data_9B4Y
# 
_entry.id   9B4Y 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9B4Y         pdb_00009b4y 10.2210/pdb9b4y/pdb 
WWPDB D_1000282193 ?            ?                   
EMDB  EMD-44191    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-03-26 ? 
2 'EM metadata'     1 0 2025-03-26 ? 
3 'Half map'        1 0 2025-03-26 1 
4 'Half map'        1 0 2025-03-26 2 
5 Image             1 0 2025-03-26 ? 
6 'Primary map'     1 0 2025-03-26 ? 
7 'Structure model' 1 1 2025-05-28 ? 
8 'EM metadata'     1 1 2025-05-28 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Half map'        repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 Image             repository 'Initial release' ? ? 
6 6 'Primary map'     repository 'Initial release' ? ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 7 'Structure model' 'Data collection'      
2 8 'EM metadata'     'Data processing'      
3 8 'EM metadata'     'Experimental summary' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 7 'Structure model' em_admin    
2 7 'Structure model' em_software 
3 8 'EM metadata'     em_admin    
4 8 'EM metadata'     em_software 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 7 'Structure model' '_em_admin.last_update' 
2 7 'Structure model' '_em_software.name'     
3 8 'EM metadata'     '_em_admin.last_update' 
4 8 'EM metadata'     '_em_software.name'     
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9B4Y 
_pdbx_database_status.recvd_initial_deposition_date   2024-03-21 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'cryo-EM structure of importin alpha-1/beta bound to TDP-43' 
_pdbx_database_related.db_id          EMD-44191 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              gcingola@uab.edu 
_pdbx_contact_author.name_first         Gino 
_pdbx_contact_author.name_last          Cingolani 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-9206-9640 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Ko, Y.'        1 ? 
'Cingolani, G.' 2 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Cryo-EM structure of importin alpha-1/beta bound to TDP-43' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Ko, Y.'        1 ? 
primary 'Cingolani, G.' 2 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Importin subunit beta-1'  97323.922 1 ? ? ? ? 
2 polymer man 'Importin subunit alpha-1' 5296.262  1 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Importin-90,Karyopherin subunit beta-1,Nuclear factor p97,Pore targeting complex 97 kDa subunit,PTAC97' 
2 'Karyopherin subunit alpha-2,RAG cohort protein 1,SRP1-alpha'                                            
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQIKNSLTSKDPDIKAQYQQRW
LAIDANARREVKNYVLHTLGTETYRPSSASQCVAGIACAEIPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQD
IDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIMQVVCEATQCPDTRVRVAALQN
LVKIMSLYYQYMETYMGPALFAITIEAMKSDIDEVALQGIEFWSNVCDEEMDLAIEASEAAEQGRPPEHTSKFYAKGALQ
YLVPILTQTLTKQDENDDDDDWNPCKAAGVCLMLLATCCEDDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPS
QLKPLVIQAMPTLIELMKDPSVVVRDTAAWTVGRICELLPEAAINDVYLAPLLQCLIEGLSAEPRVASNVCWAFSSLAEA
AYEAADVADDQEEPATYCLSSSFELIVQKLLETTDRPDGHQNNLRSSAYESLMEIVKNSAKDCYPAVQKTTLVIMERLQQ
VLQMESHIQSTSDRIQFNDLQSLLCATLQNVLRKVQHQDALQISDVVMASLLRMFQSTAGSGGVQEDALMAVSTLVEVLG
GEFLKYMEAFKPFLGIGLKNYAEYQVCLAAVGLVGDLCRALQSNIIPFCDEVMQLLLENLGNENVHRSVKPQILSVFGDI
ALAIGGEFKKYLEVVLNTLQQASQAQVDKSDYDMVDYLNELRESCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEFILSF
IDHIAGDEDHTDGVVACAAGLIGDLCTAFGKDVLKLVEARPMIHELLTEGRRSKTNKAKTLARWATKELRKLKNQA
;
;MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQIKNSLTSKDPDIKAQYQQRW
LAIDANARREVKNYVLHTLGTETYRPSSASQCVAGIACAEIPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQD
IDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIMQVVCEATQCPDTRVRVAALQN
LVKIMSLYYQYMETYMGPALFAITIEAMKSDIDEVALQGIEFWSNVCDEEMDLAIEASEAAEQGRPPEHTSKFYAKGALQ
YLVPILTQTLTKQDENDDDDDWNPCKAAGVCLMLLATCCEDDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPS
QLKPLVIQAMPTLIELMKDPSVVVRDTAAWTVGRICELLPEAAINDVYLAPLLQCLIEGLSAEPRVASNVCWAFSSLAEA
AYEAADVADDQEEPATYCLSSSFELIVQKLLETTDRPDGHQNNLRSSAYESLMEIVKNSAKDCYPAVQKTTLVIMERLQQ
VLQMESHIQSTSDRIQFNDLQSLLCATLQNVLRKVQHQDALQISDVVMASLLRMFQSTAGSGGVQEDALMAVSTLVEVLG
GEFLKYMEAFKPFLGIGLKNYAEYQVCLAAVGLVGDLCRALQSNIIPFCDEVMQLLLENLGNENVHRSVKPQILSVFGDI
ALAIGGEFKKYLEVVLNTLQQASQAQVDKSDYDMVDYLNELRESCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEFILSF
IDHIAGDEDHTDGVVACAAGLIGDLCTAFGKDVLKLVEARPMIHELLTEGRRSKTNKAKTLARWATKELRKLKNQA
;
A ? 
2 'polypeptide(L)' no no AARLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNV AARLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNV B ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLU n 
1 3   LEU n 
1 4   ILE n 
1 5   THR n 
1 6   ILE n 
1 7   LEU n 
1 8   GLU n 
1 9   LYS n 
1 10  THR n 
1 11  VAL n 
1 12  SER n 
1 13  PRO n 
1 14  ASP n 
1 15  ARG n 
1 16  LEU n 
1 17  GLU n 
1 18  LEU n 
1 19  GLU n 
1 20  ALA n 
1 21  ALA n 
1 22  GLN n 
1 23  LYS n 
1 24  PHE n 
1 25  LEU n 
1 26  GLU n 
1 27  ARG n 
1 28  ALA n 
1 29  ALA n 
1 30  VAL n 
1 31  GLU n 
1 32  ASN n 
1 33  LEU n 
1 34  PRO n 
1 35  THR n 
1 36  PHE n 
1 37  LEU n 
1 38  VAL n 
1 39  GLU n 
1 40  LEU n 
1 41  SER n 
1 42  ARG n 
1 43  VAL n 
1 44  LEU n 
1 45  ALA n 
1 46  ASN n 
1 47  PRO n 
1 48  GLY n 
1 49  ASN n 
1 50  SER n 
1 51  GLN n 
1 52  VAL n 
1 53  ALA n 
1 54  ARG n 
1 55  VAL n 
1 56  ALA n 
1 57  ALA n 
1 58  GLY n 
1 59  LEU n 
1 60  GLN n 
1 61  ILE n 
1 62  LYS n 
1 63  ASN n 
1 64  SER n 
1 65  LEU n 
1 66  THR n 
1 67  SER n 
1 68  LYS n 
1 69  ASP n 
1 70  PRO n 
1 71  ASP n 
1 72  ILE n 
1 73  LYS n 
1 74  ALA n 
1 75  GLN n 
1 76  TYR n 
1 77  GLN n 
1 78  GLN n 
1 79  ARG n 
1 80  TRP n 
1 81  LEU n 
1 82  ALA n 
1 83  ILE n 
1 84  ASP n 
1 85  ALA n 
1 86  ASN n 
1 87  ALA n 
1 88  ARG n 
1 89  ARG n 
1 90  GLU n 
1 91  VAL n 
1 92  LYS n 
1 93  ASN n 
1 94  TYR n 
1 95  VAL n 
1 96  LEU n 
1 97  HIS n 
1 98  THR n 
1 99  LEU n 
1 100 GLY n 
1 101 THR n 
1 102 GLU n 
1 103 THR n 
1 104 TYR n 
1 105 ARG n 
1 106 PRO n 
1 107 SER n 
1 108 SER n 
1 109 ALA n 
1 110 SER n 
1 111 GLN n 
1 112 CYS n 
1 113 VAL n 
1 114 ALA n 
1 115 GLY n 
1 116 ILE n 
1 117 ALA n 
1 118 CYS n 
1 119 ALA n 
1 120 GLU n 
1 121 ILE n 
1 122 PRO n 
1 123 VAL n 
1 124 ASN n 
1 125 GLN n 
1 126 TRP n 
1 127 PRO n 
1 128 GLU n 
1 129 LEU n 
1 130 ILE n 
1 131 PRO n 
1 132 GLN n 
1 133 LEU n 
1 134 VAL n 
1 135 ALA n 
1 136 ASN n 
1 137 VAL n 
1 138 THR n 
1 139 ASN n 
1 140 PRO n 
1 141 ASN n 
1 142 SER n 
1 143 THR n 
1 144 GLU n 
1 145 HIS n 
1 146 MET n 
1 147 LYS n 
1 148 GLU n 
1 149 SER n 
1 150 THR n 
1 151 LEU n 
1 152 GLU n 
1 153 ALA n 
1 154 ILE n 
1 155 GLY n 
1 156 TYR n 
1 157 ILE n 
1 158 CYS n 
1 159 GLN n 
1 160 ASP n 
1 161 ILE n 
1 162 ASP n 
1 163 PRO n 
1 164 GLU n 
1 165 GLN n 
1 166 LEU n 
1 167 GLN n 
1 168 ASP n 
1 169 LYS n 
1 170 SER n 
1 171 ASN n 
1 172 GLU n 
1 173 ILE n 
1 174 LEU n 
1 175 THR n 
1 176 ALA n 
1 177 ILE n 
1 178 ILE n 
1 179 GLN n 
1 180 GLY n 
1 181 MET n 
1 182 ARG n 
1 183 LYS n 
1 184 GLU n 
1 185 GLU n 
1 186 PRO n 
1 187 SER n 
1 188 ASN n 
1 189 ASN n 
1 190 VAL n 
1 191 LYS n 
1 192 LEU n 
1 193 ALA n 
1 194 ALA n 
1 195 THR n 
1 196 ASN n 
1 197 ALA n 
1 198 LEU n 
1 199 LEU n 
1 200 ASN n 
1 201 SER n 
1 202 LEU n 
1 203 GLU n 
1 204 PHE n 
1 205 THR n 
1 206 LYS n 
1 207 ALA n 
1 208 ASN n 
1 209 PHE n 
1 210 ASP n 
1 211 LYS n 
1 212 GLU n 
1 213 SER n 
1 214 GLU n 
1 215 ARG n 
1 216 HIS n 
1 217 PHE n 
1 218 ILE n 
1 219 MET n 
1 220 GLN n 
1 221 VAL n 
1 222 VAL n 
1 223 CYS n 
1 224 GLU n 
1 225 ALA n 
1 226 THR n 
1 227 GLN n 
1 228 CYS n 
1 229 PRO n 
1 230 ASP n 
1 231 THR n 
1 232 ARG n 
1 233 VAL n 
1 234 ARG n 
1 235 VAL n 
1 236 ALA n 
1 237 ALA n 
1 238 LEU n 
1 239 GLN n 
1 240 ASN n 
1 241 LEU n 
1 242 VAL n 
1 243 LYS n 
1 244 ILE n 
1 245 MET n 
1 246 SER n 
1 247 LEU n 
1 248 TYR n 
1 249 TYR n 
1 250 GLN n 
1 251 TYR n 
1 252 MET n 
1 253 GLU n 
1 254 THR n 
1 255 TYR n 
1 256 MET n 
1 257 GLY n 
1 258 PRO n 
1 259 ALA n 
1 260 LEU n 
1 261 PHE n 
1 262 ALA n 
1 263 ILE n 
1 264 THR n 
1 265 ILE n 
1 266 GLU n 
1 267 ALA n 
1 268 MET n 
1 269 LYS n 
1 270 SER n 
1 271 ASP n 
1 272 ILE n 
1 273 ASP n 
1 274 GLU n 
1 275 VAL n 
1 276 ALA n 
1 277 LEU n 
1 278 GLN n 
1 279 GLY n 
1 280 ILE n 
1 281 GLU n 
1 282 PHE n 
1 283 TRP n 
1 284 SER n 
1 285 ASN n 
1 286 VAL n 
1 287 CYS n 
1 288 ASP n 
1 289 GLU n 
1 290 GLU n 
1 291 MET n 
1 292 ASP n 
1 293 LEU n 
1 294 ALA n 
1 295 ILE n 
1 296 GLU n 
1 297 ALA n 
1 298 SER n 
1 299 GLU n 
1 300 ALA n 
1 301 ALA n 
1 302 GLU n 
1 303 GLN n 
1 304 GLY n 
1 305 ARG n 
1 306 PRO n 
1 307 PRO n 
1 308 GLU n 
1 309 HIS n 
1 310 THR n 
1 311 SER n 
1 312 LYS n 
1 313 PHE n 
1 314 TYR n 
1 315 ALA n 
1 316 LYS n 
1 317 GLY n 
1 318 ALA n 
1 319 LEU n 
1 320 GLN n 
1 321 TYR n 
1 322 LEU n 
1 323 VAL n 
1 324 PRO n 
1 325 ILE n 
1 326 LEU n 
1 327 THR n 
1 328 GLN n 
1 329 THR n 
1 330 LEU n 
1 331 THR n 
1 332 LYS n 
1 333 GLN n 
1 334 ASP n 
1 335 GLU n 
1 336 ASN n 
1 337 ASP n 
1 338 ASP n 
1 339 ASP n 
1 340 ASP n 
1 341 ASP n 
1 342 TRP n 
1 343 ASN n 
1 344 PRO n 
1 345 CYS n 
1 346 LYS n 
1 347 ALA n 
1 348 ALA n 
1 349 GLY n 
1 350 VAL n 
1 351 CYS n 
1 352 LEU n 
1 353 MET n 
1 354 LEU n 
1 355 LEU n 
1 356 ALA n 
1 357 THR n 
1 358 CYS n 
1 359 CYS n 
1 360 GLU n 
1 361 ASP n 
1 362 ASP n 
1 363 ILE n 
1 364 VAL n 
1 365 PRO n 
1 366 HIS n 
1 367 VAL n 
1 368 LEU n 
1 369 PRO n 
1 370 PHE n 
1 371 ILE n 
1 372 LYS n 
1 373 GLU n 
1 374 HIS n 
1 375 ILE n 
1 376 LYS n 
1 377 ASN n 
1 378 PRO n 
1 379 ASP n 
1 380 TRP n 
1 381 ARG n 
1 382 TYR n 
1 383 ARG n 
1 384 ASP n 
1 385 ALA n 
1 386 ALA n 
1 387 VAL n 
1 388 MET n 
1 389 ALA n 
1 390 PHE n 
1 391 GLY n 
1 392 CYS n 
1 393 ILE n 
1 394 LEU n 
1 395 GLU n 
1 396 GLY n 
1 397 PRO n 
1 398 GLU n 
1 399 PRO n 
1 400 SER n 
1 401 GLN n 
1 402 LEU n 
1 403 LYS n 
1 404 PRO n 
1 405 LEU n 
1 406 VAL n 
1 407 ILE n 
1 408 GLN n 
1 409 ALA n 
1 410 MET n 
1 411 PRO n 
1 412 THR n 
1 413 LEU n 
1 414 ILE n 
1 415 GLU n 
1 416 LEU n 
1 417 MET n 
1 418 LYS n 
1 419 ASP n 
1 420 PRO n 
1 421 SER n 
1 422 VAL n 
1 423 VAL n 
1 424 VAL n 
1 425 ARG n 
1 426 ASP n 
1 427 THR n 
1 428 ALA n 
1 429 ALA n 
1 430 TRP n 
1 431 THR n 
1 432 VAL n 
1 433 GLY n 
1 434 ARG n 
1 435 ILE n 
1 436 CYS n 
1 437 GLU n 
1 438 LEU n 
1 439 LEU n 
1 440 PRO n 
1 441 GLU n 
1 442 ALA n 
1 443 ALA n 
1 444 ILE n 
1 445 ASN n 
1 446 ASP n 
1 447 VAL n 
1 448 TYR n 
1 449 LEU n 
1 450 ALA n 
1 451 PRO n 
1 452 LEU n 
1 453 LEU n 
1 454 GLN n 
1 455 CYS n 
1 456 LEU n 
1 457 ILE n 
1 458 GLU n 
1 459 GLY n 
1 460 LEU n 
1 461 SER n 
1 462 ALA n 
1 463 GLU n 
1 464 PRO n 
1 465 ARG n 
1 466 VAL n 
1 467 ALA n 
1 468 SER n 
1 469 ASN n 
1 470 VAL n 
1 471 CYS n 
1 472 TRP n 
1 473 ALA n 
1 474 PHE n 
1 475 SER n 
1 476 SER n 
1 477 LEU n 
1 478 ALA n 
1 479 GLU n 
1 480 ALA n 
1 481 ALA n 
1 482 TYR n 
1 483 GLU n 
1 484 ALA n 
1 485 ALA n 
1 486 ASP n 
1 487 VAL n 
1 488 ALA n 
1 489 ASP n 
1 490 ASP n 
1 491 GLN n 
1 492 GLU n 
1 493 GLU n 
1 494 PRO n 
1 495 ALA n 
1 496 THR n 
1 497 TYR n 
1 498 CYS n 
1 499 LEU n 
1 500 SER n 
1 501 SER n 
1 502 SER n 
1 503 PHE n 
1 504 GLU n 
1 505 LEU n 
1 506 ILE n 
1 507 VAL n 
1 508 GLN n 
1 509 LYS n 
1 510 LEU n 
1 511 LEU n 
1 512 GLU n 
1 513 THR n 
1 514 THR n 
1 515 ASP n 
1 516 ARG n 
1 517 PRO n 
1 518 ASP n 
1 519 GLY n 
1 520 HIS n 
1 521 GLN n 
1 522 ASN n 
1 523 ASN n 
1 524 LEU n 
1 525 ARG n 
1 526 SER n 
1 527 SER n 
1 528 ALA n 
1 529 TYR n 
1 530 GLU n 
1 531 SER n 
1 532 LEU n 
1 533 MET n 
1 534 GLU n 
1 535 ILE n 
1 536 VAL n 
1 537 LYS n 
1 538 ASN n 
1 539 SER n 
1 540 ALA n 
1 541 LYS n 
1 542 ASP n 
1 543 CYS n 
1 544 TYR n 
1 545 PRO n 
1 546 ALA n 
1 547 VAL n 
1 548 GLN n 
1 549 LYS n 
1 550 THR n 
1 551 THR n 
1 552 LEU n 
1 553 VAL n 
1 554 ILE n 
1 555 MET n 
1 556 GLU n 
1 557 ARG n 
1 558 LEU n 
1 559 GLN n 
1 560 GLN n 
1 561 VAL n 
1 562 LEU n 
1 563 GLN n 
1 564 MET n 
1 565 GLU n 
1 566 SER n 
1 567 HIS n 
1 568 ILE n 
1 569 GLN n 
1 570 SER n 
1 571 THR n 
1 572 SER n 
1 573 ASP n 
1 574 ARG n 
1 575 ILE n 
1 576 GLN n 
1 577 PHE n 
1 578 ASN n 
1 579 ASP n 
1 580 LEU n 
1 581 GLN n 
1 582 SER n 
1 583 LEU n 
1 584 LEU n 
1 585 CYS n 
1 586 ALA n 
1 587 THR n 
1 588 LEU n 
1 589 GLN n 
1 590 ASN n 
1 591 VAL n 
1 592 LEU n 
1 593 ARG n 
1 594 LYS n 
1 595 VAL n 
1 596 GLN n 
1 597 HIS n 
1 598 GLN n 
1 599 ASP n 
1 600 ALA n 
1 601 LEU n 
1 602 GLN n 
1 603 ILE n 
1 604 SER n 
1 605 ASP n 
1 606 VAL n 
1 607 VAL n 
1 608 MET n 
1 609 ALA n 
1 610 SER n 
1 611 LEU n 
1 612 LEU n 
1 613 ARG n 
1 614 MET n 
1 615 PHE n 
1 616 GLN n 
1 617 SER n 
1 618 THR n 
1 619 ALA n 
1 620 GLY n 
1 621 SER n 
1 622 GLY n 
1 623 GLY n 
1 624 VAL n 
1 625 GLN n 
1 626 GLU n 
1 627 ASP n 
1 628 ALA n 
1 629 LEU n 
1 630 MET n 
1 631 ALA n 
1 632 VAL n 
1 633 SER n 
1 634 THR n 
1 635 LEU n 
1 636 VAL n 
1 637 GLU n 
1 638 VAL n 
1 639 LEU n 
1 640 GLY n 
1 641 GLY n 
1 642 GLU n 
1 643 PHE n 
1 644 LEU n 
1 645 LYS n 
1 646 TYR n 
1 647 MET n 
1 648 GLU n 
1 649 ALA n 
1 650 PHE n 
1 651 LYS n 
1 652 PRO n 
1 653 PHE n 
1 654 LEU n 
1 655 GLY n 
1 656 ILE n 
1 657 GLY n 
1 658 LEU n 
1 659 LYS n 
1 660 ASN n 
1 661 TYR n 
1 662 ALA n 
1 663 GLU n 
1 664 TYR n 
1 665 GLN n 
1 666 VAL n 
1 667 CYS n 
1 668 LEU n 
1 669 ALA n 
1 670 ALA n 
1 671 VAL n 
1 672 GLY n 
1 673 LEU n 
1 674 VAL n 
1 675 GLY n 
1 676 ASP n 
1 677 LEU n 
1 678 CYS n 
1 679 ARG n 
1 680 ALA n 
1 681 LEU n 
1 682 GLN n 
1 683 SER n 
1 684 ASN n 
1 685 ILE n 
1 686 ILE n 
1 687 PRO n 
1 688 PHE n 
1 689 CYS n 
1 690 ASP n 
1 691 GLU n 
1 692 VAL n 
1 693 MET n 
1 694 GLN n 
1 695 LEU n 
1 696 LEU n 
1 697 LEU n 
1 698 GLU n 
1 699 ASN n 
1 700 LEU n 
1 701 GLY n 
1 702 ASN n 
1 703 GLU n 
1 704 ASN n 
1 705 VAL n 
1 706 HIS n 
1 707 ARG n 
1 708 SER n 
1 709 VAL n 
1 710 LYS n 
1 711 PRO n 
1 712 GLN n 
1 713 ILE n 
1 714 LEU n 
1 715 SER n 
1 716 VAL n 
1 717 PHE n 
1 718 GLY n 
1 719 ASP n 
1 720 ILE n 
1 721 ALA n 
1 722 LEU n 
1 723 ALA n 
1 724 ILE n 
1 725 GLY n 
1 726 GLY n 
1 727 GLU n 
1 728 PHE n 
1 729 LYS n 
1 730 LYS n 
1 731 TYR n 
1 732 LEU n 
1 733 GLU n 
1 734 VAL n 
1 735 VAL n 
1 736 LEU n 
1 737 ASN n 
1 738 THR n 
1 739 LEU n 
1 740 GLN n 
1 741 GLN n 
1 742 ALA n 
1 743 SER n 
1 744 GLN n 
1 745 ALA n 
1 746 GLN n 
1 747 VAL n 
1 748 ASP n 
1 749 LYS n 
1 750 SER n 
1 751 ASP n 
1 752 TYR n 
1 753 ASP n 
1 754 MET n 
1 755 VAL n 
1 756 ASP n 
1 757 TYR n 
1 758 LEU n 
1 759 ASN n 
1 760 GLU n 
1 761 LEU n 
1 762 ARG n 
1 763 GLU n 
1 764 SER n 
1 765 CYS n 
1 766 LEU n 
1 767 GLU n 
1 768 ALA n 
1 769 TYR n 
1 770 THR n 
1 771 GLY n 
1 772 ILE n 
1 773 VAL n 
1 774 GLN n 
1 775 GLY n 
1 776 LEU n 
1 777 LYS n 
1 778 GLY n 
1 779 ASP n 
1 780 GLN n 
1 781 GLU n 
1 782 ASN n 
1 783 VAL n 
1 784 HIS n 
1 785 PRO n 
1 786 ASP n 
1 787 VAL n 
1 788 MET n 
1 789 LEU n 
1 790 VAL n 
1 791 GLN n 
1 792 PRO n 
1 793 ARG n 
1 794 VAL n 
1 795 GLU n 
1 796 PHE n 
1 797 ILE n 
1 798 LEU n 
1 799 SER n 
1 800 PHE n 
1 801 ILE n 
1 802 ASP n 
1 803 HIS n 
1 804 ILE n 
1 805 ALA n 
1 806 GLY n 
1 807 ASP n 
1 808 GLU n 
1 809 ASP n 
1 810 HIS n 
1 811 THR n 
1 812 ASP n 
1 813 GLY n 
1 814 VAL n 
1 815 VAL n 
1 816 ALA n 
1 817 CYS n 
1 818 ALA n 
1 819 ALA n 
1 820 GLY n 
1 821 LEU n 
1 822 ILE n 
1 823 GLY n 
1 824 ASP n 
1 825 LEU n 
1 826 CYS n 
1 827 THR n 
1 828 ALA n 
1 829 PHE n 
1 830 GLY n 
1 831 LYS n 
1 832 ASP n 
1 833 VAL n 
1 834 LEU n 
1 835 LYS n 
1 836 LEU n 
1 837 VAL n 
1 838 GLU n 
1 839 ALA n 
1 840 ARG n 
1 841 PRO n 
1 842 MET n 
1 843 ILE n 
1 844 HIS n 
1 845 GLU n 
1 846 LEU n 
1 847 LEU n 
1 848 THR n 
1 849 GLU n 
1 850 GLY n 
1 851 ARG n 
1 852 ARG n 
1 853 SER n 
1 854 LYS n 
1 855 THR n 
1 856 ASN n 
1 857 LYS n 
1 858 ALA n 
1 859 LYS n 
1 860 THR n 
1 861 LEU n 
1 862 ALA n 
1 863 ARG n 
1 864 TRP n 
1 865 ALA n 
1 866 THR n 
1 867 LYS n 
1 868 GLU n 
1 869 LEU n 
1 870 ARG n 
1 871 LYS n 
1 872 LEU n 
1 873 LYS n 
1 874 ASN n 
1 875 GLN n 
1 876 ALA n 
2 1   ALA n 
2 2   ALA n 
2 3   ARG n 
2 4   LEU n 
2 5   HIS n 
2 6   ARG n 
2 7   PHE n 
2 8   LYS n 
2 9   ASN n 
2 10  LYS n 
2 11  GLY n 
2 12  LYS n 
2 13  ASP n 
2 14  SER n 
2 15  THR n 
2 16  GLU n 
2 17  MET n 
2 18  ARG n 
2 19  ARG n 
2 20  ARG n 
2 21  ARG n 
2 22  ILE n 
2 23  GLU n 
2 24  VAL n 
2 25  ASN n 
2 26  VAL n 
2 27  GLU n 
2 28  LEU n 
2 29  ARG n 
2 30  LYS n 
2 31  ALA n 
2 32  LYS n 
2 33  LYS n 
2 34  ASP n 
2 35  ASP n 
2 36  GLN n 
2 37  MET n 
2 38  LEU n 
2 39  LYS n 
2 40  ARG n 
2 41  ARG n 
2 42  ASN n 
2 43  VAL n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 876 human ? 'KPNB1, NTF97'      ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Escherichia coli' 562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 43  human ? 'KPNA2, RCH1, SRP1' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Escherichia coli' 562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   1   MET MET A . n 
A 1 2   GLU 2   2   2   GLU GLU A . n 
A 1 3   LEU 3   3   3   LEU LEU A . n 
A 1 4   ILE 4   4   4   ILE ILE A . n 
A 1 5   THR 5   5   5   THR THR A . n 
A 1 6   ILE 6   6   6   ILE ILE A . n 
A 1 7   LEU 7   7   7   LEU LEU A . n 
A 1 8   GLU 8   8   8   GLU GLU A . n 
A 1 9   LYS 9   9   9   LYS LYS A . n 
A 1 10  THR 10  10  10  THR THR A . n 
A 1 11  VAL 11  11  11  VAL VAL A . n 
A 1 12  SER 12  12  12  SER SER A . n 
A 1 13  PRO 13  13  13  PRO PRO A . n 
A 1 14  ASP 14  14  14  ASP ASP A . n 
A 1 15  ARG 15  15  15  ARG ARG A . n 
A 1 16  LEU 16  16  16  LEU LEU A . n 
A 1 17  GLU 17  17  17  GLU GLU A . n 
A 1 18  LEU 18  18  18  LEU LEU A . n 
A 1 19  GLU 19  19  19  GLU GLU A . n 
A 1 20  ALA 20  20  20  ALA ALA A . n 
A 1 21  ALA 21  21  21  ALA ALA A . n 
A 1 22  GLN 22  22  22  GLN GLN A . n 
A 1 23  LYS 23  23  23  LYS LYS A . n 
A 1 24  PHE 24  24  24  PHE PHE A . n 
A 1 25  LEU 25  25  25  LEU LEU A . n 
A 1 26  GLU 26  26  26  GLU GLU A . n 
A 1 27  ARG 27  27  27  ARG ARG A . n 
A 1 28  ALA 28  28  28  ALA ALA A . n 
A 1 29  ALA 29  29  29  ALA ALA A . n 
A 1 30  VAL 30  30  30  VAL VAL A . n 
A 1 31  GLU 31  31  31  GLU GLU A . n 
A 1 32  ASN 32  32  32  ASN ASN A . n 
A 1 33  LEU 33  33  33  LEU LEU A . n 
A 1 34  PRO 34  34  34  PRO PRO A . n 
A 1 35  THR 35  35  35  THR THR A . n 
A 1 36  PHE 36  36  36  PHE PHE A . n 
A 1 37  LEU 37  37  37  LEU LEU A . n 
A 1 38  VAL 38  38  38  VAL VAL A . n 
A 1 39  GLU 39  39  39  GLU GLU A . n 
A 1 40  LEU 40  40  40  LEU LEU A . n 
A 1 41  SER 41  41  41  SER SER A . n 
A 1 42  ARG 42  42  42  ARG ARG A . n 
A 1 43  VAL 43  43  43  VAL VAL A . n 
A 1 44  LEU 44  44  44  LEU LEU A . n 
A 1 45  ALA 45  45  45  ALA ALA A . n 
A 1 46  ASN 46  46  46  ASN ASN A . n 
A 1 47  PRO 47  47  47  PRO PRO A . n 
A 1 48  GLY 48  48  48  GLY GLY A . n 
A 1 49  ASN 49  49  49  ASN ASN A . n 
A 1 50  SER 50  50  50  SER SER A . n 
A 1 51  GLN 51  51  51  GLN GLN A . n 
A 1 52  VAL 52  52  52  VAL VAL A . n 
A 1 53  ALA 53  53  53  ALA ALA A . n 
A 1 54  ARG 54  54  54  ARG ARG A . n 
A 1 55  VAL 55  55  55  VAL VAL A . n 
A 1 56  ALA 56  56  56  ALA ALA A . n 
A 1 57  ALA 57  57  57  ALA ALA A . n 
A 1 58  GLY 58  58  58  GLY GLY A . n 
A 1 59  LEU 59  59  59  LEU LEU A . n 
A 1 60  GLN 60  60  60  GLN GLN A . n 
A 1 61  ILE 61  61  61  ILE ILE A . n 
A 1 62  LYS 62  62  62  LYS LYS A . n 
A 1 63  ASN 63  63  63  ASN ASN A . n 
A 1 64  SER 64  64  64  SER SER A . n 
A 1 65  LEU 65  65  65  LEU LEU A . n 
A 1 66  THR 66  66  66  THR THR A . n 
A 1 67  SER 67  67  67  SER SER A . n 
A 1 68  LYS 68  68  68  LYS LYS A . n 
A 1 69  ASP 69  69  69  ASP ASP A . n 
A 1 70  PRO 70  70  70  PRO PRO A . n 
A 1 71  ASP 71  71  71  ASP ASP A . n 
A 1 72  ILE 72  72  72  ILE ILE A . n 
A 1 73  LYS 73  73  73  LYS LYS A . n 
A 1 74  ALA 74  74  74  ALA ALA A . n 
A 1 75  GLN 75  75  75  GLN GLN A . n 
A 1 76  TYR 76  76  76  TYR TYR A . n 
A 1 77  GLN 77  77  77  GLN GLN A . n 
A 1 78  GLN 78  78  78  GLN GLN A . n 
A 1 79  ARG 79  79  79  ARG ARG A . n 
A 1 80  TRP 80  80  80  TRP TRP A . n 
A 1 81  LEU 81  81  81  LEU LEU A . n 
A 1 82  ALA 82  82  82  ALA ALA A . n 
A 1 83  ILE 83  83  83  ILE ILE A . n 
A 1 84  ASP 84  84  84  ASP ASP A . n 
A 1 85  ALA 85  85  85  ALA ALA A . n 
A 1 86  ASN 86  86  86  ASN ASN A . n 
A 1 87  ALA 87  87  87  ALA ALA A . n 
A 1 88  ARG 88  88  88  ARG ARG A . n 
A 1 89  ARG 89  89  89  ARG ARG A . n 
A 1 90  GLU 90  90  90  GLU GLU A . n 
A 1 91  VAL 91  91  91  VAL VAL A . n 
A 1 92  LYS 92  92  92  LYS LYS A . n 
A 1 93  ASN 93  93  93  ASN ASN A . n 
A 1 94  TYR 94  94  94  TYR TYR A . n 
A 1 95  VAL 95  95  95  VAL VAL A . n 
A 1 96  LEU 96  96  96  LEU LEU A . n 
A 1 97  HIS 97  97  97  HIS HIS A . n 
A 1 98  THR 98  98  98  THR THR A . n 
A 1 99  LEU 99  99  99  LEU LEU A . n 
A 1 100 GLY 100 100 100 GLY GLY A . n 
A 1 101 THR 101 101 101 THR THR A . n 
A 1 102 GLU 102 102 102 GLU GLU A . n 
A 1 103 THR 103 103 103 THR THR A . n 
A 1 104 TYR 104 104 104 TYR TYR A . n 
A 1 105 ARG 105 105 105 ARG ARG A . n 
A 1 106 PRO 106 106 106 PRO PRO A . n 
A 1 107 SER 107 107 107 SER SER A . n 
A 1 108 SER 108 108 108 SER SER A . n 
A 1 109 ALA 109 109 109 ALA ALA A . n 
A 1 110 SER 110 110 110 SER SER A . n 
A 1 111 GLN 111 111 111 GLN GLN A . n 
A 1 112 CYS 112 112 112 CYS CYS A . n 
A 1 113 VAL 113 113 113 VAL VAL A . n 
A 1 114 ALA 114 114 114 ALA ALA A . n 
A 1 115 GLY 115 115 115 GLY GLY A . n 
A 1 116 ILE 116 116 116 ILE ILE A . n 
A 1 117 ALA 117 117 117 ALA ALA A . n 
A 1 118 CYS 118 118 118 CYS CYS A . n 
A 1 119 ALA 119 119 119 ALA ALA A . n 
A 1 120 GLU 120 120 120 GLU GLU A . n 
A 1 121 ILE 121 121 121 ILE ILE A . n 
A 1 122 PRO 122 122 122 PRO PRO A . n 
A 1 123 VAL 123 123 123 VAL VAL A . n 
A 1 124 ASN 124 124 124 ASN ASN A . n 
A 1 125 GLN 125 125 125 GLN GLN A . n 
A 1 126 TRP 126 126 126 TRP TRP A . n 
A 1 127 PRO 127 127 127 PRO PRO A . n 
A 1 128 GLU 128 128 128 GLU GLU A . n 
A 1 129 LEU 129 129 129 LEU LEU A . n 
A 1 130 ILE 130 130 130 ILE ILE A . n 
A 1 131 PRO 131 131 131 PRO PRO A . n 
A 1 132 GLN 132 132 132 GLN GLN A . n 
A 1 133 LEU 133 133 133 LEU LEU A . n 
A 1 134 VAL 134 134 134 VAL VAL A . n 
A 1 135 ALA 135 135 135 ALA ALA A . n 
A 1 136 ASN 136 136 136 ASN ASN A . n 
A 1 137 VAL 137 137 137 VAL VAL A . n 
A 1 138 THR 138 138 138 THR THR A . n 
A 1 139 ASN 139 139 139 ASN ASN A . n 
A 1 140 PRO 140 140 140 PRO PRO A . n 
A 1 141 ASN 141 141 141 ASN ASN A . n 
A 1 142 SER 142 142 142 SER SER A . n 
A 1 143 THR 143 143 143 THR THR A . n 
A 1 144 GLU 144 144 144 GLU GLU A . n 
A 1 145 HIS 145 145 145 HIS HIS A . n 
A 1 146 MET 146 146 146 MET MET A . n 
A 1 147 LYS 147 147 147 LYS LYS A . n 
A 1 148 GLU 148 148 148 GLU GLU A . n 
A 1 149 SER 149 149 149 SER SER A . n 
A 1 150 THR 150 150 150 THR THR A . n 
A 1 151 LEU 151 151 151 LEU LEU A . n 
A 1 152 GLU 152 152 152 GLU GLU A . n 
A 1 153 ALA 153 153 153 ALA ALA A . n 
A 1 154 ILE 154 154 154 ILE ILE A . n 
A 1 155 GLY 155 155 155 GLY GLY A . n 
A 1 156 TYR 156 156 156 TYR TYR A . n 
A 1 157 ILE 157 157 157 ILE ILE A . n 
A 1 158 CYS 158 158 158 CYS CYS A . n 
A 1 159 GLN 159 159 159 GLN GLN A . n 
A 1 160 ASP 160 160 160 ASP ASP A . n 
A 1 161 ILE 161 161 161 ILE ILE A . n 
A 1 162 ASP 162 162 162 ASP ASP A . n 
A 1 163 PRO 163 163 163 PRO PRO A . n 
A 1 164 GLU 164 164 164 GLU GLU A . n 
A 1 165 GLN 165 165 165 GLN GLN A . n 
A 1 166 LEU 166 166 166 LEU LEU A . n 
A 1 167 GLN 167 167 167 GLN GLN A . n 
A 1 168 ASP 168 168 168 ASP ASP A . n 
A 1 169 LYS 169 169 169 LYS LYS A . n 
A 1 170 SER 170 170 170 SER SER A . n 
A 1 171 ASN 171 171 171 ASN ASN A . n 
A 1 172 GLU 172 172 172 GLU GLU A . n 
A 1 173 ILE 173 173 173 ILE ILE A . n 
A 1 174 LEU 174 174 174 LEU LEU A . n 
A 1 175 THR 175 175 175 THR THR A . n 
A 1 176 ALA 176 176 176 ALA ALA A . n 
A 1 177 ILE 177 177 177 ILE ILE A . n 
A 1 178 ILE 178 178 178 ILE ILE A . n 
A 1 179 GLN 179 179 179 GLN GLN A . n 
A 1 180 GLY 180 180 180 GLY GLY A . n 
A 1 181 MET 181 181 181 MET MET A . n 
A 1 182 ARG 182 182 182 ARG ARG A . n 
A 1 183 LYS 183 183 183 LYS LYS A . n 
A 1 184 GLU 184 184 184 GLU GLU A . n 
A 1 185 GLU 185 185 185 GLU GLU A . n 
A 1 186 PRO 186 186 186 PRO PRO A . n 
A 1 187 SER 187 187 187 SER SER A . n 
A 1 188 ASN 188 188 188 ASN ASN A . n 
A 1 189 ASN 189 189 189 ASN ASN A . n 
A 1 190 VAL 190 190 190 VAL VAL A . n 
A 1 191 LYS 191 191 191 LYS LYS A . n 
A 1 192 LEU 192 192 192 LEU LEU A . n 
A 1 193 ALA 193 193 193 ALA ALA A . n 
A 1 194 ALA 194 194 194 ALA ALA A . n 
A 1 195 THR 195 195 195 THR THR A . n 
A 1 196 ASN 196 196 196 ASN ASN A . n 
A 1 197 ALA 197 197 197 ALA ALA A . n 
A 1 198 LEU 198 198 198 LEU LEU A . n 
A 1 199 LEU 199 199 199 LEU LEU A . n 
A 1 200 ASN 200 200 200 ASN ASN A . n 
A 1 201 SER 201 201 201 SER SER A . n 
A 1 202 LEU 202 202 202 LEU LEU A . n 
A 1 203 GLU 203 203 203 GLU GLU A . n 
A 1 204 PHE 204 204 204 PHE PHE A . n 
A 1 205 THR 205 205 205 THR THR A . n 
A 1 206 LYS 206 206 206 LYS LYS A . n 
A 1 207 ALA 207 207 207 ALA ALA A . n 
A 1 208 ASN 208 208 208 ASN ASN A . n 
A 1 209 PHE 209 209 209 PHE PHE A . n 
A 1 210 ASP 210 210 210 ASP ASP A . n 
A 1 211 LYS 211 211 211 LYS LYS A . n 
A 1 212 GLU 212 212 212 GLU GLU A . n 
A 1 213 SER 213 213 213 SER SER A . n 
A 1 214 GLU 214 214 214 GLU GLU A . n 
A 1 215 ARG 215 215 215 ARG ARG A . n 
A 1 216 HIS 216 216 216 HIS HIS A . n 
A 1 217 PHE 217 217 217 PHE PHE A . n 
A 1 218 ILE 218 218 218 ILE ILE A . n 
A 1 219 MET 219 219 219 MET MET A . n 
A 1 220 GLN 220 220 220 GLN GLN A . n 
A 1 221 VAL 221 221 221 VAL VAL A . n 
A 1 222 VAL 222 222 222 VAL VAL A . n 
A 1 223 CYS 223 223 223 CYS CYS A . n 
A 1 224 GLU 224 224 224 GLU GLU A . n 
A 1 225 ALA 225 225 225 ALA ALA A . n 
A 1 226 THR 226 226 226 THR THR A . n 
A 1 227 GLN 227 227 227 GLN GLN A . n 
A 1 228 CYS 228 228 228 CYS CYS A . n 
A 1 229 PRO 229 229 229 PRO PRO A . n 
A 1 230 ASP 230 230 230 ASP ASP A . n 
A 1 231 THR 231 231 231 THR THR A . n 
A 1 232 ARG 232 232 232 ARG ARG A . n 
A 1 233 VAL 233 233 233 VAL VAL A . n 
A 1 234 ARG 234 234 234 ARG ARG A . n 
A 1 235 VAL 235 235 235 VAL VAL A . n 
A 1 236 ALA 236 236 236 ALA ALA A . n 
A 1 237 ALA 237 237 237 ALA ALA A . n 
A 1 238 LEU 238 238 238 LEU LEU A . n 
A 1 239 GLN 239 239 239 GLN GLN A . n 
A 1 240 ASN 240 240 240 ASN ASN A . n 
A 1 241 LEU 241 241 241 LEU LEU A . n 
A 1 242 VAL 242 242 242 VAL VAL A . n 
A 1 243 LYS 243 243 243 LYS LYS A . n 
A 1 244 ILE 244 244 244 ILE ILE A . n 
A 1 245 MET 245 245 245 MET MET A . n 
A 1 246 SER 246 246 246 SER SER A . n 
A 1 247 LEU 247 247 247 LEU LEU A . n 
A 1 248 TYR 248 248 248 TYR TYR A . n 
A 1 249 TYR 249 249 249 TYR TYR A . n 
A 1 250 GLN 250 250 250 GLN GLN A . n 
A 1 251 TYR 251 251 251 TYR TYR A . n 
A 1 252 MET 252 252 252 MET MET A . n 
A 1 253 GLU 253 253 253 GLU GLU A . n 
A 1 254 THR 254 254 254 THR THR A . n 
A 1 255 TYR 255 255 255 TYR TYR A . n 
A 1 256 MET 256 256 256 MET MET A . n 
A 1 257 GLY 257 257 257 GLY GLY A . n 
A 1 258 PRO 258 258 258 PRO PRO A . n 
A 1 259 ALA 259 259 259 ALA ALA A . n 
A 1 260 LEU 260 260 260 LEU LEU A . n 
A 1 261 PHE 261 261 261 PHE PHE A . n 
A 1 262 ALA 262 262 262 ALA ALA A . n 
A 1 263 ILE 263 263 263 ILE ILE A . n 
A 1 264 THR 264 264 264 THR THR A . n 
A 1 265 ILE 265 265 265 ILE ILE A . n 
A 1 266 GLU 266 266 266 GLU GLU A . n 
A 1 267 ALA 267 267 267 ALA ALA A . n 
A 1 268 MET 268 268 268 MET MET A . n 
A 1 269 LYS 269 269 269 LYS LYS A . n 
A 1 270 SER 270 270 270 SER SER A . n 
A 1 271 ASP 271 271 271 ASP ASP A . n 
A 1 272 ILE 272 272 272 ILE ILE A . n 
A 1 273 ASP 273 273 273 ASP ASP A . n 
A 1 274 GLU 274 274 274 GLU GLU A . n 
A 1 275 VAL 275 275 275 VAL VAL A . n 
A 1 276 ALA 276 276 276 ALA ALA A . n 
A 1 277 LEU 277 277 277 LEU LEU A . n 
A 1 278 GLN 278 278 278 GLN GLN A . n 
A 1 279 GLY 279 279 279 GLY GLY A . n 
A 1 280 ILE 280 280 280 ILE ILE A . n 
A 1 281 GLU 281 281 281 GLU GLU A . n 
A 1 282 PHE 282 282 282 PHE PHE A . n 
A 1 283 TRP 283 283 283 TRP TRP A . n 
A 1 284 SER 284 284 284 SER SER A . n 
A 1 285 ASN 285 285 285 ASN ASN A . n 
A 1 286 VAL 286 286 286 VAL VAL A . n 
A 1 287 CYS 287 287 287 CYS CYS A . n 
A 1 288 ASP 288 288 288 ASP ASP A . n 
A 1 289 GLU 289 289 289 GLU GLU A . n 
A 1 290 GLU 290 290 290 GLU GLU A . n 
A 1 291 MET 291 291 291 MET MET A . n 
A 1 292 ASP 292 292 292 ASP ASP A . n 
A 1 293 LEU 293 293 293 LEU LEU A . n 
A 1 294 ALA 294 294 294 ALA ALA A . n 
A 1 295 ILE 295 295 295 ILE ILE A . n 
A 1 296 GLU 296 296 296 GLU GLU A . n 
A 1 297 ALA 297 297 297 ALA ALA A . n 
A 1 298 SER 298 298 298 SER SER A . n 
A 1 299 GLU 299 299 299 GLU GLU A . n 
A 1 300 ALA 300 300 300 ALA ALA A . n 
A 1 301 ALA 301 301 301 ALA ALA A . n 
A 1 302 GLU 302 302 302 GLU GLU A . n 
A 1 303 GLN 303 303 303 GLN GLN A . n 
A 1 304 GLY 304 304 304 GLY GLY A . n 
A 1 305 ARG 305 305 305 ARG ARG A . n 
A 1 306 PRO 306 306 306 PRO PRO A . n 
A 1 307 PRO 307 307 307 PRO PRO A . n 
A 1 308 GLU 308 308 308 GLU GLU A . n 
A 1 309 HIS 309 309 309 HIS HIS A . n 
A 1 310 THR 310 310 310 THR THR A . n 
A 1 311 SER 311 311 311 SER SER A . n 
A 1 312 LYS 312 312 312 LYS LYS A . n 
A 1 313 PHE 313 313 313 PHE PHE A . n 
A 1 314 TYR 314 314 314 TYR TYR A . n 
A 1 315 ALA 315 315 315 ALA ALA A . n 
A 1 316 LYS 316 316 316 LYS LYS A . n 
A 1 317 GLY 317 317 317 GLY GLY A . n 
A 1 318 ALA 318 318 318 ALA ALA A . n 
A 1 319 LEU 319 319 319 LEU LEU A . n 
A 1 320 GLN 320 320 320 GLN GLN A . n 
A 1 321 TYR 321 321 321 TYR TYR A . n 
A 1 322 LEU 322 322 322 LEU LEU A . n 
A 1 323 VAL 323 323 323 VAL VAL A . n 
A 1 324 PRO 324 324 324 PRO PRO A . n 
A 1 325 ILE 325 325 325 ILE ILE A . n 
A 1 326 LEU 326 326 326 LEU LEU A . n 
A 1 327 THR 327 327 327 THR THR A . n 
A 1 328 GLN 328 328 328 GLN GLN A . n 
A 1 329 THR 329 329 329 THR THR A . n 
A 1 330 LEU 330 330 330 LEU LEU A . n 
A 1 331 THR 331 331 331 THR THR A . n 
A 1 332 LYS 332 332 332 LYS LYS A . n 
A 1 333 GLN 333 333 333 GLN GLN A . n 
A 1 334 ASP 334 334 334 ASP ASP A . n 
A 1 335 GLU 335 335 335 GLU GLU A . n 
A 1 336 ASN 336 336 336 ASN ASN A . n 
A 1 337 ASP 337 337 337 ASP ASP A . n 
A 1 338 ASP 338 338 338 ASP ASP A . n 
A 1 339 ASP 339 339 339 ASP ASP A . n 
A 1 340 ASP 340 340 340 ASP ASP A . n 
A 1 341 ASP 341 341 341 ASP ASP A . n 
A 1 342 TRP 342 342 342 TRP TRP A . n 
A 1 343 ASN 343 343 343 ASN ASN A . n 
A 1 344 PRO 344 344 344 PRO PRO A . n 
A 1 345 CYS 345 345 345 CYS CYS A . n 
A 1 346 LYS 346 346 346 LYS LYS A . n 
A 1 347 ALA 347 347 347 ALA ALA A . n 
A 1 348 ALA 348 348 348 ALA ALA A . n 
A 1 349 GLY 349 349 349 GLY GLY A . n 
A 1 350 VAL 350 350 350 VAL VAL A . n 
A 1 351 CYS 351 351 351 CYS CYS A . n 
A 1 352 LEU 352 352 352 LEU LEU A . n 
A 1 353 MET 353 353 353 MET MET A . n 
A 1 354 LEU 354 354 354 LEU LEU A . n 
A 1 355 LEU 355 355 355 LEU LEU A . n 
A 1 356 ALA 356 356 356 ALA ALA A . n 
A 1 357 THR 357 357 357 THR THR A . n 
A 1 358 CYS 358 358 358 CYS CYS A . n 
A 1 359 CYS 359 359 359 CYS CYS A . n 
A 1 360 GLU 360 360 360 GLU GLU A . n 
A 1 361 ASP 361 361 361 ASP ASP A . n 
A 1 362 ASP 362 362 362 ASP ASP A . n 
A 1 363 ILE 363 363 363 ILE ILE A . n 
A 1 364 VAL 364 364 364 VAL VAL A . n 
A 1 365 PRO 365 365 365 PRO PRO A . n 
A 1 366 HIS 366 366 366 HIS HIS A . n 
A 1 367 VAL 367 367 367 VAL VAL A . n 
A 1 368 LEU 368 368 368 LEU LEU A . n 
A 1 369 PRO 369 369 369 PRO PRO A . n 
A 1 370 PHE 370 370 370 PHE PHE A . n 
A 1 371 ILE 371 371 371 ILE ILE A . n 
A 1 372 LYS 372 372 372 LYS LYS A . n 
A 1 373 GLU 373 373 373 GLU GLU A . n 
A 1 374 HIS 374 374 374 HIS HIS A . n 
A 1 375 ILE 375 375 375 ILE ILE A . n 
A 1 376 LYS 376 376 376 LYS LYS A . n 
A 1 377 ASN 377 377 377 ASN ASN A . n 
A 1 378 PRO 378 378 378 PRO PRO A . n 
A 1 379 ASP 379 379 379 ASP ASP A . n 
A 1 380 TRP 380 380 380 TRP TRP A . n 
A 1 381 ARG 381 381 381 ARG ARG A . n 
A 1 382 TYR 382 382 382 TYR TYR A . n 
A 1 383 ARG 383 383 383 ARG ARG A . n 
A 1 384 ASP 384 384 384 ASP ASP A . n 
A 1 385 ALA 385 385 385 ALA ALA A . n 
A 1 386 ALA 386 386 386 ALA ALA A . n 
A 1 387 VAL 387 387 387 VAL VAL A . n 
A 1 388 MET 388 388 388 MET MET A . n 
A 1 389 ALA 389 389 389 ALA ALA A . n 
A 1 390 PHE 390 390 390 PHE PHE A . n 
A 1 391 GLY 391 391 391 GLY GLY A . n 
A 1 392 CYS 392 392 392 CYS CYS A . n 
A 1 393 ILE 393 393 393 ILE ILE A . n 
A 1 394 LEU 394 394 394 LEU LEU A . n 
A 1 395 GLU 395 395 395 GLU GLU A . n 
A 1 396 GLY 396 396 396 GLY GLY A . n 
A 1 397 PRO 397 397 397 PRO PRO A . n 
A 1 398 GLU 398 398 398 GLU GLU A . n 
A 1 399 PRO 399 399 399 PRO PRO A . n 
A 1 400 SER 400 400 400 SER SER A . n 
A 1 401 GLN 401 401 401 GLN GLN A . n 
A 1 402 LEU 402 402 402 LEU LEU A . n 
A 1 403 LYS 403 403 403 LYS LYS A . n 
A 1 404 PRO 404 404 404 PRO PRO A . n 
A 1 405 LEU 405 405 405 LEU LEU A . n 
A 1 406 VAL 406 406 406 VAL VAL A . n 
A 1 407 ILE 407 407 407 ILE ILE A . n 
A 1 408 GLN 408 408 408 GLN GLN A . n 
A 1 409 ALA 409 409 409 ALA ALA A . n 
A 1 410 MET 410 410 410 MET MET A . n 
A 1 411 PRO 411 411 411 PRO PRO A . n 
A 1 412 THR 412 412 412 THR THR A . n 
A 1 413 LEU 413 413 413 LEU LEU A . n 
A 1 414 ILE 414 414 414 ILE ILE A . n 
A 1 415 GLU 415 415 415 GLU GLU A . n 
A 1 416 LEU 416 416 416 LEU LEU A . n 
A 1 417 MET 417 417 417 MET MET A . n 
A 1 418 LYS 418 418 418 LYS LYS A . n 
A 1 419 ASP 419 419 419 ASP ASP A . n 
A 1 420 PRO 420 420 420 PRO PRO A . n 
A 1 421 SER 421 421 421 SER SER A . n 
A 1 422 VAL 422 422 422 VAL VAL A . n 
A 1 423 VAL 423 423 423 VAL VAL A . n 
A 1 424 VAL 424 424 424 VAL VAL A . n 
A 1 425 ARG 425 425 425 ARG ARG A . n 
A 1 426 ASP 426 426 426 ASP ASP A . n 
A 1 427 THR 427 427 427 THR THR A . n 
A 1 428 ALA 428 428 428 ALA ALA A . n 
A 1 429 ALA 429 429 429 ALA ALA A . n 
A 1 430 TRP 430 430 430 TRP TRP A . n 
A 1 431 THR 431 431 431 THR THR A . n 
A 1 432 VAL 432 432 432 VAL VAL A . n 
A 1 433 GLY 433 433 433 GLY GLY A . n 
A 1 434 ARG 434 434 434 ARG ARG A . n 
A 1 435 ILE 435 435 435 ILE ILE A . n 
A 1 436 CYS 436 436 436 CYS CYS A . n 
A 1 437 GLU 437 437 437 GLU GLU A . n 
A 1 438 LEU 438 438 438 LEU LEU A . n 
A 1 439 LEU 439 439 439 LEU LEU A . n 
A 1 440 PRO 440 440 440 PRO PRO A . n 
A 1 441 GLU 441 441 441 GLU GLU A . n 
A 1 442 ALA 442 442 442 ALA ALA A . n 
A 1 443 ALA 443 443 443 ALA ALA A . n 
A 1 444 ILE 444 444 444 ILE ILE A . n 
A 1 445 ASN 445 445 445 ASN ASN A . n 
A 1 446 ASP 446 446 446 ASP ASP A . n 
A 1 447 VAL 447 447 447 VAL VAL A . n 
A 1 448 TYR 448 448 448 TYR TYR A . n 
A 1 449 LEU 449 449 449 LEU LEU A . n 
A 1 450 ALA 450 450 450 ALA ALA A . n 
A 1 451 PRO 451 451 451 PRO PRO A . n 
A 1 452 LEU 452 452 452 LEU LEU A . n 
A 1 453 LEU 453 453 453 LEU LEU A . n 
A 1 454 GLN 454 454 454 GLN GLN A . n 
A 1 455 CYS 455 455 455 CYS CYS A . n 
A 1 456 LEU 456 456 456 LEU LEU A . n 
A 1 457 ILE 457 457 457 ILE ILE A . n 
A 1 458 GLU 458 458 458 GLU GLU A . n 
A 1 459 GLY 459 459 459 GLY GLY A . n 
A 1 460 LEU 460 460 460 LEU LEU A . n 
A 1 461 SER 461 461 461 SER SER A . n 
A 1 462 ALA 462 462 462 ALA ALA A . n 
A 1 463 GLU 463 463 463 GLU GLU A . n 
A 1 464 PRO 464 464 464 PRO PRO A . n 
A 1 465 ARG 465 465 465 ARG ARG A . n 
A 1 466 VAL 466 466 466 VAL VAL A . n 
A 1 467 ALA 467 467 467 ALA ALA A . n 
A 1 468 SER 468 468 468 SER SER A . n 
A 1 469 ASN 469 469 469 ASN ASN A . n 
A 1 470 VAL 470 470 470 VAL VAL A . n 
A 1 471 CYS 471 471 471 CYS CYS A . n 
A 1 472 TRP 472 472 472 TRP TRP A . n 
A 1 473 ALA 473 473 473 ALA ALA A . n 
A 1 474 PHE 474 474 474 PHE PHE A . n 
A 1 475 SER 475 475 475 SER SER A . n 
A 1 476 SER 476 476 476 SER SER A . n 
A 1 477 LEU 477 477 477 LEU LEU A . n 
A 1 478 ALA 478 478 478 ALA ALA A . n 
A 1 479 GLU 479 479 479 GLU GLU A . n 
A 1 480 ALA 480 480 480 ALA ALA A . n 
A 1 481 ALA 481 481 481 ALA ALA A . n 
A 1 482 TYR 482 482 482 TYR TYR A . n 
A 1 483 GLU 483 483 483 GLU GLU A . n 
A 1 484 ALA 484 484 484 ALA ALA A . n 
A 1 485 ALA 485 485 485 ALA ALA A . n 
A 1 486 ASP 486 486 486 ASP ASP A . n 
A 1 487 VAL 487 487 487 VAL VAL A . n 
A 1 488 ALA 488 488 488 ALA ALA A . n 
A 1 489 ASP 489 489 489 ASP ASP A . n 
A 1 490 ASP 490 490 490 ASP ASP A . n 
A 1 491 GLN 491 491 491 GLN GLN A . n 
A 1 492 GLU 492 492 492 GLU GLU A . n 
A 1 493 GLU 493 493 493 GLU GLU A . n 
A 1 494 PRO 494 494 494 PRO PRO A . n 
A 1 495 ALA 495 495 495 ALA ALA A . n 
A 1 496 THR 496 496 496 THR THR A . n 
A 1 497 TYR 497 497 497 TYR TYR A . n 
A 1 498 CYS 498 498 498 CYS CYS A . n 
A 1 499 LEU 499 499 499 LEU LEU A . n 
A 1 500 SER 500 500 500 SER SER A . n 
A 1 501 SER 501 501 501 SER SER A . n 
A 1 502 SER 502 502 502 SER SER A . n 
A 1 503 PHE 503 503 503 PHE PHE A . n 
A 1 504 GLU 504 504 504 GLU GLU A . n 
A 1 505 LEU 505 505 505 LEU LEU A . n 
A 1 506 ILE 506 506 506 ILE ILE A . n 
A 1 507 VAL 507 507 507 VAL VAL A . n 
A 1 508 GLN 508 508 508 GLN GLN A . n 
A 1 509 LYS 509 509 509 LYS LYS A . n 
A 1 510 LEU 510 510 510 LEU LEU A . n 
A 1 511 LEU 511 511 511 LEU LEU A . n 
A 1 512 GLU 512 512 512 GLU GLU A . n 
A 1 513 THR 513 513 513 THR THR A . n 
A 1 514 THR 514 514 514 THR THR A . n 
A 1 515 ASP 515 515 515 ASP ASP A . n 
A 1 516 ARG 516 516 516 ARG ARG A . n 
A 1 517 PRO 517 517 517 PRO PRO A . n 
A 1 518 ASP 518 518 518 ASP ASP A . n 
A 1 519 GLY 519 519 519 GLY GLY A . n 
A 1 520 HIS 520 520 520 HIS HIS A . n 
A 1 521 GLN 521 521 521 GLN GLN A . n 
A 1 522 ASN 522 522 522 ASN ASN A . n 
A 1 523 ASN 523 523 523 ASN ASN A . n 
A 1 524 LEU 524 524 524 LEU LEU A . n 
A 1 525 ARG 525 525 525 ARG ARG A . n 
A 1 526 SER 526 526 526 SER SER A . n 
A 1 527 SER 527 527 527 SER SER A . n 
A 1 528 ALA 528 528 528 ALA ALA A . n 
A 1 529 TYR 529 529 529 TYR TYR A . n 
A 1 530 GLU 530 530 530 GLU GLU A . n 
A 1 531 SER 531 531 531 SER SER A . n 
A 1 532 LEU 532 532 532 LEU LEU A . n 
A 1 533 MET 533 533 533 MET MET A . n 
A 1 534 GLU 534 534 534 GLU GLU A . n 
A 1 535 ILE 535 535 535 ILE ILE A . n 
A 1 536 VAL 536 536 536 VAL VAL A . n 
A 1 537 LYS 537 537 537 LYS LYS A . n 
A 1 538 ASN 538 538 538 ASN ASN A . n 
A 1 539 SER 539 539 539 SER SER A . n 
A 1 540 ALA 540 540 540 ALA ALA A . n 
A 1 541 LYS 541 541 541 LYS LYS A . n 
A 1 542 ASP 542 542 542 ASP ASP A . n 
A 1 543 CYS 543 543 543 CYS CYS A . n 
A 1 544 TYR 544 544 544 TYR TYR A . n 
A 1 545 PRO 545 545 545 PRO PRO A . n 
A 1 546 ALA 546 546 546 ALA ALA A . n 
A 1 547 VAL 547 547 547 VAL VAL A . n 
A 1 548 GLN 548 548 548 GLN GLN A . n 
A 1 549 LYS 549 549 549 LYS LYS A . n 
A 1 550 THR 550 550 550 THR THR A . n 
A 1 551 THR 551 551 551 THR THR A . n 
A 1 552 LEU 552 552 552 LEU LEU A . n 
A 1 553 VAL 553 553 553 VAL VAL A . n 
A 1 554 ILE 554 554 554 ILE ILE A . n 
A 1 555 MET 555 555 555 MET MET A . n 
A 1 556 GLU 556 556 556 GLU GLU A . n 
A 1 557 ARG 557 557 557 ARG ARG A . n 
A 1 558 LEU 558 558 558 LEU LEU A . n 
A 1 559 GLN 559 559 559 GLN GLN A . n 
A 1 560 GLN 560 560 560 GLN GLN A . n 
A 1 561 VAL 561 561 561 VAL VAL A . n 
A 1 562 LEU 562 562 562 LEU LEU A . n 
A 1 563 GLN 563 563 563 GLN GLN A . n 
A 1 564 MET 564 564 564 MET MET A . n 
A 1 565 GLU 565 565 565 GLU GLU A . n 
A 1 566 SER 566 566 566 SER SER A . n 
A 1 567 HIS 567 567 567 HIS HIS A . n 
A 1 568 ILE 568 568 568 ILE ILE A . n 
A 1 569 GLN 569 569 569 GLN GLN A . n 
A 1 570 SER 570 570 570 SER SER A . n 
A 1 571 THR 571 571 571 THR THR A . n 
A 1 572 SER 572 572 572 SER SER A . n 
A 1 573 ASP 573 573 573 ASP ASP A . n 
A 1 574 ARG 574 574 574 ARG ARG A . n 
A 1 575 ILE 575 575 575 ILE ILE A . n 
A 1 576 GLN 576 576 576 GLN GLN A . n 
A 1 577 PHE 577 577 577 PHE PHE A . n 
A 1 578 ASN 578 578 578 ASN ASN A . n 
A 1 579 ASP 579 579 579 ASP ASP A . n 
A 1 580 LEU 580 580 580 LEU LEU A . n 
A 1 581 GLN 581 581 581 GLN GLN A . n 
A 1 582 SER 582 582 582 SER SER A . n 
A 1 583 LEU 583 583 583 LEU LEU A . n 
A 1 584 LEU 584 584 584 LEU LEU A . n 
A 1 585 CYS 585 585 585 CYS CYS A . n 
A 1 586 ALA 586 586 586 ALA ALA A . n 
A 1 587 THR 587 587 587 THR THR A . n 
A 1 588 LEU 588 588 588 LEU LEU A . n 
A 1 589 GLN 589 589 589 GLN GLN A . n 
A 1 590 ASN 590 590 590 ASN ASN A . n 
A 1 591 VAL 591 591 591 VAL VAL A . n 
A 1 592 LEU 592 592 592 LEU LEU A . n 
A 1 593 ARG 593 593 593 ARG ARG A . n 
A 1 594 LYS 594 594 594 LYS LYS A . n 
A 1 595 VAL 595 595 595 VAL VAL A . n 
A 1 596 GLN 596 596 596 GLN GLN A . n 
A 1 597 HIS 597 597 597 HIS HIS A . n 
A 1 598 GLN 598 598 598 GLN GLN A . n 
A 1 599 ASP 599 599 599 ASP ASP A . n 
A 1 600 ALA 600 600 600 ALA ALA A . n 
A 1 601 LEU 601 601 601 LEU LEU A . n 
A 1 602 GLN 602 602 602 GLN GLN A . n 
A 1 603 ILE 603 603 603 ILE ILE A . n 
A 1 604 SER 604 604 604 SER SER A . n 
A 1 605 ASP 605 605 605 ASP ASP A . n 
A 1 606 VAL 606 606 606 VAL VAL A . n 
A 1 607 VAL 607 607 607 VAL VAL A . n 
A 1 608 MET 608 608 608 MET MET A . n 
A 1 609 ALA 609 609 609 ALA ALA A . n 
A 1 610 SER 610 610 610 SER SER A . n 
A 1 611 LEU 611 611 611 LEU LEU A . n 
A 1 612 LEU 612 612 612 LEU LEU A . n 
A 1 613 ARG 613 613 613 ARG ARG A . n 
A 1 614 MET 614 614 614 MET MET A . n 
A 1 615 PHE 615 615 615 PHE PHE A . n 
A 1 616 GLN 616 616 616 GLN GLN A . n 
A 1 617 SER 617 617 617 SER SER A . n 
A 1 618 THR 618 618 618 THR THR A . n 
A 1 619 ALA 619 619 619 ALA ALA A . n 
A 1 620 GLY 620 620 620 GLY GLY A . n 
A 1 621 SER 621 621 621 SER SER A . n 
A 1 622 GLY 622 622 622 GLY GLY A . n 
A 1 623 GLY 623 623 623 GLY GLY A . n 
A 1 624 VAL 624 624 624 VAL VAL A . n 
A 1 625 GLN 625 625 625 GLN GLN A . n 
A 1 626 GLU 626 626 626 GLU GLU A . n 
A 1 627 ASP 627 627 627 ASP ASP A . n 
A 1 628 ALA 628 628 628 ALA ALA A . n 
A 1 629 LEU 629 629 629 LEU LEU A . n 
A 1 630 MET 630 630 630 MET MET A . n 
A 1 631 ALA 631 631 631 ALA ALA A . n 
A 1 632 VAL 632 632 632 VAL VAL A . n 
A 1 633 SER 633 633 633 SER SER A . n 
A 1 634 THR 634 634 634 THR THR A . n 
A 1 635 LEU 635 635 635 LEU LEU A . n 
A 1 636 VAL 636 636 636 VAL VAL A . n 
A 1 637 GLU 637 637 637 GLU GLU A . n 
A 1 638 VAL 638 638 638 VAL VAL A . n 
A 1 639 LEU 639 639 639 LEU LEU A . n 
A 1 640 GLY 640 640 640 GLY GLY A . n 
A 1 641 GLY 641 641 641 GLY GLY A . n 
A 1 642 GLU 642 642 642 GLU GLU A . n 
A 1 643 PHE 643 643 643 PHE PHE A . n 
A 1 644 LEU 644 644 644 LEU LEU A . n 
A 1 645 LYS 645 645 645 LYS LYS A . n 
A 1 646 TYR 646 646 646 TYR TYR A . n 
A 1 647 MET 647 647 647 MET MET A . n 
A 1 648 GLU 648 648 648 GLU GLU A . n 
A 1 649 ALA 649 649 649 ALA ALA A . n 
A 1 650 PHE 650 650 650 PHE PHE A . n 
A 1 651 LYS 651 651 651 LYS LYS A . n 
A 1 652 PRO 652 652 652 PRO PRO A . n 
A 1 653 PHE 653 653 653 PHE PHE A . n 
A 1 654 LEU 654 654 654 LEU LEU A . n 
A 1 655 GLY 655 655 655 GLY GLY A . n 
A 1 656 ILE 656 656 656 ILE ILE A . n 
A 1 657 GLY 657 657 657 GLY GLY A . n 
A 1 658 LEU 658 658 658 LEU LEU A . n 
A 1 659 LYS 659 659 659 LYS LYS A . n 
A 1 660 ASN 660 660 660 ASN ASN A . n 
A 1 661 TYR 661 661 661 TYR TYR A . n 
A 1 662 ALA 662 662 662 ALA ALA A . n 
A 1 663 GLU 663 663 663 GLU GLU A . n 
A 1 664 TYR 664 664 664 TYR TYR A . n 
A 1 665 GLN 665 665 665 GLN GLN A . n 
A 1 666 VAL 666 666 666 VAL VAL A . n 
A 1 667 CYS 667 667 667 CYS CYS A . n 
A 1 668 LEU 668 668 668 LEU LEU A . n 
A 1 669 ALA 669 669 669 ALA ALA A . n 
A 1 670 ALA 670 670 670 ALA ALA A . n 
A 1 671 VAL 671 671 671 VAL VAL A . n 
A 1 672 GLY 672 672 672 GLY GLY A . n 
A 1 673 LEU 673 673 673 LEU LEU A . n 
A 1 674 VAL 674 674 674 VAL VAL A . n 
A 1 675 GLY 675 675 675 GLY GLY A . n 
A 1 676 ASP 676 676 676 ASP ASP A . n 
A 1 677 LEU 677 677 677 LEU LEU A . n 
A 1 678 CYS 678 678 678 CYS CYS A . n 
A 1 679 ARG 679 679 679 ARG ARG A . n 
A 1 680 ALA 680 680 680 ALA ALA A . n 
A 1 681 LEU 681 681 681 LEU LEU A . n 
A 1 682 GLN 682 682 682 GLN GLN A . n 
A 1 683 SER 683 683 683 SER SER A . n 
A 1 684 ASN 684 684 684 ASN ASN A . n 
A 1 685 ILE 685 685 685 ILE ILE A . n 
A 1 686 ILE 686 686 686 ILE ILE A . n 
A 1 687 PRO 687 687 687 PRO PRO A . n 
A 1 688 PHE 688 688 688 PHE PHE A . n 
A 1 689 CYS 689 689 689 CYS CYS A . n 
A 1 690 ASP 690 690 690 ASP ASP A . n 
A 1 691 GLU 691 691 691 GLU GLU A . n 
A 1 692 VAL 692 692 692 VAL VAL A . n 
A 1 693 MET 693 693 693 MET MET A . n 
A 1 694 GLN 694 694 694 GLN GLN A . n 
A 1 695 LEU 695 695 695 LEU LEU A . n 
A 1 696 LEU 696 696 696 LEU LEU A . n 
A 1 697 LEU 697 697 697 LEU LEU A . n 
A 1 698 GLU 698 698 698 GLU GLU A . n 
A 1 699 ASN 699 699 699 ASN ASN A . n 
A 1 700 LEU 700 700 700 LEU LEU A . n 
A 1 701 GLY 701 701 701 GLY GLY A . n 
A 1 702 ASN 702 702 702 ASN ASN A . n 
A 1 703 GLU 703 703 703 GLU GLU A . n 
A 1 704 ASN 704 704 704 ASN ASN A . n 
A 1 705 VAL 705 705 705 VAL VAL A . n 
A 1 706 HIS 706 706 706 HIS HIS A . n 
A 1 707 ARG 707 707 707 ARG ARG A . n 
A 1 708 SER 708 708 708 SER SER A . n 
A 1 709 VAL 709 709 709 VAL VAL A . n 
A 1 710 LYS 710 710 710 LYS LYS A . n 
A 1 711 PRO 711 711 711 PRO PRO A . n 
A 1 712 GLN 712 712 712 GLN GLN A . n 
A 1 713 ILE 713 713 713 ILE ILE A . n 
A 1 714 LEU 714 714 714 LEU LEU A . n 
A 1 715 SER 715 715 715 SER SER A . n 
A 1 716 VAL 716 716 716 VAL VAL A . n 
A 1 717 PHE 717 717 717 PHE PHE A . n 
A 1 718 GLY 718 718 718 GLY GLY A . n 
A 1 719 ASP 719 719 719 ASP ASP A . n 
A 1 720 ILE 720 720 720 ILE ILE A . n 
A 1 721 ALA 721 721 721 ALA ALA A . n 
A 1 722 LEU 722 722 722 LEU LEU A . n 
A 1 723 ALA 723 723 723 ALA ALA A . n 
A 1 724 ILE 724 724 724 ILE ILE A . n 
A 1 725 GLY 725 725 725 GLY GLY A . n 
A 1 726 GLY 726 726 726 GLY GLY A . n 
A 1 727 GLU 727 727 727 GLU GLU A . n 
A 1 728 PHE 728 728 728 PHE PHE A . n 
A 1 729 LYS 729 729 729 LYS LYS A . n 
A 1 730 LYS 730 730 730 LYS LYS A . n 
A 1 731 TYR 731 731 731 TYR TYR A . n 
A 1 732 LEU 732 732 732 LEU LEU A . n 
A 1 733 GLU 733 733 733 GLU GLU A . n 
A 1 734 VAL 734 734 734 VAL VAL A . n 
A 1 735 VAL 735 735 735 VAL VAL A . n 
A 1 736 LEU 736 736 736 LEU LEU A . n 
A 1 737 ASN 737 737 737 ASN ASN A . n 
A 1 738 THR 738 738 738 THR THR A . n 
A 1 739 LEU 739 739 739 LEU LEU A . n 
A 1 740 GLN 740 740 740 GLN GLN A . n 
A 1 741 GLN 741 741 741 GLN GLN A . n 
A 1 742 ALA 742 742 742 ALA ALA A . n 
A 1 743 SER 743 743 743 SER SER A . n 
A 1 744 GLN 744 744 744 GLN GLN A . n 
A 1 745 ALA 745 745 745 ALA ALA A . n 
A 1 746 GLN 746 746 746 GLN GLN A . n 
A 1 747 VAL 747 747 747 VAL VAL A . n 
A 1 748 ASP 748 748 748 ASP ASP A . n 
A 1 749 LYS 749 749 749 LYS LYS A . n 
A 1 750 SER 750 750 750 SER SER A . n 
A 1 751 ASP 751 751 751 ASP ASP A . n 
A 1 752 TYR 752 752 752 TYR TYR A . n 
A 1 753 ASP 753 753 753 ASP ASP A . n 
A 1 754 MET 754 754 754 MET MET A . n 
A 1 755 VAL 755 755 755 VAL VAL A . n 
A 1 756 ASP 756 756 756 ASP ASP A . n 
A 1 757 TYR 757 757 757 TYR TYR A . n 
A 1 758 LEU 758 758 758 LEU LEU A . n 
A 1 759 ASN 759 759 759 ASN ASN A . n 
A 1 760 GLU 760 760 760 GLU GLU A . n 
A 1 761 LEU 761 761 761 LEU LEU A . n 
A 1 762 ARG 762 762 762 ARG ARG A . n 
A 1 763 GLU 763 763 763 GLU GLU A . n 
A 1 764 SER 764 764 764 SER SER A . n 
A 1 765 CYS 765 765 765 CYS CYS A . n 
A 1 766 LEU 766 766 766 LEU LEU A . n 
A 1 767 GLU 767 767 767 GLU GLU A . n 
A 1 768 ALA 768 768 768 ALA ALA A . n 
A 1 769 TYR 769 769 769 TYR TYR A . n 
A 1 770 THR 770 770 770 THR THR A . n 
A 1 771 GLY 771 771 771 GLY GLY A . n 
A 1 772 ILE 772 772 772 ILE ILE A . n 
A 1 773 VAL 773 773 773 VAL VAL A . n 
A 1 774 GLN 774 774 774 GLN GLN A . n 
A 1 775 GLY 775 775 775 GLY GLY A . n 
A 1 776 LEU 776 776 776 LEU LEU A . n 
A 1 777 LYS 777 777 777 LYS LYS A . n 
A 1 778 GLY 778 778 778 GLY GLY A . n 
A 1 779 ASP 779 779 779 ASP ASP A . n 
A 1 780 GLN 780 780 780 GLN GLN A . n 
A 1 781 GLU 781 781 781 GLU GLU A . n 
A 1 782 ASN 782 782 782 ASN ASN A . n 
A 1 783 VAL 783 783 783 VAL VAL A . n 
A 1 784 HIS 784 784 784 HIS HIS A . n 
A 1 785 PRO 785 785 785 PRO PRO A . n 
A 1 786 ASP 786 786 786 ASP ASP A . n 
A 1 787 VAL 787 787 787 VAL VAL A . n 
A 1 788 MET 788 788 788 MET MET A . n 
A 1 789 LEU 789 789 789 LEU LEU A . n 
A 1 790 VAL 790 790 790 VAL VAL A . n 
A 1 791 GLN 791 791 791 GLN GLN A . n 
A 1 792 PRO 792 792 792 PRO PRO A . n 
A 1 793 ARG 793 793 793 ARG ARG A . n 
A 1 794 VAL 794 794 794 VAL VAL A . n 
A 1 795 GLU 795 795 795 GLU GLU A . n 
A 1 796 PHE 796 796 796 PHE PHE A . n 
A 1 797 ILE 797 797 797 ILE ILE A . n 
A 1 798 LEU 798 798 798 LEU LEU A . n 
A 1 799 SER 799 799 799 SER SER A . n 
A 1 800 PHE 800 800 800 PHE PHE A . n 
A 1 801 ILE 801 801 801 ILE ILE A . n 
A 1 802 ASP 802 802 802 ASP ASP A . n 
A 1 803 HIS 803 803 803 HIS HIS A . n 
A 1 804 ILE 804 804 804 ILE ILE A . n 
A 1 805 ALA 805 805 805 ALA ALA A . n 
A 1 806 GLY 806 806 806 GLY GLY A . n 
A 1 807 ASP 807 807 807 ASP ASP A . n 
A 1 808 GLU 808 808 808 GLU GLU A . n 
A 1 809 ASP 809 809 809 ASP ASP A . n 
A 1 810 HIS 810 810 810 HIS HIS A . n 
A 1 811 THR 811 811 811 THR THR A . n 
A 1 812 ASP 812 812 812 ASP ASP A . n 
A 1 813 GLY 813 813 813 GLY GLY A . n 
A 1 814 VAL 814 814 814 VAL VAL A . n 
A 1 815 VAL 815 815 815 VAL VAL A . n 
A 1 816 ALA 816 816 816 ALA ALA A . n 
A 1 817 CYS 817 817 817 CYS CYS A . n 
A 1 818 ALA 818 818 818 ALA ALA A . n 
A 1 819 ALA 819 819 819 ALA ALA A . n 
A 1 820 GLY 820 820 820 GLY GLY A . n 
A 1 821 LEU 821 821 821 LEU LEU A . n 
A 1 822 ILE 822 822 822 ILE ILE A . n 
A 1 823 GLY 823 823 823 GLY GLY A . n 
A 1 824 ASP 824 824 824 ASP ASP A . n 
A 1 825 LEU 825 825 825 LEU LEU A . n 
A 1 826 CYS 826 826 826 CYS CYS A . n 
A 1 827 THR 827 827 827 THR THR A . n 
A 1 828 ALA 828 828 828 ALA ALA A . n 
A 1 829 PHE 829 829 829 PHE PHE A . n 
A 1 830 GLY 830 830 830 GLY GLY A . n 
A 1 831 LYS 831 831 831 LYS LYS A . n 
A 1 832 ASP 832 832 832 ASP ASP A . n 
A 1 833 VAL 833 833 833 VAL VAL A . n 
A 1 834 LEU 834 834 834 LEU LEU A . n 
A 1 835 LYS 835 835 835 LYS LYS A . n 
A 1 836 LEU 836 836 836 LEU LEU A . n 
A 1 837 VAL 837 837 837 VAL VAL A . n 
A 1 838 GLU 838 838 838 GLU GLU A . n 
A 1 839 ALA 839 839 839 ALA ALA A . n 
A 1 840 ARG 840 840 840 ARG ARG A . n 
A 1 841 PRO 841 841 841 PRO PRO A . n 
A 1 842 MET 842 842 842 MET MET A . n 
A 1 843 ILE 843 843 843 ILE ILE A . n 
A 1 844 HIS 844 844 844 HIS HIS A . n 
A 1 845 GLU 845 845 845 GLU GLU A . n 
A 1 846 LEU 846 846 846 LEU LEU A . n 
A 1 847 LEU 847 847 847 LEU LEU A . n 
A 1 848 THR 848 848 848 THR THR A . n 
A 1 849 GLU 849 849 849 GLU GLU A . n 
A 1 850 GLY 850 850 850 GLY GLY A . n 
A 1 851 ARG 851 851 851 ARG ARG A . n 
A 1 852 ARG 852 852 852 ARG ARG A . n 
A 1 853 SER 853 853 853 SER SER A . n 
A 1 854 LYS 854 854 854 LYS LYS A . n 
A 1 855 THR 855 855 855 THR THR A . n 
A 1 856 ASN 856 856 856 ASN ASN A . n 
A 1 857 LYS 857 857 857 LYS LYS A . n 
A 1 858 ALA 858 858 858 ALA ALA A . n 
A 1 859 LYS 859 859 859 LYS LYS A . n 
A 1 860 THR 860 860 860 THR THR A . n 
A 1 861 LEU 861 861 861 LEU LEU A . n 
A 1 862 ALA 862 862 862 ALA ALA A . n 
A 1 863 ARG 863 863 863 ARG ARG A . n 
A 1 864 TRP 864 864 864 TRP TRP A . n 
A 1 865 ALA 865 865 865 ALA ALA A . n 
A 1 866 THR 866 866 866 THR THR A . n 
A 1 867 LYS 867 867 867 LYS LYS A . n 
A 1 868 GLU 868 868 868 GLU GLU A . n 
A 1 869 LEU 869 869 869 LEU LEU A . n 
A 1 870 ARG 870 870 870 ARG ARG A . n 
A 1 871 LYS 871 871 871 LYS LYS A . n 
A 1 872 LEU 872 872 872 LEU LEU A . n 
A 1 873 LYS 873 873 873 LYS LYS A . n 
A 1 874 ASN 874 874 874 ASN ASN A . n 
A 1 875 GLN 875 875 875 GLN GLN A . n 
A 1 876 ALA 876 876 876 ALA ALA A . n 
B 2 1   ALA 1   11  11  ALA ALA B . n 
B 2 2   ALA 2   12  12  ALA ALA B . n 
B 2 3   ARG 3   13  13  ARG ARG B . n 
B 2 4   LEU 4   14  14  LEU LEU B . n 
B 2 5   HIS 5   15  15  HIS HIS B . n 
B 2 6   ARG 6   16  16  ARG ARG B . n 
B 2 7   PHE 7   17  17  PHE PHE B . n 
B 2 8   LYS 8   18  18  LYS LYS B . n 
B 2 9   ASN 9   19  19  ASN ASN B . n 
B 2 10  LYS 10  20  20  LYS LYS B . n 
B 2 11  GLY 11  21  21  GLY GLY B . n 
B 2 12  LYS 12  22  22  LYS LYS B . n 
B 2 13  ASP 13  23  23  ASP ASP B . n 
B 2 14  SER 14  24  24  SER SER B . n 
B 2 15  THR 15  25  25  THR THR B . n 
B 2 16  GLU 16  26  26  GLU GLU B . n 
B 2 17  MET 17  27  27  MET MET B . n 
B 2 18  ARG 18  28  28  ARG ARG B . n 
B 2 19  ARG 19  29  29  ARG ARG B . n 
B 2 20  ARG 20  30  30  ARG ARG B . n 
B 2 21  ARG 21  31  31  ARG ARG B . n 
B 2 22  ILE 22  32  32  ILE ILE B . n 
B 2 23  GLU 23  33  33  GLU GLU B . n 
B 2 24  VAL 24  34  34  VAL VAL B . n 
B 2 25  ASN 25  35  35  ASN ASN B . n 
B 2 26  VAL 26  36  36  VAL VAL B . n 
B 2 27  GLU 27  37  37  GLU GLU B . n 
B 2 28  LEU 28  38  38  LEU LEU B . n 
B 2 29  ARG 29  39  39  ARG ARG B . n 
B 2 30  LYS 30  40  40  LYS LYS B . n 
B 2 31  ALA 31  41  41  ALA ALA B . n 
B 2 32  LYS 32  42  42  LYS LYS B . n 
B 2 33  LYS 33  43  43  LYS LYS B . n 
B 2 34  ASP 34  44  44  ASP ASP B . n 
B 2 35  ASP 35  45  45  ASP ASP B . n 
B 2 36  GLN 36  46  46  GLN GLN B . n 
B 2 37  MET 37  47  47  MET MET B . n 
B 2 38  LEU 38  48  48  LEU LEU B . n 
B 2 39  LYS 39  49  49  LYS LYS B . n 
B 2 40  ARG 40  50  50  ARG ARG B . n 
B 2 41  ARG 41  51  51  ARG ARG B . n 
B 2 42  ASN 42  52  52  ASN ASN B . n 
B 2 43  VAL 43  53  53  VAL VAL B . n 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9B4Y 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9B4Y 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9B4Y 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 9B4Y 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.001  ? 7291 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.444  ? 9882 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 12.308 ? 2753 ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.035  ? 1147 ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.003  ? 1292 ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9B4Y 
_struct.title                        'Cryo-EM structure of importin alpha-1/beta bound to TDP-43' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9B4Y 
_struct_keywords.text            'Importins, TRANSPORT PROTEIN, TDP-43' 
_struct_keywords.pdbx_keywords   'TRANSPORT PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP IMB1_HUMAN Q14974 ? 1 
;MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQIKNSLTSKDPDIKAQYQQRW
LAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIACAEIPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQD
IDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIMQVVCEATQCPDTRVRVAALQN
LVKIMSLYYQYMETYMGPALFAITIEAMKSDIDEVALQGIEFWSNVCDEEMDLAIEASEAAEQGRPPEHTSKFYAKGALQ
YLVPILTQTLTKQDENDDDDDWNPCKAAGVCLMLLATCCEDDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPS
QLKPLVIQAMPTLIELMKDPSVVVRDTAAWTVGRICELLPEAAINDVYLAPLLQCLIEGLSAEPRVASNVCWAFSSLAEA
AYEAADVADDQEEPATYCLSSSFELIVQKLLETTDRPDGHQNNLRSSAYESLMEIVKNSAKDCYPAVQKTTLVIMERLQQ
VLQMESHIQSTSDRIQFNDLQSLLCATLQNVLRKVQHQDALQISDVVMASLLRMFQSTAGSGGVQEDALMAVSTLVEVLG
GEFLKYMEAFKPFLGIGLKNYAEYQVCLAAVGLVGDLCRALQSNIIPFCDEVMQLLLENLGNENVHRSVKPQILSVFGDI
ALAIGGEFKKYLEVVLNTLQQASQAQVDKSDYDMVDYLNELRESCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEFILSF
IDHIAGDEDHTDGVVACAAGLIGDLCTAFGKDVLKLVEARPMIHELLTEGRRSKTNKAKTLATWATKELRKLKNQA
;
1  
2 UNP IMA1_HUMAN P52292 ? 2 AARLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNV 11 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9B4Y A 1 ? 876 ? Q14974 1  ? 876 ? 1  876 
2 2 9B4Y B 1 ? 43  ? P52292 11 ? 53  ? 11 53  
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9B4Y HIS A 97  ? UNP Q14974 GLN 97  conflict 97  1 
1 9B4Y ARG A 863 ? UNP Q14974 THR 863 conflict 863 2 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLU A 2   ? THR A 10  ? GLU A 2   THR A 10  1 ? 9  
HELX_P HELX_P2  AA2 ASP A 14  ? ASN A 32  ? ASP A 14  ASN A 32  1 ? 19 
HELX_P HELX_P3  AA3 ASN A 32  ? ASN A 46  ? ASN A 32  ASN A 46  1 ? 15 
HELX_P HELX_P4  AA4 SER A 50  ? THR A 66  ? SER A 50  THR A 66  1 ? 17 
HELX_P HELX_P5  AA5 ASP A 69  ? ALA A 82  ? ASP A 69  ALA A 82  1 ? 14 
HELX_P HELX_P6  AA6 ASP A 84  ? LEU A 99  ? ASP A 84  LEU A 99  1 ? 16 
HELX_P HELX_P7  AA7 SER A 107 ? ASN A 124 ? SER A 107 ASN A 124 1 ? 18 
HELX_P HELX_P8  AA8 GLU A 128 ? ASN A 139 ? GLU A 128 ASN A 139 1 ? 12 
HELX_P HELX_P9  AA9 THR A 143 ? ILE A 161 ? THR A 143 ILE A 161 1 ? 19 
HELX_P HELX_P10 AB1 ASP A 162 ? ASP A 168 ? ASP A 162 ASP A 168 5 ? 7  
HELX_P HELX_P11 AB2 LYS A 169 ? GLY A 180 ? LYS A 169 GLY A 180 1 ? 12 
HELX_P HELX_P12 AB3 SER A 187 ? SER A 201 ? SER A 187 SER A 201 1 ? 15 
HELX_P HELX_P13 AB4 THR A 205 ? ASP A 210 ? THR A 205 ASP A 210 1 ? 6  
HELX_P HELX_P14 AB5 LYS A 211 ? THR A 226 ? LYS A 211 THR A 226 1 ? 16 
HELX_P HELX_P15 AB6 ASP A 230 ? TYR A 248 ? ASP A 230 TYR A 248 1 ? 19 
HELX_P HELX_P16 AB7 TYR A 249 ? MET A 256 ? TYR A 249 MET A 256 5 ? 8  
HELX_P HELX_P17 AB8 ALA A 259 ? LYS A 269 ? ALA A 259 LYS A 269 1 ? 11 
HELX_P HELX_P18 AB9 ILE A 272 ? GLY A 304 ? ILE A 272 GLY A 304 1 ? 33 
HELX_P HELX_P19 AC1 ALA A 318 ? LEU A 330 ? ALA A 318 LEU A 330 1 ? 13 
HELX_P HELX_P20 AC2 ASN A 343 ? GLU A 360 ? ASN A 343 GLU A 360 1 ? 18 
HELX_P HELX_P21 AC3 ILE A 363 ? ILE A 375 ? ILE A 363 ILE A 375 1 ? 13 
HELX_P HELX_P22 AC4 ASP A 379 ? ILE A 393 ? ASP A 379 ILE A 393 1 ? 15 
HELX_P HELX_P23 AC5 GLU A 398 ? MET A 417 ? GLU A 398 MET A 417 1 ? 20 
HELX_P HELX_P24 AC6 SER A 421 ? LEU A 439 ? SER A 421 LEU A 439 1 ? 19 
HELX_P HELX_P25 AC7 LEU A 439 ? ILE A 444 ? LEU A 439 ILE A 444 1 ? 6  
HELX_P HELX_P26 AC8 ASN A 445 ? LEU A 460 ? ASN A 445 LEU A 460 1 ? 16 
HELX_P HELX_P27 AC9 GLU A 463 ? ASP A 489 ? GLU A 463 ASP A 489 1 ? 27 
HELX_P HELX_P28 AD1 LEU A 499 ? THR A 514 ? LEU A 499 THR A 514 1 ? 16 
HELX_P HELX_P29 AD2 HIS A 520 ? ASN A 522 ? HIS A 520 ASN A 522 5 ? 3  
HELX_P HELX_P30 AD3 ASN A 523 ? ASN A 538 ? ASN A 523 ASN A 538 1 ? 16 
HELX_P HELX_P31 AD4 ALA A 540 ? ASP A 542 ? ALA A 540 ASP A 542 5 ? 3  
HELX_P HELX_P32 AD5 CYS A 543 ? GLN A 563 ? CYS A 543 GLN A 563 1 ? 21 
HELX_P HELX_P33 AD6 SER A 570 ? ARG A 593 ? SER A 570 ARG A 593 1 ? 24 
HELX_P HELX_P34 AD7 GLN A 596 ? THR A 618 ? GLN A 596 THR A 618 1 ? 23 
HELX_P HELX_P35 AD8 SER A 621 ? GLY A 640 ? SER A 621 GLY A 640 1 ? 20 
HELX_P HELX_P36 AD9 GLU A 642 ? TYR A 646 ? GLU A 642 TYR A 646 5 ? 5  
HELX_P HELX_P37 AE1 PHE A 650 ? LYS A 659 ? PHE A 650 LYS A 659 1 ? 10 
HELX_P HELX_P38 AE2 GLU A 663 ? GLN A 682 ? GLU A 663 GLN A 682 1 ? 20 
HELX_P HELX_P39 AE3 ILE A 685 ? ASN A 702 ? ILE A 685 ASN A 702 1 ? 18 
HELX_P HELX_P40 AE4 SER A 708 ? GLY A 725 ? SER A 708 GLY A 725 1 ? 18 
HELX_P HELX_P41 AE5 PHE A 728 ? ALA A 745 ? PHE A 728 ALA A 745 1 ? 18 
HELX_P HELX_P42 AE6 ASP A 751 ? GLY A 778 ? ASP A 751 GLY A 778 1 ? 28 
HELX_P HELX_P43 AE7 HIS A 784 ? LEU A 789 ? HIS A 784 LEU A 789 5 ? 6  
HELX_P HELX_P44 AE8 ARG A 793 ? ASP A 807 ? ARG A 793 ASP A 807 1 ? 15 
HELX_P HELX_P45 AE9 THR A 811 ? PHE A 829 ? THR A 811 PHE A 829 1 ? 19 
HELX_P HELX_P46 AF1 GLY A 830 ? ALA A 839 ? GLY A 830 ALA A 839 1 ? 10 
HELX_P HELX_P47 AF2 PRO A 841 ? SER A 853 ? PRO A 841 SER A 853 1 ? 13 
HELX_P HELX_P48 AF3 THR A 855 ? ASN A 874 ? THR A 855 ASN A 874 1 ? 20 
HELX_P HELX_P49 AF4 ARG B 3   ? PHE B 7   ? ARG B 13  PHE B 17  5 ? 5  
HELX_P HELX_P50 AF5 ASP B 13  ? ASN B 42  ? ASP B 23  ASN B 52  1 ? 30 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_pdbx_entry_details.entry_id                   9B4Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 LYS A 332 ? ? -95.03  31.37   
2  1 GLU A 360 ? ? 59.53   -98.84  
3  1 ALA A 462 ? ? -81.55  -158.34 
4  1 ASP A 490 ? ? 59.07   -167.20 
5  1 ASP A 518 ? ? -93.81  30.72   
6  1 ASN A 523 ? ? 39.23   51.63   
7  1 SER A 621 ? ? 55.96   72.11   
8  1 GLN A 682 ? ? 60.62   -119.29 
9  1 GLN A 780 ? ? -141.80 -17.25  
10 1 HIS A 810 ? ? 64.98   163.26  
11 1 LYS B 18  ? ? 59.97   -102.20 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9B4Y 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9B4Y 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.74 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               620000 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Importin Alpha1/Beta/TDP-43 trimeric complex' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2' 
# 
_em_imaging.entry_id                        9B4Y 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             2400 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9B4Y 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9B4Y 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-03-21 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9B4Y 
_em_admin.last_update        2025-05-28 
_em_admin.map_release_date   2025-03-26 
_em_admin.title              'Cryo-EM structure of importin alpha-1/beta bound to TDP-43' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     NONE 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          562 
_em_entity_assembly_recombinant.organism             'Escherichia coli' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     6400 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ?         ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 cryoSPARC ? 
MASKING                         ? 3  ? ? ? ?         ? 
'CTF CORRECTION'                ? 4  1 ? ? ?         ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ?         ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ?         ? 
'MODEL FITTING'                 ? 7  ? ? ? ?         ? 
'MODEL REFINEMENT'              ? 8  ? ? ? PHENIX    ? 
OTHER                           ? 9  ? ? ? ?         ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ?         ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ?         ? 
CLASSIFICATION                  ? 12 1 ? ? ?         ? 
RECONSTRUCTION                  ? 13 1 ? ? ?         ? 
'VOLUME SELECTION'              ? 14 1 1 1 ?         ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ?         ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ?         ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ?         ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ?         ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ?         ? 
# 
_em_specimen.concentration           2.0 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9B4Y 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . MET A 1 1   ? 49.938  70.500  62.916  1.00 384.18 ? 1   MET A N   1 
ATOM 2    C CA  . MET A 1 1   ? 50.899  69.460  62.571  1.00 384.18 ? 1   MET A CA  1 
ATOM 3    C C   . MET A 1 1   ? 51.514  68.875  63.840  1.00 384.18 ? 1   MET A C   1 
ATOM 4    O O   . MET A 1 1   ? 51.574  69.545  64.872  1.00 384.18 ? 1   MET A O   1 
ATOM 5    C CB  . MET A 1 1   ? 51.983  70.018  61.646  1.00 384.18 ? 1   MET A CB  1 
ATOM 6    C CG  . MET A 1 1   ? 52.626  68.985  60.733  1.00 384.18 ? 1   MET A CG  1 
ATOM 7    S SD  . MET A 1 1   ? 53.988  68.094  61.504  1.00 384.18 ? 1   MET A SD  1 
ATOM 8    C CE  . MET A 1 1   ? 55.191  69.409  61.674  1.00 384.18 ? 1   MET A CE  1 
ATOM 9    N N   . GLU A 1 2   ? 51.961  67.623  63.761  1.00 378.57 ? 2   GLU A N   1 
ATOM 10   C CA  . GLU A 1 2   ? 52.483  66.936  64.935  1.00 378.57 ? 2   GLU A CA  1 
ATOM 11   C C   . GLU A 1 2   ? 53.766  67.600  65.420  1.00 378.57 ? 2   GLU A C   1 
ATOM 12   O O   . GLU A 1 2   ? 54.651  67.927  64.623  1.00 378.57 ? 2   GLU A O   1 
ATOM 13   C CB  . GLU A 1 2   ? 52.742  65.462  64.619  1.00 378.57 ? 2   GLU A CB  1 
ATOM 14   C CG  . GLU A 1 2   ? 51.570  64.737  63.975  1.00 378.57 ? 2   GLU A CG  1 
ATOM 15   C CD  . GLU A 1 2   ? 51.595  64.817  62.461  1.00 378.57 ? 2   GLU A CD  1 
ATOM 16   O OE1 . GLU A 1 2   ? 52.657  65.162  61.901  1.00 378.57 ? 2   GLU A OE1 1 
ATOM 17   O OE2 . GLU A 1 2   ? 50.554  64.537  61.831  1.00 378.57 ? 2   GLU A OE2 1 
ATOM 18   N N   . LEU A 1 3   ? 53.867  67.797  66.736  1.00 368.73 ? 3   LEU A N   1 
ATOM 19   C CA  . LEU A 1 3   ? 55.073  68.373  67.317  1.00 368.73 ? 3   LEU A CA  1 
ATOM 20   C C   . LEU A 1 3   ? 56.235  67.389  67.342  1.00 368.73 ? 3   LEU A C   1 
ATOM 21   O O   . LEU A 1 3   ? 57.387  67.817  67.474  1.00 368.73 ? 3   LEU A O   1 
ATOM 22   C CB  . LEU A 1 3   ? 54.798  68.878  68.737  1.00 368.73 ? 3   LEU A CB  1 
ATOM 23   C CG  . LEU A 1 3   ? 54.624  67.853  69.860  1.00 368.73 ? 3   LEU A CG  1 
ATOM 24   C CD1 . LEU A 1 3   ? 54.881  68.511  71.205  1.00 368.73 ? 3   LEU A CD1 1 
ATOM 25   C CD2 . LEU A 1 3   ? 53.236  67.228  69.834  1.00 368.73 ? 3   LEU A CD2 1 
ATOM 26   N N   . ILE A 1 4   ? 55.960  66.088  67.227  1.00 366.89 ? 4   ILE A N   1 
ATOM 27   C CA  . ILE A 1 4   ? 57.037  65.108  67.141  1.00 366.89 ? 4   ILE A CA  1 
ATOM 28   C C   . ILE A 1 4   ? 57.858  65.326  65.878  1.00 366.89 ? 4   ILE A C   1 
ATOM 29   O O   . ILE A 1 4   ? 59.094  65.259  65.912  1.00 366.89 ? 4   ILE A O   1 
ATOM 30   C CB  . ILE A 1 4   ? 56.467  63.679  67.207  1.00 366.89 ? 4   ILE A CB  1 
ATOM 31   C CG1 . ILE A 1 4   ? 55.675  63.481  68.500  1.00 366.89 ? 4   ILE A CG1 1 
ATOM 32   C CG2 . ILE A 1 4   ? 57.584  62.651  67.102  1.00 366.89 ? 4   ILE A CG2 1 
ATOM 33   C CD1 . ILE A 1 4   ? 55.084  62.096  68.647  1.00 366.89 ? 4   ILE A CD1 1 
ATOM 34   N N   . THR A 1 5   ? 57.195  65.586  64.749  1.00 381.34 ? 5   THR A N   1 
ATOM 35   C CA  . THR A 1 5   ? 57.914  65.894  63.517  1.00 381.34 ? 5   THR A CA  1 
ATOM 36   C C   . THR A 1 5   ? 58.704  67.191  63.651  1.00 381.34 ? 5   THR A C   1 
ATOM 37   O O   . THR A 1 5   ? 59.775  67.337  63.051  1.00 381.34 ? 5   THR A O   1 
ATOM 38   C CB  . THR A 1 5   ? 56.933  65.979  62.346  1.00 381.34 ? 5   THR A CB  1 
ATOM 39   O OG1 . THR A 1 5   ? 56.115  64.802  62.322  1.00 381.34 ? 5   THR A OG1 1 
ATOM 40   C CG2 . THR A 1 5   ? 57.681  66.091  61.025  1.00 381.34 ? 5   THR A CG2 1 
ATOM 41   N N   . ILE A 1 6   ? 58.190  68.142  64.435  1.00 384.13 ? 6   ILE A N   1 
ATOM 42   C CA  . ILE A 1 6   ? 58.914  69.388  64.670  1.00 384.13 ? 6   ILE A CA  1 
ATOM 43   C C   . ILE A 1 6   ? 60.236  69.113  65.376  1.00 384.13 ? 6   ILE A C   1 
ATOM 44   O O   . ILE A 1 6   ? 61.271  69.700  65.036  1.00 384.13 ? 6   ILE A O   1 
ATOM 45   C CB  . ILE A 1 6   ? 58.039  70.373  65.468  1.00 384.13 ? 6   ILE A CB  1 
ATOM 46   C CG1 . ILE A 1 6   ? 56.732  70.654  64.725  1.00 384.13 ? 6   ILE A CG1 1 
ATOM 47   C CG2 . ILE A 1 6   ? 58.793  71.669  65.730  1.00 384.13 ? 6   ILE A CG2 1 
ATOM 48   C CD1 . ILE A 1 6   ? 55.812  71.611  65.450  1.00 384.13 ? 6   ILE A CD1 1 
ATOM 49   N N   . LEU A 1 7   ? 60.224  68.220  66.369  1.00 372.31 ? 7   LEU A N   1 
ATOM 50   C CA  . LEU A 1 7   ? 61.453  67.876  67.075  1.00 372.31 ? 7   LEU A CA  1 
ATOM 51   C C   . LEU A 1 7   ? 62.466  67.208  66.154  1.00 372.31 ? 7   LEU A C   1 
ATOM 52   O O   . LEU A 1 7   ? 63.675  67.301  66.392  1.00 372.31 ? 7   LEU A O   1 
ATOM 53   C CB  . LEU A 1 7   ? 61.138  66.965  68.262  1.00 372.31 ? 7   LEU A CB  1 
ATOM 54   C CG  . LEU A 1 7   ? 60.139  67.501  69.290  1.00 372.31 ? 7   LEU A CG  1 
ATOM 55   C CD1 . LEU A 1 7   ? 59.831  66.444  70.338  1.00 372.31 ? 7   LEU A CD1 1 
ATOM 56   C CD2 . LEU A 1 7   ? 60.666  68.770  69.942  1.00 372.31 ? 7   LEU A CD2 1 
ATOM 57   N N   . GLU A 1 8   ? 61.999  66.522  65.108  1.00 376.02 ? 8   GLU A N   1 
ATOM 58   C CA  . GLU A 1 8   ? 62.923  65.910  64.160  1.00 376.02 ? 8   GLU A CA  1 
ATOM 59   C C   . GLU A 1 8   ? 63.517  66.949  63.215  1.00 376.02 ? 8   GLU A C   1 
ATOM 60   O O   . GLU A 1 8   ? 64.692  66.856  62.840  1.00 376.02 ? 8   GLU A O   1 
ATOM 61   C CB  . GLU A 1 8   ? 62.212  64.809  63.373  1.00 376.02 ? 8   GLU A CB  1 
ATOM 62   C CG  . GLU A 1 8   ? 63.105  64.063  62.391  1.00 376.02 ? 8   GLU A CG  1 
ATOM 63   C CD  . GLU A 1 8   ? 64.174  63.236  63.080  1.00 376.02 ? 8   GLU A CD  1 
ATOM 64   O OE1 . GLU A 1 8   ? 63.974  62.854  64.252  1.00 376.02 ? 8   GLU A OE1 1 
ATOM 65   O OE2 . GLU A 1 8   ? 65.218  62.967  62.448  1.00 376.02 ? 8   GLU A OE2 1 
ATOM 66   N N   . LYS A 1 9   ? 62.722  67.948  62.823  1.00 386.67 ? 9   LYS A N   1 
ATOM 67   C CA  . LYS A 1 9   ? 63.179  68.930  61.844  1.00 386.67 ? 9   LYS A CA  1 
ATOM 68   C C   . LYS A 1 9   ? 64.226  69.882  62.407  1.00 386.67 ? 9   LYS A C   1 
ATOM 69   O O   . LYS A 1 9   ? 65.097  70.342  61.660  1.00 386.67 ? 9   LYS A O   1 
ATOM 70   C CB  . LYS A 1 9   ? 61.990  69.723  61.299  1.00 386.67 ? 9   LYS A CB  1 
ATOM 71   C CG  . LYS A 1 9   ? 61.240  69.016  60.183  1.00 386.67 ? 9   LYS A CG  1 
ATOM 72   C CD  . LYS A 1 9   ? 62.165  68.726  59.011  1.00 386.67 ? 9   LYS A CD  1 
ATOM 73   C CE  . LYS A 1 9   ? 61.432  68.028  57.878  1.00 386.67 ? 9   LYS A CE  1 
ATOM 74   N NZ  . LYS A 1 9   ? 62.339  67.738  56.734  1.00 386.67 ? 9   LYS A NZ  1 
ATOM 75   N N   . THR A 1 10  ? 64.167  70.195  63.701  1.00 392.02 ? 10  THR A N   1 
ATOM 76   C CA  . THR A 1 10  ? 65.136  71.105  64.299  1.00 392.02 ? 10  THR A CA  1 
ATOM 77   C C   . THR A 1 10  ? 66.543  70.522  64.353  1.00 392.02 ? 10  THR A C   1 
ATOM 78   O O   . THR A 1 10  ? 67.493  71.262  64.633  1.00 392.02 ? 10  THR A O   1 
ATOM 79   C CB  . THR A 1 10  ? 64.692  71.511  65.708  1.00 392.02 ? 10  THR A CB  1 
ATOM 80   O OG1 . THR A 1 10  ? 65.613  72.470  66.244  1.00 392.02 ? 10  THR A OG1 1 
ATOM 81   C CG2 . THR A 1 10  ? 64.648  70.304  66.620  1.00 392.02 ? 10  THR A CG2 1 
ATOM 82   N N   . VAL A 1 11  ? 66.699  69.224  64.105  1.00 385.70 ? 11  VAL A N   1 
ATOM 83   C CA  . VAL A 1 11  ? 68.016  68.616  63.982  1.00 385.70 ? 11  VAL A CA  1 
ATOM 84   C C   . VAL A 1 11  ? 68.353  68.254  62.538  1.00 385.70 ? 11  VAL A C   1 
ATOM 85   O O   . VAL A 1 11  ? 69.533  68.017  62.237  1.00 385.70 ? 11  VAL A O   1 
ATOM 86   C CB  . VAL A 1 11  ? 68.143  67.373  64.888  1.00 385.70 ? 11  VAL A CB  1 
ATOM 87   C CG1 . VAL A 1 11  ? 69.605  67.083  65.208  1.00 385.70 ? 11  VAL A CG1 1 
ATOM 88   C CG2 . VAL A 1 11  ? 67.339  67.562  66.164  1.00 385.70 ? 11  VAL A CG2 1 
ATOM 89   N N   . SER A 1 12  ? 67.370  68.216  61.642  1.00 391.58 ? 12  SER A N   1 
ATOM 90   C CA  . SER A 1 12  ? 67.638  67.873  60.254  1.00 391.58 ? 12  SER A CA  1 
ATOM 91   C C   . SER A 1 12  ? 68.434  68.988  59.578  1.00 391.58 ? 12  SER A C   1 
ATOM 92   O O   . SER A 1 12  ? 68.293  70.161  59.939  1.00 391.58 ? 12  SER A O   1 
ATOM 93   C CB  . SER A 1 12  ? 66.328  67.636  59.502  1.00 391.58 ? 12  SER A CB  1 
ATOM 94   O OG  . SER A 1 12  ? 65.525  68.803  59.497  1.00 391.58 ? 12  SER A OG  1 
ATOM 95   N N   . PRO A 1 13  ? 69.279  68.658  58.598  1.00 395.75 ? 13  PRO A N   1 
ATOM 96   C CA  . PRO A 1 13  ? 70.090  69.684  57.905  1.00 395.75 ? 13  PRO A CA  1 
ATOM 97   C C   . PRO A 1 13  ? 69.310  70.463  56.847  1.00 395.75 ? 13  PRO A C   1 
ATOM 98   O O   . PRO A 1 13  ? 69.340  70.185  55.648  1.00 395.75 ? 13  PRO A O   1 
ATOM 99   C CB  . PRO A 1 13  ? 71.218  68.855  57.288  1.00 395.75 ? 13  PRO A CB  1 
ATOM 100  C CG  . PRO A 1 13  ? 70.596  67.523  57.035  1.00 395.75 ? 13  PRO A CG  1 
ATOM 101  C CD  . PRO A 1 13  ? 69.626  67.293  58.164  1.00 395.75 ? 13  PRO A CD  1 
ATOM 102  N N   . ASP A 1 14  ? 68.585  71.481  57.305  1.00 396.77 ? 14  ASP A N   1 
ATOM 103  C CA  . ASP A 1 14  ? 67.833  72.356  56.412  1.00 396.77 ? 14  ASP A CA  1 
ATOM 104  C C   . ASP A 1 14  ? 67.646  73.696  57.105  1.00 396.77 ? 14  ASP A C   1 
ATOM 105  O O   . ASP A 1 14  ? 67.054  73.755  58.187  1.00 396.77 ? 14  ASP A O   1 
ATOM 106  C CB  . ASP A 1 14  ? 66.481  71.742  56.041  1.00 396.77 ? 14  ASP A CB  1 
ATOM 107  C CG  . ASP A 1 14  ? 65.790  72.486  54.913  1.00 396.77 ? 14  ASP A CG  1 
ATOM 108  O OD1 . ASP A 1 14  ? 66.387  73.439  54.370  1.00 396.77 ? 14  ASP A OD1 1 
ATOM 109  O OD2 . ASP A 1 14  ? 64.648  72.116  54.568  1.00 396.77 ? 14  ASP A OD2 1 
ATOM 110  N N   . ARG A 1 15  ? 68.149  74.764  56.481  1.00 398.22 ? 15  ARG A N   1 
ATOM 111  C CA  . ARG A 1 15  ? 68.084  76.086  57.096  1.00 398.22 ? 15  ARG A CA  1 
ATOM 112  C C   . ARG A 1 15  ? 66.649  76.573  57.251  1.00 398.22 ? 15  ARG A C   1 
ATOM 113  O O   . ARG A 1 15  ? 66.312  77.185  58.271  1.00 398.22 ? 15  ARG A O   1 
ATOM 114  C CB  . ARG A 1 15  ? 68.892  77.088  56.271  1.00 398.22 ? 15  ARG A CB  1 
ATOM 115  C CG  . ARG A 1 15  ? 70.257  76.588  55.808  1.00 398.22 ? 15  ARG A CG  1 
ATOM 116  C CD  . ARG A 1 15  ? 71.224  76.367  56.965  1.00 398.22 ? 15  ARG A CD  1 
ATOM 117  N NE  . ARG A 1 15  ? 71.082  75.046  57.567  1.00 398.22 ? 15  ARG A NE  1 
ATOM 118  C CZ  . ARG A 1 15  ? 71.668  73.948  57.110  1.00 398.22 ? 15  ARG A CZ  1 
ATOM 119  N NH1 . ARG A 1 15  ? 72.442  73.973  56.037  1.00 398.22 ? 15  ARG A NH1 1 
ATOM 120  N NH2 . ARG A 1 15  ? 71.470  72.795  57.743  1.00 398.22 ? 15  ARG A NH2 1 
ATOM 121  N N   . LEU A 1 16  ? 65.797  76.318  56.255  1.00 405.40 ? 16  LEU A N   1 
ATOM 122  C CA  . LEU A 1 16  ? 64.417  76.791  56.317  1.00 405.40 ? 16  LEU A CA  1 
ATOM 123  C C   . LEU A 1 16  ? 63.654  76.128  57.457  1.00 405.40 ? 16  LEU A C   1 
ATOM 124  O O   . LEU A 1 16  ? 62.833  76.771  58.122  1.00 405.40 ? 16  LEU A O   1 
ATOM 125  C CB  . LEU A 1 16  ? 63.718  76.538  54.982  1.00 405.40 ? 16  LEU A CB  1 
ATOM 126  C CG  . LEU A 1 16  ? 62.337  77.170  54.796  1.00 405.40 ? 16  LEU A CG  1 
ATOM 127  C CD1 . LEU A 1 16  ? 62.438  78.687  54.813  1.00 405.40 ? 16  LEU A CD1 1 
ATOM 128  C CD2 . LEU A 1 16  ? 61.694  76.686  53.507  1.00 405.40 ? 16  LEU A CD2 1 
ATOM 129  N N   . GLU A 1 17  ? 63.904  74.838  57.692  1.00 404.11 ? 17  GLU A N   1 
ATOM 130  C CA  . GLU A 1 17  ? 63.218  74.133  58.770  1.00 404.11 ? 17  GLU A CA  1 
ATOM 131  C C   . GLU A 1 17  ? 63.608  74.686  60.136  1.00 404.11 ? 17  GLU A C   1 
ATOM 132  O O   . GLU A 1 17  ? 62.764  74.785  61.034  1.00 404.11 ? 17  GLU A O   1 
ATOM 133  C CB  . GLU A 1 17  ? 63.519  72.636  58.693  1.00 404.11 ? 17  GLU A CB  1 
ATOM 134  C CG  . GLU A 1 17  ? 63.056  71.968  57.406  1.00 404.11 ? 17  GLU A CG  1 
ATOM 135  C CD  . GLU A 1 17  ? 61.546  71.855  57.307  1.00 404.11 ? 17  GLU A CD  1 
ATOM 136  O OE1 . GLU A 1 17  ? 60.867  71.962  58.350  1.00 404.11 ? 17  GLU A OE1 1 
ATOM 137  O OE2 . GLU A 1 17  ? 61.037  71.657  56.184  1.00 404.11 ? 17  GLU A OE2 1 
ATOM 138  N N   . LEU A 1 18  ? 64.884  75.040  60.315  1.00 402.28 ? 18  LEU A N   1 
ATOM 139  C CA  . LEU A 1 18  ? 65.348  75.515  61.616  1.00 402.28 ? 18  LEU A CA  1 
ATOM 140  C C   . LEU A 1 18  ? 64.658  76.815  62.012  1.00 402.28 ? 18  LEU A C   1 
ATOM 141  O O   . LEU A 1 18  ? 64.204  76.968  63.152  1.00 402.28 ? 18  LEU A O   1 
ATOM 142  C CB  . LEU A 1 18  ? 66.866  75.699  61.596  1.00 402.28 ? 18  LEU A CB  1 
ATOM 143  C CG  . LEU A 1 18  ? 67.706  74.463  61.267  1.00 402.28 ? 18  LEU A CG  1 
ATOM 144  C CD1 . LEU A 1 18  ? 69.189  74.759  61.435  1.00 402.28 ? 18  LEU A CD1 1 
ATOM 145  C CD2 . LEU A 1 18  ? 67.287  73.283  62.126  1.00 402.28 ? 18  LEU A CD2 1 
ATOM 146  N N   . GLU A 1 19  ? 64.569  77.768  61.081  1.00 404.96 ? 19  GLU A N   1 
ATOM 147  C CA  . GLU A 1 19  ? 63.938  79.044  61.403  1.00 404.96 ? 19  GLU A CA  1 
ATOM 148  C C   . GLU A 1 19  ? 62.431  78.899  61.577  1.00 404.96 ? 19  GLU A C   1 
ATOM 149  O O   . GLU A 1 19  ? 61.843  79.569  62.433  1.00 404.96 ? 19  GLU A O   1 
ATOM 150  C CB  . GLU A 1 19  ? 64.270  80.086  60.330  1.00 404.96 ? 19  GLU A CB  1 
ATOM 151  C CG  . GLU A 1 19  ? 63.731  79.787  58.938  1.00 404.96 ? 19  GLU A CG  1 
ATOM 152  C CD  . GLU A 1 19  ? 62.346  80.364  58.711  1.00 404.96 ? 19  GLU A CD  1 
ATOM 153  O OE1 . GLU A 1 19  ? 61.903  81.190  59.537  1.00 404.96 ? 19  GLU A OE1 1 
ATOM 154  O OE2 . GLU A 1 19  ? 61.700  79.991  57.710  1.00 404.96 ? 19  GLU A OE2 1 
ATOM 155  N N   . ALA A 1 20  ? 61.791  78.040  60.779  1.00 401.34 ? 20  ALA A N   1 
ATOM 156  C CA  . ALA A 1 20  ? 60.357  77.818  60.932  1.00 401.34 ? 20  ALA A CA  1 
ATOM 157  C C   . ALA A 1 20  ? 60.041  77.163  62.270  1.00 401.34 ? 20  ALA A C   1 
ATOM 158  O O   . ALA A 1 20  ? 59.085  77.556  62.950  1.00 401.34 ? 20  ALA A O   1 
ATOM 159  C CB  . ALA A 1 20  ? 59.830  76.967  59.777  1.00 401.34 ? 20  ALA A CB  1 
ATOM 160  N N   . ALA A 1 21  ? 60.828  76.158  62.662  1.00 394.94 ? 21  ALA A N   1 
ATOM 161  C CA  . ALA A 1 21  ? 60.622  75.517  63.956  1.00 394.94 ? 21  ALA A CA  1 
ATOM 162  C C   . ALA A 1 21  ? 60.896  76.483  65.102  1.00 394.94 ? 21  ALA A C   1 
ATOM 163  O O   . ALA A 1 21  ? 60.136  76.529  66.077  1.00 394.94 ? 21  ALA A O   1 
ATOM 164  C CB  . ALA A 1 21  ? 61.506  74.277  64.075  1.00 394.94 ? 21  ALA A CB  1 
ATOM 165  N N   . GLN A 1 22  ? 61.977  77.261  65.003  1.00 389.27 ? 22  GLN A N   1 
ATOM 166  C CA  . GLN A 1 22  ? 62.299  78.217  66.057  1.00 389.27 ? 22  GLN A CA  1 
ATOM 167  C C   . GLN A 1 22  ? 61.219  79.284  66.186  1.00 389.27 ? 22  GLN A C   1 
ATOM 168  O O   . GLN A 1 22  ? 60.832  79.651  67.301  1.00 389.27 ? 22  GLN A O   1 
ATOM 169  C CB  . GLN A 1 22  ? 63.659  78.860  65.786  1.00 389.27 ? 22  GLN A CB  1 
ATOM 170  C CG  . GLN A 1 22  ? 64.116  79.833  66.863  1.00 389.27 ? 22  GLN A CG  1 
ATOM 171  C CD  . GLN A 1 22  ? 64.467  79.143  68.168  1.00 389.27 ? 22  GLN A CD  1 
ATOM 172  O OE1 . GLN A 1 22  ? 64.367  79.735  69.242  1.00 389.27 ? 22  GLN A OE1 1 
ATOM 173  N NE2 . GLN A 1 22  ? 64.888  77.887  68.079  1.00 389.27 ? 22  GLN A NE2 1 
ATOM 174  N N   . LYS A 1 23  ? 60.724  79.796  65.056  1.00 390.12 ? 23  LYS A N   1 
ATOM 175  C CA  . LYS A 1 23  ? 59.664  80.799  65.100  1.00 390.12 ? 23  LYS A CA  1 
ATOM 176  C C   . LYS A 1 23  ? 58.382  80.224  65.689  1.00 390.12 ? 23  LYS A C   1 
ATOM 177  O O   . LYS A 1 23  ? 57.727  80.873  66.513  1.00 390.12 ? 23  LYS A O   1 
ATOM 178  C CB  . LYS A 1 23  ? 59.414  81.358  63.698  1.00 390.12 ? 23  LYS A CB  1 
ATOM 179  C CG  . LYS A 1 23  ? 58.339  82.436  63.625  1.00 390.12 ? 23  LYS A CG  1 
ATOM 180  C CD  . LYS A 1 23  ? 57.013  81.875  63.130  1.00 390.12 ? 23  LYS A CD  1 
ATOM 181  C CE  . LYS A 1 23  ? 55.931  82.943  63.112  1.00 390.12 ? 23  LYS A CE  1 
ATOM 182  N NZ  . LYS A 1 23  ? 54.617  82.392  62.679  1.00 390.12 ? 23  LYS A NZ  1 
ATOM 183  N N   . PHE A 1 24  ? 58.006  79.011  65.276  1.00 390.91 ? 24  PHE A N   1 
ATOM 184  C CA  . PHE A 1 24  ? 56.779  78.404  65.784  1.00 390.91 ? 24  PHE A CA  1 
ATOM 185  C C   . PHE A 1 24  ? 56.880  78.102  67.274  1.00 390.91 ? 24  PHE A C   1 
ATOM 186  O O   . PHE A 1 24  ? 55.939  78.370  68.031  1.00 390.91 ? 24  PHE A O   1 
ATOM 187  C CB  . PHE A 1 24  ? 56.459  77.132  64.998  1.00 390.91 ? 24  PHE A CB  1 
ATOM 188  C CG  . PHE A 1 24  ? 55.991  77.390  63.594  1.00 390.91 ? 24  PHE A CG  1 
ATOM 189  C CD1 . PHE A 1 24  ? 55.435  78.610  63.249  1.00 390.91 ? 24  PHE A CD1 1 
ATOM 190  C CD2 . PHE A 1 24  ? 56.105  76.412  62.620  1.00 390.91 ? 24  PHE A CD2 1 
ATOM 191  C CE1 . PHE A 1 24  ? 55.003  78.852  61.960  1.00 390.91 ? 24  PHE A CE1 1 
ATOM 192  C CE2 . PHE A 1 24  ? 55.675  76.647  61.328  1.00 390.91 ? 24  PHE A CE2 1 
ATOM 193  C CZ  . PHE A 1 24  ? 55.123  77.869  60.998  1.00 390.91 ? 24  PHE A CZ  1 
ATOM 194  N N   . LEU A 1 25  ? 58.010  77.542  67.715  1.00 377.80 ? 25  LEU A N   1 
ATOM 195  C CA  . LEU A 1 25  ? 58.176  77.237  69.133  1.00 377.80 ? 25  LEU A CA  1 
ATOM 196  C C   . LEU A 1 25  ? 58.205  78.507  69.975  1.00 377.80 ? 25  LEU A C   1 
ATOM 197  O O   . LEU A 1 25  ? 57.598  78.557  71.052  1.00 377.80 ? 25  LEU A O   1 
ATOM 198  C CB  . LEU A 1 25  ? 59.447  76.415  69.348  1.00 377.80 ? 25  LEU A CB  1 
ATOM 199  C CG  . LEU A 1 25  ? 59.412  74.988  68.794  1.00 377.80 ? 25  LEU A CG  1 
ATOM 200  C CD1 . LEU A 1 25  ? 60.781  74.335  68.888  1.00 377.80 ? 25  LEU A CD1 1 
ATOM 201  C CD2 . LEU A 1 25  ? 58.369  74.154  69.522  1.00 377.80 ? 25  LEU A CD2 1 
ATOM 202  N N   . GLU A 1 26  ? 58.908  79.541  69.506  1.00 375.89 ? 26  GLU A N   1 
ATOM 203  C CA  . GLU A 1 26  ? 58.938  80.805  70.236  1.00 375.89 ? 26  GLU A CA  1 
ATOM 204  C C   . GLU A 1 26  ? 57.560  81.455  70.276  1.00 375.89 ? 26  GLU A C   1 
ATOM 205  O O   . GLU A 1 26  ? 57.136  81.957  71.323  1.00 375.89 ? 26  GLU A O   1 
ATOM 206  C CB  . GLU A 1 26  ? 59.961  81.751  69.607  1.00 375.89 ? 26  GLU A CB  1 
ATOM 207  C CG  . GLU A 1 26  ? 59.997  83.137  70.235  1.00 375.89 ? 26  GLU A CG  1 
ATOM 208  C CD  . GLU A 1 26  ? 60.465  83.118  71.679  1.00 375.89 ? 26  GLU A CD  1 
ATOM 209  O OE1 . GLU A 1 26  ? 61.202  82.183  72.058  1.00 375.89 ? 26  GLU A OE1 1 
ATOM 210  O OE2 . GLU A 1 26  ? 60.093  84.039  72.435  1.00 375.89 ? 26  GLU A OE2 1 
ATOM 211  N N   . ARG A 1 27  ? 56.850  81.459  69.144  1.00 377.21 ? 27  ARG A N   1 
ATOM 212  C CA  . ARG A 1 27  ? 55.509  82.034  69.114  1.00 377.21 ? 27  ARG A CA  1 
ATOM 213  C C   . ARG A 1 27  ? 54.553  81.253  70.007  1.00 377.21 ? 27  ARG A C   1 
ATOM 214  O O   . ARG A 1 27  ? 53.769  81.848  70.755  1.00 377.21 ? 27  ARG A O   1 
ATOM 215  C CB  . ARG A 1 27  ? 54.995  82.082  67.674  1.00 377.21 ? 27  ARG A CB  1 
ATOM 216  C CG  . ARG A 1 27  ? 53.603  82.680  67.503  1.00 377.21 ? 27  ARG A CG  1 
ATOM 217  C CD  . ARG A 1 27  ? 52.536  81.598  67.413  1.00 377.21 ? 27  ARG A CD  1 
ATOM 218  N NE  . ARG A 1 27  ? 52.875  80.584  66.421  1.00 377.21 ? 27  ARG A NE  1 
ATOM 219  C CZ  . ARG A 1 27  ? 52.175  79.477  66.211  1.00 377.21 ? 27  ARG A CZ  1 
ATOM 220  N NH1 . ARG A 1 27  ? 51.085  79.206  66.910  1.00 377.21 ? 27  ARG A NH1 1 
ATOM 221  N NH2 . ARG A 1 27  ? 52.581  78.620  65.279  1.00 377.21 ? 27  ARG A NH2 1 
ATOM 222  N N   . ALA A 1 28  ? 54.603  79.919  69.943  1.00 376.88 ? 28  ALA A N   1 
ATOM 223  C CA  . ALA A 1 28  ? 53.708  79.102  70.754  1.00 376.88 ? 28  ALA A CA  1 
ATOM 224  C C   . ALA A 1 28  ? 53.986  79.263  72.243  1.00 376.88 ? 28  ALA A C   1 
ATOM 225  O O   . ALA A 1 28  ? 53.046  79.295  73.046  1.00 376.88 ? 28  ALA A O   1 
ATOM 226  C CB  . ALA A 1 28  ? 53.822  77.632  70.351  1.00 376.88 ? 28  ALA A CB  1 
ATOM 227  N N   . ALA A 1 29  ? 55.261  79.355  72.630  1.00 377.65 ? 29  ALA A N   1 
ATOM 228  C CA  . ALA A 1 29  ? 55.595  79.536  74.039  1.00 377.65 ? 29  ALA A CA  1 
ATOM 229  C C   . ALA A 1 29  ? 55.033  80.846  74.577  1.00 377.65 ? 29  ALA A C   1 
ATOM 230  O O   . ALA A 1 29  ? 54.499  80.887  75.691  1.00 377.65 ? 29  ALA A O   1 
ATOM 231  C CB  . ALA A 1 29  ? 57.110  79.480  74.231  1.00 377.65 ? 29  ALA A CB  1 
ATOM 232  N N   . VAL A 1 30  ? 55.149  81.927  73.804  1.00 381.85 ? 30  VAL A N   1 
ATOM 233  C CA  . VAL A 1 30  ? 54.575  83.200  74.226  1.00 381.85 ? 30  VAL A CA  1 
ATOM 234  C C   . VAL A 1 30  ? 53.053  83.148  74.164  1.00 381.85 ? 30  VAL A C   1 
ATOM 235  O O   . VAL A 1 30  ? 52.364  83.656  75.057  1.00 381.85 ? 30  VAL A O   1 
ATOM 236  C CB  . VAL A 1 30  ? 55.141  84.349  73.371  1.00 381.85 ? 30  VAL A CB  1 
ATOM 237  C CG1 . VAL A 1 30  ? 54.533  85.678  73.792  1.00 381.85 ? 30  VAL A CG1 1 
ATOM 238  C CG2 . VAL A 1 30  ? 56.657  84.393  73.482  1.00 381.85 ? 30  VAL A CG2 1 
ATOM 239  N N   . GLU A 1 31  ? 52.504  82.536  73.111  1.00 378.53 ? 31  GLU A N   1 
ATOM 240  C CA  . GLU A 1 31  ? 51.054  82.495  72.944  1.00 378.53 ? 31  GLU A CA  1 
ATOM 241  C C   . GLU A 1 31  ? 50.388  81.691  74.056  1.00 378.53 ? 31  GLU A C   1 
ATOM 242  O O   . GLU A 1 31  ? 49.457  82.174  74.711  1.00 378.53 ? 31  GLU A O   1 
ATOM 243  C CB  . GLU A 1 31  ? 50.702  81.913  71.575  1.00 378.53 ? 31  GLU A CB  1 
ATOM 244  C CG  . GLU A 1 31  ? 49.228  82.002  71.214  1.00 378.53 ? 31  GLU A CG  1 
ATOM 245  C CD  . GLU A 1 31  ? 48.799  83.409  70.843  1.00 378.53 ? 31  GLU A CD  1 
ATOM 246  O OE1 . GLU A 1 31  ? 49.682  84.252  70.578  1.00 378.53 ? 31  GLU A OE1 1 
ATOM 247  O OE2 . GLU A 1 31  ? 47.579  83.671  70.814  1.00 378.53 ? 31  GLU A OE2 1 
ATOM 248  N N   . ASN A 1 32  ? 50.851  80.460  74.284  1.00 362.91 ? 32  ASN A N   1 
ATOM 249  C CA  . ASN A 1 32  ? 50.292  79.591  75.325  1.00 362.91 ? 32  ASN A CA  1 
ATOM 250  C C   . ASN A 1 32  ? 51.457  78.869  75.999  1.00 362.91 ? 32  ASN A C   1 
ATOM 251  O O   . ASN A 1 32  ? 51.848  77.775  75.583  1.00 362.91 ? 32  ASN A O   1 
ATOM 252  C CB  . ASN A 1 32  ? 49.279  78.614  74.740  1.00 362.91 ? 32  ASN A CB  1 
ATOM 253  C CG  . ASN A 1 32  ? 48.415  77.960  75.803  1.00 362.91 ? 32  ASN A CG  1 
ATOM 254  O OD1 . ASN A 1 32  ? 48.819  77.830  76.958  1.00 362.91 ? 32  ASN A OD1 1 
ATOM 255  N ND2 . ASN A 1 32  ? 47.215  77.544  75.413  1.00 362.91 ? 32  ASN A ND2 1 
ATOM 256  N N   . LEU A 1 33  ? 52.008  79.493  77.045  1.00 343.72 ? 33  LEU A N   1 
ATOM 257  C CA  . LEU A 1 33  ? 53.102  78.859  77.780  1.00 343.72 ? 33  LEU A CA  1 
ATOM 258  C C   . LEU A 1 33  ? 52.663  77.602  78.524  1.00 343.72 ? 33  LEU A C   1 
ATOM 259  O O   . LEU A 1 33  ? 53.344  76.570  78.397  1.00 343.72 ? 33  LEU A O   1 
ATOM 260  C CB  . LEU A 1 33  ? 53.755  79.877  78.720  1.00 343.72 ? 33  LEU A CB  1 
ATOM 261  C CG  . LEU A 1 33  ? 55.074  79.450  79.368  1.00 343.72 ? 33  LEU A CG  1 
ATOM 262  C CD1 . LEU A 1 33  ? 56.122  79.161  78.304  1.00 343.72 ? 33  LEU A CD1 1 
ATOM 263  C CD2 . LEU A 1 33  ? 55.570  80.514  80.334  1.00 343.72 ? 33  LEU A CD2 1 
ATOM 264  N N   . PRO A 1 34  ? 51.573  77.601  79.306  1.00 347.67 ? 34  PRO A N   1 
ATOM 265  C CA  . PRO A 1 34  ? 51.274  76.395  80.099  1.00 347.67 ? 34  PRO A CA  1 
ATOM 266  C C   . PRO A 1 34  ? 50.913  75.182  79.261  1.00 347.67 ? 34  PRO A C   1 
ATOM 267  O O   . PRO A 1 34  ? 51.492  74.107  79.463  1.00 347.67 ? 34  PRO A O   1 
ATOM 268  C CB  . PRO A 1 34  ? 50.098  76.838  80.984  1.00 347.67 ? 34  PRO A CB  1 
ATOM 269  C CG  . PRO A 1 34  ? 50.145  78.325  80.981  1.00 347.67 ? 34  PRO A CG  1 
ATOM 270  C CD  . PRO A 1 34  ? 50.636  78.694  79.623  1.00 347.67 ? 34  PRO A CD  1 
ATOM 271  N N   . THR A 1 35  ? 49.968  75.319  78.328  1.00 357.01 ? 35  THR A N   1 
ATOM 272  C CA  . THR A 1 35  ? 49.488  74.157  77.583  1.00 357.01 ? 35  THR A CA  1 
ATOM 273  C C   . THR A 1 35  ? 50.586  73.553  76.714  1.00 357.01 ? 35  THR A C   1 
ATOM 274  O O   . THR A 1 35  ? 50.731  72.326  76.654  1.00 357.01 ? 35  THR A O   1 
ATOM 275  C CB  . THR A 1 35  ? 48.282  74.544  76.727  1.00 357.01 ? 35  THR A CB  1 
