  . PRO F 1 173 ? 15.971  -30.563 50.299 1.00 33.00  ? 375 PRO F CG  1 
ATOM   16051 C CD  . PRO F 1 173 ? 14.691  -31.204 50.750 1.00 33.38  ? 375 PRO F CD  1 
ATOM   16052 N N   . GLN F 1 174 ? 17.969  -34.216 49.454 1.00 35.61  ? 376 GLN F N   1 
ATOM   16053 C CA  . GLN F 1 174 ? 19.084  -34.973 50.005 1.00 34.91  ? 376 GLN F CA  1 
ATOM   16054 C C   . GLN F 1 174 ? 20.208  -34.033 50.421 1.00 35.16  ? 376 GLN F C   1 
ATOM   16055 O O   . GLN F 1 174 ? 20.476  -33.031 49.756 1.00 35.44  ? 376 GLN F O   1 
ATOM   16056 C CB  . GLN F 1 174 ? 19.596  -35.979 48.975 1.00 35.40  ? 376 GLN F CB  1 
ATOM   16057 C CG  . GLN F 1 174 ? 20.637  -36.942 49.502 1.00 35.88  ? 376 GLN F CG  1 
ATOM   16058 C CD  . GLN F 1 174 ? 21.044  -37.970 48.471 1.00 38.26  ? 376 GLN F CD  1 
ATOM   16059 O OE1 . GLN F 1 174 ? 20.501  -38.007 47.370 1.00 39.63  ? 376 GLN F OE1 1 
ATOM   16060 N NE2 . GLN F 1 174 ? 22.000  -38.815 48.823 1.00 38.90  ? 376 GLN F NE2 1 
ATOM   16061 N N   . TYR F 1 175 ? 20.867  -34.359 51.529 1.00 34.48  ? 377 TYR F N   1 
ATOM   16062 C CA  . TYR F 1 175 ? 21.950  -33.533 52.038 1.00 33.72  ? 377 TYR F CA  1 
ATOM   16063 C C   . TYR F 1 175 ? 23.300  -34.094 51.619 1.00 34.55  ? 377 TYR F C   1 
ATOM   16064 O O   . TYR F 1 175 ? 23.537  -35.303 51.683 1.00 34.94  ? 377 TYR F O   1 
ATOM   16065 C CB  . TYR F 1 175 ? 21.885  -33.424 53.561 1.00 35.06  ? 377 TYR F CB  1 
ATOM   16066 C CG  . TYR F 1 175 ? 23.041  -32.659 54.167 1.00 35.32  ? 377 TYR F CG  1 
ATOM   16067 C CD1 . TYR F 1 175 ? 23.107  -31.278 54.073 1.00 35.00  ? 377 TYR F CD1 1 
ATOM   16068 C CD2 . TYR F 1 175 ? 24.055  -33.316 54.846 1.00 35.29  ? 377 TYR F CD2 1 
ATOM   16069 C CE1 . TYR F 1 175 ? 24.156  -30.577 54.624 1.00 35.02  ? 377 TYR F CE1 1 
ATOM   16070 C CE2 . TYR F 1 175 ? 25.106  -32.621 55.403 1.00 35.25  ? 377 TYR F CE2 1 
ATOM   16071 C CZ  . TYR F 1 175 ? 25.151  -31.253 55.289 1.00 36.10  ? 377 TYR F CZ  1 
ATOM   16072 O OH  . TYR F 1 175 ? 26.196  -30.556 55.841 1.00 35.99  ? 377 TYR F OH  1 
ATOM   16073 N N   . GLY F 1 176 ? 24.181  -33.198 51.189 1.00 36.24  ? 378 GLY F N   1 
ATOM   16074 C CA  . GLY F 1 176 ? 25.525  -33.551 50.776 1.00 36.41  ? 378 GLY F CA  1 
ATOM   16075 C C   . GLY F 1 176 ? 26.383  -32.310 50.793 1.00 36.59  ? 378 GLY F C   1 
ATOM   16076 O O   . GLY F 1 176 ? 25.885  -31.184 50.759 1.00 36.34  ? 378 GLY F O   1 
ATOM   16077 N N   . TYR F 1 177 ? 27.692  -32.527 50.847 1.00 36.93  ? 379 TYR F N   1 
ATOM   16078 C CA  . TYR F 1 177 ? 28.616  -31.414 50.977 1.00 37.31  ? 379 TYR F CA  1 
ATOM   16079 C C   . TYR F 1 177 ? 29.865  -31.686 50.158 1.00 38.01  ? 379 TYR F C   1 
ATOM   16080 O O   . TYR F 1 177 ? 30.127  -32.815 49.740 1.00 37.86  ? 379 TYR F O   1 
ATOM   16081 C CB  . TYR F 1 177 ? 28.970  -31.162 52.443 1.00 40.69  ? 379 TYR F CB  1 
ATOM   16082 C CG  . TYR F 1 177 ? 29.647  -32.322 53.131 1.00 41.41  ? 379 TYR F CG  1 
ATOM   16083 C CD1 . TYR F 1 177 ? 31.029  -32.435 53.145 1.00 41.28  ? 379 TYR F CD1 1 
ATOM   16084 C CD2 . TYR F 1 177 ? 28.904  -33.300 53.772 1.00 41.45  ? 379 TYR F CD2 1 
ATOM   16085 C CE1 . TYR F 1 177 ? 31.649  -33.490 53.775 1.00 42.16  ? 379 TYR F CE1 1 
ATOM   16086 C CE2 . TYR F 1 177 ? 29.515  -34.359 54.404 1.00 42.23  ? 379 TYR F CE2 1 
ATOM   16087 C CZ  . TYR F 1 177 ? 30.888  -34.449 54.402 1.00 43.24  ? 379 TYR F CZ  1 
ATOM   16088 O OH  . TYR F 1 177 ? 31.504  -35.505 55.031 1.00 44.39  ? 379 TYR F OH  1 
ATOM   16089 N N   . LEU F 1 178 ? 30.632  -30.625 49.935 1.00 39.15  ? 380 LEU F N   1 
ATOM   16090 C CA  . LEU F 1 178 ? 31.866  -30.678 49.170 1.00 40.17  ? 380 LEU F CA  1 
ATOM   16091 C C   . LEU F 1 178 ? 33.038  -30.249 50.040 1.00 42.51  ? 380 LEU F C   1 
ATOM   16092 O O   . LEU F 1 178 ? 32.869  -29.555 51.044 1.00 43.71  ? 380 LEU F O   1 
ATOM   16093 C CB  . LEU F 1 178 ? 31.781  -29.786 47.930 1.00 37.58  ? 380 LEU F CB  1 
ATOM   16094 C CG  . LEU F 1 178 ? 30.785  -30.258 46.877 1.00 37.96  ? 380 LEU F CG  1 
ATOM   16095 C CD1 . LEU F 1 178 ? 30.643  -29.231 45.780 1.00 37.56  ? 380 LEU F CD1 1 
ATOM   16096 C CD2 . LEU F 1 178 ? 31.249  -31.579 46.307 1.00 37.41  ? 380 LEU F CD2 1 
ATOM   16097 N N   . THR F 1 179 ? 34.233  -30.670 49.640 1.00 42.63  ? 381 THR F N   1 
ATOM   16098 C CA  . THR F 1 179 ? 35.446  -30.368 50.387 1.00 45.16  ? 381 THR F CA  1 
ATOM   16099 C C   . THR F 1 179 ? 36.581  -30.042 49.426 1.00 45.38  ? 381 THR F C   1 
ATOM   16100 O O   . THR F 1 179 ? 36.349  -29.856 48.227 1.00 45.28  ? 381 THR F O   1 
ATOM   16101 C CB  . THR F 1 179 ? 35.820  -31.536 51.304 1.00 46.67  ? 381 THR F CB  1 
ATOM   16102 O OG1 . THR F 1 179 ? 36.931  -31.168 52.130 1.00 48.38  ? 381 THR F OG1 1 
ATOM   16103 C CG2 . THR F 1 179 ? 36.178  -32.766 50.493 1.00 48.58  ? 381 THR F CG2 1 
ATOM   16104 N N   . LEU F 1 180 ? 37.801  -29.939 49.945 1.00 46.88  ? 382 LEU F N   1 
ATOM   16105 C CA  . LEU F 1 180 ? 38.948  -29.630 49.103 1.00 47.38  ? 382 LEU F CA  1 
ATOM   16106 C C   . LEU F 1 180 ? 39.192  -30.740 48.088 1.00 48.97  ? 382 LEU F C   1 
ATOM   16107 O O   . LEU F 1 180 ? 38.853  -31.905 48.309 1.00 49.29  ? 382 LEU F O   1 
ATOM   16108 C CB  . LEU F 1 180 ? 40.196  -29.429 49.955 1.00 43.93  ? 382 LEU F CB  1 
ATOM   16109 C CG  . LEU F 1 180 ? 40.168  -28.249 50.919 1.00 43.39  ? 382 LEU F CG  1 
ATOM   16110 C CD1 . LEU F 1 180 ? 41.434  -28.227 51.755 1.00 43.05  ? 382 LEU F CD1 1 
ATOM   16111 C CD2 . LEU F 1 180 ? 39.992  -26.952 50.155 1.00 42.71  ? 382 LEU F CD2 1 
ATOM   16112 N N   . ASN F 1 181 ? 39.795  -30.365 46.963 1.00 49.82  ? 383 ASN F N   1 
ATOM   16113 C CA  . ASN F 1 181 ? 40.095  -31.312 45.904 1.00 51.89  ? 383 ASN F CA  1 
ATOM   16114 C C   . ASN F 1 181 ? 41.257  -30.802 45.066 1.00 54.54  ? 383 ASN F C   1 
ATOM   16115 O O   . ASN F 1 181 ? 41.566  -29.608 45.048 1.00 54.62  ? 383 ASN F O   1 
ATOM   16116 C CB  . ASN F 1 181 ? 38.887  -31.547 44.991 1.00 49.75  ? 383 ASN F CB  1 
ATOM   16117 C CG  . ASN F 1 181 ? 38.453  -30.289 44.266 1.00 50.08  ? 383 ASN F CG  1 
ATOM   16118 O OD1 . ASN F 1 181 ? 38.780  -29.177 44.675 1.00 51.07  ? 383 ASN F OD1 1 
ATOM   16119 N ND2 . ASN F 1 181 ? 37.746  -30.460 43.162 1.00 49.82  ? 383 ASN F ND2 1 
ATOM   16120 N N   . ASP F 1 182 ? 41.902  -31.735 44.372 1.00 55.42  ? 384 ASP F N   1 
ATOM   16121 C CA  . ASP F 1 182 ? 42.794  -31.431 43.259 1.00 58.03  ? 384 ASP F CA  1 
ATOM   16122 C C   . ASP F 1 182 ? 42.351  -32.302 42.093 1.00 57.13  ? 384 ASP F C   1 
ATOM   16123 O O   . ASP F 1 182 ? 42.526  -33.524 42.128 1.00 57.32  ? 384 ASP F O   1 
ATOM   16124 C CB  . ASP F 1 182 ? 44.254  -31.694 43.620 1.00 58.30  ? 384 ASP F CB  1 
ATOM   16125 C CG  . ASP F 1 182 ? 45.197  -31.399 42.474 1.00 62.62  ? 384 ASP F CG  1 
ATOM   16126 O OD1 . ASP F 1 182 ? 45.332  -30.214 42.107 1.00 65.53  ? 384 ASP F OD1 1 
ATOM   16127 O OD2 . ASP F 1 182 ? 45.797  -32.351 41.935 1.00 64.93  ? 384 ASP F OD2 1 
ATOM   16128 N N   . GLY F 1 183 ? 41.805  -31.679 41.056 1.00 56.07  ? 385 GLY F N   1 
ATOM   16129 C CA  . GLY F 1 183 ? 41.138  -32.464 40.032 1.00 55.13  ? 385 GLY F CA  1 
ATOM   16130 C C   . GLY F 1 183 ? 39.985  -33.224 40.657 1.00 54.73  ? 385 GLY F C   1 
ATOM   16131 O O   . GLY F 1 183 ? 39.257  -32.700 41.506 1.00 55.01  ? 385 GLY F O   1 
ATOM   16132 N N   . SER F 1 184 ? 39.816  -34.478 40.249 1.00 50.70  ? 386 SER F N   1 
ATOM   16133 C CA  . SER F 1 184 ? 38.817  -35.346 40.854 1.00 49.27  ? 386 SER F CA  1 
ATOM   16134 C C   . SER F 1 184 ? 39.264  -35.919 42.188 1.00 48.69  ? 386 SER F C   1 
ATOM   16135 O O   . SER F 1 184 ? 38.413  -36.253 43.018 1.00 48.86  ? 386 SER F O   1 
ATOM   16136 C CB  . SER F 1 184 ? 38.470  -36.499 39.911 1.00 54.43  ? 386 SER F CB  1 
ATOM   16137 O OG  . SER F 1 184 ? 39.592  -37.332 39.689 1.00 56.12  ? 386 SER F OG  1 
ATOM   16138 N N   . GLN F 1 185 ? 40.567  -36.035 42.411 1.00 49.52  ? 387 GLN F N   1 
ATOM   16139 C CA  . GLN F 1 185 ? 41.088  -36.643 43.621 1.00 48.96  ? 387 GLN F CA  1 
ATOM   16140 C C   . GLN F 1 185 ? 40.900  -35.720 44.816 1.00 48.65  ? 387 GLN F C   1 
ATOM   16141 O O   . GLN F 1 185 ? 40.714  -34.509 44.682 1.00 48.76  ? 387 GLN F O   1 
ATOM   16142 C CB  . GLN F 1 185 ? 42.570  -36.975 43.460 1.00 47.74  ? 387 GLN F CB  1 
ATOM   16143 C CG  . GLN F 1 185 ? 42.865  -38.042 42.432 1.00 49.16  ? 387 GLN F CG  1 
ATOM   16144 C CD  . GLN F 1 185 ? 44.350  -38.289 42.277 1.00 50.92  ? 387 GLN F CD  1 
ATOM   16145 O OE1 . GLN F 1 185 ? 45.167  -37.416 42.565 1.00 52.30  ? 387 GLN F OE1 1 
ATOM   16146 N NE2 . GLN F 1 185 ? 44.709  -39.483 41.824 1.00 50.61  ? 387 GLN F NE2 1 
ATOM   16147 N N   . ALA F 1 186 ? 40.949  -36.315 46.000 1.00 49.83  ? 388 ALA F N   1 
ATOM   16148 C CA  . ALA F 1 186 ? 40.941  -35.579 47.250 1.00 48.92  ? 388 ALA F CA  1 
ATOM   16149 C C   . ALA F 1 186 ? 42.358  -35.142 47.602 1.00 48.87  ? 388 ALA F C   1 
ATOM   16150 O O   . ALA F 1 186 ? 43.320  -35.402 46.877 1.00 48.67  ? 388 ALA F O   1 
ATOM   16151 C CB  . ALA F 1 186 ? 40.349  -36.431 48.370 1.00 44.66  ? 388 ALA F CB  1 
ATOM   16152 N N   . VAL F 1 187 ? 42.483  -34.466 48.741 1.00 46.60  ? 389 VAL F N   1 
ATOM   16153 C CA  . VAL F 1 187 ? 43.773  -34.088 49.296 1.00 47.37  ? 389 VAL F CA  1 
ATOM   16154 C C   . VAL F 1 187 ? 43.771  -34.442 50.775 1.00 46.97  ? 389 VAL F C   1 
ATOM   16155 O O   . VAL F 1 187 ? 42.737  -34.770 51.359 1.00 46.94  ? 389 VAL F O   1 
ATOM   16156 C CB  . VAL F 1 187 ? 44.091  -32.593 49.098 1.00 45.79  ? 389 VAL F CB  1 
ATOM   16157 C CG1 . VAL F 1 187 ? 44.229  -32.275 47.621 1.00 48.65  ? 389 VAL F CG1 1 
ATOM   16158 C CG2 . VAL F 1 187 ? 43.014  -31.739 49.733 1.00 45.51  ? 389 VAL F CG2 1 
ATOM   16159 N N   . GLY F 1 188 ? 44.959  -34.385 51.376 1.00 46.96  ? 390 GLY F N   1 
ATOM   16160 C CA  . GLY F 1 188 ? 45.097  -34.734 52.778 1.00 46.22  ? 390 GLY F CA  1 
ATOM   16161 C C   . GLY F 1 188 ? 44.271  -33.877 53.711 1.00 46.20  ? 390 GLY F C   1 
ATOM   16162 O O   . GLY F 1 188 ? 43.871  -34.347 54.781 1.00 46.23  ? 390 GLY F O   1 
ATOM   16163 N N   . ARG F 1 189 ? 43.996  -32.632 53.328 1.00 45.94  ? 391 ARG F N   1 
ATOM   16164 C CA  . ARG F 1 189 ? 43.264  -31.715 54.190 1.00 44.95  ? 391 ARG F CA  1 
ATOM   16165 C C   . ARG F 1 189 ? 41.751  -31.841 54.031 1.00 43.45  ? 391 ARG F C   1 
ATOM   16166 O O   . ARG F 1 189 ? 41.007  -31.242 54.815 1.00 44.13  ? 391 ARG F O   1 
ATOM   16167 C CB  . ARG F 1 189 ? 43.733  -30.281 53.916 1.00 41.41  ? 391 ARG F CB  1 
ATOM   16168 C CG  . ARG F 1 189 ? 43.151  -29.236 54.847 1.00 45.19  ? 391 ARG F CG  1 
ATOM   16169 C CD  . ARG F 1 189 ? 43.823  -27.883 54.718 1.00 48.47  ? 391 ARG F CD  1 
ATOM   16170 N NE  . ARG F 1 189 ? 45.194  -27.875 55.221 1.00 52.51  ? 391 ARG F NE  1 
ATOM   16171 C CZ  . ARG F 1 189 ? 46.272  -27.768 54.455 1.00 54.61  ? 391 ARG F CZ  1 
ATOM   16172 N NH1 . ARG F 1 189 ? 46.145  -27.642 53.143 1.00 55.15  ? 391 ARG F NH1 1 
ATOM   16173 N NH2 . ARG F 1 189 ? 47.478  -27.767 55.003 1.00 56.22  ? 391 ARG F NH2 1 
ATOM   16174 N N   . SER F 1 190 ? 41.277  -32.622 53.065 1.00 48.59  ? 392 SER F N   1 
ATOM   16175 C CA  . SER F 1 190 ? 39.848  -32.869 52.935 1.00 47.36  ? 392 SER F CA  1 
ATOM   16176 C C   . SER F 1 190 ? 39.293  -33.505 54.204 1.00 47.36  ? 392 SER F C   1 
ATOM   16177 O O   . SER F 1 190 ? 39.921  -34.368 54.820 1.00 46.81  ? 392 SER F O   1 
ATOM   16178 C CB  . SER F 1 190 ? 39.569  -33.773 51.737 1.00 47.67  ? 392 SER F CB  1 
ATOM   16179 O OG  . SER F 1 190 ? 39.937  -33.144 50.524 1.00 48.68  ? 392 SER F OG  1 
ATOM   16180 N N   . SER F 1 191 ? 38.098  -33.071 54.591 1.00 50.44  ? 393 SER F N   1 
ATOM   16181 C CA  . SER F 1 191 ? 37.467  -33.502 55.829 1.00 48.93  ? 393 SER F CA  1 
ATOM   16182 C C   . SER F 1 191 ? 36.271  -34.395 55.533 1.00 48.30  ? 393 SER F C   1 
ATOM   16183 O O   . SER F 1 191 ? 35.597  -34.232 54.511 1.00 48.72  ? 393 SER F O   1 
ATOM   16184 C CB  . SER F 1 191 ? 37.020  -32.302 56.664 1.00 44.81  ? 393 SER F CB  1 
ATOM   16185 O OG  . SER F 1 191 ? 38.132  -31.542 57.103 1.00 48.70  ? 393 SER F OG  1 
ATOM   16186 N N   . PHE F 1 192 ? 36.017  -35.338 56.435 1.00 46.12  ? 394 PHE F N   1 
ATOM   16187 C CA  . PHE F 1 192 ? 34.880  -36.241 56.350 1.00 45.07  ? 394 PHE F CA  1 
ATOM   16188 C C   . PHE F 1 192 ? 34.011  -36.067 57.585 1.00 46.33  ? 394 PHE F C   1 
ATOM   16189 O O   . PHE F 1 192 ? 34.509  -36.103 58.713 1.00 46.36  ? 394 PHE F O   1 
ATOM   16190 C CB  . PHE F 1 192 ? 35.346  -37.692 56.224 1.00 44.09  ? 394 PHE F CB  1 
ATOM   16191 C CG  . PHE F 1 192 ? 34.232  -38.693 56.249 1.00 43.54  ? 394 PHE F CG  1 
ATOM   16192 C CD1 . PHE F 1 192 ? 33.460  -38.917 55.126 1.00 43.46  ? 394 PHE F CD1 1 
ATOM   16193 C CD2 . PHE F 1 192 ? 33.971  -39.427 57.392 1.00 43.88  ? 394 PHE F CD2 1 
ATOM   16194 C CE1 . PHE F 1 192 ? 32.438  -39.842 55.147 1.00 43.01  ? 394 PHE F CE1 1 
ATOM   16195 C CE2 . PHE F 1 192 ? 32.952  -40.353 57.416 1.00 43.29  ? 394 PHE F CE2 1 
ATOM   16196 C CZ  . PHE F 1 192 ? 32.185  -40.561 56.293 1.00 42.76  ? 394 PHE F CZ  1 
ATOM   16197 N N   . TYR F 1 193 ? 32.714  -35.867 57.371 1.00 45.22  ? 395 TYR F N   1 
ATOM   16198 C CA  . TYR F 1 193 ? 31.769  -35.634 58.454 1.00 45.96  ? 395 TYR F CA  1 
ATOM   16199 C C   . TYR F 1 193 ? 30.673  -36.688 58.423 1.00 47.61  ? 395 TYR F C   1 
ATOM   16200 O O   . TYR F 1 193 ? 30.011  -36.874 57.397 1.00 47.71  ? 395 TYR F O   1 
ATOM   16201 C CB  . TYR F 1 193 ? 31.153  -34.235 58.368 1.00 42.97  ? 395 TYR F CB  1 
ATOM   16202 C CG  . TYR F 1 193 ? 32.138  -33.115 58.609 1.00 44.17  ? 395 TYR F CG  1 
ATOM   16203 C CD1 . TYR F 1 193 ? 32.426  -32.685 59.896 1.00 45.18  ? 395 TYR F CD1 1 
ATOM   16204 C CD2 . TYR F 1 193 ? 32.768  -32.479 57.551 1.00 45.33  ? 395 TYR F CD2 1 
ATOM   16205 C CE1 . TYR F 1 193 ? 33.320  -31.665 60.122 1.00 47.01  ? 395 TYR F CE1 1 
ATOM   16206 C CE2 . TYR F 1 193 ? 33.664  -31.456 57.769 1.00 47.74  ? 395 TYR F CE2 1 
ATOM   16207 C CZ  . TYR F 1 193 ? 33.937  -31.054 59.056 1.00 48.17  ? 395 TYR F CZ  1 
ATOM   16208 O OH  . TYR F 1 193 ? 34.829  -30.033 59.278 1.00 49.76  ? 395 TYR F OH  1 
ATOM   16209 N N   . CYS F 1 194 ? 30.487  -37.369 59.548 1.00 46.52  ? 396 CYS F N   1 
ATOM   16210 C CA  . CYS F 1 194 ? 29.427  -38.354 59.712 1.00 47.72  ? 396 CYS F CA  1 
ATOM   16211 C C   . CYS F 1 194 ? 28.308  -37.731 60.536 1.00 47.10  ? 396 CYS F C   1 
ATOM   16212 O O   . CYS F 1 194 ? 28.535  -37.300 61.672 1.00 47.74  ? 396 CYS F O   1 
ATOM   16213 C CB  . CYS F 1 194 ? 29.959  -39.618 60.388 1.00 45.48  ? 396 CYS F CB  1 
ATOM   16214 S SG  . CYS F 1 194 ? 28.736  -40.922 60.608 1.00 53.68  ? 396 CYS F SG  1 
ATOM   16215 N N   . LEU F 1 195 ? 27.105  -37.678 59.964 1.00 41.95  ? 397 LEU F N   1 
ATOM   16216 C CA  . LEU F 1 195 ? 25.976  -37.084 60.667 1.00 42.27  ? 397 LEU F CA  1 
ATOM   16217 C C   . LEU F 1 195 ? 25.441  -37.985 61.770 1.00 43.84  ? 397 LEU F C   1 
ATOM   16218 O O   . LEU F 1 195 ? 24.591  -37.548 62.551 1.00 44.17  ? 397 LEU F O   1 
ATOM   16219 C CB  . LEU F 1 195 ? 24.855  -36.739 59.685 1.00 40.51  ? 397 LEU F CB  1 
ATOM   16220 C CG  . LEU F 1 195 ? 24.959  -35.381 58.984 1.00 38.62  ? 397 LEU F CG  1 
ATOM   16221 C CD1 . LEU F 1 195 ? 26.154  -35.320 58.052 1.00 36.55  ? 397 LEU F CD1 1 
ATOM   16222 C CD2 . LEU F 1 195 ? 23.684  -35.074 58.226 1.00 38.28  ? 397 LEU F CD2 1 
ATOM   16223 N N   . GLU F 1 196 ? 25.919  -39.227 61.848 1.00 46.79  ? 398 GLU F N   1 
ATOM   16224 C CA  . GLU F 1 196 ? 25.602  -40.094 62.973 1.00 48.25  ? 398 GLU F CA  1 
ATOM   16225 C C   . GLU F 1 196 ? 26.422  -39.756 64.207 1.00 47.87  ? 398 GLU F C   1 
ATOM   16226 O O   . GLU F 1 196 ? 26.068  -40.191 65.308 1.00 48.34  ? 398 GLU F O   1 
ATOM   16227 C CB  . GLU F 1 196 ? 25.841  -41.551 62.585 1.00 40.97  ? 398 GLU F CB  1 
ATOM   16228 C CG  . GLU F 1 196 ? 24.968  -42.042 61.455 1.00 47.96  ? 398 GLU F CG  1 
ATOM   16229 C CD  . GLU F 1 196 ? 23.497  -41.962 61.785 1.00 52.35  ? 398 GLU F CD  1 
ATOM   16230 O OE1 . GLU F 1 196 ? 23.132  -42.246 62.945 1.00 55.99  ? 398 GLU F OE1 1 
ATOM   16231 O OE2 . GLU F 1 196 ? 22.705  -41.617 60.884 1.00 53.26  ? 398 GLU F OE2 1 
ATOM   16232 N N   . TYR F 1 197 ? 27.498  -38.991 64.051 1.00 50.88  ? 399 TYR F N   1 
ATOM   16233 C CA  . TYR F 1 197 ? 28.407  -38.662 65.136 1.00 50.63  ? 399 TYR F CA  1 
ATOM   16234 C C   . TYR F 1 197 ? 27.905  -37.491 65.976 1.00 49.30  ? 399 TYR F C   1 
ATOM   16235 O O   . TYR F 1 197 ? 28.563  -37.107 66.947 1.00 48.89  ? 399 TYR F O   1 
ATOM   16236 C CB  . TYR F 1 197 ? 29.800  -38.378 64.557 1.00 54.30  ? 399 TYR F CB  1 
ATOM   16237 C CG  . TYR F 1 197 ? 30.877  -38.047 65.564 1.00 57.68  ? 399 TYR F CG  1 
ATOM   16238 C CD1 . TYR F 1 197 ? 31.431  -39.035 66.366 1.00 58.42  ? 399 TYR F CD1 1 
ATOM   16239 C CD2 . TYR F 1 197 ? 31.370  -36.757 65.683 1.00 58.77  ? 399 TYR F CD2 1 
ATOM   16240 C CE1 . TYR F 1 197 ? 32.422  -38.741 67.280 1.00 60.25  ? 399 TYR F CE1 1 
ATOM   16241 C CE2 . TYR F 1 197 ? 32.362  -36.455 66.592 1.00 60.92  ? 399 TYR F CE2 1 
ATOM   16242 C CZ  . TYR F 1 197 ? 32.885  -37.450 67.388 1.00 62.14  ? 399 TYR F CZ  1 
ATOM   16243 O OH  . TYR F 1 197 ? 33.874  -37.150 68.294 1.00 65.48  ? 399 TYR F OH  1 
ATOM   16244 N N   . PHE F 1 198 ? 26.749  -36.923 65.628 1.00 46.48  ? 400 PHE F N   1 
ATOM   16245 C CA  . PHE F 1 198 ? 26.027  -35.868 66.322 1.00 45.57  ? 400 PHE F CA  1 
ATOM   16246 C C   . PHE F 1 198 ? 24.866  -36.443 67.123 1.00 45.35  ? 400 PHE F C   1 
ATOM   16247 O O   . PHE F 1 198 ? 24.066  -37.219 66.594 1.00 46.88  ? 400 PHE F O   1 
ATOM   16248 C CB  . PHE F 1 198 ? 25.491  -34.847 65.329 1.00 44.33  ? 400 PHE F CB  1 
ATOM   16249 C CG  . PHE F 1 198 ? 26.558  -34.097 64.602 1.00 43.80  ? 400 PHE F CG  1 
ATOM   16250 C CD1 . PHE F 1 198 ? 27.099  -32.945 65.140 1.00 43.52  ? 400 PHE F CD1 1 
ATOM   16251 C CD2 . PHE F 1 198 ? 27.033  -34.552 63.390 1.00 43.50  ? 400 PHE F CD2 1 
ATOM   16252 C CE1 . PHE F 1 198 ? 28.085  -32.255 64.474 1.00 44.57  ? 400 PHE F CE1 1 
ATOM   16253 C CE2 . PHE F 1 198 ? 28.021  -33.870 62.723 1.00 44.35  ? 400 PHE F CE2 1 
ATOM   16254 C CZ  . PHE F 1 198 ? 28.548  -32.717 63.264 1.00 45.31  ? 400 PHE F CZ  1 
ATOM   16255 N N   . PRO F 1 199 ? 24.748  -36.084 68.399 1.00 45.40  ? 401 PRO F N   1 
ATOM   16256 C CA  . PRO F 1 199 ? 23.590  -36.536 69.177 1.00 44.92  ? 401 PRO F CA  1 
ATOM   16257 C C   . PRO F 1 199 ? 22.292  -36.002 68.590 1.00 44.24  ? 401 PRO F C   1 
ATOM   16258 O O   . PRO F 1 199 ? 22.148  -34.804 68.338 1.00 44.01  ? 401 PRO F O   1 
ATOM   16259 C CB  . PRO F 1 199 ? 23.857  -35.964 70.573 1.00 42.10  ? 401 PRO F CB  1 
ATOM   16260 C CG  . PRO F 1 199 ? 24.738  -34.790 70.329 1.00 42.30  ? 401 PRO F CG  1 
ATOM   16261 C CD  . PRO F 1 199 ? 25.613  -35.179 69.173 1.00 43.62  ? 401 PRO F CD  1 
ATOM   16262 N N   . SER F 1 200 ? 21.342  -36.909 68.380 1.00 44.19  ? 402 SER F N   1 
ATOM   16263 C CA  . SER F 1 200 ? 20.096  -36.587 67.704 1.00 43.50  ? 402 SER F CA  1 
ATOM   16264 C C   . SER F 1 200 ? 18.927  -37.151 68.495 1.00 42.47  ? 402 SER F C   1 
ATOM   16265 O O   . SER F 1 200 ? 19.097  -37.963 69.406 1.00 42.71  ? 402 SER F O   1 
ATOM   16266 C CB  . SER F 1 200 ? 20.072  -37.131 66.269 1.00 41.36  ? 402 SER F CB  1 
ATOM   16267 O OG  . SER F 1 200 ? 20.114  -38.545 66.254 1.00 42.97  ? 402 SER F OG  1 
ATOM   16268 N N   . GLN F 1 201 ? 17.729  -36.706 68.131 1.00 42.46  ? 403 GLN F N   1 
ATOM   16269 C CA  . GLN F 1 201 ? 16.504  -37.152 68.775 1.00 42.23  ? 403 GLN F CA  1 
ATOM   16270 C C   . GLN F 1 201 ? 15.718  -38.054 67.835 1.00 42.06  ? 403 GLN F C   1 
ATOM   16271 O O   . GLN F 1 201 ? 15.577  -37.758 66.645 1.00 42.50  ? 403 GLN F O   1 
ATOM   16272 C CB  . GLN F 1 201 ? 15.653  -35.953 69.190 1.00 42.80  ? 403 GLN F CB  1 
ATOM   16273 C CG  . GLN F 1 201 ? 14.390  -36.310 69.946 1.00 48.56  ? 403 GLN F CG  1 
ATOM   16274 C CD  . GLN F 1 201 ? 13.652  -35.085 70.445 1.00 50.99  ? 403 GLN F CD  1 
ATOM   16275 O OE1 . GLN F 1 201 ? 14.151  -33.964 70.345 1.00 52.16  ? 403 GLN F OE1 1 
ATOM   16276 N NE2 . GLN F 1 201 ? 12.450  -35.288 70.971 1.00 51.95  ? 403 GLN F NE2 1 
ATOM   16277 N N   . MET F 1 202 ? 15.214  -39.160 68.373 1.00 45.65  ? 404 MET F N   1 
ATOM   16278 C CA  . MET F 1 202 ? 14.456  -40.135 67.602 1.00 45.28  ? 404 MET F CA  1 
ATOM   16279 C C   . MET F 1 202 ? 12.988  -40.040 67.992 1.00 45.06  ? 404 MET F C   1 
ATOM   16280 O O   . MET F 1 202 ? 12.662  -39.943 69.179 1.00 46.48  ? 404 MET F O   1 
ATOM   16281 C CB  . MET F 1 202 ? 14.998  -41.548 67.832 1.00 42.34  ? 404 MET F CB  1 
ATOM   16282 C CG  . MET F 1 202 ? 16.438  -41.711 67.366 1.00 44.58  ? 404 MET F CG  1 
ATOM   16283 S SD  . MET F 1 202 ? 17.182  -43.321 67.688 1.00 48.24  ? 404 MET F SD  1 
ATOM   16284 C CE  . MET F 1 202 ? 16.395  -44.323 66.440 1.00 46.77  ? 404 MET F CE  1 
ATOM   16285 N N   . LEU F 1 203 ? 12.108  -40.060 66.993 1.00 47.00  ? 405 LEU F N   1 
ATOM   16286 C CA  . LEU F 1 203 ? 10.686  -39.804 67.182 1.00 46.90  ? 405 LEU F CA  1 
ATOM   16287 C C   . LEU F 1 203 ? 9.882   -40.946 66.581 1.00 47.19  ? 405 LEU F C   1 
ATOM   16288 O O   . LEU F 1 203 ? 10.137  -41.352 65.443 1.00 47.46  ? 405 LEU F O   1 
ATOM   16289 C CB  . LEU F 1 203 ? 10.276  -38.485 66.521 1.00 46.26  ? 405 LEU F CB  1 
ATOM   16290 C CG  . LEU F 1 203 ? 10.503  -37.138 67.205 1.00 44.18  ? 405 LEU F CG  1 
ATOM   16291 C CD1 . LEU F 1 203 ? 11.977  -36.822 67.335 1.00 42.22  ? 405 LEU F CD1 1 
ATOM   16292 C CD2 . LEU F 1 203 ? 9.801   -36.055 66.413 1.00 43.53  ? 405 LEU F CD2 1 
ATOM   16293 N N   . ARG F 1 204 ? 8.911   -41.459 67.335 1.00 46.48  ? 406 ARG F N   1 
ATOM   16294 C CA  . ARG F 1 204 ? 7.899   -42.333 66.765 1.00 48.26  ? 406 ARG F CA  1 
ATOM   16295 C C   . ARG F 1 204 ? 6.678   -41.514 66.352 1.00 49.75  ? 406 ARG F C   1 
ATOM   16296 O O   . ARG F 1 204 ? 6.694   -40.282 66.349 1.00 49.71  ? 406 ARG F O   1 
ATOM   16297 C CB  . ARG F 1 204 ? 7.507   -43.444 67.737 1.00 49.12  ? 406 ARG F CB  1 
ATOM   16298 C CG  . ARG F 1 204 ? 8.573   -44.497 67.936 1.00 48.95  ? 406 ARG F CG  1 
ATOM   16299 C CD  . ARG F 1 204 ? 8.069   -45.642 68.799 1.00 48.69  ? 406 ARG F CD  1 
ATOM   16300 N NE  . ARG F 1 204 ? 9.089   -46.666 68.995 1.00 52.80  ? 406 ARG F NE  1 
ATOM   16301 C CZ  . ARG F 1 204 ? 8.935   -47.741 69.761 1.00 53.45  ? 406 ARG F CZ  1 
ATOM   16302 N NH1 . ARG F 1 204 ? 7.795   -47.940 70.407 1.00 54.19  ? 406 ARG F NH1 1 
ATOM   16303 N NH2 . ARG F 1 204 ? 9.920   -48.619 69.878 1.00 53.62  ? 406 ARG F NH2 1 
ATOM   16304 N N   . THR F 1 205 ? 5.595   -42.211 66.001 1.00 46.70  ? 407 THR F N   1 
ATOM   16305 C CA  . THR F 1 205 ? 4.422   -41.540 65.457 1.00 48.25  ? 407 THR F CA  1 
ATOM   16306 C C   . THR F 1 205 ? 3.673   -40.713 66.494 1.00 49.31  ? 407 THR F C   1 
ATOM   16307 O O   . THR F 1 205 ? 2.791   -39.934 66.119 1.00 54.58  ? 407 THR F O   1 
ATOM   16308 C CB  . THR F 1 205 ? 3.472   -42.560 64.830 1.00 48.87  ? 407 THR F CB  1 
ATOM   16309 O OG1 . THR F 1 205 ? 2.430   -41.870 64.129 1.00 52.19  ? 407 THR F OG1 1 
ATOM   16310 C CG2 . THR F 1 205 ? 2.855   -43.446 65.901 1.00 47.74  ? 407 THR F CG2 1 
ATOM   16311 N N   . GLY F 1 206 ? 3.984   -40.867 67.780 1.00 50.58  ? 408 GLY F N   1 
ATOM   16312 C CA  . GLY F 1 206 ? 3.388   -40.019 68.793 1.00 50.51  ? 408 GLY F CA  1 
ATOM   16313 C C   . GLY F 1 206 ? 4.267   -38.905 69.311 1.00 49.09  ? 408 GLY F C   1 
ATOM   16314 O O   . GLY F 1 206 ? 3.771   -37.990 69.972 1.00 49.97  ? 408 GLY F O   1 
ATOM   16315 N N   . ASN F 1 207 ? 5.565   -38.967 69.035 1.00 47.30  ? 409 ASN F N   1 
ATOM   16316 C CA  . ASN F 1 207 ? 6.513   -37.956 69.469 1.00 46.20  ? 409 ASN F CA  1 
ATOM   16317 C C   . ASN F 1 207 ? 6.511   -36.761 68.519 1.00 45.70  ? 409 ASN F C   1 
ATOM   16318 O O   . ASN F 1 207 ? 6.166   -36.870 67.340 1.00 45.95  ? 409 ASN F O   1 
ATOM   16319 C CB  . ASN F 1 207 ? 7.915   -38.555 69.558 1.00 50.82  ? 409 ASN F CB  1 
ATOM   16320 C CG  . ASN F 1 207 ? 7.992   -39.709 70.535 1.00 50.95  ? 409 ASN F CG  1 
ATOM   16321 O OD1 . ASN F 1 207 ? 8.516   -40.773 70.212 1.00 52.07  ? 409 ASN F OD1 1 
ATOM   16322 N ND2 . ASN F 1 207 ? 7.465   -39.507 71.735 1.00 51.73  ? 409 ASN F ND2 1 
ATOM   16323 N N   . ASN F 1 208 ? 6.909   -35.606 69.048 1.00 43.81  ? 410 ASN F N   1 
ATOM   16324 C CA  . ASN F 1 208 ? 7.070   -34.396 68.253 1.00 43.48  ? 410 ASN F CA  1 
ATOM   16325 C C   . ASN F 1 208 ? 8.383   -33.709 68.615 1.00 43.58  ? 410 ASN F C   1 
ATOM   16326 O O   . ASN F 1 208 ? 8.996   -33.989 69.648 1.00 43.82  ? 410 ASN F O   1 
ATOM   16327 C CB  . ASN F 1 208 ? 5.871   -33.448 68.424 1.00 44.33  ? 410 ASN F CB  1 
ATOM   16328 C CG  . ASN F 1 208 ? 5.636   -33.038 69.867 1.00 45.30  ? 410 ASN F CG  1 
ATOM   16329 O OD1 . ASN F 1 208 ? 6.568   -32.899 70.655 1.00 48.32  ? 410 ASN F OD1 1 
ATOM   16330 N ND2 . ASN F 1 208 ? 4.373   -32.837 70.216 1.00 45.80  ? 410 ASN F ND2 1 
ATOM   16331 N N   . PHE F 1 209 ? 8.813   -32.797 67.743 1.00 41.17  ? 411 PHE F N   1 
ATOM   16332 C CA  . PHE F 1 209 ? 10.099  -32.123 67.867 1.00 42.03  ? 411 PHE F CA  1 
ATOM   16333 C C   . PHE F 1 209 ? 9.918   -30.627 67.675 1.00 42.47  ? 411 PHE F C   1 
ATOM   16334 O O   . PHE F 1 209 ? 9.162   -30.196 66.801 1.00 43.00  ? 411 PHE F O   1 
ATOM   16335 C CB  . PHE F 1 209 ? 11.102  -32.658 66.837 1.00 39.51  ? 411 PHE F CB  1 
ATOM   16336 C CG  . PHE F 1 209 ? 12.403  -31.912 66.808 1.00 40.21  ? 411 PHE F CG  1 
ATOM   16337 C CD1 . PHE F 1 209 ? 13.376  -32.152 67.758 1.00 40.73  ? 411 PHE F CD1 1 
ATOM   16338 C CD2 . PHE F 1 209 ? 12.659  -30.979 65.818 1.00 39.89  ? 411 PHE F CD2 1 
ATOM   16339 C CE1 . PHE F 1 209 ? 14.573  -31.469 67.727 1.00 39.92  ? 411 PHE F CE1 1 
ATOM   16340 C CE2 . PHE F 1 209 ? 13.855  -30.296 65.783 1.00 40.45  ? 411 PHE F CE2 1 
ATOM   16341 C CZ  . PHE F 1 209 ? 14.812  -30.541 66.739 1.00 39.83  ? 411 PHE F CZ  1 
ATOM   16342 N N   . GLN F 1 210 ? 10.615  -29.837 68.491 1.00 38.65  ? 412 GLN F N   1 
ATOM   16343 C CA  . GLN F 1 210 ? 10.570  -28.391 68.345 1.00 41.24  ? 412 GLN F CA  1 
ATOM   16344 C C   . GLN F 1 210 ? 11.850  -27.772 68.886 1.00 40.36  ? 412 GLN F C   1 
ATOM   16345 O O   . GLN F 1 210 ? 12.523  -28.339 69.748 1.00 41.28  ? 412 GLN F O   1 
ATOM   16346 C CB  . GLN F 1 210 ? 9.359   -27.784 69.061 1.00 40.35  ? 412 GLN F CB  1 
ATOM   16347 C CG  . GLN F 1 210 ? 9.395   -27.930 70.567 1.00 48.91  ? 412 GLN F CG  1 
ATOM   16348 C CD  . GLN F 1 210 ? 8.198   -27.294 71.235 1.00 56.55  ? 412 GLN F CD  1 
ATOM   16349 O OE1 . GLN F 1 210 ? 7.172   -27.059 70.599 1.00 59.41  ? 412 GLN F OE1 1 
ATOM   16350 N NE2 . GLN F 1 210 ? 8.323   -27.006 72.524 1.00 57.95  ? 412 GLN F NE2 1 
ATOM   16351 N N   . PHE F 1 211 ? 12.176  -26.594 68.358 1.00 38.93  ? 413 PHE F N   1 
ATOM   16352 C CA  . PHE F 1 211 ? 13.237  -25.764 68.911 1.00 38.05  ? 413 PHE F CA  1 
ATOM   16353 C C   . PHE F 1 211 ? 12.965  -24.327 68.495 1.00 37.70  ? 413 PHE F C   1 
ATOM   16354 O O   . PHE F 1 211 ? 12.191  -24.068 67.570 1.00 36.85  ? 413 PHE F O   1 
ATOM   16355 C CB  . PHE F 1 211 ? 14.627  -26.208 68.441 1.00 35.35  ? 413 PHE F CB  1 
ATOM   16356 C CG  . PHE F 1 211 ? 14.906  -25.916 66.997 1.00 35.93  ? 413 PHE F CG  1 
ATOM   16357 C CD1 . PHE F 1 211 ? 15.555  -24.749 66.632 1.00 36.76  ? 413 PHE F CD1 1 
ATOM   16358 C CD2 . PHE F 1 211 ? 14.515  -26.792 66.007 1.00 36.80  ? 413 PHE F CD2 1 
ATOM   16359 C CE1 . PHE F 1 211 ? 15.812  -24.465 65.309 1.00 36.63  ? 413 PHE F CE1 1 
ATOM   16360 C CE2 . PHE F 1 211 ? 14.767  -26.509 64.680 1.00 37.67  ? 413 PHE F CE2 1 
ATOM   16361 C CZ  . PHE F 1 211 ? 15.419  -25.346 64.332 1.00 37.62  ? 413 PHE F CZ  1 
ATOM   16362 N N   . SER F 1 212 ? 13.614  -23.395 69.186 1.00 33.63  ? 414 SER F N   1 
ATOM   16363 C CA  . SER F 1 212 ? 13.443  -21.976 68.918 1.00 33.33  ? 414 SER F CA  1 
ATOM   16364 C C   . SER F 1 212 ? 14.802  -21.321 68.714 1.00 32.95  ? 414 SER F C   1 
ATOM   16365 O O   . SER F 1 212 ? 15.757  -21.579 69.449 1.00 33.06  ? 414 SER F O   1 
ATOM   16366 C CB  . SER F 1 212 ? 12.680  -21.278 70.051 1.00 32.95  ? 414 SER F CB  1 
ATOM   16367 O OG  . SER F 1 212 ? 13.398  -21.348 71.269 1.00 37.77  ? 414 SER F OG  1 
ATOM   16368 N N   . TYR F 1 213 ? 14.873  -20.457 67.705 1.00 29.85  ? 415 TYR F N   1 
ATOM   16369 C CA  . TYR F 1 213 ? 16.108  -19.782 67.334 1.00 30.15  ? 415 TYR F CA  1 
ATOM   16370 C C   . TYR F 1 213 ? 15.933  -18.275 67.455 1.00 32.06  ? 415 TYR F C   1 
ATOM   16371 O O   . TYR F 1 213 ? 14.821  -17.752 67.350 1.00 31.98  ? 415 TYR F O   1 
ATOM   16372 C CB  . TYR F 1 213 ? 16.543  -20.161 65.910 1.00 29.63  ? 415 TYR F CB  1 
ATOM   16373 C CG  . TYR F 1 213 ? 17.663  -19.313 65.365 1.00 29.96  ? 415 TYR F CG  1 
ATOM   16374 C CD1 . TYR F 1 213 ? 18.969  -19.484 65.800 1.00 28.31  ? 415 TYR F CD1 1 
ATOM   16375 C CD2 . TYR F 1 213 ? 17.412  -18.334 64.413 1.00 30.90  ? 415 TYR F CD2 1 
ATOM   16376 C CE1 . TYR F 1 213 ? 19.990  -18.701 65.305 1.00 30.09  ? 415 TYR F CE1 1 
ATOM   16377 C CE2 . TYR F 1 213 ? 18.425  -17.552 63.910 1.00 30.84  ? 415 TYR F CE2 1 
ATOM   16378 C CZ  . TYR F 1 213 ? 19.711  -17.738 64.359 1.00 31.29  ? 415 TYR F CZ  1 
ATOM   16379 O OH  . TYR F 1 213 ? 20.722  -16.955 63.858 1.00 33.71  ? 415 TYR F OH  1 
ATOM   16380 N N   . GLU F 1 214 ? 17.049  -17.584 67.674 1.00 30.79  ? 416 GLU F N   1 
ATOM   16381 C CA  . GLU F 1 214 ? 17.089  -16.135 67.825 1.00 33.41  ? 416 GLU F CA  1 
ATOM   16382 C C   . GLU F 1 214 ? 18.030  -15.553 66.778 1.00 32.14  ? 416 GLU F C   1 
ATOM   16383 O O   . GLU F 1 214 ? 19.224  -15.864 66.776 1.00 32.80  ? 416 GLU F O   1 
ATOM   16384 C CB  . GLU F 1 214 ? 17.559  -15.756 69.228 1.00 27.26  ? 416 GLU F CB  1 
ATOM   16385 C CG  . GLU F 1 214 ? 17.587  -14.267 69.511 1.00 38.86  ? 416 GLU F CG  1 
ATOM   16386 C CD  . GLU F 1 214 ? 16.206  -13.662 69.615 1.00 45.19  ? 416 GLU F CD  1 
ATOM   16387 O OE1 . GLU F 1 214 ? 15.229  -14.425 69.758 1.00 47.01  ? 416 GLU F OE1 1 
ATOM   16388 O OE2 . GLU F 1 214 ? 16.097  -12.421 69.555 1.00 49.34  ? 416 GLU F OE2 1 
ATOM   16389 N N   . PHE F 1 215 ? 17.496  -14.709 65.897 1.00 33.79  ? 417 PHE F N   1 
ATOM   16390 C CA  . PHE F 1 215 ? 18.334  -14.033 64.914 1.00 33.72  ? 417 PHE F CA  1 
ATOM   16391 C C   . PHE F 1 215 ? 19.280  -13.046 65.584 1.00 36.48  ? 417 PHE F C   1 
ATOM   16392 O O   . PHE F 1 215 ? 18.891  -12.293 66.480 1.00 36.05  ? 417 PHE F O   1 
ATOM   16393 C CB  . PHE F 1 215 ? 17.472  -13.299 63.885 1.00 33.19  ? 417 PHE F CB  1 
ATOM   16394 C CG  . PHE F 1 215 ? 16.779  -14.203 62.914 1.00 30.19  ? 417 PHE F CG  1 
ATOM   16395 C CD1 . PHE F 1 215 ? 17.402  -14.579 61.740 1.00 28.63  ? 417 PHE F CD1 1 
ATOM   16396 C CD2 . PHE F 1 215 ? 15.516  -14.693 63.178 1.00 29.39  ? 417 PHE F CD2 1 
ATOM   16397 C CE1 . PHE F 1 215 ? 16.774  -15.409 60.841 1.00 27.55  ? 417 PHE F CE1 1 
ATOM   16398 C CE2 . PHE F 1 215 ? 14.885  -15.531 62.283 1.00 27.85  ? 417 PHE F CE2 1 
ATOM   16399 C CZ  . PHE F 1 215 ? 15.517  -15.888 61.113 1.00 27.66  ? 417 PHE F CZ  1 
ATOM   16400 N N   . GLU F 1 216 ? 20.533  -13.055 65.143 1.00 32.80  ? 418 GLU F N   1 
ATOM   16401 C CA  . GLU F 1 216 ? 21.467  -12.029 65.566 1.00 36.88  ? 418 GLU F CA  1 
ATOM   16402 C C   . GLU F 1 216 ? 21.152  -10.719 64.856 1.00 36.93  ? 418 GLU F C   1 
ATOM   16403 O O   . GLU F 1 216 ? 20.459  -10.686 63.836 1.00 36.52  ? 418 GLU F O   1 
ATOM   16404 C CB  . GLU F 1 216 ? 22.910  -12.448 65.290 1.00 32.68  ? 418 GLU F CB  1 
ATOM   16405 C CG  . GLU F 1 216 ? 23.246  -12.625 63.828 1.00 39.93  ? 418 GLU F CG  1 
ATOM   16406 C CD  . GLU F 1 216 ? 24.655  -13.139 63.625 1.00 44.98  ? 418 GLU F CD  1 
ATOM   16407 O OE1 . GLU F 1 216 ? 25.463  -13.041 64.571 1.00 48.35  ? 418 GLU F OE1 1 
ATOM   16408 O OE2 . GLU F 1 216 ? 24.957  -13.643 62.525 1.00 46.74  ? 418 GLU F OE2 1 
ATOM   16409 N N   . ASN F 1 217 ? 21.656  -9.627  65.424 1.00 34.66  ? 419 ASN F N   1 
ATOM   16410 C CA  . ASN F 1 217 ? 21.348  -8.303  64.906 1.00 35.83  ? 419 ASN F CA  1 
ATOM   16411 C C   . ASN F 1 217 ? 21.793  -8.166  63.455 1.00 34.60  ? 419 ASN F C   1 
ATOM   16412 O O   . ASN F 1 217 ? 22.957  -8.402  63.123 1.00 35.15  ? 419 ASN F O   1 
ATOM   16413 C CB  . ASN F 1 217 ? 22.025  -7.240  65.766 1.00 32.09  ? 419 ASN F CB  1 
ATOM   16414 C CG  . ASN F 1 217 ? 21.531  -5.847  65.460 1.00 37.49  ? 419 ASN F CG  1 
ATOM   16415 O OD1 . ASN F 1 217 ? 20.377  -5.657  65.079 1.00 40.47  ? 419 ASN F OD1 1 
ATOM   16416 N ND2 . ASN F 1 217 ? 22.405  -4.860  65.619 1.00 39.83  ? 419 ASN F ND2 1 
ATOM   16417 N N   . VAL F 1 218 ? 20.857  -7.783  62.593 1.00 32.87  ? 420 VAL F N   1 
ATOM   16418 C CA  . VAL F 1 218 ? 21.159  -7.497  61.193 1.00 31.34  ? 420 VAL F CA  1 
ATOM   16419 C C   . VAL F 1 218 ? 20.532  -6.156  60.841 1.00 29.98  ? 420 VAL F C   1 
ATOM   16420 O O   . VAL F 1 218 ? 19.545  -5.732  61.462 1.00 29.98  ? 420 VAL F O   1 
ATOM   16421 C CB  . VAL F 1 218 ? 20.643  -8.612  60.252 1.00 30.00  ? 420 VAL F CB  1 
ATOM   16422 C CG1 . VAL F 1 218 ? 21.351  -9.920  60.537 1.00 32.97  ? 420 VAL F CG1 1 
ATOM   16423 C CG2 . VAL F 1 218 ? 19.142  -8.773  60.384 1.00 31.14  ? 420 VAL F CG2 1 
ATOM   16424 N N   . PRO F 1 219 ? 21.091  -5.453  59.862 1.00 27.00  ? 421 PRO F N   1 
ATOM   16425 C CA  . PRO F 1 219 ? 20.467  -4.206  59.418 1.00 25.72  ? 421 PRO F CA  1 
ATOM   16426 C C   . PRO F 1 219 ? 19.182  -4.478  58.658 1.00 24.98  ? 421 PRO F C   1 
ATOM   16427 O O   . PRO F 1 219 ? 19.028  -5.510  58.003 1.00 25.59  ? 421 PRO F O   1 
ATOM   16428 C CB  . PRO F 1 219 ? 21.531  -3.583  58.510 1.00 25.08  ? 421 PRO F CB  1 
ATOM   16429 C CG  . PRO F 1 219 ? 22.300  -4.750  58.002 1.00 25.65  ? 421 PRO F CG  1 
ATOM   16430 C CD  . PRO F 1 219 ? 22.344  -5.728  59.138 1.00 25.36  ? 421 PRO F CD  1 
ATOM   16431 N N   . PHE F 1 220 ? 18.247  -3.538  58.770 1.00 21.76  ? 422 PHE F N   1 
ATOM   16432 C CA  . PHE F 1 220 ? 17.031  -3.592  57.972 1.00 19.78  ? 422 PHE F CA  1 
ATOM   16433 C C   . PHE F 1 220 ? 17.383  -3.658  56.496 1.00 19.45  ? 422 PHE F C   1 
ATOM   16434 O O   . PHE F 1 220 ? 18.165  -2.841  56.001 1.00 19.39  ? 422 PHE F O   1 
ATOM   16435 C CB  . PHE F 1 220 ? 16.164  -2.360  58.219 1.00 20.87  ? 422 PHE F CB  1 
ATOM   16436 C CG  . PHE F 1 220 ? 15.582  -2.279  59.592 1.00 22.52  ? 422 PHE F CG  1 
ATOM   16437 C CD1 . PHE F 1 220 ? 14.390  -2.908  59.886 1.00 22.48  ? 422 PHE F CD1 1 
ATOM   16438 C CD2 . PHE F 1 220 ? 16.214  -1.557  60.583 1.00 22.55  ? 422 PHE F CD2 1 
ATOM   16439 C CE1 . PHE F 1 220 ? 13.844  -2.827  61.146 1.00 22.32  ? 422 PHE F CE1 1 
ATOM   16440 C CE2 . PHE F 1 220 ? 15.674  -1.473  61.845 1.00 21.71  ? 422 PHE F CE2 1 
ATOM   16441 C CZ  . PHE F 1 220 ? 14.488  -2.109  62.127 1.00 21.97  ? 422 PHE F CZ  1 
ATOM   16442 N N   . HIS F 1 221 ? 16.704  -4.525  55.758 1.00 16.93  ? 423 HIS F N   1 
ATOM   16443 C CA  . HIS F 1 221 ? 16.880  -4.534  54.320 1.00 17.07  ? 423 HIS F CA  1 
ATOM   16444 C C   . HIS F 1 221 ? 16.119  -3.292  53.888 1.00 17.76  ? 423 HIS F C   1 
ATOM   16445 O O   . HIS F 1 221 ? 15.018  -3.057  54.365 1.00 17.94  ? 423 HIS F O   1 
ATOM   16446 C CB  . HIS F 1 221 ? 16.246  -5.757  53.686 1.00 13.86  ? 423 HIS F CB  1 
ATOM   16447 C CG  . HIS F 1 221 ? 16.112  -5.652  52.201 1.00 15.52  ? 423 HIS F CG  1 
ATOM   16448 N ND1 . HIS F 1 221 ? 17.007  -6.232  51.332 1.00 16.62  ? 423 HIS F ND1 1 
ATOM   16449 C CD2 . HIS F 1 221 ? 15.197  -5.021  51.432 1.00 15.85  ? 423 HIS F CD2 1 
ATOM   16450 C CE1 . HIS F 1 221 ? 16.647  -5.967  50.091 1.00 17.24  ? 423 HIS F CE1 1 
ATOM   16451 N NE2 . HIS F 1 221 ? 15.552  -5.233  50.124 1.00 17.09  ? 423 HIS F NE2 1 
ATOM   16452 N N   . SER F 1 222 ? 16.665  -2.498  52.979 1.00 15.17  ? 424 SER F N   1 
ATOM   16453 C CA  . SER F 1 222 ? 15.970  -1.275  52.594 1.00 15.49  ? 424 SER F CA  1 
ATOM   16454 C C   . SER F 1 222 ? 15.017  -1.472  51.433 1.00 14.92  ? 424 SER F C   1 
ATOM   16455 O O   . SER F 1 222 ? 15.434  -1.557  50.288 1.00 15.59  ? 424 SER F O   1 
ATOM   16456 C CB  . SER F 1 222 ? 16.984  -0.205  52.215 1.00 18.48  ? 424 SER F CB  1 
ATOM   16457 O OG  . SER F 1 222 ? 17.514  -0.455  50.933 1.00 22.07  ? 424 SER F OG  1 
ATOM   16458 N N   . SER F 1 223 ? 13.727  -1.531  51.733 1.00 15.55  ? 425 SER F N   1 
ATOM   16459 C CA  . SER F 1 223 ? 12.727  -1.704  50.699 1.00 15.20  ? 425 SER F CA  1 
ATOM   16460 C C   . SER F 1 223 ? 12.246  -0.375  50.153 1.00 14.37  ? 425 SER F C   1 
ATOM   16461 O O   . SER F 1 223 ? 11.084  -0.022  50.309 1.00 15.08  ? 425 SER F O   1 
ATOM   16462 C CB  . SER F 1 223 ? 11.548  -2.504  51.237 1.00 13.72  ? 425 SER F CB  1 
ATOM   16463 O OG  . SER F 1 223 ? 11.101  -1.973  52.459 1.00 15.87  ? 425 SER F OG  1 
ATOM   16464 N N   . TYR F 1 224 ? 13.142  0.360   49.510 1.00 13.30  ? 426 TYR F N   1 
ATOM   16465 C CA  . TYR F 1 224 ? 12.792  1.644   48.932 1.00 13.74  ? 426 TYR F CA  1 
ATOM   16466 C C   . TYR F 1 224 ? 13.767  2.035   47.842 1.00 13.67  ? 426 TYR F C   1 
ATOM   16467 O O   . TYR F 1 224 ? 14.862  1.500   47.751 1.00 14.04  ? 426 TYR F O   1 
ATOM   16468 C CB  . TYR F 1 224 ? 12.754  2.726   50.006 1.00 11.94  ? 426 TYR F CB  1 
ATOM   16469 C CG  . TYR F 1 224 ? 14.090  2.995   50.631 1.00 13.32  ? 426 TYR F CG  1 
ATOM   16470 C CD1 . TYR F 1 224 ? 15.092  3.618   49.917 1.00 13.78  ? 426 TYR F CD1 1 
ATOM   16471 C CD2 . TYR F 1 224 ? 14.349  2.627   51.936 1.00 14.12  ? 426 TYR F CD2 1 
ATOM   16472 C CE1 . TYR F 1 224 ? 16.318  3.861   50.485 1.00 16.10  ? 426 TYR F CE1 1 
ATOM   16473 C CE2 . TYR F 1 224 ? 15.571  2.869   52.512 1.00 16.12  ? 426 TYR F CE2 1 
ATOM   16474 C CZ  . TYR F 1 224 ? 16.551  3.486   51.778 1.00 16.99  ? 426 TYR F CZ  1 
ATOM   16475 O OH  . TYR F 1 224 ? 17.771  3.728   52.349 1.00 18.30  ? 426 TYR F OH  1 
ATOM   16476 N N   . ALA F 1 225 ? 13.358  2.984   47.018 1.00 12.51  ? 427 ALA F N   1 
ATOM   16477 C CA  . ALA F 1 225 ? 14.185  3.496   45.944 1.00 12.48  ? 427 ALA F CA  1 
ATOM   16478 C C   . ALA F 1 225 ? 14.409  4.968   46.238 1.00 13.17  ? 427 ALA F C   1 
ATOM   16479 O O   . ALA F 1 225 ? 13.507  5.627   46.730 1.00 13.83  ? 427 ALA F O   1 
ATOM   16480 C CB  . ALA F 1 225 ? 13.478  3.322   44.616 1.00 11.97  ? 427 ALA F CB  1 
ATOM   16481 N N   . HIS F 1 226 ? 15.610  5.480   46.008 1.00 13.44  ? 428 HIS F N   1 
ATOM   16482 C CA  . HIS F 1 226 ? 15.875  6.893   46.255 1.00 13.48  ? 428 HIS F CA  1 
ATOM   16483 C C   . HIS F 1 226 ? 15.173  7.793   45.248 1.00 13.94  ? 428 HIS F C   1 
ATOM   16484 O O   . HIS F 1 226 ? 15.038  7.430   44.090 1.00 12.65  ? 428 HIS F O   1 
ATOM   16485 C CB  . HIS F 1 226 ? 17.369  7.174   46.232 1.00 14.04  ? 428 HIS F CB  1 
ATOM   16486 C CG  . HIS F 1 226 ? 18.139  6.415   47.259 1.00 15.18  ? 428 HIS F CG  1 
ATOM   16487 N ND1 . HIS F 1 226 ? 18.005  6.646   48.609 1.00 14.76  ? 428 HIS F ND1 1 
ATOM   16488 C CD2 . HIS F 1 226 ? 19.059  5.433   47.136 1.00 15.80  ? 428 HIS F CD2 1 
ATOM   16489 C CE1 . HIS F 1 226 ? 18.806  5.837   49.274 1.00 15.18  ? 428 HIS F CE1 1 
ATOM   16490 N NE2 . HIS F 1 226 ? 19.457  5.091   48.403 1.00 16.81  ? 428 HIS F NE2 1 
ATOM   16491 N N   . SER F 1 227 ? 14.743  8.972   45.690 1.00 14.61  ? 429 SER F N   1 
ATOM   16492 C CA  . SER F 1 227 ? 14.063  9.931   44.817 1.00 15.67  ? 429 SER F CA  1 
ATOM   16493 C C   . SER F 1 227 ? 15.008  10.988  44.239 1.00 15.85  ? 429 SER F C   1 
ATOM   16494 O O   . SER F 1 227 ? 14.627  11.758  43.374 1.00 16.39  ? 429 SER F O   1 
ATOM   16495 C CB  . SER F 1 227 ? 12.880  10.585  45.521 1.00 16.10  ? 429 SER F CB  1 
ATOM   16496 O OG  . SER F 1 227 ? 13.285  11.200  46.722 1.00 20.22  ? 429 SER F OG  1 
ATOM   16497 N N   . GLN F 1 228 ? 16.228  11.024  44.753 1.00 15.76  ? 430 GLN F N   1 
ATOM   16498 C CA  . GLN F 1 228 ? 17.292  11.892  44.281 1.00 17.06  ? 430 GLN F CA  1 
ATOM   16499 C C   . GLN F 1 228 ? 18.441  11.034  43.786 1.00 16.66  ? 430 GLN F C   1 
ATOM   16500 O O   . GLN F 1 228 ? 18.548  9.853   44.121 1.00 16.52  ? 430 GLN F O   1 
ATOM   16501 C CB  . GLN F 1 228 ? 17.808  12.831  45.369 1.00 16.10  ? 430 GLN F CB  1 
ATOM   16502 C CG  . GLN F 1 228 ? 16.849  13.903  45.784 1.00 16.85  ? 430 GLN F CG  1 
ATOM   16503 C CD  . GLN F 1 228 ? 17.446  14.808  46.828 1.00 17.39  ? 430 GLN F CD  1 
ATOM   16504 O OE1 . GLN F 1 228 ? 18.305  14.400  47.604 1.00 18.16  ? 430 GLN F OE1 1 
ATOM   16505 N NE2 . GLN F 1 228 ? 17.024  16.060  46.826 1.00 15.41  ? 430 GLN F NE2 1 
ATOM   16506 N N   . SER F 1 229 ? 19.320  11.645  43.003 1.00 16.14  ? 431 SER F N   1 
ATOM   16507 C CA  . SER F 1 229 ? 20.483  10.952  42.480 1.00 15.96  ? 431 SER F CA  1 
ATOM   16508 C C   . SER F 1 229 ? 21.748  11.534  43.093 1.00 15.70  ? 431 SER F C   1 
ATOM   16509 O O   . SER F 1 229 ? 21.775  12.684  43.536 1.00 14.99  ? 431 SER F O   1 
ATOM   16510 C CB  . SER F 1 229 ? 20.550  11.033  40.956 1.00 15.59  ? 431 SER F CB  1 
ATOM   16511 O OG  . SER F 1 229 ? 20.757  12.359  40.525 1.00 20.07  ? 431 SER F OG  1 
ATOM   16512 N N   . LEU F 1 230 ? 22.795  10.710  43.120 1.00 16.43  ? 432 LEU F N   1 
ATOM   16513 C CA  . LEU F 1 230 ? 24.019  11.063  43.827 1.00 15.82  ? 432 LEU F CA  1 
ATOM   16514 C C   . LEU F 1 230 ? 24.631  12.359  43.308 1.00 16.75  ? 432 LEU F C   1 
ATOM   16515 O O   . LEU F 1 230 ? 25.214  13.124  44.084 1.00 17.05  ? 432 LEU F O   1 
ATOM   16516 C CB  . LEU F 1 230 ? 25.019  9.918   43.700 1.00 15.31  ? 432 LEU F CB  1 
ATOM   16517 C CG  . LEU F 1 230 ? 26.242  9.919   44.603 1.00 16.05  ? 432 LEU F CG  1 
ATOM   16518 C CD1 . LEU F 1 230 ? 25.882  10.478  45.962 1.00 15.73  ? 432 LEU F CD1 1 
ATOM   16519 C CD2 . LEU F 1 230 ? 26.729  8.505   44.742 1.00 16.43  ? 432 LEU F CD2 1 
ATOM   16520 N N   . ASP F 1 231 ? 24.519  12.621  42.012 1.00 17.13  ? 433 ASP F N   1 
ATOM   16521 C CA  . ASP F 1 231 ? 25.090  13.814  41.406 1.00 19.20  ? 433 ASP F CA  1 
ATOM   16522 C C   . ASP F 1 231 ? 24.213  15.055  41.547 1.00 18.52  ? 433 ASP F C   1 
ATOM   16523 O O   . ASP F 1 231 ? 24.732  16.172  41.457 1.00 19.59  ? 433 ASP F O   1 
ATOM   16524 C CB  . ASP F 1 231 ? 25.383  13.545  39.929 1.00 17.05  ? 433 ASP F CB  1 
ATOM   16525 C CG  . ASP F 1 231 ? 24.163  13.070  39.171 1.00 21.28  ? 433 ASP F CG  1 
ATOM   16526 O OD1 . ASP F 1 231 ? 23.105  12.874  39.801 1.00 23.33  ? 433 ASP F OD1 1 
ATOM   16527 O OD2 . ASP F 1 231 ? 24.267  12.873  37.944 1.00 24.72  ? 433 ASP F OD2 1 
ATOM   16528 N N   . ARG F 1 232 ? 22.911  14.893  41.769 1.00 18.93  ? 434 ARG F N   1 
ATOM   16529 C CA  . ARG F 1 232 ? 21.957  15.996  41.806 1.00 17.27  ? 434 ARG F CA  1 
ATOM   16530 C C   . ARG F 1 232 ? 21.650  16.504  43.212 1.00 16.99  ? 434 ARG F C   1 
ATOM   16531 O O   . ARG F 1 232 ? 20.666  17.226  43.392 1.00 16.83  ? 434 ARG F O   1 
ATOM   16532 C CB  . ARG F 1 232 ? 20.679  15.607  41.072 1.00 20.49  ? 434 ARG F CB  1 
ATOM   16533 C CG  . ARG F 1 232 ? 20.930  15.408  39.593 1.00 22.53  ? 434 ARG F CG  1 
ATOM   16534 C CD  . ARG F 1 232 ? 21.194  16.744  38.926 1.00 21.14  ? 434 ARG F CD  1 
ATOM   16535 N NE  . ARG F 1 232 ? 21.479  16.626  37.501 1.00 21.06  ? 434 ARG F NE  1 
ATOM   16536 C CZ  . ARG F 1 232 ? 22.703  16.576  36.991 1.00 21.02  ? 434 ARG F CZ  1 
ATOM   16537 N NH1 . ARG F 1 232 ? 23.755  16.646  37.792 1.00 19.90  ? 434 ARG F NH1 1 
ATOM   16538 N NH2 . ARG F 1 232 ? 22.879  16.467  35.684 1.00 23.07  ? 434 ARG F NH2 1 
ATOM   16539 N N   . LEU F 1 233 ? 22.423  16.096  44.218 1.00 17.74  ? 435 LEU F N   1 
ATOM   16540 C CA  . LEU F 1 233 ? 22.201  16.508  45.601 1.00 17.60  ? 435 LEU F CA  1 
ATOM   16541 C C   . LEU F 1 233 ? 22.320  18.014  45.828 1.00 18.40  ? 435 LEU F C   1 
ATOM   16542 O O   . LEU F 1 233 ? 22.001  18.481  46.925 1.00 19.27  ? 435 LEU F O   1 
ATOM   16543 C CB  . LEU F 1 233 ? 23.193  15.788  46.508 1.00 14.93  ? 435 LEU F CB  1 
ATOM   16544 C CG  . LEU F 1 233 ? 23.051  14.272  46.530 1.00 15.46  ? 435 LEU F CG  1 
ATOM   16545 C CD1 . LEU F 1 233 ? 24.154  13.652  47.352 1.00 13.30  ? 435 LEU F CD1 1 
ATOM   16546 C CD2 . LEU F 1 233 ? 21.701  13.894  47.084 1.00 14.93  ? 435 LEU F CD2 1 
ATOM   16547 N N   . MET F 1 234 ? 22.781  18.772  44.841 1.00 20.66  ? 436 MET F N   1 
ATOM   16548 C CA  . MET F 1 234 ? 23.009  20.204  44.958 1.00 21.72  ? 436 MET F CA  1 
ATOM   16549 C C   . MET F 1 234 ? 21.703  20.994  45.030 1.00 21.82  ? 436 MET F C   1 
ATOM   16550 O O   . MET F 1 234 ? 20.627  20.515  44.663 1.00 21.79  ? 436 MET F O   1 
ATOM   16551 C CB  . MET F 1 234 ? 23.808  20.697  43.762 1.00 24.00  ? 436 MET F CB  1 
ATOM   16552 C CG  . MET F 1 234 ? 23.017  20.569  42.486 1.00 26.05  ? 436 MET F CG  1 
ATOM   16553 S SD  . MET F 1 234 ? 24.013  20.839  41.029 1.00 30.68  ? 436 MET F SD  1 
ATOM   16554 C CE  . MET F 1 234 ? 24.706  19.210  40.814 1.00 30.06  ? 436 MET F CE  1 
ATOM   16555 N N   . ASN F 1 235 ? 21.819  22.228  45.511 1.00 22.55  ? 437 ASN F N   1 
ATOM   16556 C CA  . ASN F 1 235 ? 20.733  23.197  45.412 1.00 21.24  ? 437 ASN F CA  1 
ATOM   16557 C C   . ASN F 1 235 ? 20.762  23.842  44.031 1.00 20.56  ? 437 ASN F C   1 
ATOM   16558 O O   . ASN F 1 235 ? 21.739  24.520  43.696 1.00 20.91  ? 437 ASN F O   1 
ATOM   16559 C CB  . ASN F 1 235 ? 20.861  24.261  46.495 1.00 23.10  ? 437 ASN F CB  1 
ATOM   16560 C CG  . ASN F 1 235 ? 19.672  25.211  46.541 1.00 23.63  ? 437 ASN F CG  1 
ATOM   16561 O OD1 . ASN F 1 235 ? 18.925  25.350  45.577 1.00 23.93  ? 437 ASN F OD1 1 
ATOM   16562 N ND2 . ASN F 1 235 ? 19.504  25.880  47.671 1.00 23.33  ? 437 ASN F ND2 1 
ATOM   16563 N N   . PRO F 1 236 ? 19.720  23.675  43.215 1.00 21.23  ? 438 PRO F N   1 
ATOM   16564 C CA  . PRO F 1 236 ? 19.786  24.133  41.820 1.00 20.56  ? 438 PRO F CA  1 
ATOM   16565 C C   . PRO F 1 236 ? 19.853  25.639  41.647 1.00 20.73  ? 438 PRO F C   1 
ATOM   16566 O O   . PRO F 1 236 ? 20.120  26.089  40.529 1.00 21.34  ? 438 PRO F O   1 
ATOM   16567 C CB  . PRO F 1 236 ? 18.498  23.570  41.213 1.00 19.11  ? 438 PRO F CB  1 
ATOM   16568 C CG  . PRO F 1 236 ? 17.572  23.434  42.376 1.00 19.62  ? 438 PRO F CG  1 
ATOM   16569 C CD  . PRO F 1 236 ? 18.434  23.030  43.523 1.00 19.71  ? 438 PRO F CD  1 
ATOM   16570 N N   . LEU F 1 237 ? 19.568  26.432  42.677 1.00 24.07  ? 439 LEU F N   1 
ATOM   16571 C CA  . LEU F 1 237 ? 19.481  27.878  42.514 1.00 23.39  ? 439 LEU F CA  1 
ATOM   16572 C C   . LEU F 1 237 ? 20.765  28.632  42.849 1.00 24.82  ? 439 LEU F C   1 
ATOM   16573 O O   . LEU F 1 237 ? 20.853  29.823  42.538 1.00 25.24  ? 439 LEU F O   1 
ATOM   16574 C CB  . LEU F 1 237 ? 18.349  28.431  43.383 1.00 21.39  ? 439 LEU F CB  1 
ATOM   16575 C CG  . LEU F 1 237 ? 16.957  27.880  43.084 1.00 20.67  ? 439 LEU F CG  1 
ATOM   16576 C CD1 . LEU F 1 237 ? 15.955  28.439  44.069 1.00 18.60  ? 439 LEU F CD1 1 
ATOM   16577 C CD2 . LEU F 1 237 ? 16.550  28.178  41.657 1.00 18.23  ? 439 LEU F CD2 1 
ATOM   16578 N N   . ILE F 1 238 ? 21.696  28.008  43.560 1.00 25.14  ? 440 ILE F N   1 
ATOM   16579 C CA  . ILE F 1 238 ? 22.890  28.714  44.015 1.00 26.19  ? 440 ILE F CA  1 
ATOM   16580 C C   . ILE F 1 238 ? 24.230  28.200  43.500 1.00 28.05  ? 440 ILE F C   1 
ATOM   16581 O O   . ILE F 1 238 ? 24.400  27.017  43.229 1.00 29.36  ? 440 ILE F O   1 
ATOM   16582 C CB  . ILE F 1 238 ? 22.950  28.696  45.561 1.00 25.76  ? 440 ILE F CB  1 
ATOM   16583 C CG1 . ILE F 1 238 ? 21.551  28.600  46.155 1.00 23.70  ? 440 ILE F CG1 1 
ATOM   16584 C CG2 . ILE F 1 238 ? 23.637  29.934  46.110 1.00 25.42  ? 440 ILE F CG2 1 
ATOM   16585 C CD1 . ILE F 1 238 ? 20.750  29.871  46.014 1.00 21.19  ? 440 ILE F CD1 1 
ATOM   16586 N N   . ASP F 1 239 ? 25.177  29.121  43.376 1.00 30.63  ? 441 ASP F N   1 
ATOM   16587 C CA  . ASP F 1 239 ? 26.535  28.840  42.942 1.00 31.74  ? 441 ASP F CA  1 
ATOM   16588 C C   . ASP F 1 239 ? 27.378  28.257  44.059 1.00 30.36  ? 441 ASP F C   1 
ATOM   16589 O O   . ASP F 1 239 ? 26.992  28.268  45.221 1.00 31.33  ? 441 ASP F O   1 
ATOM   16590 C CB  . ASP F 1 239 ? 27.214  30.117  42.469 1.00 33.15  ? 441 ASP F CB  1 
ATOM   16591 C CG  . ASP F 1 239 ? 26.806  30.510  41.086 1.00 39.66  ? 441 ASP F CG  1 
ATOM   16592 O OD1 . ASP F 1 239 ? 25.726  30.079  40.646 1.00 46.28  ? 441 ASP F OD1 1 
ATOM   16593 O OD2 . ASP F 1 239 ? 27.570  31.249  40.437 1.00 41.21  ? 441 ASP F OD2 1 
ATOM   16594 N N   . GLN F 1 240 ? 28.536  27.738  43.681 1.00 36.07  ? 442 GLN F N   1 
ATOM   16595 C CA  . GLN F 1 240 ? 29.490  27.184  44.621 1.00 34.83  ? 442 GLN F CA  1 
ATOM   16596 C C   . GLN F 1 240 ? 30.696  28.111  44.682 1.00 34.71  ? 442 GLN F C   1 
ATOM   16597 O O   . GLN F 1 240 ? 31.142  28.618  43.660 1.00 34.68  ? 442 GLN F O   1 
ATOM   16598 C CB  . GLN F 1 240 ? 29.965  25.815  44.156 1.00 31.92  ? 442 GLN F CB  1 
ATOM   16599 C CG  . GLN F 1 240 ? 29.011  24.678  44.433 1.00 30.16  ? 442 GLN F CG  1 
ATOM   16600 C CD  . GLN F 1 240 ? 29.730  23.354  44.450 1.00 30.29  ? 442 GLN F CD  1 
ATOM   16601 O OE1 . GLN F 1 240 ? 30.589  23.096  43.619 1.00 29.20  ? 442 GLN F OE1 1 
ATOM   16602 N NE2 . GLN F 1 240 ? 29.391  22.512  45.408 1.00 30.41  ? 442 GLN F NE2 1 
ATOM   16603 N N   . TYR F 1 241 ? 31.231  28.338  45.874 1.00 35.15  ? 443 TYR F N   1 
ATOM   16604 C CA  . TYR F 1 241 ? 32.407  29.192  46.018 1.00 33.71  ? 443 TYR F CA  1 
ATOM   16605 C C   . TYR F 1 241 ? 33.675  28.653  45.333 1.00 33.34  ? 443 TYR F C   1 
ATOM   16606 O O   . TYR F 1 241 ? 34.558  29.427  44.979 1.00 34.62  ? 443 TYR F O   1 
ATOM   16607 C CB  . TYR F 1 241 ? 32.665  29.596  47.468 1.00 33.64  ? 443 TYR F CB  1 
ATOM   16608 C CG  . TYR F 1 241 ? 32.494  28.505  48.484 1.00 33.20  ? 443 TYR F CG  1 
ATOM   16609 C CD1 . TYR F 1 241 ? 33.488  27.567  48.700 1.00 32.80  ? 443 TYR F CD1 1 
ATOM   16610 C CD2 . TYR F 1 241 ? 31.352  28.432  49.253 1.00 34.07  ? 443 TYR F CD2 1 
ATOM   16611 C CE1 . TYR F 1 241 ? 33.337  26.575  49.641 1.00 32.96  ? 443 TYR F CE1 1 
ATOM   16612 C CE2 . TYR F 1 241 ? 31.192  27.445  50.197 1.00 34.13  ? 443 TYR F CE2 1 
ATOM   16613 C CZ  . TYR F 1 241 ? 32.188  26.522  50.385 1.00 33.75  ? 443 TYR F CZ  1 
ATOM   16614 O OH  . TYR F 1 241 ? 32.022  25.541  51.322 1.00 33.58  ? 443 TYR F OH  1 
