data_9B3Y
# 
_entry.id   9B3Y 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9B3Y         pdb_00009b3y 10.2210/pdb9b3y/pdb 
WWPDB D_1000282659 ?            ?                   
EMDB  EMD-44160    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-02-26 ? 
2 'EM metadata'     1 0 2025-02-26 ? 
3 'Half map'        1 0 2025-02-26 1 
4 'Half map'        1 0 2025-02-26 2 
5 Image             1 0 2025-02-26 ? 
6 'Primary map'     1 0 2025-02-26 ? 
7 'Structure model' 1 1 2025-03-05 ? 
8 'EM metadata'     1 1 2025-03-05 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Half map'        repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 Image             repository 'Initial release' ? ? 
6 6 'Primary map'     repository 'Initial release' ? ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 7 'Structure model' 'Data collection'      
2 7 'Structure model' 'Database references'  
3 8 'EM metadata'     'Database references'  
4 8 'EM metadata'     'Experimental summary' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 7 'Structure model' citation        
2 7 'Structure model' citation_author 
3 7 'Structure model' em_admin        
4 8 'EM metadata'     citation        
5 8 'EM metadata'     citation_author 
6 8 'EM metadata'     em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  7 'Structure model' '_citation.country'                 
2  7 'Structure model' '_citation.journal_abbrev'          
3  7 'Structure model' '_citation.journal_id_CSD'          
4  7 'Structure model' '_citation.journal_id_ISSN'         
5  7 'Structure model' '_citation.pdbx_database_id_DOI'    
6  7 'Structure model' '_citation.pdbx_database_id_PubMed' 
7  7 'Structure model' '_citation.title'                   
8  7 'Structure model' '_citation.year'                    
9  7 'Structure model' '_citation_author.identifier_ORCID' 
10 7 'Structure model' '_citation_author.name'             
11 7 'Structure model' '_em_admin.last_update'             
12 8 'EM metadata'     '_citation.country'                 
13 8 'EM metadata'     '_citation.journal_abbrev'          
14 8 'EM metadata'     '_citation.journal_id_CSD'          
15 8 'EM metadata'     '_citation.journal_id_ISSN'         
16 8 'EM metadata'     '_citation.pdbx_database_id_DOI'    
17 8 'EM metadata'     '_citation.pdbx_database_id_PubMed' 
18 8 'EM metadata'     '_citation.title'                   
19 8 'EM metadata'     '_citation.year'                    
20 8 'EM metadata'     '_citation_author.identifier_ORCID' 
21 8 'EM metadata'     '_citation_author.name'             
22 8 'EM metadata'     '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9B3Y 
_pdbx_database_status.recvd_initial_deposition_date   2024-03-20 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'rat TRPV2 E724A/D725A bound to probenecid' 
_pdbx_database_related.db_id          EMD-44160 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              vmb@pennmedicine.upenn.edu 
_pdbx_contact_author.name_first         Vera 
_pdbx_contact_author.name_last          Moiseenkova-Bell 
_pdbx_contact_author.name_mi            Y 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-0589-4053 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Rocereta, J.A.'         1 0000-0002-3142-7846 
'Pumroy, R.A.'           2 0000-0002-6200-6083 
'Moiseenkova-Bell, V.Y.' 3 0000-0002-0589-4053 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Nat.Struct.Mol.Biol. 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           1545-9985 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Structural insights into TRPV2 modulation by probenecid.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41594-025-01494-9 
_citation.pdbx_database_id_PubMed   39972168 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Rocereta, J.A.'       1 ?                   
primary 'Sturhahn, T.'         2 ?                   
primary 'Pumroy, R.A.'         3 0000-0002-6200-6083 
primary 'Fricke, T.C.'         4 ?                   
primary 'Herzog, C.'           5 ?                   
primary 'Leffler, A.'          6 0000-0003-1121-6387 
primary 'Moiseenkova-Bell, V.' 7 0000-0002-0589-4053 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Transient receptor potential cation channel subfamily V member 2' 86696.844 4 ? E724A,D725A ? ? 
2 non-polymer syn 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE                    522.632   4 ? ?           ? ? 
3 non-polymer syn '4-(dipropylsulfamoyl)benzoic acid'                                285.359   4 ? ?           ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        
'TrpV2,Osm-9-like TRP channel 2,OTRPC2,Stretch-activated channel 2B,Vanilloid receptor-like protein 1,VRL-1' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MTSASSPPAFRLETSDGDEEGNAEVNKGKQEPPPMESPFQREDRNSSPQIKVNLNFIKRPPKNTSAPSQQEPDRFDRDRL
FSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDE
FYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLE
ATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFS
GPYQPLSRKFTEWCYGPVRVSLYDLSSVDSWEKNSVLEIIAFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNFACY
LVYMFIFTVVAYHQPSLDQPAIPSSKATFGESMLLLGHILILLGGIYLLLGQLWYFWRRRLFIWISFMDSYFEILFLLQA
LLTVLSQVLRFMETEWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSR
EARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNM
LIALMSETVNHVADNSWSIWKLQKAISVLEMENGYWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEEVNWAAWEKTLP
TLSAAPSGPGITGNKKNPTSKPGKNSASEEDHLPLQVLQSP
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MTSASSPPAFRLETSDGDEEGNAEVNKGKQEPPPMESPFQREDRNSSPQIKVNLNFIKRPPKNTSAPSQQEPDRFDRDRL
FSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDE
FYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLE
ATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFS
GPYQPLSRKFTEWCYGPVRVSLYDLSSVDSWEKNSVLEIIAFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNFACY
LVYMFIFTVVAYHQPSLDQPAIPSSKATFGESMLLLGHILILLGGIYLLLGQLWYFWRRRLFIWISFMDSYFEILFLLQA
LLTVLSQVLRFMETEWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSR
EARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNM
LIALMSETVNHVADNSWSIWKLQKAISVLEMENGYWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEEVNWAAWEKTLP
TLSAAPSGPGITGNKKNPTSKPGKNSASEEDHLPLQVLQSP
;
_entity_poly.pdbx_strand_id                 A,B,C,D 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE PEX 
3 '4-(dipropylsulfamoyl)benzoic acid'             RTO 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   THR n 
1 3   SER n 
1 4   ALA n 
1 5   SER n 
1 6   SER n 
1 7   PRO n 
1 8   PRO n 
1 9   ALA n 
1 10  PHE n 
1 11  ARG n 
1 12  LEU n 
1 13  GLU n 
1 14  THR n 
1 15  SER n 
1 16  ASP n 
1 17  GLY n 
1 18  ASP n 
1 19  GLU n 
1 20  GLU n 
1 21  GLY n 
1 22  ASN n 
1 23  ALA n 
1 24  GLU n 
1 25  VAL n 
1 26  ASN n 
1 27  LYS n 
1 28  GLY n 
1 29  LYS n 
1 30  GLN n 
1 31  GLU n 
1 32  PRO n 
1 33  PRO n 
1 34  PRO n 
1 35  MET n 
1 36  GLU n 
1 37  SER n 
1 38  PRO n 
1 39  PHE n 
1 40  GLN n 
1 41  ARG n 
1 42  GLU n 
1 43  ASP n 
1 44  ARG n 
1 45  ASN n 
1 46  SER n 
1 47  SER n 
1 48  PRO n 
1 49  GLN n 
1 50  ILE n 
1 51  LYS n 
1 52  VAL n 
1 53  ASN n 
1 54  LEU n 
1 55  ASN n 
1 56  PHE n 
1 57  ILE n 
1 58  LYS n 
1 59  ARG n 
1 60  PRO n 
1 61  PRO n 
1 62  LYS n 
1 63  ASN n 
1 64  THR n 
1 65  SER n 
1 66  ALA n 
1 67  PRO n 
1 68  SER n 
1 69  GLN n 
1 70  GLN n 
1 71  GLU n 
1 72  PRO n 
1 73  ASP n 
1 74  ARG n 
1 75  PHE n 
1 76  ASP n 
1 77  ARG n 
1 78  ASP n 
1 79  ARG n 
1 80  LEU n 
1 81  PHE n 
1 82  SER n 
1 83  VAL n 
1 84  VAL n 
1 85  SER n 
1 86  ARG n 
1 87  GLY n 
1 88  VAL n 
1 89  PRO n 
1 90  GLU n 
1 91  GLU n 
1 92  LEU n 
1 93  THR n 
1 94  GLY n 
1 95  LEU n 
1 96  LEU n 
1 97  GLU n 
1 98  TYR n 
1 99  LEU n 
1 100 ARG n 
1 101 TRP n 
1 102 ASN n 
1 103 SER n 
1 104 LYS n 
1 105 TYR n 
1 106 LEU n 
1 107 THR n 
1 108 ASP n 
1 109 SER n 
1 110 ALA n 
1 111 TYR n 
1 112 THR n 
1 113 GLU n 
1 114 GLY n 
1 115 SER n 
1 116 THR n 
1 117 GLY n 
1 118 LYS n 
1 119 THR n 
1 120 CYS n 
1 121 LEU n 
1 122 MET n 
1 123 LYS n 
1 124 ALA n 
1 125 VAL n 
1 126 LEU n 
1 127 ASN n 
1 128 LEU n 
1 129 GLN n 
1 130 ASP n 
1 131 GLY n 
1 132 VAL n 
1 133 ASN n 
1 134 ALA n 
1 135 CYS n 
1 136 ILE n 
1 137 MET n 
1 138 PRO n 
1 139 LEU n 
1 140 LEU n 
1 141 GLN n 
1 142 ILE n 
1 143 ASP n 
1 144 LYS n 
1 145 ASP n 
1 146 SER n 
1 147 GLY n 
1 148 ASN n 
1 149 PRO n 
1 150 LYS n 
1 151 LEU n 
1 152 LEU n 
1 153 VAL n 
1 154 ASN n 
1 155 ALA n 
1 156 GLN n 
1 157 CYS n 
1 158 THR n 
1 159 ASP n 
1 160 GLU n 
1 161 PHE n 
1 162 TYR n 
1 163 GLN n 
1 164 GLY n 
1 165 HIS n 
1 166 SER n 
1 167 ALA n 
1 168 LEU n 
1 169 HIS n 
1 170 ILE n 
1 171 ALA n 
1 172 ILE n 
1 173 GLU n 
1 174 LYS n 
1 175 ARG n 
1 176 SER n 
1 177 LEU n 
1 178 GLN n 
1 179 CYS n 
1 180 VAL n 
1 181 LYS n 
1 182 LEU n 
1 183 LEU n 
1 184 VAL n 
1 185 GLU n 
1 186 ASN n 
1 187 GLY n 
1 188 ALA n 
1 189 ASP n 
1 190 VAL n 
1 191 HIS n 
1 192 LEU n 
1 193 ARG n 
1 194 ALA n 
1 195 CYS n 
1 196 GLY n 
1 197 ARG n 
1 198 PHE n 
1 199 PHE n 
1 200 GLN n 
1 201 LYS n 
1 202 HIS n 
1 203 GLN n 
1 204 GLY n 
1 205 THR n 
1 206 CYS n 
1 207 PHE n 
1 208 TYR n 
1 209 PHE n 
1 210 GLY n 
1 211 GLU n 
1 212 LEU n 
1 213 PRO n 
1 214 LEU n 
1 215 SER n 
1 216 LEU n 
1 217 ALA n 
1 218 ALA n 
1 219 CYS n 
1 220 THR n 
1 221 LYS n 
1 222 GLN n 
1 223 TRP n 
1 224 ASP n 
1 225 VAL n 
1 226 VAL n 
1 227 THR n 
1 228 TYR n 
1 229 LEU n 
1 230 LEU n 
1 231 GLU n 
1 232 ASN n 
1 233 PRO n 
1 234 HIS n 
1 235 GLN n 
1 236 PRO n 
1 237 ALA n 
1 238 SER n 
1 239 LEU n 
1 240 GLU n 
1 241 ALA n 
1 242 THR n 
1 243 ASP n 
1 244 SER n 
1 245 LEU n 
1 246 GLY n 
1 247 ASN n 
1 248 THR n 
1 249 VAL n 
1 250 LEU n 
1 251 HIS n 
1 252 ALA n 
1 253 LEU n 
1 254 VAL n 
1 255 MET n 
1 256 ILE n 
1 257 ALA n 
1 258 ASP n 
1 259 ASN n 
1 260 SER n 
1 261 PRO n 
1 262 GLU n 
1 263 ASN n 
1 264 SER n 
1 265 ALA n 
1 266 LEU n 
1 267 VAL n 
1 268 ILE n 
1 269 HIS n 
1 270 MET n 
1 271 TYR n 
1 272 ASP n 
1 273 GLY n 
1 274 LEU n 
1 275 LEU n 
1 276 GLN n 
1 277 MET n 
1 278 GLY n 
1 279 ALA n 
1 280 ARG n 
1 281 LEU n 
1 282 CYS n 
1 283 PRO n 
1 284 THR n 
1 285 VAL n 
1 286 GLN n 
1 287 LEU n 
1 288 GLU n 
1 289 GLU n 
1 290 ILE n 
1 291 SER n 
1 292 ASN n 
1 293 HIS n 
1 294 GLN n 
1 295 GLY n 
1 296 LEU n 
1 297 THR n 
1 298 PRO n 
1 299 LEU n 
1 300 LYS n 
1 301 LEU n 
1 302 ALA n 
1 303 ALA n 
1 304 LYS n 
1 305 GLU n 
1 306 GLY n 
1 307 LYS n 
1 308 ILE n 
1 309 GLU n 
1 310 ILE n 
1 311 PHE n 
1 312 ARG n 
1 313 HIS n 
1 314 ILE n 
1 315 LEU n 
1 316 GLN n 
1 317 ARG n 
1 318 GLU n 
1 319 PHE n 
1 320 SER n 
1 321 GLY n 
1 322 PRO n 
1 323 TYR n 
1 324 GLN n 
1 325 PRO n 
1 326 LEU n 
1 327 SER n 
1 328 ARG n 
1 329 LYS n 
1 330 PHE n 
1 331 THR n 
1 332 GLU n 
1 333 TRP n 
1 334 CYS n 
1 335 TYR n 
1 336 GLY n 
1 337 PRO n 
1 338 VAL n 
1 339 ARG n 
1 340 VAL n 
1 341 SER n 
1 342 LEU n 
1 343 TYR n 
1 344 ASP n 
1 345 LEU n 
1 346 SER n 
1 347 SER n 
1 348 VAL n 
1 349 ASP n 
1 350 SER n 
1 351 TRP n 
1 352 GLU n 
1 353 LYS n 
1 354 ASN n 
1 355 SER n 
1 356 VAL n 
1 357 LEU n 
1 358 GLU n 
1 359 ILE n 
1 360 ILE n 
1 361 ALA n 
1 362 PHE n 
1 363 HIS n 
1 364 CYS n 
1 365 LYS n 
1 366 SER n 
1 367 PRO n 
1 368 ASN n 
1 369 ARG n 
1 370 HIS n 
1 371 ARG n 
1 372 MET n 
1 373 VAL n 
1 374 VAL n 
1 375 LEU n 
1 376 GLU n 
1 377 PRO n 
1 378 LEU n 
1 379 ASN n 
1 380 LYS n 
1 381 LEU n 
1 382 LEU n 
1 383 GLN n 
1 384 GLU n 
1 385 LYS n 
1 386 TRP n 
1 387 ASP n 
1 388 ARG n 
1 389 LEU n 
1 390 VAL n 
1 391 SER n 
1 392 ARG n 
1 393 PHE n 
1 394 PHE n 
1 395 PHE n 
1 396 ASN n 
1 397 PHE n 
1 398 ALA n 
1 399 CYS n 
1 400 TYR n 
1 401 LEU n 
1 402 VAL n 
1 403 TYR n 
1 404 MET n 
1 405 PHE n 
1 406 ILE n 
1 407 PHE n 
1 408 THR n 
1 409 VAL n 
1 410 VAL n 
1 411 ALA n 
1 412 TYR n 
1 413 HIS n 
1 414 GLN n 
1 415 PRO n 
1 416 SER n 
1 417 LEU n 
1 418 ASP n 
1 419 GLN n 
1 420 PRO n 
1 421 ALA n 
1 422 ILE n 
1 423 PRO n 
1 424 SER n 
1 425 SER n 
1 426 LYS n 
1 427 ALA n 
1 428 THR n 
1 429 PHE n 
1 430 GLY n 
1 431 GLU n 
1 432 SER n 
1 433 MET n 
1 434 LEU n 
1 435 LEU n 
1 436 LEU n 
1 437 GLY n 
1 438 HIS n 
1 439 ILE n 
1 440 LEU n 
1 441 ILE n 
1 442 LEU n 
1 443 LEU n 
1 444 GLY n 
1 445 GLY n 
1 446 ILE n 
1 447 TYR n 
1 448 LEU n 
1 449 LEU n 
1 450 LEU n 
1 451 GLY n 
1 452 GLN n 
1 453 LEU n 
1 454 TRP n 
1 455 TYR n 
1 456 PHE n 
1 457 TRP n 
1 458 ARG n 
1 459 ARG n 
1 460 ARG n 
1 461 LEU n 
1 462 PHE n 
1 463 ILE n 
1 464 TRP n 
1 465 ILE n 
1 466 SER n 
1 467 PHE n 
1 468 MET n 
1 469 ASP n 
1 470 SER n 
1 471 TYR n 
1 472 PHE n 
1 473 GLU n 
1 474 ILE n 
1 475 LEU n 
1 476 PHE n 
1 477 LEU n 
1 478 LEU n 
1 479 GLN n 
1 480 ALA n 
1 481 LEU n 
1 482 LEU n 
1 483 THR n 
1 484 VAL n 
1 485 LEU n 
1 486 SER n 
1 487 GLN n 
1 488 VAL n 
1 489 LEU n 
1 490 ARG n 
1 491 PHE n 
1 492 MET n 
1 493 GLU n 
1 494 THR n 
1 495 GLU n 
1 496 TRP n 
1 497 TYR n 
1 498 LEU n 
1 499 PRO n 
1 500 LEU n 
1 501 LEU n 
1 502 VAL n 
1 503 LEU n 
1 504 SER n 
1 505 LEU n 
1 506 VAL n 
1 507 LEU n 
1 508 GLY n 
1 509 TRP n 
1 510 LEU n 
1 511 ASN n 
1 512 LEU n 
1 513 LEU n 
1 514 TYR n 
1 515 TYR n 
1 516 THR n 
1 517 ARG n 
1 518 GLY n 
1 519 PHE n 
1 520 GLN n 
1 521 HIS n 
1 522 THR n 
1 523 GLY n 
1 524 ILE n 
1 525 TYR n 
1 526 SER n 
1 527 VAL n 
1 528 MET n 
1 529 ILE n 
1 530 GLN n 
1 531 LYS n 
1 532 VAL n 
1 533 ILE n 
1 534 LEU n 
1 535 ARG n 
1 536 ASP n 
1 537 LEU n 
1 538 LEU n 
1 539 ARG n 
1 540 PHE n 
1 541 LEU n 
1 542 LEU n 
1 543 VAL n 
1 544 TYR n 
1 545 LEU n 
1 546 VAL n 
1 547 PHE n 
1 548 LEU n 
1 549 PHE n 
1 550 GLY n 
1 551 PHE n 
1 552 ALA n 
1 553 VAL n 
1 554 ALA n 
1 555 LEU n 
1 556 VAL n 
1 557 SER n 
1 558 LEU n 
1 559 SER n 
1 560 ARG n 
1 561 GLU n 
1 562 ALA n 
1 563 ARG n 
1 564 SER n 
1 565 PRO n 
1 566 LYS n 
1 567 ALA n 
1 568 PRO n 
1 569 GLU n 
1 570 ASP n 
1 571 ASN n 
1 572 ASN n 
1 573 SER n 
1 574 THR n 
1 575 VAL n 
1 576 THR n 
1 577 GLU n 
1 578 GLN n 
1 579 PRO n 
1 580 THR n 
1 581 VAL n 
1 582 GLY n 
1 583 GLN n 
1 584 GLU n 
1 585 GLU n 
1 586 GLU n 
1 587 PRO n 
1 588 ALA n 
1 589 PRO n 
1 590 TYR n 
1 591 ARG n 
1 592 SER n 
1 593 ILE n 
1 594 LEU n 
1 595 ASP n 
1 596 ALA n 
1 597 SER n 
1 598 LEU n 
1 599 GLU n 
1 600 LEU n 
1 601 PHE n 
1 602 LYS n 
1 603 PHE n 
1 604 THR n 
1 605 ILE n 
1 606 GLY n 
1 607 MET n 
1 608 GLY n 
1 609 GLU n 
1 610 LEU n 
1 611 ALA n 
1 612 PHE n 
1 613 GLN n 
1 614 GLU n 
1 615 GLN n 
1 616 LEU n 
1 617 ARG n 
1 618 PHE n 
1 619 ARG n 
1 620 GLY n 
1 621 VAL n 
1 622 VAL n 
1 623 LEU n 
1 624 LEU n 
1 625 LEU n 
1 626 LEU n 
1 627 LEU n 
1 628 ALA n 
1 629 TYR n 
1 630 VAL n 
1 631 LEU n 
1 632 LEU n 
1 633 THR n 
1 634 TYR n 
1 635 VAL n 
1 636 LEU n 
1 637 LEU n 
1 638 LEU n 
1 639 ASN n 
1 640 MET n 
1 641 LEU n 
1 642 ILE n 
1 643 ALA n 
1 644 LEU n 
1 645 MET n 
1 646 SER n 
1 647 GLU n 
1 648 THR n 
1 649 VAL n 
1 650 ASN n 
1 651 HIS n 
1 652 VAL n 
1 653 ALA n 
1 654 ASP n 
1 655 ASN n 
1 656 SER n 
1 657 TRP n 
1 658 SER n 
1 659 ILE n 
1 660 TRP n 
1 661 LYS n 
1 662 LEU n 
1 663 GLN n 
1 664 LYS n 
1 665 ALA n 
1 666 ILE n 
1 667 SER n 
1 668 VAL n 
1 669 LEU n 
1 670 GLU n 
1 671 MET n 
1 672 GLU n 
1 673 ASN n 
1 674 GLY n 
1 675 TYR n 
1 676 TRP n 
1 677 TRP n 
1 678 CYS n 
1 679 ARG n 
1 680 ARG n 
1 681 LYS n 
1 682 LYS n 
1 683 HIS n 
1 684 ARG n 
1 685 GLU n 
1 686 GLY n 
1 687 ARG n 
1 688 LEU n 
1 689 LEU n 
1 690 LYS n 
1 691 VAL n 
1 692 GLY n 
1 693 THR n 
1 694 ARG n 
1 695 GLY n 
1 696 ASP n 
1 697 GLY n 
1 698 THR n 
1 699 PRO n 
1 700 ASP n 
1 701 GLU n 
1 702 ARG n 
1 703 TRP n 
1 704 CYS n 
1 705 PHE n 
1 706 ARG n 
1 707 VAL n 
1 708 GLU n 
1 709 GLU n 
1 710 VAL n 
1 711 ASN n 
1 712 TRP n 
1 713 ALA n 
1 714 ALA n 
1 715 TRP n 
1 716 GLU n 
1 717 LYS n 
1 718 THR n 
1 719 LEU n 
1 720 PRO n 
1 721 THR n 
1 722 LEU n 
1 723 SER n 
1 724 ALA n 
1 725 ALA n 
1 726 PRO n 
1 727 SER n 
1 728 GLY n 
1 729 PRO n 
1 730 GLY n 
1 731 ILE n 
1 732 THR n 
1 733 GLY n 
1 734 ASN n 
1 735 LYS n 
1 736 LYS n 
1 737 ASN n 
1 738 PRO n 
1 739 THR n 
1 740 SER n 
1 741 LYS n 
1 742 PRO n 
1 743 GLY n 
1 744 LYS n 
1 745 ASN n 
1 746 SER n 
1 747 ALA n 
1 748 SER n 
1 749 GLU n 
1 750 GLU n 
1 751 ASP n 
1 752 HIS n 
1 753 LEU n 
1 754 PRO n 
1 755 LEU n 
1 756 GLN n 
1 757 VAL n 
1 758 LEU n 
1 759 GLN n 
1 760 SER n 
1 761 PRO n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   761 
_entity_src_gen.gene_src_common_name               'Norway rat' 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'Trpv2, Sac2b, Vrl1' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Rattus norvegicus' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     10116 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Saccharomyces cerevisiae' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     4932 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                         ? 'C3 H7 N O2'        89.093  
ARG 'L-peptide linking' y ARGININE                                        ? 'C6 H15 N4 O2 1'    175.209 
ASN 'L-peptide linking' y ASPARAGINE                                      ? 'C4 H8 N2 O3'       132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                                 ? 'C4 H7 N O4'        133.103 
CYS 'L-peptide linking' y CYSTEINE                                        ? 'C3 H7 N O2 S'      121.158 
GLN 'L-peptide linking' y GLUTAMINE                                       ? 'C5 H10 N2 O3'      146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                                 ? 'C5 H9 N O4'        147.129 
GLY 'peptide linking'   y GLYCINE                                         ? 'C2 H5 N O2'        75.067  
HIS 'L-peptide linking' y HISTIDINE                                       ? 'C6 H10 N3 O2 1'    156.162 
ILE 'L-peptide linking' y ISOLEUCINE                                      ? 'C6 H13 N O2'       131.173 
LEU 'L-peptide linking' y LEUCINE                                         ? 'C6 H13 N O2'       131.173 
LYS 'L-peptide linking' y LYSINE                                          ? 'C6 H15 N2 O2 1'    147.195 
MET 'L-peptide linking' y METHIONINE                                      ? 'C5 H11 N O2 S'     149.211 
PEX non-polymer         . 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE ? 'C25 H49 N O8 P -1' 522.632 
PHE 'L-peptide linking' y PHENYLALANINE                                   ? 'C9 H11 N O2'       165.189 
PRO 'L-peptide linking' y PROLINE                                         ? 'C5 H9 N O2'        115.130 
RTO non-polymer         . '4-(dipropylsulfamoyl)benzoic acid'             ? 'C13 H19 N O4 S'    285.359 
SER 'L-peptide linking' y SERINE                                          ? 'C3 H7 N O3'        105.093 
THR 'L-peptide linking' y THREONINE                                       ? 'C4 H9 N O3'        119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                      ? 'C11 H12 N2 O2'     204.225 
TYR 'L-peptide linking' y TYROSINE                                        ? 'C9 H11 N O3'       181.189 
VAL 'L-peptide linking' y VALINE                                          ? 'C5 H11 N O2'       117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   THR 2   2   ?   ?   ?   A . n 
A 1 3   SER 3   3   ?   ?   ?   A . n 
A 1 4   ALA 4   4   ?   ?   ?   A . n 
A 1 5   SER 5   5   ?   ?   ?   A . n 
A 1 6   SER 6   6   ?   ?   ?   A . n 
A 1 7   PRO 7   7   ?   ?   ?   A . n 
A 1 8   PRO 8   8   ?   ?   ?   A . n 
A 1 9   ALA 9   9   ?   ?   ?   A . n 
A 1 10  PHE 10  10  ?   ?   ?   A . n 
A 1 11  ARG 11  11  ?   ?   ?   A . n 
A 1 12  LEU 12  12  ?   ?   ?   A . n 
A 1 13  GLU 13  13  ?   ?   ?   A . n 
A 1 14  THR 14  14  ?   ?   ?   A . n 
A 1 15  SER 15  15  ?   ?   ?   A . n 
A 1 16  ASP 16  16  ?   ?   ?   A . n 
A 1 17  GLY 17  17  ?   ?   ?   A . n 
A 1 18  ASP 18  18  ?   ?   ?   A . n 
A 1 19  GLU 19  19  ?   ?   ?   A . n 
A 1 20  GLU 20  20  ?   ?   ?   A . n 
A 1 21  GLY 21  21  ?   ?   ?   A . n 
A 1 22  ASN 22  22  ?   ?   ?   A . n 
A 1 23  ALA 23  23  ?   ?   ?   A . n 
A 1 24  GLU 24  24  ?   ?   ?   A . n 
A 1 25  VAL 25  25  ?   ?   ?   A . n 
A 1 26  ASN 26  26  ?   ?   ?   A . n 
A 1 27  LYS 27  27  ?   ?   ?   A . n 
A 1 28  GLY 28  28  ?   ?   ?   A . n 
A 1 29  LYS 29  29  ?   ?   ?   A . n 
A 1 30  GLN 30  30  ?   ?   ?   A . n 
A 1 31  GLU 31  31  ?   ?   ?   A . n 
A 1 32  PRO 32  32  ?   ?   ?   A . n 
A 1 33  PRO 33  33  ?   ?   ?   A . n 
A 1 34  PRO 34  34  ?   ?   ?   A . n 
A 1 35  MET 35  35  ?   ?   ?   A . n 
A 1 36  GLU 36  36  ?   ?   ?   A . n 
A 1 37  SER 37  37  ?   ?   ?   A . n 
A 1 38  PRO 38  38  ?   ?   ?   A . n 
A 1 39  PHE 39  39  ?   ?   ?   A . n 
A 1 40  GLN 40  40  ?   ?   ?   A . n 
A 1 41  ARG 41  41  ?   ?   ?   A . n 
A 1 42  GLU 42  42  ?   ?   ?   A . n 
A 1 43  ASP 43  43  ?   ?   ?   A . n 
A 1 44  ARG 44  44  ?   ?   ?   A . n 
A 1 45  ASN 45  45  ?   ?   ?   A . n 
A 1 46  SER 46  46  ?   ?   ?   A . n 
A 1 47  SER 47  47  ?   ?   ?   A . n 
A 1 48  PRO 48  48  ?   ?   ?   A . n 
A 1 49  GLN 49  49  ?   ?   ?   A . n 
A 1 50  ILE 50  50  ?   ?   ?   A . n 
A 1 51  LYS 51  51  ?   ?   ?   A . n 
A 1 52  VAL 52  52  ?   ?   ?   A . n 
A 1 53  ASN 53  53  ?   ?   ?   A . n 
A 1 54  LEU 54  54  ?   ?   ?   A . n 
A 1 55  ASN 55  55  ?   ?   ?   A . n 
A 1 56  PHE 56  56  ?   ?   ?   A . n 
A 1 57  ILE 57  57  ?   ?   ?   A . n 
A 1 58  LYS 58  58  ?   ?   ?   A . n 
A 1 59  ARG 59  59  ?   ?   ?   A . n 
A 1 60  PRO 60  60  ?   ?   ?   A . n 
A 1 61  PRO 61  61  ?   ?   ?   A . n 
A 1 62  LYS 62  62  ?   ?   ?   A . n 
A 1 63  ASN 63  63  ?   ?   ?   A . n 
A 1 64  THR 64  64  ?   ?   ?   A . n 
A 1 65  SER 65  65  ?   ?   ?   A . n 
A 1 66  ALA 66  66  ?   ?   ?   A . n 
A 1 67  PRO 67  67  ?   ?   ?   A . n 
A 1 68  SER 68  68  ?   ?   ?   A . n 
A 1 69  GLN 69  69  ?   ?   ?   A . n 
A 1 70  GLN 70  70  ?   ?   ?   A . n 
A 1 71  GLU 71  71  ?   ?   ?   A . n 
A 1 72  PRO 72  72  ?   ?   ?   A . n 
A 1 73  ASP 73  73  ?   ?   ?   A . n 
A 1 74  ARG 74  74  74  ARG ARG A . n 
A 1 75  PHE 75  75  75  PHE PHE A . n 
A 1 76  ASP 76  76  76  ASP ASP A . n 
A 1 77  ARG 77  77  77  ARG ARG A . n 
A 1 78  ASP 78  78  78  ASP ASP A . n 
A 1 79  ARG 79  79  79  ARG ARG A . n 
A 1 80  LEU 80  80  80  LEU LEU A . n 
A 1 81  PHE 81  81  81  PHE PHE A . n 
A 1 82  SER 82  82  82  SER SER A . n 
A 1 83  VAL 83  83  83  VAL VAL A . n 
A 1 84  VAL 84  84  84  VAL VAL A . n 
A 1 85  SER 85  85  85  SER SER A . n 
A 1 86  ARG 86  86  86  ARG ARG A . n 
A 1 87  GLY 87  87  87  GLY GLY A . n 
A 1 88  VAL 88  88  88  VAL VAL A . n 
A 1 89  PRO 89  89  89  PRO PRO A . n 
A 1 90  GLU 90  90  90  GLU GLU A . n 
A 1 91  GLU 91  91  91  GLU GLU A . n 
A 1 92  LEU 92  92  92  LEU LEU A . n 
A 1 93  THR 93  93  93  THR THR A . n 
A 1 94  GLY 94  94  94  GLY GLY A . n 
A 1 95  LEU 95  95  95  LEU LEU A . n 
A 1 96  LEU 96  96  96  LEU LEU A . n 
A 1 97  GLU 97  97  97  GLU GLU A . n 
A 1 98  TYR 98  98  98  TYR TYR A . n 
A 1 99  LEU 99  99  99  LEU LEU A . n 
A 1 100 ARG 100 100 100 ARG ARG A . n 
A 1 101 TRP 101 101 101 TRP TRP A . n 
A 1 102 ASN 102 102 102 ASN ASN A . n 
A 1 103 SER 103 103 103 SER SER A . n 
A 1 104 LYS 104 104 104 LYS LYS A . n 
A 1 105 TYR 105 105 105 TYR TYR A . n 
A 1 106 LEU 106 106 106 LEU LEU A . n 
A 1 107 THR 107 107 107 THR THR A . n 
A 1 108 ASP 108 108 108 ASP ASP A . n 
A 1 109 SER 109 109 109 SER SER A . n 
A 1 110 ALA 110 110 110 ALA ALA A . n 
A 1 111 TYR 111 111 111 TYR TYR A . n 
A 1 112 THR 112 112 112 THR THR A . n 
A 1 113 GLU 113 113 113 GLU GLU A . n 
A 1 114 GLY 114 114 114 GLY GLY A . n 
A 1 115 SER 115 115 115 SER SER A . n 
A 1 116 THR 116 116 116 THR THR A . n 
A 1 117 GLY 117 117 117 GLY GLY A . n 
A 1 118 LYS 118 118 118 LYS LYS A . n 
A 1 119 THR 119 119 119 THR THR A . n 
A 1 120 CYS 120 120 120 CYS CYS A . n 
A 1 121 LEU 121 121 121 LEU LEU A . n 
A 1 122 MET 122 122 122 MET MET A . n 
A 1 123 LYS 123 123 123 LYS LYS A . n 
A 1 124 ALA 124 124 124 ALA ALA A . n 
A 1 125 VAL 125 125 125 VAL VAL A . n 
A 1 126 LEU 126 126 126 LEU LEU A . n 
A 1 127 ASN 127 127 127 ASN ASN A . n 
A 1 128 LEU 128 128 128 LEU LEU A . n 
A 1 129 GLN 129 129 129 GLN GLN A . n 
A 1 130 ASP 130 130 130 ASP ASP A . n 
A 1 131 GLY 131 131 131 GLY GLY A . n 
A 1 132 VAL 132 132 132 VAL VAL A . n 
A 1 133 ASN 133 133 133 ASN ASN A . n 
A 1 134 ALA 134 134 134 ALA ALA A . n 
A 1 135 CYS 135 135 135 CYS CYS A . n 
A 1 136 ILE 136 136 136 ILE ILE A . n 
A 1 137 MET 137 137 137 MET MET A . n 
A 1 138 PRO 138 138 138 PRO PRO A . n 
A 1 139 LEU 139 139 139 LEU LEU A . n 
A 1 140 LEU 140 140 140 LEU LEU A . n 
A 1 141 GLN 141 141 141 GLN GLN A . n 
A 1 142 ILE 142 142 142 ILE ILE A . n 
A 1 143 ASP 143 143 143 ASP ASP A . n 
A 1 144 LYS 144 144 144 LYS LYS A . n 
A 1 145 ASP 145 145 145 ASP ASP A . n 
A 1 146 SER 146 146 146 SER SER A . n 
A 1 147 GLY 147 147 147 GLY GLY A . n 
A 1 148 ASN 148 148 148 ASN ASN A . n 
A 1 149 PRO 149 149 149 PRO PRO A . n 
A 1 150 LYS 150 150 150 LYS LYS A . n 
A 1 151 LEU 151 151 151 LEU LEU A . n 
A 1 152 LEU 152 152 152 LEU LEU A . n 
A 1 153 VAL 153 153 153 VAL VAL A . n 
A 1 154 ASN 154 154 154 ASN ASN A . n 
A 1 155 ALA 155 155 155 ALA ALA A . n 
A 1 156 GLN 156 156 156 GLN GLN A . n 
A 1 157 CYS 157 157 157 CYS CYS A . n 
A 1 158 THR 158 158 158 THR THR A . n 
A 1 159 ASP 159 159 159 ASP ASP A . n 
A 1 160 GLU 160 160 160 GLU GLU A . n 
A 1 161 PHE 161 161 161 PHE PHE A . n 
A 1 162 TYR 162 162 162 TYR TYR A . n 
A 1 163 GLN 163 163 163 GLN GLN A . n 
A 1 164 GLY 164 164 164 GLY GLY A . n 
A 1 165 HIS 165 165 165 HIS HIS A . n 
A 1 166 SER 166 166 166 SER SER A . n 
A 1 167 ALA 167 167 167 ALA ALA A . n 
A 1 168 LEU 168 168 168 LEU LEU A . n 
A 1 169 HIS 169 169 169 HIS HIS A . n 
A 1 170 ILE 170 170 170 ILE ILE A . n 
A 1 171 ALA 171 171 171 ALA ALA A . n 
A 1 172 ILE 172 172 172 ILE ILE A . n 
A 1 173 GLU 173 173 173 GLU GLU A . n 
A 1 174 LYS 174 174 174 LYS LYS A . n 
A 1 175 ARG 175 175 175 ARG ARG A . n 
A 1 176 SER 176 176 176 SER SER A . n 
A 1 177 LEU 177 177 177 LEU LEU A . n 
A 1 178 GLN 178 178 178 GLN GLN A . n 
A 1 179 CYS 179 179 179 CYS CYS A . n 
A 1 180 VAL 180 180 180 VAL VAL A . n 
A 1 181 LYS 181 181 181 LYS LYS A . n 
A 1 182 LEU 182 182 182 LEU LEU A . n 
A 1 183 LEU 183 183 183 LEU LEU A . n 
A 1 184 VAL 184 184 184 VAL VAL A . n 
A 1 185 GLU 185 185 185 GLU GLU A . n 
A 1 186 ASN 186 186 186 ASN ASN A . n 
A 1 187 GLY 187 187 187 GLY GLY A . n 
A 1 188 ALA 188 188 188 ALA ALA A . n 
A 1 189 ASP 189 189 189 ASP ASP A . n 
A 1 190 VAL 190 190 190 VAL VAL A . n 
A 1 191 HIS 191 191 191 HIS HIS A . n 
A 1 192 LEU 192 192 192 LEU LEU A . n 
A 1 193 ARG 193 193 193 ARG ARG A . n 
A 1 194 ALA 194 194 194 ALA ALA A . n 
A 1 195 CYS 195 195 195 CYS CYS A . n 
A 1 196 GLY 196 196 196 GLY GLY A . n 
A 1 197 ARG 197 197 197 ARG ARG A . n 
A 1 198 PHE 198 198 198 PHE PHE A . n 
A 1 199 PHE 199 199 199 PHE PHE A . n 
A 1 200 GLN 200 200 200 GLN GLN A . n 
A 1 201 LYS 201 201 201 LYS LYS A . n 
A 1 202 HIS 202 202 202 HIS HIS A . n 
A 1 203 GLN 203 203 203 GLN GLN A . n 
A 1 204 GLY 204 204 204 GLY GLY A . n 
A 1 205 THR 205 205 205 THR THR A . n 
A 1 206 CYS 206 206 206 CYS CYS A . n 
A 1 207 PHE 207 207 207 PHE PHE A . n 
A 1 208 TYR 208 208 208 TYR TYR A . n 
A 1 209 PHE 209 209 209 PHE PHE A . n 
A 1 210 GLY 210 210 210 GLY GLY A . n 
A 1 211 GLU 211 211 211 GLU GLU A . n 
A 1 212 LEU 212 212 212 LEU LEU A . n 
A 1 213 PRO 213 213 213 PRO PRO A . n 
A 1 214 LEU 214 214 214 LEU LEU A . n 
A 1 215 SER 215 215 215 SER SER A . n 
A 1 216 LEU 216 216 216 LEU LEU A . n 
A 1 217 ALA 217 217 217 ALA ALA A . n 
A 1 218 ALA 218 218 218 ALA ALA A . n 
A 1 219 CYS 219 219 219 CYS CYS A . n 
A 1 220 THR 220 220 220 THR THR A . n 
A 1 221 LYS 221 221 221 LYS LYS A . n 
A 1 222 GLN 222 222 222 GLN GLN A . n 
A 1 223 TRP 223 223 223 TRP TRP A . n 
A 1 224 ASP 224 224 224 ASP ASP A . n 
A 1 225 VAL 225 225 225 VAL VAL A . n 
A 1 226 VAL 226 226 226 VAL VAL A . n 
A 1 227 THR 227 227 227 THR THR A . n 
A 1 228 TYR 228 228 228 TYR TYR A . n 
A 1 229 LEU 229 229 229 LEU LEU A . n 
A 1 230 LEU 230 230 230 LEU LEU A . n 
A 1 231 GLU 231 231 231 GLU GLU A . n 
A 1 232 ASN 232 232 232 ASN ASN A . n 
A 1 233 PRO 233 233 233 PRO PRO A . n 
A 1 234 HIS 234 234 234 HIS HIS A . n 
A 1 235 GLN 235 235 235 GLN GLN A . n 
A 1 236 PRO 236 236 236 PRO PRO A . n 
A 1 237 ALA 237 237 237 ALA ALA A . n 
A 1 238 SER 238 238 238 SER SER A . n 
A 1 239 LEU 239 239 239 LEU LEU A . n 
A 1 240 GLU 240 240 240 GLU GLU A . n 
A 1 241 ALA 241 241 241 ALA ALA A . n 
A 1 242 THR 242 242 242 THR THR A . n 
A 1 243 ASP 243 243 243 ASP ASP A . n 
A 1 244 SER 244 244 244 SER SER A . n 
A 1 245 LEU 245 245 245 LEU LEU A . n 
A 1 246 GLY 246 246 246 GLY GLY A . n 
A 1 247 ASN 247 247 247 ASN ASN A . n 
A 1 248 THR 248 248 248 THR THR A . n 
A 1 249 VAL 249 249 249 VAL VAL A . n 
A 1 250 LEU 250 250 250 LEU LEU A . n 
A 1 251 HIS 251 251 251 HIS HIS A . n 
A 1 252 ALA 252 252 252 ALA ALA A . n 
A 1 253 LEU 253 253 253 LEU LEU A . n 
A 1 254 VAL 254 254 254 VAL VAL A . n 
A 1 255 MET 255 255 255 MET MET A . n 
A 1 256 ILE 256 256 256 ILE ILE A . n 
A 1 257 ALA 257 257 257 ALA ALA A . n 
A 1 258 ASP 258 258 258 ASP ASP A . n 
A 1 259 ASN 259 259 259 ASN ASN A . n 
A 1 260 SER 260 260 260 SER SER A . n 
A 1 261 PRO 261 261 261 PRO PRO A . n 
A 1 262 GLU 262 262 262 GLU GLU A . n 
A 1 263 ASN 263 263 263 ASN ASN A . n 
A 1 264 SER 264 264 264 SER SER A . n 
A 1 265 ALA 265 265 265 ALA ALA A . n 
A 1 266 LEU 266 266 266 LEU LEU A . n 
A 1 267 VAL 267 267 267 VAL VAL A . n 
A 1 268 ILE 268 268 268 ILE ILE A . n 
A 1 269 HIS 269 269 269 HIS HIS A . n 
A 1 270 MET 270 270 270 MET MET A . n 
A 1 271 TYR 271 271 271 TYR TYR A . n 
A 1 272 ASP 272 272 272 ASP ASP A . n 
A 1 273 GLY 273 273 273 GLY GLY A . n 
A 1 274 LEU 274 274 274 LEU LEU A . n 
A 1 275 LEU 275 275 275 LEU LEU A . n 
A 1 276 GLN 276 276 276 GLN GLN A . n 
A 1 277 MET 277 277 277 MET MET A . n 
A 1 278 GLY 278 278 278 GLY GLY A . n 
A 1 279 ALA 279 279 279 ALA ALA A . n 
A 1 280 ARG 280 280 280 ARG ARG A . n 
A 1 281 LEU 281 281 281 LEU LEU A . n 
A 1 282 CYS 282 282 282 CYS CYS A . n 
A 1 283 PRO 283 283 283 PRO PRO A . n 
A 1 284 THR 284 284 284 THR THR A . n 
A 1 285 VAL 285 285 285 VAL VAL A . n 
A 1 286 GLN 286 286 286 GLN GLN A . n 
A 1 287 LEU 287 287 287 LEU LEU A . n 
A 1 288 GLU 288 288 288 GLU GLU A . n 
A 1 289 GLU 289 289 289 GLU GLU A . n 
A 1 290 ILE 290 290 290 ILE ILE A . n 
A 1 291 SER 291 291 291 SER SER A . n 
A 1 292 ASN 292 292 292 ASN ASN A . n 
A 1 293 HIS 293 293 293 HIS HIS A . n 
A 1 294 GLN 294 294 294 GLN GLN A . n 
A 1 295 GLY 295 295 295 GLY GLY A . n 
A 1 296 LEU 296 296 296 LEU LEU A . n 
A 1 297 THR 297 297 297 THR THR A . n 
A 1 298 PRO 298 298 298 PRO PRO A . n 
A 1 299 LEU 299 299 299 LEU LEU A . n 
A 1 300 LYS 300 300 300 LYS LYS A . n 
A 1 301 LEU 301 301 301 LEU LEU A . n 
A 1 302 ALA 302 302 302 ALA ALA A . n 
A 1 303 ALA 303 303 303 ALA ALA A . n 
A 1 304 LYS 304 304 304 LYS LYS A . n 
A 1 305 GLU 305 305 305 GLU GLU A . n 
A 1 306 GLY 306 306 306 GLY GLY A . n 
A 1 307 LYS 307 307 307 LYS LYS A . n 
A 1 308 ILE 308 308 308 ILE ILE A . n 
A 1 309 GLU 309 309 309 GLU GLU A . n 
A 1 310 ILE 310 310 310 ILE ILE A . n 
A 1 311 PHE 311 311 311 PHE PHE A . n 
A 1 312 ARG 312 312 312 ARG ARG A . n 
A 1 313 HIS 313 313 313 HIS HIS A . n 
A 1 314 ILE 314 314 314 ILE ILE A . n 
A 1 315 LEU 315 315 315 LEU LEU A . n 
A 1 316 GLN 316 316 316 GLN GLN A . n 
A 1 317 ARG 317 317 317 ARG ARG A . n 
A 1 318 GLU 318 318 318 GLU GLU A . n 
A 1 319 PHE 319 319 319 PHE PHE A . n 
A 1 320 SER 320 320 320 SER SER A . n 
A 1 321 GLY 321 321 321 GLY GLY A . n 
A 1 322 PRO 322 322 322 PRO PRO A . n 
A 1 323 TYR 323 323 323 TYR TYR A . n 
A 1 324 GLN 324 324 324 GLN GLN A . n 
A 1 325 PRO 325 325 325 PRO PRO A . n 
A 1 326 LEU 326 326 326 LEU LEU A . n 
A 1 327 SER 327 327 327 SER SER A . n 
A 1 328 ARG 328 328 328 ARG ARG A . n 
A 1 329 LYS 329 329 329 LYS LYS A . n 
A 1 330 PHE 330 330 330 PHE PHE A . n 
A 1 331 THR 331 331 331 THR THR A . n 
A 1 332 GLU 332 332 332 GLU GLU A . n 
A 1 333 TRP 333 333 333 TRP TRP A . n 
A 1 334 CYS 334 334 334 CYS CYS A . n 
A 1 335 TYR 335 335 335 TYR TYR A . n 
A 1 336 GLY 336 336 336 GLY GLY A . n 
A 1 337 PRO 337 337 337 PRO PRO A . n 
A 1 338 VAL 338 338 338 VAL VAL A . n 
A 1 339 ARG 339 339 339 ARG ARG A . n 
A 1 340 VAL 340 340 340 VAL VAL A . n 
A 1 341 SER 341 341 341 SER SER A . n 
A 1 342 LEU 342 342 342 LEU LEU A . n 
A 1 343 TYR 343 343 343 TYR TYR A . n 
A 1 344 ASP 344 344 344 ASP ASP A . n 
A 1 345 LEU 345 345 345 LEU LEU A . n 
A 1 346 SER 346 346 346 SER SER A . n 
A 1 347 SER 347 347 347 SER SER A . n 
A 1 348 VAL 348 348 348 VAL VAL A . n 
A 1 349 ASP 349 349 349 ASP ASP A . n 
A 1 350 SER 350 350 350 SER SER A . n 
A 1 351 TRP 351 351 351 TRP TRP A . n 
A 1 352 GLU 352 352 352 GLU GLU A . n 
A 1 353 LYS 353 353 353 LYS LYS A . n 
A 1 354 ASN 354 354 354 ASN ASN A . n 
A 1 355 SER 355 355 355 SER SER A . n 
A 1 356 VAL 356 356 356 VAL VAL A . n 
A 1 357 LEU 357 357 357 LEU LEU A . n 
A 1 358 GLU 358 358 358 GLU GLU A . n 
A 1 359 ILE 359 359 359 ILE ILE A . n 
A 1 360 ILE 360 360 360 ILE ILE A . n 
A 1 361 ALA 361 361 361 ALA ALA A . n 
A 1 362 PHE 362 362 362 PHE PHE A . n 
A 1 363 HIS 363 363 363 HIS HIS A . n 
A 1 364 CYS 364 364 364 CYS CYS A . n 
A 1 365 LYS 365 365 365 LYS LYS A . n 
A 1 366 SER 366 366 366 SER SER A . n 
A 1 367 PRO 367 367 367 PRO PRO A . n 
A 1 368 ASN 368 368 368 ASN ASN A . n 
A 1 369 ARG 369 369 369 ARG ARG A . n 
A 1 370 HIS 370 370 370 HIS HIS A . n 
A 1 371 ARG 371 371 371 ARG ARG A . n 
A 1 372 MET 372 372 372 MET MET A . n 
A 1 373 VAL 373 373 373 VAL VAL A . n 
A 1 374 VAL 374 374 374 VAL VAL A . n 
A 1 375 LEU 375 375 375 LEU LEU A . n 
A 1 376 GLU 376 376 376 GLU GLU A . n 
A 1 377 PRO 377 377 377 PRO PRO A . n 
A 1 378 LEU 378 378 378 LEU LEU A . n 
A 1 379 ASN 379 379 379 ASN ASN A . n 
A 1 380 LYS 380 380 380 LYS LYS A . n 
A 1 381 LEU 381 381 381 LEU LEU A . n 
A 1 382 LEU 382 382 382 LEU LEU A . n 
A 1 383 GLN 383 383 383 GLN GLN A . n 
A 1 384 GLU 384 384 384 GLU GLU A . n 
A 1 385 LYS 385 385 385 LYS LYS A . n 
A 1 386 TRP 386 386 386 TRP TRP A . n 
A 1 387 ASP 387 387 387 ASP ASP A . n 
A 1 388 ARG 388 388 388 ARG ARG A . n 
A 1 389 LEU 389 389 389 LEU LEU A . n 
A 1 390 VAL 390 390 390 VAL VAL A . n 
A 1 391 SER 391 391 391 SER SER A . n 
A 1 392 ARG 392 392 392 ARG ARG A . n 
A 1 393 PHE 393 393 393 PHE PHE A . n 
A 1 394 PHE 394 394 394 PHE PHE A . n 
A 1 395 PHE 395 395 395 PHE PHE A . n 
A 1 396 ASN 396 396 396 ASN ASN A . n 
A 1 397 PHE 397 397 397 PHE PHE A . n 
A 1 398 ALA 398 398 398 ALA ALA A . n 
A 1 399 CYS 399 399 399 CYS CYS A . n 
A 1 400 TYR 400 400 400 TYR TYR A . n 
A 1 401 LEU 401 401 401 LEU LEU A . n 
A 1 402 VAL 402 402 402 VAL VAL A . n 
A 1 403 TYR 403 403 403 TYR TYR A . n 
A 1 404 MET 404 404 404 MET MET A . n 
A 1 405 PHE 405 405 405 PHE PHE A . n 
A 1 406 ILE 406 406 406 ILE ILE A . n 
A 1 407 PHE 407 407 407 PHE PHE A . n 
A 1 408 THR 408 408 408 THR THR A . n 
A 1 409 VAL 409 409 409 VAL VAL A . n 
A 1 410 VAL 410 410 410 VAL VAL A . n 
A 1 411 ALA 411 411 411 ALA ALA A . n 
A 1 412 TYR 412 412 412 TYR TYR A . n 
A 1 413 HIS 413 413 413 HIS HIS A . n 
A 1 414 GLN 414 414 414 GLN GLN A . n 
A 1 415 PRO 415 415 415 PRO PRO A . n 
A 1 416 SER 416 416 416 SER SER A . n 
A 1 417 LEU 417 417 417 LEU LEU A . n 
A 1 418 ASP 418 418 ?   ?   ?   A . n 
A 1 419 GLN 419 419 ?   ?   ?   A . n 
A 1 420 PRO 420 420 ?   ?   ?   A . n 
A 1 421 ALA 421 421 ?   ?   ?   A . n 
A 1 422 ILE 422 422 ?   ?   ?   A . n 
A 1 423 PRO 423 423 ?   ?   ?   A . n 
A 1 424 SER 424 424 ?   ?   ?   A . n 
A 1 425 SER 425 425 ?   ?   ?   A . n 
A 1 426 LYS 426 426 ?   ?   ?   A . n 
A 1 427 ALA 427 427 ?   ?   ?   A . n 
A 1 428 THR 428 428 ?   ?   ?   A . n 
A 1 429 PHE 429 429 429 PHE PHE A . n 
A 1 430 GLY 430 430 430 GLY GLY A . n 
A 1 431 GLU 431 431 431 GLU GLU A . n 
A 1 432 SER 432 432 432 SER SER A . n 
A 1 433 MET 433 433 433 MET MET A . n 
A 1 434 LEU 434 434 434 LEU LEU A . n 
A 1 435 LEU 435 435 435 LEU LEU A . n 
A 1 436 LEU 436 436 436 LEU LEU A . n 
A 1 437 GLY 437 437 437 GLY GLY A . n 
A 1 438 HIS 438 438 438 HIS HIS A . n 
A 1 439 ILE 439 439 439 ILE ILE A . n 
A 1 440 LEU 440 440 440 LEU LEU A . n 
A 1 441 ILE 441 441 441 ILE ILE A . n 
A 1 442 LEU 442 442 442 LEU LEU A . n 
A 1 443 LEU 443 443 443 LEU LEU A . n 
A 1 444 GLY 444 444 444 GLY GLY A . n 
A 1 445 GLY 445 445 445 GLY GLY A . n 
A 1 446 ILE 446 446 446 ILE ILE A . n 
A 1 447 TYR 447 447 447 TYR TYR A . n 
A 1 448 LEU 448 448 448 LEU LEU A . n 
A 1 449 LEU 449 449 449 LEU LEU A . n 
A 1 450 LEU 450 450 450 LEU LEU A . n 
A 1 451 GLY 451 451 451 GLY GLY A . n 
A 1 452 GLN 452 452 452 GLN GLN A . n 
A 1 453 LEU 453 453 453 LEU LEU A . n 
A 1 454 TRP 454 454 454 TRP TRP A . n 
A 1 455 TYR 455 455 455 TYR TYR A . n 
A 1 456 PHE 456 456 456 PHE PHE A . n 
A 1 457 TRP 457 457 457 TRP TRP A . n 
A 1 458 ARG 458 458 458 ARG ARG A . n 
A 1 459 ARG 459 459 459 ARG ARG A . n 
A 1 460 ARG 460 460 460 ARG ARG A . n 
A 1 461 LEU 461 461 461 LEU LEU A . n 
A 1 462 PHE 462 462 462 PHE PHE A . n 
A 1 463 ILE 463 463 463 ILE ILE A . n 
A 1 464 TRP 464 464 464 TRP TRP A . n 
A 1 465 ILE 465 465 465 ILE ILE A . n 
A 1 466 SER 466 466 466 SER SER A . n 
A 1 467 PHE 467 467 467 PHE PHE A . n 
A 1 468 MET 468 468 468 MET MET A . n 
A 1 469 ASP 469 469 469 ASP ASP A . n 
A 1 470 SER 470 470 470 SER SER A . n 
A 1 471 TYR 471 471 471 TYR TYR A . n 
A 1 472 PHE 472 472 472 PHE PHE A . n 
A 1 473 GLU 473 473 473 GLU GLU A . n 
A 1 474 ILE 474 474 474 ILE ILE A . n 
A 1 475 LEU 475 475 475 LEU LEU A . n 
A 1 476 PHE 476 476 476 PHE PHE A . n 
A 1 477 LEU 477 477 477 LEU LEU A . n 
A 1 478 LEU 478 478 478 LEU LEU A . n 
A 1 479 GLN 479 479 479 GLN GLN A . n 
A 1 480 ALA 480 480 480 ALA ALA A . n 
A 1 481 LEU 481 481 481 LEU LEU A . n 
A 1 482 LEU 482 482 482 LEU LEU A . n 
A 1 483 THR 483 483 483 THR THR A . n 
A 1 484 VAL 484 484 484 VAL VAL A . n 
A 1 485 LEU 485 485 485 LEU LEU A . n 
A 1 486 SER 486 486 486 SER SER A . n 
A 1 487 GLN 487 487 487 GLN GLN A . n 
A 1 488 VAL 488 488 488 VAL VAL A . n 
A 1 489 LEU 489 489 489 LEU LEU A . n 
A 1 490 ARG 490 490 490 ARG ARG A . n 
A 1 491 PHE 491 491 491 PHE PHE A . n 
A 1 492 MET 492 492 492 MET MET A . n 
A 1 493 GLU 493 493 493 GLU GLU A . n 
A 1 494 THR 494 494 494 THR THR A . n 
A 1 495 GLU 495 495 495 GLU GLU A . n 
A 1 496 TRP 496 496 496 TRP TRP A . n 
A 1 497 TYR 497 497 497 TYR TYR A . n 
A 1 498 LEU 498 498 498 LEU LEU A . n 
A 1 499 PRO 499 499 499 PRO PRO A . n 
A 1 500 LEU 500 500 500 LEU LEU A . n 
A 1 501 LEU 501 501 501 LEU LEU A . n 
A 1 502 VAL 502 502 502 VAL VAL A . n 
A 1 503 LEU 503 503 503 LEU LEU A . n 
A 1 504 SER 504 504 504 SER SER A . n 
A 1 505 LEU 505 505 505 LEU LEU A . n 
A 1 506 VAL 506 506 506 VAL VAL A . n 
A 1 507 LEU 507 507 507 LEU LEU A . n 
A 1 508 GLY 508 508 508 GLY GLY A . n 
A 1 509 TRP 509 509 509 TRP TRP A . n 
A 1 510 LEU 510 510 510 LEU LEU A . n 
A 1 511 ASN 511 511 511 ASN ASN A . n 
A 1 512 LEU 512 512 512 LEU LEU A . n 
A 1 513 LEU 513 513 513 LEU LEU A . n 
A 1 514 TYR 514 514 514 TYR TYR A . n 
A 1 515 TYR 515 515 515 TYR TYR A . n 
A 1 516 THR 516 516 516 THR THR A . n 
A 1 517 ARG 517 517 517 ARG ARG A . n 
A 1 518 GLY 518 518 518 GLY GLY A . n 
A 1 519 PHE 519 519 519 PHE PHE A . n 
A 1 520 GLN 520 520 520 GLN GLN A . n 
A 1 521 HIS 521 521 521 HIS HIS A . n 
A 1 522 THR 522 522 522 THR THR A . n 
A 1 523 GLY 523 523 523 GLY GLY A . n 
A 1 524 ILE 524 524 524 ILE ILE A . n 
A 1 525 TYR 525 525 525 TYR TYR A . n 
A 1 526 SER 526 526 526 SER SER A . n 
A 1 527 VAL 527 527 527 VAL VAL A . n 
A 1 528 MET 528 528 528 MET MET A . n 
A 1 529 ILE 529 529 529 ILE ILE A . n 
A 1 530 GLN 530 530 530 GLN GLN A . n 
A 1 531 LYS 531 531 531 LYS LYS A . n 
A 1 532 VAL 532 532 532 VAL VAL A . n 
A 1 533 ILE 533 533 533 ILE ILE A . n 
A 1 534 LEU 534 534 534 LEU LEU A . n 
A 1 535 ARG 535 535 535 ARG ARG A . n 
A 1 536 ASP 536 536 536 ASP ASP A . n 
A 1 537 LEU 537 537 537 LEU LEU A . n 
A 1 538 LEU 538 538 538 LEU LEU A . n 
A 1 539 ARG 539 539 539 ARG ARG A . n 
A 1 540 PHE 540 540 540 PHE PHE A . n 
A 1 541 LEU 541 541 541 LEU LEU A . n 
A 1 542 LEU 542 542 542 LEU LEU A . n 
A 1 543 VAL 543 543 543 VAL VAL A . n 
A 1 544 TYR 544 544 544 TYR TYR A . n 
A 1 545 LEU 545 545 545 LEU LEU A . n 
A 1 546 VAL 546 546 546 VAL VAL A . n 
A 1 547 PHE 547 547 547 PHE PHE A . n 
A 1 548 LEU 548 548 548 LEU LEU A . n 
A 1 549 PHE 549 549 549 PHE PHE A . n 
A 1 550 GLY 550 550 550 GLY GLY A . n 
A 1 551 PHE 551 551 551 PHE PHE A . n 
A 1 552 ALA 552 552 552 ALA ALA A . n 
A 1 553 VAL 553 553 553 VAL VAL A . n 
A 1 554 ALA 554 554 554 ALA ALA A . n 
A 1 555 LEU 555 555 555 LEU LEU A . n 
A 1 556 VAL 556 556 556 VAL VAL A . n 
A 1 557 SER 557 557 557 SER SER A . n 
A 1 558 LEU 558 558 558 LEU LEU A . n 
A 1 559 SER 559 559 559 SER SER A . n 
A 1 560 ARG 560 560 560 ARG ARG A . n 
A 1 561 GLU 561 561 561 GLU GLU A . n 
A 1 562 ALA 562 562 562 ALA ALA A . n 
A 1 563 ARG 563 563 563 ARG ARG A . n 
A 1 564 SER 564 564 ?   ?   ?   A . n 
A 1 565 PRO 565 565 ?   ?   ?   A . n 
A 1 566 LYS 566 566 ?   ?   ?   A . n 
A 1 567 ALA 567 567 ?   ?   ?   A . n 
A 1 568 PRO 568 568 ?   ?   ?   A . n 
A 1 569 GLU 569 569 ?   ?   ?   A . n 
A 1 570 ASP 570 570 ?   ?   ?   A . n 
A 1 571 ASN 571 571 ?   ?   ?   A . n 
A 1 572 ASN 572 572 ?   ?   ?   A . n 
A 1 573 SER 573 573 ?   ?   ?   A . n 
A 1 574 THR 574 574 ?   ?   ?   A . n 
A 1 575 VAL 575 575 ?   ?   ?   A . n 
A 1 576 THR 576 576 ?   ?   ?   A . n 
A 1 577 GLU 577 577 ?   ?   ?   A . n 
A 1 578 GLN 578 578 ?   ?   ?   A . n 
A 1 579 PRO 579 579 ?   ?   ?   A . n 
A 1 580 THR 580 580 ?   ?   ?   A . n 
A 1 581 VAL 581 581 ?   ?   ?   A . n 
A 1 582 GLY 582 582 ?   ?   ?   A . n 
A 1 583 GLN 583 583 ?   ?   ?   A . n 
A 1 584 GLU 584 584 ?   ?   ?   A . n 
A 1 585 GLU 585 585 ?   ?   ?   A . n 
A 1 586 GLU 586 586 ?   ?   ?   A . n 
A 1 587 PRO 587 587 ?   ?   ?   A . n 
A 1 588 ALA 588 588 ?   ?   ?   A . n 
A 1 589 PRO 589 589 589 PRO PRO A . n 
A 1 590 TYR 590 590 590 TYR TYR A . n 
A 1 591 ARG 591 591 591 ARG ARG A . n 
A 1 592 SER 592 592 592 SER SER A . n 
A 1 593 ILE 593 593 593 ILE ILE A . n 
A 1 594 LEU 594 594 594 LEU LEU A . n 
A 1 595 ASP 595 595 595 ASP ASP A . n 
A 1 596 ALA 596 596 596 ALA ALA A . n 
A 1 597 SER 597 597 597 SER SER A . n 
A 1 598 LEU 598 598 598 LEU LEU A . n 
A 1 599 GLU 599 599 599 GLU GLU A . n 
A 1 600 LEU 600 600 600 LEU LEU A . n 
A 1 601 PHE 601 601 601 PHE PHE A . n 
A 1 602 LYS 602 602 602 LYS LYS A . n 
A 1 603 PHE 603 603 603 PHE PHE A . n 
A 1 604 THR 604 604 604 THR THR A . n 
A 1 605 ILE 605 605 605 ILE ILE A . n 
A 1 606 GLY 606 606 606 GLY GLY A . n 
A 1 607 MET 607 607 607 MET MET A . n 
A 1 608 GLY 608 608 608 GLY GLY A . n 
A 1 609 GLU 609 609 609 GLU GLU A . n 
A 1 610 LEU 610 610 610 LEU LEU A . n 
A 1 611 ALA 611 611 611 ALA ALA A . n 
A 1 612 PHE 612 612 612 PHE PHE A . n 
A 1 613 GLN 613 613 613 GLN GLN A . n 
A 1 614 GLU 614 614 614 GLU GLU A . n 
A 1 615 GLN 615 615 615 GLN GLN A . n 
A 1 616 LEU 616 616 616 LEU LEU A . n 
A 1 617 ARG 617 617 617 ARG ARG A . n 
A 1 618 PHE 618 618 618 PHE PHE A . n 
A 1 619 ARG 619 619 619 ARG ARG A . n 
A 1 620 GLY 620 620 620 GLY GLY A . n 
A 1 621 VAL 621 621 621 VAL VAL A . n 
A 1 622 VAL 622 622 622 VAL VAL A . n 
A 1 623 LEU 623 623 623 LEU LEU A . n 
A 1 624 LEU 624 624 624 LEU LEU A . n 
A 1 625 LEU 625 625 625 LEU LEU A . n 
A 1 626 LEU 626 626 626 LEU LEU A . n 
A 1 627 LEU 627 627 627 LEU LEU A . n 
A 1 628 ALA 628 628 628 ALA ALA A . n 
A 1 629 TYR 629 629 629 TYR TYR A . n 
A 1 630 VAL 630 630 630 VAL VAL A . n 
A 1 631 LEU 631 631 631 LEU LEU A . n 
A 1 632 LEU 632 632 632 LEU LEU A . n 
A 1 633 THR 633 633 633 THR THR A . n 
A 1 634 TYR 634 634 634 TYR TYR A . n 
A 1 635 VAL 635 635 635 VAL VAL A . n 
A 1 636 LEU 636 636 636 LEU LEU A . n 
A 1 637 LEU 637 637 637 LEU LEU A . n 
A 1 638 LEU 638 638 638 LEU LEU A . n 
A 1 639 ASN 639 639 639 ASN ASN A . n 
A 1 640 MET 640 640 640 MET MET A . n 
A 1 641 LEU 641 641 641 LEU LEU A . n 
A 1 642 ILE 642 642 642 ILE ILE A . n 
A 1 643 ALA 643 643 643 ALA ALA A . n 
A 1 644 LEU 644 644 644 LEU LEU A . n 
A 1 645 MET 645 645 645 MET MET A . n 
A 1 646 SER 646 646 646 SER SER A . n 
A 1 647 GLU 647 647 647 GLU GLU A . n 
A 1 648 THR 648 648 648 THR THR A . n 
A 1 649 VAL 649 649 649 VAL VAL A . n 
A 1 650 ASN 650 650 650 ASN ASN A . n 
A 1 651 HIS 651 651 651 HIS HIS A . n 
A 1 652 VAL 652 652 652 VAL VAL A . n 
A 1 653 ALA 653 653 653 ALA ALA A . n 
A 1 654 ASP 654 654 654 ASP ASP A . n 
A 1 655 ASN 655 655 655 ASN ASN A . n 
A 1 656 SER 656 656 656 SER SER A . n 
A 1 657 TRP 657 657 657 TRP TRP A . n 
A 1 658 SER 658 658 658 SER SER A . n 
A 1 659 ILE 659 659 659 ILE ILE A . n 
A 1 660 TRP 660 660 660 TRP TRP A . n 
A 1 661 LYS 661 661 661 LYS LYS A . n 
A 1 662 LEU 662 662 662 LEU LEU A . n 
A 1 663 GLN 663 663 663 GLN GLN A . n 
A 1 664 LYS 664 664 664 LYS LYS A . n 
A 1 665 ALA 665 665 665 ALA ALA A . n 
A 1 666 ILE 666 666 666 ILE ILE A . n 
A 1 667 SER 667 667 667 SER SER A . n 
A 1 668 VAL 668 668 668 VAL VAL A . n 
A 1 669 LEU 669 669 669 LEU LEU A . n 
A 1 670 GLU 670 670 670 GLU GLU A . n 
A 1 671 MET 671 671 671 MET MET A . n 
A 1 672 GLU 672 672 672 GLU GLU A . n 
A 1 673 ASN 673 673 673 ASN ASN A . n 
A 1 674 GLY 674 674 674 GLY GLY A . n 
A 1 675 TYR 675 675 675 TYR TYR A . n 
A 1 676 TRP 676 676 676 TRP TRP A . n 
A 1 677 TRP 677 677 677 TRP TRP A . n 
A 1 678 CYS 678 678 678 CYS CYS A . n 
A 1 679 ARG 679 679 679 ARG ARG A . n 
A 1 680 ARG 680 680 680 ARG ARG A . n 
A 1 681 LYS 681 681 681 LYS LYS A . n 
A 1 682 LYS 682 682 682 LYS LYS A . n 
A 1 683 HIS 683 683 683 HIS HIS A . n 
A 1 684 ARG 684 684 684 ARG ARG A . n 
A 1 685 GLU 685 685 685 GLU GLU A . n 
A 1 686 GLY 686 686 686 GLY GLY A . n 
A 1 687 ARG 687 687 687 ARG ARG A . n 
A 1 688 LEU 688 688 688 LEU LEU A . n 
A 1 689 LEU 689 689 689 LEU LEU A . n 
A 1 690 LYS 690 690 690 LYS LYS A . n 
A 1 691 VAL 691 691 691 VAL VAL A . n 
A 1 692 GLY 692 692 692 GLY GLY A . n 
A 1 693 THR 693 693 693 THR THR A . n 
A 1 694 ARG 694 694 694 ARG ARG A . n 
A 1 695 GLY 695 695 ?   ?   ?   A . n 
A 1 696 ASP 696 696 ?   ?   ?   A . n 
A 1 697 GLY 697 697 ?   ?   ?   A . n 
A 1 698 THR 698 698 ?   ?   ?   A . n 
A 1 699 PRO 699 699 699 PRO PRO A . n 
A 1 700 ASP 700 700 700 ASP ASP A . n 
A 1 701 GLU 701 701 701 GLU GLU A . n 
A 1 702 ARG 702 702 702 ARG ARG A . n 
A 1 703 TRP 703 703 703 TRP TRP A . n 
A 1 704 CYS 704 704 704 CYS CYS A . n 
A 1 705 PHE 705 705 705 PHE PHE A . n 
A 1 706 ARG 706 706 706 ARG ARG A . n 
A 1 707 VAL 707 707 707 VAL VAL A . n 
A 1 708 GLU 708 708 708 GLU GLU A . n 
A 1 709 GLU 709 709 709 GLU GLU A . n 
A 1 710 VAL 710 710 710 VAL VAL A . n 
A 1 711 ASN 711 711 711 ASN ASN A . n 
A 1 712 TRP 712 712 712 TRP TRP A . n 
A 1 713 ALA 713 713 713 ALA ALA A . n 
A 1 714 ALA 714 714 714 ALA ALA A . n 
A 1 715 TRP 715 715 715 TRP TRP A . n 
A 1 716 GLU 716 716 716 GLU GLU A . n 
A 1 717 LYS 717 717 717 LYS LYS A . n 
A 1 718 THR 718 718 718 THR THR A . n 
A 1 719 LEU 719 719 719 LEU LEU A . n 
A 1 720 PRO 720 720 ?   ?   ?   A . n 
A 1 721 THR 721 721 ?   ?   ?   A . n 
A 1 722 LEU 722 722 ?   ?   ?   A . n 
A 1 723 SER 723 723 ?   ?   ?   A . n 
A 1 724 ALA 724 724 ?   ?   ?   A . n 
A 1 725 ALA 725 725 ?   ?   ?   A . n 
A 1 726 PRO 726 726 ?   ?   ?   A . n 
A 1 727 SER 727 727 ?   ?   ?   A . n 
A 1 728 GLY 728 728 ?   ?   ?   A . n 
A 1 729 PRO 729 729 ?   ?   ?   A . n 
A 1 730 GLY 730 730 ?   ?   ?   A . n 
A 1 731 ILE 731 731 ?   ?   ?   A . n 
A 1 732 THR 732 732 ?   ?   ?   A . n 
A 1 733 GLY 733 733 ?   ?   ?   A . n 
A 1 734 ASN 734 734 ?   ?   ?   A . n 
A 1 735 LYS 735 735 ?   ?   ?   A . n 
A 1 736 LYS 736 736 ?   ?   ?   A . n 
A 1 737 ASN 737 737 ?   ?   ?   A . n 
A 1 738 PRO 738 738 ?   ?   ?   A . n 
A 1 739 THR 739 739 ?   ?   ?   A . n 
A 1 740 SER 740 740 ?   ?   ?   A . n 
A 1 741 LYS 741 741 ?   ?   ?   A . n 
A 1 742 PRO 742 742 ?   ?   ?   A . n 
A 1 743 GLY 743 743 ?   ?   ?   A . n 
A 1 744 LYS 744 744 ?   ?   ?   A . n 
A 1 745 ASN 745 745 ?   ?   ?   A . n 
A 1 746 SER 746 746 ?   ?   ?   A . n 
A 1 747 ALA 747 747 ?   ?   ?   A . n 
A 1 748 SER 748 748 ?   ?   ?   A . n 
A 1 749 GLU 749 749 ?   ?   ?   A . n 
A 1 750 GLU 750 750 ?   ?   ?   A . n 
A 1 751 ASP 751 751 ?   ?   ?   A . n 
A 1 752 HIS 752 752 ?   ?   ?   A . n 
A 1 753 LEU 753 753 ?   ?   ?   A . n 
A 1 754 PRO 754 754 ?   ?   ?   A . n 
A 1 755 LEU 755 755 ?   ?   ?   A . n 
A 1 756 GLN 756 756 ?   ?   ?   A . n 
A 1 757 VAL 757 757 ?   ?   ?   A . n 
A 1 758 LEU 758 758 ?   ?   ?   A . n 
A 1 759 GLN 759 759 ?   ?   ?   A . n 
A 1 760 SER 760 760 ?   ?   ?   A . n 
A 1 761 PRO 761 761 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   THR 2   2   ?   ?   ?   B . n 
B 1 3   SER 3   3   ?   ?   ?   B . n 
B 1 4   ALA 4   4   ?   ?   ?   B . n 
B 1 5   SER 5   5   ?   ?   ?   B . n 
B 1 6   SER 6   6   ?   ?   ?   B . n 
B 1 7   PRO 7   7   ?   ?   ?   B . n 
B 1 8   PRO 8   8   ?   ?   ?   B . n 
B 1 9   ALA 9   9   ?   ?   ?   B . n 
B 1 10  PHE 10  10  ?   ?   ?   B . n 
B 1 11  ARG 11  11  ?   ?   ?   B . n 
B 1 12  LEU 12  12  ?   ?   ?   B . n 
B 1 13  GLU 13  13  ?   ?   ?   B . n 
B 1 14  THR 14  14  ?   ?   ?   B . n 
B 1 15  SER 15  15  ?   ?   ?   B . n 
B 1 16  ASP 16  16  ?   ?   ?   B . n 
B 1 17  GLY 17  17  ?   ?   ?   B . n 
B 1 18  ASP 18  18  ?   ?   ?   B . n 
B 1 19  GLU 19  19  ?   ?   ?   B . n 
B 1 20  GLU 20  20  ?   ?   ?   B . n 
B 1 21  GLY 21  21  ?   ?   ?   B . n 
B 1 22  ASN 22  22  ?   ?   ?   B . n 
B 1 23  ALA 23  23  ?   ?   ?   B . n 
B 1 24  GLU 24  24  ?   ?   ?   B . n 
B 1 25  VAL 25  25  ?   ?   ?   B . n 
B 1 26  ASN 26  26  ?   ?   ?   B . n 
B 1 27  LYS 27  27  ?   ?   ?   B . n 
B 1 28  GLY 28  28  ?   ?   ?   B . n 
B 1 29  LYS 29  29  ?   ?   ?   B . n 
B 1 30  GLN 30  30  ?   ?   ?   B . n 
B 1 31  GLU 31  31  ?   ?   ?   B . n 
B 1 32  PRO 32  32  ?   ?   ?   B . n 
B 1 33  PRO 33  33  ?   ?   ?   B . n 
B 1 34  PRO 34  34  ?   ?   ?   B . n 
B 1 35  MET 35  35  ?   ?   ?   B . n 
B 1 36  GLU 36  36  ?   ?   ?   B . n 
B 1 37  SER 37  37  ?   ?   ?   B . n 
B 1 38  PRO 38  38  ?   ?   ?   B . n 
B 1 39  PHE 39  39  ?   ?   ?   B . n 
B 1 40  GLN 40  40  ?   ?   ?   B . n 
B 1 41  ARG 41  41  ?   ?   ?   B . n 
B 1 42  GLU 42  42  ?   ?   ?   B . n 
B 1 43  ASP 43  43  ?   ?   ?   B . n 
B 1 44  ARG 44  44  ?   ?   ?   B . n 
B 1 45  ASN 45  45  ?   ?   ?   B . n 
B 1 46  SER 46  46  ?   ?   ?   B . n 
B 1 47  SER 47  47  ?   ?   ?   B . n 
B 1 48  PRO 48  48  ?   ?   ?   B . n 
B 1 49  GLN 49  49  ?   ?   ?   B . n 
B 1 50  ILE 50  50  ?   ?   ?   B . n 
B 1 51  LYS 51  51  ?   ?   ?   B . n 
B 1 52  VAL 52  52  ?   ?   ?   B . n 
B 1 53  ASN 53  53  ?   ?   ?   B . n 
B 1 54  LEU 54  54  ?   ?   ?   B . n 
B 1 55  ASN 55  55  ?   ?   ?   B . n 
B 1 56  PHE 56  56  ?   ?   ?   B . n 
B 1 57  ILE 57  57  ?   ?   ?   B . n 
B 1 58  LYS 58  58  ?   ?   ?   B . n 
B 1 59  ARG 59  59  ?   ?   ?   B . n 
B 1 60  PRO 60  60  ?   ?   ?   B . n 
B 1 61  PRO 61  61  ?   ?   ?   B . n 
B 1 62  LYS 62  62  ?   ?   ?   B . n 
B 1 63  ASN 63  63  ?   ?   ?   B . n 
B 1 64  THR 64  64  ?   ?   ?   B . n 
B 1 65  SER 65  65  ?   ?   ?   B . n 
B 1 66  ALA 66  66  ?   ?   ?   B . n 
B 1 67  PRO 67  67  ?   ?   ?   B . n 
B 1 68  SER 68  68  ?   ?   ?   B . n 
B 1 69  GLN 69  69  ?   ?   ?   B . n 
B 1 70  GLN 70  70  ?   ?   ?   B . n 
B 1 71  GLU 71  71  ?   ?   ?   B . n 
B 1 72  PRO 72  72  ?   ?   ?   B . n 
B 1 73  ASP 73  73  ?   ?   ?   B . n 
B 1 74  ARG 74  74  74  ARG ARG B . n 
B 1 75  PHE 75  75  75  PHE PHE B . n 
B 1 76  ASP 76  76  76  ASP ASP B . n 
B 1 77  ARG 77  77  77  ARG ARG B . n 
B 1 78  ASP 78  78  78  ASP ASP B . n 
B 1 79  ARG 79  79  79  ARG ARG B . n 
B 1 80  LEU 80  80  80  LEU LEU B . n 
B 1 81  PHE 81  81  81  PHE PHE B . n 
B 1 82  SER 82  82  82  SER SER B . n 
B 1 83  VAL 83  83  83  VAL VAL B . n 
B 1 84  VAL 84  84  84  VAL VAL B . n 
B 1 85  SER 85  85  85  SER SER B . n 
B 1 86  ARG 86  86  86  ARG ARG B . n 
B 1 87  GLY 87  87  87  GLY GLY B . n 
B 1 88  VAL 88  88  88  VAL VAL B . n 
B 1 89  PRO 89  89  89  PRO PRO B . n 
B 1 90  GLU 90  90  90  GLU GLU B . n 
B 1 91  GLU 91  91  91  GLU GLU B . n 
B 1 92  LEU 92  92  92  LEU LEU B . n 
B 1 93  THR 93  93  93  THR THR B . n 
B 1 94  GLY 94  94  94  GLY GLY B . n 
B 1 95  LEU 95  95  95  LEU LEU B . n 
B 1 96  LEU 96  96  96  LEU LEU B . n 
B 1 97  GLU 97  97  97  GLU GLU B . n 
B 1 98  TYR 98  98  98  TYR TYR B . n 
B 1 99  LEU 99  99  99  LEU LEU B . n 
B 1 100 ARG 100 100 100 ARG ARG B . n 
B 1 101 TRP 101 101 101 TRP TRP B . n 
B 1 102 ASN 102 102 102 ASN ASN B . n 
B 1 103 SER 103 103 103 SER SER B . n 
B 1 104 LYS 104 104 104 LYS LYS B . n 
B 1 105 TYR 105 105 105 TYR TYR B . n 
B 1 106 LEU 106 106 106 LEU LEU B . n 
B 1 107 THR 107 107 107 THR THR B . n 
B 1 108 ASP 108 108 108 ASP ASP B . n 
B 1 109 SER 109 109 109 SER SER B . n 
B 1 110 ALA 110 110 110 ALA ALA B . n 
B 1 111 TYR 111 111 111 TYR TYR B . n 
B 1 112 THR 112 112 112 THR THR B . n 
B 1 113 GLU 113 113 113 GLU GLU B . n 
B 1 114 GLY 114 114 114 GLY GLY B . n 
B 1 115 SER 115 115 115 SER SER B . n 
B 1 116 THR 116 116 116 THR THR B . n 
B 1 117 GLY 117 117 117 GLY GLY B . n 
B 1 118 LYS 118 118 118 LYS LYS B . n 
B 1 119 THR 119 119 119 THR THR B . n 
B 1 120 CYS 120 120 120 CYS CYS B . n 
B 1 121 LEU 121 121 121 LEU LEU B . n 
B 1 122 MET 122 122 122 MET MET B . n 
B 1 123 LYS 123 123 123 LYS LYS B . n 
B 1 124 ALA 124 124 124 ALA ALA B . n 
B 1 125 VAL 125 125 125 VAL VAL B . n 
B 1 126 LEU 126 126 126 LEU LEU B . n 
B 1 127 ASN 127 127 127 ASN ASN B . n 
B 1 128 LEU 128 128 128 LEU LEU B . n 
B 1 129 GLN 129 129 129 GLN GLN B . n 
B 1 130 ASP 130 130 130 ASP ASP B . n 
B 1 131 GLY 131 131 131 GLY GLY B . n 
B 1 132 VAL 132 132 132 VAL VAL B . n 
B 1 133 ASN 133 133 133 ASN ASN B . n 
B 1 134 ALA 134 134 134 ALA ALA B . n 
B 1 135 CYS 135 135 135 CYS CYS B . n 
B 1 136 ILE 136 136 136 ILE ILE B . n 
B 1 137 MET 137 137 137 MET MET B . n 
B 1 138 PRO 138 138 138 PRO PRO B . n 
B 1 139 LEU 139 139 139 LEU LEU B . n 
B 1 140 LEU 140 140 140 LEU LEU B . n 
B 1 141 GLN 141 141 141 GLN GLN B . n 
B 1 142 ILE 142 142 142 ILE ILE B . n 
B 1 143 ASP 143 143 143 ASP ASP B . n 
B 1 144 LYS 144 144 144 LYS LYS B . n 
B 1 145 ASP 145 145 145 ASP ASP B . n 
B 1 146 SER 146 146 146 SER SER B . n 
B 1 147 GLY 147 147 147 GLY GLY B . n 
B 1 148 ASN 148 148 148 ASN ASN B . n 
B 1 149 PRO 149 149 149 PRO PRO B . n 
B 1 150 LYS 150 150 150 LYS LYS B . n 
B 1 151 LEU 151 151 151 LEU LEU B . n 
B 1 152 LEU 152 152 152 LEU LEU B . n 
B 1 153 VAL 153 153 153 VAL VAL B . n 
B 1 154 ASN 154 154 154 ASN ASN B . n 
B 1 155 ALA 155 155 155 ALA ALA B . n 
B 1 156 GLN 156 156 156 GLN GLN B . n 
B 1 157 CYS 157 157 157 CYS CYS B . n 
B 1 158 THR 158 158 158 THR THR B . n 
B 1 159 ASP 159 159 159 ASP ASP B . n 
B 1 160 GLU 160 160 160 GLU GLU B . n 
B 1 161 PHE 161 161 161 PHE PHE B . n 
B 1 162 TYR 162 162 162 TYR TYR B . n 
B 1 163 GLN 163 163 163 GLN GLN B . n 
B 1 164 GLY 164 164 164 GLY GLY B . n 
B 1 165 HIS 165 165 165 HIS HIS B . n 
B 1 166 SER 166 166 166 SER SER B . n 
B 1 167 ALA 167 167 167 ALA ALA B . n 
B 1 168 LEU 168 168 168 LEU LEU B . n 
B 1 169 HIS 169 169 169 HIS HIS B . n 
B 1 170 ILE 170 170 170 ILE ILE B . n 
B 1 171 ALA 171 171 171 ALA ALA B . n 
B 1 172 ILE 172 172 172 ILE ILE B . n 
B 1 173 GLU 173 173 173 GLU GLU B . n 
B 1 174 LYS 174 174 174 LYS LYS B . n 
B 1 175 ARG 175 175 175 ARG ARG B . n 
B 1 176 SER 176 176 176 SER SER B . n 
B 1 177 LEU 177 177 177 LEU LEU B . n 
B 1 178 GLN 178 178 178 GLN GLN B . n 
B 1 179 CYS 179 179 179 CYS CYS B . n 
B 1 180 VAL 180 180 180 VAL VAL B . n 
B 1 181 LYS 181 181 181 LYS LYS B . n 
B 1 182 LEU 182 182 182 LEU LEU B . n 
B 1 183 LEU 183 183 183 LEU LEU B . n 
B 1 184 VAL 184 184 184 VAL VAL B . n 
B 1 185 GLU 185 185 185 GLU GLU B . n 
B 1 186 ASN 186 186 186 ASN ASN B . n 
B 1 187 GLY 187 187 187 GLY GLY B . n 
B 1 188 ALA 188 188 188 ALA ALA B . n 
B 1 189 ASP 189 189 189 ASP ASP B . n 
B 1 190 VAL 190 190 190 VAL VAL B . n 
B 1 191 HIS 191 191 191 HIS HIS B . n 
B 1 192 LEU 192 192 192 LEU LEU B . n 
B 1 193 ARG 193 193 193 ARG ARG B . n 
B 1 194 ALA 194 194 194 ALA ALA B . n 
B 1 195 CYS 195 195 195 CYS CYS B . n 
B 1 196 GLY 196 196 196 GLY GLY B . n 
B 1 197 ARG 197 197 197 ARG ARG B . n 
B 1 198 PHE 198 198 198 PHE PHE B . n 
B 1 199 PHE 199 199 199 PHE PHE B . n 
B 1 200 GLN 200 200 200 GLN GLN B . n 
B 1 201 LYS 201 201 201 LYS LYS B . n 
B 1 202 HIS 202 202 202 HIS HIS B . n 
B 1 203 GLN 203 203 203 GLN GLN B . n 
B 1 204 GLY 204 204 204 GLY GLY B . n 
B 1 205 THR 205 205 205 THR THR B . n 
B 1 206 CYS 206 206 206 CYS CYS B . n 
B 1 207 PHE 207 207 207 PHE PHE B . n 
B 1 208 TYR 208 208 208 TYR TYR B . n 
B 1 209 PHE 209 209 209 PHE PHE B . n 
B 1 210 GLY 210 210 210 GLY GLY B . n 
B 1 211 GLU 211 211 211 GLU GLU B . n 
B 1 212 LEU 212 212 212 LEU LEU B . n 
B 1 213 PRO 213 213 213 PRO PRO B . n 
B 1 214 LEU 214 214 214 LEU LEU B . n 
B 1 215 SER 215 215 215 SER SER B . n 
B 1 216 LEU 216 216 216 LEU LEU B . n 
B 1 217 ALA 217 217 217 ALA ALA B . n 
B 1 218 ALA 218 218 218 ALA ALA B . n 
B 1 219 CYS 219 219 219 CYS CYS B . n 
B 1 220 THR 220 220 220 THR THR B . n 
B 1 221 LYS 221 221 221 LYS LYS B . n 
B 1 222 GLN 222 222 222 GLN GLN B . n 
B 1 223 TRP 223 223 223 TRP TRP B . n 
B 1 224 ASP 224 224 224 ASP ASP B . n 
B 1 225 VAL 225 225 225 VAL VAL B . n 
B 1 226 VAL 226 226 226 VAL VAL B . n 
B 1 227 THR 227 227 227 THR THR B . n 
B 1 228 TYR 228 228 228 TYR TYR B . n 
B 1 229 LEU 229 229 229 LEU LEU B . n 
B 1 230 LEU 230 230 230 LEU LEU B . n 
B 1 231 GLU 231 231 231 GLU GLU B . n 
B 1 232 ASN 232 232 232 ASN ASN B . n 
B 1 233 PRO 233 233 233 PRO PRO B . n 
B 1 234 HIS 234 234 234 HIS HIS B . n 
B 1 235 GLN 235 235 235 GLN GLN B . n 
B 1 236 PRO 236 236 236 PRO PRO B . n 
B 1 237 ALA 237 237 237 ALA ALA B . n 
B 1 238 SER 238 238 238 SER SER B . n 
B 1 239 LEU 239 239 239 LEU LEU B . n 
B 1 240 GLU 240 240 240 GLU GLU B . n 
B 1 241 ALA 241 241 241 ALA ALA B . n 
B 1 242 THR 242 242 242 THR THR B . n 
B 1 243 ASP 243 243 243 ASP ASP B . n 
B 1 244 SER 244 244 244 SER SER B . n 
B 1 245 LEU 245 245 245 LEU LEU B . n 
B 1 246 GLY 246 246 246 GLY GLY B . n 
B 1 247 ASN 247 247 247 ASN ASN B . n 
B 1 248 THR 248 248 248 THR THR B . n 
B 1 249 VAL 249 249 249 VAL VAL B . n 
B 1 250 LEU 250 250 250 LEU LEU B . n 
B 1 251 HIS 251 251 251 HIS HIS B . n 
B 1 252 ALA 252 252 252 ALA ALA B . n 
B 1 253 LEU 253 253 253 LEU LEU B . n 
B 1 254 VAL 254 254 254 VAL VAL B . n 
B 1 255 MET 255 255 255 MET MET B . n 
B 1 256 ILE 256 256 256 ILE ILE B . n 
B 1 257 ALA 257 257 257 ALA ALA B . n 
B 1 258 ASP 258 258 258 ASP ASP B . n 
B 1 259 ASN 259 259 259 ASN ASN B . n 
B 1 260 SER 260 260 260 SER SER B . n 
B 1 261 PRO 261 261 261 PRO PRO B . n 
B 1 262 GLU 262 262 262 GLU GLU B . n 
B 1 263 ASN 263 263 263 ASN ASN B . n 
B 1 264 SER 264 264 264 SER SER B . n 
B 1 265 ALA 265 265 265 ALA ALA B . n 
B 1 266 LEU 266 266 266 LEU LEU B . n 
B 1 267 VAL 267 267 267 VAL VAL B . n 
B 1 268 ILE 268 268 268 ILE ILE B . n 
B 1 269 HIS 269 269 269 HIS HIS B . n 
B 1 270 MET 270 270 270 MET MET B . n 
B 1 271 TYR 271 271 271 TYR TYR B . n 
B 1 272 ASP 272 272 272 ASP ASP B . n 
B 1 273 GLY 273 273 273 GLY GLY B . n 
B 1 274 LEU 274 274 274 LEU LEU B . n 
B 1 275 LEU 275 275 275 LEU LEU B . n 
B 1 276 GLN 276 276 276 GLN GLN B . n 
B 1 277 MET 277 277 277 MET MET B . n 
B 1 278 GLY 278 278 278 GLY GLY B . n 
B 1 279 ALA 279 279 279 ALA ALA B . n 
B 1 280 ARG 280 280 280 ARG ARG B . n 
B 1 281 LEU 281 281 281 LEU LEU B . n 
B 1 282 CYS 282 282 282 CYS CYS B . n 
B 1 283 PRO 283 283 283 PRO PRO B . n 
B 1 284 THR 284 284 284 THR THR B . n 
B 1 285 VAL 285 285 285 VAL VAL B . n 
B 1 286 GLN 286 286 286 GLN GLN B . n 
B 1 287 LEU 287 287 287 LEU LEU B . n 
B 1 288 GLU 288 288 288 GLU GLU B . n 
B 1 289 GLU 289 289 289 GLU GLU B . n 
B 1 290 ILE 290 290 290 ILE ILE B . n 
B 1 291 SER 291 291 291 SER SER B . n 
B 1 292 ASN 292 292 292 ASN ASN B . n 
B 1 293 HIS 293 293 293 HIS HIS B . n 
B 1 294 GLN 294 294 294 GLN GLN B . n 
B 1 295 GLY 295 295 295 GLY GLY B . n 
B 1 296 LEU 296 296 296 LEU LEU B . n 
B 1 297 THR 297 297 297 THR THR B . n 
B 1 298 PRO 298 298 298 PRO PRO B . n 
B 1 299 LEU 299 299 299 LEU LEU B . n 
B 1 300 LYS 300 300 300 LYS LYS B . n 
B 1 301 LEU 301 301 301 LEU LEU B . n 
B 1 302 ALA 302 302 302 ALA ALA B . n 
B 1 303 ALA 303 303 303 ALA ALA B . n 
B 1 304 LYS 304 304 304 LYS LYS B . n 
B 1 305 GLU 305 305 305 GLU GLU B . n 
B 1 306 GLY 306 306 306 GLY GLY B . n 
B 1 307 LYS 307 307 307 LYS LYS B . n 
B 1 308 ILE 308 308 308 ILE ILE B . n 
B 1 309 GLU 309 309 309 GLU GLU B . n 
B 1 310 ILE 310 310 310 ILE ILE B . n 
B 1 311 PHE 311 311 311 PHE PHE B . n 
B 1 312 ARG 312 312 312 ARG ARG B . n 
B 1 313 HIS 313 313 313 HIS HIS B . n 
B 1 314 ILE 314 314 314 ILE ILE B . n 
B 1 315 LEU 315 315 315 LEU LEU B . n 
B 1 316 GLN 316 316 316 GLN GLN B . n 
B 1 317 ARG 317 317 317 ARG ARG B . n 
B 1 318 GLU 318 318 318 GLU GLU B . n 
B 1 319 PHE 319 319 319 PHE PHE B . n 
B 1 320 SER 320 320 320 SER SER B . n 
B 1 321 GLY 321 321 321 GLY GLY B . n 
B 1 322 PRO 322 322 322 PRO PRO B . n 
B 1 323 TYR 323 323 323 TYR TYR B . n 
B 1 324 GLN 324 324 324 GLN GLN B . n 
B 1 325 PRO 325 325 325 PRO PRO B . n 
B 1 326 LEU 326 326 326 LEU LEU B . n 
B 1 327 SER 327 327 327 SER SER B . n 
B 1 328 ARG 328 328 328 ARG ARG B . n 
B 1 329 LYS 329 329 329 LYS LYS B . n 
B 1 330 PHE 330 330 330 PHE PHE B . n 
B 1 331 THR 331 331 331 THR THR B . n 
B 1 332 GLU 332 332 332 GLU GLU B . n 
B 1 333 TRP 333 333 333 TRP TRP B . n 
B 1 334 CYS 334 334 334 CYS CYS B . n 
B 1 335 TYR 335 335 335 TYR TYR B . n 
B 1 336 GLY 336 336 336 GLY GLY B . n 
B 1 337 PRO 337 337 337 PRO PRO B . n 
B 1 338 VAL 338 338 338 VAL VAL B . n 
B 1 339 ARG 339 339 339 ARG ARG B . n 
B 1 340 VAL 340 340 340 VAL VAL B . n 
B 1 341 SER 341 341 341 SER SER B . n 
B 1 342 LEU 342 342 342 LEU LEU B . n 
B 1 343 TYR 343 343 343 TYR TYR B . n 
B 1 344 ASP 344 344 344 ASP ASP B . n 
B 1 345 LEU 345 345 345 LEU LEU B . n 
B 1 346 SER 346 346 346 SER SER B . n 
B 1 347 SER 347 347 347 SER SER B . n 
B 1 348 VAL 348 348 348 VAL VAL B . n 
B 1 349 ASP 349 349 349 ASP ASP B . n 
B 1 350 SER 350 350 350 SER SER B . n 
B 1 351 TRP 351 351 351 TRP TRP B . n 
B 1 352 GLU 352 352 352 GLU GLU B . n 
B 1 353 LYS 353 353 353 LYS LYS B . n 
B 1 354 ASN 354 354 354 ASN ASN B . n 
B 1 355 SER 355 355 355 SER SER B . n 
B 1 356 VAL 356 356 356 VAL VAL B . n 
B 1 357 LEU 357 357 357 LEU LEU B . n 
B 1 358 GLU 358 358 358 GLU GLU B . n 
B 1 359 ILE 359 359 359 ILE ILE B . n 
B 1 360 ILE 360 360 360 ILE ILE B . n 
B 1 361 ALA 361 361 361 ALA ALA B . n 
B 1 362 PHE 362 362 362 PHE PHE B . n 
B 1 363 HIS 363 363 363 HIS HIS B . n 
B 1 364 CYS 364 364 364 CYS CYS B . n 
B 1 365 LYS 365 365 365 LYS LYS B . n 
B 1 366 SER 366 366 366 SER SER B . n 
B 1 367 PRO 367 367 367 PRO PRO B . n 
B 1 368 ASN 368 368 368 ASN ASN B . n 
B 1 369 ARG 369 369 369 ARG ARG B . n 
B 1 370 HIS 370 370 370 HIS HIS B . n 
B 1 371 ARG 371 371 371 ARG ARG B . n 
B 1 372 MET 372 372 372 MET MET B . n 
B 1 373 VAL 373 373 373 VAL VAL B . n 
B 1 374 VAL 374 374 374 VAL VAL B . n 
B 1 375 LEU 375 375 375 LEU LEU B . n 
B 1 376 GLU 376 376 376 GLU GLU B . n 
B 1 377 PRO 377 377 377 PRO PRO B . n 
B 1 378 LEU 378 378 378 LEU LEU B . n 
B 1 379 ASN 379 379 379 ASN ASN B . n 
B 1 380 LYS 380 380 380 LYS LYS B . n 
B 1 381 LEU 381 381 381 LEU LEU B . n 
B 1 382 LEU 382 382 382 LEU LEU B . n 
B 1 383 GLN 383 383 383 GLN GLN B . n 
B 1 384 GLU 384 384 384 GLU GLU B . n 
B 1 385 LYS 385 385 385 LYS LYS B . n 
B 1 386 TRP 386 386 386 TRP TRP B . n 
B 1 387 ASP 387 387 387 ASP ASP B . n 
B 1 388 ARG 388 388 388 ARG ARG B . n 
B 1 389 LEU 389 389 389 LEU LEU B . n 
B 1 390 VAL 390 390 390 VAL VAL B . n 
B 1 391 SER 391 391 391 SER SER B . n 
B 1 392 ARG 392 392 392 ARG ARG B . n 
B 1 393 PHE 393 393 393 PHE PHE B . n 
B 1 394 PHE 394 394 394 PHE PHE B . n 
B 1 395 PHE 395 395 395 PHE PHE B . n 
B 1 396 ASN 396 396 396 ASN ASN B . n 
B 1 397 PHE 397 397 397 PHE PHE B . n 
B 1 398 ALA 398 398 398 ALA ALA B . n 
B 1 399 CYS 399 399 399 CYS CYS B . n 
B 1 400 TYR 400 400 400 TYR TYR B . n 
B 1 401 LEU 401 401 401 LEU LEU B . n 
B 1 402 VAL 402 402 402 VAL VAL B . n 
B 1 403 TYR 403 403 403 TYR TYR B . n 
B 1 404 MET 404 404 404 MET MET B . n 
B 1 405 PHE 405 405 405 PHE PHE B . n 
B 1 406 ILE 406 406 406 ILE ILE B . n 
B 1 407 PHE 407 407 407 PHE PHE B . n 
B 1 408 THR 408 408 408 THR THR B . n 
B 1 409 VAL 409 409 409 VAL VAL B . n 
B 1 410 VAL 410 410 410 VAL VAL B . n 
B 1 411 ALA 411 411 411 ALA ALA B . n 
B 1 412 TYR 412 412 412 TYR TYR B . n 
B 1 413 HIS 413 413 413 HIS HIS B . n 
B 1 414 GLN 414 414 414 GLN GLN B . n 
B 1 415 PRO 415 415 415 PRO PRO B . n 
B 1 416 SER 416 416 416 SER SER B . n 
B 1 417 LEU 417 417 417 LEU LEU B . n 
B 1 418 ASP 418 418 ?   ?   ?   B . n 
B 1 419 GLN 419 419 ?   ?   ?   B . n 
B 1 420 PRO 420 420 ?   ?   ?   B . n 
B 1 421 ALA 421 421 ?   ?   ?   B . n 
B 1 422 ILE 422 422 ?   ?   ?   B . n 
B 1 423 PRO 423 423 ?   ?   ?   B . n 
B 1 424 SER 424 424 ?   ?   ?   B . n 
B 1 425 SER 425 425 ?   ?   ?   B . n 
B 1 426 LYS 426 426 ?   ?   ?   B . n 
B 1 427 ALA 427 427 ?   ?   ?   B . n 
B 1 428 THR 428 428 ?   ?   ?   B . n 
B 1 429 PHE 429 429 429 PHE PHE B . n 
B 1 430 GLY 430 430 430 GLY GLY B . n 
B 1 431 GLU 431 431 431 GLU GLU B . n 
B 1 432 SER 432 432 432 SER SER B . n 
B 1 433 MET 433 433 433 MET MET B . n 
B 1 434 LEU 434 434 434 LEU LEU B . n 
B 1 435 LEU 435 435 435 LEU LEU B . n 
B 1 436 LEU 436 436 436 LEU LEU B . n 
B 1 437 GLY 437 437 437 GLY GLY B . n 
B 1 438 HIS 438 438 438 HIS HIS B . n 
B 1 439 ILE 439 439 439 ILE ILE B . n 
B 1 440 LEU 440 440 440 LEU LEU B . n 
B 1 441 ILE 441 441 441 ILE ILE B . n 
B 1 442 LEU 442 442 442 LEU LEU B . n 
B 1 443 LEU 443 443 443 LEU LEU B . n 
B 1 444 GLY 444 444 444 GLY GLY B . n 
B 1 445 GLY 445 445 445 GLY GLY B . n 
B 1 446 ILE 446 446 446 ILE ILE B . n 
B 1 447 TYR 447 447 447 TYR TYR B . n 
B 1 448 LEU 448 448 448 LEU LEU B . n 
B 1 449 LEU 449 449 449 LEU LEU B . n 
B 1 450 LEU 450 450 450 LEU LEU B . n 
B 1 451 GLY 451 451 451 GLY GLY B . n 
B 1 452 GLN 452 452 452 GLN GLN B . n 
B 1 453 LEU 453 453 453 LEU LEU B . n 
B 1 454 TRP 454 454 454 TRP TRP B . n 
B 1 455 TYR 455 455 455 TYR TYR B . n 
B 1 456 PHE 456 456 456 PHE PHE B . n 
B 1 457 TRP 457 457 457 TRP TRP B . n 
B 1 458 ARG 458 458 458 ARG ARG B . n 
B 1 459 ARG 459 459 459 ARG ARG B . n 
B 1 460 ARG 460 460 460 ARG ARG B . n 
B 1 461 LEU 461 461 461 LEU LEU B . n 
B 1 462 PHE 462 462 462 PHE PHE B . n 
B 1 463 ILE 463 463 463 ILE ILE B . n 
B 1 464 TRP 464 464 464 TRP TRP B . n 
B 1 465 ILE 465 465 465 ILE ILE B . n 
B 1 466 SER 466 466 466 SER SER B . n 
B 1 467 PHE 467 467 467 PHE PHE B . n 
B 1 468 MET 468 468 468 MET MET B . n 
B 1 469 ASP 469 469 469 ASP ASP B . n 
B 1 470 SER 470 470 470 SER SER B . n 
B 1 471 TYR 471 471 471 TYR TYR B . n 
B 1 472 PHE 472 472 472 PHE PHE B . n 
B 1 473 GLU 473 473 473 GLU GLU B . n 
B 1 474 ILE 474 474 474 ILE ILE B . n 
B 1 475 LEU 475 475 475 LEU LEU B . n 
B 1 476 PHE 476 476 476 PHE PHE B . n 
B 1 477 LEU 477 477 477 LEU LEU B . n 
B 1 478 LEU 478 478 478 LEU LEU B . n 
B 1 479 GLN 479 479 479 GLN GLN B . n 
B 1 480 ALA 480 480 480 ALA ALA B . n 
B 1 481 LEU 481 481 481 LEU LEU B . n 
B 1 482 LEU 482 482 482 LEU LEU B . n 
B 1 483 THR 483 483 483 THR THR B . n 
B 1 484 VAL 484 484 484 VAL VAL B . n 
B 1 485 LEU 485 485 485 LEU LEU B . n 
B 1 486 SER 486 486 486 SER SER B . n 
B 1 487 GLN 487 487 487 GLN GLN B . n 
B 1 488 VAL 488 488 488 VAL VAL B . n 
B 1 489 LEU 489 489 489 LEU LEU B . n 
B 1 490 ARG 490 490 490 ARG ARG B . n 
B 1 491 PHE 491 491 491 PHE PHE B . n 
B 1 492 MET 492 492 492 MET MET B . n 
B 1 493 GLU 493 493 493 GLU GLU B . n 
B 1 494 THR 494 494 494 THR THR B . n 
B 1 495 GLU 495 495 495 GLU GLU B . n 
B 1 496 TRP 496 496 496 TRP TRP B . n 
B 1 497 TYR 497 497 497 TYR TYR B . n 
B 1 498 LEU 498 498 498 LEU LEU B . n 
B 1 499 PRO 499 499 499 PRO PRO B . n 
B 1 500 LEU 500 500 500 LEU LEU B . n 
B 1 501 LEU 501 501 501 LEU LEU B . n 
B 1 502 VAL 502 502 502 VAL VAL B . n 
B 1 503 LEU 503 503 503 LEU LEU B . n 
B 1 504 SER 504 504 504 SER SER B . n 
B 1 505 LEU 505 505 505 LEU LEU B . n 
B 1 506 VAL 506 506 506 VAL VAL B . n 
B 1 507 LEU 507 507 507 LEU LEU B . n 
B 1 508 GLY 508 508 508 GLY GLY B . n 
B 1 509 TRP 509 509 509 TRP TRP B . n 
B 1 510 LEU 510 510 510 LEU LEU B . n 
B 1 511 ASN 511 511 511 ASN ASN B . n 
B 1 512 LEU 512 512 512 LEU LEU B . n 
B 1 513 LEU 513 513 513 LEU LEU B . n 
B 1 514 TYR 514 514 514 TYR TYR B . n 
B 1 515 TYR 515 515 515 TYR TYR B . n 
B 1 516 THR 516 516 516 THR THR B . n 
B 1 517 ARG 517 517 517 ARG ARG B . n 
B 1 518 GLY 518 518 518 GLY GLY B . n 
B 1 519 PHE 519 519 519 PHE PHE B . n 
B 1 520 GLN 520 520 520 GLN GLN B . n 
B 1 521 HIS 521 521 521 HIS HIS B . n 
B 1 522 THR 522 522 522 THR THR B . n 
B 1 523 GLY 523 523 523 GLY GLY B . n 
B 1 524 ILE 524 524 524 ILE ILE B . n 
B 1 525 TYR 525 525 525 TYR TYR B . n 
B 1 526 SER 526 526 526 SER SER B . n 
B 1 527 VAL 527 527 527 VAL VAL B . n 
B 1 528 MET 528 528 528 MET MET B . n 
B 1 529 ILE 529 529 529 ILE ILE B . n 
B 1 530 GLN 530 530 530 GLN GLN B . n 
B 1 531 LYS 531 531 531 LYS LYS B . n 
B 1 532 VAL 532 532 532 VAL VAL B . n 
B 1 533 ILE 533 533 533 ILE ILE B . n 
B 1 534 LEU 534 534 534 LEU LEU B . n 
B 1 535 ARG 535 535 535 ARG ARG B . n 
B 1 536 ASP 536 536 536 ASP ASP B . n 
B 1 537 LEU 537 537 537 LEU LEU B . n 
B 1 538 LEU 538 538 538 LEU LEU B . n 
B 1 539 ARG 539 539 539 ARG ARG B . n 
B 1 540 PHE 540 540 540 PHE PHE B . n 
B 1 541 LEU 541 541 541 LEU LEU B . n 
B 1 542 LEU 542 542 542 LEU LEU B . n 
B 1 543 VAL 543 543 543 VAL VAL B . n 
B 1 544 TYR 544 544 544 TYR TYR B . n 
B 1 545 LEU 545 545 545 LEU LEU B . n 
B 1 546 VAL 546 546 546 VAL VAL B . n 
B 1 547 PHE 547 547 547 PHE PHE B . n 
B 1 548 LEU 548 548 548 LEU LEU B . n 
B 1 549 PHE 549 549 549 PHE PHE B . n 
B 1 550 GLY 550 550 550 GLY GLY B . n 
B 1 551 PHE 551 551 551 PHE PHE B . n 
B 1 552 ALA 552 552 552 ALA ALA B . n 
B 1 553 VAL 553 553 553 VAL VAL B . n 
B 1 554 ALA 554 554 554 ALA ALA B . n 
B 1 555 LEU 555 555 555 LEU LEU B . n 
B 1 556 VAL 556 556 556 VAL VAL B . n 
B 1 557 SER 557 557 557 SER SER B . n 
B 1 558 LEU 558 558 558 LEU LEU B . n 
B 1 559 SER 559 559 559 SER SER B . n 
B 1 560 ARG 560 560 560 ARG ARG B . n 
B 1 561 GLU 561 561 561 GLU GLU B . n 
B 1 562 ALA 562 562 562 ALA ALA B . n 
B 1 563 ARG 563 563 563 ARG ARG B . n 
B 1 564 SER 564 564 ?   ?   ?   B . n 
B 1 565 PRO 565 565 ?   ?   ?   B . n 
B 1 566 LYS 566 566 ?   ?   ?   B . n 
B 1 567 ALA 567 567 ?   ?   ?   B . n 
B 1 568 PRO 568 568 ?   ?   ?   B . n 
B 1 569 GLU 569 569 ?   ?   ?   B . n 
B 1 570 ASP 570 570 ?   ?   ?   B . n 
B 1 571 ASN 571 571 ?   ?   ?   B . n 
B 1 572 ASN 572 572 ?   ?   ?   B . n 
B 1 573 SER 573 573 ?   ?   ?   B . n 
B 1 574 THR 574 574 ?   ?   ?   B . n 
B 1 575 VAL 575 575 ?   ?   ?   B . n 
B 1 576 THR 576 576 ?   ?   ?   B . n 
B 1 577 GLU 577 577 ?   ?   ?   B . n 
B 1 578 GLN 578 578 ?   ?   ?   B . n 
B 1 579 PRO 579 579 ?   ?   ?   B . n 
B 1 580 THR 580 580 ?   ?   ?   B . n 
B 1 581 VAL 581 581 ?   ?   ?   B . n 
B 1 582 GLY 582 582 ?   ?   ?   B . n 
B 1 583 GLN 583 583 ?   ?   ?   B . n 
B 1 584 GLU 584 584 ?   ?   ?   B . n 
B 1 585 GLU 585 585 ?   ?   ?   B . n 
B 1 586 GLU 586 586 ?   ?   ?   B . n 
B 1 587 PRO 587 587 ?   ?   ?   B . n 
B 1 588 ALA 588 588 ?   ?   ?   B . n 
B 1 589 PRO 589 589 589 PRO PRO B . n 
B 1 590 TYR 590 590 590 TYR TYR B . n 
B 1 591 ARG 591 591 591 ARG ARG B . n 
B 1 592 SER 592 592 592 SER SER B . n 
B 1 593 ILE 593 593 593 ILE ILE B . n 
B 1 594 LEU 594 594 594 LEU LEU B . n 
B 1 595 ASP 595 595 595 ASP ASP B . n 
B 1 596 ALA 596 596 596 ALA ALA B . n 
B 1 597 SER 597 597 597 SER SER B . n 
B 1 598 LEU 598 598 598 LEU LEU B . n 
B 1 599 GLU 599 599 599 GLU GLU B . n 
B 1 600 LEU 600 600 600 LEU LEU B . n 
B 1 601 PHE 601 601 601 PHE PHE B . n 
B 1 602 LYS 602 602 602 LYS LYS B . n 
B 1 603 PHE 603 603 603 PHE PHE B . n 
B 1 604 THR 604 604 604 THR THR B . n 
B 1 605 ILE 605 605 605 ILE ILE B . n 
B 1 606 GLY 606 606 606 GLY GLY B . n 
B 1 607 MET 607 607 607 MET MET B . n 
B 1 608 GLY 608 608 608 GLY GLY B . n 
B 1 609 GLU 609 609 609 GLU GLU B . n 
B 1 610 LEU 610 610 610 LEU LEU B . n 
B 1 611 ALA 611 611 611 ALA ALA B . n 
B 1 612 PHE 612 612 612 PHE PHE B . n 
B 1 613 GLN 613 613 613 GLN GLN B . n 
B 1 614 GLU 614 614 614 GLU GLU B . n 
B 1 615 GLN 615 615 615 GLN GLN B . n 
B 1 616 LEU 616 616 616 LEU LEU B . n 
B 1 617 ARG 617 617 617 ARG ARG B . n 
B 1 618 PHE 618 618 618 PHE PHE B . n 
B 1 619 ARG 619 619 619 ARG ARG B . n 
B 1 620 GLY 620 620 620 GLY GLY B . n 
B 1 621 VAL 621 621 621 VAL VAL B . n 
B 1 622 VAL 622 622 622 VAL VAL B . n 
B 1 623 LEU 623 623 623 LEU LEU B . n 
B 1 624 LEU 624 624 624 LEU LEU B . n 
B 1 625 LEU 625 625 625 LEU LEU B . n 
B 1 626 LEU 626 626 626 LEU LEU B . n 
B 1 627 LEU 627 627 627 LEU LEU B . n 
B 1 628 ALA 628 628 628 ALA ALA B . n 
B 1 629 TYR 629 629 629 TYR TYR B . n 
B 1 630 VAL 630 630 630 VAL VAL B . n 
B 1 631 LEU 631 631 631 LEU LEU B . n 
B 1 632 LEU 632 632 632 LEU LEU B . n 
B 1 633 THR 633 633 633 THR THR B . n 
B 1 634 TYR 634 634 634 TYR TYR B . n 
B 1 635 VAL 635 635 635 VAL VAL B . n 
B 1 636 LEU 636 636 636 LEU LEU B . n 
B 1 637 LEU 637 637 637 LEU LEU B . n 
B 1 638 LEU 638 638 638 LEU LEU B . n 
B 1 639 ASN 639 639 639 ASN ASN B . n 
B 1 640 MET 640 640 640 MET MET B . n 
B 1 641 LEU 641 641 641 LEU LEU B . n 
B 1 642 ILE 642 642 642 ILE ILE B . n 
B 1 643 ALA 643 643 643 ALA ALA B . n 
B 1 644 LEU 644 644 644 LEU LEU B . n 
B 1 645 MET 645 645 645 MET MET B . n 
B 1 646 SER 646 646 646 SER SER B . n 
B 1 647 GLU 647 647 647 GLU GLU B . n 
B 1 648 THR 648 648 648 THR THR B . n 
B 1 649 VAL 649 649 649 VAL VAL B . n 
B 1 650 ASN 650 650 650 ASN ASN B . n 
B 1 651 HIS 651 651 651 HIS HIS B . n 
B 1 652 VAL 652 652 652 VAL VAL B . n 
B 1 653 ALA 653 653 653 ALA ALA B . n 
B 1 654 ASP 654 654 654 ASP ASP B . n 
B 1 655 ASN 655 655 655 ASN ASN B . n 
B 1 656 SER 656 656 656 SER SER B . n 
B 1 657 TRP 657 657 657 TRP TRP B . n 
B 1 658 SER 658 658 658 SER SER B . n 
B 1 659 ILE 659 659 659 ILE ILE B . n 
B 1 660 TRP 660 660 660 TRP TRP B . n 
B 1 661 LYS 661 661 661 LYS LYS B . n 
B 1 662 LEU 662 662 662 LEU LEU B . n 
B 1 663 GLN 663 663 663 GLN GLN B . n 
B 1 664 LYS 664 664 664 LYS LYS B . n 
B 1 665 ALA 665 665 665 ALA ALA B . n 
B 1 666 ILE 666 666 666 ILE ILE B . n 
B 1 667 SER 667 667 667 SER SER B . n 
B 1 668 VAL 668 668 668 VAL VAL B . n 
B 1 669 LEU 669 669 669 LEU LEU B . n 
B 1 670 GLU 670 670 670 GLU GLU B . n 
B 1 671 MET 671 671 671 MET MET B . n 
B 1 672 GLU 672 672 672 GLU GLU B . n 
B 1 673 ASN 673 673 673 ASN ASN B . n 
B 1 674 GLY 674 674 674 GLY GLY B . n 
B 1 675 TYR 675 675 675 TYR TYR B . n 
B 1 676 TRP 676 676 676 TRP TRP B . n 
B 1 677 TRP 677 677 677 TRP TRP B . n 
B 1 678 CYS 678 678 678 CYS CYS B . n 
B 1 679 ARG 679 679 679 ARG ARG B . n 
B 1 680 ARG 680 680 680 ARG ARG B . n 
B 1 681 LYS 681 681 681 LYS LYS B . n 
B 1 682 LYS 682 682 682 LYS LYS B . n 
B 1 683 HIS 683 683 683 HIS HIS B . n 
B 1 684 ARG 684 684 684 ARG ARG B . n 
B 1 685 GLU 685 685 685 GLU GLU B . n 
B 1 686 GLY 686 686 686 GLY GLY B . n 
B 1 687 ARG 687 687 687 ARG ARG B . n 
B 1 688 LEU 688 688 688 LEU LEU B . n 
B 1 689 LEU 689 689 689 LEU LEU B . n 
B 1 690 LYS 690 690 690 LYS LYS B . n 
B 1 691 VAL 691 691 691 VAL VAL B . n 
B 1 692 GLY 692 692 692 GLY GLY B . n 
B 1 693 THR 693 693 693 THR THR B . n 
B 1 694 ARG 694 694 694 ARG ARG B . n 
B 1 695 GLY 695 695 ?   ?   ?   B . n 
B 1 696 ASP 696 696 ?   ?   ?   B . n 
B 1 697 GLY 697 697 ?   ?   ?   B . n 
B 1 698 THR 698 698 ?   ?   ?   B . n 
B 1 699 PRO 699 699 699 PRO PRO B . n 
B 1 700 ASP 700 700 700 ASP ASP B . n 
B 1 701 GLU 701 701 701 GLU GLU B . n 
B 1 702 ARG 702 702 702 ARG ARG B . n 
B 1 703 TRP 703 703 703 TRP TRP B . n 
B 1 704 CYS 704 704 704 CYS CYS B . n 
B 1 705 PHE 705 705 705 PHE PHE B . n 
B 1 706 ARG 706 706 706 ARG ARG B . n 
B 1 707 VAL 707 707 707 VAL VAL B . n 
B 1 708 GLU 708 708 708 GLU GLU B . n 
B 1 709 GLU 709 709 709 GLU GLU B . n 
B 1 710 VAL 710 710 710 VAL VAL B . n 
B 1 711 ASN 711 711 711 ASN ASN B . n 
B 1 712 TRP 712 712 712 TRP TRP B . n 
B 1 713 ALA 713 713 713 ALA ALA B . n 
B 1 714 ALA 714 714 714 ALA ALA B . n 
B 1 715 TRP 715 715 715 TRP TRP B . n 
B 1 716 GLU 716 716 716 GLU GLU B . n 
B 1 717 LYS 717 717 717 LYS LYS B . n 
B 1 718 THR 718 718 718 THR THR B . n 
B 1 719 LEU 719 719 719 LEU LEU B . n 
B 1 720 PRO 720 720 ?   ?   ?   B . n 
B 1 721 THR 721 721 ?   ?   ?   B . n 
B 1 722 LEU 722 722 ?   ?   ?   B . n 
B 1 723 SER 723 723 ?   ?   ?   B . n 
B 1 724 ALA 724 724 ?   ?   ?   B . n 
B 1 725 ALA 725 725 ?   ?   ?   B . n 
B 1 726 PRO 726 726 ?   ?   ?   B . n 
B 1 727 SER 727 727 ?   ?   ?   B . n 
B 1 728 GLY 728 728 ?   ?   ?   B . n 
B 1 729 PRO 729 729 ?   ?   ?   B . n 
B 1 730 GLY 730 730 ?   ?   ?   B . n 
B 1 731 ILE 731 731 ?   ?   ?   B . n 
B 1 732 THR 732 732 ?   ?   ?   B . n 
B 1 733 GLY 733 733 ?   ?   ?   B . n 
B 1 734 ASN 734 734 ?   ?   ?   B . n 
B 1 735 LYS 735 735 ?   ?   ?   B . n 
B 1 736 LYS 736 736 ?   ?   ?   B . n 
B 1 737 ASN 737 737 ?   ?   ?   B . n 
B 1 738 PRO 738 738 ?   ?   ?   B . n 
B 1 739 THR 739 739 ?   ?   ?   B . n 
B 1 740 SER 740 740 ?   ?   ?   B . n 
B 1 741 LYS 741 741 ?   ?   ?   B . n 
B 1 742 PRO 742 742 ?   ?   ?   B . n 
B 1 743 GLY 743 743 ?   ?   ?   B . n 
B 1 744 LYS 744 744 ?   ?   ?   B . n 
B 1 745 ASN 745 745 ?   ?   ?   B . n 
B 1 746 SER 746 746 ?   ?   ?   B . n 
B 1 747 ALA 747 747 ?   ?   ?   B . n 
B 1 748 SER 748 748 ?   ?   ?   B . n 
B 1 749 GLU 749 749 ?   ?   ?   B . n 
B 1 750 GLU 750 750 ?   ?   ?   B . n 
B 1 751 ASP 751 751 ?   ?   ?   B . n 
B 1 752 HIS 752 752 ?   ?   ?   B . n 
B 1 753 LEU 753 753 ?   ?   ?   B . n 
B 1 754 PRO 754 754 ?   ?   ?   B . n 
B 1 755 LEU 755 755 ?   ?   ?   B . n 
B 1 756 GLN 756 756 ?   ?   ?   B . n 
B 1 757 VAL 757 757 ?   ?   ?   B . n 
B 1 758 LEU 758 758 ?   ?   ?   B . n 
B 1 759 GLN 759 759 ?   ?   ?   B . n 
B 1 760 SER 760 760 ?   ?   ?   B . n 
B 1 761 PRO 761 761 ?   ?   ?   B . n 
C 1 1   MET 1   1   ?   ?   ?   C . n 
C 1 2   THR 2   2   ?   ?   ?   C . n 
C 1 3   SER 3   3   ?   ?   ?   C . n 
C 1 4   ALA 4   4   ?   ?   ?   C . n 
C 1 5   SER 5   5   ?   ?   ?   C . n 
C 1 6   SER 6   6   ?   ?   ?   C . n 
C 1 7   PRO 7   7   ?   ?   ?   C . n 
C 1 8   PRO 8   8   ?   ?   ?   C . n 
C 1 9   ALA 9   9   ?   ?   ?   C . n 
C 1 10  PHE 10  10  ?   ?   ?   C . n 
C 1 11  ARG 11  11  ?   ?   ?   C . n 
C 1 12  LEU 12  12  ?   ?   ?   C . n 
C 1 13  GLU 13  13  ?   ?   ?   C . n 
C 1 14  THR 14  14  ?   ?   ?   C . n 
C 1 15  SER 15  15  ?   ?   ?   C . n 
C 1 16  ASP 16  16  ?   ?   ?   C . n 
C 1 17  GLY 17  17  ?   ?   ?   C . n 
C 1 18  ASP 18  18  ?   ?   ?   C . n 
C 1 19  GLU 19  19  ?   ?   ?   C . n 
C 1 20  GLU 20  20  ?   ?   ?   C . n 
C 1 21  GLY 21  21  ?   ?   ?   C . n 
C 1 22  ASN 22  22  ?   ?   ?   C . n 
C 1 23  ALA 23  23  ?   ?   ?   C . n 
C 1 24  GLU 24  24  ?   ?   ?   C . n 
C 1 25  VAL 25  25  ?   ?   ?   C . n 
C 1 26  ASN 26  26  ?   ?   ?   C . n 
C 1 27  LYS 27  27  ?   ?   ?   C . n 
C 1 28  GLY 28  28  ?   ?   ?   C . n 
C 1 29  LYS 29  29  ?   ?   ?   C . n 
C 1 30  GLN 30  30  ?   ?   ?   C . n 
C 1 31  GLU 31  31  ?   ?   ?   C . n 
C 1 32  PRO 32  32  ?   ?   ?   C . n 
C 1 33  PRO 33  33  ?   ?   ?   C . n 
C 1 34  PRO 34  34  ?   ?   ?   C . n 
C 1 35  MET 35  35  ?   ?   ?   C . n 
C 1 36  GLU 36  36  ?   ?   ?   C . n 
C 1 37  SER 37  37  ?   ?   ?   C . n 
C 1 38  PRO 38  38  ?   ?   ?   C . n 
C 1 39  PHE 39  39  ?   ?   ?   C . n 
C 1 40  GLN 40  40  ?   ?   ?   C . n 
C 1 41  ARG 41  41  ?   ?   ?   C . n 
C 1 42  GLU 42  42  ?   ?   ?   C . n 
C 1 43  ASP 43  43  ?   ?   ?   C . n 
C 1 44  ARG 44  44  ?   ?   ?   C . n 
C 1 45  ASN 45  45  ?   ?   ?   C . n 
C 1 46  SER 46  46  ?   ?   ?   C . n 
C 1 47  SER 47  47  ?   ?   ?   C . n 
C 1 48  PRO 48  48  ?   ?   ?   C . n 
C 1 49  GLN 49  49  ?   ?   ?   C . n 
C 1 50  ILE 50  50  ?   ?   ?   C . n 
C 1 51  LYS 51  51  ?   ?   ?   C . n 
C 1 52  VAL 52  52  ?   ?   ?   C . n 
C 1 53  ASN 53  53  ?   ?   ?   C . n 
C 1 54  LEU 54  54  ?   ?   ?   C . n 
C 1 55  ASN 55  55  ?   ?   ?   C . n 
C 1 56  PHE 56  56  ?   ?   ?   C . n 
C 1 57  ILE 57  57  ?   ?   ?   C . n 
C 1 58  LYS 58  58  ?   ?   ?   C . n 
C 1 59  ARG 59  59  ?   ?   ?   C . n 
C 1 60  PRO 60  60  ?   ?   ?   C . n 
C 1 61  PRO 61  61  ?   ?   ?   C . n 
C 1 62  LYS 62  62  ?   ?   ?   C . n 
C 1 63  ASN 63  63  ?   ?   ?   C . n 
C 1 64  THR 64  64  ?   ?   ?   C . n 
C 1 65  SER 65  65  ?   ?   ?   C . n 
C 1 66  ALA 66  66  ?   ?   ?   C . n 
C 1 67  PRO 67  67  ?   ?   ?   C . n 
C 1 68  SER 68  68  ?   ?   ?   C . n 
C 1 69  GLN 69  69  ?   ?   ?   C . n 
C 1 70  GLN 70  70  ?   ?   ?   C . n 
C 1 71  GLU 71  71  ?   ?   ?   C . n 
C 1 72  PRO 72  72  ?   ?   ?   C . n 
C 1 73  ASP 73  73  ?   ?   ?   C . n 
C 1 74  ARG 74  74  74  ARG ARG C . n 
C 1 75  PHE 75  75  75  PHE PHE C . n 
C 1 76  ASP 76  76  76  ASP ASP C . n 
C 1 77  ARG 77  77  77  ARG ARG C . n 
C 1 78  ASP 78  78  78  ASP ASP C . n 
C 1 79  ARG 79  79  79  ARG ARG C . n 
C 1 80  LEU 80  80  80  LEU LEU C . n 
C 1 81  PHE 81  81  81  PHE PHE C . n 
C 1 82  SER 82  82  82  SER SER C . n 
C 1 83  VAL 83  83  83  VAL VAL C . n 
C 1 84  VAL 84  84  84  VAL VAL C . n 
C 1 85  SER 85  85  85  SER SER C . n 
C 1 86  ARG 86  86  86  ARG ARG C . n 
C 1 87  GLY 87  87  87  GLY GLY C . n 
C 1 88  VAL 88  88  88  VAL VAL C . n 
C 1 89  PRO 89  89  89  PRO PRO C . n 
C 1 90  GLU 90  90  90  GLU GLU C . n 
C 1 91  GLU 91  91  91  GLU GLU C . n 
C 1 92  LEU 92  92  92  LEU LEU C . n 
C 1 93  THR 93  93  93  THR THR C . n 
C 1 94  GLY 94  94  94  GLY GLY C . n 
C 1 95  LEU 95  95  95  LEU LEU C . n 
C 1 96  LEU 96  96  96  LEU LEU C . n 
C 1 97  GLU 97  97  97  GLU GLU C . n 
C 1 98  TYR 98  98  98  TYR TYR C . n 
C 1 99  LEU 99  99  99  LEU LEU C . n 
C 1 100 ARG 100 100 100 ARG ARG C . n 
C 1 101 TRP 101 101 101 TRP TRP C . n 
C 1 102 ASN 102 102 102 ASN ASN C . n 
C 1 103 SER 103 103 103 SER SER C . n 
C 1 104 LYS 104 104 104 LYS LYS C . n 
C 1 105 TYR 105 105 105 TYR TYR C . n 
C 1 106 LEU 106 106 106 LEU LEU C . n 
C 1 107 THR 107 107 107 THR THR C . n 
C 1 108 ASP 108 108 108 ASP ASP C . n 
C 1 109 SER 109 109 109 SER SER C . n 
C 1 110 ALA 110 110 110 ALA ALA C . n 
C 1 111 TYR 111 111 111 TYR TYR C . n 
C 1 112 THR 112 112 112 THR THR C . n 
C 1 113 GLU 113 113 113 GLU GLU C . n 
C 1 114 GLY 114 114 114 GLY GLY C . n 
C 1 115 SER 115 115 115 SER SER C . n 
C 1 116 THR 116 116 116 THR THR C . n 
C 1 117 GLY 117 117 117 GLY GLY C . n 
C 1 118 LYS 118 118 118 LYS LYS C . n 
C 1 119 THR 119 119 119 THR THR C . n 
C 1 120 CYS 120 120 120 CYS CYS C . n 
C 1 121 LEU 121 121 121 LEU LEU C . n 
C 1 122 MET 122 122 122 MET MET C . n 
C 1 123 LYS 123 123 123 LYS LYS C . n 
C 1 124 ALA 124 124 124 ALA ALA C . n 
C 1 125 VAL 125 125 125 VAL VAL C . n 
C 1 126 LEU 126 126 126 LEU LEU C . n 
C 1 127 ASN 127 127 127 ASN ASN C . n 
C 1 128 LEU 128 128 128 LEU LEU C . n 
C 1 129 GLN 129 129 129 GLN GLN C . n 
C 1 130 ASP 130 130 130 ASP ASP C . n 
C 1 131 GLY 131 131 131 GLY GLY C . n 
C 1 132 VAL 132 132 132 VAL VAL C . n 
C 1 133 ASN 133 133 133 ASN ASN C . n 
C 1 134 ALA 134 134 134 ALA ALA C . n 
C 1 135 CYS 135 135 135 CYS CYS C . n 
C 1 136 ILE 136 136 136 ILE ILE C . n 
C 1 137 MET 137 137 137 MET MET C . n 
C 1 138 PRO 138 138 138 PRO PRO C . n 
C 1 139 LEU 139 139 139 LEU LEU C . n 
C 1 140 LEU 140 140 140 LEU LEU C . n 
C 1 141 GLN 141 141 141 GLN GLN C . n 
C 1 142 ILE 142 142 142 ILE ILE C . n 
C 1 143 ASP 143 143 143 ASP ASP C . n 
C 1 144 LYS 144 144 144 LYS LYS C . n 
C 1 145 ASP 145 145 145 ASP ASP C . n 
C 1 146 SER 146 146 146 SER SER C . n 
C 1 147 GLY 147 147 147 GLY GLY C . n 
C 1 148 ASN 148 148 148 ASN ASN C . n 
C 1 149 PRO 149 149 149 PRO PRO C . n 
C 1 150 LYS 150 150 150 LYS LYS C . n 
C 1 151 LEU 151 151 151 LEU LEU C . n 
C 1 152 LEU 152 152 152 LEU LEU C . n 
C 1 153 VAL 153 153 153 VAL VAL C . n 
C 1 154 ASN 154 154 154 ASN ASN C . n 
C 1 155 ALA 155 155 155 ALA ALA C . n 
C 1 156 GLN 156 156 156 GLN GLN C . n 
C 1 157 CYS 157 157 157 CYS CYS C . n 
C 1 158 THR 158 158 158 THR THR C . n 
C 1 159 ASP 159 159 159 ASP ASP C . n 
C 1 160 GLU 160 160 160 GLU GLU C . n 
C 1 161 PHE 161 161 161 PHE PHE C . n 
C 1 162 TYR 162 162 162 TYR TYR C . n 
C 1 163 GLN 163 163 163 GLN GLN C . n 
C 1 164 GLY 164 164 164 GLY GLY C . n 
C 1 165 HIS 165 165 165 HIS HIS C . n 
C 1 166 SER 166 166 166 SER SER C . n 
C 1 167 ALA 167 167 167 ALA ALA C . n 
C 1 168 LEU 168 168 168 LEU LEU C . n 
C 1 169 HIS 169 169 169 HIS HIS C . n 
C 1 170 ILE 170 170 170 ILE ILE C . n 
C 1 171 ALA 171 171 171 ALA ALA C . n 
C 1 172 ILE 172 172 172 ILE ILE C . n 
C 1 173 GLU 173 173 173 GLU GLU C . n 
C 1 174 LYS 174 174 174 LYS LYS C . n 
C 1 175 ARG 175 175 175 ARG ARG C . n 
C 1 176 SER 176 176 176 SER SER C . n 
C 1 177 LEU 177 177 177 LEU LEU C . n 
C 1 178 GLN 178 178 178 GLN GLN C . n 
C 1 179 CYS 179 179 179 CYS CYS C . n 
C 1 180 VAL 180 180 180 VAL VAL C . n 
C 1 181 LYS 181 181 181 LYS LYS C . n 
C 1 182 LEU 182 182 182 LEU LEU C . n 
C 1 183 LEU 183 183 183 LEU LEU C . n 
C 1 184 VAL 184 184 184 VAL VAL C . n 
C 1 185 GLU 185 185 185 GLU GLU C . n 
C 1 186 ASN 186 186 186 ASN ASN C . n 
C 1 187 GLY 187 187 187 GLY GLY C . n 
C 1 188 ALA 188 188 188 ALA ALA C . n 
C 1 189 ASP 189 189 189 ASP ASP C . n 
C 1 190 VAL 190 190 190 VAL VAL C . n 
C 1 191 HIS 191 191 191 HIS HIS C . n 
C 1 192 LEU 192 192 192 LEU LEU C . n 
C 1 193 ARG 193 193 193 ARG ARG C . n 
C 1 194 ALA 194 194 194 ALA ALA C . n 
C 1 195 CYS 195 195 195 CYS CYS C . n 
C 1 196 GLY 196 196 196 GLY GLY C . n 
C 1 197 ARG 197 197 197 ARG ARG C . n 
C 1 198 PHE 198 198 198 PHE PHE C . n 
C 1 199 PHE 199 199 199 PHE PHE C . n 
C 1 200 GLN 200 200 200 GLN GLN C . n 
C 1 201 LYS 201 201 201 LYS LYS C . n 
C 1 202 HIS 202 202 202 HIS HIS C . n 
C 1 203 GLN 203 203 203 GLN GLN C . n 
C 1 204 GLY 204 204 204 GLY GLY C . n 
C 1 205 THR 205 205 205 THR THR C . n 
C 1 206 CYS 206 206 206 CYS CYS C . n 
C 1 207 PHE 207 207 207 PHE PHE C . n 
C 1 208 TYR 208 208 208 TYR TYR C . n 
C 1 209 PHE 209 209 209 PHE PHE C . n 
C 1 210 GLY 210 210 210 GLY GLY C . n 
C 1 211 GLU 211 211 211 GLU GLU C . n 
C 1 212 LEU 212 212 212 LEU LEU C . n 
C 1 213 PRO 213 213 213 PRO PRO C . n 
C 1 214 LEU 214 214 214 LEU LEU C . n 
C 1 215 SER 215 215 215 SER SER C . n 
C 1 216 LEU 216 216 216 LEU LEU C . n 
C 1 217 ALA 217 217 217 ALA ALA C . n 
C 1 218 ALA 218 218 218 ALA ALA C . n 
C 1 219 CYS 219 219 219 CYS CYS C . n 
C 1 220 THR 220 220 220 THR THR C . n 
C 1 221 LYS 221 221 221 LYS LYS C . n 
C 1 222 GLN 222 222 222 GLN GLN C . n 
C 1 223 TRP 223 223 223 TRP TRP C . n 
C 1 224 ASP 224 224 224 ASP ASP C . n 
C 1 225 VAL 225 225 225 VAL VAL C . n 
C 1 226 VAL 226 226 226 VAL VAL C . n 
C 1 227 THR 227 227 227 THR THR C . n 
C 1 228 TYR 228 228 228 TYR TYR C . n 
C 1 229 LEU 229 229 229 LEU LEU C . n 
C 1 230 LEU 230 230 230 LEU LEU C . n 
C 1 231 GLU 231 231 231 GLU GLU C . n 
C 1 232 ASN 232 232 232 ASN ASN C . n 
C 1 233 PRO 233 233 233 PRO PRO C . n 
C 1 234 HIS 234 234 234 HIS HIS C . n 
C 1 235 GLN 235 235 235 GLN GLN C . n 
C 1 236 PRO 236 236 236 PRO PRO C . n 
C 1 237 ALA 237 237 237 ALA ALA C . n 
C 1 238 SER 238 238 238 SER SER C . n 
C 1 239 LEU 239 239 239 LEU LEU C . n 
C 1 240 GLU 240 240 240 GLU GLU C . n 
C 1 241 ALA 241 241 241 ALA ALA C . n 
C 1 242 THR 242 242 242 THR THR C . n 
C 1 243 ASP 243 243 243 ASP ASP C . n 
C 1 244 SER 244 244 244 SER SER C . n 
C 1 245 LEU 245 245 245 LEU LEU C . n 
C 1 246 GLY 246 246 246 GLY GLY C . n 
C 1 247 ASN 247 247 247 ASN ASN C . n 
C 1 248 THR 248 248 248 THR THR C . n 
C 1 249 VAL 249 249 249 VAL VAL C . n 
C 1 250 LEU 250 250 250 LEU LEU C . n 
C 1 251 HIS 251 251 251 HIS HIS C . n 
C 1 252 ALA 252 252 252 ALA ALA C . n 
C 1 253 LEU 253 253 253 LEU LEU C . n 
C 1 254 VAL 254 254 254 VAL VAL C . n 
C 1 255 MET 255 255 255 MET MET C . n 
C 1 256 ILE 256 256 256 ILE ILE C . n 
C 1 257 ALA 257 257 257 ALA ALA C . n 
C 1 258 ASP 258 258 258 ASP ASP C . n 
C 1 259 ASN 259 259 259 ASN ASN C . n 
C 1 260 SER 260 260 260 SER SER C . n 
C 1 261 PRO 261 261 261 PRO PRO C . n 
C 1 262 GLU 262 262 262 GLU GLU C . n 
C 1 263 ASN 263 263 263 ASN ASN C . n 
C 1 264 SER 264 264 264 SER SER C . n 
C 1 265 ALA 265 265 265 ALA ALA C . n 
C 1 266 LEU 266 266 266 LEU LEU C . n 
C 1 267 VAL 267 267 267 VAL VAL C . n 
C 1 268 ILE 268 268 268 ILE ILE C . n 
C 1 269 HIS 269 269 269 HIS HIS C . n 
C 1 270 MET 270 270 270 MET MET C . n 
C 1 271 TYR 271 271 271 TYR TYR C . n 
C 1 272 ASP 272 272 272 ASP ASP C . n 
C 1 273 GLY 273 273 273 GLY GLY C . n 
C 1 274 LEU 274 274 274 LEU LEU C . n 
C 1 275 LEU 275 275 275 LEU LEU C . n 
C 1 276 GLN 276 276 276 GLN GLN C . n 
C 1 277 MET 277 277 277 MET MET C . n 
C 1 278 GLY 278 278 278 GLY GLY C . n 
C 1 279 ALA 279 279 279 ALA ALA C . n 
C 1 280 ARG 280 280 280 ARG ARG C . n 
C 1 281 LEU 281 281 281 LEU LEU C . n 
C 1 282 CYS 282 282 282 CYS CYS C . n 
C 1 283 PRO 283 283 283 PRO PRO C . n 
C 1 284 THR 284 284 284 THR THR C . n 
C 1 285 VAL 285 285 285 VAL VAL C . n 
C 1 286 GLN 286 286 286 GLN GLN C . n 
C 1 287 LEU 287 287 287 LEU LEU C . n 
C 1 288 GLU 288 288 288 GLU GLU C . n 
C 1 289 GLU 289 289 289 GLU GLU C . n 
C 1 290 ILE 290 290 290 ILE ILE C . n 
C 1 291 SER 291 291 291 SER SER C . n 
C 1 292 ASN 292 292 292 ASN ASN C . n 
C 1 293 HIS 293 293 293 HIS HIS C . n 
C 1 294 GLN 294 294 294 GLN GLN C . n 
C 1 295 GLY 295 295 295 GLY GLY C . n 
C 1 296 LEU 296 296 296 LEU LEU C . n 
C 1 297 THR 297 297 297 THR THR C . n 
C 1 298 PRO 298 298 298 PRO PRO C . n 
C 1 299 LEU 299 299 299 LEU LEU C . n 
C 1 300 LYS 300 300 300 LYS LYS C . n 
C 1 301 LEU 301 301 301 LEU LEU C . n 
C 1 302 ALA 302 302 302 ALA ALA C . n 
C 1 303 ALA 303 303 303 ALA ALA C . n 
C 1 304 LYS 304 304 304 LYS LYS C . n 
C 1 305 GLU 305 305 305 GLU GLU C . n 
C 1 306 GLY 306 306 306 GLY GLY C . n 
C 1 307 LYS 307 307 307 LYS LYS C . n 
C 1 308 ILE 308 308 308 ILE ILE C . n 
C 1 309 GLU 309 309 309 GLU GLU C . n 
C 1 310 ILE 310 310 310 ILE ILE C . n 
C 1 311 PHE 311 311 311 PHE PHE C . n 
C 1 312 ARG 312 312 312 ARG ARG C . n 
C 1 313 HIS 313 313 313 HIS HIS C . n 
C 1 314 ILE 314 314 314 ILE ILE C . n 
C 1 315 LEU 315 315 315 LEU LEU C . n 
C 1 316 GLN 316 316 316 GLN GLN C . n 
C 1 317 ARG 317 317 317 ARG ARG C . n 
C 1 318 GLU 318 318 318 GLU GLU C . n 
C 1 319 PHE 319 319 319 PHE PHE C . n 
C 1 320 SER 320 320 320 SER SER C . n 
C 1 321 GLY 321 321 321 GLY GLY C . n 
C 1 322 PRO 322 322 322 PRO PRO C . n 
C 1 323 TYR 323 323 323 TYR TYR C . n 
C 1 324 GLN 324 324 324 GLN GLN C . n 
C 1 325 PRO 325 325 325 PRO PRO C . n 
C 1 326 LEU 326 326 326 LEU LEU C . n 
C 1 327 SER 327 327 327 SER SER C . n 
C 1 328 ARG 328 328 328 ARG ARG C . n 
C 1 329 LYS 329 329 329 LYS LYS C . n 
C 1 330 PHE 330 330 330 PHE PHE C . n 
C 1 331 THR 331 331 331 THR THR C . n 
C 1 332 GLU 332 332 332 GLU GLU C . n 
C 1 333 TRP 333 333 333 TRP TRP C . n 
C 1 334 CYS 334 334 334 CYS CYS C . n 
C 1 335 TYR 335 335 335 TYR TYR C . n 
C 1 336 GLY 336 336 336 GLY GLY C . n 
C 1 337 PRO 337 337 337 PRO PRO C . n 
C 1 338 VAL 338 338 338 VAL VAL C . n 
C 1 339 ARG 339 339 339 ARG ARG C . n 
C 1 340 VAL 340 340 340 VAL VAL C . n 
C 1 341 SER 341 341 341 SER SER C . n 
C 1 342 LEU 342 342 342 LEU LEU C . n 
C 1 343 TYR 343 343 343 TYR TYR C . n 
C 1 344 ASP 344 344 344 ASP ASP C . n 
C 1 345 LEU 345 345 345 LEU LEU C . n 
C 1 346 SER 346 346 346 SER SER C . n 
C 1 347 SER 347 347 347 SER SER C . n 
C 1 348 VAL 348 348 348 VAL VAL C . n 
C 1 349 ASP 349 349 349 ASP ASP C . n 
C 1 350 SER 350 350 350 SER SER C . n 
C 1 351 TRP 351 351 351 TRP TRP C . n 
C 1 352 GLU 352 352 352 GLU GLU C . n 
C 1 353 LYS 353 353 353 LYS LYS C . n 
C 1 354 ASN 354 354 354 ASN ASN C . n 
C 1 355 SER 355 355 355 SER SER C . n 
C 1 356 VAL 356 356 356 VAL VAL C . n 
C 1 357 LEU 357 357 357 LEU LEU C . n 
C 1 358 GLU 358 358 358 GLU GLU C . n 
C 1 359 ILE 359 359 359 ILE ILE C . n 
C 1 360 ILE 360 360 360 ILE ILE C . n 
C 1 361 ALA 361 361 361 ALA ALA C . n 
C 1 362 PHE 362 362 362 PHE PHE C . n 
C 1 363 HIS 363 363 363 HIS HIS C . n 
C 1 364 CYS 364 364 364 CYS CYS C . n 
C 1 365 LYS 365 365 365 LYS LYS C . n 
C 1 366 SER 366 366 366 SER SER C . n 
C 1 367 PRO 367 367 367 PRO PRO C . n 
C 1 368 ASN 368 368 368 ASN ASN C . n 
C 1 369 ARG 369 369 369 ARG ARG C . n 
C 1 370 HIS 370 370 370 HIS HIS C . n 
C 1 371 ARG 371 371 371 ARG ARG C . n 
C 1 372 MET 372 372 372 MET MET C . n 
C 1 373 VAL 373 373 373 VAL VAL C . n 
C 1 374 VAL 374 374 374 VAL VAL C . n 
C 1 375 LEU 375 375 375 LEU LEU C . n 
C 1 376 GLU 376 376 376 GLU GLU C . n 
C 1 377 PRO 377 377 377 PRO PRO C . n 
C 1 378 LEU 378 378 378 LEU LEU C . n 
C 1 379 ASN 379 379 379 ASN ASN C . n 
C 1 380 LYS 380 380 380 LYS LYS C . n 
C 1 381 LEU 381 381 381 LEU LEU C . n 
C 1 382 LEU 382 382 382 LEU LEU C . n 
C 1 383 GLN 383 383 383 GLN GLN C . n 
C 1 384 GLU 384 384 384 GLU GLU C . n 
C 1 385 LYS 385 385 385 LYS LYS C . n 
C 1 386 TRP 386 386 386 TRP TRP C . n 
C 1 387 ASP 387 387 387 ASP ASP C . n 
C 1 388 ARG 388 388 388 ARG ARG C . n 
C 1 389 LEU 389 389 389 LEU LEU C . n 
C 1 390 VAL 390 390 390 VAL VAL C . n 
C 1 391 SER 391 391 391 SER SER C . n 
C 1 392 ARG 392 392 392 ARG ARG C . n 
C 1 393 PHE 393 393 393 PHE PHE C . n 
C 1 394 PHE 394 394 394 PHE PHE C . n 
C 1 395 PHE 395 395 395 PHE PHE C . n 
C 1 396 ASN 396 396 396 ASN ASN C . n 
C 1 397 PHE 397 397 397 PHE PHE C . n 
C 1 398 ALA 398 398 398 ALA ALA C . n 
C 1 399 CYS 399 399 399 CYS CYS C . n 
C 1 400 TYR 400 400 400 TYR TYR C . n 
C 1 401 LEU 401 401 401 LEU LEU C . n 
C 1 402 VAL 402 402 402 VAL VAL C . n 
C 1 403 TYR 403 403 403 TYR TYR C . n 
C 1 404 MET 404 404 404 MET MET C . n 
C 1 405 PHE 405 405 405 PHE PHE C . n 
C 1 406 ILE 406 406 406 ILE ILE C . n 
C 1 407 PHE 407 407 407 PHE PHE C . n 
C 1 408 THR 408 408 408 THR THR C . n 
C 1 409 VAL 409 409 409 VAL VAL C . n 
C 1 410 VAL 410 410 410 VAL VAL C . n 
C 1 411 ALA 411 411 411 ALA ALA C . n 
C 1 412 TYR 412 412 412 TYR TYR C . n 
C 1 413 HIS 413 413 413 HIS HIS C . n 
C 1 414 GLN 414 414 414 GLN GLN C . n 
C 1 415 PRO 415 415 415 PRO PRO C . n 
C 1 416 SER 416 416 416 SER SER C . n 
C 1 417 LEU 417 417 417 LEU LEU C . n 
C 1 418 ASP 418 418 ?   ?   ?   C . n 
C 1 419 GLN 419 419 ?   ?   ?   C . n 
C 1 420 PRO 420 420 ?   ?   ?   C . n 
C 1 421 ALA 421 421 ?   ?   ?   C . n 
C 1 422 ILE 422 422 ?   ?   ?   C . n 
C 1 423 PRO 423 423 ?   ?   ?   C . n 
C 1 424 SER 424 424 ?   ?   ?   C . n 
C 1 425 SER 425 425 ?   ?   ?   C . n 
C 1 426 LYS 426 426 ?   ?   ?   C . n 
C 1 427 ALA 427 427 ?   ?   ?   C . n 
C 1 428 THR 428 428 ?   ?   ?   C . n 
C 1 429 PHE 429 429 429 PHE PHE C . n 
C 1 430 GLY 430 430 430 GLY GLY C . n 
C 1 431 GLU 431 431 431 GLU GLU C . n 
C 1 432 SER 432 432 432 SER SER C . n 
C 1 433 MET 433 433 433 MET MET C . n 
C 1 434 LEU 434 434 434 LEU LEU C . n 
C 1 435 LEU 435 435 435 LEU LEU C . n 
C 1 436 LEU 436 436 436 LEU LEU C . n 
C 1 437 GLY 437 437 437 GLY GLY C . n 
C 1 438 HIS 438 438 438 HIS HIS C . n 
C 1 439 ILE 439 439 439 ILE ILE C . n 
C 1 440 LEU 440 440 440 LEU LEU C . n 
C 1 441 ILE 441 441 441 ILE ILE C . n 
C 1 442 LEU 442 442 442 LEU LEU C . n 
C 1 443 LEU 443 443 443 LEU LEU C . n 
C 1 444 GLY 444 444 444 GLY GLY C . n 
C 1 445 GLY 445 445 445 GLY GLY C . n 
C 1 446 ILE 446 446 446 ILE ILE C . n 
C 1 447 TYR 447 447 447 TYR TYR C . n 
C 1 448 LEU 448 448 448 LEU LEU C . n 
C 1 449 LEU 449 449 449 LEU LEU C . n 
C 1 450 LEU 450 450 450 LEU LEU C . n 
C 1 451 GLY 451 451 451 GLY GLY C . n 
C 1 452 GLN 452 452 452 GLN GLN C . n 
C 1 453 LEU 453 453 453 LEU LEU C . n 
C 1 454 TRP 454 454 454 TRP TRP C . n 
C 1 455 TYR 455 455 455 TYR TYR C . n 
C 1 456 PHE 456 456 456 PHE PHE C . n 
C 1 457 TRP 457 457 457 TRP TRP C . n 
C 1 458 ARG 458 458 458 ARG ARG C . n 
C 1 459 ARG 459 459 459 ARG ARG C . n 
C 1 460 ARG 460 460 460 ARG ARG C . n 
C 1 461 LEU 461 461 461 LEU LEU C . n 
C 1 462 PHE 462 462 462 PHE PHE C . n 
C 1 463 ILE 463 463 463 ILE ILE C . n 
C 1 464 TRP 464 464 464 TRP TRP C . n 
C 1 465 ILE 465 465 465 ILE ILE C . n 
C 1 466 SER 466 466 466 SER SER C . n 
C 1 467 PHE 467 467 467 PHE PHE C . n 
C 1 468 MET 468 468 468 MET MET C . n 
C 1 469 ASP 469 469 469 ASP ASP C . n 
C 1 470 SER 470 470 470 SER SER C . n 
C 1 471 TYR 471 471 471 TYR TYR C . n 
C 1 472 PHE 472 472 472 PHE PHE C . n 
C 1 473 GLU 473 473 473 GLU GLU C . n 
C 1 474 ILE 474 474 474 ILE ILE C . n 
C 1 475 LEU 475 475 475 LEU LEU C . n 
C 1 476 PHE 476 476 476 PHE PHE C . n 
C 1 477 LEU 477 477 477 LEU LEU C . n 
C 1 478 LEU 478 478 478 LEU LEU C . n 
C 1 479 GLN 479 479 479 GLN GLN C . n 
C 1 480 ALA 480 480 480 ALA ALA C . n 
C 1 481 LEU 481 481 481 LEU LEU C . n 
C 1 482 LEU 482 482 482 LEU LEU C . n 
C 1 483 THR 483 483 483 THR THR C . n 
C 1 484 VAL 484 484 484 VAL VAL C . n 
C 1 485 LEU 485 485 485 LEU LEU C . n 
C 1 486 SER 486 486 486 SER SER C . n 
C 1 487 GLN 487 487 487 GLN GLN C . n 
C 1 488 VAL 488 488 488 VAL VAL C . n 
C 1 489 LEU 489 489 489 LEU LEU C . n 
C 1 490 ARG 490 490 490 ARG ARG C . n 
C 1 491 PHE 491 491 491 PHE PHE C . n 
C 1 492 MET 492 492 492 MET MET C . n 
C 1 493 GLU 493 493 493 GLU GLU C . n 
C 1 494 THR 494 494 494 THR THR C . n 
C 1 495 GLU 495 495 495 GLU GLU C . n 
C 1 496 TRP 496 496 496 TRP TRP C . n 
C 1 497 TYR 497 497 497 TYR TYR C . n 
C 1 498 LEU 498 498 498 LEU LEU C . n 
C 1 499 PRO 499 499 499 PRO PRO C . n 
C 1 500 LEU 500 500 500 LEU LEU C . n 
C 1 501 LEU 501 501 501 LEU LEU C . n 
C 1 502 VAL 502 502 502 VAL VAL C . n 
C 1 503 LEU 503 503 503 LEU LEU C . n 
C 1 504 SER 504 504 504 SER SER C . n 
C 1 505 LEU 505 505 505 LEU LEU C . n 
C 1 506 VAL 506 506 506 VAL VAL C . n 
C 1 507 LEU 507 507 507 LEU LEU C . n 
C 1 508 GLY 508 508 508 GLY GLY C . n 
C 1 509 TRP 509 509 509 TRP TRP C . n 
C 1 510 LEU 510 510 510 LEU LEU C . n 
C 1 511 ASN 511 511 511 ASN ASN C . n 
C 1 512 LEU 512 512 512 LEU LEU C . n 
C 1 513 LEU 513 513 513 LEU LEU C . n 
C 1 514 TYR 514 514 514 TYR TYR C . n 
C 1 515 TYR 515 515 515 TYR TYR C . n 
C 1 516 THR 516 516 516 THR THR C . n 
C 1 517 ARG 517 517 517 ARG ARG C . n 
C 1 518 GLY 518 518 518 GLY GLY C . n 
C 1 519 PHE 519 519 519 PHE PHE C . n 
C 1 520 GLN 520 520 520 GLN GLN C . n 
C 1 521 HIS 521 521 521 HIS HIS C . n 
C 1 522 THR 522 522 522 THR THR C . n 
C 1 523 GLY 523 523 523 GLY GLY C . n 
C 1 524 ILE 524 524 524 ILE ILE C . n 
C 1 525 TYR 525 525 525 TYR TYR C . n 
C 1 526 SER 526 526 526 SER SER C . n 
C 1 527 VAL 527 527 527 VAL VAL C . n 
C 1 528 MET 528 528 528 MET MET C . n 
C 1 529 ILE 529 529 529 ILE ILE C . n 
C 1 530 GLN 530 530 530 GLN GLN C . n 
C 1 531 LYS 531 531 531 LYS LYS C . n 
C 1 532 VAL 532 532 532 VAL VAL C . n 
C 1 533 ILE 533 533 533 ILE ILE C . n 
C 1 534 LEU 534 534 534 LEU LEU C . n 
C 1 535 ARG 535 535 535 ARG ARG C . n 
C 1 536 ASP 536 536 536 ASP ASP C . n 
C 1 537 LEU 537 537 537 LEU LEU C . n 
C 1 538 LEU 538 538 538 LEU LEU C . n 
C 1 539 ARG 539 539 539 ARG ARG C . n 
C 1 540 PHE 540 540 540 PHE PHE C . n 
C 1 541 LEU 541 541 541 LEU LEU C . n 
C 1 542 LEU 542 542 542 LEU LEU C . n 
C 1 543 VAL 543 543 543 VAL VAL C . n 
C 1 544 TYR 544 544 544 TYR TYR C . n 
C 1 545 LEU 545 545 545 LEU LEU C . n 
C 1 546 VAL 546 546 546 VAL VAL C . n 
C 1 547 PHE 547 547 547 PHE PHE C . n 
C 1 548 LEU 548 548 548 LEU LEU C . n 
C 1 549 PHE 549 549 549 PHE PHE C . n 
C 1 550 GLY 550 550 550 GLY GLY C . n 
C 1 551 PHE 551 551 551 PHE PHE C . n 
C 1 552 ALA 552 552 552 ALA ALA C . n 
C 1 553 VAL 553 553 553 VAL VAL C . n 
C 1 554 ALA 554 554 554 ALA ALA C . n 
C 1 555 LEU 555 555 555 LEU LEU C . n 
C 1 556 VAL 556 556 556 VAL VAL C . n 
C 1 557 SER 557 557 557 SER SER C . n 
C 1 558 LEU 558 558 558 LEU LEU C . n 
C 1 559 SER 559 559 559 SER SER C . n 
C 1 560 ARG 560 560 560 ARG ARG C . n 
C 1 561 GLU 561 561 561 GLU GLU C . n 
C 1 562 ALA 562 562 562 ALA ALA C . n 
C 1 563 ARG 563 563 563 ARG ARG C . n 
C 1 564 SER 564 564 ?   ?   ?   C . n 
C 1 565 PRO 565 565 ?   ?   ?   C . n 
C 1 566 LYS 566 566 ?   ?   ?   C . n 
C 1 567 ALA 567 567 ?   ?   ?   C . n 
C 1 568 PRO 568 568 ?   ?   ?   C . n 
C 1 569 GLU 569 569 ?   ?   ?   C . n 
C 1 570 ASP 570 570 ?   ?   ?   C . n 
C 1 571 ASN 571 571 ?   ?   ?   C . n 
C 1 572 ASN 572 572 ?   ?   ?   C . n 
C 1 573 SER 573 573 ?   ?   ?   C . n 
C 1 574 THR 574 574 ?   ?   ?   C . n 
C 1 575 VAL 575 575 ?   ?   ?   C . n 
C 1 576 THR 576 576 ?   ?   ?   C . n 
C 1 577 GLU 577 577 ?   ?   ?   C . n 
C 1 578 GLN 578 578 ?   ?   ?   C . n 
C 1 579 PRO 579 579 ?   ?   ?   C . n 
C 1 580 THR 580 580 ?   ?   ?   C . n 
C 1 581 VAL 581 581 ?   ?   ?   C . n 
C 1 582 GLY 582 582 ?   ?   ?   C . n 
C 1 583 GLN 583 583 ?   ?   ?   C . n 
C 1 584 GLU 584 584 ?   ?   ?   C . n 
C 1 585 GLU 585 585 ?   ?   ?   C . n 
C 1 586 GLU 586 586 ?   ?   ?   C . n 
C 1 587 PRO 587 587 ?   ?   ?   C . n 
C 1 588 ALA 588 588 ?   ?   ?   C . n 
C 1 589 PRO 589 589 589 PRO PRO C . n 
C 1 590 TYR 590 590 590 TYR TYR C . n 
C 1 591 ARG 591 591 591 ARG ARG C . n 
C 1 592 SER 592 592 592 SER SER C . n 
C 1 593 ILE 593 593 593 ILE ILE C . n 
C 1 594 LEU 594 594 594 LEU LEU C . n 
C 1 595 ASP 595 595 595 ASP ASP C . n 
C 1 596 ALA 596 596 596 ALA ALA C . n 
C 1 597 SER 597 597 597 SER SER C . n 
C 1 598 LEU 598 598 598 LEU LEU C . n 
C 1 599 GLU 599 599 599 GLU GLU C . n 
C 1 600 LEU 600 600 600 LEU LEU C . n 
C 1 601 PHE 601 601 601 PHE PHE C . n 
C 1 602 LYS 602 602 602 LYS LYS C . n 
C 1 603 PHE 603 603 603 PHE PHE C . n 
C 1 604 THR 604 604 604 THR THR C . n 
C 1 605 ILE 605 605 605 ILE ILE C . n 
C 1 606 GLY 606 606 606 GLY GLY C . n 
C 1 607 MET 607 607 607 MET MET C . n 
C 1 608 GLY 608 608 608 GLY GLY C . n 
C 1 609 GLU 609 609 609 GLU GLU C . n 
C 1 610 LEU 610 610 610 LEU LEU C . n 
C 1 611 ALA 611 611 611 ALA ALA C . n 
C 1 612 PHE 612 612 612 PHE PHE C . n 
C 1 613 GLN 613 613 613 GLN GLN C . n 
C 1 614 GLU 614 614 614 GLU GLU C . n 
C 1 615 GLN 615 615 615 GLN GLN C . n 
C 1 616 LEU 616 616 616 LEU LEU C . n 
C 1 617 ARG 617 617 617 ARG ARG C . n 
C 1 618 PHE 618 618 618 PHE PHE C . n 
C 1 619 ARG 619 619 619 ARG ARG C . n 
C 1 620 GLY 620 620 620 GLY GLY C . n 
C 1 621 VAL 621 621 621 VAL VAL C . n 
C 1 622 VAL 622 622 622 VAL VAL C . n 
C 1 623 LEU 623 623 623 LEU LEU C . n 
C 1 624 LEU 624 624 624 LEU LEU C . n 
C 1 625 LEU 625 625 625 LEU LEU C . n 
C 1 626 LEU 626 626 626 LEU LEU C . n 
C 1 627 LEU 627 627 627 LEU LEU C . n 
C 1 628 ALA 628 628 628 ALA ALA C . n 
C 1 629 TYR 629 629 629 TYR TYR C . n 
C 1 630 VAL 630 630 630 VAL VAL C . n 
C 1 631 LEU 631 631 631 LEU LEU C . n 
C 1 632 LEU 632 632 632 LEU LEU C . n 
C 1 633 THR 633 633 633 THR THR C . n 
C 1 634 TYR 634 634 634 TYR TYR C . n 
C 1 635 VAL 635 635 635 VAL VAL C . n 
C 1 636 LEU 636 636 636 LEU LEU C . n 
C 1 637 LEU 637 637 637 LEU LEU C . n 
C 1 638 LEU 638 638 638 LEU LEU C . n 
C 1 639 ASN 639 639 639 ASN ASN C . n 
C 1 640 MET 640 640 640 MET MET C . n 
C 1 641 LEU 641 641 641 LEU LEU C . n 
C 1 642 ILE 642 642 642 ILE ILE C . n 
C 1 643 ALA 643 643 643 ALA ALA C . n 
C 1 644 LEU 644 644 644 LEU LEU C . n 
C 1 645 MET 645 645 645 MET MET C . n 
C 1 646 SER 646 646 646 SER SER C . n 
C 1 647 GLU 647 647 647 GLU GLU C . n 
C 1 648 THR 648 648 648 THR THR C . n 
C 1 649 VAL 649 649 649 VAL VAL C . n 
C 1 650 ASN 650 650 650 ASN ASN C . n 
C 1 651 HIS 651 651 651 HIS HIS C . n 
C 1 652 VAL 652 652 652 VAL VAL C . n 
C 1 653 ALA 653 653 653 ALA ALA C . n 
C 1 654 ASP 654 654 654 ASP ASP C . n 
C 1 655 ASN 655 655 655 ASN ASN C . n 
C 1 656 SER 656 656 656 SER SER C . n 
C 1 657 TRP 657 657 657 TRP TRP C . n 
C 1 658 SER 658 658 658 SER SER C . n 
C 1 659 ILE 659 659 659 ILE ILE C . n 
C 1 660 TRP 660 660 660 TRP TRP C . n 
C 1 661 LYS 661 661 661 LYS LYS C . n 
C 1 662 LEU 662 662 662 LEU LEU C . n 
C 1 663 GLN 663 663 663 GLN GLN C . n 
C 1 664 LYS 664 664 664 LYS LYS C . n 
C 1 665 ALA 665 665 665 ALA ALA C . n 
C 1 666 ILE 666 666 666 ILE ILE C . n 
C 1 667 SER 667 667 667 SER SER C . n 
C 1 668 VAL 668 668 668 VAL VAL C . n 
C 1 669 LEU 669 669 669 LEU LEU C . n 
C 1 670 GLU 670 670 670 GLU GLU C . n 
C 1 671 MET 671 671 671 MET MET C . n 
C 1 672 GLU 672 672 672 GLU GLU C . n 
C 1 673 ASN 673 673 673 ASN ASN C . n 
C 1 674 GLY 674 674 674 GLY GLY C . n 
C 1 675 TYR 675 675 675 TYR TYR C . n 
C 1 676 TRP 676 676 676 TRP TRP C . n 
C 1 677 TRP 677 677 677 TRP TRP C . n 
C 1 678 CYS 678 678 678 CYS CYS C . n 
C 1 679 ARG 679 679 679 ARG ARG C . n 
C 1 680 ARG 680 680 680 ARG ARG C . n 
C 1 681 LYS 681 681 681 LYS LYS C . n 
C 1 682 LYS 682 682 682 LYS LYS C . n 
C 1 683 HIS 683 683 683 HIS HIS C . n 
C 1 684 ARG 684 684 684 ARG ARG C . n 
C 1 685 GLU 685 685 685 GLU GLU C . n 
C 1 686 GLY 686 686 686 GLY GLY C . n 
C 1 687 ARG 687 687 687 ARG ARG C . n 
C 1 688 LEU 688 688 688 LEU LEU C . n 
C 1 689 LEU 689 689 689 LEU LEU C . n 
C 1 690 LYS 690 690 690 LYS LYS C . n 
C 1 691 VAL 691 691 691 VAL VAL C . n 
C 1 692 GLY 692 692 692 GLY GLY C . n 
C 1 693 THR 693 693 693 THR THR C . n 
C 1 694 ARG 694 694 694 ARG ARG C . n 
C 1 695 GLY 695 695 ?   ?   ?   C . n 
C 1 696 ASP 696 696 ?   ?   ?   C . n 
C 1 697 GLY 697 697 ?   ?   ?   C . n 
C 1 698 THR 698 698 ?   ?   ?   C . n 
C 1 699 PRO 699 699 699 PRO PRO C . n 
C 1 700 ASP 700 700 700 ASP ASP C . n 
C 1 701 GLU 701 701 701 GLU GLU C . n 
C 1 702 ARG 702 702 702 ARG ARG C . n 
C 1 703 TRP 703 703 703 TRP TRP C . n 
C 1 704 CYS 704 704 704 CYS CYS C . n 
C 1 705 PHE 705 705 705 PHE PHE C . n 
C 1 706 ARG 706 706 706 ARG ARG C . n 
C 1 707 VAL 707 707 707 VAL VAL C . n 
C 1 708 GLU 708 708 708 GLU GLU C . n 
C 1 709 GLU 709 709 709 GLU GLU C . n 
C 1 710 VAL 710 710 710 VAL VAL C . n 
C 1 711 ASN 711 711 711 ASN ASN C . n 
C 1 712 TRP 712 712 712 TRP TRP C . n 
C 1 713 ALA 713 713 713 ALA ALA C . n 
C 1 714 ALA 714 714 714 ALA ALA C . n 
C 1 715 TRP 715 715 715 TRP TRP C . n 
C 1 716 GLU 716 716 716 GLU GLU C . n 
C 1 717 LYS 717 717 717 LYS LYS C . n 
C 1 718 THR 718 718 718 THR THR C . n 
C 1 719 LEU 719 719 719 LEU LEU C . n 
C 1 720 PRO 720 720 ?   ?   ?   C . n 
C 1 721 THR 721 721 ?   ?   ?   C . n 
C 1 722 LEU 722 722 ?   ?   ?   C . n 
C 1 723 SER 723 723 ?   ?   ?   C . n 
C 1 724 ALA 724 724 ?   ?   ?   C . n 
C 1 725 ALA 725 725 ?   ?   ?   C . n 
C 1 726 PRO 726 726 ?   ?   ?   C . n 
C 1 727 SER 727 727 ?   ?   ?   C . n 
C 1 728 GLY 728 728 ?   ?   ?   C . n 
C 1 729 PRO 729 729 ?   ?   ?   C . n 
C 1 730 GLY 730 730 ?   ?   ?   C . n 
C 1 731 ILE 731 731 ?   ?   ?   C . n 
C 1 732 THR 732 732 ?   ?   ?   C . n 
C 1 733 GLY 733 733 ?   ?   ?   C . n 
C 1 734 ASN 734 734 ?   ?   ?   C . n 
C 1 735 LYS 735 735 ?   ?   ?   C . n 
C 1 736 LYS 736 736 ?   ?   ?   C . n 
C 1 737 ASN 737 737 ?   ?   ?   C . n 
C 1 738 PRO 738 738 ?   ?   ?   C . n 
C 1 739 THR 739 739 ?   ?   ?   C . n 
C 1 740 SER 740 740 ?   ?   ?   C . n 
C 1 741 LYS 741 741 ?   ?   ?   C . n 
C 1 742 PRO 742 742 ?   ?   ?   C . n 
C 1 743 GLY 743 743 ?   ?   ?   C . n 
C 1 744 LYS 744 744 ?   ?   ?   C . n 
C 1 745 ASN 745 745 ?   ?   ?   C . n 
C 1 746 SER 746 746 ?   ?   ?   C . n 
C 1 747 ALA 747 747 ?   ?   ?   C . n 
C 1 748 SER 748 748 ?   ?   ?   C . n 
C 1 749 GLU 749 749 ?   ?   ?   C . n 
C 1 750 GLU 750 750 ?   ?   ?   C . n 
C 1 751 ASP 751 751 ?   ?   ?   C . n 
C 1 752 HIS 752 752 ?   ?   ?   C . n 
C 1 753 LEU 753 753 ?   ?   ?   C . n 
C 1 754 PRO 754 754 ?   ?   ?   C . n 
C 1 755 LEU 755 755 ?   ?   ?   C . n 
C 1 756 GLN 756 756 ?   ?   ?   C . n 
C 1 757 VAL 757 757 ?   ?   ?   C . n 
C 1 758 LEU 758 758 ?   ?   ?   C . n 
C 1 759 GLN 759 759 ?   ?   ?   C . n 
C 1 760 SER 760 760 ?   ?   ?   C . n 
C 1 761 PRO 761 761 ?   ?   ?   C . n 
D 1 1   MET 1   1   ?   ?   ?   D . n 
D 1 2   THR 2   2   ?   ?   ?   D . n 
D 1 3   SER 3   3   ?   ?   ?   D . n 
D 1 4   ALA 4   4   ?   ?   ?   D . n 
D 1 5   SER 5   5   ?   ?   ?   D . n 
D 1 6   SER 6   6   ?   ?   ?   D . n 
D 1 7   PRO 7   7   ?   ?   ?   D . n 
D 1 8   PRO 8   8   ?   ?   ?   D . n 
D 1 9   ALA 9   9   ?   ?   ?   D . n 
D 1 10  PHE 10  10  ?   ?   ?   D . n 
D 1 11  ARG 11  11  ?   ?   ?   D . n 
D 1 12  LEU 12  12  ?   ?   ?   D . n 
D 1 13  GLU 13  13  ?   ?   ?   D . n 
D 1 14  THR 14  14  ?   ?   ?   D . n 
D 1 15  SER 15  15  ?   ?   ?   D . n 
D 1 16  ASP 16  16  ?   ?   ?   D . n 
D 1 17  GLY 17  17  ?   ?   ?   D . n 
D 1 18  ASP 18  18  ?   ?   ?   D . n 
D 1 19  GLU 19  19  ?   ?   ?   D . n 
D 1 20  GLU 20  20  ?   ?   ?   D . n 
D 1 21  GLY 21  21  ?   ?   ?   D . n 
D 1 22  ASN 22  22  ?   ?   ?   D . n 
D 1 23  ALA 23  23  ?   ?   ?   D . n 
D 1 24  GLU 24  24  ?   ?   ?   D . n 
D 1 25  VAL 25  25  ?   ?   ?   D . n 
D 1 26  ASN 26  26  ?   ?   ?   D . n 
D 1 27  LYS 27  27  ?   ?   ?   D . n 
D 1 28  GLY 28  28  ?   ?   ?   D . n 
D 1 29  LYS 29  29  ?   ?   ?   D . n 
D 1 30  GLN 30  30  ?   ?   ?   D . n 
D 1 31  GLU 31  31  ?   ?   ?   D . n 
D 1 32  PRO 32  32  ?   ?   ?   D . n 
D 1 33  PRO 33  33  ?   ?   ?   D . n 
D 1 34  PRO 34  34  ?   ?   ?   D . n 
D 1 35  MET 35  35  ?   ?   ?   D . n 
D 1 36  GLU 36  36  ?   ?   ?   D . n 
D 1 37  SER 37  37  ?   ?   ?   D . n 
D 1 38  PRO 38  38  ?   ?   ?   D . n 
D 1 39  PHE 39  39  ?   ?   ?   D . n 
D 1 40  GLN 40  40  ?   ?   ?   D . n 
D 1 41  ARG 41  41  ?   ?   ?   D . n 
D 1 42  GLU 42  42  ?   ?   ?   D . n 
D 1 43  ASP 43  43  ?   ?   ?   D . n 
D 1 44  ARG 44  44  ?   ?   ?   D . n 
D 1 45  ASN 45  45  ?   ?   ?   D . n 
D 1 46  SER 46  46  ?   ?   ?   D . n 
D 1 47  SER 47  47  ?   ?   ?   D . n 
D 1 48  PRO 48  48  ?   ?   ?   D . n 
D 1 49  GLN 49  49  ?   ?   ?   D . n 
D 1 50  ILE 50  50  ?   ?   ?   D . n 
D 1 51  LYS 51  51  ?   ?   ?   D . n 
D 1 52  VAL 52  52  ?   ?   ?   D . n 
D 1 53  ASN 53  53  ?   ?   ?   D . n 
D 1 54  LEU 54  54  ?   ?   ?   D . n 
D 1 55  ASN 55  55  ?   ?   ?   D . n 
D 1 56  PHE 56  56  ?   ?   ?   D . n 
D 1 57  ILE 57  57  ?   ?   ?   D . n 
D 1 58  LYS 58  58  ?   ?   ?   D . n 
D 1 59  ARG 59  59  ?   ?   ?   D . n 
D 1 60  PRO 60  60  ?   ?   ?   D . n 
D 1 61  PRO 61  61  ?   ?   ?   D . n 
D 1 62  LYS 62  62  ?   ?   ?   D . n 
D 1 63  ASN 63  63  ?   ?   ?   D . n 
D 1 64  THR 64  64  ?   ?   ?   D . n 
D 1 65  SER 65  65  ?   ?   ?   D . n 
D 1 66  ALA 66  66  ?   ?   ?   D . n 
D 1 67  PRO 67  67  ?   ?   ?   D . n 
D 1 68  SER 68  68  ?   ?   ?   D . n 
D 1 69  GLN 69  69  ?   ?   ?   D . n 
D 1 70  GLN 70  70  ?   ?   ?   D . n 
D 1 71  GLU 71  71  ?   ?   ?   D . n 
D 1 72  PRO 72  72  ?   ?   ?   D . n 
D 1 73  ASP 73  73  ?   ?   ?   D . n 
D 1 74  ARG 74  74  74  ARG ARG D . n 
D 1 75  PHE 75  75  75  PHE PHE D . n 
D 1 76  ASP 76  76  76  ASP ASP D . n 
D 1 77  ARG 77  77  77  ARG ARG D . n 
D 1 78  ASP 78  78  78  ASP ASP D . n 
D 1 79  ARG 79  79  79  ARG ARG D . n 
D 1 80  LEU 80  80  80  LEU LEU D . n 
D 1 81  PHE 81  81  81  PHE PHE D . n 
D 1 82  SER 82  82  82  SER SER D . n 
D 1 83  VAL 83  83  83  VAL VAL D . n 
D 1 84  VAL 84  84  84  VAL VAL D . n 
D 1 85  SER 85  85  85  SER SER D . n 
D 1 86  ARG 86  86  86  ARG ARG D . n 
D 1 87  GLY 87  87  87  GLY GLY D . n 
D 1 88  VAL 88  88  88  VAL VAL D . n 
D 1 89  PRO 89  89  89  PRO PRO D . n 
D 1 90  GLU 90  90  90  GLU GLU D . n 
D 1 91  GLU 91  91  91  GLU GLU D . n 
D 1 92  LEU 92  92  92  LEU LEU D . n 
D 1 93  THR 93  93  93  THR THR D . n 
D 1 94  GLY 94  94  94  GLY GLY D . n 
D 1 95  LEU 95  95  95  LEU LEU D . n 
D 1 96  LEU 96  96  96  LEU LEU D . n 
D 1 97  GLU 97  97  97  GLU GLU D . n 
D 1 98  TYR 98  98  98  TYR TYR D . n 
D 1 99  LEU 99  99  99  LEU LEU D . n 
D 1 100 ARG 100 100 100 ARG ARG D . n 
D 1 101 TRP 101 101 101 TRP TRP D . n 
D 1 102 ASN 102 102 102 ASN ASN D . n 
D 1 103 SER 103 103 103 SER SER D . n 
D 1 104 LYS 104 104 104 LYS LYS D . n 
D 1 105 TYR 105 105 105 TYR TYR D . n 
D 1 106 LEU 106 106 106 LEU LEU D . n 
D 1 107 THR 107 107 107 THR THR D . n 
D 1 108 ASP 108 108 108 ASP ASP D . n 
D 1 109 SER 109 109 109 SER SER D . n 
D 1 110 ALA 110 110 110 ALA ALA D . n 
D 1 111 TYR 111 111 111 TYR TYR D . n 
D 1 112 THR 112 112 112 THR THR D . n 
D 1 113 GLU 113 113 113 GLU GLU D . n 
D 1 114 GLY 114 114 114 GLY GLY D . n 
D 1 115 SER 115 115 115 SER SER D . n 
D 1 116 THR 116 116 116 THR THR D . n 
D 1 117 GLY 117 117 117 GLY GLY D . n 
D 1 118 LYS 118 118 118 LYS LYS D . n 
D 1 119 THR 119 119 119 THR THR D . n 
D 1 120 CYS 120 120 120 CYS CYS D . n 
D 1 121 LEU 121 121 121 LEU LEU D . n 
D 1 122 MET 122 122 122 MET MET D . n 
D 1 123 LYS 123 123 123 LYS LYS D . n 
D 1 124 ALA 124 124 124 ALA ALA D . n 
D 1 125 VAL 125 125 125 VAL VAL D . n 
D 1 126 LEU 126 126 126 LEU LEU D . n 
D 1 127 ASN 127 127 127 ASN ASN D . n 
D 1 128 LEU 128 128 128 LEU LEU D . n 
D 1 129 GLN 129 129 129 GLN GLN D . n 
D 1 130 ASP 130 130 130 ASP ASP D . n 
D 1 131 GLY 131 131 131 GLY GLY D . n 
D 1 132 VAL 132 132 132 VAL VAL D . n 
D 1 133 ASN 133 133 133 ASN ASN D . n 
D 1 134 ALA 134 134 134 ALA ALA D . n 
D 1 135 CYS 135 135 135 CYS CYS D . n 
D 1 136 ILE 136 136 136 ILE ILE D . n 
D 1 137 MET 137 137 137 MET MET D . n 
D 1 138 PRO 138 138 138 PRO PRO D . n 
D 1 139 LEU 139 139 139 LEU LEU D . n 
D 1 140 LEU 140 140 140 LEU LEU D . n 
D 1 141 GLN 141 141 141 GLN GLN D . n 
D 1 142 ILE 142 142 142 ILE ILE D . n 
D 1 143 ASP 143 143 143 ASP ASP D . n 
D 1 144 LYS 144 144 144 LYS LYS D . n 
D 1 145 ASP 145 145 145 ASP ASP D . n 
D 1 146 SER 146 146 146 SER SER D . n 
D 1 147 GLY 147 147 147 GLY GLY D . n 
D 1 148 ASN 148 148 148 ASN ASN D . n 
D 1 149 PRO 149 149 149 PRO PRO D . n 
D 1 150 LYS 150 150 150 LYS LYS D . n 
D 1 151 LEU 151 151 151 LEU LEU D . n 
D 1 152 LEU 152 152 152 LEU LEU D . n 
D 1 153 VAL 153 153 153 VAL VAL D . n 
D 1 154 ASN 154 154 154 ASN ASN D . n 
D 1 155 ALA 155 155 155 ALA ALA D . n 
D 1 156 GLN 156 156 156 GLN GLN D . n 
D 1 157 CYS 157 157 157 CYS CYS D . n 
D 1 158 THR 158 158 158 THR THR D . n 
D 1 159 ASP 159 159 159 ASP ASP D . n 
D 1 160 GLU 160 160 160 GLU GLU D . n 
D 1 161 PHE 161 161 161 PHE PHE D . n 
D 1 162 TYR 162 162 162 TYR TYR D . n 
D 1 163 GLN 163 163 163 GLN GLN D . n 
D 1 164 GLY 164 164 164 GLY GLY D . n 
D 1 165 HIS 165 165 165 HIS HIS D . n 
D 1 166 SER 166 166 166 SER SER D . n 
D 1 167 ALA 167 167 167 ALA ALA D . n 
D 1 168 LEU 168 168 168 LEU LEU D . n 
D 1 169 HIS 169 169 169 HIS HIS D . n 
D 1 170 ILE 170 170 170 ILE ILE D . n 
D 1 171 ALA 171 171 171 ALA ALA D . n 
D 1 172 ILE 172 172 172 ILE ILE D . n 
D 1 173 GLU 173 173 173 GLU GLU D . n 
D 1 174 LYS 174 174 174 LYS LYS D . n 
D 1 175 ARG 175 175 175 ARG ARG D . n 
D 1 176 SER 176 176 176 SER SER D . n 
D 1 177 LEU 177 177 177 LEU LEU D . n 
D 1 178 GLN 178 178 178 GLN GLN D . n 
D 1 179 CYS 179 179 179 CYS CYS D . n 
D 1 180 VAL 180 180 180 VAL VAL D . n 
D 1 181 LYS 181 181 181 LYS LYS D . n 
D 1 182 LEU 182 182 182 LEU LEU D . n 
D 1 183 LEU 183 183 183 LEU LEU D . n 
D 1 184 VAL 184 184 184 VAL VAL D . n 
D 1 185 GLU 185 185 185 GLU GLU D . n 
D 1 186 ASN 186 186 186 ASN ASN D . n 
D 1 187 GLY 187 187 187 GLY GLY D . n 
D 1 188 ALA 188 188 188 ALA ALA D . n 
D 1 189 ASP 189 189 189 ASP ASP D . n 
D 1 190 VAL 190 190 190 VAL VAL D . n 
D 1 191 HIS 191 191 191 HIS HIS D . n 
D 1 192 LEU 192 192 192 LEU LEU D . n 
D 1 193 ARG 193 193 193 ARG ARG D . n 
D 1 194 ALA 194 194 194 ALA ALA D . n 
D 1 195 CYS 195 195 195 CYS CYS D . n 
D 1 196 GLY 196 196 196 GLY GLY D . n 
D 1 197 ARG 197 197 197 ARG ARG D . n 
D 1 198 PHE 198 198 198 PHE PHE D . n 
D 1 199 PHE 199 199 199 PHE PHE D . n 
D 1 200 GLN 200 200 200 GLN GLN D . n 
D 1 201 LYS 201 201 201 LYS LYS D . n 
D 1 202 HIS 202 202 202 HIS HIS D . n 
D 1 203 GLN 203 203 203 GLN GLN D . n 
D 1 204 GLY 204 204 204 GLY GLY D . n 
D 1 205 THR 205 205 205 THR THR D . n 
D 1 206 CYS 206 206 206 CYS CYS D . n 
D 1 207 PHE 207 207 207 PHE PHE D . n 
D 1 208 TYR 208 208 208 TYR TYR D . n 
D 1 209 PHE 209 209 209 PHE PHE D . n 
D 1 210 GLY 210 210 210 GLY GLY D . n 
D 1 211 GLU 211 211 211 GLU GLU D . n 
D 1 212 LEU 212 212 212 LEU LEU D . n 
D 1 213 PRO 213 213 213 PRO PRO D . n 
D 1 214 LEU 214 214 214 LEU LEU D . n 
D 1 215 SER 215 215 215 SER SER D . n 
D 1 216 LEU 216 216 216 LEU LEU D . n 
D 1 217 ALA 217 217 217 ALA ALA D . n 
D 1 218 ALA 218 218 218 ALA ALA D . n 
D 1 219 CYS 219 219 219 CYS CYS D . n 
D 1 220 THR 220 220 220 THR THR D . n 
D 1 221 LYS 221 221 221 LYS LYS D . n 
D 1 222 GLN 222 222 222 GLN GLN D . n 
D 1 223 TRP 223 223 223 TRP TRP D . n 
D 1 224 ASP 224 224 224 ASP ASP D . n 
D 1 225 VAL 225 225 225 VAL VAL D . n 
D 1 226 VAL 226 226 226 VAL VAL D . n 
D 1 227 THR 227 227 227 THR THR D . n 
D 1 228 TYR 228 228 228 TYR TYR D . n 
D 1 229 LEU 229 229 229 LEU LEU D . n 
D 1 230 LEU 230 230 230 LEU LEU D . n 
D 1 231 GLU 231 231 231 GLU GLU D . n 
D 1 232 ASN 232 232 232 ASN ASN D . n 
D 1 233 PRO 233 233 233 PRO PRO D . n 
D 1 234 HIS 234 234 234 HIS HIS D . n 
D 1 235 GLN 235 235 235 GLN GLN D . n 
D 1 236 PRO 236 236 236 PRO PRO D . n 
D 1 237 ALA 237 237 237 ALA ALA D . n 
D 1 238 SER 238 238 238 SER SER D . n 
D 1 239 LEU 239 239 239 LEU LEU D . n 
D 1 240 GLU 240 240 240 GLU GLU D . n 
D 1 241 ALA 241 241 241 ALA ALA D . n 
D 1 242 THR 242 242 242 THR THR D . n 
D 1 243 ASP 243 243 243 ASP ASP D . n 
D 1 244 SER 244 244 244 SER SER D . n 
D 1 245 LEU 245 245 245 LEU LEU D . n 
D 1 246 GLY 246 246 246 GLY GLY D . n 
D 1 247 ASN 247 247 247 ASN ASN D . n 
D 1 248 THR 248 248 248 THR THR D . n 
D 1 249 VAL 249 249 249 VAL VAL D . n 
D 1 250 LEU 250 250 250 LEU LEU D . n 
D 1 251 HIS 251 251 251 HIS HIS D . n 
D 1 252 ALA 252 252 252 ALA ALA D . n 
D 1 253 LEU 253 253 253 LEU LEU D . n 
D 1 254 VAL 254 254 254 VAL VAL D . n 
D 1 255 MET 255 255 255 MET MET D . n 
D 1 256 ILE 256 256 256 ILE ILE D . n 
D 1 257 ALA 257 257 257 ALA ALA D . n 
D 1 258 ASP 258 258 258 ASP ASP D . n 
D 1 259 ASN 259 259 259 ASN ASN D . n 
D 1 260 SER 260 260 260 SER SER D . n 
D 1 261 PRO 261 261 261 PRO PRO D . n 
D 1 262 GLU 262 262 262 GLU GLU D . n 
D 1 263 ASN 263 263 263 ASN ASN D . n 
D 1 264 SER 264 264 264 SER SER D . n 
D 1 265 ALA 265 265 265 ALA ALA D . n 
D 1 266 LEU 266 266 266 LEU LEU D . n 
D 1 267 VAL 267 267 267 VAL VAL D . n 
D 1 268 ILE 268 268 268 ILE ILE D . n 
D 1 269 HIS 269 269 269 HIS HIS D . n 
D 1 270 MET 270 270 270 MET MET D . n 
D 1 271 TYR 271 271 271 TYR TYR D . n 
D 1 272 ASP 272 272 272 ASP ASP D . n 
D 1 273 GLY 273 273 273 GLY GLY D . n 
D 1 274 LEU 274 274 274 LEU LEU D . n 
D 1 275 LEU 275 275 275 LEU LEU D . n 
D 1 276 GLN 276 276 276 GLN GLN D . n 
D 1 277 MET 277 277 277 MET MET D . n 
D 1 278 GLY 278 278 278 GLY GLY D . n 
D 1 279 ALA 279 279 279 ALA ALA D . n 
D 1 280 ARG 280 280 280 ARG ARG D . n 
D 1 281 LEU 281 281 281 LEU LEU D . n 
D 1 282 CYS 282 282 282 CYS CYS D . n 
D 1 283 PRO 283 283 283 PRO PRO D . n 
D 1 284 THR 284 284 284 THR THR D . n 
D 1 285 VAL 285 285 285 VAL VAL D . n 
D 1 286 GLN 286 286 286 GLN GLN D . n 
D 1 287 LEU 287 287 287 LEU LEU D . n 
D 1 288 GLU 288 288 288 GLU GLU D . n 
D 1 289 GLU 289 289 289 GLU GLU D . n 
D 1 290 ILE 290 290 290 ILE ILE D . n 
D 1 291 SER 291 291 291 SER SER D . n 
D 1 292 ASN 292 292 292 ASN ASN D . n 
D 1 293 HIS 293 293 293 HIS HIS D . n 
D 1 294 GLN 294 294 294 GLN GLN D . n 
D 1 295 GLY 295 295 295 GLY GLY D . n 
D 1 296 LEU 296 296 296 LEU LEU D . n 
D 1 297 THR 297 297 297 THR THR D . n 
D 1 298 PRO 298 298 298 PRO PRO D . n 
D 1 299 LEU 299 299 299 LEU LEU D . n 
D 1 300 LYS 300 300 300 LYS LYS D . n 
D 1 301 LEU 301 301 301 LEU LEU D . n 
D 1 302 ALA 302 302 302 ALA ALA D . n 
D 1 303 ALA 303 303 303 ALA ALA D . n 
D 1 304 LYS 304 304 304 LYS LYS D . n 
D 1 305 GLU 305 305 305 GLU GLU D . n 
D 1 306 GLY 306 306 306 GLY GLY D . n 
D 1 307 LYS 307 307 307 LYS LYS D . n 
D 1 308 ILE 308 308 308 ILE ILE D . n 
D 1 309 GLU 309 309 309 GLU GLU D . n 
D 1 310 ILE 310 310 310 ILE ILE D . n 
D 1 311 PHE 311 311 311 PHE PHE D . n 
D 1 312 ARG 312 312 312 ARG ARG D . n 
D 1 313 HIS 313 313 313 HIS HIS D . n 
D 1 314 ILE 314 314 314 ILE ILE D . n 
D 1 315 LEU 315 315 315 LEU LEU D . n 
D 1 316 GLN 316 316 316 GLN GLN D . n 
D 1 317 ARG 317 317 317 ARG ARG D . n 
D 1 318 GLU 318 318 318 GLU GLU D . n 
D 1 319 PHE 319 319 319 PHE PHE D . n 
D 1 320 SER 320 320 320 SER SER D . n 
D 1 321 GLY 321 321 321 GLY GLY D . n 
D 1 322 PRO 322 322 322 PRO PRO D . n 
D 1 323 TYR 323 323 323 TYR TYR D . n 
D 1 324 GLN 324 324 324 GLN GLN D . n 
D 1 325 PRO 325 325 325 PRO PRO D . n 
D 1 326 LEU 326 326 326 LEU LEU D . n 
D 1 327 SER 327 327 327 SER SER D . n 
D 1 328 ARG 328 328 328 ARG ARG D . n 
D 1 329 LYS 329 329 329 LYS LYS D . n 
D 1 330 PHE 330 330 330 PHE PHE D . n 
D 1 331 THR 331 331 331 THR THR D . n 
D 1 332 GLU 332 332 332 GLU GLU D . n 
D 1 333 TRP 333 333 333 TRP TRP D . n 
D 1 334 CYS 334 334 334 CYS CYS D . n 
D 1 335 TYR 335 335 335 TYR TYR D . n 
D 1 336 GLY 336 336 336 GLY GLY D . n 
D 1 337 PRO 337 337 337 PRO PRO D . n 
D 1 338 VAL 338 338 338 VAL VAL D . n 
D 1 339 ARG 339 339 339 ARG ARG D . n 
D 1 340 VAL 340 340 340 VAL VAL D . n 
D 1 341 SER 341 341 341 SER SER D . n 
D 1 342 LEU 342 342 342 LEU LEU D . n 
D 1 343 TYR 343 343 343 TYR TYR D . n 
D 1 344 ASP 344 344 344 ASP ASP D . n 
D 1 345 LEU 345 345 345 LEU LEU D . n 
D 1 346 SER 346 346 346 SER SER D . n 
D 1 347 SER 347 347 347 SER SER D . n 
D 1 348 VAL 348 348 348 VAL VAL D . n 
D 1 349 ASP 349 349 349 ASP ASP D . n 
D 1 350 SER 350 350 350 SER SER D . n 
D 1 351 TRP 351 351 351 TRP TRP D . n 
D 1 352 GLU 352 352 352 GLU GLU D . n 
D 1 353 LYS 353 353 353 LYS LYS D . n 
D 1 354 ASN 354 354 354 ASN ASN D . n 
D 1 355 SER 355 355 355 SER SER D . n 
D 1 356 VAL 356 356 356 VAL VAL D . n 
D 1 357 LEU 357 357 357 LEU LEU D . n 
D 1 358 GLU 358 358 358 GLU GLU D . n 
D 1 359 ILE 359 359 359 ILE ILE D . n 
D 1 360 ILE 360 360 360 ILE ILE D . n 
D 1 361 ALA 361 361 361 ALA ALA D . n 
D 1 362 PHE 362 362 362 PHE PHE D . n 
D 1 363 HIS 363 363 363 HIS HIS D . n 
D 1 364 CYS 364 364 364 CYS CYS D . n 
D 1 365 LYS 365 365 365 LYS LYS D . n 
D 1 366 SER 366 366 366 SER SER D . n 
D 1 367 PRO 367 367 367 PRO PRO D . n 
D 1 368 ASN 368 368 368 ASN ASN D . n 
D 1 369 ARG 369 369 369 ARG ARG D . n 
D 1 370 HIS 370 370 370 HIS HIS D . n 
D 1 371 ARG 371 371 371 ARG ARG D . n 
D 1 372 MET 372 372 372 MET MET D . n 
D 1 373 VAL 373 373 373 VAL VAL D . n 
D 1 374 VAL 374 374 374 VAL VAL D . n 
D 1 375 LEU 375 375 375 LEU LEU D . n 
D 1 376 GLU 376 376 376 GLU GLU D . n 
D 1 377 PRO 377 377 377 PRO PRO D . n 
D 1 378 LEU 378 378 378 LEU LEU D . n 
D 1 379 ASN 379 379 379 ASN ASN D . n 
D 1 380 LYS 380 380 380 LYS LYS D . n 
D 1 381 LEU 381 381 381 LEU LEU D . n 
D 1 382 LEU 382 382 382 LEU LEU D . n 
D 1 383 GLN 383 383 383 GLN GLN D . n 
D 1 384 GLU 384 384 384 GLU GLU D . n 
D 1 385 LYS 385 385 385 LYS LYS D . n 
D 1 386 TRP 386 386 386 TRP TRP D . n 
D 1 387 ASP 387 387 387 ASP ASP D . n 
D 1 388 ARG 388 388 388 ARG ARG D . n 
D 1 389 LEU 389 389 389 LEU LEU D . n 
D 1 390 VAL 390 390 390 VAL VAL D . n 
D 1 391 SER 391 391 391 SER SER D . n 
D 1 392 ARG 392 392 392 ARG ARG D . n 
D 1 393 PHE 393 393 393 PHE PHE D . n 
D 1 394 PHE 394 394 394 PHE PHE D . n 
D 1 395 PHE 395 395 395 PHE PHE D . n 
D 1 396 ASN 396 396 396 ASN ASN D . n 
D 1 397 PHE 397 397 397 PHE PHE D . n 
D 1 398 ALA 398 398 398 ALA ALA D . n 
D 1 399 CYS 399 399 399 CYS CYS D . n 
D 1 400 TYR 400 400 400 TYR TYR D . n 
D 1 401 LEU 401 401 401 LEU LEU D . n 
D 1 402 VAL 402 402 402 VAL VAL D . n 
D 1 403 TYR 403 403 403 TYR TYR D . n 
D 1 404 MET 404 404 404 MET MET D . n 
D 1 405 PHE 405 405 405 PHE PHE D . n 
D 1 406 ILE 406 406 406 ILE ILE D . n 
D 1 407 PHE 407 407 407 PHE PHE D . n 
D 1 408 THR 408 408 408 THR THR D . n 
D 1 409 VAL 409 409 409 VAL VAL D . n 
D 1 410 VAL 410 410 410 VAL VAL D . n 
D 1 411 ALA 411 411 411 ALA ALA D . n 
D 1 412 TYR 412 412 412 TYR TYR D . n 
D 1 413 HIS 413 413 413 HIS HIS D . n 
D 1 414 GLN 414 414 414 GLN GLN D . n 
D 1 415 PRO 415 415 415 PRO PRO D . n 
D 1 416 SER 416 416 416 SER SER D . n 
D 1 417 LEU 417 417 417 LEU LEU D . n 
D 1 418 ASP 418 418 ?   ?   ?   D . n 
D 1 419 GLN 419 419 ?   ?   ?   D . n 
D 1 420 PRO 420 420 ?   ?   ?   D . n 
D 1 421 ALA 421 421 ?   ?   ?   D . n 
D 1 422 ILE 422 422 ?   ?   ?   D . n 
D 1 423 PRO 423 423 ?   ?   ?   D . n 
D 1 424 SER 424 424 ?   ?   ?   D . n 
D 1 425 SER 425 425 ?   ?   ?   D . n 
D 1 426 LYS 426 426 ?   ?   ?   D . n 
D 1 427 ALA 427 427 ?   ?   ?   D . n 
D 1 428 THR 428 428 ?   ?   ?   D . n 
D 1 429 PHE 429 429 429 PHE PHE D . n 
D 1 430 GLY 430 430 430 GLY GLY D . n 
D 1 431 GLU 431 431 431 GLU GLU D . n 
D 1 432 SER 432 432 432 SER SER D . n 
D 1 433 MET 433 433 433 MET MET D . n 
D 1 434 LEU 434 434 434 LEU LEU D . n 
D 1 435 LEU 435 435 435 LEU LEU D . n 
D 1 436 LEU 436 436 436 LEU LEU D . n 
D 1 437 GLY 437 437 437 GLY GLY D . n 
D 1 438 HIS 438 438 438 HIS HIS D . n 
D 1 439 ILE 439 439 439 ILE ILE D . n 
D 1 440 LEU 440 440 440 LEU LEU D . n 
D 1 441 ILE 441 441 441 ILE ILE D . n 
D 1 442 LEU 442 442 442 LEU LEU D . n 
D 1 443 LEU 443 443 443 LEU LEU D . n 
D 1 444 GLY 444 444 444 GLY GLY D . n 
D 1 445 GLY 445 445 445 GLY GLY D . n 
D 1 446 ILE 446 446 446 ILE ILE D . n 
D 1 447 TYR 447 447 447 TYR TYR D . n 
D 1 448 LEU 448 448 448 LEU LEU D . n 
D 1 449 LEU 449 449 449 LEU LEU D . n 
D 1 450 LEU 450 450 450 LEU LEU D . n 
D 1 451 GLY 451 451 451 GLY GLY D . n 
D 1 452 GLN 452 452 452 GLN GLN D . n 
D 1 453 LEU 453 453 453 LEU LEU D . n 
D 1 454 TRP 454 454 454 TRP TRP D . n 
D 1 455 TYR 455 455 455 TYR TYR D . n 
D 1 456 PHE 456 456 456 PHE PHE D . n 
D 1 457 TRP 457 457 457 TRP TRP D . n 
D 1 458 ARG 458 458 458 ARG ARG D . n 
D 1 459 ARG 459 459 459 ARG ARG D . n 
D 1 460 ARG 460 460 460 ARG ARG D . n 
D 1 461 LEU 461 461 461 LEU LEU D . n 
D 1 462 PHE 462 462 462 PHE PHE D . n 
D 1 463 ILE 463 463 463 ILE ILE D . n 
D 1 464 TRP 464 464 464 TRP TRP D . n 
D 1 465 ILE 465 465 465 ILE ILE D . n 
D 1 466 SER 466 466 466 SER SER D . n 
D 1 467 PHE 467 467 467 PHE PHE D . n 
D 1 468 MET 468 468 468 MET MET D . n 
D 1 469 ASP 469 469 469 ASP ASP D . n 
D 1 470 SER 470 470 470 SER SER D . n 
D 1 471 TYR 471 471 471 TYR TYR D . n 
D 1 472 PHE 472 472 472 PHE PHE D . n 
D 1 473 GLU 473 473 473 GLU GLU D . n 
D 1 474 ILE 474 474 474 ILE ILE D . n 
D 1 475 LEU 475 475 475 LEU LEU D . n 
D 1 476 PHE 476 476 476 PHE PHE D . n 
D 1 477 LEU 477 477 477 LEU LEU D . n 
D 1 478 LEU 478 478 478 LEU LEU D . n 
D 1 479 GLN 479 479 479 GLN GLN D . n 
D 1 480 ALA 480 480 480 ALA ALA D . n 
D 1 481 LEU 481 481 481 LEU LEU D . n 
D 1 482 LEU 482 482 482 LEU LEU D . n 
D 1 483 THR 483 483 483 THR THR D . n 
D 1 484 VAL 484 484 484 VAL VAL D . n 
D 1 485 LEU 485 485 485 LEU LEU D . n 
D 1 486 SER 486 486 486 SER SER D . n 
D 1 487 GLN 487 487 487 GLN GLN D . n 
D 1 488 VAL 488 488 488 VAL VAL D . n 
D 1 489 LEU 489 489 489 LEU LEU D . n 
D 1 490 ARG 490 490 490 ARG ARG D . n 
D 1 491 PHE 491 491 491 PHE PHE D . n 
D 1 492 MET 492 492 492 MET MET D . n 
D 1 493 GLU 493 493 493 GLU GLU D . n 
D 1 494 THR 494 494 494 THR THR D . n 
D 1 495 GLU 495 495 495 GLU GLU D . n 
D 1 496 TRP 496 496 496 TRP TRP D . n 
D 1 497 TYR 497 497 497 TYR TYR D . n 
D 1 498 LEU 498 498 498 LEU LEU D . n 
D 1 499 PRO 499 499 499 PRO PRO D . n 
D 1 500 LEU 500 500 500 LEU LEU D . n 
D 1 501 LEU 501 501 501 LEU LEU D . n 
D 1 502 VAL 502 502 502 VAL VAL D . n 
D 1 503 LEU 503 503 503 LEU LEU D . n 
D 1 504 SER 504 504 504 SER SER D . n 
D 1 505 LEU 505 505 505 LEU LEU D . n 
D 1 506 VAL 506 506 506 VAL VAL D . n 
D 1 507 LEU 507 507 507 LEU LEU D . n 
D 1 508 GLY 508 508 508 GLY GLY D . n 
D 1 509 TRP 509 509 509 TRP TRP D . n 
D 1 510 LEU 510 510 510 LEU LEU D . n 
D 1 511 ASN 511 511 511 ASN ASN D . n 
D 1 512 LEU 512 512 512 LEU LEU D . n 
D 1 513 LEU 513 513 513 LEU LEU D . n 
D 1 514 TYR 514 514 514 TYR TYR D . n 
D 1 515 TYR 515 515 515 TYR TYR D . n 
D 1 516 THR 516 516 516 THR THR D . n 
D 1 517 ARG 517 517 517 ARG ARG D . n 
D 1 518 GLY 518 518 518 GLY GLY D . n 
D 1 519 PHE 519 519 519 PHE PHE D . n 
D 1 520 GLN 520 520 520 GLN GLN D . n 
D 1 521 HIS 521 521 521 HIS HIS D . n 
D 1 522 THR 522 522 522 THR THR D . n 
D 1 523 GLY 523 523 523 GLY GLY D . n 
D 1 524 ILE 524 524 524 ILE ILE D . n 
D 1 525 TYR 525 525 525 TYR TYR D . n 
D 1 526 SER 526 526 526 SER SER D . n 
D 1 527 VAL 527 527 527 VAL VAL D . n 
D 1 528 MET 528 528 528 MET MET D . n 
D 1 529 ILE 529 529 529 ILE ILE D . n 
D 1 530 GLN 530 530 530 GLN GLN D . n 
D 1 531 LYS 531 531 531 LYS LYS D . n 
D 1 532 VAL 532 532 532 VAL VAL D . n 
D 1 533 ILE 533 533 533 ILE ILE D . n 
D 1 534 LEU 534 534 534 LEU LEU D . n 
D 1 535 ARG 535 535 535 ARG ARG D . n 
D 1 536 ASP 536 536 536 ASP ASP D . n 
D 1 537 LEU 537 537 537 LEU LEU D . n 
D 1 538 LEU 538 538 538 LEU LEU D . n 
D 1 539 ARG 539 539 539 ARG ARG D . n 
D 1 540 PHE 540 540 540 PHE PHE D . n 
D 1 541 LEU 541 541 541 LEU LEU D . n 
D 1 542 LEU 542 542 542 LEU LEU D . n 
D 1 543 VAL 543 543 543 VAL VAL D . n 
D 1 544 TYR 544 544 544 TYR TYR D . n 
D 1 545 LEU 545 545 545 LEU LEU D . n 
D 1 546 VAL 546 546 546 VAL VAL D . n 
D 1 547 PHE 547 547 547 PHE PHE D . n 
D 1 548 LEU 548 548 548 LEU LEU D . n 
D 1 549 PHE 549 549 549 PHE PHE D . n 
D 1 550 GLY 550 550 550 GLY GLY D . n 
D 1 551 PHE 551 551 551 PHE PHE D . n 
D 1 552 ALA 552 552 552 ALA ALA D . n 
D 1 553 VAL 553 553 553 VAL VAL D . n 
D 1 554 ALA 554 554 554 ALA ALA D . n 
D 1 555 LEU 555 555 555 LEU LEU D . n 
D 1 556 VAL 556 556 556 VAL VAL D . n 
D 1 557 SER 557 557 557 SER SER D . n 
D 1 558 LEU 558 558 558 LEU LEU D . n 
D 1 559 SER 559 559 559 SER SER D . n 
D 1 560 ARG 560 560 560 ARG ARG D . n 
D 1 561 GLU 561 561 561 GLU GLU D . n 
D 1 562 ALA 562 562 562 ALA ALA D . n 
D 1 563 ARG 563 563 563 ARG ARG D . n 
D 1 564 SER 564 564 ?   ?   ?   D . n 
D 1 565 PRO 565 565 ?   ?   ?   D . n 
D 1 566 LYS 566 566 ?   ?   ?   D . n 
D 1 567 ALA 567 567 ?   ?   ?   D . n 
D 1 568 PRO 568 568 ?   ?   ?   D . n 
D 1 569 GLU 569 569 ?   ?   ?   D . n 
D 1 570 ASP 570 570 ?   ?   ?   D . n 
D 1 571 ASN 571 571 ?   ?   ?   D . n 
D 1 572 ASN 572 572 ?   ?   ?   D . n 
D 1 573 SER 573 573 ?   ?   ?   D . n 
D 1 574 THR 574 574 ?   ?   ?   D . n 
D 1 575 VAL 575 575 ?   ?   ?   D . n 
D 1 576 THR 576 576 ?   ?   ?   D . n 
D 1 577 GLU 577 577 ?   ?   ?   D . n 
D 1 578 GLN 578 578 ?   ?   ?   D . n 
D 1 579 PRO 579 579 ?   ?   ?   D . n 
D 1 580 THR 580 580 ?   ?   ?   D . n 
D 1 581 VAL 581 581 ?   ?   ?   D . n 
D 1 582 GLY 582 582 ?   ?   ?   D . n 
D 1 583 GLN 583 583 ?   ?   ?   D . n 
D 1 584 GLU 584 584 ?   ?   ?   D . n 
D 1 585 GLU 585 585 ?   ?   ?   D . n 
D 1 586 GLU 586 586 ?   ?   ?   D . n 
D 1 587 PRO 587 587 ?   ?   ?   D . n 
D 1 588 ALA 588 588 ?   ?   ?   D . n 
D 1 589 PRO 589 589 589 PRO PRO D . n 
D 1 590 TYR 590 590 590 TYR TYR D . n 
D 1 591 ARG 591 591 591 ARG ARG D . n 
D 1 592 SER 592 592 592 SER SER D . n 
D 1 593 ILE 593 593 593 ILE ILE D . n 
D 1 594 LEU 594 594 594 LEU LEU D . n 
D 1 595 ASP 595 595 595 ASP ASP D . n 
D 1 596 ALA 596 596 596 ALA ALA D . n 
D 1 597 SER 597 597 597 SER SER D . n 
D 1 598 LEU 598 598 598 LEU LEU D . n 
D 1 599 GLU 599 599 599 GLU GLU D . n 
D 1 600 LEU 600 600 600 LEU LEU D . n 
D 1 601 PHE 601 601 601 PHE PHE D . n 
D 1 602 LYS 602 602 602 LYS LYS D . n 
D 1 603 PHE 603 603 603 PHE PHE D . n 
D 1 604 THR 604 604 604 THR THR D . n 
D 1 605 ILE 605 605 605 ILE ILE D . n 
D 1 606 GLY 606 606 606 GLY GLY D . n 
D 1 607 MET 607 607 607 MET MET D . n 
D 1 608 GLY 608 608 608 GLY GLY D . n 
D 1 609 GLU 609 609 609 GLU GLU D . n 
D 1 610 LEU 610 610 610 LEU LEU D . n 
D 1 611 ALA 611 611 611 ALA ALA D . n 
D 1 612 PHE 612 612 612 PHE PHE D . n 
D 1 613 GLN 613 613 613 GLN GLN D . n 
D 1 614 GLU 614 614 614 GLU GLU D . n 
D 1 615 GLN 615 615 615 GLN GLN D . n 
D 1 616 LEU 616 616 616 LEU LEU D . n 
D 1 617 ARG 617 617 617 ARG ARG D . n 
D 1 618 PHE 618 618 618 PHE PHE D . n 
D 1 619 ARG 619 619 619 ARG ARG D . n 
D 1 620 GLY 620 620 620 GLY GLY D . n 
D 1 621 VAL 621 621 621 VAL VAL D . n 
D 1 622 VAL 622 622 622 VAL VAL D . n 
D 1 623 LEU 623 623 623 LEU LEU D . n 
D 1 624 LEU 624 624 624 LEU LEU D . n 
D 1 625 LEU 625 625 625 LEU LEU D . n 
D 1 626 LEU 626 626 626 LEU LEU D . n 
D 1 627 LEU 627 627 627 LEU LEU D . n 
D 1 628 ALA 628 628 628 ALA ALA D . n 
D 1 629 TYR 629 629 629 TYR TYR D . n 
D 1 630 VAL 630 630 630 VAL VAL D . n 
D 1 631 LEU 631 631 631 LEU LEU D . n 
D 1 632 LEU 632 632 632 LEU LEU D . n 
D 1 633 THR 633 633 633 THR THR D . n 
D 1 634 TYR 634 634 634 TYR TYR D . n 
D 1 635 VAL 635 635 635 VAL VAL D . n 
D 1 636 LEU 636 636 636 LEU LEU D . n 
D 1 637 LEU 637 637 637 LEU LEU D . n 
D 1 638 LEU 638 638 638 LEU LEU D . n 
D 1 639 ASN 639 639 639 ASN ASN D . n 
D 1 640 MET 640 640 640 MET MET D . n 
D 1 641 LEU 641 641 641 LEU LEU D . n 
D 1 642 ILE 642 642 642 ILE ILE D . n 
D 1 643 ALA 643 643 643 ALA ALA D . n 
D 1 644 LEU 644 644 644 LEU LEU D . n 
D 1 645 MET 645 645 645 MET MET D . n 
D 1 646 SER 646 646 646 SER SER D . n 
D 1 647 GLU 647 647 647 GLU GLU D . n 
D 1 648 THR 648 648 648 THR THR D . n 
D 1 649 VAL 649 649 649 VAL VAL D . n 
D 1 650 ASN 650 650 650 ASN ASN D . n 
D 1 651 HIS 651 651 651 HIS HIS D . n 
D 1 652 VAL 652 652 652 VAL VAL D . n 
D 1 653 ALA 653 653 653 ALA ALA D . n 
D 1 654 ASP 654 654 654 ASP ASP D . n 
D 1 655 ASN 655 655 655 ASN ASN D . n 
D 1 656 SER 656 656 656 SER SER D . n 
D 1 657 TRP 657 657 657 TRP TRP D . n 
D 1 658 SER 658 658 658 SER SER D . n 
D 1 659 ILE 659 659 659 ILE ILE D . n 
D 1 660 TRP 660 660 660 TRP TRP D . n 
D 1 661 LYS 661 661 661 LYS LYS D . n 
D 1 662 LEU 662 662 662 LEU LEU D . n 
D 1 663 GLN 663 663 663 GLN GLN D . n 
D 1 664 LYS 664 664 664 LYS LYS D . n 
D 1 665 ALA 665 665 665 ALA ALA D . n 
D 1 666 ILE 666 666 666 ILE ILE D . n 
D 1 667 SER 667 667 667 SER SER D . n 
D 1 668 VAL 668 668 668 VAL VAL D . n 
D 1 669 LEU 669 669 669 LEU LEU D . n 
D 1 670 GLU 670 670 670 GLU GLU D . n 
D 1 671 MET 671 671 671 MET MET D . n 
D 1 672 GLU 672 672 672 GLU GLU D . n 
D 1 673 ASN 673 673 673 ASN ASN D . n 
D 1 674 GLY 674 674 674 GLY GLY D . n 
D 1 675 TYR 675 675 675 TYR TYR D . n 
D 1 676 TRP 676 676 676 TRP TRP D . n 
D 1 677 TRP 677 677 677 TRP TRP D . n 
D 1 678 CYS 678 678 678 CYS CYS D . n 
D 1 679 ARG 679 679 679 ARG ARG D . n 
D 1 680 ARG 680 680 680 ARG ARG D . n 
D 1 681 LYS 681 681 681 LYS LYS D . n 
D 1 682 LYS 682 682 682 LYS LYS D . n 
D 1 683 HIS 683 683 683 HIS HIS D . n 
D 1 684 ARG 684 684 684 ARG ARG D . n 
D 1 685 GLU 685 685 685 GLU GLU D . n 
D 1 686 GLY 686 686 686 GLY GLY D . n 
D 1 687 ARG 687 687 687 ARG ARG D . n 
D 1 688 LEU 688 688 688 LEU LEU D . n 
D 1 689 LEU 689 689 689 LEU LEU D . n 
D 1 690 LYS 690 690 690 LYS LYS D . n 
D 1 691 VAL 691 691 691 VAL VAL D . n 
D 1 692 GLY 692 692 692 GLY GLY D . n 
D 1 693 THR 693 693 693 THR THR D . n 
D 1 694 ARG 694 694 694 ARG ARG D . n 
D 1 695 GLY 695 695 ?   ?   ?   D . n 
D 1 696 ASP 696 696 ?   ?   ?   D . n 
D 1 697 GLY 697 697 ?   ?   ?   D . n 
D 1 698 THR 698 698 ?   ?   ?   D . n 
D 1 699 PRO 699 699 699 PRO PRO D . n 
D 1 700 ASP 700 700 700 ASP ASP D . n 
D 1 701 GLU 701 701 701 GLU GLU D . n 
D 1 702 ARG 702 702 702 ARG ARG D . n 
D 1 703 TRP 703 703 703 TRP TRP D . n 
D 1 704 CYS 704 704 704 CYS CYS D . n 
D 1 705 PHE 705 705 705 PHE PHE D . n 
D 1 706 ARG 706 706 706 ARG ARG D . n 
D 1 707 VAL 707 707 707 VAL VAL D . n 
D 1 708 GLU 708 708 708 GLU GLU D . n 
D 1 709 GLU 709 709 709 GLU GLU D . n 
D 1 710 VAL 710 710 710 VAL VAL D . n 
D 1 711 ASN 711 711 711 ASN ASN D . n 
D 1 712 TRP 712 712 712 TRP TRP D . n 
D 1 713 ALA 713 713 713 ALA ALA D . n 
D 1 714 ALA 714 714 714 ALA ALA D . n 
D 1 715 TRP 715 715 715 TRP TRP D . n 
D 1 716 GLU 716 716 716 GLU GLU D . n 
D 1 717 LYS 717 717 717 LYS LYS D . n 
D 1 718 THR 718 718 718 THR THR D . n 
D 1 719 LEU 719 719 719 LEU LEU D . n 
D 1 720 PRO 720 720 ?   ?   ?   D . n 
D 1 721 THR 721 721 ?   ?   ?   D . n 
D 1 722 LEU 722 722 ?   ?   ?   D . n 
D 1 723 SER 723 723 ?   ?   ?   D . n 
D 1 724 ALA 724 724 ?   ?   ?   D . n 
D 1 725 ALA 725 725 ?   ?   ?   D . n 
D 1 726 PRO 726 726 ?   ?   ?   D . n 
D 1 727 SER 727 727 ?   ?   ?   D . n 
D 1 728 GLY 728 728 ?   ?   ?   D . n 
D 1 729 PRO 729 729 ?   ?   ?   D . n 
D 1 730 GLY 730 730 ?   ?   ?   D . n 
D 1 731 ILE 731 731 ?   ?   ?   D . n 
D 1 732 THR 732 732 ?   ?   ?   D . n 
D 1 733 GLY 733 733 ?   ?   ?   D . n 
D 1 734 ASN 734 734 ?   ?   ?   D . n 
D 1 735 LYS 735 735 ?   ?   ?   D . n 
D 1 736 LYS 736 736 ?   ?   ?   D . n 
D 1 737 ASN 737 737 ?   ?   ?   D . n 
D 1 738 PRO 738 738 ?   ?   ?   D . n 
D 1 739 THR 739 739 ?   ?   ?   D . n 
D 1 740 SER 740 740 ?   ?   ?   D . n 
D 1 741 LYS 741 741 ?   ?   ?   D . n 
D 1 742 PRO 742 742 ?   ?   ?   D . n 
D 1 743 GLY 743 743 ?   ?   ?   D . n 
D 1 744 LYS 744 744 ?   ?   ?   D . n 
D 1 745 ASN 745 745 ?   ?   ?   D . n 
D 1 746 SER 746 746 ?   ?   ?   D . n 
D 1 747 ALA 747 747 ?   ?   ?   D . n 
D 1 748 SER 748 748 ?   ?   ?   D . n 
D 1 749 GLU 749 749 ?   ?   ?   D . n 
D 1 750 GLU 750 750 ?   ?   ?   D . n 
D 1 751 ASP 751 751 ?   ?   ?   D . n 
D 1 752 HIS 752 752 ?   ?   ?   D . n 
D 1 753 LEU 753 753 ?   ?   ?   D . n 
D 1 754 PRO 754 754 ?   ?   ?   D . n 
D 1 755 LEU 755 755 ?   ?   ?   D . n 
D 1 756 GLN 756 756 ?   ?   ?   D . n 
D 1 757 VAL 757 757 ?   ?   ?   D . n 
D 1 758 LEU 758 758 ?   ?   ?   D . n 
D 1 759 GLN 759 759 ?   ?   ?   D . n 
D 1 760 SER 760 760 ?   ?   ?   D . n 
D 1 761 PRO 761 761 ?   ?   ?   D . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        RTO 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   RTO 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 2 PEX 1 801 802 PEX PEX A . 