ATOM 276  O OG1 . THR A 1 35  ? 47.263  75.107  77.563  1.00 357.01 ? 35  THR A OG1 1 
ATOM 277  C CG2 . THR A 1 35  ? 47.721  73.324  76.010  1.00 357.01 ? 35  THR A CG2 1 
ATOM 278  N N   . PHE A 1 36  ? 51.367  74.396  76.034  1.00 352.95 ? 36  PHE A N   1 
ATOM 279  C CA  . PHE A 1 36  ? 52.393  73.885  75.129  1.00 352.95 ? 36  PHE A CA  1 
ATOM 280  C C   . PHE A 1 36  ? 53.480  73.132  75.887  1.00 352.95 ? 36  PHE A C   1 
ATOM 281  O O   . PHE A 1 36  ? 53.966  72.096  75.418  1.00 352.95 ? 36  PHE A O   1 
ATOM 282  C CB  . PHE A 1 36  ? 52.991  75.033  74.317  1.00 352.95 ? 36  PHE A CB  1 
ATOM 283  C CG  . PHE A 1 36  ? 53.528  74.613  72.979  1.00 352.95 ? 36  PHE A CG  1 
ATOM 284  C CD1 . PHE A 1 36  ? 52.672  74.170  71.984  1.00 352.95 ? 36  PHE A CD1 1 
ATOM 285  C CD2 . PHE A 1 36  ? 54.885  74.673  72.710  1.00 352.95 ? 36  PHE A CD2 1 
ATOM 286  C CE1 . PHE A 1 36  ? 53.159  73.785  70.750  1.00 352.95 ? 36  PHE A CE1 1 
ATOM 287  C CE2 . PHE A 1 36  ? 55.378  74.291  71.476  1.00 352.95 ? 36  PHE A CE2 1 
ATOM 288  C CZ  . PHE A 1 36  ? 54.514  73.846  70.496  1.00 352.95 ? 36  PHE A CZ  1 
ATOM 289  N N   . LEU A 1 37  ? 53.879  73.638  77.057  1.00 344.28 ? 37  LEU A N   1 
ATOM 290  C CA  . LEU A 1 37  ? 54.875  72.940  77.864  1.00 344.28 ? 37  LEU A CA  1 
ATOM 291  C C   . LEU A 1 37  ? 54.356  71.589  78.340  1.00 344.28 ? 37  LEU A C   1 
ATOM 292  O O   . LEU A 1 37  ? 55.113  70.613  78.396  1.00 344.28 ? 37  LEU A O   1 
ATOM 293  C CB  . LEU A 1 37  ? 55.295  73.807  79.050  1.00 344.28 ? 37  LEU A CB  1 
ATOM 294  C CG  . LEU A 1 37  ? 56.179  75.008  78.708  1.00 344.28 ? 37  LEU A CG  1 
ATOM 295  C CD1 . LEU A 1 37  ? 56.474  75.832  79.949  1.00 344.28 ? 37  LEU A CD1 1 
ATOM 296  C CD2 . LEU A 1 37  ? 57.469  74.549  78.045  1.00 344.28 ? 37  LEU A CD2 1 
ATOM 297  N N   . VAL A 1 38  ? 53.072  71.516  78.697  1.00 346.21 ? 38  VAL A N   1 
ATOM 298  C CA  . VAL A 1 38  ? 52.476  70.237  79.073  1.00 346.21 ? 38  VAL A CA  1 
ATOM 299  C C   . VAL A 1 38  ? 52.517  69.268  77.898  1.00 346.21 ? 38  VAL A C   1 
ATOM 300  O O   . VAL A 1 38  ? 52.834  68.083  78.060  1.00 346.21 ? 38  VAL A O   1 
ATOM 301  C CB  . VAL A 1 38  ? 51.039  70.446  79.588  1.00 346.21 ? 38  VAL A CB  1 
ATOM 302  C CG1 . VAL A 1 38  ? 50.340  69.109  79.783  1.00 346.21 ? 38  VAL A CG1 1 
ATOM 303  C CG2 . VAL A 1 38  ? 51.054  71.234  80.889  1.00 346.21 ? 38  VAL A CG2 1 
ATOM 304  N N   . GLU A 1 39  ? 52.198  69.756  76.697  1.00 347.17 ? 39  GLU A N   1 
ATOM 305  C CA  . GLU A 1 39  ? 52.282  68.915  75.507  1.00 347.17 ? 39  GLU A CA  1 
ATOM 306  C C   . GLU A 1 39  ? 53.715  68.465  75.248  1.00 347.17 ? 39  GLU A C   1 
ATOM 307  O O   . GLU A 1 39  ? 53.952  67.305  74.891  1.00 347.17 ? 39  GLU A O   1 
ATOM 308  C CB  . GLU A 1 39  ? 51.725  69.664  74.297  1.00 347.17 ? 39  GLU A CB  1 
ATOM 309  C CG  . GLU A 1 39  ? 51.721  68.857  73.008  1.00 347.17 ? 39  GLU A CG  1 
ATOM 310  C CD  . GLU A 1 39  ? 50.718  67.719  73.030  1.00 347.17 ? 39  GLU A CD  1 
ATOM 311  O OE1 . GLU A 1 39  ? 49.757  67.784  73.826  1.00 347.17 ? 39  GLU A OE1 1 
ATOM 312  O OE2 . GLU A 1 39  ? 50.890  66.760  72.249  1.00 347.17 ? 39  GLU A OE2 1 
ATOM 313  N N   . LEU A 1 40  ? 54.683  69.371  75.416  1.00 342.39 ? 40  LEU A N   1 
ATOM 314  C CA  . LEU A 1 40  ? 56.083  68.999  75.235  1.00 342.39 ? 40  LEU A CA  1 
ATOM 315  C C   . LEU A 1 40  ? 56.514  67.955  76.257  1.00 342.39 ? 40  LEU A C   1 
ATOM 316  O O   . LEU A 1 40  ? 57.208  66.990  75.914  1.00 342.39 ? 40  LEU A O   1 
ATOM 317  C CB  . LEU A 1 40  ? 56.975  70.238  75.328  1.00 342.39 ? 40  LEU A CB  1 
ATOM 318  C CG  . LEU A 1 40  ? 57.430  70.856  74.004  1.00 342.39 ? 40  LEU A CG  1 
ATOM 319  C CD1 . LEU A 1 40  ? 58.265  69.861  73.212  1.00 342.39 ? 40  LEU A CD1 1 
ATOM 320  C CD2 . LEU A 1 40  ? 56.239  71.326  73.187  1.00 342.39 ? 40  LEU A CD2 1 
ATOM 321  N N   . SER A 1 41  ? 56.110  68.129  77.518  1.00 339.48 ? 41  SER A N   1 
ATOM 322  C CA  . SER A 1 41  ? 56.476  67.168  78.553  1.00 339.48 ? 41  SER A CA  1 
ATOM 323  C C   . SER A 1 41  ? 55.854  65.802  78.300  1.00 339.48 ? 41  SER A C   1 
ATOM 324  O O   . SER A 1 41  ? 56.478  64.775  78.592  1.00 339.48 ? 41  SER A O   1 
ATOM 325  C CB  . SER A 1 41  ? 56.063  67.694  79.927  1.00 339.48 ? 41  SER A CB  1 
ATOM 326  O OG  . SER A 1 41  ? 54.665  67.914  79.989  1.00 339.48 ? 41  SER A OG  1 
ATOM 327  N N   . ARG A 1 42  ? 54.629  65.769  77.771  1.00 338.27 ? 42  ARG A N   1 
ATOM 328  C CA  . ARG A 1 42  ? 53.977  64.495  77.480  1.00 338.27 ? 42  ARG A CA  1 
ATOM 329  C C   . ARG A 1 42  ? 54.733  63.714  76.412  1.00 338.27 ? 42  ARG A C   1 
ATOM 330  O O   . ARG A 1 42  ? 54.876  62.490  76.515  1.00 338.27 ? 42  ARG A O   1 
ATOM 331  C CB  . ARG A 1 42  ? 52.531  64.736  77.047  1.00 338.27 ? 42  ARG A CB  1 
ATOM 332  C CG  . ARG A 1 42  ? 51.722  63.465  76.836  1.00 338.27 ? 42  ARG A CG  1 
ATOM 333  C CD  . ARG A 1 42  ? 50.326  63.760  76.300  1.00 338.27 ? 42  ARG A CD  1 
ATOM 334  N NE  . ARG A 1 42  ? 49.543  64.595  77.205  1.00 338.27 ? 42  ARG A NE  1 
ATOM 335  C CZ  . ARG A 1 42  ? 49.326  65.892  77.030  1.00 338.27 ? 42  ARG A CZ  1 
ATOM 336  N NH1 . ARG A 1 42  ? 49.815  66.541  75.986  1.00 338.27 ? 42  ARG A NH1 1 
ATOM 337  N NH2 . ARG A 1 42  ? 48.598  66.554  77.925  1.00 338.27 ? 42  ARG A NH2 1 
ATOM 338  N N   . VAL A 1 43  ? 55.220  64.403  75.378  1.00 344.96 ? 43  VAL A N   1 
ATOM 339  C CA  . VAL A 1 43  ? 55.895  63.722  74.276  1.00 344.96 ? 43  VAL A CA  1 
ATOM 340  C C   . VAL A 1 43  ? 57.227  63.139  74.736  1.00 344.96 ? 43  VAL A C   1 
ATOM 341  O O   . VAL A 1 43  ? 57.542  61.976  74.458  1.00 344.96 ? 43  VAL A O   1 
ATOM 342  C CB  . VAL A 1 43  ? 56.077  64.682  73.087  1.00 344.96 ? 43  VAL A CB  1 
ATOM 343  C CG1 . VAL A 1 43  ? 56.935  64.039  72.009  1.00 344.96 ? 43  VAL A CG1 1 
ATOM 344  C CG2 . VAL A 1 43  ? 54.723  65.081  72.523  1.00 344.96 ? 43  VAL A CG2 1 
ATOM 345  N N   . LEU A 1 44  ? 58.030  63.934  75.447  1.00 331.06 ? 44  LEU A N   1 
ATOM 346  C CA  . LEU A 1 44  ? 59.340  63.469  75.887  1.00 331.06 ? 44  LEU A CA  1 
ATOM 347  C C   . LEU A 1 44  ? 59.254  62.363  76.930  1.00 331.06 ? 44  LEU A C   1 
ATOM 348  O O   . LEU A 1 44  ? 60.158  61.523  76.996  1.00 331.06 ? 44  LEU A O   1 
ATOM 349  C CB  . LEU A 1 44  ? 60.169  64.640  76.428  1.00 331.06 ? 44  LEU A CB  1 
ATOM 350  C CG  . LEU A 1 44  ? 59.595  65.549  77.519  1.00 331.06 ? 44  LEU A CG  1 
ATOM 351  C CD1 . LEU A 1 44  ? 59.860  65.006  78.916  1.00 331.06 ? 44  LEU A CD1 1 
ATOM 352  C CD2 . LEU A 1 44  ? 60.154  66.955  77.376  1.00 331.06 ? 44  LEU A CD2 1 
ATOM 353  N N   . ALA A 1 45  ? 58.196  62.346  77.744  1.00 326.91 ? 45  ALA A N   1 
ATOM 354  C CA  . ALA A 1 45  ? 58.035  61.293  78.740  1.00 326.91 ? 45  ALA A CA  1 
ATOM 355  C C   . ALA A 1 45  ? 57.794  59.927  78.111  1.00 326.91 ? 45  ALA A C   1 
ATOM 356  O O   . ALA A 1 45  ? 58.017  58.908  78.774  1.00 326.91 ? 45  ALA A O   1 
ATOM 357  C CB  . ALA A 1 45  ? 56.887  61.637  79.690  1.00 326.91 ? 45  ALA A CB  1 
ATOM 358  N N   . ASN A 1 46  ? 57.342  59.880  76.862  1.00 329.13 ? 46  ASN A N   1 
ATOM 359  C CA  . ASN A 1 46  ? 57.075  58.608  76.200  1.00 329.13 ? 46  ASN A CA  1 
ATOM 360  C C   . ASN A 1 46  ? 58.385  57.942  75.799  1.00 329.13 ? 46  ASN A C   1 
ATOM 361  O O   . ASN A 1 46  ? 59.159  58.532  75.036  1.00 329.13 ? 46  ASN A O   1 
ATOM 362  C CB  . ASN A 1 46  ? 56.199  58.822  74.972  1.00 329.13 ? 46  ASN A CB  1 
ATOM 363  C CG  . ASN A 1 46  ? 55.952  57.540  74.200  1.00 329.13 ? 46  ASN A CG  1 
ATOM 364  O OD1 . ASN A 1 46  ? 55.936  56.449  74.771  1.00 329.13 ? 46  ASN A OD1 1 
ATOM 365  N ND2 . ASN A 1 46  ? 55.760  57.665  72.892  1.00 329.13 ? 46  ASN A ND2 1 
ATOM 366  N N   . PRO A 1 47  ? 58.674  56.728  76.279  1.00 321.79 ? 47  PRO A N   1 
ATOM 367  C CA  . PRO A 1 47  ? 59.909  56.048  75.856  1.00 321.79 ? 47  PRO A CA  1 
ATOM 368  C C   . PRO A 1 47  ? 59.892  55.599  74.406  1.00 321.79 ? 47  PRO A C   1 
ATOM 369  O O   . PRO A 1 47  ? 60.967  55.354  73.842  1.00 321.79 ? 47  PRO A O   1 
ATOM 370  C CB  . PRO A 1 47  ? 59.995  54.844  76.807  1.00 321.79 ? 47  PRO A CB  1 
ATOM 371  C CG  . PRO A 1 47  ? 59.060  55.164  77.938  1.00 321.79 ? 47  PRO A CG  1 
ATOM 372  C CD  . PRO A 1 47  ? 57.967  55.982  77.331  1.00 321.79 ? 47  PRO A CD  1 
ATOM 373  N N   . GLY A 1 48  ? 58.719  55.482  73.784  1.00 326.19 ? 48  GLY A N   1 
ATOM 374  C CA  . GLY A 1 48  ? 58.635  54.988  72.421  1.00 326.19 ? 48  GLY A CA  1 
ATOM 375  C C   . GLY A 1 48  ? 59.073  55.975  71.360  1.00 326.19 ? 48  GLY A C   1 
ATOM 376  O O   . GLY A 1 48  ? 59.287  55.567  70.213  1.00 326.19 ? 48  GLY A O   1 
ATOM 377  N N   . ASN A 1 49  ? 59.214  57.249  71.709  1.00 325.93 ? 49  ASN A N   1 
ATOM 378  C CA  . ASN A 1 49  ? 59.660  58.245  70.750  1.00 325.93 ? 49  ASN A CA  1 
ATOM 379  C C   . ASN A 1 49  ? 61.148  58.076  70.459  1.00 325.93 ? 49  ASN A C   1 
ATOM 380  O O   . ASN A 1 49  ? 61.913  57.549  71.271  1.00 325.93 ? 49  ASN A O   1 
ATOM 381  C CB  . ASN A 1 49  ? 59.382  59.657  71.269  1.00 325.93 ? 49  ASN A CB  1 
ATOM 382  C CG  . ASN A 1 49  ? 57.902  59.930  71.449  1.00 325.93 ? 49  ASN A CG  1 
ATOM 383  O OD1 . ASN A 1 49  ? 57.066  59.397  70.719  1.00 325.93 ? 49  ASN A OD1 1 
ATOM 384  N ND2 . ASN A 1 49  ? 57.570  60.767  72.425  1.00 325.93 ? 49  ASN A ND2 1 
ATOM 385  N N   . SER A 1 50  ? 61.550  58.526  69.273  1.00 316.91 ? 50  SER A N   1 
ATOM 386  C CA  . SER A 1 50  ? 62.947  58.444  68.874  1.00 316.91 ? 50  SER A CA  1 
ATOM 387  C C   . SER A 1 50  ? 63.820  59.294  69.790  1.00 316.91 ? 50  SER A C   1 
ATOM 388  O O   . SER A 1 50  ? 63.426  60.375  70.235  1.00 316.91 ? 50  SER A O   1 
ATOM 389  C CB  . SER A 1 50  ? 63.117  58.896  67.423  1.00 316.91 ? 50  SER A CB  1 
ATOM 390  O OG  . SER A 1 50  ? 62.708  60.242  67.257  1.00 316.91 ? 50  SER A OG  1 
ATOM 391  N N   . GLN A 1 51  ? 65.023  58.786  70.071  1.00 296.40 ? 51  GLN A N   1 
ATOM 392  C CA  . GLN A 1 51  ? 65.933  59.480  70.976  1.00 296.40 ? 51  GLN A CA  1 
ATOM 393  C C   . GLN A 1 51  ? 66.329  60.851  70.441  1.00 296.40 ? 51  GLN A C   1 
ATOM 394  O O   . GLN A 1 51  ? 66.523  61.786  71.226  1.00 296.40 ? 51  GLN A O   1 
ATOM 395  C CB  . GLN A 1 51  ? 67.176  58.625  71.226  1.00 296.40 ? 51  GLN A CB  1 
ATOM 396  C CG  . GLN A 1 51  ? 68.187  59.248  72.177  1.00 296.40 ? 51  GLN A CG  1 
ATOM 397  C CD  . GLN A 1 51  ? 69.369  58.339  72.447  1.00 296.40 ? 51  GLN A CD  1 
ATOM 398  O OE1 . GLN A 1 51  ? 69.223  57.273  73.046  1.00 296.40 ? 51  GLN A OE1 1 
ATOM 399  N NE2 . GLN A 1 51  ? 70.549  58.755  72.002  1.00 296.40 ? 51  GLN A NE2 1 
ATOM 400  N N   . VAL A 1 52  ? 66.447  60.991  69.119  1.00 316.66 ? 52  VAL A N   1 
ATOM 401  C CA  . VAL A 1 52  ? 66.810  62.279  68.535  1.00 316.66 ? 52  VAL A CA  1 
ATOM 402  C C   . VAL A 1 52  ? 65.757  63.331  68.862  1.00 316.66 ? 52  VAL A C   1 
ATOM 403  O O   . VAL A 1 52  ? 66.087  64.469  69.219  1.00 316.66 ? 52  VAL A O   1 
ATOM 404  C CB  . VAL A 1 52  ? 67.019  62.137  67.017  1.00 316.66 ? 52  VAL A CB  1 
ATOM 405  C CG1 . VAL A 1 52  ? 67.434  63.468  66.410  1.00 316.66 ? 52  VAL A CG1 1 
ATOM 406  C CG2 . VAL A 1 52  ? 68.056  61.063  66.722  1.00 316.66 ? 52  VAL A CG2 1 
ATOM 407  N N   . ALA A 1 53  ? 64.476  62.973  68.742  1.00 325.48 ? 53  ALA A N   1 
ATOM 408  C CA  . ALA A 1 53  ? 63.410  63.906  69.092  1.00 325.48 ? 53  ALA A CA  1 
ATOM 409  C C   . ALA A 1 53  ? 63.448  64.259  70.574  1.00 325.48 ? 53  ALA A C   1 
ATOM 410  O O   . ALA A 1 53  ? 63.242  65.421  70.946  1.00 325.48 ? 53  ALA A O   1 
ATOM 411  C CB  . ALA A 1 53  ? 62.052  63.316  68.715  1.00 325.48 ? 53  ALA A CB  1 
ATOM 412  N N   . ARG A 1 54  ? 63.705  63.271  71.434  1.00 310.99 ? 54  ARG A N   1 
ATOM 413  C CA  . ARG A 1 54  ? 63.771  63.533  72.869  1.00 310.99 ? 54  ARG A CA  1 
ATOM 414  C C   . ARG A 1 54  ? 64.926  64.470  73.209  1.00 310.99 ? 54  ARG A C   1 
ATOM 415  O O   . ARG A 1 54  ? 64.782  65.355  74.060  1.00 310.99 ? 54  ARG A O   1 
ATOM 416  C CB  . ARG A 1 54  ? 63.893  62.217  73.636  1.00 310.99 ? 54  ARG A CB  1 
ATOM 417  C CG  . ARG A 1 54  ? 62.839  61.189  73.253  1.00 310.99 ? 54  ARG A CG  1 
ATOM 418  C CD  . ARG A 1 54  ? 62.923  59.942  74.115  1.00 310.99 ? 54  ARG A CD  1 
ATOM 419  N NE  . ARG A 1 54  ? 62.348  60.152  75.438  1.00 310.99 ? 54  ARG A NE  1 
ATOM 420  C CZ  . ARG A 1 54  ? 62.248  59.212  76.368  1.00 310.99 ? 54  ARG A CZ  1 
ATOM 421  N NH1 . ARG A 1 54  ? 62.685  57.982  76.157  1.00 310.99 ? 54  ARG A NH1 1 
ATOM 422  N NH2 . ARG A 1 54  ? 61.696  59.515  77.539  1.00 310.99 ? 54  ARG A NH2 1 
ATOM 423  N N   . VAL A 1 55  ? 66.080  64.285  72.562  1.00 308.94 ? 55  VAL A N   1 
ATOM 424  C CA  . VAL A 1 55  ? 67.198  65.205  72.760  1.00 308.94 ? 55  VAL A CA  1 
ATOM 425  C C   . VAL A 1 55  ? 66.826  66.603  72.282  1.00 308.94 ? 55  VAL A C   1 
ATOM 426  O O   . VAL A 1 55  ? 67.116  67.603  72.950  1.00 308.94 ? 55  VAL A O   1 
ATOM 427  C CB  . VAL A 1 55  ? 68.458  64.681  72.046  1.00 308.94 ? 55  VAL A CB  1 
ATOM 428  C CG1 . VAL A 1 55  ? 69.577  65.709  72.116  1.00 308.94 ? 55  VAL A CG1 1 
ATOM 429  C CG2 . VAL A 1 55  ? 68.906  63.363  72.657  1.00 308.94 ? 55  VAL A CG2 1 
ATOM 430  N N   . ALA A 1 56  ? 66.175  66.693  71.119  1.00 315.86 ? 56  ALA A N   1 
ATOM 431  C CA  . ALA A 1 56  ? 65.751  67.990  70.603  1.00 315.86 ? 56  ALA A CA  1 
ATOM 432  C C   . ALA A 1 56  ? 64.737  68.648  71.529  1.00 315.86 ? 56  ALA A C   1 
ATOM 433  O O   . ALA A 1 56  ? 64.791  69.862  71.758  1.00 315.86 ? 56  ALA A O   1 
ATOM 434  C CB  . ALA A 1 56  ? 65.172  67.829  69.199  1.00 315.86 ? 56  ALA A CB  1 
ATOM 435  N N   . ALA A 1 57  ? 63.799  67.864  72.064  1.00 315.76 ? 57  ALA A N   1 
ATOM 436  C CA  . ALA A 1 57  ? 62.841  68.406  73.021  1.00 315.76 ? 57  ALA A CA  1 
ATOM 437  C C   . ALA A 1 57  ? 63.536  68.874  74.293  1.00 315.76 ? 57  ALA A C   1 
ATOM 438  O O   . ALA A 1 57  ? 63.159  69.900  74.871  1.00 315.76 ? 57  ALA A O   1 
ATOM 439  C CB  . ALA A 1 57  ? 61.774  67.361  73.346  1.00 315.76 ? 57  ALA A CB  1 
ATOM 440  N N   . GLY A 1 58  ? 64.547  68.130  74.747  1.00 307.94 ? 58  GLY A N   1 
ATOM 441  C CA  . GLY A 1 58  ? 65.263  68.526  75.949  1.00 307.94 ? 58  GLY A CA  1 
ATOM 442  C C   . GLY A 1 58  ? 65.987  69.850  75.798  1.00 307.94 ? 58  GLY A C   1 
ATOM 443  O O   . GLY A 1 58  ? 65.909  70.712  76.678  1.00 307.94 ? 58  GLY A O   1 
ATOM 444  N N   . LEU A 1 59  ? 66.703  70.032  74.685  1.00 309.68 ? 59  LEU A N   1 
ATOM 445  C CA  . LEU A 1 59  ? 67.426  71.283  74.477  1.00 309.68 ? 59  LEU A CA  1 
ATOM 446  C C   . LEU A 1 59  ? 66.478  72.445  74.209  1.00 309.68 ? 59  LEU A C   1 
ATOM 447  O O   . LEU A 1 59  ? 66.755  73.574  74.630  1.00 309.68 ? 59  LEU A O   1 
ATOM 448  C CB  . LEU A 1 59  ? 68.439  71.129  73.339  1.00 309.68 ? 59  LEU A CB  1 
ATOM 449  C CG  . LEU A 1 59  ? 67.977  70.678  71.950  1.00 309.68 ? 59  LEU A CG  1 
ATOM 450  C CD1 . LEU A 1 59  ? 67.615  71.866  71.068  1.00 309.68 ? 59  LEU A CD1 1 
ATOM 451  C CD2 . LEU A 1 59  ? 69.049  69.825  71.289  1.00 309.68 ? 59  LEU A CD2 1 
ATOM 452  N N   . GLN A 1 60  ? 65.366  72.196  73.511  1.00 314.33 ? 60  GLN A N   1 
ATOM 453  C CA  . GLN A 1 60  ? 64.387  73.256  73.284  1.00 314.33 ? 60  GLN A CA  1 
ATOM 454  C C   . GLN A 1 60  ? 63.809  73.765  74.599  1.00 314.33 ? 60  GLN A C   1 
ATOM 455  O O   . GLN A 1 60  ? 63.692  74.979  74.804  1.00 314.33 ? 60  GLN A O   1 
ATOM 456  C CB  . GLN A 1 60  ? 63.271  72.757  72.367  1.00 314.33 ? 60  GLN A CB  1 
ATOM 457  C CG  . GLN A 1 60  ? 62.037  73.648  72.350  1.00 314.33 ? 60  GLN A CG  1 
ATOM 458  C CD  . GLN A 1 60  ? 62.339  75.067  71.900  1.00 314.33 ? 60  GLN A CD  1 
ATOM 459  O OE1 . GLN A 1 60  ? 63.238  75.298  71.092  1.00 314.33 ? 60  GLN A OE1 1 
ATOM 460  N NE2 . GLN A 1 60  ? 61.585  76.026  72.426  1.00 314.33 ? 60  GLN A NE2 1 
ATOM 461  N N   . ILE A 1 61  ? 63.445  72.852  75.502  1.00 305.51 ? 61  ILE A N   1 
ATOM 462  C CA  . ILE A 1 61  ? 62.987  73.264  76.824  1.00 305.51 ? 61  ILE A CA  1 
ATOM 463  C C   . ILE A 1 61  ? 64.126  73.913  77.600  1.00 305.51 ? 61  ILE A C   1 
ATOM 464  O O   . ILE A 1 61  ? 63.921  74.893  78.326  1.00 305.51 ? 61  ILE A O   1 
ATOM 465  C CB  . ILE A 1 61  ? 62.382  72.065  77.577  1.00 305.51 ? 61  ILE A CB  1 
ATOM 466  C CG1 . ILE A 1 61  ? 61.121  71.578  76.861  1.00 305.51 ? 61  ILE A CG1 1 
ATOM 467  C CG2 . ILE A 1 61  ? 62.061  72.435  79.016  1.00 305.51 ? 61  ILE A CG2 1 
ATOM 468  C CD1 . ILE A 1 61  ? 60.299  70.592  77.660  1.00 305.51 ? 61  ILE A CD1 1 
ATOM 469  N N   . LYS A 1 62  ? 65.345  73.385  77.454  1.00 294.42 ? 62  LYS A N   1 
ATOM 470  C CA  . LYS A 1 62  ? 66.501  74.006  78.092  1.00 294.42 ? 62  LYS A CA  1 
ATOM 471  C C   . LYS A 1 62  ? 66.703  75.433  77.598  1.00 294.42 ? 62  LYS A C   1 
ATOM 472  O O   . LYS A 1 62  ? 66.954  76.344  78.395  1.00 294.42 ? 62  LYS A O   1 
ATOM 473  C CB  . LYS A 1 62  ? 67.755  73.171  77.835  1.00 294.42 ? 62  LYS A CB  1 
ATOM 474  C CG  . LYS A 1 62  ? 69.033  73.780  78.393  1.00 294.42 ? 62  LYS A CG  1 
ATOM 475  C CD  . LYS A 1 62  ? 70.264  73.075  77.847  1.00 294.42 ? 62  LYS A CD  1 
ATOM 476  C CE  . LYS A 1 62  ? 70.328  73.180  76.332  1.00 294.42 ? 62  LYS A CE  1 
ATOM 477  N NZ  . LYS A 1 62  ? 71.507  72.466  75.768  1.00 294.42 ? 62  LYS A NZ  1 
ATOM 478  N N   . ASN A 1 63  ? 66.592  75.648  76.285  1.00 304.63 ? 63  ASN A N   1 
ATOM 479  C CA  . ASN A 1 63  ? 66.737  76.994  75.742  1.00 304.63 ? 63  ASN A CA  1 
ATOM 480  C C   . ASN A 1 63  ? 65.652  77.931  76.261  1.00 304.63 ? 63  ASN A C   1 
ATOM 481  O O   . ASN A 1 63  ? 65.939  79.090  76.582  1.00 304.63 ? 63  ASN A O   1 
ATOM 482  C CB  . ASN A 1 63  ? 66.719  76.952  74.214  1.00 304.63 ? 63  ASN A CB  1 
ATOM 483  C CG  . ASN A 1 63  ? 67.915  76.219  73.638  1.00 304.63 ? 63  ASN A CG  1 
ATOM 484  O OD1 . ASN A 1 63  ? 69.006  76.244  74.209  1.00 304.63 ? 63  ASN A OD1 1 
ATOM 485  N ND2 . ASN A 1 63  ? 67.715  75.559  72.504  1.00 304.63 ? 63  ASN A ND2 1 
ATOM 486  N N   . SER A 1 64  ? 64.407  77.455  76.341  1.00 299.44 ? 64  SER A N   1 
ATOM 487  C CA  . SER A 1 64  ? 63.334  78.290  76.869  1.00 299.44 ? 64  SER A CA  1 
ATOM 488  C C   . SER A 1 64  ? 63.510  78.567  78.357  1.00 299.44 ? 64  SER A C   1 
ATOM 489  O O   . SER A 1 64  ? 63.299  79.701  78.803  1.00 299.44 ? 64  SER A O   1 
ATOM 490  C CB  . SER A 1 64  ? 61.979  77.631  76.609  1.00 299.44 ? 64  SER A CB  1 
ATOM 491  O OG  . SER A 1 64  ? 61.883  76.379  77.266  1.00 299.44 ? 64  SER A OG  1 
ATOM 492  N N   . LEU A 1 65  ? 63.889  77.555  79.138  1.00 286.46 ? 65  LEU A N   1 
ATOM 493  C CA  . LEU A 1 65  ? 64.025  77.700  80.583  1.00 286.46 ? 65  LEU A CA  1 
ATOM 494  C C   . LEU A 1 65  ? 65.246  78.503  81.009  1.00 286.46 ? 65  LEU A C   1 
ATOM 495  O O   . LEU A 1 65  ? 65.127  79.360  81.890  1.00 286.46 ? 65  LEU A O   1 
ATOM 496  C CB  . LEU A 1 65  ? 64.078  76.323  81.256  1.00 286.46 ? 65  LEU A CB  1 
ATOM 497  C CG  . LEU A 1 65  ? 62.773  75.523  81.282  1.00 286.46 ? 65  LEU A CG  1 
ATOM 498  C CD1 . LEU A 1 65  ? 62.948  74.227  82.061  1.00 286.46 ? 65  LEU A CD1 1 
ATOM 499  C CD2 . LEU A 1 65  ? 61.642  76.355  81.864  1.00 286.46 ? 65  LEU A CD2 1 
ATOM 500  N N   . THR A 1 66  ? 66.410  78.257  80.411  1.00 278.65 ? 66  THR A N   1 
ATOM 501  C CA  . THR A 1 66  ? 67.643  78.916  80.816  1.00 278.65 ? 66  THR A CA  1 
ATOM 502  C C   . THR A 1 66  ? 68.379  79.433  79.587  1.00 278.65 ? 66  THR A C   1 
ATOM 503  O O   . THR A 1 66  ? 68.108  79.027  78.455  1.00 278.65 ? 66  THR A O   1 
ATOM 504  C CB  . THR A 1 66  ? 68.558  77.977  81.619  1.00 278.65 ? 66  THR A CB  1 
ATOM 505  O OG1 . THR A 1 66  ? 69.700  78.706  82.086  1.00 278.65 ? 66  THR A OG1 1 
ATOM 506  C CG2 . THR A 1 66  ? 69.026  76.816  80.759  1.00 278.65 ? 66  THR A CG2 1 
ATOM 507  N N   . SER A 1 67  ? 69.318  80.339  79.832  1.00 269.45 ? 67  SER A N   1 
ATOM 508  C CA  . SER A 1 67  ? 70.069  80.998  78.771  1.00 269.45 ? 67  SER A CA  1 
ATOM 509  C C   . SER A 1 67  ? 71.467  81.300  79.305  1.00 269.45 ? 67  SER A C   1 
ATOM 510  O O   . SER A 1 67  ? 71.882  80.754  80.332  1.00 269.45 ? 67  SER A O   1 
ATOM 511  C CB  . SER A 1 67  ? 69.321  82.254  78.289  1.00 269.45 ? 67  SER A CB  1 
ATOM 512  O OG  . SER A 1 67  ? 70.001  82.877  77.213  1.00 269.45 ? 67  SER A OG  1 
ATOM 513  N N   . LYS A 1 68  ? 72.199  82.167  78.606  1.00 258.72 ? 68  LYS A N   1 
ATOM 514  C CA  . LYS A 1 68  ? 73.536  82.554  79.041  1.00 258.72 ? 68  LYS A CA  1 
ATOM 515  C C   . LYS A 1 68  ? 73.531  83.865  79.820  1.00 258.72 ? 68  LYS A C   1 
ATOM 516  O O   . LYS A 1 68  ? 74.230  83.986  80.832  1.00 258.72 ? 68  LYS A O   1 
ATOM 517  C CB  . LYS A 1 68  ? 74.479  82.675  77.839  1.00 258.72 ? 68  LYS A CB  1 
ATOM 518  C CG  . LYS A 1 68  ? 74.954  81.350  77.250  1.00 258.72 ? 68  LYS A CG  1 
ATOM 519  C CD  . LYS A 1 68  ? 73.907  80.724  76.344  1.00 258.72 ? 68  LYS A CD  1 
ATOM 520  C CE  . LYS A 1 68  ? 73.508  81.669  75.222  1.00 258.72 ? 68  LYS A CE  1 
ATOM 521  N NZ  . LYS A 1 68  ? 72.385  81.123  74.414  1.00 258.72 ? 68  LYS A NZ  1 
ATOM 522  N N   . ASP A 1 69  ? 72.759  84.847  79.369  1.00 254.41 ? 69  ASP A N   1 
ATOM 523  C CA  . ASP A 1 69  ? 72.695  86.130  80.061  1.00 254.41 ? 69  ASP A CA  1 
ATOM 524  C C   . ASP A 1 69  ? 71.810  86.005  81.297  1.00 254.41 ? 69  ASP A C   1 
ATOM 525  O O   . ASP A 1 69  ? 70.646  85.609  81.178  1.00 254.41 ? 69  ASP A O   1 
ATOM 526  C CB  . ASP A 1 69  ? 72.153  87.212  79.131  1.00 254.41 ? 69  ASP A CB  1 
ATOM 527  C CG  . ASP A 1 69  ? 72.754  88.576  79.410  1.00 254.41 ? 69  ASP A CG  1 
ATOM 528  O OD1 . ASP A 1 69  ? 73.646  88.670  80.279  1.00 254.41 ? 69  ASP A OD1 1 
ATOM 529  O OD2 . ASP A 1 69  ? 72.336  89.555  78.758  1.00 254.41 ? 69  ASP A OD2 1 
ATOM 530  N N   . PRO A 1 70  ? 72.324  86.321  82.490  1.00 253.48 ? 70  PRO A N   1 
ATOM 531  C CA  . PRO A 1 70  ? 71.514  86.147  83.709  1.00 253.48 ? 70  PRO A CA  1 
ATOM 532  C C   . PRO A 1 70  ? 70.209  86.922  83.706  1.00 253.48 ? 70  PRO A C   1 
ATOM 533  O O   . PRO A 1 70  ? 69.205  86.417  84.225  1.00 253.48 ? 70  PRO A O   1 
ATOM 534  C CB  . PRO A 1 70  ? 72.453  86.637  84.820  1.00 253.48 ? 70  PRO A CB  1 
ATOM 535  C CG  . PRO A 1 70  ? 73.824  86.441  84.266  1.00 253.48 ? 70  PRO A CG  1 
ATOM 536  C CD  . PRO A 1 70  ? 73.707  86.721  82.796  1.00 253.48 ? 70  PRO A CD  1 
ATOM 537  N N   . ASP A 1 71  ? 70.187  88.135  83.145  1.00 256.97 ? 71  ASP A N   1 
ATOM 538  C CA  . ASP A 1 71  ? 68.953  88.915  83.139  1.00 256.97 ? 71  ASP A CA  1 
ATOM 539  C C   . ASP A 1 71  ? 67.861  88.238  82.320  1.00 256.97 ? 71  ASP A C   1 
ATOM 540  O O   . ASP A 1 71  ? 66.694  88.236  82.728  1.00 256.97 ? 71  ASP A O   1 
ATOM 541  C CB  . ASP A 1 71  ? 69.219  90.331  82.623  1.00 256.97 ? 71  ASP A CB  1 
ATOM 542  C CG  . ASP A 1 71  ? 69.832  90.348  81.236  1.00 256.97 ? 71  ASP A CG  1 
ATOM 543  O OD1 . ASP A 1 71  ? 70.106  89.262  80.686  1.00 256.97 ? 71  ASP A OD1 1 
ATOM 544  O OD2 . ASP A 1 71  ? 70.040  91.454  80.695  1.00 256.97 ? 71  ASP A OD2 1 
ATOM 545  N N   . ILE A 1 72  ? 68.215  87.666  81.167  1.00 255.08 ? 72  ILE A N   1 
ATOM 546  C CA  . ILE A 1 72  ? 67.239  86.933  80.367  1.00 255.08 ? 72  ILE A CA  1 
ATOM 547  C C   . ILE A 1 72  ? 66.737  85.712  81.126  1.00 255.08 ? 72  ILE A C   1 
ATOM 548  O O   . ILE A 1 72  ? 65.542  85.393  81.099  1.00 255.08 ? 72  ILE A O   1 
ATOM 549  C CB  . ILE A 1 72  ? 67.848  86.548  79.007  1.00 255.08 ? 72  ILE A CB  1 
ATOM 550  C CG1 . ILE A 1 72  ? 68.335  87.798  78.274  1.00 255.08 ? 72  ILE A CG1 1 
ATOM 551  C CG2 . ILE A 1 72  ? 66.835  85.796  78.158  1.00 255.08 ? 72  ILE A CG2 1 
ATOM 552  C CD1 . ILE A 1 72  ? 68.956  87.514  76.925  1.00 255.08 ? 72  ILE A CD1 1 
ATOM 553  N N   . LYS A 1 73  ? 67.642  85.003  81.805  1.00 261.03 ? 73  LYS A N   1 
ATOM 554  C CA  . LYS A 1 73  ? 67.234  83.862  82.618  1.00 261.03 ? 73  LYS A CA  1 
ATOM 555  C C   . LYS A 1 73  ? 66.323  84.295  83.760  1.00 261.03 ? 73  LYS A C   1 
ATOM 556  O O   . LYS A 1 73  ? 65.336  83.617  84.069  1.00 261.03 ? 73  LYS A O   1 
ATOM 557  C CB  . LYS A 1 73  ? 68.465  83.144  83.170  1.00 261.03 ? 73  LYS A CB  1 
ATOM 558  C CG  . LYS A 1 73  ? 69.505  82.779  82.128  1.00 261.03 ? 73  LYS A CG  1 
ATOM 559  C CD  . LYS A 1 73  ? 70.855  82.508  82.776  1.00 261.03 ? 73  LYS A CD  1 
ATOM 560  C CE  . LYS A 1 73  ? 70.788  81.331  83.734  1.00 261.03 ? 73  LYS A CE  1 
ATOM 561  N NZ  . LYS A 1 73  ? 72.115  81.040  84.342  1.00 261.03 ? 73  LYS A NZ  1 
ATOM 562  N N   . ALA A 1 74  ? 66.644  85.422  84.401  1.00 265.76 ? 74  ALA A N   1 
ATOM 563  C CA  . ALA A 1 74  ? 65.889  85.855  85.573  1.00 265.76 ? 74  ALA A CA  1 
ATOM 564  C C   . ALA A 1 74  ? 64.435  86.148  85.227  1.00 265.76 ? 74  ALA A C   1 
ATOM 565  O O   . ALA A 1 74  ? 63.524  85.731  85.952  1.00 265.76 ? 74  ALA A O   1 
ATOM 566  C CB  . ALA A 1 74  ? 66.550  87.083  86.198  1.00 265.76 ? 74  ALA A CB  1 
ATOM 567  N N   . GLN A 1 75  ? 64.193  86.860  84.123  1.00 269.56 ? 75  GLN A N   1 
ATOM 568  C CA  . GLN A 1 75  ? 62.819  87.166  83.739  1.00 269.56 ? 75  GLN A CA  1 
ATOM 569  C C   . GLN A 1 75  ? 62.080  85.921  83.263  1.00 269.56 ? 75  GLN A C   1 
ATOM 570  O O   . GLN A 1 75  ? 60.858  85.832  83.420  1.00 269.56 ? 75  GLN A O   1 
ATOM 571  C CB  . GLN A 1 75  ? 62.800  88.260  82.670  1.00 269.56 ? 75  GLN A CB  1 
ATOM 572  C CG  . GLN A 1 75  ? 63.723  88.017  81.490  1.00 269.56 ? 75  GLN A CG  1 
ATOM 573  C CD  . GLN A 1 75  ? 63.055  87.246  80.371  1.00 269.56 ? 75  GLN A CD  1 
ATOM 574  O OE1 . GLN A 1 75  ? 61.844  87.029  80.386  1.00 269.56 ? 75  GLN A OE1 1 
ATOM 575  N NE2 . GLN A 1 75  ? 63.845  86.830  79.388  1.00 269.56 ? 75  GLN A NE2 1 
ATOM 576  N N   . TYR A 1 76  ? 62.797  84.957  82.679  1.00 273.47 ? 76  TYR A N   1 
ATOM 577  C CA  . TYR A 1 76  ? 62.175  83.680  82.348  1.00 273.47 ? 76  TYR A CA  1 
ATOM 578  C C   . TYR A 1 76  ? 61.726  82.945  83.605  1.00 273.47 ? 76  TYR A C   1 
ATOM 579  O O   . TYR A 1 76  ? 60.680  82.285  83.605  1.00 273.47 ? 76  TYR A O   1 
ATOM 580  C CB  . TYR A 1 76  ? 63.139  82.819  81.533  1.00 273.47 ? 76  TYR A CB  1 
ATOM 581  C CG  . TYR A 1 76  ? 63.216  83.203  80.073  1.00 273.47 ? 76  TYR A CG  1 
ATOM 582  C CD1 . TYR A 1 76  ? 62.204  83.943  79.475  1.00 273.47 ? 76  TYR A CD1 1 
ATOM 583  C CD2 . TYR A 1 76  ? 64.298  82.820  79.290  1.00 273.47 ? 76  TYR A CD2 1 
ATOM 584  C CE1 . TYR A 1 76  ? 62.269  84.294  78.139  1.00 273.47 ? 76  TYR A CE1 1 
ATOM 585  C CE2 . TYR A 1 76  ? 64.371  83.166  77.954  1.00 273.47 ? 76  TYR A CE2 1 
ATOM 586  C CZ  . TYR A 1 76  ? 63.355  83.903  77.384  1.00 273.47 ? 76  TYR A CZ  1 
ATOM 587  O OH  . TYR A 1 76  ? 63.426  84.249  76.054  1.00 273.47 ? 76  TYR A OH  1 
ATOM 588  N N   . GLN A 1 77  ? 62.509  83.039  84.683  1.00 279.93 ? 77  GLN A N   1 
ATOM 589  C CA  . GLN A 1 77  ? 62.100  82.445  85.952  1.00 279.93 ? 77  GLN A CA  1 
ATOM 590  C C   . GLN A 1 77  ? 60.812  83.075  86.466  1.00 279.93 ? 77  GLN A C   1 
ATOM 591  O O   . GLN A 1 77  ? 59.916  82.371  86.947  1.00 279.93 ? 77  GLN A O   1 
ATOM 592  C CB  . GLN A 1 77  ? 63.216  82.591  86.986  1.00 279.93 ? 77  GLN A CB  1 
ATOM 593  C CG  . GLN A 1 77  ? 64.470  81.794  86.669  1.00 279.93 ? 77  GLN A CG  1 
ATOM 594  C CD  . GLN A 1 77  ? 65.581  82.032  87.673  1.00 279.93 ? 77  GLN A CD  1 
ATOM 595  O OE1 . GLN A 1 77  ? 66.690  81.519  87.523  1.00 279.93 ? 77  GLN A OE1 1 
ATOM 596  N NE2 . GLN A 1 77  ? 65.290  82.817  88.704  1.00 279.93 ? 77  GLN A NE2 1 
ATOM 597  N N   . GLN A 1 78  ? 60.703  84.404  86.380  1.00 288.79 ? 78  GLN A N   1 
ATOM 598  C CA  . GLN A 1 78  ? 59.477  85.074  86.798  1.00 288.79 ? 78  GLN A CA  1 
ATOM 599  C C   . GLN A 1 78  ? 58.300  84.684  85.915  1.00 288.79 ? 78  GLN A C   1 
ATOM 600  O O   . GLN A 1 78  ? 57.173  84.555  86.406  1.00 288.79 ? 78  GLN A O   1 
ATOM 601  C CB  . GLN A 1 78  ? 59.672  86.590  86.785  1.00 288.79 ? 78  GLN A CB  1 
ATOM 602  C CG  . GLN A 1 78  ? 60.989  87.053  87.388  1.00 288.79 ? 78  GLN A CG  1 
ATOM 603  C CD  . GLN A 1 78  ? 61.201  86.544  88.801  1.00 288.79 ? 78  GLN A CD  1 
ATOM 604  O OE1 . GLN A 1 78  ? 60.270  86.498  89.606  1.00 288.79 ? 78  GLN A OE1 1 
ATOM 605  N NE2 . GLN A 1 78  ? 62.433  86.154  89.109  1.00 288.79 ? 78  GLN A NE2 1 
ATOM 606  N N   . ARG A 1 79  ? 58.538  84.508  84.613  1.00 285.47 ? 79  ARG A N   1 
ATOM 607  C CA  . ARG A 1 79  ? 57.475  84.070  83.714  1.00 285.47 ? 79  ARG A CA  1 
ATOM 608  C C   . ARG A 1 79  ? 56.993  82.668  84.071  1.00 285.47 ? 79  ARG A C   1 
ATOM 609  O O   . ARG A 1 79  ? 55.790  82.385  84.008  1.00 285.47 ? 79  ARG A O   1 
ATOM 610  C CB  . ARG A 1 79  ? 57.963  84.121  82.266  1.00 285.47 ? 79  ARG A CB  1 
ATOM 611  C CG  . ARG A 1 79  ? 56.883  83.850  81.231  1.00 285.47 ? 79  ARG A CG  1 
ATOM 612  C CD  . ARG A 1 79  ? 57.442  83.909  79.817  1.00 285.47 ? 79  ARG A CD  1 
ATOM 613  N NE  . ARG A 1 79  ? 58.439  82.873  79.580  1.00 285.47 ? 79  ARG A NE  1 
ATOM 614  C CZ  . ARG A 1 79  ? 59.094  82.709  78.438  1.00 285.47 ? 79  ARG A CZ  1 
ATOM 615  N NH1 . ARG A 1 79  ? 58.884  83.504  77.401  1.00 285.47 ? 79  ARG A NH1 1 
ATOM 616  N NH2 . ARG A 1 79  ? 59.980  81.723  78.334  1.00 285.47 ? 79  ARG A NH2 1 
ATOM 617  N N   . TRP A 1 80  ? 57.916  81.777  84.442  1.00 300.60 ? 80  TRP A N   1 
ATOM 618  C CA  . TRP A 1 80  ? 57.538  80.402  84.753  1.00 300.60 ? 80  TRP A CA  1 
ATOM 619  C C   . TRP A 1 80  ? 56.709  80.318  86.030  1.00 300.60 ? 80  TRP A C   1 
ATOM 620  O O   . TRP A 1 80  ? 55.719  79.580  86.082  1.00 300.60 ? 80  TRP A O   1 
ATOM 621  C CB  . TRP A 1 80  ? 58.785  79.526  84.868  1.00 300.60 ? 80  TRP A CB  1 
ATOM 622  C CG  . TRP A 1 80  ? 58.517  78.203  85.517  1.00 300.60 ? 80  TRP A CG  1 
ATOM 623  C CD1 . TRP A 1 80  ? 58.875  77.822  86.777  1.00 300.60 ? 80  TRP A CD1 1 
ATOM 624  C CD2 . TRP A 1 80  ? 57.820  77.090  84.944  1.00 300.60 ? 80  TRP A CD2 1 
ATOM 625  N NE1 . TRP A 1 80  ? 58.451  76.539  87.022  1.00 300.60 ? 80  TRP A NE1 1 
ATOM 626  C CE2 . TRP A 1 80  ? 57.800  76.067  85.913  1.00 300.60 ? 80  TRP A CE2 1 
ATOM 627  C CE3 . TRP A 1 80  ? 57.214  76.857  83.706  1.00 300.60 ? 80  TRP A CE3 1 
ATOM 628  C CZ2 . TRP A 1 80  ? 57.197  74.833  85.682  1.00 300.60 ? 80  TRP A CZ2 1 
ATOM 629  C CZ3 . TRP A 1 80  ? 56.616  75.630  83.480  1.00 300.60 ? 80  TRP A CZ3 1 
ATOM 630  C CH2 . TRP A 1 80  ? 56.613  74.634  84.462  1.00 300.60 ? 80  TRP A CH2 1 
ATOM 631  N N   . LEU A 1 81  ? 57.099  81.054  87.074  1.00 292.64 ? 81  LEU A N   1 
ATOM 632  C CA  . LEU A 1 81  ? 56.387  80.968  88.345  1.00 292.64 ? 81  LEU A CA  1 
ATOM 633  C C   . LEU A 1 81  ? 54.980  81.549  88.280  1.00 292.64 ? 81  LEU A C   1 
ATOM 634  O O   . LEU A 1 81  ? 54.150  81.203  89.128  1.00 292.64 ? 81  LEU A O   1 
ATOM 635  C CB  . LEU A 1 81  ? 57.192  81.655  89.455  1.00 292.64 ? 81  LEU A CB  1 
ATOM 636  C CG  . LEU A 1 81  ? 57.662  83.105  89.304  1.00 292.64 ? 81  LEU A CG  1 
ATOM 637  C CD1 . LEU A 1 81  ? 56.583  84.101  89.712  1.00 292.64 ? 81  LEU A CD1 1 
ATOM 638  C CD2 . LEU A 1 81  ? 58.931  83.331  90.113  1.00 292.64 ? 81  LEU A CD2 1 
ATOM 639  N N   . ALA A 1 82  ? 54.691  82.414  87.311  1.00 302.07 ? 82  ALA A N   1 
ATOM 640  C CA  . ALA A 1 82  ? 53.349  82.949  87.124  1.00 302.07 ? 82  ALA A CA  1 
ATOM 641  C C   . ALA A 1 82  ? 52.381  81.923  86.550  1.00 302.07 ? 82  ALA A C   1 
ATOM 642  O O   . ALA A 1 82  ? 51.168  82.158  86.565  1.00 302.07 ? 82  ALA A O   1 
ATOM 643  C CB  . ALA A 1 82  ? 53.391  84.181  86.215  1.00 302.07 ? 82  ALA A CB  1 
ATOM 644  N N   . ILE A 1 83  ? 52.888  80.798  86.044  1.00 314.35 ? 83  ILE A N   1 
ATOM 645  C CA  . ILE A 1 83  ? 52.026  79.748  85.519  1.00 314.35 ? 83  ILE A CA  1 
ATOM 646  C C   . ILE A 1 83  ? 51.290  79.075  86.670  1.00 314.35 ? 83  ILE A C   1 
ATOM 647  O O   . ILE A 1 83  ? 51.825  78.938  87.779  1.00 314.35 ? 83  ILE A O   1 
ATOM 648  C CB  . ILE A 1 83  ? 52.859  78.739  84.708  1.00 314.35 ? 83  ILE A CB  1 
ATOM 649  C CG1 . ILE A 1 83  ? 53.637  79.463  83.608  1.00 314.35 ? 83  ILE A CG1 1 
ATOM 650  C CG2 . ILE A 1 83  ? 51.977  77.658  84.101  1.00 314.35 ? 83  ILE A CG2 1 
ATOM 651  C CD1 . ILE A 1 83  ? 52.764  80.280  82.682  1.00 314.35 ? 83  ILE A CD1 1 
ATOM 652  N N   . ASP A 1 84  ? 50.051  78.660  86.413  1.00 320.45 ? 84  ASP A N   1 
ATOM 653  C CA  . ASP A 1 84  ? 49.237  78.036  87.448  1.00 320.45 ? 84  ASP A CA  1 
ATOM 654  C C   . ASP A 1 84  ? 49.869  76.731  87.922  1.00 320.45 ? 84  ASP A C   1 
ATOM 655  O O   . ASP A 1 84  ? 50.586  76.052  87.181  1.00 320.45 ? 84  ASP A O   1 
ATOM 656  C CB  . ASP A 1 84  ? 47.819  77.783  86.931  1.00 320.45 ? 84  ASP A CB  1 
ATOM 657  C CG  . ASP A 1 84  ? 47.801  77.234  85.518  1.00 320.45 ? 84  ASP A CG  1 
ATOM 658  O OD1 . ASP A 1 84  ? 48.876  77.176  84.886  1.00 320.45 ? 84  ASP A OD1 1 
ATOM 659  O OD2 . ASP A 1 84  ? 46.710  76.862  85.038  1.00 320.45 ? 84  ASP A OD2 1 
ATOM 660  N N   . ALA A 1 85  ? 49.595  76.387  89.184  1.00 316.18 ? 85  ALA A N   1 
ATOM 661  C CA  . ALA A 1 85  ? 50.243  75.250  89.827  1.00 316.18 ? 85  ALA A CA  1 
ATOM 662  C C   . ALA A 1 85  ? 49.937  73.924  89.143  1.00 316.18 ? 85  ALA A C   1 
ATOM 663  O O   . ALA A 1 85  ? 50.841  73.092  89.014  1.00 316.18 ? 85  ALA A O   1 
ATOM 664  C CB  . ALA A 1 85  ? 49.831  75.177  91.298  1.00 316.18 ? 85  ALA A CB  1 
ATOM 665  N N   . ASN A 1 86  ? 48.692  73.702  88.715  1.00 318.88 ? 86  ASN A N   1 
ATOM 666  C CA  . ASN A 1 86  ? 48.344  72.429  88.090  1.00 318.88 ? 86  ASN A CA  1 
ATOM 667  C C   . ASN A 1 86  ? 49.151  72.194  86.819  1.00 318.88 ? 86  ASN A C   1 
ATOM 668  O O   . ASN A 1 86  ? 49.651  71.086  86.591  1.00 318.88 ? 86  ASN A O   1 
ATOM 669  C CB  . ASN A 1 86  ? 46.844  72.376  87.798  1.00 318.88 ? 86  ASN A CB  1 
ATOM 670  C CG  . ASN A 1 86  ? 46.348  73.601  87.055  1.00 318.88 ? 86  ASN A CG  1 
ATOM 671  O OD1 . ASN A 1 86  ? 47.137  74.399  86.550  1.00 318.88 ? 86  ASN A OD1 1 
ATOM 672  N ND2 . ASN A 1 86  ? 45.031  73.755  86.984  1.00 318.88 ? 86  ASN A ND2 1 
ATOM 673  N N   . ALA A 1 87  ? 49.289  73.222  85.977  1.00 318.18 ? 87  ALA A N   1 
ATOM 674  C CA  . ALA A 1 87  ? 50.138  73.097  84.797  1.00 318.18 ? 87  ALA A CA  1 
ATOM 675  C C   . ALA A 1 87  ? 51.601  72.914  85.178  1.00 318.18 ? 87  ALA A C   1 
ATOM 676  O O   . ALA A 1 87  ? 52.305  72.112  84.555  1.00 318.18 ? 87  ALA A O   1 
ATOM 677  C CB  . ALA A 1 87  ? 49.972  74.318  83.893  1.00 318.18 ? 87  ALA A CB  1 
ATOM 678  N N   . ARG A 1 88  ? 52.075  73.650  86.187  1.00 311.51 ? 88  ARG A N   1 
ATOM 679  C CA  . ARG A 1 88  ? 53.442  73.459  86.661  1.00 311.51 ? 88  ARG A CA  1 
ATOM 680  C C   . ARG A 1 88  ? 53.631  72.065  87.247  1.00 311.51 ? 88  ARG A C   1 
ATOM 681  O O   . ARG A 1 88  ? 54.665  71.426  87.025  1.00 311.51 ? 88  ARG A O   1 
ATOM 682  C CB  . ARG A 1 88  ? 53.799  74.529  87.693  1.00 311.51 ? 88  ARG A CB  1 
ATOM 683  C CG  . ARG A 1 88  ? 53.922  75.931  87.118  1.00 311.51 ? 88  ARG A CG  1 
ATOM 684  C CD  . ARG A 1 88  ? 54.515  76.896  88.133  1.00 311.51 ? 88  ARG A CD  1 
ATOM 685  N NE  . ARG A 1 88  ? 53.676  77.036  89.317  1.00 311.51 ? 88  ARG A NE  1 
ATOM 686  C CZ  . ARG A 1 88  ? 53.972  77.801  90.358  1.00 311.51 ? 88  ARG A CZ  1 
ATOM 687  N NH1 . ARG A 1 88  ? 55.088  78.511  90.400  1.00 311.51 ? 88  ARG A NH1 1 
ATOM 688  N NH2 . ARG A 1 88  ? 53.127  77.856  91.384  1.00 311.51 ? 88  ARG A NH2 1 
ATOM 689  N N   . ARG A 1 89  ? 52.643  71.577  88.000  1.00 308.71 ? 89  ARG A N   1 
ATOM 690  C CA  . ARG A 1 89  ? 52.750  70.240  88.576  1.00 308.71 ? 89  ARG A CA  1 
ATOM 691  C C   . ARG A 1 89  ? 52.592  69.154  87.520  1.00 308.71 ? 89  ARG A C   1 
ATOM 692  O O   . ARG A 1 89  ? 53.115  68.047  87.691  1.00 308.71 ? 89  ARG A O   1 
ATOM 693  C CB  . ARG A 1 89  ? 51.712  70.058  89.684  1.00 308.71 ? 89  ARG A CB  1 
ATOM 694  C CG  . ARG A 1 89  ? 52.208  70.437  91.069  1.00 308.71 ? 89  ARG A CG  1 
ATOM 695  C CD  . ARG A 1 89  ? 53.251  69.445  91.557  1.00 308.71 ? 89  ARG A CD  1 
ATOM 696  N NE  . ARG A 1 89  ? 53.819  69.827  92.845  1.00 308.71 ? 89  ARG A NE  1 
ATOM 697  C CZ  . ARG A 1 89  ? 54.748  69.132  93.487  1.00 308.71 ? 89  ARG A CZ  1 
ATOM 698  N NH1 . ARG A 1 89  ? 55.234  68.006  92.992  1.00 308.71 ? 89  ARG A NH1 1 
ATOM 699  N NH2 . ARG A 1 89  ? 55.200  69.579  94.656  1.00 308.71 ? 89  ARG A NH2 1 
ATOM 700  N N   . GLU A 1 90  ? 51.873  69.443  86.431  1.00 313.36 ? 90  GLU A N   1 
ATOM 701  C CA  . GLU A 1 90  ? 51.673  68.436  85.394  1.00 313.36 ? 90  GLU A CA  1 
ATOM 702  C C   . GLU A 1 90  ? 52.986  68.067  84.715  1.00 313.36 ? 90  GLU A C   1 
ATOM 703  O O   . GLU A 1 90  ? 53.268  66.882  84.503  1.00 313.36 ? 90  GLU A O   1 
ATOM 704  C CB  . GLU A 1 90  ? 50.659  68.933  84.364  1.00 313.36 ? 90  GLU A CB  1 
ATOM 705  C CG  . GLU A 1 90  ? 50.337  67.922  83.275  1.00 313.36 ? 90  GLU A CG  1 
ATOM 706  C CD  . GLU A 1 90  ? 49.679  66.665  83.815  1.00 313.36 ? 90  GLU A CD  1 
ATOM 707  O OE1 . GLU A 1 90  ? 48.989  66.749  84.853  1.00 313.36 ? 90  GLU A OE1 1 
ATOM 708  O OE2 . GLU A 1 90  ? 49.854  65.591  83.202  1.00 313.36 ? 90  GLU A OE2 1 
ATOM 709  N N   . VAL A 1 91  ? 53.804  69.064  84.367  1.00 308.67 ? 91  VAL A N   1 
ATOM 710  C CA  . VAL A 1 91  ? 55.095  68.767  83.756  1.00 308.67 ? 91  VAL A CA  1 
ATOM 711  C C   . VAL A 1 91  ? 56.037  68.130  84.771  1.00 308.67 ? 91  VAL A C   1 
ATOM 712  O O   . VAL A 1 91  ? 56.914  67.340  84.401  1.00 308.67 ? 91  VAL A O   1 
ATOM 713  C CB  . VAL A 1 91  ? 55.705  70.033  83.124  1.00 308.67 ? 91  VAL A CB  1 
ATOM 714  C CG1 . VAL A 1 91  ? 54.773  70.594  82.060  1.00 308.67 ? 91  VAL A CG1 1 
ATOM 715  C CG2 . VAL A 1 91  ? 56.004  71.081  84.181  1.00 308.67 ? 91  VAL A CG2 1 
ATOM 716  N N   . LYS A 1 92  ? 55.880  68.457  86.058  1.00 298.20 ? 92  LYS A N   1 
ATOM 717  C CA  . LYS A 1 92  ? 56.698  67.826  87.090  1.00 298.20 ? 92  LYS A CA  1 
ATOM 718  C C   . LYS A 1 92  ? 56.473  66.319  87.126  1.00 298.20 ? 92  LYS A C   1 
ATOM 719  O O   . LYS A 1 92  ? 57.409  65.549  87.372  1.00 298.20 ? 92  LYS A O   1 
ATOM 720  C CB  . LYS A 1 92  ? 56.395  68.447  88.454  1.00 298.20 ? 92  LYS A CB  1 
ATOM 721  C CG  . LYS A 1 92  ? 56.875  69.881  88.606  1.00 298.20 ? 92  LYS A CG  1 
ATOM 722  C CD  . LYS A 1 92  ? 56.287  70.532  89.847  1.00 298.20 ? 92  LYS A CD  1 
ATOM 723  C CE  . LYS A 1 92  ? 56.690  71.994  89.946  1.00 298.20 ? 92  LYS A CE  1 
ATOM 724  N NZ  . LYS A 1 92  ? 56.077  72.664  91.127  1.00 298.20 ? 92  LYS A NZ  1 
ATOM 725  N N   . ASN A 1 93  ? 55.234  65.881  86.890  1.00 303.54 ? 93  ASN A N   1 
ATOM 726  C CA  . ASN A 1 93  ? 54.943  64.451  86.864  1.00 303.54 ? 93  ASN A CA  1 
ATOM 727  C C   . ASN A 1 93  ? 55.660  63.760  85.710  1.00 303.54 ? 93  ASN A C   1 
ATOM 728  O O   . ASN A 1 93  ? 56.243  62.685  85.888  1.00 303.54 ? 93  ASN A O   1 
ATOM 729  C CB  . ASN A 1 93  ? 53.434  64.227  86.770  1.00 303.54 ? 93  ASN A CB  1 
ATOM 730  C CG  . ASN A 1 93  ? 53.056  62.761  86.838  1.00 303.54 ? 93  ASN A CG  1 
ATOM 731  O OD1 . ASN A 1 93  ? 53.748  61.958  87.464  1.00 303.54 ? 93  ASN A OD1 1 
ATOM 732  N ND2 . ASN A 1 93  ? 51.957  62.402  86.186  1.00 303.54 ? 93  ASN A ND2 1 
ATOM 733  N N   . TYR A 1 94  ? 55.623  64.360  84.518  1.00 308.17 ? 94  TYR A N   1 
ATOM 734  C CA  . TYR A 1 94  ? 56.267  63.746  83.360  1.00 308.17 ? 94  TYR A CA  1 
ATOM 735  C C   . TYR A 1 94  ? 57.786  63.822  83.457  1.00 308.17 ? 94  TYR A C   1 
ATOM 736  O O   . TYR A 1 94  ? 58.483  62.865  83.101  1.00 308.17 ? 94  TYR A O   1 
ATOM 737  C CB  . TYR A 1 94  ? 55.778  64.414  82.076  1.00 308.17 ? 94  TYR A CB  1 
ATOM 738  C CG  . TYR A 1 94  ? 54.310  64.193  81.795  1.00 308.17 ? 94  TYR A CG  1 
ATOM 739  C CD1 . TYR A 1 94  ? 53.651  63.071  82.282  1.00 308.17 ? 94  TYR A CD1 1 
ATOM 740  C CD2 . TYR A 1 94  ? 53.582  65.106  81.044  1.00 308.17 ? 94  TYR A CD2 1 
ATOM 741  C CE1 . TYR A 1 94  ? 52.308  62.865  82.027  1.00 308.17 ? 94  TYR A CE1 1 
ATOM 742  C CE2 . TYR A 1 94  ? 52.239  64.908  80.784  1.00 308.17 ? 94  TYR A CE2 1 
ATOM 743  C CZ  . TYR A 1 94  ? 51.607  63.787  81.279  1.00 308.17 ? 94  TYR A CZ  1 
ATOM 744  O OH  . TYR A 1 94  ? 50.271  63.586  81.023  1.00 308.17 ? 94  TYR A OH  1 
ATOM 745  N N   . VAL A 1 95  ? 58.317  64.953  83.929  1.00 293.93 ? 95  VAL A N   1 
ATOM 746  C CA  . VAL A 1 95  ? 59.765  65.127  84.001  1.00 293.93 ? 95  VAL A CA  1 
ATOM 747  C C   . VAL A 1 95  ? 60.384  64.126  84.969  1.00 293.93 ? 95  VAL A C   1 
ATOM 748  O O   . VAL A 1 95  ? 61.415  63.511  84.672  1.00 293.93 ? 95  VAL A O   1 
ATOM 749  C CB  . VAL A 1 95  ? 60.108  66.579  84.384  1.00 293.93 ? 95  VAL A CB  1 
ATOM 750  C CG1 . VAL A 1 95  ? 61.548  66.682  84.853  1.00 293.93 ? 95  VAL A CG1 1 
ATOM 751  C CG2 . VAL A 1 95  ? 59.871  67.507  83.202  1.00 293.93 ? 95  VAL A CG2 1 
ATOM 752  N N   . LEU A 1 96  ? 59.765  63.938  86.137  1.00 286.95 ? 96  LEU A N   1 
ATOM 753  C CA  . LEU A 1 96  ? 60.322  63.019  87.125  1.00 286.95 ? 96  LEU A CA  1 
ATOM 754  C C   . LEU A 1 96  ? 60.162  61.564  86.702  1.00 286.95 ? 96  LEU A C   1 
ATOM 755  O O   . LEU A 1 96  ? 60.790  60.677  87.292  1.00 286.95 ? 96  LEU A O   1 
ATOM 756  C CB  . LEU A 1 96  ? 59.668  63.255  88.486  1.00 286.95 ? 96  LEU A CB  1 
ATOM 757  C CG  . LEU A 1 96  ? 60.572  63.871  89.555  1.00 286.95 ? 96  LEU A CG  1 
ATOM 758  C CD1 . LEU A 1 96  ? 61.362  65.038  88.986  1.00 286.95 ? 96  LEU A CD1 1 
ATOM 759  C CD2 . LEU A 1 96  ? 59.750  64.312  90.756  1.00 286.95 ? 96  LEU A CD2 1 
ATOM 760  N N   . HIS A 1 97  ? 59.338  61.296  85.692  1.00 294.93 ? 97  HIS A N   1 
ATOM 761  C CA  . HIS A 1 97  ? 59.172  59.950  85.162  1.00 294.93 ? 97  HIS A CA  1 
ATOM 762  C C   . HIS A 1 97  ? 59.869  59.759  83.821  1.00 294.93 ? 97  HIS A C   1 
ATOM 763  O O   . HIS A 1 97  ? 59.920  58.630  83.320  1.00 294.93 ? 97  HIS A O   1 
ATOM 764  C CB  . HIS A 1 97  ? 57.683  59.617  85.019  1.00 294.93 ? 97  HIS A CB  1 
ATOM 765  C CG  . HIS A 1 97  ? 56.918  59.688  86.304  1.00 294.93 ? 97  HIS A CG  1 
ATOM 766  N ND1 . HIS A 1 97  ? 57.527  59.867  87.528  1.00 294.93 ? 97  HIS A ND1 1 
ATOM 767  C CD2 . HIS A 1 97  ? 55.590  59.603  86.555  1.00 294.93 ? 97  HIS A CD2 1 
ATOM 768  C CE1 . HIS A 1 97  ? 56.607  59.891  88.476  1.00 294.93 ? 97  HIS A CE1 1 
ATOM 769  N NE2 . HIS A 1 97  ? 55.424  59.733  87.912  1.00 294.93 ? 97  HIS A NE2 1 
ATOM 770  N N   . THR A 1 98  ? 60.404  60.831  83.234  1.00 295.82 ? 98  THR A N   1 
ATOM 771  C CA  . THR A 1 98  ? 61.069  60.719  81.940  1.00 295.82 ? 98  THR A CA  1 
ATOM 772  C C   . THR A 1 98  ? 62.454  60.097  82.079  1.00 295.82 ? 98  THR A C   1 
ATOM 773  O O   . THR A 1 98  ? 62.904  59.365  81.190  1.00 295.82 ? 98  THR A O   1 
ATOM 774  C CB  . THR A 1 98  ? 61.163  62.097  81.283  1.00 295.82 ? 98  THR A CB  1 
ATOM 775  O OG1 . THR A 1 98  ? 59.858  62.684  81.214  1.00 295.82 ? 98  THR A OG1 1 
ATOM 776  C CG2 . THR A 1 98  ? 61.737  61.986  79.878  1.00 295.82 ? 98  THR A CG2 1 
ATOM 777  N N   . LEU A 1 99  ? 63.140  60.373  83.186  1.00 275.40 ? 99  LEU A N   1 
ATOM 778  C CA  . LEU A 1 99  ? 64.486  59.856  83.384  1.00 275.40 ? 99  LEU A CA  1 
ATOM 779  C C   . LEU A 1 99  ? 64.480  58.333  83.454  1.00 275.40 ? 99  LEU A C   1 
ATOM 780  O O   . LEU A 1 99  ? 63.547  57.711  83.970  1.00 275.40 ? 99  LEU A O   1 
ATOM 781  C CB  . LEU A 1 99  ? 65.103  60.450  84.652  1.00 275.40 ? 99  LEU A CB  1 
ATOM 782  C CG  . LEU A 1 99  ? 64.176  60.781  85.826  1.00 275.40 ? 99  LEU A CG  1 
ATOM 783  C CD1 . LEU A 1 99  ? 63.771  59.531  86.593  1.00 275.40 ? 99  LEU A CD1 1 
ATOM 784  C CD2 . LEU A 1 99  ? 64.831  61.793  86.756  1.00 275.40 ? 99  LEU A CD2 1 
ATOM 785  N N   . GLY A 1 100 ? 65.539  57.731  82.912  1.00 274.34 ? 100 GLY A N   1 
ATOM 786  C CA  . GLY A 1 100 ? 65.650  56.293  82.830  1.00 274.34 ? 100 GLY A CA  1 
ATOM 787  C C   . GLY A 1 100 ? 65.002  55.670  81.613  1.00 274.34 ? 100 GLY A C   1 
ATOM 788  O O   . GLY A 1 100 ? 65.123  54.453  81.421  1.00 274.34 ? 100 GLY A O   1 
ATOM 789  N N   . THR A 1 101 ? 64.318  56.460  80.785  1.00 289.42 ? 101 THR A N   1 
ATOM 790  C CA  . THR A 1 101 ? 63.675  55.965  79.575  1.00 289.42 ? 101 THR A CA  1 
ATOM 791  C C   . THR A 1 101 ? 64.481  56.269  78.319  1.00 289.42 ? 101 THR A C   1 
ATOM 792  O O   . THR A 1 101 ? 63.997  56.023  77.209  1.00 289.42 ? 101 THR A O   1 
ATOM 793  C CB  . THR A 1 101 ? 62.267  56.550  79.446  1.00 289.42 ? 101 THR A CB  1 
ATOM 794  O OG1 . THR A 1 101 ? 62.347  57.978  79.351  1.00 289.42 ? 101 THR A OG1 1 
ATOM 795  C CG2 . THR A 1 101 ? 61.423  56.175  80.656  1.00 289.42 ? 101 THR A CG2 1 
ATOM 796  N N   . GLU A 1 102 ? 65.693  56.796  78.463  1.00 289.19 ? 102 GLU A N   1 
ATOM 797  C CA  . GLU A 1 102 ? 66.542  57.152  77.334  1.00 289.19 ? 102 GLU A CA  1 
ATOM 798  C C   . GLU A 1 102 ? 67.850  56.378  77.418  1.00 289.19 ? 102 GLU A C   1 
ATOM 799  O O   . GLU A 1 102 ? 68.429  56.244  78.502  1.00 289.19 ? 102 GLU A O   1 
ATOM 800  C CB  . GLU A 1 102 ? 66.820  58.657  77.309  1.00 289.19 ? 102 GLU A CB  1 
ATOM 801  C CG  . GLU A 1 102 ? 65.570  59.520  77.278  1.00 289.19 ? 102 GLU A CG  1 
ATOM 802  C CD  . GLU A 1 102 ? 65.885  61.001  77.186  1.00 289.19 ? 102 GLU A CD  1 
ATOM 803  O OE1 . GLU A 1 102 ? 67.069  61.347  76.984  1.00 289.19 ? 102 GLU A OE1 1 
ATOM 804  O OE2 . GLU A 1 102 ? 64.950  61.819  77.315  1.00 289.19 ? 102 GLU A OE2 1 
ATOM 805  N N   . THR A 1 103 ? 68.311  55.874  76.276  1.00 278.45 ? 103 THR A N   1 
ATOM 806  C CA  . THR A 1 103 ? 69.562  55.133  76.195  1.00 278.45 ? 103 THR A CA  1 
ATOM 807  C C   . THR A 1 103 ? 70.772  56.034  75.983  1.00 278.45 ? 103 THR A C   1 
ATOM 808  O O   . THR A 1 103 ? 71.905  55.541  76.003  1.00 278.45 ? 103 THR A O   1 
ATOM 809  C CB  . THR A 1 103 ? 69.491  54.098  75.068  1.00 278.45 ? 103 THR A CB  1 
ATOM 810  O OG1 . THR A 1 103 ? 69.258  54.762  73.819  1.00 278.45 ? 103 THR A OG1 1 
ATOM 811  C CG2 . THR A 1 103 ? 68.364  53.108  75.328  1.00 278.45 ? 103 THR A CG2 1 
ATOM 812  N N   . TYR A 1 104 ? 70.559  57.331  75.772  1.00 264.37 ? 104 TYR A N   1 
ATOM 813  C CA  . TYR A 1 104 ? 71.666  58.258  75.586  1.00 264.37 ? 104 TYR A CA  1 
ATOM 814  C C   . TYR A 1 104 ? 72.498  58.358  76.859  1.00 264.37 ? 104 TYR A C   1 
ATOM 815  O O   . TYR A 1 104 ? 71.960  58.380  77.970  1.00 264.37 ? 104 TYR A O   1 
ATOM 816  C CB  . TYR A 1 104 ? 71.135  59.638  75.197  1.00 264.37 ? 104 TYR A CB  1 
ATOM 817  C CG  . TYR A 1 104 ? 72.096  60.467  74.377  1.00 264.37 ? 104 TYR A CG  1 
ATOM 818  C CD1 . TYR A 1 104 ? 73.262  59.914  73.864  1.00 264.37 ? 104 TYR A CD1 1 
ATOM 819  C CD2 . TYR A 1 104 ? 71.837  61.807  74.117  1.00 264.37 ? 104 TYR A CD2 1 
ATOM 820  C CE1 . TYR A 1 104 ? 74.141  60.671  73.114  1.00 264.37 ? 104 TYR A CE1 1 
ATOM 821  C CE2 . TYR A 1 104 ? 72.709  62.571  73.368  1.00 264.37 ? 104 TYR A CE2 1 
ATOM 822  C CZ  . TYR A 1 104 ? 73.860  61.999  72.869  1.00 264.37 ? 104 TYR A CZ  1 
ATOM 823  O OH  . TYR A 1 104 ? 74.732  62.759  72.123  1.00 264.37 ? 104 TYR A OH  1 
ATOM 824  N N   . ARG A 1 105 ? 73.820  58.410  76.694  1.00 244.47 ? 105 ARG A N   1 
ATOM 825  C CA  . ARG A 1 105 ? 74.695  58.563  77.854  1.00 244.47 ? 105 ARG A CA  1 
ATOM 826  C C   . ARG A 1 105 ? 74.434  59.856  78.621  1.00 244.47 ? 105 ARG A C   1 
ATOM 827  O O   . ARG A 1 105 ? 74.339  59.792  79.860  1.00 244.47 ? 105 ARG A O   1 
ATOM 828  C CB  . ARG A 1 105 ? 76.165  58.448  77.423  1.00 244.47 ? 105 ARG A CB  1 
ATOM 829  C CG  . ARG A 1 105 ? 77.163  58.682  78.546  1.00 244.47 ? 105 ARG A CG  1 
ATOM 830  C CD  . ARG A 1 105 ? 77.040  57.632  79.644  1.00 244.47 ? 105 ARG A CD  1 
ATOM 831  N NE  . ARG A 1 105 ? 77.410  56.300  79.180  1.00 244.47 ? 105 ARG A NE  1 
ATOM 832  C CZ  . ARG A 1 105 ? 76.546  55.329  78.915  1.00 244.47 ? 105 ARG A CZ  1 
ATOM 833  N NH1 . ARG A 1 105 ? 75.243  55.502  79.066  1.00 244.47 ? 105 ARG A NH1 1 
ATOM 834  N NH2 . ARG A 1 105 ? 77.002  54.153  78.491  1.00 244.47 ? 105 ARG A NH2 1 
ATOM 835  N N   . PRO A 1 106 ? 74.311  61.027  77.995  1.00 257.71 ? 106 PRO A N   1 
ATOM 836  C CA  . PRO A 1 106 ? 73.771  62.185  78.709  1.00 257.71 ? 106 PRO A CA  1 
ATOM 837  C C   . PRO A 1 106 ? 72.249  62.165  78.709  1.00 257.71 ? 106 PRO A C   1 
ATOM 838  O O   . PRO A 1 106 ? 71.602  61.612  77.816  1.00 257.71 ? 106 PRO A O   1 
ATOM 839  C CB  . PRO A 1 106 ? 74.306  63.374  77.899  1.00 257.71 ? 106 PRO A CB  1 
ATOM 840  C CG  . PRO A 1 106 ? 74.378  62.853  76.520  1.00 257.71 ? 106 PRO A CG  1 
ATOM 841  C CD  . PRO A 1 106 ? 74.772  61.401  76.643  1.00 257.71 ? 106 PRO A CD  1 
ATOM 842  N N   . SER A 1 107 ? 71.681  62.785  79.737  1.00 265.23 ? 107 SER A N   1 
ATOM 843  C CA  . SER A 1 107 ? 70.237  62.827  79.919  1.00 265.23 ? 107 SER A CA  1 
ATOM 844  C C   . SER A 1 107 ? 69.705  64.155  79.396  1.00 265.23 ? 107 SER A C   1 
ATOM 845  O O   . SER A 1 107 ? 70.091  65.221  79.887  1.00 265.23 ? 107 SER A O   1 
ATOM 846  C CB  . SER A 1 107 ? 69.865  62.638  81.389  1.00 265.23 ? 107 SER A CB  1 
ATOM 847  O OG  . SER A 1 107 ? 68.463  62.722  81.573  1.00 265.23 ? 107 SER A OG  1 
ATOM 848  N N   . SER A 1 108 ? 68.826  64.084  78.394  1.00 280.33 ? 108 SER A N   1 
ATOM 849  C CA  . SER A 1 108 ? 68.232  65.293  77.835  1.00 280.33 ? 108 SER A CA  1 
ATOM 850  C C   . SER A 1 108 ? 67.370  66.019  78.858  1.00 280.33 ? 108 SER A C   1 
ATOM 851  O O   . SER A 1 108 ? 67.395  67.253  78.924  1.00 280.33 ? 108 SER A O   1 
ATOM 852  C CB  . SER A 1 108 ? 67.407  64.946  76.597  1.00 280.33 ? 108 SER A CB  1 
ATOM 853  O OG  . SER A 1 108 ? 68.159  64.159  75.691  1.00 280.33 ? 108 SER A OG  1 
ATOM 854  N N   . ALA A 1 109 ? 66.605  65.277  79.658  1.00 270.04 ? 109 ALA A N   1 
ATOM 855  C CA  . ALA A 1 109 ? 65.717  65.877  80.643  1.00 270.04 ? 109 ALA A CA  1 
ATOM 856  C C   . ALA A 1 109 ? 66.455  66.468  81.837  1.00 270.04 ? 109 ALA A C   1 
ATOM 857  O O   . ALA A 1 109 ? 65.859  67.258  82.576  1.00 270.04 ? 109 ALA A O   1 
ATOM 858  C CB  . ALA A 1 109 ? 64.702  64.840  81.132  1.00 270.04 ? 109 ALA A CB  1 
ATOM 859  N N   . SER A 1 110 ? 67.726  66.109  82.044  1.00 254.50 ? 110 SER A N   1 
ATOM 860  C CA  . SER A 1 110 ? 68.474  66.649  83.177  1.00 254.50 ? 110 SER A CA  1 
ATOM 861  C C   . SER A 1 110 ? 68.616  68.163  83.079  1.00 254.50 ? 110 SER A C   1 
ATOM 862  O O   . SER A 1 110 ? 68.492  68.869  84.086  1.00 254.50 ? 110 SER A O   1 
ATOM 863  C CB  . SER A 1 110 ? 69.846  65.984  83.268  1.00 254.50 ? 110 SER A CB  1 
ATOM 864  O OG  . SER A 1 110 ? 69.742  64.672  83.793  1.00 254.50 ? 110 SER A OG  1 
ATOM 865  N N   . GLN A 1 111 ? 68.882  68.678  81.876  1.00 261.63 ? 111 GLN A N   1 
ATOM 866  C CA  . GLN A 1 111 ? 68.892  70.124  81.683  1.00 261.63 ? 111 GLN A CA  1 
ATOM 867  C C   . GLN A 1 111 ? 67.519  70.729  81.946  1.00 261.63 ? 111 GLN A C   1 
ATOM 868  O O   . GLN A 1 111 ? 67.424  71.839  82.484  1.00 261.63 ? 111 GLN A O   1 
ATOM 869  C CB  . GLN A 1 111 ? 69.363  70.464  80.269  1.00 261.63 ? 111 GLN A CB  1 
ATOM 870  C CG  . GLN A 1 111 ? 70.814  70.100  79.982  1.00 261.63 ? 111 GLN A CG  1 
ATOM 871  C CD  . GLN A 1 111 ? 71.802  71.050  80.635  1.00 261.63 ? 111 GLN A CD  1 
ATOM 872  O OE1 . GLN A 1 111 ? 71.414  72.042  81.253  1.00 261.63 ? 111 GLN A OE1 1 
ATOM 873  N NE2 . GLN A 1 111 ? 73.088  70.753  80.496  1.00 261.63 ? 111 GLN A NE2 1 
ATOM 874  N N   . CYS A 1 112 ? 66.451  70.023  81.566  1.00 273.39 ? 112 CYS A N   1 
ATOM 875  C CA  . CYS A 1 112 ? 65.101  70.502  81.846  1.00 273.39 ? 112 CYS A CA  1 
ATOM 876  C C   . CYS A 1 112 ? 64.835  70.567  83.346  1.00 273.39 ? 112 CYS A C   1 
ATOM 877  O O   . CYS A 1 112 ? 64.130  71.468  83.816  1.00 273.39 ? 112 CYS A O   1 
ATOM 878  C CB  . CYS A 1 112 ? 64.074  69.604  81.157  1.00 273.39 ? 112 CYS A CB  1 
ATOM 879  S SG  . CYS A 1 112 ? 64.294  69.457  79.370  1.00 273.39 ? 112 CYS A SG  1 
ATOM 880  N N   . VAL A 1 113 ? 65.380  69.615  84.108  1.00 265.96 ? 113 VAL A N   1 
ATOM 881  C CA  . VAL A 1 113 ? 65.198  69.621  85.559  1.00 265.96 ? 113 VAL A CA  1 
ATOM 882  C C   . VAL A 1 113 ? 65.820  70.873  86.164  1.00 265.96 ? 113 VAL A C   1 
ATOM 883  O O   . VAL A 1 113 ? 65.249  71.501  87.063  1.00 265.96 ? 113 VAL A O   1 
ATOM 884  C CB  . VAL A 1 113 ? 65.789  68.342  86.182  1.00 265.96 ? 113 VAL A CB  1 
ATOM 885  C CG1 . VAL A 1 113 ? 65.686  68.393  87.700  1.00 265.96 ? 113 VAL A CG1 1 
ATOM 886  C CG2 . VAL A 1 113 ? 65.082  67.110  85.643  1.00 265.96 ? 113 VAL A CG2 1 
ATOM 887  N N   . ALA A 1 114 ? 67.007  71.250  85.682  1.00 262.77 ? 114 ALA A N   1 
ATOM 888  C CA  . ALA A 1 114 ? 67.678  72.431  86.213  1.00 262.77 ? 114 ALA A CA  1 
ATOM 889  C C   . ALA A 1 114 ? 66.875  73.699  85.946  1.00 262.77 ? 114 ALA A C   1 
ATOM 890  O O   . ALA A 1 114 ? 66.753  74.559  86.825  1.00 262.77 ? 114 ALA A O   1 
ATOM 891  C CB  . ALA A 1 114 ? 69.079  72.551  85.616  1.00 262.77 ? 114 ALA A CB  1 
ATOM 892  N N   . GLY A 1 115 ? 66.321  73.832  84.740  1.00 276.09 ? 115 GLY A N   1 
ATOM 893  C CA  . GLY A 1 115 ? 65.656  75.073  84.374  1.00 276.09 ? 115 GLY A CA  1 
ATOM 894  C C   . GLY A 1 115 ? 64.410  75.354  85.191  1.00 276.09 ? 115 GLY A C   1 
ATOM 895  O O   . GLY A 1 115 ? 64.196  76.484  85.641  1.00 276.09 ? 115 GLY A O   1 
ATOM 896  N N   . ILE A 1 116 ? 63.569  74.338  85.392  1.00 279.62 ? 116 ILE A N   1 
ATOM 897  C CA  . ILE A 1 116 ? 62.333  74.542  86.142  1.00 279.62 ? 116 ILE A CA  1 
ATOM 898  C C   . ILE A 1 116 ? 62.637  74.876  87.598  1.00 279.62 ? 116 ILE A C   1 
ATOM 899  O O   . ILE A 1 116 ? 62.016  75.770  88.186  1.00 279.62 ? 116 ILE A O   1 
ATOM 900  C CB  . ILE A 1 116 ? 61.414  73.311  86.012  1.00 279.62 ? 116 ILE A CB  1 
ATOM 901  C CG1 . ILE A 1 116 ? 60.197  73.449  86.930  1.00 279.62 ? 116 ILE A CG1 1 
ATOM 902  C CG2 . ILE A 1 116 ? 62.172  72.025  86.306  1.00 279.62 ? 116 ILE A CG2 1 
ATOM 903  C CD1 . ILE A 1 116 ? 59.259  72.261  86.884  1.00 279.62 ? 116 ILE A CD1 1 
ATOM 904  N N   . ALA A 1 117 ? 63.603  74.179  88.199  1.00 272.11 ? 117 ALA A N   1 
ATOM 905  C CA  . ALA A 1 117 ? 63.936  74.400  89.600  1.00 272.11 ? 117 ALA A CA  1 
ATOM 906  C C   . ALA A 1 117 ? 64.637  75.730  89.844  1.00 272.11 ? 117 ALA A C   1 
ATOM 907  O O   . ALA A 1 117 ? 64.750  76.147  91.001  1.00 272.11 ? 117 ALA A O   1 
ATOM 908  C CB  . ALA A 1 117 ? 64.807  73.256  90.121  1.00 272.11 ? 117 ALA A CB  1 
ATOM 909  N N   . CYS A 1 118 ? 65.119  76.398  88.791  1.00 276.45 ? 118 CYS A N   1 
ATOM 910  C CA  . CYS A 1 118 ? 65.721  77.716  88.971  1.00 276.45 ? 118 CYS A CA  1 
ATOM 911  C C   . CYS A 1 118 ? 64.724  78.709  89.552  1.00 276.45 ? 118 CYS A C   1 
ATOM 912  O O   . CYS A 1 118 ? 65.114  79.623  90.287  1.00 276.45 ? 118 CYS A O   1 
ATOM 913  C CB  . CYS A 1 118 ? 66.273  78.234  87.643  1.00 276.45 ? 118 CYS A CB  1 
ATOM 914  S SG  . CYS A 1 118 ? 67.847  77.497  87.148  1.00 276.45 ? 118 CYS A SG  1 
ATOM 915  N N   . ALA A 1 119 ? 63.438  78.547  89.235  1.00 274.74 ? 119 ALA A N   1 
ATOM 916  C CA  . ALA A 1 119 ? 62.383  79.356  89.825  1.00 274.74 ? 119 ALA A CA  1 
ATOM 917  C C   . ALA A 1 119 ? 61.576  78.622  90.885  1.00 274.74 ? 119 ALA A C   1 
ATOM 918  O O   . ALA A 1 119 ? 60.948  79.279  91.721  1.00 274.74 ? 119 ALA A O   1 
ATOM 919  C CB  . ALA A 1 119 ? 61.427  79.866  88.737  1.00 274.74 ? 119 ALA A CB  1 
ATOM 920  N N   . GLU A 1 120 ? 61.574  77.287  90.871  1.00 278.40 ? 120 GLU A N   1 
ATOM 921  C CA  . GLU A 1 120 ? 60.801  76.530  91.851  1.00 278.40 ? 120 GLU A CA  1 
ATOM 922  C C   . GLU A 1 120 ? 61.449  76.554  93.231  1.00 278.40 ? 120 GLU A C   1 
ATOM 923  O O   . GLU A 1 120 ? 60.752  76.696  94.241  1.00 278.40 ? 120 GLU A O   1 
ATOM 924  C CB  . GLU A 1 120 ? 60.624  75.087  91.376  1.00 278.40 ? 120 GLU A CB  1 
ATOM 925  C CG  . GLU A 1 120 ? 59.629  74.925  90.240  1.00 278.40 ? 120 GLU A CG  1 
ATOM 926  C CD  . GLU A 1 120 ? 58.198  75.148  90.686  1.00 278.40 ? 120 GLU A CD  1 
ATOM 927  O OE1 . GLU A 1 120 ? 57.907  74.933  91.881  1.00 278.40 ? 120 GLU A OE1 1 
ATOM 928  O OE2 . GLU A 1 120 ? 57.364  75.540  89.843  1.00 278.40 ? 120 GLU A OE2 1 
ATOM 929  N N   . ILE A 1 121 ? 62.769  76.409  93.295  1.00 262.17 ? 121 ILE A N   1 
ATOM 930  C CA  . ILE A 1 121 ? 63.490  76.376  94.568  1.00 262.17 ? 121 ILE A CA  1 
ATOM 931  C C   . ILE A 1 121 ? 63.336  77.694  95.326  1.00 262.17 ? 121 ILE A C   1 
ATOM 932  O O   . ILE A 1 121 ? 63.016  77.662  96.523  1.00 262.17 ? 121 ILE A O   1 
ATOM 933  C CB  . ILE A 1 121 ? 64.972  76.023  94.359  1.00 262.17 ? 121 ILE A CB  1 
ATOM 934  C CG1 . ILE A 1 121 ? 65.110  74.612  93.782  1.00 262.17 ? 121 ILE A CG1 1 
ATOM 935  C CG2 . ILE A 1 121 ? 65.738  76.136  95.667  1.00 262.17 ? 121 ILE A CG2 1 
ATOM 936  C CD1 . ILE A 1 121 ? 64.573  73.525  94.687  1.00 262.17 ? 121 ILE A CD1 1 
ATOM 937  N N   . PRO A 1 122 ? 63.554  78.866  94.709  1.00 262.18 ? 122 PRO A N   1 
ATOM 938  C CA  . PRO A 1 122 ? 63.357  80.113  95.469  1.00 262.18 ? 122 PRO A CA  1 
ATOM 939  C C   . PRO A 1 122 ? 61.935  80.298  95.970  1.00 262.18 ? 122 PRO A C   1 
ATOM 940  O O   . PRO A 1 122 ? 61.744  80.871  97.050  1.00 262.18 ? 122 PRO A O   1 
ATOM 941  C CB  . PRO A 1 122 ? 63.752  81.208  94.467  1.00 262.18 ? 122 PRO A CB  1 
ATOM 942  C CG  . PRO A 1 122 ? 63.607  80.576  93.136  1.00 262.18 ? 122 PRO A CG  1 
ATOM 943  C CD  . PRO A 1 122 ? 64.010  79.151  93.336  1.00 262.18 ? 122 PRO A CD  1 
ATOM 944  N N   . VAL A 1 123 ? 60.933  79.832  95.224  1.00 269.40 ? 123 VAL A N   1 
ATOM 945  C CA  . VAL A 1 123 ? 59.550  79.946  95.671  1.00 269.40 ? 123 VAL A CA  1 
ATOM 946  C C   . VAL A 1 123 ? 59.106  78.733  96.483  1.00 269.40 ? 123 VAL A C   1 
ATOM 947  O O   . VAL A 1 123 ? 58.054  78.790  97.139  1.00 269.40 ? 123 VAL A O   1 
ATOM 948  C CB  . VAL A 1 123 ? 58.614  80.164  94.466  1.00 269.40 ? 123 VAL A CB  1 
ATOM 949  C CG1 . VAL A 1 123 ? 58.354  78.852  93.741  1.00 269.40 ? 123 VAL A CG1 1 
ATOM 950  C CG2 . VAL A 1 123 ? 57.311  80.826  94.899  1.00 269.40 ? 123 VAL A CG2 1 
ATOM 951  N N   . ASN A 1 124 ? 59.881  77.646  96.468  1.00 268.74 ? 124 ASN A N   1 
ATOM 952  C CA  . ASN A 1 124 ? 59.607  76.449  97.265  1.00 268.74 ? 124 ASN A CA  1 
ATOM 953  C C   . ASN A 1 124 ? 58.236  75.851  96.956  1.00 268.74 ? 124 ASN A C   1 
ATOM 954  O O   . ASN A 1 124 ? 57.553  75.345  97.849  1.00 268.74 ? 124 ASN A O   1 
ATOM 955  C CB  . ASN A 1 124 ? 59.737  76.738  98.764  1.00 268.74 ? 124 ASN A CB  1 
ATOM 956  C CG  . ASN A 1 124 ? 61.103  77.278  99.136  1.00 268.74 ? 124 ASN A CG  1 
ATOM 957  O OD1 . ASN A 1 124 ? 62.033  76.517  99.401  1.00 268.74 ? 124 ASN A OD1 1 
ATOM 958  N ND2 . ASN A 1 124 ? 61.230  78.600  99.159  1.00 268.74 ? 124 ASN A ND2 1 
ATOM 959  N N   . GLN A 1 125 ? 57.821  75.903  95.692  1.00 274.42 ? 125 GLN A N   1 
ATOM 960  C CA  . GLN A 1 125 ? 56.550  75.330  95.270  1.00 274.42 ? 125 GLN A CA  1 
ATOM 961  C C   . GLN A 1 125 ? 56.674  73.874  94.836  1.00 274.42 ? 125 GLN A C   1 
ATOM 962  O O   . GLN A 1 125 ? 55.659  73.253  94.503  1.00 274.42 ? 125 GLN A O   1 
ATOM 963  C CB  . GLN A 1 125 ? 55.949  76.159  94.130  1.00 274.42 ? 125 GLN A CB  1 
ATOM 964  C CG  . GLN A 1 125 ? 54.429  76.175  94.103  1.00 274.42 ? 125 GLN A CG  1 
ATOM 965  C CD  . GLN A 1 125 ? 53.833  76.963  95.254  1.00 274.42 ? 125 GLN A CD  1 
ATOM 966  O OE1 . GLN A 1 125 ? 54.493  77.817  95.847  1.00 274.42 ? 125 GLN A OE1 1 
ATOM 967  N NE2 . GLN A 1 125 ? 52.576  76.680  95.576  1.00 274.42 ? 125 GLN A NE2 1 
ATOM 968  N N   . TRP A 1 126 ? 57.884  73.318  94.830  1.00 277.79 ? 126 TRP A N   1 
ATOM 969  C CA  . TRP A 1 126 ? 58.121  71.915  94.490  1.00 277.79 ? 126 TRP A CA  1 
ATOM 970  C C   . TRP A 1 126 ? 58.972  71.309  95.599  1.00 277.79 ? 126 TRP A C   1 
ATOM 971  O O   . TRP A 1 126 ? 60.157  71.010  95.398  1.00 277.79 ? 126 TRP A O   1 
ATOM 972  C CB  . TRP A 1 126 ? 58.795  71.784  93.123  1.00 277.79 ? 126 TRP A CB  1 
ATOM 973  C CG  . TRP A 1 126 ? 58.768  70.396  92.553  1.00 277.79 ? 126 TRP A CG  1 
ATOM 974  C CD1 . TRP A 1 126 ? 58.191  69.291  93.109  1.00 277.79 ? 126 TRP A CD1 1 
ATOM 975  C CD2 . TRP A 1 126 ? 59.342  69.967  91.311  1.00 277.79 ? 126 TRP A CD2 1 
ATOM 976  N NE1 . TRP A 1 126 ? 58.372  68.201  92.291  1.00 277.79 ? 126 TRP A NE1 1 
ATOM 977  C CE2 . TRP A 1 126 ? 59.074  68.590  91.181  1.00 277.79 ? 126 TRP A CE2 1 
ATOM 978  C CE3 . TRP A 1 126 ? 60.055  70.613  90.297  1.00 277.79 ? 126 TRP A CE3 1 
ATOM 979  C CZ2 . TRP A 1 126 ? 59.496  67.849  90.081  1.00 277.79 ? 126 TRP A CZ2 1 
ATOM 980  C CZ3 . TRP A 1 126 ? 60.473  69.874  89.205  1.00 277.79 ? 126 TRP A CZ3 1 
ATOM 981  C CH2 . TRP A 1 126 ? 60.192  68.508  89.105  1.00 277.79 ? 126 TRP A CH2 1 
ATOM 982  N N   . PRO A 1 127 ? 58.395  71.113  96.791  1.00 274.29 ? 127 PRO A N   1 
ATOM 983  C CA  . PRO A 1 127 ? 59.205  70.657  97.931  1.00 274.29 ? 127 PRO A CA  1 
ATOM 984  C C   . PRO A 1 127 ? 59.552  69.179  97.905  1.00 274.29 ? 127 PRO A C   1 
ATOM 985  O O   . PRO A 1 127 ? 60.464  68.767  98.635  1.00 274.29 ? 127 PRO A O   1 
ATOM 986  C CB  . PRO A 1 127 ? 58.319  70.988  99.138  1.00 274.29 ? 127 PRO A CB  1 
ATOM 987  C CG  . PRO A 1 127 ? 56.932  70.854  98.606  1.00 274.29 ? 127 PRO A CG  1 
ATOM 988  C CD  . PRO A 1 127 ? 56.980  71.297  97.160  1.00 274.29 ? 127 PRO A CD  1 
ATOM 989  N N   . GLU A 1 128 ? 58.863  68.371  97.104  1.00 273.49 ? 128 GLU A N   1 
ATOM 990  C CA  . GLU A 1 128 ? 59.103  66.935  97.058  1.00 273.49 ? 128 GLU A CA  1 
ATOM 991  C C   . GLU A 1 128 ? 60.198  66.544  96.074  1.00 273.49 ? 128 GLU A C   1 
ATOM 992  O O   . GLU A 1 128 ? 60.444  65.348  95.888  1.00 273.49 ? 128 GLU A O   1 
ATOM 993  C CB  . GLU A 1 128 ? 57.805  66.194  96.715  1.00 273.49 ? 128 GLU A CB  1 
ATOM 994  C CG  . GLU A 1 128 ? 57.136  66.650  95.429  1.00 273.49 ? 128 GLU A CG  1 
ATOM 995  C CD  . GLU A 1 128 ? 57.524  65.805  94.232  1.00 273.49 ? 128 GLU A CD  1 
ATOM 996  O OE1 . GLU A 1 128 ? 58.127  64.730  94.428  1.00 273.49 ? 128 GLU A OE1 1 
ATOM 997  O OE2 . GLU A 1 128 ? 57.222  66.217  93.092  1.00 273.49 ? 128 GLU A OE2 1 
ATOM 998  N N   . LEU A 1 129 ? 60.856  67.519  95.440  1.00 261.44 ? 129 LEU A N   1 
ATOM 999  C CA  . LEU A 1 129 ? 61.910  67.206  94.479  1.00 261.44 ? 129 LEU A CA  1 
ATOM 1000 C C   . LEU A 1 129 ? 63.060  66.456  95.141  1.00 261.44 ? 129 LEU A C   1 
ATOM 1001 O O   . LEU A 1 129 ? 63.355  65.310  94.786  1.00 261.44 ? 129 LEU A O   1 
ATOM 1002 C CB  . LEU A 1 129 ? 62.421  68.492  93.828  1.00 261.44 ? 129 LEU A CB  1 
ATOM 1003 C CG  . LEU A 1 129 ? 62.357  68.600  92.303  1.00 261.44 ? 129 LEU A CG  1 
ATOM 1004 C CD1 . LEU A 1 129 ? 63.177  69.786  91.815  1.00 261.44 ? 129 LEU A CD1 1 
ATOM 1005 C CD2 . LEU A 1 129 ? 62.813  67.316  91.635  1.00 261.44 ? 129 LEU A CD2 1 
ATOM 1006 N N   . ILE A 1 130 ? 63.713  67.088  96.112  1.00 245.28 ? 130 ILE A N   1 
ATOM 1007 C CA  . ILE A 1 130 ? 64.923  66.557  96.741  1.00 245.28 ? 130 ILE A CA  1 
ATOM 1008 C C   . ILE A 1 130 ? 64.677  65.184  97.365  1.00 245.28 ? 130 ILE A C   1 
ATOM 1009 O O   . ILE A 1 130 ? 65.473  64.265  97.119  1.00 245.28 ? 130 ILE A O   1 
ATOM 1010 C CB  . ILE A 1 130 ? 65.491  67.549  97.773  1.00 245.28 ? 130 ILE A CB  1 
ATOM 1011 C CG1 . ILE A 1 130 ? 66.381  68.594  97.089  1.00 245.28 ? 130 ILE A CG1 1 
ATOM 1012 C CG2 . ILE A 1 130 ? 66.276  66.820  98.854  1.00 245.28 ? 130 ILE A CG2 1 
ATOM 1013 C CD1 . ILE A 1 130 ? 65.634  69.609  96.247  1.00 245.28 ? 130 ILE A CD1 1 
ATOM 1014 N N   . PRO A 1 131 ? 63.621  64.973  98.165  1.00 259.99 ? 131 PRO A N   1 
ATOM 1015 C CA  . PRO A 1 131 ? 63.390  63.615  98.689  1.00 259.99 ? 131 PRO A CA  1 
ATOM 1016 C C   . PRO A 1 131 ? 63.163  62.579  97.602  1.00 259.99 ? 131 PRO A C   1 
ATOM 1017 O O   . PRO A 1 131 ? 63.536  61.414  97.789  1.00 259.99 ? 131 PRO A O   1 
ATOM 1018 C CB  . PRO A 1 131 ? 62.152  63.782  99.582  1.00 259.99 ? 131 PRO A CB  1 
ATOM 1019 C CG  . PRO A 1 131 ? 61.496  65.023  99.103  1.00 259.99 ? 131 PRO A CG  1 
ATOM 1020 C CD  . PRO A 1 131 ? 62.615  65.919  98.683  1.00 259.99 ? 131 PRO A CD  1 
ATOM 1021 N N   . GLN A 1 132 ? 62.558  62.964  96.476  1.00 258.87 ? 132 GLN A N   1 
ATOM 1022 C CA  . GLN A 1 132 ? 62.344  62.018  95.385  1.00 258.87 ? 132 GLN A CA  1 
ATOM 1023 C C   . GLN A 1 132 ? 63.665  61.522  94.807  1.00 258.87 ? 132 GLN A C   1 
ATOM 1024 O O   . GLN A 1 132 ? 63.824  60.324  94.542  1.00 258.87 ? 132 GLN A O   1 
ATOM 1025 C CB  . GLN A 1 132 ? 61.489  62.666  94.295  1.00 258.87 ? 132 GLN A CB  1 
ATOM 1026 C CG  . GLN A 1 132 ? 61.690  62.086  92.901  1.00 258.87 ? 132 GLN A CG  1 
ATOM 1027 C CD  . GLN A 1 132 ? 61.073  60.710  92.732  1.00 258.87 ? 132 GLN A CD  1 
ATOM 1028 O OE1 . GLN A 1 132 ? 61.422  59.972  91.811  1.00 258.87 ? 132 GLN A OE1 1 
ATOM 1029 N NE2 . GLN A 1 132 ? 60.142  60.364  93.613  1.00 258.87 ? 132 GLN A NE2 1 
ATOM 1030 N N   . LEU A 1 133 ? 64.627  62.427  94.607  1.00 254.87 ? 133 LEU A N   1 
ATOM 1031 C CA  . LEU A 1 133 ? 65.900  62.034  94.008  1.00 254.87 ? 133 LEU A CA  1 
ATOM 1032 C C   . LEU A 1 133 ? 66.684  61.103  94.925  1.00 254.87 ? 133 LEU A C   1 
ATOM 1033 O O   . LEU A 1 133 ? 67.403  60.216  94.448  1.00 254.87 ? 133 LEU A O   1 
ATOM 1034 C CB  . LEU A 1 133 ? 66.730  63.272  93.664  1.00 254.87 ? 133 LEU A CB  1 
ATOM 1035 C CG  . LEU A 1 133 ? 66.478  63.936  92.306  1.00 254.87 ? 133 LEU A CG  1 
ATOM 1036 C CD1 . LEU A 1 133 ? 66.496  62.906  91.192  1.00 254.87 ? 133 LEU A CD1 1 
ATOM 1037 C CD2 . LEU A 1 133 ? 65.173  64.705  92.292  1.00 254.87 ? 133 LEU A CD2 1 
ATOM 1038 N N   . VAL A 1 134 ? 66.573  61.299  96.241  1.00 250.94 ? 134 VAL A N   1 
ATOM 1039 C CA  . VAL A 1 134 ? 67.288  60.443  97.185  1.00 250.94 ? 134 VAL A CA  1 
ATOM 1040 C C   . VAL A 1 134 ? 66.808  59.001  97.072  1.00 250.94 ? 134 VAL A C   1 
ATOM 1041 O O   . VAL A 1 134 ? 67.612  58.061  97.075  1.00 250.94 ? 134 VAL A O   1 
ATOM 1042 C CB  . VAL A 1 134 ? 67.132  60.982  98.619  1.00 250.94 ? 134 VAL A CB  1 
ATOM 1043 C CG1 . VAL A 1 134 ? 67.878  60.095  99.606  1.00 250.94 ? 134 VAL A CG1 1 
ATOM 1044 C CG2 . VAL A 1 134 ? 67.629  62.416  98.706  1.00 250.94 ? 134 VAL A CG2 1 
ATOM 1045 N N   . ALA A 1 135 ? 65.491  58.804  96.968  1.00 260.24 ? 135 ALA A N   1 
ATOM 1046 C CA  . ALA A 1 135 ? 64.949  57.454  96.855  1.00 260.24 ? 135 ALA A CA  1 
ATOM 1047 C C   . ALA A 1 135 ? 65.390  56.771  95.567  1.00 260.24 ? 135 ALA A C   1 
ATOM 1048 O O   . ALA A 1 135 ? 65.633  55.558  95.564  1.00 260.24 ? 135 ALA A O   1 
ATOM 1049 C CB  . ALA A 1 135 ? 63.423  57.491  96.940  1.00 260.24 ? 135 ALA A CB  1 
ATOM 1050 N N   . ASN A 1 136 ? 65.490  57.524  94.469  1.00 260.92 ? 136 ASN A N   1 
ATOM 1051 C CA  . ASN A 1 136 ? 65.893  56.933  93.196  1.00 260.92 ? 136 ASN A CA  1 
ATOM 1052 C C   . ASN A 1 136 ? 67.308  56.370  93.262  1.00 260.92 ? 136 ASN A C   1 
ATOM 1053 O O   . ASN A 1 136 ? 67.565  55.267  92.766  1.00 260.92 ? 136 ASN A O   1 
ATOM 1054 C CB  . ASN A 1 136 ? 65.783  57.972  92.081  1.00 260.92 ? 136 ASN A CB  1 
ATOM 1055 C CG  . ASN A 1 136 ? 64.352  58.391  91.818  1.00 260.92 ? 136 ASN A CG  1 
ATOM 1056 O OD1 . ASN A 1 136 ? 63.457  58.120  92.619  1.00 260.92 ? 136 ASN A OD1 1 
ATOM 1057 N ND2 . ASN A 1 136 ? 64.128  59.058  90.692  1.00 260.92 ? 136 ASN A ND2 1 
ATOM 1058 N N   . VAL A 1 137 ? 68.238  57.111  93.866  1.00 258.38 ? 137 VAL A N   1 
ATOM 1059 C CA  . VAL A 1 137 ? 69.618  56.643  93.954  1.00 258.38 ? 137 VAL A CA  1 
ATOM 1060 C C   . VAL A 1 137 ? 69.723  55.470  94.921  1.00 258.38 ? 137 VAL A C   1 
ATOM 1061 O O   . VAL A 1 137 ? 70.416  54.481  94.652  1.00 258.38 ? 137 VAL A O   1 
ATOM 1062 C CB  . VAL A 1 137 ? 70.551  57.797  94.360  1.00 258.38 ? 137 VAL A CB  1 
ATOM 1063 C CG1 . VAL A 1 137 ? 72.002  57.342  94.326  1.00 258.38 ? 137 VAL A CG1 1 
ATOM 1064 C CG2 . VAL A 1 137 ? 70.341  58.996  93.449  1.00 258.38 ? 137 VAL A CG2 1 
ATOM 1065 N N   . THR A 1 138 ? 69.036  55.561  96.060  1.00 260.03 ? 138 THR A N   1 
ATOM 1066 C CA  . THR A 1 138 ? 69.089  54.515  97.073  1.00 260.03 ? 138 THR A CA  1 
ATOM 1067 C C   . THR A 1 138 ? 68.362  53.243  96.652  1.00 260.03 ? 138 THR A C   1 
ATOM 1068 O O   . THR A 1 138 ? 68.591  52.189  97.256  1.00 260.03 ? 138 THR A O   1 
ATOM 1069 C CB  . THR A 1 138 ? 68.498  55.035  98.388  1.00 260.03 ? 138 THR A CB  1 
ATOM 1070 O OG1 . THR A 1 138 ? 68.857  56.411  98.562  1.00 260.03 ? 138 THR A OG1 1 
ATOM 1071 C CG2 . THR A 1 138 ? 69.030  54.236  99.572  1.00 260.03 ? 138 THR A CG2 1 
ATOM 1072 N N   . ASN A 1 139 ? 67.511  53.309  95.638  1.00 269.21 ? 139 ASN A N   1 
ATOM 1073 C CA  . ASN A 1 139 ? 66.760  52.136  95.205  1.00 269.21 ? 139 ASN A CA  1 
ATOM 1074 C C   . ASN A 1 139 ? 67.698  51.141  94.535  1.00 269.21 ? 139 ASN A C   1 
ATOM 1075 O O   . ASN A 1 139 ? 68.347  51.489  93.539  1.00 269.21 ? 139 ASN A O   1 
ATOM 1076 C CB  . ASN A 1 139 ? 65.646  52.553  94.247  1.00 269.21 ? 139 ASN A CB  1 
ATOM 1077 C CG  . ASN A 1 139 ? 64.590  51.476  94.068  1.00 269.21 ? 139 ASN A CG  1 
ATOM 1078 O OD1 . ASN A 1 139 ? 64.882  50.282  94.126  1.00 269.21 ? 139 ASN A OD1 1 
ATOM 1079 N ND2 . ASN A 1 139 ? 63.350  51.899  93.847  1.00 269.21 ? 139 ASN A ND2 1 
ATOM 1080 N N   . PRO A 1 140 ? 67.806  49.906  95.034  1.00 271.23 ? 140 PRO A N   1 
ATOM 1081 C CA  . PRO A 1 140 ? 68.690  48.921  94.393  1.00 271.23 ? 140 PRO A CA  1 
ATOM 1082 C C   . PRO A 1 140 ? 68.142  48.345  93.099  1.00 271.23 ? 140 PRO A C   1 
ATOM 1083 O O   . PRO A 1 140 ? 68.899  47.697  92.363  1.00 271.23 ? 140 PRO A O   1 
ATOM 1084 C CB  . PRO A 1 140 ? 68.822  47.831  95.463  1.00 271.23 ? 140 PRO A CB  1 
ATOM 1085 C CG  . PRO A 1 140 ? 67.543  47.914  96.227  1.00 271.23 ? 140 PRO A CG  1 
ATOM 1086 C CD  . PRO A 1 140 ? 67.172  49.373  96.254  1.00 271.23 ? 140 PRO A CD  1 
ATOM 1087 N N   . ASN A 1 141 ? 66.863  48.557  92.798  1.00 271.11 ? 141 ASN A N   1 
ATOM 1088 C CA  . ASN A 1 141 ? 66.248  48.036  91.585  1.00 271.11 ? 141 ASN A CA  1 
ATOM 1089 C C   . ASN A 1 141 ? 66.344  49.000  90.411  1.00 271.11 ? 141 ASN A C   1 
ATOM 1090 O O   . ASN A 1 141 ? 65.864  48.675  89.320  1.00 271.11 ? 141 ASN A O   1 
ATOM 1091 C CB  . ASN A 1 141 ? 64.778  47.692  91.847  1.00 271.11 ? 141 ASN A CB  1 
ATOM 1092 C CG  . ASN A 1 141 ? 64.602  46.732  93.006  1.00 271.11 ? 141 ASN A CG  1 
ATOM 1093 O OD1 . ASN A 1 141 ? 63.941  47.049  93.995  1.00 271.11 ? 141 ASN A OD1 1 
ATOM 1094 N ND2 . ASN A 1 141 ? 65.194  45.549  92.890  1.00 271.11 ? 141 ASN A ND2 1 
ATOM 1095 N N   . SER A 1 142 ? 66.944  50.171  90.608  1.00 255.13 ? 142 SER A N   1 
ATOM 1096 C CA  . SER A 1 142 ? 67.041  51.159  89.545  1.00 255.13 ? 142 SER A CA  1 
ATOM 1097 C C   . SER A 1 142 ? 68.000  50.699  88.453  1.00 255.13 ? 142 SER A C   1 
ATOM 1098 O O   . SER A 1 142 ? 69.005  50.032  88.713  1.00 255.13 ? 142 SER A O   1 
ATOM 1099 C CB  . SER A 1 142 ? 67.502  52.502  90.111  1.00 255.13 ? 142 SER A CB  1 
ATOM 1100 O OG  . SER A 1 142 ? 66.609  52.967  91.108  1.00 255.13 ? 142 SER A OG  1 
ATOM 1101 N N   . THR A 1 143 ? 67.677  51.066  87.216  1.00 247.01 ? 143 THR A N   1 
ATOM 1102 C CA  . THR A 1 143 ? 68.528  50.760  86.078  1.00 247.01 ? 143 THR A CA  1 
ATOM 1103 C C   . THR A 1 143 ? 69.712  51.725  86.032  1.00 247.01 ? 143 THR A C   1 
ATOM 1104 O O   . THR A 1 143 ? 69.742  52.749  86.720  1.00 247.01 ? 143 THR A O   1 
ATOM 1105 C CB  . THR A 1 143 ? 67.724  50.817  84.781  1.00 247.01 ? 143 THR A CB  1 
ATOM 1106 O OG1 . THR A 1 143 ? 67.166  52.127  84.620  1.00 247.01 ? 143 THR A OG1 1 
ATOM 1107 C CG2 . THR A 1 143 ? 66.600  49.793  84.808  1.00 247.01 ? 143 THR A CG2 1 
ATOM 1108 N N   . GLU A 1 144 ? 70.709  51.388  85.208  1.00 241.01 ? 144 GLU A N   1 
ATOM 1109 C CA  . GLU A 1 144 ? 71.887  52.242  85.084  1.00 241.01 ? 144 GLU A CA  1 
ATOM 1110 C C   . GLU A 1 144 ? 71.523  53.616  84.538  1.00 241.01 ? 144 GLU A C   1 
ATOM 1111 O O   . GLU A 1 144 ? 72.016  54.637  85.032  1.00 241.01 ? 144 GLU A O   1 
ATOM 1112 C CB  . GLU A 1 144 ? 72.929  51.574  84.187  1.00 241.01 ? 144 GLU A CB  1 
ATOM 1113 C CG  . GLU A 1 144 ? 74.166  52.422  83.939  1.00 241.01 ? 144 GLU A CG  1 
ATOM 1114 C CD  . GLU A 1 144 ? 75.046  51.866  82.836  1.00 241.01 ? 144 GLU A CD  1 
ATOM 1115 O OE1 . GLU A 1 144 ? 74.640  50.879  82.189  1.00 241.01 ? 144 GLU A OE1 1 
ATOM 1116 O OE2 . GLU A 1 144 ? 76.145  52.418  82.615  1.00 241.01 ? 144 GLU A OE2 1 
ATOM 1117 N N   . HIS A 1 145 ? 70.661  53.661  83.519  1.00 245.46 ? 145 HIS A N   1 
ATOM 1118 C CA  . HIS A 1 145 ? 70.284  54.936  82.918  1.00 245.46 ? 145 HIS A CA  1 
ATOM 1119 C C   . HIS A 1 145 ? 69.568  55.834  83.919  1.00 245.46 ? 145 HIS A C   1 
ATOM 1120 O O   . HIS A 1 145 ? 69.826  57.042  83.972  1.00 245.46 ? 145 HIS A O   1 
ATOM 1121 C CB  . HIS A 1 145 ? 69.409  54.697  81.688  1.00 245.46 ? 145 HIS A CB  1 
ATOM 1122 C CG  . HIS A 1 145 ? 70.060  53.851  80.640  1.00 245.46 ? 145 HIS A CG  1 
ATOM 1123 N ND1 . HIS A 1 145 ? 70.192  52.484  80.761  1.00 245.46 ? 145 HIS A ND1 1 
ATOM 1124 C CD2 . HIS A 1 145 ? 70.623  54.178  79.452  1.00 245.46 ? 145 HIS A CD2 1 
ATOM 1125 C CE1 . HIS A 1 145 ? 70.804  52.006  79.693  1.00 245.46 ? 145 HIS A CE1 1 
ATOM 1126 N NE2 . HIS A 1 145 ? 71.077  53.013  78.883  1.00 245.46 ? 145 HIS A NE2 1 
ATOM 1127 N N   . MET A 1 146 ? 68.662  55.265  84.717  1.00 248.97 ? 146 MET A N   1 
ATOM 1128 C CA  . MET A 1 146 ? 67.928  56.068  85.690  1.00 248.97 ? 146 MET A CA  1 
ATOM 1129 C C   . MET A 1 146 ? 68.848  56.578  86.793  1.00 248.97 ? 146 MET A C   1 
ATOM 1130 O O   . MET A 1 146 ? 68.658  57.689  87.302  1.00 248.97 ? 146 MET A O   1 
ATOM 1131 C CB  . MET A 1 146 ? 66.774  55.253  86.274  1.00 248.97 ? 146 MET A CB  1 
ATOM 1132 C CG  . MET A 1 146 ? 65.547  56.078  86.643  1.00 248.97 ? 146 MET A CG  1 
ATOM 1133 S SD  . MET A 1 146 ? 65.701  56.936  88.220  1.00 248.97 ? 146 MET A SD  1 
ATOM 1134 C CE  . MET A 1 146 ? 65.669  55.554  89.356  1.00 248.97 ? 146 MET A CE  1 
ATOM 1135 N N   . LYS A 1 147 ? 69.849  55.782  87.178  1.00 235.41 ? 147 LYS A N   1 
ATOM 1136 C CA  . LYS A 1 147 ? 70.789  56.220  88.206  1.00 235.41 ? 147 LYS A CA  1 
ATOM 1137 C C   . LYS A 1 147 ? 71.597  57.424  87.738  1.00 235.41 ? 147 LYS A C   1 
ATOM 1138 O O   . LYS A 1 147 ? 71.702  58.431  88.447  1.00 235.41 ? 147 LYS A O   1 
ATOM 1139 C CB  . LYS A 1 147 ? 71.719  55.070  88.596  1.00 235.41 ? 147 LYS A CB  1 
ATOM 1140 C CG  . LYS A 1 147 ? 71.063  53.981  89.428  1.00 235.41 ? 147 LYS A CG  1 
ATOM 1141 C CD  . LYS A 1 147 ? 72.080  52.927  89.840  1.00 235.41 ? 147 LYS A CD  1 
ATOM 1142 C CE  . LYS A 1 147 ? 71.451  51.864  90.725  1.00 235.41 ? 147 LYS A CE  1 
ATOM 1143 N NZ  . LYS A 1 147 ? 72.446  50.841  91.150  1.00 235.41 ? 147 LYS A NZ  1 
ATOM 1144 N N   . GLU A 1 148 ? 72.178  57.339  86.538  1.00 236.84 ? 148 GLU A N   1 
ATOM 1145 C CA  . GLU A 1 148 ? 73.037  58.417  86.058  1.00 236.84 ? 148 GLU A CA  1 
ATOM 1146 C C   . GLU A 1 148 ? 72.235  59.649  85.657  1.00 236.84 ? 148 GLU A C   1 
ATOM 1147 O O   . GLU A 1 148 ? 72.721  60.776  85.809  1.00 236.84 ? 148 GLU A O   1 
ATOM 1148 C CB  . GLU A 1 148 ? 73.897  57.927  84.891  1.00 236.84 ? 148 GLU A CB  1 
ATOM 1149 C CG  . GLU A 1 148 ? 73.119  57.356  83.712  1.00 236.84 ? 148 GLU A CG  1 
ATOM 1150 C CD  . GLU A 1 148 ? 72.735  58.412  82.693  1.00 236.84 ? 148 GLU A CD  1 
ATOM 1151 O OE1 . GLU A 1 148 ? 73.297  59.525  82.748  1.00 236.84 ? 148 GLU A OE1 1 
ATOM 1152 O OE2 . GLU A 1 148 ? 71.871  58.127  81.837  1.00 236.84 ? 148 GLU A OE2 1 
ATOM 1153 N N   . SER A 1 149 ? 71.018  59.460  85.137  1.00 237.04 ? 149 SER A N   1 
ATOM 1154 C CA  . SER A 1 149 ? 70.194  60.603  84.756  1.00 237.04 ? 149 SER A CA  1 
ATOM 1155 C C   . SER A 1 149 ? 69.858  61.468  85.964  1.00 237.04 ? 149 SER A C   1 
ATOM 1156 O O   . SER A 1 149 ? 69.883  62.701  85.879  1.00 237.04 ? 149 SER A O   1 
ATOM 1157 C CB  . SER A 1 149 ? 68.918  60.126  84.064  1.00 237.04 ? 149 SER A CB  1 
ATOM 1158 O OG  . SER A 1 149 ? 69.219  59.412  82.877  1.00 237.04 ? 149 SER A OG  1 
ATOM 1159 N N   . THR A 1 150 ? 69.531  60.839  87.096  1.00 230.14 ? 150 THR A N   1 
ATOM 1160 C CA  . THR A 1 150 ? 69.270  61.596  88.315  1.00 230.14 ? 150 THR A CA  1 
ATOM 1161 C C   . THR A 1 150 ? 70.519  62.325  88.794  1.00 230.14 ? 150 THR A C   1 
ATOM 1162 O O   . THR A 1 150 ? 70.449  63.497  89.181  1.00 230.14 ? 150 THR A O   1 
ATOM 1163 C CB  . THR A 1 150 ? 68.741  60.667  89.407  1.00 230.14 ? 150 THR A CB  1 
ATOM 1164 O OG1 . THR A 1 150 ? 69.667  59.592  89.613  1.00 230.14 ? 150 THR A OG1 1 
ATOM 1165 C CG2 . THR A 1 150 ? 67.386  60.098  89.012  1.00 230.14 ? 150 THR A CG2 1 
ATOM 1166 N N   . LEU A 1 151 ? 71.671  61.649  88.771  1.00 212.77 ? 151 LEU A N   1 
ATOM 1167 C CA  . LEU A 1 151 ? 72.915  62.292  89.185  1.00 212.77 ? 151 LEU A CA  1 
ATOM 1168 C C   . LEU A 1 151 ? 73.284  63.434  88.247  1.00 212.77 ? 151 LEU A C   1 
ATOM 1169 O O   . LEU A 1 151 ? 73.765  64.482  88.695  1.00 212.77 ? 151 LEU A O   1 
ATOM 1170 C CB  . LEU A 1 151 ? 74.043  61.264  89.251  1.00 212.77 ? 151 LEU A CB  1 
ATOM 1171 C CG  . LEU A 1 151 ? 73.841  60.086  90.207  1.00 212.77 ? 151 LEU A CG  1 
ATOM 1172 C CD1 . LEU A 1 151 ? 75.093  59.227  90.264  1.00 212.77 ? 151 LEU A CD1 1 
ATOM 1173 C CD2 . LEU A 1 151 ? 73.450  60.567  91.595  1.00 212.77 ? 151 LEU A CD2 1 
ATOM 1174 N N   . GLU A 1 152 ? 73.070  63.248  86.942  1.00 231.94 ? 152 GLU A N   1 
ATOM 1175 C CA  . GLU A 1 152 ? 73.347  64.315  85.986  1.00 231.94 ? 152 GLU A CA  1 
ATOM 1176 C C   . GLU A 1 152 ? 72.468  65.531  86.249  1.00 231.94 ? 152 GLU A C   1 
ATOM 1177 O O   . GLU A 1 152 ? 72.936  66.672  86.169  1.00 231.94 ? 152 GLU A O   1 
ATOM 1178 C CB  . GLU A 1 152 ? 73.148  63.805  84.559  1.00 231.94 ? 152 GLU A CB  1 
ATOM 1179 C CG  . GLU A 1 152 ? 73.392  64.853  83.488  1.00 231.94 ? 152 GLU A CG  1 
ATOM 1180 C CD  . GLU A 1 152 ? 73.183  64.319  82.085  1.00 231.94 ? 152 GLU A CD  1 
ATOM 1181 O OE1 . GLU A 1 152 ? 73.131  63.083  81.918  1.00 231.94 ? 152 GLU A OE1 1 
ATOM 1182 O OE2 . GLU A 1 152 ? 73.069  65.136  81.148  1.00 231.94 ? 152 GLU A OE2 1 
ATOM 1183 N N   . ALA A 1 153 ? 71.190  65.305  86.560  1.00 218.51 ? 153 ALA A N   1 
ATOM 1184 C CA  . ALA A 1 153 ? 70.308  66.413  86.904  1.00 218.51 ? 153 ALA A CA  1 
ATOM 1185 C C   . ALA A 1 153 ? 70.752  67.090  88.195  1.00 218.51 ? 153 ALA A C   1 
ATOM 1186 O O   . ALA A 1 153 ? 70.647  68.314  88.329  1.00 218.51 ? 153 ALA A O   1 
ATOM 1187 C CB  . ALA A 1 153 ? 68.866  65.919  87.020  1.00 218.51 ? 153 ALA A CB  1 
ATOM 1188 N N   . ILE A 1 154 ? 71.253  66.308  89.155  1.00 212.08 ? 154 ILE A N   1 
ATOM 1189 C CA  . ILE A 1 154 ? 71.706  66.877  90.423  1.00 212.08 ? 154 ILE A CA  1 
ATOM 1190 C C   . ILE A 1 154 ? 72.854  67.850  90.194  1.00 212.08 ? 154 ILE A C   1 
ATOM 1191 O O   . ILE A 1 154 ? 72.883  68.944  90.772  1.00 212.08 ? 154 ILE A O   1 
ATOM 1192 C CB  . ILE A 1 154 ? 72.099  65.755  91.403  1.00 212.08 ? 154 ILE A CB  1 
ATOM 1193 C CG1 . ILE A 1 154 ? 70.849  65.058  91.941  1.00 212.08 ? 154 ILE A CG1 1 
ATOM 1194 C CG2 . ILE A 1 154 ? 72.941  66.306  92.545  1.00 212.08 ? 154 ILE A CG2 1 
ATOM 1195 C CD1 . ILE A 1 154 ? 71.148  63.910  92.875  1.00 212.08 ? 154 ILE A CD1 1 
ATOM 1196 N N   . GLY A 1 155 ? 73.814  67.471  89.348  1.00 209.63 ? 155 GLY A N   1 
ATOM 1197 C CA  . GLY A 1 155 ? 74.919  68.369  89.052  1.00 209.63 ? 155 GLY A CA  1 
ATOM 1198 C C   . GLY A 1 155 ? 74.459  69.675  88.435  1.00 209.63 ? 155 GLY A C   1 
ATOM 1199 O O   . GLY A 1 155 ? 74.970  70.746  88.771  1.00 209.63 ? 155 GLY A O   1 
ATOM 1200 N N   . TYR A 1 156 ? 73.487  69.605  87.524  1.00 219.81 ? 156 TYR A N   1 
ATOM 1201 C CA  . TYR A 1 156 ? 72.939  70.816  86.926  1.00 219.81 ? 156 TYR A CA  1 
ATOM 1202 C C   . TYR A 1 156 ? 72.206  71.674  87.951  1.00 219.81 ? 156 TYR A C   1 
ATOM 1203 O O   . TYR A 1 156 ? 72.232  72.906  87.854  1.00 219.81 ? 156 TYR A O   1 
ATOM 1204 C CB  . TYR A 1 156 ? 72.007  70.453  85.770  1.00 219.81 ? 156 TYR A CB  1 
ATOM 1205 C CG  . TYR A 1 156 ? 72.695  69.734  84.632  1.00 219.81 ? 156 TYR A CG  1 
ATOM 1206 C CD1 . TYR A 1 156 ? 74.059  69.882  84.414  1.00 219.81 ? 156 TYR A CD1 1 
ATOM 1207 C CD2 . TYR A 1 156 ? 71.980  68.910  83.773  1.00 219.81 ? 156 TYR A CD2 1 
ATOM 1208 C CE1 . TYR A 1 156 ? 74.692  69.228  83.375  1.00 219.81 ? 156 TYR A CE1 1 
ATOM 1209 C CE2 . TYR A 1 156 ? 72.604  68.252  82.730  1.00 219.81 ? 156 TYR A CE2 1 
ATOM 1210 C CZ  . TYR A 1 156 ? 73.960  68.414  82.536  1.00 219.81 ? 156 TYR A CZ  1 
ATOM 1211 O OH  . TYR A 1 156 ? 74.587  67.762  81.501  1.00 219.81 ? 156 TYR A OH  1 
ATOM 1212 N N   . ILE A 1 157 ? 71.543  71.046  88.927  1.00 226.96 ? 157 ILE A N   1 
ATOM 1213 C CA  . ILE A 1 157 ? 70.801  71.800  89.938  1.00 226.96 ? 157 ILE A CA  1 
ATOM 1214 C C   . ILE A 1 157 ? 71.744  72.687  90.743  1.00 226.96 ? 157 ILE A C   1 
ATOM 1215 O O   . ILE A 1 157 ? 71.468  73.870  90.973  1.00 226.96 ? 157 ILE A O   1 
ATOM 1216 C CB  . ILE A 1 157 ? 70.015  70.842  90.851  1.00 226.96 ? 157 ILE A CB  1 
ATOM 1217 C CG1 . ILE A 1 157 ? 68.855  70.200  90.089  1.00 226.96 ? 157 ILE A CG1 1 
ATOM 1218 C CG2 . ILE A 1 157 ? 69.500  71.571  92.082  1.00 226.96 ? 157 ILE A CG2 1 
ATOM 1219 C CD1 . ILE A 1 157 ? 67.790  71.180  89.658  1.00 226.96 ? 157 ILE A CD1 1 
ATOM 1220 N N   . CYS A 1 158 ? 72.874  72.131  91.180  1.00 215.93 ? 158 CYS A N   1 
ATOM 1221 C CA  . CYS A 1 158 ? 73.802  72.877  92.019  1.00 215.93 ? 158 CYS A CA  1 
ATOM 1222 C C   . CYS A 1 158 ? 74.764  73.751  91.225  1.00 215.93 ? 158 CYS A C   1 
ATOM 1223 O O   . CYS A 1 158 ? 75.565  74.469  91.833  1.00 215.93 ? 158 CYS A O   1 
ATOM 1224 C CB  . CYS A 1 158 ? 74.598  71.911  92.901  1.00 215.93 ? 158 CYS A CB  1 
ATOM 1225 S SG  . CYS A 1 158 ? 75.390  70.566  91.997  1.00 215.93 ? 158 CYS A SG  1 
ATOM 1226 N N   . GLN A 1 159 ? 74.709  73.711  89.894  1.00 218.50 ? 159 GLN A N   1 
ATOM 1227 C CA  . GLN A 1 159 ? 75.602  74.512  89.064  1.00 218.50 ? 159 GLN A CA  1 
ATOM 1228 C C   . GLN A 1 159 ? 74.920  75.774  88.543  1.00 218.50 ? 159 GLN A C   1 
ATOM 1229 O O   . GLN A 1 159 ? 75.554  76.828  88.436  1.00 218.50 ? 159 GLN A O   1 
ATOM 1230 C CB  . GLN A 1 159 ? 76.126  73.669  87.897  1.00 218.50 ? 159 GLN A CB  1 
ATOM 1231 C CG  . GLN A 1 159 ? 77.053  74.411  86.946  1.00 218.50 ? 159 GLN A CG  1 
ATOM 1232 C CD  . GLN A 1 159 ? 77.556  73.530  85.820  1.00 218.50 ? 159 GLN A CD  1 
ATOM 1233 O OE1 . GLN A 1 159 ? 78.053  74.022  84.807  1.00 218.50 ? 159 GLN A OE1 1 
ATOM 1234 N NE2 . GLN A 1 159 ? 77.432  72.220  85.993  1.00 218.50 ? 159 GLN A NE2 1 
ATOM 1235 N N   . ASP A 1 160 ? 73.629  75.681  88.217  1.00 245.20 ? 160 ASP A N   1 
ATOM 1236 C CA  . ASP A 1 160 ? 72.918  76.821  87.649  1.00 245.20 ? 160 ASP A CA  1 
ATOM 1237 C C   . ASP A 1 160 ? 72.241  77.653  88.734  1.00 245.20 ? 160 ASP A C   1 
ATOM 1238 O O   . ASP A 1 160 ? 72.363  78.883  88.750  1.00 245.20 ? 160 ASP A O   1 
ATOM 1239 C CB  . ASP A 1 160 ? 71.891  76.335  86.623  1.00 245.20 ? 160 ASP A CB  1 
ATOM 1240 C CG  . ASP A 1 160 ? 71.467  77.423  85.654  1.00 245.20 ? 160 ASP A CG  1 
ATOM 1241 O OD1 . ASP A 1 160 ? 71.588  78.618  85.996  1.00 245.20 ? 160 ASP A OD1 1 
ATOM 1242 O OD2 . ASP A 1 160 ? 71.007  77.081  84.545  1.00 245.20 ? 160 ASP A OD2 1 
ATOM 1243 N N   . ILE A 1 161 ? 71.523  77.000  89.646  1.00 236.83 ? 161 ILE A N   1 
ATOM 1244 C CA  . ILE A 1 161 ? 70.765  77.701  90.676  1.00 236.83 ? 161 ILE A CA  1 
ATOM 1245 C C   . ILE A 1 161 ? 71.719  78.333  91.682  1.00 236.83 ? 161 ILE A C   1 
ATOM 1246 O O   . ILE A 1 161 ? 72.825  77.835  91.927  1.00 236.83 ? 161 ILE A O   1 
ATOM 1247 C CB  . ILE A 1 161 ? 69.772  76.739  91.358  1.00 236.83 ? 161 ILE A CB  1 
ATOM 1248 C CG1 . ILE A 1 161 ? 69.069  75.877  90.309  1.00 236.83 ? 161 ILE A CG1 1 
ATOM 1249 C CG2 . ILE A 1 161 ? 68.734  77.512  92.149  1.00 236.83 ? 161 ILE A CG2 1 
ATOM 1250 C CD1 . ILE A 1 161 ? 68.097  74.875  90.890  1.00 236.83 ? 161 ILE A CD1 1 
ATOM 1251 N N   . ASP A 1 162 ? 71.285  79.446  92.268  1.00 236.52 ? 162 ASP A N   1 
ATOM 1252 C CA  . ASP A 1 162 ? 72.110  80.172  93.222  1.00 236.52 ? 162 ASP A CA  1 
ATOM 1253 C C   . ASP A 1 162 ? 72.377  79.317  94.461  1.00 236.52 ? 162 ASP A C   1 
ATOM 1254 O O   . ASP A 1 162 ? 71.472  78.634  94.952  1.00 236.52 ? 162 ASP A O   1 
ATOM 1255 C CB  . ASP A 1 162 ? 71.426  81.481  93.616  1.00 236.52 ? 162 ASP A CB  1 
ATOM 1256 C CG  . ASP A 1 162 ? 71.602  81.816  95.083  1.00 236.52 ? 162 ASP A CG  1 
ATOM 1257 O OD1 . ASP A 1 162 ? 72.674  82.335  95.458  1.00 236.52 ? 162 ASP A OD1 1 
ATOM 1258 O OD2 . ASP A 1 162 ? 70.660  81.561  95.861  1.00 236.52 ? 162 ASP A OD2 1 
ATOM 1259 N N   . PRO A 1 163 ? 73.607  79.333  94.986  1.00 232.68 ? 163 PRO A N   1 
ATOM 1260 C CA  . PRO A 1 163 ? 73.934  78.491  96.150  1.00 232.68 ? 163 PRO A CA  1 
ATOM 1261 C C   . PRO A 1 163 ? 73.130  78.806  97.403  1.00 232.68 ? 163 PRO A C   1 
ATOM 1262 O O   . PRO A 1 163 ? 72.924  77.899  98.220  1.00 232.68 ? 163 PRO A O   1 