ATOM   16615 N N   . LEU F 1 242 ? 33.793  27.332  45.215 1.00 36.94  ? 444 LEU F N   1 
ATOM   16616 C CA  . LEU F 1 242 ? 34.931  26.693  44.561 1.00 37.09  ? 444 LEU F CA  1 
ATOM   16617 C C   . LEU F 1 242 ? 34.947  26.957  43.057 1.00 37.70  ? 444 LEU F C   1 
ATOM   16618 O O   . LEU F 1 242 ? 33.910  27.194  42.448 1.00 37.99  ? 444 LEU F O   1 
ATOM   16619 C CB  . LEU F 1 242 ? 34.907  25.187  44.804 1.00 32.07  ? 444 LEU F CB  1 
ATOM   16620 C CG  . LEU F 1 242 ? 34.647  24.737  46.235 1.00 31.49  ? 444 LEU F CG  1 
ATOM   16621 C CD1 . LEU F 1 242 ? 34.751  23.226  46.325 1.00 30.76  ? 444 LEU F CD1 1 
ATOM   16622 C CD2 . LEU F 1 242 ? 35.626  25.403  47.182 1.00 30.70  ? 444 LEU F CD2 1 
ATOM   16623 N N   . TYR F 1 243 ? 36.142  26.916  42.477 1.00 38.29  ? 445 TYR F N   1 
ATOM   16624 C CA  . TYR F 1 243 ? 36.332  27.155  41.053 1.00 38.31  ? 445 TYR F CA  1 
ATOM   16625 C C   . TYR F 1 243 ? 36.876  25.931  40.333 1.00 38.34  ? 445 TYR F C   1 
ATOM   16626 O O   . TYR F 1 243 ? 37.432  25.031  40.954 1.00 38.30  ? 445 TYR F O   1 
ATOM   16627 C CB  . TYR F 1 243 ? 37.287  28.329  40.854 1.00 41.62  ? 445 TYR F CB  1 
ATOM   16628 C CG  . TYR F 1 243 ? 36.637  29.666  41.076 1.00 43.81  ? 445 TYR F CG  1 
ATOM   16629 C CD1 . TYR F 1 243 ? 36.384  30.517  40.015 1.00 45.00  ? 445 TYR F CD1 1 
ATOM   16630 C CD2 . TYR F 1 243 ? 36.254  30.071  42.344 1.00 44.09  ? 445 TYR F CD2 1 
ATOM   16631 C CE1 . TYR F 1 243 ? 35.777  31.738  40.211 1.00 45.76  ? 445 TYR F CE1 1 
ATOM   16632 C CE2 . TYR F 1 243 ? 35.646  31.291  42.549 1.00 44.80  ? 445 TYR F CE2 1 
ATOM   16633 C CZ  . TYR F 1 243 ? 35.410  32.115  41.476 1.00 45.50  ? 445 TYR F CZ  1 
ATOM   16634 O OH  . TYR F 1 243 ? 34.809  33.329  41.671 1.00 46.64  ? 445 TYR F OH  1 
ATOM   16635 N N   . TYR F 1 244 ? 36.695  25.901  39.017 1.00 36.35  ? 446 TYR F N   1 
ATOM   16636 C CA  . TYR F 1 244 ? 37.195  24.811  38.186 1.00 36.70  ? 446 TYR F CA  1 
ATOM   16637 C C   . TYR F 1 244 ? 37.875  25.411  36.959 1.00 37.06  ? 446 TYR F C   1 
ATOM   16638 O O   . TYR F 1 244 ? 37.585  26.534  36.585 1.00 36.89  ? 446 TYR F O   1 
ATOM   16639 C CB  . TYR F 1 244 ? 36.090  23.812  37.816 1.00 32.27  ? 446 TYR F CB  1 
ATOM   16640 C CG  . TYR F 1 244 ? 35.095  24.302  36.795 1.00 32.65  ? 446 TYR F CG  1 
ATOM   16641 C CD1 . TYR F 1 244 ? 35.186  23.921  35.469 1.00 31.65  ? 446 TYR F CD1 1 
ATOM   16642 C CD2 . TYR F 1 244 ? 34.062  25.140  37.160 1.00 33.63  ? 446 TYR F CD2 1 
ATOM   16643 C CE1 . TYR F 1 244 ? 34.278  24.368  34.535 1.00 33.44  ? 446 TYR F CE1 1 
ATOM   16644 C CE2 . TYR F 1 244 ? 33.150  25.593  36.232 1.00 34.47  ? 446 TYR F CE2 1 
ATOM   16645 C CZ  . TYR F 1 244 ? 33.264  25.204  34.924 1.00 34.78  ? 446 TYR F CZ  1 
ATOM   16646 O OH  . TYR F 1 244 ? 32.351  25.659  34.010 1.00 35.38  ? 446 TYR F OH  1 
ATOM   16647 N N   . LEU F 1 245 ? 38.772  24.660  36.333 1.00 36.61  ? 447 LEU F N   1 
ATOM   16648 C CA  . LEU F 1 245 ? 39.514  25.151  35.179 1.00 38.28  ? 447 LEU F CA  1 
ATOM   16649 C C   . LEU F 1 245 ? 38.742  24.996  33.871 1.00 40.16  ? 447 LEU F C   1 
ATOM   16650 O O   . LEU F 1 245 ? 38.859  23.995  33.177 1.00 40.87  ? 447 LEU F O   1 
ATOM   16651 C CB  . LEU F 1 245 ? 40.842  24.404  35.092 1.00 40.41  ? 447 LEU F CB  1 
ATOM   16652 C CG  . LEU F 1 245 ? 41.816  24.760  33.975 1.00 40.71  ? 447 LEU F CG  1 
ATOM   16653 C CD1 . LEU F 1 245 ? 42.432  26.119  34.235 1.00 39.66  ? 447 LEU F CD1 1 
ATOM   16654 C CD2 . LEU F 1 245 ? 42.895  23.695  33.882 1.00 41.34  ? 447 LEU F CD2 1 
ATOM   16655 N N   . SER F 1 246 ? 37.940  26.008  33.564 1.00 40.15  ? 448 SER F N   1 
ATOM   16656 C CA  . SER F 1 246 ? 37.109  26.055  32.365 1.00 41.80  ? 448 SER F CA  1 
ATOM   16657 C C   . SER F 1 246 ? 37.790  26.118  30.993 1.00 43.43  ? 448 SER F C   1 
ATOM   16658 O O   . SER F 1 246 ? 37.338  25.465  30.060 1.00 44.72  ? 448 SER F O   1 
ATOM   16659 C CB  . SER F 1 246 ? 36.127  27.213  32.482 1.00 43.52  ? 448 SER F CB  1 
ATOM   16660 O OG  . SER F 1 246 ? 36.821  28.428  32.683 1.00 45.11  ? 448 SER F OG  1 
ATOM   16661 N N   . LYS F 1 247 ? 38.841  26.921  30.852 1.00 43.76  ? 449 LYS F N   1 
ATOM   16662 C CA  . LYS F 1 247 ? 39.528  27.048  29.565 1.00 45.39  ? 449 LYS F CA  1 
ATOM   16663 C C   . LYS F 1 247 ? 41.035  26.915  29.651 1.00 46.44  ? 449 LYS F C   1 
ATOM   16664 O O   . LYS F 1 247 ? 41.652  27.523  30.519 1.00 47.34  ? 449 LYS F O   1 
ATOM   16665 C CB  . LYS F 1 247 ? 39.231  28.408  28.944 1.00 48.76  ? 449 LYS F CB  1 
ATOM   16666 C CG  . LYS F 1 247 ? 37.917  28.514  28.203 1.00 51.13  ? 449 LYS F CG  1 
ATOM   16667 C CD  . LYS F 1 247 ? 37.780  29.902  27.600 1.00 53.93  ? 449 LYS F CD  1 
ATOM   16668 C CE  . LYS F 1 247 ? 36.344  30.191  27.202 1.00 56.71  ? 449 LYS F CE  1 
ATOM   16669 N NZ  . LYS F 1 247 ? 36.203  31.563  26.651 1.00 59.47  ? 449 LYS F NZ  1 
ATOM   16670 N N   . THR F 1 248 ? 41.635  26.130  28.760 1.00 47.76  ? 450 THR F N   1 
ATOM   16671 C CA  . THR F 1 248 ? 43.095  26.007  28.750 1.00 48.85  ? 450 THR F CA  1 
ATOM   16672 C C   . THR F 1 248 ? 43.783  26.670  27.549 1.00 50.10  ? 450 THR F C   1 
ATOM   16673 O O   . THR F 1 248 ? 45.001  26.658  27.461 1.00 50.08  ? 450 THR F O   1 
ATOM   16674 C CB  . THR F 1 248 ? 43.578  24.551  28.887 1.00 44.91  ? 450 THR F CB  1 
ATOM   16675 O OG1 . THR F 1 248 ? 43.296  23.830  27.685 1.00 45.57  ? 450 THR F OG1 1 
ATOM   16676 C CG2 . THR F 1 248 ? 42.908  23.879  30.061 1.00 44.09  ? 450 THR F CG2 1 
ATOM   16677 N N   . ILE F 1 249 ? 43.007  27.236  26.628 1.00 51.58  ? 451 ILE F N   1 
ATOM   16678 C CA  . ILE F 1 249 ? 43.553  27.910  25.447 1.00 53.37  ? 451 ILE F CA  1 
ATOM   16679 C C   . ILE F 1 249 ? 42.669  29.082  25.035 1.00 55.03  ? 451 ILE F C   1 
ATOM   16680 O O   . ILE F 1 249 ? 41.445  28.982  25.083 1.00 55.56  ? 451 ILE F O   1 
ATOM   16681 C CB  . ILE F 1 249 ? 43.611  26.992  24.209 1.00 51.29  ? 451 ILE F CB  1 
ATOM   16682 C CG1 . ILE F 1 249 ? 42.223  26.443  23.897 1.00 51.29  ? 451 ILE F CG1 1 
ATOM   16683 C CG2 . ILE F 1 249 ? 44.634  25.878  24.362 1.00 51.29  ? 451 ILE F CG2 1 
ATOM   16684 C CD1 . ILE F 1 249 ? 42.122  25.804  22.535 1.00 51.29  ? 451 ILE F CD1 1 
ATOM   16685 N N   . ASN F 1 250 ? 43.281  30.186  24.620 1.00 56.91  ? 452 ASN F N   1 
ATOM   16686 C CA  . ASN F 1 250 ? 42.520  31.347  24.171 1.00 59.28  ? 452 ASN F CA  1 
ATOM   16687 C C   . ASN F 1 250 ? 41.635  30.993  22.984 1.00 60.76  ? 452 ASN F C   1 
ATOM   16688 O O   . ASN F 1 250 ? 40.418  31.209  23.017 1.00 60.91  ? 452 ASN F O   1 
ATOM   16689 C CB  . ASN F 1 250 ? 43.465  32.491  23.802 1.00 55.51  ? 452 ASN F CB  1 
ATOM   16690 C CG  . ASN F 1 250 ? 44.233  33.027  24.992 1.00 57.71  ? 452 ASN F CG  1 
ATOM   16691 O OD1 . ASN F 1 250 ? 45.450  33.194  24.935 1.00 59.19  ? 452 ASN F OD1 1 
ATOM   16692 N ND2 . ASN F 1 250 ? 43.523  33.313  26.074 1.00 59.03  ? 452 ASN F ND2 1 
ATOM   16693 N N   . GLY F 1 251 ? 42.227  30.440  21.934 1.00 61.02  ? 453 GLY F N   1 
ATOM   16694 C CA  . GLY F 1 251 ? 41.482  30.102  20.741 1.00 63.37  ? 453 GLY F CA  1 
ATOM   16695 C C   . GLY F 1 251 ? 42.366  29.344  19.773 1.00 65.38  ? 453 GLY F C   1 
ATOM   16696 O O   . GLY F 1 251 ? 43.413  28.811  20.145 1.00 66.37  ? 453 GLY F O   1 
ATOM   16697 N N   . SER F 1 252 ? 41.916  29.297  18.523 1.00 68.68  ? 454 SER F N   1 
ATOM   16698 C CA  . SER F 1 252 ? 42.685  28.623  17.489 1.00 69.18  ? 454 SER F CA  1 
ATOM   16699 C C   . SER F 1 252 ? 43.931  29.428  17.141 1.00 68.43  ? 454 SER F C   1 
ATOM   16700 O O   . SER F 1 252 ? 43.870  30.643  16.939 1.00 67.91  ? 454 SER F O   1 
ATOM   16701 C CB  . SER F 1 252 ? 41.827  28.412  16.242 1.00 69.95  ? 454 SER F CB  1 
ATOM   16702 O OG  . SER F 1 252 ? 41.435  29.651  15.679 1.00 71.95  ? 454 SER F OG  1 
ATOM   16703 N N   . GLY F 1 253 ? 45.064  28.745  17.078 1.00 64.91  ? 455 GLY F N   1 
ATOM   16704 C CA  . GLY F 1 253 ? 46.321  29.362  16.729 1.00 64.32  ? 455 GLY F CA  1 
ATOM   16705 C C   . GLY F 1 253 ? 47.469  28.629  17.383 1.00 64.16  ? 455 GLY F C   1 
ATOM   16706 O O   . GLY F 1 253 ? 47.333  27.484  17.807 1.00 63.93  ? 455 GLY F O   1 
ATOM   16707 N N   . GLN F 1 254 ? 48.611  29.307  17.456 1.00 65.45  ? 456 GLN F N   1 
ATOM   16708 C CA  . GLN F 1 254 ? 49.810  28.782  18.093 1.00 65.88  ? 456 GLN F CA  1 
ATOM   16709 C C   . GLN F 1 254 ? 50.101  29.581  19.354 1.00 64.17  ? 456 GLN F C   1 
ATOM   16710 O O   . GLN F 1 254 ? 49.778  30.770  19.432 1.00 64.32  ? 456 GLN F O   1 
ATOM   16711 C CB  . GLN F 1 254 ? 51.015  28.848  17.151 1.00 63.82  ? 456 GLN F CB  1 
ATOM   16712 C CG  . GLN F 1 254 ? 50.898  27.971  15.918 1.00 69.58  ? 456 GLN F CG  1 
ATOM   16713 C CD  . GLN F 1 254 ? 50.851  26.497  16.258 1.00 72.94  ? 456 GLN F CD  1 
ATOM   16714 O OE1 . GLN F 1 254 ? 49.787  25.881  16.252 1.00 73.85  ? 456 GLN F OE1 1 
ATOM   16715 N NE2 . GLN F 1 254 ? 52.008  25.923  16.562 1.00 74.09  ? 456 GLN F NE2 1 
ATOM   16716 N N   . ASN F 1 255 ? 50.713  28.920  20.338 1.00 64.19  ? 457 ASN F N   1 
ATOM   16717 C CA  . ASN F 1 255 ? 51.065  29.552  21.612 1.00 62.45  ? 457 ASN F CA  1 
ATOM   16718 C C   . ASN F 1 255 ? 49.842  30.187  22.269 1.00 60.51  ? 457 ASN F C   1 
ATOM   16719 O O   . ASN F 1 255 ? 49.912  31.277  22.838 1.00 59.60  ? 457 ASN F O   1 
ATOM   16720 C CB  . ASN F 1 255 ? 52.181  30.582  21.429 1.00 59.86  ? 457 ASN F CB  1 
ATOM   16721 C CG  . ASN F 1 255 ? 53.509  29.944  21.084 1.00 61.14  ? 457 ASN F CG  1 
ATOM   16722 O OD1 . ASN F 1 255 ? 53.741  28.771  21.376 1.00 61.94  ? 457 ASN F OD1 1 
ATOM   16723 N ND2 . ASN F 1 255 ? 54.389  30.714  20.458 1.00 61.88  ? 457 ASN F ND2 1 
ATOM   16724 N N   . GLN F 1 256 ? 48.715  29.493  22.172 1.00 60.39  ? 458 GLN F N   1 
ATOM   16725 C CA  . GLN F 1 256 ? 47.461  29.972  22.730 1.00 58.63  ? 458 GLN F CA  1 
ATOM   16726 C C   . GLN F 1 256 ? 47.162  29.391  24.104 1.00 56.80  ? 458 GLN F C   1 
ATOM   16727 O O   . GLN F 1 256 ? 46.054  29.548  24.613 1.00 56.72  ? 458 GLN F O   1 
ATOM   16728 C CB  . GLN F 1 256 ? 46.313  29.640  21.782 1.00 59.03  ? 458 GLN F CB  1 
ATOM   16729 C CG  . GLN F 1 256 ? 46.415  30.325  20.434 1.00 61.63  ? 458 GLN F CG  1 
ATOM   16730 C CD  . GLN F 1 256 ? 46.061  31.793  20.511 1.00 64.02  ? 458 GLN F CD  1 
ATOM   16731 O OE1 . GLN F 1 256 ? 44.975  32.159  20.964 1.00 65.21  ? 458 GLN F OE1 1 
ATOM   16732 N NE2 . GLN F 1 256 ? 46.978  32.647  20.068 1.00 65.35  ? 458 GLN F NE2 1 
ATOM   16733 N N   . GLN F 1 257 ? 48.139  28.728  24.713 1.00 57.56  ? 459 GLN F N   1 
ATOM   16734 C CA  . GLN F 1 257 ? 47.901  28.146  26.024 1.00 55.65  ? 459 GLN F CA  1 
ATOM   16735 C C   . GLN F 1 257 ? 47.594  29.238  27.032 1.00 54.85  ? 459 GLN F C   1 
ATOM   16736 O O   . GLN F 1 257 ? 48.251  30.272  27.066 1.00 55.12  ? 459 GLN F O   1 
ATOM   16737 C CB  . GLN F 1 257 ? 49.108  27.341  26.509 1.00 54.84  ? 459 GLN F CB  1 
ATOM   16738 C CG  . GLN F 1 257 ? 49.494  26.172  25.626 1.00 55.69  ? 459 GLN F CG  1 
ATOM   16739 C CD  . GLN F 1 257 ? 50.738  26.438  24.806 1.00 55.06  ? 459 GLN F CD  1 
ATOM   16740 O OE1 . GLN F 1 257 ? 51.364  27.487  24.931 1.00 55.09  ? 459 GLN F OE1 1 
ATOM   16741 N NE2 . GLN F 1 257 ? 51.107  25.481  23.968 1.00 54.01  ? 459 GLN F NE2 1 
ATOM   16742 N N   . THR F 1 258 ? 46.571  29.007  27.839 1.00 52.97  ? 460 THR F N   1 
ATOM   16743 C CA  . THR F 1 258 ? 46.179  29.945  28.872 1.00 52.87  ? 460 THR F CA  1 
ATOM   16744 C C   . THR F 1 258 ? 45.341  29.211  29.895 1.00 51.01  ? 460 THR F C   1 
ATOM   16745 O O   . THR F 1 258 ? 44.801  28.151  29.598 1.00 51.36  ? 460 THR F O   1 
ATOM   16746 C CB  . THR F 1 258 ? 45.351  31.097  28.292 1.00 54.35  ? 460 THR F CB  1 
ATOM   16747 O OG1 . THR F 1 258 ? 45.006  32.006  29.341 1.00 53.98  ? 460 THR F OG1 1 
ATOM   16748 C CG2 . THR F 1 258 ? 44.085  30.567  27.658 1.00 56.48  ? 460 THR F CG2 1 
ATOM   16749 N N   . LEU F 1 259 ? 45.227  29.761  31.095 1.00 50.71  ? 461 LEU F N   1 
ATOM   16750 C CA  . LEU F 1 259 ? 44.405  29.145  32.129 1.00 47.91  ? 461 LEU F CA  1 
ATOM   16751 C C   . LEU F 1 259 ? 43.318  30.106  32.570 1.00 48.05  ? 461 LEU F C   1 
ATOM   16752 O O   . LEU F 1 259 ? 43.601  31.243  32.922 1.00 49.34  ? 461 LEU F O   1 
ATOM   16753 C CB  . LEU F 1 259 ? 45.249  28.734  33.332 1.00 50.60  ? 461 LEU F CB  1 
ATOM   16754 C CG  . LEU F 1 259 ? 45.710  27.282  33.412 1.00 48.46  ? 461 LEU F CG  1 
ATOM   16755 C CD1 . LEU F 1 259 ? 46.343  26.833  32.107 1.00 46.74  ? 461 LEU F CD1 1 
ATOM   16756 C CD2 . LEU F 1 259 ? 46.679  27.115  34.568 1.00 46.66  ? 461 LEU F CD2 1 
ATOM   16757 N N   . LYS F 1 260 ? 42.078  29.641  32.572 1.00 47.66  ? 462 LYS F N   1 
ATOM   16758 C CA  . LYS F 1 260 ? 40.958  30.470  32.975 1.00 47.09  ? 462 LYS F CA  1 
ATOM   16759 C C   . LYS F 1 260 ? 40.130  29.710  33.988 1.00 46.14  ? 462 LYS F C   1 
ATOM   16760 O O   . LYS F 1 260 ? 40.116  28.486  33.987 1.00 45.66  ? 462 LYS F O   1 
ATOM   16761 C CB  . LYS F 1 260 ? 40.106  30.830  31.768 1.00 48.83  ? 462 LYS F CB  1 
ATOM   16762 C CG  . LYS F 1 260 ? 40.867  31.547  30.666 1.00 50.60  ? 462 LYS F CG  1 
ATOM   16763 C CD  . LYS F 1 260 ? 41.452  32.860  31.156 1.00 51.40  ? 462 LYS F CD  1 
ATOM   16764 C CE  . LYS F 1 260 ? 42.157  33.598  30.034 1.00 53.56  ? 462 LYS F CE  1 
ATOM   16765 N NZ  . LYS F 1 260 ? 42.843  34.815  30.534 1.00 55.23  ? 462 LYS F NZ  1 
ATOM   16766 N N   . PHE F 1 261 ? 39.452  30.427  34.870 1.00 46.88  ? 463 PHE F N   1 
ATOM   16767 C CA  . PHE F 1 261 ? 38.639  29.771  35.881 1.00 45.51  ? 463 PHE F CA  1 
ATOM   16768 C C   . PHE F 1 261 ? 37.238  30.352  35.923 1.00 45.27  ? 463 PHE F C   1 
ATOM   16769 O O   . PHE F 1 261 ? 37.030  31.514  35.612 1.00 45.61  ? 463 PHE F O   1 
ATOM   16770 C CB  . PHE F 1 261 ? 39.311  29.858  37.250 1.00 45.59  ? 463 PHE F CB  1 
ATOM   16771 C CG  . PHE F 1 261 ? 40.605  29.103  37.335 1.00 44.07  ? 463 PHE F CG  1 
ATOM   16772 C CD1 . PHE F 1 261 ? 40.627  27.792  37.770 1.00 43.15  ? 463 PHE F CD1 1 
ATOM   16773 C CD2 . PHE F 1 261 ? 41.798  29.704  36.974 1.00 43.84  ? 463 PHE F CD2 1 
ATOM   16774 C CE1 . PHE F 1 261 ? 41.813  27.094  37.847 1.00 42.05  ? 463 PHE F CE1 1 
ATOM   16775 C CE2 . PHE F 1 261 ? 42.989  29.011  37.049 1.00 42.94  ? 463 PHE F CE2 1 
ATOM   16776 C CZ  . PHE F 1 261 ? 42.995  27.704  37.485 1.00 42.08  ? 463 PHE F CZ  1 
ATOM   16777 N N   . SER F 1 262 ? 36.268  29.517  36.266 1.00 41.02  ? 464 SER F N   1 
ATOM   16778 C CA  . SER F 1 262 ? 34.884  29.943  36.340 1.00 41.52  ? 464 SER F CA  1 
ATOM   16779 C C   . SER F 1 262 ? 34.221  29.366  37.572 1.00 41.66  ? 464 SER F C   1 
ATOM   16780 O O   . SER F 1 262 ? 34.690  28.393  38.142 1.00 41.57  ? 464 SER F O   1 
ATOM   16781 C CB  . SER F 1 262 ? 34.111  29.464  35.114 1.00 44.12  ? 464 SER F CB  1 
ATOM   16782 O OG  . SER F 1 262 ? 34.828  29.664  33.914 1.00 44.37  ? 464 SER F OG  1 
ATOM   16783 N N   . VAL F 1 263 ? 33.126  29.979  37.983 1.00 39.40  ? 465 VAL F N   1 
ATOM   16784 C CA  . VAL F 1 263 ? 32.356  29.503  39.123 1.00 40.64  ? 465 VAL F CA  1 
ATOM   16785 C C   . VAL F 1 263 ? 31.543  28.283  38.718 1.00 41.32  ? 465 VAL F C   1 
ATOM   16786 O O   . VAL F 1 263 ? 30.852  28.286  37.691 1.00 41.61  ? 465 VAL F O   1 
ATOM   16787 C CB  . VAL F 1 263 ? 31.444  30.619  39.659 1.00 38.91  ? 465 VAL F CB  1 
ATOM   16788 C CG1 . VAL F 1 263 ? 30.541  30.088  40.750 1.00 39.16  ? 465 VAL F CG1 1 
ATOM   16789 C CG2 . VAL F 1 263 ? 32.268  31.771  40.176 1.00 39.52  ? 465 VAL F CG2 1 
ATOM   16790 N N   . ALA F 1 264 ? 31.625  27.228  39.522 1.00 35.91  ? 466 ALA F N   1 
ATOM   16791 C CA  . ALA F 1 264 ? 30.752  26.078  39.345 1.00 37.13  ? 466 ALA F CA  1 
ATOM   16792 C C   . ALA F 1 264 ? 29.379  26.401  39.917 1.00 38.60  ? 466 ALA F C   1 
ATOM   16793 O O   . ALA F 1 264 ? 29.260  26.799  41.080 1.00 39.06  ? 466 ALA F O   1 
ATOM   16794 C CB  . ALA F 1 264 ? 31.341  24.844  40.024 1.00 34.80  ? 466 ALA F CB  1 
ATOM   16795 N N   . GLY F 1 265 ? 28.342  26.230  39.105 1.00 35.36  ? 467 GLY F N   1 
ATOM   16796 C CA  . GLY F 1 265 ? 27.022  26.663  39.486 1.00 36.20  ? 467 GLY F CA  1 
ATOM   16797 C C   . GLY F 1 265 ? 25.921  25.932  38.749 1.00 36.46  ? 467 GLY F C   1 
ATOM   16798 O O   . GLY F 1 265 ? 26.150  24.929  38.070 1.00 36.21  ? 467 GLY F O   1 
ATOM   16799 N N   . PRO F 1 266 ? 24.688  26.421  38.898 1.00 34.54  ? 468 PRO F N   1 
ATOM   16800 C CA  . PRO F 1 266 ? 23.553  25.783  38.214 1.00 34.93  ? 468 PRO F CA  1 
ATOM   16801 C C   . PRO F 1 266 ? 23.743  25.632  36.716 1.00 35.53  ? 468 PRO F C   1 
ATOM   16802 O O   . PRO F 1 266 ? 23.124  24.752  36.108 1.00 35.40  ? 468 PRO F O   1 
ATOM   16803 C CB  . PRO F 1 266 ? 22.389  26.728  38.535 1.00 33.75  ? 468 PRO F CB  1 
ATOM   16804 C CG  . PRO F 1 266 ? 22.780  27.379  39.804 1.00 33.67  ? 468 PRO F CG  1 
ATOM   16805 C CD  . PRO F 1 266 ? 24.260  27.533  39.760 1.00 34.04  ? 468 PRO F CD  1 
ATOM   16806 N N   . SER F 1 267 ? 24.570  26.477  36.098 1.00 35.22  ? 469 SER F N   1 
ATOM   16807 C CA  . SER F 1 267 ? 24.771  26.381  34.657 1.00 36.00  ? 469 SER F CA  1 
ATOM   16808 C C   . SER F 1 267 ? 25.378  25.038  34.274 1.00 35.96  ? 469 SER F C   1 
ATOM   16809 O O   . SER F 1 267 ? 24.820  24.309  33.446 1.00 36.16  ? 469 SER F O   1 
ATOM   16810 C CB  . SER F 1 267 ? 25.657  27.530  34.176 1.00 37.78  ? 469 SER F CB  1 
ATOM   16811 O OG  . SER F 1 267 ? 25.895  27.440  32.783 1.00 42.32  ? 469 SER F OG  1 
ATOM   16812 N N   . ASN F 1 268 ? 26.519  24.691  34.870 1.00 34.99  ? 470 ASN F N   1 
ATOM   16813 C CA  . ASN F 1 268 ? 27.211  23.428  34.617 1.00 33.71  ? 470 ASN F CA  1 
ATOM   16814 C C   . ASN F 1 268 ? 27.153  22.628  35.916 1.00 32.25  ? 470 ASN F C   1 
ATOM   16815 O O   . ASN F 1 268 ? 27.845  22.944  36.884 1.00 31.12  ? 470 ASN F O   1 
ATOM   16816 C CB  . ASN F 1 268 ? 28.650  23.692  34.156 1.00 31.60  ? 470 ASN F CB  1 
ATOM   16817 C CG  . ASN F 1 268 ? 29.359  22.442  33.672 1.00 34.24  ? 470 ASN F CG  1 
ATOM   16818 O OD1 . ASN F 1 268 ? 28.957  21.323  33.978 1.00 35.08  ? 470 ASN F OD1 1 
ATOM   16819 N ND2 . ASN F 1 268 ? 30.432  22.632  32.918 1.00 35.07  ? 470 ASN F ND2 1 
ATOM   16820 N N   . MET F 1 269 ? 26.329  21.579  35.932 1.00 30.72  ? 471 MET F N   1 
ATOM   16821 C CA  . MET F 1 269 ? 26.199  20.769  37.137 1.00 30.50  ? 471 MET F CA  1 
ATOM   16822 C C   . MET F 1 269 ? 27.148  19.584  37.157 1.00 29.30  ? 471 MET F C   1 
ATOM   16823 O O   . MET F 1 269 ? 27.283  18.934  38.197 1.00 29.97  ? 471 MET F O   1 
ATOM   16824 C CB  . MET F 1 269 ? 24.767  20.268  37.301 1.00 22.09  ? 471 MET F CB  1 
ATOM   16825 C CG  . MET F 1 269 ? 23.775  21.335  37.687 1.00 24.84  ? 471 MET F CG  1 
ATOM   16826 S SD  . MET F 1 269 ? 22.141  20.649  37.980 1.00 26.74  ? 471 MET F SD  1 
ATOM   16827 C CE  . MET F 1 269 ? 21.268  22.107  38.540 1.00 26.89  ? 471 MET F CE  1 
ATOM   16828 N N   . ALA F 1 270 ? 27.813  19.290  36.042 1.00 28.81  ? 472 ALA F N   1 
ATOM   16829 C CA  . ALA F 1 270 ? 28.677  18.118  36.005 1.00 27.10  ? 472 ALA F CA  1 
ATOM   16830 C C   . ALA F 1 270 ? 30.005  18.392  36.694 1.00 26.16  ? 472 ALA F C   1 
ATOM   16831 O O   . ALA F 1 270 ? 30.665  17.465  37.176 1.00 26.00  ? 472 ALA F O   1 
ATOM   16832 C CB  . ALA F 1 270 ? 28.899  17.679  34.560 1.00 26.51  ? 472 ALA F CB  1 
ATOM   16833 N N   . VAL F 1 271 ? 30.412  19.664  36.756 1.00 27.48  ? 473 VAL F N   1 
ATOM   16834 C CA  . VAL F 1 271 ? 31.747  20.014  37.227 1.00 26.33  ? 473 VAL F CA  1 
ATOM   16835 C C   . VAL F 1 271 ? 31.788  20.409  38.696 1.00 24.82  ? 473 VAL F C   1 
ATOM   16836 O O   . VAL F 1 271 ? 32.855  20.804  39.185 1.00 24.32  ? 473 VAL F O   1 
ATOM   16837 C CB  . VAL F 1 271 ? 32.339  21.151  36.373 1.00 25.97  ? 473 VAL F CB  1 
ATOM   16838 C CG1 . VAL F 1 271 ? 32.518  20.690  34.946 1.00 30.32  ? 473 VAL F CG1 1 
ATOM   16839 C CG2 . VAL F 1 271 ? 31.442  22.363  36.428 1.00 26.57  ? 473 VAL F CG2 1 
ATOM   16840 N N   . GLN F 1 272 ? 30.673  20.330  39.417 1.00 28.45  ? 474 GLN F N   1 
ATOM   16841 C CA  . GLN F 1 272 ? 30.685  20.757  40.809 1.00 27.02  ? 474 GLN F CA  1 
ATOM   16842 C C   . GLN F 1 272 ? 31.446  19.766  41.679 1.00 26.56  ? 474 GLN F C   1 
ATOM   16843 O O   . GLN F 1 272 ? 31.500  18.569  41.392 1.00 27.06  ? 474 GLN F O   1 
ATOM   16844 C CB  . GLN F 1 272 ? 29.269  20.910  41.354 1.00 24.86  ? 474 GLN F CB  1 
ATOM   16845 C CG  . GLN F 1 272 ? 28.425  21.947  40.672 1.00 27.90  ? 474 GLN F CG  1 
ATOM   16846 C CD  . GLN F 1 272 ? 27.122  22.142  41.397 1.00 29.53  ? 474 GLN F CD  1 
ATOM   16847 O OE1 . GLN F 1 272 ? 26.747  21.321  42.228 1.00 30.77  ? 474 GLN F OE1 1 
ATOM   16848 N NE2 . GLN F 1 272 ? 26.410  23.210  41.074 1.00 31.21  ? 474 GLN F NE2 1 
ATOM   16849 N N   . GLY F 1 273 ? 32.035  20.279  42.756 1.00 26.98  ? 475 GLY F N   1 
ATOM   16850 C CA  . GLY F 1 273 ? 32.663  19.408  43.729 1.00 25.84  ? 475 GLY F CA  1 
ATOM   16851 C C   . GLY F 1 273 ? 31.625  18.689  44.570 1.00 26.60  ? 475 GLY F C   1 
ATOM   16852 O O   . GLY F 1 273 ? 30.661  19.285  45.052 1.00 27.05  ? 475 GLY F O   1 
ATOM   16853 N N   . ARG F 1 274 ? 31.836  17.392  44.761 1.00 24.96  ? 476 ARG F N   1 
ATOM   16854 C CA  . ARG F 1 274 ? 30.874  16.556  45.457 1.00 24.71  ? 476 ARG F CA  1 
ATOM   16855 C C   . ARG F 1 274 ? 31.545  15.797  46.591 1.00 24.45  ? 476 ARG F C   1 
ATOM   16856 O O   . ARG F 1 274 ? 32.689  15.353  46.479 1.00 25.54  ? 476 ARG F O   1 
ATOM   16857 C CB  . ARG F 1 274 ? 30.195  15.576  44.498 1.00 17.32  ? 476 ARG F CB  1 
ATOM   16858 C CG  . ARG F 1 274 ? 29.289  16.254  43.499 1.00 18.87  ? 476 ARG F CG  1 
ATOM   16859 C CD  . ARG F 1 274 ? 28.675  15.264  42.542 1.00 20.22  ? 476 ARG F CD  1 
ATOM   16860 N NE  . ARG F 1 274 ? 27.752  15.914  41.620 1.00 24.45  ? 476 ARG F NE  1 
ATOM   16861 C CZ  . ARG F 1 274 ? 28.125  16.543  40.513 1.00 25.32  ? 476 ARG F CZ  1 
ATOM   16862 N NH1 . ARG F 1 274 ? 29.406  16.610  40.189 1.00 28.13  ? 476 ARG F NH1 1 
ATOM   16863 N NH2 . ARG F 1 274 ? 27.219  17.105  39.730 1.00 27.42  ? 476 ARG F NH2 1 
ATOM   16864 N N   . ASN F 1 275 ? 30.801  15.647  47.686 1.00 25.37  ? 477 ASN F N   1 
ATOM   16865 C CA  . ASN F 1 275 ? 31.314  14.988  48.879 1.00 24.74  ? 477 ASN F CA  1 
ATOM   16866 C C   . ASN F 1 275 ? 31.380  13.477  48.728 1.00 24.38  ? 477 ASN F C   1 
ATOM   16867 O O   . ASN F 1 275 ? 32.182  12.832  49.409 1.00 23.40  ? 477 ASN F O   1 
ATOM   16868 C CB  . ASN F 1 275 ? 30.438  15.351  50.075 1.00 27.59  ? 477 ASN F CB  1 
ATOM   16869 C CG  . ASN F 1 275 ? 30.631  16.779  50.516 1.00 29.11  ? 477 ASN F CG  1 
ATOM   16870 O OD1 . ASN F 1 275 ? 31.722  17.326  50.402 1.00 31.43  ? 477 ASN F OD1 1 
ATOM   16871 N ND2 . ASN F 1 275 ? 29.558  17.410  50.973 1.00 29.45  ? 477 ASN F ND2 1 
ATOM   16872 N N   . TYR F 1 276 ? 30.555  12.896  47.862 1.00 18.38  ? 478 TYR F N   1 
ATOM   16873 C CA  . TYR F 1 276 ? 30.461  11.451  47.743 1.00 19.44  ? 478 TYR F CA  1 
ATOM   16874 C C   . TYR F 1 276 ? 30.418  11.036  46.281 1.00 20.52  ? 478 TYR F C   1 
ATOM   16875 O O   . TYR F 1 276 ? 29.986  11.796  45.413 1.00 22.65  ? 478 TYR F O   1 
ATOM   16876 C CB  . TYR F 1 276 ? 29.235  10.919  48.487 1.00 20.19  ? 478 TYR F CB  1 
ATOM   16877 C CG  . TYR F 1 276 ? 29.318  11.190  49.967 1.00 22.40  ? 478 TYR F CG  1 
ATOM   16878 C CD1 . TYR F 1 276 ? 30.037  10.351  50.802 1.00 22.90  ? 478 TYR F CD1 1 
ATOM   16879 C CD2 . TYR F 1 276 ? 28.687  12.289  50.528 1.00 21.59  ? 478 TYR F CD2 1 
ATOM   16880 C CE1 . TYR F 1 276 ? 30.132  10.601  52.148 1.00 23.14  ? 478 TYR F CE1 1 
ATOM   16881 C CE2 . TYR F 1 276 ? 28.774  12.544  51.878 1.00 23.44  ? 478 TYR F CE2 1 
ATOM   16882 C CZ  . TYR F 1 276 ? 29.499  11.696  52.682 1.00 24.26  ? 478 TYR F CZ  1 
ATOM   16883 O OH  . TYR F 1 276 ? 29.589  11.940  54.028 1.00 25.81  ? 478 TYR F OH  1 
ATOM   16884 N N   . ILE F 1 277 ? 30.880  9.816   46.027 1.00 17.38  ? 479 ILE F N   1 
ATOM   16885 C CA  . ILE F 1 277 ? 31.030  9.285   44.674 1.00 16.77  ? 479 ILE F CA  1 
ATOM   16886 C C   . ILE F 1 277 ? 30.301  7.950   44.604 1.00 17.93  ? 479 ILE F C   1 
ATOM   16887 O O   . ILE F 1 277 ? 30.078  7.296   45.635 1.00 18.30  ? 479 ILE F O   1 
ATOM   16888 C CB  . ILE F 1 277 ? 32.519  9.129   44.290 1.00 19.74  ? 479 ILE F CB  1 
ATOM   16889 C CG1 . ILE F 1 277 ? 33.226  8.219   45.292 1.00 18.11  ? 479 ILE F CG1 1 
ATOM   16890 C CG2 . ILE F 1 277 ? 33.188  10.483  44.202 1.00 18.56  ? 479 ILE F CG2 1 
ATOM   16891 C CD1 . ILE F 1 277 ? 34.619  7.835   44.887 1.00 16.62  ? 479 ILE F CD1 1 
ATOM   16892 N N   . PRO F 1 278 ? 29.909  7.516   43.404 1.00 16.72  ? 480 PRO F N   1 
ATOM   16893 C CA  . PRO F 1 278 ? 29.104  6.296   43.294 1.00 17.16  ? 480 PRO F CA  1 
ATOM   16894 C C   . PRO F 1 278 ? 29.880  5.056   43.709 1.00 17.84  ? 480 PRO F C   1 
ATOM   16895 O O   . PRO F 1 278 ? 31.109  5.044   43.778 1.00 17.32  ? 480 PRO F O   1 
ATOM   16896 C CB  . PRO F 1 278 ? 28.728  6.254   41.811 1.00 16.97  ? 480 PRO F CB  1 
ATOM   16897 C CG  . PRO F 1 278 ? 29.803  6.988   41.147 1.00 17.42  ? 480 PRO F CG  1 
ATOM   16898 C CD  . PRO F 1 278 ? 30.164  8.101   42.080 1.00 16.20  ? 480 PRO F CD  1 
ATOM   16899 N N   . GLY F 1 279 ? 29.129  3.992   43.978 1.00 15.05  ? 481 GLY F N   1 
ATOM   16900 C CA  . GLY F 1 279 ? 29.672  2.779   44.531 1.00 16.12  ? 481 GLY F CA  1 
ATOM   16901 C C   . GLY F 1 279 ? 30.598  2.043   43.589 1.00 16.99  ? 481 GLY F C   1 
ATOM   16902 O O   . GLY F 1 279 ? 30.834  2.463   42.454 1.00 17.54  ? 481 GLY F O   1 
ATOM   16903 N N   . PRO F 1 280 ? 31.139  0.918   44.051 1.00 16.05  ? 482 PRO F N   1 
ATOM   16904 C CA  . PRO F 1 280 ? 32.117  0.181   43.246 1.00 16.60  ? 482 PRO F CA  1 
ATOM   16905 C C   . PRO F 1 280 ? 31.479  -0.439  42.014 1.00 17.60  ? 482 PRO F C   1 
ATOM   16906 O O   . PRO F 1 280 ? 30.256  -0.556  41.915 1.00 17.70  ? 482 PRO F O   1 
ATOM   16907 C CB  . PRO F 1 280 ? 32.625  -0.888  44.214 1.00 18.17  ? 482 PRO F CB  1 
ATOM   16908 C CG  . PRO F 1 280 ? 31.494  -1.095  45.139 1.00 18.04  ? 482 PRO F CG  1 
ATOM   16909 C CD  . PRO F 1 280 ? 30.855  0.240   45.326 1.00 17.73  ? 482 PRO F CD  1 
ATOM   16910 N N   . SER F 1 281 ? 32.325  -0.835  41.067 1.00 18.91  ? 483 SER F N   1 
ATOM   16911 C CA  . SER F 1 281 ? 31.878  -1.415  39.810 1.00 19.77  ? 483 SER F CA  1 
ATOM   16912 C C   . SER F 1 281 ? 32.833  -2.512  39.367 1.00 19.19  ? 483 SER F C   1 
ATOM   16913 O O   . SER F 1 281 ? 34.050  -2.379  39.502 1.00 19.63  ? 483 SER F O   1 
ATOM   16914 C CB  . SER F 1 281 ? 31.778  -0.350  38.717 1.00 17.76  ? 483 SER F CB  1 
ATOM   16915 O OG  . SER F 1 281 ? 31.398  -0.925  37.481 1.00 20.20  ? 483 SER F OG  1 
ATOM   16916 N N   . TYR F 1 282 ? 32.268  -3.604  38.863 1.00 20.90  ? 484 TYR F N   1 
ATOM   16917 C CA  . TYR F 1 282 ? 33.010  -4.657  38.183 1.00 18.93  ? 484 TYR F CA  1 
ATOM   16918 C C   . TYR F 1 282 ? 32.230  -4.993  36.921 1.00 18.35  ? 484 TYR F C   1 
ATOM   16919 O O   . TYR F 1 282 ? 31.152  -5.585  37.002 1.00 18.62  ? 484 TYR F O   1 
ATOM   16920 C CB  . TYR F 1 282 ? 33.135  -5.878  39.096 1.00 23.41  ? 484 TYR F CB  1 
ATOM   16921 C CG  . TYR F 1 282 ? 33.988  -7.009  38.592 1.00 22.35  ? 484 TYR F CG  1 
ATOM   16922 C CD1 . TYR F 1 282 ? 35.356  -7.015  38.805 1.00 22.21  ? 484 TYR F CD1 1 
ATOM   16923 C CD2 . TYR F 1 282 ? 33.429  -8.075  37.911 1.00 21.67  ? 484 TYR F CD2 1 
ATOM   16924 C CE1 . TYR F 1 282 ? 36.141  -8.053  38.365 1.00 21.31  ? 484 TYR F CE1 1 
ATOM   16925 C CE2 . TYR F 1 282 ? 34.206  -9.115  37.457 1.00 20.76  ? 484 TYR F CE2 1 
ATOM   16926 C CZ  . TYR F 1 282 ? 35.562  -9.099  37.687 1.00 21.26  ? 484 TYR F CZ  1 
ATOM   16927 O OH  . TYR F 1 282 ? 36.341  -10.137 37.236 1.00 20.95  ? 484 TYR F OH  1 
ATOM   16928 N N   . ARG F 1 283 ? 32.780  -4.660  35.759 1.00 18.59  ? 485 ARG F N   1 
ATOM   16929 C CA  . ARG F 1 283 ? 31.941  -4.471  34.582 1.00 18.08  ? 485 ARG F CA  1 
ATOM   16930 C C   . ARG F 1 283 ? 31.455  -5.797  34.011 1.00 18.16  ? 485 ARG F C   1 
ATOM   16931 O O   . ARG F 1 283 ? 32.175  -6.798  34.032 1.00 17.75  ? 485 ARG F O   1 
ATOM   16932 C CB  . ARG F 1 283 ? 32.686  -3.675  33.515 1.00 18.63  ? 485 ARG F CB  1 
ATOM   16933 C CG  . ARG F 1 283 ? 31.860  -3.361  32.287 1.00 20.23  ? 485 ARG F CG  1 
ATOM   16934 C CD  . ARG F 1 283 ? 32.613  -2.448  31.364 1.00 19.67  ? 485 ARG F CD  1 
ATOM   16935 N NE  . ARG F 1 283 ? 31.857  -2.090  30.174 1.00 20.34  ? 485 ARG F NE  1 
ATOM   16936 C CZ  . ARG F 1 283 ? 32.245  -1.167  29.304 1.00 19.77  ? 485 ARG F CZ  1 
ATOM   16937 N NH1 . ARG F 1 283 ? 33.379  -0.512  29.493 1.00 18.78  ? 485 ARG F NH1 1 
ATOM   16938 N NH2 . ARG F 1 283 ? 31.500  -0.898  28.246 1.00 21.98  ? 485 ARG F NH2 1 
ATOM   16939 N N   . GLN F 1 284 ? 30.227  -5.787  33.499 1.00 17.75  ? 486 GLN F N   1 
ATOM   16940 C CA  . GLN F 1 284 ? 29.578  -6.926  32.869 1.00 18.30  ? 486 GLN F CA  1 
ATOM   16941 C C   . GLN F 1 284 ? 29.446  -6.686  31.370 1.00 19.10  ? 486 GLN F C   1 
ATOM   16942 O O   . GLN F 1 284 ? 29.399  -5.546  30.907 1.00 18.72  ? 486 GLN F O   1 
ATOM   16943 C CB  . GLN F 1 284 ? 28.185  -7.164  33.460 1.00 18.22  ? 486 GLN F CB  1 
ATOM   16944 C CG  . GLN F 1 284 ? 28.121  -7.660  34.897 1.00 20.10  ? 486 GLN F CG  1 
ATOM   16945 C CD  . GLN F 1 284 ? 28.696  -9.045  35.070 1.00 21.96  ? 486 GLN F CD  1 
ATOM   16946 O OE1 . GLN F 1 284 ? 28.552  -9.900  34.201 1.00 23.16  ? 486 GLN F OE1 1 
ATOM   16947 N NE2 . GLN F 1 284 ? 29.332  -9.283  36.208 1.00 22.84  ? 486 GLN F NE2 1 
ATOM   16948 N N   . GLN F 1 285 ? 29.400  -7.777  30.611 1.00 19.33  ? 487 GLN F N   1 
ATOM   16949 C CA  . GLN F 1 285 ? 29.104  -7.684  29.188 1.00 19.39  ? 487 GLN F CA  1 
ATOM   16950 C C   . GLN F 1 285 ? 27.605  -7.527  28.974 1.00 19.82  ? 487 GLN F C   1 
ATOM   16951 O O   . GLN F 1 285 ? 26.795  -8.119  29.691 1.00 19.91  ? 487 GLN F O   1 
ATOM   16952 C CB  . GLN F 1 285 ? 29.626  -8.919  28.458 1.00 21.75  ? 487 GLN F CB  1 
ATOM   16953 C CG  . GLN F 1 285 ? 29.409  -8.902  26.958 1.00 21.66  ? 487 GLN F CG  1 
ATOM   16954 C CD  . GLN F 1 285 ? 30.094  -7.736  26.286 1.00 22.19  ? 487 GLN F CD  1 
ATOM   16955 O OE1 . GLN F 1 285 ? 29.452  -6.758  25.919 1.00 19.53  ? 487 GLN F OE1 1 
ATOM   16956 N NE2 . GLN F 1 285 ? 31.406  -7.827  26.132 1.00 22.36  ? 487 GLN F NE2 1 
ATOM   16957 N N   . ARG F 1 286 ? 27.234  -6.728  27.980 1.00 20.12  ? 488 ARG F N   1 
ATOM   16958 C CA  . ARG F 1 286 ? 25.852  -6.313  27.791 1.00 20.07  ? 488 ARG F CA  1 
ATOM   16959 C C   . ARG F 1 286 ? 25.184  -7.180  26.734 1.00 20.01  ? 488 ARG F C   1 
ATOM   16960 O O   . ARG F 1 286 ? 25.696  -7.312  25.620 1.00 21.68  ? 488 ARG F O   1 
ATOM   16961 C CB  . ARG F 1 286 ? 25.786  -4.845  27.380 1.00 17.12  ? 488 ARG F CB  1 
ATOM   16962 C CG  . ARG F 1 286 ? 24.389  -4.279  27.386 1.00 18.22  ? 488 ARG F CG  1 
ATOM   16963 C CD  . ARG F 1 286 ? 24.355  -2.860  26.867 1.00 20.54  ? 488 ARG F CD  1 
ATOM   16964 N NE  . ARG F 1 286 ? 24.678  -2.807  25.447 1.00 23.68  ? 488 ARG F NE  1 
ATOM   16965 C CZ  . ARG F 1 286 ? 24.924  -1.687  24.781 1.00 26.35  ? 488 ARG F CZ  1 
ATOM   16966 N NH1 . ARG F 1 286 ? 24.877  -0.521  25.405 1.00 24.21  ? 488 ARG F NH1 1 
ATOM   16967 N NH2 . ARG F 1 286 ? 25.201  -1.732  23.488 1.00 29.53  ? 488 ARG F NH2 1 
ATOM   16968 N N   . VAL F 1 287 ? 24.039  -7.756  27.085 1.00 18.18  ? 489 VAL F N   1 
ATOM   16969 C CA  . VAL F 1 287 ? 23.261  -8.602  26.188 1.00 17.77  ? 489 VAL F CA  1 
ATOM   16970 C C   . VAL F 1 287 ? 21.891  -7.967  26.005 1.00 18.29  ? 489 VAL F C   1 
ATOM   16971 O O   . VAL F 1 287 ? 21.286  -7.489  26.970 1.00 19.33  ? 489 VAL F O   1 
ATOM   16972 C CB  . VAL F 1 287 ? 23.137  -10.038 26.735 1.00 17.86  ? 489 VAL F CB  1 
ATOM   16973 C CG1 . VAL F 1 287 ? 22.286  -10.892 25.817 1.00 16.79  ? 489 VAL F CG1 1 
ATOM   16974 C CG2 . VAL F 1 287 ? 24.505  -10.652 26.915 1.00 18.70  ? 489 VAL F CG2 1 
ATOM   16975 N N   . SER F 1 288 ? 21.404  -7.955  24.770 1.00 18.91  ? 490 SER F N   1 
ATOM   16976 C CA  . SER F 1 288 ? 20.102  -7.387  24.463 1.00 19.36  ? 490 SER F CA  1 
ATOM   16977 C C   . SER F 1 288 ? 19.066  -8.490  24.317 1.00 20.26  ? 490 SER F C   1 
ATOM   16978 O O   . SER F 1 288 ? 19.360  -9.587  23.839 1.00 18.84  ? 490 SER F O   1 
ATOM   16979 C CB  . SER F 1 288 ? 20.144  -6.560  23.179 1.00 20.01  ? 490 SER F CB  1 
ATOM   16980 O OG  . SER F 1 288 ? 20.405  -7.381  22.060 1.00 20.08  ? 490 SER F OG  1 
ATOM   16981 N N   . THR F 1 289 ? 17.842  -8.187  24.752 1.00 19.56  ? 491 THR F N   1 
ATOM   16982 C CA  . THR F 1 289 ? 16.748  -9.138  24.597 1.00 22.09  ? 491 THR F CA  1 
ATOM   16983 C C   . THR F 1 289 ? 16.433  -9.372  23.125 1.00 23.92  ? 491 THR F C   1 
ATOM   16984 O O   . THR F 1 289 ? 16.025  -10.472 22.736 1.00 25.02  ? 491 THR F O   1 
ATOM   16985 C CB  . THR F 1 289 ? 15.518  -8.639  25.353 1.00 25.96  ? 491 THR F CB  1 
ATOM   16986 O OG1 . THR F 1 289 ? 15.833  -8.527  26.745 1.00 29.36  ? 491 THR F OG1 1 
ATOM   16987 C CG2 . THR F 1 289 ? 14.358  -9.599  25.195 1.00 24.85  ? 491 THR F CG2 1 
ATOM   16988 N N   . THR F 1 290 ? 16.636  -8.358  22.288 1.00 22.65  ? 492 THR F N   1 
ATOM   16989 C CA  . THR F 1 290 ? 16.512  -8.527  20.847 1.00 23.74  ? 492 THR F CA  1 
ATOM   16990 C C   . THR F 1 290 ? 17.771  -9.206  20.330 1.00 23.47  ? 492 THR F C   1 
ATOM   16991 O O   . THR F 1 290 ? 18.873  -8.665  20.463 1.00 23.59  ? 492 THR F O   1 
ATOM   16992 C CB  . THR F 1 290 ? 16.308  -7.181  20.159 1.00 24.09  ? 492 THR F CB  1 
ATOM   16993 O OG1 . THR F 1 290 ? 15.098  -6.577  20.632 1.00 26.45  ? 492 THR F OG1 1 
ATOM   16994 C CG2 . THR F 1 290 ? 16.225  -7.363  18.656 1.00 23.93  ? 492 THR F CG2 1 
ATOM   16995 N N   . VAL F 1 291 ? 17.611  -10.384 19.731 1.00 22.99  ? 493 VAL F N   1 
ATOM   16996 C CA  . VAL F 1 291 ? 18.769  -11.231 19.471 1.00 22.76  ? 493 VAL F CA  1 
ATOM   16997 C C   . VAL F 1 291 ? 19.545  -10.731 18.262 1.00 22.25  ? 493 VAL F C   1 
ATOM   16998 O O   . VAL F 1 291 ? 20.764  -10.912 18.174 1.00 22.12  ? 493 VAL F O   1 
ATOM   16999 C CB  . VAL F 1 291 ? 18.331  -12.696 19.305 1.00 20.31  ? 493 VAL F CB  1 
ATOM   17000 C CG1 . VAL F 1 291 ? 17.708  -13.193 20.589 1.00 21.97  ? 493 VAL F CG1 1 
ATOM   17001 C CG2 . VAL F 1 291 ? 17.355  -12.832 18.155 1.00 20.18  ? 493 VAL F CG2 1 
ATOM   17002 N N   . THR F 1 292 ? 18.862  -10.086 17.315 1.00 25.06  ? 494 THR F N   1 
ATOM   17003 C CA  . THR F 1 292 ? 19.552  -9.589  16.131 1.00 24.49  ? 494 THR F CA  1 
ATOM   17004 C C   . THR F 1 292 ? 20.539  -8.485  16.478 1.00 24.27  ? 494 THR F C   1 
ATOM   17005 O O   . THR F 1 292 ? 21.415  -8.157  15.672 1.00 24.38  ? 494 THR F O   1 
ATOM   17006 C CB  . THR F 1 292 ? 18.540  -9.087  15.102 1.00 25.47  ? 494 THR F CB  1 
ATOM   17007 O OG1 . THR F 1 292 ? 17.747  -8.044  15.679 1.00 25.73  ? 494 THR F OG1 1 
ATOM   17008 C CG2 . THR F 1 292 ? 17.635  -10.218 14.662 1.00 24.51  ? 494 THR F CG2 1 
ATOM   17009 N N   . GLN F 1 293 ? 20.416  -7.902  17.671 1.00 23.95  ? 495 GLN F N   1 
ATOM   17010 C CA  . GLN F 1 293 ? 21.350  -6.866  18.091 1.00 23.11  ? 495 GLN F CA  1 
ATOM   17011 C C   . GLN F 1 293 ? 22.622  -7.461  18.676 1.00 22.70  ? 495 GLN F C   1 
ATOM   17012 O O   . GLN F 1 293 ? 23.635  -6.763  18.784 1.00 23.12  ? 495 GLN F O   1 
ATOM   17013 C CB  . GLN F 1 293 ? 20.673  -5.944  19.100 1.00 21.44  ? 495 GLN F CB  1 
ATOM   17014 C CG  . GLN F 1 293 ? 19.518  -5.164  18.511 1.00 23.92  ? 495 GLN F CG  1 
ATOM   17015 C CD  . GLN F 1 293 ? 18.780  -4.343  19.542 1.00 25.79  ? 495 GLN F CD  1 
ATOM   17016 O OE1 . GLN F 1 293 ? 18.805  -4.651  20.731 1.00 27.57  ? 495 GLN F OE1 1 
ATOM   17017 N NE2 . GLN F 1 293 ? 18.110  -3.293  19.090 1.00 27.14  ? 495 GLN F NE2 1 
ATOM   17018 N N   . ASN F 1 294 ? 22.586  -8.732  19.064 1.00 23.95  ? 496 ASN F N   1 
ATOM   17019 C CA  . ASN F 1 294 ? 23.765  -9.416  19.567 1.00 23.27  ? 496 ASN F CA  1 
ATOM   17020 C C   . ASN F 1 294 ? 24.641  -9.895  18.413 1.00 23.81  ? 496 ASN F C   1 
ATOM   17021 O O   . ASN F 1 294 ? 24.175  -10.112 17.293 1.00 23.74  ? 496 ASN F O   1 
ATOM   17022 C CB  . ASN F 1 294 ? 23.362  -10.604 20.436 1.00 20.63  ? 496 ASN F CB  1 
ATOM   17023 C CG  . ASN F 1 294 ? 22.709  -10.184 21.731 1.00 20.66  ? 496 ASN F CG  1 
ATOM   17024 O OD1 . ASN F 1 294 ? 22.927  -9.082  22.222 1.00 19.40  ? 496 ASN F OD1 1 
ATOM   17025 N ND2 . ASN F 1 294 ? 21.900  -11.068 22.294 1.00 21.95  ? 496 ASN F ND2 1 
ATOM   17026 N N   . ASN F 1 295 ? 25.915  -10.071 18.737 1.00 26.64  ? 497 ASN F N   1 
ATOM   17027 C CA  . ASN F 1 295 ? 26.929  -10.530 17.812 1.00 27.40  ? 497 ASN F CA  1 
ATOM   17028 C C   . ASN F 1 295 ? 26.695  -11.993 17.508 1.00 28.28  ? 497 ASN F C   1 
ATOM   17029 O O   . ASN F 1 295 ? 26.304  -12.757 18.378 1.00 28.02  ? 497 ASN F O   1 
ATOM   17030 C CB  . ASN F 1 295 ? 28.304  -10.350 18.444 1.00 28.71  ? 497 ASN F CB  1 
ATOM   17031 C CG  . ASN F 1 295 ? 29.431  -10.638 17.482 1.00 29.94  ? 497 ASN F CG  1 
ATOM   17032 O OD1 . ASN F 1 295 ? 30.184  -11.583 17.665 1.00 30.38  ? 497 ASN F OD1 1 
ATOM   17033 N ND2 . ASN F 1 295 ? 29.543  -9.830  16.445 1.00 30.18  ? 497 ASN F ND2 1 
ATOM   17034 N N   . ASN F 1 296 ? 26.981  -12.395 16.278 1.00 26.58  ? 498 ASN F N   1 
ATOM   17035 C CA  . ASN F 1 296 ? 26.777  -13.766 15.852 1.00 27.73  ? 498 ASN F CA  1 
ATOM   17036 C C   . ASN F 1 296 ? 27.943  -14.653 16.251 1.00 28.44  ? 498 ASN F C   1 
ATOM   17037 O O   . ASN F 1 296 ? 28.727  -15.072 15.410 1.00 29.00  ? 498 ASN F O   1 
ATOM   17038 C CB  . ASN F 1 296 ? 26.640  -13.784 14.340 1.00 32.01  ? 498 ASN F CB  1 
ATOM   17039 C CG  . ASN F 1 296 ? 26.096  -15.086 13.822 1.00 32.12  ? 498 ASN F CG  1 
ATOM   17040 O OD1 . ASN F 1 296 ? 24.958  -15.440 14.093 1.00 31.83  ? 498 ASN F OD1 1 
ATOM   17041 N ND2 . ASN F 1 296 ? 26.904  -15.801 13.058 1.00 33.08  ? 498 ASN F ND2 1 
ATOM   17042 N N   . SER F 1 297 ? 28.055  -14.937 17.541 1.00 28.80  ? 499 SER F N   1 
ATOM   17043 C CA  . SER F 1 297 ? 29.127  -15.776 18.048 1.00 29.68  ? 499 SER F CA  1 
ATOM   17044 C C   . SER F 1 297 ? 28.735  -16.372 19.383 1.00 29.83  ? 499 SER F C   1 
ATOM   17045 O O   . SER F 1 297 ? 27.780  -15.929 20.006 1.00 29.51  ? 499 SER F O   1 
ATOM   17046 C CB  . SER F 1 297 ? 30.420  -14.977 18.191 1.00 31.32  ? 499 SER F CB  1 
ATOM   17047 O OG  . SER F 1 297 ? 30.369  -14.106 19.303 1.00 32.21  ? 499 SER F OG  1 
ATOM   17048 N N   . GLU F 1 298 ? 29.460  -17.391 19.817 1.00 28.16  ? 500 GLU F N   1 
ATOM   17049 C CA  . GLU F 1 298 ? 29.170  -17.998 21.099 1.00 28.67  ? 500 GLU F CA  1 
ATOM   17050 C C   . GLU F 1 298 ? 29.979  -17.267 22.156 1.00 27.90  ? 500 GLU F C   1 
ATOM   17051 O O   . GLU F 1 298 ? 31.148  -17.567 22.363 1.00 28.31  ? 500 GLU F O   1 
ATOM   17052 C CB  . GLU F 1 298 ? 29.562  -19.470 21.071 1.00 25.99  ? 500 GLU F CB  1 
ATOM   17053 C CG  . GLU F 1 298 ? 29.504  -20.143 22.425 1.00 30.06  ? 500 GLU F CG  1 
ATOM   17054 C CD  . GLU F 1 298 ? 28.151  -19.993 23.079 1.00 32.42  ? 500 GLU F CD  1 
ATOM   17055 O OE1 . GLU F 1 298 ? 27.135  -20.277 22.414 1.00 33.68  ? 500 GLU F OE1 1 
ATOM   17056 O OE2 . GLU F 1 298 ? 28.110  -19.591 24.256 1.00 32.53  ? 500 GLU F OE2 1 
ATOM   17057 N N   . PHE F 1 299 ? 29.355  -16.297 22.816 1.00 30.18  ? 501 PHE F N   1 
ATOM   17058 C CA  . PHE F 1 299 ? 30.031  -15.514 23.845 1.00 29.11  ? 501 PHE F CA  1 
ATOM   17059 C C   . PHE F 1 299 ? 29.545  -15.679 25.283 1.00 28.65  ? 501 PHE F C   1 
ATOM   17060 O O   . PHE F 1 299 ? 29.932  -14.899 26.139 1.00 28.87  ? 501 PHE F O   1 
ATOM   17061 C CB  . PHE F 1 299 ? 30.065  -14.032 23.464 1.00 27.60  ? 501 PHE F CB  1 
ATOM   17062 C CG  . PHE F 1 299 ? 28.720  -13.360 23.457 1.00 26.77  ? 501 PHE F CG  1 
ATOM   17063 C CD1 . PHE F 1 299 ? 28.113  -12.980 24.638 1.00 26.39  ? 501 PHE F CD1 1 
ATOM   17064 C CD2 . PHE F 1 299 ? 28.086  -13.070 22.267 1.00 26.45  ? 501 PHE F CD2 1 
ATOM   17065 C CE1 . PHE F 1 299 ? 26.889  -12.349 24.633 1.00 25.92  ? 501 PHE F CE1 1 
ATOM   17066 C CE2 . PHE F 1 299 ? 26.861  -12.437 22.253 1.00 25.85  ? 501 PHE F CE2 1 
ATOM   17067 C CZ  . PHE F 1 299 ? 26.261  -12.078 23.438 1.00 25.58  ? 501 PHE F CZ  1 
ATOM   17068 N N   . ALA F 1 300 ? 28.700  -16.668 25.554 1.00 30.07  ? 502 ALA F N   1 
ATOM   17069 C CA  . ALA F 1 300 ? 28.183  -16.867 26.907 1.00 29.12  ? 502 ALA F CA  1 
ATOM   17070 C C   . ALA F 1 300 ? 29.302  -17.006 27.929 1.00 28.93  ? 502 ALA F C   1 
ATOM   17071 O O   . ALA F 1 300 ? 29.417  -16.201 28.837 1.00 28.85  ? 502 ALA F O   1 
ATOM   17072 C CB  . ALA F 1 300 ? 27.256  -18.064 26.957 1.00 26.44  ? 502 ALA F CB  1 
ATOM   17073 N N   . TRP F 1 301 ? 30.111  -18.044 27.793 1.00 29.57  ? 503 TRP F N   1 
ATOM   17074 C CA  . TRP F 1 301 ? 31.248  -18.248 28.681 1.00 30.11  ? 503 TRP F CA  1 
ATOM   17075 C C   . TRP F 1 301 ? 32.470  -17.422 28.273 1.00 29.79  ? 503 TRP F C   1 
ATOM   17076 O O   . TRP F 1 301 ? 33.064  -16.762 29.136 1.00 29.77  ? 503 TRP F O   1 
ATOM   17077 C CB  . TRP F 1 301 ? 31.607  -19.730 28.775 1.00 28.61  ? 503 TRP F CB  1 
ATOM   17078 C CG  . TRP F 1 301 ? 32.782  -19.965 29.656 1.00 31.88  ? 503 TRP F CG  1 
ATOM   17079 C CD1 . TRP F 1 301 ? 34.028  -20.356 29.273 1.00 32.74  ? 503 TRP F CD1 1 
ATOM   17080 C CD2 . TRP F 1 301 ? 32.840  -19.769 31.072 1.00 33.46  ? 503 TRP F CD2 1 
ATOM   17081 N NE1 . TRP F 1 301 ? 34.853  -20.445 30.367 1.00 33.38  ? 503 TRP F NE1 1 
ATOM   17082 C CE2 . TRP F 1 301 ? 34.146  -20.087 31.484 1.00 33.74  ? 503 TRP F CE2 1 
ATOM   17083 C CE3 . TRP F 1 301 ? 31.909  -19.367 32.034 1.00 34.23  ? 503 TRP F CE3 1 
ATOM   17084 C CZ2 . TRP F 1 301 ? 34.546  -20.015 32.815 1.00 34.52  ? 503 TRP F CZ2 1 
ATOM   17085 C CZ3 . TRP F 1 301 ? 32.307  -19.298 33.352 1.00 34.84  ? 503 TRP F CZ3 1 
ATOM   17086 C CH2 . TRP F 1 301 ? 33.613  -19.619 33.732 1.00 35.04  ? 503 TRP F CH2 1 
ATOM   17087 N N   . PRO F 1 302 ? 32.895  -17.432 26.997 1.00 29.92  ? 504 PRO F N   1 
ATOM   17088 C CA  . PRO F 1 302 ? 34.120  -16.686 26.647 1.00 29.65  ? 504 PRO F CA  1 
ATOM   17089 C C   . PRO F 1 302 ? 34.070  -15.207 26.986 1.00 30.09  ? 504 PRO F C   1 
ATOM   17090 O O   . PRO F 1 302 ? 35.064  -14.658 27.476 1.00 31.66  ? 504 PRO F O   1 
ATOM   17091 C CB  . PRO F 1 302 ? 34.237  -16.909 25.135 1.00 28.32  ? 504 PRO F CB  1 
ATOM   17092 C CG  . PRO F 1 302 ? 33.559  -18.191 24.900 1.00 27.64  ? 504 PRO F CG  1 
ATOM   17093 C CD  . PRO F 1 302 ? 32.400  -18.203 25.842 1.00 29.04  ? 504 PRO F CD  1 
ATOM   17094 N N   . GLY F 1 303 ? 32.940  -14.541 26.744 1.00 28.08  ? 505 GLY F N   1 
ATOM   17095 C CA  . GLY F 1 303 ? 32.878  -13.109 26.986 1.00 28.38  ? 505 GLY F CA  1 
ATOM   17096 C C   . GLY F 1 303 ? 32.375  -12.765 28.374 1.00 28.02  ? 505 GLY F C   1 
ATOM   17097 O O   . GLY F 1 303 ? 32.046  -11.610 28.654 1.00 28.95  ? 505 GLY F O   1 
ATOM   17098 N N   . ALA F 1 304 ? 32.314  -13.752 29.260 1.00 26.58  ? 506 ALA F N   1 
ATOM   17099 C CA  . ALA F 1 304 ? 31.775  -13.537 30.592 1.00 25.35  ? 506 ALA F CA  1 
ATOM   17100 C C   . ALA F 1 304 ? 32.811  -12.899 31.513 1.00 24.68  ? 506 ALA F C   1 
ATOM   17101 O O   . ALA F 1 304 ? 34.021  -13.037 31.328 1.00 25.53  ? 506 ALA F O   1 
ATOM   17102 C CB  . ALA F 1 304 ? 31.298  -14.857 31.188 1.00 25.41  ? 506 ALA F CB  1 
ATOM   17103 N N   . SER F 1 305 ? 32.314  -12.188 32.521 1.00 26.34  ? 507 SER F N   1 
ATOM   17104 C CA  . SER F 1 305 ? 33.147  -11.670 33.596 1.00 25.18  ? 507 SER F CA  1 
ATOM   17105 C C   . SER F 1 305 ? 33.296  -12.732 34.673 1.00 24.13  ? 507 SER F C   1 
ATOM   17106 O O   . SER F 1 305 ? 32.304  -13.261 35.179 1.00 23.63  ? 507 SER F O   1 
ATOM   17107 C CB  . SER F 1 305 ? 32.534  -10.405 34.194 1.00 23.77  ? 507 SER F CB  1 
ATOM   17108 O OG  . SER F 1 305 ? 32.475  -9.363  33.241 1.00 25.76  ? 507 SER F OG  1 
ATOM   17109 N N   . SER F 1 306 ? 34.539  -13.037 35.029 1.00 26.21  ? 508 SER F N   1 
ATOM   17110 C CA  . SER F 1 306 ? 34.807  -14.164 35.906 1.00 25.27  ? 508 SER F CA  1 
ATOM   17111 C C   . SER F 1 306 ? 35.851  -13.781 36.940 1.00 24.46  ? 508 SER F C   1 
ATOM   17112 O O   . SER F 1 306 ? 36.486  -12.728 36.854 1.00 24.99  ? 508 SER F O   1 
ATOM   17113 C CB  . SER F 1 306 ? 35.273  -15.386 35.110 1.00 28.65  ? 508 SER F CB  1 
ATOM   17114 O OG  . SER F 1 306 ? 36.495  -15.119 34.451 1.00 28.74  ? 508 SER F OG  1 
ATOM   17115 N N   . TRP F 1 307 ? 35.999  -14.644 37.938 1.00 28.96  ? 509 TRP F N   1 
ATOM   17116 C CA  . TRP F 1 307 ? 37.080  -14.548 38.902 1.00 28.40  ? 509 TRP F CA  1 
ATOM   17117 C C   . TRP F 1 307 ? 37.724  -15.913 39.080 1.00 27.98  ? 509 TRP F C   1 
ATOM   17118 O O   . TRP F 1 307 ? 37.041  -16.935 39.163 1.00 26.37  ? 509 TRP F O   1 
ATOM   17119 C CB  . TRP F 1 307 ? 36.605  -13.992 40.254 1.00 27.77  ? 509 TRP F CB  1 
ATOM   17120 C CG  . TRP F 1 307 ? 35.382  -14.637 40.839 1.00 28.44  ? 509 TRP F CG  1 
ATOM   17121 C CD1 . TRP F 1 307 ? 34.094  -14.229 40.681 1.00 28.90  ? 509 TRP F CD1 1 
ATOM   17122 C CD2 . TRP F 1 307 ? 35.333  -15.795 41.680 1.00 28.81  ? 509 TRP F CD2 1 
ATOM   17123 N NE1 . TRP F 1 307 ? 33.245  -15.054 41.371 1.00 29.49  ? 509 TRP F NE1 1 
ATOM   17124 C CE2 . TRP F 1 307 ? 33.982  -16.028 41.990 1.00 29.41  ? 509 TRP F CE2 1 
ATOM   17125 C CE3 . TRP F 1 307 ? 36.300  -16.662 42.194 1.00 29.25  ? 509 TRP F CE3 1 
ATOM   17126 C CZ2 . TRP F 1 307 ? 33.572  -17.085 42.794 1.00 29.93  ? 509 TRP F CZ2 1 
ATOM   17127 C CZ3 . TRP F 1 307 ? 35.891  -17.710 42.995 1.00 30.01  ? 509 TRP F CZ3 1 
ATOM   17128 C CH2 . TRP F 1 307 ? 34.539  -17.912 43.287 1.00 30.58  ? 509 TRP F CH2 1 
ATOM   17129 N N   . ALA F 1 308 ? 39.052  -15.916 39.126 1.00 30.64  ? 510 ALA F N   1 
ATOM   17130 C CA  . ALA F 1 308 ? 39.837  -17.137 39.206 1.00 30.99  ? 510 ALA F CA  1 
ATOM   17131 C C   . ALA F 1 308 ? 40.204  -17.435 40.651 1.00 31.97  ? 510 ALA F C   1 
ATOM   17132 O O   . ALA F 1 308 ? 40.662  -16.552 41.381 1.00 33.20  ? 510 ALA F O   1 
ATOM   17133 C CB  . ALA F 1 308 ? 41.109  -17.029 38.363 1.00 36.55  ? 510 ALA F CB  1 
ATOM   17134 N N   . LEU F 1 309 ? 40.004  -18.686 41.056 1.00 36.90  ? 511 LEU F N   1 
ATOM   17135 C CA  . LEU F 1 309 ? 40.341  -19.135 42.400 1.00 37.48  ? 511 LEU F CA  1 
ATOM   17136 C C   . LEU F 1 309 ? 41.088  -20.453 42.291 1.00 38.65  ? 511 LEU F C   1 
ATOM   17137 O O   . LEU F 1 309 ? 40.528  -21.440 41.806 1.00 38.46  ? 511 LEU F O   1 
ATOM   17138 C CB  . LEU F 1 309 ? 39.082  -19.299 43.251 1.00 37.66  ? 511 LEU F CB  1 
ATOM   17139 C CG  . LEU F 1 309 ? 39.282  -19.727 44.699 1.00 37.72  ? 511 LEU F CG  1 
ATOM   17140 C CD1 . LEU F 1 309 ? 40.008  -18.635 45.455 1.00 37.89  ? 511 LEU F CD1 1 
ATOM   17141 C CD2 . LEU F 1 309 ? 37.950  -20.046 45.337 1.00 37.58  ? 511 LEU F CD2 1 
ATOM   17142 N N   . ASN F 1 310 ? 42.349  -20.464 42.726 1.00 39.49  ? 512 ASN F N   1 
ATOM   17143 C CA  . ASN F 1 310 ? 43.172  -21.676 42.744 1.00 41.32  ? 512 ASN F CA  1 
ATOM   17144 C C   . ASN F 1 310 ? 43.282  -22.294 41.351 1.00 41.97  ? 512 ASN F C   1 
ATOM   17145 O O   . ASN F 1 310 ? 43.438  -23.506 41.192 1.00 42.48  ? 512 ASN F O   1 
ATOM   17146 C CB  . ASN F 1 310 ? 42.627  -22.687 43.756 1.00 47.84  ? 512 ASN F CB  1 
ATOM   17147 C CG  . ASN F 1 310 ? 43.608  -23.803 44.058 1.00 50.11  ? 512 ASN F CG  1 
ATOM   17148 O OD1 . ASN F 1 310 ? 44.821  -23.610 44.000 1.00 52.06  ? 512 ASN F OD1 1 
ATOM   17149 N ND2 . ASN F 1 310 ? 43.086  -24.978 44.384 1.00 49.44  ? 512 ASN F ND2 1 
ATOM   17150 N N   . GLY F 1 311 ? 43.199  -21.450 40.325 1.00 35.80  ? 513 GLY F N   1 
ATOM   17151 C CA  . GLY F 1 311 ? 43.284  -21.903 38.955 1.00 35.78  ? 513 GLY F CA  1 
ATOM   17152 C C   . GLY F 1 311 ? 41.957  -22.124 38.263 1.00 36.62  ? 513 GLY F C   1 
ATOM   17153 O O   . GLY F 1 311 ? 41.921  -22.152 37.027 1.00 37.92  ? 513 GLY F O   1 
ATOM   17154 N N   . ARG F 1 312 ? 40.870  -22.283 39.009 1.00 38.42  ? 514 ARG F N   1 
ATOM   17155 C CA  . ARG F 1 312 ? 39.544  -22.467 38.441 1.00 38.81  ? 514 ARG F CA  1 
ATOM   17156 C C   . ARG F 1 312 ? 38.869  -21.118 38.249 1.00 38.56  ? 514 ARG F C   1 
ATOM   17157 O O   . ARG F 1 312 ? 38.944  -20.242 39.113 1.00 39.08  ? 514 ARG F O   1 
ATOM   17158 C CB  . ARG F 1 312 ? 38.675  -23.353 39.336 1.00 38.00  ? 514 ARG F CB  1 
ATOM   17159 C CG  . ARG F 1 312 ? 39.107  -24.802 39.390 1.00 42.00  ? 514 ARG F CG  1 
ATOM   17160 C CD  . ARG F 1 312 ? 38.314  -25.564 40.427 1.00 46.05  ? 514 ARG F CD  1 
ATOM   17161 N NE  . ARG F 1 312 ? 38.568  -25.049 41.766 1.00 50.24  ? 514 ARG F NE  1 
ATOM   17162 C CZ  . ARG F 1 312 ? 38.019  -25.541 42.869 1.00 52.66  ? 514 ARG F CZ  1 
ATOM   17163 N NH1 . ARG F 1 312 ? 37.184  -26.565 42.794 1.00 53.30  ? 514 ARG F NH1 1 
ATOM   17164 N NH2 . ARG F 1 312 ? 38.308  -25.009 44.047 1.00 53.67  ? 514 ARG F NH2 1 
ATOM   17165 N N   . ASN F 1 313 ? 38.198  -20.959 37.114 1.00 38.81  ? 515 ASN F N   1 
ATOM   17166 C CA  . ASN F 1 313 ? 37.525  -19.712 36.783 1.00 38.02  ? 515 ASN F CA  1 
ATOM   17167 C C   . ASN F 1 313 ? 36.036  -19.850 37.048 1.00 36.61  ? 515 ASN F C   1 
ATOM   17168 O O   . ASN F 1 313 ? 35.330  -20.549 36.315 1.00 36.81  ? 515 ASN F O   1 
ATOM   17169 C CB  . ASN F 1 313 ? 37.763  -19.328 35.323 1.00 38.92  ? 515 ASN F CB  1 
ATOM   17170 C CG  . ASN F 1 313 ? 39.184  -18.896 35.061 1.00 40.53  ? 515 ASN F CG  1 
ATOM   17171 O OD1 . ASN F 1 313 ? 39.580  -17.784 35.401 1.00 41.39  ? 515 ASN F OD1 1 
ATOM   17172 N ND2 . ASN F 1 313 ? 39.963  -19.775 34.448 1.00 42.39  ? 515 ASN F ND2 1 
ATOM   17173 N N   . SER F 1 314 ? 35.545  -19.153 38.063 1.00 30.49  ? 516 SER F N   1 
ATOM   17174 C CA  . SER F 1 314 ? 34.126  -19.163 38.384 1.00 29.52  ? 516 SER F CA  1 
ATOM   17175 C C   . SER F 1 314 ? 33.504  -17.901 37.825 1.00 29.18  ? 516 SER F C   1 
ATOM   17176 O O   . SER F 1 314 ? 34.083  -16.834 37.914 1.00 28.84  ? 516 SER F O   1 
ATOM   17177 C CB  . SER F 1 314 ? 33.917  -19.189 39.892 1.00 33.49  ? 516 SER F CB  1 
ATOM   17178 O OG  . SER F 1 314 ? 34.670  -20.223 40.492 1.00 34.87  ? 516 SER F OG  1 
ATOM   17179 N N   . LEU F 1 315 ? 32.324  -18.016 37.242 1.00 26.74  ? 517 LEU F N   1 