F 3 RTO 1 802 804 RTO RTO A . 
G 2 PEX 1 801 802 PEX PEX B . 
H 3 RTO 1 802 804 RTO RTO B . 
I 2 PEX 1 801 802 PEX PEX C . 
J 3 RTO 1 802 804 RTO RTO C . 
K 2 PEX 1 801 802 PEX PEX D . 
L 3 RTO 1 802 804 RTO RTO D . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 A ARG 74  ? CG  ? A ARG 74  CG  
2   1 Y 1 A ARG 74  ? CD  ? A ARG 74  CD  
3   1 Y 1 A ARG 74  ? NE  ? A ARG 74  NE  
4   1 Y 1 A ARG 74  ? CZ  ? A ARG 74  CZ  
5   1 Y 1 A ARG 74  ? NH1 ? A ARG 74  NH1 
6   1 Y 1 A ARG 74  ? NH2 ? A ARG 74  NH2 
7   1 Y 1 A GLU 90  ? CG  ? A GLU 90  CG  
8   1 Y 1 A GLU 90  ? CD  ? A GLU 90  CD  
9   1 Y 1 A GLU 90  ? OE1 ? A GLU 90  OE1 
10  1 Y 1 A GLU 90  ? OE2 ? A GLU 90  OE2 
11  1 Y 1 A GLU 97  ? CG  ? A GLU 97  CG  
12  1 Y 1 A GLU 97  ? CD  ? A GLU 97  CD  
13  1 Y 1 A GLU 97  ? OE1 ? A GLU 97  OE1 
14  1 Y 1 A GLU 97  ? OE2 ? A GLU 97  OE2 
15  1 Y 1 A ASP 130 ? CG  ? A ASP 130 CG  
16  1 Y 1 A ASP 130 ? OD1 ? A ASP 130 OD1 
17  1 Y 1 A ASP 130 ? OD2 ? A ASP 130 OD2 
18  1 Y 1 A GLN 203 ? CG  ? A GLN 203 CG  
19  1 Y 1 A GLN 203 ? CD  ? A GLN 203 CD  
20  1 Y 1 A GLN 203 ? OE1 ? A GLN 203 OE1 
21  1 Y 1 A GLN 203 ? NE2 ? A GLN 203 NE2 
22  1 Y 1 A GLU 262 ? CG  ? A GLU 262 CG  
23  1 Y 1 A GLU 262 ? CD  ? A GLU 262 CD  
24  1 Y 1 A GLU 262 ? OE1 ? A GLU 262 OE1 
25  1 Y 1 A GLU 262 ? OE2 ? A GLU 262 OE2 
26  1 Y 1 A GLU 352 ? CG  ? A GLU 352 CG  
27  1 Y 1 A GLU 352 ? CD  ? A GLU 352 CD  
28  1 Y 1 A GLU 352 ? OE1 ? A GLU 352 OE1 
29  1 Y 1 A GLU 352 ? OE2 ? A GLU 352 OE2 
30  1 Y 1 A GLU 431 ? CG  ? A GLU 431 CG  
31  1 Y 1 A GLU 431 ? CD  ? A GLU 431 CD  
32  1 Y 1 A GLU 431 ? OE1 ? A GLU 431 OE1 
33  1 Y 1 A GLU 431 ? OE2 ? A GLU 431 OE2 
34  1 Y 1 A TRP 464 ? CG  ? A TRP 464 CG  
35  1 Y 1 A TRP 464 ? CD1 ? A TRP 464 CD1 
36  1 Y 1 A TRP 464 ? CD2 ? A TRP 464 CD2 
37  1 Y 1 A TRP 464 ? NE1 ? A TRP 464 NE1 
38  1 Y 1 A TRP 464 ? CE2 ? A TRP 464 CE2 
39  1 Y 1 A TRP 464 ? CE3 ? A TRP 464 CE3 
40  1 Y 1 A TRP 464 ? CZ2 ? A TRP 464 CZ2 
41  1 Y 1 A TRP 464 ? CZ3 ? A TRP 464 CZ3 
42  1 Y 1 A TRP 464 ? CH2 ? A TRP 464 CH2 
43  1 Y 1 A PHE 491 ? CG  ? A PHE 491 CG  
44  1 Y 1 A PHE 491 ? CD1 ? A PHE 491 CD1 
45  1 Y 1 A PHE 491 ? CD2 ? A PHE 491 CD2 
46  1 Y 1 A PHE 491 ? CE1 ? A PHE 491 CE1 
47  1 Y 1 A PHE 491 ? CE2 ? A PHE 491 CE2 
48  1 Y 1 A PHE 491 ? CZ  ? A PHE 491 CZ  
49  1 Y 1 A GLU 493 ? CG  ? A GLU 493 CG  
50  1 Y 1 A GLU 493 ? CD  ? A GLU 493 CD  
51  1 Y 1 A GLU 493 ? OE1 ? A GLU 493 OE1 
52  1 Y 1 A GLU 493 ? OE2 ? A GLU 493 OE2 
53  1 Y 1 A GLU 495 ? CG  ? A GLU 495 CG  
54  1 Y 1 A GLU 495 ? CD  ? A GLU 495 CD  
55  1 Y 1 A GLU 495 ? OE1 ? A GLU 495 OE1 
56  1 Y 1 A GLU 495 ? OE2 ? A GLU 495 OE2 
57  1 Y 1 A ARG 563 ? CG  ? A ARG 563 CG  
58  1 Y 1 A ARG 563 ? CD  ? A ARG 563 CD  
59  1 Y 1 A ARG 563 ? NE  ? A ARG 563 NE  
60  1 Y 1 A ARG 563 ? CZ  ? A ARG 563 CZ  
61  1 Y 1 A ARG 563 ? NH1 ? A ARG 563 NH1 
62  1 Y 1 A ARG 563 ? NH2 ? A ARG 563 NH2 
63  1 Y 1 A ARG 591 ? CG  ? A ARG 591 CG  
64  1 Y 1 A ARG 591 ? CD  ? A ARG 591 CD  
65  1 Y 1 A ARG 591 ? NE  ? A ARG 591 NE  
66  1 Y 1 A ARG 591 ? CZ  ? A ARG 591 CZ  
67  1 Y 1 A ARG 591 ? NH1 ? A ARG 591 NH1 
68  1 Y 1 A ARG 591 ? NH2 ? A ARG 591 NH2 
69  1 Y 1 A GLU 614 ? CG  ? A GLU 614 CG  
70  1 Y 1 A GLU 614 ? CD  ? A GLU 614 CD  
71  1 Y 1 A GLU 614 ? OE1 ? A GLU 614 OE1 
72  1 Y 1 A GLU 614 ? OE2 ? A GLU 614 OE2 
73  1 Y 1 A LYS 681 ? CG  ? A LYS 681 CG  
74  1 Y 1 A LYS 681 ? CD  ? A LYS 681 CD  
75  1 Y 1 A LYS 681 ? CE  ? A LYS 681 CE  
76  1 Y 1 A LYS 681 ? NZ  ? A LYS 681 NZ  
77  1 Y 1 B ARG 74  ? CG  ? B ARG 74  CG  
78  1 Y 1 B ARG 74  ? CD  ? B ARG 74  CD  
79  1 Y 1 B ARG 74  ? NE  ? B ARG 74  NE  
80  1 Y 1 B ARG 74  ? CZ  ? B ARG 74  CZ  
81  1 Y 1 B ARG 74  ? NH1 ? B ARG 74  NH1 
82  1 Y 1 B ARG 74  ? NH2 ? B ARG 74  NH2 
83  1 Y 1 B GLU 90  ? CG  ? B GLU 90  CG  
84  1 Y 1 B GLU 90  ? CD  ? B GLU 90  CD  
85  1 Y 1 B GLU 90  ? OE1 ? B GLU 90  OE1 
86  1 Y 1 B GLU 90  ? OE2 ? B GLU 90  OE2 
87  1 Y 1 B GLU 97  ? CG  ? B GLU 97  CG  
88  1 Y 1 B GLU 97  ? CD  ? B GLU 97  CD  
89  1 Y 1 B GLU 97  ? OE1 ? B GLU 97  OE1 
90  1 Y 1 B GLU 97  ? OE2 ? B GLU 97  OE2 
91  1 Y 1 B ASP 130 ? CG  ? B ASP 130 CG  
92  1 Y 1 B ASP 130 ? OD1 ? B ASP 130 OD1 
93  1 Y 1 B ASP 130 ? OD2 ? B ASP 130 OD2 
94  1 Y 1 B GLN 203 ? CG  ? B GLN 203 CG  
95  1 Y 1 B GLN 203 ? CD  ? B GLN 203 CD  
96  1 Y 1 B GLN 203 ? OE1 ? B GLN 203 OE1 
97  1 Y 1 B GLN 203 ? NE2 ? B GLN 203 NE2 
98  1 Y 1 B GLU 262 ? CG  ? B GLU 262 CG  
99  1 Y 1 B GLU 262 ? CD  ? B GLU 262 CD  
100 1 Y 1 B GLU 262 ? OE1 ? B GLU 262 OE1 
101 1 Y 1 B GLU 262 ? OE2 ? B GLU 262 OE2 
102 1 Y 1 B GLU 352 ? CG  ? B GLU 352 CG  
103 1 Y 1 B GLU 352 ? CD  ? B GLU 352 CD  
104 1 Y 1 B GLU 352 ? OE1 ? B GLU 352 OE1 
105 1 Y 1 B GLU 352 ? OE2 ? B GLU 352 OE2 
106 1 Y 1 B GLU 431 ? CG  ? B GLU 431 CG  
107 1 Y 1 B GLU 431 ? CD  ? B GLU 431 CD  
108 1 Y 1 B GLU 431 ? OE1 ? B GLU 431 OE1 
109 1 Y 1 B GLU 431 ? OE2 ? B GLU 431 OE2 
110 1 Y 1 B TRP 464 ? CG  ? B TRP 464 CG  
111 1 Y 1 B TRP 464 ? CD1 ? B TRP 464 CD1 
112 1 Y 1 B TRP 464 ? CD2 ? B TRP 464 CD2 
113 1 Y 1 B TRP 464 ? NE1 ? B TRP 464 NE1 
114 1 Y 1 B TRP 464 ? CE2 ? B TRP 464 CE2 
115 1 Y 1 B TRP 464 ? CE3 ? B TRP 464 CE3 
116 1 Y 1 B TRP 464 ? CZ2 ? B TRP 464 CZ2 
117 1 Y 1 B TRP 464 ? CZ3 ? B TRP 464 CZ3 
118 1 Y 1 B TRP 464 ? CH2 ? B TRP 464 CH2 
119 1 Y 1 B PHE 491 ? CG  ? B PHE 491 CG  
120 1 Y 1 B PHE 491 ? CD1 ? B PHE 491 CD1 
121 1 Y 1 B PHE 491 ? CD2 ? B PHE 491 CD2 
122 1 Y 1 B PHE 491 ? CE1 ? B PHE 491 CE1 
123 1 Y 1 B PHE 491 ? CE2 ? B PHE 491 CE2 
124 1 Y 1 B PHE 491 ? CZ  ? B PHE 491 CZ  
125 1 Y 1 B GLU 493 ? CG  ? B GLU 493 CG  
126 1 Y 1 B GLU 493 ? CD  ? B GLU 493 CD  
127 1 Y 1 B GLU 493 ? OE1 ? B GLU 493 OE1 
128 1 Y 1 B GLU 493 ? OE2 ? B GLU 493 OE2 
129 1 Y 1 B GLU 495 ? CG  ? B GLU 495 CG  
130 1 Y 1 B GLU 495 ? CD  ? B GLU 495 CD  
131 1 Y 1 B GLU 495 ? OE1 ? B GLU 495 OE1 
132 1 Y 1 B GLU 495 ? OE2 ? B GLU 495 OE2 
133 1 Y 1 B ARG 563 ? CG  ? B ARG 563 CG  
134 1 Y 1 B ARG 563 ? CD  ? B ARG 563 CD  
135 1 Y 1 B ARG 563 ? NE  ? B ARG 563 NE  
136 1 Y 1 B ARG 563 ? CZ  ? B ARG 563 CZ  
137 1 Y 1 B ARG 563 ? NH1 ? B ARG 563 NH1 
138 1 Y 1 B ARG 563 ? NH2 ? B ARG 563 NH2 
139 1 Y 1 B ARG 591 ? CG  ? B ARG 591 CG  
140 1 Y 1 B ARG 591 ? CD  ? B ARG 591 CD  
141 1 Y 1 B ARG 591 ? NE  ? B ARG 591 NE  
142 1 Y 1 B ARG 591 ? CZ  ? B ARG 591 CZ  
143 1 Y 1 B ARG 591 ? NH1 ? B ARG 591 NH1 
144 1 Y 1 B ARG 591 ? NH2 ? B ARG 591 NH2 
145 1 Y 1 B GLU 614 ? CG  ? B GLU 614 CG  
146 1 Y 1 B GLU 614 ? CD  ? B GLU 614 CD  
147 1 Y 1 B GLU 614 ? OE1 ? B GLU 614 OE1 
148 1 Y 1 B GLU 614 ? OE2 ? B GLU 614 OE2 
149 1 Y 1 B LYS 681 ? CG  ? B LYS 681 CG  
150 1 Y 1 B LYS 681 ? CD  ? B LYS 681 CD  
151 1 Y 1 B LYS 681 ? CE  ? B LYS 681 CE  
152 1 Y 1 B LYS 681 ? NZ  ? B LYS 681 NZ  
153 1 Y 1 C ARG 74  ? CG  ? C ARG 74  CG  
154 1 Y 1 C ARG 74  ? CD  ? C ARG 74  CD  
155 1 Y 1 C ARG 74  ? NE  ? C ARG 74  NE  
156 1 Y 1 C ARG 74  ? CZ  ? C ARG 74  CZ  
157 1 Y 1 C ARG 74  ? NH1 ? C ARG 74  NH1 
158 1 Y 1 C ARG 74  ? NH2 ? C ARG 74  NH2 
159 1 Y 1 C GLU 90  ? CG  ? C GLU 90  CG  
160 1 Y 1 C GLU 90  ? CD  ? C GLU 90  CD  
161 1 Y 1 C GLU 90  ? OE1 ? C GLU 90  OE1 
162 1 Y 1 C GLU 90  ? OE2 ? C GLU 90  OE2 
163 1 Y 1 C GLU 97  ? CG  ? C GLU 97  CG  
164 1 Y 1 C GLU 97  ? CD  ? C GLU 97  CD  
165 1 Y 1 C GLU 97  ? OE1 ? C GLU 97  OE1 
166 1 Y 1 C GLU 97  ? OE2 ? C GLU 97  OE2 
167 1 Y 1 C ASP 130 ? CG  ? C ASP 130 CG  
168 1 Y 1 C ASP 130 ? OD1 ? C ASP 130 OD1 
169 1 Y 1 C ASP 130 ? OD2 ? C ASP 130 OD2 
170 1 Y 1 C GLN 203 ? CG  ? C GLN 203 CG  
171 1 Y 1 C GLN 203 ? CD  ? C GLN 203 CD  
172 1 Y 1 C GLN 203 ? OE1 ? C GLN 203 OE1 
173 1 Y 1 C GLN 203 ? NE2 ? C GLN 203 NE2 
174 1 Y 1 C GLU 262 ? CG  ? C GLU 262 CG  
175 1 Y 1 C GLU 262 ? CD  ? C GLU 262 CD  
176 1 Y 1 C GLU 262 ? OE1 ? C GLU 262 OE1 
177 1 Y 1 C GLU 262 ? OE2 ? C GLU 262 OE2 
178 1 Y 1 C GLU 352 ? CG  ? C GLU 352 CG  
179 1 Y 1 C GLU 352 ? CD  ? C GLU 352 CD  
180 1 Y 1 C GLU 352 ? OE1 ? C GLU 352 OE1 
181 1 Y 1 C GLU 352 ? OE2 ? C GLU 352 OE2 
182 1 Y 1 C GLU 431 ? CG  ? C GLU 431 CG  
183 1 Y 1 C GLU 431 ? CD  ? C GLU 431 CD  
184 1 Y 1 C GLU 431 ? OE1 ? C GLU 431 OE1 
185 1 Y 1 C GLU 431 ? OE2 ? C GLU 431 OE2 
186 1 Y 1 C TRP 464 ? CG  ? C TRP 464 CG  
187 1 Y 1 C TRP 464 ? CD1 ? C TRP 464 CD1 
188 1 Y 1 C TRP 464 ? CD2 ? C TRP 464 CD2 
189 1 Y 1 C TRP 464 ? NE1 ? C TRP 464 NE1 
190 1 Y 1 C TRP 464 ? CE2 ? C TRP 464 CE2 
191 1 Y 1 C TRP 464 ? CE3 ? C TRP 464 CE3 
192 1 Y 1 C TRP 464 ? CZ2 ? C TRP 464 CZ2 
193 1 Y 1 C TRP 464 ? CZ3 ? C TRP 464 CZ3 
194 1 Y 1 C TRP 464 ? CH2 ? C TRP 464 CH2 
195 1 Y 1 C PHE 491 ? CG  ? C PHE 491 CG  
196 1 Y 1 C PHE 491 ? CD1 ? C PHE 491 CD1 
197 1 Y 1 C PHE 491 ? CD2 ? C PHE 491 CD2 
198 1 Y 1 C PHE 491 ? CE1 ? C PHE 491 CE1 
199 1 Y 1 C PHE 491 ? CE2 ? C PHE 491 CE2 
200 1 Y 1 C PHE 491 ? CZ  ? C PHE 491 CZ  
201 1 Y 1 C GLU 493 ? CG  ? C GLU 493 CG  
202 1 Y 1 C GLU 493 ? CD  ? C GLU 493 CD  
203 1 Y 1 C GLU 493 ? OE1 ? C GLU 493 OE1 
204 1 Y 1 C GLU 493 ? OE2 ? C GLU 493 OE2 
205 1 Y 1 C GLU 495 ? CG  ? C GLU 495 CG  
206 1 Y 1 C GLU 495 ? CD  ? C GLU 495 CD  
207 1 Y 1 C GLU 495 ? OE1 ? C GLU 495 OE1 
208 1 Y 1 C GLU 495 ? OE2 ? C GLU 495 OE2 
209 1 Y 1 C ARG 563 ? CG  ? C ARG 563 CG  
210 1 Y 1 C ARG 563 ? CD  ? C ARG 563 CD  
211 1 Y 1 C ARG 563 ? NE  ? C ARG 563 NE  
212 1 Y 1 C ARG 563 ? CZ  ? C ARG 563 CZ  
213 1 Y 1 C ARG 563 ? NH1 ? C ARG 563 NH1 
214 1 Y 1 C ARG 563 ? NH2 ? C ARG 563 NH2 
215 1 Y 1 C ARG 591 ? CG  ? C ARG 591 CG  
216 1 Y 1 C ARG 591 ? CD  ? C ARG 591 CD  
217 1 Y 1 C ARG 591 ? NE  ? C ARG 591 NE  
218 1 Y 1 C ARG 591 ? CZ  ? C ARG 591 CZ  
219 1 Y 1 C ARG 591 ? NH1 ? C ARG 591 NH1 
220 1 Y 1 C ARG 591 ? NH2 ? C ARG 591 NH2 
221 1 Y 1 C GLU 614 ? CG  ? C GLU 614 CG  
222 1 Y 1 C GLU 614 ? CD  ? C GLU 614 CD  
223 1 Y 1 C GLU 614 ? OE1 ? C GLU 614 OE1 
224 1 Y 1 C GLU 614 ? OE2 ? C GLU 614 OE2 
225 1 Y 1 C LYS 681 ? CG  ? C LYS 681 CG  
226 1 Y 1 C LYS 681 ? CD  ? C LYS 681 CD  
227 1 Y 1 C LYS 681 ? CE  ? C LYS 681 CE  
228 1 Y 1 C LYS 681 ? NZ  ? C LYS 681 NZ  
229 1 Y 1 D ARG 74  ? CG  ? D ARG 74  CG  
230 1 Y 1 D ARG 74  ? CD  ? D ARG 74  CD  
231 1 Y 1 D ARG 74  ? NE  ? D ARG 74  NE  
232 1 Y 1 D ARG 74  ? CZ  ? D ARG 74  CZ  
233 1 Y 1 D ARG 74  ? NH1 ? D ARG 74  NH1 
234 1 Y 1 D ARG 74  ? NH2 ? D ARG 74  NH2 
235 1 Y 1 D GLU 90  ? CG  ? D GLU 90  CG  
236 1 Y 1 D GLU 90  ? CD  ? D GLU 90  CD  
237 1 Y 1 D GLU 90  ? OE1 ? D GLU 90  OE1 
238 1 Y 1 D GLU 90  ? OE2 ? D GLU 90  OE2 
239 1 Y 1 D GLU 97  ? CG  ? D GLU 97  CG  
240 1 Y 1 D GLU 97  ? CD  ? D GLU 97  CD  
241 1 Y 1 D GLU 97  ? OE1 ? D GLU 97  OE1 
242 1 Y 1 D GLU 97  ? OE2 ? D GLU 97  OE2 
243 1 Y 1 D ASP 130 ? CG  ? D ASP 130 CG  
244 1 Y 1 D ASP 130 ? OD1 ? D ASP 130 OD1 
245 1 Y 1 D ASP 130 ? OD2 ? D ASP 130 OD2 
246 1 Y 1 D GLN 203 ? CG  ? D GLN 203 CG  
247 1 Y 1 D GLN 203 ? CD  ? D GLN 203 CD  
248 1 Y 1 D GLN 203 ? OE1 ? D GLN 203 OE1 
249 1 Y 1 D GLN 203 ? NE2 ? D GLN 203 NE2 
250 1 Y 1 D GLU 262 ? CG  ? D GLU 262 CG  
251 1 Y 1 D GLU 262 ? CD  ? D GLU 262 CD  
252 1 Y 1 D GLU 262 ? OE1 ? D GLU 262 OE1 
253 1 Y 1 D GLU 262 ? OE2 ? D GLU 262 OE2 
254 1 Y 1 D GLU 352 ? CG  ? D GLU 352 CG  
255 1 Y 1 D GLU 352 ? CD  ? D GLU 352 CD  
256 1 Y 1 D GLU 352 ? OE1 ? D GLU 352 OE1 
257 1 Y 1 D GLU 352 ? OE2 ? D GLU 352 OE2 
258 1 Y 1 D GLU 431 ? CG  ? D GLU 431 CG  
259 1 Y 1 D GLU 431 ? CD  ? D GLU 431 CD  
260 1 Y 1 D GLU 431 ? OE1 ? D GLU 431 OE1 
261 1 Y 1 D GLU 431 ? OE2 ? D GLU 431 OE2 
262 1 Y 1 D TRP 464 ? CG  ? D TRP 464 CG  
263 1 Y 1 D TRP 464 ? CD1 ? D TRP 464 CD1 
264 1 Y 1 D TRP 464 ? CD2 ? D TRP 464 CD2 
265 1 Y 1 D TRP 464 ? NE1 ? D TRP 464 NE1 
266 1 Y 1 D TRP 464 ? CE2 ? D TRP 464 CE2 
267 1 Y 1 D TRP 464 ? CE3 ? D TRP 464 CE3 
268 1 Y 1 D TRP 464 ? CZ2 ? D TRP 464 CZ2 
269 1 Y 1 D TRP 464 ? CZ3 ? D TRP 464 CZ3 
270 1 Y 1 D TRP 464 ? CH2 ? D TRP 464 CH2 
271 1 Y 1 D PHE 491 ? CG  ? D PHE 491 CG  
272 1 Y 1 D PHE 491 ? CD1 ? D PHE 491 CD1 
273 1 Y 1 D PHE 491 ? CD2 ? D PHE 491 CD2 
274 1 Y 1 D PHE 491 ? CE1 ? D PHE 491 CE1 
275 1 Y 1 D PHE 491 ? CE2 ? D PHE 491 CE2 
276 1 Y 1 D PHE 491 ? CZ  ? D PHE 491 CZ  
277 1 Y 1 D GLU 493 ? CG  ? D GLU 493 CG  
278 1 Y 1 D GLU 493 ? CD  ? D GLU 493 CD  
279 1 Y 1 D GLU 493 ? OE1 ? D GLU 493 OE1 
280 1 Y 1 D GLU 493 ? OE2 ? D GLU 493 OE2 
281 1 Y 1 D GLU 495 ? CG  ? D GLU 495 CG  
282 1 Y 1 D GLU 495 ? CD  ? D GLU 495 CD  
283 1 Y 1 D GLU 495 ? OE1 ? D GLU 495 OE1 
284 1 Y 1 D GLU 495 ? OE2 ? D GLU 495 OE2 
285 1 Y 1 D ARG 563 ? CG  ? D ARG 563 CG  
286 1 Y 1 D ARG 563 ? CD  ? D ARG 563 CD  
287 1 Y 1 D ARG 563 ? NE  ? D ARG 563 NE  
288 1 Y 1 D ARG 563 ? CZ  ? D ARG 563 CZ  
289 1 Y 1 D ARG 563 ? NH1 ? D ARG 563 NH1 
290 1 Y 1 D ARG 563 ? NH2 ? D ARG 563 NH2 
291 1 Y 1 D ARG 591 ? CG  ? D ARG 591 CG  
292 1 Y 1 D ARG 591 ? CD  ? D ARG 591 CD  
293 1 Y 1 D ARG 591 ? NE  ? D ARG 591 NE  
294 1 Y 1 D ARG 591 ? CZ  ? D ARG 591 CZ  
295 1 Y 1 D ARG 591 ? NH1 ? D ARG 591 NH1 
296 1 Y 1 D ARG 591 ? NH2 ? D ARG 591 NH2 
297 1 Y 1 D GLU 614 ? CG  ? D GLU 614 CG  
298 1 Y 1 D GLU 614 ? CD  ? D GLU 614 CD  
299 1 Y 1 D GLU 614 ? OE1 ? D GLU 614 OE1 
300 1 Y 1 D GLU 614 ? OE2 ? D GLU 614 OE2 
301 1 Y 1 D LYS 681 ? CG  ? D LYS 681 CG  
302 1 Y 1 D LYS 681 ? CD  ? D LYS 681 CD  
303 1 Y 1 D LYS 681 ? CE  ? D LYS 681 CE  
304 1 Y 1 D LYS 681 ? NZ  ? D LYS 681 NZ  
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9B3Y 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9B3Y 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9B3Y 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9B3Y 
_struct.title                        'Rat TRPV2 E724A/D725A bound to probenecid' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9B3Y 
_struct_keywords.text            'TRPV2, TRP channel, probenecid, 2-APB, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 2 ? 
F N N 3 ? 
G N N 2 ? 
H N N 3 ? 
I N N 2 ? 
J N N 3 ? 
K N N 2 ? 
L N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    TRPV2_RAT 
_struct_ref.pdbx_db_accession          Q9WUD2 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MTSASSPPAFRLETSDGDEEGNAEVNKGKQEPPPMESPFQREDRNSSPQIKVNLNFIKRPPKNTSAPSQQEPDRFDRDRL
FSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDE
FYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLE
ATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFS
GPYQPLSRKFTEWCYGPVRVSLYDLSSVDSWEKNSVLEIIAFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNFACY
LVYMFIFTVVAYHQPSLDQPAIPSSKATFGESMLLLGHILILLGGIYLLLGQLWYFWRRRLFIWISFMDSYFEILFLLQA
LLTVLSQVLRFMETEWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSR
EARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNM
LIALMSETVNHVADNSWSIWKLQKAISVLEMENGYWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEEVNWAAWEKTLP
TLSEDPSGPGITGNKKNPTSKPGKNSASEEDHLPLQVLQSP
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9B3Y A 1 ? 761 ? Q9WUD2 1 ? 761 ? 1 761 
2 1 9B3Y B 1 ? 761 ? Q9WUD2 1 ? 761 ? 1 761 
3 1 9B3Y C 1 ? 761 ? Q9WUD2 1 ? 761 ? 1 761 
4 1 9B3Y D 1 ? 761 ? Q9WUD2 1 ? 761 ? 1 761 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9B3Y ALA A 724 ? UNP Q9WUD2 GLU 724 'engineered mutation' 724 1 
1 9B3Y ALA A 725 ? UNP Q9WUD2 ASP 725 'engineered mutation' 725 2 
2 9B3Y ALA B 724 ? UNP Q9WUD2 GLU 724 'engineered mutation' 724 3 
2 9B3Y ALA B 725 ? UNP Q9WUD2 ASP 725 'engineered mutation' 725 4 
3 9B3Y ALA C 724 ? UNP Q9WUD2 GLU 724 'engineered mutation' 724 5 
3 9B3Y ALA C 725 ? UNP Q9WUD2 ASP 725 'engineered mutation' 725 6 
4 9B3Y ALA D 724 ? UNP Q9WUD2 GLU 724 'engineered mutation' 724 7 
4 9B3Y ALA D 725 ? UNP Q9WUD2 ASP 725 'engineered mutation' 725 8 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1   AA1 ASP A 76  ? GLY A 87  ? ASP A 76  GLY A 87  1 ? 12 
HELX_P HELX_P2   AA2 PRO A 89  ? THR A 93  ? PRO A 89  THR A 93  5 ? 5  
HELX_P HELX_P3   AA3 GLY A 94  ? SER A 103 ? GLY A 94  SER A 103 1 ? 10 
HELX_P HELX_P4   AA4 ASP A 108 ? THR A 112 ? ASP A 108 THR A 112 5 ? 5  
HELX_P HELX_P5   AA5 THR A 119 ? LEU A 126 ? THR A 119 LEU A 126 1 ? 8  
HELX_P HELX_P6   AA6 CYS A 135 ? GLY A 147 ? CYS A 135 GLY A 147 1 ? 13 
HELX_P HELX_P7   AA7 SER A 166 ? LYS A 174 ? SER A 166 LYS A 174 1 ? 9  
HELX_P HELX_P8   AA8 SER A 176 ? ASN A 186 ? SER A 176 ASN A 186 1 ? 11 
HELX_P HELX_P9   AA9 LEU A 212 ? THR A 220 ? LEU A 212 THR A 220 1 ? 9  
HELX_P HELX_P10  AB1 GLN A 222 ? ASN A 232 ? GLN A 222 ASN A 232 1 ? 11 
HELX_P HELX_P11  AB2 THR A 248 ? ALA A 257 ? THR A 248 ALA A 257 1 ? 10 
HELX_P HELX_P12  AB3 SER A 260 ? CYS A 282 ? SER A 260 CYS A 282 1 ? 23 
HELX_P HELX_P13  AB4 GLN A 286 ? ILE A 290 ? GLN A 286 ILE A 290 5 ? 5  
HELX_P HELX_P14  AB5 THR A 297 ? GLU A 305 ? THR A 297 GLU A 305 1 ? 9  
HELX_P HELX_P15  AB6 LYS A 307 ? GLN A 316 ? LYS A 307 GLN A 316 1 ? 10 
HELX_P HELX_P16  AB7 SER A 320 ? SER A 327 ? SER A 320 SER A 327 5 ? 8  
HELX_P HELX_P17  AB8 SER A 355 ? HIS A 363 ? SER A 355 HIS A 363 1 ? 9  
HELX_P HELX_P18  AB9 ASN A 368 ? VAL A 373 ? ASN A 368 VAL A 373 1 ? 6  
HELX_P HELX_P19  AC1 PRO A 377 ? TYR A 412 ? PRO A 377 TYR A 412 1 ? 36 
HELX_P HELX_P20  AC2 GLY A 430 ? ARG A 459 ? GLY A 430 ARG A 459 1 ? 30 
HELX_P HELX_P21  AC3 ARG A 460 ? ILE A 463 ? ARG A 460 ILE A 463 5 ? 4  
HELX_P HELX_P22  AC4 TYR A 471 ? MET A 492 ? TYR A 471 MET A 492 1 ? 22 
HELX_P HELX_P23  AC5 TRP A 496 ? ASN A 511 ? TRP A 496 ASN A 511 1 ? 16 
HELX_P HELX_P24  AC6 LEU A 512 ? GLY A 518 ? LEU A 512 GLY A 518 5 ? 7  
HELX_P HELX_P25  AC7 PHE A 519 ? GLN A 530 ? PHE A 519 GLN A 530 1 ? 12 
HELX_P HELX_P26  AC8 VAL A 532 ? SER A 559 ? VAL A 532 SER A 559 1 ? 28 
HELX_P HELX_P27  AC9 SER A 592 ? PHE A 603 ? SER A 592 PHE A 603 1 ? 12 
HELX_P HELX_P28  AD1 PHE A 618 ? VAL A 649 ? PHE A 618 VAL A 649 1 ? 32 
HELX_P HELX_P29  AD2 ASN A 655 ? GLU A 672 ? ASN A 655 GLU A 672 1 ? 18 
HELX_P HELX_P30  AD3 ASN A 711 ? LYS A 717 ? ASN A 711 LYS A 717 1 ? 7  
HELX_P HELX_P31  AD4 ASP B 76  ? GLY B 87  ? ASP B 76  GLY B 87  1 ? 12 
HELX_P HELX_P32  AD5 PRO B 89  ? THR B 93  ? PRO B 89  THR B 93  5 ? 5  
HELX_P HELX_P33  AD6 GLY B 94  ? SER B 103 ? GLY B 94  SER B 103 1 ? 10 
HELX_P HELX_P34  AD7 ASP B 108 ? THR B 112 ? ASP B 108 THR B 112 5 ? 5  
HELX_P HELX_P35  AD8 THR B 119 ? LEU B 126 ? THR B 119 LEU B 126 1 ? 8  
HELX_P HELX_P36  AD9 CYS B 135 ? GLY B 147 ? CYS B 135 GLY B 147 1 ? 13 
HELX_P HELX_P37  AE1 SER B 166 ? LYS B 174 ? SER B 166 LYS B 174 1 ? 9  
HELX_P HELX_P38  AE2 SER B 176 ? ASN B 186 ? SER B 176 ASN B 186 1 ? 11 
HELX_P HELX_P39  AE3 LEU B 212 ? THR B 220 ? LEU B 212 THR B 220 1 ? 9  
HELX_P HELX_P40  AE4 GLN B 222 ? ASN B 232 ? GLN B 222 ASN B 232 1 ? 11 
HELX_P HELX_P41  AE5 THR B 248 ? ALA B 257 ? THR B 248 ALA B 257 1 ? 10 
HELX_P HELX_P42  AE6 SER B 260 ? CYS B 282 ? SER B 260 CYS B 282 1 ? 23 
HELX_P HELX_P43  AE7 GLN B 286 ? ILE B 290 ? GLN B 286 ILE B 290 5 ? 5  
HELX_P HELX_P44  AE8 THR B 297 ? GLU B 305 ? THR B 297 GLU B 305 1 ? 9  
HELX_P HELX_P45  AE9 LYS B 307 ? GLN B 316 ? LYS B 307 GLN B 316 1 ? 10 
HELX_P HELX_P46  AF1 SER B 320 ? SER B 327 ? SER B 320 SER B 327 5 ? 8  
HELX_P HELX_P47  AF2 SER B 355 ? HIS B 363 ? SER B 355 HIS B 363 1 ? 9  
HELX_P HELX_P48  AF3 ASN B 368 ? VAL B 373 ? ASN B 368 VAL B 373 1 ? 6  
HELX_P HELX_P49  AF4 PRO B 377 ? TYR B 412 ? PRO B 377 TYR B 412 1 ? 36 
HELX_P HELX_P50  AF5 GLY B 430 ? ARG B 459 ? GLY B 430 ARG B 459 1 ? 30 
HELX_P HELX_P51  AF6 ARG B 460 ? ILE B 463 ? ARG B 460 ILE B 463 5 ? 4  
HELX_P HELX_P52  AF7 TYR B 471 ? MET B 492 ? TYR B 471 MET B 492 1 ? 22 
HELX_P HELX_P53  AF8 TRP B 496 ? ASN B 511 ? TRP B 496 ASN B 511 1 ? 16 
HELX_P HELX_P54  AF9 LEU B 512 ? GLY B 518 ? LEU B 512 GLY B 518 5 ? 7  
HELX_P HELX_P55  AG1 PHE B 519 ? GLN B 530 ? PHE B 519 GLN B 530 1 ? 12 
HELX_P HELX_P56  AG2 VAL B 532 ? SER B 559 ? VAL B 532 SER B 559 1 ? 28 
HELX_P HELX_P57  AG3 SER B 592 ? PHE B 603 ? SER B 592 PHE B 603 1 ? 12 
HELX_P HELX_P58  AG4 PHE B 618 ? VAL B 649 ? PHE B 618 VAL B 649 1 ? 32 
HELX_P HELX_P59  AG5 ASN B 655 ? GLU B 672 ? ASN B 655 GLU B 672 1 ? 18 
HELX_P HELX_P60  AG6 ASN B 711 ? LYS B 717 ? ASN B 711 LYS B 717 1 ? 7  
HELX_P HELX_P61  AG7 ASP C 76  ? GLY C 87  ? ASP C 76  GLY C 87  1 ? 12 
HELX_P HELX_P62  AG8 PRO C 89  ? THR C 93  ? PRO C 89  THR C 93  5 ? 5  
HELX_P HELX_P63  AG9 GLY C 94  ? SER C 103 ? GLY C 94  SER C 103 1 ? 10 
HELX_P HELX_P64  AH1 ASP C 108 ? THR C 112 ? ASP C 108 THR C 112 5 ? 5  
HELX_P HELX_P65  AH2 THR C 119 ? LEU C 126 ? THR C 119 LEU C 126 1 ? 8  
HELX_P HELX_P66  AH3 CYS C 135 ? GLY C 147 ? CYS C 135 GLY C 147 1 ? 13 
HELX_P HELX_P67  AH4 SER C 166 ? LYS C 174 ? SER C 166 LYS C 174 1 ? 9  
HELX_P HELX_P68  AH5 SER C 176 ? ASN C 186 ? SER C 176 ASN C 186 1 ? 11 
HELX_P HELX_P69  AH6 LEU C 212 ? THR C 220 ? LEU C 212 THR C 220 1 ? 9  
HELX_P HELX_P70  AH7 GLN C 222 ? ASN C 232 ? GLN C 222 ASN C 232 1 ? 11 
HELX_P HELX_P71  AH8 THR C 248 ? ALA C 257 ? THR C 248 ALA C 257 1 ? 10 
HELX_P HELX_P72  AH9 SER C 260 ? CYS C 282 ? SER C 260 CYS C 282 1 ? 23 
HELX_P HELX_P73  AI1 GLN C 286 ? ILE C 290 ? GLN C 286 ILE C 290 5 ? 5  
HELX_P HELX_P74  AI2 THR C 297 ? GLU C 305 ? THR C 297 GLU C 305 1 ? 9  
HELX_P HELX_P75  AI3 LYS C 307 ? GLN C 316 ? LYS C 307 GLN C 316 1 ? 10 
HELX_P HELX_P76  AI4 SER C 320 ? SER C 327 ? SER C 320 SER C 327 5 ? 8  
HELX_P HELX_P77  AI5 SER C 355 ? HIS C 363 ? SER C 355 HIS C 363 1 ? 9  
HELX_P HELX_P78  AI6 ASN C 368 ? VAL C 373 ? ASN C 368 VAL C 373 1 ? 6  
HELX_P HELX_P79  AI7 PRO C 377 ? TYR C 412 ? PRO C 377 TYR C 412 1 ? 36 
HELX_P HELX_P80  AI8 GLY C 430 ? ARG C 459 ? GLY C 430 ARG C 459 1 ? 30 
HELX_P HELX_P81  AI9 ARG C 460 ? ILE C 463 ? ARG C 460 ILE C 463 5 ? 4  
HELX_P HELX_P82  AJ1 TYR C 471 ? MET C 492 ? TYR C 471 MET C 492 1 ? 22 
HELX_P HELX_P83  AJ2 TRP C 496 ? ASN C 511 ? TRP C 496 ASN C 511 1 ? 16 
HELX_P HELX_P84  AJ3 LEU C 512 ? GLY C 518 ? LEU C 512 GLY C 518 5 ? 7  
HELX_P HELX_P85  AJ4 PHE C 519 ? GLN C 530 ? PHE C 519 GLN C 530 1 ? 12 
HELX_P HELX_P86  AJ5 VAL C 532 ? SER C 559 ? VAL C 532 SER C 559 1 ? 28 
HELX_P HELX_P87  AJ6 SER C 592 ? PHE C 603 ? SER C 592 PHE C 603 1 ? 12 
HELX_P HELX_P88  AJ7 PHE C 618 ? VAL C 649 ? PHE C 618 VAL C 649 1 ? 32 
HELX_P HELX_P89  AJ8 ASN C 655 ? GLU C 672 ? ASN C 655 GLU C 672 1 ? 18 
HELX_P HELX_P90  AJ9 ASN C 711 ? LYS C 717 ? ASN C 711 LYS C 717 1 ? 7  
HELX_P HELX_P91  AK1 ASP D 76  ? GLY D 87  ? ASP D 76  GLY D 87  1 ? 12 
HELX_P HELX_P92  AK2 PRO D 89  ? THR D 93  ? PRO D 89  THR D 93  5 ? 5  
HELX_P HELX_P93  AK3 GLY D 94  ? SER D 103 ? GLY D 94  SER D 103 1 ? 10 
HELX_P HELX_P94  AK4 ASP D 108 ? THR D 112 ? ASP D 108 THR D 112 5 ? 5  
HELX_P HELX_P95  AK5 THR D 119 ? LEU D 126 ? THR D 119 LEU D 126 1 ? 8  
HELX_P HELX_P96  AK6 CYS D 135 ? GLY D 147 ? CYS D 135 GLY D 147 1 ? 13 
HELX_P HELX_P97  AK7 SER D 166 ? LYS D 174 ? SER D 166 LYS D 174 1 ? 9  
HELX_P HELX_P98  AK8 SER D 176 ? ASN D 186 ? SER D 176 ASN D 186 1 ? 11 
HELX_P HELX_P99  AK9 LEU D 212 ? THR D 220 ? LEU D 212 THR D 220 1 ? 9  
HELX_P HELX_P100 AL1 GLN D 222 ? ASN D 232 ? GLN D 222 ASN D 232 1 ? 11 
HELX_P HELX_P101 AL2 THR D 248 ? ALA D 257 ? THR D 248 ALA D 257 1 ? 10 
HELX_P HELX_P102 AL3 SER D 260 ? CYS D 282 ? SER D 260 CYS D 282 1 ? 23 
HELX_P HELX_P103 AL4 GLN D 286 ? ILE D 290 ? GLN D 286 ILE D 290 5 ? 5  
HELX_P HELX_P104 AL5 THR D 297 ? GLU D 305 ? THR D 297 GLU D 305 1 ? 9  
HELX_P HELX_P105 AL6 LYS D 307 ? GLN D 316 ? LYS D 307 GLN D 316 1 ? 10 
HELX_P HELX_P106 AL7 SER D 320 ? SER D 327 ? SER D 320 SER D 327 5 ? 8  
HELX_P HELX_P107 AL8 SER D 355 ? HIS D 363 ? SER D 355 HIS D 363 1 ? 9  
HELX_P HELX_P108 AL9 ASN D 368 ? VAL D 373 ? ASN D 368 VAL D 373 1 ? 6  
HELX_P HELX_P109 AM1 PRO D 377 ? TYR D 412 ? PRO D 377 TYR D 412 1 ? 36 
HELX_P HELX_P110 AM2 GLY D 430 ? ARG D 459 ? GLY D 430 ARG D 459 1 ? 30 
HELX_P HELX_P111 AM3 ARG D 460 ? ILE D 463 ? ARG D 460 ILE D 463 5 ? 4  
HELX_P HELX_P112 AM4 TYR D 471 ? MET D 492 ? TYR D 471 MET D 492 1 ? 22 
HELX_P HELX_P113 AM5 TRP D 496 ? ASN D 511 ? TRP D 496 ASN D 511 1 ? 16 
HELX_P HELX_P114 AM6 LEU D 512 ? GLY D 518 ? LEU D 512 GLY D 518 5 ? 7  
HELX_P HELX_P115 AM7 PHE D 519 ? GLN D 530 ? PHE D 519 GLN D 530 1 ? 12 
HELX_P HELX_P116 AM8 VAL D 532 ? SER D 559 ? VAL D 532 SER D 559 1 ? 28 
HELX_P HELX_P117 AM9 SER D 592 ? PHE D 603 ? SER D 592 PHE D 603 1 ? 12 
HELX_P HELX_P118 AN1 PHE D 618 ? VAL D 649 ? PHE D 618 VAL D 649 1 ? 32 
HELX_P HELX_P119 AN2 ASN D 655 ? GLU D 672 ? ASN D 655 GLU D 672 1 ? 18 
HELX_P HELX_P120 AN3 ASN D 711 ? LYS D 717 ? ASN D 711 LYS D 717 1 ? 7  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 GLU 376 A . ? GLU 376 A PRO 377 A ? PRO 377 A 1 1.17 
2 GLU 376 B . ? GLU 376 B PRO 377 B ? PRO 377 B 1 1.17 
3 GLU 376 C . ? GLU 376 C PRO 377 C ? PRO 377 C 1 1.17 
4 GLU 376 D . ? GLU 376 D PRO 377 D ? PRO 377 D 1 1.17 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 2 ? 
AA3 ? 4 ? 
AA4 ? 2 ? 
AA5 ? 4 ? 
AA6 ? 2 ? 
AA7 ? 4 ? 
AA8 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LYS A 329 ? TYR A 335 ? LYS A 329 TYR A 335 
AA1 2 VAL A 338 ? ASP A 344 ? VAL A 338 ASP A 344 
AA1 3 ASP A 700 ? VAL A 710 ? ASP A 700 VAL A 710 
AA1 4 ARG A 687 ? GLY A 692 ? ARG A 687 GLY A 692 
AA2 1 GLY A 674 ? TYR A 675 ? GLY A 674 TYR A 675 
AA2 2 CYS A 678 ? ARG A 679 ? CYS A 678 ARG A 679 
AA3 1 LYS B 329 ? TYR B 335 ? LYS B 329 TYR B 335 
AA3 2 VAL B 338 ? ASP B 344 ? VAL B 338 ASP B 344 
AA3 3 ASP B 700 ? VAL B 710 ? ASP B 700 VAL B 710 
AA3 4 ARG B 687 ? GLY B 692 ? ARG B 687 GLY B 692 
AA4 1 GLY B 674 ? TYR B 675 ? GLY B 674 TYR B 675 
AA4 2 CYS B 678 ? ARG B 679 ? CYS B 678 ARG B 679 
AA5 1 LYS C 329 ? TYR C 335 ? LYS C 329 TYR C 335 
AA5 2 VAL C 338 ? ASP C 344 ? VAL C 338 ASP C 344 
AA5 3 ASP C 700 ? VAL C 710 ? ASP C 700 VAL C 710 
AA5 4 ARG C 687 ? GLY C 692 ? ARG C 687 GLY C 692 
AA6 1 GLY C 674 ? TYR C 675 ? GLY C 674 TYR C 675 
AA6 2 CYS C 678 ? ARG C 679 ? CYS C 678 ARG C 679 
AA7 1 LYS D 329 ? TYR D 335 ? LYS D 329 TYR D 335 
AA7 2 VAL D 338 ? ASP D 344 ? VAL D 338 ASP D 344 
AA7 3 ASP D 700 ? VAL D 710 ? ASP D 700 VAL D 710 
AA7 4 ARG D 687 ? GLY D 692 ? ARG D 687 GLY D 692 
AA8 1 GLY D 674 ? TYR D 675 ? GLY D 674 TYR D 675 
AA8 2 CYS D 678 ? ARG D 679 ? CYS D 678 ARG D 679 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N TRP A 333 ? N TRP A 333 O VAL A 340 ? O VAL A 340 
AA1 2 3 N ARG A 339 ? N ARG A 339 O GLU A 709 ? O GLU A 709 
AA1 3 4 O CYS A 704 ? O CYS A 704 N ARG A 687 ? N ARG A 687 
AA2 1 2 N TYR A 675 ? N TYR A 675 O CYS A 678 ? O CYS A 678 
AA3 1 2 N TRP B 333 ? N TRP B 333 O VAL B 340 ? O VAL B 340 
AA3 2 3 N ARG B 339 ? N ARG B 339 O GLU B 709 ? O GLU B 709 
AA3 3 4 O CYS B 704 ? O CYS B 704 N ARG B 687 ? N ARG B 687 
AA4 1 2 N TYR B 675 ? N TYR B 675 O CYS B 678 ? O CYS B 678 
AA5 1 2 N TRP C 333 ? N TRP C 333 O VAL C 340 ? O VAL C 340 
AA5 2 3 N ARG C 339 ? N ARG C 339 O GLU C 709 ? O GLU C 709 
AA5 3 4 O CYS C 704 ? O CYS C 704 N ARG C 687 ? N ARG C 687 
AA6 1 2 N TYR C 675 ? N TYR C 675 O CYS C 678 ? O CYS C 678 
AA7 1 2 N TRP D 333 ? N TRP D 333 O VAL D 340 ? O VAL D 340 
AA7 2 3 N ARG D 339 ? N ARG D 339 O GLU D 709 ? O GLU D 709 
AA7 3 4 O CYS D 704 ? O CYS D 704 N ARG D 687 ? N ARG D 687 
AA8 1 2 N TYR D 675 ? N TYR D 675 O CYS D 678 ? O CYS D 678 
# 
_pdbx_entry_details.entry_id                   9B3Y 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 GLN A 235 ? ? -160.05 95.49   
2  1 SER A 470 ? ? -90.69  54.13   
3  1 GLU A 493 ? ? 58.37   15.65   
4  1 LYS A 531 ? ? -160.12 -164.77 
5  1 VAL A 532 ? ? -46.81  -19.75  
6  1 PHE A 618 ? ? -97.18  32.13   
7  1 VAL A 649 ? ? -100.65 72.44   
8  1 HIS A 651 ? ? 83.49   -5.91   
9  1 TRP A 703 ? ? -69.30  93.07   
10 1 GLN B 235 ? ? -160.05 95.49   
11 1 SER B 470 ? ? -90.69  54.13   
12 1 GLU B 493 ? ? 58.37   15.65   
13 1 LYS B 531 ? ? -160.12 -164.77 
14 1 VAL B 532 ? ? -46.81  -19.75  
15 1 PHE B 618 ? ? -97.18  32.13   
16 1 VAL B 649 ? ? -100.63 72.44   
17 1 HIS B 651 ? ? 83.54   -5.91   
18 1 TRP B 703 ? ? -69.30  93.07   
19 1 GLN C 235 ? ? -160.05 95.49   
20 1 SER C 470 ? ? -90.69  54.13   
21 1 GLU C 493 ? ? 58.37   15.65   
22 1 LYS C 531 ? ? -160.12 -164.77 
23 1 VAL C 532 ? ? -46.81  -19.75  
24 1 PHE C 618 ? ? -97.18  32.13   
25 1 VAL C 649 ? ? -100.65 72.44   
26 1 HIS C 651 ? ? 83.51   -5.88   
27 1 TRP C 703 ? ? -69.30  93.07   
28 1 GLN D 235 ? ? -160.05 95.49   
29 1 SER D 470 ? ? -90.69  54.13   
30 1 GLU D 493 ? ? 58.37   15.65   
31 1 LYS D 531 ? ? -160.12 -164.77 
32 1 VAL D 532 ? ? -46.81  -19.75  
33 1 PHE D 618 ? ? -97.18  32.13   
34 1 VAL D 649 ? ? -100.63 72.40   
35 1 HIS D 651 ? ? 83.54   -5.91   
36 1 TRP D 703 ? ? -69.30  93.07   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9B3Y 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9B3Y 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.7 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               231568 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Homotetramer of rat TRPV2 E724A/D725A mutant' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9B3Y 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             500 
_em_imaging.nominal_defocus_max             2500 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9B3Y 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9B3Y 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              9B3Y 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        C4 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A THR 2   ? A THR 2   
3   1 Y 1 A SER 3   ? A SER 3   
4   1 Y 1 A ALA 4   ? A ALA 4   
5   1 Y 1 A SER 5   ? A SER 5   
6   1 Y 1 A SER 6   ? A SER 6   
7   1 Y 1 A PRO 7   ? A PRO 7   
8   1 Y 1 A PRO 8   ? A PRO 8   
9   1 Y 1 A ALA 9   ? A ALA 9   
10  1 Y 1 A PHE 10  ? A PHE 10  
11  1 Y 1 A ARG 11  ? A ARG 11  
12  1 Y 1 A LEU 12  ? A LEU 12  
13  1 Y 1 A GLU 13  ? A GLU 13  
14  1 Y 1 A THR 14  ? A THR 14  
15  1 Y 1 A SER 15  ? A SER 15  
16  1 Y 1 A ASP 16  ? A ASP 16  
17  1 Y 1 A GLY 17  ? A GLY 17  
18  1 Y 1 A ASP 18  ? A ASP 18  
19  1 Y 1 A GLU 19  ? A GLU 19  
20  1 Y 1 A GLU 20  ? A GLU 20  
21  1 Y 1 A GLY 21  ? A GLY 21  
22  1 Y 1 A ASN 22  ? A ASN 22  
23  1 Y 1 A ALA 23  ? A ALA 23  
24  1 Y 1 A GLU 24  ? A GLU 24  
25  1 Y 1 A VAL 25  ? A VAL 25  
26  1 Y 1 A ASN 26  ? A ASN 26  
27  1 Y 1 A LYS 27  ? A LYS 27  
28  1 Y 1 A GLY 28  ? A GLY 28  
29  1 Y 1 A LYS 29  ? A LYS 29  
30  1 Y 1 A GLN 30  ? A GLN 30  
31  1 Y 1 A GLU 31  ? A GLU 31  
32  1 Y 1 A PRO 32  ? A PRO 32  
33  1 Y 1 A PRO 33  ? A PRO 33  
34  1 Y 1 A PRO 34  ? A PRO 34  
35  1 Y 1 A MET 35  ? A MET 35  
36  1 Y 1 A GLU 36  ? A GLU 36  
37  1 Y 1 A SER 37  ? A SER 37  
38  1 Y 1 A PRO 38  ? A PRO 38  
39  1 Y 1 A PHE 39  ? A PHE 39  
40  1 Y 1 A GLN 40  ? A GLN 40  
41  1 Y 1 A ARG 41  ? A ARG 41  
42  1 Y 1 A GLU 42  ? A GLU 42  
43  1 Y 1 A ASP 43  ? A ASP 43  
44  1 Y 1 A ARG 44  ? A ARG 44  
45  1 Y 1 A ASN 45  ? A ASN 45  
46  1 Y 1 A SER 46  ? A SER 46  
47  1 Y 1 A SER 47  ? A SER 47  
48  1 Y 1 A PRO 48  ? A PRO 48  
49  1 Y 1 A GLN 49  ? A GLN 49  
50  1 Y 1 A ILE 50  ? A ILE 50  
51  1 Y 1 A LYS 51  ? A LYS 51  
52  1 Y 1 A VAL 52  ? A VAL 52  
53  1 Y 1 A ASN 53  ? A ASN 53  
54  1 Y 1 A LEU 54  ? A LEU 54  
55  1 Y 1 A ASN 55  ? A ASN 55  
56  1 Y 1 A PHE 56  ? A PHE 56  
57  1 Y 1 A ILE 57  ? A ILE 57  
58  1 Y 1 A LYS 58  ? A LYS 58  
59  1 Y 1 A ARG 59  ? A ARG 59  
60  1 Y 1 A PRO 60  ? A PRO 60  
61  1 Y 1 A PRO 61  ? A PRO 61  
62  1 Y 1 A LYS 62  ? A LYS 62  
63  1 Y 1 A ASN 63  ? A ASN 63  
64  1 Y 1 A THR 64  ? A THR 64  
65  1 Y 1 A SER 65  ? A SER 65  
66  1 Y 1 A ALA 66  ? A ALA 66  
67  1 Y 1 A PRO 67  ? A PRO 67  
68  1 Y 1 A SER 68  ? A SER 68  
69  1 Y 1 A GLN 69  ? A GLN 69  
70  1 Y 1 A GLN 70  ? A GLN 70  
71  1 Y 1 A GLU 71  ? A GLU 71  
72  1 Y 1 A PRO 72  ? A PRO 72  
73  1 Y 1 A ASP 73  ? A ASP 73  
74  1 Y 1 A ASP 418 ? A ASP 418 
75  1 Y 1 A GLN 419 ? A GLN 419 
76  1 Y 1 A PRO 420 ? A PRO 420 
77  1 Y 1 A ALA 421 ? A ALA 421 
78  1 Y 1 A ILE 422 ? A ILE 422 
79  1 Y 1 A PRO 423 ? A PRO 423 
80  1 Y 1 A SER 424 ? A SER 424 
81  1 Y 1 A SER 425 ? A SER 425 
82  1 Y 1 A LYS 426 ? A LYS 426 
83  1 Y 1 A ALA 427 ? A ALA 427 
84  1 Y 1 A THR 428 ? A THR 428 
85  1 Y 1 A SER 564 ? A SER 564 
86  1 Y 1 A PRO 565 ? A PRO 565 
87  1 Y 1 A LYS 566 ? A LYS 566 
88  1 Y 1 A ALA 567 ? A ALA 567 
89  1 Y 1 A PRO 568 ? A PRO 568 
90  1 Y 1 A GLU 569 ? A GLU 569 
91  1 Y 1 A ASP 570 ? A ASP 570 
92  1 Y 1 A ASN 571 ? A ASN 571 
93  1 Y 1 A ASN 572 ? A ASN 572 
94  1 Y 1 A SER 573 ? A SER 573 
95  1 Y 1 A THR 574 ? A THR 574 
96  1 Y 1 A VAL 575 ? A VAL 575 
97  1 Y 1 A THR 576 ? A THR 576 
98  1 Y 1 A GLU 577 ? A GLU 577 
99  1 Y 1 A GLN 578 ? A GLN 578 
100 1 Y 1 A PRO 579 ? A PRO 579 
101 1 Y 1 A THR 580 ? A THR 580 
102 1 Y 1 A VAL 581 ? A VAL 581 
103 1 Y 1 A GLY 582 ? A GLY 582 
104 1 Y 1 A GLN 583 ? A GLN 583 
105 1 Y 1 A GLU 584 ? A GLU 584 
106 1 Y 1 A GLU 585 ? A GLU 585 
107 1 Y 1 A GLU 586 ? A GLU 586 
108 1 Y 1 A PRO 587 ? A PRO 587 
109 1 Y 1 A ALA 588 ? A ALA 588 
110 1 Y 1 A GLY 695 ? A GLY 695 
111 1 Y 1 A ASP 696 ? A ASP 696 
112 1 Y 1 A GLY 697 ? A GLY 697 
113 1 Y 1 A THR 698 ? A THR 698 
114 1 Y 1 A PRO 720 ? A PRO 720 
115 1 Y 1 A THR 721 ? A THR 721 
116 1 Y 1 A LEU 722 ? A LEU 722 
117 1 Y 1 A SER 723 ? A SER 723 
118 1 Y 1 A ALA 724 ? A ALA 724 
119 1 Y 1 A ALA 725 ? A ALA 725 
120 1 Y 1 A PRO 726 ? A PRO 726 
121 1 Y 1 A SER 727 ? A SER 727 
122 1 Y 1 A GLY 728 ? A GLY 728 
123 1 Y 1 A PRO 729 ? A PRO 729 
124 1 Y 1 A GLY 730 ? A GLY 730 
125 1 Y 1 A ILE 731 ? A ILE 731 
126 1 Y 1 A THR 732 ? A THR 732 
127 1 Y 1 A GLY 733 ? A GLY 733 
128 1 Y 1 A ASN 734 ? A ASN 734 
129 1 Y 1 A LYS 735 ? A LYS 735 
130 1 Y 1 A LYS 736 ? A LYS 736 
131 1 Y 1 A ASN 737 ? A ASN 737 
132 1 Y 1 A PRO 738 ? A PRO 738 
133 1 Y 1 A THR 739 ? A THR 739 
134 1 Y 1 A SER 740 ? A SER 740 
135 1 Y 1 A LYS 741 ? A LYS 741 
136 1 Y 1 A PRO 742 ? A PRO 742 
137 1 Y 1 A GLY 743 ? A GLY 743 
138 1 Y 1 A LYS 744 ? A LYS 744 
139 1 Y 1 A ASN 745 ? A ASN 745 
140 1 Y 1 A SER 746 ? A SER 746 
141 1 Y 1 A ALA 747 ? A ALA 747 
142 1 Y 1 A SER 748 ? A SER 748 
143 1 Y 1 A GLU 749 ? A GLU 749 
144 1 Y 1 A GLU 750 ? A GLU 750 
145 1 Y 1 A ASP 751 ? A ASP 751 
146 1 Y 1 A HIS 752 ? A HIS 752 
147 1 Y 1 A LEU 753 ? A LEU 753 
148 1 Y 1 A PRO 754 ? A PRO 754 
149 1 Y 1 A LEU 755 ? A LEU 755 
150 1 Y 1 A GLN 756 ? A GLN 756 
151 1 Y 1 A VAL 757 ? A VAL 757 
152 1 Y 1 A LEU 758 ? A LEU 758 
153 1 Y 1 A GLN 759 ? A GLN 759 
154 1 Y 1 A SER 760 ? A SER 760 
155 1 Y 1 A PRO 761 ? A PRO 761 
156 1 Y 1 B MET 1   ? B MET 1   
157 1 Y 1 B THR 2   ? B THR 2   
158 1 Y 1 B SER 3   ? B SER 3   
159 1 Y 1 B ALA 4   ? B ALA 4   
160 1 Y 1 B SER 5   ? B SER 5   
161 1 Y 1 B SER 6   ? B SER 6   
162 1 Y 1 B PRO 7   ? B PRO 7   
163 1 Y 1 B PRO 8   ? B PRO 8   
164 1 Y 1 B ALA 9   ? B ALA 9   
165 1 Y 1 B PHE 10  ? B PHE 10  
166 1 Y 1 B ARG 11  ? B ARG 11  
167 1 Y 1 B LEU 12  ? B LEU 12  
168 1 Y 1 B GLU 13  ? B GLU 13  
169 1 Y 1 B THR 14  ? B THR 14  
170 1 Y 1 B SER 15  ? B SER 15  
171 1 Y 1 B ASP 16  ? B ASP 16  
172 1 Y 1 B GLY 17  ? B GLY 17  
173 1 Y 1 B ASP 18  ? B ASP 18  
174 1 Y 1 B GLU 19  ? B GLU 19  
175 1 Y 1 B GLU 20  ? B GLU 20  
176 1 Y 1 B GLY 21  ? B GLY 21  
177 1 Y 1 B ASN 22  ? B ASN 22  
178 1 Y 1 B ALA 23  ? B ALA 23  
179 1 Y 1 B GLU 24  ? B GLU 24  
180 1 Y 1 B VAL 25  ? B VAL 25  
181 1 Y 1 B ASN 26  ? B ASN 26  
182 1 Y 1 B LYS 27  ? B LYS 27  
183 1 Y 1 B GLY 28  ? B GLY 28  
184 1 Y 1 B LYS 29  ? B LYS 29  
185 1 Y 1 B GLN 30  ? B GLN 30  
186 1 Y 1 B GLU 31  ? B GLU 31  
187 1 Y 1 B PRO 32  ? B PRO 32  
188 1 Y 1 B PRO 33  ? B PRO 33  
189 1 Y 1 B PRO 34  ? B PRO 34  
190 1 Y 1 B MET 35  ? B MET 35  
191 1 Y 1 B GLU 36  ? B GLU 36  
192 1 Y 1 B SER 37  ? B SER 37  
193 1 Y 1 B PRO 38  ? B PRO 38  
194 1 Y 1 B PHE 39  ? B PHE 39  
195 1 Y 1 B GLN 40  ? B GLN 40  
196 1 Y 1 B ARG 41  ? B ARG 41  
197 1 Y 1 B GLU 42  ? B GLU 42  
198 1 Y 1 B ASP 43  ? B ASP 43  
199 1 Y 1 B ARG 44  ? B ARG 44  
200 1 Y 1 B ASN 45  ? B ASN 45  
201 1 Y 1 B SER 46  ? B SER 46  
202 1 Y 1 B SER 47  ? B SER 47  
203 1 Y 1 B PRO 48  ? B PRO 48  
204 1 Y 1 B GLN 49  ? B GLN 49  
205 1 Y 1 B ILE 50  ? B ILE 50  
206 1 Y 1 B LYS 51  ? B LYS 51  
207 1 Y 1 B VAL 52  ? B VAL 52  
208 1 Y 1 B ASN 53  ? B ASN 53  
209 1 Y 1 B LEU 54  ? B LEU 54  
210 1 Y 1 B ASN 55  ? B ASN 55  
211 1 Y 1 B PHE 56  ? B PHE 56  
212 1 Y 1 B ILE 57  ? B ILE 57  
213 1 Y 1 B LYS 58  ? B LYS 58  
214 1 Y 1 B ARG 59  ? B ARG 59  
215 1 Y 1 B PRO 60  ? B PRO 60  
216 1 Y 1 B PRO 61  ? B PRO 61  
217 1 Y 1 B LYS 62  ? B LYS 62  
218 1 Y 1 B ASN 63  ? B ASN 63  
219 1 Y 1 B THR 64  ? B THR 64  
220 1 Y 1 B SER 65  ? B SER 65  
221 1 Y 1 B ALA 66  ? B ALA 66  
222 1 Y 1 B PRO 67  ? B PRO 67  
223 1 Y 1 B SER 68  ? B SER 68  
224 1 Y 1 B GLN 69  ? B GLN 69  
225 1 Y 1 B GLN 70  ? B GLN 70  
226 1 Y 1 B GLU 71  ? B GLU 71  
227 1 Y 1 B PRO 72  ? B PRO 72  
228 1 Y 1 B ASP 73  ? B ASP 73  
229 1 Y 1 B ASP 418 ? B ASP 418 
230 1 Y 1 B GLN 419 ? B GLN 419 
231 1 Y 1 B PRO 420 ? B PRO 420 
232 1 Y 1 B ALA 421 ? B ALA 421 
233 1 Y 1 B ILE 422 ? B ILE 422 
234 1 Y 1 B PRO 423 ? B PRO 423 
235 1 Y 1 B SER 424 ? B SER 424 
236 1 Y 1 B SER 425 ? B SER 425 
237 1 Y 1 B LYS 426 ? B LYS 426 
238 1 Y 1 B ALA 427 ? B ALA 427 
239 1 Y 1 B THR 428 ? B THR 428 
240 1 Y 1 B SER 564 ? B SER 564 
241 1 Y 1 B PRO 565 ? B PRO 565 
242 1 Y 1 B LYS 566 ? B LYS 566 
243 1 Y 1 B ALA 567 ? B ALA 567 
244 1 Y 1 B PRO 568 ? B PRO 568 
245 1 Y 1 B GLU 569 ? B GLU 569 
246 1 Y 1 B ASP 570 ? B ASP 570 
247 1 Y 1 B ASN 571 ? B ASN 571 
248 1 Y 1 B ASN 572 ? B ASN 572 
249 1 Y 1 B SER 573 ? B SER 573 
250 1 Y 1 B THR 574 ? B THR 574 
251 1 Y 1 B VAL 575 ? B VAL 575 
252 1 Y 1 B THR 576 ? B THR 576 
253 1 Y 1 B GLU 577 ? B GLU 577 
254 1 Y 1 B GLN 578 ? B GLN 578 
255 1 Y 1 B PRO 579 ? B PRO 579 
256 1 Y 1 B THR 580 ? B THR 580 
257 1 Y 1 B VAL 581 ? B VAL 581 
258 1 Y 1 B GLY 582 ? B GLY 582 
259 1 Y 1 B GLN 583 ? B GLN 583 
260 1 Y 1 B GLU 584 ? B GLU 584 
261 1 Y 1 B GLU 585 ? B GLU 585 
262 1 Y 1 B GLU 586 ? B GLU 586 
263 1 Y 1 B PRO 587 ? B PRO 587 
264 1 Y 1 B ALA 588 ? B ALA 588 
265 1 Y 1 B GLY 695 ? B GLY 695 
266 1 Y 1 B ASP 696 ? B ASP 696 
267 1 Y 1 B GLY 697 ? B GLY 697 
268 1 Y 1 B THR 698 ? B THR 698 
269 1 Y 1 B PRO 720 ? B PRO 720 
270 1 Y 1 B THR 721 ? B THR 721 
271 1 Y 1 B LEU 722 ? B LEU 722 
272 1 Y 1 B SER 723 ? B SER 723 
273 1 Y 1 B ALA 724 ? B ALA 724 
274 1 Y 1 B ALA 725 ? B ALA 725 
275 1 Y 1 B PRO 726 ? B PRO 726 
276 1 Y 1 B SER 727 ? B SER 727 
277 1 Y 1 B GLY 728 ? B GLY 728 
278 1 Y 1 B PRO 729 ? B PRO 729 
279 1 Y 1 B GLY 730 ? B GLY 730 
280 1 Y 1 B ILE 731 ? B ILE 731 
281 1 Y 1 B THR 732 ? B THR 732 
282 1 Y 1 B GLY 733 ? B GLY 733 
283 1 Y 1 B ASN 734 ? B ASN 734 
284 1 Y 1 B LYS 735 ? B LYS 735 
285 1 Y 1 B LYS 736 ? B LYS 736 
286 1 Y 1 B ASN 737 ? B ASN 737 
287 1 Y 1 B PRO 738 ? B PRO 738 
288 1 Y 1 B THR 739 ? B THR 739 
289 1 Y 1 B SER 740 ? B SER 740 
290 1 Y 1 B LYS 741 ? B LYS 741 
291 1 Y 1 B PRO 742 ? B PRO 742 
292 1 Y 1 B GLY 743 ? B GLY 743 
293 1 Y 1 B LYS 744 ? B LYS 744 
294 1 Y 1 B ASN 745 ? B ASN 745 
295 1 Y 1 B SER 746 ? B SER 746 
296 1 Y 1 B ALA 747 ? B ALA 747 
297 1 Y 1 B SER 748 ? B SER 748 
298 1 Y 1 B GLU 749 ? B GLU 749 
299 1 Y 1 B GLU 750 ? B GLU 750 
300 1 Y 1 B ASP 751 ? B ASP 751 
301 1 Y 1 B HIS 752 ? B HIS 752 
302 1 Y 1 B LEU 753 ? B LEU 753 
303 1 Y 1 B PRO 754 ? B PRO 754 
304 1 Y 1 B LEU 755 ? B LEU 755 
305 1 Y 1 B GLN 756 ? B GLN 756 
306 1 Y 1 B VAL 757 ? B VAL 757 
307 1 Y 1 B LEU 758 ? B LEU 758 
308 1 Y 1 B GLN 759 ? B GLN 759 
309 1 Y 1 B SER 760 ? B SER 760 
310 1 Y 1 B PRO 761 ? B PRO 761 
311 1 Y 1 C MET 1   ? C MET 1   
312 1 Y 1 C THR 2   ? C THR 2   
313 1 Y 1 C SER 3   ? C SER 3   
314 1 Y 1 C ALA 4   ? C ALA 4   
315 1 Y 1 C SER 5   ? C SER 5   
316 1 Y 1 C SER 6   ? C SER 6   
317 1 Y 1 C PRO 7   ? C PRO 7   
318 1 Y 1 C PRO 8   ? C PRO 8   
319 1 Y 1 C ALA 9   ? C ALA 9   
320 1 Y 1 C PHE 10  ? C PHE 10  
321 1 Y 1 C ARG 11  ? C ARG 11  
322 1 Y 1 C LEU 12  ? C LEU 12  
323 1 Y 1 C GLU 13  ? C GLU 13  
324 1 Y 1 C THR 14  ? C THR 14  
325 1 Y 1 C SER 15  ? C SER 15  
326 1 Y 1 C ASP 16  ? C ASP 16  
327 1 Y 1 C GLY 17  ? C GLY 17  
328 1 Y 1 C ASP 18  ? C ASP 18  
329 1 Y 1 C GLU 19  ? C GLU 19  
330 1 Y 1 C GLU 20  ? C GLU 20  
331 1 Y 1 C GLY 21  ? C GLY 21  
332 1 Y 1 C ASN 22  ? C ASN 22  
333 1 Y 1 C ALA 23  ? C ALA 23  
334 1 Y 1 C GLU 24  ? C GLU 24  
335 1 Y 1 C VAL 25  ? C VAL 25  
336 1 Y 1 C ASN 26  ? C ASN 26  
337 1 Y 1 C LYS 27  ? C LYS 27  
338 1 Y 1 C GLY 28  ? C GLY 28  
339 1 Y 1 C LYS 29  ? C LYS 29  
340 1 Y 1 C GLN 30  ? C GLN 30  
341 1 Y 1 C GLU 31  ? C GLU 31  
342 1 Y 1 C PRO 32  ? C PRO 32  
343 1 Y 1 C PRO 33  ? C PRO 33  
344 1 Y 1 C PRO 34  ? C PRO 34  
345 1 Y 1 C MET 35  ? C MET 35  
346 1 Y 1 C GLU 36  ? C GLU 36  
347 1 Y 1 C SER 37  ? C SER 37  
348 1 Y 1 C PRO 38  ? C PRO 38  
349 1 Y 1 C PHE 39  ? C PHE 39  
350 1 Y 1 C GLN 40  ? C GLN 40  
351 1 Y 1 C ARG 41  ? C ARG 41  
352 1 Y 1 C GLU 42  ? C GLU 42  
353 1 Y 1 C ASP 43  ? C ASP 43  
354 1 Y 1 C ARG 44  ? C ARG 44  
355 1 Y 1 C ASN 45  ? C ASN 45  
356 1 Y 1 C SER 46  ? C SER 46  
357 1 Y 1 C SER 47  ? C SER 47  
358 1 Y 1 C PRO 48  ? C PRO 48  
359 1 Y 1 C GLN 49  ? C GLN 49  
360 1 Y 1 C ILE 50  ? C ILE 50  
361 1 Y 1 C LYS 51  ? C LYS 51  
362 1 Y 1 C VAL 52  ? C VAL 52  
363 1 Y 1 C ASN 53  ? C ASN 53  
364 1 Y 1 C LEU 54  ? C LEU 54  
365 1 Y 1 C ASN 55  ? C ASN 55  
366 1 Y 1 C PHE 56  ? C PHE 56  
367 1 Y 1 C ILE 57  ? C ILE 57  
368 1 Y 1 C LYS 58  ? C LYS 58  
369 1 Y 1 C ARG 59  ? C ARG 59  
370 1 Y 1 C PRO 60  ? C PRO 60  
371 1 Y 1 C PRO 61  ? C PRO 61  
372 1 Y 1 C LYS 62  ? C LYS 62  
373 1 Y 1 C ASN 63  ? C ASN 63  
374 1 Y 1 C THR 64  ? C THR 64  
375 1 Y 1 C SER 65  ? C SER 65  
376 1 Y 1 C ALA 66  ? C ALA 66  
377 1 Y 1 C PRO 67  ? C PRO 67  
378 1 Y 1 C SER 68  ? C SER 68  
379 1 Y 1 C GLN 69  ? C GLN 69  
380 1 Y 1 C GLN 70  ? C GLN 70  
381 1 Y 1 C GLU 71  ? C GLU 71  
382 1 Y 1 C PRO 72  ? C PRO 72  
383 1 Y 1 C ASP 73  ? C ASP 73  
384 1 Y 1 C ASP 418 ? C ASP 418 
385 1 Y 1 C GLN 419 ? C GLN 419 
386 1 Y 1 C PRO 420 ? C PRO 420 
387 1 Y 1 C ALA 421 ? C ALA 421 
388 1 Y 1 C ILE 422 ? C ILE 422 
389 1 Y 1 C PRO 423 ? C PRO 423 
390 1 Y 1 C SER 424 ? C SER 424 
391 1 Y 1 C SER 425 ? C SER 425 
392 1 Y 1 C LYS 426 ? C LYS 426 
393 1 Y 1 C ALA 427 ? C ALA 427 
394 1 Y 1 C THR 428 ? C THR 428 
395 1 Y 1 C SER 564 ? C SER 564 
396 1 Y 1 C PRO 565 ? C PRO 565 
397 1 Y 1 C LYS 566 ? C LYS 566 
398 1 Y 1 C ALA 567 ? C ALA 567 
399 1 Y 1 C PRO 568 ? C PRO 568 
400 1 Y 1 C GLU 569 ? C GLU 569 
401 1 Y 1 C ASP 570 ? C ASP 570 
402 1 Y 1 C ASN 571 ? C ASN 571 
403 1 Y 1 C ASN 572 ? C ASN 572 
404 1 Y 1 C SER 573 ? C SER 573 
405 1 Y 1 C THR 574 ? C THR 574 
406 1 Y 1 C VAL 575 ? C VAL 575 
407 1 Y 1 C THR 576 ? C THR 576 
408 1 Y 1 C GLU 577 ? C GLU 577 
409 1 Y 1 C GLN 578 ? C GLN 578 
410 1 Y 1 C PRO 579 ? C PRO 579 
411 1 Y 1 C THR 580 ? C THR 580 
412 1 Y 1 C VAL 581 ? C VAL 581 
413 1 Y 1 C GLY 582 ? C GLY 582 
414 1 Y 1 C GLN 583 ? C GLN 583 
415 1 Y 1 C GLU 584 ? C GLU 584 
416 1 Y 1 C GLU 585 ? C GLU 585 
417 1 Y 1 C GLU 586 ? C GLU 586 
418 1 Y 1 C PRO 587 ? C PRO 587 
419 1 Y 1 C ALA 588 ? C ALA 588 
420 1 Y 1 C GLY 695 ? C GLY 695 
421 1 Y 1 C ASP 696 ? C ASP 696 
422 1 Y 1 C GLY 697 ? C GLY 697 
423 1 Y 1 C THR 698 ? C THR 698 
424 1 Y 1 C PRO 720 ? C PRO 720 
425 1 Y 1 C THR 721 ? C THR 721 
426 1 Y 1 C LEU 722 ? C LEU 722 
427 1 Y 1 C SER 723 ? C SER 723 
428 1 Y 1 C ALA 724 ? C ALA 724 
429 1 Y 1 C ALA 725 ? C ALA 725 
430 1 Y 1 C PRO 726 ? C PRO 726 
431 1 Y 1 C SER 727 ? C SER 727 
432 1 Y 1 C GLY 728 ? C GLY 728 
433 1 Y 1 C PRO 729 ? C PRO 729 
434 1 Y 1 C GLY 730 ? C GLY 730 
435 1 Y 1 C ILE 731 ? C ILE 731 
436 1 Y 1 C THR 732 ? C THR 732 
437 1 Y 1 C GLY 733 ? C GLY 733 
438 1 Y 1 C ASN 734 ? C ASN 734 
439 1 Y 1 C LYS 735 ? C LYS 735 
440 1 Y 1 C LYS 736 ? C LYS 736 
441 1 Y 1 C ASN 737 ? C ASN 737 
442 1 Y 1 C PRO 738 ? C PRO 738 
443 1 Y 1 C THR 739 ? C THR 739 
444 1 Y 1 C SER 740 ? C SER 740 
445 1 Y 1 C LYS 741 ? C LYS 741 
446 1 Y 1 C PRO 742 ? C PRO 742 
447 1 Y 1 C GLY 743 ? C GLY 743 
448 1 Y 1 C LYS 744 ? C LYS 744 
449 1 Y 1 C ASN 745 ? C ASN 745 
450 1 Y 1 C SER 746 ? C SER 746 
451 1 Y 1 C ALA 747 ? C ALA 747 
452 1 Y 1 C SER 748 ? C SER 748 
453 1 Y 1 C GLU 749 ? C GLU 749 
454 1 Y 1 C GLU 750 ? C GLU 750 
455 1 Y 1 C ASP 751 ? C ASP 751 
456 1 Y 1 C HIS 752 ? C HIS 752 
457 1 Y 1 C LEU 753 ? C LEU 753 
458 1 Y 1 C PRO 754 ? C PRO 754 
459 1 Y 1 C LEU 755 ? C LEU 755 
460 1 Y 1 C GLN 756 ? C GLN 756 
461 1 Y 1 C VAL 757 ? C VAL 757 
462 1 Y 1 C LEU 758 ? C LEU 758 
463 1 Y 1 C GLN 759 ? C GLN 759 
464 1 Y 1 C SER 760 ? C SER 760 
465 1 Y 1 C PRO 761 ? C PRO 761 
466 1 Y 1 D MET 1   ? D MET 1   
467 1 Y 1 D THR 2   ? D THR 2   
468 1 Y 1 D SER 3   ? D SER 3   
469 1 Y 1 D ALA 4   ? D ALA 4   
470 1 Y 1 D SER 5   ? D SER 5   
471 1 Y 1 D SER 6   ? D SER 6   
472 1 Y 1 D PRO 7   ? D PRO 7   
473 1 Y 1 D PRO 8   ? D PRO 8   
474 1 Y 1 D ALA 9   ? D ALA 9   
475 1 Y 1 D PHE 10  ? D PHE 10  
476 1 Y 1 D ARG 11  ? D ARG 11  
477 1 Y 1 D LEU 12  ? D LEU 12  
478 1 Y 1 D GLU 13  ? D GLU 13  
479 1 Y 1 D THR 14  ? D THR 14  
480 1 Y 1 D SER 15  ? D SER 15  
481 1 Y 1 D ASP 16  ? D ASP 16  
482 1 Y 1 D GLY 17  ? D GLY 17  
483 1 Y 1 D ASP 18  ? D ASP 18  
484 1 Y 1 D GLU 19  ? D GLU 19  
485 1 Y 1 D GLU 20  ? D GLU 20  
486 1 Y 1 D GLY 21  ? D GLY 21  
487 1 Y 1 D ASN 22  ? D ASN 22  
488 1 Y 1 D ALA 23  ? D ALA 23  
489 1 Y 1 D GLU 24  ? D GLU 24  
490 1 Y 1 D VAL 25  ? D VAL 25  
491 1 Y 1 D ASN 26  ? D ASN 26  
492 1 Y 1 D LYS 27  ? D LYS 27  
493 1 Y 1 D GLY 28  ? D GLY 28  
494 1 Y 1 D LYS 29  ? D LYS 29  
495 1 Y 1 D GLN 30  ? D GLN 30  
496 1 Y 1 D GLU 31  ? D GLU 31  
497 1 Y 1 D PRO 32  ? D PRO 32  
498 1 Y 1 D PRO 33  ? D PRO 33  
499 1 Y 1 D PRO 34  ? D PRO 34  
500 1 Y 1 D MET 35  ? D MET 35  
501 1 Y 1 D GLU 36  ? D GLU 36  
502 1 Y 1 D SER 37  ? D SER 37  
503 1 Y 1 D PRO 38  ? D PRO 38  
504 1 Y 1 D PHE 39  ? D PHE 39  
505 1 Y 1 D GLN 40  ? D GLN 40  
506 1 Y 1 D ARG 41  ? D ARG 41  
507 1 Y 1 D GLU 42  ? D GLU 42  
508 1 Y 1 D ASP 43  ? D ASP 43  
509 1 Y 1 D ARG 44  ? D ARG 44  
510 1 Y 1 D ASN 45  ? D ASN 45  
511 1 Y 1 D SER 46  ? D SER 46  
512 1 Y 1 D SER 47  ? D SER 47  
513 1 Y 1 D PRO 48  ? D PRO 48  
514 1 Y 1 D GLN 49  ? D GLN 49  
515 1 Y 1 D ILE 50  ? D ILE 50  
516 1 Y 1 D LYS 51  ? D LYS 51  
517 1 Y 1 D VAL 52  ? D VAL 52  
518 1 Y 1 D ASN 53  ? D ASN 53  
519 1 Y 1 D LEU 54  ? D LEU 54  
520 1 Y 1 D ASN 55  ? D ASN 55  
521 1 Y 1 D PHE 56  ? D PHE 56  
522 1 Y 1 D ILE 57  ? D ILE 57  
523 1 Y 1 D LYS 58  ? D LYS 58  
524 1 Y 1 D ARG 59  ? D ARG 59  
525 1 Y 1 D PRO 60  ? D PRO 60  
526 1 Y 1 D PRO 61  ? D PRO 61  
527 1 Y 1 D LYS 62  ? D LYS 62  
528 1 Y 1 D ASN 63  ? D ASN 63  
529 1 Y 1 D THR 64  ? D THR 64  
530 1 Y 1 D SER 65  ? D SER 65  
531 1 Y 1 D ALA 66  ? D ALA 66  
532 1 Y 1 D PRO 67  ? D PRO 67  
533 1 Y 1 D SER 68  ? D SER 68  
534 1 Y 1 D GLN 69  ? D GLN 69  
535 1 Y 1 D GLN 70  ? D GLN 70  
536 1 Y 1 D GLU 71  ? D GLU 71  
537 1 Y 1 D PRO 72  ? D PRO 72  
538 1 Y 1 D ASP 73  ? D ASP 73  
539 1 Y 1 D ASP 418 ? D ASP 418 
540 1 Y 1 D GLN 419 ? D GLN 419 
541 1 Y 1 D PRO 420 ? D PRO 420 
542 1 Y 1 D ALA 421 ? D ALA 421 
543 1 Y 1 D ILE 422 ? D ILE 422 
544 1 Y 1 D PRO 423 ? D PRO 423 
545 1 Y 1 D SER 424 ? D SER 424 
546 1 Y 1 D SER 425 ? D SER 425 
547 1 Y 1 D LYS 426 ? D LYS 426 
548 1 Y 1 D ALA 427 ? D ALA 427 
549 1 Y 1 D THR 428 ? D THR 428 
550 1 Y 1 D SER 564 ? D SER 564 
551 1 Y 1 D PRO 565 ? D PRO 565 
552 1 Y 1 D LYS 566 ? D LYS 566 
553 1 Y 1 D ALA 567 ? D ALA 567 
554 1 Y 1 D PRO 568 ? D PRO 568 
555 1 Y 1 D GLU 569 ? D GLU 569 
556 1 Y 1 D ASP 570 ? D ASP 570 
557 1 Y 1 D ASN 571 ? D ASN 571 
558 1 Y 1 D ASN 572 ? D ASN 572 
559 1 Y 1 D SER 573 ? D SER 573 
560 1 Y 1 D THR 574 ? D THR 574 
561 1 Y 1 D VAL 575 ? D VAL 575 
562 1 Y 1 D THR 576 ? D THR 576 
563 1 Y 1 D GLU 577 ? D GLU 577 
564 1 Y 1 D GLN 578 ? D GLN 578 
565 1 Y 1 D PRO 579 ? D PRO 579 
566 1 Y 1 D THR 580 ? D THR 580 
567 1 Y 1 D VAL 581 ? D VAL 581 
568 1 Y 1 D GLY 582 ? D GLY 582 
569 1 Y 1 D GLN 583 ? D GLN 583 
570 1 Y 1 D GLU 584 ? D GLU 584 
571 1 Y 1 D GLU 585 ? D GLU 585 
572 1 Y 1 D GLU 586 ? D GLU 586 
573 1 Y 1 D PRO 587 ? D PRO 587 
574 1 Y 1 D ALA 588 ? D ALA 588 
575 1 Y 1 D GLY 695 ? D GLY 695 
576 1 Y 1 D ASP 696 ? D ASP 696 
577 1 Y 1 D GLY 697 ? D GLY 697 
578 1 Y 1 D THR 698 ? D THR 698 
579 1 Y 1 D PRO 720 ? D PRO 720 
580 1 Y 1 D THR 721 ? D THR 721 
581 1 Y 1 D LEU 722 ? D LEU 722 
582 1 Y 1 D SER 723 ? D SER 723 
583 1 Y 1 D ALA 724 ? D ALA 724 
584 1 Y 1 D ALA 725 ? D ALA 725 
585 1 Y 1 D PRO 726 ? D PRO 726 
586 1 Y 1 D SER 727 ? D SER 727 
587 1 Y 1 D GLY 728 ? D GLY 728 
588 1 Y 1 D PRO 729 ? D PRO 729 
589 1 Y 1 D GLY 730 ? D GLY 730 
590 1 Y 1 D ILE 731 ? D ILE 731 
591 1 Y 1 D THR 732 ? D THR 732 
592 1 Y 1 D GLY 733 ? D GLY 733 
593 1 Y 1 D ASN 734 ? D ASN 734 
594 1 Y 1 D LYS 735 ? D LYS 735 
595 1 Y 1 D LYS 736 ? D LYS 736 
596 1 Y 1 D ASN 737 ? D ASN 737 
597 1 Y 1 D PRO 738 ? D PRO 738 
598 1 Y 1 D THR 739 ? D THR 739 
599 1 Y 1 D SER 740 ? D SER 740 
600 1 Y 1 D LYS 741 ? D LYS 741 
601 1 Y 1 D PRO 742 ? D PRO 742 
602 1 Y 1 D GLY 743 ? D GLY 743 
603 1 Y 1 D LYS 744 ? D LYS 744 
604 1 Y 1 D ASN 745 ? D ASN 745 
605 1 Y 1 D SER 746 ? D SER 746 
606 1 Y 1 D ALA 747 ? D ALA 747 
607 1 Y 1 D SER 748 ? D SER 748 
608 1 Y 1 D GLU 749 ? D GLU 749 
609 1 Y 1 D GLU 750 ? D GLU 750 
610 1 Y 1 D ASP 751 ? D ASP 751 
611 1 Y 1 D HIS 752 ? D HIS 752 
612 1 Y 1 D LEU 753 ? D LEU 753 
613 1 Y 1 D PRO 754 ? D PRO 754 
614 1 Y 1 D LEU 755 ? D LEU 755 
615 1 Y 1 D GLN 756 ? D GLN 756 
616 1 Y 1 D VAL 757 ? D VAL 757 
617 1 Y 1 D LEU 758 ? D LEU 758 
618 1 Y 1 D GLN 759 ? D GLN 759 
619 1 Y 1 D SER 760 ? D SER 760 
620 1 Y 1 D PRO 761 ? D PRO 761 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PEX O1   O N N 247 
PEX O2   O N N 248 
PEX P1   P N N 249 
PEX O3   O N N 250 
PEX C1   C N N 251 
PEX C2   C N R 252 
PEX C3   C N N 253 
PEX O4   O N N 254 
PEX C4   C N N 255 
PEX O5   O N N 256 
PEX C5   C N N 257 
PEX C6   C N N 258 
PEX C7   C N N 259 
PEX C8   C N N 260 
PEX C9   C N N 261 
PEX C10  C N N 262 
PEX C11  C N N 263 
PEX C12  C N N 264 
PEX C13  C N N 265 
PEX O6   O N N 266 
PEX C14  C N N 267 
PEX O7   O N N 268 
PEX C15  C N N 269 
PEX C16  C N N 270 
PEX C17  C N N 271 
PEX C18  C N N 272 
PEX C19  C N N 273 
PEX C20  C N N 274 
PEX C21  C N N 275 
PEX C22  C N N 276 
PEX C23  C N N 277 
PEX O8   O N N 278 
PEX C24  C N N 279 
PEX C25  C N N 280 
PEX N1   N N N 281 
PEX H1   H N N 282 
PEX H2   H N N 283 
PEX H3   H N N 284 
PEX H4   H N N 285 
PEX H5   H N N 286 
PEX H6   H N N 287 
PEX H7   H N N 288 
PEX H8   H N N 289 
PEX H9   H N N 290 
PEX H10  H N N 291 
PEX H11  H N N 292 
PEX H12  H N N 293 
PEX H13  H N N 294 
PEX H14  H N N 295 
PEX H15  H N N 296 
PEX H16  H N N 297 
PEX H17  H N N 298 
PEX H18  H N N 299 
PEX H19  H N N 300 
PEX H20  H N N 301 
PEX H21  H N N 302 
PEX H22  H N N 303 
PEX H23  H N N 304 
PEX H24  H N N 305 
PEX H25  H N N 306 
PEX H26  H N N 307 
PEX H27  H N N 308 
PEX H28  H N N 309 
PEX H29  H N N 310 
PEX H30  H N N 311 
PEX H31  H N N 312 
PEX H32  H N N 313 
PEX H33  H N N 314 
PEX H34  H N N 315 
PEX H35  H N N 316 
PEX H36  H N N 317 
PEX H37  H N N 318 
PEX H38  H N N 319 
PEX H39  H N N 320 
PEX H40  H N N 321 
PEX H41  H N N 322 
PEX H42  H N N 323 
PEX H43  H N N 324 
PEX H44  H N N 325 
PEX H45  H N N 326 
PEX H46  H N N 327 
PEX H47  H N N 328 
PEX H48  H N N 329 
PEX H49  H N N 330 
PHE N    N N N 331 
PHE CA   C N S 332 
PHE C    C N N 333 
PHE O    O N N 334 
PHE CB   C N N 335 
PHE CG   C Y N 336 
PHE CD1  C Y N 337 
PHE CD2  C Y N 338 
PHE CE1  C Y N 339 
PHE CE2  C Y N 340 
PHE CZ   C Y N 341 
PHE OXT  O N N 342 
PHE H    H N N 343 
PHE H2   H N N 344 
PHE HA   H N N 345 
PHE HB2  H N N 346 
PHE HB3  H N N 347 
PHE HD1  H N N 348 
PHE HD2  H N N 349 
PHE HE1  H N N 350 
PHE HE2  H N N 351 
PHE HZ   H N N 352 
PHE HXT  H N N 353 
PRO N    N N N 354 
PRO CA   C N S 355 
PRO C    C N N 356 
PRO O    O N N 357 
PRO CB   C N N 358 
PRO CG   C N N 359 
PRO CD   C N N 360 
PRO OXT  O N N 361 
PRO H    H N N 362 
PRO HA   H N N 363 
PRO HB2  H N N 364 
PRO HB3  H N N 365 
PRO HG2  H N N 366 
PRO HG3  H N N 367 
PRO HD2  H N N 368 
PRO HD3  H N N 369 
PRO HXT  H N N 370 
RTO C13  C Y N 371 
RTO C15  C Y N 372 
RTO C17  C N N 373 
RTO C01  C N N 374 
RTO C02  C N N 375 
RTO C03  C N N 376 
RTO C05  C N N 377 
RTO C06  C N N 378 
RTO C07  C N N 379 
RTO C11  C Y N 380 
RTO C12  C Y N 381 
RTO C14  C Y N 382 
RTO C16  C Y N 383 
RTO N04  N N N 384 
RTO O09  O N N 385 
RTO O10  O N N 386 
RTO O18  O N N 387 
RTO O19  O N N 388 
RTO S08  S N N 389 
RTO H1   H N N 390 
RTO H2   H N N 391 
RTO H3   H N N 392 
RTO H4   H N N 393 
RTO H5   H N N 394 
RTO H6   H N N 395 
RTO H7   H N N 396 
RTO H8   H N N 397 
RTO H9   H N N 398 
RTO H10  H N N 399 
RTO H11  H N N 400 
RTO H12  H N N 401 
RTO H13  H N N 402 
RTO H14  H N N 403 
RTO H15  H N N 404 
RTO H16  H N N 405 
RTO H17  H N N 406 
RTO H18  H N N 407 
RTO H19  H N N 408 
SER N    N N N 409 
SER CA   C N S 410 
SER C    C N N 411 
SER O    O N N 412 
SER CB   C N N 413 
SER OG   O N N 414 
SER OXT  O N N 415 
SER H    H N N 416 
SER H2   H N N 417 
SER HA   H N N 418 
SER HB2  H N N 419 
SER HB3  H N N 420 
SER HG   H N N 421 
SER HXT  H N N 422 
THR N    N N N 423 
THR CA   C N S 424 
THR C    C N N 425 
THR O    O N N 426 
THR CB   C N R 427 
THR OG1  O N N 428 
THR CG2  C N N 429 
THR OXT  O N N 430 
THR H    H N N 431 
THR H2   H N N 432 
THR HA   H N N 433 
THR HB   H N N 434 
THR HG1  H N N 435 
THR HG21 H N N 436 
THR HG22 H N N 437 
THR HG23 H N N 438 
THR HXT  H N N 439 
TRP N    N N N 440 
TRP CA   C N S 441 
TRP C    C N N 442 
TRP O    O N N 443 
TRP CB   C N N 444 
TRP CG   C Y N 445 
TRP CD1  C Y N 446 
TRP CD2  C Y N 447 
TRP NE1  N Y N 448 
TRP CE2  C Y N 449 
TRP CE3  C Y N 450 
TRP CZ2  C Y N 451 
TRP CZ3  C Y N 452 
TRP CH2  C Y N 453 
TRP OXT  O N N 454 
TRP H    H N N 455 
TRP H2   H N N 456 
TRP HA   H N N 457 
TRP HB2  H N N 458 
TRP HB3  H N N 459 
TRP HD1  H N N 460 
TRP HE1  H N N 461 
TRP HE3  H N N 462 
TRP HZ2  H N N 463 
TRP HZ3  H N N 464 
TRP HH2  H N N 465 
TRP HXT  H N N 466 
TYR N    N N N 467 
TYR CA   C N S 468 
TYR C    C N N 469 
TYR O    O N N 470 
TYR CB   C N N 471 
TYR CG   C Y N 472 
TYR CD1  C Y N 473 
TYR CD2  C Y N 474 
TYR CE1  C Y N 475 
TYR CE2  C Y N 476 
TYR CZ   C Y N 477 
TYR OH   O N N 478 
TYR OXT  O N N 479 
TYR H    H N N 480 
TYR H2   H N N 481 
TYR HA   H N N 482 
TYR HB2  H N N 483 
TYR HB3  H N N 484 
TYR HD1  H N N 485 
TYR HD2  H N N 486 
TYR HE1  H N N 487 
TYR HE2  H N N 488 
TYR HH   H N N 489 
TYR HXT  H N N 490 
VAL N    N N N 491 
VAL CA   C N S 492 
VAL C    C N N 493 
VAL O    O N N 494 
VAL CB   C N N 495 
VAL CG1  C N N 496 
VAL CG2  C N N 497 
VAL OXT  O N N 498 
VAL H    H N N 499 
VAL H2   H N N 500 
VAL HA   H N N 501 
VAL HB   H N N 502 
VAL HG11 H N N 503 
VAL HG12 H N N 504 
VAL HG13 H N N 505 
VAL HG21 H N N 506 
VAL HG22 H N N 507 
VAL HG23 H N N 508 
VAL HXT  H N N 509 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PEX O1  P1   sing N N 235 
PEX O2  P1   doub N N 236 
PEX P1  O3   sing N N 237 
PEX P1  O8   sing N N 238 
PEX O3  C1   sing N N 239 
PEX C1  C2   sing N N 240 
PEX C1  H1   sing N N 241 
PEX C1  H2   sing N N 242 
PEX C2  C3   sing N N 243 
PEX C2  O6   sing N N 244 
PEX C2  H3   sing N N 245 
PEX C3  O4   sing N N 246 
PEX C3  H4   sing N N 247 
PEX C3  H5   sing N N 248 
PEX O4  C4   sing N N 249 
PEX C4  O5   doub N N 250 
PEX C4  C5   sing N N 251 
PEX C5  C6   sing N N 252 
PEX C5  H6   sing N N 253 
PEX C5  H7   sing N N 254 
PEX C6  C7   sing N N 255 
PEX C6  H8   sing N N 256 
PEX C6  H9   sing N N 257 
PEX C7  C8   sing N N 258 
PEX C7  H10  sing N N 259 
PEX C7  H11  sing N N 260 
PEX C8  C9   sing N N 261 
PEX C8  H12  sing N N 262 
PEX C8  H13  sing N N 263 
PEX C9  C10  sing N N 264 
PEX C9  H14  sing N N 265 
PEX C9  H15  sing N N 266 
PEX C10 C11  sing N N 267 
PEX C10 H16  sing N N 268 
PEX C10 H17  sing N N 269 
PEX C11 C12  sing N N 270 
PEX C11 H18  sing N N 271 
PEX C11 H19  sing N N 272 
PEX C12 C13  sing N N 273 
PEX C12 H20  sing N N 274 
PEX C12 H21  sing N N 275 
PEX C13 H22  sing N N 276 
PEX C13 H23  sing N N 277 
PEX C13 H24  sing N N 278 
PEX O6  C14  sing N N 279 
PEX C14 O7   doub N N 280 
PEX C14 C15  sing N N 281 
PEX C15 C16  sing N N 282 
PEX C15 H25  sing N N 283 
PEX C15 H26  sing N N 284 
PEX C16 C17  sing N N 285 
PEX C16 H27  sing N N 286 
PEX C16 H28  sing N N 287 
PEX C17 C18  sing N N 288 
PEX C17 H29  sing N N 289 
PEX C17 H30  sing N N 290 
PEX C18 C19  sing N N 291 
PEX C18 H31  sing N N 292 
PEX C18 H32  sing N N 293 
PEX C19 C20  sing N N 294 
PEX C19 H33  sing N N 295 
PEX C19 H34  sing N N 296 
PEX C20 C21  sing N N 297 
PEX C20 H35  sing N N 298 
PEX C20 H36  sing N N 299 
PEX C21 C22  sing N N 300 
PEX C21 H37  sing N N 301 
PEX C21 H38  sing N N 302 
PEX C22 C23  sing N N 303 
PEX C22 H39  sing N N 304 
PEX C22 H40  sing N N 305 
PEX C23 H41  sing N N 306 
PEX C23 H42  sing N N 307 
PEX C23 H43  sing N N 308 
PEX O8  C24  sing N N 309 
PEX C24 C25  sing N N 310 
PEX C24 H44  sing N N 311 
PEX C24 H45  sing N N 312 
PEX C25 N1   sing N N 313 
PEX C25 H46  sing N N 314 
PEX C25 H47  sing N N 315 
PEX N1  H48  sing N N 316 
PEX N1  H49  sing N N 317 
PHE N   CA   sing N N 318 
PHE N   H    sing N N 319 
PHE N   H2   sing N N 320 
PHE CA  C    sing N N 321 
PHE CA  CB   sing N N 322 
PHE CA  HA   sing N N 323 
PHE C   O    doub N N 324 
PHE C   OXT  sing N N 325 
PHE CB  CG   sing N N 326 
PHE CB  HB2  sing N N 327 
PHE CB  HB3  sing N N 328 
PHE CG  CD1  doub Y N 329 
PHE CG  CD2  sing Y N 330 
PHE CD1 CE1  sing Y N 331 
PHE CD1 HD1  sing N N 332 
PHE CD2 CE2  doub Y N 333 
PHE CD2 HD2  sing N N 334 
PHE CE1 CZ   doub Y N 335 
PHE CE1 HE1  sing N N 336 
PHE CE2 CZ   sing Y N 337 
PHE CE2 HE2  sing N N 338 
PHE CZ  HZ   sing N N 339 
PHE OXT HXT  sing N N 340 
PRO N   CA   sing N N 341 
PRO N   CD   sing N N 342 
PRO N   H    sing N N 343 
PRO CA  C    sing N N 344 
PRO CA  CB   sing N N 345 
PRO CA  HA   sing N N 346 
PRO C   O    doub N N 347 
PRO C   OXT  sing N N 348 
PRO CB  CG   sing N N 349 
PRO CB  HB2  sing N N 350 
PRO CB  HB3  sing N N 351 
PRO CG  CD   sing N N 352 
PRO CG  HG2  sing N N 353 
PRO CG  HG3  sing N N 354 
PRO CD  HD2  sing N N 355 
PRO CD  HD3  sing N N 356 
PRO OXT HXT  sing N N 357 
RTO C07 C06  sing N N 358 
RTO C06 C05  sing N N 359 
RTO O10 S08  doub N N 360 
RTO C12 C13  doub Y N 361 
RTO C12 C11  sing Y N 362 
RTO C13 C14  sing Y N 363 
RTO O19 C17  doub N N 364 
RTO S08 C11  sing N N 365 
RTO S08 N04  sing N N 366 
RTO S08 O09  doub N N 367 
RTO C05 N04  sing N N 368 
RTO C11 C16  doub Y N 369 
RTO N04 C03  sing N N 370 
RTO C14 C17  sing N N 371 
RTO C14 C15  doub Y N 372 
RTO C17 O18  sing N N 373 
RTO C03 C02  sing N N 374 
RTO C16 C15  sing Y N 375 
RTO C02 C01  sing N N 376 
RTO C13 H1   sing N N 377 
RTO C15 H2   sing N N 378 
RTO C01 H3   sing N N 379 
RTO C01 H4   sing N N 380 
RTO C01 H5   sing N N 381 
RTO C02 H6   sing N N 382 
RTO C02 H7   sing N N 383 
RTO C03 H8   sing N N 384 
RTO C03 H9   sing N N 385 
RTO C05 H10  sing N N 386 
RTO C05 H11  sing N N 387 
RTO C06 H12  sing N N 388 
RTO C06 H13  sing N N 389 
RTO C07 H14  sing N N 390 
RTO C07 H15  sing N N 391 
RTO C07 H16  sing N N 392 
RTO C12 H17  sing N N 393 
RTO C16 H18  sing N N 394 
RTO O18 H19  sing N N 395 
SER N   CA   sing N N 396 
SER N   H    sing N N 397 
SER N   H2   sing N N 398 
SER CA  C    sing N N 399 
SER CA  CB   sing N N 400 
SER CA  HA   sing N N 401 
SER C   O    doub N N 402 
SER C   OXT  sing N N 403 
SER CB  OG   sing N N 404 
SER CB  HB2  sing N N 405 
SER CB  HB3  sing N N 406 
SER OG  HG   sing N N 407 
SER OXT HXT  sing N N 408 
THR N   CA   sing N N 409 
THR N   H    sing N N 410 
THR N   H2   sing N N 411 
THR CA  C    sing N N 412 
THR CA  CB   sing N N 413 
THR CA  HA   sing N N 414 
THR C   O    doub N N 415 
THR C   OXT  sing N N 416 
THR CB  OG1  sing N N 417 
THR CB  CG2  sing N N 418 
THR CB  HB   sing N N 419 
THR OG1 HG1  sing N N 420 
THR CG2 HG21 sing N N 421 
THR CG2 HG22 sing N N 422 
THR CG2 HG23 sing N N 423 
THR OXT HXT  sing N N 424 
TRP N   CA   sing N N 425 
TRP N   H    sing N N 426 
TRP N   H2   sing N N 427 
TRP CA  C    sing N N 428 
TRP CA  CB   sing N N 429 
TRP CA  HA   sing N N 430 
TRP C   O    doub N N 431 
TRP C   OXT  sing N N 432 
TRP CB  CG   sing N N 433 
TRP CB  HB2  sing N N 434 
TRP CB  HB3  sing N N 435 
TRP CG  CD1  doub Y N 436 
TRP CG  CD2  sing Y N 437 
TRP CD1 NE1  sing Y N 438 
TRP CD1 HD1  sing N N 439 
TRP CD2 CE2  doub Y N 440 
TRP CD2 CE3  sing Y N 441 
TRP NE1 CE2  sing Y N 442 
TRP NE1 HE1  sing N N 443 
TRP CE2 CZ2  sing Y N 444 
TRP CE3 CZ3  doub Y N 445 
TRP CE3 HE3  sing N N 446 
TRP CZ2 CH2  doub Y N 447 
TRP CZ2 HZ2  sing N N 448 
TRP CZ3 CH2  sing Y N 449 
TRP CZ3 HZ3  sing N N 450 
TRP CH2 HH2  sing N N 451 
TRP OXT HXT  sing N N 452 
TYR N   CA   sing N N 453 
TYR N   H    sing N N 454 
TYR N   H2   sing N N 455 
TYR CA  C    sing N N 456 
TYR CA  CB   sing N N 457 
TYR CA  HA   sing N N 458 
TYR C   O    doub N N 459 
TYR C   OXT  sing N N 460 
TYR CB  CG   sing N N 461 
TYR CB  HB2  sing N N 462 
TYR CB  HB3  sing N N 463 
TYR CG  CD1  doub Y N 464 
TYR CG  CD2  sing Y N 465 
TYR CD1 CE1  sing Y N 466 
TYR CD1 HD1  sing N N 467 
TYR CD2 CE2  doub Y N 468 
TYR CD2 HD2  sing N N 469 
TYR CE1 CZ   doub Y N 470 
TYR CE1 HE1  sing N N 471 
TYR CE2 CZ   sing Y N 472 
TYR CE2 HE2  sing N N 473 
TYR CZ  OH   sing N N 474 
TYR OH  HH   sing N N 475 
TYR OXT HXT  sing N N 476 
VAL N   CA   sing N N 477 
VAL N   H    sing N N 478 
VAL N   H2   sing N N 479 
VAL CA  C    sing N N 480 
VAL CA  CB   sing N N 481 
VAL CA  HA   sing N N 482 
VAL C   O    doub N N 483 
VAL C   OXT  sing N N 484 
VAL CB  CG1  sing N N 485 
VAL CB  CG2  sing N N 486 
VAL CB  HB   sing N N 487 
VAL CG1 HG11 sing N N 488 
VAL CG1 HG12 sing N N 489 
VAL CG1 HG13 sing N N 490 
VAL CG2 HG21 sing N N 491 
VAL CG2 HG22 sing N N 492 
VAL CG2 HG23 sing N N 493 
VAL OXT HXT  sing N N 494 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-03-20 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9B3Y 
_em_admin.last_update        2025-03-05 
_em_admin.map_release_date   2025-02-26 
_em_admin.title              'Rat TRPV2 E724A/D725A bound to probenecid' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          10116 
_em_entity_assembly_naturalsource.organism             'Rattus norvegicus' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          4932 
_em_entity_assembly_recombinant.organism             'Saccharomyces cerevisiae' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         41.3 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'MODEL REFINEMENT'              ? 1  ? ? ? PHENIX 1.20.1_4487: 
'IMAGE ACQUISITION'             ? 2  1 1 1 ?      ?            
'PARTICLE SELECTION'            ? 3  1 1 1 ?      ?            
'VOLUME SELECTION'              ? 4  1 1 1 ?      ?            
CLASSIFICATION                  ? 5  1 1 1 ?      ?            
MASKING                         ? 6  1 1 1 ?      ?            
RECONSTRUCTION                  ? 7  1 1 1 ?      ?            
'INITIAL EULER ASSIGNMENT'      ? 8  1 1 1 ?      ?            
'FINAL EULER ASSIGNMENT'        ? 9  1 1 1 ?      ?            
'CTF CORRECTION'                ? 10 1 1 1 ?      ?            
'LAYERLINE INDEXING'            ? 11 1 1 1 ?      ?            
'DIFFRACTION INDEXING'          ? 12 1 1 1 ?      ?            
'MODEL FITTING'                 ? 13 1 1 1 ?      ?            
'SERIES ALIGNMENT'              ? 14 1 1 1 ?      ?            
'MOLECULAR REPLACEMENT'         ? 15 1 1 1 ?      ?            
'LATTICE DISTORTION CORRECTION' ? 16 1 1 1 ?      ?            
'SYMMETRY DETERMINATION'        ? 17 1 1 1 ?      ?            
'CRYSTALLOGRAPHY MERGING'       ? 18 1 1 1 ?      ?            
OTHER                           ? 19 1 1 1 ?      ?            
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           R35GM144120 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9B3Y 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . ARG A 1 74  ? 174.397 83.849  89.221  1.00 168.48 ? 74  ARG A N   1 
ATOM   2     C CA  . ARG A 1 74  ? 174.204 83.116  90.501  1.00 168.86 ? 74  ARG A CA  1 
ATOM   3     C C   . ARG A 1 74  ? 172.703 83.018  90.796  1.00 170.27 ? 74  ARG A C   1 
ATOM   4     O O   . ARG A 1 74  ? 172.281 81.901  91.152  1.00 170.55 ? 74  ARG A O   1 
ATOM   5     C CB  . ARG A 1 74  ? 174.982 83.815  91.636  1.00 168.45 ? 74  ARG A CB  1 
ATOM   6     N N   . PHE A 1 75  ? 171.904 84.089  90.682  1.00 167.79 ? 75  PHE A N   1 
ATOM   7     C CA  . PHE A 1 75  ? 170.477 84.104  91.095  1.00 166.40 ? 75  PHE A CA  1 
ATOM   8     C C   . PHE A 1 75  ? 170.227 83.704  92.565  1.00 165.82 ? 75  PHE A C   1 
ATOM   9     O O   . PHE A 1 75  ? 169.304 82.961  92.904  1.00 165.60 ? 75  PHE A O   1 
ATOM   10    C CB  . PHE A 1 75  ? 169.576 83.373  90.086  1.00 166.49 ? 75  PHE A CB  1 
ATOM   11    C CG  . PHE A 1 75  ? 169.368 84.144  88.803  1.00 167.45 ? 75  PHE A CG  1 
ATOM   12    C CD1 . PHE A 1 75  ? 168.576 85.308  88.809  1.00 166.84 ? 75  PHE A CD1 1 
ATOM   13    C CD2 . PHE A 1 75  ? 169.966 83.711  87.606  1.00 166.78 ? 75  PHE A CD2 1 
ATOM   14    C CE1 . PHE A 1 75  ? 168.379 86.036  87.625  1.00 166.99 ? 75  PHE A CE1 1 
ATOM   15    C CE2 . PHE A 1 75  ? 169.777 84.445  86.426  1.00 166.30 ? 75  PHE A CE2 1 
ATOM   16    C CZ  . PHE A 1 75  ? 168.979 85.600  86.432  1.00 166.85 ? 75  PHE A CZ  1 
ATOM   17    N N   . ASP A 1 76  ? 171.015 84.248  93.373  1.00 161.82 ? 76  ASP A N   1 
ATOM   18    C CA  . ASP A 1 76  ? 170.680 84.344  94.794  1.00 161.88 ? 76  ASP A CA  1 
ATOM   19    C C   . ASP A 1 76  ? 169.547 85.366  95.041  1.00 162.31 ? 76  ASP A C   1 
ATOM   20    O O   . ASP A 1 76  ? 169.106 86.091  94.139  1.00 162.20 ? 76  ASP A O   1 
ATOM   21    C CB  . ASP A 1 76  ? 171.956 84.658  95.602  1.00 160.98 ? 76  ASP A CB  1 
ATOM   22    C CG  . ASP A 1 76  ? 172.697 85.952  95.220  1.00 161.24 ? 76  ASP A CG  1 
ATOM   23    O OD1 . ASP A 1 76  ? 172.093 86.858  94.613  1.00 161.92 ? 76  ASP A OD1 1 
ATOM   24    O OD2 . ASP A 1 76  ? 173.902 86.041  95.545  1.00 159.88 ? 76  ASP A OD2 1 
ATOM   25    N N   . ARG A 1 77  ? 169.122 85.457  96.307  1.00 152.29 ? 77  ARG A N   1 
ATOM   26    C CA  . ARG A 1 77  ? 168.013 86.372  96.697  1.00 153.02 ? 77  ARG A CA  1 
ATOM   27    C C   . ARG A 1 77  ? 168.361 87.835  96.430  1.00 152.39 ? 77  ARG A C   1 
ATOM   28    O O   . ARG A 1 77  ? 167.471 88.571  95.960  1.00 152.53 ? 77  ARG A O   1 
ATOM   29    C CB  . ARG A 1 77  ? 167.765 86.217  98.202  1.00 150.72 ? 77  ARG A CB  1 
ATOM   30    C CG  . ARG A 1 77  ? 166.603 87.086  98.706  1.00 152.66 ? 77  ARG A CG  1 
ATOM   31    C CD  . ARG A 1 77  ? 166.602 87.202  100.227 1.00 152.24 ? 77  ARG A CD  1 
ATOM   32    N NE  . ARG A 1 77  ? 167.757 87.978  100.704 1.00 152.20 ? 77  ARG A NE  1 
ATOM   33    C CZ  . ARG A 1 77  ? 167.965 88.313  101.972 1.00 151.69 ? 77  ARG A CZ  1 
ATOM   34    N NH1 . ARG A 1 77  ? 169.036 89.014  102.303 1.00 150.82 ? 77  ARG A NH1 1 
ATOM   35    N NH2 . ARG A 1 77  ? 167.101 87.950  102.903 1.00 150.21 ? 77  ARG A NH2 1 
ATOM   36    N N   . ASP A 1 78  ? 169.599 88.241  96.710  1.00 152.83 ? 78  ASP A N   1 
ATOM   37    C CA  . ASP A 1 78  ? 169.983 89.649  96.617  1.00 152.68 ? 78  ASP A CA  1 
ATOM   38    C C   . ASP A 1 78  ? 170.088 90.126  95.155  1.00 152.32 ? 78  ASP A C   1 
ATOM   39    O O   . ASP A 1 78  ? 169.693 91.260  94.852  1.00 153.06 ? 78  ASP A O   1 
ATOM   40    C CB  . ASP A 1 78  ? 171.270 89.893  97.414  1.00 154.38 ? 78  ASP A CB  1 
ATOM   41    C CG  . ASP A 1 78  ? 171.177 89.542  98.913  1.00 155.02 ? 78  ASP A CG  1 
ATOM   42    O OD1 . ASP A 1 78  ? 170.068 89.353  99.467  1.00 156.02 ? 78  ASP A OD1 1 
ATOM   43    O OD2 . ASP A 1 78  ? 172.247 89.478  99.560  1.00 153.83 ? 78  ASP A OD2 1 
ATOM   44    N N   . ARG A 1 79  ? 170.479 89.258  94.205  1.00 156.28 ? 79  ARG A N   1 
ATOM   45    C CA  . ARG A 1 79  ? 170.263 89.539  92.774  1.00 158.03 ? 79  ARG A CA  1 
ATOM   46    C C   . ARG A 1 79  ? 168.773 89.640  92.463  1.00 158.93 ? 79  ARG A C   1 
ATOM   47    O O   . ARG A 1 79  ? 168.345 90.644  91.909  1.00 157.44 ? 79  ARG A O   1 
ATOM   48    C CB  . ARG A 1 79  ? 170.954 88.508  91.855  1.00 157.76 ? 79  ARG A CB  1 
ATOM   49    C CG  . ARG A 1 79  ? 170.706 88.864  90.373  1.00 158.69 ? 79  ARG A CG  1 
ATOM   50    C CD  . ARG A 1 79  ? 171.358 87.899  89.380  1.00 157.88 ? 79  ARG A CD  1 
ATOM   51    N NE  . ARG A 1 79  ? 170.873 88.135  88.003  1.00 158.99 ? 79  ARG A NE  1 
ATOM   52    C CZ  . ARG A 1 79  ? 171.306 89.035  87.138  1.00 157.86 ? 79  ARG A CZ  1 
ATOM   53    N NH1 . ARG A 1 79  ? 170.720 89.184  85.987  1.00 157.52 ? 79  ARG A NH1 1 
ATOM   54    N NH2 . ARG A 1 79  ? 172.318 89.809  87.392  1.00 156.82 ? 79  ARG A NH2 1 
ATOM   55    N N   . LEU A 1 80  ? 167.965 88.635  92.803  1.00 154.57 ? 80  LEU A N   1 
ATOM   56    C CA  . LEU A 1 80  ? 166.556 88.634  92.399  1.00 152.06 ? 80  LEU A CA  1 
ATOM   57    C C   . LEU A 1 80  ? 165.780 89.840  92.956  1.00 151.87 ? 80  LEU A C   1 
ATOM   58    O O   . LEU A 1 80  ? 165.072 90.514  92.215  1.00 152.02 ? 80  LEU A O   1 
ATOM   59    C CB  . LEU A 1 80  ? 165.904 87.298  92.787  1.00 151.79 ? 80  LEU A CB  1 
ATOM   60    C CG  . LEU A 1 80  ? 164.426 87.200  92.373  1.00 152.15 ? 80  LEU A CG  1 
ATOM   61    C CD1 . LEU A 1 80  ? 164.231 87.412  90.879  1.00 152.64 ? 80  LEU A CD1 1 
ATOM   62    C CD2 . LEU A 1 80  ? 163.899 85.816  92.718  1.00 151.57 ? 80  LEU A CD2 1 
ATOM   63    N N   . PHE A 1 81  ? 165.955 90.162  94.237  1.00 144.75 ? 81  PHE A N   1 
ATOM   64    C CA  . PHE A 1 81  ? 165.289 91.290  94.889  1.00 143.59 ? 81  PHE A CA  1 
ATOM   65    C C   . PHE A 1 81  ? 165.722 92.636  94.301  1.00 144.20 ? 81  PHE A C   1 
ATOM   66    O O   . PHE A 1 81  ? 164.911 93.555  94.219  1.00 145.01 ? 81  PHE A O   1 
ATOM   67    C CB  . PHE A 1 81  ? 165.578 91.273  96.396  1.00 143.82 ? 81  PHE A CB  1 
ATOM   68    C CG  . PHE A 1 81  ? 164.759 90.318  97.249  1.00 145.67 ? 81  PHE A CG  1 
ATOM   69    C CD1 . PHE A 1 81  ? 164.211 89.123  96.742  1.00 145.86 ? 81  PHE A CD1 1 
ATOM   70    C CD2 . PHE A 1 81  ? 164.550 90.644  98.598  1.00 144.08 ? 81  PHE A CD2 1 
ATOM   71    C CE1 . PHE A 1 81  ? 163.467 88.274  97.577  1.00 145.65 ? 81  PHE A CE1 1 
ATOM   72    C CE2 . PHE A 1 81  ? 163.799 89.799  99.427  1.00 143.96 ? 81  PHE A CE2 1 
ATOM   73    C CZ  . PHE A 1 81  ? 163.254 88.615  98.917  1.00 145.38 ? 81  PHE A CZ  1 
ATOM   74    N N   . SER A 1 82  ? 166.974 92.784  93.861  1.00 150.25 ? 82  SER A N   1 
ATOM   75    C CA  . SER A 1 82  ? 167.404 94.001  93.158  1.00 149.77 ? 82  SER A CA  1 
ATOM   76    C C   . SER A 1 82  ? 166.927 94.029  91.691  1.00 149.46 ? 82  SER A C   1 
ATOM   77    O O   . SER A 1 82  ? 166.545 95.091  91.204  1.00 148.02 ? 82  SER A O   1 
ATOM   78    C CB  . SER A 1 82  ? 168.913 94.213  93.313  1.00 148.64 ? 82  SER A CB  1 
ATOM   79    O OG  . SER A 1 82  ? 169.678 93.139  92.819  1.00 149.29 ? 82  SER A OG  1 
ATOM   80    N N   . VAL A 1 83  ? 166.816 92.881  91.010  1.00 148.73 ? 83  VAL A N   1 
ATOM   81    C CA  . VAL A 1 83  ? 166.240 92.765  89.651  1.00 148.38 ? 83  VAL A CA  1 
ATOM   82    C C   . VAL A 1 83  ? 164.765 93.169  89.605  1.00 148.44 ? 83  VAL A C   1 
ATOM   83    O O   . VAL A 1 83  ? 164.402 94.082  88.862  1.00 146.48 ? 83  VAL A O   1 
ATOM   84    C CB  . VAL A 1 83  ? 166.448 91.343  89.080  1.00 148.13 ? 83  VAL A CB  1 
ATOM   85    C CG1 . VAL A 1 83  ? 165.578 91.029  87.857  1.00 148.82 ? 83  VAL A CG1 1 
ATOM   86    C CG2 . VAL A 1 83  ? 167.906 91.153  88.647  1.00 148.71 ? 83  VAL A CG2 1 
ATOM   87    N N   . VAL A 1 84  ? 163.902 92.557  90.425  1.00 146.41 ? 84  VAL A N   1 
ATOM   88    C CA  . VAL A 1 84  ? 162.456 92.866  90.403  1.00 144.17 ? 84  VAL A CA  1 
ATOM   89    C C   . VAL A 1 84  ? 162.137 94.289  90.874  1.00 143.65 ? 84  VAL A C   1 
ATOM   90    O O   . VAL A 1 84  ? 161.095 94.830  90.506  1.00 142.74 ? 84  VAL A O   1 
ATOM   91    C CB  . VAL A 1 84  ? 161.618 91.843  91.185  1.00 143.89 ? 84  VAL A CB  1 
ATOM   92    C CG1 . VAL A 1 84  ? 161.813 90.431  90.638  1.00 143.83 ? 84  VAL A CG1 1 
ATOM   93    C CG2 . VAL A 1 84  ? 161.880 91.857  92.691  1.00 142.29 ? 84  VAL A CG2 1 
ATOM   94    N N   . SER A 1 85  ? 163.038 94.930  91.632  1.00 144.34 ? 85  SER A N   1 
ATOM   95    C CA  . SER A 1 85  ? 162.881 96.335  92.038  1.00 144.57 ? 85  SER A CA  1 
ATOM   96    C C   . SER A 1 85  ? 163.085 97.335  90.889  1.00 142.52 ? 85  SER A C   1 
ATOM   97    O O   . SER A 1 85  ? 162.506 98.416  90.928  1.00 139.37 ? 85  SER A O   1 
ATOM   98    C CB  . SER A 1 85  ? 163.857 96.687  93.164  1.00 142.66 ? 85  SER A CB  1 
ATOM   99    O OG  . SER A 1 85  ? 163.649 95.881  94.310  1.00 141.96 ? 85  SER A OG  1 
ATOM   100   N N   . ARG A 1 86  ? 163.850 96.943  89.854  1.00 150.85 ? 86  ARG A N   1 
ATOM   101   C CA  . ARG A 1 86  ? 164.157 97.842  88.696  1.00 151.89 ? 86  ARG A CA  1 
ATOM   102   C C   . ARG A 1 86  ? 163.010 97.850  87.677  1.00 152.15 ? 86  ARG A C   1 
ATOM   103   O O   . ARG A 1 86  ? 162.912 98.836  86.921  1.00 150.76 ? 86  ARG A O   1 
ATOM   104   C CB  . ARG A 1 86  ? 165.471 97.425  88.009  1.00 150.48 ? 86  ARG A CB  1 
ATOM   105   C CG  . ARG A 1 86  ? 166.708 97.863  88.804  1.00 150.09 ? 86  ARG A CG  1 
ATOM   106   C CD  . ARG A 1 86  ? 168.003 97.654  88.005  1.00 149.41 ? 86  ARG A CD  1 
ATOM   107   N NE  . ARG A 1 86  ? 168.385 96.234  87.870  1.00 150.26 ? 86  ARG A NE  1 
ATOM   108   C CZ  . ARG A 1 86  ? 168.963 95.514  88.825  1.00 150.99 ? 86  ARG A CZ  1 
ATOM   109   N NH1 . ARG A 1 86  ? 169.266 94.246  88.605  1.00 148.99 ? 86  ARG A NH1 1 
ATOM   110   N NH2 . ARG A 1 86  ? 169.230 96.060  89.997  1.00 151.28 ? 86  ARG A NH2 1 
ATOM   111   N N   . GLY A 1 87  ? 162.185 96.805  87.654  1.00 153.16 ? 87  GLY A N   1 
ATOM   112   C CA  . GLY A 1 87  ? 161.076 96.669  86.701  1.00 150.66 ? 87  GLY A CA  1 
ATOM   113   C C   . GLY A 1 87  ? 161.481 96.175  85.305  1.00 152.76 ? 87  GLY A C   1 
ATOM   114   O O   . GLY A 1 87  ? 160.658 96.205  84.393  1.00 150.84 ? 87  GLY A O   1 
ATOM   115   N N   . VAL A 1 88  ? 162.724 95.712  85.120  1.00 162.08 ? 88  VAL A N   1 
ATOM   116   C CA  . VAL A 1 88  ? 163.218 95.142  83.853  1.00 162.16 ? 88  VAL A CA  1 
ATOM   117   C C   . VAL A 1 88  ? 163.079 93.610  83.884  1.00 161.67 ? 88  VAL A C   1 
ATOM   118   O O   . VAL A 1 88  ? 163.781 92.959  84.658  1.00 159.71 ? 88  VAL A O   1 
ATOM   119   C CB  . VAL A 1 88  ? 164.685 95.552  83.599  1.00 159.88 ? 88  VAL A CB  1 
ATOM   120   C CG1 . VAL A 1 88  ? 165.221 94.956  82.293  1.00 158.45 ? 88  VAL A CG1 1 
ATOM   121   C CG2 . VAL A 1 88  ? 164.819 97.074  83.504  1.00 158.01 ? 88  VAL A CG2 1 
ATOM   122   N N   . PRO A 1 89  ? 162.214 92.997  83.052  1.00 159.88 ? 89  PRO A N   1 
ATOM   123   C CA  . PRO A 1 89  ? 161.953 91.558  83.121  1.00 158.93 ? 89  PRO A CA  1 
ATOM   124   C C   . PRO A 1 89  ? 163.091 90.706  82.546  1.00 159.23 ? 89  PRO A C   1 
ATOM   125   O O   . PRO A 1 89  ? 163.267 89.554  82.933  1.00 157.55 ? 89  PRO A O   1 
ATOM   126   C CB  . PRO A 1 89  ? 160.663 91.355  82.323  1.00 158.39 ? 89  PRO A CB  1 
ATOM   127   C CG  . PRO A 1 89  ? 160.672 92.494  81.308  1.00 158.14 ? 89  PRO A CG  1 
ATOM   128   C CD  . PRO A 1 89  ? 161.341 93.632  82.072  1.00 157.81 ? 89  PRO A CD  1 
ATOM   129   N N   . GLU A 1 90  ? 163.876 91.251  81.616  1.00 163.61 ? 90  GLU A N   1 
ATOM   130   C CA  . GLU A 1 90  ? 164.868 90.477  80.853  1.00 162.84 ? 90  GLU A CA  1 
ATOM   131   C C   . GLU A 1 90  ? 166.046 89.979  81.711  1.00 163.88 ? 90  GLU A C   1 
ATOM   132   O O   . GLU A 1 90  ? 166.631 88.931  81.435  1.00 163.70 ? 90  GLU A O   1 
ATOM   133   C CB  . GLU A 1 90  ? 165.389 91.330  79.685  1.00 160.58 ? 90  GLU A CB  1 
ATOM   134   N N   . GLU A 1 91  ? 166.371 90.679  82.801  1.00 164.32 ? 91  GLU A N   1 
ATOM   135   C CA  . GLU A 1 91  ? 167.443 90.298  83.731  1.00 163.19 ? 91  GLU A CA  1 
ATOM   136   C C   . GLU A 1 91  ? 167.132 89.033  84.562  1.00 163.63 ? 91  GLU A C   1 
ATOM   137   O O   . GLU A 1 91  ? 168.023 88.510  85.233  1.00 163.04 ? 91  GLU A O   1 
ATOM   138   C CB  . GLU A 1 91  ? 167.788 91.489  84.641  1.00 163.43 ? 91  GLU A CB  1 
ATOM   139   C CG  . GLU A 1 91  ? 168.343 92.681  83.849  1.00 163.68 ? 91  GLU A CG  1 
ATOM   140   C CD  . GLU A 1 91  ? 169.084 93.693  84.735  1.00 164.38 ? 91  GLU A CD  1 
ATOM   141   O OE1 . GLU A 1 91  ? 168.574 94.073  85.812  1.00 163.80 ? 91  GLU A OE1 1 
ATOM   142   O OE2 . GLU A 1 91  ? 170.198 94.111  84.349  1.00 163.68 ? 91  GLU A OE2 1 
ATOM   143   N N   . LEU A 1 92  ? 165.903 88.504  84.481  1.00 164.92 ? 92  LEU A N   1 
ATOM   144   C CA  . LEU A 1 92  ? 165.516 87.197  85.028  1.00 165.36 ? 92  LEU A CA  1 
ATOM   145   C C   . LEU A 1 92  ? 166.030 86.012  84.180  1.00 164.13 ? 92  LEU A C   1 
ATOM   146   O O   . LEU A 1 92  ? 165.870 84.856  84.573  1.00 163.64 ? 92  LEU A O   1 
ATOM   147   C CB  . LEU A 1 92  ? 163.977 87.134  85.163  1.00 164.77 ? 92  LEU A CB  1 
ATOM   148   C CG  . LEU A 1 92  ? 163.346 88.185  86.094  1.00 164.40 ? 92  LEU A CG  1 
ATOM   149   C CD1 . LEU A 1 92  ? 161.828 88.222  85.923  1.00 164.36 ? 92  LEU A CD1 1 
ATOM   150   C CD2 . LEU A 1 92  ? 163.640 87.866  87.559  1.00 162.78 ? 92  LEU A CD2 1 
ATOM   151   N N   . THR A 1 93  ? 166.633 86.263  83.011  1.00 167.27 ? 93  THR A N   1 
ATOM   152   C CA  . THR A 1 93  ? 167.098 85.215  82.080  1.00 168.41 ? 93  THR A CA  1 
ATOM   153   C C   . THR A 1 93  ? 168.097 84.261  82.751  1.00 168.85 ? 93  THR A C   1 
ATOM   154   O O   . THR A 1 93  ? 169.185 84.670  83.153  1.00 169.47 ? 93  THR A O   1 
ATOM   155   C CB  . THR A 1 93  ? 167.713 85.831  80.813  1.00 166.69 ? 93  THR A CB  1 
ATOM   156   O OG1 . THR A 1 93  ? 166.744 86.589  80.130  1.00 166.49 ? 93  THR A OG1 1 
ATOM   157   C CG2 . THR A 1 93  ? 168.200 84.777  79.820  1.00 166.21 ? 93  THR A CG2 1 
ATOM   158   N N   . GLY A 1 94  ? 167.731 82.982  82.869  1.00 170.30 ? 94  GLY A N   1 
ATOM   159   C CA  . GLY A 1 94  ? 168.514 81.942  83.545  1.00 170.34 ? 94  GLY A CA  1 
ATOM   160   C C   . GLY A 1 94  ? 168.049 81.577  84.963  1.00 171.12 ? 94  GLY A C   1 
ATOM   161   O O   . GLY A 1 94  ? 168.512 80.573  85.508  1.00 170.58 ? 94  GLY A O   1 
ATOM   162   N N   . LEU A 1 95  ? 167.098 82.314  85.552  1.00 170.01 ? 95  LEU A N   1 
ATOM   163   C CA  . LEU A 1 95  ? 166.545 81.985  86.872  1.00 169.67 ? 95  LEU A CA  1 
ATOM   164   C C   . LEU A 1 95  ? 165.864 80.604  86.885  1.00 169.52 ? 95  LEU A C   1 
ATOM   165   O O   . LEU A 1 95  ? 166.023 79.850  87.842  1.00 169.80 ? 95  LEU A O   1 
ATOM   166   C CB  . LEU A 1 95  ? 165.588 83.117  87.294  1.00 169.12 ? 95  LEU A CB  1 
ATOM   167   C CG  . LEU A 1 95  ? 164.866 82.923  88.644  1.00 169.26 ? 95  LEU A CG  1 
ATOM   168   C CD1 . LEU A 1 95  ? 165.827 82.776  89.818  1.00 168.56 ? 95  LEU A CD1 1 
ATOM   169   C CD2 . LEU A 1 95  ? 163.999 84.148  88.923  1.00 168.56 ? 95  LEU A CD2 1 
ATOM   170   N N   . LEU A 1 96  ? 165.177 80.234  85.792  1.00 168.90 ? 96  LEU A N   1 
ATOM   171   C CA  . LEU A 1 96  ? 164.575 78.903  85.635  1.00 168.66 ? 96  LEU A CA  1 
ATOM   172   C C   . LEU A 1 96  ? 165.625 77.795  85.773  1.00 169.90 ? 96  LEU A C   1 
ATOM   173   O O   . LEU A 1 96  ? 165.435 76.832  86.513  1.00 169.49 ? 96  LEU A O   1 
ATOM   174   C CB  . LEU A 1 96  ? 163.890 78.746  84.261  1.00 169.72 ? 96  LEU A CB  1 
ATOM   175   C CG  . LEU A 1 96  ? 162.745 79.719  83.938  1.00 169.53 ? 96  LEU A CG  1 
ATOM   176   C CD1 . LEU A 1 96  ? 163.252 81.014  83.293  1.00 169.28 ? 96  LEU A CD1 1 
ATOM   177   C CD2 . LEU A 1 96  ? 161.773 79.069  82.958  1.00 168.05 ? 96  LEU A CD2 1 
ATOM   178   N N   . GLU A 1 97  ? 166.749 77.927  85.065  1.00 172.75 ? 97  GLU A N   1 
ATOM   179   C CA  . GLU A 1 97  ? 167.820 76.927  85.068  1.00 171.98 ? 97  GLU A CA  1 
ATOM   180   C C   . GLU A 1 97  ? 168.458 76.791  86.452  1.00 172.68 ? 97  GLU A C   1 
ATOM   181   O O   . GLU A 1 97  ? 168.678 75.674  86.913  1.00 170.83 ? 97  GLU A O   1 
ATOM   182   C CB  . GLU A 1 97  ? 168.897 77.285  84.036  1.00 169.59 ? 97  GLU A CB  1 
ATOM   183   N N   . TYR A 1 98  ? 168.707 77.904  87.148  1.00 173.59 ? 98  TYR A N   1 
ATOM   184   C CA  . TYR A 1 98  ? 169.297 77.855  88.486  1.00 172.90 ? 98  TYR A CA  1 
ATOM   185   C C   . TYR A 1 98  ? 168.362 77.198  89.510  1.00 173.08 ? 98  TYR A C   1 
ATOM   186   O O   . TYR A 1 98  ? 168.799 76.333  90.272  1.00 173.24 ? 98  TYR A O   1 
ATOM   187   C CB  . TYR A 1 98  ? 169.695 79.261  88.936  1.00 172.63 ? 98  TYR A CB  1 
ATOM   188   C CG  . TYR A 1 98  ? 170.464 79.250  90.242  1.00 173.38 ? 98  TYR A CG  1 
ATOM   189   C CD1 . TYR A 1 98  ? 171.817 78.857  90.249  1.00 172.92 ? 98  TYR A CD1 1 
ATOM   190   C CD2 . TYR A 1 98  ? 169.831 79.594  91.451  1.00 172.51 ? 98  TYR A CD2 1 
ATOM   191   C CE1 . TYR A 1 98  ? 172.545 78.842  91.456  1.00 172.88 ? 98  TYR A CE1 1 
ATOM   192   C CE2 . TYR A 1 98  ? 170.553 79.576  92.659  1.00 172.91 ? 98  TYR A CE2 1 
ATOM   193   C CZ  . TYR A 1 98  ? 171.918 79.215  92.662  1.00 173.61 ? 98  TYR A CZ  1 
ATOM   194   O OH  . TYR A 1 98  ? 172.630 79.216  93.819  1.00 171.77 ? 98  TYR A OH  1 
ATOM   195   N N   . LEU A 1 99  ? 167.074 77.556  89.512  1.00 172.99 ? 99  LEU A N   1 
ATOM   196   C CA  . LEU A 1 99  ? 166.075 76.956  90.404  1.00 173.81 ? 99  LEU A CA  1 
ATOM   197   C C   . LEU A 1 99  ? 165.941 75.448  90.156  1.00 173.47 ? 99  LEU A C   1 
ATOM   198   O O   . LEU A 1 99  ? 166.024 74.659  91.098  1.00 172.04 ? 99  LEU A O   1 
ATOM   199   C CB  . LEU A 1 99  ? 164.723 77.663  90.215  1.00 173.48 ? 99  LEU A CB  1 
ATOM   200   C CG  . LEU A 1 99  ? 164.682 79.107  90.741  1.00 173.13 ? 99  LEU A CG  1 
ATOM   201   C CD1 . LEU A 1 99  ? 163.382 79.763  90.286  1.00 172.85 ? 99  LEU A CD1 1 
ATOM   202   C CD2 . LEU A 1 99  ? 164.758 79.179  92.265  1.00 170.64 ? 99  LEU A CD2 1 
ATOM   203   N N   . ARG A 1 100 ? 165.818 75.027  88.890  1.00 175.73 ? 100 ARG A N   1 
ATOM   204   C CA  . ARG A 1 100 ? 165.733 73.605  88.514  1.00 175.75 ? 100 ARG A CA  1 
ATOM   205   C C   . ARG A 1 100 ? 167.004 72.823  88.852  1.00 175.90 ? 100 ARG A C   1 
ATOM   206   O O   . ARG A 1 100 ? 166.908 71.727  89.401  1.00 175.95 ? 100 ARG A O   1 
ATOM   207   C CB  . ARG A 1 100 ? 165.404 73.482  87.019  1.00 174.90 ? 100 ARG A CB  1 
ATOM   208   C CG  . ARG A 1 100 ? 163.940 73.835  86.723  1.00 174.09 ? 100 ARG A CG  1 
ATOM   209   C CD  . ARG A 1 100 ? 163.673 73.747  85.219  1.00 173.86 ? 100 ARG A CD  1 
ATOM   210   N NE  . ARG A 1 100 ? 162.240 73.870  84.905  1.00 175.81 ? 100 ARG A NE  1 
ATOM   211   C CZ  . ARG A 1 100 ? 161.683 73.738  83.717  1.00 175.45 ? 100 ARG A CZ  1 
ATOM   212   N NH1 . ARG A 1 100 ? 160.396 73.826  83.590  1.00 174.36 ? 100 ARG A NH1 1 
ATOM   213   N NH2 . ARG A 1 100 ? 162.380 73.523  82.641  1.00 174.77 ? 100 ARG A NH2 1 
ATOM   214   N N   . TRP A 1 101 ? 168.187 73.377  88.585  1.00 177.48 ? 101 TRP A N   1 
ATOM   215   C CA  . TRP A 1 101 ? 169.466 72.701  88.842  1.00 177.61 ? 101 TRP A CA  1 
ATOM   216   C C   . TRP A 1 101 ? 169.738 72.504  90.342  1.00 177.80 ? 101 TRP A C   1 
ATOM   217   O O   . TRP A 1 101 ? 170.217 71.449  90.752  1.00 176.21 ? 101 TRP A O   1 
ATOM   218   C CB  . TRP A 1 101 ? 170.591 73.479  88.143  1.00 177.18 ? 101 TRP A CB  1 
ATOM   219   C CG  . TRP A 1 101 ? 171.933 72.814  88.119  1.00 178.34 ? 101 TRP A CG  1 
ATOM   220   C CD1 . TRP A 1 101 ? 172.386 72.028  87.115  1.00 177.28 ? 101 TRP A CD1 1 
ATOM   221   C CD2 . TRP A 1 101 ? 172.999 72.825  89.121  1.00 179.09 ? 101 TRP A CD2 1 
ATOM   222   N NE1 . TRP A 1 101 ? 173.648 71.563  87.417  1.00 177.77 ? 101 TRP A NE1 1 
ATOM   223   C CE2 . TRP A 1 101 ? 174.076 72.018  88.644  1.00 179.18 ? 101 TRP A CE2 1 
ATOM   224   C CE3 . TRP A 1 101 ? 173.171 73.429  90.384  1.00 177.55 ? 101 TRP A CE3 1 
ATOM   225   C CZ2 . TRP A 1 101 ? 175.252 71.817  89.380  1.00 177.81 ? 101 TRP A CZ2 1 
ATOM   226   C CZ3 . TRP A 1 101 ? 174.347 73.236  91.132  1.00 176.74 ? 101 TRP A CZ3 1 
ATOM   227   C CH2 . TRP A 1 101 ? 175.388 72.432  90.634  1.00 177.01 ? 101 TRP A CH2 1 
ATOM   228   N N   . ASN A 1 102 ? 169.364 73.475  91.182  1.00 177.50 ? 102 ASN A N   1 
ATOM   229   C CA  . ASN A 1 102 ? 169.424 73.348  92.645  1.00 177.02 ? 102 ASN A CA  1 
ATOM   230   C C   . ASN A 1 102 ? 168.216 72.594  93.251  1.00 177.42 ? 102 ASN A C   1 
ATOM   231   O O   . ASN A 1 102 ? 168.266 72.211  94.418  1.00 177.32 ? 102 ASN A O   1 
ATOM   232   C CB  . ASN A 1 102 ? 169.581 74.742  93.274  1.00 177.84 ? 102 ASN A CB  1 
ATOM   233   C CG  . ASN A 1 102 ? 170.935 75.363  92.984  1.00 177.97 ? 102 ASN A CG  1 
ATOM   234   O OD1 . ASN A 1 102 ? 171.903 75.154  93.699  1.00 176.83 ? 102 ASN A OD1 1 
ATOM   235   N ND2 . ASN A 1 102 ? 171.043 76.146  91.942  1.00 177.69 ? 102 ASN A ND2 1 
ATOM   236   N N   . SER A 1 103 ? 167.141 72.369  92.488  1.00 175.44 ? 103 SER A N   1 
ATOM   237   C CA  . SER A 1 103 ? 165.831 71.840  92.925  1.00 175.40 ? 103 SER A CA  1 
ATOM   238   C C   . SER A 1 103 ? 165.085 72.719  93.953  1.00 175.70 ? 103 SER A C   1 
ATOM   239   O O   . SER A 1 103 ? 164.299 72.221  94.763  1.00 174.28 ? 103 SER A O   1 
ATOM   240   C CB  . SER A 1 103 ? 165.925 70.354  93.315  1.00 174.43 ? 103 SER A CB  1 
ATOM   241   O OG  . SER A 1 103 ? 166.576 70.159  94.558  1.00 175.43 ? 103 SER A OG  1 
ATOM   242   N N   . LYS A 1 104 ? 165.331 74.037  93.936  1.00 171.66 ? 104 LYS A N   1 
ATOM   243   C CA  . LYS A 1 104 ? 164.770 75.014  94.891  1.00 170.50 ? 104 LYS A CA  1 
ATOM   244   C C   . LYS A 1 104 ? 163.583 75.788  94.312  1.00 171.29 ? 104 LYS A C   1 
ATOM   245   O O   . LYS A 1 104 ? 163.381 75.815  93.100  1.00 170.39 ? 104 LYS A O   1 
ATOM   246   C CB  . LYS A 1 104 ? 165.873 75.964  95.384  1.00 170.25 ? 104 LYS A CB  1 
ATOM   247   C CG  . LYS A 1 104 ? 166.974 75.186  96.114  1.00 170.92 ? 104 LYS A CG  1 
ATOM   248   C CD  . LYS A 1 104 ? 167.934 76.085  96.905  1.00 170.42 ? 104 LYS A CD  1 
ATOM   249   C CE  . LYS A 1 104 ? 167.288 76.661  98.171  1.00 171.00 ? 104 LYS A CE  1 
ATOM   250   N NZ  . LYS A 1 104 ? 167.002 75.611  99.180  1.00 170.60 ? 104 LYS A NZ  1 
ATOM   251   N N   . TYR A 1 105 ? 162.823 76.448  95.188  1.00 164.08 ? 105 TYR A N   1 
ATOM   252   C CA  . TYR A 1 105 ? 161.614 77.208  94.856  1.00 162.26 ? 105 TYR A CA  1 
ATOM   253   C C   . TYR A 1 105 ? 161.680 78.654  95.374  1.00 161.39 ? 105 TYR A C   1 
ATOM   254   O O   . TYR A 1 105 ? 162.226 78.906  96.447  1.00 160.84 ? 105 TYR A O   1 
ATOM   255   C CB  . TYR A 1 105 ? 160.388 76.492  95.445  1.00 161.34 ? 105 TYR A CB  1 
ATOM   256   C CG  . TYR A 1 105 ? 160.250 75.017  95.117  1.00 162.38 ? 105 TYR A CG  1 
ATOM   257   C CD1 . TYR A 1 105 ? 159.998 74.604  93.796  1.00 162.22 ? 105 TYR A CD1 1 
ATOM   258   C CD2 . TYR A 1 105 ? 160.343 74.057  96.143  1.00 161.17 ? 105 TYR A CD2 1 
ATOM   259   C CE1 . TYR A 1 105 ? 159.820 73.238  93.506  1.00 161.96 ? 105 TYR A CE1 1 
ATOM   260   C CE2 . TYR A 1 105 ? 160.180 72.690  95.852  1.00 161.84 ? 105 TYR A CE2 1 
ATOM   261   C CZ  . TYR A 1 105 ? 159.908 72.278  94.533  1.00 162.09 ? 105 TYR A CZ  1 
ATOM   262   O OH  . TYR A 1 105 ? 159.713 70.968  94.245  1.00 160.33 ? 105 TYR A OH  1 
ATOM   263   N N   . LEU A 1 106 ? 161.044 79.599  94.675  1.00 150.03 ? 106 LEU A N   1 
ATOM   264   C CA  . LEU A 1 106 ? 160.999 81.022  95.062  1.00 149.32 ? 106 LEU A CA  1 
ATOM   265   C C   . LEU A 1 106 ? 160.273 81.300  96.395  1.00 151.31 ? 106 LEU A C   1 
ATOM   266   O O   . LEU A 1 106 ? 160.381 82.400  96.934  1.00 150.36 ? 106 LEU A O   1 
ATOM   267   C CB  . LEU A 1 106 ? 160.357 81.840  93.925  1.00 149.54 ? 106 LEU A CB  1 
ATOM   268   C CG  . LEU A 1 106 ? 161.182 81.913  92.632  1.00 150.79 ? 106 LEU A CG  1 
ATOM   269   C CD1 . LEU A 1 106 ? 160.408 82.700  91.579  1.00 149.77 ? 106 LEU A CD1 1 
ATOM   270   C CD2 . LEU A 1 106 ? 162.518 82.609  92.866  1.00 152.39 ? 106 LEU A CD2 1 
ATOM   271   N N   . THR A 1 107 ? 159.542 80.324  96.938  1.00 156.75 ? 107 THR A N   1 
ATOM   272   C CA  . THR A 1 107 ? 158.887 80.398  98.261  1.00 155.38 ? 107 THR A CA  1 
ATOM   273   C C   . THR A 1 107 ? 159.633 79.644  99.366  1.00 155.20 ? 107 THR A C   1 
ATOM   274   O O   . THR A 1 107 ? 159.154 79.598  100.500 1.00 155.29 ? 107 THR A O   1 
ATOM   275   C CB  . THR A 1 107 ? 157.417 79.952  98.195  1.00 154.37 ? 107 THR A CB  1 
ATOM   276   O OG1 . THR A 1 107 ? 157.274 78.630  97.736  1.00 154.90 ? 107 THR A OG1 1 
ATOM   277   C CG2 . THR A 1 107 ? 156.629 80.836  97.246  1.00 154.02 ? 107 THR A CG2 1 
ATOM   278   N N   . ASP A 1 108 ? 160.810 79.070  99.090  1.00 155.88 ? 108 ASP A N   1 
ATOM   279   C CA  . ASP A 1 108 ? 161.694 78.533  100.131 1.00 156.33 ? 108 ASP A CA  1 
ATOM   280   C C   . ASP A 1 108 ? 162.414 79.665  100.891 1.00 156.00 ? 108 ASP A C   1 
ATOM   281   O O   . ASP A 1 108 ? 162.648 80.742  100.342 1.00 155.96 ? 108 ASP A O   1 
ATOM   282   C CB  . ASP A 1 108 ? 162.703 77.553  99.512  1.00 156.90 ? 108 ASP A CB  1 
ATOM   283   C CG  . ASP A 1 108 ? 163.459 76.734  100.566 1.00 157.28 ? 108 ASP A CG  1 
ATOM   284   O OD1 . ASP A 1 108 ? 162.951 76.586  101.697 1.00 156.00 ? 108 ASP A OD1 1 
ATOM   285   O OD2 . ASP A 1 108 ? 164.571 76.252  100.264 1.00 157.10 ? 108 ASP A OD2 1 
ATOM   286   N N   . SER A 1 109 ? 162.820 79.426  102.142 1.00 151.54 ? 109 SER A N   1 
ATOM   287   C CA  . SER A 1 109 ? 163.403 80.442  103.043 1.00 152.67 ? 109 SER A CA  1 
ATOM   288   C C   . SER A 1 109 ? 164.573 81.222  102.422 1.00 153.60 ? 109 SER A C   1 
ATOM   289   O O   . SER A 1 109 ? 164.670 82.439  102.591 1.00 152.91 ? 109 SER A O   1 
ATOM   290   C CB  . SER A 1 109 ? 163.855 79.756  104.338 1.00 151.35 ? 109 SER A CB  1 
ATOM   291   O OG  . SER A 1 109 ? 164.431 80.680  105.238 1.00 150.29 ? 109 SER A OG  1 
ATOM   292   N N   . ALA A 1 110 ? 165.397 80.555  101.610 1.00 152.06 ? 110 ALA A N   1 
ATOM   293   C CA  . ALA A 1 110 ? 166.530 81.150  100.902 1.00 150.46 ? 110 ALA A CA  1 
ATOM   294   C C   . ALA A 1 110 ? 166.172 82.355  100.005 1.00 151.80 ? 110 ALA A C   1 
ATOM   295   O O   . ALA A 1 110 ? 167.048 83.170  99.737  1.00 152.76 ? 110 ALA A O   1 
ATOM   296   C CB  . ALA A 1 110 ? 167.191 80.041  100.077 1.00 149.74 ? 110 ALA A CB  1 
ATOM   297   N N   . TYR A 1 111 ? 164.914 82.503  99.574  1.00 152.16 ? 111 TYR A N   1 
ATOM   298   C CA  . TYR A 1 111 ? 164.421 83.605  98.735  1.00 151.30 ? 111 TYR A CA  1 
ATOM   299   C C   . TYR A 1 111 ? 163.510 84.591  99.491  1.00 150.40 ? 111 TYR A C   1 
ATOM   300   O O   . TYR A 1 111 ? 162.676 85.260  98.887  1.00 150.07 ? 111 TYR A O   1 
ATOM   301   C CB  . TYR A 1 111 ? 163.776 83.027  97.466  1.00 152.43 ? 111 TYR A CB  1 
ATOM   302   C CG  . TYR A 1 111 ? 164.776 82.474  96.471  1.00 151.55 ? 111 TYR A CG  1 
ATOM   303   C CD1 . TYR A 1 111 ? 165.348 83.338  95.519  1.00 150.52 ? 111 TYR A CD1 1 
ATOM   304   C CD2 . TYR A 1 111 ? 165.139 81.117  96.495  1.00 151.87 ? 111 TYR A CD2 1 
ATOM   305   C CE1 . TYR A 1 111 ? 166.284 82.849  94.591  1.00 152.32 ? 111 TYR A CE1 1 
ATOM   306   C CE2 . TYR A 1 111 ? 166.090 80.630  95.581  1.00 151.83 ? 111 TYR A CE2 1 
ATOM   307   C CZ  . TYR A 1 111 ? 166.665 81.495  94.630  1.00 153.69 ? 111 TYR A CZ  1 
ATOM   308   O OH  . TYR A 1 111 ? 167.600 81.024  93.764  1.00 155.97 ? 111 TYR A OH  1 
ATOM   309   N N   . THR A 1 112 ? 163.660 84.716  100.813 1.00 144.04 ? 112 THR A N   1 
ATOM   310   C CA  . THR A 1 112 ? 162.829 85.593  101.656 1.00 145.72 ? 112 THR A CA  1 
ATOM   311   C C   . THR A 1 112 ? 163.640 86.661  102.396 1.00 145.60 ? 112 THR A C   1 
ATOM   312   O O   . THR A 1 112 ? 164.809 86.454  102.730 1.00 147.17 ? 112 THR A O   1 
ATOM   313   C CB  . THR A 1 112 ? 161.970 84.789  102.641 1.00 146.74 ? 112 THR A CB  1 
ATOM   314   O OG1 . THR A 1 112 ? 162.755 84.117  103.595 1.00 145.16 ? 112 THR A OG1 1 
ATOM   315   C CG2 . THR A 1 112 ? 161.093 83.756  101.942 1.00 145.06 ? 112 THR A CG2 1 
ATOM   316   N N   . GLU A 1 113 ? 163.047 87.839  102.624 1.00 141.01 ? 113 GLU A N   1 
ATOM   317   C CA  . GLU A 1 113 ? 163.678 88.922  103.390 1.00 141.78 ? 113 GLU A CA  1 
ATOM   318   C C   . GLU A 1 113 ? 163.848 88.552  104.878 1.00 142.07 ? 113 GLU A C   1 
ATOM   319   O O   . GLU A 1 113 ? 163.104 87.737  105.426 1.00 140.63 ? 113 GLU A O   1 
ATOM   320   C CB  . GLU A 1 113 ? 162.910 90.247  103.208 1.00 141.77 ? 113 GLU A CB  1 
ATOM   321   C CG  . GLU A 1 113 ? 163.830 91.461  103.223 1.00 140.76 ? 113 GLU A CG  1 
ATOM   322   C CD  . GLU A 1 113 ? 163.188 92.739  102.671 1.00 142.75 ? 113 GLU A CD  1 
ATOM   323   O OE1 . GLU A 1 113 ? 162.259 93.281  103.296 1.00 142.30 ? 113 GLU A OE1 1 
ATOM   324   O OE2 . GLU A 1 113 ? 163.620 93.229  101.612 1.00 143.85 ? 113 GLU A OE2 1 
ATOM   325   N N   . GLY A 1 114 ? 164.848 89.130  105.548 1.00 142.83 ? 114 GLY A N   1 
ATOM   326   C CA  . GLY A 1 114 ? 165.219 88.769  106.919 1.00 141.81 ? 114 GLY A CA  1 
ATOM   327   C C   . GLY A 1 114 ? 164.163 89.106  107.976 1.00 143.13 ? 114 GLY A C   1 
ATOM   328   O O   . GLY A 1 114 ? 163.479 90.127  107.890 1.00 142.31 ? 114 GLY A O   1 
ATOM   329   N N   . SER A 1 115 ? 164.057 88.261  109.006 1.00 140.99 ? 115 SER A N   1 
ATOM   330   C CA  . SER A 1 115 ? 163.125 88.393  110.145 1.00 139.73 ? 115 SER A CA  1 
ATOM   331   C C   . SER A 1 115 ? 161.634 88.425  109.766 1.00 139.27 ? 115 SER A C   1 
ATOM   332   O O   . SER A 1 115 ? 160.802 88.917  110.525 1.00 137.08 ? 115 SER A O   1 
ATOM   333   C CB  . SER A 1 115 ? 163.513 89.564  111.062 1.00 138.79 ? 115 SER A CB  1 
ATOM   334   O OG  . SER A 1 115 ? 164.856 89.432  111.491 1.00 138.05 ? 115 SER A OG  1 
ATOM   335   N N   . THR A 1 116 ? 161.279 87.892  108.596 1.00 138.40 ? 116 THR A N   1 
ATOM   336   C CA  . THR A 1 116 ? 159.904 87.791  108.077 1.00 137.46 ? 116 THR A CA  1 
ATOM   337   C C   . THR A 1 116 ? 159.800 86.636  107.056 1.00 134.93 ? 116 THR A C   1 
ATOM   338   O O   . THR A 1 116 ? 160.694 85.796  106.985 1.00 136.12 ? 116 THR A O   1 
ATOM   339   C CB  . THR A 1 116 ? 159.457 89.162  107.525 1.00 134.07 ? 116 THR A CB  1 
ATOM   340   O OG1 . THR A 1 116 ? 158.103 89.127  107.158 1.00 131.58 ? 116 THR A OG1 1 
ATOM   341   C CG2 . THR A 1 116 ? 160.245 89.644  106.309 1.00 132.40 ? 116 THR A CG2 1 
ATOM   342   N N   . GLY A 1 117 ? 158.722 86.559  106.271 1.00 121.64 ? 117 GLY A N   1 
ATOM   343   C CA  . GLY A 1 117 ? 158.542 85.591  105.174 1.00 124.46 ? 117 GLY A CA  1 
ATOM   344   C C   . GLY A 1 117 ? 158.459 86.229  103.781 1.00 124.93 ? 117 GLY A C   1 
ATOM   345   O O   . GLY A 1 117 ? 158.162 85.554  102.801 1.00 125.66 ? 117 GLY A O   1 
ATOM   346   N N   . LYS A 1 118 ? 158.678 87.543  103.702 1.00 121.52 ? 118 LYS A N   1 
ATOM   347   C CA  . LYS A 1 118 ? 158.444 88.409  102.541 1.00 121.91 ? 118 LYS A CA  1 
ATOM   348   C C   . LYS A 1 118 ? 159.208 87.943  101.302 1.00 120.73 ? 118 LYS A C   1 
ATOM   349   O O   . LYS A 1 118 ? 160.430 87.835  101.343 1.00 125.48 ? 118 LYS A O   1 
ATOM   350   C CB  . LYS A 1 118 ? 158.844 89.813  102.994 1.00 122.47 ? 118 LYS A CB  1 
ATOM   351   C CG  . LYS A 1 118 ? 158.656 90.950  101.988 1.00 121.32 ? 118 LYS A CG  1 
ATOM   352   C CD  . LYS A 1 118 ? 159.028 92.235  102.736 1.00 123.93 ? 118 LYS A CD  1 
ATOM   353   C CE  . LYS A 1 118 ? 159.173 93.460  101.841 1.00 123.38 ? 118 LYS A CE  1 
ATOM   354   N NZ  . LYS A 1 118 ? 159.859 94.547  102.581 1.00 125.35 ? 118 LYS A NZ  1 
ATOM   355   N N   . THR A 1 119 ? 158.494 87.645  100.221 1.00 126.50 ? 119 THR A N   1 
ATOM   356   C CA  . THR A 1 119 ? 159.037 87.022  99.001  1.00 129.18 ? 119 THR A CA  1 
ATOM   357   C C   . THR A 1 119 ? 159.430 88.036  97.930  1.00 127.83 ? 119 THR A C   1 
ATOM   358   O O   . THR A 1 119 ? 159.075 89.215  97.992  1.00 126.85 ? 119 THR A O   1 
ATOM   359   C CB  . THR A 1 119 ? 158.040 86.017  98.398  1.00 131.26 ? 119 THR A CB  1 
ATOM   360   O OG1 . THR A 1 119 ? 156.899 86.689  97.916  1.00 130.67 ? 119 THR A OG1 1 
ATOM   361   C CG2 . THR A 1 119 ? 157.580 84.944  99.378  1.00 129.15 ? 119 THR A CG2 1 
ATOM   362   N N   . CYS A 1 120 ? 160.096 87.561  96.882  1.00 131.76 ? 120 CYS A N   1 
ATOM   363   C CA  . CYS A 1 120 ? 160.389 88.326  95.666  1.00 133.51 ? 120 CYS A CA  1 
ATOM   364   C C   . CYS A 1 120 ? 159.145 88.927  94.997  1.00 135.32 ? 120 CYS A C   1 
ATOM   365   O O   . CYS A 1 120 ? 159.219 90.033  94.471  1.00 134.36 ? 120 CYS A O   1 
ATOM   366   C CB  . CYS A 1 120 ? 161.132 87.406  94.684  1.00 134.14 ? 120 CYS A CB  1 
ATOM   367   S SG  . CYS A 1 120 ? 160.221 85.858  94.441  1.00 135.11 ? 120 CYS A SG  1 
ATOM   368   N N   . LEU A 1 121 ? 157.983 88.267  95.051  1.00 128.91 ? 121 LEU A N   1 
ATOM   369   C CA  . LEU A 1 121 ? 156.738 88.827  94.520  1.00 127.17 ? 121 LEU A CA  1 
ATOM   370   C C   . LEU A 1 121 ? 156.270 90.039  95.339  1.00 127.63 ? 121 LEU A C   1 
ATOM   371   O O   . LEU A 1 121 ? 155.842 91.035  94.766  1.00 130.87 ? 121 LEU A O   1 
ATOM   372   C CB  . LEU A 1 121 ? 155.672 87.724  94.439  1.00 125.63 ? 121 LEU A CB  1 
ATOM   373   C CG  . LEU A 1 121 ? 154.330 88.183  93.840  1.00 125.39 ? 121 LEU A CG  1 
ATOM   374   C CD1 . LEU A 1 121 ? 154.441 88.484  92.350  1.00 126.27 ? 121 LEU A CD1 1 
ATOM   375   C CD2 . LEU A 1 121 ? 153.279 87.095  94.024  1.00 125.94 ? 121 LEU A CD2 1 
ATOM   376   N N   . MET A 1 122 ? 156.393 90.010  96.663  1.00 114.28 ? 122 MET A N   1 
ATOM   377   C CA  . MET A 1 122 ? 156.093 91.189  97.476  1.00 114.83 ? 122 MET A CA  1 
ATOM   378   C C   . MET A 1 122 ? 157.060 92.340  97.150  1.00 117.83 ? 122 MET A C   1 
ATOM   379   O O   . MET A 1 122 ? 156.624 93.469  96.940  1.00 114.54 ? 122 MET A O   1 
ATOM   380   C CB  . MET A 1 122 ? 156.116 90.800  98.957  1.00 116.99 ? 122 MET A CB  1 
ATOM   381   C CG  . MET A 1 122 ? 155.077 89.719  99.253  1.00 112.92 ? 122 MET A CG  1 
ATOM   382   S SD  . MET A 1 122 ? 155.033 89.198  100.974 1.00 113.27 ? 122 MET A SD  1 
ATOM   383   C CE  . MET A 1 122 ? 154.374 87.534  100.760 1.00 113.37 ? 122 MET A CE  1 
ATOM   384   N N   . LYS A 1 123 ? 158.361 92.052  96.996  1.00 129.75 ? 123 LYS A N   1 
ATOM   385   C CA  . LYS A 1 123 ? 159.389 93.009  96.550  1.00 128.03 ? 123 LYS A CA  1 
ATOM   386   C C   . LYS A 1 123 ? 159.072 93.620  95.174  1.00 128.17 ? 123 LYS A C   1 
ATOM   387   O O   . LYS A 1 123 ? 159.277 94.813  94.977  1.00 128.74 ? 123 LYS A O   1 
ATOM   388   C CB  . LYS A 1 123 ? 160.756 92.298  96.560  1.00 127.22 ? 123 LYS A CB  1 
ATOM   389   C CG  . LYS A 1 123 ? 161.966 93.234  96.609  1.00 130.13 ? 123 LYS A CG  1 
ATOM   390   C CD  . LYS A 1 123 ? 162.157 93.890  97.976  1.00 129.01 ? 123 LYS A CD  1 
ATOM   391   C CE  . LYS A 1 123 ? 163.451 94.696  98.008  1.00 129.46 ? 123 LYS A CE  1 
ATOM   392   N NZ  . LYS A 1 123 ? 163.687 95.300  99.335  1.00 128.58 ? 123 LYS A NZ  1 
ATOM   393   N N   . ALA A 1 124 ? 158.513 92.828  94.253  1.00 121.64 ? 124 ALA A N   1 
ATOM   394   C CA  . ALA A 1 124 ? 158.049 93.276  92.941  1.00 120.87 ? 124 ALA A CA  1 
ATOM   395   C C   . ALA A 1 124 ? 156.818 94.192  93.030  1.00 121.28 ? 124 ALA A C   1 
ATOM   396   O O   . ALA A 1 124 ? 156.807 95.270  92.438  1.00 121.76 ? 124 ALA A O   1 
ATOM   397   C CB  . ALA A 1 124 ? 157.748 92.044  92.078  1.00 118.81 ? 124 ALA A CB  1 
ATOM   398   N N   . VAL A 1 125 ? 155.790 93.796  93.786  1.00 117.51 ? 125 VAL A N   1 
ATOM   399   C CA  . VAL A 1 125 ? 154.533 94.556  93.927  1.00 115.15 ? 125 VAL A CA  1 
ATOM   400   C C   . VAL A 1 125 ? 154.705 95.840  94.757  1.00 114.04 ? 125 VAL A C   1 
ATOM   401   O O   . VAL A 1 125 ? 153.988 96.805  94.535  1.00 112.31 ? 125 VAL A O   1 
ATOM   402   C CB  . VAL A 1 125 ? 153.418 93.651  94.491  1.00 112.88 ? 125 VAL A CB  1 
ATOM   403   C CG1 . VAL A 1 125 ? 152.089 94.384  94.670  1.00 112.10 ? 125 VAL A CG1 1 
ATOM   404   C CG2 . VAL A 1 125 ? 153.105 92.489  93.541  1.00 113.46 ? 125 VAL A CG2 1 
ATOM   405   N N   . LEU A 1 126 ? 155.690 95.926  95.655  1.00 110.74 ? 126 LEU A N   1 
ATOM   406   C CA  . LEU A 1 126 ? 156.058 97.184  96.322  1.00 109.87 ? 126 LEU A CA  1 
ATOM   407   C C   . LEU A 1 126 ? 156.677 98.239  95.377  1.00 110.14 ? 126 LEU A C   1 
ATOM   408   O O   . LEU A 1 126 ? 156.767 99.407  95.743  1.00 107.98 ? 126 LEU A O   1 
ATOM   409   C CB  . LEU A 1 126 ? 157.016 96.863  97.486  1.00 105.33 ? 126 LEU A CB  1 
ATOM   410   C CG  . LEU A 1 126 ? 156.325 96.206  98.688  1.00 106.27 ? 126 LEU A CG  1 
ATOM   411   C CD1 . LEU A 1 126 ? 157.333 95.520  99.600  1.00 107.53 ? 126 LEU A CD1 1 
ATOM   412   C CD2 . LEU A 1 126 ? 155.567 97.234  99.521  1.00 107.33 ? 126 LEU A CD2 1 
ATOM   413   N N   . ASN A 1 127 ? 157.099 97.850  94.170  1.00 124.50 ? 127 ASN A N   1 
ATOM   414   C CA  . ASN A 1 127 ? 157.849 98.672  93.214  1.00 123.54 ? 127 ASN A CA  1 
ATOM   415   C C   . ASN A 1 127 ? 157.114 98.827  91.866  1.00 125.55 ? 127 ASN A C   1 
ATOM   416   O O   . ASN A 1 127 ? 157.713 98.729  90.799  1.00 123.84 ? 127 ASN A O   1 
ATOM   417   C CB  . ASN A 1 127 ? 159.278 98.112  93.099  1.00 123.17 ? 127 ASN A CB  1 
ATOM   418   C CG  . ASN A 1 127 ? 160.095 98.400  94.343  1.00 125.85 ? 127 ASN A CG  1 
ATOM   419   O OD1 . ASN A 1 127 ? 160.509 99.523  94.586  1.00 124.45 ? 127 ASN A OD1 1 
ATOM   420   N ND2 . ASN A 1 127 ? 160.361 97.424  95.171  1.00 124.09 ? 127 ASN A ND2 1 
ATOM   421   N N   . LEU A 1 128 ? 155.799 99.080  91.883  1.00 132.52 ? 128 LEU A N   1 
ATOM   422   C CA  . LEU A 1 128 ? 155.026 99.377  90.666  1.00 132.24 ? 128 LEU A CA  1 
ATOM   423   C C   . LEU A 1 128 ? 155.459 100.711 90.036  1.00 131.85 ? 128 LEU A C   1 
ATOM   424   O O   . LEU A 1 128 ? 155.708 101.689 90.739  1.00 128.96 ? 128 LEU A O   1 
ATOM   425   C CB  . LEU A 1 128 ? 153.510 99.414  90.940  1.00 130.45 ? 128 LEU A CB  1 
ATOM   426   C CG  . LEU A 1 128 ? 152.907 98.192  91.643  1.00 130.22 ? 128 LEU A CG  1 
ATOM   427   C CD1 . LEU A 1 128 ? 151.393 98.316  91.694  1.00 130.25 ? 128 LEU A CD1 1 
ATOM   428   C CD2 . LEU A 1 128 ? 153.242 96.873  90.957  1.00 129.16 ? 128 LEU A CD2 1 
ATOM   429   N N   . GLN A 1 129 ? 155.505 100.766 88.708  1.00 141.99 ? 129 GLN A N   1 
ATOM   430   C CA  . GLN A 1 129 ? 155.856 101.948 87.917  1.00 141.88 ? 129 GLN A CA  1 
ATOM   431   C C   . GLN A 1 129 ? 154.647 102.340 87.062  1.00 140.30 ? 129 GLN A C   1 
ATOM   432   O O   . GLN A 1 129 ? 154.150 101.535 86.277  1.00 138.60 ? 129 GLN A O   1 
ATOM   433   C CB  . GLN A 1 129 ? 157.096 101.632 87.061  1.00 139.52 ? 129 GLN A CB  1 
ATOM   434   C CG  . GLN A 1 129 ? 158.339 101.325 87.920  1.00 138.05 ? 129 GLN A CG  1 
ATOM   435   C CD  . GLN A 1 129 ? 159.511 100.735 87.137  1.00 138.72 ? 129 GLN A CD  1 
ATOM   436   O OE1 . GLN A 1 129 ? 159.469 100.506 85.938  1.00 139.49 ? 129 GLN A OE1 1 
ATOM   437   N NE2 . GLN A 1 129 ? 160.613 100.456 87.794  1.00 139.78 ? 129 GLN A NE2 1 
ATOM   438   N N   . ASP A 1 130 ? 154.120 103.555 87.234  1.00 137.80 ? 130 ASP A N   1 
ATOM   439   C CA  . ASP A 1 130 ? 152.896 103.999 86.551  1.00 138.01 ? 130 ASP A CA  1 
ATOM   440   C C   . ASP A 1 130 ? 151.692 103.042 86.713  1.00 138.26 ? 130 ASP A C   1 
ATOM   441   O O   . ASP A 1 130 ? 150.848 102.926 85.829  1.00 137.58 ? 130 ASP A O   1 
ATOM   442   C CB  . ASP A 1 130 ? 153.211 104.299 85.084  1.00 136.25 ? 130 ASP A CB  1 
ATOM   443   N N   . GLY A 1 131 ? 151.618 102.336 87.849  1.00 135.36 ? 131 GLY A N   1 
ATOM   444   C CA  . GLY A 1 131 ? 150.551 101.387 88.191  1.00 135.09 ? 131 GLY A CA  1 
ATOM   445   C C   . GLY A 1 131 ? 150.821 99.903  87.907  1.00 135.03 ? 131 GLY A C   1 
ATOM   446   O O   . GLY A 1 131 ? 149.979 99.085  88.273  1.00 135.96 ? 131 GLY A O   1 
ATOM   447   N N   . VAL A 1 132 ? 151.955 99.516  87.303  1.00 137.66 ? 132 VAL A N   1 
ATOM   448   C CA  . VAL A 1 132 ? 152.291 98.100  86.998  1.00 139.14 ? 132 VAL A CA  1 
ATOM   449   C C   . VAL A 1 132 ? 153.800 97.805  87.095  1.00 138.94 ? 132 VAL A C   1 
ATOM   450   O O   . VAL A 1 132 ? 154.622 98.694  86.914  1.00 135.51 ? 132 VAL A O   1 
ATOM   451   C CB  . VAL A 1 132 ? 151.710 97.715  85.620  1.00 137.58 ? 132 VAL A CB  1 
ATOM   452   C CG1 . VAL A 1 132 ? 152.412 98.400  84.446  1.00 136.89 ? 132 VAL A CG1 1 
ATOM   453   C CG2 . VAL A 1 132 ? 151.730 96.205  85.374  1.00 134.85 ? 132 VAL A CG2 1 
ATOM   454   N N   . ASN A 1 133 ? 154.199 96.564  87.394  1.00 140.41 ? 133 ASN A N   1 
ATOM   455   C CA  . ASN A 1 133 ? 155.592 96.103  87.286  1.00 139.62 ? 133 ASN A CA  1 
ATOM   456   C C   . ASN A 1 133 ? 155.689 94.981  86.239  1.00 140.53 ? 133 ASN A C   1 
ATOM   457   O O   . ASN A 1 133 ? 155.083 93.921  86.397  1.00 139.82 ? 133 ASN A O   1 
ATOM   458   C CB  . ASN A 1 133 ? 156.102 95.683  88.679  1.00 139.92 ? 133 ASN A CB  1 
ATOM   459   C CG  . ASN A 1 133 ? 157.554 95.225  88.711  1.00 140.80 ? 133 ASN A CG  1 
ATOM   460   O OD1 . ASN A 1 133 ? 158.138 94.845  87.709  1.00 139.21 ? 133 ASN A OD1 1 
ATOM   461   N ND2 . ASN A 1 133 ? 158.179 95.236  89.862  1.00 141.10 ? 133 ASN A ND2 1 
ATOM   462   N N   . ALA A 1 134 ? 156.480 95.187  85.185  1.00 146.12 ? 134 ALA A N   1 
ATOM   463   C CA  . ALA A 1 134 ? 156.619 94.239  84.079  1.00 145.08 ? 134 ALA A CA  1 
ATOM   464   C C   . ALA A 1 134 ? 157.249 92.885  84.472  1.00 146.79 ? 134 ALA A C   1 
ATOM   465   O O   . ALA A 1 134 ? 157.116 91.917  83.726  1.00 147.41 ? 134 ALA A O   1 
ATOM   466   C CB  . ALA A 1 134 ? 157.424 94.927  82.970  1.00 145.31 ? 134 ALA A CB  1 
ATOM   467   N N   . CYS A 1 135 ? 157.913 92.786  85.629  1.00 147.40 ? 135 CYS A N   1 
ATOM   468   C CA  . CYS A 1 135 ? 158.510 91.539  86.110  1.00 147.28 ? 135 CYS A CA  1 
ATOM   469   C C   . CYS A 1 135 ? 157.489 90.531  86.654  1.00 147.73 ? 135 CYS A C   1 
ATOM   470   O O   . CYS A 1 135 ? 157.804 89.347  86.707  1.00 146.85 ? 135 CYS A O   1 
ATOM   471   C CB  . CYS A 1 135 ? 159.549 91.840  87.198  1.00 148.22 ? 135 CYS A CB  1 
ATOM   472   S SG  . CYS A 1 135 ? 160.802 92.987  86.580  1.00 153.08 ? 135 CYS A SG  1 
ATOM   473   N N   . ILE A 1 136 ? 156.290 90.951  87.074  1.00 143.94 ? 136 ILE A N   1 
ATOM   474   C CA  . ILE A 1 136 ? 155.347 90.062  87.781  1.00 142.28 ? 136 ILE A CA  1 
ATOM   475   C C   . ILE A 1 136 ? 154.895 88.897  86.892  1.00 141.35 ? 136 ILE A C   1 
ATOM   476   O O   . ILE A 1 136 ? 154.988 87.746  87.302  1.00 142.51 ? 136 ILE A O   1 
ATOM   477   C CB  . ILE A 1 136 ? 154.147 90.854  88.346  1.00 142.23 ? 136 ILE A CB  1 
ATOM   478   C CG1 . ILE A 1 136 ? 154.612 91.825  89.451  1.00 141.43 ? 136 ILE A CG1 1 
ATOM   479   C CG2 . ILE A 1 136 ? 153.078 89.902  88.911  1.00 143.53 ? 136 ILE A CG2 1 
ATOM   480   C CD1 . ILE A 1 136 ? 153.566 92.891  89.778  1.00 138.36 ? 136 ILE A CD1 1 
ATOM   481   N N   . MET A 1 137 ? 154.459 89.166  85.658  1.00 146.40 ? 137 MET A N   1 
ATOM   482   C CA  . MET A 1 137 ? 154.019 88.120  84.730  1.00 147.62 ? 137 MET A CA  1 
ATOM   483   C C   . MET A 1 137 ? 155.112 87.050  84.468  1.00 147.80 ? 137 MET A C   1 
ATOM   484   O O   . MET A 1 137 ? 154.839 85.872  84.698  1.00 146.53 ? 137 MET A O   1 
ATOM   485   C CB  . MET A 1 137 ? 153.451 88.770  83.458  1.00 145.69 ? 137 MET A CB  1 
ATOM   486   C CG  . MET A 1 137 ? 152.854 87.786  82.447  1.00 146.93 ? 137 MET A CG  1 
ATOM   487   S SD  . MET A 1 137 ? 151.230 87.101  82.883  1.00 148.85 ? 137 MET A SD  1 
ATOM   488   C CE  . MET A 1 137 ? 151.700 85.496  83.565  1.00 145.66 ? 137 MET A CE  1 
ATOM   489   N N   . PRO A 1 138 ? 156.358 87.390  84.075  1.00 149.59 ? 138 PRO A N   1 
ATOM   490   C CA  . PRO A 1 138 ? 157.410 86.388  83.935  1.00 148.21 ? 138 PRO A CA  1 
ATOM   491   C C   . PRO A 1 138 ? 157.847 85.769  85.272  1.00 148.44 ? 138 PRO A C   1 
ATOM   492   O O   . PRO A 1 138 ? 158.099 84.572  85.294  1.00 149.82 ? 138 PRO A O   1 
ATOM   493   C CB  . PRO A 1 138 ? 158.561 87.073  83.196  1.00 147.27 ? 138 PRO A CB  1 
ATOM   494   C CG  . PRO A 1 138 ? 158.337 88.557  83.449  1.00 148.03 ? 138 PRO A CG  1 
ATOM   495   C CD  . PRO A 1 138 ? 156.822 88.674  83.573  1.00 148.93 ? 138 PRO A CD  1 
ATOM   496   N N   . LEU A 1 139 ? 157.881 86.498  86.393  1.00 142.98 ? 139 LEU A N   1 
ATOM   497   C CA  . LEU A 1 139 ? 158.206 85.913  87.705  1.00 143.79 ? 139 LEU A CA  1 
ATOM   498   C C   . LEU A 1 139 ? 157.197 84.820  88.105  1.00 145.49 ? 139 LEU A C   1 
ATOM   499   O O   . LEU A 1 139 ? 157.580 83.749  88.577  1.00 144.35 ? 139 LEU A O   1 
ATOM   500   C CB  . LEU A 1 139 ? 158.265 87.042  88.751  1.00 145.17 ? 139 LEU A CB  1 
ATOM   501   C CG  . LEU A 1 139 ? 158.676 86.599  90.162  1.00 144.61 ? 139 LEU A CG  1 
ATOM   502   C CD1 . LEU A 1 139 ? 160.158 86.236  90.222  1.00 145.06 ? 139 LEU A CD1 1 
ATOM   503   C CD2 . LEU A 1 139 ? 158.419 87.733  91.150  1.00 143.86 ? 139 LEU A CD2 1 
ATOM   504   N N   . LEU A 1 140 ? 155.906 85.056  87.862  1.00 144.75 ? 140 LEU A N   1 
ATOM   505   C CA  . LEU A 1 140 ? 154.857 84.064  88.078  1.00 143.51 ? 140 LEU A CA  1 
ATOM   506   C C   . LEU A 1 140 ? 154.954 82.886  87.101  1.00 142.89 ? 140 LEU A C   1 
ATOM   507   O O   . LEU A 1 140 ? 154.797 81.744  87.524  1.00 141.53 ? 140 LEU A O   1 
ATOM   508   C CB  . LEU A 1 140 ? 153.481 84.750  88.025  1.00 142.77 ? 140 LEU A CB  1 
ATOM   509   C CG  . LEU A 1 140 ? 153.220 85.715  89.194  1.00 141.61 ? 140 LEU A CG  1 
ATOM   510   C CD1 . LEU A 1 140 ? 151.833 86.337  89.059  1.00 140.75 ? 140 LEU A CD1 1 
ATOM   511   C CD2 . LEU A 1 140 ? 153.294 85.001  90.538  1.00 140.49 ? 140 LEU A CD2 1 
ATOM   512   N N   . GLN A 1 141 ? 155.349 83.136  85.860  1.00 150.71 ? 141 GLN A N   1 
ATOM   513   C CA  . GLN A 1 141 ? 155.572 81.954  84.993  1.00 150.64 ? 141 GLN A CA  1 
ATOM   514   C C   . GLN A 1 141 ? 156.746 81.166  85.582  1.00 149.63 ? 141 GLN A C   1 
ATOM   515   O O   . GLN A 1 141 ? 156.595 79.948  85.775  1.00 148.30 ? 141 GLN A O   1 
ATOM   516   C CB  . GLN A 1 141 ? 155.857 82.352  83.549  1.00 149.54 ? 141 GLN A CB  1 
ATOM   517   C CG  . GLN A 1 141 ? 155.735 81.179  82.588  1.00 149.72 ? 141 GLN A CG  1 
ATOM   518   C CD  . GLN A 1 141 ? 154.629 80.238  82.999  1.00 150.41 ? 141 GLN A CD  1 
ATOM   519   O OE1 . GLN A 1 141 ? 153.457 80.465  82.709  1.00 149.60 ? 141 GLN A OE1 1 
ATOM   520   N NE2 . GLN A 1 141 ? 154.994 79.167  83.683  1.00 150.90 ? 141 GLN A NE2 1 
ATOM   521   N N   . ILE A 1 142 ? 157.858 81.843  85.881  1.00 153.00 ? 142 ILE A N   1 
ATOM   522   C CA  . ILE A 1 142 ? 159.056 81.161  86.391  1.00 152.98 ? 142 ILE A CA  1 
ATOM   523   C C   . ILE A 1 142 ? 158.713 80.274  87.599  1.00 154.53 ? 142 ILE A C   1 
ATOM   524   O O   . ILE A 1 142 ? 159.148 79.127  87.651  1.00 153.98 ? 142 ILE A O   1 
ATOM   525   C CB  . ILE A 1 142 ? 160.163 82.193  86.701  1.00 152.92 ? 142 ILE A CB  1 
ATOM   526   C CG1 . ILE A 1 142 ? 160.712 82.777  85.380  1.00 152.57 ? 142 ILE A CG1 1 
ATOM   527   C CG2 . ILE A 1 142 ? 161.308 81.569  87.516  1.00 153.69 ? 142 ILE A CG2 1 
ATOM   528   C CD1 . ILE A 1 142 ? 161.465 84.102  85.530  1.00 153.33 ? 142 ILE A CD1 1 
ATOM   529   N N   . ASP A 1 143 ? 157.885 80.740  88.537  1.00 154.73 ? 143 ASP A N   1 
ATOM   530   C CA  . ASP A 1 143 ? 157.392 79.901  89.638  1.00 153.23 ? 143 ASP A CA  1 
ATOM   531   C C   . ASP A 1 143 ? 156.561 78.709  89.128  1.00 154.47 ? 143 ASP A C   1 
ATOM   532   O O   . ASP A 1 143 ? 156.761 77.565  89.540  1.00 153.45 ? 143 ASP A O   1 
ATOM   533   C CB  . ASP A 1 143 ? 156.547 80.753  90.593  1.00 153.44 ? 143 ASP A CB  1 
ATOM   534   C CG  . ASP A 1 143 ? 156.078 79.940  91.806  1.00 155.55 ? 143 ASP A CG  1 
ATOM   535   O OD1 . ASP A 1 143 ? 156.942 79.335  92.474  1.00 155.48 ? 143 ASP A OD1 1 
ATOM   536   O OD2 . ASP A 1 143 ? 154.861 79.938  92.097  1.00 154.75 ? 143 ASP A OD2 1 
ATOM   537   N N   . LYS A 1 144 ? 155.651 78.972  88.182  1.00 151.74 ? 144 LYS A N   1 
ATOM   538   C CA  . LYS A 1 144 ? 154.767 77.983  87.549  1.00 150.34 ? 144 LYS A CA  1 
ATOM   539   C C   . LYS A 1 144 ? 155.549 76.914  86.770  1.00 151.39 ? 144 LYS A C   1 
ATOM   540   O O   . LYS A 1 144 ? 155.226 75.734  86.854  1.00 151.82 ? 144 LYS A O   1 
ATOM   541   C CB  . LYS A 1 144 ? 153.786 78.773  86.669  1.00 152.16 ? 144 LYS A CB  1 
ATOM   542   C CG  . LYS A 1 144 ? 152.571 78.003  86.137  1.00 152.01 ? 144 LYS A CG  1 
ATOM   543   C CD  . LYS A 1 144 ? 151.700 78.887  85.223  1.00 151.56 ? 144 LYS A CD  1 
ATOM   544   C CE  . LYS A 1 144 ? 151.127 80.128  85.928  1.00 150.89 ? 144 LYS A CE  1 
ATOM   545   N NZ  . LYS A 1 144 ? 150.448 81.054  84.991  1.00 149.51 ? 144 LYS A NZ  1 
ATOM   546   N N   . ASP A 1 145 ? 156.617 77.314  86.078  1.00 157.74 ? 145 ASP A N   1 
ATOM   547   C CA  . ASP A 1 145 ? 157.561 76.423  85.387  1.00 157.63 ? 145 ASP A CA  1 
ATOM   548   C C   . ASP A 1 145 ? 158.542 75.715  86.336  1.00 156.89 ? 145 ASP A C   1 
ATOM   549   O O   . ASP A 1 145 ? 159.068 74.656  85.983  1.00 157.15 ? 145 ASP A O   1 
ATOM   550   C CB  . ASP A 1 145 ? 158.351 77.215  84.331  1.00 158.64 ? 145 ASP A CB  1 
ATOM   551   C CG  . ASP A 1 145 ? 157.534 77.628  83.098  1.00 158.71 ? 145 ASP A CG  1 
ATOM   552   O OD1 . ASP A 1 145 ? 156.433 77.078  82.875  1.00 157.97 ? 145 ASP A OD1 1 
ATOM   553   O OD2 . ASP A 1 145 ? 158.038 78.442  82.293  1.00 157.87 ? 145 ASP A OD2 1 
ATOM   554   N N   . SER A 1 146 ? 158.797 76.250  87.535  1.00 158.29 ? 146 SER A N   1 
ATOM   555   C CA  . SER A 1 146 ? 159.636 75.579  88.536  1.00 158.17 ? 146 SER A CA  1 
ATOM   556   C C   . SER A 1 146 ? 158.938 74.407  89.243  1.00 158.81 ? 146 SER A C   1 
ATOM   557   O O   . SER A 1 146 ? 159.612 73.626  89.915  1.00 157.61 ? 146 SER A O   1 
ATOM   558   C CB  . SER A 1 146 ? 160.124 76.591  89.572  1.00 158.57 ? 146 SER A CB  1 
ATOM   559   O OG  . SER A 1 146 ? 161.098 75.998  90.405  1.00 159.70 ? 146 SER A OG  1 
ATOM   560   N N   . GLY A 1 147 ? 157.612 74.266  89.134  1.00 158.88 ? 147 GLY A N   1 
ATOM   561   C CA  . GLY A 1 147 ? 156.877 73.120  89.693  1.00 158.02 ? 147 GLY A CA  1 
ATOM   562   C C   . GLY A 1 147 ? 156.677 73.193  91.214  1.00 160.54 ? 147 GLY A C   1 
ATOM   563   O O   . GLY A 1 147 ? 156.645 72.169  91.899  1.00 160.31 ? 147 GLY A O   1 
ATOM   564   N N   . ASN A 1 148 ? 156.562 74.411  91.740  1.00 159.29 ? 148 ASN A N   1 
ATOM   565   C CA  . ASN A 1 148 ? 156.467 74.696  93.166  1.00 158.45 ? 148 ASN A CA  1 
ATOM   566   C C   . ASN A 1 148 ? 155.182 74.109  93.805  1.00 157.37 ? 148 ASN A C   1 
ATOM   567   O O   . ASN A 1 148 ? 154.085 74.397  93.319  1.00 155.82 ? 148 ASN A O   1 
ATOM   568   C CB  . ASN A 1 148 ? 156.542 76.225  93.289  1.00 157.11 ? 148 ASN A CB  1 
ATOM   569   C CG  . ASN A 1 148 ? 156.649 76.731  94.711  1.00 157.07 ? 148 ASN A CG  1 
ATOM   570   O OD1 . ASN A 1 148 ? 156.510 76.001  95.679  1.00 156.93 ? 148 ASN A OD1 1 
ATOM   571   N ND2 . ASN A 1 148 ? 156.898 77.999  94.879  1.00 156.91 ? 148 ASN A ND2 1 
ATOM   572   N N   . PRO A 1 149 ? 155.267 73.340  94.910  1.00 161.42 ? 149 PRO A N   1 
ATOM   573   C CA  . PRO A 1 149 ? 154.096 72.841  95.639  1.00 161.62 ? 149 PRO A CA  1 
ATOM   574   C C   . PRO A 1 149 ? 153.383 73.908  96.498  1.00 161.52 ? 149 PRO A C   1 
ATOM   575   O O   . PRO A 1 149 ? 152.266 73.670  96.957  1.00 159.60 ? 149 PRO A O   1 
ATOM   576   C CB  . PRO A 1 149 ? 154.636 71.697  96.507  1.00 161.48 ? 149 PRO A CB  1 
ATOM   577   C CG  . PRO A 1 149 ? 156.072 72.120  96.792  1.00 160.59 ? 149 PRO A CG  1 
ATOM   578   C CD  . PRO A 1 149 ? 156.489 72.799  95.490  1.00 161.28 ? 149 PRO A CD  1 
ATOM   579   N N   . LYS A 1 150 ? 154.003 75.071  96.732  1.00 158.02 ? 150 LYS A N   1 
ATOM   580   C CA  . LYS A 1 150 ? 153.491 76.182  97.555  1.00 155.96 ? 150 LYS A CA  1 
ATOM   581   C C   . LYS A 1 150 ? 153.586 77.493  96.770  1.00 155.84 ? 150 LYS A C   1 
ATOM   582   O O   . LYS A 1 150 ? 154.565 78.228  96.914  1.00 157.75 ? 150 LYS A O   1 
ATOM   583   C CB  . LYS A 1 150 ? 154.272 76.243  98.883  1.00 155.30 ? 150 LYS A CB  1 
ATOM   584   C CG  . LYS A 1 150 ? 154.071 75.001  99.760  1.00 155.45 ? 150 LYS A CG  1 
ATOM   585   C CD  . LYS A 1 150 ? 154.859 75.122  101.066 1.00 156.08 ? 150 LYS A CD  1 
ATOM   586   C CE  . LYS A 1 150 ? 154.681 73.854  101.901 1.00 156.02 ? 150 LYS A CE  1 
ATOM   587   N NZ  . LYS A 1 150 ? 155.447 73.916  103.164 1.00 155.32 ? 150 LYS A NZ  1 
ATOM   588   N N   . LEU A 1 151 ? 152.605 77.734  95.897  1.00 143.35 ? 151 LEU A N   1 
ATOM   589   C CA  . LEU A 1 151 ? 152.622 78.760  94.842  1.00 144.81 ? 151 LEU A CA  1 
ATOM   590   C C   . LEU A 1 151 ? 152.967 80.170  95.350  1.00 144.41 ? 151 LEU A C   1 
ATOM   591   O O   . LEU A 1 151 ? 152.481 80.601  96.395  1.00 143.26 ? 151 LEU A O   1 
ATOM   592   C CB  . LEU A 1 151 ? 151.259 78.798  94.124  1.00 145.81 ? 151 LEU A CB  1 
ATOM   593   C CG  . LEU A 1 151 ? 150.979 77.667  93.121  1.00 146.15 ? 151 LEU A CG  1 
ATOM   594   C CD1 . LEU A 1 151 ? 150.814 76.296  93.771  1.00 145.18 ? 151 LEU A CD1 1 
ATOM   595   C CD2 . LEU A 1 151 ? 149.695 77.980  92.356  1.00 143.70 ? 151 LEU A CD2 1 
ATOM   596   N N   . LEU A 1 152 ? 153.743 80.923  94.565  1.00 137.85 ? 152 LEU A N   1 
ATOM   597   C CA  . LEU A 1 152 ? 154.293 82.229  94.943  1.00 136.04 ? 152 LEU A CA  1 
ATOM   598   C C   . LEU A 1 152 ? 153.233 83.305  95.239  1.00 137.06 ? 152 LEU A C   1 
ATOM   599   O O   . LEU A 1 152 ? 153.445 84.152  96.100  1.00 136.54 ? 152 LEU A O   1 
ATOM   600   C CB  . LEU A 1 152 ? 155.289 82.638  93.845  1.00 134.88 ? 152 LEU A CB  1 
ATOM   601   C CG  . LEU A 1 152 ? 156.005 83.979  94.040  1.00 134.74 ? 152 LEU A CG  1 
ATOM   602   C CD1 . LEU A 1 152 ? 156.846 84.017  95.313  1.00 136.00 ? 152 LEU A CD1 1 
ATOM   603   C CD2 . LEU A 1 152 ? 156.929 84.228  92.855  1.00 136.24 ? 152 LEU A CD2 1 
ATOM   604   N N   . VAL A 1 153 ? 152.070 83.251  94.584  1.00 126.65 ? 153 VAL A N   1 
ATOM   605   C CA  . VAL A 1 153 ? 150.935 84.147  94.870  1.00 125.69 ? 153 VAL A CA  1 
ATOM   606   C C   . VAL A 1 153 ? 150.272 83.892  96.228  1.00 124.44 ? 153 VAL A C   1 
ATOM   607   O O   . VAL A 1 153 ? 149.706 84.816  96.804  1.00 121.37 ? 153 VAL A O   1 
ATOM   608   C CB  . VAL A 1 153 ? 149.853 84.070  93.777  1.00 122.44 ? 153 VAL A CB  1 
ATOM   609   C CG1 . VAL A 1 153 ? 150.287 84.801  92.515  1.00 122.21 ? 153 VAL A CG1 1 
ATOM   610   C CG2 . VAL A 1 153 ? 149.455 82.643  93.394  1.00 123.10 ? 153 VAL A CG2 1 
ATOM   611   N N   . ASN A 1 154 ? 150.348 82.663  96.749  1.00 126.90 ? 154 ASN A N   1 
ATOM   612   C CA  . ASN A 1 154 ? 149.693 82.248  97.996  1.00 124.79 ? 154 ASN A CA  1 
ATOM   613   C C   . ASN A 1 154 ? 150.645 82.194  99.201  1.00 125.40 ? 154 ASN A C   1 
ATOM   614   O O   . ASN A 1 154 ? 150.192 81.997  100.330 1.00 124.10 ? 154 ASN A O   1 
ATOM   615   C CB  . ASN A 1 154 ? 148.965 80.909  97.769  1.00 125.09 ? 154 ASN A CB  1 
ATOM   616   C CG  . ASN A 1 154 ? 147.842 81.001  96.757  1.00 128.03 ? 154 ASN A CG  1 
ATOM   617   O OD1 . ASN A 1 154 ? 147.286 82.056  96.508  1.00 127.90 ? 154 ASN A OD1 1 
ATOM   618   N ND2 . ASN A 1 154 ? 147.474 79.910  96.132  1.00 125.61 ? 154 ASN A ND2 1 
ATOM   619   N N   . ALA A 1 155 ? 151.950 82.376  98.996  1.00 120.74 ? 155 ALA A N   1 
ATOM   620   C CA  . ALA A 1 155 ? 152.916 82.542  100.073 1.00 117.07 ? 155 ALA A CA  1 
ATOM   621   C C   . ALA A 1 155 ? 152.692 83.860  100.828 1.00 116.86 ? 155 ALA A C   1 
ATOM   622   O O   . ALA A 1 155 ? 152.284 84.870  100.254 1.00 115.10 ? 155 ALA A O   1 
ATOM   623   C CB  . ALA A 1 155 ? 154.325 82.447  99.496  1.00 117.54 ? 155 ALA A CB  1 
ATOM   624   N N   . GLN A 1 156 ? 152.966 83.844  102.130 1.00 109.47 ? 156 GLN A N   1 
ATOM   625   C CA  . GLN A 1 156 ? 152.623 84.915  103.065 1.00 107.57 ? 156 GLN A CA  1 
ATOM   626   C C   . GLN A 1 156 ? 153.789 85.210  104.019 1.00 109.07 ? 156 GLN A C   1 
ATOM   627   O O   . GLN A 1 156 ? 154.626 84.345  104.269 1.00 109.42 ? 156 GLN A O   1 
ATOM   628   C CB  . GLN A 1 156 ? 151.402 84.501  103.897 1.00 106.83 ? 156 GLN A CB  1 
ATOM   629   C CG  . GLN A 1 156 ? 150.105 84.200  103.126 1.00 109.33 ? 156 GLN A CG  1 
ATOM   630   C CD  . GLN A 1 156 ? 149.366 83.016  103.746 1.00 109.30 ? 156 GLN A CD  1 
ATOM   631   O OE1 . GLN A 1 156 ? 148.904 83.061  104.874 1.00 105.67 ? 156 GLN A OE1 1 
ATOM   632   N NE2 . GLN A 1 156 ? 149.246 81.908  103.051 1.00 109.69 ? 156 GLN A NE2 1 
ATOM   633   N N   . CYS A 1 157 ? 153.816 86.406  104.610 1.00 104.52 ? 157 CYS A N   1 
ATOM   634   C CA  . CYS A 1 157 ? 154.703 86.702  105.728 1.00 104.85 ? 157 CYS A CA  1 
ATOM   635   C C   . CYS A 1 157 ? 154.349 85.840  106.956 1.00 106.96 ? 157 CYS A C   1 
ATOM   636   O O   . CYS A 1 157 ? 153.204 85.411  107.110 1.00 108.34 ? 157 CYS A O   1 
ATOM   637   C CB  . CYS A 1 157 ? 154.638 88.201  106.018 1.00 102.25 ? 157 CYS A CB  1 
ATOM   638   S SG  . CYS A 1 157 ? 155.199 89.130  104.569 1.00 99.88  ? 157 CYS A SG  1 
ATOM   639   N N   . THR A 1 158 ? 155.324 85.564  107.826 1.00 112.36 ? 158 THR A N   1 
ATOM   640   C CA  . THR A 1 158 ? 155.245 84.516  108.867 1.00 111.55 ? 158 THR A CA  1 
ATOM   641   C C   . THR A 1 158 ? 155.591 84.989  110.284 1.00 108.66 ? 158 THR A C   1 
ATOM   642   O O   . THR A 1 158 ? 155.379 84.249  111.242 1.00 104.49 ? 158 THR A O   1 
ATOM   643   C CB  . THR A 1 158 ? 156.187 83.358  108.511 1.00 112.21 ? 158 THR A CB  1 
ATOM   644   O OG1 . THR A 1 158 ? 157.485 83.856  108.299 1.00 114.13 ? 158 THR A OG1 1 
ATOM   645   C CG2 . THR A 1 158 ? 155.774 82.611  107.256 1.00 108.92 ? 158 THR A CG2 1 
ATOM   646   N N   . ASP A 1 159 ? 156.129 86.194  110.455 1.00 110.87 ? 159 ASP A N   1 
ATOM   647   C CA  . ASP A 1 159 ? 156.497 86.751  111.762 1.00 108.99 ? 159 ASP A CA  1 
ATOM   648   C C   . ASP A 1 159 ? 155.274 87.251  112.548 1.00 107.91 ? 159 ASP A C   1 
ATOM   649   O O   . ASP A 1 159 ? 154.215 87.499  111.985 1.00 110.10 ? 159 ASP A O   1 
ATOM   650   C CB  . ASP A 1 159 ? 157.480 87.899  111.547 1.00 109.06 ? 159 ASP A CB  1 
ATOM   651   C CG  . ASP A 1 159 ? 156.847 88.994  110.693 1.00 113.11 ? 159 ASP A CG  1 
ATOM   652   O OD1 . ASP A 1 159 ? 156.914 88.871  109.446 1.00 113.61 ? 159 ASP A OD1 1 
ATOM   653   O OD2 . ASP A 1 159 ? 156.259 89.922  111.290 1.00 114.25 ? 159 ASP A OD2 1 
ATOM   654   N N   . GLU A 1 160 ? 155.411 87.441  113.859 1.00 103.65 ? 160 GLU A N   1 
ATOM   655   C CA  . GLU A 1 160 ? 154.286 87.769  114.739 1.00 102.68 ? 160 GLU A CA  1 
ATOM   656   C C   . GLU A 1 160 ? 153.575 89.095  114.422 1.00 103.79 ? 160 GLU A C   1 
ATOM   657   O O   . GLU A 1 160 ? 152.431 89.269  114.841 1.00 104.89 ? 160 GLU A O   1 
ATOM   658   C CB  . GLU A 1 160 ? 154.736 87.716  116.212 1.00 102.33 ? 160 GLU A CB  1 
ATOM   659   C CG  . GLU A 1 160 ? 155.662 88.847  116.702 1.00 106.11 ? 160 GLU A CG  1 
ATOM   660   C CD  . GLU A 1 160 ? 157.134 88.741  116.257 1.00 109.91 ? 160 GLU A CD  1 
ATOM   661   O OE1 . GLU A 1 160 ? 157.542 87.706  115.680 1.00 110.06 ? 160 GLU A OE1 1 
ATOM   662   O OE2 . GLU A 1 160 ? 157.898 89.695  116.521 1.00 105.25 ? 160 GLU A OE2 1 
ATOM   663   N N   . PHE A 1 161 ? 154.196 90.026  113.693 1.00 91.18  ? 161 PHE A N   1 
ATOM   664   C CA  . PHE A 1 161 ? 153.556 91.277  113.288 1.00 91.65  ? 161 PHE A CA  1 
ATOM   665   C C   . PHE A 1 161 ? 152.867 91.168  111.936 1.00 92.34  ? 161 PHE A C   1 
ATOM   666   O O   . PHE A 1 161 ? 151.707 91.559  111.836 1.00 91.63  ? 161 PHE A O   1 
ATOM   667   C CB  . PHE A 1 161 ? 154.560 92.426  113.308 1.00 87.64  ? 161 PHE A CB  1 
ATOM   668   C CG  . PHE A 1 161 ? 154.822 92.943  114.702 1.00 92.97  ? 161 PHE A CG  1 
ATOM   669   C CD1 . PHE A 1 161 ? 153.927 93.861  115.278 1.00 93.75  ? 161 PHE A CD1 1 
ATOM   670   C CD2 . PHE A 1 161 ? 155.939 92.507  115.430 1.00 93.11  ? 161 PHE A CD2 1 
ATOM   671   C CE1 . PHE A 1 161 ? 154.151 94.345  116.574 1.00 92.63  ? 161 PHE A CE1 1 
ATOM   672   C CE2 . PHE A 1 161 ? 156.170 92.998  116.726 1.00 94.15  ? 161 PHE A CE2 1 
ATOM   673   C CZ  . PHE A 1 161 ? 155.277 93.920  117.296 1.00 96.67  ? 161 PHE A CZ  1 
ATOM   674   N N   . TYR A 1 162 ? 153.516 90.615  110.916 1.00 94.28  ? 162 TYR A N   1 
ATOM   675   C CA  . TYR A 1 162 ? 152.984 90.606  109.551 1.00 92.67  ? 162 TYR A CA  1 
ATOM   676   C C   . TYR A 1 162 ? 152.396 89.261  109.108 1.00 95.07  ? 162 TYR A C   1 
ATOM   677   O O   . TYR A 1 162 ? 152.122 89.085  107.927 1.00 99.54  ? 162 TYR A O   1 
ATOM   678   C CB  . TYR A 1 162 ? 154.015 91.170  108.564 1.00 90.67  ? 162 TYR A CB  1 
ATOM   679   C CG  . TYR A 1 162 ? 154.551 92.524  108.988 1.00 91.91  ? 162 TYR A CG  1 
ATOM   680   C CD1 . TYR A 1 162 ? 153.705 93.649  108.972 1.00 92.59  ? 162 TYR A CD1 1 
ATOM   681   C CD2 . TYR A 1 162 ? 155.861 92.645  109.482 1.00 91.98  ? 162 TYR A CD2 1 
ATOM   682   C CE1 . TYR A 1 162 ? 154.156 94.878  109.482 1.00 93.00  ? 162 TYR A CE1 1 
ATOM   683   C CE2 . TYR A 1 162 ? 156.311 93.872  110.004 1.00 92.47  ? 162 TYR A CE2 1 
ATOM   684   C CZ  . TYR A 1 162 ? 155.449 94.985  110.022 1.00 90.55  ? 162 TYR A CZ  1 
ATOM   685   O OH  . TYR A 1 162 ? 155.857 96.154  110.566 1.00 85.47  ? 162 TYR A OH  1 
ATOM   686   N N   . GLN A 1 163 ? 152.160 88.308  110.013 1.00 100.78 ? 163 GLN A N   1 
ATOM   687   C CA  . GLN A 1 163 ? 151.664 86.976  109.655 1.00 98.90  ? 163 GLN A CA  1 
ATOM   688   C C   . GLN A 1 163 ? 150.457 87.019  108.709 1.00 96.90  ? 163 GLN A C   1 
ATOM   689   O O   . GLN A 1 163 ? 149.493 87.751  108.936 1.00 99.36  ? 163 GLN A O   1 
ATOM   690   C CB  . GLN A 1 163 ? 151.342 86.154  110.911 1.00 98.73  ? 163 GLN A CB  1 
ATOM   691   C CG  . GLN A 1 163 ? 151.063 84.684  110.580 1.00 98.27  ? 163 GLN A CG  1 
ATOM   692   C CD  . GLN A 1 163 ? 151.031 83.797  111.822 1.00 104.39 ? 163 GLN A CD  1 
ATOM   693   O OE1 . GLN A 1 163 ? 151.012 84.247  112.957 1.00 103.48 ? 163 GLN A OE1 1 
ATOM   694   N NE2 . GLN A 1 163 ? 151.008 82.497  111.653 1.00 101.68 ? 163 GLN A NE2 1 
ATOM   695   N N   . GLY A 1 164 ? 150.503 86.233  107.638 1.00 90.97  ? 164 GLY A N   1 
ATOM   696   C CA  . GLY A 1 164 ? 149.412 86.116  106.673 1.00 90.65  ? 164 GLY A CA  1 
ATOM   697   C C   . GLY A 1 164 ? 149.330 87.245  105.642 1.00 90.74  ? 164 GLY A C   1 
ATOM   698   O O   . GLY A 1 164 ? 148.548 87.147  104.700 1.00 94.62  ? 164 GLY A O   1 
ATOM   699   N N   . HIS A 1 165 ? 150.132 88.302  105.774 1.00 81.84  ? 165 HIS A N   1 
ATOM   700   C CA  . HIS A 1 165 ? 150.251 89.353  104.758 1.00 79.65  ? 165 HIS A CA  1 
ATOM   701   C C   . HIS A 1 165 ? 150.745 88.781  103.433 1.00 80.81  ? 165 HIS A C   1 
ATOM   702   O O   . HIS A 1 165 ? 151.640 87.936  103.421 1.00 89.34  ? 165 HIS A O   1 
ATOM   703   C CB  . HIS A 1 165 ? 151.212 90.424  105.257 1.00 86.54  ? 165 HIS A CB  1 
ATOM   704   C CG  . HIS A 1 165 ? 151.352 91.603  104.344 1.00 89.59  ? 165 HIS A CG  1 
ATOM   705   N ND1 . HIS A 1 165 ? 150.292 92.298  103.779 1.00 88.03  ? 165 HIS A ND1 1 
ATOM   706   C CD2 . HIS A 1 165 ? 152.516 92.229  104.027 1.00 89.53  ? 165 HIS A CD2 1 
ATOM   707   C CE1 . HIS A 1 165 ? 150.841 93.323  103.117 1.00 84.91  ? 165 HIS A CE1 1 
ATOM   708   N NE2 . HIS A 1 165 ? 152.174 93.310  103.254 1.00 83.44  ? 165 HIS A NE2 1 
ATOM   709   N N   . SER A 1 166 ? 150.181 89.220  102.315 1.00 79.39  ? 166 SER A N   1 
ATOM   710   C CA  . SER A 1 166 ? 150.425 88.627  100.999 1.00 85.41  ? 166 SER A CA  1 
ATOM   711   C C   . SER A 1 166 ? 150.582 89.686  99.920  1.00 86.49  ? 166 SER A C   1 
ATOM   712   O O   . SER A 1 166 ? 150.179 90.836  100.082 1.00 89.31  ? 166 SER A O   1 
ATOM   713   C CB  . SER A 1 166 ? 149.308 87.643  100.625 1.00 90.27  ? 166 SER A CB  1 
ATOM   714   O OG  . SER A 1 166 ? 148.180 88.312  100.096 1.00 86.54  ? 166 SER A OG  1 
ATOM   715   N N   . ALA A 1 167 ? 151.134 89.296  98.775  1.00 92.26  ? 167 ALA A N   1 
ATOM   716   C CA  . ALA A 1 167 ? 151.289 90.190  97.627  1.00 94.42  ? 167 ALA A CA  1 
ATOM   717   C C   . ALA A 1 167 ? 149.964 90.832  97.180  1.00 94.30  ? 167 ALA A C   1 
ATOM   718   O O   . ALA A 1 167 ? 149.965 91.978  96.737  1.00 95.55  ? 167 ALA A O   1 
ATOM   719   C CB  . ALA A 1 167 ? 151.929 89.391  96.496  1.00 94.13  ? 167 ALA A CB  1 
ATOM   720   N N   . LEU A 1 168 ? 148.828 90.136  97.318  1.00 89.54  ? 168 LEU A N   1 
ATOM   721   C CA  . LEU A 1 168 ? 147.509 90.685  96.994  1.00 91.67  ? 168 LEU A CA  1 
ATOM   722   C C   . LEU A 1 168 ? 147.098 91.809  97.956  1.00 91.84  ? 168 LEU A C   1 
ATOM   723   O O   . LEU A 1 168 ? 146.624 92.847  97.509  1.00 97.16  ? 168 LEU A O   1 
ATOM   724   C CB  . LEU A 1 168 ? 146.489 89.534  96.940  1.00 90.57  ? 168 LEU A CB  1 
ATOM   725   C CG  . LEU A 1 168 ? 145.044 89.953  96.619  1.00 89.02  ? 168 LEU A CG  1 
ATOM   726   C CD1 . LEU A 1 168 ? 144.912 90.645  95.264  1.00 87.42  ? 168 LEU A CD1 1 
ATOM   727   C CD2 . LEU A 1 168 ? 144.148 88.723  96.588  1.00 90.92  ? 168 LEU A CD2 1 
ATOM   728   N N   . HIS A 1 169 ? 147.359 91.687  99.260  1.00 76.73  ? 169 HIS A N   1 
ATOM   729   C CA  . HIS A 1 169 ? 147.156 92.799  100.193 1.00 76.54  ? 169 HIS A CA  1 
ATOM   730   C C   . HIS A 1 169 ? 148.075 93.995  99.898  1.00 82.99  ? 169 HIS A C   1 
ATOM   731   O O   . HIS A 1 169 ? 147.688 95.140  100.125 1.00 83.80  ? 169 HIS A O   1 
ATOM   732   C CB  . HIS A 1 169 ? 147.379 92.339  101.631 1.00 76.35  ? 169 HIS A CB  1 
ATOM   733   C CG  . HIS A 1 169 ? 146.512 91.208  102.102 1.00 77.51  ? 169 HIS A CG  1 
ATOM   734   N ND1 . HIS A 1 169 ? 146.790 89.855  101.938 1.00 80.17  ? 169 HIS A ND1 1 
ATOM   735   C CD2 . HIS A 1 169 ? 145.396 91.341  102.873 1.00 78.61  ? 169 HIS A CD2 1 
ATOM   736   C CE1 . HIS A 1 169 ? 145.840 89.204  102.622 1.00 79.00  ? 169 HIS A CE1 1 
ATOM   737   N NE2 . HIS A 1 169 ? 144.993 90.071  103.191 1.00 80.70  ? 169 HIS A NE2 1 
ATOM   738   N N   . ILE A 1 170 ? 149.286 93.773  99.379  1.00 91.77  ? 170 ILE A N   1 
ATOM   739   C CA  . ILE A 1 170 ? 150.161 94.864  98.922  1.00 91.30  ? 170 ILE A CA  1 
ATOM   740   C C   . ILE A 1 170 ? 149.565 95.525  97.680  1.00 93.97  ? 170 ILE A C   1 
ATOM   741   O O   . ILE A 1 170 ? 149.444 96.746  97.633  1.00 96.47  ? 170 ILE A O   1 
ATOM   742   C CB  . ILE A 1 170 ? 151.606 94.390  98.658  1.00 86.38  ? 170 ILE A CB  1 
ATOM   743   C CG1 . ILE A 1 170 ? 152.217 93.749  99.915  1.00 87.13  ? 170 ILE A CG1 1 
ATOM   744   C CG2 . ILE A 1 170 ? 152.489 95.566  98.219  1.00 86.64  ? 170 ILE A CG2 1 
ATOM   745   C CD1 . ILE A 1 170 ? 153.591 93.130  99.688  1.00 89.82  ? 170 ILE A CD1 1 
ATOM   746   N N   . ALA A 1 171 ? 149.141 94.738  96.694  1.00 89.33  ? 171 ALA A N   1 
ATOM   747   C CA  . ALA A 1 171 ? 148.553 95.241  95.455  1.00 84.50  ? 171 ALA A CA  1 
ATOM   748   C C   . ALA A 1 171 ? 147.315 96.115  95.701  1.00 87.18  ? 171 ALA A C   1 
ATOM   749   O O   . ALA A 1 171 ? 147.140 97.147  95.056  1.00 88.64  ? 171 ALA A O   1 
ATOM   750   C CB  . ALA A 1 171 ? 148.210 94.042  94.571  1.00 82.21  ? 171 ALA A CB  1 
ATOM   751   N N   . ILE A 1 172 ? 146.462 95.725  96.646  1.00 87.94  ? 172 ILE A N   1 
ATOM   752   C CA  . ILE A 1 172 ? 145.270 96.492  96.998  1.00 82.72  ? 172 ILE A CA  1 
ATOM   753   C C   . ILE A 1 172 ? 145.646 97.764  97.760  1.00 85.10  ? 172 ILE A C   1 
ATOM   754   O O   . ILE A 1 172 ? 145.125 98.824  97.434  1.00 86.36  ? 172 ILE A O   1 
ATOM   755   C CB  . ILE A 1 172 ? 144.264 95.620  97.769  1.00 79.10  ? 172 ILE A CB  1 
ATOM   756   C CG1 . ILE A 1 172 ? 143.788 94.443  96.898  1.00 82.87  ? 172 ILE A CG1 1 
ATOM   757   C CG2 . ILE A 1 172 ? 143.040 96.445  98.188  1.00 82.80  ? 172 ILE A CG2 1 
ATOM   758   C CD1 . ILE A 1 172 ? 143.148 93.319  97.691  1.00 81.25  ? 172 ILE A CD1 1 
ATOM   759   N N   . GLU A 1 173 ? 146.565 97.732  98.728  1.00 92.57  ? 173 GLU A N   1 