ATOM 1263 C CB  . PRO A 1 163 ? 75.429  78.762  96.372  1.00 232.68 ? 163 PRO A CB  1 
ATOM 1264 C CG  . PRO A 1 163 ? 75.680  80.082  95.718  1.00 232.68 ? 163 PRO A CG  1 
ATOM 1265 C CD  . PRO A 1 163 ? 74.764  80.123  94.533  1.00 232.68 ? 163 PRO A CD  1 
ATOM 1266 N N   . GLU A 1 164 ? 72.685  80.051  97.590  1.00 237.34 ? 164 GLU A N   1 
ATOM 1267 C CA  . GLU A 1 164 ? 71.950  80.401  98.803  1.00 237.34 ? 164 GLU A CA  1 
ATOM 1268 C C   . GLU A 1 164 ? 70.638  79.633  98.912  1.00 237.34 ? 164 GLU A C   1 
ATOM 1269 O O   . GLU A 1 164 ? 70.250  79.225  100.013 1.00 237.34 ? 164 GLU A O   1 
ATOM 1270 C CB  . GLU A 1 164 ? 71.694  81.908  98.845  1.00 237.34 ? 164 GLU A CB  1 
ATOM 1271 C CG  . GLU A 1 164 ? 70.962  82.396  100.088 1.00 237.34 ? 164 GLU A CG  1 
ATOM 1272 C CD  . GLU A 1 164 ? 69.455  82.423  99.915  1.00 237.34 ? 164 GLU A CD  1 
ATOM 1273 O OE1 . GLU A 1 164 ? 68.982  82.300  98.765  1.00 237.34 ? 164 GLU A OE1 1 
ATOM 1274 O OE2 . GLU A 1 164 ? 68.743  82.565  100.931 1.00 237.34 ? 164 GLU A OE2 1 
ATOM 1275 N N   . GLN A 1 165 ? 69.944  79.430  97.793  1.00 236.03 ? 165 GLN A N   1 
ATOM 1276 C CA  . GLN A 1 165 ? 68.658  78.745  97.796  1.00 236.03 ? 165 GLN A CA  1 
ATOM 1277 C C   . GLN A 1 165 ? 68.773  77.250  98.068  1.00 236.03 ? 165 GLN A C   1 
ATOM 1278 O O   . GLN A 1 165 ? 67.745  76.597  98.276  1.00 236.03 ? 165 GLN A O   1 
ATOM 1279 C CB  . GLN A 1 165 ? 67.947  78.975  96.460  1.00 236.03 ? 165 GLN A CB  1 
ATOM 1280 C CG  . GLN A 1 165 ? 67.634  80.435  96.171  1.00 236.03 ? 165 GLN A CG  1 
ATOM 1281 C CD  . GLN A 1 165 ? 67.242  80.673  94.726  1.00 236.03 ? 165 GLN A CD  1 
ATOM 1282 O OE1 . GLN A 1 165 ? 67.145  79.735  93.936  1.00 236.03 ? 165 GLN A OE1 1 
ATOM 1283 N NE2 . GLN A 1 165 ? 67.020  81.934  94.372  1.00 236.03 ? 165 GLN A NE2 1 
ATOM 1284 N N   . LEU A 1 166 ? 69.984  76.692  98.072  1.00 226.63 ? 166 LEU A N   1 
ATOM 1285 C CA  . LEU A 1 166 ? 70.189  75.270  98.325  1.00 226.63 ? 166 LEU A CA  1 
ATOM 1286 C C   . LEU A 1 166 ? 70.970  75.014  99.609  1.00 226.63 ? 166 LEU A C   1 
ATOM 1287 O O   . LEU A 1 166 ? 71.437  73.892  99.831  1.00 226.63 ? 166 LEU A O   1 
ATOM 1288 C CB  . LEU A 1 166 ? 70.898  74.610  97.140  1.00 226.63 ? 166 LEU A CB  1 
ATOM 1289 C CG  . LEU A 1 166 ? 70.114  74.377  95.844  1.00 226.63 ? 166 LEU A CG  1 
ATOM 1290 C CD1 . LEU A 1 166 ? 68.740  73.792  96.136  1.00 226.63 ? 166 LEU A CD1 1 
ATOM 1291 C CD2 . LEU A 1 166 ? 70.001  75.652  95.017  1.00 226.63 ? 166 LEU A CD2 1 
ATOM 1292 N N   . GLN A 1 167 ? 71.130  76.033  100.457 1.00 227.91 ? 167 GLN A N   1 
ATOM 1293 C CA  . GLN A 1 167 ? 71.869  75.852  101.703 1.00 227.91 ? 167 GLN A CA  1 
ATOM 1294 C C   . GLN A 1 167 ? 71.169  74.869  102.635 1.00 227.91 ? 167 GLN A C   1 
ATOM 1295 O O   . GLN A 1 167 ? 71.819  74.008  103.239 1.00 227.91 ? 167 GLN A O   1 
ATOM 1296 C CB  . GLN A 1 167 ? 72.062  77.200  102.400 1.00 227.91 ? 167 GLN A CB  1 
ATOM 1297 C CG  . GLN A 1 167 ? 72.870  78.217  101.605 1.00 227.91 ? 167 GLN A CG  1 
ATOM 1298 C CD  . GLN A 1 167 ? 74.351  77.893  101.554 1.00 227.91 ? 167 GLN A CD  1 
ATOM 1299 O OE1 . GLN A 1 167 ? 74.826  76.989  102.240 1.00 227.91 ? 167 GLN A OE1 1 
ATOM 1300 N NE2 . GLN A 1 167 ? 75.090  78.636  100.740 1.00 227.91 ? 167 GLN A NE2 1 
ATOM 1301 N N   . ASP A 1 168 ? 69.845  74.983  102.770 1.00 239.05 ? 168 ASP A N   1 
ATOM 1302 C CA  . ASP A 1 168 ? 69.109  74.158  103.724 1.00 239.05 ? 168 ASP A CA  1 
ATOM 1303 C C   . ASP A 1 168 ? 69.081  72.685  103.333 1.00 239.05 ? 168 ASP A C   1 
ATOM 1304 O O   . ASP A 1 168 ? 69.193  71.817  104.206 1.00 239.05 ? 168 ASP A O   1 
ATOM 1305 C CB  . ASP A 1 168 ? 67.681  74.684  103.880 1.00 239.05 ? 168 ASP A CB  1 
ATOM 1306 C CG  . ASP A 1 168 ? 66.967  74.843  102.551 1.00 239.05 ? 168 ASP A CG  1 
ATOM 1307 O OD1 . ASP A 1 168 ? 67.610  74.644  101.499 1.00 239.05 ? 168 ASP A OD1 1 
ATOM 1308 O OD2 . ASP A 1 168 ? 65.761  75.169  102.558 1.00 239.05 ? 168 ASP A OD2 1 
ATOM 1309 N N   . LYS A 1 169 ? 68.931  72.381  102.043 1.00 230.09 ? 169 LYS A N   1 
ATOM 1310 C CA  . LYS A 1 169 ? 68.741  71.016  101.571 1.00 230.09 ? 169 LYS A CA  1 
ATOM 1311 C C   . LYS A 1 169 ? 70.054  70.320  101.221 1.00 230.09 ? 169 LYS A C   1 
ATOM 1312 O O   . LYS A 1 169 ? 70.064  69.419  100.376 1.00 230.09 ? 169 LYS A O   1 
ATOM 1313 C CB  . LYS A 1 169 ? 67.799  71.004  100.366 1.00 230.09 ? 169 LYS A CB  1 
ATOM 1314 C CG  . LYS A 1 169 ? 66.389  71.481  100.679 1.00 230.09 ? 169 LYS A CG  1 
ATOM 1315 C CD  . LYS A 1 169 ? 65.535  71.556  99.425  1.00 230.09 ? 169 LYS A CD  1 
ATOM 1316 C CE  . LYS A 1 169 ? 66.090  72.570  98.437  1.00 230.09 ? 169 LYS A CE  1 
ATOM 1317 N NZ  . LYS A 1 169 ? 66.138  73.942  99.015  1.00 230.09 ? 169 LYS A NZ  1 
ATOM 1318 N N   . SER A 1 170 ? 71.160  70.721  101.850 1.00 229.31 ? 170 SER A N   1 
ATOM 1319 C CA  . SER A 1 170 ? 72.449  70.102  101.561 1.00 229.31 ? 170 SER A CA  1 
ATOM 1320 C C   . SER A 1 170 ? 72.560  68.689  102.125 1.00 229.31 ? 170 SER A C   1 
ATOM 1321 O O   . SER A 1 170 ? 73.173  67.823  101.490 1.00 229.31 ? 170 SER A O   1 
ATOM 1322 C CB  . SER A 1 170 ? 73.584  70.970  102.108 1.00 229.31 ? 170 SER A CB  1 
ATOM 1323 O OG  . SER A 1 170 ? 73.493  71.100  103.516 1.00 229.31 ? 170 SER A OG  1 
ATOM 1324 N N   . ASN A 1 171 ? 71.992  68.439  103.308 1.00 231.57 ? 171 ASN A N   1 
ATOM 1325 C CA  . ASN A 1 171 ? 72.172  67.142  103.958 1.00 231.57 ? 171 ASN A CA  1 
ATOM 1326 C C   . ASN A 1 171 ? 71.521  66.013  103.165 1.00 231.57 ? 171 ASN A C   1 
ATOM 1327 O O   . ASN A 1 171 ? 72.128  64.951  102.982 1.00 231.57 ? 171 ASN A O   1 
ATOM 1328 C CB  . ASN A 1 171 ? 71.617  67.188  105.382 1.00 231.57 ? 171 ASN A CB  1 
ATOM 1329 C CG  . ASN A 1 171 ? 70.243  67.821  105.453 1.00 231.57 ? 171 ASN A CG  1 
ATOM 1330 O OD1 . ASN A 1 171 ? 69.974  68.820  104.787 1.00 231.57 ? 171 ASN A OD1 1 
ATOM 1331 N ND2 . ASN A 1 171 ? 69.365  67.243  106.264 1.00 231.57 ? 171 ASN A ND2 1 
ATOM 1332 N N   . GLU A 1 172 ? 70.288  66.216  102.696 1.00 232.71 ? 172 GLU A N   1 
ATOM 1333 C CA  . GLU A 1 172 ? 69.595  65.156  101.968 1.00 232.71 ? 172 GLU A CA  1 
ATOM 1334 C C   . GLU A 1 172 ? 70.289  64.838  100.650 1.00 232.71 ? 172 GLU A C   1 
ATOM 1335 O O   . GLU A 1 172 ? 70.424  63.665  100.281 1.00 232.71 ? 172 GLU A O   1 
ATOM 1336 C CB  . GLU A 1 172 ? 68.138  65.548  101.720 1.00 232.71 ? 172 GLU A CB  1 
ATOM 1337 C CG  . GLU A 1 172 ? 67.349  65.875  102.975 1.00 232.71 ? 172 GLU A CG  1 
ATOM 1338 C CD  . GLU A 1 172 ? 67.491  67.325  103.388 1.00 232.71 ? 172 GLU A CD  1 
ATOM 1339 O OE1 . GLU A 1 172 ? 68.236  68.063  102.712 1.00 232.71 ? 172 GLU A OE1 1 
ATOM 1340 O OE2 . GLU A 1 172 ? 66.853  67.727  104.384 1.00 232.71 ? 172 GLU A OE2 1 
ATOM 1341 N N   . ILE A 1 173 ? 70.728  65.868  99.924  1.00 227.94 ? 173 ILE A N   1 
ATOM 1342 C CA  . ILE A 1 173 ? 71.371  65.650  98.631  1.00 227.94 ? 173 ILE A CA  1 
ATOM 1343 C C   . ILE A 1 173 ? 72.690  64.908  98.805  1.00 227.94 ? 173 ILE A C   1 
ATOM 1344 O O   . ILE A 1 173 ? 73.008  63.989  98.040  1.00 227.94 ? 173 ILE A O   1 
ATOM 1345 C CB  . ILE A 1 173 ? 71.563  66.990  97.898  1.00 227.94 ? 173 ILE A CB  1 
ATOM 1346 C CG1 . ILE A 1 173 ? 70.207  67.646  97.631  1.00 227.94 ? 173 ILE A CG1 1 
ATOM 1347 C CG2 . ILE A 1 173 ? 72.319  66.785  96.594  1.00 227.94 ? 173 ILE A CG2 1 
ATOM 1348 C CD1 . ILE A 1 173 ? 70.303  68.968  96.908  1.00 227.94 ? 173 ILE A CD1 1 
ATOM 1349 N N   . LEU A 1 174 ? 73.481  65.294  99.811  1.00 223.69 ? 174 LEU A N   1 
ATOM 1350 C CA  . LEU A 1 174 ? 74.762  64.631  100.036 1.00 223.69 ? 174 LEU A CA  1 
ATOM 1351 C C   . LEU A 1 174 ? 74.575  63.168  100.422 1.00 223.69 ? 174 LEU A C   1 
ATOM 1352 O O   . LEU A 1 174 ? 75.410  62.322  100.084 1.00 223.69 ? 174 LEU A O   1 
ATOM 1353 C CB  . LEU A 1 174 ? 75.567  65.369  101.104 1.00 223.69 ? 174 LEU A CB  1 
ATOM 1354 C CG  . LEU A 1 174 ? 76.697  66.246  100.560 1.00 223.69 ? 174 LEU A CG  1 
ATOM 1355 C CD1 . LEU A 1 174 ? 76.206  67.652  100.242 1.00 223.69 ? 174 LEU A CD1 1 
ATOM 1356 C CD2 . LEU A 1 174 ? 77.871  66.280  101.524 1.00 223.69 ? 174 LEU A CD2 1 
ATOM 1357 N N   . THR A 1 175 ? 73.494  62.852  101.137 1.00 232.83 ? 175 THR A N   1 
ATOM 1358 C CA  . THR A 1 175 ? 73.224  61.458  101.479 1.00 232.83 ? 175 THR A CA  1 
ATOM 1359 C C   . THR A 1 175 ? 72.971  60.627  100.227 1.00 232.83 ? 175 THR A C   1 
ATOM 1360 O O   . THR A 1 175 ? 73.425  59.481  100.129 1.00 232.83 ? 175 THR A O   1 
ATOM 1361 C CB  . THR A 1 175 ? 72.031  61.371  102.433 1.00 232.83 ? 175 THR A CB  1 
ATOM 1362 O OG1 . THR A 1 175 ? 72.287  62.171  103.595 1.00 232.83 ? 175 THR A OG1 1 
ATOM 1363 C CG2 . THR A 1 175 ? 71.792  59.931  102.862 1.00 232.83 ? 175 THR A CG2 1 
ATOM 1364 N N   . ALA A 1 176 ? 72.249  61.192  99.256  1.00 229.98 ? 176 ALA A N   1 
ATOM 1365 C CA  . ALA A 1 176 ? 71.951  60.461  98.028  1.00 229.98 ? 176 ALA A CA  1 
ATOM 1366 C C   . ALA A 1 176 ? 73.196  60.270  97.169  1.00 229.98 ? 176 ALA A C   1 
ATOM 1367 O O   . ALA A 1 176 ? 73.436  59.172  96.654  1.00 229.98 ? 176 ALA A O   1 
ATOM 1368 C CB  . ALA A 1 176 ? 70.865  61.189  97.237  1.00 229.98 ? 176 ALA A CB  1 
ATOM 1369 N N   . ILE A 1 177 ? 73.995  61.326  96.995  1.00 219.27 ? 177 ILE A N   1 
ATOM 1370 C CA  . ILE A 1 177 ? 75.133  61.245  96.084  1.00 219.27 ? 177 ILE A CA  1 
ATOM 1371 C C   . ILE A 1 177 ? 76.190  60.271  96.600  1.00 219.27 ? 177 ILE A C   1 
ATOM 1372 O O   . ILE A 1 177 ? 76.824  59.566  95.806  1.00 219.27 ? 177 ILE A O   1 
ATOM 1373 C CB  . ILE A 1 177 ? 75.723  62.645  95.830  1.00 219.27 ? 177 ILE A CB  1 
ATOM 1374 C CG1 . ILE A 1 177 ? 76.800  62.584  94.746  1.00 219.27 ? 177 ILE A CG1 1 
ATOM 1375 C CG2 . ILE A 1 177 ? 76.291  63.248  97.105  1.00 219.27 ? 177 ILE A CG2 1 
ATOM 1376 C CD1 . ILE A 1 177 ? 76.275  62.149  93.400  1.00 219.27 ? 177 ILE A CD1 1 
ATOM 1377 N N   . ILE A 1 178 ? 76.397  60.207  97.918  1.00 220.49 ? 178 ILE A N   1 
ATOM 1378 C CA  . ILE A 1 178 ? 77.353  59.256  98.476  1.00 220.49 ? 178 ILE A CA  1 
ATOM 1379 C C   . ILE A 1 178 ? 76.869  57.825  98.268  1.00 220.49 ? 178 ILE A C   1 
ATOM 1380 O O   . ILE A 1 178 ? 77.671  56.912  98.036  1.00 220.49 ? 178 ILE A O   1 
ATOM 1381 C CB  . ILE A 1 178 ? 77.607  59.567  99.963  1.00 220.49 ? 178 ILE A CB  1 
ATOM 1382 C CG1 . ILE A 1 178 ? 78.269  60.939  100.109 1.00 220.49 ? 178 ILE A CG1 1 
ATOM 1383 C CG2 . ILE A 1 178 ? 78.474  58.494  100.602 1.00 220.49 ? 178 ILE A CG2 1 
ATOM 1384 C CD1 . ILE A 1 178 ? 79.561  61.084  99.324  1.00 220.49 ? 178 ILE A CD1 1 
ATOM 1385 N N   . GLN A 1 179 ? 75.552  57.607  98.342  1.00 231.66 ? 179 GLN A N   1 
ATOM 1386 C CA  . GLN A 1 179 ? 75.007  56.271  98.117  1.00 231.66 ? 179 GLN A CA  1 
ATOM 1387 C C   . GLN A 1 179 ? 75.342  55.766  96.719  1.00 231.66 ? 179 GLN A C   1 
ATOM 1388 O O   . GLN A 1 179 ? 75.694  54.594  96.541  1.00 231.66 ? 179 GLN A O   1 
ATOM 1389 C CB  . GLN A 1 179 ? 73.494  56.278  98.338  1.00 231.66 ? 179 GLN A CB  1 
ATOM 1390 C CG  . GLN A 1 179 ? 72.792  54.997  97.911  1.00 231.66 ? 179 GLN A CG  1 
ATOM 1391 C CD  . GLN A 1 179 ? 73.268  53.781  98.681  1.00 231.66 ? 179 GLN A CD  1 
ATOM 1392 O OE1 . GLN A 1 179 ? 73.395  52.691  98.123  1.00 231.66 ? 179 GLN A OE1 1 
ATOM 1393 N NE2 . GLN A 1 179 ? 73.529  53.960  99.971  1.00 231.66 ? 179 GLN A NE2 1 
ATOM 1394 N N   . GLY A 1 180 ? 75.240  56.632  95.715  1.00 229.43 ? 180 GLY A N   1 
ATOM 1395 C CA  . GLY A 1 180 ? 75.652  56.280  94.375  1.00 229.43 ? 180 GLY A CA  1 
ATOM 1396 C C   . GLY A 1 180 ? 77.133  56.402  94.111  1.00 229.43 ? 180 GLY A C   1 
ATOM 1397 O O   . GLY A 1 180 ? 77.590  56.071  93.013  1.00 229.43 ? 180 GLY A O   1 
ATOM 1398 N N   . MET A 1 181 ? 77.902  56.870  95.093  1.00 218.86 ? 181 MET A N   1 
ATOM 1399 C CA  . MET A 1 181 ? 79.342  57.041  94.963  1.00 218.86 ? 181 MET A CA  1 
ATOM 1400 C C   . MET A 1 181 ? 80.129  55.850  95.493  1.00 218.86 ? 181 MET A C   1 
ATOM 1401 O O   . MET A 1 181 ? 81.363  55.871  95.454  1.00 218.86 ? 181 MET A O   1 
ATOM 1402 C CB  . MET A 1 181 ? 79.787  58.315  95.685  1.00 218.86 ? 181 MET A CB  1 
ATOM 1403 C CG  . MET A 1 181 ? 80.490  59.323  94.794  1.00 218.86 ? 181 MET A CG  1 
ATOM 1404 S SD  . MET A 1 181 ? 81.898  58.624  93.914  1.00 218.86 ? 181 MET A SD  1 
ATOM 1405 C CE  . MET A 1 181 ? 82.661  60.112  93.275  1.00 218.86 ? 181 MET A CE  1 
ATOM 1406 N N   . ARG A 1 182 ? 79.451  54.819  95.991  1.00 224.12 ? 182 ARG A N   1 
ATOM 1407 C CA  . ARG A 1 182 ? 80.145  53.668  96.550  1.00 224.12 ? 182 ARG A CA  1 
ATOM 1408 C C   . ARG A 1 182 ? 80.922  52.927  95.467  1.00 224.12 ? 182 ARG A C   1 
ATOM 1409 O O   . ARG A 1 182 ? 80.464  52.777  94.331  1.00 224.12 ? 182 ARG A O   1 
ATOM 1410 C CB  . ARG A 1 182 ? 79.155  52.718  97.224  1.00 224.12 ? 182 ARG A CB  1 
ATOM 1411 C CG  . ARG A 1 182 ? 78.181  53.397  98.174  1.00 224.12 ? 182 ARG A CG  1 
ATOM 1412 C CD  . ARG A 1 182 ? 78.892  54.146  99.294  1.00 224.12 ? 182 ARG A CD  1 
ATOM 1413 N NE  . ARG A 1 182 ? 79.530  53.248  100.250 1.00 224.12 ? 182 ARG A NE  1 
ATOM 1414 C CZ  . ARG A 1 182 ? 80.838  53.047  100.336 1.00 224.12 ? 182 ARG A CZ  1 
ATOM 1415 N NH1 . ARG A 1 182 ? 81.687  53.673  99.538  1.00 224.12 ? 182 ARG A NH1 1 
ATOM 1416 N NH2 . ARG A 1 182 ? 81.306  52.201  101.249 1.00 224.12 ? 182 ARG A NH2 1 
ATOM 1417 N N   . LYS A 1 183 ? 82.118  52.463  95.833  1.00 215.17 ? 183 LYS A N   1 
ATOM 1418 C CA  . LYS A 1 183 ? 82.972  51.725  94.911  1.00 215.17 ? 183 LYS A CA  1 
ATOM 1419 C C   . LYS A 1 183 ? 82.377  50.391  94.481  1.00 215.17 ? 183 LYS A C   1 
ATOM 1420 O O   . LYS A 1 183 ? 82.851  49.808  93.499  1.00 215.17 ? 183 LYS A O   1 
ATOM 1421 C CB  . LYS A 1 183 ? 84.350  51.495  95.539  1.00 215.17 ? 183 LYS A CB  1 
ATOM 1422 C CG  . LYS A 1 183 ? 84.310  50.890  96.932  1.00 215.17 ? 183 LYS A CG  1 
ATOM 1423 C CD  . LYS A 1 183 ? 85.711  50.731  97.501  1.00 215.17 ? 183 LYS A CD  1 
ATOM 1424 C CE  . LYS A 1 183 ? 85.668  50.283  98.952  1.00 215.17 ? 183 LYS A CE  1 
ATOM 1425 N NZ  . LYS A 1 183 ? 84.991  51.288  99.818  1.00 215.17 ? 183 LYS A NZ  1 
ATOM 1426 N N   . GLU A 1 184 ? 81.361  49.894  95.184  1.00 223.83 ? 184 GLU A N   1 
ATOM 1427 C CA  . GLU A 1 184 ? 80.695  48.651  94.816  1.00 223.83 ? 184 GLU A CA  1 
ATOM 1428 C C   . GLU A 1 184 ? 79.823  48.786  93.573  1.00 223.83 ? 184 GLU A C   1 
ATOM 1429 O O   . GLU A 1 184 ? 79.335  47.767  93.070  1.00 223.83 ? 184 GLU A O   1 
ATOM 1430 C CB  . GLU A 1 184 ? 79.847  48.140  95.986  1.00 223.83 ? 184 GLU A CB  1 
ATOM 1431 C CG  . GLU A 1 184 ? 80.650  47.616  97.171  1.00 223.83 ? 184 GLU A CG  1 
ATOM 1432 C CD  . GLU A 1 184 ? 81.241  48.723  98.026  1.00 223.83 ? 184 GLU A CD  1 
ATOM 1433 O OE1 . GLU A 1 184 ? 80.851  49.895  97.843  1.00 223.83 ? 184 GLU A OE1 1 
ATOM 1434 O OE2 . GLU A 1 184 ? 82.097  48.418  98.884  1.00 223.83 ? 184 GLU A OE2 1 
ATOM 1435 N N   . GLU A 1 185 ? 79.606  49.999  93.077  1.00 226.79 ? 185 GLU A N   1 
ATOM 1436 C CA  . GLU A 1 185 ? 78.797  50.185  91.877  1.00 226.79 ? 185 GLU A CA  1 
ATOM 1437 C C   . GLU A 1 185 ? 79.483  49.539  90.678  1.00 226.79 ? 185 GLU A C   1 
ATOM 1438 O O   . GLU A 1 185 ? 80.642  49.859  90.386  1.00 226.79 ? 185 GLU A O   1 
ATOM 1439 C CB  . GLU A 1 185 ? 78.563  51.671  91.617  1.00 226.79 ? 185 GLU A CB  1 
ATOM 1440 C CG  . GLU A 1 185 ? 78.032  51.989  90.226  1.00 226.79 ? 185 GLU A CG  1 
ATOM 1441 C CD  . GLU A 1 185 ? 76.619  51.483  90.000  1.00 226.79 ? 185 GLU A CD  1 
ATOM 1442 O OE1 . GLU A 1 185 ? 75.870  51.335  90.988  1.00 226.79 ? 185 GLU A OE1 1 
ATOM 1443 O OE2 . GLU A 1 185 ? 76.257  51.234  88.830  1.00 226.79 ? 185 GLU A OE2 1 
ATOM 1444 N N   . PRO A 1 186 ? 78.812  48.632  89.963  1.00 223.94 ? 186 PRO A N   1 
ATOM 1445 C CA  . PRO A 1 186 ? 79.458  47.982  88.811  1.00 223.94 ? 186 PRO A CA  1 
ATOM 1446 C C   . PRO A 1 186 ? 79.693  48.913  87.634  1.00 223.94 ? 186 PRO A C   1 
ATOM 1447 O O   . PRO A 1 186 ? 80.773  48.858  87.032  1.00 223.94 ? 186 PRO A O   1 
ATOM 1448 C CB  . PRO A 1 186 ? 78.476  46.860  88.440  1.00 223.94 ? 186 PRO A CB  1 
ATOM 1449 C CG  . PRO A 1 186 ? 77.593  46.692  89.645  1.00 223.94 ? 186 PRO A CG  1 
ATOM 1450 C CD  . PRO A 1 186 ? 77.491  48.053  90.253  1.00 223.94 ? 186 PRO A CD  1 
ATOM 1451 N N   . SER A 1 187 ? 78.727  49.759  87.284  1.00 222.82 ? 187 SER A N   1 
ATOM 1452 C CA  . SER A 1 187 ? 78.833  50.616  86.111  1.00 222.82 ? 187 SER A CA  1 
ATOM 1453 C C   . SER A 1 187 ? 79.783  51.775  86.382  1.00 222.82 ? 187 SER A C   1 
ATOM 1454 O O   . SER A 1 187 ? 79.667  52.456  87.406  1.00 222.82 ? 187 SER A O   1 
ATOM 1455 C CB  . SER A 1 187 ? 77.457  51.147  85.707  1.00 222.82 ? 187 SER A CB  1 
ATOM 1456 O OG  . SER A 1 187 ? 77.559  52.032  84.605  1.00 222.82 ? 187 SER A OG  1 
ATOM 1457 N N   . ASN A 1 188 ? 80.722  51.993  85.460  1.00 212.61 ? 188 ASN A N   1 
ATOM 1458 C CA  . ASN A 1 188 ? 81.655  53.106  85.578  1.00 212.61 ? 188 ASN A CA  1 
ATOM 1459 C C   . ASN A 1 188 ? 81.005  54.456  85.301  1.00 212.61 ? 188 ASN A C   1 
ATOM 1460 O O   . ASN A 1 188 ? 81.428  55.461  85.883  1.00 212.61 ? 188 ASN A O   1 
ATOM 1461 C CB  . ASN A 1 188 ? 82.843  52.901  84.634  1.00 212.61 ? 188 ASN A CB  1 
ATOM 1462 C CG  . ASN A 1 188 ? 82.425  52.810  83.180  1.00 212.61 ? 188 ASN A CG  1 
ATOM 1463 O OD1 . ASN A 1 188 ? 81.325  52.358  82.865  1.00 212.61 ? 188 ASN A OD1 1 
ATOM 1464 N ND2 . ASN A 1 188 ? 83.308  53.236  82.284  1.00 212.61 ? 188 ASN A ND2 1 
ATOM 1465 N N   . ASN A 1 189 ? 80.001  54.505  84.422  1.00 214.21 ? 189 ASN A N   1 
ATOM 1466 C CA  . ASN A 1 189 ? 79.370  55.779  84.086  1.00 214.21 ? 189 ASN A CA  1 
ATOM 1467 C C   . ASN A 1 189 ? 78.648  56.380  85.286  1.00 214.21 ? 189 ASN A C   1 
ATOM 1468 O O   . ASN A 1 189 ? 78.517  57.606  85.389  1.00 214.21 ? 189 ASN A O   1 
ATOM 1469 C CB  . ASN A 1 189 ? 78.407  55.593  82.914  1.00 214.21 ? 189 ASN A CB  1 
ATOM 1470 C CG  . ASN A 1 189 ? 79.095  55.048  81.680  1.00 214.21 ? 189 ASN A CG  1 
ATOM 1471 O OD1 . ASN A 1 189 ? 79.001  53.859  81.376  1.00 214.21 ? 189 ASN A OD1 1 
ATOM 1472 N ND2 . ASN A 1 189 ? 79.803  55.916  80.967  1.00 214.21 ? 189 ASN A ND2 1 
ATOM 1473 N N   . VAL A 1 190 ? 78.164  55.536  86.199  1.00 215.60 ? 190 VAL A N   1 
ATOM 1474 C CA  . VAL A 1 190 ? 77.548  56.044  87.420  1.00 215.60 ? 190 VAL A CA  1 
ATOM 1475 C C   . VAL A 1 190 ? 78.589  56.737  88.288  1.00 215.60 ? 190 VAL A C   1 
ATOM 1476 O O   . VAL A 1 190 ? 78.296  57.738  88.954  1.00 215.60 ? 190 VAL A O   1 
ATOM 1477 C CB  . VAL A 1 190 ? 76.843  54.904  88.178  1.00 215.60 ? 190 VAL A CB  1 
ATOM 1478 C CG1 . VAL A 1 190 ? 76.115  55.444  89.401  1.00 215.60 ? 190 VAL A CG1 1 
ATOM 1479 C CG2 . VAL A 1 190 ? 75.878  54.171  87.258  1.00 215.60 ? 190 VAL A CG2 1 
ATOM 1480 N N   . LYS A 1 191 ? 79.818  56.217  88.296  1.00 207.63 ? 191 LYS A N   1 
ATOM 1481 C CA  . LYS A 1 191 ? 80.876  56.812  89.106  1.00 207.63 ? 191 LYS A CA  1 
ATOM 1482 C C   . LYS A 1 191 ? 81.228  58.215  88.622  1.00 207.63 ? 191 LYS A C   1 
ATOM 1483 O O   . LYS A 1 191 ? 81.323  59.148  89.428  1.00 207.63 ? 191 LYS A O   1 
ATOM 1484 C CB  . LYS A 1 191 ? 82.114  55.916  89.084  1.00 207.63 ? 191 LYS A CB  1 
ATOM 1485 C CG  . LYS A 1 191 ? 81.822  54.453  89.359  1.00 207.63 ? 191 LYS A CG  1 
ATOM 1486 C CD  . LYS A 1 191 ? 83.050  53.590  89.122  1.00 207.63 ? 191 LYS A CD  1 
ATOM 1487 C CE  . LYS A 1 191 ? 82.727  52.114  89.290  1.00 207.63 ? 191 LYS A CE  1 
ATOM 1488 N NZ  . LYS A 1 191 ? 83.904  51.251  88.995  1.00 207.63 ? 191 LYS A NZ  1 
ATOM 1489 N N   . LEU A 1 192 ? 81.426  58.383  87.312  1.00 207.61 ? 192 LEU A N   1 
ATOM 1490 C CA  . LEU A 1 192 ? 81.791  59.695  86.785  1.00 207.61 ? 192 LEU A CA  1 
ATOM 1491 C C   . LEU A 1 192 ? 80.645  60.687  86.932  1.00 207.61 ? 192 LEU A C   1 
ATOM 1492 O O   . LEU A 1 192 ? 80.875  61.873  87.200  1.00 207.61 ? 192 LEU A O   1 
ATOM 1493 C CB  . LEU A 1 192 ? 82.236  59.578  85.326  1.00 207.61 ? 192 LEU A CB  1 
ATOM 1494 C CG  . LEU A 1 192 ? 81.291  58.995  84.272  1.00 207.61 ? 192 LEU A CG  1 
ATOM 1495 C CD1 . LEU A 1 192 ? 80.475  60.088  83.594  1.00 207.61 ? 192 LEU A CD1 1 
ATOM 1496 C CD2 . LEU A 1 192 ? 82.075  58.193  83.243  1.00 207.61 ? 192 LEU A CD2 1 
ATOM 1497 N N   . ALA A 1 193 ? 79.406  60.227  86.748  1.00 209.77 ? 193 ALA A N   1 
ATOM 1498 C CA  . ALA A 1 193 ? 78.259  61.103  86.961  1.00 209.77 ? 193 ALA A CA  1 
ATOM 1499 C C   . ALA A 1 193 ? 78.185  61.563  88.410  1.00 209.77 ? 193 ALA A C   1 
ATOM 1500 O O   . ALA A 1 193 ? 77.896  62.734  88.683  1.00 209.77 ? 193 ALA A O   1 
ATOM 1501 C CB  . ALA A 1 193 ? 76.970  60.391  86.557  1.00 209.77 ? 193 ALA A CB  1 
ATOM 1502 N N   . ALA A 1 194 ? 78.446  60.656  89.353  1.00 205.67 ? 194 ALA A N   1 
ATOM 1503 C CA  . ALA A 1 194 ? 78.502  61.050  90.756  1.00 205.67 ? 194 ALA A CA  1 
ATOM 1504 C C   . ALA A 1 194 ? 79.656  62.009  91.011  1.00 205.67 ? 194 ALA A C   1 
ATOM 1505 O O   . ALA A 1 194 ? 79.523  62.961  91.790  1.00 205.67 ? 194 ALA A O   1 
ATOM 1506 C CB  . ALA A 1 194 ? 78.623  59.814  91.647  1.00 205.67 ? 194 ALA A CB  1 
ATOM 1507 N N   . THR A 1 195 ? 80.802  61.770  90.368  1.00 186.84 ? 195 THR A N   1 
ATOM 1508 C CA  . THR A 1 195 ? 81.960  62.635  90.568  1.00 186.84 ? 195 THR A CA  1 
ATOM 1509 C C   . THR A 1 195 ? 81.701  64.043  90.045  1.00 186.84 ? 195 THR A C   1 
ATOM 1510 O O   . THR A 1 195 ? 82.049  65.029  90.706  1.00 186.84 ? 195 THR A O   1 
ATOM 1511 C CB  . THR A 1 195 ? 83.189  62.038  89.886  1.00 186.84 ? 195 THR A CB  1 
ATOM 1512 O OG1 . THR A 1 195 ? 83.265  60.636  90.171  1.00 186.84 ? 195 THR A OG1 1 
ATOM 1513 C CG2 . THR A 1 195 ? 84.451  62.718  90.389  1.00 186.84 ? 195 THR A CG2 1 
ATOM 1514 N N   . ASN A 1 196 ? 81.102  64.157  88.857  1.00 188.89 ? 196 ASN A N   1 
ATOM 1515 C CA  . ASN A 1 196 ? 80.819  65.473  88.291  1.00 188.89 ? 196 ASN A CA  1 
ATOM 1516 C C   . ASN A 1 196 ? 79.809  66.236  89.137  1.00 188.89 ? 196 ASN A C   1 
ATOM 1517 O O   . ASN A 1 196 ? 79.962  67.443  89.360  1.00 188.89 ? 196 ASN A O   1 
ATOM 1518 C CB  . ASN A 1 196 ? 80.325  65.331  86.852  1.00 188.89 ? 196 ASN A CB  1 
ATOM 1519 C CG  . ASN A 1 196 ? 81.453  65.049  85.879  1.00 188.89 ? 196 ASN A CG  1 
ATOM 1520 O OD1 . ASN A 1 196 ? 82.578  65.511  86.068  1.00 188.89 ? 196 ASN A OD1 1 
ATOM 1521 N ND2 . ASN A 1 196 ? 81.160  64.284  84.834  1.00 188.89 ? 196 ASN A ND2 1 
ATOM 1522 N N   . ALA A 1 197 ? 78.766  65.554  89.613  1.00 188.58 ? 197 ALA A N   1 
ATOM 1523 C CA  . ALA A 1 197 ? 77.772  66.221  90.445  1.00 188.58 ? 197 ALA A CA  1 
ATOM 1524 C C   . ALA A 1 197 ? 78.357  66.622  91.794  1.00 188.58 ? 197 ALA A C   1 
ATOM 1525 O O   . ALA A 1 197 ? 77.968  67.647  92.365  1.00 188.58 ? 197 ALA A O   1 
ATOM 1526 C CB  . ALA A 1 197 ? 76.554  65.318  90.632  1.00 188.58 ? 197 ALA A CB  1 
ATOM 1527 N N   . LEU A 1 198 ? 79.288  65.822  92.320  1.00 178.77 ? 198 LEU A N   1 
ATOM 1528 C CA  . LEU A 1 198 ? 79.868  66.114  93.627  1.00 178.77 ? 198 LEU A CA  1 
ATOM 1529 C C   . LEU A 1 198 ? 80.659  67.416  93.614  1.00 178.77 ? 198 LEU A C   1 
ATOM 1530 O O   . LEU A 1 198 ? 80.538  68.230  94.537  1.00 178.77 ? 198 LEU A O   1 
ATOM 1531 C CB  . LEU A 1 198 ? 80.754  64.952  94.075  1.00 178.77 ? 198 LEU A CB  1 
ATOM 1532 C CG  . LEU A 1 198 ? 81.413  65.076  95.449  1.00 178.77 ? 198 LEU A CG  1 
ATOM 1533 C CD1 . LEU A 1 198 ? 80.370  65.316  96.525  1.00 178.77 ? 198 LEU A CD1 1 
ATOM 1534 C CD2 . LEU A 1 198 ? 82.225  63.828  95.758  1.00 178.77 ? 198 LEU A CD2 1 
ATOM 1535 N N   . LEU A 1 199 ? 81.473  67.634  92.577  1.00 175.69 ? 199 LEU A N   1 
ATOM 1536 C CA  . LEU A 1 199 ? 82.317  68.824  92.543  1.00 175.69 ? 199 LEU A CA  1 
ATOM 1537 C C   . LEU A 1 199 ? 81.500  70.092  92.331  1.00 175.69 ? 199 LEU A C   1 
ATOM 1538 O O   . LEU A 1 199 ? 81.894  71.167  92.799  1.00 175.69 ? 199 LEU A O   1 
ATOM 1539 C CB  . LEU A 1 199 ? 83.389  68.680  91.457  1.00 175.69 ? 199 LEU A CB  1 
ATOM 1540 C CG  . LEU A 1 199 ? 82.968  68.509  89.994  1.00 175.69 ? 199 LEU A CG  1 
ATOM 1541 C CD1 . LEU A 1 199 ? 82.878  69.850  89.276  1.00 175.69 ? 199 LEU A CD1 1 
ATOM 1542 C CD2 . LEU A 1 199 ? 83.927  67.580  89.268  1.00 175.69 ? 199 LEU A CD2 1 
ATOM 1543 N N   . ASN A 1 200 ? 80.371  69.993  91.628  1.00 184.06 ? 200 ASN A N   1 
ATOM 1544 C CA  . ASN A 1 200 ? 79.518  71.152  91.399  1.00 184.06 ? 200 ASN A CA  1 
ATOM 1545 C C   . ASN A 1 200 ? 78.800  71.622  92.659  1.00 184.06 ? 200 ASN A C   1 
ATOM 1546 O O   . ASN A 1 200 ? 78.295  72.750  92.679  1.00 184.06 ? 200 ASN A O   1 
ATOM 1547 C CB  . ASN A 1 200 ? 78.491  70.843  90.307  1.00 184.06 ? 200 ASN A CB  1 
ATOM 1548 C CG  . ASN A 1 200 ? 79.115  70.760  88.927  1.00 184.06 ? 200 ASN A CG  1 
ATOM 1549 O OD1 . ASN A 1 200 ? 79.224  71.764  88.223  1.00 184.06 ? 200 ASN A OD1 1 
ATOM 1550 N ND2 . ASN A 1 200 ? 79.526  69.561  88.533  1.00 184.06 ? 200 ASN A ND2 1 
ATOM 1551 N N   . SER A 1 201 ? 78.737  70.795  93.701  1.00 196.60 ? 201 SER A N   1 
ATOM 1552 C CA  . SER A 1 201 ? 78.032  71.144  94.927  1.00 196.60 ? 201 SER A CA  1 
ATOM 1553 C C   . SER A 1 201 ? 78.950  71.245  96.138  1.00 196.60 ? 201 SER A C   1 
ATOM 1554 O O   . SER A 1 201 ? 78.537  70.877  97.241  1.00 196.60 ? 201 SER A O   1 
ATOM 1555 C CB  . SER A 1 201 ? 76.925  70.123  95.208  1.00 196.60 ? 201 SER A CB  1 
ATOM 1556 O OG  . SER A 1 201 ? 77.459  68.820  95.361  1.00 196.60 ? 201 SER A OG  1 
ATOM 1557 N N   . LEU A 1 202 ? 80.181  71.731  95.963  1.00 182.41 ? 202 LEU A N   1 
ATOM 1558 C CA  . LEU A 1 202 ? 81.095  71.852  97.093  1.00 182.41 ? 202 LEU A CA  1 
ATOM 1559 C C   . LEU A 1 202 ? 80.964  73.189  97.811  1.00 182.41 ? 202 LEU A C   1 
ATOM 1560 O O   . LEU A 1 202 ? 81.654  73.409  98.813  1.00 182.41 ? 202 LEU A O   1 
ATOM 1561 C CB  . LEU A 1 202 ? 82.538  71.656  96.625  1.00 182.41 ? 202 LEU A CB  1 
ATOM 1562 C CG  . LEU A 1 202 ? 82.881  70.315  95.976  1.00 182.41 ? 202 LEU A CG  1 
ATOM 1563 C CD1 . LEU A 1 202 ? 84.342  70.290  95.556  1.00 182.41 ? 202 LEU A CD1 1 
ATOM 1564 C CD2 . LEU A 1 202 ? 82.573  69.161  96.916  1.00 182.41 ? 202 LEU A CD2 1 
ATOM 1565 N N   . GLU A 1 203 ? 80.103  74.086  97.328  1.00 207.78 ? 203 GLU A N   1 
ATOM 1566 C CA  . GLU A 1 203 ? 80.010  75.424  97.899  1.00 207.78 ? 203 GLU A CA  1 
ATOM 1567 C C   . GLU A 1 203 ? 79.013  75.528  99.047  1.00 207.78 ? 203 GLU A C   1 
ATOM 1568 O O   . GLU A 1 203 ? 79.000  76.554  99.736  1.00 207.78 ? 203 GLU A O   1 
ATOM 1569 C CB  . GLU A 1 203 ? 79.645  76.443  96.812  1.00 207.78 ? 203 GLU A CB  1 
ATOM 1570 C CG  . GLU A 1 203 ? 78.292  76.222  96.148  1.00 207.78 ? 203 GLU A CG  1 
ATOM 1571 C CD  . GLU A 1 203 ? 78.332  75.174  95.050  1.00 207.78 ? 203 GLU A CD  1 
ATOM 1572 O OE1 . GLU A 1 203 ? 79.419  74.610  94.798  1.00 207.78 ? 203 GLU A OE1 1 
ATOM 1573 O OE2 . GLU A 1 203 ? 77.275  74.917  94.435  1.00 207.78 ? 203 GLU A OE2 1 
ATOM 1574 N N   . PHE A 1 204 ? 78.191  74.508  99.277  1.00 200.72 ? 204 PHE A N   1 
ATOM 1575 C CA  . PHE A 1 204 ? 77.223  74.518  100.369 1.00 200.72 ? 204 PHE A CA  1 
ATOM 1576 C C   . PHE A 1 204 ? 77.246  73.199  101.127 1.00 200.72 ? 204 PHE A C   1 
ATOM 1577 O O   . PHE A 1 204 ? 76.297  72.849  101.834 1.00 200.72 ? 204 PHE A O   1 
ATOM 1578 C CB  . PHE A 1 204 ? 75.816  74.830  99.862  1.00 200.72 ? 204 PHE A CB  1 
ATOM 1579 C CG  . PHE A 1 204 ? 75.404  74.033  98.658  1.00 200.72 ? 204 PHE A CG  1 
ATOM 1580 C CD1 . PHE A 1 204 ? 75.010  72.712  98.781  1.00 200.72 ? 204 PHE A CD1 1 
ATOM 1581 C CD2 . PHE A 1 204 ? 75.385  74.618  97.403  1.00 200.72 ? 204 PHE A CD2 1 
ATOM 1582 C CE1 . PHE A 1 204 ? 74.623  71.985  97.674  1.00 200.72 ? 204 PHE A CE1 1 
ATOM 1583 C CE2 . PHE A 1 204 ? 74.998  73.895  96.293  1.00 200.72 ? 204 PHE A CE2 1 
ATOM 1584 C CZ  . PHE A 1 204 ? 74.617  72.578  96.429  1.00 200.72 ? 204 PHE A CZ  1 
ATOM 1585 N N   . THR A 1 205 ? 78.334  72.446  100.991 1.00 193.08 ? 205 THR A N   1 
ATOM 1586 C CA  . THR A 1 205 ? 78.511  71.206  101.733 1.00 193.08 ? 205 THR A CA  1 
ATOM 1587 C C   . THR A 1 205 ? 79.132  71.425  103.107 1.00 193.08 ? 205 THR A C   1 
ATOM 1588 O O   . THR A 1 205 ? 79.408  70.446  103.808 1.00 193.08 ? 205 THR A O   1 
ATOM 1589 C CB  . THR A 1 205 ? 79.369  70.221  100.932 1.00 193.08 ? 205 THR A CB  1 
ATOM 1590 O OG1 . THR A 1 205 ? 79.594  69.040  101.710 1.00 193.08 ? 205 THR A OG1 1 
ATOM 1591 C CG2 . THR A 1 205 ? 80.706  70.846  100.573 1.00 193.08 ? 205 THR A CG2 1 
ATOM 1592 N N   . LYS A 1 206 ? 79.371  72.679  103.499 1.00 195.08 ? 206 LYS A N   1 
ATOM 1593 C CA  . LYS A 1 206 ? 79.943  72.963  104.810 1.00 195.08 ? 206 LYS A CA  1 
ATOM 1594 C C   . LYS A 1 206 ? 79.042  72.504  105.950 1.00 195.08 ? 206 LYS A C   1 
ATOM 1595 O O   . LYS A 1 206 ? 79.546  72.212  107.040 1.00 195.08 ? 206 LYS A O   1 
ATOM 1596 C CB  . LYS A 1 206 ? 80.241  74.457  104.942 1.00 195.08 ? 206 LYS A CB  1 
ATOM 1597 C CG  . LYS A 1 206 ? 79.033  75.358  104.748 1.00 195.08 ? 206 LYS A CG  1 
ATOM 1598 C CD  . LYS A 1 206 ? 79.445  76.817  104.642 1.00 195.08 ? 206 LYS A CD  1 
ATOM 1599 C CE  . LYS A 1 206 ? 80.329  77.053  103.428 1.00 195.08 ? 206 LYS A CE  1 
ATOM 1600 N NZ  . LYS A 1 206 ? 79.635  76.695  102.159 1.00 195.08 ? 206 LYS A NZ  1 
ATOM 1601 N N   . ALA A 1 207 ? 77.725  72.439  105.728 1.00 211.02 ? 207 ALA A N   1 
ATOM 1602 C CA  . ALA A 1 207 ? 76.832  71.894  106.745 1.00 211.02 ? 207 ALA A CA  1 
ATOM 1603 C C   . ALA A 1 207 ? 77.134  70.428  107.023 1.00 211.02 ? 207 ALA A C   1 
ATOM 1604 O O   . ALA A 1 207 ? 76.883  69.943  108.132 1.00 211.02 ? 207 ALA A O   1 
ATOM 1605 C CB  . ALA A 1 207 ? 75.375  72.065  106.315 1.00 211.02 ? 207 ALA A CB  1 
ATOM 1606 N N   . ASN A 1 208 ? 77.660  69.710  106.032 1.00 212.00 ? 208 ASN A N   1 
ATOM 1607 C CA  . ASN A 1 208 ? 78.113  68.341  106.212 1.00 212.00 ? 208 ASN A CA  1 
ATOM 1608 C C   . ASN A 1 208 ? 79.592  68.248  106.551 1.00 212.00 ? 208 ASN A C   1 
ATOM 1609 O O   . ASN A 1 208 ? 80.038  67.198  107.028 1.00 212.00 ? 208 ASN A O   1 
ATOM 1610 C CB  . ASN A 1 208 ? 77.834  67.523  104.943 1.00 212.00 ? 208 ASN A CB  1 
ATOM 1611 C CG  . ASN A 1 208 ? 76.486  67.842  104.332 1.00 212.00 ? 208 ASN A CG  1 
ATOM 1612 O OD1 . ASN A 1 208 ? 76.354  68.784  103.550 1.00 212.00 ? 208 ASN A OD1 1 
ATOM 1613 N ND2 . ASN A 1 208 ? 75.475  67.059  104.687 1.00 212.00 ? 208 ASN A ND2 1 
ATOM 1614 N N   . PHE A 1 209 ? 80.359  69.314  106.314 1.00 203.15 ? 209 PHE A N   1 
ATOM 1615 C CA  . PHE A 1 209 ? 81.794  69.309  106.565 1.00 203.15 ? 209 PHE A CA  1 
ATOM 1616 C C   . PHE A 1 209 ? 82.133  69.284  108.050 1.00 203.15 ? 209 PHE A C   1 
ATOM 1617 O O   . PHE A 1 209 ? 83.169  68.725  108.424 1.00 203.15 ? 209 PHE A O   1 
ATOM 1618 C CB  . PHE A 1 209 ? 82.430  70.532  105.900 1.00 203.15 ? 209 PHE A CB  1 
ATOM 1619 C CG  . PHE A 1 209 ? 83.896  70.695  106.187 1.00 203.15 ? 209 PHE A CG  1 
ATOM 1620 C CD1 . PHE A 1 209 ? 84.840  69.989  105.462 1.00 203.15 ? 209 PHE A CD1 1 
ATOM 1621 C CD2 . PHE A 1 209 ? 84.330  71.573  107.168 1.00 203.15 ? 209 PHE A CD2 1 
ATOM 1622 C CE1 . PHE A 1 209 ? 86.189  70.145  105.719 1.00 203.15 ? 209 PHE A CE1 1 
ATOM 1623 C CE2 . PHE A 1 209 ? 85.677  71.731  107.429 1.00 203.15 ? 209 PHE A CE2 1 
ATOM 1624 C CZ  . PHE A 1 209 ? 86.607  71.016  106.704 1.00 203.15 ? 209 PHE A CZ  1 
ATOM 1625 N N   . ASP A 1 210 ? 81.292  69.880  108.901 1.00 215.55 ? 210 ASP A N   1 
ATOM 1626 C CA  . ASP A 1 210 ? 81.611  69.985  110.321 1.00 215.55 ? 210 ASP A CA  1 
ATOM 1627 C C   . ASP A 1 210 ? 81.694  68.630  111.013 1.00 215.55 ? 210 ASP A C   1 
ATOM 1628 O O   . ASP A 1 210 ? 82.414  68.504  112.009 1.00 215.55 ? 210 ASP A O   1 
ATOM 1629 C CB  . ASP A 1 210 ? 80.582  70.871  111.027 1.00 215.55 ? 210 ASP A CB  1 
ATOM 1630 C CG  . ASP A 1 210 ? 79.154  70.456  110.733 1.00 215.55 ? 210 ASP A CG  1 
ATOM 1631 O OD1 . ASP A 1 210 ? 78.747  69.360  111.171 1.00 215.55 ? 210 ASP A OD1 1 
ATOM 1632 O OD2 . ASP A 1 210 ? 78.437  71.232  110.067 1.00 215.55 ? 210 ASP A OD2 1 
ATOM 1633 N N   . LYS A 1 211 ? 80.984  67.620  110.516 1.00 210.78 ? 211 LYS A N   1 
ATOM 1634 C CA  . LYS A 1 211 ? 81.011  66.303  111.136 1.00 210.78 ? 211 LYS A CA  1 
ATOM 1635 C C   . LYS A 1 211 ? 82.244  65.535  110.676 1.00 210.78 ? 211 LYS A C   1 
ATOM 1636 O O   . LYS A 1 211 ? 82.371  65.197  109.494 1.00 210.78 ? 211 LYS A O   1 
ATOM 1637 C CB  . LYS A 1 211 ? 79.743  65.521  110.799 1.00 210.78 ? 211 LYS A CB  1 
ATOM 1638 C CG  . LYS A 1 211 ? 79.607  64.221  111.576 1.00 210.78 ? 211 LYS A CG  1 
ATOM 1639 C CD  . LYS A 1 211 ? 79.418  64.491  113.061 1.00 210.78 ? 211 LYS A CD  1 
ATOM 1640 C CE  . LYS A 1 211 ? 79.805  63.282  113.896 1.00 210.78 ? 211 LYS A CE  1 
ATOM 1641 N NZ  . LYS A 1 211 ? 81.271  63.031  113.840 1.00 210.78 ? 211 LYS A NZ  1 
ATOM 1642 N N   . GLU A 1 212 ? 83.154  65.264  111.615 1.00 211.16 ? 212 GLU A N   1 
ATOM 1643 C CA  . GLU A 1 212 ? 84.396  64.576  111.276 1.00 211.16 ? 212 GLU A CA  1 
ATOM 1644 C C   . GLU A 1 212 ? 84.133  63.167  110.757 1.00 211.16 ? 212 GLU A C   1 
ATOM 1645 O O   . GLU A 1 212 ? 84.780  62.723  109.801 1.00 211.16 ? 212 GLU A O   1 
ATOM 1646 C CB  . GLU A 1 212 ? 85.324  64.535  112.491 1.00 211.16 ? 212 GLU A CB  1 
ATOM 1647 C CG  . GLU A 1 212 ? 86.033  65.849  112.789 1.00 211.16 ? 212 GLU A CG  1 
ATOM 1648 C CD  . GLU A 1 212 ? 85.100  66.924  113.315 1.00 211.16 ? 212 GLU A CD  1 
ATOM 1649 O OE1 . GLU A 1 212 ? 84.004  66.578  113.803 1.00 211.16 ? 212 GLU A OE1 1 
ATOM 1650 O OE2 . GLU A 1 212 ? 85.465  68.116  113.241 1.00 211.16 ? 212 GLU A OE2 1 
ATOM 1651 N N   . SER A 1 213 ? 83.197  62.446  111.380 1.00 212.12 ? 213 SER A N   1 
ATOM 1652 C CA  . SER A 1 213 ? 82.871  61.102  110.911 1.00 212.12 ? 213 SER A CA  1 
ATOM 1653 C C   . SER A 1 213 ? 82.333  61.134  109.486 1.00 212.12 ? 213 SER A C   1 
ATOM 1654 O O   . SER A 1 213 ? 82.711  60.300  108.654 1.00 212.12 ? 213 SER A O   1 
ATOM 1655 C CB  . SER A 1 213 ? 81.862  60.446  111.853 1.00 212.12 ? 213 SER A CB  1 
ATOM 1656 O OG  . SER A 1 213 ? 81.534  59.138  111.420 1.00 212.12 ? 213 SER A OG  1 
ATOM 1657 N N   . GLU A 1 214 ? 81.446  62.085  109.189 1.00 210.26 ? 214 GLU A N   1 
ATOM 1658 C CA  . GLU A 1 214 ? 80.962  62.249  107.822 1.00 210.26 ? 214 GLU A CA  1 
ATOM 1659 C C   . GLU A 1 214 ? 82.073  62.734  106.900 1.00 210.26 ? 214 GLU A C   1 
ATOM 1660 O O   . GLU A 1 214 ? 82.163  62.301  105.745 1.00 210.26 ? 214 GLU A O   1 
ATOM 1661 C CB  . GLU A 1 214 ? 79.781  63.217  107.801 1.00 210.26 ? 214 GLU A CB  1 
ATOM 1662 C CG  . GLU A 1 214 ? 79.120  63.368  106.444 1.00 210.26 ? 214 GLU A CG  1 
ATOM 1663 C CD  . GLU A 1 214 ? 77.962  64.343  106.473 1.00 210.26 ? 214 GLU A CD  1 
ATOM 1664 O OE1 . GLU A 1 214 ? 77.828  65.076  107.475 1.00 210.26 ? 214 GLU A OE1 1 
ATOM 1665 O OE2 . GLU A 1 214 ? 77.183  64.375  105.498 1.00 210.26 ? 214 GLU A OE2 1 
ATOM 1666 N N   . ARG A 1 215 ? 82.924  63.639  107.391 1.00 199.13 ? 215 ARG A N   1 
ATOM 1667 C CA  . ARG A 1 215 ? 84.039  64.129  106.586 1.00 199.13 ? 215 ARG A CA  1 
ATOM 1668 C C   . ARG A 1 215 ? 84.991  62.998  106.221 1.00 199.13 ? 215 ARG A C   1 
ATOM 1669 O O   . ARG A 1 215 ? 85.459  62.914  105.079 1.00 199.13 ? 215 ARG A O   1 
ATOM 1670 C CB  . ARG A 1 215 ? 84.777  65.235  107.339 1.00 199.13 ? 215 ARG A CB  1 
ATOM 1671 C CG  . ARG A 1 215 ? 85.948  65.839  106.583 1.00 199.13 ? 215 ARG A CG  1 
ATOM 1672 C CD  . ARG A 1 215 ? 86.482  67.069  107.299 1.00 199.13 ? 215 ARG A CD  1 
ATOM 1673 N NE  . ARG A 1 215 ? 87.132  66.744  108.563 1.00 199.13 ? 215 ARG A NE  1 
ATOM 1674 C CZ  . ARG A 1 215 ? 87.448  67.636  109.492 1.00 199.13 ? 215 ARG A CZ  1 
ATOM 1675 N NH1 . ARG A 1 215 ? 87.157  68.918  109.345 1.00 199.13 ? 215 ARG A NH1 1 
ATOM 1676 N NH2 . ARG A 1 215 ? 88.070  67.232  110.596 1.00 199.13 ? 215 ARG A NH2 1 
ATOM 1677 N N   . HIS A 1 216 ? 85.288  62.118  107.179 1.00 204.19 ? 216 HIS A N   1 
ATOM 1678 C CA  . HIS A 1 216 ? 86.109  60.949  106.882 1.00 204.19 ? 216 HIS A CA  1 
ATOM 1679 C C   . HIS A 1 216 ? 85.397  60.016  105.911 1.00 204.19 ? 216 HIS A C   1 
ATOM 1680 O O   . HIS A 1 216 ? 86.037  59.381  105.064 1.00 204.19 ? 216 HIS A O   1 
ATOM 1681 C CB  . HIS A 1 216 ? 86.455  60.217  108.179 1.00 204.19 ? 216 HIS A CB  1 
ATOM 1682 C CG  . HIS A 1 216 ? 87.314  59.008  107.983 1.00 204.19 ? 216 HIS A CG  1 
ATOM 1683 N ND1 . HIS A 1 216 ? 88.660  59.089  107.695 1.00 204.19 ? 216 HIS A ND1 1 
ATOM 1684 C CD2 . HIS A 1 216 ? 87.021  57.687  108.040 1.00 204.19 ? 216 HIS A CD2 1 
ATOM 1685 C CE1 . HIS A 1 216 ? 89.158  57.871  107.581 1.00 204.19 ? 216 HIS A CE1 1 
ATOM 1686 N NE2 . HIS A 1 216 ? 88.184  57.002  107.785 1.00 204.19 ? 216 HIS A NE2 1 
ATOM 1687 N N   . PHE A 1 217 ? 84.070  59.921  106.021 1.00 202.70 ? 217 PHE A N   1 
ATOM 1688 C CA  . PHE A 1 217 ? 83.298  59.071  105.120 1.00 202.70 ? 217 PHE A CA  1 
ATOM 1689 C C   . PHE A 1 217 ? 83.383  59.567  103.681 1.00 202.70 ? 217 PHE A C   1 
ATOM 1690 O O   . PHE A 1 217 ? 83.560  58.771  102.751 1.00 202.70 ? 217 PHE A O   1 
ATOM 1691 C CB  . PHE A 1 217 ? 81.843  59.019  105.588 1.00 202.70 ? 217 PHE A CB  1 
ATOM 1692 C CG  . PHE A 1 217 ? 80.989  58.034  104.837 1.00 202.70 ? 217 PHE A CG  1 
ATOM 1693 C CD1 . PHE A 1 217 ? 81.540  56.896  104.271 1.00 202.70 ? 217 PHE A CD1 1 
ATOM 1694 C CD2 . PHE A 1 217 ? 79.627  58.251  104.700 1.00 202.70 ? 217 PHE A CD2 1 
ATOM 1695 C CE1 . PHE A 1 217 ? 80.748  55.995  103.583 1.00 202.70 ? 217 PHE A CE1 1 
ATOM 1696 C CE2 . PHE A 1 217 ? 78.832  57.355  104.013 1.00 202.70 ? 217 PHE A CE2 1 
ATOM 1697 C CZ  . PHE A 1 217 ? 79.393  56.225  103.454 1.00 202.70 ? 217 PHE A CZ  1 
ATOM 1698 N N   . ILE A 1 218 ? 83.253  60.879  103.479 1.00 198.55 ? 218 ILE A N   1 
ATOM 1699 C CA  . ILE A 1 218 ? 83.271  61.434  102.128 1.00 198.55 ? 218 ILE A CA  1 
ATOM 1700 C C   . ILE A 1 218 ? 84.649  61.275  101.498 1.00 198.55 ? 218 ILE A C   1 
ATOM 1701 O O   . ILE A 1 218 ? 84.772  60.853  100.341 1.00 198.55 ? 218 ILE A O   1 
ATOM 1702 C CB  . ILE A 1 218 ? 82.824  62.907  102.157 1.00 198.55 ? 218 ILE A CB  1 
ATOM 1703 C CG1 . ILE A 1 218 ? 81.371  63.009  102.624 1.00 198.55 ? 218 ILE A CG1 1 
ATOM 1704 C CG2 . ILE A 1 218 ? 82.992  63.547  100.789 1.00 198.55 ? 218 ILE A CG2 1 
ATOM 1705 C CD1 . ILE A 1 218 ? 80.894  64.428  102.816 1.00 198.55 ? 218 ILE A CD1 1 
ATOM 1706 N N   . MET A 1 219 ? 85.707  61.609  102.242 1.00 195.64 ? 219 MET A N   1 
ATOM 1707 C CA  . MET A 1 219 ? 87.058  61.471  101.709 1.00 195.64 ? 219 MET A CA  1 
ATOM 1708 C C   . MET A 1 219 ? 87.450  60.010  101.531 1.00 195.64 ? 219 MET A C   1 
ATOM 1709 O O   . MET A 1 219 ? 88.339  59.703  100.729 1.00 195.64 ? 219 MET A O   1 
ATOM 1710 C CB  . MET A 1 219 ? 88.057  62.181  102.618 1.00 195.64 ? 219 MET A CB  1 
ATOM 1711 C CG  . MET A 1 219 ? 87.789  63.664  102.782 1.00 195.64 ? 219 MET A CG  1 
ATOM 1712 S SD  . MET A 1 219 ? 88.897  64.408  103.988 1.00 195.64 ? 219 MET A SD  1 
ATOM 1713 C CE  . MET A 1 219 ? 88.726  63.237  105.332 1.00 195.64 ? 219 MET A CE  1 
ATOM 1714 N N   . GLN A 1 220 ? 86.816  59.102  102.277 1.00 197.89 ? 220 GLN A N   1 
ATOM 1715 C CA  . GLN A 1 220 ? 87.066  57.678  102.079 1.00 197.89 ? 220 GLN A CA  1 
ATOM 1716 C C   . GLN A 1 220 ? 86.674  57.246  100.671 1.00 197.89 ? 220 GLN A C   1 
ATOM 1717 O O   . GLN A 1 220 ? 87.257  56.308  100.115 1.00 197.89 ? 220 GLN A O   1 
ATOM 1718 C CB  . GLN A 1 220 ? 86.304  56.863  103.124 1.00 197.89 ? 220 GLN A CB  1 
ATOM 1719 C CG  . GLN A 1 220 ? 86.658  55.384  103.158 1.00 197.89 ? 220 GLN A CG  1 
ATOM 1720 C CD  . GLN A 1 220 ? 87.996  55.117  103.820 1.00 197.89 ? 220 GLN A CD  1 
ATOM 1721 O OE1 . GLN A 1 220 ? 88.592  54.056  103.633 1.00 197.89 ? 220 GLN A OE1 1 
ATOM 1722 N NE2 . GLN A 1 220 ? 88.472  56.076  104.606 1.00 197.89 ? 220 GLN A NE2 1 
ATOM 1723 N N   . VAL A 1 221 ? 85.689  57.924  100.080 1.00 198.63 ? 221 VAL A N   1 
ATOM 1724 C CA  . VAL A 1 221 ? 85.246  57.578  98.733  1.00 198.63 ? 221 VAL A CA  1 
ATOM 1725 C C   . VAL A 1 221 ? 86.248  58.066  97.694  1.00 198.63 ? 221 VAL A C   1 
ATOM 1726 O O   . VAL A 1 221 ? 86.718  57.289  96.854  1.00 198.63 ? 221 VAL A O   1 
ATOM 1727 C CB  . VAL A 1 221 ? 83.841  58.151  98.472  1.00 198.63 ? 221 VAL A CB  1 
ATOM 1728 C CG1 . VAL A 1 221 ? 83.383  57.805  97.068  1.00 198.63 ? 221 VAL A CG1 1 
ATOM 1729 C CG2 . VAL A 1 221 ? 82.857  57.630  99.507  1.00 198.63 ? 221 VAL A CG2 1 
ATOM 1730 N N   . VAL A 1 222 ? 86.595  59.355  97.737  1.00 198.65 ? 222 VAL A N   1 
ATOM 1731 C CA  . VAL A 1 222 ? 87.434  59.933  96.690  1.00 198.65 ? 222 VAL A CA  1 
ATOM 1732 C C   . VAL A 1 222 ? 88.821  59.299  96.673  1.00 198.65 ? 222 VAL A C   1 
ATOM 1733 O O   . VAL A 1 222 ? 89.381  59.068  95.596  1.00 198.65 ? 222 VAL A O   1 
ATOM 1734 C CB  . VAL A 1 222 ? 87.513  61.464  96.838  1.00 198.65 ? 222 VAL A CB  1 
ATOM 1735 C CG1 . VAL A 1 222 ? 86.154  62.092  96.567  1.00 198.65 ? 222 VAL A CG1 1 
ATOM 1736 C CG2 . VAL A 1 222 ? 88.012  61.854  98.218  1.00 198.65 ? 222 VAL A CG2 1 
ATOM 1737 N N   . CYS A 1 223 ? 89.395  59.002  97.841  1.00 203.34 ? 223 CYS A N   1 
ATOM 1738 C CA  . CYS A 1 223 ? 90.686  58.324  97.871  1.00 203.34 ? 223 CYS A CA  1 
ATOM 1739 C C   . CYS A 1 223 ? 90.602  56.953  97.212  1.00 203.34 ? 223 CYS A C   1 
ATOM 1740 O O   . CYS A 1 223 ? 91.513  56.553  96.479  1.00 203.34 ? 223 CYS A O   1 
ATOM 1741 C CB  . CYS A 1 223 ? 91.183  58.200  99.312  1.00 203.34 ? 223 CYS A CB  1 
ATOM 1742 S SG  . CYS A 1 223 ? 91.544  59.778  100.118 1.00 203.34 ? 223 CYS A SG  1 
ATOM 1743 N N   . GLU A 1 224 ? 89.516  56.219  97.464  1.00 203.94 ? 224 GLU A N   1 
ATOM 1744 C CA  . GLU A 1 224 ? 89.315  54.938  96.797  1.00 203.94 ? 224 GLU A CA  1 
ATOM 1745 C C   . GLU A 1 224 ? 88.841  55.117  95.358  1.00 203.94 ? 224 GLU A C   1 
ATOM 1746 O O   . GLU A 1 224 ? 89.130  54.271  94.504  1.00 203.94 ? 224 GLU A O   1 
ATOM 1747 C CB  . GLU A 1 224 ? 88.323  54.088  97.591  1.00 203.94 ? 224 GLU A CB  1 
ATOM 1748 C CG  . GLU A 1 224 ? 88.834  53.679  98.966  1.00 203.94 ? 224 GLU A CG  1 
ATOM 1749 C CD  . GLU A 1 224 ? 87.730  53.188  99.882  1.00 203.94 ? 224 GLU A CD  1 
ATOM 1750 O OE1 . GLU A 1 224 ? 86.544  53.399  99.552  1.00 203.94 ? 224 GLU A OE1 1 
ATOM 1751 O OE2 . GLU A 1 224 ? 88.050  52.595  100.934 1.00 203.94 ? 224 GLU A OE2 1 
ATOM 1752 N N   . ALA A 1 225 ? 88.115  56.201  95.070  1.00 198.76 ? 225 ALA A N   1 
ATOM 1753 C CA  . ALA A 1 225 ? 87.660  56.457  93.707  1.00 198.76 ? 225 ALA A CA  1 
ATOM 1754 C C   . ALA A 1 225 ? 88.800  56.881  92.790  1.00 198.76 ? 225 ALA A C   1 
ATOM 1755 O O   . ALA A 1 225 ? 88.724  56.661  91.577  1.00 198.76 ? 225 ALA A O   1 
ATOM 1756 C CB  . ALA A 1 225 ? 86.563  57.524  93.704  1.00 198.76 ? 225 ALA A CB  1 
ATOM 1757 N N   . THR A 1 226 ? 89.848  57.499  93.342  1.00 190.35 ? 226 THR A N   1 
ATOM 1758 C CA  . THR A 1 226 ? 90.999  57.888  92.535  1.00 190.35 ? 226 THR A CA  1 
ATOM 1759 C C   . THR A 1 226 ? 91.695  56.692  91.900  1.00 190.35 ? 226 THR A C   1 
ATOM 1760 O O   . THR A 1 226 ? 92.270  56.833  90.817  1.00 190.35 ? 226 THR A O   1 
ATOM 1761 C CB  . THR A 1 226 ? 92.009  58.674  93.373  1.00 190.35 ? 226 THR A CB  1 
ATOM 1762 O OG1 . THR A 1 226 ? 92.221  58.008  94.625  1.00 190.35 ? 226 THR A OG1 1 
ATOM 1763 C CG2 . THR A 1 226 ? 91.520  60.095  93.620  1.00 190.35 ? 226 THR A CG2 1 
ATOM 1764 N N   . GLN A 1 227 ? 91.671  55.529  92.550  1.00 180.43 ? 227 GLN A N   1 
ATOM 1765 C CA  . GLN A 1 227 ? 92.336  54.333  92.050  1.00 180.43 ? 227 GLN A CA  1 
ATOM 1766 C C   . GLN A 1 227 ? 91.512  53.598  90.996  1.00 180.43 ? 227 GLN A C   1 
ATOM 1767 O O   . GLN A 1 227 ? 91.856  52.470  90.627  1.00 180.43 ? 227 GLN A O   1 
ATOM 1768 C CB  . GLN A 1 227 ? 92.669  53.394  93.210  1.00 180.43 ? 227 GLN A CB  1 
ATOM 1769 C CG  . GLN A 1 227 ? 93.342  54.077  94.395  1.00 180.43 ? 227 GLN A CG  1 
ATOM 1770 C CD  . GLN A 1 227 ? 94.754  54.544  94.089  1.00 180.43 ? 227 GLN A CD  1 
ATOM 1771 O OE1 . GLN A 1 227 ? 95.349  54.154  93.085  1.00 180.43 ? 227 GLN A OE1 1 
ATOM 1772 N NE2 . GLN A 1 227 ? 95.300  55.383  94.963  1.00 180.43 ? 227 GLN A NE2 1 
ATOM 1773 N N   . CYS A 1 228 ? 90.430  54.205  90.516  1.00 176.81 ? 228 CYS A N   1 
ATOM 1774 C CA  . CYS A 1 228 ? 89.594  53.562  89.511  1.00 176.81 ? 228 CYS A CA  1 
ATOM 1775 C C   . CYS A 1 228 ? 90.378  53.370  88.213  1.00 176.81 ? 228 CYS A C   1 
ATOM 1776 O O   . CYS A 1 228 ? 91.112  54.269  87.792  1.00 176.81 ? 228 CYS A O   1 
ATOM 1777 C CB  . CYS A 1 228 ? 88.341  54.398  89.251  1.00 176.81 ? 228 CYS A CB  1 
ATOM 1778 S SG  . CYS A 1 228 ? 87.165  53.687  88.077  1.00 176.81 ? 228 CYS A SG  1 
ATOM 1779 N N   . PRO A 1 229 ? 90.254  52.208  87.563  1.00 183.66 ? 229 PRO A N   1 
ATOM 1780 C CA  . PRO A 1 229 ? 90.999  51.992  86.311  1.00 183.66 ? 229 PRO A CA  1 
ATOM 1781 C C   . PRO A 1 229 ? 90.635  52.968  85.205  1.00 183.66 ? 229 PRO A C   1 
ATOM 1782 O O   . PRO A 1 229 ? 91.483  53.257  84.351  1.00 183.66 ? 229 PRO A O   1 
ATOM 1783 C CB  . PRO A 1 229 ? 90.637  50.549  85.930  1.00 183.66 ? 229 PRO A CB  1 
ATOM 1784 C CG  . PRO A 1 229 ? 89.343  50.285  86.631  1.00 183.66 ? 229 PRO A CG  1 
ATOM 1785 C CD  . PRO A 1 229 ? 89.437  51.037  87.925  1.00 183.66 ? 229 PRO A CD  1 
ATOM 1786 N N   . ASP A 1 230 ? 89.405  53.475  85.184  1.00 182.79 ? 230 ASP A N   1 
ATOM 1787 C CA  . ASP A 1 230 ? 88.975  54.385  84.131  1.00 182.79 ? 230 ASP A CA  1 
ATOM 1788 C C   . ASP A 1 230 ? 89.704  55.717  84.262  1.00 182.79 ? 230 ASP A C   1 
ATOM 1789 O O   . ASP A 1 230 ? 89.717  56.324  85.337  1.00 182.79 ? 230 ASP A O   1 
ATOM 1790 C CB  . ASP A 1 230 ? 87.463  54.594  84.198  1.00 182.79 ? 230 ASP A CB  1 
ATOM 1791 C CG  . ASP A 1 230 ? 86.884  55.118  82.895  1.00 182.79 ? 230 ASP A CG  1 
ATOM 1792 O OD1 . ASP A 1 230 ? 87.586  55.861  82.178  1.00 182.79 ? 230 ASP A OD1 1 
ATOM 1793 O OD2 . ASP A 1 230 ? 85.721  54.781  82.587  1.00 182.79 ? 230 ASP A OD2 1 
ATOM 1794 N N   . THR A 1 231 ? 90.301  56.173  83.157  1.00 168.08 ? 231 THR A N   1 
ATOM 1795 C CA  . THR A 1 231 ? 91.070  57.414  83.179  1.00 168.08 ? 231 THR A CA  1 
ATOM 1796 C C   . THR A 1 231 ? 90.194  58.622  83.486  1.00 168.08 ? 231 THR A C   1 
ATOM 1797 O O   . THR A 1 231 ? 90.644  59.553  84.163  1.00 168.08 ? 231 THR A O   1 
ATOM 1798 C CB  . THR A 1 231 ? 91.797  57.607  81.845  1.00 168.08 ? 231 THR A CB  1 
ATOM 1799 O OG1 . THR A 1 231 ? 92.358  58.925  81.788  1.00 168.08 ? 231 THR A OG1 1 
ATOM 1800 C CG2 . THR A 1 231 ? 90.843  57.408  80.674  1.00 168.08 ? 231 THR A CG2 1 
ATOM 1801 N N   . ARG A 1 232 ? 88.955  58.633  82.989  1.00 162.92 ? 232 ARG A N   1 
ATOM 1802 C CA  . ARG A 1 232 ? 88.056  59.749  83.262  1.00 162.92 ? 232 ARG A CA  1 
ATOM 1803 C C   . ARG A 1 232 ? 87.758  59.869  84.751  1.00 162.92 ? 232 ARG A C   1 
ATOM 1804 O O   . ARG A 1 232 ? 87.702  60.980  85.290  1.00 162.92 ? 232 ARG A O   1 
ATOM 1805 C CB  . ARG A 1 232 ? 86.764  59.587  82.463  1.00 162.92 ? 232 ARG A CB  1 
ATOM 1806 C CG  . ARG A 1 232 ? 86.934  59.821  80.971  1.00 162.92 ? 232 ARG A CG  1 
ATOM 1807 C CD  . ARG A 1 232 ? 85.727  59.328  80.192  1.00 162.92 ? 232 ARG A CD  1 
ATOM 1808 N NE  . ARG A 1 232 ? 85.559  57.885  80.318  1.00 162.92 ? 232 ARG A NE  1 
ATOM 1809 C CZ  . ARG A 1 232 ? 84.633  57.178  79.684  1.00 162.92 ? 232 ARG A CZ  1 
ATOM 1810 N NH1 . ARG A 1 232 ? 83.767  57.750  78.864  1.00 162.92 ? 232 ARG A NH1 1 
ATOM 1811 N NH2 . ARG A 1 232 ? 84.575  55.864  79.878  1.00 162.92 ? 232 ARG A NH2 1 
ATOM 1812 N N   . VAL A 1 233 ? 87.562  58.739  85.432  1.00 160.37 ? 233 VAL A N   1 
ATOM 1813 C CA  . VAL A 1 233 ? 87.342  58.779  86.874  1.00 160.37 ? 233 VAL A CA  1 
ATOM 1814 C C   . VAL A 1 233 ? 88.600  59.251  87.593  1.00 160.37 ? 233 VAL A C   1 
ATOM 1815 O O   . VAL A 1 233 ? 88.515  59.938  88.618  1.00 160.37 ? 233 VAL A O   1 
ATOM 1816 C CB  . VAL A 1 233 ? 86.876  57.404  87.388  1.00 160.37 ? 233 VAL A CB  1 
ATOM 1817 C CG1 . VAL A 1 233 ? 86.465  57.492  88.852  1.00 160.37 ? 233 VAL A CG1 1 
ATOM 1818 C CG2 . VAL A 1 233 ? 85.726  56.883  86.542  1.00 160.37 ? 233 VAL A CG2 1 
ATOM 1819 N N   . ARG A 1 234 ? 89.779  58.894  87.077  1.00 160.32 ? 234 ARG A N   1 
ATOM 1820 C CA  . ARG A 1 234 ? 91.030  59.329  87.695  1.00 160.32 ? 234 ARG A CA  1 
ATOM 1821 C C   . ARG A 1 234 ? 91.123  60.849  87.743  1.00 160.32 ? 234 ARG A C   1 
ATOM 1822 O O   . ARG A 1 234 ? 91.357  61.437  88.805  1.00 160.32 ? 234 ARG A O   1 
ATOM 1823 C CB  . ARG A 1 234 ? 92.221  58.750  86.931  1.00 160.32 ? 234 ARG A CB  1 
ATOM 1824 C CG  . ARG A 1 234 ? 92.261  57.234  86.876  1.00 160.32 ? 234 ARG A CG  1 
ATOM 1825 C CD  . ARG A 1 234 ? 93.227  56.650  87.892  1.00 160.32 ? 234 ARG A CD  1 
ATOM 1826 N NE  . ARG A 1 234 ? 94.621  56.811  87.495  1.00 160.32 ? 234 ARG A NE  1 
ATOM 1827 C CZ  . ARG A 1 234 ? 95.435  57.742  87.972  1.00 160.32 ? 234 ARG A CZ  1 
ATOM 1828 N NH1 . ARG A 1 234 ? 95.027  58.623  88.871  1.00 160.32 ? 234 ARG A NH1 1 
ATOM 1829 N NH2 . ARG A 1 234 ? 96.691  57.789  87.538  1.00 160.32 ? 234 ARG A NH2 1 
ATOM 1830 N N   . VAL A 1 235 ? 90.936  61.505  86.595  1.00 154.63 ? 235 VAL A N   1 
ATOM 1831 C CA  . VAL A 1 235 ? 91.045  62.960  86.554  1.00 154.63 ? 235 VAL A CA  1 
ATOM 1832 C C   . VAL A 1 235 ? 89.870  63.616  87.267  1.00 154.63 ? 235 VAL A C   1 
ATOM 1833 O O   . VAL A 1 235 ? 90.050  64.609  87.982  1.00 154.63 ? 235 VAL A O   1 
ATOM 1834 C CB  . VAL A 1 235 ? 91.177  63.453  85.101  1.00 154.63 ? 235 VAL A CB  1 
ATOM 1835 C CG1 . VAL A 1 235 ? 92.566  63.144  84.566  1.00 154.63 ? 235 VAL A CG1 1 
ATOM 1836 C CG2 . VAL A 1 235 ? 90.115  62.821  84.216  1.00 154.63 ? 235 VAL A CG2 1 
ATOM 1837 N N   . ALA A 1 236 ? 88.658  63.085  87.089  1.00 153.42 ? 236 ALA A N   1 
ATOM 1838 C CA  . ALA A 1 236 ? 87.488  63.697  87.712  1.00 153.42 ? 236 ALA A CA  1 
ATOM 1839 C C   . ALA A 1 236 ? 87.584  63.662  89.231  1.00 153.42 ? 236 ALA A C   1 
ATOM 1840 O O   . ALA A 1 236 ? 87.290  64.661  89.899  1.00 153.42 ? 236 ALA A O   1 
ATOM 1841 C CB  . ALA A 1 236 ? 86.214  63.000  87.239  1.00 153.42 ? 236 ALA A CB  1 
ATOM 1842 N N   . ALA A 1 237 ? 87.990  62.522  89.798  1.00 152.04 ? 237 ALA A N   1 
ATOM 1843 C CA  . ALA A 1 237 ? 88.201  62.455  91.240  1.00 152.04 ? 237 ALA A CA  1 
ATOM 1844 C C   . ALA A 1 237 ? 89.309  63.400  91.683  1.00 152.04 ? 237 ALA A C   1 
ATOM 1845 O O   . ALA A 1 237 ? 89.168  64.083  92.703  1.00 152.04 ? 237 ALA A O   1 
ATOM 1846 C CB  . ALA A 1 237 ? 88.523  61.023  91.666  1.00 152.04 ? 237 ALA A CB  1 
ATOM 1847 N N   . LEU A 1 238 ? 90.414  63.448  90.935  1.00 141.32 ? 238 LEU A N   1 
ATOM 1848 C CA  . LEU A 1 238 ? 91.465  64.415  91.231  1.00 141.32 ? 238 LEU A CA  1 
ATOM 1849 C C   . LEU A 1 238 ? 90.963  65.844  91.070  1.00 141.32 ? 238 LEU A C   1 
ATOM 1850 O O   . LEU A 1 238 ? 91.255  66.706  91.906  1.00 141.32 ? 238 LEU A O   1 
ATOM 1851 C CB  . LEU A 1 238 ? 92.675  64.170  90.332  1.00 141.32 ? 238 LEU A CB  1 
ATOM 1852 C CG  . LEU A 1 238 ? 93.520  62.945  90.677  1.00 141.32 ? 238 LEU A CG  1 
ATOM 1853 C CD1 . LEU A 1 238 ? 94.607  62.744  89.642  1.00 141.32 ? 238 LEU A CD1 1 
ATOM 1854 C CD2 . LEU A 1 238 ? 94.121  63.089  92.066  1.00 141.32 ? 238 LEU A CD2 1 
ATOM 1855 N N   . GLN A 1 239 ? 90.208  66.114  89.999  1.00 141.81 ? 239 GLN A N   1 
ATOM 1856 C CA  . GLN A 1 239 ? 89.661  67.452  89.796  1.00 141.81 ? 239 GLN A CA  1 
ATOM 1857 C C   . GLN A 1 239 ? 88.738  67.847  90.941  1.00 141.81 ? 239 GLN A C   1 
ATOM 1858 O O   . GLN A 1 239 ? 88.789  68.984  91.424  1.00 141.81 ? 239 GLN A O   1 
ATOM 1859 C CB  . GLN A 1 239 ? 88.924  67.526  88.459  1.00 141.81 ? 239 GLN A CB  1 
ATOM 1860 C CG  . GLN A 1 239 ? 88.393  68.909  88.117  1.00 141.81 ? 239 GLN A CG  1 
ATOM 1861 C CD  . GLN A 1 239 ? 87.878  69.005  86.696  1.00 141.81 ? 239 GLN A CD  1 
ATOM 1862 O OE1 . GLN A 1 239 ? 86.686  69.206  86.467  1.00 141.81 ? 239 GLN A OE1 1 
ATOM 1863 N NE2 . GLN A 1 239 ? 88.779  68.868  85.729  1.00 141.81 ? 239 GLN A NE2 1 
ATOM 1864 N N   . ASN A 1 240 ? 87.884  66.922  91.386  1.00 154.35 ? 240 ASN A N   1 
ATOM 1865 C CA  . ASN A 1 240 ? 87.110  67.162  92.598  1.00 154.35 ? 240 ASN A CA  1 
ATOM 1866 C C   . ASN A 1 240 ? 88.029  67.349  93.797  1.00 154.35 ? 240 ASN A C   1 
ATOM 1867 O O   . ASN A 1 240 ? 87.793  68.219  94.644  1.00 154.35 ? 240 ASN A O   1 
ATOM 1868 C CB  . ASN A 1 240 ? 86.143  66.005  92.839  1.00 154.35 ? 240 ASN A CB  1 
ATOM 1869 C CG  . ASN A 1 240 ? 85.410  66.125  94.158  1.00 154.35 ? 240 ASN A CG  1 
ATOM 1870 O OD1 . ASN A 1 240 ? 85.044  67.222  94.581  1.00 154.35 ? 240 ASN A OD1 1 
ATOM 1871 N ND2 . ASN A 1 240 ? 85.199  64.995  94.821  1.00 154.35 ? 240 ASN A ND2 1 
ATOM 1872 N N   . LEU A 1 241 ? 89.082  66.533  93.886  1.00 142.35 ? 241 LEU A N   1 
ATOM 1873 C CA  . LEU A 1 241 ? 90.041  66.660  94.978  1.00 142.35 ? 241 LEU A CA  1 
ATOM 1874 C C   . LEU A 1 241 ? 90.766  67.999  94.940  1.00 142.35 ? 241 LEU A C   1 
ATOM 1875 O O   . LEU A 1 241 ? 91.119  68.538  95.996  1.00 142.35 ? 241 LEU A O   1 
ATOM 1876 C CB  . LEU A 1 241 ? 91.042  65.508  94.920  1.00 142.35 ? 241 LEU A CB  1 
ATOM 1877 C CG  . LEU A 1 241 ? 91.953  65.300  96.127  1.00 142.35 ? 241 LEU A CG  1 
ATOM 1878 C CD1 . LEU A 1 241 ? 91.134  65.068  97.384  1.00 142.35 ? 241 LEU A CD1 1 
ATOM 1879 C CD2 . LEU A 1 241 ? 92.870  64.125  95.858  1.00 142.35 ? 241 LEU A CD2 1 
ATOM 1880 N N   . VAL A 1 242 ? 90.999  68.547  93.744  1.00 136.66 ? 242 VAL A N   1 
ATOM 1881 C CA  . VAL A 1 242 ? 91.629  69.861  93.634  1.00 136.66 ? 242 VAL A CA  1 
ATOM 1882 C C   . VAL A 1 242 ? 90.750  70.924  94.282  1.00 136.66 ? 242 VAL A C   1 
ATOM 1883 O O   . VAL A 1 242 ? 91.227  71.772  95.046  1.00 136.66 ? 242 VAL A O   1 
ATOM 1884 C CB  . VAL A 1 242 ? 91.927  70.194  92.160  1.00 136.66 ? 242 VAL A CB  1 
ATOM 1885 C CG1 . VAL A 1 242 ? 92.327  71.654  92.013  1.00 136.66 ? 242 VAL A CG1 1 
ATOM 1886 C CG2 . VAL A 1 242 ? 93.025  69.289  91.619  1.00 136.66 ? 242 VAL A CG2 1 
ATOM 1887 N N   . LYS A 1 243 ? 89.448  70.894  93.984  1.00 144.52 ? 243 LYS A N   1 
ATOM 1888 C CA  . LYS A 1 243 ? 88.530  71.873  94.557  1.00 144.52 ? 243 LYS A CA  1 
ATOM 1889 C C   . LYS A 1 243 ? 88.331  71.658  96.054  1.00 144.52 ? 243 LYS A C   1 
ATOM 1890 O O   . LYS A 1 243 ? 88.093  72.624  96.788  1.00 144.52 ? 243 LYS A O   1 
ATOM 1891 C CB  . LYS A 1 243 ? 87.192  71.827  93.818  1.00 144.52 ? 243 LYS A CB  1 
ATOM 1892 C CG  . LYS A 1 243 ? 86.304  73.036  94.066  1.00 144.52 ? 243 LYS A CG  1 
ATOM 1893 C CD  . LYS A 1 243 ? 85.119  73.066  93.113  1.00 144.52 ? 243 LYS A CD  1 
ATOM 1894 C CE  . LYS A 1 243 ? 85.566  73.320  91.683  1.00 144.52 ? 243 LYS A CE  1 
ATOM 1895 N NZ  . LYS A 1 243 ? 84.424  73.334  90.727  1.00 144.52 ? 243 LYS A NZ  1 
ATOM 1896 N N   . ILE A 1 244 ? 88.413  70.409  96.524  1.00 158.44 ? 244 ILE A N   1 
ATOM 1897 C CA  . ILE A 1 244 ? 88.350  70.149  97.961  1.00 158.44 ? 244 ILE A CA  1 
ATOM 1898 C C   . ILE A 1 244 ? 89.518  70.820  98.671  1.00 158.44 ? 244 ILE A C   1 
ATOM 1899 O O   . ILE A 1 244 ? 89.355  71.425  99.738  1.00 158.44 ? 244 ILE A O   1 
ATOM 1900 C CB  . ILE A 1 244 ? 88.315  68.633  98.234  1.00 158.44 ? 244 ILE A CB  1 
ATOM 1901 C CG1 . ILE A 1 244 ? 86.970  68.044  97.807  1.00 158.44 ? 244 ILE A CG1 1 
ATOM 1902 C CG2 . ILE A 1 244 ? 88.574  68.343  99.706  1.00 158.44 ? 244 ILE A CG2 1 
ATOM 1903 C CD1 . ILE A 1 244 ? 85.794  68.547  98.626  1.00 158.44 ? 244 ILE A CD1 1 
ATOM 1904 N N   . MET A 1 245 ? 90.715  70.722  98.089  1.00 154.76 ? 245 MET A N   1 
ATOM 1905 C CA  . MET A 1 245 ? 91.881  71.385  98.663  1.00 154.76 ? 245 MET A CA  1 
ATOM 1906 C C   . MET A 1 245 ? 91.708  72.900  98.675  1.00 154.76 ? 245 MET A C   1 
ATOM 1907 O O   . MET A 1 245 ? 92.073  73.566  99.651  1.00 154.76 ? 245 MET A O   1 
ATOM 1908 C CB  . MET A 1 245 ? 93.134  70.987  97.882  1.00 154.76 ? 245 MET A CB  1 
ATOM 1909 C CG  . MET A 1 245 ? 94.249  72.016  97.918  1.00 154.76 ? 245 MET A CG  1 
ATOM 1910 S SD  . MET A 1 245 ? 94.961  72.239  99.557  1.00 154.76 ? 245 MET A SD  1 
ATOM 1911 C CE  . MET A 1 245 ? 95.441  73.960  99.463  1.00 154.76 ? 245 MET A CE  1 
ATOM 1912 N N   . SER A 1 246 ? 91.137  73.459  97.605  1.00 157.28 ? 246 SER A N   1 
ATOM 1913 C CA  . SER A 1 246 ? 91.034  74.911  97.481  1.00 157.28 ? 246 SER A CA  1 
ATOM 1914 C C   . SER A 1 246 ? 90.176  75.529  98.580  1.00 157.28 ? 246 SER A C   1 
ATOM 1915 O O   . SER A 1 246 ? 90.391  76.688  98.950  1.00 157.28 ? 246 SER A O   1 
ATOM 1916 C CB  . SER A 1 246 ? 90.475  75.279  96.108  1.00 157.28 ? 246 SER A CB  1 
ATOM 1917 O OG  . SER A 1 246 ? 89.140  74.825  95.963  1.00 157.28 ? 246 SER A OG  1 
ATOM 1918 N N   . LEU A 1 247 ? 89.204  74.784  99.106  1.00 154.56 ? 247 LEU A N   1 
ATOM 1919 C CA  . LEU A 1 247 ? 88.270  75.330  100.084 1.00 154.56 ? 247 LEU A CA  1 
ATOM 1920 C C   . LEU A 1 247 ? 88.623  74.951  101.518 1.00 154.56 ? 247 LEU A C   1 
ATOM 1921 O O   . LEU A 1 247 ? 88.670  75.822  102.393 1.00 154.56 ? 247 LEU A O   1 
ATOM 1922 C CB  . LEU A 1 247 ? 86.844  74.865  99.766  1.00 154.56 ? 247 LEU A CB  1 
ATOM 1923 C CG  . LEU A 1 247 ? 86.259  75.259  98.408  1.00 154.56 ? 247 LEU A CG  1 
ATOM 1924 C CD1 . LEU A 1 247 ? 84.863  74.678  98.236  1.00 154.56 ? 247 LEU A CD1 1 
ATOM 1925 C CD2 . LEU A 1 247 ? 86.236  76.771  98.246  1.00 154.56 ? 247 LEU A CD2 1 
ATOM 1926 N N   . TYR A 1 248 ? 88.871  73.669  101.779 1.00 167.73 ? 248 TYR A N   1 
ATOM 1927 C CA  . TYR A 1 248 ? 88.951  73.168  103.146 1.00 167.73 ? 248 TYR A CA  1 
ATOM 1928 C C   . TYR A 1 248 ? 90.381  72.878  103.584 1.00 167.73 ? 248 TYR A C   1 
ATOM 1929 O O   . TYR A 1 248 ? 90.625  71.907  104.307 1.00 167.73 ? 248 TYR A O   1 
ATOM 1930 C CB  . TYR A 1 248 ? 88.087  71.915  103.287 1.00 167.73 ? 248 TYR A CB  1 
ATOM 1931 C CG  . TYR A 1 248 ? 86.635  72.160  102.951 1.00 167.73 ? 248 TYR A CG  1 
ATOM 1932 C CD1 . TYR A 1 248 ? 86.034  73.376  103.252 1.00 167.73 ? 248 TYR A CD1 1 
ATOM 1933 C CD2 . TYR A 1 248 ? 85.869  71.186  102.323 1.00 167.73 ? 248 TYR A CD2 1 
ATOM 1934 C CE1 . TYR A 1 248 ? 84.711  73.614  102.946 1.00 167.73 ? 248 TYR A CE1 1 
ATOM 1935 C CE2 . TYR A 1 248 ? 84.541  71.416  102.012 1.00 167.73 ? 248 TYR A CE2 1 
ATOM 1936 C CZ  . TYR A 1 248 ? 83.970  72.632  102.326 1.00 167.73 ? 248 TYR A CZ  1 
ATOM 1937 O OH  . TYR A 1 248 ? 82.651  72.873  102.022 1.00 167.73 ? 248 TYR A OH  1 
ATOM 1938 N N   . TYR A 1 249 ? 91.329  73.716  103.155 1.00 170.15 ? 249 TYR A N   1 
ATOM 1939 C CA  . TYR A 1 249 ? 92.733  73.523  103.507 1.00 170.15 ? 249 TYR A CA  1 
ATOM 1940 C C   . TYR A 1 249 ? 92.970  73.517  105.013 1.00 170.15 ? 249 TYR A C   1 
ATOM 1941 O O   . TYR A 1 249 ? 93.946  72.915  105.472 1.00 170.15 ? 249 TYR A O   1 
ATOM 1942 C CB  . TYR A 1 249 ? 93.583  74.613  102.847 1.00 170.15 ? 249 TYR A CB  1 
ATOM 1943 C CG  . TYR A 1 249 ? 95.025  74.645  103.302 1.00 170.15 ? 249 TYR A CG  1 
ATOM 1944 C CD1 . TYR A 1 249 ? 95.937  73.704  102.846 1.00 170.15 ? 249 TYR A CD1 1 
ATOM 1945 C CD2 . TYR A 1 249 ? 95.474  75.621  104.181 1.00 170.15 ? 249 TYR A CD2 1 
ATOM 1946 C CE1 . TYR A 1 249 ? 97.253  73.732  103.254 1.00 170.15 ? 249 TYR A CE1 1 
ATOM 1947 C CE2 . TYR A 1 249 ? 96.789  75.656  104.596 1.00 170.15 ? 249 TYR A CE2 1 
ATOM 1948 C CZ  . TYR A 1 249 ? 97.675  74.709  104.130 1.00 170.15 ? 249 TYR A CZ  1 
ATOM 1949 O OH  . TYR A 1 249 ? 98.986  74.741  104.543 1.00 170.15 ? 249 TYR A OH  1 
ATOM 1950 N N   . GLN A 1 250 ? 92.098  74.162  105.792 1.00 174.32 ? 250 GLN A N   1 
ATOM 1951 C CA  . GLN A 1 250 ? 92.284  74.237  107.237 1.00 174.32 ? 250 GLN A CA  1 
ATOM 1952 C C   . GLN A 1 250 ? 92.132  72.893  107.938 1.00 174.32 ? 250 GLN A C   1 
ATOM 1953 O O   . GLN A 1 250 ? 92.497  72.788  109.113 1.00 174.32 ? 250 GLN A O   1 
ATOM 1954 C CB  . GLN A 1 250 ? 91.294  75.236  107.841 1.00 174.32 ? 250 GLN A CB  1 
ATOM 1955 C CG  . GLN A 1 250 ? 91.668  76.693  107.629 1.00 174.32 ? 250 GLN A CG  1 
ATOM 1956 C CD  . GLN A 1 250 ? 92.878  77.107  108.445 1.00 174.32 ? 250 GLN A CD  1 
ATOM 1957 O OE1 . GLN A 1 250 ? 94.001  77.134  107.941 1.00 174.32 ? 250 GLN A OE1 1 
ATOM 1958 N NE2 . GLN A 1 250 ? 92.653  77.435  109.712 1.00 174.32 ? 250 GLN A NE2 1 
ATOM 1959 N N   . TYR A 1 251 ? 91.615  71.867  107.258 1.00 176.88 ? 251 TYR A N   1 
ATOM 1960 C CA  . TYR A 1 251 ? 91.349  70.585  107.897 1.00 176.88 ? 251 TYR A CA  1 
ATOM 1961 C C   . TYR A 1 251 ? 91.833  69.373  107.112 1.00 176.88 ? 251 TYR A C   1 
ATOM 1962 O O   . TYR A 1 251 ? 91.478  68.248  107.481 1.00 176.88 ? 251 TYR A O   1 
ATOM 1963 C CB  . TYR A 1 251 ? 89.845  70.428  108.175 1.00 176.88 ? 251 TYR A CB  1 
ATOM 1964 C CG  . TYR A 1 251 ? 89.298  71.444  109.156 1.00 176.88 ? 251 TYR A CG  1 
ATOM 1965 C CD1 . TYR A 1 251 ? 89.250  71.169  110.516 1.00 176.88 ? 251 TYR A CD1 1 
ATOM 1966 C CD2 . TYR A 1 251 ? 88.833  72.678  108.720 1.00 176.88 ? 251 TYR A CD2 1 
ATOM 1967 C CE1 . TYR A 1 251 ? 88.752  72.095  111.415 1.00 176.88 ? 251 TYR A CE1 1 
ATOM 1968 C CE2 . TYR A 1 251 ? 88.335  73.610  109.610 1.00 176.88 ? 251 TYR A CE2 1 
ATOM 1969 C CZ  . TYR A 1 251 ? 88.296  73.313  110.956 1.00 176.88 ? 251 TYR A CZ  1 
ATOM 1970 O OH  . TYR A 1 251 ? 87.801  74.237  111.849 1.00 176.88 ? 251 TYR A OH  1 
ATOM 1971 N N   . MET A 1 252 ? 92.611  69.557  106.046 1.00 172.44 ? 252 MET A N   1 
ATOM 1972 C CA  . MET A 1 252 ? 93.153  68.448  105.268 1.00 172.44 ? 252 MET A CA  1 
ATOM 1973 C C   . MET A 1 252 ? 94.466  67.907  105.830 1.00 172.44 ? 252 MET A C   1 
ATOM 1974 O O   . MET A 1 252 ? 95.105  67.076  105.174 1.00 172.44 ? 252 MET A O   1 
ATOM 1975 C CB  . MET A 1 252 ? 93.353  68.876  103.811 1.00 172.44 ? 252 MET A CB  1 
ATOM 1976 C CG  . MET A 1 252 ? 92.087  69.366  103.127 1.00 172.44 ? 252 MET A CG  1 
ATOM 1977 S SD  . MET A 1 252 ? 90.764  68.140  103.112 1.00 172.44 ? 252 MET A SD  1 
ATOM 1978 C CE  . MET A 1 252 ? 91.503  66.857  102.106 1.00 172.44 ? 252 MET A CE  1 
ATOM 1979 N N   . GLU A 1 253 ? 94.887  68.369  107.010 1.00 186.25 ? 253 GLU A N   1 
ATOM 1980 C CA  . GLU A 1 253 ? 96.196  67.996  107.541 1.00 186.25 ? 253 GLU A CA  1 
ATOM 1981 C C   . GLU A 1 253 ? 96.291  66.512  107.877 1.00 186.25 ? 253 GLU A C   1 
ATOM 1982 O O   . GLU A 1 253 ? 97.310  65.877  107.583 1.00 186.25 ? 253 GLU A O   1 
ATOM 1983 C CB  . GLU A 1 253 ? 96.512  68.841  108.777 1.00 186.25 ? 253 GLU A CB  1 
ATOM 1984 C CG  . GLU A 1 253 ? 97.865  68.553  109.415 1.00 186.25 ? 253 GLU A CG  1 
ATOM 1985 C CD  . GLU A 1 253 ? 97.789  67.507  110.511 1.00 186.25 ? 253 GLU A CD  1 
ATOM 1986 O OE1 . GLU A 1 253 ? 96.663  67.164  110.931 1.00 186.25 ? 253 GLU A OE1 1 
ATOM 1987 O OE2 . GLU A 1 253 ? 98.854  67.027  110.953 1.00 186.25 ? 253 GLU A OE2 1 
ATOM 1988 N N   . THR A 1 254 ? 95.250  65.943  108.487 1.00 184.72 ? 254 THR A N   1 
ATOM 1989 C CA  . THR A 1 254 ? 95.344  64.603  109.057 1.00 184.72 ? 254 THR A CA  1 
ATOM 1990 C C   . THR A 1 254 ? 95.496  63.507  108.007 1.00 184.72 ? 254 THR A C   1 
ATOM 1991 O O   . THR A 1 254 ? 95.827  62.373  108.368 1.00 184.72 ? 254 THR A O   1 
ATOM 1992 C CB  . THR A 1 254 ? 94.110  64.319  109.918 1.00 184.72 ? 254 THR A CB  1 
ATOM 1993 O OG1 . THR A 1 254 ? 93.662  65.535  110.528 1.00 184.72 ? 254 THR A OG1 1 
ATOM 1994 C CG2 . THR A 1 254 ? 94.438  63.311  111.015 1.00 184.72 ? 254 THR A CG2 1 
ATOM 1995 N N   . TYR A 1 255 ? 95.278  63.809  106.728 1.00 176.97 ? 255 TYR A N   1 
ATOM 1996 C CA  . TYR A 1 255 ? 95.262  62.781  105.698 1.00 176.97 ? 255 TYR A CA  1 
ATOM 1997 C C   . TYR A 1 255 ? 96.208  63.056  104.537 1.00 176.97 ? 255 TYR A C   1 
ATOM 1998 O O   . TYR A 1 255 ? 96.307  62.215  103.637 1.00 176.97 ? 255 TYR A O   1 
ATOM 1999 C CB  . TYR A 1 255 ? 93.835  62.600  105.158 1.00 176.97 ? 255 TYR A CB  1 
ATOM 2000 C CG  . TYR A 1 255 ? 92.810  63.416  105.911 1.00 176.97 ? 255 TYR A CG  1 
ATOM 2001 C CD1 . TYR A 1 255 ? 92.225  62.932  107.073 1.00 176.97 ? 255 TYR A CD1 1 
ATOM 2002 C CD2 . TYR A 1 255 ? 92.434  64.675  105.463 1.00 176.97 ? 255 TYR A CD2 1 
ATOM 2003 C CE1 . TYR A 1 255 ? 91.292  63.677  107.767 1.00 176.97 ? 255 TYR A CE1 1 
ATOM 2004 C CE2 . TYR A 1 255 ? 91.502  65.427  106.149 1.00 176.97 ? 255 TYR A CE2 1 
ATOM 2005 C CZ  . TYR A 1 255 ? 90.935  64.925  107.301 1.00 176.97 ? 255 TYR A CZ  1 
ATOM 2006 O OH  . TYR A 1 255 ? 90.005  65.671  107.988 1.00 176.97 ? 255 TYR A OH  1 
ATOM 2007 N N   . MET A 1 256 ? 96.904  64.196  104.531 1.00 166.69 ? 256 MET A N   1 
ATOM 2008 C CA  . MET A 1 256 ? 97.772  64.533  103.407 1.00 166.69 ? 256 MET A CA  1 
ATOM 2009 C C   . MET A 1 256 ? 98.860  63.484  103.208 1.00 166.69 ? 256 MET A C   1 
ATOM 2010 O O   . MET A 1 256 ? 99.112  63.046  102.080 1.00 166.69 ? 256 MET A O   1 
ATOM 2011 C CB  . MET A 1 256 ? 98.388  65.916  103.617 1.00 166.69 ? 256 MET A CB  1 
ATOM 2012 C CG  . MET A 1 256 ? 99.499  66.271  102.637 1.00 166.69 ? 256 MET A CG  1 
ATOM 2013 S SD  . MET A 1 256 ? 101.147 65.934  103.293 1.00 166.69 ? 256 MET A SD  1 
ATOM 2014 C CE  . MET A 1 256 ? 102.178 66.611  101.995 1.00 166.69 ? 256 MET A CE  1 
ATOM 2015 N N   . GLY A 1 257 ? 99.508  63.066  104.290 1.00 171.25 ? 257 GLY A N   1 
ATOM 2016 C CA  . GLY A 1 257 ? 100.557 62.077  104.218 1.00 171.25 ? 257 GLY A CA  1 
ATOM 2017 C C   . GLY A 1 257 ? 100.057 60.692  103.854 1.00 171.25 ? 257 GLY A C   1 
ATOM 2018 O O   . GLY A 1 257 ? 100.376 60.152  102.790 1.00 171.25 ? 257 GLY A O   1 
ATOM 2019 N N   . PRO A 1 258 ? 99.267  60.082  104.743 1.00 165.03 ? 258 PRO A N   1 
ATOM 2020 C CA  . PRO A 1 258 ? 98.811  58.705  104.494 1.00 165.03 ? 258 PRO A CA  1 
ATOM 2021 C C   . PRO A 1 258 ? 97.946  58.541  103.253 1.00 165.03 ? 258 PRO A C   1 
ATOM 2022 O O   . PRO A 1 258 ? 97.925  57.442  102.685 1.00 165.03 ? 258 PRO A O   1 
ATOM 2023 C CB  . PRO A 1 258 ? 98.025  58.357  105.768 1.00 165.03 ? 258 PRO A CB  1 
ATOM 2024 C CG  . PRO A 1 258 ? 97.686  59.677  106.389 1.00 165.03 ? 258 PRO A CG  1 
ATOM 2025 C CD  . PRO A 1 258 ? 98.832  60.576  106.060 1.00 165.03 ? 258 PRO A CD  1 
ATOM 2026 N N   . ALA A 1 259 ? 97.237  59.576  102.806 1.00 167.89 ? 259 ALA A N   1 
ATOM 2027 C CA  . ALA A 1 259 ? 96.250  59.394  101.751 1.00 167.89 ? 259 ALA A CA  1 
ATOM 2028 C C   . ALA A 1 259 ? 96.414  60.312  100.549 1.00 167.89 ? 259 ALA A C   1 
ATOM 2029 O O   . ALA A 1 259 ? 96.217  59.855  99.421  1.00 167.89 ? 259 ALA A O   1 
ATOM 2030 C CB  . ALA A 1 259 ? 94.832  59.577  102.314 1.00 167.89 ? 259 ALA A CB  1 
ATOM 2031 N N   . LEU A 1 260 ? 96.773  61.581  100.743 1.00 159.40 ? 260 LEU A N   1 
ATOM 2032 C CA  . LEU A 1 260 ? 96.712  62.564  99.664  1.00 159.40 ? 260 LEU A CA  1 
ATOM 2033 C C   . LEU A 1 260 ? 98.013  62.660  98.873  1.00 159.40 ? 260 LEU A C   1 
ATOM 2034 O O   . LEU A 1 260 ? 98.007  62.509  97.648  1.00 159.40 ? 260 LEU A O   1 
ATOM 2035 C CB  . LEU A 1 260 ? 96.330  63.941  100.223 1.00 159.40 ? 260 LEU A CB  1 
ATOM 2036 C CG  . LEU A 1 260 ? 94.837  64.233  100.401 1.00 159.40 ? 260 LEU A CG  1 
ATOM 2037 C CD1 . LEU A 1 260 ? 94.068  63.802  99.169  1.00 159.40 ? 260 LEU A CD1 1 
ATOM 2038 C CD2 . LEU A 1 260 ? 94.272  63.566  101.640 1.00 159.40 ? 260 LEU A CD2 1 
ATOM 2039 N N   . PHE A 1 261 ? 99.134  62.916  99.555  1.00 151.59 ? 261 PHE A N   1 
ATOM 2040 C CA  . PHE A 1 261 ? 100.375 63.214  98.846  1.00 151.59 ? 261 PHE A CA  1 
ATOM 2041 C C   . PHE A 1 261 ? 100.898 62.012  98.068  1.00 151.59 ? 261 PHE A C   1 
ATOM 2042 O O   . PHE A 1 261 ? 101.659 62.185  97.109  1.00 151.59 ? 261 PHE A O   1 
ATOM 2043 C CB  . PHE A 1 261 ? 101.430 63.723  99.833  1.00 151.59 ? 261 PHE A CB  1 
ATOM 2044 C CG  . PHE A 1 261 ? 102.530 62.739  100.118 1.00 151.59 ? 261 PHE A CG  1 
ATOM 2045 C CD1 . PHE A 1 261 ? 102.351 61.727  101.045 1.00 151.59 ? 261 PHE A CD1 1 
ATOM 2046 C CD2 . PHE A 1 261 ? 103.752 62.840  99.473  1.00 151.59 ? 261 PHE A CD2 1 
ATOM 2047 C CE1 . PHE A 1 261 ? 103.362 60.824  101.312 1.00 151.59 ? 261 PHE A CE1 1 
ATOM 2048 C CE2 . PHE A 1 261 ? 104.767 61.941  99.736  1.00 151.59 ? 261 PHE A CE2 1 
ATOM 2049 C CZ  . PHE A 1 261 ? 104.572 60.932  100.658 1.00 151.59 ? 261 PHE A CZ  1 
ATOM 2050 N N   . ALA A 1 262 ? 100.514 60.796  98.460  1.00 150.46 ? 262 ALA A N   1 
ATOM 2051 C CA  . ALA A 1 262 ? 100.946 59.617  97.715  1.00 150.46 ? 262 ALA A CA  1 
ATOM 2052 C C   . ALA A 1 262 ? 100.316 59.578  96.328  1.00 150.46 ? 262 ALA A C   1 
ATOM 2053 O O   . ALA A 1 262 ? 100.972 59.202  95.349  1.00 150.46 ? 262 ALA A O   1 
ATOM 2054 C CB  . ALA A 1 262 ? 100.608 58.348  98.497  1.00 150.46 ? 262 ALA A CB  1 
ATOM 2055 N N   . ILE A 1 263 ? 99.042  59.961  96.226  1.00 151.86 ? 263 ILE A N   1 
ATOM 2056 C CA  . ILE A 1 263 ? 98.350  59.928  94.941  1.00 151.86 ? 263 ILE A CA  1 
ATOM 2057 C C   . ILE A 1 263 ? 98.885  61.009  94.010  1.00 151.86 ? 263 ILE A C   1 
ATOM 2058 O O   . ILE A 1 263 ? 99.101  60.768  92.816  1.00 151.86 ? 263 ILE A O   1 
ATOM 2059 C CB  . ILE A 1 263 ? 96.832  60.070  95.154  1.00 151.86 ? 263 ILE A CB  1 
ATOM 2060 C CG1 . ILE A 1 263 ? 96.320  58.985  96.101  1.00 151.86 ? 263 ILE A CG1 1 
ATOM 2061 C CG2 . ILE A 1 263 ? 96.096  60.016  93.822  1.00 151.86 ? 263 ILE A CG2 1 
ATOM 2062 C CD1 . ILE A 1 263 ? 94.863  59.142  96.464  1.00 151.86 ? 263 ILE A CD1 1 
ATOM 2063 N N   . THR A 1 264 ? 99.100  62.218  94.538  1.00 151.88 ? 264 THR A N   1 
ATOM 2064 C CA  . THR A 1 264 ? 99.466  63.353  93.695  1.00 151.88 ? 264 THR A CA  1 
ATOM 2065 C C   . THR A 1 264 ? 100.787 63.117  92.976  1.00 151.88 ? 264 THR A C   1 
ATOM 2066 O O   . THR A 1 264 ? 100.910 63.411  91.780  1.00 151.88 ? 264 THR A O   1 
ATOM 2067 C CB  . THR A 1 264 ? 99.542  64.627  94.536  1.00 151.88 ? 264 THR A CB  1 
ATOM 2068 O OG1 . THR A 1 264 ? 100.640 64.530  95.451  1.00 151.88 ? 264 THR A OG1 1 
ATOM 2069 C CG2 . THR A 1 264 ? 98.255  64.813  95.319  1.00 151.88 ? 264 THR A CG2 1 
ATOM 2070 N N   . ILE A 1 265 ? 101.793 62.608  93.689  1.00 147.67 ? 265 ILE A N   1 
ATOM 2071 C CA  . ILE A 1 265 ? 103.070 62.308  93.049  1.00 147.67 ? 265 ILE A CA  1 
ATOM 2072 C C   . ILE A 1 265 ? 102.899 61.217  91.998  1.00 147.67 ? 265 ILE A C   1 
ATOM 2073 O O   . ILE A 1 265 ? 103.439 61.315  90.890  1.00 147.67 ? 265 ILE A O   1 
ATOM 2074 C CB  . ILE A 1 265 ? 104.121 61.925  94.105  1.00 147.67 ? 265 ILE A CB  1 
ATOM 2075 C CG1 . ILE A 1 265 ? 104.268 63.050  95.129  1.00 147.67 ? 265 ILE A CG1 1 
ATOM 2076 C CG2 . ILE A 1 265 ? 105.457 61.635  93.442  1.00 147.67 ? 265 ILE A CG2 1 
ATOM 2077 C CD1 . ILE A 1 265 ? 105.342 62.803  96.160  1.00 147.67 ? 265 ILE A CD1 1 
ATOM 2078 N N   . GLU A 1 266 ? 102.149 60.161  92.326  1.00 159.08 ? 266 GLU A N   1 
ATOM 2079 C CA  . GLU A 1 266 ? 101.885 59.110  91.349  1.00 159.08 ? 266 GLU A CA  1 
ATOM 2080 C C   . GLU A 1 266 ? 101.100 59.634  90.154  1.00 159.08 ? 266 GLU A C   1 
ATOM 2081 O O   . GLU A 1 266 ? 101.406 59.279  89.010  1.00 159.08 ? 266 GLU A O   1 
ATOM 2082 C CB  . GLU A 1 266 ? 101.137 57.952  92.012  1.00 159.08 ? 266 GLU A CB  1 
ATOM 2083 C CG  . GLU A 1 266 ? 100.392 57.039  91.045  1.00 159.08 ? 266 GLU A CG  1 
ATOM 2084 C CD  . GLU A 1 266 ? 101.314 56.290  90.100  1.00 159.08 ? 266 GLU A CD  1 
ATOM 2085 O OE1 . GLU A 1 266 ? 102.479 56.037  90.473  1.00 159.08 ? 266 GLU A OE1 1 
ATOM 2086 O OE2 . GLU A 1 266 ? 100.870 55.955  88.981  1.00 159.08 ? 266 GLU A OE2 1 
ATOM 2087 N N   . ALA A 1 267 ? 100.095 60.478  90.395  1.00 145.60 ? 267 ALA A N   1 
ATOM 2088 C CA  . ALA A 1 267 ? 99.299  61.012  89.295  1.00 145.60 ? 267 ALA A CA  1 
ATOM 2089 C C   . ALA A 1 267 ? 100.121 61.950  88.421  1.00 145.60 ? 267 ALA A C   1 
ATOM 2090 O O   . ALA A 1 267 ? 99.802  62.149  87.243  1.00 145.60 ? 267 ALA A O   1 
ATOM 2091 C CB  . ALA A 1 267 ? 98.066  61.729  89.839  1.00 145.60 ? 267 ALA A CB  1 
ATOM 2092 N N   . MET A 1 268 ? 101.185 62.531  88.978  1.00 131.57 ? 268 MET A N   1 
ATOM 2093 C CA  . MET A 1 268 ? 102.026 63.443  88.215  1.00 131.57 ? 268 MET A CA  1 
ATOM 2094 C C   . MET A 1 268 ? 103.029 62.701  87.343  1.00 131.57 ? 268 MET A C   1 
ATOM 2095 O O   . MET A 1 268 ? 103.600 63.299  86.425  1.00 131.57 ? 268 MET A O   1 
ATOM 2096 C CB  . MET A 1 268 ? 102.753 64.392  89.172  1.00 131.57 ? 268 MET A CB  1 
ATOM 2097 C CG  . MET A 1 268 ? 103.396 65.601  88.512  1.00 131.57 ? 268 MET A CG  1 
ATOM 2098 S SD  . MET A 1 268 ? 104.149 66.704  89.723  1.00 131.57 ? 268 MET A SD  1 
ATOM 2099 C CE  . MET A 1 268 ? 102.718 67.136  90.709  1.00 131.57 ? 268 MET A CE  1 
ATOM 2100 N N   . LYS A 1 269 ? 103.243 61.408  87.598  1.00 141.79 ? 269 LYS A N   1 
ATOM 2101 C CA  . LYS A 1 269 ? 104.154 60.609  86.789  1.00 141.79 ? 269 LYS A CA  1 
ATOM 2102 C C   . LYS A 1 269 ? 103.494 60.055  85.534  1.00 141.79 ? 269 LYS A C   1 
ATOM 2103 O O   . LYS A 1 269 ? 104.181 59.420  84.726  1.00 141.79 ? 269 LYS A O   1 
ATOM 2104 C CB  . LYS A 1 269 ? 104.714 59.449  87.616  1.00 141.79 ? 269 LYS A CB  1 
ATOM 2105 C CG  . LYS A 1 269 ? 105.476 59.869  88.860  1.00 141.79 ? 269 LYS A CG  1 
ATOM 2106 C CD  . LYS A 1 269 ? 105.808 58.674  89.738  1.00 141.79 ? 269 LYS A CD  1 
ATOM 2107 C CE  . LYS A 1 269 ? 106.540 59.104  90.999  1.00 141.79 ? 269 LYS A CE  1 
ATOM 2108 N NZ  . LYS A 1 269 ? 106.782 57.964  91.926  1.00 141.79 ? 269 LYS A NZ  1 
ATOM 2109 N N   . SER A 1 270 ? 102.193 60.271  85.359  1.00 140.95 ? 270 SER A N   1 
ATOM 2110 C CA  . SER A 1 270 ? 101.474 59.695  84.232  1.00 140.95 ? 270 SER A CA  1 
ATOM 2111 C C   . SER A 1 270 ? 101.982 60.252  82.908  1.00 140.95 ? 270 SER A C   1 
ATOM 2112 O O   . SER A 1 270 ? 102.251 61.450  82.779  1.00 140.95 ? 270 SER A O   1 
ATOM 2113 C CB  . SER A 1 270 ? 99.976  59.966  84.367  1.00 140.95 ? 270 SER A CB  1 
ATOM 2114 O OG  . SER A 1 270 ? 99.261  59.446  83.260  1.00 140.95 ? 270 SER A OG  1 
ATOM 2115 N N   . ASP A 1 271 ? 102.113 59.367  81.920  1.00 149.66 ? 271 ASP A N   1 
ATOM 2116 C CA  . ASP A 1 271 ? 102.453 59.770  80.563  1.00 149.66 ? 271 ASP A CA  1 
ATOM 2117 C C   . ASP A 1 271 ? 101.274 60.381  79.819  1.00 149.66 ? 271 ASP A C   1 
ATOM 2118 O O   . ASP A 1 271 ? 101.460 60.900  78.713  1.00 149.66 ? 271 ASP A O   1 
ATOM 2119 C CB  . ASP A 1 271 ? 102.991 58.568  79.782  1.00 149.66 ? 271 ASP A CB  1 
ATOM 2120 C CG  . ASP A 1 271 ? 102.141 57.328  79.969  1.00 149.66 ? 271 ASP A CG  1 
ATOM 2121 O OD1 . ASP A 1 271 ? 101.014 57.291  79.433  1.00 149.66 ? 271 ASP A OD1 1 
ATOM 2122 O OD2 . ASP A 1 271 ? 102.599 56.392  80.658  1.00 149.66 ? 271 ASP A OD2 1 
ATOM 2123 N N   . ILE A 1 272 ? 100.076 60.326  80.391  1.00 145.80 ? 272 ILE A N   1 
ATOM 2124 C CA  . ILE A 1 272 ? 98.905  60.944  79.783  1.00 145.80 ? 272 ILE A CA  1 
ATOM 2125 C C   . ILE A 1 272 ? 98.864  62.415  80.173  1.00 145.80 ? 272 ILE A C   1 
ATOM 2126 O O   . ILE A 1 272 ? 99.461  62.837  81.170  1.00 145.80 ? 272 ILE A O   1 
ATOM 2127 C CB  . ILE A 1 272 ? 97.620  60.204  80.205  1.00 145.80 ? 272 ILE A CB  1 
ATOM 2128 C CG1 . ILE A 1 272 ? 97.860  58.694  80.229  1.00 145.80 ? 272 ILE A CG1 1 
ATOM 2129 C CG2 . ILE A 1 272 ? 96.474  60.519  79.253  1.00 145.80 ? 272 ILE A CG2 1 
ATOM 2130 C CD1 . ILE A 1 272 ? 96.659  57.899  80.686  1.00 145.80 ? 272 ILE A CD1 1 
ATOM 2131 N N   . ASP A 1 273 ? 98.148  63.209  79.376  1.00 148.40 ? 273 ASP A N   1 
ATOM 2132 C CA  . ASP A 1 273 ? 98.172  64.657  79.556  1.00 148.40 ? 273 ASP A CA  1 
ATOM 2133 C C   . ASP A 1 273 ? 97.368  65.079  80.779  1.00 148.40 ? 273 ASP A C   1 
ATOM 2134 O O   . ASP A 1 273 ? 97.902  65.713  81.697  1.00 148.40 ? 273 ASP A O   1 
ATOM 2135 C CB  . ASP A 1 273 ? 97.637  65.342  78.299  1.00 148.40 ? 273 ASP A CB  1 
ATOM 2136 C CG  . ASP A 1 273 ? 98.130  64.685  77.024  1.00 148.40 ? 273 ASP A CG  1 
ATOM 2137 O OD1 . ASP A 1 273 ? 98.857  63.673  77.117  1.00 148.40 ? 273 ASP A OD1 1 
ATOM 2138 O OD2 . ASP A 1 273 ? 97.790  65.176  75.929  1.00 148.40 ? 273 ASP A OD2 1 
ATOM 2139 N N   . GLU A 1 274 ? 96.078  64.736  80.807  1.00 147.71 ? 274 GLU A N   1 
ATOM 2140 C CA  . GLU A 1 274 ? 95.191  65.246  81.849  1.00 147.71 ? 274 GLU A CA  1 
ATOM 2141 C C   . GLU A 1 274 ? 95.587  64.743  83.232  1.00 147.71 ? 274 GLU A C   1 
ATOM 2142 O O   . GLU A 1 274 ? 95.538  65.501  84.207  1.00 147.71 ? 274 GLU A O   1 
ATOM 2143 C CB  . GLU A 1 274 ? 93.743  64.868  81.538  1.00 147.71 ? 274 GLU A CB  1 
ATOM 2144 C CG  . GLU A 1 274 ? 93.121  65.648  80.390  1.00 147.71 ? 274 GLU A CG  1 
ATOM 2145 C CD  . GLU A 1 274 ? 93.601  65.183  79.029  1.00 147.71 ? 274 GLU A CD  1 
ATOM 2146 O OE1 . GLU A 1 274 ? 94.250  64.118  78.955  1.00 147.71 ? 274 GLU A OE1 1 
ATOM 2147 O OE2 . GLU A 1 274 ? 93.326  65.883  78.032  1.00 147.71 ? 274 GLU A OE2 1 
ATOM 2148 N N   . VAL A 1 275 ? 95.972  63.469  83.341  1.00 133.40 ? 275 VAL A N   1 
ATOM 2149 C CA  . VAL A 1 275 ? 96.274  62.893  84.650  1.00 133.40 ? 275 VAL A CA  1 
ATOM 2150 C C   . VAL A 1 275 ? 97.447  63.620  85.297  1.00 133.40 ? 275 VAL A C   1 
ATOM 2151 O O   . VAL A 1 275 ? 97.413  63.949  86.489  1.00 133.40 ? 275 VAL A O   1 
ATOM 2152 C CB  . VAL A 1 275 ? 96.546  61.383  84.523  1.00 133.40 ? 275 VAL A CB  1 
ATOM 2153 C CG1 . VAL A 1 275 ? 96.768  60.770  85.898  1.00 133.40 ? 275 VAL A CG1 1 
ATOM 2154 C CG2 . VAL A 1 275 ? 95.394  60.695  83.807  1.00 133.40 ? 275 VAL A CG2 1 
ATOM 2155 N N   . ALA A 1 276 ? 98.505  63.875  84.524  1.00 121.11 ? 276 ALA A N   1 
ATOM 2156 C CA  . ALA A 1 276 ? 99.633  64.637  85.047  1.00 121.11 ? 276 ALA A CA  1 
ATOM 2157 C C   . ALA A 1 276 ? 99.277  66.106  85.239  1.00 121.11 ? 276 ALA A C   1 
ATOM 2158 O O   . ALA A 1 276 ? 99.772  66.745  86.175  1.00 121.11 ? 276 ALA A O   1 
ATOM 2159 C CB  . ALA A 1 276 ? 100.840 64.499  84.121  1.00 121.11 ? 276 ALA A CB  1 
ATOM 2160 N N   . LEU A 1 277 ? 98.435  66.658  84.360  1.00 119.36 ? 277 LEU A N   1 
ATOM 2161 C CA  . LEU A 1 277 ? 98.060  68.064  84.475  1.00 119.36 ? 277 LEU A CA  1 
ATOM 2162 C C   . LEU A 1 277 ? 97.287  68.332  85.760  1.00 119.36 ? 277 LEU A C   1 
ATOM 2163 O O   . LEU A 1 277 ? 97.593  69.283  86.489  1.00 119.36 ? 277 LEU A O   1 
ATOM 2164 C CB  . LEU A 1 277 ? 97.235  68.489  83.261  1.00 119.36 ? 277 LEU A CB  1 
ATOM 2165 C CG  . LEU A 1 277 ? 96.688  69.917  83.301  1.00 119.36 ? 277 LEU A CG  1 
ATOM 2166 C CD1 . LEU A 1 277 ? 97.821  70.921  83.361  1.00 119.36 ? 277 LEU A CD1 1 
ATOM 2167 C CD2 . LEU A 1 277 ? 95.787  70.189  82.103  1.00 119.36 ? 277 LEU A CD2 1 
ATOM 2168 N N   . GLN A 1 278 ? 96.275  67.510  86.050  1.00 122.17 ? 278 GLN A N   1 
ATOM 2169 C CA  . GLN A 1 278 ? 95.482  67.719  87.256  1.00 122.17 ? 278 GLN A CA  1 
ATOM 2170 C C   . GLN A 1 278 ? 96.319  67.544  88.516  1.00 122.17 ? 278 GLN A C   1 
ATOM 2171 O O   . GLN A 1 278 ? 96.141  68.295  89.482  1.00 122.17 ? 278 GLN A O   1 
ATOM 2172 C CB  . GLN A 1 278 ? 94.280  66.774  87.273  1.00 122.17 ? 278 GLN A CB  1 
ATOM 2173 C CG  . GLN A 1 278 ? 93.352  66.931  86.076  1.00 122.17 ? 278 GLN A CG  1 
ATOM 2174 C CD  . GLN A 1 278 ? 92.779  68.330  85.955  1.00 122.17 ? 278 GLN A CD  1 
ATOM 2175 O OE1 . GLN A 1 278 ? 92.621  69.038  86.949  1.00 122.17 ? 278 GLN A OE1 1 
ATOM 2176 N NE2 . GLN A 1 278 ? 92.461  68.735  84.731  1.00 122.17 ? 278 GLN A NE2 1 
ATOM 2177 N N   . GLY A 1 279 ? 97.220  66.559  88.534  1.00 121.70 ? 279 GLY A N   1 
ATOM 2178 C CA  . GLY A 1 279 ? 98.136  66.433  89.655  1.00 121.70 ? 279 GLY A CA  1 
ATOM 2179 C C   . GLY A 1 279 ? 99.021  67.655  89.815  1.00 121.70 ? 279 GLY A C   1 
ATOM 2180 O O   . GLY A 1 279 ? 99.235  68.137  90.931  1.00 121.70 ? 279 GLY A O   1 
ATOM 2181 N N   . ILE A 1 280 ? 99.542  68.174  88.701  1.00 122.56 ? 280 ILE A N   1 
ATOM 2182 C CA  . ILE A 1 280 ? 100.298 69.422  88.739  1.00 122.56 ? 280 ILE A CA  1 
ATOM 2183 C C   . ILE A 1 280 ? 99.407  70.566  89.205  1.00 122.56 ? 280 ILE A C   1 
ATOM 2184 O O   . ILE A 1 280 ? 99.827  71.417  89.999  1.00 122.56 ? 280 ILE A O   1 
ATOM 2185 C CB  . ILE A 1 280 ? 100.931 69.703  87.361  1.00 122.56 ? 280 ILE A CB  1 
ATOM 2186 C CG1 . ILE A 1 280 ? 102.370 69.192  87.329  1.00 122.56 ? 280 ILE A CG1 1 
ATOM 2187 C CG2 . ILE A 1 280 ? 100.900 71.187  87.030  1.00 122.56 ? 280 ILE A CG2 1 
ATOM 2188 C CD1 . ILE A 1 280 ? 103.264 69.871  88.336  1.00 122.56 ? 280 ILE A CD1 1 
ATOM 2189 N N   . GLU A 1 281 ? 98.160  70.598  88.730  1.00 127.92 ? 281 GLU A N   1 
ATOM 2190 C CA  . GLU A 1 281 ? 97.230  71.634  89.163  1.00 127.92 ? 281 GLU A CA  1 
ATOM 2191 C C   . GLU A 1 281 ? 96.945  71.533  90.657  1.00 127.92 ? 281 GLU A C   1 
ATOM 2192 O O   . GLU A 1 281 ? 96.794  72.557  91.335  1.00 127.92 ? 281 GLU A O   1 
ATOM 2193 C CB  . GLU A 1 281 ? 95.933  71.544  88.358  1.00 127.92 ? 281 GLU A CB  1 
ATOM 2194 C CG  . GLU A 1 281 ? 94.915  72.630  88.678  1.00 127.92 ? 281 GLU A CG  1 
ATOM 2195 C CD  . GLU A 1 281 ? 95.326  73.997  88.161  1.00 127.92 ? 281 GLU A CD  1 
ATOM 2196 O OE1 . GLU A 1 281 ? 96.267  74.072  87.342  1.00 127.92 ? 281 GLU A OE1 1 
ATOM 2197 O OE2 . GLU A 1 281 ? 94.705  74.999  88.574  1.00 127.92 ? 281 GLU A OE2 1 
ATOM 2198 N N   . PHE A 1 282 ? 96.861  70.309  91.184  1.00 138.93 ? 282 PHE A N   1 
ATOM 2199 C CA  . PHE A 1 282 ? 96.546  70.123  92.598  1.00 138.93 ? 282 PHE A CA  1 
ATOM 2200 C C   . PHE A 1 282 ? 97.599  70.768  93.492  1.00 138.93 ? 282 PHE A C   1 
ATOM 2201 O O   . PHE A 1 282 ? 97.272  71.557  94.387  1.00 138.93 ? 282 PHE A O   1 
ATOM 2202 C CB  . PHE A 1 282 ? 96.417  68.632  92.914  1.00 138.93 ? 282 PHE A CB  1 
ATOM 2203 C CG  . PHE A 1 282 ? 96.049  68.344  94.343  1.00 138.93 ? 282 PHE A CG  1 
ATOM 2204 C CD1 . PHE A 1 282 ? 94.723  68.329  94.740  1.00 138.93 ? 282 PHE A CD1 1 
ATOM 2205 C CD2 . PHE A 1 282 ? 97.028  68.087  95.290  1.00 138.93 ? 282 PHE A CD2 1 
ATOM 2206 C CE1 . PHE A 1 282 ? 94.380  68.065  96.052  1.00 138.93 ? 282 PHE A CE1 1 
ATOM 2207 C CE2 . PHE A 1 282 ? 96.691  67.824  96.603  1.00 138.93 ? 282 PHE A CE2 1 
ATOM 2208 C CZ  . PHE A 1 282 ? 95.366  67.812  96.984  1.00 138.93 ? 282 PHE A CZ  1 
ATOM 2209 N N   . TRP A 1 283 ? 98.874  70.444  93.264  1.00 140.86 ? 283 TRP A N   1 
ATOM 2210 C CA  . TRP A 1 283 ? 99.923  70.969  94.132  1.00 140.86 ? 283 TRP A CA  1 
ATOM 2211 C C   . TRP A 1 283 ? 100.180 72.447  93.879  1.00 140.86 ? 283 TRP A C   1 
ATOM 2212 O O   . TRP A 1 283 ? 100.734 73.133  94.745  1.00 140.86 ? 283 TRP A O   1 
ATOM 2213 C CB  . TRP A 1 283 ? 101.211 70.164  93.956  1.00 140.86 ? 283 TRP A CB  1 
ATOM 2214 C CG  . TRP A 1 283 ? 101.475 69.224  95.095  1.00 140.86 ? 283 TRP A CG  1 
ATOM 2215 C CD1 . TRP A 1 283 ? 101.330 67.867  95.091  1.00 140.86 ? 283 TRP A CD1 1 
ATOM 2216 C CD2 . TRP A 1 283 ? 101.916 69.576  96.413  1.00 140.86 ? 283 TRP A CD2 1 
ATOM 2217 N NE1 . TRP A 1 283 ? 101.661 67.352  96.322  1.00 140.86 ? 283 TRP A NE1 1 
ATOM 2218 C CE2 . TRP A 1 283 ? 102.022 68.381  97.151  1.00 140.86 ? 283 TRP A CE2 1 
ATOM 2219 C CE3 . TRP A 1 283 ? 102.233 70.785  97.039  1.00 140.86 ? 283 TRP A CE3 1 
ATOM 2220 C CZ2 . TRP A 1 283 ? 102.433 68.360  98.482  1.00 140.86 ? 283 TRP A CZ2 1 
ATOM 2221 C CZ3 . TRP A 1 283 ? 102.641 70.762  98.360  1.00 140.86 ? 283 TRP A CZ3 1 
ATOM 2222 C CH2 . TRP A 1 283 ? 102.736 69.558  99.067  1.00 140.86 ? 283 TRP A CH2 1 
ATOM 2223 N N   . SER A 1 284 ? 99.790  72.957  92.709  1.00 141.59 ? 284 SER A N   1 
ATOM 2224 C CA  . SER A 1 284 ? 99.889  74.393  92.474  1.00 141.59 ? 284 SER A CA  1 
ATOM 2225 C C   . SER A 1 284 ? 98.928  75.155  93.377  1.00 141.59 ? 284 SER A C   1 
ATOM 2226 O O   . SER A 1 284 ? 99.269  76.223  93.898  1.00 141.59 ? 284 SER A O   1 
ATOM 2227 C CB  . SER A 1 284 ? 99.617  74.711  91.005  1.00 141.59 ? 284 SER A CB  1 
ATOM 2228 O OG  . SER A 1 284 ? 98.270  74.437  90.661  1.00 141.59 ? 284 SER A OG  1 
ATOM 2229 N N   . ASN A 1 285 ? 97.721  74.617  93.572  1.00 140.71 ? 285 ASN A N   1 
ATOM 2230 C CA  . ASN A 1 285 ? 96.765  75.240  94.479  1.00 140.71 ? 285 ASN A CA  1 
ATOM 2231 C C   . ASN A 1 285 ? 97.242  75.194  95.924  1.00 140.71 ? 285 ASN A C   1 
ATOM 2232 O O   . ASN A 1 285 ? 96.948  76.112  96.698  1.00 140.71 ? 285 ASN A O   1 
ATOM 2233 C CB  . ASN A 1 285 ? 95.400  74.566  94.349  1.00 140.71 ? 285 ASN A CB  1 
ATOM 2234 C CG  . ASN A 1 285 ? 94.704  74.914  93.052  1.00 140.71 ? 285 ASN A CG  1 
ATOM 2235 O OD1 . ASN A 1 285 ? 95.338  75.355  92.094  1.00 140.71 ? 285 ASN A OD1 1 
ATOM 2236 N ND2 . ASN A 1 285 ? 93.391  74.724  93.016  1.00 140.71 ? 285 ASN A ND2 1 
ATOM 2237 N N   . VAL A 1 286 ? 97.957  74.135  96.311  1.00 146.35 ? 286 VAL A N   1 
ATOM 2238 C CA  . VAL A 1 286 ? 98.494  74.058  97.668  1.00 146.35 ? 286 VAL A CA  1 
ATOM 2239 C C   . VAL A 1 286 ? 99.449  75.217  97.928  1.00 146.35 ? 286 VAL A C   1 
ATOM 2240 O O   . VAL A 1 286 ? 99.372  75.889  98.963  1.00 146.35 ? 286 VAL A O   1 
ATOM 2241 C CB  . VAL A 1 286 ? 99.178  72.699  97.901  1.00 146.35 ? 286 VAL A CB  1 
ATOM 2242 C CG1 . VAL A 1 286 ? 99.715  72.618  99.321  1.00 146.35 ? 286 VAL A CG1 1 
ATOM 2243 C CG2 . VAL A 1 286 ? 98.200  71.561  97.631  1.00 146.35 ? 286 VAL A CG2 1 
ATOM 2244 N N   . CYS A 1 287 ? 100.370 75.463  96.993  1.00 153.33 ? 287 CYS A N   1 
ATOM 2245 C CA  . CYS A 1 287 ? 101.261 76.611  97.115  1.00 153.33 ? 287 CYS A CA  1 
ATOM 2246 C C   . CYS A 1 287 ? 100.499 77.925  97.005  1.00 153.33 ? 287 CYS A C   1 
ATOM 2247 O O   . CYS A 1 287 ? 100.827 78.890  97.705  1.00 153.33 ? 287 CYS A O   1 
ATOM 2248 C CB  . CYS A 1 287 ? 102.357 76.543  96.052  1.00 153.33 ? 287 CYS A CB  1 