ATOM   17180 C CA  . LEU F 1 315 ? 31.648  -16.856 36.686 1.00 27.05  ? 517 LEU F CA  1 
ATOM   17181 C C   . LEU F 1 315 ? 31.284  -15.883 37.796 1.00 27.48  ? 517 LEU F C   1 
ATOM   17182 O O   . LEU F 1 315 ? 30.899  -16.299 38.882 1.00 28.33  ? 517 LEU F O   1 
ATOM   17183 C CB  . LEU F 1 315 ? 30.380  -17.306 35.970 1.00 26.65  ? 517 LEU F CB  1 
ATOM   17184 C CG  . LEU F 1 315 ? 29.647  -16.294 35.103 1.00 27.42  ? 517 LEU F CG  1 
ATOM   17185 C CD1 . LEU F 1 315 ? 30.349  -16.172 33.765 1.00 27.23  ? 517 LEU F CD1 1 
ATOM   17186 C CD2 . LEU F 1 315 ? 28.211  -16.737 34.903 1.00 29.27  ? 517 LEU F CD2 1 
ATOM   17187 N N   . MET F 1 316 ? 31.388  -14.588 37.524 1.00 27.70  ? 518 MET F N   1 
ATOM   17188 C CA  . MET F 1 316 ? 31.039  -13.565 38.506 1.00 27.61  ? 518 MET F CA  1 
ATOM   17189 C C   . MET F 1 316 ? 29.535  -13.346 38.407 1.00 27.41  ? 518 MET F C   1 
ATOM   17190 O O   . MET F 1 316 ? 29.073  -12.419 37.759 1.00 27.23  ? 518 MET F O   1 
ATOM   17191 C CB  . MET F 1 316 ? 31.796  -12.269 38.214 1.00 27.49  ? 518 MET F CB  1 
ATOM   17192 C CG  . MET F 1 316 ? 31.365  -11.078 39.047 1.00 28.85  ? 518 MET F CG  1 
ATOM   17193 S SD  . MET F 1 316 ? 32.073  -11.064 40.700 1.00 31.54  ? 518 MET F SD  1 
ATOM   17194 C CE  . MET F 1 316 ? 33.607  -10.191 40.434 1.00 29.30  ? 518 MET F CE  1 
ATOM   17195 N N   . ASN F 1 317 ? 28.789  -14.234 39.053 1.00 27.24  ? 519 ASN F N   1 
ATOM   17196 C CA  . ASN F 1 317 ? 27.337  -14.247 39.040 1.00 26.65  ? 519 ASN F CA  1 
ATOM   17197 C C   . ASN F 1 317 ? 26.803  -14.218 40.455 1.00 26.43  ? 519 ASN F C   1 
ATOM   17198 O O   . ASN F 1 317 ? 27.192  -15.040 41.264 1.00 27.21  ? 519 ASN F O   1 
ATOM   17199 C CB  . ASN F 1 317 ? 26.907  -15.555 38.382 1.00 27.18  ? 519 ASN F CB  1 
ATOM   17200 C CG  . ASN F 1 317 ? 25.419  -15.655 38.172 1.00 27.62  ? 519 ASN F CG  1 
ATOM   17201 O OD1 . ASN F 1 317 ? 24.691  -14.675 38.280 1.00 29.97  ? 519 ASN F OD1 1 
ATOM   17202 N ND2 . ASN F 1 317 ? 24.958  -16.853 37.857 1.00 26.36  ? 519 ASN F ND2 1 
ATOM   17203 N N   . PRO F 1 318 ? 25.871  -13.307 40.760 1.00 25.63  ? 520 PRO F N   1 
ATOM   17204 C CA  . PRO F 1 318 ? 25.562  -12.011 40.152 1.00 25.44  ? 520 PRO F CA  1 
ATOM   17205 C C   . PRO F 1 318 ? 26.722  -11.032 40.294 1.00 25.98  ? 520 PRO F C   1 
ATOM   17206 O O   . PRO F 1 318 ? 26.934  -10.207 39.417 1.00 25.74  ? 520 PRO F O   1 
ATOM   17207 C CB  . PRO F 1 318 ? 24.345  -11.537 40.938 1.00 25.41  ? 520 PRO F CB  1 
ATOM   17208 C CG  . PRO F 1 318 ? 24.462  -12.218 42.245 1.00 25.42  ? 520 PRO F CG  1 
ATOM   17209 C CD  . PRO F 1 318 ? 25.029  -13.564 41.937 1.00 26.24  ? 520 PRO F CD  1 
ATOM   17210 N N   . GLY F 1 319 ? 27.423  -11.085 41.418 1.00 25.06  ? 521 GLY F N   1 
ATOM   17211 C CA  . GLY F 1 319 ? 28.554  -10.211 41.648 1.00 26.08  ? 521 GLY F CA  1 
ATOM   17212 C C   . GLY F 1 319 ? 28.094  -9.026  42.451 1.00 26.90  ? 521 GLY F C   1 
ATOM   17213 O O   . GLY F 1 319 ? 27.114  -9.126  43.178 1.00 27.39  ? 521 GLY F O   1 
ATOM   17214 N N   . PRO F 1 320 ? 28.781  -7.882  42.310 1.00 25.46  ? 522 PRO F N   1 
ATOM   17215 C CA  . PRO F 1 320 ? 28.422  -6.653  43.021 1.00 25.19  ? 522 PRO F CA  1 
ATOM   17216 C C   . PRO F 1 320 ? 27.087  -6.108  42.541 1.00 24.90  ? 522 PRO F C   1 
ATOM   17217 O O   . PRO F 1 320 ? 26.652  -6.363  41.417 1.00 25.98  ? 522 PRO F O   1 
ATOM   17218 C CB  . PRO F 1 320 ? 29.569  -5.699  42.676 1.00 26.25  ? 522 PRO F CB  1 
ATOM   17219 C CG  . PRO F 1 320 ? 30.715  -6.598  42.377 1.00 27.57  ? 522 PRO F CG  1 
ATOM   17220 C CD  . PRO F 1 320 ? 30.116  -7.794  41.698 1.00 26.99  ? 522 PRO F CD  1 
ATOM   17221 N N   . ALA F 1 321 ? 26.438  -5.342  43.411 1.00 19.83  ? 523 ALA F N   1 
ATOM   17222 C CA  . ALA F 1 321 ? 25.140  -4.767  43.090 1.00 19.63  ? 523 ALA F CA  1 
ATOM   17223 C C   . ALA F 1 321 ? 25.336  -3.547  42.205 1.00 19.74  ? 523 ALA F C   1 
ATOM   17224 O O   . ALA F 1 321 ? 25.978  -2.573  42.611 1.00 19.43  ? 523 ALA F O   1 
ATOM   17225 C CB  . ALA F 1 321 ? 24.394  -4.394  44.367 1.00 19.27  ? 523 ALA F CB  1 
ATOM   17226 N N   . MET F 1 322 ? 24.781  -3.598  40.998 1.00 15.76  ? 524 MET F N   1 
ATOM   17227 C CA  . MET F 1 322 ? 24.898  -2.514  40.036 1.00 16.59  ? 524 MET F CA  1 
ATOM   17228 C C   . MET F 1 322 ? 23.610  -2.414  39.239 1.00 17.01  ? 524 MET F C   1 
ATOM   17229 O O   . MET F 1 322 ? 22.930  -3.414  39.004 1.00 18.60  ? 524 MET F O   1 
ATOM   17230 C CB  . MET F 1 322 ? 26.075  -2.724  39.082 1.00 13.45  ? 524 MET F CB  1 
ATOM   17231 C CG  . MET F 1 322 ? 27.432  -2.620  39.733 1.00 16.15  ? 524 MET F CG  1 
ATOM   17232 S SD  . MET F 1 322 ? 28.744  -2.898  38.545 1.00 19.74  ? 524 MET F SD  1 
ATOM   17233 C CE  . MET F 1 322 ? 28.570  -4.659  38.318 1.00 21.82  ? 524 MET F CE  1 
ATOM   17234 N N   . ALA F 1 323 ? 23.281  -1.192  38.830 1.00 13.27  ? 525 ALA F N   1 
ATOM   17235 C CA  . ALA F 1 323 ? 22.124  -0.977  37.976 1.00 14.27  ? 525 ALA F CA  1 
ATOM   17236 C C   . ALA F 1 323 ? 22.260  -1.797  36.701 1.00 15.64  ? 525 ALA F C   1 
ATOM   17237 O O   . ALA F 1 323 ? 23.311  -1.792  36.057 1.00 16.10  ? 525 ALA F O   1 
ATOM   17238 C CB  . ALA F 1 323 ? 21.982  0.506   37.647 1.00 16.26  ? 525 ALA F CB  1 
ATOM   17239 N N   . SER F 1 324 ? 21.222  -2.555  36.387 1.00 16.75  ? 526 SER F N   1 
ATOM   17240 C CA  . SER F 1 324 ? 21.238  -3.444  35.242 1.00 18.54  ? 526 SER F CA  1 
ATOM   17241 C C   . SER F 1 324 ? 21.421  -2.765  33.909 1.00 19.71  ? 526 SER F C   1 
ATOM   17242 O O   . SER F 1 324 ? 22.053  -3.304  33.014 1.00 19.86  ? 526 SER F O   1 
ATOM   17243 C CB  . SER F 1 324 ? 19.962  -4.273  35.218 1.00 17.38  ? 526 SER F CB  1 
ATOM   17244 O OG  . SER F 1 324 ? 19.938  -5.180  36.301 1.00 20.11  ? 526 SER F OG  1 
ATOM   17245 N N   . HIS F 1 325 ? 20.859  -1.580  33.770 1.00 17.69  ? 527 HIS F N   1 
ATOM   17246 C CA  . HIS F 1 325 ? 20.950  -0.876  32.514 1.00 20.17  ? 527 HIS F CA  1 
ATOM   17247 C C   . HIS F 1 325 ? 20.764  0.602   32.711 1.00 21.71  ? 527 HIS F C   1 
ATOM   17248 O O   . HIS F 1 325 ? 20.293  1.040   33.750 1.00 21.73  ? 527 HIS F O   1 
ATOM   17249 C CB  . HIS F 1 325 ? 19.853  -1.384  31.593 1.00 23.12  ? 527 HIS F CB  1 
ATOM   17250 C CG  . HIS F 1 325 ? 18.505  -1.438  32.241 1.00 23.94  ? 527 HIS F CG  1 
ATOM   17251 N ND1 . HIS F 1 325 ? 17.706  -0.327  32.386 1.00 24.50  ? 527 HIS F ND1 1 
ATOM   17252 C CD2 . HIS F 1 325 ? 17.816  -2.468  32.783 1.00 23.97  ? 527 HIS F CD2 1 
ATOM   17253 C CE1 . HIS F 1 325 ? 16.585  -0.668  32.995 1.00 23.56  ? 527 HIS F CE1 1 
ATOM   17254 N NE2 . HIS F 1 325 ? 16.627  -1.962  33.247 1.00 23.50  ? 527 HIS F NE2 1 
ATOM   17255 N N   . LYS F 1 326 ? 21.137  1.378   31.702 1.00 23.13  ? 528 LYS F N   1 
ATOM   17256 C CA  . LYS F 1 326 ? 20.934  2.820   31.732 1.00 25.89  ? 528 LYS F CA  1 
ATOM   17257 C C   . LYS F 1 326 ? 19.445  3.103   31.565 1.00 27.89  ? 528 LYS F C   1 
ATOM   17258 O O   . LYS F 1 326 ? 18.725  2.327   30.944 1.00 27.41  ? 528 LYS F O   1 
ATOM   17259 C CB  . LYS F 1 326 ? 21.726  3.514   30.629 1.00 21.49  ? 528 LYS F CB  1 
ATOM   17260 C CG  . LYS F 1 326 ? 23.183  3.730   30.965 1.00 22.09  ? 528 LYS F CG  1 
ATOM   17261 C CD  . LYS F 1 326 ? 23.858  4.617   29.938 1.00 24.27  ? 528 LYS F CD  1 
ATOM   17262 C CE  . LYS F 1 326 ? 23.987  3.915   28.602 1.00 24.67  ? 528 LYS F CE  1 
ATOM   17263 N NZ  . LYS F 1 326 ? 24.881  4.679   27.693 1.00 25.07  ? 528 LYS F NZ  1 
ATOM   17264 N N   . GLU F 1 327 ? 18.981  4.231   32.082 1.00 28.03  ? 529 GLU F N   1 
ATOM   17265 C CA  . GLU F 1 327 ? 17.568  4.563   31.988 1.00 31.75  ? 529 GLU F CA  1 
ATOM   17266 C C   . GLU F 1 327 ? 17.149  4.641   30.532 1.00 32.46  ? 529 GLU F C   1 
ATOM   17267 O O   . GLU F 1 327 ? 17.848  5.216   29.703 1.00 32.50  ? 529 GLU F O   1 
ATOM   17268 C CB  . GLU F 1 327 ? 17.305  5.899   32.673 1.00 31.61  ? 529 GLU F CB  1 
ATOM   17269 C CG  . GLU F 1 327 ? 15.844  6.198   32.941 1.00 37.39  ? 529 GLU F CG  1 
ATOM   17270 C CD  . GLU F 1 327 ? 15.666  7.176   34.084 1.00 40.40  ? 529 GLU F CD  1 
ATOM   17271 O OE1 . GLU F 1 327 ? 14.538  7.289   34.599 1.00 40.79  ? 529 GLU F OE1 1 
ATOM   17272 O OE2 . GLU F 1 327 ? 16.659  7.821   34.475 1.00 42.35  ? 529 GLU F OE2 1 
ATOM   17273 N N   . GLY F 1 328 ? 15.991  4.067   30.230 1.00 33.99  ? 530 GLY F N   1 
ATOM   17274 C CA  . GLY F 1 328 ? 15.499  4.044   28.870 1.00 34.72  ? 530 GLY F CA  1 
ATOM   17275 C C   . GLY F 1 328 ? 16.061  2.913   28.029 1.00 35.21  ? 530 GLY F C   1 
ATOM   17276 O O   . GLY F 1 328 ? 15.908  2.915   26.811 1.00 36.17  ? 530 GLY F O   1 
ATOM   17277 N N   . GLU F 1 329 ? 16.741  1.964   28.664 1.00 32.49  ? 531 GLU F N   1 
ATOM   17278 C CA  . GLU F 1 329 ? 17.294  0.825   27.941 1.00 32.01  ? 531 GLU F CA  1 
ATOM   17279 C C   . GLU F 1 329 ? 16.946  -0.483  28.633 1.00 30.31  ? 531 GLU F C   1 
ATOM   17280 O O   . GLU F 1 329 ? 17.820  -1.183  29.108 1.00 30.29  ? 531 GLU F O   1 
ATOM   17281 C CB  . GLU F 1 329 ? 18.811  0.947   27.833 1.00 28.71  ? 531 GLU F CB  1 
ATOM   17282 C CG  . GLU F 1 329 ? 19.290  2.239   27.202 1.00 32.76  ? 531 GLU F CG  1 
ATOM   17283 C CD  . GLU F 1 329 ? 20.769  2.213   26.878 1.00 36.30  ? 531 GLU F CD  1 
ATOM   17284 O OE1 . GLU F 1 329 ? 21.396  1.143   27.024 1.00 38.47  ? 531 GLU F OE1 1 
ATOM   17285 O OE2 . GLU F 1 329 ? 21.312  3.262   26.476 1.00 37.29  ? 531 GLU F OE2 1 
ATOM   17286 N N   . ASP F 1 330 ? 15.664  -0.821  28.634 1.00 32.93  ? 532 ASP F N   1 
ATOM   17287 C CA  . ASP F 1 330 ? 15.136  -2.036  29.256 1.00 31.28  ? 532 ASP F CA  1 
ATOM   17288 C C   . ASP F 1 330 ? 15.606  -3.359  28.652 1.00 28.09  ? 532 ASP F C   1 
ATOM   17289 O O   . ASP F 1 330 ? 15.790  -4.340  29.365 1.00 27.07  ? 532 ASP F O   1 
ATOM   17290 C CB  . ASP F 1 330 ? 13.607  -2.003  29.267 1.00 32.59  ? 532 ASP F CB  1 
ATOM   17291 C CG  . ASP F 1 330 ? 13.055  -1.001  30.251 1.00 37.69  ? 532 ASP F CG  1 
ATOM   17292 O OD1 . ASP F 1 330 ? 13.801  -0.592  31.161 1.00 40.19  ? 532 ASP F OD1 1 
ATOM   17293 O OD2 . ASP F 1 330 ? 11.872  -0.625  30.118 1.00 40.83  ? 532 ASP F OD2 1 
ATOM   17294 N N   . ARG F 1 331 ? 15.777  -3.387  27.337 1.00 29.37  ? 533 ARG F N   1 
ATOM   17295 C CA  . ARG F 1 331 ? 16.152  -4.609  26.636 1.00 25.75  ? 533 ARG F CA  1 
ATOM   17296 C C   . ARG F 1 331 ? 17.478  -5.221  27.067 1.00 24.40  ? 533 ARG F C   1 
ATOM   17297 O O   . ARG F 1 331 ? 17.608  -6.437  27.116 1.00 23.62  ? 533 ARG F O   1 
ATOM   17298 C CB  . ARG F 1 331 ? 16.139  -4.381  25.125 1.00 26.39  ? 533 ARG F CB  1 
ATOM   17299 C CG  . ARG F 1 331 ? 17.072  -3.292  24.635 1.00 24.22  ? 533 ARG F CG  1 
ATOM   17300 C CD  . ARG F 1 331 ? 16.801  -2.976  23.179 1.00 24.37  ? 533 ARG F CD  1 
ATOM   17301 N NE  . ARG F 1 331 ? 17.932  -2.328  22.530 1.00 24.88  ? 533 ARG F NE  1 
ATOM   17302 C CZ  . ARG F 1 331 ? 18.250  -1.050  22.684 1.00 25.00  ? 533 ARG F CZ  1 
ATOM   17303 N NH1 . ARG F 1 331 ? 19.293  -0.545  22.047 1.00 25.50  ? 533 ARG F NH1 1 
ATOM   17304 N NH2 . ARG F 1 331 ? 17.528  -0.279  23.479 1.00 23.29  ? 533 ARG F NH2 1 
ATOM   17305 N N   . PHE F 1 332 ? 18.465  -4.386  27.356 1.00 24.45  ? 534 PHE F N   1 
ATOM   17306 C CA  . PHE F 1 332 ? 19.774  -4.863  27.769 1.00 21.97  ? 534 PHE F CA  1 
ATOM   17307 C C   . PHE F 1 332 ? 19.818  -5.358  29.207 1.00 20.99  ? 534 PHE F C   1 
ATOM   17308 O O   . PHE F 1 332 ? 19.285  -4.724  30.102 1.00 21.99  ? 534 PHE F O   1 
ATOM   17309 C CB  . PHE F 1 332 ? 20.800  -3.745  27.617 1.00 21.46  ? 534 PHE F CB  1 
ATOM   17310 C CG  . PHE F 1 332 ? 21.003  -3.294  26.207 1.00 21.68  ? 534 PHE F CG  1 
ATOM   17311 C CD1 . PHE F 1 332 ? 21.352  -4.194  25.227 1.00 22.14  ? 534 PHE F CD1 1 
ATOM   17312 C CD2 . PHE F 1 332 ? 20.868  -1.967  25.871 1.00 22.31  ? 534 PHE F CD2 1 
ATOM   17313 C CE1 . PHE F 1 332 ? 21.548  -3.783  23.930 1.00 22.32  ? 534 PHE F CE1 1 
ATOM   17314 C CE2 . PHE F 1 332 ? 21.067  -1.547  24.578 1.00 22.14  ? 534 PHE F CE2 1 
ATOM   17315 C CZ  . PHE F 1 332 ? 21.406  -2.457  23.606 1.00 22.05  ? 534 PHE F CZ  1 
ATOM   17316 N N   . PHE F 1 333 ? 20.464  -6.497  29.418 1.00 21.04  ? 535 PHE F N   1 
ATOM   17317 C CA  . PHE F 1 333 ? 20.646  -7.063  30.742 1.00 19.16  ? 535 PHE F CA  1 
ATOM   17318 C C   . PHE F 1 333 ? 22.097  -7.506  30.883 1.00 18.18  ? 535 PHE F C   1 
ATOM   17319 O O   . PHE F 1 333 ? 22.723  -7.883  29.906 1.00 17.69  ? 535 PHE F O   1 
ATOM   17320 C CB  . PHE F 1 333 ? 19.657  -8.203  31.030 1.00 17.54  ? 535 PHE F CB  1 
ATOM   17321 C CG  . PHE F 1 333 ? 19.856  -9.433  30.188 1.00 17.79  ? 535 PHE F CG  1 
ATOM   17322 C CD1 . PHE F 1 333 ? 20.564  -10.510 30.676 1.00 16.83  ? 535 PHE F CD1 1 
ATOM   17323 C CD2 . PHE F 1 333 ? 19.301  -9.525  28.929 1.00 18.04  ? 535 PHE F CD2 1 
ATOM   17324 C CE1 . PHE F 1 333 ? 20.745  -11.641 29.917 1.00 15.70  ? 535 PHE F CE1 1 
ATOM   17325 C CE2 . PHE F 1 333 ? 19.472  -10.656 28.166 1.00 16.97  ? 535 PHE F CE2 1 
ATOM   17326 C CZ  . PHE F 1 333 ? 20.198  -11.715 28.659 1.00 15.86  ? 535 PHE F CZ  1 
ATOM   17327 N N   . PRO F 1 334 ? 22.657  -7.411  32.093 1.00 19.43  ? 536 PRO F N   1 
ATOM   17328 C CA  . PRO F 1 334 ? 24.036  -7.861  32.312 1.00 19.03  ? 536 PRO F CA  1 
ATOM   17329 C C   . PRO F 1 334 ? 24.115  -9.364  32.084 1.00 18.80  ? 536 PRO F C   1 
ATOM   17330 O O   . PRO F 1 334 ? 23.199  -10.076 32.468 1.00 18.59  ? 536 PRO F O   1 
ATOM   17331 C CB  . PRO F 1 334 ? 24.295  -7.523  33.781 1.00 19.73  ? 536 PRO F CB  1 
ATOM   17332 C CG  . PRO F 1 334 ? 22.974  -7.161  34.364 1.00 19.80  ? 536 PRO F CG  1 
ATOM   17333 C CD  . PRO F 1 334 ? 22.133  -6.661  33.239 1.00 19.72  ? 536 PRO F CD  1 
ATOM   17334 N N   . LEU F 1 335 ? 25.210  -9.860  31.528 1.00 19.87  ? 537 LEU F N   1 
ATOM   17335 C CA  . LEU F 1 335 ? 25.284  -11.278 31.212 1.00 20.27  ? 537 LEU F CA  1 
ATOM   17336 C C   . LEU F 1 335 ? 25.125  -12.203 32.416 1.00 21.23  ? 537 LEU F C   1 
ATOM   17337 O O   . LEU F 1 335 ? 24.389  -13.176 32.342 1.00 21.52  ? 537 LEU F O   1 
ATOM   17338 C CB  . LEU F 1 335 ? 26.604  -11.567 30.500 1.00 20.29  ? 537 LEU F CB  1 
ATOM   17339 C CG  . LEU F 1 335 ? 26.777  -12.885 29.754 1.00 20.19  ? 537 LEU F CG  1 
ATOM   17340 C CD1 . LEU F 1 335 ? 27.972  -12.805 28.827 1.00 20.25  ? 537 LEU F CD1 1 
ATOM   17341 C CD2 . LEU F 1 335 ? 26.938  -14.033 30.728 1.00 21.10  ? 537 LEU F CD2 1 
ATOM   17342 N N   . SER F 1 336 ? 25.800  -11.920 33.520 1.00 21.17  ? 538 SER F N   1 
ATOM   17343 C CA  . SER F 1 336 ? 25.651  -12.753 34.710 1.00 22.59  ? 538 SER F CA  1 
ATOM   17344 C C   . SER F 1 336 ? 25.357  -11.928 35.952 1.00 22.82  ? 538 SER F C   1 
ATOM   17345 O O   . SER F 1 336 ? 25.502  -12.408 37.065 1.00 23.20  ? 538 SER F O   1 
ATOM   17346 C CB  . SER F 1 336 ? 26.874  -13.640 34.926 1.00 24.11  ? 538 SER F CB  1 
ATOM   17347 O OG  . SER F 1 336 ? 28.035  -12.865 35.132 1.00 27.04  ? 538 SER F OG  1 
ATOM   17348 N N   . GLY F 1 337 ? 24.945  -10.685 35.754 1.00 20.84  ? 539 GLY F N   1 
ATOM   17349 C CA  . GLY F 1 337 ? 24.691  -9.774  36.853 1.00 21.98  ? 539 GLY F CA  1 
ATOM   17350 C C   . GLY F 1 337 ? 23.305  -9.737  37.449 1.00 22.57  ? 539 GLY F C   1 
ATOM   17351 O O   . GLY F 1 337 ? 23.055  -8.984  38.378 1.00 24.93  ? 539 GLY F O   1 
ATOM   17352 N N   . SER F 1 338 ? 22.398  -10.546 36.928 1.00 25.84  ? 540 SER F N   1 
ATOM   17353 C CA  . SER F 1 338 ? 21.033  -10.542 37.429 1.00 25.87  ? 540 SER F CA  1 
ATOM   17354 C C   . SER F 1 338 ? 20.558  -11.914 37.852 1.00 24.64  ? 540 SER F C   1 
ATOM   17355 O O   . SER F 1 338 ? 21.077  -12.928 37.400 1.00 24.62  ? 540 SER F O   1 
ATOM   17356 C CB  . SER F 1 338 ? 20.087  -10.025 36.352 1.00 22.68  ? 540 SER F CB  1 
ATOM   17357 O OG  . SER F 1 338 ? 20.449  -8.730  35.936 1.00 24.23  ? 540 SER F OG  1 
ATOM   17358 N N   . LEU F 1 339 ? 19.587  -11.935 38.753 1.00 22.21  ? 541 LEU F N   1 
ATOM   17359 C CA  . LEU F 1 339 ? 18.999  -13.178 39.193 1.00 21.02  ? 541 LEU F CA  1 
ATOM   17360 C C   . LEU F 1 339 ? 17.971  -13.530 38.141 1.00 20.80  ? 541 LEU F C   1 
ATOM   17361 O O   . LEU F 1 339 ? 17.225  -12.672 37.697 1.00 21.29  ? 541 LEU F O   1 
ATOM   17362 C CB  . LEU F 1 339 ? 18.316  -13.006 40.542 1.00 21.17  ? 541 LEU F CB  1 
ATOM   17363 C CG  . LEU F 1 339 ? 19.201  -12.813 41.768 1.00 20.25  ? 541 LEU F CG  1 
ATOM   17364 C CD1 . LEU F 1 339 ? 18.355  -12.918 43.023 1.00 19.78  ? 541 LEU F CD1 1 
ATOM   17365 C CD2 . LEU F 1 339 ? 20.301  -13.856 41.788 1.00 19.63  ? 541 LEU F CD2 1 
ATOM   17366 N N   . ILE F 1 340 ? 17.939  -14.789 37.735 1.00 18.88  ? 542 ILE F N   1 
ATOM   17367 C CA  . ILE F 1 340 ? 16.999  -15.254 36.725 1.00 19.27  ? 542 ILE F CA  1 
ATOM   17368 C C   . ILE F 1 340 ? 16.194  -16.405 37.310 1.00 18.73  ? 542 ILE F C   1 
ATOM   17369 O O   . ILE F 1 340 ? 16.761  -17.427 37.712 1.00 17.73  ? 542 ILE F O   1 
ATOM   17370 C CB  . ILE F 1 340 ? 17.722  -15.680 35.438 1.00 15.98  ? 542 ILE F CB  1 
ATOM   17371 C CG1 . ILE F 1 340 ? 18.501  -14.505 34.860 1.00 18.82  ? 542 ILE F CG1 1 
ATOM   17372 C CG2 . ILE F 1 340 ? 16.728  -16.137 34.408 1.00 17.26  ? 542 ILE F CG2 1 
ATOM   17373 C CD1 . ILE F 1 340 ? 19.419  -14.883 33.736 1.00 20.66  ? 542 ILE F CD1 1 
ATOM   17374 N N   . PHE F 1 341 ? 14.880  -16.233 37.367 1.00 20.07  ? 543 PHE F N   1 
ATOM   17375 C CA  . PHE F 1 341 ? 13.965  -17.226 37.901 1.00 19.94  ? 543 PHE F CA  1 
ATOM   17376 C C   . PHE F 1 341 ? 13.169  -17.853 36.766 1.00 19.35  ? 543 PHE F C   1 
ATOM   17377 O O   . PHE F 1 341 ? 12.865  -17.207 35.762 1.00 18.18  ? 543 PHE F O   1 
ATOM   17378 C CB  . PHE F 1 341 ? 13.005  -16.600 38.917 1.00 15.12  ? 543 PHE F CB  1 
ATOM   17379 C CG  . PHE F 1 341 ? 13.686  -15.981 40.099 1.00 15.61  ? 543 PHE F CG  1 
ATOM   17380 C CD1 . PHE F 1 341 ? 14.066  -16.753 41.178 1.00 15.69  ? 543 PHE F CD1 1 
ATOM   17381 C CD2 . PHE F 1 341 ? 13.925  -14.623 40.139 1.00 15.46  ? 543 PHE F CD2 1 
ATOM   17382 C CE1 . PHE F 1 341 ? 14.686  -16.184 42.267 1.00 15.24  ? 543 PHE F CE1 1 
ATOM   17383 C CE2 . PHE F 1 341 ? 14.544  -14.048 41.225 1.00 15.14  ? 543 PHE F CE2 1 
ATOM   17384 C CZ  . PHE F 1 341 ? 14.923  -14.831 42.292 1.00 15.00  ? 543 PHE F CZ  1 
ATOM   17385 N N   . GLY F 1 342 ? 12.843  -19.127 36.924 1.00 19.94  ? 544 GLY F N   1 
ATOM   17386 C CA  . GLY F 1 342 ? 12.048  -19.857 35.948 1.00 19.99  ? 544 GLY F CA  1 
ATOM   17387 C C   . GLY F 1 342 ? 10.562  -19.671 36.201 1.00 20.19  ? 544 GLY F C   1 
ATOM   17388 O O   . GLY F 1 342 ? 10.129  -19.559 37.349 1.00 20.73  ? 544 GLY F O   1 
ATOM   17389 N N   . LYS F 1 343 ? 9.789   -19.641 35.121 1.00 20.91  ? 545 LYS F N   1 
ATOM   17390 C CA  . LYS F 1 343 ? 8.344   -19.721 35.240 1.00 20.48  ? 545 LYS F CA  1 
ATOM   17391 C C   . LYS F 1 343 ? 7.927   -21.153 35.561 1.00 21.08  ? 545 LYS F C   1 
ATOM   17392 O O   . LYS F 1 343 ? 8.687   -22.105 35.375 1.00 20.21  ? 545 LYS F O   1 
ATOM   17393 C CB  . LYS F 1 343 ? 7.671   -19.241 33.956 1.00 18.26  ? 545 LYS F CB  1 
ATOM   17394 C CG  . LYS F 1 343 ? 7.879   -17.768 33.684 1.00 18.76  ? 545 LYS F CG  1 
ATOM   17395 C CD  . LYS F 1 343 ? 7.272   -17.347 32.368 1.00 19.81  ? 545 LYS F CD  1 
ATOM   17396 C CE  . LYS F 1 343 ? 7.457   -15.859 32.146 1.00 21.72  ? 545 LYS F CE  1 
ATOM   17397 N NZ  . LYS F 1 343 ? 6.911   -15.423 30.835 1.00 22.95  ? 545 LYS F NZ  1 
ATOM   17398 N N   . GLN F 1 344 ? 6.701   -21.322 36.028 1.00 22.85  ? 546 GLN F N   1 
ATOM   17399 C CA  . GLN F 1 344 ? 6.207   -22.649 36.369 1.00 24.03  ? 546 GLN F CA  1 
ATOM   17400 C C   . GLN F 1 344 ? 6.293   -23.622 35.197 1.00 24.06  ? 546 GLN F C   1 
ATOM   17401 O O   . GLN F 1 344 ? 5.861   -23.312 34.089 1.00 23.50  ? 546 GLN F O   1 
ATOM   17402 C CB  . GLN F 1 344 ? 4.762   -22.564 36.859 1.00 20.34  ? 546 GLN F CB  1 
ATOM   17403 C CG  . GLN F 1 344 ? 4.245   -23.853 37.465 1.00 24.74  ? 546 GLN F CG  1 
ATOM   17404 C CD  . GLN F 1 344 ? 5.029   -24.259 38.691 1.00 26.84  ? 546 GLN F CD  1 
ATOM   17405 O OE1 . GLN F 1 344 ? 4.965   -25.402 39.132 1.00 29.20  ? 546 GLN F OE1 1 
ATOM   17406 N NE2 . GLN F 1 344 ? 5.777   -23.319 39.249 1.00 26.75  ? 546 GLN F NE2 1 
ATOM   17407 N N   . GLY F 1 345 ? 6.853   -24.799 35.450 1.00 23.18  ? 547 GLY F N   1 
ATOM   17408 C CA  . GLY F 1 345 ? 6.976   -25.826 34.433 1.00 23.33  ? 547 GLY F CA  1 
ATOM   17409 C C   . GLY F 1 345 ? 8.099   -25.648 33.435 1.00 23.70  ? 547 GLY F C   1 
ATOM   17410 O O   . GLY F 1 345 ? 8.150   -26.346 32.430 1.00 24.29  ? 547 GLY F O   1 
ATOM   17411 N N   . THR F 1 346 ? 8.996   -24.710 33.702 1.00 24.42  ? 548 THR F N   1 
ATOM   17412 C CA  . THR F 1 346 ? 10.117  -24.451 32.807 1.00 24.08  ? 548 THR F CA  1 
ATOM   17413 C C   . THR F 1 346 ? 11.067  -25.643 32.765 1.00 24.94  ? 548 THR F C   1 
ATOM   17414 O O   . THR F 1 346 ? 11.346  -26.251 33.788 1.00 23.41  ? 548 THR F O   1 
ATOM   17415 C CB  . THR F 1 346 ? 10.857  -23.167 33.228 1.00 22.49  ? 548 THR F CB  1 
ATOM   17416 O OG1 . THR F 1 346 ? 9.947   -22.069 33.170 1.00 23.19  ? 548 THR F OG1 1 
ATOM   17417 C CG2 . THR F 1 346 ? 12.019  -22.857 32.310 1.00 21.19  ? 548 THR F CG2 1 
ATOM   17418 N N   . GLY F 1 347 ? 11.551  -25.977 31.573 1.00 24.84  ? 549 GLY F N   1 
ATOM   17419 C CA  . GLY F 1 347 ? 12.475  -27.078 31.397 1.00 26.28  ? 549 GLY F CA  1 
ATOM   17420 C C   . GLY F 1 347 ? 13.824  -26.779 32.009 1.00 27.83  ? 549 GLY F C   1 
ATOM   17421 O O   . GLY F 1 347 ? 14.221  -25.630 32.117 1.00 26.54  ? 549 GLY F O   1 
ATOM   17422 N N   . ARG F 1 348 ? 14.537  -27.821 32.406 1.00 24.11  ? 550 ARG F N   1 
ATOM   17423 C CA  . ARG F 1 348 ? 15.835  -27.657 33.046 1.00 27.00  ? 550 ARG F CA  1 
ATOM   17424 C C   . ARG F 1 348 ? 16.962  -27.163 32.140 1.00 27.55  ? 550 ARG F C   1 
ATOM   17425 O O   . ARG F 1 348 ? 17.825  -26.416 32.583 1.00 27.10  ? 550 ARG F O   1 
ATOM   17426 C CB  . ARG F 1 348 ? 16.253  -28.960 33.723 1.00 25.68  ? 550 ARG F CB  1 
ATOM   17427 C CG  . ARG F 1 348 ? 17.421  -28.802 34.674 1.00 34.03  ? 550 ARG F CG  1 
ATOM   17428 C CD  . ARG F 1 348 ? 17.935  -30.146 35.149 1.00 39.02  ? 550 ARG F CD  1 
ATOM   17429 N NE  . ARG F 1 348 ? 18.919  -29.991 36.212 1.00 43.92  ? 550 ARG F NE  1 
ATOM   17430 C CZ  . ARG F 1 348 ? 20.206  -29.736 36.007 1.00 47.28  ? 550 ARG F CZ  1 
ATOM   17431 N NH1 . ARG F 1 348 ? 21.027  -29.612 37.036 1.00 47.42  ? 550 ARG F NH1 1 
ATOM   17432 N NH2 . ARG F 1 348 ? 20.671  -29.608 34.775 1.00 48.99  ? 550 ARG F NH2 1 
ATOM   17433 N N   . ASP F 1 349 ? 16.965  -27.580 30.880 1.00 26.13  ? 551 ASP F N   1 
ATOM   17434 C CA  . ASP F 1 349 ? 18.030  -27.179 29.956 1.00 27.51  ? 551 ASP F CA  1 
ATOM   17435 C C   . ASP F 1 349 ? 17.621  -26.497 28.646 1.00 26.26  ? 551 ASP F C   1 
ATOM   17436 O O   . ASP F 1 349 ? 16.647  -26.877 28.011 1.00 26.48  ? 551 ASP F O   1 
ATOM   17437 C CB  . ASP F 1 349 ? 18.890  -28.395 29.607 1.00 30.85  ? 551 ASP F CB  1 
ATOM   17438 C CG  . ASP F 1 349 ? 19.417  -29.113 30.832 1.00 36.05  ? 551 ASP F CG  1 
ATOM   17439 O OD1 . ASP F 1 349 ? 20.323  -28.577 31.500 1.00 38.87  ? 551 ASP F OD1 1 
ATOM   17440 O OD2 . ASP F 1 349 ? 18.938  -30.230 31.119 1.00 37.86  ? 551 ASP F OD2 1 
ATOM   17441 N N   . ASN F 1 350 ? 18.396  -25.486 28.264 1.00 24.42  ? 552 ASN F N   1 
ATOM   17442 C CA  . ASN F 1 350 ? 18.226  -24.727 27.019 1.00 22.63  ? 552 ASN F CA  1 
ATOM   17443 C C   . ASN F 1 350 ? 16.863  -24.129 26.695 1.00 20.62  ? 552 ASN F C   1 
ATOM   17444 O O   . ASN F 1 350 ? 16.435  -24.167 25.553 1.00 19.97  ? 552 ASN F O   1 
ATOM   17445 C CB  . ASN F 1 350 ? 18.703  -25.557 25.832 1.00 26.54  ? 552 ASN F CB  1 
ATOM   17446 C CG  . ASN F 1 350 ? 20.195  -25.797 25.859 1.00 27.85  ? 552 ASN F CG  1 
ATOM   17447 O OD1 . ASN F 1 350 ? 20.983  -24.860 25.959 1.00 27.05  ? 552 ASN F OD1 1 
ATOM   17448 N ND2 . ASN F 1 350 ? 20.592  -27.059 25.766 1.00 29.51  ? 552 ASN F ND2 1 
ATOM   17449 N N   . VAL F 1 351 ? 16.200  -23.556 27.688 1.00 22.63  ? 553 VAL F N   1 
ATOM   17450 C CA  . VAL F 1 351 ? 14.899  -22.927 27.488 1.00 21.60  ? 553 VAL F CA  1 
ATOM   17451 C C   . VAL F 1 351 ? 14.999  -21.529 26.876 1.00 22.02  ? 553 VAL F C   1 
ATOM   17452 O O   . VAL F 1 351 ? 16.034  -20.886 26.957 1.00 21.35  ? 553 VAL F O   1 
ATOM   17453 C CB  . VAL F 1 351 ? 14.127  -22.854 28.805 1.00 20.65  ? 553 VAL F CB  1 
ATOM   17454 C CG1 . VAL F 1 351 ? 13.753  -24.251 29.248 1.00 22.74  ? 553 VAL F CG1 1 
ATOM   17455 C CG2 . VAL F 1 351 ? 14.967  -22.172 29.868 1.00 19.28  ? 553 VAL F CG2 1 
ATOM   17456 N N   . ASP F 1 352 ? 13.920  -21.057 26.265 1.00 20.24  ? 554 ASP F N   1 
ATOM   17457 C CA  . ASP F 1 352 ? 13.899  -19.728 25.658 1.00 22.49  ? 554 ASP F CA  1 
ATOM   17458 C C   . ASP F 1 352 ? 13.825  -18.620 26.697 1.00 21.26  ? 554 ASP F C   1 
ATOM   17459 O O   . ASP F 1 352 ? 13.501  -18.861 27.851 1.00 21.68  ? 554 ASP F O   1 
ATOM   17460 C CB  . ASP F 1 352 ? 12.730  -19.604 24.694 1.00 26.31  ? 554 ASP F CB  1 
ATOM   17461 C CG  . ASP F 1 352 ? 12.914  -20.440 23.459 1.00 32.12  ? 554 ASP F CG  1 
ATOM   17462 O OD1 . ASP F 1 352 ? 14.073  -20.722 23.106 1.00 34.67  ? 554 ASP F OD1 1 
ATOM   17463 O OD2 . ASP F 1 352 ? 11.902  -20.813 22.835 1.00 36.07  ? 554 ASP F OD2 1 
ATOM   17464 N N   . ALA F 1 353 ? 14.080  -17.389 26.278 1.00 22.43  ? 555 ALA F N   1 
ATOM   17465 C CA  . ALA F 1 353 ? 14.088  -16.276 27.222 1.00 21.45  ? 555 ALA F CA  1 
ATOM   17466 C C   . ALA F 1 353 ? 12.697  -15.976 27.769 1.00 21.52  ? 555 ALA F C   1 
ATOM   17467 O O   . ALA F 1 353 ? 12.562  -15.291 28.788 1.00 21.02  ? 555 ALA F O   1 
ATOM   17468 C CB  . ALA F 1 353 ? 14.678  -15.031 26.560 1.00 19.51  ? 555 ALA F CB  1 
ATOM   17469 N N   . ASP F 1 354 ? 11.648  -16.477 27.110 1.00 22.14  ? 556 ASP F N   1 
ATOM   17470 C CA  . ASP F 1 354 ? 10.303  -16.281 27.643 1.00 22.69  ? 556 ASP F CA  1 
ATOM   17471 C C   . ASP F 1 354 ? 9.941   -17.347 28.667 1.00 20.72  ? 556 ASP F C   1 
ATOM   17472 O O   . ASP F 1 354 ? 8.855   -17.296 29.253 1.00 19.85  ? 556 ASP F O   1 
ATOM   17473 C CB  . ASP F 1 354 ? 9.276   -16.257 26.513 1.00 24.40  ? 556 ASP F CB  1 
ATOM   17474 C CG  . ASP F 1 354 ? 9.249   -17.544 25.718 1.00 29.67  ? 556 ASP F CG  1 
ATOM   17475 O OD1 . ASP F 1 354 ? 10.115  -18.410 25.945 1.00 33.14  ? 556 ASP F OD1 1 
ATOM   17476 O OD2 . ASP F 1 354 ? 8.354   -17.691 24.860 1.00 32.69  ? 556 ASP F OD2 1 
ATOM   17477 N N   . LYS F 1 355 ? 10.824  -18.319 28.892 1.00 25.21  ? 557 LYS F N   1 
ATOM   17478 C CA  . LYS F 1 355 ? 10.557  -19.327 29.909 1.00 23.11  ? 557 LYS F CA  1 
ATOM   17479 C C   . LYS F 1 355 ? 11.155  -18.930 31.253 1.00 20.62  ? 557 LYS F C   1 
ATOM   17480 O O   . LYS F 1 355 ? 10.890  -19.577 32.272 1.00 18.99  ? 557 LYS F O   1 
ATOM   17481 C CB  . LYS F 1 355 ? 11.107  -20.679 29.461 1.00 21.32  ? 557 LYS F CB  1 
ATOM   17482 C CG  . LYS F 1 355 ? 10.552  -21.170 28.141 1.00 24.35  ? 557 LYS F CG  1 
ATOM   17483 C CD  . LYS F 1 355 ? 9.055   -21.371 28.204 1.00 28.04  ? 557 LYS F CD  1 
ATOM   17484 C CE  . LYS F 1 355 ? 8.531   -21.938 26.898 1.00 32.43  ? 557 LYS F CE  1 
ATOM   17485 N NZ  . LYS F 1 355 ? 7.058   -22.127 26.927 1.00 29.57  ? 557 LYS F NZ  1 
ATOM   17486 N N   . VAL F 1 356 ? 11.960  -17.872 31.279 1.00 19.17  ? 558 VAL F N   1 
ATOM   17487 C CA  . VAL F 1 356 ? 12.653  -17.437 32.485 1.00 18.36  ? 558 VAL F CA  1 
ATOM   17488 C C   . VAL F 1 356 ? 12.248  -16.006 32.804 1.00 18.21  ? 558 VAL F C   1 
ATOM   17489 O O   . VAL F 1 356 ? 11.800  -15.264 31.925 1.00 18.21  ? 558 VAL F O   1 
ATOM   17490 C CB  . VAL F 1 356 ? 14.182  -17.550 32.335 1.00 16.34  ? 558 VAL F CB  1 
ATOM   17491 C CG1 . VAL F 1 356 ? 14.598  -18.998 32.170 1.00 19.89  ? 558 VAL F CG1 1 
ATOM   17492 C CG2 . VAL F 1 356 ? 14.663  -16.714 31.168 1.00 16.36  ? 558 VAL F CG2 1 
ATOM   17493 N N   . MET F 1 357 ? 12.413  -15.624 34.068 1.00 17.51  ? 559 MET F N   1 
ATOM   17494 C CA  . MET F 1 357 ? 12.087  -14.277 34.515 1.00 17.78  ? 559 MET F CA  1 
ATOM   17495 C C   . MET F 1 357 ? 13.353  -13.561 34.965 1.00 17.62  ? 559 MET F C   1 
ATOM   17496 O O   . MET F 1 357 ? 13.931  -13.901 36.000 1.00 17.07  ? 559 MET F O   1 
ATOM   17497 C CB  . MET F 1 357 ? 11.079  -14.337 35.660 1.00 16.72  ? 559 MET F CB  1 
ATOM   17498 C CG  . MET F 1 357 ? 9.755   -14.969 35.273 1.00 20.95  ? 559 MET F CG  1 
ATOM   17499 S SD  . MET F 1 357 ? 8.554   -14.988 36.613 1.00 25.40  ? 559 MET F SD  1 
ATOM   17500 C CE  . MET F 1 357 ? 9.236   -16.249 37.679 1.00 25.10  ? 559 MET F CE  1 
ATOM   17501 N N   . ILE F 1 358 ? 13.824  -12.622 34.155 1.00 18.59  ? 560 ILE F N   1 
ATOM   17502 C CA  . ILE F 1 358 ? 15.048  -11.891 34.453 1.00 18.54  ? 560 ILE F CA  1 
ATOM   17503 C C   . ILE F 1 358 ? 14.795  -10.636 35.264 1.00 20.59  ? 560 ILE F C   1 
ATOM   17504 O O   . ILE F 1 358 ? 14.278  -9.654  34.751 1.00 20.58  ? 560 ILE F O   1 
ATOM   17505 C CB  . ILE F 1 358 ? 15.771  -11.466 33.164 1.00 16.12  ? 560 ILE F CB  1 
ATOM   17506 C CG1 . ILE F 1 358 ? 15.999  -12.664 32.250 1.00 14.65  ? 560 ILE F CG1 1 
ATOM   17507 C CG2 . ILE F 1 358 ? 17.094  -10.798 33.488 1.00 15.11  ? 560 ILE F CG2 1 
ATOM   17508 C CD1 . ILE F 1 358 ? 16.634  -12.295 30.931 1.00 12.81  ? 560 ILE F CD1 1 
ATOM   17509 N N   . THR F 1 359 ? 15.153  -10.672 36.539 1.00 17.31  ? 561 THR F N   1 
ATOM   17510 C CA  . THR F 1 359 ? 14.977  -9.519  37.407 1.00 20.36  ? 561 THR F CA  1 
ATOM   17511 C C   . THR F 1 359 ? 16.016  -8.460  37.086 1.00 23.71  ? 561 THR F C   1 
ATOM   17512 O O   . THR F 1 359 ? 17.071  -8.764  36.555 1.00 23.18  ? 561 THR F O   1 
ATOM   17513 C CB  . THR F 1 359 ? 15.100  -9.895  38.889 1.00 19.04  ? 561 THR F CB  1 
ATOM   17514 O OG1 . THR F 1 359 ? 16.471  -9.845  39.285 1.00 20.56  ? 561 THR F OG1 1 
ATOM   17515 C CG2 . THR F 1 359 ? 14.565  -11.279 39.132 1.00 18.48  ? 561 THR F CG2 1 
ATOM   17516 N N   . ASN F 1 360 ? 15.715  -7.211  37.403 1.00 18.11  ? 562 ASN F N   1 
ATOM   17517 C CA  . ASN F 1 360 ? 16.657  -6.130  37.165 1.00 22.30  ? 562 ASN F CA  1 
ATOM   17518 C C   . ASN F 1 360 ? 16.795  -5.271  38.415 1.00 23.92  ? 562 ASN F C   1 
ATOM   17519 O O   . ASN F 1 360 ? 15.905  -5.233  39.253 1.00 25.18  ? 562 ASN F O   1 
ATOM   17520 C CB  . ASN F 1 360 ? 16.247  -5.296  35.956 1.00 21.49  ? 562 ASN F CB  1 
ATOM   17521 C CG  . ASN F 1 360 ? 14.906  -4.647  36.131 1.00 25.67  ? 562 ASN F CG  1 
ATOM   17522 O OD1 . ASN F 1 360 ? 14.515  -4.311  37.238 1.00 29.99  ? 562 ASN F OD1 1 
ATOM   17523 N ND2 . ASN F 1 360 ? 14.193  -4.465  35.036 1.00 27.79  ? 562 ASN F ND2 1 
ATOM   17524 N N   . GLU F 1 361 ? 17.924  -4.590  38.531 1.00 21.20  ? 563 GLU F N   1 
ATOM   17525 C CA  . GLU F 1 361 ? 18.226  -3.748  39.678 1.00 23.21  ? 563 GLU F CA  1 
ATOM   17526 C C   . GLU F 1 361 ? 18.191  -2.286  39.281 1.00 22.11  ? 563 GLU F C   1 
ATOM   17527 O O   . GLU F 1 361 ? 18.995  -1.496  39.731 1.00 23.75  ? 563 GLU F O   1 
ATOM   17528 C CB  . GLU F 1 361 ? 19.582  -4.107  40.277 1.00 16.76  ? 563 GLU F CB  1 
ATOM   17529 C CG  . GLU F 1 361 ? 19.636  -5.488  40.910 1.00 22.52  ? 563 GLU F CG  1 
ATOM   17530 C CD  . GLU F 1 361 ? 18.774  -5.600  42.153 1.00 25.58  ? 563 GLU F CD  1 
ATOM   17531 O OE1 . GLU F 1 361 ? 18.564  -4.573  42.826 1.00 25.75  ? 563 GLU F OE1 1 
ATOM   17532 O OE2 . GLU F 1 361 ? 18.311  -6.718  42.460 1.00 28.05  ? 563 GLU F OE2 1 
ATOM   17533 N N   . GLU F 1 362 ? 17.233  -1.934  38.443 1.00 24.52  ? 564 GLU F N   1 
ATOM   17534 C CA  . GLU F 1 362 ? 17.092  -0.580  37.932 1.00 23.09  ? 564 GLU F CA  1 
ATOM   17535 C C   . GLU F 1 362 ? 16.894  0.498   39.000 1.00 21.00  ? 564 GLU F C   1 
ATOM   17536 O O   . GLU F 1 362 ? 17.351  1.616   38.832 1.00 20.63  ? 564 GLU F O   1 
ATOM   17537 C CB  . GLU F 1 362 ? 15.971  -0.530  36.897 1.00 28.90  ? 564 GLU F CB  1 
ATOM   17538 C CG  . GLU F 1 362 ? 15.267  0.808   36.803 1.00 33.06  ? 564 GLU F CG  1 
ATOM   17539 C CD  . GLU F 1 362 ? 14.055  0.884   37.706 1.00 35.34  ? 564 GLU F CD  1 
ATOM   17540 O OE1 . GLU F 1 362 ? 13.742  1.987   38.191 1.00 36.08  ? 564 GLU F OE1 1 
ATOM   17541 O OE2 . GLU F 1 362 ? 13.417  -0.161  37.932 1.00 36.50  ? 564 GLU F OE2 1 
ATOM   17542 N N   . GLU F 1 363 ? 16.232  0.173   40.100 1.00 23.45  ? 565 GLU F N   1 
ATOM   17543 C CA  . GLU F 1 363 ? 15.974  1.144   41.166 1.00 21.74  ? 565 GLU F CA  1 
ATOM   17544 C C   . GLU F 1 363 ? 17.216  1.736   41.846 1.00 17.98  ? 565 GLU F C   1 
ATOM   17545 O O   . GLU F 1 363 ? 17.163  2.846   42.356 1.00 17.84  ? 565 GLU F O   1 
ATOM   17546 C CB  . GLU F 1 363 ? 15.055  0.551   42.236 1.00 18.69  ? 565 GLU F CB  1 
ATOM   17547 C CG  . GLU F 1 363 ? 13.929  -0.314  41.701 1.00 26.51  ? 565 GLU F CG  1 
ATOM   17548 C CD  . GLU F 1 363 ? 14.383  -1.720  41.368 1.00 30.72  ? 565 GLU F CD  1 
ATOM   17549 O OE1 . GLU F 1 363 ? 15.290  -2.236  42.056 1.00 30.89  ? 565 GLU F OE1 1 
ATOM   17550 O OE2 . GLU F 1 363 ? 13.830  -2.314  40.421 1.00 33.58  ? 565 GLU F OE2 1 
ATOM   17551 N N   . ILE F 1 364 ? 18.317  0.992   41.872 1.00 21.07  ? 566 ILE F N   1 
ATOM   17552 C CA  . ILE F 1 364 ? 19.545  1.427   42.541 1.00 16.20  ? 566 ILE F CA  1 
ATOM   17553 C C   . ILE F 1 364 ? 20.501  2.281   41.711 1.00 14.90  ? 566 ILE F C   1 
ATOM   17554 O O   . ILE F 1 364 ? 21.603  2.572   42.146 1.00 14.19  ? 566 ILE F O   1 
ATOM   17555 C CB  . ILE F 1 364 ? 20.326  0.255   43.163 1.00 17.65  ? 566 ILE F CB  1 
ATOM   17556 C CG1 . ILE F 1 364 ? 20.991  -0.593  42.085 1.00 16.02  ? 566 ILE F CG1 1 
ATOM   17557 C CG2 . ILE F 1 364 ? 19.418  -0.575  44.046 1.00 17.21  ? 566 ILE F CG2 1 
ATOM   17558 C CD1 . ILE F 1 364 ? 21.564  -1.888  42.604 1.00 14.08  ? 566 ILE F CD1 1 
ATOM   17559 N N   . LYS F 1 365 ? 20.085  2.712   40.529 1.00 17.53  ? 567 LYS F N   1 
ATOM   17560 C CA  . LYS F 1 365 ? 20.939  3.542   39.679 1.00 16.70  ? 567 LYS F CA  1 
ATOM   17561 C C   . LYS F 1 365 ? 21.341  4.891   40.298 1.00 15.72  ? 567 LYS F C   1 
ATOM   17562 O O   . LYS F 1 365 ? 22.369  5.445   39.942 1.00 15.60  ? 567 LYS F O   1 
ATOM   17563 C CB  . LYS F 1 365 ? 20.352  3.714   38.283 1.00 15.35  ? 567 LYS F CB  1 
ATOM   17564 C CG  . LYS F 1 365 ? 18.974  4.328   38.231 1.00 18.23  ? 567 LYS F CG  1 
ATOM   17565 C CD  . LYS F 1 365 ? 18.371  4.083   36.864 1.00 22.90  ? 567 LYS F CD  1 
ATOM   17566 C CE  . LYS F 1 365 ? 16.888  4.386   36.844 1.00 24.39  ? 567 LYS F CE  1 
ATOM   17567 N NZ  . LYS F 1 365 ? 16.252  3.779   35.645 1.00 26.85  ? 567 LYS F NZ  1 
ATOM   17568 N N   . THR F 1 366 ? 20.490  5.459   41.143 1.00 18.32  ? 568 THR F N   1 
ATOM   17569 C CA  . THR F 1 366 ? 20.793  6.698   41.837 1.00 16.69  ? 568 THR F CA  1 
ATOM   17570 C C   . THR F 1 366 ? 22.151  6.676   42.571 1.00 16.41  ? 568 THR F C   1 
ATOM   17571 O O   . THR F 1 366 ? 22.873  7.662   42.521 1.00 15.99  ? 568 THR F O   1 
ATOM   17572 C CB  . THR F 1 366 ? 19.662  7.060   42.805 1.00 15.68  ? 568 THR F CB  1 
ATOM   17573 O OG1 . THR F 1 366 ? 19.497  6.003   43.752 1.00 18.30  ? 568 THR F OG1 1 
ATOM   17574 C CG2 . THR F 1 366 ? 18.368  7.241   42.041 1.00 14.83  ? 568 THR F CG2 1 
ATOM   17575 N N   . THR F 1 367 ? 22.489  5.591   43.273 1.00 15.26  ? 569 THR F N   1 
ATOM   17576 C CA  . THR F 1 367 ? 23.780  5.493   43.938 1.00 15.03  ? 569 THR F CA  1 
ATOM   17577 C C   . THR F 1 367 ? 24.753  4.515   43.295 1.00 14.42  ? 569 THR F C   1 
ATOM   17578 O O   . THR F 1 367 ? 25.908  4.456   43.726 1.00 14.52  ? 569 THR F O   1 
ATOM   17579 C CB  . THR F 1 367 ? 23.598  5.098   45.409 1.00 15.77  ? 569 THR F CB  1 
ATOM   17580 O OG1 . THR F 1 367 ? 22.879  3.864   45.487 1.00 17.22  ? 569 THR F OG1 1 
ATOM   17581 C CG2 . THR F 1 367 ? 22.842  6.165   46.159 1.00 15.82  ? 569 THR F CG2 1 
ATOM   17582 N N   . ASN F 1 368 ? 24.344  3.763   42.277 1.00 13.75  ? 570 ASN F N   1 
ATOM   17583 C CA  . ASN F 1 368 ? 25.249  2.739   41.779 1.00 13.71  ? 570 ASN F CA  1 
ATOM   17584 C C   . ASN F 1 368 ? 25.465  2.876   40.280 1.00 14.67  ? 570 ASN F C   1 
ATOM   17585 O O   . ASN F 1 368 ? 24.536  3.204   39.539 1.00 16.10  ? 570 ASN F O   1 
ATOM   17586 C CB  . ASN F 1 368 ? 24.730  1.329   42.079 1.00 13.06  ? 570 ASN F CB  1 
ATOM   17587 C CG  . ASN F 1 368 ? 24.809  0.988   43.541 1.00 13.77  ? 570 ASN F CG  1 
ATOM   17588 O OD1 . ASN F 1 368 ? 25.568  1.599   44.279 1.00 14.36  ? 570 ASN F OD1 1 
ATOM   17589 N ND2 . ASN F 1 368 ? 24.040  0.003   43.967 1.00 14.48  ? 570 ASN F ND2 1 
ATOM   17590 N N   . PRO F 1 369 ? 26.677  2.617   39.806 1.00 13.78  ? 571 PRO F N   1 
ATOM   17591 C CA  . PRO F 1 369 ? 26.938  2.701   38.370 1.00 13.88  ? 571 PRO F CA  1 
ATOM   17592 C C   . PRO F 1 369 ? 26.266  1.565   37.621 1.00 14.23  ? 571 PRO F C   1 
ATOM   17593 O O   . PRO F 1 369 ? 25.940  0.517   38.179 1.00 14.34  ? 571 PRO F O   1 
ATOM   17594 C CB  . PRO F 1 369 ? 28.461  2.598   38.284 1.00 13.55  ? 571 PRO F CB  1 
ATOM   17595 C CG  . PRO F 1 369 ? 28.831  1.799   39.474 1.00 13.50  ? 571 PRO F CG  1 
ATOM   17596 C CD  . PRO F 1 369 ? 27.874  2.206   40.557 1.00 13.14  ? 571 PRO F CD  1 
ATOM   17597 N N   . VAL F 1 370 ? 26.057  1.794   36.327 1.00 16.44  ? 572 VAL F N   1 
ATOM   17598 C CA  . VAL F 1 370 ? 25.477  0.771   35.469 1.00 15.82  ? 572 VAL F CA  1 
ATOM   17599 C C   . VAL F 1 370 ? 26.461  -0.381  35.320 1.00 16.24  ? 572 VAL F C   1 
ATOM   17600 O O   . VAL F 1 370 ? 27.679  -0.177  35.238 1.00 16.03  ? 572 VAL F O   1 
ATOM   17601 C CB  . VAL F 1 370 ? 25.098  1.377   34.109 1.00 16.21  ? 572 VAL F CB  1 
ATOM   17602 C CG1 . VAL F 1 370 ? 24.585  0.310   33.171 1.00 15.91  ? 572 VAL F CG1 1 
ATOM   17603 C CG2 . VAL F 1 370 ? 24.061  2.462   34.298 1.00 15.80  ? 572 VAL F CG2 1 
ATOM   17604 N N   . ALA F 1 371 ? 25.933  -1.606  35.297 1.00 16.93  ? 573 ALA F N   1 
ATOM   17605 C CA  . ALA F 1 371 ? 26.791  -2.785  35.303 1.00 17.00  ? 573 ALA F CA  1 
ATOM   17606 C C   . ALA F 1 371 ? 27.531  -2.965  33.986 1.00 17.60  ? 573 ALA F C   1 
ATOM   17607 O O   . ALA F 1 371 ? 28.613  -3.558  33.964 1.00 16.96  ? 573 ALA F O   1 
ATOM   17608 C CB  . ALA F 1 371 ? 25.964  -4.028  35.614 1.00 16.15  ? 573 ALA F CB  1 
ATOM   17609 N N   . THR F 1 372 ? 26.964  -2.482  32.885 1.00 18.51  ? 574 THR F N   1 
ATOM   17610 C CA  . THR F 1 372 ? 27.553  -2.632  31.563 1.00 19.00  ? 574 THR F CA  1 
ATOM   17611 C C   . THR F 1 372 ? 28.372  -1.422  31.132 1.00 19.89  ? 574 THR F C   1 
ATOM   17612 O O   . THR F 1 372 ? 28.817  -1.366  29.983 1.00 21.09  ? 574 THR F O   1 
ATOM   17613 C CB  . THR F 1 372 ? 26.461  -2.925  30.540 1.00 20.36  ? 574 THR F CB  1 
ATOM   17614 O OG1 . THR F 1 372 ? 25.506  -1.858  30.537 1.00 20.37  ? 574 THR F OG1 1 
ATOM   17615 C CG2 . THR F 1 372 ? 25.759  -4.219  30.898 1.00 19.83  ? 574 THR F CG2 1 
ATOM   17616 N N   . GLU F 1 373 ? 28.569  -0.452  32.015 1.00 19.28  ? 575 GLU F N   1 
ATOM   17617 C CA  . GLU F 1 373 ? 29.289  0.773   31.711 1.00 20.81  ? 575 GLU F CA  1 
ATOM   17618 C C   . GLU F 1 373 ? 30.568  0.837   32.533 1.00 19.37  ? 575 GLU F C   1 
ATOM   17619 O O   . GLU F 1 373 ? 30.702  0.176   33.565 1.00 19.07  ? 575 GLU F O   1 
ATOM   17620 C CB  . GLU F 1 373 ? 28.435  2.006   32.020 1.00 16.87  ? 575 GLU F CB  1 
ATOM   17621 C CG  . GLU F 1 373 ? 27.163  2.150   31.210 1.00 23.87  ? 575 GLU F CG  1 
ATOM   17622 C CD  . GLU F 1 373 ? 27.412  2.263   29.725 1.00 28.22  ? 575 GLU F CD  1 
ATOM   17623 O OE1 . GLU F 1 373 ? 28.428  2.873   29.334 1.00 30.76  ? 575 GLU F OE1 1 
ATOM   17624 O OE2 . GLU F 1 373 ? 26.574  1.764   28.949 1.00 30.87  ? 575 GLU F OE2 1 
ATOM   17625 N N   . SER F 1 374 ? 31.517  1.637   32.057 1.00 20.64  ? 576 SER F N   1 
ATOM   17626 C CA  . SER F 1 374 ? 32.727  1.882   32.826 1.00 20.54  ? 576 SER F CA  1 
ATOM   17627 C C   . SER F 1 374 ? 32.411  2.711   34.062 1.00 19.90  ? 576 SER F C   1 
ATOM   17628 O O   . SER F 1 374 ? 31.393  3.402   34.131 1.00 20.72  ? 576 SER F O   1 
ATOM   17629 C CB  . SER F 1 374 ? 33.771  2.601   31.978 1.00 20.58  ? 576 SER F CB  1 
ATOM   17630 O OG  . SER F 1 374 ? 34.214  1.777   30.919 1.00 23.98  ? 576 SER F OG  1 
ATOM   17631 N N   . TYR F 1 375 ? 33.299  2.631   35.052 1.00 21.38  ? 577 TYR F N   1 
ATOM   17632 C CA  . TYR F 1 375 ? 33.141  3.469   36.233 1.00 20.13  ? 577 TYR F CA  1 
ATOM   17633 C C   . TYR F 1 375 ? 33.377  4.931   35.890 1.00 20.54  ? 577 TYR F C   1 
ATOM   17634 O O   . TYR F 1 375 ? 32.619  5.808   36.318 1.00 20.19  ? 577 TYR F O   1 
ATOM   17635 C CB  . TYR F 1 375 ? 34.099  3.022   37.335 1.00 20.77  ? 577 TYR F CB  1 
ATOM   17636 C CG  . TYR F 1 375 ? 34.000  3.870   38.578 1.00 19.97  ? 577 TYR F CG  1 
ATOM   17637 C CD1 . TYR F 1 375 ? 33.008  3.642   39.516 1.00 20.04  ? 577 TYR F CD1 1 
ATOM   17638 C CD2 . TYR F 1 375 ? 34.872  4.923   38.797 1.00 19.00  ? 577 TYR F CD2 1 
ATOM   17639 C CE1 . TYR F 1 375 ? 32.903  4.418   40.644 1.00 19.93  ? 577 TYR F CE1 1 
ATOM   17640 C CE2 . TYR F 1 375 ? 34.770  5.708   39.922 1.00 18.44  ? 577 TYR F CE2 1 
ATOM   17641 C CZ  . TYR F 1 375 ? 33.783  5.449   40.842 1.00 18.99  ? 577 TYR F CZ  1 
ATOM   17642 O OH  . TYR F 1 375 ? 33.671  6.224   41.970 1.00 19.25  ? 577 TYR F OH  1 
ATOM   17643 N N   . GLY F 1 376 ? 34.408  5.208   35.101 1.00 24.69  ? 578 GLY F N   1 
ATOM   17644 C CA  . GLY F 1 376 ? 34.778  6.576   34.797 1.00 24.31  ? 578 GLY F CA  1 
ATOM   17645 C C   . GLY F 1 376 ? 36.059  6.605   33.989 1.00 24.80  ? 578 GLY F C   1 
ATOM   17646 O O   . GLY F 1 376 ? 36.404  5.629   33.321 1.00 24.59  ? 578 GLY F O   1 
ATOM   17647 N N   . GLN F 1 377 ? 36.749  7.743   34.049 1.00 27.82  ? 579 GLN F N   1 
ATOM   17648 C CA  . GLN F 1 377 ? 38.010  7.924   33.346 1.00 28.92  ? 579 GLN F CA  1 
ATOM   17649 C C   . GLN F 1 377 ? 39.078  8.449   34.294 1.00 28.03  ? 579 GLN F C   1 
ATOM   17650 O O   . GLN F 1 377 ? 38.783  9.141   35.271 1.00 27.95  ? 579 GLN F O   1 
ATOM   17651 C CB  . GLN F 1 377 ? 37.871  8.880   32.168 1.00 25.53  ? 579 GLN F CB  1 
ATOM   17652 C CG  . GLN F 1 377 ? 37.008  8.355   31.049 1.00 31.86  ? 579 GLN F CG  1 
ATOM   17653 C CD  . GLN F 1 377 ? 36.886  9.342   29.912 1.00 37.15  ? 579 GLN F CD  1 
ATOM   17654 O OE1 . GLN F 1 377 ? 37.053  10.545  30.101 1.00 40.34  ? 579 GLN F OE1 1 
ATOM   17655 N NE2 . GLN F 1 377 ? 36.597  8.839   28.721 1.00 38.61  ? 579 GLN F NE2 1 
ATOM   17656 N N   . VAL F 1 378 ? 40.330  8.112   33.985 1.00 31.54  ? 580 VAL F N   1 
ATOM   17657 C CA  . VAL F 1 378 ? 41.493  8.574   34.728 1.00 31.44  ? 580 VAL F CA  1 
ATOM   17658 C C   . VAL F 1 378 ? 42.496  9.158   33.745 1.00 32.19  ? 580 VAL F C   1 
ATOM   17659 O O   . VAL F 1 378 ? 42.397  8.966   32.534 1.00 31.92  ? 580 VAL F O   1 
ATOM   17660 C CB  . VAL F 1 378 ? 42.153  7.449   35.555 1.00 29.21  ? 580 VAL F CB  1 
ATOM   17661 C CG1 . VAL F 1 378 ? 41.230  6.983   36.647 1.00 29.64  ? 580 VAL F CG1 1 
ATOM   17662 C CG2 . VAL F 1 378 ? 42.531  6.287   34.657 1.00 28.15  ? 580 VAL F CG2 1 
ATOM   17663 N N   . ALA F 1 379 ? 43.471  9.883   34.283 1.00 37.07  ? 581 ALA F N   1 
ATOM   17664 C CA  . ALA F 1 379 ? 44.571  10.388  33.476 1.00 38.51  ? 581 ALA F CA  1 
ATOM   17665 C C   . ALA F 1 379 ? 45.622  9.300   33.302 1.00 39.52  ? 581 ALA F C   1 
ATOM   17666 O O   . ALA F 1 379 ? 46.036  8.666   34.276 1.00 39.16  ? 581 ALA F O   1 
ATOM   17667 C CB  . ALA F 1 379 ? 45.188  11.622  34.129 1.00 38.14  ? 581 ALA F CB  1 
ATOM   17668 N N   . THR F 1 380 ? 46.025  9.051   32.058 1.00 41.93  ? 582 THR F N   1 
ATOM   17669 C CA  . THR F 1 380 ? 46.998  8.009   31.764 1.00 42.59  ? 582 THR F CA  1 
ATOM   17670 C C   . THR F 1 380 ? 48.419  8.519   31.546 1.00 43.85  ? 582 THR F C   1 
ATOM   17671 O O   . THR F 1 380 ? 49.323  7.702   31.353 1.00 44.49  ? 582 THR F O   1 
ATOM   17672 C CB  . THR F 1 380 ? 46.556  7.206   30.538 1.00 44.03  ? 582 THR F CB  1 
ATOM   17673 O OG1 . THR F 1 380 ? 46.387  8.085   29.422 1.00 45.69  ? 582 THR F OG1 1 
ATOM   17674 C CG2 . THR F 1 380 ? 45.253  6.487   30.819 1.00 41.87  ? 582 THR F CG2 1 
ATOM   17675 N N   . ASN F 1 381 ? 48.629  9.829   31.544 1.00 45.33  ? 583 ASN F N   1 
ATOM   17676 C CA  . ASN F 1 381 ? 49.960  10.371  31.304 1.00 46.21  ? 583 ASN F CA  1 
ATOM   17677 C C   . ASN F 1 381 ? 50.084  11.787  31.826 1.00 47.48  ? 583 ASN F C   1 
ATOM   17678 O O   . ASN F 1 381 ? 49.173  12.293  32.476 1.00 47.72  ? 583 ASN F O   1 
ATOM   17679 C CB  . ASN F 1 381 ? 50.256  10.365  29.803 1.00 49.30  ? 583 ASN F CB  1 
ATOM   17680 C CG  . ASN F 1 381 ? 49.455  11.407  29.039 1.00 49.58  ? 583 ASN F CG  1 
ATOM   17681 O OD1 . ASN F 1 381 ? 48.432  11.887  29.513 1.00 51.02  ? 583 ASN F OD1 1 
ATOM   17682 N ND2 . ASN F 1 381 ? 49.936  11.777  27.861 1.00 49.81  ? 583 ASN F ND2 1 
ATOM   17683 N N   . HIS F 1 382 ? 51.218  12.424  31.556 1.00 50.65  ? 584 HIS F N   1 
ATOM   17684 C CA  . HIS F 1 382 ? 51.407  13.803  31.956 1.00 51.29  ? 584 HIS F CA  1 
ATOM   17685 C C   . HIS F 1 382 ? 51.301  14.658  30.710 1.00 50.93  ? 584 HIS F C   1 
ATOM   17686 O O   . HIS F 1 382 ? 52.026  14.445  29.746 1.00 51.13  ? 584 HIS F O   1 
ATOM   17687 C CB  . HIS F 1 382 ? 52.786  14.015  32.567 1.00 48.60  ? 584 HIS F CB  1 
ATOM   17688 C CG  . HIS F 1 382 ? 52.895  13.583  33.991 1.00 51.96  ? 584 HIS F CG  1 
ATOM   17689 N ND1 . HIS F 1 382 ? 53.803  12.638  34.410 1.00 53.50  ? 584 HIS F ND1 1 
ATOM   17690 C CD2 . HIS F 1 382 ? 52.217  13.968  35.095 1.00 54.18  ? 584 HIS F CD2 1 
ATOM   17691 C CE1 . HIS F 1 382 ? 53.678  12.456  35.711 1.00 54.73  ? 584 HIS F CE1 1 
ATOM   17692 N NE2 . HIS F 1 382 ? 52.722  13.252  36.151 1.00 56.10  ? 584 HIS F NE2 1 
ATOM   17693 N N   . GLN F 1 383 ? 50.393  15.626  30.725 1.00 56.84  ? 585 GLN F N   1 
ATOM   17694 C CA  . GLN F 1 383 ? 50.241  16.532  29.599 1.00 56.00  ? 585 GLN F CA  1 
ATOM   17695 C C   . GLN F 1 383 ? 51.487  17.408  29.542 1.00 56.28  ? 585 GLN F C   1 
ATOM   17696 O O   . GLN F 1 383 ? 52.047  17.781  30.572 1.00 56.06  ? 585 GLN F O   1 
ATOM   17697 C CB  . GLN F 1 383 ? 49.016  17.411  29.778 1.00 53.53  ? 585 GLN F CB  1 
ATOM   17698 C CG  . GLN F 1 383 ? 49.081  18.222  31.051 1.00 51.75  ? 585 GLN F CG  1 
ATOM   17699 C CD  . GLN F 1 383 ? 48.853  19.692  30.809 1.00 50.59  ? 585 GLN F CD  1 
ATOM   17700 O OE1 . GLN F 1 383 ? 47.842  20.088  30.236 1.00 50.36  ? 585 GLN F OE1 1 
ATOM   17701 N NE2 . GLN F 1 383 ? 49.795  20.514  31.252 1.00 50.00  ? 585 GLN F NE2 1 
ATOM   17702 N N   . SER F 1 384 ? 51.909  17.754  28.337 1.00 55.70  ? 586 SER F N   1 
ATOM   17703 C CA  . SER F 1 384 ? 53.106  18.555  28.152 1.00 56.30  ? 586 SER F CA  1 
ATOM   17704 C C   . SER F 1 384 ? 53.017  19.294  26.836 1.00 56.79  ? 586 SER F C   1 
ATOM   17705 O O   . SER F 1 384 ? 52.030  19.188  26.127 1.00 56.17  ? 586 SER F O   1 
ATOM   17706 C CB  . SER F 1 384 ? 54.350  17.672  28.169 1.00 57.48  ? 586 SER F CB  1 
ATOM   17707 O OG  . SER F 1 384 ? 54.509  16.989  26.939 1.00 56.95  ? 586 SER F OG  1 
ATOM   17708 N N   . ALA F 1 385 ? 54.037  20.076  26.509 1.00 55.83  ? 587 ALA F N   1 
ATOM   17709 C CA  . ALA F 1 385 ? 54.031  20.791  25.241 1.00 57.01  ? 587 ALA F CA  1 
ATOM   17710 C C   . ALA F 1 385 ? 53.995  19.809  24.067 1.00 58.45  ? 587 ALA F C   1 
ATOM   17711 O O   . ALA F 1 385 ? 53.299  20.045  23.084 1.00 58.53  ? 587 ALA F O   1 
ATOM   17712 C CB  . ALA F 1 385 ? 55.237  21.709  25.139 1.00 56.12  ? 587 ALA F CB  1 
ATOM   17713 N N   . GLN F 1 386 ? 54.747  18.716  24.167 1.00 57.21  ? 588 GLN F N   1 
ATOM   17714 C CA  . GLN F 1 386 ? 54.782  17.696  23.127 1.00 59.31  ? 588 GLN F CA  1 
ATOM   17715 C C   . GLN F 1 386 ? 53.767  16.557  23.297 1.00 59.30  ? 588 GLN F C   1 
ATOM   17716 O O   . GLN F 1 386 ? 53.698  15.675  22.446 1.00 60.47  ? 588 GLN F O   1 
ATOM   17717 C CB  . GLN F 1 386 ? 56.187  17.101  23.021 1.00 63.58  ? 588 GLN F CB  1 
ATOM   17718 C CG  . GLN F 1 386 ? 57.272  18.097  22.647 1.00 63.58  ? 588 GLN F CG  1 
ATOM   17719 C CD  . GLN F 1 386 ? 57.684  18.980  23.808 1.00 63.58  ? 588 GLN F CD  1 
ATOM   17720 O OE1 . GLN F 1 386 ? 57.300  18.740  24.951 1.00 63.58  ? 588 GLN F OE1 1 
ATOM   17721 N NE2 . GLN F 1 386 ? 58.473  20.006  23.519 1.00 63.58  ? 588 GLN F NE2 1 
ATOM   17722 N N   . ALA F 1 387 ? 52.985  16.559  24.375 1.00 55.93  ? 589 ALA F N   1 
ATOM   17723 C CA  . ALA F 1 387 ? 52.019  15.469  24.602 1.00 54.08  ? 589 ALA F CA  1 
ATOM   17724 C C   . ALA F 1 387 ? 50.617  15.883  25.049 1.00 53.05  ? 589 ALA F C   1 
ATOM   17725 O O   . ALA F 1 387 ? 50.456  16.598  26.026 1.00 53.46  ? 589 ALA F O   1 
ATOM   17726 C CB  . ALA F 1 387 ? 52.593  14.460  25.585 1.00 55.12  ? 589 ALA F CB  1 
ATOM   17727 N N   . GLN F 1 388 ? 49.599  15.388  24.353 1.00 54.17  ? 590 GLN F N   1 
ATOM   17728 C CA  . GLN F 1 388 ? 48.224  15.712  24.694 1.00 54.10  ? 590 GLN F CA  1 
ATOM   17729 C C   . GLN F 1 388 ? 47.794  14.961  25.948 1.00 53.02  ? 590 GLN F C   1 
ATOM   17730 O O   . GLN F 1 388 ? 48.303  13.885  26.269 1.00 52.48  ? 590 GLN F O   1 
ATOM   17731 C CB  . GLN F 1 388 ? 47.285  15.364  23.542 1.00 54.04  ? 590 GLN F CB  1 
ATOM   17732 C CG  . GLN F 1 388 ? 47.505  16.175  22.287 1.00 54.04  ? 590 GLN F CG  1 
ATOM   17733 C CD  . GLN F 1 388 ? 46.566  15.769  21.174 1.00 54.04  ? 590 GLN F CD  1 
ATOM   17734 O OE1 . GLN F 1 388 ? 46.060  14.648  21.154 1.00 54.04  ? 590 GLN F OE1 1 
ATOM   17735 N NE2 . GLN F 1 388 ? 46.324  16.680  20.241 1.00 54.04  ? 590 GLN F NE2 1 
ATOM   17736 N N   . ALA F 1 389 ? 46.832  15.540  26.658 1.00 51.37  ? 591 ALA F N   1 
ATOM   17737 C CA  . ALA F 1 389 ? 46.302  14.880  27.839 1.00 51.13  ? 591 ALA F CA  1 
ATOM   17738 C C   . ALA F 1 389 ? 45.504  13.652  27.430 1.00 50.95  ? 591 ALA F C   1 
ATOM   17739 O O   . ALA F 1 389 ? 44.530  13.745  26.678 1.00 50.60  ? 591 ALA F O   1 
ATOM   17740 C CB  . ALA F 1 389 ? 45.425  15.840  28.639 1.00 46.60  ? 591 ALA F CB  1 
ATOM   17741 N N   . GLN F 1 390 ? 45.914  12.496  27.940 1.00 46.00  ? 592 GLN F N   1 
ATOM   17742 C CA  . GLN F 1 390 ? 45.305  11.228  27.576 1.00 46.50  ? 592 GLN F CA  1 
ATOM   17743 C C   . GLN F 1 390 ? 44.547  10.674  28.767 1.00 46.30  ? 592 GLN F C   1 