ATOM   760   C CA  . GLU A 1 173 ? 146.949 98.955  99.450  1.00 90.29  ? 173 GLU A CA  1 
ATOM   761   C C   . GLU A 1 173 ? 147.660 99.970  98.551  1.00 93.68  ? 173 GLU A C   1 
ATOM   762   O O   . GLU A 1 173 ? 147.382 101.164 98.642  1.00 95.59  ? 173 GLU A O   1 
ATOM   763   C CB  . GLU A 1 173 ? 147.800 98.613  100.675 1.00 92.49  ? 173 GLU A CB  1 
ATOM   764   C CG  . GLU A 1 173 ? 148.086 99.837  101.566 1.00 95.30  ? 173 GLU A CG  1 
ATOM   765   C CD  . GLU A 1 173 ? 149.262 100.733 101.120 1.00 100.14 ? 173 GLU A CD  1 
ATOM   766   O OE1 . GLU A 1 173 ? 150.171 100.276 100.389 1.00 100.32 ? 173 GLU A OE1 1 
ATOM   767   O OE2 . GLU A 1 173 ? 149.297 101.907 101.555 1.00 97.34  ? 173 GLU A OE2 1 
ATOM   768   N N   . LYS A 1 174 ? 148.498 99.504  97.620  1.00 97.20  ? 174 LYS A N   1 
ATOM   769   C CA  . LYS A 1 174 ? 149.120 100.307 96.550  1.00 95.22  ? 174 LYS A CA  1 
ATOM   770   C C   . LYS A 1 174 ? 148.124 100.773 95.471  1.00 98.04  ? 174 LYS A C   1 
ATOM   771   O O   . LYS A 1 174 ? 148.524 101.448 94.525  1.00 95.82  ? 174 LYS A O   1 
ATOM   772   C CB  . LYS A 1 174 ? 150.298 99.512  95.957  1.00 94.13  ? 174 LYS A CB  1 
ATOM   773   C CG  . LYS A 1 174 ? 151.456 99.322  96.953  1.00 97.35  ? 174 LYS A CG  1 
ATOM   774   C CD  . LYS A 1 174 ? 152.280 100.599 97.152  1.00 99.27  ? 174 LYS A CD  1 
ATOM   775   C CE  . LYS A 1 174 ? 153.267 100.481 98.319  1.00 99.54  ? 174 LYS A CE  1 
ATOM   776   N NZ  . LYS A 1 174 ? 152.695 100.973 99.595  1.00 95.09  ? 174 LYS A NZ  1 
ATOM   777   N N   . ARG A 1 175 ? 146.832 100.448 95.593  1.00 96.20  ? 175 ARG A N   1 
ATOM   778   C CA  . ARG A 1 175 ? 145.708 100.874 94.732  1.00 90.42  ? 175 ARG A CA  1 
ATOM   779   C C   . ARG A 1 175 ? 145.775 100.446 93.260  1.00 91.77  ? 175 ARG A C   1 
ATOM   780   O O   . ARG A 1 175 ? 145.150 101.079 92.409  1.00 92.66  ? 175 ARG A O   1 
ATOM   781   C CB  . ARG A 1 175 ? 145.421 102.382 94.874  1.00 93.04  ? 175 ARG A CB  1 
ATOM   782   C CG  . ARG A 1 175 ? 145.245 102.858 96.315  1.00 92.08  ? 175 ARG A CG  1 
ATOM   783   C CD  . ARG A 1 175 ? 144.898 104.350 96.370  1.00 91.61  ? 175 ARG A CD  1 
ATOM   784   N NE  . ARG A 1 175 ? 143.548 104.646 95.850  1.00 99.96  ? 175 ARG A NE  1 
ATOM   785   C CZ  . ARG A 1 175 ? 142.409 104.542 96.504  1.00 97.15  ? 175 ARG A CZ  1 
ATOM   786   N NH1 . ARG A 1 175 ? 141.291 104.896 95.947  1.00 91.31  ? 175 ARG A NH1 1 
ATOM   787   N NH2 . ARG A 1 175 ? 142.371 104.084 97.717  1.00 92.60  ? 175 ARG A NH2 1 
ATOM   788   N N   . SER A 1 176 ? 146.521 99.397  92.919  1.00 106.64 ? 176 SER A N   1 
ATOM   789   C CA  . SER A 1 176 ? 146.641 98.952  91.524  1.00 108.42 ? 176 SER A CA  1 
ATOM   790   C C   . SER A 1 176 ? 145.615 97.877  91.175  1.00 107.17 ? 176 SER A C   1 
ATOM   791   O O   . SER A 1 176 ? 145.837 96.687  91.399  1.00 108.10 ? 176 SER A O   1 
ATOM   792   C CB  . SER A 1 176 ? 148.062 98.488  91.214  1.00 108.72 ? 176 SER A CB  1 
ATOM   793   O OG  . SER A 1 176 ? 148.111 98.019  89.877  1.00 109.80 ? 176 SER A OG  1 
ATOM   794   N N   . LEU A 1 177 ? 144.504 98.274  90.549  1.00 108.37 ? 177 LEU A N   1 
ATOM   795   C CA  . LEU A 1 177 ? 143.553 97.324  89.966  1.00 111.60 ? 177 LEU A CA  1 
ATOM   796   C C   . LEU A 1 177 ? 144.232 96.428  88.922  1.00 110.50 ? 177 LEU A C   1 
ATOM   797   O O   . LEU A 1 177 ? 143.946 95.238  88.852  1.00 112.12 ? 177 LEU A O   1 
ATOM   798   C CB  . LEU A 1 177 ? 142.371 98.098  89.357  1.00 112.46 ? 177 LEU A CB  1 
ATOM   799   C CG  . LEU A 1 177 ? 141.339 97.211  88.633  1.00 109.51 ? 177 LEU A CG  1 
ATOM   800   C CD1 . LEU A 1 177 ? 140.621 96.260  89.587  1.00 108.01 ? 177 LEU A CD1 1 
ATOM   801   C CD2 . LEU A 1 177 ? 140.291 98.083  87.951  1.00 107.01 ? 177 LEU A CD2 1 
ATOM   802   N N   . GLN A 1 178 ? 145.166 96.973  88.137  1.00 114.56 ? 178 GLN A N   1 
ATOM   803   C CA  . GLN A 1 178 ? 145.917 96.220  87.133  1.00 114.35 ? 178 GLN A CA  1 
ATOM   804   C C   . GLN A 1 178 ? 146.734 95.085  87.767  1.00 113.36 ? 178 GLN A C   1 
ATOM   805   O O   . GLN A 1 178 ? 146.765 93.975  87.236  1.00 112.43 ? 178 GLN A O   1 
ATOM   806   C CB  . GLN A 1 178 ? 146.847 97.171  86.357  1.00 113.21 ? 178 GLN A CB  1 
ATOM   807   C CG  . GLN A 1 178 ? 146.128 98.104  85.367  1.00 114.33 ? 178 GLN A CG  1 
ATOM   808   C CD  . GLN A 1 178 ? 145.365 99.272  85.986  1.00 114.82 ? 178 GLN A CD  1 
ATOM   809   O OE1 . GLN A 1 178 ? 145.515 99.628  87.148  1.00 113.79 ? 178 GLN A OE1 1 
ATOM   810   N NE2 . GLN A 1 178 ? 144.507 99.919  85.236  1.00 113.85 ? 178 GLN A NE2 1 
ATOM   811   N N   . CYS A 1 179 ? 147.352 95.327  88.922  1.00 111.40 ? 179 CYS A N   1 
ATOM   812   C CA  . CYS A 1 179 ? 148.098 94.303  89.635  1.00 110.65 ? 179 CYS A CA  1 
ATOM   813   C C   . CYS A 1 179 ? 147.170 93.308  90.358  1.00 113.97 ? 179 CYS A C   1 
ATOM   814   O O   . CYS A 1 179 ? 147.422 92.105  90.307  1.00 112.97 ? 179 CYS A O   1 
ATOM   815   C CB  . CYS A 1 179 ? 149.088 95.002  90.566  1.00 112.86 ? 179 CYS A CB  1 
ATOM   816   S SG  . CYS A 1 179 ? 150.295 93.788  91.135  1.00 122.79 ? 179 CYS A SG  1 
ATOM   817   N N   . VAL A 1 180 ? 146.051 93.759  90.943  1.00 106.09 ? 180 VAL A N   1 
ATOM   818   C CA  . VAL A 1 180 ? 145.036 92.855  91.520  1.00 104.52 ? 180 VAL A CA  1 
ATOM   819   C C   . VAL A 1 180 ? 144.522 91.867  90.478  1.00 105.26 ? 180 VAL A C   1 
ATOM   820   O O   . VAL A 1 180 ? 144.536 90.662  90.713  1.00 103.82 ? 180 VAL A O   1 
ATOM   821   C CB  . VAL A 1 180 ? 143.872 93.641  92.139  1.00 102.29 ? 180 VAL A CB  1 
ATOM   822   C CG1 . VAL A 1 180 ? 142.692 92.742  92.508  1.00 105.33 ? 180 VAL A CG1 1 
ATOM   823   C CG2 . VAL A 1 180 ? 144.331 94.338  93.413  1.00 101.61 ? 180 VAL A CG2 1 
ATOM   824   N N   . LYS A 1 181 ? 144.136 92.360  89.299  1.00 111.00 ? 181 LYS A N   1 
ATOM   825   C CA  . LYS A 1 181 ? 143.755 91.519  88.162  1.00 107.80 ? 181 LYS A CA  1 
ATOM   826   C C   . LYS A 1 181 ? 144.860 90.520  87.813  1.00 111.09 ? 181 LYS A C   1 
ATOM   827   O O   . LYS A 1 181 ? 144.600 89.327  87.763  1.00 110.43 ? 181 LYS A O   1 
ATOM   828   C CB  . LYS A 1 181 ? 143.429 92.398  86.946  1.00 105.16 ? 181 LYS A CB  1 
ATOM   829   C CG  . LYS A 1 181 ? 142.090 93.124  87.101  1.00 110.28 ? 181 LYS A CG  1 
ATOM   830   C CD  . LYS A 1 181 ? 141.813 94.025  85.896  1.00 111.07 ? 181 LYS A CD  1 
ATOM   831   C CE  . LYS A 1 181 ? 140.397 94.595  85.965  1.00 111.96 ? 181 LYS A CE  1 
ATOM   832   N NZ  . LYS A 1 181 ? 140.067 95.366  84.746  1.00 108.69 ? 181 LYS A NZ  1 
ATOM   833   N N   . LEU A 1 182 ? 146.097 90.971  87.600  1.00 117.54 ? 182 LEU A N   1 
ATOM   834   C CA  . LEU A 1 182 ? 147.208 90.093  87.226  1.00 114.53 ? 182 LEU A CA  1 
ATOM   835   C C   . LEU A 1 182 ? 147.465 88.973  88.255  1.00 116.08 ? 182 LEU A C   1 
ATOM   836   O O   . LEU A 1 182 ? 147.730 87.830  87.879  1.00 116.84 ? 182 LEU A O   1 
ATOM   837   C CB  . LEU A 1 182 ? 148.449 90.979  87.007  1.00 116.23 ? 182 LEU A CB  1 
ATOM   838   C CG  . LEU A 1 182 ? 149.733 90.228  86.623  1.00 117.58 ? 182 LEU A CG  1 
ATOM   839   C CD1 . LEU A 1 182 ? 149.595 89.463  85.312  1.00 116.56 ? 182 LEU A CD1 1 
ATOM   840   C CD2 . LEU A 1 182 ? 150.869 91.231  86.453  1.00 115.41 ? 182 LEU A CD2 1 
ATOM   841   N N   . LEU A 1 183 ? 147.375 89.278  89.549  1.00 108.77 ? 183 LEU A N   1 
ATOM   842   C CA  . LEU A 1 183 ? 147.534 88.300  90.625  1.00 110.13 ? 183 LEU A CA  1 
ATOM   843   C C   . LEU A 1 183 ? 146.373 87.297  90.676  1.00 111.60 ? 183 LEU A C   1 
ATOM   844   O O   . LEU A 1 183 ? 146.607 86.090  90.728  1.00 108.26 ? 183 LEU A O   1 
ATOM   845   C CB  . LEU A 1 183 ? 147.658 89.047  91.965  1.00 110.15 ? 183 LEU A CB  1 
ATOM   846   C CG  . LEU A 1 183 ? 148.973 89.819  92.152  1.00 106.70 ? 183 LEU A CG  1 
ATOM   847   C CD1 . LEU A 1 183 ? 148.858 90.712  93.380  1.00 106.17 ? 183 LEU A CD1 1 
ATOM   848   C CD2 . LEU A 1 183 ? 150.149 88.872  92.372  1.00 110.44 ? 183 LEU A CD2 1 
ATOM   849   N N   . VAL A 1 184 ? 145.126 87.774  90.648  1.00 115.57 ? 184 VAL A N   1 
ATOM   850   C CA  . VAL A 1 184 ? 143.929 86.918  90.718  1.00 112.66 ? 184 VAL A CA  1 
ATOM   851   C C   . VAL A 1 184 ? 143.772 86.053  89.462  1.00 112.23 ? 184 VAL A C   1 
ATOM   852   O O   . VAL A 1 184 ? 143.444 84.872  89.572  1.00 113.04 ? 184 VAL A O   1 
ATOM   853   C CB  . VAL A 1 184 ? 142.680 87.774  90.989  1.00 109.50 ? 184 VAL A CB  1 
ATOM   854   C CG1 . VAL A 1 184 ? 141.380 86.974  90.890  1.00 111.27 ? 184 VAL A CG1 1 
ATOM   855   C CG2 . VAL A 1 184 ? 142.724 88.375  92.397  1.00 111.41 ? 184 VAL A CG2 1 
ATOM   856   N N   . GLU A 1 185 ? 144.092 86.573  88.275  1.00 113.59 ? 185 GLU A N   1 
ATOM   857   C CA  . GLU A 1 185 ? 144.153 85.788  87.030  1.00 114.89 ? 185 GLU A CA  1 
ATOM   858   C C   . GLU A 1 185 ? 145.166 84.635  87.108  1.00 118.09 ? 185 GLU A C   1 
ATOM   859   O O   . GLU A 1 185 ? 144.936 83.569  86.541  1.00 119.45 ? 185 GLU A O   1 
ATOM   860   C CB  . GLU A 1 185 ? 144.525 86.706  85.855  1.00 115.29 ? 185 GLU A CB  1 
ATOM   861   C CG  . GLU A 1 185 ? 143.350 87.589  85.409  1.00 117.19 ? 185 GLU A CG  1 
ATOM   862   C CD  . GLU A 1 185 ? 143.742 88.718  84.437  1.00 119.55 ? 185 GLU A CD  1 
ATOM   863   O OE1 . GLU A 1 185 ? 144.861 88.710  83.877  1.00 119.23 ? 185 GLU A OE1 1 
ATOM   864   O OE2 . GLU A 1 185 ? 142.892 89.599  84.178  1.00 118.53 ? 185 GLU A OE2 1 
ATOM   865   N N   . ASN A 1 186 ? 146.272 84.811  87.834  1.00 121.38 ? 186 ASN A N   1 
ATOM   866   C CA  . ASN A 1 186 ? 147.257 83.758  88.099  1.00 120.53 ? 186 ASN A CA  1 
ATOM   867   C C   . ASN A 1 186 ? 146.954 82.913  89.351  1.00 120.44 ? 186 ASN A C   1 
ATOM   868   O O   . ASN A 1 186 ? 147.782 82.100  89.764  1.00 117.17 ? 186 ASN A O   1 
ATOM   869   C CB  . ASN A 1 186 ? 148.657 84.382  88.088  1.00 120.06 ? 186 ASN A CB  1 
ATOM   870   C CG  . ASN A 1 186 ? 149.103 84.640  86.664  1.00 122.07 ? 186 ASN A CG  1 
ATOM   871   O OD1 . ASN A 1 186 ? 149.563 83.738  85.974  1.00 124.20 ? 186 ASN A OD1 1 
ATOM   872   N ND2 . ASN A 1 186 ? 148.958 85.849  86.179  1.00 121.19 ? 186 ASN A ND2 1 
ATOM   873   N N   . GLY A 1 187 ? 145.760 83.047  89.933  1.00 117.40 ? 187 GLY A N   1 
ATOM   874   C CA  . GLY A 1 187 ? 145.275 82.174  91.007  1.00 115.80 ? 187 GLY A CA  1 
ATOM   875   C C   . GLY A 1 187 ? 145.622 82.608  92.433  1.00 116.56 ? 187 GLY A C   1 
ATOM   876   O O   . GLY A 1 187 ? 145.616 81.763  93.327  1.00 113.65 ? 187 GLY A O   1 
ATOM   877   N N   . ALA A 1 188 ? 145.921 83.889  92.662  1.00 115.74 ? 188 ALA A N   1 
ATOM   878   C CA  . ALA A 1 188 ? 146.098 84.422  94.011  1.00 116.09 ? 188 ALA A CA  1 
ATOM   879   C C   . ALA A 1 188 ? 144.826 84.248  94.849  1.00 114.51 ? 188 ALA A C   1 
ATOM   880   O O   . ALA A 1 188 ? 143.759 84.717  94.457  1.00 115.47 ? 188 ALA A O   1 
ATOM   881   C CB  . ALA A 1 188 ? 146.479 85.902  93.929  1.00 116.02 ? 188 ALA A CB  1 
ATOM   882   N N   . ASP A 1 189 ? 144.928 83.578  95.994  1.00 112.26 ? 189 ASP A N   1 
ATOM   883   C CA  . ASP A 1 189 ? 143.778 83.280  96.841  1.00 112.03 ? 189 ASP A CA  1 
ATOM   884   C C   . ASP A 1 189 ? 143.184 84.557  97.455  1.00 114.47 ? 189 ASP A C   1 
ATOM   885   O O   . ASP A 1 189 ? 143.787 85.224  98.294  1.00 113.04 ? 189 ASP A O   1 
ATOM   886   C CB  . ASP A 1 189 ? 144.150 82.227  97.891  1.00 110.14 ? 189 ASP A CB  1 
ATOM   887   C CG  . ASP A 1 189 ? 142.994 81.866  98.838  1.00 113.47 ? 189 ASP A CG  1 
ATOM   888   O OD1 . ASP A 1 189 ? 141.831 82.237  98.561  1.00 115.63 ? 189 ASP A OD1 1 
ATOM   889   O OD2 . ASP A 1 189 ? 143.254 81.158  99.834  1.00 113.24 ? 189 ASP A OD2 1 
ATOM   890   N N   . VAL A 1 190 ? 141.969 84.894  97.041  1.00 104.43 ? 190 VAL A N   1 
ATOM   891   C CA  . VAL A 1 190 ? 141.226 86.078  97.472  1.00 99.99  ? 190 VAL A CA  1 
ATOM   892   C C   . VAL A 1 190 ? 140.819 86.022  98.952  1.00 101.91 ? 190 VAL A C   1 
ATOM   893   O O   . VAL A 1 190 ? 140.432 87.044  99.509  1.00 102.62 ? 190 VAL A O   1 
ATOM   894   C CB  . VAL A 1 190 ? 140.029 86.261  96.518  1.00 99.69  ? 190 VAL A CB  1 
ATOM   895   C CG1 . VAL A 1 190 ? 139.023 87.319  96.945  1.00 106.26 ? 190 VAL A CG1 1 
ATOM   896   C CG2 . VAL A 1 190 ? 140.519 86.660  95.125  1.00 100.31 ? 190 VAL A CG2 1 
ATOM   897   N N   . HIS A 1 191 ? 140.932 84.872  99.629  1.00 100.19 ? 191 HIS A N   1 
ATOM   898   C CA  . HIS A 1 191 ? 140.518 84.700  101.027 1.00 97.99  ? 191 HIS A CA  1 
ATOM   899   C C   . HIS A 1 191 ? 141.679 84.546  102.023 1.00 100.82 ? 191 HIS A C   1 
ATOM   900   O O   . HIS A 1 191 ? 141.474 84.092  103.149 1.00 102.76 ? 191 HIS A O   1 
ATOM   901   C CB  . HIS A 1 191 ? 139.488 83.567  101.148 1.00 102.28 ? 191 HIS A CB  1 
ATOM   902   C CG  . HIS A 1 191 ? 138.251 83.775  100.313 1.00 105.24 ? 191 HIS A CG  1 
ATOM   903   N ND1 . HIS A 1 191 ? 138.065 83.355  99.020  1.00 105.96 ? 191 HIS A ND1 1 
ATOM   904   C CD2 . HIS A 1 191 ? 137.139 84.477  100.674 1.00 98.80  ? 191 HIS A CD2 1 
ATOM   905   C CE1 . HIS A 1 191 ? 136.858 83.771  98.614  1.00 103.63 ? 191 HIS A CE1 1 
ATOM   906   N NE2 . HIS A 1 191 ? 136.255 84.464  99.593  1.00 104.39 ? 191 HIS A NE2 1 
ATOM   907   N N   . LEU A 1 192 ? 142.901 84.929  101.651 1.00 104.66 ? 192 LEU A N   1 
ATOM   908   C CA  . LEU A 1 192 ? 144.053 84.969  102.561 1.00 99.15  ? 192 LEU A CA  1 
ATOM   909   C C   . LEU A 1 192 ? 143.850 86.012  103.662 1.00 98.29  ? 192 LEU A C   1 
ATOM   910   O O   . LEU A 1 192 ? 143.521 87.159  103.382 1.00 101.86 ? 192 LEU A O   1 
ATOM   911   C CB  . LEU A 1 192 ? 145.331 85.298  101.769 1.00 99.90  ? 192 LEU A CB  1 
ATOM   912   C CG  . LEU A 1 192 ? 145.740 84.215  100.771 1.00 103.85 ? 192 LEU A CG  1 
ATOM   913   C CD1 . LEU A 1 192 ? 146.874 84.722  99.892  1.00 105.74 ? 192 LEU A CD1 1 
ATOM   914   C CD2 . LEU A 1 192 ? 146.195 82.939  101.465 1.00 101.18 ? 192 LEU A CD2 1 
ATOM   915   N N   . ARG A 1 193 ? 144.098 85.650  104.920 1.00 86.62  ? 193 ARG A N   1 
ATOM   916   C CA  . ARG A 1 193 ? 143.922 86.544  106.069 1.00 87.74  ? 193 ARG A CA  1 
ATOM   917   C C   . ARG A 1 193 ? 145.252 87.120  106.546 1.00 88.41  ? 193 ARG A C   1 
ATOM   918   O O   . ARG A 1 193 ? 146.057 86.408  107.139 1.00 91.00  ? 193 ARG A O   1 
ATOM   919   C CB  . ARG A 1 193 ? 143.126 85.818  107.155 1.00 88.57  ? 193 ARG A CB  1 
ATOM   920   C CG  . ARG A 1 193 ? 141.635 85.760  106.865 1.00 91.53  ? 193 ARG A CG  1 
ATOM   921   C CD  . ARG A 1 193 ? 140.990 84.421  107.144 1.00 91.76  ? 193 ARG A CD  1 
ATOM   922   N NE  . ARG A 1 193 ? 141.054 84.065  108.550 1.00 98.65  ? 193 ARG A NE  1 
ATOM   923   C CZ  . ARG A 1 193 ? 140.185 83.266  109.153 1.00 97.01  ? 193 ARG A CZ  1 
ATOM   924   N NH1 . ARG A 1 193 ? 140.318 82.992  110.438 1.00 91.91  ? 193 ARG A NH1 1 
ATOM   925   N NH2 . ARG A 1 193 ? 139.174 82.759  108.472 1.00 95.13  ? 193 ARG A NH2 1 
ATOM   926   N N   . ALA A 1 194 ? 145.443 88.422  106.382 1.00 74.14  ? 194 ALA A N   1 
ATOM   927   C CA  . ALA A 1 194 ? 146.519 89.175  107.008 1.00 72.72  ? 194 ALA A CA  1 
ATOM   928   C C   . ALA A 1 194 ? 146.206 89.348  108.497 1.00 71.98  ? 194 ALA A C   1 
ATOM   929   O O   . ALA A 1 194 ? 145.475 90.249  108.874 1.00 75.09  ? 194 ALA A O   1 
ATOM   930   C CB  . ALA A 1 194 ? 146.641 90.510  106.277 1.00 76.24  ? 194 ALA A CB  1 
ATOM   931   N N   . CYS A 1 195 ? 146.704 88.445  109.341 1.00 78.08  ? 195 CYS A N   1 
ATOM   932   C CA  . CYS A 1 195 ? 146.209 88.228  110.704 1.00 79.85  ? 195 CYS A CA  1 
ATOM   933   C C   . CYS A 1 195 ? 147.235 88.473  111.818 1.00 85.23  ? 195 CYS A C   1 
ATOM   934   O O   . CYS A 1 195 ? 146.867 88.440  112.995 1.00 86.75  ? 195 CYS A O   1 
ATOM   935   C CB  . CYS A 1 195 ? 145.629 86.810  110.782 1.00 83.99  ? 195 CYS A CB  1 
ATOM   936   S SG  . CYS A 1 195 ? 146.811 85.551  110.223 1.00 87.60  ? 195 CYS A SG  1 
ATOM   937   N N   . GLY A 1 196 ? 148.503 88.731  111.488 1.00 85.43  ? 196 GLY A N   1 
ATOM   938   C CA  . GLY A 1 196 ? 149.540 89.094  112.454 1.00 79.17  ? 196 GLY A CA  1 
ATOM   939   C C   . GLY A 1 196 ? 149.259 90.397  113.202 1.00 78.37  ? 196 GLY A C   1 
ATOM   940   O O   . GLY A 1 196 ? 148.392 91.178  112.825 1.00 83.83  ? 196 GLY A O   1 
ATOM   941   N N   . ARG A 1 197 ? 149.937 90.641  114.322 1.00 76.60  ? 197 ARG A N   1 
ATOM   942   C CA  . ARG A 1 197 ? 149.608 91.768  115.248 1.00 77.20  ? 197 ARG A CA  1 
ATOM   943   C C   . ARG A 1 197 ? 149.553 93.151  114.620 1.00 79.26  ? 197 ARG A C   1 
ATOM   944   O O   . ARG A 1 197 ? 148.920 94.018  115.209 1.00 80.43  ? 197 ARG A O   1 
ATOM   945   C CB  . ARG A 1 197 ? 150.615 91.805  116.396 1.00 77.59  ? 197 ARG A CB  1 
ATOM   946   C CG  . ARG A 1 197 ? 150.191 92.649  117.587 1.00 81.56  ? 197 ARG A CG  1 
ATOM   947   C CD  . ARG A 1 197 ? 149.494 91.814  118.639 1.00 80.78  ? 197 ARG A CD  1 
ATOM   948   N NE  . ARG A 1 197 ? 148.087 92.161  118.746 1.00 87.10  ? 197 ARG A NE  1 
ATOM   949   C CZ  . ARG A 1 197 ? 147.577 92.929  119.698 1.00 88.84  ? 197 ARG A CZ  1 
ATOM   950   N NH1 . ARG A 1 197 ? 146.282 93.190  119.713 1.00 84.41  ? 197 ARG A NH1 1 
ATOM   951   N NH2 . ARG A 1 197 ? 148.363 93.433  120.631 1.00 82.27  ? 197 ARG A NH2 1 
ATOM   952   N N   . PHE A 1 198 ? 150.259 93.390  113.538 1.00 72.37  ? 198 PHE A N   1 
ATOM   953   C CA  . PHE A 1 198 ? 150.119 94.689  112.881 1.00 72.09  ? 198 PHE A CA  1 
ATOM   954   C C   . PHE A 1 198 ? 148.695 94.934  112.350 1.00 75.16  ? 198 PHE A C   1 
ATOM   955   O O   . PHE A 1 198 ? 148.222 96.063  112.325 1.00 75.17  ? 198 PHE A O   1 
ATOM   956   C CB  . PHE A 1 198 ? 151.151 94.773  111.756 1.00 68.52  ? 198 PHE A CB  1 
ATOM   957   C CG  . PHE A 1 198 ? 151.062 96.043  110.948 1.00 72.76  ? 198 PHE A CG  1 
ATOM   958   C CD1 . PHE A 1 198 ? 151.295 97.287  111.550 1.00 71.94  ? 198 PHE A CD1 1 
ATOM   959   C CD2 . PHE A 1 198 ? 150.720 95.985  109.592 1.00 73.86  ? 198 PHE A CD2 1 
ATOM   960   C CE1 . PHE A 1 198 ? 151.172 98.460  110.798 1.00 68.07  ? 198 PHE A CE1 1 
ATOM   961   C CE2 . PHE A 1 198 ? 150.583 97.159  108.841 1.00 67.66  ? 198 PHE A CE2 1 
ATOM   962   C CZ  . PHE A 1 198 ? 150.812 98.399  109.444 1.00 64.11  ? 198 PHE A CZ  1 
ATOM   963   N N   . PHE A 1 199 ? 147.989 93.875  111.956 1.00 65.23  ? 199 PHE A N   1 
ATOM   964   C CA  . PHE A 1 199 ? 146.654 93.929  111.366 1.00 59.33  ? 199 PHE A CA  1 
ATOM   965   C C   . PHE A 1 199 ? 145.519 93.742  112.370 1.00 68.95  ? 199 PHE A C   1 
ATOM   966   O O   . PHE A 1 199 ? 144.355 93.871  112.015 1.00 72.32  ? 199 PHE A O   1 
ATOM   967   C CB  . PHE A 1 199 ? 146.562 92.854  110.296 1.00 62.27  ? 199 PHE A CB  1 
ATOM   968   C CG  . PHE A 1 199 ? 147.680 92.925  109.293 1.00 65.12  ? 199 PHE A CG  1 
ATOM   969   C CD1 . PHE A 1 199 ? 147.777 94.022  108.428 1.00 67.91  ? 199 PHE A CD1 1 
ATOM   970   C CD2 . PHE A 1 199 ? 148.641 91.909  109.244 1.00 71.60  ? 199 PHE A CD2 1 
ATOM   971   C CE1 . PHE A 1 199 ? 148.793 94.072  107.465 1.00 68.32  ? 199 PHE A CE1 1 
ATOM   972   C CE2 . PHE A 1 199 ? 149.673 91.973  108.307 1.00 67.49  ? 199 PHE A CE2 1 
ATOM   973   C CZ  . PHE A 1 199 ? 149.744 93.046  107.408 1.00 67.67  ? 199 PHE A CZ  1 
ATOM   974   N N   . GLN A 1 200 ? 145.821 93.400  113.614 1.00 71.41  ? 200 GLN A N   1 
ATOM   975   C CA  . GLN A 1 200 ? 144.853 93.339  114.700 1.00 66.74  ? 200 GLN A CA  1 
ATOM   976   C C   . GLN A 1 200 ? 144.535 94.750  115.217 1.00 67.67  ? 200 GLN A C   1 
ATOM   977   O O   . GLN A 1 200 ? 145.279 95.689  114.955 1.00 77.83  ? 200 GLN A O   1 
ATOM   978   C CB  . GLN A 1 200 ? 145.406 92.416  115.790 1.00 72.76  ? 200 GLN A CB  1 
ATOM   979   C CG  . GLN A 1 200 ? 145.582 90.977  115.268 1.00 77.16  ? 200 GLN A CG  1 
ATOM   980   C CD  . GLN A 1 200 ? 146.258 90.052  116.266 1.00 76.01  ? 200 GLN A CD  1 
ATOM   981   O OE1 . GLN A 1 200 ? 146.411 90.346  117.441 1.00 70.44  ? 200 GLN A OE1 1 
ATOM   982   N NE2 . GLN A 1 200 ? 146.708 88.899  115.837 1.00 71.80  ? 200 GLN A NE2 1 
ATOM   983   N N   . LYS A 1 201 ? 143.444 94.927  115.971 1.00 70.75  ? 201 LYS A N   1 
ATOM   984   C CA  . LYS A 1 201 ? 143.077 96.226  116.552 1.00 74.95  ? 201 LYS A CA  1 
ATOM   985   C C   . LYS A 1 201 ? 143.583 96.324  117.998 1.00 84.47  ? 201 LYS A C   1 
ATOM   986   O O   . LYS A 1 201 ? 143.176 95.539  118.852 1.00 87.24  ? 201 LYS A O   1 
ATOM   987   C CB  . LYS A 1 201 ? 141.556 96.403  116.437 1.00 79.85  ? 201 LYS A CB  1 
ATOM   988   C CG  . LYS A 1 201 ? 141.106 97.825  116.787 1.00 81.24  ? 201 LYS A CG  1 
ATOM   989   C CD  . LYS A 1 201 ? 139.583 97.947  116.763 1.00 83.23  ? 201 LYS A CD  1 
ATOM   990   C CE  . LYS A 1 201 ? 139.154 99.333  117.253 1.00 82.05  ? 201 LYS A CE  1 
ATOM   991   N NZ  . LYS A 1 201 ? 137.727 99.372  117.653 1.00 81.40  ? 201 LYS A NZ  1 
ATOM   992   N N   . HIS A 1 202 ? 144.474 97.278  118.267 1.00 84.58  ? 202 HIS A N   1 
ATOM   993   C CA  . HIS A 1 202 ? 145.101 97.536  119.570 1.00 77.58  ? 202 HIS A CA  1 
ATOM   994   C C   . HIS A 1 202 ? 145.617 98.977  119.678 1.00 79.35  ? 202 HIS A C   1 
ATOM   995   O O   . HIS A 1 202 ? 145.562 99.743  118.720 1.00 80.60  ? 202 HIS A O   1 
ATOM   996   C CB  . HIS A 1 202 ? 146.199 96.500  119.841 1.00 78.58  ? 202 HIS A CB  1 
ATOM   997   C CG  . HIS A 1 202 ? 147.352 96.503  118.878 1.00 82.19  ? 202 HIS A CG  1 
ATOM   998   N ND1 . HIS A 1 202 ? 148.450 97.363  118.915 1.00 84.61  ? 202 HIS A ND1 1 
ATOM   999   C CD2 . HIS A 1 202 ? 147.537 95.598  117.883 1.00 83.00  ? 202 HIS A CD2 1 
ATOM   1000  C CE1 . HIS A 1 202 ? 149.268 96.954  117.932 1.00 82.23  ? 202 HIS A CE1 1 
ATOM   1001  N NE2 . HIS A 1 202 ? 148.737 95.898  117.299 1.00 78.62  ? 202 HIS A NE2 1 
ATOM   1002  N N   . GLN A 1 203 ? 146.057 99.385  120.870 1.00 94.84  ? 203 GLN A N   1 
ATOM   1003  C CA  . GLN A 1 203 ? 146.482 100.755 121.170 1.00 98.01  ? 203 GLN A CA  1 
ATOM   1004  C C   . GLN A 1 203 ? 147.837 101.188 120.581 1.00 97.49  ? 203 GLN A C   1 
ATOM   1005  O O   . GLN A 1 203 ? 148.182 102.369 120.656 1.00 97.24  ? 203 GLN A O   1 
ATOM   1006  C CB  . GLN A 1 203 ? 146.515 100.894 122.690 1.00 91.59  ? 203 GLN A CB  1 
ATOM   1007  N N   . GLY A 1 204 ? 148.631 100.268 120.030 1.00 84.46  ? 204 GLY A N   1 
ATOM   1008  C CA  . GLY A 1 204 ? 149.937 100.532 119.422 1.00 84.08  ? 204 GLY A CA  1 
ATOM   1009  C C   . GLY A 1 204 ? 149.875 100.927 117.944 1.00 86.42  ? 204 GLY A C   1 
ATOM   1010  O O   . GLY A 1 204 ? 148.838 101.342 117.427 1.00 81.78  ? 204 GLY A O   1 
ATOM   1011  N N   . THR A 1 205 ? 150.991 100.723 117.247 1.00 87.90  ? 205 THR A N   1 
ATOM   1012  C CA  . THR A 1 205 ? 151.072 100.845 115.786 1.00 83.43  ? 205 THR A CA  1 
ATOM   1013  C C   . THR A 1 205 ? 150.387 99.655  115.124 1.00 87.97  ? 205 THR A C   1 
ATOM   1014  O O   . THR A 1 205 ? 150.878 98.531  115.193 1.00 85.36  ? 205 THR A O   1 
ATOM   1015  C CB  . THR A 1 205 ? 152.528 100.960 115.324 1.00 82.29  ? 205 THR A CB  1 
ATOM   1016  O OG1 . THR A 1 205 ? 153.099 102.113 115.884 1.00 82.33  ? 205 THR A OG1 1 
ATOM   1017  C CG2 . THR A 1 205 ? 152.662 101.106 113.818 1.00 81.23  ? 205 THR A CG2 1 
ATOM   1018  N N   . CYS A 1 206 ? 149.254 99.899  114.476 1.00 82.96  ? 206 CYS A N   1 
ATOM   1019  C CA  . CYS A 1 206 ? 148.471 98.894  113.768 1.00 74.51  ? 206 CYS A CA  1 
ATOM   1020  C C   . CYS A 1 206 ? 147.623 99.524  112.668 1.00 74.86  ? 206 CYS A C   1 
ATOM   1021  O O   . CYS A 1 206 ? 147.414 100.735 112.618 1.00 77.02  ? 206 CYS A O   1 
ATOM   1022  C CB  . CYS A 1 206 ? 147.576 98.125  114.749 1.00 71.17  ? 206 CYS A CB  1 
ATOM   1023  S SG  . CYS A 1 206 ? 146.214 99.140  115.370 1.00 62.37  ? 206 CYS A SG  1 
ATOM   1024  N N   . PHE A 1 207 ? 147.091 98.672  111.789 1.00 60.97  ? 207 PHE A N   1 
ATOM   1025  C CA  . PHE A 1 207 ? 146.137 99.001  110.729 1.00 47.18  ? 207 PHE A CA  1 
ATOM   1026  C C   . PHE A 1 207 ? 145.129 97.864  110.570 1.00 59.77  ? 207 PHE A C   1 
ATOM   1027  O O   . PHE A 1 207 ? 145.345 96.935  109.799 1.00 71.41  ? 207 PHE A O   1 
ATOM   1028  C CB  . PHE A 1 207 ? 146.894 99.279  109.425 1.00 55.46  ? 207 PHE A CB  1 
ATOM   1029  C CG  . PHE A 1 207 ? 146.051 99.483  108.173 1.00 60.39  ? 207 PHE A CG  1 
ATOM   1030  C CD1 . PHE A 1 207 ? 144.940 100.343 108.167 1.00 62.12  ? 207 PHE A CD1 1 
ATOM   1031  C CD2 . PHE A 1 207 ? 146.421 98.839  106.986 1.00 63.13  ? 207 PHE A CD2 1 
ATOM   1032  C CE1 . PHE A 1 207 ? 144.226 100.569 106.980 1.00 58.47  ? 207 PHE A CE1 1 
ATOM   1033  C CE2 . PHE A 1 207 ? 145.715 99.071  105.794 1.00 59.27  ? 207 PHE A CE2 1 
ATOM   1034  C CZ  . PHE A 1 207 ? 144.617 99.937  105.792 1.00 58.81  ? 207 PHE A CZ  1 
ATOM   1035  N N   . TYR A 1 208 ? 144.029 97.911  111.318 1.00 68.57  ? 208 TYR A N   1 
ATOM   1036  C CA  . TYR A 1 208 ? 142.910 96.989  111.143 1.00 66.68  ? 208 TYR A CA  1 
ATOM   1037  C C   . TYR A 1 208 ? 142.071 97.387  109.922 1.00 76.81  ? 208 TYR A C   1 
ATOM   1038  O O   . TYR A 1 208 ? 141.616 98.522  109.819 1.00 80.21  ? 208 TYR A O   1 
ATOM   1039  C CB  . TYR A 1 208 ? 142.065 96.945  112.422 1.00 63.93  ? 208 TYR A CB  1 
ATOM   1040  C CG  . TYR A 1 208 ? 140.913 95.963  112.362 1.00 67.40  ? 208 TYR A CG  1 
ATOM   1041  C CD1 . TYR A 1 208 ? 141.143 94.596  112.596 1.00 70.41  ? 208 TYR A CD1 1 
ATOM   1042  C CD2 . TYR A 1 208 ? 139.619 96.402  112.028 1.00 71.99  ? 208 TYR A CD2 1 
ATOM   1043  C CE1 . TYR A 1 208 ? 140.103 93.662  112.463 1.00 61.66  ? 208 TYR A CE1 1 
ATOM   1044  C CE2 . TYR A 1 208 ? 138.575 95.472  111.893 1.00 72.05  ? 208 TYR A CE2 1 
ATOM   1045  C CZ  . TYR A 1 208 ? 138.819 94.101  112.096 1.00 67.56  ? 208 TYR A CZ  1 
ATOM   1046  O OH  . TYR A 1 208 ? 137.822 93.207  111.904 1.00 76.90  ? 208 TYR A OH  1 
ATOM   1047  N N   . PHE A 1 209 ? 141.827 96.443  109.015 1.00 67.38  ? 209 PHE A N   1 
ATOM   1048  C CA  . PHE A 1 209 ? 140.977 96.588  107.830 1.00 60.55  ? 209 PHE A CA  1 
ATOM   1049  C C   . PHE A 1 209 ? 140.022 95.399  107.690 1.00 65.32  ? 209 PHE A C   1 
ATOM   1050  O O   . PHE A 1 209 ? 139.554 95.090  106.598 1.00 80.10  ? 209 PHE A O   1 
ATOM   1051  C CB  . PHE A 1 209 ? 141.847 96.811  106.587 1.00 64.60  ? 209 PHE A CB  1 
ATOM   1052  C CG  . PHE A 1 209 ? 142.896 95.752  106.316 1.00 61.99  ? 209 PHE A CG  1 
ATOM   1053  C CD1 . PHE A 1 209 ? 142.566 94.524  105.719 1.00 65.75  ? 209 PHE A CD1 1 
ATOM   1054  C CD2 . PHE A 1 209 ? 144.233 96.016  106.637 1.00 60.83  ? 209 PHE A CD2 1 
ATOM   1055  C CE1 . PHE A 1 209 ? 143.561 93.574  105.443 1.00 64.16  ? 209 PHE A CE1 1 
ATOM   1056  C CE2 . PHE A 1 209 ? 145.230 95.088  106.326 1.00 68.56  ? 209 PHE A CE2 1 
ATOM   1057  C CZ  . PHE A 1 209 ? 144.897 93.864  105.734 1.00 66.38  ? 209 PHE A CZ  1 
ATOM   1058  N N   . GLY A 1 210 ? 139.738 94.686  108.774 1.00 65.64  ? 210 GLY A N   1 
ATOM   1059  C CA  . GLY A 1 210 ? 139.398 93.270  108.681 1.00 63.66  ? 210 GLY A CA  1 
ATOM   1060  C C   . GLY A 1 210 ? 140.708 92.500  108.504 1.00 75.75  ? 210 GLY A C   1 
ATOM   1061  O O   . GLY A 1 210 ? 141.754 92.963  108.952 1.00 85.30  ? 210 GLY A O   1 
ATOM   1062  N N   . GLU A 1 211 ? 140.701 91.368  107.807 1.00 73.21  ? 211 GLU A N   1 
ATOM   1063  C CA  . GLU A 1 211 ? 141.947 90.661  107.445 1.00 73.08  ? 211 GLU A CA  1 
ATOM   1064  C C   . GLU A 1 211 ? 142.019 90.246  105.974 1.00 76.25  ? 211 GLU A C   1 
ATOM   1065  O O   . GLU A 1 211 ? 143.052 89.781  105.504 1.00 89.32  ? 211 GLU A O   1 
ATOM   1066  C CB  . GLU A 1 211 ? 142.133 89.432  108.338 1.00 76.05  ? 211 GLU A CB  1 
ATOM   1067  C CG  . GLU A 1 211 ? 142.324 89.790  109.817 1.00 75.41  ? 211 GLU A CG  1 
ATOM   1068  C CD  . GLU A 1 211 ? 142.390 88.563  110.732 1.00 85.16  ? 211 GLU A CD  1 
ATOM   1069  O OE1 . GLU A 1 211 ? 142.164 87.407  110.289 1.00 82.67  ? 211 GLU A OE1 1 
ATOM   1070  O OE2 . GLU A 1 211 ? 142.593 88.770  111.945 1.00 85.92  ? 211 GLU A OE2 1 
ATOM   1071  N N   . LEU A 1 212 ? 140.928 90.384  105.232 1.00 70.83  ? 212 LEU A N   1 
ATOM   1072  C CA  . LEU A 1 212 ? 140.771 89.833  103.889 1.00 74.21  ? 212 LEU A CA  1 
ATOM   1073  C C   . LEU A 1 212 ? 141.010 90.899  102.815 1.00 71.56  ? 212 LEU A C   1 
ATOM   1074  O O   . LEU A 1 212 ? 140.699 92.068  103.046 1.00 71.84  ? 212 LEU A O   1 
ATOM   1075  C CB  . LEU A 1 212 ? 139.360 89.244  103.758 1.00 79.35  ? 212 LEU A CB  1 
ATOM   1076  C CG  . LEU A 1 212 ? 139.062 88.069  104.700 1.00 74.74  ? 212 LEU A CG  1 
ATOM   1077  C CD1 . LEU A 1 212 ? 137.563 87.904  104.842 1.00 74.50  ? 212 LEU A CD1 1 
ATOM   1078  C CD2 . LEU A 1 212 ? 139.631 86.772  104.157 1.00 72.20  ? 212 LEU A CD2 1 
ATOM   1079  N N   . PRO A 1 213 ? 141.458 90.509  101.612 1.00 76.65  ? 213 PRO A N   1 
ATOM   1080  C CA  . PRO A 1 213 ? 141.508 91.362  100.430 1.00 82.91  ? 213 PRO A CA  1 
ATOM   1081  C C   . PRO A 1 213 ? 140.235 92.175  100.172 1.00 82.76  ? 213 PRO A C   1 
ATOM   1082  O O   . PRO A 1 213 ? 140.319 93.375  99.943  1.00 83.45  ? 213 PRO A O   1 
ATOM   1083  C CB  . PRO A 1 213 ? 141.801 90.394  99.283  1.00 82.79  ? 213 PRO A CB  1 
ATOM   1084  C CG  . PRO A 1 213 ? 142.700 89.362  99.938  1.00 78.44  ? 213 PRO A CG  1 
ATOM   1085  C CD  . PRO A 1 213 ? 142.070 89.228  101.315 1.00 77.28  ? 213 PRO A CD  1 
ATOM   1086  N N   . LEU A 1 214 ? 139.039 91.584  100.264 1.00 78.27  ? 214 LEU A N   1 
ATOM   1087  C CA  . LEU A 1 214 ? 137.789 92.324  100.055 1.00 79.43  ? 214 LEU A CA  1 
ATOM   1088  C C   . LEU A 1 214 ? 137.553 93.407  101.118 1.00 80.30  ? 214 LEU A C   1 
ATOM   1089  O O   . LEU A 1 214 ? 137.124 94.513  100.796 1.00 84.17  ? 214 LEU A O   1 
ATOM   1090  C CB  . LEU A 1 214 ? 136.616 91.335  99.994  1.00 77.12  ? 214 LEU A CB  1 
ATOM   1091  C CG  . LEU A 1 214 ? 135.245 92.013  99.810  1.00 79.96  ? 214 LEU A CG  1 
ATOM   1092  C CD1 . LEU A 1 214 ? 135.138 92.757  98.487  1.00 78.42  ? 214 LEU A CD1 1 
ATOM   1093  C CD2 . LEU A 1 214 ? 134.135 90.978  99.879  1.00 85.25  ? 214 LEU A CD2 1 
ATOM   1094  N N   . SER A 1 215 ? 137.859 93.117  102.380 1.00 63.13  ? 215 SER A N   1 
ATOM   1095  C CA  . SER A 1 215 ? 137.724 94.092  103.460 1.00 56.65  ? 215 SER A CA  1 
ATOM   1096  C C   . SER A 1 215 ? 138.759 95.210  103.354 1.00 65.11  ? 215 SER A C   1 
ATOM   1097  O O   . SER A 1 215 ? 138.427 96.369  103.576 1.00 69.89  ? 215 SER A O   1 
ATOM   1098  C CB  . SER A 1 215 ? 137.813 93.413  104.819 1.00 61.77  ? 215 SER A CB  1 
ATOM   1099  O OG  . SER A 1 215 ? 136.983 92.268  104.854 1.00 66.05  ? 215 SER A OG  1 
ATOM   1100  N N   . LEU A 1 216 ? 139.985 94.917  102.914 1.00 72.30  ? 216 LEU A N   1 
ATOM   1101  C CA  . LEU A 1 216 ? 140.987 95.931  102.591 1.00 70.80  ? 216 LEU A CA  1 
ATOM   1102  C C   . LEU A 1 216 ? 140.521 96.849  101.460 1.00 70.71  ? 216 LEU A C   1 
ATOM   1103  O O   . LEU A 1 216 ? 140.596 98.068  101.584 1.00 76.10  ? 216 LEU A O   1 
ATOM   1104  C CB  . LEU A 1 216 ? 142.309 95.231  102.242 1.00 68.23  ? 216 LEU A CB  1 
ATOM   1105  C CG  . LEU A 1 216 ? 143.475 96.169  101.901 1.00 62.23  ? 216 LEU A CG  1 
ATOM   1106  C CD1 . LEU A 1 216 ? 143.814 97.190  102.977 1.00 65.90  ? 216 LEU A CD1 1 
ATOM   1107  C CD2 . LEU A 1 216 ? 144.713 95.325  101.666 1.00 65.56  ? 216 LEU A CD2 1 
ATOM   1108  N N   . ALA A 1 217 ? 140.005 96.295  100.364 1.00 65.83  ? 217 ALA A N   1 
ATOM   1109  C CA  . ALA A 1 217 ? 139.508 97.070  99.234  1.00 56.94  ? 217 ALA A CA  1 
ATOM   1110  C C   . ALA A 1 217 ? 138.337 97.989  99.622  1.00 65.96  ? 217 ALA A C   1 
ATOM   1111  O O   . ALA A 1 217 ? 138.294 99.145  99.214  1.00 67.55  ? 217 ALA A O   1 
ATOM   1112  C CB  . ALA A 1 217 ? 139.130 96.092  98.122  1.00 59.69  ? 217 ALA A CB  1 
ATOM   1113  N N   . ALA A 1 218 ? 137.421 97.520  100.470 1.00 76.50  ? 218 ALA A N   1 
ATOM   1114  C CA  . ALA A 1 218 ? 136.346 98.337  101.023 1.00 66.26  ? 218 ALA A CA  1 
ATOM   1115  C C   . ALA A 1 218 ? 136.871 99.457  101.938 1.00 65.51  ? 218 ALA A C   1 
ATOM   1116  O O   . ALA A 1 218 ? 136.511 100.617 101.772 1.00 68.17  ? 218 ALA A O   1 
ATOM   1117  C CB  . ALA A 1 218 ? 135.378 97.409  101.758 1.00 58.56  ? 218 ALA A CB  1 
ATOM   1118  N N   . CYS A 1 219 ? 137.767 99.165  102.877 1.00 79.47  ? 219 CYS A N   1 
ATOM   1119  C CA  . CYS A 1 219 ? 138.253 100.162 103.834 1.00 81.32  ? 219 CYS A CA  1 
ATOM   1120  C C   . CYS A 1 219 ? 139.173 101.227 103.206 1.00 78.10  ? 219 CYS A C   1 
ATOM   1121  O O   . CYS A 1 219 ? 139.165 102.381 103.621 1.00 71.56  ? 219 CYS A O   1 
ATOM   1122  C CB  . CYS A 1 219 ? 138.916 99.425  104.996 1.00 79.96  ? 219 CYS A CB  1 
ATOM   1123  S SG  . CYS A 1 219 ? 137.677 98.353  105.771 1.00 86.37  ? 219 CYS A SG  1 
ATOM   1124  N N   . THR A 1 220 ? 139.907 100.871 102.151 1.00 82.77  ? 220 THR A N   1 
ATOM   1125  C CA  . THR A 1 220 ? 140.663 101.795 101.285 1.00 79.27  ? 220 THR A CA  1 
ATOM   1126  C C   . THR A 1 220 ? 139.799 102.473 100.205 1.00 81.98  ? 220 THR A C   1 
ATOM   1127  O O   . THR A 1 220 ? 140.321 103.254 99.412  1.00 87.06  ? 220 THR A O   1 
ATOM   1128  C CB  . THR A 1 220 ? 141.849 101.084 100.629 1.00 78.29  ? 220 THR A CB  1 
ATOM   1129  O OG1 . THR A 1 220 ? 141.408 99.980  99.893  1.00 86.61  ? 220 THR A OG1 1 
ATOM   1130  C CG2 . THR A 1 220 ? 142.876 100.548 101.610 1.00 75.83  ? 220 THR A CG2 1 
ATOM   1131  N N   . LYS A 1 221 ? 138.479 102.243 100.185 1.00 81.99  ? 221 LYS A N   1 
ATOM   1132  C CA  . LYS A 1 221 ? 137.478 102.938 99.353  1.00 77.90  ? 221 LYS A CA  1 
ATOM   1133  C C   . LYS A 1 221 ? 137.609 102.710 97.848  1.00 82.40  ? 221 LYS A C   1 
ATOM   1134  O O   . LYS A 1 221 ? 137.474 103.640 97.059  1.00 82.24  ? 221 LYS A O   1 
ATOM   1135  C CB  . LYS A 1 221 ? 137.380 104.430 99.720  1.00 75.26  ? 221 LYS A CB  1 
ATOM   1136  C CG  . LYS A 1 221 ? 137.379 104.690 101.230 1.00 85.62  ? 221 LYS A CG  1 
ATOM   1137  C CD  . LYS A 1 221 ? 137.045 106.152 101.534 1.00 88.13  ? 221 LYS A CD  1 
ATOM   1138  C CE  . LYS A 1 221 ? 137.435 106.574 102.954 1.00 85.75  ? 221 LYS A CE  1 
ATOM   1139  N NZ  . LYS A 1 221 ? 136.926 105.667 104.014 1.00 78.73  ? 221 LYS A NZ  1 
ATOM   1140  N N   . GLN A 1 222 ? 137.905 101.483 97.429  1.00 89.99  ? 222 GLN A N   1 
ATOM   1141  C CA  . GLN A 1 222 ? 138.179 101.138 96.032  1.00 88.80  ? 222 GLN A CA  1 
ATOM   1142  C C   . GLN A 1 222 ? 137.014 100.390 95.378  1.00 83.80  ? 222 GLN A C   1 
ATOM   1143  O O   . GLN A 1 222 ? 137.018 99.166  95.317  1.00 82.58  ? 222 GLN A O   1 
ATOM   1144  C CB  . GLN A 1 222 ? 139.474 100.326 95.959  1.00 87.15  ? 222 GLN A CB  1 
ATOM   1145  C CG  . GLN A 1 222 ? 140.667 101.133 96.459  1.00 83.35  ? 222 GLN A CG  1 
ATOM   1146  C CD  . GLN A 1 222 ? 141.954 100.372 96.250  1.00 84.88  ? 222 GLN A CD  1 
ATOM   1147  O OE1 . GLN A 1 222 ? 142.441 100.231 95.145  1.00 93.37  ? 222 GLN A OE1 1 
ATOM   1148  N NE2 . GLN A 1 222 ? 142.548 99.862  97.298  1.00 84.40  ? 222 GLN A NE2 1 
ATOM   1149  N N   . TRP A 1 223 ? 136.017 101.100 94.886  1.00 88.66  ? 223 TRP A N   1 
ATOM   1150  C CA  . TRP A 1 223 ? 134.886 100.326 94.336  1.00 96.10  ? 223 TRP A CA  1 
ATOM   1151  C C   . TRP A 1 223 ? 135.383 99.401  93.221  1.00 100.91 ? 223 TRP A C   1 
ATOM   1152  O O   . TRP A 1 223 ? 135.076 98.215  93.294  1.00 104.35 ? 223 TRP A O   1 
ATOM   1153  C CB  . TRP A 1 223 ? 133.771 101.263 93.876  1.00 95.88  ? 223 TRP A CB  1 
ATOM   1154  C CG  . TRP A 1 223 ? 132.903 101.747 94.992  1.00 101.37 ? 223 TRP A CG  1 
ATOM   1155  C CD1 . TRP A 1 223 ? 132.860 103.004 95.520  1.00 99.58  ? 223 TRP A CD1 1 
ATOM   1156  C CD2 . TRP A 1 223 ? 131.945 100.970 95.728  1.00 101.45 ? 223 TRP A CD2 1 
ATOM   1157  N NE1 . TRP A 1 223 ? 131.939 103.065 96.531  1.00 95.37  ? 223 TRP A NE1 1 
ATOM   1158  C CE2 . TRP A 1 223 ? 131.363 101.831 96.681  1.00 100.80 ? 223 TRP A CE2 1 
ATOM   1159  C CE3 . TRP A 1 223 ? 131.524 99.639  95.672  1.00 92.48  ? 223 TRP A CE3 1 
ATOM   1160  C CZ2 . TRP A 1 223 ? 130.381 101.400 97.567  1.00 100.23 ? 223 TRP A CZ2 1 
ATOM   1161  C CZ3 . TRP A 1 223 ? 130.559 99.216  96.554  1.00 89.91  ? 223 TRP A CZ3 1 
ATOM   1162  C CH2 . TRP A 1 223 ? 129.999 100.083 97.487  1.00 97.43  ? 223 TRP A CH2 1 
ATOM   1163  N N   . ASP A 1 224 ? 136.133 99.901  92.240  1.00 102.49 ? 224 ASP A N   1 
ATOM   1164  C CA  . ASP A 1 224 ? 136.538 99.089  91.094  1.00 98.87  ? 224 ASP A CA  1 
ATOM   1165  C C   . ASP A 1 224 ? 137.240 97.792  91.522  1.00 100.19 ? 224 ASP A C   1 
ATOM   1166  O O   . ASP A 1 224 ? 136.927 96.726  90.996  1.00 98.08  ? 224 ASP A O   1 
ATOM   1167  C CB  . ASP A 1 224 ? 137.394 99.921  90.125  1.00 101.23 ? 224 ASP A CB  1 
ATOM   1168  C CG  . ASP A 1 224 ? 138.598 100.667 90.724  1.00 102.97 ? 224 ASP A CG  1 
ATOM   1169  O OD1 . ASP A 1 224 ? 138.789 100.649 91.958  1.00 101.21 ? 224 ASP A OD1 1 
ATOM   1170  O OD2 . ASP A 1 224 ? 139.332 101.305 89.943  1.00 105.91 ? 224 ASP A OD2 1 
ATOM   1171  N N   . VAL A 1 225 ? 138.122 97.850  92.519  1.00 97.07  ? 225 VAL A N   1 
ATOM   1172  C CA  . VAL A 1 225 ? 138.739 96.658  93.119  1.00 94.41  ? 225 VAL A CA  1 
ATOM   1173  C C   . VAL A 1 225 ? 137.709 95.824  93.875  1.00 93.37  ? 225 VAL A C   1 
ATOM   1174  O O   . VAL A 1 225 ? 137.698 94.610  93.717  1.00 98.40  ? 225 VAL A O   1 
ATOM   1175  C CB  . VAL A 1 225 ? 139.926 97.020  94.027  1.00 95.55  ? 225 VAL A CB  1 
ATOM   1176  C CG1 . VAL A 1 225 ? 140.566 95.778  94.644  1.00 94.92  ? 225 VAL A CG1 1 
ATOM   1177  C CG2 . VAL A 1 225 ? 141.024 97.744  93.247  1.00 91.91  ? 225 VAL A CG2 1 
ATOM   1178  N N   . VAL A 1 226 ? 136.805 96.432  94.648  1.00 89.11  ? 226 VAL A N   1 
ATOM   1179  C CA  . VAL A 1 226 ? 135.715 95.723  95.347  1.00 91.23  ? 226 VAL A CA  1 
ATOM   1180  C C   . VAL A 1 226 ? 134.819 94.997  94.351  1.00 93.98  ? 226 VAL A C   1 
ATOM   1181  O O   . VAL A 1 226 ? 134.561 93.813  94.520  1.00 93.45  ? 226 VAL A O   1 
ATOM   1182  C CB  . VAL A 1 226 ? 134.890 96.694  96.211  1.00 90.72  ? 226 VAL A CB  1 
ATOM   1183  C CG1 . VAL A 1 226 ? 133.540 96.135  96.655  1.00 91.00  ? 226 VAL A CG1 1 
ATOM   1184  C CG2 . VAL A 1 226 ? 135.662 97.058  97.477  1.00 94.22  ? 226 VAL A CG2 1 
ATOM   1185  N N   . THR A 1 227 ? 134.404 95.671  93.278  1.00 102.83 ? 227 THR A N   1 
ATOM   1186  C CA  . THR A 1 227 ? 133.632 95.056  92.197  1.00 98.87  ? 227 THR A CA  1 
ATOM   1187  C C   . THR A 1 227 ? 134.413 93.906  91.567  1.00 96.43  ? 227 THR A C   1 
ATOM   1188  O O   . THR A 1 227 ? 133.883 92.811  91.421  1.00 95.56  ? 227 THR A O   1 
ATOM   1189  C CB  . THR A 1 227 ? 133.275 96.087  91.117  1.00 95.88  ? 227 THR A CB  1 
ATOM   1190  O OG1 . THR A 1 227 ? 132.561 97.161  91.677  1.00 95.91  ? 227 THR A OG1 1 
ATOM   1191  C CG2 . THR A 1 227 ? 132.412 95.496  90.011  1.00 93.62  ? 227 THR A CG2 1 
ATOM   1192  N N   . TYR A 1 228 ? 135.692 94.100  91.237  1.00 97.65  ? 228 TYR A N   1 
ATOM   1193  C CA  . TYR A 1 228 ? 136.486 93.033  90.643  1.00 98.45  ? 228 TYR A CA  1 
ATOM   1194  C C   . TYR A 1 228 ? 136.622 91.827  91.583  1.00 100.56 ? 228 TYR A C   1 
ATOM   1195  O O   . TYR A 1 228 ? 136.315 90.700  91.201  1.00 103.20 ? 228 TYR A O   1 
ATOM   1196  C CB  . TYR A 1 228 ? 137.845 93.575  90.204  1.00 98.98  ? 228 TYR A CB  1 
ATOM   1197  C CG  . TYR A 1 228 ? 138.638 92.510  89.489  1.00 99.66  ? 228 TYR A CG  1 
ATOM   1198  C CD1 . TYR A 1 228 ? 138.303 92.179  88.164  1.00 99.87  ? 228 TYR A CD1 1 
ATOM   1199  C CD2 . TYR A 1 228 ? 139.586 91.746  90.188  1.00 96.13  ? 228 TYR A CD2 1 
ATOM   1200  C CE1 . TYR A 1 228 ? 138.895 91.069  87.543  1.00 98.83  ? 228 TYR A CE1 1 
ATOM   1201  C CE2 . TYR A 1 228 ? 140.179 90.633  89.571  1.00 100.68 ? 228 TYR A CE2 1 
ATOM   1202  C CZ  . TYR A 1 228 ? 139.831 90.289  88.252  1.00 102.77 ? 228 TYR A CZ  1 
ATOM   1203  O OH  . TYR A 1 228 ? 140.394 89.208  87.660  1.00 102.45 ? 228 TYR A OH  1 
ATOM   1204  N N   . LEU A 1 229 ? 137.011 92.033  92.840  1.00 95.55  ? 229 LEU A N   1 
ATOM   1205  C CA  . LEU A 1 229 ? 137.128 90.941  93.802  1.00 95.14  ? 229 LEU A CA  1 
ATOM   1206  C C   . LEU A 1 229 ? 135.796 90.208  93.976  1.00 97.35  ? 229 LEU A C   1 
ATOM   1207  O O   . LEU A 1 229 ? 135.798 88.983  93.994  1.00 94.28  ? 229 LEU A O   1 
ATOM   1208  C CB  . LEU A 1 229 ? 137.651 91.477  95.143  1.00 94.99  ? 229 LEU A CB  1 
ATOM   1209  C CG  . LEU A 1 229 ? 139.122 91.917  95.134  1.00 90.89  ? 229 LEU A CG  1 
ATOM   1210  C CD1 . LEU A 1 229 ? 139.452 92.532  96.484  1.00 90.30  ? 229 LEU A CD1 1 
ATOM   1211  C CD2 . LEU A 1 229 ? 140.089 90.764  94.903  1.00 90.27  ? 229 LEU A CD2 1 
ATOM   1212  N N   . LEU A 1 230 ? 134.663 90.914  94.046  1.00 100.46 ? 230 LEU A N   1 
ATOM   1213  C CA  . LEU A 1 230 ? 133.339 90.308  94.217  1.00 95.50  ? 230 LEU A CA  1 
ATOM   1214  C C   . LEU A 1 230 ? 132.834 89.509  93.016  1.00 96.09  ? 230 LEU A C   1 
ATOM   1215  O O   . LEU A 1 230 ? 132.173 88.495  93.221  1.00 91.65  ? 230 LEU A O   1 
ATOM   1216  C CB  . LEU A 1 230 ? 132.311 91.403  94.526  1.00 91.60  ? 230 LEU A CB  1 
ATOM   1217  C CG  . LEU A 1 230 ? 132.343 91.904  95.970  1.00 90.37  ? 230 LEU A CG  1 
ATOM   1218  C CD1 . LEU A 1 230 ? 131.361 93.057  96.142  1.00 93.64  ? 230 LEU A CD1 1 
ATOM   1219  C CD2 . LEU A 1 230 ? 131.933 90.822  96.952  1.00 89.07  ? 230 LEU A CD2 1 
ATOM   1220  N N   . GLU A 1 231 ? 133.090 89.946  91.779  1.00 109.66 ? 231 GLU A N   1 
ATOM   1221  C CA  . GLU A 1 231 ? 132.447 89.361  90.591  1.00 107.89 ? 231 GLU A CA  1 
ATOM   1222  C C   . GLU A 1 231 ? 133.384 89.023  89.409  1.00 108.07 ? 231 GLU A C   1 
ATOM   1223  O O   . GLU A 1 231 ? 132.920 88.815  88.291  1.00 112.19 ? 231 GLU A O   1 
ATOM   1224  C CB  . GLU A 1 231 ? 131.163 90.141  90.228  1.00 108.80 ? 231 GLU A CB  1 
ATOM   1225  C CG  . GLU A 1 231 ? 131.343 91.641  89.974  1.00 108.57 ? 231 GLU A CG  1 
ATOM   1226  C CD  . GLU A 1 231 ? 130.062 92.297  89.436  1.00 110.65 ? 231 GLU A CD  1 
ATOM   1227  O OE1 . GLU A 1 231 ? 129.018 92.290  90.130  1.00 110.74 ? 231 GLU A OE1 1 
ATOM   1228  O OE2 . GLU A 1 231 ? 130.098 92.845  88.311  1.00 108.37 ? 231 GLU A OE2 1 
ATOM   1229  N N   . ASN A 1 232 ? 134.694 88.880  89.636  1.00 108.03 ? 232 ASN A N   1 
ATOM   1230  C CA  . ASN A 1 232 ? 135.591 88.203  88.690  1.00 110.37 ? 232 ASN A CA  1 
ATOM   1231  C C   . ASN A 1 232 ? 135.245 86.700  88.536  1.00 113.30 ? 232 ASN A C   1 
ATOM   1232  O O   . ASN A 1 232 ? 134.733 86.088  89.478  1.00 113.21 ? 232 ASN A O   1 
ATOM   1233  C CB  . ASN A 1 232 ? 137.062 88.387  89.110  1.00 111.34 ? 232 ASN A CB  1 
ATOM   1234  C CG  . ASN A 1 232 ? 137.469 87.497  90.271  1.00 108.53 ? 232 ASN A CG  1 
ATOM   1235  O OD1 . ASN A 1 232 ? 137.892 86.371  90.074  1.00 107.48 ? 232 ASN A OD1 1 
ATOM   1236  N ND2 . ASN A 1 232 ? 137.345 87.953  91.488  1.00 107.06 ? 232 ASN A ND2 1 
ATOM   1237  N N   . PRO A 1 233 ? 135.542 86.066  87.385  1.00 117.97 ? 233 PRO A N   1 
ATOM   1238  C CA  . PRO A 1 233 ? 135.221 84.657  87.146  1.00 117.40 ? 233 PRO A CA  1 
ATOM   1239  C C   . PRO A 1 233 ? 136.234 83.656  87.733  1.00 117.22 ? 233 PRO A C   1 
ATOM   1240  O O   . PRO A 1 233 ? 135.962 82.456  87.734  1.00 115.05 ? 233 PRO A O   1 
ATOM   1241  C CB  . PRO A 1 233 ? 135.162 84.543  85.622  1.00 114.29 ? 233 PRO A CB  1 
ATOM   1242  C CG  . PRO A 1 233 ? 136.205 85.553  85.159  1.00 114.59 ? 233 PRO A CG  1 
ATOM   1243  C CD  . PRO A 1 233 ? 136.039 86.687  86.167  1.00 114.98 ? 233 PRO A CD  1 
ATOM   1244  N N   . HIS A 1 234 ? 137.407 84.104  88.189  1.00 118.20 ? 234 HIS A N   1 
ATOM   1245  C CA  . HIS A 1 234 ? 138.510 83.227  88.616  1.00 118.76 ? 234 HIS A CA  1 
ATOM   1246  C C   . HIS A 1 234 ? 138.332 82.725  90.050  1.00 121.25 ? 234 HIS A C   1 
ATOM   1247  O O   . HIS A 1 234 ? 138.354 81.523  90.300  1.00 120.06 ? 234 HIS A O   1 
ATOM   1248  C CB  . HIS A 1 234 ? 139.850 83.960  88.450  1.00 117.31 ? 234 HIS A CB  1 
ATOM   1249  C CG  . HIS A 1 234 ? 140.042 84.540  87.074  1.00 116.42 ? 234 HIS A CG  1 
ATOM   1250  N ND1 . HIS A 1 234 ? 140.234 83.803  85.905  1.00 117.99 ? 234 HIS A ND1 1 
ATOM   1251  C CD2 . HIS A 1 234 ? 139.994 85.865  86.760  1.00 116.94 ? 234 HIS A CD2 1 
ATOM   1252  C CE1 . HIS A 1 234 ? 140.296 84.705  84.914  1.00 120.01 ? 234 HIS A CE1 1 
ATOM   1253  N NE2 . HIS A 1 234 ? 140.150 85.948  85.396  1.00 119.63 ? 234 HIS A NE2 1 
ATOM   1254  N N   . GLN A 1 235 ? 138.035 83.682  90.938  1.00 119.94 ? 235 GLN A N   1 
ATOM   1255  C CA  . GLN A 1 235 ? 137.765 83.373  92.362  1.00 116.37 ? 235 GLN A CA  1 
ATOM   1256  C C   . GLN A 1 235 ? 136.994 84.570  92.929  1.00 119.53 ? 235 GLN A C   1 
ATOM   1257  O O   . GLN A 1 235 ? 137.651 85.568  93.264  1.00 117.29 ? 235 GLN A O   1 
ATOM   1258  C CB  . GLN A 1 235 ? 139.069 83.155  93.124  1.00 115.66 ? 235 GLN A CB  1 
ATOM   1259  C CG  . GLN A 1 235 ? 138.886 83.131  94.634  1.00 120.55 ? 235 GLN A CG  1 
ATOM   1260  C CD  . GLN A 1 235 ? 140.082 82.564  95.357  1.00 120.68 ? 235 GLN A CD  1 
ATOM   1261  O OE1 . GLN A 1 235 ? 141.127 82.310  94.764  1.00 116.82 ? 235 GLN A OE1 1 
ATOM   1262  N NE2 . GLN A 1 235 ? 139.932 82.360  96.655  1.00 118.62 ? 235 GLN A NE2 1 
ATOM   1263  N N   . PRO A 1 236 ? 135.640 84.554  92.984  1.00 117.84 ? 236 PRO A N   1 
ATOM   1264  C CA  . PRO A 1 236 ? 134.862 85.634  93.571  1.00 115.34 ? 236 PRO A CA  1 
ATOM   1265  C C   . PRO A 1 236 ? 135.031 85.650  95.096  1.00 111.69 ? 236 PRO A C   1 
ATOM   1266  O O   . PRO A 1 236 ? 134.970 84.611  95.754  1.00 109.82 ? 236 PRO A O   1 
ATOM   1267  C CB  . PRO A 1 236 ? 133.423 85.373  93.130  1.00 110.66 ? 236 PRO A CB  1 
ATOM   1268  C CG  . PRO A 1 236 ? 133.366 83.864  92.932  1.00 109.75 ? 236 PRO A CG  1 
ATOM   1269  C CD  . PRO A 1 236 ? 134.774 83.506  92.473  1.00 111.32 ? 236 PRO A CD  1 
ATOM   1270  N N   . ALA A 1 237 ? 135.240 86.834  95.662  1.00 104.22 ? 237 ALA A N   1 
ATOM   1271  C CA  . ALA A 1 237 ? 135.266 87.059  97.093  1.00 102.71 ? 237 ALA A CA  1 
ATOM   1272  C C   . ALA A 1 237 ? 133.889 86.764  97.694  1.00 107.33 ? 237 ALA A C   1 
ATOM   1273  O O   . ALA A 1 237 ? 132.881 87.327  97.271  1.00 108.63 ? 237 ALA A O   1 
ATOM   1274  C CB  . ALA A 1 237 ? 135.687 88.503  97.360  1.00 99.93  ? 237 ALA A CB  1 
ATOM   1275  N N   . SER A 1 238 ? 133.811 85.892  98.692  1.00 97.91  ? 238 SER A N   1 
ATOM   1276  C CA  . SER A 1 238 ? 132.560 85.655  99.401  1.00 94.82  ? 238 SER A CA  1 
ATOM   1277  C C   . SER A 1 238 ? 132.266 86.816  100.349 1.00 96.55  ? 238 SER A C   1 
ATOM   1278  O O   . SER A 1 238 ? 133.063 87.111  101.235 1.00 96.76  ? 238 SER A O   1 
ATOM   1279  C CB  . SER A 1 238 ? 132.630 84.325  100.142 1.00 95.03  ? 238 SER A CB  1 
ATOM   1280  O OG  . SER A 1 238 ? 131.407 84.080  100.797 1.00 99.13  ? 238 SER A OG  1 
ATOM   1281  N N   . LEU A 1 239 ? 131.101 87.451  100.215 1.00 93.87  ? 239 LEU A N   1 
ATOM   1282  C CA  . LEU A 1 239 ? 130.613 88.426  101.197 1.00 91.60  ? 239 LEU A CA  1 
ATOM   1283  C C   . LEU A 1 239 ? 130.344 87.790  102.563 1.00 90.88  ? 239 LEU A C   1 
ATOM   1284  O O   . LEU A 1 239 ? 130.260 88.505  103.549 1.00 90.25  ? 239 LEU A O   1 
ATOM   1285  C CB  . LEU A 1 239 ? 129.341 89.107  100.667 1.00 92.24  ? 239 LEU A CB  1 
ATOM   1286  C CG  . LEU A 1 239 ? 129.652 90.168  99.608  1.00 91.60  ? 239 LEU A CG  1 
ATOM   1287  C CD1 . LEU A 1 239 ? 128.437 90.452  98.744  1.00 94.30  ? 239 LEU A CD1 1 
ATOM   1288  C CD2 . LEU A 1 239 ? 130.080 91.482  100.251 1.00 87.45  ? 239 LEU A CD2 1 
ATOM   1289  N N   . GLU A 1 240 ? 130.227 86.466  102.649 1.00 99.05  ? 240 GLU A N   1 
ATOM   1290  C CA  . GLU A 1 240 ? 130.081 85.735  103.908 1.00 101.82 ? 240 GLU A CA  1 
ATOM   1291  C C   . GLU A 1 240 ? 131.418 85.466  104.622 1.00 104.53 ? 240 GLU A C   1 
ATOM   1292  O O   . GLU A 1 240 ? 131.413 84.947  105.737 1.00 105.99 ? 240 GLU A O   1 
ATOM   1293  C CB  . GLU A 1 240 ? 129.386 84.389  103.656 1.00 101.81 ? 240 GLU A CB  1 
ATOM   1294  C CG  . GLU A 1 240 ? 128.092 84.473  102.848 1.00 103.97 ? 240 GLU A CG  1 
ATOM   1295  C CD  . GLU A 1 240 ? 127.455 83.083  102.709 1.00 106.97 ? 240 GLU A CD  1 
ATOM   1296  O OE1 . GLU A 1 240 ? 127.173 82.436  103.741 1.00 103.77 ? 240 GLU A OE1 1 
ATOM   1297  O OE2 . GLU A 1 240 ? 127.252 82.623  101.565 1.00 105.08 ? 240 GLU A OE2 1 
ATOM   1298  N N   . ALA A 1 241 ? 132.568 85.746  104.000 1.00 92.00  ? 241 ALA A N   1 
ATOM   1299  C CA  . ALA A 1 241 ? 133.885 85.439  104.560 1.00 88.39  ? 241 ALA A CA  1 
ATOM   1300  C C   . ALA A 1 241 ? 134.229 86.308  105.776 1.00 88.54  ? 241 ALA A C   1 
ATOM   1301  O O   . ALA A 1 241 ? 133.895 87.491  105.829 1.00 91.13  ? 241 ALA A O   1 
ATOM   1302  C CB  . ALA A 1 241 ? 134.945 85.577  103.471 1.00 87.38  ? 241 ALA A CB  1 
ATOM   1303  N N   . THR A 1 242 ? 134.937 85.726  106.744 1.00 82.95  ? 242 THR A N   1 
ATOM   1304  C CA  . THR A 1 242 ? 135.210 86.334  108.052 1.00 85.09  ? 242 THR A CA  1 
ATOM   1305  C C   . THR A 1 242 ? 136.688 86.333  108.424 1.00 91.34  ? 242 THR A C   1 
ATOM   1306  O O   . THR A 1 242 ? 137.410 85.381  108.141 1.00 89.94  ? 242 THR A O   1 
ATOM   1307  C CB  . THR A 1 242 ? 134.436 85.616  109.162 1.00 85.26  ? 242 THR A CB  1 
ATOM   1308  O OG1 . THR A 1 242 ? 134.775 84.249  109.221 1.00 90.68  ? 242 THR A OG1 1 
ATOM   1309  C CG2 . THR A 1 242 ? 132.925 85.705  109.011 1.00 86.22  ? 242 THR A CG2 1 
ATOM   1310  N N   . ASP A 1 243 ? 137.132 87.371  109.128 1.00 81.71  ? 243 ASP A N   1 
ATOM   1311  C CA  . ASP A 1 243 ? 138.461 87.427  109.737 1.00 73.84  ? 243 ASP A CA  1 
ATOM   1312  C C   . ASP A 1 243 ? 138.601 86.568  111.022 1.00 79.08  ? 243 ASP A C   1 
ATOM   1313  O O   . ASP A 1 243 ? 137.690 85.826  111.391 1.00 80.19  ? 243 ASP A O   1 
ATOM   1314  C CB  . ASP A 1 243 ? 138.832 88.900  109.937 1.00 78.49  ? 243 ASP A CB  1 
ATOM   1315  C CG  . ASP A 1 243 ? 138.276 89.627  111.159 1.00 82.11  ? 243 ASP A CG  1 
ATOM   1316  O OD1 . ASP A 1 243 ? 137.575 88.995  111.971 1.00 88.38  ? 243 ASP A OD1 1 
ATOM   1317  O OD2 . ASP A 1 243 ? 138.571 90.834  111.293 1.00 88.00  ? 243 ASP A OD2 1 
ATOM   1318  N N   . SER A 1 244 ? 139.738 86.649  111.723 1.00 90.34  ? 244 SER A N   1 
ATOM   1319  C CA  . SER A 1 244 ? 139.997 85.910  112.973 1.00 90.42  ? 244 SER A CA  1 
ATOM   1320  C C   . SER A 1 244 ? 139.082 86.268  114.148 1.00 87.38  ? 244 SER A C   1 
ATOM   1321  O O   . SER A 1 244 ? 138.949 85.461  115.067 1.00 85.83  ? 244 SER A O   1 
ATOM   1322  C CB  . SER A 1 244 ? 141.442 86.127  113.433 1.00 88.89  ? 244 SER A CB  1 
ATOM   1323  O OG  . SER A 1 244 ? 141.661 87.442  113.889 1.00 90.21  ? 244 SER A OG  1 
ATOM   1324  N N   . LEU A 1 245 ? 138.440 87.437  114.145 1.00 79.85  ? 245 LEU A N   1 
ATOM   1325  C CA  . LEU A 1 245 ? 137.423 87.846  115.121 1.00 80.26  ? 245 LEU A CA  1 
ATOM   1326  C C   . LEU A 1 245 ? 136.010 87.436  114.682 1.00 83.37  ? 245 LEU A C   1 
ATOM   1327  O O   . LEU A 1 245 ? 135.037 87.714  115.380 1.00 85.23  ? 245 LEU A O   1 
ATOM   1328  C CB  . LEU A 1 245 ? 137.476 89.369  115.342 1.00 83.81  ? 245 LEU A CB  1 
ATOM   1329  C CG  . LEU A 1 245 ? 138.842 89.948  115.727 1.00 86.52  ? 245 LEU A CG  1 
ATOM   1330  C CD1 . LEU A 1 245 ? 138.713 91.459  115.903 1.00 82.97  ? 245 LEU A CD1 1 
ATOM   1331  C CD2 . LEU A 1 245 ? 139.367 89.348  117.029 1.00 84.76  ? 245 LEU A CD2 1 
ATOM   1332  N N   . GLY A 1 246 ? 135.871 86.818  113.510 1.00 81.20  ? 246 GLY A N   1 
ATOM   1333  C CA  . GLY A 1 246 ? 134.595 86.513  112.881 1.00 71.44  ? 246 GLY A CA  1 
ATOM   1334  C C   . GLY A 1 246 ? 133.968 87.706  112.159 1.00 73.50  ? 246 GLY A C   1 
ATOM   1335  O O   . GLY A 1 246 ? 132.837 87.602  111.701 1.00 83.55  ? 246 GLY A O   1 
ATOM   1336  N N   . ASN A 1 247 ? 134.653 88.845  112.046 1.00 71.61  ? 247 ASN A N   1 
ATOM   1337  C CA  . ASN A 1 247 ? 134.120 90.030  111.390 1.00 67.02  ? 247 ASN A CA  1 
ATOM   1338  C C   . ASN A 1 247 ? 134.026 89.814  109.876 1.00 73.09  ? 247 ASN A C   1 
ATOM   1339  O O   . ASN A 1 247 ? 135.005 89.477  109.219 1.00 74.88  ? 247 ASN A O   1 
ATOM   1340  C CB  . ASN A 1 247 ? 134.976 91.257  111.744 1.00 63.32  ? 247 ASN A CB  1 
ATOM   1341  C CG  . ASN A 1 247 ? 134.710 91.814  113.125 1.00 69.90  ? 247 ASN A CG  1 
ATOM   1342  O OD1 . ASN A 1 247 ? 133.773 91.455  113.806 1.00 78.84  ? 247 ASN A OD1 1 
ATOM   1343  N ND2 . ASN A 1 247 ? 135.497 92.748  113.579 1.00 75.50  ? 247 ASN A ND2 1 
ATOM   1344  N N   . THR A 1 248 ? 132.841 90.045  109.321 1.00 81.91  ? 248 THR A N   1 
ATOM   1345  C CA  . THR A 1 248 ? 132.577 90.176  107.881 1.00 78.55  ? 248 THR A CA  1 
ATOM   1346  C C   . THR A 1 248 ? 132.986 91.580  107.412 1.00 74.39  ? 248 THR A C   1 
ATOM   1347  O O   . THR A 1 248 ? 133.245 92.450  108.241 1.00 75.25  ? 248 THR A O   1 
ATOM   1348  C CB  . THR A 1 248 ? 131.080 89.884  107.642 1.00 80.79  ? 248 THR A CB  1 
ATOM   1349  O OG1 . THR A 1 248 ? 130.777 88.595  108.110 1.00 75.16  ? 248 THR A OG1 1 
ATOM   1350  C CG2 . THR A 1 248 ? 130.635 89.906  106.194 1.00 82.91  ? 248 THR A CG2 1 
ATOM   1351  N N   . VAL A 1 249 ? 133.018 91.877  106.114 1.00 62.90  ? 249 VAL A N   1 
ATOM   1352  C CA  . VAL A 1 249 ? 133.351 93.226  105.604 1.00 65.71  ? 249 VAL A CA  1 
ATOM   1353  C C   . VAL A 1 249 ? 132.470 94.343  106.187 1.00 72.87  ? 249 VAL A C   1 
ATOM   1354  O O   . VAL A 1 249 ? 132.936 95.461  106.370 1.00 81.07  ? 249 VAL A O   1 
ATOM   1355  C CB  . VAL A 1 249 ? 133.375 93.249  104.063 1.00 64.51  ? 249 VAL A CB  1 
ATOM   1356  C CG1 . VAL A 1 249 ? 132.044 92.905  103.404 1.00 71.51  ? 249 VAL A CG1 1 
ATOM   1357  C CG2 . VAL A 1 249 ? 133.812 94.612  103.538 1.00 67.79  ? 249 VAL A CG2 1 
ATOM   1358  N N   . LEU A 1 250 ? 131.225 94.039  106.566 1.00 71.29  ? 250 LEU A N   1 
ATOM   1359  C CA  . LEU A 1 250 ? 130.299 94.986  107.187 1.00 63.40  ? 250 LEU A CA  1 
ATOM   1360  C C   . LEU A 1 250 ? 130.640 95.266  108.659 1.00 66.69  ? 250 LEU A C   1 
ATOM   1361  O O   . LEU A 1 250 ? 130.523 96.403  109.099 1.00 70.71  ? 250 LEU A O   1 
ATOM   1362  C CB  . LEU A 1 250 ? 128.855 94.485  107.011 1.00 70.30  ? 250 LEU A CB  1 
ATOM   1363  C CG  . LEU A 1 250 ? 128.365 94.315  105.561 1.00 64.05  ? 250 LEU A CG  1 
ATOM   1364  C CD1 . LEU A 1 250 ? 126.909 93.877  105.568 1.00 68.54  ? 250 LEU A CD1 1 
ATOM   1365  C CD2 . LEU A 1 250 ? 128.463 95.599  104.746 1.00 65.55  ? 250 LEU A CD2 1 
ATOM   1366  N N   . HIS A 1 251 ? 131.140 94.279  109.394 1.00 65.41  ? 251 HIS A N   1 
ATOM   1367  C CA  . HIS A 1 251 ? 131.735 94.519  110.697 1.00 62.50  ? 251 HIS A CA  1 
ATOM   1368  C C   . HIS A 1 251 ? 133.041 95.300  110.578 1.00 71.34  ? 251 HIS A C   1 
ATOM   1369  O O   . HIS A 1 251 ? 133.294 96.181  111.388 1.00 80.41  ? 251 HIS A O   1 
ATOM   1370  C CB  . HIS A 1 251 ? 132.012 93.196  111.394 1.00 71.17  ? 251 HIS A CB  1 
ATOM   1371  C CG  . HIS A 1 251 ? 130.853 92.260  111.549 1.00 67.08  ? 251 HIS A CG  1 
ATOM   1372  N ND1 . HIS A 1 251 ? 130.460 91.313  110.611 1.00 61.43  ? 251 HIS A ND1 1 
ATOM   1373  C CD2 . HIS A 1 251 ? 130.124 92.089  112.679 1.00 63.84  ? 251 HIS A CD2 1 
ATOM   1374  C CE1 . HIS A 1 251 ? 129.500 90.590  111.191 1.00 63.24  ? 251 HIS A CE1 1 
ATOM   1375  N NE2 . HIS A 1 251 ? 129.288 91.033  112.433 1.00 68.48  ? 251 HIS A NE2 1 
ATOM   1376  N N   . ALA A 1 252 ? 133.861 95.018  109.565 1.00 63.39  ? 252 ALA A N   1 
ATOM   1377  C CA  . ALA A 1 252 ? 135.098 95.750  109.321 1.00 56.92  ? 252 ALA A CA  1 
ATOM   1378  C C   . ALA A 1 252 ? 134.835 97.231  109.037 1.00 61.20  ? 252 ALA A C   1 
ATOM   1379  O O   . ALA A 1 252 ? 135.430 98.083  109.686 1.00 74.16  ? 252 ALA A O   1 
ATOM   1380  C CB  . ALA A 1 252 ? 135.879 95.074  108.196 1.00 57.80  ? 252 ALA A CB  1 
ATOM   1381  N N   . LEU A 1 253 ? 133.881 97.568  108.171 1.00 66.34  ? 253 LEU A N   1 
ATOM   1382  C CA  . LEU A 1 253 ? 133.466 98.953  107.929 1.00 59.45  ? 253 LEU A CA  1 
ATOM   1383  C C   . LEU A 1 253 ? 132.907 99.643  109.175 1.00 54.46  ? 253 LEU A C   1 
ATOM   1384  O O   . LEU A 1 253 ? 133.206 100.805 109.413 1.00 63.43  ? 253 LEU A O   1 
ATOM   1385  C CB  . LEU A 1 253 ? 132.430 98.977  106.804 1.00 60.41  ? 253 LEU A CB  1 
ATOM   1386  C CG  . LEU A 1 253 ? 133.048 98.811  105.416 1.00 60.40  ? 253 LEU A CG  1 
ATOM   1387  C CD1 . LEU A 1 253 ? 131.932 98.602  104.413 1.00 65.56  ? 253 LEU A CD1 1 
ATOM   1388  C CD2 . LEU A 1 253 ? 133.822 100.049 104.970 1.00 63.82  ? 253 LEU A CD2 1 
ATOM   1389  N N   . VAL A 1 254 ? 132.161 98.942  110.027 1.00 63.22  ? 254 VAL A N   1 
ATOM   1390  C CA  . VAL A 1 254 ? 131.718 99.488  111.320 1.00 62.49  ? 254 VAL A CA  1 
ATOM   1391  C C   . VAL A 1 254 ? 132.896 99.726  112.267 1.00 63.46  ? 254 VAL A C   1 
ATOM   1392  O O   . VAL A 1 254 ? 132.944 100.751 112.945 1.00 73.90  ? 254 VAL A O   1 
ATOM   1393  C CB  . VAL A 1 254 ? 130.654 98.570  111.933 1.00 67.15  ? 254 VAL A CB  1 
ATOM   1394  C CG1 . VAL A 1 254 ? 130.366 98.909  113.387 1.00 73.00  ? 254 VAL A CG1 1 
ATOM   1395  C CG2 . VAL A 1 254 ? 129.337 98.700  111.168 1.00 64.15  ? 254 VAL A CG2 1 
ATOM   1396  N N   . MET A 1 255 ? 133.896 98.846  112.301 1.00 67.69  ? 255 MET A N   1 
ATOM   1397  C CA  . MET A 1 255 ? 135.105 99.042  113.112 1.00 65.98  ? 255 MET A CA  1 
ATOM   1398  C C   . MET A 1 255 ? 135.907 100.275 112.684 1.00 69.56  ? 255 MET A C   1 
ATOM   1399  O O   . MET A 1 255 ? 136.483 100.956 113.526 1.00 73.49  ? 255 MET A O   1 
ATOM   1400  C CB  . MET A 1 255 ? 136.002 97.803  113.037 1.00 65.07  ? 255 MET A CB  1 
ATOM   1401  C CG  . MET A 1 255 ? 135.497 96.661  113.906 1.00 61.67  ? 255 MET A CG  1 
ATOM   1402  S SD  . MET A 1 255 ? 135.618 97.012  115.677 1.00 79.34  ? 255 MET A SD  1 
ATOM   1403  C CE  . MET A 1 255 ? 135.695 95.320  116.308 1.00 69.47  ? 255 MET A CE  1 
ATOM   1404  N N   . ILE A 1 256 ? 135.895 100.594 111.395 1.00 77.73  ? 256 ILE A N   1 
ATOM   1405  C CA  . ILE A 1 256 ? 136.699 101.643 110.747 1.00 72.38  ? 256 ILE A CA  1 
ATOM   1406  C C   . ILE A 1 256 ? 135.977 102.985 110.614 1.00 75.84  ? 256 ILE A C   1 
ATOM   1407  O O   . ILE A 1 256 ? 136.615 104.008 110.371 1.00 80.29  ? 256 ILE A O   1 
ATOM   1408  C CB  . ILE A 1 256 ? 137.185 101.040 109.421 1.00 72.64  ? 256 ILE A CB  1 
ATOM   1409  C CG1 . ILE A 1 256 ? 138.335 100.101 109.825 1.00 75.38  ? 256 ILE A CG1 1 
ATOM   1410  C CG2 . ILE A 1 256 ? 137.614 102.018 108.333 1.00 69.78  ? 256 ILE A CG2 1 
ATOM   1411  C CD1 . ILE A 1 256 ? 138.537 98.960  108.859 1.00 75.53  ? 256 ILE A CD1 1 
ATOM   1412  N N   . ALA A 1 257 ? 134.668 103.020 110.848 1.00 77.53  ? 257 ALA A N   1 
ATOM   1413  C CA  . ALA A 1 257 ? 133.921 104.262 110.935 1.00 74.31  ? 257 ALA A CA  1 
ATOM   1414  C C   . ALA A 1 257 ? 134.466 105.166 112.051 1.00 78.91  ? 257 ALA A C   1 
ATOM   1415  O O   . ALA A 1 257 ? 134.614 104.731 113.189 1.00 82.87  ? 257 ALA A O   1 
ATOM   1416  C CB  . ALA A 1 257 ? 132.447 103.935 111.156 1.00 75.42  ? 257 ALA A CB  1 
ATOM   1417  N N   . ASP A 1 258 ? 134.678 106.438 111.750 1.00 97.99  ? 258 ASP A N   1 
ATOM   1418  C CA  . ASP A 1 258 ? 134.886 107.529 112.699 1.00 99.80  ? 258 ASP A CA  1 
ATOM   1419  C C   . ASP A 1 258 ? 133.723 108.510 112.542 1.00 105.01 ? 258 ASP A C   1 
ATOM   1420  O O   . ASP A 1 258 ? 133.152 108.653 111.461 1.00 105.93 ? 258 ASP A O   1 
ATOM   1421  C CB  . ASP A 1 258 ? 136.221 108.251 112.458 1.00 101.45 ? 258 ASP A CB  1 
ATOM   1422  C CG  . ASP A 1 258 ? 137.457 107.491 112.951 1.00 107.18 ? 258 ASP A CG  1 
ATOM   1423  O OD1 . ASP A 1 258 ? 137.335 106.636 113.851 1.00 108.56 ? 258 ASP A OD1 1 
ATOM   1424  O OD2 . ASP A 1 258 ? 138.572 107.822 112.496 1.00 104.13 ? 258 ASP A OD2 1 
ATOM   1425  N N   . ASN A 1 259 ? 133.340 109.189 113.614 1.00 101.43 ? 259 ASN A N   1 
ATOM   1426  C CA  . ASN A 1 259 ? 132.122 109.999 113.627 1.00 103.46 ? 259 ASN A CA  1 
ATOM   1427  C C   . ASN A 1 259 ? 132.278 111.370 112.929 1.00 104.57 ? 259 ASN A C   1 
ATOM   1428  O O   . ASN A 1 259 ? 131.427 112.244 113.075 1.00 104.00 ? 259 ASN A O   1 
ATOM   1429  C CB  . ASN A 1 259 ? 131.599 110.075 115.069 1.00 101.81 ? 259 ASN A CB  1 
ATOM   1430  C CG  . ASN A 1 259 ? 131.424 108.697 115.683 1.00 98.20  ? 259 ASN A CG  1 
ATOM   1431  O OD1 . ASN A 1 259 ? 130.657 107.874 115.214 1.00 94.50  ? 259 ASN A OD1 1 
ATOM   1432  N ND2 . ASN A 1 259 ? 132.152 108.388 116.731 1.00 99.37  ? 259 ASN A ND2 1 
ATOM   1433  N N   . SER A 1 260 ? 133.360 111.584 112.173 1.00 106.87 ? 260 SER A N   1 
ATOM   1434  C CA  . SER A 1 260 ? 133.570 112.773 111.343 1.00 106.29 ? 260 SER A CA  1 
ATOM   1435  C C   . SER A 1 260 ? 132.731 112.706 110.059 1.00 105.46 ? 260 SER A C   1 
ATOM   1436  O O   . SER A 1 260 ? 132.434 111.615 109.569 1.00 106.21 ? 260 SER A O   1 
ATOM   1437  C CB  . SER A 1 260 ? 135.061 112.928 111.025 1.00 106.59 ? 260 SER A CB  1 
ATOM   1438  O OG  . SER A 1 260 ? 135.533 111.846 110.249 1.00 105.89 ? 260 SER A OG  1 
ATOM   1439  N N   . PRO A 1 261 ? 132.328 113.844 109.467 1.00 109.40 ? 261 PRO A N   1 
ATOM   1440  C CA  . PRO A 1 261 ? 131.419 113.840 108.320 1.00 111.20 ? 261 PRO A CA  1 
ATOM   1441  C C   . PRO A 1 261 ? 132.058 113.269 107.048 1.00 108.89 ? 261 PRO A C   1 
ATOM   1442  O O   . PRO A 1 261 ? 131.363 112.681 106.228 1.00 102.36 ? 261 PRO A O   1 
ATOM   1443  C CB  . PRO A 1 261 ? 130.987 115.296 108.144 1.00 109.67 ? 261 PRO A CB  1 
ATOM   1444  C CG  . PRO A 1 261 ? 132.127 116.098 108.763 1.00 106.65 ? 261 PRO A CG  1 
ATOM   1445  C CD  . PRO A 1 261 ? 132.594 115.202 109.904 1.00 107.01 ? 261 PRO A CD  1 
ATOM   1446  N N   . GLU A 1 262 ? 133.374 113.396 106.885 1.00 106.55 ? 262 GLU A N   1 
ATOM   1447  C CA  . GLU A 1 262 ? 134.098 112.888 105.713 1.00 108.72 ? 262 GLU A CA  1 
ATOM   1448  C C   . GLU A 1 262 ? 134.272 111.366 105.747 1.00 111.14 ? 262 GLU A C   1 
ATOM   1449  O O   . GLU A 1 262 ? 133.994 110.694 104.756 1.00 110.11 ? 262 GLU A O   1 
ATOM   1450  C CB  . GLU A 1 262 ? 135.465 113.583 105.602 1.00 104.30 ? 262 GLU A CB  1 
ATOM   1451  N N   . ASN A 1 263 ? 134.681 110.794 106.882 1.00 98.28  ? 263 ASN A N   1 
ATOM   1452  C CA  . ASN A 1 263 ? 134.785 109.342 107.032 1.00 94.80  ? 263 ASN A CA  1 
ATOM   1453  C C   . ASN A 1 263 ? 133.398 108.699 106.984 1.00 100.69 ? 263 ASN A C   1 
ATOM   1454  O O   . ASN A 1 263 ? 133.148 107.837 106.145 1.00 101.17 ? 263 ASN A O   1 
ATOM   1455  C CB  . ASN A 1 263 ? 135.539 109.016 108.330 1.00 97.16  ? 263 ASN A CB  1 
ATOM   1456  C CG  . ASN A 1 263 ? 135.582 107.531 108.641 1.00 97.70  ? 263 ASN A CG  1 
ATOM   1457  O OD1 . ASN A 1 263 ? 134.575 106.928 108.956 1.00 100.84 ? 263 ASN A OD1 1 
ATOM   1458  N ND2 . ASN A 1 263 ? 136.720 106.898 108.604 1.00 95.96  ? 263 ASN A ND2 1 
ATOM   1459  N N   . SER A 1 264 ? 132.476 109.132 107.848 1.00 97.85  ? 264 SER A N   1 
ATOM   1460  C CA  . SER A 1 264 ? 131.186 108.458 107.997 1.00 90.45  ? 264 SER A CA  1 
ATOM   1461  C C   . SER A 1 264 ? 130.364 108.474 106.716 1.00 90.04  ? 264 SER A C   1 
ATOM   1462  O O   . SER A 1 264 ? 129.840 107.428 106.351 1.00 95.19  ? 264 SER A O   1 
ATOM   1463  C CB  . SER A 1 264 ? 130.383 109.038 109.156 1.00 92.08  ? 264 SER A CB  1 
ATOM   1464  O OG  . SER A 1 264 ? 130.133 110.411 108.971 1.00 96.92  ? 264 SER A OG  1 
ATOM   1465  N N   . ALA A 1 265 ? 130.302 109.576 105.964 1.00 96.79  ? 265 ALA A N   1 
ATOM   1466  C CA  . ALA A 1 265 ? 129.572 109.607 104.696 1.00 96.00  ? 265 ALA A CA  1 
ATOM   1467  C C   . ALA A 1 265 ? 130.130 108.610 103.675 1.00 95.18  ? 265 ALA A C   1 
ATOM   1468  O O   . ALA A 1 265 ? 129.366 107.931 102.994 1.00 91.71  ? 265 ALA A O   1 
ATOM   1469  C CB  . ALA A 1 265 ? 129.602 111.026 104.139 1.00 95.92  ? 265 ALA A CB  1 
ATOM   1470  N N   . LEU A 1 266 ? 131.453 108.462 103.587 1.00 94.03  ? 266 LEU A N   1 
ATOM   1471  C CA  . LEU A 1 266 ? 132.086 107.526 102.660 1.00 95.89  ? 266 LEU A CA  1 
ATOM   1472  C C   . LEU A 1 266 ? 131.989 106.065 103.125 1.00 94.82  ? 266 LEU A C   1 
ATOM   1473  O O   . LEU A 1 266 ? 131.788 105.185 102.300 1.00 92.68  ? 266 LEU A O   1 
ATOM   1474  C CB  . LEU A 1 266 ? 133.538 107.957 102.418 1.00 95.50  ? 266 LEU A CB  1 
ATOM   1475  C CG  . LEU A 1 266 ? 133.691 109.311 101.698 1.00 99.04  ? 266 LEU A CG  1 
ATOM   1476  C CD1 . LEU A 1 266 ? 135.166 109.687 101.616 1.00 95.37  ? 266 LEU A CD1 1 
ATOM   1477  C CD2 . LEU A 1 266 ? 133.145 109.276 100.273 1.00 95.33  ? 266 LEU A CD2 1 
ATOM   1478  N N   . VAL A 1 267 ? 132.048 105.791 104.433 1.00 88.41  ? 267 VAL A N   1 
ATOM   1479  C CA  . VAL A 1 267 ? 131.768 104.454 104.994 1.00 86.31  ? 267 VAL A CA  1 
ATOM   1480  C C   . VAL A 1 267 ? 130.313 104.052 104.770 1.00 83.60  ? 267 VAL A C   1 
ATOM   1481  O O   . VAL A 1 267 ? 130.058 102.910 104.419 1.00 85.44  ? 267 VAL A O   1 
ATOM   1482  C CB  . VAL A 1 267 ? 132.130 104.380 106.485 1.00 79.39  ? 267 VAL A CB  1 
ATOM   1483  C CG1 . VAL A 1 267 ? 131.645 103.091 107.148 1.00 81.05  ? 267 VAL A CG1 1 
ATOM   1484  C CG2 . VAL A 1 267 ? 133.648 104.424 106.652 1.00 84.91  ? 267 VAL A CG2 1 
ATOM   1485  N N   . ILE A 1 268 ? 129.362 104.972 104.912 1.00 78.98  ? 268 ILE A N   1 
ATOM   1486  C CA  . ILE A 1 268 ? 127.941 104.742 104.641 1.00 73.75  ? 268 ILE A CA  1 
ATOM   1487  C C   . ILE A 1 268 ? 127.708 104.361 103.174 1.00 81.37  ? 268 ILE A C   1 
ATOM   1488  O O   . ILE A 1 268 ? 126.997 103.403 102.897 1.00 84.20  ? 268 ILE A O   1 
ATOM   1489  C CB  . ILE A 1 268 ? 127.148 105.989 105.080 1.00 79.17  ? 268 ILE A CB  1 
ATOM   1490  C CG1 . ILE A 1 268 ? 126.970 105.947 106.611 1.00 74.90  ? 268 ILE A CG1 1 
ATOM   1491  C CG2 . ILE A 1 268 ? 125.799 106.118 104.369 1.00 81.25  ? 268 ILE A CG2 1 
ATOM   1492  C CD1 . ILE A 1 268 ? 126.538 107.284 107.215 1.00 76.43  ? 268 ILE A CD1 1 
ATOM   1493  N N   . HIS A 1 269 ? 128.354 105.039 102.223 1.00 94.96  ? 269 HIS A N   1 
ATOM   1494  C CA  . HIS A 1 269 ? 128.278 104.654 100.812 1.00 92.26  ? 269 HIS A CA  1 
ATOM   1495  C C   . HIS A 1 269 ? 128.912 103.289 100.544 1.00 89.43  ? 269 HIS A C   1 
ATOM   1496  O O   . HIS A 1 269 ? 128.325 102.466 99.849  1.00 89.89  ? 269 HIS A O   1 
ATOM   1497  C CB  . HIS A 1 269 ? 128.920 105.726 99.926  1.00 88.74  ? 269 HIS A CB  1 
ATOM   1498  C CG  . HIS A 1 269 ? 128.045 106.937 99.754  1.00 95.88  ? 269 HIS A CG  1 
ATOM   1499  N ND1 . HIS A 1 269 ? 127.827 107.931 100.676 1.00 98.33  ? 269 HIS A ND1 1 
ATOM   1500  C CD2 . HIS A 1 269 ? 127.203 107.181 98.710  1.00 96.27  ? 269 HIS A CD2 1 
ATOM   1501  C CE1 . HIS A 1 269 ? 126.892 108.764 100.196 1.00 97.81  ? 269 HIS A CE1 1 
ATOM   1502  N NE2 . HIS A 1 269 ? 126.478 108.344 98.992  1.00 97.81  ? 269 HIS A NE2 1 
ATOM   1503  N N   . MET A 1 270 ? 130.090 103.025 101.109 1.00 85.31  ? 270 MET A N   1 
ATOM   1504  C CA  . MET A 1 270 ? 130.774 101.742 100.963 1.00 82.46  ? 270 MET A CA  1 
ATOM   1505  C C   . MET A 1 270 ? 129.963 100.584 101.552 1.00 82.81  ? 270 MET A C   1 
ATOM   1506  O O   . MET A 1 270 ? 129.835 99.537  100.926 1.00 82.60  ? 270 MET A O   1 
ATOM   1507  C CB  . MET A 1 270 ? 132.161 101.857 101.595 1.00 79.32  ? 270 MET A CB  1 
ATOM   1508  C CG  . MET A 1 270 ? 133.087 100.718 101.188 1.00 83.59  ? 270 MET A CG  1 
ATOM   1509  S SD  . MET A 1 270 ? 133.690 100.802 99.484  1.00 81.19  ? 270 MET A SD  1 
ATOM   1510  C CE  . MET A 1 270 ? 132.902 99.320  98.841  1.00 88.79  ? 270 MET A CE  1 
ATOM   1511  N N   . TYR A 1 271 ? 129.346 100.786 102.714 1.00 81.71  ? 271 TYR A N   1 
ATOM   1512  C CA  . TYR A 1 271 ? 128.470 99.820  103.368 1.00 77.50  ? 271 TYR A CA  1 
ATOM   1513  C C   . TYR A 1 271 ? 127.218 99.528  102.531 1.00 78.91  ? 271 TYR A C   1 
ATOM   1514  O O   . TYR A 1 271 ? 126.918 98.373  102.251 1.00 78.22  ? 271 TYR A O   1 
ATOM   1515  C CB  . TYR A 1 271 ? 128.116 100.378 104.752 1.00 79.14  ? 271 TYR A CB  1 
ATOM   1516  C CG  . TYR A 1 271 ? 127.398 99.417  105.669 1.00 75.78  ? 271 TYR A CG  1 
ATOM   1517  C CD1 . TYR A 1 271 ? 126.052 99.086  105.440 1.00 72.86  ? 271 TYR A CD1 1 
ATOM   1518  C CD2 . TYR A 1 271 ? 128.081 98.857  106.764 1.00 75.64  ? 271 TYR A CD2 1 
ATOM   1519  C CE1 . TYR A 1 271 ? 125.404 98.164  106.273 1.00 75.68  ? 271 TYR A CE1 1 
ATOM   1520  C CE2 . TYR A 1 271 ? 127.424 97.956  107.616 1.00 76.79  ? 271 TYR A CE2 1 
ATOM   1521  C CZ  . TYR A 1 271 ? 126.087 97.601  107.364 1.00 80.94  ? 271 TYR A CZ  1 
ATOM   1522  O OH  . TYR A 1 271 ? 125.454 96.730  108.182 1.00 79.16  ? 271 TYR A OH  1 
ATOM   1523  N N   . ASP A 1 272 ? 126.503 100.562 102.084 1.00 83.27  ? 272 ASP A N   1 
ATOM   1524  C CA  . ASP A 1 272 ? 125.297 100.414 101.270 1.00 80.53  ? 272 ASP A CA  1 
ATOM   1525  C C   . ASP A 1 272 ? 125.555 99.698  99.950  1.00 88.88  ? 272 ASP A C   1 
ATOM   1526  O O   . ASP A 1 272 ? 124.804 98.792  99.603  1.00 91.18  ? 272 ASP A O   1 
ATOM   1527  C CB  . ASP A 1 272 ? 124.681 101.780 100.962 1.00 86.28  ? 272 ASP A CB  1 
ATOM   1528  C CG  . ASP A 1 272 ? 123.894 102.385 102.119 1.00 93.60  ? 272 ASP A CG  1 
ATOM   1529  O OD1 . ASP A 1 272 ? 123.659 101.694 103.132 1.00 94.12  ? 272 ASP A OD1 1 
ATOM   1530  O OD2 . ASP A 1 272 ? 123.430 103.536 101.969 1.00 93.96  ? 272 ASP A OD2 1 
ATOM   1531  N N   . GLY A 1 273 ? 126.601 100.053 99.202  1.00 86.29  ? 273 GLY A N   1 
ATOM   1532  C CA  . GLY A 1 273 ? 126.875 99.366  97.941  1.00 77.94  ? 273 GLY A CA  1 
ATOM   1533  C C   . GLY A 1 273 ? 127.280 97.904  98.128  1.00 81.71  ? 273 GLY A C   1 
ATOM   1534  O O   . GLY A 1 273 ? 126.895 97.070  97.317  1.00 82.01  ? 273 GLY A O   1 
ATOM   1535  N N   . LEU A 1 274 ? 127.989 97.544  99.200  1.00 85.75  ? 274 LEU A N   1 
ATOM   1536  C CA  . LEU A 1 274 ? 128.269 96.142  99.520  1.00 84.59  ? 274 LEU A CA  1 
ATOM   1537  C C   . LEU A 1 274 ? 127.010 95.379  99.918  1.00 85.15  ? 274 LEU A C   1 
ATOM   1538  O O   . LEU A 1 274 ? 126.791 94.272  99.441  1.00 87.11  ? 274 LEU A O   1 
ATOM   1539  C CB  . LEU A 1 274 ? 129.274 96.060  100.672 1.00 84.30  ? 274 LEU A CB  1 
ATOM   1540  C CG  . LEU A 1 274 ? 130.709 96.416  100.287 1.00 79.88  ? 274 LEU A CG  1 
ATOM   1541  C CD1 . LEU A 1 274 ? 131.514 96.502  101.567 1.00 84.99  ? 274 LEU A CD1 1 
ATOM   1542  C CD2 . LEU A 1 274 ? 131.350 95.356  99.402  1.00 78.03  ? 274 LEU A CD2 1 
ATOM   1543  N N   . LEU A 1 275 ? 126.114 95.997  100.681 1.00 85.61  ? 275 LEU A N   1 
ATOM   1544  C CA  . LEU A 1 275 ? 124.820 95.420  101.026 1.00 83.56  ? 275 LEU A CA  1 
ATOM   1545  C C   . LEU A 1 275 ? 123.910 95.236  99.797  1.00 77.98  ? 275 LEU A C   1 
ATOM   1546  O O   . LEU A 1 275 ? 123.348 94.163  99.604  1.00 78.79  ? 275 LEU A O   1 
ATOM   1547  C CB  . LEU A 1 275 ? 124.191 96.327  102.088 1.00 80.71  ? 275 LEU A CB  1 
ATOM   1548  C CG  . LEU A 1 275 ? 122.931 95.747  102.717 1.00 78.82  ? 275 LEU A CG  1 
ATOM   1549  C CD1 . LEU A 1 275 ? 123.239 94.573  103.628 1.00 77.62  ? 275 LEU A CD1 1 
ATOM   1550  C CD2 . LEU A 1 275 ? 122.264 96.834  103.523 1.00 80.66  ? 275 LEU A CD2 1 
ATOM   1551  N N   . GLN A 1 276 ? 123.821 96.239  98.922  1.00 86.32  ? 276 GLN A N   1 
ATOM   1552  C CA  . GLN A 1 276 ? 123.136 96.139  97.632  1.00 85.04  ? 276 GLN A CA  1 
ATOM   1553  C C   . GLN A 1 276 ? 123.772 95.088  96.714  1.00 93.02  ? 276 GLN A C   1 
ATOM   1554  O O   . GLN A 1 276 ? 123.053 94.372  96.023  1.00 95.58  ? 276 GLN A O   1 
ATOM   1555  C CB  . GLN A 1 276 ? 123.127 97.504  96.933  1.00 86.48  ? 276 GLN A CB  1 
ATOM   1556  C CG  . GLN A 1 276 ? 122.233 98.545  97.621  1.00 92.30  ? 276 GLN A CG  1 
ATOM   1557  C CD  . GLN A 1 276 ? 122.461 99.961  97.086  1.00 92.88  ? 276 GLN A CD  1 
ATOM   1558  O OE1 . GLN A 1 276 ? 123.158 100.201 96.111  1.00 92.50  ? 276 GLN A OE1 1 
ATOM   1559  N NE2 . GLN A 1 276 ? 121.874 100.963 97.698  1.00 89.68  ? 276 GLN A NE2 1 
ATOM   1560  N N   . MET A 1 277 ? 125.100 94.921  96.714  1.00 101.83 ? 277 MET A N   1 
ATOM   1561  C CA  . MET A 1 277 ? 125.756 93.834  95.969  1.00 97.73  ? 277 MET A CA  1 
ATOM   1562  C C   . MET A 1 277 ? 125.502 92.457  96.588  1.00 99.00  ? 277 MET A C   1 
ATOM   1563  O O   . MET A 1 277 ? 125.301 91.493  95.857  1.00 97.69  ? 277 MET A O   1 
ATOM   1564  C CB  . MET A 1 277 ? 127.260 94.093  95.826  1.00 98.08  ? 277 MET A CB  1 
ATOM   1565  C CG  . MET A 1 277 ? 127.518 95.097  94.704  1.00 100.62 ? 277 MET A CG  1 
ATOM   1566  S SD  . MET A 1 277 ? 129.250 95.317  94.231  1.00 103.42 ? 277 MET A SD  1 
ATOM   1567  C CE  . MET A 1 277 ? 129.759 96.502  95.495  1.00 99.26  ? 277 MET A CE  1 
ATOM   1568  N N   . GLY A 1 278 ? 125.397 92.343  97.909  1.00 101.70 ? 278 GLY A N   1 
ATOM   1569  C CA  . GLY A 1 278 ? 124.941 91.123  98.571  1.00 104.06 ? 278 GLY A CA  1 
ATOM   1570  C C   . GLY A 1 278 ? 123.570 90.643  98.090  1.00 100.65 ? 278 GLY A C   1 
ATOM   1571  O O   . GLY A 1 278 ? 123.372 89.444  97.935  1.00 98.30  ? 278 GLY A O   1 
ATOM   1572  N N   . ALA A 1 279 ? 122.648 91.546  97.747  1.00 101.03 ? 279 ALA A N   1 
ATOM   1573  C CA  . ALA A 1 279 ? 121.354 91.181  97.175  1.00 100.76 ? 279 ALA A CA  1 
ATOM   1574  C C   . ALA A 1 279 ? 121.446 90.615  95.744  1.00 104.13 ? 279 ALA A C   1 
ATOM   1575  O O   . ALA A 1 279 ? 120.535 89.902  95.325  1.00 103.28 ? 279 ALA A O   1 
ATOM   1576  C CB  . ALA A 1 279 ? 120.416 92.387  97.247  1.00 99.05  ? 279 ALA A CB  1 
ATOM   1577  N N   . ARG A 1 280 ? 122.530 90.883  94.993  1.00 108.06 ? 280 ARG A N   1 
ATOM   1578  C CA  . ARG A 1 280 ? 122.815 90.226  93.701  1.00 105.91 ? 280 ARG A CA  1 
ATOM   1579  C C   . ARG A 1 280 ? 123.574 88.910  93.865  1.00 104.67 ? 280 ARG A C   1 
ATOM   1580  O O   . ARG A 1 280 ? 123.204 87.898  93.278  1.00 99.73  ? 280 ARG A O   1 
ATOM   1581  C CB  . ARG A 1 280 ? 123.632 91.136  92.769  1.00 104.87 ? 280 ARG A CB  1 
ATOM   1582  C CG  . ARG A 1 280 ? 123.041 92.528  92.536  1.00 102.45 ? 280 ARG A CG  1 
ATOM   1583  C CD  . ARG A 1 280 ? 123.591 93.157  91.249  1.00 103.35 ? 280 ARG A CD  1 
ATOM   1584  N NE  . ARG A 1 280 ? 125.068 93.205  91.192  1.00 107.39 ? 280 ARG A NE  1 
ATOM   1585  C CZ  . ARG A 1 280 ? 125.843 94.254  91.360  1.00 110.61 ? 280 ARG A CZ  1 
ATOM   1586  N NH1 . ARG A 1 280 ? 127.126 94.178  91.163  1.00 107.61 ? 280 ARG A NH1 1 
ATOM   1587  N NH2 . ARG A 1 280 ? 125.368 95.405  91.735  1.00 106.77 ? 280 ARG A NH2 1 
ATOM   1588  N N   . LEU A 1 281 ? 124.662 88.946  94.631  1.00 109.29 ? 281 LEU A N   1 
ATOM   1589  C CA  . LEU A 1 281 ? 125.684 87.897  94.708  1.00 108.79 ? 281 LEU A CA  1 
ATOM   1590  C C   . LEU A 1 281 ? 125.359 86.798  95.728  1.00 107.71 ? 281 LEU A C   1 
ATOM   1591  O O   . LEU A 1 281 ? 125.746 85.648  95.539  1.00 105.76 ? 281 LEU A O   1 
ATOM   1592  C CB  . LEU A 1 281 ? 127.024 88.566  95.062  1.00 108.14 ? 281 LEU A CB  1 
ATOM   1593  C CG  . LEU A 1 281 ? 127.499 89.630  94.061  1.00 106.33 ? 281 LEU A CG  1 
ATOM   1594  C CD1 . LEU A 1 281 ? 128.691 90.368  94.642  1.00 111.03 ? 281 LEU A CD1 1 
ATOM   1595  C CD2 . LEU A 1 281 ? 127.900 89.027  92.722  1.00 100.50 ? 281 LEU A CD2 1 
ATOM   1596  N N   . CYS A 1 282 ? 124.632 87.145  96.792  1.00 109.82 ? 282 CYS A N   1 
ATOM   1597  C CA  . CYS A 1 282 ? 124.269 86.275  97.909  1.00 109.67 ? 282 CYS A CA  1 
ATOM   1598  C C   . CYS A 1 282 ? 122.764 86.417  98.239  1.00 112.90 ? 282 CYS A C   1 
ATOM   1599  O O   . CYS A 1 282 ? 122.418 86.730  99.379  1.00 115.41 ? 282 CYS A O   1 
ATOM   1600  C CB  . CYS A 1 282 ? 125.145 86.635  99.125  1.00 110.02 ? 282 CYS A CB  1 
ATOM   1601  S SG  . CYS A 1 282 ? 126.915 86.541  98.772  1.00 117.30 ? 282 CYS A SG  1 
ATOM   1602  N N   . PRO A 1 283 ? 121.837 86.241  97.277  1.00 109.16 ? 283 PRO A N   1 
ATOM   1603  C CA  . PRO A 1 283 ? 120.473 86.764  97.386  1.00 108.02 ? 283 PRO A CA  1 
ATOM   1604  C C   . PRO A 1 283 ? 119.660 86.150  98.536  1.00 107.83 ? 283 PRO A C   1 
ATOM   1605  O O   . PRO A 1 283 ? 118.780 86.807  99.091  1.00 104.75 ? 283 PRO A O   1 
ATOM   1606  C CB  . PRO A 1 283 ? 119.830 86.480  96.025  1.00 107.57 ? 283 PRO A CB  1 
ATOM   1607  C CG  . PRO A 1 283 ? 120.630 85.303  95.469  1.00 107.46 ? 283 PRO A CG  1 
ATOM   1608  C CD  . PRO A 1 283 ? 122.033 85.566  96.003  1.00 107.52 ? 283 PRO A CD  1 
ATOM   1609  N N   . THR A 1 284 ? 119.953 84.906  98.910  1.00 110.82 ? 284 THR A N   1 
ATOM   1610  C CA  . THR A 1 284 ? 119.323 84.196  100.037 1.00 112.18 ? 284 THR A CA  1 
ATOM   1611  C C   . THR A 1 284 ? 119.950 84.506  101.403 1.00 108.37 ? 284 THR A C   1 
ATOM   1612  O O   . THR A 1 284 ? 119.439 84.040  102.423 1.00 104.00 ? 284 THR A O   1 
ATOM   1613  C CB  . THR A 1 284 ? 119.366 82.683  99.795  1.00 111.89 ? 284 THR A CB  1 
ATOM   1614  O OG1 . THR A 1 284 ? 120.695 82.255  99.599  1.00 111.16 ? 284 THR A OG1 1 
ATOM   1615  C CG2 . THR A 1 284 ? 118.565 82.269  98.565  1.00 106.16 ? 284 THR A CG2 1 
ATOM   1616  N N   . VAL A 1 285 ? 121.044 85.270  101.470 1.00 104.31 ? 285 VAL A N   1 
ATOM   1617  C CA  . VAL A 1 285 ? 121.832 85.468  102.695 1.00 103.96 ? 285 VAL A CA  1 
ATOM   1618  C C   . VAL A 1 285 ? 121.562 86.839  103.308 1.00 102.74 ? 285 VAL A C   1 
ATOM   1619  O O   . VAL A 1 285 ? 121.709 87.878  102.666 1.00 101.06 ? 285 VAL A O   1 
ATOM   1620  C CB  . VAL A 1 285 ? 123.342 85.287  102.449 1.00 103.27 ? 285 VAL A CB  1 
ATOM   1621  C CG1 . VAL A 1 285 ? 124.110 85.311  103.774 1.00 102.64 ? 285 VAL A CG1 1 
ATOM   1622  C CG2 . VAL A 1 285 ? 123.656 83.964  101.747 1.00 101.78 ? 285 VAL A CG2 1 
ATOM   1623  N N   . GLN A 1 286 ? 121.205 86.847  104.589 1.00 101.29 ? 286 GLN A N   1 
ATOM   1624  C CA  . GLN A 1 286 ? 121.022 88.055  105.389 1.00 98.47  ? 286 GLN A CA  1 
ATOM   1625  C C   . GLN A 1 286 ? 122.374 88.498  105.974 1.00 100.27 ? 286 GLN A C   1 
ATOM   1626  O O   . GLN A 1 286 ? 122.723 88.113  107.088 1.00 103.37 ? 286 GLN A O   1 
ATOM   1627  C CB  . GLN A 1 286 ? 119.977 87.762  106.480 1.00 99.06  ? 286 GLN A CB  1 
ATOM   1628  C CG  . GLN A 1 286 ? 118.582 87.380  105.953 1.00 100.75 ? 286 GLN A CG  1 
ATOM   1629  C CD  . GLN A 1 286 ? 117.774 88.578  105.478 1.00 104.13 ? 286 GLN A CD  1 
ATOM   1630  O OE1 . GLN A 1 286 ? 117.603 88.825  104.293 1.00 99.57  ? 286 GLN A OE1 1 
ATOM   1631  N NE2 . GLN A 1 286 ? 117.243 89.371  106.377 1.00 105.48 ? 286 GLN A NE2 1 
ATOM   1632  N N   . LEU A 1 287 ? 123.151 89.292  105.229 1.00 90.56  ? 287 LEU A N   1 
ATOM   1633  C CA  . LEU A 1 287 ? 124.533 89.657  105.591 1.00 82.75  ? 287 LEU A CA  1 
ATOM   1634  C C   . LEU A 1 287 ? 124.653 90.398  106.927 1.00 85.31  ? 287 LEU A C   1 
ATOM   1635  O O   . LEU A 1 287 ? 125.659 90.282  107.618 1.00 90.62  ? 287 LEU A O   1 
ATOM   1636  C CB  . LEU A 1 287 ? 125.168 90.518  104.483 1.00 82.54  ? 287 LEU A CB  1 
ATOM   1637  C CG  . LEU A 1 287 ? 125.360 89.853  103.115 1.00 86.95  ? 287 LEU A CG  1 
ATOM   1638  C CD1 . LEU A 1 287 ? 126.025 90.851  102.180 1.00 85.35  ? 287 LEU A CD1 1 
ATOM   1639  C CD2 . LEU A 1 287 ? 126.246 88.619  103.178 1.00 89.02  ? 287 LEU A CD2 1 
ATOM   1640  N N   . GLU A 1 288 ? 123.605 91.125  107.296 1.00 85.61  ? 288 GLU A N   1 
ATOM   1641  C CA  . GLU A 1 288 ? 123.485 91.821  108.570 1.00 84.13  ? 288 GLU A CA  1 
ATOM   1642  C C   . GLU A 1 288 ? 122.931 90.953  109.703 1.00 85.48  ? 288 GLU A C   1 
ATOM   1643  O O   . GLU A 1 288 ? 122.779 91.437  110.815 1.00 93.26  ? 288 GLU A O   1 
ATOM   1644  C CB  . GLU A 1 288 ? 122.604 93.050  108.390 1.00 85.80  ? 288 GLU A CB  1 
ATOM   1645  C CG  . GLU A 1 288 ? 123.184 94.022  107.374 1.00 85.92  ? 288 GLU A CG  1 
ATOM   1646  C CD  . GLU A 1 288 ? 122.381 95.314  107.389 1.00 90.38  ? 288 GLU A CD  1 
ATOM   1647  O OE1 . GLU A 1 288 ? 121.140 95.250  107.283 1.00 97.16  ? 288 GLU A OE1 1 
ATOM   1648  O OE2 . GLU A 1 288 ? 122.978 96.398  107.537 1.00 81.12  ? 288 GLU A OE2 1 
ATOM   1649  N N   . GLU A 1 289 ? 122.632 89.679  109.456 1.00 86.88  ? 289 GLU A N   1 
ATOM   1650  C CA  . GLU A 1 289 ? 122.328 88.689  110.492 1.00 87.36  ? 289 GLU A CA  1 
ATOM   1651  C C   . GLU A 1 289 ? 123.522 87.763  110.771 1.00 92.68  ? 289 GLU A C   1 
ATOM   1652  O O   . GLU A 1 289 ? 123.456 86.916  111.662 1.00 95.31  ? 289 GLU A O   1 
ATOM   1653  C CB  . GLU A 1 289 ? 121.060 87.907  110.128 1.00 91.23  ? 289 GLU A CB  1 
ATOM   1654  C CG  . GLU A 1 289 ? 119.830 88.826  110.043 1.00 95.29  ? 289 GLU A CG  1 
ATOM   1655  C CD  . GLU A 1 289 ? 118.534 88.076  109.696 1.00 96.28  ? 289 GLU A CD  1 
ATOM   1656  O OE1 . GLU A 1 289 ? 118.368 86.900  110.094 1.00 96.65  ? 289 GLU A OE1 1 
ATOM   1657  O OE2 . GLU A 1 289 ? 117.661 88.680  109.035 1.00 93.96  ? 289 GLU A OE2 1 
ATOM   1658  N N   . ILE A 1 290 ? 124.636 87.927  110.051 1.00 88.19  ? 290 ILE A N   1 
ATOM   1659  C CA  . ILE A 1 290 ? 125.896 87.226  110.312 1.00 80.59  ? 290 ILE A CA  1 
ATOM   1660  C C   . ILE A 1 290 ? 126.511 87.791  111.592 1.00 82.23  ? 290 ILE A C   1 
ATOM   1661  O O   . ILE A 1 290 ? 126.669 89.000  111.729 1.00 83.87  ? 290 ILE A O   1 
ATOM   1662  C CB  . ILE A 1 290 ? 126.859 87.321  109.108 1.00 80.69  ? 290 ILE A CB  1 
ATOM   1663  C CG1 . ILE A 1 290 ? 126.225 86.711  107.842 1.00 82.31  ? 290 ILE A CG1 1 
ATOM   1664  C CG2 . ILE A 1 290 ? 128.174 86.600  109.444 1.00 87.94  ? 290 ILE A CG2 1 
ATOM   1665  C CD1 . ILE A 1 290 ? 127.064 86.840  106.571 1.00 85.11  ? 290 ILE A CD1 1 
ATOM   1666  N N   . SER A 1 291 ? 126.865 86.920  112.532 1.00 81.42  ? 291 SER A N   1 
ATOM   1667  C CA  . SER A 1 291 ? 127.411 87.282  113.845 1.00 76.58  ? 291 SER A CA  1 
ATOM   1668  C C   . SER A 1 291 ? 128.911 87.015  113.924 1.00 83.41  ? 291 SER A C   1 
ATOM   1669  O O   . SER A 1 291 ? 129.369 85.939  113.541 1.00 81.95  ? 291 SER A O   1 
ATOM   1670  C CB  . SER A 1 291 ? 126.705 86.488  114.942 1.00 77.14  ? 291 SER A CB  1 
ATOM   1671  O OG  . SER A 1 291 ? 125.328 86.799  114.971 1.00 82.42  ? 291 SER A OG  1 
ATOM   1672  N N   . ASN A 1 292 ? 129.692 87.963  114.438 1.00 75.85  ? 292 ASN A N   1 
ATOM   1673  C CA  . ASN A 1 292 ? 131.106 87.730  114.735 1.00 70.44  ? 292 ASN A CA  1 
ATOM   1674  C C   . ASN A 1 292 ? 131.285 86.828  115.980 1.00 73.49  ? 292 ASN A C   1 
ATOM   1675  O O   . ASN A 1 292 ? 130.311 86.359  116.566 1.00 78.73  ? 292 ASN A O   1 
ATOM   1676  C CB  . ASN A 1 292 ? 131.823 89.089  114.795 1.00 70.97  ? 292 ASN A CB  1 
ATOM   1677  C CG  . ASN A 1 292 ? 131.550 89.926  116.019 1.00 67.21  ? 292 ASN A CG  1 
ATOM   1678  O OD1 . ASN A 1 292 ? 130.902 89.516  116.964 1.00 77.27  ? 292 ASN A OD1 1 
ATOM   1679  N ND2 . ASN A 1 292 ? 132.074 91.118  116.056 1.00 67.54  ? 292 ASN A ND2 1 
ATOM   1680  N N   . HIS A 1 293 ? 132.517 86.566  116.426 1.00 86.51  ? 293 HIS A N   1 
ATOM   1681  C CA  . HIS A 1 293 ? 132.764 85.685  117.578 1.00 86.22  ? 293 HIS A CA  1 
ATOM   1682  C C   . HIS A 1 293 ? 132.279 86.247  118.923 1.00 87.87  ? 293 HIS A C   1 
ATOM   1683  O O   . HIS A 1 293 ? 132.154 85.490  119.882 1.00 92.93  ? 293 HIS A O   1 
ATOM   1684  C CB  . HIS A 1 293 ? 134.252 85.332  117.650 1.00 81.07  ? 293 HIS A CB  1 
ATOM   1685  C CG  . HIS A 1 293 ? 134.794 84.537  116.488 1.00 85.83  ? 293 HIS A CG  1 
ATOM   1686  N ND1 . HIS A 1 293 ? 136.142 84.256  116.298 1.00 92.29  ? 293 HIS A ND1 1 
ATOM   1687  C CD2 . HIS A 1 293 ? 134.081 83.920  115.500 1.00 85.13  ? 293 HIS A CD2 1 
ATOM   1688  C CE1 . HIS A 1 293 ? 136.219 83.500  115.191 1.00 88.68  ? 293 HIS A CE1 1 
ATOM   1689  N NE2 . HIS A 1 293 ? 134.995 83.281  114.696 1.00 85.15  ? 293 HIS A NE2 1 
ATOM   1690  N N   . GLN A 1 294 ? 131.957 87.540  119.011 1.00 81.88  ? 294 GLN A N   1 
ATOM   1691  C CA  . GLN A 1 294 ? 131.267 88.139  120.161 1.00 82.12  ? 294 GLN A CA  1 
ATOM   1692  C C   . GLN A 1 294 ? 129.732 88.042  120.064 1.00 87.80  ? 294 GLN A C   1 
ATOM   1693  O O   . GLN A 1 294 ? 129.025 88.562  120.925 1.00 85.59  ? 294 GLN A O   1 
ATOM   1694  C CB  . GLN A 1 294 ? 131.700 89.600  120.347 1.00 84.26  ? 294 GLN A CB  1 
ATOM   1695  C CG  . GLN A 1 294 ? 133.212 89.759  120.523 1.00 88.36  ? 294 GLN A CG  1 
ATOM   1696  C CD  . GLN A 1 294 ? 133.630 91.132  121.046 1.00 92.26  ? 294 GLN A CD  1 
ATOM   1697  O OE1 . GLN A 1 294 ? 132.849 91.910  121.581 1.00 90.39  ? 294 GLN A OE1 1 
ATOM   1698  N NE2 . GLN A 1 294 ? 134.888 91.482  120.934 1.00 87.52  ? 294 GLN A NE2 1 
ATOM   1699  N N   . GLY A 1 295 ? 129.193 87.409  119.021 1.00 84.54  ? 295 GLY A N   1 
ATOM   1700  C CA  . GLY A 1 295 ? 127.756 87.298  118.769 1.00 79.75  ? 295 GLY A CA  1 
ATOM   1701  C C   . GLY A 1 295 ? 127.113 88.562  118.195 1.00 83.12  ? 295 GLY A C   1 
ATOM   1702  O O   . GLY A 1 295 ? 125.892 88.677  118.191 1.00 90.54  ? 295 GLY A O   1 
ATOM   1703  N N   . LEU A 1 296 ? 127.904 89.527  117.726 1.00 73.54  ? 296 LEU A N   1 
ATOM   1704  C CA  . LEU A 1 296 ? 127.415 90.820  117.256 1.00 66.85  ? 296 LEU A CA  1 
ATOM   1705  C C   . LEU A 1 296 ? 127.215 90.800  115.741 1.00 71.72  ? 296 LEU A C   1 
ATOM   1706  O O   . LEU A 1 296 ? 128.105 90.430  114.982 1.00 75.19  ? 296 LEU A O   1 
ATOM   1707  C CB  . LEU A 1 296 ? 128.391 91.941  117.651 1.00 66.27  ? 296 LEU A CB  1 
ATOM   1708  C CG  . LEU A 1 296 ? 128.689 92.041  119.151 1.00 67.99  ? 296 LEU A CG  1 
ATOM   1709  C CD1 . LEU A 1 296 ? 129.841 92.998  119.388 1.00 71.42  ? 296 LEU A CD1 1 
ATOM   1710  C CD2 . LEU A 1 296 ? 127.509 92.560  119.952 1.00 71.30  ? 296 LEU A CD2 1 
ATOM   1711  N N   . THR A 1 297 ? 126.051 91.246  115.290 1.00 73.82  ? 297 THR A N   1 
ATOM   1712  C CA  . THR A 1 297 ? 125.808 91.670  113.911 1.00 64.06  ? 297 THR A CA  1 
ATOM   1713  C C   . THR A 1 297 ? 126.406 93.063  113.670 1.00 63.74  ? 297 THR A C   1 
ATOM   1714  O O   . THR A 1 297 ? 126.741 93.746  114.637 1.00 66.69  ? 297 THR A O   1 
ATOM   1715  C CB  . THR A 1 297 ? 124.304 91.680  113.644 1.00 60.71  ? 297 THR A CB  1 
ATOM   1716  O OG1 . THR A 1 297 ? 123.642 92.562  114.512 1.00 69.55  ? 297 THR A OG1 1 
ATOM   1717  C CG2 . THR A 1 297 ? 123.668 90.310  113.827 1.00 58.48  ? 297 THR A CG2 1 
ATOM   1718  N N   . PRO A 1 298 ? 126.529 93.555  112.424 1.00 52.09  ? 298 PRO A N   1 
ATOM   1719  C CA  . PRO A 1 298 ? 127.027 94.901  112.157 1.00 52.09  ? 298 PRO A CA  1 
ATOM   1720  C C   . PRO A 1 298 ? 126.289 96.028  112.907 1.00 50.98  ? 298 PRO A C   1 
ATOM   1721  O O   . PRO A 1 298 ? 126.942 96.917  113.439 1.00 56.21  ? 298 PRO A O   1 
ATOM   1722  C CB  . PRO A 1 298 ? 126.923 95.065  110.644 1.00 61.02  ? 298 PRO A CB  1 
ATOM   1723  C CG  . PRO A 1 298 ? 127.046 93.645  110.118 1.00 54.05  ? 298 PRO A CG  1 
ATOM   1724  C CD  . PRO A 1 298 ? 126.326 92.832  111.181 1.00 57.41  ? 298 PRO A CD  1 
ATOM   1725  N N   . LEU A 1 299 ? 124.958 95.980  113.036 1.00 54.58  ? 299 LEU A N   1 
ATOM   1726  C CA  . LEU A 1 299 ? 124.182 96.967  113.803 1.00 57.38  ? 299 LEU A CA  1 
ATOM   1727  C C   . LEU A 1 299 ? 124.500 96.922  115.303 1.00 67.24  ? 299 LEU A C   1 
ATOM   1728  O O   . LEU A 1 299 ? 124.695 97.959  115.931 1.00 69.74  ? 299 LEU A O   1 
ATOM   1729  C CB  . LEU A 1 299 ? 122.677 96.752  113.552 1.00 56.18  ? 299 LEU A CB  1 
ATOM   1730  C CG  . LEU A 1 299 ? 121.753 97.709  114.338 1.00 49.48  ? 299 LEU A CG  1 
ATOM   1731  C CD1 . LEU A 1 299 ? 121.927 99.161  113.933 1.00 57.77  ? 299 LEU A CD1 1 
ATOM   1732  C CD2 . LEU A 1 299 ? 120.298 97.342  114.122 1.00 61.32  ? 299 LEU A CD2 1 
ATOM   1733  N N   . LYS A 1 300 ? 124.586 95.723  115.886 1.00 70.45  ? 300 LYS A N   1 
ATOM   1734  C CA  . LYS A 1 300 ? 124.944 95.531  117.298 1.00 55.05  ? 300 LYS A CA  1 
ATOM   1735  C C   . LYS A 1 300 ? 126.385 95.949  117.584 1.00 60.99  ? 300 LYS A C   1 
ATOM   1736  O O   . LYS A 1 300 ? 126.655 96.535  118.622 1.00 74.73  ? 300 LYS A O   1 
ATOM   1737  C CB  . LYS A 1 300 ? 124.727 94.068  117.691 1.00 62.06  ? 300 LYS A CB  1 
ATOM   1738  C CG  . LYS A 1 300 ? 123.251 93.676  117.764 1.00 55.44  ? 300 LYS A CG  1 
ATOM   1739  C CD  . LYS A 1 300 ? 123.119 92.245  118.282 1.00 57.92  ? 300 LYS A CD  1 
ATOM   1740  C CE  . LYS A 1 300 ? 121.668 91.787  118.211 1.00 64.44  ? 300 LYS A CE  1 
ATOM   1741  N NZ  . LYS A 1 300 ? 121.483 90.458  118.836 1.00 66.28  ? 300 LYS A NZ  1 
ATOM   1742  N N   . LEU A 1 301 ? 127.309 95.702  116.662 1.00 60.57  ? 301 LEU A N   1 
ATOM   1743  C CA  . LEU A 1 301 ? 128.687 96.167  116.757 1.00 65.04  ? 301 LEU A CA  1 
ATOM   1744  C C   . LEU A 1 301 ? 128.789 97.694  116.683 1.00 67.85  ? 301 LEU A C   1 
ATOM   1745  O O   . LEU A 1 301 ? 129.557 98.283  117.432 1.00 72.17  ? 301 LEU A O   1 
ATOM   1746  C CB  . LEU A 1 301 ? 129.511 95.471  115.665 1.00 60.38  ? 301 LEU A CB  1 
ATOM   1747  C CG  . LEU A 1 301 ? 131.002 95.818  115.680 1.00 50.36  ? 301 LEU A CG  1 
ATOM   1748  C CD1 . LEU A 1 301 ? 131.703 95.312  116.931 1.00 57.87  ? 301 LEU A CD1 1 
ATOM   1749  C CD2 . LEU A 1 301 ? 131.675 95.172  114.486 1.00 56.24  ? 301 LEU A CD2 1 
ATOM   1750  N N   . ALA A 1 302 ? 127.987 98.366  115.860 1.00 64.16  ? 302 ALA A N   1 
ATOM   1751  C CA  . ALA A 1 302 ? 127.973 99.824  115.798 1.00 46.81  ? 302 ALA A CA  1 
ATOM   1752  C C   . ALA A 1 302 ? 127.510 100.469 117.117 1.00 62.83  ? 302 ALA A C   1 
ATOM   1753  O O   . ALA A 1 302 ? 128.022 101.519 117.484 1.00 72.14  ? 302 ALA A O   1 
ATOM   1754  C CB  . ALA A 1 302 ? 127.117 100.245 114.604 1.00 44.06  ? 302 ALA A CB  1 
ATOM   1755  N N   . ALA A 1 303 ? 126.610 99.819  117.861 1.00 69.16  ? 303 ALA A N   1 
ATOM   1756  C CA  . ALA A 1 303 ? 126.176 100.196 119.202 1.00 57.75  ? 303 ALA A CA  1 
ATOM   1757  C C   . ALA A 1 303 ? 127.251 99.952  120.273 1.00 68.14  ? 303 ALA A C   1 
ATOM   1758  O O   . ALA A 1 303 ? 127.536 100.846 121.065 1.00 73.68  ? 303 ALA A O   1 
ATOM   1759  C CB  . ALA A 1 303 ? 124.899 99.421  119.514 1.00 58.19  ? 303 ALA A CB  1 
ATOM   1760  N N   . LYS A 1 304 ? 127.905 98.785  120.270 1.00 68.36  ? 304 LYS A N   1 
ATOM   1761  C CA  . LYS A 1 304 ? 128.952 98.456  121.243 1.00 58.28  ? 304 LYS A CA  1 
ATOM   1762  C C   . LYS A 1 304 ? 130.191 99.335  121.087 1.00 67.84  ? 304 LYS A C   1 
ATOM   1763  O O   . LYS A 1 304 ? 130.743 99.810  122.073 1.00 72.79  ? 304 LYS A O   1 
ATOM   1764  C CB  . LYS A 1 304 ? 129.296 96.969  121.140 1.00 60.71  ? 304 LYS A CB  1 
ATOM   1765  C CG  . LYS A 1 304 ? 130.122 96.540  122.352 1.00 76.65  ? 304 LYS A CG  1 
ATOM   1766  C CD  . LYS A 1 304 ? 130.391 95.042  122.339 1.00 77.53  ? 304 LYS A CD  1 
ATOM   1767  C CE  . LYS A 1 304 ? 131.164 94.628  123.590 1.00 75.00  ? 304 LYS A CE  1 
ATOM   1768  N NZ  . LYS A 1 304 ? 131.376 93.162  123.626 1.00 79.10  ? 304 LYS A NZ  1 
ATOM   1769  N N   . GLU A 1 305 ? 130.597 99.605  119.854 1.00 76.41  ? 305 GLU A N   1 
ATOM   1770  C CA  . GLU A 1 305 ? 131.707 100.503 119.521 1.00 71.04  ? 305 GLU A CA  1 
ATOM   1771  C C   . GLU A 1 305 ? 131.314 101.993 119.533 1.00 72.89  ? 305 GLU A C   1 
ATOM   1772  O O   . GLU A 1 305 ? 132.177 102.855 119.407 1.00 74.73  ? 305 GLU A O   1 
ATOM   1773  C CB  . GLU A 1 305 ? 132.301 100.083 118.170 1.00 67.51  ? 305 GLU A CB  1 
ATOM   1774  C CG  . GLU A 1 305 ? 132.878 98.661  118.168 1.00 72.79  ? 305 GLU A CG  1 
ATOM   1775  C CD  . GLU A 1 305 ? 134.047 98.481  119.149 1.00 81.16  ? 305 GLU A CD  1 
ATOM   1776  O OE1 . GLU A 1 305 ? 134.960 99.337  119.168 1.00 83.44  ? 305 GLU A OE1 1 
ATOM   1777  O OE2 . GLU A 1 305 ? 134.068 97.476  119.895 1.00 80.80  ? 305 GLU A OE2 1 
ATOM   1778  N N   . GLY A 1 306 ? 130.031 102.323 119.703 1.00 64.84  ? 306 GLY A N   1 
ATOM   1779  C CA  . GLY A 1 306 ? 129.549 103.696 119.855 1.00 60.32  ? 306 GLY A CA  1 
ATOM   1780  C C   . GLY A 1 306 ? 129.625 104.552 118.600 1.00 61.33  ? 306 GLY A C   1 
ATOM   1781  O O   . GLY A 1 306 ? 129.807 105.761 118.696 1.00 70.80  ? 306 GLY A O   1 
ATOM   1782  N N   . LYS A 1 307 ? 129.545 103.954 117.414 1.00 67.75  ? 307 LYS A N   1 
ATOM   1783  C CA  . LYS A 1 307 ? 129.724 104.634 116.126 1.00 71.25  ? 307 LYS A CA  1 
ATOM   1784  C C   . LYS A 1 307 ? 128.422 105.285 115.665 1.00 76.03  ? 307 LYS A C   1 
ATOM   1785  O O   . LYS A 1 307 ? 127.742 104.729 114.813 1.00 74.27  ? 307 LYS A O   1 
ATOM   1786  C CB  . LYS A 1 307 ? 130.274 103.641 115.087 1.00 61.65  ? 307 LYS A CB  1 
ATOM   1787  C CG  . LYS A 1 307 ? 131.547 102.889 115.478 1.00 69.65  ? 307 LYS A CG  1 
ATOM   1788  C CD  . LYS A 1 307 ? 132.691 103.833 115.856 1.00 70.03  ? 307 LYS A CD  1 
ATOM   1789  C CE  . LYS A 1 307 ? 133.996 103.078 116.095 1.00 67.05  ? 307 LYS A CE  1 
ATOM   1790  N NZ  . LYS A 1 307 ? 134.544 102.535 114.836 1.00 70.21  ? 307 LYS A NZ  1 
ATOM   1791  N N   . ILE A 1 308 ? 128.036 106.438 116.210 1.00 79.20  ? 308 ILE A N   1 
ATOM   1792  C CA  . ILE A 1 308 ? 126.676 106.987 116.029 1.00 69.61  ? 308 ILE A CA  1 
ATOM   1793  C C   . ILE A 1 308 ? 126.290 107.155 114.557 1.00 69.38  ? 308 ILE A C   1 
ATOM   1794  O O   . ILE A 1 308 ? 125.161 106.867 114.197 1.00 78.62  ? 308 ILE A O   1 
ATOM   1795  C CB  . ILE A 1 308 ? 126.470 108.336 116.753 1.00 73.81  ? 308 ILE A CB  1 
ATOM   1796  C CG1 . ILE A 1 308 ? 126.889 108.315 118.227 1.00 75.52  ? 308 ILE A CG1 1 
ATOM   1797  C CG2 . ILE A 1 308 ? 124.990 108.760 116.688 1.00 73.72  ? 308 ILE A CG2 1 
ATOM   1798  C CD1 . ILE A 1 308 ? 127.196 109.729 118.725 1.00 82.24  ? 308 ILE A CD1 1 
ATOM   1799  N N   . GLU A 1 309 ? 127.193 107.604 113.687 1.00 77.67  ? 309 GLU A N   1 
ATOM   1800  C CA  . GLU A 1 309 ? 126.831 107.943 112.306 1.00 77.85  ? 309 GLU A CA  1 
ATOM   1801  C C   . GLU A 1 309 ? 126.453 106.723 111.462 1.00 76.16  ? 309 GLU A C   1 
ATOM   1802  O O   . GLU A 1 309 ? 125.404 106.713 110.823 1.00 76.94  ? 309 GLU A O   1 
ATOM   1803  C CB  . GLU A 1 309 ? 127.976 108.706 111.627 1.00 82.19  ? 309 GLU A CB  1 
ATOM   1804  C CG  . GLU A 1 309 ? 128.424 109.988 112.344 1.00 85.28  ? 309 GLU A CG  1 
ATOM   1805  C CD  . GLU A 1 309 ? 127.296 111.002 112.580 1.00 87.52  ? 309 GLU A CD  1 
ATOM   1806  O OE1 . GLU A 1 309 ? 126.263 110.956 111.873 1.00 85.71  ? 309 GLU A OE1 1 
ATOM   1807  O OE2 . GLU A 1 309 ? 127.427 111.859 113.481 1.00 85.86  ? 309 GLU A OE2 1 
ATOM   1808  N N   . ILE A 1 310 ? 127.268 105.667 111.477 1.00 68.10  ? 310 ILE A N   1 
ATOM   1809  C CA  . ILE A 1 310 ? 126.932 104.403 110.816 1.00 64.45  ? 310 ILE A CA  1 
ATOM   1810  C C   . ILE A 1 310 ? 125.811 103.663 111.551 1.00 70.81  ? 310 ILE A C   1 
ATOM   1811  O O   . ILE A 1 310 ? 124.976 103.047 110.900 1.00 72.43  ? 310 ILE A O   1 
ATOM   1812  C CB  . ILE A 1 310 ? 128.192 103.547 110.562 1.00 65.48  ? 310 ILE A CB  1 
ATOM   1813  C CG1 . ILE A 1 310 ? 127.935 102.268 109.737 1.00 72.32  ? 310 ILE A CG1 1 
ATOM   1814  C CG2 . ILE A 1 310 ? 128.882 103.130 111.864 1.00 67.34  ? 310 ILE A CG2 1 
ATOM   1815  C CD1 . ILE A 1 310 ? 127.379 102.520 108.332 1.00 75.07  ? 310 ILE A CD1 1 
ATOM   1816  N N   . PHE A 1 311 ? 125.711 103.765 112.881 1.00 72.85  ? 311 PHE A N   1 
ATOM   1817  C CA  . PHE A 1 311 ? 124.601 103.208 113.658 1.00 60.87  ? 311 PHE A CA  1 
ATOM   1818  C C   . PHE A 1 311 ? 123.257 103.814 113.244 1.00 63.63  ? 311 PHE A C   1 
ATOM   1819  O O   . PHE A 1 311 ? 122.364 103.091 112.823 1.00 66.20  ? 311 PHE A O   1 
ATOM   1820  C CB  . PHE A 1 311 ? 124.867 103.423 115.151 1.00 54.92  ? 311 PHE A CB  1 
ATOM   1821  C CG  . PHE A 1 311 ? 123.747 102.948 116.045 1.00 62.62  ? 311 PHE A CG  1 
ATOM   1822  C CD1 . PHE A 1 311 ? 123.462 101.577 116.130 1.00 62.92  ? 311 PHE A CD1 1 
ATOM   1823  C CD2 . PHE A 1 311 ? 122.976 103.867 116.777 1.00 63.78  ? 311 PHE A CD2 1 
ATOM   1824  C CE1 . PHE A 1 311 ? 122.403 101.125 116.919 1.00 58.24  ? 311 PHE A CE1 1 
ATOM   1825  C CE2 . PHE A 1 311 ? 121.912 103.417 117.566 1.00 63.66  ? 311 PHE A CE2 1 
ATOM   1826  C CZ  . PHE A 1 311 ? 121.624 102.049 117.627 1.00 65.50  ? 311 PHE A CZ  1 
ATOM   1827  N N   . ARG A 1 312 ? 123.139 105.147 113.275 1.00 66.67  ? 312 ARG A N   1 
ATOM   1828  C CA  . ARG A 1 312 ? 121.982 105.913 112.805 1.00 58.49  ? 312 ARG A CA  1 
ATOM   1829  C C   . ARG A 1 312 ? 121.619 105.559 111.378 1.00 67.40  ? 312 ARG A C   1 
ATOM   1830  O O   . ARG A 1 312 ? 120.448 105.339 111.097 1.00 75.74  ? 312 ARG A O   1 
ATOM   1831  C CB  . ARG A 1 312 ? 122.302 107.408 112.929 1.00 63.19  ? 312 ARG A CB  1 
ATOM   1832  C CG  . ARG A 1 312 ? 121.247 108.308 112.275 1.00 65.41  ? 312 ARG A CG  1 
ATOM   1833  C CD  . ARG A 1 312 ? 121.278 109.741 112.798 1.00 73.05  ? 312 ARG A CD  1 
ATOM   1834  N NE  . ARG A 1 312 ? 122.611 110.367 112.753 1.00 78.77  ? 312 ARG A NE  1 
ATOM   1835  C CZ  . ARG A 1 312 ? 122.966 111.444 113.429 1.00 79.62  ? 312 ARG A CZ  1 
ATOM   1836  N NH1 . ARG A 1 312 ? 124.160 111.933 113.330 1.00 74.59  ? 312 ARG A NH1 1 
ATOM   1837  N NH2 . ARG A 1 312 ? 122.140 112.070 114.212 1.00 77.07  ? 312 ARG A NH2 1 
ATOM   1838  N N   . HIS A 1 313 ? 122.596 105.481 110.480 1.00 64.93  ? 313 HIS A N   1 
ATOM   1839  C CA  . HIS A 1 313 ? 122.334 105.126 109.095 1.00 53.76  ? 313 HIS A CA  1 
ATOM   1840  C C   . HIS A 1 313 ? 121.729 103.736 108.962 1.00 62.15  ? 313 HIS A C   1 
ATOM   1841  O O   . HIS A 1 313 ? 120.666 103.621 108.371 1.00 75.48  ? 313 HIS A O   1 
ATOM   1842  C CB  . HIS A 1 313 ? 123.598 105.251 108.259 1.00 67.91  ? 313 HIS A CB  1 
ATOM   1843  C CG  . HIS A 1 313 ? 123.332 104.822 106.843 1.00 74.71  ? 313 HIS A CG  1 
ATOM   1844  N ND1 . HIS A 1 313 ? 122.575 105.539 105.916 1.00 67.33  ? 313 HIS A ND1 1 
ATOM   1845  C CD2 . HIS A 1 313 ? 123.664 103.613 106.313 1.00 68.19  ? 313 HIS A CD2 1 
ATOM   1846  C CE1 . HIS A 1 313 ? 122.480 104.744 104.840 1.00 65.28  ? 313 HIS A CE1 1 
ATOM   1847  N NE2 . HIS A 1 313 ? 123.115 103.586 105.058 1.00 60.32  ? 313 HIS A NE2 1 
ATOM   1848  N N   . ILE A 1 314 ? 122.332 102.686 109.527 1.00 62.98  ? 314 ILE A N   1 
ATOM   1849  C CA  . ILE A 1 314 ? 121.789 101.323 109.441 1.00 63.52  ? 314 ILE A CA  1 
ATOM   1850  C C   . ILE A 1 314 ? 120.374 101.282 110.023 1.00 57.93  ? 314 ILE A C   1 
ATOM   1851  O O   . ILE A 1 314 ? 119.447 100.790 109.390 1.00 68.08  ? 314 ILE A O   1 
ATOM   1852  C CB  . ILE A 1 314 ? 122.710 100.306 110.154 1.00 68.48  ? 314 ILE A CB  1 
ATOM   1853  C CG1 . ILE A 1 314 ? 124.099 100.202 109.492 1.00 61.78  ? 314 ILE A CG1 1 
ATOM   1854  C CG2 . ILE A 1 314 ? 122.063 98.909  110.163 1.00 63.16  ? 314 ILE A CG2 1 
ATOM   1855  C CD1 . ILE A 1 314 ? 125.151 99.562  110.402 1.00 58.04  ? 314 ILE A CD1 1 
ATOM   1856  N N   . LEU A 1 315 ? 120.200 101.842 111.217 1.00 54.75  ? 315 LEU A N   1 
ATOM   1857  C CA  . LEU A 1 315 ? 118.975 101.823 112.009 1.00 56.71  ? 315 LEU A CA  1 
ATOM   1858  C C   . LEU A 1 315 ? 117.771 102.461 111.292 1.00 60.42  ? 315 LEU A C   1 
ATOM   1859  O O   . LEU A 1 315 ? 116.653 101.968 111.405 1.00 58.37  ? 315 LEU A O   1 
ATOM   1860  C CB  . LEU A 1 315 ? 119.342 102.560 113.304 1.00 55.72  ? 315 LEU A CB  1 
ATOM   1861  C CG  . LEU A 1 315 ? 118.260 102.630 114.370 1.00 55.74  ? 315 LEU A CG  1 
ATOM   1862  C CD1 . LEU A 1 315 ? 118.163 101.293 115.095 1.00 60.48  ? 315 LEU A CD1 1 
ATOM   1863  C CD2 . LEU A 1 315 ? 118.621 103.734 115.353 1.00 53.29  ? 315 LEU A CD2 1 
ATOM   1864  N N   . GLN A 1 316 ? 117.994 103.538 110.545 1.00 66.47  ? 316 GLN A N   1 
ATOM   1865  C CA  . GLN A 1 316 ? 116.966 104.337 109.876 1.00 55.56  ? 316 GLN A CA  1 
ATOM   1866  C C   . GLN A 1 316 ? 116.926 104.149 108.350 1.00 56.46  ? 316 GLN A C   1 
ATOM   1867  O O   . GLN A 1 316 ? 116.262 104.909 107.654 1.00 64.01  ? 316 GLN A O   1 
ATOM   1868  C CB  . GLN A 1 316 ? 117.175 105.815 110.234 1.00 54.70  ? 316 GLN A CB  1 
ATOM   1869  C CG  . GLN A 1 316 ? 117.189 106.079 111.744 1.00 64.50  ? 316 GLN A CG  1 
ATOM   1870  C CD  . GLN A 1 316 ? 117.337 107.553 112.090 1.00 64.88  ? 316 GLN A CD  1 
ATOM   1871  O OE1 . GLN A 1 316 ? 117.688 108.393 111.278 1.00 68.29  ? 316 GLN A OE1 1 
ATOM   1872  N NE2 . GLN A 1 316 ? 117.067 107.924 113.316 1.00 66.15  ? 316 GLN A NE2 1 
ATOM   1873  N N   . ARG A 1 317 ? 117.647 103.170 107.805 1.00 62.04  ? 317 ARG A N   1 
ATOM   1874  C CA  . ARG A 1 317 ? 117.884 103.002 106.365 1.00 63.86  ? 317 ARG A CA  1 
ATOM   1875  C C   . ARG A 1 317 ? 116.608 102.768 105.566 1.00 72.51  ? 317 ARG A C   1 
ATOM   1876  O O   . ARG A 1 317 ? 115.839 101.871 105.896 1.00 77.90  ? 317 ARG A O   1 
ATOM   1877  C CB  . ARG A 1 317 ? 118.846 101.828 106.199 1.00 60.09  ? 317 ARG A CB  1 
ATOM   1878  C CG  . ARG A 1 317 ? 119.410 101.703 104.785 1.00 67.35  ? 317 ARG A CG  1 
ATOM   1879  C CD  . ARG A 1 317 ? 120.505 100.640 104.782 1.00 72.03  ? 317 ARG A CD  1 
ATOM   1880  N NE  . ARG A 1 317 ? 119.960 99.326  105.152 1.00 71.96  ? 317 ARG A NE  1 
ATOM   1881  C CZ  . ARG A 1 317 ? 120.480 98.436  105.962 1.00 66.89  ? 317 ARG A CZ  1 
ATOM   1882  N NH1 . ARG A 1 317 ? 119.825 97.354  106.213 1.00 60.17  ? 317 ARG A NH1 1 
ATOM   1883  N NH2 . ARG A 1 317 ? 121.650 98.582  106.489 1.00 70.51  ? 317 ARG A NH2 1 
ATOM   1884  N N   . GLU A 1 318 ? 116.418 103.497 104.473 1.00 76.44  ? 318 GLU A N   1 
ATOM   1885  C CA  . GLU A 1 318 ? 115.273 103.373 103.569 1.00 72.94  ? 318 GLU A CA  1 
ATOM   1886  C C   . GLU A 1 318 ? 115.730 103.380 102.106 1.00 81.31  ? 318 GLU A C   1 
ATOM   1887  O O   . GLU A 1 318 ? 116.537 104.225 101.719 1.00 77.91  ? 318 GLU A O   1 
ATOM   1888  C CB  . GLU A 1 318 ? 114.291 104.514 103.870 1.00 78.10  ? 318 GLU A CB  1 
ATOM   1889  C CG  . GLU A 1 318 ? 112.989 104.456 103.060 1.00 83.41  ? 318 GLU A CG  1 
ATOM   1890  C CD  . GLU A 1 318 ? 111.951 105.467 103.566 1.00 85.16  ? 318 GLU A CD  1 
ATOM   1891  O OE1 . GLU A 1 318 ? 112.341 106.569 104.006 1.00 87.02  ? 318 GLU A OE1 1 
ATOM   1892  O OE2 . GLU A 1 318 ? 110.729 105.192 103.486 1.00 84.73  ? 318 GLU A OE2 1 
ATOM   1893  N N   . PHE A 1 319 ? 115.193 102.479 101.283 1.00 92.69  ? 319 PHE A N   1 
ATOM   1894  C CA  . PHE A 1 319 ? 115.461 102.378 99.846  1.00 84.22  ? 319 PHE A CA  1 
ATOM   1895  C C   . PHE A 1 319 ? 114.160 102.223 99.045  1.00 89.26  ? 319 PHE A C   1 
ATOM   1896  O O   . PHE A 1 319 ? 113.137 101.787 99.571  1.00 89.18  ? 319 PHE A O   1 
ATOM   1897  C CB  . PHE A 1 319 ? 116.372 101.180 99.554  1.00 80.64  ? 319 PHE A CB  1 
ATOM   1898  C CG  . PHE A 1 319 ? 117.764 101.203 100.144 1.00 85.90  ? 319 PHE A CG  1 
ATOM   1899  C CD1 . PHE A 1 319 ? 118.669 102.231 99.823  1.00 90.44  ? 319 PHE A CD1 1 
ATOM   1900  C CD2 . PHE A 1 319 ? 118.186 100.141 100.947 1.00 84.74  ? 319 PHE A CD2 1 
ATOM   1901  C CE1 . PHE A 1 319 ? 119.988 102.185 100.310 1.00 88.60  ? 319 PHE A CE1 1 
ATOM   1902  C CE2 . PHE A 1 319 ? 119.507 100.083 101.416 1.00 84.03  ? 319 PHE A CE2 1 
ATOM   1903  C CZ  . PHE A 1 319 ? 120.409 101.106 101.100 1.00 86.64  ? 319 PHE A CZ  1 
ATOM   1904  N N   . SER A 1 320 ? 114.218 102.521 97.748  1.00 111.39 ? 320 SER A N   1 
ATOM   1905  C CA  . SER A 1 320 ? 113.121 102.356 96.788  1.00 112.20 ? 320 SER A CA  1 
ATOM   1906  C C   . SER A 1 320 ? 113.534 101.452 95.621  1.00 113.00 ? 320 SER A C   1 
ATOM   1907  O O   . SER A 1 320 ? 114.716 101.314 95.302  1.00 110.26 ? 320 SER A O   1 
ATOM   1908  C CB  . SER A 1 320 ? 112.638 103.722 96.294  1.00 108.90 ? 320 SER A CB  1 
ATOM   1909  O OG  . SER A 1 320 ? 113.671 104.406 95.610  1.00 110.02 ? 320 SER A OG  1 
ATOM   1910  N N   . GLY A 1 321 ? 112.566 100.790 94.990  1.00 107.71 ? 321 GLY A N   1 
ATOM   1911  C CA  . GLY A 1 321 ? 112.832 99.898  93.860  1.00 106.63 ? 321 GLY A CA  1 
ATOM   1912  C C   . GLY A 1 321 ? 113.427 98.548  94.289  1.00 108.95 ? 321 GLY A C   1 
ATOM   1913  O O   . GLY A 1 321 ? 112.945 97.975  95.270  1.00 110.26 ? 321 GLY A O   1 
ATOM   1914  N N   . PRO A 1 322 ? 114.444 98.003  93.589  1.00 109.84 ? 322 PRO A N   1 
ATOM   1915  C CA  . PRO A 1 322 ? 114.959 96.648  93.807  1.00 109.59 ? 322 PRO A CA  1 
ATOM   1916  C C   . PRO A 1 322 ? 115.405 96.344  95.243  1.00 107.78 ? 322 PRO A C   1 
ATOM   1917  O O   . PRO A 1 322 ? 115.271 95.216  95.711  1.00 106.29 ? 322 PRO A O   1 
ATOM   1918  C CB  . PRO A 1 322 ? 116.156 96.519  92.858  1.00 109.17 ? 322 PRO A CB  1 
ATOM   1919  C CG  . PRO A 1 322 ? 115.842 97.492  91.732  1.00 106.48 ? 322 PRO A CG  1 
ATOM   1920  C CD  . PRO A 1 322 ? 115.100 98.615  92.443  1.00 107.60 ? 322 PRO A CD  1 
ATOM   1921  N N   . TYR A 1 323 ? 115.893 97.371  95.937  1.00 93.97  ? 323 TYR A N   1 
ATOM   1922  C CA  . TYR A 1 323 ? 116.534 97.284  97.241  1.00 95.23  ? 323 TYR A CA  1 
ATOM   1923  C C   . TYR A 1 323 ? 115.612 97.562  98.432  1.00 93.23  ? 323 TYR A C   1 
ATOM   1924  O O   . TYR A 1 323 ? 116.091 97.619  99.559  1.00 97.11  ? 323 TYR A O   1 
ATOM   1925  C CB  . TYR A 1 323 ? 117.750 98.221  97.216  1.00 100.69 ? 323 TYR A CB  1 
ATOM   1926  C CG  . TYR A 1 323 ? 118.711 97.936  96.077  1.00 96.90  ? 323 TYR A CG  1 
ATOM   1927  C CD1 . TYR A 1 323 ? 119.145 96.619  95.821  1.00 96.31  ? 323 TYR A CD1 1 
ATOM   1928  C CD2 . TYR A 1 323 ? 119.147 98.986  95.250  1.00 94.79  ? 323 TYR A CD2 1 
ATOM   1929  C CE1 . TYR A 1 323 ? 119.981 96.345  94.724  1.00 94.85  ? 323 TYR A CE1 1 
ATOM   1930  C CE2 . TYR A 1 323 ? 119.991 98.717  94.157  1.00 98.54  ? 323 TYR A CE2 1 
ATOM   1931  C CZ  . TYR A 1 323 ? 120.399 97.397  93.887  1.00 98.17  ? 323 TYR A CZ  1 
ATOM   1932  O OH  . TYR A 1 323 ? 121.199 97.137  92.824  1.00 96.58  ? 323 TYR A OH  1 
ATOM   1933  N N   . GLN A 1 324 ? 114.297 97.701  98.246  1.00 92.57  ? 324 GLN A N   1 
ATOM   1934  C CA  . GLN A 1 324 ? 113.385 97.986  99.357  1.00 93.37  ? 324 GLN A CA  1 
ATOM   1935  C C   . GLN A 1 324 ? 113.513 97.012  100.558 1.00 93.55  ? 324 GLN A C   1 
ATOM   1936  O O   . GLN A 1 324 ? 113.566 97.513  101.678 1.00 92.85  ? 324 GLN A O   1 
ATOM   1937  C CB  . GLN A 1 324 ? 111.947 98.144  98.836  1.00 91.33  ? 324 GLN A CB  1 
ATOM   1938  C CG  . GLN A 1 324 ? 110.957 98.508  99.947  1.00 95.55  ? 324 GLN A CG  1 
ATOM   1939  C CD  . GLN A 1 324 ? 109.576 98.882  99.419  1.00 96.39  ? 324 GLN A CD  1 
ATOM   1940  O OE1 . GLN A 1 324 ? 109.101 98.377  98.421  1.00 95.87  ? 324 GLN A OE1 1 
ATOM   1941  N NE2 . GLN A 1 324 ? 108.871 99.774  100.058 1.00 94.68  ? 324 GLN A NE2 1 
ATOM   1942  N N   . PRO A 1 325 ? 113.654 95.679  100.401 1.00 88.38  ? 325 PRO A N   1 
ATOM   1943  C CA  . PRO A 1 325 ? 113.857 94.739  101.506 1.00 88.71  ? 325 PRO A CA  1 
ATOM   1944  C C   . PRO A 1 325 ? 115.130 94.953  102.337 1.00 86.62  ? 325 PRO A C   1 
ATOM   1945  O O   . PRO A 1 325 ? 115.214 94.462  103.456 1.00 89.31  ? 325 PRO A O   1 
ATOM   1946  C CB  . PRO A 1 325 ? 113.878 93.349  100.868 1.00 87.59  ? 325 PRO A CB  1 
ATOM   1947  C CG  . PRO A 1 325 ? 113.048 93.528  99.609  1.00 88.74  ? 325 PRO A CG  1 
ATOM   1948  C CD  . PRO A 1 325 ? 113.421 94.936  99.172  1.00 85.54  ? 325 PRO A CD  1 
ATOM   1949  N N   . LEU A 1 326 ? 116.111 95.690  101.809 1.00 82.88  ? 326 LEU A N   1 
ATOM   1950  C CA  . LEU A 1 326 ? 117.300 96.105  102.550 1.00 81.48  ? 326 LEU A CA  1 
ATOM   1951  C C   . LEU A 1 326 ? 117.016 97.300  103.473 1.00 83.38  ? 326 LEU A C   1 
ATOM   1952  O O   . LEU A 1 326 ? 117.881 97.687  104.250 1.00 83.24  ? 326 LEU A O   1 
ATOM   1953  C CB  . LEU A 1 326 ? 118.457 96.411  101.581 1.00 80.38  ? 326 LEU A CB  1 
ATOM   1954  C CG  . LEU A 1 326 ? 118.819 95.292  100.596 1.00 78.88  ? 326 LEU A CG  1 
ATOM   1955  C CD1 . LEU A 1 326 ? 119.930 95.785  99.685  1.00 82.14  ? 326 LEU A CD1 1 
ATOM   1956  C CD2 . LEU A 1 326 ? 119.288 94.030  101.304 1.00 79.38  ? 326 LEU A CD2 1 
ATOM   1957  N N   . SER A 1 327 ? 115.830 97.905  103.422 1.00 79.70  ? 327 SER A N   1 
ATOM   1958  C CA  . SER A 1 327 ? 115.419 98.955  104.357 1.00 76.74  ? 327 SER A CA  1 
ATOM   1959  C C   . SER A 1 327 ? 115.213 98.403  105.766 1.00 75.60  ? 327 SER A C   1 
ATOM   1960  O O   . SER A 1 327 ? 114.785 97.263  105.947 1.00 71.05  ? 327 SER A O   1 
ATOM   1961  C CB  . SER A 1 327 ? 114.113 99.616  103.926 1.00 70.26  ? 327 SER A CB  1 
ATOM   1962  O OG  . SER A 1 327 ? 114.155 100.009 102.578 1.00 69.84  ? 327 SER A OG  1 
ATOM   1963  N N   . ARG A 1 328 ? 115.453 99.247  106.770 1.00 70.08  ? 328 ARG A N   1 
ATOM   1964  C CA  . ARG A 1 328 ? 114.924 99.091  108.128 1.00 63.43  ? 328 ARG A CA  1 
ATOM   1965  C C   . ARG A 1 328 ? 113.770 100.048 108.421 1.00 69.77  ? 328 ARG A C   1 
ATOM   1966  O O   . ARG A 1 328 ? 113.003 99.783  109.329 1.00 84.99  ? 328 ARG A O   1 
ATOM   1967  C CB  . ARG A 1 328 ? 116.039 99.274  109.162 1.00 63.15  ? 328 ARG A CB  1 
ATOM   1968  C CG  . ARG A 1 328 ? 117.084 98.158  109.125 1.00 63.99  ? 328 ARG A CG  1 
ATOM   1969  C CD  . ARG A 1 328 ? 117.933 98.157  110.400 1.00 71.03  ? 328 ARG A CD  1 
ATOM   1970  N NE  . ARG A 1 328 ? 117.194 97.618  111.554 1.00 68.65  ? 328 ARG A NE  1 
ATOM   1971  C CZ  . ARG A 1 328 ? 117.229 96.385  112.003 1.00 70.82  ? 328 ARG A CZ  1 
ATOM   1972  N NH1 . ARG A 1 328 ? 116.433 96.027  112.957 1.00 72.88  ? 328 ARG A NH1 1 
ATOM   1973  N NH2 . ARG A 1 328 ? 118.022 95.486  111.510 1.00 70.40  ? 328 ARG A NH2 1 
ATOM   1974  N N   . LYS A 1 329 ? 113.625 101.139 107.671 1.00 59.74  ? 329 LYS A N   1 
ATOM   1975  C CA  . LYS A 1 329 ? 112.542 102.126 107.760 1.00 54.97  ? 329 LYS A CA  1 
ATOM   1976  C C   . LYS A 1 329 ? 111.683 102.072 106.506 1.00 61.48  ? 329 LYS A C   1 
ATOM   1977  O O   . LYS A 1 329 ? 112.213 102.141 105.405 1.00 75.22  ? 329 LYS A O   1 
ATOM   1978  C CB  . LYS A 1 329 ? 113.178 103.506 107.926 1.00 59.57  ? 329 LYS A CB  1 
ATOM   1979  C CG  . LYS A 1 329 ? 112.196 104.680 107.962 1.00 57.47  ? 329 LYS A CG  1 
ATOM   1980  C CD  . LYS A 1 329 ? 112.984 105.989 107.898 1.00 59.91  ? 329 LYS A CD  1 
ATOM   1981  C CE  . LYS A 1 329 ? 112.055 107.193 107.992 1.00 66.45  ? 329 LYS A CE  1 
ATOM   1982  N NZ  . LYS A 1 329 ? 112.797 108.463 107.815 1.00 64.85  ? 329 LYS A NZ  1 
ATOM   1983  N N   . PHE A 1 330 ? 110.368 102.011 106.657 1.00 65.44  ? 330 PHE A N   1 
ATOM   1984  C CA  . PHE A 1 330 ? 109.411 102.058 105.554 1.00 66.30  ? 330 PHE A CA  1 
ATOM   1985  C C   . PHE A 1 330 ? 108.436 103.215 105.766 1.00 71.80  ? 330 PHE A C   1 
ATOM   1986  O O   . PHE A 1 330 ? 107.657 103.172 106.712 1.00 76.23  ? 330 PHE A O   1 
ATOM   1987  C CB  . PHE A 1 330 ? 108.670 100.715 105.474 1.00 63.24  ? 330 PHE A CB  1 
ATOM   1988  C CG  . PHE A 1 330 ? 109.576 99.506  105.416 1.00 69.94  ? 330 PHE A CG  1 
ATOM   1989  C CD1 . PHE A 1 330 ? 110.032 98.909  106.606 1.00 71.60  ? 330 PHE A CD1 1 
ATOM   1990  C CD2 . PHE A 1 330 ? 109.986 98.985  104.176 1.00 68.42  ? 330 PHE A CD2 1 
ATOM   1991  C CE1 . PHE A 1 330 ? 110.907 97.819  106.559 1.00 70.83  ? 330 PHE A CE1 1 
ATOM   1992  C CE2 . PHE A 1 330 ? 110.842 97.877  104.127 1.00 69.24  ? 330 PHE A CE2 1 
ATOM   1993  C CZ  . PHE A 1 330 ? 111.309 97.303  105.318 1.00 75.42  ? 330 PHE A CZ  1 
ATOM   1994  N N   . THR A 1 331 ? 108.434 104.239 104.917 1.00 77.85  ? 331 THR A N   1 
ATOM   1995  C CA  . THR A 1 331 ? 107.417 105.300 104.990 1.00 73.69  ? 331 THR A CA  1 
ATOM   1996  C C   . THR A 1 331 ? 106.043 104.728 104.649 1.00 70.69  ? 331 THR A C   1 
ATOM   1997  O O   . THR A 1 331 ? 105.837 104.209 103.556 1.00 75.83  ? 331 THR A O   1 
ATOM   1998  C CB  . THR A 1 331 ? 107.738 106.477 104.064 1.00 78.69  ? 331 THR A CB  1 
ATOM   1999  O OG1 . THR A 1 331 ? 108.995 107.029 104.375 1.00 80.96  ? 331 THR A OG1 1 
ATOM   2000  C CG2 . THR A 1 331 ? 106.727 107.609 104.221 1.00 75.64  ? 331 THR A CG2 1 
ATOM   2001  N N   . GLU A 1 332 ? 105.089 104.812 105.572 1.00 73.33  ? 332 GLU A N   1 
ATOM   2002  C CA  . GLU A 1 332 ? 103.719 104.337 105.396 1.00 75.72  ? 332 GLU A CA  1 
ATOM   2003  C C   . GLU A 1 332 ? 102.869 105.360 104.637 1.00 80.85  ? 332 GLU A C   1 
ATOM   2004  O O   . GLU A 1 332 ? 102.228 105.030 103.639 1.00 79.33  ? 332 GLU A O   1 
ATOM   2005  C CB  . GLU A 1 332 ? 103.114 104.023 106.771 1.00 72.89  ? 332 GLU A CB  1 
ATOM   2006  C CG  . GLU A 1 332 ? 101.692 103.477 106.632 1.00 80.28  ? 332 GLU A CG  1 
ATOM   2007  C CD  . GLU A 1 332 ? 101.026 103.183 107.974 1.00 88.18  ? 332 GLU A CD  1 
ATOM   2008  O OE1 . GLU A 1 332 ? 101.697 102.682 108.899 1.00 89.63  ? 332 GLU A OE1 1 
ATOM   2009  O OE2 . GLU A 1 332 ? 99.805  103.413 108.101 1.00 86.34  ? 332 GLU A OE2 1 
ATOM   2010  N N   . TRP A 1 333 ? 102.883 106.612 105.095 1.00 75.72  ? 333 TRP A N   1 
ATOM   2011  C CA  . TRP A 1 333 ? 102.314 107.757 104.390 1.00 69.12  ? 333 TRP A CA  1 
ATOM   2012  C C   . TRP A 1 333 ? 103.035 109.045 104.771 1.00 69.11  ? 333 TRP A C   1 
ATOM   2013  O O   . TRP A 1 333 ? 103.681 109.146 105.809 1.00 76.17  ? 333 TRP A O   1 
ATOM   2014  C CB  . TRP A 1 333 ? 100.794 107.852 104.598 1.00 68.11  ? 333 TRP A CB  1 
ATOM   2015  C CG  . TRP A 1 333 ? 100.260 108.041 105.986 1.00 68.38  ? 333 TRP A CG  1 
ATOM   2016  C CD1 . TRP A 1 333 ? 99.707  107.065 106.735 1.00 68.47  ? 333 TRP A CD1 1 
ATOM   2017  C CD2 . TRP A 1 333 ? 100.143 109.261 106.784 1.00 74.00  ? 333 TRP A CD2 1 
ATOM   2018  N NE1 . TRP A 1 333 ? 99.260  107.588 107.927 1.00 69.03  ? 333 TRP A NE1 1 
ATOM   2019  C CE2 . TRP A 1 333 ? 99.485  108.941 108.003 1.00 69.90  ? 333 TRP A CE2 1 
ATOM   2020  C CE3 . TRP A 1 333 ? 100.497 110.614 106.601 1.00 77.88  ? 333 TRP A CE3 1 
ATOM   2021  C CZ2 . TRP A 1 333 ? 99.200  109.901 108.979 1.00 66.92  ? 333 TRP A CZ2 1 
ATOM   2022  C CZ3 . TRP A 1 333 ? 100.239 111.581 107.588 1.00 69.62  ? 333 TRP A CZ3 1 
ATOM   2023  C CH2 . TRP A 1 333 ? 99.583  111.231 108.772 1.00 68.74  ? 333 TRP A CH2 1 
ATOM   2024  N N   . CYS A 1 334 ? 102.925 110.045 103.912 1.00 77.58  ? 334 CYS A N   1 
ATOM   2025  C CA  . CYS A 1 334 ? 103.438 111.388 104.124 1.00 77.52  ? 334 CYS A CA  1 
ATOM   2026  C C   . CYS A 1 334 ? 102.384 112.404 103.674 1.00 82.08  ? 334 CYS A C   1 
ATOM   2027  O O   . CYS A 1 334 ? 101.792 112.254 102.600 1.00 86.72  ? 334 CYS A O   1 
ATOM   2028  C CB  . CYS A 1 334 ? 104.759 111.517 103.364 1.00 82.34  ? 334 CYS A CB  1 
ATOM   2029  S SG  . CYS A 1 334 ? 105.432 113.184 103.538 1.00 93.31  ? 334 CYS A SG  1 
ATOM   2030  N N   . TYR A 1 335 ? 102.129 113.421 104.491 1.00 73.79  ? 335 TYR A N   1 
ATOM   2031  C CA  . TYR A 1 335 ? 101.129 114.450 104.223 1.00 75.48  ? 335 TYR A CA  1 
ATOM   2032  C C   . TYR A 1 335 ? 101.534 115.764 104.885 1.00 74.68  ? 335 TYR A C   1 
ATOM   2033  O O   . TYR A 1 335 ? 101.549 115.883 106.109 1.00 77.59  ? 335 TYR A O   1 
ATOM   2034  C CB  . TYR A 1 335 ? 99.749  113.973 104.685 1.00 76.01  ? 335 TYR A CB  1 
ATOM   2035  C CG  . TYR A 1 335 ? 98.613  114.871 104.255 1.00 77.75  ? 335 TYR A CG  1 
ATOM   2036  C CD1 . TYR A 1 335 ? 98.024  114.705 102.989 1.00 78.66  ? 335 TYR A CD1 1 
ATOM   2037  C CD2 . TYR A 1 335 ? 98.156  115.886 105.106 1.00 72.59  ? 335 TYR A CD2 1 
ATOM   2038  C CE1 . TYR A 1 335 ? 97.007  115.573 102.568 1.00 76.74  ? 335 TYR A CE1 1 
ATOM   2039  C CE2 . TYR A 1 335 ? 97.129  116.750 104.691 1.00 72.75  ? 335 TYR A CE2 1 
ATOM   2040  C CZ  . TYR A 1 335 ? 96.567  116.609 103.412 1.00 77.48  ? 335 TYR A CZ  1 
ATOM   2041  O OH  . TYR A 1 335 ? 95.618  117.482 102.998 1.00 79.17  ? 335 TYR A OH  1 
ATOM   2042  N N   . GLY A 1 336 ? 101.897 116.757 104.086 1.00 73.00  ? 336 GLY A N   1 
ATOM   2043  C CA  . GLY A 1 336 ? 102.410 118.019 104.581 1.00 74.84  ? 336 GLY A CA  1 
ATOM   2044  C C   . GLY A 1 336 ? 103.691 117.793 105.388 1.00 77.83  ? 336 GLY A C   1 
ATOM   2045  O O   . GLY A 1 336 ? 104.539 117.014 104.957 1.00 79.79  ? 336 GLY A O   1 
ATOM   2046  N N   . PRO A 1 337 ? 103.857 118.421 106.560 1.00 77.11  ? 337 PRO A N   1 
ATOM   2047  C CA  . PRO A 1 337 ? 105.039 118.275 107.395 1.00 77.58  ? 337 PRO A CA  1 
ATOM   2048  C C   . PRO A 1 337 ? 105.108 116.924 108.119 1.00 81.45  ? 337 PRO A C   1 
ATOM   2049  O O   . PRO A 1 337 ? 106.059 116.696 108.864 1.00 80.76  ? 337 PRO A O   1 
ATOM   2050  C CB  . PRO A 1 337 ? 104.959 119.447 108.371 1.00 69.71  ? 337 PRO A CB  1 
ATOM   2051  C CG  . PRO A 1 337 ? 103.465 119.616 108.564 1.00 73.21  ? 337 PRO A CG  1 
ATOM   2052  C CD  . PRO A 1 337 ? 102.916 119.320 107.180 1.00 72.39  ? 337 PRO A CD  1 
ATOM   2053  N N   . VAL A 1 338 ? 104.121 116.042 107.945 1.00 83.39  ? 338 VAL A N   1 
ATOM   2054  C CA  . VAL A 1 338 ? 103.968 114.808 108.718 1.00 80.52  ? 338 VAL A CA  1 
ATOM   2055  C C   . VAL A 1 338 ? 104.395 113.600 107.900 1.00 80.90  ? 338 VAL A C   1 
ATOM   2056  O O   . VAL A 1 338 ? 103.845 113.347 106.831 1.00 82.96  ? 338 VAL A O   1 
ATOM   2057  C CB  . VAL A 1 338 ? 102.522 114.622 109.208 1.00 74.15  ? 338 VAL A CB  1 
ATOM   2058  C CG1 . VAL A 1 338 ? 102.452 113.485 110.230 1.00 74.68  ? 338 VAL A CG1 1 
ATOM   2059  C CG2 . VAL A 1 338 ? 101.974 115.911 109.822 1.00 71.64  ? 338 VAL A CG2 1 
ATOM   2060  N N   . ARG A 1 339 ? 105.338 112.814 108.424 1.00 81.97  ? 339 ARG A N   1 
ATOM   2061  C CA  . ARG A 1 339 ? 105.703 111.493 107.907 1.00 82.30  ? 339 ARG A CA  1 
ATOM   2062  C C   . ARG A 1 339 ? 105.331 110.429 108.921 1.00 81.74  ? 339 ARG A C   1 
ATOM   2063  O O   . ARG A 1 339 ? 105.695 110.550 110.083 1.00 90.00  ? 339 ARG A O   1 
ATOM   2064  C CB  . ARG A 1 339 ? 107.205 111.408 107.620 1.00 84.63  ? 339 ARG A CB  1 
ATOM   2065  C CG  . ARG A 1 339 ? 107.682 112.436 106.590 1.00 88.26  ? 339 ARG A CG  1 
ATOM   2066  C CD  . ARG A 1 339 ? 109.124 112.165 106.157 1.00 86.21  ? 339 ARG A CD  1 
ATOM   2067  N NE  . ARG A 1 339 ? 109.221 110.960 105.307 1.00 90.05  ? 339 ARG A NE  1 
ATOM   2068  C CZ  . ARG A 1 339 ? 109.298 110.921 103.989 1.00 93.03  ? 339 ARG A CZ  1 
ATOM   2069  N NH1 . ARG A 1 339 ? 109.378 109.783 103.366 1.00 91.10  ? 339 ARG A NH1 1 
ATOM   2070  N NH2 . ARG A 1 339 ? 109.298 111.995 103.256 1.00 93.48  ? 339 ARG A NH2 1 
ATOM   2071  N N   . VAL A 1 340 ? 104.678 109.359 108.493 1.00 68.47  ? 340 VAL A N   1 
ATOM   2072  C CA  . VAL A 1 340 ? 104.478 108.159 109.310 1.00 66.56  ? 340 VAL A CA  1 
ATOM   2073  C C   . VAL A 1 340 ? 105.333 107.034 108.751 1.00 75.70  ? 340 VAL A C   1 
ATOM   2074  O O   . VAL A 1 340 ? 105.247 106.726 107.568 1.00 85.22  ? 340 VAL A O   1 
ATOM   2075  C CB  . VAL A 1 340 ? 102.995 107.794 109.393 1.00 64.03  ? 340 VAL A CB  1 
ATOM   2076  C CG1 . VAL A 1 340 ? 102.780 106.535 110.229 1.00 70.34  ? 340 VAL A CG1 1 
ATOM   2077  C CG2 . VAL A 1 340 ? 102.244 108.953 110.045 1.00 73.70  ? 340 VAL A CG2 1 
ATOM   2078  N N   . SER A 1 341 ? 106.177 106.423 109.580 1.00 70.89  ? 341 SER A N   1 
ATOM   2079  C CA  . SER A 1 341 ? 107.136 105.396 109.170 1.00 65.48  ? 341 SER A CA  1 
ATOM   2080  C C   . SER A 1 341 ? 107.065 104.178 110.071 1.00 67.10  ? 341 SER A C   1 
ATOM   2081  O O   . SER A 1 341 ? 107.008 104.309 111.286 1.00 82.65  ? 341 SER A O   1 
ATOM   2082  C CB  . SER A 1 341 ? 108.566 105.925 109.206 1.00 68.13  ? 341 SER A CB  1 
ATOM   2083  O OG  . SER A 1 341 ? 108.717 107.079 108.411 1.00 78.86  ? 341 SER A OG  1 
ATOM   2084  N N   . LEU A 1 342 ? 107.136 102.989 109.491 1.00 61.67  ? 342 LEU A N   1 
ATOM   2085  C CA  . LEU A 1 342 ? 107.376 101.739 110.198 1.00 58.61  ? 342 LEU A CA  1 
ATOM   2086  C C   . LEU A 1 342 ? 108.880 101.501 110.306 1.00 59.97  ? 342 LEU A C   1 
ATOM   2087  O O   . LEU A 1 342 ? 109.562 101.473 109.292 1.00 71.36  ? 342 LEU A O   1 
ATOM   2088  C CB  . LEU A 1 342 ? 106.727 100.599 109.403 1.00 64.04  ? 342 LEU A CB  1 
ATOM   2089  C CG  . LEU A 1 342 ? 105.202 100.657 109.297 1.00 60.17  ? 342 LEU A CG  1 
ATOM   2090  C CD1 . LEU A 1 342 ? 104.722 99.488  108.448 1.00 68.02  ? 342 LEU A CD1 1 
ATOM   2091  C CD2 . LEU A 1 342 ? 104.532 100.569 110.661 1.00 60.14  ? 342 LEU A CD2 1 
ATOM   2092  N N   . TYR A 1 343 ? 109.407 101.309 111.507 1.00 57.47  ? 343 TYR A N   1 
ATOM   2093  C CA  . TYR A 1 343 ? 110.798 100.938 111.749 1.00 58.15  ? 343 TYR A CA  1 
ATOM   2094  C C   . TYR A 1 343 ? 110.904 99.480  112.199 1.00 67.60  ? 343 TYR A C   1 
ATOM   2095  O O   . TYR A 1 343 ? 110.166 99.040  113.069 1.00 75.03  ? 343 TYR A O   1 
ATOM   2096  C CB  . TYR A 1 343 ? 111.397 101.863 112.797 1.00 56.61  ? 343 TYR A CB  1 
ATOM   2097  C CG  . TYR A 1 343 ? 111.694 103.272 112.332 1.00 52.20  ? 343 TYR A CG  1 
ATOM   2098  C CD1 . TYR A 1 343 ? 110.713 104.272 112.421 1.00 55.58  ? 343 TYR A CD1 1 
ATOM   2099  C CD2 . TYR A 1 343 ? 112.985 103.597 111.893 1.00 56.32  ? 343 TYR A CD2 1 
ATOM   2100  C CE1 . TYR A 1 343 ? 111.042 105.603 112.107 1.00 61.52  ? 343 TYR A CE1 1 
ATOM   2101  C CE2 . TYR A 1 343 ? 113.317 104.929 111.604 1.00 59.31  ? 343 TYR A CE2 1 
ATOM   2102  C CZ  . TYR A 1 343 ? 112.350 105.940 111.736 1.00 61.95  ? 343 TYR A CZ  1 
ATOM   2103  O OH  . TYR A 1 343 ? 112.666 107.237 111.500 1.00 62.91  ? 343 TYR A OH  1 
ATOM   2104  N N   . ASP A 1 344 ? 111.824 98.721  111.623 1.00 71.01  ? 344 ASP A N   1 
ATOM   2105  C CA  . ASP A 1 344 ? 112.094 97.315  111.912 1.00 69.50  ? 344 ASP A CA  1 
ATOM   2106  C C   . ASP A 1 344 ? 112.877 97.128  113.227 1.00 72.06  ? 344 ASP A C   1 
ATOM   2107  O O   . ASP A 1 344 ? 114.016 97.583  113.346 1.00 78.52  ? 344 ASP A O   1 
ATOM   2108  C CB  . ASP A 1 344 ? 112.868 96.781  110.705 1.00 72.25  ? 344 ASP A CB  1 
ATOM   2109  C CG  . ASP A 1 344 ? 113.274 95.317  110.790 1.00 71.87  ? 344 ASP A CG  1 
ATOM   2110  O OD1 . ASP A 1 344 ? 112.897 94.637  111.766 1.00 76.52  ? 344 ASP A OD1 1 
ATOM   2111  O OD2 . ASP A 1 344 ? 113.948 94.862  109.843 1.00 63.91  ? 344 ASP A OD2 1 
ATOM   2112  N N   . LEU A 1 345 ? 112.289 96.446  114.216 1.00 66.69  ? 345 LEU A N   1 
ATOM   2113  C CA  . LEU A 1 345 ? 112.856 96.282  115.555 1.00 60.02  ? 345 LEU A CA  1 
ATOM   2114  C C   . LEU A 1 345 ? 113.650 94.982  115.782 1.00 60.34  ? 345 LEU A C   1 
ATOM   2115  O O   . LEU A 1 345 ? 113.961 94.671  116.929 1.00 70.84  ? 345 LEU A O   1 
ATOM   2116  C CB  . LEU A 1 345 ? 111.754 96.435  116.616 1.00 61.42  ? 345 LEU A CB  1 
ATOM   2117  C CG  . LEU A 1 345 ? 111.038 97.786  116.691 1.00 57.89  ? 345 LEU A CG  1 
ATOM   2118  C CD1 . LEU A 1 345 ? 110.278 97.830  118.011 1.00 68.00  ? 345 LEU A CD1 1 
ATOM   2119  C CD2 . LEU A 1 345 ? 111.994 98.972  116.667 1.00 65.68  ? 345 LEU A CD2 1 
ATOM   2120  N N   . SER A 1 346 ? 114.003 94.222  114.743 1.00 65.68  ? 346 SER A N   1 
ATOM   2121  C CA  . SER A 1 346 ? 114.529 92.847  114.858 1.00 73.41  ? 346 SER A CA  1 
ATOM   2122  C C   . SER A 1 346 ? 115.641 92.635  115.903 1.00 79.54  ? 346 SER A C   1 
ATOM   2123  O O   . SER A 1 346 ? 115.452 91.876  116.852 1.00 84.43  ? 346 SER A O   1 
ATOM   2124  C CB  . SER A 1 346 ? 114.975 92.335  113.487 1.00 73.10  ? 346 SER A CB  1 
ATOM   2125  O OG  . SER A 1 346 ? 116.032 93.111  112.942 1.00 71.95  ? 346 SER A OG  1 
ATOM   2126  N N   . SER A 1 347 ? 116.778 93.321  115.780 1.00 67.78  ? 347 SER A N   1 
ATOM   2127  C CA  . SER A 1 347 ? 117.879 93.315  116.748 1.00 60.97  ? 347 SER A CA  1 
ATOM   2128  C C   . SER A 1 347 ? 117.715 94.312  117.898 1.00 67.38  ? 347 SER A C   1 
ATOM   2129  O O   . SER A 1 347 ? 118.616 94.424  118.726 1.00 77.64  ? 347 SER A O   1 
ATOM   2130  C CB  . SER A 1 347 ? 119.189 93.645  116.023 1.00 67.47  ? 347 SER A CB  1 
ATOM   2131  O OG  . SER A 1 347 ? 119.383 92.839  114.877 1.00 70.30  ? 347 SER A OG  1 
ATOM   2132  N N   . VAL A 1 348 ? 116.644 95.108  117.916 1.00 67.71  ? 348 VAL A N   1 
ATOM   2133  C CA  . VAL A 1 348 ? 116.544 96.358  118.684 1.00 61.35  ? 348 VAL A CA  1 
ATOM   2134  C C   . VAL A 1 348 ? 115.740 96.232  119.974 1.00 59.48  ? 348 VAL A C   1 
ATOM   2135  O O   . VAL A 1 348 ? 116.172 96.751  120.996 1.00 63.30  ? 348 VAL A O   1 
ATOM   2136  C CB  . VAL A 1 348 ? 116.019 97.504  117.801 1.00 61.56  ? 348 VAL A CB  1 
ATOM   2137  C CG1 . VAL A 1 348 ? 115.901 98.828  118.551 1.00 59.46  ? 348 VAL A CG1 1 
ATOM   2138  C CG2 . VAL A 1 348 ? 116.934 97.763  116.601 1.00 61.42  ? 348 VAL A CG2 1 
ATOM   2139  N N   . ASP A 1 349 ? 114.583 95.579  119.916 1.00 74.71  ? 349 ASP A N   1 
ATOM   2140  C CA  . ASP A 1 349 ? 113.697 95.456  121.066 1.00 77.73  ? 349 ASP A CA  1 
ATOM   2141  C C   . ASP A 1 349 ? 114.325 94.558  122.141 1.00 88.05  ? 349 ASP A C   1 
ATOM   2142  O O   . ASP A 1 349 ? 114.832 93.472  121.863 1.00 88.56  ? 349 ASP A O   1 
ATOM   2143  C CB  . ASP A 1 349 ? 112.321 94.951  120.614 1.00 73.42  ? 349 ASP A CB  1 
ATOM   2144  C CG  . ASP A 1 349 ? 111.278 94.917  121.740 1.00 86.49  ? 349 ASP A CG  1 
ATOM   2145  O OD1 . ASP A 1 349 ? 111.486 95.593  122.777 1.00 86.69  ? 349 ASP A OD1 1 
ATOM   2146  O OD2 . ASP A 1 349 ? 110.271 94.200  121.568 1.00 90.94  ? 349 ASP A OD2 1 
ATOM   2147  N N   . SER A 1 350 ? 114.248 95.000  123.391 1.00 85.64  ? 350 SER A N   1 
ATOM   2148  C CA  . SER A 1 350 ? 114.809 94.368  124.582 1.00 78.85  ? 350 SER A CA  1 
ATOM   2149  C C   . SER A 1 350 ? 114.157 93.038  124.970 1.00 74.93  ? 350 SER A C   1 
ATOM   2150  O O   . SER A 1 350 ? 114.619 92.370  125.896 1.00 78.80  ? 350 SER A O   1 
ATOM   2151  C CB  . SER A 1 350 ? 114.730 95.379  125.717 1.00 82.47  ? 350 SER A CB  1 
ATOM   2152  O OG  . SER A 1 350 ? 113.417 95.869  125.829 1.00 86.56  ? 350 SER A OG  1 
ATOM   2153  N N   . TRP A 1 351 ? 113.116 92.621  124.255 1.00 82.44  ? 351 TRP A N   1 
ATOM   2154  C CA  . TRP A 1 351 ? 112.575 91.265  124.266 1.00 85.36  ? 351 TRP A CA  1 
ATOM   2155  C C   . TRP A 1 351 ? 113.625 90.213  123.874 1.00 89.91  ? 351 TRP A C   1 
ATOM   2156  O O   . TRP A 1 351 ? 113.661 89.127  124.447 1.00 91.59  ? 351 TRP A O   1 
ATOM   2157  C CB  . TRP A 1 351 ? 111.375 91.257  123.312 1.00 84.69  ? 351 TRP A CB  1 
ATOM   2158  C CG  . TRP A 1 351 ? 110.718 89.940  123.071 1.00 89.69  ? 351 TRP A CG  1 
ATOM   2159  C CD1 . TRP A 1 351 ? 109.676 89.448  123.775 1.00 91.81  ? 351 TRP A CD1 1 
ATOM   2160  C CD2 . TRP A 1 351 ? 111.038 88.931  122.068 1.00 93.15  ? 351 TRP A CD2 1 
ATOM   2161  N NE1 . TRP A 1 351 ? 109.332 88.207  123.286 1.00 89.85  ? 351 TRP A NE1 1 
ATOM   2162  C CE2 . TRP A 1 351 ? 110.137 87.836  122.231 1.00 90.81  ? 351 TRP A CE2 1 
ATOM   2163  C CE3 . TRP A 1 351 ? 111.983 88.830  121.026 1.00 92.06  ? 351 TRP A CE3 1 
ATOM   2164  C CZ2 . TRP A 1 351 ? 110.183 86.698  121.418 1.00 86.56  ? 351 TRP A CZ2 1 
ATOM   2165  C CZ3 . TRP A 1 351 ? 112.043 87.686  120.207 1.00 90.74  ? 351 TRP A CZ3 1 
ATOM   2166  C CH2 . TRP A 1 351 ? 111.149 86.622  120.403 1.00 87.77  ? 351 TRP A CH2 1 
ATOM   2167  N N   . GLU A 1 352 ? 114.523 90.543  122.944 1.00 95.32  ? 352 GLU A N   1 
ATOM   2168  C CA  . GLU A 1 352 ? 115.681 89.717  122.588 1.00 95.96  ? 352 GLU A CA  1 
ATOM   2169  C C   . GLU A 1 352 ? 116.848 89.912  123.576 1.00 97.84  ? 352 GLU A C   1 
ATOM   2170  O O   . GLU A 1 352 ? 117.221 91.042  123.911 1.00 99.88  ? 352 GLU A O   1 
ATOM   2171  C CB  . GLU A 1 352 ? 116.081 90.014  121.129 1.00 91.70  ? 352 GLU A CB  1 
ATOM   2172  N N   . LYS A 1 353 ? 117.476 88.813  124.007 1.00 89.28  ? 353 LYS A N   1 
ATOM   2173  C CA  . LYS A 1 353 ? 118.716 88.830  124.800 1.00 89.62  ? 353 LYS A CA  1 
ATOM   2174  C C   . LYS A 1 353 ? 119.886 89.337  123.960 1.00 93.23  ? 353 LYS A C   1 
ATOM   2175  O O   . LYS A 1 353 ? 120.003 88.952  122.799 1.00 91.67  ? 353 LYS A O   1 
ATOM   2176  C CB  . LYS A 1 353 ? 119.014 87.420  125.336 1.00 91.53  ? 353 LYS A CB  1 
ATOM   2177  C CG  . LYS A 1 353 ? 117.944 86.908  126.309 1.00 94.52  ? 353 LYS A CG  1 
ATOM   2178  C CD  . LYS A 1 353 ? 118.274 85.490  126.783 1.00 95.05  ? 353 LYS A CD  1 
ATOM   2179  C CE  . LYS A 1 353 ? 117.175 84.975  127.712 1.00 93.52  ? 353 LYS A CE  1 
ATOM   2180  N NZ  . LYS A 1 353 ? 117.435 83.587  128.153 1.00 95.07  ? 353 LYS A NZ  1 
ATOM   2181  N N   . ASN A 1 354 ? 120.776 90.157  124.523 1.00 81.99  ? 354 ASN A N   1 
ATOM   2182  C CA  . ASN A 1 354 ? 121.874 90.795  123.781 1.00 78.89  ? 354 ASN A CA  1 
ATOM   2183  C C   . ASN A 1 354 ? 121.377 91.652  122.599 1.00 79.07  ? 354 ASN A C   1 
ATOM   2184  O O   . ASN A 1 354 ? 121.877 91.564  121.480 1.00 85.90  ? 354 ASN A O   1 
ATOM   2185  C CB  . ASN A 1 354 ? 122.938 89.740  123.420 1.00 86.04  ? 354 ASN A CB  1 
ATOM   2186  C CG  . ASN A 1 354 ? 124.227 90.344  122.900 1.00 90.81  ? 354 ASN A CG  1 
ATOM   2187  O OD1 . ASN A 1 354 ? 124.691 91.366  123.377 1.00 88.85  ? 354 ASN A OD1 1 
ATOM   2188  N ND2 . ASN A 1 354 ? 124.857 89.722  121.935 1.00 84.37  ? 354 ASN A ND2 1 
ATOM   2189  N N   . SER A 1 355 ? 120.315 92.428  122.801 1.00 69.85  ? 355 SER A N   1 
ATOM   2190  C CA  . SER A 1 355 ? 119.766 93.387  121.836 1.00 59.36  ? 355 SER A CA  1 
ATOM   2191  C C   . SER A 1 355 ? 120.478 94.740  121.889 1.00 62.73  ? 355 SER A C   1 
ATOM   2192  O O   . SER A 1 355 ? 121.219 95.038  122.817 1.00 78.13  ? 355 SER A O   1 
ATOM   2193  C CB  . SER A 1 355 ? 118.270 93.564  122.088 1.00 59.88  ? 355 SER A CB  1 
ATOM   2194  O OG  . SER A 1 355 ? 118.012 93.710  123.465 1.00 60.43  ? 355 SER A OG  1 
ATOM   2195  N N   . VAL A 1 356 ? 120.249 95.586  120.890 1.00 46.41  ? 356 VAL A N   1 
ATOM   2196  C CA  . VAL A 1 356 ? 120.870 96.919  120.747 1.00 39.39  ? 356 VAL A CA  1 
ATOM   2197  C C   . VAL A 1 356 ? 120.616 97.827  121.950 1.00 46.49  ? 356 VAL A C   1 
ATOM   2198  O O   . VAL A 1 356 ? 121.496 98.584  122.334 1.00 70.73  ? 356 VAL A O   1 
ATOM   2199  C CB  . VAL A 1 356 ? 120.386 97.589  119.451 1.00 49.47  ? 356 VAL A CB  1 
ATOM   2200  C CG1 . VAL A 1 356 ? 120.673 99.078  119.320 1.00 52.94  ? 356 VAL A CG1 1 
ATOM   2201  C CG2 . VAL A 1 356 ? 120.999 96.904  118.231 1.00 52.81  ? 356 VAL A CG2 1 
ATOM   2202  N N   . LEU A 1 357 ? 119.433 97.771  122.556 1.00 60.77  ? 357 LEU A N   1 
ATOM   2203  C CA  . LEU A 1 357 ? 119.135 98.561  123.747 1.00 56.43  ? 357 LEU A CA  1 
ATOM   2204  C C   . LEU A 1 357 ? 119.955 98.100  124.959 1.00 62.16  ? 357 LEU A C   1 
ATOM   2205  O O   . LEU A 1 357 ? 120.537 98.926  125.653 1.00 67.67  ? 357 LEU A O   1 
ATOM   2206  C CB  . LEU A 1 357 ? 117.626 98.499  124.021 1.00 57.65  ? 357 LEU A CB  1 
ATOM   2207  C CG  . LEU A 1 357 ? 116.762 99.289  123.030 1.00 64.38  ? 357 LEU A CG  1 
ATOM   2208  C CD1 . LEU A 1 357 ? 115.296 99.086  123.393 1.00 67.91  ? 357 LEU A CD1 1 
ATOM   2209  C CD2 . LEU A 1 357 ? 117.080 100.779 123.087 1.00 61.92  ? 357 LEU A CD2 1 
ATOM   2210  N N   . GLU A 1 358 ? 120.069 96.790  125.189 1.00 74.43  ? 358 GLU A N   1 
ATOM   2211  C CA  . GLU A 1 358 ? 120.930 96.224  126.229 1.00 66.70  ? 358 GLU A CA  1 
ATOM   2212  C C   . GLU A 1 358 ? 122.404 96.589  126.017 1.00 67.83  ? 358 GLU A C   1 
ATOM   2213  O O   . GLU A 1 358 ? 123.094 96.986  126.948 1.00 83.17  ? 358 GLU A O   1 
ATOM   2214  C CB  . GLU A 1 358 ? 120.713 94.704  126.286 1.00 69.92  ? 358 GLU A CB  1 
ATOM   2215  C CG  . GLU A 1 358 ? 121.705 93.986  127.205 1.00 82.75  ? 358 GLU A CG  1 
ATOM   2216  C CD  . GLU A 1 358 ? 121.169 92.654  127.740 1.00 86.70  ? 358 GLU A CD  1 
ATOM   2217  O OE1 . GLU A 1 358 ? 120.767 91.789  126.933 1.00 86.01  ? 358 GLU A OE1 1 
ATOM   2218  O OE2 . GLU A 1 358 ? 121.166 92.480  128.980 1.00 85.48  ? 358 GLU A OE2 1 
ATOM   2219  N N   . ILE A 1 359 ? 122.879 96.535  124.781 1.00 59.62  ? 359 ILE A N   1 
ATOM   2220  C CA  . ILE A 1 359 ? 124.234 96.907  124.369 1.00 55.03  ? 359 ILE A CA  1 
ATOM   2221  C C   . ILE A 1 359 ? 124.550 98.374  124.659 1.00 61.96  ? 359 ILE A C   1 
ATOM   2222  O O   . ILE A 1 359 ? 125.568 98.646  125.286 1.00 84.17  ? 359 ILE A O   1 
ATOM   2223  C CB  . ILE A 1 359 ? 124.478 96.549  122.890 1.00 49.39  ? 359 ILE A CB  1 
ATOM   2224  C CG1 . ILE A 1 359 ? 124.588 95.022  122.740 1.00 56.90  ? 359 ILE A CG1 1 
ATOM   2225  C CG2 . ILE A 1 359 ? 125.753 97.206  122.352 1.00 58.96  ? 359 ILE A CG2 1 
ATOM   2226  C CD1 . ILE A 1 359 ? 124.529 94.538  121.298 1.00 56.10  ? 359 ILE A CD1 1 
ATOM   2227  N N   . ILE A 1 360 ? 123.717 99.332  124.255 1.00 57.87  ? 360 ILE A N   1 
ATOM   2228  C CA  . ILE A 1 360 ? 123.973 100.758 124.512 1.00 52.91  ? 360 ILE A CA  1 
ATOM   2229  C C   . ILE A 1 360 ? 123.997 101.036 126.014 1.00 65.30  ? 360 ILE A C   1 
ATOM   2230  O O   . ILE A 1 360 ? 124.860 101.768 126.498 1.00 77.56  ? 360 ILE A O   1 
ATOM   2231  C CB  . ILE A 1 360 ? 122.929 101.650 123.814 1.00 59.37  ? 360 ILE A CB  1 