ATOM 2249 S SG  . CYS A 1 287 ? 102.387 77.949  94.920  1.00 153.33 ? 287 CYS A SG  1 
ATOM 2250 N N   . ASP A 1 288 ? 99.493  77.985  96.129  1.00 157.32 ? 288 ASP A N   1 
ATOM 2251 C CA  . ASP A 1 288 ? 98.723  79.214  95.965  1.00 157.32 ? 288 ASP A CA  1 
ATOM 2252 C C   . ASP A 1 288 ? 97.994  79.586  97.250  1.00 157.32 ? 288 ASP A C   1 
ATOM 2253 O O   . ASP A 1 288 ? 98.102  80.724  97.723  1.00 157.32 ? 288 ASP A O   1 
ATOM 2254 C CB  . ASP A 1 288 ? 97.735  79.060  94.808  1.00 157.32 ? 288 ASP A CB  1 
ATOM 2255 C CG  . ASP A 1 288 ? 97.244  80.394  94.272  1.00 157.32 ? 288 ASP A CG  1 
ATOM 2256 O OD1 . ASP A 1 288 ? 96.972  81.309  95.076  1.00 157.32 ? 288 ASP A OD1 1 
ATOM 2257 O OD2 . ASP A 1 288 ? 97.132  80.527  93.036  1.00 157.32 ? 288 ASP A OD2 1 
ATOM 2258 N N   . GLU A 1 289 ? 97.249  78.643  97.832  1.00 159.22 ? 289 GLU A N   1 
ATOM 2259 C CA  . GLU A 1 289 ? 96.555  78.929  99.083  1.00 159.22 ? 289 GLU A CA  1 
ATOM 2260 C C   . GLU A 1 289 ? 97.536  79.108  100.233 1.00 159.22 ? 289 GLU A C   1 
ATOM 2261 O O   . GLU A 1 289 ? 97.223  79.794  101.213 1.00 159.22 ? 289 GLU A O   1 
ATOM 2262 C CB  . GLU A 1 289 ? 95.550  77.819  99.395  1.00 159.22 ? 289 GLU A CB  1 
ATOM 2263 C CG  . GLU A 1 289 ? 94.541  78.180  100.477 1.00 159.22 ? 289 GLU A CG  1 
ATOM 2264 C CD  . GLU A 1 289 ? 93.365  77.222  100.529 1.00 159.22 ? 289 GLU A CD  1 
ATOM 2265 O OE1 . GLU A 1 289 ? 93.278  76.333  99.657  1.00 159.22 ? 289 GLU A OE1 1 
ATOM 2266 O OE2 . GLU A 1 289 ? 92.525  77.360  101.442 1.00 159.22 ? 289 GLU A OE2 1 
ATOM 2267 N N   . GLU A 1 290 ? 98.722  78.501  100.134 1.00 166.09 ? 290 GLU A N   1 
ATOM 2268 C CA  . GLU A 1 290 ? 99.765  78.753  101.122 1.00 166.09 ? 290 GLU A CA  1 
ATOM 2269 C C   . GLU A 1 290 ? 100.200 80.212  101.089 1.00 166.09 ? 290 GLU A C   1 
ATOM 2270 O O   . GLU A 1 290 ? 100.401 80.834  102.138 1.00 166.09 ? 290 GLU A O   1 
ATOM 2271 C CB  . GLU A 1 290 ? 100.961 77.835  100.871 1.00 166.09 ? 290 GLU A CB  1 
ATOM 2272 C CG  . GLU A 1 290 ? 101.571 77.232  102.125 1.00 166.09 ? 290 GLU A CG  1 
ATOM 2273 C CD  . GLU A 1 290 ? 101.016 75.855  102.439 1.00 166.09 ? 290 GLU A CD  1 
ATOM 2274 O OE1 . GLU A 1 290 ? 100.209 75.340  101.639 1.00 166.09 ? 290 GLU A OE1 1 
ATOM 2275 O OE2 . GLU A 1 290 ? 101.389 75.287  103.487 1.00 166.09 ? 290 GLU A OE2 1 
ATOM 2276 N N   . MET A 1 291 ? 100.352 80.773  99.886  1.00 168.17 ? 291 MET A N   1 
ATOM 2277 C CA  . MET A 1 291 ? 100.718 82.179  99.755  1.00 168.17 ? 291 MET A CA  1 
ATOM 2278 C C   . MET A 1 291 ? 99.653  83.091  100.349 1.00 168.17 ? 291 MET A C   1 
ATOM 2279 O O   . MET A 1 291 ? 99.975  84.023  101.096 1.00 168.17 ? 291 MET A O   1 
ATOM 2280 C CB  . MET A 1 291 ? 100.953 82.523  98.284  1.00 168.17 ? 291 MET A CB  1 
ATOM 2281 C CG  . MET A 1 291 ? 102.414 82.720  97.918  1.00 168.17 ? 291 MET A CG  1 
ATOM 2282 S SD  . MET A 1 291 ? 103.156 84.130  98.762  1.00 168.17 ? 291 MET A SD  1 
ATOM 2283 C CE  . MET A 1 291 ? 104.796 84.131  98.042  1.00 168.17 ? 291 MET A CE  1 
ATOM 2284 N N   . ASP A 1 292 ? 98.381  82.844  100.026 1.00 172.72 ? 292 ASP A N   1 
ATOM 2285 C CA  . ASP A 1 292 ? 97.308  83.661  100.586 1.00 172.72 ? 292 ASP A CA  1 
ATOM 2286 C C   . ASP A 1 292 ? 97.248  83.520  102.101 1.00 172.72 ? 292 ASP A C   1 
ATOM 2287 O O   . ASP A 1 292 ? 97.022  84.505  102.814 1.00 172.72 ? 292 ASP A O   1 
ATOM 2288 C CB  . ASP A 1 292 ? 95.968  83.282  99.956  1.00 172.72 ? 292 ASP A CB  1 
ATOM 2289 C CG  . ASP A 1 292 ? 95.914  83.588  98.473  1.00 172.72 ? 292 ASP A CG  1 
ATOM 2290 O OD1 . ASP A 1 292 ? 96.958  83.980  97.909  1.00 172.72 ? 292 ASP A OD1 1 
ATOM 2291 O OD2 . ASP A 1 292 ? 94.830  83.441  97.871  1.00 172.72 ? 292 ASP A OD2 1 
ATOM 2292 N N   . LEU A 1 293 ? 97.439  82.302  102.610 1.00 175.84 ? 293 LEU A N   1 
ATOM 2293 C CA  . LEU A 1 293 ? 97.542  82.121  104.052 1.00 175.84 ? 293 LEU A CA  1 
ATOM 2294 C C   . LEU A 1 293 ? 98.795  82.788  104.604 1.00 175.84 ? 293 LEU A C   1 
ATOM 2295 O O   . LEU A 1 293 ? 98.763  83.348  105.706 1.00 175.84 ? 293 LEU A O   1 
ATOM 2296 C CB  . LEU A 1 293 ? 97.516  80.634  104.400 1.00 175.84 ? 293 LEU A CB  1 
ATOM 2297 C CG  . LEU A 1 293 ? 97.280  80.288  105.870 1.00 175.84 ? 293 LEU A CG  1 
ATOM 2298 C CD1 . LEU A 1 293 ? 96.349  81.302  106.507 1.00 175.84 ? 293 LEU A CD1 1 
ATOM 2299 C CD2 . LEU A 1 293 ? 96.695  78.894  105.988 1.00 175.84 ? 293 LEU A CD2 1 
ATOM 2300 N N   . ALA A 1 294 ? 99.903  82.740  103.858 1.00 178.04 ? 294 ALA A N   1 
ATOM 2301 C CA  . ALA A 1 294 ? 101.093 83.483  104.258 1.00 178.04 ? 294 ALA A CA  1 
ATOM 2302 C C   . ALA A 1 294 ? 100.818 84.981  104.289 1.00 178.04 ? 294 ALA A C   1 
ATOM 2303 O O   . ALA A 1 294 ? 101.352 85.699  105.142 1.00 178.04 ? 294 ALA A O   1 
ATOM 2304 C CB  . ALA A 1 294 ? 102.256 83.170  103.317 1.00 178.04 ? 294 ALA A CB  1 
ATOM 2305 N N   . ILE A 1 295 ? 99.996  85.470  103.356 1.00 185.50 ? 295 ILE A N   1 
ATOM 2306 C CA  . ILE A 1 295 ? 99.559  86.862  103.408 1.00 185.50 ? 295 ILE A CA  1 
ATOM 2307 C C   . ILE A 1 295 ? 98.763  87.116  104.680 1.00 185.50 ? 295 ILE A C   1 
ATOM 2308 O O   . ILE A 1 295 ? 98.979  88.114  105.379 1.00 185.50 ? 295 ILE A O   1 
ATOM 2309 C CB  . ILE A 1 295 ? 98.745  87.218  102.149 1.00 185.50 ? 295 ILE A CB  1 
ATOM 2310 C CG1 . ILE A 1 295 ? 99.650  87.237  100.916 1.00 185.50 ? 295 ILE A CG1 1 
ATOM 2311 C CG2 . ILE A 1 295 ? 98.043  88.559  102.321 1.00 185.50 ? 295 ILE A CG2 1 
ATOM 2312 C CD1 . ILE A 1 295 ? 100.786 88.236  101.006 1.00 185.50 ? 295 ILE A CD1 1 
ATOM 2313 N N   . GLU A 1 296 ? 97.835  86.212  105.006 1.00 194.55 ? 296 GLU A N   1 
ATOM 2314 C CA  . GLU A 1 296 ? 97.099  86.328  106.261 1.00 194.55 ? 296 GLU A CA  1 
ATOM 2315 C C   . GLU A 1 296 ? 98.036  86.216  107.456 1.00 194.55 ? 296 GLU A C   1 
ATOM 2316 O O   . GLU A 1 296 ? 97.884  86.948  108.442 1.00 194.55 ? 296 GLU A O   1 
ATOM 2317 C CB  . GLU A 1 296 ? 96.007  85.261  106.330 1.00 194.55 ? 296 GLU A CB  1 
ATOM 2318 C CG  . GLU A 1 296 ? 95.191  85.288  107.612 1.00 194.55 ? 296 GLU A CG  1 
ATOM 2319 C CD  . GLU A 1 296 ? 94.155  84.182  107.669 1.00 194.55 ? 296 GLU A CD  1 
ATOM 2320 O OE1 . GLU A 1 296 ? 93.952  83.500  106.643 1.00 194.55 ? 296 GLU A OE1 1 
ATOM 2321 O OE2 . GLU A 1 296 ? 93.545  83.993  108.742 1.00 194.55 ? 296 GLU A OE2 1 
ATOM 2322 N N   . ALA A 1 297 ? 99.008  85.303  107.388 1.00 199.40 ? 297 ALA A N   1 
ATOM 2323 C CA  . ALA A 1 297 ? 100.000 85.197  108.453 1.00 199.40 ? 297 ALA A CA  1 
ATOM 2324 C C   . ALA A 1 297 ? 100.809 86.481  108.581 1.00 199.40 ? 297 ALA A C   1 
ATOM 2325 O O   . ALA A 1 297 ? 101.072 86.947  109.695 1.00 199.40 ? 297 ALA A O   1 
ATOM 2326 C CB  . ALA A 1 297 ? 100.919 84.003  108.198 1.00 199.40 ? 297 ALA A CB  1 
ATOM 2327 N N   . SER A 1 298 ? 101.215 87.066  107.451 1.00 202.60 ? 298 SER A N   1 
ATOM 2328 C CA  . SER A 1 298 ? 101.918 88.344  107.492 1.00 202.60 ? 298 SER A CA  1 
ATOM 2329 C C   . SER A 1 298 ? 101.014 89.452  108.018 1.00 202.60 ? 298 SER A C   1 
ATOM 2330 O O   . SER A 1 298 ? 101.465 90.320  108.773 1.00 202.60 ? 298 SER A O   1 
ATOM 2331 C CB  . SER A 1 298 ? 102.453 88.697  106.105 1.00 202.60 ? 298 SER A CB  1 
ATOM 2332 O OG  . SER A 1 298 ? 101.393 88.913  105.189 1.00 202.60 ? 298 SER A OG  1 
ATOM 2333 N N   . GLU A 1 299 ? 99.738  89.441  107.623 1.00 214.96 ? 299 GLU A N   1 
ATOM 2334 C CA  . GLU A 1 299 ? 98.797  90.439  108.123 1.00 214.96 ? 299 GLU A CA  1 
ATOM 2335 C C   . GLU A 1 299 ? 98.618  90.325  109.631 1.00 214.96 ? 299 GLU A C   1 
ATOM 2336 O O   . GLU A 1 299 ? 98.567  91.339  110.337 1.00 214.96 ? 299 GLU A O   1 
ATOM 2337 C CB  . GLU A 1 299 ? 97.450  90.294  107.413 1.00 214.96 ? 299 GLU A CB  1 
ATOM 2338 C CG  . GLU A 1 299 ? 97.421  90.842  105.994 1.00 214.96 ? 299 GLU A CG  1 
ATOM 2339 C CD  . GLU A 1 299 ? 97.386  92.357  105.952 1.00 214.96 ? 299 GLU A CD  1 
ATOM 2340 O OE1 . GLU A 1 299 ? 97.092  92.978  106.996 1.00 214.96 ? 299 GLU A OE1 1 
ATOM 2341 O OE2 . GLU A 1 299 ? 97.651  92.930  104.874 1.00 214.96 ? 299 GLU A OE2 1 
ATOM 2342 N N   . ALA A 1 300 ? 98.518  89.097  110.144 1.00 217.89 ? 300 ALA A N   1 
ATOM 2343 C CA  . ALA A 1 300 ? 98.321  88.911  111.577 1.00 217.89 ? 300 ALA A CA  1 
ATOM 2344 C C   . ALA A 1 300 ? 99.605  89.150  112.362 1.00 217.89 ? 300 ALA A C   1 
ATOM 2345 O O   . ALA A 1 300 ? 99.548  89.594  113.514 1.00 217.89 ? 300 ALA A O   1 
ATOM 2346 C CB  . ALA A 1 300 ? 97.781  87.509  111.855 1.00 217.89 ? 300 ALA A CB  1 
ATOM 2347 N N   . ALA A 1 301 ? 100.763 88.855  111.766 1.00 223.11 ? 301 ALA A N   1 
ATOM 2348 C CA  . ALA A 1 301 ? 102.027 89.030  112.476 1.00 223.11 ? 301 ALA A CA  1 
ATOM 2349 C C   . ALA A 1 301 ? 102.286 90.496  112.805 1.00 223.11 ? 301 ALA A C   1 
ATOM 2350 O O   . ALA A 1 301 ? 102.673 90.824  113.933 1.00 223.11 ? 301 ALA A O   1 
ATOM 2351 C CB  . ALA A 1 301 ? 103.177 88.454  111.652 1.00 223.11 ? 301 ALA A CB  1 
ATOM 2352 N N   . GLU A 1 302 ? 102.085 91.391  111.834 1.00 231.33 ? 302 GLU A N   1 
ATOM 2353 C CA  . GLU A 1 302 ? 102.333 92.809  112.079 1.00 231.33 ? 302 GLU A CA  1 
ATOM 2354 C C   . GLU A 1 302 ? 101.322 93.400  113.054 1.00 231.33 ? 302 GLU A C   1 
ATOM 2355 O O   . GLU A 1 302 ? 101.689 94.227  113.897 1.00 231.33 ? 302 GLU A O   1 
ATOM 2356 C CB  . GLU A 1 302 ? 102.335 93.582  110.759 1.00 231.33 ? 302 GLU A CB  1 
ATOM 2357 C CG  . GLU A 1 302 ? 101.152 93.300  109.847 1.00 231.33 ? 302 GLU A CG  1 
ATOM 2358 C CD  . GLU A 1 302 ? 100.013 94.281  110.036 1.00 231.33 ? 302 GLU A CD  1 
ATOM 2359 O OE1 . GLU A 1 302 ? 100.144 95.196  110.876 1.00 231.33 ? 302 GLU A OE1 1 
ATOM 2360 O OE2 . GLU A 1 302 ? 98.986  94.138  109.340 1.00 231.33 ? 302 GLU A OE2 1 
ATOM 2361 N N   . GLN A 1 303 ? 100.052 93.001  112.957 1.00 228.16 ? 303 GLN A N   1 
ATOM 2362 C CA  . GLN A 1 303 ? 99.042  93.478  113.893 1.00 228.16 ? 303 GLN A CA  1 
ATOM 2363 C C   . GLN A 1 303 ? 99.229  92.917  115.296 1.00 228.16 ? 303 GLN A C   1 
ATOM 2364 O O   . GLN A 1 303 ? 98.746  93.522  116.259 1.00 228.16 ? 303 GLN A O   1 
ATOM 2365 C CB  . GLN A 1 303 ? 97.642  93.124  113.387 1.00 228.16 ? 303 GLN A CB  1 
ATOM 2366 C CG  . GLN A 1 303 ? 97.249  93.816  112.094 1.00 228.16 ? 303 GLN A CG  1 
ATOM 2367 C CD  . GLN A 1 303 ? 95.865  93.416  111.619 1.00 228.16 ? 303 GLN A CD  1 
ATOM 2368 O OE1 . GLN A 1 303 ? 95.219  92.550  112.210 1.00 228.16 ? 303 GLN A OE1 1 
ATOM 2369 N NE2 . GLN A 1 303 ? 95.402  94.049  110.547 1.00 228.16 ? 303 GLN A NE2 1 
ATOM 2370 N N   . GLY A 1 304 ? 99.918  91.785  115.432 1.00 223.22 ? 304 GLY A N   1 
ATOM 2371 C CA  . GLY A 1 304 ? 100.125 91.152  116.715 1.00 223.22 ? 304 GLY A CA  1 
ATOM 2372 C C   . GLY A 1 304 ? 99.059  90.158  117.121 1.00 223.22 ? 304 GLY A C   1 
ATOM 2373 O O   . GLY A 1 304 ? 99.260  89.423  118.096 1.00 223.22 ? 304 GLY A O   1 
ATOM 2374 N N   . ARG A 1 305 ? 97.935  90.108  116.410 1.00 218.59 ? 305 ARG A N   1 
ATOM 2375 C CA  . ARG A 1 305 ? 96.894  89.142  116.719 1.00 218.59 ? 305 ARG A CA  1 
ATOM 2376 C C   . ARG A 1 305 ? 97.309  87.745  116.262 1.00 218.59 ? 305 ARG A C   1 
ATOM 2377 O O   . ARG A 1 305 ? 98.098  87.600  115.323 1.00 218.59 ? 305 ARG A O   1 
ATOM 2378 C CB  . ARG A 1 305 ? 95.584  89.535  116.044 1.00 218.59 ? 305 ARG A CB  1 
ATOM 2379 C CG  . ARG A 1 305 ? 95.649  89.558  114.524 1.00 218.59 ? 305 ARG A CG  1 
ATOM 2380 C CD  . ARG A 1 305 ? 94.281  89.811  113.914 1.00 218.59 ? 305 ARG A CD  1 
ATOM 2381 N NE  . ARG A 1 305 ? 93.312  88.796  114.313 1.00 218.59 ? 305 ARG A NE  1 
ATOM 2382 C CZ  . ARG A 1 305 ? 93.107  87.659  113.662 1.00 218.59 ? 305 ARG A CZ  1 
ATOM 2383 N NH1 . ARG A 1 305 ? 93.788  87.354  112.570 1.00 218.59 ? 305 ARG A NH1 1 
ATOM 2384 N NH2 . ARG A 1 305 ? 92.195  86.805  114.120 1.00 218.59 ? 305 ARG A NH2 1 
ATOM 2385 N N   . PRO A 1 306 ? 96.806  86.703  116.920 1.00 220.75 ? 306 PRO A N   1 
ATOM 2386 C CA  . PRO A 1 306 ? 97.061  85.351  116.437 1.00 220.75 ? 306 PRO A CA  1 
ATOM 2387 C C   . PRO A 1 306 ? 96.449  85.152  115.068 1.00 220.75 ? 306 PRO A C   1 
ATOM 2388 O O   . PRO A 1 306 ? 95.380  85.712  114.756 1.00 220.75 ? 306 PRO A O   1 
ATOM 2389 C CB  . PRO A 1 306 ? 96.385  84.465  117.493 1.00 220.75 ? 306 PRO A CB  1 
ATOM 2390 C CG  . PRO A 1 306 ? 96.314  85.316  118.714 1.00 220.75 ? 306 PRO A CG  1 
ATOM 2391 C CD  . PRO A 1 306 ? 96.092  86.706  118.208 1.00 220.75 ? 306 PRO A CD  1 
ATOM 2392 N N   . PRO A 1 307 ? 97.091  84.363  114.208 1.00 207.40 ? 307 PRO A N   1 
ATOM 2393 C CA  . PRO A 1 307 ? 96.528  84.119  112.875 1.00 207.40 ? 307 PRO A CA  1 
ATOM 2394 C C   . PRO A 1 307 ? 95.237  83.318  112.957 1.00 207.40 ? 307 PRO A C   1 
ATOM 2395 O O   . PRO A 1 307 ? 95.191  82.236  113.547 1.00 207.40 ? 307 PRO A O   1 
ATOM 2396 C CB  . PRO A 1 307 ? 97.633  83.333  112.159 1.00 207.40 ? 307 PRO A CB  1 
ATOM 2397 C CG  . PRO A 1 307 ? 98.426  82.707  113.260 1.00 207.40 ? 307 PRO A CG  1 
ATOM 2398 C CD  . PRO A 1 307 ? 98.381  83.679  114.403 1.00 207.40 ? 307 PRO A CD  1 
ATOM 2399 N N   . GLU A 1 308 ? 94.178  83.871  112.360 1.00 196.30 ? 308 GLU A N   1 
ATOM 2400 C CA  . GLU A 1 308 ? 92.887  83.189  112.359 1.00 196.30 ? 308 GLU A CA  1 
ATOM 2401 C C   . GLU A 1 308 ? 92.969  81.859  111.621 1.00 196.30 ? 308 GLU A C   1 
ATOM 2402 O O   . GLU A 1 308 ? 92.241  80.913  111.947 1.00 196.30 ? 308 GLU A O   1 
ATOM 2403 C CB  . GLU A 1 308 ? 91.819  84.089  111.736 1.00 196.30 ? 308 GLU A CB  1 
ATOM 2404 C CG  . GLU A 1 308 ? 90.402  83.549  111.852 1.00 196.30 ? 308 GLU A CG  1 
ATOM 2405 C CD  . GLU A 1 308 ? 89.919  83.485  113.288 1.00 196.30 ? 308 GLU A CD  1 
ATOM 2406 O OE1 . GLU A 1 308 ? 90.399  84.289  114.115 1.00 196.30 ? 308 GLU A OE1 1 
ATOM 2407 O OE2 . GLU A 1 308 ? 89.062  82.628  113.592 1.00 196.30 ? 308 GLU A OE2 1 
ATOM 2408 N N   . HIS A 1 309 ? 93.848  81.767  110.627 1.00 188.83 ? 309 HIS A N   1 
ATOM 2409 C CA  . HIS A 1 309 ? 94.119  80.522  109.927 1.00 188.83 ? 309 HIS A CA  1 
ATOM 2410 C C   . HIS A 1 309 ? 95.625  80.312  109.874 1.00 188.83 ? 309 HIS A C   1 
ATOM 2411 O O   . HIS A 1 309 ? 96.397  81.272  109.799 1.00 188.83 ? 309 HIS A O   1 
ATOM 2412 C CB  . HIS A 1 309 ? 93.532  80.527  108.508 1.00 188.83 ? 309 HIS A CB  1 
ATOM 2413 C CG  . HIS A 1 309 ? 92.097  80.949  108.447 1.00 188.83 ? 309 HIS A CG  1 
ATOM 2414 N ND1 . HIS A 1 309 ? 91.700  82.261  108.589 1.00 188.83 ? 309 HIS A ND1 1 
ATOM 2415 C CD2 . HIS A 1 309 ? 90.964  80.232  108.256 1.00 188.83 ? 309 HIS A CD2 1 
ATOM 2416 C CE1 . HIS A 1 309 ? 90.385  82.334  108.489 1.00 188.83 ? 309 HIS A CE1 1 
ATOM 2417 N NE2 . HIS A 1 309 ? 89.914  81.117  108.287 1.00 188.83 ? 309 HIS A NE2 1 
ATOM 2418 N N   . THR A 1 310 ? 96.039  79.048  109.917 1.00 187.04 ? 310 THR A N   1 
ATOM 2419 C CA  . THR A 1 310 ? 97.451  78.695  110.001 1.00 187.04 ? 310 THR A CA  1 
ATOM 2420 C C   . THR A 1 310 ? 97.757  77.589  109.003 1.00 187.04 ? 310 THR A C   1 
ATOM 2421 O O   . THR A 1 310 ? 96.969  76.650  108.850 1.00 187.04 ? 310 THR A O   1 
ATOM 2422 C CB  . THR A 1 310 ? 97.825  78.247  111.420 1.00 187.04 ? 310 THR A CB  1 
ATOM 2423 O OG1 . THR A 1 310 ? 97.417  79.247  112.362 1.00 187.04 ? 310 THR A OG1 1 
ATOM 2424 C CG2 . THR A 1 310 ? 99.329  78.032  111.540 1.00 187.04 ? 310 THR A CG2 1 
ATOM 2425 N N   . SER A 1 311 ? 98.898  77.704  108.330 1.00 178.47 ? 311 SER A N   1 
ATOM 2426 C CA  . SER A 1 311 ? 99.330  76.724  107.349 1.00 178.47 ? 311 SER A CA  1 
ATOM 2427 C C   . SER A 1 311 ? 100.175 75.636  108.009 1.00 178.47 ? 311 SER A C   1 
ATOM 2428 O O   . SER A 1 311 ? 100.356 75.605  109.228 1.00 178.47 ? 311 SER A O   1 
ATOM 2429 C CB  . SER A 1 311 ? 100.116 77.403  106.228 1.00 178.47 ? 311 SER A CB  1 
ATOM 2430 O OG  . SER A 1 311 ? 100.681 76.443  105.355 1.00 178.47 ? 311 SER A OG  1 
ATOM 2431 N N   . LYS A 1 312 ? 100.700 74.728  107.177 1.00 173.51 ? 312 LYS A N   1 
ATOM 2432 C CA  . LYS A 1 312 ? 101.509 73.626  107.686 1.00 173.51 ? 312 LYS A CA  1 
ATOM 2433 C C   . LYS A 1 312 ? 102.745 73.357  106.829 1.00 173.51 ? 312 LYS A C   1 
ATOM 2434 O O   . LYS A 1 312 ? 103.398 72.322  107.013 1.00 173.51 ? 312 LYS A O   1 
ATOM 2435 C CB  . LYS A 1 312 ? 100.670 72.349  107.801 1.00 173.51 ? 312 LYS A CB  1 
ATOM 2436 C CG  . LYS A 1 312 ? 99.634  72.381  108.916 1.00 173.51 ? 312 LYS A CG  1 
ATOM 2437 C CD  . LYS A 1 312 ? 98.240  72.066  108.396 1.00 173.51 ? 312 LYS A CD  1 
ATOM 2438 C CE  . LYS A 1 312 ? 97.736  73.149  107.458 1.00 173.51 ? 312 LYS A CE  1 
ATOM 2439 N NZ  . LYS A 1 312 ? 96.383  72.837  106.921 1.00 173.51 ? 312 LYS A NZ  1 
ATOM 2440 N N   . PHE A 1 313 ? 103.078 74.258  105.902 1.00 173.24 ? 313 PHE A N   1 
ATOM 2441 C CA  . PHE A 1 313 ? 104.321 74.203  105.128 1.00 173.24 ? 313 PHE A CA  1 
ATOM 2442 C C   . PHE A 1 313 ? 104.424 72.911  104.309 1.00 173.24 ? 313 PHE A C   1 
ATOM 2443 O O   . PHE A 1 313 ? 105.408 72.171  104.378 1.00 173.24 ? 313 PHE A O   1 
ATOM 2444 C CB  . PHE A 1 313 ? 105.537 74.375  106.045 1.00 173.24 ? 313 PHE A CB  1 
ATOM 2445 C CG  . PHE A 1 313 ? 105.499 75.629  106.873 1.00 173.24 ? 313 PHE A CG  1 
ATOM 2446 C CD1 . PHE A 1 313 ? 106.030 76.811  106.387 1.00 173.24 ? 313 PHE A CD1 1 
ATOM 2447 C CD2 . PHE A 1 313 ? 104.933 75.626  108.138 1.00 173.24 ? 313 PHE A CD2 1 
ATOM 2448 C CE1 . PHE A 1 313 ? 105.998 77.966  107.144 1.00 173.24 ? 313 PHE A CE1 1 
ATOM 2449 C CE2 . PHE A 1 313 ? 104.897 76.779  108.900 1.00 173.24 ? 313 PHE A CE2 1 
ATOM 2450 C CZ  . PHE A 1 313 ? 105.431 77.951  108.402 1.00 173.24 ? 313 PHE A CZ  1 
ATOM 2451 N N   . TYR A 1 314 ? 103.374 72.648  103.528 1.00 169.24 ? 314 TYR A N   1 
ATOM 2452 C CA  . TYR A 1 314 ? 103.377 71.479  102.652 1.00 169.24 ? 314 TYR A CA  1 
ATOM 2453 C C   . TYR A 1 314 ? 104.403 71.615  101.533 1.00 169.24 ? 314 TYR A C   1 
ATOM 2454 O O   . TYR A 1 314 ? 105.106 70.650  101.210 1.00 169.24 ? 314 TYR A O   1 
ATOM 2455 C CB  . TYR A 1 314 ? 101.983 71.257  102.073 1.00 169.24 ? 314 TYR A CB  1 
ATOM 2456 C CG  . TYR A 1 314 ? 100.960 70.893  103.117 1.00 169.24 ? 314 TYR A CG  1 
ATOM 2457 C CD1 . TYR A 1 314 ? 100.212 71.872  103.751 1.00 169.24 ? 314 TYR A CD1 1 
ATOM 2458 C CD2 . TYR A 1 314 ? 100.750 69.570  103.479 1.00 169.24 ? 314 TYR A CD2 1 
ATOM 2459 C CE1 . TYR A 1 314 ? 99.280  71.546  104.710 1.00 169.24 ? 314 TYR A CE1 1 
ATOM 2460 C CE2 . TYR A 1 314 ? 99.818  69.234  104.439 1.00 169.24 ? 314 TYR A CE2 1 
ATOM 2461 C CZ  . TYR A 1 314 ? 99.086  70.227  105.050 1.00 169.24 ? 314 TYR A CZ  1 
ATOM 2462 O OH  . TYR A 1 314 ? 98.156  69.902  106.007 1.00 169.24 ? 314 TYR A OH  1 
ATOM 2463 N N   . ALA A 1 315 ? 104.501 72.802  100.928 1.00 164.57 ? 315 ALA A N   1 
ATOM 2464 C CA  . ALA A 1 315 ? 105.391 72.987  99.786  1.00 164.57 ? 315 ALA A CA  1 
ATOM 2465 C C   . ALA A 1 315 ? 106.847 72.737  100.162 1.00 164.57 ? 315 ALA A C   1 
ATOM 2466 O O   . ALA A 1 315 ? 107.594 72.122  99.392  1.00 164.57 ? 315 ALA A O   1 
ATOM 2467 C CB  . ALA A 1 315 ? 105.219 74.393  99.211  1.00 164.57 ? 315 ALA A CB  1 
ATOM 2468 N N   . LYS A 1 316 ? 107.268 73.207  101.339 1.00 173.14 ? 316 LYS A N   1 
ATOM 2469 C CA  . LYS A 1 316 ? 108.654 73.025  101.758 1.00 173.14 ? 316 LYS A CA  1 
ATOM 2470 C C   . LYS A 1 316 ? 109.011 71.552  101.927 1.00 173.14 ? 316 LYS A C   1 
ATOM 2471 O O   . LYS A 1 316 ? 110.134 71.148  101.604 1.00 173.14 ? 316 LYS A O   1 
ATOM 2472 C CB  . LYS A 1 316 ? 108.911 73.786  103.059 1.00 173.14 ? 316 LYS A CB  1 
ATOM 2473 C CG  . LYS A 1 316 ? 110.361 73.770  103.514 1.00 173.14 ? 316 LYS A CG  1 
ATOM 2474 C CD  . LYS A 1 316 ? 110.549 74.566  104.795 1.00 173.14 ? 316 LYS A CD  1 
ATOM 2475 C CE  . LYS A 1 316 ? 110.119 76.012  104.612 1.00 173.14 ? 316 LYS A CE  1 
ATOM 2476 N NZ  . LYS A 1 316 ? 110.317 76.814  105.851 1.00 173.14 ? 316 LYS A NZ  1 
ATOM 2477 N N   . GLY A 1 317 ? 108.076 70.738  102.416 1.00 169.64 ? 317 GLY A N   1 
ATOM 2478 C CA  . GLY A 1 317 ? 108.353 69.336  102.669 1.00 169.64 ? 317 GLY A CA  1 
ATOM 2479 C C   . GLY A 1 317 ? 108.043 68.392  101.528 1.00 169.64 ? 317 GLY A C   1 
ATOM 2480 O O   . GLY A 1 317 ? 108.002 67.177  101.745 1.00 169.64 ? 317 GLY A O   1 
ATOM 2481 N N   . ALA A 1 318 ? 107.821 68.913  100.322 1.00 159.24 ? 318 ALA A N   1 
ATOM 2482 C CA  . ALA A 1 318 ? 107.498 68.086  99.170  1.00 159.24 ? 318 ALA A CA  1 
ATOM 2483 C C   . ALA A 1 318 ? 108.333 68.410  97.940  1.00 159.24 ? 318 ALA A C   1 
ATOM 2484 O O   . ALA A 1 318 ? 108.332 67.622  96.988  1.00 159.24 ? 318 ALA A O   1 
ATOM 2485 C CB  . ALA A 1 318 ? 106.010 68.212  98.820  1.00 159.24 ? 318 ALA A CB  1 
ATOM 2486 N N   . LEU A 1 319 ? 109.039 69.544  97.928  1.00 155.90 ? 319 LEU A N   1 
ATOM 2487 C CA  . LEU A 1 319 ? 109.842 69.914  96.769  1.00 155.90 ? 319 LEU A CA  1 
ATOM 2488 C C   . LEU A 1 319 ? 110.982 68.936  96.507  1.00 155.90 ? 319 LEU A C   1 
ATOM 2489 O O   . LEU A 1 319 ? 111.502 68.902  95.387  1.00 155.90 ? 319 LEU A O   1 
ATOM 2490 C CB  . LEU A 1 319 ? 110.388 71.334  96.939  1.00 155.90 ? 319 LEU A CB  1 
ATOM 2491 C CG  . LEU A 1 319 ? 110.769 71.805  98.345  1.00 155.90 ? 319 LEU A CG  1 
ATOM 2492 C CD1 . LEU A 1 319 ? 112.059 71.159  98.825  1.00 155.90 ? 319 LEU A CD1 1 
ATOM 2493 C CD2 . LEU A 1 319 ? 110.883 73.320  98.383  1.00 155.90 ? 319 LEU A CD2 1 
ATOM 2494 N N   . GLN A 1 320 ? 111.383 68.147  97.508  1.00 146.69 ? 320 GLN A N   1 
ATOM 2495 C CA  . GLN A 1 320 ? 112.412 67.136  97.285  1.00 146.69 ? 320 GLN A CA  1 
ATOM 2496 C C   . GLN A 1 320 ? 111.957 66.101  96.264  1.00 146.69 ? 320 GLN A C   1 
ATOM 2497 O O   . GLN A 1 320 ? 112.737 65.689  95.397  1.00 146.69 ? 320 GLN A O   1 
ATOM 2498 C CB  . GLN A 1 320 ? 112.788 66.465  98.607  1.00 146.69 ? 320 GLN A CB  1 
ATOM 2499 C CG  . GLN A 1 320 ? 111.600 66.057  99.464  1.00 146.69 ? 320 GLN A CG  1 
ATOM 2500 C CD  . GLN A 1 320 ? 112.016 65.455  100.793 1.00 146.69 ? 320 GLN A CD  1 
ATOM 2501 O OE1 . GLN A 1 320 ? 113.169 65.063  100.977 1.00 146.69 ? 320 GLN A OE1 1 
ATOM 2502 N NE2 . GLN A 1 320 ? 111.077 65.383  101.730 1.00 146.69 ? 320 GLN A NE2 1 
ATOM 2503 N N   . TYR A 1 321 ? 110.700 65.664  96.352  1.00 147.22 ? 321 TYR A N   1 
ATOM 2504 C CA  . TYR A 1 321 ? 110.134 64.725  95.393  1.00 147.22 ? 321 TYR A CA  1 
ATOM 2505 C C   . TYR A 1 321 ? 109.361 65.409  94.273  1.00 147.22 ? 321 TYR A C   1 
ATOM 2506 O O   . TYR A 1 321 ? 108.803 64.717  93.415  1.00 147.22 ? 321 TYR A O   1 
ATOM 2507 C CB  . TYR A 1 321 ? 109.209 63.728  96.105  1.00 147.22 ? 321 TYR A CB  1 
ATOM 2508 C CG  . TYR A 1 321 ? 109.756 63.187  97.408  1.00 147.22 ? 321 TYR A CG  1 
ATOM 2509 C CD1 . TYR A 1 321 ? 110.849 62.329  97.426  1.00 147.22 ? 321 TYR A CD1 1 
ATOM 2510 C CD2 . TYR A 1 321 ? 109.168 63.524  98.621  1.00 147.22 ? 321 TYR A CD2 1 
ATOM 2511 C CE1 . TYR A 1 321 ? 111.346 61.832  98.616  1.00 147.22 ? 321 TYR A CE1 1 
ATOM 2512 C CE2 . TYR A 1 321 ? 109.657 63.031  99.815  1.00 147.22 ? 321 TYR A CE2 1 
ATOM 2513 C CZ  . TYR A 1 321 ? 110.746 62.186  99.808  1.00 147.22 ? 321 TYR A CZ  1 
ATOM 2514 O OH  . TYR A 1 321 ? 111.235 61.693  100.997 1.00 147.22 ? 321 TYR A OH  1 
ATOM 2515 N N   . LEU A 1 322 ? 109.312 66.741  94.260  1.00 146.33 ? 322 LEU A N   1 
ATOM 2516 C CA  . LEU A 1 322 ? 108.555 67.469  93.250  1.00 146.33 ? 322 LEU A CA  1 
ATOM 2517 C C   . LEU A 1 322 ? 109.439 68.015  92.136  1.00 146.33 ? 322 LEU A C   1 
ATOM 2518 O O   . LEU A 1 322 ? 109.066 67.941  90.961  1.00 146.33 ? 322 LEU A O   1 
ATOM 2519 C CB  . LEU A 1 322 ? 107.780 68.618  93.902  1.00 146.33 ? 322 LEU A CB  1 
ATOM 2520 C CG  . LEU A 1 322 ? 106.265 68.442  94.013  1.00 146.33 ? 322 LEU A CG  1 
ATOM 2521 C CD1 . LEU A 1 322 ? 105.628 68.429  92.633  1.00 146.33 ? 322 LEU A CD1 1 
ATOM 2522 C CD2 . LEU A 1 322 ? 105.925 67.169  94.770  1.00 146.33 ? 322 LEU A CD2 1 
ATOM 2523 N N   . VAL A 1 323 ? 110.595 68.572  92.482  1.00 138.32 ? 323 VAL A N   1 
ATOM 2524 C CA  . VAL A 1 323 ? 111.494 69.183  91.505  1.00 138.32 ? 323 VAL A CA  1 
ATOM 2525 C C   . VAL A 1 323 ? 111.983 68.173  90.467  1.00 138.32 ? 323 VAL A C   1 
ATOM 2526 O O   . VAL A 1 323 ? 111.863 68.449  89.265  1.00 138.32 ? 323 VAL A O   1 
ATOM 2527 C CB  . VAL A 1 323 ? 112.681 69.870  92.201  1.00 138.32 ? 323 VAL A CB  1 
ATOM 2528 C CG1 . VAL A 1 323 ? 113.690 70.352  91.173  1.00 138.32 ? 323 VAL A CG1 1 
ATOM 2529 C CG2 . VAL A 1 323 ? 112.193 71.031  93.053  1.00 138.32 ? 323 VAL A CG2 1 
ATOM 2530 N N   . PRO A 1 324 ? 112.540 67.012  90.849  1.00 137.09 ? 324 PRO A N   1 
ATOM 2531 C CA  . PRO A 1 324 ? 113.094 66.117  89.817  1.00 137.09 ? 324 PRO A CA  1 
ATOM 2532 C C   . PRO A 1 324 ? 112.073 65.651  88.796  1.00 137.09 ? 324 PRO A C   1 
ATOM 2533 O O   . PRO A 1 324 ? 112.401 65.576  87.605  1.00 137.09 ? 324 PRO A O   1 
ATOM 2534 C CB  . PRO A 1 324 ? 113.653 64.941  90.631  1.00 137.09 ? 324 PRO A CB  1 
ATOM 2535 C CG  . PRO A 1 324 ? 112.897 64.969  91.904  1.00 137.09 ? 324 PRO A CG  1 
ATOM 2536 C CD  . PRO A 1 324 ? 112.680 66.421  92.194  1.00 137.09 ? 324 PRO A CD  1 
ATOM 2537 N N   . ILE A 1 325 ? 110.848 65.332  89.217  1.00 135.40 ? 325 ILE A N   1 
ATOM 2538 C CA  . ILE A 1 325 ? 109.828 64.931  88.255  1.00 135.40 ? 325 ILE A CA  1 
ATOM 2539 C C   . ILE A 1 325 ? 109.351 66.128  87.442  1.00 135.40 ? 325 ILE A C   1 
ATOM 2540 O O   . ILE A 1 325 ? 109.151 66.021  86.225  1.00 135.40 ? 325 ILE A O   1 
ATOM 2541 C CB  . ILE A 1 325 ? 108.663 64.222  88.970  1.00 135.40 ? 325 ILE A CB  1 
ATOM 2542 C CG1 . ILE A 1 325 ? 107.489 64.018  88.014  1.00 135.40 ? 325 ILE A CG1 1 
ATOM 2543 C CG2 . ILE A 1 325 ? 108.233 64.993  90.208  1.00 135.40 ? 325 ILE A CG2 1 
ATOM 2544 C CD1 . ILE A 1 325 ? 106.290 63.385  88.667  1.00 135.40 ? 325 ILE A CD1 1 
ATOM 2545 N N   . LEU A 1 326 ? 109.166 67.282  88.087  1.00 122.49 ? 326 LEU A N   1 
ATOM 2546 C CA  . LEU A 1 326 ? 108.688 68.464  87.377  1.00 122.49 ? 326 LEU A CA  1 
ATOM 2547 C C   . LEU A 1 326 ? 109.698 68.918  86.331  1.00 122.49 ? 326 LEU A C   1 
ATOM 2548 O O   . LEU A 1 326 ? 109.329 69.283  85.209  1.00 122.49 ? 326 LEU A O   1 
ATOM 2549 C CB  . LEU A 1 326 ? 108.398 69.587  88.372  1.00 122.49 ? 326 LEU A CB  1 
ATOM 2550 C CG  . LEU A 1 326 ? 107.744 70.849  87.815  1.00 122.49 ? 326 LEU A CG  1 
ATOM 2551 C CD1 . LEU A 1 326 ? 106.548 70.484  86.964  1.00 122.49 ? 326 LEU A CD1 1 
ATOM 2552 C CD2 . LEU A 1 326 ? 107.325 71.748  88.960  1.00 122.49 ? 326 LEU A CD2 1 
ATOM 2553 N N   . THR A 1 327 ? 110.982 68.909  86.688  1.00 130.44 ? 327 THR A N   1 
ATOM 2554 C CA  . THR A 1 327 ? 112.018 69.244  85.720  1.00 130.44 ? 327 THR A CA  1 
ATOM 2555 C C   . THR A 1 327 ? 112.075 68.229  84.586  1.00 130.44 ? 327 THR A C   1 
ATOM 2556 O O   . THR A 1 327 ? 112.305 68.607  83.431  1.00 130.44 ? 327 THR A O   1 
ATOM 2557 C CB  . THR A 1 327 ? 113.374 69.344  86.418  1.00 130.44 ? 327 THR A CB  1 
ATOM 2558 O OG1 . THR A 1 327 ? 113.596 68.166  87.203  1.00 130.44 ? 327 THR A OG1 1 
ATOM 2559 C CG2 . THR A 1 327 ? 113.418 70.572  87.322  1.00 130.44 ? 327 THR A CG2 1 
ATOM 2560 N N   . GLN A 1 328 ? 111.879 66.943  84.893  1.00 135.54 ? 328 GLN A N   1 
ATOM 2561 C CA  . GLN A 1 328 ? 111.908 65.922  83.851  1.00 135.54 ? 328 GLN A CA  1 
ATOM 2562 C C   . GLN A 1 328 ? 110.764 66.103  82.861  1.00 135.54 ? 328 GLN A C   1 
ATOM 2563 O O   . GLN A 1 328 ? 110.959 65.966  81.648  1.00 135.54 ? 328 GLN A O   1 
ATOM 2564 C CB  . GLN A 1 328 ? 111.856 64.528  84.477  1.00 135.54 ? 328 GLN A CB  1 
ATOM 2565 C CG  . GLN A 1 328 ? 112.136 63.408  83.493  1.00 135.54 ? 328 GLN A CG  1 
ATOM 2566 C CD  . GLN A 1 328 ? 113.542 63.473  82.934  1.00 135.54 ? 328 GLN A CD  1 
ATOM 2567 O OE1 . GLN A 1 328 ? 114.468 63.923  83.608  1.00 135.54 ? 328 GLN A OE1 1 
ATOM 2568 N NE2 . GLN A 1 328 ? 113.708 63.031  81.694  1.00 135.54 ? 328 GLN A NE2 1 
ATOM 2569 N N   . THR A 1 329 ? 109.566 66.419  83.355  1.00 124.84 ? 329 THR A N   1 
ATOM 2570 C CA  . THR A 1 329 ? 108.431 66.646  82.471  1.00 124.84 ? 329 THR A CA  1 
ATOM 2571 C C   . THR A 1 329 ? 108.427 68.048  81.881  1.00 124.84 ? 329 THR A C   1 
ATOM 2572 O O   . THR A 1 329 ? 107.586 68.343  81.025  1.00 124.84 ? 329 THR A O   1 
ATOM 2573 C CB  . THR A 1 329 ? 107.117 66.393  83.215  1.00 124.84 ? 329 THR A CB  1 
ATOM 2574 O OG1 . THR A 1 329 ? 106.027 66.413  82.285  1.00 124.84 ? 329 THR A OG1 1 
ATOM 2575 C CG2 . THR A 1 329 ? 106.885 67.461  84.271  1.00 124.84 ? 329 THR A CG2 1 
ATOM 2576 N N   . LEU A 1 330 ? 109.338 68.916  82.326  1.00 115.13 ? 330 LEU A N   1 
ATOM 2577 C CA  . LEU A 1 330 ? 109.504 70.225  81.708  1.00 115.13 ? 330 LEU A CA  1 
ATOM 2578 C C   . LEU A 1 330 ? 110.124 70.127  80.319  1.00 115.13 ? 330 LEU A C   1 
ATOM 2579 O O   . LEU A 1 330 ? 110.032 71.083  79.541  1.00 115.13 ? 330 LEU A O   1 
ATOM 2580 C CB  . LEU A 1 330 ? 110.362 71.116  82.610  1.00 115.13 ? 330 LEU A CB  1 
ATOM 2581 C CG  . LEU A 1 330 ? 110.497 72.599  82.254  1.00 115.13 ? 330 LEU A CG  1 
ATOM 2582 C CD1 . LEU A 1 330 ? 109.144 73.281  82.229  1.00 115.13 ? 330 LEU A CD1 1 
ATOM 2583 C CD2 . LEU A 1 330 ? 111.425 73.297  83.231  1.00 115.13 ? 330 LEU A CD2 1 
ATOM 2584 N N   . THR A 1 331 ? 110.740 68.992  79.987  1.00 125.91 ? 331 THR A N   1 
ATOM 2585 C CA  . THR A 1 331 ? 111.381 68.793  78.696  1.00 125.91 ? 331 THR A CA  1 
ATOM 2586 C C   . THR A 1 331 ? 110.505 68.014  77.723  1.00 125.91 ? 331 THR A C   1 
ATOM 2587 O O   . THR A 1 331 ? 111.031 67.367  76.809  1.00 125.91 ? 331 THR A O   1 
ATOM 2588 C CB  . THR A 1 331 ? 112.719 68.073  78.875  1.00 125.91 ? 331 THR A CB  1 
ATOM 2589 O OG1 . THR A 1 331 ? 112.484 66.693  79.180  1.00 125.91 ? 331 THR A OG1 1 
ATOM 2590 C CG2 . THR A 1 331 ? 113.513 68.700  80.008  1.00 125.91 ? 331 THR A CG2 1 
ATOM 2591 N N   . LYS A 1 332 ? 109.183 68.061  77.897  1.00 134.85 ? 332 LYS A N   1 
ATOM 2592 C CA  . LYS A 1 332 ? 108.244 67.359  77.030  1.00 134.85 ? 332 LYS A CA  1 
ATOM 2593 C C   . LYS A 1 332 ? 107.703 68.245  75.914  1.00 134.85 ? 332 LYS A C   1 
ATOM 2594 O O   . LYS A 1 332 ? 106.555 68.065  75.486  1.00 134.85 ? 332 LYS A O   1 
ATOM 2595 C CB  . LYS A 1 332 ? 107.095 66.784  77.860  1.00 134.85 ? 332 LYS A CB  1 
ATOM 2596 C CG  . LYS A 1 332 ? 107.536 65.859  78.984  1.00 134.85 ? 332 LYS A CG  1 
ATOM 2597 C CD  . LYS A 1 332 ? 108.292 64.649  78.458  1.00 134.85 ? 332 LYS A CD  1 
ATOM 2598 C CE  . LYS A 1 332 ? 108.691 63.714  79.590  1.00 134.85 ? 332 LYS A CE  1 
ATOM 2599 N NZ  . LYS A 1 332 ? 109.409 62.508  79.094  1.00 134.85 ? 332 LYS A NZ  1 
ATOM 2600 N N   . GLN A 1 333 ? 108.497 69.200  75.438  1.00 153.86 ? 333 GLN A N   1 
ATOM 2601 C CA  . GLN A 1 333 ? 108.063 70.117  74.397  1.00 153.86 ? 333 GLN A CA  1 
ATOM 2602 C C   . GLN A 1 333 ? 108.038 69.414  73.040  1.00 153.86 ? 333 GLN A C   1 
ATOM 2603 O O   . GLN A 1 333 ? 108.468 68.267  72.892  1.00 153.86 ? 333 GLN A O   1 
ATOM 2604 C CB  . GLN A 1 333 ? 108.974 71.343  74.360  1.00 153.86 ? 333 GLN A CB  1 
ATOM 2605 C CG  . GLN A 1 333 ? 108.245 72.661  74.155  1.00 153.86 ? 333 GLN A CG  1 
ATOM 2606 C CD  . GLN A 1 333 ? 109.106 73.859  74.507  1.00 153.86 ? 333 GLN A CD  1 
ATOM 2607 O OE1 . GLN A 1 333 ? 110.277 73.714  74.855  1.00 153.86 ? 333 GLN A OE1 1 
ATOM 2608 N NE2 . GLN A 1 333 ? 108.526 75.051  74.423  1.00 153.86 ? 333 GLN A NE2 1 
ATOM 2609 N N   . ASP A 1 334 ? 107.522 70.120  72.038  1.00 168.10 ? 334 ASP A N   1 
ATOM 2610 C CA  . ASP A 1 334 ? 107.346 69.574  70.701  1.00 168.10 ? 334 ASP A CA  1 
ATOM 2611 C C   . ASP A 1 334 ? 107.916 70.526  69.658  1.00 168.10 ? 334 ASP A C   1 
ATOM 2612 O O   . ASP A 1 334 ? 108.065 71.728  69.896  1.00 168.10 ? 334 ASP A O   1 
ATOM 2613 C CB  . ASP A 1 334 ? 105.867 69.303  70.405  1.00 168.10 ? 334 ASP A CB  1 
ATOM 2614 C CG  . ASP A 1 334 ? 105.009 70.540  70.561  1.00 168.10 ? 334 ASP A CG  1 
ATOM 2615 O OD1 . ASP A 1 334 ? 105.390 71.429  71.350  1.00 168.10 ? 334 ASP A OD1 1 
ATOM 2616 O OD2 . ASP A 1 334 ? 103.954 70.624  69.899  1.00 168.10 ? 334 ASP A OD2 1 
ATOM 2617 N N   . GLU A 1 335 ? 108.238 69.966  68.488  1.00 173.03 ? 335 GLU A N   1 
ATOM 2618 C CA  . GLU A 1 335 ? 108.775 70.776  67.398  1.00 173.03 ? 335 GLU A CA  1 
ATOM 2619 C C   . GLU A 1 335 ? 107.772 71.825  66.934  1.00 173.03 ? 335 GLU A C   1 
ATOM 2620 O O   . GLU A 1 335 ? 108.140 72.983  66.700  1.00 173.03 ? 335 GLU A O   1 
ATOM 2621 C CB  . GLU A 1 335 ? 109.187 69.879  66.230  1.00 173.03 ? 335 GLU A CB  1 
ATOM 2622 C CG  . GLU A 1 335 ? 110.504 69.148  66.431  1.00 173.03 ? 335 GLU A CG  1 
ATOM 2623 C CD  . GLU A 1 335 ? 111.709 70.034  66.177  1.00 173.03 ? 335 GLU A CD  1 
ATOM 2624 O OE1 . GLU A 1 335 ? 111.521 71.205  65.785  1.00 173.03 ? 335 GLU A OE1 1 
ATOM 2625 O OE2 . GLU A 1 335 ? 112.847 69.556  66.364  1.00 173.03 ? 335 GLU A OE2 1 
ATOM 2626 N N   . ASN A 1 336 ? 106.503 71.444  66.796  1.00 189.94 ? 336 ASN A N   1 
ATOM 2627 C CA  . ASN A 1 336 ? 105.455 72.376  66.378  1.00 189.94 ? 336 ASN A CA  1 
ATOM 2628 C C   . ASN A 1 336 ? 104.889 73.087  67.608  1.00 189.94 ? 336 ASN A C   1 
ATOM 2629 O O   . ASN A 1 336 ? 103.751 72.875  68.033  1.00 189.94 ? 336 ASN A O   1 
ATOM 2630 C CB  . ASN A 1 336 ? 104.371 71.644  65.598  1.00 189.94 ? 336 ASN A CB  1 
ATOM 2631 C CG  . ASN A 1 336 ? 103.340 72.586  65.008  1.00 189.94 ? 336 ASN A CG  1 
ATOM 2632 O OD1 . ASN A 1 336 ? 103.598 73.777  64.833  1.00 189.94 ? 336 ASN A OD1 1 
ATOM 2633 N ND2 . ASN A 1 336 ? 102.162 72.056  64.700  1.00 189.94 ? 336 ASN A ND2 1 
ATOM 2634 N N   . ASP A 1 337 ? 105.723 73.949  68.184  1.00 188.96 ? 337 ASP A N   1 
ATOM 2635 C CA  . ASP A 1 337 ? 105.336 74.679  69.384  1.00 188.96 ? 337 ASP A CA  1 
ATOM 2636 C C   . ASP A 1 337 ? 104.255 75.701  69.055  1.00 188.96 ? 337 ASP A C   1 
ATOM 2637 O O   . ASP A 1 337 ? 104.390 76.484  68.110  1.00 188.96 ? 337 ASP A O   1 
ATOM 2638 C CB  . ASP A 1 337 ? 106.556 75.369  69.995  1.00 188.96 ? 337 ASP A CB  1 
ATOM 2639 C CG  . ASP A 1 337 ? 106.342 75.767  71.446  1.00 188.96 ? 337 ASP A CG  1 
ATOM 2640 O OD1 . ASP A 1 337 ? 105.205 76.134  71.812  1.00 188.96 ? 337 ASP A OD1 1 
ATOM 2641 O OD2 . ASP A 1 337 ? 107.317 75.712  72.224  1.00 188.96 ? 337 ASP A OD2 1 
ATOM 2642 N N   . ASP A 1 338 ? 103.179 75.692  69.840  1.00 190.99 ? 338 ASP A N   1 
ATOM 2643 C CA  . ASP A 1 338 ? 102.079 76.629  69.676  1.00 190.99 ? 338 ASP A CA  1 
ATOM 2644 C C   . ASP A 1 338 ? 101.632 77.125  71.044  1.00 190.99 ? 338 ASP A C   1 
ATOM 2645 O O   . ASP A 1 338 ? 101.668 76.386  72.032  1.00 190.99 ? 338 ASP A O   1 
ATOM 2646 C CB  . ASP A 1 338 ? 100.899 75.981  68.934  1.00 190.99 ? 338 ASP A CB  1 
ATOM 2647 C CG  . ASP A 1 338 ? 99.969  77.002  68.305  1.00 190.99 ? 338 ASP A CG  1 
ATOM 2648 O OD1 . ASP A 1 338 ? 99.861  78.126  68.839  1.00 190.99 ? 338 ASP A OD1 1 
ATOM 2649 O OD2 . ASP A 1 338 ? 99.347  76.679  67.271  1.00 190.99 ? 338 ASP A OD2 1 
ATOM 2650 N N   . ASP A 1 339 ? 101.206 78.385  71.092  1.00 176.38 ? 339 ASP A N   1 
ATOM 2651 C CA  . ASP A 1 339 ? 100.763 79.011  72.330  1.00 176.38 ? 339 ASP A CA  1 
ATOM 2652 C C   . ASP A 1 339 ? 99.252  78.969  72.511  1.00 176.38 ? 339 ASP A C   1 
ATOM 2653 O O   . ASP A 1 339 ? 98.749  79.476  73.518  1.00 176.38 ? 339 ASP A O   1 
ATOM 2654 C CB  . ASP A 1 339 ? 101.243 80.465  72.389  1.00 176.38 ? 339 ASP A CB  1 
ATOM 2655 C CG  . ASP A 1 339 ? 102.743 80.590  72.223  1.00 176.38 ? 339 ASP A CG  1 
ATOM 2656 O OD1 . ASP A 1 339 ? 103.415 79.549  72.065  1.00 176.38 ? 339 ASP A OD1 1 
ATOM 2657 O OD2 . ASP A 1 339 ? 103.251 81.731  72.249  1.00 176.38 ? 339 ASP A OD2 1 
ATOM 2658 N N   . ASP A 1 340 ? 98.517  78.376  71.567  1.00 177.86 ? 340 ASP A N   1 
ATOM 2659 C CA  . ASP A 1 340 ? 97.060  78.386  71.638  1.00 177.86 ? 340 ASP A CA  1 
ATOM 2660 C C   . ASP A 1 340 ? 96.515  77.408  72.673  1.00 177.86 ? 340 ASP A C   1 
ATOM 2661 O O   . ASP A 1 340 ? 95.500  77.699  73.316  1.00 177.86 ? 340 ASP A O   1 
ATOM 2662 C CB  . ASP A 1 340 ? 96.465  78.075  70.264  1.00 177.86 ? 340 ASP A CB  1 
ATOM 2663 C CG  . ASP A 1 340 ? 96.921  76.735  69.716  1.00 177.86 ? 340 ASP A CG  1 
ATOM 2664 O OD1 . ASP A 1 340 ? 97.816  76.108  70.322  1.00 177.86 ? 340 ASP A OD1 1 
ATOM 2665 O OD2 . ASP A 1 340 ? 96.380  76.308  68.674  1.00 177.86 ? 340 ASP A OD2 1 
ATOM 2666 N N   . ASP A 1 341 ? 97.160  76.258  72.846  1.00 152.15 ? 341 ASP A N   1 
ATOM 2667 C CA  . ASP A 1 341 ? 96.656  75.189  73.698  1.00 152.15 ? 341 ASP A CA  1 
ATOM 2668 C C   . ASP A 1 341 ? 97.489  75.095  74.969  1.00 152.15 ? 341 ASP A C   1 
ATOM 2669 O O   . ASP A 1 341 ? 98.722  75.155  74.917  1.00 152.15 ? 341 ASP A O   1 
ATOM 2670 C CB  . ASP A 1 341 ? 96.676  73.849  72.958  1.00 152.15 ? 341 ASP A CB  1 
ATOM 2671 C CG  . ASP A 1 341 ? 95.995  72.739  73.738  1.00 152.15 ? 341 ASP A CG  1 
ATOM 2672 O OD1 . ASP A 1 341 ? 95.321  73.042  74.745  1.00 152.15 ? 341 ASP A OD1 1 
ATOM 2673 O OD2 . ASP A 1 341 ? 96.137  71.562  73.346  1.00 152.15 ? 341 ASP A OD2 1 
ATOM 2674 N N   . TRP A 1 342 ? 96.810  74.948  76.104  1.00 135.13 ? 342 TRP A N   1 
ATOM 2675 C CA  . TRP A 1 342 ? 97.495  74.712  77.367  1.00 135.13 ? 342 TRP A CA  1 
ATOM 2676 C C   . TRP A 1 342 ? 97.968  73.266  77.428  1.00 135.13 ? 342 TRP A C   1 
ATOM 2677 O O   . TRP A 1 342 ? 97.175  72.335  77.256  1.00 135.13 ? 342 TRP A O   1 
ATOM 2678 C CB  . TRP A 1 342 ? 96.563  75.024  78.538  1.00 135.13 ? 342 TRP A CB  1 
ATOM 2679 C CG  . TRP A 1 342 ? 97.199  74.897  79.892  1.00 135.13 ? 342 TRP A CG  1 
ATOM 2680 C CD1 . TRP A 1 342 ? 97.249  73.779  80.673  1.00 135.13 ? 342 TRP A CD1 1 
ATOM 2681 C CD2 . TRP A 1 342 ? 97.859  75.932  80.632  1.00 135.13 ? 342 TRP A CD2 1 
ATOM 2682 N NE1 . TRP A 1 342 ? 97.905  74.050  81.848  1.00 135.13 ? 342 TRP A NE1 1 
ATOM 2683 C CE2 . TRP A 1 342 ? 98.290  75.365  81.847  1.00 135.13 ? 342 TRP A CE2 1 
ATOM 2684 C CE3 . TRP A 1 342 ? 98.132  77.279  80.384  1.00 135.13 ? 342 TRP A CE3 1 
ATOM 2685 C CZ2 . TRP A 1 342 ? 98.978  76.099  82.811  1.00 135.13 ? 342 TRP A CZ2 1 
ATOM 2686 C CZ3 . TRP A 1 342 ? 98.815  78.007  81.342  1.00 135.13 ? 342 TRP A CZ3 1 
ATOM 2687 C CH2 . TRP A 1 342 ? 99.230  77.416  82.540  1.00 135.13 ? 342 TRP A CH2 1 
ATOM 2688 N N   . ASN A 1 343 ? 99.255  73.078  77.681  1.00 138.16 ? 343 ASN A N   1 
ATOM 2689 C CA  . ASN A 1 343 ? 99.906  71.781  77.634  1.00 138.16 ? 343 ASN A CA  1 
ATOM 2690 C C   . ASN A 1 343 ? 100.735 71.577  78.890  1.00 138.16 ? 343 ASN A C   1 
ATOM 2691 O O   . ASN A 1 343 ? 101.109 72.546  79.560  1.00 138.16 ? 343 ASN A O   1 
ATOM 2692 C CB  . ASN A 1 343 ? 100.801 71.662  76.391  1.00 138.16 ? 343 ASN A CB  1 
ATOM 2693 C CG  . ASN A 1 343 ? 100.006 71.625  75.104  1.00 138.16 ? 343 ASN A CG  1 
ATOM 2694 O OD1 . ASN A 1 343 ? 98.865  71.162  75.078  1.00 138.16 ? 343 ASN A OD1 1 
ATOM 2695 N ND2 . ASN A 1 343 ? 100.604 72.115  74.026  1.00 138.16 ? 343 ASN A ND2 1 
ATOM 2696 N N   . PRO A 1 344 ? 101.027 70.322  79.250  1.00 124.93 ? 344 PRO A N   1 
ATOM 2697 C CA  . PRO A 1 344 ? 101.837 70.078  80.454  1.00 124.93 ? 344 PRO A CA  1 
ATOM 2698 C C   . PRO A 1 344 ? 103.231 70.674  80.387  1.00 124.93 ? 344 PRO A C   1 
ATOM 2699 O O   . PRO A 1 344 ? 103.838 70.896  81.442  1.00 124.93 ? 344 PRO A O   1 
ATOM 2700 C CB  . PRO A 1 344 ? 101.889 68.546  80.543  1.00 124.93 ? 344 PRO A CB  1 
ATOM 2701 C CG  . PRO A 1 344 ? 101.529 68.061  79.170  1.00 124.93 ? 344 PRO A CG  1 
ATOM 2702 C CD  . PRO A 1 344 ? 100.560 69.066  78.639  1.00 124.93 ? 344 PRO A CD  1 
ATOM 2703 N N   . CYS A 1 345 ? 103.765 70.927  79.190  1.00 138.67 ? 345 CYS A N   1 
ATOM 2704 C CA  . CYS A 1 345 ? 105.070 71.574  79.090  1.00 138.67 ? 345 CYS A CA  1 
ATOM 2705 C C   . CYS A 1 345 ? 105.036 72.974  79.691  1.00 138.67 ? 345 CYS A C   1 
ATOM 2706 O O   . CYS A 1 345 ? 105.865 73.316  80.542  1.00 138.67 ? 345 CYS A O   1 
ATOM 2707 C CB  . CYS A 1 345 ? 105.525 71.627  77.633  1.00 138.67 ? 345 CYS A CB  1 
ATOM 2708 S SG  . CYS A 1 345 ? 104.447 72.586  76.545  1.00 138.67 ? 345 CYS A SG  1 
ATOM 2709 N N   . LYS A 1 346 ? 104.089 73.806  79.248  1.00 130.44 ? 346 LYS A N   1 
ATOM 2710 C CA  . LYS A 1 346 ? 103.941 75.134  79.835  1.00 130.44 ? 346 LYS A CA  1 
ATOM 2711 C C   . LYS A 1 346 ? 103.333 75.065  81.230  1.00 130.44 ? 346 LYS A C   1 
ATOM 2712 O O   . LYS A 1 346 ? 103.635 75.912  82.077  1.00 130.44 ? 346 LYS A O   1 
ATOM 2713 C CB  . LYS A 1 346 ? 103.103 76.032  78.924  1.00 130.44 ? 346 LYS A CB  1 
ATOM 2714 C CG  . LYS A 1 346 ? 101.768 75.444  78.501  1.00 130.44 ? 346 LYS A CG  1 
ATOM 2715 C CD  . LYS A 1 346 ? 101.053 76.354  77.515  1.00 130.44 ? 346 LYS A CD  1 
ATOM 2716 C CE  . LYS A 1 346 ? 101.903 76.599  76.285  1.00 130.44 ? 346 LYS A CE  1 
ATOM 2717 N NZ  . LYS A 1 346 ? 101.268 77.572  75.358  1.00 130.44 ? 346 LYS A NZ  1 
ATOM 2718 N N   . ALA A 1 347 ? 102.468 74.079  81.482  1.00 122.41 ? 347 ALA A N   1 
ATOM 2719 C CA  . ALA A 1 347 ? 101.929 73.898  82.825  1.00 122.41 ? 347 ALA A CA  1 
ATOM 2720 C C   . ALA A 1 347 ? 103.035 73.589  83.824  1.00 122.41 ? 347 ALA A C   1 
ATOM 2721 O O   . ALA A 1 347 ? 102.937 73.950  85.002  1.00 122.41 ? 347 ALA A O   1 
ATOM 2722 C CB  . ALA A 1 347 ? 100.884 72.784  82.828  1.00 122.41 ? 347 ALA A CB  1 
ATOM 2723 N N   . ALA A 1 348 ? 104.085 72.900  83.376  1.00 112.62 ? 348 ALA A N   1 
ATOM 2724 C CA  . ALA A 1 348 ? 105.203 72.606  84.263  1.00 112.62 ? 348 ALA A CA  1 
ATOM 2725 C C   . ALA A 1 348 ? 105.895 73.884  84.724  1.00 112.62 ? 348 ALA A C   1 
ATOM 2726 O O   . ALA A 1 348 ? 106.239 74.019  85.904  1.00 112.62 ? 348 ALA A O   1 
ATOM 2727 C CB  . ALA A 1 348 ? 106.194 71.675  83.567  1.00 112.62 ? 348 ALA A CB  1 
ATOM 2728 N N   . GLY A 1 349 ? 106.107 74.832  83.809  1.00 112.16 ? 349 GLY A N   1 
ATOM 2729 C CA  . GLY A 1 349 ? 106.823 76.046  84.172  1.00 112.16 ? 349 GLY A CA  1 
ATOM 2730 C C   . GLY A 1 349 ? 106.088 76.871  85.210  1.00 112.16 ? 349 GLY A C   1 
ATOM 2731 O O   . GLY A 1 349 ? 106.678 77.320  86.197  1.00 112.16 ? 349 GLY A O   1 
ATOM 2732 N N   . VAL A 1 350 ? 104.784 77.080  85.003  1.00 103.29 ? 350 VAL A N   1 
ATOM 2733 C CA  . VAL A 1 350 ? 104.028 77.940  85.909  1.00 103.29 ? 350 VAL A CA  1 
ATOM 2734 C C   . VAL A 1 350 ? 103.960 77.334  87.305  1.00 103.29 ? 350 VAL A C   1 
ATOM 2735 O O   . VAL A 1 350 ? 104.119 78.047  88.304  1.00 103.29 ? 350 VAL A O   1 
ATOM 2736 C CB  . VAL A 1 350 ? 102.622 78.231  85.346  1.00 103.29 ? 350 VAL A CB  1 
ATOM 2737 C CG1 . VAL A 1 350 ? 102.711 79.191  84.177  1.00 103.29 ? 350 VAL A CG1 1 
ATOM 2738 C CG2 . VAL A 1 350 ? 101.935 76.949  84.910  1.00 103.29 ? 350 VAL A CG2 1 
ATOM 2739 N N   . CYS A 1 351 ? 103.726 76.023  87.406  1.00 123.88 ? 351 CYS A N   1 
ATOM 2740 C CA  . CYS A 1 351 ? 103.733 75.377  88.714  1.00 123.88 ? 351 CYS A CA  1 
ATOM 2741 C C   . CYS A 1 351 ? 105.109 75.465  89.360  1.00 123.88 ? 351 CYS A C   1 
ATOM 2742 O O   . CYS A 1 351 ? 105.220 75.737  90.561  1.00 123.88 ? 351 CYS A O   1 
ATOM 2743 C CB  . CYS A 1 351 ? 103.287 73.921  88.586  1.00 123.88 ? 351 CYS A CB  1 
ATOM 2744 S SG  . CYS A 1 351 ? 103.097 73.058  90.159  1.00 123.88 ? 351 CYS A SG  1 
ATOM 2745 N N   . LEU A 1 352 ? 106.168 75.240  88.579  1.00 110.94 ? 352 LEU A N   1 
ATOM 2746 C CA  . LEU A 1 352 ? 107.523 75.416  89.093  1.00 110.94 ? 352 LEU A CA  1 
ATOM 2747 C C   . LEU A 1 352 ? 107.768 76.862  89.505  1.00 110.94 ? 352 LEU A C   1 
ATOM 2748 O O   . LEU A 1 352 ? 108.378 77.123  90.548  1.00 110.94 ? 352 LEU A O   1 
ATOM 2749 C CB  . LEU A 1 352 ? 108.541 74.979  88.041  1.00 110.94 ? 352 LEU A CB  1 
ATOM 2750 C CG  . LEU A 1 352 ? 110.025 75.094  88.394  1.00 110.94 ? 352 LEU A CG  1 
ATOM 2751 C CD1 . LEU A 1 352 ? 110.365 74.235  89.597  1.00 110.94 ? 352 LEU A CD1 1 
ATOM 2752 C CD2 . LEU A 1 352 ? 110.882 74.706  87.198  1.00 110.94 ? 352 LEU A CD2 1 
ATOM 2753 N N   . MET A 1 353 ? 107.304 77.813  88.691  1.00 116.61 ? 353 MET A N   1 
ATOM 2754 C CA  . MET A 1 353 ? 107.428 79.222  89.046  1.00 116.61 ? 353 MET A CA  1 
ATOM 2755 C C   . MET A 1 353 ? 106.645 79.538  90.314  1.00 116.61 ? 353 MET A C   1 
ATOM 2756 O O   . MET A 1 353 ? 107.131 80.267  91.188  1.00 116.61 ? 353 MET A O   1 
ATOM 2757 C CB  . MET A 1 353 ? 106.959 80.093  87.881  1.00 116.61 ? 353 MET A CB  1 
ATOM 2758 C CG  . MET A 1 353 ? 106.965 81.583  88.163  1.00 116.61 ? 353 MET A CG  1 
ATOM 2759 S SD  . MET A 1 353 ? 107.173 82.567  86.665  1.00 116.61 ? 353 MET A SD  1 
ATOM 2760 C CE  . MET A 1 353 ? 105.913 81.853  85.610  1.00 116.61 ? 353 MET A CE  1 
ATOM 2761 N N   . LEU A 1 354 ? 105.429 78.998  90.432  1.00 124.20 ? 354 LEU A N   1 
ATOM 2762 C CA  . LEU A 1 354 ? 104.647 79.192  91.648  1.00 124.20 ? 354 LEU A CA  1 
ATOM 2763 C C   . LEU A 1 354 ? 105.345 78.579  92.855  1.00 124.20 ? 354 LEU A C   1 
ATOM 2764 O O   . LEU A 1 354 ? 105.358 79.171  93.941  1.00 124.20 ? 354 LEU A O   1 
ATOM 2765 C CB  . LEU A 1 354 ? 103.251 78.597  91.478  1.00 124.20 ? 354 LEU A CB  1 
ATOM 2766 C CG  . LEU A 1 354 ? 102.114 79.589  91.224  1.00 124.20 ? 354 LEU A CG  1 
ATOM 2767 C CD1 . LEU A 1 354 ? 102.000 80.575  92.372  1.00 124.20 ? 354 LEU A CD1 1 
ATOM 2768 C CD2 . LEU A 1 354 ? 102.303 80.321  89.907  1.00 124.20 ? 354 LEU A CD2 1 
ATOM 2769 N N   . LEU A 1 355 ? 105.928 77.389  92.684  1.00 135.79 ? 355 LEU A N   1 
ATOM 2770 C CA  . LEU A 1 355 ? 106.638 76.744  93.784  1.00 135.79 ? 355 LEU A CA  1 
ATOM 2771 C C   . LEU A 1 355 ? 107.814 77.588  94.257  1.00 135.79 ? 355 LEU A C   1 
ATOM 2772 O O   . LEU A 1 355 ? 108.052 77.708  95.464  1.00 135.79 ? 355 LEU A O   1 
ATOM 2773 C CB  . LEU A 1 355 ? 107.116 75.355  93.361  1.00 135.79 ? 355 LEU A CB  1 
ATOM 2774 C CG  . LEU A 1 355 ? 106.068 74.243  93.288  1.00 135.79 ? 355 LEU A CG  1 
ATOM 2775 C CD1 . LEU A 1 355 ? 106.718 72.934  92.876  1.00 135.79 ? 355 LEU A CD1 1 
ATOM 2776 C CD2 . LEU A 1 355 ? 105.346 74.089  94.617  1.00 135.79 ? 355 LEU A CD2 1 
ATOM 2777 N N   . ALA A 1 356 ? 108.565 78.176  93.322  1.00 132.51 ? 356 ALA A N   1 
ATOM 2778 C CA  . ALA A 1 356 ? 109.706 78.999  93.706  1.00 132.51 ? 356 ALA A CA  1 
ATOM 2779 C C   . ALA A 1 356 ? 109.268 80.194  94.541  1.00 132.51 ? 356 ALA A C   1 
ATOM 2780 O O   . ALA A 1 356 ? 109.911 80.528  95.543  1.00 132.51 ? 356 ALA A O   1 
ATOM 2781 C CB  . ALA A 1 356 ? 110.463 79.463  92.462  1.00 132.51 ? 356 ALA A CB  1 
ATOM 2782 N N   . THR A 1 357 ? 108.176 80.850  94.143  1.00 133.81 ? 357 THR A N   1 
ATOM 2783 C CA  . THR A 1 357 ? 107.662 81.976  94.916  1.00 133.81 ? 357 THR A CA  1 
ATOM 2784 C C   . THR A 1 357 ? 107.190 81.533  96.294  1.00 133.81 ? 357 THR A C   1 
ATOM 2785 O O   . THR A 1 357 ? 107.414 82.233  97.288  1.00 133.81 ? 357 THR A O   1 
ATOM 2786 C CB  . THR A 1 357 ? 106.526 82.660  94.157  1.00 133.81 ? 357 THR A CB  1 
ATOM 2787 O OG1 . THR A 1 357 ? 105.491 81.707  93.881  1.00 133.81 ? 357 THR A OG1 1 
ATOM 2788 C CG2 . THR A 1 357 ? 107.038 83.243  92.850  1.00 133.81 ? 357 THR A CG2 1 
ATOM 2789 N N   . CYS A 1 358 ? 106.528 80.376  96.372  1.00 156.16 ? 358 CYS A N   1 
ATOM 2790 C CA  . CYS A 1 358 ? 105.968 79.919  97.640  1.00 156.16 ? 358 CYS A CA  1 
ATOM 2791 C C   . CYS A 1 358 ? 107.064 79.554  98.635  1.00 156.16 ? 358 CYS A C   1 
ATOM 2792 O O   . CYS A 1 358 ? 107.031 79.983  99.794  1.00 156.16 ? 358 CYS A O   1 
ATOM 2793 C CB  . CYS A 1 358 ? 105.039 78.729  97.401  1.00 156.16 ? 358 CYS A CB  1 
ATOM 2794 S SG  . CYS A 1 358 ? 104.329 78.020  98.904  1.00 156.16 ? 358 CYS A SG  1 
ATOM 2795 N N   . CYS A 1 359 ? 108.045 78.766  98.202  1.00 164.81 ? 359 CYS A N   1 
ATOM 2796 C CA  . CYS A 1 359 ? 109.115 78.313  99.080  1.00 164.81 ? 359 CYS A CA  1 
ATOM 2797 C C   . CYS A 1 359 ? 110.273 79.300  99.157  1.00 164.81 ? 359 CYS A C   1 
ATOM 2798 O O   . CYS A 1 359 ? 111.246 79.037  99.872  1.00 164.81 ? 359 CYS A O   1 
ATOM 2799 C CB  . CYS A 1 359 ? 109.633 76.946  98.625  1.00 164.81 ? 359 CYS A CB  1 
ATOM 2800 S SG  . CYS A 1 359 ? 110.715 77.008  97.183  1.00 164.81 ? 359 CYS A SG  1 
ATOM 2801 N N   . GLU A 1 360 ? 110.194 80.413  98.426  1.00 168.62 ? 360 GLU A N   1 
ATOM 2802 C CA  . GLU A 1 360 ? 111.180 81.487  98.487  1.00 168.62 ? 360 GLU A CA  1 
ATOM 2803 C C   . GLU A 1 360 ? 112.580 81.007  98.115  1.00 168.62 ? 360 GLU A C   1 
ATOM 2804 O O   . GLU A 1 360 ? 112.907 80.892  96.929  1.00 168.62 ? 360 GLU A O   1 
ATOM 2805 C CB  . GLU A 1 360 ? 111.183 82.123  99.882  1.00 168.62 ? 360 GLU A CB  1 
ATOM 2806 C CG  . GLU A 1 360 ? 111.930 83.444  99.972  1.00 168.62 ? 360 GLU A CG  1 
ATOM 2807 C CD  . GLU A 1 360 ? 111.850 84.069  101.351 1.00 168.62 ? 360 GLU A CD  1 
ATOM 2808 O OE1 . GLU A 1 360 ? 110.935 83.706  102.120 1.00 168.62 ? 360 GLU A OE1 1 
ATOM 2809 O OE2 . GLU A 1 360 ? 112.704 84.923  101.669 1.00 168.62 ? 360 GLU A OE2 1 
ATOM 2810 N N   . ASP A 1 361 ? 113.413 80.727  99.117  1.00 168.44 ? 361 ASP A N   1 
ATOM 2811 C CA  . ASP A 1 361 ? 114.830 80.463  98.908  1.00 168.44 ? 361 ASP A CA  1 
ATOM 2812 C C   . ASP A 1 361 ? 115.193 78.987  99.044  1.00 168.44 ? 361 ASP A C   1 
ATOM 2813 O O   . ASP A 1 361 ? 116.382 78.651  99.037  1.00 168.44 ? 361 ASP A O   1 
ATOM 2814 C CB  . ASP A 1 361 ? 115.664 81.298  99.884  1.00 168.44 ? 361 ASP A CB  1 
ATOM 2815 C CG  . ASP A 1 361 ? 117.070 81.557  99.379  1.00 168.44 ? 361 ASP A CG  1 
ATOM 2816 O OD1 . ASP A 1 361 ? 117.351 81.227  98.207  1.00 168.44 ? 361 ASP A OD1 1 
ATOM 2817 O OD2 . ASP A 1 361 ? 117.893 82.089  100.153 1.00 168.44 ? 361 ASP A OD2 1 
ATOM 2818 N N   . ASP A 1 362 ? 114.208 78.099  99.164  1.00 163.94 ? 362 ASP A N   1 
ATOM 2819 C CA  . ASP A 1 362 ? 114.466 76.669  99.333  1.00 163.94 ? 362 ASP A CA  1 
ATOM 2820 C C   . ASP A 1 362 ? 114.274 75.889  98.038  1.00 163.94 ? 362 ASP A C   1 
ATOM 2821 O O   . ASP A 1 362 ? 113.890 74.716  98.064  1.00 163.94 ? 362 ASP A O   1 
ATOM 2822 C CB  . ASP A 1 362 ? 113.583 76.097  100.438 1.00 163.94 ? 362 ASP A CB  1 
ATOM 2823 C CG  . ASP A 1 362 ? 114.094 76.436  101.825 1.00 163.94 ? 362 ASP A CG  1 
ATOM 2824 O OD1 . ASP A 1 362 ? 115.325 76.565  101.992 1.00 163.94 ? 362 ASP A OD1 1 
ATOM 2825 O OD2 . ASP A 1 362 ? 113.265 76.569  102.749 1.00 163.94 ? 362 ASP A OD2 1 
ATOM 2826 N N   . ILE A 1 363 ? 114.539 76.510  96.889  1.00 147.69 ? 363 ILE A N   1 
ATOM 2827 C CA  . ILE A 1 363 ? 114.416 75.831  95.604  1.00 147.69 ? 363 ILE A CA  1 
ATOM 2828 C C   . ILE A 1 363 ? 115.731 75.948  94.844  1.00 147.69 ? 363 ILE A C   1 
ATOM 2829 O O   . ILE A 1 363 ? 115.932 75.286  93.819  1.00 147.69 ? 363 ILE A O   1 
ATOM 2830 C CB  . ILE A 1 363 ? 113.248 76.406  94.781  1.00 147.69 ? 363 ILE A CB  1 
ATOM 2831 C CG1 . ILE A 1 363 ? 112.821 75.427  93.685  1.00 147.69 ? 363 ILE A CG1 1 
ATOM 2832 C CG2 . ILE A 1 363 ? 113.632 77.746  94.178  1.00 147.69 ? 363 ILE A CG2 1 
ATOM 2833 C CD1 . ILE A 1 363 ? 111.635 75.899  92.875  1.00 147.69 ? 363 ILE A CD1 1 
ATOM 2834 N N   . VAL A 1 364 ? 116.638 76.788  95.348  1.00 156.01 ? 364 VAL A N   1 
ATOM 2835 C CA  . VAL A 1 364 ? 117.909 77.011  94.655  1.00 156.01 ? 364 VAL A CA  1 
ATOM 2836 C C   . VAL A 1 364 ? 118.742 75.739  94.538  1.00 156.01 ? 364 VAL A C   1 
ATOM 2837 O O   . VAL A 1 364 ? 119.166 75.408  93.418  1.00 156.01 ? 364 VAL A O   1 
ATOM 2838 C CB  . VAL A 1 364 ? 118.681 78.163  95.327  1.00 156.01 ? 364 VAL A CB  1 
ATOM 2839 C CG1 . VAL A 1 364 ? 119.983 78.423  94.590  1.00 156.01 ? 364 VAL A CG1 1 
ATOM 2840 C CG2 . VAL A 1 364 ? 117.823 79.417  95.377  1.00 156.01 ? 364 VAL A CG2 1 
ATOM 2841 N N   . PRO A 1 365 ? 119.027 74.994  95.616  1.00 157.97 ? 365 PRO A N   1 
ATOM 2842 C CA  . PRO A 1 365 ? 119.875 73.800  95.467  1.00 157.97 ? 365 PRO A CA  1 
ATOM 2843 C C   . PRO A 1 365 ? 119.214 72.653  94.718  1.00 157.97 ? 365 PRO A C   1 
ATOM 2844 O O   . PRO A 1 365 ? 119.930 71.759  94.249  1.00 157.97 ? 365 PRO A O   1 
ATOM 2845 C CB  . PRO A 1 365 ? 120.181 73.405  96.916  1.00 157.97 ? 365 PRO A CB  1 
ATOM 2846 C CG  . PRO A 1 365 ? 119.009 73.890  97.677  1.00 157.97 ? 365 PRO A CG  1 
ATOM 2847 C CD  . PRO A 1 365 ? 118.612 75.181  97.020  1.00 157.97 ? 365 PRO A CD  1 
ATOM 2848 N N   . HIS A 1 366 ? 117.885 72.637  94.596  1.00 155.69 ? 366 HIS A N   1 
ATOM 2849 C CA  . HIS A 1 366 ? 117.219 71.501  93.969  1.00 155.69 ? 366 HIS A CA  1 
ATOM 2850 C C   . HIS A 1 366 ? 117.175 71.614  92.450  1.00 155.69 ? 366 HIS A C   1 
ATOM 2851 O O   . HIS A 1 366 ? 116.885 70.624  91.771  1.00 155.69 ? 366 HIS A O   1 
ATOM 2852 C CB  . HIS A 1 366 ? 115.798 71.352  94.518  1.00 155.69 ? 366 HIS A CB  1 
ATOM 2853 C CG  . HIS A 1 366 ? 115.738 71.156  96.001  1.00 155.69 ? 366 HIS A CG  1 
ATOM 2854 N ND1 . HIS A 1 366 ? 116.089 72.143  96.896  1.00 155.69 ? 366 HIS A ND1 1 
ATOM 2855 C CD2 . HIS A 1 366 ? 115.366 70.088  96.746  1.00 155.69 ? 366 HIS A CD2 1 
ATOM 2856 C CE1 . HIS A 1 366 ? 115.938 71.692  98.128  1.00 155.69 ? 366 HIS A CE1 1 
ATOM 2857 N NE2 . HIS A 1 366 ? 115.500 70.448  98.065  1.00 155.69 ? 366 HIS A NE2 1 
ATOM 2858 N N   . VAL A 1 367 ? 117.466 72.793  91.901  1.00 151.54 ? 367 VAL A N   1 
ATOM 2859 C CA  . VAL A 1 367 ? 117.364 73.027  90.463  1.00 151.54 ? 367 VAL A CA  1 
ATOM 2860 C C   . VAL A 1 367 ? 118.708 73.325  89.816  1.00 151.54 ? 367 VAL A C   1 
ATOM 2861 O O   . VAL A 1 367 ? 118.877 73.039  88.618  1.00 151.54 ? 367 VAL A O   1 
ATOM 2862 C CB  . VAL A 1 367 ? 116.364 74.163  90.149  1.00 151.54 ? 367 VAL A CB  1 
ATOM 2863 C CG1 . VAL A 1 367 ? 116.056 74.228  88.657  1.00 151.54 ? 367 VAL A CG1 1 
ATOM 2864 C CG2 . VAL A 1 367 ? 115.084 73.977  90.945  1.00 151.54 ? 367 VAL A CG2 1 
ATOM 2865 N N   . LEU A 1 368 ? 119.672 73.869  90.560  1.00 153.84 ? 368 LEU A N   1 
ATOM 2866 C CA  . LEU A 1 368 ? 120.967 74.196  89.965  1.00 153.84 ? 368 LEU A CA  1 
ATOM 2867 C C   . LEU A 1 368 ? 121.701 72.998  89.361  1.00 153.84 ? 368 LEU A C   1 
ATOM 2868 O O   . LEU A 1 368 ? 122.292 73.168  88.281  1.00 153.84 ? 368 LEU A O   1 
ATOM 2869 C CB  . LEU A 1 368 ? 121.845 74.936  90.988  1.00 153.84 ? 368 LEU A CB  1 
ATOM 2870 C CG  . LEU A 1 368 ? 122.282 74.376  92.344  1.00 153.84 ? 368 LEU A CG  1 
ATOM 2871 C CD1 . LEU A 1 368 ? 123.582 73.594  92.222  1.00 153.84 ? 368 LEU A CD1 1 
ATOM 2872 C CD2 . LEU A 1 368 ? 122.432 75.509  93.346  1.00 153.84 ? 368 LEU A CD2 1 
ATOM 2873 N N   . PRO A 1 369 ? 121.733 71.801  89.969  1.00 146.52 ? 369 PRO A N   1 
ATOM 2874 C CA  . PRO A 1 369 ? 122.445 70.696  89.305  1.00 146.52 ? 369 PRO A CA  1 
ATOM 2875 C C   . PRO A 1 369 ? 121.851 70.319  87.959  1.00 146.52 ? 369 PRO A C   1 
ATOM 2876 O O   . PRO A 1 369 ? 122.596 69.909  87.060  1.00 146.52 ? 369 PRO A O   1 
ATOM 2877 C CB  . PRO A 1 369 ? 122.333 69.546  90.314  1.00 146.52 ? 369 PRO A CB  1 
ATOM 2878 C CG  . PRO A 1 369 ? 121.099 69.842  91.068  1.00 146.52 ? 369 PRO A CG  1 
ATOM 2879 C CD  . PRO A 1 369 ? 121.076 71.333  91.205  1.00 146.52 ? 369 PRO A CD  1 
ATOM 2880 N N   . PHE A 1 370 ? 120.533 70.446  87.793  1.00 130.69 ? 370 PHE A N   1 
ATOM 2881 C CA  . PHE A 1 370 ? 119.899 70.071  86.533  1.00 130.69 ? 370 PHE A CA  1 
ATOM 2882 C C   . PHE A 1 370 ? 120.251 71.051  85.419  1.00 130.69 ? 370 PHE A C   1 
ATOM 2883 O O   . PHE A 1 370 ? 120.602 70.641  84.307  1.00 130.69 ? 370 PHE A O   1 
ATOM 2884 C CB  . PHE A 1 370 ? 118.384 69.987  86.722  1.00 130.69 ? 370 PHE A CB  1 
ATOM 2885 C CG  . PHE A 1 370 ? 117.608 69.958  85.435  1.00 130.69 ? 370 PHE A CG  1 
ATOM 2886 C CD1 . PHE A 1 370 ? 117.513 68.793  84.693  1.00 130.69 ? 370 PHE A CD1 1 
ATOM 2887 C CD2 . PHE A 1 370 ? 116.959 71.092  84.977  1.00 130.69 ? 370 PHE A CD2 1 
ATOM 2888 C CE1 . PHE A 1 370 ? 116.796 68.763  83.512  1.00 130.69 ? 370 PHE A CE1 1 
ATOM 2889 C CE2 . PHE A 1 370 ? 116.240 71.067  83.797  1.00 130.69 ? 370 PHE A CE2 1 
ATOM 2890 C CZ  . PHE A 1 370 ? 116.158 69.901  83.064  1.00 130.69 ? 370 PHE A CZ  1 
ATOM 2891 N N   . ILE A 1 371 ? 120.155 72.353  85.698  1.00 136.61 ? 371 ILE A N   1 
ATOM 2892 C CA  . ILE A 1 371 ? 120.402 73.352  84.662  1.00 136.61 ? 371 ILE A CA  1 
ATOM 2893 C C   . ILE A 1 371 ? 121.880 73.393  84.290  1.00 136.61 ? 371 ILE A C   1 
ATOM 2894 O O   . ILE A 1 371 ? 122.231 73.566  83.117  1.00 136.61 ? 371 ILE A O   1 
ATOM 2895 C CB  . ILE A 1 371 ? 119.880 74.732  85.107  1.00 136.61 ? 371 ILE A CB  1 
ATOM 2896 C CG1 . ILE A 1 371 ? 120.499 75.151  86.441  1.00 136.61 ? 371 ILE A CG1 1 
ATOM 2897 C CG2 . ILE A 1 371 ? 118.365 74.714  85.221  1.00 136.61 ? 371 ILE A CG2 1 
ATOM 2898 C CD1 . ILE A 1 371 ? 120.040 76.512  86.922  1.00 136.61 ? 371 ILE A CD1 1 
ATOM 2899 N N   . LYS A 1 372 ? 122.768 73.249  85.276  1.00 147.43 ? 372 LYS A N   1 
ATOM 2900 C CA  . LYS A 1 372 ? 124.200 73.313  84.999  1.00 147.43 ? 372 LYS A CA  1 
ATOM 2901 C C   . LYS A 1 372 ? 124.680 72.106  84.202  1.00 147.43 ? 372 LYS A C   1 
ATOM 2902 O O   . LYS A 1 372 ? 125.735 72.168  83.560  1.00 147.43 ? 372 LYS A O   1 
ATOM 2903 C CB  . LYS A 1 372 ? 124.980 73.427  86.309  1.00 147.43 ? 372 LYS A CB  1 
ATOM 2904 C CG  . LYS A 1 372 ? 126.421 73.881  86.147  1.00 147.43 ? 372 LYS A CG  1 
ATOM 2905 C CD  . LYS A 1 372 ? 126.623 75.268  86.733  1.00 147.43 ? 372 LYS A CD  1 
ATOM 2906 C CE  . LYS A 1 372 ? 126.355 75.273  88.230  1.00 147.43 ? 372 LYS A CE  1 
ATOM 2907 N NZ  . LYS A 1 372 ? 126.546 76.623  88.827  1.00 147.43 ? 372 LYS A NZ  1 
ATOM 2908 N N   . GLU A 1 373 ? 123.926 71.008  84.223  1.00 149.37 ? 373 GLU A N   1 
ATOM 2909 C CA  . GLU A 1 373 ? 124.346 69.781  83.558  1.00 149.37 ? 373 GLU A CA  1 
ATOM 2910 C C   . GLU A 1 373 ? 123.770 69.635  82.155  1.00 149.37 ? 373 GLU A C   1 
ATOM 2911 O O   . GLU A 1 373 ? 124.434 69.068  81.278  1.00 149.37 ? 373 GLU A O   1 
ATOM 2912 C CB  . GLU A 1 373 ? 123.955 68.571  84.413  1.00 149.37 ? 373 GLU A CB  1 
ATOM 2913 C CG  . GLU A 1 373 ? 124.270 67.222  83.793  1.00 149.37 ? 373 GLU A CG  1 
ATOM 2914 C CD  . GLU A 1 373 ? 123.049 66.570  83.179  1.00 149.37 ? 373 GLU A CD  1 
ATOM 2915 O OE1 . GLU A 1 373 ? 121.927 67.058  83.427  1.00 149.37 ? 373 GLU A OE1 1 
ATOM 2916 O OE2 . GLU A 1 373 ? 123.211 65.567  82.453  1.00 149.37 ? 373 GLU A OE2 1 
ATOM 2917 N N   . HIS A 1 374 ? 122.563 70.146  81.914  1.00 141.90 ? 374 HIS A N   1 
ATOM 2918 C CA  . HIS A 1 374 ? 121.905 70.019  80.620  1.00 141.90 ? 374 HIS A CA  1 
ATOM 2919 C C   . HIS A 1 374 ? 121.965 71.306  79.803  1.00 141.90 ? 374 HIS A C   1 
ATOM 2920 O O   . HIS A 1 374 ? 121.240 71.441  78.812  1.00 141.90 ? 374 HIS A O   1 
ATOM 2921 C CB  . HIS A 1 374 ? 120.452 69.577  80.803  1.00 141.90 ? 374 HIS A CB  1 
ATOM 2922 C CG  . HIS A 1 374 ? 120.285 68.098  80.962  1.00 141.90 ? 374 HIS A CG  1 
ATOM 2923 N ND1 . HIS A 1 374 ? 119.386 67.541  81.844  1.00 141.90 ? 374 HIS A ND1 1 
ATOM 2924 C CD2 . HIS A 1 374 ? 120.895 67.060  80.342  1.00 141.90 ? 374 HIS A CD2 1 
ATOM 2925 C CE1 . HIS A 1 374 ? 119.453 66.224  81.767  1.00 141.90 ? 374 HIS A CE1 1 
ATOM 2926 N NE2 . HIS A 1 374 ? 120.361 65.906  80.862  1.00 141.90 ? 374 HIS A NE2 1 
ATOM 2927 N N   . ILE A 1 375 ? 122.818 72.257  80.196  1.00 149.27 ? 375 ILE A N   1 
ATOM 2928 C CA  . ILE A 1 375 ? 122.966 73.492  79.428  1.00 149.27 ? 375 ILE A CA  1 
ATOM 2929 C C   . ILE A 1 375 ? 123.890 73.322  78.233  1.00 149.27 ? 375 ILE A C   1 
ATOM 2930 O O   . ILE A 1 375 ? 123.974 74.226  77.392  1.00 149.27 ? 375 ILE A O   1 
ATOM 2931 C CB  . ILE A 1 375 ? 123.475 74.629  80.336  1.00 149.27 ? 375 ILE A CB  1 
ATOM 2932 C CG1 . ILE A 1 375 ? 123.060 75.996  79.783  1.00 149.27 ? 375 ILE A CG1 1 
ATOM 2933 C CG2 . ILE A 1 375 ? 124.986 74.551  80.506  1.00 149.27 ? 375 ILE A CG2 1 
ATOM 2934 C CD1 . ILE A 1 375 ? 123.480 77.158  80.657  1.00 149.27 ? 375 ILE A CD1 1 
ATOM 2935 N N   . LYS A 1 376 ? 124.575 72.183  78.126  1.00 153.55 ? 376 LYS A N   1 
ATOM 2936 C CA  . LYS A 1 376 ? 125.489 71.902  77.026  1.00 153.55 ? 376 LYS A CA  1 
ATOM 2937 C C   . LYS A 1 376 ? 125.040 70.680  76.231  1.00 153.55 ? 376 LYS A C   1 
ATOM 2938 O O   . LYS A 1 376 ? 125.828 70.083  75.495  1.00 153.55 ? 376 LYS A O   1 
ATOM 2939 C CB  . LYS A 1 376 ? 126.912 71.709  77.547  1.00 153.55 ? 376 LYS A CB  1 
ATOM 2940 C CG  . LYS A 1 376 ? 127.063 70.532  78.497  1.00 153.55 ? 376 LYS A CG  1 
ATOM 2941 C CD  . LYS A 1 376 ? 128.435 70.515  79.150  1.00 153.55 ? 376 LYS A CD  1 
ATOM 2942 C CE  . LYS A 1 376 ? 128.634 71.723  80.054  1.00 153.55 ? 376 LYS A CE  1 
ATOM 2943 N NZ  . LYS A 1 376 ? 127.621 71.780  81.146  1.00 153.55 ? 376 LYS A NZ  1 
ATOM 2944 N N   . ASN A 1 377 ? 123.775 70.297  76.381  1.00 148.50 ? 377 ASN A N   1 
ATOM 2945 C CA  . ASN A 1 377 ? 123.268 69.114  75.705  1.00 148.50 ? 377 ASN A CA  1 
ATOM 2946 C C   . ASN A 1 377 ? 123.248 69.334  74.194  1.00 148.50 ? 377 ASN A C   1 
ATOM 2947 O O   . ASN A 1 377 ? 122.835 70.400  73.727  1.00 148.50 ? 377 ASN A O   1 
ATOM 2948 C CB  . ASN A 1 377 ? 121.864 68.778  76.202  1.00 148.50 ? 377 ASN A CB  1 
ATOM 2949 C CG  . ASN A 1 377 ? 121.398 67.410  75.749  1.00 148.50 ? 377 ASN A CG  1 
ATOM 2950 O OD1 . ASN A 1 377 ? 120.875 67.253  74.646  1.00 148.50 ? 377 ASN A OD1 1 
ATOM 2951 N ND2 . ASN A 1 377 ? 121.586 66.410  76.601  1.00 148.50 ? 377 ASN A ND2 1 
ATOM 2952 N N   . PRO A 1 378 ? 123.698 68.354  73.405  1.00 156.44 ? 378 PRO A N   1 
ATOM 2953 C CA  . PRO A 1 378 ? 123.647 68.512  71.942  1.00 156.44 ? 378 PRO A CA  1 
ATOM 2954 C C   . PRO A 1 378 ? 122.242 68.720  71.411  1.00 156.44 ? 378 PRO A C   1 
ATOM 2955 O O   . PRO A 1 378 ? 122.062 69.437  70.418  1.00 156.44 ? 378 PRO A O   1 
ATOM 2956 C CB  . PRO A 1 378 ? 124.256 67.201  71.424  1.00 156.44 ? 378 PRO A CB  1 
ATOM 2957 C CG  . PRO A 1 378 ? 125.049 66.663  72.572  1.00 156.44 ? 378 PRO A CG  1 
ATOM 2958 C CD  . PRO A 1 378 ? 124.299 67.070  73.802  1.00 156.44 ? 378 PRO A CD  1 
ATOM 2959 N N   . ASP A 1 379 ? 121.240 68.115  72.040  1.00 150.95 ? 379 ASP A N   1 
ATOM 2960 C CA  . ASP A 1 379 ? 119.858 68.277  71.621  1.00 150.95 ? 379 ASP A CA  1 
ATOM 2961 C C   . ASP A 1 379 ? 119.228 69.463  72.339  1.00 150.95 ? 379 ASP A C   1 
ATOM 2962 O O   . ASP A 1 379 ? 119.448 69.683  73.533  1.00 150.95 ? 379 ASP A O   1 
ATOM 2963 C CB  . ASP A 1 379 ? 119.054 67.005  71.901  1.00 150.95 ? 379 ASP A CB  1 
ATOM 2964 C CG  . ASP A 1 379 ? 117.699 67.010  71.221  1.00 150.95 ? 379 ASP A CG  1 
ATOM 2965 O OD1 . ASP A 1 379 ? 117.427 67.940  70.433  1.00 150.95 ? 379 ASP A OD1 1 
ATOM 2966 O OD2 . ASP A 1 379 ? 116.902 66.082  71.476  1.00 150.95 ? 379 ASP A OD2 1 
ATOM 2967 N N   . TRP A 1 380 ? 118.431 70.228  71.590  1.00 136.91 ? 380 TRP A N   1 
ATOM 2968 C CA  . TRP A 1 380 ? 117.819 71.443  72.116  1.00 136.91 ? 380 TRP A CA  1 
ATOM 2969 C C   . TRP A 1 380 ? 116.807 71.176  73.223  1.00 136.91 ? 380 TRP A C   1 
ATOM 2970 O O   . TRP A 1 380 ? 116.479 72.102  73.971  1.00 136.91 ? 380 TRP A O   1 
ATOM 2971 C CB  . TRP A 1 380 ? 117.149 72.226  70.983  1.00 136.91 ? 380 TRP A CB  1 
ATOM 2972 C CG  . TRP A 1 380 ? 116.107 71.453  70.239  1.00 136.91 ? 380 TRP A CG  1 
ATOM 2973 C CD1 . TRP A 1 380 ? 116.312 70.576  69.215  1.00 136.91 ? 380 TRP A CD1 1 
ATOM 2974 C CD2 . TRP A 1 380 ? 114.691 71.497  70.451  1.00 136.91 ? 380 TRP A CD2 1 
ATOM 2975 N NE1 . TRP A 1 380 ? 115.114 70.065  68.782  1.00 136.91 ? 380 TRP A NE1 1 
ATOM 2976 C CE2 . TRP A 1 380 ? 114.103 70.616  69.524  1.00 136.91 ? 380 TRP A CE2 1 
ATOM 2977 C CE3 . TRP A 1 380 ? 113.864 72.193  71.339  1.00 136.91 ? 380 TRP A CE3 1 
ATOM 2978 C CZ2 . TRP A 1 380 ? 112.727 70.412  69.459  1.00 136.91 ? 380 TRP A CZ2 1 
ATOM 2979 C CZ3 . TRP A 1 380 ? 112.498 71.989  71.270  1.00 136.91 ? 380 TRP A CZ3 1 
ATOM 2980 C CH2 . TRP A 1 380 ? 111.944 71.107  70.338  1.00 136.91 ? 380 TRP A CH2 1 
ATOM 2981 N N   . ARG A 1 381 ? 116.298 69.946  73.336  1.00 143.56 ? 381 ARG A N   1 
ATOM 2982 C CA  . ARG A 1 381 ? 115.292 69.646  74.352  1.00 143.56 ? 381 ARG A CA  1 
ATOM 2983 C C   . ARG A 1 381 ? 115.810 69.935  75.757  1.00 143.56 ? 381 ARG A C   1 
ATOM 2984 O O   . ARG A 1 381 ? 115.154 70.632  76.540  1.00 143.56 ? 381 ARG A O   1 
ATOM 2985 C CB  . ARG A 1 381 ? 114.847 68.188  74.235  1.00 143.56 ? 381 ARG A CB  1 
ATOM 2986 C CG  . ARG A 1 381 ? 114.045 67.877  72.981  1.00 143.56 ? 381 ARG A CG  1 
ATOM 2987 C CD  . ARG A 1 381 ? 112.678 68.548  73.003  1.00 143.56 ? 381 ARG A CD  1 
ATOM 2988 N NE  . ARG A 1 381 ? 111.887 68.208  71.825  1.00 143.56 ? 381 ARG A NE  1 
ATOM 2989 C CZ  . ARG A 1 381 ? 111.120 67.131  71.722  1.00 143.56 ? 381 ARG A CZ  1 
ATOM 2990 N NH1 . ARG A 1 381 ? 111.025 66.253  72.707  1.00 143.56 ? 381 ARG A NH1 1 
ATOM 2991 N NH2 . ARG A 1 381 ? 110.430 66.930  70.602  1.00 143.56 ? 381 ARG A NH2 1 
ATOM 2992 N N   . TYR A 1 382 ? 116.989 69.408  76.097  1.00 140.80 ? 382 TYR A N   1 
ATOM 2993 C CA  . TYR A 1 382 ? 117.523 69.595  77.442  1.00 140.80 ? 382 TYR A CA  1 
ATOM 2994 C C   . TYR A 1 382 ? 118.109 70.985  77.643  1.00 140.80 ? 382 TYR A C   1 
ATOM 2995 O O   . TYR A 1 382 ? 118.107 71.495  78.769  1.00 140.80 ? 382 TYR A O   1 
ATOM 2996 C CB  . TYR A 1 382 ? 118.576 68.528  77.743  1.00 140.80 ? 382 TYR A CB  1 
ATOM 2997 C CG  . TYR A 1 382 ? 118.010 67.129  77.801  1.00 140.80 ? 382 TYR A CG  1 
ATOM 2998 C CD1 . TYR A 1 382 ? 117.508 66.613  78.987  1.00 140.80 ? 382 TYR A CD1 1 
ATOM 2999 C CD2 . TYR A 1 382 ? 117.972 66.327  76.668  1.00 140.80 ? 382 TYR A CD2 1 
ATOM 3000 C CE1 . TYR A 1 382 ? 116.987 65.336  79.045  1.00 140.80 ? 382 TYR A CE1 1 
ATOM 3001 C CE2 . TYR A 1 382 ? 117.453 65.050  76.715  1.00 140.80 ? 382 TYR A CE2 1 
ATOM 3002 C CZ  . TYR A 1 382 ? 116.961 64.559  77.907  1.00 140.80 ? 382 TYR A CZ  1 
ATOM 3003 O OH  . TYR A 1 382 ? 116.442 63.287  77.963  1.00 140.80 ? 382 TYR A OH  1 
ATOM 3004 N N   . ARG A 1 383 ? 118.619 71.608  76.579  1.00 131.70 ? 383 ARG A N   1 
ATOM 3005 C CA  . ARG A 1 383 ? 119.106 72.978  76.697  1.00 131.70 ? 383 ARG A CA  1 
ATOM 3006 C C   . ARG A 1 383 ? 117.951 73.958  76.860  1.00 131.70 ? 383 ARG A C   1 
ATOM 3007 O O   . ARG A 1 383 ? 118.105 75.005  77.500  1.00 131.70 ? 383 ARG A O   1 
ATOM 3008 C CB  . ARG A 1 383 ? 119.964 73.343  75.485  1.00 131.70 ? 383 ARG A CB  1 
ATOM 3009 C CG  . ARG A 1 383 ? 121.399 72.836  75.568  1.00 131.70 ? 383 ARG A CG  1 
ATOM 3010 C CD  . ARG A 1 383 ? 122.273 73.417  74.461  1.00 131.70 ? 383 ARG A CD  1 
ATOM 3011 N NE  . ARG A 1 383 ? 121.993 72.824  73.157  1.00 131.70 ? 383 ARG A NE  1 
ATOM 3012 C CZ  . ARG A 1 383 ? 121.185 73.352  72.248  1.00 131.70 ? 383 ARG A CZ  1 
ATOM 3013 N NH1 . ARG A 1 383 ? 120.553 74.494  72.464  1.00 131.70 ? 383 ARG A NH1 1 
ATOM 3014 N NH2 . ARG A 1 383 ? 121.006 72.717  71.092  1.00 131.70 ? 383 ARG A NH2 1 
ATOM 3015 N N   . ASP A 1 384 ? 116.789 73.637  76.284  1.00 124.42 ? 384 ASP A N   1 
ATOM 3016 C CA  . ASP A 1 384 ? 115.621 74.500  76.433  1.00 124.42 ? 384 ASP A CA  1 
ATOM 3017 C C   . ASP A 1 384 ? 115.215 74.638  77.893  1.00 124.42 ? 384 ASP A C   1 
ATOM 3018 O O   . ASP A 1 384 ? 114.994 75.752  78.381  1.00 124.42 ? 384 ASP A O   1 
ATOM 3019 C CB  . ASP A 1 384 ? 114.459 73.950  75.606  1.00 124.42 ? 384 ASP A CB  1 
ATOM 3020 C CG  . ASP A 1 384 ? 113.110 74.375  76.144  1.00 124.42 ? 384 ASP A CG  1 
ATOM 3021 O OD1 . ASP A 1 384 ? 112.761 75.565  76.005  1.00 124.42 ? 384 ASP A OD1 1 
ATOM 3022 O OD2 . ASP A 1 384 ? 112.398 73.516  76.706  1.00 124.42 ? 384 ASP A OD2 1 
ATOM 3023 N N   . ALA A 1 385 ? 115.119 73.517  78.611  1.00 109.18 ? 385 ALA A N   1 
ATOM 3024 C CA  . ALA A 1 385 ? 114.700 73.578  80.006  1.00 109.18 ? 385 ALA A CA  1 
ATOM 3025 C C   . ALA A 1 385 ? 115.841 74.023  80.911  1.00 109.18 ? 385 ALA A C   1 
ATOM 3026 O O   . ALA A 1 385 ? 115.604 74.480  82.035  1.00 109.18 ? 385 ALA A O   1 
ATOM 3027 C CB  . ALA A 1 385 ? 114.160 72.221  80.453  1.00 109.18 ? 385 ALA A CB  1 
ATOM 3028 N N   . ALA A 1 386 ? 117.083 73.903  80.443  1.00 116.31 ? 386 ALA A N   1 
ATOM 3029 C CA  . ALA A 1 386 ? 118.213 74.342  81.254  1.00 116.31 ? 386 ALA A CA  1 
ATOM 3030 C C   . ALA A 1 386 ? 118.222 75.858  81.396  1.00 116.31 ? 386 ALA A C   1 
ATOM 3031 O O   . ALA A 1 386 ? 118.690 76.397  82.405  1.00 116.31 ? 386 ALA A O   1 
ATOM 3032 C CB  . ALA A 1 386 ? 119.524 73.846  80.648  1.00 116.31 ? 386 ALA A CB  1 
ATOM 3033 N N   . VAL A 1 387 ? 117.704 76.564  80.389  1.00 110.99 ? 387 VAL A N   1 
ATOM 3034 C CA  . VAL A 1 387 ? 117.645 78.018  80.463  1.00 110.99 ? 387 VAL A CA  1 
ATOM 3035 C C   . VAL A 1 387 ? 116.255 78.479  80.887  1.00 110.99 ? 387 VAL A C   1 
ATOM 3036 O O   . VAL A 1 387 ? 116.116 79.492  81.585  1.00 110.99 ? 387 VAL A O   1 
ATOM 3037 C CB  . VAL A 1 387 ? 118.079 78.635  79.116  1.00 110.99 ? 387 VAL A CB  1 
ATOM 3038 C CG1 . VAL A 1 387 ? 117.147 78.208  77.991  1.00 110.99 ? 387 VAL A CG1 1 
ATOM 3039 C CG2 . VAL A 1 387 ? 118.164 80.152  79.215  1.00 110.99 ? 387 VAL A CG2 1 
ATOM 3040 N N   . MET A 1 388 ? 115.209 77.747  80.492  1.00 109.53 ? 388 MET A N   1 
ATOM 3041 C CA  . MET A 1 388 ? 113.852 78.119  80.880  1.00 109.53 ? 388 MET A CA  1 
ATOM 3042 C C   . MET A 1 388 ? 113.657 78.020  82.387  1.00 109.53 ? 388 MET A C   1 
ATOM 3043 O O   . MET A 1 388 ? 113.056 78.909  82.999  1.00 109.53 ? 388 MET A O   1 
ATOM 3044 C CB  . MET A 1 388 ? 112.836 77.239  80.149  1.00 109.53 ? 388 MET A CB  1 
ATOM 3045 C CG  . MET A 1 388 ? 111.401 77.739  80.232  1.00 109.53 ? 388 MET A CG  1 
ATOM 3046 S SD  . MET A 1 388 ? 110.244 76.686  79.334  1.00 109.53 ? 388 MET A SD  1 
ATOM 3047 C CE  . MET A 1 388 ? 108.708 77.565  79.606  1.00 109.53 ? 388 MET A CE  1 
ATOM 3048 N N   . ALA A 1 389 ? 114.157 76.947  83.005  1.00 119.71 ? 389 ALA A N   1 
ATOM 3049 C CA  . ALA A 1 389 ? 114.016 76.805  84.451  1.00 119.71 ? 389 ALA A CA  1 
ATOM 3050 C C   . ALA A 1 389 ? 114.873 77.824  85.190  1.00 119.71 ? 389 ALA A C   1 
ATOM 3051 O O   . ALA A 1 389 ? 114.570 78.189  86.332  1.00 119.71 ? 389 ALA A O   1 
ATOM 3052 C CB  . ALA A 1 389 ? 114.376 75.384  84.880  1.00 119.71 ? 389 ALA A CB  1 
ATOM 3053 N N   . PHE A 1 390 ? 115.951 78.289  84.556  1.00 130.48 ? 390 PHE A N   1 
ATOM 3054 C CA  . PHE A 1 390 ? 116.787 79.317  85.165  1.00 130.48 ? 390 PHE A CA  1 
ATOM 3055 C C   . PHE A 1 390 ? 116.010 80.613  85.362  1.00 130.48 ? 390 PHE A C   1 
ATOM 3056 O O   . PHE A 1 390 ? 116.126 81.264  86.407  1.00 130.48 ? 390 PHE A O   1 
ATOM 3057 C CB  . PHE A 1 390 ? 118.029 79.549  84.302  1.00 130.48 ? 390 PHE A CB  1 
ATOM 3058 C CG  . PHE A 1 390 ? 118.900 80.679  84.774  1.00 130.48 ? 390 PHE A CG  1 
ATOM 3059 C CD1 . PHE A 1 390 ? 119.739 80.518  85.863  1.00 130.48 ? 390 PHE A CD1 1 
ATOM 3060 C CD2 . PHE A 1 390 ? 118.892 81.896  84.115  1.00 130.48 ? 390 PHE A CD2 1 
ATOM 3061 C CE1 . PHE A 1 390 ? 120.543 81.556  86.295  1.00 130.48 ? 390 PHE A CE1 1 
ATOM 3062 C CE2 . PHE A 1 390 ? 119.693 82.936  84.541  1.00 130.48 ? 390 PHE A CE2 1 
ATOM 3063 C CZ  . PHE A 1 390 ? 120.520 82.766  85.632  1.00 130.48 ? 390 PHE A CZ  1 
ATOM 3064 N N   . GLY A 1 391 ? 115.214 81.007  84.366  1.00 126.69 ? 391 GLY A N   1 
ATOM 3065 C CA  . GLY A 1 391 ? 114.422 82.218  84.501  1.00 126.69 ? 391 GLY A CA  1 
ATOM 3066 C C   . GLY A 1 391 ? 113.209 82.032  85.393  1.00 126.69 ? 391 GLY A C   1 
ATOM 3067 O O   . GLY A 1 391 ? 112.770 82.972  86.063  1.00 126.69 ? 391 GLY A O   1 
ATOM 3068 N N   . CYS A 1 392 ? 112.642 80.824  85.407  1.00 119.09 ? 392 CYS A N   1 
ATOM 3069 C CA  . CYS A 1 392 ? 111.456 80.557  86.211  1.00 119.09 ? 392 CYS A CA  1 
ATOM 3070 C C   . CYS A 1 392 ? 111.737 80.549  87.707  1.00 119.09 ? 392 CYS A C   1 
ATOM 3071 O O   . CYS A 1 392 ? 110.791 80.612  88.497  1.00 119.09 ? 392 CYS A O   1 
ATOM 3072 C CB  . CYS A 1 392 ? 110.832 79.220  85.805  1.00 119.09 ? 392 CYS A CB  1 
ATOM 3073 S SG  . CYS A 1 392 ? 110.107 79.215  84.149  1.00 119.09 ? 392 CYS A SG  1 
ATOM 3074 N N   . ILE A 1 393 ? 113.003 80.470  88.115  1.00 128.63 ? 393 ILE A N   1 
ATOM 3075 C CA  . ILE A 1 393 ? 113.359 80.485  89.528  1.00 128.63 ? 393 ILE A CA  1 
ATOM 3076 C C   . ILE A 1 393 ? 114.009 81.802  89.938  1.00 128.63 ? 393 ILE A C   1 
ATOM 3077 O O   . ILE A 1 393 ? 114.469 81.932  91.076  1.00 128.63 ? 393 ILE A O   1 
ATOM 3078 C CB  . ILE A 1 393 ? 114.263 79.295  89.885  1.00 128.63 ? 393 ILE A CB  1 
ATOM 3079 C CG1 . ILE A 1 393 ? 115.600 79.403  89.151  1.00 128.63 ? 393 ILE A CG1 1 
ATOM 3080 C CG2 . ILE A 1 393 ? 113.567 77.986  89.549  1.00 128.63 ? 393 ILE A CG2 1 
ATOM 3081 C CD1 . ILE A 1 393 ? 116.551 78.281  89.472  1.00 128.63 ? 393 ILE A CD1 1 
ATOM 3082 N N   . LEU A 1 394 ? 114.068 82.779  89.031  1.00 127.53 ? 394 LEU A N   1 
ATOM 3083 C CA  . LEU A 1 394 ? 114.684 84.063  89.346  1.00 127.53 ? 394 LEU A CA  1 
ATOM 3084 C C   . LEU A 1 394 ? 113.914 84.850  90.399  1.00 127.53 ? 394 LEU A C   1 
ATOM 3085 O O   . LEU A 1 394 ? 114.508 85.704  91.067  1.00 127.53 ? 394 LEU A O   1 
ATOM 3086 C CB  . LEU A 1 394 ? 114.823 84.908  88.076  1.00 127.53 ? 394 LEU A CB  1 
ATOM 3087 C CG  . LEU A 1 394 ? 115.962 84.549  87.119  1.00 127.53 ? 394 LEU A CG  1 
ATOM 3088 C CD1 . LEU A 1 394 ? 115.900 85.411  85.873  1.00 127.53 ? 394 LEU A CD1 1 
ATOM 3089 C CD2 . LEU A 1 394 ? 117.308 84.708  87.802  1.00 127.53 ? 394 LEU A CD2 1 
ATOM 3090 N N   . GLU A 1 395 ? 112.619 84.590  90.567  1.00 124.39 ? 395 GLU A N   1 
ATOM 3091 C CA  . GLU A 1 395 ? 111.797 85.339  91.508  1.00 124.39 ? 395 GLU A CA  1 
ATOM 3092 C C   . GLU A 1 395 ? 111.562 84.534  92.780  1.00 124.39 ? 395 GLU A C   1 
ATOM 3093 O O   . GLU A 1 395 ? 111.219 83.348  92.728  1.00 124.39 ? 395 GLU A O   1 
ATOM 3094 C CB  . GLU A 1 395 ? 110.457 85.740  90.879  1.00 124.39 ? 395 GLU A CB  1 
ATOM 3095 C CG  . GLU A 1 395 ? 109.611 84.596  90.336  1.00 124.39 ? 395 GLU A CG  1 
ATOM 3096 C CD  . GLU A 1 395 ? 108.355 85.092  89.635  1.00 124.39 ? 395 GLU A CD  1 
ATOM 3097 O OE1 . GLU A 1 395 ? 108.388 86.207  89.072  1.00 124.39 ? 395 GLU A OE1 1 
ATOM 3098 O OE2 . GLU A 1 395 ? 107.333 84.373  89.652  1.00 124.39 ? 395 GLU A OE2 1 
ATOM 3099 N N   . GLY A 1 396 ? 111.763 85.190  93.922  1.00 143.94 ? 396 GLY A N   1 
ATOM 3100 C CA  . GLY A 1 396 ? 111.570 84.585  95.220  1.00 143.94 ? 396 GLY A CA  1 
ATOM 3101 C C   . GLY A 1 396 ? 112.824 84.552  96.077  1.00 143.94 ? 396 GLY A C   1 
ATOM 3102 O O   . GLY A 1 396 ? 112.797 84.935  97.251  1.00 143.94 ? 396 GLY A O   1 
ATOM 3103 N N   . PRO A 1 397 ? 113.948 84.102  95.519  1.00 150.56 ? 397 PRO A N   1 
ATOM 3104 C CA  . PRO A 1 397 ? 115.227 84.267  96.218  1.00 150.56 ? 397 PRO A CA  1 
ATOM 3105 C C   . PRO A 1 397 ? 115.686 85.716  96.201  1.00 150.56 ? 397 PRO A C   1 
ATOM 3106 O O   . PRO A 1 397 ? 115.359 86.494  95.302  1.00 150.56 ? 397 PRO A O   1 
ATOM 3107 C CB  . PRO A 1 397 ? 116.187 83.372  95.426  1.00 150.56 ? 397 PRO A CB  1 
ATOM 3108 C CG  . PRO A 1 397 ? 115.306 82.369  94.772  1.00 150.56 ? 397 PRO A CG  1 
ATOM 3109 C CD  . PRO A 1 397 ? 114.052 83.112  94.434  1.00 150.56 ? 397 PRO A CD  1 
ATOM 3110 N N   . GLU A 1 398 ? 116.458 86.072  97.221  1.00 184.96 ? 398 GLU A N   1 
ATOM 3111 C CA  . GLU A 1 398 ? 116.991 87.423  97.302  1.00 184.96 ? 398 GLU A CA  1 
ATOM 3112 C C   . GLU A 1 398 ? 118.082 87.618  96.249  1.00 184.96 ? 398 GLU A C   1 
ATOM 3113 O O   . GLU A 1 398 ? 118.845 86.690  95.964  1.00 184.96 ? 398 GLU A O   1 
ATOM 3114 C CB  . GLU A 1 398 ? 117.529 87.702  98.707  1.00 184.96 ? 398 GLU A CB  1 
ATOM 3115 C CG  . GLU A 1 398 ? 119.002 88.064  98.786  1.00 184.96 ? 398 GLU A CG  1 
ATOM 3116 C CD  . GLU A 1 398 ? 119.891 86.851  98.981  1.00 184.96 ? 398 GLU A CD  1 
ATOM 3117 O OE1 . GLU A 1 398 ? 119.405 85.718  98.787  1.00 184.96 ? 398 GLU A OE1 1 
ATOM 3118 O OE2 . GLU A 1 398 ? 121.075 87.031  99.336  1.00 184.96 ? 398 GLU A OE2 1 
ATOM 3119 N N   . PRO A 1 399 ? 118.164 88.806  95.638  1.00 187.22 ? 399 PRO A N   1 
ATOM 3120 C CA  . PRO A 1 399 ? 119.092 88.995  94.509  1.00 187.22 ? 399 PRO A CA  1 
ATOM 3121 C C   . PRO A 1 399 ? 120.559 88.779  94.846  1.00 187.22 ? 399 PRO A C   1 
ATOM 3122 O O   . PRO A 1 399 ? 121.301 88.296  93.982  1.00 187.22 ? 399 PRO A O   1 
ATOM 3123 C CB  . PRO A 1 399 ? 118.836 90.448  94.085  1.00 187.22 ? 399 PRO A CB  1 
ATOM 3124 C CG  . PRO A 1 399 ? 117.459 90.748  94.575  1.00 187.22 ? 399 PRO A CG  1 
ATOM 3125 C CD  . PRO A 1 399 ? 117.320 89.991  95.863  1.00 187.22 ? 399 PRO A CD  1 
ATOM 3126 N N   . SER A 1 400 ? 121.004 89.126  96.058  1.00 190.04 ? 400 SER A N   1 
ATOM 3127 C CA  . SER A 1 400 ? 122.436 89.125  96.347  1.00 190.04 ? 400 SER A CA  1 
ATOM 3128 C C   . SER A 1 400 ? 123.035 87.726  96.245  1.00 190.04 ? 400 SER A C   1 
ATOM 3129 O O   . SER A 1 400 ? 124.111 87.550  95.661  1.00 190.04 ? 400 SER A O   1 
ATOM 3130 C CB  . SER A 1 400 ? 122.693 89.720  97.732  1.00 190.04 ? 400 SER A CB  1 
ATOM 3131 O OG  . SER A 1 400 ? 122.129 88.916  98.752  1.00 190.04 ? 400 SER A OG  1 
ATOM 3132 N N   . GLN A 1 401 ? 122.360 86.718  96.800  1.00 182.53 ? 401 GLN A N   1 
ATOM 3133 C CA  . GLN A 1 401 ? 122.885 85.359  96.735  1.00 182.53 ? 401 GLN A CA  1 
ATOM 3134 C C   . GLN A 1 401 ? 122.689 84.724  95.365  1.00 182.53 ? 401 GLN A C   1 
ATOM 3135 O O   . GLN A 1 401 ? 123.366 83.739  95.049  1.00 182.53 ? 401 GLN A O   1 
ATOM 3136 C CB  . GLN A 1 401 ? 122.237 84.488  97.815  1.00 182.53 ? 401 GLN A CB  1 
ATOM 3137 C CG  . GLN A 1 401 ? 123.042 83.253  98.185  1.00 182.53 ? 401 GLN A CG  1 
ATOM 3138 C CD  . GLN A 1 401 ? 122.587 82.628  99.490  1.00 182.53 ? 401 GLN A CD  1 
ATOM 3139 O OE1 . GLN A 1 401 ? 121.654 83.111  100.132 1.00 182.53 ? 401 GLN A OE1 1 
ATOM 3140 N NE2 . GLN A 1 401 ? 123.250 81.550  99.891  1.00 182.53 ? 401 GLN A NE2 1 
ATOM 3141 N N   . LEU A 1 402 ? 121.787 85.263  94.549  1.00 179.78 ? 402 LEU A N   1 
ATOM 3142 C CA  . LEU A 1 402 ? 121.587 84.796  93.184  1.00 179.78 ? 402 LEU A CA  1 
ATOM 3143 C C   . LEU A 1 402 ? 122.507 85.495  92.190  1.00 179.78 ? 402 LEU A C   1 
ATOM 3144 O O   . LEU A 1 402 ? 122.542 85.107  91.018  1.00 179.78 ? 402 LEU A O   1 
ATOM 3145 C CB  . LEU A 1 402 ? 120.121 84.995  92.776  1.00 179.78 ? 402 LEU A CB  1 
ATOM 3146 C CG  . LEU A 1 402 ? 119.572 84.196  91.593  1.00 179.78 ? 402 LEU A CG  1 
ATOM 3147 C CD1 . LEU A 1 402 ? 119.802 82.707  91.789  1.00 179.78 ? 402 LEU A CD1 1 
ATOM 3148 C CD2 . LEU A 1 402 ? 118.091 84.485  91.404  1.00 179.78 ? 402 LEU A CD2 1 
ATOM 3149 N N   . LYS A 1 403 ? 123.252 86.509  92.634  1.00 181.03 ? 403 LYS A N   1 
ATOM 3150 C CA  . LYS A 1 403 ? 124.198 87.190  91.751  1.00 181.03 ? 403 LYS A CA  1 
ATOM 3151 C C   . LYS A 1 403 ? 125.286 86.273  91.201  1.00 181.03 ? 403 LYS A C   1 
ATOM 3152 O O   . LYS A 1 403 ? 125.553 86.337  89.989  1.00 181.03 ? 403 LYS A O   1 
ATOM 3153 C CB  . LYS A 1 403 ? 124.810 88.393  92.479  1.00 181.03 ? 403 LYS A CB  1 
ATOM 3154 C CG  . LYS A 1 403 ? 123.874 89.583  92.615  1.00 181.03 ? 403 LYS A CG  1 
ATOM 3155 C CD  . LYS A 1 403 ? 124.570 90.766  93.269  1.00 181.03 ? 403 LYS A CD  1 
ATOM 3156 C CE  . LYS A 1 403 ? 123.642 91.966  93.369  1.00 181.03 ? 403 LYS A CE  1 
ATOM 3157 N NZ  . LYS A 1 403 ? 124.315 93.143  93.987  1.00 181.03 ? 403 LYS A NZ  1 
ATOM 3158 N N   . PRO A 1 404 ? 125.959 85.432  91.999  1.00 176.84 ? 404 PRO A N   1 
ATOM 3159 C CA  . PRO A 1 404 ? 127.036 84.607  91.422  1.00 176.84 ? 404 PRO A CA  1 
ATOM 3160 C C   . PRO A 1 404 ? 126.574 83.688  90.305  1.00 176.84 ? 404 PRO A C   1 
ATOM 3161 O O   . PRO A 1 404 ? 127.349 83.430  89.375  1.00 176.84 ? 404 PRO A O   1 
ATOM 3162 C CB  . PRO A 1 404 ? 127.557 83.811  92.628  1.00 176.84 ? 404 PRO A CB  1 
ATOM 3163 C CG  . PRO A 1 404 ? 126.453 83.857  93.627  1.00 176.84 ? 404 PRO A CG  1 
ATOM 3164 C CD  . PRO A 1 404 ? 125.835 85.203  93.450  1.00 176.84 ? 404 PRO A CD  1 
ATOM 3165 N N   . LEU A 1 405 ? 125.341 83.182  90.362  1.00 169.76 ? 405 LEU A N   1 
ATOM 3166 C CA  . LEU A 1 405 ? 124.870 82.289  89.308  1.00 169.76 ? 405 LEU A CA  1 
ATOM 3167 C C   . LEU A 1 405 ? 124.559 83.053  88.027  1.00 169.76 ? 405 LEU A C   1 
ATOM 3168 O O   . LEU A 1 405 ? 124.904 82.600  86.929  1.00 169.76 ? 405 LEU A O   1 
ATOM 3169 C CB  . LEU A 1 405 ? 123.639 81.519  89.783  1.00 169.76 ? 405 LEU A CB  1 
ATOM 3170 C CG  . LEU A 1 405 ? 123.029 80.537  88.782  1.00 169.76 ? 405 LEU A CG  1 
ATOM 3171 C CD1 . LEU A 1 405 ? 124.056 79.501  88.351  1.00 169.76 ? 405 LEU A CD1 1 
ATOM 3172 C CD2 . LEU A 1 405 ? 121.802 79.864  89.375  1.00 169.76 ? 405 LEU A CD2 1 
ATOM 3173 N N   . VAL A 1 406 ? 123.904 84.211  88.144  1.00 157.35 ? 406 VAL A N   1 
ATOM 3174 C CA  . VAL A 1 406 ? 123.493 84.950  86.953  1.00 157.35 ? 406 VAL A CA  1 
ATOM 3175 C C   . VAL A 1 406 ? 124.693 85.563  86.237  1.00 157.35 ? 406 VAL A C   1 
ATOM 3176 O O   . VAL A 1 406 ? 124.708 85.640  85.002  1.00 157.35 ? 406 VAL A O   1 
ATOM 3177 C CB  . VAL A 1 406 ? 122.437 86.013  87.316  1.00 157.35 ? 406 VAL A CB  1 
ATOM 3178 C CG1 . VAL A 1 406 ? 121.230 85.354  87.967  1.00 157.35 ? 406 VAL A CG1 1 
ATOM 3179 C CG2 . VAL A 1 406 ? 123.017 87.080  88.230  1.00 157.35 ? 406 VAL A CG2 1 
ATOM 3180 N N   . ILE A 1 407 ? 125.706 86.016  86.980  1.00 161.56 ? 407 ILE A N   1 
ATOM 3181 C CA  . ILE A 1 407 ? 126.842 86.682  86.350  1.00 161.56 ? 407 ILE A CA  1 
ATOM 3182 C C   . ILE A 1 407 ? 127.655 85.737  85.471  1.00 161.56 ? 407 ILE A C   1 
ATOM 3183 O O   . ILE A 1 407 ? 128.068 86.131  84.373  1.00 161.56 ? 407 ILE A O   1 
ATOM 3184 C CB  . ILE A 1 407 ? 127.738 87.358  87.406  1.00 161.56 ? 407 ILE A CB  1 
ATOM 3185 C CG1 . ILE A 1 407 ? 128.853 88.159  86.730  1.00 161.56 ? 407 ILE A CG1 1 
ATOM 3186 C CG2 . ILE A 1 407 ? 128.322 86.343  88.381  1.00 161.56 ? 407 ILE A CG2 1 
ATOM 3187 C CD1 . ILE A 1 407 ? 128.347 89.296  85.874  1.00 161.56 ? 407 ILE A CD1 1 
ATOM 3188 N N   . GLN A 1 408 ? 127.893 84.502  85.912  1.00 158.05 ? 408 GLN A N   1 
ATOM 3189 C CA  . GLN A 1 408 ? 128.655 83.541  85.126  1.00 158.05 ? 408 GLN A CA  1 
ATOM 3190 C C   . GLN A 1 408 ? 127.856 82.948  83.973  1.00 158.05 ? 408 GLN A C   1 
ATOM 3191 O O   . GLN A 1 408 ? 128.451 82.568  82.959  1.00 158.05 ? 408 GLN A O   1 
ATOM 3192 C CB  . GLN A 1 408 ? 129.179 82.416  86.028  1.00 158.05 ? 408 GLN A CB  1 
ATOM 3193 C CG  . GLN A 1 408 ? 128.101 81.550  86.664  1.00 158.05 ? 408 GLN A CG  1 
ATOM 3194 C CD  . GLN A 1 408 ? 127.812 80.293  85.865  1.00 158.05 ? 408 GLN A CD  1 
ATOM 3195 O OE1 . GLN A 1 408 ? 128.498 79.993  84.887  1.00 158.05 ? 408 GLN A OE1 1 
ATOM 3196 N NE2 . GLN A 1 408 ? 126.794 79.549  86.281  1.00 158.05 ? 408 GLN A NE2 1 
ATOM 3197 N N   . ALA A 1 409 ? 126.533 82.853  84.104  1.00 149.21 ? 409 ALA A N   1 
ATOM 3198 C CA  . ALA A 1 409 ? 125.683 82.340  83.040  1.00 149.21 ? 409 ALA A CA  1 
ATOM 3199 C C   . ALA A 1 409 ? 125.384 83.372  81.962  1.00 149.21 ? 409 ALA A C   1 
ATOM 3200 O O   . ALA A 1 409 ? 124.933 82.994  80.875  1.00 149.21 ? 409 ALA A O   1 
ATOM 3201 C CB  . ALA A 1 409 ? 124.364 81.816  83.619  1.00 149.21 ? 409 ALA A CB  1 
ATOM 3202 N N   . MET A 1 410 ? 125.615 84.656  82.235  1.00 150.87 ? 410 MET A N   1 
ATOM 3203 C CA  . MET A 1 410 ? 125.359 85.683  81.229  1.00 150.87 ? 410 MET A CA  1 
ATOM 3204 C C   . MET A 1 410 ? 126.190 85.507  79.962  1.00 150.87 ? 410 MET A C   1 
ATOM 3205 O O   . MET A 1 410 ? 125.620 85.650  78.866  1.00 150.87 ? 410 MET A O   1 
ATOM 3206 C CB  . MET A 1 410 ? 125.573 87.075  81.841  1.00 150.87 ? 410 MET A CB  1 
ATOM 3207 C CG  . MET A 1 410 ? 125.239 88.221  80.902  1.00 150.87 ? 410 MET A CG  1 
ATOM 3208 S SD  . MET A 1 410 ? 123.527 88.173  80.338  1.00 150.87 ? 410 MET A SD  1 
ATOM 3209 C CE  . MET A 1 410 ? 122.655 88.295  81.897  1.00 150.87 ? 410 MET A CE  1 
ATOM 3210 N N   . PRO A 1 411 ? 127.501 85.225  80.016  1.00 149.99 ? 411 PRO A N   1 
ATOM 3211 C CA  . PRO A 1 411 ? 128.224 84.961  78.758  1.00 149.99 ? 411 PRO A CA  1 
ATOM 3212 C C   . PRO A 1 411 ? 127.658 83.792  77.973  1.00 149.99 ? 411 PRO A C   1 
ATOM 3213 O O   . PRO A 1 411 ? 127.753 83.775  76.740  1.00 149.99 ? 411 PRO A O   1 
ATOM 3214 C CB  . PRO A 1 411 ? 129.658 84.689  79.231  1.00 149.99 ? 411 PRO A CB  1 
ATOM 3215 C CG  . PRO A 1 411 ? 129.771 85.419  80.513  1.00 149.99 ? 411 PRO A CG  1 
ATOM 3216 C CD  . PRO A 1 411 ? 128.426 85.291  81.163  1.00 149.99 ? 411 PRO A CD  1 
ATOM 3217 N N   . THR A 1 412 ? 127.088 82.797  78.654  1.00 143.58 ? 412 THR A N   1 
ATOM 3218 C CA  . THR A 1 412 ? 126.444 81.702  77.940  1.00 143.58 ? 412 THR A CA  1 
ATOM 3219 C C   . THR A 1 412 ? 125.126 82.138  77.312  1.00 143.58 ? 412 THR A C   1 
ATOM 3220 O O   . THR A 1 412 ? 124.768 81.653  76.233  1.00 143.58 ? 412 THR A O   1 
ATOM 3221 C CB  . THR A 1 412 ? 126.216 80.517  78.878  1.00 143.58 ? 412 THR A CB  1 
ATOM 3222 O OG1 . THR A 1 412 ? 125.348 80.911  79.948  1.00 143.58 ? 412 THR A OG1 1 
ATOM 3223 C CG2 . THR A 1 412 ? 127.541 80.033  79.451  1.00 143.58 ? 412 THR A CG2 1 
ATOM 3224 N N   . LEU A 1 413 ? 124.396 83.046  77.967  1.00 137.15 ? 413 LEU A N   1 
ATOM 3225 C CA  . LEU A 1 413 ? 123.091 83.459  77.459  1.00 137.15 ? 413 LEU A CA  1 
ATOM 3226 C C   . LEU A 1 413 ? 123.204 84.134  76.098  1.00 137.15 ? 413 LEU A C   1 
ATOM 3227 O O   . LEU A 1 413 ? 122.418 83.843  75.190  1.00 137.15 ? 413 LEU A O   1 
ATOM 3228 C CB  . LEU A 1 413 ? 122.408 84.390  78.461  1.00 137.15 ? 413 LEU A CB  1 
ATOM 3229 C CG  . LEU A 1 413 ? 121.948 83.765  79.779  1.00 137.15 ? 413 LEU A CG  1 
ATOM 3230 C CD1 . LEU A 1 413 ? 121.297 84.812  80.667  1.00 137.15 ? 413 LEU A CD1 1 
ATOM 3231 C CD2 . LEU A 1 413 ? 120.994 82.610  79.520  1.00 137.15 ? 413 LEU A CD2 1 
ATOM 3232 N N   . ILE A 1 414 ? 124.173 85.038  75.936  1.00 148.77 ? 414 ILE A N   1 
ATOM 3233 C CA  . ILE A 1 414 ? 124.354 85.702  74.649  1.00 148.77 ? 414 ILE A CA  1 
ATOM 3234 C C   . ILE A 1 414 ? 124.737 84.719  73.550  1.00 148.77 ? 414 ILE A C   1 