ATOM   17744 O O   . GLN F 1 390 ? 44.912  10.925  29.919 1.00 45.72  ? 592 GLN F O   1 
ATOM   17745 C CB  . GLN F 1 390 ? 46.348  10.216  27.114 1.00 54.97  ? 592 GLN F CB  1 
ATOM   17746 C CG  . GLN F 1 390 ? 47.057  10.593  25.837 1.00 54.97  ? 592 GLN F CG  1 
ATOM   17747 C CD  . GLN F 1 390 ? 48.106  9.579   25.447 1.00 54.97  ? 592 GLN F CD  1 
ATOM   17748 O OE1 . GLN F 1 390 ? 48.603  8.830   26.287 1.00 54.97  ? 592 GLN F OE1 1 
ATOM   17749 N NE2 . GLN F 1 390 ? 48.456  9.553   24.168 1.00 54.97  ? 592 GLN F NE2 1 
ATOM   17750 N N   . THR F 1 391 ? 43.490  9.921   28.484 1.00 40.32  ? 593 THR F N   1 
ATOM   17751 C CA  . THR F 1 391 ? 42.660  9.313   29.509 1.00 40.60  ? 593 THR F CA  1 
ATOM   17752 C C   . THR F 1 391 ? 42.454  7.841   29.189 1.00 39.07  ? 593 THR F C   1 
ATOM   17753 O O   . THR F 1 391 ? 42.759  7.368   28.092 1.00 39.18  ? 593 THR F O   1 
ATOM   17754 C CB  . THR F 1 391 ? 41.301  10.020  29.637 1.00 39.36  ? 593 THR F CB  1 
ATOM   17755 O OG1 . THR F 1 391 ? 40.618  9.989   28.379 1.00 41.80  ? 593 THR F OG1 1 
ATOM   17756 C CG2 . THR F 1 391 ? 41.484  11.458  30.082 1.00 38.86  ? 593 THR F CG2 1 
ATOM   17757 N N   . GLY F 1 392 ? 41.923  7.115   30.166 1.00 31.83  ? 594 GLY F N   1 
ATOM   17758 C CA  . GLY F 1 392 ? 41.634  5.708   29.974 1.00 29.91  ? 594 GLY F CA  1 
ATOM   17759 C C   . GLY F 1 392 ? 40.432  5.301   30.793 1.00 28.87  ? 594 GLY F C   1 
ATOM   17760 O O   . GLY F 1 392 ? 40.086  5.938   31.792 1.00 28.96  ? 594 GLY F O   1 
ATOM   17761 N N   . TRP F 1 393 ? 39.804  4.214   30.362 1.00 27.10  ? 595 TRP F N   1 
ATOM   17762 C CA  . TRP F 1 393 ? 38.555  3.764   30.953 1.00 26.42  ? 595 TRP F CA  1 
ATOM   17763 C C   . TRP F 1 393 ? 38.821  2.876   32.156 1.00 24.70  ? 595 TRP F C   1 
ATOM   17764 O O   . TRP F 1 393 ? 39.698  2.009   32.125 1.00 24.67  ? 595 TRP F O   1 
ATOM   17765 C CB  . TRP F 1 393 ? 37.718  3.001   29.929 1.00 21.65  ? 595 TRP F CB  1 
ATOM   17766 C CG  . TRP F 1 393 ? 37.255  3.842   28.802 1.00 25.45  ? 595 TRP F CG  1 
ATOM   17767 C CD1 . TRP F 1 393 ? 37.815  3.928   27.567 1.00 26.14  ? 595 TRP F CD1 1 
ATOM   17768 C CD2 . TRP F 1 393 ? 36.149  4.745   28.807 1.00 27.79  ? 595 TRP F CD2 1 
ATOM   17769 N NE1 . TRP F 1 393 ? 37.116  4.819   26.792 1.00 27.61  ? 595 TRP F NE1 1 
ATOM   17770 C CE2 . TRP F 1 393 ? 36.088  5.337   27.534 1.00 28.13  ? 595 TRP F CE2 1 
ATOM   17771 C CE3 . TRP F 1 393 ? 35.200  5.107   29.765 1.00 29.79  ? 595 TRP F CE3 1 
ATOM   17772 C CZ2 . TRP F 1 393 ? 35.117  6.270   27.191 1.00 28.90  ? 595 TRP F CZ2 1 
ATOM   17773 C CZ3 . TRP F 1 393 ? 34.237  6.031   29.424 1.00 31.22  ? 595 TRP F CZ3 1 
ATOM   17774 C CH2 . TRP F 1 393 ? 34.201  6.603   28.148 1.00 30.54  ? 595 TRP F CH2 1 
ATOM   17775 N N   . VAL F 1 394 ? 38.050  3.091   33.215 1.00 23.76  ? 596 VAL F N   1 
ATOM   17776 C CA  . VAL F 1 394 ? 38.118  2.256   34.405 1.00 22.13  ? 596 VAL F CA  1 
ATOM   17777 C C   . VAL F 1 394 ? 37.064  1.170   34.256 1.00 22.29  ? 596 VAL F C   1 
ATOM   17778 O O   . VAL F 1 394 ? 35.864  1.442   34.333 1.00 21.77  ? 596 VAL F O   1 
ATOM   17779 C CB  . VAL F 1 394 ? 37.895  3.073   35.680 1.00 23.36  ? 596 VAL F CB  1 
ATOM   17780 C CG1 . VAL F 1 394 ? 37.798  2.152   36.874 1.00 21.91  ? 596 VAL F CG1 1 
ATOM   17781 C CG2 . VAL F 1 394 ? 39.014  4.067   35.865 1.00 21.29  ? 596 VAL F CG2 1 
ATOM   17782 N N   . GLN F 1 395 ? 37.507  -0.065  34.040 1.00 20.48  ? 597 GLN F N   1 
ATOM   17783 C CA  . GLN F 1 395 ? 36.546  -1.141  33.860 1.00 21.22  ? 597 GLN F CA  1 
ATOM   17784 C C   . GLN F 1 395 ? 36.046  -1.676  35.193 1.00 21.55  ? 597 GLN F C   1 
ATOM   17785 O O   . GLN F 1 395 ? 34.867  -2.018  35.318 1.00 22.47  ? 597 GLN F O   1 
ATOM   17786 C CB  . GLN F 1 395 ? 37.156  -2.265  33.031 1.00 21.66  ? 597 GLN F CB  1 
ATOM   17787 C CG  . GLN F 1 395 ? 37.668  -1.832  31.670 1.00 23.01  ? 597 GLN F CG  1 
ATOM   17788 C CD  . GLN F 1 395 ? 36.652  -1.057  30.856 1.00 21.83  ? 597 GLN F CD  1 
ATOM   17789 O OE1 . GLN F 1 395 ? 35.456  -1.305  30.930 1.00 23.26  ? 597 GLN F OE1 1 
ATOM   17790 N NE2 . GLN F 1 395 ? 37.134  -0.122  30.054 1.00 21.38  ? 597 GLN F NE2 1 
ATOM   17791 N N   . ASN F 1 396 ? 36.919  -1.746  36.191 1.00 22.11  ? 598 ASN F N   1 
ATOM   17792 C CA  . ASN F 1 396 ? 36.538  -2.142  37.535 1.00 21.94  ? 598 ASN F CA  1 
ATOM   17793 C C   . ASN F 1 396 ? 37.142  -1.169  38.532 1.00 21.56  ? 598 ASN F C   1 
ATOM   17794 O O   . ASN F 1 396 ? 38.290  -0.742  38.382 1.00 22.76  ? 598 ASN F O   1 
ATOM   17795 C CB  . ASN F 1 396 ? 36.988  -3.569  37.846 1.00 23.14  ? 598 ASN F CB  1 
ATOM   17796 C CG  . ASN F 1 396 ? 38.476  -3.752  37.703 1.00 24.11  ? 598 ASN F CG  1 
ATOM   17797 O OD1 . ASN F 1 396 ? 39.156  -2.957  37.062 1.00 24.91  ? 598 ASN F OD1 1 
ATOM   17798 N ND2 . ASN F 1 396 ? 38.994  -4.803  38.310 1.00 23.68  ? 598 ASN F ND2 1 
ATOM   17799 N N   . GLN F 1 397 ? 36.361  -0.814  39.546 1.00 23.91  ? 599 GLN F N   1 
ATOM   17800 C CA  . GLN F 1 397 ? 36.802  0.126   40.566 1.00 21.99  ? 599 GLN F CA  1 
ATOM   17801 C C   . GLN F 1 397 ? 36.497  -0.462  41.930 1.00 21.94  ? 599 GLN F C   1 
ATOM   17802 O O   . GLN F 1 397 ? 35.334  -0.719  42.250 1.00 22.48  ? 599 GLN F O   1 
ATOM   17803 C CB  . GLN F 1 397 ? 36.117  1.486   40.402 1.00 25.42  ? 599 GLN F CB  1 
ATOM   17804 C CG  . GLN F 1 397 ? 36.583  2.546   41.389 1.00 24.84  ? 599 GLN F CG  1 
ATOM   17805 C CD  . GLN F 1 397 ? 38.048  2.879   41.239 1.00 25.17  ? 599 GLN F CD  1 
ATOM   17806 O OE1 . GLN F 1 397 ? 38.492  3.309   40.178 1.00 27.31  ? 599 GLN F OE1 1 
ATOM   17807 N NE2 . GLN F 1 397 ? 38.810  2.680   42.304 1.00 24.25  ? 599 GLN F NE2 1 
ATOM   17808 N N   . GLY F 1 398 ? 37.535  -0.683  42.723 1.00 25.06  ? 600 GLY F N   1 
ATOM   17809 C CA  . GLY F 1 398 ? 37.342  -1.089  44.094 1.00 23.64  ? 600 GLY F CA  1 
ATOM   17810 C C   . GLY F 1 398 ? 36.886  0.063   44.959 1.00 23.45  ? 600 GLY F C   1 
ATOM   17811 O O   . GLY F 1 398 ? 36.711  1.188   44.500 1.00 23.01  ? 600 GLY F O   1 
ATOM   17812 N N   . ILE F 1 399 ? 36.700  -0.236  46.244 1.00 25.00  ? 601 ILE F N   1 
ATOM   17813 C CA  . ILE F 1 399 ? 36.198  0.760   47.181 1.00 24.28  ? 601 ILE F CA  1 
ATOM   17814 C C   . ILE F 1 399 ? 37.175  1.919   47.285 1.00 23.86  ? 601 ILE F C   1 
ATOM   17815 O O   . ILE F 1 399 ? 38.394  1.728   47.281 1.00 24.53  ? 601 ILE F O   1 
ATOM   17816 C CB  . ILE F 1 399 ? 35.935  0.108   48.549 1.00 23.92  ? 601 ILE F CB  1 
ATOM   17817 C CG1 . ILE F 1 399 ? 34.806  -0.915  48.446 1.00 24.32  ? 601 ILE F CG1 1 
ATOM   17818 C CG2 . ILE F 1 399 ? 35.592  1.144   49.579 1.00 25.38  ? 601 ILE F CG2 1 
ATOM   17819 C CD1 . ILE F 1 399 ? 33.494  -0.309  48.015 1.00 23.18  ? 601 ILE F CD1 1 
ATOM   17820 N N   . LEU F 1 400 ? 36.632  3.133   47.342 1.00 23.16  ? 602 LEU F N   1 
ATOM   17821 C CA  . LEU F 1 400 ? 37.317  4.381   47.625 1.00 22.61  ? 602 LEU F CA  1 
ATOM   17822 C C   . LEU F 1 400 ? 36.624  5.076   48.788 1.00 23.68  ? 602 LEU F C   1 
ATOM   17823 O O   . LEU F 1 400 ? 35.411  4.927   48.962 1.00 23.35  ? 602 LEU F O   1 
ATOM   17824 C CB  . LEU F 1 400 ? 37.314  5.315   46.410 1.00 23.74  ? 602 LEU F CB  1 
ATOM   17825 C CG  . LEU F 1 400 ? 38.059  4.857   45.162 1.00 23.01  ? 602 LEU F CG  1 
ATOM   17826 C CD1 . LEU F 1 400 ? 37.805  5.823   44.028 1.00 22.48  ? 602 LEU F CD1 1 
ATOM   17827 C CD2 . LEU F 1 400 ? 39.539  4.752   45.443 1.00 21.97  ? 602 LEU F CD2 1 
ATOM   17828 N N   . PRO F 1 401 ? 37.357  5.819   49.612 1.00 21.85  ? 603 PRO F N   1 
ATOM   17829 C CA  . PRO F 1 401 ? 36.700  6.579   50.678 1.00 22.04  ? 603 PRO F CA  1 
ATOM   17830 C C   . PRO F 1 401 ? 35.726  7.586   50.086 1.00 22.25  ? 603 PRO F C   1 
ATOM   17831 O O   . PRO F 1 401 ? 36.071  8.357   49.190 1.00 22.66  ? 603 PRO F O   1 
ATOM   17832 C CB  . PRO F 1 401 ? 37.867  7.267   51.390 1.00 21.20  ? 603 PRO F CB  1 
ATOM   17833 C CG  . PRO F 1 401 ? 39.030  6.390   51.112 1.00 23.68  ? 603 PRO F CG  1 
ATOM   17834 C CD  . PRO F 1 401 ? 38.822  5.893   49.715 1.00 22.34  ? 603 PRO F CD  1 
ATOM   17835 N N   . GLY F 1 402 ? 34.499  7.569   50.590 1.00 23.28  ? 604 GLY F N   1 
ATOM   17836 C CA  . GLY F 1 402 ? 33.465  8.443   50.088 1.00 22.25  ? 604 GLY F CA  1 
ATOM   17837 C C   . GLY F 1 402 ? 32.451  7.799   49.172 1.00 22.10  ? 604 GLY F C   1 
ATOM   17838 O O   . GLY F 1 402 ? 31.544  8.493   48.706 1.00 22.34  ? 604 GLY F O   1 
ATOM   17839 N N   . MET F 1 403 ? 32.570  6.506   48.899 1.00 19.24  ? 605 MET F N   1 
ATOM   17840 C CA  . MET F 1 403 ? 31.560  5.821   48.111 1.00 17.92  ? 605 MET F CA  1 
ATOM   17841 C C   . MET F 1 403 ? 30.314  5.548   48.940 1.00 17.27  ? 605 MET F C   1 
ATOM   17842 O O   . MET F 1 403 ? 30.374  5.362   50.157 1.00 17.85  ? 605 MET F O   1 
ATOM   17843 C CB  . MET F 1 403 ? 32.092  4.503   47.551 1.00 16.79  ? 605 MET F CB  1 
ATOM   17844 C CG  . MET F 1 403 ? 33.055  4.647   46.401 1.00 17.54  ? 605 MET F CG  1 
ATOM   17845 S SD  . MET F 1 403 ? 33.601  3.046   45.797 1.00 20.21  ? 605 MET F SD  1 
ATOM   17846 C CE  . MET F 1 403 ? 34.600  3.559   44.410 1.00 20.49  ? 605 MET F CE  1 
ATOM   17847 N N   . VAL F 1 404 ? 29.172  5.543   48.260 1.00 17.55  ? 606 VAL F N   1 
ATOM   17848 C CA  . VAL F 1 404 ? 27.910  5.083   48.818 1.00 17.09  ? 606 VAL F CA  1 
ATOM   17849 C C   . VAL F 1 404 ? 27.265  4.178   47.780 1.00 17.19  ? 606 VAL F C   1 
ATOM   17850 O O   . VAL F 1 404 ? 27.405  4.394   46.573 1.00 19.42  ? 606 VAL F O   1 
ATOM   17851 C CB  . VAL F 1 404 ? 26.974  6.250   49.204 1.00 15.08  ? 606 VAL F CB  1 
ATOM   17852 C CG1 . VAL F 1 404 ? 27.580  7.067   50.329 1.00 18.82  ? 606 VAL F CG1 1 
ATOM   17853 C CG2 . VAL F 1 404 ? 26.703  7.130   48.010 1.00 14.16  ? 606 VAL F CG2 1 
ATOM   17854 N N   . TRP F 1 405 ? 26.574  3.143   48.250 1.00 16.20  ? 607 TRP F N   1 
ATOM   17855 C CA  . TRP F 1 405 ? 26.012  2.162   47.334 1.00 16.12  ? 607 TRP F CA  1 
ATOM   17856 C C   . TRP F 1 405 ? 24.801  1.502   47.971 1.00 16.86  ? 607 TRP F C   1 
ATOM   17857 O O   . TRP F 1 405 ? 24.580  1.595   49.180 1.00 16.52  ? 607 TRP F O   1 
ATOM   17858 C CB  . TRP F 1 405 ? 27.045  1.102   46.937 1.00 15.52  ? 607 TRP F CB  1 
ATOM   17859 C CG  . TRP F 1 405 ? 27.565  0.300   48.078 1.00 16.02  ? 607 TRP F CG  1 
ATOM   17860 C CD1 . TRP F 1 405 ? 27.053  -0.866  48.556 1.00 16.94  ? 607 TRP F CD1 1 
ATOM   17861 C CD2 . TRP F 1 405 ? 28.712  0.594   48.879 1.00 15.99  ? 607 TRP F CD2 1 
ATOM   17862 N NE1 . TRP F 1 405 ? 27.801  -1.312  49.613 1.00 16.46  ? 607 TRP F NE1 1 
ATOM   17863 C CE2 . TRP F 1 405 ? 28.828  -0.433  49.831 1.00 16.87  ? 607 TRP F CE2 1 
ATOM   17864 C CE3 . TRP F 1 405 ? 29.649  1.629   48.887 1.00 15.31  ? 607 TRP F CE3 1 
ATOM   17865 C CZ2 . TRP F 1 405 ? 29.843  -0.458  50.779 1.00 16.39  ? 607 TRP F CZ2 1 
ATOM   17866 C CZ3 . TRP F 1 405 ? 30.654  1.603   49.826 1.00 16.86  ? 607 TRP F CZ3 1 
ATOM   17867 C CH2 . TRP F 1 405 ? 30.744  0.567   50.761 1.00 16.66  ? 607 TRP F CH2 1 
ATOM   17868 N N   . GLN F 1 406 ? 24.020  0.833   47.129 1.00 16.72  ? 608 GLN F N   1 
ATOM   17869 C CA  . GLN F 1 406 ? 22.874  0.044   47.549 1.00 17.96  ? 608 GLN F CA  1 
ATOM   17870 C C   . GLN F 1 406 ? 23.151  -1.439  47.354 1.00 18.42  ? 608 GLN F C   1 
ATOM   17871 O O   . GLN F 1 406 ? 23.903  -1.840  46.463 1.00 17.61  ? 608 GLN F O   1 
ATOM   17872 C CB  . GLN F 1 406 ? 21.619  0.433   46.768 1.00 12.21  ? 608 GLN F CB  1 
ATOM   17873 C CG  . GLN F 1 406 ? 21.058  1.782   47.126 1.00 17.85  ? 608 GLN F CG  1 
ATOM   17874 C CD  . GLN F 1 406 ? 20.541  1.825   48.543 1.00 21.50  ? 608 GLN F CD  1 
ATOM   17875 O OE1 . GLN F 1 406 ? 19.883  0.898   49.004 1.00 24.78  ? 608 GLN F OE1 1 
ATOM   17876 N NE2 . GLN F 1 406 ? 20.849  2.896   49.247 1.00 17.78  ? 608 GLN F NE2 1 
ATOM   17877 N N   . ASP F 1 407 ? 22.532  -2.249  48.203 1.00 18.86  ? 609 ASP F N   1 
ATOM   17878 C CA  . ASP F 1 407 ? 22.669  -3.691  48.123 1.00 19.64  ? 609 ASP F CA  1 
ATOM   17879 C C   . ASP F 1 407 ? 21.711  -4.240  47.073 1.00 18.73  ? 609 ASP F C   1 
ATOM   17880 O O   . ASP F 1 407 ? 20.953  -3.506  46.438 1.00 17.28  ? 609 ASP F O   1 
ATOM   17881 C CB  . ASP F 1 407 ? 22.417  -4.315  49.491 1.00 19.94  ? 609 ASP F CB  1 
ATOM   17882 C CG  . ASP F 1 407 ? 23.499  -3.970  50.491 1.00 25.31  ? 609 ASP F CG  1 
ATOM   17883 O OD1 . ASP F 1 407 ? 24.602  -3.578  50.060 1.00 26.31  ? 609 ASP F OD1 1 
ATOM   17884 O OD2 . ASP F 1 407 ? 23.242  -4.071  51.707 1.00 27.35  ? 609 ASP F OD2 1 
ATOM   17885 N N   . ARG F 1 408 ? 21.739  -5.549  46.878 1.00 18.54  ? 610 ARG F N   1 
ATOM   17886 C CA  . ARG F 1 408 ? 20.830  -6.149  45.920 1.00 18.88  ? 610 ARG F CA  1 
ATOM   17887 C C   . ARG F 1 408 ? 19.464  -6.378  46.553 1.00 18.90  ? 610 ARG F C   1 
ATOM   17888 O O   . ARG F 1 408 ? 19.344  -6.669  47.746 1.00 18.34  ? 610 ARG F O   1 
ATOM   17889 C CB  . ARG F 1 408 ? 21.397  -7.458  45.375 1.00 15.94  ? 610 ARG F CB  1 
ATOM   17890 C CG  . ARG F 1 408 ? 20.551  -8.071  44.285 1.00 17.36  ? 610 ARG F CG  1 
ATOM   17891 C CD  . ARG F 1 408 ? 21.216  -9.277  43.694 1.00 19.49  ? 610 ARG F CD  1 
ATOM   17892 N NE  . ARG F 1 408 ? 22.452  -8.896  43.027 1.00 22.39  ? 610 ARG F NE  1 
ATOM   17893 C CZ  . ARG F 1 408 ? 22.516  -8.428  41.787 1.00 23.67  ? 610 ARG F CZ  1 
ATOM   17894 N NH1 . ARG F 1 408 ? 21.410  -8.283  41.073 1.00 24.44  ? 610 ARG F NH1 1 
ATOM   17895 N NH2 . ARG F 1 408 ? 23.685  -8.105  41.260 1.00 24.68  ? 610 ARG F NH2 1 
ATOM   17896 N N   . ASP F 1 409 ? 18.431  -6.230  45.736 1.00 19.09  ? 611 ASP F N   1 
ATOM   17897 C CA  . ASP F 1 409 ? 17.056  -6.302  46.185 1.00 19.53  ? 611 ASP F CA  1 
ATOM   17898 C C   . ASP F 1 409 ? 16.677  -7.745  46.519 1.00 19.28  ? 611 ASP F C   1 
ATOM   17899 O O   . ASP F 1 409 ? 17.284  -8.703  46.035 1.00 19.08  ? 611 ASP F O   1 
ATOM   17900 C CB  . ASP F 1 409 ? 16.140  -5.731  45.103 1.00 16.48  ? 611 ASP F CB  1 
ATOM   17901 C CG  . ASP F 1 409 ? 14.731  -5.546  45.574 1.00 18.82  ? 611 ASP F CG  1 
ATOM   17902 O OD1 . ASP F 1 409 ? 14.490  -5.775  46.768 1.00 21.37  ? 611 ASP F OD1 1 
ATOM   17903 O OD2 . ASP F 1 409 ? 13.867  -5.172  44.756 1.00 17.86  ? 611 ASP F OD2 1 
ATOM   17904 N N   . VAL F 1 410 ? 15.666  -7.890  47.375 1.00 17.73  ? 612 VAL F N   1 
ATOM   17905 C CA  . VAL F 1 410 ? 15.132  -9.195  47.744 1.00 16.35  ? 612 VAL F CA  1 
ATOM   17906 C C   . VAL F 1 410 ? 13.794  -9.371  47.051 1.00 15.18  ? 612 VAL F C   1 
ATOM   17907 O O   . VAL F 1 410 ? 13.067  -8.405  46.803 1.00 14.42  ? 612 VAL F O   1 
ATOM   17908 C CB  . VAL F 1 410 ? 14.985  -9.369  49.269 1.00 14.81  ? 612 VAL F CB  1 
ATOM   17909 C CG1 . VAL F 1 410 ? 16.329  -9.228  49.955 1.00 14.17  ? 612 VAL F CG1 1 
ATOM   17910 C CG2 . VAL F 1 410 ? 13.965  -8.399  49.833 1.00 17.62  ? 612 VAL F CG2 1 
ATOM   17911 N N   . TYR F 1 411 ? 13.468  -10.614 46.725 1.00 14.94  ? 613 TYR F N   1 
ATOM   17912 C CA  . TYR F 1 411 ? 12.272  -10.922 45.963 1.00 14.56  ? 613 TYR F CA  1 
ATOM   17913 C C   . TYR F 1 411 ? 11.427  -11.945 46.707 1.00 14.23  ? 613 TYR F C   1 
ATOM   17914 O O   . TYR F 1 411 ? 11.896  -12.616 47.628 1.00 15.59  ? 613 TYR F O   1 
ATOM   17915 C CB  . TYR F 1 411 ? 12.644  -11.430 44.565 1.00 11.30  ? 613 TYR F CB  1 
ATOM   17916 C CG  . TYR F 1 411 ? 13.389  -10.394 43.761 1.00 14.80  ? 613 TYR F CG  1 
ATOM   17917 C CD1 . TYR F 1 411 ? 12.715  -9.492  42.958 1.00 16.20  ? 613 TYR F CD1 1 
ATOM   17918 C CD2 . TYR F 1 411 ? 14.768  -10.294 43.840 1.00 15.87  ? 613 TYR F CD2 1 
ATOM   17919 C CE1 . TYR F 1 411 ? 13.394  -8.534  42.239 1.00 18.26  ? 613 TYR F CE1 1 
ATOM   17920 C CE2 . TYR F 1 411 ? 15.454  -9.341  43.130 1.00 19.37  ? 613 TYR F CE2 1 
ATOM   17921 C CZ  . TYR F 1 411 ? 14.763  -8.462  42.330 1.00 19.85  ? 613 TYR F CZ  1 
ATOM   17922 O OH  . TYR F 1 411 ? 15.445  -7.508  41.615 1.00 21.81  ? 613 TYR F OH  1 
ATOM   17923 N N   . LEU F 1 412 ? 10.157  -12.036 46.310 1.00 13.58  ? 614 LEU F N   1 
ATOM   17924 C CA  . LEU F 1 412 ? 9.278   -13.057 46.869 1.00 13.04  ? 614 LEU F CA  1 
ATOM   17925 C C   . LEU F 1 412 ? 9.853   -14.449 46.634 1.00 14.13  ? 614 LEU F C   1 
ATOM   17926 O O   . LEU F 1 412 ? 9.743   -15.330 47.493 1.00 15.42  ? 614 LEU F O   1 
ATOM   17927 C CB  . LEU F 1 412 ? 7.886   -12.935 46.247 1.00 11.34  ? 614 LEU F CB  1 
ATOM   17928 C CG  . LEU F 1 412 ? 6.693   -13.694 46.829 1.00 11.08  ? 614 LEU F CG  1 
ATOM   17929 C CD1 . LEU F 1 412 ? 6.782   -13.769 48.335 1.00 11.24  ? 614 LEU F CD1 1 
ATOM   17930 C CD2 . LEU F 1 412 ? 5.414   -12.999 46.426 1.00 9.60   ? 614 LEU F CD2 1 
ATOM   17931 N N   . GLN F 1 413 ? 10.482  -14.658 45.478 1.00 15.17  ? 615 GLN F N   1 
ATOM   17932 C CA  . GLN F 1 413 ? 11.129  -15.917 45.148 1.00 15.02  ? 615 GLN F CA  1 
ATOM   17933 C C   . GLN F 1 413 ? 12.548  -16.026 45.683 1.00 14.59  ? 615 GLN F C   1 
ATOM   17934 O O   . GLN F 1 413 ? 13.099  -17.130 45.700 1.00 15.18  ? 615 GLN F O   1 
ATOM   17935 C CB  . GLN F 1 413 ? 11.182  -16.112 43.630 1.00 12.23  ? 615 GLN F CB  1 
ATOM   17936 C CG  . GLN F 1 413 ? 9.850   -16.128 42.933 1.00 17.63  ? 615 GLN F CG  1 
ATOM   17937 C CD  . GLN F 1 413 ? 9.400   -14.747 42.525 1.00 20.52  ? 615 GLN F CD  1 
ATOM   17938 O OE1 . GLN F 1 413 ? 10.102  -13.764 42.747 1.00 19.27  ? 615 GLN F OE1 1 
ATOM   17939 N NE2 . GLN F 1 413 ? 8.225   -14.663 41.917 1.00 23.11  ? 615 GLN F NE2 1 
ATOM   17940 N N   . GLY F 1 414 ? 13.155  -14.924 46.108 1.00 18.39  ? 616 GLY F N   1 
ATOM   17941 C CA  . GLY F 1 414 ? 14.563  -14.909 46.426 1.00 16.75  ? 616 GLY F CA  1 
ATOM   17942 C C   . GLY F 1 414 ? 14.888  -15.492 47.784 1.00 15.71  ? 616 GLY F C   1 
ATOM   17943 O O   . GLY F 1 414 ? 14.004  -15.771 48.596 1.00 15.45  ? 616 GLY F O   1 
ATOM   17944 N N   . PRO F 1 415 ? 16.177  -15.681 48.056 1.00 16.72  ? 617 PRO F N   1 
ATOM   17945 C CA  . PRO F 1 415 ? 16.591  -16.229 49.350 1.00 16.91  ? 617 PRO F CA  1 
ATOM   17946 C C   . PRO F 1 415 ? 16.527  -15.184 50.452 1.00 17.28  ? 617 PRO F C   1 
ATOM   17947 O O   . PRO F 1 415 ? 16.554  -13.978 50.211 1.00 17.32  ? 617 PRO F O   1 
ATOM   17948 C CB  . PRO F 1 415 ? 18.030  -16.676 49.095 1.00 16.26  ? 617 PRO F CB  1 
ATOM   17949 C CG  . PRO F 1 415 ? 18.504  -15.756 48.030 1.00 16.98  ? 617 PRO F CG  1 
ATOM   17950 C CD  . PRO F 1 415 ? 17.321  -15.478 47.152 1.00 15.59  ? 617 PRO F CD  1 
ATOM   17951 N N   . ILE F 1 416 ? 16.447  -15.674 51.687 1.00 18.94  ? 618 ILE F N   1 
ATOM   17952 C CA  . ILE F 1 416 ? 16.271  -14.803 52.843 1.00 17.17  ? 618 ILE F CA  1 
ATOM   17953 C C   . ILE F 1 416 ? 17.619  -14.472 53.466 1.00 18.00  ? 618 ILE F C   1 
ATOM   17954 O O   . ILE F 1 416 ? 18.015  -13.306 53.519 1.00 18.47  ? 618 ILE F O   1 
ATOM   17955 C CB  . ILE F 1 416 ? 15.329  -15.429 53.884 1.00 20.99  ? 618 ILE F CB  1 
ATOM   17956 C CG1 . ILE F 1 416 ? 13.922  -15.573 53.314 1.00 20.23  ? 618 ILE F CG1 1 
ATOM   17957 C CG2 . ILE F 1 416 ? 15.286  -14.576 55.134 1.00 17.46  ? 618 ILE F CG2 1 
ATOM   17958 C CD1 . ILE F 1 416 ? 13.002  -16.367 54.193 1.00 18.79  ? 618 ILE F CD1 1 
ATOM   17959 N N   . TRP F 1 417 ? 18.324  -15.478 53.967 1.00 23.44  ? 619 TRP F N   1 
ATOM   17960 C CA  . TRP F 1 417 ? 19.598  -15.239 54.622 1.00 23.70  ? 619 TRP F CA  1 
ATOM   17961 C C   . TRP F 1 417 ? 20.716  -15.981 53.904 1.00 24.27  ? 619 TRP F C   1 
ATOM   17962 O O   . TRP F 1 417 ? 20.503  -16.697 52.924 1.00 23.81  ? 619 TRP F O   1 
ATOM   17963 C CB  . TRP F 1 417 ? 19.565  -15.664 56.097 1.00 24.23  ? 619 TRP F CB  1 
ATOM   17964 C CG  . TRP F 1 417 ? 19.372  -17.126 56.277 1.00 25.51  ? 619 TRP F CG  1 
ATOM   17965 C CD1 . TRP F 1 417 ? 20.343  -18.077 56.317 1.00 26.82  ? 619 TRP F CD1 1 
ATOM   17966 C CD2 . TRP F 1 417 ? 18.132  -17.811 56.456 1.00 25.53  ? 619 TRP F CD2 1 
ATOM   17967 N NE1 . TRP F 1 417 ? 19.787  -19.316 56.495 1.00 27.51  ? 619 TRP F NE1 1 
ATOM   17968 C CE2 . TRP F 1 417 ? 18.428  -19.179 56.585 1.00 26.61  ? 619 TRP F CE2 1 
ATOM   17969 C CE3 . TRP F 1 417 ? 16.799  -17.402 56.513 1.00 24.18  ? 619 TRP F CE3 1 
ATOM   17970 C CZ2 . TRP F 1 417 ? 17.444  -20.136 56.770 1.00 27.12  ? 619 TRP F CZ2 1 
ATOM   17971 C CZ3 . TRP F 1 417 ? 15.826  -18.352 56.693 1.00 25.65  ? 619 TRP F CZ3 1 
ATOM   17972 C CH2 . TRP F 1 417 ? 16.152  -19.704 56.819 1.00 27.19  ? 619 TRP F CH2 1 
ATOM   17973 N N   . ALA F 1 418 ? 21.925  -15.788 54.423 1.00 27.02  ? 620 ALA F N   1 
ATOM   17974 C CA  . ALA F 1 418 ? 23.108  -16.519 54.004 1.00 28.20  ? 620 ALA F CA  1 
ATOM   17975 C C   . ALA F 1 418 ? 24.089  -16.525 55.164 1.00 29.18  ? 620 ALA F C   1 
ATOM   17976 O O   . ALA F 1 418 ? 24.075  -15.634 56.014 1.00 29.04  ? 620 ALA F O   1 
ATOM   17977 C CB  . ALA F 1 418 ? 23.757  -15.901 52.764 1.00 26.42  ? 620 ALA F CB  1 
ATOM   17978 N N   . LYS F 1 419 ? 24.949  -17.535 55.197 1.00 28.57  ? 621 LYS F N   1 
ATOM   17979 C CA  . LYS F 1 419 ? 25.955  -17.634 56.243 1.00 29.15  ? 621 LYS F CA  1 
ATOM   17980 C C   . LYS F 1 419 ? 27.209  -16.888 55.808 1.00 30.01  ? 621 LYS F C   1 
ATOM   17981 O O   . LYS F 1 419 ? 27.777  -17.181 54.752 1.00 30.04  ? 621 LYS F O   1 
ATOM   17982 C CB  . LYS F 1 419 ? 26.290  -19.088 56.561 1.00 30.26  ? 621 LYS F CB  1 
ATOM   17983 C CG  . LYS F 1 419 ? 27.272  -19.218 57.705 1.00 31.63  ? 621 LYS F CG  1 
ATOM   17984 C CD  . LYS F 1 419 ? 27.485  -20.651 58.120 1.00 33.67  ? 621 LYS F CD  1 
ATOM   17985 C CE  . LYS F 1 419 ? 28.486  -20.726 59.253 1.00 36.58  ? 621 LYS F CE  1 
ATOM   17986 N NZ  . LYS F 1 419 ? 29.855  -20.374 58.798 1.00 39.27  ? 621 LYS F NZ  1 
ATOM   17987 N N   . ILE F 1 420 ? 27.631  -15.928 56.616 1.00 29.63  ? 622 ILE F N   1 
ATOM   17988 C CA  . ILE F 1 420 ? 28.909  -15.256 56.370 1.00 30.14  ? 622 ILE F CA  1 
ATOM   17989 C C   . ILE F 1 420 ? 30.036  -16.261 56.569 1.00 32.06  ? 622 ILE F C   1 
ATOM   17990 O O   . ILE F 1 420 ? 30.154  -16.841 57.663 1.00 32.88  ? 622 ILE F O   1 
ATOM   17991 C CB  . ILE F 1 420 ? 29.071  -14.063 57.308 1.00 31.48  ? 622 ILE F CB  1 
ATOM   17992 C CG1 . ILE F 1 420 ? 28.000  -13.010 57.029 1.00 30.31  ? 622 ILE F CG1 1 
ATOM   17993 C CG2 . ILE F 1 420 ? 30.452  -13.458 57.159 1.00 31.47  ? 622 ILE F CG2 1 
ATOM   17994 C CD1 . ILE F 1 420 ? 27.922  -11.941 58.090 1.00 29.10  ? 622 ILE F CD1 1 
ATOM   17995 N N   . PRO F 1 421 ? 30.868  -16.515 55.562 1.00 30.82  ? 623 PRO F N   1 
ATOM   17996 C CA  . PRO F 1 421 ? 31.962  -17.473 55.738 1.00 31.75  ? 623 PRO F CA  1 
ATOM   17997 C C   . PRO F 1 421 ? 32.868  -17.043 56.878 1.00 33.77  ? 623 PRO F C   1 
ATOM   17998 O O   . PRO F 1 421 ? 33.045  -15.853 57.145 1.00 34.42  ? 623 PRO F O   1 
ATOM   17999 C CB  . PRO F 1 421 ? 32.692  -17.423 54.391 1.00 29.05  ? 623 PRO F CB  1 
ATOM   18000 C CG  . PRO F 1 421 ? 31.664  -16.940 53.429 1.00 29.01  ? 623 PRO F CG  1 
ATOM   18001 C CD  . PRO F 1 421 ? 30.840  -15.963 54.199 1.00 28.52  ? 623 PRO F CD  1 
ATOM   18002 N N   . HIS F 1 422 ? 33.458  -18.024 57.550 1.00 34.80  ? 624 HIS F N   1 
ATOM   18003 C CA  . HIS F 1 422 ? 34.257  -17.745 58.735 1.00 36.24  ? 624 HIS F CA  1 
ATOM   18004 C C   . HIS F 1 422 ? 35.692  -17.527 58.281 1.00 34.91  ? 624 HIS F C   1 
ATOM   18005 O O   . HIS F 1 422 ? 36.386  -18.476 57.908 1.00 34.31  ? 624 HIS F O   1 
ATOM   18006 C CB  . HIS F 1 422 ? 34.158  -18.891 59.736 1.00 34.51  ? 624 HIS F CB  1 
ATOM   18007 C CG  . HIS F 1 422 ? 34.873  -18.630 61.023 1.00 39.58  ? 624 HIS F CG  1 
ATOM   18008 N ND1 . HIS F 1 422 ? 34.526  -17.600 61.869 1.00 42.49  ? 624 HIS F ND1 1 
ATOM   18009 C CD2 . HIS F 1 422 ? 35.913  -19.265 61.610 1.00 41.80  ? 624 HIS F CD2 1 
ATOM   18010 C CE1 . HIS F 1 422 ? 35.323  -17.611 62.922 1.00 44.04  ? 624 HIS F CE1 1 
ATOM   18011 N NE2 . HIS F 1 422 ? 36.174  -18.611 62.789 1.00 44.36  ? 624 HIS F NE2 1 
ATOM   18012 N N   . THR F 1 423 ? 36.136  -16.275 58.334 1.00 35.74  ? 625 THR F N   1 
ATOM   18013 C CA  . THR F 1 423 ? 37.402  -15.862 57.748 1.00 35.88  ? 625 THR F CA  1 
ATOM   18014 C C   . THR F 1 423 ? 38.013  -14.770 58.611 1.00 36.04  ? 625 THR F C   1 
ATOM   18015 O O   . THR F 1 423 ? 37.367  -14.220 59.505 1.00 35.79  ? 625 THR F O   1 
ATOM   18016 C CB  . THR F 1 423 ? 37.232  -15.369 56.304 1.00 35.40  ? 625 THR F CB  1 
ATOM   18017 O OG1 . THR F 1 423 ? 36.225  -14.351 56.256 1.00 34.91  ? 625 THR F OG1 1 
ATOM   18018 C CG2 . THR F 1 423 ? 36.868  -16.506 55.365 1.00 34.37  ? 625 THR F CG2 1 
ATOM   18019 N N   . ASP F 1 424 ? 39.284  -14.473 58.341 1.00 36.00  ? 626 ASP F N   1 
ATOM   18020 C CA  . ASP F 1 424 ? 39.963  -13.400 59.059 1.00 36.38  ? 626 ASP F CA  1 
ATOM   18021 C C   . ASP F 1 424 ? 39.301  -12.057 58.794 1.00 35.33  ? 626 ASP F C   1 
ATOM   18022 O O   . ASP F 1 424 ? 39.189  -11.219 59.695 1.00 36.27  ? 626 ASP F O   1 
ATOM   18023 C CB  . ASP F 1 424 ? 41.438  -13.357 58.666 1.00 39.90  ? 626 ASP F CB  1 
ATOM   18024 C CG  . ASP F 1 424 ? 42.222  -14.512 59.238 1.00 43.81  ? 626 ASP F CG  1 
ATOM   18025 O OD1 . ASP F 1 424 ? 41.719  -15.150 60.183 1.00 47.64  ? 626 ASP F OD1 1 
ATOM   18026 O OD2 . ASP F 1 424 ? 43.336  -14.786 58.745 1.00 45.97  ? 626 ASP F OD2 1 
ATOM   18027 N N   . GLY F 1 425 ? 38.850  -11.832 57.565 1.00 34.87  ? 627 GLY F N   1 
ATOM   18028 C CA  . GLY F 1 425 ? 38.269  -10.550 57.222 1.00 32.37  ? 627 GLY F CA  1 
ATOM   18029 C C   . GLY F 1 425 ? 37.244  -10.654 56.116 1.00 31.69  ? 627 GLY F C   1 
ATOM   18030 O O   . GLY F 1 425 ? 37.220  -11.612 55.338 1.00 31.80  ? 627 GLY F O   1 
ATOM   18031 N N   . ASN F 1 426 ? 36.388  -9.638  56.066 1.00 28.64  ? 628 ASN F N   1 
ATOM   18032 C CA  . ASN F 1 426 ? 35.386  -9.490  55.025 1.00 28.26  ? 628 ASN F CA  1 
ATOM   18033 C C   . ASN F 1 426 ? 34.997  -8.024  54.960 1.00 27.67  ? 628 ASN F C   1 
ATOM   18034 O O   . ASN F 1 426 ? 35.252  -7.259  55.893 1.00 27.01  ? 628 ASN F O   1 
ATOM   18035 C CB  . ASN F 1 426 ? 34.173  -10.398 55.282 1.00 29.86  ? 628 ASN F CB  1 
ATOM   18036 C CG  . ASN F 1 426 ? 33.508  -10.141 56.627 1.00 29.26  ? 628 ASN F CG  1 
ATOM   18037 O OD1 . ASN F 1 426 ? 33.415  -9.009  57.092 1.00 27.59  ? 628 ASN F OD1 1 
ATOM   18038 N ND2 . ASN F 1 426 ? 33.063  -11.211 57.269 1.00 30.17  ? 628 ASN F ND2 1 
ATOM   18039 N N   . PHE F 1 427 ? 34.387  -7.627  53.850 1.00 25.46  ? 629 PHE F N   1 
ATOM   18040 C CA  . PHE F 1 427 ? 33.906  -6.260  53.719 1.00 25.05  ? 629 PHE F CA  1 
ATOM   18041 C C   . PHE F 1 427 ? 32.462  -6.259  53.252 1.00 26.55  ? 629 PHE F C   1 
ATOM   18042 O O   . PHE F 1 427 ? 32.140  -6.845  52.215 1.00 26.53  ? 629 PHE F O   1 
ATOM   18043 C CB  . PHE F 1 427 ? 34.756  -5.438  52.756 1.00 23.83  ? 629 PHE F CB  1 
ATOM   18044 C CG  . PHE F 1 427 ? 34.249  -4.043  52.573 1.00 24.26  ? 629 PHE F CG  1 
ATOM   18045 C CD1 . PHE F 1 427 ? 34.498  -3.077  53.527 1.00 22.64  ? 629 PHE F CD1 1 
ATOM   18046 C CD2 . PHE F 1 427 ? 33.502  -3.702  51.460 1.00 23.95  ? 629 PHE F CD2 1 
ATOM   18047 C CE1 . PHE F 1 427 ? 34.024  -1.797  53.370 1.00 22.56  ? 629 PHE F CE1 1 
ATOM   18048 C CE2 . PHE F 1 427 ? 33.028  -2.425  51.299 1.00 24.04  ? 629 PHE F CE2 1 
ATOM   18049 C CZ  . PHE F 1 427 ? 33.288  -1.471  52.255 1.00 23.48  ? 629 PHE F CZ  1 
ATOM   18050 N N   . HIS F 1 428 ? 31.613  -5.565  54.006 1.00 22.82  ? 630 HIS F N   1 
ATOM   18051 C CA  . HIS F 1 428 ? 30.185  -5.436  53.761 1.00 23.93  ? 630 HIS F CA  1 
ATOM   18052 C C   . HIS F 1 428 ? 29.625  -6.833  53.536 1.00 24.46  ? 630 HIS F C   1 
ATOM   18053 O O   . HIS F 1 428 ? 29.249  -7.187  52.413 1.00 25.06  ? 630 HIS F O   1 
ATOM   18054 C CB  . HIS F 1 428 ? 29.917  -4.520  52.568 1.00 21.84  ? 630 HIS F CB  1 
ATOM   18055 C CG  . HIS F 1 428 ? 28.500  -4.052  52.470 1.00 23.28  ? 630 HIS F CG  1 
ATOM   18056 N ND1 . HIS F 1 428 ? 27.921  -3.235  53.416 1.00 23.87  ? 630 HIS F ND1 1 
ATOM   18057 C CD2 . HIS F 1 428 ? 27.547  -4.281  51.538 1.00 23.54  ? 630 HIS F CD2 1 
ATOM   18058 C CE1 . HIS F 1 428 ? 26.673  -2.981  53.070 1.00 24.36  ? 630 HIS F CE1 1 
ATOM   18059 N NE2 . HIS F 1 428 ? 26.420  -3.605  51.935 1.00 24.16  ? 630 HIS F NE2 1 
ATOM   18060 N N   . PRO F 1 429 ? 29.563  -7.648  54.585 1.00 27.32  ? 631 PRO F N   1 
ATOM   18061 C CA  . PRO F 1 429 ? 29.299  -9.085  54.427 1.00 26.94  ? 631 PRO F CA  1 
ATOM   18062 C C   . PRO F 1 429 ? 27.966  -9.445  53.787 1.00 26.92  ? 631 PRO F C   1 
ATOM   18063 O O   . PRO F 1 429 ? 27.731  -10.626 53.516 1.00 28.25  ? 631 PRO F O   1 
ATOM   18064 C CB  . PRO F 1 429 ? 29.390  -9.606  55.866 1.00 29.67  ? 631 PRO F CB  1 
ATOM   18065 C CG  . PRO F 1 429 ? 29.071  -8.435  56.709 1.00 29.10  ? 631 PRO F CG  1 
ATOM   18066 C CD  . PRO F 1 429 ? 29.670  -7.264  56.001 1.00 29.16  ? 631 PRO F CD  1 
ATOM   18067 N N   . SER F 1 430 ? 27.075  -8.474  53.602 1.00 24.75  ? 632 SER F N   1 
ATOM   18068 C CA  . SER F 1 430 ? 25.773  -8.733  53.004 1.00 24.13  ? 632 SER F CA  1 
ATOM   18069 C C   . SER F 1 430 ? 25.921  -9.571  51.734 1.00 23.43  ? 632 SER F C   1 
ATOM   18070 O O   . SER F 1 430 ? 26.747  -9.240  50.872 1.00 23.49  ? 632 SER F O   1 
ATOM   18071 C CB  . SER F 1 430 ? 25.072  -7.414  52.678 1.00 21.07  ? 632 SER F CB  1 
ATOM   18072 O OG  . SER F 1 430 ? 23.834  -7.633  52.029 1.00 25.42  ? 632 SER F OG  1 
ATOM   18073 N N   . PRO F 1 431 ? 25.157  -10.652 51.585 1.00 23.17  ? 633 PRO F N   1 
ATOM   18074 C CA  . PRO F 1 431 ? 25.373  -11.562 50.458 1.00 22.88  ? 633 PRO F CA  1 
ATOM   18075 C C   . PRO F 1 431 ? 24.981  -10.936 49.131 1.00 22.94  ? 633 PRO F C   1 
ATOM   18076 O O   . PRO F 1 431 ? 24.103  -10.074 49.054 1.00 23.36  ? 633 PRO F O   1 
ATOM   18077 C CB  . PRO F 1 431 ? 24.475  -12.757 50.795 1.00 22.03  ? 633 PRO F CB  1 
ATOM   18078 C CG  . PRO F 1 431 ? 23.409  -12.186 51.644 1.00 23.20  ? 633 PRO F CG  1 
ATOM   18079 C CD  . PRO F 1 431 ? 24.057  -11.105 52.451 1.00 22.27  ? 633 PRO F CD  1 
ATOM   18080 N N   . LEU F 1 432 ? 25.649  -11.393 48.072 1.00 20.66  ? 634 LEU F N   1 
ATOM   18081 C CA  . LEU F 1 432 ? 25.505  -10.758 46.770 1.00 20.66  ? 634 LEU F CA  1 
ATOM   18082 C C   . LEU F 1 432 ? 24.249  -11.188 46.030 1.00 21.93  ? 634 LEU F C   1 
ATOM   18083 O O   . LEU F 1 432 ? 23.814  -10.473 45.125 1.00 21.96  ? 634 LEU F O   1 
ATOM   18084 C CB  . LEU F 1 432 ? 26.734  -11.038 45.909 1.00 22.51  ? 634 LEU F CB  1 
ATOM   18085 C CG  . LEU F 1 432 ? 28.032  -10.408 46.408 1.00 20.58  ? 634 LEU F CG  1 
ATOM   18086 C CD1 . LEU F 1 432 ? 29.199  -10.828 45.538 1.00 19.77  ? 634 LEU F CD1 1 
ATOM   18087 C CD2 . LEU F 1 432 ? 27.903  -8.905  46.449 1.00 17.81  ? 634 LEU F CD2 1 
ATOM   18088 N N   . MET F 1 433 ? 23.657  -12.329 46.375 1.00 19.63  ? 635 MET F N   1 
ATOM   18089 C CA  . MET F 1 433 ? 22.391  -12.699 45.755 1.00 20.42  ? 635 MET F CA  1 
ATOM   18090 C C   . MET F 1 433 ? 21.200  -12.040 46.430 1.00 20.58  ? 635 MET F C   1 
ATOM   18091 O O   . MET F 1 433 ? 20.067  -12.232 45.979 1.00 20.09  ? 635 MET F O   1 
ATOM   18092 C CB  . MET F 1 433 ? 22.204  -14.219 45.752 1.00 20.09  ? 635 MET F CB  1 
ATOM   18093 C CG  . MET F 1 433 ? 23.216  -14.960 44.896 1.00 22.49  ? 635 MET F CG  1 
ATOM   18094 S SD  . MET F 1 433 ? 22.862  -16.709 44.632 1.00 28.21  ? 635 MET F SD  1 
ATOM   18095 C CE  . MET F 1 433 ? 23.227  -17.418 46.230 1.00 27.29  ? 635 MET F CE  1 
ATOM   18096 N N   . GLY F 1 434 ? 21.427  -11.265 47.476 1.00 19.12  ? 636 GLY F N   1 
ATOM   18097 C CA  . GLY F 1 434 ? 20.369  -10.624 48.221 1.00 18.17  ? 636 GLY F CA  1 
ATOM   18098 C C   . GLY F 1 434 ? 20.124  -11.312 49.552 1.00 17.95  ? 636 GLY F C   1 
ATOM   18099 O O   . GLY F 1 434 ? 20.422  -12.492 49.746 1.00 19.19  ? 636 GLY F O   1 
ATOM   18100 N N   . GLY F 1 435 ? 19.562  -10.553 50.478 1.00 21.31  ? 637 GLY F N   1 
ATOM   18101 C CA  . GLY F 1 435 ? 19.222  -11.080 51.777 1.00 19.52  ? 637 GLY F CA  1 
ATOM   18102 C C   . GLY F 1 435 ? 20.165  -10.650 52.880 1.00 18.08  ? 637 GLY F C   1 
ATOM   18103 O O   . GLY F 1 435 ? 21.018  -9.774  52.725 1.00 17.69  ? 637 GLY F O   1 
ATOM   18104 N N   . PHE F 1 436 ? 19.995  -11.299 54.027 1.00 22.28  ? 638 PHE F N   1 
ATOM   18105 C CA  . PHE F 1 436 ? 20.646  -10.922 55.273 1.00 22.06  ? 638 PHE F CA  1 
ATOM   18106 C C   . PHE F 1 436 ? 21.827  -11.848 55.523 1.00 23.73  ? 638 PHE F C   1 
ATOM   18107 O O   . PHE F 1 436 ? 21.642  -13.055 55.703 1.00 25.66  ? 638 PHE F O   1 
ATOM   18108 C CB  . PHE F 1 436 ? 19.657  -11.004 56.434 1.00 20.84  ? 638 PHE F CB  1 
ATOM   18109 C CG  . PHE F 1 436 ? 18.447  -10.141 56.257 1.00 20.28  ? 638 PHE F CG  1 
ATOM   18110 C CD1 . PHE F 1 436 ? 18.463  -8.815  56.637 1.00 19.66  ? 638 PHE F CD1 1 
ATOM   18111 C CD2 . PHE F 1 436 ? 17.295  -10.656 55.692 1.00 19.94  ? 638 PHE F CD2 1 
ATOM   18112 C CE1 . PHE F 1 436 ? 17.348  -8.025  56.471 1.00 20.07  ? 638 PHE F CE1 1 
ATOM   18113 C CE2 . PHE F 1 436 ? 16.181  -9.870  55.522 1.00 20.20  ? 638 PHE F CE2 1 
ATOM   18114 C CZ  . PHE F 1 436 ? 16.207  -8.553  55.912 1.00 19.79  ? 638 PHE F CZ  1 
ATOM   18115 N N   . GLY F 1 437 ? 23.034  -11.289 55.541 1.00 28.30  ? 639 GLY F N   1 
ATOM   18116 C CA  . GLY F 1 437 ? 24.200  -12.081 55.888 1.00 28.69  ? 639 GLY F CA  1 
ATOM   18117 C C   . GLY F 1 437 ? 24.334  -12.200 57.396 1.00 29.77  ? 639 GLY F C   1 
ATOM   18118 O O   . GLY F 1 437 ? 24.100  -11.249 58.140 1.00 29.80  ? 639 GLY F O   1 
ATOM   18119 N N   . MET F 1 438 ? 24.732  -13.386 57.846 1.00 33.04  ? 640 MET F N   1 
ATOM   18120 C CA  . MET F 1 438 ? 24.760  -13.679 59.270 1.00 33.65  ? 640 MET F CA  1 
ATOM   18121 C C   . MET F 1 438 ? 25.902  -14.636 59.571 1.00 34.36  ? 640 MET F C   1 
ATOM   18122 O O   . MET F 1 438 ? 26.151  -15.573 58.810 1.00 34.39  ? 640 MET F O   1 
ATOM   18123 C CB  . MET F 1 438 ? 23.429  -14.287 59.734 1.00 33.38  ? 640 MET F CB  1 
ATOM   18124 C CG  . MET F 1 438 ? 22.247  -13.339 59.648 1.00 37.89  ? 640 MET F CG  1 
ATOM   18125 S SD  . MET F 1 438 ? 20.666  -14.086 60.064 1.00 42.36  ? 640 MET F SD  1 
ATOM   18126 C CE  . MET F 1 438 ? 20.874  -14.310 61.821 1.00 42.25  ? 640 MET F CE  1 
ATOM   18127 N N   . LYS F 1 439 ? 26.587  -14.399 60.689 1.00 36.40  ? 641 LYS F N   1 
ATOM   18128 C CA  . LYS F 1 439 ? 27.598  -15.338 61.154 1.00 38.34  ? 641 LYS F CA  1 
ATOM   18129 C C   . LYS F 1 439 ? 26.985  -16.563 61.811 1.00 38.29  ? 641 LYS F C   1 
ATOM   18130 O O   . LYS F 1 439 ? 27.651  -17.598 61.907 1.00 39.01  ? 641 LYS F O   1 
ATOM   18131 C CB  . LYS F 1 439 ? 28.553  -14.658 62.135 1.00 37.33  ? 641 LYS F CB  1 
ATOM   18132 C CG  . LYS F 1 439 ? 29.455  -13.617 61.504 1.00 43.23  ? 641 LYS F CG  1 
ATOM   18133 C CD  . LYS F 1 439 ? 30.532  -13.160 62.471 1.00 49.65  ? 641 LYS F CD  1 
ATOM   18134 C CE  . LYS F 1 439 ? 29.932  -12.439 63.664 1.00 52.02  ? 641 LYS F CE  1 
ATOM   18135 N NZ  . LYS F 1 439 ? 30.981  -11.897 64.570 1.00 52.77  ? 641 LYS F NZ  1 
ATOM   18136 N N   . HIS F 1 440 ? 25.737  -16.470 62.262 1.00 37.00  ? 642 HIS F N   1 
ATOM   18137 C CA  . HIS F 1 440 ? 25.015  -17.590 62.860 1.00 36.84  ? 642 HIS F CA  1 
ATOM   18138 C C   . HIS F 1 440 ? 23.600  -17.571 62.305 1.00 35.19  ? 642 HIS F C   1 
ATOM   18139 O O   . HIS F 1 440 ? 22.673  -17.053 62.942 1.00 35.30  ? 642 HIS F O   1 
ATOM   18140 C CB  . HIS F 1 440 ? 25.022  -17.506 64.386 1.00 37.15  ? 642 HIS F CB  1 
ATOM   18141 C CG  . HIS F 1 440 ? 26.395  -17.486 64.981 1.00 42.26  ? 642 HIS F CG  1 
ATOM   18142 N ND1 . HIS F 1 440 ? 27.236  -18.577 64.950 1.00 43.52  ? 642 HIS F ND1 1 
ATOM   18143 C CD2 . HIS F 1 440 ? 27.073  -16.507 65.623 1.00 43.35  ? 642 HIS F CD2 1 
ATOM   18144 C CE1 . HIS F 1 440 ? 28.374  -18.270 65.547 1.00 44.71  ? 642 HIS F CE1 1 
ATOM   18145 N NE2 . HIS F 1 440 ? 28.300  -17.019 65.964 1.00 45.93  ? 642 HIS F NE2 1 
ATOM   18146 N N   . PRO F 1 441 ? 23.398  -18.116 61.111 1.00 35.76  ? 643 PRO F N   1 
ATOM   18147 C CA  . PRO F 1 441 ? 22.065  -18.132 60.513 1.00 34.17  ? 643 PRO F CA  1 
ATOM   18148 C C   . PRO F 1 441 ? 21.184  -19.174 61.178 1.00 33.43  ? 643 PRO F C   1 
ATOM   18149 O O   . PRO F 1 441 ? 21.642  -19.900 62.073 1.00 33.51  ? 643 PRO F O   1 
ATOM   18150 C CB  . PRO F 1 441 ? 22.355  -18.490 59.049 1.00 33.00  ? 643 PRO F CB  1 
ATOM   18151 C CG  . PRO F 1 441 ? 23.599  -19.288 59.114 1.00 32.82  ? 643 PRO F CG  1 
ATOM   18152 C CD  . PRO F 1 441 ? 24.415  -18.675 60.207 1.00 32.78  ? 643 PRO F CD  1 
ATOM   18153 N N   . PRO F 1 442 ? 19.902  -19.275 60.780 1.00 32.62  ? 644 PRO F N   1 
ATOM   18154 C CA  . PRO F 1 442 ? 19.020  -20.342 61.266 1.00 32.11  ? 644 PRO F CA  1 
ATOM   18155 C C   . PRO F 1 442 ? 19.593  -21.742 61.070 1.00 32.40  ? 644 PRO F C   1 
ATOM   18156 O O   . PRO F 1 442 ? 20.287  -21.970 60.081 1.00 32.13  ? 644 PRO F O   1 
ATOM   18157 C CB  . PRO F 1 442 ? 17.762  -20.155 60.422 1.00 28.10  ? 644 PRO F CB  1 
ATOM   18158 C CG  . PRO F 1 442 ? 17.733  -18.712 60.137 1.00 28.45  ? 644 PRO F CG  1 
ATOM   18159 C CD  . PRO F 1 442 ? 19.154  -18.272 60.000 1.00 28.18  ? 644 PRO F CD  1 
ATOM   18160 N N   . LEU F 1 465 ? 25.274  -55.447 57.374 1.00 64.82  ? 667 LEU F N   1 
ATOM   18161 C CA  . LEU F 1 465 ? 23.884  -55.723 57.024 1.00 65.01  ? 667 LEU F CA  1 
ATOM   18162 C C   . LEU F 1 465 ? 23.384  -54.765 55.950 1.00 65.56  ? 667 LEU F C   1 
ATOM   18163 O O   . LEU F 1 465 ? 23.027  -53.629 56.239 1.00 65.65  ? 667 LEU F O   1 
ATOM   18164 C CB  . LEU F 1 465 ? 22.991  -55.638 58.262 1.00 67.77  ? 667 LEU F CB  1 
ATOM   18165 C CG  . LEU F 1 465 ? 23.247  -56.690 59.341 1.00 67.12  ? 667 LEU F CG  1 
ATOM   18166 C CD1 . LEU F 1 465 ? 22.398  -56.425 60.570 1.00 67.91  ? 667 LEU F CD1 1 
ATOM   18167 C CD2 . LEU F 1 465 ? 22.979  -58.080 58.797 1.00 66.70  ? 667 LEU F CD2 1 
ATOM   18168 N N   . ASN F 1 466 ? 23.374  -55.232 54.705 1.00 67.31  ? 668 ASN F N   1 
ATOM   18169 C CA  . ASN F 1 466 ? 22.964  -54.425 53.566 1.00 68.79  ? 668 ASN F CA  1 
ATOM   18170 C C   . ASN F 1 466 ? 21.516  -54.650 53.145 1.00 67.90  ? 668 ASN F C   1 
ATOM   18171 O O   . ASN F 1 466 ? 21.072  -54.043 52.166 1.00 68.55  ? 668 ASN F O   1 
ATOM   18172 C CB  . ASN F 1 466 ? 23.904  -54.682 52.381 1.00 65.46  ? 668 ASN F CB  1 
ATOM   18173 C CG  . ASN F 1 466 ? 23.944  -56.143 51.961 1.00 70.82  ? 668 ASN F CG  1 
ATOM   18174 O OD1 . ASN F 1 466 ? 22.950  -56.862 52.044 1.00 74.36  ? 668 ASN F OD1 1 
ATOM   18175 N ND2 . ASN F 1 466 ? 25.109  -56.589 51.509 1.00 74.16  ? 668 ASN F ND2 1 
ATOM   18176 N N   . SER F 1 467 ? 20.773  -55.505 53.844 1.00 69.74  ? 669 SER F N   1 
ATOM   18177 C CA  . SER F 1 467 ? 19.397  -55.829 53.484 1.00 67.93  ? 669 SER F CA  1 
ATOM   18178 C C   . SER F 1 467 ? 18.451  -55.102 54.427 1.00 66.70  ? 669 SER F C   1 
ATOM   18179 O O   . SER F 1 467 ? 18.466  -55.349 55.638 1.00 65.56  ? 669 SER F O   1 
ATOM   18180 C CB  . SER F 1 467 ? 19.155  -57.338 53.538 1.00 68.08  ? 669 SER F CB  1 
ATOM   18181 O OG  . SER F 1 467 ? 17.811  -57.646 53.219 1.00 70.28  ? 669 SER F OG  1 
ATOM   18182 N N   . PHE F 1 468 ? 17.623  -54.219 53.873 1.00 63.78  ? 670 PHE F N   1 
ATOM   18183 C CA  . PHE F 1 468 ? 16.707  -53.409 54.660 1.00 62.68  ? 670 PHE F CA  1 
ATOM   18184 C C   . PHE F 1 468 ? 15.314  -53.456 54.051 1.00 62.40  ? 670 PHE F C   1 
ATOM   18185 O O   . PHE F 1 468 ? 15.117  -53.906 52.920 1.00 63.60  ? 670 PHE F O   1 
ATOM   18186 C CB  . PHE F 1 468 ? 17.177  -51.953 54.753 1.00 58.40  ? 670 PHE F CB  1 
ATOM   18187 C CG  . PHE F 1 468 ? 18.493  -51.784 55.450 1.00 59.42  ? 670 PHE F CG  1 
ATOM   18188 C CD1 . PHE F 1 468 ? 18.558  -51.723 56.829 1.00 60.36  ? 670 PHE F CD1 1 
ATOM   18189 C CD2 . PHE F 1 468 ? 19.666  -51.686 54.726 1.00 59.02  ? 670 PHE F CD2 1 
ATOM   18190 C CE1 . PHE F 1 468 ? 19.767  -51.569 57.472 1.00 61.72  ? 670 PHE F CE1 1 
ATOM   18191 C CE2 . PHE F 1 468 ? 20.875  -51.532 55.364 1.00 60.16  ? 670 PHE F CE2 1 
ATOM   18192 C CZ  . PHE F 1 468 ? 20.924  -51.472 56.739 1.00 60.90  ? 670 PHE F CZ  1 
ATOM   18193 N N   . ILE F 1 469 ? 14.346  -52.976 54.824 1.00 63.14  ? 671 ILE F N   1 
ATOM   18194 C CA  . ILE F 1 469 ? 12.960  -52.909 54.377 1.00 62.66  ? 671 ILE F CA  1 
ATOM   18195 C C   . ILE F 1 469 ? 12.736  -51.590 53.651 1.00 62.71  ? 671 ILE F C   1 
ATOM   18196 O O   . ILE F 1 469 ? 13.156  -50.529 54.127 1.00 62.89  ? 671 ILE F O   1 
ATOM   18197 C CB  . ILE F 1 469 ? 12.001  -53.051 55.570 1.00 61.95  ? 671 ILE F CB  1 
ATOM   18198 C CG1 . ILE F 1 469 ? 12.132  -54.434 56.205 1.00 61.67  ? 671 ILE F CG1 1 
ATOM   18199 C CG2 . ILE F 1 469 ? 10.566  -52.794 55.142 1.00 61.37  ? 671 ILE F CG2 1 
ATOM   18200 C CD1 . ILE F 1 469 ? 11.401  -54.570 57.519 1.00 65.33  ? 671 ILE F CD1 1 
ATOM   18201 N N   . THR F 1 470 ? 12.077  -51.651 52.495 1.00 63.84  ? 672 THR F N   1 
ATOM   18202 C CA  . THR F 1 470 ? 11.674  -50.433 51.807 1.00 64.90  ? 672 THR F CA  1 
ATOM   18203 C C   . THR F 1 470 ? 10.728  -49.640 52.695 1.00 63.81  ? 672 THR F C   1 
ATOM   18204 O O   . THR F 1 470 ? 9.709   -50.163 53.154 1.00 62.59  ? 672 THR F O   1 
ATOM   18205 C CB  . THR F 1 470 ? 11.000  -50.764 50.479 1.00 62.42  ? 672 THR F CB  1 
ATOM   18206 O OG1 . THR F 1 470 ? 11.930  -51.437 49.622 1.00 67.08  ? 672 THR F OG1 1 
ATOM   18207 C CG2 . THR F 1 470 ? 10.515  -49.494 49.799 1.00 62.79  ? 672 THR F CG2 1 
ATOM   18208 N N   . GLN F 1 471 ? 11.061  -48.378 52.941 1.00 57.81  ? 673 GLN F N   1 
ATOM   18209 C CA  . GLN F 1 471 ? 10.376  -47.642 53.990 1.00 57.07  ? 673 GLN F CA  1 
ATOM   18210 C C   . GLN F 1 471 ? 10.466  -46.152 53.692 1.00 56.24  ? 673 GLN F C   1 
ATOM   18211 O O   . GLN F 1 471 ? 11.405  -45.697 53.035 1.00 58.09  ? 673 GLN F O   1 
ATOM   18212 C CB  . GLN F 1 471 ? 11.006  -47.987 55.342 1.00 54.68  ? 673 GLN F CB  1 
ATOM   18213 C CG  . GLN F 1 471 ? 10.263  -47.554 56.576 1.00 59.00  ? 673 GLN F CG  1 
ATOM   18214 C CD  . GLN F 1 471 ? 10.916  -48.117 57.821 1.00 62.32  ? 673 GLN F CD  1 
ATOM   18215 O OE1 . GLN F 1 471 ? 11.897  -48.853 57.737 1.00 64.84  ? 673 GLN F OE1 1 
ATOM   18216 N NE2 . GLN F 1 471 ? 10.367  -47.793 58.977 1.00 61.82  ? 673 GLN F NE2 1 
ATOM   18217 N N   . TYR F 1 472 ? 9.482   -45.397 54.179 1.00 51.28  ? 674 TYR F N   1 
ATOM   18218 C CA  . TYR F 1 472 ? 9.531   -43.947 54.070 1.00 49.98  ? 674 TYR F CA  1 
ATOM   18219 C C   . TYR F 1 472 ? 8.651   -43.342 55.152 1.00 48.96  ? 674 TYR F C   1 
ATOM   18220 O O   . TYR F 1 472 ? 7.843   -44.030 55.780 1.00 48.74  ? 674 TYR F O   1 
ATOM   18221 C CB  . TYR F 1 472 ? 9.102   -43.449 52.684 1.00 49.72  ? 674 TYR F CB  1 
ATOM   18222 C CG  . TYR F 1 472 ? 7.637   -43.610 52.373 1.00 49.92  ? 674 TYR F CG  1 
ATOM   18223 C CD1 . TYR F 1 472 ? 6.737   -42.590 52.646 1.00 50.19  ? 674 TYR F CD1 1 
ATOM   18224 C CD2 . TYR F 1 472 ? 7.153   -44.773 51.798 1.00 50.53  ? 674 TYR F CD2 1 
ATOM   18225 C CE1 . TYR F 1 472 ? 5.396   -42.727 52.362 1.00 51.11  ? 674 TYR F CE1 1 
ATOM   18226 C CE2 . TYR F 1 472 ? 5.811   -44.921 51.515 1.00 51.14  ? 674 TYR F CE2 1 
ATOM   18227 C CZ  . TYR F 1 472 ? 4.939   -43.893 51.794 1.00 51.96  ? 674 TYR F CZ  1 
ATOM   18228 O OH  . TYR F 1 472 ? 3.604   -44.035 51.509 1.00 52.13  ? 674 TYR F OH  1 
ATOM   18229 N N   . SER F 1 473 ? 8.829   -42.044 55.371 1.00 43.30  ? 675 SER F N   1 
ATOM   18230 C CA  . SER F 1 473 ? 8.107   -41.318 56.402 1.00 43.22  ? 675 SER F CA  1 
ATOM   18231 C C   . SER F 1 473 ? 7.384   -40.126 55.788 1.00 42.98  ? 675 SER F C   1 
ATOM   18232 O O   . SER F 1 473 ? 7.642   -39.727 54.650 1.00 43.20  ? 675 SER F O   1 
ATOM   18233 C CB  . SER F 1 473 ? 9.053   -40.861 57.522 1.00 42.29  ? 675 SER F CB  1 
ATOM   18234 O OG  . SER F 1 473 ? 10.051  -39.988 57.026 1.00 45.73  ? 675 SER F OG  1 
ATOM   18235 N N   . THR F 1 474 ? 6.443   -39.579 56.553 1.00 41.66  ? 676 THR F N   1 
ATOM   18236 C CA  . THR F 1 474 ? 5.744   -38.359 56.180 1.00 42.04  ? 676 THR F CA  1 
ATOM   18237 C C   . THR F 1 474 ? 5.201   -37.712 57.443 1.00 40.62  ? 676 THR F C   1 
ATOM   18238 O O   . THR F 1 474 ? 5.064   -38.360 58.483 1.00 41.68  ? 676 THR F O   1 
ATOM   18239 C CB  . THR F 1 474 ? 4.618   -38.629 55.178 1.00 44.55  ? 676 THR F CB  1 
ATOM   18240 O OG1 . THR F 1 474 ? 4.083   -37.382 54.720 1.00 47.87  ? 676 THR F OG1 1 
ATOM   18241 C CG2 . THR F 1 474 ? 3.512   -39.441 55.817 1.00 44.11  ? 676 THR F CG2 1 
ATOM   18242 N N   . GLY F 1 475 ? 4.888   -36.426 57.347 1.00 39.96  ? 677 GLY F N   1 
ATOM   18243 C CA  . GLY F 1 475 ? 4.510   -35.686 58.534 1.00 38.29  ? 677 GLY F CA  1 
ATOM   18244 C C   . GLY F 1 475 ? 4.148   -34.252 58.227 1.00 38.31  ? 677 GLY F C   1 
ATOM   18245 O O   . GLY F 1 475 ? 3.786   -33.912 57.099 1.00 38.29  ? 677 GLY F O   1 
ATOM   18246 N N   . GLN F 1 476 ? 4.234   -33.416 59.260 1.00 35.41  ? 678 GLN F N   1 
ATOM   18247 C CA  . GLN F 1 476 ? 3.910   -32.000 59.170 1.00 35.96  ? 678 GLN F CA  1 
ATOM   18248 C C   . GLN F 1 476 ? 5.041   -31.176 59.770 1.00 36.79  ? 678 GLN F C   1 
ATOM   18249 O O   . GLN F 1 476 ? 5.675   -31.592 60.743 1.00 36.23  ? 678 GLN F O   1 
ATOM   18250 C CB  . GLN F 1 476 ? 2.603   -31.685 59.901 1.00 31.93  ? 678 GLN F CB  1 
ATOM   18251 C CG  . GLN F 1 476 ? 1.399   -32.462 59.400 1.00 34.00  ? 678 GLN F CG  1 
ATOM   18252 C CD  . GLN F 1 476 ? 1.149   -32.259 57.929 1.00 35.81  ? 678 GLN F CD  1 
ATOM   18253 O OE1 . GLN F 1 476 ? 1.318   -31.161 57.406 1.00 37.19  ? 678 GLN F OE1 1 
ATOM   18254 N NE2 . GLN F 1 476 ? 0.743   -33.322 57.247 1.00 35.49  ? 678 GLN F NE2 1 
ATOM   18255 N N   . VAL F 1 477 ? 5.285   -30.005 59.188 1.00 34.77  ? 679 VAL F N   1 
ATOM   18256 C CA  . VAL F 1 477 ? 6.306   -29.074 59.654 1.00 35.12  ? 679 VAL F CA  1 
ATOM   18257 C C   . VAL F 1 477 ? 5.699   -27.683 59.731 1.00 36.25  ? 679 VAL F C   1 
ATOM   18258 O O   . VAL F 1 477 ? 5.048   -27.232 58.784 1.00 36.29  ? 679 VAL F O   1 
ATOM   18259 C CB  . VAL F 1 477 ? 7.540   -29.069 58.731 1.00 32.74  ? 679 VAL F CB  1 
ATOM   18260 C CG1 . VAL F 1 477 ? 8.437   -27.910 59.066 1.00 34.15  ? 679 VAL F CG1 1 
ATOM   18261 C CG2 . VAL F 1 477 ? 8.308   -30.341 58.903 1.00 34.30  ? 679 VAL F CG2 1 
ATOM   18262 N N   . SER F 1 478 ? 5.922   -27.001 60.850 1.00 31.90  ? 680 SER F N   1 
ATOM   18263 C CA  . SER F 1 478 ? 5.453   -25.637 61.036 1.00 33.27  ? 680 SER F CA  1 
ATOM   18264 C C   . SER F 1 478 ? 6.603   -24.752 61.490 1.00 33.10  ? 680 SER F C   1 
ATOM   18265 O O   . SER F 1 478 ? 7.211   -24.995 62.536 1.00 33.83  ? 680 SER F O   1 
ATOM   18266 C CB  . SER F 1 478 ? 4.313   -25.572 62.054 1.00 35.94  ? 680 SER F CB  1 
ATOM   18267 O OG  . SER F 1 478 ? 4.760   -25.954 63.340 1.00 41.71  ? 680 SER F OG  1 
ATOM   18268 N N   . VAL F 1 479 ? 6.891   -23.720 60.702 1.00 29.80  ? 681 VAL F N   1 
ATOM   18269 C CA  . VAL F 1 479 ? 7.934   -22.753 61.012 1.00 29.70  ? 681 VAL F CA  1 
ATOM   18270 C C   . VAL F 1 479 ? 7.286   -21.393 61.233 1.00 30.24  ? 681 VAL F C   1 
ATOM   18271 O O   . VAL F 1 479 ? 6.388   -20.990 60.486 1.00 29.87  ? 681 VAL F O   1 
ATOM   18272 C CB  . VAL F 1 479 ? 9.007   -22.692 59.903 1.00 26.33  ? 681 VAL F CB  1 
ATOM   18273 C CG1 . VAL F 1 479 ? 8.393   -22.297 58.571 1.00 24.87  ? 681 VAL F CG1 1 
ATOM   18274 C CG2 . VAL F 1 479 ? 10.111  -21.732 60.288 1.00 28.63  ? 681 VAL F CG2 1 
ATOM   18275 N N   . GLU F 1 480 ? 7.722   -20.701 62.282 1.00 29.71  ? 682 GLU F N   1 
ATOM   18276 C CA  . GLU F 1 480 ? 7.162   -19.417 62.677 1.00 30.89  ? 682 GLU F CA  1 
ATOM   18277 C C   . GLU F 1 480 ? 8.288   -18.414 62.856 1.00 29.84  ? 682 GLU F C   1 
ATOM   18278 O O   . GLU F 1 480 ? 9.117   -18.565 63.758 1.00 30.95  ? 682 GLU F O   1 
ATOM   18279 C CB  . GLU F 1 480 ? 6.360   -19.552 63.972 1.00 29.70  ? 682 GLU F CB  1 
ATOM   18280 C CG  . GLU F 1 480 ? 5.679   -18.281 64.429 1.00 38.58  ? 682 GLU F CG  1 
ATOM   18281 C CD  . GLU F 1 480 ? 4.888   -18.479 65.707 1.00 45.10  ? 682 GLU F CD  1 
ATOM   18282 O OE1 . GLU F 1 480 ? 4.914   -19.601 66.254 1.00 48.65  ? 682 GLU F OE1 1 
ATOM   18283 O OE2 . GLU F 1 480 ? 4.242   -17.516 66.167 1.00 49.37  ? 682 GLU F OE2 1 
ATOM   18284 N N   . ILE F 1 481 ? 8.312   -17.388 62.010 1.00 29.06  ? 683 ILE F N   1 
ATOM   18285 C CA  . ILE F 1 481 ? 9.342   -16.358 62.051 1.00 27.46  ? 683 ILE F CA  1 
ATOM   18286 C C   . ILE F 1 481 ? 8.689   -15.043 62.445 1.00 28.95  ? 683 ILE F C   1 
ATOM   18287 O O   . ILE F 1 481 ? 7.608   -14.710 61.949 1.00 29.46  ? 683 ILE F O   1 
ATOM   18288 C CB  . ILE F 1 481 ? 10.069  -16.210 60.702 1.00 25.50  ? 683 ILE F CB  1 
ATOM   18289 C CG1 . ILE F 1 481 ? 10.788  -17.502 60.336 1.00 24.87  ? 683 ILE F CG1 1 
ATOM   18290 C CG2 . ILE F 1 481 ? 11.078  -15.083 60.764 1.00 22.91  ? 683 ILE F CG2 1 
ATOM   18291 C CD1 . ILE F 1 481 ? 11.346  -17.492 58.945 1.00 24.36  ? 683 ILE F CD1 1 
ATOM   18292 N N   . GLU F 1 482 ? 9.345   -14.302 63.330 1.00 28.15  ? 684 GLU F N   1 
ATOM   18293 C CA  . GLU F 1 482 ? 8.898   -12.979 63.735 1.00 29.63  ? 684 GLU F CA  1 
ATOM   18294 C C   . GLU F 1 482 ? 9.722   -11.929 63.004 1.00 28.48  ? 684 GLU F C   1 
ATOM   18295 O O   . GLU F 1 482 ? 10.955  -11.958 63.051 1.00 28.64  ? 684 GLU F O   1 
ATOM   18296 C CB  . GLU F 1 482 ? 9.020   -12.807 65.247 1.00 30.36  ? 684 GLU F CB  1 
ATOM   18297 C CG  . GLU F 1 482 ? 8.506   -11.481 65.762 1.00 39.94  ? 684 GLU F CG  1 
ATOM   18298 C CD  . GLU F 1 482 ? 8.534   -11.404 67.272 1.00 46.65  ? 684 GLU F CD  1 
ATOM   18299 O OE1 . GLU F 1 482 ? 8.966   -12.388 67.908 1.00 49.70  ? 684 GLU F OE1 1 
ATOM   18300 O OE2 . GLU F 1 482 ? 8.126   -10.363 67.825 1.00 50.53  ? 684 GLU F OE2 1 
ATOM   18301 N N   . TRP F 1 483 ? 9.041   -11.015 62.323 1.00 26.44  ? 685 TRP F N   1 
ATOM   18302 C CA  . TRP F 1 483 ? 9.680   -9.999  61.502 1.00 26.09  ? 685 TRP F CA  1 
ATOM   18303 C C   . TRP F 1 483 ? 9.493   -8.633  62.144 1.00 27.03  ? 685 TRP F C   1 
ATOM   18304 O O   . TRP F 1 483 ? 8.443   -8.355  62.729 1.00 26.94  ? 685 TRP F O   1 
ATOM   18305 C CB  . TRP F 1 483 ? 9.087   -9.990  60.093 1.00 21.97  ? 685 TRP F CB  1 
ATOM   18306 C CG  . TRP F 1 483 ? 9.302   -11.256 59.336 1.00 20.97  ? 685 TRP F CG  1 
ATOM   18307 C CD1 . TRP F 1 483 ? 8.472   -12.332 59.299 1.00 20.90  ? 685 TRP F CD1 1 
ATOM   18308 C CD2 . TRP F 1 483 ? 10.405  -11.570 58.483 1.00 20.28  ? 685 TRP F CD2 1 