ATOM   2232  C CG1 . ILE A 1 360 ? 123.051 101.531 122.288 1.00 58.80  ? 360 ILE A CG1 1 
ATOM   2233  C CG2 . ILE A 1 360 ? 123.082 103.119 124.234 1.00 59.81  ? 360 ILE A CG2 1 
ATOM   2234  C CD1 . ILE A 1 360 ? 121.796 101.998 121.561 1.00 57.86  ? 360 ILE A CD1 1 
ATOM   2235  N N   . ALA A 1 361 ? 123.060 100.456 126.753 1.00 64.11  ? 361 ALA A N   1 
ATOM   2236  C CA  . ALA A 1 361 ? 122.981 100.654 128.180 1.00 63.38  ? 361 ALA A CA  1 
ATOM   2237  C C   . ALA A 1 361 ? 124.187 100.025 128.901 1.00 64.22  ? 361 ALA A C   1 
ATOM   2238  O O   . ALA A 1 361 ? 124.845 100.710 129.674 1.00 67.29  ? 361 ALA A O   1 
ATOM   2239  C CB  . ALA A 1 361 ? 121.636 100.111 128.647 1.00 68.50  ? 361 ALA A CB  1 
ATOM   2240  N N   . PHE A 1 362 ? 124.510 98.759  128.625 1.00 72.86  ? 362 PHE A N   1 
ATOM   2241  C CA  . PHE A 1 362 ? 125.363 97.951  129.500 1.00 76.37  ? 362 PHE A CA  1 
ATOM   2242  C C   . PHE A 1 362 ? 126.669 97.428  128.889 1.00 76.15  ? 362 PHE A C   1 
ATOM   2243  O O   . PHE A 1 362 ? 127.556 97.050  129.648 1.00 85.79  ? 362 PHE A O   1 
ATOM   2244  C CB  . PHE A 1 362 ? 124.529 96.784  130.045 1.00 72.17  ? 362 PHE A CB  1 
ATOM   2245  C CG  . PHE A 1 362 ? 123.260 97.210  130.755 1.00 74.14  ? 362 PHE A CG  1 
ATOM   2246  C CD1 . PHE A 1 362 ? 123.331 97.869  131.992 1.00 79.87  ? 362 PHE A CD1 1 
ATOM   2247  C CD2 . PHE A 1 362 ? 122.009 96.974  130.170 1.00 74.99  ? 362 PHE A CD2 1 
ATOM   2248  C CE1 . PHE A 1 362 ? 122.157 98.307  132.625 1.00 75.55  ? 362 PHE A CE1 1 
ATOM   2249  C CE2 . PHE A 1 362 ? 120.835 97.419  130.799 1.00 76.61  ? 362 PHE A CE2 1 
ATOM   2250  C CZ  . PHE A 1 362 ? 120.911 98.095  132.020 1.00 75.45  ? 362 PHE A CZ  1 
ATOM   2251  N N   . HIS A 1 363 ? 126.827 97.364  127.565 1.00 68.85  ? 363 HIS A N   1 
ATOM   2252  C CA  . HIS A 1 363 ? 128.033 96.806  126.929 1.00 73.14  ? 363 HIS A CA  1 
ATOM   2253  C C   . HIS A 1 363 ? 128.895 97.845  126.205 1.00 76.67  ? 363 HIS A C   1 
ATOM   2254  O O   . HIS A 1 363 ? 130.072 97.600  125.961 1.00 77.65  ? 363 HIS A O   1 
ATOM   2255  C CB  . HIS A 1 363 ? 127.665 95.692  125.947 1.00 69.08  ? 363 HIS A CB  1 
ATOM   2256  C CG  . HIS A 1 363 ? 126.815 94.567  126.473 1.00 70.97  ? 363 HIS A CG  1 
ATOM   2257  N ND1 . HIS A 1 363 ? 126.213 93.615  125.657 1.00 83.77  ? 363 HIS A ND1 1 
ATOM   2258  C CD2 . HIS A 1 363 ? 126.545 94.256  127.770 1.00 78.05  ? 363 HIS A CD2 1 
ATOM   2259  C CE1 . HIS A 1 363 ? 125.562 92.776  126.475 1.00 79.97  ? 363 HIS A CE1 1 
ATOM   2260  N NE2 . HIS A 1 363 ? 125.745 93.138  127.752 1.00 80.44  ? 363 HIS A NE2 1 
ATOM   2261  N N   . CYS A 1 364 ? 128.332 98.991  125.848 1.00 70.95  ? 364 CYS A N   1 
ATOM   2262  C CA  . CYS A 1 364 ? 129.027 100.099 125.213 1.00 73.86  ? 364 CYS A CA  1 
ATOM   2263  C C   . CYS A 1 364 ? 129.885 100.882 126.225 1.00 80.60  ? 364 CYS A C   1 
ATOM   2264  O O   . CYS A 1 364 ? 129.378 101.275 127.267 1.00 78.85  ? 364 CYS A O   1 
ATOM   2265  C CB  . CYS A 1 364 ? 127.947 100.970 124.568 1.00 67.86  ? 364 CYS A CB  1 
ATOM   2266  S SG  . CYS A 1 364 ? 128.677 102.295 123.587 1.00 80.65  ? 364 CYS A SG  1 
ATOM   2267  N N   . LYS A 1 365 ? 131.168 101.153 125.936 1.00 90.59  ? 365 LYS A N   1 
ATOM   2268  C CA  . LYS A 1 365 ? 132.074 101.947 126.801 1.00 86.95  ? 365 LYS A CA  1 
ATOM   2269  C C   . LYS A 1 365 ? 132.059 103.458 126.542 1.00 88.71  ? 365 LYS A C   1 
ATOM   2270  O O   . LYS A 1 365 ? 132.626 104.223 127.317 1.00 95.80  ? 365 LYS A O   1 
ATOM   2271  C CB  . LYS A 1 365 ? 133.523 101.456 126.631 1.00 92.54  ? 365 LYS A CB  1 
ATOM   2272  C CG  . LYS A 1 365 ? 133.763 100.057 127.193 1.00 96.30  ? 365 LYS A CG  1 
ATOM   2273  C CD  . LYS A 1 365 ? 135.243 99.683  127.131 1.00 96.76  ? 365 LYS A CD  1 
ATOM   2274  C CE  . LYS A 1 365 ? 135.466 98.307  127.746 1.00 94.99  ? 365 LYS A CE  1 
ATOM   2275  N NZ  . LYS A 1 365 ? 136.887 97.925  127.748 1.00 94.43  ? 365 LYS A NZ  1 
ATOM   2276  N N   . SER A 1 366 ? 131.519 103.892 125.409 1.00 78.55  ? 366 SER A N   1 
ATOM   2277  C CA  . SER A 1 366 ? 131.837 105.194 124.798 1.00 80.43  ? 366 SER A CA  1 
ATOM   2278  C C   . SER A 1 366 ? 131.118 106.399 125.425 1.00 79.96  ? 366 SER A C   1 
ATOM   2279  O O   . SER A 1 366 ? 130.027 106.255 125.975 1.00 79.27  ? 366 SER A O   1 
ATOM   2280  C CB  . SER A 1 366 ? 131.537 105.140 123.302 1.00 77.02  ? 366 SER A CB  1 
ATOM   2281  O OG  . SER A 1 366 ? 130.143 105.133 123.084 1.00 78.57  ? 366 SER A OG  1 
ATOM   2282  N N   . PRO A 1 367 ? 131.652 107.628 125.266 1.00 83.72  ? 367 PRO A N   1 
ATOM   2283  C CA  . PRO A 1 367 ? 130.932 108.865 125.580 1.00 79.89  ? 367 PRO A CA  1 
ATOM   2284  C C   . PRO A 1 367 ? 129.612 109.030 124.819 1.00 77.43  ? 367 PRO A C   1 
ATOM   2285  O O   . PRO A 1 367 ? 128.739 109.780 125.237 1.00 77.18  ? 367 PRO A O   1 
ATOM   2286  C CB  . PRO A 1 367 ? 131.884 109.999 125.191 1.00 79.48  ? 367 PRO A CB  1 
ATOM   2287  C CG  . PRO A 1 367 ? 133.262 109.363 125.255 1.00 79.05  ? 367 PRO A CG  1 
ATOM   2288  C CD  . PRO A 1 367 ? 133.000 107.930 124.822 1.00 79.60  ? 367 PRO A CD  1 
ATOM   2289  N N   . ASN A 1 368 ? 129.469 108.363 123.671 1.00 90.09  ? 368 ASN A N   1 
ATOM   2290  C CA  . ASN A 1 368 ? 128.381 108.530 122.704 1.00 84.24  ? 368 ASN A CA  1 
ATOM   2291  C C   . ASN A 1 368 ? 127.040 107.901 123.110 1.00 78.84  ? 368 ASN A C   1 
ATOM   2292  O O   . ASN A 1 368 ? 126.044 108.132 122.434 1.00 85.32  ? 368 ASN A O   1 
ATOM   2293  C CB  . ASN A 1 368 ? 128.847 107.942 121.359 1.00 82.28  ? 368 ASN A CB  1 
ATOM   2294  C CG  . ASN A 1 368 ? 129.848 108.812 120.622 1.00 82.34  ? 368 ASN A CG  1 
ATOM   2295  O OD1 . ASN A 1 368 ? 129.955 110.010 120.820 1.00 84.85  ? 368 ASN A OD1 1 
ATOM   2296  N ND2 . ASN A 1 368 ? 130.619 108.240 119.739 1.00 81.44  ? 368 ASN A ND2 1 
ATOM   2297  N N   . ARG A 1 369 ? 126.962 107.104 124.179 1.00 69.69  ? 369 ARG A N   1 
ATOM   2298  C CA  . ARG A 1 369 ? 125.751 106.340 124.538 1.00 69.13  ? 369 ARG A CA  1 
ATOM   2299  C C   . ARG A 1 369 ? 124.514 107.202 124.687 1.00 71.92  ? 369 ARG A C   1 
ATOM   2300  O O   . ARG A 1 369 ? 123.444 106.826 124.226 1.00 67.72  ? 369 ARG A O   1 
ATOM   2301  C CB  . ARG A 1 369 ? 126.000 105.595 125.847 1.00 71.99  ? 369 ARG A CB  1 
ATOM   2302  C CG  . ARG A 1 369 ? 126.953 104.432 125.626 1.00 70.51  ? 369 ARG A CG  1 
ATOM   2303  C CD  . ARG A 1 369 ? 127.610 104.019 126.930 1.00 76.54  ? 369 ARG A CD  1 
ATOM   2304  N NE  . ARG A 1 369 ? 126.648 103.508 127.914 1.00 70.13  ? 369 ARG A NE  1 
ATOM   2305  C CZ  . ARG A 1 369 ? 126.454 103.991 129.123 1.00 69.22  ? 369 ARG A CZ  1 
ATOM   2306  N NH1 . ARG A 1 369 ? 125.683 103.405 129.978 1.00 76.06  ? 369 ARG A NH1 1 
ATOM   2307  N NH2 . ARG A 1 369 ? 127.009 105.086 129.539 1.00 69.68  ? 369 ARG A NH2 1 
ATOM   2308  N N   . HIS A 1 370 ? 124.650 108.374 125.295 1.00 78.64  ? 370 HIS A N   1 
ATOM   2309  C CA  . HIS A 1 370 ? 123.524 109.271 125.497 1.00 75.64  ? 370 HIS A CA  1 
ATOM   2310  C C   . HIS A 1 370 ? 122.988 109.868 124.189 1.00 74.83  ? 370 HIS A C   1 
ATOM   2311  O O   . HIS A 1 370 ? 121.799 110.140 124.091 1.00 77.47  ? 370 HIS A O   1 
ATOM   2312  C CB  . HIS A 1 370 ? 123.911 110.330 126.530 1.00 75.32  ? 370 HIS A CB  1 
ATOM   2313  C CG  . HIS A 1 370 ? 124.918 111.356 126.086 1.00 73.61  ? 370 HIS A CG  1 
ATOM   2314  N ND1 . HIS A 1 370 ? 124.645 112.503 125.388 1.00 70.71  ? 370 HIS A ND1 1 
ATOM   2315  C CD2 . HIS A 1 370 ? 126.257 111.350 126.348 1.00 76.62  ? 370 HIS A CD2 1 
ATOM   2316  C CE1 . HIS A 1 370 ? 125.788 113.181 125.236 1.00 75.52  ? 370 HIS A CE1 1 
ATOM   2317  N NE2 . HIS A 1 370 ? 126.805 112.514 125.801 1.00 80.09  ? 370 HIS A NE2 1 
ATOM   2318  N N   . ARG A 1 371 ? 123.820 109.995 123.147 1.00 80.75  ? 371 ARG A N   1 
ATOM   2319  C CA  . ARG A 1 371 ? 123.406 110.421 121.799 1.00 76.94  ? 371 ARG A CA  1 
ATOM   2320  C C   . ARG A 1 371 ? 122.712 109.309 121.019 1.00 73.77  ? 371 ARG A C   1 
ATOM   2321  O O   . ARG A 1 371 ? 121.897 109.596 120.158 1.00 75.01  ? 371 ARG A O   1 
ATOM   2322  C CB  . ARG A 1 371 ? 124.610 110.922 120.994 1.00 76.30  ? 371 ARG A CB  1 
ATOM   2323  C CG  . ARG A 1 371 ? 125.191 112.242 121.514 1.00 75.76  ? 371 ARG A CG  1 
ATOM   2324  C CD  . ARG A 1 371 ? 126.347 112.753 120.650 1.00 77.90  ? 371 ARG A CD  1 
ATOM   2325  N NE  . ARG A 1 371 ? 125.914 113.060 119.272 1.00 86.24  ? 371 ARG A NE  1 
ATOM   2326  C CZ  . ARG A 1 371 ? 126.672 113.134 118.192 1.00 85.33  ? 371 ARG A CZ  1 
ATOM   2327  N NH1 . ARG A 1 371 ? 126.133 113.307 117.026 1.00 79.36  ? 371 ARG A NH1 1 
ATOM   2328  N NH2 . ARG A 1 371 ? 127.967 113.031 118.242 1.00 83.05  ? 371 ARG A NH2 1 
ATOM   2329  N N   . MET A 1 372 ? 123.005 108.044 121.319 1.00 67.83  ? 372 MET A N   1 
ATOM   2330  C CA  . MET A 1 372 ? 122.382 106.887 120.667 1.00 58.64  ? 372 MET A CA  1 
ATOM   2331  C C   . MET A 1 372 ? 120.962 106.586 121.154 1.00 70.24  ? 372 MET A C   1 
ATOM   2332  O O   . MET A 1 372 ? 120.120 106.216 120.346 1.00 77.58  ? 372 MET A O   1 
ATOM   2333  C CB  . MET A 1 372 ? 123.270 105.647 120.818 1.00 65.77  ? 372 MET A CB  1 
ATOM   2334  C CG  . MET A 1 372 ? 124.594 105.829 120.076 1.00 71.31  ? 372 MET A CG  1 
ATOM   2335  S SD  . MET A 1 372 ? 125.566 104.325 119.876 1.00 70.26  ? 372 MET A SD  1 
ATOM   2336  C CE  . MET A 1 372 ? 126.165 104.102 121.555 1.00 73.42  ? 372 MET A CE  1 
ATOM   2337  N N   . VAL A 1 373 ? 120.632 106.776 122.427 1.00 74.15  ? 373 VAL A N   1 
ATOM   2338  C CA  . VAL A 1 373 ? 119.265 106.503 122.910 1.00 69.04  ? 373 VAL A CA  1 
ATOM   2339  C C   . VAL A 1 373 ? 118.232 107.538 122.467 1.00 68.68  ? 373 VAL A C   1 
ATOM   2340  O O   . VAL A 1 373 ? 117.038 107.282 122.558 1.00 73.89  ? 373 VAL A O   1 
ATOM   2341  C CB  . VAL A 1 373 ? 119.221 106.350 124.431 1.00 64.21  ? 373 VAL A CB  1 
ATOM   2342  C CG1 . VAL A 1 373 ? 120.047 105.151 124.881 1.00 68.05  ? 373 VAL A CG1 1 
ATOM   2343  C CG2 . VAL A 1 373 ? 119.710 107.598 125.147 1.00 68.50  ? 373 VAL A CG2 1 
ATOM   2344  N N   . VAL A 1 374 ? 118.660 108.712 121.996 1.00 68.31  ? 374 VAL A N   1 
ATOM   2345  C CA  . VAL A 1 374 ? 117.765 109.779 121.516 1.00 67.77  ? 374 VAL A CA  1 
ATOM   2346  C C   . VAL A 1 374 ? 117.534 109.740 120.000 1.00 74.31  ? 374 VAL A C   1 
ATOM   2347  O O   . VAL A 1 374 ? 116.834 110.596 119.465 1.00 78.48  ? 374 VAL A O   1 
ATOM   2348  C CB  . VAL A 1 374 ? 118.198 111.170 122.005 1.00 72.60  ? 374 VAL A CB  1 
ATOM   2349  C CG1 . VAL A 1 374 ? 118.212 111.226 123.530 1.00 76.06  ? 374 VAL A CG1 1 
ATOM   2350  C CG2 . VAL A 1 374 ? 119.563 111.614 121.491 1.00 69.89  ? 374 VAL A CG2 1 
ATOM   2351  N N   . LEU A 1 375 ? 118.021 108.730 119.267 1.00 69.84  ? 375 LEU A N   1 
ATOM   2352  C CA  . LEU A 1 375 ? 117.664 108.483 117.857 1.00 63.45  ? 375 LEU A CA  1 
ATOM   2353  C C   . LEU A 1 375 ? 116.295 107.803 117.705 1.00 67.28  ? 375 LEU A C   1 
ATOM   2354  O O   . LEU A 1 375 ? 115.917 107.012 118.555 1.00 78.47  ? 375 LEU A O   1 
ATOM   2355  C CB  . LEU A 1 375 ? 118.706 107.563 117.206 1.00 65.37  ? 375 LEU A CB  1 
ATOM   2356  C CG  . LEU A 1 375 ? 120.152 108.067 117.212 1.00 67.35  ? 375 LEU A CG  1 
ATOM   2357  C CD1 . LEU A 1 375 ? 121.013 107.074 116.447 1.00 65.25  ? 375 LEU A CD1 1 
ATOM   2358  C CD2 . LEU A 1 375 ? 120.269 109.432 116.559 1.00 66.72  ? 375 LEU A CD2 1 
ATOM   2359  N N   . GLU A 1 376 ? 115.564 108.012 116.610 1.00 70.56  ? 376 GLU A N   1 
ATOM   2360  C CA  . GLU A 1 376 ? 114.417 107.146 116.276 1.00 76.05  ? 376 GLU A CA  1 
ATOM   2361  C C   . GLU A 1 376 ? 114.875 105.826 115.627 1.00 74.54  ? 376 GLU A C   1 
ATOM   2362  O O   . GLU A 1 376 ? 115.849 105.834 114.879 1.00 76.41  ? 376 GLU A O   1 
ATOM   2363  C CB  . GLU A 1 376 ? 113.412 107.868 115.369 1.00 75.37  ? 376 GLU A CB  1 
ATOM   2364  C CG  . GLU A 1 376 ? 112.817 109.156 115.957 1.00 77.88  ? 376 GLU A CG  1 
ATOM   2365  C CD  . GLU A 1 376 ? 112.181 109.029 117.355 1.00 84.38  ? 376 GLU A CD  1 
ATOM   2366  O OE1 . GLU A 1 376 ? 111.802 107.916 117.775 1.00 90.91  ? 376 GLU A OE1 1 
ATOM   2367  O OE2 . GLU A 1 376 ? 112.069 110.074 118.036 1.00 82.97  ? 376 GLU A OE2 1 
ATOM   2368  N N   . PRO A 1 377 ? 114.198 104.689 115.875 1.00 60.92  ? 377 PRO A N   1 
ATOM   2369  C CA  . PRO A 1 377 ? 113.005 104.522 116.705 1.00 57.86  ? 377 PRO A CA  1 
ATOM   2370  C C   . PRO A 1 377 ? 113.274 104.454 118.217 1.00 67.26  ? 377 PRO A C   1 
ATOM   2371  O O   . PRO A 1 377 ? 112.321 104.424 118.984 1.00 79.49  ? 377 PRO A O   1 
ATOM   2372  C CB  . PRO A 1 377 ? 112.402 103.203 116.227 1.00 65.46  ? 377 PRO A CB  1 
ATOM   2373  C CG  . PRO A 1 377 ? 113.630 102.374 115.872 1.00 60.83  ? 377 PRO A CG  1 
ATOM   2374  C CD  . PRO A 1 377 ? 114.563 103.418 115.272 1.00 58.30  ? 377 PRO A CD  1 
ATOM   2375  N N   . LEU A 1 378 ? 114.531 104.398 118.671 1.00 70.54  ? 378 LEU A N   1 
ATOM   2376  C CA  . LEU A 1 378 ? 114.919 104.147 120.066 1.00 62.55  ? 378 LEU A CA  1 
ATOM   2377  C C   . LEU A 1 378 ? 114.299 105.131 121.061 1.00 66.86  ? 378 LEU A C   1 
ATOM   2378  O O   . LEU A 1 378 ? 113.818 104.712 122.105 1.00 75.14  ? 378 LEU A O   1 
ATOM   2379  C CB  . LEU A 1 378 ? 116.454 104.174 120.177 1.00 61.71  ? 378 LEU A CB  1 
ATOM   2380  C CG  . LEU A 1 378 ? 117.163 102.857 119.859 1.00 60.67  ? 378 LEU A CG  1 
ATOM   2381  C CD1 . LEU A 1 378 ? 116.793 102.257 118.532 1.00 63.63  ? 378 LEU A CD1 1 
ATOM   2382  C CD2 . LEU A 1 378 ? 118.656 103.074 119.875 1.00 65.71  ? 378 LEU A CD2 1 
ATOM   2383  N N   . ASN A 1 379 ? 114.253 106.415 120.737 1.00 66.18  ? 379 ASN A N   1 
ATOM   2384  C CA  . ASN A 1 379 ? 113.627 107.470 121.531 1.00 69.12  ? 379 ASN A CA  1 
ATOM   2385  C C   . ASN A 1 379 ? 112.137 107.203 121.805 1.00 72.00  ? 379 ASN A C   1 
ATOM   2386  O O   . ASN A 1 379 ? 111.755 107.092 122.973 1.00 77.25  ? 379 ASN A O   1 
ATOM   2387  C CB  . ASN A 1 379 ? 113.863 108.804 120.824 1.00 65.91  ? 379 ASN A CB  1 
ATOM   2388  C CG  . ASN A 1 379 ? 113.162 109.965 121.493 1.00 74.84  ? 379 ASN A CG  1 
ATOM   2389  O OD1 . ASN A 1 379 ? 113.233 110.157 122.701 1.00 78.41  ? 379 ASN A OD1 1 
ATOM   2390  N ND2 . ASN A 1 379 ? 112.445 110.755 120.734 1.00 74.98  ? 379 ASN A ND2 1 
ATOM   2391  N N   . LYS A 1 380 ? 111.297 107.031 120.773 1.00 69.47  ? 380 LYS A N   1 
ATOM   2392  C CA  . LYS A 1 380 ? 109.881 106.683 120.973 1.00 62.26  ? 380 LYS A CA  1 
ATOM   2393  C C   . LYS A 1 380 ? 109.705 105.287 121.580 1.00 66.16  ? 380 LYS A C   1 
ATOM   2394  O O   . LYS A 1 380 ? 108.834 105.106 122.417 1.00 76.22  ? 380 LYS A O   1 
ATOM   2395  C CB  . LYS A 1 380 ? 109.088 106.846 119.666 1.00 61.53  ? 380 LYS A CB  1 
ATOM   2396  C CG  . LYS A 1 380 ? 107.574 106.767 119.933 1.00 73.27  ? 380 LYS A CG  1 
ATOM   2397  C CD  . LYS A 1 380 ? 106.702 106.615 118.681 1.00 80.11  ? 380 LYS A CD  1 
ATOM   2398  C CE  . LYS A 1 380 ? 105.273 106.288 119.133 1.00 74.20  ? 380 LYS A CE  1 
ATOM   2399  N NZ  . LYS A 1 380 ? 104.338 106.089 118.001 1.00 63.73  ? 380 LYS A NZ  1 
ATOM   2400  N N   . LEU A 1 381 ? 110.538 104.311 121.235 1.00 61.22  ? 381 LEU A N   1 
ATOM   2401  C CA  . LEU A 1 381 ? 110.493 102.960 121.798 1.00 57.16  ? 381 LEU A CA  1 
ATOM   2402  C C   . LEU A 1 381 ? 110.808 102.919 123.306 1.00 65.36  ? 381 LEU A C   1 
ATOM   2403  O O   . LEU A 1 381 ? 110.160 102.193 124.053 1.00 72.56  ? 381 LEU A O   1 
ATOM   2404  C CB  . LEU A 1 381 ? 111.470 102.107 120.981 1.00 58.97  ? 381 LEU A CB  1 
ATOM   2405  C CG  . LEU A 1 381 ? 111.508 100.612 121.314 1.00 63.58  ? 381 LEU A CG  1 
ATOM   2406  C CD1 . LEU A 1 381 ? 110.157 99.951  121.072 1.00 63.77  ? 381 LEU A CD1 1 
ATOM   2407  C CD2 . LEU A 1 381 ? 112.530 99.946  120.405 1.00 64.14  ? 381 LEU A CD2 1 
ATOM   2408  N N   . LEU A 1 382 ? 111.766 103.715 123.786 1.00 62.74  ? 382 LEU A N   1 
ATOM   2409  C CA  . LEU A 1 382 ? 112.087 103.853 125.196 1.00 59.46  ? 382 LEU A CA  1 
ATOM   2410  C C   . LEU A 1 382 ? 111.068 104.724 125.930 1.00 63.14  ? 382 LEU A C   1 
ATOM   2411  O O   . LEU A 1 382 ? 110.804 104.464 127.096 1.00 71.67  ? 382 LEU A O   1 
ATOM   2412  C CB  . LEU A 1 382 ? 113.509 104.410 125.326 1.00 60.89  ? 382 LEU A CB  1 
ATOM   2413  C CG  . LEU A 1 382 ? 114.597 103.409 124.912 1.00 57.14  ? 382 LEU A CG  1 
ATOM   2414  C CD1 . LEU A 1 382 ? 115.910 104.151 124.718 1.00 55.24  ? 382 LEU A CD1 1 
ATOM   2415  C CD2 . LEU A 1 382 ? 114.765 102.320 125.965 1.00 66.99  ? 382 LEU A CD2 1 
ATOM   2416  N N   . GLN A 1 383 ? 110.447 105.707 125.276 1.00 66.78  ? 383 GLN A N   1 
ATOM   2417  C CA  . GLN A 1 383 ? 109.322 106.439 125.859 1.00 62.79  ? 383 GLN A CA  1 
ATOM   2418  C C   . GLN A 1 383 ? 108.098 105.538 126.050 1.00 70.93  ? 383 GLN A C   1 
ATOM   2419  O O   . GLN A 1 383 ? 107.480 105.555 127.103 1.00 80.68  ? 383 GLN A O   1 
ATOM   2420  C CB  . GLN A 1 383 ? 108.981 107.653 124.991 1.00 66.02  ? 383 GLN A CB  1 
ATOM   2421  C CG  . GLN A 1 383 ? 107.939 108.568 125.644 1.00 70.75  ? 383 GLN A CG  1 
ATOM   2422  C CD  . GLN A 1 383 ? 108.432 109.242 126.924 1.00 79.15  ? 383 GLN A CD  1 
ATOM   2423  O OE1 . GLN A 1 383 ? 109.510 109.823 126.978 1.00 84.66  ? 383 GLN A OE1 1 
ATOM   2424  N NE2 . GLN A 1 383 ? 107.681 109.216 127.994 1.00 73.97  ? 383 GLN A NE2 1 
ATOM   2425  N N   . GLU A 1 384 ? 107.761 104.717 125.059 1.00 69.62  ? 384 GLU A N   1 
ATOM   2426  C CA  . GLU A 1 384 ? 106.693 103.722 125.137 1.00 63.34  ? 384 GLU A CA  1 
ATOM   2427  C C   . GLU A 1 384 ? 106.919 102.712 126.266 1.00 71.67  ? 384 GLU A C   1 
ATOM   2428  O O   . GLU A 1 384 ? 106.002 102.428 127.028 1.00 75.12  ? 384 GLU A O   1 
ATOM   2429  C CB  . GLU A 1 384 ? 106.609 102.991 123.792 1.00 67.36  ? 384 GLU A CB  1 
ATOM   2430  C CG  . GLU A 1 384 ? 105.863 103.781 122.708 1.00 78.98  ? 384 GLU A CG  1 
ATOM   2431  C CD  . GLU A 1 384 ? 104.427 103.337 122.407 1.00 84.22  ? 384 GLU A CD  1 
ATOM   2432  O OE1 . GLU A 1 384 ? 103.961 102.281 122.891 1.00 86.08  ? 384 GLU A OE1 1 
ATOM   2433  O OE2 . GLU A 1 384 ? 103.754 104.052 121.652 1.00 77.41  ? 384 GLU A OE2 1 
ATOM   2434  N N   . LYS A 1 385 ? 108.143 102.200 126.430 1.00 77.50  ? 385 LYS A N   1 
ATOM   2435  C CA  . LYS A 1 385 ? 108.505 101.333 127.559 1.00 65.94  ? 385 LYS A CA  1 
ATOM   2436  C C   . LYS A 1 385 ? 108.442 102.073 128.894 1.00 65.41  ? 385 LYS A C   1 
ATOM   2437  O O   . LYS A 1 385 ? 107.903 101.537 129.854 1.00 72.13  ? 385 LYS A O   1 
ATOM   2438  C CB  . LYS A 1 385 ? 109.903 100.751 127.338 1.00 67.27  ? 385 LYS A CB  1 
ATOM   2439  C CG  . LYS A 1 385 ? 109.951 99.683  126.244 1.00 69.01  ? 385 LYS A CG  1 
ATOM   2440  C CD  . LYS A 1 385 ? 111.393 99.253  125.955 1.00 69.28  ? 385 LYS A CD  1 
ATOM   2441  C CE  . LYS A 1 385 ? 111.487 98.255  124.803 1.00 76.61  ? 385 LYS A CE  1 
ATOM   2442  N NZ  . LYS A 1 385 ? 110.785 96.994  125.080 1.00 66.90  ? 385 LYS A NZ  1 
ATOM   2443  N N   . TRP A 1 386 ? 108.948 103.301 128.977 1.00 65.35  ? 386 TRP A N   1 
ATOM   2444  C CA  . TRP A 1 386 ? 108.908 104.124 130.182 1.00 65.50  ? 386 TRP A CA  1 
ATOM   2445  C C   . TRP A 1 386 ? 107.478 104.387 130.643 1.00 66.38  ? 386 TRP A C   1 
ATOM   2446  O O   . TRP A 1 386 ? 107.155 104.156 131.797 1.00 75.97  ? 386 TRP A O   1 
ATOM   2447  C CB  . TRP A 1 386 ? 109.659 105.437 129.943 1.00 63.72  ? 386 TRP A CB  1 
ATOM   2448  C CG  . TRP A 1 386 ? 109.575 106.403 131.075 1.00 68.29  ? 386 TRP A CG  1 
ATOM   2449  C CD1 . TRP A 1 386 ? 108.784 107.496 131.120 1.00 69.23  ? 386 TRP A CD1 1 
ATOM   2450  C CD2 . TRP A 1 386 ? 110.204 106.308 132.383 1.00 73.63  ? 386 TRP A CD2 1 
ATOM   2451  N NE1 . TRP A 1 386 ? 108.890 108.089 132.362 1.00 70.90  ? 386 TRP A NE1 1 
ATOM   2452  C CE2 . TRP A 1 386 ? 109.733 107.381 133.188 1.00 73.13  ? 386 TRP A CE2 1 
ATOM   2453  C CE3 . TRP A 1 386 ? 111.087 105.393 132.986 1.00 70.63  ? 386 TRP A CE3 1 
ATOM   2454  C CZ2 . TRP A 1 386 ? 110.125 107.534 134.520 1.00 69.39  ? 386 TRP A CZ2 1 
ATOM   2455  C CZ3 . TRP A 1 386 ? 111.493 105.544 134.320 1.00 64.50  ? 386 TRP A CZ3 1 
ATOM   2456  C CH2 . TRP A 1 386 ? 111.018 106.612 135.085 1.00 68.30  ? 386 TRP A CH2 1 
ATOM   2457  N N   . ASP A 1 387 ? 106.582 104.765 129.743 1.00 66.34  ? 387 ASP A N   1 
ATOM   2458  C CA  . ASP A 1 387 ? 105.162 104.982 130.033 1.00 66.65  ? 387 ASP A CA  1 
ATOM   2459  C C   . ASP A 1 387 ? 104.464 103.722 130.578 1.00 69.13  ? 387 ASP A C   1 
ATOM   2460  O O   . ASP A 1 387 ? 103.598 103.823 131.442 1.00 75.06  ? 387 ASP A O   1 
ATOM   2461  C CB  . ASP A 1 387 ? 104.436 105.465 128.770 1.00 74.51  ? 387 ASP A CB  1 
ATOM   2462  C CG  . ASP A 1 387 ? 104.868 106.836 128.236 1.00 77.05  ? 387 ASP A CG  1 
ATOM   2463  O OD1 . ASP A 1 387 ? 105.574 107.592 128.938 1.00 71.85  ? 387 ASP A OD1 1 
ATOM   2464  O OD2 . ASP A 1 387 ? 104.426 107.195 127.123 1.00 75.68  ? 387 ASP A OD2 1 
ATOM   2465  N N   . ARG A 1 388 ? 104.835 102.526 130.106 1.00 80.32  ? 388 ARG A N   1 
ATOM   2466  C CA  . ARG A 1 388 ? 104.347 101.249 130.652 1.00 78.76  ? 388 ARG A CA  1 
ATOM   2467  C C   . ARG A 1 388 ? 104.930 100.895 132.021 1.00 85.00  ? 388 ARG A C   1 
ATOM   2468  O O   . ARG A 1 388 ? 104.355 100.001 132.671 1.00 83.99  ? 388 ARG A O   1 
ATOM   2469  C CB  . ARG A 1 388 ? 104.582 100.110 129.643 1.00 78.62  ? 388 ARG A CB  1 
ATOM   2470  C CG  . ARG A 1 388 ? 103.620 100.222 128.454 1.00 85.28  ? 388 ARG A CG  1 
ATOM   2471  C CD  . ARG A 1 388 ? 103.620 98.988  127.531 1.00 84.40  ? 388 ARG A CD  1 
ATOM   2472  N NE  . ARG A 1 388 ? 104.933 98.944  126.905 1.00 90.38  ? 388 ARG A NE  1 
ATOM   2473  C CZ  . ARG A 1 388 ? 105.318 99.754  125.925 1.00 95.63  ? 388 ARG A CZ  1 
ATOM   2474  N NH1 . ARG A 1 388 ? 106.538 99.657  125.425 1.00 90.77  ? 388 ARG A NH1 1 
ATOM   2475  N NH2 . ARG A 1 388 ? 104.487 100.666 125.455 1.00 90.09  ? 388 ARG A NH2 1 
ATOM   2476  N N   . LEU A 1 389 ? 106.015 101.539 132.454 1.00 78.44  ? 389 LEU A N   1 
ATOM   2477  C CA  . LEU A 1 389 ? 106.778 101.188 133.658 1.00 66.38  ? 389 LEU A CA  1 
ATOM   2478  C C   . LEU A 1 389 ? 106.900 102.316 134.692 1.00 70.34  ? 389 LEU A C   1 
ATOM   2479  O O   . LEU A 1 389 ? 107.324 102.048 135.808 1.00 81.19  ? 389 LEU A O   1 
ATOM   2480  C CB  . LEU A 1 389 ? 108.160 100.672 133.238 1.00 68.35  ? 389 LEU A CB  1 
ATOM   2481  C CG  . LEU A 1 389 ? 108.147 99.335  132.480 1.00 71.97  ? 389 LEU A CG  1 
ATOM   2482  C CD1 . LEU A 1 389 ? 109.510 99.089  131.851 1.00 71.14  ? 389 LEU A CD1 1 
ATOM   2483  C CD2 . LEU A 1 389 ? 107.826 98.164  133.404 1.00 66.83  ? 389 LEU A CD2 1 
ATOM   2484  N N   . VAL A 1 390 ? 106.492 103.551 134.401 1.00 71.13  ? 390 VAL A N   1 
ATOM   2485  C CA  . VAL A 1 390 ? 106.589 104.703 135.309 1.00 71.05  ? 390 VAL A CA  1 
ATOM   2486  C C   . VAL A 1 390 ? 105.845 104.480 136.635 1.00 76.47  ? 390 VAL A C   1 
ATOM   2487  O O   . VAL A 1 390 ? 106.324 104.864 137.696 1.00 78.84  ? 390 VAL A O   1 
ATOM   2488  C CB  . VAL A 1 390 ? 106.161 105.977 134.561 1.00 63.94  ? 390 VAL A CB  1 
ATOM   2489  C CG1 . VAL A 1 390 ? 104.679 106.003 134.192 1.00 67.98  ? 390 VAL A CG1 1 
ATOM   2490  C CG2 . VAL A 1 390 ? 106.471 107.236 135.360 1.00 69.65  ? 390 VAL A CG2 1 
ATOM   2491  N N   . SER A 1 391 ? 104.731 103.749 136.626 1.00 77.10  ? 391 SER A N   1 
ATOM   2492  C CA  . SER A 1 391 ? 104.015 103.331 137.838 1.00 70.17  ? 391 SER A CA  1 
ATOM   2493  C C   . SER A 1 391 ? 104.770 102.275 138.653 1.00 74.56  ? 391 SER A C   1 
ATOM   2494  O O   . SER A 1 391 ? 104.667 102.272 139.878 1.00 87.90  ? 391 SER A O   1 
ATOM   2495  C CB  . SER A 1 391 ? 102.635 102.798 137.457 1.00 73.69  ? 391 SER A CB  1 
ATOM   2496  O OG  . SER A 1 391 ? 102.753 101.688 136.589 1.00 81.83  ? 391 SER A OG  1 
ATOM   2497  N N   . ARG A 1 392 ? 105.587 101.427 138.021 1.00 74.12  ? 392 ARG A N   1 
ATOM   2498  C CA  . ARG A 1 392 ? 106.503 100.489 138.695 1.00 63.71  ? 392 ARG A CA  1 
ATOM   2499  C C   . ARG A 1 392 ? 107.708 101.223 139.274 1.00 71.05  ? 392 ARG A C   1 
ATOM   2500  O O   . ARG A 1 392 ? 108.113 100.946 140.392 1.00 88.30  ? 392 ARG A O   1 
ATOM   2501  C CB  . ARG A 1 392 ? 106.937 99.396  137.710 1.00 70.73  ? 392 ARG A CB  1 
ATOM   2502  C CG  . ARG A 1 392 ? 107.400 98.130  138.433 1.00 69.16  ? 392 ARG A CG  1 
ATOM   2503  C CD  . ARG A 1 392 ? 107.799 97.053  137.414 1.00 82.01  ? 392 ARG A CD  1 
ATOM   2504  N NE  . ARG A 1 392 ? 107.830 95.711  138.020 1.00 87.69  ? 392 ARG A NE  1 
ATOM   2505  C CZ  . ARG A 1 392 ? 106.804 94.891  138.174 1.00 92.58  ? 392 ARG A CZ  1 
ATOM   2506  N NH1 . ARG A 1 392 ? 106.965 93.715  138.704 1.00 88.09  ? 392 ARG A NH1 1 
ATOM   2507  N NH2 . ARG A 1 392 ? 105.597 95.204  137.807 1.00 88.13  ? 392 ARG A NH2 1 
ATOM   2508  N N   . PHE A 1 393 ? 108.229 102.221 138.571 1.00 62.33  ? 393 PHE A N   1 
ATOM   2509  C CA  . PHE A 1 393 ? 109.295 103.090 139.053 1.00 55.11  ? 393 PHE A CA  1 
ATOM   2510  C C   . PHE A 1 393 ? 108.885 103.833 140.325 1.00 65.53  ? 393 PHE A C   1 
ATOM   2511  O O   . PHE A 1 393 ? 109.612 103.809 141.314 1.00 77.66  ? 393 PHE A O   1 
ATOM   2512  C CB  . PHE A 1 393 ? 109.697 104.064 137.946 1.00 56.92  ? 393 PHE A CB  1 
ATOM   2513  C CG  . PHE A 1 393 ? 110.902 104.901 138.294 1.00 60.48  ? 393 PHE A CG  1 
ATOM   2514  C CD1 . PHE A 1 393 ? 112.193 104.379 138.100 1.00 67.83  ? 393 PHE A CD1 1 
ATOM   2515  C CD2 . PHE A 1 393 ? 110.746 106.194 138.819 1.00 57.70  ? 393 PHE A CD2 1 
ATOM   2516  C CE1 . PHE A 1 393 ? 113.317 105.154 138.414 1.00 62.48  ? 393 PHE A CE1 1 
ATOM   2517  C CE2 . PHE A 1 393 ? 111.872 106.964 139.136 1.00 62.25  ? 393 PHE A CE2 1 
ATOM   2518  C CZ  . PHE A 1 393 ? 113.157 106.448 138.919 1.00 58.32  ? 393 PHE A CZ  1 
ATOM   2519  N N   . PHE A 1 394 ? 107.697 104.445 140.349 1.00 71.25  ? 394 PHE A N   1 
ATOM   2520  C CA  . PHE A 1 394 ? 107.226 105.159 141.532 1.00 66.07  ? 394 PHE A CA  1 
ATOM   2521  C C   . PHE A 1 394 ? 106.689 104.256 142.650 1.00 62.38  ? 394 PHE A C   1 
ATOM   2522  O O   . PHE A 1 394 ? 106.797 104.620 143.814 1.00 77.72  ? 394 PHE A O   1 
ATOM   2523  C CB  . PHE A 1 394 ? 106.285 106.288 141.122 1.00 63.62  ? 394 PHE A CB  1 
ATOM   2524  C CG  . PHE A 1 394 ? 107.027 107.407 140.411 1.00 74.04  ? 394 PHE A CG  1 
ATOM   2525  C CD1 . PHE A 1 394 ? 108.036 108.113 141.088 1.00 72.56  ? 394 PHE A CD1 1 
ATOM   2526  C CD2 . PHE A 1 394 ? 106.743 107.728 139.074 1.00 66.45  ? 394 PHE A CD2 1 
ATOM   2527  C CE1 . PHE A 1 394 ? 108.766 109.119 140.439 1.00 69.15  ? 394 PHE A CE1 1 
ATOM   2528  C CE2 . PHE A 1 394 ? 107.462 108.745 138.426 1.00 65.36  ? 394 PHE A CE2 1 
ATOM   2529  C CZ  . PHE A 1 394 ? 108.468 109.440 139.108 1.00 70.08  ? 394 PHE A CZ  1 
ATOM   2530  N N   . PHE A 1 395 ? 106.208 103.052 142.353 1.00 60.95  ? 395 PHE A N   1 
ATOM   2531  C CA  . PHE A 1 395 ? 105.985 102.028 143.370 1.00 62.88  ? 395 PHE A CA  1 
ATOM   2532  C C   . PHE A 1 395 ? 107.297 101.618 144.049 1.00 69.35  ? 395 PHE A C   1 
ATOM   2533  O O   . PHE A 1 395 ? 107.385 101.618 145.275 1.00 81.93  ? 395 PHE A O   1 
ATOM   2534  C CB  . PHE A 1 395 ? 105.282 100.834 142.723 1.00 65.10  ? 395 PHE A CB  1 
ATOM   2535  C CG  . PHE A 1 395 ? 105.080 99.658  143.652 1.00 69.40  ? 395 PHE A CG  1 
ATOM   2536  C CD1 . PHE A 1 395 ? 104.124 99.728  144.677 1.00 75.73  ? 395 PHE A CD1 1 
ATOM   2537  C CD2 . PHE A 1 395 ? 105.844 98.493  143.488 1.00 69.17  ? 395 PHE A CD2 1 
ATOM   2538  C CE1 . PHE A 1 395 ? 103.934 98.636  145.537 1.00 73.63  ? 395 PHE A CE1 1 
ATOM   2539  C CE2 . PHE A 1 395 ? 105.644 97.397  144.339 1.00 74.04  ? 395 PHE A CE2 1 
ATOM   2540  C CZ  . PHE A 1 395 ? 104.689 97.467  145.363 1.00 74.80  ? 395 PHE A CZ  1 
ATOM   2541  N N   . ASN A 1 396 ? 108.353 101.354 143.281 1.00 69.09  ? 396 ASN A N   1 
ATOM   2542  C CA  . ASN A 1 396 ? 109.675 101.029 143.806 1.00 64.78  ? 396 ASN A CA  1 
ATOM   2543  C C   . ASN A 1 396 ? 110.260 102.152 144.685 1.00 70.02  ? 396 ASN A C   1 
ATOM   2544  O O   . ASN A 1 396 ? 110.847 101.875 145.728 1.00 77.50  ? 396 ASN A O   1 
ATOM   2545  C CB  . ASN A 1 396 ? 110.607 100.719 142.626 1.00 69.06  ? 396 ASN A CB  1 
ATOM   2546  C CG  . ASN A 1 396 ? 110.322 99.414  141.900 1.00 72.77  ? 396 ASN A CG  1 
ATOM   2547  O OD1 . ASN A 1 396 ? 109.418 98.653  142.204 1.00 75.36  ? 396 ASN A OD1 1 
ATOM   2548  N ND2 . ASN A 1 396 ? 111.140 99.073  140.936 1.00 73.51  ? 396 ASN A ND2 1 
ATOM   2549  N N   . PHE A 1 397 ? 110.048 103.412 144.306 1.00 58.12  ? 397 PHE A N   1 
ATOM   2550  C CA  . PHE A 1 397 ? 110.352 104.604 145.099 1.00 58.37  ? 397 PHE A CA  1 
ATOM   2551  C C   . PHE A 1 397 ? 109.548 104.694 146.400 1.00 65.29  ? 397 PHE A C   1 
ATOM   2552  O O   . PHE A 1 397 ? 110.126 104.970 147.445 1.00 73.03  ? 397 PHE A O   1 
ATOM   2553  C CB  . PHE A 1 397 ? 110.091 105.841 144.244 1.00 55.63  ? 397 PHE A CB  1 
ATOM   2554  C CG  . PHE A 1 397 ? 110.159 107.172 144.968 1.00 64.70  ? 397 PHE A CG  1 
ATOM   2555  C CD1 . PHE A 1 397 ? 111.330 107.562 145.636 1.00 64.79  ? 397 PHE A CD1 1 
ATOM   2556  C CD2 . PHE A 1 397 ? 109.048 108.032 144.963 1.00 69.09  ? 397 PHE A CD2 1 
ATOM   2557  C CE1 . PHE A 1 397 ? 111.409 108.816 146.252 1.00 56.18  ? 397 PHE A CE1 1 
ATOM   2558  C CE2 . PHE A 1 397 ? 109.119 109.281 145.597 1.00 67.92  ? 397 PHE A CE2 1 
ATOM   2559  C CZ  . PHE A 1 397 ? 110.303 109.676 146.232 1.00 65.24  ? 397 PHE A CZ  1 
ATOM   2560  N N   . ALA A 1 398 ? 108.238 104.440 146.373 1.00 69.65  ? 398 ALA A N   1 
ATOM   2561  C CA  . ALA A 1 398 ? 107.384 104.458 147.555 1.00 56.41  ? 398 ALA A CA  1 
ATOM   2562  C C   . ALA A 1 398 ? 107.733 103.346 148.557 1.00 62.99  ? 398 ALA A C   1 
ATOM   2563  O O   . ALA A 1 398 ? 107.785 103.606 149.754 1.00 83.39  ? 398 ALA A O   1 
ATOM   2564  C CB  . ALA A 1 398 ? 105.930 104.376 147.104 1.00 55.94  ? 398 ALA A CB  1 
ATOM   2565  N N   . CYS A 1 399 ? 108.056 102.132 148.109 1.00 59.27  ? 399 CYS A N   1 
ATOM   2566  C CA  . CYS A 1 399 ? 108.596 101.093 148.990 1.00 67.71  ? 399 CYS A CA  1 
ATOM   2567  C C   . CYS A 1 399 ? 109.903 101.527 149.661 1.00 66.36  ? 399 CYS A C   1 
ATOM   2568  O O   . CYS A 1 399 ? 110.088 101.290 150.851 1.00 76.94  ? 399 CYS A O   1 
ATOM   2569  C CB  . CYS A 1 399 ? 108.848 99.825  148.182 1.00 71.04  ? 399 CYS A CB  1 
ATOM   2570  S SG  . CYS A 1 399 ? 107.295 99.060  147.688 1.00 72.59  ? 399 CYS A SG  1 
ATOM   2571  N N   . TYR A 1 400 ? 110.781 102.185 148.912 1.00 54.62  ? 400 TYR A N   1 
ATOM   2572  C CA  . TYR A 1 400 ? 112.048 102.654 149.438 1.00 51.92  ? 400 TYR A CA  1 
ATOM   2573  C C   . TYR A 1 400 ? 111.873 103.852 150.384 1.00 65.12  ? 400 TYR A C   1 
ATOM   2574  O O   . TYR A 1 400 ? 112.543 103.912 151.405 1.00 80.26  ? 400 TYR A O   1 
ATOM   2575  C CB  . TYR A 1 400 ? 112.986 102.934 148.275 1.00 57.47  ? 400 TYR A CB  1 
ATOM   2576  C CG  . TYR A 1 400 ? 114.406 103.158 148.729 1.00 62.86  ? 400 TYR A CG  1 
ATOM   2577  C CD1 . TYR A 1 400 ? 115.232 102.067 149.039 1.00 59.80  ? 400 TYR A CD1 1 
ATOM   2578  C CD2 . TYR A 1 400 ? 114.874 104.466 148.895 1.00 57.33  ? 400 TYR A CD2 1 
ATOM   2579  C CE1 . TYR A 1 400 ? 116.528 102.295 149.529 1.00 51.09  ? 400 TYR A CE1 1 
ATOM   2580  C CE2 . TYR A 1 400 ? 116.166 104.702 149.372 1.00 50.80  ? 400 TYR A CE2 1 
ATOM   2581  C CZ  . TYR A 1 400 ? 116.986 103.610 149.698 1.00 53.91  ? 400 TYR A CZ  1 
ATOM   2582  O OH  . TYR A 1 400 ? 118.204 103.834 150.224 1.00 66.93  ? 400 TYR A OH  1 
ATOM   2583  N N   . LEU A 1 401 ? 110.912 104.751 150.152 1.00 55.25  ? 401 LEU A N   1 
ATOM   2584  C CA  . LEU A 1 401 ? 110.504 105.770 151.118 1.00 48.34  ? 401 LEU A CA  1 
ATOM   2585  C C   . LEU A 1 401 ? 109.993 105.152 152.424 1.00 55.61  ? 401 LEU A C   1 
ATOM   2586  O O   . LEU A 1 401 ? 110.391 105.585 153.494 1.00 71.64  ? 401 LEU A O   1 
ATOM   2587  C CB  . LEU A 1 401 ? 109.372 106.633 150.543 1.00 63.08  ? 401 LEU A CB  1 
ATOM   2588  C CG  . LEU A 1 401 ? 109.777 107.825 149.686 1.00 66.12  ? 401 LEU A CG  1 
ATOM   2589  C CD1 . LEU A 1 401 ? 108.503 108.453 149.128 1.00 62.24  ? 401 LEU A CD1 1 
ATOM   2590  C CD2 . LEU A 1 401 ? 110.486 108.896 150.510 1.00 62.20  ? 401 LEU A CD2 1 
ATOM   2591  N N   . VAL A 1 402 ? 109.121 104.148 152.364 1.00 58.65  ? 402 VAL A N   1 
ATOM   2592  C CA  . VAL A 1 402 ? 108.582 103.448 153.541 1.00 62.73  ? 402 VAL A CA  1 
ATOM   2593  C C   . VAL A 1 402 ? 109.680 102.715 154.304 1.00 64.13  ? 402 VAL A C   1 
ATOM   2594  O O   . VAL A 1 402 ? 109.730 102.794 155.524 1.00 74.10  ? 402 VAL A O   1 
ATOM   2595  C CB  . VAL A 1 402 ? 107.442 102.497 153.139 1.00 62.15  ? 402 VAL A CB  1 
ATOM   2596  C CG1 . VAL A 1 402 ? 107.012 101.575 154.281 1.00 69.06  ? 402 VAL A CG1 1 
ATOM   2597  C CG2 . VAL A 1 402 ? 106.220 103.310 152.714 1.00 57.83  ? 402 VAL A CG2 1 
ATOM   2598  N N   . TYR A 1 403 ? 110.594 102.041 153.605 1.00 64.93  ? 403 TYR A N   1 
ATOM   2599  C CA  . TYR A 1 403 ? 111.790 101.448 154.195 1.00 56.12  ? 403 TYR A CA  1 
ATOM   2600  C C   . TYR A 1 403 ? 112.668 102.513 154.857 1.00 61.37  ? 403 TYR A C   1 
ATOM   2601  O O   . TYR A 1 403 ? 113.046 102.335 156.007 1.00 79.53  ? 403 TYR A O   1 
ATOM   2602  C CB  . TYR A 1 403 ? 112.539 100.656 153.118 1.00 67.58  ? 403 TYR A CB  1 
ATOM   2603  C CG  . TYR A 1 403 ? 113.967 100.241 153.430 1.00 70.42  ? 403 TYR A CG  1 
ATOM   2604  C CD1 . TYR A 1 403 ? 114.238 99.186  154.323 1.00 61.54  ? 403 TYR A CD1 1 
ATOM   2605  C CD2 . TYR A 1 403 ? 115.030 100.883 152.771 1.00 72.54  ? 403 TYR A CD2 1 
ATOM   2606  C CE1 . TYR A 1 403 ? 115.567 98.771  154.543 1.00 58.00  ? 403 TYR A CE1 1 
ATOM   2607  C CE2 . TYR A 1 403 ? 116.355 100.474 152.988 1.00 66.42  ? 403 TYR A CE2 1 
ATOM   2608  C CZ  . TYR A 1 403 ? 116.625 99.407  153.865 1.00 63.57  ? 403 TYR A CZ  1 
ATOM   2609  O OH  . TYR A 1 403 ? 117.900 98.980  154.036 1.00 74.72  ? 403 TYR A OH  1 
ATOM   2610  N N   . MET A 1 404 ? 112.926 103.653 154.212 1.00 55.75  ? 404 MET A N   1 
ATOM   2611  C CA  . MET A 1 404 ? 113.704 104.743 154.811 1.00 65.40  ? 404 MET A CA  1 
ATOM   2612  C C   . MET A 1 404 ? 112.987 105.507 155.932 1.00 70.48  ? 404 MET A C   1 
ATOM   2613  O O   . MET A 1 404 ? 113.646 105.994 156.849 1.00 78.00  ? 404 MET A O   1 
ATOM   2614  C CB  . MET A 1 404 ? 114.209 105.706 153.730 1.00 54.05  ? 404 MET A CB  1 
ATOM   2615  C CG  . MET A 1 404 ? 115.354 105.112 152.908 1.00 61.50  ? 404 MET A CG  1 
ATOM   2616  S SD  . MET A 1 404 ? 116.735 104.373 153.831 1.00 63.28  ? 404 MET A SD  1 
ATOM   2617  C CE  . MET A 1 404 ? 117.154 105.695 154.987 1.00 69.76  ? 404 MET A CE  1 
ATOM   2618  N N   . PHE A 1 405 ? 111.660 105.568 155.937 1.00 66.03  ? 405 PHE A N   1 
ATOM   2619  C CA  . PHE A 1 405 ? 110.877 106.061 157.068 1.00 65.96  ? 405 PHE A CA  1 
ATOM   2620  C C   . PHE A 1 405 ? 111.049 105.150 158.291 1.00 68.62  ? 405 PHE A C   1 
ATOM   2621  O O   . PHE A 1 405 ? 111.470 105.621 159.344 1.00 73.67  ? 405 PHE A O   1 
ATOM   2622  C CB  . PHE A 1 405 ? 109.411 106.194 156.644 1.00 62.93  ? 405 PHE A CB  1 
ATOM   2623  C CG  . PHE A 1 405 ? 108.470 106.608 157.754 1.00 77.51  ? 405 PHE A CG  1 
ATOM   2624  C CD1 . PHE A 1 405 ? 108.279 107.966 158.053 1.00 78.09  ? 405 PHE A CD1 1 
ATOM   2625  C CD2 . PHE A 1 405 ? 107.792 105.629 158.501 1.00 80.06  ? 405 PHE A CD2 1 
ATOM   2626  C CE1 . PHE A 1 405 ? 107.427 108.347 159.103 1.00 77.43  ? 405 PHE A CE1 1 
ATOM   2627  C CE2 . PHE A 1 405 ? 106.949 106.007 159.557 1.00 75.06  ? 405 PHE A CE2 1 
ATOM   2628  C CZ  . PHE A 1 405 ? 106.766 107.366 159.858 1.00 75.07  ? 405 PHE A CZ  1 
ATOM   2629  N N   . ILE A 1 406 ? 110.825 103.840 158.142 1.00 68.69  ? 406 ILE A N   1 
ATOM   2630  C CA  . ILE A 1 406 ? 111.044 102.824 159.175 1.00 65.33  ? 406 ILE A CA  1 
ATOM   2631  C C   . ILE A 1 406 ? 112.502 102.843 159.647 1.00 69.17  ? 406 ILE A C   1 
ATOM   2632  O O   . ILE A 1 406 ? 112.742 102.869 160.847 1.00 87.94  ? 406 ILE A O   1 
ATOM   2633  C CB  . ILE A 1 406 ? 110.607 101.432 158.670 1.00 67.21  ? 406 ILE A CB  1 
ATOM   2634  C CG1 . ILE A 1 406 ? 109.082 101.396 158.450 1.00 68.58  ? 406 ILE A CG1 1 
ATOM   2635  C CG2 . ILE A 1 406 ? 111.012 100.316 159.642 1.00 68.28  ? 406 ILE A CG2 1 
ATOM   2636  C CD1 . ILE A 1 406 ? 108.626 100.238 157.563 1.00 74.99  ? 406 ILE A CD1 1 
ATOM   2637  N N   . PHE A 1 407 ? 113.477 102.914 158.740 1.00 60.96  ? 407 PHE A N   1 
ATOM   2638  C CA  . PHE A 1 407 ? 114.890 103.028 159.092 1.00 67.32  ? 407 PHE A CA  1 
ATOM   2639  C C   . PHE A 1 407 ? 115.137 104.239 159.992 1.00 79.83  ? 407 PHE A C   1 
ATOM   2640  O O   . PHE A 1 407 ? 115.829 104.141 161.000 1.00 84.43  ? 407 PHE A O   1 
ATOM   2641  C CB  . PHE A 1 407 ? 115.729 103.111 157.811 1.00 71.22  ? 407 PHE A CB  1 
ATOM   2642  C CG  . PHE A 1 407 ? 117.103 102.489 157.896 1.00 76.40  ? 407 PHE A CG  1 
ATOM   2643  C CD1 . PHE A 1 407 ? 118.075 102.971 158.787 1.00 75.16  ? 407 PHE A CD1 1 
ATOM   2644  C CD2 . PHE A 1 407 ? 117.411 101.403 157.068 1.00 76.93  ? 407 PHE A CD2 1 
ATOM   2645  C CE1 . PHE A 1 407 ? 119.338 102.369 158.846 1.00 73.49  ? 407 PHE A CE1 1 
ATOM   2646  C CE2 . PHE A 1 407 ? 118.669 100.800 157.135 1.00 74.88  ? 407 PHE A CE2 1 
ATOM   2647  C CZ  . PHE A 1 407 ? 119.635 101.276 158.025 1.00 70.98  ? 407 PHE A CZ  1 
ATOM   2648  N N   . THR A 1 408 ? 114.539 105.384 159.671 1.00 75.99  ? 408 THR A N   1 
ATOM   2649  C CA  . THR A 1 408 ? 114.731 106.636 160.411 1.00 73.29  ? 408 THR A CA  1 
ATOM   2650  C C   . THR A 1 408 ? 114.062 106.620 161.786 1.00 73.79  ? 408 THR A C   1 
ATOM   2651  O O   . THR A 1 408 ? 114.694 107.003 162.760 1.00 79.83  ? 408 THR A O   1 
ATOM   2652  C CB  . THR A 1 408 ? 114.232 107.811 159.567 1.00 67.06  ? 408 THR A CB  1 
ATOM   2653  O OG1 . THR A 1 408 ? 114.914 107.800 158.341 1.00 69.35  ? 408 THR A OG1 1 
ATOM   2654  C CG2 . THR A 1 408 ? 114.487 109.169 160.198 1.00 64.39  ? 408 THR A CG2 1 
ATOM   2655  N N   . VAL A 1 409 ? 112.827 106.126 161.885 1.00 66.22  ? 409 VAL A N   1 
ATOM   2656  C CA  . VAL A 1 409 ? 112.012 105.965 163.091 1.00 68.55  ? 409 VAL A CA  1 
ATOM   2657  C C   . VAL A 1 409 ? 112.577 104.906 164.042 1.00 71.93  ? 409 VAL A C   1 
ATOM   2658  O O   . VAL A 1 409 ? 112.203 104.912 165.210 1.00 83.55  ? 409 VAL A O   1 
ATOM   2659  C CB  . VAL A 1 409 ? 110.557 105.680 162.668 1.00 74.79  ? 409 VAL A CB  1 
ATOM   2660  C CG1 . VAL A 1 409 ? 109.610 105.228 163.779 1.00 76.28  ? 409 VAL A CG1 1 
ATOM   2661  C CG2 . VAL A 1 409 ? 109.957 106.965 162.089 1.00 70.40  ? 409 VAL A CG2 1 
ATOM   2662  N N   . VAL A 1 410 ? 113.454 104.020 163.563 1.00 72.91  ? 410 VAL A N   1 
ATOM   2663  C CA  . VAL A 1 410 ? 114.185 103.016 164.355 1.00 79.45  ? 410 VAL A CA  1 
ATOM   2664  C C   . VAL A 1 410 ? 115.617 103.439 164.687 1.00 83.70  ? 410 VAL A C   1 
ATOM   2665  O O   . VAL A 1 410 ? 116.149 102.998 165.697 1.00 88.03  ? 410 VAL A O   1 
ATOM   2666  C CB  . VAL A 1 410 ? 114.192 101.668 163.616 1.00 76.40  ? 410 VAL A CB  1 
ATOM   2667  C CG1 . VAL A 1 410 ? 115.070 100.592 164.259 1.00 80.44  ? 410 VAL A CG1 1 
ATOM   2668  C CG2 . VAL A 1 410 ? 112.781 101.086 163.542 1.00 74.72  ? 410 VAL A CG2 1 
ATOM   2669  N N   . ALA A 1 411 ? 116.272 104.273 163.872 1.00 80.78  ? 411 ALA A N   1 
ATOM   2670  C CA  . ALA A 1 411 ? 117.582 104.844 164.189 1.00 78.05  ? 411 ALA A CA  1 
ATOM   2671  C C   . ALA A 1 411 ? 117.466 106.027 165.170 1.00 86.76  ? 411 ALA A C   1 
ATOM   2672  O O   . ALA A 1 411 ? 118.174 106.089 166.177 1.00 90.52  ? 411 ALA A O   1 
ATOM   2673  C CB  . ALA A 1 411 ? 118.269 105.234 162.882 1.00 72.12  ? 411 ALA A CB  1 
ATOM   2674  N N   . TYR A 1 412 ? 116.513 106.931 164.939 1.00 88.66  ? 412 TYR A N   1 
ATOM   2675  C CA  . TYR A 1 412 ? 115.896 107.697 166.017 1.00 84.02  ? 412 TYR A CA  1 
ATOM   2676  C C   . TYR A 1 412 ? 115.114 106.706 166.912 1.00 90.25  ? 412 TYR A C   1 
ATOM   2677  O O   . TYR A 1 412 ? 114.787 105.610 166.473 1.00 93.36  ? 412 TYR A O   1 
ATOM   2678  C CB  . TYR A 1 412 ? 115.022 108.789 165.379 1.00 84.90  ? 412 TYR A CB  1 
ATOM   2679  C CG  . TYR A 1 412 ? 114.686 109.975 166.260 1.00 92.19  ? 412 TYR A CG  1 
ATOM   2680  C CD1 . TYR A 1 412 ? 113.575 109.921 167.111 1.00 93.54  ? 412 TYR A CD1 1 
ATOM   2681  C CD2 . TYR A 1 412 ? 115.443 111.156 166.181 1.00 91.17  ? 412 TYR A CD2 1 
ATOM   2682  C CE1 . TYR A 1 412 ? 113.214 111.035 167.886 1.00 92.13  ? 412 TYR A CE1 1 
ATOM   2683  C CE2 . TYR A 1 412 ? 115.082 112.281 166.948 1.00 89.83  ? 412 TYR A CE2 1 
ATOM   2684  C CZ  . TYR A 1 412 ? 113.957 112.224 167.795 1.00 93.93  ? 412 TYR A CZ  1 
ATOM   2685  O OH  . TYR A 1 412 ? 113.573 113.301 168.528 1.00 92.31  ? 412 TYR A OH  1 
ATOM   2686  N N   . HIS A 1 413 ? 114.827 107.016 168.173 1.00 97.67  ? 413 HIS A N   1 
ATOM   2687  C CA  . HIS A 1 413 ? 114.237 106.060 169.132 1.00 100.46 ? 413 HIS A CA  1 
ATOM   2688  C C   . HIS A 1 413 ? 115.064 104.785 169.432 1.00 100.85 ? 413 HIS A C   1 
ATOM   2689  O O   . HIS A 1 413 ? 114.527 103.839 170.007 1.00 102.82 ? 413 HIS A O   1 
ATOM   2690  C CB  . HIS A 1 413 ? 112.779 105.688 168.799 1.00 93.58  ? 413 HIS A CB  1 
ATOM   2691  C CG  . HIS A 1 413 ? 111.881 106.794 168.333 1.00 96.33  ? 413 HIS A CG  1 
ATOM   2692  N ND1 . HIS A 1 413 ? 111.374 106.911 167.065 1.00 98.91  ? 413 HIS A ND1 1 
ATOM   2693  C CD2 . HIS A 1 413 ? 111.303 107.774 169.088 1.00 99.33  ? 413 HIS A CD2 1 
ATOM   2694  C CE1 . HIS A 1 413 ? 110.508 107.933 167.043 1.00 100.32 ? 413 HIS A CE1 1 
ATOM   2695  N NE2 . HIS A 1 413 ? 110.434 108.499 168.259 1.00 100.91 ? 413 HIS A NE2 1 
ATOM   2696  N N   . GLN A 1 414 ? 116.371 104.744 169.139 1.00 99.43  ? 414 GLN A N   1 
ATOM   2697  C CA  . GLN A 1 414 ? 117.255 103.721 169.717 1.00 100.79 ? 414 GLN A CA  1 
ATOM   2698  C C   . GLN A 1 414 ? 117.314 103.857 171.252 1.00 109.94 ? 414 GLN A C   1 
ATOM   2699  O O   . GLN A 1 414 ? 117.307 104.983 171.764 1.00 107.66 ? 414 GLN A O   1 
ATOM   2700  C CB  . GLN A 1 414 ? 118.684 103.812 169.153 1.00 98.31  ? 414 GLN A CB  1 
ATOM   2701  C CG  . GLN A 1 414 ? 118.844 103.187 167.768 1.00 100.12 ? 414 GLN A CG  1 
ATOM   2702  C CD  . GLN A 1 414 ? 118.639 101.678 167.779 1.00 105.78 ? 414 GLN A CD  1 
ATOM   2703  O OE1 . GLN A 1 414 ? 119.420 100.922 168.331 1.00 107.67 ? 414 GLN A OE1 1 
ATOM   2704  N NE2 . GLN A 1 414 ? 117.589 101.189 167.178 1.00 104.06 ? 414 GLN A NE2 1 
ATOM   2705  N N   . PRO A 1 415 ? 117.408 102.747 172.005 1.00 121.57 ? 415 PRO A N   1 
ATOM   2706  C CA  . PRO A 1 415 ? 117.596 102.773 173.450 1.00 116.29 ? 415 PRO A CA  1 
ATOM   2707  C C   . PRO A 1 415 ? 119.027 103.186 173.831 1.00 116.14 ? 415 PRO A C   1 
ATOM   2708  O O   . PRO A 1 415 ? 119.937 103.175 173.000 1.00 112.02 ? 415 PRO A O   1 
ATOM   2709  C CB  . PRO A 1 415 ? 117.270 101.352 173.910 1.00 114.52 ? 415 PRO A CB  1 
ATOM   2710  C CG  . PRO A 1 415 ? 117.718 100.499 172.729 1.00 114.62 ? 415 PRO A CG  1 
ATOM   2711  C CD  . PRO A 1 415 ? 117.376 101.375 171.528 1.00 116.43 ? 415 PRO A CD  1 
ATOM   2712  N N   . SER A 1 416 ? 119.240 103.519 175.103 1.00 124.40 ? 416 SER A N   1 
ATOM   2713  C CA  . SER A 1 416 ? 120.573 103.783 175.661 1.00 126.27 ? 416 SER A CA  1 
ATOM   2714  C C   . SER A 1 416 ? 121.494 102.561 175.545 1.00 125.42 ? 416 SER A C   1 
ATOM   2715  O O   . SER A 1 416 ? 121.043 101.420 175.632 1.00 123.39 ? 416 SER A O   1 
ATOM   2716  C CB  . SER A 1 416 ? 120.472 104.203 177.127 1.00 125.23 ? 416 SER A CB  1 
ATOM   2717  O OG  . SER A 1 416 ? 119.575 105.290 177.267 1.00 122.52 ? 416 SER A OG  1 
ATOM   2718  N N   . LEU A 1 417 ? 122.794 102.783 175.363 1.00 125.30 ? 417 LEU A N   1 
ATOM   2719  C CA  . LEU A 1 417 ? 123.749 101.766 174.911 1.00 126.14 ? 417 LEU A CA  1 
ATOM   2720  C C   . LEU A 1 417 ? 125.087 101.932 175.636 1.00 123.13 ? 417 LEU A C   1 
ATOM   2721  O O   . LEU A 1 417 ? 125.754 100.946 175.967 1.00 120.08 ? 417 LEU A O   1 
ATOM   2722  C CB  . LEU A 1 417 ? 123.868 101.896 173.377 1.00 125.06 ? 417 LEU A CB  1 
ATOM   2723  C CG  . LEU A 1 417 ? 124.914 101.002 172.695 1.00 124.70 ? 417 LEU A CG  1 
ATOM   2724  C CD1 . LEU A 1 417 ? 124.570 99.529  172.867 1.00 122.84 ? 417 LEU A CD1 1 
ATOM   2725  C CD2 . LEU A 1 417 ? 124.974 101.344 171.207 1.00 120.43 ? 417 LEU A CD2 1 
ATOM   2726  N N   . PHE A 1 429 ? 104.396 98.440  174.559 1.00 127.92 ? 429 PHE A N   1 
ATOM   2727  C CA  . PHE A 1 429 ? 104.115 98.395  173.128 1.00 131.16 ? 429 PHE A CA  1 
ATOM   2728  C C   . PHE A 1 429 ? 105.257 98.997  172.296 1.00 132.75 ? 429 PHE A C   1 
ATOM   2729  O O   . PHE A 1 429 ? 105.624 98.461  171.251 1.00 130.26 ? 429 PHE A O   1 
ATOM   2730  C CB  . PHE A 1 429 ? 102.797 99.132  172.870 1.00 129.67 ? 429 PHE A CB  1 
ATOM   2731  C CG  . PHE A 1 429 ? 102.406 99.273  171.411 1.00 130.30 ? 429 PHE A CG  1 
ATOM   2732  C CD1 . PHE A 1 429 ? 101.958 98.156  170.690 1.00 129.80 ? 429 PHE A CD1 1 
ATOM   2733  C CD2 . PHE A 1 429 ? 102.459 100.529 170.783 1.00 131.03 ? 429 PHE A CD2 1 
ATOM   2734  C CE1 . PHE A 1 429 ? 101.563 98.295  169.350 1.00 130.68 ? 429 PHE A CE1 1 
ATOM   2735  C CE2 . PHE A 1 429 ? 102.055 100.668 169.445 1.00 131.18 ? 429 PHE A CE2 1 
ATOM   2736  C CZ  . PHE A 1 429 ? 101.605 99.554  168.728 1.00 131.08 ? 429 PHE A CZ  1 
ATOM   2737  N N   . GLY A 1 430 ? 105.880 100.074 172.776 1.00 130.45 ? 430 GLY A N   1 
ATOM   2738  C CA  . GLY A 1 430 ? 106.982 100.735 172.073 1.00 127.16 ? 430 GLY A CA  1 
ATOM   2739  C C   . GLY A 1 430 ? 108.194 99.822  171.850 1.00 129.67 ? 430 GLY A C   1 
ATOM   2740  O O   . GLY A 1 430 ? 108.819 99.880  170.794 1.00 131.89 ? 430 GLY A O   1 
ATOM   2741  N N   . GLU A 1 431 ? 108.499 98.930  172.791 1.00 126.26 ? 431 GLU A N   1 
ATOM   2742  C CA  . GLU A 1 431 ? 109.614 97.986  172.685 1.00 123.51 ? 431 GLU A CA  1 
ATOM   2743  C C   . GLU A 1 431 ? 109.371 96.861  171.669 1.00 126.03 ? 431 GLU A C   1 
ATOM   2744  O O   . GLU A 1 431 ? 110.287 96.497  170.931 1.00 125.58 ? 431 GLU A O   1 
ATOM   2745  C CB  . GLU A 1 431 ? 109.885 97.390  174.061 1.00 123.23 ? 431 GLU A CB  1 
ATOM   2746  N N   . SER A 1 432 ? 108.151 96.321  171.569 1.00 124.57 ? 432 SER A N   1 
ATOM   2747  C CA  . SER A 1 432 ? 107.829 95.308  170.552 1.00 124.71 ? 432 SER A CA  1 
ATOM   2748  C C   . SER A 1 432 ? 107.690 95.925  169.157 1.00 123.61 ? 432 SER A C   1 
ATOM   2749  O O   . SER A 1 432 ? 108.144 95.327  168.186 1.00 121.10 ? 432 SER A O   1 
ATOM   2750  C CB  . SER A 1 432 ? 106.585 94.504  170.930 1.00 124.59 ? 432 SER A CB  1 
ATOM   2751  O OG  . SER A 1 432 ? 105.433 95.313  170.978 1.00 126.04 ? 432 SER A OG  1 
ATOM   2752  N N   . MET A 1 433 ? 107.180 97.154  169.034 1.00 119.73 ? 433 MET A N   1 
ATOM   2753  C CA  . MET A 1 433 ? 107.220 97.903  167.771 1.00 117.77 ? 433 MET A CA  1 
ATOM   2754  C C   . MET A 1 433 ? 108.645 98.280  167.348 1.00 116.59 ? 433 MET A C   1 
ATOM   2755  O O   . MET A 1 433 ? 108.949 98.255  166.157 1.00 117.79 ? 433 MET A O   1 
ATOM   2756  C CB  . MET A 1 433 ? 106.347 99.158  167.860 1.00 118.17 ? 433 MET A CB  1 
ATOM   2757  C CG  . MET A 1 433 ? 104.858 98.812  167.946 1.00 122.27 ? 433 MET A CG  1 
ATOM   2758  S SD  . MET A 1 433 ? 104.177 97.878  166.546 1.00 128.14 ? 433 MET A SD  1 
ATOM   2759  C CE  . MET A 1 433 ? 104.277 99.132  165.249 1.00 118.10 ? 433 MET A CE  1 
ATOM   2760  N N   . LEU A 1 434 ? 109.554 98.569  168.281 1.00 111.55 ? 434 LEU A N   1 
ATOM   2761  C CA  . LEU A 1 434 ? 110.976 98.739  167.969 1.00 110.24 ? 434 LEU A CA  1 
ATOM   2762  C C   . LEU A 1 434 ? 111.593 97.431  167.459 1.00 112.54 ? 434 LEU A C   1 
ATOM   2763  O O   . LEU A 1 434 ? 112.305 97.448  166.457 1.00 115.42 ? 434 LEU A O   1 
ATOM   2764  C CB  . LEU A 1 434 ? 111.723 99.285  169.198 1.00 110.04 ? 434 LEU A CB  1 
ATOM   2765  C CG  . LEU A 1 434 ? 113.243 99.411  169.004 1.00 111.05 ? 434 LEU A CG  1 
ATOM   2766  C CD1 . LEU A 1 434 ? 113.596 100.455 167.951 1.00 110.75 ? 434 LEU A CD1 1 
ATOM   2767  C CD2 . LEU A 1 434 ? 113.915 99.800  170.314 1.00 112.38 ? 434 LEU A CD2 1 
ATOM   2768  N N   . LEU A 1 435 ? 111.307 96.288  168.094 1.00 110.77 ? 435 LEU A N   1 
ATOM   2769  C CA  . LEU A 1 435 ? 111.782 94.989  167.604 1.00 111.60 ? 435 LEU A CA  1 
ATOM   2770  C C   . LEU A 1 435 ? 111.245 94.670  166.198 1.00 108.60 ? 435 LEU A C   1 
ATOM   2771  O O   . LEU A 1 435 ? 112.018 94.273  165.329 1.00 106.05 ? 435 LEU A O   1 
ATOM   2772  C CB  . LEU A 1 435 ? 111.414 93.896  168.623 1.00 113.83 ? 435 LEU A CB  1 
ATOM   2773  C CG  . LEU A 1 435 ? 111.846 92.474  168.221 1.00 113.99 ? 435 LEU A CG  1 
ATOM   2774  C CD1 . LEU A 1 435 ? 113.361 92.359  168.053 1.00 109.57 ? 435 LEU A CD1 1 
ATOM   2775  C CD2 . LEU A 1 435 ? 111.400 91.496  169.304 1.00 109.92 ? 435 LEU A CD2 1 
ATOM   2776  N N   . LEU A 1 436 ? 109.952 94.901  165.939 1.00 101.39 ? 436 LEU A N   1 
ATOM   2777  C CA  . LEU A 1 436 ? 109.367 94.778  164.602 1.00 101.16 ? 436 LEU A CA  1 
ATOM   2778  C C   . LEU A 1 436 ? 110.113 95.661  163.596 1.00 105.16 ? 436 LEU A C   1 
ATOM   2779  O O   . LEU A 1 436 ? 110.493 95.184  162.534 1.00 106.75 ? 436 LEU A O   1 
ATOM   2780  C CB  . LEU A 1 436 ? 107.872 95.137  164.672 1.00 101.15 ? 436 LEU A CB  1 
ATOM   2781  C CG  . LEU A 1 436 ? 107.162 95.198  163.309 1.00 99.96  ? 436 LEU A CG  1 
ATOM   2782  C CD1 . LEU A 1 436 ? 107.138 93.838  162.621 1.00 102.06 ? 436 LEU A CD1 1 
ATOM   2783  C CD2 . LEU A 1 436 ? 105.731 95.670  163.500 1.00 98.01  ? 436 LEU A CD2 1 
ATOM   2784  N N   . GLY A 1 437 ? 110.385 96.919  163.943 1.00 97.04  ? 437 GLY A N   1 
ATOM   2785  C CA  . GLY A 1 437 ? 111.155 97.832  163.106 1.00 89.54  ? 437 GLY A CA  1 
ATOM   2786  C C   . GLY A 1 437 ? 112.540 97.289  162.753 1.00 92.60  ? 437 GLY A C   1 
ATOM   2787  O O   . GLY A 1 437 ? 112.930 97.334  161.590 1.00 102.82 ? 437 GLY A O   1 
ATOM   2788  N N   . HIS A 1 438 ? 113.264 96.704  163.706 1.00 92.79  ? 438 HIS A N   1 
ATOM   2789  C CA  . HIS A 1 438 ? 114.549 96.052  163.432 1.00 91.74  ? 438 HIS A CA  1 
ATOM   2790  C C   . HIS A 1 438 ? 114.427 94.851  162.489 1.00 97.22  ? 438 HIS A C   1 
ATOM   2791  O O   . HIS A 1 438 ? 115.264 94.689  161.604 1.00 99.10  ? 438 HIS A O   1 
ATOM   2792  C CB  . HIS A 1 438 ? 115.211 95.630  164.747 1.00 96.29  ? 438 HIS A CB  1 
ATOM   2793  C CG  . HIS A 1 438 ? 116.009 96.739  165.364 1.00 99.01  ? 438 HIS A CG  1 
ATOM   2794  N ND1 . HIS A 1 438 ? 117.222 97.192  164.909 1.00 100.22 ? 438 HIS A ND1 1 
ATOM   2795  C CD2 . HIS A 1 438 ? 115.650 97.529  166.417 1.00 97.99  ? 438 HIS A CD2 1 
ATOM   2796  C CE1 . HIS A 1 438 ? 117.598 98.222  165.681 1.00 97.76  ? 438 HIS A CE1 1 
ATOM   2797  N NE2 . HIS A 1 438 ? 116.674 98.457  166.623 1.00 98.42  ? 438 HIS A NE2 1 
ATOM   2798  N N   . ILE A 1 439 ? 113.390 94.023  162.625 1.00 102.72 ? 439 ILE A N   1 
ATOM   2799  C CA  . ILE A 1 439 ? 113.158 92.896  161.712 1.00 98.95  ? 439 ILE A CA  1 
ATOM   2800  C C   . ILE A 1 439 ? 112.781 93.387  160.308 1.00 95.88  ? 439 ILE A C   1 
ATOM   2801  O O   . ILE A 1 439 ? 113.343 92.903  159.331 1.00 98.40  ? 439 ILE A O   1 
ATOM   2802  C CB  . ILE A 1 439 ? 112.124 91.916  162.303 1.00 98.32  ? 439 ILE A CB  1 
ATOM   2803  C CG1 . ILE A 1 439 ? 112.623 91.263  163.610 1.00 99.75  ? 439 ILE A CG1 1 
ATOM   2804  C CG2 . ILE A 1 439 ? 111.737 90.825  161.299 1.00 94.53  ? 439 ILE A CG2 1 
ATOM   2805  C CD1 . ILE A 1 439 ? 113.938 90.497  163.529 1.00 95.58  ? 439 ILE A CD1 1 
ATOM   2806  N N   . LEU A 1 440 ? 111.912 94.388  160.168 1.00 84.91  ? 440 LEU A N   1 
ATOM   2807  C CA  . LEU A 1 440 ? 111.622 94.989  158.867 1.00 86.53  ? 440 LEU A CA  1 
ATOM   2808  C C   . LEU A 1 440 ? 112.865 95.605  158.212 1.00 87.07  ? 440 LEU A C   1 
ATOM   2809  O O   . LEU A 1 440 ? 113.043 95.465  157.009 1.00 93.38  ? 440 LEU A O   1 
ATOM   2810  C CB  . LEU A 1 440 ? 110.500 96.029  159.012 1.00 88.65  ? 440 LEU A CB  1 
ATOM   2811  C CG  . LEU A 1 440 ? 109.139 95.446  159.421 1.00 92.38  ? 440 LEU A CG  1 
ATOM   2812  C CD1 . LEU A 1 440 ? 108.146 96.581  159.647 1.00 89.27  ? 440 LEU A CD1 1 
ATOM   2813  C CD2 . LEU A 1 440 ? 108.566 94.520  158.357 1.00 90.98  ? 440 LEU A CD2 1 
ATOM   2814  N N   . ILE A 1 441 ? 113.766 96.229  158.973 1.00 77.31  ? 441 ILE A N   1 
ATOM   2815  C CA  . ILE A 1 441 ? 115.046 96.732  158.451 1.00 79.97  ? 441 ILE A CA  1 
ATOM   2816  C C   . ILE A 1 441 ? 115.977 95.588  158.051 1.00 85.35  ? 441 ILE A C   1 
ATOM   2817  O O   . ILE A 1 441 ? 116.610 95.679  157.006 1.00 92.07  ? 441 ILE A O   1 
ATOM   2818  C CB  . ILE A 1 441 ? 115.707 97.679  159.467 1.00 84.82  ? 441 ILE A CB  1 
ATOM   2819  C CG1 . ILE A 1 441 ? 114.903 98.986  159.520 1.00 84.98  ? 441 ILE A CG1 1 
ATOM   2820  C CG2 . ILE A 1 441 ? 117.169 98.004  159.135 1.00 85.37  ? 441 ILE A CG2 1 
ATOM   2821  C CD1 . ILE A 1 441 ? 115.189 99.779  160.787 1.00 90.96  ? 441 ILE A CD1 1 
ATOM   2822  N N   . LEU A 1 442 ? 116.051 94.496  158.814 1.00 78.79  ? 442 LEU A N   1 
ATOM   2823  C CA  . LEU A 1 442 ? 116.822 93.310  158.430 1.00 77.73  ? 442 LEU A CA  1 
ATOM   2824  C C   . LEU A 1 442 ? 116.302 92.721  157.111 1.00 82.34  ? 442 LEU A C   1 
ATOM   2825  O O   . LEU A 1 442 ? 117.082 92.481  156.198 1.00 82.72  ? 442 LEU A O   1 
ATOM   2826  C CB  . LEU A 1 442 ? 116.766 92.276  159.568 1.00 81.79  ? 442 LEU A CB  1 
ATOM   2827  C CG  . LEU A 1 442 ? 117.504 90.962  159.262 1.00 83.38  ? 442 LEU A CG  1 
ATOM   2828  C CD1 . LEU A 1 442 ? 119.010 91.149  159.215 1.00 79.60  ? 442 LEU A CD1 1 
ATOM   2829  C CD2 . LEU A 1 442 ? 117.174 89.931  160.330 1.00 80.70  ? 442 LEU A CD2 1 
ATOM   2830  N N   . LEU A 1 443 ? 114.990 92.520  156.984 1.00 88.96  ? 443 LEU A N   1 
ATOM   2831  C CA  . LEU A 1 443 ? 114.370 91.973  155.778 1.00 81.90  ? 443 LEU A CA  1 
ATOM   2832  C C   . LEU A 1 443 ? 114.496 92.909  154.573 1.00 80.39  ? 443 LEU A C   1 
ATOM   2833  O O   . LEU A 1 443 ? 114.852 92.448  153.497 1.00 87.10  ? 443 LEU A O   1 
ATOM   2834  C CB  . LEU A 1 443 ? 112.897 91.636  156.045 1.00 81.91  ? 443 LEU A CB  1 
ATOM   2835  C CG  . LEU A 1 443 ? 112.665 90.497  157.049 1.00 86.02  ? 443 LEU A CG  1 
ATOM   2836  C CD1 . LEU A 1 443 ? 111.164 90.286  157.207 1.00 84.20  ? 443 LEU A CD1 1 
ATOM   2837  C CD2 . LEU A 1 443 ? 113.296 89.177  156.611 1.00 83.01  ? 443 LEU A CD2 1 
ATOM   2838  N N   . GLY A 1 444 ? 114.291 94.218  154.731 1.00 69.94  ? 444 GLY A N   1 
ATOM   2839  C CA  . GLY A 1 444 ? 114.560 95.196  153.675 1.00 72.89  ? 444 GLY A CA  1 
ATOM   2840  C C   . GLY A 1 444 ? 116.039 95.268  153.284 1.00 73.53  ? 444 GLY A C   1 
ATOM   2841  O O   . GLY A 1 444 ? 116.360 95.405  152.109 1.00 81.71  ? 444 GLY A O   1 
ATOM   2842  N N   . GLY A 1 445 ? 116.956 95.091  154.236 1.00 71.25  ? 445 GLY A N   1 
ATOM   2843  C CA  . GLY A 1 445 ? 118.391 95.038  153.982 1.00 68.09  ? 445 GLY A CA  1 
ATOM   2844  C C   . GLY A 1 445 ? 118.828 93.766  153.268 1.00 71.66  ? 445 GLY A C   1 
ATOM   2845  O O   . GLY A 1 445 ? 119.583 93.848  152.310 1.00 82.65  ? 445 GLY A O   1 
ATOM   2846  N N   . ILE A 1 446 ? 118.300 92.596  153.634 1.00 74.69  ? 446 ILE A N   1 
ATOM   2847  C CA  . ILE A 1 446 ? 118.527 91.343  152.901 1.00 71.63  ? 446 ILE A CA  1 
ATOM   2848  C C   . ILE A 1 446 ? 117.895 91.409  151.508 1.00 78.33  ? 446 ILE A C   1 
ATOM   2849  O O   . ILE A 1 446 ? 118.547 91.042  150.539 1.00 82.97  ? 446 ILE A O   1 
ATOM   2850  C CB  . ILE A 1 446 ? 118.005 90.135  153.708 1.00 75.36  ? 446 ILE A CB  1 
ATOM   2851  C CG1 . ILE A 1 446 ? 118.901 89.902  154.941 1.00 80.31  ? 446 ILE A CG1 1 
ATOM   2852  C CG2 . ILE A 1 446 ? 117.951 88.855  152.856 1.00 74.32  ? 446 ILE A CG2 1 
ATOM   2853  C CD1 . ILE A 1 446 ? 118.325 88.896  155.943 1.00 77.39  ? 446 ILE A CD1 1 
ATOM   2854  N N   . TYR A 1 447 ? 116.668 91.914  151.367 1.00 76.24  ? 447 TYR A N   1 
ATOM   2855  C CA  . TYR A 1 447 ? 116.025 92.069  150.064 1.00 66.08  ? 447 TYR A CA  1 
ATOM   2856  C C   . TYR A 1 447 ? 116.863 92.921  149.111 1.00 71.03  ? 447 TYR A C   1 
ATOM   2857  O O   . TYR A 1 447 ? 117.136 92.500  147.992 1.00 82.24  ? 447 TYR A O   1 
ATOM   2858  C CB  . TYR A 1 447 ? 114.628 92.670  150.241 1.00 68.44  ? 447 TYR A CB  1 
ATOM   2859  C CG  . TYR A 1 447 ? 113.906 92.850  148.927 1.00 76.93  ? 447 TYR A CG  1 
ATOM   2860  C CD1 . TYR A 1 447 ? 114.144 93.990  148.138 1.00 78.63  ? 447 TYR A CD1 1 
ATOM   2861  C CD2 . TYR A 1 447 ? 113.066 91.831  148.452 1.00 76.57  ? 447 TYR A CD2 1 
ATOM   2862  C CE1 . TYR A 1 447 ? 113.598 94.087  146.846 1.00 72.39  ? 447 TYR A CE1 1 
ATOM   2863  C CE2 . TYR A 1 447 ? 112.504 91.932  147.172 1.00 79.34  ? 447 TYR A CE2 1 
ATOM   2864  C CZ  . TYR A 1 447 ? 112.792 93.043  146.354 1.00 79.94  ? 447 TYR A CZ  1 
ATOM   2865  O OH  . TYR A 1 447 ? 112.314 93.098  145.087 1.00 86.69  ? 447 TYR A OH  1 
ATOM   2866  N N   . LEU A 1 448 ? 117.312 94.102  149.547 1.00 65.29  ? 448 LEU A N   1 
ATOM   2867  C CA  . LEU A 1 448 ? 118.181 94.963  148.751 1.00 60.17  ? 448 LEU A CA  1 
ATOM   2868  C C   . LEU A 1 448 ? 119.564 94.344  148.527 1.00 65.26  ? 448 LEU A C   1 
ATOM   2869  O O   . LEU A 1 448 ? 120.095 94.484  147.430 1.00 78.23  ? 448 LEU A O   1 
ATOM   2870  C CB  . LEU A 1 448 ? 118.307 96.335  149.426 1.00 70.71  ? 448 LEU A CB  1 
ATOM   2871  C CG  . LEU A 1 448 ? 117.026 97.182  149.394 1.00 67.39  ? 448 LEU A CG  1 
ATOM   2872  C CD1 . LEU A 1 448 ? 117.193 98.375  150.322 1.00 70.87  ? 448 LEU A CD1 1 
ATOM   2873  C CD2 . LEU A 1 448 ? 116.738 97.722  147.997 1.00 70.72  ? 448 LEU A CD2 1 
ATOM   2874  N N   . LEU A 1 449 ? 120.140 93.626  149.499 1.00 68.74  ? 449 LEU A N   1 
ATOM   2875  C CA  . LEU A 1 449 ? 121.411 92.926  149.296 1.00 67.55  ? 449 LEU A CA  1 
ATOM   2876  C C   . LEU A 1 449 ? 121.269 91.867  148.208 1.00 74.26  ? 449 LEU A C   1 
ATOM   2877  O O   . LEU A 1 449 ? 122.072 91.834  147.277 1.00 75.08  ? 449 LEU A O   1 
ATOM   2878  C CB  . LEU A 1 449 ? 121.890 92.320  150.626 1.00 71.52  ? 449 LEU A CB  1 
ATOM   2879  C CG  . LEU A 1 449 ? 123.183 91.502  150.539 1.00 74.06  ? 449 LEU A CG  1 
ATOM   2880  C CD1 . LEU A 1 449 ? 124.333 92.328  149.992 1.00 74.40  ? 449 LEU A CD1 1 
ATOM   2881  C CD2 . LEU A 1 449 ? 123.575 91.016  151.925 1.00 72.98  ? 449 LEU A CD2 1 
ATOM   2882  N N   . LEU A 1 450 ? 120.219 91.038  148.213 1.00 79.71  ? 450 LEU A N   1 
ATOM   2883  C CA  . LEU A 1 450 ? 119.967 90.046  147.158 1.00 74.41  ? 450 LEU A CA  1 
ATOM   2884  C C   . LEU A 1 450 ? 119.657 90.678  145.794 1.00 74.77  ? 450 LEU A C   1 
ATOM   2885  O O   . LEU A 1 450 ? 120.189 90.236  144.782 1.00 78.02  ? 450 LEU A O   1 
ATOM   2886  C CB  . LEU A 1 450 ? 118.821 89.113  147.573 1.00 73.59  ? 450 LEU A CB  1 
ATOM   2887  C CG  . LEU A 1 450 ? 119.143 88.192  148.753 1.00 76.25  ? 450 LEU A CG  1 
ATOM   2888  C CD1 . LEU A 1 450 ? 117.915 87.352  149.076 1.00 74.01  ? 450 LEU A CD1 1 
ATOM   2889  C CD2 . LEU A 1 450 ? 120.304 87.248  148.459 1.00 72.64  ? 450 LEU A CD2 1 
ATOM   2890  N N   . GLY A 1 451 ? 118.849 91.735  145.748 1.00 77.34  ? 451 GLY A N   1 
ATOM   2891  C CA  . GLY A 1 451 ? 118.557 92.464  144.516 1.00 69.98  ? 451 GLY A CA  1 
ATOM   2892  C C   . GLY A 1 451 ? 119.794 93.076  143.854 1.00 70.93  ? 451 GLY A C   1 
ATOM   2893  O O   . GLY A 1 451 ? 119.932 92.990  142.634 1.00 78.23  ? 451 GLY A O   1 
ATOM   2894  N N   . GLN A 1 452 ? 120.733 93.643  144.618 1.00 73.99  ? 452 GLN A N   1 
ATOM   2895  C CA  . GLN A 1 452 ? 121.972 94.179  144.047 1.00 74.64  ? 452 GLN A CA  1 
ATOM   2896  C C   . GLN A 1 452 ? 123.018 93.107  143.724 1.00 71.10  ? 452 GLN A C   1 
ATOM   2897  O O   . GLN A 1 452 ? 123.731 93.242  142.734 1.00 80.57  ? 452 GLN A O   1 
ATOM   2898  C CB  . GLN A 1 452 ? 122.578 95.239  144.970 1.00 71.00  ? 452 GLN A CB  1 
ATOM   2899  C CG  . GLN A 1 452 ? 121.707 96.487  145.135 1.00 68.84  ? 452 GLN A CG  1 
ATOM   2900  C CD  . GLN A 1 452 ? 121.317 97.151  143.823 1.00 75.09  ? 452 GLN A CD  1 
ATOM   2901  O OE1 . GLN A 1 452 ? 120.151 97.256  143.485 1.00 80.89  ? 452 GLN A OE1 1 
ATOM   2902  N NE2 . GLN A 1 452 ? 122.248 97.611  143.024 1.00 71.97  ? 452 GLN A NE2 1 
ATOM   2903  N N   . LEU A 1 453 ? 123.108 92.015  144.484 1.00 68.67  ? 453 LEU A N   1 
ATOM   2904  C CA  . LEU A 1 453 ? 123.958 90.889  144.083 1.00 73.51  ? 453 LEU A CA  1 
ATOM   2905  C C   . LEU A 1 453 ? 123.442 90.232  142.794 1.00 75.71  ? 453 LEU A C   1 
ATOM   2906  O O   . LEU A 1 453 ? 124.245 89.864  141.943 1.00 80.49  ? 453 LEU A O   1 
ATOM   2907  C CB  . LEU A 1 453 ? 124.075 89.871  145.225 1.00 77.27  ? 453 LEU A CB  1 
ATOM   2908  C CG  . LEU A 1 453 ? 124.908 90.357  146.426 1.00 78.39  ? 453 LEU A CG  1 
ATOM   2909  C CD1 . LEU A 1 453 ? 124.800 89.343  147.554 1.00 71.75  ? 453 LEU A CD1 1 
ATOM   2910  C CD2 . LEU A 1 453 ? 126.383 90.511  146.085 1.00 73.75  ? 453 LEU A CD2 1 
ATOM   2911  N N   . TRP A 1 454 ? 122.126 90.157  142.579 1.00 86.82  ? 454 TRP A N   1 
ATOM   2912  C CA  . TRP A 1 454 ? 121.561 89.727  141.298 1.00 81.58  ? 454 TRP A CA  1 
ATOM   2913  C C   . TRP A 1 454 ? 121.914 90.685  140.154 1.00 81.50  ? 454 TRP A C   1 
ATOM   2914  O O   . TRP A 1 454 ? 122.319 90.221  139.096 1.00 92.75  ? 454 TRP A O   1 
ATOM   2915  C CB  . TRP A 1 454 ? 120.049 89.553  141.430 1.00 82.21  ? 454 TRP A CB  1 
ATOM   2916  C CG  . TRP A 1 454 ? 119.354 88.956  140.246 1.00 88.16  ? 454 TRP A CG  1 
ATOM   2917  C CD1 . TRP A 1 454 ? 119.626 87.746  139.711 1.00 88.62  ? 454 TRP A CD1 1 
ATOM   2918  C CD2 . TRP A 1 454 ? 118.241 89.491  139.467 1.00 92.71  ? 454 TRP A CD2 1 
ATOM   2919  N NE1 . TRP A 1 454 ? 118.765 87.496  138.663 1.00 86.52  ? 454 TRP A NE1 1 
ATOM   2920  C CE2 . TRP A 1 454 ? 117.867 88.522  138.492 1.00 89.18  ? 454 TRP A CE2 1 
ATOM   2921  C CE3 . TRP A 1 454 ? 117.491 90.687  139.498 1.00 90.47  ? 454 TRP A CE3 1 
ATOM   2922  C CZ2 . TRP A 1 454 ? 116.795 88.715  137.611 1.00 88.34  ? 454 TRP A CZ2 1 
ATOM   2923  C CZ3 . TRP A 1 454 ? 116.419 90.896  138.607 1.00 89.71  ? 454 TRP A CZ3 1 
ATOM   2924  C CH2 . TRP A 1 454 ? 116.062 89.910  137.673 1.00 91.21  ? 454 TRP A CH2 1 
ATOM   2925  N N   . TYR A 1 455 ? 121.862 92.006  140.357 1.00 75.95  ? 455 TYR A N   1 
ATOM   2926  C CA  . TYR A 1 455 ? 122.315 92.981  139.356 1.00 73.95  ? 455 TYR A CA  1 
ATOM   2927  C C   . TYR A 1 455 ? 123.768 92.752  138.941 1.00 81.50  ? 455 TYR A C   1 
ATOM   2928  O O   . TYR A 1 455 ? 124.051 92.575  137.758 1.00 90.87  ? 455 TYR A O   1 
ATOM   2929  C CB  . TYR A 1 455 ? 122.116 94.414  139.858 1.00 78.80  ? 455 TYR A CB  1 
ATOM   2930  C CG  . TYR A 1 455 ? 122.599 95.472  138.886 1.00 83.25  ? 455 TYR A CG  1 
ATOM   2931  C CD1 . TYR A 1 455 ? 121.780 95.853  137.813 1.00 83.54  ? 455 TYR A CD1 1 
ATOM   2932  C CD2 . TYR A 1 455 ? 123.870 96.056  139.028 1.00 83.11  ? 455 TYR A CD2 1 
ATOM   2933  C CE1 . TYR A 1 455 ? 122.221 96.811  136.885 1.00 82.29  ? 455 TYR A CE1 1 
ATOM   2934  C CE2 . TYR A 1 455 ? 124.324 97.007  138.096 1.00 88.26  ? 455 TYR A CE2 1 
ATOM   2935  C CZ  . TYR A 1 455 ? 123.494 97.391  137.022 1.00 89.72  ? 455 TYR A CZ  1 
ATOM   2936  O OH  . TYR A 1 455 ? 123.902 98.317  136.120 1.00 88.48  ? 455 TYR A OH  1 
ATOM   2937  N N   . PHE A 1 456 ? 124.707 92.679  139.884 1.00 84.30  ? 456 PHE A N   1 
ATOM   2938  C CA  . PHE A 1 456 ? 126.112 92.446  139.547 1.00 82.51  ? 456 PHE A CA  1 
ATOM   2939  C C   . PHE A 1 456 ? 126.398 91.033  139.037 1.00 86.95  ? 456 PHE A C   1 
ATOM   2940  O O   . PHE A 1 456 ? 127.324 90.861  138.255 1.00 93.64  ? 456 PHE A O   1 
ATOM   2941  C CB  . PHE A 1 456 ? 127.002 92.812  140.729 1.00 77.34  ? 456 PHE A CB  1 
ATOM   2942  C CG  . PHE A 1 456 ? 126.994 94.297  141.025 1.00 83.67  ? 456 PHE A CG  1 
ATOM   2943  C CD1 . PHE A 1 456 ? 127.448 95.201  140.049 1.00 85.47  ? 456 PHE A CD1 1 
ATOM   2944  C CD2 . PHE A 1 456 ? 126.511 94.778  142.250 1.00 80.73  ? 456 PHE A CD2 1 
ATOM   2945  C CE1 . PHE A 1 456 ? 127.424 96.581  140.297 1.00 85.99  ? 456 PHE A CE1 1 
ATOM   2946  C CE2 . PHE A 1 456 ? 126.486 96.158  142.499 1.00 80.57  ? 456 PHE A CE2 1 
ATOM   2947  C CZ  . PHE A 1 456 ? 126.950 97.055  141.527 1.00 85.08  ? 456 PHE A CZ  1 
ATOM   2948  N N   . TRP A 1 457 ? 125.592 90.030  139.381 1.00 88.82  ? 457 TRP A N   1 
ATOM   2949  C CA  . TRP A 1 457 ? 125.673 88.713  138.749 1.00 85.95  ? 457 TRP A CA  1 
ATOM   2950  C C   . TRP A 1 457 ? 125.241 88.750  137.279 1.00 90.31  ? 457 TRP A C   1 
ATOM   2951  O O   . TRP A 1 457 ? 125.949 88.231  136.419 1.00 92.35  ? 457 TRP A O   1 
ATOM   2952  C CB  . TRP A 1 457 ? 124.835 87.703  139.531 1.00 87.83  ? 457 TRP A CB  1 
ATOM   2953  C CG  . TRP A 1 457 ? 124.758 86.360  138.888 1.00 92.15  ? 457 TRP A CG  1 
ATOM   2954  C CD1 . TRP A 1 457 ? 123.649 85.800  138.359 1.00 91.96  ? 457 TRP A CD1 1 
ATOM   2955  C CD2 . TRP A 1 457 ? 125.837 85.408  138.655 1.00 95.33  ? 457 TRP A CD2 1 
ATOM   2956  N NE1 . TRP A 1 457 ? 123.967 84.577  137.810 1.00 94.31  ? 457 TRP A NE1 1 
ATOM   2957  C CE2 . TRP A 1 457 ? 125.307 84.290  137.953 1.00 95.48  ? 457 TRP A CE2 1 
ATOM   2958  C CE3 . TRP A 1 457 ? 127.215 85.383  138.958 1.00 93.13  ? 457 TRP A CE3 1 
ATOM   2959  C CZ2 . TRP A 1 457 ? 126.106 83.210  137.555 1.00 93.18  ? 457 TRP A CZ2 1 
ATOM   2960  C CZ3 . TRP A 1 457 ? 128.023 84.304  138.564 1.00 92.66  ? 457 TRP A CZ3 1 
ATOM   2961  C CH2 . TRP A 1 457 ? 127.475 83.222  137.859 1.00 93.28  ? 457 TRP A CH2 1 
ATOM   2962  N N   . ARG A 1 458 ? 124.141 89.449  136.977 1.00 84.24  ? 458 ARG A N   1 
ATOM   2963  C CA  . ARG A 1 458 ? 123.654 89.568  135.570 1.00 83.51  ? 458 ARG A CA  1 
ATOM   2964  C C   . ARG A 1 458 ? 124.628 90.392  134.725 1.00 87.63  ? 458 ARG A C   1 
ATOM   2965  O O   . ARG A 1 458 ? 124.817 90.046  133.544 1.00 88.55  ? 458 ARG A O   1 
ATOM   2966  C CB  . ARG A 1 458 ? 122.262 90.212  135.550 1.00 80.25  ? 458 ARG A CB  1 
ATOM   2967  C CG  . ARG A 1 458 ? 121.172 89.216  135.954 1.00 78.39  ? 458 ARG A CG  1 
ATOM   2968  C CD  . ARG A 1 458 ? 119.774 89.744  135.631 1.00 81.57  ? 458 ARG A CD  1 
ATOM   2969  N NE  . ARG A 1 458 ? 119.326 90.783  136.574 1.00 86.68  ? 458 ARG A NE  1 
ATOM   2970  C CZ  . ARG A 1 458 ? 119.598 92.078  136.458 1.00 85.29  ? 458 ARG A CZ  1 
ATOM   2971  N NH1 . ARG A 1 458 ? 119.149 92.931  137.363 1.00 83.47  ? 458 ARG A NH1 1 
ATOM   2972  N NH2 . ARG A 1 458 ? 120.319 92.516  135.441 1.00 82.90  ? 458 ARG A NH2 1 
ATOM   2973  N N   . ARG A 1 459 ? 125.215 91.430  135.304 1.00 87.39  ? 459 ARG A N   1 
ATOM   2974  C CA  . ARG A 1 459 ? 126.146 92.364  134.644 1.00 91.00  ? 459 ARG A CA  1 
ATOM   2975  C C   . ARG A 1 459 ? 127.629 91.957  134.695 1.00 97.61  ? 459 ARG A C   1 
ATOM   2976  O O   . ARG A 1 459 ? 128.485 92.703  134.233 1.00 99.31  ? 459 ARG A O   1 
ATOM   2977  C CB  . ARG A 1 459 ? 125.888 93.774  135.202 1.00 89.14  ? 459 ARG A CB  1 
ATOM   2978  C CG  . ARG A 1 459 ? 124.445 94.285  134.994 1.00 89.40  ? 459 ARG A CG  1 
ATOM   2979  C CD  . ARG A 1 459 ? 124.022 94.408  133.527 1.00 87.51  ? 459 ARG A CD  1 
ATOM   2980  N NE  . ARG A 1 459 ? 122.560 94.538  133.387 1.00 91.41  ? 459 ARG A NE  1 
ATOM   2981  C CZ  . ARG A 1 459 ? 121.820 94.083  132.391 1.00 96.08  ? 459 ARG A CZ  1 
ATOM   2982  N NH1 . ARG A 1 459 ? 120.536 94.263  132.405 1.00 89.26  ? 459 ARG A NH1 1 
ATOM   2983  N NH2 . ARG A 1 459 ? 122.325 93.436  131.381 1.00 93.80  ? 459 ARG A NH2 1 
ATOM   2984  N N   . ARG A 1 460 ? 127.903 90.755  135.236 1.00 106.31 ? 460 ARG A N   1 
ATOM   2985  C CA  . ARG A 1 460 ? 129.276 90.191  135.462 1.00 104.45 ? 460 ARG A CA  1 
ATOM   2986  C C   . ARG A 1 460 ? 130.276 90.427  134.323 1.00 105.98 ? 460 ARG A C   1 
ATOM   2987  O O   . ARG A 1 460 ? 131.401 90.868  134.629 1.00 105.26 ? 460 ARG A O   1 
ATOM   2988  C CB  . ARG A 1 460 ? 129.039 88.713  135.786 1.00 100.75 ? 460 ARG A CB  1 
ATOM   2989  C CG  . ARG A 1 460 ? 130.273 87.884  136.136 1.00 101.96 ? 460 ARG A CG  1 
ATOM   2990  C CD  . ARG A 1 460 ? 129.838 86.461  136.502 1.00 103.99 ? 460 ARG A CD  1 
ATOM   2991  N NE  . ARG A 1 460 ? 129.518 85.643  135.318 1.00 104.96 ? 460 ARG A NE  1 
ATOM   2992  C CZ  . ARG A 1 460 ? 128.291 85.462  134.843 1.00 103.30 ? 460 ARG A CZ  1 
ATOM   2993  N NH1 . ARG A 1 460 ? 128.099 84.710  133.773 1.00 101.34 ? 460 ARG A NH1 1 
ATOM   2994  N NH2 . ARG A 1 460 ? 127.259 86.028  135.444 1.00 100.69 ? 460 ARG A NH2 1 
ATOM   2995  N N   . LEU A 1 461 ? 129.903 90.159  133.077 1.00 103.82 ? 461 LEU A N   1 
ATOM   2996  C CA  . LEU A 1 461 ? 130.820 90.226  131.927 1.00 105.55 ? 461 LEU A CA  1 
ATOM   2997  C C   . LEU A 1 461 ? 131.282 91.655  131.584 1.00 105.51 ? 461 LEU A C   1 
ATOM   2998  O O   . LEU A 1 461 ? 132.328 91.831  130.960 1.00 100.63 ? 461 LEU A O   1 
ATOM   2999  C CB  . LEU A 1 461 ? 130.160 89.569  130.704 1.00 105.57 ? 461 LEU A CB  1 
ATOM   3000  C CG  . LEU A 1 461 ? 129.768 88.090  130.877 1.00 106.68 ? 461 LEU A CG  1 
ATOM   3001  C CD1 . LEU A 1 461 ? 129.189 87.561  129.572 1.00 102.12 ? 461 LEU A CD1 1 
ATOM   3002  C CD2 . LEU A 1 461 ? 130.946 87.203  131.261 1.00 106.34 ? 461 LEU A CD2 1 
ATOM   3003  N N   . PHE A 1 462 ? 130.501 92.664  131.966 1.00 105.49 ? 462 PHE A N   1 
ATOM   3004  C CA  . PHE A 1 462 ? 130.703 94.077  131.631 1.00 104.20 ? 462 PHE A CA  1 
ATOM   3005  C C   . PHE A 1 462 ? 130.524 94.932  132.890 1.00 102.01 ? 462 PHE A C   1 
ATOM   3006  O O   . PHE A 1 462 ? 129.859 95.971  132.883 1.00 102.33 ? 462 PHE A O   1 
ATOM   3007  C CB  . PHE A 1 462 ? 129.770 94.479  130.478 1.00 100.36 ? 462 PHE A CB  1 
ATOM   3008  C CG  . PHE A 1 462 ? 129.986 93.692  129.201 1.00 101.27 ? 462 PHE A CG  1 
ATOM   3009  C CD1 . PHE A 1 462 ? 131.049 94.019  128.343 1.00 99.05  ? 462 PHE A CD1 1 
ATOM   3010  C CD2 . PHE A 1 462 ? 129.166 92.591  128.901 1.00 103.01 ? 462 PHE A CD2 1 
ATOM   3011  C CE1 . PHE A 1 462 ? 131.305 93.238  127.205 1.00 100.28 ? 462 PHE A CE1 1 
ATOM   3012  C CE2 . PHE A 1 462 ? 129.422 91.806  127.766 1.00 105.40 ? 462 PHE A CE2 1 
ATOM   3013  C CZ  . PHE A 1 462 ? 130.498 92.126  126.923 1.00 102.49 ? 462 PHE A CZ  1 
ATOM   3014  N N   . ILE A 1 463 ? 131.060 94.450  134.008 1.00 106.69 ? 463 ILE A N   1 
ATOM   3015  C CA  . ILE A 1 463 ? 130.674 94.917  135.340 1.00 111.86 ? 463 ILE A CA  1 
ATOM   3016  C C   . ILE A 1 463 ? 131.044 96.388  135.569 1.00 114.75 ? 463 ILE A C   1 
ATOM   3017  O O   . ILE A 1 463 ? 130.202 97.158  136.020 1.00 112.69 ? 463 ILE A O   1 
ATOM   3018  C CB  . ILE A 1 463 ? 131.210 93.938  136.402 1.00 110.98 ? 463 ILE A CB  1 
ATOM   3019  C CG1 . ILE A 1 463 ? 130.536 94.200  137.758 1.00 110.93 ? 463 ILE A CG1 1 
ATOM   3020  C CG2 . ILE A 1 463 ? 132.740 93.964  136.525 1.00 110.68 ? 463 ILE A CG2 1 
ATOM   3021  C CD1 . ILE A 1 463 ? 130.812 93.123  138.803 1.00 109.15 ? 463 ILE A CD1 1 
ATOM   3022  N N   . TRP A 1 464 ? 132.232 96.820  135.134 1.00 113.54 ? 464 TRP A N   1 
ATOM   3023  C CA  . TRP A 1 464 ? 132.658 98.220  135.197 1.00 111.95 ? 464 TRP A CA  1 
ATOM   3024  C C   . TRP A 1 464 ? 131.796 99.139  134.328 1.00 112.02 ? 464 TRP A C   1 
ATOM   3025  O O   . TRP A 1 464 ? 131.375 100.209 134.765 1.00 112.46 ? 464 TRP A O   1 
ATOM   3026  C CB  . TRP A 1 464 ? 134.115 98.306  134.755 1.00 108.39 ? 464 TRP A CB  1 
ATOM   3027  N N   . ILE A 1 465 ? 131.438 98.703  133.118 1.00 106.82 ? 465 ILE A N   1 
ATOM   3028  C CA  . ILE A 1 465 ? 130.514 99.425  132.224 1.00 107.23 ? 465 ILE A CA  1 
ATOM   3029  C C   . ILE A 1 465 ? 129.130 99.570  132.871 1.00 104.67 ? 465 ILE A C   1 
ATOM   3030  O O   . ILE A 1 465 ? 128.459 100.586 132.739 1.00 107.47 ? 465 ILE A O   1 
ATOM   3031  C CB  . ILE A 1 465 ? 130.400 98.734  130.846 1.00 105.94 ? 465 ILE A CB  1 
ATOM   3032  C CG1 . ILE A 1 465 ? 131.788 98.412  130.256 1.00 102.54 ? 465 ILE A CG1 1 
ATOM   3033  C CG2 . ILE A 1 465 ? 129.588 99.621  129.899 1.00 100.67 ? 465 ILE A CG2 1 
ATOM   3034  C CD1 . ILE A 1 465 ? 131.738 97.781  128.867 1.00 102.05 ? 465 ILE A CD1 1 
ATOM   3035  N N   . SER A 1 466 ? 128.726 98.569  133.641 1.00 106.16 ? 466 SER A N   1 
ATOM   3036  C CA  . SER A 1 466 ? 127.451 98.547  134.351 1.00 112.64 ? 466 SER A CA  1 
ATOM   3037  C C   . SER A 1 466 ? 127.448 99.325  135.679 1.00 114.22 ? 466 SER A C   1 
ATOM   3038  O O   . SER A 1 466 ? 126.431 99.308  136.372 1.00 114.79 ? 466 SER A O   1 
ATOM   3039  C CB  . SER A 1 466 ? 127.023 97.096  134.538 1.00 111.27 ? 466 SER A CB  1 
ATOM   3040  O OG  . SER A 1 466 ? 127.004 96.457  133.274 1.00 111.10 ? 466 SER A OG  1 
ATOM   3041  N N   . PHE A 1 467 ? 128.529 100.036 136.039 1.00 115.98 ? 467 PHE A N   1 
ATOM   3042  C CA  . PHE A 1 467 ? 128.539 100.984 137.162 1.00 116.11 ? 467 PHE A CA  1 
ATOM   3043  C C   . PHE A 1 467 ? 129.262 102.321 136.904 1.00 116.59 ? 467 PHE A C   1 
ATOM   3044  O O   . PHE A 1 467 ? 129.136 103.223 137.725 1.00 117.59 ? 467 PHE A O   1 
ATOM   3045  C CB  . PHE A 1 467 ? 129.027 100.301 138.451 1.00 113.79 ? 467 PHE A CB  1 
ATOM   3046  C CG  . PHE A 1 467 ? 130.470 99.819  138.511 1.00 115.52 ? 467 PHE A CG  1 
ATOM   3047  C CD1 . PHE A 1 467 ? 131.544 100.730 138.484 1.00 114.44 ? 467 PHE A CD1 1 
ATOM   3048  C CD2 . PHE A 1 467 ? 130.742 98.455  138.730 1.00 114.61 ? 467 PHE A CD2 1 
ATOM   3049  C CE1 . PHE A 1 467 ? 132.860 100.284 138.669 1.00 115.95 ? 467 PHE A CE1 1 
ATOM   3050  C CE2 . PHE A 1 467 ? 132.058 98.011  138.931 1.00 113.31 ? 467 PHE A CE2 1 
ATOM   3051  C CZ  . PHE A 1 467 ? 133.122 98.924  138.901 1.00 114.49 ? 467 PHE A CZ  1 
ATOM   3052  N N   . MET A 1 468 ? 129.996 102.498 135.798 1.00 113.30 ? 468 MET A N   1 
ATOM   3053  C CA  . MET A 1 468 ? 130.806 103.706 135.541 1.00 113.33 ? 468 MET A CA  1 
ATOM   3054  C C   . MET A 1 468 ? 130.013 105.021 135.625 1.00 113.27 ? 468 MET A C   1 
ATOM   3055  O O   . MET A 1 468 ? 130.450 105.970 136.271 1.00 110.54 ? 468 MET A O   1 
ATOM   3056  C CB  . MET A 1 468 ? 131.535 103.593 134.186 1.00 113.12 ? 468 MET A CB  1 
ATOM   3057  C CG  . MET A 1 468 ? 130.644 103.167 133.008 1.00 112.44 ? 468 MET A CG  1 
ATOM   3058  S SD  . MET A 1 468 ? 131.378 103.194 131.346 1.00 118.64 ? 468 MET A SD  1 
ATOM   3059  C CE  . MET A 1 468 ? 132.941 102.306 131.592 1.00 110.66 ? 468 MET A CE  1 
ATOM   3060  N N   . ASP A 1 469 ? 128.825 105.065 135.020 1.00 106.55 ? 469 ASP A N   1 
ATOM   3061  C CA  . ASP A 1 469 ? 127.846 106.149 135.180 1.00 103.84 ? 469 ASP A CA  1 
ATOM   3062  C C   . ASP A 1 469 ? 126.823 105.848 136.290 1.00 102.04 ? 469 ASP A C   1 
ATOM   3063  O O   . ASP A 1 469 ? 126.337 106.750 136.964 1.00 102.81 ? 469 ASP A O   1 
ATOM   3064  C CB  . ASP A 1 469 ? 127.129 106.382 133.841 1.00 102.41 ? 469 ASP A CB  1 
ATOM   3065  C CG  . ASP A 1 469 ? 126.452 105.151 133.213 1.00 101.15 ? 469 ASP A CG  1 
ATOM   3066  O OD1 . ASP A 1 469 ? 126.378 104.074 133.848 1.00 101.33 ? 469 ASP A OD1 1 
ATOM   3067  O OD2 . ASP A 1 469 ? 126.003 105.277 132.057 1.00 101.95 ? 469 ASP A OD2 1 
ATOM   3068  N N   . SER A 1 470 ? 126.506 104.571 136.479 1.00 89.84  ? 470 SER A N   1 
ATOM   3069  C CA  . SER A 1 470 ? 125.465 104.033 137.344 1.00 86.55  ? 470 SER A CA  1 
ATOM   3070  C C   . SER A 1 470 ? 126.000 103.739 138.745 1.00 87.84  ? 470 SER A C   1 
ATOM   3071  O O   . SER A 1 470 ? 125.876 102.631 139.266 1.00 86.90  ? 470 SER A O   1 
ATOM   3072  C CB  . SER A 1 470 ? 124.851 102.804 136.669 1.00 89.15  ? 470 SER A CB  1 
ATOM   3073  O OG  . SER A 1 470 ? 124.351 103.153 135.390 1.00 96.00  ? 470 SER A OG  1 
ATOM   3074  N N   . TYR A 1 471 ? 126.608 104.743 139.375 1.00 78.52  ? 471 TYR A N   1 
ATOM   3075  C CA  . TYR A 1 471 ? 127.233 104.629 140.692 1.00 63.54  ? 471 TYR A CA  1 
ATOM   3076  C C   . TYR A 1 471 ? 126.261 104.263 141.819 1.00 61.30  ? 471 TYR A C   1 
ATOM   3077  O O   . TYR A 1 471 ? 126.668 103.629 142.789 1.00 65.75  ? 471 TYR A O   1 
ATOM   3078  C CB  . TYR A 1 471 ? 127.986 105.923 141.005 1.00 68.23  ? 471 TYR A CB  1 
ATOM   3079  C CG  . TYR A 1 471 ? 127.143 107.173 141.181 1.00 75.56  ? 471 TYR A CG  1 
ATOM   3080  C CD1 . TYR A 1 471 ? 126.623 107.493 142.449 1.00 72.53  ? 471 TYR A CD1 1 
ATOM   3081  C CD2 . TYR A 1 471 ? 126.947 108.064 140.108 1.00 73.72  ? 471 TYR A CD2 1 
ATOM   3082  C CE1 . TYR A 1 471 ? 125.955 108.714 142.658 1.00 73.74  ? 471 TYR A CE1 1 
ATOM   3083  C CE2 . TYR A 1 471 ? 126.254 109.275 140.303 1.00 72.45  ? 471 TYR A CE2 1 
ATOM   3084  C CZ  . TYR A 1 471 ? 125.780 109.613 141.585 1.00 77.60  ? 471 TYR A CZ  1 
ATOM   3085  O OH  . TYR A 1 471 ? 125.168 110.805 141.806 1.00 71.10  ? 471 TYR A OH  1 
ATOM   3086  N N   . PHE A 1 472 ? 124.967 104.562 141.696 1.00 62.58  ? 472 PHE A N   1 
ATOM   3087  C CA  . PHE A 1 472 ? 123.960 104.136 142.669 1.00 57.22  ? 472 PHE A CA  1 
ATOM   3088  C C   . PHE A 1 472 ? 123.862 102.616 142.804 1.00 62.26  ? 472 PHE A C   1 
ATOM   3089  O O   . PHE A 1 472 ? 123.524 102.135 143.875 1.00 74.38  ? 472 PHE A O   1 
ATOM   3090  C CB  . PHE A 1 472 ? 122.588 104.711 142.323 1.00 52.47  ? 472 PHE A CB  1 
ATOM   3091  C CG  . PHE A 1 472 ? 122.437 106.188 142.598 1.00 59.78  ? 472 PHE A CG  1 
ATOM   3092  C CD1 . PHE A 1 472 ? 122.218 106.629 143.910 1.00 57.98  ? 472 PHE A CD1 1 
ATOM   3093  C CD2 . PHE A 1 472 ? 122.486 107.116 141.547 1.00 62.03  ? 472 PHE A CD2 1 
ATOM   3094  C CE1 . PHE A 1 472 ? 122.057 107.998 144.173 1.00 54.08  ? 472 PHE A CE1 1 
ATOM   3095  C CE2 . PHE A 1 472 ? 122.305 108.482 141.808 1.00 61.32  ? 472 PHE A CE2 1 
ATOM   3096  C CZ  . PHE A 1 472 ? 122.091 108.922 143.120 1.00 56.01  ? 472 PHE A CZ  1 
ATOM   3097  N N   . GLU A 1 473 ? 124.198 101.822 141.792 1.00 74.94  ? 473 GLU A N   1 
ATOM   3098  C CA  . GLU A 1 473 ? 124.115 100.363 141.926 1.00 70.37  ? 473 GLU A CA  1 
ATOM   3099  C C   . GLU A 1 473 ? 125.133 99.810  142.936 1.00 75.39  ? 473 GLU A C   1 
ATOM   3100  O O   . GLU A 1 473 ? 124.874 98.790  143.574 1.00 80.03  ? 473 GLU A O   1 
ATOM   3101  C CB  . GLU A 1 473 ? 124.238 99.699  140.544 1.00 74.11  ? 473 GLU A CB  1 
ATOM   3102  C CG  . GLU A 1 473 ? 123.174 100.174 139.536 1.00 79.50  ? 473 GLU A CG  1 
ATOM   3103  C CD  . GLU A 1 473 ? 121.733 100.105 140.069 1.00 88.41  ? 473 GLU A CD  1 
ATOM   3104  O OE1 . GLU A 1 473 ? 121.381 99.174  140.829 1.00 90.00  ? 473 GLU A OE1 1 
ATOM   3105  O OE2 . GLU A 1 473 ? 120.926 101.019 139.776 1.00 86.46  ? 473 GLU A OE2 1 
ATOM   3106  N N   . ILE A 1 474 ? 126.251 100.515 143.150 1.00 69.67  ? 474 ILE A N   1 
ATOM   3107  C CA  . ILE A 1 474 ? 127.219 100.256 144.223 1.00 61.40  ? 474 ILE A CA  1 
ATOM   3108  C C   . ILE A 1 474 ? 126.710 100.795 145.563 1.00 68.67  ? 474 ILE A C   1 
ATOM   3109  O O   . ILE A 1 474 ? 126.799 100.107 146.574 1.00 71.68  ? 474 ILE A O   1 
ATOM   3110  C CB  . ILE A 1 474 ? 128.586 100.883 143.877 1.00 67.07  ? 474 ILE A CB  1 
ATOM   3111  C CG1 . ILE A 1 474 ? 129.167 100.303 142.575 1.00 68.54  ? 474 ILE A CG1 1 
ATOM   3112  C CG2 . ILE A 1 474 ? 129.580 100.684 145.031 1.00 68.27  ? 474 ILE A CG2 1 
ATOM   3113  C CD1 . ILE A 1 474 ? 130.344 101.107 142.041 1.00 67.05  ? 474 ILE A CD1 1 
ATOM   3114  N N   . LEU A 1 475 ? 126.162 102.016 145.603 1.00 63.79  ? 475 LEU A N   1 
ATOM   3115  C CA  . LEU A 1 475 ? 125.684 102.643 146.838 1.00 57.95  ? 475 LEU A CA  1 
ATOM   3116  C C   . LEU A 1 475 ? 124.466 101.944 147.451 1.00 58.64  ? 475 LEU A C   1 
ATOM   3117  O O   . LEU A 1 475 ? 124.328 101.908 148.670 1.00 75.08  ? 475 LEU A O   1 
ATOM   3118  C CB  . LEU A 1 475 ? 125.361 104.122 146.602 1.00 52.18  ? 475 LEU A CB  1 
ATOM   3119  C CG  . LEU A 1 475 ? 126.499 105.007 146.084 1.00 53.83  ? 475 LEU A CG  1 
ATOM   3120  C CD1 . LEU A 1 475 ? 125.980 106.433 145.949 1.00 61.18  ? 475 LEU A CD1 1 
ATOM   3121  C CD2 . LEU A 1 475 ? 127.702 105.018 147.017 1.00 62.21  ? 475 LEU A CD2 1 
ATOM   3122  N N   . PHE A 1 476 ? 123.594 101.337 146.651 1.00 43.86  ? 476 PHE A N   1 
ATOM   3123  C CA  . PHE A 1 476 ? 122.538 100.456 147.146 1.00 47.58  ? 476 PHE A CA  1 
ATOM   3124  C C   . PHE A 1 476 ? 123.097 99.126  147.693 1.00 55.39  ? 476 PHE A C   1 
ATOM   3125  O O   . PHE A 1 476 ? 122.493 98.551  148.592 1.00 56.75  ? 476 PHE A O   1 
ATOM   3126  C CB  . PHE A 1 476 ? 121.489 100.236 146.047 1.00 50.15  ? 476 PHE A CB  1 
ATOM   3127  C CG  . PHE A 1 476 ? 120.375 101.271 145.985 1.00 52.49  ? 476 PHE A CG  1 
ATOM   3128  C CD1 . PHE A 1 476 ? 120.552 102.499 145.329 1.00 61.16  ? 476 PHE A CD1 1 
ATOM   3129  C CD2 . PHE A 1 476 ? 119.121 100.981 146.546 1.00 57.65  ? 476 PHE A CD2 1 
ATOM   3130  C CE1 . PHE A 1 476 ? 119.493 103.411 145.216 1.00 59.08  ? 476 PHE A CE1 1 
ATOM   3131  C CE2 . PHE A 1 476 ? 118.057 101.891 146.434 1.00 54.90  ? 476 PHE A CE2 1 
ATOM   3132  C CZ  . PHE A 1 476 ? 118.243 103.103 145.765 1.00 44.60  ? 476 PHE A CZ  1 
ATOM   3133  N N   . LEU A 1 477 ? 124.188 98.599  147.130 1.00 63.51  ? 477 LEU A N   1 
ATOM   3134  C CA  . LEU A 1 477 ? 124.813 97.368  147.613 1.00 62.57  ? 477 LEU A CA  1 
ATOM   3135  C C   . LEU A 1 477 ? 125.517 97.638  148.937 1.00 68.00  ? 477 LEU A C   1 
ATOM   3136  O O   . LEU A 1 477 ? 125.354 96.890  149.893 1.00 75.20  ? 477 LEU A O   1 
ATOM   3137  C CB  . LEU A 1 477 ? 125.788 96.818  146.555 1.00 65.39  ? 477 LEU A CB  1 
ATOM   3138  C CG  . LEU A 1 477 ? 126.554 95.560  146.998 1.00 63.61  ? 477 LEU A CG  1 
ATOM   3139  C CD1 . LEU A 1 477 ? 125.634 94.361  147.158 1.00 69.22  ? 477 LEU A CD1 1 
ATOM   3140  C CD2 . LEU A 1 477 ? 127.624 95.192  145.980 1.00 67.88  ? 477 LEU A CD2 1 
ATOM   3141  N N   . LEU A 1 478 ? 126.232 98.755  149.021 1.00 68.90  ? 478 LEU A N   1 
ATOM   3142  C CA  . LEU A 1 478 ? 126.890 99.230  150.224 1.00 63.58  ? 478 LEU A CA  1 
ATOM   3143  C C   . LEU A 1 478 ? 125.884 99.520  151.346 1.00 66.04  ? 478 LEU A C   1 
ATOM   3144  O O   . LEU A 1 478 ? 126.062 99.033  152.456 1.00 73.97  ? 478 LEU A O   1 
ATOM   3145  C CB  . LEU A 1 478 ? 127.731 100.451 149.830 1.00 61.06  ? 478 LEU A CB  1 
ATOM   3146  C CG  . LEU A 1 478 ? 128.551 101.058 150.969 1.00 70.78  ? 478 LEU A CG  1 
ATOM   3147  C CD1 . LEU A 1 478 ? 129.583 100.081 151.518 1.00 67.47  ? 478 LEU A CD1 1 
ATOM   3148  C CD2 . LEU A 1 478 ? 129.265 102.300 150.450 1.00 66.46  ? 478 LEU A CD2 1 
ATOM   3149  N N   . GLN A 1 479 ? 124.787 100.235 151.083 1.00 61.27  ? 479 GLN A N   1 
ATOM   3150  C CA  . GLN A 1 479 ? 123.751 100.469 152.097 1.00 60.88  ? 479 GLN A CA  1 
ATOM   3151  C C   . GLN A 1 479 ? 123.127 99.162  152.595 1.00 65.39  ? 479 GLN A C   1 
ATOM   3152  O O   . GLN A 1 479 ? 122.907 99.003  153.794 1.00 69.90  ? 479 GLN A O   1 
ATOM   3153  C CB  . GLN A 1 479 ? 122.682 101.413 151.539 1.00 59.59  ? 479 GLN A CB  1 
ATOM   3154  C CG  . GLN A 1 479 ? 121.817 102.080 152.615 1.00 59.32  ? 479 GLN A CG  1 
ATOM   3155  C CD  . GLN A 1 479 ? 120.559 101.347 153.084 1.00 65.46  ? 479 GLN A CD  1 
ATOM   3156  O OE1 . GLN A 1 479 ? 120.136 100.331 152.565 1.00 66.75  ? 479 GLN A OE1 1 
ATOM   3157  N NE2 . GLN A 1 479 ? 119.906 101.866 154.094 1.00 70.64  ? 479 GLN A NE2 1 
ATOM   3158  N N   . ALA A 1 480 ? 122.896 98.196  151.710 1.00 76.74  ? 480 ALA A N   1 
ATOM   3159  C CA  . ALA A 1 480 ? 122.360 96.896  152.072 1.00 69.31  ? 480 ALA A CA  1 
ATOM   3160  C C   . ALA A 1 480 ? 123.361 96.051  152.876 1.00 74.78  ? 480 ALA A C   1 
ATOM   3161  O O   . ALA A 1 480 ? 122.987 95.492  153.904 1.00 78.14  ? 480 ALA A O   1 
ATOM   3162  C CB  . ALA A 1 480 ? 121.930 96.197  150.793 1.00 70.98  ? 480 ALA A CB  1 
ATOM   3163  N N   . LEU A 1 481 ? 124.642 96.010  152.490 1.00 71.76  ? 481 LEU A N   1 
ATOM   3164  C CA  . LEU A 1 481 ? 125.691 95.345  153.269 1.00 72.24  ? 481 LEU A CA  1 
ATOM   3165  C C   . LEU A 1 481 ? 125.792 95.933  154.676 1.00 76.52  ? 481 LEU A C   1 
ATOM   3166  O O   . LEU A 1 481 ? 125.762 95.189  155.649 1.00 79.03  ? 481 LEU A O   1 
ATOM   3167  C CB  . LEU A 1 481 ? 127.053 95.463  152.563 1.00 73.51  ? 481 LEU A CB  1 
ATOM   3168  C CG  . LEU A 1 481 ? 127.268 94.484  151.402 1.00 82.94  ? 481 LEU A CG  1 
ATOM   3169  C CD1 . LEU A 1 481 ? 128.555 94.838  150.666 1.00 76.30  ? 481 LEU A CD1 1 
ATOM   3170  C CD2 . LEU A 1 481 ? 127.404 93.047  151.892 1.00 77.92  ? 481 LEU A CD2 1 
ATOM   3171  N N   . LEU A 1 482 ? 125.862 97.257  154.805 1.00 76.55  ? 482 LEU A N   1 
ATOM   3172  C CA  . LEU A 1 482 ? 125.943 97.940  156.096 1.00 72.27  ? 482 LEU A CA  1 
ATOM   3173  C C   . LEU A 1 482 ? 124.665 97.792  156.933 1.00 64.27  ? 482 LEU A C   1 
ATOM   3174  O O   . LEU A 1 482 ? 124.729 97.765  158.159 1.00 72.04  ? 482 LEU A O   1 
ATOM   3175  C CB  . LEU A 1 482 ? 126.240 99.417  155.839 1.00 71.58  ? 482 LEU A CB  1 
ATOM   3176  C CG  . LEU A 1 482 ? 127.618 99.710  155.235 1.00 67.91  ? 482 LEU A CG  1 
ATOM   3177  C CD1 . LEU A 1 482 ? 127.621 101.160 154.774 1.00 70.06  ? 482 LEU A CD1 1 
ATOM   3178  C CD2 . LEU A 1 482 ? 128.729 99.529  156.261 1.00 70.13  ? 482 LEU A CD2 1 
ATOM   3179  N N   . THR A 1 483 ? 123.501 97.640  156.308 1.00 68.00  ? 483 THR A N   1 
ATOM   3180  C CA  . THR A 1 483 ? 122.259 97.307  157.013 1.00 72.39  ? 483 THR A CA  1 
ATOM   3181  C C   . THR A 1 483 ? 122.300 95.887  157.573 1.00 73.24  ? 483 THR A C   1 
ATOM   3182  O O   . THR A 1 483 ? 121.987 95.674  158.734 1.00 75.21  ? 483 THR A O   1 
ATOM   3183  C CB  . THR A 1 483 ? 121.041 97.474  156.101 1.00 80.53  ? 483 THR A CB  1 
ATOM   3184  O OG1 . THR A 1 483 ? 120.986 98.803  155.664 1.00 80.48  ? 483 THR A OG1 1 
ATOM   3185  C CG2 . THR A 1 483 ? 119.735 97.178  156.822 1.00 71.64  ? 483 THR A CG2 1 
ATOM   3186  N N   . VAL A 1 484 ? 122.747 94.898  156.799 1.00 82.75  ? 484 VAL A N   1 
ATOM   3187  C CA  . VAL A 1 484 ? 122.893 93.525  157.300 1.00 81.58  ? 484 VAL A CA  1 
ATOM   3188  C C   . VAL A 1 484 ? 123.994 93.437  158.363 1.00 83.07  ? 484 VAL A C   1 
ATOM   3189  O O   . VAL A 1 484 ? 123.756 92.895  159.437 1.00 86.93  ? 484 VAL A O   1 
ATOM   3190  C CB  . VAL A 1 484 ? 123.111 92.540  156.138 1.00 86.26  ? 484 VAL A CB  1 
ATOM   3191  C CG1 . VAL A 1 484 ? 123.356 91.116  156.631 1.00 86.75  ? 484 VAL A CG1 1 
ATOM   3192  C CG2 . VAL A 1 484 ? 121.870 92.505  155.247 1.00 82.75  ? 484 VAL A CG2 1 
ATOM   3193  N N   . LEU A 1 485 ? 125.165 94.037  158.141 1.00 80.61  ? 485 LEU A N   1 
ATOM   3194  C CA  . LEU A 1 485 ? 126.244 94.094  159.129 1.00 80.94  ? 485 LEU A CA  1 
ATOM   3195  C C   . LEU A 1 485 ? 125.801 94.763  160.431 1.00 85.82  ? 485 LEU A C   1 
ATOM   3196  O O   . LEU A 1 485 ? 126.075 94.228  161.498 1.00 86.24  ? 485 LEU A O   1 
ATOM   3197  C CB  . LEU A 1 485 ? 127.457 94.844  158.557 1.00 84.50  ? 485 LEU A CB  1 
ATOM   3198  C CG  . LEU A 1 485 ? 128.244 94.058  157.502 1.00 90.64  ? 485 LEU A CG  1 
ATOM   3199  C CD1 . LEU A 1 485 ? 129.176 94.998  156.745 1.00 88.55  ? 485 LEU A CD1 1 
ATOM   3200  C CD2 . LEU A 1 485 ? 129.092 92.971  158.156 1.00 87.71  ? 485 LEU A CD2 1 
ATOM   3201  N N   . SER A 1 486 ? 125.102 95.898  160.391 1.00 86.92  ? 486 SER A N   1 
ATOM   3202  C CA  . SER A 1 486 ? 124.648 96.559  161.620 1.00 76.72  ? 486 SER A CA  1 
ATOM   3203  C C   . SER A 1 486 ? 123.632 95.717  162.390 1.00 78.28  ? 486 SER A C   1 
ATOM   3204  O O   . SER A 1 486 ? 123.758 95.604  163.602 1.00 90.53  ? 486 SER A O   1 
ATOM   3205  C CB  . SER A 1 486 ? 124.109 97.963  161.349 1.00 76.02  ? 486 SER A CB  1 
ATOM   3206  O OG  . SER A 1 486 ? 123.101 97.961  160.374 1.00 86.59  ? 486 SER A OG  1 
ATOM   3207  N N   . GLN A 1 487 ? 122.684 95.034  161.746 1.00 83.93  ? 487 GLN A N   1 
ATOM   3208  C CA  . GLN A 1 487 ? 121.816 94.112  162.485 1.00 85.26  ? 487 GLN A CA  1 
ATOM   3209  C C   . GLN A 1 487 ? 122.587 92.892  163.026 1.00 85.82  ? 487 GLN A C   1 
ATOM   3210  O O   . GLN A 1 487 ? 122.335 92.475  164.149 1.00 88.76  ? 487 GLN A O   1 
ATOM   3211  C CB  . GLN A 1 487 ? 120.611 93.690  161.637 1.00 88.33  ? 487 GLN A CB  1 
ATOM   3212  C CG  . GLN A 1 487 ? 119.721 94.848  161.164 1.00 86.78  ? 487 GLN A CG  1 
ATOM   3213  C CD  . GLN A 1 487 ? 119.305 95.831  162.248 1.00 89.38  ? 487 GLN A CD  1 
ATOM   3214  O OE1 . GLN A 1 487 ? 118.957 95.481  163.364 1.00 91.01  ? 487 GLN A OE1 1 
ATOM   3215  N NE2 . GLN A 1 487 ? 119.313 97.108  161.959 1.00 89.29  ? 487 GLN A NE2 1 
ATOM   3216  N N   . VAL A 1 488 ? 123.585 92.367  162.307 1.00 91.75  ? 488 VAL A N   1 
ATOM   3217  C CA  . VAL A 1 488 ? 124.478 91.305  162.804 1.00 93.52  ? 488 VAL A CA  1 
ATOM   3218  C C   . VAL A 1 488 ? 125.272 91.759  164.029 1.00 96.00  ? 488 VAL A C   1 
ATOM   3219  O O   . VAL A 1 488 ? 125.268 91.067  165.043 1.00 93.73  ? 488 VAL A O   1 
ATOM   3220  C CB  . VAL A 1 488 ? 125.392 90.793  161.676 1.00 93.22  ? 488 VAL A CB  1 
ATOM   3221  C CG1 . VAL A 1 488 ? 126.567 89.949  162.166 1.00 92.26  ? 488 VAL A CG1 1 
ATOM   3222  C CG2 . VAL A 1 488 ? 124.582 89.933  160.706 1.00 90.89  ? 488 VAL A CG2 1 
ATOM   3223  N N   . LEU A 1 489 ? 125.894 92.939  164.006 1.00 93.65  ? 489 LEU A N   1 
ATOM   3224  C CA  . LEU A 1 489 ? 126.581 93.494  165.172 1.00 87.51  ? 489 LEU A CA  1 
ATOM   3225  C C   . LEU A 1 489 ? 125.617 93.773  166.335 1.00 84.41  ? 489 LEU A C   1 
ATOM   3226  O O   . LEU A 1 489 ? 126.002 93.611  167.490 1.00 88.63  ? 489 LEU A O   1 
ATOM   3227  C CB  . LEU A 1 489 ? 127.355 94.767  164.794 1.00 89.70  ? 489 LEU A CB  1 
ATOM   3228  C CG  . LEU A 1 489 ? 128.538 94.596  163.827 1.00 88.76  ? 489 LEU A CG  1 
ATOM   3229  C CD1 . LEU A 1 489 ? 129.435 95.822  163.933 1.00 89.65  ? 489 LEU A CD1 1 
ATOM   3230  C CD2 . LEU A 1 489 ? 129.406 93.378  164.110 1.00 89.80  ? 489 LEU A CD2 1 
ATOM   3231  N N   . ARG A 1 490 ? 124.360 94.139  166.068 1.00 92.32  ? 490 ARG A N   1 
ATOM   3232  C CA  . ARG A 1 490 ? 123.334 94.304  167.108 1.00 95.76  ? 490 ARG A CA  1 
ATOM   3233  C C   . ARG A 1 490 ? 122.912 92.972  167.733 1.00 98.36  ? 490 ARG A C   1 
ATOM   3234  O O   . ARG A 1 490 ? 122.753 92.908  168.946 1.00 98.32  ? 490 ARG A O   1 
ATOM   3235  C CB  . ARG A 1 490 ? 122.129 95.056  166.536 1.00 91.66  ? 490 ARG A CB  1 
ATOM   3236  C CG  . ARG A 1 490 ? 121.212 95.592  167.633 1.00 93.05  ? 490 ARG A CG  1 
ATOM   3237  C CD  . ARG A 1 490 ? 119.925 96.158  167.044 1.00 96.95  ? 490 ARG A CD  1 
ATOM   3238  N NE  . ARG A 1 490 ? 119.032 95.082  166.569 1.00 102.94 ? 490 ARG A NE  1 
ATOM   3239  C CZ  . ARG A 1 490 ? 118.149 94.411  167.288 1.00 100.46 ? 490 ARG A CZ  1 
ATOM   3240  N NH1 . ARG A 1 490 ? 117.461 93.449  166.752 1.00 97.88  ? 490 ARG A NH1 1 
ATOM   3241  N NH2 . ARG A 1 490 ? 117.938 94.667  168.544 1.00 95.76  ? 490 ARG A NH2 1 
ATOM   3242  N N   . PHE A 1 491 ? 122.795 91.891  166.961 1.00 107.25 ? 491 PHE A N   1 
ATOM   3243  C CA  . PHE A 1 491 ? 122.602 90.538  167.505 1.00 102.87 ? 491 PHE A CA  1 
ATOM   3244  C C   . PHE A 1 491 ? 123.826 90.044  168.297 1.00 105.29 ? 491 PHE A C   1 
ATOM   3245  O O   . PHE A 1 491 ? 123.666 89.389  169.324 1.00 104.73 ? 491 PHE A O   1 
ATOM   3246  C CB  . PHE A 1 491 ? 122.254 89.555  166.377 1.00 99.98  ? 491 PHE A CB  1 
ATOM   3247  N N   . MET A 1 492 ? 125.044 90.419  167.897 1.00 109.59 ? 492 MET A N   1 
ATOM   3248  C CA  . MET A 1 492 ? 126.267 90.240  168.698 1.00 108.71 ? 492 MET A CA  1 
ATOM   3249  C C   . MET A 1 492 ? 126.351 91.172  169.925 1.00 108.22 ? 492 MET A C   1 
ATOM   3250  O O   . MET A 1 492 ? 127.248 91.026  170.750 1.00 105.26 ? 492 MET A O   1 
ATOM   3251  C CB  . MET A 1 492 ? 127.504 90.456  167.810 1.00 109.49 ? 492 MET A CB  1 
ATOM   3252  C CG  . MET A 1 492 ? 127.676 89.384  166.733 1.00 110.54 ? 492 MET A CG  1 
ATOM   3253  S SD  . MET A 1 492 ? 128.893 89.803  165.453 1.00 118.38 ? 492 MET A SD  1 
ATOM   3254  C CE  . MET A 1 492 ? 130.392 90.026  166.440 1.00 108.24 ? 492 MET A CE  1 
ATOM   3255  N N   . GLU A 1 493 ? 125.447 92.142  170.049 1.00 107.86 ? 493 GLU A N   1 
ATOM   3256  C CA  . GLU A 1 493 ? 125.412 93.171  171.091 1.00 106.51 ? 493 GLU A CA  1 
ATOM   3257  C C   . GLU A 1 493 ? 126.657 94.070  171.198 1.00 107.51 ? 493 GLU A C   1 
ATOM   3258  O O   . GLU A 1 493 ? 126.822 94.763  172.200 1.00 104.24 ? 493 GLU A O   1 
ATOM   3259  C CB  . GLU A 1 493 ? 125.026 92.540  172.428 1.00 102.15 ? 493 GLU A CB  1 
ATOM   3260  N N   . THR A 1 494 ? 127.537 94.100  170.188 1.00 107.39 ? 494 THR A N   1 
ATOM   3261  C CA  . THR A 1 494 ? 128.690 95.019  170.173 1.00 105.79 ? 494 THR A CA  1 
ATOM   3262  C C   . THR A 1 494 ? 128.258 96.429  169.778 1.00 104.04 ? 494 THR A C   1 
ATOM   3263  O O   . THR A 1 494 ? 127.544 96.629  168.798 1.00 104.39 ? 494 THR A O   1 
ATOM   3264  C CB  . THR A 1 494 ? 129.852 94.514  169.305 1.00 103.90 ? 494 THR A CB  1 
ATOM   3265  O OG1 . THR A 1 494 ? 130.929 95.420  169.378 1.00 100.79 ? 494 THR A OG1 1 
ATOM   3266  C CG2 . THR A 1 494 ? 129.545 94.363  167.825 1.00 103.17 ? 494 THR A CG2 1 
ATOM   3267  N N   . GLU A 1 495 ? 128.680 97.437  170.536 1.00 105.44 ? 495 GLU A N   1 
ATOM   3268  C CA  . GLU A 1 495 ? 128.169 98.808  170.417 1.00 106.45 ? 495 GLU A CA  1 
ATOM   3269  C C   . GLU A 1 495 ? 128.561 99.504  169.104 1.00 107.61 ? 495 GLU A C   1 
ATOM   3270  O O   . GLU A 1 495 ? 127.921 100.471 168.698 1.00 109.11 ? 495 GLU A O   1 
ATOM   3271  C CB  . GLU A 1 495 ? 128.604 99.629  171.639 1.00 102.70 ? 495 GLU A CB  1 
ATOM   3272  N N   . TRP A 1 496 ? 129.545 98.964  168.381 1.00 99.76  ? 496 TRP A N   1 
ATOM   3273  C CA  . TRP A 1 496 ? 129.873 99.360  167.009 1.00 97.49  ? 496 TRP A CA  1 
ATOM   3274  C C   . TRP A 1 496 ? 128.756 99.084  165.991 1.00 99.32  ? 496 TRP A C   1 
ATOM   3275  O O   . TRP A 1 496 ? 128.861 99.529  164.850 1.00 96.98  ? 496 TRP A O   1 
ATOM   3276  C CB  . TRP A 1 496 ? 131.189 98.701  166.589 1.00 94.98  ? 496 TRP A CB  1 
ATOM   3277  C CG  . TRP A 1 496 ? 132.395 99.316  167.226 1.00 103.23 ? 496 TRP A CG  1 
ATOM   3278  C CD1 . TRP A 1 496 ? 133.057 98.840  168.301 1.00 100.44 ? 496 TRP A CD1 1 
ATOM   3279  C CD2 . TRP A 1 496 ? 133.069 100.560 166.859 1.00 109.18 ? 496 TRP A CD2 1 
ATOM   3280  N NE1 . TRP A 1 496 ? 134.080 99.704  168.635 1.00 99.22  ? 496 TRP A NE1 1 
ATOM   3281  C CE2 . TRP A 1 496 ? 134.126 100.789 167.787 1.00 103.51 ? 496 TRP A CE2 1 
ATOM   3282  C CE3 . TRP A 1 496 ? 132.902 101.511 165.831 1.00 105.22 ? 496 TRP A CE3 1 
ATOM   3283  C CZ2 . TRP A 1 496 ? 134.950 101.918 167.718 1.00 98.13  ? 496 TRP A CZ2 1 
ATOM   3284  C CZ3 . TRP A 1 496 ? 133.726 102.650 165.750 1.00 99.23  ? 496 TRP A CZ3 1 
ATOM   3285  C CH2 . TRP A 1 496 ? 134.744 102.857 166.694 1.00 97.38  ? 496 TRP A CH2 1 
ATOM   3286  N N   . TYR A 1 497 ? 127.653 98.426  166.367 1.00 94.58  ? 497 TYR A N   1 
ATOM   3287  C CA  . TYR A 1 497 ? 126.469 98.373  165.511 1.00 90.36  ? 497 TYR A CA  1 
ATOM   3288  C C   . TYR A 1 497 ? 125.904 99.767  165.226 1.00 92.98  ? 497 TYR A C   1 
ATOM   3289  O O   . TYR A 1 497 ? 125.436 100.001 164.113 1.00 100.88 ? 497 TYR A O   1 
ATOM   3290  C CB  . TYR A 1 497 ? 125.385 97.466  166.110 1.00 89.65  ? 497 TYR A CB  1 
ATOM   3291  C CG  . TYR A 1 497 ? 124.364 98.144  167.000 1.00 90.64  ? 497 TYR A CG  1 
ATOM   3292  C CD1 . TYR A 1 497 ? 123.260 98.812  166.434 1.00 85.98  ? 497 TYR A CD1 1 
ATOM   3293  C CD2 . TYR A 1 497 ? 124.517 98.110  168.394 1.00 93.44  ? 497 TYR A CD2 1 
ATOM   3294  C CE1 . TYR A 1 497 ? 122.339 99.484  167.258 1.00 88.42  ? 497 TYR A CE1 1 
ATOM   3295  C CE2 . TYR A 1 497 ? 123.591 98.762  169.220 1.00 95.63  ? 497 TYR A CE2 1 
ATOM   3296  C CZ  . TYR A 1 497 ? 122.510 99.463  168.656 1.00 97.16  ? 497 TYR A CZ  1 
ATOM   3297  O OH  . TYR A 1 497 ? 121.634 100.097 169.474 1.00 97.91  ? 497 TYR A OH  1 
ATOM   3298  N N   . LEU A 1 498 ? 125.940 100.708 166.177 1.00 77.40  ? 498 LEU A N   1 
ATOM   3299  C CA  . LEU A 1 498 ? 125.280 102.005 166.008 1.00 79.30  ? 498 LEU A CA  1 
ATOM   3300  C C   . LEU A 1 498 ? 125.936 102.898 164.942 1.00 80.36  ? 498 LEU A C   1 
ATOM   3301  O O   . LEU A 1 498 ? 125.209 103.386 164.083 1.00 84.67  ? 498 LEU A O   1 
ATOM   3302  C CB  . LEU A 1 498 ? 125.106 102.713 167.359 1.00 76.11  ? 498 LEU A CB  1 
ATOM   3303  C CG  . LEU A 1 498 ? 124.292 104.012 167.252 1.00 76.53  ? 498 LEU A CG  1 
ATOM   3304  C CD1 . LEU A 1 498 ? 122.844 103.763 166.838 1.00 74.23  ? 498 LEU A CD1 1 
ATOM   3305  C CD2 . LEU A 1 498 ? 124.280 104.731 168.591 1.00 80.25  ? 498 LEU A CD2 1 
ATOM   3306  N N   . PRO A 1 499 ? 127.266 103.091 164.894 1.00 77.12  ? 499 PRO A N   1 
ATOM   3307  C CA  . PRO A 1 499 ? 127.884 103.842 163.803 1.00 77.13  ? 499 PRO A CA  1 
ATOM   3308  C C   . PRO A 1 499 ? 127.719 103.195 162.414 1.00 79.13  ? 499 PRO A C   1 
ATOM   3309  O O   . PRO A 1 499 ? 127.701 103.912 161.420 1.00 73.14  ? 499 PRO A O   1 
ATOM   3310  C CB  . PRO A 1 499 ? 129.344 104.039 164.217 1.00 73.78  ? 499 PRO A CB  1 
ATOM   3311  C CG  . PRO A 1 499 ? 129.602 102.947 165.242 1.00 76.72  ? 499 PRO A CG  1 
ATOM   3312  C CD  . PRO A 1 499 ? 128.250 102.795 165.921 1.00 77.67  ? 499 PRO A CD  1 
ATOM   3313  N N   . LEU A 1 500 ? 127.516 101.875 162.302 1.00 80.90  ? 500 LEU A N   1 
ATOM   3314  C CA  . LEU A 1 500 ? 127.132 101.239 161.032 1.00 75.15  ? 500 LEU A CA  1 
ATOM   3315  C C   . LEU A 1 500 ? 125.661 101.480 160.680 1.00 73.29  ? 500 LEU A C   1 
ATOM   3316  O O   . LEU A 1 500 ? 125.340 101.728 159.517 1.00 84.41  ? 500 LEU A O   1 
ATOM   3317  C CB  . LEU A 1 500 ? 127.391 99.725  161.066 1.00 76.01  ? 500 LEU A CB  1 
ATOM   3318  C CG  . LEU A 1 500 ? 128.844 99.254  161.173 1.00 75.82  ? 500 LEU A CG  1 
ATOM   3319  C CD1 . LEU A 1 500 ? 128.863 97.746  160.942 1.00 81.98  ? 500 LEU A CD1 1 
ATOM   3320  C CD2 . LEU A 1 500 ? 129.758 99.873  160.124 1.00 69.27  ? 500 LEU A CD2 1 
ATOM   3321  N N   . LEU A 1 501 ? 124.755 101.429 161.659 1.00 63.90  ? 501 LEU A N   1 
ATOM   3322  C CA  . LEU A 1 501 ? 123.337 101.731 161.440 1.00 69.74  ? 501 LEU A CA  1 
ATOM   3323  C C   . LEU A 1 501 ? 123.167 103.183 160.988 1.00 71.58  ? 501 LEU A C   1 
ATOM   3324  O O   . LEU A 1 501 ? 122.455 103.476 160.040 1.00 81.07  ? 501 LEU A O   1 
ATOM   3325  C CB  . LEU A 1 501 ? 122.546 101.445 162.728 1.00 70.50  ? 501 LEU A CB  1 
ATOM   3326  C CG  . LEU A 1 501 ? 121.033 101.680 162.589 1.00 68.73  ? 501 LEU A CG  1 
ATOM   3327  C CD1 . LEU A 1 501 ? 120.389 100.591 161.741 1.00 73.45  ? 501 LEU A CD1 1 
ATOM   3328  C CD2 . LEU A 1 501 ? 120.370 101.654 163.963 1.00 72.32  ? 501 LEU A CD2 1 
ATOM   3329  N N   . VAL A 1 502 ? 123.881 104.103 161.616 1.00 70.79  ? 502 VAL A N   1 
ATOM   3330  C CA  . VAL A 1 502 ? 123.858 105.524 161.275 1.00 70.10  ? 502 VAL A CA  1 
ATOM   3331  C C   . VAL A 1 502 ? 124.517 105.811 159.921 1.00 68.54  ? 502 VAL A C   1 
ATOM   3332  O O   . VAL A 1 502 ? 123.991 106.602 159.150 1.00 75.63  ? 502 VAL A O   1 
ATOM   3333  C CB  . VAL A 1 502 ? 124.476 106.306 162.438 1.00 74.86  ? 502 VAL A CB  1 
ATOM   3334  C CG1 . VAL A 1 502 ? 124.758 107.750 162.067 1.00 72.92  ? 502 VAL A CG1 1 
ATOM   3335  C CG2 . VAL A 1 502 ? 123.487 106.307 163.611 1.00 66.06  ? 502 VAL A CG2 1 
ATOM   3336  N N   . LEU A 1 503 ? 125.606 105.138 159.546 1.00 73.77  ? 503 LEU A N   1 
ATOM   3337  C CA  . LEU A 1 503 ? 126.168 105.266 158.199 1.00 76.85  ? 503 LEU A CA  1 
ATOM   3338  C C   . LEU A 1 503 ? 125.194 104.765 157.121 1.00 72.81  ? 503 LEU A C   1 
ATOM   3339  O O   . LEU A 1 503 ? 124.993 105.426 156.105 1.00 73.91  ? 503 LEU A O   1 
ATOM   3340  C CB  . LEU A 1 503 ? 127.517 104.528 158.144 1.00 72.50  ? 503 LEU A CB  1 
ATOM   3341  C CG  . LEU A 1 503 ? 128.186 104.554 156.760 1.00 77.59  ? 503 LEU A CG  1 
ATOM   3342  C CD1 . LEU A 1 503 ? 128.495 105.970 156.277 1.00 77.23  ? 503 LEU A CD1 1 
ATOM   3343  C CD2 . LEU A 1 503 ? 129.491 103.770 156.813 1.00 76.72  ? 503 LEU A CD2 1 
ATOM   3344  N N   . SER A 1 504 ? 124.556 103.616 157.339 1.00 68.80  ? 504 SER A N   1 
ATOM   3345  C CA  . SER A 1 504 ? 123.556 103.075 156.415 1.00 63.24  ? 504 SER A CA  1 
ATOM   3346  C C   . SER A 1 504 ? 122.245 103.865 156.406 1.00 65.76  ? 504 SER A C   1 
ATOM   3347  O O   . SER A 1 504 ? 121.562 103.868 155.388 1.00 79.83  ? 504 SER A O   1 
ATOM   3348  C CB  . SER A 1 504 ? 123.325 101.591 156.669 1.00 66.12  ? 504 SER A CB  1 
ATOM   3349  O OG  . SER A 1 504 ? 123.062 101.310 158.013 1.00 73.89  ? 504 SER A OG  1 
ATOM   3350  N N   . LEU A 1 505 ? 121.924 104.629 157.449 1.00 60.10  ? 505 LEU A N   1 
ATOM   3351  C CA  . LEU A 1 505 ? 120.858 105.632 157.432 1.00 58.43  ? 505 LEU A CA  1 
ATOM   3352  C C   . LEU A 1 505 ? 121.208 106.833 156.545 1.00 58.36  ? 505 LEU A C   1 
ATOM   3353  O O   . LEU A 1 505 ? 120.375 107.252 155.752 1.00 65.37  ? 505 LEU A O   1 
ATOM   3354  C CB  . LEU A 1 505 ? 120.581 106.051 158.882 1.00 66.73  ? 505 LEU A CB  1 
ATOM   3355  C CG  . LEU A 1 505 ? 119.574 107.190 159.079 1.00 61.78  ? 505 LEU A CG  1 
ATOM   3356  C CD1 . LEU A 1 505 ? 118.145 106.738 158.832 1.00 64.97  ? 505 LEU A CD1 1 
ATOM   3357  C CD2 . LEU A 1 505 ? 119.691 107.673 160.518 1.00 61.00  ? 505 LEU A CD2 1 
ATOM   3358  N N   . VAL A 1 506 ? 122.435 107.361 156.620 1.00 65.39  ? 506 VAL A N   1 
ATOM   3359  C CA  . VAL A 1 506 ? 122.896 108.447 155.738 1.00 58.30  ? 506 VAL A CA  1 
ATOM   3360  C C   . VAL A 1 506 ? 122.886 107.990 154.290 1.00 66.68  ? 506 VAL A C   1 
ATOM   3361  O O   . VAL A 1 506 ? 122.191 108.584 153.477 1.00 71.39  ? 506 VAL A O   1 
ATOM   3362  C CB  . VAL A 1 506 ? 124.297 108.963 156.096 1.00 55.72  ? 506 VAL A CB  1 
ATOM   3363  C CG1 . VAL A 1 506 ? 124.801 109.983 155.083 1.00 62.78  ? 506 VAL A CG1 1 
ATOM   3364  C CG2 . VAL A 1 506 ? 124.302 109.648 157.448 1.00 56.67  ? 506 VAL A CG2 1 
ATOM   3365  N N   . LEU A 1 507 ? 123.589 106.899 153.963 1.00 66.50  ? 507 LEU A N   1 
ATOM   3366  C CA  . LEU A 1 507 ? 123.556 106.318 152.620 1.00 53.00  ? 507 LEU A CA  1 
ATOM   3367  C C   . LEU A 1 507 ? 122.126 106.043 152.171 1.00 53.75  ? 507 LEU A C   1 
ATOM   3368  O O   . LEU A 1 507 ? 121.791 106.301 151.028 1.00 72.93  ? 507 LEU A O   1 
ATOM   3369  C CB  . LEU A 1 507 ? 124.354 105.011 152.599 1.00 61.02  ? 507 LEU A CB  1 
ATOM   3370  C CG  . LEU A 1 507 ? 125.829 105.226 152.262 1.00 64.60  ? 507 LEU A CG  1 
ATOM   3371  C CD1 . LEU A 1 507 ? 126.617 103.984 152.646 1.00 63.46  ? 507 LEU A CD1 1 
ATOM   3372  C CD2 . LEU A 1 507 ? 126.013 105.466 150.767 1.00 60.24  ? 507 LEU A CD2 1 
ATOM   3373  N N   . GLY A 1 508 ? 121.265 105.576 153.064 1.00 43.90  ? 508 GLY A N   1 
ATOM   3374  C CA  . GLY A 1 508 ? 119.870 105.329 152.770 1.00 50.38  ? 508 GLY A CA  1 
ATOM   3375  C C   . GLY A 1 508 ? 119.138 106.543 152.216 1.00 48.00  ? 508 GLY A C   1 
ATOM   3376  O O   . GLY A 1 508 ? 118.452 106.414 151.210 1.00 62.85  ? 508 GLY A O   1 
ATOM   3377  N N   . TRP A 1 509 ? 119.309 107.720 152.813 1.00 57.66  ? 509 TRP A N   1 
ATOM   3378  C CA  . TRP A 1 509 ? 118.709 108.959 152.315 1.00 50.25  ? 509 TRP A CA  1 
ATOM   3379  C C   . TRP A 1 509 ? 119.448 109.527 151.108 1.00 52.50  ? 509 TRP A C   1 
ATOM   3380  O O   . TRP A 1 509 ? 118.803 109.999 150.187 1.00 56.92  ? 509 TRP A O   1 
ATOM   3381  C CB  . TRP A 1 509 ? 118.609 109.990 153.441 1.00 60.27  ? 509 TRP A CB  1 
ATOM   3382  C CG  . TRP A 1 509 ? 117.508 109.714 154.416 1.00 58.87  ? 509 TRP A CG  1 
ATOM   3383  C CD1 . TRP A 1 509 ? 117.648 109.151 155.632 1.00 51.25  ? 509 TRP A CD1 1 
ATOM   3384  C CD2 . TRP A 1 509 ? 116.074 109.926 154.244 1.00 66.24  ? 509 TRP A CD2 1 
ATOM   3385  N NE1 . TRP A 1 509 ? 116.406 108.950 156.192 1.00 55.67  ? 509 TRP A NE1 1 
ATOM   3386  C CE2 . TRP A 1 509 ? 115.399 109.375 155.368 1.00 65.99  ? 509 TRP A CE2 1 
ATOM   3387  C CE3 . TRP A 1 509 ? 115.265 110.511 153.250 1.00 65.03  ? 509 TRP A CE3 1 
ATOM   3388  C CZ2 . TRP A 1 509 ? 114.002 109.343 155.475 1.00 62.51  ? 509 TRP A CZ2 1 
ATOM   3389  C CZ3 . TRP A 1 509 ? 113.857 110.490 153.350 1.00 69.21  ? 509 TRP A CZ3 1 
ATOM   3390  C CH2 . TRP A 1 509 ? 113.222 109.893 154.450 1.00 64.60  ? 509 TRP A CH2 1 
ATOM   3391  N N   . LEU A 1 510 ? 120.775 109.433 151.031 1.00 65.02  ? 510 LEU A N   1 
ATOM   3392  C CA  . LEU A 1 510 ? 121.517 109.832 149.828 1.00 60.58  ? 510 LEU A CA  1 
ATOM   3393  C C   . LEU A 1 510 ? 121.089 109.015 148.605 1.00 62.65  ? 510 LEU A C   1 
ATOM   3394  O O   . LEU A 1 510 ? 120.865 109.566 147.535 1.00 71.09  ? 510 LEU A O   1 
ATOM   3395  C CB  . LEU A 1 510 ? 123.031 109.703 150.060 1.00 57.51  ? 510 LEU A CB  1 
ATOM   3396  C CG  . LEU A 1 510 ? 123.610 110.598 151.163 1.00 61.49  ? 510 LEU A CG  1 
ATOM   3397  C CD1 . LEU A 1 510 ? 125.114 110.385 151.248 1.00 56.78  ? 510 LEU A CD1 1 
ATOM   3398  C CD2 . LEU A 1 510 ? 123.343 112.065 150.912 1.00 57.27  ? 510 LEU A CD2 1 
ATOM   3399  N N   . ASN A 1 511 ? 120.876 107.713 148.767 1.00 58.81  ? 511 ASN A N   1 
ATOM   3400  C CA  . ASN A 1 511 ? 120.340 106.823 147.746 1.00 50.23  ? 511 ASN A CA  1 
ATOM   3401  C C   . ASN A 1 511 ? 118.936 107.209 147.289 1.00 49.70  ? 511 ASN A C   1 
ATOM   3402  O O   . ASN A 1 511 ? 118.554 106.864 146.184 1.00 61.09  ? 511 ASN A O   1 
ATOM   3403  C CB  . ASN A 1 511 ? 120.324 105.397 148.296 1.00 47.42  ? 511 ASN A CB  1 
ATOM   3404  C CG  . ASN A 1 511 ? 121.679 104.748 148.369 1.00 55.68  ? 511 ASN A CG  1 
ATOM   3405  O OD1 . ASN A 1 511 ? 122.674 105.275 147.912 1.00 61.27  ? 511 ASN A OD1 1 
ATOM   3406  N ND2 . ASN A 1 511 ? 121.757 103.562 148.916 1.00 54.25  ? 511 ASN A ND2 1 
ATOM   3407  N N   . LEU A 1 512 ? 118.170 107.962 148.074 1.00 57.24  ? 512 LEU A N   1 
ATOM   3408  C CA  . LEU A 1 512 ? 116.855 108.462 147.677 1.00 54.61  ? 512 LEU A CA  1 
ATOM   3409  C C   . LEU A 1 512 ? 116.957 109.438 146.501 1.00 49.26  ? 512 LEU A C   1 
ATOM   3410  O O   . LEU A 1 512 ? 116.016 109.587 145.732 1.00 51.47  ? 512 LEU A O   1 
ATOM   3411  C CB  . LEU A 1 512 ? 116.203 109.132 148.894 1.00 54.57  ? 512 LEU A CB  1 
ATOM   3412  C CG  . LEU A 1 512 ? 114.684 109.260 148.811 1.00 55.95  ? 512 LEU A CG  1 
ATOM   3413  C CD1 . LEU A 1 512 ? 114.017 107.895 148.912 1.00 59.62  ? 512 LEU A CD1 1 
ATOM   3414  C CD2 . LEU A 1 512 ? 114.187 110.086 149.978 1.00 57.00  ? 512 LEU A CD2 1 
ATOM   3415  N N   . LEU A 1 513 ? 118.121 110.050 146.285 1.00 49.64  ? 513 LEU A N   1 
ATOM   3416  C CA  . LEU A 1 513 ? 118.376 110.890 145.120 1.00 53.10  ? 513 LEU A CA  1 
ATOM   3417  C C   . LEU A 1 513 ? 118.454 110.099 143.820 1.00 51.95  ? 513 LEU A C   1 
ATOM   3418  O O   . LEU A 1 513 ? 118.339 110.711 142.759 1.00 57.43  ? 513 LEU A O   1 
ATOM   3419  C CB  . LEU A 1 513 ? 119.657 111.709 145.317 1.00 55.32  ? 513 LEU A CB  1 
ATOM   3420  C CG  . LEU A 1 513 ? 119.571 112.685 146.487 1.00 49.68  ? 513 LEU A CG  1 
ATOM   3421  C CD1 . LEU A 1 513 ? 120.959 113.187 146.834 1.00 49.03  ? 513 LEU A CD1 1 
ATOM   3422  C CD2 . LEU A 1 513 ? 118.669 113.868 146.162 1.00 42.30  ? 513 LEU A CD2 1 
ATOM   3423  N N   . TYR A 1 514 ? 118.554 108.766 143.824 1.00 56.24  ? 514 TYR A N   1 
ATOM   3424  C CA  . TYR A 1 514 ? 118.450 107.977 142.594 1.00 41.60  ? 514 TYR A CA  1 
ATOM   3425  C C   . TYR A 1 514 ? 117.162 108.307 141.841 1.00 50.20  ? 514 TYR A C   1 
ATOM   3426  O O   . TYR A 1 514 ? 117.190 108.608 140.650 1.00 67.15  ? 514 TYR A O   1 
ATOM   3427  C CB  . TYR A 1 514 ? 118.522 106.483 142.919 1.00 43.06  ? 514 TYR A CB  1 
ATOM   3428  C CG  . TYR A 1 514 ? 118.154 105.581 141.759 1.00 37.37  ? 514 TYR A CG  1 
ATOM   3429  C CD1 . TYR A 1 514 ? 119.081 105.304 140.746 1.00 51.27  ? 514 TYR A CD1 1 
ATOM   3430  C CD2 . TYR A 1 514 ? 116.861 105.047 141.675 1.00 59.11  ? 514 TYR A CD2 1 
ATOM   3431  C CE1 . TYR A 1 514 ? 118.706 104.514 139.646 1.00 65.13  ? 514 TYR A CE1 1 
ATOM   3432  C CE2 . TYR A 1 514 ? 116.469 104.274 140.572 1.00 56.16  ? 514 TYR A CE2 1 
ATOM   3433  C CZ  . TYR A 1 514 ? 117.394 104.009 139.546 1.00 66.79  ? 514 TYR A CZ  1 
ATOM   3434  O OH  . TYR A 1 514 ? 117.028 103.271 138.469 1.00 67.85  ? 514 TYR A OH  1 
ATOM   3435  N N   . TYR A 1 515 ? 116.036 108.338 142.551 1.00 56.41  ? 515 TYR A N   1 
ATOM   3436  C CA  . TYR A 1 515 ? 114.704 108.458 141.965 1.00 46.15  ? 515 TYR A CA  1 
ATOM   3437  C C   . TYR A 1 515 ? 114.381 109.848 141.420 1.00 43.90  ? 515 TYR A C   1 
ATOM   3438  O O   . TYR A 1 515 ? 113.354 110.027 140.777 1.00 55.09  ? 515 TYR A O   1 
ATOM   3439  C CB  . TYR A 1 515 ? 113.669 107.989 142.984 1.00 42.25  ? 515 TYR A CB  1 
ATOM   3440  C CG  . TYR A 1 515 ? 113.889 106.565 143.445 1.00 46.11  ? 515 TYR A CG  1 
ATOM   3441  C CD1 . TYR A 1 515 ? 113.426 105.496 142.659 1.00 55.54  ? 515 TYR A CD1 1 
ATOM   3442  C CD2 . TYR A 1 515 ? 114.565 106.306 144.650 1.00 48.88  ? 515 TYR A CD2 1 
ATOM   3443  C CE1 . TYR A 1 515 ? 113.626 104.172 143.078 1.00 54.03  ? 515 TYR A CE1 1 
ATOM   3444  C CE2 . TYR A 1 515 ? 114.755 104.986 145.077 1.00 46.58  ? 515 TYR A CE2 1 
ATOM   3445  C CZ  . TYR A 1 515 ? 114.287 103.916 144.293 1.00 55.69  ? 515 TYR A CZ  1 
ATOM   3446  O OH  . TYR A 1 515 ? 114.475 102.647 144.717 1.00 65.29  ? 515 TYR A OH  1 
ATOM   3447  N N   . THR A 1 516 ? 115.266 110.834 141.574 1.00 53.88  ? 516 THR A N   1 
ATOM   3448  C CA  . THR A 1 516 ? 115.096 112.157 140.947 1.00 44.85  ? 516 THR A CA  1 
ATOM   3449  C C   . THR A 1 516 ? 115.029 112.086 139.421 1.00 57.44  ? 516 THR A C   1 
ATOM   3450  O O   . THR A 1 516 ? 114.444 112.977 138.815 1.00 65.38  ? 516 THR A O   1 
ATOM   3451  C CB  . THR A 1 516 ? 116.193 113.146 141.347 1.00 57.15  ? 516 THR A CB  1 
ATOM   3452  O OG1 . THR A 1 516 ? 117.473 112.670 141.017 1.00 68.73  ? 516 THR A OG1 1 
ATOM   3453  C CG2 . THR A 1 516 ? 116.162 113.502 142.820 1.00 52.56  ? 516 THR A CG2 1 
ATOM   3454  N N   . ARG A 1 517 ? 115.547 111.022 138.792 1.00 64.92  ? 517 ARG A N   1 
ATOM   3455  C CA  . ARG A 1 517 ? 115.468 110.753 137.343 1.00 59.58  ? 517 ARG A CA  1 
ATOM   3456  C C   . ARG A 1 517 ? 114.076 110.420 136.817 1.00 62.85  ? 517 ARG A C   1 
ATOM   3457  O O   . ARG A 1 517 ? 113.901 110.366 135.606 1.00 69.45  ? 517 ARG A O   1 
ATOM   3458  C CB  . ARG A 1 517 ? 116.478 109.665 136.947 1.00 54.02  ? 517 ARG A CB  1 
ATOM   3459  C CG  . ARG A 1 517 ? 116.097 108.255 137.427 1.00 48.83  ? 517 ARG A CG  1 
ATOM   3460  C CD  . ARG A 1 517 ? 117.242 107.258 137.275 1.00 49.93  ? 517 ARG A CD  1 
ATOM   3461  N NE  . ARG A 1 517 ? 118.393 107.663 138.097 1.00 57.68  ? 517 ARG A NE  1 
ATOM   3462  C CZ  . ARG A 1 517 ? 119.659 107.385 137.882 1.00 60.14  ? 517 ARG A CZ  1 
ATOM   3463  N NH1 . ARG A 1 517 ? 120.580 107.990 138.560 1.00 53.59  ? 517 ARG A NH1 1 
ATOM   3464  N NH2 . ARG A 1 517 ? 120.035 106.521 136.990 1.00 62.20  ? 517 ARG A NH2 1 
ATOM   3465  N N   . GLY A 1 518 ? 113.087 110.198 137.676 1.00 67.57  ? 518 GLY A N   1 
ATOM   3466  C CA  . GLY A 1 518 ? 111.734 109.861 137.240 1.00 64.26  ? 518 GLY A CA  1 
ATOM   3467  C C   . GLY A 1 518 ? 110.978 111.017 136.593 1.00 69.59  ? 518 GLY A C   1 
ATOM   3468  O O   . GLY A 1 518 ? 110.080 110.782 135.793 1.00 75.00  ? 518 GLY A O   1 
ATOM   3469  N N   . PHE A 1 519 ? 111.350 112.262 136.888 1.00 64.80  ? 519 PHE A N   1 
ATOM   3470  C CA  . PHE A 1 519 ? 110.762 113.466 136.303 1.00 70.20  ? 519 PHE A CA  1 
ATOM   3471  C C   . PHE A 1 519 ? 111.805 114.240 135.517 1.00 73.44  ? 519 PHE A C   1 
ATOM   3472  O O   . PHE A 1 519 ? 112.957 114.313 135.931 1.00 73.56  ? 519 PHE A O   1 
ATOM   3473  C CB  . PHE A 1 519 ? 110.167 114.364 137.392 1.00 75.42  ? 519 PHE A CB  1 
ATOM   3474  C CG  . PHE A 1 519 ? 109.143 113.706 138.287 1.00 78.05  ? 519 PHE A CG  1 
ATOM   3475  C CD1 . PHE A 1 519 ? 107.849 113.455 137.800 1.00 73.08  ? 519 PHE A CD1 1 
ATOM   3476  C CD2 . PHE A 1 519 ? 109.476 113.350 139.604 1.00 73.34  ? 519 PHE A CD2 1 
ATOM   3477  C CE1 . PHE A 1 519 ? 106.892 112.846 138.624 1.00 69.27  ? 519 PHE A CE1 1 
ATOM   3478  C CE2 . PHE A 1 519 ? 108.516 112.744 140.430 1.00 75.92  ? 519 PHE A CE2 1 
ATOM   3479  C CZ  . PHE A 1 519 ? 107.226 112.492 139.940 1.00 70.39  ? 519 PHE A CZ  1 
ATOM   3480  N N   . GLN A 1 520 ? 111.405 114.872 134.417 1.00 83.46  ? 520 GLN A N   1 
ATOM   3481  C CA  . GLN A 1 520 ? 112.320 115.641 133.580 1.00 80.69  ? 520 GLN A CA  1 
ATOM   3482  C C   . GLN A 1 520 ? 113.027 116.755 134.350 1.00 77.12  ? 520 GLN A C   1 
ATOM   3483  O O   . GLN A 1 520 ? 114.236 116.893 134.244 1.00 74.90  ? 520 GLN A O   1 
ATOM   3484  C CB  . GLN A 1 520 ? 111.561 116.192 132.366 1.00 80.75  ? 520 GLN A CB  1 
ATOM   3485  C CG  . GLN A 1 520 ? 112.518 116.906 131.400 1.00 81.23  ? 520 GLN A CG  1 
ATOM   3486  C CD  . GLN A 1 520 ? 111.956 117.143 130.003 1.00 85.42  ? 520 GLN A CD  1 
ATOM   3487  O OE1 . GLN A 1 520 ? 110.982 116.551 129.565 1.00 86.40  ? 520 GLN A OE1 1 
ATOM   3488  N NE2 . GLN A 1 520 ? 112.560 118.021 129.236 1.00 83.35  ? 520 GLN A NE2 1 
ATOM   3489  N N   . HIS A 1 521 ? 112.312 117.540 135.154 1.00 85.96  ? 521 HIS A N   1 
ATOM   3490  C CA  . HIS A 1 521 ? 112.896 118.723 135.785 1.00 88.21  ? 521 HIS A CA  1 
ATOM   3491  C C   . HIS A 1 521 ? 113.934 118.383 136.841 1.00 90.82  ? 521 HIS A C   1 
ATOM   3492  O O   . HIS A 1 521 ? 115.062 118.853 136.731 1.00 91.83  ? 521 HIS A O   1 
ATOM   3493  C CB  . HIS A 1 521 ? 111.793 119.668 136.267 1.00 86.83  ? 521 HIS A CB  1 
ATOM   3494  C CG  . HIS A 1 521 ? 111.144 120.317 135.073 1.00 94.75  ? 521 HIS A CG  1 
ATOM   3495  N ND1 . HIS A 1 521 ? 111.735 121.313 134.295 1.00 89.69  ? 521 HIS A ND1 1 
ATOM   3496  C CD2 . HIS A 1 521 ? 109.993 119.908 134.470 1.00 94.10  ? 521 HIS A CD2 1 
ATOM   3497  C CE1 . HIS A 1 521 ? 110.919 121.490 133.245 1.00 90.45  ? 521 HIS A CE1 1 
ATOM   3498  N NE2 . HIS A 1 521 ? 109.865 120.665 133.327 1.00 91.76  ? 521 HIS A NE2 1 
ATOM   3499  N N   . THR A 1 522 ? 113.631 117.528 137.814 1.00 82.26  ? 522 THR A N   1 
ATOM   3500  C CA  . THR A 1 522 ? 114.634 117.044 138.777 1.00 73.99  ? 522 THR A CA  1 
ATOM   3501  C C   . THR A 1 522 ? 115.687 116.139 138.127 1.00 82.26  ? 522 THR A C   1 
ATOM   3502  O O   . THR A 1 522 ? 116.854 116.208 138.504 1.00 71.79  ? 522 THR A O   1 
ATOM   3503  C CB  . THR A 1 522 ? 113.966 116.310 139.946 1.00 65.54  ? 522 THR A CB  1 
ATOM   3504  O OG1 . THR A 1 522 ? 113.109 115.289 139.500 1.00 76.86  ? 522 THR A OG1 1 
ATOM   3505  C CG2 . THR A 1 522 ? 113.124 117.256 140.789 1.00 64.34  ? 522 THR A CG2 1 
ATOM   3506  N N   . GLY A 1 523 ? 115.309 115.333 137.130 1.00 83.56  ? 523 GLY A N   1 
ATOM   3507  C CA  . GLY A 1 523 ? 116.161 114.324 136.496 1.00 68.09  ? 523 GLY A CA  1 
ATOM   3508  C C   . GLY A 1 523 ? 117.200 114.885 135.540 1.00 73.13  ? 523 GLY A C   1 
ATOM   3509  O O   . GLY A 1 523 ? 118.312 114.379 135.484 1.00 76.54  ? 523 GLY A O   1 
ATOM   3510  N N   . ILE A 1 524 ? 116.883 115.975 134.847 1.00 79.24  ? 524 ILE A N   1 
ATOM   3511  C CA  . ILE A 1 524 ? 117.859 116.768 134.100 1.00 80.83  ? 524 ILE A CA  1 
ATOM   3512  C C   . ILE A 1 524 ? 118.763 117.568 135.043 1.00 85.77  ? 524 ILE A C   1 
ATOM   3513  O O   . ILE A 1 524 ? 119.956 117.668 134.784 1.00 82.02  ? 524 ILE A O   1 
ATOM   3514  C CB  . ILE A 1 524 ? 117.127 117.661 133.077 1.00 83.52  ? 524 ILE A CB  1 
ATOM   3515  C CG1 . ILE A 1 524 ? 116.659 116.753 131.925 1.00 77.39  ? 524 ILE A CG1 1 
ATOM   3516  C CG2 . ILE A 1 524 ? 118.003 118.804 132.570 1.00 84.18  ? 524 ILE A CG2 1 
ATOM   3517  C CD1 . ILE A 1 524 ? 115.911 117.480 130.814 1.00 78.40  ? 524 ILE A CD1 1 
ATOM   3518  N N   . TYR A 1 525 ? 118.264 118.097 136.163 1.00 83.84  ? 525 TYR A N   1 
ATOM   3519  C CA  . TYR A 1 525 ? 119.126 118.840 137.077 1.00 83.40  ? 525 TYR A CA  1 
ATOM   3520  C C   . TYR A 1 525 ? 120.153 117.948 137.777 1.00 82.40  ? 525 TYR A C   1 
ATOM   3521  O O   . TYR A 1 525 ? 121.327 118.299 137.835 1.00 81.65  ? 525 TYR A O   1 
ATOM   3522  C CB  . TYR A 1 525 ? 118.302 119.628 138.084 1.00 83.87  ? 525 TYR A CB  1 
ATOM   3523  C CG  . TYR A 1 525 ? 119.133 120.679 138.782 1.00 81.03  ? 525 TYR A CG  1 
ATOM   3524  C CD1 . TYR A 1 525 ? 119.592 121.786 138.049 1.00 79.24  ? 525 TYR A CD1 1 
ATOM   3525  C CD2 . TYR A 1 525 ? 119.507 120.516 140.128 1.00 80.51  ? 525 TYR A CD2 1 
ATOM   3526  C CE1 . TYR A 1 525 ? 120.431 122.735 138.657 1.00 83.94  ? 525 TYR A CE1 1 
ATOM   3527  C CE2 . TYR A 1 525 ? 120.332 121.475 140.743 1.00 83.04  ? 525 TYR A CE2 1 
ATOM   3528  C CZ  . TYR A 1 525 ? 120.797 122.585 140.006 1.00 82.24  ? 525 TYR A CZ  1 
ATOM   3529  O OH  . TYR A 1 525 ? 121.606 123.503 140.583 1.00 74.13  ? 525 TYR A OH  1 
ATOM   3530  N N   . SER A 1 526 ? 119.764 116.743 138.197 1.00 81.33  ? 526 SER A N   1 
ATOM   3531  C CA  . SER A 1 526 ? 120.707 115.728 138.682 1.00 82.45  ? 526 SER A CA  1 
ATOM   3532  C C   . SER A 1 526 ? 121.822 115.392 137.684 1.00 81.27  ? 526 SER A C   1 
ATOM   3533  O O   . SER A 1 526 ? 122.876 114.911 138.080 1.00 83.05  ? 526 SER A O   1 
ATOM   3534  C CB  . SER A 1 526 ? 119.951 114.454 139.062 1.00 85.48  ? 526 SER A CB  1 
ATOM   3535  O OG  . SER A 1 526 ? 119.125 114.716 140.177 1.00 82.43  ? 526 SER A OG  1 
ATOM   3536  N N   . VAL A 1 527 ? 121.625 115.683 136.397 1.00 88.33  ? 527 VAL A N   1 
ATOM   3537  C CA  . VAL A 1 527 ? 122.612 115.547 135.320 1.00 87.86  ? 527 VAL A CA  1 
ATOM   3538  C C   . VAL A 1 527 ? 123.382 116.847 135.043 1.00 90.09  ? 527 VAL A C   1 
ATOM   3539  O O   . VAL A 1 527 ? 124.560 116.794 134.704 1.00 89.88  ? 527 VAL A O   1 
ATOM   3540  C CB  . VAL A 1 527 ? 121.883 115.039 134.075 1.00 85.09  ? 527 VAL A CB  1 
ATOM   3541  C CG1 . VAL A 1 527 ? 122.740 115.075 132.827 1.00 86.41  ? 527 VAL A CG1 1 
ATOM   3542  C CG2 . VAL A 1 527 ? 121.436 113.592 134.260 1.00 85.01  ? 527 VAL A CG2 1 
ATOM   3543  N N   . MET A 1 528 ? 122.767 118.021 135.207 1.00 97.92  ? 528 MET A N   1 
ATOM   3544  C CA  . MET A 1 528 ? 123.461 119.315 135.114 1.00 97.18  ? 528 MET A CA  1 
ATOM   3545  C C   . MET A 1 528 ? 124.536 119.480 136.189 1.00 94.61  ? 528 MET A C   1 
ATOM   3546  O O   . MET A 1 528 ? 125.623 119.966 135.887 1.00 92.84  ? 528 MET A O   1 
ATOM   3547  C CB  . MET A 1 528 ? 122.474 120.476 135.264 1.00 96.35  ? 528 MET A CB  1 
ATOM   3548  C CG  . MET A 1 528 ? 121.553 120.663 134.060 1.00 99.60  ? 528 MET A CG  1 
ATOM   3549  S SD  . MET A 1 528 ? 120.249 121.900 134.305 1.00 108.41 ? 528 MET A SD  1 
ATOM   3550  C CE  . MET A 1 528 ? 121.240 123.375 134.639 1.00 94.89  ? 528 MET A CE  1 
ATOM   3551  N N   . ILE A 1 529 ? 124.195 119.088 137.415 1.00 95.56  ? 529 ILE A N   1 
ATOM   3552  C CA  . ILE A 1 529 ? 124.995 119.328 138.604 1.00 92.51  ? 529 ILE A CA  1 
ATOM   3553  C C   . ILE A 1 529 ? 126.222 118.401 138.674 1.00 92.75  ? 529 ILE A C   1 
ATOM   3554  O O   . ILE A 1 529 ? 127.339 118.899 138.772 1.00 91.37  ? 529 ILE A O   1 
ATOM   3555  C CB  . ILE A 1 529 ? 124.046 119.334 139.830 1.00 91.99  ? 529 ILE A CB  1 
ATOM   3556  C CG1 . ILE A 1 529 ? 124.656 120.090 141.021 1.00 90.78  ? 529 ILE A CG1 1 
ATOM   3557  C CG2 . ILE A 1 529 ? 123.579 117.939 140.269 1.00 90.26  ? 529 ILE A CG2 1 
ATOM   3558  C CD1 . ILE A 1 529 ? 123.615 120.664 141.976 1.00 89.15  ? 529 ILE A CD1 1 
ATOM   3559  N N   . GLN A 1 530 ? 126.070 117.075 138.586 1.00 97.92  ? 530 GLN A N   1 
ATOM   3560  C CA  . GLN A 1 530 ? 127.202 116.140 138.694 1.00 96.49  ? 530 GLN A CA  1 
ATOM   3561  C C   . GLN A 1 530 ? 128.050 116.135 137.414 1.00 94.61  ? 530 GLN A C   1 
ATOM   3562  O O   . GLN A 1 530 ? 127.515 115.920 136.330 1.00 94.03  ? 530 GLN A O   1 
ATOM   3563  C CB  . GLN A 1 530 ? 126.707 114.742 139.113 1.00 93.24  ? 530 GLN A CB  1 
ATOM   3564  C CG  . GLN A 1 530 ? 125.994 113.936 138.017 1.00 94.46  ? 530 GLN A CG  1 
ATOM   3565  C CD  . GLN A 1 530 ? 125.191 112.737 138.530 1.00 98.38  ? 530 GLN A CD  1 
ATOM   3566  O OE1 . GLN A 1 530 ? 125.004 112.508 139.720 1.00 99.03  ? 530 GLN A OE1 1 
ATOM   3567  N NE2 . GLN A 1 530 ? 124.726 111.882 137.652 1.00 97.52  ? 530 GLN A NE2 1 
ATOM   3568  N N   . LYS A 1 531 ? 129.364 116.396 137.514 1.00 91.25  ? 531 LYS A N   1 
ATOM   3569  C CA  . LYS A 1 531 ? 130.251 116.571 136.343 1.00 95.79  ? 531 LYS A CA  1 
ATOM   3570  C C   . LYS A 1 531 ? 131.750 116.384 136.639 1.00 99.98  ? 531 LYS A C   1 
ATOM   3571  O O   . LYS A 1 531 ? 132.126 115.887 137.700 1.00 92.48  ? 531 LYS A O   1 
ATOM   3572  C CB  . LYS A 1 531 ? 129.916 117.923 135.664 1.00 90.62  ? 531 LYS A CB  1 
ATOM   3573  C CG  . LYS A 1 531 ? 130.263 119.200 136.450 1.00 84.08  ? 531 LYS A CG  1 
ATOM   3574  C CD  . LYS A 1 531 ? 129.414 120.400 135.992 1.00 88.92  ? 531 LYS A CD  1 
ATOM   3575  C CE  . LYS A 1 531 ? 129.507 120.648 134.476 1.00 90.70  ? 531 LYS A CE  1 
ATOM   3576  N NZ  . LYS A 1 531 ? 128.498 121.625 133.996 1.00 83.80  ? 531 LYS A NZ  1 
ATOM   3577  N N   . VAL A 1 532 ? 132.594 116.838 135.701 1.00 108.16 ? 532 VAL A N   1 
ATOM   3578  C CA  . VAL A 1 532 ? 134.084 116.874 135.684 1.00 99.51  ? 532 VAL A CA  1 
ATOM   3579  C C   . VAL A 1 532 ? 134.730 117.408 136.974 1.00 95.06  ? 532 VAL A C   1 
ATOM   3580  O O   . VAL A 1 532 ? 135.877 117.092 137.277 1.00 96.47  ? 532 VAL A O   1 
ATOM   3581  C CB  . VAL A 1 532 ? 134.530 117.721 134.467 1.00 97.06  ? 532 VAL A CB  1 
ATOM   3582  C CG1 . VAL A 1 532 ? 136.003 118.121 134.460 1.00 93.95  ? 532 VAL A CG1 1 
ATOM   3583  C CG2 . VAL A 1 532 ? 134.259 116.963 133.160 1.00 96.78  ? 532 VAL A CG2 1 
ATOM   3584  N N   . ILE A 1 533 ? 133.985 118.140 137.794 1.00 90.50  ? 533 ILE A N   1 
ATOM   3585  C CA  . ILE A 1 533 ? 134.395 118.561 139.137 1.00 88.90  ? 533 ILE A CA  1 
ATOM   3586  C C   . ILE A 1 533 ? 134.832 117.365 140.004 1.00 90.60  ? 533 ILE A C   1 
ATOM   3587  O O   . ILE A 1 533 ? 135.812 117.478 140.733 1.00 93.35  ? 533 ILE A O   1 
ATOM   3588  C CB  . ILE A 1 533 ? 133.246 119.386 139.756 1.00 89.22  ? 533 ILE A CB  1 
ATOM   3589  C CG1 . ILE A 1 533 ? 133.080 120.698 138.957 1.00 92.45  ? 533 ILE A CG1 1 
ATOM   3590  C CG2 . ILE A 1 533 ? 133.486 119.697 141.239 1.00 90.34  ? 533 ILE A CG2 1 
ATOM   3591  C CD1 . ILE A 1 533 ? 131.755 121.412 139.198 1.00 92.90  ? 533 ILE A CD1 1 
ATOM   3592  N N   . LEU A 1 534 ? 134.206 116.186 139.879 1.00 92.52  ? 534 LEU A N   1 
ATOM   3593  C CA  . LEU A 1 534 ? 134.611 114.993 140.638 1.00 85.01  ? 534 LEU A CA  1 
ATOM   3594  C C   . LEU A 1 534 ? 136.004 114.464 140.259 1.00 84.45  ? 534 LEU A C   1 
ATOM   3595  O O   . LEU A 1 534 ? 136.698 113.902 141.105 1.00 84.27  ? 534 LEU A O   1 
ATOM   3596  C CB  . LEU A 1 534 ? 133.563 113.876 140.465 1.00 90.88  ? 534 LEU A CB  1 
ATOM   3597  C CG  . LEU A 1 534 ? 132.163 114.186 141.025 1.00 93.01  ? 534 LEU A CG  1 
ATOM   3598  C CD1 . LEU A 1 534 ? 131.225 113.025 140.714 1.00 86.83  ? 534 LEU A CD1 1 
ATOM   3599  C CD2 . LEU A 1 534 ? 132.165 114.399 142.535 1.00 88.11  ? 534 LEU A CD2 1 
ATOM   3600  N N   . ARG A 1 535 ? 136.432 114.745 139.012 1.00 95.69  ? 535 ARG A N   1 
ATOM   3601  C CA  . ARG A 1 535 ? 137.763 114.315 138.483 1.00 96.73  ? 535 ARG A CA  1 
ATOM   3602  C C   . ARG A 1 535 ? 138.868 115.232 138.995 1.00 94.38  ? 535 ARG A C   1 
ATOM   3603  O O   . ARG A 1 535 ? 139.921 114.713 139.413 1.00 91.59  ? 535 ARG A O   1 
ATOM   3604  C CB  . ARG A 1 535 ? 137.759 114.417 136.942 1.00 96.33  ? 535 ARG A CB  1 
ATOM   3605  C CG  . ARG A 1 535 ? 139.069 113.996 136.253 1.00 91.80  ? 535 ARG A CG  1 
ATOM   3606  C CD  . ARG A 1 535 ? 139.120 114.500 134.799 1.00 93.45  ? 535 ARG A CD  1 
ATOM   3607  N NE  . ARG A 1 535 ? 139.340 115.957 134.745 1.00 96.57  ? 535 ARG A NE  1 
ATOM   3608  C CZ  . ARG A 1 535 ? 139.382 116.679 133.632 1.00 96.76  ? 535 ARG A CZ  1 
ATOM   3609  N NH1 . ARG A 1 535 ? 139.587 117.983 133.699 1.00 92.71  ? 535 ARG A NH1 1 
ATOM   3610  N NH2 . ARG A 1 535 ? 139.215 116.097 132.457 1.00 93.94  ? 535 ARG A NH2 1 
ATOM   3611  N N   . ASP A 1 536 ? 138.632 116.540 138.963 1.00 92.54  ? 536 ASP A N   1 
ATOM   3612  C CA  . ASP A 1 536 ? 139.640 117.536 139.326 1.00 86.00  ? 536 ASP A CA  1 
ATOM   3613  C C   . ASP A 1 536 ? 139.731 117.830 140.817 1.00 86.46  ? 536 ASP A C   1 
ATOM   3614  O O   . ASP A 1 536 ? 140.827 118.072 141.311 1.00 93.57  ? 536 ASP A O   1 
ATOM   3615  C CB  . ASP A 1 536 ? 139.405 118.821 138.537 1.00 89.61  ? 536 ASP A CB  1 
ATOM   3616  C CG  . ASP A 1 536 ? 139.744 118.656 137.056 1.00 94.75  ? 536 ASP A CG  1 
ATOM   3617  O OD1 . ASP A 1 536 ? 140.392 117.652 136.679 1.00 97.83  ? 536 ASP A OD1 1 
ATOM   3618  O OD2 . ASP A 1 536 ? 139.373 119.521 136.242 1.00 94.88  ? 536 ASP A OD2 1 
ATOM   3619  N N   . LEU A 1 537 ? 138.646 117.730 141.584 1.00 85.98  ? 537 LEU A N   1 
ATOM   3620  C CA  . LEU A 1 537 ? 138.756 117.839 143.039 1.00 86.17  ? 537 LEU A CA  1 
ATOM   3621  C C   . LEU A 1 537 ? 139.612 116.727 143.648 1.00 86.73  ? 537 LEU A C   1 
ATOM   3622  O O   . LEU A 1 537 ? 140.380 116.991 144.563 1.00 91.76  ? 537 LEU A O   1 
ATOM   3623  C CB  . LEU A 1 537 ? 137.373 117.873 143.690 1.00 88.25  ? 537 LEU A CB  1 
ATOM   3624  C CG  . LEU A 1 537 ? 136.607 119.185 143.473 1.00 90.83  ? 537 LEU A CG  1 
ATOM   3625  C CD1 . LEU A 1 537 ? 135.318 119.081 144.268 1.00 87.14  ? 537 LEU A CD1 1 
ATOM   3626  C CD2 . LEU A 1 537 ? 137.359 120.418 143.971 1.00 88.73  ? 537 LEU A CD2 1 
ATOM   3627  N N   . LEU A 1 538 ? 139.579 115.513 143.102 1.00 83.58  ? 538 LEU A N   1 
ATOM   3628  C CA  . LEU A 1 538 ? 140.466 114.423 143.509 1.00 88.19  ? 538 LEU A CA  1 
ATOM   3629  C C   . LEU A 1 538 ? 141.945 114.688 143.158 1.00 84.60  ? 538 LEU A C   1 
ATOM   3630  O O   . LEU A 1 538 ? 142.841 114.095 143.753 1.00 84.06  ? 538 LEU A O   1 
ATOM   3631  C CB  . LEU A 1 538 ? 139.917 113.123 142.890 1.00 89.66  ? 538 LEU A CB  1 
ATOM   3632  C CG  . LEU A 1 538 ? 140.625 111.829 143.312 1.00 89.64  ? 538 LEU A CG  1 
ATOM   3633  C CD1 . LEU A 1 538 ? 140.548 111.596 144.817 1.00 84.51  ? 538 LEU A CD1 1 
ATOM   3634  C CD2 . LEU A 1 538 ? 139.972 110.638 142.620 1.00 87.53  ? 538 LEU A CD2 1 
ATOM   3635  N N   . ARG A 1 539 ? 142.193 115.649 142.247 1.00 79.33  ? 539 ARG A N   1 
ATOM   3636  C CA  . ARG A 1 539 ? 143.594 116.059 141.901 1.00 76.40  ? 539 ARG A CA  1 
ATOM   3637  C C   . ARG A 1 539 ? 143.997 117.199 142.851 1.00 79.54  ? 539 ARG A C   1 
ATOM   3638  O O   . ARG A 1 539 ? 145.120 117.135 143.389 1.00 84.10  ? 539 ARG A O   1 
ATOM   3639  C CB  . ARG A 1 539 ? 143.725 116.351 140.398 1.00 78.41  ? 539 ARG A CB  1 
ATOM   3640  C CG  . ARG A 1 539 ? 143.375 115.120 139.550 1.00 75.92  ? 539 ARG A CG  1 
ATOM   3641  C CD  . ARG A 1 539 ? 143.905 115.207 138.123 1.00 76.05  ? 539 ARG A CD  1 
ATOM   3642  N NE  . ARG A 1 539 ? 143.134 116.087 137.221 1.00 79.62  ? 539 ARG A NE  1 
ATOM   3643  C CZ  . ARG A 1 539 ? 143.472 116.367 135.968 1.00 78.59  ? 539 ARG A CZ  1 
ATOM   3644  N NH1 . ARG A 1 539 ? 142.712 117.170 135.242 1.00 76.30  ? 539 ARG A NH1 1 
ATOM   3645  N NH2 . ARG A 1 539 ? 144.568 115.848 135.444 1.00 79.19  ? 539 ARG A NH2 1 
ATOM   3646  N N   . PHE A 1 540 ? 143.126 118.188 143.059 1.00 81.83  ? 540 PHE A N   1 
ATOM   3647  C CA  . PHE A 1 540 ? 143.327 119.289 144.010 1.00 74.26  ? 540 PHE A CA  1 
ATOM   3648  C C   . PHE A 1 540 ? 143.522 118.784 145.438 1.00 76.00  ? 540 PHE A C   1 
ATOM   3649  O O   . PHE A 1 540 ? 144.350 119.325 146.158 1.00 74.84  ? 540 PHE A O   1 
ATOM   3650  C CB  . PHE A 1 540 ? 142.131 120.254 143.928 1.00 76.38  ? 540 PHE A CB  1 
ATOM   3651  C CG  . PHE A 1 540 ? 141.756 120.978 145.212 1.00 91.80  ? 540 PHE A CG  1 
ATOM   3652  C CD1 . PHE A 1 540 ? 142.481 122.106 145.641 1.00 85.68  ? 540 PHE A CD1 1 
ATOM   3653  C CD2 . PHE A 1 540 ? 140.665 120.520 145.980 1.00 87.27  ? 540 PHE A CD2 1 
ATOM   3654  C CE1 . PHE A 1 540 ? 142.123 122.756 146.840 1.00 78.52  ? 540 PHE A CE1 1 
ATOM   3655  C CE2 . PHE A 1 540 ? 140.318 121.160 147.175 1.00 79.01  ? 540 PHE A CE2 1 
ATOM   3656  C CZ  . PHE A 1 540 ? 141.058 122.282 147.605 1.00 80.15  ? 540 PHE A CZ  1 
ATOM   3657  N N   . LEU A 1 541 ? 142.829 117.716 145.826 1.00 74.81  ? 541 LEU A N   1 
ATOM   3658  C CA  . LEU A 1 541 ? 142.918 117.126 147.155 1.00 72.57  ? 541 LEU A CA  1 
ATOM   3659  C C   . LEU A 1 541 ? 144.343 116.662 147.491 1.00 67.71  ? 541 LEU A C   1 
ATOM   3660  O O   . LEU A 1 541 ? 144.771 116.810 148.624 1.00 75.75  ? 541 LEU A O   1 
ATOM   3661  C CB  . LEU A 1 541 ? 141.890 115.994 147.249 1.00 71.75  ? 541 LEU A CB  1 
ATOM   3662  C CG  . LEU A 1 541 ? 141.768 115.364 148.638 1.00 75.82  ? 541 LEU A CG  1 
ATOM   3663  C CD1 . LEU A 1 541 ? 141.182 116.347 149.647 1.00 72.14  ? 541 LEU A CD1 1 
ATOM   3664  C CD2 . LEU A 1 541 ? 140.869 114.140 148.564 1.00 76.85  ? 541 LEU A CD2 1 
ATOM   3665  N N   . LEU A 1 542 ? 145.121 116.177 146.523 1.00 56.79  ? 542 LEU A N   1 
ATOM   3666  C CA  . LEU A 1 542 ? 146.530 115.849 146.745 1.00 60.41  ? 542 LEU A CA  1 
ATOM   3667  C C   . LEU A 1 542 ? 147.359 117.092 147.099 1.00 61.80  ? 542 LEU A C   1 
ATOM   3668  O O   . LEU A 1 542 ? 148.143 117.068 148.042 1.00 64.97  ? 542 LEU A O   1 
ATOM   3669  C CB  . LEU A 1 542 ? 147.058 115.129 145.490 1.00 71.20  ? 542 LEU A CB  1 
ATOM   3670  C CG  . LEU A 1 542 ? 148.533 114.705 145.557 1.00 73.14  ? 542 LEU A CG  1 
ATOM   3671  C CD1 . LEU A 1 542 ? 148.806 113.690 146.665 1.00 67.64  ? 542 LEU A CD1 1 
ATOM   3672  C CD2 . LEU A 1 542 ? 148.924 114.068 144.233 1.00 60.03  ? 542 LEU A CD2 1 
ATOM   3673  N N   . VAL A 1 543 ? 147.154 118.205 146.392 1.00 66.63  ? 543 VAL A N   1 
ATOM   3674  C CA  . VAL A 1 543 ? 147.840 119.478 146.669 1.00 67.55  ? 543 VAL A CA  1 
ATOM   3675  C C   . VAL A 1 543 ? 147.402 120.058 148.014 1.00 62.46  ? 543 VAL A C   1 
ATOM   3676  O O   . VAL A 1 543 ? 148.237 120.419 148.836 1.00 59.96  ? 543 VAL A O   1 
ATOM   3677  C CB  . VAL A 1 543 ? 147.626 120.506 145.544 1.00 63.58  ? 543 VAL A CB  1 
ATOM   3678  C CG1 . VAL A 1 543 ? 148.565 121.698 145.711 1.00 55.67  ? 543 VAL A CG1 1 
ATOM   3679  C CG2 . VAL A 1 543 ? 147.894 119.911 144.161 1.00 61.64  ? 543 VAL A CG2 1 
ATOM   3680  N N   . TYR A 1 544 ? 146.095 120.073 148.285 1.00 68.60  ? 544 TYR A N   1 
ATOM   3681  C CA  . TYR A 1 544 ? 145.534 120.543 149.541 1.00 61.87  ? 544 TYR A CA  1 
ATOM   3682  C C   . TYR A 1 544 ? 145.980 119.715 150.752 1.00 61.11  ? 544 TYR A C   1 
ATOM   3683  O O   . TYR A 1 544 ? 146.277 120.291 151.792 1.00 65.28  ? 544 TYR A O   1 
ATOM   3684  C CB  . TYR A 1 544 ? 144.003 120.533 149.479 1.00 69.45  ? 544 TYR A CB  1 
ATOM   3685  C CG  . TYR A 1 544 ? 143.341 120.984 150.756 1.00 76.72  ? 544 TYR A CG  1 
ATOM   3686  C CD1 . TYR A 1 544 ? 143.061 120.085 151.773 1.00 75.45  ? 544 TYR A CD1 1 
ATOM   3687  C CD2 . TYR A 1 544 ? 143.012 122.314 150.960 1.00 72.08  ? 544 TYR A CD2 1 
ATOM   3688  C CE1 . TYR A 1 544 ? 142.460 120.493 152.952 1.00 74.41  ? 544 TYR A CE1 1 
ATOM   3689  C CE2 . TYR A 1 544 ? 142.412 122.738 152.134 1.00 66.53  ? 544 TYR A CE2 1 
ATOM   3690  C CZ  . TYR A 1 544 ? 142.134 121.825 153.134 1.00 75.48  ? 544 TYR A CZ  1 
ATOM   3691  O OH  . TYR A 1 544 ? 141.543 122.236 154.293 1.00 78.59  ? 544 TYR A OH  1 
ATOM   3692  N N   . LEU A 1 545 ? 146.079 118.387 150.648 1.00 60.97  ? 545 LEU A N   1 
ATOM   3693  C CA  . LEU A 1 545 ? 146.545 117.531 151.745 1.00 58.63  ? 545 LEU A CA  1 
ATOM   3694  C C   . LEU A 1 545 ? 148.060 117.575 151.973 1.00 54.60  ? 545 LEU A C   1 
ATOM   3695  O O   . LEU A 1 545 ? 148.486 117.421 153.112 1.00 55.11  ? 545 LEU A O   1 
ATOM   3696  C CB  . LEU A 1 545 ? 146.084 116.085 151.526 1.00 56.50  ? 545 LEU A CB  1 
ATOM   3697  C CG  . LEU A 1 545 ? 144.572 115.861 151.668 1.00 65.75  ? 545 LEU A CG  1 
ATOM   3698  C CD1 . LEU A 1 545 ? 144.272 114.397 151.386 1.00 63.24  ? 545 LEU A CD1 1 
ATOM   3699  C CD2 . LEU A 1 545 ? 144.046 116.196 153.057 1.00 66.35  ? 545 LEU A CD2 1 
ATOM   3700  N N   . VAL A 1 546 ? 148.893 117.827 150.962 1.00 65.29  ? 546 VAL A N   1 
ATOM   3701  C CA  . VAL A 1 546 ? 150.325 118.088 151.198 1.00 61.16  ? 546 VAL A CA  1 
ATOM   3702  C C   . VAL A 1 546 ? 150.530 119.432 151.891 1.00 68.30  ? 546 VAL A C   1 
ATOM   3703  O O   . VAL A 1 546 ? 151.338 119.513 152.813 1.00 65.70  ? 546 VAL A O   1 