ATOM 3235 O O   . ILE A 1 414 ? 124.237 84.838  72.425  1.00 148.77 ? 414 ILE A O   1 
ATOM 3236 C CB  . ILE A 1 414 ? 125.398 86.827  74.749  1.00 148.77 ? 414 ILE A CB  1 
ATOM 3237 C CG1 . ILE A 1 414 ? 126.519 86.438  75.710  1.00 148.77 ? 414 ILE A CG1 1 
ATOM 3238 C CG2 . ILE A 1 414 ? 124.744 88.127  75.198  1.00 148.77 ? 414 ILE A CG2 1 
ATOM 3239 C CD1 . ILE A 1 414 ? 127.554 87.523  75.911  1.00 148.77 ? 414 ILE A CD1 1 
ATOM 3240 N N   . GLU A 1 415 ? 125.617 83.758  73.839  1.00 152.16 ? 415 GLU A N   1 
ATOM 3241 C CA  . GLU A 1 415 ? 125.909 82.710  72.867  1.00 152.16 ? 415 GLU A CA  1 
ATOM 3242 C C   . GLU A 1 415 ? 124.677 81.857  72.588  1.00 152.16 ? 415 GLU A C   1 
ATOM 3243 O O   . GLU A 1 415 ? 124.430 81.474  71.439  1.00 152.16 ? 415 GLU A O   1 
ATOM 3244 C CB  . GLU A 1 415 ? 127.070 81.844  73.359  1.00 152.16 ? 415 GLU A CB  1 
ATOM 3245 C CG  . GLU A 1 415 ? 128.314 82.636  73.739  1.00 152.16 ? 415 GLU A CG  1 
ATOM 3246 C CD  . GLU A 1 415 ? 128.856 83.471  72.594  1.00 152.16 ? 415 GLU A CD  1 
ATOM 3247 O OE1 . GLU A 1 415 ? 128.751 83.031  71.429  1.00 152.16 ? 415 GLU A OE1 1 
ATOM 3248 O OE2 . GLU A 1 415 ? 129.387 84.570  72.860  1.00 152.16 ? 415 GLU A OE2 1 
ATOM 3249 N N   . LEU A 1 416 ? 123.894 81.552  73.624  1.00 138.47 ? 416 LEU A N   1 
ATOM 3250 C CA  . LEU A 1 416 ? 122.625 80.857  73.451  1.00 138.47 ? 416 LEU A CA  1 
ATOM 3251 C C   . LEU A 1 416 ? 121.610 81.668  72.656  1.00 138.47 ? 416 LEU A C   1 
ATOM 3252 O O   . LEU A 1 416 ? 120.631 81.096  72.166  1.00 138.47 ? 416 LEU A O   1 
ATOM 3253 C CB  . LEU A 1 416 ? 122.033 80.486  74.815  1.00 138.47 ? 416 LEU A CB  1 
ATOM 3254 C CG  . LEU A 1 416 ? 122.684 79.310  75.550  1.00 138.47 ? 416 LEU A CG  1 
ATOM 3255 C CD1 . LEU A 1 416 ? 122.105 79.153  76.948  1.00 138.47 ? 416 LEU A CD1 1 
ATOM 3256 C CD2 . LEU A 1 416 ? 122.519 78.023  74.757  1.00 138.47 ? 416 LEU A CD2 1 
ATOM 3257 N N   . MET A 1 417 ? 121.806 82.982  72.533  1.00 134.32 ? 417 MET A N   1 
ATOM 3258 C CA  . MET A 1 417 ? 120.950 83.793  71.675  1.00 134.32 ? 417 MET A CA  1 
ATOM 3259 C C   . MET A 1 417 ? 121.321 83.650  70.202  1.00 134.32 ? 417 MET A C   1 
ATOM 3260 O O   . MET A 1 417 ? 120.703 84.296  69.349  1.00 134.32 ? 417 MET A O   1 
ATOM 3261 C CB  . MET A 1 417 ? 121.024 85.259  72.120  1.00 134.32 ? 417 MET A CB  1 
ATOM 3262 C CG  . MET A 1 417 ? 119.944 86.174  71.553  1.00 134.32 ? 417 MET A CG  1 
ATOM 3263 S SD  . MET A 1 417 ? 118.273 85.542  71.788  1.00 134.32 ? 417 MET A SD  1 
ATOM 3264 C CE  . MET A 1 417 ? 117.329 86.765  70.882  1.00 134.32 ? 417 MET A CE  1 
ATOM 3265 N N   . LYS A 1 418 ? 122.304 82.805  69.879  1.00 142.60 ? 418 LYS A N   1 
ATOM 3266 C CA  . LYS A 1 418 ? 122.782 82.666  68.511  1.00 142.60 ? 418 LYS A CA  1 
ATOM 3267 C C   . LYS A 1 418 ? 122.652 81.257  67.948  1.00 142.60 ? 418 LYS A C   1 
ATOM 3268 O O   . LYS A 1 418 ? 122.811 81.082  66.736  1.00 142.60 ? 418 LYS A O   1 
ATOM 3269 C CB  . LYS A 1 418 ? 124.251 83.108  68.416  1.00 142.60 ? 418 LYS A CB  1 
ATOM 3270 C CG  . LYS A 1 418 ? 124.701 83.525  67.021  1.00 142.60 ? 418 LYS A CG  1 
ATOM 3271 C CD  . LYS A 1 418 ? 123.829 84.641  66.460  1.00 142.60 ? 418 LYS A CD  1 
ATOM 3272 C CE  . LYS A 1 418 ? 123.939 85.909  67.292  1.00 142.60 ? 418 LYS A CE  1 
ATOM 3273 N NZ  . LYS A 1 418 ? 123.047 86.987  66.779  1.00 142.60 ? 418 LYS A NZ  1 
ATOM 3274 N N   . ASP A 1 419 ? 122.372 80.256  68.781  1.00 153.74 ? 419 ASP A N   1 
ATOM 3275 C CA  . ASP A 1 419 ? 122.259 78.894  68.281  1.00 153.74 ? 419 ASP A CA  1 
ATOM 3276 C C   . ASP A 1 419 ? 121.074 78.774  67.321  1.00 153.74 ? 419 ASP A C   1 
ATOM 3277 O O   . ASP A 1 419 ? 120.075 79.485  67.461  1.00 153.74 ? 419 ASP A O   1 
ATOM 3278 C CB  . ASP A 1 419 ? 122.110 77.903  69.434  1.00 153.74 ? 419 ASP A CB  1 
ATOM 3279 C CG  . ASP A 1 419 ? 120.978 78.260  70.378  1.00 153.74 ? 419 ASP A CG  1 
ATOM 3280 O OD1 . ASP A 1 419 ? 119.802 78.224  69.958  1.00 153.74 ? 419 ASP A OD1 1 
ATOM 3281 O OD2 . ASP A 1 419 ? 121.265 78.557  71.555  1.00 153.74 ? 419 ASP A OD2 1 
ATOM 3282 N N   . PRO A 1 420 ? 121.163 77.882  66.328  1.00 158.60 ? 420 PRO A N   1 
ATOM 3283 C CA  . PRO A 1 420 ? 120.112 77.803  65.300  1.00 158.60 ? 420 PRO A CA  1 
ATOM 3284 C C   . PRO A 1 420 ? 118.765 77.311  65.806  1.00 158.60 ? 420 PRO A C   1 
ATOM 3285 O O   . PRO A 1 420 ? 117.788 77.369  65.051  1.00 158.60 ? 420 PRO A O   1 
ATOM 3286 C CB  . PRO A 1 420 ? 120.701 76.820  64.275  1.00 158.60 ? 420 PRO A CB  1 
ATOM 3287 C CG  . PRO A 1 420 ? 121.689 76.016  65.044  1.00 158.60 ? 420 PRO A CG  1 
ATOM 3288 C CD  . PRO A 1 420 ? 122.274 76.954  66.055  1.00 158.60 ? 420 PRO A CD  1 
ATOM 3289 N N   . SER A 1 421 ? 118.671 76.833  67.044  1.00 152.13 ? 421 SER A N   1 
ATOM 3290 C CA  . SER A 1 421 ? 117.395 76.361  67.565  1.00 152.13 ? 421 SER A CA  1 
ATOM 3291 C C   . SER A 1 421 ? 116.469 77.540  67.841  1.00 152.13 ? 421 SER A C   1 
ATOM 3292 O O   . SER A 1 421 ? 116.804 78.441  68.617  1.00 152.13 ? 421 SER A O   1 
ATOM 3293 C CB  . SER A 1 421 ? 117.613 75.540  68.834  1.00 152.13 ? 421 SER A CB  1 
ATOM 3294 O OG  . SER A 1 421 ? 118.536 76.179  69.696  1.00 152.13 ? 421 SER A OG  1 
ATOM 3295 N N   . VAL A 1 422 ? 115.303 77.536  67.192  1.00 135.58 ? 422 VAL A N   1 
ATOM 3296 C CA  . VAL A 1 422 ? 114.377 78.659  67.308  1.00 135.58 ? 422 VAL A CA  1 
ATOM 3297 C C   . VAL A 1 422 ? 113.820 78.761  68.723  1.00 135.58 ? 422 VAL A C   1 
ATOM 3298 O O   . VAL A 1 422 ? 113.711 79.859  69.282  1.00 135.58 ? 422 VAL A O   1 
ATOM 3299 C CB  . VAL A 1 422 ? 113.254 78.531  66.264  1.00 135.58 ? 422 VAL A CB  1 
ATOM 3300 C CG1 . VAL A 1 422 ? 112.327 79.733  66.336  1.00 135.58 ? 422 VAL A CG1 1 
ATOM 3301 C CG2 . VAL A 1 422 ? 113.845 78.389  64.869  1.00 135.58 ? 422 VAL A CG2 1 
ATOM 3302 N N   . VAL A 1 423 ? 113.454 77.626  69.323  1.00 127.33 ? 423 VAL A N   1 
ATOM 3303 C CA  . VAL A 1 423 ? 112.809 77.656  70.633  1.00 127.33 ? 423 VAL A CA  1 
ATOM 3304 C C   . VAL A 1 423 ? 113.772 78.168  71.698  1.00 127.33 ? 423 VAL A C   1 
ATOM 3305 O O   . VAL A 1 423 ? 113.380 78.931  72.590  1.00 127.33 ? 423 VAL A O   1 
ATOM 3306 C CB  . VAL A 1 423 ? 112.259 76.264  70.992  1.00 127.33 ? 423 VAL A CB  1 
ATOM 3307 C CG1 . VAL A 1 423 ? 111.516 76.316  72.320  1.00 127.33 ? 423 VAL A CG1 1 
ATOM 3308 C CG2 . VAL A 1 423 ? 111.350 75.750  69.888  1.00 127.33 ? 423 VAL A CG2 1 
ATOM 3309 N N   . VAL A 1 424 ? 115.040 77.759  71.627  1.00 127.61 ? 424 VAL A N   1 
ATOM 3310 C CA  . VAL A 1 424 ? 116.017 78.193  72.622  1.00 127.61 ? 424 VAL A CA  1 
ATOM 3311 C C   . VAL A 1 424 ? 116.218 79.701  72.556  1.00 127.61 ? 424 VAL A C   1 
ATOM 3312 O O   . VAL A 1 424 ? 116.279 80.379  73.588  1.00 127.61 ? 424 VAL A O   1 
ATOM 3313 C CB  . VAL A 1 424 ? 117.342 77.432  72.436  1.00 127.61 ? 424 VAL A CB  1 
ATOM 3314 C CG1 . VAL A 1 424 ? 118.386 77.940  73.414  1.00 127.61 ? 424 VAL A CG1 1 
ATOM 3315 C CG2 . VAL A 1 424 ? 117.121 75.938  72.613  1.00 127.61 ? 424 VAL A CG2 1 
ATOM 3316 N N   . ARG A 1 425 ? 116.327 80.250  71.344  1.00 124.74 ? 425 ARG A N   1 
ATOM 3317 C CA  . ARG A 1 425 ? 116.453 81.696  71.196  1.00 124.74 ? 425 ARG A CA  1 
ATOM 3318 C C   . ARG A 1 425 ? 115.217 82.417  71.722  1.00 124.74 ? 425 ARG A C   1 
ATOM 3319 O O   . ARG A 1 425 ? 115.334 83.451  72.389  1.00 124.74 ? 425 ARG A O   1 
ATOM 3320 C CB  . ARG A 1 425 ? 116.717 82.053  69.734  1.00 124.74 ? 425 ARG A CB  1 
ATOM 3321 C CG  . ARG A 1 425 ? 118.195 82.241  69.421  1.00 124.74 ? 425 ARG A CG  1 
ATOM 3322 C CD  . ARG A 1 425 ? 118.497 82.193  67.930  1.00 124.74 ? 425 ARG A CD  1 
ATOM 3323 N NE  . ARG A 1 425 ? 117.615 83.046  67.144  1.00 124.74 ? 425 ARG A NE  1 
ATOM 3324 C CZ  . ARG A 1 425 ? 116.616 82.598  66.397  1.00 124.74 ? 425 ARG A CZ  1 
ATOM 3325 N NH1 . ARG A 1 425 ? 116.346 81.306  66.307  1.00 124.74 ? 425 ARG A NH1 1 
ATOM 3326 N NH2 . ARG A 1 425 ? 115.867 83.468  65.726  1.00 124.74 ? 425 ARG A NH2 1 
ATOM 3327 N N   . ASP A 1 426 ? 114.025 81.888  71.431  1.00 125.44 ? 426 ASP A N   1 
ATOM 3328 C CA  . ASP A 1 426 ? 112.812 82.438  72.028  1.00 125.44 ? 426 ASP A CA  1 
ATOM 3329 C C   . ASP A 1 426 ? 112.850 82.324  73.547  1.00 125.44 ? 426 ASP A C   1 
ATOM 3330 O O   . ASP A 1 426 ? 112.516 83.278  74.258  1.00 125.44 ? 426 ASP A O   1 
ATOM 3331 C CB  . ASP A 1 426 ? 111.579 81.726  71.471  1.00 125.44 ? 426 ASP A CB  1 
ATOM 3332 C CG  . ASP A 1 426 ? 110.281 82.343  71.955  1.00 125.44 ? 426 ASP A CG  1 
ATOM 3333 O OD1 . ASP A 1 426 ? 110.301 83.520  72.373  1.00 125.44 ? 426 ASP A OD1 1 
ATOM 3334 O OD2 . ASP A 1 426 ? 109.242 81.651  71.925  1.00 125.44 ? 426 ASP A OD2 1 
ATOM 3335 N N   . THR A 1 427 ? 113.252 81.159  74.062  1.00 115.80 ? 427 THR A N   1 
ATOM 3336 C CA  . THR A 1 427 ? 113.328 80.969  75.507  1.00 115.80 ? 427 THR A CA  1 
ATOM 3337 C C   . THR A 1 427 ? 114.368 81.889  76.136  1.00 115.80 ? 427 THR A C   1 
ATOM 3338 O O   . THR A 1 427 ? 114.129 82.469  77.202  1.00 115.80 ? 427 THR A O   1 
ATOM 3339 C CB  . THR A 1 427 ? 113.644 79.508  75.827  1.00 115.80 ? 427 THR A CB  1 
ATOM 3340 O OG1 . THR A 1 427 ? 112.629 78.665  75.268  1.00 115.80 ? 427 THR A OG1 1 
ATOM 3341 C CG2 . THR A 1 427 ? 113.696 79.292  77.327  1.00 115.80 ? 427 THR A CG2 1 
ATOM 3342 N N   . ALA A 1 428 ? 115.526 82.039  75.488  1.00 110.17 ? 428 ALA A N   1 
ATOM 3343 C CA  . ALA A 1 428 ? 116.580 82.884  76.039  1.00 110.17 ? 428 ALA A CA  1 
ATOM 3344 C C   . ALA A 1 428 ? 116.142 84.341  76.115  1.00 110.17 ? 428 ALA A C   1 
ATOM 3345 O O   . ALA A 1 428 ? 116.563 85.073  77.019  1.00 110.17 ? 428 ALA A O   1 
ATOM 3346 C CB  . ALA A 1 428 ? 117.853 82.749  75.205  1.00 110.17 ? 428 ALA A CB  1 
ATOM 3347 N N   . ALA A 1 429 ? 115.306 84.781  75.171  1.00 111.70 ? 429 ALA A N   1 
ATOM 3348 C CA  . ALA A 1 429 ? 114.839 86.164  75.178  1.00 111.70 ? 429 ALA A CA  1 
ATOM 3349 C C   . ALA A 1 429 ? 114.059 86.478  76.447  1.00 111.70 ? 429 ALA A C   1 
ATOM 3350 O O   . ALA A 1 429 ? 114.222 87.554  77.035  1.00 111.70 ? 429 ALA A O   1 
ATOM 3351 C CB  . ALA A 1 429 ? 113.981 86.433  73.941  1.00 111.70 ? 429 ALA A CB  1 
ATOM 3352 N N   . TRP A 1 430 ? 113.195 85.557  76.877  1.00 110.04 ? 430 TRP A N   1 
ATOM 3353 C CA  . TRP A 1 430 ? 112.466 85.757  78.125  1.00 110.04 ? 430 TRP A CA  1 
ATOM 3354 C C   . TRP A 1 430 ? 113.409 85.800  79.318  1.00 110.04 ? 430 TRP A C   1 
ATOM 3355 O O   . TRP A 1 430 ? 113.251 86.643  80.209  1.00 110.04 ? 430 TRP A O   1 
ATOM 3356 C CB  . TRP A 1 430 ? 111.426 84.656  78.314  1.00 110.04 ? 430 TRP A CB  1 
ATOM 3357 C CG  . TRP A 1 430 ? 110.669 84.781  79.595  1.00 110.04 ? 430 TRP A CG  1 
ATOM 3358 C CD1 . TRP A 1 430 ? 109.687 85.683  79.880  1.00 110.04 ? 430 TRP A CD1 1 
ATOM 3359 C CD2 . TRP A 1 430 ? 110.827 83.975  80.769  1.00 110.04 ? 430 TRP A CD2 1 
ATOM 3360 N NE1 . TRP A 1 430 ? 109.225 85.492  81.158  1.00 110.04 ? 430 TRP A NE1 1 
ATOM 3361 C CE2 . TRP A 1 430 ? 109.908 84.447  81.724  1.00 110.04 ? 430 TRP A CE2 1 
ATOM 3362 C CE3 . TRP A 1 430 ? 111.656 82.901  81.105  1.00 110.04 ? 430 TRP A CE3 1 
ATOM 3363 C CZ2 . TRP A 1 430 ? 109.795 83.885  82.990  1.00 110.04 ? 430 TRP A CZ2 1 
ATOM 3364 C CZ3 . TRP A 1 430 ? 111.542 82.344  82.363  1.00 110.04 ? 430 TRP A CZ3 1 
ATOM 3365 C CH2 . TRP A 1 430 ? 110.619 82.836  83.290  1.00 110.04 ? 430 TRP A CH2 1 
ATOM 3366 N N   . THR A 1 431 ? 114.391 84.896  79.357  1.00 109.44 ? 431 THR A N   1 
ATOM 3367 C CA  . THR A 1 431 ? 115.298 84.836  80.499  1.00 109.44 ? 431 THR A CA  1 
ATOM 3368 C C   . THR A 1 431 ? 116.107 86.120  80.637  1.00 109.44 ? 431 THR A C   1 
ATOM 3369 O O   . THR A 1 431 ? 116.223 86.668  81.739  1.00 109.44 ? 431 THR A O   1 
ATOM 3370 C CB  . THR A 1 431 ? 116.223 83.628  80.370  1.00 109.44 ? 431 THR A CB  1 
ATOM 3371 O OG1 . THR A 1 431 ? 117.028 83.760  79.190  1.00 109.44 ? 431 THR A OG1 1 
ATOM 3372 C CG2 . THR A 1 431 ? 115.402 82.347  80.287  1.00 109.44 ? 431 THR A CG2 1 
ATOM 3373 N N   . VAL A 1 432 ? 116.669 86.621  79.535  1.00 106.67 ? 432 VAL A N   1 
ATOM 3374 C CA  . VAL A 1 432 ? 117.367 87.901  79.604  1.00 106.67 ? 432 VAL A CA  1 
ATOM 3375 C C   . VAL A 1 432 ? 116.378 89.033  79.862  1.00 106.67 ? 432 VAL A C   1 
ATOM 3376 O O   . VAL A 1 432 ? 116.695 89.994  80.573  1.00 106.67 ? 432 VAL A O   1 
ATOM 3377 C CB  . VAL A 1 432 ? 118.207 88.138  78.332  1.00 106.67 ? 432 VAL A CB  1 
ATOM 3378 C CG1 . VAL A 1 432 ? 117.328 88.250  77.093  1.00 106.67 ? 432 VAL A CG1 1 
ATOM 3379 C CG2 . VAL A 1 432 ? 119.076 89.376  78.492  1.00 106.67 ? 432 VAL A CG2 1 
ATOM 3380 N N   . GLY A 1 433 ? 115.170 88.944  79.300  1.00 111.13 ? 433 GLY A N   1 
ATOM 3381 C CA  . GLY A 1 433 ? 114.145 89.926  79.613  1.00 111.13 ? 433 GLY A CA  1 
ATOM 3382 C C   . GLY A 1 433 ? 113.724 89.885  81.069  1.00 111.13 ? 433 GLY A C   1 
ATOM 3383 O O   . GLY A 1 433 ? 113.554 90.928  81.705  1.00 111.13 ? 433 GLY A O   1 
ATOM 3384 N N   . ARG A 1 434 ? 113.543 88.681  81.617  1.00 113.69 ? 434 ARG A N   1 
ATOM 3385 C CA  . ARG A 1 434 ? 113.205 88.559  83.031  1.00 113.69 ? 434 ARG A CA  1 
ATOM 3386 C C   . ARG A 1 434 ? 114.345 89.048  83.916  1.00 113.69 ? 434 ARG A C   1 
ATOM 3387 O O   . ARG A 1 434 ? 114.109 89.729  84.921  1.00 113.69 ? 434 ARG A O   1 
ATOM 3388 C CB  . ARG A 1 434 ? 112.852 87.109  83.366  1.00 113.69 ? 434 ARG A CB  1 
ATOM 3389 C CG  . ARG A 1 434 ? 112.634 86.846  84.848  1.00 113.69 ? 434 ARG A CG  1 
ATOM 3390 C CD  . ARG A 1 434 ? 111.309 87.406  85.340  1.00 113.69 ? 434 ARG A CD  1 
ATOM 3391 N NE  . ARG A 1 434 ? 110.236 86.423  85.251  1.00 113.69 ? 434 ARG A NE  1 
ATOM 3392 C CZ  . ARG A 1 434 ? 109.965 85.525  86.189  1.00 113.69 ? 434 ARG A CZ  1 
ATOM 3393 N NH1 . ARG A 1 434 ? 110.674 85.456  87.304  1.00 113.69 ? 434 ARG A NH1 1 
ATOM 3394 N NH2 . ARG A 1 434 ? 108.959 84.675  86.003  1.00 113.69 ? 434 ARG A NH2 1 
ATOM 3395 N N   . ILE A 1 435 ? 115.587 88.715  83.556  1.00 114.80 ? 435 ILE A N   1 
ATOM 3396 C CA  . ILE A 1 435 ? 116.727 89.089  84.386  1.00 114.80 ? 435 ILE A CA  1 
ATOM 3397 C C   . ILE A 1 435 ? 116.948 90.597  84.417  1.00 114.80 ? 435 ILE A C   1 
ATOM 3398 O O   . ILE A 1 435 ? 117.530 91.107  85.382  1.00 114.80 ? 435 ILE A O   1 
ATOM 3399 C CB  . ILE A 1 435 ? 118.003 88.361  83.922  1.00 114.80 ? 435 ILE A CB  1 
ATOM 3400 C CG1 . ILE A 1 435 ? 118.924 88.090  85.111  1.00 114.80 ? 435 ILE A CG1 1 
ATOM 3401 C CG2 . ILE A 1 435 ? 118.749 89.163  82.867  1.00 114.80 ? 435 ILE A CG2 1 
ATOM 3402 C CD1 . ILE A 1 435 ? 120.211 87.389  84.733  1.00 114.80 ? 435 ILE A CD1 1 
ATOM 3403 N N   . CYS A 1 436 ? 116.508 91.327  83.389  1.00 110.57 ? 436 CYS A N   1 
ATOM 3404 C CA  . CYS A 1 436 ? 116.620 92.781  83.418  1.00 110.57 ? 436 CYS A CA  1 
ATOM 3405 C C   . CYS A 1 436 ? 115.628 93.396  84.397  1.00 110.57 ? 436 CYS A C   1 
ATOM 3406 O O   . CYS A 1 436 ? 115.979 94.316  85.145  1.00 110.57 ? 436 CYS A O   1 
ATOM 3407 C CB  . CYS A 1 436 ? 116.410 93.356  82.016  1.00 110.57 ? 436 CYS A CB  1 
ATOM 3408 S SG  . CYS A 1 436 ? 117.742 92.998  80.847  1.00 110.57 ? 436 CYS A SG  1 
ATOM 3409 N N   . GLU A 1 437 ? 114.386 92.908  84.396  1.00 123.78 ? 437 GLU A N   1 
ATOM 3410 C CA  . GLU A 1 437 ? 113.360 93.459  85.275  1.00 123.78 ? 437 GLU A CA  1 
ATOM 3411 C C   . GLU A 1 437 ? 113.679 93.189  86.742  1.00 123.78 ? 437 GLU A C   1 
ATOM 3412 O O   . GLU A 1 437 ? 113.501 94.064  87.598  1.00 123.78 ? 437 GLU A O   1 
ATOM 3413 C CB  . GLU A 1 437 ? 111.993 92.878  84.905  1.00 123.78 ? 437 GLU A CB  1 
ATOM 3414 C CG  . GLU A 1 437 ? 111.631 93.034  83.433  1.00 123.78 ? 437 GLU A CG  1 
ATOM 3415 C CD  . GLU A 1 437 ? 110.292 92.415  83.084  1.00 123.78 ? 437 GLU A CD  1 
ATOM 3416 O OE1 . GLU A 1 437 ? 109.690 91.759  83.959  1.00 123.78 ? 437 GLU A OE1 1 
ATOM 3417 O OE2 . GLU A 1 437 ? 109.842 92.584  81.932  1.00 123.78 ? 437 GLU A OE2 1 
ATOM 3418 N N   . LEU A 1 438 ? 114.156 91.983  87.052  1.00 122.59 ? 438 LEU A N   1 
ATOM 3419 C CA  . LEU A 1 438 ? 114.309 91.576  88.446  1.00 122.59 ? 438 LEU A CA  1 
ATOM 3420 C C   . LEU A 1 438 ? 115.708 91.876  88.975  1.00 122.59 ? 438 LEU A C   1 
ATOM 3421 O O   . LEU A 1 438 ? 115.894 92.094  90.176  1.00 122.59 ? 438 LEU A O   1 
ATOM 3422 C CB  . LEU A 1 438 ? 113.983 90.087  88.594  1.00 122.59 ? 438 LEU A CB  1 
ATOM 3423 C CG  . LEU A 1 438 ? 112.525 89.703  88.866  1.00 122.59 ? 438 LEU A CG  1 
ATOM 3424 C CD1 . LEU A 1 438 ? 111.595 90.193  87.765  1.00 122.59 ? 438 LEU A CD1 1 
ATOM 3425 C CD2 . LEU A 1 438 ? 112.402 88.198  89.039  1.00 122.59 ? 438 LEU A CD2 1 
ATOM 3426 N N   . LEU A 1 439 ? 116.703 91.893  88.094  1.00 129.53 ? 439 LEU A N   1 
ATOM 3427 C CA  . LEU A 1 439 ? 118.076 92.171  88.500  1.00 129.53 ? 439 LEU A CA  1 
ATOM 3428 C C   . LEU A 1 439 ? 118.606 93.351  87.702  1.00 129.53 ? 439 LEU A C   1 
ATOM 3429 O O   . LEU A 1 439 ? 119.233 93.147  86.650  1.00 129.53 ? 439 LEU A O   1 
ATOM 3430 C CB  . LEU A 1 439 ? 118.964 90.943  88.289  1.00 129.53 ? 439 LEU A CB  1 
ATOM 3431 C CG  . LEU A 1 439 ? 118.512 89.647  88.966  1.00 129.53 ? 439 LEU A CG  1 
ATOM 3432 C CD1 . LEU A 1 439 ? 119.517 88.539  88.713  1.00 129.53 ? 439 LEU A CD1 1 
ATOM 3433 C CD2 . LEU A 1 439 ? 118.313 89.857  90.456  1.00 129.53 ? 439 LEU A CD2 1 
ATOM 3434 N N   . PRO A 1 440 ? 118.385 94.592  88.146  1.00 145.01 ? 440 PRO A N   1 
ATOM 3435 C CA  . PRO A 1 440 ? 118.825 95.750  87.355  1.00 145.01 ? 440 PRO A CA  1 
ATOM 3436 C C   . PRO A 1 440 ? 120.335 95.841  87.202  1.00 145.01 ? 440 PRO A C   1 
ATOM 3437 O O   . PRO A 1 440 ? 120.838 95.995  86.085  1.00 145.01 ? 440 PRO A O   1 
ATOM 3438 C CB  . PRO A 1 440 ? 118.280 96.946  88.149  1.00 145.01 ? 440 PRO A CB  1 
ATOM 3439 C CG  . PRO A 1 440 ? 117.177 96.388  88.984  1.00 145.01 ? 440 PRO A CG  1 
ATOM 3440 C CD  . PRO A 1 440 ? 117.607 94.995  89.329  1.00 145.01 ? 440 PRO A CD  1 
ATOM 3441 N N   . GLU A 1 441 ? 121.064 95.744  88.318  1.00 164.33 ? 441 GLU A N   1 
ATOM 3442 C CA  . GLU A 1 441 ? 122.509 95.950  88.284  1.00 164.33 ? 441 GLU A CA  1 
ATOM 3443 C C   . GLU A 1 441 ? 123.224 94.890  87.455  1.00 164.33 ? 441 GLU A C   1 
ATOM 3444 O O   . GLU A 1 441 ? 124.163 95.214  86.720  1.00 164.33 ? 441 GLU A O   1 
ATOM 3445 C CB  . GLU A 1 441 ? 123.071 95.981  89.707  1.00 164.33 ? 441 GLU A CB  1 
ATOM 3446 C CG  . GLU A 1 441 ? 122.210 95.272  90.746  1.00 164.33 ? 441 GLU A CG  1 
ATOM 3447 C CD  . GLU A 1 441 ? 122.232 93.761  90.610  1.00 164.33 ? 441 GLU A CD  1 
ATOM 3448 O OE1 . GLU A 1 441 ? 123.224 93.222  90.076  1.00 164.33 ? 441 GLU A OE1 1 
ATOM 3449 O OE2 . GLU A 1 441 ? 121.256 93.110  91.039  1.00 164.33 ? 441 GLU A OE2 1 
ATOM 3450 N N   . ALA A 1 442 ? 122.802 93.629  87.559  1.00 161.03 ? 442 ALA A N   1 
ATOM 3451 C CA  . ALA A 1 442 ? 123.462 92.569  86.804  1.00 161.03 ? 442 ALA A CA  1 
ATOM 3452 C C   . ALA A 1 442 ? 123.255 92.731  85.304  1.00 161.03 ? 442 ALA A C   1 
ATOM 3453 O O   . ALA A 1 442 ? 124.137 92.370  84.516  1.00 161.03 ? 442 ALA A O   1 
ATOM 3454 C CB  . ALA A 1 442 ? 122.960 91.201  87.264  1.00 161.03 ? 442 ALA A CB  1 
ATOM 3455 N N   . ALA A 1 443 ? 122.101 93.261  84.891  1.00 150.98 ? 443 ALA A N   1 
ATOM 3456 C CA  . ALA A 1 443 ? 121.810 93.420  83.471  1.00 150.98 ? 443 ALA A CA  1 
ATOM 3457 C C   . ALA A 1 443 ? 122.666 94.491  82.806  1.00 150.98 ? 443 ALA A C   1 
ATOM 3458 O O   . ALA A 1 443 ? 122.776 94.497  81.576  1.00 150.98 ? 443 ALA A O   1 
ATOM 3459 C CB  . ALA A 1 443 ? 120.329 93.746  83.274  1.00 150.98 ? 443 ALA A CB  1 
ATOM 3460 N N   . ILE A 1 444 ? 123.267 95.393  83.576  1.00 158.40 ? 444 ILE A N   1 
ATOM 3461 C CA  . ILE A 1 444 ? 124.089 96.470  83.034  1.00 158.40 ? 444 ILE A CA  1 
ATOM 3462 C C   . ILE A 1 444 ? 125.503 96.282  83.570  1.00 158.40 ? 444 ILE A C   1 
ATOM 3463 O O   . ILE A 1 444 ? 125.827 96.712  84.683  1.00 158.40 ? 444 ILE A O   1 
ATOM 3464 C CB  . ILE A 1 444 ? 123.532 97.856  83.381  1.00 158.40 ? 444 ILE A CB  1 
ATOM 3465 C CG1 . ILE A 1 444 ? 122.977 97.879  84.807  1.00 158.40 ? 444 ILE A CG1 1 
ATOM 3466 C CG2 . ILE A 1 444 ? 122.464 98.267  82.380  1.00 158.40 ? 444 ILE A CG2 1 
ATOM 3467 C CD1 . ILE A 1 444 ? 122.406 99.217  85.221  1.00 158.40 ? 444 ILE A CD1 1 
ATOM 3468 N N   . ASN A 1 445 ? 126.352 95.634  82.776  1.00 167.77 ? 445 ASN A N   1 
ATOM 3469 C CA  . ASN A 1 445 ? 127.766 95.486  83.105  1.00 167.77 ? 445 ASN A CA  1 
ATOM 3470 C C   . ASN A 1 445 ? 128.560 95.664  81.822  1.00 167.77 ? 445 ASN A C   1 
ATOM 3471 O O   . ASN A 1 445 ? 128.332 94.935  80.852  1.00 167.77 ? 445 ASN A O   1 
ATOM 3472 C CB  . ASN A 1 445 ? 128.050 94.123  83.741  1.00 167.77 ? 445 ASN A CB  1 
ATOM 3473 C CG  . ASN A 1 445 ? 129.439 94.039  84.343  1.00 167.77 ? 445 ASN A CG  1 
ATOM 3474 O OD1 . ASN A 1 445 ? 130.384 93.590  83.695  1.00 167.77 ? 445 ASN A OD1 1 
ATOM 3475 N ND2 . ASN A 1 445 ? 129.569 94.473  85.592  1.00 167.77 ? 445 ASN A ND2 1 
ATOM 3476 N N   . ASP A 1 446 ? 129.490 96.624  81.822  1.00 182.95 ? 446 ASP A N   1 
ATOM 3477 C CA  . ASP A 1 446 ? 130.204 96.988  80.602  1.00 182.95 ? 446 ASP A CA  1 
ATOM 3478 C C   . ASP A 1 446 ? 130.982 95.823  80.003  1.00 182.95 ? 446 ASP A C   1 
ATOM 3479 O O   . ASP A 1 446 ? 131.196 95.800  78.786  1.00 182.95 ? 446 ASP A O   1 
ATOM 3480 C CB  . ASP A 1 446 ? 131.155 98.155  80.876  1.00 182.95 ? 446 ASP A CB  1 
ATOM 3481 C CG  . ASP A 1 446 ? 131.634 98.829  79.603  1.00 182.95 ? 446 ASP A CG  1 
ATOM 3482 O OD1 . ASP A 1 446 ? 131.033 98.587  78.535  1.00 182.95 ? 446 ASP A OD1 1 
ATOM 3483 O OD2 . ASP A 1 446 ? 132.613 99.602  79.668  1.00 182.95 ? 446 ASP A OD2 1 
ATOM 3484 N N   . VAL A 1 447 ? 131.410 94.861  80.823  1.00 174.66 ? 447 VAL A N   1 
ATOM 3485 C CA  . VAL A 1 447 ? 132.094 93.686  80.292  1.00 174.66 ? 447 VAL A CA  1 
ATOM 3486 C C   . VAL A 1 447 ? 131.155 92.882  79.400  1.00 174.66 ? 447 VAL A C   1 
ATOM 3487 O O   . VAL A 1 447 ? 131.595 92.188  78.475  1.00 174.66 ? 447 VAL A O   1 
ATOM 3488 C CB  . VAL A 1 447 ? 132.656 92.832  81.444  1.00 174.66 ? 447 VAL A CB  1 
ATOM 3489 C CG1 . VAL A 1 447 ? 133.528 91.706  80.906  1.00 174.66 ? 447 VAL A CG1 1 
ATOM 3490 C CG2 . VAL A 1 447 ? 133.443 93.702  82.413  1.00 174.66 ? 447 VAL A CG2 1 
ATOM 3491 N N   . TYR A 1 448 ? 129.850 92.971  79.653  1.00 170.72 ? 448 TYR A N   1 
ATOM 3492 C CA  . TYR A 1 448 ? 128.862 92.228  78.887  1.00 170.72 ? 448 TYR A CA  1 
ATOM 3493 C C   . TYR A 1 448 ? 127.806 93.114  78.242  1.00 170.72 ? 448 TYR A C   1 
ATOM 3494 O O   . TYR A 1 448 ? 126.997 92.608  77.457  1.00 170.72 ? 448 TYR A O   1 
ATOM 3495 C CB  . TYR A 1 448 ? 128.173 91.187  79.780  1.00 170.72 ? 448 TYR A CB  1 
ATOM 3496 C CG  . TYR A 1 448 ? 129.107 90.516  80.762  1.00 170.72 ? 448 TYR A CG  1 
ATOM 3497 C CD1 . TYR A 1 448 ? 129.859 89.409  80.392  1.00 170.72 ? 448 TYR A CD1 1 
ATOM 3498 C CD2 . TYR A 1 448 ? 129.235 90.991  82.061  1.00 170.72 ? 448 TYR A CD2 1 
ATOM 3499 C CE1 . TYR A 1 448 ? 130.714 88.795  81.288  1.00 170.72 ? 448 TYR A CE1 1 
ATOM 3500 C CE2 . TYR A 1 448 ? 130.087 90.385  82.963  1.00 170.72 ? 448 TYR A CE2 1 
ATOM 3501 C CZ  . TYR A 1 448 ? 130.824 89.287  82.572  1.00 170.72 ? 448 TYR A CZ  1 
ATOM 3502 O OH  . TYR A 1 448 ? 131.673 88.680  83.469  1.00 170.72 ? 448 TYR A OH  1 
ATOM 3503 N N   . LEU A 1 449 ? 127.785 94.414  78.547  1.00 158.97 ? 449 LEU A N   1 
ATOM 3504 C CA  . LEU A 1 449 ? 126.753 95.294  78.004  1.00 158.97 ? 449 LEU A CA  1 
ATOM 3505 C C   . LEU A 1 449 ? 126.840 95.384  76.485  1.00 158.97 ? 449 LEU A C   1 
ATOM 3506 O O   . LEU A 1 449 ? 125.866 95.102  75.777  1.00 158.97 ? 449 LEU A O   1 
ATOM 3507 C CB  . LEU A 1 449 ? 126.863 96.686  78.631  1.00 158.97 ? 449 LEU A CB  1 
ATOM 3508 C CG  . LEU A 1 449 ? 125.885 97.005  79.763  1.00 158.97 ? 449 LEU A CG  1 
ATOM 3509 C CD1 . LEU A 1 449 ? 126.131 98.402  80.309  1.00 158.97 ? 449 LEU A CD1 1 
ATOM 3510 C CD2 . LEU A 1 449 ? 124.451 96.864  79.282  1.00 158.97 ? 449 LEU A CD2 1 
ATOM 3511 N N   . ALA A 1 450 ? 128.003 95.781  75.967  1.00 152.69 ? 450 ALA A N   1 
ATOM 3512 C CA  . ALA A 1 450 ? 128.141 95.980  74.527  1.00 152.69 ? 450 ALA A CA  1 
ATOM 3513 C C   . ALA A 1 450 ? 127.816 94.735  73.707  1.00 152.69 ? 450 ALA A C   1 
ATOM 3514 O O   . ALA A 1 450 ? 127.069 94.865  72.721  1.00 152.69 ? 450 ALA A O   1 
ATOM 3515 C CB  . ALA A 1 450 ? 129.550 96.499  74.205  1.00 152.69 ? 450 ALA A CB  1 
ATOM 3516 N N   . PRO A 1 451 ? 128.318 93.534  74.025  1.00 146.59 ? 451 PRO A N   1 
ATOM 3517 C CA  . PRO A 1 451 ? 127.855 92.355  73.272  1.00 146.59 ? 451 PRO A CA  1 
ATOM 3518 C C   . PRO A 1 451 ? 126.375 92.071  73.459  1.00 146.59 ? 451 PRO A C   1 
ATOM 3519 O O   . PRO A 1 451 ? 125.687 91.740  72.485  1.00 146.59 ? 451 PRO A O   1 
ATOM 3520 C CB  . PRO A 1 451 ? 128.733 91.221  73.820  1.00 146.59 ? 451 PRO A CB  1 
ATOM 3521 C CG  . PRO A 1 451 ? 129.176 91.692  75.156  1.00 146.59 ? 451 PRO A CG  1 
ATOM 3522 C CD  . PRO A 1 451 ? 129.348 93.170  75.016  1.00 146.59 ? 451 PRO A CD  1 
ATOM 3523 N N   . LEU A 1 452 ? 125.863 92.187  74.688  1.00 131.29 ? 452 LEU A N   1 
ATOM 3524 C CA  . LEU A 1 452 ? 124.440 91.956  74.921  1.00 131.29 ? 452 LEU A CA  1 
ATOM 3525 C C   . LEU A 1 452 ? 123.584 92.964  74.168  1.00 131.29 ? 452 LEU A C   1 
ATOM 3526 O O   . LEU A 1 452 ? 122.601 92.587  73.519  1.00 131.29 ? 452 LEU A O   1 
ATOM 3527 C CB  . LEU A 1 452 ? 124.132 92.015  76.417  1.00 131.29 ? 452 LEU A CB  1 
ATOM 3528 C CG  . LEU A 1 452 ? 122.655 92.072  76.815  1.00 131.29 ? 452 LEU A CG  1 
ATOM 3529 C CD1 . LEU A 1 452 ? 121.930 90.804  76.397  1.00 131.29 ? 452 LEU A CD1 1 
ATOM 3530 C CD2 . LEU A 1 452 ? 122.510 92.312  78.312  1.00 131.29 ? 452 LEU A CD2 1 
ATOM 3531 N N   . LEU A 1 453 ? 123.949 94.246  74.230  1.00 144.09 ? 453 LEU A N   1 
ATOM 3532 C CA  . LEU A 1 453 ? 123.155 95.278  73.572  1.00 144.09 ? 453 LEU A CA  1 
ATOM 3533 C C   . LEU A 1 453 ? 123.131 95.078  72.062  1.00 144.09 ? 453 LEU A C   1 
ATOM 3534 O O   . LEU A 1 453 ? 122.092 95.278  71.422  1.00 144.09 ? 453 LEU A O   1 
ATOM 3535 C CB  . LEU A 1 453 ? 123.701 96.661  73.927  1.00 144.09 ? 453 LEU A CB  1 
ATOM 3536 C CG  . LEU A 1 453 ? 122.920 97.887  73.449  1.00 144.09 ? 453 LEU A CG  1 
ATOM 3537 C CD1 . LEU A 1 453 ? 121.497 97.853  73.969  1.00 144.09 ? 453 LEU A CD1 1 
ATOM 3538 C CD2 . LEU A 1 453 ? 123.624 99.160  73.895  1.00 144.09 ? 453 LEU A CD2 1 
ATOM 3539 N N   . GLN A 1 454 ? 124.264 94.685  71.476  1.00 143.79 ? 454 GLN A N   1 
ATOM 3540 C CA  . GLN A 1 454 ? 124.310 94.446  70.037  1.00 143.79 ? 454 GLN A CA  1 
ATOM 3541 C C   . GLN A 1 454 ? 123.448 93.251  69.647  1.00 143.79 ? 454 GLN A C   1 
ATOM 3542 O O   . GLN A 1 454 ? 122.804 93.256  68.591  1.00 143.79 ? 454 GLN A O   1 
ATOM 3543 C CB  . GLN A 1 454 ? 125.757 94.237  69.588  1.00 143.79 ? 454 GLN A CB  1 
ATOM 3544 C CG  . GLN A 1 454 ? 125.926 94.021  68.093  1.00 143.79 ? 454 GLN A CG  1 
ATOM 3545 C CD  . GLN A 1 454 ? 125.456 95.206  67.273  1.00 143.79 ? 454 GLN A CD  1 
ATOM 3546 O OE1 . GLN A 1 454 ? 124.879 95.041  66.199  1.00 143.79 ? 454 GLN A OE1 1 
ATOM 3547 N NE2 . GLN A 1 454 ? 125.706 96.411  67.774  1.00 143.79 ? 454 GLN A NE2 1 
ATOM 3548 N N   . CYS A 1 455 ? 123.431 92.211  70.484  1.00 140.36 ? 455 CYS A N   1 
ATOM 3549 C CA  . CYS A 1 455 ? 122.595 91.048  70.203  1.00 140.36 ? 455 CYS A CA  1 
ATOM 3550 C C   . CYS A 1 455 ? 121.119 91.414  70.222  1.00 140.36 ? 455 CYS A C   1 
ATOM 3551 O O   . CYS A 1 455 ? 120.339 90.924  69.395  1.00 140.36 ? 455 CYS A O   1 
ATOM 3552 C CB  . CYS A 1 455 ? 122.885 89.936  71.208  1.00 140.36 ? 455 CYS A CB  1 
ATOM 3553 S SG  . CYS A 1 455 ? 124.481 89.130  70.968  1.00 140.36 ? 455 CYS A SG  1 
ATOM 3554 N N   . LEU A 1 456 ? 120.714 92.263  71.167  1.00 119.93 ? 456 LEU A N   1 
ATOM 3555 C CA  . LEU A 1 456 ? 119.322 92.686  71.239  1.00 119.93 ? 456 LEU A CA  1 
ATOM 3556 C C   . LEU A 1 456 ? 118.879 93.402  69.970  1.00 119.93 ? 456 LEU A C   1 
ATOM 3557 O O   . LEU A 1 456 ? 117.780 93.141  69.470  1.00 119.93 ? 456 LEU A O   1 
ATOM 3558 C CB  . LEU A 1 456 ? 119.110 93.594  72.453  1.00 119.93 ? 456 LEU A CB  1 
ATOM 3559 C CG  . LEU A 1 456 ? 119.495 93.056  73.834  1.00 119.93 ? 456 LEU A CG  1 
ATOM 3560 C CD1 . LEU A 1 456 ? 119.131 94.047  74.927  1.00 119.93 ? 456 LEU A CD1 1 
ATOM 3561 C CD2 . LEU A 1 456 ? 118.843 91.714  74.097  1.00 119.93 ? 456 LEU A CD2 1 
ATOM 3562 N N   . ILE A 1 457 ? 119.716 94.297  69.438  1.00 132.76 ? 457 ILE A N   1 
ATOM 3563 C CA  . ILE A 1 457 ? 119.351 95.040  68.235  1.00 132.76 ? 457 ILE A CA  1 
ATOM 3564 C C   . ILE A 1 457 ? 119.212 94.101  67.044  1.00 132.76 ? 457 ILE A C   1 
ATOM 3565 O O   . ILE A 1 457 ? 118.258 94.200  66.263  1.00 132.76 ? 457 ILE A O   1 
ATOM 3566 C CB  . ILE A 1 457 ? 120.382 96.151  67.964  1.00 132.76 ? 457 ILE A CB  1 
ATOM 3567 C CG1 . ILE A 1 457 ? 120.552 97.026  69.205  1.00 132.76 ? 457 ILE A CG1 1 
ATOM 3568 C CG2 . ILE A 1 457 ? 119.960 96.994  66.768  1.00 132.76 ? 457 ILE A CG2 1 
ATOM 3569 C CD1 . ILE A 1 457 ? 121.663 98.040  69.085  1.00 132.76 ? 457 ILE A CD1 1 
ATOM 3570 N N   . GLU A 1 458 ? 120.167 93.184  66.876  1.00 139.99 ? 458 GLU A N   1 
ATOM 3571 C CA  . GLU A 1 458 ? 120.078 92.215  65.789  1.00 139.99 ? 458 GLU A CA  1 
ATOM 3572 C C   . GLU A 1 458 ? 118.912 91.257  66.000  1.00 139.99 ? 458 GLU A C   1 
ATOM 3573 O O   . GLU A 1 458 ? 118.294 90.798  65.032  1.00 139.99 ? 458 GLU A O   1 
ATOM 3574 C CB  . GLU A 1 458 ? 121.395 91.446  65.663  1.00 139.99 ? 458 GLU A CB  1 
ATOM 3575 C CG  . GLU A 1 458 ? 122.608 92.334  65.403  1.00 139.99 ? 458 GLU A CG  1 
ATOM 3576 C CD  . GLU A 1 458 ? 123.916 91.564  65.400  1.00 139.99 ? 458 GLU A CD  1 
ATOM 3577 O OE1 . GLU A 1 458 ? 123.880 90.316  65.416  1.00 139.99 ? 458 GLU A OE1 1 
ATOM 3578 O OE2 . GLU A 1 458 ? 124.985 92.210  65.385  1.00 139.99 ? 458 GLU A OE2 1 
ATOM 3579 N N   . GLY A 1 459 ? 118.595 90.950  67.261  1.00 141.70 ? 459 GLY A N   1 
ATOM 3580 C CA  . GLY A 1 459 ? 117.535 90.007  67.571  1.00 141.70 ? 459 GLY A CA  1 
ATOM 3581 C C   . GLY A 1 459 ? 116.161 90.407  67.083  1.00 141.70 ? 459 GLY A C   1 
ATOM 3582 O O   . GLY A 1 459 ? 115.427 89.552  66.579  1.00 141.70 ? 459 GLY A O   1 
ATOM 3583 N N   . LEU A 1 460 ? 115.796 91.684  67.220  1.00 137.14 ? 460 LEU A N   1 
ATOM 3584 C CA  . LEU A 1 460 ? 114.460 92.138  66.851  1.00 137.14 ? 460 LEU A CA  1 
ATOM 3585 C C   . LEU A 1 460 ? 114.187 92.049  65.354  1.00 137.14 ? 460 LEU A C   1 
ATOM 3586 O O   . LEU A 1 460 ? 113.018 92.090  64.956  1.00 137.14 ? 460 LEU A O   1 
ATOM 3587 C CB  . LEU A 1 460 ? 114.243 93.574  67.340  1.00 137.14 ? 460 LEU A CB  1 
ATOM 3588 C CG  . LEU A 1 460 ? 115.192 94.685  66.878  1.00 137.14 ? 460 LEU A CG  1 
ATOM 3589 C CD1 . LEU A 1 460 ? 114.723 95.332  65.583  1.00 137.14 ? 460 LEU A CD1 1 
ATOM 3590 C CD2 . LEU A 1 460 ? 115.348 95.731  67.972  1.00 137.14 ? 460 LEU A CD2 1 
ATOM 3591 N N   . SER A 1 461 ? 115.218 91.934  64.520  1.00 141.04 ? 461 SER A N   1 
ATOM 3592 C CA  . SER A 1 461 ? 115.025 91.783  63.082  1.00 141.04 ? 461 SER A CA  1 
ATOM 3593 C C   . SER A 1 461 ? 114.641 90.364  62.682  1.00 141.04 ? 461 SER A C   1 
ATOM 3594 O O   . SER A 1 461 ? 114.332 90.128  61.508  1.00 141.04 ? 461 SER A O   1 
ATOM 3595 C CB  . SER A 1 461 ? 116.293 92.203  62.331  1.00 141.04 ? 461 SER A CB  1 
ATOM 3596 O OG  . SER A 1 461 ? 117.412 91.444  62.752  1.00 141.04 ? 461 SER A OG  1 
ATOM 3597 N N   . ALA A 1 462 ? 114.662 89.421  63.623  1.00 145.67 ? 462 ALA A N   1 
ATOM 3598 C CA  . ALA A 1 462 ? 114.334 88.025  63.360  1.00 145.67 ? 462 ALA A CA  1 
ATOM 3599 C C   . ALA A 1 462 ? 112.829 87.793  63.350  1.00 145.67 ? 462 ALA A C   1 
ATOM 3600 O O   . ALA A 1 462 ? 112.049 88.727  63.140  1.00 145.67 ? 462 ALA A O   1 
ATOM 3601 C CB  . ALA A 1 462 ? 114.996 87.115  64.395  1.00 145.67 ? 462 ALA A CB  1 
ATOM 3602 N N   . GLU A 1 463 ? 112.422 86.544  63.566  1.00 139.94 ? 463 GLU A N   1 
ATOM 3603 C CA  . GLU A 1 463 ? 111.010 86.197  63.586  1.00 139.94 ? 463 GLU A CA  1 
ATOM 3604 C C   . GLU A 1 463 ? 110.280 86.977  64.681  1.00 139.94 ? 463 GLU A C   1 
ATOM 3605 O O   . GLU A 1 463 ? 110.865 87.306  65.717  1.00 139.94 ? 463 GLU A O   1 
ATOM 3606 C CB  . GLU A 1 463 ? 110.828 84.696  63.815  1.00 139.94 ? 463 GLU A CB  1 
ATOM 3607 C CG  . GLU A 1 463 ? 111.391 83.808  62.713  1.00 139.94 ? 463 GLU A CG  1 
ATOM 3608 C CD  . GLU A 1 463 ? 112.898 83.661  62.784  1.00 139.94 ? 463 GLU A CD  1 
ATOM 3609 O OE1 . GLU A 1 463 ? 113.486 84.049  63.816  1.00 139.94 ? 463 GLU A OE1 1 
ATOM 3610 O OE2 . GLU A 1 463 ? 113.493 83.161  61.807  1.00 139.94 ? 463 GLU A OE2 1 
ATOM 3611 N N   . PRO A 1 464 ? 109.001 87.298  64.465  1.00 136.08 ? 464 PRO A N   1 
ATOM 3612 C CA  . PRO A 1 464 ? 108.264 88.105  65.453  1.00 136.08 ? 464 PRO A CA  1 
ATOM 3613 C C   . PRO A 1 464 ? 108.185 87.482  66.835  1.00 136.08 ? 464 PRO A C   1 
ATOM 3614 O O   . PRO A 1 464 ? 108.171 88.223  67.825  1.00 136.08 ? 464 PRO A O   1 
ATOM 3615 C CB  . PRO A 1 464 ? 106.871 88.240  64.822  1.00 136.08 ? 464 PRO A CB  1 
ATOM 3616 C CG  . PRO A 1 464 ? 107.108 88.076  63.360  1.00 136.08 ? 464 PRO A CG  1 
ATOM 3617 C CD  . PRO A 1 464 ? 108.205 87.055  63.251  1.00 136.08 ? 464 PRO A CD  1 
ATOM 3618 N N   . ARG A 1 465 ? 108.123 86.151  66.939  1.00 131.30 ? 465 ARG A N   1 
ATOM 3619 C CA  . ARG A 1 465 ? 107.974 85.518  68.244  1.00 131.30 ? 465 ARG A CA  1 
ATOM 3620 C C   . ARG A 1 465 ? 109.137 85.827  69.179  1.00 131.30 ? 465 ARG A C   1 
ATOM 3621 O O   . ARG A 1 465 ? 108.932 85.901  70.395  1.00 131.30 ? 465 ARG A O   1 
ATOM 3622 C CB  . ARG A 1 465 ? 107.809 84.003  68.088  1.00 131.30 ? 465 ARG A CB  1 
ATOM 3623 C CG  . ARG A 1 465 ? 109.003 83.278  67.483  1.00 131.30 ? 465 ARG A CG  1 
ATOM 3624 C CD  . ARG A 1 465 ? 108.818 81.768  67.555  1.00 131.30 ? 465 ARG A CD  1 
ATOM 3625 N NE  . ARG A 1 465 ? 108.608 81.314  68.925  1.00 131.30 ? 465 ARG A NE  1 
ATOM 3626 C CZ  . ARG A 1 465 ? 108.326 80.064  69.269  1.00 131.30 ? 465 ARG A CZ  1 
ATOM 3627 N NH1 . ARG A 1 465 ? 108.212 79.106  68.363  1.00 131.30 ? 465 ARG A NH1 1 
ATOM 3628 N NH2 . ARG A 1 465 ? 108.150 79.769  70.554  1.00 131.30 ? 465 ARG A NH2 1 
ATOM 3629 N N   . VAL A 1 466 ? 110.344 86.016  68.645  1.00 119.71 ? 466 VAL A N   1 
ATOM 3630 C CA  . VAL A 1 466 ? 111.468 86.430  69.475  1.00 119.71 ? 466 VAL A CA  1 
ATOM 3631 C C   . VAL A 1 466 ? 111.617 87.948  69.516  1.00 119.71 ? 466 VAL A C   1 
ATOM 3632 O O   . VAL A 1 466 ? 112.242 88.476  70.448  1.00 119.71 ? 466 VAL A O   1 
ATOM 3633 C CB  . VAL A 1 466 ? 112.775 85.771  68.994  1.00 119.71 ? 466 VAL A CB  1 
ATOM 3634 C CG1 . VAL A 1 466 ? 113.317 86.474  67.757  1.00 119.71 ? 466 VAL A CG1 1 
ATOM 3635 C CG2 . VAL A 1 466 ? 113.810 85.749  70.110  1.00 119.71 ? 466 VAL A CG2 1 
ATOM 3636 N N   . ALA A 1 467 ? 111.058 88.665  68.539  1.00 121.36 ? 467 ALA A N   1 
ATOM 3637 C CA  . ALA A 1 467 ? 111.118 90.122  68.563  1.00 121.36 ? 467 ALA A CA  1 
ATOM 3638 C C   . ALA A 1 467 ? 110.223 90.693  69.655  1.00 121.36 ? 467 ALA A C   1 
ATOM 3639 O O   . ALA A 1 467 ? 110.560 91.707  70.276  1.00 121.36 ? 467 ALA A O   1 
ATOM 3640 C CB  . ALA A 1 467 ? 110.727 90.686  67.199  1.00 121.36 ? 467 ALA A CB  1 
ATOM 3641 N N   . SER A 1 468 ? 109.069 90.066  69.888  1.00 138.57 ? 468 SER A N   1 
ATOM 3642 C CA  . SER A 1 468 ? 108.171 90.537  70.936  1.00 138.57 ? 468 SER A CA  1 
ATOM 3643 C C   . SER A 1 468 ? 108.803 90.388  72.314  1.00 138.57 ? 468 SER A C   1 
ATOM 3644 O O   . SER A 1 468 ? 108.700 91.290  73.153  1.00 138.57 ? 468 SER A O   1 
ATOM 3645 C CB  . SER A 1 468 ? 106.843 89.781  70.868  1.00 138.57 ? 468 SER A CB  1 
ATOM 3646 O OG  . SER A 1 468 ? 106.221 89.951  69.605  1.00 138.57 ? 468 SER A OG  1 
ATOM 3647 N N   . ASN A 1 469 ? 109.464 89.256  72.564  1.00 119.68 ? 469 ASN A N   1 
ATOM 3648 C CA  . ASN A 1 469 ? 110.017 89.000  73.890  1.00 119.68 ? 469 ASN A CA  1 
ATOM 3649 C C   . ASN A 1 469 ? 111.188 89.926  74.196  1.00 119.68 ? 469 ASN A C   1 
ATOM 3650 O O   . ASN A 1 469 ? 111.466 90.221  75.364  1.00 119.68 ? 469 ASN A O   1 
ATOM 3651 C CB  . ASN A 1 469 ? 110.444 87.537  73.998  1.00 119.68 ? 469 ASN A CB  1 
ATOM 3652 C CG  . ASN A 1 469 ? 110.313 86.996  75.406  1.00 119.68 ? 469 ASN A CG  1 
ATOM 3653 O OD1 . ASN A 1 469 ? 110.468 87.729  76.383  1.00 119.68 ? 469 ASN A OD1 1 
ATOM 3654 N ND2 . ASN A 1 469 ? 110.022 85.706  75.518  1.00 119.68 ? 469 ASN A ND2 1 
ATOM 3655 N N   . VAL A 1 470 ? 111.888 90.397  73.161  1.00 113.09 ? 470 VAL A N   1 
ATOM 3656 C CA  . VAL A 1 470 ? 113.051 91.249  73.388  1.00 113.09 ? 470 VAL A CA  1 
ATOM 3657 C C   . VAL A 1 470 ? 112.664 92.717  73.519  1.00 113.09 ? 470 VAL A C   1 
ATOM 3658 O O   . VAL A 1 470 ? 113.424 93.500  74.103  1.00 113.09 ? 470 VAL A O   1 
ATOM 3659 C CB  . VAL A 1 470 ? 114.093 91.056  72.269  1.00 113.09 ? 470 VAL A CB  1 
ATOM 3660 C CG1 . VAL A 1 470 ? 113.629 91.690  70.970  1.00 113.09 ? 470 VAL A CG1 1 
ATOM 3661 C CG2 . VAL A 1 470 ? 115.451 91.606  72.689  1.00 113.09 ? 470 VAL A CG2 1 
ATOM 3662 N N   . CYS A 1 471 ? 111.504 93.113  72.990  1.00 123.00 ? 471 CYS A N   1 
ATOM 3663 C CA  . CYS A 1 471 ? 111.079 94.505  73.104  1.00 123.00 ? 471 CYS A CA  1 
ATOM 3664 C C   . CYS A 1 471 ? 110.870 94.907  74.558  1.00 123.00 ? 471 CYS A C   1 
ATOM 3665 O O   . CYS A 1 471 ? 111.293 95.993  74.971  1.00 123.00 ? 471 CYS A O   1 
ATOM 3666 C CB  . CYS A 1 471 ? 109.803 94.736  72.297  1.00 123.00 ? 471 CYS A CB  1 
ATOM 3667 S SG  . CYS A 1 471 ? 110.066 94.886  70.518  1.00 123.00 ? 471 CYS A SG  1 
ATOM 3668 N N   . TRP A 1 472 ? 110.213 94.053  75.348  1.00 131.41 ? 472 TRP A N   1 
ATOM 3669 C CA  . TRP A 1 472 ? 110.030 94.363  76.762  1.00 131.41 ? 472 TRP A CA  1 
ATOM 3670 C C   . TRP A 1 472 ? 111.359 94.410  77.499  1.00 131.41 ? 472 TRP A C   1 
ATOM 3671 O O   . TRP A 1 472 ? 111.494 95.143  78.486  1.00 131.41 ? 472 TRP A O   1 
ATOM 3672 C CB  . TRP A 1 472 ? 109.092 93.348  77.415  1.00 131.41 ? 472 TRP A CB  1 
ATOM 3673 C CG  . TRP A 1 472 ? 107.648 93.737  77.323  1.00 131.41 ? 472 TRP A CG  1 
ATOM 3674 C CD1 . TRP A 1 472 ? 106.990 94.638  78.110  1.00 131.41 ? 472 TRP A CD1 1 
ATOM 3675 C CD2 . TRP A 1 472 ? 106.681 93.239  76.391  1.00 131.41 ? 472 TRP A CD2 1 
ATOM 3676 N NE1 . TRP A 1 472 ? 105.675 94.730  77.726  1.00 131.41 ? 472 TRP A NE1 1 
ATOM 3677 C CE2 . TRP A 1 472 ? 105.460 93.882  76.672  1.00 131.41 ? 472 TRP A CE2 1 
ATOM 3678 C CE3 . TRP A 1 472 ? 106.730 92.311  75.347  1.00 131.41 ? 472 TRP A CE3 1 
ATOM 3679 C CZ2 . TRP A 1 472 ? 104.299 93.626  75.948  1.00 131.41 ? 472 TRP A CZ2 1 
ATOM 3680 C CZ3 . TRP A 1 472 ? 105.577 92.059  74.629  1.00 131.41 ? 472 TRP A CZ3 1 
ATOM 3681 C CH2 . TRP A 1 472 ? 104.378 92.714  74.932  1.00 131.41 ? 472 TRP A CH2 1 
ATOM 3682 N N   . ALA A 1 473 ? 112.344 93.632  77.046  1.00 111.15 ? 473 ALA A N   1 
ATOM 3683 C CA  . ALA A 1 473 ? 113.680 93.732  77.619  1.00 111.15 ? 473 ALA A CA  1 
ATOM 3684 C C   . ALA A 1 473 ? 114.272 95.113  77.378  1.00 111.15 ? 473 ALA A C   1 
ATOM 3685 O O   . ALA A 1 473 ? 114.899 95.693  78.272  1.00 111.15 ? 473 ALA A O   1 
ATOM 3686 C CB  . ALA A 1 473 ? 114.584 92.646  77.037  1.00 111.15 ? 473 ALA A CB  1 
ATOM 3687 N N   . PHE A 1 474 ? 114.084 95.657  76.173  1.00 107.38 ? 474 PHE A N   1 
ATOM 3688 C CA  . PHE A 1 474 ? 114.578 96.997  75.873  1.00 107.38 ? 474 PHE A CA  1 
ATOM 3689 C C   . PHE A 1 474 ? 113.929 98.039  76.777  1.00 107.38 ? 474 PHE A C   1 
ATOM 3690 O O   . PHE A 1 474 ? 114.607 98.924  77.312  1.00 107.38 ? 474 PHE A O   1 
ATOM 3691 C CB  . PHE A 1 474 ? 114.327 97.330  74.402  1.00 107.38 ? 474 PHE A CB  1 
ATOM 3692 C CG  . PHE A 1 474 ? 115.520 97.099  73.516  1.00 107.38 ? 474 PHE A CG  1 
ATOM 3693 C CD1 . PHE A 1 474 ? 116.801 97.088  74.043  1.00 107.38 ? 474 PHE A CD1 1 
ATOM 3694 C CD2 . PHE A 1 474 ? 115.360 96.897  72.156  1.00 107.38 ? 474 PHE A CD2 1 
ATOM 3695 C CE1 . PHE A 1 474 ? 117.899 96.879  73.229  1.00 107.38 ? 474 PHE A CE1 1 
ATOM 3696 C CE2 . PHE A 1 474 ? 116.455 96.687  71.337  1.00 107.38 ? 474 PHE A CE2 1 
ATOM 3697 C CZ  . PHE A 1 474 ? 117.725 96.679  71.874  1.00 107.38 ? 474 PHE A CZ  1 
ATOM 3698 N N   . SER A 1 475 ? 112.608 97.953  76.950  1.00 121.77 ? 475 SER A N   1 
ATOM 3699 C CA  . SER A 1 475 ? 111.913 98.907  77.807  1.00 121.77 ? 475 SER A CA  1 
ATOM 3700 C C   . SER A 1 475 ? 112.373 98.789  79.255  1.00 121.77 ? 475 SER A C   1 
ATOM 3701 O O   . SER A 1 475 ? 112.601 99.803  79.924  1.00 121.77 ? 475 SER A O   1 
ATOM 3702 C CB  . SER A 1 475 ? 110.402 98.702  77.705  1.00 121.77 ? 475 SER A CB  1 
ATOM 3703 O OG  . SER A 1 475 ? 110.031 97.407  78.144  1.00 121.77 ? 475 SER A OG  1 
ATOM 3704 N N   . SER A 1 476 ? 112.515 97.559  79.755  1.00 124.68 ? 476 SER A N   1 
ATOM 3705 C CA  . SER A 1 476 ? 112.980 97.367  81.125  1.00 124.68 ? 476 SER A CA  1 
ATOM 3706 C C   . SER A 1 476 ? 114.429 97.809  81.284  1.00 124.68 ? 476 SER A C   1 
ATOM 3707 O O   . SER A 1 476 ? 114.808 98.346  82.333  1.00 124.68 ? 476 SER A O   1 
ATOM 3708 C CB  . SER A 1 476 ? 112.818 95.905  81.535  1.00 124.68 ? 476 SER A CB  1 
ATOM 3709 O OG  . SER A 1 476 ? 113.294 95.692  82.852  1.00 124.68 ? 476 SER A OG  1 
ATOM 3710 N N   . LEU A 1 477 ? 115.257 97.579  80.262  1.00 122.16 ? 477 LEU A N   1 
ATOM 3711 C CA  . LEU A 1 477 ? 116.647 98.013  80.329  1.00 122.16 ? 477 LEU A CA  1 
ATOM 3712 C C   . LEU A 1 477 ? 116.737 99.524  80.485  1.00 122.16 ? 477 LEU A C   1 
ATOM 3713 O O   . LEU A 1 477 ? 117.561 100.027 81.258  1.00 122.16 ? 477 LEU A O   1 
ATOM 3714 C CB  . LEU A 1 477 ? 117.407 97.554  79.084  1.00 122.16 ? 477 LEU A CB  1 
ATOM 3715 C CG  . LEU A 1 477 ? 118.914 97.817  79.070  1.00 122.16 ? 477 LEU A CG  1 
ATOM 3716 C CD1 . LEU A 1 477 ? 119.593 97.090  80.220  1.00 122.16 ? 477 LEU A CD1 1 
ATOM 3717 C CD2 . LEU A 1 477 ? 119.528 97.408  77.738  1.00 122.16 ? 477 LEU A CD2 1 
ATOM 3718 N N   . ALA A 1 478 ? 115.895 100.262 79.760  1.00 138.93 ? 478 ALA A N   1 
ATOM 3719 C CA  . ALA A 1 478 ? 115.852 101.709 79.931  1.00 138.93 ? 478 ALA A CA  1 
ATOM 3720 C C   . ALA A 1 478 ? 115.425 102.083 81.344  1.00 138.93 ? 478 ALA A C   1 
ATOM 3721 O O   . ALA A 1 478 ? 116.017 102.978 81.959  1.00 138.93 ? 478 ALA A O   1 
ATOM 3722 C CB  . ALA A 1 478 ? 114.911 102.331 78.901  1.00 138.93 ? 478 ALA A CB  1 
ATOM 3723 N N   . GLU A 1 479 ? 114.398 101.414 81.874  1.00 148.71 ? 479 GLU A N   1 
ATOM 3724 C CA  . GLU A 1 479 ? 113.968 101.686 83.241  1.00 148.71 ? 479 GLU A CA  1 
ATOM 3725 C C   . GLU A 1 479 ? 115.054 101.314 84.242  1.00 148.71 ? 479 GLU A C   1 
ATOM 3726 O O   . GLU A 1 479 ? 115.280 102.038 85.218  1.00 148.71 ? 479 GLU A O   1 
ATOM 3727 C CB  . GLU A 1 479 ? 112.671 100.936 83.545  1.00 148.71 ? 479 GLU A CB  1 
ATOM 3728 C CG  . GLU A 1 479 ? 111.517 101.315 82.631  1.00 148.71 ? 479 GLU A CG  1 
ATOM 3729 C CD  . GLU A 1 479 ? 110.196 100.711 83.066  1.00 148.71 ? 479 GLU A CD  1 
ATOM 3730 O OE1 . GLU A 1 479 ? 110.159 100.059 84.130  1.00 148.71 ? 479 GLU A OE1 1 
ATOM 3731 O OE2 . GLU A 1 479 ? 109.193 100.890 82.343  1.00 148.71 ? 479 GLU A OE2 1 
ATOM 3732 N N   . ALA A 1 480 ? 115.731 100.187 84.019  1.00 155.58 ? 480 ALA A N   1 
ATOM 3733 C CA  . ALA A 1 480 ? 116.863 99.831  84.866  1.00 155.58 ? 480 ALA A CA  1 
ATOM 3734 C C   . ALA A 1 480 ? 117.973 100.867 84.753  1.00 155.58 ? 480 ALA A C   1 
ATOM 3735 O O   . ALA A 1 480 ? 118.616 101.209 85.753  1.00 155.58 ? 480 ALA A O   1 
ATOM 3736 C CB  . ALA A 1 480 ? 117.379 98.441  84.498  1.00 155.58 ? 480 ALA A CB  1 
ATOM 3737 N N   . ALA A 1 481 ? 118.216 101.369 83.541  1.00 166.99 ? 481 ALA A N   1 
ATOM 3738 C CA  . ALA A 1 481 ? 119.188 102.442 83.367  1.00 166.99 ? 481 ALA A CA  1 
ATOM 3739 C C   . ALA A 1 481 ? 118.755 103.704 84.102  1.00 166.99 ? 481 ALA A C   1 
ATOM 3740 O O   . ALA A 1 481 ? 119.576 104.361 84.750  1.00 166.99 ? 481 ALA A O   1 
ATOM 3741 C CB  . ALA A 1 481 ? 119.394 102.728 81.880  1.00 166.99 ? 481 ALA A CB  1 
ATOM 3742 N N   . TYR A 1 482 ? 117.468 104.054 84.016  1.00 173.00 ? 482 TYR A N   1 
ATOM 3743 C CA  . TYR A 1 482 ? 116.978 105.250 84.695  1.00 173.00 ? 482 TYR A CA  1 
ATOM 3744 C C   . TYR A 1 482 ? 117.135 105.129 86.206  1.00 173.00 ? 482 TYR A C   1 
ATOM 3745 O O   . TYR A 1 482 ? 117.540 106.088 86.874  1.00 173.00 ? 482 TYR A O   1 
ATOM 3746 C CB  . TYR A 1 482 ? 115.516 105.506 84.325  1.00 173.00 ? 482 TYR A CB  1 
ATOM 3747 C CG  . TYR A 1 482 ? 115.043 106.924 84.582  1.00 173.00 ? 482 TYR A CG  1 
ATOM 3748 C CD1 . TYR A 1 482 ? 115.922 107.906 85.022  1.00 173.00 ? 482 TYR A CD1 1 
ATOM 3749 C CD2 . TYR A 1 482 ? 113.715 107.278 84.384  1.00 173.00 ? 482 TYR A CD2 1 
ATOM 3750 C CE1 . TYR A 1 482 ? 115.493 109.199 85.259  1.00 173.00 ? 482 TYR A CE1 1 
ATOM 3751 C CE2 . TYR A 1 482 ? 113.276 108.570 84.617  1.00 173.00 ? 482 TYR A CE2 1 
ATOM 3752 C CZ  . TYR A 1 482 ? 114.169 109.526 85.055  1.00 173.00 ? 482 TYR A CZ  1 
ATOM 3753 O OH  . TYR A 1 482 ? 113.740 110.813 85.290  1.00 173.00 ? 482 TYR A OH  1 
ATOM 3754 N N   . GLU A 1 483 ? 116.813 103.959 86.764  1.00 189.89 ? 483 GLU A N   1 
ATOM 3755 C CA  . GLU A 1 483 ? 117.002 103.748 88.195  1.00 189.89 ? 483 GLU A CA  1 
ATOM 3756 C C   . GLU A 1 483 ? 118.467 103.890 88.587  1.00 189.89 ? 483 GLU A C   1 
ATOM 3757 O O   . GLU A 1 483 ? 118.772 104.275 89.721  1.00 189.89 ? 483 GLU A O   1 
ATOM 3758 C CB  . GLU A 1 483 ? 116.468 102.372 88.595  1.00 189.89 ? 483 GLU A CB  1 
ATOM 3759 C CG  . GLU A 1 483 ? 115.802 102.330 89.963  1.00 189.89 ? 483 GLU A CG  1 
ATOM 3760 C CD  . GLU A 1 483 ? 116.796 102.388 91.106  1.00 189.89 ? 483 GLU A CD  1 
ATOM 3761 O OE1 . GLU A 1 483 ? 117.907 101.839 90.958  1.00 189.89 ? 483 GLU A OE1 1 
ATOM 3762 O OE2 . GLU A 1 483 ? 116.466 102.985 92.153  1.00 189.89 ? 483 GLU A OE2 1 
ATOM 3763 N N   . ALA A 1 484 ? 119.382 103.583 87.669  1.00 191.92 ? 484 ALA A N   1 
ATOM 3764 C CA  . ALA A 1 484 ? 120.805 103.798 87.881  1.00 191.92 ? 484 ALA A CA  1 
ATOM 3765 C C   . ALA A 1 484 ? 121.281 105.167 87.407  1.00 191.92 ? 484 ALA A C   1 
ATOM 3766 O O   . ALA A 1 484 ? 122.387 105.580 87.772  1.00 191.92 ? 484 ALA A O   1 
ATOM 3767 C CB  . ALA A 1 484 ? 121.612 102.703 87.177  1.00 191.92 ? 484 ALA A CB  1 
ATOM 3768 N N   . ALA A 1 485 ? 120.483 105.874 86.606  1.00 195.37 ? 485 ALA A N   1 
ATOM 3769 C CA  . ALA A 1 485 ? 120.866 107.179 86.080  1.00 195.37 ? 485 ALA A CA  1 
ATOM 3770 C C   . ALA A 1 485 ? 120.601 108.324 87.045  1.00 195.37 ? 485 ALA A C   1 
ATOM 3771 O O   . ALA A 1 485 ? 121.438 109.226 87.159  1.00 195.37 ? 485 ALA A O   1 
ATOM 3772 C CB  . ALA A 1 485 ? 120.136 107.459 84.763  1.00 195.37 ? 485 ALA A CB  1 
ATOM 3773 N N   . ASP A 1 486 ? 119.459 108.317 87.735  1.00 211.83 ? 486 ASP A N   1 
ATOM 3774 C CA  . ASP A 1 486 ? 119.153 109.390 88.673  1.00 211.83 ? 486 ASP A CA  1 
ATOM 3775 C C   . ASP A 1 486 ? 120.119 109.418 89.850  1.00 211.83 ? 486 ASP A C   1 
ATOM 3776 O O   . ASP A 1 486 ? 120.401 110.498 90.377  1.00 211.83 ? 486 ASP A O   1 
ATOM 3777 C CB  . ASP A 1 486 ? 117.715 109.259 89.179  1.00 211.83 ? 486 ASP A CB  1 
ATOM 3778 C CG  . ASP A 1 486 ? 117.480 107.972 89.943  1.00 211.83 ? 486 ASP A CG  1 
ATOM 3779 O OD1 . ASP A 1 486 ? 118.161 106.971 89.642  1.00 211.83 ? 486 ASP A OD1 1 
ATOM 3780 O OD2 . ASP A 1 486 ? 116.611 107.961 90.839  1.00 211.83 ? 486 ASP A OD2 1 
ATOM 3781 N N   . VAL A 1 487 ? 120.615 108.261 90.278  1.00 217.75 ? 487 VAL A N   1 
ATOM 3782 C CA  . VAL A 1 487 ? 121.615 108.205 91.340  1.00 217.75 ? 487 VAL A CA  1 
ATOM 3783 C C   . VAL A 1 487 ? 122.934 108.830 90.899  1.00 217.75 ? 487 VAL A C   1 
ATOM 3784 O O   . VAL A 1 487 ? 123.540 109.605 91.643  1.00 217.75 ? 487 VAL A O   1 
ATOM 3785 C CB  . VAL A 1 487 ? 121.809 106.745 91.797  1.00 217.75 ? 487 VAL A CB  1 
ATOM 3786 C CG1 . VAL A 1 487 ? 122.825 106.669 92.930  1.00 217.75 ? 487 VAL A CG1 1 
ATOM 3787 C CG2 . VAL A 1 487 ? 120.478 106.144 92.224  1.00 217.75 ? 487 VAL A CG2 1 
ATOM 3788 N N   . ALA A 1 488 ? 123.395 108.504 89.690  1.00 211.67 ? 488 ALA A N   1 
ATOM 3789 C CA  . ALA A 1 488 ? 124.690 108.988 89.221  1.00 211.67 ? 488 ALA A CA  1 
ATOM 3790 C C   . ALA A 1 488 ? 124.567 110.335 88.514  1.00 211.67 ? 488 ALA A C   1 
ATOM 3791 O O   . ALA A 1 488 ? 125.225 111.310 88.892  1.00 211.67 ? 488 ALA A O   1 
ATOM 3792 C CB  . ALA A 1 488 ? 125.334 107.952 88.296  1.00 211.67 ? 488 ALA A CB  1 
ATOM 3793 N N   . ASP A 1 489 ? 123.734 110.403 87.478  1.00 202.08 ? 489 ASP A N   1 
ATOM 3794 C CA  . ASP A 1 489 ? 123.624 111.585 86.624  1.00 202.08 ? 489 ASP A CA  1 
ATOM 3795 C C   . ASP A 1 489 ? 122.547 112.504 87.192  1.00 202.08 ? 489 ASP A C   1 
ATOM 3796 O O   . ASP A 1 489 ? 121.357 112.185 87.146  1.00 202.08 ? 489 ASP A O   1 
ATOM 3797 C CB  . ASP A 1 489 ? 123.310 111.178 85.188  1.00 202.08 ? 489 ASP A CB  1 
ATOM 3798 C CG  . ASP A 1 489 ? 123.450 112.328 84.209  1.00 202.08 ? 489 ASP A CG  1 
ATOM 3799 O OD1 . ASP A 1 489 ? 123.852 113.433 84.630  1.00 202.08 ? 489 ASP A OD1 1 
ATOM 3800 O OD2 . ASP A 1 489 ? 123.158 112.123 83.012  1.00 202.08 ? 489 ASP A OD2 1 
ATOM 3801 N N   . ASP A 1 490 ? 122.977 113.649 87.731  1.00 212.33 ? 490 ASP A N   1 
ATOM 3802 C CA  . ASP A 1 490 ? 122.080 114.684 88.240  1.00 212.33 ? 490 ASP A CA  1 
ATOM 3803 C C   . ASP A 1 490 ? 121.182 114.143 89.348  1.00 212.33 ? 490 ASP A C   1 
ATOM 3804 O O   . ASP A 1 490 ? 121.431 113.058 89.883  1.00 212.33 ? 490 ASP A O   1 
ATOM 3805 C CB  . ASP A 1 490 ? 121.241 115.274 87.102  1.00 212.33 ? 490 ASP A CB  1 
ATOM 3806 C CG  . ASP A 1 490 ? 120.809 116.705 87.373  1.00 212.33 ? 490 ASP A CG  1 
ATOM 3807 O OD1 . ASP A 1 490 ? 121.682 117.599 87.383  1.00 212.33 ? 490 ASP A OD1 1 
ATOM 3808 O OD2 . ASP A 1 490 ? 119.598 116.935 87.575  1.00 212.33 ? 490 ASP A OD2 1 
ATOM 3809 N N   . GLN A 1 491 ? 120.149 114.899 89.714  1.00 216.98 ? 491 GLN A N   1 
ATOM 3810 C CA  . GLN A 1 491 ? 119.210 114.489 90.749  1.00 216.98 ? 491 GLN A CA  1 
ATOM 3811 C C   . GLN A 1 491 ? 117.753 114.540 90.316  1.00 216.98 ? 491 GLN A C   1 
ATOM 3812 O O   . GLN A 1 491 ? 116.944 113.776 90.849  1.00 216.98 ? 491 GLN A O   1 
ATOM 3813 C CB  . GLN A 1 491 ? 119.383 115.353 92.012  1.00 216.98 ? 491 GLN A CB  1 
ATOM 3814 C CG  . GLN A 1 491 ? 118.956 116.812 91.862  1.00 216.98 ? 491 GLN A CG  1 
ATOM 3815 C CD  . GLN A 1 491 ? 119.924 117.635 91.034  1.00 216.98 ? 491 GLN A CD  1 
ATOM 3816 O OE1 . GLN A 1 491 ? 121.042 117.204 90.753  1.00 216.98 ? 491 GLN A OE1 1 
ATOM 3817 N NE2 . GLN A 1 491 ? 119.496 118.827 90.636  1.00 216.98 ? 491 GLN A NE2 1 
ATOM 3818 N N   . GLU A 1 492 ? 117.393 115.414 89.376  1.00 208.08 ? 492 GLU A N   1 
ATOM 3819 C CA  . GLU A 1 492 ? 116.007 115.557 88.946  1.00 208.08 ? 492 GLU A CA  1 
ATOM 3820 C C   . GLU A 1 492 ? 115.760 115.098 87.516  1.00 208.08 ? 492 GLU A C   1 
ATOM 3821 O O   . GLU A 1 492 ? 114.620 114.762 87.178  1.00 208.08 ? 492 GLU A O   1 
ATOM 3822 C CB  . GLU A 1 492 ? 115.558 117.016 89.096  1.00 208.08 ? 492 GLU A CB  1 
ATOM 3823 C CG  . GLU A 1 492 ? 116.527 118.035 88.515  1.00 208.08 ? 492 GLU A CG  1 
ATOM 3824 C CD  . GLU A 1 492 ? 116.317 118.267 87.034  1.00 208.08 ? 492 GLU A CD  1 
ATOM 3825 O OE1 . GLU A 1 492 ? 115.182 118.064 86.553  1.00 208.08 ? 492 GLU A OE1 1 
ATOM 3826 O OE2 . GLU A 1 492 ? 117.288 118.653 86.350  1.00 208.08 ? 492 GLU A OE2 1 
ATOM 3827 N N   . GLU A 1 493 ? 116.792 115.071 86.668  1.00 200.07 ? 493 GLU A N   1 
ATOM 3828 C CA  . GLU A 1 493 ? 116.629 114.638 85.286  1.00 200.07 ? 493 GLU A CA  1 
ATOM 3829 C C   . GLU A 1 493 ? 117.991 114.267 84.730  1.00 200.07 ? 493 GLU A C   1 
ATOM 3830 O O   . GLU A 1 493 ? 118.927 115.072 84.838  1.00 200.07 ? 493 GLU A O   1 
ATOM 3831 C CB  . GLU A 1 493 ? 115.987 115.734 84.427  1.00 200.07 ? 493 GLU A CB  1 
ATOM 3832 C CG  . GLU A 1 493 ? 115.468 115.249 83.081  1.00 200.07 ? 493 GLU A CG  1 
ATOM 3833 C CD  . GLU A 1 493 ? 114.198 114.427 83.206  1.00 200.07 ? 493 GLU A CD  1 
ATOM 3834 O OE1 . GLU A 1 493 ? 113.542 114.496 84.267  1.00 200.07 ? 493 GLU A OE1 1 
ATOM 3835 O OE2 . GLU A 1 493 ? 113.854 113.713 82.241  1.00 200.07 ? 493 GLU A OE2 1 
ATOM 3836 N N   . PRO A 1 494 ? 118.147 113.083 84.141  1.00 182.57 ? 494 PRO A N   1 
ATOM 3837 C CA  . PRO A 1 494 ? 119.461 112.683 83.627  1.00 182.57 ? 494 PRO A CA  1 
ATOM 3838 C C   . PRO A 1 494 ? 119.895 113.534 82.444  1.00 182.57 ? 494 PRO A C   1 
ATOM 3839 O O   . PRO A 1 494 ? 119.075 114.032 81.668  1.00 182.57 ? 494 PRO A O   1 
ATOM 3840 C CB  . PRO A 1 494 ? 119.250 111.223 83.211  1.00 182.57 ? 494 PRO A CB  1 
ATOM 3841 C CG  . PRO A 1 494 ? 117.787 111.123 82.935  1.00 182.57 ? 494 PRO A CG  1 
ATOM 3842 C CD  . PRO A 1 494 ? 117.124 112.049 83.915  1.00 182.57 ? 494 PRO A CD  1 
ATOM 3843 N N   . ALA A 1 495 ? 121.211 113.696 82.315  1.00 179.00 ? 495 ALA A N   1 
ATOM 3844 C CA  . ALA A 1 495 ? 121.814 114.445 81.220  1.00 179.00 ? 495 ALA A CA  1 
ATOM 3845 C C   . ALA A 1 495 ? 122.470 113.546 80.183  1.00 179.00 ? 495 ALA A C   1 
ATOM 3846 O O   . ALA A 1 495 ? 122.297 113.763 78.980  1.00 179.00 ? 495 ALA A O   1 
ATOM 3847 C CB  . ALA A 1 495 ? 122.842 115.445 81.770  1.00 179.00 ? 495 ALA A CB  1 
ATOM 3848 N N   . THR A 1 496 ? 123.228 112.541 80.619  1.00 189.78 ? 496 THR A N   1 
ATOM 3849 C CA  . THR A 1 496 ? 123.878 111.601 79.706  1.00 189.78 ? 496 THR A CA  1 
ATOM 3850 C C   . THR A 1 496 ? 124.254 110.357 80.493  1.00 189.78 ? 496 THR A C   1 
ATOM 3851 O O   . THR A 1 496 ? 124.966 110.457 81.497  1.00 189.78 ? 496 THR A O   1 
ATOM 3852 C CB  . THR A 1 496 ? 125.121 112.220 79.058  1.00 189.78 ? 496 THR A CB  1 
ATOM 3853 O OG1 . THR A 1 496 ? 124.747 113.367 78.285  1.00 189.78 ? 496 THR A OG1 1 
ATOM 3854 C CG2 . THR A 1 496 ? 125.805 111.210 78.151  1.00 189.78 ? 496 THR A CG2 1 
ATOM 3855 N N   . TYR A 1 497 ? 123.789 109.192 80.046  1.00 180.71 ? 497 TYR A N   1 
ATOM 3856 C CA  . TYR A 1 497 ? 124.060 107.936 80.733  1.00 180.71 ? 497 TYR A CA  1 
ATOM 3857 C C   . TYR A 1 497 ? 124.571 106.902 79.733  1.00 180.71 ? 497 TYR A C   1 
ATOM 3858 O O   . TYR A 1 497 ? 124.905 107.221 78.587  1.00 180.71 ? 497 TYR A O   1 
ATOM 3859 C CB  . TYR A 1 497 ? 122.817 107.430 81.476  1.00 180.71 ? 497 TYR A CB  1 
ATOM 3860 C CG  . TYR A 1 497 ? 123.150 106.626 82.713  1.00 180.71 ? 497 TYR A CG  1 
ATOM 3861 C CD1 . TYR A 1 497 ? 123.870 107.193 83.758  1.00 180.71 ? 497 TYR A CD1 1 
ATOM 3862 C CD2 . TYR A 1 497 ? 122.746 105.303 82.839  1.00 180.71 ? 497 TYR A CD2 1 
ATOM 3863 C CE1 . TYR A 1 497 ? 124.182 106.466 84.889  1.00 180.71 ? 497 TYR A CE1 1 
ATOM 3864 C CE2 . TYR A 1 497 ? 123.052 104.567 83.969  1.00 180.71 ? 497 TYR A CE2 1 
ATOM 3865 C CZ  . TYR A 1 497 ? 123.770 105.155 84.991  1.00 180.71 ? 497 TYR A CZ  1 
ATOM 3866 O OH  . TYR A 1 497 ? 124.080 104.432 86.119  1.00 180.71 ? 497 TYR A OH  1 
ATOM 3867 N N   . CYS A 1 498 ? 124.642 105.648 80.189  1.00 169.89 ? 498 CYS A N   1 
ATOM 3868 C CA  . CYS A 1 498 ? 125.269 104.589 79.401  1.00 169.89 ? 498 CYS A CA  1 
ATOM 3869 C C   . CYS A 1 498 ? 124.519 104.326 78.099  1.00 169.89 ? 498 CYS A C   1 
ATOM 3870 O O   . CYS A 1 498 ? 125.131 104.278 77.026  1.00 169.89 ? 498 CYS A O   1 
ATOM 3871 C CB  . CYS A 1 498 ? 125.363 103.308 80.229  1.00 169.89 ? 498 CYS A CB  1 
ATOM 3872 S SG  . CYS A 1 498 ? 123.769 102.638 80.761  1.00 169.89 ? 498 CYS A SG  1 
ATOM 3873 N N   . LEU A 1 499 ? 123.198 104.146 78.171  1.00 158.26 ? 499 LEU A N   1 
ATOM 3874 C CA  . LEU A 1 499 ? 122.431 103.818 76.973  1.00 158.26 ? 499 LEU A CA  1 
ATOM 3875 C C   . LEU A 1 499 ? 122.371 104.977 75.985  1.00 158.26 ? 499 LEU A C   1 
ATOM 3876 O O   . LEU A 1 499 ? 122.004 104.766 74.824  1.00 158.26 ? 499 LEU A O   1 
ATOM 3877 C CB  . LEU A 1 499 ? 121.015 103.380 77.359  1.00 158.26 ? 499 LEU A CB  1 
ATOM 3878 C CG  . LEU A 1 499 ? 120.175 102.689 76.280  1.00 158.26 ? 499 LEU A CG  1 
ATOM 3879 C CD1 . LEU A 1 499 ? 120.903 101.482 75.719  1.00 158.26 ? 499 LEU A CD1 1 
ATOM 3880 C CD2 . LEU A 1 499 ? 118.815 102.285 76.830  1.00 158.26 ? 499 LEU A CD2 1 
ATOM 3881 N N   . SER A 1 500 ? 122.737 106.189 76.412  1.00 162.39 ? 500 SER A N   1 
ATOM 3882 C CA  . SER A 1 500 ? 122.691 107.350 75.530  1.00 162.39 ? 500 SER A CA  1 
ATOM 3883 C C   . SER A 1 500 ? 123.600 107.206 74.315  1.00 162.39 ? 500 SER A C   1 
ATOM 3884 O O   . SER A 1 500 ? 123.306 107.791 73.268  1.00 162.39 ? 500 SER A O   1 
ATOM 3885 C CB  . SER A 1 500 ? 123.061 108.615 76.304  1.00 162.39 ? 500 SER A CB  1 
ATOM 3886 O OG  . SER A 1 500 ? 122.160 108.841 77.375  1.00 162.39 ? 500 SER A OG  1 
ATOM 3887 N N   . SER A 1 501 ? 124.698 106.455 74.433  1.00 156.71 ? 501 SER A N   1 
ATOM 3888 C CA  . SER A 1 501 ? 125.592 106.268 73.295  1.00 156.71 ? 501 SER A CA  1 
ATOM 3889 C C   . SER A 1 501 ? 124.883 105.569 72.141  1.00 156.71 ? 501 SER A C   1 
ATOM 3890 O O   . SER A 1 501 ? 125.027 105.971 70.980  1.00 156.71 ? 501 SER A O   1 
ATOM 3891 C CB  . SER A 1 501 ? 126.828 105.479 73.726  1.00 156.71 ? 501 SER A CB  1 
ATOM 3892 O OG  . SER A 1 501 ? 127.552 106.172 74.728  1.00 156.71 ? 501 SER A OG  1 
ATOM 3893 N N   . SER A 1 502 ? 124.121 104.518 72.438  1.00 145.21 ? 502 SER A N   1 
ATOM 3894 C CA  . SER A 1 502 ? 123.353 103.789 71.439  1.00 145.21 ? 502 SER A CA  1 
ATOM 3895 C C   . SER A 1 502 ? 121.872 104.157 71.453  1.00 145.21 ? 502 SER A C   1 
ATOM 3896 O O   . SER A 1 502 ? 121.070 103.475 70.807  1.00 145.21 ? 502 SER A O   1 
ATOM 3897 C CB  . SER A 1 502 ? 123.528 102.283 71.640  1.00 145.21 ? 502 SER A CB  1 
ATOM 3898 O OG  . SER A 1 502 ? 124.894 101.914 71.548  1.00 145.21 ? 502 SER A OG  1 
ATOM 3899 N N   . PHE A 1 503 ? 121.493 105.208 72.187  1.00 137.42 ? 503 PHE A N   1 
ATOM 3900 C CA  . PHE A 1 503 ? 120.088 105.597 72.278  1.00 137.42 ? 503 PHE A CA  1 
ATOM 3901 C C   . PHE A 1 503 ? 119.521 105.981 70.917  1.00 137.42 ? 503 PHE A C   1 
ATOM 3902 O O   . PHE A 1 503 ? 118.449 105.503 70.529  1.00 137.42 ? 503 PHE A O   1 
ATOM 3903 C CB  . PHE A 1 503 ? 119.931 106.751 73.269  1.00 137.42 ? 503 PHE A CB  1 
ATOM 3904 C CG  . PHE A 1 503 ? 118.529 107.286 73.367  1.00 137.42 ? 503 PHE A CG  1 
ATOM 3905 C CD1 . PHE A 1 503 ? 117.588 106.664 74.169  1.00 137.42 ? 503 PHE A CD1 1 
ATOM 3906 C CD2 . PHE A 1 503 ? 118.157 108.422 72.667  1.00 137.42 ? 503 PHE A CD2 1 
ATOM 3907 C CE1 . PHE A 1 503 ? 116.300 107.160 74.263  1.00 137.42 ? 503 PHE A CE1 1 
ATOM 3908 C CE2 . PHE A 1 503 ? 116.871 108.921 72.757  1.00 137.42 ? 503 PHE A CE2 1 
ATOM 3909 C CZ  . PHE A 1 503 ? 115.942 108.289 73.556  1.00 137.42 ? 503 PHE A CZ  1 
ATOM 3910 N N   . GLU A 1 504 ? 120.217 106.851 70.181  1.00 134.15 ? 504 GLU A N   1 
ATOM 3911 C CA  . GLU A 1 504 ? 119.708 107.294 68.889  1.00 134.15 ? 504 GLU A CA  1 
ATOM 3912 C C   . GLU A 1 504 ? 119.668 106.168 67.864  1.00 134.15 ? 504 GLU A C   1 
ATOM 3913 O O   . GLU A 1 504 ? 118.854 106.222 66.936  1.00 134.15 ? 504 GLU A O   1 
ATOM 3914 C CB  . GLU A 1 504 ? 120.547 108.460 68.362  1.00 134.15 ? 504 GLU A CB  1 
ATOM 3915 C CG  . GLU A 1 504 ? 122.006 108.123 68.107  1.00 134.15 ? 504 GLU A CG  1 
ATOM 3916 C CD  . GLU A 1 504 ? 122.798 109.313 67.601  1.00 134.15 ? 504 GLU A CD  1 
ATOM 3917 O OE1 . GLU A 1 504 ? 122.230 110.424 67.536  1.00 134.15 ? 504 GLU A OE1 1 
ATOM 3918 O OE2 . GLU A 1 504 ? 123.989 109.139 67.270  1.00 134.15 ? 504 GLU A OE2 1 
ATOM 3919 N N   . LEU A 1 505 ? 120.524 105.154 68.007  1.00 125.79 ? 505 LEU A N   1 
ATOM 3920 C CA  . LEU A 1 505 ? 120.489 104.024 67.086  1.00 125.79 ? 505 LEU A CA  1 
ATOM 3921 C C   . LEU A 1 505 ? 119.277 103.137 67.345  1.00 125.79 ? 505 LEU A C   1 
ATOM 3922 O O   . LEU A 1 505 ? 118.585 102.723 66.407  1.00 125.79 ? 505 LEU A O   1 
ATOM 3923 C CB  . LEU A 1 505 ? 121.781 103.214 67.202  1.00 125.79 ? 505 LEU A CB  1 
ATOM 3924 C CG  . LEU A 1 505 ? 121.893 101.961 66.331  1.00 125.79 ? 505 LEU A CG  1 
ATOM 3925 C CD1 . LEU A 1 505 ? 121.917 102.324 64.855  1.00 125.79 ? 505 LEU A CD1 1 
ATOM 3926 C CD2 . LEU A 1 505 ? 123.127 101.156 66.708  1.00 125.79 ? 505 LEU A CD2 1 
ATOM 3927 N N   . ILE A 1 506 ? 119.008 102.828 68.615  1.00 122.91 ? 506 ILE A N   1 
ATOM 3928 C CA  . ILE A 1 506 ? 117.930 101.901 68.946  1.00 122.91 ? 506 ILE A CA  1 
ATOM 3929 C C   . ILE A 1 506 ? 116.546 102.512 68.769  1.00 122.91 ? 506 ILE A C   1 
ATOM 3930 O O   . ILE A 1 506 ? 115.604 101.789 68.419  1.00 122.91 ? 506 ILE A O   1 
ATOM 3931 C CB  . ILE A 1 506 ? 118.079 101.364 70.380  1.00 122.91 ? 506 ILE A CB  1 
ATOM 3932 C CG1 . ILE A 1 506 ? 118.067 102.503 71.399  1.00 122.91 ? 506 ILE A CG1 1 
ATOM 3933 C CG2 . ILE A 1 506 ? 119.357 100.560 70.515  1.00 122.91 ? 506 ILE A CG2 1 
ATOM 3934 C CD1 . ILE A 1 506 ? 118.155 102.031 72.832  1.00 122.91 ? 506 ILE A CD1 1 
ATOM 3935 N N   . VAL A 1 507 ? 116.386 103.816 69.010  1.00 131.24 ? 507 VAL A N   1 
ATOM 3936 C CA  . VAL A 1 507 ? 115.054 104.410 68.958  1.00 131.24 ? 507 VAL A CA  1 
ATOM 3937 C C   . VAL A 1 507 ? 114.499 104.365 67.538  1.00 131.24 ? 507 VAL A C   1 
ATOM 3938 O O   . VAL A 1 507 ? 113.327 104.030 67.330  1.00 131.24 ? 507 VAL A O   1 
ATOM 3939 C CB  . VAL A 1 507 ? 115.071 105.842 69.531  1.00 131.24 ? 507 VAL A CB  1 
ATOM 3940 C CG1 . VAL A 1 507 ? 116.033 106.736 68.767  1.00 131.24 ? 507 VAL A CG1 1 
ATOM 3941 C CG2 . VAL A 1 507 ? 113.667 106.433 69.530  1.00 131.24 ? 507 VAL A CG2 1 
ATOM 3942 N N   . GLN A 1 508 ? 115.326 104.684 66.539  1.00 129.67 ? 508 GLN A N   1 
ATOM 3943 C CA  . GLN A 1 508 ? 114.868 104.624 65.155  1.00 129.67 ? 508 GLN A CA  1 
ATOM 3944 C C   . GLN A 1 508 ? 114.666 103.189 64.688  1.00 129.67 ? 508 GLN A C   1 
ATOM 3945 O O   . GLN A 1 508 ? 113.841 102.941 63.800  1.00 129.67 ? 508 GLN A O   1 
ATOM 3946 C CB  . GLN A 1 508 ? 115.852 105.355 64.240  1.00 129.67 ? 508 GLN A CB  1 
ATOM 3947 C CG  . GLN A 1 508 ? 117.305 104.930 64.393  1.00 129.67 ? 508 GLN A CG  1 
ATOM 3948 C CD  . GLN A 1 508 ? 117.663 103.743 63.523  1.00 129.67 ? 508 GLN A CD  1 
ATOM 3949 O OE1 . GLN A 1 508 ? 116.962 103.432 62.561  1.00 129.67 ? 508 GLN A OE1 1 
ATOM 3950 N NE2 . GLN A 1 508 ? 118.759 103.073 63.857  1.00 129.67 ? 508 GLN A NE2 1 
ATOM 3951 N N   . LYS A 1 509 ? 115.408 102.240 65.260  1.00 132.47 ? 509 LYS A N   1 
ATOM 3952 C CA  . LYS A 1 509 ? 115.140 100.834 64.988  1.00 132.47 ? 509 LYS A CA  1 
ATOM 3953 C C   . LYS A 1 509 ? 113.762 100.432 65.494  1.00 132.47 ? 509 LYS A C   1 
ATOM 3954 O O   . LYS A 1 509 ? 113.051 99.664  64.835  1.00 132.47 ? 509 LYS A O   1 
ATOM 3955 C CB  . LYS A 1 509 ? 116.224 99.959  65.614  1.00 132.47 ? 509 LYS A CB  1 
ATOM 3956 C CG  . LYS A 1 509 ? 117.471 99.818  64.756  1.00 132.47 ? 509 LYS A CG  1 
ATOM 3957 C CD  . LYS A 1 509 ? 117.155 99.141  63.428  1.00 132.47 ? 509 LYS A CD  1 
ATOM 3958 C CE  . LYS A 1 509 ? 118.413 98.931  62.599  1.00 132.47 ? 509 LYS A CE  1 
ATOM 3959 N NZ  . LYS A 1 509 ? 118.120 98.232  61.315  1.00 132.47 ? 509 LYS A NZ  1 
ATOM 3960 N N   . LEU A 1 510 ? 113.372 100.933 66.669  1.00 123.65 ? 510 LEU A N   1 
ATOM 3961 C CA  . LEU A 1 510 ? 112.018 100.698 67.157  1.00 123.65 ? 510 LEU A CA  1 
ATOM 3962 C C   . LEU A 1 510 ? 110.986 101.327 66.230  1.00 123.65 ? 510 LEU A C   1 
ATOM 3963 O O   . LEU A 1 510 ? 109.887 100.789 66.058  1.00 123.65 ? 510 LEU A O   1 
ATOM 3964 C CB  . LEU A 1 510 ? 111.868 101.237 68.579  1.00 123.65 ? 510 LEU A CB  1 
ATOM 3965 C CG  . LEU A 1 510 ? 112.699 100.522 69.646  1.00 123.65 ? 510 LEU A CG  1 
ATOM 3966 C CD1 . LEU A 1 510 ? 112.397 101.075 71.031  1.00 123.65 ? 510 LEU A CD1 1 
ATOM 3967 C CD2 . LEU A 1 510 ? 112.461 99.022  69.601  1.00 123.65 ? 510 LEU A CD2 1 
ATOM 3968 N N   . LEU A 1 511 ? 111.318 102.472 65.630  1.00 136.97 ? 511 LEU A N   1 
ATOM 3969 C CA  . LEU A 1 511 ? 110.460 103.033 64.592  1.00 136.97 ? 511 LEU A CA  1 
ATOM 3970 C C   . LEU A 1 511 ? 110.405 102.116 63.377  1.00 136.97 ? 511 LEU A C   1 
ATOM 3971 O O   . LEU A 1 511 ? 109.349 101.964 62.750  1.00 136.97 ? 511 LEU A O   1 
ATOM 3972 C CB  . LEU A 1 511 ? 110.950 104.425 64.195  1.00 136.97 ? 511 LEU A CB  1 
ATOM 3973 C CG  . LEU A 1 511 ? 110.361 105.633 64.931  1.00 136.97 ? 511 LEU A CG  1 
ATOM 3974 C CD1 . LEU A 1 511 ? 108.856 105.699 64.732  1.00 136.97 ? 511 LEU A CD1 1 
ATOM 3975 C CD2 . LEU A 1 511 ? 110.706 105.616 66.411  1.00 136.97 ? 511 LEU A CD2 1 
ATOM 3976 N N   . GLU A 1 512 ? 111.535 101.498 63.026  1.00 139.17 ? 512 GLU A N   1 
ATOM 3977 C CA  . GLU A 1 512 ? 111.570 100.603 61.873  1.00 139.17 ? 512 GLU A CA  1 
ATOM 3978 C C   . GLU A 1 512 ? 110.716 99.363  62.105  1.00 139.17 ? 512 GLU A C   1 
ATOM 3979 O O   . GLU A 1 512 ? 109.917 98.978  61.243  1.00 139.17 ? 512 GLU A O   1 
ATOM 3980 C CB  . GLU A 1 512 ? 113.014 100.208 61.559  1.00 139.17 ? 512 GLU A CB  1 
ATOM 3981 C CG  . GLU A 1 512 ? 113.814 101.277 60.835  1.00 139.17 ? 512 GLU A CG  1 
ATOM 3982 C CD  . GLU A 1 512 ? 113.469 101.368 59.361  1.00 139.17 ? 512 GLU A CD  1 
ATOM 3983 O OE1 . GLU A 1 512 ? 112.725 100.497 58.863  1.00 139.17 ? 512 GLU A OE1 1 
ATOM 3984 O OE2 . GLU A 1 512 ? 113.947 102.312 58.698  1.00 139.17 ? 512 GLU A OE2 1 
ATOM 3985 N N   . THR A 1 513 ? 110.875 98.717  63.263  1.00 135.20 ? 513 THR A N   1 
ATOM 3986 C CA  . THR A 1 513 ? 110.151 97.480  63.535  1.00 135.20 ? 513 THR A CA  1 
ATOM 3987 C C   . THR A 1 513 ? 108.644 97.683  63.630  1.00 135.20 ? 513 THR A C   1 
ATOM 3988 O O   . THR A 1 513 ? 107.896 96.728  63.397  1.00 135.20 ? 513 THR A O   1 
ATOM 3989 C CB  . THR A 1 513 ? 110.675 96.823  64.817  1.00 135.20 ? 513 THR A CB  1 
ATOM 3990 O OG1 . THR A 1 513 ? 110.091 95.523  64.961  1.00 135.20 ? 513 THR A OG1 1 
ATOM 3991 C CG2 . THR A 1 513 ? 110.335 97.657  66.037  1.00 135.20 ? 513 THR A CG2 1 
ATOM 3992 N N   . THR A 1 514 ? 108.179 98.889  63.969  1.00 137.23 ? 514 THR A N   1 
ATOM 3993 C CA  . THR A 1 514 ? 106.751 99.180  63.935  1.00 137.23 ? 514 THR A CA  1 
ATOM 3994 C C   . THR A 1 514 ? 106.190 99.197  62.520  1.00 137.23 ? 514 THR A C   1 
ATOM 3995 O O   . THR A 1 514 ? 104.973 99.070  62.348  1.00 137.23 ? 514 THR A O   1 
ATOM 3996 C CB  . THR A 1 514 ? 106.461 100.523 64.610  1.00 137.23 ? 514 THR A CB  1 
ATOM 3997 O OG1 . THR A 1 514 ? 107.484 101.466 64.267  1.00 137.23 ? 514 THR A OG1 1 
ATOM 3998 C CG2 . THR A 1 514 ? 106.408 100.363 66.117  1.00 137.23 ? 514 THR A CG2 1 
ATOM 3999 N N   . ASP A 1 515 ? 107.043 99.355  61.511  1.00 151.03 ? 515 ASP A N   1 
ATOM 4000 C CA  . ASP A 1 515 ? 106.622 99.380  60.118  1.00 151.03 ? 515 ASP A CA  1 
ATOM 4001 C C   . ASP A 1 515 ? 106.595 97.993  59.488  1.00 151.03 ? 515 ASP A C   1 
ATOM 4002 O O   . ASP A 1 515 ? 106.184 97.859  58.331  1.00 151.03 ? 515 ASP A O   1 
ATOM 4003 C CB  . ASP A 1 515 ? 107.542 100.299 59.311  1.00 151.03 ? 515 ASP A CB  1 
ATOM 4004 C CG  . ASP A 1 515 ? 107.789 101.625 60.002  1.00 151.03 ? 515 ASP A CG  1 
ATOM 4005 O OD1 . ASP A 1 515 ? 106.919 102.058 60.787  1.00 151.03 ? 515 ASP A OD1 1 
ATOM 4006 O OD2 . ASP A 1 515 ? 108.853 102.233 59.763  1.00 151.03 ? 515 ASP A OD2 1 
ATOM 4007 N N   . ARG A 1 516 ? 107.026 96.969  60.218  1.00 151.48 ? 516 ARG A N   1 
ATOM 4008 C CA  . ARG A 1 516 ? 107.063 95.622  59.670  1.00 151.48 ? 516 ARG A CA  1 
ATOM 4009 C C   . ARG A 1 516 ? 105.647 95.119  59.399  1.00 151.48 ? 516 ARG A C   1 
ATOM 4010 O O   . ARG A 1 516 ? 104.743 95.335  60.213  1.00 151.48 ? 516 ARG A O   1 
ATOM 4011 C CB  . ARG A 1 516 ? 107.785 94.674  60.628  1.00 151.48 ? 516 ARG A CB  1 
ATOM 4012 C CG  . ARG A 1 516 ? 109.240 95.041  60.868  1.00 151.48 ? 516 ARG A CG  1 
ATOM 4013 C CD  . ARG A 1 516 ? 109.895 94.123  61.888  1.00 151.48 ? 516 ARG A CD  1 
ATOM 4014 N NE  . ARG A 1 516 ? 109.985 92.744  61.423  1.00 151.48 ? 516 ARG A NE  1 
ATOM 4015 C CZ  . ARG A 1 516 ? 110.561 91.761  62.101  1.00 151.48 ? 516 ARG A CZ  1 
ATOM 4016 N NH1 . ARG A 1 516 ? 111.114 91.969  63.285  1.00 151.48 ? 516 ARG A NH1 1 
ATOM 4017 N NH2 . ARG A 1 516 ? 110.584 90.538  61.578  1.00 151.48 ? 516 ARG A NH2 1 
ATOM 4018 N N   . PRO A 1 517 ? 105.421 94.453  58.262  1.00 155.53 ? 517 PRO A N   1 
ATOM 4019 C CA  . PRO A 1 517 ? 104.063 93.981  57.944  1.00 155.53 ? 517 PRO A CA  1 
ATOM 4020 C C   . PRO A 1 517 ? 103.525 92.949  58.919  1.00 155.53 ? 517 PRO A C   1 
ATOM 4021 O O   . PRO A 1 517 ? 102.302 92.787  59.003  1.00 155.53 ? 517 PRO A O   1 
ATOM 4022 C CB  . PRO A 1 517 ? 104.218 93.390  56.537  1.00 155.53 ? 517 PRO A CB  1 
ATOM 4023 C CG  . PRO A 1 517 ? 105.663 93.024  56.440  1.00 155.53 ? 517 PRO A CG  1 
ATOM 4024 C CD  . PRO A 1 517 ? 106.400 94.064  57.234  1.00 155.53 ? 517 PRO A CD  1 
ATOM 4025 N N   . ASP A 1 518 ? 104.388 92.249  59.656  1.00 153.14 ? 518 ASP A N   1 
ATOM 4026 C CA  . ASP A 1 518 ? 103.961 91.239  60.616  1.00 153.14 ? 518 ASP A CA  1 
ATOM 4027 C C   . ASP A 1 518 ? 103.819 91.805  62.026  1.00 153.14 ? 518 ASP A C   1 
ATOM 4028 O O   . ASP A 1 518 ? 104.033 91.087  63.009  1.00 153.14 ? 518 ASP A O   1 
ATOM 4029 C CB  . ASP A 1 518 ? 104.926 90.052  60.607  1.00 153.14 ? 518 ASP A CB  1 
ATOM 4030 C CG  . ASP A 1 518 ? 106.377 90.478  60.705  1.00 153.14 ? 518 ASP A CG  1 
ATOM 4031 O OD1 . ASP A 1 518 ? 106.634 91.674  60.947  1.00 153.14 ? 518 ASP A OD1 1 
ATOM 4032 O OD2 . ASP A 1 518 ? 107.263 89.614  60.531  1.00 153.14 ? 518 ASP A OD2 1 
ATOM 4033 N N   . GLY A 1 519 ? 103.467 93.087  62.142  1.00 147.60 ? 519 GLY A N   1 
ATOM 4034 C CA  . GLY A 1 519 ? 103.274 93.695  63.446  1.00 147.60 ? 519 GLY A CA  1 
ATOM 4035 C C   . GLY A 1 519 ? 102.122 93.113  64.240  1.00 147.60 ? 519 GLY A C   1 
ATOM 4036 O O   . GLY A 1 519 ? 102.107 93.235  65.469  1.00 147.60 ? 519 GLY A O   1 
ATOM 4037 N N   . HIS A 1 520 ? 101.155 92.486  63.568  1.00 159.89 ? 520 HIS A N   1 
ATOM 4038 C CA  . HIS A 1 520 ? 100.040 91.878  64.287  1.00 159.89 ? 520 HIS A CA  1 
ATOM 4039 C C   . HIS A 1 520 ? 100.457 90.589  64.984  1.00 159.89 ? 520 HIS A C   1 
ATOM 4040 O O   . HIS A 1 520 ? 99.905  90.251  66.038  1.00 159.89 ? 520 HIS A O   1 
ATOM 4041 C CB  . HIS A 1 520 ? 98.875  91.612  63.333  1.00 159.89 ? 520 HIS A CB  1 
ATOM 4042 C CG  . HIS A 1 520 ? 99.151  90.543  62.321  1.00 159.89 ? 520 HIS A CG  1 
ATOM 4043 N ND1 . HIS A 1 520 ? 98.266  89.519  62.061  1.00 159.89 ? 520 HIS A ND1 1 
ATOM 4044 C CD2 . HIS A 1 520 ? 100.211 90.341  61.502  1.00 159.89 ? 520 HIS A CD2 1 
ATOM 4045 C CE1 . HIS A 1 520 ? 98.771  88.730  61.129  1.00 159.89 ? 520 HIS A CE1 1 
ATOM 4046 N NE2 . HIS A 1 520 ? 99.950  89.207  60.772  1.00 159.89 ? 520 HIS A NE2 1 
ATOM 4047 N N   . GLN A 1 521 ? 101.415 89.860  64.414  1.00 147.81 ? 521 GLN A N   1 
ATOM 4048 C CA  . GLN A 1 521 ? 101.847 88.586  64.973  1.00 147.81 ? 521 GLN A CA  1 
ATOM 4049 C C   . GLN A 1 521 ? 102.509 88.797  66.329  1.00 147.81 ? 521 GLN A C   1 
ATOM 4050 O O   . GLN A 1 521 ? 103.437 89.603  66.458  1.00 147.81 ? 521 GLN A O   1 
ATOM 4051 C CB  . GLN A 1 521 ? 102.812 87.890  64.013  1.00 147.81 ? 521 GLN A CB  1 
ATOM 4052 C CG  . GLN A 1 521 ? 103.306 86.538  64.494  1.00 147.81 ? 521 GLN A CG  1 
ATOM 4053 C CD  . GLN A 1 521 ? 104.285 85.900  63.528  1.00 147.81 ? 521 GLN A CD  1 
ATOM 4054 O OE1 . GLN A 1 521 ? 105.044 85.004  63.897  1.00 147.81 ? 521 GLN A OE1 1 
ATOM 4055 N NE2 . GLN A 1 521 ? 104.269 86.356  62.282  1.00 147.81 ? 521 GLN A NE2 1 
ATOM 4056 N N   . ASN A 1 522 ? 102.037 88.056  67.335  1.00 135.41 ? 522 ASN A N   1 
ATOM 4057 C CA  . ASN A 1 522 ? 102.541 88.153  68.707  1.00 135.41 ? 522 ASN A CA  1 
ATOM 4058 C C   . ASN A 1 522 ? 102.529 89.595  69.206  1.00 135.41 ? 522 ASN A C   1 
ATOM 4059 O O   . ASN A 1 522 ? 103.458 90.040  69.884  1.00 135.41 ? 522 ASN A O   1 
ATOM 4060 C CB  . ASN A 1 522 ? 103.942 87.550  68.831  1.00 135.41 ? 522 ASN A CB  1 
ATOM 4061 C CG  . ASN A 1 522 ? 103.969 86.071  68.511  1.00 135.41 ? 522 ASN A CG  1 
ATOM 4062 O OD1 . ASN A 1 522 ? 103.443 85.252  69.264  1.00 135.41 ? 522 ASN A OD1 1 
ATOM 4063 N ND2 . ASN A 1 522 ? 104.593 85.719  67.393  1.00 135.41 ? 522 ASN A ND2 1 
ATOM 4064 N N   . ASN A 1 523 ? 101.457 90.317  68.876  1.00 143.58 ? 523 ASN A N   1 
ATOM 4065 C CA  . ASN A 1 523 ? 101.266 91.729  69.228  1.00 143.58 ? 523 ASN A CA  1 
ATOM 4066 C C   . ASN A 1 523 ? 102.567 92.521  69.109  1.00 143.58 ? 523 ASN A C   1 
ATOM 4067 O O   . ASN A 1 523 ? 102.990 93.226  70.027  1.00 143.58 ? 523 ASN A O   1 
ATOM 4068 C CB  . ASN A 1 523 ? 100.646 91.875  70.625  1.00 143.58 ? 523 ASN A CB  1 
ATOM 4069 C CG  . ASN A 1 523 ? 101.412 91.125  71.703  1.00 143.58 ? 523 ASN A CG  1 
ATOM 4070 O OD1 . ASN A 1 523 ? 102.319 91.669  72.332  1.00 143.58 ? 523 ASN A OD1 1 
ATOM 4071 N ND2 . ASN A 1 523 ? 101.039 89.869  71.928  1.00 143.58 ? 523 ASN A ND2 1 
ATOM 4072 N N   . LEU A 1 524 ? 103.209 92.393  67.944  1.00 139.66 ? 524 LEU A N   1 
ATOM 4073 C CA  . LEU A 1 524 ? 104.503 93.036  67.733  1.00 139.66 ? 524 LEU A CA  1 
ATOM 4074 C C   . LEU A 1 524 ? 104.386 94.556  67.771  1.00 139.66 ? 524 LEU A C   1 
ATOM 4075 O O   . LEU A 1 524 ? 105.195 95.227  68.423  1.00 139.66 ? 524 LEU A O   1 
ATOM 4076 C CB  . LEU A 1 524 ? 105.109 92.577  66.406  1.00 139.66 ? 524 LEU A CB  1 
ATOM 4077 C CG  . LEU A 1 524 ? 106.589 92.183  66.397  1.00 139.66 ? 524 LEU A CG  1 
ATOM 4078 C CD1 . LEU A 1 524 ? 107.032 91.811  64.992  1.00 139.66 ? 524 LEU A CD1 1 
ATOM 4079 C CD2 . LEU A 1 524 ? 107.465 93.290  66.954  1.00 139.66 ? 524 LEU A CD2 1 
ATOM 4080 N N   . ARG A 1 525 ? 103.391 95.118  67.076  1.00 143.87 ? 525 ARG A N   1 
ATOM 4081 C CA  . ARG A 1 525 ? 103.250 96.571  67.042  1.00 143.87 ? 525 ARG A CA  1 
ATOM 4082 C C   . ARG A 1 525 ? 102.981 97.140  68.429  1.00 143.87 ? 525 ARG A C   1 
ATOM 4083 O O   . ARG A 1 525 ? 103.641 98.099  68.847  1.00 143.87 ? 525 ARG A O   1 
ATOM 4084 C CB  . ARG A 1 525 ? 102.143 96.978  66.067  1.00 143.87 ? 525 ARG A CB  1 
ATOM 4085 C CG  . ARG A 1 525 ? 102.620 97.124  64.629  1.00 143.87 ? 525 ARG A CG  1 
ATOM 4086 C CD  . ARG A 1 525 ? 101.648 97.934  63.783  1.00 143.87 ? 525 ARG A CD  1 
ATOM 4087 N NE  . ARG A 1 525 ? 100.404 97.218  63.525  1.00 143.87 ? 525 ARG A NE  1 
ATOM 4088 C CZ  . ARG A 1 525 ? 99.270  97.421  64.179  1.00 143.87 ? 525 ARG A CZ  1 
ATOM 4089 N NH1 . ARG A 1 525 ? 99.178  98.328  65.139  1.00 143.87 ? 525 ARG A NH1 1 
ATOM 4090 N NH2 . ARG A 1 525 ? 98.200  96.696  63.864  1.00 143.87 ? 525 ARG A NH2 1 
ATOM 4091 N N   . SER A 1 526 ? 102.025 96.564  69.163  1.00 140.04 ? 526 SER A N   1 
ATOM 4092 C CA  . SER A 1 526 ? 101.747 97.055  70.509  1.00 140.04 ? 526 SER A CA  1 
ATOM 4093 C C   . SER A 1 526 ? 102.942 96.859  71.433  1.00 140.04 ? 526 SER A C   1 
ATOM 4094 O O   . SER A 1 526 ? 103.155 97.664  72.346  1.00 140.04 ? 526 SER A O   1 
ATOM 4095 C CB  . SER A 1 526 ? 100.514 96.361  71.082  1.00 140.04 ? 526 SER A CB  1 
ATOM 4096 O OG  . SER A 1 526 ? 100.730 94.970  71.219  1.00 140.04 ? 526 SER A OG  1 
ATOM 4097 N N   . SER A 1 527 ? 103.728 95.801  71.213  1.00 135.12 ? 527 SER A N   1 
ATOM 4098 C CA  . SER A 1 527 ? 104.940 95.601  72.001  1.00 135.12 ? 527 SER A CA  1 
ATOM 4099 C C   . SER A 1 527 ? 105.972 96.683  71.709  1.00 135.12 ? 527 SER A C   1 
ATOM 4100 O O   . SER A 1 527 ? 106.558 97.260  72.632  1.00 135.12 ? 527 SER A O   1 
ATOM 4101 C CB  . SER A 1 527 ? 105.524 94.216  71.719  1.00 135.12 ? 527 SER A CB  1 
ATOM 4102 O OG  . SER A 1 527 ? 104.535 93.208  71.841  1.00 135.12 ? 527 SER A OG  1 
ATOM 4103 N N   . ALA A 1 528 ? 106.213 96.965  70.425  1.00 132.32 ? 528 ALA A N   1 
ATOM 4104 C CA  . ALA A 1 528 ? 107.189 97.985  70.057  1.00 132.32 ? 528 ALA A CA  1 
ATOM 4105 C C   . ALA A 1 528 ? 106.729 99.376  70.480  1.00 132.32 ? 528 ALA A C   1 
ATOM 4106 O O   . ALA A 1 528 ? 107.521 100.157 71.019  1.00 132.32 ? 528 ALA A O   1 
ATOM 4107 C CB  . ALA A 1 528 ? 107.453 97.939  68.553  1.00 132.32 ? 528 ALA A CB  1 
ATOM 4108 N N   . TYR A 1 529 ? 105.455 99.703  70.240  1.00 129.77 ? 529 TYR A N   1 
ATOM 4109 C CA  . TYR A 1 529 ? 104.947 101.021 70.607  1.00 129.77 ? 529 TYR A CA  1 
ATOM 4110 C C   . TYR A 1 529 ? 105.059 101.263 72.107  1.00 129.77 ? 529 TYR A C   1 
ATOM 4111 O O   . TYR A 1 529 ? 105.495 102.338 72.532  1.00 129.77 ? 529 TYR A O   1 
ATOM 4112 C CB  . TYR A 1 529 ? 103.501 101.184 70.142  1.00 129.77 ? 529 TYR A CB  1 
ATOM 4113 C CG  . TYR A 1 529 ? 103.377 101.633 68.703  1.00 129.77 ? 529 TYR A CG  1 
ATOM 4114 C CD1 . TYR A 1 529 ? 103.790 102.902 68.315  1.00 129.77 ? 529 TYR A CD1 1 
ATOM 4115 C CD2 . TYR A 1 529 ? 102.846 100.792 67.735  1.00 129.77 ? 529 TYR A CD2 1 
ATOM 4116 C CE1 . TYR A 1 529 ? 103.682 103.317 67.001  1.00 129.77 ? 529 TYR A CE1 1 
ATOM 4117 C CE2 . TYR A 1 529 ? 102.733 101.197 66.420  1.00 129.77 ? 529 TYR A CE2 1 
ATOM 4118 C CZ  . TYR A 1 529 ? 103.151 102.461 66.059  1.00 129.77 ? 529 TYR A CZ  1 
ATOM 4119 O OH  . TYR A 1 529 ? 103.038 102.867 64.749  1.00 129.77 ? 529 TYR A OH  1 
ATOM 4120 N N   . GLU A 1 530 ? 104.673 100.280 72.925  1.00 130.48 ? 530 GLU A N   1 
ATOM 4121 C CA  . GLU A 1 530 ? 104.862 100.416 74.366  1.00 130.48 ? 530 GLU A CA  1 
ATOM 4122 C C   . GLU A 1 530 ? 106.339 100.544 74.714  1.00 130.48 ? 530 GLU A C   1 
ATOM 4123 O O   . GLU A 1 530 ? 106.715 101.367 75.558  1.00 130.48 ? 530 GLU A O   1 
ATOM 4124 C CB  . GLU A 1 530 ? 104.239 99.228  75.098  1.00 130.48 ? 530 GLU A CB  1 
ATOM 4125 C CG  . GLU A 1 530 ? 104.623 99.136  76.568  1.00 130.48 ? 530 GLU A CG  1 
ATOM 4126 C CD  . GLU A 1 530 ? 104.206 100.357 77.366  1.00 130.48 ? 530 GLU A CD  1 
ATOM 4127 O OE1 . GLU A 1 530 ? 103.161 100.959 77.042  1.00 130.48 ? 530 GLU A OE1 1 
ATOM 4128 O OE2 . GLU A 1 530 ? 104.928 100.718 78.319  1.00 130.48 ? 530 GLU A OE2 1 
ATOM 4129 N N   . SER A 1 531 ? 107.190 99.744  74.069  1.00 120.49 ? 531 SER A N   1 
ATOM 4130 C CA  . SER A 1 531 ? 108.628 99.922  74.223  1.00 120.49 ? 531 SER A CA  1 
ATOM 4131 C C   . SER A 1 531 ? 109.064 101.304 73.755  1.00 120.49 ? 531 SER A C   1 
ATOM 4132 O O   . SER A 1 531 ? 109.909 101.939 74.395  1.00 120.49 ? 531 SER A O   1 
ATOM 4133 C CB  . SER A 1 531 ? 109.378 98.834  73.455  1.00 120.49 ? 531 SER A CB  1 
ATOM 4134 O OG  . SER A 1 531 ? 109.069 97.546  73.959  1.00 120.49 ? 531 SER A OG  1 
ATOM 4135 N N   . LEU A 1 532 ? 108.497 101.784 72.644  1.00 117.95 ? 532 LEU A N   1 
ATOM 4136 C CA  . LEU A 1 532 ? 108.805 103.131 72.175  1.00 117.95 ? 532 LEU A CA  1 
ATOM 4137 C C   . LEU A 1 532 ? 108.331 104.185 73.169  1.00 117.95 ? 532 LEU A C   1 
ATOM 4138 O O   . LEU A 1 532 ? 109.005 105.202 73.370  1.00 117.95 ? 532 LEU A O   1 
ATOM 4139 C CB  . LEU A 1 532 ? 108.178 103.365 70.801  1.00 117.95 ? 532 LEU A CB  1 
ATOM 4140 C CG  . LEU A 1 532 ? 108.462 104.711 70.134  1.00 117.95 ? 532 LEU A CG  1 
ATOM 4141 C CD1 . LEU A 1 532 ? 109.955 104.935 69.978  1.00 117.95 ? 532 LEU A CD1 1 
ATOM 4142 C CD2 . LEU A 1 532 ? 107.763 104.788 68.786  1.00 117.95 ? 532 LEU A CD2 1 
ATOM 4143 N N   . MET A 1 533 ? 107.171 103.965 73.793  1.00 127.99 ? 533 MET A N   1 
ATOM 4144 C CA  . MET A 1 533 ? 106.674 104.913 74.786  1.00 127.99 ? 533 MET A CA  1 
ATOM 4145 C C   . MET A 1 533 ? 107.634 105.036 75.962  1.00 127.99 ? 533 MET A C   1 
ATOM 4146 O O   . MET A 1 533 ? 107.910 106.146 76.434  1.00 127.99 ? 533 MET A O   1 
ATOM 4147 C CB  . MET A 1 533 ? 105.290 104.489 75.280  1.00 127.99 ? 533 MET A CB  1 
ATOM 4148 C CG  . MET A 1 533 ? 104.186 104.572 74.243  1.00 127.99 ? 533 MET A CG  1 
ATOM 4149 S SD  . MET A 1 533 ? 102.632 103.911 74.874  1.00 127.99 ? 533 MET A SD  1 
ATOM 4150 C CE  . MET A 1 533 ? 101.695 103.736 73.359  1.00 127.99 ? 533 MET A CE  1 
ATOM 4151 N N   . GLU A 1 534 ? 108.151 103.907 76.452  1.00 126.67 ? 534 GLU A N   1 
ATOM 4152 C CA  . GLU A 1 534 ? 109.022 103.942 77.623  1.00 126.67 ? 534 GLU A CA  1 
ATOM 4153 C C   . GLU A 1 534 ? 110.379 104.554 77.298  1.00 126.67 ? 534 GLU A C   1 
ATOM 4154 O O   . GLU A 1 534 ? 110.898 105.366 78.073  1.00 126.67 ? 534 GLU A O   1 
ATOM 4155 C CB  . GLU A 1 534 ? 109.192 102.534 78.195  1.00 126.67 ? 534 GLU A CB  1 
ATOM 4156 C CG  . GLU A 1 534 ? 110.181 102.459 79.348  1.00 126.67 ? 534 GLU A CG  1 
ATOM 4157 C CD  . GLU A 1 534 ? 109.837 103.417 80.472  1.00 126.67 ? 534 GLU A CD  1 
ATOM 4158 O OE1 . GLU A 1 534 ? 108.642 103.528 80.814  1.00 126.67 ? 534 GLU A OE1 1 
ATOM 4159 O OE2 . GLU A 1 534 ? 110.760 104.066 81.009  1.00 126.67 ? 534 GLU A OE2 1 
ATOM 4160 N N   . ILE A 1 535 ? 110.973 104.178 76.163  1.00 131.89 ? 535 ILE A N   1 
ATOM 4161 C CA  . ILE A 1 535 ? 112.298 104.686 75.821  1.00 131.89 ? 535 ILE A CA  1 
ATOM 4162 C C   . ILE A 1 535 ? 112.284 106.189 75.564  1.00 131.89 ? 535 ILE A C   1 
ATOM 4163 O O   . ILE A 1 535 ? 113.249 106.877 75.916  1.00 131.89 ? 535 ILE A O   1 
ATOM 4164 C CB  . ILE A 1 535 ? 112.883 103.922 74.616  1.00 131.89 ? 535 ILE A CB  1 
ATOM 4165 C CG1 . ILE A 1 535 ? 114.353 104.288 74.408  1.00 131.89 ? 535 ILE A CG1 1 
ATOM 4166 C CG2 . ILE A 1 535 ? 112.078 104.176 73.347  1.00 131.89 ? 535 ILE A CG2 1 
ATOM 4167 C CD1 . ILE A 1 535 ? 115.250 103.877 75.553  1.00 131.89 ? 535 ILE A CD1 1 
ATOM 4168 N N   . VAL A 1 536 ? 111.217 106.723 74.966  1.00 133.92 ? 536 VAL A N   1 
ATOM 4169 C CA  . VAL A 1 536 ? 111.095 108.171 74.828  1.00 133.92 ? 536 VAL A CA  1 
ATOM 4170 C C   . VAL A 1 536 ? 110.829 108.815 76.183  1.00 133.92 ? 536 VAL A C   1 
ATOM 4171 O O   . VAL A 1 536 ? 111.372 109.881 76.497  1.00 133.92 ? 536 VAL A O   1 
ATOM 4172 C CB  . VAL A 1 536 ? 110.001 108.522 73.803  1.00 133.92 ? 536 VAL A CB  1 
ATOM 4173 C CG1 . VAL A 1 536 ? 109.805 110.025 73.732  1.00 133.92 ? 536 VAL A CG1 1 
ATOM 4174 C CG2 . VAL A 1 536 ? 110.361 107.967 72.433  1.00 133.92 ? 536 VAL A CG2 1 
ATOM 4175 N N   . LYS A 1 537 ? 109.988 108.181 77.006  1.00 141.04 ? 537 LYS A N   1 
ATOM 4176 C CA  . LYS A 1 537 ? 109.693 108.722 78.329  1.00 141.04 ? 537 LYS A CA  1 
ATOM 4177 C C   . LYS A 1 537 ? 110.947 108.794 79.192  1.00 141.04 ? 537 LYS A C   1 
ATOM 4178 O O   . LYS A 1 537 ? 111.115 109.734 79.979  1.00 141.04 ? 537 LYS A O   1 
ATOM 4179 C CB  . LYS A 1 537 ? 108.616 107.877 79.012  1.00 141.04 ? 537 LYS A CB  1 
ATOM 4180 C CG  . LYS A 1 537 ? 108.297 108.294 80.440  1.00 141.04 ? 537 LYS A CG  1 
ATOM 4181 C CD  . LYS A 1 537 ? 107.880 109.755 80.516  1.00 141.04 ? 537 LYS A CD  1 
ATOM 4182 C CE  . LYS A 1 537 ? 106.583 110.004 79.766  1.00 141.04 ? 537 LYS A CE  1 
ATOM 4183 N NZ  . LYS A 1 537 ? 106.218 111.447 79.775  1.00 141.04 ? 537 LYS A NZ  1 
ATOM 4184 N N   . ASN A 1 538 ? 111.846 107.823 79.049  1.00 145.12 ? 538 ASN A N   1 
ATOM 4185 C CA  . ASN A 1 538 ? 113.099 107.817 79.802  1.00 145.12 ? 538 ASN A CA  1 
ATOM 4186 C C   . ASN A 1 538 ? 114.231 108.151 78.842  1.00 145.12 ? 538 ASN A C   1 
ATOM 4187 O O   . ASN A 1 538 ? 114.761 107.287 78.143  1.00 145.12 ? 538 ASN A O   1 
ATOM 4188 C CB  . ASN A 1 538 ? 113.327 106.475 80.483  1.00 145.12 ? 538 ASN A CB  1 
ATOM 4189 C CG  . ASN A 1 538 ? 114.726 106.347 81.052  1.00 145.12 ? 538 ASN A CG  1 
ATOM 4190 O OD1 . ASN A 1 538 ? 115.299 107.320 81.543  1.00 145.12 ? 538 ASN A OD1 1 
ATOM 4191 N ND2 . ASN A 1 538 ? 115.289 105.150 80.972  1.00 145.12 ? 538 ASN A ND2 1 
ATOM 4192 N N   . SER A 1 539 ? 114.611 109.424 78.816  1.00 152.89 ? 539 SER A N   1 
ATOM 4193 C CA  . SER A 1 539 ? 115.707 109.893 77.985  1.00 152.89 ? 539 SER A CA  1 
ATOM 4194 C C   . SER A 1 539 ? 116.587 110.832 78.795  1.00 152.89 ? 539 SER A C   1 
ATOM 4195 O O   . SER A 1 539 ? 116.277 111.169 79.941  1.00 152.89 ? 539 SER A O   1 
ATOM 4196 C CB  . SER A 1 539 ? 115.199 110.606 76.724  1.00 152.89 ? 539 SER A CB  1 
ATOM 4197 O OG  . SER A 1 539 ? 114.410 111.736 77.053  1.00 152.89 ? 539 SER A OG  1 
ATOM 4198 N N   . ALA A 1 540 ? 117.688 111.248 78.185  1.00 166.18 ? 540 ALA A N   1 
ATOM 4199 C CA  . ALA A 1 540 ? 118.657 112.136 78.805  1.00 166.18 ? 540 ALA A CA  1 
ATOM 4200 C C   . ALA A 1 540 ? 118.628 113.493 78.109  1.00 166.18 ? 540 ALA A C   1 
ATOM 4201 O O   . ALA A 1 540 ? 118.074 113.649 77.017  1.00 166.18 ? 540 ALA A O   1 
ATOM 4202 C CB  . ALA A 1 540 ? 120.052 111.513 78.764  1.00 166.18 ? 540 ALA A CB  1 
ATOM 4203 N N   . LYS A 1 541 ? 119.223 114.492 78.767  1.00 177.52 ? 541 LYS A N   1 
ATOM 4204 C CA  . LYS A 1 541 ? 119.238 115.841 78.212  1.00 177.52 ? 541 LYS A CA  1 
ATOM 4205 C C   . LYS A 1 541 ? 119.981 115.920 76.886  1.00 177.52 ? 541 LYS A C   1 
ATOM 4206 O O   . LYS A 1 541 ? 119.592 116.713 76.022  1.00 177.52 ? 541 LYS A O   1 
ATOM 4207 C CB  . LYS A 1 541 ? 119.855 116.822 79.209  1.00 177.52 ? 541 LYS A CB  1 
ATOM 4208 C CG  . LYS A 1 541 ? 119.008 117.066 80.448  1.00 177.52 ? 541 LYS A CG  1 
ATOM 4209 C CD  . LYS A 1 541 ? 119.559 118.210 81.282  1.00 177.52 ? 541 LYS A CD  1 
ATOM 4210 C CE  . LYS A 1 541 ? 118.749 118.408 82.554  1.00 177.52 ? 541 LYS A CE  1 
ATOM 4211 N NZ  . LYS A 1 541 ? 118.810 117.215 83.444  1.00 177.52 ? 541 LYS A NZ  1 
ATOM 4212 N N   . ASP A 1 542 ? 121.033 115.124 76.700  1.00 173.17 ? 542 ASP A N   1 
ATOM 4213 C CA  . ASP A 1 542 ? 121.750 115.111 75.431  1.00 173.17 ? 542 ASP A CA  1 
ATOM 4214 C C   . ASP A 1 542 ? 120.960 114.431 74.322  1.00 173.17 ? 542 ASP A C   1 
ATOM 4215 O O   . ASP A 1 542 ? 121.353 114.525 73.154  1.00 173.17 ? 542 ASP A O   1 
ATOM 4216 C CB  . ASP A 1 542 ? 123.109 114.424 75.594  1.00 173.17 ? 542 ASP A CB  1 
ATOM 4217 C CG  . ASP A 1 542 ? 122.986 112.926 75.802  1.00 173.17 ? 542 ASP A CG  1 
ATOM 4218 O OD1 . ASP A 1 542 ? 121.975 112.486 76.388  1.00 173.17 ? 542 ASP A OD1 1 
ATOM 4219 O OD2 . ASP A 1 542 ? 123.900 112.188 75.378  1.00 173.17 ? 542 ASP A OD2 1 
ATOM 4220 N N   . CYS A 1 543 ? 119.862 113.757 74.657  1.00 168.74 ? 543 CYS A N   1 