ATOM   18309 N NE1 . TRP F 1 483 ? 8.996   -13.307 58.490 1.00 19.97  ? 685 TRP F NE1 1 
ATOM   18310 C CE2 . TRP F 1 483 ? 10.183  -12.863 57.975 1.00 20.57  ? 685 TRP F CE2 1 
ATOM   18311 C CE3 . TRP F 1 483 ? 11.561  -10.888 58.105 1.00 20.47  ? 685 TRP F CE3 1 
ATOM   18312 C CZ2 . TRP F 1 483 ? 11.072  -13.485 57.110 1.00 20.80  ? 685 TRP F CZ2 1 
ATOM   18313 C CZ3 . TRP F 1 483 ? 12.440  -11.506 57.246 1.00 20.76  ? 685 TRP F CZ3 1 
ATOM   18314 C CH2 . TRP F 1 483 ? 12.193  -12.792 56.758 1.00 21.40  ? 685 TRP F CH2 1 
ATOM   18315 N N   . GLU F 1 484 ? 10.509  -7.785  62.038 1.00 22.09  ? 686 GLU F N   1 
ATOM   18316 C CA  . GLU F 1 484 ? 10.420  -6.406  62.498 1.00 23.78  ? 686 GLU F CA  1 
ATOM   18317 C C   . GLU F 1 484 ? 10.313  -5.482  61.294 1.00 22.44  ? 686 GLU F C   1 
ATOM   18318 O O   . GLU F 1 484 ? 10.903  -5.747  60.245 1.00 21.38  ? 686 GLU F O   1 
ATOM   18319 C CB  . GLU F 1 484 ? 11.631  -6.025  63.350 1.00 20.76  ? 686 GLU F CB  1 
ATOM   18320 C CG  . GLU F 1 484 ? 11.552  -4.624  63.935 1.00 29.49  ? 686 GLU F CG  1 
ATOM   18321 C CD  . GLU F 1 484 ? 12.735  -4.283  64.814 1.00 35.33  ? 686 GLU F CD  1 
ATOM   18322 O OE1 . GLU F 1 484 ? 13.643  -5.126  64.949 1.00 37.13  ? 686 GLU F OE1 1 
ATOM   18323 O OE2 . GLU F 1 484 ? 12.760  -3.167  65.371 1.00 37.10  ? 686 GLU F OE2 1 
ATOM   18324 N N   . LEU F 1 485 ? 9.569   -4.394  61.454 1.00 21.08  ? 687 LEU F N   1 
ATOM   18325 C CA  . LEU F 1 485 ? 9.254   -3.488  60.362 1.00 21.75  ? 687 LEU F CA  1 
ATOM   18326 C C   . LEU F 1 485 ? 9.825   -2.106  60.638 1.00 24.63  ? 687 LEU F C   1 
ATOM   18327 O O   . LEU F 1 485 ? 10.115  -1.752  61.782 1.00 25.33  ? 687 LEU F O   1 
ATOM   18328 C CB  . LEU F 1 485 ? 7.745   -3.369  60.169 1.00 22.33  ? 687 LEU F CB  1 
ATOM   18329 C CG  . LEU F 1 485 ? 6.992   -4.665  59.903 1.00 20.24  ? 687 LEU F CG  1 
ATOM   18330 C CD1 . LEU F 1 485 ? 5.506   -4.382  59.837 1.00 19.17  ? 687 LEU F CD1 1 
ATOM   18331 C CD2 . LEU F 1 485 ? 7.488   -5.318  58.637 1.00 19.58  ? 687 LEU F CD2 1 
ATOM   18332 N N   . GLN F 1 486 ? 9.983   -1.327  59.573 1.00 16.53  ? 688 GLN F N   1 
ATOM   18333 C CA  . GLN F 1 486 ? 10.338  0.084   59.670 1.00 19.84  ? 688 GLN F CA  1 
ATOM   18334 C C   . GLN F 1 486 ? 9.312   0.874   58.869 1.00 21.90  ? 688 GLN F C   1 
ATOM   18335 O O   . GLN F 1 486 ? 9.240   0.742   57.644 1.00 22.69  ? 688 GLN F O   1 
ATOM   18336 C CB  . GLN F 1 486 ? 11.753  0.331   59.159 1.00 20.60  ? 688 GLN F CB  1 
ATOM   18337 C CG  . GLN F 1 486 ? 12.242  1.743   59.386 1.00 26.20  ? 688 GLN F CG  1 
ATOM   18338 C CD  . GLN F 1 486 ? 13.693  1.909   59.011 1.00 31.29  ? 688 GLN F CD  1 
ATOM   18339 O OE1 . GLN F 1 486 ? 14.358  0.947   58.632 1.00 33.89  ? 688 GLN F OE1 1 
ATOM   18340 N NE2 . GLN F 1 486 ? 14.199  3.130   59.120 1.00 32.48  ? 688 GLN F NE2 1 
ATOM   18341 N N   . LYS F 1 487 ? 8.524   1.693   59.557 1.00 20.64  ? 689 LYS F N   1 
ATOM   18342 C CA  . LYS F 1 487 ? 7.408   2.382   58.927 1.00 23.39  ? 689 LYS F CA  1 
ATOM   18343 C C   . LYS F 1 487 ? 7.888   3.522   58.040 1.00 23.89  ? 689 LYS F C   1 
ATOM   18344 O O   . LYS F 1 487 ? 8.921   4.147   58.291 1.00 22.48  ? 689 LYS F O   1 
ATOM   18345 C CB  . LYS F 1 487 ? 6.445   2.918   59.985 1.00 22.84  ? 689 LYS F CB  1 
ATOM   18346 C CG  . LYS F 1 487 ? 5.872   1.832   60.884 1.00 27.84  ? 689 LYS F CG  1 
ATOM   18347 C CD  . LYS F 1 487 ? 5.106   0.812   60.066 1.00 32.40  ? 689 LYS F CD  1 
ATOM   18348 C CE  . LYS F 1 487 ? 4.474   -0.247  60.951 1.00 35.15  ? 689 LYS F CE  1 
ATOM   18349 N NZ  . LYS F 1 487 ? 3.739   -1.251  60.136 1.00 34.48  ? 689 LYS F NZ  1 
ATOM   18350 N N   . GLU F 1 488 ? 7.116   3.784   56.989 1.00 21.81  ? 690 GLU F N   1 
ATOM   18351 C CA  . GLU F 1 488 ? 7.416   4.848   56.040 1.00 23.80  ? 690 GLU F CA  1 
ATOM   18352 C C   . GLU F 1 488 ? 7.013   6.196   56.629 1.00 22.72  ? 690 GLU F C   1 
ATOM   18353 O O   . GLU F 1 488 ? 5.835   6.431   56.914 1.00 23.50  ? 690 GLU F O   1 
ATOM   18354 C CB  . GLU F 1 488 ? 6.689   4.559   54.726 1.00 15.04  ? 690 GLU F CB  1 
ATOM   18355 C CG  . GLU F 1 488 ? 6.700   5.657   53.680 1.00 22.93  ? 690 GLU F CG  1 
ATOM   18356 C CD  . GLU F 1 488 ? 5.530   6.609   53.843 1.00 28.06  ? 690 GLU F CD  1 
ATOM   18357 O OE1 . GLU F 1 488 ? 4.508   6.199   54.435 1.00 30.68  ? 690 GLU F OE1 1 
ATOM   18358 O OE2 . GLU F 1 488 ? 5.622   7.757   53.369 1.00 28.76  ? 690 GLU F OE2 1 
ATOM   18359 N N   . ASN F 1 489 ? 7.998   7.071   56.827 1.00 25.10  ? 691 ASN F N   1 
ATOM   18360 C CA  . ASN F 1 489 ? 7.806   8.376   57.447 1.00 23.49  ? 691 ASN F CA  1 
ATOM   18361 C C   . ASN F 1 489 ? 7.756   9.523   56.439 1.00 21.60  ? 691 ASN F C   1 
ATOM   18362 O O   . ASN F 1 489 ? 7.678   10.685  56.847 1.00 19.97  ? 691 ASN F O   1 
ATOM   18363 C CB  . ASN F 1 489 ? 8.908   8.613   58.482 1.00 25.41  ? 691 ASN F CB  1 
ATOM   18364 C CG  . ASN F 1 489 ? 8.590   9.744   59.437 1.00 28.97  ? 691 ASN F CG  1 
ATOM   18365 O OD1 . ASN F 1 489 ? 7.428   10.028  59.723 1.00 30.39  ? 691 ASN F OD1 1 
ATOM   18366 N ND2 . ASN F 1 489 ? 9.631   10.394  59.943 1.00 29.30  ? 691 ASN F ND2 1 
ATOM   18367 N N   . SER F 1 490 ? 7.811   9.227   55.143 1.00 22.11  ? 692 SER F N   1 
ATOM   18368 C CA  . SER F 1 490 ? 8.057   10.247  54.130 1.00 19.56  ? 692 SER F CA  1 
ATOM   18369 C C   . SER F 1 490 ? 7.026   11.369  54.167 1.00 17.42  ? 692 SER F C   1 
ATOM   18370 O O   . SER F 1 490 ? 5.850   11.163  54.477 1.00 17.83  ? 692 SER F O   1 
ATOM   18371 C CB  . SER F 1 490 ? 8.063   9.620   52.739 1.00 19.27  ? 692 SER F CB  1 
ATOM   18372 O OG  . SER F 1 490 ? 8.228   10.612  51.744 1.00 20.17  ? 692 SER F OG  1 
ATOM   18373 N N   . LYS F 1 491 ? 7.494   12.576  53.848 1.00 18.73  ? 693 LYS F N   1 
ATOM   18374 C CA  . LYS F 1 491 ? 6.662   13.761  53.693 1.00 15.33  ? 693 LYS F CA  1 
ATOM   18375 C C   . LYS F 1 491 ? 6.272   14.029  52.250 1.00 13.15  ? 693 LYS F C   1 
ATOM   18376 O O   . LYS F 1 491 ? 5.724   15.096  51.961 1.00 12.08  ? 693 LYS F O   1 
ATOM   18377 C CB  . LYS F 1 491 ? 7.366   14.987  54.265 1.00 20.40  ? 693 LYS F CB  1 
ATOM   18378 C CG  . LYS F 1 491 ? 7.583   14.924  55.746 1.00 21.31  ? 693 LYS F CG  1 
ATOM   18379 C CD  . LYS F 1 491 ? 6.270   14.834  56.488 1.00 22.96  ? 693 LYS F CD  1 
ATOM   18380 C CE  . LYS F 1 491 ? 5.551   16.164  56.458 1.00 24.64  ? 693 LYS F CE  1 
ATOM   18381 N NZ  . LYS F 1 491 ? 4.325   16.150  57.289 1.00 25.37  ? 693 LYS F NZ  1 
ATOM   18382 N N   . ARG F 1 492 ? 6.582   13.115  51.338 1.00 13.89  ? 694 ARG F N   1 
ATOM   18383 C CA  . ARG F 1 492 ? 6.255   13.301  49.930 1.00 12.22  ? 694 ARG F CA  1 
ATOM   18384 C C   . ARG F 1 492 ? 4.785   13.664  49.754 1.00 11.93  ? 694 ARG F C   1 
ATOM   18385 O O   . ARG F 1 492 ? 3.906   13.032  50.343 1.00 12.15  ? 694 ARG F O   1 
ATOM   18386 C CB  . ARG F 1 492 ? 6.583   12.027  49.160 1.00 10.27  ? 694 ARG F CB  1 
ATOM   18387 C CG  . ARG F 1 492 ? 6.253   12.113  47.702 1.00 10.69  ? 694 ARG F CG  1 
ATOM   18388 C CD  . ARG F 1 492 ? 6.639   10.856  46.975 1.00 11.62  ? 694 ARG F CD  1 
ATOM   18389 N NE  . ARG F 1 492 ? 6.279   10.906  45.567 1.00 12.73  ? 694 ARG F NE  1 
ATOM   18390 C CZ  . ARG F 1 492 ? 6.653   10.001  44.674 1.00 14.11  ? 694 ARG F CZ  1 
ATOM   18391 N NH1 . ARG F 1 492 ? 7.404   8.980   45.047 1.00 13.48  ? 694 ARG F NH1 1 
ATOM   18392 N NH2 . ARG F 1 492 ? 6.281   10.119  43.411 1.00 13.70  ? 694 ARG F NH2 1 
ATOM   18393 N N   . TRP F 1 493 ? 4.523   14.698  48.952 1.00 11.12  ? 695 TRP F N   1 
ATOM   18394 C CA  . TRP F 1 493 ? 3.152   15.162  48.763 1.00 9.87   ? 695 TRP F CA  1 
ATOM   18395 C C   . TRP F 1 493 ? 2.388   14.273  47.793 1.00 10.79  ? 695 TRP F C   1 
ATOM   18396 O O   . TRP F 1 493 ? 1.270   13.837  48.084 1.00 10.43  ? 695 TRP F O   1 
ATOM   18397 C CB  . TRP F 1 493 ? 3.150   16.602  48.260 1.00 12.61  ? 695 TRP F CB  1 
ATOM   18398 C CG  . TRP F 1 493 ? 1.781   17.137  48.020 1.00 12.89  ? 695 TRP F CG  1 
ATOM   18399 C CD1 . TRP F 1 493 ? 1.141   17.243  46.823 1.00 12.70  ? 695 TRP F CD1 1 
ATOM   18400 C CD2 . TRP F 1 493 ? 0.884   17.659  49.001 1.00 13.71  ? 695 TRP F CD2 1 
ATOM   18401 N NE1 . TRP F 1 493 ? -0.103  17.786  46.998 1.00 12.39  ? 695 TRP F NE1 1 
ATOM   18402 C CE2 . TRP F 1 493 ? -0.284  18.057  48.327 1.00 13.56  ? 695 TRP F CE2 1 
ATOM   18403 C CE3 . TRP F 1 493 ? 0.954   17.829  50.385 1.00 13.20  ? 695 TRP F CE3 1 
ATOM   18404 C CZ2 . TRP F 1 493 ? -1.371  18.607  48.986 1.00 13.87  ? 695 TRP F CZ2 1 
ATOM   18405 C CZ3 . TRP F 1 493 ? -0.122  18.381  51.034 1.00 12.57  ? 695 TRP F CZ3 1 
ATOM   18406 C CH2 . TRP F 1 493 ? -1.272  18.759  50.337 1.00 14.22  ? 695 TRP F CH2 1 
ATOM   18407 N N   . ASN F 1 494 ? 2.973   13.993  46.632 1.00 10.49  ? 696 ASN F N   1 
ATOM   18408 C CA  . ASN F 1 494 ? 2.256   13.286  45.585 1.00 10.70  ? 696 ASN F CA  1 
ATOM   18409 C C   . ASN F 1 494 ? 2.290   11.779  45.831 1.00 11.47  ? 696 ASN F C   1 
ATOM   18410 O O   . ASN F 1 494 ? 3.122   11.284  46.593 1.00 12.29  ? 696 ASN F O   1 
ATOM   18411 C CB  . ASN F 1 494 ? 2.846   13.636  44.219 1.00 11.55  ? 696 ASN F CB  1 
ATOM   18412 C CG  . ASN F 1 494 ? 4.285   13.221  44.080 1.00 10.51  ? 696 ASN F CG  1 
ATOM   18413 O OD1 . ASN F 1 494 ? 4.969   12.989  45.065 1.00 11.17  ? 696 ASN F OD1 1 
ATOM   18414 N ND2 . ASN F 1 494 ? 4.750   13.104  42.846 1.00 10.44  ? 696 ASN F ND2 1 
ATOM   18415 N N   . PRO F 1 495 ? 1.380   11.027  45.209 1.00 9.80   ? 697 PRO F N   1 
ATOM   18416 C CA  . PRO F 1 495 ? 1.281   9.596   45.512 1.00 10.39  ? 697 PRO F CA  1 
ATOM   18417 C C   . PRO F 1 495 ? 2.526   8.812   45.116 1.00 11.34  ? 697 PRO F C   1 
ATOM   18418 O O   . PRO F 1 495 ? 3.197   9.123   44.132 1.00 11.01  ? 697 PRO F O   1 
ATOM   18419 C CB  . PRO F 1 495 ? 0.057   9.155   44.702 1.00 9.97   ? 697 PRO F CB  1 
ATOM   18420 C CG  . PRO F 1 495 ? -0.058  10.149  43.626 1.00 11.83  ? 697 PRO F CG  1 
ATOM   18421 C CD  . PRO F 1 495 ? 0.330   11.438  44.262 1.00 10.01  ? 697 PRO F CD  1 
ATOM   18422 N N   . GLU F 1 496 ? 2.823   7.786   45.910 1.00 9.72   ? 698 GLU F N   1 
ATOM   18423 C CA  . GLU F 1 496 ? 3.905   6.842   45.680 1.00 11.60  ? 698 GLU F CA  1 
ATOM   18424 C C   . GLU F 1 496 ? 3.561   5.867   44.563 1.00 10.40  ? 698 GLU F C   1 
ATOM   18425 O O   . GLU F 1 496 ? 2.401   5.692   44.185 1.00 10.02  ? 698 GLU F O   1 
ATOM   18426 C CB  . GLU F 1 496 ? 4.197   6.035   46.941 1.00 6.95   ? 698 GLU F CB  1 
ATOM   18427 C CG  . GLU F 1 496 ? 4.816   6.764   48.104 1.00 15.36  ? 698 GLU F CG  1 
ATOM   18428 C CD  . GLU F 1 496 ? 6.221   7.245   47.838 1.00 21.09  ? 698 GLU F CD  1 
ATOM   18429 O OE1 . GLU F 1 496 ? 6.938   6.581   47.064 1.00 22.76  ? 698 GLU F OE1 1 
ATOM   18430 O OE2 . GLU F 1 496 ? 6.631   8.244   48.457 1.00 22.97  ? 698 GLU F OE2 1 
ATOM   18431 N N   . ILE F 1 497 ? 4.592   5.222   44.039 1.00 11.99  ? 699 ILE F N   1 
ATOM   18432 C CA  . ILE F 1 497 ? 4.409   4.020   43.237 1.00 11.96  ? 699 ILE F CA  1 
ATOM   18433 C C   . ILE F 1 497 ? 4.137   2.850   44.169 1.00 11.37  ? 699 ILE F C   1 
ATOM   18434 O O   . ILE F 1 497 ? 4.791   2.696   45.205 1.00 11.09  ? 699 ILE F O   1 
ATOM   18435 C CB  . ILE F 1 497 ? 5.639   3.759   42.353 1.00 10.67  ? 699 ILE F CB  1 
ATOM   18436 C CG1 . ILE F 1 497 ? 5.767   4.838   41.287 1.00 12.05  ? 699 ILE F CG1 1 
ATOM   18437 C CG2 . ILE F 1 497 ? 5.548   2.404   41.689 1.00 11.12  ? 699 ILE F CG2 1 
ATOM   18438 C CD1 . ILE F 1 497 ? 7.045   4.757   40.520 1.00 16.41  ? 699 ILE F CD1 1 
ATOM   18439 N N   . GLN F 1 498 ? 3.155   2.028   43.812 1.00 11.33  ? 700 GLN F N   1 
ATOM   18440 C CA  . GLN F 1 498 ? 2.768   0.875   44.606 1.00 10.79  ? 700 GLN F CA  1 
ATOM   18441 C C   . GLN F 1 498 ? 2.825   -0.364  43.729 1.00 11.12  ? 700 GLN F C   1 
ATOM   18442 O O   . GLN F 1 498 ? 2.804   -0.281  42.500 1.00 11.84  ? 700 GLN F O   1 
ATOM   18443 C CB  . GLN F 1 498 ? 1.353   1.028   45.177 1.00 8.03   ? 700 GLN F CB  1 
ATOM   18444 C CG  . GLN F 1 498 ? 1.131   2.278   46.002 1.00 9.08   ? 700 GLN F CG  1 
ATOM   18445 C CD  . GLN F 1 498 ? 1.892   2.303   47.304 1.00 9.37   ? 700 GLN F CD  1 
ATOM   18446 O OE1 . GLN F 1 498 ? 2.991   2.843   47.384 1.00 9.35   ? 700 GLN F OE1 1 
ATOM   18447 N NE2 . GLN F 1 498 ? 1.286   1.765   48.347 1.00 8.62   ? 700 GLN F NE2 1 
ATOM   18448 N N   . TYR F 1 499 ? 2.885   -1.523  44.372 1.00 10.18  ? 701 TYR F N   1 
ATOM   18449 C CA  . TYR F 1 499 ? 2.752   -2.773  43.642 1.00 10.28  ? 701 TYR F CA  1 
ATOM   18450 C C   . TYR F 1 499 ? 1.284   -3.175  43.619 1.00 11.53  ? 701 TYR F C   1 
ATOM   18451 O O   . TYR F 1 499 ? 0.703   -3.495  44.660 1.00 11.35  ? 701 TYR F O   1 
ATOM   18452 C CB  . TYR F 1 499 ? 3.601   -3.876  44.265 1.00 10.41  ? 701 TYR F CB  1 
ATOM   18453 C CG  . TYR F 1 499 ? 3.363   -5.187  43.576 1.00 11.34  ? 701 TYR F CG  1 
ATOM   18454 C CD1 . TYR F 1 499 ? 3.885   -5.426  42.320 1.00 12.56  ? 701 TYR F CD1 1 
ATOM   18455 C CD2 . TYR F 1 499 ? 2.586   -6.171  44.161 1.00 11.47  ? 701 TYR F CD2 1 
ATOM   18456 C CE1 . TYR F 1 499 ? 3.655   -6.607  41.672 1.00 13.58  ? 701 TYR F CE1 1 
ATOM   18457 C CE2 . TYR F 1 499 ? 2.349   -7.360  43.517 1.00 13.72  ? 701 TYR F CE2 1 
ATOM   18458 C CZ  . TYR F 1 499 ? 2.887   -7.570  42.272 1.00 14.52  ? 701 TYR F CZ  1 
ATOM   18459 O OH  . TYR F 1 499 ? 2.664   -8.751  41.618 1.00 15.19  ? 701 TYR F OH  1 
ATOM   18460 N N   . THR F 1 500 ? 0.695   -3.141  42.438 1.00 8.99   ? 702 THR F N   1 
ATOM   18461 C CA  . THR F 1 500 ? -0.705  -3.437  42.297 1.00 12.60  ? 702 THR F CA  1 
ATOM   18462 C C   . THR F 1 500 ? -0.962  -4.554  41.322 1.00 15.20  ? 702 THR F C   1 
ATOM   18463 O O   . THR F 1 500 ? -0.182  -4.786  40.413 1.00 15.52  ? 702 THR F O   1 
ATOM   18464 C CB  . THR F 1 500 ? -1.444  -2.193  41.782 1.00 14.07  ? 702 THR F CB  1 
ATOM   18465 O OG1 . THR F 1 500 ? -2.827  -2.495  41.600 1.00 14.50  ? 702 THR F OG1 1 
ATOM   18466 C CG2 . THR F 1 500 ? -0.868  -1.759  40.464 1.00 12.78  ? 702 THR F CG2 1 
ATOM   18467 N N   . SER F 1 501 ? -2.055  -5.263  41.556 1.00 11.01  ? 703 SER F N   1 
ATOM   18468 C CA  . SER F 1 501 ? -2.519  -6.333  40.695 1.00 15.82  ? 703 SER F CA  1 
ATOM   18469 C C   . SER F 1 501 ? -3.135  -5.721  39.439 1.00 19.20  ? 703 SER F C   1 
ATOM   18470 O O   . SER F 1 501 ? -3.586  -4.585  39.460 1.00 19.84  ? 703 SER F O   1 
ATOM   18471 C CB  . SER F 1 501 ? -3.535  -7.178  41.453 1.00 13.77  ? 703 SER F CB  1 
ATOM   18472 O OG  . SER F 1 501 ? -4.622  -7.544  40.633 1.00 15.38  ? 703 SER F OG  1 
ATOM   18473 N N   . ASN F 1 502 ? -3.139  -6.455  38.337 1.00 16.04  ? 704 ASN F N   1 
ATOM   18474 C CA  . ASN F 1 502 ? -3.716  -5.942  37.094 1.00 20.77  ? 704 ASN F CA  1 
ATOM   18475 C C   . ASN F 1 502 ? -5.241  -5.851  37.096 1.00 23.00  ? 704 ASN F C   1 
ATOM   18476 O O   . ASN F 1 502 ? -5.916  -6.772  37.521 1.00 23.90  ? 704 ASN F O   1 
ATOM   18477 C CB  . ASN F 1 502 ? -3.263  -6.808  35.928 1.00 25.03  ? 704 ASN F CB  1 
ATOM   18478 C CG  . ASN F 1 502 ? -1.816  -6.576  35.568 1.00 27.90  ? 704 ASN F CG  1 
ATOM   18479 O OD1 . ASN F 1 502 ? -1.028  -7.515  35.479 1.00 29.65  ? 704 ASN F OD1 1 
ATOM   18480 N ND2 . ASN F 1 502 ? -1.455  -5.317  35.370 1.00 28.31  ? 704 ASN F ND2 1 
ATOM   18481 N N   . TYR F 1 503 ? -5.772  -4.734  36.614 1.00 20.36  ? 705 TYR F N   1 
ATOM   18482 C CA  . TYR F 1 503 ? -7.218  -4.508  36.537 1.00 23.66  ? 705 TYR F CA  1 
ATOM   18483 C C   . TYR F 1 503 ? -8.001  -5.407  35.559 1.00 23.43  ? 705 TYR F C   1 
ATOM   18484 O O   . TYR F 1 503 ? -9.134  -5.777  35.840 1.00 23.28  ? 705 TYR F O   1 
ATOM   18485 C CB  . TYR F 1 503 ? -7.556  -3.005  36.339 1.00 16.50  ? 705 TYR F CB  1 
ATOM   18486 C CG  . TYR F 1 503 ? -7.601  -2.557  34.896 1.00 22.91  ? 705 TYR F CG  1 
ATOM   18487 C CD1 . TYR F 1 503 ? -8.727  -2.791  34.121 1.00 25.51  ? 705 TYR F CD1 1 
ATOM   18488 C CD2 . TYR F 1 503 ? -6.502  -1.979  34.290 1.00 24.58  ? 705 TYR F CD2 1 
ATOM   18489 C CE1 . TYR F 1 503 ? -8.768  -2.433  32.793 1.00 26.96  ? 705 TYR F CE1 1 
ATOM   18490 C CE2 . TYR F 1 503 ? -6.538  -1.615  32.963 1.00 25.85  ? 705 TYR F CE2 1 
ATOM   18491 C CZ  . TYR F 1 503 ? -7.674  -1.845  32.223 1.00 27.07  ? 705 TYR F CZ  1 
ATOM   18492 O OH  . TYR F 1 503 ? -7.714  -1.484  30.904 1.00 25.55  ? 705 TYR F OH  1 
ATOM   18493 N N   . TYR F 1 504 ? -7.394  -5.737  34.419 1.00 24.31  ? 706 TYR F N   1 
ATOM   18494 C CA  . TYR F 1 504 ? -8.033  -6.474  33.330 1.00 23.72  ? 706 TYR F CA  1 
ATOM   18495 C C   . TYR F 1 504 ? -8.331  -7.943  33.509 1.00 19.88  ? 706 TYR F C   1 
ATOM   18496 O O   . TYR F 1 504 ? -7.696  -8.632  34.293 1.00 18.93  ? 706 TYR F O   1 
ATOM   18497 C CB  . TYR F 1 504 ? -7.207  -6.313  32.065 1.00 14.41  ? 706 TYR F CB  1 
ATOM   18498 C CG  . TYR F 1 504 ? -5.799  -6.796  32.241 1.00 22.46  ? 706 TYR F CG  1 
ATOM   18499 C CD1 . TYR F 1 504 ? -5.512  -8.146  32.266 1.00 25.23  ? 706 TYR F CD1 1 
ATOM   18500 C CD2 . TYR F 1 504 ? -4.758  -5.903  32.399 1.00 24.53  ? 706 TYR F CD2 1 
ATOM   18501 C CE1 . TYR F 1 504 ? -4.225  -8.596  32.433 1.00 27.50  ? 706 TYR F CE1 1 
ATOM   18502 C CE2 . TYR F 1 504 ? -3.468  -6.343  32.567 1.00 27.50  ? 706 TYR F CE2 1 
ATOM   18503 C CZ  . TYR F 1 504 ? -3.210  -7.690  32.583 1.00 28.50  ? 706 TYR F CZ  1 
ATOM   18504 O OH  . TYR F 1 504 ? -1.925  -8.132  32.752 1.00 28.89  ? 706 TYR F OH  1 
ATOM   18505 N N   . LYS F 1 505 ? -9.323  -8.403  32.754 1.00 23.56  ? 707 LYS F N   1 
ATOM   18506 C CA  . LYS F 1 505 ? -9.742  -9.792  32.754 1.00 19.79  ? 707 LYS F CA  1 
ATOM   18507 C C   . LYS F 1 505 ? -8.700  -10.688 32.111 1.00 18.24  ? 707 LYS F C   1 
ATOM   18508 O O   . LYS F 1 505 ? -8.127  -10.352 31.088 1.00 17.70  ? 707 LYS F O   1 
ATOM   18509 C CB  . LYS F 1 505 ? -11.048 -9.938  31.992 1.00 19.69  ? 707 LYS F CB  1 
ATOM   18510 C CG  . LYS F 1 505 ? -10.895 -9.690  30.509 1.00 18.64  ? 707 LYS F CG  1 
ATOM   18511 C CD  . LYS F 1 505 ? -12.190 -9.958  29.777 1.00 18.29  ? 707 LYS F CD  1 
ATOM   18512 C CE  . LYS F 1 505 ? -12.078 -9.524  28.332 1.00 18.65  ? 707 LYS F CE  1 
ATOM   18513 N NZ  . LYS F 1 505 ? -13.285 -9.924  27.568 1.00 19.99  ? 707 LYS F NZ  1 
ATOM   18514 N N   . SER F 1 506 ? -8.480  -11.845 32.715 1.00 22.59  ? 708 SER F N   1 
ATOM   18515 C CA  . SER F 1 506 ? -7.520  -12.817 32.230 1.00 21.59  ? 708 SER F CA  1 
ATOM   18516 C C   . SER F 1 506 ? -8.084  -14.197 32.475 1.00 20.10  ? 708 SER F C   1 
ATOM   18517 O O   . SER F 1 506 ? -8.960  -14.369 33.310 1.00 18.84  ? 708 SER F O   1 
ATOM   18518 C CB  . SER F 1 506 ? -6.194  -12.663 32.961 1.00 23.51  ? 708 SER F CB  1 
ATOM   18519 O OG  . SER F 1 506 ? -6.370  -12.793 34.357 1.00 25.94  ? 708 SER F OG  1 
ATOM   18520 N N   . ASN F 1 507 ? -7.592  -15.187 31.748 1.00 20.66  ? 709 ASN F N   1 
ATOM   18521 C CA  . ASN F 1 507 ? -8.078  -16.544 31.923 1.00 20.69  ? 709 ASN F CA  1 
ATOM   18522 C C   . ASN F 1 507 ? -7.819  -17.071 33.322 1.00 19.97  ? 709 ASN F C   1 
ATOM   18523 O O   . ASN F 1 507 ? -8.629  -17.801 33.870 1.00 20.44  ? 709 ASN F O   1 
ATOM   18524 C CB  . ASN F 1 507 ? -7.423  -17.473 30.909 1.00 20.77  ? 709 ASN F CB  1 
ATOM   18525 C CG  . ASN F 1 507 ? -7.989  -17.303 29.523 1.00 22.54  ? 709 ASN F CG  1 
ATOM   18526 O OD1 . ASN F 1 507 ? -9.033  -16.689 29.340 1.00 22.08  ? 709 ASN F OD1 1 
ATOM   18527 N ND2 . ASN F 1 507 ? -7.300  -17.846 28.535 1.00 25.13  ? 709 ASN F ND2 1 
ATOM   18528 N N   . ASN F 1 508 ? -6.694  -16.672 33.899 1.00 22.45  ? 710 ASN F N   1 
ATOM   18529 C CA  . ASN F 1 508 ? -6.272  -17.142 35.207 1.00 21.49  ? 710 ASN F CA  1 
ATOM   18530 C C   . ASN F 1 508 ? -6.050  -15.962 36.136 1.00 20.32  ? 710 ASN F C   1 
ATOM   18531 O O   . ASN F 1 508 ? -5.521  -14.927 35.725 1.00 20.99  ? 710 ASN F O   1 
ATOM   18532 C CB  . ASN F 1 508 ? -4.978  -17.959 35.116 1.00 19.17  ? 710 ASN F CB  1 
ATOM   18533 C CG  . ASN F 1 508 ? -5.166  -19.279 34.405 1.00 21.60  ? 710 ASN F CG  1 
ATOM   18534 O OD1 . ASN F 1 508 ? -5.692  -20.231 34.972 1.00 23.86  ? 710 ASN F OD1 1 
ATOM   18535 N ND2 . ASN F 1 508 ? -4.721  -19.347 33.160 1.00 22.22  ? 710 ASN F ND2 1 
ATOM   18536 N N   . VAL F 1 509 ? -6.456  -16.127 37.392 1.00 22.56  ? 711 VAL F N   1 
ATOM   18537 C CA  . VAL F 1 509 ? -6.061  -15.190 38.432 1.00 19.41  ? 711 VAL F CA  1 
ATOM   18538 C C   . VAL F 1 509 ? -4.579  -15.367 38.725 1.00 20.11  ? 711 VAL F C   1 
ATOM   18539 O O   . VAL F 1 509 ? -4.105  -16.487 38.956 1.00 19.64  ? 711 VAL F O   1 
ATOM   18540 C CB  . VAL F 1 509 ? -6.909  -15.410 39.695 1.00 17.75  ? 711 VAL F CB  1 
ATOM   18541 C CG1 . VAL F 1 509 ? -6.374  -14.590 40.831 1.00 16.59  ? 711 VAL F CG1 1 
ATOM   18542 C CG2 . VAL F 1 509 ? -8.352  -15.047 39.426 1.00 16.70  ? 711 VAL F CG2 1 
ATOM   18543 N N   . GLU F 1 510 ? -3.832  -14.266 38.700 1.00 20.92  ? 712 GLU F N   1 
ATOM   18544 C CA  . GLU F 1 510 ? -2.406  -14.338 38.981 1.00 21.30  ? 712 GLU F CA  1 
ATOM   18545 C C   . GLU F 1 510 ? -2.167  -14.738 40.429 1.00 19.36  ? 712 GLU F C   1 
ATOM   18546 O O   . GLU F 1 510 ? -2.905  -14.341 41.334 1.00 19.93  ? 712 GLU F O   1 
ATOM   18547 C CB  . GLU F 1 510 ? -1.728  -13.003 38.696 1.00 21.48  ? 712 GLU F CB  1 
ATOM   18548 C CG  . GLU F 1 510 ? -1.706  -12.621 37.235 1.00 29.65  ? 712 GLU F CG  1 
ATOM   18549 C CD  . GLU F 1 510 ? -1.036  -11.285 36.998 1.00 34.98  ? 712 GLU F CD  1 
ATOM   18550 O OE1 . GLU F 1 510 ? -0.736  -10.589 37.990 1.00 35.90  ? 712 GLU F OE1 1 
ATOM   18551 O OE2 . GLU F 1 510 ? -0.812  -10.929 35.822 1.00 37.86  ? 712 GLU F OE2 1 
ATOM   18552 N N   . PHE F 1 511 ? -1.118  -15.535 40.639 1.00 19.79  ? 713 PHE F N   1 
ATOM   18553 C CA  . PHE F 1 511 ? -0.801  -16.099 41.951 1.00 17.30  ? 713 PHE F CA  1 
ATOM   18554 C C   . PHE F 1 511 ? -1.943  -16.973 42.459 1.00 15.96  ? 713 PHE F C   1 
ATOM   18555 O O   . PHE F 1 511 ? -2.373  -16.860 43.606 1.00 16.26  ? 713 PHE F O   1 
ATOM   18556 C CB  . PHE F 1 511 ? -0.456  -15.006 42.963 1.00 16.20  ? 713 PHE F CB  1 
ATOM   18557 C CG  . PHE F 1 511 ? 0.758   -14.209 42.598 1.00 15.22  ? 713 PHE F CG  1 
ATOM   18558 C CD1 . PHE F 1 511 ? 2.019   -14.666 42.915 1.00 15.48  ? 713 PHE F CD1 1 
ATOM   18559 C CD2 . PHE F 1 511 ? 0.637   -13.008 41.927 1.00 15.41  ? 713 PHE F CD2 1 
ATOM   18560 C CE1 . PHE F 1 511 ? 3.134   -13.938 42.578 1.00 15.72  ? 713 PHE F CE1 1 
ATOM   18561 C CE2 . PHE F 1 511 ? 1.750   -12.278 41.587 1.00 16.06  ? 713 PHE F CE2 1 
ATOM   18562 C CZ  . PHE F 1 511 ? 2.998   -12.745 41.910 1.00 16.48  ? 713 PHE F CZ  1 
ATOM   18563 N N   . ALA F 1 512 ? -2.438  -17.851 41.589 1.00 16.58  ? 714 ALA F N   1 
ATOM   18564 C CA  . ALA F 1 512 ? -3.497  -18.790 41.922 1.00 15.40  ? 714 ALA F CA  1 
ATOM   18565 C C   . ALA F 1 512 ? -3.306  -20.056 41.097 1.00 15.76  ? 714 ALA F C   1 
ATOM   18566 O O   . ALA F 1 512 ? -2.390  -20.157 40.278 1.00 15.05  ? 714 ALA F O   1 
ATOM   18567 C CB  . ALA F 1 512 ? -4.879  -18.176 41.681 1.00 15.92  ? 714 ALA F CB  1 
ATOM   18568 N N   . VAL F 1 513 ? -4.168  -21.028 41.326 1.00 14.27  ? 715 VAL F N   1 
ATOM   18569 C CA  . VAL F 1 513 ? -4.129  -22.302 40.618 1.00 15.18  ? 715 VAL F CA  1 
ATOM   18570 C C   . VAL F 1 513 ? -4.814  -22.162 39.266 1.00 16.09  ? 715 VAL F C   1 
ATOM   18571 O O   . VAL F 1 513 ? -5.655  -21.284 39.058 1.00 15.88  ? 715 VAL F O   1 
ATOM   18572 C CB  . VAL F 1 513 ? -4.776  -23.416 41.465 1.00 13.74  ? 715 VAL F CB  1 
ATOM   18573 C CG1 . VAL F 1 513 ? -4.018  -23.594 42.763 1.00 14.91  ? 715 VAL F CG1 1 
ATOM   18574 C CG2 . VAL F 1 513 ? -6.227  -23.102 41.731 1.00 14.87  ? 715 VAL F CG2 1 
ATOM   18575 N N   . ASN F 1 514 ? -4.441  -23.027 38.330 1.00 16.83  ? 716 ASN F N   1 
ATOM   18576 C CA  . ASN F 1 514 ? -5.103  -23.103 37.038 1.00 18.43  ? 716 ASN F CA  1 
ATOM   18577 C C   . ASN F 1 514 ? -6.145  -24.221 37.069 1.00 18.94  ? 716 ASN F C   1 
ATOM   18578 O O   . ASN F 1 514 ? -6.440  -24.793 38.121 1.00 20.12  ? 716 ASN F O   1 
ATOM   18579 C CB  . ASN F 1 514 ? -4.077  -23.297 35.925 1.00 17.41  ? 716 ASN F CB  1 
ATOM   18580 C CG  . ASN F 1 514 ? -3.320  -24.600 36.047 1.00 20.10  ? 716 ASN F CG  1 
ATOM   18581 O OD1 . ASN F 1 514 ? -3.356  -25.261 37.081 1.00 25.81  ? 716 ASN F OD1 1 
ATOM   18582 N ND2 . ASN F 1 514 ? -2.622  -24.974 34.986 1.00 21.84  ? 716 ASN F ND2 1 
ATOM   18583 N N   . THR F 1 515 ? -6.720  -24.546 35.910 1.00 22.17  ? 717 THR F N   1 
ATOM   18584 C CA  . THR F 1 515 ? -7.754  -25.575 35.867 1.00 21.96  ? 717 THR F CA  1 
ATOM   18585 C C   . THR F 1 515 ? -7.198  -26.943 36.243 1.00 23.38  ? 717 THR F C   1 
ATOM   18586 O O   . THR F 1 515 ? -7.889  -27.748 36.877 1.00 22.50  ? 717 THR F O   1 
ATOM   18587 C CB  . THR F 1 515 ? -8.391  -25.627 34.481 1.00 24.34  ? 717 THR F CB  1 
ATOM   18588 O OG1 . THR F 1 515 ? -7.383  -25.913 33.506 1.00 23.03  ? 717 THR F OG1 1 
ATOM   18589 C CG2 . THR F 1 515 ? -9.048  -24.302 34.150 1.00 23.75  ? 717 THR F CG2 1 
ATOM   18590 N N   . GLU F 1 516 ? -5.951  -27.226 35.862 1.00 23.43  ? 718 GLU F N   1 
ATOM   18591 C CA  . GLU F 1 516 ? -5.364  -28.527 36.165 1.00 25.37  ? 718 GLU F CA  1 
ATOM   18592 C C   . GLU F 1 516 ? -4.853  -28.587 37.598 1.00 23.68  ? 718 GLU F C   1 
ATOM   18593 O O   . GLU F 1 516 ? -4.463  -29.655 38.080 1.00 23.76  ? 718 GLU F O   1 
ATOM   18594 C CB  . GLU F 1 516 ? -4.240  -28.842 35.183 1.00 19.71  ? 718 GLU F CB  1 
ATOM   18595 C CG  . GLU F 1 516 ? -4.705  -29.090 33.761 1.00 30.55  ? 718 GLU F CG  1 
ATOM   18596 C CD  . GLU F 1 516 ? -4.917  -27.817 32.971 1.00 36.13  ? 718 GLU F CD  1 
ATOM   18597 O OE1 . GLU F 1 516 ? -4.765  -26.720 33.543 1.00 39.64  ? 718 GLU F OE1 1 
ATOM   18598 O OE2 . GLU F 1 516 ? -5.236  -27.914 31.769 1.00 38.93  ? 718 GLU F OE2 1 
ATOM   18599 N N   . GLY F 1 517 ? -4.846  -27.454 38.291 1.00 22.44  ? 719 GLY F N   1 
ATOM   18600 C CA  . GLY F 1 517 ? -4.482  -27.411 39.696 1.00 19.33  ? 719 GLY F CA  1 
ATOM   18601 C C   . GLY F 1 517 ? -3.082  -26.919 39.989 1.00 17.02  ? 719 GLY F C   1 
ATOM   18602 O O   . GLY F 1 517 ? -2.658  -26.982 41.150 1.00 17.33  ? 719 GLY F O   1 
ATOM   18603 N N   . VAL F 1 518 ? -2.337  -26.417 39.007 1.00 18.34  ? 720 VAL F N   1 
ATOM   18604 C CA  . VAL F 1 518 ? -0.955  -26.027 39.245 1.00 16.08  ? 720 VAL F CA  1 
ATOM   18605 C C   . VAL F 1 518 ? -0.892  -24.575 39.696 1.00 16.55  ? 720 VAL F C   1 
ATOM   18606 O O   . VAL F 1 518 ? -1.443  -23.677 39.047 1.00 16.90  ? 720 VAL F O   1 
ATOM   18607 C CB  . VAL F 1 518 ? -0.116  -26.255 37.979 1.00 18.94  ? 720 VAL F CB  1 
ATOM   18608 C CG1 . VAL F 1 518 ? 1.290   -25.757 38.188 1.00 15.52  ? 720 VAL F CG1 1 
ATOM   18609 C CG2 . VAL F 1 518 ? -0.109  -27.722 37.620 1.00 16.41  ? 720 VAL F CG2 1 
ATOM   18610 N N   . TYR F 1 519 ? -0.218  -24.339 40.815 1.00 14.17  ? 721 TYR F N   1 
ATOM   18611 C CA  . TYR F 1 519 ? 0.006   -22.997 41.330 1.00 15.32  ? 721 TYR F CA  1 
ATOM   18612 C C   . TYR F 1 519 ? 1.218   -22.384 40.648 1.00 16.15  ? 721 TYR F C   1 
ATOM   18613 O O   . TYR F 1 519 ? 2.249   -23.040 40.493 1.00 15.79  ? 721 TYR F O   1 
ATOM   18614 C CB  . TYR F 1 519 ? 0.222   -23.024 42.842 1.00 15.67  ? 721 TYR F CB  1 
ATOM   18615 C CG  . TYR F 1 519 ? 0.574   -21.683 43.434 1.00 16.12  ? 721 TYR F CG  1 
ATOM   18616 C CD1 . TYR F 1 519 ? -0.405  -20.735 43.688 1.00 15.51  ? 721 TYR F CD1 1 
ATOM   18617 C CD2 . TYR F 1 519 ? 1.886   -21.362 43.737 1.00 15.58  ? 721 TYR F CD2 1 
ATOM   18618 C CE1 . TYR F 1 519 ? -0.085  -19.510 44.233 1.00 16.14  ? 721 TYR F CE1 1 
ATOM   18619 C CE2 . TYR F 1 519 ? 2.212   -20.142 44.278 1.00 17.07  ? 721 TYR F CE2 1 
ATOM   18620 C CZ  . TYR F 1 519 ? 1.225   -19.221 44.523 1.00 17.19  ? 721 TYR F CZ  1 
ATOM   18621 O OH  . TYR F 1 519 ? 1.555   -18.003 45.063 1.00 17.65  ? 721 TYR F OH  1 
ATOM   18622 N N   . SER F 1 520 ? 1.127   -21.119 40.279 1.00 14.05  ? 722 SER F N   1 
ATOM   18623 C CA  . SER F 1 520 ? 2.252   -20.481 39.625 1.00 16.16  ? 722 SER F CA  1 
ATOM   18624 C C   . SER F 1 520 ? 2.380   -19.025 39.998 1.00 17.54  ? 722 SER F C   1 
ATOM   18625 O O   . SER F 1 520 ? 1.399   -18.373 40.327 1.00 18.49  ? 722 SER F O   1 
ATOM   18626 C CB  . SER F 1 520 ? 2.100   -20.576 38.112 1.00 16.27  ? 722 SER F CB  1 
ATOM   18627 O OG  . SER F 1 520 ? 1.180   -19.610 37.646 1.00 19.75  ? 722 SER F OG  1 
ATOM   18628 N N   . GLU F 1 521 ? 3.608   -18.526 39.960 1.00 17.94  ? 723 GLU F N   1 
ATOM   18629 C CA  . GLU F 1 521 ? 3.869   -17.128 40.224 1.00 18.94  ? 723 GLU F CA  1 
ATOM   18630 C C   . GLU F 1 521 ? 4.309   -16.577 38.882 1.00 18.41  ? 723 GLU F C   1 
ATOM   18631 O O   . GLU F 1 521 ? 5.302   -17.026 38.326 1.00 19.10  ? 723 GLU F O   1 
ATOM   18632 C CB  . GLU F 1 521 ? 4.973   -16.992 41.258 1.00 16.69  ? 723 GLU F CB  1 
ATOM   18633 C CG  . GLU F 1 521 ? 4.641   -17.684 42.566 1.00 20.47  ? 723 GLU F CG  1 
ATOM   18634 C CD  . GLU F 1 521 ? 5.858   -17.956 43.426 1.00 22.91  ? 723 GLU F CD  1 
ATOM   18635 O OE1 . GLU F 1 521 ? 6.722   -18.754 43.010 1.00 23.69  ? 723 GLU F OE1 1 
ATOM   18636 O OE2 . GLU F 1 521 ? 5.943   -17.385 44.529 1.00 23.56  ? 723 GLU F OE2 1 
ATOM   18637 N N   . PRO F 1 522 ? 3.544   -15.626 38.339 1.00 20.51  ? 724 PRO F N   1 
ATOM   18638 C CA  . PRO F 1 522 ? 3.770   -14.976 37.044 1.00 20.67  ? 724 PRO F CA  1 
ATOM   18639 C C   . PRO F 1 522 ? 5.022   -14.113 36.909 1.00 20.89  ? 724 PRO F C   1 
ATOM   18640 O O   . PRO F 1 522 ? 5.659   -14.139 35.863 1.00 21.23  ? 724 PRO F O   1 
ATOM   18641 C CB  . PRO F 1 522 ? 2.520   -14.115 36.865 1.00 19.16  ? 724 PRO F CB  1 
ATOM   18642 C CG  . PRO F 1 522 ? 2.026   -13.878 38.244 1.00 20.25  ? 724 PRO F CG  1 
ATOM   18643 C CD  . PRO F 1 522 ? 2.316   -15.143 38.984 1.00 19.12  ? 724 PRO F CD  1 
ATOM   18644 N N   . ARG F 1 523 ? 5.357   -13.352 37.941 1.00 20.70  ? 725 ARG F N   1 
ATOM   18645 C CA  . ARG F 1 523 ? 6.495   -12.451 37.879 1.00 20.78  ? 725 ARG F CA  1 
ATOM   18646 C C   . ARG F 1 523 ? 7.285   -12.416 39.165 1.00 19.91  ? 725 ARG F C   1 
ATOM   18647 O O   . ARG F 1 523 ? 6.795   -12.829 40.204 1.00 19.84  ? 725 ARG F O   1 
ATOM   18648 C CB  . ARG F 1 523 ? 5.994   -11.046 37.606 1.00 19.16  ? 725 ARG F CB  1 
ATOM   18649 C CG  . ARG F 1 523 ? 5.147   -10.501 38.739 1.00 23.75  ? 725 ARG F CG  1 
ATOM   18650 C CD  . ARG F 1 523 ? 4.435   -9.234  38.325 1.00 31.21  ? 725 ARG F CD  1 
ATOM   18651 N NE  . ARG F 1 523 ? 3.612   -9.459  37.146 1.00 39.93  ? 725 ARG F NE  1 
ATOM   18652 C CZ  . ARG F 1 523 ? 2.864   -8.525  36.576 1.00 43.52  ? 725 ARG F CZ  1 
ATOM   18653 N NH1 . ARG F 1 523 ? 2.836   -7.301  37.084 1.00 44.15  ? 725 ARG F NH1 1 
ATOM   18654 N NH2 . ARG F 1 523 ? 2.144   -8.816  35.502 1.00 43.70  ? 725 ARG F NH2 1 
ATOM   18655 N N   . PRO F 1 524 ? 8.533   -11.946 39.091 1.00 19.40  ? 726 PRO F N   1 
ATOM   18656 C CA  . PRO F 1 524 ? 9.376   -11.808 40.273 1.00 18.39  ? 726 PRO F CA  1 
ATOM   18657 C C   . PRO F 1 524 ? 9.027   -10.469 40.878 1.00 16.98  ? 726 PRO F C   1 
ATOM   18658 O O   . PRO F 1 524 ? 9.013   -9.492  40.148 1.00 17.24  ? 726 PRO F O   1 
ATOM   18659 C CB  . PRO F 1 524 ? 10.771  -11.754 39.677 1.00 19.32  ? 726 PRO F CB  1 
ATOM   18660 C CG  . PRO F 1 524 ? 10.571  -11.070 38.374 1.00 20.42  ? 726 PRO F CG  1 
ATOM   18661 C CD  . PRO F 1 524 ? 9.209   -11.465 37.878 1.00 20.17  ? 726 PRO F CD  1 
ATOM   18662 N N   . ILE F 1 525 ? 8.758   -10.410 42.173 1.00 16.44  ? 727 ILE F N   1 
ATOM   18663 C CA  . ILE F 1 525 ? 8.376   -9.154  42.802 1.00 13.81  ? 727 ILE F CA  1 
ATOM   18664 C C   . ILE F 1 525 ? 9.434   -8.564  43.728 1.00 13.18  ? 727 ILE F C   1 
ATOM   18665 O O   . ILE F 1 525 ? 9.730   -9.139  44.759 1.00 12.75  ? 727 ILE F O   1 
ATOM   18666 C CB  . ILE F 1 525 ? 7.084   -9.336  43.620 1.00 13.22  ? 727 ILE F CB  1 
ATOM   18667 C CG1 . ILE F 1 525 ? 5.980   -9.928  42.754 1.00 12.65  ? 727 ILE F CG1 1 
ATOM   18668 C CG2 . ILE F 1 525 ? 6.628   -8.021  44.217 1.00 11.44  ? 727 ILE F CG2 1 
ATOM   18669 C CD1 . ILE F 1 525 ? 4.706   -10.197 43.515 1.00 13.82  ? 727 ILE F CD1 1 
ATOM   18670 N N   . GLY F 1 526 ? 9.995   -7.409  43.372 1.00 13.98  ? 728 GLY F N   1 
ATOM   18671 C CA  . GLY F 1 526 ? 10.961  -6.759  44.227 1.00 13.97  ? 728 GLY F CA  1 
ATOM   18672 C C   . GLY F 1 526 ? 10.297  -6.031  45.373 1.00 14.34  ? 728 GLY F C   1 
ATOM   18673 O O   . GLY F 1 526 ? 9.083   -5.849  45.407 1.00 14.24  ? 728 GLY F O   1 
ATOM   18674 N N   . THR F 1 527 ? 11.104  -5.618  46.342 1.00 11.43  ? 729 THR F N   1 
ATOM   18675 C CA  . THR F 1 527 ? 10.564  -4.975  47.530 1.00 13.33  ? 729 THR F CA  1 
ATOM   18676 C C   . THR F 1 527 ? 10.633  -3.453  47.479 1.00 13.78  ? 729 THR F C   1 
ATOM   18677 O O   . THR F 1 527 ? 10.197  -2.801  48.432 1.00 16.29  ? 729 THR F O   1 
ATOM   18678 C CB  . THR F 1 527 ? 11.289  -5.479  48.781 1.00 13.68  ? 729 THR F CB  1 
ATOM   18679 O OG1 . THR F 1 527 ? 10.536  -5.128  49.944 1.00 16.44  ? 729 THR F OG1 1 
ATOM   18680 C CG2 . THR F 1 527 ? 12.631  -4.827  48.894 1.00 13.54  ? 729 THR F CG2 1 
ATOM   18681 N N   . ARG F 1 528 ? 11.141  -2.864  46.401 1.00 14.65  ? 730 ARG F N   1 
ATOM   18682 C CA  . ARG F 1 528 ? 11.448  -1.437  46.366 1.00 14.05  ? 730 ARG F CA  1 
ATOM   18683 C C   . ARG F 1 528 ? 10.414  -0.699  45.526 1.00 14.66  ? 730 ARG F C   1 
ATOM   18684 O O   . ARG F 1 528 ? 10.425  -0.782  44.294 1.00 15.15  ? 730 ARG F O   1 
ATOM   18685 C CB  . ARG F 1 528 ? 12.863  -1.232  45.837 1.00 19.73  ? 730 ARG F CB  1 
ATOM   18686 C CG  . ARG F 1 528 ? 13.888  -1.757  46.810 1.00 18.18  ? 730 ARG F CG  1 
ATOM   18687 C CD  . ARG F 1 528 ? 15.308  -1.691  46.313 1.00 17.31  ? 730 ARG F CD  1 
ATOM   18688 N NE  . ARG F 1 528 ? 16.201  -2.199  47.347 1.00 16.96  ? 730 ARG F NE  1 
ATOM   18689 C CZ  . ARG F 1 528 ? 17.486  -2.469  47.169 1.00 17.44  ? 730 ARG F CZ  1 
ATOM   18690 N NH1 . ARG F 1 528 ? 18.040  -2.301  45.982 1.00 18.81  ? 730 ARG F NH1 1 
ATOM   18691 N NH2 . ARG F 1 528 ? 18.212  -2.924  48.177 1.00 16.00  ? 730 ARG F NH2 1 
ATOM   18692 N N   . TYR F 1 529 ? 9.534   0.035   46.205 1.00 14.86  ? 731 TYR F N   1 
ATOM   18693 C CA  . TYR F 1 529 ? 8.479   0.832   45.592 1.00 14.75  ? 731 TYR F CA  1 
ATOM   18694 C C   . TYR F 1 529 ? 8.453   2.237   46.183 1.00 14.38  ? 731 TYR F C   1 
ATOM   18695 O O   . TYR F 1 529 ? 8.554   3.226   45.451 1.00 13.92  ? 731 TYR F O   1 
ATOM   18696 C CB  . TYR F 1 529 ? 7.136   0.117   45.719 1.00 9.60   ? 731 TYR F CB  1 
ATOM   18697 C CG  . TYR F 1 529 ? 7.083   -1.091  44.822 1.00 10.93  ? 731 TYR F CG  1 
ATOM   18698 C CD1 . TYR F 1 529 ? 6.652   -0.981  43.509 1.00 11.70  ? 731 TYR F CD1 1 
ATOM   18699 C CD2 . TYR F 1 529 ? 7.507   -2.331  45.266 1.00 10.93  ? 731 TYR F CD2 1 
ATOM   18700 C CE1 . TYR F 1 529 ? 6.622   -2.072  42.677 1.00 12.77  ? 731 TYR F CE1 1 
ATOM   18701 C CE2 . TYR F 1 529 ? 7.481   -3.427  44.440 1.00 12.36  ? 731 TYR F CE2 1 
ATOM   18702 C CZ  . TYR F 1 529 ? 7.040   -3.293  43.147 1.00 13.27  ? 731 TYR F CZ  1 
ATOM   18703 O OH  . TYR F 1 529 ? 7.013   -4.390  42.322 1.00 14.33  ? 731 TYR F OH  1 
ATOM   18704 N N   . LEU F 1 530 ? 8.284   2.331   47.499 1.00 13.64  ? 732 LEU F N   1 
ATOM   18705 C CA  . LEU F 1 530 ? 8.329   3.606   48.198 1.00 13.46  ? 732 LEU F CA  1 
ATOM   18706 C C   . LEU F 1 530 ? 9.695   4.264   48.011 1.00 14.53  ? 732 LEU F C   1 
ATOM   18707 O O   . LEU F 1 530 ? 10.668  3.626   47.615 1.00 14.82  ? 732 LEU F O   1 
ATOM   18708 C CB  . LEU F 1 530 ? 8.055   3.409   49.686 1.00 12.74  ? 732 LEU F CB  1 
ATOM   18709 C CG  . LEU F 1 530 ? 6.711   2.814   50.102 1.00 13.27  ? 732 LEU F CG  1 
ATOM   18710 C CD1 . LEU F 1 530 ? 6.695   2.589   51.595 1.00 13.86  ? 732 LEU F CD1 1 
ATOM   18711 C CD2 . LEU F 1 530 ? 5.569   3.708   49.695 1.00 11.29  ? 732 LEU F CD2 1 
ATOM   18712 N N   . THR F 1 531 ? 9.747   5.571   48.247 1.00 15.09  ? 733 THR F N   1 
ATOM   18713 C CA  . THR F 1 531 ? 10.932  6.361   47.953 1.00 15.61  ? 733 THR F CA  1 
ATOM   18714 C C   . THR F 1 531 ? 11.442  7.086   49.191 1.00 15.91  ? 733 THR F C   1 
ATOM   18715 O O   . THR F 1 531 ? 10.699  7.354   50.137 1.00 15.75  ? 733 THR F O   1 
ATOM   18716 C CB  . THR F 1 531 ? 10.649  7.385   46.853 1.00 14.99  ? 733 THR F CB  1 
ATOM   18717 O OG1 . THR F 1 531 ? 9.602   8.260   47.279 1.00 17.40  ? 733 THR F OG1 1 
ATOM   18718 C CG2 . THR F 1 531 ? 10.214  6.689   45.592 1.00 14.93  ? 733 THR F CG2 1 
ATOM   18719 N N   . ARG F 1 532 ? 12.735  7.400   49.166 1.00 12.51  ? 734 ARG F N   1 
ATOM   18720 C CA  . ARG F 1 532 ? 13.382  8.219   50.179 1.00 14.04  ? 734 ARG F CA  1 
ATOM   18721 C C   . ARG F 1 532 ? 14.286  9.250   49.523 1.00 15.66  ? 734 ARG F C   1 
ATOM   18722 O O   . ARG F 1 532 ? 14.603  9.172   48.335 1.00 15.85  ? 734 ARG F O   1 
ATOM   18723 C CB  . ARG F 1 532 ? 14.234  7.402   51.154 1.00 13.20  ? 734 ARG F CB  1 
ATOM   18724 C CG  . ARG F 1 532 ? 13.504  6.621   52.215 1.00 15.92  ? 734 ARG F CG  1 
ATOM   18725 C CD  . ARG F 1 532 ? 14.535  5.864   53.023 1.00 18.25  ? 734 ARG F CD  1 
ATOM   18726 N NE  . ARG F 1 532 ? 15.480  6.778   53.650 1.00 23.30  ? 734 ARG F NE  1 
ATOM   18727 C CZ  . ARG F 1 532 ? 15.340  7.285   54.869 1.00 26.44  ? 734 ARG F CZ  1 
ATOM   18728 N NH1 . ARG F 1 532 ? 14.311  6.934   55.620 1.00 26.83  ? 734 ARG F NH1 1 
ATOM   18729 N NH2 . ARG F 1 532 ? 16.248  8.120   55.348 1.00 27.71  ? 734 ARG F NH2 1 
ATOM   18730 N N   . ASN F 1 533 ? 14.708  10.214  50.331 1.00 14.17  ? 735 ASN F N   1 
ATOM   18731 C CA  . ASN F 1 533 ? 15.692  11.190  49.902 1.00 16.94  ? 735 ASN F CA  1 
ATOM   18732 C C   . ASN F 1 533 ? 17.088  10.596  49.981 1.00 19.09  ? 735 ASN F C   1 
ATOM   18733 O O   . ASN F 1 533 ? 17.386  9.765   50.841 1.00 19.47  ? 735 ASN F O   1 
ATOM   18734 C CB  . ASN F 1 533 ? 15.613  12.436  50.775 1.00 20.51  ? 735 ASN F CB  1 
ATOM   18735 C CG  . ASN F 1 533 ? 14.329  13.196  50.575 1.00 22.43  ? 735 ASN F CG  1 
ATOM   18736 O OD1 . ASN F 1 533 ? 13.708  13.112  49.519 1.00 23.01  ? 735 ASN F OD1 1 
ATOM   18737 N ND2 . ASN F 1 533 ? 13.910  13.928  51.597 1.00 23.13  ? 735 ASN F ND2 1 
ATOM   18738 N N   . LEU F 1 534 ? 17.953  11.035  49.078 1.00 13.61  ? 736 LEU F N   1 
ATOM   18739 C CA  . LEU F 1 534 ? 19.320  10.544  49.066 1.00 17.57  ? 736 LEU F CA  1 
ATOM   18740 C C   . LEU F 1 534 ? 20.187  11.376  50.004 1.00 22.10  ? 736 LEU F C   1 
ATOM   18741 O O   . LEU F 1 534 ? 20.140  11.205  51.223 1.00 24.45  ? 736 LEU F O   1 
ATOM   18742 C CB  . LEU F 1 534 ? 19.890  10.571  47.650 1.00 18.60  ? 736 LEU F CB  1 
ATOM   18743 C CG  . LEU F 1 534 ? 21.219  9.852   47.434 1.00 15.00  ? 736 LEU F CG  1 
ATOM   18744 C CD1 . LEU F 1 534 ? 21.346  8.666   48.369 1.00 13.70  ? 736 LEU F CD1 1 
ATOM   18745 C CD2 . LEU F 1 534 ? 21.312  9.393   46.007 1.00 13.42  ? 736 LEU F CD2 1 
ATOM   18746 N N   . SER G 2 1   ? 14.980  4.344   23.950 1.00 41.27  ? 19  SER H N   1 
ATOM   18747 C CA  . SER G 2 1   ? 13.699  3.875   23.436 1.00 41.27  ? 19  SER H CA  1 
ATOM   18748 C C   . SER G 2 1   ? 13.129  2.780   24.327 1.00 41.27  ? 19  SER H C   1 
ATOM   18749 O O   . SER G 2 1   ? 13.289  1.593   24.044 1.00 41.27  ? 19  SER H O   1 
ATOM   18750 C CB  . SER G 2 1   ? 13.850  3.363   22.003 1.00 49.33  ? 19  SER H CB  1 
ATOM   18751 O OG  . SER G 2 1   ? 14.700  2.230   21.957 1.00 49.33  ? 19  SER H OG  1 
ATOM   18752 N N   . GLU G 2 2   ? 12.463  3.186   25.409 1.00 33.95  ? 20  GLU H N   1 
ATOM   18753 C CA  . GLU G 2 2   ? 11.907  2.209   26.339 1.00 33.95  ? 20  GLU H CA  1 
ATOM   18754 C C   . GLU G 2 2   ? 10.753  1.441   25.711 1.00 33.95  ? 20  GLU H C   1 
ATOM   18755 O O   . GLU G 2 2   ? 10.718  0.206   25.766 1.00 33.95  ? 20  GLU H O   1 
ATOM   18756 C CB  . GLU G 2 2   ? 11.454  2.905   27.621 1.00 36.22  ? 20  GLU H CB  1 
ATOM   18757 C CG  . GLU G 2 2   ? 10.897  1.964   28.674 1.00 36.22  ? 20  GLU H CG  1 
ATOM   18758 C CD  . GLU G 2 2   ? 10.522  2.682   29.954 1.00 36.22  ? 20  GLU H CD  1 
ATOM   18759 O OE1 . GLU G 2 2   ? 10.676  3.919   30.009 1.00 36.22  ? 20  GLU H OE1 1 
ATOM   18760 O OE2 . GLU G 2 2   ? 10.072  2.010   30.907 1.00 36.22  ? 20  GLU H OE2 1 
ATOM   18761 N N   . VAL G 2 3   ? 9.803   2.149   25.110 1.00 30.03  ? 21  VAL H N   1 
ATOM   18762 C CA  . VAL G 2 3   ? 8.637   1.510   24.511 1.00 30.03  ? 21  VAL H CA  1 
ATOM   18763 C C   . VAL G 2 3   ? 9.067   0.774   23.251 1.00 30.03  ? 21  VAL H C   1 
ATOM   18764 O O   . VAL G 2 3   ? 9.846   1.296   22.445 1.00 30.03  ? 21  VAL H O   1 
ATOM   18765 C CB  . VAL G 2 3   ? 7.545   2.545   24.209 1.00 23.33  ? 21  VAL H CB  1 
ATOM   18766 C CG1 . VAL G 2 3   ? 6.372   1.884   23.521 1.00 23.33  ? 21  VAL H CG1 1 
ATOM   18767 C CG2 . VAL G 2 3   ? 7.100   3.219   25.488 1.00 23.33  ? 21  VAL H CG2 1 
ATOM   18768 N N   . GLN G 2 4   ? 8.581   -0.449  23.084 1.00 29.37  ? 22  GLN H N   1 
ATOM   18769 C CA  . GLN G 2 4   ? 8.927   -1.257  21.927 1.00 29.37  ? 22  GLN H CA  1 
ATOM   18770 C C   . GLN G 2 4   ? 7.732   -2.049  21.414 1.00 29.37  ? 22  GLN H C   1 
ATOM   18771 O O   . GLN G 2 4   ? 7.070   -2.732  22.182 1.00 29.37  ? 22  GLN H O   1 
ATOM   18772 C CB  . GLN G 2 4   ? 10.053  -2.215  22.300 1.00 35.99  ? 22  GLN H CB  1 
ATOM   18773 C CG  . GLN G 2 4   ? 10.301  -3.320  21.292 1.00 35.99  ? 22  GLN H CG  1 
ATOM   18774 C CD  . GLN G 2 4   ? 11.492  -4.177  21.663 1.00 35.99  ? 22  GLN H CD  1 
ATOM   18775 O OE1 . GLN G 2 4   ? 11.966  -4.144  22.797 1.00 35.99  ? 22  GLN H OE1 1 
ATOM   18776 N NE2 . GLN G 2 4   ? 11.985  -4.948  20.704 1.00 35.99  ? 22  GLN H NE2 1 
ATOM   18777 N N   . LEU G 2 5   ? 7.457   -1.948  20.118 1.00 25.43  ? 23  LEU H N   1 
ATOM   18778 C CA  . LEU G 2 5   ? 6.347   -2.670  19.501 1.00 25.43  ? 23  LEU H CA  1 
ATOM   18779 C C   . LEU G 2 5   ? 6.828   -3.538  18.351 1.00 25.43  ? 23  LEU H C   1 
ATOM   18780 O O   . LEU G 2 5   ? 7.540   -3.064  17.477 1.00 25.43  ? 23  LEU H O   1 
ATOM   18781 C CB  . LEU G 2 5   ? 5.303   -1.691  18.976 1.00 19.66  ? 23  LEU H CB  1 
ATOM   18782 C CG  . LEU G 2 5   ? 4.614   -0.790  19.990 1.00 19.66  ? 23  LEU H CG  1 
ATOM   18783 C CD1 . LEU G 2 5   ? 3.878   0.325   19.280 1.00 19.66  ? 23  LEU H CD1 1 
ATOM   18784 C CD2 . LEU G 2 5   ? 3.659   -1.599  20.846 1.00 19.66  ? 23  LEU H CD2 1 
ATOM   18785 N N   . LEU G 2 6   ? 6.414   -4.798  18.331 1.00 24.42  ? 24  LEU H N   1 
ATOM   18786 C CA  . LEU G 2 6   ? 6.814   -5.712  17.268 1.00 24.42  ? 24  LEU H CA  1 
ATOM   18787 C C   . LEU G 2 6   ? 5.631   -6.312  16.523 1.00 24.42  ? 24  LEU H C   1 
ATOM   18788 O O   . LEU G 2 6   ? 4.592   -6.578  17.111 1.00 24.42  ? 24  LEU H O   1 
ATOM   18789 C CB  . LEU G 2 6   ? 7.660   -6.846  17.822 1.00 31.13  ? 24  LEU H CB  1 
ATOM   18790 C CG  . LEU G 2 6   ? 9.115   -6.567  18.167 1.00 31.13  ? 24  LEU H CG  1 
ATOM   18791 C CD1 . LEU G 2 6   ? 9.272   -6.400  19.667 1.00 31.13  ? 24  LEU H CD1 1 
ATOM   18792 C CD2 . LEU G 2 6   ? 9.972   -7.709  17.649 1.00 31.13  ? 24  LEU H CD2 1 
ATOM   18793 N N   . GLU G 2 7   ? 5.792   -6.512  15.221 1.00 24.48  ? 25  GLU H N   1 
ATOM   18794 C CA  . GLU G 2 7   ? 4.741   -7.098  14.404 1.00 24.48  ? 25  GLU H CA  1 
ATOM   18795 C C   . GLU G 2 7   ? 5.198   -8.397  13.771 1.00 24.48  ? 25  GLU H C   1 
ATOM   18796 O O   . GLU G 2 7   ? 6.326   -8.514  13.315 1.00 24.48  ? 25  GLU H O   1 
ATOM   18797 C CB  . GLU G 2 7   ? 4.285   -6.146  13.305 1.00 23.32  ? 25  GLU H CB  1 
ATOM   18798 C CG  . GLU G 2 7   ? 3.696   -4.844  13.799 1.00 23.32  ? 25  GLU H CG  1 
ATOM   18799 C CD  . GLU G 2 7   ? 4.733   -3.757  13.902 1.00 23.32  ? 25  GLU H CD  1 
ATOM   18800 O OE1 . GLU G 2 7   ? 5.901   -4.078  14.165 1.00 23.32  ? 25  GLU H OE1 1 
ATOM   18801 O OE2 . GLU G 2 7   ? 4.381   -2.585  13.713 1.00 23.32  ? 25  GLU H OE2 1 
ATOM   18802 N N   . SER G 2 8   ? 4.307   -9.376  13.768 1.00 25.42  ? 26  SER H N   1 
ATOM   18803 C CA  . SER G 2 8   ? 4.570   -10.683 13.192 1.00 25.42  ? 26  SER H CA  1 
ATOM   18804 C C   . SER G 2 8   ? 3.321   -11.149 12.464 1.00 25.42  ? 26  SER H C   1 
ATOM   18805 O O   . SER G 2 8   ? 2.247   -10.621 12.689 1.00 25.42  ? 26  SER H O   1 
ATOM   18806 C CB  . SER G 2 8   ? 4.960   -11.683 14.277 1.00 24.01  ? 26  SER H CB  1 
ATOM   18807 O OG  . SER G 2 8   ? 3.887   -11.926 15.164 1.00 24.01  ? 26  SER H OG  1 
ATOM   18808 N N   . GLY G 2 9   ? 3.442   -12.127 11.585 1.00 29.85  ? 27  GLY H N   1 
ATOM   18809 C CA  . GLY G 2 9   ? 2.266   -12.612 10.892 1.00 29.85  ? 27  GLY H CA  1 
ATOM   18810 C C   . GLY G 2 9   ? 2.038   -11.979 9.542  1.00 29.85  ? 27  GLY H C   1 
ATOM   18811 O O   . GLY G 2 9   ? 0.986   -12.141 8.941  1.00 29.85  ? 27  GLY H O   1 
ATOM   18812 N N   . GLY G 2 10  ? 3.015   -11.212 9.083  1.00 32.84  ? 28  GLY H N   1 
ATOM   18813 C CA  . GLY G 2 10  ? 2.943   -10.591 7.776  1.00 32.84  ? 28  GLY H CA  1 
ATOM   18814 C C   . GLY G 2 10  ? 3.302   -11.619 6.727  1.00 32.84  ? 28  GLY H C   1 
ATOM   18815 O O   . GLY G 2 10  ? 3.954   -12.610 7.039  1.00 32.84  ? 28  GLY H O   1 
ATOM   18816 N N   . GLY G 2 11  ? 2.887   -11.406 5.487  1.00 37.38  ? 29  GLY H N   1 
ATOM   18817 C CA  . GLY G 2 11  ? 3.221   -12.364 4.451  1.00 37.38  ? 29  GLY H CA  1 
ATOM   18818 C C   . GLY G 2 11  ? 2.530   -12.144 3.129  1.00 37.38  ? 29  GLY H C   1 
ATOM   18819 O O   . GLY G 2 11  ? 1.932   -11.101 2.891  1.00 37.38  ? 29  GLY H O   1 
ATOM   18820 N N   . LEU G 2 12  ? 2.635   -13.134 2.255  1.00 38.73  ? 30  LEU H N   1 
ATOM   18821 C CA  . LEU G 2 12  ? 1.986   -13.072 0.961  1.00 38.73  ? 30  LEU H CA  1 
ATOM   18822 C C   . LEU G 2 12  ? 0.739   -13.929 1.060  1.00 38.73  ? 30  LEU H C   1 
ATOM   18823 O O   . LEU G 2 12  ? 0.812   -15.099 1.413  1.00 38.73  ? 30  LEU H O   1 
ATOM   18824 C CB  . LEU G 2 12  ? 2.905   -13.619 -0.122 1.00 38.54  ? 30  LEU H CB  1 
ATOM   18825 C CG  . LEU G 2 12  ? 2.228   -13.918 -1.454 1.00 38.54  ? 30  LEU H CG  1 
ATOM   18826 C CD1 . LEU G 2 12  ? 1.811   -12.629 -2.140 1.00 38.54  ? 30  LEU H CD1 1 
ATOM   18827 C CD2 . LEU G 2 12  ? 3.156   -14.733 -2.336 1.00 38.54  ? 30  LEU H CD2 1 
ATOM   18828 N N   . VAL G 2 13  ? -0.409  -13.334 0.768  1.00 38.80  ? 31  VAL H N   1 
ATOM   18829 C CA  . VAL G 2 13  ? -1.676  -14.036 0.846  1.00 38.80  ? 31  VAL H CA  1 
ATOM   18830 C C   . VAL G 2 13  ? -2.485  -13.865 -0.430 1.00 38.80  ? 31  VAL H C   1 
ATOM   18831 O O   . VAL G 2 13  ? -2.586  -12.763 -0.951 1.00 38.80  ? 31  VAL H O   1 
ATOM   18832 C CB  . VAL G 2 13  ? -2.486  -13.512 2.046  1.00 36.59  ? 31  VAL H CB  1 
ATOM   18833 C CG1 . VAL G 2 13  ? -3.910  -14.030 2.033  1.00 36.59  ? 31  VAL H CG1 1 
ATOM   18834 C CG2 . VAL G 2 13  ? -1.793  -13.879 3.343  1.00 36.59  ? 31  VAL H CG2 1 
ATOM   18835 N N   . GLN G 2 14  ? -3.039  -14.954 -0.953 1.00 41.79  ? 32  GLN H N   1 
ATOM   18836 C CA  . GLN G 2 14  ? -3.876  -14.867 -2.145 1.00 41.79  ? 32  GLN H CA  1 
ATOM   18837 C C   . GLN G 2 14  ? -5.210  -14.223 -1.783 1.00 41.79  ? 32  GLN H C   1 
ATOM   18838 O O   . GLN G 2 14  ? -5.662  -14.332 -0.651 1.00 41.79  ? 32  GLN H O   1 
ATOM   18839 C CB  . GLN G 2 14  ? -4.072  -16.234 -2.790 1.00 47.06  ? 32  GLN H CB  1 
ATOM   18840 C CG  . GLN G 2 14  ? -4.156  -17.384 -1.809 1.00 47.06  ? 32  GLN H CG  1 
ATOM   18841 C CD  . GLN G 2 14  ? -3.958  -18.723 -2.489 1.00 47.06  ? 32  GLN H CD  1 
ATOM   18842 O OE1 . GLN G 2 14  ? -3.515  -18.788 -3.635 1.00 47.06  ? 32  GLN H OE1 1 
ATOM   18843 N NE2 . GLN G 2 14  ? -4.282  -19.800 -1.783 1.00 47.06  ? 32  GLN H NE2 1 
ATOM   18844 N N   . PRO G 2 15  ? -5.857  -13.563 -2.748 1.00 42.78  ? 33  PRO H N   1 
ATOM   18845 C CA  . PRO G 2 15  ? -7.119  -12.881 -2.454 1.00 42.78  ? 33  PRO H CA  1 
ATOM   18846 C C   . PRO G 2 15  ? -8.215  -13.828 -1.993 1.00 42.78  ? 33  PRO H C   1 
ATOM   18847 O O   . PRO G 2 15  ? -8.302  -14.954 -2.465 1.00 42.78  ? 33  PRO H O   1 
ATOM   18848 C CB  . PRO G 2 15  ? -7.504  -12.266 -3.802 1.00 43.36  ? 33  PRO H CB  1 
ATOM   18849 C CG  . PRO G 2 15  ? -6.231  -12.185 -4.567 1.00 43.36  ? 33  PRO H CG  1 
ATOM   18850 C CD  . PRO G 2 15  ? -5.456  -13.396 -4.152 1.00 43.36  ? 33  PRO H CD  1 
ATOM   18851 N N   . GLY G 2 16  ? -9.015  -13.380 -1.034 1.00 40.59  ? 34  GLY H N   1 
ATOM   18852 C CA  . GLY G 2 16  ? -10.082 -14.190 -0.486 1.00 40.59  ? 34  GLY H CA  1 
ATOM   18853 C C   . GLY G 2 16  ? -9.641  -14.836 0.812  1.00 40.59  ? 34  GLY H C   1 
ATOM   18854 O O   . GLY G 2 16  ? -10.449 -15.070 1.704  1.00 40.59  ? 34  GLY H O   1 
ATOM   18855 N N   . LYS G 2 17  ? -8.352  -15.141 0.904  1.00 38.66  ? 35  LYS H N   1 
ATOM   18856 C CA  . LYS G 2 17  ? -7.778  -15.753 2.099  1.00 38.66  ? 35  LYS H CA  1 
ATOM   18857 C C   . LYS G 2 17  ? -7.659  -14.740 3.227  1.00 38.66  ? 35  LYS H C   1 
ATOM   18858 O O   . LYS G 2 17  ? -7.630  -13.543 2.984  1.00 38.66  ? 35  LYS H O   1 
ATOM   18859 C CB  . LYS G 2 17  ? -6.416  -16.374 1.796  1.00 46.96  ? 35  LYS H CB  1 
ATOM   18860 C CG  . LYS G 2 17  ? -6.456  -17.428 0.705  1.00 46.96  ? 35  LYS H CG  1 
ATOM   18861 C CD  . LYS G 2 17  ? -7.583  -18.412 0.954  1.00 46.96  ? 35  LYS H CD  1 
ATOM   18862 C CE  . LYS G 2 17  ? -8.062  -19.043 -0.342 1.00 46.96  ? 35  LYS H CE  1 
ATOM   18863 N NZ  . LYS G 2 17  ? -9.260  -19.899 -0.123 1.00 46.96  ? 35  LYS H NZ  1 
ATOM   18864 N N   . SER G 2 18  ? -7.608  -15.225 4.462  1.00 32.54  ? 36  SER H N   1 
ATOM   18865 C CA  . SER G 2 18  ? -7.499  -14.362 5.629  1.00 32.54  ? 36  SER H CA  1 
ATOM   18866 C C   . SER G 2 18  ? -6.282  -14.696 6.478  1.00 32.54  ? 36  SER H C   1 
ATOM   18867 O O   . SER G 2 18  ? -6.006  -15.863 6.727  1.00 32.54  ? 36  SER H O   1 
ATOM   18868 C CB  . SER G 2 18  ? -8.756  -14.488 6.486  1.00 30.51  ? 36  SER H CB  1 
ATOM   18869 O OG  . SER G 2 18  ? -8.815  -15.755 7.113  1.00 30.51  ? 36  SER H OG  1 
ATOM   18870 N N   . LEU G 2 19  ? -5.565  -13.671 6.932  1.00 27.00  ? 37  LEU H N   1 
ATOM   18871 C CA  . LEU G 2 19  ? -4.380  -13.858 7.770  1.00 27.00  ? 37  LEU H CA  1 
ATOM   18872 C C   . LEU G 2 19  ? -4.462  -13.025 9.044  1.00 27.00  ? 37  LEU H C   1 
ATOM   18873 O O   . LEU G 2 19  ? -5.203  -12.057 9.107  1.00 27.00  ? 37  LEU H O   1 