ATOM   3704  C CB  . VAL A 1 546 ? 151.151 117.987 149.906 1.00 61.18  ? 546 VAL A CB  1 
ATOM   3705  C CG1 . VAL A 1 546 ? 152.596 118.433 150.124 1.00 57.53  ? 546 VAL A CG1 1 
ATOM   3706  C CG2 . VAL A 1 546 ? 151.200 116.538 149.418 1.00 65.16  ? 546 VAL A CG2 1 
ATOM   3707  N N   . PHE A 1 547 ? 149.769 120.472 151.532 1.00 77.33  ? 547 PHE A N   1 
ATOM   3708  C CA  . PHE A 1 547 ? 149.749 121.719 152.296 1.00 66.38  ? 547 PHE A CA  1 
ATOM   3709  C C   . PHE A 1 547 ? 149.273 121.463 153.727 1.00 68.87  ? 547 PHE A C   1 
ATOM   3710  O O   . PHE A 1 547 ? 149.991 121.762 154.675 1.00 77.65  ? 547 PHE A O   1 
ATOM   3711  C CB  . PHE A 1 547 ? 148.835 122.762 151.636 1.00 68.07  ? 547 PHE A CB  1 
ATOM   3712  C CG  . PHE A 1 547 ? 149.311 123.475 150.384 1.00 74.86  ? 547 PHE A CG  1 
ATOM   3713  C CD1 . PHE A 1 547 ? 150.447 123.075 149.659 1.00 71.03  ? 547 PHE A CD1 1 
ATOM   3714  C CD2 . PHE A 1 547 ? 148.580 124.596 149.949 1.00 75.46  ? 547 PHE A CD2 1 
ATOM   3715  C CE1 . PHE A 1 547 ? 150.865 123.807 148.537 1.00 73.22  ? 547 PHE A CE1 1 
ATOM   3716  C CE2 . PHE A 1 547 ? 148.990 125.312 148.816 1.00 77.28  ? 547 PHE A CE2 1 
ATOM   3717  C CZ  . PHE A 1 547 ? 150.134 124.927 148.111 1.00 70.36  ? 547 PHE A CZ  1 
ATOM   3718  N N   . LEU A 1 548 ? 148.090 120.881 153.906 1.00 62.91  ? 548 LEU A N   1 
ATOM   3719  C CA  . LEU A 1 548 ? 147.476 120.701 155.216 1.00 60.98  ? 548 LEU A CA  1 
ATOM   3720  C C   . LEU A 1 548 ? 148.344 119.867 156.162 1.00 64.14  ? 548 LEU A C   1 
ATOM   3721  O O   . LEU A 1 548 ? 148.608 120.305 157.274 1.00 72.05  ? 548 LEU A O   1 
ATOM   3722  C CB  . LEU A 1 548 ? 146.068 120.113 155.022 1.00 65.40  ? 548 LEU A CB  1 
ATOM   3723  C CG  . LEU A 1 548 ? 145.286 119.903 156.323 1.00 58.48  ? 548 LEU A CG  1 
ATOM   3724  C CD1 . LEU A 1 548 ? 145.005 121.224 157.011 1.00 64.99  ? 548 LEU A CD1 1 
ATOM   3725  C CD2 . LEU A 1 548 ? 143.954 119.237 156.029 1.00 61.73  ? 548 LEU A CD2 1 
ATOM   3726  N N   . PHE A 1 549 ? 148.841 118.703 155.743 1.00 67.92  ? 549 PHE A N   1 
ATOM   3727  C CA  . PHE A 1 549 ? 149.734 117.908 156.584 1.00 63.42  ? 549 PHE A CA  1 
ATOM   3728  C C   . PHE A 1 549 ? 151.091 118.593 156.795 1.00 67.26  ? 549 PHE A C   1 
ATOM   3729  O O   . PHE A 1 549 ? 151.575 118.629 157.920 1.00 63.99  ? 549 PHE A O   1 
ATOM   3730  C CB  . PHE A 1 549 ? 149.900 116.511 155.983 1.00 67.57  ? 549 PHE A CB  1 
ATOM   3731  C CG  . PHE A 1 549 ? 150.790 115.601 156.803 1.00 76.26  ? 549 PHE A CG  1 
ATOM   3732  C CD1 . PHE A 1 549 ? 150.283 114.993 157.966 1.00 78.84  ? 549 PHE A CD1 1 
ATOM   3733  C CD2 . PHE A 1 549 ? 152.126 115.365 156.426 1.00 69.40  ? 549 PHE A CD2 1 
ATOM   3734  C CE1 . PHE A 1 549 ? 151.101 114.153 158.741 1.00 71.76  ? 549 PHE A CE1 1 
ATOM   3735  C CE2 . PHE A 1 549 ? 152.940 114.527 157.204 1.00 70.30  ? 549 PHE A CE2 1 
ATOM   3736  C CZ  . PHE A 1 549 ? 152.431 113.921 158.360 1.00 70.00  ? 549 PHE A CZ  1 
ATOM   3737  N N   . GLY A 1 550 ? 151.685 119.191 155.759 1.00 72.70  ? 550 GLY A N   1 
ATOM   3738  C CA  . GLY A 1 550 ? 152.981 119.861 155.856 1.00 69.55  ? 550 GLY A CA  1 
ATOM   3739  C C   . GLY A 1 550 ? 152.997 121.005 156.868 1.00 74.92  ? 550 GLY A C   1 
ATOM   3740  O O   . GLY A 1 550 ? 153.946 121.124 157.641 1.00 74.15  ? 550 GLY A O   1 
ATOM   3741  N N   . PHE A 1 551 ? 151.934 121.813 156.911 1.00 63.50  ? 551 PHE A N   1 
ATOM   3742  C CA  . PHE A 1 551 ? 151.754 122.862 157.912 1.00 55.31  ? 551 PHE A CA  1 
ATOM   3743  C C   . PHE A 1 551 ? 151.282 122.322 159.273 1.00 68.14  ? 551 PHE A C   1 
ATOM   3744  O O   . PHE A 1 551 ? 151.686 122.868 160.296 1.00 72.43  ? 551 PHE A O   1 
ATOM   3745  C CB  . PHE A 1 551 ? 150.810 123.932 157.364 1.00 57.80  ? 551 PHE A CB  1 
ATOM   3746  C CG  . PHE A 1 551 ? 151.475 124.935 156.439 1.00 58.10  ? 551 PHE A CG  1 
ATOM   3747  C CD1 . PHE A 1 551 ? 152.134 126.043 156.994 1.00 65.17  ? 551 PHE A CD1 1 
ATOM   3748  C CD2 . PHE A 1 551 ? 151.408 124.806 155.040 1.00 58.78  ? 551 PHE A CD2 1 
ATOM   3749  C CE1 . PHE A 1 551 ? 152.734 127.000 156.164 1.00 66.71  ? 551 PHE A CE1 1 
ATOM   3750  C CE2 . PHE A 1 551 ? 151.995 125.772 154.209 1.00 59.33  ? 551 PHE A CE2 1 
ATOM   3751  C CZ  . PHE A 1 551 ? 152.667 126.864 154.770 1.00 62.94  ? 551 PHE A CZ  1 
ATOM   3752  N N   . ALA A 1 552 ? 150.495 121.243 159.350 1.00 65.89  ? 552 ALA A N   1 
ATOM   3753  C CA  . ALA A 1 552 ? 150.056 120.666 160.620 1.00 58.06  ? 552 ALA A CA  1 
ATOM   3754  C C   . ALA A 1 552 ? 151.213 120.099 161.451 1.00 63.76  ? 552 ALA A C   1 
ATOM   3755  O O   . ALA A 1 552 ? 151.337 120.436 162.626 1.00 67.33  ? 552 ALA A O   1 
ATOM   3756  C CB  . ALA A 1 552 ? 148.999 119.592 160.367 1.00 64.12  ? 552 ALA A CB  1 
ATOM   3757  N N   . VAL A 1 553 ? 152.110 119.294 160.872 1.00 73.55  ? 553 VAL A N   1 
ATOM   3758  C CA  . VAL A 1 553 ? 153.286 118.785 161.606 1.00 67.76  ? 553 VAL A CA  1 
ATOM   3759  C C   . VAL A 1 553 ? 154.204 119.918 162.075 1.00 70.82  ? 553 VAL A C   1 
ATOM   3760  O O   . VAL A 1 553 ? 154.907 119.783 163.072 1.00 72.52  ? 553 VAL A O   1 
ATOM   3761  C CB  . VAL A 1 553 ? 154.101 117.760 160.793 1.00 65.11  ? 553 VAL A CB  1 
ATOM   3762  C CG1 . VAL A 1 553 ? 153.295 116.494 160.528 1.00 66.18  ? 553 VAL A CG1 1 
ATOM   3763  C CG2 . VAL A 1 553 ? 154.631 118.270 159.452 1.00 67.05  ? 553 VAL A CG2 1 
ATOM   3764  N N   . ALA A 1 554 ? 154.188 121.056 161.390 1.00 69.96  ? 554 ALA A N   1 
ATOM   3765  C CA  . ALA A 1 554 ? 155.005 122.217 161.685 1.00 64.91  ? 554 ALA A CA  1 
ATOM   3766  C C   . ALA A 1 554 ? 154.446 123.061 162.827 1.00 72.00  ? 554 ALA A C   1 
ATOM   3767  O O   . ALA A 1 554 ? 155.159 123.349 163.782 1.00 76.31  ? 554 ALA A O   1 
ATOM   3768  C CB  . ALA A 1 554 ? 155.112 123.007 160.393 1.00 63.47  ? 554 ALA A CB  1 
ATOM   3769  N N   . LEU A 1 555 ? 153.162 123.413 162.779 1.00 80.52  ? 555 LEU A N   1 
ATOM   3770  C CA  . LEU A 1 555 ? 152.505 124.150 163.859 1.00 75.29  ? 555 LEU A CA  1 
ATOM   3771  C C   . LEU A 1 555 ? 152.488 123.348 165.157 1.00 74.63  ? 555 LEU A C   1 
ATOM   3772  O O   . LEU A 1 555 ? 152.711 123.935 166.210 1.00 77.83  ? 555 LEU A O   1 
ATOM   3773  C CB  . LEU A 1 555 ? 151.087 124.536 163.430 1.00 73.49  ? 555 LEU A CB  1 
ATOM   3774  C CG  . LEU A 1 555 ? 151.093 125.687 162.417 1.00 77.37  ? 555 LEU A CG  1 
ATOM   3775  C CD1 . LEU A 1 555 ? 149.782 125.711 161.666 1.00 80.50  ? 555 LEU A CD1 1 
ATOM   3776  C CD2 . LEU A 1 555 ? 151.249 127.038 163.103 1.00 76.97  ? 555 LEU A CD2 1 
ATOM   3777  N N   . VAL A 1 556 ? 152.312 122.027 165.103 1.00 73.70  ? 556 VAL A N   1 
ATOM   3778  C CA  . VAL A 1 556 ? 152.431 121.148 166.279 1.00 69.11  ? 556 VAL A CA  1 
ATOM   3779  C C   . VAL A 1 556 ? 153.840 121.156 166.867 1.00 78.11  ? 556 VAL A C   1 
ATOM   3780  O O   . VAL A 1 556 ? 154.003 121.267 168.074 1.00 83.15  ? 556 VAL A O   1 
ATOM   3781  C CB  . VAL A 1 556 ? 152.018 119.714 165.917 1.00 75.27  ? 556 VAL A CB  1 
ATOM   3782  C CG1 . VAL A 1 556 ? 152.290 118.695 167.017 1.00 75.39  ? 556 VAL A CG1 1 
ATOM   3783  C CG2 . VAL A 1 556 ? 150.524 119.680 165.642 1.00 82.31  ? 556 VAL A CG2 1 
ATOM   3784  N N   . SER A 1 557 ? 154.874 121.080 166.028 1.00 85.43  ? 557 SER A N   1 
ATOM   3785  C CA  . SER A 1 557 ? 156.272 121.086 166.470 1.00 80.67  ? 557 SER A CA  1 
ATOM   3786  C C   . SER A 1 557 ? 156.677 122.406 167.121 1.00 79.59  ? 557 SER A C   1 
ATOM   3787  O O   . SER A 1 557 ? 157.427 122.405 168.089 1.00 78.40  ? 557 SER A O   1 
ATOM   3788  C CB  . SER A 1 557 ? 157.192 120.805 165.285 1.00 78.82  ? 557 SER A CB  1 
ATOM   3789  O OG  . SER A 1 557 ? 156.907 119.536 164.740 1.00 78.06  ? 557 SER A OG  1 
ATOM   3790  N N   . LEU A 1 558 ? 156.173 123.534 166.619 1.00 80.65  ? 558 LEU A N   1 
ATOM   3791  C CA  . LEU A 1 558 ? 156.541 124.866 167.089 1.00 77.52  ? 558 LEU A CA  1 
ATOM   3792  C C   . LEU A 1 558 ? 155.687 125.376 168.262 1.00 84.88  ? 558 LEU A C   1 
ATOM   3793  O O   . LEU A 1 558 ? 156.180 126.094 169.126 1.00 86.63  ? 558 LEU A O   1 
ATOM   3794  C CB  . LEU A 1 558 ? 156.459 125.801 165.879 1.00 71.01  ? 558 LEU A CB  1 
ATOM   3795  C CG  . LEU A 1 558 ? 157.250 127.098 166.017 1.00 81.43  ? 558 LEU A CG  1 
ATOM   3796  C CD1 . LEU A 1 558 ? 158.748 126.871 166.201 1.00 78.60  ? 558 LEU A CD1 1 
ATOM   3797  C CD2 . LEU A 1 558 ? 157.078 127.896 164.740 1.00 80.41  ? 558 LEU A CD2 1 
ATOM   3798  N N   . SER A 1 559 ? 154.416 124.971 168.338 1.00 88.53  ? 559 SER A N   1 
ATOM   3799  C CA  . SER A 1 559 ? 153.513 125.320 169.448 1.00 86.88  ? 559 SER A CA  1 
ATOM   3800  C C   . SER A 1 559 ? 153.768 124.518 170.731 1.00 93.63  ? 559 SER A C   1 
ATOM   3801  O O   . SER A 1 559 ? 153.050 124.677 171.718 1.00 95.76  ? 559 SER A O   1 
ATOM   3802  C CB  . SER A 1 559 ? 152.049 125.153 169.045 1.00 90.61  ? 559 SER A CB  1 
ATOM   3803  O OG  . SER A 1 559 ? 151.792 125.846 167.845 1.00 94.97  ? 559 SER A OG  1 
ATOM   3804  N N   . ARG A 1 560 ? 154.773 123.638 170.739 1.00 99.54  ? 560 ARG A N   1 
ATOM   3805  C CA  . ARG A 1 560 ? 155.155 122.809 171.888 1.00 99.51  ? 560 ARG A CA  1 
ATOM   3806  C C   . ARG A 1 560 ? 155.846 123.595 173.012 1.00 99.95  ? 560 ARG A C   1 
ATOM   3807  O O   . ARG A 1 560 ? 155.794 123.175 174.165 1.00 97.44  ? 560 ARG A O   1 
ATOM   3808  C CB  . ARG A 1 560 ? 156.032 121.672 171.345 1.00 101.03 ? 560 ARG A CB  1 
ATOM   3809  C CG  . ARG A 1 560 ? 156.122 120.474 172.296 1.00 100.93 ? 560 ARG A CG  1 
ATOM   3810  C CD  . ARG A 1 560 ? 157.018 119.366 171.726 1.00 101.54 ? 560 ARG A CD  1 
ATOM   3811  N NE  . ARG A 1 560 ? 156.498 118.799 170.467 1.00 101.57 ? 560 ARG A NE  1 
ATOM   3812  C CZ  . ARG A 1 560 ? 155.591 117.852 170.343 1.00 99.82  ? 560 ARG A CZ  1 
ATOM   3813  N NH1 . ARG A 1 560 ? 155.247 117.410 169.171 1.00 96.21  ? 560 ARG A NH1 1 
ATOM   3814  N NH2 . ARG A 1 560 ? 155.016 117.310 171.369 1.00 100.21 ? 560 ARG A NH2 1 
ATOM   3815  N N   . GLU A 1 561 ? 156.455 124.745 172.715 1.00 112.16 ? 561 GLU A N   1 
ATOM   3816  C CA  . GLU A 1 561 ? 157.238 125.532 173.681 1.00 115.04 ? 561 GLU A CA  1 
ATOM   3817  C C   . GLU A 1 561 ? 156.460 126.752 174.215 1.00 112.99 ? 561 GLU A C   1 
ATOM   3818  O O   . GLU A 1 561 ? 156.022 127.614 173.453 1.00 109.01 ? 561 GLU A O   1 
ATOM   3819  C CB  . GLU A 1 561 ? 158.569 125.988 173.046 1.00 114.67 ? 561 GLU A CB  1 
ATOM   3820  C CG  . GLU A 1 561 ? 159.454 124.854 172.507 1.00 111.78 ? 561 GLU A CG  1 
ATOM   3821  C CD  . GLU A 1 561 ? 159.657 123.702 173.506 1.00 115.59 ? 561 GLU A CD  1 
ATOM   3822  O OE1 . GLU A 1 561 ? 160.099 123.959 174.650 1.00 112.12 ? 561 GLU A OE1 1 
ATOM   3823  O OE2 . GLU A 1 561 ? 159.370 122.542 173.139 1.00 116.81 ? 561 GLU A OE2 1 
ATOM   3824  N N   . ALA A 1 562 ? 156.331 126.857 175.540 1.00 114.38 ? 562 ALA A N   1 
ATOM   3825  C CA  . ALA A 1 562 ? 155.746 128.006 176.238 1.00 115.32 ? 562 ALA A CA  1 
ATOM   3826  C C   . ALA A 1 562 ? 156.779 129.117 176.519 1.00 117.00 ? 562 ALA A C   1 
ATOM   3827  O O   . ALA A 1 562 ? 157.982 128.859 176.627 1.00 117.39 ? 562 ALA A O   1 
ATOM   3828  C CB  . ALA A 1 562 ? 155.083 127.505 177.520 1.00 110.72 ? 562 ALA A CB  1 
ATOM   3829  N N   . ARG A 1 563 ? 156.326 130.367 176.630 1.00 111.73 ? 563 ARG A N   1 
ATOM   3830  C CA  . ARG A 1 563 ? 157.181 131.549 176.763 1.00 111.25 ? 563 ARG A CA  1 
ATOM   3831  C C   . ARG A 1 563 ? 157.906 131.625 178.112 1.00 109.78 ? 563 ARG A C   1 
ATOM   3832  O O   . ARG A 1 563 ? 157.365 132.089 179.117 1.00 111.67 ? 563 ARG A O   1 
ATOM   3833  C CB  . ARG A 1 563 ? 156.344 132.800 176.504 1.00 107.83 ? 563 ARG A CB  1 
ATOM   3834  N N   . PRO A 1 589 ? 144.778 125.219 170.933 1.00 113.02 ? 589 PRO A N   1 
ATOM   3835  C CA  . PRO A 1 589 ? 145.112 124.791 169.584 1.00 112.47 ? 589 PRO A CA  1 
ATOM   3836  C C   . PRO A 1 589 ? 146.457 124.060 169.454 1.00 110.98 ? 589 PRO A C   1 
ATOM   3837  O O   . PRO A 1 589 ? 147.329 124.146 170.321 1.00 105.95 ? 589 PRO A O   1 
ATOM   3838  C CB  . PRO A 1 589 ? 145.075 126.075 168.752 1.00 112.55 ? 589 PRO A CB  1 
ATOM   3839  C CG  . PRO A 1 589 ? 143.989 126.888 169.440 1.00 108.68 ? 589 PRO A CG  1 
ATOM   3840  C CD  . PRO A 1 589 ? 144.214 126.552 170.910 1.00 111.28 ? 589 PRO A CD  1 
ATOM   3841  N N   . TYR A 1 590 ? 146.633 123.364 168.326 1.00 105.98 ? 590 TYR A N   1 
ATOM   3842  C CA  . TYR A 1 590 ? 147.900 122.767 167.867 1.00 103.67 ? 590 TYR A CA  1 
ATOM   3843  C C   . TYR A 1 590 ? 148.535 121.737 168.822 1.00 99.99  ? 590 TYR A C   1 
ATOM   3844  O O   . TYR A 1 590 ? 149.749 121.564 168.838 1.00 97.79  ? 590 TYR A O   1 
ATOM   3845  C CB  . TYR A 1 590 ? 148.921 123.874 167.585 1.00 100.81 ? 590 TYR A CB  1 
ATOM   3846  C CG  . TYR A 1 590 ? 148.361 125.057 166.839 1.00 101.34 ? 590 TYR A CG  1 
ATOM   3847  C CD1 . TYR A 1 590 ? 147.958 124.943 165.519 1.00 101.38 ? 590 TYR A CD1 1 
ATOM   3848  C CD2 . TYR A 1 590 ? 148.226 126.291 167.453 1.00 99.35  ? 590 TYR A CD2 1 
ATOM   3849  C CE1 . TYR A 1 590 ? 147.436 126.023 164.827 1.00 102.83 ? 590 TYR A CE1 1 
ATOM   3850  C CE2 . TYR A 1 590 ? 147.707 127.381 166.777 1.00 100.41 ? 590 TYR A CE2 1 
ATOM   3851  C CZ  . TYR A 1 590 ? 147.311 127.247 165.459 1.00 103.77 ? 590 TYR A CZ  1 
ATOM   3852  O OH  . TYR A 1 590 ? 146.797 128.317 164.787 1.00 102.97 ? 590 TYR A OH  1 
ATOM   3853  N N   . ARG A 1 591 ? 147.725 121.030 169.614 1.00 103.48 ? 591 ARG A N   1 
ATOM   3854  C CA  . ARG A 1 591 ? 148.192 120.024 170.571 1.00 104.14 ? 591 ARG A CA  1 
ATOM   3855  C C   . ARG A 1 591 ? 148.614 118.690 169.937 1.00 103.67 ? 591 ARG A C   1 
ATOM   3856  O O   . ARG A 1 591 ? 149.430 117.963 170.503 1.00 103.73 ? 591 ARG A O   1 
ATOM   3857  C CB  . ARG A 1 591 ? 147.073 119.771 171.573 1.00 98.86  ? 591 ARG A CB  1 
ATOM   3858  N N   . SER A 1 592 ? 148.067 118.346 168.769 1.00 91.79  ? 592 SER A N   1 
ATOM   3859  C CA  . SER A 1 592 ? 148.293 117.069 168.079 1.00 92.93  ? 592 SER A CA  1 
ATOM   3860  C C   . SER A 1 592 ? 148.136 117.224 166.568 1.00 91.19  ? 592 SER A C   1 
ATOM   3861  O O   . SER A 1 592 ? 147.594 118.224 166.102 1.00 91.10  ? 592 SER A O   1 
ATOM   3862  C CB  . SER A 1 592 ? 147.341 115.984 168.606 1.00 94.20  ? 592 SER A CB  1 
ATOM   3863  O OG  . SER A 1 592 ? 146.037 116.108 168.070 1.00 98.00  ? 592 SER A OG  1 
ATOM   3864  N N   . ILE A 1 593 ? 148.585 116.245 165.777 1.00 90.67  ? 593 ILE A N   1 
ATOM   3865  C CA  . ILE A 1 593 ? 148.455 116.288 164.311 1.00 90.67  ? 593 ILE A CA  1 
ATOM   3866  C C   . ILE A 1 593 ? 146.984 116.378 163.889 1.00 89.85  ? 593 ILE A C   1 
ATOM   3867  O O   . ILE A 1 593 ? 146.662 117.121 162.964 1.00 92.66  ? 593 ILE A O   1 
ATOM   3868  C CB  . ILE A 1 593 ? 149.130 115.069 163.637 1.00 92.36  ? 593 ILE A CB  1 
ATOM   3869  C CG1 . ILE A 1 593 ? 150.583 114.808 164.085 1.00 91.13  ? 593 ILE A CG1 1 
ATOM   3870  C CG2 . ILE A 1 593 ? 149.078 115.209 162.108 1.00 87.30  ? 593 ILE A CG2 1 
ATOM   3871  C CD1 . ILE A 1 593 ? 151.526 115.999 163.935 1.00 91.58  ? 593 ILE A CD1 1 
ATOM   3872  N N   . LEU A 1 594 ? 146.083 115.670 164.578 1.00 87.34  ? 594 LEU A N   1 
ATOM   3873  C CA  . LEU A 1 594 ? 144.642 115.726 164.334 1.00 90.86  ? 594 LEU A CA  1 
ATOM   3874  C C   . LEU A 1 594 ? 144.083 117.117 164.646 1.00 92.67  ? 594 LEU A C   1 
ATOM   3875  O O   . LEU A 1 594 ? 143.428 117.711 163.798 1.00 96.34  ? 594 LEU A O   1 
ATOM   3876  C CB  . LEU A 1 594 ? 143.950 114.625 165.159 1.00 95.30  ? 594 LEU A CB  1 
ATOM   3877  C CG  . LEU A 1 594 ? 142.410 114.661 165.126 1.00 96.66  ? 594 LEU A CG  1 
ATOM   3878  C CD1 . LEU A 1 594 ? 141.846 114.499 163.719 1.00 91.56  ? 594 LEU A CD1 1 
ATOM   3879  C CD2 . LEU A 1 594 ? 141.858 113.542 166.003 1.00 91.87  ? 594 LEU A CD2 1 
ATOM   3880  N N   . ASP A 1 595 ? 144.374 117.661 165.827 1.00 87.55  ? 595 ASP A N   1 
ATOM   3881  C CA  . ASP A 1 595 ? 143.877 118.978 166.228 1.00 85.20  ? 595 ASP A CA  1 
ATOM   3882  C C   . ASP A 1 595 ? 144.400 120.099 165.328 1.00 89.27  ? 595 ASP A C   1 
ATOM   3883  O O   . ASP A 1 595 ? 143.626 120.951 164.914 1.00 92.26  ? 595 ASP A O   1 
ATOM   3884  C CB  . ASP A 1 595 ? 144.243 119.263 167.688 1.00 94.94  ? 595 ASP A CB  1 
ATOM   3885  C CG  . ASP A 1 595 ? 143.664 118.229 168.651 1.00 101.45 ? 595 ASP A CG  1 
ATOM   3886  O OD1 . ASP A 1 595 ? 142.438 117.992 168.620 1.00 96.51  ? 595 ASP A OD1 1 
ATOM   3887  O OD2 . ASP A 1 595 ? 144.454 117.641 169.426 1.00 102.93 ? 595 ASP A OD2 1 
ATOM   3888  N N   . ALA A 1 596 ? 145.683 120.094 164.962 1.00 87.25  ? 596 ALA A N   1 
ATOM   3889  C CA  . ALA A 1 596 ? 146.238 121.060 164.020 1.00 80.05  ? 596 ALA A CA  1 
ATOM   3890  C C   . ALA A 1 596 ? 145.679 120.886 162.604 1.00 79.86  ? 596 ALA A C   1 
ATOM   3891  O O   . ALA A 1 596 ? 145.352 121.875 161.968 1.00 85.49  ? 596 ALA A O   1 
ATOM   3892  C CB  . ALA A 1 596 ? 147.755 120.950 164.035 1.00 78.13  ? 596 ALA A CB  1 
ATOM   3893  N N   . SER A 1 597 ? 145.482 119.658 162.121 1.00 80.04  ? 597 SER A N   1 
ATOM   3894  C CA  . SER A 1 597 ? 144.799 119.421 160.844 1.00 72.13  ? 597 SER A CA  1 
ATOM   3895  C C   . SER A 1 597 ? 143.371 119.947 160.868 1.00 73.22  ? 597 SER A C   1 
ATOM   3896  O O   . SER A 1 597 ? 142.909 120.486 159.874 1.00 81.98  ? 597 SER A O   1 
ATOM   3897  C CB  . SER A 1 597 ? 144.754 117.932 160.490 1.00 78.38  ? 597 SER A CB  1 
ATOM   3898  O OG  . SER A 1 597 ? 146.053 117.392 160.375 1.00 86.22  ? 597 SER A OG  1 
ATOM   3899  N N   . LEU A 1 598 ? 142.663 119.839 161.994 1.00 77.79  ? 598 LEU A N   1 
ATOM   3900  C CA  . LEU A 1 598 ? 141.300 120.332 162.127 1.00 80.55  ? 598 LEU A CA  1 
ATOM   3901  C C   . LEU A 1 598 ? 141.231 121.860 162.254 1.00 81.77  ? 598 LEU A C   1 
ATOM   3902  O O   . LEU A 1 598 ? 140.411 122.485 161.595 1.00 90.73  ? 598 LEU A O   1 
ATOM   3903  C CB  . LEU A 1 598 ? 140.637 119.597 163.299 1.00 76.49  ? 598 LEU A CB  1 
ATOM   3904  C CG  . LEU A 1 598 ? 139.115 119.755 163.331 1.00 83.69  ? 598 LEU A CG  1 
ATOM   3905  C CD1 . LEU A 1 598 ? 138.452 119.089 162.127 1.00 82.50  ? 598 LEU A CD1 1 
ATOM   3906  C CD2 . LEU A 1 598 ? 138.567 119.117 164.599 1.00 80.72  ? 598 LEU A CD2 1 
ATOM   3907  N N   . GLU A 1 599 ? 142.109 122.494 163.025 1.00 74.09  ? 599 GLU A N   1 
ATOM   3908  C CA  . GLU A 1 599 ? 142.215 123.956 163.105 1.00 68.33  ? 599 GLU A CA  1 
ATOM   3909  C C   . GLU A 1 599 ? 142.619 124.582 161.769 1.00 71.42  ? 599 GLU A C   1 
ATOM   3910  O O   . GLU A 1 599 ? 142.029 125.572 161.346 1.00 75.44  ? 599 GLU A O   1 
ATOM   3911  C CB  . GLU A 1 599 ? 143.230 124.353 164.188 1.00 78.34  ? 599 GLU A CB  1 
ATOM   3912  C CG  . GLU A 1 599 ? 142.764 124.097 165.630 1.00 82.84  ? 599 GLU A CG  1 
ATOM   3913  C CD  . GLU A 1 599 ? 141.424 124.762 165.979 1.00 84.59  ? 599 GLU A CD  1 
ATOM   3914  O OE1 . GLU A 1 599 ? 141.173 125.890 165.523 1.00 82.39  ? 599 GLU A OE1 1 
ATOM   3915  O OE2 . GLU A 1 599 ? 140.596 124.137 166.681 1.00 82.64  ? 599 GLU A OE2 1 
ATOM   3916  N N   . LEU A 1 600 ? 143.579 123.988 161.057 1.00 63.30  ? 600 LEU A N   1 
ATOM   3917  C CA  . LEU A 1 600 ? 143.929 124.386 159.698 1.00 51.34  ? 600 LEU A CA  1 
ATOM   3918  C C   . LEU A 1 600 ? 142.826 124.069 158.693 1.00 42.46  ? 600 LEU A C   1 
ATOM   3919  O O   . LEU A 1 600 ? 142.669 124.802 157.722 1.00 51.92  ? 600 LEU A O   1 
ATOM   3920  C CB  . LEU A 1 600 ? 145.210 123.679 159.259 1.00 64.09  ? 600 LEU A CB  1 
ATOM   3921  C CG  . LEU A 1 600 ? 146.515 124.130 159.917 1.00 53.68  ? 600 LEU A CG  1 
ATOM   3922  C CD1 . LEU A 1 600 ? 147.637 123.343 159.254 1.00 58.16  ? 600 LEU A CD1 1 
ATOM   3923  C CD2 . LEU A 1 600 ? 146.767 125.612 159.702 1.00 57.26  ? 600 LEU A CD2 1 
ATOM   3924  N N   . PHE A 1 601 ? 142.040 123.008 158.876 1.00 57.21  ? 601 PHE A N   1 
ATOM   3925  C CA  . PHE A 1 601 ? 140.916 122.761 157.979 1.00 62.58  ? 601 PHE A CA  1 
ATOM   3926  C C   . PHE A 1 601 ? 139.801 123.788 158.197 1.00 71.73  ? 601 PHE A C   1 
ATOM   3927  O O   . PHE A 1 601 ? 139.232 124.285 157.228 1.00 67.31  ? 601 PHE A O   1 
ATOM   3928  C CB  . PHE A 1 601 ? 140.385 121.335 158.132 1.00 60.29  ? 601 PHE A CB  1 
ATOM   3929  C CG  . PHE A 1 601 ? 139.187 121.078 157.246 1.00 67.25  ? 601 PHE A CG  1 
ATOM   3930  C CD1 . PHE A 1 601 ? 139.363 120.892 155.864 1.00 67.56  ? 601 PHE A CD1 1 
ATOM   3931  C CD2 . PHE A 1 601 ? 137.884 121.118 157.779 1.00 73.35  ? 601 PHE A CD2 1 
ATOM   3932  C CE1 . PHE A 1 601 ? 138.247 120.755 155.023 1.00 68.06  ? 601 PHE A CE1 1 
ATOM   3933  C CE2 . PHE A 1 601 ? 136.771 120.982 156.939 1.00 66.49  ? 601 PHE A CE2 1 
ATOM   3934  C CZ  . PHE A 1 601 ? 136.951 120.808 155.557 1.00 67.07  ? 601 PHE A CZ  1 
ATOM   3935  N N   . LYS A 1 602 ? 139.548 124.219 159.435 1.00 78.66  ? 602 LYS A N   1 
ATOM   3936  C CA  . LYS A 1 602 ? 138.530 125.223 159.725 1.00 54.48  ? 602 LYS A CA  1 
ATOM   3937  C C   . LYS A 1 602 ? 138.697 126.528 158.953 1.00 51.26  ? 602 LYS A C   1 
ATOM   3938  O O   . LYS A 1 602 ? 137.696 127.161 158.645 1.00 70.64  ? 602 LYS A O   1 
ATOM   3939  C CB  . LYS A 1 602 ? 138.436 125.477 161.227 1.00 61.47  ? 602 LYS A CB  1 
ATOM   3940  C CG  . LYS A 1 602 ? 137.509 124.466 161.900 1.00 62.44  ? 602 LYS A CG  1 
ATOM   3941  C CD  . LYS A 1 602 ? 137.199 124.859 163.347 1.00 62.42  ? 602 LYS A CD  1 
ATOM   3942  C CE  . LYS A 1 602 ? 138.377 124.526 164.256 1.00 70.18  ? 602 LYS A CE  1 
ATOM   3943  N NZ  . LYS A 1 602 ? 138.126 124.907 165.662 1.00 75.82  ? 602 LYS A NZ  1 
ATOM   3944  N N   . PHE A 1 603 ? 139.895 126.912 158.515 1.00 66.12  ? 603 PHE A N   1 
ATOM   3945  C CA  . PHE A 1 603 ? 140.104 128.077 157.636 1.00 71.80  ? 603 PHE A CA  1 
ATOM   3946  C C   . PHE A 1 603 ? 139.390 127.999 156.281 1.00 71.13  ? 603 PHE A C   1 
ATOM   3947  O O   . PHE A 1 603 ? 139.122 129.036 155.683 1.00 73.97  ? 603 PHE A O   1 
ATOM   3948  C CB  . PHE A 1 603 ? 141.592 128.258 157.349 1.00 65.53  ? 603 PHE A CB  1 
ATOM   3949  C CG  . PHE A 1 603 ? 142.355 128.964 158.439 1.00 67.28  ? 603 PHE A CG  1 
ATOM   3950  C CD1 . PHE A 1 603 ? 142.414 130.363 158.443 1.00 65.03  ? 603 PHE A CD1 1 
ATOM   3951  C CD2 . PHE A 1 603 ? 143.004 128.231 159.440 1.00 67.75  ? 603 PHE A CD2 1 
ATOM   3952  C CE1 . PHE A 1 603 ? 143.157 131.029 159.427 1.00 63.33  ? 603 PHE A CE1 1 
ATOM   3953  C CE2 . PHE A 1 603 ? 143.746 128.899 160.429 1.00 66.60  ? 603 PHE A CE2 1 
ATOM   3954  C CZ  . PHE A 1 603 ? 143.826 130.293 160.419 1.00 66.74  ? 603 PHE A CZ  1 
ATOM   3955  N N   . THR A 1 604 ? 139.096 126.805 155.774 1.00 70.57  ? 604 THR A N   1 
ATOM   3956  C CA  . THR A 1 604 ? 138.392 126.641 154.494 1.00 63.22  ? 604 THR A CA  1 
ATOM   3957  C C   . THR A 1 604 ? 136.875 126.721 154.645 1.00 75.92  ? 604 THR A C   1 
ATOM   3958  O O   . THR A 1 604 ? 136.202 127.110 153.695 1.00 78.60  ? 604 THR A O   1 
ATOM   3959  C CB  . THR A 1 604 ? 138.770 125.340 153.793 1.00 63.29  ? 604 THR A CB  1 
ATOM   3960  O OG1 . THR A 1 604 ? 138.364 124.222 154.538 1.00 67.46  ? 604 THR A OG1 1 
ATOM   3961  C CG2 . THR A 1 604 ? 140.265 125.242 153.546 1.00 75.10  ? 604 THR A CG2 1 
ATOM   3962  N N   . ILE A 1 605 ? 136.324 126.433 155.836 1.00 74.54  ? 605 ILE A N   1 
ATOM   3963  C CA  . ILE A 1 605 ? 134.896 126.653 156.133 1.00 64.19  ? 605 ILE A CA  1 
ATOM   3964  C C   . ILE A 1 605 ? 134.590 128.068 156.673 1.00 63.45  ? 605 ILE A C   1 
ATOM   3965  O O   . ILE A 1 605 ? 133.458 128.345 157.049 1.00 66.40  ? 605 ILE A O   1 
ATOM   3966  C CB  . ILE A 1 605 ? 134.335 125.544 157.042 1.00 58.94  ? 605 ILE A CB  1 
ATOM   3967  C CG1 . ILE A 1 605 ? 134.858 125.615 158.484 1.00 61.60  ? 605 ILE A CG1 1 
ATOM   3968  C CG2 . ILE A 1 605 ? 134.602 124.167 156.428 1.00 59.44  ? 605 ILE A CG2 1 
ATOM   3969  C CD1 . ILE A 1 605 ? 134.050 124.799 159.485 1.00 56.83  ? 605 ILE A CD1 1 
ATOM   3970  N N   . GLY A 1 606 ? 135.587 128.955 156.729 1.00 59.82  ? 606 GLY A N   1 
ATOM   3971  C CA  . GLY A 1 606 ? 135.464 130.324 157.225 1.00 56.98  ? 606 GLY A CA  1 
ATOM   3972  C C   . GLY A 1 606 ? 135.555 130.499 158.745 1.00 69.22  ? 606 GLY A C   1 
ATOM   3973  O O   . GLY A 1 606 ? 135.220 131.575 159.227 1.00 75.55  ? 606 GLY A O   1 
ATOM   3974  N N   . MET A 1 607 ? 136.006 129.488 159.506 1.00 67.07  ? 607 MET A N   1 
ATOM   3975  C CA  . MET A 1 607 ? 136.069 129.487 160.982 1.00 64.06  ? 607 MET A CA  1 
ATOM   3976  C C   . MET A 1 607 ? 137.507 129.519 161.520 1.00 62.34  ? 607 MET A C   1 
ATOM   3977  O O   . MET A 1 607 ? 137.854 128.794 162.442 1.00 67.09  ? 607 MET A O   1 
ATOM   3978  C CB  . MET A 1 607 ? 135.242 128.322 161.555 1.00 64.06  ? 607 MET A CB  1 
ATOM   3979  C CG  . MET A 1 607 ? 133.734 128.519 161.377 1.00 61.75  ? 607 MET A CG  1 
ATOM   3980  S SD  . MET A 1 607 ? 132.959 129.716 162.495 1.00 63.01  ? 607 MET A SD  1 
ATOM   3981  C CE  . MET A 1 607 ? 132.866 128.793 164.042 1.00 60.99  ? 607 MET A CE  1 
ATOM   3982  N N   . GLY A 1 608 ? 138.388 130.304 160.897 1.00 67.37  ? 608 GLY A N   1 
ATOM   3983  C CA  . GLY A 1 608 ? 139.844 130.191 161.027 1.00 67.92  ? 608 GLY A CA  1 
ATOM   3984  C C   . GLY A 1 608 ? 140.478 130.334 162.421 1.00 74.14  ? 608 GLY A C   1 
ATOM   3985  O O   . GLY A 1 608 ? 141.465 129.667 162.693 1.00 85.52  ? 608 GLY A O   1 
ATOM   3986  N N   . GLU A 1 609 ? 139.962 131.182 163.313 1.00 87.10  ? 609 GLU A N   1 
ATOM   3987  C CA  . GLU A 1 609 ? 140.563 131.418 164.649 1.00 91.22  ? 609 GLU A CA  1 
ATOM   3988  C C   . GLU A 1 609 ? 142.042 131.883 164.583 1.00 89.62  ? 609 GLU A C   1 
ATOM   3989  O O   . GLU A 1 609 ? 142.901 131.459 165.354 1.00 88.49  ? 609 GLU A O   1 
ATOM   3990  C CB  . GLU A 1 609 ? 140.322 130.232 165.619 1.00 91.12  ? 609 GLU A CB  1 
ATOM   3991  C CG  . GLU A 1 609 ? 138.832 129.903 165.819 1.00 95.08  ? 609 GLU A CG  1 
ATOM   3992  C CD  . GLU A 1 609 ? 138.611 128.685 166.732 1.00 97.36  ? 609 GLU A CD  1 
ATOM   3993  O OE1 . GLU A 1 609 ? 138.965 128.766 167.930 1.00 93.83  ? 609 GLU A OE1 1 
ATOM   3994  O OE2 . GLU A 1 609 ? 138.022 127.672 166.280 1.00 98.11  ? 609 GLU A OE2 1 
ATOM   3995  N N   . LEU A 1 610 ? 142.343 132.778 163.638 1.00 81.33  ? 610 LEU A N   1 
ATOM   3996  C CA  . LEU A 1 610 ? 143.657 133.381 163.389 1.00 77.94  ? 610 LEU A CA  1 
ATOM   3997  C C   . LEU A 1 610 ? 144.041 134.419 164.463 1.00 80.86  ? 610 LEU A C   1 
ATOM   3998  O O   . LEU A 1 610 ? 143.400 135.461 164.565 1.00 84.45  ? 610 LEU A O   1 
ATOM   3999  C CB  . LEU A 1 610 ? 143.562 134.015 161.990 1.00 80.88  ? 610 LEU A CB  1 
ATOM   4000  C CG  . LEU A 1 610 ? 144.808 134.727 161.468 1.00 81.44  ? 610 LEU A CG  1 
ATOM   4001  C CD1 . LEU A 1 610 ? 145.993 133.793 161.281 1.00 83.52  ? 610 LEU A CD1 1 
ATOM   4002  C CD2 . LEU A 1 610 ? 144.491 135.315 160.104 1.00 81.25  ? 610 LEU A CD2 1 
ATOM   4003  N N   . ALA A 1 611 ? 145.082 134.171 165.259 1.00 99.90  ? 611 ALA A N   1 
ATOM   4004  C CA  . ALA A 1 611 ? 145.431 135.015 166.407 1.00 99.36  ? 611 ALA A CA  1 
ATOM   4005  C C   . ALA A 1 611 ? 146.926 134.991 166.767 1.00 101.47 ? 611 ALA A C   1 
ATOM   4006  O O   . ALA A 1 611 ? 147.628 134.013 166.516 1.00 103.85 ? 611 ALA A O   1 
ATOM   4007  C CB  . ALA A 1 611 ? 144.595 134.564 167.611 1.00 96.19  ? 611 ALA A CB  1 
ATOM   4008  N N   . PHE A 1 612 ? 147.399 136.053 167.421 1.00 106.52 ? 612 PHE A N   1 
ATOM   4009  C CA  . PHE A 1 612 ? 148.733 136.147 168.016 1.00 105.40 ? 612 PHE A CA  1 
ATOM   4010  C C   . PHE A 1 612 ? 148.727 135.512 169.419 1.00 106.94 ? 612 PHE A C   1 
ATOM   4011  O O   . PHE A 1 612 ? 148.446 136.182 170.411 1.00 108.04 ? 612 PHE A O   1 
ATOM   4012  C CB  . PHE A 1 612 ? 149.134 137.631 168.017 1.00 105.42 ? 612 PHE A CB  1 
ATOM   4013  C CG  . PHE A 1 612 ? 150.552 137.937 168.446 1.00 108.01 ? 612 PHE A CG  1 
ATOM   4014  C CD1 . PHE A 1 612 ? 151.618 137.721 167.558 1.00 106.04 ? 612 PHE A CD1 1 
ATOM   4015  C CD2 . PHE A 1 612 ? 150.805 138.517 169.703 1.00 106.98 ? 612 PHE A CD2 1 
ATOM   4016  C CE1 . PHE A 1 612 ? 152.922 138.096 167.910 1.00 106.21 ? 612 PHE A CE1 1 
ATOM   4017  C CE2 . PHE A 1 612 ? 152.110 138.902 170.053 1.00 105.99 ? 612 PHE A CE2 1 
ATOM   4018  C CZ  . PHE A 1 612 ? 153.170 138.693 169.158 1.00 106.30 ? 612 PHE A CZ  1 
ATOM   4019  N N   . GLN A 1 613 ? 148.972 134.200 169.499 1.00 111.68 ? 613 GLN A N   1 
ATOM   4020  C CA  . GLN A 1 613 ? 148.836 133.400 170.726 1.00 113.07 ? 613 GLN A CA  1 
ATOM   4021  C C   . GLN A 1 613 ? 149.776 133.893 171.840 1.00 112.93 ? 613 GLN A C   1 
ATOM   4022  O O   . GLN A 1 613 ? 150.992 133.847 171.685 1.00 112.90 ? 613 GLN A O   1 
ATOM   4023  C CB  . GLN A 1 613 ? 149.154 131.925 170.408 1.00 109.90 ? 613 GLN A CB  1 
ATOM   4024  C CG  . GLN A 1 613 ? 148.250 131.253 169.361 1.00 111.97 ? 613 GLN A CG  1 
ATOM   4025  C CD  . GLN A 1 613 ? 146.815 131.008 169.819 1.00 115.79 ? 613 GLN A CD  1 
ATOM   4026  O OE1 . GLN A 1 613 ? 146.441 131.192 170.967 1.00 115.54 ? 613 GLN A OE1 1 
ATOM   4027  N NE2 . GLN A 1 613 ? 145.947 130.575 168.936 1.00 110.67 ? 613 GLN A NE2 1 
ATOM   4028  N N   . GLU A 1 614 ? 149.271 134.365 172.980 1.00 118.01 ? 614 GLU A N   1 
ATOM   4029  C CA  . GLU A 1 614 ? 150.120 135.061 173.960 1.00 118.38 ? 614 GLU A CA  1 
ATOM   4030  C C   . GLU A 1 614 ? 151.132 134.150 174.686 1.00 121.37 ? 614 GLU A C   1 
ATOM   4031  O O   . GLU A 1 614 ? 152.227 134.604 175.016 1.00 120.85 ? 614 GLU A O   1 
ATOM   4032  C CB  . GLU A 1 614 ? 149.262 135.793 175.004 1.00 117.04 ? 614 GLU A CB  1 
ATOM   4033  N N   . GLN A 1 615 ? 150.786 132.887 174.950 1.00 118.27 ? 615 GLN A N   1 
ATOM   4034  C CA  . GLN A 1 615 ? 151.555 131.984 175.814 1.00 115.14 ? 615 GLN A CA  1 
ATOM   4035  C C   . GLN A 1 615 ? 152.684 131.215 175.109 1.00 116.41 ? 615 GLN A C   1 
ATOM   4036  O O   . GLN A 1 615 ? 153.574 130.693 175.780 1.00 118.78 ? 615 GLN A O   1 
ATOM   4037  C CB  . GLN A 1 615 ? 150.596 131.029 176.556 1.00 112.47 ? 615 GLN A CB  1 
ATOM   4038  C CG  . GLN A 1 615 ? 150.162 129.735 175.837 1.00 113.92 ? 615 GLN A CG  1 
ATOM   4039  C CD  . GLN A 1 615 ? 149.181 129.910 174.679 1.00 117.31 ? 615 GLN A CD  1 
ATOM   4040  O OE1 . GLN A 1 615 ? 148.860 131.004 174.242 1.00 117.97 ? 615 GLN A OE1 1 
ATOM   4041  N NE2 . GLN A 1 615 ? 148.664 128.833 174.136 1.00 115.18 ? 615 GLN A NE2 1 
ATOM   4042  N N   . LEU A 1 616 ? 152.650 131.104 173.776 1.00 106.51 ? 616 LEU A N   1 
ATOM   4043  C CA  . LEU A 1 616 ? 153.648 130.363 172.997 1.00 106.35 ? 616 LEU A CA  1 
ATOM   4044  C C   . LEU A 1 616 ? 154.972 131.136 172.912 1.00 106.12 ? 616 LEU A C   1 
ATOM   4045  O O   . LEU A 1 616 ? 154.969 132.352 172.735 1.00 107.10 ? 616 LEU A O   1 
ATOM   4046  C CB  . LEU A 1 616 ? 153.108 130.048 171.585 1.00 104.60 ? 616 LEU A CB  1 
ATOM   4047  C CG  . LEU A 1 616 ? 151.819 129.211 171.533 1.00 104.31 ? 616 LEU A CG  1 
ATOM   4048  C CD1 . LEU A 1 616 ? 151.454 128.924 170.080 1.00 101.63 ? 616 LEU A CD1 1 
ATOM   4049  C CD2 . LEU A 1 616 ? 151.968 127.874 172.253 1.00 104.26 ? 616 LEU A CD2 1 
ATOM   4050  N N   . ARG A 1 617 ? 156.122 130.451 172.971 1.00 95.70  ? 617 ARG A N   1 
ATOM   4051  C CA  . ARG A 1 617 ? 157.452 131.133 172.914 1.00 95.42  ? 617 ARG A CA  1 
ATOM   4052  C C   . ARG A 1 617 ? 157.680 131.720 171.529 1.00 97.10  ? 617 ARG A C   1 
ATOM   4053  O O   . ARG A 1 617 ? 158.163 132.854 171.455 1.00 91.06  ? 617 ARG A O   1 
ATOM   4054  C CB  . ARG A 1 617 ? 158.566 130.133 173.222 1.00 90.97  ? 617 ARG A CB  1 
ATOM   4055  C CG  . ARG A 1 617 ? 159.947 130.738 173.419 1.00 90.08  ? 617 ARG A CG  1 
ATOM   4056  C CD  . ARG A 1 617 ? 160.942 129.598 173.507 1.00 95.52  ? 617 ARG A CD  1 
ATOM   4057  N NE  . ARG A 1 617 ? 162.179 129.874 174.223 1.00 98.54  ? 617 ARG A NE  1 
ATOM   4058  C CZ  . ARG A 1 617 ? 163.294 130.332 173.667 1.00 98.75  ? 617 ARG A CZ  1 
ATOM   4059  N NH1 . ARG A 1 617 ? 164.366 130.539 174.411 1.00 96.79  ? 617 ARG A NH1 1 
ATOM   4060  N NH2 . ARG A 1 617 ? 163.336 130.591 172.374 1.00 98.63  ? 617 ARG A NH2 1 
ATOM   4061  N N   . PHE A 1 618 ? 157.351 130.970 170.481 1.00 96.62  ? 618 PHE A N   1 
ATOM   4062  C CA  . PHE A 1 618 ? 157.514 131.342 169.073 1.00 90.72  ? 618 PHE A CA  1 
ATOM   4063  C C   . PHE A 1 618 ? 156.221 131.902 168.455 1.00 92.95  ? 618 PHE A C   1 
ATOM   4064  O O   . PHE A 1 618 ? 155.943 131.674 167.281 1.00 95.13  ? 618 PHE A O   1 
ATOM   4065  C CB  . PHE A 1 618 ? 158.069 130.136 168.302 1.00 89.94  ? 618 PHE A CB  1 
ATOM   4066  C CG  . PHE A 1 618 ? 159.380 129.601 168.840 1.00 89.91  ? 618 PHE A CG  1 
ATOM   4067  C CD1 . PHE A 1 618 ? 160.562 130.344 168.685 1.00 86.79  ? 618 PHE A CD1 1 
ATOM   4068  C CD2 . PHE A 1 618 ? 159.416 128.371 169.514 1.00 89.34  ? 618 PHE A CD2 1 
ATOM   4069  C CE1 . PHE A 1 618 ? 161.769 129.869 169.221 1.00 84.37  ? 618 PHE A CE1 1 
ATOM   4070  C CE2 . PHE A 1 618 ? 160.621 127.899 170.053 1.00 90.64  ? 618 PHE A CE2 1 
ATOM   4071  C CZ  . PHE A 1 618 ? 161.798 128.644 169.906 1.00 88.47  ? 618 PHE A CZ  1 
ATOM   4072  N N   . ARG A 1 619 ? 155.381 132.588 169.232 1.00 102.49 ? 619 ARG A N   1 
ATOM   4073  C CA  . ARG A 1 619 ? 154.034 133.054 168.773 1.00 97.93  ? 619 ARG A CA  1 
ATOM   4074  C C   . ARG A 1 619 ? 154.038 133.898 167.493 1.00 96.19  ? 619 ARG A C   1 
ATOM   4075  O O   . ARG A 1 619 ? 153.028 133.857 166.796 1.00 97.02  ? 619 ARG A O   1 
ATOM   4076  C CB  . ARG A 1 619 ? 153.370 133.837 169.906 1.00 102.06 ? 619 ARG A CB  1 
ATOM   4077  C CG  . ARG A 1 619 ? 154.075 135.133 170.274 1.00 100.28 ? 619 ARG A CG  1 
ATOM   4078  C CD  . ARG A 1 619 ? 153.558 135.675 171.588 1.00 100.09 ? 619 ARG A CD  1 
ATOM   4079  N NE  . ARG A 1 619 ? 154.351 136.808 172.036 1.00 103.79 ? 619 ARG A NE  1 
ATOM   4080  C CZ  . ARG A 1 619 ? 154.208 137.402 173.213 1.00 102.50 ? 619 ARG A CZ  1 
ATOM   4081  N NH1 . ARG A 1 619 ? 154.975 138.431 173.530 1.00 98.34  ? 619 ARG A NH1 1 
ATOM   4082  N NH2 . ARG A 1 619 ? 153.304 136.964 174.069 1.00 100.97 ? 619 ARG A NH2 1 
ATOM   4083  N N   . GLY A 1 620 ? 155.050 134.712 167.240 1.00 83.47  ? 620 GLY A N   1 
ATOM   4084  C CA  . GLY A 1 620 ? 155.160 135.435 165.972 1.00 87.03  ? 620 GLY A CA  1 
ATOM   4085  C C   . GLY A 1 620 ? 155.434 134.518 164.780 1.00 87.54  ? 620 GLY A C   1 
ATOM   4086  O O   . GLY A 1 620 ? 154.888 134.723 163.702 1.00 84.70  ? 620 GLY A O   1 
ATOM   4087  N N   . VAL A 1 621 ? 156.223 133.460 164.967 1.00 88.88  ? 621 VAL A N   1 
ATOM   4088  C CA  . VAL A 1 621 ? 156.515 132.478 163.913 1.00 86.75  ? 621 VAL A CA  1 
ATOM   4089  C C   . VAL A 1 621 ? 155.317 131.559 163.678 1.00 83.70  ? 621 VAL A C   1 
ATOM   4090  O O   . VAL A 1 621 ? 154.999 131.260 162.536 1.00 86.47  ? 621 VAL A O   1 
ATOM   4091  C CB  . VAL A 1 621 ? 157.784 131.664 164.215 1.00 85.17  ? 621 VAL A CB  1 
ATOM   4092  C CG1 . VAL A 1 621 ? 158.182 130.841 162.988 1.00 84.69  ? 621 VAL A CG1 1 
ATOM   4093  C CG2 . VAL A 1 621 ? 158.982 132.547 164.574 1.00 87.41  ? 621 VAL A CG2 1 
ATOM   4094  N N   . VAL A 1 622 ? 154.594 131.171 164.730 1.00 79.29  ? 622 VAL A N   1 
ATOM   4095  C CA  . VAL A 1 622 ? 153.315 130.450 164.619 1.00 77.91  ? 622 VAL A CA  1 
ATOM   4096  C C   . VAL A 1 622 ? 152.283 131.280 163.846 1.00 81.86  ? 622 VAL A C   1 
ATOM   4097  O O   . VAL A 1 622 ? 151.667 130.755 162.927 1.00 86.44  ? 622 VAL A O   1 
ATOM   4098  C CB  . VAL A 1 622 ? 152.808 130.022 166.009 1.00 77.61  ? 622 VAL A CB  1 
ATOM   4099  C CG1 . VAL A 1 622 ? 151.397 129.458 166.003 1.00 74.93  ? 622 VAL A CG1 1 
ATOM   4100  C CG2 . VAL A 1 622 ? 153.714 128.943 166.596 1.00 82.01  ? 622 VAL A CG2 1 
ATOM   4101  N N   . LEU A 1 623 ? 152.137 132.584 164.117 1.00 82.46  ? 623 LEU A N   1 
ATOM   4102  C CA  . LEU A 1 623 ? 151.277 133.469 163.323 1.00 77.19  ? 623 LEU A CA  1 
ATOM   4103  C C   . LEU A 1 623 ? 151.748 133.605 161.862 1.00 81.14  ? 623 LEU A C   1 
ATOM   4104  O O   . LEU A 1 623 ? 150.927 133.526 160.952 1.00 83.16  ? 623 LEU A O   1 
ATOM   4105  C CB  . LEU A 1 623 ? 151.161 134.834 164.021 1.00 80.30  ? 623 LEU A CB  1 
ATOM   4106  C CG  . LEU A 1 623 ? 150.321 135.868 163.252 1.00 84.94  ? 623 LEU A CG  1 
ATOM   4107  C CD1 . LEU A 1 623 ? 148.873 135.429 163.085 1.00 85.90  ? 623 LEU A CD1 1 
ATOM   4108  C CD2 . LEU A 1 623 ? 150.328 137.209 163.973 1.00 84.90  ? 623 LEU A CD2 1 
ATOM   4109  N N   . LEU A 1 624 ? 153.045 133.753 161.595 1.00 82.30  ? 624 LEU A N   1 
ATOM   4110  C CA  . LEU A 1 624 ? 153.568 133.741 160.226 1.00 80.87  ? 624 LEU A CA  1 
ATOM   4111  C C   . LEU A 1 624 ? 153.328 132.403 159.507 1.00 85.10  ? 624 LEU A C   1 
ATOM   4112  O O   . LEU A 1 624 ? 153.030 132.425 158.318 1.00 89.23  ? 624 LEU A O   1 
ATOM   4113  C CB  . LEU A 1 624 ? 155.060 134.100 160.230 1.00 82.26  ? 624 LEU A CB  1 
ATOM   4114  C CG  . LEU A 1 624 ? 155.340 135.582 160.521 1.00 84.71  ? 624 LEU A CG  1 
ATOM   4115  C CD1 . LEU A 1 624 ? 156.815 135.779 160.856 1.00 83.82  ? 624 LEU A CD1 1 
ATOM   4116  C CD2 . LEU A 1 624 ? 155.007 136.461 159.319 1.00 82.11  ? 624 LEU A CD2 1 
ATOM   4117  N N   . LEU A 1 625 ? 153.391 131.251 160.187 1.00 74.77  ? 625 LEU A N   1 
ATOM   4118  C CA  . LEU A 1 625 ? 153.011 129.960 159.608 1.00 69.72  ? 625 LEU A CA  1 
ATOM   4119  C C   . LEU A 1 625 ? 151.524 129.895 159.257 1.00 79.57  ? 625 LEU A C   1 
ATOM   4120  O O   . LEU A 1 625 ? 151.184 129.373 158.202 1.00 89.46  ? 625 LEU A O   1 
ATOM   4121  C CB  . LEU A 1 625 ? 153.365 128.809 160.557 1.00 72.98  ? 625 LEU A CB  1 
ATOM   4122  C CG  . LEU A 1 625 ? 154.837 128.385 160.565 1.00 82.33  ? 625 LEU A CG  1 
ATOM   4123  C CD1 . LEU A 1 625 ? 155.043 127.281 161.586 1.00 77.69  ? 625 LEU A CD1 1 
ATOM   4124  C CD2 . LEU A 1 625 ? 155.277 127.836 159.216 1.00 79.18  ? 625 LEU A CD2 1 
ATOM   4125  N N   . LEU A 1 626 ? 150.630 130.446 160.082 1.00 74.79  ? 626 LEU A N   1 
ATOM   4126  C CA  . LEU A 1 626 ? 149.210 130.546 159.728 1.00 66.02  ? 626 LEU A CA  1 
ATOM   4127  C C   . LEU A 1 626 ? 148.983 131.491 158.551 1.00 68.15  ? 626 LEU A C   1 
ATOM   4128  O O   . LEU A 1 626 ? 148.248 131.144 157.638 1.00 70.25  ? 626 LEU A O   1 
ATOM   4129  C CB  . LEU A 1 626 ? 148.374 131.015 160.921 1.00 66.93  ? 626 LEU A CB  1 
ATOM   4130  C CG  . LEU A 1 626 ? 148.347 130.057 162.111 1.00 71.44  ? 626 LEU A CG  1 
ATOM   4131  C CD1 . LEU A 1 626 ? 147.640 130.740 163.274 1.00 68.35  ? 626 LEU A CD1 1 
ATOM   4132  C CD2 . LEU A 1 626 ? 147.615 128.765 161.770 1.00 67.91  ? 626 LEU A CD2 1 
ATOM   4133  N N   . LEU A 1 627 ? 149.621 132.661 158.519 1.00 71.49  ? 627 LEU A N   1 
ATOM   4134  C CA  . LEU A 1 627 ? 149.507 133.599 157.398 1.00 69.99  ? 627 LEU A CA  1 
ATOM   4135  C C   . LEU A 1 627 ? 150.084 133.022 156.102 1.00 71.65  ? 627 LEU A C   1 
ATOM   4136  O O   . LEU A 1 627 ? 149.499 133.208 155.043 1.00 73.92  ? 627 LEU A O   1 
ATOM   4137  C CB  . LEU A 1 627 ? 150.184 134.930 157.759 1.00 70.80  ? 627 LEU A CB  1 
ATOM   4138  C CG  . LEU A 1 627 ? 149.450 135.735 158.843 1.00 69.43  ? 627 LEU A CG  1 
ATOM   4139  C CD1 . LEU A 1 627 ? 150.312 136.917 159.263 1.00 69.66  ? 627 LEU A CD1 1 
ATOM   4140  C CD2 . LEU A 1 627 ? 148.115 136.271 158.344 1.00 72.81  ? 627 LEU A CD2 1 
ATOM   4141  N N   . ALA A 1 628 ? 151.179 132.265 156.166 1.00 74.27  ? 628 ALA A N   1 
ATOM   4142  C CA  . ALA A 1 628 ? 151.673 131.483 155.040 1.00 66.60  ? 628 ALA A CA  1 
ATOM   4143  C C   . ALA A 1 628 ? 150.662 130.424 154.592 1.00 70.31  ? 628 ALA A C   1 
ATOM   4144  O O   . ALA A 1 628 ? 150.330 130.389 153.412 1.00 76.15  ? 628 ALA A O   1 
ATOM   4145  C CB  . ALA A 1 628 ? 153.012 130.859 155.424 1.00 61.38  ? 628 ALA A CB  1 
ATOM   4146  N N   . TYR A 1 629 ? 150.089 129.617 155.491 1.00 58.50  ? 629 TYR A N   1 
ATOM   4147  C CA  . TYR A 1 629 ? 149.068 128.630 155.118 1.00 56.25  ? 629 TYR A CA  1 
ATOM   4148  C C   . TYR A 1 629 ? 147.832 129.277 154.491 1.00 62.59  ? 629 TYR A C   1 
ATOM   4149  O O   . TYR A 1 629 ? 147.379 128.816 153.445 1.00 73.34  ? 629 TYR A O   1 
ATOM   4150  C CB  . TYR A 1 629 ? 148.681 127.765 156.324 1.00 58.50  ? 629 TYR A CB  1 
ATOM   4151  C CG  . TYR A 1 629 ? 147.454 126.895 156.102 1.00 58.38  ? 629 TYR A CG  1 
ATOM   4152  C CD1 . TYR A 1 629 ? 147.545 125.656 155.433 1.00 54.72  ? 629 TYR A CD1 1 
ATOM   4153  C CD2 . TYR A 1 629 ? 146.204 127.356 156.540 1.00 60.10  ? 629 TYR A CD2 1 
ATOM   4154  C CE1 . TYR A 1 629 ? 146.385 124.894 155.189 1.00 56.62  ? 629 TYR A CE1 1 
ATOM   4155  C CE2 . TYR A 1 629 ? 145.051 126.594 156.305 1.00 67.78  ? 629 TYR A CE2 1 
ATOM   4156  C CZ  . TYR A 1 629 ? 145.125 125.366 155.621 1.00 69.10  ? 629 TYR A CZ  1 
ATOM   4157  O OH  . TYR A 1 629 ? 143.983 124.647 155.423 1.00 58.80  ? 629 TYR A OH  1 
ATOM   4158  N N   . VAL A 1 630 ? 147.294 130.350 155.073 1.00 63.56  ? 630 VAL A N   1 
ATOM   4159  C CA  . VAL A 1 630 ? 146.111 131.064 154.558 1.00 64.99  ? 630 VAL A CA  1 
ATOM   4160  C C   . VAL A 1 630 ? 146.358 131.586 153.156 1.00 62.84  ? 630 VAL A C   1 
ATOM   4161  O O   . VAL A 1 630 ? 145.583 131.306 152.250 1.00 66.65  ? 630 VAL A O   1 
ATOM   4162  C CB  . VAL A 1 630 ? 145.721 132.218 155.499 1.00 64.10  ? 630 VAL A CB  1 
ATOM   4163  C CG1 . VAL A 1 630 ? 144.705 133.189 154.893 1.00 61.26  ? 630 VAL A CG1 1 
ATOM   4164  C CG2 . VAL A 1 630 ? 145.083 131.666 156.767 1.00 63.37  ? 630 VAL A CG2 1 
ATOM   4165  N N   . LEU A 1 631 ? 147.451 132.321 152.939 1.00 66.46  ? 631 LEU A N   1 
ATOM   4166  C CA  . LEU A 1 631 ? 147.749 132.899 151.640 1.00 65.30  ? 631 LEU A CA  1 
ATOM   4167  C C   . LEU A 1 631 ? 147.989 131.814 150.595 1.00 66.00  ? 631 LEU A C   1 
ATOM   4168  O O   . LEU A 1 631 ? 147.366 131.855 149.541 1.00 70.06  ? 631 LEU A O   1 
ATOM   4169  C CB  . LEU A 1 631 ? 148.925 133.878 151.780 1.00 65.07  ? 631 LEU A CB  1 
ATOM   4170  C CG  . LEU A 1 631 ? 148.578 135.137 152.598 1.00 67.40  ? 631 LEU A CG  1 
ATOM   4171  C CD1 . LEU A 1 631 ? 149.838 135.949 152.861 1.00 69.73  ? 631 LEU A CD1 1 
ATOM   4172  C CD2 . LEU A 1 631 ? 147.596 136.045 151.871 1.00 65.19  ? 631 LEU A CD2 1 
ATOM   4173  N N   . LEU A 1 632 ? 148.794 130.788 150.885 1.00 67.20  ? 632 LEU A N   1 
ATOM   4174  C CA  . LEU A 1 632 ? 149.013 129.683 149.953 1.00 60.01  ? 632 LEU A CA  1 
ATOM   4175  C C   . LEU A 1 632 ? 147.734 128.909 149.640 1.00 58.09  ? 632 LEU A C   1 
ATOM   4176  O O   . LEU A 1 632 ? 147.486 128.582 148.485 1.00 68.09  ? 632 LEU A O   1 
ATOM   4177  C CB  . LEU A 1 632 ? 150.074 128.731 150.515 1.00 60.36  ? 632 LEU A CB  1 
ATOM   4178  C CG  . LEU A 1 632 ? 151.493 129.314 150.566 1.00 64.17  ? 632 LEU A CG  1 
ATOM   4179  C CD1 . LEU A 1 632 ? 152.426 128.256 151.143 1.00 65.19  ? 632 LEU A CD1 1 
ATOM   4180  C CD2 . LEU A 1 632 ? 152.013 129.699 149.187 1.00 64.52  ? 632 LEU A CD2 1 
ATOM   4181  N N   . THR A 1 633 ? 146.896 128.640 150.632 1.00 59.95  ? 633 THR A N   1 
ATOM   4182  C CA  . THR A 1 633 ? 145.622 127.930 150.462 1.00 62.05  ? 633 THR A CA  1 
ATOM   4183  C C   . THR A 1 633 ? 144.600 128.746 149.685 1.00 63.65  ? 633 THR A C   1 
ATOM   4184  O O   . THR A 1 633 ? 143.876 128.189 148.875 1.00 62.93  ? 633 THR A O   1 
ATOM   4185  C CB  . THR A 1 633 ? 145.040 127.554 151.824 1.00 57.87  ? 633 THR A CB  1 
ATOM   4186  O OG1 . THR A 1 633 ? 145.947 126.702 152.459 1.00 66.25  ? 633 THR A OG1 1 
ATOM   4187  C CG2 . THR A 1 633 ? 143.705 126.828 151.756 1.00 62.48  ? 633 THR A CG2 1 
ATOM   4188  N N   . TYR A 1 634 ? 144.514 130.059 149.882 1.00 73.12  ? 634 TYR A N   1 
ATOM   4189  C CA  . TYR A 1 634 ? 143.540 130.880 149.167 1.00 59.43  ? 634 TYR A CA  1 
ATOM   4190  C C   . TYR A 1 634 ? 144.005 131.156 147.732 1.00 65.11  ? 634 TYR A C   1 
ATOM   4191  O O   . TYR A 1 634 ? 143.180 131.151 146.829 1.00 71.64  ? 634 TYR A O   1 
ATOM   4192  C CB  . TYR A 1 634 ? 143.219 132.149 149.970 1.00 65.97  ? 634 TYR A CB  1 
ATOM   4193  C CG  . TYR A 1 634 ? 142.306 131.971 151.187 1.00 83.64  ? 634 TYR A CG  1 
ATOM   4194  C CD1 . TYR A 1 634 ? 142.193 130.747 151.880 1.00 81.25  ? 634 TYR A CD1 1 
ATOM   4195  C CD2 . TYR A 1 634 ? 141.532 133.061 151.623 1.00 73.69  ? 634 TYR A CD2 1 
ATOM   4196  C CE1 . TYR A 1 634 ? 141.330 130.608 152.976 1.00 73.79  ? 634 TYR A CE1 1 
ATOM   4197  C CE2 . TYR A 1 634 ? 140.661 132.923 152.716 1.00 71.23  ? 634 TYR A CE2 1 
ATOM   4198  C CZ  . TYR A 1 634 ? 140.554 131.692 153.399 1.00 74.15  ? 634 TYR A CZ  1 
ATOM   4199  O OH  . TYR A 1 634 ? 139.700 131.559 154.450 1.00 78.69  ? 634 TYR A OH  1 
ATOM   4200  N N   . VAL A 1 635 ? 145.311 131.261 147.467 1.00 68.64  ? 635 VAL A N   1 
ATOM   4201  C CA  . VAL A 1 635 ? 145.880 131.194 146.111 1.00 59.30  ? 635 VAL A CA  1 
ATOM   4202  C C   . VAL A 1 635 ? 145.579 129.846 145.445 1.00 59.44  ? 635 VAL A C   1 
ATOM   4203  O O   . VAL A 1 635 ? 145.161 129.819 144.294 1.00 68.21  ? 635 VAL A O   1 
ATOM   4204  C CB  . VAL A 1 635 ? 147.395 131.462 146.143 1.00 58.68  ? 635 VAL A CB  1 
ATOM   4205  C CG1 . VAL A 1 635 ? 148.080 131.254 144.794 1.00 67.70  ? 635 VAL A CG1 1 
ATOM   4206  C CG2 . VAL A 1 635 ? 147.678 132.907 146.540 1.00 58.60  ? 635 VAL A CG2 1 
ATOM   4207  N N   . LEU A 1 636 ? 145.724 128.721 146.151 1.00 52.16  ? 636 LEU A N   1 
ATOM   4208  C CA  . LEU A 1 636 ? 145.361 127.398 145.642 1.00 53.13  ? 636 LEU A CA  1 
ATOM   4209  C C   . LEU A 1 636 ? 143.860 127.279 145.341 1.00 60.50  ? 636 LEU A C   1 
ATOM   4210  O O   . LEU A 1 636 ? 143.512 126.800 144.267 1.00 71.99  ? 636 LEU A O   1 
ATOM   4211  C CB  . LEU A 1 636 ? 145.842 126.330 146.634 1.00 64.45  ? 636 LEU A CB  1 
ATOM   4212  C CG  . LEU A 1 636 ? 145.387 124.899 146.318 1.00 69.83  ? 636 LEU A CG  1 
ATOM   4213  C CD1 . LEU A 1 636 ? 146.024 124.369 145.039 1.00 61.35  ? 636 LEU A CD1 1 
ATOM   4214  C CD2 . LEU A 1 636 ? 145.735 123.980 147.481 1.00 62.85  ? 636 LEU A CD2 1 
ATOM   4215  N N   . LEU A 1 637 ? 142.962 127.710 146.221 1.00 62.63  ? 637 LEU A N   1 
ATOM   4216  C CA  . LEU A 1 637 ? 141.516 127.679 145.967 1.00 58.81  ? 637 LEU A CA  1 
ATOM   4217  C C   . LEU A 1 637 ? 141.130 128.585 144.794 1.00 58.59  ? 637 LEU A C   1 
ATOM   4218  O O   . LEU A 1 637 ? 140.289 128.215 143.994 1.00 63.27  ? 637 LEU A O   1 
ATOM   4219  C CB  . LEU A 1 637 ? 140.741 128.068 147.234 1.00 65.31  ? 637 LEU A CB  1 
ATOM   4220  C CG  . LEU A 1 637 ? 140.785 127.033 148.370 1.00 68.45  ? 637 LEU A CG  1 
ATOM   4221  C CD1 . LEU A 1 637 ? 140.171 127.622 149.636 1.00 65.09  ? 637 LEU A CD1 1 
ATOM   4222  C CD2 . LEU A 1 637 ? 140.013 125.766 148.023 1.00 65.47  ? 637 LEU A CD2 1 
ATOM   4223  N N   . LEU A 1 638 ? 141.772 129.742 144.642 1.00 67.72  ? 638 LEU A N   1 
ATOM   4224  C CA  . LEU A 1 638 ? 141.600 130.654 143.516 1.00 61.59  ? 638 LEU A CA  1 
ATOM   4225  C C   . LEU A 1 638 ? 142.083 130.036 142.191 1.00 62.02  ? 638 LEU A C   1 
ATOM   4226  O O   . LEU A 1 638 ? 141.347 130.052 141.212 1.00 63.36  ? 638 LEU A O   1 
ATOM   4227  C CB  . LEU A 1 638 ? 142.327 131.949 143.905 1.00 62.84  ? 638 LEU A CB  1 
ATOM   4228  C CG  . LEU A 1 638 ? 142.235 133.143 142.957 1.00 65.56  ? 638 LEU A CG  1 
ATOM   4229  C CD1 . LEU A 1 638 ? 140.797 133.610 142.774 1.00 62.24  ? 638 LEU A CD1 1 
ATOM   4230  C CD2 . LEU A 1 638 ? 143.049 134.275 143.576 1.00 64.21  ? 638 LEU A CD2 1 
ATOM   4231  N N   . ASN A 1 639 ? 143.252 129.389 142.172 1.00 73.09  ? 639 ASN A N   1 
ATOM   4232  C CA  . ASN A 1 639 ? 143.722 128.573 141.048 1.00 63.16  ? 639 ASN A CA  1 
ATOM   4233  C C   . ASN A 1 639 ? 142.757 127.424 140.725 1.00 64.07  ? 639 ASN A C   1 
ATOM   4234  O O   . ASN A 1 639 ? 142.490 127.164 139.558 1.00 75.44  ? 639 ASN A O   1 
ATOM   4235  C CB  . ASN A 1 639 ? 145.105 127.967 141.349 1.00 57.18  ? 639 ASN A CB  1 
ATOM   4236  C CG  . ASN A 1 639 ? 146.277 128.926 141.418 1.00 66.19  ? 639 ASN A CG  1 
ATOM   4237  O OD1 . ASN A 1 639 ? 146.220 130.071 141.021 1.00 68.69  ? 639 ASN A OD1 1 
ATOM   4238  N ND2 . ASN A 1 639 ? 147.402 128.480 141.921 1.00 68.68  ? 639 ASN A ND2 1 
ATOM   4239  N N   . MET A 1 640 ? 142.226 126.730 141.732 1.00 59.81  ? 640 MET A N   1 
ATOM   4240  C CA  . MET A 1 640 ? 141.317 125.598 141.566 1.00 59.69  ? 640 MET A CA  1 
ATOM   4241  C C   . MET A 1 640 ? 139.967 126.007 140.970 1.00 68.16  ? 640 MET A C   1 
ATOM   4242  O O   . MET A 1 640 ? 139.544 125.410 139.989 1.00 70.22  ? 640 MET A O   1 
ATOM   4243  C CB  . MET A 1 640 ? 141.175 124.883 142.915 1.00 65.54  ? 640 MET A CB  1 
ATOM   4244  C CG  . MET A 1 640 ? 140.315 123.617 142.871 1.00 69.39  ? 640 MET A CG  1 
ATOM   4245  S SD  . MET A 1 640 ? 138.565 123.781 143.286 1.00 82.07  ? 640 MET A SD  1 
ATOM   4246  C CE  . MET A 1 640 ? 138.652 124.215 145.039 1.00 66.57  ? 640 MET A CE  1 
ATOM   4247  N N   . LEU A 1 641 ? 139.328 127.069 141.467 1.00 72.65  ? 641 LEU A N   1 
ATOM   4248  C CA  . LEU A 1 641 ? 138.070 127.583 140.914 1.00 64.10  ? 641 LEU A CA  1 
ATOM   4249  C C   . LEU A 1 641 ? 138.245 128.075 139.477 1.00 61.28  ? 641 LEU A C   1 
ATOM   4250  O O   . LEU A 1 641 ? 137.437 127.751 138.615 1.00 69.04  ? 641 LEU A O   1 
ATOM   4251  C CB  . LEU A 1 641 ? 137.529 128.709 141.812 1.00 70.89  ? 641 LEU A CB  1 
ATOM   4252  C CG  . LEU A 1 641 ? 136.465 128.249 142.823 1.00 72.69  ? 641 LEU A CG  1 
ATOM   4253  C CD1 . LEU A 1 641 ? 136.925 127.139 143.758 1.00 63.71  ? 641 LEU A CD1 1 
ATOM   4254  C CD2 . LEU A 1 641 ? 136.054 129.437 143.687 1.00 73.43  ? 641 LEU A CD2 1 
ATOM   4255  N N   . ILE A 1 642 ? 139.301 128.825 139.183 1.00 67.07  ? 642 ILE A N   1 
ATOM   4256  C CA  . ILE A 1 642 ? 139.574 129.321 137.829 1.00 67.49  ? 642 ILE A CA  1 
ATOM   4257  C C   . ILE A 1 642 ? 139.930 128.190 136.862 1.00 67.35  ? 642 ILE A C   1 
ATOM   4258  O O   . ILE A 1 642 ? 139.461 128.205 135.726 1.00 76.05  ? 642 ILE A O   1 
ATOM   4259  C CB  . ILE A 1 642 ? 140.624 130.446 137.907 1.00 68.91  ? 642 ILE A CB  1 
ATOM   4260  C CG1 . ILE A 1 642 ? 139.913 131.724 138.410 1.00 66.91  ? 642 ILE A CG1 1 
ATOM   4261  C CG2 . ILE A 1 642 ? 141.302 130.707 136.562 1.00 65.81  ? 642 ILE A CG2 1 
ATOM   4262  C CD1 . ILE A 1 642 ? 140.844 132.801 138.954 1.00 67.10  ? 642 ILE A CD1 1 
ATOM   4263  N N   . ALA A 1 643 ? 140.679 127.167 137.284 1.00 65.94  ? 643 ALA A N   1 
ATOM   4264  C CA  . ALA A 1 643 ? 140.917 125.968 136.484 1.00 61.18  ? 643 ALA A CA  1 
ATOM   4265  C C   . ALA A 1 643 ? 139.603 125.243 136.145 1.00 70.60  ? 643 ALA A C   1 
ATOM   4266  O O   . ALA A 1 643 ? 139.353 124.972 134.973 1.00 80.51  ? 643 ALA A O   1 
ATOM   4267  C CB  . ALA A 1 643 ? 141.902 125.060 137.217 1.00 57.77  ? 643 ALA A CB  1 
ATOM   4268  N N   . LEU A 1 644 ? 138.721 125.013 137.121 1.00 78.52  ? 644 LEU A N   1 
ATOM   4269  C CA  . LEU A 1 644 ? 137.397 124.424 136.905 1.00 69.82  ? 644 LEU A CA  1 
ATOM   4270  C C   . LEU A 1 644 ? 136.526 125.260 135.963 1.00 69.75  ? 644 LEU A C   1 
ATOM   4271  O O   . LEU A 1 644 ? 135.952 124.699 135.035 1.00 82.17  ? 644 LEU A O   1 
ATOM   4272  C CB  . LEU A 1 644 ? 136.687 124.232 138.253 1.00 72.86  ? 644 LEU A CB  1 
ATOM   4273  C CG  . LEU A 1 644 ? 136.798 122.817 138.837 1.00 77.22  ? 644 LEU A CG  1 
ATOM   4274  C CD1 . LEU A 1 644 ? 138.226 122.309 138.996 1.00 78.40  ? 644 LEU A CD1 1 
ATOM   4275  C CD2 . LEU A 1 644 ? 136.156 122.816 140.215 1.00 78.76  ? 644 LEU A CD2 1 
ATOM   4276  N N   . MET A 1 645 ? 136.437 126.581 136.132 1.00 72.92  ? 645 MET A N   1 
ATOM   4277  C CA  . MET A 1 645 ? 135.710 127.443 135.189 1.00 76.95  ? 645 MET A CA  1 
ATOM   4278  C C   . MET A 1 645 ? 136.264 127.329 133.772 1.00 81.17  ? 645 MET A C   1 
ATOM   4279  O O   . MET A 1 645 ? 135.496 127.199 132.830 1.00 83.06  ? 645 MET A O   1 
ATOM   4280  C CB  . MET A 1 645 ? 135.768 128.909 135.618 1.00 74.40  ? 645 MET A CB  1 
ATOM   4281  C CG  . MET A 1 645 ? 134.964 129.184 136.882 1.00 81.85  ? 645 MET A CG  1 
ATOM   4282  S SD  . MET A 1 645 ? 135.155 130.878 137.466 1.00 94.00  ? 645 MET A SD  1 
ATOM   4283  C CE  . MET A 1 645 ? 134.536 130.632 139.147 1.00 82.05  ? 645 MET A CE  1 
ATOM   4284  N N   . SER A 1 646 ? 137.585 127.328 133.602 1.00 81.89  ? 646 SER A N   1 
ATOM   4285  C CA  . SER A 1 646 ? 138.197 127.256 132.275 1.00 81.03  ? 646 SER A CA  1 
ATOM   4286  C C   . SER A 1 646 ? 137.826 125.986 131.492 1.00 85.15  ? 646 SER A C   1 
ATOM   4287  O O   . SER A 1 646 ? 137.623 126.070 130.283 1.00 87.16  ? 646 SER A O   1 
ATOM   4288  C CB  . SER A 1 646 ? 139.713 127.428 132.382 1.00 76.66  ? 646 SER A CB  1 
ATOM   4289  O OG  . SER A 1 646 ? 140.369 126.248 132.807 1.00 78.96  ? 646 SER A OG  1 
ATOM   4290  N N   . GLU A 1 647 ? 137.681 124.821 132.138 1.00 90.30  ? 647 GLU A N   1 
ATOM   4291  C CA  . GLU A 1 647 ? 137.246 123.600 131.445 1.00 92.76  ? 647 GLU A CA  1 
ATOM   4292  C C   . GLU A 1 647 ? 135.719 123.475 131.337 1.00 94.62  ? 647 GLU A C   1 
ATOM   4293  O O   . GLU A 1 647 ? 135.213 123.046 130.303 1.00 99.01  ? 647 GLU A O   1 
ATOM   4294  C CB  . GLU A 1 647 ? 137.876 122.352 132.087 1.00 92.30  ? 647 GLU A CB  1 
ATOM   4295  C CG  . GLU A 1 647 ? 137.555 121.086 131.256 1.00 101.30 ? 647 GLU A CG  1 
ATOM   4296  C CD  . GLU A 1 647 ? 138.500 119.889 131.470 1.00 103.04 ? 647 GLU A CD  1 
ATOM   4297  O OE1 . GLU A 1 647 ? 139.625 120.054 131.985 1.00 98.81  ? 647 GLU A OE1 1 
ATOM   4298  O OE2 . GLU A 1 647 ? 138.129 118.742 131.145 1.00 99.26  ? 647 GLU A OE2 1 
ATOM   4299  N N   . THR A 1 648 ? 134.971 123.837 132.378 1.00 78.23  ? 648 THR A N   1 
ATOM   4300  C CA  . THR A 1 648 ? 133.521 123.577 132.461 1.00 80.26  ? 648 THR A CA  1 
ATOM   4301  C C   . THR A 1 648 ? 132.621 124.692 131.912 1.00 80.71  ? 648 THR A C   1 
ATOM   4302  O O   . THR A 1 648 ? 131.476 124.414 131.570 1.00 81.80  ? 648 THR A O   1 
ATOM   4303  C CB  . THR A 1 648 ? 133.092 123.243 133.896 1.00 78.59  ? 648 THR A CB  1 
ATOM   4304  O OG1 . THR A 1 648 ? 133.349 124.319 134.754 1.00 81.80  ? 648 THR A OG1 1 
ATOM   4305  C CG2 . THR A 1 648 ? 133.778 122.011 134.476 1.00 75.32  ? 648 THR A CG2 1 
ATOM   4306  N N   . VAL A 1 649 ? 133.092 125.937 131.792 1.00 82.30  ? 649 VAL A N   1 
ATOM   4307  C CA  . VAL A 1 649 ? 132.290 127.053 131.214 1.00 83.41  ? 649 VAL A CA  1 
ATOM   4308  C C   . VAL A 1 649 ? 132.782 127.212 129.781 1.00 87.67  ? 649 VAL A C   1 
ATOM   4309  O O   . VAL A 1 649 ? 133.494 128.198 129.502 1.00 87.26  ? 649 VAL A O   1 
ATOM   4310  C CB  . VAL A 1 649 ? 132.447 128.352 132.028 1.00 79.62  ? 649 VAL A CB  1 
ATOM   4311  C CG1 . VAL A 1 649 ? 131.504 129.441 131.537 1.00 79.31  ? 649 VAL A CG1 1 
ATOM   4312  C CG2 . VAL A 1 649 ? 132.247 128.107 133.516 1.00 80.95  ? 649 VAL A CG2 1 
ATOM   4313  N N   . ASN A 1 650 ? 132.427 126.263 128.917 1.00 90.51  ? 650 ASN A N   1 
ATOM   4314  C CA  . ASN A 1 650 ? 132.993 126.286 127.545 1.00 87.40  ? 650 ASN A CA  1 
ATOM   4315  C C   . ASN A 1 650 ? 131.950 126.697 126.503 1.00 86.89  ? 650 ASN A C   1 
ATOM   4316  O O   . ASN A 1 650 ? 132.376 126.866 125.343 1.00 84.00  ? 650 ASN A O   1 
ATOM   4317  C CB  . ASN A 1 650 ? 133.609 124.932 127.185 1.00 90.41  ? 650 ASN A CB  1 
ATOM   4318  C CG  . ASN A 1 650 ? 132.661 123.777 127.429 1.00 94.30  ? 650 ASN A CG  1 
ATOM   4319  O OD1 . ASN A 1 650 ? 131.463 123.980 127.614 1.00 97.53  ? 650 ASN A OD1 1 
ATOM   4320  N ND2 . ASN A 1 650 ? 133.187 122.563 127.430 1.00 89.13  ? 650 ASN A ND2 1 
ATOM   4321  N N   . HIS A 1 651 ? 130.671 126.824 126.837 1.00 92.25  ? 651 HIS A N   1 
ATOM   4322  C CA  . HIS A 1 651 ? 129.614 127.127 125.829 1.00 93.13  ? 651 HIS A CA  1 
ATOM   4323  C C   . HIS A 1 651 ? 129.101 125.887 125.091 1.00 93.03  ? 651 HIS A C   1 
ATOM   4324  O O   . HIS A 1 651 ? 128.150 126.049 124.330 1.00 88.40  ? 651 HIS A O   1 
ATOM   4325  C CB  . HIS A 1 651 ? 130.061 128.292 124.939 1.00 91.15  ? 651 HIS A CB  1 
ATOM   4326  C CG  . HIS A 1 651 ? 130.359 129.537 125.703 1.00 91.91  ? 651 HIS A CG  1 
ATOM   4327  N ND1 . HIS A 1 651 ? 129.470 130.084 126.599 1.00 90.52  ? 651 HIS A ND1 1 
ATOM   4328  C CD2 . HIS A 1 651 ? 131.441 130.340 125.711 1.00 92.65  ? 651 HIS A CD2 1 
ATOM   4329  C CE1 . HIS A 1 651 ? 129.997 131.165 127.131 1.00 90.40  ? 651 HIS A CE1 1 
ATOM   4330  N NE2 . HIS A 1 651 ? 131.202 131.345 126.602 1.00 87.23  ? 651 HIS A NE2 1 
ATOM   4331  N N   . VAL A 1 652 ? 129.689 124.705 125.299 1.00 102.31 ? 652 VAL A N   1 
ATOM   4332  C CA  . VAL A 1 652 ? 129.129 123.479 124.716 1.00 98.34  ? 652 VAL A CA  1 
ATOM   4333  C C   . VAL A 1 652 ? 127.628 123.437 125.027 1.00 99.19  ? 652 VAL A C   1 
ATOM   4334  O O   . VAL A 1 652 ? 127.222 123.698 126.158 1.00 98.23  ? 652 VAL A O   1 
ATOM   4335  C CB  . VAL A 1 652 ? 129.861 122.235 125.250 1.00 96.77  ? 652 VAL A CB  1 
ATOM   4336  C CG1 . VAL A 1 652 ? 129.217 120.926 124.780 1.00 97.31  ? 652 VAL A CG1 1 
ATOM   4337  C CG2 . VAL A 1 652 ? 131.315 122.210 124.773 1.00 96.64  ? 652 VAL A CG2 1 
ATOM   4338  N N   . ALA A 1 653 ? 126.790 123.143 124.032 1.00 108.54 ? 653 ALA A N   1 
ATOM   4339  C CA  . ALA A 1 653 ? 125.340 123.089 124.207 1.00 108.60 ? 653 ALA A CA  1 
ATOM   4340  C C   . ALA A 1 653 ? 124.944 121.970 125.183 1.00 107.17 ? 653 ALA A C   1 
ATOM   4341  O O   . ALA A 1 653 ? 125.520 120.884 125.154 1.00 105.39 ? 653 ALA A O   1 
ATOM   4342  C CB  . ALA A 1 653 ? 124.684 122.918 122.835 1.00 106.05 ? 653 ALA A CB  1 
ATOM   4343  N N   . ASP A 1 654 ? 123.976 122.224 126.061 1.00 106.66 ? 654 ASP A N   1 
ATOM   4344  C CA  . ASP A 1 654 ? 123.733 121.367 127.222 1.00 105.79 ? 654 ASP A CA  1 
ATOM   4345  C C   . ASP A 1 654 ? 123.252 119.951 126.834 1.00 106.70 ? 654 ASP A C   1 
ATOM   4346  O O   . ASP A 1 654 ? 122.177 119.777 126.259 1.00 100.92 ? 654 ASP A O   1 
ATOM   4347  C CB  . ASP A 1 654 ? 122.751 122.067 128.173 1.00 106.60 ? 654 ASP A CB  1 
ATOM   4348  C CG  . ASP A 1 654 ? 122.594 121.336 129.512 1.00 109.56 ? 654 ASP A CG  1 
ATOM   4349  O OD1 . ASP A 1 654 ? 123.360 120.388 129.786 1.00 108.24 ? 654 ASP A OD1 1 
ATOM   4350  O OD2 . ASP A 1 654 ? 121.673 121.674 130.285 1.00 107.00 ? 654 ASP A OD2 1 
ATOM   4351  N N   . ASN A 1 655 ? 124.034 118.918 127.191 1.00 104.95 ? 655 ASN A N   1 
ATOM   4352  C CA  . ASN A 1 655 ? 123.696 117.512 126.801 1.00 102.07 ? 655 ASN A CA  1 
ATOM   4353  C C   . ASN A 1 655 ? 123.039 116.757 127.964 1.00 104.20 ? 655 ASN A C   1 
ATOM   4354  O O   . ASN A 1 655 ? 123.170 115.518 127.999 1.00 105.89 ? 655 ASN A O   1 
ATOM   4355  C CB  . ASN A 1 655 ? 124.926 116.759 126.286 1.00 101.08 ? 655 ASN A CB  1 
ATOM   4356  C CG  . ASN A 1 655 ? 125.500 117.359 125.020 1.00 109.41 ? 655 ASN A CG  1 
ATOM   4357  O OD1 . ASN A 1 655 ? 126.577 116.967 124.575 1.00 109.61 ? 655 ASN A OD1 1 
ATOM   4358  N ND2 . ASN A 1 655 ? 124.791 118.309 124.433 1.00 110.97 ? 655 ASN A ND2 1 
ATOM   4359  N N   . SER A 1 656 ? 122.353 117.460 128.864 1.00 95.66  ? 656 SER A N   1 
ATOM   4360  C CA  . SER A 1 656 ? 121.661 116.884 130.015 1.00 89.24  ? 656 SER A CA  1 
ATOM   4361  C C   . SER A 1 656 ? 120.332 116.192 129.718 1.00 90.27  ? 656 SER A C   1 
ATOM   4362  O O   . SER A 1 656 ? 120.076 115.146 130.306 1.00 95.03  ? 656 SER A O   1 
ATOM   4363  C CB  . SER A 1 656 ? 121.444 117.951 131.085 1.00 93.22  ? 656 SER A CB  1 
ATOM   4364  O OG  . SER A 1 656 ? 120.638 118.980 130.563 1.00 98.66  ? 656 SER A OG  1 
ATOM   4365  N N   . TRP A 1 657 ? 119.516 116.677 128.781 1.00 82.07  ? 657 TRP A N   1 
ATOM   4366  C CA  . TRP A 1 657 ? 118.277 115.993 128.376 1.00 85.23  ? 657 TRP A CA  1 
ATOM   4367  C C   . TRP A 1 657 ? 118.535 114.581 127.846 1.00 84.90  ? 657 TRP A C   1 
ATOM   4368  O O   . TRP A 1 657 ? 117.853 113.628 128.204 1.00 89.28  ? 657 TRP A O   1 
ATOM   4369  C CB  . TRP A 1 657 ? 117.539 116.853 127.348 1.00 81.06  ? 657 TRP A CB  1 
ATOM   4370  C CG  . TRP A 1 657 ? 116.376 116.197 126.669 1.00 84.50  ? 657 TRP A CG  1 
ATOM   4371  C CD1 . TRP A 1 657 ? 115.107 116.147 127.132 1.00 85.70  ? 657 TRP A CD1 1 
ATOM   4372  C CD2 . TRP A 1 657 ? 116.355 115.482 125.397 1.00 90.69  ? 657 TRP A CD2 1 
ATOM   4373  N NE1 . TRP A 1 657 ? 114.313 115.444 126.251 1.00 84.29  ? 657 TRP A NE1 1 
ATOM   4374  C CE2 . TRP A 1 657 ? 115.031 115.011 125.161 1.00 90.65  ? 657 TRP A CE2 1 
ATOM   4375  C CE3 . TRP A 1 657 ? 117.317 115.220 124.398 1.00 88.55  ? 657 TRP A CE3 1 
ATOM   4376  C CZ2 . TRP A 1 657 ? 114.686 114.300 124.004 1.00 85.72  ? 657 TRP A CZ2 1 
ATOM   4377  C CZ3 . TRP A 1 657 ? 116.979 114.508 123.236 1.00 85.60  ? 657 TRP A CZ3 1 
ATOM   4378  C CH2 . TRP A 1 657 ? 115.669 114.039 123.038 1.00 82.60  ? 657 TRP A CH2 1 
ATOM   4379  N N   . SER A 1 658 ? 119.585 114.416 127.052 1.00 77.42  ? 658 SER A N   1 
ATOM   4380  C CA  . SER A 1 658 ? 119.972 113.127 126.464 1.00 69.87  ? 658 SER A CA  1 
ATOM   4381  C C   . SER A 1 658 ? 120.651 112.193 127.468 1.00 76.28  ? 658 SER A C   1 
ATOM   4382  O O   . SER A 1 658 ? 120.463 110.983 127.405 1.00 83.36  ? 658 SER A O   1 
ATOM   4383  C CB  . SER A 1 658 ? 120.827 113.347 125.217 1.00 70.74  ? 658 SER A CB  1 
ATOM   4384  O OG  . SER A 1 658 ? 122.119 113.821 125.531 1.00 80.87  ? 658 SER A OG  1 
ATOM   4385  N N   . ILE A 1 659 ? 121.436 112.716 128.405 1.00 69.80  ? 659 ILE A N   1 
ATOM   4386  C CA  . ILE A 1 659 ? 122.006 111.894 129.478 1.00 67.00  ? 659 ILE A CA  1 
ATOM   4387  C C   . ILE A 1 659 ? 120.886 111.444 130.424 1.00 66.86  ? 659 ILE A C   1 
ATOM   4388  O O   . ILE A 1 659 ? 120.875 110.297 130.855 1.00 75.38  ? 659 ILE A O   1 
ATOM   4389  C CB  . ILE A 1 659 ? 123.161 112.638 130.168 1.00 69.70  ? 659 ILE A CB  1 
ATOM   4390  C CG1 . ILE A 1 659 ? 124.348 112.829 129.213 1.00 70.18  ? 659 ILE A CG1 1 
ATOM   4391  C CG2 . ILE A 1 659 ? 123.614 111.895 131.434 1.00 71.87  ? 659 ILE A CG2 1 
ATOM   4392  C CD1 . ILE A 1 659 ? 125.402 113.810 129.719 1.00 69.77  ? 659 ILE A CD1 1 
ATOM   4393  N N   . TRP A 1 660 ? 119.870 112.270 130.665 1.00 57.69  ? 660 TRP A N   1 
ATOM   4394  C CA  . TRP A 1 660 ? 118.658 111.857 131.364 1.00 62.85  ? 660 TRP A CA  1 
ATOM   4395  C C   . TRP A 1 660 ? 117.853 110.798 130.601 1.00 66.83  ? 660 TRP A C   1 
ATOM   4396  O O   . TRP A 1 660 ? 117.448 109.799 131.186 1.00 76.34  ? 660 TRP A O   1 
ATOM   4397  C CB  . TRP A 1 660 ? 117.821 113.089 131.684 1.00 66.34  ? 660 TRP A CB  1 
ATOM   4398  C CG  . TRP A 1 660 ? 116.460 112.778 132.200 1.00 65.92  ? 660 TRP A CG  1 
ATOM   4399  C CD1 . TRP A 1 660 ? 116.189 112.114 133.341 1.00 62.83  ? 660 TRP A CD1 1 
ATOM   4400  C CD2 . TRP A 1 660 ? 115.175 113.023 131.563 1.00 64.71  ? 660 TRP A CD2 1 
ATOM   4401  N NE1 . TRP A 1 660 ? 114.828 111.957 133.467 1.00 55.94  ? 660 TRP A NE1 1 
ATOM   4402  C CE2 . TRP A 1 660 ? 114.154 112.510 132.407 1.00 63.10  ? 660 TRP A CE2 1 
ATOM   4403  C CE3 . TRP A 1 660 ? 114.774 113.618 130.353 1.00 69.52  ? 660 TRP A CE3 1 
ATOM   4404  C CZ2 . TRP A 1 660 ? 112.796 112.610 132.084 1.00 67.17  ? 660 TRP A CZ2 1 
ATOM   4405  C CZ3 . TRP A 1 660 ? 113.418 113.709 130.009 1.00 70.23  ? 660 TRP A CZ3 1 
ATOM   4406  C CH2 . TRP A 1 660 ? 112.430 113.214 130.873 1.00 68.36  ? 660 TRP A CH2 1 
ATOM   4407  N N   . LYS A 1 661 ? 117.682 110.917 129.283 1.00 67.28  ? 661 LYS A N   1 
ATOM   4408  C CA  . LYS A 1 661 ? 117.082 109.862 128.449 1.00 60.71  ? 661 LYS A CA  1 
ATOM   4409  C C   . LYS A 1 661 ? 117.838 108.537 128.539 1.00 62.82  ? 661 LYS A C   1 
ATOM   4410  O O   . LYS A 1 661 ? 117.204 107.492 128.583 1.00 65.99  ? 661 LYS A O   1 
ATOM   4411  C CB  . LYS A 1 661 ? 117.010 110.338 126.995 1.00 58.01  ? 661 LYS A CB  1 
ATOM   4412  C CG  . LYS A 1 661 ? 115.872 111.333 126.739 1.00 62.18  ? 661 LYS A CG  1 
ATOM   4413  C CD  . LYS A 1 661 ? 114.572 110.603 126.397 1.00 70.03  ? 661 LYS A CD  1 
ATOM   4414  C CE  . LYS A 1 661 ? 113.475 111.607 126.048 1.00 74.58  ? 661 LYS A CE  1 
ATOM   4415  N NZ  . LYS A 1 661 ? 112.334 110.954 125.358 1.00 67.90  ? 661 LYS A NZ  1 
ATOM   4416  N N   . LEU A 1 662 ? 119.167 108.538 128.641 1.00 58.00  ? 662 LEU A N   1 
ATOM   4417  C CA  . LEU A 1 662 ? 119.954 107.328 128.895 1.00 52.44  ? 662 LEU A CA  1 
ATOM   4418  C C   . LEU A 1 662 ? 119.744 106.771 130.306 1.00 68.79  ? 662 LEU A C   1 
ATOM   4419  O O   . LEU A 1 662 ? 119.612 105.563 130.465 1.00 78.01  ? 662 LEU A O   1 
ATOM   4420  C CB  . LEU A 1 662 ? 121.430 107.627 128.593 1.00 52.82  ? 662 LEU A CB  1 
ATOM   4421  C CG  . LEU A 1 662 ? 122.394 106.454 128.829 1.00 58.93  ? 662 LEU A CG  1 
ATOM   4422  C CD1 . LEU A 1 662 ? 122.187 105.301 127.857 1.00 62.25  ? 662 LEU A CD1 1 
ATOM   4423  C CD2 . LEU A 1 662 ? 123.820 106.949 128.671 1.00 62.21  ? 662 LEU A CD2 1 
ATOM   4424  N N   . GLN A 1 663 ? 119.642 107.610 131.335 1.00 62.30  ? 663 GLN A N   1 
ATOM   4425  C CA  . GLN A 1 663 ? 119.298 107.167 132.686 1.00 44.14  ? 663 GLN A CA  1 
ATOM   4426  C C   . GLN A 1 663 ? 117.930 106.482 132.726 1.00 59.13  ? 663 GLN A C   1 
ATOM   4427  O O   . GLN A 1 663 ? 117.795 105.414 133.319 1.00 62.72  ? 663 GLN A O   1 
ATOM   4428  C CB  . GLN A 1 663 ? 119.328 108.356 133.646 1.00 49.05  ? 663 GLN A CB  1 
ATOM   4429  C CG  . GLN A 1 663 ? 120.759 108.802 133.947 1.00 57.74  ? 663 GLN A CG  1 
ATOM   4430  C CD  . GLN A 1 663 ? 120.819 110.020 134.848 1.00 63.94  ? 663 GLN A CD  1 
ATOM   4431  O OE1 . GLN A 1 663 ? 119.831 110.671 135.147 1.00 58.64  ? 663 GLN A OE1 1 
ATOM   4432  N NE2 . GLN A 1 663 ? 121.988 110.364 135.331 1.00 64.63  ? 663 GLN A NE2 1 
ATOM   4433  N N   . LYS A 1 664 ? 116.925 107.038 132.037 1.00 68.27  ? 664 LYS A N   1 
ATOM   4434  C CA  . LYS A 1 664 ? 115.618 106.393 131.862 1.00 55.97  ? 664 LYS A CA  1 
ATOM   4435  C C   . LYS A 1 664 ? 115.678 105.108 131.038 1.00 61.79  ? 664 LYS A C   1 
ATOM   4436  O O   . LYS A 1 664 ? 115.000 104.157 131.394 1.00 72.47  ? 664 LYS A O   1 
ATOM   4437  C CB  . LYS A 1 664 ? 114.611 107.369 131.260 1.00 53.05  ? 664 LYS A CB  1 
ATOM   4438  C CG  . LYS A 1 664 ? 114.324 108.538 132.204 1.00 56.41  ? 664 LYS A CG  1 
ATOM   4439  C CD  . LYS A 1 664 ? 112.913 109.087 132.008 1.00 61.18  ? 664 LYS A CD  1 
ATOM   4440  C CE  . LYS A 1 664 ? 112.678 109.597 130.584 1.00 64.10  ? 664 LYS A CE  1 
ATOM   4441  N NZ  . LYS A 1 664 ? 111.265 110.013 130.394 1.00 69.07  ? 664 LYS A NZ  1 
ATOM   4442  N N   . ALA A 1 665 ? 116.517 105.021 130.007 1.00 48.59  ? 665 ALA A N   1 
ATOM   4443  C CA  . ALA A 1 665 ? 116.755 103.784 129.267 1.00 45.38  ? 665 ALA A CA  1 
ATOM   4444  C C   . ALA A 1 665 ? 117.345 102.673 130.141 1.00 57.27  ? 665 ALA A C   1 
ATOM   4445  O O   . ALA A 1 665 ? 116.821 101.569 130.159 1.00 68.67  ? 665 ALA A O   1 
ATOM   4446  C CB  . ALA A 1 665 ? 117.664 104.075 128.076 1.00 55.42  ? 665 ALA A CB  1 
ATOM   4447  N N   . ILE A 1 666 ? 118.388 102.952 130.920 1.00 66.86  ? 666 ILE A N   1 
ATOM   4448  C CA  . ILE A 1 666 ? 118.996 101.986 131.849 1.00 59.79  ? 666 ILE A CA  1 
ATOM   4449  C C   . ILE A 1 666 ? 117.976 101.514 132.895 1.00 58.29  ? 666 ILE A C   1 
ATOM   4450  O O   . ILE A 1 666 ? 117.878 100.325 133.183 1.00 65.58  ? 666 ILE A O   1 
ATOM   4451  C CB  . ILE A 1 666 ? 120.241 102.620 132.502 1.00 58.52  ? 666 ILE A CB  1 
ATOM   4452  C CG1 . ILE A 1 666 ? 121.362 102.822 131.467 1.00 52.13  ? 666 ILE A CG1 1 
ATOM   4453  C CG2 . ILE A 1 666 ? 120.769 101.767 133.660 1.00 66.01  ? 666 ILE A CG2 1 
ATOM   4454  C CD1 . ILE A 1 666 ? 122.394 103.862 131.892 1.00 58.65  ? 666 ILE A CD1 1 
ATOM   4455  N N   . SER A 1 667 ? 117.173 102.438 133.426 1.00 58.63  ? 667 SER A N   1 
ATOM   4456  C CA  . SER A 1 667 ? 116.089 102.157 134.371 1.00 57.19  ? 667 SER A CA  1 
ATOM   4457  C C   . SER A 1 667 ? 115.026 101.230 133.782 1.00 55.40  ? 667 SER A C   1 
ATOM   4458  O O   . SER A 1 667 ? 114.698 100.209 134.379 1.00 58.75  ? 667 SER A O   1 
ATOM   4459  C CB  . SER A 1 667 ? 115.477 103.486 134.805 1.00 61.39  ? 667 SER A CB  1 
ATOM   4460  O OG  . SER A 1 667 ? 114.388 103.277 135.663 1.00 63.85  ? 667 SER A OG  1 
ATOM   4461  N N   . VAL A 1 668 ? 114.538 101.517 132.572 1.00 65.67  ? 668 VAL A N   1 
ATOM   4462  C CA  . VAL A 1 668 ? 113.587 100.680 131.825 1.00 65.53  ? 668 VAL A CA  1 
ATOM   4463  C C   . VAL A 1 668 ? 114.110 99.269  131.615 1.00 70.24  ? 668 VAL A C   1 
ATOM   4464  O O   . VAL A 1 668 ? 113.419 98.309  131.937 1.00 78.72  ? 668 VAL A O   1 
ATOM   4465  C CB  . VAL A 1 668 ? 113.274 101.343 130.474 1.00 59.88  ? 668 VAL A CB  1 
ATOM   4466  C CG1 . VAL A 1 668 ? 112.723 100.410 129.402 1.00 67.15  ? 668 VAL A CG1 1 
ATOM   4467  C CG2 . VAL A 1 668 ? 112.244 102.440 130.686 1.00 62.97  ? 668 VAL A CG2 1 
ATOM   4468  N N   . LEU A 1 669 ? 115.322 99.129  131.089 1.00 63.77  ? 669 LEU A N   1 
ATOM   4469  C CA  . LEU A 1 669 ? 115.865 97.829  130.715 1.00 60.14  ? 669 LEU A CA  1 
ATOM   4470  C C   . LEU A 1 669 ? 116.137 96.941  131.929 1.00 65.98  ? 669 LEU A C   1 
ATOM   4471  O O   . LEU A 1 669 ? 116.134 95.722  131.800 1.00 75.49  ? 669 LEU A O   1 
ATOM   4472  C CB  . LEU A 1 669 ? 117.128 98.057  129.880 1.00 65.80  ? 669 LEU A CB  1 
ATOM   4473  C CG  . LEU A 1 669 ? 116.858 98.784  128.555 1.00 66.00  ? 669 LEU A CG  1 
ATOM   4474  C CD1 . LEU A 1 669 ? 118.161 99.334  128.004 1.00 66.40  ? 669 LEU A CD1 1 
ATOM   4475  C CD2 . LEU A 1 669 ? 116.238 97.853  127.529 1.00 63.71  ? 669 LEU A CD2 1 
ATOM   4476  N N   . GLU A 1 670 ? 116.326 97.521  133.110 1.00 79.19  ? 670 GLU A N   1 
ATOM   4477  C CA  . GLU A 1 670 ? 116.311 96.808  134.384 1.00 77.84  ? 670 GLU A CA  1 
ATOM   4478  C C   . GLU A 1 670 ? 114.900 96.437  134.859 1.00 77.81  ? 670 GLU A C   1 
ATOM   4479  O O   . GLU A 1 670 ? 114.659 95.272  135.175 1.00 77.90  ? 670 GLU A O   1 
ATOM   4480  C CB  . GLU A 1 670 ? 117.037 97.651  135.438 1.00 73.17  ? 670 GLU A CB  1 
ATOM   4481  C CG  . GLU A 1 670 ? 118.552 97.480  135.329 1.00 79.06  ? 670 GLU A CG  1 
ATOM   4482  C CD  . GLU A 1 670 ? 118.954 96.022  135.575 1.00 89.64  ? 670 GLU A CD  1 
ATOM   4483  O OE1 . GLU A 1 670 ? 118.512 95.445  136.591 1.00 89.29  ? 670 GLU A OE1 1 
ATOM   4484  O OE2 . GLU A 1 670 ? 119.665 95.415  134.739 1.00 93.46  ? 670 GLU A OE2 1 
ATOM   4485  N N   . MET A 1 671 ? 113.951 97.374  134.854 1.00 70.39  ? 671 MET A N   1 
ATOM   4486  C CA  . MET A 1 671 ? 112.564 97.116  135.252 1.00 69.45  ? 671 MET A CA  1 
ATOM   4487  C C   . MET A 1 671 ? 111.851 96.058  134.413 1.00 67.77  ? 671 MET A C   1 
ATOM   4488  O O   . MET A 1 671 ? 111.016 95.328  134.939 1.00 79.28  ? 671 MET A O   1 
ATOM   4489  C CB  . MET A 1 671 ? 111.748 98.403  135.163 1.00 67.53  ? 671 MET A CB  1 
ATOM   4490  C CG  . MET A 1 671 ? 112.051 99.366  136.300 1.00 64.09  ? 671 MET A CG  1 
ATOM   4491  S SD  . MET A 1 671 ? 110.857 100.703 136.397 1.00 67.34  ? 671 MET A SD  1 
ATOM   4492  C CE  . MET A 1 671 ? 111.246 101.649 134.914 1.00 70.66  ? 671 MET A CE  1 
ATOM   4493  N N   . GLU A 1 672 ? 112.161 95.925  133.127 1.00 73.88  ? 672 GLU A N   1 
ATOM   4494  C CA  . GLU A 1 672 ? 111.560 94.906  132.260 1.00 76.45  ? 672 GLU A CA  1 
ATOM   4495  C C   . GLU A 1 672 ? 111.823 93.459  132.702 1.00 80.94  ? 672 GLU A C   1 
ATOM   4496  O O   . GLU A 1 672 ? 111.064 92.572  132.329 1.00 77.09  ? 672 GLU A O   1 
ATOM   4497  C CB  . GLU A 1 672 ? 112.084 95.079  130.834 1.00 75.01  ? 672 GLU A CB  1 
ATOM   4498  C CG  . GLU A 1 672 ? 111.360 96.188  130.070 1.00 77.20  ? 672 GLU A CG  1 
ATOM   4499  C CD  . GLU A 1 672 ? 111.768 96.147  128.597 1.00 85.84  ? 672 GLU A CD  1 
ATOM   4500  O OE1 . GLU A 1 672 ? 112.966 95.962  128.307 1.00 85.17  ? 672 GLU A OE1 1 
ATOM   4501  O OE2 . GLU A 1 672 ? 110.898 96.253  127.708 1.00 85.99  ? 672 GLU A OE2 1 
ATOM   4502  N N   . ASN A 1 673 ? 112.862 93.197  133.501 1.00 88.96  ? 673 ASN A N   1 
ATOM   4503  C CA  . ASN A 1 673 ? 113.135 91.866  134.056 1.00 86.04  ? 673 ASN A CA  1 
ATOM   4504  C C   . ASN A 1 673 ? 112.296 91.556  135.302 1.00 85.70  ? 673 ASN A C   1 
ATOM   4505  O O   . ASN A 1 673 ? 112.337 90.439  135.805 1.00 91.09  ? 673 ASN A O   1 
ATOM   4506  C CB  . ASN A 1 673 ? 114.628 91.718  134.378 1.00 88.08  ? 673 ASN A CB  1 
ATOM   4507  C CG  . ASN A 1 673 ? 115.516 92.195  133.257 1.00 86.53  ? 673 ASN A CG  1 
ATOM   4508  O OD1 . ASN A 1 673 ? 115.712 91.536  132.248 1.00 85.00  ? 673 ASN A OD1 1 
ATOM   4509  N ND2 . ASN A 1 673 ? 116.032 93.387  133.394 1.00 83.18  ? 673 ASN A ND2 1 
ATOM   4510  N N   . GLY A 1 674 ? 111.547 92.520  135.832 1.00 84.65  ? 674 GLY A N   1 
ATOM   4511  C CA  . GLY A 1 674 ? 110.876 92.390  137.117 1.00 83.46  ? 674 GLY A CA  1 
ATOM   4512  C C   . GLY A 1 674 ? 111.877 92.441  138.266 1.00 86.28  ? 674 GLY A C   1 
ATOM   4513  O O   . GLY A 1 674 ? 112.750 93.303  138.305 1.00 90.01  ? 674 GLY A O   1 
ATOM   4514  N N   . TYR A 1 675 ? 111.747 91.513  139.204 1.00 87.36  ? 675 TYR A N   1 
ATOM   4515  C CA  . TYR A 1 675 ? 112.548 91.443  140.424 1.00 88.28  ? 675 TYR A CA  1 
ATOM   4516  C C   . TYR A 1 675 ? 113.266 90.096  140.529 1.00 89.58  ? 675 TYR A C   1 
ATOM   4517  O O   . TYR A 1 675 ? 112.826 89.112  139.943 1.00 92.01  ? 675 TYR A O   1 
ATOM   4518  C CB  . TYR A 1 675 ? 111.645 91.659  141.640 1.00 86.22  ? 675 TYR A CB  1 
ATOM   4519  C CG  . TYR A 1 675 ? 110.767 92.899  141.638 1.00 88.03  ? 675 TYR A CG  1 
ATOM   4520  C CD1 . TYR A 1 675 ? 111.341 94.181  141.740 1.00 83.48  ? 675 TYR A CD1 1 
ATOM   4521  C CD2 . TYR A 1 675 ? 109.370 92.762  141.600 1.00 87.74  ? 675 TYR A CD2 1 
ATOM   4522  C CE1 . TYR A 1 675 ? 110.519 95.321  141.799 1.00 84.75  ? 675 TYR A CE1 1 
ATOM   4523  C CE2 . TYR A 1 675 ? 108.546 93.897  141.661 1.00 84.83  ? 675 TYR A CE2 1 
ATOM   4524  C CZ  . TYR A 1 675 ? 109.117 95.179  141.759 1.00 86.33  ? 675 TYR A CZ  1 
ATOM   4525  O OH  . TYR A 1 675 ? 108.301 96.261  141.817 1.00 86.61  ? 675 TYR A OH  1 
ATOM   4526  N N   . TRP A 1 676 ? 114.334 90.013  141.321 1.00 87.26  ? 676 TRP A N   1 
ATOM   4527  C CA  . TRP A 1 676 ? 115.142 88.793  141.479 1.00 84.73  ? 676 TRP A CA  1 
ATOM   4528  C C   . TRP A 1 676 ? 114.322 87.545  141.866 1.00 87.96  ? 676 TRP A C   1 
ATOM   4529  O O   . TRP A 1 676 ? 114.675 86.432  141.474 1.00 92.78  ? 676 TRP A O   1 
ATOM   4530  C CB  . TRP A 1 676 ? 116.241 89.080  142.512 1.00 84.47  ? 676 TRP A CB  1 
ATOM   4531  C CG  . TRP A 1 676 ? 115.783 89.345  143.916 1.00 90.74  ? 676 TRP A CG  1 
ATOM   4532  C CD1 . TRP A 1 676 ? 115.520 90.559  144.451 1.00 87.43  ? 676 TRP A CD1 1 
ATOM   4533  C CD2 . TRP A 1 676 ? 115.501 88.381  144.975 1.00 88.67  ? 676 TRP A CD2 1 
ATOM   4534  N NE1 . TRP A 1 676 ? 115.089 90.408  145.751 1.00 85.19  ? 676 TRP A NE1 1 
ATOM   4535  C CE2 . TRP A 1 676 ? 115.039 89.086  146.119 1.00 86.51  ? 676 TRP A CE2 1 
ATOM   4536  C CE3 . TRP A 1 676 ? 115.582 86.975  145.080 1.00 84.71  ? 676 TRP A CE3 1 
ATOM   4537  C CZ2 . TRP A 1 676 ? 114.651 88.435  147.296 1.00 85.81  ? 676 TRP A CZ2 1 
ATOM   4538  C CZ3 . TRP A 1 676 ? 115.196 86.311  146.257 1.00 87.19  ? 676 TRP A CZ3 1 
ATOM   4539  C CH2 . TRP A 1 676 ? 114.723 87.036  147.360 1.00 87.66  ? 676 TRP A CH2 1 
ATOM   4540  N N   . TRP A 1 677 ? 113.212 87.735  142.586 1.00 88.94  ? 677 TRP A N   1 
ATOM   4541  C CA  . TRP A 1 677 ? 112.254 86.723  143.050 1.00 90.93  ? 677 TRP A CA  1 
ATOM   4542  C C   . TRP A 1 677 ? 111.044 86.505  142.121 1.00 94.40  ? 677 TRP A C   1 
ATOM   4543  O O   . TRP A 1 677 ? 110.307 85.534  142.296 1.00 96.28  ? 677 TRP A O   1 
ATOM   4544  C CB  . TRP A 1 677 ? 111.764 87.171  144.434 1.00 88.68  ? 677 TRP A CB  1 
ATOM   4545  C CG  . TRP A 1 677 ? 111.034 88.482  144.467 1.00 85.07  ? 677 TRP A CG  1 
ATOM   4546  C CD1 . TRP A 1 677 ? 111.616 89.696  144.564 1.00 88.46  ? 677 TRP A CD1 1 
ATOM   4547  C CD2 . TRP A 1 677 ? 109.599 88.748  144.399 1.00 87.41  ? 677 TRP A CD2 1 
ATOM   4548  N NE1 . TRP A 1 677 ? 110.657 90.682  144.528 1.00 89.12  ? 677 TRP A NE1 1 
ATOM   4549  C CE2 . TRP A 1 677 ? 109.396 90.160  144.402 1.00 89.10  ? 677 TRP A CE2 1 
ATOM   4550  C CE3 . TRP A 1 677 ? 108.445 87.942  144.345 1.00 89.28  ? 677 TRP A CE3 1 
ATOM   4551  C CZ2 . TRP A 1 677 ? 108.128 90.745  144.304 1.00 88.06  ? 677 TRP A CZ2 1 
ATOM   4552  C CZ3 . TRP A 1 677 ? 107.162 88.517  144.249 1.00 92.34  ? 677 TRP A CZ3 1 
ATOM   4553  C CH2 . TRP A 1 677 ? 107.005 89.911  144.214 1.00 90.62  ? 677 TRP A CH2 1 
ATOM   4554  N N   . CYS A 1 678 ? 110.806 87.389  141.151 1.00 96.73  ? 678 CYS A N   1 
ATOM   4555  C CA  . CYS A 1 678 ? 109.633 87.397  140.269 1.00 96.26  ? 678 CYS A CA  1 
ATOM   4556  C C   . CYS A 1 678 ? 110.034 87.969  138.906 1.00 98.92  ? 678 CYS A C   1 
ATOM   4557  O O   . CYS A 1 678 ? 109.893 89.163  138.625 1.00 100.42 ? 678 CYS A O   1 
ATOM   4558  C CB  . CYS A 1 678 ? 108.491 88.175  140.931 1.00 99.90  ? 678 CYS A CB  1 
ATOM   4559  S SG  . CYS A 1 678 ? 107.031 88.240  139.851 1.00 101.59 ? 678 CYS A SG  1 
ATOM   4560  N N   . ARG A 1 679 ? 110.635 87.098  138.093 1.00 102.44 ? 679 ARG A N   1 
ATOM   4561  C CA  . ARG A 1 679 ? 111.291 87.446  136.828 1.00 99.87  ? 679 ARG A CA  1 
ATOM   4562  C C   . ARG A 1 679 ? 110.236 87.554  135.729 1.00 99.70  ? 679 ARG A C   1 
ATOM   4563  O O   . ARG A 1 679 ? 109.681 86.552  135.291 1.00 100.11 ? 679 ARG A O   1 
ATOM   4564  C CB  . ARG A 1 679 ? 112.418 86.437  136.536 1.00 98.28  ? 679 ARG A CB  1 
ATOM   4565  C CG  . ARG A 1 679 ? 113.476 86.489  137.657 1.00 99.48  ? 679 ARG A CG  1 
ATOM   4566  C CD  . ARG A 1 679 ? 114.554 85.410  137.551 1.00 101.77 ? 679 ARG A CD  1 
ATOM   4567  N NE  . ARG A 1 679 ? 115.272 85.282  138.835 1.00 106.47 ? 679 ARG A NE  1 
ATOM   4568  C CZ  . ARG A 1 679 ? 116.304 84.516  139.123 1.00 104.43 ? 679 ARG A CZ  1 
ATOM   4569  N NH1 . ARG A 1 679 ? 116.761 84.497  140.336 1.00 100.65 ? 679 ARG A NH1 1 
ATOM   4570  N NH2 . ARG A 1 679 ? 116.886 83.765  138.237 1.00 100.91 ? 679 ARG A NH2 1 
ATOM   4571  N N   . ARG A 1 680 ? 109.919 88.787  135.339 1.00 100.63 ? 680 ARG A N   1 
ATOM   4572  C CA  . ARG A 1 680 ? 108.799 89.185  134.469 1.00 96.87  ? 680 ARG A CA  1 
ATOM   4573  C C   . ARG A 1 680 ? 108.925 88.615  133.053 1.00 101.71 ? 680 ARG A C   1 
ATOM   4574  O O   . ARG A 1 680 ? 109.995 88.656  132.458 1.00 100.59 ? 680 ARG A O   1 
ATOM   4575  C CB  . ARG A 1 680 ? 108.760 90.724  134.488 1.00 98.04  ? 680 ARG A CB  1 
ATOM   4576  C CG  . ARG A 1 680 ? 107.817 91.420  133.507 1.00 98.38  ? 680 ARG A CG  1 
ATOM   4577  C CD  . ARG A 1 680 ? 107.869 92.937  133.752 1.00 102.05 ? 680 ARG A CD  1 
ATOM   4578  N NE  . ARG A 1 680 ? 107.419 93.707  132.574 1.00 102.50 ? 680 ARG A NE  1 
ATOM   4579  C CZ  . ARG A 1 680 ? 106.406 94.547  132.491 1.00 105.34 ? 680 ARG A CZ  1 
ATOM   4580  N NH1 . ARG A 1 680 ? 106.178 95.195  131.387 1.00 101.87 ? 680 ARG A NH1 1 
ATOM   4581  N NH2 . ARG A 1 680 ? 105.591 94.758  133.481 1.00 103.84 ? 680 ARG A NH2 1 
ATOM   4582  N N   . LYS A 1 681 ? 107.821 88.133  132.490 1.00 111.64 ? 681 LYS A N   1 
ATOM   4583  C CA  . LYS A 1 681 ? 107.735 87.747  131.080 1.00 109.83 ? 681 LYS A CA  1 
ATOM   4584  C C   . LYS A 1 681 ? 107.678 88.990  130.188 1.00 110.00 ? 681 LYS A C   1 
ATOM   4585  O O   . LYS A 1 681 ? 106.768 89.809  130.328 1.00 108.52 ? 681 LYS A O   1 
ATOM   4586  C CB  . LYS A 1 681 ? 106.491 86.888  130.877 1.00 104.08 ? 681 LYS A CB  1 
ATOM   4587  N N   . LYS A 1 682 ? 108.650 89.162  129.284 1.00 95.89  ? 682 LYS A N   1 
ATOM   4588  C CA  . LYS A 1 682 ? 108.774 90.370  128.452 1.00 97.99  ? 682 LYS A CA  1 
ATOM   4589  C C   . LYS A 1 682 ? 107.714 90.440  127.349 1.00 102.44 ? 682 LYS A C   1 
ATOM   4590  O O   . LYS A 1 682 ? 107.591 89.537  126.525 1.00 98.18  ? 682 LYS A O   1 
ATOM   4591  C CB  . LYS A 1 682 ? 110.186 90.475  127.855 1.00 97.43  ? 682 LYS A CB  1 
ATOM   4592  C CG  . LYS A 1 682 ? 111.240 90.812  128.918 1.00 99.21  ? 682 LYS A CG  1 
ATOM   4593  C CD  . LYS A 1 682 ? 112.611 90.956  128.258 1.00 99.55  ? 682 LYS A CD  1 
ATOM   4594  C CE  . LYS A 1 682 ? 113.685 91.336  129.274 1.00 97.65  ? 682 LYS A CE  1 
ATOM   4595  N NZ  . LYS A 1 682 ? 115.028 91.351  128.641 1.00 98.54  ? 682 LYS A NZ  1 
ATOM   4596  N N   . HIS A 1 683 ? 106.990 91.556  127.310 1.00 103.16 ? 683 HIS A N   1 
ATOM   4597  C CA  . HIS A 1 683 ? 106.121 91.975  126.204 1.00 99.60  ? 683 HIS A CA  1 
ATOM   4598  C C   . HIS A 1 683 ? 106.960 92.414  124.992 1.00 98.73  ? 683 HIS A C   1 
ATOM   4599  O O   . HIS A 1 683 ? 108.052 92.956  125.161 1.00 99.98  ? 683 HIS A O   1 
ATOM   4600  C CB  . HIS A 1 683 ? 105.202 93.090  126.735 1.00 99.52  ? 683 HIS A CB  1 
ATOM   4601  C CG  . HIS A 1 683 ? 104.394 93.811  125.690 1.00 106.44 ? 683 HIS A CG  1 
ATOM   4602  N ND1 . HIS A 1 683 ? 104.710 95.058  125.155 1.00 102.00 ? 683 HIS A ND1 1 
ATOM   4603  C CD2 . HIS A 1 683 ? 103.249 93.361  125.111 1.00 104.29 ? 683 HIS A CD2 1 
ATOM   4604  C CE1 . HIS A 1 683 ? 103.748 95.337  124.265 1.00 100.82 ? 683 HIS A CE1 1 
ATOM   4605  N NE2 . HIS A 1 683 ? 102.856 94.334  124.220 1.00 101.58 ? 683 HIS A NE2 1 
ATOM   4606  N N   . ARG A 1 684 ? 106.473 92.159  123.771 1.00 88.21  ? 684 ARG A N   1 
ATOM   4607  C CA  . ARG A 1 684 ? 107.165 92.449  122.505 1.00 86.65  ? 684 ARG A CA  1 
ATOM   4608  C C   . ARG A 1 684 ? 106.585 93.694  121.842 1.00 88.38  ? 684 ARG A C   1 
ATOM   4609  O O   . ARG A 1 684 ? 105.372 93.793  121.670 1.00 88.88  ? 684 ARG A O   1 
ATOM   4610  C CB  . ARG A 1 684 ? 107.071 91.218  121.596 1.00 86.07  ? 684 ARG A CB  1 
ATOM   4611  C CG  . ARG A 1 684 ? 108.033 91.302  120.412 1.00 81.98  ? 684 ARG A CG  1 
ATOM   4612  C CD  . ARG A 1 684 ? 108.020 89.992  119.628 1.00 81.18  ? 684 ARG A CD  1 
ATOM   4613  N NE  . ARG A 1 684 ? 109.099 89.960  118.631 1.00 88.79  ? 684 ARG A NE  1 
ATOM   4614  C CZ  . ARG A 1 684 ? 109.430 88.946  117.859 1.00 91.31  ? 684 ARG A CZ  1 
ATOM   4615  N NH1 . ARG A 1 684 ? 110.448 89.033  117.058 1.00 87.79  ? 684 ARG A NH1 1 
ATOM   4616  N NH2 . ARG A 1 684 ? 108.764 87.829  117.864 1.00 90.97  ? 684 ARG A NH2 1 
ATOM   4617  N N   . GLU A 1 685 ? 107.428 94.658  121.505 1.00 88.14  ? 685 GLU A N   1 
ATOM   4618  C CA  . GLU A 1 685 ? 107.006 95.966  120.994 1.00 88.68  ? 685 GLU A CA  1 
ATOM   4619  C C   . GLU A 1 685 ? 106.707 95.939  119.485 1.00 89.96  ? 685 GLU A C   1 
ATOM   4620  O O   . GLU A 1 685 ? 107.244 95.124  118.738 1.00 93.14  ? 685 GLU A O   1 
ATOM   4621  C CB  . GLU A 1 685 ? 108.069 97.031  121.288 1.00 88.72  ? 685 GLU A CB  1 
ATOM   4622  C CG  . GLU A 1 685 ? 108.602 97.061  122.728 1.00 89.74  ? 685 GLU A CG  1 
ATOM   4623  C CD  . GLU A 1 685 ? 107.627 97.539  123.805 1.00 91.04  ? 685 GLU A CD  1 
ATOM   4624  O OE1 . GLU A 1 685 ? 106.555 98.086  123.481 1.00 94.70  ? 685 GLU A OE1 1 
ATOM   4625  O OE2 . GLU A 1 685 ? 107.993 97.397  124.990 1.00 93.44  ? 685 GLU A OE2 1 
ATOM   4626  N N   . GLY A 1 686 ? 105.876 96.862  119.008 1.00 80.42  ? 686 GLY A N   1 
ATOM   4627  C CA  . GLY A 1 686 ? 105.463 96.906  117.607 1.00 80.34  ? 686 GLY A CA  1 
ATOM   4628  C C   . GLY A 1 686 ? 104.453 95.821  117.226 1.00 82.16  ? 686 GLY A C   1 
ATOM   4629  O O   . GLY A 1 686 ? 103.865 95.163  118.082 1.00 81.79  ? 686 GLY A O   1 
ATOM   4630  N N   . ARG A 1 687 ? 104.222 95.656  115.924 1.00 93.46  ? 687 ARG A N   1 
ATOM   4631  C CA  . ARG A 1 687 ? 103.278 94.707  115.318 1.00 91.04  ? 687 ARG A CA  1 
ATOM   4632  C C   . ARG A 1 687 ? 103.966 93.912  114.222 1.00 89.37  ? 687 ARG A C   1 
ATOM   4633  O O   . ARG A 1 687 ? 104.786 94.462  113.497 1.00 91.72  ? 687 ARG A O   1 
ATOM   4634  C CB  . ARG A 1 687 ? 102.080 95.451  114.710 1.00 93.14  ? 687 ARG A CB  1 
ATOM   4635  C CG  . ARG A 1 687 ? 101.234 96.220  115.723 1.00 96.82  ? 687 ARG A CG  1 
ATOM   4636  C CD  . ARG A 1 687 ? 100.008 96.820  115.036 1.00 95.84  ? 687 ARG A CD  1 
ATOM   4637  N NE  . ARG A 1 687 ? 99.206  97.636  115.961 1.00 101.36 ? 687 ARG A NE  1 
ATOM   4638  C CZ  . ARG A 1 687 ? 97.968  98.054  115.776 1.00 100.53 ? 687 ARG A CZ  1 
ATOM   4639  N NH1 . ARG A 1 687 ? 97.369  98.768  116.680 1.00 93.59  ? 687 ARG A NH1 1 
ATOM   4640  N NH2 . ARG A 1 687 ? 97.303  97.782  114.696 1.00 97.20  ? 687 ARG A NH2 1 
ATOM   4641  N N   . LEU A 1 688 ? 103.596 92.652  114.041 1.00 84.03  ? 688 LEU A N   1 
ATOM   4642  C CA  . LEU A 1 688 ? 104.022 91.869  112.882 1.00 88.31  ? 688 LEU A CA  1 
ATOM   4643  C C   . LEU A 1 688 ? 103.288 92.352  111.623 1.00 90.97  ? 688 LEU A C   1 
ATOM   4644  O O   . LEU A 1 688 ? 102.096 92.099  111.473 1.00 95.43  ? 688 LEU A O   1 
ATOM   4645  C CB  . LEU A 1 688 ? 103.787 90.380  113.175 1.00 92.33  ? 688 LEU A CB  1 
ATOM   4646  C CG  . LEU A 1 688 ? 104.196 89.425  112.045 1.00 93.29  ? 688 LEU A CG  1 
ATOM   4647  C CD1 . LEU A 1 688 ? 105.662 89.562  111.670 1.00 93.90  ? 688 LEU A CD1 1 
ATOM   4648  C CD2 . LEU A 1 688 ? 103.961 87.988  112.484 1.00 93.30  ? 688 LEU A CD2 1 
ATOM   4649  N N   . LEU A 1 689 ? 103.985 93.042  110.724 1.00 96.65  ? 689 LEU A N   1 
ATOM   4650  C CA  . LEU A 1 689 ? 103.418 93.647  109.518 1.00 97.36  ? 689 LEU A CA  1 
ATOM   4651  C C   . LEU A 1 689 ? 104.164 93.193  108.265 1.00 98.52  ? 689 LEU A C   1 
ATOM   4652  O O   . LEU A 1 689 ? 105.391 93.104  108.262 1.00 102.84 ? 689 LEU A O   1 
ATOM   4653  C CB  . LEU A 1 689 ? 103.454 95.182  109.635 1.00 96.65  ? 689 LEU A CB  1 
ATOM   4654  C CG  . LEU A 1 689 ? 102.597 95.776  110.763 1.00 100.75 ? 689 LEU A CG  1 
ATOM   4655  C CD1 . LEU A 1 689 ? 102.798 97.281  110.833 1.00 95.11  ? 689 LEU A CD1 1 
ATOM   4656  C CD2 . LEU A 1 689 ? 101.108 95.524  110.558 1.00 99.22  ? 689 LEU A CD2 1 
ATOM   4657  N N   . LYS A 1 690 ? 103.426 92.946  107.178 1.00 107.96 ? 690 LYS A N   1 
ATOM   4658  C CA  . LYS A 1 690 ? 103.990 92.754  105.834 1.00 111.69 ? 690 LYS A CA  1 
ATOM   4659  C C   . LYS A 1 690 ? 104.466 94.097  105.280 1.00 109.89 ? 690 LYS A C   1 
ATOM   4660  O O   . LYS A 1 690 ? 103.653 94.986  105.036 1.00 107.45 ? 690 LYS A O   1 
ATOM   4661  C CB  . LYS A 1 690 ? 102.942 92.096  104.920 1.00 109.95 ? 690 LYS A CB  1 
ATOM   4662  C CG  . LYS A 1 690 ? 103.486 91.836  103.509 1.00 109.58 ? 690 LYS A CG  1 
ATOM   4663  C CD  . LYS A 1 690 ? 102.450 91.117  102.643 1.00 108.92 ? 690 LYS A CD  1 
ATOM   4664  C CE  . LYS A 1 690 ? 102.909 91.077  101.188 1.00 109.69 ? 690 LYS A CE  1 
ATOM   4665  N NZ  . LYS A 1 690 ? 101.932 90.394  100.316 1.00 108.72 ? 690 LYS A NZ  1 
ATOM   4666  N N   . VAL A 1 691 ? 105.769 94.237  105.064 1.00 101.04 ? 691 VAL A N   1 
ATOM   4667  C CA  . VAL A 1 691 ? 106.380 95.441  104.463 1.00 102.30 ? 691 VAL A CA  1 
ATOM   4668  C C   . VAL A 1 691 ? 106.657 95.284  102.962 1.00 104.14 ? 691 VAL A C   1 
ATOM   4669  O O   . VAL A 1 691 ? 106.827 96.280  102.261 1.00 100.50 ? 691 VAL A O   1 
ATOM   4670  C CB  . VAL A 1 691 ? 107.639 95.873  105.237 1.00 97.93  ? 691 VAL A CB  1 
ATOM   4671  C CG1 . VAL A 1 691 ? 107.271 96.369  106.633 1.00 93.64  ? 691 VAL A CG1 1 
ATOM   4672  C CG2 . VAL A 1 691 ? 108.683 94.773  105.374 1.00 97.34  ? 691 VAL A CG2 1 
ATOM   4673  N N   . GLY A 1 692 ? 106.658 94.052  102.448 1.00 116.75 ? 692 GLY A N   1 
ATOM   4674  C CA  . GLY A 1 692 ? 106.907 93.742  101.040 1.00 115.94 ? 692 GLY A CA  1 
ATOM   4675  C C   . GLY A 1 692 ? 107.037 92.239  100.773 1.00 120.33 ? 692 GLY A C   1 
ATOM   4676  O O   . GLY A 1 692 ? 106.499 91.417  101.519 1.00 120.43 ? 692 GLY A O   1 
ATOM   4677  N N   . THR A 1 693 ? 107.765 91.871  99.713  1.00 132.06 ? 693 THR A N   1 
ATOM   4678  C CA  . THR A 1 693 ? 108.074 90.475  99.335  1.00 132.63 ? 693 THR A CA  1 
ATOM   4679  C C   . THR A 1 693 ? 109.562 90.166  99.553  1.00 130.69 ? 693 THR A C   1 
ATOM   4680  O O   . THR A 1 693 ? 110.427 90.924  99.112  1.00 129.54 ? 693 THR A O   1 
ATOM   4681  C CB  . THR A 1 693 ? 107.653 90.193  97.883  1.00 130.11 ? 693 THR A CB  1 
ATOM   4682  O OG1 . THR A 1 693 ? 106.286 90.502  97.721  1.00 128.04 ? 693 THR A OG1 1 
ATOM   4683  C CG2 . THR A 1 693 ? 107.820 88.727  97.492  1.00 127.99 ? 693 THR A CG2 1 
ATOM   4684  N N   . ARG A 1 694 ? 109.879 89.067  100.254 1.00 133.79 ? 694 ARG A N   1 
ATOM   4685  C CA  . ARG A 1 694 ? 111.241 88.728  100.708 1.00 133.33 ? 694 ARG A CA  1 
ATOM   4686  C C   . ARG A 1 694 ? 112.124 88.195  99.571  1.00 132.70 ? 694 ARG A C   1 
ATOM   4687  O O   . ARG A 1 694 ? 111.840 87.139  99.005  1.00 131.37 ? 694 ARG A O   1 
ATOM   4688  C CB  . ARG A 1 694 ? 111.150 87.759  101.902 1.00 132.78 ? 694 ARG A CB  1 
ATOM   4689  C CG  . ARG A 1 694 ? 112.444 87.757  102.728 1.00 132.47 ? 694 ARG A CG  1 
ATOM   4690  C CD  . ARG A 1 694 ? 112.303 86.827  103.939 1.00 132.41 ? 694 ARG A CD  1 
ATOM   4691  N NE  . ARG A 1 694 ? 113.425 86.981  104.884 1.00 135.36 ? 694 ARG A NE  1 
ATOM   4692  C CZ  . ARG A 1 694 ? 113.659 86.251  105.960 1.00 135.14 ? 694 ARG A CZ  1 
ATOM   4693  N NH1 . ARG A 1 694 ? 114.633 86.547  106.767 1.00 132.21 ? 694 ARG A NH1 1 
ATOM   4694  N NH2 . ARG A 1 694 ? 112.935 85.213  106.263 1.00 135.32 ? 694 ARG A NH2 1 
ATOM   4695  N N   . PRO A 1 699 ? 106.148 86.095  102.665 1.00 127.01 ? 699 PRO A N   1 
ATOM   4696  C CA  . PRO A 1 699 ? 106.495 87.476  102.366 1.00 128.10 ? 699 PRO A CA  1 
ATOM   4697  C C   . PRO A 1 699 ? 107.524 88.082  103.331 1.00 129.27 ? 699 PRO A C   1 
ATOM   4698  O O   . PRO A 1 699 ? 108.057 87.414  104.216 1.00 125.77 ? 699 PRO A O   1 
ATOM   4699  C CB  . PRO A 1 699 ? 105.166 88.234  102.381 1.00 125.10 ? 699 PRO A CB  1 
ATOM   4700  C CG  . PRO A 1 699 ? 104.141 87.165  102.036 1.00 125.90 ? 699 PRO A CG  1 
ATOM   4701  C CD  . PRO A 1 699 ? 104.715 85.919  102.695 1.00 125.87 ? 699 PRO A CD  1 
ATOM   4702  N N   . ASP A 1 700 ? 107.828 89.369  103.154 1.00 121.72 ? 700 ASP A N   1 
ATOM   4703  C CA  . ASP A 1 700 ? 108.677 90.128  104.072 1.00 120.33 ? 700 ASP A CA  1 
ATOM   4704  C C   . ASP A 1 700 ? 107.815 90.663  105.220 1.00 115.88 ? 700 ASP A C   1 
ATOM   4705  O O   . ASP A 1 700 ? 107.267 91.762  105.154 1.00 111.97 ? 700 ASP A O   1 
ATOM   4706  C CB  . ASP A 1 700 ? 109.418 91.230  103.297 1.00 119.14 ? 700 ASP A CB  1 
ATOM   4707  C CG  . ASP A 1 700 ? 110.582 91.853  104.067 1.00 121.12 ? 700 ASP A CG  1 
ATOM   4708  O OD1 . ASP A 1 700 ? 110.874 91.445  105.209 1.00 119.32 ? 700 ASP A OD1 1 
ATOM   4709  O OD2 . ASP A 1 700 ? 111.247 92.754  103.513 1.00 119.03 ? 700 ASP A OD2 1 
ATOM   4710  N N   . GLU A 1 701 ? 107.622 89.837  106.248 1.00 106.86 ? 701 GLU A N   1 
ATOM   4711  C CA  . GLU A 1 701 ? 106.831 90.156  107.436 1.00 108.21 ? 701 GLU A CA  1 
ATOM   4712  C C   . GLU A 1 701 ? 107.759 90.378  108.630 1.00 108.03 ? 701 GLU A C   1 
ATOM   4713  O O   . GLU A 1 701 ? 108.587 89.522  108.951 1.00 107.92 ? 701 GLU A O   1 
ATOM   4714  C CB  . GLU A 1 701 ? 105.806 89.050  107.731 1.00 109.74 ? 701 GLU A CB  1 
ATOM   4715  C CG  . GLU A 1 701 ? 104.782 88.899  106.599 1.00 112.17 ? 701 GLU A CG  1 
ATOM   4716  C CD  . GLU A 1 701 ? 103.712 87.833  106.883 1.00 112.78 ? 701 GLU A CD  1 
ATOM   4717  O OE1 . GLU A 1 701 ? 104.023 86.785  107.492 1.00 111.07 ? 701 GLU A OE1 1 
ATOM   4718  O OE2 . GLU A 1 701 ? 102.546 88.030  106.476 1.00 110.37 ? 701 GLU A OE2 1 
ATOM   4719  N N   . ARG A 1 702 ? 107.625 91.565  109.257 1.00 90.58  ? 702 ARG A N   1 
ATOM   4720  C CA  . ARG A 1 702 ? 108.564 91.977  110.339 1.00 85.40  ? 702 ARG A CA  1 
ATOM   4721  C C   . ARG A 1 702 ? 107.890 92.687  111.500 1.00 88.29  ? 702 ARG A C   1 
ATOM   4722  O O   . ARG A 1 702 ? 106.879 93.382  111.273 1.00 93.38  ? 702 ARG A O   1 
ATOM   4723  C CB  . ARG A 1 702 ? 109.516 93.035  109.778 1.00 82.94  ? 702 ARG A CB  1 
ATOM   4724  C CG  . ARG A 1 702 ? 110.246 92.610  108.510 1.00 83.69  ? 702 ARG A CG  1 
ATOM   4725  C CD  . ARG A 1 702 ? 111.361 93.608  108.249 1.00 87.72  ? 702 ARG A CD  1 
ATOM   4726  N NE  . ARG A 1 702 ? 111.908 93.432  106.910 1.00 89.74  ? 702 ARG A NE  1 
ATOM   4727  C CZ  . ARG A 1 702 ? 112.822 94.224  106.361 1.00 88.69  ? 702 ARG A CZ  1 
ATOM   4728  N NH1 . ARG A 1 702 ? 113.255 93.984  105.136 1.00 85.82  ? 702 ARG A NH1 1 
ATOM   4729  N NH2 . ARG A 1 702 ? 113.297 95.254  107.038 1.00 88.56  ? 702 ARG A NH2 1 
ATOM   4730  N N   . TRP A 1 703 ? 108.443 92.512  112.696 1.00 86.67  ? 703 TRP A N   1 
ATOM   4731  C CA  . TRP A 1 703 ? 107.997 93.271  113.858 1.00 87.08  ? 703 TRP A CA  1 
ATOM   4732  C C   . TRP A 1 703 ? 108.400 94.733  113.702 1.00 85.76  ? 703 TRP A C   1 
ATOM   4733  O O   . TRP A 1 703 ? 109.516 95.136  114.014 1.00 88.00  ? 703 TRP A O   1 
ATOM   4734  C CB  . TRP A 1 703 ? 108.503 92.604  115.130 1.00 81.52  ? 703 TRP A CB  1 
ATOM   4735  C CG  . TRP A 1 703 ? 107.719 91.370  115.432 1.00 83.41  ? 703 TRP A CG  1 
ATOM   4736  C CD1 . TRP A 1 703 ? 107.885 90.167  114.844 1.00 85.01  ? 703 TRP A CD1 1 
ATOM   4737  C CD2 . TRP A 1 703 ? 106.549 91.237  116.290 1.00 87.89  ? 703 TRP A CD2 1 
ATOM   4738  N NE1 . TRP A 1 703 ? 106.909 89.301  115.286 1.00 86.51  ? 703 TRP A NE1 1 
ATOM   4739  C CE2 . TRP A 1 703 ? 106.061 89.904  116.183 1.00 90.88  ? 703 TRP A CE2 1 
ATOM   4740  C CE3 . TRP A 1 703 ? 105.856 92.104  117.158 1.00 86.95  ? 703 TRP A CE3 1 
ATOM   4741  C CZ2 . TRP A 1 703 ? 104.942 89.455  116.895 1.00 89.93  ? 703 TRP A CZ2 1 
ATOM   4742  C CZ3 . TRP A 1 703 ? 104.745 91.657  117.893 1.00 88.19  ? 703 TRP A CZ3 1 
ATOM   4743  C CH2 . TRP A 1 703 ? 104.285 90.338  117.765 1.00 87.74  ? 703 TRP A CH2 1 
ATOM   4744  N N   . CYS A 1 704 ? 107.473 95.507  113.151 1.00 77.20  ? 704 CYS A N   1 
ATOM   4745  C CA  . CYS A 1 704 ? 107.609 96.919  112.851 1.00 71.57  ? 704 CYS A CA  1 
ATOM   4746  C C   . CYS A 1 704 ? 106.983 97.786  113.936 1.00 75.70  ? 704 CYS A C   1 
ATOM   4747  O O   . CYS A 1 704 ? 105.962 97.436  114.520 1.00 81.00  ? 704 CYS A O   1 
ATOM   4748  C CB  . CYS A 1 704 ? 106.932 97.217  111.516 1.00 83.40  ? 704 CYS A CB  1 
ATOM   4749  S SG  . CYS A 1 704 ? 107.997 96.716  110.154 1.00 95.63  ? 704 CYS A SG  1 
ATOM   4750  N N   . PHE A 1 705 ? 107.564 98.951  114.168 1.00 63.22  ? 705 PHE A N   1 
ATOM   4751  C CA  . PHE A 1 705 ? 107.102 99.934  115.129 1.00 61.68  ? 705 PHE A CA  1 
ATOM   4752  C C   . PHE A 1 705 ? 106.856 101.277 114.450 1.00 61.21  ? 705 PHE A C   1 
ATOM   4753  O O   . PHE A 1 705 ? 107.755 101.835 113.831 1.00 66.91  ? 705 PHE A O   1 
ATOM   4754  C CB  . PHE A 1 705 ? 108.159 99.977  116.221 1.00 68.31  ? 705 PHE A CB  1 
ATOM   4755  C CG  . PHE A 1 705 ? 108.004 101.058 117.253 1.00 66.77  ? 705 PHE A CG  1 
ATOM   4756  C CD1 . PHE A 1 705 ? 107.153 100.869 118.355 1.00 59.21  ? 705 PHE A CD1 1 
ATOM   4757  C CD2 . PHE A 1 705 ? 108.754 102.235 117.126 1.00 64.46  ? 705 PHE A CD2 1 
ATOM   4758  C CE1 . PHE A 1 705 ? 107.044 101.870 119.329 1.00 56.09  ? 705 PHE A CE1 1 
ATOM   4759  C CE2 . PHE A 1 705 ? 108.657 103.225 118.107 1.00 69.75  ? 705 PHE A CE2 1 
ATOM   4760  C CZ  . PHE A 1 705 ? 107.796 103.043 119.201 1.00 68.11  ? 705 PHE A CZ  1 
ATOM   4761  N N   . ARG A 1 706 ? 105.616 101.777 114.575 1.00 67.78  ? 706 ARG A N   1 
ATOM   4762  C CA  . ARG A 1 706 ? 105.186 103.009 113.854 1.00 67.96  ? 706 ARG A CA  1 
ATOM   4763  C C   . ARG A 1 706 ? 105.557 104.292 114.591 1.00 65.84  ? 706 ARG A C   1 
ATOM   4764  O O   . ARG A 1 706 ? 105.100 104.473 115.737 1.00 76.65  ? 706 ARG A O   1 
ATOM   4765  C CB  . ARG A 1 706 ? 103.667 102.947 113.662 1.00 67.24  ? 706 ARG A CB  1 
ATOM   4766  C CG  . ARG A 1 706 ? 103.133 104.132 112.851 1.00 69.10  ? 706 ARG A CG  1 
ATOM   4767  C CD  . ARG A 1 706 ? 101.623 104.018 112.631 1.00 70.91  ? 706 ARG A CD  1 
ATOM   4768  N NE  . ARG A 1 706 ? 101.301 102.980 111.640 1.00 74.10  ? 706 ARG A NE  1 
ATOM   4769  C CZ  . ARG A 1 706 ? 101.148 101.691 111.921 1.00 77.43  ? 706 ARG A CZ  1 
ATOM   4770  N NH1 . ARG A 1 706 ? 100.860 100.833 110.956 1.00 71.10  ? 706 ARG A NH1 1 
ATOM   4771  N NH2 . ARG A 1 706 ? 101.288 101.263 113.163 1.00 79.03  ? 706 ARG A NH2 1 
ATOM   4772  N N   . VAL A 1 707 ? 106.351 105.136 113.952 1.00 61.83  ? 707 VAL A N   1 
ATOM   4773  C CA  . VAL A 1 707 ? 106.743 106.465 114.436 1.00 64.70  ? 707 VAL A CA  1 
ATOM   4774  C C   . VAL A 1 707 ? 106.091 107.515 113.546 1.00 72.48  ? 707 VAL A C   1 
ATOM   4775  O O   . VAL A 1 707 ? 106.066 107.365 112.330 1.00 81.04  ? 707 VAL A O   1 
ATOM   4776  C CB  . VAL A 1 707 ? 108.269 106.623 114.441 1.00 71.93  ? 707 VAL A CB  1 
ATOM   4777  C CG1 . VAL A 1 707 ? 108.727 107.997 114.932 1.00 69.30  ? 707 VAL A CG1 1 
ATOM   4778  C CG2 . VAL A 1 707 ? 108.959 105.573 115.315 1.00 77.18  ? 707 VAL A CG2 1 
ATOM   4779  N N   . GLU A 1 708 ? 105.558 108.580 114.135 1.00 80.50  ? 708 GLU A N   1 
ATOM   4780  C CA  . GLU A 1 708 ? 104.981 109.717 113.416 1.00 72.25  ? 708 GLU A CA  1 
ATOM   4781  C C   . GLU A 1 708 ? 105.837 110.958 113.688 1.00 73.75  ? 708 GLU A C   1 
ATOM   4782  O O   . GLU A 1 708 ? 105.957 111.391 114.829 1.00 78.33  ? 708 GLU A O   1 
ATOM   4783  C CB  . GLU A 1 708 ? 103.531 109.941 113.858 1.00 71.20  ? 708 GLU A CB  1 
ATOM   4784  C CG  . GLU A 1 708 ? 102.663 108.670 113.864 1.00 76.59  ? 708 GLU A CG  1 
ATOM   4785  C CD  . GLU A 1 708 ? 101.246 108.914 114.397 1.00 87.34  ? 708 GLU A CD  1 
ATOM   4786  O OE1 . GLU A 1 708 ? 101.054 109.811 115.250 1.00 90.26  ? 708 GLU A OE1 1 
ATOM   4787  O OE2 . GLU A 1 708 ? 100.326 108.167 113.999 1.00 85.77  ? 708 GLU A OE2 1 
ATOM   4788  N N   . GLU A 1 709 ? 106.453 111.528 112.659 1.00 87.74  ? 709 GLU A N   1 
ATOM   4789  C CA  . GLU A 1 709 ? 107.290 112.724 112.761 1.00 91.73  ? 709 GLU A CA  1 
ATOM   4790  C C   . GLU A 1 709 ? 106.568 113.917 112.140 1.00 96.11  ? 709 GLU A C   1 
ATOM   4791  O O   . GLU A 1 709 ? 106.178 113.857 110.977 1.00 99.11  ? 709 GLU A O   1 
ATOM   4792  C CB  . GLU A 1 709 ? 108.643 112.479 112.067 1.00 89.53  ? 709 GLU A CB  1 
ATOM   4793  C CG  . GLU A 1 709 ? 109.544 113.727 112.075 1.00 90.00  ? 709 GLU A CG  1 
ATOM   4794  C CD  . GLU A 1 709 ? 110.851 113.595 111.274 1.00 100.24 ? 709 GLU A CD  1 
ATOM   4795  O OE1 . GLU A 1 709 ? 111.106 112.540 110.652 1.00 100.62 ? 709 GLU A OE1 1 
ATOM   4796  O OE2 . GLU A 1 709 ? 111.632 114.574 111.263 1.00 100.48 ? 709 GLU A OE2 1 
ATOM   4797  N N   . VAL A 1 710 ? 106.445 115.020 112.879 1.00 87.97  ? 710 VAL A N   1 
ATOM   4798  C CA  . VAL A 1 710 ? 106.020 116.319 112.350 1.00 83.93  ? 710 VAL A CA  1 
ATOM   4799  C C   . VAL A 1 710 ? 107.236 117.233 112.306 1.00 85.74  ? 710 VAL A C   1 
ATOM   4800  O O   . VAL A 1 710 ? 107.879 117.452 113.331 1.00 84.32  ? 710 VAL A O   1 
ATOM   4801  C CB  . VAL A 1 710 ? 104.914 116.944 113.210 1.00 83.01  ? 710 VAL A CB  1 
ATOM   4802  C CG1 . VAL A 1 710 ? 104.396 118.229 112.563 1.00 85.34  ? 710 VAL A CG1 1 
ATOM   4803  C CG2 . VAL A 1 710 ? 103.737 115.991 113.422 1.00 83.87  ? 710 VAL A CG2 1 
ATOM   4804  N N   . ASN A 1 711 ? 107.575 117.774 111.136 1.00 87.87  ? 711 ASN A N   1 
ATOM   4805  C CA  . ASN A 1 711 ? 108.800 118.552 110.958 1.00 84.19  ? 711 ASN A CA  1 
ATOM   4806  C C   . ASN A 1 711 ? 108.627 119.647 109.895 1.00 87.58  ? 711 ASN A C   1 
ATOM   4807  O O   . ASN A 1 711 ? 109.049 119.509 108.749 1.00 91.60  ? 711 ASN A O   1 
ATOM   4808  C CB  . ASN A 1 711 ? 109.940 117.568 110.656 1.00 86.19  ? 711 ASN A CB  1 
ATOM   4809  C CG  . ASN A 1 711 ? 111.321 118.174 110.796 1.00 85.84  ? 711 ASN A CG  1 
ATOM   4810  O OD1 . ASN A 1 711 ? 111.524 119.377 110.714 1.00 82.47  ? 711 ASN A OD1 1 
ATOM   4811  N ND2 . ASN A 1 711 ? 112.311 117.351 111.033 1.00 86.59  ? 711 ASN A ND2 1 
ATOM   4812  N N   . TRP A 1 712 ? 108.000 120.759 110.282 1.00 86.47  ? 712 TRP A N   1 
ATOM   4813  C CA  . TRP A 1 712 ? 107.823 121.930 109.424 1.00 86.45  ? 712 TRP A CA  1 
ATOM   4814  C C   . TRP A 1 712 ? 109.156 122.484 108.918 1.00 86.82  ? 712 TRP A C   1 
ATOM   4815  O O   . TRP A 1 712 ? 109.303 122.724 107.725 1.00 85.16  ? 712 TRP A O   1 
ATOM   4816  C CB  . TRP A 1 712 ? 107.077 123.017 110.200 1.00 85.35  ? 712 TRP A CB  1 
ATOM   4817  C CG  . TRP A 1 712 ? 105.607 122.820 110.375 1.00 87.86  ? 712 TRP A CG  1 
ATOM   4818  C CD1 . TRP A 1 712 ? 105.006 122.098 111.347 1.00 85.41  ? 712 TRP A CD1 1 
ATOM   4819  C CD2 . TRP A 1 712 ? 104.528 123.395 109.579 1.00 88.43  ? 712 TRP A CD2 1 
ATOM   4820  N NE1 . TRP A 1 712 ? 103.636 122.179 111.201 1.00 88.31  ? 712 TRP A NE1 1 
ATOM   4821  C CE2 . TRP A 1 712 ? 103.286 122.988 110.143 1.00 90.52  ? 712 TRP A CE2 1 
ATOM   4822  C CE3 . TRP A 1 712 ? 104.479 124.254 108.465 1.00 81.59  ? 712 TRP A CE3 1 
ATOM   4823  C CZ2 . TRP A 1 712 ? 102.056 123.412 109.622 1.00 84.27  ? 712 TRP A CZ2 1 
ATOM   4824  C CZ3 . TRP A 1 712 ? 103.249 124.677 107.931 1.00 83.54  ? 712 TRP A CZ3 1 
ATOM   4825  C CH2 . TRP A 1 712 ? 102.041 124.262 108.507 1.00 83.24  ? 712 TRP A CH2 1 
ATOM   4826  N N   . ALA A 1 713 ? 110.145 122.642 109.798 1.00 94.42  ? 713 ALA A N   1 
ATOM   4827  C CA  . ALA A 1 713 ? 111.430 123.241 109.447 1.00 91.36  ? 713 ALA A CA  1 
ATOM   4828  C C   . ALA A 1 713 ? 112.170 122.471 108.338 1.00 92.22  ? 713 ALA A C   1 
ATOM   4829  O O   . ALA A 1 713 ? 112.726 123.093 107.437 1.00 92.30  ? 713 ALA A O   1 
ATOM   4830  C CB  . ALA A 1 713 ? 112.269 123.343 110.724 1.00 85.85  ? 713 ALA A CB  1 
ATOM   4831  N N   . ALA A 1 714 ? 112.153 121.133 108.360 1.00 90.05  ? 714 ALA A N   1 
ATOM   4832  C CA  . ALA A 1 714 ? 112.726 120.322 107.287 1.00 87.12  ? 714 ALA A CA  1 
ATOM   4833  C C   . ALA A 1 714 ? 111.827 120.274 106.044 1.00 88.26  ? 714 ALA A C   1 
ATOM   4834  O O   . ALA A 1 714 ? 112.322 120.338 104.925 1.00 90.67  ? 714 ALA A O   1 
ATOM   4835  C CB  . ALA A 1 714 ? 112.990 118.912 107.817 1.00 84.78  ? 714 ALA A CB  1 
ATOM   4836  N N   . TRP A 1 715 ? 110.510 120.178 106.216 1.00 84.17  ? 715 TRP A N   1 
ATOM   4837  C CA  . TRP A 1 715 ? 109.559 120.070 105.107 1.00 84.69  ? 715 TRP A CA  1 
ATOM   4838  C C   . TRP A 1 715 ? 109.495 121.327 104.246 1.00 88.46  ? 715 TRP A C   1 
ATOM   4839  O O   . TRP A 1 715 ? 109.521 121.226 103.021 1.00 89.67  ? 715 TRP A O   1 
ATOM   4840  C CB  . TRP A 1 715 ? 108.180 119.728 105.662 1.00 81.95  ? 715 TRP A CB  1 
ATOM   4841  C CG  . TRP A 1 715 ? 107.052 119.830 104.691 1.00 83.22  ? 715 TRP A CG  1 
ATOM   4842  C CD1 . TRP A 1 715 ? 106.832 119.007 103.643 1.00 81.89  ? 715 TRP A CD1 1 
ATOM   4843  C CD2 . TRP A 1 715 ? 105.984 120.815 104.656 1.00 88.24  ? 715 TRP A CD2 1 
ATOM   4844  N NE1 . TRP A 1 715 ? 105.683 119.394 102.989 1.00 80.87  ? 715 TRP A NE1 1 
ATOM   4845  C CE2 . TRP A 1 715 ? 105.092 120.477 103.601 1.00 86.35  ? 715 TRP A CE2 1 
ATOM   4846  C CE3 . TRP A 1 715 ? 105.663 121.945 105.433 1.00 81.81  ? 715 TRP A CE3 1 
ATOM   4847  C CZ2 . TRP A 1 715 ? 103.919 121.193 103.353 1.00 76.99  ? 715 TRP A CZ2 1 
ATOM   4848  C CZ3 . TRP A 1 715 ? 104.499 122.685 105.177 1.00 78.21  ? 715 TRP A CZ3 1 
ATOM   4849  C CH2 . TRP A 1 715 ? 103.619 122.304 104.158 1.00 76.26  ? 715 TRP A CH2 1 
ATOM   4850  N N   . GLU A 1 716 ? 109.480 122.517 104.842 1.00 100.43 ? 716 GLU A N   1 
ATOM   4851  C CA  . GLU A 1 716 ? 109.371 123.773 104.099 1.00 96.93  ? 716 GLU A CA  1 
ATOM   4852  C C   . GLU A 1 716 ? 110.529 124.004 103.121 1.00 99.64  ? 716 GLU A C   1 
ATOM   4853  O O   . GLU A 1 716 ? 110.347 124.610 102.069 1.00 99.53  ? 716 GLU A O   1 
ATOM   4854  C CB  . GLU A 1 716 ? 109.278 124.948 105.067 1.00 99.73  ? 716 GLU A CB  1 
ATOM   4855  C CG  . GLU A 1 716 ? 107.889 125.016 105.698 1.00 104.20 ? 716 GLU A CG  1 
ATOM   4856  C CD  . GLU A 1 716 ? 107.743 126.325 106.467 1.00 106.26 ? 716 GLU A CD  1 
ATOM   4857  O OE1 . GLU A 1 716 ? 108.199 126.413 107.623 1.00 103.79 ? 716 GLU A OE1 1 
ATOM   4858  O OE2 . GLU A 1 716 ? 107.193 127.285 105.888 1.00 102.75 ? 716 GLU A OE2 1 
ATOM   4859  N N   . LYS A 1 717 ? 111.710 123.461 103.429 1.00 102.47 ? 717 LYS A N   1 
ATOM   4860  C CA  . LYS A 1 717 ? 112.901 123.499 102.569 1.00 102.53 ? 717 LYS A CA  1 
ATOM   4861  C C   . LYS A 1 717 ? 112.775 122.626 101.311 1.00 100.79 ? 717 LYS A C   1 
ATOM   4862  O O   . LYS A 1 717 ? 113.562 122.783 100.383 1.00 101.92 ? 717 LYS A O   1 
ATOM   4863  C CB  . LYS A 1 717 ? 114.128 123.120 103.414 1.00 98.34  ? 717 LYS A CB  1 
ATOM   4864  C CG  . LYS A 1 717 ? 114.361 124.140 104.540 1.00 100.11 ? 717 LYS A CG  1 
ATOM   4865  C CD  . LYS A 1 717 ? 115.475 123.705 105.497 1.00 103.56 ? 717 LYS A CD  1 
ATOM   4866  C CE  . LYS A 1 717 ? 115.543 124.709 106.653 1.00 101.38 ? 717 LYS A CE  1 
ATOM   4867  N NZ  . LYS A 1 717 ? 116.587 124.343 107.638 1.00 98.96  ? 717 LYS A NZ  1 
ATOM   4868  N N   . THR A 1 718 ? 111.779 121.738 101.252 1.00 96.19  ? 718 THR A N   1 
ATOM   4869  C CA  . THR A 1 718 ? 111.469 120.890 100.083 1.00 98.31  ? 718 THR A CA  1 
ATOM   4870  C C   . THR A 1 718 ? 110.383 121.465 99.164  1.00 98.85  ? 718 THR A C   1 
ATOM   4871  O O   . THR A 1 718 ? 110.145 120.921 98.086  1.00 97.12  ? 718 THR A O   1 
ATOM   4872  C CB  . THR A 1 718 ? 111.070 119.465 100.504 1.00 103.64 ? 718 THR A CB  1 
ATOM   4873  O OG1 . THR A 1 718 ? 109.771 119.407 101.051 1.00 101.46 ? 718 THR A OG1 1 
ATOM   4874  C CG2 . THR A 1 718 ? 112.029 118.855 101.519 1.00 99.41  ? 718 THR A CG2 1 
ATOM   4875  N N   . LEU A 1 719 ? 109.704 122.548 99.556  1.00 100.28 ? 719 LEU A N   1 
ATOM   4876  C CA  . LEU A 1 719 ? 108.597 123.122 98.788  1.00 103.20 ? 719 LEU A CA  1 
ATOM   4877  C C   . LEU A 1 719 ? 109.066 123.704 97.443  1.00 100.32 ? 719 LEU A C   1 
ATOM   4878  O O   . LEU A 1 719 ? 109.718 124.750 97.381  1.00 99.11  ? 719 LEU A O   1 
ATOM   4879  C CB  . LEU A 1 719 ? 107.824 124.141 99.650  1.00 100.14 ? 719 LEU A CB  1 
ATOM   4880  C CG  . LEU A 1 719 ? 107.232 123.569 100.952 1.00 96.94  ? 719 LEU A CG  1 
ATOM   4881  C CD1 . LEU A 1 719 ? 106.489 124.656 101.720 1.00 97.03  ? 719 LEU A CD1 1 
ATOM   4882  C CD2 . LEU A 1 719 ? 106.252 122.436 100.706 1.00 92.34  ? 719 LEU A CD2 1 
ATOM   4883  N N   . ARG B 1 74  ? 83.852  91.202  89.221  1.00 168.48 ? 74  ARG B N   1 
ATOM   4884  C CA  . ARG B 1 74  ? 83.119  91.395  90.501  1.00 168.86 ? 74  ARG B CA  1 
ATOM   4885  C C   . ARG B 1 74  ? 83.021  92.896  90.796  1.00 170.27 ? 74  ARG B C   1 
ATOM   4886  O O   . ARG B 1 74  ? 81.904  93.318  91.152  1.00 170.55 ? 74  ARG B O   1 
ATOM   4887  C CB  . ARG B 1 74  ? 83.818  90.617  91.636  1.00 168.45 ? 74  ARG B CB  1 
ATOM   4888  N N   . PHE B 1 75  ? 84.092  93.695  90.682  1.00 167.79 ? 75  PHE B N   1 
ATOM   4889  C CA  . PHE B 1 75  ? 84.107  95.122  91.095  1.00 166.40 ? 75  PHE B CA  1 
ATOM   4890  C C   . PHE B 1 75  ? 83.707  95.372  92.565  1.00 165.82 ? 75  PHE B C   1 
ATOM   4891  O O   . PHE B 1 75  ? 82.964  96.295  92.904  1.00 165.60 ? 75  PHE B O   1 
ATOM   4892  C CB  . PHE B 1 75  ? 83.376  96.023  90.086  1.00 166.49 ? 75  PHE B CB  1 
ATOM   4893  C CG  . PHE B 1 75  ? 84.147  96.231  88.803  1.00 167.45 ? 75  PHE B CG  1 
ATOM   4894  C CD1 . PHE B 1 75  ? 85.311  97.023  88.809  1.00 166.84 ? 75  PHE B CD1 1 
ATOM   4895  C CD2 . PHE B 1 75  ? 83.714  95.633  87.606  1.00 166.78 ? 75  PHE B CD2 1 
ATOM   4896  C CE1 . PHE B 1 75  ? 86.039  97.220  87.625  1.00 166.99 ? 75  PHE B CE1 1 
ATOM   4897  C CE2 . PHE B 1 75  ? 84.448  95.822  86.426  1.00 166.30 ? 75  PHE B CE2 1 
ATOM   4898  C CZ  . PHE B 1 75  ? 85.603  96.620  86.432  1.00 166.85 ? 75  PHE B CZ  1 
ATOM   4899  N N   . ASP B 1 76  ? 84.251  94.584  93.373  1.00 161.82 ? 76  ASP B N   1 
ATOM   4900  C CA  . ASP B 1 76  ? 84.346  94.919  94.794  1.00 161.88 ? 76  ASP B CA  1 
ATOM   4901  C C   . ASP B 1 76  ? 85.368  96.052  95.041  1.00 162.31 ? 76  ASP B C   1 
ATOM   4902  O O   . ASP B 1 76  ? 86.093  96.493  94.139  1.00 162.20 ? 76  ASP B O   1 
ATOM   4903  C CB  . ASP B 1 76  ? 84.661  93.643  95.602  1.00 160.98 ? 76  ASP B CB  1 
ATOM   4904  C CG  . ASP B 1 76  ? 85.955  92.902  95.220  1.00 161.24 ? 76  ASP B CG  1 
ATOM   4905  O OD1 . ASP B 1 76  ? 86.861  93.506  94.613  1.00 161.92 ? 76  ASP B OD1 1 
ATOM   4906  O OD2 . ASP B 1 76  ? 86.044  91.697  95.545  1.00 159.88 ? 76  ASP B OD2 1 
ATOM   4907  N N   . ARG B 1 77  ? 85.459  96.477  96.307  1.00 152.29 ? 77  ARG B N   1 
ATOM   4908  C CA  . ARG B 1 77  ? 86.374  97.586  96.697  1.00 153.02 ? 77  ARG B CA  1 
ATOM   4909  C C   . ARG B 1 77  ? 87.837  97.238  96.430  1.00 152.39 ? 77  ARG B C   1 
ATOM   4910  O O   . ARG B 1 77  ? 88.573  98.128  95.960  1.00 152.53 ? 77  ARG B O   1 
ATOM   4911  C CB  . ARG B 1 77  ? 86.219  97.834  98.202  1.00 150.72 ? 77  ARG B CB  1 
ATOM   4912  C CG  . ARG B 1 77  ? 87.088  98.996  98.706  1.00 152.66 ? 77  ARG B CG  1 
ATOM   4913  C CD  . ARG B 1 77  ? 87.204  98.997  100.227 1.00 152.24 ? 77  ARG B CD  1 
ATOM   4914  N NE  . ARG B 1 77  ? 87.980  97.842  100.704 1.00 152.20 ? 77  ARG B NE  1 
ATOM   4915  C CZ  . ARG B 1 77  ? 88.315  97.634  101.972 1.00 151.69 ? 77  ARG B CZ  1 
ATOM   4916  N NH1 . ARG B 1 77  ? 89.016  96.563  102.303 1.00 150.82 ? 77  ARG B NH1 1 
ATOM   4917  N NH2 . ARG B 1 77  ? 87.952  98.498  102.903 1.00 150.21 ? 77  ARG B NH2 1 
ATOM   4918  N N   . ASP B 1 78  ? 88.243  96.000  96.710  1.00 152.83 ? 78  ASP B N   1 
ATOM   4919  C CA  . ASP B 1 78  ? 89.651  95.616  96.617  1.00 152.68 ? 78  ASP B CA  1 
ATOM   4920  C C   . ASP B 1 78  ? 90.128  95.511  95.155  1.00 152.32 ? 78  ASP B C   1 
ATOM   4921  O O   . ASP B 1 78  ? 91.262  95.906  94.852  1.00 153.06 ? 78  ASP B O   1 
ATOM   4922  C CB  . ASP B 1 78  ? 89.895  94.329  97.414  1.00 154.38 ? 78  ASP B CB  1 
ATOM   4923  C CG  . ASP B 1 78  ? 89.544  94.422  98.913  1.00 155.02 ? 78  ASP B CG  1 
ATOM   4924  O OD1 . ASP B 1 78  ? 89.355  95.531  99.467  1.00 156.02 ? 78  ASP B OD1 1 
ATOM   4925  O OD2 . ASP B 1 78  ? 89.480  93.352  99.560  1.00 153.83 ? 78  ASP B OD2 1 
ATOM   4926  N N   . ARG B 1 79  ? 89.261  95.120  94.205  1.00 156.28 ? 79  ARG B N   1 
ATOM   4927  C CA  . ARG B 1 79  ? 89.542  95.336  92.774  1.00 158.03 ? 79  ARG B CA  1 
ATOM   4928  C C   . ARG B 1 79  ? 89.643  96.826  92.463  1.00 158.93 ? 79  ARG B C   1 
ATOM   4929  O O   . ARG B 1 79  ? 90.647  97.254  91.909  1.00 157.44 ? 79  ARG B O   1 
ATOM   4930  C CB  . ARG B 1 79  ? 88.511  94.645  91.855  1.00 157.76 ? 79  ARG B CB  1 
ATOM   4931  C CG  . ARG B 1 79  ? 88.867  94.893  90.373  1.00 158.69 ? 79  ARG B CG  1 
ATOM   4932  C CD  . ARG B 1 79  ? 87.902  94.241  89.380  1.00 157.88 ? 79  ARG B CD  1 
ATOM   4933  N NE  . ARG B 1 79  ? 88.138  94.726  88.003  1.00 158.99 ? 79  ARG B NE  1 
ATOM   4934  C CZ  . ARG B 1 79  ? 89.038  94.293  87.138  1.00 157.86 ? 79  ARG B CZ  1 
ATOM   4935  N NH1 . ARG B 1 79  ? 89.187  94.879  85.987  1.00 157.52 ? 79  ARG B NH1 1 
ATOM   4936  N NH2 . ARG B 1 79  ? 89.812  93.281  87.392  1.00 156.82 ? 79  ARG B NH2 1 
ATOM   4937  N N   . LEU B 1 80  ? 88.637  97.634  92.803  1.00 154.57 ? 80  LEU B N   1 
ATOM   4938  C CA  . LEU B 1 80  ? 88.636  99.043  92.399  1.00 152.06 ? 80  LEU B CA  1 
ATOM   4939  C C   . LEU B 1 80  ? 89.842  99.819  92.956  1.00 151.87 ? 80  LEU B C   1 
ATOM   4940  O O   . LEU B 1 80  ? 90.516  100.527 92.215  1.00 152.02 ? 80  LEU B O   1 
ATOM   4941  C CB  . LEU B 1 80  ? 87.300  99.695  92.787  1.00 151.79 ? 80  LEU B CB  1 
ATOM   4942  C CG  . LEU B 1 80  ? 87.202  101.173 92.373  1.00 152.15 ? 80  LEU B CG  1 
ATOM   4943  C CD1 . LEU B 1 80  ? 87.414  101.368 90.879  1.00 152.64 ? 80  LEU B CD1 1 
ATOM   4944  C CD2 . LEU B 1 80  ? 85.818  101.700 92.718  1.00 151.57 ? 80  LEU B CD2 1 
ATOM   4945  N N   . PHE B 1 81  ? 90.164  99.644  94.237  1.00 144.75 ? 81  PHE B N   1 
ATOM   4946  C CA  . PHE B 1 81  ? 91.292  100.310 94.889  1.00 143.59 ? 81  PHE B CA  1 
ATOM   4947  C C   . PHE B 1 81  ? 92.638  99.877  94.301  1.00 144.20 ? 81  PHE B C   1 
ATOM   4948  O O   . PHE B 1 81  ? 93.557  100.688 94.219  1.00 145.01 ? 81  PHE B O   1 
ATOM   4949  C CB  . PHE B 1 81  ? 91.275  100.021 96.396  1.00 143.82 ? 81  PHE B CB  1 
ATOM   4950  C CG  . PHE B 1 81  ? 90.320  100.840 97.249  1.00 145.67 ? 81  PHE B CG  1 
ATOM   4951  C CD1 . PHE B 1 81  ? 89.125  101.388 96.742  1.00 145.86 ? 81  PHE B CD1 1 
ATOM   4952  C CD2 . PHE B 1 81  ? 90.646  101.049 98.598  1.00 144.08 ? 81  PHE B CD2 1 
ATOM   4953  C CE1 . PHE B 1 81  ? 88.276  102.132 97.577  1.00 145.65 ? 81  PHE B CE1 1 
ATOM   4954  C CE2 . PHE B 1 81  ? 89.801  101.800 99.427  1.00 143.96 ? 81  PHE B CE2 1 
ATOM   4955  C CZ  . PHE B 1 81  ? 88.617  102.345 98.917  1.00 145.38 ? 81  PHE B CZ  1 
ATOM   4956  N N   . SER B 1 82  ? 92.786  98.625  93.861  1.00 150.25 ? 82  SER B N   1 
ATOM   4957  C CA  . SER B 1 82  ? 94.003  98.195  93.158  1.00 149.77 ? 82  SER B CA  1 
ATOM   4958  C C   . SER B 1 82  ? 94.031  98.672  91.691  1.00 149.46 ? 82  SER B C   1 
ATOM   4959  O O   . SER B 1 82  ? 95.093  99.054  91.204  1.00 148.02 ? 82  SER B O   1 
ATOM   4960  C CB  . SER B 1 82  ? 94.215  96.686  93.313  1.00 148.64 ? 82  SER B CB  1 
ATOM   4961  O OG  . SER B 1 82  ? 93.142  95.921  92.819  1.00 149.29 ? 82  SER B OG  1 
ATOM   4962  N N   . VAL B 1 83  ? 92.883  98.783  91.010  1.00 148.73 ? 83  VAL B N   1 
ATOM   4963  C CA  . VAL B 1 83  ? 92.768  99.359  89.651  1.00 148.38 ? 83  VAL B CA  1 
ATOM   4964  C C   . VAL B 1 83  ? 93.171  100.834 89.605  1.00 148.44 ? 83  VAL B C   1 
ATOM   4965  O O   . VAL B 1 83  ? 94.084  101.197 88.862  1.00 146.48 ? 83  VAL B O   1 
ATOM   4966  C CB  . VAL B 1 83  ? 91.346  99.151  89.080  1.00 148.13 ? 83  VAL B CB  1 
ATOM   4967  C CG1 . VAL B 1 83  ? 91.032  100.021 87.857  1.00 148.82 ? 83  VAL B CG1 1 
ATOM   4968  C CG2 . VAL B 1 83  ? 91.156  97.693  88.647  1.00 148.71 ? 83  VAL B CG2 1 
ATOM   4969  N N   . VAL B 1 84  ? 92.559  101.697 90.425  1.00 146.41 ? 84  VAL B N   1 
ATOM   4970  C CA  . VAL B 1 84  ? 92.868  103.143 90.403  1.00 144.17 ? 84  VAL B CA  1 
ATOM   4971  C C   . VAL B 1 84  ? 94.291  103.462 90.874  1.00 143.65 ? 84  VAL B C   1 
ATOM   4972  O O   . VAL B 1 84  ? 94.832  104.504 90.506  1.00 142.74 ? 84  VAL B O   1 
ATOM   4973  C CB  . VAL B 1 84  ? 91.845  103.981 91.185  1.00 143.89 ? 84  VAL B CB  1 
ATOM   4974  C CG1 . VAL B 1 84  ? 90.433  103.786 90.638  1.00 143.83 ? 84  VAL B CG1 1 
ATOM   4975  C CG2 . VAL B 1 84  ? 91.859  103.719 92.691  1.00 142.29 ? 84  VAL B CG2 1 
ATOM   4976  N N   . SER B 1 85  ? 94.932  102.561 91.632  1.00 144.34 ? 85  SER B N   1 
ATOM   4977  C CA  . SER B 1 85  ? 96.337  102.718 92.038  1.00 144.57 ? 85  SER B CA  1 
ATOM   4978  C C   . SER B 1 85  ? 97.337  102.514 90.889  1.00 142.52 ? 85  SER B C   1 
ATOM   4979  O O   . SER B 1 85  ? 98.418  103.093 90.928  1.00 139.37 ? 85  SER B O   1 
ATOM   4980  C CB  . SER B 1 85  ? 96.689  101.742 93.164  1.00 142.66 ? 85  SER B CB  1 
ATOM   4981  O OG  . SER B 1 85  ? 95.883  101.950 94.310  1.00 141.96 ? 85  SER B OG  1 
ATOM   4982  N N   . ARG B 1 86  ? 96.945  101.749 89.854  1.00 150.85 ? 86  ARG B N   1 
ATOM   4983  C CA  . ARG B 1 86  ? 97.844  101.442 88.696  1.00 151.89 ? 86  ARG B CA  1 
ATOM   4984  C C   . ARG B 1 86  ? 97.852  102.589 87.677  1.00 152.15 ? 86  ARG B C   1 
ATOM   4985  O O   . ARG B 1 86  ? 98.838  102.687 86.921  1.00 150.76 ? 86  ARG B O   1 
ATOM   4986  C CB  . ARG B 1 86  ? 97.428  100.128 88.009  1.00 150.48 ? 86  ARG B CB  1 
ATOM   4987  C CG  . ARG B 1 86  ? 97.866  98.891  88.804  1.00 150.09 ? 86  ARG B CG  1 
ATOM   4988  C CD  . ARG B 1 86  ? 97.657  97.596  88.005  1.00 149.41 ? 86  ARG B CD  1 
ATOM   4989  N NE  . ARG B 1 86  ? 96.237  97.214  87.870  1.00 150.26 ? 86  ARG B NE  1 
ATOM   4990  C CZ  . ARG B 1 86  ? 95.517  96.636  88.825  1.00 150.99 ? 86  ARG B CZ  1 
ATOM   4991  N NH1 . ARG B 1 86  ? 94.249  96.333  88.605  1.00 148.99 ? 86  ARG B NH1 1 
ATOM   4992  N NH2 . ARG B 1 86  ? 96.063  96.369  89.997  1.00 151.28 ? 86  ARG B NH2 1 
ATOM   4993  N N   . GLY B 1 87  ? 96.807  103.414 87.654  1.00 153.16 ? 87  GLY B N   1 
ATOM   4994  C CA  . GLY B 1 87  ? 96.671  104.523 86.701  1.00 150.66 ? 87  GLY B CA  1 
ATOM   4995  C C   . GLY B 1 87  ? 96.177  104.118 85.305  1.00 152.76 ? 87  GLY B C   1 
ATOM   4996  O O   . GLY B 1 87  ? 96.207  104.941 84.393  1.00 150.84 ? 87  GLY B O   1 
ATOM   4997  N N   . VAL B 1 88  ? 95.715  102.875 85.120  1.00 162.08 ? 88  VAL B N   1 
ATOM   4998  C CA  . VAL B 1 88  ? 95.145  102.381 83.853  1.00 162.16 ? 88  VAL B CA  1 
ATOM   4999  C C   . VAL B 1 88  ? 93.613  102.520 83.884  1.00 161.67 ? 88  VAL B C   1 
ATOM   5000  O O   . VAL B 1 88  ? 92.962  101.818 84.658  1.00 159.71 ? 88  VAL B O   1 
ATOM   5001  C CB  . VAL B 1 88  ? 95.555  100.914 83.599  1.00 159.88 ? 88  VAL B CB  1 
ATOM   5002  C CG1 . VAL B 1 88  ? 94.959  100.378 82.293  1.00 158.45 ? 88  VAL B CG1 1 
ATOM   5003  C CG2 . VAL B 1 88  ? 97.077  100.780 83.504  1.00 158.01 ? 88  VAL B CG2 1 
ATOM   5004  N N   . PRO B 1 89  ? 93.000  103.385 83.052  1.00 159.88 ? 89  PRO B N   1 
ATOM   5005  C CA  . PRO B 1 89  ? 91.561  103.646 83.121  1.00 158.93 ? 89  PRO B CA  1 
ATOM   5006  C C   . PRO B 1 89  ? 90.709  102.508 82.546  1.00 159.23 ? 89  PRO B C   1 
ATOM   5007  O O   . PRO B 1 89  ? 89.557  102.332 82.933  1.00 157.55 ? 89  PRO B O   1 
ATOM   5008  C CB  . PRO B 1 89  ? 91.358  104.936 82.323  1.00 158.39 ? 89  PRO B CB  1 
ATOM   5009  C CG  . PRO B 1 89  ? 92.497  104.927 81.308  1.00 158.14 ? 89  PRO B CG  1 
ATOM   5010  C CD  . PRO B 1 89  ? 93.635  104.258 82.072  1.00 157.81 ? 89  PRO B CD  1 
ATOM   5011  N N   . GLU B 1 90  ? 91.254  101.723 81.616  1.00 163.61 ? 90  GLU B N   1 
ATOM   5012  C CA  . GLU B 1 90  ? 90.480  100.731 80.853  1.00 162.84 ? 90  GLU B CA  1 
ATOM   5013  C C   . GLU B 1 90  ? 89.982  99.553  81.711  1.00 163.88 ? 90  GLU B C   1 
ATOM   5014  O O   . GLU B 1 90  ? 88.934  98.968  81.435  1.00 163.70 ? 90  GLU B O   1 
ATOM   5015  C CB  . GLU B 1 90  ? 91.333  100.210 79.685  1.00 160.58 ? 90  GLU B CB  1 
ATOM   5016  N N   . GLU B 1 91  ? 90.682  99.228  82.801  1.00 164.32 ? 91  GLU B N   1 
ATOM   5017  C CA  . GLU B 1 91  ? 90.301  98.156  83.731  1.00 163.19 ? 91  GLU B CA  1 
ATOM   5018  C C   . GLU B 1 91  ? 89.036  98.467  84.562  1.00 163.63 ? 91  GLU B C   1 
ATOM   5019  O O   . GLU B 1 91  ? 88.513  97.576  85.233  1.00 163.04 ? 91  GLU B O   1 
ATOM   5020  C CB  . GLU B 1 91  ? 91.492  97.811  84.641  1.00 163.43 ? 91  GLU B CB  1 
ATOM   5021  C CG  . GLU B 1 91  ? 92.684  97.256  83.849  1.00 163.68 ? 91  GLU B CG  1 
ATOM   5022  C CD  . GLU B 1 91  ? 93.696  96.515  84.735  1.00 164.38 ? 91  GLU B CD  1 
ATOM   5023  O OE1 . GLU B 1 91  ? 94.076  97.025  85.812  1.00 163.80 ? 91  GLU B OE1 1 
ATOM   5024  O OE2 . GLU B 1 91  ? 94.114  95.401  84.349  1.00 163.68 ? 91  GLU B OE2 1 
ATOM   5025  N N   . LEU B 1 92  ? 88.507  99.696  84.481  1.00 164.92 ? 92  LEU B N   1 
ATOM   5026  C CA  . LEU B 1 92  ? 87.200  100.083 85.028  1.00 165.36 ? 92  LEU B CA  1 
ATOM   5027  C C   . LEU B 1 92  ? 86.015  99.569  84.180  1.00 164.13 ? 92  LEU B C   1 
ATOM   5028  O O   . LEU B 1 92  ? 84.859  99.729  84.573  1.00 163.64 ? 92  LEU B O   1 
ATOM   5029  C CB  . LEU B 1 92  ? 87.137  101.622 85.163  1.00 164.77 ? 92  LEU B CB  1 
ATOM   5030  C CG  . LEU B 1 92  ? 88.188  102.253 86.094  1.00 164.40 ? 92  LEU B CG  1 
ATOM   5031  C CD1 . LEU B 1 92  ? 88.224  103.771 85.923  1.00 164.36 ? 92  LEU B CD1 1 
ATOM   5032  C CD2 . LEU B 1 92  ? 87.868  101.959 87.559  1.00 162.78 ? 92  LEU B CD2 1 
ATOM   5033  N N   . THR B 1 93  ? 86.266  98.966  83.011  1.00 167.27 ? 93  THR B N   1 
ATOM   5034  C CA  . THR B 1 93  ? 85.218  98.501  82.080  1.00 168.41 ? 93  THR B CA  1 
ATOM   5035  C C   . THR B 1 93  ? 84.264  97.502  82.751  1.00 168.85 ? 93  THR B C   1 
ATOM   5036  O O   . THR B 1 93  ? 84.673  96.414  83.153  1.00 169.47 ? 93  THR B O   1 
ATOM   5037  C CB  . THR B 1 93  ? 85.834  97.886  80.813  1.00 166.69 ? 93  THR B CB  1 
ATOM   5038  O OG1 . THR B 1 93  ? 86.592  98.855  80.130  1.00 166.49 ? 93  THR B OG1 1 
ATOM   5039  C CG2 . THR B 1 93  ? 84.780  97.399  79.820  1.00 166.21 ? 93  THR B CG2 1 
ATOM   5040  N N   . GLY B 1 94  ? 82.985  97.868  82.869  1.00 170.30 ? 94  GLY B N   1 
ATOM   5041  C CA  . GLY B 1 94  ? 81.945  97.085  83.545  1.00 170.34 ? 94  GLY B CA  1 
ATOM   5042  C C   . GLY B 1 94  ? 81.580  97.550  84.963  1.00 171.12 ? 94  GLY B C   1 
ATOM   5043  O O   . GLY B 1 94  ? 80.576  97.087  85.508  1.00 170.58 ? 94  GLY B O   1 
ATOM   5044  N N   . LEU B 1 95  ? 82.317  98.501  85.552  1.00 170.01 ? 95  LEU B N   1 
ATOM   5045  C CA  . LEU B 1 95  ? 81.988  99.054  86.872  1.00 169.67 ? 95  LEU B CA  1 
ATOM   5046  C C   . LEU B 1 95  ? 80.607  99.735  86.885  1.00 169.52 ? 95  LEU B C   1 
ATOM   5047  O O   . LEU B 1 95  ? 79.853  99.576  87.842  1.00 169.80 ? 95  LEU B O   1 
ATOM   5048  C CB  . LEU B 1 95  ? 83.120  100.011 87.294  1.00 169.12 ? 95  LEU B CB  1 
ATOM   5049  C CG  . LEU B 1 95  ? 82.925  100.733 88.644  1.00 169.26 ? 95  LEU B CG  1 
ATOM   5050  C CD1 . LEU B 1 95  ? 82.778  99.772  89.818  1.00 168.56 ? 95  LEU B CD1 1 
ATOM   5051  C CD2 . LEU B 1 95  ? 84.150  101.600 88.923  1.00 168.56 ? 95  LEU B CD2 1 
ATOM   5052  N N   . LEU B 1 96  ? 80.237  100.422 85.792  1.00 168.90 ? 96  LEU B N   1 
ATOM   5053  C CA  . LEU B 1 96  ? 78.906  101.024 85.635  1.00 168.66 ? 96  LEU B CA  1 
ATOM   5054  C C   . LEU B 1 96  ? 77.798  99.974  85.773  1.00 169.90 ? 96  LEU B C   1 
ATOM   5055  O O   . LEU B 1 96  ? 76.835  100.164 86.513  1.00 169.49 ? 96  LEU B O   1 
ATOM   5056  C CB  . LEU B 1 96  ? 78.749  101.709 84.261  1.00 169.72 ? 96  LEU B CB  1 
ATOM   5057  C CG  . LEU B 1 96  ? 79.722  102.854 83.938  1.00 169.53 ? 96  LEU B CG  1 
ATOM   5058  C CD1 . LEU B 1 96  ? 81.017  102.347 83.293  1.00 169.28 ? 96  LEU B CD1 1 
ATOM   5059  C CD2 . LEU B 1 96  ? 79.072  103.826 82.958  1.00 168.05 ? 96  LEU B CD2 1 
ATOM   5060  N N   . GLU B 1 97  ? 77.930  98.850  85.065  1.00 172.75 ? 97  GLU B N   1 
ATOM   5061  C CA  . GLU B 1 97  ? 76.930  97.779  85.068  1.00 171.98 ? 97  GLU B CA  1 
ATOM   5062  C C   . GLU B 1 97  ? 76.794  97.141  86.452  1.00 172.68 ? 97  GLU B C   1 
ATOM   5063  O O   . GLU B 1 97  ? 75.677  96.921  86.913  1.00 170.83 ? 97  GLU B O   1 
ATOM   5064  C CB  . GLU B 1 97  ? 77.288  96.702  84.036  1.00 169.59 ? 97  GLU B CB  1 
ATOM   5065  N N   . TYR B 1 98  ? 77.907  96.892  87.148  1.00 173.59 ? 98  TYR B N   1 
ATOM   5066  C CA  . TYR B 1 98  ? 77.858  96.302  88.486  1.00 172.90 ? 98  TYR B CA  1 
ATOM   5067  C C   . TYR B 1 98  ? 77.201  97.237  89.510  1.00 173.08 ? 98  TYR B C   1 
ATOM   5068  O O   . TYR B 1 98  ? 76.336  96.800  90.272  1.00 173.24 ? 98  TYR B O   1 
ATOM   5069  C CB  . TYR B 1 98  ? 79.264  95.904  88.936  1.00 172.63 ? 98  TYR B CB  1 
ATOM   5070  C CG  . TYR B 1 98  ? 79.253  95.135  90.242  1.00 173.38 ? 98  TYR B CG  1 
ATOM   5071  C CD1 . TYR B 1 98  ? 78.860  93.782  90.249  1.00 172.92 ? 98  TYR B CD1 1 
ATOM   5072  C CD2 . TYR B 1 98  ? 79.597  95.768  91.451  1.00 172.51 ? 98  TYR B CD2 1 
ATOM   5073  C CE1 . TYR B 1 98  ? 78.845  93.054  91.456  1.00 172.88 ? 98  TYR B CE1 1 
ATOM   5074  C CE2 . TYR B 1 98  ? 79.579  95.046  92.659  1.00 172.91 ? 98  TYR B CE2 1 
ATOM   5075  C CZ  . TYR B 1 98  ? 79.218  93.681  92.662  1.00 173.61 ? 98  TYR B CZ  1 
ATOM   5076  O OH  . TYR B 1 98  ? 79.219  92.969  93.819  1.00 171.77 ? 98  TYR B OH  1 
ATOM   5077  N N   . LEU B 1 99  ? 77.559  98.525  89.512  1.00 172.99 ? 99  LEU B N   1 
ATOM   5078  C CA  . LEU B 1 99  ? 76.958  99.524  90.404  1.00 173.81 ? 99  LEU B CA  1 
ATOM   5079  C C   . LEU B 1 99  ? 75.450  99.658  90.156  1.00 173.47 ? 99  LEU B C   1 
ATOM   5080  O O   . LEU B 1 99  ? 74.661  99.575  91.098  1.00 172.04 ? 99  LEU B O   1 
ATOM   5081  C CB  . LEU B 1 99  ? 77.665  100.876 90.215  1.00 173.48 ? 99  LEU B CB  1 
ATOM   5082  C CG  . LEU B 1 99  ? 79.109  100.917 90.741  1.00 173.13 ? 99  LEU B CG  1 
ATOM   5083  C CD1 . LEU B 1 99  ? 79.765  102.217 90.286  1.00 172.85 ? 99  LEU B CD1 1 
ATOM   5084  C CD2 . LEU B 1 99  ? 79.181  100.841 92.265  1.00 170.64 ? 99  LEU B CD2 1 
ATOM   5085  N N   . ARG B 1 100 ? 75.030  99.781  88.890  1.00 175.73 ? 100 ARG B N   1 
ATOM   5086  C CA  . ARG B 1 100 ? 73.608  99.866  88.514  1.00 175.75 ? 100 ARG B CA  1 
ATOM   5087  C C   . ARG B 1 100 ? 72.826  98.595  88.852  1.00 175.90 ? 100 ARG B C   1 
ATOM   5088  O O   . ARG B 1 100 ? 71.730  98.691  89.401  1.00 175.95 ? 100 ARG B O   1 
ATOM   5089  C CB  . ARG B 1 100 ? 73.485  100.195 87.019  1.00 174.90 ? 100 ARG B CB  1 
ATOM   5090  C CG  . ARG B 1 100 ? 73.838  101.659 86.723  1.00 174.09 ? 100 ARG B CG  1 
ATOM   5091  C CD  . ARG B 1 100 ? 73.750  101.926 85.219  1.00 173.86 ? 100 ARG B CD  1 
ATOM   5092  N NE  . ARG B 1 100 ? 73.873  103.359 84.905  1.00 175.81 ? 100 ARG B NE  1 
ATOM   5093  C CZ  . ARG B 1 100 ? 73.741  103.916 83.717  1.00 175.45 ? 100 ARG B CZ  1 
ATOM   5094  N NH1 . ARG B 1 100 ? 73.829  105.203 83.590  1.00 174.36 ? 100 ARG B NH1 1 
ATOM   5095  N NH2 . ARG B 1 100 ? 73.526  103.219 82.641  1.00 174.77 ? 100 ARG B NH2 1 
ATOM   5096  N N   . TRP B 1 101 ? 73.380  97.412  88.585  1.00 177.48 ? 101 TRP B N   1 
ATOM   5097  C CA  . TRP B 1 101 ? 72.704  96.133  88.842  1.00 177.61 ? 101 TRP B CA  1 
ATOM   5098  C C   . TRP B 1 101 ? 72.507  95.861  90.342  1.00 177.80 ? 101 TRP B C   1 
ATOM   5099  O O   . TRP B 1 101 ? 71.452  95.382  90.752  1.00 176.21 ? 101 TRP B O   1 
ATOM   5100  C CB  . TRP B 1 101 ? 73.482  95.008  88.143  1.00 177.18 ? 101 TRP B CB  1 
ATOM   5101  C CG  . TRP B 1 101 ? 72.817  93.666  88.119  1.00 178.34 ? 101 TRP B CG  1 
ATOM   5102  C CD1 . TRP B 1 101 ? 72.031  93.213  87.115  1.00 177.28 ? 101 TRP B CD1 1 
ATOM   5103  C CD2 . TRP B 1 101 ? 72.828  92.600  89.121  1.00 179.09 ? 101 TRP B CD2 1 
ATOM   5104  N NE1 . TRP B 1 101 ? 71.566  91.950  87.417  1.00 177.77 ? 101 TRP B NE1 1 
ATOM   5105  C CE2 . TRP B 1 101 ? 72.021  91.523  88.644  1.00 179.18 ? 101 TRP B CE2 1 
ATOM   5106  C CE3 . TRP B 1 101 ? 73.432  92.428  90.384  1.00 177.55 ? 101 TRP B CE3 1 
ATOM   5107  C CZ2 . TRP B 1 101 ? 71.820  90.347  89.380  1.00 177.81 ? 101 TRP B CZ2 1 
ATOM   5108  C CZ3 . TRP B 1 101 ? 73.239  91.252  91.132  1.00 176.74 ? 101 TRP B CZ3 1 
ATOM   5109  C CH2 . TRP B 1 101 ? 72.435  90.211  90.634  1.00 177.01 ? 101 TRP B CH2 1 
ATOM   5110  N N   . ASN B 1 102 ? 73.478  96.235  91.182  1.00 177.50 ? 102 ASN B N   1 
ATOM   5111  C CA  . ASN B 1 102 ? 73.351  96.175  92.645  1.00 177.02 ? 102 ASN B CA  1 
ATOM   5112  C C   . ASN B 1 102 ? 72.596  97.383  93.251  1.00 177.42 ? 102 ASN B C   1 
ATOM   5113  O O   . ASN B 1 102 ? 72.213  97.333  94.418  1.00 177.32 ? 102 ASN B O   1 
ATOM   5114  C CB  . ASN B 1 102 ? 74.745  96.018  93.274  1.00 177.84 ? 102 ASN B CB  1 
ATOM   5115  C CG  . ASN B 1 102 ? 75.366  94.664  92.984  1.00 177.97 ? 102 ASN B CG  1 
ATOM   5116  O OD1 . ASN B 1 102 ? 75.157  93.696  93.699  1.00 176.83 ? 102 ASN B OD1 1 
ATOM   5117  N ND2 . ASN B 1 102 ? 76.149  94.556  91.942  1.00 177.69 ? 102 ASN B ND2 1 
ATOM   5118  N N   . SER B 1 103 ? 72.371  98.458  92.488  1.00 175.44 ? 103 SER B N   1 
ATOM   5119  C CA  . SER B 1 103 ? 71.842  99.768  92.925  1.00 175.40 ? 103 SER B CA  1 
ATOM   5120  C C   . SER B 1 103 ? 72.721  100.514 93.953  1.00 175.70 ? 103 SER B C   1 
ATOM   5121  O O   . SER B 1 103 ? 72.223  101.300 94.763  1.00 174.28 ? 103 SER B O   1 
ATOM   5122  C CB  . SER B 1 103 ? 70.356  99.674  93.315  1.00 174.43 ? 103 SER B CB  1 
ATOM   5123  O OG  . SER B 1 103 ? 70.161  99.023  94.558  1.00 175.43 ? 103 SER B OG  1 
ATOM   5124  N N   . LYS B 1 104 ? 74.039  100.268 93.936  1.00 171.66 ? 104 LYS B N   1 
ATOM   5125  C CA  . LYS B 1 104 ? 75.016  100.829 94.891  1.00 170.50 ? 104 LYS B CA  1 
ATOM   5126  C C   . LYS B 1 104 ? 75.790  102.016 94.312  1.00 171.29 ? 104 LYS B C   1 
ATOM   5127  O O   . LYS B 1 104 ? 75.817  102.218 93.100  1.00 170.39 ? 104 LYS B O   1 
ATOM   5128  C CB  . LYS B 1 104 ? 75.966  99.726  95.384  1.00 170.25 ? 104 LYS B CB  1 
ATOM   5129  C CG  . LYS B 1 104 ? 75.188  98.625  96.114  1.00 170.92 ? 104 LYS B CG  1 
ATOM   5130  C CD  . LYS B 1 104 ? 76.087  97.665  96.905  1.00 170.42 ? 104 LYS B CD  1 
ATOM   5131  C CE  . LYS B 1 104 ? 76.663  98.311  98.171  1.00 171.00 ? 104 LYS B CE  1 
ATOM   5132  N NZ  . LYS B 1 104 ? 75.613  98.597  99.180  1.00 170.60 ? 104 LYS B NZ  1 
ATOM   5133  N N   . TYR B 1 105 ? 76.450  102.776 95.188  1.00 164.08 ? 105 TYR B N   1 
ATOM   5134  C CA  . TYR B 1 105 ? 77.210  103.985 94.856  1.00 162.26 ? 105 TYR B CA  1 
ATOM   5135  C C   . TYR B 1 105 ? 78.656  103.919 95.374  1.00 161.39 ? 105 TYR B C   1 
ATOM   5136  O O   . TYR B 1 105 ? 78.908  103.373 96.447  1.00 160.84 ? 105 TYR B O   1 
ATOM   5137  C CB  . TYR B 1 105 ? 76.494  105.211 95.445  1.00 161.34 ? 105 TYR B CB  1 
ATOM   5138  C CG  . TYR B 1 105 ? 75.019  105.349 95.117  1.00 162.38 ? 105 TYR B CG  1 
ATOM   5139  C CD1 . TYR B 1 105 ? 74.606  105.601 93.796  1.00 162.22 ? 105 TYR B CD1 1 
ATOM   5140  C CD2 . TYR B 1 105 ? 74.059  105.256 96.143  1.00 161.17 ? 105 TYR B CD2 1 
ATOM   5141  C CE1 . TYR B 1 105 ? 73.240  105.779 93.506  1.00 161.96 ? 105 TYR B CE1 1 
ATOM   5142  C CE2 . TYR B 1 105 ? 72.692  105.419 95.852  1.00 161.84 ? 105 TYR B CE2 1 
ATOM   5143  C CZ  . TYR B 1 105 ? 72.280  105.691 94.533  1.00 162.09 ? 105 TYR B CZ  1 
ATOM   5144  O OH  . TYR B 1 105 ? 70.970  105.886 94.245  1.00 160.33 ? 105 TYR B OH  1 
ATOM   5145  N N   . LEU B 1 106 ? 79.601  104.555 94.675  1.00 150.03 ? 106 LEU B N   1 
ATOM   5146  C CA  . LEU B 1 106 ? 81.024  104.600 95.062  1.00 149.32 ? 106 LEU B CA  1 
ATOM   5147  C C   . LEU B 1 106 ? 81.302  105.326 96.395  1.00 151.31 ? 106 LEU B C   1 
ATOM   5148  O O   . LEU B 1 106 ? 82.402  105.218 96.934  1.00 150.36 ? 106 LEU B O   1 
ATOM   5149  C CB  . LEU B 1 106 ? 81.842  105.242 93.925  1.00 149.54 ? 106 LEU B CB  1 
ATOM   5150  C CG  . LEU B 1 106 ? 81.915  104.417 92.632  1.00 150.79 ? 106 LEU B CG  1 
ATOM   5151  C CD1 . LEU B 1 106 ? 82.702  105.191 91.579  1.00 149.77 ? 106 LEU B CD1 1 
ATOM   5152  C CD2 . LEU B 1 106 ? 82.611  103.081 92.866  1.00 152.39 ? 106 LEU B CD2 1 
ATOM   5153  N N   . THR B 1 107 ? 80.326  106.057 96.938  1.00 156.75 ? 107 THR B N   1 
ATOM   5154  C CA  . THR B 1 107 ? 80.400  106.712 98.261  1.00 155.38 ? 107 THR B CA  1 
ATOM   5155  C C   . THR B 1 107 ? 79.646  105.966 99.366  1.00 155.20 ? 107 THR B C   1 
ATOM   5156  O O   . THR B 1 107 ? 79.600  106.445 100.500 1.00 155.29 ? 107 THR B O   1 
ATOM   5157  C CB  . THR B 1 107 ? 79.954  108.182 98.195  1.00 154.37 ? 107 THR B CB  1 
ATOM   5158  O OG1 . THR B 1 107 ? 78.632  108.325 97.736  1.00 154.90 ? 107 THR B OG1 1 
ATOM   5159  C CG2 . THR B 1 107 ? 80.838  108.970 97.246  1.00 154.02 ? 107 THR B CG2 1 
ATOM   5160  N N   . ASP B 1 108 ? 79.072  104.789 99.090  1.00 155.88 ? 108 ASP B N   1 
ATOM   5161  C CA  . ASP B 1 108 ? 78.535  103.905 100.131 1.00 156.33 ? 108 ASP B CA  1 
ATOM   5162  C C   . ASP B 1 108 ? 79.667  103.185 100.891 1.00 156.00 ? 108 ASP B C   1 
ATOM   5163  O O   . ASP B 1 108 ? 80.744  102.951 100.342 1.00 155.96 ? 108 ASP B O   1 
ATOM   5164  C CB  . ASP B 1 108 ? 77.555  102.896 99.512  1.00 156.90 ? 108 ASP B CB  1 
ATOM   5165  C CG  . ASP B 1 108 ? 76.736  102.140 100.566 1.00 157.28 ? 108 ASP B CG  1 
ATOM   5166  O OD1 . ASP B 1 108 ? 76.588  102.648 101.697 1.00 156.00 ? 108 ASP B OD1 1 
ATOM   5167  O OD2 . ASP B 1 108 ? 76.254  101.028 100.264 1.00 157.10 ? 108 ASP B OD2 1 
ATOM   5168  N N   . SER B 1 109 ? 79.428  102.779 102.142 1.00 151.54 ? 109 SER B N   1 
ATOM   5169  C CA  . SER B 1 109 ? 80.444  102.196 103.043 1.00 152.67 ? 109 SER B CA  1 
ATOM   5170  C C   . SER B 1 109 ? 81.224  101.026 102.422 1.00 153.60 ? 109 SER B C   1 
ATOM   5171  O O   . SER B 1 109 ? 82.441  100.929 102.591 1.00 152.91 ? 109 SER B O   1 
ATOM   5172  C CB  . SER B 1 109 ? 79.758  101.744 104.338 1.00 151.35 ? 109 SER B CB  1 
ATOM   5173  O OG  . SER B 1 109 ? 80.682  101.168 105.238 1.00 150.29 ? 109 SER B OG  1 
ATOM   5174  N N   . ALA B 1 110 ? 80.557  100.202 101.610 1.00 152.06 ? 110 ALA B N   1 
ATOM   5175  C CA  . ALA B 1 110 ? 81.152  99.069  100.902 1.00 150.46 ? 110 ALA B CA  1 
ATOM   5176  C C   . ALA B 1 110 ? 82.357  99.427  100.005 1.00 151.80 ? 110 ALA B C   1 