ATOM 4221 C CA  . CYS A 1 543 ? 119.013 113.085 73.686  1.00 168.74 ? 543 CYS A CA  1 
ATOM 4222 C C   . CYS A 1 543 ? 117.902 113.983 73.162  1.00 168.74 ? 543 CYS A C   1 
ATOM 4223 O O   . CYS A 1 543 ? 117.012 113.499 72.455  1.00 168.74 ? 543 CYS A O   1 
ATOM 4224 C CB  . CYS A 1 543 ? 118.417 111.816 74.298  1.00 168.74 ? 543 CYS A CB  1 
ATOM 4225 S SG  . CYS A 1 543 ? 119.646 110.633 74.891  1.00 168.74 ? 543 CYS A SG  1 
ATOM 4226 N N   . TYR A 1 544 ? 117.920 115.270 73.512  1.00 171.22 ? 544 TYR A N   1 
ATOM 4227 C CA  . TYR A 1 544 ? 116.902 116.188 73.007  1.00 171.22 ? 544 TYR A CA  1 
ATOM 4228 C C   . TYR A 1 544 ? 116.814 116.218 71.485  1.00 171.22 ? 544 TYR A C   1 
ATOM 4229 O O   . TYR A 1 544 ? 115.684 116.181 70.967  1.00 171.22 ? 544 TYR A O   1 
ATOM 4230 C CB  . TYR A 1 544 ? 117.143 117.596 73.568  1.00 171.22 ? 544 TYR A CB  1 
ATOM 4231 C CG  . TYR A 1 544 ? 116.820 117.728 75.038  1.00 171.22 ? 544 TYR A CG  1 
ATOM 4232 C CD1 . TYR A 1 544 ? 116.076 116.755 75.696  1.00 171.22 ? 544 TYR A CD1 1 
ATOM 4233 C CD2 . TYR A 1 544 ? 117.254 118.828 75.769  1.00 171.22 ? 544 TYR A CD2 1 
ATOM 4234 C CE1 . TYR A 1 544 ? 115.777 116.870 77.040  1.00 171.22 ? 544 TYR A CE1 1 
ATOM 4235 C CE2 . TYR A 1 544 ? 116.960 118.952 77.115  1.00 171.22 ? 544 TYR A CE2 1 
ATOM 4236 C CZ  . TYR A 1 544 ? 116.221 117.971 77.745  1.00 171.22 ? 544 TYR A CZ  1 
ATOM 4237 O OH  . TYR A 1 544 ? 115.924 118.089 79.084  1.00 171.22 ? 544 TYR A OH  1 
ATOM 4238 N N   . PRO A 1 545 ? 117.909 116.305 70.719  1.00 161.81 ? 545 PRO A N   1 
ATOM 4239 C CA  . PRO A 1 545 ? 117.767 116.165 69.260  1.00 161.81 ? 545 PRO A CA  1 
ATOM 4240 C C   . PRO A 1 545 ? 117.186 114.827 68.839  1.00 161.81 ? 545 PRO A C   1 
ATOM 4241 O O   . PRO A 1 545 ? 116.425 114.772 67.865  1.00 161.81 ? 545 PRO A O   1 
ATOM 4242 C CB  . PRO A 1 545 ? 119.202 116.347 68.745  1.00 161.81 ? 545 PRO A CB  1 
ATOM 4243 C CG  . PRO A 1 545 ? 120.073 116.052 69.917  1.00 161.81 ? 545 PRO A CG  1 
ATOM 4244 C CD  . PRO A 1 545 ? 119.311 116.557 71.100  1.00 161.81 ? 545 PRO A CD  1 
ATOM 4245 N N   . ALA A 1 546 ? 117.523 113.744 69.543  1.00 154.09 ? 546 ALA A N   1 
ATOM 4246 C CA  . ALA A 1 546 ? 116.966 112.439 69.204  1.00 154.09 ? 546 ALA A CA  1 
ATOM 4247 C C   . ALA A 1 546 ? 115.457 112.407 69.415  1.00 154.09 ? 546 ALA A C   1 
ATOM 4248 O O   . ALA A 1 546 ? 114.714 111.922 68.553  1.00 154.09 ? 546 ALA A O   1 
ATOM 4249 C CB  . ALA A 1 546 ? 117.647 111.347 70.027  1.00 154.09 ? 546 ALA A CB  1 
ATOM 4250 N N   . VAL A 1 547 ? 114.983 112.916 70.556  1.00 147.08 ? 547 VAL A N   1 
ATOM 4251 C CA  . VAL A 1 547 ? 113.546 112.930 70.808  1.00 147.08 ? 547 VAL A CA  1 
ATOM 4252 C C   . VAL A 1 547 ? 112.859 113.990 69.954  1.00 147.08 ? 547 VAL A C   1 
ATOM 4253 O O   . VAL A 1 547 ? 111.652 113.904 69.699  1.00 147.08 ? 547 VAL A O   1 
ATOM 4254 C CB  . VAL A 1 547 ? 113.259 113.129 72.310  1.00 147.08 ? 547 VAL A CB  1 
ATOM 4255 C CG1 . VAL A 1 547 ? 114.019 112.104 73.134  1.00 147.08 ? 547 VAL A CG1 1 
ATOM 4256 C CG2 . VAL A 1 547 ? 113.613 114.536 72.751  1.00 147.08 ? 547 VAL A CG2 1 
ATOM 4257 N N   . GLN A 1 548 ? 113.603 115.005 69.507  1.00 164.74 ? 548 GLN A N   1 
ATOM 4258 C CA  . GLN A 1 548 ? 113.031 116.000 68.604  1.00 164.74 ? 548 GLN A CA  1 
ATOM 4259 C C   . GLN A 1 548 ? 112.732 115.398 67.237  1.00 164.74 ? 548 GLN A C   1 
ATOM 4260 O O   . GLN A 1 548 ? 111.686 115.685 66.642  1.00 164.74 ? 548 GLN A O   1 
ATOM 4261 C CB  . GLN A 1 548 ? 113.978 117.193 68.465  1.00 164.74 ? 548 GLN A CB  1 
ATOM 4262 C CG  . GLN A 1 548 ? 113.464 118.494 69.068  1.00 164.74 ? 548 GLN A CG  1 
ATOM 4263 C CD  . GLN A 1 548 ? 113.851 118.673 70.526  1.00 164.74 ? 548 GLN A CD  1 
ATOM 4264 O OE1 . GLN A 1 548 ? 114.243 119.762 70.944  1.00 164.74 ? 548 GLN A OE1 1 
ATOM 4265 N NE2 . GLN A 1 548 ? 113.737 117.606 71.308  1.00 164.74 ? 548 GLN A NE2 1 
ATOM 4266 N N   . LYS A 1 549 ? 113.645 114.571 66.720  1.00 164.39 ? 549 LYS A N   1 
ATOM 4267 C CA  . LYS A 1 549 ? 113.449 113.975 65.401  1.00 164.39 ? 549 LYS A CA  1 
ATOM 4268 C C   . LYS A 1 549 ? 112.241 113.046 65.381  1.00 164.39 ? 549 LYS A C   1 
ATOM 4269 O O   . LYS A 1 549 ? 111.391 113.146 64.488  1.00 164.39 ? 549 LYS A O   1 
ATOM 4270 C CB  . LYS A 1 549 ? 114.713 113.227 64.975  1.00 164.39 ? 549 LYS A CB  1 
ATOM 4271 C CG  . LYS A 1 549 ? 115.922 114.129 64.777  1.00 164.39 ? 549 LYS A CG  1 
ATOM 4272 C CD  . LYS A 1 549 ? 117.224 113.350 64.876  1.00 164.39 ? 549 LYS A CD  1 
ATOM 4273 C CE  . LYS A 1 549 ? 118.417 114.291 64.927  1.00 164.39 ? 549 LYS A CE  1 
ATOM 4274 N NZ  . LYS A 1 549 ? 119.679 113.581 65.274  1.00 164.39 ? 549 LYS A NZ  1 
ATOM 4275 N N   . THR A 1 550 ? 112.142 112.140 66.358  1.00 158.80 ? 550 THR A N   1 
ATOM 4276 C CA  . THR A 1 550 ? 111.005 111.228 66.407  1.00 158.80 ? 550 THR A CA  1 
ATOM 4277 C C   . THR A 1 550 ? 109.695 111.952 66.700  1.00 158.80 ? 550 THR A C   1 
ATOM 4278 O O   . THR A 1 550 ? 108.635 111.474 66.281  1.00 158.80 ? 550 THR A O   1 
ATOM 4279 C CB  . THR A 1 550 ? 111.244 110.126 67.443  1.00 158.80 ? 550 THR A CB  1 
ATOM 4280 O OG1 . THR A 1 550 ? 110.130 109.224 67.447  1.00 158.80 ? 550 THR A OG1 1 
ATOM 4281 C CG2 . THR A 1 550 ? 111.420 110.715 68.835  1.00 158.80 ? 550 THR A CG2 1 
ATOM 4282 N N   . THR A 1 551 ? 109.742 113.081 67.415  1.00 164.74 ? 551 THR A N   1 
ATOM 4283 C CA  . THR A 1 551 ? 108.540 113.889 67.601  1.00 164.74 ? 551 THR A CA  1 
ATOM 4284 C C   . THR A 1 551 ? 108.001 114.380 66.263  1.00 164.74 ? 551 THR A C   1 
ATOM 4285 O O   . THR A 1 551 ? 106.788 114.356 66.026  1.00 164.74 ? 551 THR A O   1 
ATOM 4286 C CB  . THR A 1 551 ? 108.835 115.071 68.526  1.00 164.74 ? 551 THR A CB  1 
ATOM 4287 O OG1 . THR A 1 551 ? 109.360 114.590 69.770  1.00 164.74 ? 551 THR A OG1 1 
ATOM 4288 C CG2 . THR A 1 551 ? 107.569 115.871 68.796  1.00 164.74 ? 551 THR A CG2 1 
ATOM 4289 N N   . LEU A 1 552 ? 108.889 114.841 65.379  1.00 170.27 ? 552 LEU A N   1 
ATOM 4290 C CA  . LEU A 1 552 ? 108.474 115.164 64.019  1.00 170.27 ? 552 LEU A CA  1 
ATOM 4291 C C   . LEU A 1 552 ? 108.017 113.920 63.268  1.00 170.27 ? 552 LEU A C   1 
ATOM 4292 O O   . LEU A 1 552 ? 107.034 113.975 62.520  1.00 170.27 ? 552 LEU A O   1 
ATOM 4293 C CB  . LEU A 1 552 ? 109.615 115.851 63.271  1.00 170.27 ? 552 LEU A CB  1 
ATOM 4294 C CG  . LEU A 1 552 ? 109.280 116.433 61.897  1.00 170.27 ? 552 LEU A CG  1 
ATOM 4295 C CD1 . LEU A 1 552 ? 108.194 117.489 62.015  1.00 170.27 ? 552 LEU A CD1 1 
ATOM 4296 C CD2 . LEU A 1 552 ? 110.526 117.012 61.247  1.00 170.27 ? 552 LEU A CD2 1 
ATOM 4297 N N   . VAL A 1 553 ? 108.717 112.797 63.451  1.00 162.35 ? 553 VAL A N   1 
ATOM 4298 C CA  . VAL A 1 553 ? 108.354 111.565 62.756  1.00 162.35 ? 553 VAL A CA  1 
ATOM 4299 C C   . VAL A 1 553 ? 106.979 111.080 63.196  1.00 162.35 ? 553 VAL A C   1 
ATOM 4300 O O   . VAL A 1 553 ? 106.138 110.725 62.362  1.00 162.35 ? 553 VAL A O   1 
ATOM 4301 C CB  . VAL A 1 553 ? 109.434 110.490 62.977  1.00 162.35 ? 553 VAL A CB  1 
ATOM 4302 C CG1 . VAL A 1 553 ? 108.936 109.132 62.503  1.00 162.35 ? 553 VAL A CG1 1 
ATOM 4303 C CG2 . VAL A 1 553 ? 110.716 110.870 62.251  1.00 162.35 ? 553 VAL A CG2 1 
ATOM 4304 N N   . ILE A 1 554 ? 106.724 111.056 64.508  1.00 162.70 ? 554 ILE A N   1 
ATOM 4305 C CA  . ILE A 1 554 ? 105.414 110.631 64.986  1.00 162.70 ? 554 ILE A CA  1 
ATOM 4306 C C   . ILE A 1 554 ? 104.326 111.603 64.546  1.00 162.70 ? 554 ILE A C   1 
ATOM 4307 O O   . ILE A 1 554 ? 103.177 111.191 64.347  1.00 162.70 ? 554 ILE A O   1 
ATOM 4308 C CB  . ILE A 1 554 ? 105.419 110.446 66.518  1.00 162.70 ? 554 ILE A CB  1 
ATOM 4309 C CG1 . ILE A 1 554 ? 104.179 109.671 66.967  1.00 162.70 ? 554 ILE A CG1 1 
ATOM 4310 C CG2 . ILE A 1 554 ? 105.486 111.781 67.241  1.00 162.70 ? 554 ILE A CG2 1 
ATOM 4311 C CD1 . ILE A 1 554 ? 104.094 108.278 66.385  1.00 162.70 ? 554 ILE A CD1 1 
ATOM 4312 N N   . MET A 1 555 ? 104.658 112.887 64.385  1.00 173.06 ? 555 MET A N   1 
ATOM 4313 C CA  . MET A 1 555 ? 103.705 113.829 63.809  1.00 173.06 ? 555 MET A CA  1 
ATOM 4314 C C   . MET A 1 555 ? 103.367 113.448 62.373  1.00 173.06 ? 555 MET A C   1 
ATOM 4315 O O   . MET A 1 555 ? 102.201 113.510 61.964  1.00 173.06 ? 555 MET A O   1 
ATOM 4316 C CB  . MET A 1 555 ? 104.266 115.250 63.876  1.00 173.06 ? 555 MET A CB  1 
ATOM 4317 C CG  . MET A 1 555 ? 103.256 116.307 64.302  1.00 173.06 ? 555 MET A CG  1 
ATOM 4318 S SD  . MET A 1 555 ? 101.859 116.456 63.173  1.00 173.06 ? 555 MET A SD  1 
ATOM 4319 C CE  . MET A 1 555 ? 102.702 116.901 61.657  1.00 173.06 ? 555 MET A CE  1 
ATOM 4320 N N   . GLU A 1 556 ? 104.376 113.052 61.593  1.00 174.02 ? 556 GLU A N   1 
ATOM 4321 C CA  . GLU A 1 556 ? 104.117 112.526 60.257  1.00 174.02 ? 556 GLU A CA  1 
ATOM 4322 C C   . GLU A 1 556 ? 103.319 111.230 60.314  1.00 174.02 ? 556 GLU A C   1 
ATOM 4323 O O   . GLU A 1 556 ? 102.509 110.964 59.418  1.00 174.02 ? 556 GLU A O   1 
ATOM 4324 C CB  . GLU A 1 556 ? 105.432 112.311 59.509  1.00 174.02 ? 556 GLU A CB  1 
ATOM 4325 C CG  . GLU A 1 556 ? 105.905 113.509 58.691  1.00 174.02 ? 556 GLU A CG  1 
ATOM 4326 C CD  . GLU A 1 556 ? 106.440 114.647 59.543  1.00 174.02 ? 556 GLU A CD  1 
ATOM 4327 O OE1 . GLU A 1 556 ? 105.655 115.261 60.296  1.00 174.02 ? 556 GLU A OE1 1 
ATOM 4328 O OE2 . GLU A 1 556 ? 107.653 114.929 59.455  1.00 174.02 ? 556 GLU A OE2 1 
ATOM 4329 N N   . ARG A 1 557 ? 103.539 110.410 61.345  1.00 166.20 ? 557 ARG A N   1 
ATOM 4330 C CA  . ARG A 1 557 ? 102.703 109.229 61.537  1.00 166.20 ? 557 ARG A CA  1 
ATOM 4331 C C   . ARG A 1 557 ? 101.255 109.623 61.797  1.00 166.20 ? 557 ARG A C   1 
ATOM 4332 O O   . ARG A 1 557 ? 100.329 108.950 61.330  1.00 166.20 ? 557 ARG A O   1 
ATOM 4333 C CB  . ARG A 1 557 ? 103.246 108.377 62.683  1.00 166.20 ? 557 ARG A CB  1 
ATOM 4334 C CG  . ARG A 1 557 ? 104.614 107.771 62.412  1.00 166.20 ? 557 ARG A CG  1 
ATOM 4335 C CD  . ARG A 1 557 ? 104.622 106.973 61.116  1.00 166.20 ? 557 ARG A CD  1 
ATOM 4336 N NE  . ARG A 1 557 ? 103.652 105.884 61.134  1.00 166.20 ? 557 ARG A NE  1 
ATOM 4337 C CZ  . ARG A 1 557 ? 103.916 104.653 61.549  1.00 166.20 ? 557 ARG A CZ  1 
ATOM 4338 N NH1 . ARG A 1 557 ? 105.115 104.315 61.994  1.00 166.20 ? 557 ARG A NH1 1 
ATOM 4339 N NH2 . ARG A 1 557 ? 102.953 103.737 61.516  1.00 166.20 ? 557 ARG A NH2 1 
ATOM 4340 N N   . LEU A 1 558 ? 101.042 110.707 62.547  1.00 161.58 ? 558 LEU A N   1 
ATOM 4341 C CA  . LEU A 1 558 ? 99.694  111.242 62.708  1.00 161.58 ? 558 LEU A CA  1 
ATOM 4342 C C   . LEU A 1 558 ? 99.114  111.665 61.364  1.00 161.58 ? 558 LEU A C   1 
ATOM 4343 O O   . LEU A 1 558 ? 97.927  111.444 61.094  1.00 161.58 ? 558 LEU A O   1 
ATOM 4344 C CB  . LEU A 1 558 ? 99.707  112.420 63.682  1.00 161.58 ? 558 LEU A CB  1 
ATOM 4345 C CG  . LEU A 1 558 ? 100.028 112.096 65.143  1.00 161.58 ? 558 LEU A CG  1 
ATOM 4346 C CD1 . LEU A 1 558 ? 100.147 113.370 65.963  1.00 161.58 ? 558 LEU A CD1 1 
ATOM 4347 C CD2 . LEU A 1 558 ? 98.963  111.182 65.725  1.00 161.58 ? 558 LEU A CD2 1 
ATOM 4348 N N   . GLN A 1 559 ? 99.938  112.280 60.511  1.00 174.56 ? 559 GLN A N   1 
ATOM 4349 C CA  . GLN A 1 559 ? 99.485  112.663 59.178  1.00 174.56 ? 559 GLN A CA  1 
ATOM 4350 C C   . GLN A 1 559 ? 99.039  111.450 58.372  1.00 174.56 ? 559 GLN A C   1 
ATOM 4351 O O   . GLN A 1 559 ? 98.057  111.529 57.625  1.00 174.56 ? 559 GLN A O   1 
ATOM 4352 C CB  . GLN A 1 559 ? 100.597 113.421 58.449  1.00 174.56 ? 559 GLN A CB  1 
ATOM 4353 C CG  . GLN A 1 559 ? 100.155 114.134 57.178  1.00 174.56 ? 559 GLN A CG  1 
ATOM 4354 C CD  . GLN A 1 559 ? 100.171 113.232 55.959  1.00 174.56 ? 559 GLN A CD  1 
ATOM 4355 O OE1 . GLN A 1 559 ? 100.826 112.190 55.951  1.00 174.56 ? 559 GLN A OE1 1 
ATOM 4356 N NE2 . GLN A 1 559 ? 99.444  113.629 54.921  1.00 174.56 ? 559 GLN A NE2 1 
ATOM 4357 N N   . GLN A 1 560 ? 99.747  110.325 58.505  1.00 177.65 ? 560 GLN A N   1 
ATOM 4358 C CA  . GLN A 1 560 ? 99.308  109.090 57.862  1.00 177.65 ? 560 GLN A CA  1 
ATOM 4359 C C   . GLN A 1 560 ? 97.941  108.660 58.379  1.00 177.65 ? 560 GLN A C   1 
ATOM 4360 O O   . GLN A 1 560 ? 97.100  108.181 57.609  1.00 177.65 ? 560 GLN A O   1 
ATOM 4361 C CB  . GLN A 1 560 ? 100.340 107.985 58.091  1.00 177.65 ? 560 GLN A CB  1 
ATOM 4362 C CG  . GLN A 1 560 ? 99.974  106.634 57.486  1.00 177.65 ? 560 GLN A CG  1 
ATOM 4363 C CD  . GLN A 1 560 ? 100.127 106.600 55.976  1.00 177.65 ? 560 GLN A CD  1 
ATOM 4364 O OE1 . GLN A 1 560 ? 99.398  107.273 55.248  1.00 177.65 ? 560 GLN A OE1 1 
ATOM 4365 N NE2 . GLN A 1 560 ? 101.082 105.810 55.498  1.00 177.65 ? 560 GLN A NE2 1 
ATOM 4366 N N   . VAL A 1 561 ? 97.705  108.821 59.684  1.00 166.46 ? 561 VAL A N   1 
ATOM 4367 C CA  . VAL A 1 561 ? 96.418  108.463 60.270  1.00 166.46 ? 561 VAL A CA  1 
ATOM 4368 C C   . VAL A 1 561 ? 95.304  109.357 59.735  1.00 166.46 ? 561 VAL A C   1 
ATOM 4369 O O   . VAL A 1 561 ? 94.153  108.918 59.616  1.00 166.46 ? 561 VAL A O   1 
ATOM 4370 C CB  . VAL A 1 561 ? 96.510  108.522 61.807  1.00 166.46 ? 561 VAL A CB  1 
ATOM 4371 C CG1 . VAL A 1 561 ? 95.162  108.224 62.447  1.00 166.46 ? 561 VAL A CG1 1 
ATOM 4372 C CG2 . VAL A 1 561 ? 97.560  107.544 62.308  1.00 166.46 ? 561 VAL A CG2 1 
ATOM 4373 N N   . LEU A 1 562 ? 95.620  110.611 59.396  1.00 177.39 ? 562 LEU A N   1 
ATOM 4374 C CA  . LEU A 1 562 ? 94.588  111.540 58.941  1.00 177.39 ? 562 LEU A CA  1 
ATOM 4375 C C   . LEU A 1 562 ? 93.861  111.013 57.709  1.00 177.39 ? 562 LEU A C   1 
ATOM 4376 O O   . LEU A 1 562 ? 92.625  111.029 57.653  1.00 177.39 ? 562 LEU A O   1 
ATOM 4377 C CB  . LEU A 1 562 ? 95.201  112.908 58.636  1.00 177.39 ? 562 LEU A CB  1 
ATOM 4378 C CG  . LEU A 1 562 ? 96.024  113.638 59.701  1.00 177.39 ? 562 LEU A CG  1 
ATOM 4379 C CD1 . LEU A 1 562 ? 96.439  115.010 59.190  1.00 177.39 ? 562 LEU A CD1 1 
ATOM 4380 C CD2 . LEU A 1 562 ? 95.269  113.761 61.012  1.00 177.39 ? 562 LEU A CD2 1 
ATOM 4381 N N   . GLN A 1 563 ? 94.607  110.536 56.715  1.00 187.65 ? 563 GLN A N   1 
ATOM 4382 C CA  . GLN A 1 563 ? 94.066  110.206 55.401  1.00 187.65 ? 563 GLN A CA  1 
ATOM 4383 C C   . GLN A 1 563 ? 93.793  108.712 55.241  1.00 187.65 ? 563 GLN A C   1 
ATOM 4384 O O   . GLN A 1 563 ? 93.822  108.178 54.130  1.00 187.65 ? 563 GLN A O   1 
ATOM 4385 C CB  . GLN A 1 563 ? 95.009  110.695 54.305  1.00 187.65 ? 563 GLN A CB  1 
ATOM 4386 C CG  . GLN A 1 563 ? 95.598  112.075 54.568  1.00 187.65 ? 563 GLN A CG  1 
ATOM 4387 C CD  . GLN A 1 563 ? 94.539  113.157 54.671  1.00 187.65 ? 563 GLN A CD  1 
ATOM 4388 O OE1 . GLN A 1 563 ? 93.473  113.059 54.064  1.00 187.65 ? 563 GLN A OE1 1 
ATOM 4389 N NE2 . GLN A 1 563 ? 94.830  114.197 55.445  1.00 187.65 ? 563 GLN A NE2 1 
ATOM 4390 N N   . MET A 1 564 ? 93.522  108.012 56.348  1.00 184.30 ? 564 MET A N   1 
ATOM 4391 C CA  . MET A 1 564 ? 93.197  106.593 56.254  1.00 184.30 ? 564 MET A CA  1 
ATOM 4392 C C   . MET A 1 564 ? 91.900  106.242 56.979  1.00 184.30 ? 564 MET A C   1 
ATOM 4393 O O   . MET A 1 564 ? 91.621  105.056 57.188  1.00 184.30 ? 564 MET A O   1 
ATOM 4394 C CB  . MET A 1 564 ? 94.344  105.726 56.793  1.00 184.30 ? 564 MET A CB  1 
ATOM 4395 C CG  . MET A 1 564 ? 94.713  105.992 58.240  1.00 184.30 ? 564 MET A CG  1 
ATOM 4396 S SD  . MET A 1 564 ? 96.001  104.882 58.841  1.00 184.30 ? 564 MET A SD  1 
ATOM 4397 C CE  . MET A 1 564 ? 95.160  103.302 58.752  1.00 184.30 ? 564 MET A CE  1 
ATOM 4398 N N   . GLU A 1 565 ? 91.102  107.238 57.367  1.00 188.30 ? 565 GLU A N   1 
ATOM 4399 C CA  . GLU A 1 565 ? 89.813  106.976 57.995  1.00 188.30 ? 565 GLU A CA  1 
ATOM 4400 C C   . GLU A 1 565 ? 88.783  106.411 57.024  1.00 188.30 ? 565 GLU A C   1 
ATOM 4401 O O   . GLU A 1 565 ? 87.748  105.907 57.473  1.00 188.30 ? 565 GLU A O   1 
ATOM 4402 C CB  . GLU A 1 565 ? 89.265  108.255 58.633  1.00 188.30 ? 565 GLU A CB  1 
ATOM 4403 C CG  . GLU A 1 565 ? 89.083  108.174 60.141  1.00 188.30 ? 565 GLU A CG  1 
ATOM 4404 C CD  . GLU A 1 565 ? 90.400  108.162 60.894  1.00 188.30 ? 565 GLU A CD  1 
ATOM 4405 O OE1 . GLU A 1 565 ? 91.415  108.621 60.329  1.00 188.30 ? 565 GLU A OE1 1 
ATOM 4406 O OE2 . GLU A 1 565 ? 90.421  107.692 62.051  1.00 188.30 ? 565 GLU A OE2 1 
ATOM 4407 N N   . SER A 1 566 ? 89.032  106.488 55.719  1.00 196.91 ? 566 SER A N   1 
ATOM 4408 C CA  . SER A 1 566 ? 88.131  105.944 54.712  1.00 196.91 ? 566 SER A CA  1 
ATOM 4409 C C   . SER A 1 566 ? 88.540  104.553 54.244  1.00 196.91 ? 566 SER A C   1 
ATOM 4410 O O   . SER A 1 566 ? 87.964  104.044 53.277  1.00 196.91 ? 566 SER A O   1 
ATOM 4411 C CB  . SER A 1 566 ? 88.048  106.891 53.512  1.00 196.91 ? 566 SER A CB  1 
ATOM 4412 O OG  . SER A 1 566 ? 89.325  107.087 52.930  1.00 196.91 ? 566 SER A OG  1 
ATOM 4413 N N   . HIS A 1 567 ? 89.516  103.929 54.902  1.00 199.02 ? 567 HIS A N   1 
ATOM 4414 C CA  . HIS A 1 567 ? 90.024  102.625 54.504  1.00 199.02 ? 567 HIS A CA  1 
ATOM 4415 C C   . HIS A 1 567 ? 89.388  101.483 55.285  1.00 199.02 ? 567 HIS A C   1 
ATOM 4416 O O   . HIS A 1 567 ? 89.859  100.344 55.193  1.00 199.02 ? 567 HIS A O   1 
ATOM 4417 C CB  . HIS A 1 567 ? 91.546  102.579 54.666  1.00 199.02 ? 567 HIS A CB  1 
ATOM 4418 C CG  . HIS A 1 567 ? 92.273  103.619 53.871  1.00 199.02 ? 567 HIS A CG  1 
ATOM 4419 N ND1 . HIS A 1 567 ? 93.626  103.846 54.005  1.00 199.02 ? 567 HIS A ND1 1 
ATOM 4420 C CD2 . HIS A 1 567 ? 91.836  104.491 52.931  1.00 199.02 ? 567 HIS A CD2 1 
ATOM 4421 C CE1 . HIS A 1 567 ? 93.991  104.814 53.183  1.00 199.02 ? 567 HIS A CE1 1 
ATOM 4422 N NE2 . HIS A 1 567 ? 92.924  105.223 52.520  1.00 199.02 ? 567 HIS A NE2 1 
ATOM 4423 N N   . ILE A 1 568 ? 88.334  101.756 56.048  1.00 208.93 ? 568 ILE A N   1 
ATOM 4424 C CA  . ILE A 1 568 ? 87.681  100.725 56.848  1.00 208.93 ? 568 ILE A CA  1 
ATOM 4425 C C   . ILE A 1 568 ? 86.730  99.941  55.953  1.00 208.93 ? 568 ILE A C   1 
ATOM 4426 O O   . ILE A 1 568 ? 85.783  100.500 55.391  1.00 208.93 ? 568 ILE A O   1 
ATOM 4427 C CB  . ILE A 1 568 ? 86.937  101.334 58.047  1.00 208.93 ? 568 ILE A CB  1 
ATOM 4428 C CG1 . ILE A 1 568 ? 87.922  101.760 59.140  1.00 208.93 ? 568 ILE A CG1 1 
ATOM 4429 C CG2 . ILE A 1 568 ? 85.926  100.343 58.607  1.00 208.93 ? 568 ILE A CG2 1 
ATOM 4430 C CD1 . ILE A 1 568 ? 88.528  103.131 58.937  1.00 208.93 ? 568 ILE A CD1 1 
ATOM 4431 N N   . GLN A 1 569 ? 86.989  98.642  55.812  1.00 215.84 ? 569 GLN A N   1 
ATOM 4432 C CA  . GLN A 1 569 ? 86.127  97.763  55.034  1.00 215.84 ? 569 GLN A CA  1 
ATOM 4433 C C   . GLN A 1 569 ? 85.768  96.532  55.855  1.00 215.84 ? 569 GLN A C   1 
ATOM 4434 O O   . GLN A 1 569 ? 84.755  95.874  55.598  1.00 215.84 ? 569 GLN A O   1 
ATOM 4435 C CB  . GLN A 1 569 ? 86.805  97.358  53.723  1.00 215.84 ? 569 GLN A CB  1 
ATOM 4436 C CG  . GLN A 1 569 ? 87.209  98.529  52.840  1.00 215.84 ? 569 GLN A CG  1 
ATOM 4437 C CD  . GLN A 1 569 ? 86.025  99.367  52.398  1.00 215.84 ? 569 GLN A CD  1 
ATOM 4438 O OE1 . GLN A 1 569 ? 84.912  98.863  52.249  1.00 215.84 ? 569 GLN A OE1 1 
ATOM 4439 N NE2 . GLN A 1 569 ? 86.260  100.657 52.188  1.00 215.84 ? 569 GLN A NE2 1 
ATOM 4440 N N   . SER A 1 570 ? 86.599  96.218  56.846  1.00 217.12 ? 570 SER A N   1 
ATOM 4441 C CA  . SER A 1 570 ? 86.377  95.093  57.740  1.00 217.12 ? 570 SER A CA  1 
ATOM 4442 C C   . SER A 1 570 ? 86.407  95.580  59.182  1.00 217.12 ? 570 SER A C   1 
ATOM 4443 O O   . SER A 1 570 ? 87.068  96.568  59.513  1.00 217.12 ? 570 SER A O   1 
ATOM 4444 C CB  . SER A 1 570 ? 87.426  93.991  57.533  1.00 217.12 ? 570 SER A CB  1 
ATOM 4445 O OG  . SER A 1 570 ? 87.196  92.900  58.407  1.00 217.12 ? 570 SER A OG  1 
ATOM 4446 N N   . THR A 1 571 ? 85.664  94.874  60.039  1.00 209.81 ? 571 THR A N   1 
ATOM 4447 C CA  . THR A 1 571 ? 85.602  95.246  61.449  1.00 209.81 ? 571 THR A CA  1 
ATOM 4448 C C   . THR A 1 571 ? 86.967  95.130  62.116  1.00 209.81 ? 571 THR A C   1 
ATOM 4449 O O   . THR A 1 571 ? 87.359  96.006  62.897  1.00 209.81 ? 571 THR A O   1 
ATOM 4450 C CB  . THR A 1 571 ? 84.576  94.377  62.177  1.00 209.81 ? 571 THR A CB  1 
ATOM 4451 O OG1 . THR A 1 571 ? 83.303  94.494  61.530  1.00 209.81 ? 571 THR A OG1 1 
ATOM 4452 C CG2 . THR A 1 571 ? 84.440  94.815  63.629  1.00 209.81 ? 571 THR A CG2 1 
ATOM 4453 N N   . SER A 1 572 ? 87.705  94.055  61.822  1.00 194.25 ? 572 SER A N   1 
ATOM 4454 C CA  . SER A 1 572 ? 89.030  93.879  62.408  1.00 194.25 ? 572 SER A CA  1 
ATOM 4455 C C   . SER A 1 572 ? 89.977  95.004  62.013  1.00 194.25 ? 572 SER A C   1 
ATOM 4456 O O   . SER A 1 572 ? 90.867  95.365  62.792  1.00 194.25 ? 572 SER A O   1 
ATOM 4457 C CB  . SER A 1 572 ? 89.612  92.527  61.996  1.00 194.25 ? 572 SER A CB  1 
ATOM 4458 O OG  . SER A 1 572 ? 89.771  92.448  60.591  1.00 194.25 ? 572 SER A OG  1 
ATOM 4459 N N   . ASP A 1 573 ? 89.810  95.560  60.810  1.00 202.69 ? 573 ASP A N   1 
ATOM 4460 C CA  . ASP A 1 573 ? 90.617  96.706  60.407  1.00 202.69 ? 573 ASP A CA  1 
ATOM 4461 C C   . ASP A 1 573 ? 90.365  97.900  61.319  1.00 202.69 ? 573 ASP A C   1 
ATOM 4462 O O   . ASP A 1 573 ? 91.306  98.594  61.723  1.00 202.69 ? 573 ASP A O   1 
ATOM 4463 C CB  . ASP A 1 573 ? 90.320  97.068  58.952  1.00 202.69 ? 573 ASP A CB  1 
ATOM 4464 C CG  . ASP A 1 573 ? 90.443  95.878  58.019  1.00 202.69 ? 573 ASP A CG  1 
ATOM 4465 O OD1 . ASP A 1 573 ? 90.701  94.759  58.510  1.00 202.69 ? 573 ASP A OD1 1 
ATOM 4466 O OD2 . ASP A 1 573 ? 90.280  96.061  56.794  1.00 202.69 ? 573 ASP A OD2 1 
ATOM 4467 N N   . ARG A 1 574 ? 89.097  98.154  61.654  1.00 193.04 ? 574 ARG A N   1 
ATOM 4468 C CA  . ARG A 1 574 ? 88.778  99.220  62.598  1.00 193.04 ? 574 ARG A CA  1 
ATOM 4469 C C   . ARG A 1 574 ? 89.333  98.912  63.983  1.00 193.04 ? 574 ARG A C   1 
ATOM 4470 O O   . ARG A 1 574 ? 89.792  99.818  64.688  1.00 193.04 ? 574 ARG A O   1 
ATOM 4471 C CB  . ARG A 1 574 ? 87.265  99.434  62.659  1.00 193.04 ? 574 ARG A CB  1 
ATOM 4472 C CG  . ARG A 1 574 ? 86.838  100.677 63.427  1.00 193.04 ? 574 ARG A CG  1 
ATOM 4473 C CD  . ARG A 1 574 ? 87.284  101.950 62.721  1.00 193.04 ? 574 ARG A CD  1 
ATOM 4474 N NE  . ARG A 1 574 ? 86.758  103.149 63.364  1.00 193.04 ? 574 ARG A NE  1 
ATOM 4475 C CZ  . ARG A 1 574 ? 87.417  103.873 64.258  1.00 193.04 ? 574 ARG A CZ  1 
ATOM 4476 N NH1 . ARG A 1 574 ? 88.643  103.553 64.640  1.00 193.04 ? 574 ARG A NH1 1 
ATOM 4477 N NH2 . ARG A 1 574 ? 86.833  104.947 64.782  1.00 193.04 ? 574 ARG A NH2 1 
ATOM 4478 N N   . ILE A 1 575 ? 89.291  97.640  64.391  1.00 178.28 ? 575 ILE A N   1 
ATOM 4479 C CA  . ILE A 1 575 ? 89.817  97.252  65.698  1.00 178.28 ? 575 ILE A CA  1 
ATOM 4480 C C   . ILE A 1 575 ? 91.303  97.571  65.793  1.00 178.28 ? 575 ILE A C   1 
ATOM 4481 O O   . ILE A 1 575 ? 91.766  98.151  66.782  1.00 178.28 ? 575 ILE A O   1 
ATOM 4482 C CB  . ILE A 1 575 ? 89.538  95.760  65.963  1.00 178.28 ? 575 ILE A CB  1 
ATOM 4483 C CG1 . ILE A 1 575 ? 88.031  95.502  66.008  1.00 178.28 ? 575 ILE A CG1 1 
ATOM 4484 C CG2 . ILE A 1 575 ? 90.195  95.313  67.260  1.00 178.28 ? 575 ILE A CG2 1 
ATOM 4485 C CD1 . ILE A 1 575 ? 87.662  94.054  66.245  1.00 178.28 ? 575 ILE A CD1 1 
ATOM 4486 N N   . GLN A 1 576 ? 92.074  97.198  64.768  1.00 170.75 ? 576 GLN A N   1 
ATOM 4487 C CA  . GLN A 1 576 ? 93.480  97.589  64.732  1.00 170.75 ? 576 GLN A CA  1 
ATOM 4488 C C   . GLN A 1 576 ? 93.623  99.102  64.635  1.00 170.75 ? 576 GLN A C   1 
ATOM 4489 O O   . GLN A 1 576 ? 94.516  99.688  65.258  1.00 170.75 ? 576 GLN A O   1 
ATOM 4490 C CB  . GLN A 1 576 ? 94.194  96.901  63.569  1.00 170.75 ? 576 GLN A CB  1 
ATOM 4491 C CG  . GLN A 1 576 ? 94.401  95.407  63.774  1.00 170.75 ? 576 GLN A CG  1 
ATOM 4492 C CD  . GLN A 1 576 ? 95.278  94.782  62.705  1.00 170.75 ? 576 GLN A CD  1 
ATOM 4493 O OE1 . GLN A 1 576 ? 95.507  93.573  62.703  1.00 170.75 ? 576 GLN A OE1 1 
ATOM 4494 N NE2 . GLN A 1 576 ? 95.776  95.606  61.791  1.00 170.75 ? 576 GLN A NE2 1 
ATOM 4495 N N   . PHE A 1 577 ? 92.756  99.750  63.853  1.00 171.54 ? 577 PHE A N   1 
ATOM 4496 C CA  . PHE A 1 577 ? 92.742  101.208 63.813  1.00 171.54 ? 577 PHE A CA  1 
ATOM 4497 C C   . PHE A 1 577 ? 92.421  101.786 65.185  1.00 171.54 ? 577 PHE A C   1 
ATOM 4498 O O   . PHE A 1 577 ? 93.034  102.772 65.609  1.00 171.54 ? 577 PHE A O   1 
ATOM 4499 C CB  . PHE A 1 577 ? 91.732  101.693 62.773  1.00 171.54 ? 577 PHE A CB  1 
ATOM 4500 C CG  . PHE A 1 577 ? 92.068  103.028 62.171  1.00 171.54 ? 577 PHE A CG  1 
ATOM 4501 C CD1 . PHE A 1 577 ? 93.111  103.792 62.669  1.00 171.54 ? 577 PHE A CD1 1 
ATOM 4502 C CD2 . PHE A 1 577 ? 91.339  103.519 61.102  1.00 171.54 ? 577 PHE A CD2 1 
ATOM 4503 C CE1 . PHE A 1 577 ? 93.418  105.020 62.112  1.00 171.54 ? 577 PHE A CE1 1 
ATOM 4504 C CE2 . PHE A 1 577 ? 91.640  104.746 60.542  1.00 171.54 ? 577 PHE A CE2 1 
ATOM 4505 C CZ  . PHE A 1 577 ? 92.680  105.497 61.049  1.00 171.54 ? 577 PHE A CZ  1 
ATOM 4506 N N   . ASN A 1 578 ? 91.463  101.182 65.893  1.00 176.13 ? 578 ASN A N   1 
ATOM 4507 C CA  . ASN A 1 578 ? 91.180  101.600 67.261  1.00 176.13 ? 578 ASN A CA  1 
ATOM 4508 C C   . ASN A 1 578 ? 92.397  101.412 68.156  1.00 176.13 ? 578 ASN A C   1 
ATOM 4509 O O   . ASN A 1 578 ? 92.712  102.281 68.978  1.00 176.13 ? 578 ASN A O   1 
ATOM 4510 C CB  . ASN A 1 578 ? 89.984  100.823 67.811  1.00 176.13 ? 578 ASN A CB  1 
ATOM 4511 C CG  . ASN A 1 578 ? 88.676  101.235 67.166  1.00 176.13 ? 578 ASN A CG  1 
ATOM 4512 O OD1 . ASN A 1 578 ? 88.498  102.390 66.779  1.00 176.13 ? 578 ASN A OD1 1 
ATOM 4513 N ND2 . ASN A 1 578 ? 87.752  100.290 67.045  1.00 176.13 ? 578 ASN A ND2 1 
ATOM 4514 N N   . ASP A 1 579 ? 93.089  100.280 68.018  1.00 163.60 ? 579 ASP A N   1 
ATOM 4515 C CA  . ASP A 1 579 ? 94.315  100.068 68.779  1.00 163.60 ? 579 ASP A CA  1 
ATOM 4516 C C   . ASP A 1 579 ? 95.412  101.030 68.337  1.00 163.60 ? 579 ASP A C   1 
ATOM 4517 O O   . ASP A 1 579 ? 96.138  101.581 69.173  1.00 163.60 ? 579 ASP A O   1 
ATOM 4518 C CB  . ASP A 1 579 ? 94.777  98.619  68.631  1.00 163.60 ? 579 ASP A CB  1 
ATOM 4519 C CG  . ASP A 1 579 ? 93.736  97.622  69.110  1.00 163.60 ? 579 ASP A CG  1 
ATOM 4520 O OD1 . ASP A 1 579 ? 92.993  97.942  70.062  1.00 163.60 ? 579 ASP A OD1 1 
ATOM 4521 O OD2 . ASP A 1 579 ? 93.658  96.518  68.532  1.00 163.60 ? 579 ASP A OD2 1 
ATOM 4522 N N   . LEU A 1 580 ? 95.549  101.240 67.025  1.00 162.92 ? 580 LEU A N   1 
ATOM 4523 C CA  . LEU A 1 580 ? 96.600  102.121 66.523  1.00 162.92 ? 580 LEU A CA  1 
ATOM 4524 C C   . LEU A 1 580 ? 96.396  103.555 66.994  1.00 162.92 ? 580 LEU A C   1 
ATOM 4525 O O   . LEU A 1 580 ? 97.349  104.219 67.419  1.00 162.92 ? 580 LEU A O   1 
ATOM 4526 C CB  . LEU A 1 580 ? 96.650  102.060 64.996  1.00 162.92 ? 580 LEU A CB  1 
ATOM 4527 C CG  . LEU A 1 580 ? 97.793  102.828 64.331  1.00 162.92 ? 580 LEU A CG  1 
ATOM 4528 C CD1 . LEU A 1 580 ? 99.135  102.221 64.708  1.00 162.92 ? 580 LEU A CD1 1 
ATOM 4529 C CD2 . LEU A 1 580 ? 97.625  102.871 62.819  1.00 162.92 ? 580 LEU A CD2 1 
ATOM 4530 N N   . GLN A 1 581 ? 95.158  104.050 66.927  1.00 157.31 ? 581 GLN A N   1 
ATOM 4531 C CA  . GLN A 1 581 ? 94.882  105.422 67.344  1.00 157.31 ? 581 GLN A CA  1 
ATOM 4532 C C   . GLN A 1 581 ? 95.157  105.616 68.830  1.00 157.31 ? 581 GLN A C   1 
ATOM 4533 O O   . GLN A 1 581 ? 95.668  106.666 69.239  1.00 157.31 ? 581 GLN A O   1 
ATOM 4534 C CB  . GLN A 1 581 ? 93.437  105.790 67.008  1.00 157.31 ? 581 GLN A CB  1 
ATOM 4535 C CG  . GLN A 1 581 ? 93.180  106.007 65.523  1.00 157.31 ? 581 GLN A CG  1 
ATOM 4536 C CD  . GLN A 1 581 ? 91.703  106.102 65.190  1.00 157.31 ? 581 GLN A CD  1 
ATOM 4537 O OE1 . GLN A 1 581 ? 90.992  105.097 65.176  1.00 157.31 ? 581 GLN A OE1 1 
ATOM 4538 N NE2 . GLN A 1 581 ? 91.234  107.315 64.918  1.00 157.31 ? 581 GLN A NE2 1 
ATOM 4539 N N   . SER A 1 582 ? 94.819  104.621 69.652  1.00 149.67 ? 582 SER A N   1 
ATOM 4540 C CA  . SER A 1 582 ? 95.078  104.726 71.084  1.00 149.67 ? 582 SER A CA  1 
ATOM 4541 C C   . SER A 1 582 ? 96.572  104.783 71.374  1.00 149.67 ? 582 SER A C   1 
ATOM 4542 O O   . SER A 1 582 ? 97.013  105.552 72.236  1.00 149.67 ? 582 SER A O   1 
ATOM 4543 C CB  . SER A 1 582 ? 94.432  103.553 71.821  1.00 149.67 ? 582 SER A CB  1 
ATOM 4544 O OG  . SER A 1 582 ? 94.964  102.317 71.379  1.00 149.67 ? 582 SER A OG  1 
ATOM 4545 N N   . LEU A 1 583 ? 97.366  103.978 70.664  1.00 143.17 ? 583 LEU A N   1 
ATOM 4546 C CA  . LEU A 1 583 ? 98.805  103.958 70.907  1.00 143.17 ? 583 LEU A CA  1 
ATOM 4547 C C   . LEU A 1 583 ? 99.447  105.294 70.557  1.00 143.17 ? 583 LEU A C   1 
ATOM 4548 O O   . LEU A 1 583 ? 100.249 105.825 71.334  1.00 143.17 ? 583 LEU A O   1 
ATOM 4549 C CB  . LEU A 1 583 ? 99.459  102.827 70.113  1.00 143.17 ? 583 LEU A CB  1 
ATOM 4550 C CG  . LEU A 1 583 ? 99.075  101.394 70.487  1.00 143.17 ? 583 LEU A CG  1 
ATOM 4551 C CD1 . LEU A 1 583 ? 99.838  100.392 69.631  1.00 143.17 ? 583 LEU A CD1 1 
ATOM 4552 C CD2 . LEU A 1 583 ? 99.316  101.137 71.966  1.00 143.17 ? 583 LEU A CD2 1 
ATOM 4553 N N   . LEU A 1 584 ? 99.113  105.851 69.390  1.00 147.29 ? 584 LEU A N   1 
ATOM 4554 C CA  . LEU A 1 584 ? 99.689  107.132 68.994  1.00 147.29 ? 584 LEU A CA  1 
ATOM 4555 C C   . LEU A 1 584 ? 99.278  108.247 69.947  1.00 147.29 ? 584 LEU A C   1 
ATOM 4556 O O   . LEU A 1 584 ? 100.108 109.083 70.324  1.00 147.29 ? 584 LEU A O   1 
ATOM 4557 C CB  . LEU A 1 584 ? 99.288  107.473 67.559  1.00 147.29 ? 584 LEU A CB  1 
ATOM 4558 C CG  . LEU A 1 584 ? 100.253 106.995 66.469  1.00 147.29 ? 584 LEU A CG  1 
ATOM 4559 C CD1 . LEU A 1 584 ? 100.223 105.481 66.320  1.00 147.29 ? 584 LEU A CD1 1 
ATOM 4560 C CD2 . LEU A 1 584 ? 99.958  107.670 65.139  1.00 147.29 ? 584 LEU A CD2 1 
ATOM 4561 N N   . CYS A 1 585 ? 98.002  108.284 70.340  1.00 142.80 ? 585 CYS A N   1 
ATOM 4562 C CA  . CYS A 1 585 ? 97.563  109.283 71.309  1.00 142.80 ? 585 CYS A CA  1 
ATOM 4563 C C   . CYS A 1 585 ? 98.267  109.098 72.647  1.00 142.80 ? 585 CYS A C   1 
ATOM 4564 O O   . CYS A 1 585 ? 98.673  110.078 73.283  1.00 142.80 ? 585 CYS A O   1 
ATOM 4565 C CB  . CYS A 1 585 ? 96.046  109.219 71.487  1.00 142.80 ? 585 CYS A CB  1 
ATOM 4566 S SG  . CYS A 1 585 ? 95.101  109.804 70.063  1.00 142.80 ? 585 CYS A SG  1 
ATOM 4567 N N   . ALA A 1 586 ? 98.413  107.848 73.094  1.00 130.65 ? 586 ALA A N   1 
ATOM 4568 C CA  . ALA A 1 586 ? 99.182  107.583 74.305  1.00 130.65 ? 586 ALA A CA  1 
ATOM 4569 C C   . ALA A 1 586 ? 100.638 107.996 74.132  1.00 130.65 ? 586 ALA A C   1 
ATOM 4570 O O   . ALA A 1 586 ? 101.239 108.569 75.048  1.00 130.65 ? 586 ALA A O   1 
ATOM 4571 C CB  . ALA A 1 586 ? 99.084  106.105 74.678  1.00 130.65 ? 586 ALA A CB  1 
ATOM 4572 N N   . THR A 1 587 ? 101.222 107.705 72.967  1.00 125.25 ? 587 THR A N   1 
ATOM 4573 C CA  . THR A 1 587 ? 102.589 108.134 72.690  1.00 125.25 ? 587 THR A CA  1 
ATOM 4574 C C   . THR A 1 587 ? 102.703 109.653 72.667  1.00 125.25 ? 587 THR A C   1 
ATOM 4575 O O   . THR A 1 587 ? 103.742 110.201 73.053  1.00 125.25 ? 587 THR A O   1 
ATOM 4576 C CB  . THR A 1 587 ? 103.066 107.538 71.364  1.00 125.25 ? 587 THR A CB  1 
ATOM 4577 O OG1 . THR A 1 587 ? 102.863 106.120 71.380  1.00 125.25 ? 587 THR A OG1 1 
ATOM 4578 C CG2 . THR A 1 587 ? 104.545 107.822 71.147  1.00 125.25 ? 587 THR A CG2 1 
ATOM 4579 N N   . LEU A 1 588 ? 101.651 110.345 72.223  1.00 127.31 ? 588 LEU A N   1 
ATOM 4580 C CA  . LEU A 1 588 ? 101.648 111.803 72.273  1.00 127.31 ? 588 LEU A CA  1 
ATOM 4581 C C   . LEU A 1 588 ? 101.790 112.298 73.707  1.00 127.31 ? 588 LEU A C   1 
ATOM 4582 O O   . LEU A 1 588 ? 102.486 113.287 73.967  1.00 127.31 ? 588 LEU A O   1 
ATOM 4583 C CB  . LEU A 1 588 ? 100.371 112.354 71.635  1.00 127.31 ? 588 LEU A CB  1 
ATOM 4584 C CG  . LEU A 1 588 ? 100.284 112.322 70.107  1.00 127.31 ? 588 LEU A CG  1 
ATOM 4585 C CD1 . LEU A 1 588 ? 98.979  112.938 69.632  1.00 127.31 ? 588 LEU A CD1 1 
ATOM 4586 C CD2 . LEU A 1 588 ? 101.469 113.038 69.483  1.00 127.31 ? 588 LEU A CD2 1 
ATOM 4587 N N   . GLN A 1 589 ? 101.135 111.621 74.654  1.00 134.62 ? 589 GLN A N   1 
ATOM 4588 C CA  . GLN A 1 589 ? 101.244 112.011 76.057  1.00 134.62 ? 589 GLN A CA  1 
ATOM 4589 C C   . GLN A 1 589 ? 102.682 111.931 76.552  1.00 134.62 ? 589 GLN A C   1 
ATOM 4590 O O   . GLN A 1 589 ? 103.129 112.809 77.298  1.00 134.62 ? 589 GLN A O   1 
ATOM 4591 C CB  . GLN A 1 589 ? 100.337 111.131 76.919  1.00 134.62 ? 589 GLN A CB  1 
ATOM 4592 C CG  . GLN A 1 589 ? 98.868  111.177 76.523  1.00 134.62 ? 589 GLN A CG  1 
ATOM 4593 C CD  . GLN A 1 589 ? 98.021  110.161 77.269  1.00 134.62 ? 589 GLN A CD  1 
ATOM 4594 O OE1 . GLN A 1 589 ? 98.222  109.918 78.459  1.00 134.62 ? 589 GLN A OE1 1 
ATOM 4595 N NE2 . GLN A 1 589 ? 97.069  109.557 76.566  1.00 134.62 ? 589 GLN A NE2 1 
ATOM 4596 N N   . ASN A 1 590 ? 103.417 110.892 76.153  1.00 127.32 ? 590 ASN A N   1 
ATOM 4597 C CA  . ASN A 1 590 ? 104.799 110.754 76.597  1.00 127.32 ? 590 ASN A CA  1 
ATOM 4598 C C   . ASN A 1 590 ? 105.691 111.832 75.992  1.00 127.32 ? 590 ASN A C   1 
ATOM 4599 O O   . ASN A 1 590 ? 106.496 112.448 76.702  1.00 127.32 ? 590 ASN A O   1 
ATOM 4600 C CB  . ASN A 1 590 ? 105.326 109.365 76.246  1.00 127.32 ? 590 ASN A CB  1 
ATOM 4601 C CG  . ASN A 1 590 ? 104.476 108.257 76.836  1.00 127.32 ? 590 ASN A CG  1 
ATOM 4602 O OD1 . ASN A 1 590 ? 104.705 107.816 77.962  1.00 127.32 ? 590 ASN A OD1 1 
ATOM 4603 N ND2 . ASN A 1 590 ? 103.489 107.801 76.075  1.00 127.32 ? 590 ASN A ND2 1 
ATOM 4604 N N   . VAL A 1 591 ? 105.572 112.070 74.684  1.00 120.89 ? 591 VAL A N   1 
ATOM 4605 C CA  . VAL A 1 591 ? 106.450 113.043 74.043  1.00 120.89 ? 591 VAL A CA  1 
ATOM 4606 C C   . VAL A 1 591 ? 106.112 114.465 74.479  1.00 120.89 ? 591 VAL A C   1 
ATOM 4607 O O   . VAL A 1 591 ? 107.018 115.262 74.746  1.00 120.89 ? 591 VAL A O   1 
ATOM 4608 C CB  . VAL A 1 591 ? 106.412 112.897 72.509  1.00 120.89 ? 591 VAL A CB  1 
ATOM 4609 C CG1 . VAL A 1 591 ? 106.958 111.543 72.092  1.00 120.89 ? 591 VAL A CG1 1 
ATOM 4610 C CG2 . VAL A 1 591 ? 105.006 113.088 71.971  1.00 120.89 ? 591 VAL A CG2 1 
ATOM 4611 N N   . LEU A 1 592 ? 104.823 114.806 74.578  1.00 126.42 ? 592 LEU A N   1 
ATOM 4612 C CA  . LEU A 1 592 ? 104.429 116.150 74.981  1.00 126.42 ? 592 LEU A CA  1 
ATOM 4613 C C   . LEU A 1 592 ? 104.889 116.493 76.389  1.00 126.42 ? 592 LEU A C   1 
ATOM 4614 O O   . LEU A 1 592 ? 105.076 117.675 76.697  1.00 126.42 ? 592 LEU A O   1 
ATOM 4615 C CB  . LEU A 1 592 ? 102.910 116.312 74.885  1.00 126.42 ? 592 LEU A CB  1 
ATOM 4616 C CG  . LEU A 1 592 ? 102.309 116.479 73.488  1.00 126.42 ? 592 LEU A CG  1 
ATOM 4617 C CD1 . LEU A 1 592 ? 100.792 116.463 73.556  1.00 126.42 ? 592 LEU A CD1 1 
ATOM 4618 C CD2 . LEU A 1 592 ? 102.796 117.768 72.855  1.00 126.42 ? 592 LEU A CD2 1 
ATOM 4619 N N   . ARG A 1 593 ? 105.069 115.492 77.247  1.00 127.84 ? 593 ARG A N   1 
ATOM 4620 C CA  . ARG A 1 593 ? 105.600 115.710 78.584  1.00 127.84 ? 593 ARG A CA  1 
ATOM 4621 C C   . ARG A 1 593 ? 107.123 115.681 78.625  1.00 127.84 ? 593 ARG A C   1 
ATOM 4622 O O   . ARG A 1 593 ? 107.704 115.962 79.679  1.00 127.84 ? 593 ARG A O   1 
ATOM 4623 C CB  . ARG A 1 593 ? 105.028 114.665 79.548  1.00 127.84 ? 593 ARG A CB  1 
ATOM 4624 C CG  . ARG A 1 593 ? 104.988 115.109 81.002  1.00 127.84 ? 593 ARG A CG  1 
ATOM 4625 C CD  . ARG A 1 593 ? 104.367 114.050 81.904  1.00 127.84 ? 593 ARG A CD  1 
ATOM 4626 N NE  . ARG A 1 593 ? 102.977 113.769 81.560  1.00 127.84 ? 593 ARG A NE  1 
ATOM 4627 C CZ  . ARG A 1 593 ? 102.554 112.635 81.019  1.00 127.84 ? 593 ARG A CZ  1 
ATOM 4628 N NH1 . ARG A 1 593 ? 103.388 111.644 80.750  1.00 127.84 ? 593 ARG A NH1 1 
ATOM 4629 N NH2 . ARG A 1 593 ? 101.259 112.488 80.748  1.00 127.84 ? 593 ARG A NH2 1 
ATOM 4630 N N   . LYS A 1 594 ? 107.782 115.362 77.514  1.00 130.36 ? 594 LYS A N   1 
ATOM 4631 C CA  . LYS A 1 594 ? 109.238 115.263 77.444  1.00 130.36 ? 594 LYS A CA  1 
ATOM 4632 C C   . LYS A 1 594 ? 109.768 116.119 76.298  1.00 130.36 ? 594 LYS A C   1 
ATOM 4633 O O   . LYS A 1 594 ? 110.632 115.706 75.521  1.00 130.36 ? 594 LYS A O   1 
ATOM 4634 C CB  . LYS A 1 594 ? 109.666 113.799 77.298  1.00 130.36 ? 594 LYS A CB  1 
ATOM 4635 C CG  . LYS A 1 594 ? 111.143 113.526 77.581  1.00 130.36 ? 594 LYS A CG  1 
ATOM 4636 C CD  . LYS A 1 594 ? 111.559 114.045 78.949  1.00 130.36 ? 594 LYS A CD  1 
ATOM 4637 C CE  . LYS A 1 594 ? 110.855 113.294 80.069  1.00 130.36 ? 594 LYS A CE  1 
ATOM 4638 N NZ  . LYS A 1 594 ? 111.297 113.773 81.403  1.00 130.36 ? 594 LYS A NZ  1 
ATOM 4639 N N   . VAL A 1 595 ? 109.243 117.338 76.174  1.00 138.86 ? 595 VAL A N   1 
ATOM 4640 C CA  . VAL A 1 595 ? 109.682 118.298 75.171  1.00 138.86 ? 595 VAL A CA  1 
ATOM 4641 C C   . VAL A 1 595 ? 109.845 119.660 75.835  1.00 138.86 ? 595 VAL A C   1 
ATOM 4642 O O   . VAL A 1 595 ? 109.580 119.834 77.028  1.00 138.86 ? 595 VAL A O   1 
ATOM 4643 C CB  . VAL A 1 595 ? 108.710 118.392 73.975  1.00 138.86 ? 595 VAL A CB  1 
ATOM 4644 C CG1 . VAL A 1 595 ? 108.839 117.169 73.081  1.00 138.86 ? 595 VAL A CG1 1 
ATOM 4645 C CG2 . VAL A 1 595 ? 107.279 118.562 74.461  1.00 138.86 ? 595 VAL A CG2 1 
ATOM 4646 N N   . GLN A 1 596 ? 110.276 120.635 75.043  1.00 164.13 ? 596 GLN A N   1 
ATOM 4647 C CA  . GLN A 1 596 ? 110.549 121.981 75.516  1.00 164.13 ? 596 GLN A CA  1 
ATOM 4648 C C   . GLN A 1 596 ? 109.329 122.865 75.288  1.00 164.13 ? 596 GLN A C   1 
ATOM 4649 O O   . GLN A 1 596 ? 108.559 122.661 74.345  1.00 164.13 ? 596 GLN A O   1 
ATOM 4650 C CB  . GLN A 1 596 ? 111.774 122.561 74.800  1.00 164.13 ? 596 GLN A CB  1 
ATOM 4651 C CG  . GLN A 1 596 ? 112.092 124.014 75.125  1.00 164.13 ? 596 GLN A CG  1 
ATOM 4652 C CD  . GLN A 1 596 ? 112.406 124.236 76.593  1.00 164.13 ? 596 GLN A CD  1 
ATOM 4653 O OE1 . GLN A 1 596 ? 112.972 123.367 77.258  1.00 164.13 ? 596 GLN A OE1 1 
ATOM 4654 N NE2 . GLN A 1 596 ? 112.038 125.406 77.106  1.00 164.13 ? 596 GLN A NE2 1 
ATOM 4655 N N   . HIS A 1 597 ? 109.156 123.847 76.177  1.00 177.00 ? 597 HIS A N   1 
ATOM 4656 C CA  . HIS A 1 597 ? 108.008 124.742 76.086  1.00 177.00 ? 597 HIS A CA  1 
ATOM 4657 C C   . HIS A 1 597 ? 107.987 125.477 74.752  1.00 177.00 ? 597 HIS A C   1 
ATOM 4658 O O   . HIS A 1 597 ? 106.928 125.615 74.128  1.00 177.00 ? 597 HIS A O   1 
ATOM 4659 C CB  . HIS A 1 597 ? 108.029 125.730 77.251  1.00 177.00 ? 597 HIS A CB  1 
ATOM 4660 C CG  . HIS A 1 597 ? 108.256 125.086 78.583  1.00 177.00 ? 597 HIS A CG  1 
ATOM 4661 N ND1 . HIS A 1 597 ? 109.503 124.694 79.019  1.00 177.00 ? 597 HIS A ND1 1 
ATOM 4662 C CD2 . HIS A 1 597 ? 107.392 124.758 79.573  1.00 177.00 ? 597 HIS A CD2 1 
ATOM 4663 C CE1 . HIS A 1 597 ? 109.399 124.157 80.222  1.00 177.00 ? 597 HIS A CE1 1 
ATOM 4664 N NE2 . HIS A 1 597 ? 108.129 124.183 80.581  1.00 177.00 ? 597 HIS A NE2 1 
ATOM 4665 N N   . GLN A 1 598 ? 109.148 125.956 74.298  1.00 179.34 ? 598 GLN A N   1 
ATOM 4666 C CA  . GLN A 1 598 ? 109.222 126.597 72.988  1.00 179.34 ? 598 GLN A CA  1 
ATOM 4667 C C   . GLN A 1 598 ? 108.868 125.621 71.872  1.00 179.34 ? 598 GLN A C   1 
ATOM 4668 O O   . GLN A 1 598 ? 108.145 125.975 70.933  1.00 179.34 ? 598 GLN A O   1 
ATOM 4669 C CB  . GLN A 1 598 ? 110.617 127.182 72.768  1.00 179.34 ? 598 GLN A CB  1 
ATOM 4670 C CG  . GLN A 1 598 ? 110.916 127.567 71.327  1.00 179.34 ? 598 GLN A CG  1 
ATOM 4671 C CD  . GLN A 1 598 ? 109.979 128.632 70.794  1.00 179.34 ? 598 GLN A CD  1 
ATOM 4672 O OE1 . GLN A 1 598 ? 109.575 128.592 69.632  1.00 179.34 ? 598 GLN A OE1 1 
ATOM 4673 N NE2 . GLN A 1 598 ? 109.633 129.597 71.639  1.00 179.34 ? 598 GLN A NE2 1 
ATOM 4674 N N   . ASP A 1 599 ? 109.367 124.385 71.959  1.00 179.20 ? 599 ASP A N   1 
ATOM 4675 C CA  . ASP A 1 599 ? 109.081 123.396 70.925  1.00 179.20 ? 599 ASP A CA  1 
ATOM 4676 C C   . ASP A 1 599 ? 107.599 123.046 70.878  1.00 179.20 ? 599 ASP A C   1 
ATOM 4677 O O   . ASP A 1 599 ? 107.101 122.596 69.840  1.00 179.20 ? 599 ASP A O   1 
ATOM 4678 C CB  . ASP A 1 599 ? 109.922 122.141 71.159  1.00 179.20 ? 599 ASP A CB  1 
ATOM 4679 C CG  . ASP A 1 599 ? 110.259 121.412 69.872  1.00 179.20 ? 599 ASP A CG  1 
ATOM 4680 O OD1 . ASP A 1 599 ? 109.405 121.364 68.963  1.00 179.20 ? 599 ASP A OD1 1 
ATOM 4681 O OD2 . ASP A 1 599 ? 111.388 120.888 69.767  1.00 179.20 ? 599 ASP A OD2 1 
ATOM 4682 N N   . ALA A 1 600 ? 106.881 123.249 71.983  1.00 178.68 ? 600 ALA A N   1 
ATOM 4683 C CA  . ALA A 1 600 ? 105.457 122.948 72.026  1.00 178.68 ? 600 ALA A CA  1 
ATOM 4684 C C   . ALA A 1 600 ? 104.616 123.938 71.231  1.00 178.68 ? 600 ALA A C   1 
ATOM 4685 O O   . ALA A 1 600 ? 103.493 123.598 70.841  1.00 178.68 ? 600 ALA A O   1 
ATOM 4686 C CB  . ALA A 1 600 ? 104.971 122.913 73.476  1.00 178.68 ? 600 ALA A CB  1 
ATOM 4687 N N   . LEU A 1 601 ? 105.123 125.149 70.988  1.00 182.12 ? 601 LEU A N   1 
ATOM 4688 C CA  . LEU A 1 601 ? 104.336 126.149 70.272  1.00 182.12 ? 601 LEU A CA  1 
ATOM 4689 C C   . LEU A 1 601 ? 104.076 125.729 68.830  1.00 182.12 ? 601 LEU A C   1 
ATOM 4690 O O   . LEU A 1 601 ? 102.939 125.810 68.348  1.00 182.12 ? 601 LEU A O   1 
ATOM 4691 C CB  . LEU A 1 601 ? 105.039 127.506 70.314  1.00 182.12 ? 601 LEU A CB  1 
ATOM 4692 C CG  . LEU A 1 601 ? 104.655 128.464 71.445  1.00 182.12 ? 601 LEU A CG  1 
ATOM 4693 C CD1 . LEU A 1 601 ? 103.161 128.752 71.416  1.00 182.12 ? 601 LEU A CD1 1 
ATOM 4694 C CD2 . LEU A 1 601 ? 105.072 127.917 72.801  1.00 182.12 ? 601 LEU A CD2 1 
ATOM 4695 N N   . GLN A 1 602 ? 105.118 125.284 68.122  1.00 181.23 ? 602 GLN A N   1 
ATOM 4696 C CA  . GLN A 1 602 ? 104.953 124.912 66.719  1.00 181.23 ? 602 GLN A CA  1 
ATOM 4697 C C   . GLN A 1 602 ? 104.017 123.720 66.566  1.00 181.23 ? 602 GLN A C   1 
ATOM 4698 O O   . GLN A 1 602 ? 103.166 123.703 65.670  1.00 181.23 ? 602 GLN A O   1 
ATOM 4699 C CB  . GLN A 1 602 ? 106.312 124.608 66.087  1.00 181.23 ? 602 GLN A CB  1 
ATOM 4700 C CG  . GLN A 1 602 ? 107.301 125.763 66.129  1.00 181.23 ? 602 GLN A CG  1 
ATOM 4701 C CD  . GLN A 1 602 ? 108.114 125.789 67.408  1.00 181.23 ? 602 GLN A CD  1 
ATOM 4702 O OE1 . GLN A 1 602 ? 107.962 124.924 68.269  1.00 181.23 ? 602 GLN A OE1 1 
ATOM 4703 N NE2 . GLN A 1 602 ? 108.988 126.781 67.535  1.00 181.23 ? 602 GLN A NE2 1 
ATOM 4704 N N   . ILE A 1 603 ? 104.158 122.711 67.431  1.00 172.94 ? 603 ILE A N   1 
ATOM 4705 C CA  . ILE A 1 603 ? 103.328 121.514 67.338  1.00 172.94 ? 603 ILE A CA  1 
ATOM 4706 C C   . ILE A 1 603 ? 101.930 121.711 67.906  1.00 172.94 ? 603 ILE A C   1 
ATOM 4707 O O   . ILE A 1 603 ? 101.082 120.820 67.749  1.00 172.94 ? 603 ILE A O   1 
ATOM 4708 C CB  . ILE A 1 603 ? 104.000 120.322 68.048  1.00 172.94 ? 603 ILE A CB  1 
ATOM 4709 C CG1 . ILE A 1 603 ? 104.187 120.620 69.536  1.00 172.94 ? 603 ILE A CG1 1 
ATOM 4710 C CG2 . ILE A 1 603 ? 105.335 119.999 67.395  1.00 172.94 ? 603 ILE A CG2 1 
ATOM 4711 C CD1 . ILE A 1 603 ? 104.873 119.507 70.296  1.00 172.94 ? 603 ILE A CD1 1 
ATOM 4712 N N   . SER A 1 604 ? 101.661 122.840 68.566  1.00 174.81 ? 604 SER A N   1 
ATOM 4713 C CA  . SER A 1 604 ? 100.360 123.037 69.198  1.00 174.81 ? 604 SER A CA  1 
ATOM 4714 C C   . SER A 1 604 ? 99.234  123.077 68.171  1.00 174.81 ? 604 SER A C   1 
ATOM 4715 O O   . SER A 1 604 ? 98.215  122.395 68.332  1.00 174.81 ? 604 SER A O   1 
ATOM 4716 C CB  . SER A 1 604 ? 100.370 124.320 70.028  1.00 174.81 ? 604 SER A CB  1 
ATOM 4717 O OG  . SER A 1 604 ? 101.335 124.251 71.062  1.00 174.81 ? 604 SER A OG  1 
ATOM 4718 N N   . ASP A 1 605 ? 99.398  123.871 67.111  1.00 178.30 ? 605 ASP A N   1 
ATOM 4719 C CA  . ASP A 1 605 ? 98.317  124.055 66.146  1.00 178.30 ? 605 ASP A CA  1 
ATOM 4720 C C   . ASP A 1 605 ? 98.020  122.766 65.387  1.00 178.30 ? 605 ASP A C   1 
ATOM 4721 O O   . ASP A 1 605 ? 96.854  122.390 65.217  1.00 178.30 ? 605 ASP A O   1 
ATOM 4722 C CB  . ASP A 1 605 ? 98.670  125.183 65.177  1.00 178.30 ? 605 ASP A CB  1 
ATOM 4723 C CG  . ASP A 1 605 ? 97.474  125.659 64.376  1.00 178.30 ? 605 ASP A CG  1 
ATOM 4724 O OD1 . ASP A 1 605 ? 96.346  125.200 64.655  1.00 178.30 ? 605 ASP A OD1 1 
ATOM 4725 O OD2 . ASP A 1 605 ? 97.661  126.494 63.467  1.00 178.30 ? 605 ASP A OD2 1 
ATOM 4726 N N   . VAL A 1 606 ? 99.063  122.076 64.920  1.00 170.57 ? 606 VAL A N   1 
ATOM 4727 C CA  . VAL A 1 606 ? 98.854  120.863 64.135  1.00 170.57 ? 606 VAL A CA  1 
ATOM 4728 C C   . VAL A 1 606 ? 98.235  119.763 64.992  1.00 170.57 ? 606 VAL A C   1 
ATOM 4729 O O   . VAL A 1 606 ? 97.329  119.049 64.546  1.00 170.57 ? 606 VAL A O   1 
ATOM 4730 C CB  . VAL A 1 606 ? 100.174 120.409 63.483  1.00 170.57 ? 606 VAL A CB  1 
ATOM 4731 C CG1 . VAL A 1 606 ? 100.526 121.319 62.316  1.00 170.57 ? 606 VAL A CG1 1 
ATOM 4732 C CG2 . VAL A 1 606 ? 101.301 120.396 64.503  1.00 170.57 ? 606 VAL A CG2 1 
ATOM 4733 N N   . VAL A 1 607 ? 98.715  119.602 66.227  1.00 166.99 ? 607 VAL A N   1 
ATOM 4734 C CA  . VAL A 1 607 ? 98.159  118.584 67.114  1.00 166.99 ? 607 VAL A CA  1 
ATOM 4735 C C   . VAL A 1 607 ? 96.719  118.918 67.486  1.00 166.99 ? 607 VAL A C   1 
ATOM 4736 O O   . VAL A 1 607 ? 95.851  118.037 67.505  1.00 166.99 ? 607 VAL A O   1 
ATOM 4737 C CB  . VAL A 1 607 ? 99.049  118.419 68.360  1.00 166.99 ? 607 VAL A CB  1 
ATOM 4738 C CG1 . VAL A 1 607 ? 98.324  117.633 69.436  1.00 166.99 ? 607 VAL A CG1 1 
ATOM 4739 C CG2 . VAL A 1 607 ? 100.349 117.725 67.986  1.00 166.99 ? 607 VAL A CG2 1 
ATOM 4740 N N   . MET A 1 608 ? 96.440  120.191 67.784  1.00 175.55 ? 608 MET A N   1 
ATOM 4741 C CA  . MET A 1 608 ? 95.080  120.583 68.142  1.00 175.55 ? 608 MET A CA  1 
ATOM 4742 C C   . MET A 1 608 ? 94.108  120.285 67.007  1.00 175.55 ? 608 MET A C   1 
ATOM 4743 O O   . MET A 1 608 ? 93.022  119.741 67.240  1.00 175.55 ? 608 MET A O   1 
ATOM 4744 C CB  . MET A 1 608 ? 95.039  122.067 68.509  1.00 175.55 ? 608 MET A CB  1 
ATOM 4745 C CG  . MET A 1 608 ? 94.073  122.421 69.635  1.00 175.55 ? 608 MET A CG  1 
ATOM 4746 S SD  . MET A 1 608 ? 92.339  122.099 69.254  1.00 175.55 ? 608 MET A SD  1 
ATOM 4747 C CE  . MET A 1 608 ? 92.102  123.145 67.819  1.00 175.55 ? 608 MET A CE  1 
ATOM 4748 N N   . ALA A 1 609 ? 94.483  120.628 65.773  1.00 173.99 ? 609 ALA A N   1 
ATOM 4749 C CA  . ALA A 1 609 ? 93.650  120.279 64.627  1.00 173.99 ? 609 ALA A CA  1 
ATOM 4750 C C   . ALA A 1 609 ? 93.552  118.769 64.458  1.00 173.99 ? 609 ALA A C   1 
ATOM 4751 O O   . ALA A 1 609 ? 92.473  118.239 64.167  1.00 173.99 ? 609 ALA A O   1 
ATOM 4752 C CB  . ALA A 1 609 ? 94.202  120.929 63.359  1.00 173.99 ? 609 ALA A CB  1 
ATOM 4753 N N   . SER A 1 610 ? 94.671  118.060 64.631  1.00 172.41 ? 610 SER A N   1 
ATOM 4754 C CA  . SER A 1 610 ? 94.654  116.604 64.524  1.00 172.41 ? 610 SER A CA  1 
ATOM 4755 C C   . SER A 1 610 ? 93.779  115.979 65.603  1.00 172.41 ? 610 SER A C   1 
ATOM 4756 O O   . SER A 1 610 ? 92.987  115.074 65.319  1.00 172.41 ? 610 SER A O   1 
ATOM 4757 C CB  . SER A 1 610 ? 96.079  116.055 64.604  1.00 172.41 ? 610 SER A CB  1 
ATOM 4758 O OG  . SER A 1 610 ? 96.863  116.512 63.514  1.00 172.41 ? 610 SER A OG  1 
ATOM 4759 N N   . LEU A 1 611 ? 93.913  116.442 66.848  1.00 163.56 ? 611 LEU A N   1 
ATOM 4760 C CA  . LEU A 1 611 ? 93.062  115.932 67.918  1.00 163.56 ? 611 LEU A CA  1 
ATOM 4761 C C   . LEU A 1 611 ? 91.601  116.290 67.680  1.00 163.56 ? 611 LEU A C   1 
ATOM 4762 O O   . LEU A 1 611 ? 90.706  115.482 67.953  1.00 163.56 ? 611 LEU A O   1 
ATOM 4763 C CB  . LEU A 1 611 ? 93.539  116.466 69.269  1.00 163.56 ? 611 LEU A CB  1 
ATOM 4764 C CG  . LEU A 1 611 ? 94.895  115.926 69.733  1.00 163.56 ? 611 LEU A CG  1 
ATOM 4765 C CD1 . LEU A 1 611 ? 95.288  116.516 71.076  1.00 163.56 ? 611 LEU A CD1 1 
ATOM 4766 C CD2 . LEU A 1 611 ? 94.875  114.406 69.797  1.00 163.56 ? 611 LEU A CD2 1 
ATOM 4767 N N   . LEU A 1 612 ? 91.338  117.502 67.183  1.00 179.66 ? 612 LEU A N   1 
ATOM 4768 C CA  . LEU A 1 612 ? 89.965  117.904 66.898  1.00 179.66 ? 612 LEU A CA  1 
ATOM 4769 C C   . LEU A 1 612 ? 89.333  117.008 65.838  1.00 179.66 ? 612 LEU A C   1 
ATOM 4770 O O   . LEU A 1 612 ? 88.213  116.517 66.022  1.00 179.66 ? 612 LEU A O   1 
ATOM 4771 C CB  . LEU A 1 612 ? 89.927  119.369 66.459  1.00 179.66 ? 612 LEU A CB  1 
ATOM 4772 C CG  . LEU A 1 612 ? 88.562  119.979 66.131  1.00 179.66 ? 612 LEU A CG  1 
ATOM 4773 C CD1 . LEU A 1 612 ? 88.462  121.382 66.702  1.00 179.66 ? 612 LEU A CD1 1 
ATOM 4774 C CD2 . LEU A 1 612 ? 88.318  120.002 64.628  1.00 179.66 ? 612 LEU A CD2 1 
ATOM 4775 N N   . ARG A 1 613 ? 90.031  116.788 64.722  1.00 181.81 ? 613 ARG A N   1 
ATOM 4776 C CA  . ARG A 1 613 ? 89.484  115.948 63.663  1.00 181.81 ? 613 ARG A CA  1 
ATOM 4777 C C   . ARG A 1 613 ? 89.392  114.484 64.081  1.00 181.81 ? 613 ARG A C   1 
ATOM 4778 O O   . ARG A 1 613 ? 88.435  113.798 63.702  1.00 181.81 ? 613 ARG A O   1 
ATOM 4779 C CB  . ARG A 1 613 ? 90.313  116.102 62.382  1.00 181.81 ? 613 ARG A CB  1 
ATOM 4780 C CG  . ARG A 1 613 ? 91.682  115.438 62.401  1.00 181.81 ? 613 ARG A CG  1 
ATOM 4781 C CD  . ARG A 1 613 ? 91.643  114.085 61.702  1.00 181.81 ? 613 ARG A CD  1 
ATOM 4782 N NE  . ARG A 1 613 ? 92.428  113.080 62.407  1.00 181.81 ? 613 ARG A NE  1 
ATOM 4783 C CZ  . ARG A 1 613 ? 92.494  111.802 62.060  1.00 181.81 ? 613 ARG A CZ  1 
ATOM 4784 N NH1 . ARG A 1 613 ? 91.822  111.332 61.022  1.00 181.81 ? 613 ARG A NH1 1 
ATOM 4785 N NH2 . ARG A 1 613 ? 93.252  110.974 62.774  1.00 181.81 ? 613 ARG A NH2 1 
ATOM 4786 N N   . MET A 1 614 ? 90.365  113.987 64.849  1.00 178.96 ? 614 MET A N   1 
ATOM 4787 C CA  . MET A 1 614 ? 90.322  112.606 65.313  1.00 178.96 ? 614 MET A CA  1 
ATOM 4788 C C   . MET A 1 614 ? 89.217  112.376 66.334  1.00 178.96 ? 614 MET A C   1 
ATOM 4789 O O   . MET A 1 614 ? 88.703  111.256 66.427  1.00 178.96 ? 614 MET A O   1 
ATOM 4790 C CB  . MET A 1 614 ? 91.683  112.197 65.891  1.00 178.96 ? 614 MET A CB  1 
ATOM 4791 C CG  . MET A 1 614 ? 91.754  112.106 67.409  1.00 178.96 ? 614 MET A CG  1 
ATOM 4792 S SD  . MET A 1 614 ? 91.402  110.451 68.038  1.00 178.96 ? 614 MET A SD  1 
ATOM 4793 C CE  . MET A 1 614 ? 92.697  109.503 67.243  1.00 178.96 ? 614 MET A CE  1 
ATOM 4794 N N   . PHE A 1 615 ? 88.848  113.403 67.104  1.00 170.84 ? 615 PHE A N   1 
ATOM 4795 C CA  . PHE A 1 615 ? 87.691  113.285 67.984  1.00 170.84 ? 615 PHE A CA  1 
ATOM 4796 C C   . PHE A 1 615 ? 86.415  113.079 67.177  1.00 170.84 ? 615 PHE A C   1 
ATOM 4797 O O   . PHE A 1 615 ? 85.582  112.234 67.524  1.00 170.84 ? 615 PHE A O   1 
ATOM 4798 C CB  . PHE A 1 615 ? 87.581  114.529 68.868  1.00 170.84 ? 615 PHE A CB  1 
ATOM 4799 C CG  . PHE A 1 615 ? 86.891  114.292 70.187  1.00 170.84 ? 615 PHE A CG  1 
ATOM 4800 C CD1 . PHE A 1 615 ? 86.177  113.128 70.424  1.00 170.84 ? 615 PHE A CD1 1 
ATOM 4801 C CD2 . PHE A 1 615 ? 86.959  115.242 71.191  1.00 170.84 ? 615 PHE A CD2 1 
ATOM 4802 C CE1 . PHE A 1 615 ? 85.544  112.920 71.637  1.00 170.84 ? 615 PHE A CE1 1 
ATOM 4803 C CE2 . PHE A 1 615 ? 86.331  115.039 72.406  1.00 170.84 ? 615 PHE A CE2 1 
ATOM 4804 C CZ  . PHE A 1 615 ? 85.623  113.876 72.629  1.00 170.84 ? 615 PHE A CZ  1 
ATOM 4805 N N   . GLN A 1 616 ? 86.248  113.838 66.097  1.00 186.62 ? 616 GLN A N   1 
ATOM 4806 C CA  . GLN A 1 616 ? 85.078  113.731 65.235  1.00 186.62 ? 616 GLN A CA  1 
ATOM 4807 C C   . GLN A 1 616 ? 85.216  112.655 64.164  1.00 186.62 ? 616 GLN A C   1 
ATOM 4808 O O   . GLN A 1 616 ? 84.218  112.318 63.519  1.00 186.62 ? 616 GLN A O   1 
ATOM 4809 C CB  . GLN A 1 616 ? 84.783  115.082 64.575  1.00 186.62 ? 616 GLN A CB  1 
ATOM 4810 C CG  . GLN A 1 616 ? 83.858  115.976 65.389  1.00 186.62 ? 616 GLN A CG  1 
ATOM 4811 C CD  . GLN A 1 616 ? 84.300  116.114 66.831  1.00 186.62 ? 616 GLN A CD  1 
ATOM 4812 O OE1 . GLN A 1 616 ? 85.451  116.451 67.111  1.00 186.62 ? 616 GLN A OE1 1 
ATOM 4813 N NE2 . GLN A 1 616 ? 83.387  115.846 67.758  1.00 186.62 ? 616 GLN A NE2 1 
ATOM 4814 N N   . SER A 1 617 ? 86.419  112.115 63.950  1.00 192.98 ? 617 SER A N   1 
ATOM 4815 C CA  . SER A 1 617 ? 86.567  111.015 63.001  1.00 192.98 ? 617 SER A CA  1 
ATOM 4816 C C   . SER A 1 617 ? 85.837  109.769 63.488  1.00 192.98 ? 617 SER A C   1 
ATOM 4817 O O   . SER A 1 617 ? 85.215  109.055 62.693  1.00 192.98 ? 617 SER A O   1 
ATOM 4818 C CB  . SER A 1 617 ? 88.046  110.711 62.764  1.00 192.98 ? 617 SER A CB  1 
ATOM 4819 O OG  . SER A 1 617 ? 88.651  110.177 63.928  1.00 192.98 ? 617 SER A OG  1 
ATOM 4820 N N   . THR A 1 618 ? 85.905  109.492 64.786  1.00 183.74 ? 618 THR A N   1 
ATOM 4821 C CA  . THR A 1 618 ? 85.268  108.325 65.388  1.00 183.74 ? 618 THR A CA  1 
ATOM 4822 C C   . THR A 1 618 ? 83.874  108.726 65.866  1.00 183.74 ? 618 THR A C   1 
ATOM 4823 O O   . THR A 1 618 ? 83.678  109.047 67.042  1.00 183.74 ? 618 THR A O   1 
ATOM 4824 C CB  . THR A 1 618 ? 86.121  107.769 66.527  1.00 183.74 ? 618 THR A CB  1 
ATOM 4825 O OG1 . THR A 1 618 ? 85.314  106.951 67.384  1.00 183.74 ? 618 THR A OG1 1 
ATOM 4826 C CG2 . THR A 1 618 ? 86.752  108.895 67.340  1.00 183.74 ? 618 THR A CG2 1 
ATOM 4827 N N   . ALA A 1 619 ? 82.906  108.710 64.947  1.00 187.92 ? 619 ALA A N   1 
ATOM 4828 C CA  . ALA A 1 619 ? 81.521  108.957 65.334  1.00 187.92 ? 619 ALA A CA  1 
ATOM 4829 C C   . ALA A 1 619 ? 81.031  107.882 66.296  1.00 187.92 ? 619 ALA A C   1 
ATOM 4830 O O   . ALA A 1 619 ? 80.372  108.182 67.298  1.00 187.92 ? 619 ALA A O   1 
ATOM 4831 C CB  . ALA A 1 619 ? 80.630  109.026 64.093  1.00 187.92 ? 619 ALA A CB  1 
ATOM 4832 N N   . GLY A 1 620 ? 81.344  106.618 66.003  1.00 195.52 ? 620 GLY A N   1 
ATOM 4833 C CA  . GLY A 1 620 ? 81.132  105.539 66.941  1.00 195.52 ? 620 GLY A CA  1 
ATOM 4834 C C   . GLY A 1 620 ? 82.414  105.172 67.666  1.00 195.52 ? 620 GLY A C   1 
ATOM 4835 O O   . GLY A 1 620 ? 83.396  105.914 67.671  1.00 195.52 ? 620 GLY A O   1 
ATOM 4836 N N   . SER A 1 621 ? 82.392  103.991 68.287  1.00 190.84 ? 621 SER A N   1 
ATOM 4837 C CA  . SER A 1 621 ? 83.545  103.436 68.999  1.00 190.84 ? 621 SER A CA  1 
ATOM 4838 C C   . SER A 1 621 ? 84.046  104.409 70.073  1.00 190.84 ? 621 SER A C   1 
ATOM 4839 O O   . SER A 1 621 ? 85.096  105.041 69.953  1.00 190.84 ? 621 SER A O   1 
ATOM 4840 C CB  . SER A 1 621 ? 84.663  103.065 68.017  1.00 190.84 ? 621 SER A CB  1 
ATOM 4841 O OG  . SER A 1 621 ? 85.790  102.547 68.700  1.00 190.84 ? 621 SER A OG  1 
ATOM 4842 N N   . GLY A 1 622 ? 83.247  104.513 71.134  1.00 182.13 ? 622 GLY A N   1 
ATOM 4843 C CA  . GLY A 1 622 ? 83.542  105.417 72.230  1.00 182.13 ? 622 GLY A CA  1 
ATOM 4844 C C   . GLY A 1 622 ? 84.817  105.127 72.993  1.00 182.13 ? 622 GLY A C   1 
ATOM 4845 O O   . GLY A 1 622 ? 85.288  106.003 73.723  1.00 182.13 ? 622 GLY A O   1 
ATOM 4846 N N   . GLY A 1 623 ? 85.386  103.928 72.852  1.00 167.79 ? 623 GLY A N   1 
ATOM 4847 C CA  . GLY A 1 623 ? 86.599  103.604 73.585  1.00 167.79 ? 623 GLY A CA  1 
ATOM 4848 C C   . GLY A 1 623 ? 87.788  104.465 73.208  1.00 167.79 ? 623 GLY A C   1 
ATOM 4849 O O   . GLY A 1 623 ? 88.549  104.894 74.080  1.00 167.79 ? 623 GLY A O   1 
ATOM 4850 N N   . VAL A 1 624 ? 87.968  104.733 71.912  1.00 173.80 ? 624 VAL A N   1 
ATOM 4851 C CA  . VAL A 1 624 ? 89.157  105.454 71.467  1.00 173.80 ? 624 VAL A CA  1 
ATOM 4852 C C   . VAL A 1 624 ? 89.135  106.903 71.937  1.00 173.80 ? 624 VAL A C   1 
ATOM 4853 O O   . VAL A 1 624 ? 90.183  107.465 72.280  1.00 173.80 ? 624 VAL A O   1 
ATOM 4854 C CB  . VAL A 1 624 ? 89.310  105.351 69.937  1.00 173.80 ? 624 VAL A CB  1 
ATOM 4855 C CG1 . VAL A 1 624 ? 89.499  103.905 69.531  1.00 173.80 ? 624 VAL A CG1 1 
ATOM 4856 C CG2 . VAL A 1 624 ? 88.107  105.950 69.224  1.00 173.80 ? 624 VAL A CG2 1 
ATOM 4857 N N   . GLN A 1 625 ? 87.959  107.535 71.967  1.00 161.76 ? 625 GLN A N   1 
ATOM 4858 C CA  . GLN A 1 625 ? 87.886  108.927 72.392  1.00 161.76 ? 625 GLN A CA  1 
ATOM 4859 C C   . GLN A 1 625 ? 88.082  109.082 73.895  1.00 161.76 ? 625 GLN A C   1 
ATOM 4860 O O   . GLN A 1 625 ? 88.273  110.207 74.368  1.00 161.76 ? 625 GLN A O   1 
ATOM 4861 C CB  . GLN A 1 625 ? 86.556  109.547 71.961  1.00 161.76 ? 625 GLN A CB  1 
ATOM 4862 C CG  . GLN A 1 625 ? 85.337  109.009 72.686  1.00 161.76 ? 625 GLN A CG  1 
ATOM 4863 C CD  . GLN A 1 625 ? 84.039  109.545 72.115  1.00 161.76 ? 625 GLN A CD  1 
ATOM 4864 O OE1 . GLN A 1 625 ? 84.000  110.042 70.990  1.00 161.76 ? 625 GLN A OE1 1 
ATOM 4865 N NE2 . GLN A 1 625 ? 82.966  109.448 72.892  1.00 161.76 ? 625 GLN A NE2 1 
ATOM 4866 N N   . GLU A 1 626 ? 88.032  107.983 74.653  1.00 165.28 ? 626 GLU A N   1 
ATOM 4867 C CA  . GLU A 1 626 ? 88.410  108.041 76.061  1.00 165.28 ? 626 GLU A CA  1 
ATOM 4868 C C   . GLU A 1 626 ? 89.874  108.431 76.214  1.00 165.28 ? 626 GLU A C   1 
ATOM 4869 O O   . GLU A 1 626 ? 90.230  109.214 77.101  1.00 165.28 ? 626 GLU A O   1 
ATOM 4870 C CB  . GLU A 1 626 ? 88.144  106.693 76.731  1.00 165.28 ? 626 GLU A CB  1 
ATOM 4871 C CG  . GLU A 1 626 ? 86.716  106.197 76.584  1.00 165.28 ? 626 GLU A CG  1 
ATOM 4872 C CD  . GLU A 1 626 ? 86.557  104.753 77.010  1.00 165.28 ? 626 GLU A CD  1 
ATOM 4873 O OE1 . GLU A 1 626 ? 87.585  104.086 77.247  1.00 165.28 ? 626 GLU A OE1 1 
ATOM 4874 O OE2 . GLU A 1 626 ? 85.403  104.283 77.106  1.00 165.28 ? 626 GLU A OE2 1 
ATOM 4875 N N   . ASP A 1 627 ? 90.741  107.882 75.362  1.00 161.07 ? 627 ASP A N   1 
ATOM 4876 C CA  . ASP A 1 627 ? 92.149  108.254 75.382  1.00 161.07 ? 627 ASP A CA  1 
ATOM 4877 C C   . ASP A 1 627 ? 92.391  109.608 74.730  1.00 161.07 ? 627 ASP A C   1 
ATOM 4878 O O   . ASP A 1 627 ? 93.417  110.246 74.997  1.00 161.07 ? 627 ASP A O   1 
ATOM 4879 C CB  . ASP A 1 627 ? 92.983  107.178 74.685  1.00 161.07 ? 627 ASP A CB  1 
ATOM 4880 C CG  . ASP A 1 627 ? 92.747  105.796 75.263  1.00 161.07 ? 627 ASP A CG  1 
ATOM 4881 O OD1 . ASP A 1 627 ? 92.461  105.700 76.474  1.00 161.07 ? 627 ASP A OD1 1 
ATOM 4882 O OD2 . ASP A 1 627 ? 92.846  104.805 74.508  1.00 161.07 ? 627 ASP A OD2 1 
ATOM 4883 N N   . ALA A 1 628 ? 91.475  110.053 73.866  1.00 150.51 ? 628 ALA A N   1 
ATOM 4884 C CA  . ALA A 1 628 ? 91.690  111.297 73.135  1.00 150.51 ? 628 ALA A CA  1 
ATOM 4885 C C   . ALA A 1 628 ? 91.674  112.508 74.059  1.00 150.51 ? 628 ALA A C   1 
ATOM 4886 O O   . ALA A 1 628 ? 92.608  113.317 74.043  1.00 150.51 ? 628 ALA A O   1 
ATOM 4887 C CB  . ALA A 1 628 ? 90.636  111.448 72.038  1.00 150.51 ? 628 ALA A CB  1 
ATOM 4888 N N   . LEU A 1 629 ? 90.632  112.646 74.882  1.00 150.84 ? 629 LEU A N   1 
ATOM 4889 C CA  . LEU A 1 629 ? 90.484  113.870 75.661  1.00 150.84 ? 629 LEU A CA  1 
ATOM 4890 C C   . LEU A 1 629 ? 91.495  113.959 76.798  1.00 150.84 ? 629 LEU A C   1 
ATOM 4891 O O   . LEU A 1 629 ? 91.933  115.063 77.139  1.00 150.84 ? 629 LEU A O   1 
ATOM 4892 C CB  . LEU A 1 629 ? 89.055  113.999 76.200  1.00 150.84 ? 629 LEU A CB  1 
ATOM 4893 C CG  . LEU A 1 629 ? 88.604  113.254 77.458  1.00 150.84 ? 629 LEU A CG  1 
ATOM 4894 C CD1 . LEU A 1 629 ? 87.304  113.850 77.968  1.00 150.84 ? 629 LEU A CD1 1 
ATOM 4895 C CD2 . LEU A 1 629 ? 88.428  111.774 77.188  1.00 150.84 ? 629 LEU A CD2 1 
ATOM 4896 N N   . MET A 1 630 ? 91.869  112.829 77.403  1.00 145.94 ? 630 MET A N   1 
ATOM 4897 C CA  . MET A 1 630 ? 92.949  112.852 78.381  1.00 145.94 ? 630 MET A CA  1 
ATOM 4898 C C   . MET A 1 630 ? 94.286  113.203 77.743  1.00 145.94 ? 630 MET A C   1 
ATOM 4899 O O   . MET A 1 630 ? 95.113  113.855 78.389  1.00 145.94 ? 630 MET A O   1 
ATOM 4900 C CB  . MET A 1 630 ? 93.046  111.511 79.115  1.00 145.94 ? 630 MET A CB  1 
ATOM 4901 C CG  . MET A 1 630 ? 93.241  110.300 78.221  1.00 145.94 ? 630 MET A CG  1 
ATOM 4902 S SD  . MET A 1 630 ? 93.286  108.759 79.158  1.00 145.94 ? 630 MET A SD  1 
ATOM 4903 C CE  . MET A 1 630 ? 91.734  108.861 80.046  1.00 145.94 ? 630 MET A CE  1 
ATOM 4904 N N   . ALA A 1 631 ? 94.513  112.790 76.494  1.00 135.72 ? 631 ALA A N   1 
ATOM 4905 C CA  . ALA A 1 631 ? 95.681  113.263 75.759  1.00 135.72 ? 631 ALA A CA  1 
ATOM 4906 C C   . ALA A 1 631 ? 95.608  114.767 75.529  1.00 135.72 ? 631 ALA A C   1 
ATOM 4907 O O   . ALA A 1 631 ? 96.631  115.460 75.581  1.00 135.72 ? 631 ALA A O   1 
ATOM 4908 C CB  . ALA A 1 631 ? 95.805  112.523 74.428  1.00 135.72 ? 631 ALA A CB  1 
ATOM 4909 N N   . VAL A 1 632 ? 94.407  115.284 75.255  1.00 136.83 ? 632 VAL A N   1 
ATOM 4910 C CA  . VAL A 1 632 ? 94.223  116.727 75.120  1.00 136.83 ? 632 VAL A CA  1 
ATOM 4911 C C   . VAL A 1 632 ? 94.573  117.429 76.425  1.00 136.83 ? 632 VAL A C   1 
ATOM 4912 O O   . VAL A 1 632 ? 95.183  118.506 76.425  1.00 136.83 ? 632 VAL A O   1 
ATOM 4913 C CB  . VAL A 1 632 ? 92.781  117.044 74.676  1.00 136.83 ? 632 VAL A CB  1 
ATOM 4914 C CG1 . VAL A 1 632 ? 92.561  118.548 74.603  1.00 136.83 ? 632 VAL A CG1 1 
ATOM 4915 C CG2 . VAL A 1 632 ? 92.475  116.396 73.335  1.00 136.83 ? 632 VAL A CG2 1 
ATOM 4916 N N   . SER A 1 633 ? 94.195  116.829 77.557  1.00 141.26 ? 633 SER A N   1 
ATOM 4917 C CA  . SER A 1 633 ? 94.509  117.418 78.855  1.00 141.26 ? 633 SER A CA  1 
ATOM 4918 C C   . SER A 1 633 ? 96.013  117.506 79.071  1.00 141.26 ? 633 SER A C   1 
ATOM 4919 O O   . SER A 1 633 ? 96.511  118.498 79.616  1.00 141.26 ? 633 SER A O   1 
ATOM 4920 C CB  . SER A 1 633 ? 93.858  116.605 79.975  1.00 141.26 ? 633 SER A CB  1 
ATOM 4921 O OG  . SER A 1 633 ? 94.410  115.302 80.041  1.00 141.26 ? 633 SER A OG  1 
ATOM 4922 N N   . THR A 1 634 ? 96.752  116.473 78.655  1.00 142.73 ? 634 THR A N   1 
ATOM 4923 C CA  . THR A 1 634 ? 98.205  116.489 78.795  1.00 142.73 ? 634 THR A CA  1 
ATOM 4924 C C   . THR A 1 634 ? 98.817  117.676 78.062  1.00 142.73 ? 634 THR A C   1 
ATOM 4925 O O   . THR A 1 634 ? 99.791  118.270 78.537  1.00 142.73 ? 634 THR A O   1 
ATOM 4926 C CB  . THR A 1 634 ? 98.801  115.179 78.279  1.00 142.73 ? 634 THR A CB  1 
ATOM 4927 O OG1 . THR A 1 634 ? 98.450  114.999 76.900  1.00 142.73 ? 634 THR A OG1 1 
ATOM 4928 C CG2 . THR A 1 634 ? 98.287  113.999 79.094  1.00 142.73 ? 634 THR A CG2 1 
ATOM 4929 N N   . LEU A 1 635 ? 98.264  118.030 76.899  1.00 138.32 ? 635 LEU A N   1 
ATOM 4930 C CA  . LEU A 1 635 ? 98.700  119.240 76.211  1.00 138.32 ? 635 LEU A CA  1 
ATOM 4931 C C   . LEU A 1 635 ? 98.462  120.476 77.071  1.00 138.32 ? 635 LEU A C   1 
ATOM 4932 O O   . LEU A 1 635 ? 99.332  121.349 77.171  1.00 138.32 ? 635 LEU A O   1 
ATOM 4933 C CB  . LEU A 1 635 ? 97.975  119.369 74.871  1.00 138.32 ? 635 LEU A CB  1 
ATOM 4934 C CG  . LEU A 1 635 ? 98.226  120.642 74.060  1.00 138.32 ? 635 LEU A CG  1 
ATOM 4935 C CD1 . LEU A 1 635 ? 99.698  120.778 73.710  1.00 138.32 ? 635 LEU A CD1 1 
ATOM 4936 C CD2 . LEU A 1 635 ? 97.367  120.646 72.804  1.00 138.32 ? 635 LEU A CD2 1 
ATOM 4937 N N   . VAL A 1 636 ? 97.290  120.562 77.705  1.00 149.38 ? 636 VAL A N   1 
ATOM 4938 C CA  . VAL A 1 636 ? 96.975  121.708 78.554  1.00 149.38 ? 636 VAL A CA  1 
ATOM 4939 C C   . VAL A 1 636 ? 97.888  121.740 79.773  1.00 149.38 ? 636 VAL A C   1 
ATOM 4940 O O   . VAL A 1 636 ? 98.279  122.814 80.247  1.00 149.38 ? 636 VAL A O   1 
ATOM 4941 C CB  . VAL A 1 636 ? 95.488  121.674 78.956  1.00 149.38 ? 636 VAL A CB  1 
ATOM 4942 C CG1 . VAL A 1 636 ? 95.118  122.912 79.759  1.00 149.38 ? 636 VAL A CG1 1 
ATOM 4943 C CG2 . VAL A 1 636 ? 94.610  121.549 77.721  1.00 149.38 ? 636 VAL A CG2 1 
ATOM 4944 N N   . GLU A 1 637 ? 98.243  120.564 80.298  1.00 155.54 ? 637 GLU A N   1 
ATOM 4945 C CA  . GLU A 1 637 ? 99.105  120.501 81.476  1.00 155.54 ? 637 GLU A CA  1 
ATOM 4946 C C   . GLU A 1 637 ? 100.480 121.097 81.197  1.00 155.54 ? 637 GLU A C   1 
ATOM 4947 O O   . GLU A 1 637 ? 101.153 121.579 82.116  1.00 155.54 ? 637 GLU A O   1 
ATOM 4948 C CB  . GLU A 1 637 ? 99.241  119.053 81.950  1.00 155.54 ? 637 GLU A CB  1 
ATOM 4949 C CG  . GLU A 1 637 ? 97.955  118.445 82.488  1.00 155.54 ? 637 GLU A CG  1 
ATOM 4950 C CD  . GLU A 1 637 ? 98.066  116.948 82.714  1.00 155.54 ? 637 GLU A CD  1 
ATOM 4951 O OE1 . GLU A 1 637 ? 99.176  116.400 82.552  1.00 155.54 ? 637 GLU A OE1 1 
ATOM 4952 O OE2 . GLU A 1 637 ? 97.041  116.317 83.049  1.00 155.54 ? 637 GLU A OE2 1 
ATOM 4953 N N   . VAL A 1 638 ? 100.916 121.076 79.936  1.00 147.35 ? 638 VAL A N   1 
ATOM 4954 C CA  . VAL A 1 638 ? 102.261 121.547 79.623  1.00 147.35 ? 638 VAL A CA  1 
ATOM 4955 C C   . VAL A 1 638 ? 102.229 122.883 78.883  1.00 147.35 ? 638 VAL A C   1 
ATOM 4956 O O   . VAL A 1 638 ? 103.138 123.706 79.047  1.00 147.35 ? 638 VAL A O   1 
ATOM 4957 C CB  . VAL A 1 638 ? 103.025 120.471 78.829  1.00 147.35 ? 638 VAL A CB  1 
ATOM 4958 C CG1 . VAL A 1 638 ? 102.337 120.182 77.500  1.00 147.35 ? 638 VAL A CG1 1 
ATOM 4959 C CG2 . VAL A 1 638 ? 104.481 120.879 78.625  1.00 147.35 ? 638 VAL A CG2 1 
ATOM 4960 N N   . LEU A 1 639 ? 101.199 123.129 78.068  1.00 158.93 ? 639 LEU A N   1 
ATOM 4961 C CA  . LEU A 1 639 ? 101.130 124.376 77.311  1.00 158.93 ? 639 LEU A CA  1 
ATOM 4962 C C   . LEU A 1 639 ? 101.004 125.585 78.230  1.00 158.93 ? 639 LEU A C   1 
ATOM 4963 O O   . LEU A 1 639 ? 101.649 126.614 77.997  1.00 158.93 ? 639 LEU A O   1 
ATOM 4964 C CB  . LEU A 1 639 ? 99.963  124.334 76.323  1.00 158.93 ? 639 LEU A CB  1 
ATOM 4965 C CG  . LEU A 1 639 ? 100.012 125.344 75.174  1.00 158.93 ? 639 LEU A CG  1 
ATOM 4966 C CD1 . LEU A 1 639 ? 101.250 125.119 74.320  1.00 158.93 ? 639 LEU A CD1 1 
ATOM 4967 C CD2 . LEU A 1 639 ? 98.750  125.265 74.326  1.00 158.93 ? 639 LEU A CD2 1 
ATOM 4968 N N   . GLY A 1 640 ? 100.190 125.483 79.271  1.00 162.88 ? 640 GLY A N   1 
ATOM 4969 C CA  . GLY A 1 640 ? 100.032 126.578 80.215  1.00 162.88 ? 640 GLY A CA  1 
ATOM 4970 C C   . GLY A 1 640 ? 98.751  127.346 79.963  1.00 162.88 ? 640 GLY A C   1 
ATOM 4971 O O   . GLY A 1 640 ? 97.770  126.785 79.474  1.00 162.88 ? 640 GLY A O   1 
ATOM 4972 N N   . GLY A 1 641 ? 98.761  128.633 80.305  1.00 171.70 ? 641 GLY A N   1 
ATOM 4973 C CA  . GLY A 1 641 ? 97.601  129.483 80.129  1.00 171.70 ? 641 GLY A CA  1 
ATOM 4974 C C   . GLY A 1 641 ? 97.480  130.089 78.746  1.00 171.70 ? 641 GLY A C   1 
ATOM 4975 O O   . GLY A 1 641 ? 96.946  131.191 78.593  1.00 171.70 ? 641 GLY A O   1 
ATOM 4976 N N   . GLU A 1 642 ? 97.981  129.386 77.728  1.00 174.95 ? 642 GLU A N   1 
ATOM 4977 C CA  . GLU A 1 642 ? 97.891  129.830 76.342  1.00 174.95 ? 642 GLU A CA  1 
ATOM 4978 C C   . GLU A 1 642 ? 96.928  128.975 75.524  1.00 174.95 ? 642 GLU A C   1 
ATOM 4979 O O   . GLU A 1 642 ? 96.932  129.049 74.291  1.00 174.95 ? 642 GLU A O   1 
ATOM 4980 C CB  . GLU A 1 642 ? 99.276  129.842 75.693  1.00 174.95 ? 642 GLU A CB  1 
ATOM 4981 C CG  . GLU A 1 642 ? 100.184 130.973 76.166  1.00 174.95 ? 642 GLU A CG  1 
ATOM 4982 C CD  . GLU A 1 642 ? 100.729 130.750 77.566  1.00 174.95 ? 642 GLU A CD  1 
ATOM 4983 O OE1 . GLU A 1 642 ? 100.633 129.611 78.071  1.00 174.95 ? 642 GLU A OE1 1 
ATOM 4984 O OE2 . GLU A 1 642 ? 101.256 131.713 78.160  1.00 174.95 ? 642 GLU A OE2 1 
ATOM 4985 N N   . PHE A 1 643 ? 96.108  128.164 76.186  1.00 171.87 ? 643 PHE A N   1 
ATOM 4986 C CA  . PHE A 1 643 ? 95.154  127.290 75.514  1.00 171.87 ? 643 PHE A CA  1 
ATOM 4987 C C   . PHE A 1 643 ? 93.856  127.999 75.147  1.00 171.87 ? 643 PHE A C   1 
ATOM 4988 O O   . PHE A 1 643 ? 92.987  127.385 74.519  1.00 171.87 ? 643 PHE A O   1 
ATOM 4989 C CB  . PHE A 1 643 ? 94.855  126.072 76.397  1.00 171.87 ? 643 PHE A CB  1 
ATOM 4990 C CG  . PHE A 1 643 ? 94.196  124.934 75.667  1.00 171.87 ? 643 PHE A CG  1 
ATOM 4991 C CD1 . PHE A 1 643 ? 94.897  124.195 74.729  1.00 171.87 ? 643 PHE A CD1 1 
ATOM 4992 C CD2 . PHE A 1 643 ? 92.880  124.592 75.932  1.00 171.87 ? 643 PHE A CD2 1 
ATOM 4993 C CE1 . PHE A 1 643 ? 94.293  123.144 74.059  1.00 171.87 ? 643 PHE A CE1 1 
ATOM 4994 C CE2 . PHE A 1 643 ? 92.271  123.543 75.266  1.00 171.87 ? 643 PHE A CE2 1 
ATOM 4995 C CZ  . PHE A 1 643 ? 92.979  122.818 74.329  1.00 171.87 ? 643 PHE A CZ  1 
ATOM 4996 N N   . LEU A 1 644 ? 93.706  129.276 75.512  1.00 170.43 ? 644 LEU A N   1 
ATOM 4997 C CA  . LEU A 1 644 ? 92.495  130.017 75.173  1.00 170.43 ? 644 LEU A CA  1 
ATOM 4998 C C   . LEU A 1 644 ? 92.324  130.203 73.671  1.00 170.43 ? 644 LEU A C   1 
ATOM 4999 O O   . LEU A 1 644 ? 91.225  130.548 73.225  1.00 170.43 ? 644 LEU A O   1 
ATOM 5000 C CB  . LEU A 1 644 ? 92.496  131.383 75.863  1.00 170.43 ? 644 LEU A CB  1 
ATOM 5001 C CG  . LEU A 1 644 ? 92.374  131.421 77.388  1.00 170.43 ? 644 LEU A CG  1 
ATOM 5002 C CD1 . LEU A 1 644 ? 93.738  131.327 78.058  1.00 170.43 ? 644 LEU A CD1 1 
ATOM 5003 C CD2 . LEU A 1 644 ? 91.642  132.676 77.831  1.00 170.43 ? 644 LEU A CD2 1 
ATOM 5004 N N   . LYS A 1 645 ? 93.382  129.992 72.884  1.00 166.27 ? 645 LYS A N   1 
ATOM 5005 C CA  . LYS A 1 645 ? 93.282  130.125 71.435  1.00 166.27 ? 645 LYS A CA  1 
ATOM 5006 C C   . LYS A 1 645 ? 92.343  129.098 70.817  1.00 166.27 ? 645 LYS A C   1 
ATOM 5007 O O   . LYS A 1 645 ? 91.877  129.303 69.691  1.00 166.27 ? 645 LYS A O   1 
ATOM 5008 C CB  . LYS A 1 645 ? 94.668  130.002 70.800  1.00 166.27 ? 645 LYS A CB  1 
ATOM 5009 C CG  . LYS A 1 645 ? 95.700  130.965 71.365  1.00 166.27 ? 645 LYS A CG  1 
ATOM 5010 C CD  . LYS A 1 645 ? 97.077  130.709 70.771  1.00 166.27 ? 645 LYS A CD  1 
ATOM 5011 C CE  . LYS A 1 645 ? 97.536  129.284 71.038  1.00 166.27 ? 645 LYS A CE  1 
ATOM 5012 N NZ  . LYS A 1 645 ? 98.891  129.014 70.484  1.00 166.27 ? 645 LYS A NZ  1 
ATOM 5013 N N   . TYR A 1 646 ? 92.055  128.002 71.521  1.00 173.28 ? 646 TYR A N   1 
ATOM 5014 C CA  . TYR A 1 646 ? 91.206  126.939 70.997  1.00 173.28 ? 646 TYR A CA  1 
ATOM 5015 C C   . TYR A 1 646 ? 89.974  126.692 71.859  1.00 173.28 ? 646 TYR A C   1 
ATOM 5016 O O   . TYR A 1 646 ? 89.188  125.789 71.549  1.00 173.28 ? 646 TYR A O   1 
ATOM 5017 C CB  . TYR A 1 646 ? 92.008  125.640 70.857  1.00 173.28 ? 646 TYR A CB  1 
ATOM 5018 C CG  . TYR A 1 646 ? 93.439  125.845 70.412  1.00 173.28 ? 646 TYR A CG  1 
ATOM 5019 C CD1 . TYR A 1 646 ? 93.748  126.070 69.076  1.00 173.28 ? 646 TYR A CD1 1 
ATOM 5020 C CD2 . TYR A 1 646 ? 94.482  125.808 71.329  1.00 173.28 ? 646 TYR A CD2 1 
ATOM 5021 C CE1 . TYR A 1 646 ? 95.055  126.257 68.667  1.00 173.28 ? 646 TYR A CE1 1 
ATOM 5022 C CE2 . TYR A 1 646 ? 95.791  125.994 70.930  1.00 173.28 ? 646 TYR A CE2 1 
ATOM 5023 C CZ  . TYR A 1 646 ? 96.072  126.218 69.598  1.00 173.28 ? 646 TYR A CZ  1 
ATOM 5024 O OH  . TYR A 1 646 ? 97.375  126.404 69.196  1.00 173.28 ? 646 TYR A OH  1 
ATOM 5025 N N   . MET A 1 647 ? 89.790  127.460 72.936  1.00 179.49 ? 647 MET A N   1 
ATOM 5026 C CA  . MET A 1 647 ? 88.642  127.249 73.813  1.00 179.49 ? 647 MET A CA  1 
ATOM 5027 C C   . MET A 1 647 ? 87.321  127.480 73.091  1.00 179.49 ? 647 MET A C   1 
ATOM 5028 O O   . MET A 1 647 ? 86.380  126.697 73.264  1.00 179.49 ? 647 MET A O   1 
ATOM 5029 C CB  . MET A 1 647 ? 88.743  128.155 75.040  1.00 179.49 ? 647 MET A CB  1 
ATOM 5030 C CG  . MET A 1 647 ? 89.768  127.696 76.064  1.00 179.49 ? 647 MET A CG  1 
ATOM 5031 S SD  . MET A 1 647 ? 89.394  126.064 76.735  1.00 179.49 ? 647 MET A SD  1 
ATOM 5032 C CE  . MET A 1 647 ? 87.829  126.382 77.547  1.00 179.49 ? 647 MET A CE  1 
ATOM 5033 N N   . GLU A 1 648 ? 87.225  128.543 72.287  1.00 183.84 ? 648 GLU A N   1 
ATOM 5034 C CA  . GLU A 1 648 ? 86.003  128.789 71.530  1.00 183.84 ? 648 GLU A CA  1 
ATOM 5035 C C   . GLU A 1 648 ? 85.724  127.684 70.519  1.00 183.84 ? 648 GLU A C   1 
ATOM 5036 O O   . GLU A 1 648 ? 84.559  127.446 70.185  1.00 183.84 ? 648 GLU A O   1 
ATOM 5037 C CB  . GLU A 1 648 ? 86.072  130.147 70.825  1.00 183.84 ? 648 GLU A CB  1 
ATOM 5038 C CG  . GLU A 1 648 ? 86.931  130.181 69.568  1.00 183.84 ? 648 GLU A CG  1 
ATOM 5039 C CD  . GLU A 1 648 ? 88.412  130.037 69.857  1.00 183.84 ? 648 GLU A CD  1 
ATOM 5040 O OE1 . GLU A 1 648 ? 88.825  130.303 71.005  1.00 183.84 ? 648 GLU A OE1 1 
ATOM 5041 O OE2 . GLU A 1 648 ? 89.161  129.655 68.933  1.00 183.84 ? 648 GLU A OE2 1 
ATOM 5042 N N   . ALA A 1 649 ? 86.764  127.013 70.021  1.00 178.40 ? 649 ALA A N   1 
ATOM 5043 C CA  . ALA A 1 649 ? 86.620  125.854 69.149  1.00 178.40 ? 649 ALA A CA  1 
ATOM 5044 C C   . ALA A 1 649 ? 86.735  124.541 69.917  1.00 178.40 ? 649 ALA A C   1 
ATOM 5045 O O   . ALA A 1 649 ? 87.120  123.517 69.343  1.00 178.40 ? 649 ALA A O   1 
ATOM 5046 C CB  . ALA A 1 649 ? 87.649  125.906 68.022  1.00 178.40 ? 649 ALA A CB  1 
ATOM 5047 N N   . PHE A 1 650 ? 86.424  124.557 71.214  1.00 177.98 ? 650 PHE A N   1 
ATOM 5048 C CA  . PHE A 1 650 ? 86.429  123.353 72.037  1.00 177.98 ? 650 PHE A CA  1 
ATOM 5049 C C   . PHE A 1 650 ? 85.168  123.177 72.870  1.00 177.98 ? 650 PHE A C   1 
ATOM 5050 O O   . PHE A 1 650 ? 84.918  122.060 73.340  1.00 177.98 ? 650 PHE A O   1 
ATOM 5051 C CB  . PHE A 1 650 ? 87.645  123.348 72.978  1.00 177.98 ? 650 PHE A CB  1 
ATOM 5052 C CG  . PHE A 1 650 ? 88.064  121.972 73.432  1.00 177.98 ? 650 PHE A CG  1 
ATOM 5053 C CD1 . PHE A 1 650 ? 87.667  120.841 72.735  1.00 177.98 ? 650 PHE A CD1 1 
ATOM 5054 C CD2 . PHE A 1 650 ? 88.853  121.813 74.561  1.00 177.98 ? 650 PHE A CD2 1 
ATOM 5055 C CE1 . PHE A 1 650 ? 88.052  119.580 73.155  1.00 177.98 ? 650 PHE A CE1 1 
ATOM 5056 C CE2 . PHE A 1 650 ? 89.239  120.555 74.985  1.00 177.98 ? 650 PHE A CE2 1 
ATOM 5057 C CZ  . PHE A 1 650 ? 88.839  119.437 74.281  1.00 177.98 ? 650 PHE A CZ  1 
ATOM 5058 N N   . LYS A 1 651 ? 84.381  124.232 73.082  1.00 182.63 ? 651 LYS A N   1 
ATOM 5059 C CA  . LYS A 1 651 ? 83.190  124.118 73.920  1.00 182.63 ? 651 LYS A CA  1 
ATOM 5060 C C   . LYS A 1 651 ? 82.164  123.110 73.411  1.00 182.63 ? 651 LYS A C   1 
ATOM 5061 O O   . LYS A 1 651 ? 81.670  122.317 74.233  1.00 182.63 ? 651 LYS A O   1 
ATOM 5062 C CB  . LYS A 1 651 ? 82.552  125.502 74.093  1.00 182.63 ? 651 LYS A CB  1 
ATOM 5063 C CG  . LYS A 1 651 ? 83.469  126.516 74.751  1.00 182.63 ? 651 LYS A CG  1 
ATOM 5064 C CD  . LYS A 1 651 ? 83.946  126.020 76.108  1.00 182.63 ? 651 LYS A CD  1 
ATOM 5065 C CE  . LYS A 1 651 ? 82.786  125.842 77.077  1.00 182.63 ? 651 LYS A CE  1 
ATOM 5066 N NZ  . LYS A 1 651 ? 82.074  127.124 77.331  1.00 182.63 ? 651 LYS A NZ  1 
ATOM 5067 N N   . PRO A 1 652 ? 81.781  123.083 72.127  1.00 178.14 ? 652 PRO A N   1 
ATOM 5068 C CA  . PRO A 1 652 ? 80.831  122.045 71.688  1.00 178.14 ? 652 PRO A CA  1 
ATOM 5069 C C   . PRO A 1 652 ? 81.342  120.632 71.902  1.00 178.14 ? 652 PRO A C   1 
ATOM 5070 O O   . PRO A 1 652 ? 80.548  119.735 72.210  1.00 178.14 ? 652 PRO A O   1 
ATOM 5071 C CB  . PRO A 1 652 ? 80.630  122.357 70.197  1.00 178.14 ? 652 PRO A CB  1 
ATOM 5072 C CG  . PRO A 1 652 ? 81.810  123.183 69.812  1.00 178.14 ? 652 PRO A CG  1 
ATOM 5073 C CD  . PRO A 1 652 ? 82.128  123.995 71.022  1.00 178.14 ? 652 PRO A CD  1 
ATOM 5074 N N   . PHE A 1 653 ? 82.649  120.406 71.753  1.00 182.42 ? 653 PHE A N   1 
ATOM 5075 C CA  . PHE A 1 653 ? 83.202  119.080 72.004  1.00 182.42 ? 653 PHE A CA  1 
ATOM 5076 C C   . PHE A 1 653 ? 83.268  118.786 73.497  1.00 182.42 ? 653 PHE A C   1 
ATOM 5077 O O   . PHE A 1 653 ? 82.965  117.668 73.930  1.00 182.42 ? 653 PHE A O   1 
ATOM 5078 C CB  . PHE A 1 653 ? 84.583  118.963 71.363  1.00 182.42 ? 653 PHE A CB  1 
ATOM 5079 C CG  . PHE A 1 653 ? 84.644  119.515 69.969  1.00 182.42 ? 653 PHE A CG  1 
ATOM 5080 C CD1 . PHE A 1 653 ? 84.071  118.828 68.913  1.00 182.42 ? 653 PHE A CD1 1 
ATOM 5081 C CD2 . PHE A 1 653 ? 85.265  120.725 69.715  1.00 182.42 ? 653 PHE A CD2 1 
ATOM 5082 C CE1 . PHE A 1 653 ? 84.119  119.336 67.630  1.00 182.42 ? 653 PHE A CE1 1 
ATOM 5083 C CE2 . PHE A 1 653 ? 85.317  121.237 68.432  1.00 182.42 ? 653 PHE A CE2 1 
ATOM 5084 C CZ  . PHE A 1 653 ? 84.744  120.541 67.389  1.00 182.42 ? 653 PHE A CZ  1 
ATOM 5085 N N   . LEU A 1 654 ? 83.666  119.776 74.298  1.00 180.64 ? 654 LEU A N   1 
ATOM 5086 C CA  . LEU A 1 654 ? 83.630  119.613 75.748  1.00 180.64 ? 654 LEU A CA  1 
ATOM 5087 C C   . LEU A 1 654 ? 82.203  119.421 76.243  1.00 180.64 ? 654 LEU A C   1 
ATOM 5088 O O   . LEU A 1 654 ? 81.950  118.582 77.116  1.00 180.64 ? 654 LEU A O   1 
ATOM 5089 C CB  . LEU A 1 654 ? 84.278  120.819 76.428  1.00 180.64 ? 654 LEU A CB  1 
ATOM 5090 C CG  . LEU A 1 654 ? 84.239  120.835 77.958  1.00 180.64 ? 654 LEU A CG  1 
ATOM 5091 C CD1 . LEU A 1 654 ? 84.978  119.636 78.528  1.00 180.64 ? 654 LEU A CD1 1 
ATOM 5092 C CD2 . LEU A 1 654 ? 84.819  122.135 78.494  1.00 180.64 ? 654 LEU A CD2 1 
ATOM 5093 N N   . GLY A 1 655 ? 81.258  120.194 75.703  1.00 183.43 ? 655 GLY A N   1 
ATOM 5094 C CA  . GLY A 1 655 ? 79.874  120.055 76.123  1.00 183.43 ? 655 GLY A CA  1 
ATOM 5095 C C   . GLY A 1 655 ? 79.289  118.697 75.787  1.00 183.43 ? 655 GLY A C   1 
ATOM 5096 O O   . GLY A 1 655 ? 78.639  118.067 76.626  1.00 183.43 ? 655 GLY A O   1 
ATOM 5097 N N   . ILE A 1 656 ? 79.513  118.223 74.558  1.00 181.31 ? 656 ILE A N   1 
ATOM 5098 C CA  . ILE A 1 656 ? 78.967  116.934 74.153  1.00 181.31 ? 656 ILE A CA  1 
ATOM 5099 C C   . ILE A 1 656 ? 79.664  115.781 74.862  1.00 181.31 ? 656 ILE A C   1 
ATOM 5100 O O   . ILE A 1 656 ? 79.104  114.681 74.946  1.00 181.31 ? 656 ILE A O   1 
ATOM 5101 C CB  . ILE A 1 656 ? 79.048  116.775 72.622  1.00 181.31 ? 656 ILE A CB  1 
ATOM 5102 C CG1 . ILE A 1 656 ? 78.061  115.710 72.142  1.00 181.31 ? 656 ILE A CG1 1 
ATOM 5103 C CG2 . ILE A 1 656 ? 80.462  116.422 72.188  1.00 181.31 ? 656 ILE A CG2 1 
ATOM 5104 C CD1 . ILE A 1 656 ? 78.016  115.559 70.642  1.00 181.31 ? 656 ILE A CD1 1 
ATOM 5105 N N   . GLY A 1 657 ? 80.874  116.001 75.381  1.00 178.10 ? 657 GLY A N   1 
ATOM 5106 C CA  . GLY A 1 657 ? 81.544  114.956 76.136  1.00 178.10 ? 657 GLY A CA  1 
ATOM 5107 C C   . GLY A 1 657 ? 80.819  114.619 77.425  1.00 178.10 ? 657 GLY A C   1 
ATOM 5108 O O   . GLY A 1 657 ? 80.703  113.448 77.796  1.00 178.10 ? 657 GLY A O   1 
ATOM 5109 N N   . LEU A 1 658 ? 80.327  115.638 78.125  1.00 176.94 ? 658 LEU A N   1 
ATOM 5110 C CA  . LEU A 1 658 ? 79.527  115.453 79.327  1.00 176.94 ? 658 LEU A CA  1 
ATOM 5111 C C   . LEU A 1 658 ? 78.074  115.111 79.024  1.00 176.94 ? 658 LEU A C   1 
ATOM 5112 O O   . LEU A 1 658 ? 77.335  114.745 79.944  1.00 176.94 ? 658 LEU A O   1 
ATOM 5113 C CB  . LEU A 1 658 ? 79.587  116.713 80.199  1.00 176.94 ? 658 LEU A CB  1 
ATOM 5114 C CG  . LEU A 1 658 ? 80.902  116.988 80.929  1.00 176.94 ? 658 LEU A CG  1 
ATOM 5115 C CD1 . LEU A 1 658 ? 80.893  118.378 81.544  1.00 176.94 ? 658 LEU A CD1 1 
ATOM 5116 C CD2 . LEU A 1 658 ? 81.146  115.934 81.996  1.00 176.94 ? 658 LEU A CD2 1 
ATOM 5117 N N   . LYS A 1 659 ? 77.645  115.223 77.764  1.00 193.83 ? 659 LYS A N   1 
ATOM 5118 C CA  . LYS A 1 659 ? 76.269  114.939 77.372  1.00 193.83 ? 659 LYS A CA  1 
ATOM 5119 C C   . LYS A 1 659 ? 76.069  113.498 76.918  1.00 193.83 ? 659 LYS A C   1 
ATOM 5120 O O   . LYS A 1 659 ? 75.136  113.218 76.154  1.00 193.83 ? 659 LYS A O   1 
ATOM 5121 C CB  . LYS A 1 659 ? 75.824  115.906 76.273  1.00 193.83 ? 659 LYS A CB  1 
ATOM 5122 C CG  . LYS A 1 659 ? 75.553  117.319 76.758  1.00 193.83 ? 659 LYS A CG  1 
ATOM 5123 C CD  . LYS A 1 659 ? 75.193  118.244 75.607  1.00 193.83 ? 659 LYS A CD  1 
ATOM 5124 C CE  . LYS A 1 659 ? 74.940  119.659 76.100  1.00 193.83 ? 659 LYS A CE  1 
ATOM 5125 N NZ  . LYS A 1 659 ? 74.617  120.590 74.985  1.00 193.83 ? 659 LYS A NZ  1 
ATOM 5126 N N   . ASN A 1 660 ? 76.922  112.576 77.362  1.00 191.94 ? 660 ASN A N   1 
ATOM 5127 C CA  . ASN A 1 660 ? 76.800  111.179 76.964  1.00 191.94 ? 660 ASN A CA  1 
ATOM 5128 C C   . ASN A 1 660 ? 75.772  110.432 77.807  1.00 191.94 ? 660 ASN A C   1 
ATOM 5129 O O   . ASN A 1 660 ? 74.820  109.862 77.264  1.00 191.94 ? 660 ASN A O   1 
ATOM 5130 C CB  . ASN A 1 660 ? 78.163  110.488 77.056  1.00 191.94 ? 660 ASN A CB  1 
ATOM 5131 C CG  . ASN A 1 660 ? 78.142  109.083 76.488  1.00 191.94 ? 660 ASN A CG  1 
ATOM 5132 O OD1 . ASN A 1 660 ? 77.266  108.733 75.698  1.00 191.94 ? 660 ASN A OD1 1 
ATOM 5133 N ND2 . ASN A 1 660 ? 79.112  108.271 76.887  1.00 191.94 ? 660 ASN A ND2 1 
ATOM 5134 N N   . TYR A 1 661 ? 75.963  110.414 79.126  1.00 198.49 ? 661 TYR A N   1 
ATOM 5135 C CA  . TYR A 1 661 ? 75.097  109.745 80.096  1.00 198.49 ? 661 TYR A CA  1 
ATOM 5136 C C   . TYR A 1 661 ? 75.051  108.232 79.911  1.00 198.49 ? 661 TYR A C   1 
ATOM 5137 O O   . TYR A 1 661 ? 74.284  107.553 80.605  1.00 198.49 ? 661 TYR A O   1 
ATOM 5138 C CB  . TYR A 1 661 ? 73.666  110.304 80.069  1.00 198.49 ? 661 TYR A CB  1 
ATOM 5139 C CG  . TYR A 1 661 ? 73.570  111.786 79.788  1.00 198.49 ? 661 TYR A CG  1 
ATOM 5140 C CD1 . TYR A 1 661 ? 74.049  112.721 80.696  1.00 198.49 ? 661 TYR A CD1 1 
ATOM 5141 C CD2 . TYR A 1 661 ? 72.982  112.250 78.618  1.00 198.49 ? 661 TYR A CD2 1 
ATOM 5142 C CE1 . TYR A 1 661 ? 73.955  114.076 80.440  1.00 198.49 ? 661 TYR A CE1 1 
ATOM 5143 C CE2 . TYR A 1 661 ? 72.883  113.600 78.355  1.00 198.49 ? 661 TYR A CE2 1 
ATOM 5144 C CZ  . TYR A 1 661 ? 73.370  114.509 79.268  1.00 198.49 ? 661 TYR A CZ  1 
ATOM 5145 O OH  . TYR A 1 661 ? 73.273  115.855 79.007  1.00 198.49 ? 661 TYR A OH  1 
ATOM 5146 N N   . ALA A 1 662 ? 75.849  107.681 78.999  1.00 196.52 ? 662 ALA A N   1 
ATOM 5147 C CA  . ALA A 1 662 ? 75.854  106.249 78.730  1.00 196.52 ? 662 ALA A CA  1 
ATOM 5148 C C   . ALA A 1 662 ? 77.132  105.574 79.198  1.00 196.52 ? 662 ALA A C   1 
ATOM 5149 O O   . ALA A 1 662 ? 77.073  104.623 79.986  1.00 196.52 ? 662 ALA A O   1 
ATOM 5150 C CB  . ALA A 1 662 ? 75.644  105.994 77.228  1.00 196.52 ? 662 ALA A CB  1 
ATOM 5151 N N   . GLU A 1 663 ? 78.289  106.041 78.739  1.00 183.18 ? 663 GLU A N   1 
ATOM 5152 C CA  . GLU A 1 663 ? 79.574  105.511 79.171  1.00 183.18 ? 663 GLU A CA  1 
ATOM 5153 C C   . GLU A 1 663 ? 80.117  106.371 80.304  1.00 183.18 ? 663 GLU A C   1 
ATOM 5154 O O   . GLU A 1 663 ? 80.220  107.594 80.169  1.00 183.18 ? 663 GLU A O   1 
ATOM 5155 C CB  . GLU A 1 663 ? 80.572  105.467 78.014  1.00 183.18 ? 663 GLU A CB  1 
ATOM 5156 C CG  . GLU A 1 663 ? 81.976  105.082 78.441  1.00 183.18 ? 663 GLU A CG  1 
ATOM 5157 C CD  . GLU A 1 663 ? 82.012  103.763 79.186  1.00 183.18 ? 663 GLU A CD  1 
ATOM 5158 O OE1 . GLU A 1 663 ? 81.548  102.748 78.627  1.00 183.18 ? 663 GLU A OE1 1 
ATOM 5159 O OE2 . GLU A 1 663 ? 82.493  103.745 80.338  1.00 183.18 ? 663 GLU A OE2 1 
ATOM 5160 N N   . TYR A 1 664 ? 80.453  105.727 81.421  1.00 175.88 ? 664 TYR A N   1 
ATOM 5161 C CA  . TYR A 1 664 ? 80.960  106.442 82.584  1.00 175.88 ? 664 TYR A CA  1 
ATOM 5162 C C   . TYR A 1 664 ? 82.405  106.894 82.422  1.00 175.88 ? 664 TYR A C   1 
ATOM 5163 O O   . TYR A 1 664 ? 82.801  107.884 83.044  1.00 175.88 ? 664 TYR A O   1 
ATOM 5164 C CB  . TYR A 1 664 ? 80.829  105.567 83.834  1.00 175.88 ? 664 TYR A CB  1 
ATOM 5165 C CG  . TYR A 1 664 ? 81.230  104.124 83.621  1.00 175.88 ? 664 TYR A CG  1 
ATOM 5166 C CD1 . TYR A 1 664 ? 82.556  103.727 83.731  1.00 175.88 ? 664 TYR A CD1 1 
ATOM 5167 C CD2 . TYR A 1 664 ? 80.279  103.157 83.316  1.00 175.88 ? 664 TYR A CD2 1 
ATOM 5168 C CE1 . TYR A 1 664 ? 82.925  102.408 83.538  1.00 175.88 ? 664 TYR A CE1 1 
ATOM 5169 C CE2 . TYR A 1 664 ? 80.638  101.838 83.121  1.00 175.88 ? 664 TYR A CE2 1 
ATOM 5170 C CZ  . TYR A 1 664 ? 81.962  101.468 83.233  1.00 175.88 ? 664 TYR A CZ  1 
ATOM 5171 O OH  . TYR A 1 664 ? 82.322  100.154 83.041  1.00 175.88 ? 664 TYR A OH  1 
ATOM 5172 N N   . GLN A 1 665 ? 83.201  106.192 81.612  1.00 169.72 ? 665 GLN A N   1 
ATOM 5173 C CA  . GLN A 1 665 ? 84.625  106.505 81.524  1.00 169.72 ? 665 GLN A CA  1 
ATOM 5174 C C   . GLN A 1 665 ? 84.871  107.863 80.875  1.00 169.72 ? 665 GLN A C   1 
ATOM 5175 O O   . GLN A 1 665 ? 85.729  108.626 81.334  1.00 169.72 ? 665 GLN A O   1 
ATOM 5176 C CB  . GLN A 1 665 ? 85.357  105.397 80.766  1.00 169.72 ? 665 GLN A CB  1 
ATOM 5177 C CG  . GLN A 1 665 ? 85.436  104.084 81.536  1.00 169.72 ? 665 GLN A CG  1 
ATOM 5178 C CD  . GLN A 1 665 ? 86.069  102.964 80.736  1.00 169.72 ? 665 GLN A CD  1 
ATOM 5179 O OE1 . GLN A 1 665 ? 86.554  103.177 79.627  1.00 169.72 ? 665 GLN A OE1 1 
ATOM 5180 N NE2 . GLN A 1 665 ? 86.067  101.761 81.296  1.00 169.72 ? 665 GLN A NE2 1 
ATOM 5181 N N   . VAL A 1 666 ? 84.136  108.184 79.806  1.00 162.59 ? 666 VAL A N   1 
ATOM 5182 C CA  . VAL A 1 666 ? 84.355  109.454 79.114  1.00 162.59 ? 666 VAL A CA  1 
ATOM 5183 C C   . VAL A 1 666 ? 84.039  110.631 80.029  1.00 162.59 ? 666 VAL A C   1 
ATOM 5184 O O   . VAL A 1 666 ? 84.836  111.568 80.151  1.00 162.59 ? 666 VAL A O   1 
ATOM 5185 C CB  . VAL A 1 666 ? 83.532  109.513 77.813  1.00 162.59 ? 666 VAL A CB  1 
ATOM 5186 C CG1 . VAL A 1 666 ? 84.299  108.873 76.669  1.00 162.59 ? 666 VAL A CG1 1 
ATOM 5187 C CG2 . VAL A 1 666 ? 82.192  108.830 77.997  1.00 162.59 ? 666 VAL A CG2 1 
ATOM 5188 N N   . CYS A 1 667 ? 82.875  110.605 80.685  1.00 162.07 ? 667 CYS A N   1 
ATOM 5189 C CA  . CYS A 1 667 ? 82.531  111.687 81.601  1.00 162.07 ? 667 CYS A CA  1 
ATOM 5190 C C   . CYS A 1 667 ? 83.435  111.689 82.828  1.00 162.07 ? 667 CYS A C   1 
ATOM 5191 O O   . CYS A 1 667 ? 83.691  112.753 83.404  1.00 162.07 ? 667 CYS A O   1 
ATOM 5192 C CB  . CYS A 1 667 ? 81.059  111.594 82.007  1.00 162.07 ? 667 CYS A CB  1 
ATOM 5193 S SG  . CYS A 1 667 ? 80.551  110.011 82.701  1.00 162.07 ? 667 CYS A SG  1 
ATOM 5194 N N   . LEU A 1 668 ? 83.916  110.516 83.248  1.00 154.04 ? 668 LEU A N   1 
ATOM 5195 C CA  . LEU A 1 668 ? 84.912  110.464 84.315  1.00 154.04 ? 668 LEU A CA  1 
ATOM 5196 C C   . LEU A 1 668 ? 86.193  111.169 83.887  1.00 154.04 ? 668 LEU A C   1 
ATOM 5197 O O   . LEU A 1 668 ? 86.823  111.878 84.680  1.00 154.04 ? 668 LEU A O   1 
ATOM 5198 C CB  . LEU A 1 668 ? 85.192  109.009 84.698  1.00 154.04 ? 668 LEU A CB  1 
ATOM 5199 C CG  . LEU A 1 668 ? 85.544  108.683 86.153  1.00 154.04 ? 668 LEU A CG  1 
ATOM 5200 C CD1 . LEU A 1 668 ? 85.398  107.190 86.404  1.00 154.04 ? 668 LEU A CD1 1 
ATOM 5201 C CD2 . LEU A 1 668 ? 86.949  109.141 86.506  1.00 154.04 ? 668 LEU A CD2 1 
ATOM 5202 N N   . ALA A 1 669 ? 86.606  110.965 82.636  1.00 147.42 ? 669 ALA A N   1 
ATOM 5203 C CA  . ALA A 1 669 ? 87.718  111.729 82.087  1.00 147.42 ? 669 ALA A CA  1 
ATOM 5204 C C   . ALA A 1 669 ? 87.334  113.173 81.794  1.00 147.42 ? 669 ALA A C   1 
ATOM 5205 O O   . ALA A 1 669 ? 88.187  114.061 81.898  1.00 147.42 ? 669 ALA A O   1 
ATOM 5206 C CB  . ALA A 1 669 ? 88.244  111.059 80.818  1.00 147.42 ? 669 ALA A CB  1 