ATOM   18874 C CB  . LEU G 2 19  ? -3.089  -13.556 7.009  1.00 28.26  ? 37  LEU H CB  1 
ATOM   18875 C CG  . LEU G 2 19  ? -2.831  -12.170 6.425  1.00 28.26  ? 37  LEU H CG  1 
ATOM   18876 C CD1 . LEU G 2 19  ? -3.101  -11.088 7.450  1.00 28.26  ? 37  LEU H CD1 1 
ATOM   18877 C CD2 . LEU G 2 19  ? -1.391  -12.089 5.955  1.00 28.26  ? 37  LEU H CD2 1 
ATOM   18878 N N   . ARG G 2 20  ? -3.710  -13.419 10.064 1.00 25.68  ? 38  ARG H N   1 
ATOM   18879 C CA  . ARG G 2 20  ? -3.730  -12.726 11.346 1.00 25.68  ? 38  ARG H CA  1 
ATOM   18880 C C   . ARG G 2 20  ? -2.399  -12.081 11.710 1.00 25.68  ? 38  ARG H C   1 
ATOM   18881 O O   . ARG G 2 20  ? -1.357  -12.712 11.639 1.00 25.68  ? 38  ARG H O   1 
ATOM   18882 C CB  . ARG G 2 20  ? -4.129  -13.706 12.442 1.00 30.27  ? 38  ARG H CB  1 
ATOM   18883 C CG  . ARG G 2 20  ? -4.571  -13.052 13.732 1.00 30.27  ? 38  ARG H CG  1 
ATOM   18884 C CD  . ARG G 2 20  ? -4.428  -14.021 14.884 1.00 30.27  ? 38  ARG H CD  1 
ATOM   18885 N NE  . ARG G 2 20  ? -5.465  -13.831 15.886 1.00 30.27  ? 38  ARG H NE  1 
ATOM   18886 C CZ  . ARG G 2 20  ? -5.488  -14.459 17.053 1.00 30.27  ? 38  ARG H CZ  1 
ATOM   18887 N NH1 . ARG G 2 20  ? -4.521  -15.310 17.367 1.00 30.27  ? 38  ARG H NH1 1 
ATOM   18888 N NH2 . ARG G 2 20  ? -6.473  -14.233 17.910 1.00 30.27  ? 38  ARG H NH2 1 
ATOM   18889 N N   . LEU G 2 21  ? -2.452  -10.823 12.127 1.00 22.70  ? 39  LEU H N   1 
ATOM   18890 C CA  . LEU G 2 21  ? -1.273  -10.058 12.509 1.00 22.70  ? 39  LEU H CA  1 
ATOM   18891 C C   . LEU G 2 21  ? -1.197  -9.911  14.014 1.00 22.70  ? 39  LEU H C   1 
ATOM   18892 O O   . LEU G 2 21  ? -2.214  -9.850  14.685 1.00 22.70  ? 39  LEU H O   1 
ATOM   18893 C CB  . LEU G 2 21  ? -1.332  -8.664  11.898 1.00 22.09  ? 39  LEU H CB  1 
ATOM   18894 C CG  . LEU G 2 21  ? -0.657  -8.405  10.560 1.00 22.09  ? 39  LEU H CG  1 
ATOM   18895 C CD1 . LEU G 2 21  ? -0.967  -9.510  9.574  1.00 22.09  ? 39  LEU H CD1 1 
ATOM   18896 C CD2 . LEU G 2 21  ? -1.085  -7.056  10.019 1.00 22.09  ? 39  LEU H CD2 1 
ATOM   18897 N N   . SER G 2 22  ? 0.014   -9.892  14.549 1.00 22.59  ? 40  SER H N   1 
ATOM   18898 C CA  . SER G 2 22  ? 0.201   -9.723  15.982 1.00 22.59  ? 40  SER H CA  1 
ATOM   18899 C C   . SER G 2 22  ? 1.270   -8.683  16.281 1.00 22.59  ? 40  SER H C   1 
ATOM   18900 O O   . SER G 2 22  ? 2.189   -8.493  15.504 1.00 22.59  ? 40  SER H O   1 
ATOM   18901 C CB  . SER G 2 22  ? 0.538   -11.051 16.650 1.00 26.21  ? 40  SER H CB  1 
ATOM   18902 O OG  . SER G 2 22  ? 1.207   -11.913 15.753 1.00 26.21  ? 40  SER H OG  1 
ATOM   18903 N N   . CYS G 2 23  ? 1.109   -7.975  17.389 1.00 22.23  ? 41  CYS H N   1 
ATOM   18904 C CA  . CYS G 2 23  ? 2.059   -6.964  17.818 1.00 22.23  ? 41  CYS H CA  1 
ATOM   18905 C C   . CYS G 2 23  ? 2.420   -7.246  19.271 1.00 22.23  ? 41  CYS H C   1 
ATOM   18906 O O   . CYS G 2 23  ? 1.537   -7.400  20.095 1.00 22.23  ? 41  CYS H O   1 
ATOM   18907 C CB  . CYS G 2 23  ? 1.412   -5.593  17.666 1.00 23.14  ? 41  CYS H CB  1 
ATOM   18908 S SG  . CYS G 2 23  ? 2.318   -4.167  18.293 1.00 23.14  ? 41  CYS H SG  1 
ATOM   18909 N N   . ALA G 2 24  ? 3.705   -7.318  19.595 1.00 22.73  ? 42  ALA H N   1 
ATOM   18910 C CA  . ALA G 2 24  ? 4.125   -7.580  20.970 1.00 22.73  ? 42  ALA H CA  1 
ATOM   18911 C C   . ALA G 2 24  ? 4.601   -6.283  21.580 1.00 22.73  ? 42  ALA H C   1 
ATOM   18912 O O   . ALA G 2 24  ? 5.576   -5.704  21.125 1.00 22.73  ? 42  ALA H O   1 
ATOM   18913 C CB  . ALA G 2 24  ? 5.223   -8.620  21.007 1.00 21.19  ? 42  ALA H CB  1 
ATOM   18914 N N   . ALA G 2 25  ? 3.931   -5.835  22.630 1.00 24.75  ? 43  ALA H N   1 
ATOM   18915 C CA  . ALA G 2 25  ? 4.272   -4.552  23.227 1.00 24.75  ? 43  ALA H CA  1 
ATOM   18916 C C   . ALA G 2 25  ? 5.067   -4.766  24.505 1.00 24.75  ? 43  ALA H C   1 
ATOM   18917 O O   . ALA G 2 25  ? 4.797   -5.705  25.259 1.00 24.75  ? 43  ALA H O   1 
ATOM   18918 C CB  . ALA G 2 25  ? 3.012   -3.742  23.524 1.00 19.99  ? 43  ALA H CB  1 
ATOM   18919 N N   . SER G 2 26  ? 6.044   -3.894  24.741 1.00 27.67  ? 44  SER H N   1 
ATOM   18920 C CA  . SER G 2 26  ? 6.859   -3.948  25.943 1.00 27.67  ? 44  SER H CA  1 
ATOM   18921 C C   . SER G 2 26  ? 7.374   -2.553  26.258 1.00 27.67  ? 44  SER H C   1 
ATOM   18922 O O   . SER G 2 26  ? 7.507   -1.706  25.374 1.00 27.67  ? 44  SER H O   1 
ATOM   18923 C CB  . SER G 2 26  ? 8.029   -4.923  25.789 1.00 33.00  ? 44  SER H CB  1 
ATOM   18924 O OG  . SER G 2 26  ? 8.834   -4.935  26.953 1.00 33.00  ? 44  SER H OG  1 
ATOM   18925 N N   . GLY G 2 27  ? 7.661   -2.323  27.535 1.00 24.88  ? 45  GLY H N   1 
ATOM   18926 C CA  . GLY G 2 27  ? 8.194   -1.055  27.981 1.00 24.88  ? 45  GLY H CA  1 
ATOM   18927 C C   . GLY G 2 27  ? 7.176   -0.082  28.531 1.00 24.88  ? 45  GLY H C   1 
ATOM   18928 O O   . GLY G 2 27  ? 7.552   1.039   28.895 1.00 24.88  ? 45  GLY H O   1 
ATOM   18929 N N   . PHE G 2 28  ? 5.904   -0.465  28.596 1.00 18.70  ? 46  PHE H N   1 
ATOM   18930 C CA  . PHE G 2 28  ? 4.854   0.409   29.094 1.00 18.70  ? 46  PHE H CA  1 
ATOM   18931 C C   . PHE G 2 28  ? 3.710   -0.464  29.581 1.00 18.70  ? 46  PHE H C   1 
ATOM   18932 O O   . PHE G 2 28  ? 3.664   -1.663  29.303 1.00 18.70  ? 46  PHE H O   1 
ATOM   18933 C CB  . PHE G 2 28  ? 4.374   1.386   28.016 1.00 15.86  ? 46  PHE H CB  1 
ATOM   18934 C CG  . PHE G 2 28  ? 3.666   0.725   26.870 1.00 15.86  ? 46  PHE H CG  1 
ATOM   18935 C CD1 . PHE G 2 28  ? 2.289   0.634   26.855 1.00 15.86  ? 46  PHE H CD1 1 
ATOM   18936 C CD2 . PHE G 2 28  ? 4.376   0.166   25.827 1.00 15.86  ? 46  PHE H CD2 1 
ATOM   18937 C CE1 . PHE G 2 28  ? 1.636   0.022   25.813 1.00 15.86  ? 46  PHE H CE1 1 
ATOM   18938 C CE2 . PHE G 2 28  ? 3.725   -0.447  24.784 1.00 15.86  ? 46  PHE H CE2 1 
ATOM   18939 C CZ  . PHE G 2 28  ? 2.354   -0.520  24.779 1.00 15.86  ? 46  PHE H CZ  1 
ATOM   18940 N N   . SER G 2 29  ? 2.788   0.141   30.320 1.00 15.14  ? 47  SER H N   1 
ATOM   18941 C CA  . SER G 2 29  ? 1.608   -0.593  30.768 1.00 15.14  ? 47  SER H CA  1 
ATOM   18942 C C   . SER G 2 29  ? 0.654   -0.698  29.588 1.00 15.14  ? 47  SER H C   1 
ATOM   18943 O O   . SER G 2 29  ? 0.140   0.305   29.098 1.00 15.14  ? 47  SER H O   1 
ATOM   18944 C CB  . SER G 2 29  ? 0.958   0.113   31.951 1.00 15.73  ? 47  SER H CB  1 
ATOM   18945 O OG  . SER G 2 29  ? -0.200  -0.574  32.384 1.00 15.73  ? 47  SER H OG  1 
ATOM   18946 N N   . PHE G 2 30  ? 0.385   -1.926  29.147 1.00 13.80  ? 48  PHE H N   1 
ATOM   18947 C CA  . PHE G 2 30  ? -0.272  -2.116  27.859 1.00 13.80  ? 48  PHE H CA  1 
ATOM   18948 C C   . PHE G 2 30  ? -1.762  -1.816  27.935 1.00 13.80  ? 48  PHE H C   1 
ATOM   18949 O O   . PHE G 2 30  ? -2.309  -1.117  27.076 1.00 13.80  ? 48  PHE H O   1 
ATOM   18950 C CB  . PHE G 2 30  ? -0.029  -3.543  27.370 1.00 14.39  ? 48  PHE H CB  1 
ATOM   18951 C CG  . PHE G 2 30  ? -0.695  -3.864  26.072 1.00 14.39  ? 48  PHE H CG  1 
ATOM   18952 C CD1 . PHE G 2 30  ? -0.139  -3.456  24.880 1.00 14.39  ? 48  PHE H CD1 1 
ATOM   18953 C CD2 . PHE G 2 30  ? -1.861  -4.599  26.041 1.00 14.39  ? 48  PHE H CD2 1 
ATOM   18954 C CE1 . PHE G 2 30  ? -0.743  -3.754  23.684 1.00 14.39  ? 48  PHE H CE1 1 
ATOM   18955 C CE2 . PHE G 2 30  ? -2.468  -4.899  24.847 1.00 14.39  ? 48  PHE H CE2 1 
ATOM   18956 C CZ  . PHE G 2 30  ? -1.907  -4.479  23.667 1.00 14.39  ? 48  PHE H CZ  1 
ATOM   18957 N N   . SER G 2 31  ? -2.434  -2.326  28.964 1.00 16.44  ? 49  SER H N   1 
ATOM   18958 C CA  . SER G 2 31  ? -3.881  -2.207  29.070 1.00 16.44  ? 49  SER H CA  1 
ATOM   18959 C C   . SER G 2 31  ? -4.355  -0.784  29.323 1.00 16.44  ? 49  SER H C   1 
ATOM   18960 O O   . SER G 2 31  ? -5.565  -0.543  29.297 1.00 16.44  ? 49  SER H O   1 
ATOM   18961 C CB  . SER G 2 31  ? -4.388  -3.120  30.181 1.00 18.14  ? 49  SER H CB  1 
ATOM   18962 O OG  . SER G 2 31  ? -3.832  -2.749  31.427 1.00 18.14  ? 49  SER H OG  1 
ATOM   18963 N N   . ASN G 2 32  ? -3.427  0.144   29.520 1.00 14.74  ? 50  ASN H N   1 
ATOM   18964 C CA  . ASN G 2 32  ? -3.787  1.528   29.795 1.00 14.74  ? 50  ASN H CA  1 
ATOM   18965 C C   . ASN G 2 32  ? -3.668  2.481   28.617 1.00 14.74  ? 50  ASN H C   1 
ATOM   18966 O O   . ASN G 2 32  ? -3.722  3.685   28.792 1.00 14.74  ? 50  ASN H O   1 
ATOM   18967 C CB  . ASN G 2 32  ? -2.985  2.048   30.977 1.00 15.40  ? 50  ASN H CB  1 
ATOM   18968 C CG  . ASN G 2 32  ? -3.505  1.527   32.291 1.00 15.40  ? 50  ASN H CG  1 
ATOM   18969 O OD1 . ASN G 2 32  ? -4.615  1.845   32.698 1.00 15.40  ? 50  ASN H OD1 1 
ATOM   18970 N ND2 . ASN G 2 32  ? -2.707  0.717   32.959 1.00 15.40  ? 50  ASN H ND2 1 
ATOM   18971 N N   . TYR G 2 33  ? -3.490  1.939   27.422 1.00 11.85  ? 51  TYR H N   1 
ATOM   18972 C CA  . TYR G 2 33  ? -3.392  2.747   26.222 1.00 11.85  ? 51  TYR H CA  1 
ATOM   18973 C C   . TYR G 2 33  ? -4.207  2.074   25.152 1.00 11.85  ? 51  TYR H C   1 
ATOM   18974 O O   . TYR G 2 33  ? -4.282  0.857   25.111 1.00 11.85  ? 51  TYR H O   1 
ATOM   18975 C CB  . TYR G 2 33  ? -1.948  2.844   25.747 1.00 12.44  ? 51  TYR H CB  1 
ATOM   18976 C CG  . TYR G 2 33  ? -1.010  3.466   26.740 1.00 12.44  ? 51  TYR H CG  1 
ATOM   18977 C CD1 . TYR G 2 33  ? -0.818  4.827   26.775 1.00 12.44  ? 51  TYR H CD1 1 
ATOM   18978 C CD2 . TYR G 2 33  ? -0.312  2.684   27.640 1.00 12.44  ? 51  TYR H CD2 1 
ATOM   18979 C CE1 . TYR G 2 33  ? 0.041   5.395   27.684 1.00 12.44  ? 51  TYR H CE1 1 
ATOM   18980 C CE2 . TYR G 2 33  ? 0.545   3.246   28.553 1.00 12.44  ? 51  TYR H CE2 1 
ATOM   18981 C CZ  . TYR G 2 33  ? 0.716   4.599   28.568 1.00 12.44  ? 51  TYR H CZ  1 
ATOM   18982 O OH  . TYR G 2 33  ? 1.574   5.147   29.477 1.00 12.44  ? 51  TYR H OH  1 
ATOM   18983 N N   . ALA G 2 34  ? -4.788  2.852   24.257 1.00 10.60  ? 52  ALA H N   1 
ATOM   18984 C CA  . ALA G 2 34  ? -5.580  2.261   23.207 1.00 10.60  ? 52  ALA H CA  1 
ATOM   18985 C C   . ALA G 2 34  ? -4.705  2.131   21.991 1.00 10.60  ? 52  ALA H C   1 
ATOM   18986 O O   . ALA G 2 34  ? -4.213  3.110   21.468 1.00 10.60  ? 52  ALA H O   1 
ATOM   18987 C CB  . ALA G 2 34  ? -6.781  3.126   22.902 1.00 11.01  ? 52  ALA H CB  1 
ATOM   18988 N N   . MET G 2 35  ? -4.499  0.901   21.555 1.00 10.80  ? 53  MET H N   1 
ATOM   18989 C CA  . MET G 2 35  ? -3.680  0.617   20.396 1.00 10.80  ? 53  MET H CA  1 
ATOM   18990 C C   . MET G 2 35  ? -4.443  0.847   19.113 1.00 10.80  ? 53  MET H C   1 
ATOM   18991 O O   . MET G 2 35  ? -5.663  0.900   19.111 1.00 10.80  ? 53  MET H O   1 
ATOM   18992 C CB  . MET G 2 35  ? -3.170  -0.809  20.462 1.00 15.11  ? 53  MET H CB  1 
ATOM   18993 C CG  . MET G 2 35  ? -2.564  -1.141  21.806 1.00 15.11  ? 53  MET H CG  1 
ATOM   18994 S SD  . MET G 2 35  ? -1.145  -0.108  22.173 1.00 15.11  ? 53  MET H SD  1 
ATOM   18995 C CE  . MET G 2 35  ? 0.049   -0.834  21.061 1.00 15.11  ? 53  MET H CE  1 
ATOM   18996 N N   . SER G 2 36  ? -3.718  0.915   18.002 1.00 11.03  ? 54  SER H N   1 
ATOM   18997 C CA  . SER G 2 36  ? -4.329  1.081   16.689 1.00 11.03  ? 54  SER H CA  1 
ATOM   18998 C C   . SER G 2 36  ? -3.440  0.528   15.583 1.00 11.03  ? 54  SER H C   1 
ATOM   18999 O O   . SER G 2 36  ? -2.256  0.353   15.778 1.00 11.03  ? 54  SER H O   1 
ATOM   19000 C CB  . SER G 2 36  ? -4.668  2.540   16.421 1.00 11.21  ? 54  SER H CB  1 
ATOM   19001 O OG  . SER G 2 36  ? -3.601  3.378   16.788 1.00 11.21  ? 54  SER H OG  1 
ATOM   19002 N N   . TRP G 2 37  ? -4.022  0.228   14.430 1.00 10.75  ? 55  TRP H N   1 
ATOM   19003 C CA  . TRP G 2 37  ? -3.270  -0.286  13.295 1.00 10.75  ? 55  TRP H CA  1 
ATOM   19004 C C   . TRP G 2 37  ? -3.347  0.720   12.168 1.00 10.75  ? 55  TRP H C   1 
ATOM   19005 O O   . TRP G 2 37  ? -4.422  1.163   11.801 1.00 10.75  ? 55  TRP H O   1 
ATOM   19006 C CB  . TRP G 2 37  ? -3.850  -1.607  12.789 1.00 14.33  ? 55  TRP H CB  1 
ATOM   19007 C CG  . TRP G 2 37  ? -3.550  -2.816  13.617 1.00 14.33  ? 55  TRP H CG  1 
ATOM   19008 C CD1 . TRP G 2 37  ? -4.343  -3.368  14.570 1.00 14.33  ? 55  TRP H CD1 1 
ATOM   19009 C CD2 . TRP G 2 37  ? -2.387  -3.643  13.538 1.00 14.33  ? 55  TRP H CD2 1 
ATOM   19010 N NE1 . TRP G 2 37  ? -3.742  -4.474  15.104 1.00 14.33  ? 55  TRP H NE1 1 
ATOM   19011 C CE2 . TRP G 2 37  ? -2.537  -4.664  14.487 1.00 14.33  ? 55  TRP H CE2 1 
ATOM   19012 C CE3 . TRP G 2 37  ? -1.227  -3.612  12.766 1.00 14.33  ? 55  TRP H CE3 1 
ATOM   19013 C CZ2 . TRP G 2 37  ? -1.576  -5.641  14.686 1.00 14.33  ? 55  TRP H CZ2 1 
ATOM   19014 C CZ3 . TRP G 2 37  ? -0.277  -4.583  12.964 1.00 14.33  ? 55  TRP H CZ3 1 
ATOM   19015 C CH2 . TRP G 2 37  ? -0.455  -5.583  13.916 1.00 14.33  ? 55  TRP H CH2 1 
ATOM   19016 N N   . VAL G 2 38  ? -2.204  1.094   11.624 1.00 14.53  ? 56  VAL H N   1 
ATOM   19017 C CA  . VAL G 2 38  ? -2.169  2.028   10.513 1.00 14.53  ? 56  VAL H CA  1 
ATOM   19018 C C   . VAL G 2 38  ? -1.420  1.376   9.363  1.00 14.53  ? 56  VAL H C   1 
ATOM   19019 O O   . VAL G 2 38  ? -0.367  0.803   9.563  1.00 14.53  ? 56  VAL H O   1 
ATOM   19020 C CB  . VAL G 2 38  ? -1.569  3.376   10.924 1.00 13.25  ? 56  VAL H CB  1 
ATOM   19021 C CG1 . VAL G 2 38  ? -0.787  3.240   12.211 1.00 13.25  ? 56  VAL H CG1 1 
ATOM   19022 C CG2 . VAL G 2 38  ? -0.731  3.961   9.811  1.00 13.25  ? 56  VAL H CG2 1 
ATOM   19023 N N   . ARG G 2 39  ? -1.973  1.453   8.163  1.00 18.61  ? 57  ARG H N   1 
ATOM   19024 C CA  . ARG G 2 39  ? -1.369  0.811   7.006  1.00 18.61  ? 57  ARG H CA  1 
ATOM   19025 C C   . ARG G 2 39  ? -0.912  1.791   5.943  1.00 18.61  ? 57  ARG H C   1 
ATOM   19026 O O   . ARG G 2 39  ? -1.630  2.712   5.599  1.00 18.61  ? 57  ARG H O   1 
ATOM   19027 C CB  . ARG G 2 39  ? -2.389  -0.130  6.370  1.00 23.87  ? 57  ARG H CB  1 
ATOM   19028 C CG  . ARG G 2 39  ? -3.028  0.450   5.124  1.00 23.87  ? 57  ARG H CG  1 
ATOM   19029 C CD  . ARG G 2 39  ? -4.524  0.239   5.062  1.00 23.87  ? 57  ARG H CD  1 
ATOM   19030 N NE  . ARG G 2 39  ? -4.874  -1.095  4.612  1.00 23.87  ? 57  ARG H NE  1 
ATOM   19031 C CZ  . ARG G 2 39  ? -5.985  -1.380  3.950  1.00 23.87  ? 57  ARG H CZ  1 
ATOM   19032 N NH1 . ARG G 2 39  ? -6.235  -2.621  3.580  1.00 23.87  ? 57  ARG H NH1 1 
ATOM   19033 N NH2 . ARG G 2 39  ? -6.840  -0.422  3.654  1.00 23.87  ? 57  ARG H NH2 1 
ATOM   19034 N N   . GLN G 2 40  ? 0.269   1.565   5.399  1.00 22.02  ? 58  GLN H N   1 
ATOM   19035 C CA  . GLN G 2 40  ? 0.767   2.424   4.344  1.00 22.02  ? 58  GLN H CA  1 
ATOM   19036 C C   . GLN G 2 40  ? 0.997   1.645   3.061  1.00 22.02  ? 58  GLN H C   1 
ATOM   19037 O O   . GLN G 2 40  ? 1.879   0.800   2.991  1.00 22.02  ? 58  GLN H O   1 
ATOM   19038 C CB  . GLN G 2 40  ? 2.060   3.107   4.758  1.00 23.02  ? 58  GLN H CB  1 
ATOM   19039 C CG  . GLN G 2 40  ? 2.720   3.830   3.607  1.00 23.02  ? 58  GLN H CG  1 
ATOM   19040 C CD  . GLN G 2 40  ? 3.738   4.839   4.063  1.00 23.02  ? 58  GLN H CD  1 
ATOM   19041 O OE1 . GLN G 2 40  ? 4.433   4.633   5.046  1.00 23.02  ? 58  GLN H OE1 1 
ATOM   19042 N NE2 . GLN G 2 40  ? 3.834   5.937   3.343  1.00 23.02  ? 58  GLN H NE2 1 
ATOM   19043 N N   . ALA G 2 41  ? 0.195   1.936   2.043  1.00 28.74  ? 59  ALA H N   1 
ATOM   19044 C CA  . ALA G 2 41  ? 0.327   1.293   0.744  1.00 28.74  ? 59  ALA H CA  1 
ATOM   19045 C C   . ALA G 2 41  ? 1.597   1.794   0.071  1.00 28.74  ? 59  ALA H C   1 
ATOM   19046 O O   . ALA G 2 41  ? 2.008   2.932   0.300  1.00 28.74  ? 59  ALA H O   1 
ATOM   19047 C CB  . ALA G 2 41  ? -0.884  1.594   -0.116 1.00 29.49  ? 59  ALA H CB  1 
ATOM   19048 N N   . PRO G 2 42  ? 2.215   0.965   -0.786 1.00 32.07  ? 60  PRO H N   1 
ATOM   19049 C CA  . PRO G 2 42  ? 3.462   1.405   -1.422 1.00 32.07  ? 60  PRO H CA  1 
ATOM   19050 C C   . PRO G 2 42  ? 3.239   2.671   -2.237 1.00 32.07  ? 60  PRO H C   1 
ATOM   19051 O O   . PRO G 2 42  ? 2.317   2.740   -3.041 1.00 32.07  ? 60  PRO H O   1 
ATOM   19052 C CB  . PRO G 2 42  ? 3.807   0.239   -2.349 1.00 32.41  ? 60  PRO H CB  1 
ATOM   19053 C CG  . PRO G 2 42  ? 3.093   -0.937  -1.774 1.00 32.41  ? 60  PRO H CG  1 
ATOM   19054 C CD  . PRO G 2 42  ? 1.823   -0.390  -1.202 1.00 32.41  ? 60  PRO H CD  1 
ATOM   19055 N N   . GLY G 2 43  ? 4.107   3.658   -2.034 1.00 31.79  ? 61  GLY H N   1 
ATOM   19056 C CA  . GLY G 2 43  ? 3.990   4.949   -2.689 1.00 31.79  ? 61  GLY H CA  1 
ATOM   19057 C C   . GLY G 2 43  ? 2.703   5.687   -2.346 1.00 31.79  ? 61  GLY H C   1 
ATOM   19058 O O   . GLY G 2 43  ? 2.141   6.386   -3.186 1.00 31.79  ? 61  GLY H O   1 
ATOM   19059 N N   . LYS G 2 44  ? 2.241   5.537   -1.106 1.00 29.13  ? 62  LYS H N   1 
ATOM   19060 C CA  . LYS G 2 44  ? 1.008   6.161   -0.640 1.00 29.13  ? 62  LYS H CA  1 
ATOM   19061 C C   . LYS G 2 44  ? 1.129   6.635   0.798  1.00 29.13  ? 62  LYS H C   1 
ATOM   19062 O O   . LYS G 2 44  ? 1.997   6.189   1.538  1.00 29.13  ? 62  LYS H O   1 
ATOM   19063 C CB  . LYS G 2 44  ? -0.160  5.187   -0.738 1.00 36.56  ? 62  LYS H CB  1 
ATOM   19064 C CG  . LYS G 2 44  ? -0.573  4.814   -2.146 1.00 36.56  ? 62  LYS H CG  1 
ATOM   19065 C CD  . LYS G 2 44  ? -1.186  5.997   -2.865 1.00 36.56  ? 62  LYS H CD  1 
ATOM   19066 C CE  . LYS G 2 44  ? -2.048  5.532   -4.022 1.00 36.56  ? 62  LYS H CE  1 
ATOM   19067 N NZ  . LYS G 2 44  ? -3.080  4.570   -3.551 1.00 36.56  ? 62  LYS H NZ  1 
ATOM   19068 N N   . GLY G 2 45  ? 0.251   7.550   1.182  1.00 22.55  ? 63  GLY H N   1 
ATOM   19069 C CA  . GLY G 2 45  ? 0.222   8.098   2.523  1.00 22.55  ? 63  GLY H CA  1 
ATOM   19070 C C   . GLY G 2 45  ? -0.334  7.133   3.550  1.00 22.55  ? 63  GLY H C   1 
ATOM   19071 O O   . GLY G 2 45  ? -0.950  6.135   3.204  1.00 22.55  ? 63  GLY H O   1 
ATOM   19072 N N   . LEU G 2 46  ? -0.090  7.426   4.819  1.00 17.32  ? 64  LEU H N   1 
ATOM   19073 C CA  . LEU G 2 46  ? -0.562  6.604   5.919  1.00 17.32  ? 64  LEU H CA  1 
ATOM   19074 C C   . LEU G 2 46  ? -2.080  6.567   5.979  1.00 17.32  ? 64  LEU H C   1 
ATOM   19075 O O   . LEU G 2 46  ? -2.737  7.551   5.686  1.00 17.32  ? 64  LEU H O   1 
ATOM   19076 C CB  . LEU G 2 46  ? -0.044  7.177   7.230  1.00 17.76  ? 64  LEU H CB  1 
ATOM   19077 C CG  . LEU G 2 46  ? 1.465   7.237   7.415  1.00 17.76  ? 64  LEU H CG  1 
ATOM   19078 C CD1 . LEU G 2 46  ? 1.823   8.253   8.479  1.00 17.76  ? 64  LEU H CD1 1 
ATOM   19079 C CD2 . LEU G 2 46  ? 1.997   5.868   7.787  1.00 17.76  ? 64  LEU H CD2 1 
ATOM   19080 N N   . GLU G 2 47  ? -2.633  5.419   6.342  1.00 16.75  ? 65  GLU H N   1 
ATOM   19081 C CA  . GLU G 2 47  ? -4.075  5.263   6.464  1.00 16.75  ? 65  GLU H CA  1 
ATOM   19082 C C   . GLU G 2 47  ? -4.411  4.484   7.722  1.00 16.75  ? 65  GLU H C   1 
ATOM   19083 O O   . GLU G 2 47  ? -3.927  3.380   7.925  1.00 16.75  ? 65  GLU H O   1 
ATOM   19084 C CB  . GLU G 2 47  ? -4.663  4.545   5.260  1.00 21.50  ? 65  GLU H CB  1 
ATOM   19085 C CG  . GLU G 2 47  ? -6.133  4.222   5.451  1.00 21.50  ? 65  GLU H CG  1 
ATOM   19086 C CD  . GLU G 2 47  ? -6.657  3.216   4.454  1.00 21.50  ? 65  GLU H CD  1 
ATOM   19087 O OE1 . GLU G 2 47  ? -5.877  2.764   3.593  1.00 21.50  ? 65  GLU H OE1 1 
ATOM   19088 O OE2 . GLU G 2 47  ? -7.853  2.875   4.532  1.00 21.50  ? 65  GLU H OE2 1 
ATOM   19089 N N   . TRP G 2 48  ? -5.258  5.058   8.560  1.00 14.46  ? 66  TRP H N   1 
ATOM   19090 C CA  . TRP G 2 48  ? -5.641  4.433   9.816  1.00 14.46  ? 66  TRP H CA  1 
ATOM   19091 C C   . TRP G 2 48  ? -6.776  3.448   9.576  1.00 14.46  ? 66  TRP H C   1 
ATOM   19092 O O   . TRP G 2 48  ? -7.831  3.823   9.059  1.00 14.46  ? 66  TRP H O   1 
ATOM   19093 C CB  . TRP G 2 48  ? -6.064  5.516   10.805 1.00 11.92  ? 66  TRP H CB  1 
ATOM   19094 C CG  . TRP G 2 48  ? -6.492  5.062   12.161 1.00 11.92  ? 66  TRP H CG  1 
ATOM   19095 C CD1 . TRP G 2 48  ? -5.701  4.893   13.252 1.00 11.92  ? 66  TRP H CD1 1 
ATOM   19096 C CD2 . TRP G 2 48  ? -7.827  4.762   12.583 1.00 11.92  ? 66  TRP H CD2 1 
ATOM   19097 N NE1 . TRP G 2 48  ? -6.454  4.496   14.326 1.00 11.92  ? 66  TRP H NE1 1 
ATOM   19098 C CE2 . TRP G 2 48  ? -7.765  4.407   13.940 1.00 11.92  ? 66  TRP H CE2 1 
ATOM   19099 C CE3 . TRP G 2 48  ? -9.067  4.752   11.941 1.00 11.92  ? 66  TRP H CE3 1 
ATOM   19100 C CZ2 . TRP G 2 48  ? -8.893  4.042   14.667 1.00 11.92  ? 66  TRP H CZ2 1 
ATOM   19101 C CZ3 . TRP G 2 48  ? -10.181 4.395   12.663 1.00 11.92  ? 66  TRP H CZ3 1 
ATOM   19102 C CH2 . TRP G 2 48  ? -10.089 4.042   14.010 1.00 11.92  ? 66  TRP H CH2 1 
ATOM   19103 N N   . VAL G 2 49  ? -6.565  2.189   9.942  1.00 14.12  ? 67  VAL H N   1 
ATOM   19104 C CA  . VAL G 2 49  ? -7.565  1.143   9.738  1.00 14.12  ? 67  VAL H CA  1 
ATOM   19105 C C   . VAL G 2 49  ? -8.427  0.931   10.974 1.00 14.12  ? 67  VAL H C   1 
ATOM   19106 O O   . VAL G 2 49  ? -9.646  1.082   10.918 1.00 14.12  ? 67  VAL H O   1 
ATOM   19107 C CB  . VAL G 2 49  ? -6.912  -0.177  9.266  1.00 13.54  ? 67  VAL H CB  1 
ATOM   19108 C CG1 . VAL G 2 49  ? -6.439  -0.022  7.874  1.00 13.54  ? 67  VAL H CG1 1 
ATOM   19109 C CG2 . VAL G 2 49  ? -5.743  -0.566  10.131 1.00 13.54  ? 67  VAL H CG2 1 
ATOM   19110 N N   . SER G 2 50  ? -7.841  0.741   12.153 1.00 11.19  ? 68  SER H N   1 
ATOM   19111 C CA  . SER G 2 50  ? -8.612  0.440   13.330 1.00 11.19  ? 68  SER H CA  1 
ATOM   19112 C C   . SER G 2 50  ? -7.873  0.713   14.616 1.00 11.19  ? 68  SER H C   1 
ATOM   19113 O O   . SER G 2 50  ? -6.657  0.713   14.651 1.00 11.19  ? 68  SER H O   1 
ATOM   19114 C CB  . SER G 2 50  ? -8.997  -1.033  13.290 1.00 12.07  ? 68  SER H CB  1 
ATOM   19115 O OG  . SER G 2 50  ? -7.898  -1.822  12.905 1.00 12.07  ? 68  SER H OG  1 
ATOM   19116 N N   . GLY G 2 51  ? -8.634  0.952   15.673 1.00 10.20  ? 69  GLY H N   1 
ATOM   19117 C CA  . GLY G 2 51  ? -8.082  1.215   16.980 1.00 10.20  ? 69  GLY H CA  1 
ATOM   19118 C C   . GLY G 2 51  ? -8.917  0.515   18.015 1.00 10.20  ? 69  GLY H C   1 
ATOM   19119 O O   . GLY G 2 51  ? -10.093 0.296   17.804 1.00 10.20  ? 69  GLY H O   1 
ATOM   19120 N N   . ILE G 2 52  ? -8.311  0.161   19.135 1.00 10.43  ? 70  ILE H N   1 
ATOM   19121 C CA  . ILE G 2 52  ? -9.027  -0.520  20.195 1.00 10.43  ? 70  ILE H CA  1 
ATOM   19122 C C   . ILE G 2 52  ? -8.730  0.180   21.515 1.00 10.43  ? 70  ILE H C   1 
ATOM   19123 O O   . ILE G 2 52  ? -7.666  0.742   21.680 1.00 10.43  ? 70  ILE H O   1 
ATOM   19124 C CB  . ILE G 2 52  ? -8.650  -2.020  20.236 1.00 10.69  ? 70  ILE H CB  1 
ATOM   19125 C CG1 . ILE G 2 52  ? -9.566  -2.800  21.171 1.00 10.69  ? 70  ILE H CG1 1 
ATOM   19126 C CG2 . ILE G 2 52  ? -7.201  -2.213  20.631 1.00 10.69  ? 70  ILE H CG2 1 
ATOM   19127 C CD1 . ILE G 2 52  ? -9.208  -4.256  21.295 1.00 10.69  ? 70  ILE H CD1 1 
ATOM   19128 N N   . SER G 2 53  ? -9.688  0.183   22.435 1.00 11.20  ? 71  SER H N   1 
ATOM   19129 C CA  . SER G 2 53  ? -9.527  0.800   23.748 1.00 11.20  ? 71  SER H CA  1 
ATOM   19130 C C   . SER G 2 53  ? -8.650  -0.057  24.658 1.00 11.20  ? 71  SER H C   1 
ATOM   19131 O O   . SER G 2 53  ? -8.438  -1.231  24.388 1.00 11.20  ? 71  SER H O   1 
ATOM   19132 C CB  . SER G 2 53  ? -10.882 1.061   24.395 1.00 12.13  ? 71  SER H CB  1 
ATOM   19133 O OG  . SER G 2 53  ? -11.398 -0.107  24.987 1.00 12.13  ? 71  SER H OG  1 
ATOM   19134 N N   . GLY G 2 54  ? -8.152  0.518   25.748 1.00 13.00  ? 72  GLY H N   1 
ATOM   19135 C CA  . GLY G 2 54  ? -7.274  -0.221  26.636 1.00 13.00  ? 72  GLY H CA  1 
ATOM   19136 C C   . GLY G 2 54  ? -7.925  -1.453  27.219 1.00 13.00  ? 72  GLY H C   1 
ATOM   19137 O O   . GLY G 2 54  ? -7.308  -2.501  27.287 1.00 13.00  ? 72  GLY H O   1 
ATOM   19138 N N   . SER G 2 55  ? -9.179  -1.366  27.633 1.00 13.91  ? 73  SER H N   1 
ATOM   19139 C CA  . SER G 2 55  ? -9.835  -2.543  28.181 1.00 13.91  ? 73  SER H CA  1 
ATOM   19140 C C   . SER G 2 55  ? -10.193 -3.515  27.065 1.00 13.91  ? 73  SER H C   1 
ATOM   19141 O O   . SER G 2 55  ? -10.214 -4.723  27.266 1.00 13.91  ? 73  SER H O   1 
ATOM   19142 C CB  . SER G 2 55  ? -11.078 -2.160  28.975 1.00 16.99  ? 73  SER H CB  1 
ATOM   19143 O OG  . SER G 2 55  ? -12.115 -1.729  28.122 1.00 16.99  ? 73  SER H OG  1 
ATOM   19144 N N   . GLY G 2 56  ? -10.462 -2.980  25.882 1.00 13.28  ? 74  GLY H N   1 
ATOM   19145 C CA  . GLY G 2 56  ? -10.819 -3.792  24.736 1.00 13.28  ? 74  GLY H CA  1 
ATOM   19146 C C   . GLY G 2 56  ? -12.306 -3.757  24.465 1.00 13.28  ? 74  GLY H C   1 
ATOM   19147 O O   . GLY G 2 56  ? -12.789 -4.345  23.509 1.00 13.28  ? 74  GLY H O   1 
ATOM   19148 N N   . GLY G 2 57  ? -13.028 -3.039  25.310 1.00 17.22  ? 75  GLY H N   1 
ATOM   19149 C CA  . GLY G 2 57  ? -14.467 -2.925  25.209 1.00 17.22  ? 75  GLY H CA  1 
ATOM   19150 C C   . GLY G 2 57  ? -14.972 -2.261  23.946 1.00 17.22  ? 75  GLY H C   1 
ATOM   19151 O O   . GLY G 2 57  ? -15.978 -2.689  23.390 1.00 17.22  ? 75  GLY H O   1 
ATOM   19152 N N   . SER G 2 58  ? -14.292 -1.211  23.500 1.00 13.11  ? 76  SER H N   1 
ATOM   19153 C CA  . SER G 2 58  ? -14.700 -0.482  22.302 1.00 13.11  ? 76  SER H CA  1 
ATOM   19154 C C   . SER G 2 58  ? -13.640 -0.439  21.214 1.00 13.11  ? 76  SER H C   1 
ATOM   19155 O O   . SER G 2 58  ? -12.493 -0.131  21.475 1.00 13.11  ? 76  SER H O   1 
ATOM   19156 C CB  . SER G 2 58  ? -15.138 0.934   22.660 1.00 15.09  ? 76  SER H CB  1 
ATOM   19157 O OG  . SER G 2 58  ? -14.479 1.400   23.816 1.00 15.09  ? 76  SER H OG  1 
ATOM   19158 N N   . THR G 2 59  ? -14.047 -0.735  19.987 1.00 12.57  ? 77  THR H N   1 
ATOM   19159 C CA  . THR G 2 59  ? -13.149 -0.749  18.847 1.00 12.57  ? 77  THR H CA  1 
ATOM   19160 C C   . THR G 2 59  ? -13.728 0.079   17.711 1.00 12.57  ? 77  THR H C   1 
ATOM   19161 O O   . THR G 2 59  ? -14.938 0.184   17.576 1.00 12.57  ? 77  THR H O   1 
ATOM   19162 C CB  . THR G 2 59  ? -12.949 -2.180  18.329 1.00 12.35  ? 77  THR H CB  1 
ATOM   19163 O OG1 . THR G 2 59  ? -14.197 -2.689  17.854 1.00 12.35  ? 77  THR H OG1 1 
ATOM   19164 C CG2 . THR G 2 59  ? -12.466 -3.080  19.426 1.00 12.35  ? 77  THR H CG2 1 
ATOM   19165 N N   . ASN G 2 60  ? -12.860 0.676   16.904 1.00 12.75  ? 78  ASN H N   1 
ATOM   19166 C CA  . ASN G 2 60  ? -13.282 1.478   15.766 1.00 12.75  ? 78  ASN H CA  1 
ATOM   19167 C C   . ASN G 2 60  ? -12.595 0.951   14.527 1.00 12.75  ? 78  ASN H C   1 
ATOM   19168 O O   . ASN G 2 60  ? -11.548 0.379   14.636 1.00 12.75  ? 78  ASN H O   1 
ATOM   19169 C CB  . ASN G 2 60  ? -12.923 2.938   15.983 1.00 12.16  ? 78  ASN H CB  1 
ATOM   19170 C CG  . ASN G 2 60  ? -13.839 3.617   16.970 1.00 12.16  ? 78  ASN H CG  1 
ATOM   19171 O OD1 . ASN G 2 60  ? -14.924 4.065   16.618 1.00 12.16  ? 78  ASN H OD1 1 
ATOM   19172 N ND2 . ASN G 2 60  ? -13.405 3.699   18.213 1.00 12.16  ? 78  ASN H ND2 1 
ATOM   19173 N N   . TYR G 2 61  ? -13.203 1.124   13.361 1.00 16.72  ? 79  TYR H N   1 
ATOM   19174 C CA  . TYR G 2 61  ? -12.615 0.662   12.113 1.00 16.72  ? 79  TYR H CA  1 
ATOM   19175 C C   . TYR G 2 61  ? -12.875 1.648   11.006 1.00 16.72  ? 79  TYR H C   1 
ATOM   19176 O O   . TYR G 2 61  ? -13.887 2.327   11.005 1.00 16.72  ? 79  TYR H O   1 
ATOM   19177 C CB  . TYR G 2 61  ? -13.241 -0.650  11.654 1.00 14.52  ? 79  TYR H CB  1 
ATOM   19178 C CG  . TYR G 2 61  ? -13.142 -1.797  12.609 1.00 14.52  ? 79  TYR H CG  1 
ATOM   19179 C CD1 . TYR G 2 61  ? -12.109 -2.708  12.524 1.00 14.52  ? 79  TYR H CD1 1 
ATOM   19180 C CD2 . TYR G 2 61  ? -14.100 -1.983  13.581 1.00 14.52  ? 79  TYR H CD2 1 
ATOM   19181 C CE1 . TYR G 2 61  ? -12.026 -3.764  13.399 1.00 14.52  ? 79  TYR H CE1 1 
ATOM   19182 C CE2 . TYR G 2 61  ? -14.026 -3.032  14.458 1.00 14.52  ? 79  TYR H CE2 1 
ATOM   19183 C CZ  . TYR G 2 61  ? -12.988 -3.918  14.361 1.00 14.52  ? 79  TYR H CZ  1 
ATOM   19184 O OH  . TYR G 2 61  ? -12.925 -4.965  15.240 1.00 14.52  ? 79  TYR H OH  1 
ATOM   19185 N N   . ALA G 2 62  ? -11.965 1.709   10.043 1.00 21.36  ? 80  ALA H N   1 
ATOM   19186 C CA  . ALA G 2 62  ? -12.138 2.565   8.883  1.00 21.36  ? 80  ALA H CA  1 
ATOM   19187 C C   . ALA G 2 62  ? -13.200 1.925   8.000  1.00 21.36  ? 80  ALA H C   1 
ATOM   19188 O O   . ALA G 2 62  ? -13.336 0.709   7.970  1.00 21.36  ? 80  ALA H O   1 
ATOM   19189 C CB  . ALA G 2 62  ? -10.835 2.714   8.131  1.00 18.30  ? 80  ALA H CB  1 
ATOM   19190 N N   . GLU G 2 63  ? -13.920 2.723   7.228  1.00 26.01  ? 81  GLU H N   1 
ATOM   19191 C CA  . GLU G 2 63  ? -14.984 2.168   6.400  1.00 26.01  ? 81  GLU H CA  1 
ATOM   19192 C C   . GLU G 2 63  ? -14.505 1.146   5.384  1.00 26.01  ? 81  GLU H C   1 
ATOM   19193 O O   . GLU G 2 63  ? -15.181 0.157   5.138  1.00 26.01  ? 81  GLU H O   1 
ATOM   19194 C CB  . GLU G 2 63  ? -15.774 3.274   5.707  1.00 33.05  ? 81  GLU H CB  1 
ATOM   19195 C CG  . GLU G 2 63  ? -17.038 3.670   6.449  1.00 33.05  ? 81  GLU H CG  1 
ATOM   19196 C CD  . GLU G 2 63  ? -18.058 2.548   6.495  1.00 33.05  ? 81  GLU H CD  1 
ATOM   19197 O OE1 . GLU G 2 63  ? -18.048 1.697   5.582  1.00 33.05  ? 81  GLU H OE1 1 
ATOM   19198 O OE2 . GLU G 2 63  ? -18.872 2.519   7.440  1.00 33.05  ? 81  GLU H OE2 1 
ATOM   19199 N N   . SER G 2 64  ? -13.344 1.376   4.791  1.00 24.93  ? 82  SER H N   1 
ATOM   19200 C CA  . SER G 2 64  ? -12.822 0.458   3.793  1.00 24.93  ? 82  SER H CA  1 
ATOM   19201 C C   . SER G 2 64  ? -12.569 -0.934  4.351  1.00 24.93  ? 82  SER H C   1 
ATOM   19202 O O   . SER G 2 64  ? -12.829 -1.927  3.684  1.00 24.93  ? 82  SER H O   1 
ATOM   19203 C CB  . SER G 2 64  ? -11.535 1.008   3.191  1.00 26.61  ? 82  SER H CB  1 
ATOM   19204 O OG  . SER G 2 64  ? -10.611 1.337   4.206  1.00 26.61  ? 82  SER H OG  1 
ATOM   19205 N N   . VAL G 2 65  ? -12.048 -1.007  5.566  1.00 22.79  ? 83  VAL H N   1 
ATOM   19206 C CA  . VAL G 2 65  ? -11.748 -2.290  6.188  1.00 22.79  ? 83  VAL H CA  1 
ATOM   19207 C C   . VAL G 2 65  ? -12.842 -2.852  7.087  1.00 22.79  ? 83  VAL H C   1 
ATOM   19208 O O   . VAL G 2 65  ? -12.682 -3.928  7.637  1.00 22.79  ? 83  VAL H O   1 
ATOM   19209 C CB  . VAL G 2 65  ? -10.477 -2.194  7.041  1.00 21.26  ? 83  VAL H CB  1 
ATOM   19210 C CG1 . VAL G 2 65  ? -9.447  -1.319  6.351  1.00 21.26  ? 83  VAL H CG1 1 
ATOM   19211 C CG2 . VAL G 2 65  ? -10.813 -1.624  8.405  1.00 21.26  ? 83  VAL H CG2 1 
ATOM   19212 N N   . ARG G 2 66  ? -13.950 -2.143  7.242  1.00 23.23  ? 84  ARG H N   1 
ATOM   19213 C CA  . ARG G 2 66  ? -14.994 -2.606  8.149  1.00 23.23  ? 84  ARG H CA  1 
ATOM   19214 C C   . ARG G 2 66  ? -15.724 -3.873  7.740  1.00 23.23  ? 84  ARG H C   1 
ATOM   19215 O O   . ARG G 2 66  ? -16.190 -4.008  6.616  1.00 23.23  ? 84  ARG H O   1 
ATOM   19216 C CB  . ARG G 2 66  ? -16.017 -1.501  8.381  1.00 24.21  ? 84  ARG H CB  1 
ATOM   19217 C CG  . ARG G 2 66  ? -16.887 -1.719  9.603  1.00 24.21  ? 84  ARG H CG  1 
ATOM   19218 C CD  . ARG G 2 66  ? -17.946 -0.640  9.720  1.00 24.21  ? 84  ARG H CD  1 
ATOM   19219 N NE  . ARG G 2 66  ? -17.429 0.683   9.383  1.00 24.21  ? 84  ARG H NE  1 
ATOM   19220 C CZ  . ARG G 2 66  ? -16.917 1.533   10.264 1.00 24.21  ? 84  ARG H CZ  1 
ATOM   19221 N NH1 . ARG G 2 66  ? -16.476 2.713   9.861  1.00 24.21  ? 84  ARG H NH1 1 
ATOM   19222 N NH2 . ARG G 2 66  ? -16.848 1.207   11.545 1.00 24.21  ? 84  ARG H NH2 1 
ATOM   19223 N N   . GLY G 2 67  ? -15.830 -4.789  8.692  1.00 26.24  ? 85  GLY H N   1 
ATOM   19224 C CA  . GLY G 2 67  ? -16.522 -6.054  8.529  1.00 26.24  ? 85  GLY H CA  1 
ATOM   19225 C C   . GLY G 2 67  ? -15.662 -7.193  8.026  1.00 26.24  ? 85  GLY H C   1 
ATOM   19226 O O   . GLY G 2 67  ? -16.031 -8.351  8.156  1.00 26.24  ? 85  GLY H O   1 
ATOM   19227 N N   . ARG G 2 68  ? -14.500 -6.870  7.476  1.00 27.61  ? 86  ARG H N   1 
ATOM   19228 C CA  . ARG G 2 68  ? -13.590 -7.888  6.993  1.00 27.61  ? 86  ARG H CA  1 
ATOM   19229 C C   . ARG G 2 68  ? -12.500 -8.062  8.025  1.00 27.61  ? 86  ARG H C   1 
ATOM   19230 O O   . ARG G 2 68  ? -12.011 -9.163  8.256  1.00 27.61  ? 86  ARG H O   1 
ATOM   19231 C CB  . ARG G 2 68  ? -12.972 -7.477  5.662  1.00 30.95  ? 86  ARG H CB  1 
ATOM   19232 C CG  . ARG G 2 68  ? -13.850 -6.586  4.811  1.00 30.95  ? 86  ARG H CG  1 
ATOM   19233 C CD  . ARG G 2 68  ? -13.345 -6.544  3.383  1.00 30.95  ? 86  ARG H CD  1 
ATOM   19234 N NE  . ARG G 2 68  ? -11.889 -6.548  3.302  1.00 30.95  ? 86  ARG H NE  1 
ATOM   19235 C CZ  . ARG G 2 68  ? -11.155 -5.485  2.999  1.00 30.95  ? 86  ARG H CZ  1 
ATOM   19236 N NH1 . ARG G 2 68  ? -9.839  -5.579  2.940  1.00 30.95  ? 86  ARG H NH1 1 
ATOM   19237 N NH2 . ARG G 2 68  ? -11.739 -4.327  2.750  1.00 30.95  ? 86  ARG H NH2 1 
ATOM   19238 N N   . PHE G 2 69  ? -12.141 -6.953  8.658  1.00 24.16  ? 87  PHE H N   1 
ATOM   19239 C CA  . PHE G 2 69  ? -11.108 -6.934  9.674  1.00 24.16  ? 87  PHE H CA  1 
ATOM   19240 C C   . PHE G 2 69  ? -11.722 -6.882  11.053 1.00 24.16  ? 87  PHE H C   1 
ATOM   19241 O O   . PHE G 2 69  ? -12.810 -6.353  11.240 1.00 24.16  ? 87  PHE H O   1 
ATOM   19242 C CB  . PHE G 2 69  ? -10.257 -5.671  9.533  1.00 26.91  ? 87  PHE H CB  1 
ATOM   19243 C CG  . PHE G 2 69  ? -9.305  -5.687  8.377  1.00 26.91  ? 87  PHE H CG  1 
ATOM   19244 C CD1 . PHE G 2 69  ? -8.222  -4.829  8.359  1.00 26.91  ? 87  PHE H CD1 1 
ATOM   19245 C CD2 . PHE G 2 69  ? -9.483  -6.547  7.318  1.00 26.91  ? 87  PHE H CD2 1 
ATOM   19246 C CE1 . PHE G 2 69  ? -7.341  -4.823  7.301  1.00 26.91  ? 87  PHE H CE1 1 
ATOM   19247 C CE2 . PHE G 2 69  ? -8.602  -6.552  6.259  1.00 26.91  ? 87  PHE H CE2 1 
ATOM   19248 C CZ  . PHE G 2 69  ? -7.530  -5.689  6.250  1.00 26.91  ? 87  PHE H CZ  1 
ATOM   19249 N N   . THR G 2 70  ? -10.989 -7.401  12.027 1.00 19.19  ? 88  THR H N   1 
ATOM   19250 C CA  . THR G 2 70  ? -11.411 -7.372  13.415 1.00 19.19  ? 88  THR H CA  1 
ATOM   19251 C C   . THR G 2 70  ? -10.176 -7.231  14.287 1.00 19.19  ? 88  THR H C   1 
ATOM   19252 O O   . THR G 2 70  ? -9.232  -7.994  14.167 1.00 19.19  ? 88  THR H O   1 
ATOM   19253 C CB  . THR G 2 70  ? -12.230 -8.605  13.809 1.00 23.13  ? 88  THR H CB  1 
ATOM   19254 O OG1 . THR G 2 70  ? -12.115 -8.817  15.219 1.00 23.13  ? 88  THR H OG1 1 
ATOM   19255 C CG2 . THR G 2 70  ? -11.737 -9.830  13.081 1.00 23.13  ? 88  THR H CG2 1 
ATOM   19256 N N   . ILE G 2 71  ? -10.198 -6.248  15.173 1.00 16.82  ? 89  ILE H N   1 
ATOM   19257 C CA  . ILE G 2 71  ? -9.072  -5.963  16.045 1.00 16.82  ? 89  ILE H CA  1 
ATOM   19258 C C   . ILE G 2 71  ? -9.359  -6.400  17.469 1.00 16.82  ? 89  ILE H C   1 
ATOM   19259 O O   . ILE G 2 71  ? -10.430 -6.157  17.995 1.00 16.82  ? 89  ILE H O   1 
ATOM   19260 C CB  . ILE G 2 71  ? -8.742  -4.458  16.027 1.00 13.31  ? 89  ILE H CB  1 
ATOM   19261 C CG1 . ILE G 2 71  ? -7.421  -4.176  16.737 1.00 13.31  ? 89  ILE H CG1 1 
ATOM   19262 C CG2 . ILE G 2 71  ? -9.863  -3.662  16.662 1.00 13.31  ? 89  ILE H CG2 1 
ATOM   19263 C CD1 . ILE G 2 71  ? -6.999  -2.729  16.683 1.00 13.31  ? 89  ILE H CD1 1 
ATOM   19264 N N   . SER G 2 72  ? -8.407  -7.091  18.075 1.00 17.88  ? 90  SER H N   1 
ATOM   19265 C CA  . SER G 2 72  ? -8.552  -7.558  19.441 1.00 17.88  ? 90  SER H CA  1 
ATOM   19266 C C   . SER G 2 72  ? -7.221  -7.468  20.155 1.00 17.88  ? 90  SER H C   1 
ATOM   19267 O O   . SER G 2 72  ? -6.190  -7.390  19.519 1.00 17.88  ? 90  SER H O   1 
ATOM   19268 C CB  . SER G 2 72  ? -9.062  -8.995  19.454 1.00 23.09  ? 90  SER H CB  1 
ATOM   19269 O OG  . SER G 2 72  ? -8.356  -9.797  18.524 1.00 23.09  ? 90  SER H OG  1 
ATOM   19270 N N   . ARG G 2 73  ? -7.240  -7.435  21.475 1.00 18.95  ? 91  ARG H N   1 
ATOM   19271 C CA  . ARG G 2 73  ? -6.002  -7.387  22.228 1.00 18.95  ? 91  ARG H CA  1 
ATOM   19272 C C   . ARG G 2 73  ? -6.057  -8.328  23.411 1.00 18.95  ? 91  ARG H C   1 
ATOM   19273 O O   . ARG G 2 73  ? -7.114  -8.532  23.990 1.00 18.95  ? 91  ARG H O   1 
ATOM   19274 C CB  . ARG G 2 73  ? -5.766  -5.984  22.753 1.00 13.36  ? 91  ARG H CB  1 
ATOM   19275 C CG  . ARG G 2 73  ? -6.921  -5.466  23.583 1.00 13.36  ? 91  ARG H CG  1 
ATOM   19276 C CD  . ARG G 2 73  ? -6.461  -4.448  24.598 1.00 13.36  ? 91  ARG H CD  1 
ATOM   19277 N NE  . ARG G 2 73  ? -5.881  -3.264  23.985 1.00 13.36  ? 91  ARG H NE  1 
ATOM   19278 C CZ  . ARG G 2 73  ? -4.980  -2.497  24.577 1.00 13.36  ? 91  ARG H CZ  1 
ATOM   19279 N NH1 . ARG G 2 73  ? -4.547  -2.795  25.783 1.00 13.36  ? 91  ARG H NH1 1 
ATOM   19280 N NH2 . ARG G 2 73  ? -4.503  -1.441  23.957 1.00 13.36  ? 91  ARG H NH2 1 
ATOM   19281 N N   . ASP G 2 74  ? -4.928  -8.919  23.767 1.00 21.55  ? 92  ASP H N   1 
ATOM   19282 C CA  . ASP G 2 74  ? -4.899  -9.764  24.944 1.00 21.55  ? 92  ASP H CA  1 
ATOM   19283 C C   . ASP G 2 74  ? -4.053  -9.009  25.951 1.00 21.55  ? 92  ASP H C   1 
ATOM   19284 O O   . ASP G 2 74  ? -2.849  -8.899  25.797 1.00 21.55  ? 92  ASP H O   1 
ATOM   19285 C CB  . ASP G 2 74  ? -4.278  -11.119 24.629 1.00 28.19  ? 92  ASP H CB  1 
ATOM   19286 C CG  . ASP G 2 74  ? -4.505  -12.129 25.731 1.00 28.19  ? 92  ASP H CG  1 
ATOM   19287 O OD1 . ASP G 2 74  ? -4.821  -11.714 26.860 1.00 28.19  ? 92  ASP H OD1 1 
ATOM   19288 O OD2 . ASP G 2 74  ? -4.368  -13.341 25.473 1.00 28.19  ? 92  ASP H OD2 1 
ATOM   19289 N N   . ASN G 2 75  ? -4.692  -8.428  26.955 1.00 20.95  ? 93  ASN H N   1 
ATOM   19290 C CA  . ASN G 2 75  ? -3.961  -7.643  27.934 1.00 20.95  ? 93  ASN H CA  1 
ATOM   19291 C C   . ASN G 2 75  ? -3.021  -8.477  28.780 1.00 20.95  ? 93  ASN H C   1 
ATOM   19292 O O   . ASN G 2 75  ? -1.965  -8.006  29.180 1.00 20.95  ? 93  ASN H O   1 
ATOM   19293 C CB  . ASN G 2 75  ? -4.917  -6.844  28.810 1.00 17.68  ? 93  ASN H CB  1 
ATOM   19294 C CG  . ASN G 2 75  ? -5.594  -5.725  28.055 1.00 17.68  ? 93  ASN H CG  1 
ATOM   19295 O OD1 . ASN G 2 75  ? -5.240  -5.428  26.925 1.00 17.68  ? 93  ASN H OD1 1 
ATOM   19296 N ND2 . ASN G 2 75  ? -6.574  -5.102  28.679 1.00 17.68  ? 93  ASN H ND2 1 
ATOM   19297 N N   . SER G 2 76  ? -3.406  -9.712  29.065 1.00 22.77  ? 94  SER H N   1 
ATOM   19298 C CA  . SER G 2 76  ? -2.562  -10.596 29.856 1.00 22.77  ? 94  SER H CA  1 
ATOM   19299 C C   . SER G 2 76  ? -1.248  -10.896 29.145 1.00 22.77  ? 94  SER H C   1 
ATOM   19300 O O   . SER G 2 76  ? -0.204  -10.982 29.778 1.00 22.77  ? 94  SER H O   1 
ATOM   19301 C CB  . SER G 2 76  ? -3.298  -11.882 30.233 1.00 26.27  ? 94  SER H CB  1 
ATOM   19302 O OG  . SER G 2 76  ? -4.327  -12.173 29.311 1.00 26.27  ? 94  SER H OG  1 
ATOM   19303 N N   . LYS G 2 77  ? -1.310  -11.071 27.831 1.00 23.72  ? 95  LYS H N   1 
ATOM   19304 C CA  . LYS G 2 77  ? -0.125  -11.357 27.032 1.00 23.72  ? 95  LYS H CA  1 
ATOM   19305 C C   . LYS G 2 77  ? 0.510   -10.141 26.363 1.00 23.72  ? 95  LYS H C   1 
ATOM   19306 O O   . LYS G 2 77  ? 1.426   -10.307 25.567 1.00 23.72  ? 95  LYS H O   1 
ATOM   19307 C CB  . LYS G 2 77  ? -0.443  -12.405 25.969 1.00 27.02  ? 95  LYS H CB  1 
ATOM   19308 C CG  . LYS G 2 77  ? -0.877  -13.747 26.525 1.00 27.02  ? 95  LYS H CG  1 
ATOM   19309 C CD  . LYS G 2 77  ? -1.134  -14.736 25.402 1.00 27.02  ? 95  LYS H CD  1 
ATOM   19310 C CE  . LYS G 2 77  ? -1.390  -16.134 25.941 1.00 27.02  ? 95  LYS H CE  1 
ATOM   19311 N NZ  . LYS G 2 77  ? -0.229  -16.647 26.721 1.00 27.02  ? 95  LYS H NZ  1 
ATOM   19312 N N   . ASN G 2 78  ? -0.013  -8.944  26.636 1.00 20.03  ? 96  ASN H N   1 
ATOM   19313 C CA  . ASN G 2 78  ? 0.485   -7.682  26.065 1.00 20.03  ? 96  ASN H CA  1 
ATOM   19314 C C   . ASN G 2 78  ? 0.527   -7.708  24.547 1.00 20.03  ? 96  ASN H C   1 
ATOM   19315 O O   . ASN G 2 78  ? 1.474   -7.223  23.955 1.00 20.03  ? 96  ASN H O   1 
ATOM   19316 C CB  . ASN G 2 78  ? 1.868   -7.305  26.607 1.00 18.39  ? 96  ASN H CB  1 
ATOM   19317 C CG  . ASN G 2 78  ? 1.817   -6.745  28.005 1.00 18.39  ? 96  ASN H CG  1 
ATOM   19318 O OD1 . ASN G 2 78  ? 0.895   -7.021  28.762 1.00 18.39  ? 96  ASN H OD1 1 
ATOM   19319 N ND2 . ASN G 2 78  ? 2.816   -5.952  28.357 1.00 18.39  ? 96  ASN H ND2 1 
ATOM   19320 N N   . THR G 2 79  ? -0.500  -8.259  23.918 1.00 20.98  ? 97  THR H N   1 
ATOM   19321 C CA  . THR G 2 79  ? -0.521  -8.376  22.468 1.00 20.98  ? 97  THR H CA  1 
ATOM   19322 C C   . THR G 2 79  ? -1.709  -7.712  21.791 1.00 20.98  ? 97  THR H C   1 
ATOM   19323 O O   . THR G 2 79  ? -2.832  -7.804  22.258 1.00 20.98  ? 97  THR H O   1 
ATOM   19324 C CB  . THR G 2 79  ? -0.499  -9.858  22.044 1.00 24.55  ? 97  THR H CB  1 
ATOM   19325 O OG1 . THR G 2 79  ? 0.453   -10.564 22.838 1.00 24.55  ? 97  THR H OG1 1 
ATOM   19326 C CG2 . THR G 2 79  ? -0.113  -10.000 20.596 1.00 24.55  ? 97  THR H CG2 1 
ATOM   19327 N N   . LEU G 2 80  ? -1.446  -7.048  20.672 1.00 19.88  ? 98  LEU H N   1 
ATOM   19328 C CA  . LEU G 2 80  ? -2.472  -6.422  19.866 1.00 19.88  ? 98  LEU H CA  1 
ATOM   19329 C C   . LEU G 2 80  ? -2.623  -7.333  18.662 1.00 19.88  ? 98  LEU H C   1 
ATOM   19330 O O   . LEU G 2 80  ? -1.655  -7.604  17.982 1.00 19.88  ? 98  LEU H O   1 
ATOM   19331 C CB  . LEU G 2 80  ? -2.015  -5.043  19.421 1.00 15.57  ? 98  LEU H CB  1 
ATOM   19332 C CG  . LEU G 2 80  ? -3.005  -4.251  18.580 1.00 15.57  ? 98  LEU H CG  1 
ATOM   19333 C CD1 . LEU G 2 80  ? -4.300  -4.071  19.349 1.00 15.57  ? 98  LEU H CD1 1 
ATOM   19334 C CD2 . LEU G 2 80  ? -2.414  -2.910  18.189 1.00 15.57  ? 98  LEU H CD2 1 
ATOM   19335 N N   . TYR G 2 81  ? -3.832  -7.808  18.397 1.00 20.48  ? 99  TYR H N   1 
ATOM   19336 C CA  . TYR G 2 81  ? -4.075  -8.724  17.287 1.00 20.48  ? 99  TYR H CA  1 
ATOM   19337 C C   . TYR G 2 81  ? -4.972  -8.136  16.230 1.00 20.48  ? 99  TYR H C   1 
ATOM   19338 O O   . TYR G 2 81  ? -5.980  -7.534  16.548 1.00 20.48  ? 99  TYR H O   1 
ATOM   19339 C CB  . TYR G 2 81  ? -4.794  -9.975  17.782 1.00 25.65  ? 99  TYR H CB  1 
ATOM   19340 C CG  . TYR G 2 81  ? -3.972  -10.947 18.577 1.00 25.65  ? 99  TYR H CG  1 
ATOM   19341 C CD1 . TYR G 2 81  ? -3.047  -11.765 17.960 1.00 25.65  ? 99  TYR H CD1 1 
ATOM   19342 C CD2 . TYR G 2 81  ? -4.156  -11.077 19.941 1.00 25.65  ? 99  TYR H CD2 1 
ATOM   19343 C CE1 . TYR G 2 81  ? -2.302  -12.667 18.683 1.00 25.65  ? 99  TYR H CE1 1 
ATOM   19344 C CE2 . TYR G 2 81  ? -3.419  -11.978 20.674 1.00 25.65  ? 99  TYR H CE2 1 
ATOM   19345 C CZ  . TYR G 2 81  ? -2.492  -12.772 20.039 1.00 25.65  ? 99  TYR H CZ  1 
ATOM   19346 O OH  . TYR G 2 81  ? -1.750  -13.677 20.761 1.00 25.65  ? 99  TYR H OH  1 
ATOM   19347 N N   . LEU G 2 82  ? -4.628  -8.334  14.968 1.00 22.08  ? 100 LEU H N   1 
ATOM   19348 C CA  . LEU G 2 82  ? -5.463  -7.848  13.884 1.00 22.08  ? 100 LEU H CA  1 
ATOM   19349 C C   . LEU G 2 82  ? -5.753  -9.000  12.958 1.00 22.08  ? 100 LEU H C   1 
ATOM   19350 O O   . LEU G 2 82  ? -4.867  -9.492  12.282 1.00 22.08  ? 100 LEU H O   1 
ATOM   19351 C CB  . LEU G 2 82  ? -4.790  -6.730  13.100 1.00 18.14  ? 100 LEU H CB  1 
ATOM   19352 C CG  . LEU G 2 82  ? -5.534  -6.305  11.834 1.00 18.14  ? 100 LEU H CG  1 
ATOM   19353 C CD1 . LEU G 2 82  ? -6.822  -5.579  12.160 1.00 18.14  ? 100 LEU H CD1 1 
ATOM   19354 C CD2 . LEU G 2 82  ? -4.658  -5.433  10.959 1.00 18.14  ? 100 LEU H CD2 1 
ATOM   19355 N N   . GLU G 2 83  ? -7.006  -9.420  12.917 1.00 26.11  ? 101 GLU H N   1 
ATOM   19356 C CA  . GLU G 2 83  ? -7.396  -10.524 12.068 1.00 26.11  ? 101 GLU H CA  1 
ATOM   19357 C C   . GLU G 2 83  ? -8.065  -9.976  10.829 1.00 26.11  ? 101 GLU H C   1 
ATOM   19358 O O   . GLU G 2 83  ? -9.037  -9.242  10.917 1.00 26.11  ? 101 GLU H O   1 
ATOM   19359 C CB  . GLU G 2 83  ? -8.340  -11.444 12.828 1.00 37.72  ? 101 GLU H CB  1 
ATOM   19360 C CG  . GLU G 2 83  ? -9.397  -12.101 11.971 1.00 37.72  ? 101 GLU H CG  1 
ATOM   19361 C CD  . GLU G 2 83  ? -10.358 -12.922 12.798 1.00 37.72  ? 101 GLU H CD  1 
ATOM   19362 O OE1 . GLU G 2 83  ? -9.917  -13.503 13.811 1.00 37.72  ? 101 GLU H OE1 1 
ATOM   19363 O OE2 . GLU G 2 83  ? -11.551 -12.980 12.439 1.00 37.72  ? 101 GLU H OE2 1 
ATOM   19364 N N   . MET G 2 84  ? -7.544  -10.351 9.669  1.00 27.03  ? 102 MET H N   1 
ATOM   19365 C CA  . MET G 2 84  ? -8.065  -9.864  8.406  1.00 27.03  ? 102 MET H CA  1 
ATOM   19366 C C   . MET G 2 84  ? -8.709  -10.984 7.606  1.00 27.03  ? 102 MET H C   1 
ATOM   19367 O O   . MET G 2 84  ? -8.100  -12.019 7.378  1.00 27.03  ? 102 MET H O   1 
ATOM   19368 C CB  . MET G 2 84  ? -6.927  -9.229  7.612  1.00 27.82  ? 102 MET H CB  1 
ATOM   19369 C CG  . MET G 2 84  ? -5.774  -8.783  8.496  1.00 27.82  ? 102 MET H CG  1 
ATOM   19370 S SD  . MET G 2 84  ? -4.509  -7.762  7.721  1.00 27.82  ? 102 MET H SD  1 
ATOM   19371 C CE  . MET G 2 84  ? -4.319  -8.538  6.125  1.00 27.82  ? 102 MET H CE  1 
ATOM   19372 N N   . ASN G 2 85  ? -9.946  -10.770 7.182  1.00 29.82  ? 103 ASN H N   1 
ATOM   19373 C CA  . ASN G 2 85  ? -10.676 -11.764 6.415  1.00 29.82  ? 103 ASN H CA  1 
ATOM   19374 C C   . ASN G 2 85  ? -11.051 -11.187 5.066  1.00 29.82  ? 103 ASN H C   1 
ATOM   19375 O O   . ASN G 2 85  ? -11.097 -9.973  4.910  1.00 29.82  ? 103 ASN H O   1 
ATOM   19376 C CB  . ASN G 2 85  ? -11.946 -12.177 7.157  1.00 30.66  ? 103 ASN H CB  1 
ATOM   19377 C CG  . ASN G 2 85  ? -11.656 -12.966 8.415  1.00 30.66  ? 103 ASN H CG  1 
ATOM   19378 O OD1 . ASN G 2 85  ? -10.989 -13.995 8.375  1.00 30.66  ? 103 ASN H OD1 1 
ATOM   19379 N ND2 . ASN G 2 85  ? -12.165 -12.490 9.540  1.00 30.66  ? 103 ASN H ND2 1 
ATOM   19380 N N   . SER G 2 86  ? -11.323 -12.062 4.102  1.00 32.64  ? 104 SER H N   1 
ATOM   19381 C CA  . SER G 2 86  ? -11.689 -11.665 2.743  1.00 32.64  ? 104 SER H CA  1 
ATOM   19382 C C   . SER G 2 86  ? -10.707 -10.646 2.188  1.00 32.64  ? 104 SER H C   1 
ATOM   19383 O O   . SER G 2 86  ? -11.103 -9.604  1.688  1.00 32.64  ? 104 SER H O   1 
ATOM   19384 C CB  . SER G 2 86  ? -13.116 -11.111 2.688  1.00 31.66  ? 104 SER H CB  1 
ATOM   19385 O OG  . SER G 2 86  ? -13.955 -11.769 3.617  1.00 31.66  ? 104 SER H OG  1 
ATOM   19386 N N   . LEU G 2 87  ? -9.419  -10.961 2.268  1.00 37.51  ? 105 LEU H N   1 
ATOM   19387 C CA  . LEU G 2 87  ? -8.376  -10.068 1.777  1.00 37.51  ? 105 LEU H CA  1 
ATOM   19388 C C   . LEU G 2 87  ? -8.437  -9.853  0.271  1.00 37.51  ? 105 LEU H C   1 
ATOM   19389 O O   . LEU G 2 87  ? -8.913  -10.700 -0.476 1.00 37.51  ? 105 LEU H O   1 
ATOM   19390 C CB  . LEU G 2 87  ? -6.996  -10.588 2.167  1.00 33.58  ? 105 LEU H CB  1 
ATOM   19391 C CG  . LEU G 2 87  ? -6.564  -10.387 3.617  1.00 33.58  ? 105 LEU H CG  1 
ATOM   19392 C CD1 . LEU G 2 87  ? -5.396  -11.295 3.952  1.00 33.58  ? 105 LEU H CD1 1 
ATOM   19393 C CD2 . LEU G 2 87  ? -6.196  -8.939  3.867  1.00 33.58  ? 105 LEU H CD2 1 
ATOM   19394 N N   . ARG G 2 88  ? -7.920  -8.718  -0.171 1.00 38.87  ? 106 ARG H N   1 
ATOM   19395 C CA  . ARG G 2 88  ? -7.921  -8.367  -1.581 1.00 38.87  ? 106 ARG H CA  1 
ATOM   19396 C C   . ARG G 2 88  ? -6.622  -7.686  -1.972 1.00 38.87  ? 106 ARG H C   1 
ATOM   19397 O O   . ARG G 2 88  ? -5.810  -7.357  -1.120 1.00 38.87  ? 106 ARG H O   1 
ATOM   19398 C CB  . ARG G 2 88  ? -9.125  -7.502  -1.928 1.00 42.61  ? 106 ARG H CB  1 
ATOM   19399 C CG  . ARG G 2 88  ? -9.418  -6.424  -0.914 1.00 42.61  ? 106 ARG H CG  1 
ATOM   19400 C CD  . ARG G 2 88  ? -10.865 -5.991  -1.010 1.00 42.61  ? 106 ARG H CD  1 
ATOM   19401 N NE  . ARG G 2 88  ? -11.771 -7.091  -0.720 1.00 42.61  ? 106 ARG H NE  1 
ATOM   19402 C CZ  . ARG G 2 88  ? -13.027 -6.932  -0.326 1.00 42.61  ? 106 ARG H CZ  1 
ATOM   19403 N NH1 . ARG G 2 88  ? -13.522 -5.712  -0.174 1.00 42.61  ? 106 ARG H NH1 1 
ATOM   19404 N NH2 . ARG G 2 88  ? -13.785 -7.991  -0.079 1.00 42.61  ? 106 ARG H NH2 1 
ATOM   19405 N N   . VAL G 2 89  ? -6.412  -7.486  -3.266 1.00 41.01  ? 107 VAL H N   1 
ATOM   19406 C CA  . VAL G 2 89  ? -5.178  -6.865  -3.732 1.00 41.01  ? 107 VAL H CA  1 
ATOM   19407 C C   . VAL G 2 89  ? -4.996  -5.455  -3.193 1.00 41.01  ? 107 VAL H C   1 
ATOM   19408 O O   . VAL G 2 89  ? -3.879  -5.001  -3.002 1.00 41.01  ? 107 VAL H O   1 
ATOM   19409 C CB  . VAL G 2 89  ? -5.084  -6.859  -5.264 1.00 41.67  ? 107 VAL H CB  1 
ATOM   19410 C CG1 . VAL G 2 89  ? -3.909  -6.010  -5.713 1.00 41.67  ? 107 VAL H CG1 1 
ATOM   19411 C CG2 . VAL G 2 89  ? -4.943  -8.278  -5.781 1.00 41.67  ? 107 VAL H CG2 1 
ATOM   19412 N N   . GLU G 2 90  ? -6.104  -4.776  -2.925 1.00 38.62  ? 108 GLU H N   1 
ATOM   19413 C CA  . GLU G 2 90  ? -6.094  -3.412  -2.399 1.00 38.62  ? 108 GLU H CA  1 
ATOM   19414 C C   . GLU G 2 90  ? -5.448  -3.337  -1.024 1.00 38.62  ? 108 GLU H C   1 
ATOM   19415 O O   . GLU G 2 90  ? -4.773  -2.367  -0.693 1.00 38.62  ? 108 GLU H O   1 
ATOM   19416 C CB  . GLU G 2 90  ? -7.518  -2.876  -2.301 1.00 48.99  ? 108 GLU H CB  1 
ATOM   19417 C CG  . GLU G 2 90  ? -8.449  -3.395  -3.381 1.00 48.99  ? 108 GLU H CG  1 
ATOM   19418 C CD  . GLU G 2 90  ? -9.899  -3.344  -2.955 1.00 48.99  ? 108 GLU H CD  1 
ATOM   19419 O OE1 . GLU G 2 90  ? -10.774 -3.695  -3.773 1.00 48.99  ? 108 GLU H OE1 1 
ATOM   19420 O OE2 . GLU G 2 90  ? -10.160 -2.952  -1.800 1.00 48.99  ? 108 GLU H OE2 1 
ATOM   19421 N N   . ASP G 2 91  ? -5.440  -4.457  -0.318 1.00 32.86  ? 109 ASP H N   1 
ATOM   19422 C CA  . ASP G 2 91  ? -4.817  -4.513  0.999  1.00 32.86  ? 109 ASP H CA  1 
ATOM   19423 C C   . ASP G 2 91  ? -3.306  -4.602  1.049  1.00 32.86  ? 109 ASP H C   1 
ATOM   19424 O O   . ASP G 2 91  ? -2.752  -4.612  2.140  1.00 32.86  ? 109 ASP H O   1 
ATOM   19425 C CB  . ASP G 2 91  ? -5.323  -5.715  1.757  1.00 36.19  ? 109 ASP H CB  1 
ATOM   19426 C CG  . ASP G 2 91  ? -6.776  -5.671  1.955  1.00 36.19  ? 109 ASP H CG  1 
ATOM   19427 O OD1 . ASP G 2 91  ? -7.362  -4.578  1.845  1.00 36.19  ? 109 ASP H OD1 1 
ATOM   19428 O OD2 . ASP G 2 91  ? -7.371  -6.726  2.233  1.00 36.19  ? 109 ASP H OD2 1 
ATOM   19429 N N   . THR G 2 92  ? -2.617  -4.681  -0.082 1.00 31.87  ? 110 THR H N   1 
ATOM   19430 C CA  . THR G 2 92  ? -1.172  -4.790  0.024  1.00 31.87  ? 110 THR H CA  1 
ATOM   19431 C C   . THR G 2 92  ? -0.679  -3.474  0.575  1.00 31.87  ? 110 THR H C   1 
ATOM   19432 O O   . THR G 2 92  ? -0.889  -2.430  -0.027 1.00 31.87  ? 110 THR H O   1 
ATOM   19433 C CB  . THR G 2 92  ? -0.524  -5.033  -1.340 1.00 33.69  ? 110 THR H CB  1 
ATOM   19434 O OG1 . THR G 2 92  ? -1.170  -6.134  -1.980 1.00 33.69  ? 110 THR H OG1 1 
ATOM   19435 C CG2 . THR G 2 92  ? 0.943   -5.347  -1.170 1.00 33.69  ? 110 THR H CG2 1 
ATOM   19436 N N   . ALA G 2 93  ? 0.009   -3.552  1.708  1.00 23.65  ? 111 ALA H N   1 
ATOM   19437 C CA  . ALA G 2 93  ? 0.518   -2.390  2.408  1.00 23.65  ? 111 ALA H CA  1 
ATOM   19438 C C   . ALA G 2 93  ? 1.508   -2.820  3.461  1.00 23.65  ? 111 ALA H C   1 