ATOM   5177  O O   . ALA B 1 110 ? 83.172  98.551  99.737  1.00 152.76 ? 110 ALA B O   1 
ATOM   5178  C CB  . ALA B 1 110 ? 80.043  98.408  100.077 1.00 149.74 ? 110 ALA B CB  1 
ATOM   5179  N N   . TYR B 1 111 ? 82.505  100.685 99.574  1.00 152.16 ? 111 TYR B N   1 
ATOM   5180  C CA  . TYR B 1 111 ? 83.607  101.178 98.735  1.00 151.30 ? 111 TYR B CA  1 
ATOM   5181  C C   . TYR B 1 111 ? 84.593  102.089 99.491  1.00 150.40 ? 111 TYR B C   1 
ATOM   5182  O O   . TYR B 1 111 ? 85.262  102.923 98.887  1.00 150.07 ? 111 TYR B O   1 
ATOM   5183  C CB  . TYR B 1 111 ? 83.029  101.823 97.466  1.00 152.43 ? 111 TYR B CB  1 
ATOM   5184  C CG  . TYR B 1 111 ? 82.476  100.823 96.471  1.00 151.55 ? 111 TYR B CG  1 
ATOM   5185  C CD1 . TYR B 1 111 ? 83.340  100.251 95.519  1.00 150.52 ? 111 TYR B CD1 1 
ATOM   5186  C CD2 . TYR B 1 111 ? 81.119  100.460 96.495  1.00 151.87 ? 111 TYR B CD2 1 
ATOM   5187  C CE1 . TYR B 1 111 ? 82.851  99.315  94.591  1.00 152.32 ? 111 TYR B CE1 1 
ATOM   5188  C CE2 . TYR B 1 111 ? 80.632  99.509  95.581  1.00 151.83 ? 111 TYR B CE2 1 
ATOM   5189  C CZ  . TYR B 1 111 ? 81.497  98.934  94.630  1.00 153.69 ? 111 TYR B CZ  1 
ATOM   5190  O OH  . TYR B 1 111 ? 81.026  97.999  93.764  1.00 155.97 ? 111 TYR B OH  1 
ATOM   5191  N N   . THR B 1 112 ? 84.718  101.939 100.813 1.00 144.04 ? 112 THR B N   1 
ATOM   5192  C CA  . THR B 1 112 ? 85.595  102.770 101.656 1.00 145.72 ? 112 THR B CA  1 
ATOM   5193  C C   . THR B 1 112 ? 86.663  101.959 102.396 1.00 145.60 ? 112 THR B C   1 
ATOM   5194  O O   . THR B 1 112 ? 86.456  100.790 102.730 1.00 147.17 ? 112 THR B O   1 
ATOM   5195  C CB  . THR B 1 112 ? 84.791  103.629 102.641 1.00 146.74 ? 112 THR B CB  1 
ATOM   5196  O OG1 . THR B 1 112 ? 84.119  102.844 103.595 1.00 145.16 ? 112 THR B OG1 1 
ATOM   5197  C CG2 . THR B 1 112 ? 83.758  104.506 101.942 1.00 145.06 ? 112 THR B CG2 1 
ATOM   5198  N N   . GLU B 1 113 ? 87.841  102.552 102.624 1.00 141.01 ? 113 GLU B N   1 
ATOM   5199  C CA  . GLU B 1 113 ? 88.924  101.921 103.390 1.00 141.78 ? 113 GLU B CA  1 
ATOM   5200  C C   . GLU B 1 113 ? 88.554  101.751 104.878 1.00 142.07 ? 113 GLU B C   1 
ATOM   5201  O O   . GLU B 1 113 ? 87.739  102.495 105.426 1.00 140.63 ? 113 GLU B O   1 
ATOM   5202  C CB  . GLU B 1 113 ? 90.249  102.689 103.208 1.00 141.77 ? 113 GLU B CB  1 
ATOM   5203  C CG  . GLU B 1 113 ? 91.463  101.769 103.223 1.00 140.76 ? 113 GLU B CG  1 
ATOM   5204  C CD  . GLU B 1 113 ? 92.741  102.411 102.671 1.00 142.75 ? 113 GLU B CD  1 
ATOM   5205  O OE1 . GLU B 1 113 ? 93.283  103.340 103.296 1.00 142.30 ? 113 GLU B OE1 1 
ATOM   5206  O OE2 . GLU B 1 113 ? 93.231  101.979 101.612 1.00 143.85 ? 113 GLU B OE2 1 
ATOM   5207  N N   . GLY B 1 114 ? 89.132  100.751 105.548 1.00 142.83 ? 114 GLY B N   1 
ATOM   5208  C CA  . GLY B 1 114 ? 88.771  100.380 106.919 1.00 141.81 ? 114 GLY B CA  1 
ATOM   5209  C C   . GLY B 1 114 ? 89.108  101.436 107.976 1.00 143.13 ? 114 GLY B C   1 
ATOM   5210  O O   . GLY B 1 114 ? 90.129  102.120 107.890 1.00 142.31 ? 114 GLY B O   1 
ATOM   5211  N N   . SER B 1 115 ? 88.263  101.542 109.006 1.00 140.99 ? 115 SER B N   1 
ATOM   5212  C CA  . SER B 1 115 ? 88.395  102.474 110.145 1.00 139.73 ? 115 SER B CA  1 
ATOM   5213  C C   . SER B 1 115 ? 88.427  103.965 109.766 1.00 139.27 ? 115 SER B C   1 
ATOM   5214  O O   . SER B 1 115 ? 88.919  104.797 110.525 1.00 137.08 ? 115 SER B O   1 
ATOM   5215  C CB  . SER B 1 115 ? 89.566  102.086 111.062 1.00 138.79 ? 115 SER B CB  1 
ATOM   5216  O OG  . SER B 1 115 ? 89.434  100.743 111.491 1.00 138.05 ? 115 SER B OG  1 
ATOM   5217  N N   . THR B 1 116 ? 87.894  104.320 108.596 1.00 138.40 ? 116 THR B N   1 
ATOM   5218  C CA  . THR B 1 116 ? 87.793  105.695 108.077 1.00 137.46 ? 116 THR B CA  1 
ATOM   5219  C C   . THR B 1 116 ? 86.638  105.799 107.056 1.00 134.93 ? 116 THR B C   1 
ATOM   5220  O O   . THR B 1 116 ? 85.798  104.905 106.985 1.00 136.12 ? 116 THR B O   1 
ATOM   5221  C CB  . THR B 1 116 ? 89.164  106.142 107.525 1.00 134.07 ? 116 THR B CB  1 
ATOM   5222  O OG1 . THR B 1 116 ? 89.129  107.496 107.158 1.00 131.58 ? 116 THR B OG1 1 
ATOM   5223  C CG2 . THR B 1 116 ? 89.646  105.354 106.309 1.00 132.40 ? 116 THR B CG2 1 
ATOM   5224  N N   . GLY B 1 117 ? 86.561  106.877 106.271 1.00 121.64 ? 117 GLY B N   1 
ATOM   5225  C CA  . GLY B 1 117 ? 85.593  107.057 105.174 1.00 124.46 ? 117 GLY B CA  1 
ATOM   5226  C C   . GLY B 1 117 ? 86.231  107.140 103.781 1.00 124.93 ? 117 GLY B C   1 
ATOM   5227  O O   . GLY B 1 117 ? 85.556  107.437 102.801 1.00 125.66 ? 117 GLY B O   1 
ATOM   5228  N N   . LYS B 1 118 ? 87.545  106.921 103.702 1.00 121.52 ? 118 LYS B N   1 
ATOM   5229  C CA  . LYS B 1 118 ? 88.411  107.155 102.541 1.00 121.91 ? 118 LYS B CA  1 
ATOM   5230  C C   . LYS B 1 118 ? 87.945  106.391 101.302 1.00 120.73 ? 118 LYS B C   1 
ATOM   5231  O O   . LYS B 1 118 ? 87.837  105.169 101.343 1.00 125.48 ? 118 LYS B O   1 
ATOM   5232  C CB  . LYS B 1 118 ? 89.815  106.755 102.994 1.00 122.47 ? 118 LYS B CB  1 
ATOM   5233  C CG  . LYS B 1 118 ? 90.952  106.943 101.988 1.00 121.32 ? 118 LYS B CG  1 
ATOM   5234  C CD  . LYS B 1 118 ? 92.237  106.571 102.736 1.00 123.93 ? 118 LYS B CD  1 
ATOM   5235  C CE  . LYS B 1 118 ? 93.462  106.426 101.841 1.00 123.38 ? 118 LYS B CE  1 
ATOM   5236  N NZ  . LYS B 1 118 ? 94.549  105.740 102.581 1.00 125.35 ? 118 LYS B NZ  1 
ATOM   5237  N N   . THR B 1 119 ? 87.647  107.105 100.221 1.00 126.50 ? 119 THR B N   1 
ATOM   5238  C CA  . THR B 1 119 ? 87.024  106.562 99.001  1.00 129.18 ? 119 THR B CA  1 
ATOM   5239  C C   . THR B 1 119 ? 88.038  106.169 97.930  1.00 127.83 ? 119 THR B C   1 
ATOM   5240  O O   . THR B 1 119 ? 89.217  106.524 97.992  1.00 126.85 ? 119 THR B O   1 
ATOM   5241  C CB  . THR B 1 119 ? 86.019  107.559 98.398  1.00 131.26 ? 119 THR B CB  1 
ATOM   5242  O OG1 . THR B 1 119 ? 86.691  108.700 97.916  1.00 130.67 ? 119 THR B OG1 1 
ATOM   5243  C CG2 . THR B 1 119 ? 84.946  108.019 99.378  1.00 129.15 ? 119 THR B CG2 1 
ATOM   5244  N N   . CYS B 1 120 ? 87.563  105.503 96.882  1.00 131.76 ? 120 CYS B N   1 
ATOM   5245  C CA  . CYS B 1 120 ? 88.328  105.210 95.666  1.00 133.51 ? 120 CYS B CA  1 
ATOM   5246  C C   . CYS B 1 120 ? 88.929  106.454 94.997  1.00 135.32 ? 120 CYS B C   1 
ATOM   5247  O O   . CYS B 1 120 ? 90.035  106.380 94.471  1.00 134.36 ? 120 CYS B O   1 
ATOM   5248  C CB  . CYS B 1 120 ? 87.408  104.467 94.684  1.00 134.14 ? 120 CYS B CB  1 
ATOM   5249  S SG  . CYS B 1 120 ? 85.860  105.378 94.441  1.00 135.11 ? 120 CYS B SG  1 
ATOM   5250  N N   . LEU B 1 121 ? 88.269  107.616 95.051  1.00 128.91 ? 121 LEU B N   1 
ATOM   5251  C CA  . LEU B 1 121 ? 88.829  108.861 94.520  1.00 127.17 ? 121 LEU B CA  1 
ATOM   5252  C C   . LEU B 1 121 ? 90.041  109.329 95.339  1.00 127.63 ? 121 LEU B C   1 
ATOM   5253  O O   . LEU B 1 121 ? 91.037  109.757 94.766  1.00 130.87 ? 121 LEU B O   1 
ATOM   5254  C CB  . LEU B 1 121 ? 87.726  109.927 94.439  1.00 125.63 ? 121 LEU B CB  1 
ATOM   5255  C CG  . LEU B 1 121 ? 88.185  111.269 93.840  1.00 125.39 ? 121 LEU B CG  1 
ATOM   5256  C CD1 . LEU B 1 121 ? 88.486  111.158 92.350  1.00 126.27 ? 121 LEU B CD1 1 
ATOM   5257  C CD2 . LEU B 1 121 ? 87.097  112.320 94.024  1.00 125.94 ? 121 LEU B CD2 1 
ATOM   5258  N N   . MET B 1 122 ? 90.012  109.206 96.663  1.00 114.28 ? 122 MET B N   1 
ATOM   5259  C CA  . MET B 1 122 ? 91.191  109.506 97.476  1.00 114.83 ? 122 MET B CA  1 
ATOM   5260  C C   . MET B 1 122 ? 92.342  108.539 97.150  1.00 117.83 ? 122 MET B C   1 
ATOM   5261  O O   . MET B 1 122 ? 93.471  108.975 96.940  1.00 114.54 ? 122 MET B O   1 
ATOM   5262  C CB  . MET B 1 122 ? 90.802  109.483 98.957  1.00 116.99 ? 122 MET B CB  1 
ATOM   5263  C CG  . MET B 1 122 ? 89.721  110.522 99.253  1.00 112.92 ? 122 MET B CG  1 
ATOM   5264  S SD  . MET B 1 122 ? 89.200  110.566 100.974 1.00 113.27 ? 122 MET B SD  1 
ATOM   5265  C CE  . MET B 1 122 ? 87.536  111.225 100.760 1.00 113.37 ? 122 MET B CE  1 
ATOM   5266  N N   . LYS B 1 123 ? 92.054  107.238 96.996  1.00 129.75 ? 123 LYS B N   1 
ATOM   5267  C CA  . LYS B 1 123 ? 93.011  106.210 96.550  1.00 128.03 ? 123 LYS B CA  1 
ATOM   5268  C C   . LYS B 1 123 ? 93.622  106.527 95.174  1.00 128.17 ? 123 LYS B C   1 
ATOM   5269  O O   . LYS B 1 123 ? 94.815  106.322 94.977  1.00 128.74 ? 123 LYS B O   1 
ATOM   5270  C CB  . LYS B 1 123 ? 92.300  104.843 96.560  1.00 127.22 ? 123 LYS B CB  1 
ATOM   5271  C CG  . LYS B 1 123 ? 93.236  103.633 96.609  1.00 130.13 ? 123 LYS B CG  1 
ATOM   5272  C CD  . LYS B 1 123 ? 93.892  103.442 97.976  1.00 129.01 ? 123 LYS B CD  1 
ATOM   5273  C CE  . LYS B 1 123 ? 94.698  102.148 98.008  1.00 129.46 ? 123 LYS B CE  1 
ATOM   5274  N NZ  . LYS B 1 123 ? 95.302  101.912 99.335  1.00 128.58 ? 123 LYS B NZ  1 
ATOM   5275  N N   . ALA B 1 124 ? 92.830  107.086 94.253  1.00 121.64 ? 124 ALA B N   1 
ATOM   5276  C CA  . ALA B 1 124 ? 93.278  107.550 92.941  1.00 120.87 ? 124 ALA B CA  1 
ATOM   5277  C C   . ALA B 1 124 ? 94.194  108.781 93.030  1.00 121.28 ? 124 ALA B C   1 
ATOM   5278  O O   . ALA B 1 124 ? 95.272  108.792 92.438  1.00 121.76 ? 124 ALA B O   1 
ATOM   5279  C CB  . ALA B 1 124 ? 92.046  107.851 92.078  1.00 118.81 ? 124 ALA B CB  1 
ATOM   5280  N N   . VAL B 1 125 ? 93.798  109.809 93.786  1.00 117.51 ? 125 VAL B N   1 
ATOM   5281  C CA  . VAL B 1 125 ? 94.558  111.066 93.927  1.00 115.15 ? 125 VAL B CA  1 
ATOM   5282  C C   . VAL B 1 125 ? 95.842  110.894 94.757  1.00 114.04 ? 125 VAL B C   1 
ATOM   5283  O O   . VAL B 1 125 ? 96.807  111.611 94.535  1.00 112.31 ? 125 VAL B O   1 
ATOM   5284  C CB  . VAL B 1 125 ? 93.653  112.181 94.491  1.00 112.88 ? 125 VAL B CB  1 
ATOM   5285  C CG1 . VAL B 1 125 ? 94.386  113.510 94.670  1.00 112.10 ? 125 VAL B CG1 1 
ATOM   5286  C CG2 . VAL B 1 125 ? 92.491  112.494 93.541  1.00 113.46 ? 125 VAL B CG2 1 
ATOM   5287  N N   . LEU B 1 126 ? 95.928  109.909 95.655  1.00 110.74 ? 126 LEU B N   1 
ATOM   5288  C CA  . LEU B 1 126 ? 97.186  109.541 96.322  1.00 109.87 ? 126 LEU B CA  1 
ATOM   5289  C C   . LEU B 1 126 ? 98.241  108.922 95.377  1.00 110.14 ? 126 LEU B C   1 
ATOM   5290  O O   . LEU B 1 126 ? 99.409  108.832 95.743  1.00 107.98 ? 126 LEU B O   1 
ATOM   5291  C CB  . LEU B 1 126 ? 96.865  108.583 97.486  1.00 105.33 ? 126 LEU B CB  1 
ATOM   5292  C CG  . LEU B 1 126 ? 96.208  109.274 98.688  1.00 106.27 ? 126 LEU B CG  1 
ATOM   5293  C CD1 . LEU B 1 126 ? 95.522  108.266 99.600  1.00 107.53 ? 126 LEU B CD1 1 
ATOM   5294  C CD2 . LEU B 1 126 ? 97.236  110.032 99.521  1.00 107.33 ? 126 LEU B CD2 1 
ATOM   5295  N N   . ASN B 1 127 ? 97.852  108.500 94.170  1.00 124.50 ? 127 ASN B N   1 
ATOM   5296  C CA  . ASN B 1 127 ? 98.674  107.750 93.214  1.00 123.54 ? 127 ASN B CA  1 
ATOM   5297  C C   . ASN B 1 127 ? 98.829  108.485 91.866  1.00 125.55 ? 127 ASN B C   1 
ATOM   5298  O O   . ASN B 1 127 ? 98.731  107.886 90.799  1.00 123.84 ? 127 ASN B O   1 
ATOM   5299  C CB  . ASN B 1 127 ? 98.114  106.321 93.099  1.00 123.17 ? 127 ASN B CB  1 
ATOM   5300  C CG  . ASN B 1 127 ? 98.402  105.504 94.343  1.00 125.85 ? 127 ASN B CG  1 
ATOM   5301  O OD1 . ASN B 1 127 ? 99.525  105.090 94.586  1.00 124.45 ? 127 ASN B OD1 1 
ATOM   5302  N ND2 . ASN B 1 127 ? 97.426  105.238 95.171  1.00 124.09 ? 127 ASN B ND2 1 
ATOM   5303  N N   . LEU B 1 128 ? 99.082  109.800 91.883  1.00 132.52 ? 128 LEU B N   1 
ATOM   5304  C CA  . LEU B 1 128 ? 99.379  110.573 90.666  1.00 132.24 ? 128 LEU B CA  1 
ATOM   5305  C C   . LEU B 1 128 ? 100.713 110.140 90.036  1.00 131.85 ? 128 LEU B C   1 
ATOM   5306  O O   . LEU B 1 128 ? 101.691 109.891 90.739  1.00 128.96 ? 128 LEU B O   1 
ATOM   5307  C CB  . LEU B 1 128 ? 99.416  112.089 90.940  1.00 130.45 ? 128 LEU B CB  1 
ATOM   5308  C CG  . LEU B 1 128 ? 98.194  112.692 91.643  1.00 130.22 ? 128 LEU B CG  1 
ATOM   5309  C CD1 . LEU B 1 128 ? 98.318  114.206 91.694  1.00 130.25 ? 128 LEU B CD1 1 
ATOM   5310  C CD2 . LEU B 1 128 ? 96.875  112.357 90.957  1.00 129.16 ? 128 LEU B CD2 1 
ATOM   5311  N N   . GLN B 1 129 ? 100.768 110.094 88.708  1.00 141.99 ? 129 GLN B N   1 
ATOM   5312  C CA  . GLN B 1 129 ? 101.950 109.743 87.917  1.00 141.88 ? 129 GLN B CA  1 
ATOM   5313  C C   . GLN B 1 129 ? 102.342 110.952 87.062  1.00 140.30 ? 129 GLN B C   1 
ATOM   5314  O O   . GLN B 1 129 ? 101.537 111.449 86.277  1.00 138.60 ? 129 GLN B O   1 
ATOM   5315  C CB  . GLN B 1 129 ? 101.634 108.503 87.061  1.00 139.52 ? 129 GLN B CB  1 
ATOM   5316  C CG  . GLN B 1 129 ? 101.327 107.260 87.920  1.00 138.05 ? 129 GLN B CG  1 
ATOM   5317  C CD  . GLN B 1 129 ? 100.737 106.088 87.137  1.00 138.72 ? 129 GLN B CD  1 
ATOM   5318  O OE1 . GLN B 1 129 ? 100.508 106.130 85.938  1.00 139.49 ? 129 GLN B OE1 1 
ATOM   5319  N NE2 . GLN B 1 129 ? 100.458 104.986 87.794  1.00 139.78 ? 129 GLN B NE2 1 
ATOM   5320  N N   . ASP B 1 130 ? 103.557 111.479 87.234  1.00 137.80 ? 130 ASP B N   1 
ATOM   5321  C CA  . ASP B 1 130 ? 104.001 112.703 86.551  1.00 138.01 ? 130 ASP B CA  1 
ATOM   5322  C C   . ASP B 1 130 ? 103.044 113.907 86.713  1.00 138.26 ? 130 ASP B C   1 
ATOM   5323  O O   . ASP B 1 130 ? 102.928 114.751 85.829  1.00 137.58 ? 130 ASP B O   1 
ATOM   5324  C CB  . ASP B 1 130 ? 104.301 112.388 85.084  1.00 136.25 ? 130 ASP B CB  1 
ATOM   5325  N N   . GLY B 1 131 ? 102.338 113.981 87.849  1.00 135.36 ? 131 GLY B N   1 
ATOM   5326  C CA  . GLY B 1 131 ? 101.389 115.048 88.191  1.00 135.09 ? 131 GLY B CA  1 
ATOM   5327  C C   . GLY B 1 131 ? 99.905  114.778 87.907  1.00 135.03 ? 131 GLY B C   1 
ATOM   5328  O O   . GLY B 1 131 ? 99.087  115.620 88.273  1.00 135.96 ? 131 GLY B O   1 
ATOM   5329  N N   . VAL B 1 132 ? 99.518  113.644 87.303  1.00 137.66 ? 132 VAL B N   1 
ATOM   5330  C CA  . VAL B 1 132 ? 98.102  113.308 86.998  1.00 139.14 ? 132 VAL B CA  1 
ATOM   5331  C C   . VAL B 1 132 ? 97.807  111.799 87.095  1.00 138.94 ? 132 VAL B C   1 
ATOM   5332  O O   . VAL B 1 132 ? 98.696  110.977 86.914  1.00 135.51 ? 132 VAL B O   1 
ATOM   5333  C CB  . VAL B 1 132 ? 97.717  113.889 85.620  1.00 137.58 ? 132 VAL B CB  1 
ATOM   5334  C CG1 . VAL B 1 132 ? 98.402  113.187 84.446  1.00 136.89 ? 132 VAL B CG1 1 
ATOM   5335  C CG2 . VAL B 1 132 ? 96.207  113.869 85.374  1.00 134.85 ? 132 VAL B CG2 1 
ATOM   5336  N N   . ASN B 1 133 ? 96.566  111.400 87.394  1.00 140.41 ? 133 ASN B N   1 
ATOM   5337  C CA  . ASN B 1 133 ? 96.105  110.007 87.286  1.00 139.62 ? 133 ASN B CA  1 
ATOM   5338  C C   . ASN B 1 133 ? 94.983  109.910 86.239  1.00 140.53 ? 133 ASN B C   1 
ATOM   5339  O O   . ASN B 1 133 ? 93.923  110.516 86.397  1.00 139.82 ? 133 ASN B O   1 
ATOM   5340  C CB  . ASN B 1 133 ? 95.685  109.497 88.679  1.00 139.92 ? 133 ASN B CB  1 
ATOM   5341  C CG  . ASN B 1 133 ? 95.227  108.045 88.711  1.00 140.80 ? 133 ASN B CG  1 
ATOM   5342  O OD1 . ASN B 1 133 ? 94.847  107.461 87.709  1.00 139.21 ? 133 ASN B OD1 1 
ATOM   5343  N ND2 . ASN B 1 133 ? 95.238  107.420 89.862  1.00 141.10 ? 133 ASN B ND2 1 
ATOM   5344  N N   . ALA B 1 134 ? 95.189  109.119 85.185  1.00 146.12 ? 134 ALA B N   1 
ATOM   5345  C CA  . ALA B 1 134 ? 94.241  108.980 84.079  1.00 145.08 ? 134 ALA B CA  1 
ATOM   5346  C C   . ALA B 1 134 ? 92.887  108.350 84.472  1.00 146.79 ? 134 ALA B C   1 
ATOM   5347  O O   . ALA B 1 134 ? 91.919  108.483 83.726  1.00 147.41 ? 134 ALA B O   1 
ATOM   5348  C CB  . ALA B 1 134 ? 94.929  108.175 82.970  1.00 145.31 ? 134 ALA B CB  1 
ATOM   5349  N N   . CYS B 1 135 ? 92.788  107.686 85.629  1.00 147.40 ? 135 CYS B N   1 
ATOM   5350  C CA  . CYS B 1 135 ? 91.541  107.089 86.110  1.00 147.28 ? 135 CYS B CA  1 
ATOM   5351  C C   . CYS B 1 135 ? 90.533  108.110 86.654  1.00 147.73 ? 135 CYS B C   1 
ATOM   5352  O O   . CYS B 1 135 ? 89.349  107.795 86.707  1.00 146.85 ? 135 CYS B O   1 
ATOM   5353  C CB  . CYS B 1 135 ? 91.842  106.050 87.198  1.00 148.22 ? 135 CYS B CB  1 
ATOM   5354  S SG  . CYS B 1 135 ? 92.989  104.797 86.580  1.00 153.08 ? 135 CYS B SG  1 
ATOM   5355  N N   . ILE B 1 136 ? 90.953  109.309 87.074  1.00 143.94 ? 136 ILE B N   1 
ATOM   5356  C CA  . ILE B 1 136 ? 90.064  110.252 87.781  1.00 142.28 ? 136 ILE B CA  1 
ATOM   5357  C C   . ILE B 1 136 ? 88.899  110.704 86.892  1.00 141.35 ? 136 ILE B C   1 
ATOM   5358  O O   . ILE B 1 136 ? 87.748  110.611 87.302  1.00 142.51 ? 136 ILE B O   1 
ATOM   5359  C CB  . ILE B 1 136 ? 90.856  111.452 88.346  1.00 142.23 ? 136 ILE B CB  1 
ATOM   5360  C CG1 . ILE B 1 136 ? 91.827  110.987 89.451  1.00 141.43 ? 136 ILE B CG1 1 
ATOM   5361  C CG2 . ILE B 1 136 ? 89.904  112.521 88.911  1.00 143.53 ? 136 ILE B CG2 1 
ATOM   5362  C CD1 . ILE B 1 136 ? 92.893  112.033 89.778  1.00 138.36 ? 136 ILE B CD1 1 
ATOM   5363  N N   . MET B 1 137 ? 89.168  111.140 85.658  1.00 146.40 ? 137 MET B N   1 
ATOM   5364  C CA  . MET B 1 137 ? 88.122  111.580 84.730  1.00 147.62 ? 137 MET B CA  1 
ATOM   5365  C C   . MET B 1 137 ? 87.052  110.487 84.468  1.00 147.80 ? 137 MET B C   1 
ATOM   5366  O O   . MET B 1 137 ? 85.874  110.760 84.698  1.00 146.53 ? 137 MET B O   1 
ATOM   5367  C CB  . MET B 1 137 ? 88.772  112.148 83.458  1.00 145.69 ? 137 MET B CB  1 
ATOM   5368  C CG  . MET B 1 137 ? 87.788  112.745 82.447  1.00 146.93 ? 137 MET B CG  1 
ATOM   5369  S SD  . MET B 1 137 ? 87.103  114.369 82.883  1.00 148.85 ? 137 MET B SD  1 
ATOM   5370  C CE  . MET B 1 137 ? 85.498  113.899 83.565  1.00 145.66 ? 137 MET B CE  1 
ATOM   5371  N N   . PRO B 1 138 ? 87.392  109.241 84.075  1.00 149.59 ? 138 PRO B N   1 
ATOM   5372  C CA  . PRO B 1 138 ? 86.390  108.189 83.935  1.00 148.21 ? 138 PRO B CA  1 
ATOM   5373  C C   . PRO B 1 138 ? 85.771  107.752 85.272  1.00 148.44 ? 138 PRO B C   1 
ATOM   5374  O O   . PRO B 1 138 ? 84.574  107.500 85.294  1.00 149.82 ? 138 PRO B O   1 
ATOM   5375  C CB  . PRO B 1 138 ? 87.075  107.038 83.196  1.00 147.27 ? 138 PRO B CB  1 
ATOM   5376  C CG  . PRO B 1 138 ? 88.559  107.262 83.449  1.00 148.03 ? 138 PRO B CG  1 
ATOM   5377  C CD  . PRO B 1 138 ? 88.676  108.777 83.573  1.00 148.93 ? 138 PRO B CD  1 
ATOM   5378  N N   . LEU B 1 139 ? 86.500  107.718 86.393  1.00 142.98 ? 139 LEU B N   1 
ATOM   5379  C CA  . LEU B 1 139 ? 85.915  107.393 87.705  1.00 143.79 ? 139 LEU B CA  1 
ATOM   5380  C C   . LEU B 1 139 ? 84.822  108.402 88.105  1.00 145.49 ? 139 LEU B C   1 
ATOM   5381  O O   . LEU B 1 139 ? 83.751  108.019 88.577  1.00 144.35 ? 139 LEU B O   1 
ATOM   5382  C CB  . LEU B 1 139 ? 87.044  107.334 88.751  1.00 145.17 ? 139 LEU B CB  1 
ATOM   5383  C CG  . LEU B 1 139 ? 86.601  106.923 90.162  1.00 144.61 ? 139 LEU B CG  1 
ATOM   5384  C CD1 . LEU B 1 139 ? 86.238  105.441 90.222  1.00 145.06 ? 139 LEU B CD1 1 
ATOM   5385  C CD2 . LEU B 1 139 ? 87.735  107.180 91.150  1.00 143.86 ? 139 LEU B CD2 1 
ATOM   5386  N N   . LEU B 1 140 ? 85.058  109.693 87.862  1.00 144.75 ? 140 LEU B N   1 
ATOM   5387  C CA  . LEU B 1 140 ? 84.066  110.742 88.078  1.00 143.51 ? 140 LEU B CA  1 
ATOM   5388  C C   . LEU B 1 140 ? 82.888  110.645 87.101  1.00 142.89 ? 140 LEU B C   1 
ATOM   5389  O O   . LEU B 1 140 ? 81.746  110.802 87.524  1.00 141.53 ? 140 LEU B O   1 
ATOM   5390  C CB  . LEU B 1 140 ? 84.752  112.118 88.025  1.00 142.77 ? 140 LEU B CB  1 
ATOM   5391  C CG  . LEU B 1 140 ? 85.717  112.379 89.194  1.00 141.61 ? 140 LEU B CG  1 
ATOM   5392  C CD1 . LEU B 1 140 ? 86.339  113.766 89.059  1.00 140.75 ? 140 LEU B CD1 1 
ATOM   5393  C CD2 . LEU B 1 140 ? 85.003  112.305 90.538  1.00 140.49 ? 140 LEU B CD2 1 
ATOM   5394  N N   . GLN B 1 141 ? 83.138  110.250 85.860  1.00 150.71 ? 141 GLN B N   1 
ATOM   5395  C CA  . GLN B 1 141 ? 81.956  110.027 84.993  1.00 150.64 ? 141 GLN B CA  1 
ATOM   5396  C C   . GLN B 1 141 ? 81.168  108.853 85.582  1.00 149.63 ? 141 GLN B C   1 
ATOM   5397  O O   . GLN B 1 141 ? 79.950  109.004 85.775  1.00 148.30 ? 141 GLN B O   1 
ATOM   5398  C CB  . GLN B 1 141 ? 82.354  109.742 83.549  1.00 149.54 ? 141 GLN B CB  1 
ATOM   5399  C CG  . GLN B 1 141 ? 81.181  109.864 82.588  1.00 149.72 ? 141 GLN B CG  1 
ATOM   5400  C CD  . GLN B 1 141 ? 80.240  110.970 82.999  1.00 150.41 ? 141 GLN B CD  1 
ATOM   5401  O OE1 . GLN B 1 141 ? 80.467  112.142 82.709  1.00 149.60 ? 141 GLN B OE1 1 
ATOM   5402  N NE2 . GLN B 1 141 ? 79.169  110.605 83.683  1.00 150.90 ? 141 GLN B NE2 1 
ATOM   5403  N N   . ILE B 1 142 ? 81.845  107.741 85.881  1.00 153.00 ? 142 ILE B N   1 
ATOM   5404  C CA  . ILE B 1 142 ? 81.163  106.543 86.391  1.00 152.98 ? 142 ILE B CA  1 
ATOM   5405  C C   . ILE B 1 142 ? 80.276  106.886 87.599  1.00 154.53 ? 142 ILE B C   1 
ATOM   5406  O O   . ILE B 1 142 ? 79.129  106.451 87.651  1.00 153.98 ? 142 ILE B O   1 
ATOM   5407  C CB  . ILE B 1 142 ? 82.195  105.436 86.701  1.00 152.92 ? 142 ILE B CB  1 
ATOM   5408  C CG1 . ILE B 1 142 ? 82.779  104.887 85.380  1.00 152.57 ? 142 ILE B CG1 1 
ATOM   5409  C CG2 . ILE B 1 142 ? 81.571  104.291 87.516  1.00 153.69 ? 142 ILE B CG2 1 
ATOM   5410  C CD1 . ILE B 1 142 ? 84.104  104.134 85.530  1.00 153.33 ? 142 ILE B CD1 1 
ATOM   5411  N N   . ASP B 1 143 ? 80.742  107.714 88.537  1.00 154.73 ? 143 ASP B N   1 
ATOM   5412  C CA  . ASP B 1 143 ? 79.903  108.207 89.638  1.00 153.23 ? 143 ASP B CA  1 
ATOM   5413  C C   . ASP B 1 143 ? 78.711  109.038 89.128  1.00 154.47 ? 143 ASP B C   1 
ATOM   5414  O O   . ASP B 1 143 ? 77.567  108.838 89.540  1.00 153.45 ? 143 ASP B O   1 
ATOM   5415  C CB  . ASP B 1 143 ? 80.755  109.052 90.593  1.00 153.44 ? 143 ASP B CB  1 
ATOM   5416  C CG  . ASP B 1 143 ? 79.942  109.521 91.806  1.00 155.55 ? 143 ASP B CG  1 
ATOM   5417  O OD1 . ASP B 1 143 ? 79.337  108.657 92.474  1.00 155.48 ? 143 ASP B OD1 1 
ATOM   5418  O OD2 . ASP B 1 143 ? 79.940  110.738 92.097  1.00 154.75 ? 143 ASP B OD2 1 
ATOM   5419  N N   . LYS B 1 144 ? 78.974  109.948 88.182  1.00 151.74 ? 144 LYS B N   1 
ATOM   5420  C CA  . LYS B 1 144 ? 77.985  110.832 87.549  1.00 150.34 ? 144 LYS B CA  1 
ATOM   5421  C C   . LYS B 1 144 ? 76.916  110.050 86.770  1.00 151.39 ? 144 LYS B C   1 
ATOM   5422  O O   . LYS B 1 144 ? 75.736  110.373 86.854  1.00 151.82 ? 144 LYS B O   1 
ATOM   5423  C CB  . LYS B 1 144 ? 78.775  111.813 86.669  1.00 152.16 ? 144 LYS B CB  1 
ATOM   5424  C CG  . LYS B 1 144 ? 78.005  113.028 86.137  1.00 152.01 ? 144 LYS B CG  1 
ATOM   5425  C CD  . LYS B 1 144 ? 78.889  113.899 85.223  1.00 151.56 ? 144 LYS B CD  1 
ATOM   5426  C CE  . LYS B 1 144 ? 80.130  114.472 85.928  1.00 150.89 ? 144 LYS B CE  1 
ATOM   5427  N NZ  . LYS B 1 144 ? 81.056  115.151 84.991  1.00 149.51 ? 144 LYS B NZ  1 
ATOM   5428  N N   . ASP B 1 145 ? 77.316  108.982 86.078  1.00 157.74 ? 145 ASP B N   1 
ATOM   5429  C CA  . ASP B 1 145 ? 76.425  108.038 85.387  1.00 157.63 ? 145 ASP B CA  1 
ATOM   5430  C C   . ASP B 1 145 ? 75.717  107.057 86.336  1.00 156.89 ? 145 ASP B C   1 
ATOM   5431  O O   . ASP B 1 145 ? 74.658  106.531 85.983  1.00 157.15 ? 145 ASP B O   1 
ATOM   5432  C CB  . ASP B 1 145 ? 77.217  107.248 84.331  1.00 158.64 ? 145 ASP B CB  1 
ATOM   5433  C CG  . ASP B 1 145 ? 77.630  108.065 83.098  1.00 158.71 ? 145 ASP B CG  1 
ATOM   5434  O OD1 . ASP B 1 145 ? 77.080  109.166 82.875  1.00 157.97 ? 145 ASP B OD1 1 
ATOM   5435  O OD2 . ASP B 1 145 ? 78.444  107.561 82.293  1.00 157.87 ? 145 ASP B OD2 1 
ATOM   5436  N N   . SER B 1 146 ? 76.252  106.802 87.535  1.00 158.29 ? 146 SER B N   1 
ATOM   5437  C CA  . SER B 1 146 ? 75.581  105.963 88.536  1.00 158.17 ? 146 SER B CA  1 
ATOM   5438  C C   . SER B 1 146 ? 74.409  106.661 89.243  1.00 158.81 ? 146 SER B C   1 
ATOM   5439  O O   . SER B 1 146 ? 73.628  105.987 89.915  1.00 157.61 ? 146 SER B O   1 
ATOM   5440  C CB  . SER B 1 146 ? 76.593  105.475 89.572  1.00 158.57 ? 146 SER B CB  1 
ATOM   5441  O OG  . SER B 1 146 ? 76.000  104.501 90.405  1.00 159.70 ? 146 SER B OG  1 
ATOM   5442  N N   . GLY B 1 147 ? 74.268  107.987 89.134  1.00 158.88 ? 147 GLY B N   1 
ATOM   5443  C CA  . GLY B 1 147 ? 73.122  108.722 89.693  1.00 158.02 ? 147 GLY B CA  1 
ATOM   5444  C C   . GLY B 1 147 ? 73.195  108.922 91.214  1.00 160.54 ? 147 GLY B C   1 
ATOM   5445  O O   . GLY B 1 147 ? 72.171  108.954 91.899  1.00 160.31 ? 147 GLY B O   1 
ATOM   5446  N N   . ASN B 1 148 ? 74.413  109.037 91.740  1.00 159.29 ? 148 ASN B N   1 
ATOM   5447  C CA  . ASN B 1 148 ? 74.698  109.132 93.166  1.00 158.45 ? 148 ASN B CA  1 
ATOM   5448  C C   . ASN B 1 148 ? 74.111  110.417 93.805  1.00 157.37 ? 148 ASN B C   1 
ATOM   5449  O O   . ASN B 1 148 ? 74.399  111.514 93.319  1.00 155.82 ? 148 ASN B O   1 
ATOM   5450  C CB  . ASN B 1 148 ? 76.227  109.057 93.289  1.00 157.11 ? 148 ASN B CB  1 
ATOM   5451  C CG  . ASN B 1 148 ? 76.733  108.950 94.711  1.00 157.07 ? 148 ASN B CG  1 
ATOM   5452  O OD1 . ASN B 1 148 ? 76.003  109.089 95.679  1.00 156.93 ? 148 ASN B OD1 1 
ATOM   5453  N ND2 . ASN B 1 148 ? 78.001  108.701 94.879  1.00 156.91 ? 148 ASN B ND2 1 
ATOM   5454  N N   . PRO B 1 149 ? 73.342  110.332 94.910  1.00 161.42 ? 149 PRO B N   1 
ATOM   5455  C CA  . PRO B 1 149 ? 72.843  111.503 95.639  1.00 161.62 ? 149 PRO B CA  1 
ATOM   5456  C C   . PRO B 1 149 ? 73.910  112.216 96.498  1.00 161.52 ? 149 PRO B C   1 
ATOM   5457  O O   . PRO B 1 149 ? 73.672  113.333 96.957  1.00 159.60 ? 149 PRO B O   1 
ATOM   5458  C CB  . PRO B 1 149 ? 71.699  110.963 96.507  1.00 161.48 ? 149 PRO B CB  1 
ATOM   5459  C CG  . PRO B 1 149 ? 72.122  109.527 96.792  1.00 160.59 ? 149 PRO B CG  1 
ATOM   5460  C CD  . PRO B 1 149 ? 72.801  109.110 95.490  1.00 161.28 ? 149 PRO B CD  1 
ATOM   5461  N N   . LYS B 1 150 ? 75.073  111.596 96.732  1.00 158.02 ? 150 LYS B N   1 
ATOM   5462  C CA  . LYS B 1 150 ? 76.184  112.108 97.555  1.00 155.96 ? 150 LYS B CA  1 
ATOM   5463  C C   . LYS B 1 150 ? 77.495  112.013 96.770  1.00 155.84 ? 150 LYS B C   1 
ATOM   5464  O O   . LYS B 1 150 ? 78.230  111.034 96.914  1.00 157.75 ? 150 LYS B O   1 
ATOM   5465  C CB  . LYS B 1 150 ? 76.245  111.327 98.883  1.00 155.30 ? 150 LYS B CB  1 
ATOM   5466  C CG  . LYS B 1 150 ? 75.003  111.528 99.760  1.00 155.45 ? 150 LYS B CG  1 
ATOM   5467  C CD  . LYS B 1 150 ? 75.124  110.740 101.066 1.00 156.08 ? 150 LYS B CD  1 
ATOM   5468  C CE  . LYS B 1 150 ? 73.856  110.918 101.901 1.00 156.02 ? 150 LYS B CE  1 
ATOM   5469  N NZ  . LYS B 1 150 ? 73.918  110.152 103.164 1.00 155.32 ? 150 LYS B NZ  1 
ATOM   5470  N N   . LEU B 1 151 ? 77.736  112.994 95.897  1.00 143.35 ? 151 LEU B N   1 
ATOM   5471  C CA  . LEU B 1 151 ? 78.762  112.977 94.842  1.00 144.81 ? 151 LEU B CA  1 
ATOM   5472  C C   . LEU B 1 151 ? 80.172  112.632 95.350  1.00 144.41 ? 151 LEU B C   1 
ATOM   5473  O O   . LEU B 1 151 ? 80.603  113.118 96.395  1.00 143.26 ? 151 LEU B O   1 
ATOM   5474  C CB  . LEU B 1 151 ? 78.800  114.340 94.124  1.00 145.81 ? 151 LEU B CB  1 
ATOM   5475  C CG  . LEU B 1 151 ? 77.669  114.620 93.121  1.00 146.15 ? 151 LEU B CG  1 
ATOM   5476  C CD1 . LEU B 1 151 ? 76.298  114.785 93.771  1.00 145.18 ? 151 LEU B CD1 1 
ATOM   5477  C CD2 . LEU B 1 151 ? 77.982  115.904 92.356  1.00 143.70 ? 151 LEU B CD2 1 
ATOM   5478  N N   . LEU B 1 152 ? 80.925  111.856 94.565  1.00 137.85 ? 152 LEU B N   1 
ATOM   5479  C CA  . LEU B 1 152 ? 82.231  111.306 94.943  1.00 136.04 ? 152 LEU B CA  1 
ATOM   5480  C C   . LEU B 1 152 ? 83.307  112.366 95.239  1.00 137.06 ? 152 LEU B C   1 
ATOM   5481  O O   . LEU B 1 152 ? 84.154  112.154 96.100  1.00 136.54 ? 152 LEU B O   1 
ATOM   5482  C CB  . LEU B 1 152 ? 82.640  110.310 93.845  1.00 134.88 ? 152 LEU B CB  1 
ATOM   5483  C CG  . LEU B 1 152 ? 83.981  109.594 94.040  1.00 134.74 ? 152 LEU B CG  1 
ATOM   5484  C CD1 . LEU B 1 152 ? 84.019  108.753 95.313  1.00 136.00 ? 152 LEU B CD1 1 
ATOM   5485  C CD2 . LEU B 1 152 ? 84.230  108.670 92.855  1.00 136.24 ? 152 LEU B CD2 1 
ATOM   5486  N N   . VAL B 1 153 ? 83.253  113.529 94.584  1.00 126.65 ? 153 VAL B N   1 
ATOM   5487  C CA  . VAL B 1 153 ? 84.149  114.664 94.870  1.00 125.69 ? 153 VAL B CA  1 
ATOM   5488  C C   . VAL B 1 153 ? 83.894  115.327 96.228  1.00 124.44 ? 153 VAL B C   1 
ATOM   5489  O O   . VAL B 1 153 ? 84.818  115.893 96.804  1.00 121.37 ? 153 VAL B O   1 
ATOM   5490  C CB  . VAL B 1 153 ? 84.072  115.746 93.777  1.00 122.44 ? 153 VAL B CB  1 
ATOM   5491  C CG1 . VAL B 1 153 ? 84.803  115.312 92.515  1.00 122.21 ? 153 VAL B CG1 1 
ATOM   5492  C CG2 . VAL B 1 153 ? 82.645  116.144 93.394  1.00 123.10 ? 153 VAL B CG2 1 
ATOM   5493  N N   . ASN B 1 154 ? 82.665  115.251 96.749  1.00 126.90 ? 154 ASN B N   1 
ATOM   5494  C CA  . ASN B 1 154 ? 82.250  115.906 97.996  1.00 124.79 ? 154 ASN B CA  1 
ATOM   5495  C C   . ASN B 1 154 ? 82.196  114.954 99.201  1.00 125.40 ? 154 ASN B C   1 
ATOM   5496  O O   . ASN B 1 154 ? 81.999  115.407 100.330 1.00 124.10 ? 154 ASN B O   1 
ATOM   5497  C CB  . ASN B 1 154 ? 80.911  116.634 97.769  1.00 125.09 ? 154 ASN B CB  1 
ATOM   5498  C CG  . ASN B 1 154 ? 81.003  117.757 96.757  1.00 128.03 ? 154 ASN B CG  1 
ATOM   5499  O OD1 . ASN B 1 154 ? 82.058  118.313 96.508  1.00 127.90 ? 154 ASN B OD1 1 
ATOM   5500  N ND2 . ASN B 1 154 ? 79.912  118.125 96.132  1.00 125.61 ? 154 ASN B ND2 1 
ATOM   5501  N N   . ALA B 1 155 ? 82.378  113.649 98.996  1.00 120.74 ? 155 ALA B N   1 
ATOM   5502  C CA  . ALA B 1 155 ? 82.544  112.683 100.073 1.00 117.07 ? 155 ALA B CA  1 
ATOM   5503  C C   . ALA B 1 155 ? 83.862  112.907 100.828 1.00 116.86 ? 155 ALA B C   1 
ATOM   5504  O O   . ALA B 1 155 ? 84.872  113.315 100.254 1.00 115.10 ? 155 ALA B O   1 
ATOM   5505  C CB  . ALA B 1 155 ? 82.449  111.274 99.496  1.00 117.54 ? 155 ALA B CB  1 
ATOM   5506  N N   . GLN B 1 156 ? 83.846  112.633 102.130 1.00 109.47 ? 156 GLN B N   1 
ATOM   5507  C CA  . GLN B 1 156 ? 84.917  112.976 103.065 1.00 107.57 ? 156 GLN B CA  1 
ATOM   5508  C C   . GLN B 1 156 ? 85.212  111.810 104.019 1.00 109.07 ? 156 GLN B C   1 
ATOM   5509  O O   . GLN B 1 156 ? 84.347  110.973 104.269 1.00 109.42 ? 156 GLN B O   1 
ATOM   5510  C CB  . GLN B 1 156 ? 84.503  114.197 103.897 1.00 106.83 ? 156 GLN B CB  1 
ATOM   5511  C CG  . GLN B 1 156 ? 84.202  115.494 103.126 1.00 109.33 ? 156 GLN B CG  1 
ATOM   5512  C CD  . GLN B 1 156 ? 83.018  116.233 103.746 1.00 109.30 ? 156 GLN B CD  1 
ATOM   5513  O OE1 . GLN B 1 156 ? 83.063  116.695 104.874 1.00 105.67 ? 156 GLN B OE1 1 
ATOM   5514  N NE2 . GLN B 1 156 ? 81.910  116.353 103.051 1.00 109.69 ? 156 GLN B NE2 1 
ATOM   5515  N N   . CYS B 1 157 ? 86.408  111.783 104.610 1.00 104.52 ? 157 CYS B N   1 
ATOM   5516  C CA  . CYS B 1 157 ? 86.704  110.896 105.728 1.00 104.85 ? 157 CYS B CA  1 
ATOM   5517  C C   . CYS B 1 157 ? 85.842  111.250 106.956 1.00 106.96 ? 157 CYS B C   1 
ATOM   5518  O O   . CYS B 1 157 ? 85.413  112.395 107.110 1.00 108.34 ? 157 CYS B O   1 
ATOM   5519  C CB  . CYS B 1 157 ? 88.203  110.961 106.018 1.00 102.25 ? 157 CYS B CB  1 
ATOM   5520  S SG  . CYS B 1 157 ? 89.132  110.400 104.569 1.00 99.88  ? 157 CYS B SG  1 
ATOM   5521  N N   . THR B 1 158 ? 85.566  110.275 107.826 1.00 112.36 ? 158 THR B N   1 
ATOM   5522  C CA  . THR B 1 158 ? 84.518  110.354 108.867 1.00 111.55 ? 158 THR B CA  1 
ATOM   5523  C C   . THR B 1 158 ? 84.991  110.008 110.284 1.00 108.66 ? 158 THR B C   1 
ATOM   5524  O O   . THR B 1 158 ? 84.251  110.220 111.242 1.00 104.49 ? 158 THR B O   1 
ATOM   5525  C CB  . THR B 1 158 ? 83.360  109.412 108.511 1.00 112.21 ? 158 THR B CB  1 
ATOM   5526  O OG1 . THR B 1 158 ? 83.858  108.114 108.299 1.00 114.13 ? 158 THR B OG1 1 
ATOM   5527  C CG2 . THR B 1 158 ? 82.613  109.825 107.256 1.00 108.92 ? 158 THR B CG2 1 
ATOM   5528  N N   . ASP B 1 159 ? 86.196  109.470 110.455 1.00 110.87 ? 159 ASP B N   1 
ATOM   5529  C CA  . ASP B 1 159 ? 86.753  109.102 111.762 1.00 108.99 ? 159 ASP B CA  1 
ATOM   5530  C C   . ASP B 1 159 ? 87.253  110.325 112.548 1.00 107.91 ? 159 ASP B C   1 
ATOM   5531  O O   . ASP B 1 159 ? 87.501  111.384 111.985 1.00 110.10 ? 159 ASP B O   1 
ATOM   5532  C CB  . ASP B 1 159 ? 87.901  108.119 111.547 1.00 109.06 ? 159 ASP B CB  1 
ATOM   5533  C CG  . ASP B 1 159 ? 88.996  108.752 110.693 1.00 113.11 ? 159 ASP B CG  1 
ATOM   5534  O OD1 . ASP B 1 159 ? 88.873  108.685 109.446 1.00 113.61 ? 159 ASP B OD1 1 
ATOM   5535  O OD2 . ASP B 1 159 ? 89.924  109.340 111.290 1.00 114.25 ? 159 ASP B OD2 1 
ATOM   5536  N N   . GLU B 1 160 ? 87.443  110.188 113.859 1.00 103.65 ? 160 GLU B N   1 
ATOM   5537  C CA  . GLU B 1 160 ? 87.770  111.313 114.739 1.00 102.68 ? 160 GLU B CA  1 
ATOM   5538  C C   . GLU B 1 160 ? 89.096  112.024 114.422 1.00 103.79 ? 160 GLU B C   1 
ATOM   5539  O O   . GLU B 1 160 ? 89.270  113.168 114.841 1.00 104.89 ? 160 GLU B O   1 
ATOM   5540  C CB  . GLU B 1 160 ? 87.717  110.863 116.212 1.00 102.33 ? 160 GLU B CB  1 
ATOM   5541  C CG  . GLU B 1 160 ? 88.848  109.937 116.702 1.00 106.11 ? 160 GLU B CG  1 
ATOM   5542  C CD  . GLU B 1 160 ? 88.743  108.465 116.257 1.00 109.91 ? 160 GLU B CD  1 
ATOM   5543  O OE1 . GLU B 1 160 ? 87.708  108.057 115.680 1.00 110.06 ? 160 GLU B OE1 1 
ATOM   5544  O OE2 . GLU B 1 160 ? 89.697  107.701 116.521 1.00 105.25 ? 160 GLU B OE2 1 
ATOM   5545  N N   . PHE B 1 161 ? 90.028  111.403 113.693 1.00 91.18  ? 161 PHE B N   1 
ATOM   5546  C CA  . PHE B 1 161 ? 91.278  112.043 113.288 1.00 91.65  ? 161 PHE B CA  1 
ATOM   5547  C C   . PHE B 1 161 ? 91.170  112.732 111.936 1.00 92.34  ? 161 PHE B C   1 
ATOM   5548  O O   . PHE B 1 161 ? 91.560  113.892 111.836 1.00 91.63  ? 161 PHE B O   1 
ATOM   5549  C CB  . PHE B 1 161 ? 92.428  111.039 113.308 1.00 87.64  ? 161 PHE B CB  1 
ATOM   5550  C CG  . PHE B 1 161 ? 92.944  110.777 114.702 1.00 92.97  ? 161 PHE B CG  1 
ATOM   5551  C CD1 . PHE B 1 161 ? 93.862  111.672 115.278 1.00 93.75  ? 161 PHE B CD1 1 
ATOM   5552  C CD2 . PHE B 1 161 ? 92.509  109.660 115.430 1.00 93.11  ? 161 PHE B CD2 1 
ATOM   5553  C CE1 . PHE B 1 161 ? 94.346  111.448 116.574 1.00 92.63  ? 161 PHE B CE1 1 
ATOM   5554  C CE2 . PHE B 1 161 ? 92.999  109.429 116.726 1.00 94.15  ? 161 PHE B CE2 1 
ATOM   5555  C CZ  . PHE B 1 161 ? 93.921  110.322 117.296 1.00 96.67  ? 161 PHE B CZ  1 
ATOM   5556  N N   . TYR B 1 162 ? 90.617  112.083 110.916 1.00 94.28  ? 162 TYR B N   1 
ATOM   5557  C CA  . TYR B 1 162 ? 90.608  112.615 109.551 1.00 92.67  ? 162 TYR B CA  1 
ATOM   5558  C C   . TYR B 1 162 ? 89.263  113.203 109.108 1.00 95.07  ? 162 TYR B C   1 
ATOM   5559  O O   . TYR B 1 162 ? 89.087  113.477 107.927 1.00 99.54  ? 162 TYR B O   1 
ATOM   5560  C CB  . TYR B 1 162 ? 91.172  111.584 108.564 1.00 90.67  ? 162 TYR B CB  1 
ATOM   5561  C CG  . TYR B 1 162 ? 92.526  111.048 108.988 1.00 91.91  ? 162 TYR B CG  1 
ATOM   5562  C CD1 . TYR B 1 162 ? 93.651  111.894 108.972 1.00 92.59  ? 162 TYR B CD1 1 
ATOM   5563  C CD2 . TYR B 1 162 ? 92.647  109.738 109.482 1.00 91.98  ? 162 TYR B CD2 1 
ATOM   5564  C CE1 . TYR B 1 162 ? 94.880  111.443 109.482 1.00 93.00  ? 162 TYR B CE1 1 
ATOM   5565  C CE2 . TYR B 1 162 ? 93.874  109.288 110.004 1.00 92.47  ? 162 TYR B CE2 1 
ATOM   5566  C CZ  . TYR B 1 162 ? 94.987  110.150 110.022 1.00 90.55  ? 162 TYR B CZ  1 
ATOM   5567  O OH  . TYR B 1 162 ? 96.156  109.742 110.566 1.00 85.47  ? 162 TYR B OH  1 
ATOM   5568  N N   . GLN B 1 163 ? 88.310  113.439 110.013 1.00 100.78 ? 163 GLN B N   1 
ATOM   5569  C CA  . GLN B 1 163 ? 86.978  113.935 109.655 1.00 98.90  ? 163 GLN B CA  1 
ATOM   5570  C C   . GLN B 1 163 ? 87.021  115.142 108.709 1.00 96.90  ? 163 GLN B C   1 
ATOM   5571  O O   . GLN B 1 163 ? 87.752  116.106 108.936 1.00 99.36  ? 163 GLN B O   1 
ATOM   5572  C CB  . GLN B 1 163 ? 86.155  114.257 110.911 1.00 98.73  ? 163 GLN B CB  1 
ATOM   5573  C CG  . GLN B 1 163 ? 84.685  114.536 110.580 1.00 98.27  ? 163 GLN B CG  1 
ATOM   5574  C CD  . GLN B 1 163 ? 83.798  114.568 111.822 1.00 104.39 ? 163 GLN B CD  1 
ATOM   5575  O OE1 . GLN B 1 163 ? 84.248  114.587 112.957 1.00 103.48 ? 163 GLN B OE1 1 
ATOM   5576  N NE2 . GLN B 1 163 ? 82.498  114.591 111.653 1.00 101.68 ? 163 GLN B NE2 1 
ATOM   5577  N N   . GLY B 1 164 ? 86.235  115.096 107.638 1.00 90.97  ? 164 GLY B N   1 
ATOM   5578  C CA  . GLY B 1 164 ? 86.118  116.187 106.673 1.00 90.65  ? 164 GLY B CA  1 
ATOM   5579  C C   . GLY B 1 164 ? 87.247  116.269 105.642 1.00 90.74  ? 164 GLY B C   1 
ATOM   5580  O O   . GLY B 1 164 ? 87.149  117.051 104.700 1.00 94.62  ? 164 GLY B O   1 
ATOM   5581  N N   . HIS B 1 165 ? 88.304  115.467 105.774 1.00 81.84  ? 165 HIS B N   1 
ATOM   5582  C CA  . HIS B 1 165 ? 89.355  115.348 104.758 1.00 79.65  ? 165 HIS B CA  1 
ATOM   5583  C C   . HIS B 1 165 ? 88.783  114.854 103.433 1.00 80.81  ? 165 HIS B C   1 
ATOM   5584  O O   . HIS B 1 165 ? 87.938  113.959 103.421 1.00 89.34  ? 165 HIS B O   1 
ATOM   5585  C CB  . HIS B 1 165 ? 90.426  114.387 105.257 1.00 86.54  ? 165 HIS B CB  1 
ATOM   5586  C CG  . HIS B 1 165 ? 91.605  114.247 104.344 1.00 89.59  ? 165 HIS B CG  1 
ATOM   5587  N ND1 . HIS B 1 165 ? 92.300  115.307 103.779 1.00 88.03  ? 165 HIS B ND1 1 
ATOM   5588  C CD2 . HIS B 1 165 ? 92.231  113.083 104.027 1.00 89.53  ? 165 HIS B CD2 1 
ATOM   5589  C CE1 . HIS B 1 165 ? 93.325  114.758 103.117 1.00 84.91  ? 165 HIS B CE1 1 
ATOM   5590  N NE2 . HIS B 1 165 ? 93.312  113.425 103.254 1.00 83.44  ? 165 HIS B NE2 1 
ATOM   5591  N N   . SER B 1 166 ? 89.222  115.418 102.315 1.00 79.39  ? 166 SER B N   1 
ATOM   5592  C CA  . SER B 1 166 ? 88.629  115.174 100.999 1.00 85.41  ? 166 SER B CA  1 
ATOM   5593  C C   . SER B 1 166 ? 89.688  115.017 99.920  1.00 86.49  ? 166 SER B C   1 
ATOM   5594  O O   . SER B 1 166 ? 90.838  115.420 100.082 1.00 89.31  ? 166 SER B O   1 
ATOM   5595  C CB  . SER B 1 166 ? 87.645  116.291 100.625 1.00 90.27  ? 166 SER B CB  1 
ATOM   5596  O OG  . SER B 1 166 ? 88.314  117.419 100.096 1.00 86.54  ? 166 SER B OG  1 
ATOM   5597  N N   . ALA B 1 167 ? 89.298  114.465 98.775  1.00 92.26  ? 167 ALA B N   1 
ATOM   5598  C CA  . ALA B 1 167 ? 90.192  114.310 97.627  1.00 94.42  ? 167 ALA B CA  1 
ATOM   5599  C C   . ALA B 1 167 ? 90.834  115.635 97.180  1.00 94.30  ? 167 ALA B C   1 
ATOM   5600  O O   . ALA B 1 167 ? 91.980  115.634 96.737  1.00 95.55  ? 167 ALA B O   1 
ATOM   5601  C CB  . ALA B 1 167 ? 89.393  113.670 96.496  1.00 94.13  ? 167 ALA B CB  1 
ATOM   5602  N N   . LEU B 1 168 ? 90.138  116.771 97.318  1.00 89.54  ? 168 LEU B N   1 
ATOM   5603  C CA  . LEU B 1 168 ? 90.687  118.090 96.994  1.00 91.67  ? 168 LEU B CA  1 
ATOM   5604  C C   . LEU B 1 168 ? 91.811  118.501 97.956  1.00 91.84  ? 168 LEU B C   1 
ATOM   5605  O O   . LEU B 1 168 ? 92.849  118.975 97.509  1.00 97.16  ? 168 LEU B O   1 
ATOM   5606  C CB  . LEU B 1 168 ? 89.536  119.110 96.940  1.00 90.57  ? 168 LEU B CB  1 
ATOM   5607  C CG  . LEU B 1 168 ? 89.955  120.555 96.619  1.00 89.02  ? 168 LEU B CG  1 
ATOM   5608  C CD1 . LEU B 1 168 ? 90.647  120.687 95.264  1.00 87.42  ? 168 LEU B CD1 1 
ATOM   5609  C CD2 . LEU B 1 168 ? 88.725  121.451 96.588  1.00 90.92  ? 168 LEU B CD2 1 
ATOM   5610  N N   . HIS B 1 169 ? 91.689  118.240 99.260  1.00 76.73  ? 169 HIS B N   1 
ATOM   5611  C CA  . HIS B 1 169 ? 92.801  118.443 100.193 1.00 76.54  ? 169 HIS B CA  1 
ATOM   5612  C C   . HIS B 1 169 ? 93.997  117.524 99.898  1.00 82.99  ? 169 HIS B C   1 
ATOM   5613  O O   . HIS B 1 169 ? 95.142  117.911 100.125 1.00 83.80  ? 169 HIS B O   1 
ATOM   5614  C CB  . HIS B 1 169 ? 92.341  118.220 101.631 1.00 76.35  ? 169 HIS B CB  1 
ATOM   5615  C CG  . HIS B 1 169 ? 91.210  119.087 102.102 1.00 77.51  ? 169 HIS B CG  1 
ATOM   5616  N ND1 . HIS B 1 169 ? 89.857  118.809 101.938 1.00 80.17  ? 169 HIS B ND1 1 
ATOM   5617  C CD2 . HIS B 1 169 ? 91.343  120.203 102.873 1.00 78.61  ? 169 HIS B CD2 1 
ATOM   5618  C CE1 . HIS B 1 169 ? 89.206  119.759 102.622 1.00 79.00  ? 169 HIS B CE1 1 
ATOM   5619  N NE2 . HIS B 1 169 ? 90.073  120.606 103.191 1.00 80.70  ? 169 HIS B NE2 1 
ATOM   5620  N N   . ILE B 1 170 ? 93.775  116.313 99.379  1.00 91.77  ? 170 ILE B N   1 
ATOM   5621  C CA  . ILE B 1 170 ? 94.866  115.438 98.922  1.00 91.30  ? 170 ILE B CA  1 
ATOM   5622  C C   . ILE B 1 170 ? 95.527  116.034 97.680  1.00 93.97  ? 170 ILE B C   1 
ATOM   5623  O O   . ILE B 1 170 ? 96.748  116.155 97.633  1.00 96.47  ? 170 ILE B O   1 
ATOM   5624  C CB  . ILE B 1 170 ? 94.392  113.993 98.658  1.00 86.38  ? 170 ILE B CB  1 
ATOM   5625  C CG1 . ILE B 1 170 ? 93.751  113.382 99.915  1.00 87.13  ? 170 ILE B CG1 1 
ATOM   5626  C CG2 . ILE B 1 170 ? 95.568  113.110 98.219  1.00 86.64  ? 170 ILE B CG2 1 
ATOM   5627  C CD1 . ILE B 1 170 ? 93.132  112.008 99.688  1.00 89.82  ? 170 ILE B CD1 1 
ATOM   5628  N N   . ALA B 1 171 ? 94.740  116.458 96.694  1.00 89.33  ? 171 ALA B N   1 
ATOM   5629  C CA  . ALA B 1 171 ? 95.243  117.046 95.455  1.00 84.50  ? 171 ALA B CA  1 
ATOM   5630  C C   . ALA B 1 171 ? 96.117  118.284 95.701  1.00 87.18  ? 171 ALA B C   1 
ATOM   5631  O O   . ALA B 1 171 ? 97.149  118.459 95.056  1.00 88.64  ? 171 ALA B O   1 
ATOM   5632  C CB  . ALA B 1 171 ? 94.044  117.389 94.571  1.00 82.21  ? 171 ALA B CB  1 
ATOM   5633  N N   . ILE B 1 172 ? 95.727  119.137 96.646  1.00 87.94  ? 172 ILE B N   1 
ATOM   5634  C CA  . ILE B 1 172 ? 96.494  120.329 96.998  1.00 82.72  ? 172 ILE B CA  1 
ATOM   5635  C C   . ILE B 1 172 ? 97.766  119.953 97.760  1.00 85.10  ? 172 ILE B C   1 
ATOM   5636  O O   . ILE B 1 172 ? 98.826  120.474 97.434  1.00 86.36  ? 172 ILE B O   1 
ATOM   5637  C CB  . ILE B 1 172 ? 95.622  121.335 97.769  1.00 79.10  ? 172 ILE B CB  1 
ATOM   5638  C CG1 . ILE B 1 172 ? 94.445  121.811 96.898  1.00 82.87  ? 172 ILE B CG1 1 
ATOM   5639  C CG2 . ILE B 1 172 ? 96.447  122.559 98.188  1.00 82.80  ? 172 ILE B CG2 1 
ATOM   5640  C CD1 . ILE B 1 172 ? 93.321  122.451 97.691  1.00 81.25  ? 172 ILE B CD1 1 
ATOM   5641  N N   . GLU B 1 173 ? 97.734  119.034 98.728  1.00 92.57  ? 173 GLU B N   1 
ATOM   5642  C CA  . GLU B 1 173 ? 98.957  118.650 99.450  1.00 90.29  ? 173 GLU B CA  1 
ATOM   5643  C C   . GLU B 1 173 ? 99.972  117.939 98.551  1.00 93.68  ? 173 GLU B C   1 
ATOM   5644  O O   . GLU B 1 173 ? 101.166 118.217 98.642  1.00 95.59  ? 173 GLU B O   1 
ATOM   5645  C CB  . GLU B 1 173 ? 98.615  117.799 100.675 1.00 92.49  ? 173 GLU B CB  1 
ATOM   5646  C CG  . GLU B 1 173 ? 99.839  117.513 101.566 1.00 95.30  ? 173 GLU B CG  1 
ATOM   5647  C CD  . GLU B 1 173 ? 100.735 116.337 101.120 1.00 100.14 ? 173 GLU B CD  1 
ATOM   5648  O OE1 . GLU B 1 173 ? 100.278 115.428 100.389 1.00 100.32 ? 173 GLU B OE1 1 
ATOM   5649  O OE2 . GLU B 1 173 ? 101.909 116.303 101.555 1.00 97.34  ? 173 GLU B OE2 1 
ATOM   5650  N N   . LYS B 1 174 ? 99.506  117.101 97.620  1.00 97.20  ? 174 LYS B N   1 
ATOM   5651  C CA  . LYS B 1 174 ? 100.309 116.479 96.550  1.00 95.22  ? 174 LYS B CA  1 
ATOM   5652  C C   . LYS B 1 174 ? 100.775 117.475 95.471  1.00 98.04  ? 174 LYS B C   1 
ATOM   5653  O O   . LYS B 1 174 ? 101.450 117.075 94.525  1.00 95.82  ? 174 LYS B O   1 
ATOM   5654  C CB  . LYS B 1 174 ? 99.514  115.301 95.957  1.00 94.13  ? 174 LYS B CB  1 
ATOM   5655  C CG  . LYS B 1 174 ? 99.324  114.143 96.953  1.00 97.35  ? 174 LYS B CG  1 
ATOM   5656  C CD  . LYS B 1 174 ? 100.601 113.319 97.152  1.00 99.27  ? 174 LYS B CD  1 
ATOM   5657  C CE  . LYS B 1 174 ? 100.483 112.332 98.319  1.00 99.54  ? 174 LYS B CE  1 
ATOM   5658  N NZ  . LYS B 1 174 ? 100.975 112.904 99.595  1.00 95.09  ? 174 LYS B NZ  1 
ATOM   5659  N N   . ARG B 1 175 ? 100.450 118.767 95.593  1.00 96.20  ? 175 ARG B N   1 
ATOM   5660  C CA  . ARG B 1 175 ? 100.876 119.891 94.732  1.00 90.42  ? 175 ARG B CA  1 
ATOM   5661  C C   . ARG B 1 175 ? 100.448 119.824 93.260  1.00 91.77  ? 175 ARG B C   1 
ATOM   5662  O O   . ARG B 1 175 ? 101.081 120.449 92.409  1.00 92.66  ? 175 ARG B O   1 
ATOM   5663  C CB  . ARG B 1 175 ? 102.384 120.178 94.874  1.00 93.04  ? 175 ARG B CB  1 
ATOM   5664  C CG  . ARG B 1 175 ? 102.860 120.354 96.315  1.00 92.08  ? 175 ARG B CG  1 
ATOM   5665  C CD  . ARG B 1 175 ? 104.352 120.702 96.370  1.00 91.61  ? 175 ARG B CD  1 
ATOM   5666  N NE  . ARG B 1 175 ? 104.648 122.052 95.850  1.00 99.96  ? 175 ARG B NE  1 
ATOM   5667  C CZ  . ARG B 1 175 ? 104.544 123.191 96.504  1.00 97.15  ? 175 ARG B CZ  1 
ATOM   5668  N NH1 . ARG B 1 175 ? 104.898 124.309 95.947  1.00 91.31  ? 175 ARG B NH1 1 
ATOM   5669  N NH2 . ARG B 1 175 ? 104.086 123.229 97.717  1.00 92.60  ? 175 ARG B NH2 1 
ATOM   5670  N N   . SER B 1 176 ? 99.399  119.078 92.919  1.00 106.64 ? 176 SER B N   1 
ATOM   5671  C CA  . SER B 1 176 ? 98.954  118.958 91.524  1.00 108.42 ? 176 SER B CA  1 
ATOM   5672  C C   . SER B 1 176 ? 97.879  119.984 91.175  1.00 107.17 ? 176 SER B C   1 
ATOM   5673  O O   . SER B 1 176 ? 96.689  119.762 91.399  1.00 108.10 ? 176 SER B O   1 
ATOM   5674  C CB  . SER B 1 176 ? 98.490  117.537 91.214  1.00 108.72 ? 176 SER B CB  1 
ATOM   5675  O OG  . SER B 1 176 ? 98.021  117.488 89.877  1.00 109.80 ? 176 SER B OG  1 
ATOM   5676  N N   . LEU B 1 177 ? 98.276  121.095 90.549  1.00 108.37 ? 177 LEU B N   1 
ATOM   5677  C CA  . LEU B 1 177 ? 97.326  122.046 89.966  1.00 111.60 ? 177 LEU B CA  1 
ATOM   5678  C C   . LEU B 1 177 ? 96.430  121.367 88.922  1.00 110.50 ? 177 LEU B C   1 
ATOM   5679  O O   . LEU B 1 177 ? 95.240  121.653 88.852  1.00 112.12 ? 177 LEU B O   1 
ATOM   5680  C CB  . LEU B 1 177 ? 98.100  123.228 89.357  1.00 112.46 ? 177 LEU B CB  1 
ATOM   5681  C CG  . LEU B 1 177 ? 97.213  124.260 88.633  1.00 109.51 ? 177 LEU B CG  1 
ATOM   5682  C CD1 . LEU B 1 177 ? 96.262  124.978 89.587  1.00 108.01 ? 177 LEU B CD1 1 
ATOM   5683  C CD2 . LEU B 1 177 ? 98.085  125.308 87.951  1.00 107.01 ? 177 LEU B CD2 1 
ATOM   5684  N N   . GLN B 1 178 ? 96.975  120.433 88.137  1.00 114.56 ? 178 GLN B N   1 
ATOM   5685  C CA  . GLN B 1 178 ? 96.222  119.682 87.133  1.00 114.35 ? 178 GLN B CA  1 
ATOM   5686  C C   . GLN B 1 178 ? 95.087  118.865 87.767  1.00 113.36 ? 178 GLN B C   1 
ATOM   5687  O O   . GLN B 1 178 ? 93.977  118.834 87.236  1.00 112.43 ? 178 GLN B O   1 
ATOM   5688  C CB  . GLN B 1 178 ? 97.173  118.752 86.357  1.00 113.21 ? 178 GLN B CB  1 
ATOM   5689  C CG  . GLN B 1 178 ? 98.106  119.471 85.367  1.00 114.33 ? 178 GLN B CG  1 
ATOM   5690  C CD  . GLN B 1 178 ? 99.274  120.234 85.986  1.00 114.82 ? 178 GLN B CD  1 
ATOM   5691  O OE1 . GLN B 1 178 ? 99.630  120.084 87.148  1.00 113.79 ? 178 GLN B OE1 1 
ATOM   5692  N NE2 . GLN B 1 178 ? 99.921  121.092 85.236  1.00 113.85 ? 178 GLN B NE2 1 
ATOM   5693  N N   . CYS B 1 179 ? 95.329  118.247 88.922  1.00 111.40 ? 179 CYS B N   1 
ATOM   5694  C CA  . CYS B 1 179 ? 94.305  117.501 89.635  1.00 110.65 ? 179 CYS B CA  1 
ATOM   5695  C C   . CYS B 1 179 ? 93.310  118.429 90.358  1.00 113.97 ? 179 CYS B C   1 
ATOM   5696  O O   . CYS B 1 179 ? 92.107  118.177 90.307  1.00 112.97 ? 179 CYS B O   1 
ATOM   5697  C CB  . CYS B 1 179 ? 95.004  116.511 90.566  1.00 112.86 ? 179 CYS B CB  1 
ATOM   5698  S SG  . CYS B 1 179 ? 93.790  115.304 91.135  1.00 122.79 ? 179 CYS B SG  1 
ATOM   5699  N N   . VAL B 1 180 ? 93.761  119.548 90.943  1.00 106.09 ? 180 VAL B N   1 
ATOM   5700  C CA  . VAL B 1 180 ? 92.857  120.563 91.520  1.00 104.52 ? 180 VAL B CA  1 
ATOM   5701  C C   . VAL B 1 180 ? 91.869  121.077 90.478  1.00 105.26 ? 180 VAL B C   1 
ATOM   5702  O O   . VAL B 1 180 ? 90.664  121.063 90.713  1.00 103.82 ? 180 VAL B O   1 
ATOM   5703  C CB  . VAL B 1 180 ? 93.643  121.727 92.139  1.00 102.29 ? 180 VAL B CB  1 
ATOM   5704  C CG1 . VAL B 1 180 ? 92.744  122.907 92.508  1.00 105.33 ? 180 VAL B CG1 1 
ATOM   5705  C CG2 . VAL B 1 180 ? 94.340  121.268 93.413  1.00 101.61 ? 180 VAL B CG2 1 
ATOM   5706  N N   . LYS B 1 181 ? 92.362  121.463 89.299  1.00 111.00 ? 181 LYS B N   1 
ATOM   5707  C CA  . LYS B 1 181 ? 91.521  121.844 88.162  1.00 107.80 ? 181 LYS B CA  1 
ATOM   5708  C C   . LYS B 1 181 ? 90.522  120.739 87.813  1.00 111.09 ? 181 LYS B C   1 
ATOM   5709  O O   . LYS B 1 181 ? 89.329  120.999 87.763  1.00 110.43 ? 181 LYS B O   1 
ATOM   5710  C CB  . LYS B 1 181 ? 92.400  122.170 86.946  1.00 105.16 ? 181 LYS B CB  1 
ATOM   5711  C CG  . LYS B 1 181 ? 93.126  123.509 87.101  1.00 110.28 ? 181 LYS B CG  1 
ATOM   5712  C CD  . LYS B 1 181 ? 94.027  123.786 85.896  1.00 111.07 ? 181 LYS B CD  1 
ATOM   5713  C CE  . LYS B 1 181 ? 94.597  125.202 85.965  1.00 111.96 ? 181 LYS B CE  1 
ATOM   5714  N NZ  . LYS B 1 181 ? 95.368  125.532 84.746  1.00 108.69 ? 181 LYS B NZ  1 
ATOM   5715  N N   . LEU B 1 182 ? 90.973  119.502 87.600  1.00 117.54 ? 182 LEU B N   1 
ATOM   5716  C CA  . LEU B 1 182 ? 90.095  118.391 87.226  1.00 114.53 ? 182 LEU B CA  1 
ATOM   5717  C C   . LEU B 1 182 ? 88.975  118.134 88.255  1.00 116.08 ? 182 LEU B C   1 
ATOM   5718  O O   . LEU B 1 182 ? 87.832  117.869 87.879  1.00 116.84 ? 182 LEU B O   1 
ATOM   5719  C CB  . LEU B 1 182 ? 90.981  117.150 87.007  1.00 116.23 ? 182 LEU B CB  1 
ATOM   5720  C CG  . LEU B 1 182 ? 90.230  115.866 86.623  1.00 117.58 ? 182 LEU B CG  1 
ATOM   5721  C CD1 . LEU B 1 182 ? 89.465  116.004 85.312  1.00 116.56 ? 182 LEU B CD1 1 
ATOM   5722  C CD2 . LEU B 1 182 ? 91.233  114.730 86.453  1.00 115.41 ? 182 LEU B CD2 1 
ATOM   5723  N N   . LEU B 1 183 ? 89.280  118.224 89.549  1.00 108.77 ? 183 LEU B N   1 
ATOM   5724  C CA  . LEU B 1 183 ? 88.302  118.065 90.625  1.00 110.13 ? 183 LEU B CA  1 
ATOM   5725  C C   . LEU B 1 183 ? 87.299  119.226 90.676  1.00 111.60 ? 183 LEU B C   1 
ATOM   5726  O O   . LEU B 1 183 ? 86.092  118.992 90.728  1.00 108.26 ? 183 LEU B O   1 
ATOM   5727  C CB  . LEU B 1 183 ? 89.049  117.941 91.965  1.00 110.15 ? 183 LEU B CB  1 
ATOM   5728  C CG  . LEU B 1 183 ? 89.821  116.626 92.152  1.00 106.70 ? 183 LEU B CG  1 
ATOM   5729  C CD1 . LEU B 1 183 ? 90.714  116.741 93.380  1.00 106.17 ? 183 LEU B CD1 1 
ATOM   5730  C CD2 . LEU B 1 183 ? 88.874  115.450 92.372  1.00 110.44 ? 183 LEU B CD2 1 
ATOM   5731  N N   . VAL B 1 184 ? 87.776  120.473 90.648  1.00 115.57 ? 184 VAL B N   1 
ATOM   5732  C CA  . VAL B 1 184 ? 86.920  121.670 90.718  1.00 112.66 ? 184 VAL B CA  1 
ATOM   5733  C C   . VAL B 1 184 ? 86.055  121.827 89.462  1.00 112.23 ? 184 VAL B C   1 
ATOM   5734  O O   . VAL B 1 184 ? 84.874  122.155 89.572  1.00 113.04 ? 184 VAL B O   1 
ATOM   5735  C CB  . VAL B 1 184 ? 87.776  122.919 90.989  1.00 109.50 ? 184 VAL B CB  1 
ATOM   5736  C CG1 . VAL B 1 184 ? 86.976  124.219 90.890  1.00 111.27 ? 184 VAL B CG1 1 
ATOM   5737  C CG2 . VAL B 1 184 ? 88.377  122.875 92.397  1.00 111.41 ? 184 VAL B CG2 1 
ATOM   5738  N N   . GLU B 1 185 ? 86.575  121.507 88.275  1.00 113.59 ? 185 GLU B N   1 
ATOM   5739  C CA  . GLU B 1 185 ? 85.790  121.446 87.030  1.00 114.89 ? 185 GLU B CA  1 
ATOM   5740  C C   . GLU B 1 185 ? 84.637  120.433 87.108  1.00 118.09 ? 185 GLU B C   1 
ATOM   5741  O O   . GLU B 1 185 ? 83.571  120.663 86.541  1.00 119.45 ? 185 GLU B O   1 
ATOM   5742  C CB  . GLU B 1 185 ? 86.708  121.074 85.855  1.00 115.29 ? 185 GLU B CB  1 
ATOM   5743  C CG  . GLU B 1 185 ? 87.591  122.249 85.409  1.00 117.19 ? 185 GLU B CG  1 
ATOM   5744  C CD  . GLU B 1 185 ? 88.720  121.857 84.437  1.00 119.55 ? 185 GLU B CD  1 
ATOM   5745  O OE1 . GLU B 1 185 ? 88.712  120.738 83.877  1.00 119.23 ? 185 GLU B OE1 1 
ATOM   5746  O OE2 . GLU B 1 185 ? 89.601  122.707 84.178  1.00 118.53 ? 185 GLU B OE2 1 
ATOM   5747  N N   . ASN B 1 186 ? 84.813  119.327 87.834  1.00 121.38 ? 186 ASN B N   1 
ATOM   5748  C CA  . ASN B 1 186 ? 83.760  118.342 88.099  1.00 120.53 ? 186 ASN B CA  1 
ATOM   5749  C C   . ASN B 1 186 ? 82.915  118.645 89.351  1.00 120.44 ? 186 ASN B C   1 
ATOM   5750  O O   . ASN B 1 186 ? 82.102  117.817 89.764  1.00 117.17 ? 186 ASN B O   1 
ATOM   5751  C CB  . ASN B 1 186 ? 84.384  116.942 88.088  1.00 120.06 ? 186 ASN B CB  1 
ATOM   5752  C CG  . ASN B 1 186 ? 84.642  116.496 86.664  1.00 122.07 ? 186 ASN B CG  1 
ATOM   5753  O OD1 . ASN B 1 186 ? 83.740  116.036 85.974  1.00 124.20 ? 186 ASN B OD1 1 
ATOM   5754  N ND2 . ASN B 1 186 ? 85.851  116.641 86.179  1.00 121.19 ? 186 ASN B ND2 1 
ATOM   5755  N N   . GLY B 1 187 ? 83.049  119.839 89.933  1.00 117.40 ? 187 GLY B N   1 
ATOM   5756  C CA  . GLY B 1 187 ? 82.176  120.324 91.007  1.00 115.80 ? 187 GLY B CA  1 
ATOM   5757  C C   . GLY B 1 187 ? 82.610  119.977 92.433  1.00 116.56 ? 187 GLY B C   1 
ATOM   5758  O O   . GLY B 1 187 ? 81.765  119.983 93.327  1.00 113.65 ? 187 GLY B O   1 
ATOM   5759  N N   . ALA B 1 188 ? 83.891  119.678 92.662  1.00 115.74 ? 188 ALA B N   1 
ATOM   5760  C CA  . ALA B 1 188 ? 84.424  119.501 94.011  1.00 116.09 ? 188 ALA B CA  1 
ATOM   5761  C C   . ALA B 1 188 ? 84.250  120.773 94.849  1.00 114.51 ? 188 ALA B C   1 
ATOM   5762  O O   . ALA B 1 188 ? 84.719  121.840 94.457  1.00 115.47 ? 188 ALA B O   1 
ATOM   5763  C CB  . ALA B 1 188 ? 85.904  119.120 93.929  1.00 116.02 ? 188 ALA B CB  1 
ATOM   5764  N N   . ASP B 1 189 ? 83.580  120.671 95.994  1.00 112.26 ? 189 ASP B N   1 
ATOM   5765  C CA  . ASP B 1 189 ? 83.282  121.821 96.841  1.00 112.03 ? 189 ASP B CA  1 
ATOM   5766  C C   . ASP B 1 189 ? 84.559  122.415 97.455  1.00 114.47 ? 189 ASP B C   1 
ATOM   5767  O O   . ASP B 1 189 ? 85.226  121.812 98.294  1.00 113.04 ? 189 ASP B O   1 
ATOM   5768  C CB  . ASP B 1 189 ? 82.229  121.449 97.891  1.00 110.14 ? 189 ASP B CB  1 
ATOM   5769  C CG  . ASP B 1 189 ? 81.868  122.605 98.838  1.00 113.47 ? 189 ASP B CG  1 
ATOM   5770  O OD1 . ASP B 1 189 ? 82.239  123.768 98.561  1.00 115.63 ? 189 ASP B OD1 1 
ATOM   5771  O OD2 . ASP B 1 189 ? 81.160  122.345 99.834  1.00 113.24 ? 189 ASP B OD2 1 
ATOM   5772  N N   . VAL B 1 190 ? 84.896  123.630 97.041  1.00 104.43 ? 190 VAL B N   1 
ATOM   5773  C CA  . VAL B 1 190 ? 86.080  124.373 97.472  1.00 99.99  ? 190 VAL B CA  1 
ATOM   5774  C C   . VAL B 1 190 ? 86.024  124.780 98.952  1.00 101.91 ? 190 VAL B C   1 
ATOM   5775  O O   . VAL B 1 190 ? 87.045  125.167 99.509  1.00 102.62 ? 190 VAL B O   1 
ATOM   5776  C CB  . VAL B 1 190 ? 86.263  125.570 96.518  1.00 99.69  ? 190 VAL B CB  1 
ATOM   5777  C CG1 . VAL B 1 190 ? 87.321  126.576 96.945  1.00 106.26 ? 190 VAL B CG1 1 
ATOM   5778  C CG2 . VAL B 1 190 ? 86.662  125.080 95.125  1.00 100.31 ? 190 VAL B CG2 1 
ATOM   5779  N N   . HIS B 1 191 ? 84.874  124.667 99.629  1.00 100.19 ? 191 HIS B N   1 
ATOM   5780  C CA  . HIS B 1 191 ? 84.701  125.081 101.027 1.00 97.99  ? 191 HIS B CA  1 
ATOM   5781  C C   . HIS B 1 191 ? 84.547  123.920 102.023 1.00 100.82 ? 191 HIS B C   1 
ATOM   5782  O O   . HIS B 1 191 ? 84.093  124.125 103.149 1.00 102.76 ? 191 HIS B O   1 
ATOM   5783  C CB  . HIS B 1 191 ? 83.568  126.111 101.148 1.00 102.28 ? 191 HIS B CB  1 
ATOM   5784  C CG  . HIS B 1 191 ? 83.776  127.348 100.313 1.00 105.24 ? 191 HIS B CG  1 
ATOM   5785  N ND1 . HIS B 1 191 ? 83.356  127.534 99.020  1.00 105.96 ? 191 HIS B ND1 1 
ATOM   5786  C CD2 . HIS B 1 191 ? 84.478  128.460 100.674 1.00 98.80  ? 191 HIS B CD2 1 
ATOM   5787  C CE1 . HIS B 1 191 ? 83.772  128.741 98.614  1.00 103.63 ? 191 HIS B CE1 1 
ATOM   5788  N NE2 . HIS B 1 191 ? 84.465  129.344 99.593  1.00 104.39 ? 191 HIS B NE2 1 
ATOM   5789  N N   . LEU B 1 192 ? 84.931  122.698 101.651 1.00 104.66 ? 192 LEU B N   1 
ATOM   5790  C CA  . LEU B 1 192 ? 84.971  121.546 102.561 1.00 99.15  ? 192 LEU B CA  1 
ATOM   5791  C C   . LEU B 1 192 ? 86.013  121.749 103.662 1.00 98.29  ? 192 LEU B C   1 
ATOM   5792  O O   . LEU B 1 192 ? 87.160  122.078 103.382 1.00 101.86 ? 192 LEU B O   1 
ATOM   5793  C CB  . LEU B 1 192 ? 85.300  120.268 101.769 1.00 99.90  ? 192 LEU B CB  1 
ATOM   5794  C CG  . LEU B 1 192 ? 84.217  119.859 100.771 1.00 103.85 ? 192 LEU B CG  1 
ATOM   5795  C CD1 . LEU B 1 192 ? 84.724  118.725 99.892  1.00 105.74 ? 192 LEU B CD1 1 
ATOM   5796  C CD2 . LEU B 1 192 ? 82.941  119.404 101.465 1.00 101.18 ? 192 LEU B CD2 1 
ATOM   5797  N N   . ARG B 1 193 ? 85.651  121.501 104.920 1.00 86.62  ? 193 ARG B N   1 
ATOM   5798  C CA  . ARG B 1 193 ? 86.545  121.677 106.069 1.00 87.74  ? 193 ARG B CA  1 
ATOM   5799  C C   . ARG B 1 193 ? 87.121  120.347 106.546 1.00 88.41  ? 193 ARG B C   1 
ATOM   5800  O O   . ARG B 1 193 ? 86.409  119.542 107.139 1.00 91.00  ? 193 ARG B O   1 
ATOM   5801  C CB  . ARG B 1 193 ? 85.819  122.473 107.155 1.00 88.57  ? 193 ARG B CB  1 
ATOM   5802  C CG  . ARG B 1 193 ? 85.761  123.964 106.865 1.00 91.53  ? 193 ARG B CG  1 
ATOM   5803  C CD  . ARG B 1 193 ? 84.422  124.609 107.144 1.00 91.76  ? 193 ARG B CD  1 
ATOM   5804  N NE  . ARG B 1 193 ? 84.066  124.545 108.550 1.00 98.65  ? 193 ARG B NE  1 
ATOM   5805  C CZ  . ARG B 1 193 ? 83.267  125.414 109.153 1.00 97.01  ? 193 ARG B CZ  1 
ATOM   5806  N NH1 . ARG B 1 193 ? 82.993  125.281 110.438 1.00 91.91  ? 193 ARG B NH1 1 
ATOM   5807  N NH2 . ARG B 1 193 ? 82.760  126.425 108.472 1.00 95.13  ? 193 ARG B NH2 1 
ATOM   5808  N N   . ALA B 1 194 ? 88.423  120.156 106.382 1.00 74.14  ? 194 ALA B N   1 
ATOM   5809  C CA  . ALA B 1 194 ? 89.176  119.080 107.008 1.00 72.72  ? 194 ALA B CA  1 
ATOM   5810  C C   . ALA B 1 194 ? 89.349  119.393 108.497 1.00 71.98  ? 194 ALA B C   1 
ATOM   5811  O O   . ALA B 1 194 ? 90.250  120.124 108.874 1.00 75.09  ? 194 ALA B O   1 
ATOM   5812  C CB  . ALA B 1 194 ? 90.511  118.958 106.277 1.00 76.24  ? 194 ALA B CB  1 
ATOM   5813  N N   . CYS B 1 195 ? 88.446  118.895 109.341 1.00 78.08  ? 195 CYS B N   1 
ATOM   5814  C CA  . CYS B 1 195 ? 88.229  119.390 110.704 1.00 79.85  ? 195 CYS B CA  1 
ATOM   5815  C C   . CYS B 1 195 ? 88.474  118.364 111.818 1.00 85.23  ? 195 CYS B C   1 
ATOM   5816  O O   . CYS B 1 195 ? 88.441  118.732 112.995 1.00 86.75  ? 195 CYS B O   1 
ATOM   5817  C CB  . CYS B 1 195 ? 86.811  119.970 110.782 1.00 83.99  ? 195 CYS B CB  1 
ATOM   5818  S SG  . CYS B 1 195 ? 85.552  118.788 110.223 1.00 87.60  ? 195 CYS B SG  1 
ATOM   5819  N N   . GLY B 1 196 ? 88.732  117.096 111.488 1.00 85.43  ? 196 GLY B N   1 
ATOM   5820  C CA  . GLY B 1 196 ? 89.095  116.059 112.454 1.00 79.17  ? 196 GLY B CA  1 
ATOM   5821  C C   . GLY B 1 196 ? 90.398  116.340 113.202 1.00 78.37  ? 196 GLY B C   1 
ATOM   5822  O O   . GLY B 1 196 ? 91.179  117.207 112.825 1.00 83.83  ? 196 GLY B O   1 
ATOM   5823  N N   . ARG B 1 197 ? 90.642  115.662 114.322 1.00 76.60  ? 197 ARG B N   1 
ATOM   5824  C CA  . ARG B 1 197 ? 91.769  115.991 115.248 1.00 77.20  ? 197 ARG B CA  1 
ATOM   5825  C C   . ARG B 1 197 ? 93.152  116.046 114.620 1.00 79.26  ? 197 ARG B C   1 
ATOM   5826  O O   . ARG B 1 197 ? 94.019  116.679 115.209 1.00 80.43  ? 197 ARG B O   1 
ATOM   5827  C CB  . ARG B 1 197 ? 91.806  114.984 116.396 1.00 77.59  ? 197 ARG B CB  1 
ATOM   5828  C CG  . ARG B 1 197 ? 92.650  115.408 117.587 1.00 81.56  ? 197 ARG B CG  1 
ATOM   5829  C CD  . ARG B 1 197 ? 91.815  116.105 118.639 1.00 80.78  ? 197 ARG B CD  1 
ATOM   5830  N NE  . ARG B 1 197 ? 92.162  117.512 118.746 1.00 87.10  ? 197 ARG B NE  1 
ATOM   5831  C CZ  . ARG B 1 197 ? 92.930  118.022 119.698 1.00 88.84  ? 197 ARG B CZ  1 
ATOM   5832  N NH1 . ARG B 1 197 ? 93.191  119.317 119.713 1.00 84.41  ? 197 ARG B NH1 1 
ATOM   5833  N NH2 . ARG B 1 197 ? 93.434  117.236 120.631 1.00 82.27  ? 197 ARG B NH2 1 
ATOM   5834  N N   . PHE B 1 198 ? 93.391  115.340 113.538 1.00 72.37  ? 198 PHE B N   1 
ATOM   5835  C CA  . PHE B 1 198 ? 94.690  115.480 112.881 1.00 72.09  ? 198 PHE B CA  1 
ATOM   5836  C C   . PHE B 1 198 ? 94.935  116.904 112.350 1.00 75.16  ? 198 PHE B C   1 
ATOM   5837  O O   . PHE B 1 198 ? 96.064  117.377 112.325 1.00 75.17  ? 198 PHE B O   1 
ATOM   5838  C CB  . PHE B 1 198 ? 94.774  114.448 111.756 1.00 68.52  ? 198 PHE B CB  1 
ATOM   5839  C CG  . PHE B 1 198 ? 96.044  114.537 110.948 1.00 72.76  ? 198 PHE B CG  1 
ATOM   5840  C CD1 . PHE B 1 198 ? 97.288  114.304 111.550 1.00 71.94  ? 198 PHE B CD1 1 
ATOM   5841  C CD2 . PHE B 1 198 ? 95.987  114.879 109.592 1.00 73.86  ? 198 PHE B CD2 1 
ATOM   5842  C CE1 . PHE B 1 198 ? 98.461  114.428 110.798 1.00 68.07  ? 198 PHE B CE1 1 
ATOM   5843  C CE2 . PHE B 1 198 ? 97.161  115.016 108.841 1.00 67.66  ? 198 PHE B CE2 1 
ATOM   5844  C CZ  . PHE B 1 198 ? 98.401  114.787 109.444 1.00 64.11  ? 198 PHE B CZ  1 
ATOM   5845  N N   . PHE B 1 199 ? 93.876  117.610 111.956 1.00 65.23  ? 199 PHE B N   1 
ATOM   5846  C CA  . PHE B 1 199 ? 93.930  118.945 111.366 1.00 59.33  ? 199 PHE B CA  1 
ATOM   5847  C C   . PHE B 1 199 ? 93.743  120.080 112.370 1.00 68.95  ? 199 PHE B C   1 
ATOM   5848  O O   . PHE B 1 199 ? 93.872  121.244 112.015 1.00 72.32  ? 199 PHE B O   1 
ATOM   5849  C CB  . PHE B 1 199 ? 92.855  119.037 110.296 1.00 62.27  ? 199 PHE B CB  1 
ATOM   5850  C CG  . PHE B 1 199 ? 92.926  117.919 109.293 1.00 65.12  ? 199 PHE B CG  1 
ATOM   5851  C CD1 . PHE B 1 199 ? 94.023  117.822 108.428 1.00 67.91  ? 199 PHE B CD1 1 
ATOM   5852  C CD2 . PHE B 1 199 ? 91.910  116.958 109.244 1.00 71.60  ? 199 PHE B CD2 1 
ATOM   5853  C CE1 . PHE B 1 199 ? 94.074  116.806 107.465 1.00 68.32  ? 199 PHE B CE1 1 
ATOM   5854  C CE2 . PHE B 1 199 ? 91.975  115.926 108.307 1.00 67.49  ? 199 PHE B CE2 1 
ATOM   5855  C CZ  . PHE B 1 199 ? 93.048  115.855 107.408 1.00 67.67  ? 199 PHE B CZ  1 
ATOM   5856  N N   . GLN B 1 200 ? 93.401  119.778 113.614 1.00 71.41  ? 200 GLN B N   1 
ATOM   5857  C CA  . GLN B 1 200 ? 93.340  120.746 114.700 1.00 66.74  ? 200 GLN B CA  1 
ATOM   5858  C C   . GLN B 1 200 ? 94.751  121.064 115.217 1.00 67.67  ? 200 GLN B C   1 
ATOM   5859  O O   . GLN B 1 200 ? 95.690  120.320 114.955 1.00 77.83  ? 200 GLN B O   1 
ATOM   5860  C CB  . GLN B 1 200 ? 92.417  120.193 115.790 1.00 72.76  ? 200 GLN B CB  1 
ATOM   5861  C CG  . GLN B 1 200 ? 90.978  120.017 115.268 1.00 77.16  ? 200 GLN B CG  1 
ATOM   5862  C CD  . GLN B 1 200 ? 90.053  119.341 116.266 1.00 76.01  ? 200 GLN B CD  1 
ATOM   5863  O OE1 . GLN B 1 200 ? 90.347  119.188 117.441 1.00 70.44  ? 200 GLN B OE1 1 
ATOM   5864  N NE2 . GLN B 1 200 ? 88.900  118.891 115.837 1.00 71.80  ? 200 GLN B NE2 1 
ATOM   5865  N N   . LYS B 1 201 ? 94.928  122.155 115.971 1.00 70.75  ? 201 LYS B N   1 
ATOM   5866  C CA  . LYS B 1 201 ? 96.227  122.523 116.552 1.00 74.95  ? 201 LYS B CA  1 
ATOM   5867  C C   . LYS B 1 201 ? 96.325  122.017 117.998 1.00 84.47  ? 201 LYS B C   1 
ATOM   5868  O O   . LYS B 1 201 ? 95.540  122.424 118.852 1.00 87.24  ? 201 LYS B O   1 
ATOM   5869  C CB  . LYS B 1 201 ? 96.404  124.044 116.437 1.00 79.85  ? 201 LYS B CB  1 
ATOM   5870  C CG  . LYS B 1 201 ? 97.826  124.494 116.787 1.00 81.24  ? 201 LYS B CG  1 
ATOM   5871  C CD  . LYS B 1 201 ? 97.948  126.017 116.763 1.00 83.23  ? 201 LYS B CD  1 
ATOM   5872  C CE  . LYS B 1 201 ? 99.334  126.446 117.253 1.00 82.05  ? 201 LYS B CE  1 
ATOM   5873  N NZ  . LYS B 1 201 ? 99.373  127.873 117.653 1.00 81.40  ? 201 LYS B NZ  1 
ATOM   5874  N N   . HIS B 1 202 ? 97.279  121.126 118.267 1.00 84.58  ? 202 HIS B N   1 
ATOM   5875  C CA  . HIS B 1 202 ? 97.537  120.499 119.570 1.00 77.58  ? 202 HIS B CA  1 
ATOM   5876  C C   . HIS B 1 202 ? 98.978  119.983 119.678 1.00 79.35  ? 202 HIS B C   1 
ATOM   5877  O O   . HIS B 1 202 ? 99.744  120.038 118.720 1.00 80.60  ? 202 HIS B O   1 
ATOM   5878  C CB  . HIS B 1 202 ? 96.501  119.401 119.841 1.00 78.58  ? 202 HIS B CB  1 
ATOM   5879  C CG  . HIS B 1 202 ? 96.504  118.248 118.878 1.00 82.19  ? 202 HIS B CG  1 
ATOM   5880  N ND1 . HIS B 1 202 ? 97.364  117.150 118.915 1.00 84.61  ? 202 HIS B ND1 1 
ATOM   5881  C CD2 . HIS B 1 202 ? 95.599  118.062 117.883 1.00 83.00  ? 202 HIS B CD2 1 
ATOM   5882  C CE1 . HIS B 1 202 ? 96.955  116.332 117.932 1.00 82.23  ? 202 HIS B CE1 1 
ATOM   5883  N NE2 . HIS B 1 202 ? 95.899  116.863 117.299 1.00 78.62  ? 202 HIS B NE2 1 
ATOM   5884  N N   . GLN B 1 203 ? 99.386  119.543 120.870 1.00 94.84  ? 203 GLN B N   1 
ATOM   5885  C CA  . GLN B 1 203 ? 100.756 119.118 121.170 1.00 98.01  ? 203 GLN B CA  1 
ATOM   5886  C C   . GLN B 1 203 ? 101.189 117.763 120.581 1.00 97.49  ? 203 GLN B C   1 
ATOM   5887  O O   . GLN B 1 203 ? 102.370 117.418 120.656 1.00 97.24  ? 203 GLN B O   1 
ATOM   5888  C CB  . GLN B 1 203 ? 100.895 119.085 122.690 1.00 91.59  ? 203 GLN B CB  1 
ATOM   5889  N N   . GLY B 1 204 ? 100.269 116.969 120.030 1.00 84.46  ? 204 GLY B N   1 
ATOM   5890  C CA  . GLY B 1 204 ? 100.533 115.663 119.422 1.00 84.08  ? 204 GLY B CA  1 
ATOM   5891  C C   . GLY B 1 204 ? 100.928 115.725 117.944 1.00 86.42  ? 204 GLY B C   1 
ATOM   5892  O O   . GLY B 1 204 ? 101.343 116.762 117.427 1.00 81.78  ? 204 GLY B O   1 
ATOM   5893  N N   . THR B 1 205 ? 100.724 114.609 117.247 1.00 87.90  ? 205 THR B N   1 
ATOM   5894  C CA  . THR B 1 205 ? 100.846 114.528 115.786 1.00 83.43  ? 205 THR B CA  1 
ATOM   5895  C C   . THR B 1 205 ? 99.656  115.213 115.124 1.00 87.97  ? 205 THR B C   1 
ATOM   5896  O O   . THR B 1 205 ? 98.532  114.722 115.193 1.00 85.36  ? 205 THR B O   1 
ATOM   5897  C CB  . THR B 1 205 ? 100.961 113.072 115.324 1.00 82.29  ? 205 THR B CB  1 
ATOM   5898  O OG1 . THR B 1 205 ? 102.114 112.501 115.884 1.00 82.33  ? 205 THR B OG1 1 
ATOM   5899  C CG2 . THR B 1 205 ? 101.107 112.938 113.818 1.00 81.23  ? 205 THR B CG2 1 
ATOM   5900  N N   . CYS B 1 206 ? 99.900  116.346 114.476 1.00 82.96  ? 206 CYS B N   1 
ATOM   5901  C CA  . CYS B 1 206 ? 98.895  117.129 113.768 1.00 74.51  ? 206 CYS B CA  1 
ATOM   5902  C C   . CYS B 1 206 ? 99.525  117.977 112.668 1.00 74.86  ? 206 CYS B C   1 
ATOM   5903  O O   . CYS B 1 206 ? 100.736 118.186 112.618 1.00 77.02  ? 206 CYS B O   1 
ATOM   5904  C CB  . CYS B 1 206 ? 98.126  118.024 114.749 1.00 71.17  ? 206 CYS B CB  1 
ATOM   5905  S SG  . CYS B 1 206 ? 99.141  119.386 115.370 1.00 62.37  ? 206 CYS B SG  1 
ATOM   5906  N N   . PHE B 1 207 ? 98.673  118.509 111.789 1.00 60.97  ? 207 PHE B N   1 
ATOM   5907  C CA  . PHE B 1 207 ? 99.002  119.463 110.729 1.00 47.18  ? 207 PHE B CA  1 
ATOM   5908  C C   . PHE B 1 207 ? 97.865  120.470 110.570 1.00 59.77  ? 207 PHE B C   1 
ATOM   5909  O O   . PHE B 1 207 ? 96.936  120.254 109.799 1.00 71.41  ? 207 PHE B O   1 
ATOM   5910  C CB  . PHE B 1 207 ? 99.280  118.706 109.425 1.00 55.46  ? 207 PHE B CB  1 
ATOM   5911  C CG  . PHE B 1 207 ? 99.484  119.549 108.173 1.00 60.39  ? 207 PHE B CG  1 
ATOM   5912  C CD1 . PHE B 1 207 ? 100.344 120.660 108.167 1.00 62.12  ? 207 PHE B CD1 1 
ATOM   5913  C CD2 . PHE B 1 207 ? 98.840  119.178 106.986 1.00 63.13  ? 207 PHE B CD2 1 
ATOM   5914  C CE1 . PHE B 1 207 ? 100.570 121.374 106.980 1.00 58.47  ? 207 PHE B CE1 1 
ATOM   5915  C CE2 . PHE B 1 207 ? 99.072  119.884 105.794 1.00 59.27  ? 207 PHE B CE2 1 
ATOM   5916  C CZ  . PHE B 1 207 ? 99.938  120.983 105.792 1.00 58.81  ? 207 PHE B CZ  1 
ATOM   5917  N N   . TYR B 1 208 ? 97.912  121.571 111.318 1.00 68.57  ? 208 TYR B N   1 
ATOM   5918  C CA  . TYR B 1 208 ? 96.990  122.689 111.143 1.00 66.68  ? 208 TYR B CA  1 
ATOM   5919  C C   . TYR B 1 208 ? 97.388  123.528 109.922 1.00 76.81  ? 208 TYR B C   1 
ATOM   5920  O O   . TYR B 1 208 ? 98.523  123.984 109.819 1.00 80.21  ? 208 TYR B O   1 
ATOM   5921  C CB  . TYR B 1 208 ? 96.946  123.534 112.422 1.00 63.93  ? 208 TYR B CB  1 
ATOM   5922  C CG  . TYR B 1 208 ? 95.964  124.686 112.362 1.00 67.40  ? 208 TYR B CG  1 
ATOM   5923  C CD1 . TYR B 1 208 ? 94.597  124.456 112.596 1.00 70.41  ? 208 TYR B CD1 1 
ATOM   5924  C CD2 . TYR B 1 208 ? 96.403  125.980 112.028 1.00 71.99  ? 208 TYR B CD2 1 
ATOM   5925  C CE1 . TYR B 1 208 ? 93.663  125.496 112.463 1.00 61.66  ? 208 TYR B CE1 1 
ATOM   5926  C CE2 . TYR B 1 208 ? 95.473  127.024 111.893 1.00 72.05  ? 208 TYR B CE2 1 
ATOM   5927  C CZ  . TYR B 1 208 ? 94.102  126.780 112.096 1.00 67.56  ? 208 TYR B CZ  1 
ATOM   5928  O OH  . TYR B 1 208 ? 93.208  127.777 111.904 1.00 76.90  ? 208 TYR B OH  1 
ATOM   5929  N N   . PHE B 1 209 ? 96.444  123.772 109.015 1.00 67.38  ? 209 PHE B N   1 
ATOM   5930  C CA  . PHE B 1 209 ? 96.589  124.622 107.830 1.00 60.55  ? 209 PHE B CA  1 
ATOM   5931  C C   . PHE B 1 209 ? 95.400  125.577 107.690 1.00 65.32  ? 209 PHE B C   1 
ATOM   5932  O O   . PHE B 1 209 ? 95.091  126.045 106.598 1.00 80.10  ? 209 PHE B O   1 
ATOM   5933  C CB  . PHE B 1 209 ? 96.812  123.752 106.587 1.00 64.60  ? 209 PHE B CB  1 
ATOM   5934  C CG  . PHE B 1 209 ? 95.753  122.703 106.316 1.00 61.99  ? 209 PHE B CG  1 
ATOM   5935  C CD1 . PHE B 1 209 ? 94.525  123.033 105.719 1.00 65.75  ? 209 PHE B CD1 1 
ATOM   5936  C CD2 . PHE B 1 209 ? 96.017  121.366 106.637 1.00 60.83  ? 209 PHE B CD2 1 
ATOM   5937  C CE1 . PHE B 1 209 ? 93.575  122.038 105.443 1.00 64.16  ? 209 PHE B CE1 1 
ATOM   5938  C CE2 . PHE B 1 209 ? 95.089  120.369 106.326 1.00 68.56  ? 209 PHE B CE2 1 
ATOM   5939  C CZ  . PHE B 1 209 ? 93.865  120.702 105.734 1.00 66.38  ? 209 PHE B CZ  1 
ATOM   5940  N N   . GLY B 1 210 ? 94.687  125.861 108.774 1.00 65.64  ? 210 GLY B N   1 
ATOM   5941  C CA  . GLY B 1 210 ? 93.271  126.201 108.681 1.00 63.66  ? 210 GLY B CA  1 
ATOM   5942  C C   . GLY B 1 210 ? 92.501  124.891 108.504 1.00 75.75  ? 210 GLY B C   1 
ATOM   5943  O O   . GLY B 1 210 ? 92.964  123.845 108.952 1.00 85.30  ? 210 GLY B O   1 
ATOM   5944  N N   . GLU B 1 211 ? 91.369  124.898 107.807 1.00 73.21  ? 211 GLU B N   1 
ATOM   5945  C CA  . GLU B 1 211 ? 90.662  123.652 107.445 1.00 73.08  ? 211 GLU B CA  1 
ATOM   5946  C C   . GLU B 1 211 ? 90.247  123.580 105.974 1.00 76.25  ? 211 GLU B C   1 
ATOM   5947  O O   . GLU B 1 211 ? 89.782  122.547 105.504 1.00 89.32  ? 211 GLU B O   1 
ATOM   5948  C CB  . GLU B 1 211 ? 89.433  123.466 108.338 1.00 76.05  ? 211 GLU B CB  1 
ATOM   5949  C CG  . GLU B 1 211 ? 89.791  123.275 109.817 1.00 75.41  ? 211 GLU B CG  1 
ATOM   5950  C CD  . GLU B 1 211 ? 88.564  123.209 110.732 1.00 85.16  ? 211 GLU B CD  1 
ATOM   5951  O OE1 . GLU B 1 211 ? 87.408  123.435 110.289 1.00 82.67  ? 211 GLU B OE1 1 
ATOM   5952  O OE2 . GLU B 1 211 ? 88.771  123.006 111.945 1.00 85.92  ? 211 GLU B OE2 1 
ATOM   5953  N N   . LEU B 1 212 ? 90.385  124.671 105.232 1.00 70.83  ? 212 LEU B N   1 
ATOM   5954  C CA  . LEU B 1 212 ? 89.834  124.828 103.889 1.00 74.21  ? 212 LEU B CA  1 
ATOM   5955  C C   . LEU B 1 212 ? 90.900  124.589 102.815 1.00 71.56  ? 212 LEU B C   1 
ATOM   5956  O O   . LEU B 1 212 ? 92.069  124.900 103.046 1.00 71.84  ? 212 LEU B O   1 
ATOM   5957  C CB  . LEU B 1 212 ? 89.245  126.239 103.758 1.00 79.35  ? 212 LEU B CB  1 
ATOM   5958  C CG  . LEU B 1 212 ? 88.070  126.537 104.700 1.00 74.74  ? 212 LEU B CG  1 
ATOM   5959  C CD1 . LEU B 1 212 ? 87.905  128.036 104.842 1.00 74.50  ? 212 LEU B CD1 1 
ATOM   5960  C CD2 . LEU B 1 212 ? 86.773  125.968 104.157 1.00 72.20  ? 212 LEU B CD2 1 
ATOM   5961  N N   . PRO B 1 213 ? 90.510  124.141 101.612 1.00 76.65  ? 213 PRO B N   1 
ATOM   5962  C CA  . PRO B 1 213 ? 91.363  124.091 100.430 1.00 82.91  ? 213 PRO B CA  1 
ATOM   5963  C C   . PRO B 1 213 ? 92.176  125.364 100.172 1.00 82.76  ? 213 PRO B C   1 
ATOM   5964  O O   . PRO B 1 213 ? 93.376  125.280 99.943  1.00 83.45  ? 213 PRO B O   1 
ATOM   5965  C CB  . PRO B 1 213 ? 90.396  123.798 99.283  1.00 82.79  ? 213 PRO B CB  1 
ATOM   5966  C CG  . PRO B 1 213 ? 89.364  122.899 99.938  1.00 78.44  ? 213 PRO B CG  1 
ATOM   5967  C CD  . PRO B 1 213 ? 89.229  123.529 101.315 1.00 77.28  ? 213 PRO B CD  1 
ATOM   5968  N N   . LEU B 1 214 ? 91.585  126.560 100.264 1.00 78.27  ? 214 LEU B N   1 
ATOM   5969  C CA  . LEU B 1 214 ? 92.325  127.810 100.055 1.00 79.43  ? 214 LEU B CA  1 
ATOM   5970  C C   . LEU B 1 214 ? 93.408  128.046 101.118 1.00 80.30  ? 214 LEU B C   1 
ATOM   5971  O O   . LEU B 1 214 ? 94.514  128.475 100.796 1.00 84.17  ? 214 LEU B O   1 
ATOM   5972  C CB  . LEU B 1 214 ? 91.336  128.983 99.994  1.00 77.12  ? 214 LEU B CB  1 
ATOM   5973  C CG  . LEU B 1 214 ? 92.014  130.354 99.810  1.00 79.96  ? 214 LEU B CG  1 
ATOM   5974  C CD1 . LEU B 1 214 ? 92.758  130.461 98.487  1.00 78.42  ? 214 LEU B CD1 1 
ATOM   5975  C CD2 . LEU B 1 214 ? 90.979  131.464 99.879  1.00 85.25  ? 214 LEU B CD2 1 
ATOM   5976  N N   . SER B 1 215 ? 93.118  127.740 102.380 1.00 63.13  ? 215 SER B N   1 
ATOM   5977  C CA  . SER B 1 215 ? 94.093  127.875 103.460 1.00 56.65  ? 215 SER B CA  1 
ATOM   5978  C C   . SER B 1 215 ? 95.211  126.840 103.354 1.00 65.11  ? 215 SER B C   1 
ATOM   5979  O O   . SER B 1 215 ? 96.370  127.172 103.576 1.00 69.89  ? 215 SER B O   1 
ATOM   5980  C CB  . SER B 1 215 ? 93.414  127.786 104.819 1.00 61.77  ? 215 SER B CB  1 
ATOM   5981  O OG  . SER B 1 215 ? 92.269  128.616 104.854 1.00 66.05  ? 215 SER B OG  1 
ATOM   5982  N N   . LEU B 1 216 ? 94.918  125.614 102.914 1.00 72.30  ? 216 LEU B N   1 
ATOM   5983  C CA  . LEU B 1 216 ? 95.932  124.612 102.591 1.00 70.80  ? 216 LEU B CA  1 
ATOM   5984  C C   . LEU B 1 216 ? 96.850  125.078 101.460 1.00 70.71  ? 216 LEU B C   1 
ATOM   5985  O O   . LEU B 1 216 ? 98.069  125.003 101.584 1.00 76.10  ? 216 LEU B O   1 
ATOM   5986  C CB  . LEU B 1 216 ? 95.232  123.290 102.242 1.00 68.23  ? 216 LEU B CB  1 
ATOM   5987  C CG  . LEU B 1 216 ? 96.171  122.124 101.901 1.00 62.23  ? 216 LEU B CG  1 
ATOM   5988  C CD1 . LEU B 1 216 ? 97.191  121.785 102.977 1.00 65.90  ? 216 LEU B CD1 1 
ATOM   5989  C CD2 . LEU B 1 216 ? 95.327  120.886 101.666 1.00 65.56  ? 216 LEU B CD2 1 
ATOM   5990  N N   . ALA B 1 217 ? 96.296  125.594 100.364 1.00 65.83  ? 217 ALA B N   1 
ATOM   5991  C CA  . ALA B 1 217 ? 97.071  126.091 99.234  1.00 56.94  ? 217 ALA B CA  1 
ATOM   5992  C C   . ALA B 1 217 ? 97.990  127.262 99.622  1.00 65.96  ? 217 ALA B C   1 
ATOM   5993  O O   . ALA B 1 217 ? 99.146  127.305 99.214  1.00 67.55  ? 217 ALA B O   1 
ATOM   5994  C CB  . ALA B 1 217 ? 96.093  126.469 98.122  1.00 59.69  ? 217 ALA B CB  1 
ATOM   5995  N N   . ALA B 1 218 ? 97.521  128.178 100.470 1.00 76.50  ? 218 ALA B N   1 
ATOM   5996  C CA  . ALA B 1 218 ? 98.338  129.253 101.023 1.00 66.26  ? 218 ALA B CA  1 
ATOM   5997  C C   . ALA B 1 218 ? 99.458  128.728 101.938 1.00 65.51  ? 218 ALA B C   1 
ATOM   5998  O O   . ALA B 1 218 ? 100.618 129.088 101.772 1.00 68.17  ? 218 ALA B O   1 
ATOM   5999  C CB  . ALA B 1 218 ? 97.410  130.221 101.758 1.00 58.56  ? 218 ALA B CB  1 
ATOM   6000  N N   . CYS B 1 219 ? 99.166  127.832 102.877 1.00 79.47  ? 219 CYS B N   1 
ATOM   6001  C CA  . CYS B 1 219 ? 100.163 127.346 103.834 1.00 81.32  ? 219 CYS B CA  1 
ATOM   6002  C C   . CYS B 1 219 ? 101.228 126.427 103.206 1.00 78.10  ? 219 CYS B C   1 
ATOM   6003  O O   . CYS B 1 219 ? 102.382 126.435 103.621 1.00 71.56  ? 219 CYS B O   1 
ATOM   6004  C CB  . CYS B 1 219 ? 99.426  126.683 104.996 1.00 79.96  ? 219 CYS B CB  1 
ATOM   6005  S SG  . CYS B 1 219 ? 98.354  127.922 105.771 1.00 86.37  ? 219 CYS B SG  1 
ATOM   6006  N N   . THR B 1 220 ? 100.872 125.692 102.151 1.00 82.77  ? 220 THR B N   1 
ATOM   6007  C CA  . THR B 1 220 ? 101.796 124.937 101.285 1.00 79.27  ? 220 THR B CA  1 
ATOM   6008  C C   . THR B 1 220 ? 102.474 125.801 100.205 1.00 81.98  ? 220 THR B C   1 
ATOM   6009  O O   . THR B 1 220 ? 103.255 125.279 99.412  1.00 87.06  ? 220 THR B O   1 
ATOM   6010  C CB  . THR B 1 220 ? 101.086 123.750 100.629 1.00 78.29  ? 220 THR B CB  1 
ATOM   6011  O OG1 . THR B 1 220 ? 99.982  124.191 99.893  1.00 86.61  ? 220 THR B OG1 1 
ATOM   6012  C CG2 . THR B 1 220 ? 100.550 122.723 101.610 1.00 75.83  ? 220 THR B CG2 1 
ATOM   6013  N N   . LYS B 1 221 ? 102.244 127.121 100.185 1.00 81.99  ? 221 LYS B N   1 
ATOM   6014  C CA  . LYS B 1 221 ? 102.939 128.122 99.353  1.00 77.90  ? 221 LYS B CA  1 
ATOM   6015  C C   . LYS B 1 221 ? 102.711 127.991 97.848  1.00 82.40  ? 221 LYS B C   1 
ATOM   6016  O O   . LYS B 1 221 ? 103.641 128.126 97.059  1.00 82.24  ? 221 LYS B O   1 
ATOM   6017  C CB  . LYS B 1 221 ? 104.431 128.220 99.720  1.00 75.26  ? 221 LYS B CB  1 
ATOM   6018  C CG  . LYS B 1 221 ? 104.691 128.221 101.230 1.00 85.62  ? 221 LYS B CG  1 
ATOM   6019  C CD  . LYS B 1 221 ? 106.153 128.555 101.534 1.00 88.13  ? 221 LYS B CD  1 
ATOM   6020  C CE  . LYS B 1 221 ? 106.575 128.165 102.954 1.00 85.75  ? 221 LYS B CE  1 
ATOM   6021  N NZ  . LYS B 1 221 ? 105.668 128.674 104.014 1.00 78.73  ? 221 LYS B NZ  1 
ATOM   6022  N N   . GLN B 1 222 ? 101.484 127.694 97.429  1.00 89.99  ? 222 GLN B N   1 
ATOM   6023  C CA  . GLN B 1 222 ? 101.140 127.420 96.032  1.00 88.80  ? 222 GLN B CA  1 
ATOM   6024  C C   . GLN B 1 222 ? 100.392 128.585 95.378  1.00 83.80  ? 222 GLN B C   1 
ATOM   6025  O O   . GLN B 1 222 ? 99.168  128.581 95.317  1.00 82.58  ? 222 GLN B O   1 
ATOM   6026  C CB  . GLN B 1 222 ? 100.328 126.125 95.959  1.00 87.15  ? 222 GLN B CB  1 
ATOM   6027  C CG  . GLN B 1 222 ? 101.135 124.932 96.459  1.00 83.35  ? 222 GLN B CG  1 
ATOM   6028  C CD  . GLN B 1 222 ? 100.374 123.645 96.250  1.00 84.88  ? 222 GLN B CD  1 
ATOM   6029  O OE1 . GLN B 1 222 ? 100.233 123.158 95.145  1.00 93.37  ? 222 GLN B OE1 1 
ATOM   6030  N NE2 . GLN B 1 222 ? 99.864  123.051 97.298  1.00 84.40  ? 222 GLN B NE2 1 
ATOM   6031  N N   . TRP B 1 223 ? 101.101 129.582 94.886  1.00 88.66  ? 223 TRP B N   1 
ATOM   6032  C CA  . TRP B 1 223 ? 100.327 130.713 94.336  1.00 96.10  ? 223 TRP B CA  1 
ATOM   6033  C C   . TRP B 1 223 ? 99.403  130.216 93.221  1.00 100.91 ? 223 TRP B C   1 
ATOM   6034  O O   . TRP B 1 223 ? 98.217  130.523 93.294  1.00 104.35 ? 223 TRP B O   1 
ATOM   6035  C CB  . TRP B 1 223 ? 101.264 131.828 93.876  1.00 95.88  ? 223 TRP B CB  1 
ATOM   6036  C CG  . TRP B 1 223 ? 101.748 132.696 94.992  1.00 101.37 ? 223 TRP B CG  1 
ATOM   6037  C CD1 . TRP B 1 223 ? 103.005 132.739 95.520  1.00 99.58  ? 223 TRP B CD1 1 
ATOM   6038  C CD2 . TRP B 1 223 ? 100.971 133.654 95.728  1.00 101.45 ? 223 TRP B CD2 1 
ATOM   6039  N NE1 . TRP B 1 223 ? 103.066 133.661 96.531  1.00 95.37  ? 223 TRP B NE1 1 
ATOM   6040  C CE2 . TRP B 1 223 ? 101.832 134.236 96.681  1.00 100.80 ? 223 TRP B CE2 1 
ATOM   6041  C CE3 . TRP B 1 223 ? 99.640  134.075 95.672  1.00 92.48  ? 223 TRP B CE3 1 
ATOM   6042  C CZ2 . TRP B 1 223 ? 101.401 135.218 97.567  1.00 100.23 ? 223 TRP B CZ2 1 
ATOM   6043  C CZ3 . TRP B 1 223 ? 99.217  135.040 96.554  1.00 89.91  ? 223 TRP B CZ3 1 
ATOM   6044  C CH2 . TRP B 1 223 ? 100.084 135.600 97.487  1.00 97.43  ? 223 TRP B CH2 1 
ATOM   6045  N N   . ASP B 1 224 ? 99.903  129.466 92.240  1.00 102.49 ? 224 ASP B N   1 
ATOM   6046  C CA  . ASP B 1 224 ? 99.091  129.061 91.094  1.00 98.87  ? 224 ASP B CA  1 
ATOM   6047  C C   . ASP B 1 224 ? 97.794  128.359 91.522  1.00 100.19 ? 224 ASP B C   1 
ATOM   6048  O O   . ASP B 1 224 ? 96.728  128.672 90.996  1.00 98.08  ? 224 ASP B O   1 
ATOM   6049  C CB  . ASP B 1 224 ? 99.923  128.205 90.125  1.00 101.23 ? 224 ASP B CB  1 
ATOM   6050  C CG  . ASP B 1 224 ? 100.669 127.001 90.724  1.00 102.97 ? 224 ASP B CG  1 
ATOM   6051  O OD1 . ASP B 1 224 ? 100.651 126.810 91.958  1.00 101.21 ? 224 ASP B OD1 1 
ATOM   6052  O OD2 . ASP B 1 224 ? 101.307 126.267 89.943  1.00 105.91 ? 224 ASP B OD2 1 
ATOM   6053  N N   . VAL B 1 225 ? 97.852  127.477 92.519  1.00 97.07  ? 225 VAL B N   1 
ATOM   6054  C CA  . VAL B 1 225 ? 96.660  126.860 93.119  1.00 94.41  ? 225 VAL B CA  1 
ATOM   6055  C C   . VAL B 1 225 ? 95.826  127.890 93.875  1.00 93.37  ? 225 VAL B C   1 
ATOM   6056  O O   . VAL B 1 225 ? 94.612  127.901 93.717  1.00 98.40  ? 225 VAL B O   1 
ATOM   6057  C CB  . VAL B 1 225 ? 97.022  125.673 94.027  1.00 95.55  ? 225 VAL B CB  1 
ATOM   6058  C CG1 . VAL B 1 225 ? 95.780  125.033 94.644  1.00 94.92  ? 225 VAL B CG1 1 
ATOM   6059  C CG2 . VAL B 1 225 ? 97.746  124.575 93.247  1.00 91.91  ? 225 VAL B CG2 1 
ATOM   6060  N N   . VAL B 1 226 ? 96.434  128.794 94.648  1.00 89.11  ? 226 VAL B N   1 
ATOM   6061  C CA  . VAL B 1 226 ? 95.724  129.884 95.347  1.00 91.23  ? 226 VAL B CA  1 
ATOM   6062  C C   . VAL B 1 226 ? 94.998  130.780 94.351  1.00 93.98  ? 226 VAL B C   1 
ATOM   6063  O O   . VAL B 1 226 ? 93.814  131.038 94.520  1.00 93.45  ? 226 VAL B O   1 
ATOM   6064  C CB  . VAL B 1 226 ? 96.695  130.709 96.211  1.00 90.72  ? 226 VAL B CB  1 
ATOM   6065  C CG1 . VAL B 1 226 ? 96.136  132.059 96.655  1.00 91.00  ? 226 VAL B CG1 1 
ATOM   6066  C CG2 . VAL B 1 226 ? 97.059  129.937 97.477  1.00 94.22  ? 226 VAL B CG2 1 
ATOM   6067  N N   . THR B 1 227 ? 95.672  131.195 93.278  1.00 102.83 ? 227 THR B N   1 
ATOM   6068  C CA  . THR B 1 227 ? 95.057  131.967 92.197  1.00 98.87  ? 227 THR B CA  1 
ATOM   6069  C C   . THR B 1 227 ? 93.908  131.186 91.567  1.00 96.43  ? 227 THR B C   1 
ATOM   6070  O O   . THR B 1 227 ? 92.813  131.716 91.421  1.00 95.56  ? 227 THR B O   1 
ATOM   6071  C CB  . THR B 1 227 ? 96.089  132.324 91.117  1.00 95.88  ? 227 THR B CB  1 
ATOM   6072  O OG1 . THR B 1 227 ? 97.162  133.038 91.677  1.00 95.91  ? 227 THR B OG1 1 
ATOM   6073  C CG2 . THR B 1 227 ? 95.498  133.187 90.011  1.00 93.62  ? 227 THR B CG2 1 
ATOM   6074  N N   . TYR B 1 228 ? 94.102  129.907 91.237  1.00 97.65  ? 228 TYR B N   1 
ATOM   6075  C CA  . TYR B 1 228 ? 93.035  129.113 90.643  1.00 98.45  ? 228 TYR B CA  1 
ATOM   6076  C C   . TYR B 1 228 ? 91.829  128.977 91.583  1.00 100.56 ? 228 TYR B C   1 
ATOM   6077  O O   . TYR B 1 228 ? 90.702  129.284 91.201  1.00 103.20 ? 228 TYR B O   1 
ATOM   6078  C CB  . TYR B 1 228 ? 93.577  127.754 90.204  1.00 98.98  ? 228 TYR B CB  1 
ATOM   6079  C CG  . TYR B 1 228 ? 92.512  126.961 89.489  1.00 99.66  ? 228 TYR B CG  1 
ATOM   6080  C CD1 . TYR B 1 228 ? 92.181  127.296 88.164  1.00 99.87  ? 228 TYR B CD1 1 
ATOM   6081  C CD2 . TYR B 1 228 ? 91.748  126.013 90.188  1.00 96.13  ? 228 TYR B CD2 1 
ATOM   6082  C CE1 . TYR B 1 228 ? 91.071  126.704 87.543  1.00 98.83  ? 228 TYR B CE1 1 
ATOM   6083  C CE2 . TYR B 1 228 ? 90.635  125.420 89.571  1.00 100.68 ? 228 TYR B CE2 1 
ATOM   6084  C CZ  . TYR B 1 228 ? 90.291  125.768 88.252  1.00 102.77 ? 228 TYR B CZ  1 
ATOM   6085  O OH  . TYR B 1 228 ? 89.210  125.205 87.660  1.00 102.45 ? 228 TYR B OH  1 
ATOM   6086  N N   . LEU B 1 229 ? 92.035  128.588 92.840  1.00 95.55  ? 229 LEU B N   1 
ATOM   6087  C CA  . LEU B 1 229 ? 90.943  128.471 93.802  1.00 95.14  ? 229 LEU B CA  1 
ATOM   6088  C C   . LEU B 1 229 ? 90.210  129.803 93.976  1.00 97.35  ? 229 LEU B C   1 
ATOM   6089  O O   . LEU B 1 229 ? 88.985  129.801 93.994  1.00 94.28  ? 229 LEU B O   1 
ATOM   6090  C CB  . LEU B 1 229 ? 91.479  127.948 95.143  1.00 94.99  ? 229 LEU B CB  1 
ATOM   6091  C CG  . LEU B 1 229 ? 91.919  126.477 95.134  1.00 90.89  ? 229 LEU B CG  1 
ATOM   6092  C CD1 . LEU B 1 229 ? 92.534  126.147 96.484  1.00 90.30  ? 229 LEU B CD1 1 
ATOM   6093  C CD2 . LEU B 1 229 ? 90.766  125.510 94.903  1.00 90.27  ? 229 LEU B CD2 1 
ATOM   6094  N N   . LEU B 1 230 ? 90.915  130.936 94.046  1.00 100.46 ? 230 LEU B N   1 
ATOM   6095  C CA  . LEU B 1 230 ? 90.309  132.260 94.217  1.00 95.50  ? 230 LEU B CA  1 
ATOM   6096  C C   . LEU B 1 230 ? 89.510  132.765 93.016  1.00 96.09  ? 230 LEU B C   1 
ATOM   6097  O O   . LEU B 1 230 ? 88.496  133.426 93.221  1.00 91.65  ? 230 LEU B O   1 
ATOM   6098  C CB  . LEU B 1 230 ? 91.404  133.288 94.526  1.00 91.60  ? 230 LEU B CB  1 
ATOM   6099  C CG  . LEU B 1 230 ? 91.905  133.256 95.970  1.00 90.37  ? 230 LEU B CG  1 
ATOM   6100  C CD1 . LEU B 1 230 ? 93.058  134.238 96.142  1.00 93.64  ? 230 LEU B CD1 1 
ATOM   6101  C CD2 . LEU B 1 230 ? 90.823  133.666 96.952  1.00 89.07  ? 230 LEU B CD2 1 
ATOM   6102  N N   . GLU B 1 231 ? 89.947  132.509 91.779  1.00 109.66 ? 231 GLU B N   1 
ATOM   6103  C CA  . GLU B 1 231 ? 89.363  133.152 90.591  1.00 107.89 ? 231 GLU B CA  1 
ATOM   6104  C C   . GLU B 1 231 ? 89.025  132.215 89.409  1.00 108.07 ? 231 GLU B C   1 
ATOM   6105  O O   . GLU B 1 231 ? 88.817  132.679 88.291  1.00 112.19 ? 231 GLU B O   1 
ATOM   6106  C CB  . GLU B 1 231 ? 90.142  134.436 90.228  1.00 108.80 ? 231 GLU B CB  1 
ATOM   6107  C CG  . GLU B 1 231 ? 91.642  134.256 89.974  1.00 108.57 ? 231 GLU B CG  1 
ATOM   6108  C CD  . GLU B 1 231 ? 92.298  135.537 89.436  1.00 110.65 ? 231 GLU B CD  1 
ATOM   6109  O OE1 . GLU B 1 231 ? 92.291  136.581 90.130  1.00 110.74 ? 231 GLU B OE1 1 
ATOM   6110  O OE2 . GLU B 1 231 ? 92.846  135.501 88.311  1.00 108.37 ? 231 GLU B OE2 1 
ATOM   6111  N N   . ASN B 1 232 ? 88.882  130.905 89.636  1.00 108.03 ? 232 ASN B N   1 
ATOM   6112  C CA  . ASN B 1 232 ? 88.205  130.008 88.690  1.00 110.37 ? 232 ASN B CA  1 
ATOM   6113  C C   . ASN B 1 232 ? 86.702  130.354 88.536  1.00 113.30 ? 232 ASN B C   1 
ATOM   6114  O O   . ASN B 1 232 ? 86.090  130.866 89.478  1.00 113.21 ? 232 ASN B O   1 
ATOM   6115  C CB  . ASN B 1 232 ? 88.389  128.537 89.110  1.00 111.34 ? 232 ASN B CB  1 
ATOM   6116  C CG  . ASN B 1 232 ? 87.499  128.130 90.271  1.00 108.53 ? 232 ASN B CG  1 
ATOM   6117  O OD1 . ASN B 1 232 ? 86.373  127.707 90.074  1.00 107.48 ? 232 ASN B OD1 1 
ATOM   6118  N ND2 . ASN B 1 232 ? 87.955  128.254 91.488  1.00 107.06 ? 232 ASN B ND2 1 
ATOM   6119  N N   . PRO B 1 233 ? 86.068  130.057 87.385  1.00 117.97 ? 233 PRO B N   1 
ATOM   6120  C CA  . PRO B 1 233 ? 84.659  130.378 87.146  1.00 117.40 ? 233 PRO B CA  1 
ATOM   6121  C C   . PRO B 1 233 ? 83.658  129.365 87.733  1.00 117.22 ? 233 PRO B C   1 
ATOM   6122  O O   . PRO B 1 233 ? 82.458  129.637 87.734  1.00 115.05 ? 233 PRO B O   1 
ATOM   6123  C CB  . PRO B 1 233 ? 84.545  130.437 85.622  1.00 114.29 ? 233 PRO B CB  1 
ATOM   6124  C CG  . PRO B 1 233 ? 85.555  129.394 85.159  1.00 114.59 ? 233 PRO B CG  1 
ATOM   6125  C CD  . PRO B 1 233 ? 86.689  129.560 86.167  1.00 114.98 ? 233 PRO B CD  1 
ATOM   6126  N N   . HIS B 1 234 ? 84.106  128.192 88.189  1.00 118.20 ? 234 HIS B N   1 
ATOM   6127  C CA  . HIS B 1 234 ? 83.229  127.089 88.616  1.00 118.76 ? 234 HIS B CA  1 
ATOM   6128  C C   . HIS B 1 234 ? 82.727  127.267 90.050  1.00 121.25 ? 234 HIS B C   1 
ATOM   6129  O O   . HIS B 1 234 ? 81.525  127.245 90.300  1.00 120.06 ? 234 HIS B O   1 
ATOM   6130  C CB  . HIS B 1 234 ? 83.962  125.749 88.450  1.00 117.31 ? 234 HIS B CB  1 
ATOM   6131  C CG  . HIS B 1 234 ? 84.542  125.557 87.074  1.00 116.42 ? 234 HIS B CG  1 
ATOM   6132  N ND1 . HIS B 1 234 ? 83.805  125.365 85.905  1.00 117.99 ? 234 HIS B ND1 1 
ATOM   6133  C CD2 . HIS B 1 234 ? 85.867  125.605 86.760  1.00 116.94 ? 234 HIS B CD2 1 
ATOM   6134  C CE1 . HIS B 1 234 ? 84.707  125.303 84.914  1.00 120.01 ? 234 HIS B CE1 1 
ATOM   6135  N NE2 . HIS B 1 234 ? 85.950  125.449 85.396  1.00 119.63 ? 234 HIS B NE2 1 
ATOM   6136  N N   . GLN B 1 235 ? 83.684  127.564 90.938  1.00 119.94 ? 235 GLN B N   1 
ATOM   6137  C CA  . GLN B 1 235 ? 83.375  127.834 92.362  1.00 116.37 ? 235 GLN B CA  1 
ATOM   6138  C C   . GLN B 1 235 ? 84.572  128.605 92.929  1.00 119.53 ? 235 GLN B C   1 
ATOM   6139  O O   . GLN B 1 235 ? 85.570  127.948 93.264  1.00 117.29 ? 235 GLN B O   1 
ATOM   6140  C CB  . GLN B 1 235 ? 83.157  126.530 93.124  1.00 115.66 ? 235 GLN B CB  1 
ATOM   6141  C CG  . GLN B 1 235 ? 83.133  126.713 94.634  1.00 120.55 ? 235 GLN B CG  1 
ATOM   6142  C CD  . GLN B 1 235 ? 82.566  125.517 95.357  1.00 120.68 ? 235 GLN B CD  1 
ATOM   6143  O OE1 . GLN B 1 235 ? 82.312  124.472 94.764  1.00 116.82 ? 235 GLN B OE1 1 
ATOM   6144  N NE2 . GLN B 1 235 ? 82.362  125.667 96.655  1.00 118.62 ? 235 GLN B NE2 1 
ATOM   6145  N N   . PRO B 1 236 ? 84.556  129.959 92.984  1.00 117.84 ? 236 PRO B N   1 
ATOM   6146  C CA  . PRO B 1 236 ? 85.635  130.737 93.571  1.00 115.34 ? 236 PRO B CA  1 
ATOM   6147  C C   . PRO B 1 236 ? 85.651  130.568 95.096  1.00 111.69 ? 236 PRO B C   1 
ATOM   6148  O O   . PRO B 1 236 ? 84.612  130.629 95.754  1.00 109.82 ? 236 PRO B O   1 
ATOM   6149  C CB  . PRO B 1 236 ? 85.374  132.176 93.130  1.00 110.66 ? 236 PRO B CB  1 
ATOM   6150  C CG  . PRO B 1 236 ? 83.865  132.233 92.932  1.00 109.75 ? 236 PRO B CG  1 
ATOM   6151  C CD  . PRO B 1 236 ? 83.508  130.825 92.473  1.00 111.32 ? 236 PRO B CD  1 
ATOM   6152  N N   . ALA B 1 237 ? 86.835  130.359 95.662  1.00 104.22 ? 237 ALA B N   1 
ATOM   6153  C CA  . ALA B 1 237 ? 87.060  130.333 97.093  1.00 102.71 ? 237 ALA B CA  1 
ATOM   6154  C C   . ALA B 1 237 ? 86.765  131.710 97.694  1.00 107.33 ? 237 ALA B C   1 
ATOM   6155  O O   . ALA B 1 237 ? 87.328  132.718 97.271  1.00 108.63 ? 237 ALA B O   1 
ATOM   6156  C CB  . ALA B 1 237 ? 88.504  129.912 97.360  1.00 99.93  ? 237 ALA B CB  1 
ATOM   6157  N N   . SER B 1 238 ? 85.893  131.788 98.692  1.00 97.91  ? 238 SER B N   1 
ATOM   6158  C CA  . SER B 1 238 ? 85.656  133.039 99.401  1.00 94.82  ? 238 SER B CA  1 
ATOM   6159  C C   . SER B 1 238 ? 86.817  133.333 100.349 1.00 96.55  ? 238 SER B C   1 
ATOM   6160  O O   . SER B 1 238 ? 87.112  132.536 101.235 1.00 96.76  ? 238 SER B O   1 
ATOM   6161  C CB  . SER B 1 238 ? 84.326  132.969 100.142 1.00 95.03  ? 238 SER B CB  1 
ATOM   6162  O OG  . SER B 1 238 ? 84.081  134.192 100.797 1.00 99.13  ? 238 SER B OG  1 
ATOM   6163  N N   . LEU B 1 239 ? 87.452  134.498 100.215 1.00 93.87  ? 239 LEU B N   1 
ATOM   6164  C CA  . LEU B 1 239 ? 88.427  134.986 101.197 1.00 91.60  ? 239 LEU B CA  1 
ATOM   6165  C C   . LEU B 1 239 ? 87.791  135.255 102.563 1.00 90.88  ? 239 LEU B C   1 
ATOM   6166  O O   . LEU B 1 239 ? 88.506  135.339 103.549 1.00 90.25  ? 239 LEU B O   1 
ATOM   6167  C CB  . LEU B 1 239 ? 89.108  136.258 100.667 1.00 92.24  ? 239 LEU B CB  1 
ATOM   6168  C CG  . LEU B 1 239 ? 90.169  135.947 99.608  1.00 91.60  ? 239 LEU B CG  1 
ATOM   6169  C CD1 . LEU B 1 239 ? 90.453  137.162 98.744  1.00 94.30  ? 239 LEU B CD1 1 
ATOM   6170  C CD2 . LEU B 1 239 ? 91.483  135.519 100.251 1.00 87.45  ? 239 LEU B CD2 1 
ATOM   6171  N N   . GLU B 1 240 ? 86.467  135.372 102.649 1.00 99.05  ? 240 GLU B N   1 
ATOM   6172  C CA  . GLU B 1 240 ? 85.736  135.518 103.908 1.00 101.82 ? 240 GLU B CA  1 
ATOM   6173  C C   . GLU B 1 240 ? 85.467  134.181 104.622 1.00 104.53 ? 240 GLU B C   1 
ATOM   6174  O O   . GLU B 1 240 ? 84.948  134.186 105.737 1.00 105.99 ? 240 GLU B O   1 
ATOM   6175  C CB  . GLU B 1 240 ? 84.390  136.213 103.656 1.00 101.81 ? 240 GLU B CB  1 
ATOM   6176  C CG  . GLU B 1 240 ? 84.474  137.507 102.848 1.00 103.97 ? 240 GLU B CG  1 
ATOM   6177  C CD  . GLU B 1 240 ? 83.084  138.144 102.709 1.00 106.97 ? 240 GLU B CD  1 
ATOM   6178  O OE1 . GLU B 1 240 ? 82.437  138.426 103.741 1.00 103.77 ? 240 GLU B OE1 1 
ATOM   6179  O OE2 . GLU B 1 240 ? 82.624  138.347 101.565 1.00 105.08 ? 240 GLU B OE2 1 
ATOM   6180  N N   . ALA B 1 241 ? 85.747  133.031 104.000 1.00 92.00  ? 241 ALA B N   1 
ATOM   6181  C CA  . ALA B 1 241 ? 85.440  131.714 104.560 1.00 88.39  ? 241 ALA B CA  1 
ATOM   6182  C C   . ALA B 1 241 ? 86.309  131.370 105.776 1.00 88.54  ? 241 ALA B C   1 
ATOM   6183  O O   . ALA B 1 241 ? 87.492  131.704 105.829 1.00 91.13  ? 241 ALA B O   1 
ATOM   6184  C CB  . ALA B 1 241 ? 85.578  130.654 103.471 1.00 87.38  ? 241 ALA B CB  1 
ATOM   6185  N N   . THR B 1 242 ? 85.727  130.662 106.744 1.00 82.95  ? 242 THR B N   1 
ATOM   6186  C CA  . THR B 1 242 ? 86.335  130.389 108.052 1.00 85.09  ? 242 THR B CA  1 
ATOM   6187  C C   . THR B 1 242 ? 86.334  128.911 108.424 1.00 91.34  ? 242 THR B C   1 
ATOM   6188  O O   . THR B 1 242 ? 85.382  128.189 108.141 1.00 89.94  ? 242 THR B O   1 
ATOM   6189  C CB  . THR B 1 242 ? 85.617  131.163 109.162 1.00 85.26  ? 242 THR B CB  1 
ATOM   6190  O OG1 . THR B 1 242 ? 84.250  130.824 109.221 1.00 90.68  ? 242 THR B OG1 1 
ATOM   6191  C CG2 . THR B 1 242 ? 85.706  132.674 109.011 1.00 86.22  ? 242 THR B CG2 1 
ATOM   6192  N N   . ASP B 1 243 ? 87.372  128.467 109.128 1.00 81.71  ? 243 ASP B N   1 
ATOM   6193  C CA  . ASP B 1 243 ? 87.428  127.138 109.737 1.00 73.84  ? 243 ASP B CA  1 
ATOM   6194  C C   . ASP B 1 243 ? 86.569  126.998 111.022 1.00 79.08  ? 243 ASP B C   1 
ATOM   6195  O O   . ASP B 1 243 ? 85.827  127.909 111.391 1.00 80.19  ? 243 ASP B O   1 
ATOM   6196  C CB  . ASP B 1 243 ? 88.901  126.767 109.937 1.00 78.49  ? 243 ASP B CB  1 
ATOM   6197  C CG  . ASP B 1 243 ? 89.628  127.323 111.159 1.00 82.11  ? 243 ASP B CG  1 
ATOM   6198  O OD1 . ASP B 1 243 ? 88.996  128.024 111.971 1.00 88.38  ? 243 ASP B OD1 1 
ATOM   6199  O OD2 . ASP B 1 243 ? 90.835  127.028 111.293 1.00 88.00  ? 243 ASP B OD2 1 
ATOM   6200  N N   . SER B 1 244 ? 86.650  125.861 111.723 1.00 90.34  ? 244 SER B N   1 
ATOM   6201  C CA  . SER B 1 244 ? 85.911  125.602 112.973 1.00 90.42  ? 244 SER B CA  1 
ATOM   6202  C C   . SER B 1 244 ? 86.269  126.517 114.148 1.00 87.38  ? 244 SER B C   1 
ATOM   6203  O O   . SER B 1 244 ? 85.462  126.650 115.067 1.00 85.83  ? 244 SER B O   1 
ATOM   6204  C CB  . SER B 1 244 ? 86.128  124.157 113.433 1.00 88.89  ? 244 SER B CB  1 
ATOM   6205  O OG  . SER B 1 244 ? 87.443  123.938 113.889 1.00 90.21  ? 244 SER B OG  1 
ATOM   6206  N N   . LEU B 1 245 ? 87.438  127.159 114.145 1.00 79.85  ? 245 LEU B N   1 
ATOM   6207  C CA  . LEU B 1 245 ? 87.847  128.176 115.121 1.00 80.26  ? 245 LEU B CA  1 
ATOM   6208  C C   . LEU B 1 245 ? 87.437  129.589 114.682 1.00 83.37  ? 245 LEU B C   1 
ATOM   6209  O O   . LEU B 1 245 ? 87.715  130.562 115.380 1.00 85.23  ? 245 LEU B O   1 
ATOM   6210  C CB  . LEU B 1 245 ? 89.370  128.123 115.342 1.00 83.81  ? 245 LEU B CB  1 
ATOM   6211  C CG  . LEU B 1 245 ? 89.949  126.757 115.727 1.00 86.52  ? 245 LEU B CG  1 
ATOM   6212  C CD1 . LEU B 1 245 ? 91.460  126.886 115.903 1.00 82.97  ? 245 LEU B CD1 1 
ATOM   6213  C CD2 . LEU B 1 245 ? 89.349  126.232 117.029 1.00 84.76  ? 245 LEU B CD2 1 
ATOM   6214  N N   . GLY B 1 246 ? 86.819  129.728 113.510 1.00 81.20  ? 246 GLY B N   1 
ATOM   6215  C CA  . GLY B 1 246 ? 86.514  131.004 112.881 1.00 71.44  ? 246 GLY B CA  1 
ATOM   6216  C C   . GLY B 1 246 ? 87.707  131.631 112.159 1.00 73.50  ? 246 GLY B C   1 
ATOM   6217  O O   . GLY B 1 246 ? 87.603  132.762 111.701 1.00 83.55  ? 246 GLY B O   1 
ATOM   6218  N N   . ASN B 1 247 ? 88.846  130.946 112.046 1.00 71.61  ? 247 ASN B N   1 
ATOM   6219  C CA  . ASN B 1 247 ? 90.031  131.479 111.390 1.00 67.02  ? 247 ASN B CA  1 
ATOM   6220  C C   . ASN B 1 247 ? 89.815  131.573 109.876 1.00 73.09  ? 247 ASN B C   1 
ATOM   6221  O O   . ASN B 1 247 ? 89.478  130.594 109.219 1.00 74.88  ? 247 ASN B O   1 
ATOM   6222  C CB  . ASN B 1 247 ? 91.258  130.623 111.744 1.00 63.32  ? 247 ASN B CB  1 
ATOM   6223  C CG  . ASN B 1 247 ? 91.815  130.889 113.125 1.00 69.90  ? 247 ASN B CG  1 
ATOM   6224  O OD1 . ASN B 1 247 ? 91.456  131.826 113.806 1.00 78.84  ? 247 ASN B OD1 1 
ATOM   6225  N ND2 . ASN B 1 247 ? 92.749  130.102 113.579 1.00 75.50  ? 247 ASN B ND2 1 
ATOM   6226  N N   . THR B 1 248 ? 90.046  132.758 109.321 1.00 81.91  ? 248 THR B N   1 
ATOM   6227  C CA  . THR B 1 248 ? 90.177  133.022 107.881 1.00 78.55  ? 248 THR B CA  1 
ATOM   6228  C C   . THR B 1 248 ? 91.581  132.613 107.412 1.00 74.39  ? 248 THR B C   1 
ATOM   6229  O O   . THR B 1 248 ? 92.451  132.354 108.241 1.00 75.25  ? 248 THR B O   1 
ATOM   6230  C CB  . THR B 1 248 ? 89.885  134.519 107.642 1.00 80.79  ? 248 THR B CB  1 
ATOM   6231  O OG1 . THR B 1 248 ? 88.596  134.822 108.110 1.00 75.16  ? 248 THR B OG1 1 
ATOM   6232  C CG2 . THR B 1 248 ? 89.907  134.964 106.194 1.00 82.91  ? 248 THR B CG2 1 
ATOM   6233  N N   . VAL B 1 249 ? 91.878  132.581 106.114 1.00 62.90  ? 249 VAL B N   1 
ATOM   6234  C CA  . VAL B 1 249 ? 93.227  132.248 105.604 1.00 65.71  ? 249 VAL B CA  1 
ATOM   6235  C C   . VAL B 1 249 ? 94.344  133.129 106.187 1.00 72.87  ? 249 VAL B C   1 
ATOM   6236  O O   . VAL B 1 249 ? 95.462  132.663 106.370 1.00 81.07  ? 249 VAL B O   1 
ATOM   6237  C CB  . VAL B 1 249 ? 93.250  132.224 104.063 1.00 64.51  ? 249 VAL B CB  1 
ATOM   6238  C CG1 . VAL B 1 249 ? 92.906  133.555 103.404 1.00 71.51  ? 249 VAL B CG1 1 
ATOM   6239  C CG2 . VAL B 1 249 ? 94.613  131.787 103.538 1.00 67.79  ? 249 VAL B CG2 1 
ATOM   6240  N N   . LEU B 1 250 ? 94.040  134.374 106.566 1.00 71.29  ? 250 LEU B N   1 
ATOM   6241  C CA  . LEU B 1 250 ? 94.987  135.300 107.187 1.00 63.40  ? 250 LEU B CA  1 
ATOM   6242  C C   . LEU B 1 250 ? 95.267  134.959 108.659 1.00 66.69  ? 250 LEU B C   1 
ATOM   6243  O O   . LEU B 1 250 ? 96.404  135.076 109.099 1.00 70.71  ? 250 LEU B O   1 
ATOM   6244  C CB  . LEU B 1 250 ? 94.486  136.744 107.011 1.00 70.30  ? 250 LEU B CB  1 
ATOM   6245  C CG  . LEU B 1 250 ? 94.316  137.234 105.561 1.00 64.05  ? 250 LEU B CG  1 
ATOM   6246  C CD1 . LEU B 1 250 ? 93.878  138.690 105.568 1.00 68.54  ? 250 LEU B CD1 1 
ATOM   6247  C CD2 . LEU B 1 250 ? 95.600  137.136 104.746 1.00 65.55  ? 250 LEU B CD2 1 
ATOM   6248  N N   . HIS B 1 251 ? 94.280  134.459 109.394 1.00 65.41  ? 251 HIS B N   1 
ATOM   6249  C CA  . HIS B 1 251 ? 94.520  133.864 110.697 1.00 62.50  ? 251 HIS B CA  1 
ATOM   6250  C C   . HIS B 1 251 ? 95.301  132.558 110.578 1.00 71.34  ? 251 HIS B C   1 
ATOM   6251  O O   . HIS B 1 251 ? 96.182  132.305 111.388 1.00 80.41  ? 251 HIS B O   1 
ATOM   6252  C CB  . HIS B 1 251 ? 93.197  133.587 111.394 1.00 71.17  ? 251 HIS B CB  1 
ATOM   6253  C CG  . HIS B 1 251 ? 92.261  134.746 111.549 1.00 67.08  ? 251 HIS B CG  1 
ATOM   6254  N ND1 . HIS B 1 251 ? 91.314  135.139 110.611 1.00 61.43  ? 251 HIS B ND1 1 
ATOM   6255  C CD2 . HIS B 1 251 ? 92.090  135.475 112.679 1.00 63.84  ? 251 HIS B CD2 1 
ATOM   6256  C CE1 . HIS B 1 251 ? 90.591  136.099 111.191 1.00 63.24  ? 251 HIS B CE1 1 
ATOM   6257  N NE2 . HIS B 1 251 ? 91.034  136.311 112.433 1.00 68.48  ? 251 HIS B NE2 1 
ATOM   6258  N N   . ALA B 1 252 ? 95.019  131.738 109.565 1.00 63.39  ? 252 ALA B N   1 
ATOM   6259  C CA  . ALA B 1 252 ? 95.751  130.501 109.321 1.00 56.92  ? 252 ALA B CA  1 
ATOM   6260  C C   . ALA B 1 252 ? 97.232  130.764 109.037 1.00 61.20  ? 252 ALA B C   1 
ATOM   6261  O O   . ALA B 1 252 ? 98.084  130.169 109.686 1.00 74.16  ? 252 ALA B O   1 
ATOM   6262  C CB  . ALA B 1 252 ? 95.075  129.720 108.196 1.00 57.80  ? 252 ALA B CB  1 
ATOM   6263  N N   . LEU B 1 253 ? 97.569  131.718 108.171 1.00 66.34  ? 253 LEU B N   1 
ATOM   6264  C CA  . LEU B 1 253 ? 98.954  132.133 107.929 1.00 59.45  ? 253 LEU B CA  1 
ATOM   6265  C C   . LEU B 1 253 ? 99.644  132.693 109.175 1.00 54.46  ? 253 LEU B C   1 
ATOM   6266  O O   . LEU B 1 253 ? 100.806 132.394 109.413 1.00 63.43  ? 253 LEU B O   1 
ATOM   6267  C CB  . LEU B 1 253 ? 98.978  133.169 106.804 1.00 60.41  ? 253 LEU B CB  1 
ATOM   6268  C CG  . LEU B 1 253 ? 98.812  132.551 105.416 1.00 60.40  ? 253 LEU B CG  1 
ATOM   6269  C CD1 . LEU B 1 253 ? 98.603  133.667 104.413 1.00 65.56  ? 253 LEU B CD1 1 
ATOM   6270  C CD2 . LEU B 1 253 ? 100.050 131.778 104.970 1.00 63.82  ? 253 LEU B CD2 1 
ATOM   6271  N N   . VAL B 1 254 ? 98.943  133.439 110.027 1.00 63.22  ? 254 VAL B N   1 
ATOM   6272  C CA  . VAL B 1 254 ? 99.489  133.882 111.320 1.00 62.49  ? 254 VAL B CA  1 
ATOM   6273  C C   . VAL B 1 254 ? 99.727  132.704 112.267 1.00 63.46  ? 254 VAL B C   1 
ATOM   6274  O O   . VAL B 1 254 ? 100.752 132.656 112.945 1.00 73.90  ? 254 VAL B O   1 
ATOM   6275  C CB  . VAL B 1 254 ? 98.571  134.946 111.933 1.00 67.15  ? 254 VAL B CB  1 
ATOM   6276  C CG1 . VAL B 1 254 ? 98.910  135.234 113.387 1.00 73.00  ? 254 VAL B CG1 1 
ATOM   6277  C CG2 . VAL B 1 254 ? 98.701  136.263 111.168 1.00 64.15  ? 254 VAL B CG2 1 
ATOM   6278  N N   . MET B 1 255 ? 98.847  131.704 112.301 1.00 67.69  ? 255 MET B N   1 
ATOM   6279  C CA  . MET B 1 255 ? 99.043  130.495 113.112 1.00 65.98  ? 255 MET B CA  1 
ATOM   6280  C C   . MET B 1 255 ? 100.276 129.693 112.684 1.00 69.56  ? 255 MET B C   1 
ATOM   6281  O O   . MET B 1 255 ? 100.957 129.117 113.526 1.00 73.49  ? 255 MET B O   1 
ATOM   6282  C CB  . MET B 1 255 ? 97.804  129.598 113.037 1.00 65.07  ? 255 MET B CB  1 
ATOM   6283  C CG  . MET B 1 255 ? 96.662  130.102 113.906 1.00 61.67  ? 255 MET B CG  1 
ATOM   6284  S SD  . MET B 1 255 ? 97.013  129.982 115.677 1.00 79.34  ? 255 MET B SD  1 
ATOM   6285  C CE  . MET B 1 255 ? 95.321  129.904 116.308 1.00 69.47  ? 255 MET B CE  1 
ATOM   6286  N N   . ILE B 1 256 ? 100.595 129.705 111.395 1.00 77.73  ? 256 ILE B N   1 
ATOM   6287  C CA  . ILE B 1 256 ? 101.644 128.901 110.747 1.00 72.38  ? 256 ILE B CA  1 
ATOM   6288  C C   . ILE B 1 256 ? 102.986 129.623 110.614 1.00 75.84  ? 256 ILE B C   1 
ATOM   6289  O O   . ILE B 1 256 ? 104.009 128.985 110.371 1.00 80.29  ? 256 ILE B O   1 
ATOM   6290  C CB  . ILE B 1 256 ? 101.041 128.415 109.421 1.00 72.64  ? 256 ILE B CB  1 
ATOM   6291  C CG1 . ILE B 1 256 ? 100.102 127.265 109.825 1.00 75.38  ? 256 ILE B CG1 1 
ATOM   6292  C CG2 . ILE B 1 256 ? 102.019 127.986 108.333 1.00 69.78  ? 256 ILE B CG2 1 
ATOM   6293  C CD1 . ILE B 1 256 ? 98.961  127.063 108.859 1.00 75.53  ? 256 ILE B CD1 1 
ATOM   6294  N N   . ALA B 1 257 ? 103.021 130.932 110.848 1.00 77.53  ? 257 ALA B N   1 
ATOM   6295  C CA  . ALA B 1 257 ? 104.263 131.679 110.935 1.00 74.31  ? 257 ALA B CA  1 
ATOM   6296  C C   . ALA B 1 257 ? 105.167 131.134 112.051 1.00 78.91  ? 257 ALA B C   1 
ATOM   6297  O O   . ALA B 1 257 ? 104.732 130.986 113.189 1.00 82.87  ? 257 ALA B O   1 
ATOM   6298  C CB  . ALA B 1 257 ? 103.936 133.153 111.156 1.00 75.42  ? 257 ALA B CB  1 
ATOM   6299  N N   . ASP B 1 258 ? 106.439 130.922 111.750 1.00 97.99  ? 258 ASP B N   1 
ATOM   6300  C CA  . ASP B 1 258 ? 107.530 130.714 112.699 1.00 99.80  ? 258 ASP B CA  1 
ATOM   6301  C C   . ASP B 1 258 ? 108.511 131.877 112.542 1.00 105.01 ? 258 ASP B C   1 
ATOM   6302  O O   . ASP B 1 258 ? 108.654 132.448 111.461 1.00 105.93 ? 258 ASP B O   1 
ATOM   6303  C CB  . ASP B 1 258 ? 108.252 129.379 112.458 1.00 101.45 ? 258 ASP B CB  1 
ATOM   6304  C CG  . ASP B 1 258 ? 107.492 128.143 112.951 1.00 107.18 ? 258 ASP B CG  1 
ATOM   6305  O OD1 . ASP B 1 258 ? 106.637 128.265 113.851 1.00 108.56 ? 258 ASP B OD1 1 
ATOM   6306  O OD2 . ASP B 1 258 ? 107.823 127.028 112.496 1.00 104.13 ? 258 ASP B OD2 1 
ATOM   6307  N N   . ASN B 1 259 ? 109.190 132.260 113.614 1.00 101.43 ? 259 ASN B N   1 
ATOM   6308  C CA  . ASN B 1 259 ? 110.000 133.478 113.627 1.00 103.46 ? 259 ASN B CA  1 
ATOM   6309  C C   . ASN B 1 259 ? 111.371 133.322 112.929 1.00 104.57 ? 259 ASN B C   1 
ATOM   6310  O O   . ASN B 1 259 ? 112.245 134.173 113.075 1.00 104.00 ? 259 ASN B O   1 
ATOM   6311  C CB  . ASN B 1 259 ? 110.076 134.001 115.069 1.00 101.81 ? 259 ASN B CB  1 
ATOM   6312  C CG  . ASN B 1 259 ? 108.698 134.176 115.683 1.00 98.20  ? 259 ASN B CG  1 
ATOM   6313  O OD1 . ASN B 1 259 ? 107.875 134.943 115.214 1.00 94.50  ? 259 ASN B OD1 1 
ATOM   6314  N ND2 . ASN B 1 259 ? 108.389 133.448 116.731 1.00 99.37  ? 259 ASN B ND2 1 
ATOM   6315  N N   . SER B 1 260 ? 111.585 132.240 112.173 1.00 106.87 ? 260 SER B N   1 
ATOM   6316  C CA  . SER B 1 260 ? 112.774 132.030 111.344 1.00 106.29 ? 260 SER B CA  1 
ATOM   6317  C C   . SER B 1 260 ? 112.707 132.869 110.060 1.00 105.46 ? 260 SER B C   1 
ATOM   6318  O O   . SER B 1 260 ? 111.616 133.166 109.569 1.00 106.21 ? 260 SER B O   1 
ATOM   6319  C CB  . SER B 1 260 ? 112.929 130.539 111.026 1.00 106.59 ? 260 SER B CB  1 
ATOM   6320  O OG  . SER B 1 260 ? 111.847 130.067 110.250 1.00 105.89 ? 260 SER B OG  1 
ATOM   6321  N N   . PRO B 1 261 ? 113.845 133.272 109.468 1.00 109.40 ? 261 PRO B N   1 
ATOM   6322  C CA  . PRO B 1 261 ? 113.841 134.181 108.321 1.00 111.20 ? 261 PRO B CA  1 
ATOM   6323  C C   . PRO B 1 261 ? 113.270 133.542 107.049 1.00 108.89 ? 261 PRO B C   1 
ATOM   6324  O O   . PRO B 1 261 ? 112.682 134.237 106.229 1.00 102.36 ? 261 PRO B O   1 
ATOM   6325  C CB  . PRO B 1 261 ? 115.297 134.613 108.145 1.00 109.67 ? 261 PRO B CB  1 
ATOM   6326  C CG  . PRO B 1 261 ? 116.099 133.473 108.764 1.00 106.65 ? 261 PRO B CG  1 
ATOM   6327  C CD  . PRO B 1 261 ? 115.203 133.006 109.905 1.00 107.01 ? 261 PRO B CD  1 
ATOM   6328  N N   . GLU B 1 262 ? 113.397 132.226 106.886 1.00 106.55 ? 262 GLU B N   1 
ATOM   6329  C CA  . GLU B 1 262 ? 112.889 131.502 105.714 1.00 108.72 ? 262 GLU B CA  1 
ATOM   6330  C C   . GLU B 1 262 ? 111.367 131.328 105.748 1.00 111.14 ? 262 GLU B C   1 
ATOM   6331  O O   . GLU B 1 262 ? 110.695 131.606 104.756 1.00 110.11 ? 262 GLU B O   1 
ATOM   6332  C CB  . GLU B 1 262 ? 113.584 130.135 105.603 1.00 104.30 ? 262 GLU B CB  1 
ATOM   6333  N N   . ASN B 1 263 ? 110.795 130.919 106.882 1.00 98.28  ? 263 ASN B N   1 
ATOM   6334  C CA  . ASN B 1 263 ? 109.343 130.815 107.032 1.00 94.80  ? 263 ASN B CA  1 
ATOM   6335  C C   . ASN B 1 263 ? 108.700 132.202 106.984 1.00 100.69 ? 263 ASN B C   1 
ATOM   6336  O O   . ASN B 1 263 ? 107.838 132.452 106.145 1.00 101.17 ? 263 ASN B O   1 
ATOM   6337  C CB  . ASN B 1 263 ? 109.017 130.061 108.330 1.00 97.16  ? 263 ASN B CB  1 
ATOM   6338  C CG  . ASN B 1 263 ? 107.532 130.018 108.641 1.00 97.70  ? 263 ASN B CG  1 
ATOM   6339  O OD1 . ASN B 1 263 ? 106.929 131.025 108.956 1.00 100.84 ? 263 ASN B OD1 1 
ATOM   6340  N ND2 . ASN B 1 263 ? 106.899 128.880 108.604 1.00 95.96  ? 263 ASN B ND2 1 
ATOM   6341  N N   . SER B 1 264 ? 109.133 133.124 107.848 1.00 97.85  ? 264 SER B N   1 
ATOM   6342  C CA  . SER B 1 264 ? 108.459 134.414 107.997 1.00 90.45  ? 264 SER B CA  1 
ATOM   6343  C C   . SER B 1 264 ? 108.475 135.236 106.716 1.00 90.04  ? 264 SER B C   1 
ATOM   6344  O O   . SER B 1 264 ? 107.429 135.760 106.351 1.00 95.19  ? 264 SER B O   1 
ATOM   6345  C CB  . SER B 1 264 ? 109.039 135.217 109.156 1.00 92.08  ? 264 SER B CB  1 
ATOM   6346  O OG  . SER B 1 264 ? 110.412 135.467 108.971 1.00 96.92  ? 264 SER B OG  1 
ATOM   6347  N N   . ALA B 1 265 ? 109.577 135.298 105.964 1.00 96.79  ? 265 ALA B N   1 
ATOM   6348  C CA  . ALA B 1 265 ? 109.608 136.028 104.696 1.00 96.00  ? 265 ALA B CA  1 
ATOM   6349  C C   . ALA B 1 265 ? 108.611 135.470 103.675 1.00 95.18  ? 265 ALA B C   1 
ATOM   6350  O O   . ALA B 1 265 ? 107.932 136.234 102.994 1.00 91.71  ? 265 ALA B O   1 
ATOM   6351  C CB  . ALA B 1 265 ? 111.027 135.998 104.139 1.00 95.92  ? 265 ALA B CB  1 
ATOM   6352  N N   . LEU B 1 266 ? 108.463 134.147 103.587 1.00 94.03  ? 266 LEU B N   1 
ATOM   6353  C CA  . LEU B 1 266 ? 107.527 133.514 102.660 1.00 95.89  ? 266 LEU B CA  1 
ATOM   6354  C C   . LEU B 1 266 ? 106.066 133.611 103.125 1.00 94.82  ? 266 LEU B C   1 
ATOM   6355  O O   . LEU B 1 266 ? 105.186 133.812 102.300 1.00 92.68  ? 266 LEU B O   1 
ATOM   6356  C CB  . LEU B 1 266 ? 107.958 132.062 102.418 1.00 95.50  ? 266 LEU B CB  1 
ATOM   6357  C CG  . LEU B 1 266 ? 109.312 131.909 101.698 1.00 99.04  ? 266 LEU B CG  1 
ATOM   6358  C CD1 . LEU B 1 266 ? 109.688 130.434 101.616 1.00 95.37  ? 266 LEU B CD1 1 
ATOM   6359  C CD2 . LEU B 1 266 ? 109.277 132.455 100.273 1.00 95.33  ? 266 LEU B CD2 1 
ATOM   6360  N N   . VAL B 1 267 ? 105.792 133.552 104.433 1.00 88.41  ? 267 VAL B N   1 
ATOM   6361  C CA  . VAL B 1 267 ? 104.455 133.832 104.994 1.00 86.31  ? 267 VAL B CA  1 
ATOM   6362  C C   . VAL B 1 267 ? 104.053 135.287 104.770 1.00 83.60  ? 267 VAL B C   1 
ATOM   6363  O O   . VAL B 1 267 ? 102.911 135.542 104.419 1.00 85.44  ? 267 VAL B O   1 
ATOM   6364  C CB  . VAL B 1 267 ? 104.381 133.470 106.485 1.00 79.39  ? 267 VAL B CB  1 
ATOM   6365  C CG1 . VAL B 1 267 ? 103.092 133.955 107.148 1.00 81.05  ? 267 VAL B CG1 1 
ATOM   6366  C CG2 . VAL B 1 267 ? 104.425 131.952 106.652 1.00 84.91  ? 267 VAL B CG2 1 
ATOM   6367  N N   . ILE B 1 268 ? 104.973 136.238 104.912 1.00 78.98  ? 268 ILE B N   1 
ATOM   6368  C CA  . ILE B 1 268 ? 104.743 137.659 104.641 1.00 73.75  ? 268 ILE B CA  1 
ATOM   6369  C C   . ILE B 1 268 ? 104.362 137.892 103.174 1.00 81.37  ? 268 ILE B C   1 
ATOM   6370  O O   . ILE B 1 268 ? 103.404 138.603 102.897 1.00 84.20  ? 268 ILE B O   1 
ATOM   6371  C CB  . ILE B 1 268 ? 105.990 138.452 105.080 1.00 79.17  ? 268 ILE B CB  1 
ATOM   6372  C CG1 . ILE B 1 268 ? 105.948 138.630 106.611 1.00 74.90  ? 268 ILE B CG1 1 
ATOM   6373  C CG2 . ILE B 1 268 ? 106.119 139.801 104.369 1.00 81.25  ? 268 ILE B CG2 1 
ATOM   6374  C CD1 . ILE B 1 268 ? 107.285 139.062 107.215 1.00 76.43  ? 268 ILE B CD1 1 
ATOM   6375  N N   . HIS B 1 269 ? 105.040 137.246 102.223 1.00 94.96  ? 269 HIS B N   1 
ATOM   6376  C CA  . HIS B 1 269 ? 104.655 137.322 100.812 1.00 92.26  ? 269 HIS B CA  1 
ATOM   6377  C C   . HIS B 1 269 ? 103.290 136.688 100.544 1.00 89.43  ? 269 HIS B C   1 
ATOM   6378  O O   . HIS B 1 269 ? 102.467 137.275 99.849  1.00 89.89  ? 269 HIS B O   1 
ATOM   6379  C CB  . HIS B 1 269 ? 105.727 136.680 99.926  1.00 88.74  ? 269 HIS B CB  1 
ATOM   6380  C CG  . HIS B 1 269 ? 106.938 137.555 99.754  1.00 95.88  ? 269 HIS B CG  1 
ATOM   6381  N ND1 . HIS B 1 269 ? 107.932 137.773 100.676 1.00 98.33  ? 269 HIS B ND1 1 
ATOM   6382  C CD2 . HIS B 1 269 ? 107.182 138.397 98.710  1.00 96.27  ? 269 HIS B CD2 1 
ATOM   6383  C CE1 . HIS B 1 269 ? 108.765 138.708 100.196 1.00 97.81  ? 269 HIS B CE1 1 
ATOM   6384  N NE2 . HIS B 1 269 ? 108.345 139.122 98.992  1.00 97.81  ? 269 HIS B NE2 1 
ATOM   6385  N N   . MET B 1 270 ? 103.026 135.510 101.109 1.00 85.31  ? 270 MET B N   1 
ATOM   6386  C CA  . MET B 1 270 ? 101.743 134.826 100.963 1.00 82.46  ? 270 MET B CA  1 
ATOM   6387  C C   . MET B 1 270 ? 100.585 135.636 101.552 1.00 82.81  ? 270 MET B C   1 
ATOM   6388  O O   . MET B 1 270 ? 99.538  135.764 100.926 1.00 82.60  ? 270 MET B O   1 
ATOM   6389  C CB  . MET B 1 270 ? 101.858 133.439 101.595 1.00 79.32  ? 270 MET B CB  1 
ATOM   6390  C CG  . MET B 1 270 ? 100.719 132.512 101.188 1.00 83.59  ? 270 MET B CG  1 
ATOM   6391  S SD  . MET B 1 270 ? 100.803 131.909 99.484  1.00 81.19  ? 270 MET B SD  1 
ATOM   6392  C CE  . MET B 1 270 ? 99.321  132.697 98.841  1.00 88.79  ? 270 MET B CE  1 
ATOM   6393  N N   . TYR B 1 271 ? 100.787 136.253 102.714 1.00 81.71  ? 271 TYR B N   1 
ATOM   6394  C CA  . TYR B 1 271 ? 99.821  137.129 103.368 1.00 77.50  ? 271 TYR B CA  1 
ATOM   6395  C C   . TYR B 1 271 ? 99.529  138.381 102.531 1.00 78.91  ? 271 TYR B C   1 
ATOM   6396  O O   . TYR B 1 271 ? 98.374  138.681 102.251 1.00 78.22  ? 271 TYR B O   1 
ATOM   6397  C CB  . TYR B 1 271 ? 100.379 137.484 104.752 1.00 79.14  ? 271 TYR B CB  1 
ATOM   6398  C CG  . TYR B 1 271 ? 99.418  138.201 105.669 1.00 75.78  ? 271 TYR B CG  1 
ATOM   6399  C CD1 . TYR B 1 271 ? 99.087  139.547 105.440 1.00 72.86  ? 271 TYR B CD1 1 
ATOM   6400  C CD2 . TYR B 1 271 ? 98.858  137.518 106.764 1.00 75.64  ? 271 TYR B CD2 1 
ATOM   6401  C CE1 . TYR B 1 271 ? 98.165  140.195 106.273 1.00 75.68  ? 271 TYR B CE1 1 
ATOM   6402  C CE2 . TYR B 1 271 ? 97.957  138.175 107.616 1.00 76.79  ? 271 TYR B CE2 1 
ATOM   6403  C CZ  . TYR B 1 271 ? 97.602  139.512 107.364 1.00 80.94  ? 271 TYR B CZ  1 
ATOM   6404  O OH  . TYR B 1 271 ? 96.731  140.145 108.182 1.00 79.16  ? 271 TYR B OH  1 
ATOM   6405  N N   . ASP B 1 272 ? 100.563 139.096 102.084 1.00 83.27  ? 272 ASP B N   1 
ATOM   6406  C CA  . ASP B 1 272 ? 100.415 140.302 101.270 1.00 80.53  ? 272 ASP B CA  1 
ATOM   6407  C C   . ASP B 1 272 ? 99.699  140.044 99.950  1.00 88.88  ? 272 ASP B C   1 
ATOM   6408  O O   . ASP B 1 272 ? 98.793  140.795 99.603  1.00 91.18  ? 272 ASP B O   1 
ATOM   6409  C CB  . ASP B 1 272 ? 101.781 140.919 100.962 1.00 86.28  ? 272 ASP B CB  1 
ATOM   6410  C CG  . ASP B 1 272 ? 102.386 141.706 102.119 1.00 93.60  ? 272 ASP B CG  1 
ATOM   6411  O OD1 . ASP B 1 272 ? 101.695 141.941 103.132 1.00 94.12  ? 272 ASP B OD1 1 
ATOM   6412  O OD2 . ASP B 1 272 ? 103.537 142.170 101.969 1.00 93.96  ? 272 ASP B OD2 1 
ATOM   6413  N N   . GLY B 1 273 ? 100.054 138.998 99.202  1.00 86.29  ? 273 GLY B N   1 
ATOM   6414  C CA  . GLY B 1 273 ? 99.367  138.724 97.941  1.00 77.94  ? 273 GLY B CA  1 
ATOM   6415  C C   . GLY B 1 273 ? 97.905  138.319 98.128  1.00 81.71  ? 273 GLY B C   1 
ATOM   6416  O O   . GLY B 1 273 ? 97.071  138.704 97.317  1.00 82.01  ? 273 GLY B O   1 
ATOM   6417  N N   . LEU B 1 274 ? 97.545  137.610 99.200  1.00 85.75  ? 274 LEU B N   1 
ATOM   6418  C CA  . LEU B 1 274 ? 96.143  137.330 99.520  1.00 84.59  ? 274 LEU B CA  1 
ATOM   6419  C C   . LEU B 1 274 ? 95.380  138.589 99.918  1.00 85.15  ? 274 LEU B C   1 
ATOM   6420  O O   . LEU B 1 274 ? 94.273  138.808 99.441  1.00 87.11  ? 274 LEU B O   1 
ATOM   6421  C CB  . LEU B 1 274 ? 96.061  136.325 100.672 1.00 84.30  ? 274 LEU B CB  1 
ATOM   6422  C CG  . LEU B 1 274 ? 96.417  134.890 100.287 1.00 79.88  ? 274 LEU B CG  1 
ATOM   6423  C CD1 . LEU B 1 274 ? 96.503  134.085 101.567 1.00 84.99  ? 274 LEU B CD1 1 
ATOM   6424  C CD2 . LEU B 1 274 ? 95.357  134.249 99.402  1.00 78.03  ? 274 LEU B CD2 1 
ATOM   6425  N N   . LEU B 1 275 ? 95.998  139.485 100.681 1.00 85.61  ? 275 LEU B N   1 
ATOM   6426  C CA  . LEU B 1 275 ? 95.421  140.779 101.026 1.00 83.56  ? 275 LEU B CA  1 
ATOM   6427  C C   . LEU B 1 275 ? 95.237  141.689 99.797  1.00 77.98  ? 275 LEU B C   1 
ATOM   6428  O O   . LEU B 1 275 ? 94.164  142.251 99.604  1.00 78.79  ? 275 LEU B O   1 
ATOM   6429  C CB  . LEU B 1 275 ? 96.328  141.408 102.088 1.00 80.71  ? 275 LEU B CB  1 
ATOM   6430  C CG  . LEU B 1 275 ? 95.748  142.668 102.717 1.00 78.82  ? 275 LEU B CG  1 
ATOM   6431  C CD1 . LEU B 1 275 ? 94.574  142.360 103.628 1.00 77.62  ? 275 LEU B CD1 1 
ATOM   6432  C CD2 . LEU B 1 275 ? 96.835  143.335 103.523 1.00 80.66  ? 275 LEU B CD2 1 
ATOM   6433  N N   . GLN B 1 276 ? 96.240  141.778 98.922  1.00 86.32  ? 276 GLN B N   1 
ATOM   6434  C CA  . GLN B 1 276 ? 96.140  142.463 97.632  1.00 85.04  ? 276 GLN B CA  1 
ATOM   6435  C C   . GLN B 1 276 ? 95.089  141.827 96.714  1.00 93.02  ? 276 GLN B C   1 
ATOM   6436  O O   . GLN B 1 276 ? 94.373  142.546 96.023  1.00 95.58  ? 276 GLN B O   1 
ATOM   6437  C CB  . GLN B 1 276 ? 97.505  142.472 96.933  1.00 86.48  ? 276 GLN B CB  1 
ATOM   6438  C CG  . GLN B 1 276 ? 98.546  143.366 97.621  1.00 92.30  ? 276 GLN B CG  1 
ATOM   6439  C CD  . GLN B 1 276 ? 99.962  143.138 97.086  1.00 92.88  ? 276 GLN B CD  1 
ATOM   6440  O OE1 . GLN B 1 276 ? 100.202 142.441 96.111  1.00 92.50  ? 276 GLN B OE1 1 
ATOM   6441  N NE2 . GLN B 1 276 ? 100.964 143.725 97.698  1.00 89.68  ? 276 GLN B NE2 1 
ATOM   6442  N N   . MET B 1 277 ? 94.922  140.499 96.714  1.00 101.83 ? 277 MET B N   1 
ATOM   6443  C CA  . MET B 1 277 ? 93.835  139.843 95.969  1.00 97.73  ? 277 MET B CA  1 
ATOM   6444  C C   . MET B 1 277 ? 92.458  140.097 96.588  1.00 99.00  ? 277 MET B C   1 
ATOM   6445  O O   . MET B 1 277 ? 91.494  140.298 95.857  1.00 97.69  ? 277 MET B O   1 
ATOM   6446  C CB  . MET B 1 277 ? 94.094  138.339 95.826  1.00 98.08  ? 277 MET B CB  1 
ATOM   6447  C CG  . MET B 1 277 ? 95.098  138.081 94.704  1.00 100.62 ? 277 MET B CG  1 
ATOM   6448  S SD  . MET B 1 277 ? 95.318  136.349 94.231  1.00 103.42 ? 277 MET B SD  1 
ATOM   6449  C CE  . MET B 1 277 ? 96.503  135.840 95.495  1.00 99.26  ? 277 MET B CE  1 
ATOM   6450  N N   . GLY B 1 278 ? 92.344  140.202 97.909  1.00 101.70 ? 278 GLY B N   1 
ATOM   6451  C CA  . GLY B 1 278 ? 91.124  140.658 98.571  1.00 104.06 ? 278 GLY B CA  1 
ATOM   6452  C C   . GLY B 1 278 ? 90.644  142.029 98.090  1.00 100.65 ? 278 GLY B C   1 
ATOM   6453  O O   . GLY B 1 278 ? 89.445  142.227 97.935  1.00 98.30  ? 278 GLY B O   1 
ATOM   6454  N N   . ALA B 1 279 ? 91.547  142.951 97.747  1.00 101.03 ? 279 ALA B N   1 
ATOM   6455  C CA  . ALA B 1 279 ? 91.182  144.245 97.175  1.00 100.76 ? 279 ALA B CA  1 
ATOM   6456  C C   . ALA B 1 279 ? 90.616  144.153 95.744  1.00 104.13 ? 279 ALA B C   1 
ATOM   6457  O O   . ALA B 1 279 ? 89.903  145.064 95.325  1.00 103.28 ? 279 ALA B O   1 
ATOM   6458  C CB  . ALA B 1 279 ? 92.388  145.183 97.247  1.00 99.05  ? 279 ALA B CB  1 
ATOM   6459  N N   . ARG B 1 280 ? 90.884  143.069 94.993  1.00 108.06 ? 280 ARG B N   1 
ATOM   6460  C CA  . ARG B 1 280 ? 90.227  142.784 93.701  1.00 105.91 ? 280 ARG B CA  1 
ATOM   6461  C C   . ARG B 1 280 ? 88.911  142.025 93.865  1.00 104.67 ? 280 ARG B C   1 
ATOM   6462  O O   . ARG B 1 280 ? 87.899  142.395 93.278  1.00 99.73  ? 280 ARG B O   1 
ATOM   6463  C CB  . ARG B 1 280 ? 91.137  141.967 92.769  1.00 104.87 ? 280 ARG B CB  1 
ATOM   6464  C CG  . ARG B 1 280 ? 92.529  142.558 92.536  1.00 102.45 ? 280 ARG B CG  1 
ATOM   6465  C CD  . ARG B 1 280 ? 93.158  142.008 91.249  1.00 103.35 ? 280 ARG B CD  1 
ATOM   6466  N NE  . ARG B 1 280 ? 93.206  140.531 91.192  1.00 107.39 ? 280 ARG B NE  1 
ATOM   6467  C CZ  . ARG B 1 280 ? 94.255  139.756 91.360  1.00 110.61 ? 280 ARG B CZ  1 
ATOM   6468  N NH1 . ARG B 1 280 ? 94.179  138.473 91.163  1.00 107.61 ? 280 ARG B NH1 1 
ATOM   6469  N NH2 . ARG B 1 280 ? 95.406  140.231 91.735  1.00 106.77 ? 280 ARG B NH2 1 
ATOM   6470  N N   . LEU B 1 281 ? 88.947  140.937 94.631  1.00 109.29 ? 281 LEU B N   1 
ATOM   6471  C CA  . LEU B 1 281 ? 87.898  139.915 94.708  1.00 108.79 ? 281 LEU B CA  1 
ATOM   6472  C C   . LEU B 1 281 ? 86.799  140.240 95.728  1.00 107.71 ? 281 LEU B C   1 
ATOM   6473  O O   . LEU B 1 281 ? 85.649  139.853 95.539  1.00 105.76 ? 281 LEU B O   1 
ATOM   6474  C CB  . LEU B 1 281 ? 88.567  138.575 95.062  1.00 108.14 ? 281 LEU B CB  1 
ATOM   6475  C CG  . LEU B 1 281 ? 89.631  138.100 94.061  1.00 106.33 ? 281 LEU B CG  1 
ATOM   6476  C CD1 . LEU B 1 281 ? 90.369  136.908 94.642  1.00 111.03 ? 281 LEU B CD1 1 
ATOM   6477  C CD2 . LEU B 1 281 ? 89.028  137.699 92.722  1.00 100.50 ? 281 LEU B CD2 1 
ATOM   6478  N N   . CYS B 1 282 ? 87.146  140.967 96.792  1.00 109.82 ? 282 CYS B N   1 
ATOM   6479  C CA  . CYS B 1 282 ? 86.276  141.330 97.909  1.00 109.67 ? 282 CYS B CA  1 
ATOM   6480  C C   . CYS B 1 282 ? 86.418  142.835 98.239  1.00 112.90 ? 282 CYS B C   1 
ATOM   6481  O O   . CYS B 1 282 ? 86.731  143.181 99.379  1.00 115.41 ? 282 CYS B O   1 
ATOM   6482  C CB  . CYS B 1 282 ? 86.636  140.454 99.125  1.00 110.02 ? 282 CYS B CB  1 
ATOM   6483  S SG  . CYS B 1 282 ? 86.542  138.684 98.772  1.00 117.30 ? 282 CYS B SG  1 
ATOM   6484  N N   . PRO B 1 283 ? 86.242  143.762 97.277  1.00 109.16 ? 283 PRO B N   1 
ATOM   6485  C CA  . PRO B 1 283 ? 86.765  145.126 97.386  1.00 108.02 ? 283 PRO B CA  1 
ATOM   6486  C C   . PRO B 1 283 ? 86.151  145.939 98.536  1.00 107.83 ? 283 PRO B C   1 
ATOM   6487  O O   . PRO B 1 283 ? 86.808  146.819 99.091  1.00 104.75 ? 283 PRO B O   1 
ATOM   6488  C CB  . PRO B 1 283 ? 86.481  145.769 96.025  1.00 107.57 ? 283 PRO B CB  1 
ATOM   6489  C CG  . PRO B 1 283 ? 85.304  144.969 95.469  1.00 107.46 ? 283 PRO B CG  1 
ATOM   6490  C CD  . PRO B 1 283 ? 85.567  143.566 96.003  1.00 107.52 ? 283 PRO B CD  1 
ATOM   6491  N N   . THR B 1 284 ? 84.907  145.646 98.910  1.00 110.82 ? 284 THR B N   1 
ATOM   6492  C CA  . THR B 1 284 ? 84.197  146.276 100.037 1.00 112.18 ? 284 THR B CA  1 
ATOM   6493  C C   . THR B 1 284 ? 84.507  145.649 101.403 1.00 108.37 ? 284 THR B C   1 
ATOM   6494  O O   . THR B 1 284 ? 84.041  146.160 102.423 1.00 104.00 ? 284 THR B O   1 
ATOM   6495  C CB  . THR B 1 284 ? 82.684  146.233 99.795  1.00 111.89 ? 284 THR B CB  1 
ATOM   6496  O OG1 . THR B 1 284 ? 82.256  144.904 99.599  1.00 111.16 ? 284 THR B OG1 1 
ATOM   6497  C CG2 . THR B 1 284 ? 82.270  147.034 98.565  1.00 106.16 ? 284 THR B CG2 1 
ATOM   6498  N N   . VAL B 1 285 ? 85.271  144.555 101.470 1.00 104.31 ? 285 VAL B N   1 
ATOM   6499  C CA  . VAL B 1 285 ? 85.469  143.767 102.695 1.00 103.96 ? 285 VAL B CA  1 
ATOM   6500  C C   . VAL B 1 285 ? 86.840  144.037 103.308 1.00 102.74 ? 285 VAL B C   1 
ATOM   6501  O O   . VAL B 1 285 ? 87.879  143.890 102.666 1.00 101.06 ? 285 VAL B O   1 
ATOM   6502  C CB  . VAL B 1 285 ? 85.288  142.257 102.449 1.00 103.27 ? 285 VAL B CB  1 
ATOM   6503  C CG1 . VAL B 1 285 ? 85.312  141.489 103.774 1.00 102.64 ? 285 VAL B CG1 1 
ATOM   6504  C CG2 . VAL B 1 285 ? 83.965  141.943 101.747 1.00 101.78 ? 285 VAL B CG2 1 
ATOM   6505  N N   . GLN B 1 286 ? 86.848  144.394 104.589 1.00 101.29 ? 286 GLN B N   1 
ATOM   6506  C CA  . GLN B 1 286 ? 88.056  144.577 105.389 1.00 98.47  ? 286 GLN B CA  1 
ATOM   6507  C C   . GLN B 1 286 ? 88.499  143.225 105.974 1.00 100.27 ? 286 GLN B C   1 
ATOM   6508  O O   . GLN B 1 286 ? 88.114  142.876 107.088 1.00 103.37 ? 286 GLN B O   1 
ATOM   6509  C CB  . GLN B 1 286 ? 87.763  145.622 106.480 1.00 99.06  ? 286 GLN B CB  1 
ATOM   6510  C CG  . GLN B 1 286 ? 87.381  147.017 105.953 1.00 100.75 ? 286 GLN B CG  1 
ATOM   6511  C CD  . GLN B 1 286 ? 88.579  147.825 105.478 1.00 104.13 ? 286 GLN B CD  1 
ATOM   6512  O OE1 . GLN B 1 286 ? 88.826  147.996 104.293 1.00 99.57  ? 286 GLN B OE1 1 
ATOM   6513  N NE2 . GLN B 1 286 ? 89.372  148.356 106.377 1.00 105.48 ? 286 GLN B NE2 1 
ATOM   6514  N N   . LEU B 1 287 ? 89.293  142.448 105.229 1.00 90.56  ? 287 LEU B N   1 
ATOM   6515  C CA  . LEU B 1 287 ? 89.658  141.066 105.591 1.00 82.75  ? 287 LEU B CA  1 
ATOM   6516  C C   . LEU B 1 287 ? 90.399  140.946 106.927 1.00 85.31  ? 287 LEU B C   1 
ATOM   6517  O O   . LEU B 1 287 ? 90.283  139.940 107.618 1.00 90.62  ? 287 LEU B O   1 
ATOM   6518  C CB  . LEU B 1 287 ? 90.519  140.431 104.483 1.00 82.54  ? 287 LEU B CB  1 
ATOM   6519  C CG  . LEU B 1 287 ? 89.854  140.239 103.115 1.00 86.95  ? 287 LEU B CG  1 
ATOM   6520  C CD1 . LEU B 1 287 ? 90.852  139.574 102.180 1.00 85.35  ? 287 LEU B CD1 1 
ATOM   6521  C CD2 . LEU B 1 287 ? 88.620  139.353 103.178 1.00 89.02  ? 287 LEU B CD2 1 
ATOM   6522  N N   . GLU B 1 288 ? 91.126  141.994 107.296 1.00 85.61  ? 288 GLU B N   1 
ATOM   6523  C CA  . GLU B 1 288 ? 91.822  142.114 108.570 1.00 84.13  ? 288 GLU B CA  1 
ATOM   6524  C C   . GLU B 1 288 ? 90.954  142.668 109.703 1.00 85.48  ? 288 GLU B C   1 
ATOM   6525  O O   . GLU B 1 288 ? 91.438  142.820 110.815 1.00 93.26  ? 288 GLU B O   1 
ATOM   6526  C CB  . GLU B 1 288 ? 93.051  142.995 108.390 1.00 85.80  ? 288 GLU B CB  1 
ATOM   6527  C CG  . GLU B 1 288 ? 94.023  142.415 107.374 1.00 85.92  ? 288 GLU B CG  1 
ATOM   6528  C CD  . GLU B 1 288 ? 95.315  143.218 107.389 1.00 90.38  ? 288 GLU B CD  1 
ATOM   6529  O OE1 . GLU B 1 288 ? 95.251  144.459 107.283 1.00 97.16  ? 288 GLU B OE1 1 
ATOM   6530  O OE2 . GLU B 1 288 ? 96.399  142.621 107.537 1.00 81.12  ? 288 GLU B OE2 1 
ATOM   6531  N N   . GLU B 1 289 ? 89.680  142.967 109.456 1.00 86.88  ? 289 GLU B N   1 
ATOM   6532  C CA  . GLU B 1 289 ? 88.690  143.271 110.492 1.00 87.36  ? 289 GLU B CA  1 
ATOM   6533  C C   . GLU B 1 289 ? 87.764  142.077 110.771 1.00 92.68  ? 289 GLU B C   1 
ATOM   6534  O O   . GLU B 1 289 ? 86.917  142.143 111.662 1.00 95.31  ? 289 GLU B O   1 
ATOM   6535  C CB  . GLU B 1 289 ? 87.908  144.539 110.128 1.00 91.23  ? 289 GLU B CB  1 
ATOM   6536  C CG  . GLU B 1 289 ? 88.827  145.769 110.043 1.00 95.29  ? 289 GLU B CG  1 
ATOM   6537  C CD  . GLU B 1 289 ? 88.077  147.065 109.696 1.00 96.28  ? 289 GLU B CD  1 
ATOM   6538  O OE1 . GLU B 1 289 ? 86.901  147.231 110.094 1.00 96.65  ? 289 GLU B OE1 1 
ATOM   6539  O OE2 . GLU B 1 289 ? 88.681  147.938 109.035 1.00 93.96  ? 289 GLU B OE2 1 
ATOM   6540  N N   . ILE B 1 290 ? 87.928  140.963 110.051 1.00 88.19  ? 290 ILE B N   1 
ATOM   6541  C CA  . ILE B 1 290 ? 87.227  139.703 110.312 1.00 80.59  ? 290 ILE B CA  1 
ATOM   6542  C C   . ILE B 1 290 ? 87.792  139.088 111.592 1.00 82.23  ? 290 ILE B C   1 
ATOM   6543  O O   . ILE B 1 290 ? 89.001  138.930 111.729 1.00 83.87  ? 290 ILE B O   1 
ATOM   6544  C CB  . ILE B 1 290 ? 87.322  138.740 109.108 1.00 80.69  ? 290 ILE B CB  1 
ATOM   6545  C CG1 . ILE B 1 290 ? 86.712  139.374 107.842 1.00 82.31  ? 290 ILE B CG1 1 
ATOM   6546  C CG2 . ILE B 1 290 ? 86.601  137.425 109.444 1.00 87.94  ? 290 ILE B CG2 1 
ATOM   6547  C CD1 . ILE B 1 290 ? 86.841  138.535 106.571 1.00 85.11  ? 290 ILE B CD1 1 
ATOM   6548  N N   . SER B 1 291 ? 86.921  138.734 112.532 1.00 81.42  ? 291 SER B N   1 
ATOM   6549  C CA  . SER B 1 291 ? 87.283  138.188 113.845 1.00 76.58  ? 291 SER B CA  1 
ATOM   6550  C C   . SER B 1 291 ? 87.016  136.688 113.924 1.00 83.41  ? 291 SER B C   1 
ATOM   6551  O O   . SER B 1 291 ? 85.940  136.230 113.541 1.00 81.95  ? 291 SER B O   1 
ATOM   6552  C CB  . SER B 1 291 ? 86.489  138.894 114.942 1.00 77.14  ? 291 SER B CB  1 
ATOM   6553  O OG  . SER B 1 291 ? 86.800  140.271 114.971 1.00 82.42  ? 291 SER B OG  1 
ATOM   6554  N N   . ASN B 1 292 ? 87.964  135.907 114.438 1.00 75.85  ? 292 ASN B N   1 
ATOM   6555  C CA  . ASN B 1 292 ? 87.731  134.493 114.735 1.00 70.44  ? 292 ASN B CA  1 
ATOM   6556  C C   . ASN B 1 292 ? 86.829  134.314 115.980 1.00 73.49  ? 292 ASN B C   1 
ATOM   6557  O O   . ASN B 1 292 ? 86.360  135.288 116.566 1.00 78.73  ? 292 ASN B O   1 
ATOM   6558  C CB  . ASN B 1 292 ? 89.090  133.776 114.795 1.00 70.97  ? 292 ASN B CB  1 
ATOM   6559  C CG  . ASN B 1 292 ? 89.927  134.049 116.019 1.00 67.21  ? 292 ASN B CG  1 
ATOM   6560  O OD1 . ASN B 1 292 ? 89.517  134.697 116.964 1.00 77.27  ? 292 ASN B OD1 1 
ATOM   6561  N ND2 . ASN B 1 292 ? 91.119  133.525 116.056 1.00 67.54  ? 292 ASN B ND2 1 
ATOM   6562  N N   . HIS B 1 293 ? 86.567  133.082 116.426 1.00 86.51  ? 293 HIS B N   1 
ATOM   6563  C CA  . HIS B 1 293 ? 85.686  132.835 117.578 1.00 86.22  ? 293 HIS B CA  1 
ATOM   6564  C C   . HIS B 1 293 ? 86.248  133.320 118.923 1.00 87.87  ? 293 HIS B C   1 
ATOM   6565  O O   . HIS B 1 293 ? 85.491  133.445 119.882 1.00 92.93  ? 293 HIS B O   1 
ATOM   6566  C CB  . HIS B 1 293 ? 85.333  131.347 117.650 1.00 81.07  ? 293 HIS B CB  1 
ATOM   6567  C CG  . HIS B 1 293 ? 84.538  130.805 116.488 1.00 85.83  ? 293 HIS B CG  1 
ATOM   6568  N ND1 . HIS B 1 293 ? 84.257  129.457 116.298 1.00 92.29  ? 293 HIS B ND1 1 
ATOM   6569  C CD2 . HIS B 1 293 ? 83.921  131.518 115.500 1.00 85.13  ? 293 HIS B CD2 1 
ATOM   6570  C CE1 . HIS B 1 293 ? 83.501  129.380 115.191 1.00 88.68  ? 293 HIS B CE1 1 
ATOM   6571  N NE2 . HIS B 1 293 ? 83.282  130.604 114.696 1.00 85.15  ? 293 HIS B NE2 1 
ATOM   6572  N N   . GLN B 1 294 ? 87.541  133.642 119.011 1.00 81.88  ? 294 GLN B N   1 
ATOM   6573  C CA  . GLN B 1 294 ? 88.140  134.332 120.161 1.00 82.12  ? 294 GLN B CA  1 
ATOM   6574  C C   . GLN B 1 294 ? 88.043  135.867 120.064 1.00 87.80  ? 294 GLN B C   1 
ATOM   6575  O O   . GLN B 1 294 ? 88.563  136.574 120.925 1.00 85.59  ? 294 GLN B O   1 
ATOM   6576  C CB  . GLN B 1 294 ? 89.601  133.899 120.347 1.00 84.26  ? 294 GLN B CB  1 
ATOM   6577  C CG  . GLN B 1 294 ? 89.760  132.387 120.523 1.00 88.36  ? 294 GLN B CG  1 
ATOM   6578  C CD  . GLN B 1 294 ? 91.133  131.969 121.046 1.00 92.26  ? 294 GLN B CD  1 
ATOM   6579  O OE1 . GLN B 1 294 ? 91.911  132.750 121.581 1.00 90.39  ? 294 GLN B OE1 1 
ATOM   6580  N NE2 . GLN B 1 294 ? 91.483  130.711 120.934 1.00 87.52  ? 294 GLN B NE2 1 
ATOM   6581  N N   . GLY B 1 295 ? 87.410  136.406 119.021 1.00 84.54  ? 295 GLY B N   1 
ATOM   6582  C CA  . GLY B 1 295 ? 87.299  137.843 118.769 1.00 79.75  ? 295 GLY B CA  1 
ATOM   6583  C C   . GLY B 1 295 ? 88.563  138.486 118.195 1.00 83.12  ? 295 GLY B C   1 
ATOM   6584  O O   . GLY B 1 295 ? 88.678  139.707 118.191 1.00 90.54  ? 295 GLY B O   1 
ATOM   6585  N N   . LEU B 1 296 ? 89.528  137.695 117.726 1.00 73.54  ? 296 LEU B N   1 
ATOM   6586  C CA  . LEU B 1 296 ? 90.821  138.184 117.256 1.00 66.85  ? 296 LEU B CA  1 
ATOM   6587  C C   . LEU B 1 296 ? 90.801  138.384 115.741 1.00 71.72  ? 296 LEU B C   1 
ATOM   6588  O O   . LEU B 1 296 ? 90.431  137.494 114.982 1.00 75.19  ? 296 LEU B O   1 
ATOM   6589  C CB  . LEU B 1 296 ? 91.942  137.208 117.651 1.00 66.27  ? 296 LEU B CB  1 
ATOM   6590  C CG  . LEU B 1 296 ? 92.042  136.910 119.151 1.00 67.99  ? 296 LEU B CG  1 
ATOM   6591  C CD1 . LEU B 1 296 ? 92.999  135.758 119.388 1.00 71.42  ? 296 LEU B CD1 1 
ATOM   6592  C CD2 . LEU B 1 296 ? 92.561  138.090 119.952 1.00 71.30  ? 296 LEU B CD2 1 
ATOM   6593  N N   . THR B 1 297 ? 91.247  139.548 115.290 1.00 73.82  ? 297 THR B N   1 
ATOM   6594  C CA  . THR B 1 297 ? 91.671  139.791 113.911 1.00 64.06  ? 297 THR B CA  1 
ATOM   6595  C C   . THR B 1 297 ? 93.064  139.193 113.670 1.00 63.74  ? 297 THR B C   1 
ATOM   6596  O O   . THR B 1 297 ? 93.747  138.858 114.637 1.00 66.69  ? 297 THR B O   1 
ATOM   6597  C CB  . THR B 1 297 ? 91.681  141.295 113.644 1.00 60.71  ? 297 THR B CB  1 
ATOM   6598  O OG1 . THR B 1 297 ? 92.563  141.957 114.512 1.00 69.55  ? 297 THR B OG1 1 
ATOM   6599  C CG2 . THR B 1 297 ? 90.311  141.931 113.827 1.00 58.48  ? 297 THR B CG2 1 
ATOM   6600  N N   . PRO B 1 298 ? 93.556  139.070 112.424 1.00 52.09  ? 298 PRO B N   1 
ATOM   6601  C CA  . PRO B 1 298 ? 94.902  138.572 112.157 1.00 52.09  ? 298 PRO B CA  1 
ATOM   6602  C C   . PRO B 1 298 ? 96.029  139.310 112.907 1.00 50.98  ? 298 PRO B C   1 
ATOM   6603  O O   . PRO B 1 298 ? 96.918  138.657 113.439 1.00 56.21  ? 298 PRO B O   1 
ATOM   6604  C CB  . PRO B 1 298 ? 95.066  138.676 110.644 1.00 61.02  ? 298 PRO B CB  1 
ATOM   6605  C CG  . PRO B 1 298 ? 93.646  138.553 110.118 1.00 54.05  ? 298 PRO B CG  1 
ATOM   6606  C CD  . PRO B 1 298 ? 92.833  139.273 111.181 1.00 57.41  ? 298 PRO B CD  1 
ATOM   6607  N N   . LEU B 1 299 ? 95.981  140.641 113.036 1.00 54.58  ? 299 LEU B N   1 
ATOM   6608  C CA  . LEU B 1 299 ? 96.968  141.417 113.803 1.00 57.38  ? 299 LEU B CA  1 
ATOM   6609  C C   . LEU B 1 299 ? 96.923  141.100 115.303 1.00 67.24  ? 299 LEU B C   1 
ATOM   6610  O O   . LEU B 1 299 ? 97.960  140.905 115.931 1.00 69.74  ? 299 LEU B O   1 
ATOM   6611  C CB  . LEU B 1 299 ? 96.753  142.922 113.552 1.00 56.18  ? 299 LEU B CB  1 
ATOM   6612  C CG  . LEU B 1 299 ? 97.710  143.847 114.338 1.00 49.48  ? 299 LEU B CG  1 
ATOM   6613  C CD1 . LEU B 1 299 ? 99.162  143.673 113.933 1.00 57.77  ? 299 LEU B CD1 1 
ATOM   6614  C CD2 . LEU B 1 299 ? 97.343  145.302 114.122 1.00 61.32  ? 299 LEU B CD2 1 
ATOM   6615  N N   . LYS B 1 300 ? 95.724  141.013 115.886 1.00 70.45  ? 300 LYS B N   1 
ATOM   6616  C CA  . LYS B 1 300 ? 95.532  140.655 117.298 1.00 55.05  ? 300 LYS B CA  1 
ATOM   6617  C C   . LYS B 1 300 ? 95.950  139.215 117.584 1.00 60.99  ? 300 LYS B C   1 
ATOM   6618  O O   . LYS B 1 300 ? 96.536  138.945 118.622 1.00 74.73  ? 300 LYS B O   1 
ATOM   6619  C CB  . LYS B 1 300 ? 94.069  140.872 117.691 1.00 62.06  ? 300 LYS B CB  1 
ATOM   6620  C CG  . LYS B 1 300 ? 93.676  142.348 117.764 1.00 55.44  ? 300 LYS B CG  1 
ATOM   6621  C CD  . LYS B 1 300 ? 92.245  142.480 118.282 1.00 57.92  ? 300 LYS B CD  1 
ATOM   6622  C CE  . LYS B 1 300 ? 91.787  143.931 118.211 1.00 64.44  ? 300 LYS B CE  1 
ATOM   6623  N NZ  . LYS B 1 300 ? 90.458  144.116 118.836 1.00 66.28  ? 300 LYS B NZ  1 
ATOM   6624  N N   . LEU B 1 301 ? 95.703  138.290 116.662 1.00 60.57  ? 301 LEU B N   1 
ATOM   6625  C CA  . LEU B 1 301 ? 96.168  136.913 116.757 1.00 65.04  ? 301 LEU B CA  1 
ATOM   6626  C C   . LEU B 1 301 ? 97.695  136.811 116.683 1.00 67.85  ? 301 LEU B C   1 
ATOM   6627  O O   . LEU B 1 301 ? 98.284  136.043 117.432 1.00 72.17  ? 301 LEU B O   1 
ATOM   6628  C CB  . LEU B 1 301 ? 95.472  136.088 115.665 1.00 60.38  ? 301 LEU B CB  1 
ATOM   6629  C CG  . LEU B 1 301 ? 95.819  134.597 115.680 1.00 50.36  ? 301 LEU B CG  1 
ATOM   6630  C CD1 . LEU B 1 301 ? 95.313  133.896 116.931 1.00 57.87  ? 301 LEU B CD1 1 
ATOM   6631  C CD2 . LEU B 1 301 ? 95.173  133.924 114.486 1.00 56.24  ? 301 LEU B CD2 1 
ATOM   6632  N N   . ALA B 1 302 ? 98.367  137.613 115.860 1.00 64.16  ? 302 ALA B N   1 
ATOM   6633  C CA  . ALA B 1 302 ? 99.825  137.627 115.798 1.00 46.81  ? 302 ALA B CA  1 
ATOM   6634  C C   . ALA B 1 302 ? 100.470 138.090 117.117 1.00 62.83  ? 302 ALA B C   1 
ATOM   6635  O O   . ALA B 1 302 ? 101.520 137.578 117.484 1.00 72.14  ? 302 ALA B O   1 
ATOM   6636  C CB  . ALA B 1 302 ? 100.246 138.483 114.604 1.00 44.06  ? 302 ALA B CB  1 
ATOM   6637  N N   . ALA B 1 303 ? 99.820  138.990 117.861 1.00 69.16  ? 303 ALA B N   1 
ATOM   6638  C CA  . ALA B 1 303 ? 100.197 139.424 119.202 1.00 57.75  ? 303 ALA B CA  1 
ATOM   6639  C C   . ALA B 1 303 ? 99.953  138.349 120.273 1.00 68.14  ? 303 ALA B C   1 
ATOM   6640  O O   . ALA B 1 303 ? 100.847 138.064 121.065 1.00 73.68  ? 303 ALA B O   1 
ATOM   6641  C CB  . ALA B 1 303 ? 99.421  140.701 119.514 1.00 58.19  ? 303 ALA B CB  1 
ATOM   6642  N N   . LYS B 1 304 ? 98.786  137.695 120.270 1.00 68.36  ? 304 LYS B N   1 
ATOM   6643  C CA  . LYS B 1 304 ? 98.457  136.648 121.243 1.00 58.28  ? 304 LYS B CA  1 
ATOM   6644  C C   . LYS B 1 304 ? 99.336  135.409 121.087 1.00 67.84  ? 304 LYS B C   1 
ATOM   6645  O O   . LYS B 1 304 ? 99.811  134.857 122.073 1.00 72.79  ? 304 LYS B O   1 
ATOM   6646  C CB  . LYS B 1 304 ? 96.970  136.304 121.140 1.00 60.71  ? 304 LYS B CB  1 
ATOM   6647  C CG  . LYS B 1 304 ? 96.541  135.478 122.352 1.00 76.65  ? 304 LYS B CG  1 
ATOM   6648  C CD  . LYS B 1 304 ? 95.043  135.209 122.339 1.00 77.53  ? 304 LYS B CD  1 