ATOM 5207 N N   . ALA A 1 670 ? 86.078  113.421 81.412  1.00 147.92 ? 670 ALA A N   1 
ATOM 5208 C CA  . ALA A 1 670 ? 85.652  114.782 81.099  1.00 147.92 ? 670 ALA A CA  1 
ATOM 5209 C C   . ALA A 1 670 ? 85.719  115.686 82.324  1.00 147.92 ? 670 ALA A C   1 
ATOM 5210 O O   . ALA A 1 670 ? 86.182  116.829 82.230  1.00 147.92 ? 670 ALA A O   1 
ATOM 5211 C CB  . ALA A 1 670 ? 84.239  114.769 80.518  1.00 147.92 ? 670 ALA A CB  1 
ATOM 5212 N N   . VAL A 1 671 ? 85.260  115.199 83.480  1.00 148.74 ? 671 VAL A N   1 
ATOM 5213 C CA  . VAL A 1 671 ? 85.338  116.012 84.690  1.00 148.74 ? 671 VAL A CA  1 
ATOM 5214 C C   . VAL A 1 671 ? 86.791  116.261 85.072  1.00 148.74 ? 671 VAL A C   1 
ATOM 5215 O O   . VAL A 1 671 ? 87.107  117.268 85.718  1.00 148.74 ? 671 VAL A O   1 
ATOM 5216 C CB  . VAL A 1 671 ? 84.545  115.366 85.843  1.00 148.74 ? 671 VAL A CB  1 
ATOM 5217 C CG1 . VAL A 1 671 ? 83.072  115.267 85.482  1.00 148.74 ? 671 VAL A CG1 1 
ATOM 5218 C CG2 . VAL A 1 671 ? 85.103  114.001 86.189  1.00 148.74 ? 671 VAL A CG2 1 
ATOM 5219 N N   . GLY A 1 672 ? 87.696  115.358 84.694  1.00 147.28 ? 672 GLY A N   1 
ATOM 5220 C CA  . GLY A 1 672 ? 89.112  115.646 84.841  1.00 147.28 ? 672 GLY A CA  1 
ATOM 5221 C C   . GLY A 1 672 ? 89.574  116.755 83.916  1.00 147.28 ? 672 GLY A C   1 
ATOM 5222 O O   . GLY A 1 672 ? 90.405  117.586 84.292  1.00 147.28 ? 672 GLY A O   1 
ATOM 5223 N N   . LEU A 1 673 ? 89.041  116.782 82.691  1.00 148.35 ? 673 LEU A N   1 
ATOM 5224 C CA  . LEU A 1 673 ? 89.443  117.801 81.726  1.00 148.35 ? 673 LEU A CA  1 
ATOM 5225 C C   . LEU A 1 673 ? 89.070  119.199 82.207  1.00 148.35 ? 673 LEU A C   1 
ATOM 5226 O O   . LEU A 1 673 ? 89.912  120.104 82.204  1.00 148.35 ? 673 LEU A O   1 
ATOM 5227 C CB  . LEU A 1 673 ? 88.808  117.511 80.365  1.00 148.35 ? 673 LEU A CB  1 
ATOM 5228 C CG  . LEU A 1 673 ? 89.659  117.750 79.112  1.00 148.35 ? 673 LEU A CG  1 
ATOM 5229 C CD1 . LEU A 1 673 ? 88.926  117.261 77.871  1.00 148.35 ? 673 LEU A CD1 1 
ATOM 5230 C CD2 . LEU A 1 673 ? 90.043  119.214 78.960  1.00 148.35 ? 673 LEU A CD2 1 
ATOM 5231 N N   . VAL A 1 674 ? 87.817  119.394 82.626  1.00 142.70 ? 674 VAL A N   1 
ATOM 5232 C CA  . VAL A 1 674 ? 87.416  120.696 83.149  1.00 142.70 ? 674 VAL A CA  1 
ATOM 5233 C C   . VAL A 1 674 ? 88.211  121.039 84.404  1.00 142.70 ? 674 VAL A C   1 
ATOM 5234 O O   . VAL A 1 674 ? 88.589  122.200 84.604  1.00 142.70 ? 674 VAL A O   1 
ATOM 5235 C CB  . VAL A 1 674 ? 85.897  120.741 83.404  1.00 142.70 ? 674 VAL A CB  1 
ATOM 5236 C CG1 . VAL A 1 674 ? 85.463  119.616 84.321  1.00 142.70 ? 674 VAL A CG1 1 
ATOM 5237 C CG2 . VAL A 1 674 ? 85.485  122.092 83.979  1.00 142.70 ? 674 VAL A CG2 1 
ATOM 5238 N N   . GLY A 1 675 ? 88.481  120.051 85.260  1.00 153.72 ? 675 GLY A N   1 
ATOM 5239 C CA  . GLY A 1 675 ? 89.370  120.288 86.385  1.00 153.72 ? 675 GLY A CA  1 
ATOM 5240 C C   . GLY A 1 675 ? 90.760  120.699 85.940  1.00 153.72 ? 675 GLY A C   1 
ATOM 5241 O O   . GLY A 1 675 ? 91.376  121.586 86.537  1.00 153.72 ? 675 GLY A O   1 
ATOM 5242 N N   . ASP A 1 676 ? 91.275  120.058 84.889  1.00 157.43 ? 676 ASP A N   1 
ATOM 5243 C CA  . ASP A 1 676 ? 92.561  120.462 84.332  1.00 157.43 ? 676 ASP A CA  1 
ATOM 5244 C C   . ASP A 1 676 ? 92.475  121.838 83.681  1.00 157.43 ? 676 ASP A C   1 
ATOM 5245 O O   . ASP A 1 676 ? 93.427  122.624 83.747  1.00 157.43 ? 676 ASP A O   1 
ATOM 5246 C CB  . ASP A 1 676 ? 93.051  119.417 83.330  1.00 157.43 ? 676 ASP A CB  1 
ATOM 5247 C CG  . ASP A 1 676 ? 93.445  118.113 83.997  1.00 157.43 ? 676 ASP A CG  1 
ATOM 5248 O OD1 . ASP A 1 676 ? 93.415  118.051 85.244  1.00 157.43 ? 676 ASP A OD1 1 
ATOM 5249 O OD2 . ASP A 1 676 ? 93.780  117.149 83.277  1.00 157.43 ? 676 ASP A OD2 1 
ATOM 5250 N N   . LEU A 1 677 ? 91.347  122.140 83.031  1.00 157.21 ? 677 LEU A N   1 
ATOM 5251 C CA  . LEU A 1 677 ? 91.185  123.449 82.405  1.00 157.21 ? 677 LEU A CA  1 
ATOM 5252 C C   . LEU A 1 677 ? 91.235  124.570 83.436  1.00 157.21 ? 677 LEU A C   1 
ATOM 5253 O O   . LEU A 1 677 ? 92.016  125.519 83.296  1.00 157.21 ? 677 LEU A O   1 
ATOM 5254 C CB  . LEU A 1 677 ? 89.871  123.500 81.625  1.00 157.21 ? 677 LEU A CB  1 
ATOM 5255 C CG  . LEU A 1 677 ? 89.811  122.727 80.306  1.00 157.21 ? 677 LEU A CG  1 
ATOM 5256 C CD1 . LEU A 1 677 ? 88.408  122.772 79.723  1.00 157.21 ? 677 LEU A CD1 1 
ATOM 5257 C CD2 . LEU A 1 677 ? 90.821  123.284 79.314  1.00 157.21 ? 677 LEU A CD2 1 
ATOM 5258 N N   . CYS A 1 678 ? 90.421  124.470 84.489  1.00 172.41 ? 678 CYS A N   1 
ATOM 5259 C CA  . CYS A 1 678 ? 90.358  125.537 85.483  1.00 172.41 ? 678 CYS A CA  1 
ATOM 5260 C C   . CYS A 1 678 ? 91.657  125.626 86.275  1.00 172.41 ? 678 CYS A C   1 
ATOM 5261 O O   . CYS A 1 678 ? 92.035  126.703 86.750  1.00 172.41 ? 678 CYS A O   1 
ATOM 5262 C CB  . CYS A 1 678 ? 89.167  125.315 86.415  1.00 172.41 ? 678 CYS A CB  1 
ATOM 5263 S SG  . CYS A 1 678 ? 89.284  123.834 87.443  1.00 172.41 ? 678 CYS A SG  1 
ATOM 5264 N N   . ARG A 1 679 ? 92.352  124.496 86.435  1.00 165.02 ? 679 ARG A N   1 
ATOM 5265 C CA  . ARG A 1 679 ? 93.603  124.494 87.184  1.00 165.02 ? 679 ARG A CA  1 
ATOM 5266 C C   . ARG A 1 679 ? 94.699  125.271 86.463  1.00 165.02 ? 679 ARG A C   1 
ATOM 5267 O O   . ARG A 1 679 ? 95.666  125.707 87.097  1.00 165.02 ? 679 ARG A O   1 
ATOM 5268 C CB  . ARG A 1 679 ? 94.052  123.056 87.447  1.00 165.02 ? 679 ARG A CB  1 
ATOM 5269 C CG  . ARG A 1 679 ? 94.921  122.893 88.683  1.00 165.02 ? 679 ARG A CG  1 
ATOM 5270 C CD  . ARG A 1 679 ? 95.198  121.426 88.998  1.00 165.02 ? 679 ARG A CD  1 
ATOM 5271 N NE  . ARG A 1 679 ? 93.975  120.659 89.211  1.00 165.02 ? 679 ARG A NE  1 
ATOM 5272 C CZ  . ARG A 1 679 ? 93.479  119.783 88.347  1.00 165.02 ? 679 ARG A CZ  1 
ATOM 5273 N NH1 . ARG A 1 679 ? 94.084  119.526 87.199  1.00 165.02 ? 679 ARG A NH1 1 
ATOM 5274 N NH2 . ARG A 1 679 ? 92.349  119.147 88.644  1.00 165.02 ? 679 ARG A NH2 1 
ATOM 5275 N N   . ALA A 1 680 ? 94.571  125.455 85.147  1.00 158.21 ? 680 ALA A N   1 
ATOM 5276 C CA  . ALA A 1 680 ? 95.605  126.156 84.393  1.00 158.21 ? 680 ALA A CA  1 
ATOM 5277 C C   . ALA A 1 680 ? 95.120  127.517 83.904  1.00 158.21 ? 680 ALA A C   1 
ATOM 5278 O O   . ALA A 1 680 ? 95.858  128.506 83.969  1.00 158.21 ? 680 ALA A O   1 
ATOM 5279 C CB  . ALA A 1 680 ? 96.068  125.298 83.215  1.00 158.21 ? 680 ALA A CB  1 
ATOM 5280 N N   . LEU A 1 681 ? 93.887  127.584 83.400  1.00 172.92 ? 681 LEU A N   1 
ATOM 5281 C CA  . LEU A 1 681 ? 93.335  128.834 82.891  1.00 172.92 ? 681 LEU A CA  1 
ATOM 5282 C C   . LEU A 1 681 ? 93.092  129.870 83.982  1.00 172.92 ? 681 LEU A C   1 
ATOM 5283 O O   . LEU A 1 681 ? 92.969  131.058 83.663  1.00 172.92 ? 681 LEU A O   1 
ATOM 5284 C CB  . LEU A 1 681 ? 92.033  128.564 82.133  1.00 172.92 ? 681 LEU A CB  1 
ATOM 5285 C CG  . LEU A 1 681 ? 92.182  127.665 80.902  1.00 172.92 ? 681 LEU A CG  1 
ATOM 5286 C CD1 . LEU A 1 681 ? 90.848  127.467 80.203  1.00 172.92 ? 681 LEU A CD1 1 
ATOM 5287 C CD2 . LEU A 1 681 ? 93.216  128.228 79.939  1.00 172.92 ? 681 LEU A CD2 1 
ATOM 5288 N N   . GLN A 1 682 ? 93.014  129.448 85.246  1.00 175.20 ? 682 GLN A N   1 
ATOM 5289 C CA  . GLN A 1 682 ? 92.880  130.340 86.403  1.00 175.20 ? 682 GLN A CA  1 
ATOM 5290 C C   . GLN A 1 682 ? 91.589  131.140 86.263  1.00 175.20 ? 682 GLN A C   1 
ATOM 5291 O O   . GLN A 1 682 ? 90.508  130.527 86.221  1.00 175.20 ? 682 GLN A O   1 
ATOM 5292 C CB  . GLN A 1 682 ? 94.163  131.165 86.536  1.00 175.20 ? 682 GLN A CB  1 
ATOM 5293 C CG  . GLN A 1 682 ? 95.416  130.334 86.759  1.00 175.20 ? 682 GLN A CG  1 
ATOM 5294 C CD  . GLN A 1 682 ? 95.408  129.605 88.090  1.00 175.20 ? 682 GLN A CD  1 
ATOM 5295 O OE1 . GLN A 1 682 ? 95.961  128.513 88.215  1.00 175.20 ? 682 GLN A OE1 1 
ATOM 5296 N NE2 . GLN A 1 682 ? 94.786  130.212 89.094  1.00 175.20 ? 682 GLN A NE2 1 
ATOM 5297 N N   . SER A 1 683 ? 91.636  132.468 86.194  1.00 184.55 ? 683 SER A N   1 
ATOM 5298 C CA  . SER A 1 683 ? 90.444  133.304 86.230  1.00 184.55 ? 683 SER A CA  1 
ATOM 5299 C C   . SER A 1 683 ? 89.869  133.587 84.847  1.00 184.55 ? 683 SER A C   1 
ATOM 5300 O O   . SER A 1 683 ? 88.911  134.359 84.736  1.00 184.55 ? 683 SER A O   1 
ATOM 5301 C CB  . SER A 1 683 ? 90.753  134.624 86.941  1.00 184.55 ? 683 SER A CB  1 
ATOM 5302 O OG  . SER A 1 683 ? 91.773  135.338 86.265  1.00 184.55 ? 683 SER A OG  1 
ATOM 5303 N N   . ASN A 1 684 ? 90.426  132.988 83.797  1.00 181.76 ? 684 ASN A N   1 
ATOM 5304 C CA  . ASN A 1 684 ? 89.923  133.172 82.443  1.00 181.76 ? 684 ASN A CA  1 
ATOM 5305 C C   . ASN A 1 684 ? 88.844  132.165 82.071  1.00 181.76 ? 684 ASN A C   1 
ATOM 5306 O O   . ASN A 1 684 ? 88.353  132.193 80.938  1.00 181.76 ? 684 ASN A O   1 
ATOM 5307 C CB  . ASN A 1 684 ? 91.075  133.089 81.437  1.00 181.76 ? 684 ASN A CB  1 
ATOM 5308 C CG  . ASN A 1 684 ? 92.054  134.236 81.579  1.00 181.76 ? 684 ASN A CG  1 
ATOM 5309 O OD1 . ASN A 1 684 ? 91.900  135.279 80.945  1.00 181.76 ? 684 ASN A OD1 1 
ATOM 5310 N ND2 . ASN A 1 684 ? 93.067  134.050 82.417  1.00 181.76 ? 684 ASN A ND2 1 
ATOM 5311 N N   . ILE A 1 685 ? 88.466  131.277 82.996  1.00 183.35 ? 685 ILE A N   1 
ATOM 5312 C CA  . ILE A 1 685 ? 87.413  130.297 82.742  1.00 183.35 ? 685 ILE A CA  1 
ATOM 5313 C C   . ILE A 1 685 ? 86.032  130.818 83.124  1.00 183.35 ? 685 ILE A C   1 
ATOM 5314 O O   . ILE A 1 685 ? 85.042  130.081 82.991  1.00 183.35 ? 685 ILE A O   1 
ATOM 5315 C CB  . ILE A 1 685 ? 87.732  128.983 83.488  1.00 183.35 ? 685 ILE A CB  1 
ATOM 5316 C CG1 . ILE A 1 685 ? 87.021  127.791 82.840  1.00 183.35 ? 685 ILE A CG1 1 
ATOM 5317 C CG2 . ILE A 1 685 ? 87.377  129.100 84.964  1.00 183.35 ? 685 ILE A CG2 1 
ATOM 5318 C CD1 . ILE A 1 685 ? 87.372  127.587 81.385  1.00 183.35 ? 685 ILE A CD1 1 
ATOM 5319 N N   . ILE A 1 686 ? 85.934  132.067 83.596  1.00 186.83 ? 686 ILE A N   1 
ATOM 5320 C CA  . ILE A 1 686 ? 84.638  132.592 84.042  1.00 186.83 ? 686 ILE A CA  1 
ATOM 5321 C C   . ILE A 1 686 ? 83.579  132.550 82.951  1.00 186.83 ? 686 ILE A C   1 
ATOM 5322 O O   . ILE A 1 686 ? 82.468  132.068 83.220  1.00 186.83 ? 686 ILE A O   1 
ATOM 5323 C CB  . ILE A 1 686 ? 84.818  133.992 84.649  1.00 186.83 ? 686 ILE A CB  1 
ATOM 5324 C CG1 . ILE A 1 686 ? 85.836  133.952 85.788  1.00 186.83 ? 686 ILE A CG1 1 
ATOM 5325 C CG2 . ILE A 1 686 ? 83.485  134.536 85.140  1.00 186.83 ? 686 ILE A CG2 1 
ATOM 5326 C CD1 . ILE A 1 686 ? 86.056  135.292 86.456  1.00 186.83 ? 686 ILE A CD1 1 
ATOM 5327 N N   . PRO A 1 687 ? 83.818  133.031 81.722  1.00 185.62 ? 687 PRO A N   1 
ATOM 5328 C CA  . PRO A 1 687 ? 82.757  132.961 80.703  1.00 185.62 ? 687 PRO A CA  1 
ATOM 5329 C C   . PRO A 1 687 ? 82.369  131.545 80.316  1.00 185.62 ? 687 PRO A C   1 
ATOM 5330 O O   . PRO A 1 687 ? 81.260  131.346 79.803  1.00 185.62 ? 687 PRO A O   1 
ATOM 5331 C CB  . PRO A 1 687 ? 83.358  133.719 79.511  1.00 185.62 ? 687 PRO A CB  1 
ATOM 5332 C CG  . PRO A 1 687 ? 84.825  133.629 79.712  1.00 185.62 ? 687 PRO A CG  1 
ATOM 5333 C CD  . PRO A 1 687 ? 85.020  133.703 81.194  1.00 185.62 ? 687 PRO A CD  1 
ATOM 5334 N N   . PHE A 1 688 ? 83.235  130.560 80.542  1.00 188.35 ? 688 PHE A N   1 
ATOM 5335 C CA  . PHE A 1 688 ? 82.951  129.175 80.194  1.00 188.35 ? 688 PHE A CA  1 
ATOM 5336 C C   . PHE A 1 688 ? 82.360  128.383 81.352  1.00 188.35 ? 688 PHE A C   1 
ATOM 5337 O O   . PHE A 1 688 ? 81.933  127.242 81.151  1.00 188.35 ? 688 PHE A O   1 
ATOM 5338 C CB  . PHE A 1 688 ? 84.226  128.486 79.696  1.00 188.35 ? 688 PHE A CB  1 
ATOM 5339 C CG  . PHE A 1 688 ? 85.007  129.300 78.704  1.00 188.35 ? 688 PHE A CG  1 
ATOM 5340 C CD1 . PHE A 1 688 ? 84.672  129.289 77.360  1.00 188.35 ? 688 PHE A CD1 1 
ATOM 5341 C CD2 . PHE A 1 688 ? 86.081  130.073 79.115  1.00 188.35 ? 688 PHE A CD2 1 
ATOM 5342 C CE1 . PHE A 1 688 ? 85.391  130.036 76.447  1.00 188.35 ? 688 PHE A CE1 1 
ATOM 5343 C CE2 . PHE A 1 688 ? 86.803  130.821 78.207  1.00 188.35 ? 688 PHE A CE2 1 
ATOM 5344 C CZ  . PHE A 1 688 ? 86.458  130.803 76.871  1.00 188.35 ? 688 PHE A CZ  1 
ATOM 5345 N N   . CYS A 1 689 ? 82.325  128.957 82.556  1.00 197.60 ? 689 CYS A N   1 
ATOM 5346 C CA  . CYS A 1 689 ? 81.805  128.244 83.717  1.00 197.60 ? 689 CYS A CA  1 
ATOM 5347 C C   . CYS A 1 689 ? 80.292  128.070 83.662  1.00 197.60 ? 689 CYS A C   1 
ATOM 5348 O O   . CYS A 1 689 ? 79.774  127.057 84.146  1.00 197.60 ? 689 CYS A O   1 
ATOM 5349 C CB  . CYS A 1 689 ? 82.200  128.978 84.999  1.00 197.60 ? 689 CYS A CB  1 
ATOM 5350 S SG  . CYS A 1 689 ? 81.680  128.157 86.522  1.00 197.60 ? 689 CYS A SG  1 
ATOM 5351 N N   . ASP A 1 690 ? 79.573  129.038 83.090  1.00 203.87 ? 690 ASP A N   1 
ATOM 5352 C CA  . ASP A 1 690 ? 78.114  128.978 83.087  1.00 203.87 ? 690 ASP A CA  1 
ATOM 5353 C C   . ASP A 1 690 ? 77.602  127.789 82.281  1.00 203.87 ? 690 ASP A C   1 
ATOM 5354 O O   . ASP A 1 690 ? 76.654  127.113 82.697  1.00 203.87 ? 690 ASP A O   1 
ATOM 5355 C CB  . ASP A 1 690 ? 77.538  130.283 82.537  1.00 203.87 ? 690 ASP A CB  1 
ATOM 5356 C CG  . ASP A 1 690 ? 78.043  131.504 83.283  1.00 203.87 ? 690 ASP A CG  1 
ATOM 5357 O OD1 . ASP A 1 690 ? 78.357  131.383 84.486  1.00 203.87 ? 690 ASP A OD1 1 
ATOM 5358 O OD2 . ASP A 1 690 ? 78.126  132.587 82.666  1.00 203.87 ? 690 ASP A OD2 1 
ATOM 5359 N N   . GLU A 1 691 ? 78.210  127.524 81.123  1.00 197.69 ? 691 GLU A N   1 
ATOM 5360 C CA  . GLU A 1 691 ? 77.730  126.446 80.263  1.00 197.69 ? 691 GLU A CA  1 
ATOM 5361 C C   . GLU A 1 691 ? 77.918  125.081 80.916  1.00 197.69 ? 691 GLU A C   1 
ATOM 5362 O O   . GLU A 1 691 ? 76.993  124.260 80.927  1.00 197.69 ? 691 GLU A O   1 
ATOM 5363 C CB  . GLU A 1 691 ? 78.447  126.491 78.913  1.00 197.69 ? 691 GLU A CB  1 
ATOM 5364 C CG  . GLU A 1 691 ? 78.291  127.801 78.152  1.00 197.69 ? 691 GLU A CG  1 
ATOM 5365 C CD  . GLU A 1 691 ? 79.306  128.854 78.566  1.00 197.69 ? 691 GLU A CD  1 
ATOM 5366 O OE1 . GLU A 1 691 ? 79.653  128.919 79.765  1.00 197.69 ? 691 GLU A OE1 1 
ATOM 5367 O OE2 . GLU A 1 691 ? 79.762  129.614 77.687  1.00 197.69 ? 691 GLU A OE2 1 
ATOM 5368 N N   . VAL A 1 692 ? 79.107  124.821 81.464  1.00 201.23 ? 692 VAL A N   1 
ATOM 5369 C CA  . VAL A 1 692 ? 79.381  123.510 82.043  1.00 201.23 ? 692 VAL A CA  1 
ATOM 5370 C C   . VAL A 1 692 ? 78.591  123.304 83.330  1.00 201.23 ? 692 VAL A C   1 
ATOM 5371 O O   . VAL A 1 692 ? 78.075  122.207 83.579  1.00 201.23 ? 692 VAL A O   1 
ATOM 5372 C CB  . VAL A 1 692 ? 80.897  123.331 82.265  1.00 201.23 ? 692 VAL A CB  1 
ATOM 5373 C CG1 . VAL A 1 692 ? 81.476  124.502 83.046  1.00 201.23 ? 692 VAL A CG1 1 
ATOM 5374 C CG2 . VAL A 1 692 ? 81.185  122.015 82.972  1.00 201.23 ? 692 VAL A CG2 1 
ATOM 5375 N N   . MET A 1 693 ? 78.475  124.342 84.162  1.00 194.88 ? 693 MET A N   1 
ATOM 5376 C CA  . MET A 1 693 ? 77.846  124.182 85.470  1.00 194.88 ? 693 MET A CA  1 
ATOM 5377 C C   . MET A 1 693 ? 76.378  123.791 85.348  1.00 194.88 ? 693 MET A C   1 
ATOM 5378 O O   . MET A 1 693 ? 75.901  122.921 86.085  1.00 194.88 ? 693 MET A O   1 
ATOM 5379 C CB  . MET A 1 693 ? 77.993  125.467 86.282  1.00 194.88 ? 693 MET A CB  1 
ATOM 5380 C CG  . MET A 1 693 ? 77.723  125.278 87.757  1.00 194.88 ? 693 MET A CG  1 
ATOM 5381 S SD  . MET A 1 693 ? 78.778  123.992 88.446  1.00 194.88 ? 693 MET A SD  1 
ATOM 5382 C CE  . MET A 1 693 ? 78.073  123.825 90.079  1.00 194.88 ? 693 MET A CE  1 
ATOM 5383 N N   . GLN A 1 694 ? 75.643  124.428 84.431  1.00 202.95 ? 694 GLN A N   1 
ATOM 5384 C CA  . GLN A 1 694 ? 74.238  124.079 84.240  1.00 202.95 ? 694 GLN A CA  1 
ATOM 5385 C C   . GLN A 1 694 ? 74.084  122.626 83.809  1.00 202.95 ? 694 GLN A C   1 
ATOM 5386 O O   . GLN A 1 694 ? 73.235  121.899 84.337  1.00 202.95 ? 694 GLN A O   1 
ATOM 5387 C CB  . GLN A 1 694 ? 73.600  125.017 83.215  1.00 202.95 ? 694 GLN A CB  1 
ATOM 5388 C CG  . GLN A 1 694 ? 72.309  124.495 82.598  1.00 202.95 ? 694 GLN A CG  1 
ATOM 5389 C CD  . GLN A 1 694 ? 71.209  124.268 83.619  1.00 202.95 ? 694 GLN A CD  1 
ATOM 5390 O OE1 . GLN A 1 694 ? 71.161  124.925 84.660  1.00 202.95 ? 694 GLN A OE1 1 
ATOM 5391 N NE2 . GLN A 1 694 ? 70.316  123.330 83.324  1.00 202.95 ? 694 GLN A NE2 1 
ATOM 5392 N N   . LEU A 1 695 ? 74.899  122.188 82.847  1.00 198.45 ? 695 LEU A N   1 
ATOM 5393 C CA  . LEU A 1 695 ? 74.873  120.791 82.428  1.00 198.45 ? 695 LEU A CA  1 
ATOM 5394 C C   . LEU A 1 695 ? 75.353  119.862 83.535  1.00 198.45 ? 695 LEU A C   1 
ATOM 5395 O O   . LEU A 1 695 ? 74.825  118.754 83.686  1.00 198.45 ? 695 LEU A O   1 
ATOM 5396 C CB  . LEU A 1 695 ? 75.729  120.613 81.175  1.00 198.45 ? 695 LEU A CB  1 
ATOM 5397 C CG  . LEU A 1 695 ? 75.921  119.193 80.644  1.00 198.45 ? 695 LEU A CG  1 
ATOM 5398 C CD1 . LEU A 1 695 ? 74.609  118.621 80.139  1.00 198.45 ? 695 LEU A CD1 1 
ATOM 5399 C CD2 . LEU A 1 695 ? 76.974  119.179 79.549  1.00 198.45 ? 695 LEU A CD2 1 
ATOM 5400 N N   . LEU A 1 696 ? 76.349  120.294 84.312  1.00 195.06 ? 696 LEU A N   1 
ATOM 5401 C CA  . LEU A 1 696 ? 76.910  119.442 85.355  1.00 195.06 ? 696 LEU A CA  1 
ATOM 5402 C C   . LEU A 1 696 ? 75.882  119.140 86.439  1.00 195.06 ? 696 LEU A C   1 
ATOM 5403 O O   . LEU A 1 696 ? 75.812  118.010 86.938  1.00 195.06 ? 696 LEU A O   1 
ATOM 5404 C CB  . LEU A 1 696 ? 78.150  120.105 85.951  1.00 195.06 ? 696 LEU A CB  1 
ATOM 5405 C CG  . LEU A 1 696 ? 79.183  119.213 86.636  1.00 195.06 ? 696 LEU A CG  1 
ATOM 5406 C CD1 . LEU A 1 696 ? 79.470  117.980 85.797  1.00 195.06 ? 696 LEU A CD1 1 
ATOM 5407 C CD2 . LEU A 1 696 ? 80.455  120.007 86.860  1.00 195.06 ? 696 LEU A CD2 1 
ATOM 5408 N N   . LEU A 1 697 ? 75.080  120.137 86.820  1.00 195.09 ? 697 LEU A N   1 
ATOM 5409 C CA  . LEU A 1 697 ? 74.043  119.913 87.823  1.00 195.09 ? 697 LEU A CA  1 
ATOM 5410 C C   . LEU A 1 697 ? 73.001  118.916 87.331  1.00 195.09 ? 697 LEU A C   1 
ATOM 5411 O O   . LEU A 1 697 ? 72.408  118.185 88.133  1.00 195.09 ? 697 LEU A O   1 
ATOM 5412 C CB  . LEU A 1 697 ? 73.383  121.239 88.199  1.00 195.09 ? 697 LEU A CB  1 
ATOM 5413 C CG  . LEU A 1 697 ? 74.287  122.268 88.878  1.00 195.09 ? 697 LEU A CG  1 
ATOM 5414 C CD1 . LEU A 1 697 ? 73.534  123.566 89.123  1.00 195.09 ? 697 LEU A CD1 1 
ATOM 5415 C CD2 . LEU A 1 697 ? 74.845  121.713 90.179  1.00 195.09 ? 697 LEU A CD2 1 
ATOM 5416 N N   . GLU A 1 698 ? 72.761  118.876 86.018  1.00 206.38 ? 698 GLU A N   1 
ATOM 5417 C CA  . GLU A 1 698 ? 71.827  117.903 85.463  1.00 206.38 ? 698 GLU A CA  1 
ATOM 5418 C C   . GLU A 1 698 ? 72.298  116.474 85.698  1.00 206.38 ? 698 GLU A C   1 
ATOM 5419 O O   . GLU A 1 698 ? 71.473  115.581 85.924  1.00 206.38 ? 698 GLU A O   1 
ATOM 5420 C CB  . GLU A 1 698 ? 71.628  118.155 83.969  1.00 206.38 ? 698 GLU A CB  1 
ATOM 5421 C CG  . GLU A 1 698 ? 71.121  119.550 83.634  1.00 206.38 ? 698 GLU A CG  1 
ATOM 5422 C CD  . GLU A 1 698 ? 69.698  119.791 84.106  1.00 206.38 ? 698 GLU A CD  1 
ATOM 5423 O OE1 . GLU A 1 698 ? 68.962  118.805 84.320  1.00 206.38 ? 698 GLU A OE1 1 
ATOM 5424 O OE2 . GLU A 1 698 ? 69.314  120.970 84.261  1.00 206.38 ? 698 GLU A OE2 1 
ATOM 5425 N N   . ASN A 1 699 ? 73.610  116.236 85.636  1.00 199.80 ? 699 ASN A N   1 
ATOM 5426 C CA  . ASN A 1 699 ? 74.132  114.898 85.892  1.00 199.80 ? 699 ASN A CA  1 
ATOM 5427 C C   . ASN A 1 699 ? 73.834  114.453 87.318  1.00 199.80 ? 699 ASN A C   1 
ATOM 5428 O O   . ASN A 1 699 ? 73.605  113.263 87.568  1.00 199.80 ? 699 ASN A O   1 
ATOM 5429 C CB  . ASN A 1 699 ? 75.636  114.863 85.624  1.00 199.80 ? 699 ASN A CB  1 
ATOM 5430 C CG  . ASN A 1 699 ? 75.995  115.390 84.251  1.00 199.80 ? 699 ASN A CG  1 
ATOM 5431 O OD1 . ASN A 1 699 ? 76.813  116.300 84.118  1.00 199.80 ? 699 ASN A OD1 1 
ATOM 5432 N ND2 . ASN A 1 699 ? 75.383  114.821 83.220  1.00 199.80 ? 699 ASN A ND2 1 
ATOM 5433 N N   . LEU A 1 700 ? 73.841  115.393 88.266  1.00 200.71 ? 700 LEU A N   1 
ATOM 5434 C CA  . LEU A 1 700 ? 73.539  115.051 89.652  1.00 200.71 ? 700 LEU A CA  1 
ATOM 5435 C C   . LEU A 1 700 ? 72.114  114.532 89.798  1.00 200.71 ? 700 LEU A C   1 
ATOM 5436 O O   . LEU A 1 700 ? 71.879  113.534 90.489  1.00 200.71 ? 700 LEU A O   1 
ATOM 5437 C CB  . LEU A 1 700 ? 73.753  116.267 90.551  1.00 200.71 ? 700 LEU A CB  1 
ATOM 5438 C CG  . LEU A 1 700 ? 75.134  116.920 90.530  1.00 200.71 ? 700 LEU A CG  1 
ATOM 5439 C CD1 . LEU A 1 700 ? 75.137  118.157 91.411  1.00 200.71 ? 700 LEU A CD1 1 
ATOM 5440 C CD2 . LEU A 1 700 ? 76.195  115.935 90.982  1.00 200.71 ? 700 LEU A CD2 1 
ATOM 5441 N N   . GLY A 1 701 ? 71.153  115.197 89.153  1.00 215.58 ? 701 GLY A N   1 
ATOM 5442 C CA  . GLY A 1 701 ? 69.766  114.782 89.280  1.00 215.58 ? 701 GLY A CA  1 
ATOM 5443 C C   . GLY A 1 701 ? 69.505  113.408 88.693  1.00 215.58 ? 701 GLY A C   1 
ATOM 5444 O O   . GLY A 1 701 ? 68.799  112.592 89.292  1.00 215.58 ? 701 GLY A O   1 
ATOM 5445 N N   . ASN A 1 702 ? 70.059  113.137 87.516  1.00 216.04 ? 702 ASN A N   1 
ATOM 5446 C CA  . ASN A 1 702 ? 69.884  111.842 86.876  1.00 216.04 ? 702 ASN A CA  1 
ATOM 5447 C C   . ASN A 1 702 ? 70.635  110.769 87.654  1.00 216.04 ? 702 ASN A C   1 
ATOM 5448 O O   . ASN A 1 702 ? 71.823  110.925 87.955  1.00 216.04 ? 702 ASN A O   1 
ATOM 5449 C CB  . ASN A 1 702 ? 70.374  111.893 85.430  1.00 216.04 ? 702 ASN A CB  1 
ATOM 5450 C CG  . ASN A 1 702 ? 70.267  110.555 84.731  1.00 216.04 ? 702 ASN A CG  1 
ATOM 5451 O OD1 . ASN A 1 702 ? 71.212  109.763 84.732  1.00 216.04 ? 702 ASN A OD1 1 
ATOM 5452 N ND2 . ASN A 1 702 ? 69.113  110.291 84.130  1.00 216.04 ? 702 ASN A ND2 1 
ATOM 5453 N N   . GLU A 1 703 ? 69.942  109.678 87.974  1.00 220.35 ? 703 GLU A N   1 
ATOM 5454 C CA  . GLU A 1 703 ? 70.537  108.552 88.681  1.00 220.35 ? 703 GLU A CA  1 
ATOM 5455 C C   . GLU A 1 703 ? 70.766  107.354 87.771  1.00 220.35 ? 703 GLU A C   1 
ATOM 5456 O O   . GLU A 1 703 ? 71.181  106.293 88.249  1.00 220.35 ? 703 GLU A O   1 
ATOM 5457 C CB  . GLU A 1 703 ? 69.663  108.150 89.872  1.00 220.35 ? 703 GLU A CB  1 
ATOM 5458 C CG  . GLU A 1 703 ? 69.457  109.259 90.893  1.00 220.35 ? 703 GLU A CG  1 
ATOM 5459 C CD  . GLU A 1 703 ? 70.754  109.710 91.536  1.00 220.35 ? 703 GLU A CD  1 
ATOM 5460 O OE1 . GLU A 1 703 ? 71.674  108.877 91.678  1.00 220.35 ? 703 GLU A OE1 1 
ATOM 5461 O OE2 . GLU A 1 703 ? 70.855  110.901 91.898  1.00 220.35 ? 703 GLU A OE2 1 
ATOM 5462 N N   . ASN A 1 704 ? 70.504  107.496 86.471  1.00 217.39 ? 704 ASN A N   1 
ATOM 5463 C CA  . ASN A 1 704 ? 70.764  106.428 85.517  1.00 217.39 ? 704 ASN A CA  1 
ATOM 5464 C C   . ASN A 1 704 ? 72.247  106.243 85.228  1.00 217.39 ? 704 ASN A C   1 
ATOM 5465 O O   . ASN A 1 704 ? 72.630  105.204 84.680  1.00 217.39 ? 704 ASN A O   1 
ATOM 5466 C CB  . ASN A 1 704 ? 70.013  106.697 84.210  1.00 217.39 ? 704 ASN A CB  1 
ATOM 5467 C CG  . ASN A 1 704 ? 68.516  106.840 84.417  1.00 217.39 ? 704 ASN A CG  1 
ATOM 5468 O OD1 . ASN A 1 704 ? 67.929  107.874 84.096  1.00 217.39 ? 704 ASN A OD1 1 
ATOM 5469 N ND2 . ASN A 1 704 ? 67.891  105.800 84.956  1.00 217.39 ? 704 ASN A ND2 1 
ATOM 5470 N N   . VAL A 1 705 ? 73.085  107.218 85.581  1.00 208.56 ? 705 VAL A N   1 
ATOM 5471 C CA  . VAL A 1 705 ? 74.526  107.127 85.375  1.00 208.56 ? 705 VAL A CA  1 
ATOM 5472 C C   . VAL A 1 705 ? 75.115  106.124 86.359  1.00 208.56 ? 705 VAL A C   1 
ATOM 5473 O O   . VAL A 1 705 ? 74.464  105.741 87.337  1.00 208.56 ? 705 VAL A O   1 
ATOM 5474 C CB  . VAL A 1 705 ? 75.199  108.504 85.523  1.00 208.56 ? 705 VAL A CB  1 
ATOM 5475 C CG1 . VAL A 1 705 ? 74.639  109.481 84.502  1.00 208.56 ? 705 VAL A CG1 1 
ATOM 5476 C CG2 . VAL A 1 705 ? 75.016  109.036 86.937  1.00 208.56 ? 705 VAL A CG2 1 
ATOM 5477 N N   . HIS A 1 706 ? 76.347  105.693 86.105  1.00 196.29 ? 706 HIS A N   1 
ATOM 5478 C CA  . HIS A 1 706 ? 76.997  104.724 86.974  1.00 196.29 ? 706 HIS A CA  1 
ATOM 5479 C C   . HIS A 1 706 ? 77.301  105.337 88.338  1.00 196.29 ? 706 HIS A C   1 
ATOM 5480 O O   . HIS A 1 706 ? 77.474  106.551 88.476  1.00 196.29 ? 706 HIS A O   1 
ATOM 5481 C CB  . HIS A 1 706 ? 78.284  104.211 86.330  1.00 196.29 ? 706 HIS A CB  1 
ATOM 5482 C CG  . HIS A 1 706 ? 78.782  102.926 86.913  1.00 196.29 ? 706 HIS A CG  1 
ATOM 5483 N ND1 . HIS A 1 706 ? 79.659  102.881 87.975  1.00 196.29 ? 706 HIS A ND1 1 
ATOM 5484 C CD2 . HIS A 1 706 ? 78.528  101.639 86.580  1.00 196.29 ? 706 HIS A CD2 1 
ATOM 5485 C CE1 . HIS A 1 706 ? 79.923  101.621 88.272  1.00 196.29 ? 706 HIS A CE1 1 
ATOM 5486 N NE2 . HIS A 1 706 ? 79.249  100.847 87.440  1.00 196.29 ? 706 HIS A NE2 1 
ATOM 5487 N N   . ARG A 1 707 ? 77.358  104.477 89.358  1.00 206.42 ? 707 ARG A N   1 
ATOM 5488 C CA  . ARG A 1 707 ? 77.603  104.953 90.715  1.00 206.42 ? 707 ARG A CA  1 
ATOM 5489 C C   . ARG A 1 707 ? 79.021  105.488 90.885  1.00 206.42 ? 707 ARG A C   1 
ATOM 5490 O O   . ARG A 1 707 ? 79.252  106.370 91.721  1.00 206.42 ? 707 ARG A O   1 
ATOM 5491 C CB  . ARG A 1 707 ? 77.337  103.835 91.724  1.00 206.42 ? 707 ARG A CB  1 
ATOM 5492 C CG  . ARG A 1 707 ? 78.333  102.688 91.661  1.00 206.42 ? 707 ARG A CG  1 
ATOM 5493 C CD  . ARG A 1 707 ? 78.286  101.840 92.922  1.00 206.42 ? 707 ARG A CD  1 
ATOM 5494 N NE  . ARG A 1 707 ? 79.476  101.010 93.063  1.00 206.42 ? 707 ARG A NE  1 
ATOM 5495 C CZ  . ARG A 1 707 ? 79.733  100.242 94.112  1.00 206.42 ? 707 ARG A CZ  1 
ATOM 5496 N NH1 . ARG A 1 707 ? 78.897  100.165 95.134  1.00 206.42 ? 707 ARG A NH1 1 
ATOM 5497 N NH2 . ARG A 1 707 ? 80.860  99.534  94.138  1.00 206.42 ? 707 ARG A NH2 1 
ATOM 5498 N N   . SER A 1 708 ? 79.980  104.968 90.116  1.00 190.38 ? 708 SER A N   1 
ATOM 5499 C CA  . SER A 1 708 ? 81.375  105.362 90.269  1.00 190.38 ? 708 SER A CA  1 
ATOM 5500 C C   . SER A 1 708 ? 81.643  106.800 89.845  1.00 190.38 ? 708 SER A C   1 
ATOM 5501 O O   . SER A 1 708 ? 82.520  107.448 90.427  1.00 190.38 ? 708 SER A O   1 
ATOM 5502 C CB  . SER A 1 708 ? 82.276  104.420 89.469  1.00 190.38 ? 708 SER A CB  1 
ATOM 5503 O OG  . SER A 1 708 ? 81.936  104.442 88.093  1.00 190.38 ? 708 SER A OG  1 
ATOM 5504 N N   . VAL A 1 709 ? 80.931  107.306 88.837  1.00 181.27 ? 709 VAL A N   1 
ATOM 5505 C CA  . VAL A 1 709 ? 81.186  108.660 88.357  1.00 181.27 ? 709 VAL A CA  1 
ATOM 5506 C C   . VAL A 1 709 ? 80.701  109.724 89.336  1.00 181.27 ? 709 VAL A C   1 
ATOM 5507 O O   . VAL A 1 709 ? 81.214  110.850 89.314  1.00 181.27 ? 709 VAL A O   1 
ATOM 5508 C CB  . VAL A 1 709 ? 80.553  108.865 86.969  1.00 181.27 ? 709 VAL A CB  1 
ATOM 5509 C CG1 . VAL A 1 709 ? 79.042  108.996 87.071  1.00 181.27 ? 709 VAL A CG1 1 
ATOM 5510 C CG2 . VAL A 1 709 ? 81.164  110.073 86.271  1.00 181.27 ? 709 VAL A CG2 1 
ATOM 5511 N N   . LYS A 1 710 ? 79.730  109.401 90.194  1.00 187.20 ? 710 LYS A N   1 
ATOM 5512 C CA  . LYS A 1 710 ? 79.164  110.414 91.082  1.00 187.20 ? 710 LYS A CA  1 
ATOM 5513 C C   . LYS A 1 710 ? 80.192  111.071 91.998  1.00 187.20 ? 710 LYS A C   1 
ATOM 5514 O O   . LYS A 1 710 ? 80.192  112.312 92.077  1.00 187.20 ? 710 LYS A O   1 
ATOM 5515 C CB  . LYS A 1 710 ? 78.013  109.809 91.899  1.00 187.20 ? 710 LYS A CB  1 
ATOM 5516 C CG  . LYS A 1 710 ? 77.347  110.794 92.852  1.00 187.20 ? 710 LYS A CG  1 
ATOM 5517 C CD  . LYS A 1 710 ? 76.226  110.136 93.639  1.00 187.20 ? 710 LYS A CD  1 
ATOM 5518 C CE  . LYS A 1 710 ? 75.604  111.109 94.625  1.00 187.20 ? 710 LYS A CE  1 
ATOM 5519 N NZ  . LYS A 1 710 ? 74.516  110.478 95.419  1.00 187.20 ? 710 LYS A NZ  1 
ATOM 5520 N N   . PRO A 1 711 ? 81.065  110.345 92.712  1.00 187.75 ? 711 PRO A N   1 
ATOM 5521 C CA  . PRO A 1 711 ? 82.079  111.044 93.520  1.00 187.75 ? 711 PRO A CA  1 
ATOM 5522 C C   . PRO A 1 711 ? 82.993  111.941 92.703  1.00 187.75 ? 711 PRO A C   1 
ATOM 5523 O O   . PRO A 1 711 ? 83.371  113.017 93.183  1.00 187.75 ? 711 PRO A O   1 
ATOM 5524 C CB  . PRO A 1 711 ? 82.856  109.898 94.186  1.00 187.75 ? 711 PRO A CB  1 
ATOM 5525 C CG  . PRO A 1 711 ? 82.555  108.692 93.361  1.00 187.75 ? 711 PRO A CG  1 
ATOM 5526 C CD  . PRO A 1 711 ? 81.151  108.885 92.891  1.00 187.75 ? 711 PRO A CD  1 
ATOM 5527 N N   . GLN A 1 712 ? 83.361  111.537 91.485  1.00 184.21 ? 712 GLN A N   1 
ATOM 5528 C CA  . GLN A 1 712 ? 84.190  112.390 90.641  1.00 184.21 ? 712 GLN A CA  1 
ATOM 5529 C C   . GLN A 1 712 ? 83.456  113.650 90.201  1.00 184.21 ? 712 GLN A C   1 
ATOM 5530 O O   . GLN A 1 712 ? 84.075  114.715 90.097  1.00 184.21 ? 712 GLN A O   1 
ATOM 5531 C CB  . GLN A 1 712 ? 84.683  111.611 89.420  1.00 184.21 ? 712 GLN A CB  1 
ATOM 5532 C CG  . GLN A 1 712 ? 85.707  110.523 89.729  1.00 184.21 ? 712 GLN A CG  1 
ATOM 5533 C CD  . GLN A 1 712 ? 87.114  111.063 89.942  1.00 184.21 ? 712 GLN A CD  1 
ATOM 5534 O OE1 . GLN A 1 712 ? 87.303  112.210 90.349  1.00 184.21 ? 712 GLN A OE1 1 
ATOM 5535 N NE2 . GLN A 1 712 ? 88.111  110.232 89.660  1.00 184.21 ? 712 GLN A NE2 1 
ATOM 5536 N N   . ILE A 1 713 ? 82.154  113.550 89.919  1.00 180.36 ? 713 ILE A N   1 
ATOM 5537 C CA  . ILE A 1 713 ? 81.376  114.734 89.564  1.00 180.36 ? 713 ILE A CA  1 
ATOM 5538 C C   . ILE A 1 713 ? 81.347  115.718 90.726  1.00 180.36 ? 713 ILE A C   1 
ATOM 5539 O O   . ILE A 1 713 ? 81.516  116.929 90.540  1.00 180.36 ? 713 ILE A O   1 
ATOM 5540 C CB  . ILE A 1 713 ? 79.957  114.329 89.124  1.00 180.36 ? 713 ILE A CB  1 
ATOM 5541 C CG1 . ILE A 1 713 ? 80.022  113.441 87.881  1.00 180.36 ? 713 ILE A CG1 1 
ATOM 5542 C CG2 . ILE A 1 713 ? 79.111  115.559 88.846  1.00 180.36 ? 713 ILE A CG2 1 
ATOM 5543 C CD1 . ILE A 1 713 ? 78.683  112.888 87.451  1.00 180.36 ? 713 ILE A CD1 1 
ATOM 5544 N N   . LEU A 1 714 ? 81.132  115.215 91.944  1.00 187.59 ? 714 LEU A N   1 
ATOM 5545 C CA  . LEU A 1 714 ? 81.180  116.078 93.119  1.00 187.59 ? 714 LEU A CA  1 
ATOM 5546 C C   . LEU A 1 714 ? 82.590  116.592 93.380  1.00 187.59 ? 714 LEU A C   1 
ATOM 5547 O O   . LEU A 1 714 ? 82.762  117.600 94.076  1.00 187.59 ? 714 LEU A O   1 
ATOM 5548 C CB  . LEU A 1 714 ? 80.658  115.328 94.345  1.00 187.59 ? 714 LEU A CB  1 
ATOM 5549 C CG  . LEU A 1 714 ? 79.228  114.785 94.289  1.00 187.59 ? 714 LEU A CG  1 
ATOM 5550 C CD1 . LEU A 1 714 ? 78.908  113.981 95.540  1.00 187.59 ? 714 LEU A CD1 1 
ATOM 5551 C CD2 . LEU A 1 714 ? 78.228  115.916 94.110  1.00 187.59 ? 714 LEU A CD2 1 
ATOM 5552 N N   . SER A 1 715 ? 83.605  115.912 92.843  1.00 189.08 ? 715 SER A N   1 
ATOM 5553 C CA  . SER A 1 715 ? 84.986  116.300 93.114  1.00 189.08 ? 715 SER A CA  1 
ATOM 5554 C C   . SER A 1 715 ? 85.354  117.600 92.409  1.00 189.08 ? 715 SER A C   1 
ATOM 5555 O O   . SER A 1 715 ? 86.195  118.362 92.902  1.00 189.08 ? 715 SER A O   1 
ATOM 5556 C CB  . SER A 1 715 ? 85.937  115.177 92.703  1.00 189.08 ? 715 SER A CB  1 
ATOM 5557 O OG  . SER A 1 715 ? 85.712  114.010 93.476  1.00 189.08 ? 715 SER A OG  1 
ATOM 5558 N N   . VAL A 1 716 ? 84.742  117.871 91.255  1.00 180.98 ? 716 VAL A N   1 
ATOM 5559 C CA  . VAL A 1 716 ? 85.134  119.035 90.466  1.00 180.98 ? 716 VAL A CA  1 
ATOM 5560 C C   . VAL A 1 716 ? 84.479  120.320 90.960  1.00 180.98 ? 716 VAL A C   1 
ATOM 5561 O O   . VAL A 1 716 ? 84.904  121.414 90.566  1.00 180.98 ? 716 VAL A O   1 
ATOM 5562 C CB  . VAL A 1 716 ? 84.810  118.797 88.981  1.00 180.98 ? 716 VAL A CB  1 
ATOM 5563 C CG1 . VAL A 1 716 ? 83.324  118.951 88.731  1.00 180.98 ? 716 VAL A CG1 1 
ATOM 5564 C CG2 . VAL A 1 716 ? 85.625  119.730 88.085  1.00 180.98 ? 716 VAL A CG2 1 
ATOM 5565 N N   . PHE A 1 717 ? 83.464  120.225 91.821  1.00 191.29 ? 717 PHE A N   1 
ATOM 5566 C CA  . PHE A 1 717 ? 82.788  121.427 92.298  1.00 191.29 ? 717 PHE A CA  1 
ATOM 5567 C C   . PHE A 1 717 ? 83.714  122.294 93.142  1.00 191.29 ? 717 PHE A C   1 
ATOM 5568 O O   . PHE A 1 717 ? 83.687  123.526 93.038  1.00 191.29 ? 717 PHE A O   1 
ATOM 5569 C CB  . PHE A 1 717 ? 81.540  121.047 93.094  1.00 191.29 ? 717 PHE A CB  1 
ATOM 5570 C CG  . PHE A 1 717 ? 80.434  120.480 92.253  1.00 191.29 ? 717 PHE A CG  1 
ATOM 5571 C CD1 . PHE A 1 717 ? 80.293  120.850 90.927  1.00 191.29 ? 717 PHE A CD1 1 
ATOM 5572 C CD2 . PHE A 1 717 ? 79.535  119.575 92.790  1.00 191.29 ? 717 PHE A CD2 1 
ATOM 5573 C CE1 . PHE A 1 717 ? 79.275  120.329 90.153  1.00 191.29 ? 717 PHE A CE1 1 
ATOM 5574 C CE2 . PHE A 1 717 ? 78.517  119.051 92.021  1.00 191.29 ? 717 PHE A CE2 1 
ATOM 5575 C CZ  . PHE A 1 717 ? 78.387  119.428 90.701  1.00 191.29 ? 717 PHE A CZ  1 
ATOM 5576 N N   . GLY A 1 718 ? 84.527  121.673 93.998  1.00 193.59 ? 718 GLY A N   1 
ATOM 5577 C CA  . GLY A 1 718 ? 85.376  122.448 94.888  1.00 193.59 ? 718 GLY A CA  1 
ATOM 5578 C C   . GLY A 1 718 ? 86.459  123.232 94.169  1.00 193.59 ? 718 GLY A C   1 
ATOM 5579 O O   . GLY A 1 718 ? 86.674  124.413 94.454  1.00 193.59 ? 718 GLY A O   1 
ATOM 5580 N N   . ASP A 1 719 ? 87.151  122.594 93.223  1.00 185.42 ? 719 ASP A N   1 
ATOM 5581 C CA  . ASP A 1 719 ? 88.329  123.209 92.622  1.00 185.42 ? 719 ASP A CA  1 
ATOM 5582 C C   . ASP A 1 719 ? 88.004  124.394 91.721  1.00 185.42 ? 719 ASP A C   1 
ATOM 5583 O O   . ASP A 1 719 ? 88.813  125.325 91.637  1.00 185.42 ? 719 ASP A O   1 
ATOM 5584 C CB  . ASP A 1 719 ? 89.130  122.167 91.838  1.00 185.42 ? 719 ASP A CB  1 
ATOM 5585 C CG  . ASP A 1 719 ? 88.261  121.329 90.926  1.00 185.42 ? 719 ASP A CG  1 
ATOM 5586 O OD1 . ASP A 1 719 ? 87.713  121.880 89.949  1.00 185.42 ? 719 ASP A OD1 1 
ATOM 5587 O OD2 . ASP A 1 719 ? 88.132  120.115 91.186  1.00 185.42 ? 719 ASP A OD2 1 
ATOM 5588 N N   . ILE A 1 720 ? 86.859  124.379 91.033  1.00 183.84 ? 720 ILE A N   1 
ATOM 5589 C CA  . ILE A 1 720 ? 86.530  125.482 90.133  1.00 183.84 ? 720 ILE A CA  1 
ATOM 5590 C C   . ILE A 1 720 ? 86.348  126.786 90.902  1.00 183.84 ? 720 ILE A C   1 
ATOM 5591 O O   . ILE A 1 720 ? 86.576  127.872 90.356  1.00 183.84 ? 720 ILE A O   1 
ATOM 5592 C CB  . ILE A 1 720 ? 85.284  125.143 89.294  1.00 183.84 ? 720 ILE A CB  1 
ATOM 5593 C CG1 . ILE A 1 720 ? 84.076  124.899 90.197  1.00 183.84 ? 720 ILE A CG1 1 
ATOM 5594 C CG2 . ILE A 1 720 ? 85.544  123.926 88.421  1.00 183.84 ? 720 ILE A CG2 1 
ATOM 5595 C CD1 . ILE A 1 720 ? 82.804  124.604 89.437  1.00 183.84 ? 720 ILE A CD1 1 
ATOM 5596 N N   . ALA A 1 721 ? 85.932  126.711 92.169  1.00 200.27 ? 721 ALA A N   1 
ATOM 5597 C CA  . ALA A 1 721 ? 85.791  127.924 92.967  1.00 200.27 ? 721 ALA A CA  1 
ATOM 5598 C C   . ALA A 1 721 ? 87.150  128.477 93.376  1.00 200.27 ? 721 ALA A C   1 
ATOM 5599 O O   . ALA A 1 721 ? 87.303  129.690 93.565  1.00 200.27 ? 721 ALA A O   1 
ATOM 5600 C CB  . ALA A 1 721 ? 84.928  127.650 94.198  1.00 200.27 ? 721 ALA A CB  1 
ATOM 5601 N N   . LEU A 1 722 ? 88.147  127.601 93.527  1.00 191.10 ? 722 LEU A N   1 
ATOM 5602 C CA  . LEU A 1 722 ? 89.481  128.049 93.915  1.00 191.10 ? 722 LEU A CA  1 
ATOM 5603 C C   . LEU A 1 722 ? 90.107  128.949 92.858  1.00 191.10 ? 722 LEU A C   1 
ATOM 5604 O O   . LEU A 1 722 ? 90.909  129.828 93.192  1.00 191.10 ? 722 LEU A O   1 
ATOM 5605 C CB  . LEU A 1 722 ? 90.381  126.842 94.179  1.00 191.10 ? 722 LEU A CB  1 
ATOM 5606 C CG  . LEU A 1 722 ? 91.023  126.740 95.563  1.00 191.10 ? 722 LEU A CG  1 
ATOM 5607 C CD1 . LEU A 1 722 ? 91.866  125.477 95.673  1.00 191.10 ? 722 LEU A CD1 1 
ATOM 5608 C CD2 . LEU A 1 722 ? 91.858  127.974 95.863  1.00 191.10 ? 722 LEU A CD2 1 
ATOM 5609 N N   . ALA A 1 723 ? 89.755  128.752 91.586  1.00 191.52 ? 723 ALA A N   1 
ATOM 5610 C CA  . ALA A 1 723 ? 90.351  129.552 90.521  1.00 191.52 ? 723 ALA A CA  1 
ATOM 5611 C C   . ALA A 1 723 ? 89.653  130.900 90.386  1.00 191.52 ? 723 ALA A C   1 
ATOM 5612 O O   . ALA A 1 723 ? 90.302  131.952 90.421  1.00 191.52 ? 723 ALA A O   1 
ATOM 5613 C CB  . ALA A 1 723 ? 90.305  128.786 89.199  1.00 191.52 ? 723 ALA A CB  1 
ATOM 5614 N N   . ILE A 1 724 ? 88.328  130.889 90.215  1.00 200.15 ? 724 ILE A N   1 
ATOM 5615 C CA  . ILE A 1 724 ? 87.582  132.135 90.042  1.00 200.15 ? 724 ILE A CA  1 
ATOM 5616 C C   . ILE A 1 724 ? 87.586  133.008 91.287  1.00 200.15 ? 724 ILE A C   1 
ATOM 5617 O O   . ILE A 1 724 ? 87.624  134.239 91.164  1.00 200.15 ? 724 ILE A O   1 
ATOM 5618 C CB  . ILE A 1 724 ? 86.130  131.845 89.618  1.00 200.15 ? 724 ILE A CB  1 
ATOM 5619 C CG1 . ILE A 1 724 ? 85.445  130.925 90.629  1.00 200.15 ? 724 ILE A CG1 1 
ATOM 5620 C CG2 . ILE A 1 724 ? 86.097  131.212 88.237  1.00 200.15 ? 724 ILE A CG2 1 
ATOM 5621 C CD1 . ILE A 1 724 ? 84.024  130.562 90.258  1.00 200.15 ? 724 ILE A CD1 1 
ATOM 5622 N N   . GLY A 1 725 ? 87.559  132.416 92.475  1.00 208.49 ? 725 GLY A N   1 
ATOM 5623 C CA  . GLY A 1 725 ? 87.565  133.211 93.696  1.00 208.49 ? 725 GLY A CA  1 
ATOM 5624 C C   . GLY A 1 725 ? 86.178  133.333 94.287  1.00 208.49 ? 725 GLY A C   1 
ATOM 5625 O O   . GLY A 1 725 ? 85.561  132.334 94.670  1.00 208.49 ? 725 GLY A O   1 
ATOM 5626 N N   . GLY A 1 726 ? 85.675  134.564 94.357  1.00 211.19 ? 726 GLY A N   1 
ATOM 5627 C CA  . GLY A 1 726 ? 84.391  134.827 94.979  1.00 211.19 ? 726 GLY A CA  1 
ATOM 5628 C C   . GLY A 1 726 ? 83.298  135.154 93.984  1.00 211.19 ? 726 GLY A C   1 
ATOM 5629 O O   . GLY A 1 726 ? 82.454  136.021 94.235  1.00 211.19 ? 726 GLY A O   1 
ATOM 5630 N N   . GLU A 1 727 ? 83.302  134.464 92.845  1.00 207.76 ? 727 GLU A N   1 
ATOM 5631 C CA  . GLU A 1 727 ? 82.305  134.658 91.802  1.00 207.76 ? 727 GLU A CA  1 
ATOM 5632 C C   . GLU A 1 727 ? 81.369  133.465 91.667  1.00 207.76 ? 727 GLU A C   1 
ATOM 5633 O O   . GLU A 1 727 ? 80.546  133.434 90.747  1.00 207.76 ? 727 GLU A O   1 
ATOM 5634 C CB  . GLU A 1 727 ? 82.992  134.936 90.462  1.00 207.76 ? 727 GLU A CB  1 
ATOM 5635 C CG  . GLU A 1 727 ? 84.388  135.536 90.586  1.00 207.76 ? 727 GLU A CG  1 
ATOM 5636 C CD  . GLU A 1 727 ? 84.386  136.942 91.159  1.00 207.76 ? 727 GLU A CD  1 
ATOM 5637 O OE1 . GLU A 1 727 ? 83.353  137.633 91.048  1.00 207.76 ? 727 GLU A OE1 1 
ATOM 5638 O OE2 . GLU A 1 727 ? 85.423  137.357 91.716  1.00 207.76 ? 727 GLU A OE2 1 
ATOM 5639 N N   . PHE A 1 728 ? 81.481  132.483 92.559  1.00 206.45 ? 728 PHE A N   1 
ATOM 5640 C CA  . PHE A 1 728 ? 80.695  131.258 92.499  1.00 206.45 ? 728 PHE A CA  1 
ATOM 5641 C C   . PHE A 1 728 ? 79.405  131.333 93.310  1.00 206.45 ? 728 PHE A C   1 
ATOM 5642 O O   . PHE A 1 728 ? 78.714  130.318 93.443  1.00 206.45 ? 728 PHE A O   1 
ATOM 5643 C CB  . PHE A 1 728 ? 81.535  130.073 92.981  1.00 206.45 ? 728 PHE A CB  1 
ATOM 5644 C CG  . PHE A 1 728 ? 81.109  128.757 92.401  1.00 206.45 ? 728 PHE A CG  1 
ATOM 5645 C CD1 . PHE A 1 728 ? 80.407  128.707 91.209  1.00 206.45 ? 728 PHE A CD1 1 
ATOM 5646 C CD2 . PHE A 1 728 ? 81.398  127.571 93.054  1.00 206.45 ? 728 PHE A CD2 1 
ATOM 5647 C CE1 . PHE A 1 728 ? 80.010  127.500 90.672  1.00 206.45 ? 728 PHE A CE1 1 
ATOM 5648 C CE2 . PHE A 1 728 ? 81.002  126.359 92.522  1.00 206.45 ? 728 PHE A CE2 1 
ATOM 5649 C CZ  . PHE A 1 728 ? 80.306  126.324 91.329  1.00 206.45 ? 728 PHE A CZ  1 
ATOM 5650 N N   . LYS A 1 729 ? 79.079  132.499 93.873  1.00 206.53 ? 729 LYS A N   1 
ATOM 5651 C CA  . LYS A 1 729 ? 77.896  132.625 94.719  1.00 206.53 ? 729 LYS A CA  1 
ATOM 5652 C C   . LYS A 1 729 ? 76.595  132.357 93.970  1.00 206.53 ? 729 LYS A C   1 
ATOM 5653 O O   . LYS A 1 729 ? 75.599  131.988 94.601  1.00 206.53 ? 729 LYS A O   1 
ATOM 5654 C CB  . LYS A 1 729 ? 77.854  134.018 95.349  1.00 206.53 ? 729 LYS A CB  1 
ATOM 5655 C CG  . LYS A 1 729 ? 78.987  134.284 96.326  1.00 206.53 ? 729 LYS A CG  1 
ATOM 5656 C CD  . LYS A 1 729 ? 79.091  135.759 96.671  1.00 206.53 ? 729 LYS A CD  1 
ATOM 5657 C CE  . LYS A 1 729 ? 79.435  136.584 95.441  1.00 206.53 ? 729 LYS A CE  1 
ATOM 5658 N NZ  . LYS A 1 729 ? 79.666  138.017 95.772  1.00 206.53 ? 729 LYS A NZ  1 
ATOM 5659 N N   . LYS A 1 730 ? 76.575  132.533 92.647  1.00 199.08 ? 730 LYS A N   1 
ATOM 5660 C CA  . LYS A 1 730 ? 75.353  132.308 91.882  1.00 199.08 ? 730 LYS A CA  1 
ATOM 5661 C C   . LYS A 1 730 ? 74.978  130.834 91.777  1.00 199.08 ? 730 LYS A C   1 
ATOM 5662 O O   . LYS A 1 730 ? 73.840  130.525 91.409  1.00 199.08 ? 730 LYS A O   1 
ATOM 5663 C CB  . LYS A 1 730 ? 75.488  132.915 90.483  1.00 199.08 ? 730 LYS A CB  1 
ATOM 5664 C CG  . LYS A 1 730 ? 76.810  132.619 89.793  1.00 199.08 ? 730 LYS A CG  1 
ATOM 5665 C CD  . LYS A 1 730 ? 76.905  133.337 88.457  1.00 199.08 ? 730 LYS A CD  1 
ATOM 5666 C CE  . LYS A 1 730 ? 78.241  133.077 87.780  1.00 199.08 ? 730 LYS A CE  1 
ATOM 5667 N NZ  . LYS A 1 730 ? 79.389  133.520 88.619  1.00 199.08 ? 730 LYS A NZ  1 
ATOM 5668 N N   . TYR A 1 731 ? 75.899  129.924 92.090  1.00 200.82 ? 731 TYR A N   1 
ATOM 5669 C CA  . TYR A 1 731 ? 75.615  128.495 92.108  1.00 200.82 ? 731 TYR A CA  1 
ATOM 5670 C C   . TYR A 1 731 ? 75.798  127.877 93.487  1.00 200.82 ? 731 TYR A C   1 
ATOM 5671 O O   . TYR A 1 731 ? 75.630  126.661 93.634  1.00 200.82 ? 731 TYR A O   1 
ATOM 5672 C CB  . TYR A 1 731 ? 76.502  127.761 91.095  1.00 200.82 ? 731 TYR A CB  1 
ATOM 5673 C CG  . TYR A 1 731 ? 76.380  128.268 89.675  1.00 200.82 ? 731 TYR A CG  1 
ATOM 5674 C CD1 . TYR A 1 731 ? 75.347  127.843 88.850  1.00 200.82 ? 731 TYR A CD1 1 
ATOM 5675 C CD2 . TYR A 1 731 ? 77.304  129.166 89.158  1.00 200.82 ? 731 TYR A CD2 1 
ATOM 5676 C CE1 . TYR A 1 731 ? 75.235  128.304 87.551  1.00 200.82 ? 731 TYR A CE1 1 
ATOM 5677 C CE2 . TYR A 1 731 ? 77.201  129.632 87.861  1.00 200.82 ? 731 TYR A CE2 1 
ATOM 5678 C CZ  . TYR A 1 731 ? 76.165  129.198 87.061  1.00 200.82 ? 731 TYR A CZ  1 
ATOM 5679 O OH  . TYR A 1 731 ? 76.058  129.660 85.769  1.00 200.82 ? 731 TYR A OH  1 
ATOM 5680 N N   . LEU A 1 732 ? 76.147  128.678 94.498  1.00 200.46 ? 732 LEU A N   1 
ATOM 5681 C CA  . LEU A 1 732 ? 76.447  128.132 95.819  1.00 200.46 ? 732 LEU A CA  1 
ATOM 5682 C C   . LEU A 1 732 ? 75.218  127.498 96.462  1.00 200.46 ? 732 LEU A C   1 
ATOM 5683 O O   . LEU A 1 732 ? 75.325  126.466 97.134  1.00 200.46 ? 732 LEU A O   1 
ATOM 5684 C CB  . LEU A 1 732 ? 77.016  129.230 96.718  1.00 200.46 ? 732 LEU A CB  1 
ATOM 5685 C CG  . LEU A 1 732 ? 77.481  128.811 98.113  1.00 200.46 ? 732 LEU A CG  1 
ATOM 5686 C CD1 . LEU A 1 732 ? 78.837  129.423 98.415  1.00 200.46 ? 732 LEU A CD1 1 
ATOM 5687 C CD2 . LEU A 1 732 ? 76.466  129.217 99.168  1.00 200.46 ? 732 LEU A CD2 1 
ATOM 5688 N N   . GLU A 1 733 ? 74.045  128.107 96.283  1.00 216.05 ? 733 GLU A N   1 
ATOM 5689 C CA  . GLU A 1 733 ? 72.843  127.586 96.928  1.00 216.05 ? 733 GLU A CA  1 
ATOM 5690 C C   . GLU A 1 733 ? 72.451  126.224 96.365  1.00 216.05 ? 733 GLU A C   1 
ATOM 5691 O O   . GLU A 1 733 ? 71.989  125.349 97.107  1.00 216.05 ? 733 GLU A O   1 
ATOM 5692 C CB  . GLU A 1 733 ? 71.693  128.582 96.779  1.00 216.05 ? 733 GLU A CB  1 
ATOM 5693 C CG  . GLU A 1 733 ? 72.010  129.976 97.299  1.00 216.05 ? 733 GLU A CG  1 
ATOM 5694 C CD  . GLU A 1 733 ? 72.277  130.001 98.793  1.00 216.05 ? 733 GLU A CD  1 
ATOM 5695 O OE1 . GLU A 1 733 ? 71.706  129.159 99.517  1.00 216.05 ? 733 GLU A OE1 1 
ATOM 5696 O OE2 . GLU A 1 733 ? 73.061  130.864 99.243  1.00 216.05 ? 733 GLU A OE2 1 
ATOM 5697 N N   . VAL A 1 734 ? 72.619  126.029 95.056  1.00 210.50 ? 734 VAL A N   1 
ATOM 5698 C CA  . VAL A 1 734 ? 72.175  124.791 94.422  1.00 210.50 ? 734 VAL A CA  1 
ATOM 5699 C C   . VAL A 1 734 ? 73.039  123.612 94.858  1.00 210.50 ? 734 VAL A C   1 
ATOM 5700 O O   . VAL A 1 734 ? 72.523  122.531 95.167  1.00 210.50 ? 734 VAL A O   1 
ATOM 5701 C CB  . VAL A 1 734 ? 72.167  124.952 92.891  1.00 210.50 ? 734 VAL A CB  1 
ATOM 5702 C CG1 . VAL A 1 734 ? 71.597  123.708 92.230  1.00 210.50 ? 734 VAL A CG1 1 
ATOM 5703 C CG2 . VAL A 1 734 ? 71.372  126.187 92.493  1.00 210.50 ? 734 VAL A CG2 1 
ATOM 5704 N N   . VAL A 1 735 ? 74.363  123.793 94.884  1.00 217.88 ? 735 VAL A N   1 
ATOM 5705 C CA  . VAL A 1 735 ? 75.252  122.674 95.189  1.00 217.88 ? 735 VAL A CA  1 
ATOM 5706 C C   . VAL A 1 735 ? 75.069  122.198 96.624  1.00 217.88 ? 735 VAL A C   1 
ATOM 5707 O O   . VAL A 1 735 ? 75.097  120.989 96.889  1.00 217.88 ? 735 VAL A O   1 
ATOM 5708 C CB  . VAL A 1 735 ? 76.720  123.046 94.904  1.00 217.88 ? 735 VAL A CB  1 
ATOM 5709 C CG1 . VAL A 1 735 ? 76.971  123.085 93.410  1.00 217.88 ? 735 VAL A CG1 1 
ATOM 5710 C CG2 . VAL A 1 735 ? 77.074  124.380 95.538  1.00 217.88 ? 735 VAL A CG2 1 
ATOM 5711 N N   . LEU A 1 736 ? 74.881  123.122 97.570  1.00 216.74 ? 736 LEU A N   1 
ATOM 5712 C CA  . LEU A 1 736 ? 74.738  122.732 98.969  1.00 216.74 ? 736 LEU A CA  1 
ATOM 5713 C C   . LEU A 1 736 ? 73.524  121.834 99.174  1.00 216.74 ? 736 LEU A C   1 
ATOM 5714 O O   . LEU A 1 736 ? 73.572  120.892 99.973  1.00 216.74 ? 736 LEU A O   1 
ATOM 5715 C CB  . LEU A 1 736 ? 74.648  123.974 99.854  1.00 216.74 ? 736 LEU A CB  1 
ATOM 5716 C CG  . LEU A 1 736 ? 75.935  124.795 99.949  1.00 216.74 ? 736 LEU A CG  1 
ATOM 5717 C CD1 . LEU A 1 736 ? 75.741  125.994 100.858 1.00 216.74 ? 736 LEU A CD1 1 
ATOM 5718 C CD2 . LEU A 1 736 ? 77.086  123.930 100.439 1.00 216.74 ? 736 LEU A CD2 1 
ATOM 5719 N N   . ASN A 1 737 ? 72.427  122.111 98.465  1.00 232.30 ? 737 ASN A N   1 
ATOM 5720 C CA  . ASN A 1 737 ? 71.270  121.225 98.527  1.00 232.30 ? 737 ASN A CA  1 
ATOM 5721 C C   . ASN A 1 737 ? 71.608  119.839 97.990  1.00 232.30 ? 737 ASN A C   1 
ATOM 5722 O O   . ASN A 1 737 ? 71.219  118.826 98.583  1.00 232.30 ? 737 ASN A O   1 
ATOM 5723 C CB  . ASN A 1 737 ? 70.100  121.834 97.756  1.00 232.30 ? 737 ASN A CB  1 
ATOM 5724 C CG  . ASN A 1 737 ? 69.625  123.142 98.357  1.00 232.30 ? 737 ASN A CG  1 
ATOM 5725 O OD1 . ASN A 1 737 ? 69.732  123.360 99.564  1.00 232.30 ? 737 ASN A OD1 1 
ATOM 5726 N ND2 . ASN A 1 737 ? 69.093  124.020 97.515  1.00 232.30 ? 737 ASN A ND2 1 
ATOM 5727 N N   . THR A 1 738 ? 72.324  119.774 96.864  1.00 228.37 ? 738 THR A N   1 
ATOM 5728 C CA  . THR A 1 738 ? 72.777  118.486 96.347  1.00 228.37 ? 738 THR A CA  1 
ATOM 5729 C C   . THR A 1 738 ? 73.787  117.841 97.288  1.00 228.37 ? 738 THR A C   1 
ATOM 5730 O O   . THR A 1 738 ? 73.752  116.625 97.508  1.00 228.37 ? 738 THR A O   1 
ATOM 5731 C CB  . THR A 1 738 ? 73.378  118.656 94.952  1.00 228.37 ? 738 THR A CB  1 
ATOM 5732 O OG1 . THR A 1 738 ? 74.561  119.460 95.033  1.00 228.37 ? 738 THR A OG1 1 
ATOM 5733 C CG2 . THR A 1 738 ? 72.377  119.326 94.022  1.00 228.37 ? 738 THR A CG2 1 
ATOM 5734 N N   . LEU A 1 739 ? 74.701  118.641 97.845  1.00 231.10 ? 739 LEU A N   1 
ATOM 5735 C CA  . LEU A 1 739 ? 75.629  118.126 98.845  1.00 231.10 ? 739 LEU A CA  1 
ATOM 5736 C C   . LEU A 1 739 ? 74.894  117.631 100.083 1.00 231.10 ? 739 LEU A C   1 
ATOM 5737 O O   . LEU A 1 739 ? 75.288  116.618 100.673 1.00 231.10 ? 739 LEU A O   1 
ATOM 5738 C CB  . LEU A 1 739 ? 76.647  119.205 99.218  1.00 231.10 ? 739 LEU A CB  1 
ATOM 5739 C CG  . LEU A 1 739 ? 77.664  119.556 98.129  1.00 231.10 ? 739 LEU A CG  1 
ATOM 5740 C CD1 . LEU A 1 739 ? 78.221  120.955 98.334  1.00 231.10 ? 739 LEU A CD1 1 
ATOM 5741 C CD2 . LEU A 1 739 ? 78.789  118.532 98.098  1.00 231.10 ? 739 LEU A CD2 1 
ATOM 5742 N N   . GLN A 1 740 ? 73.840  118.338 100.498 1.00 242.58 ? 740 GLN A N   1 
ATOM 5743 C CA  . GLN A 1 740 ? 72.995  117.852 101.584 1.00 242.58 ? 740 GLN A CA  1 
ATOM 5744 C C   . GLN A 1 740 ? 72.369  116.508 101.230 1.00 242.58 ? 740 GLN A C   1 
ATOM 5745 O O   . GLN A 1 740 ? 72.430  115.555 102.015 1.00 242.58 ? 740 GLN A O   1 
ATOM 5746 C CB  . GLN A 1 740 ? 71.912  118.884 101.900 1.00 242.58 ? 740 GLN A CB  1 
ATOM 5747 C CG  . GLN A 1 740 ? 70.813  118.386 102.826 1.00 242.58 ? 740 GLN A CG  1 
ATOM 5748 C CD  . GLN A 1 740 ? 71.203  118.450 104.288 1.00 242.58 ? 740 GLN A CD  1 
ATOM 5749 O OE1 . GLN A 1 740 ? 72.013  119.285 104.691 1.00 242.58 ? 740 GLN A OE1 1 
ATOM 5750 N NE2 . GLN A 1 740 ? 70.625  117.566 105.094 1.00 242.58 ? 740 GLN A NE2 1 
ATOM 5751 N N   . GLN A 1 741 ? 71.764  116.415 100.043 1.00 242.97 ? 741 GLN A N   1 
ATOM 5752 C CA  . GLN A 1 741 ? 71.098  115.181 99.636  1.00 242.97 ? 741 GLN A CA  1 
ATOM 5753 C C   . GLN A 1 741 ? 72.080  114.027 99.480  1.00 242.97 ? 741 GLN A C   1 
ATOM 5754 O O   . GLN A 1 741 ? 71.787  112.906 99.910  1.00 242.97 ? 741 GLN A O   1 
ATOM 5755 C CB  . GLN A 1 741 ? 70.331  115.409 98.332  1.00 242.97 ? 741 GLN A CB  1 
ATOM 5756 C CG  . GLN A 1 741 ? 69.530  114.206 97.849  1.00 242.97 ? 741 GLN A CG  1 
ATOM 5757 C CD  . GLN A 1 741 ? 70.321  113.304 96.920  1.00 242.97 ? 741 GLN A CD  1 
ATOM 5758 O OE1 . GLN A 1 741 ? 71.401  113.667 96.455  1.00 242.97 ? 741 GLN A OE1 1 
ATOM 5759 N NE2 . GLN A 1 741 ? 69.785  112.120 96.646  1.00 242.97 ? 741 GLN A NE2 1 
ATOM 5760 N N   . ALA A 1 742 ? 73.240  114.276 98.866  1.00 237.81 ? 742 ALA A N   1 
ATOM 5761 C CA  . ALA A 1 742 ? 74.212  113.208 98.659  1.00 237.81 ? 742 ALA A CA  1 
ATOM 5762 C C   . ALA A 1 742 ? 74.727  112.663 99.986  1.00 237.81 ? 742 ALA A C   1 
ATOM 5763 O O   . ALA A 1 742 ? 74.899  111.448 100.140 1.00 237.81 ? 742 ALA A O   1 
ATOM 5764 C CB  . ALA A 1 742 ? 75.370  113.711 97.799  1.00 237.81 ? 742 ALA A CB  1 
ATOM 5765 N N   . SER A 1 743 ? 74.981  113.546 100.951 1.00 241.79 ? 743 SER A N   1 
ATOM 5766 C CA  . SER A 1 743 ? 75.455  113.126 102.263 1.00 241.79 ? 743 SER A CA  1 
ATOM 5767 C C   . SER A 1 743 ? 74.401  112.372 103.063 1.00 241.79 ? 743 SER A C   1 
ATOM 5768 O O   . SER A 1 743 ? 74.759  111.619 103.975 1.00 241.79 ? 743 SER A O   1 
ATOM 5769 C CB  . SER A 1 743 ? 75.938  114.343 103.053 1.00 241.79 ? 743 SER A CB  1 
ATOM 5770 O OG  . SER A 1 743 ? 75.111  115.466 102.806 1.00 241.79 ? 743 SER A OG  1 
ATOM 5771 N N   . GLN A 1 744 ? 73.116  112.559 102.752 1.00 249.19 ? 744 GLN A N   1 
ATOM 5772 C CA  . GLN A 1 744 ? 72.064  111.832 103.454 1.00 249.19 ? 744 GLN A CA  1 
ATOM 5773 C C   . GLN A 1 744 ? 72.085  110.339 103.153 1.00 249.19 ? 744 GLN A C   1 
ATOM 5774 O O   . GLN A 1 744 ? 71.727  109.541 104.026 1.00 249.19 ? 744 GLN A O   1 
ATOM 5775 C CB  . GLN A 1 744 ? 70.690  112.405 103.098 1.00 249.19 ? 744 GLN A CB  1 
ATOM 5776 C CG  . GLN A 1 744 ? 70.408  113.786 103.669 1.00 249.19 ? 744 GLN A CG  1 
ATOM 5777 C CD  . GLN A 1 744 ? 70.175  113.770 105.167 1.00 249.19 ? 744 GLN A CD  1 
ATOM 5778 O OE1 . GLN A 1 744 ? 70.335  114.788 105.840 1.00 249.19 ? 744 GLN A OE1 1 
ATOM 5779 N NE2 . GLN A 1 744 ? 69.785  112.616 105.695 1.00 249.19 ? 744 GLN A NE2 1 
ATOM 5780 N N   . ALA A 1 745 ? 72.487  109.948 101.946 1.00 248.41 ? 745 ALA A N   1 
ATOM 5781 C CA  . ALA A 1 745 ? 72.448  108.551 101.540 1.00 248.41 ? 745 ALA A CA  1 
ATOM 5782 C C   . ALA A 1 745 ? 73.398  107.709 102.381 1.00 248.41 ? 745 ALA A C   1 
ATOM 5783 O O   . ALA A 1 745 ? 74.557  108.076 102.595 1.00 248.41 ? 745 ALA A O   1 
ATOM 5784 C CB  . ALA A 1 745 ? 72.805  108.416 100.060 1.00 248.41 ? 745 ALA A CB  1 
ATOM 5785 N N   . GLN A 1 746 ? 72.897  106.569 102.853 1.00 248.89 ? 746 GLN A N   1 
ATOM 5786 C CA  . GLN A 1 746 ? 73.687  105.620 103.621 1.00 248.89 ? 746 GLN A CA  1 
ATOM 5787 C C   . GLN A 1 746 ? 73.280  104.210 103.223 1.00 248.89 ? 746 GLN A C   1 
ATOM 5788 O O   . GLN A 1 746 ? 72.172  103.976 102.734 1.00 248.89 ? 746 GLN A O   1 
ATOM 5789 C CB  . GLN A 1 746 ? 73.507  105.814 105.135 1.00 248.89 ? 746 GLN A CB  1 
ATOM 5790 C CG  . GLN A 1 746 ? 74.082  107.111 105.683 1.00 248.89 ? 746 GLN A CG  1 
ATOM 5791 C CD  . GLN A 1 746 ? 75.597  107.150 105.630 1.00 248.89 ? 746 GLN A CD  1 
ATOM 5792 O OE1 . GLN A 1 746 ? 76.254  106.115 105.531 1.00 248.89 ? 746 GLN A OE1 1 
ATOM 5793 N NE2 . GLN A 1 746 ? 76.160  108.351 105.695 1.00 248.89 ? 746 GLN A NE2 1 
ATOM 5794 N N   . VAL A 1 747 ? 74.194  103.264 103.443 1.00 252.25 ? 747 VAL A N   1 
ATOM 5795 C CA  . VAL A 1 747 ? 73.955  101.862 103.125 1.00 252.25 ? 747 VAL A CA  1 
ATOM 5796 C C   . VAL A 1 747 ? 74.494  101.014 104.269 1.00 252.25 ? 747 VAL A C   1 
ATOM 5797 O O   . VAL A 1 747 ? 75.330  101.458 105.060 1.00 252.25 ? 747 VAL A O   1 
ATOM 5798 C CB  . VAL A 1 747 ? 74.601  101.452 101.777 1.00 252.25 ? 747 VAL A CB  1 
ATOM 5799 C CG1 . VAL A 1 747 ? 76.078  101.136 101.956 1.00 252.25 ? 747 VAL A CG1 1 
ATOM 5800 C CG2 . VAL A 1 747 ? 73.859  100.276 101.156 1.00 252.25 ? 747 VAL A CG2 1 
ATOM 5801 N N   . ASP A 1 748 ? 73.995  99.785  104.361 1.00 265.70 ? 748 ASP A N   1 
ATOM 5802 C CA  . ASP A 1 748 ? 74.421  98.868  105.406 1.00 265.70 ? 748 ASP A CA  1 
ATOM 5803 C C   . ASP A 1 748 ? 75.837  98.368  105.124 1.00 265.70 ? 748 ASP A C   1 
ATOM 5804 O O   . ASP A 1 748 ? 76.446  98.678  104.096 1.00 265.70 ? 748 ASP A O   1 
ATOM 5805 C CB  . ASP A 1 748 ? 73.443  97.701  105.515 1.00 265.70 ? 748 ASP A CB  1 
ATOM 5806 C CG  . ASP A 1 748 ? 73.385  96.871  104.246 1.00 265.70 ? 748 ASP A CG  1 
ATOM 5807 O OD1 . ASP A 1 748 ? 73.551  97.447  103.150 1.00 265.70 ? 748 ASP A OD1 1 
ATOM 5808 O OD2 . ASP A 1 748 ? 73.173  95.645  104.345 1.00 265.70 ? 748 ASP A OD2 1 
ATOM 5809 N N   . LYS A 1 749 ? 76.368  97.578  106.052 1.00 258.64 ? 749 LYS A N   1 
ATOM 5810 C CA  . LYS A 1 749 ? 77.683  96.962  105.900 1.00 258.64 ? 749 LYS A CA  1 
ATOM 5811 C C   . LYS A 1 749 ? 77.489  95.451  105.817 1.00 258.64 ? 749 LYS A C   1 
ATOM 5812 O O   . LYS A 1 749 ? 77.571  94.732  106.813 1.00 258.64 ? 749 LYS A O   1 
ATOM 5813 C CB  . LYS A 1 749 ? 78.612  97.354  107.056 1.00 258.64 ? 749 LYS A CB  1 
ATOM 5814 C CG  . LYS A 1 749 ? 78.893  98.844  107.152 1.00 258.64 ? 749 LYS A CG  1 
ATOM 5815 C CD  . LYS A 1 749 ? 79.871  99.149  108.275 1.00 258.64 ? 749 LYS A CD  1 
ATOM 5816 C CE  . LYS A 1 749 ? 80.077  100.648 108.431 1.00 258.64 ? 749 LYS A CE  1 
ATOM 5817 N NZ  . LYS A 1 749 ? 81.025  100.972 109.533 1.00 258.64 ? 749 LYS A NZ  1 
ATOM 5818 N N   . SER A 1 750 ? 77.227  94.974  104.611 1.00 264.80 ? 750 SER A N   1 
ATOM 5819 C CA  . SER A 1 750 ? 77.131  93.547  104.323 1.00 264.80 ? 750 SER A CA  1 
ATOM 5820 C C   . SER A 1 750 ? 77.987  93.129  103.139 1.00 264.80 ? 750 SER A C   1 
ATOM 5821 O O   . SER A 1 750 ? 78.555  92.034  103.155 1.00 264.80 ? 750 SER A O   1 
ATOM 5822 C CB  . SER A 1 750 ? 75.665  93.157  104.072 1.00 264.80 ? 750 SER A CB  1 
ATOM 5823 O OG  . SER A 1 750 ? 75.115  93.910  103.005 1.00 264.80 ? 750 SER A OG  1 
ATOM 5824 N N   . ASP A 1 751 ? 78.096  93.971  102.115 1.00 259.03 ? 751 ASP A N   1 
ATOM 5825 C CA  . ASP A 1 751 ? 78.888  93.687  100.927 1.00 259.03 ? 751 ASP A CA  1 
ATOM 5826 C C   . ASP A 1 751 ? 80.021  94.699  100.828 1.00 259.03 ? 751 ASP A C   1 
ATOM 5827 O O   . ASP A 1 751 ? 79.777  95.909  100.812 1.00 259.03 ? 751 ASP A O   1 
ATOM 5828 C CB  . ASP A 1 751 ? 78.018  93.728  99.669  1.00 259.03 ? 751 ASP A CB  1 
ATOM 5829 C CG  . ASP A 1 751 ? 78.805  93.441  98.406  1.00 259.03 ? 751 ASP A CG  1 
ATOM 5830 O OD1 . ASP A 1 751 ? 79.397  92.346  98.305  1.00 259.03 ? 751 ASP A OD1 1 
ATOM 5831 O OD2 . ASP A 1 751 ? 78.824  94.311  97.510  1.00 259.03 ? 751 ASP A OD2 1 
ATOM 5832 N N   . TYR A 1 752 ? 81.256  94.196  100.746 1.00 257.34 ? 752 TYR A N   1 
ATOM 5833 C CA  . TYR A 1 752 ? 82.432  95.058  100.806 1.00 257.34 ? 752 TYR A CA  1 
ATOM 5834 C C   . TYR A 1 752 ? 82.532  96.008  99.619  1.00 257.34 ? 752 TYR A C   1 
ATOM 5835 O O   . TYR A 1 752 ? 83.240  97.017  99.711  1.00 257.34 ? 752 TYR A O   1 
ATOM 5836 C CB  . TYR A 1 752 ? 83.697  94.203  100.896 1.00 257.34 ? 752 TYR A CB  1 
ATOM 5837 C CG  . TYR A 1 752 ? 83.617  93.116  101.943 1.00 257.34 ? 752 TYR A CG  1 
ATOM 5838 C CD1 . TYR A 1 752 ? 83.850  93.396  103.283 1.00 257.34 ? 752 TYR A CD1 1 
ATOM 5839 C CD2 . TYR A 1 752 ? 83.305  91.809  101.592 1.00 257.34 ? 752 TYR A CD2 1 
ATOM 5840 C CE1 . TYR A 1 752 ? 83.775  92.405  104.243 1.00 257.34 ? 752 TYR A CE1 1 
ATOM 5841 C CE2 . TYR A 1 752 ? 83.229  90.811  102.545 1.00 257.34 ? 752 TYR A CE2 1 
ATOM 5842 C CZ  . TYR A 1 752 ? 83.465  91.115  103.869 1.00 257.34 ? 752 TYR A CZ  1 
ATOM 5843 O OH  . TYR A 1 752 ? 83.390  90.125  104.822 1.00 257.34 ? 752 TYR A OH  1 
ATOM 5844 N N   . ASP A 1 753 ? 81.855  95.707  98.508  1.00 253.06 ? 753 ASP A N   1 
ATOM 5845 C CA  . ASP A 1 753 ? 81.912  96.591  97.349  1.00 253.06 ? 753 ASP A CA  1 
ATOM 5846 C C   . ASP A 1 753 ? 81.293  97.950  97.656  1.00 253.06 ? 753 ASP A C   1 
ATOM 5847 O O   . ASP A 1 753 ? 81.907  98.990  97.394  1.00 253.06 ? 753 ASP A O   1 
ATOM 5848 C CB  . ASP A 1 753 ? 81.214  95.939  96.157  1.00 253.06 ? 753 ASP A CB  1 
ATOM 5849 C CG  . ASP A 1 753 ? 81.769  94.566  95.839  1.00 253.06 ? 753 ASP A CG  1 
ATOM 5850 O OD1 . ASP A 1 753 ? 81.587  93.646  96.663  1.00 253.06 ? 753 ASP A OD1 1 
ATOM 5851 O OD2 . ASP A 1 753 ? 82.391  94.407  94.768  1.00 253.06 ? 753 ASP A OD2 1 
ATOM 5852 N N   . MET A 1 754 ? 80.078  97.961  98.210  1.00 247.91 ? 754 MET A N   1 
ATOM 5853 C CA  . MET A 1 754 ? 79.424  99.221  98.542  1.00 247.91 ? 754 MET A CA  1 
ATOM 5854 C C   . MET A 1 754 ? 79.931  99.815  99.851  1.00 247.91 ? 754 MET A C   1 
ATOM 5855 O O   . MET A 1 754 ? 79.768  101.020 100.071 1.00 247.91 ? 754 MET A O   1 
ATOM 5856 C CB  . MET A 1 754 ? 77.908  99.029  98.604  1.00 247.91 ? 754 MET A CB  1 
ATOM 5857 C CG  . MET A 1 754 ? 77.448  97.949  99.567  1.00 247.91 ? 754 MET A CG  1 
ATOM 5858 S SD  . MET A 1 754 ? 75.675  97.635  99.454  1.00 247.91 ? 754 MET A SD  1 
ATOM 5859 C CE  . MET A 1 754 ? 75.489  96.310  100.644 1.00 247.91 ? 754 MET A CE  1 
ATOM 5860 N N   . VAL A 1 755 ? 80.528  99.002  100.725 1.00 245.06 ? 755 VAL A N   1 
ATOM 5861 C CA  . VAL A 1 755 ? 81.094  99.529  101.964 1.00 245.06 ? 755 VAL A CA  1 
ATOM 5862 C C   . VAL A 1 755 ? 82.266  100.455 101.662 1.00 245.06 ? 755 VAL A C   1 
ATOM 5863 O O   . VAL A 1 755 ? 82.370  101.554 102.219 1.00 245.06 ? 755 VAL A O   1 
ATOM 5864 C CB  . VAL A 1 755 ? 81.509  98.379  102.899 1.00 245.06 ? 755 VAL A CB  1 
ATOM 5865 C CG1 . VAL A 1 755 ? 82.326  98.912  104.066 1.00 245.06 ? 755 VAL A CG1 1 
ATOM 5866 C CG2 . VAL A 1 755 ? 80.283  97.644  103.407 1.00 245.06 ? 755 VAL A CG2 1 
ATOM 5867 N N   . ASP A 1 756 ? 83.168  100.025 100.777 1.00 243.54 ? 756 ASP A N   1 
ATOM 5868 C CA  . ASP A 1 756 ? 84.287  100.881 100.400 1.00 243.54 ? 756 ASP A CA  1 
ATOM 5869 C C   . ASP A 1 756 ? 83.876  101.917 99.363  1.00 243.54 ? 756 ASP A C   1 
ATOM 5870 O O   . ASP A 1 756 ? 84.594  102.902 99.155  1.00 243.54 ? 756 ASP A O   1 
ATOM 5871 C CB  . ASP A 1 756 ? 85.447  100.031 99.880  1.00 243.54 ? 756 ASP A CB  1 
ATOM 5872 C CG  . ASP A 1 756 ? 86.026  99.121  100.948 1.00 243.54 ? 756 ASP A CG  1 
ATOM 5873 O OD1 . ASP A 1 756 ? 85.486  99.106  102.074 1.00 243.54 ? 756 ASP A OD1 1 
ATOM 5874 O OD2 . ASP A 1 756 ? 87.021  98.422  100.664 1.00 243.54 ? 756 ASP A OD2 1 
ATOM 5875 N N   . TYR A 1 757 ? 82.736  101.711 98.697  1.00 219.87 ? 757 TYR A N   1 
ATOM 5876 C CA  . TYR A 1 757 ? 82.244  102.702 97.746  1.00 219.87 ? 757 TYR A CA  1 
ATOM 5877 C C   . TYR A 1 757 ? 81.858  104.000 98.445  1.00 219.87 ? 757 TYR A C   1 
ATOM 5878 O O   . TYR A 1 757 ? 82.131  105.094 97.936  1.00 219.87 ? 757 TYR A O   1 
ATOM 5879 C CB  . TYR A 1 757 ? 81.056  102.140 96.966  1.00 219.87 ? 757 TYR A CB  1 
ATOM 5880 C CG  . TYR A 1 757 ? 80.314  103.178 96.155  1.00 219.87 ? 757 TYR A CG  1 
ATOM 5881 C CD1 . TYR A 1 757 ? 80.872  103.714 95.000  1.00 219.87 ? 757 TYR A CD1 1 
ATOM 5882 C CD2 . TYR A 1 757 ? 79.055  103.622 96.542  1.00 219.87 ? 757 TYR A CD2 1 
ATOM 5883 C CE1 . TYR A 1 757 ? 80.199  104.666 94.256  1.00 219.87 ? 757 TYR A CE1 1 
ATOM 5884 C CE2 . TYR A 1 757 ? 78.373  104.571 95.805  1.00 219.87 ? 757 TYR A CE2 1 
ATOM 5885 C CZ  . TYR A 1 757 ? 78.950  105.089 94.663  1.00 219.87 ? 757 TYR A CZ  1 
ATOM 5886 O OH  . TYR A 1 757 ? 78.274  106.035 93.927  1.00 219.87 ? 757 TYR A OH  1 
ATOM 5887 N N   . LEU A 1 758 ? 81.217  103.902 99.611  1.00 227.47 ? 758 LEU A N   1 
ATOM 5888 C CA  . LEU A 1 758 ? 80.819  105.110 100.325 1.00 227.47 ? 758 LEU A CA  1 
ATOM 5889 C C   . LEU A 1 758 ? 82.023  105.826 100.922 1.00 227.47 ? 758 LEU A C   1 
ATOM 5890 O O   . LEU A 1 758 ? 81.972  107.041 101.141 1.00 227.47 ? 758 LEU A O   1 
ATOM 5891 C CB  . LEU A 1 758 ? 79.793  104.772 101.410 1.00 227.47 ? 758 LEU A CB  1 
ATOM 5892 C CG  . LEU A 1 758 ? 80.196  103.869 102.581 1.00 227.47 ? 758 LEU A CG  1 
ATOM 5893 C CD1 . LEU A 1 758 ? 80.700  104.683 103.765 1.00 227.47 ? 758 LEU A CD1 1 
ATOM 5894 C CD2 . LEU A 1 758 ? 79.036  102.981 103.000 1.00 227.47 ? 758 LEU A CD2 1 
ATOM 5895 N N   . ASN A 1 759 ? 83.105  105.092 101.196 1.00 228.05 ? 759 ASN A N   1 
ATOM 5896 C CA  . ASN A 1 759 ? 84.314  105.715 101.725 1.00 228.05 ? 759 ASN A CA  1 
ATOM 5897 C C   . ASN A 1 759 ? 84.885  106.731 100.744 1.00 228.05 ? 759 ASN A C   1 
ATOM 5898 O O   . ASN A 1 759 ? 85.178  107.873 101.114 1.00 228.05 ? 759 ASN A O   1 
ATOM 5899 C CB  . ASN A 1 759 ? 85.349  104.642 102.060 1.00 228.05 ? 759 ASN A CB  1 
ATOM 5900 C CG  . ASN A 1 759 ? 84.993  103.862 103.306 1.00 228.05 ? 759 ASN A CG  1 
ATOM 5901 O OD1 . ASN A 1 759 ? 85.486  104.154 104.396 1.00 228.05 ? 759 ASN A OD1 1 
ATOM 5902 N ND2 . ASN A 1 759 ? 84.123  102.871 103.157 1.00 228.05 ? 759 ASN A ND2 1 
ATOM 5903 N N   . GLU A 1 760 ? 85.051  106.332 99.481  1.00 234.01 ? 760 GLU A N   1 
ATOM 5904 C CA  . GLU A 1 760 ? 85.509  107.289 98.481  1.00 234.01 ? 760 GLU A CA  1 
ATOM 5905 C C   . GLU A 1 760 ? 84.432  108.319 98.166  1.00 234.01 ? 760 GLU A C   1 
ATOM 5906 O O   . GLU A 1 760 ? 84.753  109.443 97.762  1.00 234.01 ? 760 GLU A O   1 
ATOM 5907 C CB  . GLU A 1 760 ? 85.956  106.565 97.210  1.00 234.01 ? 760 GLU A CB  1 
ATOM 5908 C CG  . GLU A 1 760 ? 84.858  105.815 96.477  1.00 234.01 ? 760 GLU A CG  1 
ATOM 5909 C CD  . GLU A 1 760 ? 85.325  105.248 95.148  1.00 234.01 ? 760 GLU A CD  1 
ATOM 5910 O OE1 . GLU A 1 760 ? 86.486  105.502 94.764  1.00 234.01 ? 760 GLU A OE1 1 
ATOM 5911 O OE2 . GLU A 1 760 ? 84.529  104.549 94.486  1.00 234.01 ? 760 GLU A OE2 1 
ATOM 5912 N N   . LEU A 1 761 ? 83.158  107.957 98.336  1.00 215.90 ? 761 LEU A N   1 
ATOM 5913 C CA  . LEU A 1 761 ? 82.078  108.918 98.133  1.00 215.90 ? 761 LEU A CA  1 
ATOM 5914 C C   . LEU A 1 761 ? 82.155  110.045 99.156  1.00 215.90 ? 761 LEU A C   1 
ATOM 5915 O O   . LEU A 1 761 ? 82.134  111.227 98.794  1.00 215.90 ? 761 LEU A O   1 
ATOM 5916 C CB  . LEU A 1 761 ? 80.725  108.208 98.207  1.00 215.90 ? 761 LEU A CB  1 
ATOM 5917 C CG  . LEU A 1 761 ? 79.579  108.704 97.318  1.00 215.90 ? 761 LEU A CG  1 
ATOM 5918 C CD1 . LEU A 1 761 ? 78.383  107.770 97.427  1.00 215.90 ? 761 LEU A CD1 1 
ATOM 5919 C CD2 . LEU A 1 761 ? 79.170  110.131 97.652  1.00 215.90 ? 761 LEU A CD2 1 
ATOM 5920 N N   . ARG A 1 762 ? 82.247  109.698 100.443 1.00 231.96 ? 762 ARG A N   1 
ATOM 5921 C CA  . ARG A 1 762 ? 82.400  110.729 101.464 1.00 231.96 ? 762 ARG A CA  1 
ATOM 5922 C C   . ARG A 1 762 ? 83.764  111.398 101.378 1.00 231.96 ? 762 ARG A C   1 
ATOM 5923 O O   . ARG A 1 762 ? 83.920  112.541 101.822 1.00 231.96 ? 762 ARG A O   1 
ATOM 5924 C CB  . ARG A 1 762 ? 82.174  110.141 102.859 1.00 231.96 ? 762 ARG A CB  1 
ATOM 5925 C CG  . ARG A 1 762 ? 83.156  109.056 103.264 1.00 231.96 ? 762 ARG A CG  1 
ATOM 5926 C CD  . ARG A 1 762 ? 82.788  108.467 104.619 1.00 231.96 ? 762 ARG A CD  1 
ATOM 5927 N NE  . ARG A 1 762 ? 81.372  108.122 104.697 1.00 231.96 ? 762 ARG A NE  1 
ATOM 5928 C CZ  . ARG A 1 762 ? 80.789  107.573 105.755 1.00 231.96 ? 762 ARG A CZ  1 
ATOM 5929 N NH1 . ARG A 1 762 ? 81.475  107.275 106.846 1.00 231.96 ? 762 ARG A NH1 1 
ATOM 5930 N NH2 . ARG A 1 762 ? 79.485  107.315 105.715 1.00 231.96 ? 762 ARG A NH2 1 
ATOM 5931 N N   . GLU A 1 763 ? 84.761  110.704 100.824 1.00 229.81 ? 763 GLU A N   1 
ATOM 5932 C CA  . GLU A 1 763 ? 86.043  111.343 100.552 1.00 229.81 ? 763 GLU A CA  1 
ATOM 5933 C C   . GLU A 1 763 ? 85.876  112.481 99.553  1.00 229.81 ? 763 GLU A C   1 
ATOM 5934 O O   . GLU A 1 763 ? 86.435  113.569 99.730  1.00 229.81 ? 763 GLU A O   1 
ATOM 5935 C CB  . GLU A 1 763 ? 87.044  110.312 100.029 1.00 229.81 ? 763 GLU A CB  1 
ATOM 5936 C CG  . GLU A 1 763 ? 88.406  110.389 100.687 1.00 229.81 ? 763 GLU A CG  1 
ATOM 5937 C CD  . GLU A 1 763 ? 88.904  111.812 100.819 1.00 229.81 ? 763 GLU A CD  1 
ATOM 5938 O OE1 . GLU A 1 763 ? 89.177  112.449 99.780  1.00 229.81 ? 763 GLU A OE1 1 
ATOM 5939 O OE2 . GLU A 1 763 ? 89.009  112.296 101.964 1.00 229.81 ? 763 GLU A OE2 1 
ATOM 5940 N N   . SER A 1 764 ? 85.104  112.242 98.490  1.00 218.89 ? 764 SER A N   1 
ATOM 5941 C CA  . SER A 1 764 ? 84.834  113.294 97.517  1.00 218.89 ? 764 SER A CA  1 
ATOM 5942 C C   . SER A 1 764 ? 83.998  114.409 98.130  1.00 218.89 ? 764 SER A C   1 
ATOM 5943 O O   . SER A 1 764 ? 84.133  115.578 97.751  1.00 218.89 ? 764 SER A O   1 
ATOM 5944 C CB  . SER A 1 764 ? 84.133  112.708 96.292  1.00 218.89 ? 764 SER A CB  1 
ATOM 5945 O OG  . SER A 1 764 ? 82.889  112.128 96.642  1.00 218.89 ? 764 SER A OG  1 
ATOM 5946 N N   . CYS A 1 765 ? 83.118  114.064 99.073  1.00 224.10 ? 765 CYS A N   1 
ATOM 5947 C CA  . CYS A 1 765 ? 82.319  115.083 99.746  1.00 224.10 ? 765 CYS A CA  1 
ATOM 5948 C C   . CYS A 1 765 ? 83.201  116.042 100.535 1.00 224.10 ? 765 CYS A C   1 
ATOM 5949 O O   . CYS A 1 765 ? 82.960  117.255 100.543 1.00 224.10 ? 765 CYS A O   1 
ATOM 5950 C CB  . CYS A 1 765 ? 81.290  114.422 100.663 1.00 224.10 ? 765 CYS A CB  1 
ATOM 5951 S SG  . CYS A 1 765 ? 80.014  113.471 99.804  1.00 224.10 ? 765 CYS A SG  1 
ATOM 5952 N N   . LEU A 1 766 ? 84.226  115.515 101.208 1.00 226.11 ? 766 LEU A N   1 
ATOM 5953 C CA  . LEU A 1 766 ? 85.097  116.359 102.020 1.00 226.11 ? 766 LEU A CA  1 
ATOM 5954 C C   . LEU A 1 766 ? 85.848  117.369 101.162 1.00 226.11 ? 766 LEU A C   1 
ATOM 5955 O O   . LEU A 1 766 ? 85.846  118.571 101.452 1.00 226.11 ? 766 LEU A O   1 
ATOM 5956 C CB  . LEU A 1 766 ? 86.076  115.489 102.808 1.00 226.11 ? 766 LEU A CB  1 
ATOM 5957 C CG  . LEU A 1 766 ? 85.461  114.541 103.837 1.00 226.11 ? 766 LEU A CG  1 
ATOM 5958 C CD1 . LEU A 1 766 ? 86.535  113.683 104.486 1.00 226.11 ? 766 LEU A CD1 1 
ATOM 5959 C CD2 . LEU A 1 766 ? 84.687  115.321 104.885 1.00 226.11 ? 766 LEU A CD2 1 
ATOM 5960 N N   . GLU A 1 767 ? 86.493  116.898 100.091 1.00 229.58 ? 767 GLU A N   1 
ATOM 5961 C CA  . GLU A 1 767 ? 87.312  117.787 99.273  1.00 229.58 ? 767 GLU A CA  1 
ATOM 5962 C C   . GLU A 1 767 ? 86.469  118.835 98.556  1.00 229.58 ? 767 GLU A C   1 
ATOM 5963 O O   . GLU A 1 767 ? 86.960  119.934 98.275  1.00 229.58 ? 767 GLU A O   1 
ATOM 5964 C CB  . GLU A 1 767 ? 88.139  116.971 98.276  1.00 229.58 ? 767 GLU A CB  1 
ATOM 5965 C CG  . GLU A 1 767 ? 87.329  116.094 97.341  1.00 229.58 ? 767 GLU A CG  1 
ATOM 5966 C CD  . GLU A 1 767 ? 86.883  116.835 96.101  1.00 229.58 ? 767 GLU A CD  1 
ATOM 5967 O OE1 . GLU A 1 767 ? 87.736  117.122 95.234  1.00 229.58 ? 767 GLU A OE1 1 
ATOM 5968 O OE2 . GLU A 1 767 ? 85.680  117.146 96.004  1.00 229.58 ? 767 GLU A OE2 1 
ATOM 5969 N N   . ALA A 1 768 ? 85.211  118.514 98.242  1.00 221.82 ? 768 ALA A N   1 
ATOM 5970 C CA  . ALA A 1 768 ? 84.322  119.513 97.659  1.00 221.82 ? 768 ALA A CA  1 
ATOM 5971 C C   . ALA A 1 768 ? 84.119  120.686 98.609  1.00 221.82 ? 768 ALA A C   1 
ATOM 5972 O O   . ALA A 1 768 ? 84.130  121.848 98.187  1.00 221.82 ? 768 ALA A O   1 
ATOM 5973 C CB  . ALA A 1 768 ? 82.982  118.875 97.295  1.00 221.82 ? 768 ALA A CB  1 
ATOM 5974 N N   . TYR A 1 769 ? 83.935  120.399 99.900  1.00 231.04 ? 769 TYR A N   1 
ATOM 5975 C CA  . TYR A 1 769 ? 83.771  121.463 100.884 1.00 231.04 ? 769 TYR A CA  1 
ATOM 5976 C C   . TYR A 1 769 ? 85.050  122.278 101.039 1.00 231.04 ? 769 TYR A C   1 
ATOM 5977 O O   . TYR A 1 769 ? 84.994  123.487 101.294 1.00 231.04 ? 769 TYR A O   1 
ATOM 5978 C CB  . TYR A 1 769 ? 83.337  120.870 102.224 1.00 231.04 ? 769 TYR A CB  1 
ATOM 5979 C CG  . TYR A 1 769 ? 82.007  120.155 102.157 1.00 231.04 ? 769 TYR A CG  1 
ATOM 5980 C CD1 . TYR A 1 769 ? 80.964  120.666 101.396 1.00 231.04 ? 769 TYR A CD1 1 
ATOM 5981 C CD2 . TYR A 1 769 ? 81.796  118.966 102.843 1.00 231.04 ? 769 TYR A CD2 1 
ATOM 5982 C CE1 . TYR A 1 769 ? 79.746  120.018 101.326 1.00 231.04 ? 769 TYR A CE1 1 
ATOM 5983 C CE2 . TYR A 1 769 ? 80.581  118.308 102.778 1.00 231.04 ? 769 TYR A CE2 1 
ATOM 5984 C CZ  . TYR A 1 769 ? 79.560  118.837 102.016 1.00 231.04 ? 769 TYR A CZ  1 
ATOM 5985 O OH  . TYR A 1 769 ? 78.347  118.189 101.948 1.00 231.04 ? 769 TYR A OH  1 
ATOM 5986 N N   . THR A 1 770 ? 86.211  121.634 100.897 1.00 230.03 ? 770 THR A N   1 
ATOM 5987 C CA  . THR A 1 770 ? 87.474  122.360 100.999 1.00 230.03 ? 770 THR A CA  1 
ATOM 5988 C C   . THR A 1 770 ? 87.607  123.399 99.893  1.00 230.03 ? 770 THR A C   1 
ATOM 5989 O O   . THR A 1 770 ? 88.063  124.522 100.138 1.00 230.03 ? 770 THR A O   1 
ATOM 5990 C CB  . THR A 1 770 ? 88.653  121.386 100.952 1.00 230.03 ? 770 THR A CB  1 
ATOM 5991 O OG1 . THR A 1 770 ? 88.693  120.741 99.672  1.00 230.03 ? 770 THR A OG1 1 
ATOM 5992 C CG2 . THR A 1 770 ? 88.526  120.334 102.043 1.00 230.03 ? 770 THR A CG2 1 
ATOM 5993 N N   . GLY A 1 771 ? 87.218  123.041 98.668  1.00 220.63 ? 771 GLY A N   1 
ATOM 5994 C CA  . GLY A 1 771 ? 87.385  123.957 97.551  1.00 220.63 ? 771 GLY A CA  1 
ATOM 5995 C C   . GLY A 1 771 ? 86.552  125.219 97.683  1.00 220.63 ? 771 GLY A C   1 
ATOM 5996 O O   . GLY A 1 771 ? 87.049  126.326 97.453  1.00 220.63 ? 771 GLY A O   1 
ATOM 5997 N N   . ILE A 1 772 ? 85.277  125.075 98.049  1.00 217.39 ? 772 ILE A N   1 
ATOM 5998 C CA  . ILE A 1 772 ? 84.412  126.245 98.163  1.00 217.39 ? 772 ILE A CA  1 
ATOM 5999 C C   . ILE A 1 772 ? 84.837  127.125 99.331  1.00 217.39 ? 772 ILE A C   1 
ATOM 6000 O O   . ILE A 1 772 ? 84.765  128.357 99.245  1.00 217.39 ? 772 ILE A O   1 
ATOM 6001 C CB  . ILE A 1 772 ? 82.938  125.817 98.278  1.00 217.39 ? 772 ILE A CB  1 
ATOM 6002 C CG1 . ILE A 1 772 ? 82.768  124.738 99.347  1.00 217.39 ? 772 ILE A CG1 1 
ATOM 6003 C CG2 . ILE A 1 772 ? 82.425  125.324 96.935  1.00 217.39 ? 772 ILE A CG2 1 
ATOM 6004 C CD1 . ILE A 1 772 ? 81.352  124.233 99.474  1.00 217.39 ? 772 ILE A CD1 1 
ATOM 6005 N N   . VAL A 1 773 ? 85.273  126.521 100.440 1.00 220.69 ? 773 VAL A N   1 
ATOM 6006 C CA  . VAL A 1 773 ? 85.806  127.308 101.548 1.00 220.69 ? 773 VAL A CA  1 
ATOM 6007 C C   . VAL A 1 773 ? 87.063  128.054 101.117 1.00 220.69 ? 773 VAL A C   1 
ATOM 6008 O O   . VAL A 1 773 ? 87.215  129.251 101.390 1.00 220.69 ? 773 VAL A O   1 
ATOM 6009 C CB  . VAL A 1 773 ? 86.071  126.405 102.767 1.00 220.69 ? 773 VAL A CB  1 
ATOM 6010 C CG1 . VAL A 1 773 ? 86.913  127.138 103.802 1.00 220.69 ? 773 VAL A CG1 1 
ATOM 6011 C CG2 . VAL A 1 773 ? 84.758  125.946 103.380 1.00 220.69 ? 773 VAL A CG2 1 
ATOM 6012 N N   . GLN A 1 774 ? 87.980  127.365 100.432 1.00 220.15 ? 774 GLN A N   1 
ATOM 6013 C CA  . GLN A 1 774 ? 89.184  128.024 99.937  1.00 220.15 ? 774 GLN A CA  1 
ATOM 6014 C C   . GLN A 1 774 ? 88.871  128.998 98.808  1.00 220.15 ? 774 GLN A C   1 
ATOM 6015 O O   . GLN A 1 774 ? 89.518  130.045 98.700  1.00 220.15 ? 774 GLN A O   1 
ATOM 6016 C CB  . GLN A 1 774 ? 90.204  126.984 99.471  1.00 220.15 ? 774 GLN A CB  1 
ATOM 6017 C CG  . GLN A 1 774 ? 90.903  126.246 100.602 1.00 220.15 ? 774 GLN A CG  1 
ATOM 6018 C CD  . GLN A 1 774 ? 91.905  127.114 101.340 1.00 220.15 ? 774 GLN A CD  1 
ATOM 6019 O OE1 . GLN A 1 774 ? 92.270  128.194 100.877 1.00 220.15 ? 774 GLN A OE1 1 
ATOM 6020 N NE2 . GLN A 1 774 ? 92.358  126.642 102.495 1.00 220.15 ? 774 GLN A NE2 1 
ATOM 6021 N N   . GLY A 1 775 ? 87.900  128.666 97.954  1.00 216.90 ? 775 GLY A N   1 
ATOM 6022 C CA  . GLY A 1 775 ? 87.563  129.553 96.852  1.00 216.90 ? 775 GLY A CA  1 
ATOM 6023 C C   . GLY A 1 775 ? 87.042  130.900 97.315  1.00 216.90 ? 775 GLY A C   1 
ATOM 6024 O O   . GLY A 1 775 ? 87.474  131.945 96.820  1.00 216.90 ? 775 GLY A O   1 
ATOM 6025 N N   . LEU A 1 776 ? 86.113  130.898 98.274  1.00 221.08 ? 776 LEU A N   1 
ATOM 6026 C CA  . LEU A 1 776 ? 85.597  132.153 98.806  1.00 221.08 ? 776 LEU A CA  1 
ATOM 6027 C C   . LEU A 1 776 ? 86.590  132.838 99.735  1.00 221.08 ? 776 LEU A C   1 
ATOM 6028 O O   . LEU A 1 776 ? 86.468  134.044 99.969  1.00 221.08 ? 776 LEU A O   1 
ATOM 6029 C CB  . LEU A 1 776 ? 84.277  131.914 99.541  1.00 221.08 ? 776 LEU A CB  1 
ATOM 6030 C CG  . LEU A 1 776 ? 83.131  131.329 98.715  1.00 221.08 ? 776 LEU A CG  1 
ATOM 6031 C CD1 . LEU A 1 776 ? 81.877  131.193 99.561  1.00 221.08 ? 776 LEU A CD1 1 
ATOM 6032 C CD2 . LEU A 1 776 ? 82.859  132.181 97.483  1.00 221.08 ? 776 LEU A CD2 1 
ATOM 6033 N N   . LYS A 1 777 ? 87.566  132.097 100.266 1.00 226.83 ? 777 LYS A N   1 
ATOM 6034 C CA  . LYS A 1 777 ? 88.553  132.696 101.160 1.00 226.83 ? 777 LYS A CA  1 
ATOM 6035 C C   . LYS A 1 777 ? 89.424  133.708 100.425 1.00 226.83 ? 777 LYS A C   1 
ATOM 6036 O O   . LYS A 1 777 ? 89.911  134.673 101.027 1.00 226.83 ? 777 LYS A O   1 
ATOM 6037 C CB  . LYS A 1 777 ? 89.414  131.601 101.790 1.00 226.83 ? 777 LYS A CB  1 
ATOM 6038 C CG  . LYS A 1 777 ? 90.355  132.082 102.883 1.00 226.83 ? 777 LYS A CG  1 
ATOM 6039 C CD  . LYS A 1 777 ? 91.167  130.924 103.442 1.00 226.83 ? 777 LYS A CD  1 
ATOM 6040 C CE  . LYS A 1 777 ? 90.262  129.799 103.913 1.00 226.83 ? 777 LYS A CE  1 
ATOM 6041 N NZ  . LYS A 1 777 ? 91.030  128.627 104.411 1.00 226.83 ? 777 LYS A NZ  1 
ATOM 6042 N N   . GLY A 1 778 ? 89.620  133.512 99.122  1.00 231.02 ? 778 GLY A N   1 
ATOM 6043 C CA  . GLY A 1 778 ? 90.428  134.405 98.317  1.00 231.02 ? 778 GLY A CA  1 
ATOM 6044 C C   . GLY A 1 778 ? 91.868  133.955 98.182  1.00 231.02 ? 778 GLY A C   1 
ATOM 6045 O O   . GLY A 1 778 ? 92.149  132.757 98.094  1.00 231.02 ? 778 GLY A O   1 
ATOM 6046 N N   . ASP A 1 779 ? 92.798  134.906 98.188  1.00 242.10 ? 779 ASP A N   1 
ATOM 6047 C CA  . ASP A 1 779 ? 94.209  134.605 98.006  1.00 242.10 ? 779 ASP A CA  1 
ATOM 6048 C C   . ASP A 1 779 ? 95.012  134.861 99.275  1.00 242.10 ? 779 ASP A C   1 
ATOM 6049 O O   . ASP A 1 779 ? 95.760  133.984 99.716  1.00 242.10 ? 779 ASP A O   1 
ATOM 6050 C CB  . ASP A 1 779 ? 94.762  135.413 96.823  1.00 242.10 ? 779 ASP A CB  1 
ATOM 6051 C CG  . ASP A 1 779 ? 93.982  135.169 95.536  1.00 242.10 ? 779 ASP A CG  1 
ATOM 6052 O OD1 . ASP A 1 779 ? 93.420  134.062 95.379  1.00 242.10 ? 779 ASP A OD1 1 
ATOM 6053 O OD2 . ASP A 1 779 ? 93.925  136.086 94.687  1.00 242.10 ? 779 ASP A OD2 1 
ATOM 6054 N N   . GLN A 1 780 ? 94.884  136.046 99.879  1.00 245.56 ? 780 GLN A N   1 
ATOM 6055 C CA  . GLN A 1 780 ? 95.654  136.355 101.080 1.00 245.56 ? 780 GLN A CA  1 
ATOM 6056 C C   . GLN A 1 780 ? 94.902  137.158 102.132 1.00 245.56 ? 780 GLN A C   1 
ATOM 6057 O O   . GLN A 1 780 ? 95.345  137.175 103.285 1.00 245.56 ? 780 GLN A O   1 
ATOM 6058 C CB  . GLN A 1 780 ? 96.935  137.120 100.705 1.00 245.56 ? 780 GLN A CB  1 
ATOM 6059 C CG  . GLN A 1 780 ? 96.725  138.612 100.464 1.00 245.56 ? 780 GLN A CG  1 
ATOM 6060 C CD  . GLN A 1 780 ? 95.770  138.891 99.322  1.00 245.56 ? 780 GLN A CD  1 
ATOM 6061 O OE1 . GLN A 1 780 ? 95.616  138.073 98.416  1.00 245.56 ? 780 GLN A OE1 1 
ATOM 6062 N NE2 . GLN A 1 780 ? 95.114  140.044 99.365  1.00 245.56 ? 780 GLN A NE2 1 
ATOM 6063 N N   . GLU A 1 781 ? 93.792  137.809 101.798 1.00 251.61 ? 781 GLU A N   1 
ATOM 6064 C CA  . GLU A 1 781 ? 93.117  138.697 102.736 1.00 251.61 ? 781 GLU A CA  1 
ATOM 6065 C C   . GLU A 1 781 ? 92.272  137.872 103.710 1.00 251.61 ? 781 GLU A C   1 
ATOM 6066 O O   . GLU A 1 781 ? 92.282  136.638 103.695 1.00 251.61 ? 781 GLU A O   1 
ATOM 6067 C CB  . GLU A 1 781 ? 92.285  139.725 101.974 1.00 251.61 ? 781 GLU A CB  1 
ATOM 6068 C CG  . GLU A 1 781 ? 92.040  141.025 102.720 1.00 251.61 ? 781 GLU A CG  1 
ATOM 6069 C CD  . GLU A 1 781 ? 93.302  141.843 102.908 1.00 251.61 ? 781 GLU A CD  1 
ATOM 6070 O OE1 . GLU A 1 781 ? 94.217  141.743 102.062 1.00 251.61 ? 781 GLU A OE1 1 
ATOM 6071 O OE2 . GLU A 1 781 ? 93.375  142.591 103.905 1.00 251.61 ? 781 GLU A OE2 1 
ATOM 6072 N N   . ASN A 1 782 ? 91.520  138.555 104.571 1.00 252.09 ? 782 ASN A N   1 
ATOM 6073 C CA  . ASN A 1 782 ? 90.702  137.897 105.580 1.00 252.09 ? 782 ASN A CA  1 
ATOM 6074 C C   . ASN A 1 782 ? 89.463  137.290 104.920 1.00 252.09 ? 782 ASN A C   1 
ATOM 6075 O O   . ASN A 1 782 ? 89.313  137.291 103.695 1.00 252.09 ? 782 ASN A O   1 
ATOM 6076 C CB  . ASN A 1 782 ? 90.344  138.882 106.690 1.00 252.09 ? 782 ASN A CB  1 
ATOM 6077 C CG  . ASN A 1 782 ? 89.555  140.072 106.183 1.00 252.09 ? 782 ASN A CG  1 
ATOM 6078 O OD1 . ASN A 1 782 ? 88.327  140.032 106.114 1.00 252.09 ? 782 ASN A OD1 1 
ATOM 6079 N ND2 . ASN A 1 782 ? 90.257  141.141 105.827 1.00 252.09 ? 782 ASN A ND2 1 
ATOM 6080 N N   . VAL A 1 783 ? 88.560  136.755 105.736 1.00 248.31 ? 783 VAL A N   1 
ATOM 6081 C CA  . VAL A 1 783 ? 87.378  136.070 105.225 1.00 248.31 ? 783 VAL A CA  1 
ATOM 6082 C C   . VAL A 1 783 ? 86.460  137.079 104.549 1.00 248.31 ? 783 VAL A C   1 
ATOM 6083 O O   . VAL A 1 783 ? 86.180  138.153 105.094 1.00 248.31 ? 783 VAL A O   1 
ATOM 6084 C CB  . VAL A 1 783 ? 86.653  135.317 106.351 1.00 248.31 ? 783 VAL A CB  1 
ATOM 6085 C CG1 . VAL A 1 783 ? 87.452  134.090 106.757 1.00 248.31 ? 783 VAL A CG1 1 
ATOM 6086 C CG2 . VAL A 1 783 ? 86.426  136.227 107.552 1.00 248.31 ? 783 VAL A CG2 1 
ATOM 6087 N N   . HIS A 1 784 ? 86.002  136.738 103.347 1.00 244.75 ? 784 HIS A N   1 
ATOM 6088 C CA  . HIS A 1 784 ? 85.090  137.592 102.612 1.00 244.75 ? 784 HIS A CA  1 
ATOM 6089 C C   . HIS A 1 784 ? 83.691  137.520 103.220 1.00 244.75 ? 784 HIS A C   1 
ATOM 6090 O O   . HIS A 1 784 ? 83.366  136.575 103.943 1.00 244.75 ? 784 HIS A O   1 
ATOM 6091 C CB  . HIS A 1 784 ? 85.049  137.178 101.142 1.00 244.75 ? 784 HIS A CB  1 
ATOM 6092 C CG  . HIS A 1 784 ? 86.334  137.411 100.411 1.00 244.75 ? 784 HIS A CG  1 
ATOM 6093 N ND1 . HIS A 1 784 ? 87.333  136.463 100.340 1.00 244.75 ? 784 HIS A ND1 1 
ATOM 6094 C CD2 . HIS A 1 784 ? 86.786  138.485 99.723  1.00 244.75 ? 784 HIS A CD2 1 
ATOM 6095 C CE1 . HIS A 1 784 ? 88.343  136.944 99.637  1.00 244.75 ? 784 HIS A CE1 1 
ATOM 6096 N NE2 . HIS A 1 784 ? 88.037  138.169 99.251  1.00 244.75 ? 784 HIS A NE2 1 
ATOM 6097 N N   . PRO A 1 785 ? 82.842  138.517 102.948 1.00 248.37 ? 785 PRO A N   1 
ATOM 6098 C CA  . PRO A 1 785 ? 81.445  138.442 103.403 1.00 248.37 ? 785 PRO A CA  1 
ATOM 6099 C C   . PRO A 1 785 ? 80.669  137.275 102.815 1.00 248.37 ? 785 PRO A C   1 
ATOM 6100 O O   . PRO A 1 785 ? 79.604  136.933 103.344 1.00 248.37 ? 785 PRO A O   1 
ATOM 6101 C CB  . PRO A 1 785 ? 80.854  139.786 102.945 1.00 248.37 ? 785 PRO A CB  1 
ATOM 6102 C CG  . PRO A 1 785 ? 81.776  140.271 101.872 1.00 248.37 ? 785 PRO A CG  1 
ATOM 6103 C CD  . PRO A 1 785 ? 83.133  139.799 102.283 1.00 248.37 ? 785 PRO A CD  1 
ATOM 6104 N N   . ASP A 1 786 ? 81.162  136.658 101.739 1.00 242.76 ? 786 ASP A N   1 
ATOM 6105 C CA  . ASP A 1 786 ? 80.515  135.493 101.149 1.00 242.76 ? 786 ASP A CA  1 
ATOM 6106 C C   . ASP A 1 786 ? 80.491  134.290 102.084 1.00 242.76 ? 786 ASP A C   1 
ATOM 6107 O O   . ASP A 1 786 ? 79.721  133.356 101.838 1.00 242.76 ? 786 ASP A O   1 
ATOM 6108 C CB  . ASP A 1 786 ? 81.221  135.114 99.846  1.00 242.76 ? 786 ASP A CB  1 
ATOM 6109 C CG  . ASP A 1 786 ? 81.559  136.322 98.994  1.00 242.76 ? 786 ASP A CG  1 
ATOM 6110 O OD1 . ASP A 1 786 ? 80.825  137.329 99.069  1.00 242.76 ? 786 ASP A OD1 1 
ATOM 6111 O OD2 . ASP A 1 786 ? 82.561  136.264 98.250  1.00 242.76 ? 786 ASP A OD2 1 
ATOM 6112 N N   . VAL A 1 787 ? 81.312  134.288 103.138 1.00 240.04 ? 787 VAL A N   1 
ATOM 6113 C CA  . VAL A 1 787 ? 81.366  133.154 104.054 1.00 240.04 ? 787 VAL A CA  1 
ATOM 6114 C C   . VAL A 1 787 ? 80.052  132.960 104.802 1.00 240.04 ? 787 VAL A C   1 
ATOM 6115 O O   . VAL A 1 787 ? 79.766  131.849 105.264 1.00 240.04 ? 787 VAL A O   1 
ATOM 6116 C CB  . VAL A 1 787 ? 82.541  133.323 105.039 1.00 240.04 ? 787 VAL A CB  1 
ATOM 6117 C CG1 . VAL A 1 787 ? 82.212  134.355 106.108 1.00 240.04 ? 787 VAL A CG1 1 
ATOM 6118 C CG2 . VAL A 1 787 ? 82.919  131.986 105.662 1.00 240.04 ? 787 VAL A CG2 1 
ATOM 6119 N N   . MET A 1 788 ? 79.237  134.010 104.932 1.00 248.41 ? 788 MET A N   1 
ATOM 6120 C CA  . MET A 1 788 ? 77.970  133.884 105.642 1.00 248.41 ? 788 MET A CA  1 
ATOM 6121 C C   . MET A 1 788 ? 76.955  133.047 104.875 1.00 248.41 ? 788 MET A C   1 
ATOM 6122 O O   . MET A 1 788 ? 76.002  132.546 105.481 1.00 248.41 ? 788 MET A O   1 
ATOM 6123 C CB  . MET A 1 788 ? 77.388  135.269 105.934 1.00 248.41 ? 788 MET A CB  1 
ATOM 6124 C CG  . MET A 1 788 ? 78.317  136.176 106.726 1.00 248.41 ? 788 MET A CG  1 
ATOM 6125 S SD  . MET A 1 788 ? 78.897  135.424 108.260 1.00 248.41 ? 788 MET A SD  1 
ATOM 6126 C CE  . MET A 1 788 ? 77.349  135.167 109.122 1.00 248.41 ? 788 MET A CE  1 
ATOM 6127 N N   . LEU A 1 789 ? 77.131  132.892 103.560 1.00 238.16 ? 789 LEU A N   1 
ATOM 6128 C CA  . LEU A 1 789 ? 76.216  132.058 102.787 1.00 238.16 ? 789 LEU A CA  1 
ATOM 6129 C C   . LEU A 1 789 ? 76.301  130.594 103.202 1.00 238.16 ? 789 LEU A C   1 
ATOM 6130 O O   . LEU A 1 789 ? 75.272  129.915 103.286 1.00 238.16 ? 789 LEU A O   1 
ATOM 6131 C CB  . LEU A 1 789 ? 76.501  132.202 101.291 1.00 238.16 ? 789 LEU A CB  1 
ATOM 6132 C CG  . LEU A 1 789 ? 75.973  133.449 100.571 1.00 238.16 ? 789 LEU A CG  1 
ATOM 6133 C CD1 . LEU A 1 789 ? 76.787  134.691 100.907 1.00 238.16 ? 789 LEU A CD1 1 
ATOM 6134 C CD2 . LEU A 1 789 ? 75.939  133.219 99.068  1.00 238.16 ? 789 LEU A CD2 1 
ATOM 6135 N N   . VAL A 1 790 ? 77.511  130.092 103.463 1.00 240.61 ? 790 VAL A N   1 
ATOM 6136 C CA  . VAL A 1 790 ? 77.701  128.724 103.930 1.00 240.61 ? 790 VAL A CA  1 
ATOM 6137 C C   . VAL A 1 790 ? 77.744  128.632 105.446 1.00 240.61 ? 790 VAL A C   1 
ATOM 6138 O O   . VAL A 1 790 ? 77.965  127.540 105.987 1.00 240.61 ? 790 VAL A O   1 
ATOM 6139 C CB  . VAL A 1 790 ? 78.978  128.107 103.326 1.00 240.61 ? 790 VAL A CB  1 
ATOM 6140 C CG1 . VAL A 1 790 ? 78.854  128.000 101.815 1.00 240.61 ? 790 VAL A CG1 1 
ATOM 6141 C CG2 . VAL A 1 790 ? 80.196  128.932 103.710 1.00 240.61 ? 790 VAL A CG2 1 
ATOM 6142 N N   . GLN A 1 791 ? 77.551  129.749 106.147 1.00 251.32 ? 791 GLN A N   1 
ATOM 6143 C CA  . GLN A 1 791 ? 77.588  129.728 107.607 1.00 251.32 ? 791 GLN A CA  1 
ATOM 6144 C C   . GLN A 1 791 ? 76.543  128.809 108.234 1.00 251.32 ? 791 GLN A C   1 
ATOM 6145 O O   . GLN A 1 791 ? 76.911  128.043 109.141 1.00 251.32 ? 791 GLN A O   1 
ATOM 6146 C CB  . GLN A 1 791 ? 77.455  131.162 108.141 1.00 251.32 ? 791 GLN A CB  1 
ATOM 6147 C CG  . GLN A 1 791 ? 77.646  131.301 109.644 1.00 251.32 ? 791 GLN A CG  1 
ATOM 6148 C CD  . GLN A 1 791 ? 76.359  131.111 110.423 1.00 251.32 ? 791 GLN A CD  1 
ATOM 6149 O OE1 . GLN A 1 791 ? 75.266  131.146 109.858 1.00 251.32 ? 791 GLN A OE1 1 
ATOM 6150 N NE2 . GLN A 1 791 ? 76.484  130.908 111.729 1.00 251.32 ? 791 GLN A NE2 1 
ATOM 6151 N N   . PRO A 1 792 ? 75.262  128.830 107.843 1.00 249.24 ? 792 PRO A N   1 
ATOM 6152 C CA  . PRO A 1 792 ? 74.303  127.897 108.459 1.00 249.24 ? 792 PRO A CA  1 
ATOM 6153 C C   . PRO A 1 792 ? 74.621  126.432 108.210 1.00 249.24 ? 792 PRO A C   1 
ATOM 6154 O O   . PRO A 1 792 ? 74.204  125.585 109.012 1.00 249.24 ? 792 PRO A O   1 
ATOM 6155 C CB  . PRO A 1 792 ? 72.965  128.288 107.816 1.00 249.24 ? 792 PRO A CB  1 
ATOM 6156 C CG  . PRO A 1 792 ? 73.336  128.964 106.547 1.00 249.24 ? 792 PRO A CG  1 
ATOM 6157 C CD  . PRO A 1 792 ? 74.600  129.702 106.854 1.00 249.24 ? 792 PRO A CD  1 
ATOM 6158 N N   . ARG A 1 793 ? 75.335  126.106 107.135 1.00 235.76 ? 793 ARG A N   1 
ATOM 6159 C CA  . ARG A 1 793 ? 75.608  124.722 106.775 1.00 235.76 ? 793 ARG A CA  1 
ATOM 6160 C C   . ARG A 1 793 ? 76.794  124.117 107.518 1.00 235.76 ? 793 ARG A C   1 
ATOM 6161 O O   . ARG A 1 793 ? 76.948  122.892 107.495 1.00 235.76 ? 793 ARG A O   1 
ATOM 6162 C CB  . ARG A 1 793 ? 75.846  124.609 105.264 1.00 235.76 ? 793 ARG A CB  1 
ATOM 6163 C CG  . ARG A 1 793 ? 74.622  124.172 104.468 1.00 235.76 ? 793 ARG A CG  1 
ATOM 6164 C CD  . ARG A 1 793 ? 73.412  125.048 104.757 1.00 235.76 ? 793 ARG A CD  1 
ATOM 6165 N NE  . ARG A 1 793 ? 73.620  126.430 104.341 1.00 235.76 ? 793 ARG A NE  1 
ATOM 6166 C CZ  . ARG A 1 793 ? 73.250  126.921 103.166 1.00 235.76 ? 793 ARG A CZ  1 
ATOM 6167 N NH1 . ARG A 1 793 ? 72.645  126.168 102.262 1.00 235.76 ? 793 ARG A NH1 1 
ATOM 6168 N NH2 . ARG A 1 793 ? 73.495  128.199 102.891 1.00 235.76 ? 793 ARG A NH2 1 
ATOM 6169 N N   . VAL A 1 794 ? 77.625  124.930 108.178 1.00 244.82 ? 794 VAL A N   1 
ATOM 6170 C CA  . VAL A 1 794 ? 78.816  124.393 108.832 1.00 244.82 ? 794 VAL A CA  1 
ATOM 6171 C C   . VAL A 1 794 ? 78.461  123.405 109.935 1.00 244.82 ? 794 VAL A C   1 
ATOM 6172 O O   . VAL A 1 794 ? 79.235  122.476 110.199 1.00 244.82 ? 794 VAL A O   1 
ATOM 6173 C CB  . VAL A 1 794 ? 79.710  125.524 109.381 1.00 244.82 ? 794 VAL A CB  1 
ATOM 6174 C CG1 . VAL A 1 794 ? 80.053  126.513 108.278 1.00 244.82 ? 794 VAL A CG1 1 
ATOM 6175 C CG2 . VAL A 1 794 ? 79.052  126.227 110.560 1.00 244.82 ? 794 VAL A CG2 1 
ATOM 6176 N N   . GLU A 1 795 ? 77.314  123.580 110.597 1.00 257.45 ? 795 GLU A N   1 
ATOM 6177 C CA  . GLU A 1 795 ? 76.868  122.588 111.568 1.00 257.45 ? 795 GLU A CA  1 
ATOM 6178 C C   . GLU A 1 795 ? 76.584  121.253 110.892 1.00 257.45 ? 795 GLU A C   1 
ATOM 6179 O O   . GLU A 1 795 ? 76.967  120.196 111.406 1.00 257.45 ? 795 GLU A O   1 
ATOM 6180 C CB  . GLU A 1 795 ? 75.628  123.095 112.305 1.00 257.45 ? 795 GLU A CB  1 
ATOM 6181 C CG  . GLU A 1 795 ? 74.925  122.045 113.155 1.00 257.45 ? 795 GLU A CG  1 
ATOM 6182 C CD  . GLU A 1 795 ? 75.742  121.611 114.357 1.00 257.45 ? 795 GLU A CD  1 
ATOM 6183 O OE1 . GLU A 1 795 ? 76.663  122.352 114.757 1.00 257.45 ? 795 GLU A OE1 1 
ATOM 6184 O OE2 . GLU A 1 795 ? 75.459  120.524 114.904 1.00 257.45 ? 795 GLU A OE2 1 
ATOM 6185 N N   . PHE A 1 796 ? 75.918  121.284 109.735 1.00 246.21 ? 796 PHE A N   1 
ATOM 6186 C CA  . PHE A 1 796 ? 75.649  120.054 108.997 1.00 246.21 ? 796 PHE A CA  1 
ATOM 6187 C C   . PHE A 1 796 ? 76.936  119.417 108.486 1.00 246.21 ? 796 PHE A C   1 
ATOM 6188 O O   . PHE A 1 796 ? 77.089  118.191 108.538 1.00 246.21 ? 796 PHE A O   1 
ATOM 6189 C CB  . PHE A 1 796 ? 74.694  120.334 107.838 1.00 246.21 ? 796 PHE A CB  1 
ATOM 6190 C CG  . PHE A 1 796 ? 74.491  119.160 106.927 1.00 246.21 ? 796 PHE A CG  1 
ATOM 6191 C CD1 . PHE A 1 796 ? 73.671  118.109 107.302 1.00 246.21 ? 796 PHE A CD1 1 
ATOM 6192 C CD2 . PHE A 1 796 ? 75.121  119.106 105.695 1.00 246.21 ? 796 PHE A CD2 1 