ATOM   19439 O O   . ALA G 2 93  ? 1.742   -4.000  3.649  1.00 23.65  ? 111 ALA H O   1 
ATOM   19440 C CB  . ALA G 2 93  ? -0.623  -1.641  3.073  1.00 24.20  ? 111 ALA H CB  1 
ATOM   19441 N N   . VAL G 2 94  ? 2.125   -1.848  4.114  1.00 19.56  ? 112 VAL H N   1 
ATOM   19442 C CA  . VAL G 2 94  ? 3.012   -2.126  5.223  1.00 19.56  ? 112 VAL H CA  1 
ATOM   19443 C C   . VAL G 2 94  ? 2.162   -1.759  6.428  1.00 19.56  ? 112 VAL H C   1 
ATOM   19444 O O   . VAL G 2 94  ? 1.760   -0.620  6.558  1.00 19.56  ? 112 VAL H O   1 
ATOM   19445 C CB  . VAL G 2 94  ? 4.261   -1.241  5.187  1.00 19.13  ? 112 VAL H CB  1 
ATOM   19446 C CG1 . VAL G 2 94  ? 5.035   -1.356  6.485  1.00 19.13  ? 112 VAL H CG1 1 
ATOM   19447 C CG2 . VAL G 2 94  ? 5.134   -1.611  4.005  1.00 19.13  ? 112 VAL H CG2 1 
ATOM   19448 N N   . TYR G 2 95  ? 1.856   -2.716  7.293  1.00 18.81  ? 113 TYR H N   1 
ATOM   19449 C CA  . TYR G 2 95  ? 1.022   -2.433  8.454  1.00 18.81  ? 113 TYR H CA  1 
ATOM   19450 C C   . TYR G 2 95  ? 1.839   -2.077  9.676  1.00 18.81  ? 113 TYR H C   1 
ATOM   19451 O O   . TYR G 2 95  ? 2.816   -2.737  9.989  1.00 18.81  ? 113 TYR H O   1 
ATOM   19452 C CB  . TYR G 2 95  ? 0.114   -3.619  8.762  1.00 21.14  ? 113 TYR H CB  1 
ATOM   19453 C CG  . TYR G 2 95  ? -1.017  -3.774  7.782  1.00 21.14  ? 113 TYR H CG  1 
ATOM   19454 C CD1 . TYR G 2 95  ? -2.315  -3.480  8.144  1.00 21.14  ? 113 TYR H CD1 1 
ATOM   19455 C CD2 . TYR G 2 95  ? -0.781  -4.206  6.493  1.00 21.14  ? 113 TYR H CD2 1 
ATOM   19456 C CE1 . TYR G 2 95  ? -3.348  -3.619  7.246  1.00 21.14  ? 113 TYR H CE1 1 
ATOM   19457 C CE2 . TYR G 2 95  ? -1.805  -4.343  5.589  1.00 21.14  ? 113 TYR H CE2 1 
ATOM   19458 C CZ  . TYR G 2 95  ? -3.083  -4.046  5.972  1.00 21.14  ? 113 TYR H CZ  1 
ATOM   19459 O OH  . TYR G 2 95  ? -4.101  -4.184  5.071  1.00 21.14  ? 113 TYR H OH  1 
ATOM   19460 N N   . TYR G 2 96  ? 1.425   -1.036  10.382 1.00 15.90  ? 114 TYR H N   1 
ATOM   19461 C CA  . TYR G 2 96  ? 2.153   -0.611  11.564 1.00 15.90  ? 114 TYR H CA  1 
ATOM   19462 C C   . TYR G 2 96  ? 1.304   -0.829  12.807 1.00 15.90  ? 114 TYR H C   1 
ATOM   19463 O O   . TYR G 2 96  ? 0.073   -0.821  12.760 1.00 15.90  ? 114 TYR H O   1 
ATOM   19464 C CB  . TYR G 2 96  ? 2.552   0.868   11.496 1.00 17.78  ? 114 TYR H CB  1 
ATOM   19465 C CG  . TYR G 2 96  ? 3.485   1.237   10.373 1.00 17.78  ? 114 TYR H CG  1 
ATOM   19466 C CD1 . TYR G 2 96  ? 4.856   1.137   10.523 1.00 17.78  ? 114 TYR H CD1 1 
ATOM   19467 C CD2 . TYR G 2 96  ? 2.991   1.714   9.172  1.00 17.78  ? 114 TYR H CD2 1 
ATOM   19468 C CE1 . TYR G 2 96  ? 5.708   1.487   9.500  1.00 17.78  ? 114 TYR H CE1 1 
ATOM   19469 C CE2 . TYR G 2 96  ? 3.831   2.061   8.148  1.00 17.78  ? 114 TYR H CE2 1 
ATOM   19470 C CZ  . TYR G 2 96  ? 5.189   1.948   8.315  1.00 17.78  ? 114 TYR H CZ  1 
ATOM   19471 O OH  . TYR G 2 96  ? 6.034   2.299   7.288  1.00 17.78  ? 114 TYR H OH  1 
ATOM   19472 N N   . CYS G 2 97  ? 1.986   -0.952  13.930 1.00 15.99  ? 115 CYS H N   1 
ATOM   19473 C CA  . CYS G 2 97  ? 1.351   -1.096  15.213 1.00 15.99  ? 115 CYS H CA  1 
ATOM   19474 C C   . CYS G 2 97  ? 1.658   0.228   15.896 1.00 15.99  ? 115 CYS H C   1 
ATOM   19475 O O   . CYS G 2 97  ? 2.812   0.559   16.098 1.00 15.99  ? 115 CYS H O   1 
ATOM   19476 C CB  . CYS G 2 97  ? 1.981   -2.258  15.966 1.00 20.57  ? 115 CYS H CB  1 
ATOM   19477 S SG  . CYS G 2 97  ? 1.272   -2.578  17.588 1.00 20.57  ? 115 CYS H SG  1 
ATOM   19478 N N   . ALA G 2 98  ? 0.634   1.008   16.213 1.00 13.18  ? 116 ALA H N   1 
ATOM   19479 C CA  . ALA G 2 98  ? 0.840   2.298   16.857 1.00 13.18  ? 116 ALA H CA  1 
ATOM   19480 C C   . ALA G 2 98  ? 0.209   2.349   18.239 1.00 13.18  ? 116 ALA H C   1 
ATOM   19481 O O   . ALA G 2 98  ? -0.946  1.997   18.416 1.00 13.18  ? 116 ALA H O   1 
ATOM   19482 C CB  . ALA G 2 98  ? 0.301   3.417   15.987 1.00 11.27  ? 116 ALA H CB  1 
ATOM   19483 N N   . LYS G 2 99  ? 0.977   2.808   19.216 1.00 12.35  ? 117 LYS H N   1 
ATOM   19484 C CA  . LYS G 2 99  ? 0.505   2.896   20.584 1.00 12.35  ? 117 LYS H CA  1 
ATOM   19485 C C   . LYS G 2 99  ? -0.078  4.263   20.843 1.00 12.35  ? 117 LYS H C   1 
ATOM   19486 O O   . LYS G 2 99  ? 0.560   5.261   20.556 1.00 12.35  ? 117 LYS H O   1 
ATOM   19487 C CB  . LYS G 2 99  ? 1.663   2.673   21.541 1.00 13.27  ? 117 LYS H CB  1 
ATOM   19488 C CG  . LYS G 2 99  ? 1.310   2.924   22.987 1.00 13.27  ? 117 LYS H CG  1 
ATOM   19489 C CD  . LYS G 2 99  ? 2.524   2.773   23.872 1.00 13.27  ? 117 LYS H CD  1 
ATOM   19490 C CE  . LYS G 2 99  ? 3.180   4.110   24.113 1.00 13.27  ? 117 LYS H CE  1 
ATOM   19491 N NZ  . LYS G 2 99  ? 2.424   4.901   25.113 1.00 13.27  ? 117 LYS H NZ  1 
ATOM   19492 N N   . GLY G 2 100 ? -1.237  4.252   21.492 1.00 13.49  ? 118 GLY H N   1 
ATOM   19493 C CA  . GLY G 2 100 ? -1.923  5.441   21.919 1.00 13.49  ? 118 GLY H CA  1 
ATOM   19494 C C   . GLY G 2 100 ? -1.133  6.102   23.034 1.00 13.49  ? 118 GLY H C   1 
ATOM   19495 O O   . GLY G 2 100 ? -0.847  5.496   24.059 1.00 13.49  ? 118 GLY H O   1 
ATOM   19496 N N   . MET G 2 101 ? -0.750  7.345   22.800 1.00 15.64  ? 119 MET H N   1 
ATOM   19497 C CA  . MET G 2 101 ? 0.011   8.170   23.716 1.00 15.64  ? 119 MET H CA  1 
ATOM   19498 C C   . MET G 2 101 ? -0.668  8.532   25.028 1.00 15.64  ? 119 MET H C   1 
ATOM   19499 O O   . MET G 2 101 ? -0.046  8.491   26.077 1.00 15.64  ? 119 MET H O   1 
ATOM   19500 C CB  . MET G 2 101 ? 0.378   9.461   22.999 1.00 19.62  ? 119 MET H CB  1 
ATOM   19501 C CG  . MET G 2 101 ? 0.953   10.533  23.894 1.00 19.62  ? 119 MET H CG  1 
ATOM   19502 S SD  . MET G 2 101 ? 1.167   12.059  22.976 1.00 19.62  ? 119 MET H SD  1 
ATOM   19503 C CE  . MET G 2 101 ? 2.242   12.959  24.081 1.00 19.62  ? 119 MET H CE  1 
ATOM   19504 N N   . SER G 2 102 ? -1.941  8.892   24.977 1.00 13.57  ? 120 SER H N   1 
ATOM   19505 C CA  . SER G 2 102 ? -2.646  9.281   26.187 1.00 13.57  ? 120 SER H CA  1 
ATOM   19506 C C   . SER G 2 102 ? -2.845  8.106   27.125 1.00 13.57  ? 120 SER H C   1 
ATOM   19507 O O   . SER G 2 102 ? -3.168  7.013   26.691 1.00 13.57  ? 120 SER H O   1 
ATOM   19508 C CB  . SER G 2 102 ? -3.985  9.908   25.834 1.00 11.30  ? 120 SER H CB  1 
ATOM   19509 O OG  . SER G 2 102 ? -4.568  10.508  26.969 1.00 11.30  ? 120 SER H OG  1 
ATOM   19510 N N   . TYR G 2 103 ? -2.690  8.342   28.418 1.00 14.61  ? 121 TYR H N   1 
ATOM   19511 C CA  . TYR G 2 103 ? -2.842  7.285   29.403 1.00 14.61  ? 121 TYR H CA  1 
ATOM   19512 C C   . TYR G 2 103 ? -4.102  7.484   30.217 1.00 14.61  ? 121 TYR H C   1 
ATOM   19513 O O   . TYR G 2 103 ? -4.315  8.540   30.787 1.00 14.61  ? 121 TYR H O   1 
ATOM   19514 C CB  . TYR G 2 103 ? -1.639  7.286   30.338 1.00 17.22  ? 121 TYR H CB  1 
ATOM   19515 C CG  . TYR G 2 103 ? -1.726  6.299   31.475 1.00 17.22  ? 121 TYR H CG  1 
ATOM   19516 C CD1 . TYR G 2 103 ? -1.017  5.113   31.440 1.00 17.22  ? 121 TYR H CD1 1 
ATOM   19517 C CD2 . TYR G 2 103 ? -2.506  6.560   32.586 1.00 17.22  ? 121 TYR H CD2 1 
ATOM   19518 C CE1 . TYR G 2 103 ? -1.088  4.210   32.476 1.00 17.22  ? 121 TYR H CE1 1 
ATOM   19519 C CE2 . TYR G 2 103 ? -2.586  5.662   33.626 1.00 17.22  ? 121 TYR H CE2 1 
ATOM   19520 C CZ  . TYR G 2 103 ? -1.874  4.491   33.562 1.00 17.22  ? 121 TYR H CZ  1 
ATOM   19521 O OH  . TYR G 2 103 ? -1.947  3.594   34.591 1.00 17.22  ? 121 TYR H OH  1 
ATOM   19522 N N   . TYR G 2 104 ? -4.918  6.447   30.324 1.00 15.79  ? 122 TYR H N   1 
ATOM   19523 C CA  . TYR G 2 104 ? -6.135  6.541   31.108 1.00 15.79  ? 122 TYR H CA  1 
ATOM   19524 C C   . TYR G 2 104 ? -6.388  5.247   31.867 1.00 15.79  ? 122 TYR H C   1 
ATOM   19525 O O   . TYR G 2 104 ? -5.696  4.261   31.666 1.00 15.79  ? 122 TYR H O   1 
ATOM   19526 C CB  . TYR G 2 104 ? -7.317  6.893   30.224 1.00 12.28  ? 122 TYR H CB  1 
ATOM   19527 C CG  . TYR G 2 104 ? -7.742  5.774   29.329 1.00 12.28  ? 122 TYR H CG  1 
ATOM   19528 C CD1 . TYR G 2 104 ? -8.884  5.045   29.601 1.00 12.28  ? 122 TYR H CD1 1 
ATOM   19529 C CD2 . TYR G 2 104 ? -6.996  5.439   28.216 1.00 12.28  ? 122 TYR H CD2 1 
ATOM   19530 C CE1 . TYR G 2 104 ? -9.274  4.016   28.784 1.00 12.28  ? 122 TYR H CE1 1 
ATOM   19531 C CE2 . TYR G 2 104 ? -7.380  4.409   27.395 1.00 12.28  ? 122 TYR H CE2 1 
ATOM   19532 C CZ  . TYR G 2 104 ? -8.518  3.706   27.690 1.00 12.28  ? 122 TYR H CZ  1 
ATOM   19533 O OH  . TYR G 2 104 ? -8.911  2.688   26.880 1.00 12.28  ? 122 TYR H OH  1 
ATOM   19534 N N   . ASP G 2 105 ? -7.401  5.246   32.722 1.00 19.15  ? 123 ASP H N   1 
ATOM   19535 C CA  . ASP G 2 105 ? -7.711  4.079   33.539 1.00 19.15  ? 123 ASP H CA  1 
ATOM   19536 C C   . ASP G 2 105 ? -9.189  3.934   33.848 1.00 19.15  ? 123 ASP H C   1 
ATOM   19537 O O   . ASP G 2 105 ? -10.022 4.658   33.323 1.00 19.15  ? 123 ASP H O   1 
ATOM   19538 C CB  . ASP G 2 105 ? -6.910  4.097   34.837 1.00 24.78  ? 123 ASP H CB  1 
ATOM   19539 C CG  . ASP G 2 105 ? -6.941  5.436   35.509 1.00 24.78  ? 123 ASP H CG  1 
ATOM   19540 O OD1 . ASP G 2 105 ? -7.500  6.373   34.915 1.00 24.78  ? 123 ASP H OD1 1 
ATOM   19541 O OD2 . ASP G 2 105 ? -6.405  5.559   36.625 1.00 24.78  ? 123 ASP H OD2 1 
ATOM   19542 N N   . ARG G 2 106 ? -9.496  2.979   34.716 1.00 24.75  ? 124 ARG H N   1 
ATOM   19543 C CA  . ARG G 2 106 ? -10.861 2.672   35.131 1.00 24.75  ? 124 ARG H CA  1 
ATOM   19544 C C   . ARG G 2 106 ? -11.592 3.802   35.841 1.00 24.75  ? 124 ARG H C   1 
ATOM   19545 O O   . ARG G 2 106 ? -12.811 3.841   35.819 1.00 24.75  ? 124 ARG H O   1 
ATOM   19546 C CB  . ARG G 2 106 ? -10.905 1.399   35.967 1.00 33.47  ? 124 ARG H CB  1 
ATOM   19547 C CG  . ARG G 2 106 ? -10.813 0.143   35.128 1.00 33.47  ? 124 ARG H CG  1 
ATOM   19548 C CD  . ARG G 2 106 ? -11.620 -0.984  35.738 1.00 33.47  ? 124 ARG H CD  1 
ATOM   19549 N NE  . ARG G 2 106 ? -11.033 -1.477  36.974 1.00 33.47  ? 124 ARG H NE  1 
ATOM   19550 C CZ  . ARG G 2 106 ? -11.450 -2.569  37.600 1.00 33.47  ? 124 ARG H CZ  1 
ATOM   19551 N NH1 . ARG G 2 106 ? -12.457 -3.270  37.100 1.00 33.47  ? 124 ARG H NH1 1 
ATOM   19552 N NH2 . ARG G 2 106 ? -10.866 -2.961  38.721 1.00 33.47  ? 124 ARG H NH2 1 
ATOM   19553 N N   . SER G 2 107 ? -10.874 4.698   36.509 1.00 20.92  ? 125 SER H N   1 
ATOM   19554 C CA  . SER G 2 107 ? -11.510 5.825   37.178 1.00 20.92  ? 125 SER H CA  1 
ATOM   19555 C C   . SER G 2 107 ? -12.231 6.715   36.161 1.00 20.92  ? 125 SER H C   1 
ATOM   19556 O O   . SER G 2 107 ? -13.313 7.224   36.430 1.00 20.92  ? 125 SER H O   1 
ATOM   19557 C CB  . SER G 2 107 ? -10.479 6.640   37.950 1.00 20.99  ? 125 SER H CB  1 
ATOM   19558 O OG  . SER G 2 107 ? -9.691  7.417   37.073 1.00 20.99  ? 125 SER H OG  1 
ATOM   19559 N N   . GLY G 2 108 ? -11.601 6.929   35.013 1.00 17.66  ? 126 GLY H N   1 
ATOM   19560 C CA  . GLY G 2 108 ? -12.157 7.698   33.918 1.00 17.66  ? 126 GLY H CA  1 
ATOM   19561 C C   . GLY G 2 108 ? -12.868 6.786   32.936 1.00 17.66  ? 126 GLY H C   1 
ATOM   19562 O O   . GLY G 2 108 ? -13.184 5.649   33.253 1.00 17.66  ? 126 GLY H O   1 
ATOM   19563 N N   . TYR G 2 109 ? -13.120 7.304   31.740 1.00 13.48  ? 127 TYR H N   1 
ATOM   19564 C CA  . TYR G 2 109 ? -13.778 6.575   30.653 1.00 13.48  ? 127 TYR H CA  1 
ATOM   19565 C C   . TYR G 2 109 ? -12.871 6.598   29.434 1.00 13.48  ? 127 TYR H C   1 
ATOM   19566 O O   . TYR G 2 109 ? -11.872 7.304   29.422 1.00 13.48  ? 127 TYR H O   1 
ATOM   19567 C CB  . TYR G 2 109 ? -15.108 7.224   30.276 1.00 14.17  ? 127 TYR H CB  1 
ATOM   19568 C CG  . TYR G 2 109 ? -16.124 7.213   31.374 1.00 14.17  ? 127 TYR H CG  1 
ATOM   19569 C CD1 . TYR G 2 109 ? -17.116 6.259   31.411 1.00 14.17  ? 127 TYR H CD1 1 
ATOM   19570 C CD2 . TYR G 2 109 ? -16.084 8.154   32.380 1.00 14.17  ? 127 TYR H CD2 1 
ATOM   19571 C CE1 . TYR G 2 109 ? -18.042 6.242   32.424 1.00 14.17  ? 127 TYR H CE1 1 
ATOM   19572 C CE2 . TYR G 2 109 ? -17.003 8.144   33.397 1.00 14.17  ? 127 TYR H CE2 1 
ATOM   19573 C CZ  . TYR G 2 109 ? -17.980 7.187   33.410 1.00 14.17  ? 127 TYR H CZ  1 
ATOM   19574 O OH  . TYR G 2 109 ? -18.901 7.182   34.423 1.00 14.17  ? 127 TYR H OH  1 
ATOM   19575 N N   . PHE G 2 110 ? -13.143 5.757   28.449 1.00 11.06  ? 128 PHE H N   1 
ATOM   19576 C CA  . PHE G 2 110 ? -12.345 5.787   27.235 1.00 11.06  ? 128 PHE H CA  1 
ATOM   19577 C C   . PHE G 2 110 ? -12.916 6.848   26.304 1.00 11.06  ? 128 PHE H C   1 
ATOM   19578 O O   . PHE G 2 110 ? -14.115 6.863   26.040 1.00 11.06  ? 128 PHE H O   1 
ATOM   19579 C CB  . PHE G 2 110 ? -12.340 4.437   26.546 1.00 10.04  ? 128 PHE H CB  1 
ATOM   19580 C CG  . PHE G 2 110 ? -12.057 4.509   25.079 1.00 10.04  ? 128 PHE H CG  1 
ATOM   19581 C CD1 . PHE G 2 110 ? -10.764 4.582   24.613 1.00 10.04  ? 128 PHE H CD1 1 
ATOM   19582 C CD2 . PHE G 2 110 ? -13.087 4.485   24.167 1.00 10.04  ? 128 PHE H CD2 1 
ATOM   19583 C CE1 . PHE G 2 110 ? -10.503 4.640   23.262 1.00 10.04  ? 128 PHE H CE1 1 
ATOM   19584 C CE2 . PHE G 2 110 ? -12.836 4.540   22.817 1.00 10.04  ? 128 PHE H CE2 1 
ATOM   19585 C CZ  . PHE G 2 110 ? -11.542 4.617   22.364 1.00 10.04  ? 128 PHE H CZ  1 
ATOM   19586 N N   . TRP G 2 111 ? -12.053 7.732   25.815 1.00 10.47  ? 129 TRP H N   1 
ATOM   19587 C CA  . TRP G 2 111 ? -12.452 8.811   24.923 1.00 10.47  ? 129 TRP H CA  1 
ATOM   19588 C C   . TRP G 2 111 ? -11.716 8.665   23.602 1.00 10.47  ? 129 TRP H C   1 
ATOM   19589 O O   . TRP G 2 111 ? -10.496 8.834   23.548 1.00 10.47  ? 129 TRP H O   1 
ATOM   19590 C CB  . TRP G 2 111 ? -12.155 10.164  25.565 1.00 11.45  ? 129 TRP H CB  1 
ATOM   19591 C CG  . TRP G 2 111 ? -13.035 10.426  26.733 1.00 11.45  ? 129 TRP H CG  1 
ATOM   19592 C CD1 . TRP G 2 111 ? -12.830 10.019  28.013 1.00 11.45  ? 129 TRP H CD1 1 
ATOM   19593 C CD2 . TRP G 2 111 ? -14.245 11.188  26.744 1.00 11.45  ? 129 TRP H CD2 1 
ATOM   19594 N NE1 . TRP G 2 111 ? -13.849 10.452  28.818 1.00 11.45  ? 129 TRP H NE1 1 
ATOM   19595 C CE2 . TRP G 2 111 ? -14.730 11.178  28.063 1.00 11.45  ? 129 TRP H CE2 1 
ATOM   19596 C CE3 . TRP G 2 111 ? -14.963 11.879  25.768 1.00 11.45  ? 129 TRP H CE3 1 
ATOM   19597 C CZ2 . TRP G 2 111 ? -15.903 11.824  28.428 1.00 11.45  ? 129 TRP H CZ2 1 
ATOM   19598 C CZ3 . TRP G 2 111 ? -16.131 12.504  26.128 1.00 11.45  ? 129 TRP H CZ3 1 
ATOM   19599 C CH2 . TRP G 2 111 ? -16.588 12.480  27.448 1.00 11.45  ? 129 TRP H CH2 1 
ATOM   19600 N N   . ALA G 2 112 ? -12.460 8.362   22.536 1.00 10.23  ? 130 ALA H N   1 
ATOM   19601 C CA  . ALA G 2 112 ? -11.824 8.076   21.254 1.00 10.23  ? 130 ALA H CA  1 
ATOM   19602 C C   . ALA G 2 112 ? -11.103 9.292   20.695 1.00 10.23  ? 130 ALA H C   1 
ATOM   19603 O O   . ALA G 2 112 ? -10.074 9.147   20.029 1.00 10.23  ? 130 ALA H O   1 
ATOM   19604 C CB  . ALA G 2 112 ? -12.859 7.564   20.254 1.00 7.94   ? 130 ALA H CB  1 
ATOM   19605 N N   . LYS G 2 113 ? -11.626 10.491  20.948 1.00 11.69  ? 131 LYS H N   1 
ATOM   19606 C CA  . LYS G 2 113 ? -10.940 11.710  20.540 1.00 11.69  ? 131 LYS H CA  1 
ATOM   19607 C C   . LYS G 2 113 ? -9.519  11.739  21.082 1.00 11.69  ? 131 LYS H C   1 
ATOM   19608 O O   . LYS G 2 113 ? -8.549  11.894  20.335 1.00 11.69  ? 131 LYS H O   1 
ATOM   19609 C CB  . LYS G 2 113 ? -11.707 12.929  21.048 1.00 18.04  ? 131 LYS H CB  1 
ATOM   19610 C CG  . LYS G 2 113 ? -13.081 13.132  20.474 1.00 18.04  ? 131 LYS H CG  1 
ATOM   19611 C CD  . LYS G 2 113 ? -13.706 14.377  21.080 1.00 18.04  ? 131 LYS H CD  1 
ATOM   19612 C CE  . LYS G 2 113 ? -15.095 14.623  20.530 1.00 18.04  ? 131 LYS H CE  1 
ATOM   19613 N NZ  . LYS G 2 113 ? -15.048 14.879  19.069 1.00 18.04  ? 131 LYS H NZ  1 
ATOM   19614 N N   . TYR G 2 114 ? -9.389  11.599  22.399 1.00 11.66  ? 132 TYR H N   1 
ATOM   19615 C CA  . TYR G 2 114 ? -8.142  11.915  23.079 1.00 11.66  ? 132 TYR H CA  1 
ATOM   19616 C C   . TYR G 2 114 ? -7.156  10.753  23.053 1.00 11.66  ? 132 TYR H C   1 
ATOM   19617 O O   . TYR G 2 114 ? -5.940  10.969  23.034 1.00 11.66  ? 132 TYR H O   1 
ATOM   19618 C CB  . TYR G 2 114 ? -8.467  12.340  24.504 1.00 13.19  ? 132 TYR H CB  1 
ATOM   19619 C CG  . TYR G 2 114 ? -9.436  13.494  24.505 1.00 13.19  ? 132 TYR H CG  1 
ATOM   19620 C CD1 . TYR G 2 114 ? -9.247  14.576  23.661 1.00 13.19  ? 132 TYR H CD1 1 
ATOM   19621 C CD2 . TYR G 2 114 ? -10.580 13.467  25.284 1.00 13.19  ? 132 TYR H CD2 1 
ATOM   19622 C CE1 . TYR G 2 114 ? -10.137 15.621  23.633 1.00 13.19  ? 132 TYR H CE1 1 
ATOM   19623 C CE2 . TYR G 2 114 ? -11.479 14.507  25.257 1.00 13.19  ? 132 TYR H CE2 1 
ATOM   19624 C CZ  . TYR G 2 114 ? -11.251 15.581  24.429 1.00 13.19  ? 132 TYR H CZ  1 
ATOM   19625 O OH  . TYR G 2 114 ? -12.142 16.624  24.400 1.00 13.19  ? 132 TYR H OH  1 
ATOM   19626 N N   . HIS G 2 115 ? -7.663  9.539   23.172 1.00 11.83  ? 133 HIS H N   1 
ATOM   19627 C CA  . HIS G 2 115 ? -6.793  8.382   23.297 1.00 11.83  ? 133 HIS H CA  1 
ATOM   19628 C C   . HIS G 2 115 ? -6.286  7.685   22.045 1.00 11.83  ? 133 HIS H C   1 
ATOM   19629 O O   . HIS G 2 115 ? -5.603  6.673   22.148 1.00 11.83  ? 133 HIS H O   1 
ATOM   19630 C CB  . HIS G 2 115 ? -7.409  7.381   24.275 1.00 10.08  ? 133 HIS H CB  1 
ATOM   19631 C CG  . HIS G 2 115 ? -7.883  8.008   25.549 1.00 10.08  ? 133 HIS H CG  1 
ATOM   19632 N ND1 . HIS G 2 115 ? -9.128  7.764   26.081 1.00 10.08  ? 133 HIS H ND1 1 
ATOM   19633 C CD2 . HIS G 2 115 ? -7.287  8.890   26.383 1.00 10.08  ? 133 HIS H CD2 1 
ATOM   19634 C CE1 . HIS G 2 115 ? -9.274  8.454   27.196 1.00 10.08  ? 133 HIS H CE1 1 
ATOM   19635 N NE2 . HIS G 2 115 ? -8.170  9.147   27.401 1.00 10.08  ? 133 HIS H NE2 1 
ATOM   19636 N N   . TYR G 2 116 ? -6.626  8.189   20.868 1.00 11.90  ? 134 TYR H N   1 
ATOM   19637 C CA  . TYR G 2 116 ? -6.107  7.571   19.661 1.00 11.90  ? 134 TYR H CA  1 
ATOM   19638 C C   . TYR G 2 116 ? -4.832  8.217   19.151 1.00 11.90  ? 134 TYR H C   1 
ATOM   19639 O O   . TYR G 2 116 ? -4.229  7.702   18.237 1.00 11.90  ? 134 TYR H O   1 
ATOM   19640 C CB  . TYR G 2 116 ? -7.146  7.499   18.548 1.00 9.02   ? 134 TYR H CB  1 
ATOM   19641 C CG  . TYR G 2 116 ? -8.112  6.367   18.723 1.00 9.02   ? 134 TYR H CG  1 
ATOM   19642 C CD1 . TYR G 2 116 ? -7.707  5.165   19.274 1.00 9.02   ? 134 TYR H CD1 1 
ATOM   19643 C CD2 . TYR G 2 116 ? -9.426  6.494   18.331 1.00 9.02   ? 134 TYR H CD2 1 
ATOM   19644 C CE1 . TYR G 2 116 ? -8.594  4.128   19.441 1.00 9.02   ? 134 TYR H CE1 1 
ATOM   19645 C CE2 . TYR G 2 116 ? -10.316 5.461   18.490 1.00 9.02   ? 134 TYR H CE2 1 
ATOM   19646 C CZ  . TYR G 2 116 ? -9.892  4.286   19.047 1.00 9.02   ? 134 TYR H CZ  1 
ATOM   19647 O OH  . TYR G 2 116 ? -10.785 3.267   19.203 1.00 9.02   ? 134 TYR H OH  1 
ATOM   19648 N N   . GLY G 2 117 ? -4.403  9.326   19.734 1.00 14.34  ? 135 GLY H N   1 
ATOM   19649 C CA  . GLY G 2 117 ? -3.179  9.948   19.267 1.00 14.34  ? 135 GLY H CA  1 
ATOM   19650 C C   . GLY G 2 117 ? -2.051  8.980   19.527 1.00 14.34  ? 135 GLY H C   1 
ATOM   19651 O O   . GLY G 2 117 ? -1.936  8.452   20.624 1.00 14.34  ? 135 GLY H O   1 
ATOM   19652 N N   . MET G 2 118 ? -1.191  8.775   18.540 1.00 15.02  ? 136 MET H N   1 
ATOM   19653 C CA  . MET G 2 118 ? -0.118  7.800   18.672 1.00 15.02  ? 136 MET H CA  1 
ATOM   19654 C C   . MET G 2 118 ? 1.293   8.368   18.762 1.00 15.02  ? 136 MET H C   1 
ATOM   19655 O O   . MET G 2 118 ? 1.823   8.864   17.780 1.00 15.02  ? 136 MET H O   1 
ATOM   19656 C CB  . MET G 2 118 ? -0.204  6.904   17.445 1.00 16.60  ? 136 MET H CB  1 
ATOM   19657 C CG  . MET G 2 118 ? -0.547  7.714   16.204 1.00 16.60  ? 136 MET H CG  1 
ATOM   19658 S SD  . MET G 2 118 ? -1.504  6.879   14.938 1.00 16.60  ? 136 MET H SD  1 
ATOM   19659 C CE  . MET G 2 118 ? -3.155  7.470   15.221 1.00 16.60  ? 136 MET H CE  1 
ATOM   19660 N N   . ASP G 2 119 ? 1.885   8.324   19.952 1.00 16.31  ? 137 ASP H N   1 
ATOM   19661 C CA  . ASP G 2 119 ? 3.263   8.780   20.150 1.00 16.31  ? 137 ASP H CA  1 
ATOM   19662 C C   . ASP G 2 119 ? 4.373   7.894   19.553 1.00 16.31  ? 137 ASP H C   1 
ATOM   19663 O O   . ASP G 2 119 ? 5.338   8.405   18.991 1.00 16.31  ? 137 ASP H O   1 
ATOM   19664 C CB  . ASP G 2 119 ? 3.550   9.130   21.613 1.00 17.74  ? 137 ASP H CB  1 
ATOM   19665 C CG  . ASP G 2 119 ? 3.463   7.938   22.521 1.00 17.74  ? 137 ASP H CG  1 
ATOM   19666 O OD1 . ASP G 2 119 ? 3.022   6.876   22.050 1.00 17.74  ? 137 ASP H OD1 1 
ATOM   19667 O OD2 . ASP G 2 119 ? 3.832   8.060   23.705 1.00 17.74  ? 137 ASP H OD2 1 
ATOM   19668 N N   . VAL G 2 120 ? 4.236   6.575   19.673 1.00 13.12  ? 138 VAL H N   1 
ATOM   19669 C CA  . VAL G 2 120 ? 5.254   5.660   19.155 1.00 13.12  ? 138 VAL H CA  1 
ATOM   19670 C C   . VAL G 2 120 ? 4.665   4.636   18.207 1.00 13.12  ? 138 VAL H C   1 
ATOM   19671 O O   . VAL G 2 120 ? 3.523   4.239   18.354 1.00 13.12  ? 138 VAL H O   1 
ATOM   19672 C CB  . VAL G 2 120 ? 6.023   4.913   20.264 1.00 15.76  ? 138 VAL H CB  1 
ATOM   19673 C CG1 . VAL G 2 120 ? 5.968   5.672   21.572 1.00 15.76  ? 138 VAL H CG1 1 
ATOM   19674 C CG2 . VAL G 2 120 ? 5.482   3.511   20.446 1.00 15.76  ? 138 VAL H CG2 1 
ATOM   19675 N N   . TRP G 2 121 ? 5.453   4.255   17.211 1.00 13.70  ? 139 TRP H N   1 
ATOM   19676 C CA  . TRP G 2 121 ? 5.028   3.304   16.205 1.00 13.70  ? 139 TRP H CA  1 
ATOM   19677 C C   . TRP G 2 121 ? 5.858   2.042   16.253 1.00 13.70  ? 139 TRP H C   1 
ATOM   19678 O O   . TRP G 2 121 ? 6.659   1.840   17.148 1.00 13.70  ? 139 TRP H O   1 
ATOM   19679 C CB  . TRP G 2 121 ? 5.157   3.915   14.815 1.00 13.13  ? 139 TRP H CB  1 
ATOM   19680 C CG  . TRP G 2 121 ? 4.305   5.109   14.589 1.00 13.13  ? 139 TRP H CG  1 
ATOM   19681 C CD1 . TRP G 2 121 ? 4.356   6.290   15.258 1.00 13.13  ? 139 TRP H CD1 1 
ATOM   19682 C CD2 . TRP G 2 121 ? 3.288   5.255   13.602 1.00 13.13  ? 139 TRP H CD2 1 
ATOM   19683 N NE1 . TRP G 2 121 ? 3.424   7.159   14.764 1.00 13.13  ? 139 TRP H NE1 1 
ATOM   19684 C CE2 . TRP G 2 121 ? 2.755   6.545   13.741 1.00 13.13  ? 139 TRP H CE2 1 
ATOM   19685 C CE3 . TRP G 2 121 ? 2.775   4.422   12.616 1.00 13.13  ? 139 TRP H CE3 1 
ATOM   19686 C CZ2 . TRP G 2 121 ? 1.735   7.016   12.931 1.00 13.13  ? 139 TRP H CZ2 1 
ATOM   19687 C CZ3 . TRP G 2 121 ? 1.766   4.891   11.817 1.00 13.13  ? 139 TRP H CZ3 1 
ATOM   19688 C CH2 . TRP G 2 121 ? 1.255   6.173   11.976 1.00 13.13  ? 139 TRP H CH2 1 
ATOM   19689 N N   . GLY G 2 122 ? 5.681   1.214   15.241 1.00 17.24  ? 140 GLY H N   1 
ATOM   19690 C CA  . GLY G 2 122 ? 6.382   -0.044  15.120 1.00 17.24  ? 140 GLY H CA  1 
ATOM   19691 C C   . GLY G 2 122 ? 7.072   -0.078  13.776 1.00 17.24  ? 140 GLY H C   1 
ATOM   19692 O O   . GLY G 2 122 ? 6.754   0.710   12.892 1.00 17.24  ? 140 GLY H O   1 
ATOM   19693 N N   . GLN G 2 123 ? 8.009   -1.000  13.609 1.00 23.32  ? 141 GLN H N   1 
ATOM   19694 C CA  . GLN G 2 123 ? 8.741   -1.120  12.358 1.00 23.32  ? 141 GLN H CA  1 
ATOM   19695 C C   . GLN G 2 123 ? 7.796   -1.403  11.202 1.00 23.32  ? 141 GLN H C   1 
ATOM   19696 O O   . GLN G 2 123 ? 7.954   -0.873  10.110 1.00 23.32  ? 141 GLN H O   1 
ATOM   19697 C CB  . GLN G 2 123 ? 9.769   -2.241  12.467 1.00 34.82  ? 141 GLN H CB  1 
ATOM   19698 C CG  . GLN G 2 123 ? 10.491  -2.288  13.802 1.00 34.82  ? 141 GLN H CG  1 
ATOM   19699 C CD  . GLN G 2 123 ? 11.415  -3.482  13.925 1.00 34.82  ? 141 GLN H CD  1 
ATOM   19700 O OE1 . GLN G 2 123 ? 11.749  -3.911  15.030 1.00 34.82  ? 141 GLN H OE1 1 
ATOM   19701 N NE2 . GLN G 2 123 ? 11.829  -4.030  12.789 1.00 34.82  ? 141 GLN H NE2 1 
ATOM   19702 N N   . GLY G 2 124 ? 6.814   -2.254  11.459 1.00 22.67  ? 142 GLY H N   1 
ATOM   19703 C CA  . GLY G 2 124 ? 5.824   -2.634  10.472 1.00 22.67  ? 142 GLY H CA  1 
ATOM   19704 C C   . GLY G 2 124 ? 6.178   -3.901  9.724  1.00 22.67  ? 142 GLY H C   1 
ATOM   19705 O O   . GLY G 2 124 ? 7.341   -4.256  9.597  1.00 22.67  ? 142 GLY H O   1 
ATOM   19706 N N   . ILE G 2 125 ? 5.155   -4.588  9.235  1.00 23.06  ? 143 ILE H N   1 
ATOM   19707 C CA  . ILE G 2 125 ? 5.337   -5.808  8.472  1.00 23.06  ? 143 ILE H CA  1 
ATOM   19708 C C   . ILE G 2 125 ? 4.626   -5.656  7.148  1.00 23.06  ? 143 ILE H C   1 
ATOM   19709 O O   . ILE G 2 125 ? 3.457   -5.313  7.116  1.00 23.06  ? 143 ILE H O   1 
ATOM   19710 C CB  . ILE G 2 125 ? 4.734   -7.023  9.187  1.00 22.96  ? 143 ILE H CB  1 
ATOM   19711 C CG1 . ILE G 2 125 ? 3.340   -6.698  9.708  1.00 22.96  ? 143 ILE H CG1 1 
ATOM   19712 C CG2 . ILE G 2 125 ? 5.622   -7.457  10.337 1.00 22.96  ? 143 ILE H CG2 1 
ATOM   19713 C CD1 . ILE G 2 125 ? 3.336   -6.184  11.126 1.00 22.96  ? 143 ILE H CD1 1 
ATOM   19714 N N   . THR G 2 126 ? 5.322   -5.917  6.054  1.00 26.28  ? 144 THR H N   1 
ATOM   19715 C CA  . THR G 2 126 ? 4.706   -5.799  4.749  1.00 26.28  ? 144 THR H CA  1 
ATOM   19716 C C   . THR G 2 126 ? 3.698   -6.912  4.553  1.00 26.28  ? 144 THR H C   1 
ATOM   19717 O O   . THR G 2 126 ? 3.952   -8.048  4.929  1.00 26.28  ? 144 THR H O   1 
ATOM   19718 C CB  . THR G 2 126 ? 5.752   -5.879  3.631  1.00 25.59  ? 144 THR H CB  1 
ATOM   19719 O OG1 . THR G 2 126 ? 6.813   -4.955  3.899  1.00 25.59  ? 144 THR H OG1 1 
ATOM   19720 C CG2 . THR G 2 126 ? 5.122   -5.544  2.298  1.00 25.59  ? 144 THR H CG2 1 
ATOM   19721 N N   . VAL G 2 127 ? 2.547   -6.588  3.981  1.00 28.07  ? 145 VAL H N   1 
ATOM   19722 C CA  . VAL G 2 127 ? 1.535   -7.593  3.709  1.00 28.07  ? 145 VAL H CA  1 
ATOM   19723 C C   . VAL G 2 127 ? 1.208   -7.523  2.233  1.00 28.07  ? 145 VAL H C   1 
ATOM   19724 O O   . VAL G 2 127 ? 0.893   -6.458  1.722  1.00 28.07  ? 145 VAL H O   1 
ATOM   19725 C CB  . VAL G 2 127 ? 0.259   -7.346  4.520  1.00 26.42  ? 145 VAL H CB  1 
ATOM   19726 C CG1 . VAL G 2 127 ? -0.813  -8.351  4.141  1.00 26.42  ? 145 VAL H CG1 1 
ATOM   19727 C CG2 . VAL G 2 127 ? 0.560   -7.414  6.004  1.00 26.42  ? 145 VAL H CG2 1 
ATOM   19728 N N   . THR G 2 128 ? 1.277   -8.649  1.539  1.00 34.13  ? 146 THR H N   1 
ATOM   19729 C CA  . THR G 2 128 ? 0.987   -8.644  0.116  1.00 34.13  ? 146 THR H CA  1 
ATOM   19730 C C   . THR G 2 128 ? -0.153  -9.582  -0.233 1.00 34.13  ? 146 THR H C   1 
ATOM   19731 O O   . THR G 2 128 ? -0.150  -10.743 0.157  1.00 34.13  ? 146 THR H O   1 
ATOM   19732 C CB  . THR G 2 128 ? 2.227   -9.017  -0.708 1.00 33.64  ? 146 THR H CB  1 
ATOM   19733 O OG1 . THR G 2 128 ? 3.388   -8.414  -0.126 1.00 33.64  ? 146 THR H OG1 1 
ATOM   19734 C CG2 . THR G 2 128 ? 2.079   -8.529  -2.131 1.00 33.64  ? 146 THR H CG2 1 
ATOM   19735 N N   . VAL G 2 129 ? -1.126  -9.074  -0.975 1.00 40.26  ? 147 VAL H N   1 
ATOM   19736 C CA  . VAL G 2 129 ? -2.266  -9.869  -1.391 1.00 40.26  ? 147 VAL H CA  1 
ATOM   19737 C C   . VAL G 2 129 ? -2.244  -9.940  -2.905 1.00 40.26  ? 147 VAL H C   1 
ATOM   19738 O O   . VAL G 2 129 ? -2.709  -9.032  -3.582 1.00 40.26  ? 147 VAL H O   1 
ATOM   19739 C CB  . VAL G 2 129 ? -3.584  -9.236  -0.929 1.00 39.11  ? 147 VAL H CB  1 
ATOM   19740 C CG1 . VAL G 2 129 ? -4.764  -9.969  -1.536 1.00 39.11  ? 147 VAL H CG1 1 
ATOM   19741 C CG2 . VAL G 2 129 ? -3.664  -9.239  0.585  1.00 39.11  ? 147 VAL H CG2 1 
ATOM   19742 N N   . SER G 2 130 ? -1.711  -11.031 -3.434 1.00 47.47  ? 148 SER H N   1 
ATOM   19743 C CA  . SER G 2 130 ? -1.577  -11.188 -4.873 1.00 47.47  ? 148 SER H CA  1 
ATOM   19744 C C   . SER G 2 130 ? -1.950  -12.609 -5.259 1.00 47.47  ? 148 SER H C   1 
ATOM   19745 O O   . SER G 2 130 ? -1.860  -13.537 -4.453 1.00 47.47  ? 148 SER H O   1 
ATOM   19746 C CB  . SER G 2 130 ? -0.156  -10.864 -5.344 1.00 47.47  ? 148 SER H CB  1 
ATOM   19747 O OG  . SER G 2 130 ? 0.777   -11.771 -4.790 1.00 47.47  ? 148 SER H OG  1 
ATOM   19748 N N   . SER G 2 131 ? -2.360  -12.768 -6.512 1.00 53.81  ? 149 SER H N   1 
ATOM   19749 C CA  . SER G 2 131 ? -2.773  -14.067 -7.023 1.00 53.81  ? 149 SER H CA  1 
ATOM   19750 C C   . SER G 2 131 ? -1.569  -14.953 -7.323 1.00 53.81  ? 149 SER H C   1 
ATOM   19751 O O   . SER G 2 131 ? -0.450  -14.477 -7.505 1.00 53.81  ? 149 SER H O   1 
ATOM   19752 C CB  . SER G 2 131 ? -3.628  -13.896 -8.278 1.00 57.39  ? 149 SER H CB  1 
ATOM   19753 O OG  . SER G 2 131 ? -4.017  -15.152 -8.803 1.00 57.39  ? 149 SER H OG  1 
ATOM   19754 O OXT . SER G 2 131 ? -1.687  -16.175 -7.386 1.00 57.39  ? 149 SER H OXT 1 
ATOM   19755 N N   . VAL H 3 1   ? -11.075 13.547  4.653  1.00 30.52  ? 23  VAL L N   1 
ATOM   19756 C CA  . VAL H 3 1   ? -9.620  13.617  4.613  1.00 30.52  ? 23  VAL L CA  1 
ATOM   19757 C C   . VAL H 3 1   ? -9.095  15.015  4.897  1.00 30.52  ? 23  VAL L C   1 
ATOM   19758 O O   . VAL H 3 1   ? -9.833  15.997  4.841  1.00 30.52  ? 23  VAL L O   1 
ATOM   19759 C CB  . VAL H 3 1   ? -9.063  13.183  3.247  1.00 31.86  ? 23  VAL L CB  1 
ATOM   19760 C CG1 . VAL H 3 1   ? -9.013  11.669  3.137  1.00 31.86  ? 23  VAL L CG1 1 
ATOM   19761 C CG2 . VAL H 3 1   ? -9.872  13.800  2.119  1.00 31.86  ? 23  VAL L CG2 1 
ATOM   19762 N N   . LEU H 3 2   ? -7.803  15.087  5.191  1.00 30.34  ? 24  LEU L N   1 
ATOM   19763 C CA  . LEU H 3 2   ? -7.136  16.345  5.468  1.00 30.34  ? 24  LEU L CA  1 
ATOM   19764 C C   . LEU H 3 2   ? -6.279  16.627  4.251  1.00 30.34  ? 24  LEU L C   1 
ATOM   19765 O O   . LEU H 3 2   ? -5.508  15.781  3.819  1.00 30.34  ? 24  LEU L O   1 
ATOM   19766 C CB  . LEU H 3 2   ? -6.279  16.226  6.723  1.00 23.09  ? 24  LEU L CB  1 
ATOM   19767 C CG  . LEU H 3 2   ? -7.035  15.737  7.952  1.00 23.09  ? 24  LEU L CG  1 
ATOM   19768 C CD1 . LEU H 3 2   ? -6.089  15.456  9.099  1.00 23.09  ? 24  LEU L CD1 1 
ATOM   19769 C CD2 . LEU H 3 2   ? -8.061  16.775  8.354  1.00 23.09  ? 24  LEU L CD2 1 
ATOM   19770 N N   . THR H 3 3   ? -6.426  17.817  3.688  1.00 31.54  ? 25  THR L N   1 
ATOM   19771 C CA  . THR H 3 3   ? -5.700  18.178  2.483  1.00 31.54  ? 25  THR L CA  1 
ATOM   19772 C C   . THR H 3 3   ? -4.366  18.842  2.735  1.00 31.54  ? 25  THR L C   1 
ATOM   19773 O O   . THR H 3 3   ? -4.280  19.795  3.494  1.00 31.54  ? 25  THR L O   1 
ATOM   19774 C CB  . THR H 3 3   ? -6.541  19.122  1.613  1.00 33.38  ? 25  THR L CB  1 
ATOM   19775 O OG1 . THR H 3 3   ? -7.785  18.491  1.294  1.00 33.38  ? 25  THR L OG1 1 
ATOM   19776 C CG2 . THR H 3 3   ? -5.808  19.463  0.334  1.00 33.38  ? 25  THR L CG2 1 
ATOM   19777 N N   . GLN H 3 4   ? -3.325  18.328  2.092  1.00 31.91  ? 26  GLN L N   1 
ATOM   19778 C CA  . GLN H 3 4   ? -1.995  18.904  2.211  1.00 31.91  ? 26  GLN L CA  1 
ATOM   19779 C C   . GLN H 3 4   ? -1.369  19.104  0.842  1.00 31.91  ? 26  GLN L C   1 
ATOM   19780 O O   . GLN H 3 4   ? -1.653  18.350  -0.085 1.00 31.91  ? 26  GLN L O   1 
ATOM   19781 C CB  . GLN H 3 4   ? -1.084  17.956  2.984  1.00 25.28  ? 26  GLN L CB  1 
ATOM   19782 C CG  . GLN H 3 4   ? -1.342  17.846  4.468  1.00 25.28  ? 26  GLN L CG  1 
ATOM   19783 C CD  . GLN H 3 4   ? -0.214  17.127  5.166  1.00 25.28  ? 26  GLN L CD  1 
ATOM   19784 O OE1 . GLN H 3 4   ? -0.154  15.903  5.173  1.00 25.28  ? 26  GLN L OE1 1 
ATOM   19785 N NE2 . GLN H 3 4   ? 0.696   17.886  5.745  1.00 25.28  ? 26  GLN L NE2 1 
ATOM   19786 N N   . PRO H 3 5   ? -0.512  20.125  0.701  1.00 32.17  ? 27  PRO L N   1 
ATOM   19787 C CA  . PRO H 3 5   ? 0.173   20.309  -0.579 1.00 32.17  ? 27  PRO L CA  1 
ATOM   19788 C C   . PRO H 3 5   ? 1.090   19.111  -0.791 1.00 32.17  ? 27  PRO L C   1 
ATOM   19789 O O   . PRO H 3 5   ? 1.739   18.673  0.153  1.00 32.17  ? 27  PRO L O   1 
ATOM   19790 C CB  . PRO H 3 5   ? 0.989   21.586  -0.367 1.00 32.11  ? 27  PRO L CB  1 
ATOM   19791 C CG  . PRO H 3 5   ? 1.060   21.775  1.106  1.00 32.11  ? 27  PRO L CG  1 
ATOM   19792 C CD  . PRO H 3 5   ? -0.201  21.195  1.657  1.00 32.11  ? 27  PRO L CD  1 
ATOM   19793 N N   . PRO H 3 6   ? 1.193   18.612  -2.025 1.00 34.27  ? 28  PRO L N   1 
ATOM   19794 C CA  . PRO H 3 6   ? 2.013   17.419  -2.247 1.00 34.27  ? 28  PRO L CA  1 
ATOM   19795 C C   . PRO H 3 6   ? 3.472   17.612  -1.874 1.00 34.27  ? 28  PRO L C   1 
ATOM   19796 O O   . PRO H 3 6   ? 4.067   16.688  -1.328 1.00 34.27  ? 28  PRO L O   1 
ATOM   19797 C CB  . PRO H 3 6   ? 1.887   17.188  -3.752 1.00 34.93  ? 28  PRO L CB  1 
ATOM   19798 C CG  . PRO H 3 6   ? 0.609   17.847  -4.126 1.00 34.93  ? 28  PRO L CG  1 
ATOM   19799 C CD  . PRO H 3 6   ? 0.530   19.061  -3.255 1.00 34.93  ? 28  PRO L CD  1 
ATOM   19800 N N   . SER H 3 7   ? 4.045   18.770  -2.178 1.00 36.31  ? 29  SER L N   1 
ATOM   19801 C CA  . SER H 3 7   ? 5.439   19.023  -1.842 1.00 36.31  ? 29  SER L CA  1 
ATOM   19802 C C   . SER H 3 7   ? 5.687   20.445  -1.367 1.00 36.31  ? 29  SER L C   1 
ATOM   19803 O O   . SER H 3 7   ? 4.946   21.360  -1.701 1.00 36.31  ? 29  SER L O   1 
ATOM   19804 C CB  . SER H 3 7   ? 6.336   18.714  -3.034 1.00 37.85  ? 29  SER L CB  1 
ATOM   19805 O OG  . SER H 3 7   ? 5.976   19.509  -4.143 1.00 37.85  ? 29  SER L OG  1 
ATOM   19806 N N   . ALA H 3 8   ? 6.736   20.611  -0.573 1.00 39.29  ? 30  ALA L N   1 
ATOM   19807 C CA  . ALA H 3 8   ? 7.134   21.909  -0.052 1.00 39.29  ? 30  ALA L CA  1 
ATOM   19808 C C   . ALA H 3 8   ? 8.637   22.027  -0.243 1.00 39.29  ? 30  ALA L C   1 
ATOM   19809 O O   . ALA H 3 8   ? 9.340   21.023  -0.209 1.00 39.29  ? 30  ALA L O   1 
ATOM   19810 C CB  . ALA H 3 8   ? 6.771   22.027  1.415  1.00 32.17  ? 30  ALA L CB  1 
ATOM   19811 N N   . SER H 3 9   ? 9.140   23.238  -0.445 1.00 43.50  ? 31  SER L N   1 
ATOM   19812 C CA  . SER H 3 9   ? 10.573  23.415  -0.651 1.00 43.50  ? 31  SER L CA  1 
ATOM   19813 C C   . SER H 3 9   ? 11.157  24.506  0.229  1.00 43.50  ? 31  SER L C   1 
ATOM   19814 O O   . SER H 3 9   ? 10.462  25.425  0.648  1.00 43.50  ? 31  SER L O   1 
ATOM   19815 C CB  . SER H 3 9   ? 10.884  23.710  -2.116 1.00 47.10  ? 31  SER L CB  1 
ATOM   19816 O OG  . SER H 3 9   ? 10.756  25.091  -2.390 1.00 47.10  ? 31  SER L OG  1 
ATOM   19817 N N   . GLY H 3 10  ? 12.442  24.384  0.518  1.00 47.19  ? 32  GLY L N   1 
ATOM   19818 C CA  . GLY H 3 10  ? 13.124  25.346  1.356  1.00 47.19  ? 32  GLY L CA  1 
ATOM   19819 C C   . GLY H 3 10  ? 14.623  25.372  1.151  1.00 47.19  ? 32  GLY L C   1 
ATOM   19820 O O   . GLY H 3 10  ? 15.186  24.515  0.479  1.00 47.19  ? 32  GLY L O   1 
ATOM   19821 N N   . THR H 3 11  ? 15.262  26.387  1.712  1.00 51.24  ? 33  THR L N   1 
ATOM   19822 C CA  . THR H 3 11  ? 16.711  26.528  1.656  1.00 51.24  ? 33  THR L CA  1 
ATOM   19823 C C   . THR H 3 11  ? 17.187  26.442  3.102  1.00 51.24  ? 33  THR L C   1 
ATOM   19824 O O   . THR H 3 11  ? 16.463  26.840  4.013  1.00 51.24  ? 33  THR L O   1 
ATOM   19825 C CB  . THR H 3 11  ? 17.138  27.866  1.032  1.00 54.69  ? 33  THR L CB  1 
ATOM   19826 O OG1 . THR H 3 11  ? 16.414  28.080  -0.184 1.00 54.69  ? 33  THR L OG1 1 
ATOM   19827 C CG2 . THR H 3 11  ? 18.621  27.859  0.724  1.00 54.69  ? 33  THR L CG2 1 
ATOM   19828 N N   . PRO H 3 12  ? 18.404  25.927  3.326  1.00 48.76  ? 34  PRO L N   1 
ATOM   19829 C CA  . PRO H 3 12  ? 18.867  25.786  4.710  1.00 48.76  ? 34  PRO L CA  1 
ATOM   19830 C C   . PRO H 3 12  ? 18.887  27.115  5.452  1.00 48.76  ? 34  PRO L C   1 
ATOM   19831 O O   . PRO H 3 12  ? 19.355  28.116  4.922  1.00 48.76  ? 34  PRO L O   1 
ATOM   19832 C CB  . PRO H 3 12  ? 20.292  25.257  4.546  1.00 48.90  ? 34  PRO L CB  1 
ATOM   19833 C CG  . PRO H 3 12  ? 20.289  24.574  3.222  1.00 48.90  ? 34  PRO L CG  1 
ATOM   19834 C CD  . PRO H 3 12  ? 19.363  25.375  2.357  1.00 48.90  ? 34  PRO L CD  1 
ATOM   19835 N N   . GLY H 3 13  ? 18.384  27.103  6.682  1.00 46.44  ? 35  GLY L N   1 
ATOM   19836 C CA  . GLY H 3 13  ? 18.309  28.300  7.497  1.00 46.44  ? 35  GLY L CA  1 
ATOM   19837 C C   . GLY H 3 13  ? 17.097  29.170  7.199  1.00 46.44  ? 35  GLY L C   1 
ATOM   19838 O O   . GLY H 3 13  ? 16.981  30.274  7.725  1.00 46.44  ? 35  GLY L O   1 
ATOM   19839 N N   . GLN H 3 14  ? 16.187  28.673  6.366  1.00 45.79  ? 36  GLN L N   1 
ATOM   19840 C CA  . GLN H 3 14  ? 14.985  29.423  5.997  1.00 45.79  ? 36  GLN L CA  1 
ATOM   19841 C C   . GLN H 3 14  ? 13.700  28.756  6.474  1.00 45.79  ? 36  GLN L C   1 
ATOM   19842 O O   . GLN H 3 14  ? 13.550  27.547  6.364  1.00 45.79  ? 36  GLN L O   1 
ATOM   19843 C CB  . GLN H 3 14  ? 14.914  29.622  4.485  1.00 55.42  ? 36  GLN L CB  1 
ATOM   19844 C CG  . GLN H 3 14  ? 15.726  30.793  3.962  1.00 55.42  ? 36  GLN L CG  1 
ATOM   19845 C CD  . GLN H 3 14  ? 15.322  31.178  2.554  1.00 55.42  ? 36  GLN L CD  1 
ATOM   19846 O OE1 . GLN H 3 14  ? 14.299  30.719  2.043  1.00 55.42  ? 36  GLN L OE1 1 
ATOM   19847 N NE2 . GLN H 3 14  ? 16.123  32.024  1.919  1.00 55.42  ? 36  GLN L NE2 1 
ATOM   19848 N N   . ARG H 3 15  ? 12.781  29.545  7.020  1.00 39.89  ? 37  ARG L N   1 
ATOM   19849 C CA  . ARG H 3 15  ? 11.515  29.011  7.508  1.00 39.89  ? 37  ARG L CA  1 
ATOM   19850 C C   . ARG H 3 15  ? 10.626  28.447  6.398  1.00 39.89  ? 37  ARG L C   1 
ATOM   19851 O O   . ARG H 3 15  ? 10.481  29.050  5.343  1.00 39.89  ? 37  ARG L O   1 
ATOM   19852 C CB  . ARG H 3 15  ? 10.760  30.081  8.298  1.00 40.15  ? 37  ARG L CB  1 
ATOM   19853 C CG  . ARG H 3 15  ? 9.385   29.652  8.781  1.00 40.15  ? 37  ARG L CG  1 
ATOM   19854 C CD  . ARG H 3 15  ? 8.728   30.718  9.632  1.00 40.15  ? 37  ARG L CD  1 
ATOM   19855 N NE  . ARG H 3 15  ? 7.376   30.337  10.021 1.00 40.15  ? 37  ARG L NE  1 
ATOM   19856 C CZ  . ARG H 3 15  ? 6.655   30.990  10.924 1.00 40.15  ? 37  ARG L CZ  1 
ATOM   19857 N NH1 . ARG H 3 15  ? 5.430   30.584  11.226 1.00 40.15  ? 37  ARG L NH1 1 
ATOM   19858 N NH2 . ARG H 3 15  ? 7.165   32.051  11.529 1.00 40.15  ? 37  ARG L NH2 1 
ATOM   19859 N N   . VAL H 3 16  ? 10.031  27.287  6.659  1.00 36.00  ? 38  VAL L N   1 
ATOM   19860 C CA  . VAL H 3 16  ? 9.135   26.612  5.729  1.00 36.00  ? 38  VAL L CA  1 
ATOM   19861 C C   . VAL H 3 16  ? 7.832   26.287  6.452  1.00 36.00  ? 38  VAL L C   1 
ATOM   19862 O O   . VAL H 3 16  ? 7.853   25.881  7.608  1.00 36.00  ? 38  VAL L O   1 
ATOM   19863 C CB  . VAL H 3 16  ? 9.754   25.299  5.220  1.00 35.11  ? 38  VAL L CB  1 
ATOM   19864 C CG1 . VAL H 3 16  ? 8.844   24.636  4.203  1.00 35.11  ? 38  VAL L CG1 1 
ATOM   19865 C CG2 . VAL H 3 16  ? 11.118  25.562  4.613  1.00 35.11  ? 38  VAL L CG2 1 
ATOM   19866 N N   . THR H 3 17  ? 6.697   26.480  5.790  1.00 31.28  ? 39  THR L N   1 
ATOM   19867 C CA  . THR H 3 17  ? 5.416   26.182  6.412  1.00 31.28  ? 39  THR L CA  1 
ATOM   19868 C C   . THR H 3 17  ? 4.631   25.135  5.632  1.00 31.28  ? 39  THR L C   1 
ATOM   19869 O O   . THR H 3 17  ? 4.481   25.237  4.422  1.00 31.28  ? 39  THR L O   1 
ATOM   19870 C CB  . THR H 3 17  ? 4.565   27.457  6.578  1.00 34.37  ? 39  THR L CB  1 
ATOM   19871 O OG1 . THR H 3 17  ? 5.200   28.337  7.510  1.00 34.37  ? 39  THR L OG1 1 
ATOM   19872 C CG2 . THR H 3 17  ? 3.178   27.125  7.094  1.00 34.37  ? 39  THR L CG2 1 
ATOM   19873 N N   . ILE H 3 18  ? 4.147   24.120  6.342  1.00 29.89  ? 40  ILE L N   1 
ATOM   19874 C CA  . ILE H 3 18  ? 3.342   23.051  5.764  1.00 29.89  ? 40  ILE L CA  1 
ATOM   19875 C C   . ILE H 3 18  ? 1.979   23.165  6.421  1.00 29.89  ? 40  ILE L C   1 
ATOM   19876 O O   . ILE H 3 18  ? 1.890   23.258  7.638  1.00 29.89  ? 40  ILE L O   1 
ATOM   19877 C CB  . ILE H 3 18  ? 3.934   21.667  6.065  1.00 27.43  ? 40  ILE L CB  1 
ATOM   19878 C CG1 . ILE H 3 18  ? 5.390   21.607  5.606  1.00 27.43  ? 40  ILE L CG1 1 
ATOM   19879 C CG2 . ILE H 3 18  ? 3.112   20.583  5.391  1.00 27.43  ? 40  ILE L CG2 1 
ATOM   19880 C CD1 . ILE H 3 18  ? 6.026   20.248  5.755  1.00 27.43  ? 40  ILE L CD1 1 
ATOM   19881 N N   . SER H 3 19  ? 0.916   23.164  5.630  1.00 29.23  ? 41  SER L N   1 
ATOM   19882 C CA  . SER H 3 19  ? -0.411  23.328  6.199  1.00 29.23  ? 41  SER L CA  1 
ATOM   19883 C C   . SER H 3 19  ? -1.433  22.337  5.704  1.00 29.23  ? 41  SER L C   1 
ATOM   19884 O O   . SER H 3 19  ? -1.381  21.908  4.564  1.00 29.23  ? 41  SER L O   1 
ATOM   19885 C CB  . SER H 3 19  ? -0.922  24.712  5.852  1.00 29.71  ? 41  SER L CB  1 
ATOM   19886 O OG  . SER H 3 19  ? -0.996  24.849  4.449  1.00 29.71  ? 41  SER L OG  1 
ATOM   19887 N N   . CYS H 3 20  ? -2.372  21.979  6.571  1.00 29.54  ? 42  CYS L N   1 
ATOM   19888 C CA  . CYS H 3 20  ? -3.442  21.077  6.179  1.00 29.54  ? 42  CYS L CA  1 
ATOM   19889 C C   . CYS H 3 20  ? -4.813  21.695  6.404  1.00 29.54  ? 42  CYS L C   1 
ATOM   19890 O O   . CYS H 3 20  ? -5.100  22.221  7.472  1.00 29.54  ? 42  CYS L O   1 
ATOM   19891 C CB  . CYS H 3 20  ? -3.329  19.700  6.839  1.00 33.50  ? 42  CYS L CB  1 
ATOM   19892 S SG  . CYS H 3 20  ? -2.791  19.703  8.551  1.00 33.50  ? 42  CYS L SG  1 
ATOM   19893 N N   . SER H 3 21  ? -5.654  21.616  5.382  1.00 29.55  ? 43  SER L N   1 
ATOM   19894 C CA  . SER H 3 21  ? -6.996  22.163  5.433  1.00 29.55  ? 43  SER L CA  1 
ATOM   19895 C C   . SER H 3 21  ? -7.938  21.045  5.799  1.00 29.55  ? 43  SER L C   1 
ATOM   19896 O O   . SER H 3 21  ? -7.870  19.962  5.233  1.00 29.55  ? 43  SER L O   1 
ATOM   19897 C CB  . SER H 3 21  ? -7.383  22.735  4.076  1.00 31.49  ? 43  SER L CB  1 
ATOM   19898 O OG  . SER H 3 21  ? -6.396  23.636  3.612  1.00 31.49  ? 43  SER L OG  1 
ATOM   19899 N N   . GLY H 3 22  ? -8.852  21.317  6.719  1.00 28.52  ? 44  GLY L N   1 
ATOM   19900 C CA  . GLY H 3 22  ? -9.801  20.307  7.130  1.00 28.52  ? 44  GLY L CA  1 
ATOM   19901 C C   . GLY H 3 22  ? -11.197 20.823  7.384  1.00 28.52  ? 44  GLY L C   1 
ATOM   19902 O O   . GLY H 3 22  ? -11.432 22.022  7.474  1.00 28.52  ? 44  GLY L O   1 
ATOM   19903 N N   . SER H 3 23  ? -12.126 19.886  7.498  1.00 28.39  ? 45  SER L N   1 
ATOM   19904 C CA  . SER H 3 23  ? -13.529 20.163  7.765  1.00 28.39  ? 45  SER L CA  1 
ATOM   19905 C C   . SER H 3 23  ? -13.770 20.442  9.240  1.00 28.39  ? 45  SER L C   1 
ATOM   19906 O O   . SER H 3 23  ? -12.886 20.271  10.068 1.00 28.39  ? 45  SER L O   1 
ATOM   19907 C CB  . SER H 3 23  ? -14.397 18.995  7.321  1.00 30.50  ? 45  SER L CB  1 
ATOM   19908 O OG  . SER H 3 23  ? -15.719 19.157  7.797  1.00 30.50  ? 45  SER L OG  1 
ATOM   19909 N N   . SER H 3 24  ? -14.982 20.869  9.567  1.00 29.31  ? 46  SER L N   1 
ATOM   19910 C CA  . SER H 3 24  ? -15.353 21.179  10.942 1.00 29.31  ? 46  SER L CA  1 
ATOM   19911 C C   . SER H 3 24  ? -15.240 19.970  11.856 1.00 29.31  ? 46  SER L C   1 
ATOM   19912 O O   . SER H 3 24  ? -14.834 20.095  13.007 1.00 29.31  ? 46  SER L O   1 
ATOM   19913 C CB  . SER H 3 24  ? -16.785 21.704  10.994 1.00 33.60  ? 46  SER L CB  1 
ATOM   19914 O OG  . SER H 3 24  ? -17.299 21.630  12.311 1.00 33.60  ? 46  SER L OG  1 
ATOM   19915 N N   . SER H 3 25  ? -15.618 18.805  11.340 1.00 26.03  ? 47  SER L N   1 
ATOM   19916 C CA  . SER H 3 25  ? -15.579 17.556  12.087 1.00 26.03  ? 47  SER L CA  1 
ATOM   19917 C C   . SER H 3 25  ? -14.185 17.133  12.543 1.00 26.03  ? 47  SER L C   1 
ATOM   19918 O O   . SER H 3 25  ? -14.045 16.587  13.625 1.00 26.03  ? 47  SER L O   1 
ATOM   19919 C CB  . SER H 3 25  ? -16.248 16.433  11.298 1.00 28.38  ? 47  SER L CB  1 
ATOM   19920 O OG  . SER H 3 25  ? -15.827 16.439  9.950  1.00 28.38  ? 47  SER L OG  1 
ATOM   19921 N N   . ASN H 3 26  ? -13.157 17.341  11.729 1.00 23.61  ? 48  ASN L N   1 
ATOM   19922 C CA  . ASN H 3 26  ? -11.820 16.946  12.172 1.00 23.61  ? 48  ASN L CA  1 
ATOM   19923 C C   . ASN H 3 26  ? -10.914 18.082  12.685 1.00 23.61  ? 48  ASN L C   1 
ATOM   19924 O O   . ASN H 3 26  ? -10.708 18.210  13.884 1.00 23.61  ? 48  ASN L O   1 
ATOM   19925 C CB  . ASN H 3 26  ? -11.105 16.065  11.130 1.00 24.16  ? 48  ASN L CB  1 
ATOM   19926 C CG  . ASN H 3 26  ? -11.226 16.598  9.722  1.00 24.16  ? 48  ASN L CG  1 
ATOM   19927 O OD1 . ASN H 3 26  ? -11.136 17.797  9.497  1.00 24.16  ? 48  ASN L OD1 1 
ATOM   19928 N ND2 . ASN H 3 26  ? -11.407 15.707  8.766  1.00 24.16  ? 48  ASN L ND2 1 
ATOM   19929 N N   . ILE H 3 27  ? -10.367 18.913  11.812 1.00 26.74  ? 49  ILE L N   1 
ATOM   19930 C CA  . ILE H 3 27  ? -9.491  19.965  12.290 1.00 26.74  ? 49  ILE L CA  1 
ATOM   19931 C C   . ILE H 3 27  ? -10.204 20.964  13.182 1.00 26.74  ? 49  ILE L C   1 
ATOM   19932 O O   . ILE H 3 27  ? -9.638  21.433  14.158 1.00 26.74  ? 49  ILE L O   1 
ATOM   19933 C CB  . ILE H 3 27  ? -8.810  20.722  11.141 1.00 27.68  ? 49  ILE L CB  1 
ATOM   19934 C CG1 . ILE H 3 27  ? -7.852  19.801  10.393 1.00 27.68  ? 49  ILE L CG1 1 
ATOM   19935 C CG2 . ILE H 3 27  ? -8.048  21.914  11.689 1.00 27.68  ? 49  ILE L CG2 1 
ATOM   19936 C CD1 . ILE H 3 27  ? -6.774  19.214  11.271 1.00 27.68  ? 49  ILE L CD1 1 
ATOM   19937 N N   . GLY H 3 28  ? -11.448 21.285  12.858 1.00 26.97  ? 50  GLY L N   1 
ATOM   19938 C CA  . GLY H 3 28  ? -12.186 22.264  13.632 1.00 26.97  ? 50  GLY L CA  1 
ATOM   19939 C C   . GLY H 3 28  ? -12.479 21.962  15.086 1.00 26.97  ? 50  GLY L C   1 
ATOM   19940 O O   . GLY H 3 28  ? -12.327 22.831  15.935 1.00 26.97  ? 50  GLY L O   1 
ATOM   19941 N N   . SER H 3 29  ? -12.895 20.740  15.389 1.00 26.32  ? 51  SER L N   1 
ATOM   19942 C CA  . SER H 3 29  ? -13.209 20.376  16.769 1.00 26.32  ? 51  SER L CA  1 
ATOM   19943 C C   . SER H 3 29  ? -12.255 19.401  17.459 1.00 26.32  ? 51  SER L C   1 
ATOM   19944 O O   . SER H 3 29  ? -12.521 18.976  18.576 1.00 26.32  ? 51  SER L O   1 
ATOM   19945 C CB  . SER H 3 29  ? -14.641 19.846  16.859 1.00 26.00  ? 51  SER L CB  1 
ATOM   19946 O OG  . SER H 3 29  ? -14.976 19.103  15.707 1.00 26.00  ? 51  SER L OG  1 
ATOM   19947 N N   . ASN H 3 30  ? -11.150 19.049  16.814 1.00 22.79  ? 52  ASN L N   1 
ATOM   19948 C CA  . ASN H 3 30  ? -10.222 18.093  17.401 1.00 22.79  ? 52  ASN L CA  1 
ATOM   19949 C C   . ASN H 3 30  ? -8.764  18.513  17.311 1.00 22.79  ? 52  ASN L C   1 
ATOM   19950 O O   . ASN H 3 30  ? -8.392  19.303  16.456 1.00 22.79  ? 52  ASN L O   1 
ATOM   19951 C CB  . ASN H 3 30  ? -10.388 16.737  16.724 1.00 19.76  ? 52  ASN L CB  1 
ATOM   19952 C CG  . ASN H 3 30  ? -11.704 16.075  17.053 1.00 19.76  ? 52  ASN L CG  1 
ATOM   19953 O OD1 . ASN H 3 30  ? -12.537 15.866  16.184 1.00 19.76  ? 52  ASN L OD1 1 
ATOM   19954 N ND2 . ASN H 3 30  ? -11.898 15.747  18.317 1.00 19.76  ? 52  ASN L ND2 1 
ATOM   19955 N N   . TYR H 3 31  ? -7.941  17.975  18.205 1.00 22.17  ? 53  TYR L N   1 
ATOM   19956 C CA  . TYR H 3 31  ? -6.514  18.263  18.215 1.00 22.17  ? 53  TYR L CA  1 
ATOM   19957 C C   . TYR H 3 31  ? -5.866  17.714  16.957 1.00 22.17  ? 53  TYR L C   1 
ATOM   19958 O O   . TYR H 3 31  ? -6.269  16.670  16.457 1.00 22.17  ? 53  TYR L O   1 
ATOM   19959 C CB  . TYR H 3 31  ? -5.838  17.624  19.425 1.00 23.54  ? 53  TYR L CB  1 
ATOM   19960 C CG  . TYR H 3 31  ? -6.129  18.304  20.732 1.00 23.54  ? 53  TYR L CG  1 
ATOM   19961 C CD1 . TYR H 3 31  ? -5.702  19.597  20.970 1.00 23.54  ? 53  TYR L CD1 1 
ATOM   19962 C CD2 . TYR H 3 31  ? -6.818  17.647  21.734 1.00 23.54  ? 53  TYR L CD2 1 
ATOM   19963 C CE1 . TYR H 3 31  ? -5.967  20.224  22.168 1.00 23.54  ? 53  TYR L CE1 1 
ATOM   19964 C CE2 . TYR H 3 31  ? -7.087  18.264  22.935 1.00 23.54  ? 53  TYR L CE2 1 
ATOM   19965 C CZ  . TYR H 3 31  ? -6.658  19.550  23.145 1.00 23.54  ? 53  TYR L CZ  1 
ATOM   19966 O OH  . TYR H 3 31  ? -6.922  20.167  24.341 1.00 23.54  ? 53  TYR L OH  1 
ATOM   19967 N N   . VAL H 3 32  ? -4.850  18.411  16.462 1.00 19.34  ? 54  VAL L N   1 
ATOM   19968 C CA  . VAL H 3 32  ? -4.143  17.997  15.258 1.00 19.34  ? 54  VAL L CA  1 
ATOM   19969 C C   . VAL H 3 32  ? -2.721  17.548  15.591 1.00 19.34  ? 54  VAL L C   1 
ATOM   19970 O O   . VAL H 3 32  ? -2.014  18.218  16.331 1.00 19.34  ? 54  VAL L O   1 
ATOM   19971 C CB  . VAL H 3 32  ? -4.138  19.123  14.206 1.00 20.41  ? 54  VAL L CB  1 
ATOM   19972 C CG1 . VAL H 3 32  ? -3.763  20.445  14.845 1.00 20.41  ? 54  VAL L CG1 1 
ATOM   19973 C CG2 . VAL H 3 32  ? -3.214  18.796  13.048 1.00 20.41  ? 54  VAL L CG2 1 
ATOM   19974 N N   . TYR H 3 33  ? -2.320  16.403  15.051 1.00 16.91  ? 55  TYR L N   1 
ATOM   19975 C CA  . TYR H 3 33  ? -1.003  15.834  15.290 1.00 16.91  ? 55  TYR L CA  1 
ATOM   19976 C C   . TYR H 3 33  ? -0.170  15.886  14.031 1.00 16.91  ? 55  TYR L C   1 
ATOM   19977 O O   . TYR H 3 33  ? -0.701  15.824  12.935 1.00 16.91  ? 55  TYR L O   1 
ATOM   19978 C CB  . TYR H 3 33  ? -1.127  14.371  15.695 1.00 17.07  ? 55  TYR L CB  1 
ATOM   19979 C CG  . TYR H 3 33  ? -1.723  14.121  17.052 1.00 17.07  ? 55  TYR L CG  1 
ATOM   19980 C CD1 . TYR H 3 33  ? -2.970  14.612  17.383 1.00 17.07  ? 55  TYR L CD1 1 
ATOM   19981 C CD2 . TYR H 3 33  ? -1.047  13.364  17.992 1.00 17.07  ? 55  TYR L CD2 1 
ATOM   19982 C CE1 . TYR H 3 33  ? -3.518  14.380  18.621 1.00 17.07  ? 55  TYR L CE1 1 
ATOM   19983 C CE2 . TYR H 3 33  ? -1.589  13.124  19.231 1.00 17.07  ? 55  TYR L CE2 1 
ATOM   19984 C CZ  . TYR H 3 33  ? -2.824  13.637  19.538 1.00 17.07  ? 55  TYR L CZ  1 
ATOM   19985 O OH  . TYR H 3 33  ? -3.368  13.399  20.773 1.00 17.07  ? 55  TYR L OH  1 
ATOM   19986 N N   . TRP H 3 34  ? 1.140   16.017  14.193 1.00 16.66  ? 56  TRP L N   1 
ATOM   19987 C CA  . TRP H 3 34  ? 2.060   16.051  13.065 1.00 16.66  ? 56  TRP L CA  1 
ATOM   19988 C C   . TRP H 3 34  ? 3.061   14.910  13.139 1.00 16.66  ? 56  TRP L C   1 
ATOM   19989 O O   . TRP H 3 34  ? 3.704   14.717  14.153 1.00 16.66  ? 56  TRP L O   1 
ATOM   19990 C CB  . TRP H 3 34  ? 2.784   17.384  13.014 1.00 19.26  ? 56  TRP L CB  1 
ATOM   19991 C CG  . TRP H 3 34  ? 1.933   18.448  12.478 1.00 19.26  ? 56  TRP L CG  1 
ATOM   19992 C CD1 . TRP H 3 34  ? 1.209   19.350  13.186 1.00 19.26  ? 56  TRP L CD1 1 
ATOM   19993 C CD2 . TRP H 3 34  ? 1.690   18.724  11.102 1.00 19.26  ? 56  TRP L CD2 1 
ATOM   19994 N NE1 . TRP H 3 34  ? 0.533   20.182  12.336 1.00 19.26  ? 56  TRP L NE1 1 
ATOM   19995 C CE2 . TRP H 3 34  ? 0.812   19.816  11.047 1.00 19.26  ? 56  TRP L CE2 1 
ATOM   19996 C CE3 . TRP H 3 34  ? 2.137   18.158  9.908  1.00 19.26  ? 56  TRP L CE3 1 
ATOM   19997 C CZ2 . TRP H 3 34  ? 0.370   20.352  9.850  1.00 19.26  ? 56  TRP L CZ2 1 
ATOM   19998 C CZ3 . TRP H 3 34  ? 1.698   18.688  8.726  1.00 19.26  ? 56  TRP L CZ3 1 
ATOM   19999 C CH2 . TRP H 3 34  ? 0.823   19.774  8.701  1.00 19.26  ? 56  TRP L CH2 1 
ATOM   20000 N N   . TYR H 3 35  ? 3.189   14.155  12.059 1.00 17.65  ? 57  TYR L N   1 
ATOM   20001 C CA  . TYR H 3 35  ? 4.110   13.036  12.027 1.00 17.65  ? 57  TYR L CA  1 
ATOM   20002 C C   . TYR H 3 35  ? 5.146   13.227  10.950 1.00 17.65  ? 57  TYR L C   1 