ATOM   6649  C CE  . LYS B 1 304 ? 94.629  134.436 123.590 1.00 75.00  ? 304 LYS B CE  1 
ATOM   6650  N NZ  . LYS B 1 304 ? 93.163  134.223 123.626 1.00 79.10  ? 304 LYS B NZ  1 
ATOM   6651  N N   . GLU B 1 305 ? 99.606  135.003 119.854 1.00 76.41  ? 305 GLU B N   1 
ATOM   6652  C CA  . GLU B 1 305 ? 100.504 133.893 119.521 1.00 71.04  ? 305 GLU B CA  1 
ATOM   6653  C C   . GLU B 1 305 ? 101.994 134.286 119.533 1.00 72.89  ? 305 GLU B C   1 
ATOM   6654  O O   . GLU B 1 305 ? 102.856 133.423 119.407 1.00 74.73  ? 305 GLU B O   1 
ATOM   6655  C CB  . GLU B 1 305 ? 100.084 133.299 118.170 1.00 67.51  ? 305 GLU B CB  1 
ATOM   6656  C CG  . GLU B 1 305 ? 98.662  132.722 118.168 1.00 72.79  ? 305 GLU B CG  1 
ATOM   6657  C CD  . GLU B 1 305 ? 98.482  131.553 119.149 1.00 81.16  ? 305 GLU B CD  1 
ATOM   6658  O OE1 . GLU B 1 305 ? 99.338  130.640 119.168 1.00 83.44  ? 305 GLU B OE1 1 
ATOM   6659  O OE2 . GLU B 1 305 ? 97.477  131.532 119.895 1.00 80.80  ? 305 GLU B OE2 1 
ATOM   6660  N N   . GLY B 1 306 ? 102.324 135.569 119.703 1.00 64.84  ? 306 GLY B N   1 
ATOM   6661  C CA  . GLY B 1 306 ? 103.697 136.051 119.855 1.00 60.32  ? 306 GLY B CA  1 
ATOM   6662  C C   . GLY B 1 306 ? 104.553 135.975 118.600 1.00 61.33  ? 306 GLY B C   1 
ATOM   6663  O O   . GLY B 1 306 ? 105.762 135.793 118.696 1.00 70.80  ? 306 GLY B O   1 
ATOM   6664  N N   . LYS B 1 307 ? 103.955 136.055 117.414 1.00 67.75  ? 307 LYS B N   1 
ATOM   6665  C CA  . LYS B 1 307 ? 104.635 135.876 116.126 1.00 71.25  ? 307 LYS B CA  1 
ATOM   6666  C C   . LYS B 1 307 ? 105.286 137.178 115.665 1.00 76.03  ? 307 LYS B C   1 
ATOM   6667  O O   . LYS B 1 307 ? 104.730 137.858 114.813 1.00 74.27  ? 307 LYS B O   1 
ATOM   6668  C CB  . LYS B 1 307 ? 103.642 135.326 115.087 1.00 61.65  ? 307 LYS B CB  1 
ATOM   6669  C CG  . LYS B 1 307 ? 102.890 134.053 115.478 1.00 69.65  ? 307 LYS B CG  1 
ATOM   6670  C CD  . LYS B 1 307 ? 103.834 132.909 115.856 1.00 70.03  ? 307 LYS B CD  1 
ATOM   6671  C CE  . LYS B 1 307 ? 103.079 131.604 116.095 1.00 67.05  ? 307 LYS B CE  1 
ATOM   6672  N NZ  . LYS B 1 307 ? 102.536 131.056 114.836 1.00 70.21  ? 307 LYS B NZ  1 
ATOM   6673  N N   . ILE B 1 308 ? 106.439 137.564 116.210 1.00 79.20  ? 308 ILE B N   1 
ATOM   6674  C CA  . ILE B 1 308 ? 106.988 138.924 116.029 1.00 69.61  ? 308 ILE B CA  1 
ATOM   6675  C C   . ILE B 1 308 ? 107.156 139.310 114.557 1.00 69.38  ? 308 ILE B C   1 
ATOM   6676  O O   . ILE B 1 308 ? 106.868 140.439 114.197 1.00 78.62  ? 308 ILE B O   1 
ATOM   6677  C CB  . ILE B 1 308 ? 108.337 139.130 116.753 1.00 73.81  ? 308 ILE B CB  1 
ATOM   6678  C CG1 . ILE B 1 308 ? 108.316 138.711 118.227 1.00 75.52  ? 308 ILE B CG1 1 
ATOM   6679  C CG2 . ILE B 1 308 ? 108.761 140.610 116.688 1.00 73.72  ? 308 ILE B CG2 1 
ATOM   6680  C CD1 . ILE B 1 308 ? 109.730 138.404 118.725 1.00 82.24  ? 308 ILE B CD1 1 
ATOM   6681  N N   . GLU B 1 309 ? 107.605 138.407 113.687 1.00 77.67  ? 309 GLU B N   1 
ATOM   6682  C CA  . GLU B 1 309 ? 107.944 138.769 112.306 1.00 77.85  ? 309 GLU B CA  1 
ATOM   6683  C C   . GLU B 1 309 ? 106.724 139.147 111.462 1.00 76.16  ? 309 GLU B C   1 
ATOM   6684  O O   . GLU B 1 309 ? 106.714 140.196 110.823 1.00 76.94  ? 309 GLU B O   1 
ATOM   6685  C CB  . GLU B 1 309 ? 108.707 137.624 111.627 1.00 82.19  ? 309 GLU B CB  1 
ATOM   6686  C CG  . GLU B 1 309 ? 109.989 137.176 112.344 1.00 85.28  ? 309 GLU B CG  1 
ATOM   6687  C CD  . GLU B 1 309 ? 111.003 138.304 112.580 1.00 87.52  ? 309 GLU B CD  1 
ATOM   6688  O OE1 . GLU B 1 309 ? 110.957 139.337 111.873 1.00 85.71  ? 309 GLU B OE1 1 
ATOM   6689  O OE2 . GLU B 1 309 ? 111.860 138.173 113.481 1.00 85.86  ? 309 GLU B OE2 1 
ATOM   6690  N N   . ILE B 1 310 ? 105.668 138.332 111.477 1.00 68.10  ? 310 ILE B N   1 
ATOM   6691  C CA  . ILE B 1 310 ? 104.404 138.668 110.816 1.00 64.45  ? 310 ILE B CA  1 
ATOM   6692  C C   . ILE B 1 310 ? 103.664 139.789 111.551 1.00 70.81  ? 310 ILE B C   1 
ATOM   6693  O O   . ILE B 1 310 ? 103.048 140.624 110.900 1.00 72.43  ? 310 ILE B O   1 
ATOM   6694  C CB  . ILE B 1 310 ? 103.548 137.408 110.562 1.00 65.48  ? 310 ILE B CB  1 
ATOM   6695  C CG1 . ILE B 1 310 ? 102.269 137.665 109.737 1.00 72.32  ? 310 ILE B CG1 1 
ATOM   6696  C CG2 . ILE B 1 310 ? 103.131 136.718 111.864 1.00 67.34  ? 310 ILE B CG2 1 
ATOM   6697  C CD1 . ILE B 1 310 ? 102.521 138.221 108.332 1.00 75.07  ? 310 ILE B CD1 1 
ATOM   6698  N N   . PHE B 1 311 ? 103.766 139.889 112.881 1.00 72.85  ? 311 PHE B N   1 
ATOM   6699  C CA  . PHE B 1 311 ? 103.209 140.999 113.658 1.00 60.87  ? 311 PHE B CA  1 
ATOM   6700  C C   . PHE B 1 311 ? 103.815 142.343 113.244 1.00 63.63  ? 311 PHE B C   1 
ATOM   6701  O O   . PHE B 1 311 ? 103.092 143.236 112.823 1.00 66.20  ? 311 PHE B O   1 
ATOM   6702  C CB  . PHE B 1 311 ? 103.424 140.733 115.151 1.00 54.92  ? 311 PHE B CB  1 
ATOM   6703  C CG  . PHE B 1 311 ? 102.949 141.853 116.045 1.00 62.62  ? 311 PHE B CG  1 
ATOM   6704  C CD1 . PHE B 1 311 ? 101.578 142.138 116.130 1.00 62.92  ? 311 PHE B CD1 1 
ATOM   6705  C CD2 . PHE B 1 311 ? 103.868 142.624 116.777 1.00 63.78  ? 311 PHE B CD2 1 
ATOM   6706  C CE1 . PHE B 1 311 ? 101.125 143.197 116.919 1.00 58.24  ? 311 PHE B CE1 1 
ATOM   6707  C CE2 . PHE B 1 311 ? 103.417 143.688 117.566 1.00 63.66  ? 311 PHE B CE2 1 
ATOM   6708  C CZ  . PHE B 1 311 ? 102.049 143.976 117.627 1.00 65.50  ? 311 PHE B CZ  1 
ATOM   6709  N N   . ARG B 1 312 ? 105.148 142.461 113.275 1.00 66.67  ? 312 ARG B N   1 
ATOM   6710  C CA  . ARG B 1 312 ? 105.914 143.618 112.805 1.00 58.49  ? 312 ARG B CA  1 
ATOM   6711  C C   . ARG B 1 312 ? 105.560 143.981 111.378 1.00 67.40  ? 312 ARG B C   1 
ATOM   6712  O O   . ARG B 1 312 ? 105.340 145.152 111.097 1.00 75.74  ? 312 ARG B O   1 
ATOM   6713  C CB  . ARG B 1 312 ? 107.409 143.298 112.929 1.00 63.19  ? 312 ARG B CB  1 
ATOM   6714  C CG  . ARG B 1 312 ? 108.309 144.353 112.275 1.00 65.41  ? 312 ARG B CG  1 
ATOM   6715  C CD  . ARG B 1 312 ? 109.742 144.322 112.798 1.00 73.05  ? 312 ARG B CD  1 
ATOM   6716  N NE  . ARG B 1 312 ? 110.368 142.989 112.753 1.00 78.77  ? 312 ARG B NE  1 
ATOM   6717  C CZ  . ARG B 1 312 ? 111.445 142.634 113.429 1.00 79.62  ? 312 ARG B CZ  1 
ATOM   6718  N NH1 . ARG B 1 312 ? 111.934 141.440 113.330 1.00 74.59  ? 312 ARG B NH1 1 
ATOM   6719  N NH2 . ARG B 1 312 ? 112.071 143.460 114.212 1.00 77.07  ? 312 ARG B NH2 1 
ATOM   6720  N N   . HIS B 1 313 ? 105.482 143.004 110.480 1.00 64.93  ? 313 HIS B N   1 
ATOM   6721  C CA  . HIS B 1 313 ? 105.127 143.266 109.095 1.00 53.76  ? 313 HIS B CA  1 
ATOM   6722  C C   . HIS B 1 313 ? 103.737 143.871 108.962 1.00 62.15  ? 313 HIS B C   1 
ATOM   6723  O O   . HIS B 1 313 ? 103.622 144.934 108.371 1.00 75.48  ? 313 HIS B O   1 
ATOM   6724  C CB  . HIS B 1 313 ? 105.252 142.002 108.259 1.00 67.91  ? 313 HIS B CB  1 
ATOM   6725  C CG  . HIS B 1 313 ? 104.823 142.268 106.843 1.00 74.71  ? 313 HIS B CG  1 
ATOM   6726  N ND1 . HIS B 1 313 ? 105.540 143.025 105.916 1.00 67.33  ? 313 HIS B ND1 1 
ATOM   6727  C CD2 . HIS B 1 313 ? 103.614 141.936 106.313 1.00 68.19  ? 313 HIS B CD2 1 
ATOM   6728  C CE1 . HIS B 1 313 ? 104.745 143.120 104.840 1.00 65.28  ? 313 HIS B CE1 1 
ATOM   6729  N NE2 . HIS B 1 313 ? 103.587 142.485 105.058 1.00 60.32  ? 313 HIS B NE2 1 
ATOM   6730  N N   . ILE B 1 314 ? 102.687 143.268 109.527 1.00 62.98  ? 314 ILE B N   1 
ATOM   6731  C CA  . ILE B 1 314 ? 101.324 143.811 109.441 1.00 63.52  ? 314 ILE B CA  1 
ATOM   6732  C C   . ILE B 1 314 ? 101.283 145.226 110.023 1.00 57.93  ? 314 ILE B C   1 
ATOM   6733  O O   . ILE B 1 314 ? 100.791 146.153 109.390 1.00 68.08  ? 314 ILE B O   1 
ATOM   6734  C CB  . ILE B 1 314 ? 100.307 142.890 110.154 1.00 68.48  ? 314 ILE B CB  1 
ATOM   6735  C CG1 . ILE B 1 314 ? 100.203 141.501 109.492 1.00 61.78  ? 314 ILE B CG1 1 
ATOM   6736  C CG2 . ILE B 1 314 ? 98.910  143.537 110.163 1.00 63.16  ? 314 ILE B CG2 1 
ATOM   6737  C CD1 . ILE B 1 314 ? 99.563  140.449 110.402 1.00 58.04  ? 314 ILE B CD1 1 
ATOM   6738  N N   . LEU B 1 315 ? 101.843 145.400 111.217 1.00 54.75  ? 315 LEU B N   1 
ATOM   6739  C CA  . LEU B 1 315 ? 101.824 146.625 112.009 1.00 56.71  ? 315 LEU B CA  1 
ATOM   6740  C C   . LEU B 1 315 ? 102.462 147.829 111.292 1.00 60.42  ? 315 LEU B C   1 
ATOM   6741  O O   . LEU B 1 315 ? 101.968 148.947 111.405 1.00 58.37  ? 315 LEU B O   1 
ATOM   6742  C CB  . LEU B 1 315 ? 102.560 146.258 113.304 1.00 55.72  ? 315 LEU B CB  1 
ATOM   6743  C CG  . LEU B 1 315 ? 102.630 147.340 114.370 1.00 55.74  ? 315 LEU B CG  1 
ATOM   6744  C CD1 . LEU B 1 315 ? 101.293 147.437 115.095 1.00 60.48  ? 315 LEU B CD1 1 
ATOM   6745  C CD2 . LEU B 1 315 ? 103.734 146.979 115.353 1.00 53.29  ? 315 LEU B CD2 1 
ATOM   6746  N N   . GLN B 1 316 ? 103.539 147.606 110.545 1.00 66.47  ? 316 GLN B N   1 
ATOM   6747  C CA  . GLN B 1 316 ? 104.338 148.634 109.876 1.00 55.56  ? 316 GLN B CA  1 
ATOM   6748  C C   . GLN B 1 316 ? 104.150 148.674 108.350 1.00 56.46  ? 316 GLN B C   1 
ATOM   6749  O O   . GLN B 1 316 ? 104.910 149.338 107.654 1.00 64.01  ? 316 GLN B O   1 
ATOM   6750  C CB  . GLN B 1 316 ? 105.816 148.425 110.234 1.00 54.70  ? 316 GLN B CB  1 
ATOM   6751  C CG  . GLN B 1 316 ? 106.079 148.411 111.744 1.00 64.50  ? 316 GLN B CG  1 
ATOM   6752  C CD  . GLN B 1 316 ? 107.553 148.263 112.090 1.00 64.88  ? 316 GLN B CD  1 
ATOM   6753  O OE1 . GLN B 1 316 ? 108.394 147.912 111.278 1.00 68.29  ? 316 GLN B OE1 1 
ATOM   6754  N NE2 . GLN B 1 316 ? 107.924 148.533 113.316 1.00 66.15  ? 316 GLN B NE2 1 
ATOM   6755  N N   . ARG B 1 317 ? 103.171 147.953 107.805 1.00 62.04  ? 317 ARG B N   1 
ATOM   6756  C CA  . ARG B 1 317 ? 103.003 147.716 106.365 1.00 63.86  ? 317 ARG B CA  1 
ATOM   6757  C C   . ARG B 1 317 ? 102.769 148.992 105.566 1.00 72.51  ? 317 ARG B C   1 
ATOM   6758  O O   . ARG B 1 317 ? 101.872 149.761 105.896 1.00 77.90  ? 317 ARG B O   1 
ATOM   6759  C CB  . ARG B 1 317 ? 101.829 146.754 106.199 1.00 60.09  ? 317 ARG B CB  1 
ATOM   6760  C CG  . ARG B 1 317 ? 101.704 146.190 104.785 1.00 67.35  ? 317 ARG B CG  1 
ATOM   6761  C CD  . ARG B 1 317 ? 100.641 145.095 104.782 1.00 72.03  ? 317 ARG B CD  1 
ATOM   6762  N NE  . ARG B 1 317 ? 99.327  145.639 105.152 1.00 71.96  ? 317 ARG B NE  1 
ATOM   6763  C CZ  . ARG B 1 317 ? 98.437  145.119 105.962 1.00 66.89  ? 317 ARG B CZ  1 
ATOM   6764  N NH1 . ARG B 1 317 ? 97.355  145.774 106.213 1.00 60.17  ? 317 ARG B NH1 1 
ATOM   6765  N NH2 . ARG B 1 317 ? 98.583  143.949 106.489 1.00 70.51  ? 317 ARG B NH2 1 
ATOM   6766  N N   . GLU B 1 318 ? 103.498 149.182 104.473 1.00 76.44  ? 318 GLU B N   1 
ATOM   6767  C CA  . GLU B 1 318 ? 103.374 150.327 103.569 1.00 72.94  ? 318 GLU B CA  1 
ATOM   6768  C C   . GLU B 1 318 ? 103.381 149.870 102.106 1.00 81.31  ? 318 GLU B C   1 
ATOM   6769  O O   . GLU B 1 318 ? 104.226 149.063 101.719 1.00 77.91  ? 318 GLU B O   1 
ATOM   6770  C CB  . GLU B 1 318 ? 104.515 151.309 103.870 1.00 78.10  ? 318 GLU B CB  1 
ATOM   6771  C CG  . GLU B 1 318 ? 104.457 152.611 103.060 1.00 83.41  ? 318 GLU B CG  1 
ATOM   6772  C CD  . GLU B 1 318 ? 105.468 153.649 103.566 1.00 85.16  ? 318 GLU B CD  1 
ATOM   6773  O OE1 . GLU B 1 318 ? 106.570 153.259 104.006 1.00 87.02  ? 318 GLU B OE1 1 
ATOM   6774  O OE2 . GLU B 1 318 ? 105.193 154.871 103.486 1.00 84.73  ? 318 GLU B OE2 1 
ATOM   6775  N N   . PHE B 1 319 ? 102.480 150.407 101.283 1.00 92.69  ? 319 PHE B N   1 
ATOM   6776  C CA  . PHE B 1 319 ? 102.379 150.139 99.846  1.00 84.22  ? 319 PHE B CA  1 
ATOM   6777  C C   . PHE B 1 319 ? 102.224 151.440 99.045  1.00 89.26  ? 319 PHE B C   1 
ATOM   6778  O O   . PHE B 1 319 ? 101.788 152.462 99.571  1.00 89.18  ? 319 PHE B O   1 
ATOM   6779  C CB  . PHE B 1 319 ? 101.181 149.227 99.554  1.00 80.64  ? 319 PHE B CB  1 
ATOM   6780  C CG  . PHE B 1 319 ? 101.204 147.835 100.144 1.00 85.90  ? 319 PHE B CG  1 
ATOM   6781  C CD1 . PHE B 1 319 ? 102.232 146.931 99.823  1.00 90.44  ? 319 PHE B CD1 1 
ATOM   6782  C CD2 . PHE B 1 319 ? 100.142 147.413 100.947 1.00 84.74  ? 319 PHE B CD2 1 
ATOM   6783  C CE1 . PHE B 1 319 ? 102.186 145.612 100.310 1.00 88.60  ? 319 PHE B CE1 1 
ATOM   6784  C CE2 . PHE B 1 319 ? 100.084 146.092 101.416 1.00 84.03  ? 319 PHE B CE2 1 
ATOM   6785  C CZ  . PHE B 1 319 ? 101.107 145.190 101.100 1.00 86.64  ? 319 PHE B CZ  1 
ATOM   6786  N N   . SER B 1 320 ? 102.522 151.382 97.748  1.00 111.39 ? 320 SER B N   1 
ATOM   6787  C CA  . SER B 1 320 ? 102.357 152.478 96.788  1.00 112.20 ? 320 SER B CA  1 
ATOM   6788  C C   . SER B 1 320 ? 101.453 152.065 95.621  1.00 113.00 ? 320 SER B C   1 
ATOM   6789  O O   . SER B 1 320 ? 101.315 150.883 95.302  1.00 110.26 ? 320 SER B O   1 
ATOM   6790  C CB  . SER B 1 320 ? 103.723 152.962 96.294  1.00 108.90 ? 320 SER B CB  1 
ATOM   6791  O OG  . SER B 1 320 ? 104.407 151.929 95.610  1.00 110.02 ? 320 SER B OG  1 
ATOM   6792  N N   . GLY B 1 321 ? 100.791 153.033 94.990  1.00 107.71 ? 321 GLY B N   1 
ATOM   6793  C CA  . GLY B 1 321 ? 99.899  152.767 93.860  1.00 106.63 ? 321 GLY B CA  1 
ATOM   6794  C C   . GLY B 1 321 ? 98.549  152.172 94.289  1.00 108.95 ? 321 GLY B C   1 
ATOM   6795  O O   . GLY B 1 321 ? 97.976  152.654 95.270  1.00 110.26 ? 321 GLY B O   1 
ATOM   6796  N N   . PRO B 1 322 ? 98.004  151.155 93.589  1.00 109.84 ? 322 PRO B N   1 
ATOM   6797  C CA  . PRO B 1 322 ? 96.649  150.640 93.807  1.00 109.59 ? 322 PRO B CA  1 
ATOM   6798  C C   . PRO B 1 322 ? 96.345  150.194 95.243  1.00 107.78 ? 322 PRO B C   1 
ATOM   6799  O O   . PRO B 1 322 ? 95.217  150.328 95.711  1.00 106.29 ? 322 PRO B O   1 
ATOM   6800  C CB  . PRO B 1 322 ? 96.520  149.443 92.858  1.00 109.17 ? 322 PRO B CB  1 
ATOM   6801  C CG  . PRO B 1 322 ? 97.493  149.757 91.732  1.00 106.48 ? 322 PRO B CG  1 
ATOM   6802  C CD  . PRO B 1 322 ? 98.616  150.499 92.443  1.00 107.60 ? 322 PRO B CD  1 
ATOM   6803  N N   . TYR B 1 323 ? 97.372  149.706 95.937  1.00 93.97  ? 323 TYR B N   1 
ATOM   6804  C CA  . TYR B 1 323 ? 97.285  149.065 97.241  1.00 95.23  ? 323 TYR B CA  1 
ATOM   6805  C C   . TYR B 1 323 ? 97.563  149.987 98.432  1.00 93.23  ? 323 TYR B C   1 
ATOM   6806  O O   . TYR B 1 323 ? 97.620  149.508 99.559  1.00 97.11  ? 323 TYR B O   1 
ATOM   6807  C CB  . TYR B 1 323 ? 98.222  147.849 97.216  1.00 100.69 ? 323 TYR B CB  1 
ATOM   6808  C CG  . TYR B 1 323 ? 97.937  146.888 96.077  1.00 96.90  ? 323 TYR B CG  1 
ATOM   6809  C CD1 . TYR B 1 323 ? 96.620  146.454 95.821  1.00 96.31  ? 323 TYR B CD1 1 
ATOM   6810  C CD2 . TYR B 1 323 ? 98.987  146.452 95.250  1.00 94.79  ? 323 TYR B CD2 1 
ATOM   6811  C CE1 . TYR B 1 323 ? 96.346  145.618 94.724  1.00 94.85  ? 323 TYR B CE1 1 
ATOM   6812  C CE2 . TYR B 1 323 ? 98.718  145.608 94.157  1.00 98.54  ? 323 TYR B CE2 1 
ATOM   6813  C CZ  . TYR B 1 323 ? 97.398  145.200 93.887  1.00 98.17  ? 323 TYR B CZ  1 
ATOM   6814  O OH  . TYR B 1 323 ? 97.138  144.400 92.824  1.00 96.58  ? 323 TYR B OH  1 
ATOM   6815  N N   . GLN B 1 324 ? 97.702  151.302 98.246  1.00 92.57  ? 324 GLN B N   1 
ATOM   6816  C CA  . GLN B 1 324 ? 97.987  152.214 99.357  1.00 93.37  ? 324 GLN B CA  1 
ATOM   6817  C C   . GLN B 1 324 ? 97.013  152.086 100.558 1.00 93.55  ? 324 GLN B C   1 
ATOM   6818  O O   . GLN B 1 324 ? 97.514  152.033 101.678 1.00 92.85  ? 324 GLN B O   1 
ATOM   6819  C CB  . GLN B 1 324 ? 98.145  153.652 98.836  1.00 91.33  ? 324 GLN B CB  1 
ATOM   6820  C CG  . GLN B 1 324 ? 98.509  154.642 99.947  1.00 95.55  ? 324 GLN B CG  1 
ATOM   6821  C CD  . GLN B 1 324 ? 98.883  156.023 99.419  1.00 96.39  ? 324 GLN B CD  1 
ATOM   6822  O OE1 . GLN B 1 324 ? 98.378  156.498 98.421  1.00 95.87  ? 324 GLN B OE1 1 
ATOM   6823  N NE2 . GLN B 1 324 ? 99.775  156.728 100.058 1.00 94.68  ? 324 GLN B NE2 1 
ATOM   6824  N N   . PRO B 1 325 ? 95.680  151.945 100.401 1.00 88.38  ? 325 PRO B N   1 
ATOM   6825  C CA  . PRO B 1 325 ? 94.740  151.742 101.506 1.00 88.71  ? 325 PRO B CA  1 
ATOM   6826  C C   . PRO B 1 325 ? 94.954  150.469 102.337 1.00 86.62  ? 325 PRO B C   1 
ATOM   6827  O O   . PRO B 1 325 ? 94.463  150.385 103.456 1.00 89.31  ? 325 PRO B O   1 
ATOM   6828  C CB  . PRO B 1 325 ? 93.350  151.721 100.868 1.00 87.59  ? 325 PRO B CB  1 
ATOM   6829  C CG  . PRO B 1 325 ? 93.529  152.551 99.609  1.00 88.74  ? 325 PRO B CG  1 
ATOM   6830  C CD  . PRO B 1 325 ? 94.937  152.178 99.172  1.00 85.54  ? 325 PRO B CD  1 
ATOM   6831  N N   . LEU B 1 326 ? 95.691  149.488 101.809 1.00 82.88  ? 326 LEU B N   1 
ATOM   6832  C CA  . LEU B 1 326 ? 96.106  148.299 102.550 1.00 81.48  ? 326 LEU B CA  1 
ATOM   6833  C C   . LEU B 1 326 ? 97.301  148.583 103.473 1.00 83.38  ? 326 LEU B C   1 
ATOM   6834  O O   . LEU B 1 326 ? 97.688  147.718 104.250 1.00 83.24  ? 326 LEU B O   1 
ATOM   6835  C CB  . LEU B 1 326 ? 96.412  147.142 101.581 1.00 80.38  ? 326 LEU B CB  1 
ATOM   6836  C CG  . LEU B 1 326 ? 95.293  146.780 100.596 1.00 78.88  ? 326 LEU B CG  1 
ATOM   6837  C CD1 . LEU B 1 326 ? 95.786  145.669 99.685  1.00 82.14  ? 326 LEU B CD1 1 
ATOM   6838  C CD2 . LEU B 1 326 ? 94.031  146.311 101.304 1.00 79.38  ? 326 LEU B CD2 1 
ATOM   6839  N N   . SER B 1 327 ? 97.906  149.769 103.422 1.00 79.70  ? 327 SER B N   1 
ATOM   6840  C CA  . SER B 1 327 ? 98.956  150.180 104.357 1.00 76.74  ? 327 SER B CA  1 
ATOM   6841  C C   . SER B 1 327 ? 98.404  150.386 105.766 1.00 75.60  ? 327 SER B C   1 
ATOM   6842  O O   . SER B 1 327 ? 97.264  150.814 105.947 1.00 71.05  ? 327 SER B O   1 
ATOM   6843  C CB  . SER B 1 327 ? 99.617  151.486 103.926 1.00 70.26  ? 327 SER B CB  1 
ATOM   6844  O OG  . SER B 1 327 ? 100.010 151.444 102.578 1.00 69.84  ? 327 SER B OG  1 
ATOM   6845  N N   . ARG B 1 328 ? 99.248  150.146 106.770 1.00 70.08  ? 328 ARG B N   1 
ATOM   6846  C CA  . ARG B 1 328 ? 99.092  150.676 108.128 1.00 63.43  ? 328 ARG B CA  1 
ATOM   6847  C C   . ARG B 1 328 ? 100.048 151.830 108.421 1.00 69.77  ? 328 ARG B C   1 
ATOM   6848  O O   . ARG B 1 328 ? 99.783  152.597 109.329 1.00 84.99  ? 328 ARG B O   1 
ATOM   6849  C CB  . ARG B 1 328 ? 99.275  149.561 109.162 1.00 63.15  ? 328 ARG B CB  1 
ATOM   6850  C CG  . ARG B 1 328 ? 98.159  148.515 109.125 1.00 63.99  ? 328 ARG B CG  1 
ATOM   6851  C CD  . ARG B 1 328 ? 98.158  147.666 110.400 1.00 71.03  ? 328 ARG B CD  1 
ATOM   6852  N NE  . ARG B 1 328 ? 97.618  148.405 111.554 1.00 68.65  ? 328 ARG B NE  1 
ATOM   6853  C CZ  . ARG B 1 328 ? 96.385  148.370 112.003 1.00 70.82  ? 328 ARG B CZ  1 
ATOM   6854  N NH1 . ARG B 1 328 ? 96.027  149.166 112.957 1.00 72.88  ? 328 ARG B NH1 1 
ATOM   6855  N NH2 . ARG B 1 328 ? 95.487  147.577 111.510 1.00 70.40  ? 328 ARG B NH2 1 
ATOM   6856  N N   . LYS B 1 329 ? 101.139 151.975 107.671 1.00 59.74  ? 329 LYS B N   1 
ATOM   6857  C CA  . LYS B 1 329 ? 102.126 153.058 107.760 1.00 54.97  ? 329 LYS B CA  1 
ATOM   6858  C C   . LYS B 1 329 ? 102.072 153.917 106.506 1.00 61.48  ? 329 LYS B C   1 
ATOM   6859  O O   . LYS B 1 329 ? 102.142 153.387 105.405 1.00 75.22  ? 329 LYS B O   1 
ATOM   6860  C CB  . LYS B 1 329 ? 103.506 152.422 107.926 1.00 59.57  ? 329 LYS B CB  1 
ATOM   6861  C CG  . LYS B 1 329 ? 104.680 153.404 107.962 1.00 57.47  ? 329 LYS B CG  1 
ATOM   6862  C CD  . LYS B 1 329 ? 105.989 152.616 107.898 1.00 59.91  ? 329 LYS B CD  1 
ATOM   6863  C CE  . LYS B 1 329 ? 107.193 153.545 107.992 1.00 66.45  ? 329 LYS B CE  1 
ATOM   6864  N NZ  . LYS B 1 329 ? 108.463 152.803 107.815 1.00 64.85  ? 329 LYS B NZ  1 
ATOM   6865  N N   . PHE B 1 330 ? 102.011 155.232 106.657 1.00 65.44  ? 330 PHE B N   1 
ATOM   6866  C CA  . PHE B 1 330 ? 102.058 156.189 105.554 1.00 66.30  ? 330 PHE B CA  1 
ATOM   6867  C C   . PHE B 1 330 ? 103.215 157.164 105.766 1.00 71.80  ? 330 PHE B C   1 
ATOM   6868  O O   . PHE B 1 330 ? 103.172 157.943 106.712 1.00 76.23  ? 330 PHE B O   1 
ATOM   6869  C CB  . PHE B 1 330 ? 100.715 156.930 105.474 1.00 63.24  ? 330 PHE B CB  1 
ATOM   6870  C CG  . PHE B 1 330 ? 99.506  156.023 105.416 1.00 69.94  ? 330 PHE B CG  1 
ATOM   6871  C CD1 . PHE B 1 330 ? 98.909  155.567 106.606 1.00 71.60  ? 330 PHE B CD1 1 
ATOM   6872  C CD2 . PHE B 1 330 ? 98.985  155.613 104.176 1.00 68.42  ? 330 PHE B CD2 1 
ATOM   6873  C CE1 . PHE B 1 330 ? 97.819  154.692 106.559 1.00 70.83  ? 330 PHE B CE1 1 
ATOM   6874  C CE2 . PHE B 1 330 ? 97.878  154.757 104.127 1.00 69.24  ? 330 PHE B CE2 1 
ATOM   6875  C CZ  . PHE B 1 330 ? 97.303  154.290 105.318 1.00 75.42  ? 330 PHE B CZ  1 
ATOM   6876  N N   . THR B 1 331 ? 104.239 157.166 104.917 1.00 77.85  ? 331 THR B N   1 
ATOM   6877  C CA  . THR B 1 331 ? 105.300 158.183 104.990 1.00 73.69  ? 331 THR B CA  1 
ATOM   6878  C C   . THR B 1 331 ? 104.728 159.557 104.649 1.00 70.69  ? 331 THR B C   1 
ATOM   6879  O O   . THR B 1 331 ? 104.209 159.763 103.556 1.00 75.83  ? 331 THR B O   1 
ATOM   6880  C CB  . THR B 1 331 ? 106.477 157.862 104.064 1.00 78.69  ? 331 THR B CB  1 
ATOM   6881  O OG1 . THR B 1 331 ? 107.029 156.605 104.375 1.00 80.96  ? 331 THR B OG1 1 
ATOM   6882  C CG2 . THR B 1 331 ? 107.609 158.873 104.221 1.00 75.64  ? 331 THR B CG2 1 
ATOM   6883  N N   . GLU B 1 332 ? 104.812 160.511 105.572 1.00 73.33  ? 332 GLU B N   1 
ATOM   6884  C CA  . GLU B 1 332 ? 104.337 161.881 105.396 1.00 75.72  ? 332 GLU B CA  1 
ATOM   6885  C C   . GLU B 1 332 ? 105.360 162.731 104.637 1.00 80.85  ? 332 GLU B C   1 
ATOM   6886  O O   . GLU B 1 332 ? 105.030 163.372 103.639 1.00 79.33  ? 332 GLU B O   1 
ATOM   6887  C CB  . GLU B 1 332 ? 104.023 162.486 106.771 1.00 72.89  ? 332 GLU B CB  1 
ATOM   6888  C CG  . GLU B 1 332 ? 103.477 163.908 106.632 1.00 80.28  ? 332 GLU B CG  1 
ATOM   6889  C CD  . GLU B 1 332 ? 103.183 164.574 107.974 1.00 88.18  ? 332 GLU B CD  1 
ATOM   6890  O OE1 . GLU B 1 332 ? 102.682 163.903 108.899 1.00 89.63  ? 332 GLU B OE1 1 
ATOM   6891  O OE2 . GLU B 1 332 ? 103.413 165.795 108.101 1.00 86.34  ? 332 GLU B OE2 1 
ATOM   6892  N N   . TRP B 1 333 ? 106.612 162.717 105.095 1.00 75.72  ? 333 TRP B N   1 
ATOM   6893  C CA  . TRP B 1 333 ? 107.757 163.286 104.390 1.00 69.12  ? 333 TRP B CA  1 
ATOM   6894  C C   . TRP B 1 333 ? 109.045 162.565 104.771 1.00 69.11  ? 333 TRP B C   1 
ATOM   6895  O O   . TRP B 1 333 ? 109.146 161.919 105.809 1.00 76.17  ? 333 TRP B O   1 
ATOM   6896  C CB  . TRP B 1 333 ? 107.852 164.806 104.598 1.00 68.11  ? 333 TRP B CB  1 
ATOM   6897  C CG  . TRP B 1 333 ? 108.041 165.340 105.986 1.00 68.38  ? 333 TRP B CG  1 
ATOM   6898  C CD1 . TRP B 1 333 ? 107.065 165.893 106.735 1.00 68.47  ? 333 TRP B CD1 1 
ATOM   6899  C CD2 . TRP B 1 333 ? 109.261 165.457 106.784 1.00 74.00  ? 333 TRP B CD2 1 
ATOM   6900  N NE1 . TRP B 1 333 ? 107.588 166.340 107.927 1.00 69.03  ? 333 TRP B NE1 1 
ATOM   6901  C CE2 . TRP B 1 333 ? 108.941 166.115 108.003 1.00 69.90  ? 333 TRP B CE2 1 
ATOM   6902  C CE3 . TRP B 1 333 ? 110.614 165.103 106.601 1.00 77.88  ? 333 TRP B CE3 1 
ATOM   6903  C CZ2 . TRP B 1 333 ? 109.901 166.400 108.979 1.00 66.92  ? 333 TRP B CZ2 1 
ATOM   6904  C CZ3 . TRP B 1 333 ? 111.581 165.361 107.588 1.00 69.62  ? 333 TRP B CZ3 1 
ATOM   6905  C CH2 . TRP B 1 333 ? 111.231 166.017 108.772 1.00 68.74  ? 333 TRP B CH2 1 
ATOM   6906  N N   . CYS B 1 334 ? 110.045 162.675 103.912 1.00 77.58  ? 334 CYS B N   1 
ATOM   6907  C CA  . CYS B 1 334 ? 111.388 162.162 104.124 1.00 77.52  ? 334 CYS B CA  1 
ATOM   6908  C C   . CYS B 1 334 ? 112.404 163.216 103.674 1.00 82.08  ? 334 CYS B C   1 
ATOM   6909  O O   . CYS B 1 334 ? 112.254 163.808 102.600 1.00 86.72  ? 334 CYS B O   1 
ATOM   6910  C CB  . CYS B 1 334 ? 111.517 160.841 103.364 1.00 82.34  ? 334 CYS B CB  1 
ATOM   6911  S SG  . CYS B 1 334 ? 113.184 160.168 103.538 1.00 93.31  ? 334 CYS B SG  1 
ATOM   6912  N N   . TYR B 1 335 ? 113.421 163.471 104.491 1.00 73.79  ? 335 TYR B N   1 
ATOM   6913  C CA  . TYR B 1 335 ? 114.450 164.471 104.223 1.00 75.48  ? 335 TYR B CA  1 
ATOM   6914  C C   . TYR B 1 335 ? 115.764 164.066 104.885 1.00 74.68  ? 335 TYR B C   1 
ATOM   6915  O O   . TYR B 1 335 ? 115.883 164.051 106.109 1.00 77.59  ? 335 TYR B O   1 
ATOM   6916  C CB  . TYR B 1 335 ? 113.973 165.851 104.685 1.00 76.01  ? 335 TYR B CB  1 
ATOM   6917  C CG  . TYR B 1 335 ? 114.871 166.987 104.255 1.00 77.75  ? 335 TYR B CG  1 
ATOM   6918  C CD1 . TYR B 1 335 ? 114.705 167.576 102.989 1.00 78.66  ? 335 TYR B CD1 1 
ATOM   6919  C CD2 . TYR B 1 335 ? 115.886 167.444 105.106 1.00 72.59  ? 335 TYR B CD2 1 
ATOM   6920  C CE1 . TYR B 1 335 ? 115.573 168.593 102.568 1.00 76.74  ? 335 TYR B CE1 1 
ATOM   6921  C CE2 . TYR B 1 335 ? 116.750 168.471 104.691 1.00 72.75  ? 335 TYR B CE2 1 
ATOM   6922  C CZ  . TYR B 1 335 ? 116.609 169.033 103.412 1.00 77.48  ? 335 TYR B CZ  1 
ATOM   6923  O OH  . TYR B 1 335 ? 117.482 169.982 102.998 1.00 79.17  ? 335 TYR B OH  1 
ATOM   6924  N N   . GLY B 1 336 ? 116.757 163.703 104.086 1.00 73.00  ? 336 GLY B N   1 
ATOM   6925  C CA  . GLY B 1 336 ? 118.019 163.190 104.581 1.00 74.84  ? 336 GLY B CA  1 
ATOM   6926  C C   . GLY B 1 336 ? 117.793 161.909 105.388 1.00 77.83  ? 336 GLY B C   1 
ATOM   6927  O O   . GLY B 1 336 ? 117.014 161.061 104.957 1.00 79.79  ? 336 GLY B O   1 
ATOM   6928  N N   . PRO B 1 337 ? 118.421 161.743 106.560 1.00 77.11  ? 337 PRO B N   1 
ATOM   6929  C CA  . PRO B 1 337 ? 118.275 160.561 107.395 1.00 77.58  ? 337 PRO B CA  1 
ATOM   6930  C C   . PRO B 1 337 ? 116.924 160.492 108.119 1.00 81.45  ? 337 PRO B C   1 
ATOM   6931  O O   . PRO B 1 337 ? 116.696 159.541 108.864 1.00 80.76  ? 337 PRO B O   1 
ATOM   6932  C CB  . PRO B 1 337 ? 119.447 160.641 108.371 1.00 69.71  ? 337 PRO B CB  1 
ATOM   6933  C CG  . PRO B 1 337 ? 119.616 162.135 108.564 1.00 73.21  ? 337 PRO B CG  1 
ATOM   6934  C CD  . PRO B 1 337 ? 119.320 162.684 107.180 1.00 72.39  ? 337 PRO B CD  1 
ATOM   6935  N N   . VAL B 1 338 ? 116.042 161.479 107.945 1.00 83.39  ? 338 VAL B N   1 
ATOM   6936  C CA  . VAL B 1 338 ? 114.808 161.632 108.718 1.00 80.52  ? 338 VAL B CA  1 
ATOM   6937  C C   . VAL B 1 338 ? 113.600 161.205 107.900 1.00 80.90  ? 338 VAL B C   1 
ATOM   6938  O O   . VAL B 1 338 ? 113.347 161.755 106.831 1.00 82.96  ? 338 VAL B O   1 
ATOM   6939  C CB  . VAL B 1 338 ? 114.622 163.078 109.208 1.00 74.15  ? 338 VAL B CB  1 
ATOM   6940  C CG1 . VAL B 1 338 ? 113.485 163.148 110.230 1.00 74.68  ? 338 VAL B CG1 1 
ATOM   6941  C CG2 . VAL B 1 338 ? 115.911 163.626 109.822 1.00 71.64  ? 338 VAL B CG2 1 
ATOM   6942  N N   . ARG B 1 339 ? 112.814 160.262 108.424 1.00 81.97  ? 339 ARG B N   1 
ATOM   6943  C CA  . ARG B 1 339 ? 111.493 159.897 107.907 1.00 82.30  ? 339 ARG B CA  1 
ATOM   6944  C C   . ARG B 1 339 ? 110.429 160.269 108.921 1.00 81.74  ? 339 ARG B C   1 
ATOM   6945  O O   . ARG B 1 339 ? 110.550 159.905 110.083 1.00 90.00  ? 339 ARG B O   1 
ATOM   6946  C CB  . ARG B 1 339 ? 111.408 158.395 107.620 1.00 84.63  ? 339 ARG B CB  1 
ATOM   6947  C CG  . ARG B 1 339 ? 112.436 157.918 106.590 1.00 88.26  ? 339 ARG B CG  1 
ATOM   6948  C CD  . ARG B 1 339 ? 112.165 156.476 106.157 1.00 86.21  ? 339 ARG B CD  1 
ATOM   6949  N NE  . ARG B 1 339 ? 110.960 156.379 105.307 1.00 90.05  ? 339 ARG B NE  1 
ATOM   6950  C CZ  . ARG B 1 339 ? 110.921 156.302 103.989 1.00 93.03  ? 339 ARG B CZ  1 
ATOM   6951  N NH1 . ARG B 1 339 ? 109.783 156.222 103.366 1.00 91.10  ? 339 ARG B NH1 1 
ATOM   6952  N NH2 . ARG B 1 339 ? 111.995 156.302 103.256 1.00 93.48  ? 339 ARG B NH2 1 
ATOM   6953  N N   . VAL B 1 340 ? 109.359 160.922 108.493 1.00 68.47  ? 340 VAL B N   1 
ATOM   6954  C CA  . VAL B 1 340 ? 108.159 161.122 109.310 1.00 66.56  ? 340 VAL B CA  1 
ATOM   6955  C C   . VAL B 1 340 ? 107.034 160.267 108.751 1.00 75.70  ? 340 VAL B C   1 
ATOM   6956  O O   . VAL B 1 340 ? 106.726 160.353 107.568 1.00 85.22  ? 340 VAL B O   1 
ATOM   6957  C CB  . VAL B 1 340 ? 107.794 162.605 109.393 1.00 64.03  ? 340 VAL B CB  1 
ATOM   6958  C CG1 . VAL B 1 340 ? 106.535 162.820 110.229 1.00 70.34  ? 340 VAL B CG1 1 
ATOM   6959  C CG2 . VAL B 1 340 ? 108.953 163.356 110.045 1.00 73.70  ? 340 VAL B CG2 1 
ATOM   6960  N N   . SER B 1 341 ? 106.423 159.423 109.580 1.00 70.89  ? 341 SER B N   1 
ATOM   6961  C CA  . SER B 1 341 ? 105.396 158.464 109.170 1.00 65.48  ? 341 SER B CA  1 
ATOM   6962  C C   . SER B 1 341 ? 104.178 158.535 110.071 1.00 67.10  ? 341 SER B C   1 
ATOM   6963  O O   . SER B 1 341 ? 104.309 158.592 111.286 1.00 82.65  ? 341 SER B O   1 
ATOM   6964  C CB  . SER B 1 341 ? 105.925 157.034 109.206 1.00 68.13  ? 341 SER B CB  1 
ATOM   6965  O OG  . SER B 1 341 ? 107.079 156.883 108.411 1.00 78.86  ? 341 SER B OG  1 
ATOM   6966  N N   . LEU B 1 342 ? 102.989 158.464 109.491 1.00 61.67  ? 342 LEU B N   1 
ATOM   6967  C CA  . LEU B 1 342 ? 101.739 158.224 110.198 1.00 58.61  ? 342 LEU B CA  1 
ATOM   6968  C C   . LEU B 1 342 ? 101.501 156.720 110.306 1.00 59.97  ? 342 LEU B C   1 
ATOM   6969  O O   . LEU B 1 342 ? 101.473 156.038 109.292 1.00 71.36  ? 342 LEU B O   1 
ATOM   6970  C CB  . LEU B 1 342 ? 100.599 158.873 109.403 1.00 64.04  ? 342 LEU B CB  1 
ATOM   6971  C CG  . LEU B 1 342 ? 100.657 160.398 109.297 1.00 60.17  ? 342 LEU B CG  1 
ATOM   6972  C CD1 . LEU B 1 342 ? 99.488  160.878 108.448 1.00 68.02  ? 342 LEU B CD1 1 
ATOM   6973  C CD2 . LEU B 1 342 ? 100.569 161.068 110.661 1.00 60.14  ? 342 LEU B CD2 1 
ATOM   6974  N N   . TYR B 1 343 ? 101.309 156.193 111.507 1.00 57.47  ? 343 TYR B N   1 
ATOM   6975  C CA  . TYR B 1 343 ? 100.938 154.802 111.749 1.00 58.15  ? 343 TYR B CA  1 
ATOM   6976  C C   . TYR B 1 343 ? 99.480  154.696 112.199 1.00 67.60  ? 343 TYR B C   1 
ATOM   6977  O O   . TYR B 1 343 ? 99.040  155.434 113.069 1.00 75.03  ? 343 TYR B O   1 
ATOM   6978  C CB  . TYR B 1 343 ? 101.863 154.203 112.797 1.00 56.61  ? 343 TYR B CB  1 
ATOM   6979  C CG  . TYR B 1 343 ? 103.272 153.906 112.332 1.00 52.20  ? 343 TYR B CG  1 
ATOM   6980  C CD1 . TYR B 1 343 ? 104.272 154.887 112.421 1.00 55.58  ? 343 TYR B CD1 1 
ATOM   6981  C CD2 . TYR B 1 343 ? 103.597 152.615 111.893 1.00 56.32  ? 343 TYR B CD2 1 
ATOM   6982  C CE1 . TYR B 1 343 ? 105.603 154.558 112.107 1.00 61.52  ? 343 TYR B CE1 1 
ATOM   6983  C CE2 . TYR B 1 343 ? 104.929 152.283 111.604 1.00 59.31  ? 343 TYR B CE2 1 
ATOM   6984  C CZ  . TYR B 1 343 ? 105.940 153.250 111.736 1.00 61.95  ? 343 TYR B CZ  1 
ATOM   6985  O OH  . TYR B 1 343 ? 107.237 152.934 111.500 1.00 62.91  ? 343 TYR B OH  1 
ATOM   6986  N N   . ASP B 1 344 ? 98.721  153.776 111.623 1.00 71.01  ? 344 ASP B N   1 
ATOM   6987  C CA  . ASP B 1 344 ? 97.315  153.505 111.912 1.00 69.50  ? 344 ASP B CA  1 
ATOM   6988  C C   . ASP B 1 344 ? 97.128  152.722 113.227 1.00 72.06  ? 344 ASP B C   1 
ATOM   6989  O O   . ASP B 1 344 ? 97.583  151.584 113.346 1.00 78.52  ? 344 ASP B O   1 
ATOM   6990  C CB  . ASP B 1 344 ? 96.781  152.731 110.705 1.00 72.25  ? 344 ASP B CB  1 
ATOM   6991  C CG  . ASP B 1 344 ? 95.317  152.325 110.790 1.00 71.87  ? 344 ASP B CG  1 
ATOM   6992  O OD1 . ASP B 1 344 ? 94.637  152.702 111.766 1.00 76.52  ? 344 ASP B OD1 1 
ATOM   6993  O OD2 . ASP B 1 344 ? 94.862  151.651 109.843 1.00 63.91  ? 344 ASP B OD2 1 
ATOM   6994  N N   . LEU B 1 345 ? 96.446  153.310 114.216 1.00 66.69  ? 345 LEU B N   1 
ATOM   6995  C CA  . LEU B 1 345 ? 96.282  152.743 115.555 1.00 60.02  ? 345 LEU B CA  1 
ATOM   6996  C C   . LEU B 1 345 ? 94.982  151.949 115.782 1.00 60.34  ? 345 LEU B C   1 
ATOM   6997  O O   . LEU B 1 345 ? 94.671  151.638 116.929 1.00 70.84  ? 345 LEU B O   1 
ATOM   6998  C CB  . LEU B 1 345 ? 96.435  153.846 116.616 1.00 61.42  ? 345 LEU B CB  1 
ATOM   6999  C CG  . LEU B 1 345 ? 97.786  154.562 116.691 1.00 57.89  ? 345 LEU B CG  1 
ATOM   7000  C CD1 . LEU B 1 345 ? 97.830  155.322 118.011 1.00 68.00  ? 345 LEU B CD1 1 
ATOM   7001  C CD2 . LEU B 1 345 ? 98.972  153.606 116.667 1.00 65.68  ? 345 LEU B CD2 1 
ATOM   7002  N N   . SER B 1 346 ? 94.222  151.596 114.743 1.00 65.68  ? 346 SER B N   1 
ATOM   7003  C CA  . SER B 1 346 ? 92.847  151.070 114.858 1.00 73.41  ? 346 SER B CA  1 
ATOM   7004  C C   . SER B 1 346 ? 92.635  149.958 115.903 1.00 79.54  ? 346 SER B C   1 
ATOM   7005  O O   . SER B 1 346 ? 91.876  150.147 116.852 1.00 84.43  ? 346 SER B O   1 
ATOM   7006  C CB  . SER B 1 346 ? 92.335  150.624 113.487 1.00 73.10  ? 346 SER B CB  1 
ATOM   7007  O OG  . SER B 1 346 ? 93.111  149.567 112.942 1.00 71.95  ? 346 SER B OG  1 
ATOM   7008  N N   . SER B 1 347 ? 93.321  148.821 115.780 1.00 67.78  ? 347 SER B N   1 
ATOM   7009  C CA  . SER B 1 347 ? 93.315  147.720 116.748 1.00 60.97  ? 347 SER B CA  1 
ATOM   7010  C C   . SER B 1 347 ? 94.312  147.884 117.898 1.00 67.38  ? 347 SER B C   1 
ATOM   7011  O O   . SER B 1 347 ? 94.424  146.983 118.726 1.00 77.64  ? 347 SER B O   1 
ATOM   7012  C CB  . SER B 1 347 ? 93.645  146.410 116.023 1.00 67.47  ? 347 SER B CB  1 
ATOM   7013  O OG  . SER B 1 347 ? 92.839  146.216 114.877 1.00 70.30  ? 347 SER B OG  1 
ATOM   7014  N N   . VAL B 1 348 ? 95.108  148.955 117.916 1.00 67.71  ? 348 VAL B N   1 
ATOM   7015  C CA  . VAL B 1 348 ? 96.358  149.056 118.684 1.00 61.35  ? 348 VAL B CA  1 
ATOM   7016  C C   . VAL B 1 348 ? 96.232  149.860 119.974 1.00 59.48  ? 348 VAL B C   1 
ATOM   7017  O O   . VAL B 1 348 ? 96.751  149.428 120.996 1.00 63.30  ? 348 VAL B O   1 
ATOM   7018  C CB  . VAL B 1 348 ? 97.504  149.581 117.801 1.00 61.56  ? 348 VAL B CB  1 
ATOM   7019  C CG1 . VAL B 1 348 ? 98.828  149.699 118.551 1.00 59.46  ? 348 VAL B CG1 1 
ATOM   7020  C CG2 . VAL B 1 348 ? 97.763  148.666 116.601 1.00 61.42  ? 348 VAL B CG2 1 
ATOM   7021  N N   . ASP B 1 349 ? 95.579  151.017 119.916 1.00 74.71  ? 349 ASP B N   1 
ATOM   7022  C CA  . ASP B 1 349 ? 95.456  151.903 121.066 1.00 77.73  ? 349 ASP B CA  1 
ATOM   7023  C C   . ASP B 1 349 ? 94.558  151.275 122.141 1.00 88.05  ? 349 ASP B C   1 
ATOM   7024  O O   . ASP B 1 349 ? 93.472  150.767 121.863 1.00 88.56  ? 349 ASP B O   1 
ATOM   7025  C CB  . ASP B 1 349 ? 94.951  153.279 120.614 1.00 73.42  ? 349 ASP B CB  1 
ATOM   7026  C CG  . ASP B 1 349 ? 94.917  154.322 121.740 1.00 86.49  ? 349 ASP B CG  1 
ATOM   7027  O OD1 . ASP B 1 349 ? 95.593  154.114 122.777 1.00 86.69  ? 349 ASP B OD1 1 
ATOM   7028  O OD2 . ASP B 1 349 ? 94.200  155.328 121.568 1.00 90.94  ? 349 ASP B OD2 1 
ATOM   7029  N N   . SER B 1 350 ? 95.000  151.352 123.391 1.00 85.64  ? 350 SER B N   1 
ATOM   7030  C CA  . SER B 1 350 ? 94.368  150.791 124.582 1.00 78.85  ? 350 SER B CA  1 
ATOM   7031  C C   . SER B 1 350 ? 93.038  151.442 124.970 1.00 74.93  ? 350 SER B C   1 
ATOM   7032  O O   . SER B 1 350 ? 92.370  150.980 125.896 1.00 78.80  ? 350 SER B O   1 
ATOM   7033  C CB  . SER B 1 350 ? 95.379  150.870 125.717 1.00 82.47  ? 350 SER B CB  1 
ATOM   7034  O OG  . SER B 1 350 ? 95.869  152.183 125.829 1.00 86.56  ? 350 SER B OG  1 
ATOM   7035  N N   . TRP B 1 351 ? 92.621  152.483 124.255 1.00 82.44  ? 351 TRP B N   1 
ATOM   7036  C CA  . TRP B 1 351 ? 91.265  153.024 124.266 1.00 85.36  ? 351 TRP B CA  1 
ATOM   7037  C C   . TRP B 1 351 ? 90.213  151.974 123.874 1.00 89.91  ? 351 TRP B C   1 
ATOM   7038  O O   . TRP B 1 351 ? 89.127  151.938 124.447 1.00 91.59  ? 351 TRP B O   1 
ATOM   7039  C CB  . TRP B 1 351 ? 91.257  154.224 123.312 1.00 84.69  ? 351 TRP B CB  1 
ATOM   7040  C CG  . TRP B 1 351 ? 89.940  154.881 123.071 1.00 89.69  ? 351 TRP B CG  1 
ATOM   7041  C CD1 . TRP B 1 351 ? 89.448  155.923 123.775 1.00 91.81  ? 351 TRP B CD1 1 
ATOM   7042  C CD2 . TRP B 1 351 ? 88.931  154.561 122.068 1.00 93.15  ? 351 TRP B CD2 1 
ATOM   7043  N NE1 . TRP B 1 351 ? 88.207  156.267 123.286 1.00 89.85  ? 351 TRP B NE1 1 
ATOM   7044  C CE2 . TRP B 1 351 ? 87.836  155.462 122.231 1.00 90.81  ? 351 TRP B CE2 1 
ATOM   7045  C CE3 . TRP B 1 351 ? 88.830  153.616 121.026 1.00 92.06  ? 351 TRP B CE3 1 
ATOM   7046  C CZ2 . TRP B 1 351 ? 86.698  155.416 121.418 1.00 86.56  ? 351 TRP B CZ2 1 
ATOM   7047  C CZ3 . TRP B 1 351 ? 87.686  153.556 120.207 1.00 90.74  ? 351 TRP B CZ3 1 
ATOM   7048  C CH2 . TRP B 1 351 ? 86.622  154.450 120.403 1.00 87.77  ? 351 TRP B CH2 1 
ATOM   7049  N N   . GLU B 1 352 ? 90.543  151.076 122.944 1.00 95.32  ? 352 GLU B N   1 
ATOM   7050  C CA  . GLU B 1 352 ? 89.717  149.918 122.588 1.00 95.96  ? 352 GLU B CA  1 
ATOM   7051  C C   . GLU B 1 352 ? 89.912  148.751 123.576 1.00 97.84  ? 352 GLU B C   1 
ATOM   7052  O O   . GLU B 1 352 ? 91.042  148.378 123.911 1.00 99.88  ? 352 GLU B O   1 
ATOM   7053  C CB  . GLU B 1 352 ? 90.014  149.518 121.129 1.00 91.70  ? 352 GLU B CB  1 
ATOM   7054  N N   . LYS B 1 353 ? 88.813  148.123 124.007 1.00 89.28  ? 353 LYS B N   1 
ATOM   7055  C CA  . LYS B 1 353 ? 88.830  146.883 124.800 1.00 89.62  ? 353 LYS B CA  1 
ATOM   7056  C C   . LYS B 1 353 ? 89.337  145.713 123.960 1.00 93.23  ? 353 LYS B C   1 
ATOM   7057  O O   . LYS B 1 353 ? 88.952  145.596 122.799 1.00 91.67  ? 353 LYS B O   1 
ATOM   7058  C CB  . LYS B 1 353 ? 87.420  146.585 125.336 1.00 91.53  ? 353 LYS B CB  1 
ATOM   7059  C CG  . LYS B 1 353 ? 86.908  147.655 126.309 1.00 94.52  ? 353 LYS B CG  1 
ATOM   7060  C CD  . LYS B 1 353 ? 85.490  147.325 126.783 1.00 95.05  ? 353 LYS B CD  1 
ATOM   7061  C CE  . LYS B 1 353 ? 84.975  148.424 127.712 1.00 93.52  ? 353 LYS B CE  1 
ATOM   7062  N NZ  . LYS B 1 353 ? 83.587  148.164 128.153 1.00 95.07  ? 353 LYS B NZ  1 
ATOM   7063  N N   . ASN B 1 354 ? 90.157  144.823 124.523 1.00 81.99  ? 354 ASN B N   1 
ATOM   7064  C CA  . ASN B 1 354 ? 90.795  143.725 123.781 1.00 78.89  ? 354 ASN B CA  1 
ATOM   7065  C C   . ASN B 1 354 ? 91.652  144.222 122.599 1.00 79.07  ? 354 ASN B C   1 
ATOM   7066  O O   . ASN B 1 354 ? 91.564  143.722 121.480 1.00 85.90  ? 354 ASN B O   1 
ATOM   7067  C CB  . ASN B 1 354 ? 89.740  142.661 123.420 1.00 86.04  ? 354 ASN B CB  1 
ATOM   7068  C CG  . ASN B 1 354 ? 90.344  141.372 122.900 1.00 90.81  ? 354 ASN B CG  1 
ATOM   7069  O OD1 . ASN B 1 354 ? 91.366  140.908 123.377 1.00 88.85  ? 354 ASN B OD1 1 
ATOM   7070  N ND2 . ASN B 1 354 ? 89.722  140.742 121.935 1.00 84.37  ? 354 ASN B ND2 1 
ATOM   7071  N N   . SER B 1 355 ? 92.428  145.284 122.801 1.00 69.85  ? 355 SER B N   1 
ATOM   7072  C CA  . SER B 1 355 ? 93.387  145.833 121.836 1.00 59.36  ? 355 SER B CA  1 
ATOM   7073  C C   . SER B 1 355 ? 94.740  145.122 121.889 1.00 62.73  ? 355 SER B C   1 
ATOM   7074  O O   . SER B 1 355 ? 95.038  144.381 122.817 1.00 78.13  ? 355 SER B O   1 
ATOM   7075  C CB  . SER B 1 355 ? 93.564  147.329 122.088 1.00 59.88  ? 355 SER B CB  1 
ATOM   7076  O OG  . SER B 1 355 ? 93.710  147.587 123.465 1.00 60.43  ? 355 SER B OG  1 
ATOM   7077  N N   . VAL B 1 356 ? 95.586  145.351 120.890 1.00 46.41  ? 356 VAL B N   1 
ATOM   7078  C CA  . VAL B 1 356 ? 96.919  144.730 120.747 1.00 39.39  ? 356 VAL B CA  1 
ATOM   7079  C C   . VAL B 1 356 ? 97.827  144.984 121.950 1.00 46.49  ? 356 VAL B C   1 
ATOM   7080  O O   . VAL B 1 356 ? 98.584  144.104 122.334 1.00 70.73  ? 356 VAL B O   1 
ATOM   7081  C CB  . VAL B 1 356 ? 97.589  145.214 119.451 1.00 49.47  ? 356 VAL B CB  1 
ATOM   7082  C CG1 . VAL B 1 356 ? 99.078  144.927 119.320 1.00 52.94  ? 356 VAL B CG1 1 
ATOM   7083  C CG2 . VAL B 1 356 ? 96.904  144.601 118.231 1.00 52.81  ? 356 VAL B CG2 1 
ATOM   7084  N N   . LEU B 1 357 ? 97.771  146.167 122.556 1.00 60.77  ? 357 LEU B N   1 
ATOM   7085  C CA  . LEU B 1 357 ? 98.561  146.465 123.747 1.00 56.43  ? 357 LEU B CA  1 
ATOM   7086  C C   . LEU B 1 357 ? 98.100  145.645 124.959 1.00 62.16  ? 357 LEU B C   1 
ATOM   7087  O O   . LEU B 1 357 ? 98.926  145.063 125.653 1.00 67.67  ? 357 LEU B O   1 
ATOM   7088  C CB  . LEU B 1 357 ? 98.499  147.974 124.021 1.00 57.65  ? 357 LEU B CB  1 
ATOM   7089  C CG  . LEU B 1 357 ? 99.289  148.838 123.030 1.00 64.38  ? 357 LEU B CG  1 
ATOM   7090  C CD1 . LEU B 1 357 ? 99.086  150.304 123.393 1.00 67.91  ? 357 LEU B CD1 1 
ATOM   7091  C CD2 . LEU B 1 357 ? 100.779 148.520 123.087 1.00 61.92  ? 357 LEU B CD2 1 
ATOM   7092  N N   . GLU B 1 358 ? 96.790  145.531 125.189 1.00 74.43  ? 358 GLU B N   1 
ATOM   7093  C CA  . GLU B 1 358 ? 96.224  144.670 126.229 1.00 66.70  ? 358 GLU B CA  1 
ATOM   7094  C C   . GLU B 1 358 ? 96.589  143.196 126.017 1.00 67.83  ? 358 GLU B C   1 
ATOM   7095  O O   . GLU B 1 358 ? 96.986  142.506 126.948 1.00 83.17  ? 358 GLU B O   1 
ATOM   7096  C CB  . GLU B 1 358 ? 94.704  144.887 126.286 1.00 69.92  ? 358 GLU B CB  1 
ATOM   7097  C CG  . GLU B 1 358 ? 93.986  143.895 127.205 1.00 82.75  ? 358 GLU B CG  1 
ATOM   7098  C CD  . GLU B 1 358 ? 92.654  144.431 127.740 1.00 86.70  ? 358 GLU B CD  1 
ATOM   7099  O OE1 . GLU B 1 358 ? 91.789  144.832 126.933 1.00 86.01  ? 358 GLU B OE1 1 
ATOM   7100  O OE2 . GLU B 1 358 ? 92.480  144.434 128.980 1.00 85.48  ? 358 GLU B OE2 1 
ATOM   7101  N N   . ILE B 1 359 ? 96.535  142.721 124.781 1.00 59.62  ? 359 ILE B N   1 
ATOM   7102  C CA  . ILE B 1 359 ? 96.907  141.366 124.369 1.00 55.03  ? 359 ILE B CA  1 
ATOM   7103  C C   . ILE B 1 359 ? 98.374  141.050 124.659 1.00 61.96  ? 359 ILE B C   1 
ATOM   7104  O O   . ILE B 1 359 ? 98.646  140.032 125.286 1.00 84.17  ? 359 ILE B O   1 
ATOM   7105  C CB  . ILE B 1 359 ? 96.549  141.122 122.890 1.00 49.39  ? 359 ILE B CB  1 
ATOM   7106  C CG1 . ILE B 1 359 ? 95.022  141.012 122.740 1.00 56.90  ? 359 ILE B CG1 1 
ATOM   7107  C CG2 . ILE B 1 359 ? 97.206  139.847 122.352 1.00 58.96  ? 359 ILE B CG2 1 
ATOM   7108  C CD1 . ILE B 1 359 ? 94.538  141.071 121.298 1.00 56.10  ? 359 ILE B CD1 1 
ATOM   7109  N N   . ILE B 1 360 ? 99.332  141.883 124.255 1.00 57.87  ? 360 ILE B N   1 
ATOM   7110  C CA  . ILE B 1 360 ? 100.758 141.627 124.512 1.00 52.91  ? 360 ILE B CA  1 
ATOM   7111  C C   . ILE B 1 360 ? 101.036 141.603 126.014 1.00 65.30  ? 360 ILE B C   1 
ATOM   7112  O O   . ILE B 1 360 ? 101.768 140.740 126.498 1.00 77.56  ? 360 ILE B O   1 
ATOM   7113  C CB  . ILE B 1 360 ? 101.650 142.671 123.814 1.00 59.37  ? 360 ILE B CB  1 
ATOM   7114  C CG1 . ILE B 1 360 ? 101.531 142.549 122.288 1.00 58.80  ? 360 ILE B CG1 1 
ATOM   7115  C CG2 . ILE B 1 360 ? 103.119 142.518 124.234 1.00 59.81  ? 360 ILE B CG2 1 
ATOM   7116  C CD1 . ILE B 1 360 ? 101.998 143.804 121.561 1.00 57.86  ? 360 ILE B CD1 1 
ATOM   7117  N N   . ALA B 1 361 ? 100.456 142.540 126.753 1.00 64.11  ? 361 ALA B N   1 
ATOM   7118  C CA  . ALA B 1 361 ? 100.654 142.619 128.180 1.00 63.38  ? 361 ALA B CA  1 
ATOM   7119  C C   . ALA B 1 361 ? 100.025 141.413 128.901 1.00 64.22  ? 361 ALA B C   1 
ATOM   7120  O O   . ALA B 1 361 ? 100.710 140.755 129.674 1.00 67.29  ? 361 ALA B O   1 
ATOM   7121  C CB  . ALA B 1 361 ? 100.111 143.964 128.647 1.00 68.50  ? 361 ALA B CB  1 
ATOM   7122  N N   . PHE B 1 362 ? 98.759  141.090 128.625 1.00 72.86  ? 362 PHE B N   1 
ATOM   7123  C CA  . PHE B 1 362 ? 97.951  140.237 129.500 1.00 76.37  ? 362 PHE B CA  1 
ATOM   7124  C C   . PHE B 1 362 ? 97.428  138.931 128.889 1.00 76.15  ? 362 PHE B C   1 
ATOM   7125  O O   . PHE B 1 362 ? 97.050  138.044 129.648 1.00 85.79  ? 362 PHE B O   1 
ATOM   7126  C CB  . PHE B 1 362 ? 96.784  141.071 130.045 1.00 72.17  ? 362 PHE B CB  1 
ATOM   7127  C CG  . PHE B 1 362 ? 97.210  142.340 130.755 1.00 74.14  ? 362 PHE B CG  1 
ATOM   7128  C CD1 . PHE B 1 362 ? 97.869  142.269 131.992 1.00 79.87  ? 362 PHE B CD1 1 
ATOM   7129  C CD2 . PHE B 1 362 ? 96.974  143.591 130.170 1.00 74.99  ? 362 PHE B CD2 1 
ATOM   7130  C CE1 . PHE B 1 362 ? 98.307  143.443 132.625 1.00 75.55  ? 362 PHE B CE1 1 
ATOM   7131  C CE2 . PHE B 1 362 ? 97.419  144.765 130.799 1.00 76.61  ? 362 PHE B CE2 1 
ATOM   7132  C CZ  . PHE B 1 362 ? 98.095  144.689 132.020 1.00 75.45  ? 362 PHE B CZ  1 
ATOM   7133  N N   . HIS B 1 363 ? 97.364  138.773 127.565 1.00 68.85  ? 363 HIS B N   1 
ATOM   7134  C CA  . HIS B 1 363 ? 96.806  137.567 126.929 1.00 73.14  ? 363 HIS B CA  1 
ATOM   7135  C C   . HIS B 1 363 ? 97.845  136.705 126.205 1.00 76.67  ? 363 HIS B C   1 
ATOM   7136  O O   . HIS B 1 363 ? 97.600  135.528 125.961 1.00 77.65  ? 363 HIS B O   1 
ATOM   7137  C CB  . HIS B 1 363 ? 95.692  137.935 125.947 1.00 69.08  ? 363 HIS B CB  1 
ATOM   7138  C CG  . HIS B 1 363 ? 94.567  138.785 126.473 1.00 70.97  ? 363 HIS B CG  1 
ATOM   7139  N ND1 . HIS B 1 363 ? 93.615  139.387 125.657 1.00 83.77  ? 363 HIS B ND1 1 
ATOM   7140  C CD2 . HIS B 1 363 ? 94.256  139.055 127.770 1.00 78.05  ? 363 HIS B CD2 1 
ATOM   7141  C CE1 . HIS B 1 363 ? 92.776  140.038 126.475 1.00 79.97  ? 363 HIS B CE1 1 
ATOM   7142  N NE2 . HIS B 1 363 ? 93.138  139.855 127.752 1.00 80.44  ? 363 HIS B NE2 1 
ATOM   7143  N N   . CYS B 1 364 ? 98.991  137.268 125.848 1.00 70.95  ? 364 CYS B N   1 
ATOM   7144  C CA  . CYS B 1 364 ? 100.099 136.573 125.213 1.00 73.86  ? 364 CYS B CA  1 
ATOM   7145  C C   . CYS B 1 364 ? 100.882 135.715 126.225 1.00 80.60  ? 364 CYS B C   1 
ATOM   7146  O O   . CYS B 1 364 ? 101.275 136.222 127.267 1.00 78.85  ? 364 CYS B O   1 
ATOM   7147  C CB  . CYS B 1 364 ? 100.970 137.653 124.568 1.00 67.86  ? 364 CYS B CB  1 
ATOM   7148  S SG  . CYS B 1 364 ? 102.295 136.923 123.587 1.00 80.65  ? 364 CYS B SG  1 
ATOM   7149  N N   . LYS B 1 365 ? 101.153 134.432 125.936 1.00 90.59  ? 365 LYS B N   1 
ATOM   7150  C CA  . LYS B 1 365 ? 101.947 133.526 126.801 1.00 86.95  ? 365 LYS B CA  1 
ATOM   7151  C C   . LYS B 1 365 ? 103.459 133.541 126.542 1.00 88.71  ? 365 LYS B C   1 
ATOM   7152  O O   . LYS B 1 365 ? 104.224 132.974 127.317 1.00 95.80  ? 365 LYS B O   1 
ATOM   7153  C CB  . LYS B 1 365 ? 101.457 132.077 126.631 1.00 92.54  ? 365 LYS B CB  1 
ATOM   7154  C CG  . LYS B 1 365 ? 100.058 131.837 127.193 1.00 96.30  ? 365 LYS B CG  1 
ATOM   7155  C CD  . LYS B 1 365 ? 99.684  130.357 127.131 1.00 96.76  ? 365 LYS B CD  1 
ATOM   7156  C CE  . LYS B 1 365 ? 98.308  130.134 127.746 1.00 94.99  ? 365 LYS B CE  1 
ATOM   7157  N NZ  . LYS B 1 365 ? 97.926  128.713 127.748 1.00 94.43  ? 365 LYS B NZ  1 
ATOM   7158  N N   . SER B 1 366 ? 103.893 134.081 125.409 1.00 78.55  ? 366 SER B N   1 
ATOM   7159  C CA  . SER B 1 366 ? 105.195 133.763 124.798 1.00 80.43  ? 366 SER B CA  1 
ATOM   7160  C C   . SER B 1 366 ? 106.400 134.482 125.425 1.00 79.96  ? 366 SER B C   1 
ATOM   7161  O O   . SER B 1 366 ? 106.255 135.573 125.975 1.00 79.27  ? 366 SER B O   1 
ATOM   7162  C CB  . SER B 1 366 ? 105.141 134.063 123.302 1.00 77.02  ? 366 SER B CB  1 
ATOM   7163  O OG  . SER B 1 366 ? 105.134 135.457 123.084 1.00 78.57  ? 366 SER B OG  1 
ATOM   7164  N N   . PRO B 1 367 ? 107.629 133.948 125.266 1.00 83.72  ? 367 PRO B N   1 
ATOM   7165  C CA  . PRO B 1 367 ? 108.865 134.668 125.580 1.00 79.89  ? 367 PRO B CA  1 
ATOM   7166  C C   . PRO B 1 367 ? 109.030 135.988 124.819 1.00 77.43  ? 367 PRO B C   1 
ATOM   7167  O O   . PRO B 1 367 ? 109.780 136.861 125.237 1.00 77.18  ? 367 PRO B O   1 
ATOM   7168  C CB  . PRO B 1 367 ? 110.000 133.716 125.191 1.00 79.48  ? 367 PRO B CB  1 
ATOM   7169  C CG  . PRO B 1 367 ? 109.364 132.338 125.255 1.00 79.05  ? 367 PRO B CG  1 
ATOM   7170  C CD  . PRO B 1 367 ? 107.931 132.600 124.822 1.00 79.60  ? 367 PRO B CD  1 
ATOM   7171  N N   . ASN B 1 368 ? 108.364 136.131 123.671 1.00 90.09  ? 368 ASN B N   1 
ATOM   7172  C CA  . ASN B 1 368 ? 108.531 137.219 122.704 1.00 84.24  ? 368 ASN B CA  1 
ATOM   7173  C C   . ASN B 1 368 ? 107.901 138.560 123.110 1.00 78.84  ? 368 ASN B C   1 
ATOM   7174  O O   . ASN B 1 368 ? 108.132 139.556 122.434 1.00 85.32  ? 368 ASN B O   1 
ATOM   7175  C CB  . ASN B 1 368 ? 107.943 136.753 121.359 1.00 82.28  ? 368 ASN B CB  1 
ATOM   7176  C CG  . ASN B 1 368 ? 108.813 135.752 120.622 1.00 82.34  ? 368 ASN B CG  1 
ATOM   7177  O OD1 . ASN B 1 368 ? 110.011 135.645 120.820 1.00 84.85  ? 368 ASN B OD1 1 
ATOM   7178  N ND2 . ASN B 1 368 ? 108.241 134.981 119.739 1.00 81.44  ? 368 ASN B ND2 1 
ATOM   7179  N N   . ARG B 1 369 ? 107.104 138.638 124.179 1.00 69.69  ? 369 ARG B N   1 
ATOM   7180  C CA  . ARG B 1 369 ? 106.340 139.849 124.538 1.00 69.13  ? 369 ARG B CA  1 
ATOM   7181  C C   . ARG B 1 369 ? 107.202 141.086 124.687 1.00 71.92  ? 369 ARG B C   1 
ATOM   7182  O O   . ARG B 1 369 ? 106.826 142.156 124.226 1.00 67.72  ? 369 ARG B O   1 
ATOM   7183  C CB  . ARG B 1 369 ? 105.595 139.600 125.847 1.00 71.99  ? 369 ARG B CB  1 
ATOM   7184  C CG  . ARG B 1 369 ? 104.432 138.647 125.626 1.00 70.51  ? 369 ARG B CG  1 
ATOM   7185  C CD  . ARG B 1 369 ? 104.019 137.990 126.930 1.00 76.54  ? 369 ARG B CD  1 
ATOM   7186  N NE  . ARG B 1 369 ? 103.508 138.952 127.914 1.00 70.13  ? 369 ARG B NE  1 
ATOM   7187  C CZ  . ARG B 1 369 ? 103.991 139.146 129.123 1.00 69.22  ? 369 ARG B CZ  1 
ATOM   7188  N NH1 . ARG B 1 369 ? 103.405 139.917 129.978 1.00 76.06  ? 369 ARG B NH1 1 
ATOM   7189  N NH2 . ARG B 1 369 ? 105.086 138.591 129.539 1.00 69.68  ? 369 ARG B NH2 1 
ATOM   7190  N N   . HIS B 1 370 ? 108.374 140.950 125.295 1.00 78.64  ? 370 HIS B N   1 
ATOM   7191  C CA  . HIS B 1 370 ? 109.271 142.076 125.497 1.00 75.64  ? 370 HIS B CA  1 
ATOM   7192  C C   . HIS B 1 370 ? 109.868 142.612 124.189 1.00 74.83  ? 370 HIS B C   1 
ATOM   7193  O O   . HIS B 1 370 ? 110.140 143.801 124.091 1.00 77.47  ? 370 HIS B O   1 
ATOM   7194  C CB  . HIS B 1 370 ? 110.330 141.689 126.530 1.00 75.32  ? 370 HIS B CB  1 
ATOM   7195  C CG  . HIS B 1 370 ? 111.356 140.682 126.086 1.00 73.61  ? 370 HIS B CG  1 
ATOM   7196  N ND1 . HIS B 1 370 ? 112.503 140.955 125.388 1.00 70.71  ? 370 HIS B ND1 1 
ATOM   7197  C CD2 . HIS B 1 370 ? 111.350 139.343 126.348 1.00 76.62  ? 370 HIS B CD2 1 
ATOM   7198  C CE1 . HIS B 1 370 ? 113.181 139.812 125.236 1.00 75.52  ? 370 HIS B CE1 1 
ATOM   7199  N NE2 . HIS B 1 370 ? 112.514 138.795 125.801 1.00 80.09  ? 370 HIS B NE2 1 
ATOM   7200  N N   . ARG B 1 371 ? 109.995 141.780 123.147 1.00 80.75  ? 371 ARG B N   1 
ATOM   7201  C CA  . ARG B 1 371 ? 110.421 142.194 121.799 1.00 76.94  ? 371 ARG B CA  1 
ATOM   7202  C C   . ARG B 1 371 ? 109.309 142.888 121.019 1.00 73.77  ? 371 ARG B C   1 
ATOM   7203  O O   . ARG B 1 371 ? 109.596 143.703 120.158 1.00 75.01  ? 371 ARG B O   1 
ATOM   7204  C CB  . ARG B 1 371 ? 110.922 140.990 120.994 1.00 76.30  ? 371 ARG B CB  1 
ATOM   7205  C CG  . ARG B 1 371 ? 112.242 140.409 121.514 1.00 75.76  ? 371 ARG B CG  1 
ATOM   7206  C CD  . ARG B 1 371 ? 112.754 139.253 120.650 1.00 77.90  ? 371 ARG B CD  1 
ATOM   7207  N NE  . ARG B 1 371 ? 113.061 139.686 119.272 1.00 86.24  ? 371 ARG B NE  1 
ATOM   7208  C CZ  . ARG B 1 371 ? 113.135 138.928 118.192 1.00 85.33  ? 371 ARG B CZ  1 
ATOM   7209  N NH1 . ARG B 1 371 ? 113.308 139.467 117.026 1.00 79.36  ? 371 ARG B NH1 1 
ATOM   7210  N NH2 . ARG B 1 371 ? 113.032 137.633 118.242 1.00 83.05  ? 371 ARG B NH2 1 
ATOM   7211  N N   . MET B 1 372 ? 108.044 142.595 121.319 1.00 67.83  ? 372 MET B N   1 
ATOM   7212  C CA  . MET B 1 372 ? 106.887 143.218 120.667 1.00 58.64  ? 372 MET B CA  1 
ATOM   7213  C C   . MET B 1 372 ? 106.586 144.638 121.154 1.00 70.24  ? 372 MET B C   1 
ATOM   7214  O O   . MET B 1 372 ? 106.216 145.480 120.346 1.00 77.58  ? 372 MET B O   1 
ATOM   7215  C CB  . MET B 1 372 ? 105.647 142.330 120.818 1.00 65.77  ? 372 MET B CB  1 
ATOM   7216  C CG  . MET B 1 372 ? 105.829 141.006 120.076 1.00 71.31  ? 372 MET B CG  1 
ATOM   7217  S SD  . MET B 1 372 ? 104.325 140.034 119.876 1.00 70.26  ? 372 MET B SD  1 
ATOM   7218  C CE  . MET B 1 372 ? 104.102 139.435 121.555 1.00 73.42  ? 372 MET B CE  1 
ATOM   7219  N N   . VAL B 1 373 ? 106.776 144.968 122.427 1.00 74.15  ? 373 VAL B N   1 
ATOM   7220  C CA  . VAL B 1 373 ? 106.503 146.335 122.910 1.00 69.04  ? 373 VAL B CA  1 
ATOM   7221  C C   . VAL B 1 373 ? 107.538 147.368 122.467 1.00 68.68  ? 373 VAL B C   1 
ATOM   7222  O O   . VAL B 1 373 ? 107.282 148.562 122.558 1.00 73.89  ? 373 VAL B O   1 
ATOM   7223  C CB  . VAL B 1 373 ? 106.350 146.379 124.431 1.00 64.21  ? 373 VAL B CB  1 
ATOM   7224  C CG1 . VAL B 1 373 ? 105.151 145.553 124.881 1.00 68.05  ? 373 VAL B CG1 1 
ATOM   7225  C CG2 . VAL B 1 373 ? 107.598 145.890 125.147 1.00 68.50  ? 373 VAL B CG2 1 
ATOM   7226  N N   . VAL B 1 374 ? 108.712 146.940 121.996 1.00 68.31  ? 374 VAL B N   1 
ATOM   7227  C CA  . VAL B 1 374 ? 109.779 147.835 121.516 1.00 67.77  ? 374 VAL B CA  1 
ATOM   7228  C C   . VAL B 1 374 ? 109.740 148.066 120.000 1.00 74.31  ? 374 VAL B C   1 
ATOM   7229  O O   . VAL B 1 374 ? 110.596 148.766 119.465 1.00 78.48  ? 374 VAL B O   1 
ATOM   7230  C CB  . VAL B 1 374 ? 111.170 147.402 122.005 1.00 72.60  ? 374 VAL B CB  1 
ATOM   7231  C CG1 . VAL B 1 374 ? 111.226 147.388 123.530 1.00 76.06  ? 374 VAL B CG1 1 
ATOM   7232  C CG2 . VAL B 1 374 ? 111.614 146.037 121.491 1.00 69.89  ? 374 VAL B CG2 1 
ATOM   7233  N N   . LEU B 1 375 ? 108.730 147.579 119.267 1.00 69.84  ? 375 LEU B N   1 
ATOM   7234  C CA  . LEU B 1 375 ? 108.483 147.936 117.857 1.00 63.45  ? 375 LEU B CA  1 
ATOM   7235  C C   . LEU B 1 375 ? 107.803 149.305 117.705 1.00 67.28  ? 375 LEU B C   1 
ATOM   7236  O O   . LEU B 1 375 ? 107.012 149.683 118.555 1.00 78.47  ? 375 LEU B O   1 
ATOM   7237  C CB  . LEU B 1 375 ? 107.563 146.894 117.206 1.00 65.37  ? 375 LEU B CB  1 
ATOM   7238  C CG  . LEU B 1 375 ? 108.067 145.448 117.212 1.00 67.35  ? 375 LEU B CG  1 
ATOM   7239  C CD1 . LEU B 1 375 ? 107.074 144.587 116.447 1.00 65.25  ? 375 LEU B CD1 1 
ATOM   7240  C CD2 . LEU B 1 375 ? 109.432 145.331 116.559 1.00 66.72  ? 375 LEU B CD2 1 
ATOM   7241  N N   . GLU B 1 376 ? 108.012 150.036 116.610 1.00 70.56  ? 376 GLU B N   1 
ATOM   7242  C CA  . GLU B 1 376 ? 107.146 151.183 116.276 1.00 76.05  ? 376 GLU B CA  1 
ATOM   7243  C C   . GLU B 1 376 ? 105.826 150.725 115.627 1.00 74.54  ? 376 GLU B C   1 
ATOM   7244  O O   . GLU B 1 376 ? 105.834 149.751 114.879 1.00 76.41  ? 376 GLU B O   1 
ATOM   7245  C CB  . GLU B 1 376 ? 107.868 152.188 115.369 1.00 75.37  ? 376 GLU B CB  1 
ATOM   7246  C CG  . GLU B 1 376 ? 109.156 152.783 115.957 1.00 77.88  ? 376 GLU B CG  1 
ATOM   7247  C CD  . GLU B 1 376 ? 109.029 153.419 117.355 1.00 84.38  ? 376 GLU B CD  1 
ATOM   7248  O OE1 . GLU B 1 376 ? 107.916 153.798 117.775 1.00 90.91  ? 376 GLU B OE1 1 
ATOM   7249  O OE2 . GLU B 1 376 ? 110.074 153.531 118.036 1.00 82.97  ? 376 GLU B OE2 1 
ATOM   7250  N N   . PRO B 1 377 ? 104.689 151.402 115.875 1.00 60.92  ? 377 PRO B N   1 
ATOM   7251  C CA  . PRO B 1 377 ? 104.522 152.595 116.705 1.00 57.86  ? 377 PRO B CA  1 
ATOM   7252  C C   . PRO B 1 377 ? 104.454 152.326 118.217 1.00 67.26  ? 377 PRO B C   1 
ATOM   7253  O O   . PRO B 1 377 ? 104.424 153.279 118.984 1.00 79.49  ? 377 PRO B O   1 
ATOM   7254  C CB  . PRO B 1 377 ? 103.203 153.198 116.227 1.00 65.46  ? 377 PRO B CB  1 
ATOM   7255  C CG  . PRO B 1 377 ? 102.374 151.970 115.872 1.00 60.83  ? 377 PRO B CG  1 
ATOM   7256  C CD  . PRO B 1 377 ? 103.418 151.037 115.272 1.00 58.30  ? 377 PRO B CD  1 
ATOM   7257  N N   . LEU B 1 378 ? 104.398 151.069 118.671 1.00 70.54  ? 378 LEU B N   1 
ATOM   7258  C CA  . LEU B 1 378 ? 104.147 150.681 120.066 1.00 62.55  ? 378 LEU B CA  1 
ATOM   7259  C C   . LEU B 1 378 ? 105.131 151.301 121.061 1.00 66.86  ? 378 LEU B C   1 
ATOM   7260  O O   . LEU B 1 378 ? 104.712 151.782 122.105 1.00 75.14  ? 378 LEU B O   1 
ATOM   7261  C CB  . LEU B 1 378 ? 104.174 149.146 120.177 1.00 61.71  ? 378 LEU B CB  1 
ATOM   7262  C CG  . LEU B 1 378 ? 102.857 148.437 119.859 1.00 60.67  ? 378 LEU B CG  1 
ATOM   7263  C CD1 . LEU B 1 378 ? 102.257 148.807 118.532 1.00 63.63  ? 378 LEU B CD1 1 
ATOM   7264  C CD2 . LEU B 1 378 ? 103.074 146.944 119.875 1.00 65.71  ? 378 LEU B CD2 1 
ATOM   7265  N N   . ASN B 1 379 ? 106.415 151.347 120.737 1.00 66.18  ? 379 ASN B N   1 
ATOM   7266  C CA  . ASN B 1 379 ? 107.470 151.973 121.531 1.00 69.12  ? 379 ASN B CA  1 
ATOM   7267  C C   . ASN B 1 379 ? 107.203 153.463 121.805 1.00 72.00  ? 379 ASN B C   1 
ATOM   7268  O O   . ASN B 1 379 ? 107.092 153.845 122.973 1.00 77.25  ? 379 ASN B O   1 
ATOM   7269  C CB  . ASN B 1 379 ? 108.804 151.737 120.824 1.00 65.91  ? 379 ASN B CB  1 
ATOM   7270  C CG  . ASN B 1 379 ? 109.965 152.438 121.493 1.00 74.84  ? 379 ASN B CG  1 
ATOM   7271  O OD1 . ASN B 1 379 ? 110.157 152.367 122.701 1.00 78.41  ? 379 ASN B OD1 1 
ATOM   7272  N ND2 . ASN B 1 379 ? 110.755 153.155 120.734 1.00 74.98  ? 379 ASN B ND2 1 
ATOM   7273  N N   . LYS B 1 380 ? 107.031 154.303 120.773 1.00 69.47  ? 380 LYS B N   1 
ATOM   7274  C CA  . LYS B 1 380 ? 106.683 155.719 120.973 1.00 62.26  ? 380 LYS B CA  1 
ATOM   7275  C C   . LYS B 1 380 ? 105.287 155.895 121.580 1.00 66.16  ? 380 LYS B C   1 
ATOM   7276  O O   . LYS B 1 380 ? 105.106 156.766 122.417 1.00 76.22  ? 380 LYS B O   1 
ATOM   7277  C CB  . LYS B 1 380 ? 106.846 156.512 119.666 1.00 61.53  ? 380 LYS B CB  1 
ATOM   7278  C CG  . LYS B 1 380 ? 106.767 158.026 119.933 1.00 73.27  ? 380 LYS B CG  1 
ATOM   7279  C CD  . LYS B 1 380 ? 106.615 158.898 118.681 1.00 80.11  ? 380 LYS B CD  1 
ATOM   7280  C CE  . LYS B 1 380 ? 106.288 160.327 119.133 1.00 74.20  ? 380 LYS B CE  1 
ATOM   7281  N NZ  . LYS B 1 380 ? 106.089 161.262 118.001 1.00 63.73  ? 380 LYS B NZ  1 
ATOM   7282  N N   . LEU B 1 381 ? 104.311 155.062 121.235 1.00 61.22  ? 381 LEU B N   1 
ATOM   7283  C CA  . LEU B 1 381 ? 102.960 155.107 121.798 1.00 57.16  ? 381 LEU B CA  1 
ATOM   7284  C C   . LEU B 1 381 ? 102.919 154.792 123.306 1.00 65.36  ? 381 LEU B C   1 
ATOM   7285  O O   . LEU B 1 381 ? 102.193 155.440 124.053 1.00 72.56  ? 381 LEU B O   1 
ATOM   7286  C CB  . LEU B 1 381 ? 102.107 154.130 120.981 1.00 58.97  ? 381 LEU B CB  1 
ATOM   7287  C CG  . LEU B 1 381 ? 100.612 154.092 121.314 1.00 63.58  ? 381 LEU B CG  1 
ATOM   7288  C CD1 . LEU B 1 381 ? 99.951  155.443 121.072 1.00 63.77  ? 381 LEU B CD1 1 
ATOM   7289  C CD2 . LEU B 1 381 ? 99.946  153.070 120.405 1.00 64.14  ? 381 LEU B CD2 1 
ATOM   7290  N N   . LEU B 1 382 ? 103.715 153.834 123.786 1.00 62.74  ? 382 LEU B N   1 
ATOM   7291  C CA  . LEU B 1 382 ? 103.853 153.513 125.196 1.00 59.46  ? 382 LEU B CA  1 
ATOM   7292  C C   . LEU B 1 382 ? 104.724 154.532 125.930 1.00 63.14  ? 382 LEU B C   1 
ATOM   7293  O O   . LEU B 1 382 ? 104.464 154.796 127.096 1.00 71.67  ? 382 LEU B O   1 
ATOM   7294  C CB  . LEU B 1 382 ? 104.410 152.091 125.326 1.00 60.89  ? 382 LEU B CB  1 
ATOM   7295  C CG  . LEU B 1 382 ? 103.409 151.003 124.912 1.00 57.14  ? 382 LEU B CG  1 
ATOM   7296  C CD1 . LEU B 1 382 ? 104.151 149.690 124.718 1.00 55.24  ? 382 LEU B CD1 1 
ATOM   7297  C CD2 . LEU B 1 382 ? 102.320 150.835 125.965 1.00 66.99  ? 382 LEU B CD2 1 
ATOM   7298  N N   . GLN B 1 383 ? 105.707 155.153 125.276 1.00 66.78  ? 383 GLN B N   1 
ATOM   7299  C CA  . GLN B 1 383 ? 106.439 156.278 125.859 1.00 62.79  ? 383 GLN B CA  1 
ATOM   7300  C C   . GLN B 1 383 ? 105.538 157.502 126.050 1.00 70.93  ? 383 GLN B C   1 
ATOM   7301  O O   . GLN B 1 383 ? 105.555 158.120 127.103 1.00 80.68  ? 383 GLN B O   1 
ATOM   7302  C CB  . GLN B 1 383 ? 107.653 156.619 124.991 1.00 66.02  ? 383 GLN B CB  1 
ATOM   7303  C CG  . GLN B 1 383 ? 108.568 157.661 125.644 1.00 70.75  ? 383 GLN B CG  1 
ATOM   7304  C CD  . GLN B 1 383 ? 109.242 157.168 126.924 1.00 79.15  ? 383 GLN B CD  1 
ATOM   7305  O OE1 . GLN B 1 383 ? 109.823 156.090 126.978 1.00 84.66  ? 383 GLN B OE1 1 
ATOM   7306  N NE2 . GLN B 1 383 ? 109.216 157.919 127.994 1.00 73.97  ? 383 GLN B NE2 1 
ATOM   7307  N N   . GLU B 1 384 ? 104.717 157.839 125.059 1.00 69.62  ? 384 GLU B N   1 
ATOM   7308  C CA  . GLU B 1 384 ? 103.722 158.907 125.137 1.00 63.34  ? 384 GLU B CA  1 
ATOM   7309  C C   . GLU B 1 384 ? 102.712 158.681 126.266 1.00 71.67  ? 384 GLU B C   1 
ATOM   7310  O O   . GLU B 1 384 ? 102.428 159.598 127.028 1.00 75.12  ? 384 GLU B O   1 
ATOM   7311  C CB  . GLU B 1 384 ? 102.991 158.991 123.792 1.00 67.36  ? 384 GLU B CB  1 
ATOM   7312  C CG  . GLU B 1 384 ? 103.781 159.737 122.708 1.00 78.98  ? 384 GLU B CG  1 
ATOM   7313  C CD  . GLU B 1 384 ? 103.337 161.173 122.407 1.00 84.22  ? 384 GLU B CD  1 
ATOM   7314  O OE1 . GLU B 1 384 ? 102.281 161.639 122.891 1.00 86.08  ? 384 GLU B OE1 1 
ATOM   7315  O OE2 . GLU B 1 384 ? 104.052 161.846 121.652 1.00 77.41  ? 384 GLU B OE2 1 
ATOM   7316  N N   . LYS B 1 385 ? 102.200 157.457 126.430 1.00 77.50  ? 385 LYS B N   1 
ATOM   7317  C CA  . LYS B 1 385 ? 101.333 157.095 127.559 1.00 65.94  ? 385 LYS B CA  1 
ATOM   7318  C C   . LYS B 1 385 ? 102.073 157.158 128.894 1.00 65.41  ? 385 LYS B C   1 
ATOM   7319  O O   . LYS B 1 385 ? 101.537 157.697 129.854 1.00 72.13  ? 385 LYS B O   1 
ATOM   7320  C CB  . LYS B 1 385 ? 100.751 155.697 127.338 1.00 67.27  ? 385 LYS B CB  1 
ATOM   7321  C CG  . LYS B 1 385 ? 99.683  155.649 126.244 1.00 69.01  ? 385 LYS B CG  1 
ATOM   7322  C CD  . LYS B 1 385 ? 99.253  154.207 125.955 1.00 69.28  ? 385 LYS B CD  1 
ATOM   7323  C CE  . LYS B 1 385 ? 98.255  154.113 124.803 1.00 76.61  ? 385 LYS B CE  1 
ATOM   7324  N NZ  . LYS B 1 385 ? 96.994  154.815 125.080 1.00 66.90  ? 385 LYS B NZ  1 
ATOM   7325  N N   . TRP B 1 386 ? 103.301 156.652 128.977 1.00 65.35  ? 386 TRP B N   1 
ATOM   7326  C CA  . TRP B 1 386 ? 104.124 156.692 130.182 1.00 65.50  ? 386 TRP B CA  1 
ATOM   7327  C C   . TRP B 1 386 ? 104.387 158.122 130.643 1.00 66.38  ? 386 TRP B C   1 
ATOM   7328  O O   . TRP B 1 386 ? 104.156 158.445 131.797 1.00 75.97  ? 386 TRP B O   1 
ATOM   7329  C CB  . TRP B 1 386 ? 105.437 155.941 129.943 1.00 63.72  ? 386 TRP B CB  1 
ATOM   7330  C CG  . TRP B 1 386 ? 106.403 156.025 131.075 1.00 68.29  ? 386 TRP B CG  1 
ATOM   7331  C CD1 . TRP B 1 386 ? 107.496 156.816 131.120 1.00 69.23  ? 386 TRP B CD1 1 
ATOM   7332  C CD2 . TRP B 1 386 ? 106.308 155.396 132.383 1.00 73.63  ? 386 TRP B CD2 1 
ATOM   7333  N NE1 . TRP B 1 386 ? 108.089 156.710 132.362 1.00 70.90  ? 386 TRP B NE1 1 
ATOM   7334  C CE2 . TRP B 1 386 ? 107.381 155.867 133.188 1.00 73.13  ? 386 TRP B CE2 1 
ATOM   7335  C CE3 . TRP B 1 386 ? 105.393 154.513 132.986 1.00 70.63  ? 386 TRP B CE3 1 
ATOM   7336  C CZ2 . TRP B 1 386 ? 107.534 155.475 134.520 1.00 69.39  ? 386 TRP B CZ2 1 
ATOM   7337  C CZ3 . TRP B 1 386 ? 105.544 154.107 134.320 1.00 64.50  ? 386 TRP B CZ3 1 
ATOM   7338  C CH2 . TRP B 1 386 ? 106.612 154.582 135.085 1.00 68.30  ? 386 TRP B CH2 1 
ATOM   7339  N N   . ASP B 1 387 ? 104.765 159.018 129.743 1.00 66.34  ? 387 ASP B N   1 
ATOM   7340  C CA  . ASP B 1 387 ? 104.982 160.438 130.033 1.00 66.65  ? 387 ASP B CA  1 
ATOM   7341  C C   . ASP B 1 387 ? 103.722 161.136 130.578 1.00 69.13  ? 387 ASP B C   1 
ATOM   7342  O O   . ASP B 1 387 ? 103.823 162.002 131.442 1.00 75.06  ? 387 ASP B O   1 
ATOM   7343  C CB  . ASP B 1 387 ? 105.465 161.164 128.770 1.00 74.51  ? 387 ASP B CB  1 
ATOM   7344  C CG  . ASP B 1 387 ? 106.836 160.732 128.236 1.00 77.05  ? 387 ASP B CG  1 
ATOM   7345  O OD1 . ASP B 1 387 ? 107.592 160.026 128.938 1.00 71.85  ? 387 ASP B OD1 1 
ATOM   7346  O OD2 . ASP B 1 387 ? 107.195 161.174 127.123 1.00 75.68  ? 387 ASP B OD2 1 
ATOM   7347  N N   . ARG B 1 388 ? 102.526 160.765 130.106 1.00 80.32  ? 388 ARG B N   1 
ATOM   7348  C CA  . ARG B 1 388 ? 101.249 161.253 130.652 1.00 78.76  ? 388 ARG B CA  1 
ATOM   7349  C C   . ARG B 1 388 ? 100.895 160.670 132.021 1.00 85.00  ? 388 ARG B C   1 
ATOM   7350  O O   . ARG B 1 388 ? 100.001 161.245 132.671 1.00 83.99  ? 388 ARG B O   1 
ATOM   7351  C CB  . ARG B 1 388 ? 100.110 161.018 129.643 1.00 78.62  ? 388 ARG B CB  1 
ATOM   7352  C CG  . ARG B 1 388 ? 100.222 161.980 128.454 1.00 85.28  ? 388 ARG B CG  1 
ATOM   7353  C CD  . ARG B 1 388 ? 98.988  161.980 127.531 1.00 84.40  ? 388 ARG B CD  1 
ATOM   7354  N NE  . ARG B 1 388 ? 98.944  160.667 126.905 1.00 90.38  ? 388 ARG B NE  1 
ATOM   7355  C CZ  . ARG B 1 388 ? 99.754  160.282 125.925 1.00 95.63  ? 388 ARG B CZ  1 
ATOM   7356  N NH1 . ARG B 1 388 ? 99.657  159.062 125.425 1.00 90.77  ? 388 ARG B NH1 1 
ATOM   7357  N NH2 . ARG B 1 388 ? 100.666 161.113 125.455 1.00 90.09  ? 388 ARG B NH2 1 
ATOM   7358  N N   . LEU B 1 389 ? 101.539 159.585 132.454 1.00 78.44  ? 389 LEU B N   1 
ATOM   7359  C CA  . LEU B 1 389 ? 101.188 158.822 133.658 1.00 66.38  ? 389 LEU B CA  1 
ATOM   7360  C C   . LEU B 1 389 ? 102.316 158.700 134.692 1.00 70.34  ? 389 LEU B C   1 
ATOM   7361  O O   . LEU B 1 389 ? 102.048 158.276 135.808 1.00 81.19  ? 389 LEU B O   1 
ATOM   7362  C CB  . LEU B 1 389 ? 100.672 157.440 133.238 1.00 68.35  ? 389 LEU B CB  1 
ATOM   7363  C CG  . LEU B 1 389 ? 99.335  157.453 132.480 1.00 71.97  ? 389 LEU B CG  1 
ATOM   7364  C CD1 . LEU B 1 389 ? 99.089  156.090 131.851 1.00 71.14  ? 389 LEU B CD1 1 
ATOM   7365  C CD2 . LEU B 1 389 ? 98.164  157.774 133.404 1.00 66.83  ? 389 LEU B CD2 1 
ATOM   7366  N N   . VAL B 1 390 ? 103.551 159.108 134.401 1.00 71.13  ? 390 VAL B N   1 
ATOM   7367  C CA  . VAL B 1 390 ? 104.703 159.011 135.309 1.00 71.05  ? 390 VAL B CA  1 
ATOM   7368  C C   . VAL B 1 390 ? 104.479 159.755 136.635 1.00 76.47  ? 390 VAL B C   1 
ATOM   7369  O O   . VAL B 1 390 ? 104.863 159.276 137.696 1.00 78.84  ? 390 VAL B O   1 
ATOM   7370  C CB  . VAL B 1 390 ? 105.977 159.439 134.561 1.00 63.94  ? 390 VAL B CB  1 
ATOM   7371  C CG1 . VAL B 1 390 ? 106.002 160.921 134.192 1.00 67.98  ? 390 VAL B CG1 1 
ATOM   7372  C CG2 . VAL B 1 390 ? 107.236 159.129 135.360 1.00 69.65  ? 390 VAL B CG2 1 
ATOM   7373  N N   . SER B 1 391 ? 103.748 160.869 136.626 1.00 77.10  ? 391 SER B N   1 
ATOM   7374  C CA  . SER B 1 391 ? 103.330 161.585 137.838 1.00 70.17  ? 391 SER B CA  1 
ATOM   7375  C C   . SER B 1 391 ? 102.274 160.830 138.653 1.00 74.56  ? 391 SER B C   1 
ATOM   7376  O O   . SER B 1 391 ? 102.271 160.933 139.878 1.00 87.90  ? 391 SER B O   1 
ATOM   7377  C CB  . SER B 1 391 ? 102.797 162.965 137.457 1.00 73.69  ? 391 SER B CB  1 
ATOM   7378  O OG  . SER B 1 391 ? 101.687 162.847 136.589 1.00 81.83  ? 391 SER B OG  1 
ATOM   7379  N N   . ARG B 1 392 ? 101.426 160.013 138.021 1.00 74.12  ? 392 ARG B N   1 
ATOM   7380  C CA  . ARG B 1 392 ? 100.488 159.097 138.695 1.00 63.71  ? 392 ARG B CA  1 
ATOM   7381  C C   . ARG B 1 392 ? 101.222 157.892 139.274 1.00 71.05  ? 392 ARG B C   1 
ATOM   7382  O O   . ARG B 1 392 ? 100.945 157.487 140.392 1.00 88.30  ? 392 ARG B O   1 
ATOM   7383  C CB  . ARG B 1 392 ? 99.395  158.663 137.710 1.00 70.73  ? 392 ARG B CB  1 
ATOM   7384  C CG  . ARG B 1 392 ? 98.129  158.200 138.433 1.00 69.16  ? 392 ARG B CG  1 
ATOM   7385  C CD  . ARG B 1 392 ? 97.053  157.801 137.414 1.00 82.01  ? 392 ARG B CD  1 
ATOM   7386  N NE  . ARG B 1 392 ? 95.710  157.770 138.020 1.00 87.69  ? 392 ARG B NE  1 
ATOM   7387  C CZ  . ARG B 1 392 ? 94.890  158.796 138.174 1.00 92.58  ? 392 ARG B CZ  1 
ATOM   7388  N NH1 . ARG B 1 392 ? 93.714  158.635 138.704 1.00 88.09  ? 392 ARG B NH1 1 
ATOM   7389  N NH2 . ARG B 1 392 ? 95.203  160.003 137.807 1.00 88.13  ? 392 ARG B NH2 1 
ATOM   7390  N N   . PHE B 1 393 ? 102.220 157.371 138.571 1.00 62.33  ? 393 PHE B N   1 
ATOM   7391  C CA  . PHE B 1 393 ? 103.089 156.305 139.053 1.00 55.11  ? 393 PHE B CA  1 
ATOM   7392  C C   . PHE B 1 393 ? 103.832 156.715 140.325 1.00 65.53  ? 393 PHE B C   1 
ATOM   7393  O O   . PHE B 1 393 ? 103.808 155.988 141.314 1.00 77.66  ? 393 PHE B O   1 
ATOM   7394  C CB  . PHE B 1 393 ? 104.064 155.903 137.946 1.00 56.92  ? 393 PHE B CB  1 
ATOM   7395  C CG  . PHE B 1 393 ? 104.901 154.698 138.294 1.00 60.48  ? 393 PHE B CG  1 
ATOM   7396  C CD1 . PHE B 1 393 ? 104.379 153.407 138.100 1.00 67.83  ? 393 PHE B CD1 1 
ATOM   7397  C CD2 . PHE B 1 393 ? 106.194 154.854 138.819 1.00 57.70  ? 393 PHE B CD2 1 
ATOM   7398  C CE1 . PHE B 1 393 ? 105.154 152.283 138.414 1.00 62.48  ? 393 PHE B CE1 1 
ATOM   7399  C CE2 . PHE B 1 393 ? 106.964 153.728 139.136 1.00 62.25  ? 393 PHE B CE2 1 
ATOM   7400  C CZ  . PHE B 1 393 ? 106.448 152.443 138.919 1.00 58.32  ? 393 PHE B CZ  1 
ATOM   7401  N N   . PHE B 1 394 ? 104.444 157.903 140.349 1.00 71.25  ? 394 PHE B N   1 
ATOM   7402  C CA  . PHE B 1 394 ? 105.158 158.374 141.532 1.00 66.07  ? 394 PHE B CA  1 
ATOM   7403  C C   . PHE B 1 394 ? 104.255 158.911 142.650 1.00 62.38  ? 394 PHE B C   1 
ATOM   7404  O O   . PHE B 1 394 ? 104.619 158.803 143.814 1.00 77.72  ? 394 PHE B O   1 
ATOM   7405  C CB  . PHE B 1 394 ? 106.287 159.315 141.122 1.00 63.62  ? 394 PHE B CB  1 
ATOM   7406  C CG  . PHE B 1 394 ? 107.406 158.573 140.411 1.00 74.04  ? 394 PHE B CG  1 
ATOM   7407  C CD1 . PHE B 1 394 ? 108.112 157.564 141.088 1.00 72.56  ? 394 PHE B CD1 1 
ATOM   7408  C CD2 . PHE B 1 394 ? 107.727 158.857 139.074 1.00 66.45  ? 394 PHE B CD2 1 
ATOM   7409  C CE1 . PHE B 1 394 ? 109.118 156.834 140.439 1.00 69.15  ? 394 PHE B CE1 1 
ATOM   7410  C CE2 . PHE B 1 394 ? 108.744 158.138 138.426 1.00 65.36  ? 394 PHE B CE2 1 
ATOM   7411  C CZ  . PHE B 1 394 ? 109.439 157.132 139.108 1.00 70.08  ? 394 PHE B CZ  1 
ATOM   7412  N N   . PHE B 1 395 ? 103.051 159.392 142.353 1.00 60.95  ? 395 PHE B N   1 
ATOM   7413  C CA  . PHE B 1 395 ? 102.027 159.615 143.370 1.00 62.88  ? 395 PHE B CA  1 
ATOM   7414  C C   . PHE B 1 395 ? 101.617 158.303 144.049 1.00 69.35  ? 395 PHE B C   1 
ATOM   7415  O O   . PHE B 1 395 ? 101.617 158.215 145.275 1.00 81.93  ? 395 PHE B O   1 
ATOM   7416  C CB  . PHE B 1 395 ? 100.833 160.318 142.723 1.00 65.10  ? 395 PHE B CB  1 
ATOM   7417  C CG  . PHE B 1 395 ? 99.657  160.520 143.652 1.00 69.40  ? 395 PHE B CG  1 
ATOM   7418  C CD1 . PHE B 1 395 ? 99.727  161.476 144.677 1.00 75.73  ? 395 PHE B CD1 1 
ATOM   7419  C CD2 . PHE B 1 395 ? 98.492  159.756 143.488 1.00 69.17  ? 395 PHE B CD2 1 
ATOM   7420  C CE1 . PHE B 1 395 ? 98.635  161.666 145.537 1.00 73.63  ? 395 PHE B CE1 1 
ATOM   7421  C CE2 . PHE B 1 395 ? 97.396  159.956 144.339 1.00 74.04  ? 395 PHE B CE2 1 
ATOM   7422  C CZ  . PHE B 1 395 ? 97.466  160.911 145.363 1.00 74.80  ? 395 PHE B CZ  1 
ATOM   7423  N N   . ASN B 1 396 ? 101.353 157.247 143.281 1.00 69.09  ? 396 ASN B N   1 
ATOM   7424  C CA  . ASN B 1 396 ? 101.028 155.925 143.806 1.00 64.78  ? 396 ASN B CA  1 
ATOM   7425  C C   . ASN B 1 396 ? 102.151 155.340 144.685 1.00 70.02  ? 396 ASN B C   1 
ATOM   7426  O O   . ASN B 1 396 ? 101.874 154.753 145.728 1.00 77.50  ? 396 ASN B O   1 
ATOM   7427  C CB  . ASN B 1 396 ? 100.718 154.993 142.626 1.00 69.06  ? 396 ASN B CB  1 
ATOM   7428  C CG  . ASN B 1 396 ? 99.413  155.278 141.900 1.00 72.77  ? 396 ASN B CG  1 
ATOM   7429  O OD1 . ASN B 1 396 ? 98.652  156.182 142.204 1.00 75.36  ? 396 ASN B OD1 1 
ATOM   7430  N ND2 . ASN B 1 396 ? 99.073  154.460 140.936 1.00 73.51  ? 396 ASN B ND2 1 
ATOM   7431  N N   . PHE B 1 397 ? 103.411 155.552 144.306 1.00 58.12  ? 397 PHE B N   1 
ATOM   7432  C CA  . PHE B 1 397 ? 104.603 155.248 145.099 1.00 58.37  ? 397 PHE B CA  1 
ATOM   7433  C C   . PHE B 1 397 ? 104.693 156.052 146.400 1.00 65.29  ? 397 PHE B C   1 
ATOM   7434  O O   . PHE B 1 397 ? 104.969 155.474 147.445 1.00 73.03  ? 397 PHE B O   1 
ATOM   7435  C CB  . PHE B 1 397 ? 105.840 155.509 144.244 1.00 55.63  ? 397 PHE B CB  1 
ATOM   7436  C CG  . PHE B 1 397 ? 107.171 155.441 144.968 1.00 64.70  ? 397 PHE B CG  1 
ATOM   7437  C CD1 . PHE B 1 397 ? 107.561 154.270 145.636 1.00 64.79  ? 397 PHE B CD1 1 
ATOM   7438  C CD2 . PHE B 1 397 ? 108.031 156.552 144.963 1.00 69.09  ? 397 PHE B CD2 1 
ATOM   7439  C CE1 . PHE B 1 397 ? 108.815 154.191 146.252 1.00 56.18  ? 397 PHE B CE1 1 
ATOM   7440  C CE2 . PHE B 1 397 ? 109.280 156.481 145.597 1.00 67.92  ? 397 PHE B CE2 1 
ATOM   7441  C CZ  . PHE B 1 397 ? 109.675 155.297 146.232 1.00 65.24  ? 397 PHE B CZ  1 
ATOM   7442  N N   . ALA B 1 398 ? 104.439 157.362 146.373 1.00 69.65  ? 398 ALA B N   1 
ATOM   7443  C CA  . ALA B 1 398 ? 104.457 158.216 147.555 1.00 56.41  ? 398 ALA B CA  1 
ATOM   7444  C C   . ALA B 1 398 ? 103.345 157.867 148.557 1.00 62.99  ? 398 ALA B C   1 
ATOM   7445  O O   . ALA B 1 398 ? 103.605 157.815 149.754 1.00 83.39  ? 398 ALA B O   1 
ATOM   7446  C CB  . ALA B 1 398 ? 104.375 159.670 147.104 1.00 55.94  ? 398 ALA B CB  1 
ATOM   7447  N N   . CYS B 1 399 ? 102.131 157.544 148.109 1.00 59.27  ? 399 CYS B N   1 
ATOM   7448  C CA  . CYS B 1 399 ? 101.092 157.004 148.990 1.00 67.71  ? 399 CYS B CA  1 
ATOM   7449  C C   . CYS B 1 399 ? 101.526 155.697 149.661 1.00 66.36  ? 399 CYS B C   1 
ATOM   7450  O O   . CYS B 1 399 ? 101.289 155.512 150.851 1.00 76.94  ? 399 CYS B O   1 
ATOM   7451  C CB  . CYS B 1 399 ? 99.824  156.752 148.182 1.00 71.04  ? 399 CYS B CB  1 
ATOM   7452  S SG  . CYS B 1 399 ? 99.059  158.305 147.688 1.00 72.59  ? 399 CYS B SG  1 
ATOM   7453  N N   . TYR B 1 400 ? 102.184 154.819 148.912 1.00 54.62  ? 400 TYR B N   1 
ATOM   7454  C CA  . TYR B 1 400 ? 102.653 153.552 149.438 1.00 51.92  ? 400 TYR B CA  1 
ATOM   7455  C C   . TYR B 1 400 ? 103.851 153.727 150.384 1.00 65.12  ? 400 TYR B C   1 
ATOM   7456  O O   . TYR B 1 400 ? 103.911 153.057 151.405 1.00 80.26  ? 400 TYR B O   1 
ATOM   7457  C CB  . TYR B 1 400 ? 102.933 152.614 148.275 1.00 57.47  ? 400 TYR B CB  1 
ATOM   7458  C CG  . TYR B 1 400 ? 103.157 151.194 148.729 1.00 62.86  ? 400 TYR B CG  1 
ATOM   7459  C CD1 . TYR B 1 400 ? 102.066 150.368 149.039 1.00 59.80  ? 400 TYR B CD1 1 
ATOM   7460  C CD2 . TYR B 1 400 ? 104.465 150.726 148.895 1.00 57.33  ? 400 TYR B CD2 1 
ATOM   7461  C CE1 . TYR B 1 400 ? 102.294 149.072 149.529 1.00 51.09  ? 400 TYR B CE1 1 
ATOM   7462  C CE2 . TYR B 1 400 ? 104.701 149.434 149.372 1.00 50.80  ? 400 TYR B CE2 1 
ATOM   7463  C CZ  . TYR B 1 400 ? 103.609 148.614 149.698 1.00 53.91  ? 400 TYR B CZ  1 
ATOM   7464  O OH  . TYR B 1 400 ? 103.833 147.396 150.224 1.00 66.93  ? 400 TYR B OH  1 
ATOM   7465  N N   . LEU B 1 401 ? 104.750 154.688 150.152 1.00 55.25  ? 401 LEU B N   1 
ATOM   7466  C CA  . LEU B 1 401 ? 105.769 155.096 151.118 1.00 48.34  ? 401 LEU B CA  1 
ATOM   7467  C C   . LEU B 1 401 ? 105.151 155.607 152.424 1.00 55.61  ? 401 LEU B C   1 
ATOM   7468  O O   . LEU B 1 401 ? 105.584 155.209 153.494 1.00 71.64  ? 401 LEU B O   1 
ATOM   7469  C CB  . LEU B 1 401 ? 106.632 156.228 150.543 1.00 63.08  ? 401 LEU B CB  1 
ATOM   7470  C CG  . LEU B 1 401 ? 107.824 155.823 149.686 1.00 66.12  ? 401 LEU B CG  1 
ATOM   7471  C CD1 . LEU B 1 401 ? 108.452 157.097 149.128 1.00 62.24  ? 401 LEU B CD1 1 
ATOM   7472  C CD2 . LEU B 1 401 ? 108.895 155.114 150.510 1.00 62.20  ? 401 LEU B CD2 1 
ATOM   7473  N N   . VAL B 1 402 ? 104.147 156.479 152.364 1.00 58.65  ? 402 VAL B N   1 
ATOM   7474  C CA  . VAL B 1 402 ? 103.447 157.018 153.541 1.00 62.73  ? 402 VAL B CA  1 
ATOM   7475  C C   . VAL B 1 402 ? 102.714 155.920 154.304 1.00 64.13  ? 402 VAL B C   1 
ATOM   7476  O O   . VAL B 1 402 ? 102.793 155.870 155.524 1.00 74.10  ? 402 VAL B O   1 
ATOM   7477  C CB  . VAL B 1 402 ? 102.496 158.158 153.139 1.00 62.15  ? 402 VAL B CB  1 
ATOM   7478  C CG1 . VAL B 1 402 ? 101.574 158.588 154.281 1.00 69.06  ? 402 VAL B CG1 1 
ATOM   7479  C CG2 . VAL B 1 402 ? 103.309 159.380 152.714 1.00 57.83  ? 402 VAL B CG2 1 
ATOM   7480  N N   . TYR B 1 403 ? 102.040 155.006 153.605 1.00 64.93  ? 403 TYR B N   1 
ATOM   7481  C CA  . TYR B 1 403 ? 101.447 153.810 154.195 1.00 56.12  ? 403 TYR B CA  1 
ATOM   7482  C C   . TYR B 1 403 ? 102.512 152.932 154.857 1.00 61.37  ? 403 TYR B C   1 
ATOM   7483  O O   . TYR B 1 403 ? 102.334 152.554 156.007 1.00 79.53  ? 403 TYR B O   1 
ATOM   7484  C CB  . TYR B 1 403 ? 100.655 153.061 153.118 1.00 67.58  ? 403 TYR B CB  1 
ATOM   7485  C CG  . TYR B 1 403 ? 100.240 151.633 153.430 1.00 70.42  ? 403 TYR B CG  1 
ATOM   7486  C CD1 . TYR B 1 403 ? 99.185  151.362 154.323 1.00 61.54  ? 403 TYR B CD1 1 
ATOM   7487  C CD2 . TYR B 1 403 ? 100.882 150.570 152.771 1.00 72.54  ? 403 TYR B CD2 1 
ATOM   7488  C CE1 . TYR B 1 403 ? 98.770  150.033 154.543 1.00 58.00  ? 403 TYR B CE1 1 
ATOM   7489  C CE2 . TYR B 1 403 ? 100.473 149.245 152.988 1.00 66.42  ? 403 TYR B CE2 1 
ATOM   7490  C CZ  . TYR B 1 403 ? 99.406  148.975 153.865 1.00 63.57  ? 403 TYR B CZ  1 
ATOM   7491  O OH  . TYR B 1 403 ? 98.979  147.700 154.036 1.00 74.72  ? 403 TYR B OH  1 
ATOM   7492  N N   . MET B 1 404 ? 103.652 152.674 154.212 1.00 55.75  ? 404 MET B N   1 
ATOM   7493  C CA  . MET B 1 404 ? 104.742 151.896 154.811 1.00 65.40  ? 404 MET B CA  1 
ATOM   7494  C C   . MET B 1 404 ? 105.506 152.613 155.932 1.00 70.48  ? 404 MET B C   1 
ATOM   7495  O O   . MET B 1 404 ? 105.993 151.954 156.849 1.00 78.00  ? 404 MET B O   1 
ATOM   7496  C CB  . MET B 1 404 ? 105.705 151.391 153.730 1.00 54.05  ? 404 MET B CB  1 
ATOM   7497  C CG  . MET B 1 404 ? 105.111 150.246 152.908 1.00 61.50  ? 404 MET B CG  1 
ATOM   7498  S SD  . MET B 1 404 ? 104.372 148.865 153.831 1.00 63.28  ? 404 MET B SD  1 
ATOM   7499  C CE  . MET B 1 404 ? 105.694 148.446 154.987 1.00 69.76  ? 404 MET B CE  1 
ATOM   7500  N N   . PHE B 1 405 ? 105.567 153.940 155.937 1.00 66.03  ? 405 PHE B N   1 
ATOM   7501  C CA  . PHE B 1 405 ? 106.060 154.723 157.068 1.00 65.96  ? 405 PHE B CA  1 
ATOM   7502  C C   . PHE B 1 405 ? 105.149 154.551 158.291 1.00 68.62  ? 405 PHE B C   1 
ATOM   7503  O O   . PHE B 1 405 ? 105.620 154.130 159.344 1.00 73.67  ? 405 PHE B O   1 
ATOM   7504  C CB  . PHE B 1 405 ? 106.193 156.189 156.644 1.00 62.93  ? 405 PHE B CB  1 
ATOM   7505  C CG  . PHE B 1 405 ? 106.607 157.130 157.754 1.00 77.51  ? 405 PHE B CG  1 
ATOM   7506  C CD1 . PHE B 1 405 ? 107.965 157.321 158.053 1.00 78.09  ? 405 PHE B CD1 1 
ATOM   7507  C CD2 . PHE B 1 405 ? 105.628 157.808 158.501 1.00 80.06  ? 405 PHE B CD2 1 
ATOM   7508  C CE1 . PHE B 1 405 ? 108.346 158.173 159.103 1.00 77.43  ? 405 PHE B CE1 1 
ATOM   7509  C CE2 . PHE B 1 405 ? 106.006 158.651 159.557 1.00 75.06  ? 405 PHE B CE2 1 
ATOM   7510  C CZ  . PHE B 1 405 ? 107.365 158.834 159.858 1.00 75.07  ? 405 PHE B CZ  1 
ATOM   7511  N N   . ILE B 1 406 ? 103.839 154.775 158.142 1.00 68.69  ? 406 ILE B N   1 
ATOM   7512  C CA  . ILE B 1 406 ? 102.823 154.556 159.175 1.00 65.33  ? 406 ILE B CA  1 
ATOM   7513  C C   . ILE B 1 406 ? 102.842 153.098 159.647 1.00 69.17  ? 406 ILE B C   1 
ATOM   7514  O O   . ILE B 1 406 ? 102.868 152.858 160.847 1.00 87.94  ? 406 ILE B O   1 
ATOM   7515  C CB  . ILE B 1 406 ? 101.431 154.993 158.670 1.00 67.21  ? 406 ILE B CB  1 
ATOM   7516  C CG1 . ILE B 1 406 ? 101.395 156.518 158.450 1.00 68.58  ? 406 ILE B CG1 1 
ATOM   7517  C CG2 . ILE B 1 406 ? 100.315 154.588 159.642 1.00 68.28  ? 406 ILE B CG2 1 
ATOM   7518  C CD1 . ILE B 1 406 ? 100.237 156.974 157.563 1.00 74.99  ? 406 ILE B CD1 1 
ATOM   7519  N N   . PHE B 1 407 ? 102.913 152.123 158.740 1.00 60.96  ? 407 PHE B N   1 
ATOM   7520  C CA  . PHE B 1 407 ? 103.027 150.710 159.092 1.00 67.32  ? 407 PHE B CA  1 
ATOM   7521  C C   . PHE B 1 407 ? 104.238 150.463 159.992 1.00 79.83  ? 407 PHE B C   1 
ATOM   7522  O O   . PHE B 1 407 ? 104.140 149.771 161.000 1.00 84.43  ? 407 PHE B O   1 
ATOM   7523  C CB  . PHE B 1 407 ? 103.110 149.871 157.811 1.00 71.22  ? 407 PHE B CB  1 
ATOM   7524  C CG  . PHE B 1 407 ? 102.488 148.497 157.896 1.00 76.40  ? 407 PHE B CG  1 
ATOM   7525  C CD1 . PHE B 1 407 ? 102.970 147.525 158.787 1.00 75.16  ? 407 PHE B CD1 1 
ATOM   7526  C CD2 . PHE B 1 407 ? 101.402 148.189 157.068 1.00 76.93  ? 407 PHE B CD2 1 
ATOM   7527  C CE1 . PHE B 1 407 ? 102.368 146.262 158.846 1.00 73.49  ? 407 PHE B CE1 1 
ATOM   7528  C CE2 . PHE B 1 407 ? 100.799 146.931 157.135 1.00 74.88  ? 407 PHE B CE2 1 
ATOM   7529  C CZ  . PHE B 1 407 ? 101.275 145.965 158.025 1.00 70.98  ? 407 PHE B CZ  1 
ATOM   7530  N N   . THR B 1 408 ? 105.383 151.061 159.671 1.00 75.99  ? 408 THR B N   1 
ATOM   7531  C CA  . THR B 1 408 ? 106.635 150.869 160.411 1.00 73.29  ? 408 THR B CA  1 
ATOM   7532  C C   . THR B 1 408 ? 106.619 151.538 161.786 1.00 73.79  ? 408 THR B C   1 
ATOM   7533  O O   . THR B 1 408 ? 107.002 150.906 162.760 1.00 79.83  ? 408 THR B O   1 
ATOM   7534  C CB  . THR B 1 408 ? 107.810 151.368 159.567 1.00 67.06  ? 408 THR B CB  1 
ATOM   7535  O OG1 . THR B 1 408 ? 107.799 150.686 158.341 1.00 69.35  ? 408 THR B OG1 1 
ATOM   7536  C CG2 . THR B 1 408 ? 109.168 151.113 160.198 1.00 64.39  ? 408 THR B CG2 1 
ATOM   7537  N N   . VAL B 1 409 ? 106.125 152.773 161.885 1.00 66.22  ? 409 VAL B N   1 
ATOM   7538  C CA  . VAL B 1 409 ? 105.964 153.588 163.091 1.00 68.55  ? 409 VAL B CA  1 
ATOM   7539  C C   . VAL B 1 409 ? 104.905 153.023 164.042 1.00 71.93  ? 409 VAL B C   1 
ATOM   7540  O O   . VAL B 1 409 ? 104.911 153.397 165.210 1.00 83.55  ? 409 VAL B O   1 
ATOM   7541  C CB  . VAL B 1 409 ? 105.679 155.043 162.668 1.00 74.79  ? 409 VAL B CB  1 
ATOM   7542  C CG1 . VAL B 1 409 ? 105.227 155.990 163.779 1.00 76.28  ? 409 VAL B CG1 1 
ATOM   7543  C CG2 . VAL B 1 409 ? 106.964 155.643 162.089 1.00 70.40  ? 409 VAL B CG2 1 
ATOM   7544  N N   . VAL B 1 410 ? 104.019 152.146 163.563 1.00 72.91  ? 410 VAL B N   1 
ATOM   7545  C CA  . VAL B 1 410 ? 103.015 151.415 164.355 1.00 79.45  ? 410 VAL B CA  1 
ATOM   7546  C C   . VAL B 1 410 ? 103.438 149.983 164.687 1.00 83.70  ? 410 VAL B C   1 
ATOM   7547  O O   . VAL B 1 410 ? 102.997 149.451 165.697 1.00 88.03  ? 410 VAL B O   1 
ATOM   7548  C CB  . VAL B 1 410 ? 101.667 151.408 163.616 1.00 76.40  ? 410 VAL B CB  1 
ATOM   7549  C CG1 . VAL B 1 410 ? 100.591 150.530 164.259 1.00 80.44  ? 410 VAL B CG1 1 
ATOM   7550  C CG2 . VAL B 1 410 ? 101.085 152.819 163.542 1.00 74.72  ? 410 VAL B CG2 1 
ATOM   7551  N N   . ALA B 1 411 ? 104.272 149.328 163.872 1.00 80.78  ? 411 ALA B N   1 
ATOM   7552  C CA  . ALA B 1 411 ? 104.843 148.018 164.189 1.00 78.05  ? 411 ALA B CA  1 
ATOM   7553  C C   . ALA B 1 411 ? 106.026 148.134 165.170 1.00 86.76  ? 411 ALA B C   1 
ATOM   7554  O O   . ALA B 1 411 ? 106.088 147.426 166.177 1.00 90.52  ? 411 ALA B O   1 
ATOM   7555  C CB  . ALA B 1 411 ? 105.233 147.331 162.882 1.00 72.12  ? 411 ALA B CB  1 
ATOM   7556  N N   . TYR B 1 412 ? 106.930 149.087 164.939 1.00 88.66  ? 412 TYR B N   1 
ATOM   7557  C CA  . TYR B 1 412 ? 107.696 149.704 166.017 1.00 84.02  ? 412 TYR B CA  1 
ATOM   7558  C C   . TYR B 1 412 ? 106.705 150.486 166.912 1.00 90.25  ? 412 TYR B C   1 
ATOM   7559  O O   . TYR B 1 412 ? 105.609 150.813 166.473 1.00 93.36  ? 412 TYR B O   1 
ATOM   7560  C CB  . TYR B 1 412 ? 108.788 150.578 165.379 1.00 84.90  ? 412 TYR B CB  1 
ATOM   7561  C CG  . TYR B 1 412 ? 109.974 150.914 166.260 1.00 92.19  ? 412 TYR B CG  1 
ATOM   7562  C CD1 . TYR B 1 412 ? 109.920 152.025 167.111 1.00 93.54  ? 412 TYR B CD1 1 
ATOM   7563  C CD2 . TYR B 1 412 ? 111.155 150.157 166.181 1.00 91.17  ? 412 TYR B CD2 1 
ATOM   7564  C CE1 . TYR B 1 412 ? 111.034 152.386 167.886 1.00 92.13  ? 412 TYR B CE1 1 
ATOM   7565  C CE2 . TYR B 1 412 ? 112.280 150.518 166.948 1.00 89.83  ? 412 TYR B CE2 1 
ATOM   7566  C CZ  . TYR B 1 412 ? 112.223 151.643 167.795 1.00 93.93  ? 412 TYR B CZ  1 
ATOM   7567  O OH  . TYR B 1 412 ? 113.300 152.028 168.528 1.00 92.31  ? 412 TYR B OH  1 
ATOM   7568  N N   . HIS B 1 413 ? 107.015 150.773 168.173 1.00 97.67  ? 413 HIS B N   1 
ATOM   7569  C CA  . HIS B 1 413 ? 106.059 151.363 169.132 1.00 100.46 ? 413 HIS B CA  1 
ATOM   7570  C C   . HIS B 1 413 ? 104.784 150.536 169.432 1.00 100.85 ? 413 HIS B C   1 
ATOM   7571  O O   . HIS B 1 413 ? 103.838 151.073 170.007 1.00 102.82 ? 413 HIS B O   1 
ATOM   7572  C CB  . HIS B 1 413 ? 105.687 152.821 168.799 1.00 93.58  ? 413 HIS B CB  1 
ATOM   7573  C CG  . HIS B 1 413 ? 106.793 153.719 168.333 1.00 96.33  ? 413 HIS B CG  1 
ATOM   7574  N ND1 . HIS B 1 413 ? 106.910 154.226 167.065 1.00 98.91  ? 413 HIS B ND1 1 
ATOM   7575  C CD2 . HIS B 1 413 ? 107.773 154.297 169.088 1.00 99.33  ? 413 HIS B CD2 1 
ATOM   7576  C CE1 . HIS B 1 413 ? 107.932 155.092 167.043 1.00 100.32 ? 413 HIS B CE1 1 
ATOM   7577  N NE2 . HIS B 1 413 ? 108.498 155.166 168.259 1.00 100.91 ? 413 HIS B NE2 1 
ATOM   7578  N N   . GLN B 1 414 ? 104.743 149.229 169.139 1.00 99.43  ? 414 GLN B N   1 
ATOM   7579  C CA  . GLN B 1 414 ? 103.720 148.345 169.717 1.00 100.79 ? 414 GLN B CA  1 
ATOM   7580  C C   . GLN B 1 414 ? 103.856 148.286 171.252 1.00 109.94 ? 414 GLN B C   1 
ATOM   7581  O O   . GLN B 1 414 ? 104.982 148.293 171.764 1.00 107.66 ? 414 GLN B O   1 
ATOM   7582  C CB  . GLN B 1 414 ? 103.811 146.916 169.153 1.00 98.31  ? 414 GLN B CB  1 
ATOM   7583  C CG  . GLN B 1 414 ? 103.186 146.756 167.768 1.00 100.12 ? 414 GLN B CG  1 
ATOM   7584  C CD  . GLN B 1 414 ? 101.677 146.961 167.779 1.00 105.78 ? 414 GLN B CD  1 
ATOM   7585  O OE1 . GLN B 1 414 ? 100.921 146.180 168.331 1.00 107.67 ? 414 GLN B OE1 1 
ATOM   7586  N NE2 . GLN B 1 414 ? 101.188 148.011 167.178 1.00 104.06 ? 414 GLN B NE2 1 
ATOM   7587  N N   . PRO B 1 415 ? 102.746 148.192 172.005 1.00 121.57 ? 415 PRO B N   1 
ATOM   7588  C CA  . PRO B 1 415 ? 102.772 148.004 173.450 1.00 116.29 ? 415 PRO B CA  1 
ATOM   7589  C C   . PRO B 1 415 ? 103.185 146.573 173.831 1.00 116.14 ? 415 PRO B C   1 
ATOM   7590  O O   . PRO B 1 415 ? 103.174 145.663 173.000 1.00 112.02 ? 415 PRO B O   1 
ATOM   7591  C CB  . PRO B 1 415 ? 101.351 148.330 173.910 1.00 114.52 ? 415 PRO B CB  1 
ATOM   7592  C CG  . PRO B 1 415 ? 100.498 147.882 172.729 1.00 114.62 ? 415 PRO B CG  1 
ATOM   7593  C CD  . PRO B 1 415 ? 101.374 148.224 171.528 1.00 116.43 ? 415 PRO B CD  1 
ATOM   7594  N N   . SER B 1 416 ? 103.518 146.360 175.103 1.00 124.40 ? 416 SER B N   1 
ATOM   7595  C CA  . SER B 1 416 ? 103.782 145.027 175.661 1.00 126.27 ? 416 SER B CA  1 
ATOM   7596  C C   . SER B 1 416 ? 102.560 144.106 175.545 1.00 125.42 ? 416 SER B C   1 
ATOM   7597  O O   . SER B 1 416 ? 101.419 144.557 175.632 1.00 123.39 ? 416 SER B O   1 
ATOM   7598  C CB  . SER B 1 416 ? 104.202 145.128 177.127 1.00 125.23 ? 416 SER B CB  1 
ATOM   7599  O OG  . SER B 1 416 ? 105.289 146.025 177.267 1.00 122.52 ? 416 SER B OG  1 
ATOM   7600  N N   . LEU B 1 417 ? 102.782 142.806 175.363 1.00 125.30 ? 417 LEU B N   1 
ATOM   7601  C CA  . LEU B 1 417 ? 101.765 141.851 174.911 1.00 126.14 ? 417 LEU B CA  1 
ATOM   7602  C C   . LEU B 1 417 ? 101.931 140.513 175.636 1.00 123.13 ? 417 LEU B C   1 
ATOM   7603  O O   . LEU B 1 417 ? 100.945 139.846 175.967 1.00 120.08 ? 417 LEU B O   1 
ATOM   7604  C CB  . LEU B 1 417 ? 101.895 141.732 173.377 1.00 125.06 ? 417 LEU B CB  1 
ATOM   7605  C CG  . LEU B 1 417 ? 101.001 140.686 172.695 1.00 124.70 ? 417 LEU B CG  1 
ATOM   7606  C CD1 . LEU B 1 417 ? 99.528  141.030 172.867 1.00 122.84 ? 417 LEU B CD1 1 
ATOM   7607  C CD2 . LEU B 1 417 ? 101.343 140.626 171.207 1.00 120.43 ? 417 LEU B CD2 1 
ATOM   7608  N N   . PHE B 1 429 ? 98.438  161.204 174.559 1.00 127.92 ? 429 PHE B N   1 
ATOM   7609  C CA  . PHE B 1 429 ? 98.393  161.485 173.128 1.00 131.16 ? 429 PHE B CA  1 
ATOM   7610  C C   . PHE B 1 429 ? 98.995  160.343 172.296 1.00 132.75 ? 429 PHE B C   1 
ATOM   7611  O O   . PHE B 1 429 ? 98.460  159.976 171.251 1.00 130.26 ? 429 PHE B O   1 
ATOM   7612  C CB  . PHE B 1 429 ? 99.130  162.803 172.870 1.00 129.67 ? 429 PHE B CB  1 
ATOM   7613  C CG  . PHE B 1 429 ? 99.271  163.194 171.411 1.00 130.30 ? 429 PHE B CG  1 
ATOM   7614  C CD1 . PHE B 1 429 ? 98.154  163.642 170.690 1.00 129.80 ? 429 PHE B CD1 1 
ATOM   7615  C CD2 . PHE B 1 429 ? 100.527 163.141 170.783 1.00 131.03 ? 429 PHE B CD2 1 
ATOM   7616  C CE1 . PHE B 1 429 ? 98.293  164.037 169.350 1.00 130.68 ? 429 PHE B CE1 1 
ATOM   7617  C CE2 . PHE B 1 429 ? 100.666 163.545 169.445 1.00 131.18 ? 429 PHE B CE2 1 
ATOM   7618  C CZ  . PHE B 1 429 ? 99.552  163.995 168.728 1.00 131.08 ? 429 PHE B CZ  1 
ATOM   7619  N N   . GLY B 1 430 ? 100.072 159.720 172.776 1.00 130.45 ? 430 GLY B N   1 
ATOM   7620  C CA  . GLY B 1 430 ? 100.734 158.618 172.073 1.00 127.16 ? 430 GLY B CA  1 
ATOM   7621  C C   . GLY B 1 430 ? 99.821  157.406 171.850 1.00 129.67 ? 430 GLY B C   1 
ATOM   7622  O O   . GLY B 1 430 ? 99.879  156.781 170.794 1.00 131.89 ? 430 GLY B O   1 
ATOM   7623  N N   . GLU B 1 431 ? 98.929  157.101 172.791 1.00 126.26 ? 431 GLU B N   1 
ATOM   7624  C CA  . GLU B 1 431 ? 97.985  155.986 172.685 1.00 123.51 ? 431 GLU B CA  1 
ATOM   7625  C C   . GLU B 1 431 ? 96.860  156.229 171.669 1.00 126.03 ? 431 GLU B C   1 
ATOM   7626  O O   . GLU B 1 431 ? 96.496  155.313 170.931 1.00 125.58 ? 431 GLU B O   1 
ATOM   7627  C CB  . GLU B 1 431 ? 97.389  155.715 174.061 1.00 123.23 ? 431 GLU B CB  1 
ATOM   7628  N N   . SER B 1 432 ? 96.320  157.449 171.569 1.00 124.57 ? 432 SER B N   1 
ATOM   7629  C CA  . SER B 1 432 ? 95.307  157.771 170.552 1.00 124.71 ? 432 SER B CA  1 
ATOM   7630  C C   . SER B 1 432 ? 95.924  157.910 169.157 1.00 123.61 ? 432 SER B C   1 
ATOM   7631  O O   . SER B 1 432 ? 95.326  157.456 168.186 1.00 121.10 ? 432 SER B O   1 
ATOM   7632  C CB  . SER B 1 432 ? 94.503  159.015 170.930 1.00 124.59 ? 432 SER B CB  1 
ATOM   7633  O OG  . SER B 1 432 ? 95.312  160.167 170.978 1.00 126.04 ? 432 SER B OG  1 
ATOM   7634  N N   . MET B 1 433 ? 97.153  158.420 169.034 1.00 119.73 ? 433 MET B N   1 
ATOM   7635  C CA  . MET B 1 433 ? 97.902  158.380 167.771 1.00 117.77 ? 433 MET B CA  1 
ATOM   7636  C C   . MET B 1 433 ? 98.279  156.955 167.348 1.00 116.59 ? 433 MET B C   1 
ATOM   7637  O O   . MET B 1 433 ? 98.254  156.651 166.157 1.00 117.79 ? 433 MET B O   1 
ATOM   7638  C CB  . MET B 1 433 ? 99.157  159.253 167.860 1.00 118.17 ? 433 MET B CB  1 
ATOM   7639  C CG  . MET B 1 433 ? 98.811  160.742 167.946 1.00 122.27 ? 433 MET B CG  1 
ATOM   7640  S SD  . MET B 1 433 ? 97.877  161.423 166.546 1.00 128.14 ? 433 MET B SD  1 
ATOM   7641  C CE  . MET B 1 433 ? 99.131  161.323 165.249 1.00 118.10 ? 433 MET B CE  1 
ATOM   7642  N N   . LEU B 1 434 ? 98.568  156.046 168.281 1.00 111.55 ? 434 LEU B N   1 
ATOM   7643  C CA  . LEU B 1 434 ? 98.738  154.624 167.969 1.00 110.24 ? 434 LEU B CA  1 
ATOM   7644  C C   . LEU B 1 434 ? 97.430  154.007 167.459 1.00 112.54 ? 434 LEU B C   1 
ATOM   7645  O O   . LEU B 1 434 ? 97.447  153.295 166.457 1.00 115.42 ? 434 LEU B O   1 
ATOM   7646  C CB  . LEU B 1 434 ? 99.284  153.877 169.198 1.00 110.04 ? 434 LEU B CB  1 
ATOM   7647  C CG  . LEU B 1 434 ? 99.410  152.357 169.004 1.00 111.05 ? 434 LEU B CG  1 
ATOM   7648  C CD1 . LEU B 1 434 ? 100.454 152.004 167.951 1.00 110.75 ? 434 LEU B CD1 1 
ATOM   7649  C CD2 . LEU B 1 434 ? 99.799  151.685 170.314 1.00 112.38 ? 434 LEU B CD2 1 
ATOM   7650  N N   . LEU B 1 435 ? 96.287  154.293 168.094 1.00 110.77 ? 435 LEU B N   1 
ATOM   7651  C CA  . LEU B 1 435 ? 94.988  153.818 167.604 1.00 111.60 ? 435 LEU B CA  1 
ATOM   7652  C C   . LEU B 1 435 ? 94.669  154.355 166.198 1.00 108.60 ? 435 LEU B C   1 
ATOM   7653  O O   . LEU B 1 435 ? 94.272  153.582 165.329 1.00 106.05 ? 435 LEU B O   1 
ATOM   7654  C CB  . LEU B 1 435 ? 93.895  154.186 168.623 1.00 113.83 ? 435 LEU B CB  1 
ATOM   7655  C CG  . LEU B 1 435 ? 92.473  153.754 168.221 1.00 113.99 ? 435 LEU B CG  1 
ATOM   7656  C CD1 . LEU B 1 435 ? 92.358  152.239 168.053 1.00 109.57 ? 435 LEU B CD1 1 
ATOM   7657  C CD2 . LEU B 1 435 ? 91.495  154.200 169.304 1.00 109.92 ? 435 LEU B CD2 1 
ATOM   7658  N N   . LEU B 1 436 ? 94.900  155.648 165.939 1.00 101.39 ? 436 LEU B N   1 
ATOM   7659  C CA  . LEU B 1 436 ? 94.777  156.233 164.602 1.00 101.16 ? 436 LEU B CA  1 
ATOM   7660  C C   . LEU B 1 436 ? 95.660  155.487 163.596 1.00 105.16 ? 436 LEU B C   1 
ATOM   7661  O O   . LEU B 1 436 ? 95.183  155.107 162.534 1.00 106.75 ? 436 LEU B O   1 
ATOM   7662  C CB  . LEU B 1 436 ? 95.136  157.728 164.672 1.00 101.15 ? 436 LEU B CB  1 
ATOM   7663  C CG  . LEU B 1 436 ? 95.197  158.438 163.309 1.00 99.96  ? 436 LEU B CG  1 
ATOM   7664  C CD1 . LEU B 1 436 ? 93.837  158.462 162.621 1.00 102.06 ? 436 LEU B CD1 1 
ATOM   7665  C CD2 . LEU B 1 436 ? 95.669  159.869 163.500 1.00 98.01  ? 436 LEU B CD2 1 
ATOM   7666  N N   . GLY B 1 437 ? 96.918  155.215 163.943 1.00 97.04  ? 437 GLY B N   1 
ATOM   7667  C CA  . GLY B 1 437 ? 97.831  154.445 163.106 1.00 89.54  ? 437 GLY B CA  1 
ATOM   7668  C C   . GLY B 1 437 ? 97.288  153.060 162.753 1.00 92.60  ? 437 GLY B C   1 
ATOM   7669  O O   . GLY B 1 437 ? 97.333  152.670 161.590 1.00 102.82 ? 437 GLY B O   1 
ATOM   7670  N N   . HIS B 1 438 ? 96.703  152.336 163.706 1.00 92.79  ? 438 HIS B N   1 
ATOM   7671  C CA  . HIS B 1 438 ? 96.051  151.051 163.432 1.00 91.74  ? 438 HIS B CA  1 
ATOM   7672  C C   . HIS B 1 438 ? 94.850  151.173 162.489 1.00 97.22  ? 438 HIS B C   1 
ATOM   7673  O O   . HIS B 1 438 ? 94.688  150.336 161.604 1.00 99.10  ? 438 HIS B O   1 
ATOM   7674  C CB  . HIS B 1 438 ? 95.629  150.389 164.747 1.00 96.29  ? 438 HIS B CB  1 
ATOM   7675  C CG  . HIS B 1 438 ? 96.738  149.591 165.364 1.00 99.01  ? 438 HIS B CG  1 
ATOM   7676  N ND1 . HIS B 1 438 ? 97.191  148.378 164.909 1.00 100.22 ? 438 HIS B ND1 1 
ATOM   7677  C CD2 . HIS B 1 438 ? 97.528  149.950 166.417 1.00 97.99  ? 438 HIS B CD2 1 
ATOM   7678  C CE1 . HIS B 1 438 ? 98.221  148.002 165.681 1.00 97.76  ? 438 HIS B CE1 1 
ATOM   7679  N NE2 . HIS B 1 438 ? 98.456  148.926 166.623 1.00 98.42  ? 438 HIS B NE2 1 
ATOM   7680  N N   . ILE B 1 439 ? 94.022  152.210 162.625 1.00 102.72 ? 439 ILE B N   1 
ATOM   7681  C CA  . ILE B 1 439 ? 92.895  152.442 161.712 1.00 98.95  ? 439 ILE B CA  1 
ATOM   7682  C C   . ILE B 1 439 ? 93.386  152.819 160.308 1.00 95.88  ? 439 ILE B C   1 
ATOM   7683  O O   . ILE B 1 439 ? 92.902  152.257 159.331 1.00 98.40  ? 439 ILE B O   1 
ATOM   7684  C CB  . ILE B 1 439 ? 91.915  153.476 162.303 1.00 98.32  ? 439 ILE B CB  1 
ATOM   7685  C CG1 . ILE B 1 439 ? 91.262  152.977 163.610 1.00 99.75  ? 439 ILE B CG1 1 
ATOM   7686  C CG2 . ILE B 1 439 ? 90.824  153.863 161.299 1.00 94.53  ? 439 ILE B CG2 1 
ATOM   7687  C CD1 . ILE B 1 439 ? 90.496  151.662 163.529 1.00 95.58  ? 439 ILE B CD1 1 
ATOM   7688  N N   . LEU B 1 440 ? 94.387  153.688 160.168 1.00 84.91  ? 440 LEU B N   1 
ATOM   7689  C CA  . LEU B 1 440 ? 94.988  153.978 158.867 1.00 86.53  ? 440 LEU B CA  1 
ATOM   7690  C C   . LEU B 1 440 ? 95.604  152.735 158.212 1.00 87.07  ? 440 LEU B C   1 
ATOM   7691  O O   . LEU B 1 440 ? 95.464  152.557 157.009 1.00 93.38  ? 440 LEU B O   1 
ATOM   7692  C CB  . LEU B 1 440 ? 96.028  155.100 159.012 1.00 88.65  ? 440 LEU B CB  1 
ATOM   7693  C CG  . LEU B 1 440 ? 95.445  156.461 159.421 1.00 92.38  ? 440 LEU B CG  1 
ATOM   7694  C CD1 . LEU B 1 440 ? 96.580  157.454 159.647 1.00 89.27  ? 440 LEU B CD1 1 
ATOM   7695  C CD2 . LEU B 1 440 ? 94.519  157.034 158.357 1.00 90.98  ? 440 LEU B CD2 1 
ATOM   7696  N N   . ILE B 1 441 ? 96.228  151.834 158.973 1.00 77.31  ? 441 ILE B N   1 
ATOM   7697  C CA  . ILE B 1 441 ? 96.731  150.554 158.451 1.00 79.97  ? 441 ILE B CA  1 
ATOM   7698  C C   . ILE B 1 441 ? 95.587  149.623 158.051 1.00 85.35  ? 441 ILE B C   1 
ATOM   7699  O O   . ILE B 1 441 ? 95.678  148.990 157.006 1.00 92.07  ? 441 ILE B O   1 
ATOM   7700  C CB  . ILE B 1 441 ? 97.678  149.893 159.467 1.00 84.82  ? 441 ILE B CB  1 
ATOM   7701  C CG1 . ILE B 1 441 ? 98.985  150.697 159.520 1.00 84.98  ? 441 ILE B CG1 1 
ATOM   7702  C CG2 . ILE B 1 441 ? 98.003  148.431 159.135 1.00 85.37  ? 441 ILE B CG2 1 
ATOM   7703  C CD1 . ILE B 1 441 ? 99.778  150.411 160.787 1.00 90.96  ? 441 ILE B CD1 1 
ATOM   7704  N N   . LEU B 1 442 ? 94.495  149.549 158.814 1.00 78.79  ? 442 LEU B N   1 
ATOM   7705  C CA  . LEU B 1 442 ? 93.309  148.778 158.430 1.00 77.73  ? 442 LEU B CA  1 
ATOM   7706  C C   . LEU B 1 442 ? 92.720  149.298 157.111 1.00 82.34  ? 442 LEU B C   1 
ATOM   7707  O O   . LEU B 1 442 ? 92.480  148.518 156.198 1.00 82.72  ? 442 LEU B O   1 
ATOM   7708  C CB  . LEU B 1 442 ? 92.275  148.834 159.568 1.00 81.79  ? 442 LEU B CB  1 
ATOM   7709  C CG  . LEU B 1 442 ? 90.961  148.096 159.262 1.00 83.38  ? 442 LEU B CG  1 
ATOM   7710  C CD1 . LEU B 1 442 ? 91.148  146.590 159.215 1.00 79.60  ? 442 LEU B CD1 1 
ATOM   7711  C CD2 . LEU B 1 442 ? 89.930  148.426 160.330 1.00 80.70  ? 442 LEU B CD2 1 
ATOM   7712  N N   . LEU B 1 443 ? 92.519  150.610 156.984 1.00 88.96  ? 443 LEU B N   1 
ATOM   7713  C CA  . LEU B 1 443 ? 91.972  151.230 155.778 1.00 81.90  ? 443 LEU B CA  1 
ATOM   7714  C C   . LEU B 1 443 ? 92.908  151.104 154.573 1.00 80.39  ? 443 LEU B C   1 
ATOM   7715  O O   . LEU B 1 443 ? 92.447  150.748 153.497 1.00 87.10  ? 443 LEU B O   1 
ATOM   7716  C CB  . LEU B 1 443 ? 91.635  152.703 156.045 1.00 81.91  ? 443 LEU B CB  1 
ATOM   7717  C CG  . LEU B 1 443 ? 90.496  152.935 157.049 1.00 86.02  ? 443 LEU B CG  1 
ATOM   7718  C CD1 . LEU B 1 443 ? 90.285  154.436 157.207 1.00 84.20  ? 443 LEU B CD1 1 
ATOM   7719  C CD2 . LEU B 1 443 ? 89.176  152.304 156.611 1.00 83.01  ? 443 LEU B CD2 1 
ATOM   7720  N N   . GLY B 1 444 ? 94.217  151.309 154.731 1.00 69.94  ? 444 GLY B N   1 
ATOM   7721  C CA  . GLY B 1 444 ? 95.195  151.040 153.675 1.00 72.89  ? 444 GLY B CA  1 
ATOM   7722  C C   . GLY B 1 444 ? 95.267  149.561 153.284 1.00 73.53  ? 444 GLY B C   1 
ATOM   7723  O O   . GLY B 1 444 ? 95.404  149.240 152.109 1.00 81.71  ? 444 GLY B O   1 
ATOM   7724  N N   . GLY B 1 445 ? 95.090  148.644 154.236 1.00 71.25  ? 445 GLY B N   1 
ATOM   7725  C CA  . GLY B 1 445 ? 95.037  147.209 153.982 1.00 68.09  ? 445 GLY B CA  1 
ATOM   7726  C C   . GLY B 1 445 ? 93.765  146.772 153.268 1.00 71.66  ? 445 GLY B C   1 
ATOM   7727  O O   . GLY B 1 445 ? 93.847  146.017 152.310 1.00 82.65  ? 445 GLY B O   1 
ATOM   7728  N N   . ILE B 1 446 ? 92.595  147.300 153.634 1.00 74.69  ? 446 ILE B N   1 
ATOM   7729  C CA  . ILE B 1 446 ? 91.342  147.073 152.901 1.00 71.63  ? 446 ILE B CA  1 
ATOM   7730  C C   . ILE B 1 446 ? 91.408  147.705 151.508 1.00 78.33  ? 446 ILE B C   1 
ATOM   7731  O O   . ILE B 1 446 ? 91.041  147.053 150.539 1.00 82.97  ? 446 ILE B O   1 
ATOM   7732  C CB  . ILE B 1 446 ? 90.134  147.595 153.708 1.00 75.36  ? 446 ILE B CB  1 
ATOM   7733  C CG1 . ILE B 1 446 ? 89.901  146.699 154.941 1.00 80.31  ? 446 ILE B CG1 1 
ATOM   7734  C CG2 . ILE B 1 446 ? 88.854  147.649 152.856 1.00 74.32  ? 446 ILE B CG2 1 
ATOM   7735  C CD1 . ILE B 1 446 ? 88.895  147.275 155.943 1.00 77.39  ? 446 ILE B CD1 1 
ATOM   7736  N N   . TYR B 1 447 ? 91.913  148.932 151.367 1.00 76.24  ? 447 TYR B N   1 
ATOM   7737  C CA  . TYR B 1 447 ? 92.068  149.575 150.064 1.00 66.08  ? 447 TYR B CA  1 
ATOM   7738  C C   . TYR B 1 447 ? 92.920  148.737 149.111 1.00 71.03  ? 447 TYR B C   1 
ATOM   7739  O O   . TYR B 1 447 ? 92.499  148.464 147.992 1.00 82.24  ? 447 TYR B O   1 
ATOM   7740  C CB  . TYR B 1 447 ? 92.669  150.972 150.241 1.00 68.44  ? 447 TYR B CB  1 
ATOM   7741  C CG  . TYR B 1 447 ? 92.849  151.694 148.927 1.00 76.93  ? 447 TYR B CG  1 
ATOM   7742  C CD1 . TYR B 1 447 ? 93.989  151.456 148.138 1.00 78.63  ? 447 TYR B CD1 1 
ATOM   7743  C CD2 . TYR B 1 447 ? 91.830  152.534 148.452 1.00 76.57  ? 447 TYR B CD2 1 
ATOM   7744  C CE1 . TYR B 1 447 ? 94.086  152.002 146.846 1.00 72.39  ? 447 TYR B CE1 1 
ATOM   7745  C CE2 . TYR B 1 447 ? 91.931  153.096 147.172 1.00 79.34  ? 447 TYR B CE2 1 
ATOM   7746  C CZ  . TYR B 1 447 ? 93.042  152.808 146.354 1.00 79.94  ? 447 TYR B CZ  1 
ATOM   7747  O OH  . TYR B 1 447 ? 93.097  153.286 145.087 1.00 86.69  ? 447 TYR B OH  1 
ATOM   7748  N N   . LEU B 1 448 ? 94.101  148.288 149.547 1.00 65.29  ? 448 LEU B N   1 
ATOM   7749  C CA  . LEU B 1 448 ? 94.962  147.419 148.751 1.00 60.17  ? 448 LEU B CA  1 
ATOM   7750  C C   . LEU B 1 448 ? 94.344  146.036 148.527 1.00 65.26  ? 448 LEU B C   1 
ATOM   7751  O O   . LEU B 1 448 ? 94.484  145.505 147.430 1.00 78.23  ? 448 LEU B O   1 
ATOM   7752  C CB  . LEU B 1 448 ? 96.334  147.293 149.426 1.00 70.71  ? 448 LEU B CB  1 
ATOM   7753  C CG  . LEU B 1 448 ? 97.181  148.574 149.394 1.00 67.39  ? 448 LEU B CG  1 
ATOM   7754  C CD1 . LEU B 1 448 ? 98.374  148.407 150.322 1.00 70.87  ? 448 LEU B CD1 1 
ATOM   7755  C CD2 . LEU B 1 448 ? 97.721  148.862 147.997 1.00 70.72  ? 448 LEU B CD2 1 
ATOM   7756  N N   . LEU B 1 449 ? 93.626  145.460 149.499 1.00 68.74  ? 449 LEU B N   1 
ATOM   7757  C CA  . LEU B 1 449 ? 92.926  144.189 149.296 1.00 67.55  ? 449 LEU B CA  1 
ATOM   7758  C C   . LEU B 1 449 ? 91.867  144.331 148.208 1.00 74.26  ? 449 LEU B C   1 
ATOM   7759  O O   . LEU B 1 449 ? 91.834  143.528 147.277 1.00 75.08  ? 449 LEU B O   1 
ATOM   7760  C CB  . LEU B 1 449 ? 92.320  143.710 150.626 1.00 71.52  ? 449 LEU B CB  1 
ATOM   7761  C CG  . LEU B 1 449 ? 91.502  142.417 150.539 1.00 74.06  ? 449 LEU B CG  1 
ATOM   7762  C CD1 . LEU B 1 449 ? 92.328  141.267 149.992 1.00 74.40  ? 449 LEU B CD1 1 
ATOM   7763  C CD2 . LEU B 1 449 ? 91.016  142.025 151.925 1.00 72.98  ? 449 LEU B CD2 1 
ATOM   7764  N N   . LEU B 1 450 ? 91.038  145.381 148.213 1.00 79.71  ? 450 LEU B N   1 
ATOM   7765  C CA  . LEU B 1 450 ? 90.046  145.633 147.158 1.00 74.41  ? 450 LEU B CA  1 
ATOM   7766  C C   . LEU B 1 450 ? 90.678  145.943 145.794 1.00 74.77  ? 450 LEU B C   1 
ATOM   7767  O O   . LEU B 1 450 ? 90.236  145.411 144.782 1.00 78.02  ? 450 LEU B O   1 
ATOM   7768  C CB  . LEU B 1 450 ? 89.113  146.779 147.573 1.00 73.59  ? 450 LEU B CB  1 
ATOM   7769  C CG  . LEU B 1 450 ? 88.192  146.457 148.753 1.00 76.25  ? 450 LEU B CG  1 
ATOM   7770  C CD1 . LEU B 1 450 ? 87.351  147.685 149.076 1.00 74.01  ? 450 LEU B CD1 1 
ATOM   7771  C CD2 . LEU B 1 450 ? 87.248  145.296 148.459 1.00 72.64  ? 450 LEU B CD2 1 
ATOM   7772  N N   . GLY B 1 451 ? 91.735  146.751 145.748 1.00 77.34  ? 451 GLY B N   1 
ATOM   7773  C CA  . GLY B 1 451 ? 92.464  147.043 144.516 1.00 69.98  ? 451 GLY B CA  1 
ATOM   7774  C C   . GLY B 1 451 ? 93.076  145.806 143.854 1.00 70.93  ? 451 GLY B C   1 
ATOM   7775  O O   . GLY B 1 451 ? 92.990  145.668 142.634 1.00 78.23  ? 451 GLY B O   1 
ATOM   7776  N N   . GLN B 1 452 ? 93.643  144.867 144.618 1.00 73.99  ? 452 GLN B N   1 
ATOM   7777  C CA  . GLN B 1 452 ? 94.179  143.628 144.047 1.00 74.64  ? 452 GLN B CA  1 
ATOM   7778  C C   . GLN B 1 452 ? 93.107  142.582 143.724 1.00 71.10  ? 452 GLN B C   1 
ATOM   7779  O O   . GLN B 1 452 ? 93.242  141.869 142.734 1.00 80.57  ? 452 GLN B O   1 
ATOM   7780  C CB  . GLN B 1 452 ? 95.239  143.022 144.970 1.00 71.00  ? 452 GLN B CB  1 
ATOM   7781  C CG  . GLN B 1 452 ? 96.487  143.893 145.135 1.00 68.84  ? 452 GLN B CG  1 
ATOM   7782  C CD  . GLN B 1 452 ? 97.151  144.283 143.823 1.00 75.09  ? 452 GLN B CD  1 
ATOM   7783  O OE1 . GLN B 1 452 ? 97.256  145.449 143.485 1.00 80.89  ? 452 GLN B OE1 1 
ATOM   7784  N NE2 . GLN B 1 452 ? 97.611  143.352 143.024 1.00 71.97  ? 452 GLN B NE2 1 
ATOM   7785  N N   . LEU B 1 453 ? 92.015  142.492 144.484 1.00 68.67  ? 453 LEU B N   1 
ATOM   7786  C CA  . LEU B 1 453 ? 90.889  141.642 144.083 1.00 73.51  ? 453 LEU B CA  1 
ATOM   7787  C C   . LEU B 1 453 ? 90.232  142.158 142.794 1.00 75.71  ? 453 LEU B C   1 
ATOM   7788  O O   . LEU B 1 453 ? 89.864  141.355 141.943 1.00 80.49  ? 453 LEU B O   1 
ATOM   7789  C CB  . LEU B 1 453 ? 89.871  141.525 145.225 1.00 77.27  ? 453 LEU B CB  1 
ATOM   7790  C CG  . LEU B 1 453 ? 90.357  140.692 146.426 1.00 78.39  ? 453 LEU B CG  1 
ATOM   7791  C CD1 . LEU B 1 453 ? 89.343  140.800 147.554 1.00 71.75  ? 453 LEU B CD1 1 
ATOM   7792  C CD2 . LEU B 1 453 ? 90.511  139.217 146.085 1.00 73.75  ? 453 LEU B CD2 1 
ATOM   7793  N N   . TRP B 1 454 ? 90.157  143.474 142.579 1.00 86.82  ? 454 TRP B N   1 
ATOM   7794  C CA  . TRP B 1 454 ? 89.727  144.039 141.298 1.00 81.58  ? 454 TRP B CA  1 
ATOM   7795  C C   . TRP B 1 454 ? 90.685  143.686 140.154 1.00 81.50  ? 454 TRP B C   1 
ATOM   7796  O O   . TRP B 1 454 ? 90.221  143.281 139.096 1.00 92.75  ? 454 TRP B O   1 
ATOM   7797  C CB  . TRP B 1 454 ? 89.553  145.551 141.430 1.00 82.21  ? 454 TRP B CB  1 
ATOM   7798  C CG  . TRP B 1 454 ? 88.956  146.246 140.246 1.00 88.16  ? 454 TRP B CG  1 
ATOM   7799  C CD1 . TRP B 1 454 ? 87.746  145.973 139.711 1.00 88.62  ? 454 TRP B CD1 1 
ATOM   7800  C CD2 . TRP B 1 454 ? 89.491  147.359 139.467 1.00 92.71  ? 454 TRP B CD2 1 
ATOM   7801  N NE1 . TRP B 1 454 ? 87.496  146.834 138.663 1.00 86.52  ? 454 TRP B NE1 1 
ATOM   7802  C CE2 . TRP B 1 454 ? 88.522  147.732 138.492 1.00 89.18  ? 454 TRP B CE2 1 
ATOM   7803  C CE3 . TRP B 1 454 ? 90.687  148.109 139.498 1.00 90.47  ? 454 TRP B CE3 1 
ATOM   7804  C CZ2 . TRP B 1 454 ? 88.715  148.804 137.611 1.00 88.34  ? 454 TRP B CZ2 1 
ATOM   7805  C CZ3 . TRP B 1 454 ? 90.896  149.181 138.607 1.00 89.71  ? 454 TRP B CZ3 1 
ATOM   7806  C CH2 . TRP B 1 454 ? 89.910  149.538 137.673 1.00 91.21  ? 454 TRP B CH2 1 
ATOM   7807  N N   . TYR B 1 455 ? 92.006  143.738 140.357 1.00 75.95  ? 455 TYR B N   1 
ATOM   7808  C CA  . TYR B 1 455 ? 92.981  143.285 139.356 1.00 73.95  ? 455 TYR B CA  1 
ATOM   7809  C C   . TYR B 1 455 ? 92.752  141.832 138.941 1.00 81.50  ? 455 TYR B C   1 
ATOM   7810  O O   . TYR B 1 455 ? 92.575  141.549 137.758 1.00 90.87  ? 455 TYR B O   1 
ATOM   7811  C CB  . TYR B 1 455 ? 94.414  143.484 139.858 1.00 78.80  ? 455 TYR B CB  1 
ATOM   7812  C CG  . TYR B 1 455 ? 95.472  143.001 138.886 1.00 83.25  ? 455 TYR B CG  1 
ATOM   7813  C CD1 . TYR B 1 455 ? 95.853  143.820 137.813 1.00 83.54  ? 455 TYR B CD1 1 
ATOM   7814  C CD2 . TYR B 1 455 ? 96.056  141.730 139.028 1.00 83.11  ? 455 TYR B CD2 1 
ATOM   7815  C CE1 . TYR B 1 455 ? 96.811  143.379 136.885 1.00 82.29  ? 455 TYR B CE1 1 
ATOM   7816  C CE2 . TYR B 1 455 ? 97.007  141.276 138.096 1.00 88.26  ? 455 TYR B CE2 1 
ATOM   7817  C CZ  . TYR B 1 455 ? 97.391  142.106 137.022 1.00 89.72  ? 455 TYR B CZ  1 
ATOM   7818  O OH  . TYR B 1 455 ? 98.317  141.698 136.120 1.00 88.48  ? 455 TYR B OH  1 
ATOM   7819  N N   . PHE B 1 456 ? 92.679  140.893 139.884 1.00 84.30  ? 456 PHE B N   1 
ATOM   7820  C CA  . PHE B 1 456 ? 92.446  139.488 139.547 1.00 82.51  ? 456 PHE B CA  1 
ATOM   7821  C C   . PHE B 1 456 ? 91.033  139.202 139.037 1.00 86.95  ? 456 PHE B C   1 
ATOM   7822  O O   . PHE B 1 456 ? 90.861  138.276 138.255 1.00 93.64  ? 456 PHE B O   1 
ATOM   7823  C CB  . PHE B 1 456 ? 92.812  138.598 140.729 1.00 77.34  ? 456 PHE B CB  1 
ATOM   7824  C CG  . PHE B 1 456 ? 94.297  138.606 141.025 1.00 83.67  ? 456 PHE B CG  1 
ATOM   7825  C CD1 . PHE B 1 456 ? 95.201  138.152 140.049 1.00 85.47  ? 456 PHE B CD1 1 
ATOM   7826  C CD2 . PHE B 1 456 ? 94.778  139.089 142.250 1.00 80.73  ? 456 PHE B CD2 1 
ATOM   7827  C CE1 . PHE B 1 456 ? 96.581  138.176 140.297 1.00 85.99  ? 456 PHE B CE1 1 
ATOM   7828  C CE2 . PHE B 1 456 ? 96.158  139.114 142.499 1.00 80.57  ? 456 PHE B CE2 1 
ATOM   7829  C CZ  . PHE B 1 456 ? 97.055  138.650 141.527 1.00 85.08  ? 456 PHE B CZ  1 
ATOM   7830  N N   . TRP B 1 457 ? 90.030  140.008 139.381 1.00 88.82  ? 457 TRP B N   1 
ATOM   7831  C CA  . TRP B 1 457 ? 88.713  139.927 138.749 1.00 85.95  ? 457 TRP B CA  1 
ATOM   7832  C C   . TRP B 1 457 ? 88.750  140.358 137.279 1.00 90.31  ? 457 TRP B C   1 
ATOM   7833  O O   . TRP B 1 457 ? 88.231  139.650 136.419 1.00 92.35  ? 457 TRP B O   1 
ATOM   7834  C CB  . TRP B 1 457 ? 87.703  140.764 139.531 1.00 87.83  ? 457 TRP B CB  1 
ATOM   7835  C CG  . TRP B 1 457 ? 86.360  140.841 138.888 1.00 92.15  ? 457 TRP B CG  1 
ATOM   7836  C CD1 . TRP B 1 457 ? 85.800  141.950 138.359 1.00 91.96  ? 457 TRP B CD1 1 
ATOM   7837  C CD2 . TRP B 1 457 ? 85.408  139.762 138.655 1.00 95.33  ? 457 TRP B CD2 1 
ATOM   7838  N NE1 . TRP B 1 457 ? 84.577  141.632 137.810 1.00 94.31  ? 457 TRP B NE1 1 
ATOM   7839  C CE2 . TRP B 1 457 ? 84.290  140.292 137.953 1.00 95.48  ? 457 TRP B CE2 1 
ATOM   7840  C CE3 . TRP B 1 457 ? 85.383  138.384 138.958 1.00 93.13  ? 457 TRP B CE3 1 
ATOM   7841  C CZ2 . TRP B 1 457 ? 83.210  139.493 137.555 1.00 93.18  ? 457 TRP B CZ2 1 
ATOM   7842  C CZ3 . TRP B 1 457 ? 84.304  137.576 138.564 1.00 92.66  ? 457 TRP B CZ3 1 
ATOM   7843  C CH2 . TRP B 1 457 ? 83.222  138.124 137.859 1.00 93.28  ? 457 TRP B CH2 1 
ATOM   7844  N N   . ARG B 1 458 ? 89.449  141.459 136.977 1.00 84.24  ? 458 ARG B N   1 
ATOM   7845  C CA  . ARG B 1 458 ? 89.568  141.945 135.570 1.00 83.51  ? 458 ARG B CA  1 
ATOM   7846  C C   . ARG B 1 458 ? 90.392  140.972 134.725 1.00 87.63  ? 458 ARG B C   1 
ATOM   7847  O O   . ARG B 1 458 ? 90.046  140.782 133.544 1.00 88.55  ? 458 ARG B O   1 
ATOM   7848  C CB  . ARG B 1 458 ? 90.212  143.338 135.550 1.00 80.25  ? 458 ARG B CB  1 
ATOM   7849  C CG  . ARG B 1 458 ? 89.216  144.427 135.954 1.00 78.39  ? 458 ARG B CG  1 
ATOM   7850  C CD  . ARG B 1 458 ? 89.744  145.826 135.631 1.00 81.57  ? 458 ARG B CD  1 
ATOM   7851  N NE  . ARG B 1 458 ? 90.783  146.274 136.574 1.00 86.68  ? 458 ARG B NE  1 
ATOM   7852  C CZ  . ARG B 1 458 ? 92.078  146.002 136.458 1.00 85.29  ? 458 ARG B CZ  1 
ATOM   7853  N NH1 . ARG B 1 458 ? 92.931  146.451 137.363 1.00 83.47  ? 458 ARG B NH1 1 
ATOM   7854  N NH2 . ARG B 1 458 ? 92.516  145.281 135.441 1.00 82.90  ? 458 ARG B NH2 1 
ATOM   7855  N N   . ARG B 1 459 ? 91.430  140.385 135.304 1.00 87.39  ? 459 ARG B N   1 
ATOM   7856  C CA  . ARG B 1 459 ? 92.364  139.454 134.644 1.00 91.00  ? 459 ARG B CA  1 
ATOM   7857  C C   . ARG B 1 459 ? 91.957  137.971 134.695 1.00 97.61  ? 459 ARG B C   1 
ATOM   7858  O O   . ARG B 1 459 ? 92.703  137.115 134.233 1.00 99.31  ? 459 ARG B O   1 
ATOM   7859  C CB  . ARG B 1 459 ? 93.774  139.712 135.202 1.00 89.14  ? 459 ARG B CB  1 
ATOM   7860  C CG  . ARG B 1 459 ? 94.285  141.155 134.994 1.00 89.40  ? 459 ARG B CG  1 
ATOM   7861  C CD  . ARG B 1 459 ? 94.408  141.578 133.527 1.00 87.51  ? 459 ARG B CD  1 
ATOM   7862  N NE  . ARG B 1 459 ? 94.538  143.040 133.387 1.00 91.41  ? 459 ARG B NE  1 
ATOM   7863  C CZ  . ARG B 1 459 ? 94.083  143.780 132.391 1.00 96.08  ? 459 ARG B CZ  1 
ATOM   7864  N NH1 . ARG B 1 459 ? 94.263  145.064 132.405 1.00 89.26  ? 459 ARG B NH1 1 
ATOM   7865  N NH2 . ARG B 1 459 ? 93.436  143.275 131.381 1.00 93.80  ? 459 ARG B NH2 1 
ATOM   7866  N N   . ARG B 1 460 ? 90.755  137.697 135.236 1.00 106.31 ? 460 ARG B N   1 
ATOM   7867  C CA  . ARG B 1 460 ? 90.191  136.324 135.462 1.00 104.45 ? 460 ARG B CA  1 
ATOM   7868  C C   . ARG B 1 460 ? 90.427  135.324 134.323 1.00 105.98 ? 460 ARG B C   1 
ATOM   7869  O O   . ARG B 1 460 ? 90.868  134.199 134.629 1.00 105.26 ? 460 ARG B O   1 
ATOM   7870  C CB  . ARG B 1 460 ? 88.713  136.560 135.786 1.00 100.75 ? 460 ARG B CB  1 
ATOM   7871  C CG  . ARG B 1 460 ? 87.884  135.326 136.136 1.00 101.96 ? 460 ARG B CG  1 
ATOM   7872  C CD  . ARG B 1 460 ? 86.461  135.761 136.502 1.00 103.99 ? 460 ARG B CD  1 
ATOM   7873  N NE  . ARG B 1 460 ? 85.643  136.081 135.318 1.00 104.96 ? 460 ARG B NE  1 
ATOM   7874  C CZ  . ARG B 1 460 ? 85.462  137.308 134.843 1.00 103.30 ? 460 ARG B CZ  1 
ATOM   7875  N NH1 . ARG B 1 460 ? 84.710  137.500 133.773 1.00 101.34 ? 460 ARG B NH1 1 
ATOM   7876  N NH2 . ARG B 1 460 ? 86.028  138.340 135.444 1.00 100.69 ? 460 ARG B NH2 1 
ATOM   7877  N N   . LEU B 1 461 ? 90.159  135.696 133.077 1.00 103.82 ? 461 LEU B N   1 
ATOM   7878  C CA  . LEU B 1 461 ? 90.226  134.779 131.927 1.00 105.55 ? 461 LEU B CA  1 
ATOM   7879  C C   . LEU B 1 461 ? 91.655  134.318 131.584 1.00 105.51 ? 461 LEU B C   1 
ATOM   7880  O O   . LEU B 1 461 ? 91.831  133.272 130.960 1.00 100.63 ? 461 LEU B O   1 
ATOM   7881  C CB  . LEU B 1 461 ? 89.569  135.439 130.704 1.00 105.57 ? 461 LEU B CB  1 
ATOM   7882  C CG  . LEU B 1 461 ? 88.090  135.831 130.877 1.00 106.68 ? 461 LEU B CG  1 
ATOM   7883  C CD1 . LEU B 1 461 ? 87.561  136.410 129.572 1.00 102.12 ? 461 LEU B CD1 1 
ATOM   7884  C CD2 . LEU B 1 461 ? 87.203  134.653 131.261 1.00 106.34 ? 461 LEU B CD2 1 
ATOM   7885  N N   . PHE B 1 462 ? 92.664  135.099 131.966 1.00 105.49 ? 462 PHE B N   1 
ATOM   7886  C CA  . PHE B 1 462 ? 94.077  134.897 131.631 1.00 104.20 ? 462 PHE B CA  1 
ATOM   7887  C C   . PHE B 1 462 ? 94.932  135.076 132.890 1.00 102.01 ? 462 PHE B C   1 
ATOM   7888  O O   . PHE B 1 462 ? 95.971  135.741 132.883 1.00 102.33 ? 462 PHE B O   1 
ATOM   7889  C CB  . PHE B 1 462 ? 94.479  135.830 130.478 1.00 100.36 ? 462 PHE B CB  1 
ATOM   7890  C CG  . PHE B 1 462 ? 93.692  135.614 129.201 1.00 101.27 ? 462 PHE B CG  1 
ATOM   7891  C CD1 . PHE B 1 462 ? 94.019  134.551 128.343 1.00 99.05  ? 462 PHE B CD1 1 
ATOM   7892  C CD2 . PHE B 1 462 ? 92.591  136.434 128.901 1.00 103.01 ? 462 PHE B CD2 1 
ATOM   7893  C CE1 . PHE B 1 462 ? 93.238  134.295 127.205 1.00 100.28 ? 462 PHE B CE1 1 
ATOM   7894  C CE2 . PHE B 1 462 ? 91.806  136.177 127.766 1.00 105.40 ? 462 PHE B CE2 1 
ATOM   7895  C CZ  . PHE B 1 462 ? 92.126  135.101 126.923 1.00 102.49 ? 462 PHE B CZ  1 
ATOM   7896  N N   . ILE B 1 463 ? 94.450  134.540 134.008 1.00 106.69 ? 463 ILE B N   1 
ATOM   7897  C CA  . ILE B 1 463 ? 94.917  134.926 135.340 1.00 111.86 ? 463 ILE B CA  1 
ATOM   7898  C C   . ILE B 1 463 ? 96.388  134.556 135.569 1.00 114.75 ? 463 ILE B C   1 
ATOM   7899  O O   . ILE B 1 463 ? 97.158  135.398 136.020 1.00 112.69 ? 463 ILE B O   1 
ATOM   7900  C CB  . ILE B 1 463 ? 93.938  134.390 136.402 1.00 110.98 ? 463 ILE B CB  1 
ATOM   7901  C CG1 . ILE B 1 463 ? 94.200  135.064 137.758 1.00 110.93 ? 463 ILE B CG1 1 
ATOM   7902  C CG2 . ILE B 1 463 ? 93.964  132.860 136.525 1.00 110.68 ? 463 ILE B CG2 1 
ATOM   7903  C CD1 . ILE B 1 463 ? 93.123  134.788 138.803 1.00 109.15 ? 463 ILE B CD1 1 
ATOM   7904  N N   . TRP B 1 464 ? 96.820  133.368 135.134 1.00 113.54 ? 464 TRP B N   1 
ATOM   7905  C CA  . TRP B 1 464 ? 98.220  132.942 135.197 1.00 111.95 ? 464 TRP B CA  1 
ATOM   7906  C C   . TRP B 1 464 ? 99.139  133.804 134.328 1.00 112.02 ? 464 TRP B C   1 
ATOM   7907  O O   . TRP B 1 464 ? 100.209 134.225 134.765 1.00 112.46 ? 464 TRP B O   1 
ATOM   7908  C CB  . TRP B 1 464 ? 98.306  131.485 134.755 1.00 108.39 ? 464 TRP B CB  1 
ATOM   7909  N N   . ILE B 1 465 ? 98.703  134.162 133.118 1.00 106.82 ? 465 ILE B N   1 
ATOM   7910  C CA  . ILE B 1 465 ? 99.425  135.086 132.224 1.00 107.23 ? 465 ILE B CA  1 
ATOM   7911  C C   . ILE B 1 465 ? 99.570  136.470 132.871 1.00 104.67 ? 465 ILE B C   1 
ATOM   7912  O O   . ILE B 1 465 ? 100.586 137.141 132.739 1.00 107.47 ? 465 ILE B O   1 
ATOM   7913  C CB  . ILE B 1 465 ? 98.734  135.200 130.846 1.00 105.94 ? 465 ILE B CB  1 
ATOM   7914  C CG1 . ILE B 1 465 ? 98.412  133.812 130.256 1.00 102.54 ? 465 ILE B CG1 1 
ATOM   7915  C CG2 . ILE B 1 465 ? 99.621  136.012 129.899 1.00 100.67 ? 465 ILE B CG2 1 
ATOM   7916  C CD1 . ILE B 1 465 ? 97.781  133.862 128.867 1.00 102.05 ? 465 ILE B CD1 1 
ATOM   7917  N N   . SER B 1 466 ? 98.569  136.874 133.641 1.00 106.16 ? 466 SER B N   1 
ATOM   7918  C CA  . SER B 1 466 ? 98.547  138.149 134.351 1.00 112.64 ? 466 SER B CA  1 
ATOM   7919  C C   . SER B 1 466 ? 99.325  138.152 135.679 1.00 114.22 ? 466 SER B C   1 
ATOM   7920  O O   . SER B 1 466 ? 99.308  139.169 136.372 1.00 114.79 ? 466 SER B O   1 
ATOM   7921  C CB  . SER B 1 466 ? 97.096  138.577 134.538 1.00 111.27 ? 466 SER B CB  1 
ATOM   7922  O OG  . SER B 1 466 ? 96.457  138.596 133.274 1.00 111.10 ? 466 SER B OG  1 
ATOM   7923  N N   . PHE B 1 467 ? 100.036 137.071 136.039 1.00 115.98 ? 467 PHE B N   1 
ATOM   7924  C CA  . PHE B 1 467 ? 100.984 137.061 137.162 1.00 116.11 ? 467 PHE B CA  1 
ATOM   7925  C C   . PHE B 1 467 ? 102.321 136.338 136.904 1.00 116.59 ? 467 PHE B C   1 
ATOM   7926  O O   . PHE B 1 467 ? 103.223 136.464 137.725 1.00 117.59 ? 467 PHE B O   1 
ATOM   7927  C CB  . PHE B 1 467 ? 100.301 136.573 138.451 1.00 113.79 ? 467 PHE B CB  1 
ATOM   7928  C CG  . PHE B 1 467 ? 99.819  135.130 138.511 1.00 115.52 ? 467 PHE B CG  1 
ATOM   7929  C CD1 . PHE B 1 467 ? 100.730 134.056 138.484 1.00 114.44 ? 467 PHE B CD1 1 
ATOM   7930  C CD2 . PHE B 1 467 ? 98.455  134.858 138.730 1.00 114.61 ? 467 PHE B CD2 1 
ATOM   7931  C CE1 . PHE B 1 467 ? 100.284 132.740 138.669 1.00 115.95 ? 467 PHE B CE1 1 
ATOM   7932  C CE2 . PHE B 1 467 ? 98.011  133.542 138.931 1.00 113.31 ? 467 PHE B CE2 1 
ATOM   7933  C CZ  . PHE B 1 467 ? 98.924  132.478 138.901 1.00 114.49 ? 467 PHE B CZ  1 
ATOM   7934  N N   . MET B 1 468 ? 102.498 135.604 135.798 1.00 113.30 ? 468 MET B N   1 
ATOM   7935  C CA  . MET B 1 468 ? 103.706 134.794 135.541 1.00 113.33 ? 468 MET B CA  1 
ATOM   7936  C C   . MET B 1 468 ? 105.021 135.587 135.625 1.00 113.27 ? 468 MET B C   1 
ATOM   7937  O O   . MET B 1 468 ? 105.970 135.150 136.271 1.00 110.54 ? 468 MET B O   1 
ATOM   7938  C CB  . MET B 1 468 ? 103.593 134.065 134.186 1.00 113.12 ? 468 MET B CB  1 
ATOM   7939  C CG  . MET B 1 468 ? 103.167 134.956 133.008 1.00 112.44 ? 468 MET B CG  1 
ATOM   7940  S SD  . MET B 1 468 ? 103.194 134.222 131.346 1.00 118.64 ? 468 MET B SD  1 
ATOM   7941  C CE  . MET B 1 468 ? 102.306 132.659 131.592 1.00 110.66 ? 468 MET B CE  1 
ATOM   7942  N N   . ASP B 1 469 ? 105.065 136.775 135.020 1.00 106.55 ? 469 ASP B N   1 
ATOM   7943  C CA  . ASP B 1 469 ? 106.149 137.754 135.180 1.00 103.84 ? 469 ASP B CA  1 
ATOM   7944  C C   . ASP B 1 469 ? 105.848 138.777 136.290 1.00 102.04 ? 469 ASP B C   1 
ATOM   7945  O O   . ASP B 1 469 ? 106.750 139.263 136.964 1.00 102.81 ? 469 ASP B O   1 
ATOM   7946  C CB  . ASP B 1 469 ? 106.382 138.471 133.841 1.00 102.41 ? 469 ASP B CB  1 
ATOM   7947  C CG  . ASP B 1 469 ? 105.151 139.148 133.213 1.00 101.15 ? 469 ASP B CG  1 
ATOM   7948  O OD1 . ASP B 1 469 ? 104.074 139.222 133.848 1.00 101.33 ? 469 ASP B OD1 1 
ATOM   7949  O OD2 . ASP B 1 469 ? 105.277 139.597 132.057 1.00 101.95 ? 469 ASP B OD2 1 
ATOM   7950  N N   . SER B 1 470 ? 104.571 139.094 136.479 1.00 89.84  ? 470 SER B N   1 
ATOM   7951  C CA  . SER B 1 470 ? 104.033 140.135 137.344 1.00 86.55  ? 470 SER B CA  1 
ATOM   7952  C C   . SER B 1 470 ? 103.739 139.600 138.745 1.00 87.84  ? 470 SER B C   1 
ATOM   7953  O O   . SER B 1 470 ? 102.631 139.724 139.266 1.00 86.90  ? 470 SER B O   1 
ATOM   7954  C CB  . SER B 1 470 ? 102.804 140.749 136.669 1.00 89.15  ? 470 SER B CB  1 
ATOM   7955  O OG  . SER B 1 470 ? 103.153 141.249 135.390 1.00 96.00  ? 470 SER B OG  1 
ATOM   7956  N N   . TYR B 1 471 ? 104.743 138.992 139.375 1.00 78.52  ? 471 TYR B N   1 
ATOM   7957  C CA  . TYR B 1 471 ? 104.629 138.367 140.692 1.00 63.54  ? 471 TYR B CA  1 
ATOM   7958  C C   . TYR B 1 471 ? 104.263 139.339 141.819 1.00 61.30  ? 471 TYR B C   1 
ATOM   7959  O O   . TYR B 1 471 ? 103.629 138.932 142.789 1.00 65.75  ? 471 TYR B O   1 
ATOM   7960  C CB  . TYR B 1 471 ? 105.923 137.614 141.005 1.00 68.23  ? 471 TYR B CB  1 
ATOM   7961  C CG  . TYR B 1 471 ? 107.173 138.457 141.181 1.00 75.56  ? 471 TYR B CG  1 
ATOM   7962  C CD1 . TYR B 1 471 ? 107.493 138.977 142.449 1.00 72.53  ? 471 TYR B CD1 1 
ATOM   7963  C CD2 . TYR B 1 471 ? 108.064 138.653 140.108 1.00 73.72  ? 471 TYR B CD2 1 
ATOM   7964  C CE1 . TYR B 1 471 ? 108.714 139.645 142.658 1.00 73.74  ? 471 TYR B CE1 1 
ATOM   7965  C CE2 . TYR B 1 471 ? 109.275 139.346 140.303 1.00 72.45  ? 471 TYR B CE2 1 
ATOM   7966  C CZ  . TYR B 1 471 ? 109.613 139.820 141.585 1.00 77.60  ? 471 TYR B CZ  1 
ATOM   7967  O OH  . TYR B 1 471 ? 110.805 140.432 141.806 1.00 71.10  ? 471 TYR B OH  1 
ATOM   7968  N N   . PHE B 1 472 ? 104.562 140.633 141.696 1.00 62.58  ? 472 PHE B N   1 
ATOM   7969  C CA  . PHE B 1 472 ? 104.136 141.640 142.669 1.00 57.22  ? 472 PHE B CA  1 
ATOM   7970  C C   . PHE B 1 472 ? 102.616 141.738 142.804 1.00 62.26  ? 472 PHE B C   1 
ATOM   7971  O O   . PHE B 1 472 ? 102.135 142.076 143.875 1.00 74.38  ? 472 PHE B O   1 
ATOM   7972  C CB  . PHE B 1 472 ? 104.711 143.012 142.323 1.00 52.47  ? 472 PHE B CB  1 
ATOM   7973  C CG  . PHE B 1 472 ? 106.188 143.163 142.598 1.00 59.78  ? 472 PHE B CG  1 
ATOM   7974  C CD1 . PHE B 1 472 ? 106.629 143.382 143.910 1.00 57.98  ? 472 PHE B CD1 1 
ATOM   7975  C CD2 . PHE B 1 472 ? 107.116 143.114 141.547 1.00 62.03  ? 472 PHE B CD2 1 
ATOM   7976  C CE1 . PHE B 1 472 ? 107.998 143.543 144.173 1.00 54.08  ? 472 PHE B CE1 1 
ATOM   7977  C CE2 . PHE B 1 472 ? 108.482 143.295 141.808 1.00 61.32  ? 472 PHE B CE2 1 
ATOM   7978  C CZ  . PHE B 1 472 ? 108.922 143.509 143.120 1.00 56.01  ? 472 PHE B CZ  1 
ATOM   7979  N N   . GLU B 1 473 ? 101.822 141.402 141.792 1.00 74.94  ? 473 GLU B N   1 
ATOM   7980  C CA  . GLU B 1 473 ? 100.363 141.485 141.926 1.00 70.37  ? 473 GLU B CA  1 
ATOM   7981  C C   . GLU B 1 473 ? 99.810  140.467 142.936 1.00 75.39  ? 473 GLU B C   1 
ATOM   7982  O O   . GLU B 1 473 ? 98.790  140.726 143.574 1.00 80.03  ? 473 GLU B O   1 
ATOM   7983  C CB  . GLU B 1 473 ? 99.699  141.362 140.544 1.00 74.11  ? 473 GLU B CB  1 
ATOM   7984  C CG  . GLU B 1 473 ? 100.174 142.426 139.536 1.00 79.50  ? 473 GLU B CG  1 
ATOM   7985  C CD  . GLU B 1 473 ? 100.105 143.867 140.069 1.00 88.41  ? 473 GLU B CD  1 
ATOM   7986  O OE1 . GLU B 1 473 ? 99.174  144.219 140.829 1.00 90.00  ? 473 GLU B OE1 1 
ATOM   7987  O OE2 . GLU B 1 473 ? 101.019 144.674 139.776 1.00 86.46  ? 473 GLU B OE2 1 
ATOM   7988  N N   . ILE B 1 474 ? 100.515 139.349 143.150 1.00 69.67  ? 474 ILE B N   1 
ATOM   7989  C CA  . ILE B 1 474 ? 100.256 138.381 144.223 1.00 61.40  ? 474 ILE B CA  1 
ATOM   7990  C C   . ILE B 1 474 ? 100.795 138.890 145.563 1.00 68.67  ? 474 ILE B C   1 
ATOM   7991  O O   . ILE B 1 474 ? 100.107 138.801 146.574 1.00 71.68  ? 474 ILE B O   1 
ATOM   7992  C CB  . ILE B 1 474 ? 100.883 137.014 143.877 1.00 67.07  ? 474 ILE B CB  1 
ATOM   7993  C CG1 . ILE B 1 474 ? 100.303 136.433 142.575 1.00 68.54  ? 474 ILE B CG1 1 
ATOM   7994  C CG2 . ILE B 1 474 ? 100.684 136.020 145.031 1.00 68.27  ? 474 ILE B CG2 1 
ATOM   7995  C CD1 . ILE B 1 474 ? 101.107 135.256 142.041 1.00 67.05  ? 474 ILE B CD1 1 
ATOM   7996  N N   . LEU B 1 475 ? 102.016 139.438 145.603 1.00 63.79  ? 475 LEU B N   1 
ATOM   7997  C CA  . LEU B 1 475 ? 102.643 139.916 146.838 1.00 57.95  ? 475 LEU B CA  1 
ATOM   7998  C C   . LEU B 1 475 ? 101.944 141.134 147.451 1.00 58.64  ? 475 LEU B C   1 
ATOM   7999  O O   . LEU B 1 475 ? 101.908 141.272 148.670 1.00 75.08  ? 475 LEU B O   1 
ATOM   8000  C CB  . LEU B 1 475 ? 104.122 140.239 146.602 1.00 52.18  ? 475 LEU B CB  1 
ATOM   8001  C CG  . LEU B 1 475 ? 105.007 139.101 146.084 1.00 53.83  ? 475 LEU B CG  1 
ATOM   8002  C CD1 . LEU B 1 475 ? 106.433 139.620 145.949 1.00 61.18  ? 475 LEU B CD1 1 
ATOM   8003  C CD2 . LEU B 1 475 ? 105.018 137.898 147.017 1.00 62.21  ? 475 LEU B CD2 1 
ATOM   8004  N N   . PHE B 1 476 ? 101.337 142.006 146.651 1.00 43.86  ? 476 PHE B N   1 
ATOM   8005  C CA  . PHE B 1 476 ? 100.456 143.062 147.146 1.00 47.58  ? 476 PHE B CA  1 
ATOM   8006  C C   . PHE B 1 476 ? 99.126  142.503 147.693 1.00 55.39  ? 476 PHE B C   1 
ATOM   8007  O O   . PHE B 1 476 ? 98.551  143.107 148.592 1.00 56.75  ? 476 PHE B O   1 
ATOM   8008  C CB  . PHE B 1 476 ? 100.236 144.111 146.047 1.00 50.15  ? 476 PHE B CB  1 
ATOM   8009  C CG  . PHE B 1 476 ? 101.271 145.225 145.985 1.00 52.49  ? 476 PHE B CG  1 
ATOM   8010  C CD1 . PHE B 1 476 ? 102.499 145.048 145.329 1.00 61.16  ? 476 PHE B CD1 1 
ATOM   8011  C CD2 . PHE B 1 476 ? 100.981 146.479 146.546 1.00 57.65  ? 476 PHE B CD2 1 
ATOM   8012  C CE1 . PHE B 1 476 ? 103.411 146.107 145.216 1.00 59.08  ? 476 PHE B CE1 1 
ATOM   8013  C CE2 . PHE B 1 476 ? 101.891 147.543 146.434 1.00 54.90  ? 476 PHE B CE2 1 
ATOM   8014  C CZ  . PHE B 1 476 ? 103.103 147.357 145.765 1.00 44.60  ? 476 PHE B CZ  1 
ATOM   8015  N N   . LEU B 1 477 ? 98.599  141.412 147.130 1.00 63.51  ? 477 LEU B N   1 
ATOM   8016  C CA  . LEU B 1 477 ? 97.368  140.787 147.613 1.00 62.57  ? 477 LEU B CA  1 
ATOM   8017  C C   . LEU B 1 477 ? 97.638  140.083 148.937 1.00 68.00  ? 477 LEU B C   1 
ATOM   8018  O O   . LEU B 1 477 ? 96.890  140.246 149.893 1.00 75.20  ? 477 LEU B O   1 
ATOM   8019  C CB  . LEU B 1 477 ? 96.818  139.812 146.555 1.00 65.39  ? 477 LEU B CB  1 
ATOM   8020  C CG  . LEU B 1 477 ? 95.560  139.046 146.998 1.00 63.61  ? 477 LEU B CG  1 
ATOM   8021  C CD1 . LEU B 1 477 ? 94.361  139.966 147.158 1.00 69.22  ? 477 LEU B CD1 1 
ATOM   8022  C CD2 . LEU B 1 477 ? 95.192  137.976 145.980 1.00 67.88  ? 477 LEU B CD2 1 
ATOM   8023  N N   . LEU B 1 478 ? 98.755  139.368 149.021 1.00 68.90  ? 478 LEU B N   1 
ATOM   8024  C CA  . LEU B 1 478 ? 99.230  138.710 150.224 1.00 63.58  ? 478 LEU B CA  1 
ATOM   8025  C C   . LEU B 1 478 ? 99.520  139.716 151.346 1.00 66.04  ? 478 LEU B C   1 
ATOM   8026  O O   . LEU B 1 478 ? 99.033  139.538 152.456 1.00 73.97  ? 478 LEU B O   1 
ATOM   8027  C CB  . LEU B 1 478 ? 100.451 137.869 149.830 1.00 61.06  ? 478 LEU B CB  1 
ATOM   8028  C CG  . LEU B 1 478 ? 101.058 137.049 150.969 1.00 70.78  ? 478 LEU B CG  1 
ATOM   8029  C CD1 . LEU B 1 478 ? 100.081 136.017 151.518 1.00 67.47  ? 478 LEU B CD1 1 
ATOM   8030  C CD2 . LEU B 1 478 ? 102.300 136.335 150.450 1.00 66.46  ? 478 LEU B CD2 1 
ATOM   8031  N N   . GLN B 1 479 ? 100.235 140.813 151.083 1.00 61.27  ? 479 GLN B N   1 
ATOM   8032  C CA  . GLN B 1 479 ? 100.469 141.849 152.097 1.00 60.88  ? 479 GLN B CA  1 
ATOM   8033  C C   . GLN B 1 479 ? 99.162  142.473 152.595 1.00 65.39  ? 479 GLN B C   1 
ATOM   8034  O O   . GLN B 1 479 ? 99.002  142.693 153.794 1.00 69.90  ? 479 GLN B O   1 
ATOM   8035  C CB  . GLN B 1 479 ? 101.413 142.918 151.539 1.00 59.59  ? 479 GLN B CB  1 
ATOM   8036  C CG  . GLN B 1 479 ? 102.079 143.783 152.615 1.00 59.32  ? 479 GLN B CG  1 
ATOM   8037  C CD  . GLN B 1 479 ? 101.346 145.041 153.084 1.00 65.46  ? 479 GLN B CD  1 
ATOM   8038  O OE1 . GLN B 1 479 ? 100.330 145.464 152.565 1.00 66.75  ? 479 GLN B OE1 1 
ATOM   8039  N NE2 . GLN B 1 479 ? 101.865 145.694 154.094 1.00 70.64  ? 479 GLN B NE2 1 
ATOM   8040  N N   . ALA B 1 480 ? 98.196  142.704 151.710 1.00 76.74  ? 480 ALA B N   1 
ATOM   8041  C CA  . ALA B 1 480 ? 96.896  143.240 152.072 1.00 69.31  ? 480 ALA B CA  1 
ATOM   8042  C C   . ALA B 1 480 ? 96.051  142.239 152.876 1.00 74.78  ? 480 ALA B C   1 
ATOM   8043  O O   . ALA B 1 480 ? 95.491  142.613 153.904 1.00 78.14  ? 480 ALA B O   1 
ATOM   8044  C CB  . ALA B 1 480 ? 96.197  143.670 150.793 1.00 70.98  ? 480 ALA B CB  1 
ATOM   8045  N N   . LEU B 1 481 ? 96.010  140.958 152.490 1.00 71.76  ? 481 LEU B N   1 
ATOM   8046  C CA  . LEU B 1 481 ? 95.345  139.909 153.269 1.00 72.24  ? 481 LEU B CA  1 
ATOM   8047  C C   . LEU B 1 481 ? 95.933  139.808 154.676 1.00 76.52  ? 481 LEU B C   1 
ATOM   8048  O O   . LEU B 1 481 ? 95.189  139.838 155.649 1.00 79.03  ? 481 LEU B O   1 
ATOM   8049  C CB  . LEU B 1 481 ? 95.463  138.547 152.563 1.00 73.51  ? 481 LEU B CB  1 
ATOM   8050  C CG  . LEU B 1 481 ? 94.484  138.332 151.402 1.00 82.94  ? 481 LEU B CG  1 
ATOM   8051  C CD1 . LEU B 1 481 ? 94.838  137.045 150.666 1.00 76.30  ? 481 LEU B CD1 1 
ATOM   8052  C CD2 . LEU B 1 481 ? 93.047  138.196 151.892 1.00 77.92  ? 481 LEU B CD2 1 
ATOM   8053  N N   . LEU B 1 482 ? 97.257  139.738 154.805 1.00 76.55  ? 482 LEU B N   1 
ATOM   8054  C CA  . LEU B 1 482 ? 97.940  139.657 156.096 1.00 72.27  ? 482 LEU B CA  1 
ATOM   8055  C C   . LEU B 1 482 ? 97.791  140.935 156.933 1.00 64.27  ? 482 LEU B C   1 
ATOM   8056  O O   . LEU B 1 482 ? 97.764  140.871 158.159 1.00 72.04  ? 482 LEU B O   1 
ATOM   8057  C CB  . LEU B 1 482 ? 99.417  139.360 155.839 1.00 71.58  ? 482 LEU B CB  1 
ATOM   8058  C CG  . LEU B 1 482 ? 99.710  137.982 155.235 1.00 67.91  ? 482 LEU B CG  1 
ATOM   8059  C CD1 . LEU B 1 482 ? 101.160 137.979 154.774 1.00 70.06  ? 482 LEU B CD1 1 
ATOM   8060  C CD2 . LEU B 1 482 ? 99.529  136.871 156.261 1.00 70.13  ? 482 LEU B CD2 1 
ATOM   8061  N N   . THR B 1 483 ? 97.639  142.099 156.308 1.00 68.00  ? 483 THR B N   1 
ATOM   8062  C CA  . THR B 1 483 ? 97.306  143.341 157.013 1.00 72.39  ? 483 THR B CA  1 
ATOM   8063  C C   . THR B 1 483 ? 95.886  143.300 157.573 1.00 73.24  ? 483 THR B C   1 
ATOM   8064  O O   . THR B 1 483 ? 95.673  143.613 158.734 1.00 75.21  ? 483 THR B O   1 
ATOM   8065  C CB  . THR B 1 483 ? 97.473  144.559 156.101 1.00 80.53  ? 483 THR B CB  1 
ATOM   8066  O OG1 . THR B 1 483 ? 98.802  144.614 155.664 1.00 80.48  ? 483 THR B OG1 1 
ATOM   8067  C CG2 . THR B 1 483 ? 97.177  145.865 156.822 1.00 71.64  ? 483 THR B CG2 1 
ATOM   8068  N N   . VAL B 1 484 ? 94.897  142.853 156.799 1.00 82.75  ? 484 VAL B N   1 
ATOM   8069  C CA  . VAL B 1 484 ? 93.524  142.707 157.300 1.00 81.58  ? 484 VAL B CA  1 
ATOM   8070  C C   . VAL B 1 484 ? 93.436  141.606 158.363 1.00 83.07  ? 484 VAL B C   1 
ATOM   8071  O O   . VAL B 1 484 ? 92.894  141.844 159.437 1.00 86.93  ? 484 VAL B O   1 
ATOM   8072  C CB  . VAL B 1 484 ? 92.539  142.489 156.138 1.00 86.26  ? 484 VAL B CB  1 
ATOM   8073  C CG1 . VAL B 1 484 ? 91.115  142.244 156.631 1.00 86.75  ? 484 VAL B CG1 1 
ATOM   8074  C CG2 . VAL B 1 484 ? 92.504  143.730 155.247 1.00 82.75  ? 484 VAL B CG2 1 
ATOM   8075  N N   . LEU B 1 485 ? 94.036  140.435 158.141 1.00 80.61  ? 485 LEU B N   1 
ATOM   8076  C CA  . LEU B 1 485 ? 94.093  139.356 159.129 1.00 80.94  ? 485 LEU B CA  1 
ATOM   8077  C C   . LEU B 1 485 ? 94.762  139.799 160.431 1.00 85.82  ? 485 LEU B C   1 
ATOM   8078  O O   . LEU B 1 485 ? 94.227  139.525 161.498 1.00 86.24  ? 485 LEU B O   1 
ATOM   8079  C CB  . LEU B 1 485 ? 94.843  138.143 158.557 1.00 84.50  ? 485 LEU B CB  1 
ATOM   8080  C CG  . LEU B 1 485 ? 94.058  137.356 157.502 1.00 90.64  ? 485 LEU B CG  1 
ATOM   8081  C CD1 . LEU B 1 485 ? 94.998  136.424 156.745 1.00 88.55  ? 485 LEU B CD1 1 
ATOM   8082  C CD2 . LEU B 1 485 ? 92.971  136.508 158.156 1.00 87.71  ? 485 LEU B CD2 1 
ATOM   8083  N N   . SER B 1 486 ? 95.897  140.498 160.391 1.00 86.92  ? 486 SER B N   1 
ATOM   8084  C CA  . SER B 1 486 ? 96.558  140.952 161.620 1.00 76.72  ? 486 SER B CA  1 
ATOM   8085  C C   . SER B 1 486 ? 95.716  141.968 162.390 1.00 78.28  ? 486 SER B C   1 
ATOM   8086  O O   . SER B 1 486 ? 95.603  141.842 163.602 1.00 90.53  ? 486 SER B O   1 
ATOM   8087  C CB  . SER B 1 486 ? 97.962  141.491 161.349 1.00 76.02  ? 486 SER B CB  1 
ATOM   8088  O OG  . SER B 1 486 ? 97.960  142.499 160.374 1.00 86.59  ? 486 SER B OG  1 
ATOM   8089  N N   . GLN B 1 487 ? 95.033  142.916 161.746 1.00 83.93  ? 487 GLN B N   1 
ATOM   8090  C CA  . GLN B 1 487 ? 94.111  143.784 162.485 1.00 85.26  ? 487 GLN B CA  1 
ATOM   8091  C C   . GLN B 1 487 ? 92.891  143.013 163.026 1.00 85.82  ? 487 GLN B C   1 
ATOM   8092  O O   . GLN B 1 487 ? 92.474  143.265 164.149 1.00 88.76  ? 487 GLN B O   1 
ATOM   8093  C CB  . GLN B 1 487 ? 93.689  144.989 161.637 1.00 88.33  ? 487 GLN B CB  1 
ATOM   8094  C CG  . GLN B 1 487 ? 94.847  145.879 161.164 1.00 86.78  ? 487 GLN B CG  1 
ATOM   8095  C CD  . GLN B 1 487 ? 95.830  146.295 162.248 1.00 89.38  ? 487 GLN B CD  1 
ATOM   8096  O OE1 . GLN B 1 487 ? 95.480  146.643 163.364 1.00 91.01  ? 487 GLN B OE1 1 
ATOM   8097  N NE2 . GLN B 1 487 ? 97.107  146.287 161.959 1.00 89.29  ? 487 GLN B NE2 1 
ATOM   8098  N N   . VAL B 1 488 ? 92.366  142.015 162.307 1.00 91.75  ? 488 VAL B N   1 
ATOM   8099  C CA  . VAL B 1 488 ? 91.304  141.122 162.804 1.00 93.52  ? 488 VAL B CA  1 
ATOM   8100  C C   . VAL B 1 488 ? 91.758  140.328 164.029 1.00 96.00  ? 488 VAL B C   1 
ATOM   8101  O O   . VAL B 1 488 ? 91.066  140.332 165.043 1.00 93.73  ? 488 VAL B O   1 
ATOM   8102  C CB  . VAL B 1 488 ? 90.792  140.208 161.676 1.00 93.22  ? 488 VAL B CB  1 
ATOM   8103  C CG1 . VAL B 1 488 ? 89.948  139.033 162.166 1.00 92.26  ? 488 VAL B CG1 1 
ATOM   8104  C CG2 . VAL B 1 488 ? 89.932  141.018 160.706 1.00 90.89  ? 488 VAL B CG2 1 
ATOM   8105  N N   . LEU B 1 489 ? 92.938  139.706 164.006 1.00 93.65  ? 489 LEU B N   1 
ATOM   8106  C CA  . LEU B 1 489 ? 93.493  139.019 165.172 1.00 87.51  ? 489 LEU B CA  1 
ATOM   8107  C C   . LEU B 1 489 ? 93.772  139.983 166.335 1.00 84.41  ? 489 LEU B C   1 
ATOM   8108  O O   . LEU B 1 489 ? 93.610  139.598 167.490 1.00 88.63  ? 489 LEU B O   1 
ATOM   8109  C CB  . LEU B 1 489 ? 94.766  138.245 164.794 1.00 89.70  ? 489 LEU B CB  1 
ATOM   8110  C CG  . LEU B 1 489 ? 94.595  137.062 163.827 1.00 88.76  ? 489 LEU B CG  1 
ATOM   8111  C CD1 . LEU B 1 489 ? 95.821  136.165 163.933 1.00 89.65  ? 489 LEU B CD1 1 
ATOM   8112  C CD2 . LEU B 1 489 ? 93.377  136.194 164.110 1.00 89.80  ? 489 LEU B CD2 1 
ATOM   8113  N N   . ARG B 1 490 ? 94.138  141.240 166.068 1.00 92.32  ? 490 ARG B N   1 
ATOM   8114  C CA  . ARG B 1 490 ? 94.303  142.266 167.108 1.00 95.76  ? 490 ARG B CA  1 
ATOM   8115  C C   . ARG B 1 490 ? 92.971  142.688 167.733 1.00 98.36  ? 490 ARG B C   1 
ATOM   8116  O O   . ARG B 1 490 ? 92.907  142.847 168.946 1.00 98.32  ? 490 ARG B O   1 
ATOM   8117  C CB  . ARG B 1 490 ? 95.055  143.471 166.536 1.00 91.66  ? 490 ARG B CB  1 
ATOM   8118  C CG  . ARG B 1 490 ? 95.591  144.388 167.633 1.00 93.05  ? 490 ARG B CG  1 
ATOM   8119  C CD  . ARG B 1 490 ? 96.157  145.675 167.044 1.00 96.95  ? 490 ARG B CD  1 
ATOM   8120  N NE  . ARG B 1 490 ? 95.081  146.568 166.569 1.00 102.94 ? 490 ARG B NE  1 