ATOM 6193 C CE1 . PHE A 1 796 ? 73.485  117.025 106.466 1.00 246.21 ? 796 PHE A CE1 1 
ATOM 6194 C CE2 . PHE A 1 796 ? 74.938  118.025 104.855 1.00 246.21 ? 796 PHE A CE2 1 
ATOM 6195 C CZ  . PHE A 1 796 ? 74.118  116.984 105.242 1.00 246.21 ? 796 PHE A CZ  1 
ATOM 6196 N N   . ILE A 1 797 ? 77.865  120.230 107.975 1.00 247.59 ? 797 ILE A N   1 
ATOM 6197 C CA  . ILE A 1 797 ? 79.126  119.693 107.469 1.00 247.59 ? 797 ILE A CA  1 
ATOM 6198 C C   . ILE A 1 797 ? 79.907  119.024 108.592 1.00 247.59 ? 797 ILE A C   1 
ATOM 6199 O O   . ILE A 1 797 ? 80.439  117.920 108.428 1.00 247.59 ? 797 ILE A O   1 
ATOM 6200 C CB  . ILE A 1 797 ? 79.950  120.804 106.789 1.00 247.59 ? 797 ILE A CB  1 
ATOM 6201 C CG1 . ILE A 1 797 ? 79.121  121.502 105.708 1.00 247.59 ? 797 ILE A CG1 1 
ATOM 6202 C CG2 . ILE A 1 797 ? 81.231  120.234 106.200 1.00 247.59 ? 797 ILE A CG2 1 
ATOM 6203 C CD1 . ILE A 1 797 ? 78.473  120.559 104.722 1.00 247.59 ? 797 ILE A CD1 1 
ATOM 6204 N N   . LEU A 1 798 ? 79.991  119.683 109.750 1.00 245.95 ? 798 LEU A N   1 
ATOM 6205 C CA  . LEU A 1 798 ? 80.605  119.054 110.913 1.00 245.95 ? 798 LEU A CA  1 
ATOM 6206 C C   . LEU A 1 798 ? 79.792  117.857 111.390 1.00 245.95 ? 798 LEU A C   1 
ATOM 6207 O O   . LEU A 1 798 ? 80.355  116.908 111.947 1.00 245.95 ? 798 LEU A O   1 
ATOM 6208 C CB  . LEU A 1 798 ? 80.767  120.075 112.039 1.00 245.95 ? 798 LEU A CB  1 
ATOM 6209 C CG  . LEU A 1 798 ? 81.848  119.776 113.080 1.00 245.95 ? 798 LEU A CG  1 
ATOM 6210 C CD1 . LEU A 1 798 ? 83.233  119.895 112.466 1.00 245.95 ? 798 LEU A CD1 1 
ATOM 6211 C CD2 . LEU A 1 798 ? 81.714  120.699 114.277 1.00 245.95 ? 798 LEU A CD2 1 
ATOM 6212 N N   . SER A 1 799 ? 78.472  117.886 111.189 1.00 256.73 ? 799 SER A N   1 
ATOM 6213 C CA  . SER A 1 799 ? 77.640  116.742 111.549 1.00 256.73 ? 799 SER A CA  1 
ATOM 6214 C C   . SER A 1 799 ? 77.905  115.555 110.632 1.00 256.73 ? 799 SER A C   1 
ATOM 6215 O O   . SER A 1 799 ? 77.852  114.400 111.072 1.00 256.73 ? 799 SER A O   1 
ATOM 6216 C CB  . SER A 1 799 ? 76.162  117.130 111.506 1.00 256.73 ? 799 SER A CB  1 
ATOM 6217 O OG  . SER A 1 799 ? 75.890  118.206 112.386 1.00 256.73 ? 799 SER A OG  1 
ATOM 6218 N N   . PHE A 1 800 ? 78.171  115.816 109.351 1.00 247.30 ? 800 PHE A N   1 
ATOM 6219 C CA  . PHE A 1 800 ? 78.439  114.725 108.421 1.00 247.30 ? 800 PHE A CA  1 
ATOM 6220 C C   . PHE A 1 800 ? 79.712  113.976 108.799 1.00 247.30 ? 800 PHE A C   1 
ATOM 6221 O O   . PHE A 1 800 ? 79.745  112.741 108.762 1.00 247.30 ? 800 PHE A O   1 
ATOM 6222 C CB  . PHE A 1 800 ? 78.525  115.260 106.992 1.00 247.30 ? 800 PHE A CB  1 
ATOM 6223 C CG  . PHE A 1 800 ? 78.640  114.186 105.950 1.00 247.30 ? 800 PHE A CG  1 
ATOM 6224 C CD1 . PHE A 1 800 ? 77.762  113.115 105.943 1.00 247.30 ? 800 PHE A CD1 1 
ATOM 6225 C CD2 . PHE A 1 800 ? 79.617  114.251 104.972 1.00 247.30 ? 800 PHE A CD2 1 
ATOM 6226 C CE1 . PHE A 1 800 ? 77.863  112.123 104.986 1.00 247.30 ? 800 PHE A CE1 1 
ATOM 6227 C CE2 . PHE A 1 800 ? 79.721  113.264 104.011 1.00 247.30 ? 800 PHE A CE2 1 
ATOM 6228 C CZ  . PHE A 1 800 ? 78.842  112.199 104.018 1.00 247.30 ? 800 PHE A CZ  1 
ATOM 6229 N N   . ILE A 1 801 ? 80.767  114.703 109.173 1.00 247.17 ? 801 ILE A N   1 
ATOM 6230 C CA  . ILE A 1 801 ? 81.988  114.039 109.617 1.00 247.17 ? 801 ILE A CA  1 
ATOM 6231 C C   . ILE A 1 801 ? 81.843  113.465 111.019 1.00 247.17 ? 801 ILE A C   1 
ATOM 6232 O O   . ILE A 1 801 ? 82.651  112.617 111.419 1.00 247.17 ? 801 ILE A O   1 
ATOM 6233 C CB  . ILE A 1 801 ? 83.195  114.990 109.565 1.00 247.17 ? 801 ILE A CB  1 
ATOM 6234 C CG1 . ILE A 1 801 ? 83.128  116.010 110.701 1.00 247.17 ? 801 ILE A CG1 1 
ATOM 6235 C CG2 . ILE A 1 801 ? 83.251  115.698 108.225 1.00 247.17 ? 801 ILE A CG2 1 
ATOM 6236 C CD1 . ILE A 1 801 ? 84.356  116.874 110.802 1.00 247.17 ? 801 ILE A CD1 1 
ATOM 6237 N N   . ASP A 1 802 ? 80.846  113.917 111.785 1.00 253.13 ? 802 ASP A N   1 
ATOM 6238 C CA  . ASP A 1 802 ? 80.556  113.286 113.068 1.00 253.13 ? 802 ASP A CA  1 
ATOM 6239 C C   . ASP A 1 802 ? 80.168  111.826 112.873 1.00 253.13 ? 802 ASP A C   1 
ATOM 6240 O O   . ASP A 1 802 ? 80.663  110.943 113.584 1.00 253.13 ? 802 ASP A O   1 
ATOM 6241 C CB  . ASP A 1 802 ? 79.445  114.057 113.784 1.00 253.13 ? 802 ASP A CB  1 
ATOM 6242 C CG  . ASP A 1 802 ? 79.255  113.622 115.228 1.00 253.13 ? 802 ASP A CG  1 
ATOM 6243 O OD1 . ASP A 1 802 ? 79.158  112.406 115.495 1.00 253.13 ? 802 ASP A OD1 1 
ATOM 6244 O OD2 . ASP A 1 802 ? 79.200  114.508 116.105 1.00 253.13 ? 802 ASP A OD2 1 
ATOM 6245 N N   . HIS A 1 803 ? 79.285  111.553 111.910 1.00 258.08 ? 803 HIS A N   1 
ATOM 6246 C CA  . HIS A 1 803 ? 78.938  110.173 111.589 1.00 258.08 ? 803 HIS A CA  1 
ATOM 6247 C C   . HIS A 1 803 ? 80.135  109.407 111.043 1.00 258.08 ? 803 HIS A C   1 
ATOM 6248 O O   . HIS A 1 803 ? 80.328  108.236 111.389 1.00 258.08 ? 803 HIS A O   1 
ATOM 6249 C CB  . HIS A 1 803 ? 77.786  110.137 110.587 1.00 258.08 ? 803 HIS A CB  1 
ATOM 6250 C CG  . HIS A 1 803 ? 77.365  108.753 110.203 1.00 258.08 ? 803 HIS A CG  1 
ATOM 6251 N ND1 . HIS A 1 803 ? 77.853  108.109 109.087 1.00 258.08 ? 803 HIS A ND1 1 
ATOM 6252 C CD2 . HIS A 1 803 ? 76.505  107.888 110.790 1.00 258.08 ? 803 HIS A CD2 1 
ATOM 6253 C CE1 . HIS A 1 803 ? 77.310  106.907 109.002 1.00 258.08 ? 803 HIS A CE1 1 
ATOM 6254 N NE2 . HIS A 1 803 ? 76.488  106.748 110.023 1.00 258.08 ? 803 HIS A NE2 1 
ATOM 6255 N N   . ILE A 1 804 ? 80.939  110.043 110.187 1.00 249.09 ? 804 ILE A N   1 
ATOM 6256 C CA  . ILE A 1 804 ? 82.123  109.386 109.642 1.00 249.09 ? 804 ILE A CA  1 
ATOM 6257 C C   . ILE A 1 804 ? 83.100  109.038 110.757 1.00 249.09 ? 804 ILE A C   1 
ATOM 6258 O O   . ILE A 1 804 ? 83.668  107.939 110.783 1.00 249.09 ? 804 ILE A O   1 
ATOM 6259 C CB  . ILE A 1 804 ? 82.781  110.274 108.570 1.00 249.09 ? 804 ILE A CB  1 
ATOM 6260 C CG1 . ILE A 1 804 ? 81.783  110.600 107.459 1.00 249.09 ? 804 ILE A CG1 1 
ATOM 6261 C CG2 . ILE A 1 804 ? 84.015  109.593 107.994 1.00 249.09 ? 804 ILE A CG2 1 
ATOM 6262 C CD1 . ILE A 1 804 ? 82.306  111.588 106.441 1.00 249.09 ? 804 ILE A CD1 1 
ATOM 6263 N N   . ALA A 1 805 ? 83.315  109.966 111.693 1.00 252.78 ? 805 ALA A N   1 
ATOM 6264 C CA  . ALA A 1 805 ? 84.184  109.685 112.830 1.00 252.78 ? 805 ALA A CA  1 
ATOM 6265 C C   . ALA A 1 805 ? 83.636  108.551 113.686 1.00 252.78 ? 805 ALA A C   1 
ATOM 6266 O O   . ALA A 1 805 ? 84.411  107.751 114.222 1.00 252.78 ? 805 ALA A O   1 
ATOM 6267 C CB  . ALA A 1 805 ? 84.373  110.946 113.672 1.00 252.78 ? 805 ALA A CB  1 
ATOM 6268 N N   . GLY A 1 806 ? 82.312  108.464 113.823 1.00 259.20 ? 806 GLY A N   1 
ATOM 6269 C CA  . GLY A 1 806 ? 81.712  107.379 114.578 1.00 259.20 ? 806 GLY A CA  1 
ATOM 6270 C C   . GLY A 1 806 ? 81.800  106.031 113.895 1.00 259.20 ? 806 GLY A C   1 
ATOM 6271 O O   . GLY A 1 806 ? 81.686  105.000 114.567 1.00 259.20 ? 806 GLY A O   1 
ATOM 6272 N N   . ASP A 1 807 ? 81.999  106.013 112.580 1.00 264.61 ? 807 ASP A N   1 
ATOM 6273 C CA  . ASP A 1 807 ? 82.145  104.763 111.854 1.00 264.61 ? 807 ASP A CA  1 
ATOM 6274 C C   . ASP A 1 807 ? 83.482  104.107 112.191 1.00 264.61 ? 807 ASP A C   1 
ATOM 6275 O O   . ASP A 1 807 ? 84.386  104.724 112.761 1.00 264.61 ? 807 ASP A O   1 
ATOM 6276 C CB  . ASP A 1 807 ? 82.031  104.998 110.348 1.00 264.61 ? 807 ASP A CB  1 
ATOM 6277 C CG  . ASP A 1 807 ? 80.686  105.571 109.948 1.00 264.61 ? 807 ASP A CG  1 
ATOM 6278 O OD1 . ASP A 1 807 ? 79.688  105.293 110.646 1.00 264.61 ? 807 ASP A OD1 1 
ATOM 6279 O OD2 . ASP A 1 807 ? 80.627  106.303 108.936 1.00 264.61 ? 807 ASP A OD2 1 
ATOM 6280 N N   . GLU A 1 808 ? 83.606  102.831 111.821 1.00 261.79 ? 808 GLU A N   1 
ATOM 6281 C CA  . GLU A 1 808 ? 84.810  102.063 112.111 1.00 261.79 ? 808 GLU A CA  1 
ATOM 6282 C C   . GLU A 1 808 ? 85.401  101.401 110.872 1.00 261.79 ? 808 GLU A C   1 
ATOM 6283 O O   . GLU A 1 808 ? 86.441  100.741 110.977 1.00 261.79 ? 808 GLU A O   1 
ATOM 6284 C CB  . GLU A 1 808 ? 84.529  101.002 113.182 1.00 261.79 ? 808 GLU A CB  1 
ATOM 6285 C CG  . GLU A 1 808 ? 84.221  101.577 114.557 1.00 261.79 ? 808 GLU A CG  1 
ATOM 6286 C CD  . GLU A 1 808 ? 85.382  102.365 115.136 1.00 261.79 ? 808 GLU A CD  1 
ATOM 6287 O OE1 . GLU A 1 808 ? 86.546  102.033 114.825 1.00 261.79 ? 808 GLU A OE1 1 
ATOM 6288 O OE2 . GLU A 1 808 ? 85.131  103.320 115.900 1.00 261.79 ? 808 GLU A OE2 1 
ATOM 6289 N N   . ASP A 1 809 ? 84.771  101.556 109.707 1.00 258.80 ? 809 ASP A N   1 
ATOM 6290 C CA  . ASP A 1 809 ? 85.359  101.037 108.477 1.00 258.80 ? 809 ASP A CA  1 
ATOM 6291 C C   . ASP A 1 809 ? 86.594  101.844 108.094 1.00 258.80 ? 809 ASP A C   1 
ATOM 6292 O O   . ASP A 1 809 ? 87.708  101.309 108.046 1.00 258.80 ? 809 ASP A O   1 
ATOM 6293 C CB  . ASP A 1 809 ? 84.321  101.057 107.352 1.00 258.80 ? 809 ASP A CB  1 
ATOM 6294 C CG  . ASP A 1 809 ? 84.848  100.465 106.062 1.00 258.80 ? 809 ASP A CG  1 
ATOM 6295 O OD1 . ASP A 1 809 ? 85.080  99.239  106.021 1.00 258.80 ? 809 ASP A OD1 1 
ATOM 6296 O OD2 . ASP A 1 809 ? 85.026  101.224 105.087 1.00 258.80 ? 809 ASP A OD2 1 
ATOM 6297 N N   . HIS A 1 810 ? 86.405  103.137 107.821 1.00 254.94 ? 810 HIS A N   1 
ATOM 6298 C CA  . HIS A 1 810 ? 87.484  104.108 107.656 1.00 254.94 ? 810 HIS A CA  1 
ATOM 6299 C C   . HIS A 1 810 ? 88.376  103.836 106.449 1.00 254.94 ? 810 HIS A C   1 
ATOM 6300 O O   . HIS A 1 810 ? 88.365  102.740 105.877 1.00 254.94 ? 810 HIS A O   1 
ATOM 6301 C CB  . HIS A 1 810 ? 88.340  104.172 108.927 1.00 254.94 ? 810 HIS A CB  1 
ATOM 6302 C CG  . HIS A 1 810 ? 87.643  104.797 110.095 1.00 254.94 ? 810 HIS A CG  1 
ATOM 6303 N ND1 . HIS A 1 810 ? 88.229  104.914 111.337 1.00 254.94 ? 810 HIS A ND1 1 
ATOM 6304 C CD2 . HIS A 1 810 ? 86.409  105.342 110.209 1.00 254.94 ? 810 HIS A CD2 1 
ATOM 6305 C CE1 . HIS A 1 810 ? 87.386  105.502 112.166 1.00 254.94 ? 810 HIS A CE1 1 
ATOM 6306 N NE2 . HIS A 1 810 ? 86.274  105.772 111.507 1.00 254.94 ? 810 HIS A NE2 1 
ATOM 6307 N N   . THR A 1 811 ? 89.140  104.850 106.051 1.00 245.70 ? 811 THR A N   1 
ATOM 6308 C CA  . THR A 1 811 ? 90.125  104.737 104.987 1.00 245.70 ? 811 THR A CA  1 
ATOM 6309 C C   . THR A 1 811 ? 91.133  105.864 105.164 1.00 245.70 ? 811 THR A C   1 
ATOM 6310 O O   . THR A 1 811 ? 90.772  106.993 105.506 1.00 245.70 ? 811 THR A O   1 
ATOM 6311 C CB  . THR A 1 811 ? 89.480  104.796 103.594 1.00 245.70 ? 811 THR A CB  1 
ATOM 6312 O OG1 . THR A 1 811 ? 88.489  103.766 103.477 1.00 245.70 ? 811 THR A OG1 1 
ATOM 6313 C CG2 . THR A 1 811 ? 90.526  104.603 102.506 1.00 245.70 ? 811 THR A CG2 1 
ATOM 6314 N N   . ASP A 1 812 ? 92.410  105.537 104.944 1.00 250.65 ? 812 ASP A N   1 
ATOM 6315 C CA  . ASP A 1 812 ? 93.472  106.521 105.131 1.00 250.65 ? 812 ASP A CA  1 
ATOM 6316 C C   . ASP A 1 812 ? 93.250  107.767 104.283 1.00 250.65 ? 812 ASP A C   1 
ATOM 6317 O O   . ASP A 1 812 ? 93.604  108.873 104.707 1.00 250.65 ? 812 ASP A O   1 
ATOM 6318 C CB  . ASP A 1 812 ? 94.831  105.895 104.818 1.00 250.65 ? 812 ASP A CB  1 
ATOM 6319 C CG  . ASP A 1 812 ? 95.230  104.839 105.830 1.00 250.65 ? 812 ASP A CG  1 
ATOM 6320 O OD1 . ASP A 1 812 ? 94.815  104.952 107.002 1.00 250.65 ? 812 ASP A OD1 1 
ATOM 6321 O OD2 . ASP A 1 812 ? 95.960  103.897 105.455 1.00 250.65 ? 812 ASP A OD2 1 
ATOM 6322 N N   . GLY A 1 813 ? 92.681  107.612 103.086 1.00 244.91 ? 813 GLY A N   1 
ATOM 6323 C CA  . GLY A 1 813 ? 92.312  108.775 102.298 1.00 244.91 ? 813 GLY A CA  1 
ATOM 6324 C C   . GLY A 1 813 ? 91.222  109.610 102.940 1.00 244.91 ? 813 GLY A C   1 
ATOM 6325 O O   . GLY A 1 813 ? 91.281  110.843 102.905 1.00 244.91 ? 813 GLY A O   1 
ATOM 6326 N N   . VAL A 1 814 ? 90.214  108.959 103.529 1.00 239.46 ? 814 VAL A N   1 
ATOM 6327 C CA  . VAL A 1 814 ? 89.103  109.686 104.140 1.00 239.46 ? 814 VAL A CA  1 
ATOM 6328 C C   . VAL A 1 814 ? 89.588  110.501 105.333 1.00 239.46 ? 814 VAL A C   1 
ATOM 6329 O O   . VAL A 1 814 ? 89.219  111.670 105.503 1.00 239.46 ? 814 VAL A O   1 
ATOM 6330 C CB  . VAL A 1 814 ? 87.981  108.712 104.543 1.00 239.46 ? 814 VAL A CB  1 
ATOM 6331 C CG1 . VAL A 1 814 ? 86.800  109.471 105.132 1.00 239.46 ? 814 VAL A CG1 1 
ATOM 6332 C CG2 . VAL A 1 814 ? 87.546  107.881 103.348 1.00 239.46 ? 814 VAL A CG2 1 
ATOM 6333 N N   . VAL A 1 815 ? 90.421  109.894 106.178 1.00 244.05 ? 815 VAL A N   1 
ATOM 6334 C CA  . VAL A 1 815 ? 90.873  110.576 107.385 1.00 244.05 ? 815 VAL A CA  1 
ATOM 6335 C C   . VAL A 1 815 ? 91.846  111.704 107.056 1.00 244.05 ? 815 VAL A C   1 
ATOM 6336 O O   . VAL A 1 815 ? 92.097  112.575 107.897 1.00 244.05 ? 815 VAL A O   1 
ATOM 6337 C CB  . VAL A 1 815 ? 91.493  109.563 108.362 1.00 244.05 ? 815 VAL A CB  1 
ATOM 6338 C CG1 . VAL A 1 815 ? 90.572  108.365 108.526 1.00 244.05 ? 815 VAL A CG1 1 
ATOM 6339 C CG2 . VAL A 1 815 ? 92.866  109.128 107.881 1.00 244.05 ? 815 VAL A CG2 1 
ATOM 6340 N N   . ALA A 1 816 ? 92.408  111.714 105.846 1.00 241.72 ? 816 ALA A N   1 
ATOM 6341 C CA  . ALA A 1 816 ? 93.360  112.759 105.485 1.00 241.72 ? 816 ALA A CA  1 
ATOM 6342 C C   . ALA A 1 816 ? 92.652  114.080 105.206 1.00 241.72 ? 816 ALA A C   1 
ATOM 6343 O O   . ALA A 1 816 ? 92.878  115.076 105.903 1.00 241.72 ? 816 ALA A O   1 
ATOM 6344 C CB  . ALA A 1 816 ? 94.184  112.322 104.274 1.00 241.72 ? 816 ALA A CB  1 
ATOM 6345 N N   . CYS A 1 817 ? 91.781  114.104 104.194 1.00 241.43 ? 817 CYS A N   1 
ATOM 6346 C CA  . CYS A 1 817 ? 91.127  115.347 103.795 1.00 241.43 ? 817 CYS A CA  1 
ATOM 6347 C C   . CYS A 1 817 ? 90.225  115.910 104.885 1.00 241.43 ? 817 CYS A C   1 
ATOM 6348 O O   . CYS A 1 817 ? 90.007  117.126 104.923 1.00 241.43 ? 817 CYS A O   1 
ATOM 6349 C CB  . CYS A 1 817 ? 90.320  115.130 102.516 1.00 241.43 ? 817 CYS A CB  1 
ATOM 6350 S SG  . CYS A 1 817 ? 89.602  116.634 101.821 1.00 241.43 ? 817 CYS A SG  1 
ATOM 6351 N N   . ALA A 1 818 ? 89.691  115.057 105.762 1.00 241.43 ? 818 ALA A N   1 
ATOM 6352 C CA  . ALA A 1 818 ? 88.907  115.557 106.885 1.00 241.43 ? 818 ALA A CA  1 
ATOM 6353 C C   . ALA A 1 818 ? 89.750  116.450 107.783 1.00 241.43 ? 818 ALA A C   1 
ATOM 6354 O O   . ALA A 1 818 ? 89.295  117.516 108.213 1.00 241.43 ? 818 ALA A O   1 
ATOM 6355 C CB  . ALA A 1 818 ? 88.322  114.391 107.680 1.00 241.43 ? 818 ALA A CB  1 
ATOM 6356 N N   . ALA A 1 819 ? 90.985  116.035 108.072 1.00 245.94 ? 819 ALA A N   1 
ATOM 6357 C CA  . ALA A 1 819 ? 91.883  116.876 108.856 1.00 245.94 ? 819 ALA A CA  1 
ATOM 6358 C C   . ALA A 1 819 ? 92.202  118.174 108.125 1.00 245.94 ? 819 ALA A C   1 
ATOM 6359 O O   . ALA A 1 819 ? 92.242  119.246 108.740 1.00 245.94 ? 819 ALA A O   1 
ATOM 6360 C CB  . ALA A 1 819 ? 93.165  116.112 109.185 1.00 245.94 ? 819 ALA A CB  1 
ATOM 6361 N N   . GLY A 1 820 ? 92.441  118.095 106.814 1.00 245.89 ? 820 GLY A N   1 
ATOM 6362 C CA  . GLY A 1 820 ? 92.680  119.303 106.042 1.00 245.89 ? 820 GLY A CA  1 
ATOM 6363 C C   . GLY A 1 820 ? 91.476  120.224 106.006 1.00 245.89 ? 820 GLY A C   1 
ATOM 6364 O O   . GLY A 1 820 ? 91.618  121.448 106.068 1.00 245.89 ? 820 GLY A O   1 
ATOM 6365 N N   . LEU A 1 821 ? 90.275  119.650 105.895 1.00 238.75 ? 821 LEU A N   1 
ATOM 6366 C CA  . LEU A 1 821 ? 89.059  120.457 105.905 1.00 238.75 ? 821 LEU A CA  1 
ATOM 6367 C C   . LEU A 1 821 ? 88.872  121.178 107.233 1.00 238.75 ? 821 LEU A C   1 
ATOM 6368 O O   . LEU A 1 821 ? 88.383  122.314 107.254 1.00 238.75 ? 821 LEU A O   1 
ATOM 6369 C CB  . LEU A 1 821 ? 87.844  119.581 105.598 1.00 238.75 ? 821 LEU A CB  1 
ATOM 6370 C CG  . LEU A 1 821 ? 86.466  120.241 105.693 1.00 238.75 ? 821 LEU A CG  1 
ATOM 6371 C CD1 . LEU A 1 821 ? 86.369  121.452 104.778 1.00 238.75 ? 821 LEU A CD1 1 
ATOM 6372 C CD2 . LEU A 1 821 ? 85.373  119.235 105.370 1.00 238.75 ? 821 LEU A CD2 1 
ATOM 6373 N N   . ILE A 1 822 ? 89.252  120.540 108.344 1.00 248.15 ? 822 ILE A N   1 
ATOM 6374 C CA  . ILE A 1 822 ? 89.121  121.177 109.652 1.00 248.15 ? 822 ILE A CA  1 
ATOM 6375 C C   . ILE A 1 822 ? 89.931  122.466 109.701 1.00 248.15 ? 822 ILE A C   1 
ATOM 6376 O O   . ILE A 1 822 ? 89.456  123.493 110.200 1.00 248.15 ? 822 ILE A O   1 
ATOM 6377 C CB  . ILE A 1 822 ? 89.527  120.196 110.771 1.00 248.15 ? 822 ILE A CB  1 
ATOM 6378 C CG1 . ILE A 1 822 ? 88.285  119.572 111.411 1.00 248.15 ? 822 ILE A CG1 1 
ATOM 6379 C CG2 . ILE A 1 822 ? 90.365  120.888 111.839 1.00 248.15 ? 822 ILE A CG2 1 
ATOM 6380 C CD1 . ILE A 1 822 ? 87.408  118.810 110.449 1.00 248.15 ? 822 ILE A CD1 1 
ATOM 6381 N N   . GLY A 1 823 ? 91.158  122.440 109.177 1.00 253.29 ? 823 GLY A N   1 
ATOM 6382 C CA  . GLY A 1 823 ? 91.952  123.656 109.122 1.00 253.29 ? 823 GLY A CA  1 
ATOM 6383 C C   . GLY A 1 823 ? 91.298  124.737 108.283 1.00 253.29 ? 823 GLY A C   1 
ATOM 6384 O O   . GLY A 1 823 ? 91.334  125.918 108.639 1.00 253.29 ? 823 GLY A O   1 
ATOM 6385 N N   . ASP A 1 824 ? 90.698  124.351 107.155 1.00 253.66 ? 824 ASP A N   1 
ATOM 6386 C CA  . ASP A 1 824 ? 89.963  125.314 106.341 1.00 253.66 ? 824 ASP A CA  1 
ATOM 6387 C C   . ASP A 1 824 ? 88.757  125.865 107.092 1.00 253.66 ? 824 ASP A C   1 
ATOM 6388 O O   . ASP A 1 824 ? 88.483  127.070 107.038 1.00 253.66 ? 824 ASP A O   1 
ATOM 6389 C CB  . ASP A 1 824 ? 89.531  124.666 105.026 1.00 253.66 ? 824 ASP A CB  1 
ATOM 6390 C CG  . ASP A 1 824 ? 90.702  124.111 104.239 1.00 253.66 ? 824 ASP A CG  1 
ATOM 6391 O OD1 . ASP A 1 824 ? 91.848  124.218 104.723 1.00 253.66 ? 824 ASP A OD1 1 
ATOM 6392 O OD2 . ASP A 1 824 ? 90.479  123.566 103.138 1.00 253.66 ? 824 ASP A OD2 1 
ATOM 6393 N N   . LEU A 1 825 ? 88.022  124.998 107.793 1.00 258.44 ? 825 LEU A N   1 
ATOM 6394 C CA  . LEU A 1 825 ? 86.889  125.461 108.587 1.00 258.44 ? 825 LEU A CA  1 
ATOM 6395 C C   . LEU A 1 825 ? 87.338  126.336 109.750 1.00 258.44 ? 825 LEU A C   1 
ATOM 6396 O O   . LEU A 1 825 ? 86.660  127.314 110.084 1.00 258.44 ? 825 LEU A O   1 
ATOM 6397 C CB  . LEU A 1 825 ? 86.079  124.270 109.099 1.00 258.44 ? 825 LEU A CB  1 
ATOM 6398 C CG  . LEU A 1 825 ? 85.366  123.431 108.036 1.00 258.44 ? 825 LEU A CG  1 
ATOM 6399 C CD1 . LEU A 1 825 ? 84.537  122.334 108.686 1.00 258.44 ? 825 LEU A CD1 1 
ATOM 6400 C CD2 . LEU A 1 825 ? 84.499  124.311 107.149 1.00 258.44 ? 825 LEU A CD2 1 
ATOM 6401 N N   . CYS A 1 826 ? 88.468  126.002 110.378 1.00 259.95 ? 826 CYS A N   1 
ATOM 6402 C CA  . CYS A 1 826 ? 89.001  126.852 111.437 1.00 259.95 ? 826 CYS A CA  1 
ATOM 6403 C C   . CYS A 1 826 ? 89.372  128.228 110.900 1.00 259.95 ? 826 CYS A C   1 
ATOM 6404 O O   . CYS A 1 826 ? 89.134  129.245 111.562 1.00 259.95 ? 826 CYS A O   1 
ATOM 6405 C CB  . CYS A 1 826 ? 90.211  126.185 112.090 1.00 259.95 ? 826 CYS A CB  1 
ATOM 6406 S SG  . CYS A 1 826 ? 89.841  124.678 113.017 1.00 259.95 ? 826 CYS A SG  1 
ATOM 6407 N N   . THR A 1 827 ? 89.962  128.278 109.704 1.00 253.64 ? 827 THR A N   1 
ATOM 6408 C CA  . THR A 1 827 ? 90.263  129.562 109.081 1.00 253.64 ? 827 THR A CA  1 
ATOM 6409 C C   . THR A 1 827 ? 88.992  130.313 108.707 1.00 253.64 ? 827 THR A C   1 
ATOM 6410 O O   . THR A 1 827 ? 88.966  131.549 108.753 1.00 253.64 ? 827 THR A O   1 
ATOM 6411 C CB  . THR A 1 827 ? 91.136  129.355 107.841 1.00 253.64 ? 827 THR A CB  1 
ATOM 6412 O OG1 . THR A 1 827 ? 92.219  128.470 108.157 1.00 253.64 ? 827 THR A OG1 1 
ATOM 6413 C CG2 . THR A 1 827 ? 91.701  130.683 107.356 1.00 253.64 ? 827 THR A CG2 1 
ATOM 6414 N N   . ALA A 1 828 ? 87.933  129.587 108.339 1.00 255.28 ? 828 ALA A N   1 
ATOM 6415 C CA  . ALA A 1 828 ? 86.690  130.227 107.923 1.00 255.28 ? 828 ALA A CA  1 
ATOM 6416 C C   . ALA A 1 828 ? 86.094  131.066 109.047 1.00 255.28 ? 828 ALA A C   1 
ATOM 6417 O O   . ALA A 1 828 ? 85.849  132.266 108.876 1.00 255.28 ? 828 ALA A O   1 
ATOM 6418 C CB  . ALA A 1 828 ? 85.692  129.170 107.448 1.00 255.28 ? 828 ALA A CB  1 
ATOM 6419 N N   . PHE A 1 829 ? 85.850  130.455 110.203 1.00 256.50 ? 829 PHE A N   1 
ATOM 6420 C CA  . PHE A 1 829 ? 85.230  131.153 111.323 1.00 256.50 ? 829 PHE A CA  1 
ATOM 6421 C C   . PHE A 1 829 ? 86.114  131.190 112.559 1.00 256.50 ? 829 PHE A C   1 
ATOM 6422 O O   . PHE A 1 829 ? 86.415  132.278 113.064 1.00 256.50 ? 829 PHE A O   1 
ATOM 6423 C CB  . PHE A 1 829 ? 83.877  130.508 111.657 1.00 256.50 ? 829 PHE A CB  1 
ATOM 6424 C CG  . PHE A 1 829 ? 82.879  130.587 110.538 1.00 256.50 ? 829 PHE A CG  1 
ATOM 6425 C CD1 . PHE A 1 829 ? 82.088  131.712 110.376 1.00 256.50 ? 829 PHE A CD1 1 
ATOM 6426 C CD2 . PHE A 1 829 ? 82.736  129.539 109.644 1.00 256.50 ? 829 PHE A CD2 1 
ATOM 6427 C CE1 . PHE A 1 829 ? 81.171  131.791 109.344 1.00 256.50 ? 829 PHE A CE1 1 
ATOM 6428 C CE2 . PHE A 1 829 ? 81.820  129.611 108.610 1.00 256.50 ? 829 PHE A CE2 1 
ATOM 6429 C CZ  . PHE A 1 829 ? 81.037  130.738 108.461 1.00 256.50 ? 829 PHE A CZ  1 
ATOM 6430 N N   . GLY A 1 830 ? 86.547  130.037 113.059 1.00 258.53 ? 830 GLY A N   1 
ATOM 6431 C CA  . GLY A 1 830 ? 87.383  130.012 114.243 1.00 258.53 ? 830 GLY A CA  1 
ATOM 6432 C C   . GLY A 1 830 ? 86.606  129.889 115.538 1.00 258.53 ? 830 GLY A C   1 
ATOM 6433 O O   . GLY A 1 830 ? 86.219  128.784 115.932 1.00 258.53 ? 830 GLY A O   1 
ATOM 6434 N N   . LYS A 1 831 ? 86.382  131.020 116.214 1.00 259.11 ? 831 LYS A N   1 
ATOM 6435 C CA  . LYS A 1 831 ? 85.652  131.005 117.478 1.00 259.11 ? 831 LYS A CA  1 
ATOM 6436 C C   . LYS A 1 831 ? 84.244  130.446 117.313 1.00 259.11 ? 831 LYS A C   1 
ATOM 6437 O O   . LYS A 1 831 ? 83.737  129.774 118.219 1.00 259.11 ? 831 LYS A O   1 
ATOM 6438 C CB  . LYS A 1 831 ? 85.598  132.415 118.072 1.00 259.11 ? 831 LYS A CB  1 
ATOM 6439 C CG  . LYS A 1 831 ? 84.781  132.523 119.352 1.00 259.11 ? 831 LYS A CG  1 
ATOM 6440 C CD  . LYS A 1 831 ? 85.352  131.642 120.451 1.00 259.11 ? 831 LYS A CD  1 
ATOM 6441 C CE  . LYS A 1 831 ? 84.345  131.434 121.570 1.00 259.11 ? 831 LYS A CE  1 
ATOM 6442 N NZ  . LYS A 1 831 ? 83.122  130.734 121.085 1.00 259.11 ? 831 LYS A NZ  1 
ATOM 6443 N N   . ASP A 1 832 ? 83.599  130.710 116.174 1.00 259.31 ? 832 ASP A N   1 
ATOM 6444 C CA  . ASP A 1 832 ? 82.251  130.198 115.949 1.00 259.31 ? 832 ASP A CA  1 
ATOM 6445 C C   . ASP A 1 832 ? 82.221  128.674 115.930 1.00 259.31 ? 832 ASP A C   1 
ATOM 6446 O O   . ASP A 1 832 ? 81.304  128.068 116.497 1.00 259.31 ? 832 ASP A O   1 
ATOM 6447 C CB  . ASP A 1 832 ? 81.688  130.755 114.642 1.00 259.31 ? 832 ASP A CB  1 
ATOM 6448 C CG  . ASP A 1 832 ? 81.728  132.269 114.589 1.00 259.31 ? 832 ASP A CG  1 
ATOM 6449 O OD1 . ASP A 1 832 ? 81.654  132.904 115.661 1.00 259.31 ? 832 ASP A OD1 1 
ATOM 6450 O OD2 . ASP A 1 832 ? 81.834  132.825 113.475 1.00 259.31 ? 832 ASP A OD2 1 
ATOM 6451 N N   . VAL A 1 833 ? 83.207  128.040 115.292 1.00 261.01 ? 833 VAL A N   1 
ATOM 6452 C CA  . VAL A 1 833 ? 83.278  126.585 115.227 1.00 261.01 ? 833 VAL A CA  1 
ATOM 6453 C C   . VAL A 1 833 ? 83.760  125.968 116.533 1.00 261.01 ? 833 VAL A C   1 
ATOM 6454 O O   . VAL A 1 833 ? 83.632  124.750 116.717 1.00 261.01 ? 833 VAL A O   1 
ATOM 6455 C CB  . VAL A 1 833 ? 84.178  126.131 114.059 1.00 261.01 ? 833 VAL A CB  1 
ATOM 6456 C CG1 . VAL A 1 833 ? 83.821  124.715 113.618 1.00 261.01 ? 833 VAL A CG1 1 
ATOM 6457 C CG2 . VAL A 1 833 ? 84.067  127.099 112.893 1.00 261.01 ? 833 VAL A CG2 1 
ATOM 6458 N N   . LEU A 1 834 ? 84.304  126.774 117.450 1.00 265.79 ? 834 LEU A N   1 
ATOM 6459 C CA  . LEU A 1 834 ? 84.814  126.233 118.707 1.00 265.79 ? 834 LEU A CA  1 
ATOM 6460 C C   . LEU A 1 834 ? 83.708  125.574 119.523 1.00 265.79 ? 834 LEU A C   1 
ATOM 6461 O O   . LEU A 1 834 ? 83.908  124.492 120.085 1.00 265.79 ? 834 LEU A O   1 
ATOM 6462 C CB  . LEU A 1 834 ? 85.492  127.335 119.519 1.00 265.79 ? 834 LEU A CB  1 
ATOM 6463 C CG  . LEU A 1 834 ? 86.973  127.565 119.223 1.00 265.79 ? 834 LEU A CG  1 
ATOM 6464 C CD1 . LEU A 1 834 ? 87.518  128.689 120.086 1.00 265.79 ? 834 LEU A CD1 1 
ATOM 6465 C CD2 . LEU A 1 834 ? 87.755  126.283 119.451 1.00 265.79 ? 834 LEU A CD2 1 
ATOM 6466 N N   . LYS A 1 835 ? 82.540  126.212 119.609 1.00 272.92 ? 835 LYS A N   1 
ATOM 6467 C CA  . LYS A 1 835 ? 81.421  125.584 120.302 1.00 272.92 ? 835 LYS A CA  1 
ATOM 6468 C C   . LYS A 1 835 ? 80.925  124.353 119.553 1.00 272.92 ? 835 LYS A C   1 
ATOM 6469 O O   . LYS A 1 835 ? 80.516  123.369 120.180 1.00 272.92 ? 835 LYS A O   1 
ATOM 6470 C CB  . LYS A 1 835 ? 80.284  126.587 120.490 1.00 272.92 ? 835 LYS A CB  1 
ATOM 6471 C CG  . LYS A 1 835 ? 79.161  126.084 121.382 1.00 272.92 ? 835 LYS A CG  1 
ATOM 6472 C CD  . LYS A 1 835 ? 79.645  125.870 122.807 1.00 272.92 ? 835 LYS A CD  1 
ATOM 6473 C CE  . LYS A 1 835 ? 79.227  124.508 123.337 1.00 272.92 ? 835 LYS A CE  1 
ATOM 6474 N NZ  . LYS A 1 835 ? 79.845  123.402 122.556 1.00 272.92 ? 835 LYS A NZ  1 
ATOM 6475 N N   . LEU A 1 836 ? 80.950  124.394 118.219 1.00 263.96 ? 836 LEU A N   1 
ATOM 6476 C CA  . LEU A 1 836 ? 80.476  123.262 117.428 1.00 263.96 ? 836 LEU A CA  1 
ATOM 6477 C C   . LEU A 1 836 ? 81.367  122.038 117.607 1.00 263.96 ? 836 LEU A C   1 
ATOM 6478 O O   . LEU A 1 836 ? 80.865  120.920 117.776 1.00 263.96 ? 836 LEU A O   1 
ATOM 6479 C CB  . LEU A 1 836 ? 80.389  123.654 115.952 1.00 263.96 ? 836 LEU A CB  1 
ATOM 6480 C CG  . LEU A 1 836 ? 79.137  124.392 115.465 1.00 263.96 ? 836 LEU A CG  1 
ATOM 6481 C CD1 . LEU A 1 836 ? 79.002  125.775 116.092 1.00 263.96 ? 836 LEU A CD1 1 
ATOM 6482 C CD2 . LEU A 1 836 ? 79.137  124.489 113.946 1.00 263.96 ? 836 LEU A CD2 1 
ATOM 6483 N N   . VAL A 1 837 ? 82.690  122.223 117.570 1.00 269.76 ? 837 VAL A N   1 
ATOM 6484 C CA  . VAL A 1 837 ? 83.597  121.083 117.683 1.00 269.76 ? 837 VAL A CA  1 
ATOM 6485 C C   . VAL A 1 837 ? 83.586  120.467 119.077 1.00 269.76 ? 837 VAL A C   1 
ATOM 6486 O O   . VAL A 1 837 ? 83.744  119.246 119.204 1.00 269.76 ? 837 VAL A O   1 
ATOM 6487 C CB  . VAL A 1 837 ? 85.032  121.469 117.280 1.00 269.76 ? 837 VAL A CB  1 
ATOM 6488 C CG1 . VAL A 1 837 ? 85.082  121.859 115.809 1.00 269.76 ? 837 VAL A CG1 1 
ATOM 6489 C CG2 . VAL A 1 837 ? 85.563  122.595 118.153 1.00 269.76 ? 837 VAL A CG2 1 
ATOM 6490 N N   . GLU A 1 838 ? 83.412  121.273 120.128 1.00 275.58 ? 838 GLU A N   1 
ATOM 6491 C CA  . GLU A 1 838 ? 83.361  120.746 121.487 1.00 275.58 ? 838 GLU A CA  1 
ATOM 6492 C C   . GLU A 1 838 ? 82.176  119.818 121.716 1.00 275.58 ? 838 GLU A C   1 
ATOM 6493 O O   . GLU A 1 838 ? 82.250  118.945 122.587 1.00 275.58 ? 838 GLU A O   1 
ATOM 6494 C CB  . GLU A 1 838 ? 83.318  121.895 122.498 1.00 275.58 ? 838 GLU A CB  1 
ATOM 6495 C CG  . GLU A 1 838 ? 84.617  122.679 122.603 1.00 275.58 ? 838 GLU A CG  1 
ATOM 6496 C CD  . GLU A 1 838 ? 84.511  123.861 123.546 1.00 275.58 ? 838 GLU A CD  1 
ATOM 6497 O OE1 . GLU A 1 838 ? 83.405  124.110 124.071 1.00 275.58 ? 838 GLU A OE1 1 
ATOM 6498 O OE2 . GLU A 1 838 ? 85.535  124.543 123.761 1.00 275.58 ? 838 GLU A OE2 1 
ATOM 6499 N N   . ALA A 1 839 ? 81.091  119.981 120.956 1.00 269.56 ? 839 ALA A N   1 
ATOM 6500 C CA  . ALA A 1 839 ? 79.945  119.090 121.091 1.00 269.56 ? 839 ALA A CA  1 
ATOM 6501 C C   . ALA A 1 839 ? 80.148  117.771 120.358 1.00 269.56 ? 839 ALA A C   1 
ATOM 6502 O O   . ALA A 1 839 ? 79.312  116.870 120.486 1.00 269.56 ? 839 ALA A O   1 
ATOM 6503 C CB  . ALA A 1 839 ? 78.677  119.777 120.581 1.00 269.56 ? 839 ALA A CB  1 
ATOM 6504 N N   . ARG A 1 840 ? 81.229  117.637 119.594 1.00 262.83 ? 840 ARG A N   1 
ATOM 6505 C CA  . ARG A 1 840 ? 81.500  116.427 118.818 1.00 262.83 ? 840 ARG A CA  1 
ATOM 6506 C C   . ARG A 1 840 ? 82.867  115.878 119.198 1.00 262.83 ? 840 ARG A C   1 
ATOM 6507 O O   . ARG A 1 840 ? 83.882  116.248 118.581 1.00 262.83 ? 840 ARG A O   1 
ATOM 6508 C CB  . ARG A 1 840 ? 81.435  116.719 117.320 1.00 262.83 ? 840 ARG A CB  1 
ATOM 6509 C CG  . ARG A 1 840 ? 80.186  117.472 116.902 1.00 262.83 ? 840 ARG A CG  1 
ATOM 6510 C CD  . ARG A 1 840 ? 80.058  117.555 115.392 1.00 262.83 ? 840 ARG A CD  1 
ATOM 6511 N NE  . ARG A 1 840 ? 78.854  118.276 115.000 1.00 262.83 ? 840 ARG A NE  1 
ATOM 6512 C CZ  . ARG A 1 840 ? 77.646  117.735 114.938 1.00 262.83 ? 840 ARG A CZ  1 
ATOM 6513 N NH1 . ARG A 1 840 ? 77.444  116.459 115.226 1.00 262.83 ? 840 ARG A NH1 1 
ATOM 6514 N NH2 . ARG A 1 840 ? 76.613  118.494 114.584 1.00 262.83 ? 840 ARG A NH2 1 
ATOM 6515 N N   . PRO A 1 841 ? 82.953  114.999 120.201 1.00 267.64 ? 841 PRO A N   1 
ATOM 6516 C CA  . PRO A 1 841 ? 84.258  114.450 120.593 1.00 267.64 ? 841 PRO A CA  1 
ATOM 6517 C C   . PRO A 1 841 ? 84.795  113.384 119.653 1.00 267.64 ? 841 PRO A C   1 
ATOM 6518 O O   . PRO A 1 841 ? 85.978  113.034 119.761 1.00 267.64 ? 841 PRO A O   1 
ATOM 6519 C CB  . PRO A 1 841 ? 83.980  113.864 121.983 1.00 267.64 ? 841 PRO A CB  1 
ATOM 6520 C CG  . PRO A 1 841 ? 82.537  113.492 121.936 1.00 267.64 ? 841 PRO A CG  1 
ATOM 6521 C CD  . PRO A 1 841 ? 81.869  114.543 121.089 1.00 267.64 ? 841 PRO A CD  1 
ATOM 6522 N N   . MET A 1 842 ? 83.975  112.856 118.740 1.00 263.75 ? 842 MET A N   1 
ATOM 6523 C CA  . MET A 1 842 ? 84.443  111.803 117.845 1.00 263.75 ? 842 MET A CA  1 
ATOM 6524 C C   . MET A 1 842 ? 85.426  112.317 116.801 1.00 263.75 ? 842 MET A C   1 
ATOM 6525 O O   . MET A 1 842 ? 86.221  111.529 116.279 1.00 263.75 ? 842 MET A O   1 
ATOM 6526 C CB  . MET A 1 842 ? 83.256  111.125 117.158 1.00 263.75 ? 842 MET A CB  1 
ATOM 6527 C CG  . MET A 1 842 ? 82.230  112.088 116.594 1.00 263.75 ? 842 MET A CG  1 
ATOM 6528 S SD  . MET A 1 842 ? 81.351  112.972 117.894 1.00 263.75 ? 842 MET A SD  1 
ATOM 6529 C CE  . MET A 1 842 ? 80.617  111.611 118.797 1.00 263.75 ? 842 MET A CE  1 
ATOM 6530 N N   . ILE A 1 843 ? 85.391  113.612 116.475 1.00 262.06 ? 843 ILE A N   1 
ATOM 6531 C CA  . ILE A 1 843 ? 86.410  114.159 115.590 1.00 262.06 ? 843 ILE A CA  1 
ATOM 6532 C C   . ILE A 1 843 ? 87.753  114.253 116.299 1.00 262.06 ? 843 ILE A C   1 
ATOM 6533 O O   . ILE A 1 843 ? 88.801  114.203 115.644 1.00 262.06 ? 843 ILE A O   1 
ATOM 6534 C CB  . ILE A 1 843 ? 85.986  115.534 115.036 1.00 262.06 ? 843 ILE A CB  1 
ATOM 6535 C CG1 . ILE A 1 843 ? 85.893  116.567 116.159 1.00 262.06 ? 843 ILE A CG1 1 
ATOM 6536 C CG2 . ILE A 1 843 ? 84.662  115.424 114.292 1.00 262.06 ? 843 ILE A CG2 1 
ATOM 6537 C CD1 . ILE A 1 843 ? 85.534  117.956 115.684 1.00 262.06 ? 843 ILE A CD1 1 
ATOM 6538 N N   . HIS A 1 844 ? 87.750  114.392 117.627 1.00 267.22 ? 844 HIS A N   1 
ATOM 6539 C CA  . HIS A 1 844 ? 89.000  114.420 118.379 1.00 267.22 ? 844 HIS A CA  1 
ATOM 6540 C C   . HIS A 1 844 ? 89.723  113.080 118.296 1.00 267.22 ? 844 HIS A C   1 
ATOM 6541 O O   . HIS A 1 844 ? 90.947  113.034 118.132 1.00 267.22 ? 844 HIS A O   1 
ATOM 6542 C CB  . HIS A 1 844 ? 88.727  114.800 119.834 1.00 267.22 ? 844 HIS A CB  1 
ATOM 6543 C CG  . HIS A 1 844 ? 88.175  116.181 120.005 1.00 267.22 ? 844 HIS A CG  1 
ATOM 6544 N ND1 . HIS A 1 844 ? 88.205  117.123 119.000 1.00 267.22 ? 844 HIS A ND1 1 
ATOM 6545 C CD2 . HIS A 1 844 ? 87.578  116.778 121.063 1.00 267.22 ? 844 HIS A CD2 1 
ATOM 6546 C CE1 . HIS A 1 844 ? 87.652  118.242 119.431 1.00 267.22 ? 844 HIS A CE1 1 
ATOM 6547 N NE2 . HIS A 1 844 ? 87.262  118.060 120.680 1.00 267.22 ? 844 HIS A NE2 1 
ATOM 6548 N N   . GLU A 1 845 ? 88.984  111.975 118.421 1.00 271.56 ? 845 GLU A N   1 
ATOM 6549 C CA  . GLU A 1 845 ? 89.610  110.665 118.273 1.00 271.56 ? 845 GLU A CA  1 
ATOM 6550 C C   . GLU A 1 845 ? 89.905  110.350 116.811 1.00 271.56 ? 845 GLU A C   1 
ATOM 6551 O O   . GLU A 1 845 ? 90.787  109.534 116.520 1.00 271.56 ? 845 GLU A O   1 
ATOM 6552 C CB  . GLU A 1 845 ? 88.736  109.578 118.906 1.00 271.56 ? 845 GLU A CB  1 
ATOM 6553 C CG  . GLU A 1 845 ? 87.312  109.502 118.383 1.00 271.56 ? 845 GLU A CG  1 
ATOM 6554 C CD  . GLU A 1 845 ? 87.173  108.584 117.182 1.00 271.56 ? 845 GLU A CD  1 
ATOM 6555 O OE1 . GLU A 1 845 ? 88.135  107.846 116.882 1.00 271.56 ? 845 GLU A OE1 1 
ATOM 6556 O OE2 . GLU A 1 845 ? 86.100  108.598 116.542 1.00 271.56 ? 845 GLU A OE2 1 
ATOM 6557 N N   . LEU A 1 846 ? 89.177  110.974 115.880 1.00 259.10 ? 846 LEU A N   1 
ATOM 6558 C CA  . LEU A 1 846 ? 89.451  110.756 114.463 1.00 259.10 ? 846 LEU A CA  1 
ATOM 6559 C C   . LEU A 1 846 ? 90.739  111.452 114.035 1.00 259.10 ? 846 LEU A C   1 
ATOM 6560 O O   . LEU A 1 846 ? 91.393  111.027 113.076 1.00 259.10 ? 846 LEU A O   1 
ATOM 6561 C CB  . LEU A 1 846 ? 88.272  111.239 113.617 1.00 259.10 ? 846 LEU A CB  1 
ATOM 6562 C CG  . LEU A 1 846 ? 88.264  110.796 112.151 1.00 259.10 ? 846 LEU A CG  1 
ATOM 6563 C CD1 . LEU A 1 846 ? 88.058  109.291 112.043 1.00 259.10 ? 846 LEU A CD1 1 
ATOM 6564 C CD2 . LEU A 1 846 ? 87.203  111.547 111.361 1.00 259.10 ? 846 LEU A CD2 1 
ATOM 6565 N N   . LEU A 1 847 ? 91.113  112.533 114.723 1.00 258.61 ? 847 LEU A N   1 
ATOM 6566 C CA  . LEU A 1 847 ? 92.358  113.215 114.385 1.00 258.61 ? 847 LEU A CA  1 
ATOM 6567 C C   . LEU A 1 847 ? 93.557  112.614 115.109 1.00 258.61 ? 847 LEU A C   1 
ATOM 6568 O O   . LEU A 1 847 ? 94.680  112.690 114.600 1.00 258.61 ? 847 LEU A O   1 
ATOM 6569 C CB  . LEU A 1 847 ? 92.243  114.715 114.679 1.00 258.61 ? 847 LEU A CB  1 
ATOM 6570 C CG  . LEU A 1 847 ? 91.923  115.222 116.088 1.00 258.61 ? 847 LEU A CG  1 
ATOM 6571 C CD1 . LEU A 1 847 ? 93.182  115.388 116.931 1.00 258.61 ? 847 LEU A CD1 1 
ATOM 6572 C CD2 . LEU A 1 847 ? 91.145  116.529 116.020 1.00 258.61 ? 847 LEU A CD2 1 
ATOM 6573 N N   . THR A 1 848 ? 93.346  112.021 116.288 1.00 264.49 ? 848 THR A N   1 
ATOM 6574 C CA  . THR A 1 848 ? 94.444  111.354 116.982 1.00 264.49 ? 848 THR A CA  1 
ATOM 6575 C C   . THR A 1 848 ? 94.949  110.155 116.190 1.00 264.49 ? 848 THR A C   1 
ATOM 6576 O O   . THR A 1 848 ? 96.159  109.907 116.134 1.00 264.49 ? 848 THR A O   1 
ATOM 6577 C CB  . THR A 1 848 ? 94.010  110.923 118.384 1.00 264.49 ? 848 THR A CB  1 
ATOM 6578 O OG1 . THR A 1 848 ? 92.791  110.175 118.301 1.00 264.49 ? 848 THR A OG1 1 
ATOM 6579 C CG2 . THR A 1 848 ? 93.807  112.136 119.282 1.00 264.49 ? 848 THR A CG2 1 
ATOM 6580 N N   . GLU A 1 849 ? 94.039  109.394 115.576 1.00 260.71 ? 849 GLU A N   1 
ATOM 6581 C CA  . GLU A 1 849 ? 94.463  108.298 114.713 1.00 260.71 ? 849 GLU A CA  1 
ATOM 6582 C C   . GLU A 1 849 ? 95.086  108.800 113.417 1.00 260.71 ? 849 GLU A C   1 
ATOM 6583 O O   . GLU A 1 849 ? 95.684  108.006 112.684 1.00 260.71 ? 849 GLU A O   1 
ATOM 6584 C CB  . GLU A 1 849 ? 93.285  107.366 114.416 1.00 260.71 ? 849 GLU A CB  1 
ATOM 6585 C CG  . GLU A 1 849 ? 92.088  108.031 113.763 1.00 260.71 ? 849 GLU A CG  1 
ATOM 6586 C CD  . GLU A 1 849 ? 92.139  107.981 112.248 1.00 260.71 ? 849 GLU A CD  1 
ATOM 6587 O OE1 . GLU A 1 849 ? 93.018  107.281 111.702 1.00 260.71 ? 849 GLU A OE1 1 
ATOM 6588 O OE2 . GLU A 1 849 ? 91.296  108.639 111.605 1.00 260.71 ? 849 GLU A OE2 1 
ATOM 6589 N N   . GLY A 1 850 ? 94.951  110.094 113.116 1.00 263.17 ? 850 GLY A N   1 
ATOM 6590 C CA  . GLY A 1 850 ? 95.702  110.666 112.011 1.00 263.17 ? 850 GLY A CA  1 
ATOM 6591 C C   . GLY A 1 850 ? 97.199  110.578 112.235 1.00 263.17 ? 850 GLY A C   1 
ATOM 6592 O O   . GLY A 1 850 ? 97.968  110.388 111.288 1.00 263.17 ? 850 GLY A O   1 
ATOM 6593 N N   . ARG A 1 851 ? 97.634  110.721 113.490 1.00 261.54 ? 851 ARG A N   1 
ATOM 6594 C CA  . ARG A 1 851 ? 99.033  110.473 113.821 1.00 261.54 ? 851 ARG A CA  1 
ATOM 6595 C C   . ARG A 1 851 ? 99.398  109.017 113.565 1.00 261.54 ? 851 ARG A C   1 
ATOM 6596 O O   . ARG A 1 851 ? 100.509 108.714 113.116 1.00 261.54 ? 851 ARG A O   1 
ATOM 6597 C CB  . ARG A 1 851 ? 99.306  110.842 115.279 1.00 261.54 ? 851 ARG A CB  1 
ATOM 6598 C CG  . ARG A 1 851 ? 98.527  112.044 115.793 1.00 261.54 ? 851 ARG A CG  1 
ATOM 6599 C CD  . ARG A 1 851 ? 98.898  113.327 115.069 1.00 261.54 ? 851 ARG A CD  1 
ATOM 6600 N NE  . ARG A 1 851 ? 98.268  114.486 115.690 1.00 261.54 ? 851 ARG A NE  1 
ATOM 6601 C CZ  . ARG A 1 851 ? 97.056  114.933 115.389 1.00 261.54 ? 851 ARG A CZ  1 
ATOM 6602 N NH1 . ARG A 1 851 ? 96.314  114.349 114.464 1.00 261.54 ? 851 ARG A NH1 1 
ATOM 6603 N NH2 . ARG A 1 851 ? 96.576  115.990 116.037 1.00 261.54 ? 851 ARG A NH2 1 
ATOM 6604 N N   . ARG A 1 852 ? 98.473  108.099 113.857 1.00 267.84 ? 852 ARG A N   1 
ATOM 6605 C CA  . ARG A 1 852 ? 98.708  106.684 113.591 1.00 267.84 ? 852 ARG A CA  1 
ATOM 6606 C C   . ARG A 1 852 ? 98.836  106.404 112.099 1.00 267.84 ? 852 ARG A C   1 
ATOM 6607 O O   . ARG A 1 852 ? 99.613  105.529 111.700 1.00 267.84 ? 852 ARG A O   1 
ATOM 6608 C CB  . ARG A 1 852 ? 97.578  105.846 114.192 1.00 267.84 ? 852 ARG A CB  1 
ATOM 6609 C CG  . ARG A 1 852 ? 97.630  104.370 113.833 1.00 267.84 ? 852 ARG A CG  1 
ATOM 6610 C CD  . ARG A 1 852 ? 96.232  103.806 113.653 1.00 267.84 ? 852 ARG A CD  1 
ATOM 6611 N NE  . ARG A 1 852 ? 95.436  104.625 112.746 1.00 267.84 ? 852 ARG A NE  1 
ATOM 6612 C CZ  . ARG A 1 852 ? 95.475  104.534 111.424 1.00 267.84 ? 852 ARG A CZ  1 
ATOM 6613 N NH1 . ARG A 1 852 ? 96.265  103.666 110.813 1.00 267.84 ? 852 ARG A NH1 1 
ATOM 6614 N NH2 . ARG A 1 852 ? 94.703  105.336 110.696 1.00 267.84 ? 852 ARG A NH2 1 
ATOM 6615 N N   . SER A 1 853 ? 98.087  107.128 111.268 1.00 264.54 ? 853 SER A N   1 
ATOM 6616 C CA  . SER A 1 853 ? 98.099  106.887 109.831 1.00 264.54 ? 853 SER A CA  1 
ATOM 6617 C C   . SER A 1 853 ? 99.504  107.042 109.263 1.00 264.54 ? 853 SER A C   1 
ATOM 6618 O O   . SER A 1 853 ? 100.192 108.035 109.515 1.00 264.54 ? 853 SER A O   1 
ATOM 6619 C CB  . SER A 1 853 ? 97.140  107.846 109.126 1.00 264.54 ? 853 SER A CB  1 
ATOM 6620 O OG  . SER A 1 853 ? 95.805  107.642 109.558 1.00 264.54 ? 853 SER A OG  1 
ATOM 6621 N N   . LYS A 1 854 ? 99.925  106.046 108.483 1.00 252.24 ? 854 LYS A N   1 
ATOM 6622 C CA  . LYS A 1 854 ? 101.273 105.997 107.934 1.00 252.24 ? 854 LYS A CA  1 
ATOM 6623 C C   . LYS A 1 854 ? 101.480 106.934 106.750 1.00 252.24 ? 854 LYS A C   1 
ATOM 6624 O O   . LYS A 1 854 ? 102.622 107.330 106.493 1.00 252.24 ? 854 LYS A O   1 
ATOM 6625 C CB  . LYS A 1 854 ? 101.610 104.562 107.522 1.00 252.24 ? 854 LYS A CB  1 
ATOM 6626 C CG  . LYS A 1 854 ? 100.602 103.943 106.569 1.00 252.24 ? 854 LYS A CG  1 
ATOM 6627 C CD  . LYS A 1 854 ? 100.714 102.429 106.556 1.00 252.24 ? 854 LYS A CD  1 
ATOM 6628 C CE  . LYS A 1 854 ? 100.422 101.845 107.930 1.00 252.24 ? 854 LYS A CE  1 
ATOM 6629 N NZ  . LYS A 1 854 ? 99.074  102.241 108.427 1.00 252.24 ? 854 LYS A NZ  1 
ATOM 6630 N N   . THR A 1 855 ? 100.422 107.283 106.022 1.00 250.21 ? 855 THR A N   1 
ATOM 6631 C CA  . THR A 1 855 ? 100.563 108.147 104.858 1.00 250.21 ? 855 THR A CA  1 
ATOM 6632 C C   . THR A 1 855 ? 101.068 109.526 105.269 1.00 250.21 ? 855 THR A C   1 
ATOM 6633 O O   . THR A 1 855 ? 100.594 110.115 106.244 1.00 250.21 ? 855 THR A O   1 
ATOM 6634 C CB  . THR A 1 855 ? 99.228  108.273 104.124 1.00 250.21 ? 855 THR A CB  1 
ATOM 6635 O OG1 . THR A 1 855 ? 98.693  106.967 103.880 1.00 250.21 ? 855 THR A OG1 1 
ATOM 6636 C CG2 . THR A 1 855 ? 99.419  108.983 102.794 1.00 250.21 ? 855 THR A CG2 1 
ATOM 6637 N N   . ASN A 1 856 ? 102.048 110.035 104.517 1.00 250.72 ? 856 ASN A N   1 
ATOM 6638 C CA  . ASN A 1 856 ? 102.663 111.313 104.863 1.00 250.72 ? 856 ASN A CA  1 
ATOM 6639 C C   . ASN A 1 856 ? 101.669 112.463 104.754 1.00 250.72 ? 856 ASN A C   1 
ATOM 6640 O O   . ASN A 1 856 ? 101.652 113.356 105.609 1.00 250.72 ? 856 ASN A O   1 
ATOM 6641 C CB  . ASN A 1 856 ? 103.877 111.569 103.972 1.00 250.72 ? 856 ASN A CB  1 
ATOM 6642 C CG  . ASN A 1 856 ? 104.658 112.798 104.392 1.00 250.72 ? 856 ASN A CG  1 
ATOM 6643 O OD1 . ASN A 1 856 ? 104.598 113.226 105.545 1.00 250.72 ? 856 ASN A OD1 1 
ATOM 6644 N ND2 . ASN A 1 856 ? 105.398 113.374 103.453 1.00 250.72 ? 856 ASN A ND2 1 
ATOM 6645 N N   . LYS A 1 857 ? 100.837 112.465 103.707 1.00 240.73 ? 857 LYS A N   1 
ATOM 6646 C CA  . LYS A 1 857 ? 99.862  113.540 103.554 1.00 240.73 ? 857 LYS A CA  1 
ATOM 6647 C C   . LYS A 1 857 ? 98.854  113.542 104.696 1.00 240.73 ? 857 LYS A C   1 
ATOM 6648 O O   . LYS A 1 857 ? 98.340  114.605 105.064 1.00 240.73 ? 857 LYS A O   1 
ATOM 6649 C CB  . LYS A 1 857 ? 99.146  113.432 102.206 1.00 240.73 ? 857 LYS A CB  1 
ATOM 6650 C CG  . LYS A 1 857 ? 98.169  112.274 102.085 1.00 240.73 ? 857 LYS A CG  1 
ATOM 6651 C CD  . LYS A 1 857 ? 97.369  112.369 100.795 1.00 240.73 ? 857 LYS A CD  1 
ATOM 6652 C CE  . LYS A 1 857 ? 96.274  111.314 100.739 1.00 240.73 ? 857 LYS A CE  1 
ATOM 6653 N NZ  . LYS A 1 857 ? 96.820  109.932 100.667 1.00 240.73 ? 857 LYS A NZ  1 
ATOM 6654 N N   . ALA A 1 858 ? 98.558  112.370 105.263 1.00 243.86 ? 858 ALA A N   1 
ATOM 6655 C CA  . ALA A 1 858 ? 97.742  112.325 106.469 1.00 243.86 ? 858 ALA A CA  1 
ATOM 6656 C C   . ALA A 1 858 ? 98.437  113.041 107.619 1.00 243.86 ? 858 ALA A C   1 
ATOM 6657 O O   . ALA A 1 858 ? 97.801  113.789 108.370 1.00 243.86 ? 858 ALA A O   1 
ATOM 6658 C CB  . ALA A 1 858 ? 97.431  110.876 106.843 1.00 243.86 ? 858 ALA A CB  1 
ATOM 6659 N N   . LYS A 1 859 ? 99.749  112.827 107.766 1.00 251.46 ? 859 LYS A N   1 
ATOM 6660 C CA  . LYS A 1 859 ? 100.508 113.510 108.809 1.00 251.46 ? 859 LYS A CA  1 
ATOM 6661 C C   . LYS A 1 859 ? 100.482 115.021 108.616 1.00 251.46 ? 859 LYS A C   1 
ATOM 6662 O O   . LYS A 1 859 ? 100.272 115.770 109.577 1.00 251.46 ? 859 LYS A O   1 
ATOM 6663 C CB  . LYS A 1 859 ? 101.951 113.008 108.821 1.00 251.46 ? 859 LYS A CB  1 
ATOM 6664 C CG  . LYS A 1 859 ? 102.110 111.524 109.104 1.00 251.46 ? 859 LYS A CG  1 
ATOM 6665 C CD  . LYS A 1 859 ? 102.049 111.228 110.592 1.00 251.46 ? 859 LYS A CD  1 
ATOM 6666 C CE  . LYS A 1 859 ? 102.546 109.824 110.888 1.00 251.46 ? 859 LYS A CE  1 
ATOM 6667 N NZ  . LYS A 1 859 ? 102.576 109.547 112.350 1.00 251.46 ? 859 LYS A NZ  1 
ATOM 6668 N N   . THR A 1 860 ? 100.699 115.485 107.382 1.00 253.76 ? 860 THR A N   1 
ATOM 6669 C CA  . THR A 1 860 ? 100.719 116.921 107.116 1.00 253.76 ? 860 THR A CA  1 
ATOM 6670 C C   . THR A 1 860 ? 99.365  117.557 107.405 1.00 253.76 ? 860 THR A C   1 
ATOM 6671 O O   . THR A 1 860 ? 99.296  118.660 107.960 1.00 253.76 ? 860 THR A O   1 
ATOM 6672 C CB  . THR A 1 860 ? 101.133 117.184 105.669 1.00 253.76 ? 860 THR A CB  1 
ATOM 6673 O OG1 . THR A 1 860 ? 100.166 116.610 104.780 1.00 253.76 ? 860 THR A OG1 1 
ATOM 6674 C CG2 . THR A 1 860 ? 102.501 116.576 105.388 1.00 253.76 ? 860 THR A CG2 1 
ATOM 6675 N N   . LEU A 1 861 ? 98.278  116.887 107.023 1.00 246.36 ? 861 LEU A N   1 
ATOM 6676 C CA  . LEU A 1 861 ? 96.952  117.413 107.322 1.00 246.36 ? 861 LEU A CA  1 
ATOM 6677 C C   . LEU A 1 861 ? 96.597  117.233 108.793 1.00 246.36 ? 861 LEU A C   1 
ATOM 6678 O O   . LEU A 1 861 ? 95.833  118.033 109.345 1.00 246.36 ? 861 LEU A O   1 
ATOM 6679 C CB  . LEU A 1 861 ? 95.916  116.749 106.416 1.00 246.36 ? 861 LEU A CB  1 
ATOM 6680 C CG  . LEU A 1 861 ? 96.142  117.045 104.930 1.00 246.36 ? 861 LEU A CG  1 
ATOM 6681 C CD1 . LEU A 1 861 ? 95.207  116.235 104.049 1.00 246.36 ? 861 LEU A CD1 1 
ATOM 6682 C CD2 . LEU A 1 861 ? 95.986  118.535 104.652 1.00 246.36 ? 861 LEU A CD2 1 
ATOM 6683 N N   . ALA A 1 862 ? 97.135  116.196 109.441 1.00 253.76 ? 862 ALA A N   1 
ATOM 6684 C CA  . ALA A 1 862 ? 96.911  116.020 110.873 1.00 253.76 ? 862 ALA A CA  1 
ATOM 6685 C C   . ALA A 1 862 ? 97.545  117.152 111.672 1.00 253.76 ? 862 ALA A C   1 
ATOM 6686 O O   . ALA A 1 862 ? 96.900  117.745 112.545 1.00 253.76 ? 862 ALA A O   1 
ATOM 6687 C CB  . ALA A 1 862 ? 97.455  114.667 111.332 1.00 253.76 ? 862 ALA A CB  1 
ATOM 6688 N N   . ARG A 1 863 ? 98.815  117.462 111.393 1.00 256.89 ? 863 ARG A N   1 
ATOM 6689 C CA  . ARG A 1 863 ? 99.463  118.574 112.082 1.00 256.89 ? 863 ARG A CA  1 
ATOM 6690 C C   . ARG A 1 863 ? 98.832  119.906 111.703 1.00 256.89 ? 863 ARG A C   1 
ATOM 6691 O O   . ARG A 1 863 ? 98.790  120.826 112.527 1.00 256.89 ? 863 ARG A O   1 
ATOM 6692 C CB  . ARG A 1 863 ? 100.966 118.586 111.791 1.00 256.89 ? 863 ARG A CB  1 
ATOM 6693 C CG  . ARG A 1 863 ? 101.336 118.688 110.321 1.00 256.89 ? 863 ARG A CG  1 
ATOM 6694 C CD  . ARG A 1 863 ? 102.097 119.971 110.013 1.00 256.89 ? 863 ARG A CD  1 
ATOM 6695 N NE  . ARG A 1 863 ? 101.266 121.159 110.165 1.00 256.89 ? 863 ARG A NE  1 
ATOM 6696 C CZ  . ARG A 1 863 ? 101.666 122.393 109.889 1.00 256.89 ? 863 ARG A CZ  1 
ATOM 6697 N NH1 . ARG A 1 863 ? 102.886 122.641 109.441 1.00 256.89 ? 863 ARG A NH1 1 
ATOM 6698 N NH2 . ARG A 1 863 ? 100.820 123.404 110.067 1.00 256.89 ? 863 ARG A NH2 1 
ATOM 6699 N N   . TRP A 1 864 ? 98.343  120.030 110.466 1.00 249.06 ? 864 TRP A N   1 
ATOM 6700 C CA  . TRP A 1 864 ? 97.621  121.234 110.069 1.00 249.06 ? 864 TRP A CA  1 
ATOM 6701 C C   . TRP A 1 864 ? 96.336  121.393 110.871 1.00 249.06 ? 864 TRP A C   1 
ATOM 6702 O O   . TRP A 1 864 ? 95.970  122.509 111.258 1.00 249.06 ? 864 TRP A O   1 
ATOM 6703 C CB  . TRP A 1 864 ? 97.323  121.193 108.570 1.00 249.06 ? 864 TRP A CB  1 
ATOM 6704 C CG  . TRP A 1 864 ? 96.510  122.352 108.076 1.00 249.06 ? 864 TRP A CG  1 
ATOM 6705 C CD1 . TRP A 1 864 ? 95.158  122.389 107.899 1.00 249.06 ? 864 TRP A CD1 1 
ATOM 6706 C CD2 . TRP A 1 864 ? 97.000  123.642 107.689 1.00 249.06 ? 864 TRP A CD2 1 
ATOM 6707 N NE1 . TRP A 1 864 ? 94.775  123.622 107.428 1.00 249.06 ? 864 TRP A NE1 1 
ATOM 6708 C CE2 . TRP A 1 864 ? 95.888  124.409 107.291 1.00 249.06 ? 864 TRP A CE2 1 
ATOM 6709 C CE3 . TRP A 1 864 ? 98.271  124.222 107.641 1.00 249.06 ? 864 TRP A CE3 1 
ATOM 6710 C CZ2 . TRP A 1 864 ? 96.007  125.726 106.853 1.00 249.06 ? 864 TRP A CZ2 1 
ATOM 6711 C CZ3 . TRP A 1 864 ? 98.388  125.531 107.208 1.00 249.06 ? 864 TRP A CZ3 1 
ATOM 6712 C CH2 . TRP A 1 864 ? 97.263  126.267 106.818 1.00 249.06 ? 864 TRP A CH2 1 
ATOM 6713 N N   . ALA A 1 865 ? 95.633  120.287 111.123 1.00 253.93 ? 865 ALA A N   1 
ATOM 6714 C CA  . ALA A 1 865 ? 94.385  120.356 111.875 1.00 253.93 ? 865 ALA A CA  1 
ATOM 6715 C C   . ALA A 1 865 ? 94.624  120.756 113.326 1.00 253.93 ? 865 ALA A C   1 
ATOM 6716 O O   . ALA A 1 865 ? 93.911  121.611 113.865 1.00 253.93 ? 865 ALA A O   1 
ATOM 6717 C CB  . ALA A 1 865 ? 93.657  119.014 111.804 1.00 253.93 ? 865 ALA A CB  1 
ATOM 6718 N N   . THR A 1 866 ? 95.619  120.150 113.979 1.00 256.43 ? 866 THR A N   1 
ATOM 6719 C CA  . THR A 1 866 ? 95.831  120.402 115.400 1.00 256.43 ? 866 THR A CA  1 
ATOM 6720 C C   . THR A 1 866 ? 96.482  121.756 115.667 1.00 256.43 ? 866 THR A C   1 
ATOM 6721 O O   . THR A 1 866 ? 96.222  122.360 116.713 1.00 256.43 ? 866 THR A O   1 
ATOM 6722 C CB  . THR A 1 866 ? 96.669  119.283 116.024 1.00 256.43 ? 866 THR A CB  1 
ATOM 6723 O OG1 . THR A 1 866 ? 96.829  119.528 117.428 1.00 256.43 ? 866 THR A OG1 1 
ATOM 6724 C CG2 . THR A 1 866 ? 98.040  119.193 115.371 1.00 256.43 ? 866 THR A CG2 1 
ATOM 6725 N N   . LYS A 1 867 ? 97.328  122.246 114.756 1.00 260.67 ? 867 LYS A N   1 
ATOM 6726 C CA  . LYS A 1 867 ? 97.964  123.542 114.979 1.00 260.67 ? 867 LYS A CA  1 
ATOM 6727 C C   . LYS A 1 867 ? 96.941  124.671 114.981 1.00 260.67 ? 867 LYS A C   1 
ATOM 6728 O O   . LYS A 1 867 ? 97.057  125.609 115.777 1.00 260.67 ? 867 LYS A O   1 
ATOM 6729 C CB  . LYS A 1 867 ? 99.055  123.793 113.931 1.00 260.67 ? 867 LYS A CB  1 
ATOM 6730 C CG  . LYS A 1 867 ? 98.566  123.973 112.497 1.00 260.67 ? 867 LYS A CG  1 
ATOM 6731 C CD  . LYS A 1 867 ? 98.451  125.445 112.119 1.00 260.67 ? 867 LYS A CD  1 
ATOM 6732 C CE  . LYS A 1 867 ? 97.735  125.616 110.790 1.00 260.67 ? 867 LYS A CE  1 
ATOM 6733 N NZ  . LYS A 1 867 ? 97.567  127.049 110.424 1.00 260.67 ? 867 LYS A NZ  1 
ATOM 6734 N N   . GLU A 1 868 ? 95.939  124.600 114.102 1.00 261.28 ? 868 GLU A N   1 
ATOM 6735 C CA  . GLU A 1 868 ? 94.914  125.636 114.068 1.00 261.28 ? 868 GLU A CA  1 
ATOM 6736 C C   . GLU A 1 868 ? 93.916  125.469 115.206 1.00 261.28 ? 868 GLU A C   1 
ATOM 6737 O O   . GLU A 1 868 ? 93.342  126.459 115.673 1.00 261.28 ? 868 GLU A O   1 
ATOM 6738 C CB  . GLU A 1 868 ? 94.206  125.624 112.715 1.00 261.28 ? 868 GLU A CB  1 
ATOM 6739 C CG  . GLU A 1 868 ? 93.707  126.986 112.269 1.00 261.28 ? 868 GLU A CG  1 
ATOM 6740 C CD  . GLU A 1 868 ? 93.528  127.073 110.766 1.00 261.28 ? 868 GLU A CD  1 
ATOM 6741 O OE1 . GLU A 1 868 ? 93.920  126.118 110.064 1.00 261.28 ? 868 GLU A OE1 1 
ATOM 6742 O OE2 . GLU A 1 868 ? 92.999  128.098 110.288 1.00 261.28 ? 868 GLU A OE2 1 
ATOM 6743 N N   . LEU A 1 869 ? 93.695  124.232 115.661 1.00 256.52 ? 869 LEU A N   1 
ATOM 6744 C CA  . LEU A 1 869 ? 92.838  124.011 116.821 1.00 256.52 ? 869 LEU A CA  1 
ATOM 6745 C C   . LEU A 1 869 ? 93.409  124.689 118.060 1.00 256.52 ? 869 LEU A C   1 
ATOM 6746 O O   . LEU A 1 869 ? 92.663  125.280 118.850 1.00 256.52 ? 869 LEU A O   1 
ATOM 6747 C CB  . LEU A 1 869 ? 92.657  122.513 117.067 1.00 256.52 ? 869 LEU A CB  1 
ATOM 6748 C CG  . LEU A 1 869 ? 91.272  121.925 116.783 1.00 256.52 ? 869 LEU A CG  1 
ATOM 6749 C CD1 . LEU A 1 869 ? 90.207  122.627 117.614 1.00 256.52 ? 869 LEU A CD1 1 
ATOM 6750 C CD2 . LEU A 1 869 ? 90.941  122.005 115.303 1.00 256.52 ? 869 LEU A CD2 1 
ATOM 6751 N N   . ARG A 1 870 ? 94.728  124.610 118.247 1.00 266.53 ? 870 ARG A N   1 
ATOM 6752 C CA  . ARG A 1 870 ? 95.362  125.310 119.358 1.00 266.53 ? 870 ARG A CA  1 
ATOM 6753 C C   . ARG A 1 870 ? 95.209  126.820 119.228 1.00 266.53 ? 870 ARG A C   1 
ATOM 6754 O O   . ARG A 1 870 ? 94.973  127.504 120.230 1.00 266.53 ? 870 ARG A O   1 
ATOM 6755 C CB  . ARG A 1 870 ? 96.841  124.935 119.445 1.00 266.53 ? 870 ARG A CB  1 
ATOM 6756 C CG  . ARG A 1 870 ? 97.097  123.447 119.612 1.00 266.53 ? 870 ARG A CG  1 
ATOM 6757 C CD  . ARG A 1 870 ? 96.391  122.899 120.840 1.00 266.53 ? 870 ARG A CD  1 
ATOM 6758 N NE  . ARG A 1 870 ? 96.602  121.465 120.994 1.00 266.53 ? 870 ARG A NE  1 
ATOM 6759 C CZ  . ARG A 1 870 ? 95.821  120.531 120.468 1.00 266.53 ? 870 ARG A CZ  1 
ATOM 6760 N NH1 . ARG A 1 870 ? 94.759  120.845 119.745 1.00 266.53 ? 870 ARG A NH1 1 
ATOM 6761 N NH2 . ARG A 1 870 ? 96.113  119.250 120.673 1.00 266.53 ? 870 ARG A NH2 1 
ATOM 6762 N N   . LYS A 1 871 ? 95.343  127.354 118.012 1.00 265.78 ? 871 LYS A N   1 
ATOM 6763 C CA  . LYS A 1 871 ? 95.196  128.793 117.814 1.00 265.78 ? 871 LYS A CA  1 
ATOM 6764 C C   . LYS A 1 871 ? 93.784  129.257 118.149 1.00 265.78 ? 871 LYS A C   1 
ATOM 6765 O O   . LYS A 1 871 ? 93.602  130.336 118.724 1.00 265.78 ? 871 LYS A O   1 
ATOM 6766 C CB  . LYS A 1 871 ? 95.562  129.169 116.378 1.00 265.78 ? 871 LYS A CB  1 
ATOM 6767 C CG  . LYS A 1 871 ? 97.024  128.932 116.029 1.00 265.78 ? 871 LYS A CG  1 
ATOM 6768 C CD  . LYS A 1 871 ? 97.381  129.533 114.678 1.00 265.78 ? 871 LYS A CD  1 
ATOM 6769 C CE  . LYS A 1 871 ? 96.538  128.937 113.565 1.00 265.78 ? 871 LYS A CE  1 
ATOM 6770 N NZ  . LYS A 1 871 ? 96.886  129.507 112.234 1.00 265.78 ? 871 LYS A NZ  1 
ATOM 6771 N N   . LEU A 1 872 ? 92.771  128.463 117.790 1.00 265.34 ? 872 LEU A N   1 
ATOM 6772 C CA  . LEU A 1 872 ? 91.401  128.819 118.145 1.00 265.34 ? 872 LEU A CA  1 
ATOM 6773 C C   . LEU A 1 872 ? 91.211  128.841 119.656 1.00 265.34 ? 872 LEU A C   1 
ATOM 6774 O O   . LEU A 1 872 ? 90.585  129.760 120.196 1.00 265.34 ? 872 LEU A O   1 
ATOM 6775 C CB  . LEU A 1 872 ? 90.414  127.847 117.500 1.00 265.34 ? 872 LEU A CB  1 
ATOM 6776 C CG  . LEU A 1 872 ? 90.423  127.718 115.977 1.00 265.34 ? 872 LEU A CG  1 
ATOM 6777 C CD1 . LEU A 1 872 ? 89.122  127.093 115.504 1.00 265.34 ? 872 LEU A CD1 1 
ATOM 6778 C CD2 . LEU A 1 872 ? 90.663  129.061 115.303 1.00 265.34 ? 872 LEU A CD2 1 
ATOM 6779 N N   . LYS A 1 873 ? 91.742  127.835 120.355 1.00 264.35 ? 873 LYS A N   1 
ATOM 6780 C CA  . LYS A 1 873 ? 91.670  127.833 121.812 1.00 264.35 ? 873 LYS A CA  1 
ATOM 6781 C C   . LYS A 1 873 ? 92.481  128.973 122.412 1.00 264.35 ? 873 LYS A C   1 
ATOM 6782 O O   . LYS A 1 873 ? 92.079  129.550 123.430 1.00 264.35 ? 873 LYS A O   1 
ATOM 6783 C CB  . LYS A 1 873 ? 92.145  126.488 122.363 1.00 264.35 ? 873 LYS A CB  1 
ATOM 6784 C CG  . LYS A 1 873 ? 91.231  125.323 122.016 1.00 264.35 ? 873 LYS A CG  1 
ATOM 6785 C CD  . LYS A 1 873 ? 91.647  124.054 122.743 1.00 264.35 ? 873 LYS A CD  1 
ATOM 6786 C CE  . LYS A 1 873 ? 93.017  123.577 122.291 1.00 264.35 ? 873 LYS A CE  1 
ATOM 6787 N NZ  . LYS A 1 873 ? 93.023  123.199 120.851 1.00 264.35 ? 873 LYS A NZ  1 
ATOM 6788 N N   . ASN A 1 874 ? 93.616  129.311 121.804 1.00 267.29 ? 874 ASN A N   1 
ATOM 6789 C CA  . ASN A 1 874 ? 94.443  130.423 122.248 1.00 267.29 ? 874 ASN A CA  1 
ATOM 6790 C C   . ASN A 1 874 ? 94.000  131.757 121.659 1.00 267.29 ? 874 ASN A C   1 
ATOM 6791 O O   . ASN A 1 874 ? 94.623  132.784 121.947 1.00 267.29 ? 874 ASN A O   1 
ATOM 6792 C CB  . ASN A 1 874 ? 95.910  130.162 121.897 1.00 267.29 ? 874 ASN A CB  1 
ATOM 6793 C CG  . ASN A 1 874 ? 96.448  128.901 122.543 1.00 267.29 ? 874 ASN A CG  1 
ATOM 6794 O OD1 . ASN A 1 874 ? 96.012  128.508 123.626 1.00 267.29 ? 874 ASN A OD1 1 
ATOM 6795 N ND2 . ASN A 1 874 ? 97.400  128.257 121.879 1.00 267.29 ? 874 ASN A ND2 1 
ATOM 6796 N N   . GLN A 1 875 ? 92.947  131.763 120.836 1.00 264.64 ? 875 GLN A N   1 
ATOM 6797 C CA  . GLN A 1 875 ? 92.448  133.016 120.277 1.00 264.64 ? 875 GLN A CA  1 
ATOM 6798 C C   . GLN A 1 875 ? 91.948  133.950 121.372 1.00 264.64 ? 875 GLN A C   1 
ATOM 6799 O O   . GLN A 1 875 ? 92.214  135.157 121.336 1.00 264.64 ? 875 GLN A O   1 
ATOM 6800 C CB  . GLN A 1 875 ? 91.337  132.732 119.265 1.00 264.64 ? 875 GLN A CB  1 
ATOM 6801 C CG  . GLN A 1 875 ? 90.700  133.977 118.665 1.00 264.64 ? 875 GLN A CG  1 
ATOM 6802 C CD  . GLN A 1 875 ? 89.524  133.653 117.762 1.00 264.64 ? 875 GLN A CD  1 
ATOM 6803 O OE1 . GLN A 1 875 ? 89.120  132.496 117.640 1.00 264.64 ? 875 GLN A OE1 1 
ATOM 6804 N NE2 . GLN A 1 875 ? 88.969  134.676 117.125 1.00 264.64 ? 875 GLN A NE2 1 
ATOM 6805 N N   . ALA A 1 876 ? 91.227  133.413 122.350 1.00 254.36 ? 876 ALA A N   1 
ATOM 6806 C CA  . ALA A 1 876 ? 90.721  134.215 123.458 1.00 254.36 ? 876 ALA A CA  1 
ATOM 6807 C C   . ALA A 1 876 ? 91.610  134.058 124.687 1.00 254.36 ? 876 ALA A C   1 
ATOM 6808 O O   . ALA A 1 876 ? 92.364  133.092 124.803 1.00 254.36 ? 876 ALA A O   1 
ATOM 6809 C CB  . ALA A 1 876 ? 89.287  133.825 123.784 1.00 254.36 ? 876 ALA A CB  1 
ATOM 6810 O OXT . ALA A 1 876 ? 91.595  134.893 125.591 0.00 254.36 ? 876 ALA A OXT 1 
ATOM 6811 N N   . ALA B 2 1   ? 89.008  78.279  85.423  1.00 160.45 ? 11  ALA B N   1 
ATOM 6812 C CA  . ALA B 2 1   ? 89.236  78.169  83.987  1.00 160.45 ? 11  ALA B CA  1 
ATOM 6813 C C   . ALA B 2 1   ? 90.720  77.988  83.679  1.00 160.45 ? 11  ALA B C   1 
ATOM 6814 O O   . ALA B 2 1   ? 91.364  77.080  84.205  1.00 160.45 ? 11  ALA B O   1 
ATOM 6815 C CB  . ALA B 2 1   ? 88.690  79.394  83.271  1.00 160.45 ? 11  ALA B CB  1 
ATOM 6816 N N   . ALA B 2 2   ? 91.251  78.851  82.817  1.00 146.46 ? 12  ALA B N   1 
ATOM 6817 C CA  . ALA B 2 2   ? 92.649  78.801  82.408  1.00 146.46 ? 12  ALA B CA  1 
ATOM 6818 C C   . ALA B 2 2   ? 93.397  79.988  83.004  1.00 146.46 ? 12  ALA B C   1 
ATOM 6819 O O   . ALA B 2 2   ? 92.919  81.126  82.941  1.00 146.46 ? 12  ALA B O   1 
ATOM 6820 C CB  . ALA B 2 2   ? 92.772  78.800  80.884  1.00 146.46 ? 12  ALA B CB  1 
ATOM 6821 N N   . ARG B 2 3   ? 94.569  79.719  83.578  1.00 140.95 ? 13  ARG B N   1 
ATOM 6822 C CA  . ARG B 2 3   ? 95.437  80.746  84.154  1.00 140.95 ? 13  ARG B CA  1 
ATOM 6823 C C   . ARG B 2 3   ? 96.579  81.110  83.213  1.00 140.95 ? 13  ARG B C   1 
ATOM 6824 O O   . ARG B 2 3   ? 97.702  81.373  83.651  1.00 140.95 ? 13  ARG B O   1 
ATOM 6825 C CB  . ARG B 2 3   ? 95.978  80.290  85.505  1.00 140.95 ? 13  ARG B CB  1 
ATOM 6826 C CG  . ARG B 2 3   ? 96.677  78.945  85.480  1.00 140.95 ? 13  ARG B CG  1 
ATOM 6827 C CD  . ARG B 2 3   ? 97.449  78.723  86.765  1.00 140.95 ? 13  ARG B CD  1 
ATOM 6828 N NE  . ARG B 2 3   ? 96.627  78.986  87.940  1.00 140.95 ? 13  ARG B NE  1 
ATOM 6829 C CZ  . ARG B 2 3   ? 97.098  79.080  89.175  1.00 140.95 ? 13  ARG B CZ  1 
ATOM 6830 N NH1 . ARG B 2 3   ? 98.387  78.935  89.436  1.00 140.95 ? 13  ARG B NH1 1 
ATOM 6831 N NH2 . ARG B 2 3   ? 96.256  79.333  90.173  1.00 140.95 ? 13  ARG B NH2 1 
ATOM 6832 N N   . LEU B 2 4   ? 96.302  81.132  81.907  1.00 134.75 ? 14  LEU B N   1 
ATOM 6833 C CA  . LEU B 2 4   ? 97.326  81.362  80.891  1.00 134.75 ? 14  LEU B CA  1 
ATOM 6834 C C   . LEU B 2 4   ? 97.995  82.730  81.012  1.00 134.75 ? 14  LEU B C   1 
ATOM 6835 O O   . LEU B 2 4   ? 98.939  83.014  80.266  1.00 134.75 ? 14  LEU B O   1 
ATOM 6836 C CB  . LEU B 2 4   ? 96.701  81.194  79.502  1.00 134.75 ? 14  LEU B CB  1 
ATOM 6837 C CG  . LEU B 2 4   ? 97.587  81.177  78.253  1.00 134.75 ? 14  LEU B CG  1 
ATOM 6838 C CD1 . LEU B 2 4   ? 98.613  80.057  78.302  1.00 134.75 ? 14  LEU B CD1 1 
ATOM 6839 C CD2 . LEU B 2 4   ? 96.729  81.067  77.004  1.00 134.75 ? 14  LEU B CD2 1 
ATOM 6840 N N   . HIS B 2 5   ? 97.554  83.577  81.942  1.00 140.34 ? 15  HIS B N   1 
ATOM 6841 C CA  . HIS B 2 5   ? 98.146  84.903  82.077  1.00 140.34 ? 15  HIS B CA  1 
ATOM 6842 C C   . HIS B 2 5   ? 99.421  84.902  82.914  1.00 140.34 ? 15  HIS B C   1 
ATOM 6843 O O   . HIS B 2 5   ? 99.800  85.958  83.434  1.00 140.34 ? 15  HIS B O   1 
ATOM 6844 C CB  . HIS B 2 5   ? 97.131  85.872  82.692  1.00 140.34 ? 15  HIS B CB  1 
ATOM 6845 C CG  . HIS B 2 5   ? 95.941  86.143  81.822  1.00 140.34 ? 15  HIS B CG  1 
ATOM 6846 N ND1 . HIS B 2 5   ? 95.738  85.512  80.613  1.00 140.34 ? 15  HIS B ND1 1 
ATOM 6847 C CD2 . HIS B 2 5   ? 94.891  86.983  81.988  1.00 140.34 ? 15  HIS B CD2 1 
ATOM 6848 C CE1 . HIS B 2 5   ? 94.614  85.950  80.073  1.00 140.34 ? 15  HIS B CE1 1 
ATOM 6849 N NE2 . HIS B 2 5   ? 94.081  86.843  80.887  1.00 140.34 ? 15  HIS B NE2 1 
ATOM 6850 N N   . ARG B 2 6   ? 100.091 83.759  83.053  1.00 133.49 ? 16  ARG B N   1 
ATOM 6851 C CA  . ARG B 2 6   ? 101.350 83.671  83.777  1.00 133.49 ? 16  ARG B CA  1 
ATOM 6852 C C   . ARG B 2 6   ? 102.450 82.992  82.973  1.00 133.49 ? 16  ARG B C   1 
ATOM 6853 O O   . ARG B 2 6   ? 103.515 82.707  83.530  1.00 133.49 ? 16  ARG B O   1 
ATOM 6854 C CB  . ARG B 2 6   ? 101.152 82.922  85.101  1.00 133.49 ? 16  ARG B CB  1 
ATOM 6855 C CG  . ARG B 2 6   ? 100.183 83.586  86.066  1.00 133.49 ? 16  ARG B CG  1 
ATOM 6856 C CD  . ARG B 2 6   ? 100.726 84.905  86.588  1.00 133.49 ? 16  ARG B CD  1 
ATOM 6857 N NE  . ARG B 2 6   ? 101.917 84.727  87.409  1.00 133.49 ? 16  ARG B NE  1 
ATOM 6858 C CZ  . ARG B 2 6   ? 101.902 84.545  88.723  1.00 133.49 ? 16  ARG B CZ  1 
ATOM 6859 N NH1 . ARG B 2 6   ? 100.767 84.503  89.401  1.00 133.49 ? 16  ARG B NH1 1 
ATOM 6860 N NH2 . ARG B 2 6   ? 103.054 84.397  89.371  1.00 133.49 ? 16  ARG B NH2 1 
ATOM 6861 N N   . PHE B 2 7   ? 102.226 82.721  81.687  1.00 127.76 ? 17  PHE B N   1 
ATOM 6862 C CA  . PHE B 2 7   ? 103.201 82.017  80.853  1.00 127.76 ? 17  PHE B CA  1 
ATOM 6863 C C   . PHE B 2 7   ? 104.094 83.042  80.166  1.00 127.76 ? 17  PHE B C   1 
ATOM 6864 O O   . PHE B 2 7   ? 103.761 83.556  79.095  1.00 127.76 ? 17  PHE B O   1 
ATOM 6865 C CB  . PHE B 2 7   ? 102.500 81.122  79.838  1.00 127.76 ? 17  PHE B CB  1 
ATOM 6866 C CG  . PHE B 2 7   ? 103.442 80.328  78.974  1.00 127.76 ? 17  PHE B CG  1 
ATOM 6867 C CD1 . PHE B 2 7   ? 104.477 79.600  79.541  1.00 127.76 ? 17  PHE B CD1 1 
ATOM 6868 C CD2 . PHE B 2 7   ? 103.283 80.295  77.598  1.00 127.76 ? 17  PHE B CD2 1 
ATOM 6869 C CE1 . PHE B 2 7   ? 105.341 78.862  78.750  1.00 127.76 ? 17  PHE B CE1 1 
ATOM 6870 C CE2 . PHE B 2 7   ? 104.144 79.559  76.803  1.00 127.76 ? 17  PHE B CE2 1 
ATOM 6871 C CZ  . PHE B 2 7   ? 105.174 78.843  77.379  1.00 127.76 ? 17  PHE B CZ  1 
ATOM 6872 N N   . LYS B 2 8   ? 105.237 83.332  80.789  1.00 122.32 ? 18  LYS B N   1 
ATOM 6873 C CA  . LYS B 2 8   ? 106.262 84.236  80.253  1.00 122.32 ? 18  LYS B CA  1 
ATOM 6874 C C   . LYS B 2 8   ? 105.639 85.613  80.057  1.00 122.32 ? 18  LYS B C   1 
ATOM 6875 O O   . LYS B 2 8   ? 105.478 86.342  81.051  1.00 122.32 ? 18  LYS B O   1 
ATOM 6876 C CB  . LYS B 2 8   ? 106.886 83.607  79.006  1.00 122.32 ? 18  LYS B CB  1 
ATOM 6877 C CG  . LYS B 2 8   ? 107.662 82.331  79.273  1.00 122.32 ? 18  LYS B CG  1 
ATOM 6878 C CD  . LYS B 2 8   ? 108.747 82.131  78.231  1.00 122.32 ? 18  LYS B CD  1 
ATOM 6879 C CE  . LYS B 2 8   ? 108.182 82.130  76.819  1.00 122.32 ? 18  LYS B CE  1 
ATOM 6880 N NZ  . LYS B 2 8   ? 107.552 80.829  76.460  1.00 122.32 ? 18  LYS B NZ  1 
ATOM 6881 N N   . ASN B 2 9   ? 105.282 86.014  78.839  1.00 123.33 ? 19  ASN B N   1 
ATOM 6882 C CA  . ASN B 2 9   ? 104.760 87.344  78.555  1.00 123.33 ? 19  ASN B CA  1 
ATOM 6883 C C   . ASN B 2 9   ? 103.529 87.278  77.660  1.00 123.33 ? 19  ASN B C   1 
ATOM 6884 O O   . ASN B 2 9   ? 103.359 88.087  76.745  1.00 123.33 ? 19  ASN B O   1 
ATOM 6885 C CB  . ASN B 2 9   ? 105.833 88.226  77.917  1.00 123.33 ? 19  ASN B CB  1 
ATOM 6886 C CG  . ASN B 2 9   ? 106.878 88.683  78.911  1.00 123.33 ? 19  ASN B CG  1 
ATOM 6887 O OD1 . ASN B 2 9   ? 106.582 88.883  80.088  1.00 123.33 ? 19  ASN B OD1 1 
ATOM 6888 N ND2 . ASN B 2 9   ? 108.108 88.856  78.442  1.00 123.33 ? 19  ASN B ND2 1 
ATOM 6889 N N   . LYS B 2 10  ? 102.651 86.308  77.906  1.00 129.17 ? 20  LYS B N   1 
ATOM 6890 C CA  . LYS B 2 10  ? 101.376 86.243  77.205  1.00 129.17 ? 20  LYS B CA  1 
ATOM 6891 C C   . LYS B 2 10  ? 100.256 86.933  77.973  1.00 129.17 ? 20  LYS B C   1 
ATOM 6892 O O   . LYS B 2 10  ? 99.139  87.039  77.457  1.00 129.17 ? 20  LYS B O   1 
ATOM 6893 C CB  . LYS B 2 10  ? 100.996 84.786  76.919  1.00 129.17 ? 20  LYS B CB  1 
ATOM 6894 C CG  . LYS B 2 10  ? 100.021 84.630  75.758  1.00 129.17 ? 20  LYS B CG  1 
ATOM 6895 C CD  . LYS B 2 10  ? 99.643  83.181  75.508  1.00 129.17 ? 20  LYS B CD  1 
ATOM 6896 C CE  . LYS B 2 10  ? 98.637  83.080  74.370  1.00 129.17 ? 20  LYS B CE  1 
ATOM 6897 N NZ  . LYS B 2 10  ? 98.258  81.675  74.066  1.00 129.17 ? 20  LYS B NZ  1 
ATOM 6898 N N   . GLY B 2 11  ? 100.533 87.418  79.180  1.00 142.80 ? 21  GLY B N   1 
ATOM 6899 C CA  . GLY B 2 11  ? 99.540  88.131  79.957  1.00 142.80 ? 21  GLY B CA  1 
ATOM 6900 C C   . GLY B 2 11  ? 99.712  89.632  79.863  1.00 142.80 ? 21  GLY B C   1 
ATOM 6901 O O   . GLY B 2 11  ? 99.485  90.357  80.836  1.00 142.80 ? 21  GLY B O   1 
ATOM 6902 N N   . LYS B 2 12  ? 100.110 90.107  78.685  1.00 136.16 ? 22  LYS B N   1 
ATOM 6903 C CA  . LYS B 2 12  ? 100.327 91.529  78.423  1.00 136.16 ? 22  LYS B CA  1 
ATOM 6904 C C   . LYS B 2 12  ? 99.558  91.868  77.150  1.00 136.16 ? 22  LYS B C   1 
ATOM 6905 O O   . LYS B 2 12  ? 100.116 91.824  76.050  1.00 136.16 ? 22  LYS B O   1 
ATOM 6906 C CB  . LYS B 2 12  ? 101.813 91.845  78.275  1.00 136.16 ? 22  LYS B CB  1 
ATOM 6907 C CG  . LYS B 2 12  ? 102.694 91.263  79.373  1.00 136.16 ? 22  LYS B CG  1 
ATOM 6908 C CD  . LYS B 2 12  ? 102.535 92.017  80.681  1.00 136.16 ? 22  LYS B CD  1 
ATOM 6909 C CE  . LYS B 2 12  ? 103.374 93.286  80.695  1.00 136.16 ? 22  LYS B CE  1 
ATOM 6910 N NZ  . LYS B 2 12  ? 104.835 92.982  80.715  1.00 136.16 ? 22  LYS B NZ  1 
ATOM 6911 N N   . ASP B 2 13  ? 98.283  92.201  77.302  1.00 160.79 ? 23  ASP B N   1 
ATOM 6912 C CA  . ASP B 2 13  ? 97.390  92.464  76.185  1.00 160.79 ? 23  ASP B CA  1 
ATOM 6913 C C   . ASP B 2 13  ? 97.186  93.967  76.027  1.00 160.79 ? 23  ASP B C   1 
ATOM 6914 O O   . ASP B 2 13  ? 97.619  94.771  76.857  1.00 160.79 ? 23  ASP B O   1 
ATOM 6915 C CB  . ASP B 2 13  ? 96.055  91.744  76.387  1.00 160.79 ? 23  ASP B CB  1 
ATOM 6916 C CG  . ASP B 2 13  ? 96.215  90.244  76.518  1.00 160.79 ? 23  ASP B CG  1 
ATOM 6917 O OD1 . ASP B 2 13  ? 97.364  89.758  76.461  1.00 160.79 ? 23  ASP B OD1 1 
ATOM 6918 O OD2 . ASP B 2 13  ? 95.191  89.549  76.678  1.00 160.79 ? 23  ASP B OD2 1 
ATOM 6919 N N   . SER B 2 14  ? 96.517  94.340  74.934  1.00 167.33 ? 24  SER B N   1 
ATOM 6920 C CA  . SER B 2 14  ? 96.230  95.749  74.685  1.00 167.33 ? 24  SER B CA  1 
ATOM 6921 C C   . SER B 2 14  ? 95.337  96.334  75.772  1.00 167.33 ? 24  SER B C   1 
ATOM 6922 O O   . SER B 2 14  ? 95.585  97.444  76.257  1.00 167.33 ? 24  SER B O   1 
ATOM 6923 C CB  . SER B 2 14  ? 95.585  95.915  73.309  1.00 167.33 ? 24  SER B CB  1 
ATOM 6924 O OG  . SER B 2 14  ? 96.422  95.395  72.290  1.00 167.33 ? 24  SER B OG  1 
ATOM 6925 N N   . THR B 2 15  ? 94.285  95.607  76.159  1.00 167.83 ? 25  THR B N   1 
ATOM 6926 C CA  . THR B 2 15  ? 93.409  96.083  77.225  1.00 167.83 ? 25  THR B CA  1 
ATOM 6927 C C   . THR B 2 15  ? 94.120  96.116  78.572  1.00 167.83 ? 25  THR B C   1 
ATOM 6928 O O   . THR B 2 15  ? 93.895  97.037  79.364  1.00 167.83 ? 25  THR B O   1 
ATOM 6929 C CB  . THR B 2 15  ? 92.157  95.212  77.310  1.00 167.83 ? 25  THR B CB  1 
ATOM 6930 O OG1 . THR B 2 15  ? 92.532  93.858  77.591  1.00 167.83 ? 25  THR B OG1 1 
ATOM 6931 C CG2 . THR B 2 15  ? 91.388  95.261  75.998  1.00 167.83 ? 25  THR B CG2 1 
ATOM 6932 N N   . GLU B 2 16  ? 94.966  95.122  78.854  1.00 157.15 ? 26  GLU B N   1 
ATOM 6933 C CA  . GLU B 2 16  ? 95.671  95.094  80.133  1.00 157.15 ? 26  GLU B CA  1 
ATOM 6934 C C   . GLU B 2 16  ? 96.583  96.304  80.293  1.00 157.15 ? 26  GLU B C   1 
ATOM 6935 O O   . GLU B 2 16  ? 96.632  96.913  81.367  1.00 157.15 ? 26  GLU B O   1 
ATOM 6936 C CB  . GLU B 2 16  ? 96.468  93.796  80.263  1.00 157.15 ? 26  GLU B CB  1 
ATOM 6937 C CG  . GLU B 2 16  ? 97.537  93.820  81.346  1.00 157.15 ? 26  GLU B CG  1 
ATOM 6938 C CD  . GLU B 2 16  ? 96.963  93.945  82.743  1.00 157.15 ? 26  GLU B CD  1 
ATOM 6939 O OE1 . GLU B 2 16  ? 95.795  93.557  82.952  1.00 157.15 ? 26  GLU B OE1 1 
ATOM 6940 O OE2 . GLU B 2 16  ? 97.686  94.431  83.637  1.00 157.15 ? 26  GLU B OE2 1 
ATOM 6941 N N   . MET B 2 17  ? 97.310  96.670  79.236  1.00 158.35 ? 27  MET B N   1 
ATOM 6942 C CA  . MET B 2 17  ? 98.199  97.824  79.317  1.00 158.35 ? 27  MET B CA  1 
ATOM 6943 C C   . MET B 2 17  ? 97.423  99.128  79.462  1.00 158.35 ? 27  MET B C   1 
ATOM 6944 O O   . MET B 2 17  ? 97.957  100.107 79.995  1.00 158.35 ? 27  MET B O   1 
ATOM 6945 C CB  . MET B 2 17  ? 99.106  97.874  78.089  1.00 158.35 ? 27  MET B CB  1 
ATOM 6946 C CG  . MET B 2 17  ? 100.024 96.669  77.951  1.00 158.35 ? 27  MET B CG  1 
ATOM 6947 S SD  . MET B 2 17  ? 101.123 96.457  79.363  1.00 158.35 ? 27  MET B SD  1 
ATOM 6948 C CE  . MET B 2 17  ? 102.030 98.000  79.306  1.00 158.35 ? 27  MET B CE  1 
ATOM 6949 N N   . ARG B 2 18  ? 96.176  99.166  78.982  1.00 153.07 ? 28  ARG B N   1 
ATOM 6950 C CA  . ARG B 2 18  ? 95.377  100.384 79.080  1.00 153.07 ? 28  ARG B CA  1 
ATOM 6951 C C   . ARG B 2 18  ? 95.140  100.787 80.532  1.00 153.07 ? 28  ARG B C   1 
ATOM 6952 O O   . ARG B 2 18  ? 95.313  101.958 80.891  1.00 153.07 ? 28  ARG B O   1 
ATOM 6953 C CB  . ARG B 2 18  ? 94.044  100.196 78.355  1.00 153.07 ? 28  ARG B CB  1 
ATOM 6954 C CG  . ARG B 2 18  ? 94.083  100.510 76.870  1.00 153.07 ? 28  ARG B CG  1 
ATOM 6955 C CD  . ARG B 2 18  ? 94.080  102.009 76.634  1.00 153.07 ? 28  ARG B CD  1 
ATOM 6956 N NE  . ARG B 2 18  ? 92.967  102.651 77.321  1.00 153.07 ? 28  ARG B NE  1 
ATOM 6957 C CZ  . ARG B 2 18  ? 91.734  102.729 76.839  1.00 153.07 ? 28  ARG B CZ  1 
ATOM 6958 N NH1 . ARG B 2 18  ? 91.419  102.215 75.661  1.00 153.07 ? 28  ARG B NH1 1 
ATOM 6959 N NH2 . ARG B 2 18  ? 90.793  103.336 77.557  1.00 153.07 ? 28  ARG B NH2 1 
ATOM 6960 N N   . ARG B 2 19  ? 94.743  99.836  81.382  1.00 154.86 ? 29  ARG B N   1 
ATOM 6961 C CA  . ARG B 2 19  ? 94.460  100.178 82.772  1.00 154.86 ? 29  ARG B CA  1 
ATOM 6962 C C   . ARG B 2 19  ? 95.729  100.532 83.536  1.00 154.86 ? 29  ARG B C   1 
ATOM 6963 O O   . ARG B 2 19  ? 95.674  101.304 84.500  1.00 154.86 ? 29  ARG B O   1 
ATOM 6964 C CB  . ARG B 2 19  ? 93.722  99.032  83.469  1.00 154.86 ? 29  ARG B CB  1 
ATOM 6965 C CG  . ARG B 2 19  ? 94.528  97.754  83.624  1.00 154.86 ? 29  ARG B CG  1 
ATOM 6966 C CD  . ARG B 2 19  ? 93.958  96.877  84.728  1.00 154.86 ? 29  ARG B CD  1 
ATOM 6967 N NE  . ARG B 2 19  ? 94.024  97.536  86.027  1.00 154.86 ? 29  ARG B NE  1 
ATOM 6968 C CZ  . ARG B 2 19  ? 95.092  97.537  86.813  1.00 154.86 ? 29  ARG B CZ  1 
ATOM 6969 N NH1 . ARG B 2 19  ? 96.207  96.916  86.465  1.00 154.86 ? 29  ARG B NH1 1 
ATOM 6970 N NH2 . ARG B 2 19  ? 95.041  98.180  87.977  1.00 154.86 ? 29  ARG B NH2 1 
ATOM 6971 N N   . ARG B 2 20  ? 96.873  99.974  83.133  1.00 150.21 ? 30  ARG B N   1 
ATOM 6972 C CA  . ARG B 2 20  ? 98.129  100.294 83.804  1.00 150.21 ? 30  ARG B CA  1 
ATOM 6973 C C   . ARG B 2 20  ? 98.545  101.736 83.541  1.00 150.21 ? 30  ARG B C   1 
ATOM 6974 O O   . ARG B 2 20  ? 99.118  102.394 84.416  1.00 150.21 ? 30  ARG B O   1 
ATOM 6975 C CB  . ARG B 2 20  ? 99.223  99.329  83.352  1.00 150.21 ? 30  ARG B CB  1 
ATOM 6976 C CG  . ARG B 2 20  ? 98.867  97.862  83.529  1.00 150.21 ? 30  ARG B CG  1 
ATOM 6977 C CD  . ARG B 2 20  ? 99.854  96.958  82.807  1.00 150.21 ? 30  ARG B CD  1 
ATOM 6978 N NE  . ARG B 2 20  ? 101.193 97.039  83.378  1.00 150.21 ? 30  ARG B NE  1 
ATOM 6979 C CZ  . ARG B 2 20  ? 101.667 96.210  84.297  1.00 150.21 ? 30  ARG B CZ  1 
ATOM 6980 N NH1 . ARG B 2 20  ? 100.937 95.212  84.769  1.00 150.21 ? 30  ARG B NH1 1 
ATOM 6981 N NH2 . ARG B 2 20  ? 102.903 96.386  84.755  1.00 150.21 ? 30  ARG B NH2 1 
ATOM 6982 N N   . ARG B 2 21  ? 98.279  102.237 82.332  1.00 148.82 ? 31  ARG B N   1 
ATOM 6983 C CA  . ARG B 2 21  ? 98.689  103.593 81.979  1.00 148.82 ? 31  ARG B CA  1 
ATOM 6984 C C   . ARG B 2 21  ? 97.829  104.637 82.682  1.00 148.82 ? 31  ARG B C   1 
ATOM 6985 O O   . ARG B 2 21  ? 98.347  105.638 83.191  1.00 148.82 ? 31  ARG B O   1 
ATOM 6986 C CB  . ARG B 2 21  ? 98.627  103.776 80.461  1.00 148.82 ? 31  ARG B CB  1 
ATOM 6987 C CG  . ARG B 2 21  ? 99.625  104.784 79.906  1.00 148.82 ? 31  ARG B CG  1 
ATOM 6988 C CD  . ARG B 2 21  ? 99.475  104.968 78.399  1.00 148.82 ? 31  ARG B CD  1 
ATOM 6989 N NE  . ARG B 2 21  ? 99.728  103.742 77.650  1.00 148.82 ? 31  ARG B NE  1 
ATOM 6990 C CZ  . ARG B 2 21  ? 98.781  102.965 77.142  1.00 148.82 ? 31  ARG B CZ  1 
ATOM 6991 N NH1 . ARG B 2 21  ? 97.496  103.253 77.292  1.00 148.82 ? 31  ARG B NH1 1 
ATOM 6992 N NH2 . ARG B 2 21  ? 99.133  101.872 76.466  1.00 148.82 ? 31  ARG B NH2 1 
ATOM 6993 N N   . ILE B 2 22  ? 96.509  104.426 82.711  1.00 152.10 ? 32  ILE B N   1 
ATOM 6994 C CA  . ILE B 2 22  ? 95.606  105.432 83.265  1.00 152.10 ? 32  ILE B CA  1 
ATOM 6995 C C   . ILE B 2 22  ? 95.805  105.597 84.768  1.00 152.10 ? 32  ILE B C   1 
ATOM 6996 O O   . ILE B 2 22  ? 95.721  106.717 85.288  1.00 152.10 ? 32  ILE B O   1 
ATOM 6997 C CB  . ILE B 2 22  ? 94.142  105.092 82.924  1.00 152.10 ? 32  ILE B CB  1 
ATOM 6998 C CG1 . ILE B 2 22  ? 93.787  103.680 83.388  1.00 152.10 ? 32  ILE B CG1 1 
ATOM 6999 C CG2 . ILE B 2 22  ? 93.895  105.237 81.430  1.00 152.10 ? 32  ILE B CG2 1 
ATOM 7000 C CD1 . ILE B 2 22  ? 92.353  103.296 83.114  1.00 152.10 ? 32  ILE B CD1 1 
ATOM 7001 N N   . GLU B 2 23  ? 96.053  104.505 85.496  1.00 168.53 ? 33  GLU B N   1 
ATOM 7002 C CA  . GLU B 2 23  ? 96.271  104.630 86.934  1.00 168.53 ? 33  GLU B CA  1 
ATOM 7003 C C   . GLU B 2 23  ? 97.532  105.427 87.241  1.00 168.53 ? 33  GLU B C   1 
ATOM 7004 O O   . GLU B 2 23  ? 97.611  106.079 88.287  1.00 168.53 ? 33  GLU B O   1 
ATOM 7005 C CB  . GLU B 2 23  ? 96.328  103.250 87.592  1.00 168.53 ? 33  GLU B CB  1 
ATOM 7006 C CG  . GLU B 2 23  ? 97.412  102.329 87.060  1.00 168.53 ? 33  GLU B CG  1 
ATOM 7007 C CD  . GLU B 2 23  ? 98.700  102.410 87.858  1.00 168.53 ? 33  GLU B CD  1 
ATOM 7008 O OE1 . GLU B 2 23  ? 98.709  103.077 88.914  1.00 168.53 ? 33  GLU B OE1 1 
ATOM 7009 O OE2 . GLU B 2 23  ? 99.704  101.802 87.428  1.00 168.53 ? 33  GLU B OE2 1 
ATOM 7010 N N   . VAL B 2 24  ? 98.528  105.380 86.355  1.00 162.79 ? 34  VAL B N   1 
ATOM 7011 C CA  . VAL B 2 24  ? 99.705  106.225 86.526  1.00 162.79 ? 34  VAL B CA  1 
ATOM 7012 C C   . VAL B 2 24  ? 99.343  107.690 86.315  1.00 162.79 ? 34  VAL B C   1 
ATOM 7013 O O   . VAL B 2 24  ? 99.765  108.565 87.081  1.00 162.79 ? 34  VAL B O   1 
ATOM 7014 C CB  . VAL B 2 24  ? 100.829 105.771 85.578  1.00 162.79 ? 34  VAL B CB  1 
ATOM 7015 C CG1 . VAL B 2 24  ? 102.004 106.737 85.639  1.00 162.79 ? 34  VAL B CG1 1 
ATOM 7016 C CG2 . VAL B 2 24  ? 101.277 104.364 85.935  1.00 162.79 ? 34  VAL B CG2 1 
ATOM 7017 N N   . ASN B 2 25  ? 98.549  107.979 85.282  1.00 167.61 ? 35  ASN B N   1 
ATOM 7018 C CA  . ASN B 2 25  ? 98.198  109.361 84.975  1.00 167.61 ? 35  ASN B CA  1 
ATOM 7019 C C   . ASN B 2 25  ? 97.400  110.003 86.104  1.00 167.61 ? 35  ASN B C   1 
ATOM 7020 O O   . ASN B 2 25  ? 97.660  111.154 86.475  1.00 167.61 ? 35  ASN B O   1 
ATOM 7021 C CB  . ASN B 2 25  ? 97.413  109.421 83.666  1.00 167.61 ? 35  ASN B CB  1 
ATOM 7022 C CG  . ASN B 2 25  ? 97.132  110.841 83.221  1.00 167.61 ? 35  ASN B CG  1 
ATOM 7023 O OD1 . ASN B 2 25  ? 97.844  111.773 83.594  1.00 167.61 ? 35  ASN B OD1 1 
ATOM 7024 N ND2 . ASN B 2 25  ? 96.088  111.013 82.419  1.00 167.61 ? 35  ASN B ND2 1 
ATOM 7025 N N   . VAL B 2 26  ? 96.426  109.279 86.663  1.00 163.27 ? 36  VAL B N   1 
ATOM 7026 C CA  . VAL B 2 26  ? 95.597  109.851 87.721  1.00 163.27 ? 36  VAL B CA  1 
ATOM 7027 C C   . VAL B 2 26  ? 96.426  110.125 88.972  1.00 163.27 ? 36  VAL B C   1 
ATOM 7028 O O   . VAL B 2 26  ? 96.189  111.116 89.673  1.00 163.27 ? 36  VAL B O   1 
ATOM 7029 C CB  . VAL B 2 26  ? 94.388  108.940 88.018  1.00 163.27 ? 36  VAL B CB  1 
ATOM 7030 C CG1 . VAL B 2 26  ? 94.831  107.596 88.569  1.00 163.27 ? 36  VAL B CG1 1 
ATOM 7031 C CG2 . VAL B 2 26  ? 93.423  109.624 88.976  1.00 163.27 ? 36  VAL B CG2 1 
ATOM 7032 N N   . GLU B 2 27  ? 97.404  109.266 89.276  1.00 174.67 ? 37  GLU B N   1 
ATOM 7033 C CA  . GLU B 2 27  ? 98.298  109.540 90.396  1.00 174.67 ? 37  GLU B CA  1 
ATOM 7034 C C   . GLU B 2 27  ? 99.116  110.800 90.148  1.00 174.67 ? 37  GLU B C   1 
ATOM 7035 O O   . GLU B 2 27  ? 99.312  111.610 91.061  1.00 174.67 ? 37  GLU B O   1 
ATOM 7036 C CB  . GLU B 2 27  ? 99.213  108.344 90.650  1.00 174.67 ? 37  GLU B CB  1 
ATOM 7037 C CG  . GLU B 2 27  ? 98.490  107.101 91.142  1.00 174.67 ? 37  GLU B CG  1 
ATOM 7038 C CD  . GLU B 2 27  ? 97.834  107.297 92.495  1.00 174.67 ? 37  GLU B CD  1 
ATOM 7039 O OE1 . GLU B 2 27  ? 98.355  108.095 93.303  1.00 174.67 ? 37  GLU B OE1 1 
ATOM 7040 O OE2 . GLU B 2 27  ? 96.794  106.654 92.752  1.00 174.67 ? 37  GLU B OE2 1 
ATOM 7041 N N   . LEU B 2 28  ? 99.607  110.979 88.918  1.00 171.93 ? 38  LEU B N   1 
ATOM 7042 C CA  . LEU B 2 28  ? 100.269 112.230 88.564  1.00 171.93 ? 38  LEU B CA  1 
ATOM 7043 C C   . LEU B 2 28  ? 99.312  113.407 88.693  1.00 171.93 ? 38  LEU B C   1 
ATOM 7044 O O   . LEU B 2 28  ? 99.698  114.480 89.172  1.00 171.93 ? 38  LEU B O   1 
ATOM 7045 C CB  . LEU B 2 28  ? 100.835 112.147 87.147  1.00 171.93 ? 38  LEU B CB  1 
ATOM 7046 C CG  . LEU B 2 28  ? 102.304 111.732 87.018  1.00 171.93 ? 38  LEU B CG  1 
ATOM 7047 C CD1 . LEU B 2 28  ? 103.200 112.694 87.784  1.00 171.93 ? 38  LEU B CD1 1 
ATOM 7048 C CD2 . LEU B 2 28  ? 102.523 110.303 87.490  1.00 171.93 ? 38  LEU B CD2 1 
ATOM 7049 N N   . ARG B 2 29  ? 98.060  113.225 88.266  1.00 162.32 ? 39  ARG B N   1 
ATOM 7050 C CA  . ARG B 2 29  ? 97.039  114.233 88.523  1.00 162.32 ? 39  ARG B CA  1 
ATOM 7051 C C   . ARG B 2 29  ? 96.861  114.453 90.019  1.00 162.32 ? 39  ARG B C   1 
ATOM 7052 O O   . ARG B 2 29  ? 96.758  115.596 90.480  1.00 162.32 ? 39  ARG B O   1 
ATOM 7053 C CB  . ARG B 2 29  ? 95.716  113.813 87.884  1.00 162.32 ? 39  ARG B CB  1 
ATOM 7054 C CG  . ARG B 2 29  ? 94.612  114.850 87.995  1.00 162.32 ? 39  ARG B CG  1 
ATOM 7055 C CD  . ARG B 2 29  ? 93.242  114.220 87.796  1.00 162.32 ? 39  ARG B CD  1 
ATOM 7056 N NE  . ARG B 2 29  ? 93.194  113.363 86.618  1.00 162.32 ? 39  ARG B NE  1 
ATOM 7057 C CZ  . ARG B 2 29  ? 92.820  113.765 85.411  1.00 162.32 ? 39  ARG B CZ  1 
ATOM 7058 N NH1 . ARG B 2 29  ? 92.449  115.014 85.182  1.00 162.32 ? 39  ARG B NH1 1 
ATOM 7059 N NH2 . ARG B 2 29  ? 92.823  112.892 84.407  1.00 162.32 ? 39  ARG B NH2 1 
ATOM 7060 N N   . LYS B 2 30  ? 96.817  113.366 90.792  1.00 175.75 ? 40  LYS B N   1 
ATOM 7061 C CA  . LYS B 2 30  ? 96.782  113.488 92.245  1.00 175.75 ? 40  LYS B CA  1 
ATOM 7062 C C   . LYS B 2 30  ? 98.044  114.159 92.770  1.00 175.75 ? 40  LYS B C   1 
ATOM 7063 O O   . LYS B 2 30  ? 97.972  115.067 93.606  1.00 175.75 ? 40  LYS B O   1 
ATOM 7064 C CB  . LYS B 2 30  ? 96.602  112.107 92.879  1.00 175.75 ? 40  LYS B CB  1 
ATOM 7065 C CG  . LYS B 2 30  ? 97.165  111.966 94.288  1.00 175.75 ? 40  LYS B CG  1 
ATOM 7066 C CD  . LYS B 2 30  ? 96.326  112.705 95.318  1.00 175.75 ? 40  LYS B CD  1 
ATOM 7067 C CE  . LYS B 2 30  ? 96.917  112.554 96.712  1.00 175.75 ? 40  LYS B CE  1 
ATOM 7068 N NZ  . LYS B 2 30  ? 96.137  113.307 97.733  1.00 175.75 ? 40  LYS B NZ  1 
ATOM 7069 N N   . ALA B 2 31  ? 99.211  113.732 92.282  1.00 178.18 ? 41  ALA B N   1 
ATOM 7070 C CA  . ALA B 2 31  ? 100.466 114.299 92.765  1.00 178.18 ? 41  ALA B CA  1 
ATOM 7071 C C   . ALA B 2 31  ? 100.572 115.780 92.428  1.00 178.18 ? 41  ALA B C   1 
ATOM 7072 O O   . ALA B 2 31  ? 100.994 116.583 93.267  1.00 178.18 ? 41  ALA B O   1 
ATOM 7073 C CB  . ALA B 2 31  ? 101.651 113.528 92.184  1.00 178.18 ? 41  ALA B CB  1 
ATOM 7074 N N   . LYS B 2 32  ? 100.195 116.161 91.205  1.00 178.78 ? 42  LYS B N   1 
ATOM 7075 C CA  . LYS B 2 32  ? 100.257 117.567 90.822  1.00 178.78 ? 42  LYS B CA  1 
ATOM 7076 C C   . LYS B 2 32  ? 99.274  118.402 91.633  1.00 178.78 ? 42  LYS B C   1 
ATOM 7077 O O   . LYS B 2 32  ? 99.527  119.583 91.901  1.00 178.78 ? 42  LYS B O   1 
ATOM 7078 C CB  . LYS B 2 32  ? 99.986  117.714 89.324  1.00 178.78 ? 42  LYS B CB  1 
ATOM 7079 C CG  . LYS B 2 32  ? 100.234 119.110 88.776  1.00 178.78 ? 42  LYS B CG  1 
ATOM 7080 C CD  . LYS B 2 32  ? 101.695 119.511 88.917  1.00 178.78 ? 42  LYS B CD  1 
ATOM 7081 C CE  . LYS B 2 32  ? 102.608 118.574 88.141  1.00 178.78 ? 42  LYS B CE  1 
ATOM 7082 N NZ  . LYS B 2 32  ? 102.301 118.571 86.684  1.00 178.78 ? 42  LYS B NZ  1 
ATOM 7083 N N   . LYS B 2 33  ? 98.146  117.808 92.027  1.00 177.62 ? 43  LYS B N   1 
ATOM 7084 C CA  . LYS B 2 33  ? 97.159  118.537 92.815  1.00 177.62 ? 43  LYS B CA  1 
ATOM 7085 C C   . LYS B 2 33  ? 97.712  118.916 94.184  1.00 177.62 ? 43  LYS B C   1 
ATOM 7086 O O   . LYS B 2 33  ? 97.709  120.094 94.560  1.00 177.62 ? 43  LYS B O   1 
ATOM 7087 C CB  . LYS B 2 33  ? 95.887  117.702 92.963  1.00 177.62 ? 43  LYS B CB  1 
ATOM 7088 C CG  . LYS B 2 33  ? 94.791  118.391 93.755  1.00 177.62 ? 43  LYS B CG  1 
ATOM 7089 C CD  . LYS B 2 33  ? 93.602  117.471 93.985  1.00 177.62 ? 43  LYS B CD  1 
ATOM 7090 C CE  . LYS B 2 33  ? 93.004  116.988 92.672  1.00 177.62 ? 43  LYS B CE  1 
ATOM 7091 N NZ  . LYS B 2 33  ? 92.531  118.117 91.822  1.00 177.62 ? 43  LYS B NZ  1 
ATOM 7092 N N   . ASP B 2 34  ? 98.182  117.928 94.951  1.00 194.75 ? 44  ASP B N   1 
ATOM 7093 C CA  . ASP B 2 34  ? 98.694  118.220 96.286  1.00 194.75 ? 44  ASP B CA  1 
ATOM 7094 C C   . ASP B 2 34  ? 99.967  119.055 96.235  1.00 194.75 ? 44  ASP B C   1 
ATOM 7095 O O   . ASP B 2 34  ? 100.144 119.955 97.063  1.00 194.75 ? 44  ASP B O   1 
ATOM 7096 C CB  . ASP B 2 34  ? 98.931  116.926 97.069  1.00 194.75 ? 44  ASP B CB  1 
ATOM 7097 C CG  . ASP B 2 34  ? 99.844  115.956 96.346  1.00 194.75 ? 44  ASP B CG  1 
ATOM 7098 O OD1 . ASP B 2 34  ? 101.035 116.279 96.148  1.00 194.75 ? 44  ASP B OD1 1 
ATOM 7099 O OD2 . ASP B 2 34  ? 99.373  114.857 95.988  1.00 194.75 ? 44  ASP B OD2 1 
ATOM 7100 N N   . ASP B 2 35  ? 100.861 118.774 95.281  1.00 210.24 ? 45  ASP B N   1 
ATOM 7101 C CA  . ASP B 2 35  ? 102.099 119.542 95.183  1.00 210.24 ? 45  ASP B CA  1 
ATOM 7102 C C   . ASP B 2 35  ? 101.813 121.015 94.917  1.00 210.24 ? 45  ASP B C   1 
ATOM 7103 O O   . ASP B 2 35  ? 102.431 121.893 95.529  1.00 210.24 ? 45  ASP B O   1 
ATOM 7104 C CB  . ASP B 2 35  ? 102.995 118.958 94.090  1.00 210.24 ? 45  ASP B CB  1 
ATOM 7105 C CG  . ASP B 2 35  ? 104.413 119.504 94.140  1.00 210.24 ? 45  ASP B CG  1 
ATOM 7106 O OD1 . ASP B 2 35  ? 104.746 120.224 95.105  1.00 210.24 ? 45  ASP B OD1 1 
ATOM 7107 O OD2 . ASP B 2 35  ? 105.196 119.213 93.211  1.00 210.24 ? 45  ASP B OD2 1 
ATOM 7108 N N   . GLN B 2 36  ? 100.875 121.304 94.011  1.00 201.09 ? 46  GLN B N   1 
ATOM 7109 C CA  . GLN B 2 36  ? 100.438 122.682 93.812  1.00 201.09 ? 46  GLN B CA  1 
ATOM 7110 C C   . GLN B 2 36  ? 99.792  123.239 95.074  1.00 201.09 ? 46  GLN B C   1 
ATOM 7111 O O   . GLN B 2 36  ? 100.021 124.399 95.437  1.00 201.09 ? 46  GLN B O   1 
ATOM 7112 C CB  . GLN B 2 36  ? 99.466  122.756 92.633  1.00 201.09 ? 46  GLN B CB  1 
ATOM 7113 C CG  . GLN B 2 36  ? 98.832  124.122 92.412  1.00 201.09 ? 46  GLN B CG  1 
ATOM 7114 C CD  . GLN B 2 36  ? 97.751  124.092 91.348  1.00 201.09 ? 46  GLN B CD  1 
ATOM 7115 O OE1 . GLN B 2 36  ? 97.559  123.081 90.672  1.00 201.09 ? 46  GLN B OE1 1 
ATOM 7116 N NE2 . GLN B 2 36  ? 97.035  125.200 91.197  1.00 201.09 ? 46  GLN B NE2 1 
ATOM 7117 N N   . MET B 2 37  ? 98.979  122.427 95.751  1.00 202.44 ? 47  MET B N   1 
ATOM 7118 C CA  . MET B 2 37  ? 98.289  122.889 96.950  1.00 202.44 ? 47  MET B CA  1 
ATOM 7119 C C   . MET B 2 37  ? 99.250  123.043 98.125  1.00 202.44 ? 47  MET B C   1 
ATOM 7120 O O   . MET B 2 37  ? 99.183  124.035 98.860  1.00 202.44 ? 47  MET B O   1 
ATOM 7121 C CB  . MET B 2 37  ? 97.154  121.923 97.296  1.00 202.44 ? 47  MET B CB  1 
ATOM 7122 C CG  . MET B 2 37  ? 96.069  122.497 98.198  1.00 202.44 ? 47  MET B CG  1 
ATOM 7123 S SD  . MET B 2 37  ? 96.524  122.543 99.942  1.00 202.44 ? 47  MET B SD  1 
ATOM 7124 C CE  . MET B 2 37  ? 97.045  120.848 100.196 1.00 202.44 ? 47  MET B CE  1 
ATOM 7125 N N   . LEU B 2 38  ? 100.142 122.069 98.326  1.00 218.60 ? 48  LEU B N   1 
ATOM 7126 C CA  . LEU B 2 38  ? 101.031 122.108 99.485  1.00 218.60 ? 48  LEU B CA  1 
ATOM 7127 C C   . LEU B 2 38  ? 101.976 123.303 99.429  1.00 218.60 ? 48  LEU B C   1 
ATOM 7128 O O   . LEU B 2 38  ? 102.227 123.948 100.454 1.00 218.60 ? 48  LEU B O   1 
ATOM 7129 C CB  . LEU B 2 38  ? 101.822 120.804 99.590  1.00 218.60 ? 48  LEU B CB  1 
ATOM 7130 C CG  . LEU B 2 38  ? 102.748 120.660 100.801 1.00 218.60 ? 48  LEU B CG  1 
ATOM 7131 C CD1 . LEU B 2 38  ? 101.974 120.846 102.097 1.00 218.60 ? 48  LEU B CD1 1 
ATOM 7132 C CD2 . LEU B 2 38  ? 103.452 119.311 100.784 1.00 218.60 ? 48  LEU B CD2 1 
ATOM 7133 N N   . LYS B 2 39  ? 102.515 123.612 98.246  1.00 220.48 ? 49  LYS B N   1 
ATOM 7134 C CA  . LYS B 2 39  ? 103.448 124.729 98.129  1.00 220.48 ? 49  LYS B CA  1 
ATOM 7135 C C   . LYS B 2 39  ? 102.787 126.060 98.469  1.00 220.48 ? 49  LYS B C   1 
ATOM 7136 O O   . LYS B 2 39  ? 103.442 126.951 99.022  1.00 220.48 ? 49  LYS B O   1 
ATOM 7137 C CB  . LYS B 2 39  ? 104.049 124.773 96.723  1.00 220.48 ? 49  LYS B CB  1 
ATOM 7138 C CG  . LYS B 2 39  ? 105.005 123.627 96.427  1.00 220.48 ? 49  LYS B CG  1 
ATOM 7139 C CD  . LYS B 2 39  ? 105.672 123.787 95.069  1.00 220.48 ? 49  LYS B CD  1 
ATOM 7140 C CE  . LYS B 2 39  ? 104.651 123.788 93.944  1.00 220.48 ? 49  LYS B CE  1 
ATOM 7141 N NZ  . LYS B 2 39  ? 105.303 123.881 92.608  1.00 220.48 ? 49  LYS B NZ  1 
ATOM 7142 N N   . ARG B 2 40  ? 101.504 126.219 98.140  1.00 216.25 ? 50  ARG B N   1 
ATOM 7143 C CA  . ARG B 2 40  ? 100.781 127.431 98.505  1.00 216.25 ? 50  ARG B CA  1 
ATOM 7144 C C   . ARG B 2 40  ? 100.412 127.471 99.983  1.00 216.25 ? 50  ARG B C   1 
ATOM 7145 O O   . ARG B 2 40  ? 100.200 128.561 100.525 1.00 216.25 ? 50  ARG B O   1 
ATOM 7146 C CB  . ARG B 2 40  ? 99.518  127.571 97.647  1.00 216.25 ? 50  ARG B CB  1 
ATOM 7147 C CG  . ARG B 2 40  ? 98.250  127.036 98.298  1.00 216.25 ? 50  ARG B CG  1 
ATOM 7148 C CD  . ARG B 2 40  ? 97.163  126.737 97.275  1.00 216.25 ? 50  ARG B CD  1 
ATOM 7149 N NE  . ARG B 2 40  ? 96.670  127.932 96.600  1.00 216.25 ? 50  ARG B NE  1 
ATOM 7150 C CZ  . ARG B 2 40  ? 95.689  127.932 95.709  1.00 216.25 ? 50  ARG B CZ  1 
ATOM 7151 N NH1 . ARG B 2 40  ? 95.070  126.815 95.362  1.00 216.25 ? 50  ARG B NH1 1 
ATOM 7152 N NH2 . ARG B 2 40  ? 95.317  129.082 95.152  1.00 216.25 ? 50  ARG B NH2 1 
ATOM 7153 N N   . ARG B 2 41  ? 100.329 126.314 100.646 1.00 226.99 ? 51  ARG B N   1 
ATOM 7154 C CA  . ARG B 2 41  ? 99.891  126.278 102.042 1.00 226.99 ? 51  ARG B CA  1 
ATOM 7155 C C   . ARG B 2 41  ? 101.043 126.582 102.997 1.00 226.99 ? 51  ARG B C   1 
ATOM 7156 O O   . ARG B 2 41  ? 101.019 127.585 103.718 1.00 226.99 ? 51  ARG B O   1 
ATOM 7157 C CB  . ARG B 2 41  ? 99.266  124.914 102.357 1.00 226.99 ? 51  ARG B CB  1 
ATOM 7158 C CG  . ARG B 2 41  ? 98.650  124.817 103.744 1.00 226.99 ? 51  ARG B CG  1 
ATOM 7159 C CD  . ARG B 2 41  ? 98.175  123.403 104.048 1.00 226.99 ? 51  ARG B CD  1 
ATOM 7160 N NE  . ARG B 2 41  ? 97.189  122.932 103.082 1.00 226.99 ? 51  ARG B NE  1 
ATOM 7161 C CZ  . ARG B 2 41  ? 95.876  123.053 103.230 1.00 226.99 ? 51  ARG B CZ  1 
ATOM 7162 N NH1 . ARG B 2 41  ? 95.350  123.623 104.301 1.00 226.99 ? 51  ARG B NH1 1 
ATOM 7163 N NH2 . ARG B 2 41  ? 95.071  122.592 102.277 1.00 226.99 ? 51  ARG B NH2 1 
ATOM 7164 N N   . ASN B 2 42  ? 102.064 125.728 103.003 1.00 249.91 ? 52  ASN B N   1 
ATOM 7165 C CA  . ASN B 2 42  ? 103.209 125.854 103.898 1.00 249.91 ? 52  ASN B CA  1 
ATOM 7166 C C   . ASN B 2 42  ? 104.233 124.799 103.502 1.00 249.91 ? 52  ASN B C   1 
ATOM 7167 O O   . ASN B 2 42  ? 103.892 123.776 102.902 1.00 249.91 ? 52  ASN B O   1 
ATOM 7168 C CB  . ASN B 2 42  ? 102.812 125.685 105.371 1.00 249.91 ? 52  ASN B CB  1 
ATOM 7169 C CG  . ASN B 2 42  ? 103.926 126.073 106.326 1.00 249.91 ? 52  ASN B CG  1 
ATOM 7170 O OD1 . ASN B 2 42  ? 104.679 125.222 106.800 1.00 249.91 ? 52  ASN B OD1 1 
ATOM 7171 N ND2 . ASN B 2 42  ? 104.036 127.365 106.611 1.00 249.91 ? 52  ASN B ND2 1 
ATOM 7172 N N   . VAL B 2 43  ? 105.490 125.061 103.846 1.00 268.24 ? 53  VAL B N   1 
ATOM 7173 C CA  . VAL B 2 43  ? 106.572 124.128 103.551 1.00 268.24 ? 53  VAL B CA  1 
ATOM 7174 C C   . VAL B 2 43  ? 106.640 123.038 104.614 1.00 268.24 ? 53  VAL B C   1 
ATOM 7175 O O   . VAL B 2 43  ? 105.727 122.889 105.426 1.00 268.24 ? 53  VAL B O   1 
ATOM 7176 C CB  . VAL B 2 43  ? 107.923 124.858 103.437 1.00 268.24 ? 53  VAL B CB  1 
ATOM 7177 C CG1 . VAL B 2 43  ? 108.248 125.580 104.736 1.00 268.24 ? 53  VAL B CG1 1 
ATOM 7178 C CG2 . VAL B 2 43  ? 109.027 123.874 103.076 1.00 268.24 ? 53  VAL B CG2 1 
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