ATOM   20003 O O   . TYR H 3 35  ? 4.818   13.606  9.842  1.00 17.65  ? 57  TYR L O   1 
ATOM   20004 C CB  . TYR H 3 35  ? 3.352   11.735  11.787 1.00 16.28  ? 57  TYR L CB  1 
ATOM   20005 C CG  . TYR H 3 35  ? 2.400   11.427  12.901 1.00 16.28  ? 57  TYR L CG  1 
ATOM   20006 C CD1 . TYR H 3 35  ? 2.862   10.930  14.099 1.00 16.28  ? 57  TYR L CD1 1 
ATOM   20007 C CD2 . TYR H 3 35  ? 1.045   11.670  12.771 1.00 16.28  ? 57  TYR L CD2 1 
ATOM   20008 C CE1 . TYR H 3 35  ? 2.003   10.666  15.132 1.00 16.28  ? 57  TYR L CE1 1 
ATOM   20009 C CE2 . TYR H 3 35  ? 0.180   11.409  13.803 1.00 16.28  ? 57  TYR L CE2 1 
ATOM   20010 C CZ  . TYR H 3 35  ? 0.675   10.912  14.978 1.00 16.28  ? 57  TYR L CZ  1 
ATOM   20011 O OH  . TYR H 3 35  ? -0.165  10.645  16.015 1.00 16.28  ? 57  TYR L OH  1 
ATOM   20012 N N   . GLN H 3 36  ? 6.406   12.988  11.279 1.00 21.81  ? 58  GLN L N   1 
ATOM   20013 C CA  . GLN H 3 36  ? 7.460   13.112  10.288 1.00 21.81  ? 58  GLN L CA  1 
ATOM   20014 C C   . GLN H 3 36  ? 7.942   11.721  9.946  1.00 21.81  ? 58  GLN L C   1 
ATOM   20015 O O   . GLN H 3 36  ? 8.346   10.967  10.817 1.00 21.81  ? 58  GLN L O   1 
ATOM   20016 C CB  . GLN H 3 36  ? 8.628   13.937  10.816 1.00 27.81  ? 58  GLN L CB  1 
ATOM   20017 C CG  . GLN H 3 36  ? 9.751   14.085  9.808  1.00 27.81  ? 58  GLN L CG  1 
ATOM   20018 C CD  . GLN H 3 36  ? 11.003  14.690  10.402 1.00 27.81  ? 58  GLN L CD  1 
ATOM   20019 O OE1 . GLN H 3 36  ? 11.201  14.672  11.611 1.00 27.81  ? 58  GLN L OE1 1 
ATOM   20020 N NE2 . GLN H 3 36  ? 11.860  15.221  9.549  1.00 27.81  ? 58  GLN L NE2 1 
ATOM   20021 N N   . GLN H 3 37  ? 7.893   11.380  8.669  1.00 24.26  ? 59  GLN L N   1 
ATOM   20022 C CA  . GLN H 3 37  ? 8.335   10.074  8.241  1.00 24.26  ? 59  GLN L CA  1 
ATOM   20023 C C   . GLN H 3 37  ? 9.346   10.170  7.126  1.00 24.26  ? 59  GLN L C   1 
ATOM   20024 O O   . GLN H 3 37  ? 9.200   10.958  6.205  1.00 24.26  ? 59  GLN L O   1 
ATOM   20025 C CB  . GLN H 3 37  ? 7.158   9.244   7.754  1.00 24.47  ? 59  GLN L CB  1 
ATOM   20026 C CG  . GLN H 3 37  ? 7.525   7.805   7.464  1.00 24.47  ? 59  GLN L CG  1 
ATOM   20027 C CD  . GLN H 3 37  ? 6.666   7.197   6.389  1.00 24.47  ? 59  GLN L CD  1 
ATOM   20028 O OE1 . GLN H 3 37  ? 6.223   7.886   5.476  1.00 24.47  ? 59  GLN L OE1 1 
ATOM   20029 N NE2 . GLN H 3 37  ? 6.434   5.897   6.483  1.00 24.47  ? 59  GLN L NE2 1 
ATOM   20030 N N   . ILE H 3 38  ? 10.375  9.346   7.221  1.00 27.86  ? 60  ILE L N   1 
ATOM   20031 C CA  . ILE H 3 38  ? 11.417  9.265   6.217  1.00 27.86  ? 60  ILE L CA  1 
ATOM   20032 C C   . ILE H 3 38  ? 11.185  7.891   5.620  1.00 27.86  ? 60  ILE L C   1 
ATOM   20033 O O   . ILE H 3 38  ? 10.998  6.933   6.358  1.00 27.86  ? 60  ILE L O   1 
ATOM   20034 C CB  . ILE H 3 38  ? 12.807  9.387   6.847  1.00 26.64  ? 60  ILE L CB  1 
ATOM   20035 C CG1 . ILE H 3 38  ? 12.918  10.729  7.570  1.00 26.64  ? 60  ILE L CG1 1 
ATOM   20036 C CG2 . ILE H 3 38  ? 13.881  9.272   5.783  1.00 26.64  ? 60  ILE L CG2 1 
ATOM   20037 C CD1 . ILE H 3 38  ? 14.183  10.902  8.370  1.00 26.64  ? 60  ILE L CD1 1 
ATOM   20038 N N   . PRO H 3 39  ? 11.212  7.776   4.286  1.00 32.74  ? 61  PRO L N   1 
ATOM   20039 C CA  . PRO H 3 39  ? 10.882  6.488   3.665  1.00 32.74  ? 61  PRO L CA  1 
ATOM   20040 C C   . PRO H 3 39  ? 11.725  5.314   4.151  1.00 32.74  ? 61  PRO L C   1 
ATOM   20041 O O   . PRO H 3 39  ? 12.933  5.430   4.346  1.00 32.74  ? 61  PRO L O   1 
ATOM   20042 C CB  . PRO H 3 39  ? 11.134  6.755   2.185  1.00 31.50  ? 61  PRO L CB  1 
ATOM   20043 C CG  . PRO H 3 39  ? 10.836  8.208   2.033  1.00 31.50  ? 61  PRO L CG  1 
ATOM   20044 C CD  . PRO H 3 39  ? 11.349  8.850   3.290  1.00 31.50  ? 61  PRO L CD  1 
ATOM   20045 N N   . GLY H 3 40  ? 11.048  4.186   4.362  1.00 33.12  ? 62  GLY L N   1 
ATOM   20046 C CA  . GLY H 3 40  ? 11.670  2.981   4.873  1.00 33.12  ? 62  GLY L CA  1 
ATOM   20047 C C   . GLY H 3 40  ? 11.752  2.977   6.391  1.00 33.12  ? 62  GLY L C   1 
ATOM   20048 O O   . GLY H 3 40  ? 12.405  2.123   6.980  1.00 33.12  ? 62  GLY L O   1 
ATOM   20049 N N   . THR H 3 41  ? 11.097  3.943   7.025  1.00 25.94  ? 63  THR L N   1 
ATOM   20050 C CA  . THR H 3 41  ? 11.112  4.064   8.476  1.00 25.94  ? 63  THR L CA  1 
ATOM   20051 C C   . THR H 3 41  ? 9.708   4.304   9.017  1.00 25.94  ? 63  THR L C   1 
ATOM   20052 O O   . THR H 3 41  ? 8.845   4.812   8.313  1.00 25.94  ? 63  THR L O   1 
ATOM   20053 C CB  . THR H 3 41  ? 11.992  5.257   8.916  1.00 27.92  ? 63  THR L CB  1 
ATOM   20054 O OG1 . THR H 3 41  ? 13.114  5.385   8.036  1.00 27.92  ? 63  THR L OG1 1 
ATOM   20055 C CG2 . THR H 3 41  ? 12.490  5.095   10.342 1.00 27.92  ? 63  THR L CG2 1 
ATOM   20056 N N   . ALA H 3 42  ? 9.475   3.896   10.258 1.00 21.21  ? 64  ALA L N   1 
ATOM   20057 C CA  . ALA H 3 42  ? 8.205   4.129   10.916 1.00 21.21  ? 64  ALA L CA  1 
ATOM   20058 C C   . ALA H 3 42  ? 8.140   5.615   11.229 1.00 21.21  ? 64  ALA L C   1 
ATOM   20059 O O   . ALA H 3 42  ? 9.157   6.221   11.541 1.00 21.21  ? 64  ALA L O   1 
ATOM   20060 C CB  . ALA H 3 42  ? 8.124   3.319   12.193 1.00 18.30  ? 64  ALA L CB  1 
ATOM   20061 N N   . PRO H 3 43  ? 6.943   6.213   11.171 1.00 17.04  ? 65  PRO L N   1 
ATOM   20062 C CA  . PRO H 3 43  ? 6.786   7.647   11.450 1.00 17.04  ? 65  PRO L CA  1 
ATOM   20063 C C   . PRO H 3 43  ? 7.194   8.104   12.856 1.00 17.04  ? 65  PRO L C   1 
ATOM   20064 O O   . PRO H 3 43  ? 7.246   7.323   13.797 1.00 17.04  ? 65  PRO L O   1 
ATOM   20065 C CB  . PRO H 3 43  ? 5.293   7.875   11.237 1.00 16.57  ? 65  PRO L CB  1 
ATOM   20066 C CG  . PRO H 3 43  ? 4.887   6.808   10.283 1.00 16.57  ? 65  PRO L CG  1 
ATOM   20067 C CD  . PRO H 3 43  ? 5.705   5.612   10.655 1.00 16.57  ? 65  PRO L CD  1 
ATOM   20068 N N   . LYS H 3 44  ? 7.481   9.392   12.985 1.00 19.03  ? 66  LYS L N   1 
ATOM   20069 C CA  . LYS H 3 44  ? 7.871   9.972   14.262 1.00 19.03  ? 66  LYS L CA  1 
ATOM   20070 C C   . LYS H 3 44  ? 6.949   11.136  14.621 1.00 19.03  ? 66  LYS L C   1 
ATOM   20071 O O   . LYS H 3 44  ? 6.582   11.916  13.757 1.00 19.03  ? 66  LYS L O   1 
ATOM   20072 C CB  . LYS H 3 44  ? 9.319   10.448  14.171 1.00 22.80  ? 66  LYS L CB  1 
ATOM   20073 C CG  . LYS H 3 44  ? 9.760   11.370  15.290 1.00 22.80  ? 66  LYS L CG  1 
ATOM   20074 C CD  . LYS H 3 44  ? 11.056  12.074  14.936 1.00 22.80  ? 66  LYS L CD  1 
ATOM   20075 C CE  . LYS H 3 44  ? 11.459  13.056  16.020 1.00 22.80  ? 66  LYS L CE  1 
ATOM   20076 N NZ  . LYS H 3 44  ? 12.733  13.749  15.689 1.00 22.80  ? 66  LYS L NZ  1 
ATOM   20077 N N   . LEU H 3 45  ? 6.567   11.261  15.886 1.00 18.60  ? 67  LEU L N   1 
ATOM   20078 C CA  . LEU H 3 45  ? 5.672   12.345  16.286 1.00 18.60  ? 67  LEU L CA  1 
ATOM   20079 C C   . LEU H 3 45  ? 6.402   13.669  16.523 1.00 18.60  ? 67  LEU L C   1 
ATOM   20080 O O   . LEU H 3 45  ? 7.322   13.747  17.325 1.00 18.60  ? 67  LEU L O   1 
ATOM   20081 C CB  . LEU H 3 45  ? 4.903   11.946  17.547 1.00 17.54  ? 67  LEU L CB  1 
ATOM   20082 C CG  . LEU H 3 45  ? 3.983   12.990  18.173 1.00 17.54  ? 67  LEU L CG  1 
ATOM   20083 C CD1 . LEU H 3 45  ? 2.718   13.132  17.357 1.00 17.54  ? 67  LEU L CD1 1 
ATOM   20084 C CD2 . LEU H 3 45  ? 3.642   12.614  19.599 1.00 17.54  ? 67  LEU L CD2 1 
ATOM   20085 N N   . LEU H 3 46  ? 5.982   14.710  15.814 1.00 20.64  ? 68  LEU L N   1 
ATOM   20086 C CA  . LEU H 3 46  ? 6.588   16.024  15.955 1.00 20.64  ? 68  LEU L CA  1 
ATOM   20087 C C   . LEU H 3 46  ? 5.774   16.971  16.808 1.00 20.64  ? 68  LEU L C   1 
ATOM   20088 O O   . LEU H 3 46  ? 6.309   17.645  17.673 1.00 20.64  ? 68  LEU L O   1 
ATOM   20089 C CB  . LEU H 3 46  ? 6.762   16.677  14.592 1.00 21.39  ? 68  LEU L CB  1 
ATOM   20090 C CG  . LEU H 3 46  ? 7.640   15.971  13.580 1.00 21.39  ? 68  LEU L CG  1 
ATOM   20091 C CD1 . LEU H 3 46  ? 7.729   16.838  12.342 1.00 21.39  ? 68  LEU L CD1 1 
ATOM   20092 C CD2 . LEU H 3 46  ? 9.013   15.743  14.177 1.00 21.39  ? 68  LEU L CD2 1 
ATOM   20093 N N   . ILE H 3 47  ? 4.479   17.041  16.536 1.00 19.65  ? 69  ILE L N   1 
ATOM   20094 C CA  . ILE H 3 47  ? 3.588   17.930  17.260 1.00 19.65  ? 69  ILE L CA  1 
ATOM   20095 C C   . ILE H 3 47  ? 2.283   17.223  17.578 1.00 19.65  ? 69  ILE L C   1 
ATOM   20096 O O   . ILE H 3 47  ? 1.684   16.606  16.713 1.00 19.65  ? 69  ILE L O   1 
ATOM   20097 C CB  . ILE H 3 47  ? 3.278   19.189  16.422 1.00 21.92  ? 69  ILE L CB  1 
ATOM   20098 C CG1 . ILE H 3 47  ? 4.510   20.081  16.292 1.00 21.92  ? 69  ILE L CG1 1 
ATOM   20099 C CG2 . ILE H 3 47  ? 2.147   19.996  17.030 1.00 21.92  ? 69  ILE L CG2 1 
ATOM   20100 C CD1 . ILE H 3 47  ? 4.912   20.747  17.583 1.00 21.92  ? 69  ILE L CD1 1 
ATOM   20101 N N   . TYR H 3 48  ? 1.852   17.311  18.828 1.00 20.78  ? 70  TYR L N   1 
ATOM   20102 C CA  . TYR H 3 48  ? 0.601   16.713  19.276 1.00 20.78  ? 70  TYR L CA  1 
ATOM   20103 C C   . TYR H 3 48  ? -0.186  17.777  20.028 1.00 20.78  ? 70  TYR L C   1 
ATOM   20104 O O   . TYR H 3 48  ? 0.386   18.771  20.450 1.00 20.78  ? 70  TYR L O   1 
ATOM   20105 C CB  . TYR H 3 48  ? 0.861   15.516  20.184 1.00 20.37  ? 70  TYR L CB  1 
ATOM   20106 C CG  . TYR H 3 48  ? 1.423   15.887  21.521 1.00 20.37  ? 70  TYR L CG  1 
ATOM   20107 C CD1 . TYR H 3 48  ? 0.594   16.248  22.564 1.00 20.37  ? 70  TYR L CD1 1 
ATOM   20108 C CD2 . TYR H 3 48  ? 2.786   15.886  21.742 1.00 20.37  ? 70  TYR L CD2 1 
ATOM   20109 C CE1 . TYR H 3 48  ? 1.108   16.600  23.793 1.00 20.37  ? 70  TYR L CE1 1 
ATOM   20110 C CE2 . TYR H 3 48  ? 3.310   16.235  22.967 1.00 20.37  ? 70  TYR L CE2 1 
ATOM   20111 C CZ  . TYR H 3 48  ? 2.466   16.591  23.986 1.00 20.37  ? 70  TYR L CZ  1 
ATOM   20112 O OH  . TYR H 3 48  ? 2.986   16.938  25.204 1.00 20.37  ? 70  TYR L OH  1 
ATOM   20113 N N   . SER H 3 49  ? -1.498  17.609  20.144 1.00 23.21  ? 71  SER L N   1 
ATOM   20114 C CA  . SER H 3 49  ? -2.333  18.572  20.864 1.00 23.21  ? 71  SER L CA  1 
ATOM   20115 C C   . SER H 3 49  ? -2.164  20.010  20.373 1.00 23.21  ? 71  SER L C   1 
ATOM   20116 O O   . SER H 3 49  ? -1.955  20.923  21.169 1.00 23.21  ? 71  SER L O   1 
ATOM   20117 C CB  . SER H 3 49  ? -2.154  18.473  22.386 1.00 26.83  ? 71  SER L CB  1 
ATOM   20118 O OG  . SER H 3 49  ? -2.474  17.177  22.857 1.00 26.83  ? 71  SER L OG  1 
ATOM   20119 N N   . ASN H 3 50  ? -2.177  20.150  19.049 1.00 23.40  ? 72  ASN L N   1 
ATOM   20120 C CA  . ASN H 3 50  ? -2.075  21.403  18.283 1.00 23.40  ? 72  ASN L CA  1 
ATOM   20121 C C   . ASN H 3 50  ? -0.729  22.109  18.275 1.00 23.40  ? 72  ASN L C   1 
ATOM   20122 O O   . ASN H 3 50  ? -0.136  22.267  17.224 1.00 23.40  ? 72  ASN L O   1 
ATOM   20123 C CB  . ASN H 3 50  ? -3.200  22.399  18.613 1.00 23.82  ? 72  ASN L CB  1 
ATOM   20124 C CG  . ASN H 3 50  ? -4.561  21.879  18.241 1.00 23.82  ? 72  ASN L CG  1 
ATOM   20125 O OD1 . ASN H 3 50  ? -4.689  21.045  17.357 1.00 23.82  ? 72  ASN L OD1 1 
ATOM   20126 N ND2 . ASN H 3 50  ? -5.586  22.368  18.914 1.00 23.82  ? 72  ASN L ND2 1 
ATOM   20127 N N   . ASN H 3 51  ? -0.240  22.538  19.429 1.00 24.68  ? 73  ASN L N   1 
ATOM   20128 C CA  . ASN H 3 51  ? 1.041   23.228  19.463 1.00 24.68  ? 73  ASN L CA  1 
ATOM   20129 C C   . ASN H 3 51  ? 2.103   22.567  20.322 1.00 24.68  ? 73  ASN L C   1 
ATOM   20130 O O   . ASN H 3 51  ? 3.254   22.979  20.307 1.00 24.68  ? 73  ASN L O   1 
ATOM   20131 C CB  . ASN H 3 51  ? 0.840   24.664  19.920 1.00 27.67  ? 73  ASN L CB  1 
ATOM   20132 C CG  . ASN H 3 51  ? -0.133  24.772  21.068 1.00 27.67  ? 73  ASN L CG  1 
ATOM   20133 O OD1 . ASN H 3 51  ? 0.011   24.099  22.082 1.00 27.67  ? 73  ASN L OD1 1 
ATOM   20134 N ND2 . ASN H 3 51  ? -1.133  25.622  20.915 1.00 27.67  ? 73  ASN L ND2 1 
ATOM   20135 N N   . GLN H 3 52  ? 1.714   21.554  21.080 1.00 23.50  ? 74  GLN L N   1 
ATOM   20136 C CA  . GLN H 3 52  ? 2.637   20.856  21.960 1.00 23.50  ? 74  GLN L CA  1 
ATOM   20137 C C   . GLN H 3 52  ? 3.582   19.955  21.199 1.00 23.50  ? 74  GLN L C   1 
ATOM   20138 O O   . GLN H 3 52  ? 3.297   19.541  20.093 1.00 23.50  ? 74  GLN L O   1 
ATOM   20139 C CB  . GLN H 3 52  ? 1.868   20.055  23.004 1.00 25.19  ? 74  GLN L CB  1 
ATOM   20140 C CG  . GLN H 3 52  ? 1.001   20.908  23.908 1.00 25.19  ? 74  GLN L CG  1 
ATOM   20141 C CD  . GLN H 3 52  ? 1.821   21.792  24.822 1.00 25.19  ? 74  GLN L CD  1 
ATOM   20142 O OE1 . GLN H 3 52  ? 2.546   21.308  25.687 1.00 25.19  ? 74  GLN L OE1 1 
ATOM   20143 N NE2 . GLN H 3 52  ? 1.704   23.098  24.638 1.00 25.19  ? 74  GLN L NE2 1 
ATOM   20144 N N   . ARG H 3 53  ? 4.735   19.675  21.775 1.00 27.87  ? 75  ARG L N   1 
ATOM   20145 C CA  . ARG H 3 53  ? 5.668   18.785  21.114 1.00 27.87  ? 75  ARG L CA  1 
ATOM   20146 C C   . ARG H 3 53  ? 6.363   17.885  22.113 1.00 27.87  ? 75  ARG L C   1 
ATOM   20147 O O   . ARG H 3 53  ? 6.659   18.294  23.227 1.00 27.87  ? 75  ARG L O   1 
ATOM   20148 C CB  . ARG H 3 53  ? 6.664   19.547  20.240 1.00 33.18  ? 75  ARG L CB  1 
ATOM   20149 C CG  . ARG H 3 53  ? 7.580   20.502  20.959 1.00 33.18  ? 75  ARG L CG  1 
ATOM   20150 C CD  . ARG H 3 53  ? 8.441   21.241  19.955 1.00 33.18  ? 75  ARG L CD  1 
ATOM   20151 N NE  . ARG H 3 53  ? 9.497   21.969  20.633 1.00 33.18  ? 75  ARG L NE  1 
ATOM   20152 C CZ  . ARG H 3 53  ? 9.294   23.080  21.326 1.00 33.18  ? 75  ARG L CZ  1 
ATOM   20153 N NH1 . ARG H 3 53  ? 8.074   23.586  21.418 1.00 33.18  ? 75  ARG L NH1 1 
ATOM   20154 N NH2 . ARG H 3 53  ? 10.309  23.682  21.926 1.00 33.18  ? 75  ARG L NH2 1 
ATOM   20155 N N   . PRO H 3 54  ? 6.623   16.641  21.705 1.00 26.72  ? 76  PRO L N   1 
ATOM   20156 C CA  . PRO H 3 54  ? 7.263   15.641  22.558 1.00 26.72  ? 76  PRO L CA  1 
ATOM   20157 C C   . PRO H 3 54  ? 8.719   15.934  22.815 1.00 26.72  ? 76  PRO L C   1 
ATOM   20158 O O   . PRO H 3 54  ? 9.336   16.668  22.057 1.00 26.72  ? 76  PRO L O   1 
ATOM   20159 C CB  . PRO H 3 54  ? 7.142   14.363  21.736 1.00 24.86  ? 76  PRO L CB  1 
ATOM   20160 C CG  . PRO H 3 54  ? 7.145   14.835  20.332 1.00 24.86  ? 76  PRO L CG  1 
ATOM   20161 C CD  . PRO H 3 54  ? 6.398   16.132  20.342 1.00 24.86  ? 76  PRO L CD  1 
ATOM   20162 N N   . SER H 3 55  ? 9.253   15.376  23.894 1.00 28.19  ? 77  SER L N   1 
ATOM   20163 C CA  . SER H 3 55  ? 10.657  15.544  24.233 1.00 28.19  ? 77  SER L CA  1 
ATOM   20164 C C   . SER H 3 55  ? 11.495  14.812  23.200 1.00 28.19  ? 77  SER L C   1 
ATOM   20165 O O   . SER H 3 55  ? 11.090  13.770  22.687 1.00 28.19  ? 77  SER L O   1 
ATOM   20166 C CB  . SER H 3 55  ? 10.948  14.969  25.612 1.00 27.61  ? 77  SER L CB  1 
ATOM   20167 O OG  . SER H 3 55  ? 11.021  13.557  25.553 1.00 27.61  ? 77  SER L OG  1 
ATOM   20168 N N   . GLY H 3 56  ? 12.686  15.329  22.927 1.00 33.68  ? 78  GLY L N   1 
ATOM   20169 C CA  . GLY H 3 56  ? 13.550  14.724  21.931 1.00 33.68  ? 78  GLY L CA  1 
ATOM   20170 C C   . GLY H 3 56  ? 13.304  15.289  20.550 1.00 33.68  ? 78  GLY L C   1 
ATOM   20171 O O   . GLY H 3 56  ? 13.849  14.806  19.561 1.00 33.68  ? 78  GLY L O   1 
ATOM   20172 N N   . VAL H 3 57  ? 12.468  16.316  20.492 1.00 32.20  ? 79  VAL L N   1 
ATOM   20173 C CA  . VAL H 3 57  ? 12.141  17.002  19.254 1.00 32.20  ? 79  VAL L CA  1 
ATOM   20174 C C   . VAL H 3 57  ? 12.693  18.409  19.398 1.00 32.20  ? 79  VAL L C   1 
ATOM   20175 O O   . VAL H 3 57  ? 12.502  19.042  20.430 1.00 32.20  ? 79  VAL L O   1 
ATOM   20176 C CB  . VAL H 3 57  ? 10.622  17.031  18.993 1.00 26.99  ? 79  VAL L CB  1 
ATOM   20177 C CG1 . VAL H 3 57  ? 10.278  18.056  17.928 1.00 26.99  ? 79  VAL L CG1 1 
ATOM   20178 C CG2 . VAL H 3 57  ? 10.141  15.656  18.568 1.00 26.99  ? 79  VAL L CG2 1 
ATOM   20179 N N   . PRO H 3 58  ? 13.384  18.899  18.362 1.00 35.56  ? 80  PRO L N   1 
ATOM   20180 C CA  . PRO H 3 58  ? 14.014  20.219  18.349 1.00 35.56  ? 80  PRO L CA  1 
ATOM   20181 C C   . PRO H 3 58  ? 13.008  21.343  18.455 1.00 35.56  ? 80  PRO L C   1 
ATOM   20182 O O   . PRO H 3 58  ? 11.862  21.212  18.049 1.00 35.56  ? 80  PRO L O   1 
ATOM   20183 C CB  . PRO H 3 58  ? 14.693  20.269  16.983 1.00 34.81  ? 80  PRO L CB  1 
ATOM   20184 C CG  . PRO H 3 58  ? 14.903  18.847  16.614 1.00 34.81  ? 80  PRO L CG  1 
ATOM   20185 C CD  . PRO H 3 58  ? 13.704  18.131  17.150 1.00 34.81  ? 80  PRO L CD  1 
ATOM   20186 N N   . ASP H 3 59  ? 13.467  22.449  19.016 1.00 35.24  ? 81  ASP L N   1 
ATOM   20187 C CA  . ASP H 3 59  ? 12.668  23.645  19.242 1.00 35.24  ? 81  ASP L CA  1 
ATOM   20188 C C   . ASP H 3 59  ? 12.125  24.305  17.974 1.00 35.24  ? 81  ASP L C   1 
ATOM   20189 O O   . ASP H 3 59  ? 11.083  24.954  18.014 1.00 35.24  ? 81  ASP L O   1 
ATOM   20190 C CB  . ASP H 3 59  ? 13.484  24.657  20.042 1.00 44.22  ? 81  ASP L CB  1 
ATOM   20191 C CG  . ASP H 3 59  ? 12.647  25.798  20.560 1.00 44.22  ? 81  ASP L CG  1 
ATOM   20192 O OD1 . ASP H 3 59  ? 11.408  25.736  20.421 1.00 44.22  ? 81  ASP L OD1 1 
ATOM   20193 O OD2 . ASP H 3 59  ? 13.232  26.754  21.110 1.00 44.22  ? 81  ASP L OD2 1 
ATOM   20194 N N   . ARG H 3 60  ? 12.835  24.165  16.859 1.00 34.53  ? 82  ARG L N   1 
ATOM   20195 C CA  . ARG H 3 60  ? 12.410  24.799  15.613 1.00 34.53  ? 82  ARG L CA  1 
ATOM   20196 C C   . ARG H 3 60  ? 11.040  24.356  15.096 1.00 34.53  ? 82  ARG L C   1 
ATOM   20197 O O   . ARG H 3 60  ? 10.285  25.182  14.600 1.00 34.53  ? 82  ARG L O   1 
ATOM   20198 C CB  . ARG H 3 60  ? 13.475  24.651  14.522 1.00 36.11  ? 82  ARG L CB  1 
ATOM   20199 C CG  . ARG H 3 60  ? 13.807  23.225  14.118 1.00 36.11  ? 82  ARG L CG  1 
ATOM   20200 C CD  . ARG H 3 60  ? 14.878  23.225  13.040 1.00 36.11  ? 82  ARG L CD  1 
ATOM   20201 N NE  . ARG H 3 60  ? 15.305  21.884  12.661 1.00 36.11  ? 82  ARG L NE  1 
ATOM   20202 C CZ  . ARG H 3 60  ? 16.170  21.160  13.358 1.00 36.11  ? 82  ARG L CZ  1 
ATOM   20203 N NH1 . ARG H 3 60  ? 16.685  21.645  14.476 1.00 36.11  ? 82  ARG L NH1 1 
ATOM   20204 N NH2 . ARG H 3 60  ? 16.513  19.949  12.946 1.00 36.11  ? 82  ARG L NH2 1 
ATOM   20205 N N   . PHE H 3 61  ? 10.693  23.083  15.251 1.00 32.99  ? 83  PHE L N   1 
ATOM   20206 C CA  . PHE H 3 61  ? 9.389   22.586  14.808 1.00 32.99  ? 83  PHE L CA  1 
ATOM   20207 C C   . PHE H 3 61  ? 8.246   23.175  15.625 1.00 32.99  ? 83  PHE L C   1 
ATOM   20208 O O   . PHE H 3 61  ? 8.092   22.850  16.792 1.00 32.99  ? 83  PHE L O   1 
ATOM   20209 C CB  . PHE H 3 61  ? 9.327   21.069  14.938 1.00 31.42  ? 83  PHE L CB  1 
ATOM   20210 C CG  . PHE H 3 61  ? 10.188  20.338  13.961 1.00 31.42  ? 83  PHE L CG  1 
ATOM   20211 C CD1 . PHE H 3 61  ? 9.821   20.243  12.639 1.00 31.42  ? 83  PHE L CD1 1 
ATOM   20212 C CD2 . PHE H 3 61  ? 11.353  19.726  14.373 1.00 31.42  ? 83  PHE L CD2 1 
ATOM   20213 C CE1 . PHE H 3 61  ? 10.607  19.562  11.737 1.00 31.42  ? 83  PHE L CE1 1 
ATOM   20214 C CE2 . PHE H 3 61  ? 12.145  19.040  13.479 1.00 31.42  ? 83  PHE L CE2 1 
ATOM   20215 C CZ  . PHE H 3 61  ? 11.771  18.958  12.157 1.00 31.42  ? 83  PHE L CZ  1 
ATOM   20216 N N   . SER H 3 62  ? 7.441   24.034  15.011 1.00 32.39  ? 84  SER L N   1 
ATOM   20217 C CA  . SER H 3 62  ? 6.310   24.651  15.696 1.00 32.39  ? 84  SER L CA  1 
ATOM   20218 C C   . SER H 3 62  ? 5.005   24.427  14.940 1.00 32.39  ? 84  SER L C   1 
ATOM   20219 O O   . SER H 3 62  ? 4.949   24.622  13.734 1.00 32.39  ? 84  SER L O   1 
ATOM   20220 C CB  . SER H 3 62  ? 6.554   26.144  15.883 1.00 35.18  ? 84  SER L CB  1 
ATOM   20221 O OG  . SER H 3 62  ? 5.494   26.745  16.598 1.00 35.18  ? 84  SER L OG  1 
ATOM   20222 N N   . GLY H 3 63  ? 3.947   24.049  15.650 1.00 26.75  ? 85  GLY L N   1 
ATOM   20223 C CA  . GLY H 3 63  ? 2.660   23.810  15.020 1.00 26.75  ? 85  GLY L CA  1 
ATOM   20224 C C   . GLY H 3 63  ? 1.520   24.568  15.666 1.00 26.75  ? 85  GLY L C   1 
ATOM   20225 O O   . GLY H 3 63  ? 1.466   24.692  16.880 1.00 26.75  ? 85  GLY L O   1 
ATOM   20226 N N   . SER H 3 64  ? 0.608   25.082  14.848 1.00 27.82  ? 86  SER L N   1 
ATOM   20227 C CA  . SER H 3 64  ? -0.530  25.848  15.344 1.00 27.82  ? 86  SER L CA  1 
ATOM   20228 C C   . SER H 3 64  ? -1.803  25.550  14.565 1.00 27.82  ? 86  SER L C   1 
ATOM   20229 O O   . SER H 3 64  ? -1.741  25.127  13.418 1.00 27.82  ? 86  SER L O   1 
ATOM   20230 C CB  . SER H 3 64  ? -0.232  27.344  15.257 1.00 29.97  ? 86  SER L CB  1 
ATOM   20231 O OG  . SER H 3 64  ? -0.090  27.753  13.908 1.00 29.97  ? 86  SER L OG  1 
ATOM   20232 N N   . LYS H 3 65  ? -2.954  25.746  15.195 1.00 31.15  ? 87  LYS L N   1 
ATOM   20233 C CA  . LYS H 3 65  ? -4.225  25.524  14.522 1.00 31.15  ? 87  LYS L CA  1 
ATOM   20234 C C   . LYS H 3 65  ? -5.178  26.699  14.644 1.00 31.15  ? 87  LYS L C   1 
ATOM   20235 O O   . LYS H 3 65  ? -5.434  27.178  15.742 1.00 31.15  ? 87  LYS L O   1 
ATOM   20236 C CB  . LYS H 3 65  ? -4.923  24.291  15.081 1.00 27.57  ? 87  LYS L CB  1 
ATOM   20237 C CG  . LYS H 3 65  ? -6.362  24.173  14.616 1.00 27.57  ? 87  LYS L CG  1 
ATOM   20238 C CD  . LYS H 3 65  ? -7.081  23.013  15.274 1.00 27.57  ? 87  LYS L CD  1 
ATOM   20239 C CE  . LYS H 3 65  ? -7.632  23.397  16.632 1.00 27.57  ? 87  LYS L CE  1 
ATOM   20240 N NZ  . LYS H 3 65  ? -8.567  22.357  17.133 1.00 27.57  ? 87  LYS L NZ  1 
ATOM   20241 N N   . SER H 3 66  ? -5.707  27.161  13.517 1.00 34.16  ? 88  SER L N   1 
ATOM   20242 C CA  . SER H 3 66  ? -6.683  28.245  13.524 1.00 34.16  ? 88  SER L CA  1 
ATOM   20243 C C   . SER H 3 66  ? -7.899  27.820  12.716 1.00 34.16  ? 88  SER L C   1 
ATOM   20244 O O   . SER H 3 66  ? -7.781  27.517  11.538 1.00 34.16  ? 88  SER L O   1 
ATOM   20245 C CB  . SER H 3 66  ? -6.085  29.516  12.928 1.00 36.81  ? 88  SER L CB  1 
ATOM   20246 O OG  . SER H 3 66  ? -6.016  29.429  11.519 1.00 36.81  ? 88  SER L OG  1 
ATOM   20247 N N   . GLY H 3 67  ? -9.080  27.858  13.315 1.00 33.09  ? 89  GLY L N   1 
ATOM   20248 C CA  . GLY H 3 67  ? -10.266 27.445  12.596 1.00 33.09  ? 89  GLY L CA  1 
ATOM   20249 C C   . GLY H 3 67  ? -10.150 26.004  12.144 1.00 33.09  ? 89  GLY L C   1 
ATOM   20250 O O   . GLY H 3 67  ? -9.870  25.124  12.947 1.00 33.09  ? 89  GLY L O   1 
ATOM   20251 N N   . THR H 3 68  ? -10.381 25.756  10.862 1.00 32.26  ? 90  THR L N   1 
ATOM   20252 C CA  . THR H 3 68  ? -10.307 24.405  10.320 1.00 32.26  ? 90  THR L CA  1 
ATOM   20253 C C   . THR H 3 68  ? -8.974  24.092  9.655  1.00 32.26  ? 90  THR L C   1 
ATOM   20254 O O   . THR H 3 68  ? -8.834  23.059  9.013  1.00 32.26  ? 90  THR L O   1 
ATOM   20255 C CB  . THR H 3 68  ? -11.444 24.113  9.324  1.00 31.78  ? 90  THR L CB  1 
ATOM   20256 O OG1 . THR H 3 68  ? -11.197 24.803  8.095  1.00 31.78  ? 90  THR L OG1 1 
ATOM   20257 C CG2 . THR H 3 68  ? -12.776 24.552  9.894  1.00 31.78  ? 90  THR L CG2 1 
ATOM   20258 N N   . SER H 3 69  ? -8.006  24.989  9.788  1.00 33.49  ? 91  SER L N   1 
ATOM   20259 C CA  . SER H 3 69  ? -6.692  24.792  9.183  1.00 33.49  ? 91  SER L CA  1 
ATOM   20260 C C   . SER H 3 69  ? -5.562  24.740  10.205 1.00 33.49  ? 91  SER L C   1 
ATOM   20261 O O   . SER H 3 69  ? -5.563  25.476  11.179 1.00 33.49  ? 91  SER L O   1 
ATOM   20262 C CB  . SER H 3 69  ? -6.412  25.893  8.165  1.00 34.02  ? 91  SER L CB  1 
ATOM   20263 O OG  . SER H 3 69  ? -7.420  25.927  7.174  1.00 34.02  ? 91  SER L OG  1 
ATOM   20264 N N   . ALA H 3 70  ? -4.608  23.846  9.995  1.00 29.01  ? 92  ALA L N   1 
ATOM   20265 C CA  . ALA H 3 70  ? -3.468  23.723  10.895 1.00 29.01  ? 92  ALA L CA  1 
ATOM   20266 C C   . ALA H 3 70  ? -2.171  23.912  10.121 1.00 29.01  ? 92  ALA L C   1 
ATOM   20267 O O   . ALA H 3 70  ? -2.021  23.375  9.034  1.00 29.01  ? 92  ALA L O   1 
ATOM   20268 C CB  . ALA H 3 70  ? -3.485  22.375  11.588 1.00 28.07  ? 92  ALA L CB  1 
ATOM   20269 N N   . SER H 3 71  ? -1.244  24.694  10.660 1.00 29.82  ? 93  SER L N   1 
ATOM   20270 C CA  . SER H 3 71  ? 0.030   24.921  9.981  1.00 29.82  ? 93  SER L CA  1 
ATOM   20271 C C   . SER H 3 71  ? 1.254   24.488  10.774 1.00 29.82  ? 93  SER L C   1 
ATOM   20272 O O   . SER H 3 71  ? 1.393   24.822  11.942 1.00 29.82  ? 93  SER L O   1 
ATOM   20273 C CB  . SER H 3 71  ? 0.187   26.393  9.600  1.00 34.94  ? 93  SER L CB  1 
ATOM   20274 O OG  . SER H 3 71  ? -0.226  26.632  8.267  1.00 34.94  ? 93  SER L OG  1 
ATOM   20275 N N   . LEU H 3 72  ? 2.145   23.748  10.127 1.00 28.75  ? 94  LEU L N   1 
ATOM   20276 C CA  . LEU H 3 72  ? 3.383   23.321  10.762 1.00 28.75  ? 94  LEU L CA  1 
ATOM   20277 C C   . LEU H 3 72  ? 4.515   24.156  10.172 1.00 28.75  ? 94  LEU L C   1 
ATOM   20278 O O   . LEU H 3 72  ? 4.742   24.129  8.971  1.00 28.75  ? 94  LEU L O   1 
ATOM   20279 C CB  . LEU H 3 72  ? 3.653   21.838  10.516 1.00 21.85  ? 94  LEU L CB  1 
ATOM   20280 C CG  . LEU H 3 72  ? 4.986   21.358  11.087 1.00 21.85  ? 94  LEU L CG  1 
ATOM   20281 C CD1 . LEU H 3 72  ? 4.870   21.066  12.568 1.00 21.85  ? 94  LEU L CD1 1 
ATOM   20282 C CD2 . LEU H 3 72  ? 5.514   20.149  10.348 1.00 21.85  ? 94  LEU L CD2 1 
ATOM   20283 N N   . ALA H 3 73  ? 5.194   24.927  11.009 1.00 30.81  ? 95  ALA L N   1 
ATOM   20284 C CA  . ALA H 3 73  ? 6.269   25.777  10.532 1.00 30.81  ? 95  ALA L CA  1 
ATOM   20285 C C   . ALA H 3 73  ? 7.626   25.286  10.973 1.00 30.81  ? 95  ALA L C   1 
ATOM   20286 O O   . ALA H 3 73  ? 7.816   24.912  12.122 1.00 30.81  ? 95  ALA L O   1 
ATOM   20287 C CB  . ALA H 3 73  ? 6.060   27.198  11.013 1.00 35.28  ? 95  ALA L CB  1 
ATOM   20288 N N   . ILE H 3 74  ? 8.574   25.290  10.049 1.00 35.62  ? 96  ILE L N   1 
ATOM   20289 C CA  . ILE H 3 74  ? 9.928   24.870  10.365 1.00 35.62  ? 96  ILE L CA  1 
ATOM   20290 C C   . ILE H 3 74  ? 10.891  26.034  10.158 1.00 35.62  ? 96  ILE L C   1 
ATOM   20291 O O   . ILE H 3 74  ? 10.930  26.645  9.098  1.00 35.62  ? 96  ILE L O   1 
ATOM   20292 C CB  . ILE H 3 74  ? 10.365  23.662  9.522  1.00 31.32  ? 96  ILE L CB  1 
ATOM   20293 C CG1 . ILE H 3 74  ? 9.253   22.615  9.492  1.00 31.32  ? 96  ILE L CG1 1 
ATOM   20294 C CG2 . ILE H 3 74  ? 11.646  23.070  10.081 1.00 31.32  ? 96  ILE L CG2 1 
ATOM   20295 C CD1 . ILE H 3 74  ? 9.552   21.421  8.615  1.00 31.32  ? 96  ILE L CD1 1 
ATOM   20296 N N   . SER H 3 75  ? 11.682  26.320  11.177 1.00 38.42  ? 97  SER L N   1 
ATOM   20297 C CA  . SER H 3 75  ? 12.640  27.402  11.123 1.00 38.42  ? 97  SER L CA  1 
ATOM   20298 C C   . SER H 3 75  ? 14.016  26.781  11.196 1.00 38.42  ? 97  SER L C   1 
ATOM   20299 O O   . SER H 3 75  ? 14.177  25.713  11.776 1.00 38.42  ? 97  SER L O   1 
ATOM   20300 C CB  . SER H 3 75  ? 12.435  28.340  12.303 1.00 37.21  ? 97  SER L CB  1 
ATOM   20301 O OG  . SER H 3 75  ? 12.841  27.722  13.507 1.00 37.21  ? 97  SER L OG  1 
ATOM   20302 N N   . GLY H 3 76  ? 15.019  27.449  10.638 1.00 43.37  ? 98  GLY L N   1 
ATOM   20303 C CA  . GLY H 3 76  ? 16.355  26.889  10.642 1.00 43.37  ? 98  GLY L CA  1 
ATOM   20304 C C   . GLY H 3 76  ? 16.355  25.534  9.966  1.00 43.37  ? 98  GLY L C   1 
ATOM   20305 O O   . GLY H 3 76  ? 16.882  24.558  10.490 1.00 43.37  ? 98  GLY L O   1 
ATOM   20306 N N   . LEU H 3 77  ? 15.760  25.491  8.779  1.00 44.79  ? 99  LEU L N   1 
ATOM   20307 C CA  . LEU H 3 77  ? 15.632  24.266  8.008  1.00 44.79  ? 99  LEU L CA  1 
ATOM   20308 C C   . LEU H 3 77  ? 16.996  23.659  7.739  1.00 44.79  ? 99  LEU L C   1 
ATOM   20309 O O   . LEU H 3 77  ? 17.958  24.359  7.436  1.00 44.79  ? 99  LEU L O   1 
ATOM   20310 C CB  . LEU H 3 77  ? 14.946  24.575  6.682  1.00 43.53  ? 99  LEU L CB  1 
ATOM   20311 C CG  . LEU H 3 77  ? 14.409  23.409  5.861  1.00 43.53  ? 99  LEU L CG  1 
ATOM   20312 C CD1 . LEU H 3 77  ? 13.094  22.936  6.453  1.00 43.53  ? 99  LEU L CD1 1 
ATOM   20313 C CD2 . LEU H 3 77  ? 14.207  23.849  4.425  1.00 43.53  ? 99  LEU L CD2 1 
ATOM   20314 N N   . ARG H 3 78  ? 17.060  22.338  7.834  1.00 43.60  ? 100 ARG L N   1 
ATOM   20315 C CA  . ARG H 3 78  ? 18.295  21.588  7.663  1.00 43.60  ? 100 ARG L CA  1 
ATOM   20316 C C   . ARG H 3 78  ? 18.119  20.458  6.680  1.00 43.60  ? 100 ARG L C   1 
ATOM   20317 O O   . ARG H 3 78  ? 17.000  20.118  6.312  1.00 43.60  ? 100 ARG L O   1 
ATOM   20318 C CB  . ARG H 3 78  ? 18.732  20.991  8.991  1.00 46.25  ? 100 ARG L CB  1 
ATOM   20319 C CG  . ARG H 3 78  ? 19.033  22.008  10.068 1.00 46.25  ? 100 ARG L CG  1 
ATOM   20320 C CD  . ARG H 3 78  ? 19.583  21.304  11.289 1.00 46.25  ? 100 ARG L CD  1 
ATOM   20321 N NE  . ARG H 3 78  ? 20.100  22.242  12.272 1.00 46.25  ? 100 ARG L NE  1 
ATOM   20322 C CZ  . ARG H 3 78  ? 20.605  21.878  13.443 1.00 46.25  ? 100 ARG L CZ  1 
ATOM   20323 N NH1 . ARG H 3 78  ? 21.058  22.794  14.289 1.00 46.25  ? 100 ARG L NH1 1 
ATOM   20324 N NH2 . ARG H 3 78  ? 20.655  20.594  13.768 1.00 46.25  ? 100 ARG L NH2 1 
ATOM   20325 N N   . SER H 3 79  ? 19.233  19.882  6.242  1.00 45.43  ? 101 SER L N   1 
ATOM   20326 C CA  . SER H 3 79  ? 19.206  18.764  5.306  1.00 45.43  ? 101 SER L CA  1 
ATOM   20327 C C   . SER H 3 79  ? 18.486  17.562  5.912  1.00 45.43  ? 101 SER L C   1 
ATOM   20328 O O   . SER H 3 79  ? 17.741  16.872  5.224  1.00 45.43  ? 101 SER L O   1 
ATOM   20329 C CB  . SER H 3 79  ? 20.622  18.377  4.900  1.00 43.69  ? 101 SER L CB  1 
ATOM   20330 O OG  . SER H 3 79  ? 21.330  19.504  4.424  1.00 43.69  ? 101 SER L OG  1 
ATOM   20331 N N   . GLU H 3 80  ? 18.680  17.355  7.211  1.00 46.92  ? 102 GLU L N   1 
ATOM   20332 C CA  . GLU H 3 80  ? 18.043  16.251  7.927  1.00 46.92  ? 102 GLU L CA  1 
ATOM   20333 C C   . GLU H 3 80  ? 16.555  16.493  8.167  1.00 46.92  ? 102 GLU L C   1 
ATOM   20334 O O   . GLU H 3 80  ? 15.846  15.617  8.649  1.00 46.92  ? 102 GLU L O   1 
ATOM   20335 C CB  . GLU H 3 80  ? 18.739  16.004  9.264  1.00 54.77  ? 102 GLU L CB  1 
ATOM   20336 C CG  . GLU H 3 80  ? 20.160  15.488  9.137  1.00 54.77  ? 102 GLU L CG  1 
ATOM   20337 C CD  . GLU H 3 80  ? 20.289  14.386  8.104  1.00 54.77  ? 102 GLU L CD  1 
ATOM   20338 O OE1 . GLU H 3 80  ? 20.517  13.222  8.496  1.00 54.77  ? 102 GLU L OE1 1 
ATOM   20339 O OE2 . GLU H 3 80  ? 20.157  14.684  6.900  1.00 54.77  ? 102 GLU L OE2 1 
ATOM   20340 N N   . ASP H 3 81  ? 16.084  17.682  7.811  1.00 39.53  ? 103 ASP L N   1 
ATOM   20341 C CA  . ASP H 3 81  ? 14.685  18.044  7.990  1.00 39.53  ? 103 ASP L CA  1 
ATOM   20342 C C   . ASP H 3 81  ? 13.854  17.754  6.751  1.00 39.53  ? 103 ASP L C   1 
ATOM   20343 O O   . ASP H 3 81  ? 12.670  18.073  6.697  1.00 39.53  ? 103 ASP L O   1 
ATOM   20344 C CB  . ASP H 3 81  ? 14.548  19.503  8.409  1.00 39.25  ? 103 ASP L CB  1 
ATOM   20345 C CG  . ASP H 3 81  ? 14.819  19.701  9.878  1.00 39.25  ? 103 ASP L CG  1 
ATOM   20346 O OD1 . ASP H 3 81  ? 15.089  18.693  10.559 1.00 39.25  ? 103 ASP L OD1 1 
ATOM   20347 O OD2 . ASP H 3 81  ? 14.764  20.851  10.355 1.00 39.25  ? 103 ASP L OD2 1 
ATOM   20348 N N   . GLU H 3 82  ? 14.490  17.154  5.755  1.00 38.49  ? 104 GLU L N   1 
ATOM   20349 C CA  . GLU H 3 82  ? 13.829  16.814  4.515  1.00 38.49  ? 104 GLU L CA  1 
ATOM   20350 C C   . GLU H 3 82  ? 13.243  15.418  4.617  1.00 38.49  ? 104 GLU L C   1 
ATOM   20351 O O   . GLU H 3 82  ? 13.978  14.438  4.716  1.00 38.49  ? 104 GLU L O   1 
ATOM   20352 C CB  . GLU H 3 82  ? 14.858  16.872  3.390  1.00 47.24  ? 104 GLU L CB  1 
ATOM   20353 C CG  . GLU H 3 82  ? 14.562  16.000  2.188  1.00 47.24  ? 104 GLU L CG  1 
ATOM   20354 C CD  . GLU H 3 82  ? 15.608  16.164  1.105  1.00 47.24  ? 104 GLU L CD  1 
ATOM   20355 O OE1 . GLU H 3 82  ? 16.543  16.965  1.303  1.00 47.24  ? 104 GLU L OE1 1 
ATOM   20356 O OE2 . GLU H 3 82  ? 15.499  15.493  0.059  1.00 47.24  ? 104 GLU L OE2 1 
ATOM   20357 N N   . ALA H 3 83  ? 11.915  15.343  4.563  1.00 31.37  ? 105 ALA L N   1 
ATOM   20358 C CA  . ALA H 3 83  ? 11.171  14.091  4.658  1.00 31.37  ? 105 ALA L CA  1 
ATOM   20359 C C   . ALA H 3 83  ? 9.734   14.342  4.248  1.00 31.37  ? 105 ALA L C   1 
ATOM   20360 O O   . ALA H 3 83  ? 9.418   15.391  3.711  1.00 31.37  ? 105 ALA L O   1 
ATOM   20361 C CB  . ALA H 3 83  ? 11.202  13.565  6.081  1.00 29.13  ? 105 ALA L CB  1 
ATOM   20362 N N   . ASP H 3 84  ? 8.865   13.368  4.484  1.00 25.73  ? 106 ASP L N   1 
ATOM   20363 C CA  . ASP H 3 84  ? 7.449   13.526  4.182  1.00 25.73  ? 106 ASP L CA  1 
ATOM   20364 C C   . ASP H 3 84  ? 6.731   13.855  5.477  1.00 25.73  ? 106 ASP L C   1 
ATOM   20365 O O   . ASP H 3 84  ? 7.012   13.259  6.506  1.00 25.73  ? 106 ASP L O   1 
ATOM   20366 C CB  . ASP H 3 84  ? 6.873   12.239  3.603  1.00 33.25  ? 106 ASP L CB  1 
ATOM   20367 C CG  . ASP H 3 84  ? 7.554   11.821  2.324  1.00 33.25  ? 106 ASP L CG  1 
ATOM   20368 O OD1 . ASP H 3 84  ? 8.510   12.503  1.907  1.00 33.25  ? 106 ASP L OD1 1 
ATOM   20369 O OD2 . ASP H 3 84  ? 7.135   10.809  1.731  1.00 33.25  ? 106 ASP L OD2 1 
ATOM   20370 N N   . TYR H 3 85  ? 5.803   14.801  5.429  1.00 22.81  ? 107 TYR L N   1 
ATOM   20371 C CA  . TYR H 3 85  ? 5.054   15.201  6.621  1.00 22.81  ? 107 TYR L CA  1 
ATOM   20372 C C   . TYR H 3 85  ? 3.589   14.825  6.527  1.00 22.81  ? 107 TYR L C   1 
ATOM   20373 O O   . TYR H 3 85  ? 2.935   15.080  5.526  1.00 22.81  ? 107 TYR L O   1 
ATOM   20374 C CB  . TYR H 3 85  ? 5.201   16.699  6.898  1.00 24.93  ? 107 TYR L CB  1 
ATOM   20375 C CG  . TYR H 3 85  ? 6.594   17.061  7.319  1.00 24.93  ? 107 TYR L CG  1 
ATOM   20376 C CD1 . TYR H 3 85  ? 6.936   17.145  8.651  1.00 24.93  ? 107 TYR L CD1 1 
ATOM   20377 C CD2 . TYR H 3 85  ? 7.575   17.287  6.380  1.00 24.93  ? 107 TYR L CD2 1 
ATOM   20378 C CE1 . TYR H 3 85  ? 8.221   17.454  9.034  1.00 24.93  ? 107 TYR L CE1 1 
ATOM   20379 C CE2 . TYR H 3 85  ? 8.861   17.594  6.752  1.00 24.93  ? 107 TYR L CE2 1 
ATOM   20380 C CZ  . TYR H 3 85  ? 9.177   17.675  8.079  1.00 24.93  ? 107 TYR L CZ  1 
ATOM   20381 O OH  . TYR H 3 85  ? 10.458  17.988  8.446  1.00 24.93  ? 107 TYR L OH  1 
ATOM   20382 N N   . TYR H 3 86  ? 3.084   14.207  7.586  1.00 20.53  ? 108 TYR L N   1 
ATOM   20383 C CA  . TYR H 3 86  ? 1.700   13.781  7.641  1.00 20.53  ? 108 TYR L CA  1 
ATOM   20384 C C   . TYR H 3 86  ? 0.949   14.531  8.716  1.00 20.53  ? 108 TYR L C   1 
ATOM   20385 O O   . TYR H 3 86  ? 1.416   14.670  9.832  1.00 20.53  ? 108 TYR L O   1 
ATOM   20386 C CB  . TYR H 3 86  ? 1.602   12.282  7.883  1.00 20.96  ? 108 TYR L CB  1 
ATOM   20387 C CG  . TYR H 3 86  ? 2.086   11.461  6.723  1.00 20.96  ? 108 TYR L CG  1 
ATOM   20388 C CD1 . TYR H 3 86  ? 1.279   11.239  5.624  1.00 20.96  ? 108 TYR L CD1 1 
ATOM   20389 C CD2 . TYR H 3 86  ? 3.353   10.911  6.725  1.00 20.96  ? 108 TYR L CD2 1 
ATOM   20390 C CE1 . TYR H 3 86  ? 1.722   10.492  4.559  1.00 20.96  ? 108 TYR L CE1 1 
ATOM   20391 C CE2 . TYR H 3 86  ? 3.800   10.159  5.666  1.00 20.96  ? 108 TYR L CE2 1 
ATOM   20392 C CZ  . TYR H 3 86  ? 2.980   9.955   4.588  1.00 20.96  ? 108 TYR L CZ  1 
ATOM   20393 O OH  . TYR H 3 86  ? 3.432   9.208   3.534  1.00 20.96  ? 108 TYR L OH  1 
ATOM   20394 N N   . CYS H 3 87  ? -0.230  15.004  8.358  1.00 19.02  ? 109 CYS L N   1 
ATOM   20395 C CA  . CYS H 3 87  ? -1.080  15.760  9.244  1.00 19.02  ? 109 CYS L CA  1 
ATOM   20396 C C   . CYS H 3 87  ? -2.192  14.837  9.698  1.00 19.02  ? 109 CYS L C   1 
ATOM   20397 O O   . CYS H 3 87  ? -2.811  14.174  8.876  1.00 19.02  ? 109 CYS L O   1 
ATOM   20398 C CB  . CYS H 3 87  ? -1.643  16.924  8.446  1.00 25.66  ? 109 CYS L CB  1 
ATOM   20399 S SG  . CYS H 3 87  ? -3.042  17.786  9.158  1.00 25.66  ? 109 CYS L SG  1 
ATOM   20400 N N   . ALA H 3 88  ? -2.434  14.760  11.003 1.00 15.87  ? 110 ALA L N   1 
ATOM   20401 C CA  . ALA H 3 88  ? -3.471  13.874  11.523 1.00 15.87  ? 110 ALA L CA  1 
ATOM   20402 C C   . ALA H 3 88  ? -4.372  14.513  12.570 1.00 15.87  ? 110 ALA L C   1 
ATOM   20403 O O   . ALA H 3 88  ? -3.938  15.363  13.330 1.00 15.87  ? 110 ALA L O   1 
ATOM   20404 C CB  . ALA H 3 88  ? -2.838  12.616  12.089 1.00 13.92  ? 110 ALA L CB  1 
ATOM   20405 N N   . ALA H 3 89  ? -5.639  14.116  12.581 1.00 13.50  ? 111 ALA L N   1 
ATOM   20406 C CA  . ALA H 3 89  ? -6.597  14.603  13.560 1.00 13.50  ? 111 ALA L CA  1 
ATOM   20407 C C   . ALA H 3 89  ? -7.739  13.612  13.647 1.00 13.50  ? 111 ALA L C   1 
ATOM   20408 O O   . ALA H 3 89  ? -7.954  12.857  12.716 1.00 13.50  ? 111 ALA L O   1 
ATOM   20409 C CB  . ALA H 3 89  ? -7.114  15.963  13.157 1.00 17.15  ? 111 ALA L CB  1 
ATOM   20410 N N   . TRP H 3 90  ? -8.470  13.603  14.755 1.00 15.17  ? 112 TRP L N   1 
ATOM   20411 C CA  . TRP H 3 90  ? -9.591  12.684  14.908 1.00 15.17  ? 112 TRP L CA  1 
ATOM   20412 C C   . TRP H 3 90  ? -10.778 13.214  14.133 1.00 15.17  ? 112 TRP L C   1 
ATOM   20413 O O   . TRP H 3 90  ? -11.028 14.401  14.132 1.00 15.17  ? 112 TRP L O   1 
ATOM   20414 C CB  . TRP H 3 90  ? -9.954  12.513  16.384 1.00 13.62  ? 112 TRP L CB  1 
ATOM   20415 C CG  . TRP H 3 90  ? -11.194 11.703  16.621 1.00 13.62  ? 112 TRP L CG  1 
ATOM   20416 C CD1 . TRP H 3 90  ? -12.423 12.173  16.944 1.00 13.62  ? 112 TRP L CD1 1 
ATOM   20417 C CD2 . TRP H 3 90  ? -11.322 10.281  16.538 1.00 13.62  ? 112 TRP L CD2 1 
ATOM   20418 N NE1 . TRP H 3 90  ? -13.310 11.142  17.070 1.00 13.62  ? 112 TRP L NE1 1 
ATOM   20419 C CE2 . TRP H 3 90  ? -12.657 9.966   16.823 1.00 13.62  ? 112 TRP L CE2 1 
ATOM   20420 C CE3 . TRP H 3 90  ? -10.437 9.246   16.245 1.00 13.62  ? 112 TRP L CE3 1 
ATOM   20421 C CZ2 . TRP H 3 90  ? -13.129 8.662   16.831 1.00 13.62  ? 112 TRP L CZ2 1 
ATOM   20422 C CZ3 . TRP H 3 90  ? -10.907 7.954   16.255 1.00 13.62  ? 112 TRP L CZ3 1 
ATOM   20423 C CH2 . TRP H 3 90  ? -12.239 7.673   16.546 1.00 13.62  ? 112 TRP L CH2 1 
ATOM   20424 N N   . ASP H 3 91  ? -11.501 12.339  13.454 1.00 18.19  ? 113 ASP L N   1 
ATOM   20425 C CA  . ASP H 3 91  ? -12.660 12.763  12.692 1.00 18.19  ? 113 ASP L CA  1 
ATOM   20426 C C   . ASP H 3 91  ? -13.925 12.239  13.347 1.00 18.19  ? 113 ASP L C   1 
ATOM   20427 O O   . ASP H 3 91  ? -14.109 11.040  13.467 1.00 18.19  ? 113 ASP L O   1 
ATOM   20428 C CB  . ASP H 3 91  ? -12.552 12.203  11.282 1.00 20.30  ? 113 ASP L CB  1 
ATOM   20429 C CG  . ASP H 3 91  ? -13.393 12.949  10.299 1.00 20.30  ? 113 ASP L CG  1 
ATOM   20430 O OD1 . ASP H 3 91  ? -14.200 13.783  10.737 1.00 20.30  ? 113 ASP L OD1 1 
ATOM   20431 O OD2 . ASP H 3 91  ? -13.246 12.705  9.088  1.00 20.30  ? 113 ASP L OD2 1 
ATOM   20432 N N   . ASP H 3 92  ? -14.787 13.144  13.784 1.00 23.60  ? 114 ASP L N   1 
ATOM   20433 C CA  . ASP H 3 92  ? -16.054 12.785  14.415 1.00 23.60  ? 114 ASP L CA  1 
ATOM   20434 C C   . ASP H 3 92  ? -17.053 12.111  13.484 1.00 23.60  ? 114 ASP L C   1 
ATOM   20435 O O   . ASP H 3 92  ? -17.786 11.224  13.888 1.00 23.60  ? 114 ASP L O   1 
ATOM   20436 C CB  . ASP H 3 92  ? -16.685 13.998  15.085 1.00 23.26  ? 114 ASP L CB  1 
ATOM   20437 C CG  . ASP H 3 92  ? -15.953 14.407  16.338 1.00 23.26  ? 114 ASP L CG  1 
ATOM   20438 O OD1 . ASP H 3 92  ? -15.676 13.530  17.179 1.00 23.26  ? 114 ASP L OD1 1 
ATOM   20439 O OD2 . ASP H 3 92  ? -15.660 15.608  16.488 1.00 23.26  ? 114 ASP L OD2 1 
ATOM   20440 N N   . SER H 3 93  ? -17.095 12.570  12.242 1.00 26.66  ? 115 SER L N   1 
ATOM   20441 C CA  . SER H 3 93  ? -18.023 12.063  11.240 1.00 26.66  ? 115 SER L CA  1 
ATOM   20442 C C   . SER H 3 93  ? -17.687 10.682  10.713 1.00 26.66  ? 115 SER L C   1 
ATOM   20443 O O   . SER H 3 93  ? -16.589 10.179  10.912 1.00 26.66  ? 115 SER L O   1 
ATOM   20444 C CB  . SER H 3 93  ? -18.104 13.024  10.062 1.00 30.35  ? 115 SER L CB  1 
ATOM   20445 O OG  . SER H 3 93  ? -16.969 12.884  9.231  1.00 30.35  ? 115 SER L OG  1 
ATOM   20446 N N   . LEU H 3 94  ? -18.673 10.065  10.065 1.00 30.49  ? 116 LEU L N   1 
ATOM   20447 C CA  . LEU H 3 94  ? -18.538 8.741   9.449  1.00 30.49  ? 116 LEU L CA  1 
ATOM   20448 C C   . LEU H 3 94  ? -18.016 7.646   10.370 1.00 30.49  ? 116 LEU L C   1 
ATOM   20449 O O   . LEU H 3 94  ? -17.042 6.958   10.039 1.00 30.49  ? 116 LEU L O   1 
ATOM   20450 C CB  . LEU H 3 94  ? -17.826 8.767   8.078  1.00 36.54  ? 116 LEU L CB  1 
ATOM   20451 C CG  . LEU H 3 94  ? -16.544 9.532   7.732  1.00 36.54  ? 116 LEU L CG  1 
ATOM   20452 C CD1 . LEU H 3 94  ? -15.307 8.844   8.283  1.00 36.54  ? 116 LEU L CD1 1 
ATOM   20453 C CD2 . LEU H 3 94  ? -16.429 9.678   6.225  1.00 36.54  ? 116 LEU L CD2 1 
ATOM   20454 N N   . SER H 3 95  ? -18.634 7.600   11.553 1.00 27.86  ? 117 SER L N   1 
ATOM   20455 C CA  . SER H 3 95  ? -18.422 6.633   12.643 1.00 27.86  ? 117 SER L CA  1 
ATOM   20456 C C   . SER H 3 95  ? -17.196 6.815   13.538 1.00 27.86  ? 117 SER L C   1 
ATOM   20457 O O   . SER H 3 95  ? -16.958 5.996   14.418 1.00 27.86  ? 117 SER L O   1 
ATOM   20458 C CB  . SER H 3 95  ? -18.581 5.172   12.195 1.00 27.55  ? 117 SER L CB  1 
ATOM   20459 O OG  . SER H 3 95  ? -17.862 4.311   13.049 1.00 27.55  ? 117 SER L OG  1 
ATOM   20460 N N   . GLY H 3 96  ? -16.428 7.874   13.324 1.00 20.76  ? 118 GLY L N   1 
ATOM   20461 C CA  . GLY H 3 96  ? -15.269 8.120   14.156 1.00 20.76  ? 118 GLY L CA  1 
ATOM   20462 C C   . GLY H 3 96  ? -14.012 7.481   13.614 1.00 20.76  ? 118 GLY L C   1 
ATOM   20463 O O   . GLY H 3 96  ? -13.824 6.276   13.759 1.00 20.76  ? 118 GLY L O   1 
ATOM   20464 N N   . ASN H 3 97  ? -13.145 8.284   13.009 1.00 15.93  ? 119 ASN L N   1 
ATOM   20465 C CA  . ASN H 3 97  ? -11.907 7.783   12.435 1.00 15.93  ? 119 ASN L CA  1 
ATOM   20466 C C   . ASN H 3 97  ? -10.738 8.699   12.711 1.00 15.93  ? 119 ASN L C   1 
ATOM   20467 O O   . ASN H 3 97  ? -10.920 9.884   12.896 1.00 15.93  ? 119 ASN L O   1 
ATOM   20468 C CB  . ASN H 3 97  ? -12.049 7.687   10.918 1.00 21.63  ? 119 ASN L CB  1 
ATOM   20469 C CG  . ASN H 3 97  ? -12.704 6.406   10.468 1.00 21.63  ? 119 ASN L CG  1 
ATOM   20470 O OD1 . ASN H 3 97  ? -12.604 5.380   11.128 1.00 21.63  ? 119 ASN L OD1 1 
ATOM   20471 N ND2 . ASN H 3 97  ? -13.365 6.456   9.323  1.00 21.63  ? 119 ASN L ND2 1 
ATOM   20472 N N   . TRP H 3 98  ? -9.536  8.141   12.746 1.00 13.29  ? 120 TRP L N   1 
ATOM   20473 C CA  . TRP H 3 98  ? -8.334  8.937   12.891 1.00 13.29  ? 120 TRP L CA  1 
ATOM   20474 C C   . TRP H 3 98  ? -7.937  9.112   11.440 1.00 13.29  ? 120 TRP L C   1 
ATOM   20475 O O   . TRP H 3 98  ? -7.795  8.145   10.713 1.00 13.29  ? 120 TRP L O   1 
ATOM   20476 C CB  . TRP H 3 98  ? -7.258  8.205   13.670 1.00 12.62  ? 120 TRP L CB  1 
ATOM   20477 C CG  . TRP H 3 98  ? -6.055  9.040   13.906 1.00 12.62  ? 120 TRP L CG  1 
ATOM   20478 C CD1 . TRP H 3 98  ? -4.908  9.037   13.187 1.00 12.62  ? 120 TRP L CD1 1 
ATOM   20479 C CD2 . TRP H 3 98  ? -5.883  10.010  14.933 1.00 12.62  ? 120 TRP L CD2 1 
ATOM   20480 N NE1 . TRP H 3 98  ? -4.028  9.946   13.700 1.00 12.62  ? 120 TRP L NE1 1 
ATOM   20481 C CE2 . TRP H 3 98  ? -4.604  10.557  14.777 1.00 12.62  ? 120 TRP L CE2 1 
ATOM   20482 C CE3 . TRP H 3 98  ? -6.687  10.469  15.972 1.00 12.62  ? 120 TRP L CE3 1 
ATOM   20483 C CZ2 . TRP H 3 98  ? -4.109  11.535  15.618 1.00 12.62  ? 120 TRP L CZ2 1 
ATOM   20484 C CZ3 . TRP H 3 98  ? -6.197  11.438  16.802 1.00 12.62  ? 120 TRP L CZ3 1 
ATOM   20485 C CH2 . TRP H 3 98  ? -4.921  11.966  16.622 1.00 12.62  ? 120 TRP L CH2 1 
ATOM   20486 N N   . VAL H 3 99  ? -7.742  10.346  11.019 1.00 13.92  ? 121 VAL L N   1 
ATOM   20487 C CA  . VAL H 3 99  ? -7.488  10.639  9.616  1.00 13.92  ? 121 VAL L CA  1 
ATOM   20488 C C   . VAL H 3 99  ? -6.079  11.194  9.471  1.00 13.92  ? 121 VAL L C   1 
ATOM   20489 O O   . VAL H 3 99  ? -5.671  12.076  10.233 1.00 13.92  ? 121 VAL L O   1 
ATOM   20490 C CB  . VAL H 3 99  ? -8.527  11.623  9.056  1.00 15.59  ? 121 VAL L CB  1 
ATOM   20491 C CG1 . VAL H 3 99  ? -8.213  11.958  7.617  1.00 15.59  ? 121 VAL L CG1 1 
ATOM   20492 C CG2 . VAL H 3 99  ? -9.916  11.036  9.174  1.00 15.59  ? 121 VAL L CG2 1 
ATOM   20493 N N   . PHE H 3 100 ? -5.341  10.674  8.496  1.00 16.15  ? 122 PHE L N   1 
ATOM   20494 C CA  . PHE H 3 100 ? -4.049  11.218  8.109  1.00 16.15  ? 122 PHE L CA  1 
ATOM   20495 C C   . PHE H 3 100 ? -4.202  12.055  6.849  1.00 16.15  ? 122 PHE L C   1 
ATOM   20496 O O   . PHE H 3 100 ? -5.023  11.747  5.982  1.00 16.15  ? 122 PHE L O   1 
ATOM   20497 C CB  . PHE H 3 100 ? -3.024  10.112  7.859  1.00 12.14  ? 122 PHE L CB  1 
ATOM   20498 C CG  . PHE H 3 100 ? -2.610  9.376   9.090  1.00 12.14  ? 122 PHE L CG  1 
ATOM   20499 C CD1 . PHE H 3 100 ? -1.619  9.884   9.907  1.00 12.14  ? 122 PHE L CD1 1 
ATOM   20500 C CD2 . PHE H 3 100 ? -3.195  8.174   9.424  1.00 12.14  ? 122 PHE L CD2 1 
ATOM   20501 C CE1 . PHE H 3 100 ? -1.226  9.212   11.036 1.00 12.14  ? 122 PHE L CE1 1 
ATOM   20502 C CE2 . PHE H 3 100 ? -2.805  7.497   10.554 1.00 12.14  ? 122 PHE L CE2 1 
ATOM   20503 C CZ  . PHE H 3 100 ? -1.819  8.018   11.361 1.00 12.14  ? 122 PHE L CZ  1 
ATOM   20504 N N   . GLY H 3 101 ? -3.413  13.115  6.756  1.00 18.47  ? 123 GLY L N   1 
ATOM   20505 C CA  . GLY H 3 101 ? -3.367  13.895  5.542  1.00 18.47  ? 123 GLY L CA  1 
ATOM   20506 C C   . GLY H 3 101 ? -2.711  13.132  4.408  1.00 18.47  ? 123 GLY L C   1 
ATOM   20507 O O   . GLY H 3 101 ? -2.167  12.040  4.573  1.00 18.47  ? 123 GLY L O   1 
ATOM   20508 N N   . GLY H 3 102 ? -2.765  13.734  3.220  1.00 23.41  ? 124 GLY L N   1 
ATOM   20509 C CA  . GLY H 3 102 ? -2.213  13.074  2.049  1.00 23.41  ? 124 GLY L CA  1 
ATOM   20510 C C   . GLY H 3 102 ? -0.700  12.993  2.080  1.00 23.41  ? 124 GLY L C   1 
ATOM   20511 O O   . GLY H 3 102 ? -0.099  12.141  1.421  1.00 23.41  ? 124 GLY L O   1 
ATOM   20512 N N   . GLY H 3 103 ? -0.066  13.865  2.854  1.00 25.47  ? 125 GLY L N   1 
ATOM   20513 C CA  . GLY H 3 103 ? 1.378   13.893  2.948  1.00 25.47  ? 125 GLY L CA  1 
ATOM   20514 C C   . GLY H 3 103 ? 2.004   15.035  2.179  1.00 25.47  ? 125 GLY L C   1 
ATOM   20515 O O   . GLY H 3 103 ? 1.480   15.468  1.151  1.00 25.47  ? 125 GLY L O   1 
ATOM   20516 N N   . THR H 3 104 ? 3.137   15.525  2.673  1.00 29.04  ? 126 THR L N   1 
ATOM   20517 C CA  . THR H 3 104 ? 3.892   16.595  2.039  1.00 29.04  ? 126 THR L CA  1 
ATOM   20518 C C   . THR H 3 104 ? 5.367   16.245  2.103  1.00 29.04  ? 126 THR L C   1 
ATOM   20519 O O   . THR H 3 104 ? 5.888   15.944  3.180  1.00 29.04  ? 126 THR L O   1 
ATOM   20520 C CB  . THR H 3 104 ? 3.653   17.937  2.728  1.00 29.67  ? 126 THR L CB  1 
ATOM   20521 O OG1 . THR H 3 104 ? 2.271   18.293  2.615  1.00 29.67  ? 126 THR L OG1 1 
ATOM   20522 C CG2 . THR H 3 104 ? 4.505   19.019  2.091  1.00 29.67  ? 126 THR L CG2 1 
ATOM   20523 N N   . LYS H 3 105 ? 6.038   16.284  0.959  1.00 34.36  ? 127 LYS L N   1 
ATOM   20524 C CA  . LYS H 3 105 ? 7.454   15.960  0.888  1.00 34.36  ? 127 LYS L CA  1 
ATOM   20525 C C   . LYS H 3 105 ? 8.250   17.256  0.836  1.00 34.36  ? 127 LYS L C   1 
ATOM   20526 O O   . LYS H 3 105 ? 8.221   17.968  -0.172 1.00 34.36  ? 127 LYS L O   1 
ATOM   20527 C CB  . LYS H 3 105 ? 7.757   15.086  -0.327 1.00 35.85  ? 127 LYS L CB  1 
ATOM   20528 C CG  . LYS H 3 105 ? 9.201   14.645  -0.406 1.00 35.85  ? 127 LYS L CG  1 
ATOM   20529 C CD  . LYS H 3 105 ? 9.445   13.786  -1.628 1.00 35.85  ? 127 LYS L CD  1 
ATOM   20530 C CE  . LYS H 3 105 ? 10.924  13.501  -1.805 1.00 35.85  ? 127 LYS L CE  1 
ATOM   20531 N NZ  . LYS H 3 105 ? 11.471  12.729  -0.656 1.00 35.85  ? 127 LYS L NZ  1 
ATOM   20532 N N   . LEU H 3 106 ? 8.955   17.554  1.919  1.00 37.06  ? 128 LEU L N   1 
ATOM   20533 C CA  . LEU H 3 106 ? 9.762   18.759  2.025  1.00 37.06  ? 128 LEU L CA  1 
ATOM   20534 C C   . LEU H 3 106 ? 11.143  18.481  1.457  1.00 37.06  ? 128 LEU L C   1 
ATOM   20535 O O   . LEU H 3 106 ? 11.819  17.547  1.894  1.00 37.06  ? 128 LEU L O   1 
ATOM   20536 C CB  . LEU H 3 106 ? 9.864   19.220  3.478  1.00 34.35  ? 128 LEU L CB  1 
ATOM   20537 C CG  . LEU H 3 106 ? 10.563  20.551  3.751  1.00 34.35  ? 128 LEU L CG  1 
ATOM   20538 C CD1 . LEU H 3 106 ? 9.924   21.238  4.932  1.00 34.35  ? 128 LEU L CD1 1 
ATOM   20539 C CD2 . LEU H 3 106 ? 12.030  20.329  4.026  1.00 34.35  ? 128 LEU L CD2 1 
ATOM   20540 N N   . THR H 3 107 ? 11.555  19.291  0.488  1.00 43.85  ? 129 THR L N   1 
ATOM   20541 C CA  . THR H 3 107 ? 12.854  19.158  -0.150 1.00 43.85  ? 129 THR L CA  1 
ATOM   20542 C C   . THR H 3 107 ? 13.710  20.367  0.193  1.00 43.85  ? 129 THR L C   1 
ATOM   20543 O O   . THR H 3 107 ? 13.266  21.510  0.061  1.00 43.85  ? 129 THR L O   1 
ATOM   20544 C CB  . THR H 3 107 ? 12.717  19.029  -1.670 1.00 46.92  ? 129 THR L CB  1 
ATOM   20545 O OG1 . THR H 3 107 ? 11.966  17.850  -1.984 1.00 46.92  ? 129 THR L OG1 1 
ATOM   20546 C CG2 . THR H 3 107 ? 14.084  18.940  -2.325 1.00 46.92  ? 129 THR L CG2 1 
ATOM   20547 N N   . VAL H 3 108 ? 14.934  20.110  0.635  1.00 48.75  ? 130 VAL L N   1 
ATOM   20548 C CA  . VAL H 3 108 ? 15.870  21.160  1.009  1.00 48.75  ? 130 VAL L CA  1 
ATOM   20549 C C   . VAL H 3 108 ? 16.737  21.453  -0.207 1.00 48.75  ? 130 VAL L C   1 
ATOM   20550 O O   . VAL H 3 108 ? 17.580  20.638  -0.595 1.00 48.75  ? 130 VAL L O   1 
ATOM   20551 C CB  . VAL H 3 108 ? 16.719  20.751  2.217  1.00 45.24  ? 130 VAL L CB  1 
ATOM   20552 C CG1 . VAL H 3 108 ? 17.715  21.839  2.553  1.00 45.24  ? 130 VAL L CG1 1 
ATOM   20553 C CG2 . VAL H 3 108 ? 15.823  20.446  3.402  1.00 45.24  ? 130 VAL L CG2 1 
ATOM   20554 N N   . LEU H 3 109 ? 16.536  22.623  -0.804 1.00 53.79  ? 131 LEU L N   1 
ATOM   20555 C CA  . LEU H 3 109 ? 17.256  22.986  -2.014 1.00 53.79  ? 131 LEU L CA  1 
ATOM   20556 C C   . LEU H 3 109 ? 18.653  23.497  -1.683 1.00 53.79  ? 131 LEU L C   1 
ATOM   20557 O O   . LEU H 3 109 ? 18.910  24.011  -0.592 1.00 53.79  ? 131 LEU L O   1 
ATOM   20558 C CB  . LEU H 3 109 ? 16.477  24.043  -2.792 1.00 51.81  ? 131 LEU L CB  1 
ATOM   20559 C CG  . LEU H 3 109 ? 15.119  23.568  -3.305 1.00 51.81  ? 131 LEU L CG  1 
ATOM   20560 C CD1 . LEU H 3 109 ? 14.351  24.708  -3.948 1.00 51.81  ? 131 LEU L CD1 1 
ATOM   20561 C CD2 . LEU H 3 109 ? 15.303  22.421  -4.281 1.00 51.81  ? 131 LEU L CD2 1 
ATOM   20562 N N   . GLY H 3 110 ? 19.559  23.350  -2.643 1.00 58.53  ? 132 GLY L N   1 
ATOM   20563 C CA  . GLY H 3 110 ? 20.924  23.813  -2.475 1.00 58.53  ? 132 GLY L CA  1 
ATOM   20564 C C   . GLY H 3 110 ? 21.876  22.727  -2.014 1.00 58.53  ? 132 GLY L C   1 
ATOM   20565 O O   . GLY H 3 110 ? 21.783  21.574  -2.435 1.00 58.53  ? 132 GLY L O   1 
ATOM   20566 O OXT . GLY H 3 110 ? 22.771  22.979  -1.208 1.00 63.63  ? 132 GLY L OXT 1 
HETATM 20567 O O   . HOH I 4 .   ? -15.608 3.788   20.214 1.00 24.29  ? 201 HOH H O   1 
# 