ATOM   8121  C CZ  . ARG B 1 490 ? 94.410  147.451 167.288 1.00 100.46 ? 490 ARG B CZ  1 
ATOM   8122  N NH1 . ARG B 1 490 ? 93.448  148.139 166.752 1.00 97.88  ? 490 ARG B NH1 1 
ATOM   8123  N NH2 . ARG B 1 490 ? 94.666  147.662 168.544 1.00 95.76  ? 490 ARG B NH2 1 
ATOM   8124  N N   . PHE B 1 491 ? 91.890  142.805 166.961 1.00 107.25 ? 491 PHE B N   1 
ATOM   8125  C CA  . PHE B 1 491 ? 90.537  142.998 167.505 1.00 102.87 ? 491 PHE B CA  1 
ATOM   8126  C C   . PHE B 1 491 ? 90.043  141.774 168.297 1.00 105.29 ? 491 PHE B C   1 
ATOM   8127  O O   . PHE B 1 491 ? 89.388  141.934 169.324 1.00 104.73 ? 491 PHE B O   1 
ATOM   8128  C CB  . PHE B 1 491 ? 89.554  143.346 166.377 1.00 99.98  ? 491 PHE B CB  1 
ATOM   8129  N N   . MET B 1 492 ? 90.418  140.556 167.897 1.00 109.59 ? 492 MET B N   1 
ATOM   8130  C CA  . MET B 1 492 ? 90.239  139.333 168.698 1.00 108.71 ? 492 MET B CA  1 
ATOM   8131  C C   . MET B 1 492 ? 91.171  139.249 169.925 1.00 108.22 ? 492 MET B C   1 
ATOM   8132  O O   . MET B 1 492 ? 91.025  138.352 170.750 1.00 105.26 ? 492 MET B O   1 
ATOM   8133  C CB  . MET B 1 492 ? 90.455  138.096 167.810 1.00 109.49 ? 492 MET B CB  1 
ATOM   8134  C CG  . MET B 1 492 ? 89.383  137.924 166.733 1.00 110.54 ? 492 MET B CG  1 
ATOM   8135  S SD  . MET B 1 492 ? 89.802  136.707 165.453 1.00 118.38 ? 492 MET B SD  1 
ATOM   8136  C CE  . MET B 1 492 ? 90.025  135.208 166.440 1.00 108.24 ? 492 MET B CE  1 
ATOM   8137  N N   . GLU B 1 493 ? 92.141  140.153 170.049 1.00 107.86 ? 493 GLU B N   1 
ATOM   8138  C CA  . GLU B 1 493 ? 93.170  140.188 171.091 1.00 106.51 ? 493 GLU B CA  1 
ATOM   8139  C C   . GLU B 1 493 ? 94.069  138.943 171.198 1.00 107.51 ? 493 GLU B C   1 
ATOM   8140  O O   . GLU B 1 493 ? 94.762  138.778 172.200 1.00 104.24 ? 493 GLU B O   1 
ATOM   8141  C CB  . GLU B 1 493 ? 92.539  140.574 172.428 1.00 102.15 ? 493 GLU B CB  1 
ATOM   8142  N N   . THR B 1 494 ? 94.099  138.063 170.188 1.00 107.39 ? 494 THR B N   1 
ATOM   8143  C CA  . THR B 1 494 ? 95.018  136.910 170.173 1.00 105.79 ? 494 THR B CA  1 
ATOM   8144  C C   . THR B 1 494 ? 96.428  137.342 169.778 1.00 104.04 ? 494 THR B C   1 
ATOM   8145  O O   . THR B 1 494 ? 96.628  138.056 168.798 1.00 104.39 ? 494 THR B O   1 
ATOM   8146  C CB  . THR B 1 494 ? 94.513  135.748 169.305 1.00 103.90 ? 494 THR B CB  1 
ATOM   8147  O OG1 . THR B 1 494 ? 95.419  134.671 169.378 1.00 100.79 ? 494 THR B OG1 1 
ATOM   8148  C CG2 . THR B 1 494 ? 94.362  136.055 167.825 1.00 103.17 ? 494 THR B CG2 1 
ATOM   8149  N N   . GLU B 1 495 ? 97.436  136.920 170.536 1.00 105.44 ? 495 GLU B N   1 
ATOM   8150  C CA  . GLU B 1 495 ? 98.807  137.431 170.417 1.00 106.45 ? 495 GLU B CA  1 
ATOM   8151  C C   . GLU B 1 495 ? 99.503  137.039 169.104 1.00 107.61 ? 495 GLU B C   1 
ATOM   8152  O O   . GLU B 1 495 ? 100.470 137.679 168.698 1.00 109.11 ? 495 GLU B O   1 
ATOM   8153  C CB  . GLU B 1 495 ? 99.628  136.996 171.639 1.00 102.70 ? 495 GLU B CB  1 
ATOM   8154  N N   . TRP B 1 496 ? 98.963  136.055 168.381 1.00 99.76  ? 496 TRP B N   1 
ATOM   8155  C CA  . TRP B 1 496 ? 99.359  135.727 167.009 1.00 97.49  ? 496 TRP B CA  1 
ATOM   8156  C C   . TRP B 1 496 ? 99.083  136.844 165.991 1.00 99.32  ? 496 TRP B C   1 
ATOM   8157  O O   . TRP B 1 496 ? 99.528  136.739 164.850 1.00 96.98  ? 496 TRP B O   1 
ATOM   8158  C CB  . TRP B 1 496 ? 98.700  134.411 166.589 1.00 94.98  ? 496 TRP B CB  1 
ATOM   8159  C CG  . TRP B 1 496 ? 99.315  133.205 167.226 1.00 103.23 ? 496 TRP B CG  1 
ATOM   8160  C CD1 . TRP B 1 496 ? 98.839  132.543 168.301 1.00 100.44 ? 496 TRP B CD1 1 
ATOM   8161  C CD2 . TRP B 1 496 ? 100.559 132.531 166.859 1.00 109.18 ? 496 TRP B CD2 1 
ATOM   8162  N NE1 . TRP B 1 496 ? 99.703  131.520 168.635 1.00 99.22  ? 496 TRP B NE1 1 
ATOM   8163  C CE2 . TRP B 1 496 ? 100.788 131.474 167.787 1.00 103.51 ? 496 TRP B CE2 1 
ATOM   8164  C CE3 . TRP B 1 496 ? 101.510 132.698 165.831 1.00 105.22 ? 496 TRP B CE3 1 
ATOM   8165  C CZ2 . TRP B 1 496 ? 101.917 130.650 167.718 1.00 98.13  ? 496 TRP B CZ2 1 
ATOM   8166  C CZ3 . TRP B 1 496 ? 102.649 131.874 165.750 1.00 99.23  ? 496 TRP B CZ3 1 
ATOM   8167  C CH2 . TRP B 1 496 ? 102.856 130.856 166.694 1.00 97.38  ? 496 TRP B CH2 1 
ATOM   8168  N N   . TYR B 1 497 ? 98.425  137.947 166.367 1.00 94.58  ? 497 TYR B N   1 
ATOM   8169  C CA  . TYR B 1 497 ? 98.372  139.131 165.511 1.00 90.36  ? 497 TYR B CA  1 
ATOM   8170  C C   . TYR B 1 497 ? 99.766  139.696 165.226 1.00 92.98  ? 497 TYR B C   1 
ATOM   8171  O O   . TYR B 1 497 ? 100.000 140.164 164.113 1.00 100.88 ? 497 TYR B O   1 
ATOM   8172  C CB  . TYR B 1 497 ? 97.465  140.215 166.110 1.00 89.65  ? 497 TYR B CB  1 
ATOM   8173  C CG  . TYR B 1 497 ? 98.143  141.236 167.000 1.00 90.64  ? 497 TYR B CG  1 
ATOM   8174  C CD1 . TYR B 1 497 ? 98.811  142.340 166.434 1.00 85.98  ? 497 TYR B CD1 1 
ATOM   8175  C CD2 . TYR B 1 497 ? 98.109  141.083 168.394 1.00 93.44  ? 497 TYR B CD2 1 
ATOM   8176  C CE1 . TYR B 1 497 ? 99.483  143.261 167.258 1.00 88.42  ? 497 TYR B CE1 1 
ATOM   8177  C CE2 . TYR B 1 497 ? 98.761  142.009 169.220 1.00 95.63  ? 497 TYR B CE2 1 
ATOM   8178  C CZ  . TYR B 1 497 ? 99.462  143.090 168.656 1.00 97.16  ? 497 TYR B CZ  1 
ATOM   8179  O OH  . TYR B 1 497 ? 100.096 143.966 169.474 1.00 97.91  ? 497 TYR B OH  1 
ATOM   8180  N N   . LEU B 1 498 ? 100.707 139.660 166.177 1.00 77.40  ? 498 LEU B N   1 
ATOM   8181  C CA  . LEU B 1 498 ? 102.004 140.320 166.008 1.00 79.30  ? 498 LEU B CA  1 
ATOM   8182  C C   . LEU B 1 498 ? 102.897 139.664 164.942 1.00 80.36  ? 498 LEU B C   1 
ATOM   8183  O O   . LEU B 1 498 ? 103.385 140.391 164.083 1.00 84.67  ? 498 LEU B O   1 
ATOM   8184  C CB  . LEU B 1 498 ? 102.712 140.494 167.359 1.00 76.11  ? 498 LEU B CB  1 
ATOM   8185  C CG  . LEU B 1 498 ? 104.011 141.308 167.252 1.00 76.53  ? 498 LEU B CG  1 
ATOM   8186  C CD1 . LEU B 1 498 ? 103.762 142.756 166.838 1.00 74.23  ? 498 LEU B CD1 1 
ATOM   8187  C CD2 . LEU B 1 498 ? 104.730 141.320 168.591 1.00 80.25  ? 498 LEU B CD2 1 
ATOM   8188  N N   . PRO B 1 499 ? 103.090 138.334 164.894 1.00 77.12  ? 499 PRO B N   1 
ATOM   8189  C CA  . PRO B 1 499 ? 103.841 137.716 163.803 1.00 77.13  ? 499 PRO B CA  1 
ATOM   8190  C C   . PRO B 1 499 ? 103.194 137.881 162.414 1.00 79.13  ? 499 PRO B C   1 
ATOM   8191  O O   . PRO B 1 499 ? 103.911 137.899 161.420 1.00 73.14  ? 499 PRO B O   1 
ATOM   8192  C CB  . PRO B 1 499 ? 104.038 136.256 164.217 1.00 73.78  ? 499 PRO B CB  1 
ATOM   8193  C CG  . PRO B 1 499 ? 102.946 135.998 165.242 1.00 76.72  ? 499 PRO B CG  1 
ATOM   8194  C CD  . PRO B 1 499 ? 102.794 137.350 165.921 1.00 77.67  ? 499 PRO B CD  1 
ATOM   8195  N N   . LEU B 1 500 ? 101.874 138.084 162.302 1.00 80.90  ? 500 LEU B N   1 
ATOM   8196  C CA  . LEU B 1 500 ? 101.238 138.468 161.032 1.00 75.15  ? 500 LEU B CA  1 
ATOM   8197  C C   . LEU B 1 500 ? 101.479 139.939 160.680 1.00 73.29  ? 500 LEU B C   1 
ATOM   8198  O O   . LEU B 1 500 ? 101.727 140.260 159.517 1.00 84.41  ? 500 LEU B O   1 
ATOM   8199  C CB  . LEU B 1 500 ? 99.724  138.209 161.066 1.00 76.01  ? 500 LEU B CB  1 
ATOM   8200  C CG  . LEU B 1 500 ? 99.253  136.756 161.173 1.00 75.82  ? 500 LEU B CG  1 
ATOM   8201  C CD1 . LEU B 1 500 ? 97.745  136.737 160.942 1.00 81.98  ? 500 LEU B CD1 1 
ATOM   8202  C CD2 . LEU B 1 500 ? 99.873  135.842 160.124 1.00 69.27  ? 500 LEU B CD2 1 
ATOM   8203  N N   . LEU B 1 501 ? 101.428 140.845 161.659 1.00 63.90  ? 501 LEU B N   1 
ATOM   8204  C CA  . LEU B 1 501 ? 101.730 142.263 161.440 1.00 69.74  ? 501 LEU B CA  1 
ATOM   8205  C C   . LEU B 1 501 ? 103.182 142.433 160.988 1.00 71.58  ? 501 LEU B C   1 
ATOM   8206  O O   . LEU B 1 501 ? 103.475 143.145 160.040 1.00 81.07  ? 501 LEU B O   1 
ATOM   8207  C CB  . LEU B 1 501 ? 101.444 143.054 162.728 1.00 70.50  ? 501 LEU B CB  1 
ATOM   8208  C CG  . LEU B 1 501 ? 101.679 144.567 162.589 1.00 68.73  ? 501 LEU B CG  1 
ATOM   8209  C CD1 . LEU B 1 501 ? 100.590 145.211 161.741 1.00 73.45  ? 501 LEU B CD1 1 
ATOM   8210  C CD2 . LEU B 1 501 ? 101.653 145.230 163.963 1.00 72.32  ? 501 LEU B CD2 1 
ATOM   8211  N N   . VAL B 1 502 ? 104.102 141.719 161.616 1.00 70.79  ? 502 VAL B N   1 
ATOM   8212  C CA  . VAL B 1 502 ? 105.523 141.742 161.275 1.00 70.10  ? 502 VAL B CA  1 
ATOM   8213  C C   . VAL B 1 502 ? 105.810 141.083 159.921 1.00 68.54  ? 502 VAL B C   1 
ATOM   8214  O O   . VAL B 1 502 ? 106.601 141.609 159.150 1.00 75.63  ? 502 VAL B O   1 
ATOM   8215  C CB  . VAL B 1 502 ? 106.305 141.124 162.438 1.00 74.86  ? 502 VAL B CB  1 
ATOM   8216  C CG1 . VAL B 1 502 ? 107.749 140.842 162.067 1.00 72.92  ? 502 VAL B CG1 1 
ATOM   8217  C CG2 . VAL B 1 502 ? 106.306 142.113 163.611 1.00 66.06  ? 502 VAL B CG2 1 
ATOM   8218  N N   . LEU B 1 503 ? 105.137 139.994 159.546 1.00 73.77  ? 503 LEU B N   1 
ATOM   8219  C CA  . LEU B 1 503 ? 105.265 139.432 158.199 1.00 76.85  ? 503 LEU B CA  1 
ATOM   8220  C C   . LEU B 1 503 ? 104.764 140.406 157.121 1.00 72.81  ? 503 LEU B C   1 
ATOM   8221  O O   . LEU B 1 503 ? 105.425 140.607 156.105 1.00 73.91  ? 503 LEU B O   1 
ATOM   8222  C CB  . LEU B 1 503 ? 104.528 138.083 158.144 1.00 72.50  ? 503 LEU B CB  1 
ATOM   8223  C CG  . LEU B 1 503 ? 104.554 137.414 156.760 1.00 77.59  ? 503 LEU B CG  1 
ATOM   8224  C CD1 . LEU B 1 503 ? 105.970 137.105 156.277 1.00 77.23  ? 503 LEU B CD1 1 
ATOM   8225  C CD2 . LEU B 1 503 ? 103.770 136.109 156.813 1.00 76.72  ? 503 LEU B CD2 1 
ATOM   8226  N N   . SER B 1 504 ? 103.615 141.044 157.339 1.00 68.80  ? 504 SER B N   1 
ATOM   8227  C CA  . SER B 1 504 ? 103.074 142.044 156.415 1.00 63.24  ? 504 SER B CA  1 
ATOM   8228  C C   . SER B 1 504 ? 103.864 143.355 156.406 1.00 65.76  ? 504 SER B C   1 
ATOM   8229  O O   . SER B 1 504 ? 103.867 144.038 155.388 1.00 79.83  ? 504 SER B O   1 
ATOM   8230  C CB  . SER B 1 504 ? 101.590 142.275 156.669 1.00 66.12  ? 504 SER B CB  1 
ATOM   8231  O OG  . SER B 1 504 ? 101.309 142.538 158.013 1.00 73.89  ? 504 SER B OG  1 
ATOM   8232  N N   . LEU B 1 505 ? 104.628 143.676 157.449 1.00 60.10  ? 505 LEU B N   1 
ATOM   8233  C CA  . LEU B 1 505 ? 105.631 144.742 157.432 1.00 58.43  ? 505 LEU B CA  1 
ATOM   8234  C C   . LEU B 1 505 ? 106.832 144.392 156.545 1.00 58.36  ? 505 LEU B C   1 
ATOM   8235  O O   . LEU B 1 505 ? 107.251 145.225 155.752 1.00 65.37  ? 505 LEU B O   1 
ATOM   8236  C CB  . LEU B 1 505 ? 106.050 145.019 158.882 1.00 66.73  ? 505 LEU B CB  1 
ATOM   8237  C CG  . LEU B 1 505 ? 107.189 146.026 159.079 1.00 61.78  ? 505 LEU B CG  1 
ATOM   8238  C CD1 . LEU B 1 505 ? 106.737 147.455 158.832 1.00 64.97  ? 505 LEU B CD1 1 
ATOM   8239  C CD2 . LEU B 1 505 ? 107.672 145.909 160.518 1.00 61.00  ? 505 LEU B CD2 1 
ATOM   8240  N N   . VAL B 1 506 ? 107.360 143.165 156.620 1.00 65.39  ? 506 VAL B N   1 
ATOM   8241  C CA  . VAL B 1 506 ? 108.446 142.704 155.738 1.00 58.30  ? 506 VAL B CA  1 
ATOM   8242  C C   . VAL B 1 506 ? 107.989 142.714 154.290 1.00 66.68  ? 506 VAL B C   1 
ATOM   8243  O O   . VAL B 1 506 ? 108.583 143.409 153.477 1.00 71.39  ? 506 VAL B O   1 
ATOM   8244  C CB  . VAL B 1 506 ? 108.962 141.303 156.096 1.00 55.72  ? 506 VAL B CB  1 
ATOM   8245  C CG1 . VAL B 1 506 ? 109.983 140.799 155.083 1.00 62.78  ? 506 VAL B CG1 1 
ATOM   8246  C CG2 . VAL B 1 506 ? 109.647 141.298 157.448 1.00 56.67  ? 506 VAL B CG2 1 
ATOM   8247  N N   . LEU B 1 507 ? 106.899 142.011 153.963 1.00 66.50  ? 507 LEU B N   1 
ATOM   8248  C CA  . LEU B 1 507 ? 106.318 142.044 152.620 1.00 53.00  ? 507 LEU B CA  1 
ATOM   8249  C C   . LEU B 1 507 ? 106.043 143.474 152.171 1.00 53.75  ? 507 LEU B C   1 
ATOM   8250  O O   . LEU B 1 507 ? 106.301 143.809 151.028 1.00 72.93  ? 507 LEU B O   1 
ATOM   8251  C CB  . LEU B 1 507 ? 105.011 141.246 152.599 1.00 61.02  ? 507 LEU B CB  1 
ATOM   8252  C CG  . LEU B 1 507 ? 105.226 139.771 152.262 1.00 64.60  ? 507 LEU B CG  1 
ATOM   8253  C CD1 . LEU B 1 507 ? 103.984 138.983 152.646 1.00 63.46  ? 507 LEU B CD1 1 
ATOM   8254  C CD2 . LEU B 1 507 ? 105.466 139.587 150.767 1.00 60.24  ? 507 LEU B CD2 1 
ATOM   8255  N N   . GLY B 1 508 ? 105.575 144.335 153.064 1.00 43.90  ? 508 GLY B N   1 
ATOM   8256  C CA  . GLY B 1 508 ? 105.328 145.730 152.770 1.00 50.38  ? 508 GLY B CA  1 
ATOM   8257  C C   . GLY B 1 508 ? 106.542 146.462 152.216 1.00 48.00  ? 508 GLY B C   1 
ATOM   8258  O O   . GLY B 1 508 ? 106.413 147.148 151.210 1.00 62.85  ? 508 GLY B O   1 
ATOM   8259  N N   . TRP B 1 509 ? 107.719 146.291 152.813 1.00 57.66  ? 509 TRP B N   1 
ATOM   8260  C CA  . TRP B 1 509 ? 108.958 146.891 152.315 1.00 50.25  ? 509 TRP B CA  1 
ATOM   8261  C C   . TRP B 1 509 ? 109.526 146.152 151.108 1.00 52.50  ? 509 TRP B C   1 
ATOM   8262  O O   . TRP B 1 509 ? 109.998 146.797 150.187 1.00 56.92  ? 509 TRP B O   1 
ATOM   8263  C CB  . TRP B 1 509 ? 109.989 146.991 153.441 1.00 60.27  ? 509 TRP B CB  1 
ATOM   8264  C CG  . TRP B 1 509 ? 109.713 148.092 154.416 1.00 58.87  ? 509 TRP B CG  1 
ATOM   8265  C CD1 . TRP B 1 509 ? 109.150 147.952 155.632 1.00 51.25  ? 509 TRP B CD1 1 
ATOM   8266  C CD2 . TRP B 1 509 ? 109.925 149.526 154.244 1.00 66.24  ? 509 TRP B CD2 1 
ATOM   8267  N NE1 . TRP B 1 509 ? 108.949 149.194 156.192 1.00 55.67  ? 509 TRP B NE1 1 
ATOM   8268  C CE2 . TRP B 1 509 ? 109.374 150.201 155.368 1.00 65.99  ? 509 TRP B CE2 1 
ATOM   8269  C CE3 . TRP B 1 509 ? 110.510 150.335 153.250 1.00 65.03  ? 509 TRP B CE3 1 
ATOM   8270  C CZ2 . TRP B 1 509 ? 109.342 151.598 155.475 1.00 62.51  ? 509 TRP B CZ2 1 
ATOM   8271  C CZ3 . TRP B 1 509 ? 110.489 151.743 153.350 1.00 69.21  ? 509 TRP B CZ3 1 
ATOM   8272  C CH2 . TRP B 1 509 ? 109.892 152.378 154.450 1.00 64.60  ? 509 TRP B CH2 1 
ATOM   8273  N N   . LEU B 1 510 ? 109.433 144.825 151.031 1.00 65.02  ? 510 LEU B N   1 
ATOM   8274  C CA  . LEU B 1 510 ? 109.832 144.083 149.828 1.00 60.58  ? 510 LEU B CA  1 
ATOM   8275  C C   . LEU B 1 510 ? 109.015 144.511 148.605 1.00 62.65  ? 510 LEU B C   1 
ATOM   8276  O O   . LEU B 1 510 ? 109.566 144.735 147.535 1.00 71.09  ? 510 LEU B O   1 
ATOM   8277  C CB  . LEU B 1 510 ? 109.703 142.569 150.060 1.00 57.51  ? 510 LEU B CB  1 
ATOM   8278  C CG  . LEU B 1 510 ? 110.598 141.990 151.163 1.00 61.49  ? 510 LEU B CG  1 
ATOM   8279  C CD1 . LEU B 1 510 ? 110.385 140.486 151.248 1.00 56.78  ? 510 LEU B CD1 1 
ATOM   8280  C CD2 . LEU B 1 510 ? 112.065 142.257 150.912 1.00 57.27  ? 510 LEU B CD2 1 
ATOM   8281  N N   . ASN B 1 511 ? 107.713 144.724 148.767 1.00 58.81  ? 511 ASN B N   1 
ATOM   8282  C CA  . ASN B 1 511 ? 106.823 145.260 147.746 1.00 50.23  ? 511 ASN B CA  1 
ATOM   8283  C C   . ASN B 1 511 ? 107.209 146.664 147.289 1.00 49.70  ? 511 ASN B C   1 
ATOM   8284  O O   . ASN B 1 511 ? 106.864 147.046 146.184 1.00 61.09  ? 511 ASN B O   1 
ATOM   8285  C CB  . ASN B 1 511 ? 105.397 145.276 148.296 1.00 47.42  ? 511 ASN B CB  1 
ATOM   8286  C CG  . ASN B 1 511 ? 104.748 143.921 148.369 1.00 55.68  ? 511 ASN B CG  1 
ATOM   8287  O OD1 . ASN B 1 511 ? 105.275 142.926 147.912 1.00 61.27  ? 511 ASN B OD1 1 
ATOM   8288  N ND2 . ASN B 1 511 ? 103.562 143.843 148.916 1.00 54.25  ? 511 ASN B ND2 1 
ATOM   8289  N N   . LEU B 1 512 ? 107.962 147.430 148.074 1.00 57.24  ? 512 LEU B N   1 
ATOM   8290  C CA  . LEU B 1 512 ? 108.461 148.745 147.677 1.00 54.61  ? 512 LEU B CA  1 
ATOM   8291  C C   . LEU B 1 512 ? 109.438 148.643 146.501 1.00 49.26  ? 512 LEU B C   1 
ATOM   8292  O O   . LEU B 1 512 ? 109.587 149.584 145.732 1.00 51.47  ? 512 LEU B O   1 
ATOM   8293  C CB  . LEU B 1 512 ? 109.131 149.397 148.894 1.00 54.57  ? 512 LEU B CB  1 
ATOM   8294  C CG  . LEU B 1 512 ? 109.259 150.916 148.811 1.00 55.95  ? 512 LEU B CG  1 
ATOM   8295  C CD1 . LEU B 1 512 ? 107.894 151.583 148.912 1.00 59.62  ? 512 LEU B CD1 1 
ATOM   8296  C CD2 . LEU B 1 512 ? 110.085 151.413 149.978 1.00 57.00  ? 512 LEU B CD2 1 
ATOM   8297  N N   . LEU B 1 513 ? 110.050 147.479 146.285 1.00 49.64  ? 513 LEU B N   1 
ATOM   8298  C CA  . LEU B 1 513 ? 110.890 147.224 145.120 1.00 53.10  ? 513 LEU B CA  1 
ATOM   8299  C C   . LEU B 1 513 ? 110.099 147.146 143.820 1.00 51.95  ? 513 LEU B C   1 
ATOM   8300  O O   . LEU B 1 513 ? 110.711 147.261 142.759 1.00 57.43  ? 513 LEU B O   1 
ATOM   8301  C CB  . LEU B 1 513 ? 111.709 145.943 145.317 1.00 55.32  ? 513 LEU B CB  1 
ATOM   8302  C CG  . LEU B 1 513 ? 112.685 146.029 146.487 1.00 49.68  ? 513 LEU B CG  1 
ATOM   8303  C CD1 . LEU B 1 513 ? 113.187 144.641 146.834 1.00 49.03  ? 513 LEU B CD1 1 
ATOM   8304  C CD2 . LEU B 1 513 ? 113.868 146.931 146.162 1.00 42.30  ? 513 LEU B CD2 1 
ATOM   8305  N N   . TYR B 1 514 ? 108.766 147.046 143.824 1.00 56.24  ? 514 TYR B N   1 
ATOM   8306  C CA  . TYR B 1 514 ? 107.977 147.150 142.594 1.00 41.60  ? 514 TYR B CA  1 
ATOM   8307  C C   . TYR B 1 514 ? 108.307 148.438 141.841 1.00 50.20  ? 514 TYR B C   1 
ATOM   8308  O O   . TYR B 1 514 ? 108.608 148.410 140.650 1.00 67.15  ? 514 TYR B O   1 
ATOM   8309  C CB  . TYR B 1 514 ? 106.483 147.078 142.919 1.00 43.06  ? 514 TYR B CB  1 
ATOM   8310  C CG  . TYR B 1 514 ? 105.581 147.446 141.759 1.00 37.37  ? 514 TYR B CG  1 
ATOM   8311  C CD1 . TYR B 1 514 ? 105.304 146.519 140.746 1.00 51.27  ? 514 TYR B CD1 1 
ATOM   8312  C CD2 . TYR B 1 514 ? 105.047 148.739 141.675 1.00 59.11  ? 514 TYR B CD2 1 
ATOM   8313  C CE1 . TYR B 1 514 ? 104.514 146.894 139.646 1.00 65.13  ? 514 TYR B CE1 1 
ATOM   8314  C CE2 . TYR B 1 514 ? 104.274 149.131 140.572 1.00 56.16  ? 514 TYR B CE2 1 
ATOM   8315  C CZ  . TYR B 1 514 ? 104.009 148.206 139.546 1.00 66.79  ? 514 TYR B CZ  1 
ATOM   8316  O OH  . TYR B 1 514 ? 103.271 148.572 138.469 1.00 67.85  ? 514 TYR B OH  1 
ATOM   8317  N N   . TYR B 1 515 ? 108.338 149.564 142.551 1.00 56.41  ? 515 TYR B N   1 
ATOM   8318  C CA  . TYR B 1 515 ? 108.458 150.896 141.965 1.00 46.15  ? 515 TYR B CA  1 
ATOM   8319  C C   . TYR B 1 515 ? 109.848 151.219 141.420 1.00 43.90  ? 515 TYR B C   1 
ATOM   8320  O O   . TYR B 1 515 ? 110.027 152.246 140.777 1.00 55.09  ? 515 TYR B O   1 
ATOM   8321  C CB  . TYR B 1 515 ? 107.989 151.931 142.984 1.00 42.25  ? 515 TYR B CB  1 
ATOM   8322  C CG  . TYR B 1 515 ? 106.565 151.711 143.445 1.00 46.11  ? 515 TYR B CG  1 
ATOM   8323  C CD1 . TYR B 1 515 ? 105.496 152.174 142.659 1.00 55.54  ? 515 TYR B CD1 1 
ATOM   8324  C CD2 . TYR B 1 515 ? 106.305 151.035 144.650 1.00 48.88  ? 515 TYR B CD2 1 
ATOM   8325  C CE1 . TYR B 1 515 ? 104.172 151.974 143.078 1.00 54.03  ? 515 TYR B CE1 1 
ATOM   8326  C CE2 . TYR B 1 515 ? 104.985 150.845 145.077 1.00 46.58  ? 515 TYR B CE2 1 
ATOM   8327  C CZ  . TYR B 1 515 ? 103.916 151.313 144.293 1.00 55.69  ? 515 TYR B CZ  1 
ATOM   8328  O OH  . TYR B 1 515 ? 102.646 151.125 144.717 1.00 65.29  ? 515 TYR B OH  1 
ATOM   8329  N N   . THR B 1 516 ? 110.834 150.334 141.574 1.00 53.88  ? 516 THR B N   1 
ATOM   8330  C CA  . THR B 1 516 ? 112.157 150.504 140.947 1.00 44.85  ? 516 THR B CA  1 
ATOM   8331  C C   . THR B 1 516 ? 112.086 150.571 139.421 1.00 57.44  ? 516 THR B C   1 
ATOM   8332  O O   . THR B 1 516 ? 112.977 151.156 138.815 1.00 65.38  ? 516 THR B O   1 
ATOM   8333  C CB  . THR B 1 516 ? 113.146 149.407 141.347 1.00 57.15  ? 516 THR B CB  1 
ATOM   8334  O OG1 . THR B 1 516 ? 112.670 148.127 141.017 1.00 68.73  ? 516 THR B OG1 1 
ATOM   8335  C CG2 . THR B 1 516 ? 113.502 149.438 142.820 1.00 52.56  ? 516 THR B CG2 1 
ATOM   8336  N N   . ARG B 1 517 ? 111.022 150.053 138.792 1.00 64.92  ? 517 ARG B N   1 
ATOM   8337  C CA  . ARG B 1 517 ? 110.753 150.132 137.343 1.00 59.58  ? 517 ARG B CA  1 
ATOM   8338  C C   . ARG B 1 517 ? 110.420 151.524 136.817 1.00 62.85  ? 517 ARG B C   1 
ATOM   8339  O O   . ARG B 1 517 ? 110.366 151.699 135.606 1.00 69.45  ? 517 ARG B O   1 
ATOM   8340  C CB  . ARG B 1 517 ? 109.665 149.122 136.947 1.00 54.02  ? 517 ARG B CB  1 
ATOM   8341  C CG  . ARG B 1 517 ? 108.255 149.503 137.427 1.00 48.83  ? 517 ARG B CG  1 
ATOM   8342  C CD  . ARG B 1 517 ? 107.258 148.358 137.275 1.00 49.93  ? 517 ARG B CD  1 
ATOM   8343  N NE  . ARG B 1 517 ? 107.663 147.207 138.097 1.00 57.68  ? 517 ARG B NE  1 
ATOM   8344  C CZ  . ARG B 1 517 ? 107.385 145.941 137.882 1.00 60.14  ? 517 ARG B CZ  1 
ATOM   8345  N NH1 . ARG B 1 517 ? 107.990 145.020 138.560 1.00 53.59  ? 517 ARG B NH1 1 
ATOM   8346  N NH2 . ARG B 1 517 ? 106.521 145.565 136.990 1.00 62.20  ? 517 ARG B NH2 1 
ATOM   8347  N N   . GLY B 1 518 ? 110.198 152.513 137.676 1.00 67.57  ? 518 GLY B N   1 
ATOM   8348  C CA  . GLY B 1 518 ? 109.861 153.866 137.240 1.00 64.26  ? 518 GLY B CA  1 
ATOM   8349  C C   . GLY B 1 518 ? 111.017 154.622 136.593 1.00 69.59  ? 518 GLY B C   1 
ATOM   8350  O O   . GLY B 1 518 ? 110.782 155.520 135.793 1.00 75.00  ? 518 GLY B O   1 
ATOM   8351  N N   . PHE B 1 519 ? 112.262 154.250 136.888 1.00 64.80  ? 519 PHE B N   1 
ATOM   8352  C CA  . PHE B 1 519 ? 113.466 154.838 136.303 1.00 70.20  ? 519 PHE B CA  1 
ATOM   8353  C C   . PHE B 1 519 ? 114.240 153.795 135.517 1.00 73.44  ? 519 PHE B C   1 
ATOM   8354  O O   . PHE B 1 519 ? 114.313 152.643 135.931 1.00 73.56  ? 519 PHE B O   1 
ATOM   8355  C CB  . PHE B 1 519 ? 114.364 155.433 137.392 1.00 75.42  ? 519 PHE B CB  1 
ATOM   8356  C CG  . PHE B 1 519 ? 113.706 156.457 138.287 1.00 78.05  ? 519 PHE B CG  1 
ATOM   8357  C CD1 . PHE B 1 519 ? 113.454 157.751 137.800 1.00 73.08  ? 519 PHE B CD1 1 
ATOM   8358  C CD2 . PHE B 1 519 ? 113.349 156.124 139.604 1.00 73.34  ? 519 PHE B CD2 1 
ATOM   8359  C CE1 . PHE B 1 519 ? 112.845 158.708 138.624 1.00 69.27  ? 519 PHE B CE1 1 
ATOM   8360  C CE2 . PHE B 1 519 ? 112.743 157.084 140.430 1.00 75.92  ? 519 PHE B CE2 1 
ATOM   8361  C CZ  . PHE B 1 519 ? 112.491 158.374 139.940 1.00 70.39  ? 519 PHE B CZ  1 
ATOM   8362  N N   . GLN B 1 520 ? 114.872 154.195 134.417 1.00 83.46  ? 520 GLN B N   1 
ATOM   8363  C CA  . GLN B 1 520 ? 115.641 153.280 133.580 1.00 80.69  ? 520 GLN B CA  1 
ATOM   8364  C C   . GLN B 1 520 ? 116.755 152.573 134.350 1.00 77.12  ? 520 GLN B C   1 
ATOM   8365  O O   . GLN B 1 520 ? 116.893 151.364 134.244 1.00 74.90  ? 520 GLN B O   1 
ATOM   8366  C CB  . GLN B 1 520 ? 116.192 154.039 132.366 1.00 80.75  ? 520 GLN B CB  1 
ATOM   8367  C CG  . GLN B 1 520 ? 116.906 153.082 131.400 1.00 81.23  ? 520 GLN B CG  1 
ATOM   8368  C CD  . GLN B 1 520 ? 117.143 153.644 130.003 1.00 85.42  ? 520 GLN B CD  1 
ATOM   8369  O OE1 . GLN B 1 520 ? 116.551 154.618 129.565 1.00 86.40  ? 520 GLN B OE1 1 
ATOM   8370  N NE2 . GLN B 1 520 ? 118.021 153.040 129.236 1.00 83.35  ? 520 GLN B NE2 1 
ATOM   8371  N N   . HIS B 1 521 ? 117.540 153.288 135.154 1.00 85.96  ? 521 HIS B N   1 
ATOM   8372  C CA  . HIS B 1 521 ? 118.723 152.704 135.785 1.00 88.21  ? 521 HIS B CA  1 
ATOM   8373  C C   . HIS B 1 521 ? 118.383 151.666 136.841 1.00 90.82  ? 521 HIS B C   1 
ATOM   8374  O O   . HIS B 1 521 ? 118.853 150.538 136.732 1.00 91.83  ? 521 HIS B O   1 
ATOM   8375  C CB  . HIS B 1 521 ? 119.668 153.807 136.268 1.00 86.83  ? 521 HIS B CB  1 
ATOM   8376  C CG  . HIS B 1 521 ? 120.317 154.456 135.074 1.00 94.75  ? 521 HIS B CG  1 
ATOM   8377  N ND1 . HIS B 1 521 ? 121.313 153.865 134.296 1.00 89.69  ? 521 HIS B ND1 1 
ATOM   8378  C CD2 . HIS B 1 521 ? 119.908 155.607 134.470 1.00 94.10  ? 521 HIS B CD2 1 
ATOM   8379  C CE1 . HIS B 1 521 ? 121.490 154.681 133.246 1.00 90.45  ? 521 HIS B CE1 1 
ATOM   8380  N NE2 . HIS B 1 521 ? 120.665 155.735 133.328 1.00 91.76  ? 521 HIS B NE2 1 
ATOM   8381  N N   . THR B 1 522 ? 117.528 151.969 137.814 1.00 82.26  ? 522 THR B N   1 
ATOM   8382  C CA  . THR B 1 522 ? 117.044 150.966 138.777 1.00 73.99  ? 522 THR B CA  1 
ATOM   8383  C C   . THR B 1 522 ? 116.139 149.913 138.127 1.00 82.26  ? 522 THR B C   1 
ATOM   8384  O O   . THR B 1 522 ? 116.208 148.746 138.504 1.00 71.79  ? 522 THR B O   1 
ATOM   8385  C CB  . THR B 1 522 ? 116.310 151.634 139.946 1.00 65.54  ? 522 THR B CB  1 
ATOM   8386  O OG1 . THR B 1 522 ? 115.289 152.491 139.500 1.00 76.86  ? 522 THR B OG1 1 
ATOM   8387  C CG2 . THR B 1 522 ? 117.256 152.476 140.789 1.00 64.34  ? 522 THR B CG2 1 
ATOM   8388  N N   . GLY B 1 523 ? 115.333 150.291 137.130 1.00 83.56  ? 523 GLY B N   1 
ATOM   8389  C CA  . GLY B 1 523 ? 114.324 149.439 136.496 1.00 68.09  ? 523 GLY B CA  1 
ATOM   8390  C C   . GLY B 1 523 ? 114.885 148.400 135.540 1.00 73.13  ? 523 GLY B C   1 
ATOM   8391  O O   . GLY B 1 523 ? 114.379 147.288 135.484 1.00 76.54  ? 523 GLY B O   1 
ATOM   8392  N N   . ILE B 1 524 ? 115.975 148.717 134.847 1.00 79.24  ? 524 ILE B N   1 
ATOM   8393  C CA  . ILE B 1 524 ? 116.768 147.741 134.100 1.00 80.83  ? 524 ILE B CA  1 
ATOM   8394  C C   . ILE B 1 524 ? 117.568 146.837 135.044 1.00 85.77  ? 524 ILE B C   1 
ATOM   8395  O O   . ILE B 1 524 ? 117.668 145.644 134.785 1.00 82.02  ? 524 ILE B O   1 
ATOM   8396  C CB  . ILE B 1 524 ? 117.661 148.473 133.078 1.00 83.52  ? 524 ILE B CB  1 
ATOM   8397  C CG1 . ILE B 1 524 ? 116.753 148.941 131.925 1.00 77.39  ? 524 ILE B CG1 1 
ATOM   8398  C CG2 . ILE B 1 524 ? 118.804 147.597 132.571 1.00 84.18  ? 524 ILE B CG2 1 
ATOM   8399  C CD1 . ILE B 1 524 ? 117.480 149.689 130.814 1.00 78.40  ? 524 ILE B CD1 1 
ATOM   8400  N N   . TYR B 1 525 ? 118.097 147.336 136.164 1.00 83.84  ? 525 TYR B N   1 
ATOM   8401  C CA  . TYR B 1 525 ? 118.840 146.474 137.078 1.00 83.40  ? 525 TYR B CA  1 
ATOM   8402  C C   . TYR B 1 525 ? 117.948 145.447 137.778 1.00 82.40  ? 525 TYR B C   1 
ATOM   8403  O O   . TYR B 1 525 ? 118.299 144.273 137.836 1.00 81.65  ? 525 TYR B O   1 
ATOM   8404  C CB  . TYR B 1 525 ? 119.628 147.298 138.085 1.00 83.87  ? 525 TYR B CB  1 
ATOM   8405  C CG  . TYR B 1 525 ? 120.679 146.467 138.783 1.00 81.03  ? 525 TYR B CG  1 
ATOM   8406  C CD1 . TYR B 1 525 ? 121.786 146.008 138.050 1.00 79.24  ? 525 TYR B CD1 1 
ATOM   8407  C CD2 . TYR B 1 525 ? 120.516 146.093 140.129 1.00 80.51  ? 525 TYR B CD2 1 
ATOM   8408  C CE1 . TYR B 1 525 ? 122.735 145.169 138.658 1.00 83.94  ? 525 TYR B CE1 1 
ATOM   8409  C CE2 . TYR B 1 525 ? 121.475 145.268 140.744 1.00 83.04  ? 525 TYR B CE2 1 
ATOM   8410  C CZ  . TYR B 1 525 ? 122.585 144.804 140.007 1.00 82.24  ? 525 TYR B CZ  1 
ATOM   8411  O OH  . TYR B 1 525 ? 123.503 143.995 140.584 1.00 74.13  ? 525 TYR B OH  1 
ATOM   8412  N N   . SER B 1 526 ? 116.743 145.836 138.198 1.00 81.33  ? 526 SER B N   1 
ATOM   8413  C CA  . SER B 1 526 ? 115.728 144.893 138.682 1.00 82.45  ? 526 SER B CA  1 
ATOM   8414  C C   . SER B 1 526 ? 115.392 143.778 137.684 1.00 81.27  ? 526 SER B C   1 
ATOM   8415  O O   . SER B 1 526 ? 114.911 142.724 138.080 1.00 83.05  ? 526 SER B O   1 
ATOM   8416  C CB  . SER B 1 526 ? 114.454 145.649 139.062 1.00 85.48  ? 526 SER B CB  1 
ATOM   8417  O OG  . SER B 1 526 ? 114.716 146.475 140.177 1.00 82.43  ? 526 SER B OG  1 
ATOM   8418  N N   . VAL B 1 527 ? 115.683 143.975 136.397 1.00 88.33  ? 527 VAL B N   1 
ATOM   8419  C CA  . VAL B 1 527 ? 115.547 142.988 135.321 1.00 87.86  ? 527 VAL B CA  1 
ATOM   8420  C C   . VAL B 1 527 ? 116.847 142.218 135.044 1.00 90.09  ? 527 VAL B C   1 
ATOM   8421  O O   . VAL B 1 527 ? 116.794 141.040 134.705 1.00 89.88  ? 527 VAL B O   1 
ATOM   8422  C CB  . VAL B 1 527 ? 115.039 143.717 134.075 1.00 85.09  ? 527 VAL B CB  1 
ATOM   8423  C CG1 . VAL B 1 527 ? 115.075 142.860 132.827 1.00 86.41  ? 527 VAL B CG1 1 
ATOM   8424  C CG2 . VAL B 1 527 ? 113.592 144.164 134.260 1.00 85.01  ? 527 VAL B CG2 1 
ATOM   8425  N N   . MET B 1 528 ? 118.021 142.833 135.208 1.00 97.92  ? 528 MET B N   1 
ATOM   8426  C CA  . MET B 1 528 ? 119.315 142.139 135.115 1.00 97.18  ? 528 MET B CA  1 
ATOM   8427  C C   . MET B 1 528 ? 119.480 141.064 136.190 1.00 94.61  ? 528 MET B C   1 
ATOM   8428  O O   . MET B 1 528 ? 119.966 139.977 135.888 1.00 92.84  ? 528 MET B O   1 
ATOM   8429  C CB  . MET B 1 528 ? 120.476 143.126 135.265 1.00 96.35  ? 528 MET B CB  1 
ATOM   8430  C CG  . MET B 1 528 ? 120.663 144.047 134.061 1.00 99.60  ? 528 MET B CG  1 
ATOM   8431  S SD  . MET B 1 528 ? 121.900 145.351 134.306 1.00 108.41 ? 528 MET B SD  1 
ATOM   8432  C CE  . MET B 1 528 ? 123.375 144.360 134.640 1.00 94.89  ? 528 MET B CE  1 
ATOM   8433  N N   . ILE B 1 529 ? 119.088 141.405 137.416 1.00 95.56  ? 529 ILE B N   1 
ATOM   8434  C CA  . ILE B 1 529 ? 119.328 140.605 138.605 1.00 92.51  ? 529 ILE B CA  1 
ATOM   8435  C C   . ILE B 1 529 ? 118.401 139.378 138.675 1.00 92.75  ? 529 ILE B C   1 
ATOM   8436  O O   . ILE B 1 529 ? 118.899 138.261 138.773 1.00 91.37  ? 529 ILE B O   1 
ATOM   8437  C CB  . ILE B 1 529 ? 119.334 141.554 139.831 1.00 91.99  ? 529 ILE B CB  1 
ATOM   8438  C CG1 . ILE B 1 529 ? 120.090 140.944 141.022 1.00 90.78  ? 529 ILE B CG1 1 
ATOM   8439  C CG2 . ILE B 1 529 ? 117.939 142.021 140.270 1.00 90.26  ? 529 ILE B CG2 1 
ATOM   8440  C CD1 . ILE B 1 529 ? 120.664 141.985 141.977 1.00 89.15  ? 529 ILE B CD1 1 
ATOM   8441  N N   . GLN B 1 530 ? 117.075 139.530 138.587 1.00 97.92  ? 530 GLN B N   1 
ATOM   8442  C CA  . GLN B 1 530 ? 116.140 138.398 138.695 1.00 96.49  ? 530 GLN B CA  1 
ATOM   8443  C C   . GLN B 1 530 ? 116.135 137.550 137.415 1.00 94.61  ? 530 GLN B C   1 
ATOM   8444  O O   . GLN B 1 530 ? 115.920 138.085 136.331 1.00 94.03  ? 530 GLN B O   1 
ATOM   8445  C CB  . GLN B 1 530 ? 114.742 138.893 139.114 1.00 93.24  ? 530 GLN B CB  1 
ATOM   8446  C CG  . GLN B 1 530 ? 113.936 139.606 138.017 1.00 94.46  ? 530 GLN B CG  1 
ATOM   8447  C CD  . GLN B 1 530 ? 112.737 140.409 138.530 1.00 98.38  ? 530 GLN B CD  1 
ATOM   8448  O OE1 . GLN B 1 530 ? 112.508 140.596 139.720 1.00 99.03  ? 530 GLN B OE1 1 
ATOM   8449  N NE2 . GLN B 1 530 ? 111.882 140.874 137.652 1.00 97.52  ? 530 GLN B NE2 1 
ATOM   8450  N N   . LYS B 1 531 ? 116.396 136.236 137.515 1.00 91.25  ? 531 LYS B N   1 
ATOM   8451  C CA  . LYS B 1 531 ? 116.571 135.349 136.344 1.00 95.79  ? 531 LYS B CA  1 
ATOM   8452  C C   . LYS B 1 531 ? 116.384 133.850 136.640 1.00 99.98  ? 531 LYS B C   1 
ATOM   8453  O O   . LYS B 1 531 ? 115.887 133.474 137.701 1.00 92.48  ? 531 LYS B O   1 
ATOM   8454  C CB  . LYS B 1 531 ? 117.923 135.684 135.665 1.00 90.62  ? 531 LYS B CB  1 
ATOM   8455  C CG  . LYS B 1 531 ? 119.200 135.337 136.451 1.00 84.08  ? 531 LYS B CG  1 
ATOM   8456  C CD  . LYS B 1 531 ? 120.400 136.186 135.993 1.00 88.92  ? 531 LYS B CD  1 
ATOM   8457  C CE  . LYS B 1 531 ? 120.648 136.093 134.477 1.00 90.70  ? 531 LYS B CE  1 
ATOM   8458  N NZ  . LYS B 1 531 ? 121.625 137.102 133.997 1.00 83.80  ? 531 LYS B NZ  1 
ATOM   8459  N N   . VAL B 1 532 ? 116.838 133.006 135.702 1.00 108.16 ? 532 VAL B N   1 
ATOM   8460  C CA  . VAL B 1 532 ? 116.874 131.516 135.685 1.00 99.51  ? 532 VAL B CA  1 
ATOM   8461  C C   . VAL B 1 532 ? 117.408 130.870 136.975 1.00 95.06  ? 532 VAL B C   1 
ATOM   8462  O O   . VAL B 1 532 ? 117.092 129.723 137.278 1.00 96.47  ? 532 VAL B O   1 
ATOM   8463  C CB  . VAL B 1 532 ? 117.721 131.070 134.468 1.00 97.06  ? 532 VAL B CB  1 
ATOM   8464  C CG1 . VAL B 1 532 ? 118.121 129.597 134.461 1.00 93.95  ? 532 VAL B CG1 1 
ATOM   8465  C CG2 . VAL B 1 532 ? 116.963 131.341 133.161 1.00 96.78  ? 532 VAL B CG2 1 
ATOM   8466  N N   . ILE B 1 533 ? 118.140 131.615 137.795 1.00 90.50  ? 533 ILE B N   1 
ATOM   8467  C CA  . ILE B 1 533 ? 118.561 131.205 139.138 1.00 88.90  ? 533 ILE B CA  1 
ATOM   8468  C C   . ILE B 1 533 ? 117.365 130.768 140.005 1.00 90.60  ? 533 ILE B C   1 
ATOM   8469  O O   . ILE B 1 533 ? 117.478 129.788 140.734 1.00 93.35  ? 533 ILE B O   1 
ATOM   8470  C CB  . ILE B 1 533 ? 119.386 132.354 139.757 1.00 89.22  ? 533 ILE B CB  1 
ATOM   8471  C CG1 . ILE B 1 533 ? 120.698 132.520 138.958 1.00 92.45  ? 533 ILE B CG1 1 
ATOM   8472  C CG2 . ILE B 1 533 ? 119.697 132.114 141.240 1.00 90.34  ? 533 ILE B CG2 1 
ATOM   8473  C CD1 . ILE B 1 533 ? 121.412 133.845 139.199 1.00 92.90  ? 533 ILE B CD1 1 
ATOM   8474  N N   . LEU B 1 534 ? 116.186 131.394 139.880 1.00 92.52  ? 534 LEU B N   1 
ATOM   8475  C CA  . LEU B 1 534 ? 114.993 130.989 140.639 1.00 85.01  ? 534 LEU B CA  1 
ATOM   8476  C C   . LEU B 1 534 ? 114.464 129.596 140.260 1.00 84.45  ? 534 LEU B C   1 
ATOM   8477  O O   . LEU B 1 534 ? 113.902 128.902 141.106 1.00 84.27  ? 534 LEU B O   1 
ATOM   8478  C CB  . LEU B 1 534 ? 113.876 132.037 140.466 1.00 90.88  ? 534 LEU B CB  1 
ATOM   8479  C CG  . LEU B 1 534 ? 114.186 133.437 141.026 1.00 93.01  ? 534 LEU B CG  1 
ATOM   8480  C CD1 . LEU B 1 534 ? 113.025 134.375 140.715 1.00 86.83  ? 534 LEU B CD1 1 
ATOM   8481  C CD2 . LEU B 1 534 ? 114.399 133.435 142.536 1.00 88.11  ? 534 LEU B CD2 1 
ATOM   8482  N N   . ARG B 1 535 ? 114.745 129.168 139.013 1.00 95.69  ? 535 ARG B N   1 
ATOM   8483  C CA  . ARG B 1 535 ? 114.315 127.837 138.484 1.00 96.73  ? 535 ARG B CA  1 
ATOM   8484  C C   . ARG B 1 535 ? 115.232 126.732 138.996 1.00 94.38  ? 535 ARG B C   1 
ATOM   8485  O O   . ARG B 1 535 ? 114.713 125.679 139.414 1.00 91.59  ? 535 ARG B O   1 
ATOM   8486  C CB  . ARG B 1 535 ? 114.417 127.841 136.943 1.00 96.33  ? 535 ARG B CB  1 
ATOM   8487  C CG  . ARG B 1 535 ? 113.996 126.531 136.254 1.00 91.80  ? 535 ARG B CG  1 
ATOM   8488  C CD  . ARG B 1 535 ? 114.500 126.480 134.800 1.00 93.45  ? 535 ARG B CD  1 
ATOM   8489  N NE  . ARG B 1 535 ? 115.957 126.260 134.746 1.00 96.57  ? 535 ARG B NE  1 
ATOM   8490  C CZ  . ARG B 1 535 ? 116.680 126.218 133.633 1.00 96.76  ? 535 ARG B CZ  1 
ATOM   8491  N NH1 . ARG B 1 535 ? 117.984 126.013 133.700 1.00 92.71  ? 535 ARG B NH1 1 
ATOM   8492  N NH2 . ARG B 1 535 ? 116.098 126.385 132.458 1.00 93.94  ? 535 ARG B NH2 1 
ATOM   8493  N N   . ASP B 1 536 ? 116.540 126.968 138.964 1.00 92.54  ? 536 ASP B N   1 
ATOM   8494  C CA  . ASP B 1 536 ? 117.536 125.960 139.327 1.00 86.00  ? 536 ASP B CA  1 
ATOM   8495  C C   . ASP B 1 536 ? 117.830 125.869 140.818 1.00 86.46  ? 536 ASP B C   1 
ATOM   8496  O O   . ASP B 1 536 ? 118.072 124.773 141.312 1.00 93.57  ? 536 ASP B O   1 
ATOM   8497  C CB  . ASP B 1 536 ? 118.821 126.195 138.538 1.00 89.61  ? 536 ASP B CB  1 
ATOM   8498  C CG  . ASP B 1 536 ? 118.656 125.856 137.057 1.00 94.75  ? 536 ASP B CG  1 
ATOM   8499  O OD1 . ASP B 1 536 ? 117.652 125.208 136.680 1.00 97.83  ? 536 ASP B OD1 1 
ATOM   8500  O OD2 . ASP B 1 536 ? 119.521 126.227 136.243 1.00 94.88  ? 536 ASP B OD2 1 
ATOM   8501  N N   . LEU B 1 537 ? 117.730 126.954 141.585 1.00 85.98  ? 537 LEU B N   1 
ATOM   8502  C CA  . LEU B 1 537 ? 117.839 126.844 143.040 1.00 86.17  ? 537 LEU B CA  1 
ATOM   8503  C C   . LEU B 1 537 ? 116.727 125.988 143.649 1.00 86.73  ? 537 LEU B C   1 
ATOM   8504  O O   . LEU B 1 537 ? 116.991 125.220 144.564 1.00 91.76  ? 537 LEU B O   1 
ATOM   8505  C CB  . LEU B 1 537 ? 117.873 128.227 143.691 1.00 88.25  ? 537 LEU B CB  1 
ATOM   8506  C CG  . LEU B 1 537 ? 119.185 128.993 143.474 1.00 90.83  ? 537 LEU B CG  1 
ATOM   8507  C CD1 . LEU B 1 537 ? 119.081 130.282 144.269 1.00 87.14  ? 537 LEU B CD1 1 
ATOM   8508  C CD2 . LEU B 1 537 ? 120.418 128.241 143.972 1.00 88.73  ? 537 LEU B CD2 1 
ATOM   8509  N N   . LEU B 1 538 ? 115.513 126.021 143.103 1.00 83.58  ? 538 LEU B N   1 
ATOM   8510  C CA  . LEU B 1 538 ? 114.423 125.134 143.510 1.00 88.19  ? 538 LEU B CA  1 
ATOM   8511  C C   . LEU B 1 538 ? 114.688 123.655 143.159 1.00 84.60  ? 538 LEU B C   1 
ATOM   8512  O O   . LEU B 1 538 ? 114.095 122.759 143.754 1.00 84.06  ? 538 LEU B O   1 
ATOM   8513  C CB  . LEU B 1 538 ? 113.123 125.683 142.891 1.00 89.66  ? 538 LEU B CB  1 
ATOM   8514  C CG  . LEU B 1 538 ? 111.829 124.975 143.313 1.00 89.64  ? 538 LEU B CG  1 
ATOM   8515  C CD1 . LEU B 1 538 ? 111.596 125.052 144.818 1.00 84.51  ? 538 LEU B CD1 1 
ATOM   8516  C CD2 . LEU B 1 538 ? 110.638 125.628 142.621 1.00 87.53  ? 538 LEU B CD2 1 
ATOM   8517  N N   . ARG B 1 539 ? 115.649 123.407 142.248 1.00 79.33  ? 539 ARG B N   1 
ATOM   8518  C CA  . ARG B 1 539 ? 116.059 122.006 141.902 1.00 76.40  ? 539 ARG B CA  1 
ATOM   8519  C C   . ARG B 1 539 ? 117.199 121.603 142.852 1.00 79.54  ? 539 ARG B C   1 
ATOM   8520  O O   . ARG B 1 539 ? 117.135 120.480 143.390 1.00 84.10  ? 539 ARG B O   1 
ATOM   8521  C CB  . ARG B 1 539 ? 116.351 121.875 140.399 1.00 78.41  ? 539 ARG B CB  1 
ATOM   8522  C CG  . ARG B 1 539 ? 115.120 122.225 139.551 1.00 75.92  ? 539 ARG B CG  1 
ATOM   8523  C CD  . ARG B 1 539 ? 115.208 121.695 138.124 1.00 76.05  ? 539 ARG B CD  1 
ATOM   8524  N NE  . ARG B 1 539 ? 116.088 122.466 137.222 1.00 79.62  ? 539 ARG B NE  1 
ATOM   8525  C CZ  . ARG B 1 539 ? 116.368 122.128 135.969 1.00 78.59  ? 539 ARG B CZ  1 
ATOM   8526  N NH1 . ARG B 1 539 ? 117.171 122.888 135.243 1.00 76.30  ? 539 ARG B NH1 1 
ATOM   8527  N NH2 . ARG B 1 539 ? 115.849 121.032 135.445 1.00 79.19  ? 539 ARG B NH2 1 
ATOM   8528  N N   . PHE B 1 540 ? 118.188 122.474 143.060 1.00 81.83  ? 540 PHE B N   1 
ATOM   8529  C CA  . PHE B 1 540 ? 119.289 122.273 144.011 1.00 74.26  ? 540 PHE B CA  1 
ATOM   8530  C C   . PHE B 1 540 ? 118.784 122.078 145.439 1.00 76.00  ? 540 PHE B C   1 
ATOM   8531  O O   . PHE B 1 540 ? 119.325 121.250 146.159 1.00 74.84  ? 540 PHE B O   1 
ATOM   8532  C CB  . PHE B 1 540 ? 120.254 123.469 143.929 1.00 76.38  ? 540 PHE B CB  1 
ATOM   8533  C CG  . PHE B 1 540 ? 120.978 123.845 145.213 1.00 91.80  ? 540 PHE B CG  1 
ATOM   8534  C CD1 . PHE B 1 540 ? 122.106 123.120 145.642 1.00 85.68  ? 540 PHE B CD1 1 
ATOM   8535  C CD2 . PHE B 1 540 ? 120.520 124.936 145.981 1.00 87.27  ? 540 PHE B CD2 1 
ATOM   8536  C CE1 . PHE B 1 540 ? 122.756 123.478 146.841 1.00 78.52  ? 540 PHE B CE1 1 
ATOM   8537  C CE2 . PHE B 1 540 ? 121.160 125.283 147.176 1.00 79.01  ? 540 PHE B CE2 1 
ATOM   8538  C CZ  . PHE B 1 540 ? 122.282 124.543 147.606 1.00 80.15  ? 540 PHE B CZ  1 
ATOM   8539  N N   . LEU B 1 541 ? 117.716 122.771 145.827 1.00 74.81  ? 541 LEU B N   1 
ATOM   8540  C CA  . LEU B 1 541 ? 117.126 122.682 147.156 1.00 72.57  ? 541 LEU B CA  1 
ATOM   8541  C C   . LEU B 1 541 ? 116.662 121.257 147.492 1.00 67.71  ? 541 LEU B C   1 
ATOM   8542  O O   . LEU B 1 541 ? 116.810 120.829 148.625 1.00 75.75  ? 541 LEU B O   1 
ATOM   8543  C CB  . LEU B 1 541 ? 115.994 123.710 147.250 1.00 71.75  ? 541 LEU B CB  1 
ATOM   8544  C CG  . LEU B 1 541 ? 115.364 123.832 148.639 1.00 75.82  ? 541 LEU B CG  1 
ATOM   8545  C CD1 . LEU B 1 541 ? 116.347 124.418 149.648 1.00 72.14  ? 541 LEU B CD1 1 
ATOM   8546  C CD2 . LEU B 1 541 ? 114.140 124.731 148.565 1.00 76.85  ? 541 LEU B CD2 1 
ATOM   8547  N N   . LEU B 1 542 ? 116.177 120.479 146.524 1.00 56.79  ? 542 LEU B N   1 
ATOM   8548  C CA  . LEU B 1 542 ? 115.849 119.070 146.746 1.00 60.41  ? 542 LEU B CA  1 
ATOM   8549  C C   . LEU B 1 542 ? 117.092 118.241 147.100 1.00 61.80  ? 542 LEU B C   1 
ATOM   8550  O O   . LEU B 1 542 ? 117.068 117.457 148.043 1.00 64.97  ? 542 LEU B O   1 
ATOM   8551  C CB  . LEU B 1 542 ? 115.129 118.542 145.491 1.00 71.20  ? 542 LEU B CB  1 
ATOM   8552  C CG  . LEU B 1 542 ? 114.705 117.067 145.558 1.00 73.14  ? 542 LEU B CG  1 
ATOM   8553  C CD1 . LEU B 1 542 ? 113.690 116.794 146.666 1.00 67.64  ? 542 LEU B CD1 1 
ATOM   8554  C CD2 . LEU B 1 542 ? 114.069 116.676 144.234 1.00 60.03  ? 542 LEU B CD2 1 
ATOM   8555  N N   . VAL B 1 543 ? 118.205 118.446 146.393 1.00 66.63  ? 543 VAL B N   1 
ATOM   8556  C CA  . VAL B 1 543 ? 119.478 117.760 146.670 1.00 67.55  ? 543 VAL B CA  1 
ATOM   8557  C C   . VAL B 1 543 ? 120.058 118.199 148.015 1.00 62.46  ? 543 VAL B C   1 
ATOM   8558  O O   . VAL B 1 543 ? 120.419 117.364 148.837 1.00 59.96  ? 543 VAL B O   1 
ATOM   8559  C CB  . VAL B 1 543 ? 120.506 117.974 145.545 1.00 63.58  ? 543 VAL B CB  1 
ATOM   8560  C CG1 . VAL B 1 543 ? 121.698 117.036 145.712 1.00 55.67  ? 543 VAL B CG1 1 
ATOM   8561  C CG2 . VAL B 1 543 ? 119.911 117.706 144.162 1.00 61.64  ? 543 VAL B CG2 1 
ATOM   8562  N N   . TYR B 1 544 ? 120.073 119.506 148.286 1.00 68.60  ? 544 TYR B N   1 
ATOM   8563  C CA  . TYR B 1 544 ? 120.543 120.067 149.542 1.00 61.87  ? 544 TYR B CA  1 
ATOM   8564  C C   . TYR B 1 544 ? 119.715 119.621 150.753 1.00 61.11  ? 544 TYR B C   1 
ATOM   8565  O O   . TYR B 1 544 ? 120.291 119.324 151.793 1.00 65.28  ? 544 TYR B O   1 
ATOM   8566  C CB  . TYR B 1 544 ? 120.533 121.598 149.480 1.00 69.45  ? 544 TYR B CB  1 
ATOM   8567  C CG  . TYR B 1 544 ? 120.984 122.260 150.757 1.00 76.72  ? 544 TYR B CG  1 
ATOM   8568  C CD1 . TYR B 1 544 ? 120.085 122.540 151.774 1.00 75.45  ? 544 TYR B CD1 1 
ATOM   8569  C CD2 . TYR B 1 544 ? 122.314 122.589 150.961 1.00 72.08  ? 544 TYR B CD2 1 
ATOM   8570  C CE1 . TYR B 1 544 ? 120.493 123.141 152.953 1.00 74.41  ? 544 TYR B CE1 1 
ATOM   8571  C CE2 . TYR B 1 544 ? 122.738 123.189 152.135 1.00 66.53  ? 544 TYR B CE2 1 
ATOM   8572  C CZ  . TYR B 1 544 ? 121.825 123.467 153.135 1.00 75.48  ? 544 TYR B CZ  1 
ATOM   8573  O OH  . TYR B 1 544 ? 122.236 124.058 154.294 1.00 78.59  ? 544 TYR B OH  1 
ATOM   8574  N N   . LEU B 1 545 ? 118.387 119.521 150.649 1.00 60.97  ? 545 LEU B N   1 
ATOM   8575  C CA  . LEU B 1 545 ? 117.531 119.055 151.746 1.00 58.63  ? 545 LEU B CA  1 
ATOM   8576  C C   . LEU B 1 545 ? 117.575 117.540 151.974 1.00 54.60  ? 545 LEU B C   1 
ATOM   8577  O O   . LEU B 1 545 ? 117.421 117.114 153.113 1.00 55.11  ? 545 LEU B O   1 
ATOM   8578  C CB  . LEU B 1 545 ? 116.085 119.516 151.527 1.00 56.50  ? 545 LEU B CB  1 
ATOM   8579  C CG  . LEU B 1 545 ? 115.861 121.028 151.669 1.00 65.75  ? 545 LEU B CG  1 
ATOM   8580  C CD1 . LEU B 1 545 ? 114.397 121.328 151.387 1.00 63.24  ? 545 LEU B CD1 1 
ATOM   8581  C CD2 . LEU B 1 545 ? 116.196 121.554 153.058 1.00 66.35  ? 545 LEU B CD2 1 
ATOM   8582  N N   . VAL B 1 546 ? 117.827 116.707 150.963 1.00 65.29  ? 546 VAL B N   1 
ATOM   8583  C CA  . VAL B 1 546 ? 118.088 115.275 151.199 1.00 61.16  ? 546 VAL B CA  1 
ATOM   8584  C C   . VAL B 1 546 ? 119.432 115.071 151.892 1.00 68.30  ? 546 VAL B C   1 
ATOM   8585  O O   . VAL B 1 546 ? 119.513 114.263 152.814 1.00 65.70  ? 546 VAL B O   1 
ATOM   8586  C CB  . VAL B 1 546 ? 117.987 114.449 149.907 1.00 61.18  ? 546 VAL B CB  1 
ATOM   8587  C CG1 . VAL B 1 546 ? 118.433 113.004 150.125 1.00 57.53  ? 546 VAL B CG1 1 
ATOM   8588  C CG2 . VAL B 1 546 ? 116.538 114.400 149.419 1.00 65.16  ? 546 VAL B CG2 1 
ATOM   8589  N N   . PHE B 1 547 ? 120.472 115.832 151.533 1.00 77.33  ? 547 PHE B N   1 
ATOM   8590  C CA  . PHE B 1 547 ? 121.719 115.852 152.297 1.00 66.38  ? 547 PHE B CA  1 
ATOM   8591  C C   . PHE B 1 547 ? 121.463 116.328 153.728 1.00 68.87  ? 547 PHE B C   1 
ATOM   8592  O O   . PHE B 1 547 ? 121.762 115.610 154.676 1.00 77.65  ? 547 PHE B O   1 
ATOM   8593  C CB  . PHE B 1 547 ? 122.762 116.766 151.637 1.00 68.07  ? 547 PHE B CB  1 
ATOM   8594  C CG  . PHE B 1 547 ? 123.475 116.290 150.385 1.00 74.86  ? 547 PHE B CG  1 
ATOM   8595  C CD1 . PHE B 1 547 ? 123.075 115.154 149.660 1.00 71.03  ? 547 PHE B CD1 1 
ATOM   8596  C CD2 . PHE B 1 547 ? 124.596 117.021 149.950 1.00 75.46  ? 547 PHE B CD2 1 
ATOM   8597  C CE1 . PHE B 1 547 ? 123.807 114.736 148.538 1.00 73.22  ? 547 PHE B CE1 1 
ATOM   8598  C CE2 . PHE B 1 547 ? 125.312 116.611 148.817 1.00 77.28  ? 547 PHE B CE2 1 
ATOM   8599  C CZ  . PHE B 1 547 ? 124.927 115.467 148.112 1.00 70.36  ? 547 PHE B CZ  1 
ATOM   8600  N N   . LEU B 1 548 ? 120.881 117.511 153.907 1.00 62.91  ? 548 LEU B N   1 
ATOM   8601  C CA  . LEU B 1 548 ? 120.701 118.125 155.217 1.00 60.98  ? 548 LEU B CA  1 
ATOM   8602  C C   . LEU B 1 548 ? 119.867 117.257 156.163 1.00 64.14  ? 548 LEU B C   1 
ATOM   8603  O O   . LEU B 1 548 ? 120.305 116.993 157.275 1.00 72.05  ? 548 LEU B O   1 
ATOM   8604  C CB  . LEU B 1 548 ? 120.113 119.533 155.023 1.00 65.40  ? 548 LEU B CB  1 
ATOM   8605  C CG  . LEU B 1 548 ? 119.903 120.315 156.324 1.00 58.48  ? 548 LEU B CG  1 
ATOM   8606  C CD1 . LEU B 1 548 ? 121.224 120.596 157.012 1.00 64.99  ? 548 LEU B CD1 1 
ATOM   8607  C CD2 . LEU B 1 548 ? 119.237 121.647 156.030 1.00 61.73  ? 548 LEU B CD2 1 
ATOM   8608  N N   . PHE B 1 549 ? 118.703 116.760 155.744 1.00 67.92  ? 549 PHE B N   1 
ATOM   8609  C CA  . PHE B 1 549 ? 117.908 115.867 156.585 1.00 63.42  ? 549 PHE B CA  1 
ATOM   8610  C C   . PHE B 1 549 ? 118.593 114.510 156.796 1.00 67.26  ? 549 PHE B C   1 
ATOM   8611  O O   . PHE B 1 549 ? 118.629 114.026 157.921 1.00 63.99  ? 549 PHE B O   1 
ATOM   8612  C CB  . PHE B 1 549 ? 116.511 115.700 155.984 1.00 67.57  ? 549 PHE B CB  1 
ATOM   8613  C CG  . PHE B 1 549 ? 115.601 114.810 156.804 1.00 76.26  ? 549 PHE B CG  1 
ATOM   8614  C CD1 . PHE B 1 549 ? 114.993 115.317 157.967 1.00 78.84  ? 549 PHE B CD1 1 
ATOM   8615  C CD2 . PHE B 1 549 ? 115.365 113.474 156.427 1.00 69.40  ? 549 PHE B CD2 1 
ATOM   8616  C CE1 . PHE B 1 549 ? 114.153 114.499 158.742 1.00 71.76  ? 549 PHE B CE1 1 
ATOM   8617  C CE2 . PHE B 1 549 ? 114.527 112.660 157.205 1.00 70.30  ? 549 PHE B CE2 1 
ATOM   8618  C CZ  . PHE B 1 549 ? 113.921 113.169 158.361 1.00 70.00  ? 549 PHE B CZ  1 
ATOM   8619  N N   . GLY B 1 550 ? 119.191 113.916 155.760 1.00 72.70  ? 550 GLY B N   1 
ATOM   8620  C CA  . GLY B 1 550 ? 119.861 112.620 155.857 1.00 69.55  ? 550 GLY B CA  1 
ATOM   8621  C C   . GLY B 1 550 ? 121.005 112.604 156.869 1.00 74.92  ? 550 GLY B C   1 
ATOM   8622  O O   . GLY B 1 550 ? 121.124 111.655 157.642 1.00 74.15  ? 550 GLY B O   1 
ATOM   8623  N N   . PHE B 1 551 ? 121.813 113.667 156.912 1.00 63.50  ? 551 PHE B N   1 
ATOM   8624  C CA  . PHE B 1 551 ? 122.862 113.847 157.913 1.00 55.31  ? 551 PHE B CA  1 
ATOM   8625  C C   . PHE B 1 551 ? 122.322 114.319 159.274 1.00 68.14  ? 551 PHE B C   1 
ATOM   8626  O O   . PHE B 1 551 ? 122.868 113.915 160.297 1.00 72.43  ? 551 PHE B O   1 
ATOM   8627  C CB  . PHE B 1 551 ? 123.932 114.791 157.365 1.00 57.80  ? 551 PHE B CB  1 
ATOM   8628  C CG  . PHE B 1 551 ? 124.935 114.126 156.440 1.00 58.10  ? 551 PHE B CG  1 
ATOM   8629  C CD1 . PHE B 1 551 ? 126.043 113.467 156.995 1.00 65.17  ? 551 PHE B CD1 1 
ATOM   8630  C CD2 . PHE B 1 551 ? 124.806 114.193 155.041 1.00 58.78  ? 551 PHE B CD2 1 
ATOM   8631  C CE1 . PHE B 1 551 ? 127.000 112.867 156.165 1.00 66.71  ? 551 PHE B CE1 1 
ATOM   8632  C CE2 . PHE B 1 551 ? 125.772 113.606 154.210 1.00 59.33  ? 551 PHE B CE2 1 
ATOM   8633  C CZ  . PHE B 1 551 ? 126.864 112.934 154.771 1.00 62.94  ? 551 PHE B CZ  1 
ATOM   8634  N N   . ALA B 1 552 ? 121.243 115.106 159.351 1.00 65.89  ? 552 ALA B N   1 
ATOM   8635  C CA  . ALA B 1 552 ? 120.666 115.545 160.621 1.00 58.06  ? 552 ALA B CA  1 
ATOM   8636  C C   . ALA B 1 552 ? 120.099 114.388 161.452 1.00 63.76  ? 552 ALA B C   1 
ATOM   8637  O O   . ALA B 1 552 ? 120.436 114.264 162.627 1.00 67.33  ? 552 ALA B O   1 
ATOM   8638  C CB  . ALA B 1 552 ? 119.592 116.602 160.368 1.00 64.12  ? 552 ALA B CB  1 
ATOM   8639  N N   . VAL B 1 553 ? 119.294 113.491 160.873 1.00 73.55  ? 553 VAL B N   1 
ATOM   8640  C CA  . VAL B 1 553 ? 118.785 112.315 161.607 1.00 67.76  ? 553 VAL B CA  1 
ATOM   8641  C C   . VAL B 1 553 ? 119.918 111.397 162.076 1.00 70.82  ? 553 VAL B C   1 
ATOM   8642  O O   . VAL B 1 553 ? 119.783 110.694 163.073 1.00 72.52  ? 553 VAL B O   1 
ATOM   8643  C CB  . VAL B 1 553 ? 117.760 111.500 160.794 1.00 65.11  ? 553 VAL B CB  1 
ATOM   8644  C CG1 . VAL B 1 553 ? 116.494 112.306 160.529 1.00 66.18  ? 553 VAL B CG1 1 
ATOM   8645  C CG2 . VAL B 1 553 ? 118.270 110.970 159.453 1.00 67.05  ? 553 VAL B CG2 1 
ATOM   8646  N N   . ALA B 1 554 ? 121.056 111.413 161.391 1.00 69.96  ? 554 ALA B N   1 
ATOM   8647  C CA  . ALA B 1 554 ? 122.217 110.596 161.686 1.00 64.91  ? 554 ALA B CA  1 
ATOM   8648  C C   . ALA B 1 554 ? 123.061 111.155 162.828 1.00 72.00  ? 554 ALA B C   1 
ATOM   8649  O O   . ALA B 1 554 ? 123.349 110.442 163.783 1.00 76.31  ? 554 ALA B O   1 
ATOM   8650  C CB  . ALA B 1 554 ? 123.007 110.489 160.394 1.00 63.47  ? 554 ALA B CB  1 
ATOM   8651  N N   . LEU B 1 555 ? 123.413 112.439 162.780 1.00 80.52  ? 555 LEU B N   1 
ATOM   8652  C CA  . LEU B 1 555 ? 124.150 113.096 163.860 1.00 75.29  ? 555 LEU B CA  1 
ATOM   8653  C C   . LEU B 1 555 ? 123.348 113.113 165.158 1.00 74.63  ? 555 LEU B C   1 
ATOM   8654  O O   . LEU B 1 555 ? 123.935 112.890 166.211 1.00 77.83  ? 555 LEU B O   1 
ATOM   8655  C CB  . LEU B 1 555 ? 124.536 114.514 163.431 1.00 73.49  ? 555 LEU B CB  1 
ATOM   8656  C CG  . LEU B 1 555 ? 125.687 114.508 162.418 1.00 77.37  ? 555 LEU B CG  1 
ATOM   8657  C CD1 . LEU B 1 555 ? 125.711 115.819 161.667 1.00 80.50  ? 555 LEU B CD1 1 
ATOM   8658  C CD2 . LEU B 1 555 ? 127.038 114.352 163.104 1.00 76.97  ? 555 LEU B CD2 1 
ATOM   8659  N N   . VAL B 1 556 ? 122.027 113.289 165.104 1.00 73.70  ? 556 VAL B N   1 
ATOM   8660  C CA  . VAL B 1 556 ? 121.148 113.170 166.280 1.00 69.11  ? 556 VAL B CA  1 
ATOM   8661  C C   . VAL B 1 556 ? 121.156 111.761 166.868 1.00 78.11  ? 556 VAL B C   1 
ATOM   8662  O O   . VAL B 1 556 ? 121.267 111.598 168.075 1.00 83.15  ? 556 VAL B O   1 
ATOM   8663  C CB  . VAL B 1 556 ? 119.714 113.583 165.918 1.00 75.27  ? 556 VAL B CB  1 
ATOM   8664  C CG1 . VAL B 1 556 ? 118.695 113.311 167.018 1.00 75.39  ? 556 VAL B CG1 1 
ATOM   8665  C CG2 . VAL B 1 556 ? 119.680 115.077 165.643 1.00 82.31  ? 556 VAL B CG2 1 
ATOM   8666  N N   . SER B 1 557 ? 121.080 110.727 166.029 1.00 85.43  ? 557 SER B N   1 
ATOM   8667  C CA  . SER B 1 557 ? 121.086 109.329 166.471 1.00 80.67  ? 557 SER B CA  1 
ATOM   8668  C C   . SER B 1 557 ? 122.406 108.924 167.122 1.00 79.59  ? 557 SER B C   1 
ATOM   8669  O O   . SER B 1 557 ? 122.405 108.174 168.090 1.00 78.40  ? 557 SER B O   1 
ATOM   8670  C CB  . SER B 1 557 ? 120.805 108.409 165.286 1.00 78.82  ? 557 SER B CB  1 
ATOM   8671  O OG  . SER B 1 557 ? 119.536 108.694 164.741 1.00 78.06  ? 557 SER B OG  1 
ATOM   8672  N N   . LEU B 1 558 ? 123.534 109.428 166.620 1.00 80.65  ? 558 LEU B N   1 
ATOM   8673  C CA  . LEU B 1 558 ? 124.866 109.060 167.090 1.00 77.52  ? 558 LEU B CA  1 
ATOM   8674  C C   . LEU B 1 558 ? 125.376 109.914 168.263 1.00 84.88  ? 558 LEU B C   1 
ATOM   8675  O O   . LEU B 1 558 ? 126.094 109.421 169.127 1.00 86.63  ? 558 LEU B O   1 
ATOM   8676  C CB  . LEU B 1 558 ? 125.801 109.142 165.880 1.00 71.01  ? 558 LEU B CB  1 
ATOM   8677  C CG  . LEU B 1 558 ? 127.098 108.351 166.018 1.00 81.43  ? 558 LEU B CG  1 
ATOM   8678  C CD1 . LEU B 1 558 ? 126.871 106.853 166.202 1.00 78.60  ? 558 LEU B CD1 1 
ATOM   8679  C CD2 . LEU B 1 558 ? 127.896 108.523 164.741 1.00 80.41  ? 558 LEU B CD2 1 
ATOM   8680  N N   . SER B 1 559 ? 124.971 111.185 168.339 1.00 88.53  ? 559 SER B N   1 
ATOM   8681  C CA  . SER B 1 559 ? 125.320 112.088 169.449 1.00 86.88  ? 559 SER B CA  1 
ATOM   8682  C C   . SER B 1 559 ? 124.518 111.833 170.732 1.00 93.63  ? 559 SER B C   1 
ATOM   8683  O O   . SER B 1 559 ? 124.677 112.551 171.719 1.00 95.76  ? 559 SER B O   1 
ATOM   8684  C CB  . SER B 1 559 ? 125.153 113.552 169.046 1.00 90.61  ? 559 SER B CB  1 
ATOM   8685  O OG  . SER B 1 559 ? 125.846 113.809 167.846 1.00 94.97  ? 559 SER B OG  1 
ATOM   8686  N N   . ARG B 1 560 ? 123.638 110.828 170.740 1.00 99.54  ? 560 ARG B N   1 
ATOM   8687  C CA  . ARG B 1 560 ? 122.809 110.446 171.889 1.00 99.51  ? 560 ARG B CA  1 
ATOM   8688  C C   . ARG B 1 560 ? 123.595 109.755 173.013 1.00 99.95  ? 560 ARG B C   1 
ATOM   8689  O O   . ARG B 1 560 ? 123.175 109.807 174.166 1.00 97.44  ? 560 ARG B O   1 
ATOM   8690  C CB  . ARG B 1 560 ? 121.672 109.569 171.346 1.00 101.03 ? 560 ARG B CB  1 
ATOM   8691  C CG  . ARG B 1 560 ? 120.474 109.479 172.297 1.00 100.93 ? 560 ARG B CG  1 
ATOM   8692  C CD  . ARG B 1 560 ? 119.366 108.583 171.727 1.00 101.54 ? 560 ARG B CD  1 
ATOM   8693  N NE  . ARG B 1 560 ? 118.799 109.103 170.468 1.00 101.57 ? 560 ARG B NE  1 
ATOM   8694  C CZ  . ARG B 1 560 ? 117.852 110.010 170.344 1.00 99.82  ? 560 ARG B CZ  1 
ATOM   8695  N NH1 . ARG B 1 560 ? 117.410 110.354 169.172 1.00 96.21  ? 560 ARG B NH1 1 
ATOM   8696  N NH2 . ARG B 1 560 ? 117.310 110.585 171.370 1.00 100.21 ? 560 ARG B NH2 1 
ATOM   8697  N N   . GLU B 1 561 ? 124.745 109.146 172.716 1.00 112.16 ? 561 GLU B N   1 
ATOM   8698  C CA  . GLU B 1 561 ? 125.532 108.363 173.682 1.00 115.04 ? 561 GLU B CA  1 
ATOM   8699  C C   . GLU B 1 561 ? 126.752 109.141 174.216 1.00 112.99 ? 561 GLU B C   1 
ATOM   8700  O O   . GLU B 1 561 ? 127.614 109.579 173.454 1.00 109.01 ? 561 GLU B O   1 
ATOM   8701  C CB  . GLU B 1 561 ? 125.988 107.032 173.047 1.00 114.67 ? 561 GLU B CB  1 
ATOM   8702  C CG  . GLU B 1 561 ? 124.854 106.147 172.508 1.00 111.78 ? 561 GLU B CG  1 
ATOM   8703  C CD  . GLU B 1 561 ? 123.702 105.944 173.507 1.00 115.59 ? 561 GLU B CD  1 
ATOM   8704  O OE1 . GLU B 1 561 ? 123.959 105.502 174.651 1.00 112.12 ? 561 GLU B OE1 1 
ATOM   8705  O OE2 . GLU B 1 561 ? 122.542 106.231 173.140 1.00 116.81 ? 561 GLU B OE2 1 
ATOM   8706  N N   . ALA B 1 562 ? 126.857 109.270 175.541 1.00 114.38 ? 562 ALA B N   1 
ATOM   8707  C CA  . ALA B 1 562 ? 128.006 109.855 176.239 1.00 115.32 ? 562 ALA B CA  1 
ATOM   8708  C C   . ALA B 1 562 ? 129.117 108.822 176.520 1.00 117.00 ? 562 ALA B C   1 
ATOM   8709  O O   . ALA B 1 562 ? 128.859 107.619 176.628 1.00 117.39 ? 562 ALA B O   1 
ATOM   8710  C CB  . ALA B 1 562 ? 127.505 110.518 177.521 1.00 110.72 ? 562 ALA B CB  1 
ATOM   8711  N N   . ARG B 1 563 ? 130.367 109.275 176.631 1.00 111.73 ? 563 ARG B N   1 
ATOM   8712  C CA  . ARG B 1 563 ? 131.549 108.420 176.764 1.00 111.25 ? 563 ARG B CA  1 
ATOM   8713  C C   . ARG B 1 563 ? 131.625 107.695 178.113 1.00 109.78 ? 563 ARG B C   1 
ATOM   8714  O O   . ARG B 1 563 ? 132.089 108.236 179.118 1.00 111.67 ? 563 ARG B O   1 
ATOM   8715  C CB  . ARG B 1 563 ? 132.800 109.257 176.505 1.00 107.83 ? 563 ARG B CB  1 
ATOM   8716  N N   . PRO B 1 589 ? 125.219 120.823 170.934 1.00 113.02 ? 589 PRO B N   1 
ATOM   8717  C CA  . PRO B 1 589 ? 124.791 120.489 169.585 1.00 112.47 ? 589 PRO B CA  1 
ATOM   8718  C C   . PRO B 1 589 ? 124.060 119.144 169.455 1.00 110.98 ? 589 PRO B C   1 
ATOM   8719  O O   . PRO B 1 589 ? 124.146 118.272 170.322 1.00 105.95 ? 589 PRO B O   1 
ATOM   8720  C CB  . PRO B 1 589 ? 126.075 120.526 168.753 1.00 112.55 ? 589 PRO B CB  1 
ATOM   8721  C CG  . PRO B 1 589 ? 126.888 121.612 169.441 1.00 108.68 ? 589 PRO B CG  1 
ATOM   8722  C CD  . PRO B 1 589 ? 126.552 121.387 170.911 1.00 111.28 ? 589 PRO B CD  1 
ATOM   8723  N N   . TYR B 1 590 ? 123.364 118.968 168.327 1.00 105.98 ? 590 TYR B N   1 
ATOM   8724  C CA  . TYR B 1 590 ? 122.767 117.701 167.868 1.00 103.67 ? 590 TYR B CA  1 
ATOM   8725  C C   . TYR B 1 590 ? 121.737 117.066 168.823 1.00 99.99  ? 590 TYR B C   1 
ATOM   8726  O O   . TYR B 1 590 ? 121.564 115.852 168.839 1.00 97.79  ? 590 TYR B O   1 
ATOM   8727  C CB  . TYR B 1 590 ? 123.874 116.680 167.586 1.00 100.81 ? 590 TYR B CB  1 
ATOM   8728  C CG  . TYR B 1 590 ? 125.057 117.240 166.840 1.00 101.34 ? 590 TYR B CG  1 
ATOM   8729  C CD1 . TYR B 1 590 ? 124.943 117.643 165.520 1.00 101.38 ? 590 TYR B CD1 1 
ATOM   8730  C CD2 . TYR B 1 590 ? 126.291 117.375 167.454 1.00 99.35  ? 590 TYR B CD2 1 
ATOM   8731  C CE1 . TYR B 1 590 ? 126.023 118.165 164.828 1.00 102.83 ? 590 TYR B CE1 1 
ATOM   8732  C CE2 . TYR B 1 590 ? 127.381 117.894 166.778 1.00 100.41 ? 590 TYR B CE2 1 
ATOM   8733  C CZ  . TYR B 1 590 ? 127.247 118.290 165.460 1.00 103.77 ? 590 TYR B CZ  1 
ATOM   8734  O OH  . TYR B 1 590 ? 128.317 118.804 164.788 1.00 102.97 ? 590 TYR B OH  1 
ATOM   8735  N N   . ARG B 1 591 ? 121.030 117.876 169.615 1.00 103.48 ? 591 ARG B N   1 
ATOM   8736  C CA  . ARG B 1 591 ? 120.024 117.409 170.572 1.00 104.14 ? 591 ARG B CA  1 
ATOM   8737  C C   . ARG B 1 591 ? 118.690 116.987 169.938 1.00 103.67 ? 591 ARG B C   1 
ATOM   8738  O O   . ARG B 1 591 ? 117.963 116.171 170.504 1.00 103.73 ? 591 ARG B O   1 
ATOM   8739  C CB  . ARG B 1 591 ? 119.771 118.528 171.574 1.00 98.86  ? 591 ARG B CB  1 
ATOM   8740  N N   . SER B 1 592 ? 118.346 117.534 168.770 1.00 91.79  ? 592 SER B N   1 
ATOM   8741  C CA  . SER B 1 592 ? 117.069 117.308 168.080 1.00 92.93  ? 592 SER B CA  1 
ATOM   8742  C C   . SER B 1 592 ? 117.224 117.465 166.569 1.00 91.19  ? 592 SER B C   1 
ATOM   8743  O O   . SER B 1 592 ? 118.224 118.007 166.103 1.00 91.10  ? 592 SER B O   1 
ATOM   8744  C CB  . SER B 1 592 ? 115.984 118.260 168.607 1.00 94.20  ? 592 SER B CB  1 
ATOM   8745  O OG  . SER B 1 592 ? 116.108 119.564 168.071 1.00 98.00  ? 592 SER B OG  1 
ATOM   8746  N N   . ILE B 1 593 ? 116.245 117.016 165.778 1.00 90.67  ? 593 ILE B N   1 
ATOM   8747  C CA  . ILE B 1 593 ? 116.288 117.146 164.312 1.00 90.67  ? 593 ILE B CA  1 
ATOM   8748  C C   . ILE B 1 593 ? 116.378 118.617 163.890 1.00 89.85  ? 593 ILE B C   1 
ATOM   8749  O O   . ILE B 1 593 ? 117.121 118.939 162.965 1.00 92.66  ? 593 ILE B O   1 
ATOM   8750  C CB  . ILE B 1 593 ? 115.069 116.471 163.638 1.00 92.36  ? 593 ILE B CB  1 
ATOM   8751  C CG1 . ILE B 1 593 ? 114.808 115.018 164.086 1.00 91.13  ? 593 ILE B CG1 1 
ATOM   8752  C CG2 . ILE B 1 593 ? 115.209 116.523 162.109 1.00 87.30  ? 593 ILE B CG2 1 
ATOM   8753  C CD1 . ILE B 1 593 ? 115.999 114.075 163.936 1.00 91.58  ? 593 ILE B CD1 1 
ATOM   8754  N N   . LEU B 1 594 ? 115.670 119.518 164.579 1.00 87.34  ? 594 LEU B N   1 
ATOM   8755  C CA  . LEU B 1 594 ? 115.726 120.959 164.335 1.00 90.86  ? 594 LEU B CA  1 
ATOM   8756  C C   . LEU B 1 594 ? 117.117 121.518 164.647 1.00 92.67  ? 594 LEU B C   1 
ATOM   8757  O O   . LEU B 1 594 ? 117.711 122.173 163.799 1.00 96.34  ? 594 LEU B O   1 
ATOM   8758  C CB  . LEU B 1 594 ? 114.625 121.651 165.160 1.00 95.30  ? 594 LEU B CB  1 
ATOM   8759  C CG  . LEU B 1 594 ? 114.661 123.191 165.127 1.00 96.66  ? 594 LEU B CG  1 
ATOM   8760  C CD1 . LEU B 1 594 ? 114.499 123.755 163.720 1.00 91.56  ? 594 LEU B CD1 1 
ATOM   8761  C CD2 . LEU B 1 594 ? 113.542 123.742 166.004 1.00 91.87  ? 594 LEU B CD2 1 
ATOM   8762  N N   . ASP B 1 595 ? 117.661 121.227 165.828 1.00 87.55  ? 595 ASP B N   1 
ATOM   8763  C CA  . ASP B 1 595 ? 118.978 121.724 166.229 1.00 85.20  ? 595 ASP B CA  1 
ATOM   8764  C C   . ASP B 1 595 ? 120.099 121.201 165.329 1.00 89.27  ? 595 ASP B C   1 
ATOM   8765  O O   . ASP B 1 595 ? 120.951 121.975 164.915 1.00 92.26  ? 595 ASP B O   1 
ATOM   8766  C CB  . ASP B 1 595 ? 119.263 121.358 167.689 1.00 94.94  ? 595 ASP B CB  1 
ATOM   8767  C CG  . ASP B 1 595 ? 118.229 121.937 168.652 1.00 101.45 ? 595 ASP B CG  1 
ATOM   8768  O OD1 . ASP B 1 595 ? 117.992 123.163 168.621 1.00 96.51  ? 595 ASP B OD1 1 
ATOM   8769  O OD2 . ASP B 1 595 ? 117.641 121.147 169.427 1.00 102.93 ? 595 ASP B OD2 1 
ATOM   8770  N N   . ALA B 1 596 ? 120.094 119.918 164.963 1.00 87.25  ? 596 ALA B N   1 
ATOM   8771  C CA  . ALA B 1 596 ? 121.060 119.363 164.021 1.00 80.05  ? 596 ALA B CA  1 
ATOM   8772  C C   . ALA B 1 596 ? 120.886 119.922 162.605 1.00 79.86  ? 596 ALA B C   1 
ATOM   8773  O O   . ALA B 1 596 ? 121.875 120.249 161.969 1.00 85.49  ? 596 ALA B O   1 
ATOM   8774  C CB  . ALA B 1 596 ? 120.950 117.846 164.036 1.00 78.13  ? 596 ALA B CB  1 
ATOM   8775  N N   . SER B 1 597 ? 119.658 120.119 162.122 1.00 80.04  ? 597 SER B N   1 
ATOM   8776  C CA  . SER B 1 597 ? 119.421 120.802 160.845 1.00 72.13  ? 597 SER B CA  1 
ATOM   8777  C C   . SER B 1 597 ? 119.947 122.230 160.869 1.00 73.22  ? 597 SER B C   1 
ATOM   8778  O O   . SER B 1 597 ? 120.486 122.692 159.875 1.00 81.98  ? 597 SER B O   1 
ATOM   8779  C CB  . SER B 1 597 ? 117.932 120.847 160.491 1.00 78.38  ? 597 SER B CB  1 
ATOM   8780  O OG  . SER B 1 597 ? 117.392 119.548 160.376 1.00 86.22  ? 597 SER B OG  1 
ATOM   8781  N N   . LEU B 1 598 ? 119.839 122.938 161.995 1.00 77.79  ? 598 LEU B N   1 
ATOM   8782  C CA  . LEU B 1 598 ? 120.332 124.301 162.128 1.00 80.55  ? 598 LEU B CA  1 
ATOM   8783  C C   . LEU B 1 598 ? 121.860 124.370 162.255 1.00 81.77  ? 598 LEU B C   1 
ATOM   8784  O O   . LEU B 1 598 ? 122.485 125.190 161.596 1.00 90.73  ? 598 LEU B O   1 
ATOM   8785  C CB  . LEU B 1 598 ? 119.597 124.964 163.300 1.00 76.49  ? 598 LEU B CB  1 
ATOM   8786  C CG  . LEU B 1 598 ? 119.755 126.486 163.332 1.00 83.69  ? 598 LEU B CG  1 
ATOM   8787  C CD1 . LEU B 1 598 ? 119.089 127.149 162.128 1.00 82.50  ? 598 LEU B CD1 1 
ATOM   8788  C CD2 . LEU B 1 598 ? 119.117 127.034 164.600 1.00 80.72  ? 598 LEU B CD2 1 
ATOM   8789  N N   . GLU B 1 599 ? 122.494 123.492 163.026 1.00 74.09  ? 599 GLU B N   1 
ATOM   8790  C CA  . GLU B 1 599 ? 123.956 123.386 163.106 1.00 68.33  ? 599 GLU B CA  1 
ATOM   8791  C C   . GLU B 1 599 ? 124.582 122.982 161.770 1.00 71.42  ? 599 GLU B C   1 
ATOM   8792  O O   . GLU B 1 599 ? 125.572 123.572 161.347 1.00 75.44  ? 599 GLU B O   1 
ATOM   8793  C CB  . GLU B 1 599 ? 124.353 122.371 164.189 1.00 78.34  ? 599 GLU B CB  1 
ATOM   8794  C CG  . GLU B 1 599 ? 124.097 122.837 165.631 1.00 82.84  ? 599 GLU B CG  1 
ATOM   8795  C CD  . GLU B 1 599 ? 124.762 124.177 165.980 1.00 84.59  ? 599 GLU B CD  1 
ATOM   8796  O OE1 . GLU B 1 599 ? 125.890 124.428 165.524 1.00 82.39  ? 599 GLU B OE1 1 
ATOM   8797  O OE2 . GLU B 1 599 ? 124.137 125.005 166.682 1.00 82.64  ? 599 GLU B OE2 1 
ATOM   8798  N N   . LEU B 1 600 ? 123.988 122.022 161.058 1.00 63.30  ? 600 LEU B N   1 
ATOM   8799  C CA  . LEU B 1 600 ? 124.386 121.672 159.699 1.00 51.34  ? 600 LEU B CA  1 
ATOM   8800  C C   . LEU B 1 600 ? 124.069 122.775 158.694 1.00 42.46  ? 600 LEU B C   1 
ATOM   8801  O O   . LEU B 1 600 ? 124.802 122.932 157.723 1.00 51.92  ? 600 LEU B O   1 
ATOM   8802  C CB  . LEU B 1 600 ? 123.679 120.391 159.260 1.00 64.09  ? 600 LEU B CB  1 
ATOM   8803  C CG  . LEU B 1 600 ? 124.130 119.086 159.918 1.00 53.68  ? 600 LEU B CG  1 
ATOM   8804  C CD1 . LEU B 1 600 ? 123.343 117.964 159.255 1.00 58.16  ? 600 LEU B CD1 1 
ATOM   8805  C CD2 . LEU B 1 600 ? 125.612 118.834 159.703 1.00 57.26  ? 600 LEU B CD2 1 
ATOM   8806  N N   . PHE B 1 601 ? 123.008 123.561 158.877 1.00 57.21  ? 601 PHE B N   1 
ATOM   8807  C CA  . PHE B 1 601 ? 122.761 124.685 157.980 1.00 62.58  ? 601 PHE B CA  1 
ATOM   8808  C C   . PHE B 1 601 ? 123.788 125.800 158.198 1.00 71.73  ? 601 PHE B C   1 
ATOM   8809  O O   . PHE B 1 601 ? 124.285 126.369 157.229 1.00 67.31  ? 601 PHE B O   1 
ATOM   8810  C CB  . PHE B 1 601 ? 121.335 125.216 158.133 1.00 60.29  ? 601 PHE B CB  1 
ATOM   8811  C CG  . PHE B 1 601 ? 121.078 126.414 157.247 1.00 67.25  ? 601 PHE B CG  1 
ATOM   8812  C CD1 . PHE B 1 601 ? 120.892 126.238 155.865 1.00 67.56  ? 601 PHE B CD1 1 
ATOM   8813  C CD2 . PHE B 1 601 ? 121.118 127.717 157.780 1.00 73.35  ? 601 PHE B CD2 1 
ATOM   8814  C CE1 . PHE B 1 601 ? 120.755 127.354 155.024 1.00 68.06  ? 601 PHE B CE1 1 
ATOM   8815  C CE2 . PHE B 1 601 ? 120.982 128.830 156.940 1.00 66.49  ? 601 PHE B CE2 1 
ATOM   8816  C CZ  . PHE B 1 601 ? 120.808 128.650 155.558 1.00 67.07  ? 601 PHE B CZ  1 
ATOM   8817  N N   . LYS B 1 602 ? 124.219 126.053 159.436 1.00 78.66  ? 602 LYS B N   1 
ATOM   8818  C CA  . LYS B 1 602 ? 125.223 127.071 159.726 1.00 54.48  ? 602 LYS B CA  1 
ATOM   8819  C C   . LYS B 1 602 ? 126.528 126.904 158.954 1.00 51.26  ? 602 LYS B C   1 
ATOM   8820  O O   . LYS B 1 602 ? 127.161 127.905 158.646 1.00 70.64  ? 602 LYS B O   1 
ATOM   8821  C CB  . LYS B 1 602 ? 125.477 127.165 161.228 1.00 61.47  ? 602 LYS B CB  1 
ATOM   8822  C CG  . LYS B 1 602 ? 124.466 128.092 161.901 1.00 62.44  ? 602 LYS B CG  1 
ATOM   8823  C CD  . LYS B 1 602 ? 124.859 128.402 163.348 1.00 62.42  ? 602 LYS B CD  1 
ATOM   8824  C CE  . LYS B 1 602 ? 124.526 127.224 164.257 1.00 70.18  ? 602 LYS B CE  1 
ATOM   8825  N NZ  . LYS B 1 602 ? 124.907 127.475 165.663 1.00 75.82  ? 602 LYS B NZ  1 
ATOM   8826  N N   . PHE B 1 603 ? 126.912 125.706 158.516 1.00 66.12  ? 603 PHE B N   1 
ATOM   8827  C CA  . PHE B 1 603 ? 128.077 125.497 157.637 1.00 71.80  ? 603 PHE B CA  1 
ATOM   8828  C C   . PHE B 1 603 ? 127.999 126.211 156.282 1.00 71.13  ? 603 PHE B C   1 
ATOM   8829  O O   . PHE B 1 603 ? 129.036 126.479 155.684 1.00 73.97  ? 603 PHE B O   1 
ATOM   8830  C CB  . PHE B 1 603 ? 128.258 124.009 157.350 1.00 65.53  ? 603 PHE B CB  1 
ATOM   8831  C CG  . PHE B 1 603 ? 128.964 123.246 158.440 1.00 67.28  ? 603 PHE B CG  1 
ATOM   8832  C CD1 . PHE B 1 603 ? 130.363 123.187 158.444 1.00 65.03  ? 603 PHE B CD1 1 
ATOM   8833  C CD2 . PHE B 1 603 ? 128.231 122.597 159.441 1.00 67.75  ? 603 PHE B CD2 1 
ATOM   8834  C CE1 . PHE B 1 603 ? 131.029 122.444 159.428 1.00 63.33  ? 603 PHE B CE1 1 
ATOM   8835  C CE2 . PHE B 1 603 ? 128.899 121.855 160.430 1.00 66.60  ? 603 PHE B CE2 1 
ATOM   8836  C CZ  . PHE B 1 603 ? 130.293 121.775 160.420 1.00 66.74  ? 603 PHE B CZ  1 
ATOM   8837  N N   . THR B 1 604 ? 126.805 126.505 155.775 1.00 70.57  ? 604 THR B N   1 
ATOM   8838  C CA  . THR B 1 604 ? 126.641 127.209 154.495 1.00 63.22  ? 604 THR B CA  1 
ATOM   8839  C C   . THR B 1 604 ? 126.721 128.726 154.646 1.00 75.92  ? 604 THR B C   1 
ATOM   8840  O O   . THR B 1 604 ? 127.110 129.399 153.696 1.00 78.60  ? 604 THR B O   1 
ATOM   8841  C CB  . THR B 1 604 ? 125.340 126.831 153.794 1.00 63.29  ? 604 THR B CB  1 
ATOM   8842  O OG1 . THR B 1 604 ? 124.222 127.237 154.539 1.00 67.46  ? 604 THR B OG1 1 
ATOM   8843  C CG2 . THR B 1 604 ? 125.242 125.336 153.547 1.00 75.10  ? 604 THR B CG2 1 
ATOM   8844  N N   . ILE B 1 605 ? 126.433 129.277 155.837 1.00 74.54  ? 605 ILE B N   1 
ATOM   8845  C CA  . ILE B 1 605 ? 126.653 130.705 156.134 1.00 64.19  ? 605 ILE B CA  1 
ATOM   8846  C C   . ILE B 1 605 ? 128.068 131.011 156.674 1.00 63.45  ? 605 ILE B C   1 
ATOM   8847  O O   . ILE B 1 605 ? 128.345 132.143 157.050 1.00 66.40  ? 605 ILE B O   1 
ATOM   8848  C CB  . ILE B 1 605 ? 125.544 131.266 157.043 1.00 58.94  ? 605 ILE B CB  1 
ATOM   8849  C CG1 . ILE B 1 605 ? 125.615 130.743 158.485 1.00 61.60  ? 605 ILE B CG1 1 
ATOM   8850  C CG2 . ILE B 1 605 ? 124.167 130.999 156.429 1.00 59.44  ? 605 ILE B CG2 1 
ATOM   8851  C CD1 . ILE B 1 605 ? 124.799 131.551 159.486 1.00 56.83  ? 605 ILE B CD1 1 
ATOM   8852  N N   . GLY B 1 606 ? 128.955 130.014 156.730 1.00 59.82  ? 606 GLY B N   1 
ATOM   8853  C CA  . GLY B 1 606 ? 130.324 130.137 157.226 1.00 56.98  ? 606 GLY B CA  1 
ATOM   8854  C C   . GLY B 1 606 ? 130.499 130.046 158.746 1.00 69.22  ? 606 GLY B C   1 
ATOM   8855  O O   . GLY B 1 606 ? 131.575 130.381 159.228 1.00 75.55  ? 606 GLY B O   1 
ATOM   8856  N N   . MET B 1 607 ? 129.488 129.595 159.507 1.00 67.07  ? 607 MET B N   1 
ATOM   8857  C CA  . MET B 1 607 ? 129.487 129.532 160.983 1.00 64.06  ? 607 MET B CA  1 
ATOM   8858  C C   . MET B 1 607 ? 129.519 128.094 161.521 1.00 62.34  ? 607 MET B C   1 
ATOM   8859  O O   . MET B 1 607 ? 128.794 127.747 162.443 1.00 67.09  ? 607 MET B O   1 
ATOM   8860  C CB  . MET B 1 607 ? 128.322 130.359 161.556 1.00 64.06  ? 607 MET B CB  1 
ATOM   8861  C CG  . MET B 1 607 ? 128.519 131.867 161.378 1.00 61.75  ? 607 MET B CG  1 
ATOM   8862  S SD  . MET B 1 607 ? 129.716 132.642 162.496 1.00 63.01  ? 607 MET B SD  1 
ATOM   8863  C CE  . MET B 1 607 ? 128.793 132.735 164.043 1.00 60.99  ? 607 MET B CE  1 
ATOM   8864  N N   . GLY B 1 608 ? 130.304 127.213 160.898 1.00 67.37  ? 608 GLY B N   1 
ATOM   8865  C CA  . GLY B 1 608 ? 130.191 125.757 161.028 1.00 67.92  ? 608 GLY B CA  1 
ATOM   8866  C C   . GLY B 1 608 ? 130.334 125.123 162.422 1.00 74.14  ? 608 GLY B C   1 
ATOM   8867  O O   . GLY B 1 608 ? 129.667 124.136 162.694 1.00 85.52  ? 608 GLY B O   1 
ATOM   8868  N N   . GLU B 1 609 ? 131.182 125.639 163.314 1.00 87.10  ? 609 GLU B N   1 
ATOM   8869  C CA  . GLU B 1 609 ? 131.418 125.038 164.650 1.00 91.22  ? 609 GLU B CA  1 
ATOM   8870  C C   . GLU B 1 609 ? 131.883 123.559 164.584 1.00 89.62  ? 609 GLU B C   1 
ATOM   8871  O O   . GLU B 1 609 ? 131.459 122.700 165.355 1.00 88.49  ? 609 GLU B O   1 
ATOM   8872  C CB  . GLU B 1 609 ? 130.232 125.279 165.620 1.00 91.12  ? 609 GLU B CB  1 
ATOM   8873  C CG  . GLU B 1 609 ? 129.903 126.769 165.820 1.00 95.08  ? 609 GLU B CG  1 
ATOM   8874  C CD  . GLU B 1 609 ? 128.685 126.990 166.733 1.00 97.36  ? 609 GLU B CD  1 
ATOM   8875  O OE1 . GLU B 1 609 ? 128.766 126.636 167.931 1.00 93.83  ? 609 GLU B OE1 1 
ATOM   8876  O OE2 . GLU B 1 609 ? 127.672 127.579 166.281 1.00 98.11  ? 609 GLU B OE2 1 
ATOM   8877  N N   . LEU B 1 610 ? 132.778 123.258 163.639 1.00 81.33  ? 610 LEU B N   1 
ATOM   8878  C CA  . LEU B 1 610 ? 133.381 121.944 163.390 1.00 77.94  ? 610 LEU B CA  1 
ATOM   8879  C C   . LEU B 1 610 ? 134.419 121.560 164.464 1.00 80.86  ? 610 LEU B C   1 
ATOM   8880  O O   . LEU B 1 610 ? 135.461 122.201 164.566 1.00 84.45  ? 610 LEU B O   1 
ATOM   8881  C CB  . LEU B 1 610 ? 134.015 122.039 161.991 1.00 80.88  ? 610 LEU B CB  1 
ATOM   8882  C CG  . LEU B 1 610 ? 134.727 120.793 161.469 1.00 81.44  ? 610 LEU B CG  1 
ATOM   8883  C CD1 . LEU B 1 610 ? 133.793 119.608 161.282 1.00 83.52  ? 610 LEU B CD1 1 
ATOM   8884  C CD2 . LEU B 1 610 ? 135.315 121.110 160.105 1.00 81.25  ? 610 LEU B CD2 1 
ATOM   8885  N N   . ALA B 1 611 ? 134.171 120.519 165.260 1.00 99.90  ? 611 ALA B N   1 
ATOM   8886  C CA  . ALA B 1 611 ? 135.015 120.170 166.408 1.00 99.36  ? 611 ALA B CA  1 
ATOM   8887  C C   . ALA B 1 611 ? 134.991 118.675 166.768 1.00 101.47 ? 611 ALA B C   1 
ATOM   8888  O O   . ALA B 1 611 ? 134.013 117.973 166.517 1.00 103.85 ? 611 ALA B O   1 
ATOM   8889  C CB  . ALA B 1 611 ? 134.564 121.006 167.612 1.00 96.19  ? 611 ALA B CB  1 
ATOM   8890  N N   . PHE B 1 612 ? 136.053 118.202 167.422 1.00 106.52 ? 612 PHE B N   1 
ATOM   8891  C CA  . PHE B 1 612 ? 136.147 116.868 168.017 1.00 105.40 ? 612 PHE B CA  1 
ATOM   8892  C C   . PHE B 1 612 ? 135.512 116.874 169.420 1.00 106.94 ? 612 PHE B C   1 
ATOM   8893  O O   . PHE B 1 612 ? 136.182 117.155 170.412 1.00 108.04 ? 612 PHE B O   1 
ATOM   8894  C CB  . PHE B 1 612 ? 137.631 116.467 168.018 1.00 105.42 ? 612 PHE B CB  1 
ATOM   8895  C CG  . PHE B 1 612 ? 137.937 115.049 168.447 1.00 108.01 ? 612 PHE B CG  1 
ATOM   8896  C CD1 . PHE B 1 612 ? 137.721 113.983 167.559 1.00 106.04 ? 612 PHE B CD1 1 
ATOM   8897  C CD2 . PHE B 1 612 ? 138.517 114.796 169.704 1.00 106.98 ? 612 PHE B CD2 1 
ATOM   8898  C CE1 . PHE B 1 612 ? 138.096 112.679 167.911 1.00 106.21 ? 612 PHE B CE1 1 
ATOM   8899  C CE2 . PHE B 1 612 ? 138.902 113.491 170.054 1.00 105.99 ? 612 PHE B CE2 1 
ATOM   8900  C CZ  . PHE B 1 612 ? 138.693 112.431 169.159 1.00 106.30 ? 612 PHE B CZ  1 
ATOM   8901  N N   . GLN B 1 613 ? 134.200 116.629 169.500 1.00 111.68 ? 613 GLN B N   1 
ATOM   8902  C CA  . GLN B 1 613 ? 133.400 116.765 170.727 1.00 113.07 ? 613 GLN B CA  1 
ATOM   8903  C C   . GLN B 1 613 ? 133.893 115.825 171.841 1.00 112.93 ? 613 GLN B C   1 
ATOM   8904  O O   . GLN B 1 613 ? 133.847 114.609 171.686 1.00 112.90 ? 613 GLN B O   1 
ATOM   8905  C CB  . GLN B 1 613 ? 131.925 116.447 170.409 1.00 109.90 ? 613 GLN B CB  1 
ATOM   8906  C CG  . GLN B 1 613 ? 131.253 117.351 169.362 1.00 111.97 ? 613 GLN B CG  1 
ATOM   8907  C CD  . GLN B 1 613 ? 131.008 118.786 169.820 1.00 115.79 ? 613 GLN B CD  1 
ATOM   8908  O OE1 . GLN B 1 613 ? 131.192 119.160 170.968 1.00 115.54 ? 613 GLN B OE1 1 
ATOM   8909  N NE2 . GLN B 1 613 ? 130.575 119.654 168.937 1.00 110.67 ? 613 GLN B NE2 1 
ATOM   8910  N N   . GLU B 1 614 ? 134.365 116.330 172.981 1.00 118.01 ? 614 GLU B N   1 
ATOM   8911  C CA  . GLU B 1 614 ? 135.061 115.481 173.961 1.00 118.38 ? 614 GLU B CA  1 
ATOM   8912  C C   . GLU B 1 614 ? 134.150 114.469 174.687 1.00 121.37 ? 614 GLU B C   1 
ATOM   8913  O O   . GLU B 1 614 ? 134.604 113.374 175.017 1.00 120.85 ? 614 GLU B O   1 
ATOM   8914  C CB  . GLU B 1 614 ? 135.793 116.339 175.005 1.00 117.04 ? 614 GLU B CB  1 
ATOM   8915  N N   . GLN B 1 615 ? 132.887 114.815 174.951 1.00 118.27 ? 615 GLN B N   1 
ATOM   8916  C CA  . GLN B 1 615 ? 131.984 114.046 175.815 1.00 115.14 ? 615 GLN B CA  1 
ATOM   8917  C C   . GLN B 1 615 ? 131.215 112.917 175.110 1.00 116.41 ? 615 GLN B C   1 
ATOM   8918  O O   . GLN B 1 615 ? 130.693 112.027 175.781 1.00 118.78 ? 615 GLN B O   1 
ATOM   8919  C CB  . GLN B 1 615 ? 131.029 115.005 176.557 1.00 112.47 ? 615 GLN B CB  1 
ATOM   8920  C CG  . GLN B 1 615 ? 129.735 115.439 175.838 1.00 113.92 ? 615 GLN B CG  1 
ATOM   8921  C CD  . GLN B 1 615 ? 129.910 116.420 174.680 1.00 117.31 ? 615 GLN B CD  1 
ATOM   8922  O OE1 . GLN B 1 615 ? 131.004 116.741 174.243 1.00 117.97 ? 615 GLN B OE1 1 
ATOM   8923  N NE2 . GLN B 1 615 ? 128.833 116.937 174.137 1.00 115.18 ? 615 GLN B NE2 1 
ATOM   8924  N N   . LEU B 1 616 ? 131.104 112.951 173.777 1.00 106.51 ? 616 LEU B N   1 
ATOM   8925  C CA  . LEU B 1 616 ? 130.363 111.953 172.998 1.00 106.35 ? 616 LEU B CA  1 
ATOM   8926  C C   . LEU B 1 616 ? 131.136 110.629 172.913 1.00 106.12 ? 616 LEU B C   1 
ATOM   8927  O O   . LEU B 1 616 ? 132.352 110.632 172.736 1.00 107.10 ? 616 LEU B O   1 
ATOM   8928  C CB  . LEU B 1 616 ? 130.048 112.493 171.586 1.00 104.60 ? 616 LEU B CB  1 
ATOM   8929  C CG  . LEU B 1 616 ? 129.211 113.782 171.534 1.00 104.31 ? 616 LEU B CG  1 
ATOM   8930  C CD1 . LEU B 1 616 ? 128.924 114.147 170.081 1.00 101.63 ? 616 LEU B CD1 1 
ATOM   8931  C CD2 . LEU B 1 616 ? 127.874 113.633 172.254 1.00 104.26 ? 616 LEU B CD2 1 
ATOM   8932  N N   . ARG B 1 617 ? 130.451 109.479 172.972 1.00 95.70  ? 617 ARG B N   1 
ATOM   8933  C CA  . ARG B 1 617 ? 131.133 108.149 172.915 1.00 95.42  ? 617 ARG B CA  1 
ATOM   8934  C C   . ARG B 1 617 ? 131.720 107.921 171.530 1.00 97.10  ? 617 ARG B C   1 
ATOM   8935  O O   . ARG B 1 617 ? 132.854 107.438 171.456 1.00 91.06  ? 617 ARG B O   1 
ATOM   8936  C CB  . ARG B 1 617 ? 130.133 107.035 173.223 1.00 90.97  ? 617 ARG B CB  1 
ATOM   8937  C CG  . ARG B 1 617 ? 130.738 105.654 173.420 1.00 90.08  ? 617 ARG B CG  1 
ATOM   8938  C CD  . ARG B 1 617 ? 129.598 104.659 173.508 1.00 95.52  ? 617 ARG B CD  1 
ATOM   8939  N NE  . ARG B 1 617 ? 129.874 103.422 174.224 1.00 98.54  ? 617 ARG B NE  1 
ATOM   8940  C CZ  . ARG B 1 617 ? 130.332 102.307 173.668 1.00 98.75  ? 617 ARG B CZ  1 
ATOM   8941  N NH1 . ARG B 1 617 ? 130.539 101.235 174.412 1.00 96.79  ? 617 ARG B NH1 1 
ATOM   8942  N NH2 . ARG B 1 617 ? 130.591 102.265 172.375 1.00 98.63  ? 617 ARG B NH2 1 
ATOM   8943  N N   . PHE B 1 618 ? 130.970 108.250 170.482 1.00 96.62  ? 618 PHE B N   1 
ATOM   8944  C CA  . PHE B 1 618 ? 131.342 108.087 169.074 1.00 90.72  ? 618 PHE B CA  1 
ATOM   8945  C C   . PHE B 1 618 ? 131.902 109.380 168.456 1.00 92.95  ? 618 PHE B C   1 
ATOM   8946  O O   . PHE B 1 618 ? 131.674 109.658 167.282 1.00 95.13  ? 618 PHE B O   1 
ATOM   8947  C CB  . PHE B 1 618 ? 130.136 107.532 168.303 1.00 89.94  ? 618 PHE B CB  1 
ATOM   8948  C CG  . PHE B 1 618 ? 129.601 106.221 168.841 1.00 89.91  ? 618 PHE B CG  1 
ATOM   8949  C CD1 . PHE B 1 618 ? 130.344 105.039 168.686 1.00 86.79  ? 618 PHE B CD1 1 
ATOM   8950  C CD2 . PHE B 1 618 ? 128.371 106.185 169.515 1.00 89.34  ? 618 PHE B CD2 1 
ATOM   8951  C CE1 . PHE B 1 618 ? 129.869 103.832 169.222 1.00 84.37  ? 618 PHE B CE1 1 
ATOM   8952  C CE2 . PHE B 1 618 ? 127.899 104.980 170.054 1.00 90.64  ? 618 PHE B CE2 1 
ATOM   8953  C CZ  . PHE B 1 618 ? 128.644 103.803 169.907 1.00 88.47  ? 618 PHE B CZ  1 
ATOM   8954  N N   . ARG B 1 619 ? 132.588 110.220 169.233 1.00 102.49 ? 619 ARG B N   1 
ATOM   8955  C CA  . ARG B 1 619 ? 133.054 111.567 168.774 1.00 97.93  ? 619 ARG B CA  1 
ATOM   8956  C C   . ARG B 1 619 ? 133.898 111.563 167.494 1.00 96.19  ? 619 ARG B C   1 
ATOM   8957  O O   . ARG B 1 619 ? 133.857 112.573 166.797 1.00 97.02  ? 619 ARG B O   1 
ATOM   8958  C CB  . ARG B 1 619 ? 133.837 112.231 169.907 1.00 102.06 ? 619 ARG B CB  1 
ATOM   8959  C CG  . ARG B 1 619 ? 135.133 111.526 170.275 1.00 100.28 ? 619 ARG B CG  1 
ATOM   8960  C CD  . ARG B 1 619 ? 135.675 112.043 171.589 1.00 100.09 ? 619 ARG B CD  1 
ATOM   8961  N NE  . ARG B 1 619 ? 136.808 111.250 172.037 1.00 103.79 ? 619 ARG B NE  1 
ATOM   8962  C CZ  . ARG B 1 619 ? 137.402 111.393 173.214 1.00 102.50 ? 619 ARG B CZ  1 
ATOM   8963  N NH1 . ARG B 1 619 ? 138.431 110.626 173.531 1.00 98.34  ? 619 ARG B NH1 1 
ATOM   8964  N NH2 . ARG B 1 619 ? 136.964 112.297 174.070 1.00 100.97 ? 619 ARG B NH2 1 
ATOM   8965  N N   . GLY B 1 620 ? 134.712 110.551 167.241 1.00 83.47  ? 620 GLY B N   1 
ATOM   8966  C CA  . GLY B 1 620 ? 135.435 110.441 165.973 1.00 87.03  ? 620 GLY B CA  1 
ATOM   8967  C C   . GLY B 1 620 ? 134.518 110.167 164.781 1.00 87.54  ? 620 GLY B C   1 
ATOM   8968  O O   . GLY B 1 620 ? 134.723 110.713 163.703 1.00 84.70  ? 620 GLY B O   1 
ATOM   8969  N N   . VAL B 1 621 ? 133.460 109.378 164.968 1.00 88.88  ? 621 VAL B N   1 
ATOM   8970  C CA  . VAL B 1 621 ? 132.478 109.086 163.914 1.00 86.75  ? 621 VAL B CA  1 
ATOM   8971  C C   . VAL B 1 621 ? 131.559 110.284 163.679 1.00 83.70  ? 621 VAL B C   1 
ATOM   8972  O O   . VAL B 1 621 ? 131.260 110.602 162.537 1.00 86.47  ? 621 VAL B O   1 
ATOM   8973  C CB  . VAL B 1 621 ? 131.664 107.817 164.216 1.00 85.17  ? 621 VAL B CB  1 
ATOM   8974  C CG1 . VAL B 1 621 ? 130.841 107.419 162.989 1.00 84.69  ? 621 VAL B CG1 1 
ATOM   8975  C CG2 . VAL B 1 621 ? 132.547 106.619 164.575 1.00 87.41  ? 621 VAL B CG2 1 
ATOM   8976  N N   . VAL B 1 622 ? 131.171 111.007 164.731 1.00 79.29  ? 622 VAL B N   1 
ATOM   8977  C CA  . VAL B 1 622 ? 130.450 112.286 164.620 1.00 77.91  ? 622 VAL B CA  1 
ATOM   8978  C C   . VAL B 1 622 ? 131.280 113.318 163.847 1.00 81.86  ? 622 VAL B C   1 
ATOM   8979  O O   . VAL B 1 622 ? 130.755 113.934 162.928 1.00 86.44  ? 622 VAL B O   1 
ATOM   8980  C CB  . VAL B 1 622 ? 130.022 112.793 166.010 1.00 77.61  ? 622 VAL B CB  1 
ATOM   8981  C CG1 . VAL B 1 622 ? 129.458 114.204 166.004 1.00 74.93  ? 622 VAL B CG1 1 
ATOM   8982  C CG2 . VAL B 1 622 ? 128.943 111.887 166.597 1.00 82.01  ? 622 VAL B CG2 1 
ATOM   8983  N N   . LEU B 1 623 ? 132.584 113.464 164.118 1.00 82.46  ? 623 LEU B N   1 
ATOM   8984  C CA  . LEU B 1 623 ? 133.469 114.324 163.324 1.00 77.19  ? 623 LEU B CA  1 
ATOM   8985  C C   . LEU B 1 623 ? 133.605 113.853 161.863 1.00 81.14  ? 623 LEU B C   1 
ATOM   8986  O O   . LEU B 1 623 ? 133.526 114.674 160.953 1.00 83.16  ? 623 LEU B O   1 
ATOM   8987  C CB  . LEU B 1 623 ? 134.834 114.440 164.022 1.00 80.30  ? 623 LEU B CB  1 
ATOM   8988  C CG  . LEU B 1 623 ? 135.868 115.280 163.253 1.00 84.94  ? 623 LEU B CG  1 
ATOM   8989  C CD1 . LEU B 1 623 ? 135.429 116.728 163.086 1.00 85.90  ? 623 LEU B CD1 1 
ATOM   8990  C CD2 . LEU B 1 623 ? 137.209 115.273 163.974 1.00 84.90  ? 623 LEU B CD2 1 
ATOM   8991  N N   . LEU B 1 624 ? 133.753 112.556 161.596 1.00 82.30  ? 624 LEU B N   1 
ATOM   8992  C CA  . LEU B 1 624 ? 133.741 112.033 160.227 1.00 80.87  ? 624 LEU B CA  1 
ATOM   8993  C C   . LEU B 1 624 ? 132.403 112.273 159.508 1.00 85.10  ? 624 LEU B C   1 
ATOM   8994  O O   . LEU B 1 624 ? 132.425 112.571 158.319 1.00 89.23  ? 624 LEU B O   1 
ATOM   8995  C CB  . LEU B 1 624 ? 134.100 110.541 160.231 1.00 82.26  ? 624 LEU B CB  1 
ATOM   8996  C CG  . LEU B 1 624 ? 135.582 110.261 160.522 1.00 84.71  ? 624 LEU B CG  1 
ATOM   8997  C CD1 . LEU B 1 624 ? 135.779 108.786 160.857 1.00 83.82  ? 624 LEU B CD1 1 
ATOM   8998  C CD2 . LEU B 1 624 ? 136.461 110.594 159.320 1.00 82.11  ? 624 LEU B CD2 1 
ATOM   8999  N N   . LEU B 1 625 ? 131.251 112.210 160.188 1.00 74.77  ? 625 LEU B N   1 
ATOM   9000  C CA  . LEU B 1 625 ? 129.960 112.590 159.609 1.00 69.72  ? 625 LEU B CA  1 
ATOM   9001  C C   . LEU B 1 625 ? 129.895 114.077 159.258 1.00 79.57  ? 625 LEU B C   1 
ATOM   9002  O O   . LEU B 1 625 ? 129.373 114.417 158.203 1.00 89.46  ? 625 LEU B O   1 
ATOM   9003  C CB  . LEU B 1 625 ? 128.809 112.236 160.558 1.00 72.98  ? 625 LEU B CB  1 
ATOM   9004  C CG  . LEU B 1 625 ? 128.385 110.764 160.566 1.00 82.33  ? 625 LEU B CG  1 
ATOM   9005  C CD1 . LEU B 1 625 ? 127.281 110.558 161.587 1.00 77.69  ? 625 LEU B CD1 1 
ATOM   9006  C CD2 . LEU B 1 625 ? 127.836 110.324 159.217 1.00 79.18  ? 625 LEU B CD2 1 
ATOM   9007  N N   . LEU B 1 626 ? 130.446 114.971 160.083 1.00 74.79  ? 626 LEU B N   1 
ATOM   9008  C CA  . LEU B 1 626 ? 130.546 116.391 159.729 1.00 66.02  ? 626 LEU B CA  1 
ATOM   9009  C C   . LEU B 1 626 ? 131.491 116.618 158.552 1.00 68.15  ? 626 LEU B C   1 
ATOM   9010  O O   . LEU B 1 626 ? 131.144 117.353 157.639 1.00 70.25  ? 626 LEU B O   1 
ATOM   9011  C CB  . LEU B 1 626 ? 131.015 117.227 160.922 1.00 66.93  ? 626 LEU B CB  1 
ATOM   9012  C CG  . LEU B 1 626 ? 130.057 117.254 162.112 1.00 71.44  ? 626 LEU B CG  1 
ATOM   9013  C CD1 . LEU B 1 626 ? 130.740 117.961 163.275 1.00 68.35  ? 626 LEU B CD1 1 
ATOM   9014  C CD2 . LEU B 1 626 ? 128.765 117.986 161.771 1.00 67.91  ? 626 LEU B CD2 1 
ATOM   9015  N N   . LEU B 1 627 ? 132.661 115.980 158.520 1.00 71.49  ? 627 LEU B N   1 
ATOM   9016  C CA  . LEU B 1 627 ? 133.599 116.094 157.399 1.00 69.99  ? 627 LEU B CA  1 
ATOM   9017  C C   . LEU B 1 627 ? 133.022 115.517 156.103 1.00 71.65  ? 627 LEU B C   1 
ATOM   9018  O O   . LEU B 1 627 ? 133.208 116.102 155.044 1.00 73.92  ? 627 LEU B O   1 
ATOM   9019  C CB  . LEU B 1 627 ? 134.930 115.417 157.760 1.00 70.80  ? 627 LEU B CB  1 
ATOM   9020  C CG  . LEU B 1 627 ? 135.735 116.151 158.844 1.00 69.43  ? 627 LEU B CG  1 
ATOM   9021  C CD1 . LEU B 1 627 ? 136.917 115.289 159.264 1.00 69.66  ? 627 LEU B CD1 1 
ATOM   9022  C CD2 . LEU B 1 627 ? 136.271 117.486 158.345 1.00 72.81  ? 627 LEU B CD2 1 
ATOM   9023  N N   . ALA B 1 628 ? 132.265 114.422 156.167 1.00 74.27  ? 628 ALA B N   1 
ATOM   9024  C CA  . ALA B 1 628 ? 131.483 113.928 155.041 1.00 66.60  ? 628 ALA B CA  1 
ATOM   9025  C C   . ALA B 1 628 ? 130.424 114.939 154.593 1.00 70.31  ? 628 ALA B C   1 
ATOM   9026  O O   . ALA B 1 628 ? 130.389 115.271 153.413 1.00 76.15  ? 628 ALA B O   1 
ATOM   9027  C CB  . ALA B 1 628 ? 130.859 112.589 155.425 1.00 61.38  ? 628 ALA B CB  1 
ATOM   9028  N N   . TYR B 1 629 ? 129.617 115.512 155.492 1.00 58.50  ? 629 TYR B N   1 
ATOM   9029  C CA  . TYR B 1 629 ? 128.630 116.533 155.119 1.00 56.25  ? 629 TYR B CA  1 
ATOM   9030  C C   . TYR B 1 629 ? 129.277 117.769 154.492 1.00 62.59  ? 629 TYR B C   1 
ATOM   9031  O O   . TYR B 1 629 ? 128.816 118.222 153.446 1.00 73.34  ? 629 TYR B O   1 
ATOM   9032  C CB  . TYR B 1 629 ? 127.765 116.920 156.325 1.00 58.50  ? 629 TYR B CB  1 
ATOM   9033  C CG  . TYR B 1 629 ? 126.895 118.147 156.103 1.00 58.38  ? 629 TYR B CG  1 
ATOM   9034  C CD1 . TYR B 1 629 ? 125.656 118.056 155.434 1.00 54.72  ? 629 TYR B CD1 1 
ATOM   9035  C CD2 . TYR B 1 629 ? 127.356 119.397 156.541 1.00 60.10  ? 629 TYR B CD2 1 
ATOM   9036  C CE1 . TYR B 1 629 ? 124.894 119.216 155.190 1.00 56.62  ? 629 TYR B CE1 1 
ATOM   9037  C CE2 . TYR B 1 629 ? 126.594 120.550 156.306 1.00 67.78  ? 629 TYR B CE2 1 
ATOM   9038  C CZ  . TYR B 1 629 ? 125.366 120.476 155.622 1.00 69.10  ? 629 TYR B CZ  1 
ATOM   9039  O OH  . TYR B 1 629 ? 124.647 121.618 155.424 1.00 58.80  ? 629 TYR B OH  1 
ATOM   9040  N N   . VAL B 1 630 ? 130.350 118.307 155.074 1.00 63.56  ? 630 VAL B N   1 
ATOM   9041  C CA  . VAL B 1 630 ? 131.064 119.490 154.559 1.00 64.99  ? 630 VAL B CA  1 
ATOM   9042  C C   . VAL B 1 630 ? 131.586 119.243 153.157 1.00 62.84  ? 630 VAL B C   1 
ATOM   9043  O O   . VAL B 1 630 ? 131.306 120.018 152.251 1.00 66.65  ? 630 VAL B O   1 
ATOM   9044  C CB  . VAL B 1 630 ? 132.218 119.880 155.500 1.00 64.10  ? 630 VAL B CB  1 
ATOM   9045  C CG1 . VAL B 1 630 ? 133.189 120.896 154.894 1.00 61.26  ? 630 VAL B CG1 1 
ATOM   9046  C CG2 . VAL B 1 630 ? 131.666 120.518 156.768 1.00 63.37  ? 630 VAL B CG2 1 
ATOM   9047  N N   . LEU B 1 631 ? 132.321 118.150 152.940 1.00 66.46  ? 631 LEU B N   1 
ATOM   9048  C CA  . LEU B 1 631 ? 132.899 117.852 151.641 1.00 65.30  ? 631 LEU B CA  1 
ATOM   9049  C C   . LEU B 1 631 ? 131.814 117.612 150.596 1.00 66.00  ? 631 LEU B C   1 
ATOM   9050  O O   . LEU B 1 631 ? 131.855 118.235 149.542 1.00 70.06  ? 631 LEU B O   1 
ATOM   9051  C CB  . LEU B 1 631 ? 133.878 116.676 151.781 1.00 65.07  ? 631 LEU B CB  1 
ATOM   9052  C CG  . LEU B 1 631 ? 135.137 117.023 152.599 1.00 67.40  ? 631 LEU B CG  1 
ATOM   9053  C CD1 . LEU B 1 631 ? 135.949 115.763 152.862 1.00 69.73  ? 631 LEU B CD1 1 
ATOM   9054  C CD2 . LEU B 1 631 ? 136.045 118.005 151.872 1.00 65.19  ? 631 LEU B CD2 1 
ATOM   9055  N N   . LEU B 1 632 ? 130.788 116.807 150.886 1.00 67.20  ? 632 LEU B N   1 
ATOM   9056  C CA  . LEU B 1 632 ? 129.683 116.588 149.954 1.00 60.01  ? 632 LEU B CA  1 
ATOM   9057  C C   . LEU B 1 632 ? 128.909 117.867 149.641 1.00 58.09  ? 632 LEU B C   1 
ATOM   9058  O O   . LEU B 1 632 ? 128.582 118.115 148.486 1.00 68.09  ? 632 LEU B O   1 
ATOM   9059  C CB  . LEU B 1 632 ? 128.731 115.527 150.516 1.00 60.36  ? 632 LEU B CB  1 
ATOM   9060  C CG  . LEU B 1 632 ? 129.314 114.108 150.567 1.00 64.17  ? 632 LEU B CG  1 
ATOM   9061  C CD1 . LEU B 1 632 ? 128.256 113.175 151.144 1.00 65.19  ? 632 LEU B CD1 1 
ATOM   9062  C CD2 . LEU B 1 632 ? 129.699 113.588 149.188 1.00 64.52  ? 632 LEU B CD2 1 
ATOM   9063  N N   . THR B 1 633 ? 128.640 118.705 150.633 1.00 59.95  ? 633 THR B N   1 
ATOM   9064  C CA  . THR B 1 633 ? 127.930 119.979 150.463 1.00 62.05  ? 633 THR B CA  1 
ATOM   9065  C C   . THR B 1 633 ? 128.746 121.001 149.686 1.00 63.65  ? 633 THR B C   1 
ATOM   9066  O O   . THR B 1 633 ? 128.189 121.725 148.876 1.00 62.93  ? 633 THR B O   1 
ATOM   9067  C CB  . THR B 1 633 ? 127.554 120.561 151.825 1.00 57.87  ? 633 THR B CB  1 
ATOM   9068  O OG1 . THR B 1 633 ? 126.702 119.654 152.460 1.00 66.25  ? 633 THR B OG1 1 
ATOM   9069  C CG2 . THR B 1 633 ? 126.828 121.896 151.757 1.00 62.48  ? 633 THR B CG2 1 
ATOM   9070  N N   . TYR B 1 634 ? 130.059 121.087 149.883 1.00 73.12  ? 634 TYR B N   1 
ATOM   9071  C CA  . TYR B 1 634 ? 130.880 122.061 149.168 1.00 59.43  ? 634 TYR B CA  1 
ATOM   9072  C C   . TYR B 1 634 ? 131.156 121.596 147.733 1.00 65.11  ? 634 TYR B C   1 
ATOM   9073  O O   . TYR B 1 634 ? 131.151 122.421 146.830 1.00 71.64  ? 634 TYR B O   1 
ATOM   9074  C CB  . TYR B 1 634 ? 132.149 122.382 149.971 1.00 65.97  ? 634 TYR B CB  1 
ATOM   9075  C CG  . TYR B 1 634 ? 131.971 123.295 151.188 1.00 83.64  ? 634 TYR B CG  1 
ATOM   9076  C CD1 . TYR B 1 634 ? 130.747 123.408 151.881 1.00 81.25  ? 634 TYR B CD1 1 
ATOM   9077  C CD2 . TYR B 1 634 ? 133.061 124.069 151.624 1.00 73.69  ? 634 TYR B CD2 1 
ATOM   9078  C CE1 . TYR B 1 634 ? 130.608 124.271 152.977 1.00 73.79  ? 634 TYR B CE1 1 
ATOM   9079  C CE2 . TYR B 1 634 ? 132.923 124.940 152.717 1.00 71.23  ? 634 TYR B CE2 1 
ATOM   9080  C CZ  . TYR B 1 634 ? 131.692 125.047 153.400 1.00 74.15  ? 634 TYR B CZ  1 
ATOM   9081  O OH  . TYR B 1 634 ? 131.559 125.901 154.451 1.00 78.69  ? 634 TYR B OH  1 
ATOM   9082  N N   . VAL B 1 635 ? 131.261 120.290 147.468 1.00 68.64  ? 635 VAL B N   1 
ATOM   9083  C CA  . VAL B 1 635 ? 131.194 119.721 146.112 1.00 59.30  ? 635 VAL B CA  1 
ATOM   9084  C C   . VAL B 1 635 ? 129.846 120.022 145.446 1.00 59.44  ? 635 VAL B C   1 
ATOM   9085  O O   . VAL B 1 635 ? 129.819 120.440 144.295 1.00 68.21  ? 635 VAL B O   1 
ATOM   9086  C CB  . VAL B 1 635 ? 131.462 118.206 146.144 1.00 58.68  ? 635 VAL B CB  1 
ATOM   9087  C CG1 . VAL B 1 635 ? 131.254 117.521 144.795 1.00 67.70  ? 635 VAL B CG1 1 
ATOM   9088  C CG2 . VAL B 1 635 ? 132.907 117.923 146.541 1.00 58.60  ? 635 VAL B CG2 1 
ATOM   9089  N N   . LEU B 1 636 ? 128.721 119.877 146.152 1.00 52.16  ? 636 LEU B N   1 
ATOM   9090  C CA  . LEU B 1 636 ? 127.398 120.240 145.643 1.00 53.13  ? 636 LEU B CA  1 
ATOM   9091  C C   . LEU B 1 636 ? 127.279 121.741 145.342 1.00 60.50  ? 636 LEU B C   1 
ATOM   9092  O O   . LEU B 1 636 ? 126.800 122.089 144.268 1.00 71.99  ? 636 LEU B O   1 
ATOM   9093  C CB  . LEU B 1 636 ? 126.330 119.759 146.635 1.00 64.45  ? 636 LEU B CB  1 
ATOM   9094  C CG  . LEU B 1 636 ? 124.899 120.214 146.319 1.00 69.83  ? 636 LEU B CG  1 
ATOM   9095  C CD1 . LEU B 1 636 ? 124.369 119.577 145.040 1.00 61.35  ? 636 LEU B CD1 1 
ATOM   9096  C CD2 . LEU B 1 636 ? 123.980 119.866 147.482 1.00 62.85  ? 636 LEU B CD2 1 
ATOM   9097  N N   . LEU B 1 637 ? 127.710 122.639 146.222 1.00 62.63  ? 637 LEU B N   1 
ATOM   9098  C CA  . LEU B 1 637 ? 127.679 124.085 145.968 1.00 58.81  ? 637 LEU B CA  1 
ATOM   9099  C C   . LEU B 1 637 ? 128.585 124.471 144.795 1.00 58.59  ? 637 LEU B C   1 
ATOM   9100  O O   . LEU B 1 637 ? 128.215 125.312 143.995 1.00 63.27  ? 637 LEU B O   1 
ATOM   9101  C CB  . LEU B 1 637 ? 128.068 124.860 147.235 1.00 65.31  ? 637 LEU B CB  1 
ATOM   9102  C CG  . LEU B 1 637 ? 127.033 124.816 148.371 1.00 68.45  ? 637 LEU B CG  1 
ATOM   9103  C CD1 . LEU B 1 637 ? 127.622 125.430 149.637 1.00 65.09  ? 637 LEU B CD1 1 
ATOM   9104  C CD2 . LEU B 1 637 ? 125.766 125.588 148.024 1.00 65.47  ? 637 LEU B CD2 1 
ATOM   9105  N N   . LEU B 1 638 ? 129.742 123.829 144.643 1.00 67.72  ? 638 LEU B N   1 
ATOM   9106  C CA  . LEU B 1 638 ? 130.654 124.001 143.517 1.00 61.59  ? 638 LEU B CA  1 
ATOM   9107  C C   . LEU B 1 638 ? 130.036 123.518 142.192 1.00 62.02  ? 638 LEU B C   1 
ATOM   9108  O O   . LEU B 1 638 ? 130.052 124.254 141.213 1.00 63.36  ? 638 LEU B O   1 
ATOM   9109  C CB  . LEU B 1 638 ? 131.949 123.274 143.906 1.00 62.84  ? 638 LEU B CB  1 
ATOM   9110  C CG  . LEU B 1 638 ? 133.143 123.366 142.958 1.00 65.56  ? 638 LEU B CG  1 
ATOM   9111  C CD1 . LEU B 1 638 ? 133.610 124.804 142.775 1.00 62.24  ? 638 LEU B CD1 1 
ATOM   9112  C CD2 . LEU B 1 638 ? 134.275 122.552 143.577 1.00 64.21  ? 638 LEU B CD2 1 
ATOM   9113  N N   . ASN B 1 639 ? 129.389 122.349 142.173 1.00 73.09  ? 639 ASN B N   1 
ATOM   9114  C CA  . ASN B 1 639 ? 128.573 121.879 141.049 1.00 63.16  ? 639 ASN B CA  1 
ATOM   9115  C C   . ASN B 1 639 ? 127.424 122.844 140.726 1.00 64.07  ? 639 ASN B C   1 
ATOM   9116  O O   . ASN B 1 639 ? 127.164 123.111 139.559 1.00 75.44  ? 639 ASN B O   1 
ATOM   9117  C CB  . ASN B 1 639 ? 127.967 120.496 141.350 1.00 57.18  ? 639 ASN B CB  1 
ATOM   9118  C CG  . ASN B 1 639 ? 128.927 119.324 141.419 1.00 66.19  ? 639 ASN B CG  1 
ATOM   9119  O OD1 . ASN B 1 639 ? 130.072 119.381 141.022 1.00 68.69  ? 639 ASN B OD1 1 
ATOM   9120  N ND2 . ASN B 1 639 ? 128.481 118.199 141.922 1.00 68.68  ? 639 ASN B ND2 1 
ATOM   9121  N N   . MET B 1 640 ? 126.730 123.375 141.733 1.00 59.81  ? 640 MET B N   1 
ATOM   9122  C CA  . MET B 1 640 ? 125.598 124.284 141.567 1.00 59.69  ? 640 MET B CA  1 
ATOM   9123  C C   . MET B 1 640 ? 126.007 125.634 140.971 1.00 68.16  ? 640 MET B C   1 
ATOM   9124  O O   . MET B 1 640 ? 125.410 126.057 139.990 1.00 70.22  ? 640 MET B O   1 
ATOM   9125  C CB  . MET B 1 640 ? 124.883 124.426 142.916 1.00 65.54  ? 640 MET B CB  1 
ATOM   9126  C CG  . MET B 1 640 ? 123.617 125.286 142.872 1.00 69.39  ? 640 MET B CG  1 
ATOM   9127  S SD  . MET B 1 640 ? 123.781 127.036 143.287 1.00 82.07  ? 640 MET B SD  1 
ATOM   9128  C CE  . MET B 1 640 ? 124.215 126.949 145.040 1.00 66.57  ? 640 MET B CE  1 
ATOM   9129  N N   . LEU B 1 641 ? 127.069 126.273 141.468 1.00 72.65  ? 641 LEU B N   1 
ATOM   9130  C CA  . LEU B 1 641 ? 127.583 127.531 140.915 1.00 64.10  ? 641 LEU B CA  1 
ATOM   9131  C C   . LEU B 1 641 ? 128.075 127.356 139.478 1.00 61.28  ? 641 LEU B C   1 
ATOM   9132  O O   . LEU B 1 641 ? 127.751 128.164 138.616 1.00 69.04  ? 641 LEU B O   1 
ATOM   9133  C CB  . LEU B 1 641 ? 128.709 128.072 141.813 1.00 70.89  ? 641 LEU B CB  1 
ATOM   9134  C CG  . LEU B 1 641 ? 128.249 129.136 142.824 1.00 72.69  ? 641 LEU B CG  1 
ATOM   9135  C CD1 . LEU B 1 641 ? 127.139 128.676 143.759 1.00 63.71  ? 641 LEU B CD1 1 
ATOM   9136  C CD2 . LEU B 1 641 ? 129.437 129.547 143.688 1.00 73.43  ? 641 LEU B CD2 1 
ATOM   9137  N N   . ILE B 1 642 ? 128.825 126.300 139.184 1.00 67.07  ? 642 ILE B N   1 
ATOM   9138  C CA  . ILE B 1 642 ? 129.321 126.027 137.830 1.00 67.49  ? 642 ILE B CA  1 
ATOM   9139  C C   . ILE B 1 642 ? 128.190 125.671 136.863 1.00 67.35  ? 642 ILE B C   1 
ATOM   9140  O O   . ILE B 1 642 ? 128.205 126.140 135.727 1.00 76.05  ? 642 ILE B O   1 
ATOM   9141  C CB  . ILE B 1 642 ? 130.446 124.977 137.908 1.00 68.91  ? 642 ILE B CB  1 
ATOM   9142  C CG1 . ILE B 1 642 ? 131.724 125.688 138.411 1.00 66.91  ? 642 ILE B CG1 1 
ATOM   9143  C CG2 . ILE B 1 642 ? 130.707 124.299 136.563 1.00 65.81  ? 642 ILE B CG2 1 
ATOM   9144  C CD1 . ILE B 1 642 ? 132.801 124.757 138.955 1.00 67.10  ? 642 ILE B CD1 1 
ATOM   9145  N N   . ALA B 1 643 ? 127.167 124.922 137.285 1.00 65.94  ? 643 ALA B N   1 
ATOM   9146  C CA  . ALA B 1 643 ? 125.968 124.684 136.485 1.00 61.18  ? 643 ALA B CA  1 
ATOM   9147  C C   . ALA B 1 643 ? 125.243 125.998 136.146 1.00 70.60  ? 643 ALA B C   1 
ATOM   9148  O O   . ALA B 1 643 ? 124.972 126.248 134.974 1.00 80.51  ? 643 ALA B O   1 
ATOM   9149  C CB  . ALA B 1 643 ? 125.060 123.699 137.218 1.00 57.77  ? 643 ALA B CB  1 
ATOM   9150  N N   . LEU B 1 644 ? 125.013 126.880 137.122 1.00 78.52  ? 644 LEU B N   1 
ATOM   9151  C CA  . LEU B 1 644 ? 124.424 128.204 136.906 1.00 69.82  ? 644 LEU B CA  1 
ATOM   9152  C C   . LEU B 1 644 ? 125.260 129.075 135.964 1.00 69.75  ? 644 LEU B C   1 
ATOM   9153  O O   . LEU B 1 644 ? 124.699 129.649 135.036 1.00 82.17  ? 644 LEU B O   1 
ATOM   9154  C CB  . LEU B 1 644 ? 124.232 128.914 138.254 1.00 72.86  ? 644 LEU B CB  1 
ATOM   9155  C CG  . LEU B 1 644 ? 122.817 128.802 138.838 1.00 77.22  ? 644 LEU B CG  1 
ATOM   9156  C CD1 . LEU B 1 644 ? 122.309 127.374 138.997 1.00 78.40  ? 644 LEU B CD1 1 
ATOM   9157  C CD2 . LEU B 1 644 ? 122.816 129.445 140.216 1.00 78.76  ? 644 LEU B CD2 1 
ATOM   9158  N N   . MET B 1 645 ? 126.581 129.164 136.133 1.00 72.92  ? 645 MET B N   1 
ATOM   9159  C CA  . MET B 1 645 ? 127.443 129.891 135.190 1.00 76.95  ? 645 MET B CA  1 
ATOM   9160  C C   . MET B 1 645 ? 127.329 129.337 133.773 1.00 81.17  ? 645 MET B C   1 
ATOM   9161  O O   . MET B 1 645 ? 127.199 130.105 132.831 1.00 83.06  ? 645 MET B O   1 
ATOM   9162  C CB  . MET B 1 645 ? 128.909 129.833 135.619 1.00 74.40  ? 645 MET B CB  1 
ATOM   9163  C CG  . MET B 1 645 ? 129.184 130.637 136.883 1.00 81.85  ? 645 MET B CG  1 
ATOM   9164  S SD  . MET B 1 645 ? 130.878 130.446 137.467 1.00 94.00  ? 645 MET B SD  1 
ATOM   9165  C CE  . MET B 1 645 ? 130.632 131.065 139.148 1.00 82.05  ? 645 MET B CE  1 
ATOM   9166  N N   . SER B 1 646 ? 127.328 128.016 133.603 1.00 81.89  ? 646 SER B N   1 
ATOM   9167  C CA  . SER B 1 646 ? 127.257 127.404 132.276 1.00 81.03  ? 646 SER B CA  1 
ATOM   9168  C C   . SER B 1 646 ? 125.987 127.775 131.493 1.00 85.15  ? 646 SER B C   1 
ATOM   9169  O O   . SER B 1 646 ? 126.071 127.978 130.284 1.00 87.16  ? 646 SER B O   1 
ATOM   9170  C CB  . SER B 1 646 ? 127.429 125.888 132.383 1.00 76.66  ? 646 SER B CB  1 
ATOM   9171  O OG  . SER B 1 646 ? 126.249 125.232 132.808 1.00 78.96  ? 646 SER B OG  1 
ATOM   9172  N N   . GLU B 1 647 ? 124.822 127.919 132.139 1.00 90.30  ? 647 GLU B N   1 
ATOM   9173  C CA  . GLU B 1 647 ? 123.601 128.354 131.446 1.00 92.76  ? 647 GLU B CA  1 
ATOM   9174  C C   . GLU B 1 647 ? 123.475 129.881 131.338 1.00 94.62  ? 647 GLU B C   1 
ATOM   9175  O O   . GLU B 1 647 ? 123.046 130.387 130.304 1.00 99.01  ? 647 GLU B O   1 
ATOM   9176  C CB  . GLU B 1 647 ? 122.353 127.724 132.088 1.00 92.30  ? 647 GLU B CB  1 
ATOM   9177  C CG  . GLU B 1 647 ? 121.087 128.045 131.257 1.00 101.30 ? 647 GLU B CG  1 
ATOM   9178  C CD  . GLU B 1 647 ? 119.890 127.100 131.471 1.00 103.04 ? 647 GLU B CD  1 
ATOM   9179  O OE1 . GLU B 1 647 ? 120.055 125.975 131.986 1.00 98.81  ? 647 GLU B OE1 1 
ATOM   9180  O OE2 . GLU B 1 647 ? 118.743 127.471 131.146 1.00 99.26  ? 647 GLU B OE2 1 
ATOM   9181  N N   . THR B 1 648 ? 123.837 130.629 132.379 1.00 78.23  ? 648 THR B N   1 
ATOM   9182  C CA  . THR B 1 648 ? 123.577 132.079 132.462 1.00 80.26  ? 648 THR B CA  1 
ATOM   9183  C C   . THR B 1 648 ? 124.692 132.979 131.913 1.00 80.71  ? 648 THR B C   1 
ATOM   9184  O O   . THR B 1 648 ? 124.414 134.124 131.571 1.00 81.80  ? 648 THR B O   1 
ATOM   9185  C CB  . THR B 1 648 ? 123.243 132.508 133.897 1.00 78.59  ? 648 THR B CB  1 
ATOM   9186  O OG1 . THR B 1 648 ? 124.319 132.252 134.755 1.00 81.80  ? 648 THR B OG1 1 
ATOM   9187  C CG2 . THR B 1 648 ? 122.011 131.822 134.477 1.00 75.32  ? 648 THR B CG2 1 
ATOM   9188  N N   . VAL B 1 649 ? 125.937 132.509 131.793 1.00 82.30  ? 649 VAL B N   1 
ATOM   9189  C CA  . VAL B 1 649 ? 127.053 133.311 131.215 1.00 83.41  ? 649 VAL B CA  1 
ATOM   9190  C C   . VAL B 1 649 ? 127.212 132.819 129.782 1.00 87.67  ? 649 VAL B C   1 
ATOM   9191  O O   . VAL B 1 649 ? 128.198 132.107 129.503 1.00 87.26  ? 649 VAL B O   1 
ATOM   9192  C CB  . VAL B 1 649 ? 128.352 133.154 132.029 1.00 79.62  ? 649 VAL B CB  1 
ATOM   9193  C CG1 . VAL B 1 649 ? 129.441 134.097 131.538 1.00 79.31  ? 649 VAL B CG1 1 
ATOM   9194  C CG2 . VAL B 1 649 ? 128.107 133.354 133.517 1.00 80.95  ? 649 VAL B CG2 1 
ATOM   9195  N N   . ASN B 1 650 ? 126.263 133.174 128.918 1.00 90.51  ? 650 ASN B N   1 
ATOM   9196  C CA  . ASN B 1 650 ? 126.287 132.607 127.546 1.00 87.40  ? 650 ASN B CA  1 
ATOM   9197  C C   . ASN B 1 650 ? 126.698 133.650 126.504 1.00 86.89  ? 650 ASN B C   1 
ATOM   9198  O O   . ASN B 1 650 ? 126.867 133.224 125.344 1.00 84.00  ? 650 ASN B O   1 
ATOM   9199  C CB  . ASN B 1 650 ? 124.933 131.991 127.186 1.00 90.41  ? 650 ASN B CB  1 
ATOM   9200  C CG  . ASN B 1 650 ? 123.777 132.939 127.430 1.00 94.30  ? 650 ASN B CG  1 
ATOM   9201  O OD1 . ASN B 1 650 ? 123.980 134.137 127.615 1.00 97.53  ? 650 ASN B OD1 1 
ATOM   9202  N ND2 . ASN B 1 650 ? 122.564 132.413 127.431 1.00 89.13  ? 650 ASN B ND2 1 
ATOM   9203  N N   . HIS B 1 651 ? 126.824 134.929 126.838 1.00 92.25  ? 651 HIS B N   1 
ATOM   9204  C CA  . HIS B 1 651 ? 127.127 135.986 125.830 1.00 93.13  ? 651 HIS B CA  1 
ATOM   9205  C C   . HIS B 1 651 ? 125.887 136.499 125.092 1.00 93.03  ? 651 HIS B C   1 
ATOM   9206  O O   . HIS B 1 651 ? 126.049 137.450 124.331 1.00 88.40  ? 651 HIS B O   1 
ATOM   9207  C CB  . HIS B 1 651 ? 128.292 135.540 124.940 1.00 91.15  ? 651 HIS B CB  1 
ATOM   9208  C CG  . HIS B 1 651 ? 129.537 135.242 125.704 1.00 91.91  ? 651 HIS B CG  1 
ATOM   9209  N ND1 . HIS B 1 651 ? 130.084 136.131 126.600 1.00 90.52  ? 651 HIS B ND1 1 
ATOM   9210  C CD2 . HIS B 1 651 ? 130.341 134.160 125.712 1.00 92.65  ? 651 HIS B CD2 1 
ATOM   9211  C CE1 . HIS B 1 651 ? 131.165 135.604 127.132 1.00 90.40  ? 651 HIS B CE1 1 
ATOM   9212  N NE2 . HIS B 1 651 ? 131.345 134.399 126.603 1.00 87.23  ? 651 HIS B NE2 1 
ATOM   9213  N N   . VAL B 1 652 ? 124.705 135.911 125.300 1.00 102.31 ? 652 VAL B N   1 
ATOM   9214  C CA  . VAL B 1 652 ? 123.479 136.471 124.717 1.00 98.34  ? 652 VAL B CA  1 
ATOM   9215  C C   . VAL B 1 652 ? 123.437 137.972 125.028 1.00 99.19  ? 652 VAL B C   1 
ATOM   9216  O O   . VAL B 1 652 ? 123.698 138.378 126.159 1.00 98.23  ? 652 VAL B O   1 
ATOM   9217  C CB  . VAL B 1 652 ? 122.235 135.739 125.251 1.00 96.77  ? 652 VAL B CB  1 
ATOM   9218  C CG1 . VAL B 1 652 ? 120.926 136.383 124.781 1.00 97.31  ? 652 VAL B CG1 1 
ATOM   9219  C CG2 . VAL B 1 652 ? 122.211 134.285 124.774 1.00 96.64  ? 652 VAL B CG2 1 
ATOM   9220  N N   . ALA B 1 653 ? 123.143 138.810 124.033 1.00 108.54 ? 653 ALA B N   1 
ATOM   9221  C CA  . ALA B 1 653 ? 123.089 140.260 124.208 1.00 108.60 ? 653 ALA B CA  1 
ATOM   9222  C C   . ALA B 1 653 ? 121.970 140.656 125.184 1.00 107.17 ? 653 ALA B C   1 
ATOM   9223  O O   . ALA B 1 653 ? 120.884 140.080 125.155 1.00 105.39 ? 653 ALA B O   1 
ATOM   9224  C CB  . ALA B 1 653 ? 122.918 140.916 122.836 1.00 106.05 ? 653 ALA B CB  1 
ATOM   9225  N N   . ASP B 1 654 ? 122.224 141.624 126.062 1.00 106.66 ? 654 ASP B N   1 
ATOM   9226  C CA  . ASP B 1 654 ? 121.367 141.867 127.223 1.00 105.79 ? 654 ASP B CA  1 
ATOM   9227  C C   . ASP B 1 654 ? 119.951 142.348 126.835 1.00 106.70 ? 654 ASP B C   1 
ATOM   9228  O O   . ASP B 1 654 ? 119.777 143.423 126.260 1.00 100.92 ? 654 ASP B O   1 
ATOM   9229  C CB  . ASP B 1 654 ? 122.067 142.849 128.174 1.00 106.60 ? 654 ASP B CB  1 
ATOM   9230  C CG  . ASP B 1 654 ? 121.336 143.006 129.513 1.00 109.56 ? 654 ASP B CG  1 
ATOM   9231  O OD1 . ASP B 1 654 ? 120.388 142.240 129.787 1.00 108.24 ? 654 ASP B OD1 1 
ATOM   9232  O OD2 . ASP B 1 654 ? 121.674 143.927 130.286 1.00 107.00 ? 654 ASP B OD2 1 
ATOM   9233  N N   . ASN B 1 655 ? 118.918 141.566 127.192 1.00 104.95 ? 655 ASN B N   1 
ATOM   9234  C CA  . ASN B 1 655 ? 117.512 141.904 126.802 1.00 102.07 ? 655 ASN B CA  1 
ATOM   9235  C C   . ASN B 1 655 ? 116.757 142.561 127.965 1.00 104.20 ? 655 ASN B C   1 
ATOM   9236  O O   . ASN B 1 655 ? 115.518 142.430 128.000 1.00 105.89 ? 655 ASN B O   1 
ATOM   9237  C CB  . ASN B 1 655 ? 116.759 140.674 126.287 1.00 101.08 ? 655 ASN B CB  1 
ATOM   9238  C CG  . ASN B 1 655 ? 117.359 140.100 125.021 1.00 109.41 ? 655 ASN B CG  1 
ATOM   9239  O OD1 . ASN B 1 655 ? 116.967 139.023 124.576 1.00 109.61 ? 655 ASN B OD1 1 
ATOM   9240  N ND2 . ASN B 1 655 ? 118.309 140.809 124.434 1.00 110.97 ? 655 ASN B ND2 1 
ATOM   9241  N N   . SER B 1 656 ? 117.460 143.247 128.865 1.00 95.66  ? 656 SER B N   1 
ATOM   9242  C CA  . SER B 1 656 ? 116.884 143.939 130.016 1.00 89.24  ? 656 SER B CA  1 
ATOM   9243  C C   . SER B 1 656 ? 116.192 145.268 129.718 1.00 90.27  ? 656 SER B C   1 
ATOM   9244  O O   . SER B 1 656 ? 115.146 145.524 130.306 1.00 95.03  ? 656 SER B O   1 
ATOM   9245  C CB  . SER B 1 656 ? 117.951 144.156 131.086 1.00 93.22  ? 656 SER B CB  1 
ATOM   9246  O OG  . SER B 1 656 ? 118.980 144.962 130.564 1.00 98.66  ? 656 SER B OG  1 
ATOM   9247  N N   . TRP B 1 657 ? 116.677 146.084 128.782 1.00 82.07  ? 657 TRP B N   1 
ATOM   9248  C CA  . TRP B 1 657 ? 115.993 147.323 128.376 1.00 85.23  ? 657 TRP B CA  1 
ATOM   9249  C C   . TRP B 1 657 ? 114.581 147.065 127.846 1.00 84.90  ? 657 TRP B C   1 
ATOM   9250  O O   . TRP B 1 657 ? 113.628 147.747 128.204 1.00 89.28  ? 657 TRP B O   1 
ATOM   9251  C CB  . TRP B 1 657 ? 116.853 148.061 127.348 1.00 81.06  ? 657 TRP B CB  1 
ATOM   9252  C CG  . TRP B 1 657 ? 116.197 149.224 126.669 1.00 84.50  ? 657 TRP B CG  1 
ATOM   9253  C CD1 . TRP B 1 657 ? 116.147 150.493 127.132 1.00 85.70  ? 657 TRP B CD1 1 
ATOM   9254  C CD2 . TRP B 1 657 ? 115.482 149.245 125.397 1.00 90.69  ? 657 TRP B CD2 1 
ATOM   9255  N NE1 . TRP B 1 657 ? 115.444 151.287 126.251 1.00 84.29  ? 657 TRP B NE1 1 
ATOM   9256  C CE2 . TRP B 1 657 ? 115.011 150.569 125.161 1.00 90.65  ? 657 TRP B CE2 1 
ATOM   9257  C CE3 . TRP B 1 657 ? 115.220 148.283 124.398 1.00 88.55  ? 657 TRP B CE3 1 
ATOM   9258  C CZ2 . TRP B 1 657 ? 114.300 150.914 124.004 1.00 85.72  ? 657 TRP B CZ2 1 
ATOM   9259  C CZ3 . TRP B 1 657 ? 114.508 148.621 123.236 1.00 85.60  ? 657 TRP B CZ3 1 
ATOM   9260  C CH2 . TRP B 1 657 ? 114.039 149.931 123.038 1.00 82.60  ? 657 TRP B CH2 1 
ATOM   9261  N N   . SER B 1 658 ? 114.416 146.015 127.052 1.00 77.42  ? 658 SER B N   1 
ATOM   9262  C CA  . SER B 1 658 ? 113.127 145.628 126.464 1.00 69.87  ? 658 SER B CA  1 
ATOM   9263  C C   . SER B 1 658 ? 112.193 144.949 127.468 1.00 76.28  ? 658 SER B C   1 
ATOM   9264  O O   . SER B 1 658 ? 110.983 145.137 127.405 1.00 83.36  ? 658 SER B O   1 
ATOM   9265  C CB  . SER B 1 658 ? 113.347 144.773 125.217 1.00 70.74  ? 658 SER B CB  1 
ATOM   9266  O OG  . SER B 1 658 ? 113.821 143.481 125.531 1.00 80.87  ? 658 SER B OG  1 
ATOM   9267  N N   . ILE B 1 659 ? 112.716 144.164 128.405 1.00 69.80  ? 659 ILE B N   1 
ATOM   9268  C CA  . ILE B 1 659 ? 111.894 143.594 129.478 1.00 67.00  ? 659 ILE B CA  1 
ATOM   9269  C C   . ILE B 1 659 ? 111.444 144.714 130.424 1.00 66.86  ? 659 ILE B C   1 
ATOM   9270  O O   . ILE B 1 659 ? 110.297 144.725 130.855 1.00 75.38  ? 659 ILE B O   1 
ATOM   9271  C CB  . ILE B 1 659 ? 112.638 142.439 130.168 1.00 69.70  ? 659 ILE B CB  1 
ATOM   9272  C CG1 . ILE B 1 659 ? 112.829 141.252 129.213 1.00 70.18  ? 659 ILE B CG1 1 
ATOM   9273  C CG2 . ILE B 1 659 ? 111.895 141.986 131.434 1.00 71.87  ? 659 ILE B CG2 1 
ATOM   9274  C CD1 . ILE B 1 659 ? 113.810 140.198 129.719 1.00 69.77  ? 659 ILE B CD1 1 
ATOM   9275  N N   . TRP B 1 660 ? 112.270 145.730 130.665 1.00 57.69  ? 660 TRP B N   1 
ATOM   9276  C CA  . TRP B 1 660 ? 111.857 146.942 131.364 1.00 62.85  ? 660 TRP B CA  1 
ATOM   9277  C C   . TRP B 1 660 ? 110.798 147.747 130.601 1.00 66.83  ? 660 TRP B C   1 
ATOM   9278  O O   . TRP B 1 660 ? 109.799 148.152 131.186 1.00 76.34  ? 660 TRP B O   1 
ATOM   9279  C CB  . TRP B 1 660 ? 113.089 147.779 131.684 1.00 66.34  ? 660 TRP B CB  1 
ATOM   9280  C CG  . TRP B 1 660 ? 112.778 149.140 132.200 1.00 65.92  ? 660 TRP B CG  1 
ATOM   9281  C CD1 . TRP B 1 660 ? 112.114 149.411 133.341 1.00 62.83  ? 660 TRP B CD1 1 
ATOM   9282  C CD2 . TRP B 1 660 ? 113.023 150.425 131.563 1.00 64.71  ? 660 TRP B CD2 1 
ATOM   9283  N NE1 . TRP B 1 660 ? 111.957 150.772 133.467 1.00 55.94  ? 660 TRP B NE1 1 
ATOM   9284  C CE2 . TRP B 1 660 ? 112.510 151.446 132.407 1.00 63.10  ? 660 TRP B CE2 1 
ATOM   9285  C CE3 . TRP B 1 660 ? 113.618 150.826 130.353 1.00 69.52  ? 660 TRP B CE3 1 
ATOM   9286  C CZ2 . TRP B 1 660 ? 112.610 152.804 132.084 1.00 67.17  ? 660 TRP B CZ2 1 
ATOM   9287  C CZ3 . TRP B 1 660 ? 113.709 152.182 130.009 1.00 70.23  ? 660 TRP B CZ3 1 
ATOM   9288  C CH2 . TRP B 1 660 ? 113.214 153.170 130.873 1.00 68.36  ? 660 TRP B CH2 1 
ATOM   9289  N N   . LYS B 1 661 ? 110.917 147.918 129.283 1.00 67.28  ? 661 LYS B N   1 
ATOM   9290  C CA  . LYS B 1 661 ? 109.862 148.518 128.449 1.00 60.71  ? 661 LYS B CA  1 
ATOM   9291  C C   . LYS B 1 661 ? 108.537 147.762 128.539 1.00 62.82  ? 661 LYS B C   1 
ATOM   9292  O O   . LYS B 1 661 ? 107.492 148.396 128.583 1.00 65.99  ? 661 LYS B O   1 
ATOM   9293  C CB  . LYS B 1 661 ? 110.338 148.590 126.995 1.00 58.01  ? 661 LYS B CB  1 
ATOM   9294  C CG  . LYS B 1 661 ? 111.333 149.728 126.739 1.00 62.18  ? 661 LYS B CG  1 
ATOM   9295  C CD  . LYS B 1 661 ? 110.603 151.028 126.397 1.00 70.03  ? 661 LYS B CD  1 
ATOM   9296  C CE  . LYS B 1 661 ? 111.607 152.125 126.048 1.00 74.58  ? 661 LYS B CE  1 
ATOM   9297  N NZ  . LYS B 1 661 ? 110.954 153.266 125.358 1.00 67.90  ? 661 LYS B NZ  1 
ATOM   9298  N N   . LEU B 1 662 ? 108.538 146.433 128.641 1.00 58.00  ? 662 LEU B N   1 
ATOM   9299  C CA  . LEU B 1 662 ? 107.328 145.646 128.895 1.00 52.44  ? 662 LEU B CA  1 
ATOM   9300  C C   . LEU B 1 662 ? 106.771 145.856 130.306 1.00 68.79  ? 662 LEU B C   1 
ATOM   9301  O O   . LEU B 1 662 ? 105.563 145.988 130.465 1.00 78.01  ? 662 LEU B O   1 
ATOM   9302  C CB  . LEU B 1 662 ? 107.627 144.170 128.593 1.00 52.82  ? 662 LEU B CB  1 
ATOM   9303  C CG  . LEU B 1 662 ? 106.454 143.206 128.829 1.00 58.93  ? 662 LEU B CG  1 
ATOM   9304  C CD1 . LEU B 1 662 ? 105.301 143.413 127.857 1.00 62.25  ? 662 LEU B CD1 1 
ATOM   9305  C CD2 . LEU B 1 662 ? 106.949 141.780 128.671 1.00 62.21  ? 662 LEU B CD2 1 
ATOM   9306  N N   . GLN B 1 663 ? 107.610 145.958 131.335 1.00 62.30  ? 663 GLN B N   1 
ATOM   9307  C CA  . GLN B 1 663 ? 107.167 146.302 132.686 1.00 44.14  ? 663 GLN B CA  1 
ATOM   9308  C C   . GLN B 1 663 ? 106.482 147.670 132.726 1.00 59.13  ? 663 GLN B C   1 
ATOM   9309  O O   . GLN B 1 663 ? 105.414 147.805 133.319 1.00 62.72  ? 663 GLN B O   1 
ATOM   9310  C CB  . GLN B 1 663 ? 108.356 146.272 133.646 1.00 49.05  ? 663 GLN B CB  1 
ATOM   9311  C CG  . GLN B 1 663 ? 108.802 144.841 133.947 1.00 57.74  ? 663 GLN B CG  1 
ATOM   9312  C CD  . GLN B 1 663 ? 110.020 144.781 134.848 1.00 63.94  ? 663 GLN B CD  1 
ATOM   9313  O OE1 . GLN B 1 663 ? 110.671 145.769 135.147 1.00 58.64  ? 663 GLN B OE1 1 
ATOM   9314  N NE2 . GLN B 1 663 ? 110.364 143.612 135.331 1.00 64.63  ? 663 GLN B NE2 1 
ATOM   9315  N N   . LYS B 1 664 ? 107.038 148.675 132.037 1.00 68.27  ? 664 LYS B N   1 
ATOM   9316  C CA  . LYS B 1 664 ? 106.393 149.982 131.862 1.00 55.97  ? 664 LYS B CA  1 
ATOM   9317  C C   . LYS B 1 664 ? 105.108 149.922 131.038 1.00 61.79  ? 664 LYS B C   1 
ATOM   9318  O O   . LYS B 1 664 ? 104.157 150.600 131.394 1.00 72.47  ? 664 LYS B O   1 
ATOM   9319  C CB  . LYS B 1 664 ? 107.369 150.989 131.260 1.00 53.05  ? 664 LYS B CB  1 
ATOM   9320  C CG  . LYS B 1 664 ? 108.538 151.276 132.204 1.00 56.41  ? 664 LYS B CG  1 
ATOM   9321  C CD  . LYS B 1 664 ? 109.087 152.687 132.008 1.00 61.18  ? 664 LYS B CD  1 
ATOM   9322  C CE  . LYS B 1 664 ? 109.597 152.922 130.584 1.00 64.10  ? 664 LYS B CE  1 
ATOM   9323  N NZ  . LYS B 1 664 ? 110.013 154.335 130.394 1.00 69.07  ? 664 LYS B NZ  1 
ATOM   9324  N N   . ALA B 1 665 ? 105.021 149.083 130.007 1.00 48.59  ? 665 ALA B N   1 
ATOM   9325  C CA  . ALA B 1 665 ? 103.784 148.845 129.267 1.00 45.38  ? 665 ALA B CA  1 
ATOM   9326  C C   . ALA B 1 665 ? 102.673 148.255 130.141 1.00 57.27  ? 665 ALA B C   1 
ATOM   9327  O O   . ALA B 1 665 ? 101.569 148.779 130.159 1.00 68.67  ? 665 ALA B O   1 
ATOM   9328  C CB  . ALA B 1 665 ? 104.075 147.936 128.076 1.00 55.42  ? 665 ALA B CB  1 
ATOM   9329  N N   . ILE B 1 666 ? 102.952 147.212 130.920 1.00 66.86  ? 666 ILE B N   1 
ATOM   9330  C CA  . ILE B 1 666 ? 101.986 146.604 131.849 1.00 59.79  ? 666 ILE B CA  1 
ATOM   9331  C C   . ILE B 1 666 ? 101.514 147.624 132.895 1.00 58.29  ? 666 ILE B C   1 
ATOM   9332  O O   . ILE B 1 666 ? 100.325 147.722 133.183 1.00 65.58  ? 666 ILE B O   1 
ATOM   9333  C CB  . ILE B 1 666 ? 102.620 145.359 132.502 1.00 58.52  ? 666 ILE B CB  1 
ATOM   9334  C CG1 . ILE B 1 666 ? 102.822 144.238 131.467 1.00 52.13  ? 666 ILE B CG1 1 
ATOM   9335  C CG2 . ILE B 1 666 ? 101.767 144.831 133.660 1.00 66.01  ? 666 ILE B CG2 1 
ATOM   9336  C CD1 . ILE B 1 666 ? 103.862 143.206 131.892 1.00 58.65  ? 666 ILE B CD1 1 
ATOM   9337  N N   . SER B 1 667 ? 102.438 148.427 133.426 1.00 58.63  ? 667 SER B N   1 
ATOM   9338  C CA  . SER B 1 667 ? 102.157 149.511 134.371 1.00 57.19  ? 667 SER B CA  1 
ATOM   9339  C C   . SER B 1 667 ? 101.230 150.574 133.782 1.00 55.40  ? 667 SER B C   1 
ATOM   9340  O O   . SER B 1 667 ? 100.209 150.902 134.379 1.00 58.75  ? 667 SER B O   1 
ATOM   9341  C CB  . SER B 1 667 ? 103.486 150.123 134.805 1.00 61.39  ? 667 SER B CB  1 
ATOM   9342  O OG  . SER B 1 667 ? 103.277 151.212 135.663 1.00 63.85  ? 667 SER B OG  1 
ATOM   9343  N N   . VAL B 1 668 ? 101.517 151.062 132.572 1.00 65.67  ? 668 VAL B N   1 
ATOM   9344  C CA  . VAL B 1 668 ? 100.680 152.013 131.825 1.00 65.53  ? 668 VAL B CA  1 
ATOM   9345  C C   . VAL B 1 668 ? 99.269  151.490 131.615 1.00 70.24  ? 668 VAL B C   1 
ATOM   9346  O O   . VAL B 1 668 ? 98.309  152.181 131.937 1.00 78.72  ? 668 VAL B O   1 
ATOM   9347  C CB  . VAL B 1 668 ? 101.343 152.326 130.474 1.00 59.88  ? 668 VAL B CB  1 
ATOM   9348  C CG1 . VAL B 1 668 ? 100.410 152.877 129.402 1.00 67.15  ? 668 VAL B CG1 1 
ATOM   9349  C CG2 . VAL B 1 668 ? 102.440 153.356 130.686 1.00 62.97  ? 668 VAL B CG2 1 
ATOM   9350  N N   . LEU B 1 669 ? 99.129  150.278 131.089 1.00 63.77  ? 669 LEU B N   1 
ATOM   9351  C CA  . LEU B 1 669 ? 97.829  149.735 130.715 1.00 60.14  ? 669 LEU B CA  1 
ATOM   9352  C C   . LEU B 1 669 ? 96.941  149.463 131.929 1.00 65.98  ? 669 LEU B C   1 
ATOM   9353  O O   . LEU B 1 669 ? 95.722  149.466 131.800 1.00 75.49  ? 669 LEU B O   1 
ATOM   9354  C CB  . LEU B 1 669 ? 98.057  148.472 129.880 1.00 65.80  ? 669 LEU B CB  1 
ATOM   9355  C CG  . LEU B 1 669 ? 98.784  148.742 128.555 1.00 66.00  ? 669 LEU B CG  1 
ATOM   9356  C CD1 . LEU B 1 669 ? 99.334  147.439 128.004 1.00 66.40  ? 669 LEU B CD1 1 
ATOM   9357  C CD2 . LEU B 1 669 ? 97.853  149.362 127.529 1.00 63.71  ? 669 LEU B CD2 1 
ATOM   9358  N N   . GLU B 1 670 ? 97.521  149.274 133.110 1.00 79.19  ? 670 GLU B N   1 
ATOM   9359  C CA  . GLU B 1 670 ? 96.808  149.289 134.384 1.00 77.84  ? 670 GLU B CA  1 
ATOM   9360  C C   . GLU B 1 670 ? 96.437  150.700 134.859 1.00 77.81  ? 670 GLU B C   1 
ATOM   9361  O O   . GLU B 1 670 ? 95.272  150.941 135.175 1.00 77.90  ? 670 GLU B O   1 
ATOM   9362  C CB  . GLU B 1 670 ? 97.651  148.563 135.438 1.00 73.17  ? 670 GLU B CB  1 
ATOM   9363  C CG  . GLU B 1 670 ? 97.480  147.048 135.329 1.00 79.06  ? 670 GLU B CG  1 
ATOM   9364  C CD  . GLU B 1 670 ? 96.022  146.646 135.575 1.00 89.64  ? 670 GLU B CD  1 
ATOM   9365  O OE1 . GLU B 1 670 ? 95.445  147.088 136.591 1.00 89.29  ? 670 GLU B OE1 1 
ATOM   9366  O OE2 . GLU B 1 670 ? 95.415  145.935 134.739 1.00 93.46  ? 670 GLU B OE2 1 
ATOM   9367  N N   . MET B 1 671 ? 97.374  151.649 134.854 1.00 70.39  ? 671 MET B N   1 
ATOM   9368  C CA  . MET B 1 671 ? 97.116  153.036 135.252 1.00 69.45  ? 671 MET B CA  1 
ATOM   9369  C C   . MET B 1 671 ? 96.058  153.749 134.413 1.00 67.77  ? 671 MET B C   1 
ATOM   9370  O O   . MET B 1 671 ? 95.328  154.584 134.939 1.00 79.28  ? 671 MET B O   1 
ATOM   9371  C CB  . MET B 1 671 ? 98.403  153.852 135.163 1.00 67.53  ? 671 MET B CB  1 
ATOM   9372  C CG  . MET B 1 671 ? 99.366  153.549 136.300 1.00 64.09  ? 671 MET B CG  1 
ATOM   9373  S SD  . MET B 1 671 ? 100.703 154.743 136.397 1.00 67.34  ? 671 MET B SD  1 
ATOM   9374  C CE  . MET B 1 671 ? 101.649 154.354 134.914 1.00 70.66  ? 671 MET B CE  1 
ATOM   9375  N N   . GLU B 1 672 ? 95.925  153.439 133.127 1.00 73.88  ? 672 GLU B N   1 
ATOM   9376  C CA  . GLU B 1 672 ? 94.906  154.040 132.260 1.00 76.45  ? 672 GLU B CA  1 
ATOM   9377  C C   . GLU B 1 672 ? 93.459  153.777 132.702 1.00 80.94  ? 672 GLU B C   1 
ATOM   9378  O O   . GLU B 1 672 ? 92.572  154.536 132.329 1.00 77.09  ? 672 GLU B O   1 
ATOM   9379  C CB  . GLU B 1 672 ? 95.079  153.516 130.834 1.00 75.01  ? 672 GLU B CB  1 
ATOM   9380  C CG  . GLU B 1 672 ? 96.188  154.240 130.070 1.00 77.20  ? 672 GLU B CG  1 
ATOM   9381  C CD  . GLU B 1 672 ? 96.147  153.832 128.597 1.00 85.84  ? 672 GLU B CD  1 
ATOM   9382  O OE1 . GLU B 1 672 ? 95.962  152.634 128.307 1.00 85.17  ? 672 GLU B OE1 1 
ATOM   9383  O OE2 . GLU B 1 672 ? 96.253  154.702 127.708 1.00 85.99  ? 672 GLU B OE2 1 
ATOM   9384  N N   . ASN B 1 673 ? 93.197  152.738 133.501 1.00 88.96  ? 673 ASN B N   1 
ATOM   9385  C CA  . ASN B 1 673 ? 91.866  152.465 134.056 1.00 86.04  ? 673 ASN B CA  1 
ATOM   9386  C C   . ASN B 1 673 ? 91.556  153.304 135.302 1.00 85.70  ? 673 ASN B C   1 
ATOM   9387  O O   . ASN B 1 673 ? 90.439  153.263 135.805 1.00 91.09  ? 673 ASN B O   1 
ATOM   9388  C CB  . ASN B 1 673 ? 91.718  150.972 134.378 1.00 88.08  ? 673 ASN B CB  1 
ATOM   9389  C CG  . ASN B 1 673 ? 92.195  150.084 133.257 1.00 86.53  ? 673 ASN B CG  1 
ATOM   9390  O OD1 . ASN B 1 673 ? 91.536  149.888 132.248 1.00 85.00  ? 673 ASN B OD1 1 
ATOM   9391  N ND2 . ASN B 1 673 ? 93.387  149.568 133.394 1.00 83.18  ? 673 ASN B ND2 1 
ATOM   9392  N N   . GLY B 1 674 ? 92.520  154.053 135.832 1.00 84.65  ? 674 GLY B N   1 
ATOM   9393  C CA  . GLY B 1 674 ? 92.390  154.724 137.117 1.00 83.46  ? 674 GLY B CA  1 
ATOM   9394  C C   . GLY B 1 674 ? 92.441  153.723 138.266 1.00 86.28  ? 674 GLY B C   1 
ATOM   9395  O O   . GLY B 1 674 ? 93.303  152.850 138.305 1.00 90.01  ? 674 GLY B O   1 
ATOM   9396  N N   . TYR B 1 675 ? 91.513  153.853 139.204 1.00 87.36  ? 675 TYR B N   1 
ATOM   9397  C CA  . TYR B 1 675 ? 91.443  153.052 140.424 1.00 88.28  ? 675 TYR B CA  1 
ATOM   9398  C C   . TYR B 1 675 ? 90.096  152.334 140.529 1.00 89.58  ? 675 TYR B C   1 
ATOM   9399  O O   . TYR B 1 675 ? 89.112  152.774 139.943 1.00 92.01  ? 675 TYR B O   1 
ATOM   9400  C CB  . TYR B 1 675 ? 91.658  153.955 141.640 1.00 86.22  ? 675 TYR B CB  1 
ATOM   9401  C CG  . TYR B 1 675 ? 92.898  154.833 141.638 1.00 88.03  ? 675 TYR B CG  1 
ATOM   9402  C CD1 . TYR B 1 675 ? 94.180  154.259 141.740 1.00 83.48  ? 675 TYR B CD1 1 
ATOM   9403  C CD2 . TYR B 1 675 ? 92.761  156.230 141.600 1.00 87.74  ? 675 TYR B CD2 1 
ATOM   9404  C CE1 . TYR B 1 675 ? 95.320  155.081 141.799 1.00 84.75  ? 675 TYR B CE1 1 
ATOM   9405  C CE2 . TYR B 1 675 ? 93.896  157.054 141.661 1.00 84.83  ? 675 TYR B CE2 1 
ATOM   9406  C CZ  . TYR B 1 675 ? 95.178  156.483 141.759 1.00 86.33  ? 675 TYR B CZ  1 
ATOM   9407  O OH  . TYR B 1 675 ? 96.260  157.299 141.817 1.00 86.61  ? 675 TYR B OH  1 
ATOM   9408  N N   . TRP B 1 676 ? 90.013  151.266 141.321 1.00 87.26  ? 676 TRP B N   1 
ATOM   9409  C CA  . TRP B 1 676 ? 88.793  150.458 141.479 1.00 84.73  ? 676 TRP B CA  1 
ATOM   9410  C C   . TRP B 1 676 ? 87.545  151.278 141.866 1.00 87.96  ? 676 TRP B C   1 
ATOM   9411  O O   . TRP B 1 676 ? 86.432  150.924 141.474 1.00 92.78  ? 676 TRP B O   1 
ATOM   9412  C CB  . TRP B 1 676 ? 89.080  149.359 142.512 1.00 84.47  ? 676 TRP B CB  1 
ATOM   9413  C CG  . TRP B 1 676 ? 89.345  149.817 143.916 1.00 90.74  ? 676 TRP B CG  1 
ATOM   9414  C CD1 . TRP B 1 676 ? 90.559  150.080 144.451 1.00 87.43  ? 676 TRP B CD1 1 
ATOM   9415  C CD2 . TRP B 1 676 ? 88.381  150.099 144.975 1.00 88.67  ? 676 TRP B CD2 1 
ATOM   9416  N NE1 . TRP B 1 676 ? 90.407  150.511 145.751 1.00 85.19  ? 676 TRP B NE1 1 
ATOM   9417  C CE2 . TRP B 1 676 ? 89.085  150.561 146.119 1.00 86.51  ? 676 TRP B CE2 1 
ATOM   9418  C CE3 . TRP B 1 676 ? 86.975  150.018 145.080 1.00 84.71  ? 676 TRP B CE3 1 
ATOM   9419  C CZ2 . TRP B 1 676 ? 88.434  150.949 147.296 1.00 85.81  ? 676 TRP B CZ2 1 
ATOM   9420  C CZ3 . TRP B 1 676 ? 86.310  150.404 146.257 1.00 87.19  ? 676 TRP B CZ3 1 
ATOM   9421  C CH2 . TRP B 1 676 ? 87.035  150.877 147.360 1.00 87.66  ? 676 TRP B CH2 1 
ATOM   9422  N N   . TRP B 1 677 ? 87.735  152.388 142.586 1.00 88.94  ? 677 TRP B N   1 
ATOM   9423  C CA  . TRP B 1 677 ? 86.722  153.345 143.050 1.00 90.93  ? 677 TRP B CA  1 
ATOM   9424  C C   . TRP B 1 677 ? 86.504  154.555 142.121 1.00 94.40  ? 677 TRP B C   1 
ATOM   9425  O O   . TRP B 1 677 ? 85.533  155.292 142.296 1.00 96.28  ? 677 TRP B O   1 
ATOM   9426  C CB  . TRP B 1 677 ? 87.170  153.836 144.434 1.00 88.68  ? 677 TRP B CB  1 
ATOM   9427  C CG  . TRP B 1 677 ? 88.481  154.566 144.467 1.00 85.07  ? 677 TRP B CG  1 
ATOM   9428  C CD1 . TRP B 1 677 ? 89.695  153.984 144.564 1.00 88.46  ? 677 TRP B CD1 1 
ATOM   9429  C CD2 . TRP B 1 677 ? 88.747  156.001 144.399 1.00 87.41  ? 677 TRP B CD2 1 
ATOM   9430  N NE1 . TRP B 1 677 ? 90.681  154.943 144.528 1.00 89.12  ? 677 TRP B NE1 1 
ATOM   9431  C CE2 . TRP B 1 677 ? 90.159  156.204 144.402 1.00 89.10  ? 677 TRP B CE2 1 
ATOM   9432  C CE3 . TRP B 1 677 ? 87.941  157.155 144.345 1.00 89.28  ? 677 TRP B CE3 1 
ATOM   9433  C CZ2 . TRP B 1 677 ? 90.744  157.472 144.304 1.00 88.06  ? 677 TRP B CZ2 1 
ATOM   9434  C CZ3 . TRP B 1 677 ? 88.516  158.438 144.249 1.00 92.34  ? 677 TRP B CZ3 1 
ATOM   9435  C CH2 . TRP B 1 677 ? 89.910  158.595 144.214 1.00 90.62  ? 677 TRP B CH2 1 
ATOM   9436  N N   . CYS B 1 678 ? 87.388  154.793 141.151 1.00 96.73  ? 678 CYS B N   1 
ATOM   9437  C CA  . CYS B 1 678 ? 87.396  155.966 140.269 1.00 96.26  ? 678 CYS B CA  1 
ATOM   9438  C C   . CYS B 1 678 ? 87.969  155.565 138.906 1.00 98.92  ? 678 CYS B C   1 
ATOM   9439  O O   . CYS B 1 678 ? 89.163  155.707 138.625 1.00 100.42 ? 678 CYS B O   1 
ATOM   9440  C CB  . CYS B 1 678 ? 88.174  157.109 140.931 1.00 99.90  ? 678 CYS B CB  1 
ATOM   9441  S SG  . CYS B 1 678 ? 88.239  158.569 139.851 1.00 101.59 ? 678 CYS B SG  1 
ATOM   9442  N N   . ARG B 1 679 ? 87.098  154.964 138.093 1.00 102.44 ? 679 ARG B N   1 
ATOM   9443  C CA  . ARG B 1 679 ? 87.446  154.308 136.828 1.00 99.87  ? 679 ARG B CA  1 
ATOM   9444  C C   . ARG B 1 679 ? 87.554  155.363 135.729 1.00 99.70  ? 679 ARG B C   1 
ATOM   9445  O O   . ARG B 1 679 ? 86.552  155.918 135.291 1.00 100.11 ? 679 ARG B O   1 
ATOM   9446  C CB  . ARG B 1 679 ? 86.437  153.181 136.536 1.00 98.28  ? 679 ARG B CB  1 
ATOM   9447  C CG  . ARG B 1 679 ? 86.489  152.123 137.657 1.00 99.48  ? 679 ARG B CG  1 
ATOM   9448  C CD  . ARG B 1 679 ? 85.410  151.045 137.551 1.00 101.77 ? 679 ARG B CD  1 
ATOM   9449  N NE  . ARG B 1 679 ? 85.282  150.327 138.835 1.00 106.47 ? 679 ARG B NE  1 
ATOM   9450  C CZ  . ARG B 1 679 ? 84.516  149.295 139.123 1.00 104.43 ? 679 ARG B CZ  1 
ATOM   9451  N NH1 . ARG B 1 679 ? 84.497  148.838 140.336 1.00 100.65 ? 679 ARG B NH1 1 
ATOM   9452  N NH2 . ARG B 1 679 ? 83.765  148.713 138.237 1.00 100.91 ? 679 ARG B NH2 1 
ATOM   9453  N N   . ARG B 1 680 ? 88.787  155.680 135.339 1.00 100.63 ? 680 ARG B N   1 
ATOM   9454  C CA  . ARG B 1 680 ? 89.185  156.800 134.469 1.00 96.87  ? 680 ARG B CA  1 
ATOM   9455  C C   . ARG B 1 680 ? 88.615  156.674 133.053 1.00 101.71 ? 680 ARG B C   1 
ATOM   9456  O O   . ARG B 1 680 ? 88.656  155.604 132.458 1.00 100.59 ? 680 ARG B O   1 
ATOM   9457  C CB  . ARG B 1 680 ? 90.724  156.840 134.488 1.00 98.04  ? 680 ARG B CB  1 
ATOM   9458  C CG  . ARG B 1 680 ? 91.420  157.783 133.507 1.00 98.38  ? 680 ARG B CG  1 
ATOM   9459  C CD  . ARG B 1 680 ? 92.937  157.731 133.752 1.00 102.05 ? 680 ARG B CD  1 
ATOM   9460  N NE  . ARG B 1 680 ? 93.707  158.181 132.574 1.00 102.50 ? 680 ARG B NE  1 
ATOM   9461  C CZ  . ARG B 1 680 ? 94.547  159.194 132.491 1.00 105.34 ? 680 ARG B CZ  1 
ATOM   9462  N NH1 . ARG B 1 680 ? 95.195  159.422 131.387 1.00 101.87 ? 680 ARG B NH1 1 
ATOM   9463  N NH2 . ARG B 1 680 ? 94.758  160.009 133.481 1.00 103.84 ? 680 ARG B NH2 1 
ATOM   9464  N N   . LYS B 1 681 ? 88.133  157.778 132.490 1.00 111.64 ? 681 LYS B N   1 
ATOM   9465  C CA  . LYS B 1 681 ? 87.747  157.864 131.080 1.00 109.83 ? 681 LYS B CA  1 
ATOM   9466  C C   . LYS B 1 681 ? 88.990  157.921 130.188 1.00 110.00 ? 681 LYS B C   1 
ATOM   9467  O O   . LYS B 1 681 ? 89.809  158.831 130.328 1.00 108.52 ? 681 LYS B O   1 
ATOM   9468  C CB  . LYS B 1 681 ? 86.888  159.108 130.877 1.00 104.08 ? 681 LYS B CB  1 
ATOM   9469  N N   . LYS B 1 682 ? 89.162  156.949 129.284 1.00 95.89  ? 682 LYS B N   1 
ATOM   9470  C CA  . LYS B 1 682 ? 90.370  156.825 128.452 1.00 97.99  ? 682 LYS B CA  1 
ATOM   9471  C C   . LYS B 1 682 ? 90.440  157.885 127.349 1.00 102.44 ? 682 LYS B C   1 
ATOM   9472  O O   . LYS B 1 682 ? 89.537  158.008 126.525 1.00 98.18  ? 682 LYS B O   1 
ATOM   9473  C CB  . LYS B 1 682 ? 90.475  155.413 127.855 1.00 97.43  ? 682 LYS B CB  1 
ATOM   9474  C CG  . LYS B 1 682 ? 90.812  154.359 128.918 1.00 99.21  ? 682 LYS B CG  1 
ATOM   9475  C CD  . LYS B 1 682 ? 90.956  152.988 128.258 1.00 99.55  ? 682 LYS B CD  1 
ATOM   9476  C CE  . LYS B 1 682 ? 91.336  151.914 129.274 1.00 97.65  ? 682 LYS B CE  1 
ATOM   9477  N NZ  . LYS B 1 682 ? 91.351  150.571 128.641 1.00 98.54  ? 682 LYS B NZ  1 
ATOM   9478  N N   . HIS B 1 683 ? 91.556  158.609 127.310 1.00 103.16 ? 683 HIS B N   1 
ATOM   9479  C CA  . HIS B 1 683 ? 91.975  159.478 126.204 1.00 99.60  ? 683 HIS B CA  1 
ATOM   9480  C C   . HIS B 1 683 ? 92.414  158.639 124.992 1.00 98.73  ? 683 HIS B C   1 
ATOM   9481  O O   . HIS B 1 683 ? 92.956  157.547 125.161 1.00 99.98  ? 683 HIS B O   1 
ATOM   9482  C CB  . HIS B 1 683 ? 93.090  160.398 126.735 1.00 99.52  ? 683 HIS B CB  1 
ATOM   9483  C CG  . HIS B 1 683 ? 93.811  161.206 125.690 1.00 106.44 ? 683 HIS B CG  1 
ATOM   9484  N ND1 . HIS B 1 683 ? 95.058  160.890 125.155 1.00 102.00 ? 683 HIS B ND1 1 
ATOM   9485  C CD2 . HIS B 1 683 ? 93.361  162.351 125.111 1.00 104.29 ? 683 HIS B CD2 1 
ATOM   9486  C CE1 . HIS B 1 683 ? 95.337  161.852 124.265 1.00 100.82 ? 683 HIS B CE1 1 
ATOM   9487  N NE2 . HIS B 1 683 ? 94.334  162.744 124.220 1.00 101.58 ? 683 HIS B NE2 1 
ATOM   9488  N N   . ARG B 1 684 ? 92.159  159.126 123.771 1.00 88.21  ? 684 ARG B N   1 
ATOM   9489  C CA  . ARG B 1 684 ? 92.449  158.434 122.505 1.00 86.65  ? 684 ARG B CA  1 
ATOM   9490  C C   . ARG B 1 684 ? 93.694  159.014 121.842 1.00 88.38  ? 684 ARG B C   1 
ATOM   9491  O O   . ARG B 1 684 ? 93.793  160.227 121.670 1.00 88.88  ? 684 ARG B O   1 
ATOM   9492  C CB  . ARG B 1 684 ? 91.218  158.528 121.596 1.00 86.07  ? 684 ARG B CB  1 
ATOM   9493  C CG  . ARG B 1 684 ? 91.302  157.566 120.412 1.00 81.98  ? 684 ARG B CG  1 
ATOM   9494  C CD  . ARG B 1 684 ? 89.992  157.579 119.628 1.00 81.18  ? 684 ARG B CD  1 
ATOM   9495  N NE  . ARG B 1 684 ? 89.960  156.500 118.631 1.00 88.79  ? 684 ARG B NE  1 
ATOM   9496  C CZ  . ARG B 1 684 ? 88.946  156.169 117.859 1.00 91.31  ? 684 ARG B CZ  1 
ATOM   9497  N NH1 . ARG B 1 684 ? 89.033  155.151 117.058 1.00 87.79  ? 684 ARG B NH1 1 
ATOM   9498  N NH2 . ARG B 1 684 ? 87.829  156.835 117.864 1.00 90.97  ? 684 ARG B NH2 1 
ATOM   9499  N N   . GLU B 1 685 ? 94.658  158.172 121.505 1.00 88.14  ? 685 GLU B N   1 
ATOM   9500  C CA  . GLU B 1 685 ? 95.966  158.594 120.994 1.00 88.68  ? 685 GLU B CA  1 
ATOM   9501  C C   . GLU B 1 685 ? 95.939  158.893 119.485 1.00 89.96  ? 685 GLU B C   1 
ATOM   9502  O O   . GLU B 1 685 ? 95.124  158.355 118.738 1.00 93.14  ? 685 GLU B O   1 
ATOM   9503  C CB  . GLU B 1 685 ? 97.031  157.531 121.288 1.00 88.72  ? 685 GLU B CB  1 
ATOM   9504  C CG  . GLU B 1 685 ? 97.061  156.998 122.728 1.00 89.74  ? 685 GLU B CG  1 
ATOM   9505  C CD  . GLU B 1 685 ? 97.539  157.973 123.805 1.00 91.04  ? 685 GLU B CD  1 
ATOM   9506  O OE1 . GLU B 1 685 ? 98.086  159.045 123.481 1.00 94.70  ? 685 GLU B OE1 1 
ATOM   9507  O OE2 . GLU B 1 685 ? 97.397  157.607 124.990 1.00 93.44  ? 685 GLU B OE2 1 
ATOM   9508  N N   . GLY B 1 686 ? 96.862  159.724 119.008 1.00 80.42  ? 686 GLY B N   1 
ATOM   9509  C CA  . GLY B 1 686 ? 96.906  160.137 117.607 1.00 80.34  ? 686 GLY B CA  1 
ATOM   9510  C C   . GLY B 1 686 ? 95.821  161.146 117.226 1.00 82.16  ? 686 GLY B C   1 
ATOM   9511  O O   . GLY B 1 686 ? 95.163  161.734 118.082 1.00 81.79  ? 686 GLY B O   1 
ATOM   9512  N N   . ARG B 1 687 ? 95.656  161.377 115.924 1.00 93.46  ? 687 ARG B N   1 
ATOM   9513  C CA  . ARG B 1 687 ? 94.707  162.321 115.318 1.00 91.04  ? 687 ARG B CA  1 
ATOM   9514  C C   . ARG B 1 687 ? 93.912  161.633 114.222 1.00 89.37  ? 687 ARG B C   1 
ATOM   9515  O O   . ARG B 1 687 ? 94.462  160.813 113.497 1.00 91.72  ? 687 ARG B O   1 
ATOM   9516  C CB  . ARG B 1 687 ? 95.451  163.519 114.710 1.00 93.14  ? 687 ARG B CB  1 
ATOM   9517  C CG  . ARG B 1 687 ? 96.220  164.365 115.723 1.00 96.82  ? 687 ARG B CG  1 
ATOM   9518  C CD  . ARG B 1 687 ? 96.820  165.592 115.036 1.00 95.84  ? 687 ARG B CD  1 
ATOM   9519  N NE  . ARG B 1 687 ? 97.636  166.394 115.961 1.00 101.36 ? 687 ARG B NE  1 
ATOM   9520  C CZ  . ARG B 1 687 ? 98.054  167.632 115.776 1.00 100.53 ? 687 ARG B CZ  1 
ATOM   9521  N NH1 . ARG B 1 687 ? 98.768  168.231 116.680 1.00 93.59  ? 687 ARG B NH1 1 
ATOM   9522  N NH2 . ARG B 1 687 ? 97.782  168.297 114.696 1.00 97.20  ? 687 ARG B NH2 1 
ATOM   9523  N N   . LEU B 1 688 ? 92.652  162.003 114.041 1.00 84.03  ? 688 LEU B N   1 
ATOM   9524  C CA  . LEU B 1 688 ? 91.869  161.577 112.882 1.00 88.31  ? 688 LEU B CA  1 
ATOM   9525  C C   . LEU B 1 688 ? 92.352  162.311 111.623 1.00 90.97  ? 688 LEU B C   1 
ATOM   9526  O O   . LEU B 1 688 ? 92.099  163.503 111.473 1.00 95.43  ? 688 LEU B O   1 
ATOM   9527  C CB  . LEU B 1 688 ? 90.380  161.812 113.175 1.00 92.33  ? 688 LEU B CB  1 
ATOM   9528  C CG  . LEU B 1 688 ? 89.425  161.403 112.045 1.00 93.29  ? 688 LEU B CG  1 
ATOM   9529  C CD1 . LEU B 1 688 ? 89.562  159.937 111.670 1.00 93.90  ? 688 LEU B CD1 1 
ATOM   9530  C CD2 . LEU B 1 688 ? 87.988  161.638 112.484 1.00 93.30  ? 688 LEU B CD2 1 
ATOM   9531  N N   . LEU B 1 689 ? 93.042  161.614 110.724 1.00 96.65  ? 689 LEU B N   1 
ATOM   9532  C CA  . LEU B 1 689 ? 93.647  162.181 109.518 1.00 97.36  ? 689 LEU B CA  1 
ATOM   9533  C C   . LEU B 1 689 ? 93.193  161.435 108.265 1.00 98.52  ? 689 LEU B C   1 
ATOM   9534  O O   . LEU B 1 689 ? 93.104  160.208 108.262 1.00 102.84 ? 689 LEU B O   1 
ATOM   9535  C CB  . LEU B 1 689 ? 95.182  162.145 109.635 1.00 96.65  ? 689 LEU B CB  1 
ATOM   9536  C CG  . LEU B 1 689 ? 95.776  163.002 110.763 1.00 100.75 ? 689 LEU B CG  1 
ATOM   9537  C CD1 . LEU B 1 689 ? 97.281  162.801 110.833 1.00 95.11  ? 689 LEU B CD1 1 
ATOM   9538  C CD2 . LEU B 1 689 ? 95.524  164.491 110.558 1.00 99.22  ? 689 LEU B CD2 1 
ATOM   9539  N N   . LYS B 1 690 ? 92.946  162.173 107.178 1.00 107.96 ? 690 LYS B N   1 
ATOM   9540  C CA  . LYS B 1 690 ? 92.754  161.609 105.834 1.00 111.69 ? 690 LYS B CA  1 
ATOM   9541  C C   . LYS B 1 690 ? 94.097  161.133 105.280 1.00 109.89 ? 690 LYS B C   1 
ATOM   9542  O O   . LYS B 1 690 ? 94.986  161.946 105.036 1.00 107.45 ? 690 LYS B O   1 
ATOM   9543  C CB  . LYS B 1 690 ? 92.096  162.657 104.920 1.00 109.95 ? 690 LYS B CB  1 
ATOM   9544  C CG  . LYS B 1 690 ? 91.836  162.113 103.509 1.00 109.58 ? 690 LYS B CG  1 
ATOM   9545  C CD  . LYS B 1 690 ? 91.117  163.149 102.643 1.00 108.92 ? 690 LYS B CD  1 
ATOM   9546  C CE  . LYS B 1 690 ? 91.077  162.690 101.188 1.00 109.69 ? 690 LYS B CE  1 
ATOM   9547  N NZ  . LYS B 1 690 ? 90.394  163.667 100.316 1.00 108.72 ? 690 LYS B NZ  1 
ATOM   9548  N N   . VAL B 1 691 ? 94.237  159.830 105.064 1.00 101.04 ? 691 VAL B N   1 
ATOM   9549  C CA  . VAL B 1 691 ? 95.441  159.219 104.463 1.00 102.30 ? 691 VAL B CA  1 
ATOM   9550  C C   . VAL B 1 691 ? 95.284  158.942 102.962 1.00 104.14 ? 691 VAL B C   1 
ATOM   9551  O O   . VAL B 1 691 ? 96.280  158.772 102.261 1.00 100.50 ? 691 VAL B O   1 
ATOM   9552  C CB  . VAL B 1 691 ? 95.873  157.960 105.237 1.00 97.93  ? 691 VAL B CB  1 
ATOM   9553  C CG1 . VAL B 1 691 ? 96.369  158.328 106.633 1.00 93.64  ? 691 VAL B CG1 1 
ATOM   9554  C CG2 . VAL B 1 691 ? 94.773  156.916 105.374 1.00 97.34  ? 691 VAL B CG2 1 
ATOM   9555  N N   . GLY B 1 692 ? 94.052  158.941 102.448 1.00 116.75 ? 692 GLY B N   1 
ATOM   9556  C CA  . GLY B 1 692 ? 93.742  158.692 101.040 1.00 115.94 ? 692 GLY B CA  1 
ATOM   9557  C C   . GLY B 1 692 ? 92.239  158.562 100.773 1.00 120.33 ? 692 GLY B C   1 
ATOM   9558  O O   . GLY B 1 692 ? 91.417  159.100 101.519 1.00 120.43 ? 692 GLY B O   1 
ATOM   9559  N N   . THR B 1 693 ? 91.872  157.834 99.713  1.00 132.06 ? 693 THR B N   1 
ATOM   9560  C CA  . THR B 1 693 ? 90.476  157.525 99.335  1.00 132.63 ? 693 THR B CA  1 
ATOM   9561  C C   . THR B 1 693 ? 90.167  156.037 99.553  1.00 130.69 ? 693 THR B C   1 
ATOM   9562  O O   . THR B 1 693 ? 90.925  155.172 99.112  1.00 129.54 ? 693 THR B O   1 
ATOM   9563  C CB  . THR B 1 693 ? 90.194  157.946 97.883  1.00 130.11 ? 693 THR B CB  1 
ATOM   9564  O OG1 . THR B 1 693 ? 90.503  159.313 97.721  1.00 128.04 ? 693 THR B OG1 1 
ATOM   9565  C CG2 . THR B 1 693 ? 88.728  157.779 97.492  1.00 127.99 ? 693 THR B CG2 1 
ATOM   9566  N N   . ARG B 1 694 ? 89.068  155.720 100.254 1.00 133.79 ? 694 ARG B N   1 
ATOM   9567  C CA  . ARG B 1 694 ? 88.729  154.358 100.708 1.00 133.33 ? 694 ARG B CA  1 
ATOM   9568  C C   . ARG B 1 694 ? 88.196  153.475 99.571  1.00 132.70 ? 694 ARG B C   1 
ATOM   9569  O O   . ARG B 1 694 ? 87.140  153.759 99.005  1.00 131.37 ? 694 ARG B O   1 
ATOM   9570  C CB  . ARG B 1 694 ? 87.760  154.449 101.902 1.00 132.78 ? 694 ARG B CB  1 
ATOM   9571  C CG  . ARG B 1 694 ? 87.758  153.155 102.728 1.00 132.47 ? 694 ARG B CG  1 
ATOM   9572  C CD  . ARG B 1 694 ? 86.828  153.296 103.939 1.00 132.41 ? 694 ARG B CD  1 
ATOM   9573  N NE  . ARG B 1 694 ? 86.982  152.174 104.884 1.00 135.36 ? 694 ARG B NE  1 
ATOM   9574  C CZ  . ARG B 1 694 ? 86.252  151.940 105.960 1.00 135.14 ? 694 ARG B CZ  1 
ATOM   9575  N NH1 . ARG B 1 694 ? 86.548  150.966 106.767 1.00 132.21 ? 694 ARG B NH1 1 
ATOM   9576  N NH2 . ARG B 1 694 ? 85.214  152.664 106.263 1.00 135.32 ? 694 ARG B NH2 1 
ATOM   9577  N N   . PRO B 1 699 ? 86.095  159.451 102.665 1.00 127.01 ? 699 PRO B N   1 
ATOM   9578  C CA  . PRO B 1 699 ? 87.476  159.104 102.366 1.00 128.10 ? 699 PRO B CA  1 
ATOM   9579  C C   . PRO B 1 699 ? 88.082  158.075 103.331 1.00 129.27 ? 699 PRO B C   1 
ATOM   9580  O O   . PRO B 1 699 ? 87.414  157.542 104.216 1.00 125.77 ? 699 PRO B O   1 
ATOM   9581  C CB  . PRO B 1 699 ? 88.234  160.433 102.381 1.00 125.10 ? 699 PRO B CB  1 
ATOM   9582  C CG  . PRO B 1 699 ? 87.165  161.458 102.036 1.00 125.90 ? 699 PRO B CG  1 
ATOM   9583  C CD  . PRO B 1 699 ? 85.919  160.884 102.695 1.00 125.87 ? 699 PRO B CD  1 
ATOM   9584  N N   . ASP B 1 700 ? 89.369  157.771 103.154 1.00 121.72 ? 700 ASP B N   1 
ATOM   9585  C CA  . ASP B 1 700 ? 90.128  156.922 104.072 1.00 120.33 ? 700 ASP B CA  1 
ATOM   9586  C C   . ASP B 1 700 ? 90.663  157.784 105.220 1.00 115.88 ? 700 ASP B C   1 
ATOM   9587  O O   . ASP B 1 700 ? 91.762  158.332 105.154 1.00 111.97 ? 700 ASP B O   1 
ATOM   9588  C CB  . ASP B 1 700 ? 91.230  156.181 103.297 1.00 119.14 ? 700 ASP B CB  1 
ATOM   9589  C CG  . ASP B 1 700 ? 91.853  155.017 104.067 1.00 121.12 ? 700 ASP B CG  1 
ATOM   9590  O OD1 . ASP B 1 700 ? 91.445  154.725 105.209 1.00 119.32 ? 700 ASP B OD1 1 
ATOM   9591  O OD2 . ASP B 1 700 ? 92.755  154.352 103.513 1.00 119.03 ? 700 ASP B OD2 1 
ATOM   9592  N N   . GLU B 1 701 ? 89.837  157.977 106.248 1.00 106.86 ? 701 GLU B N   1 
ATOM   9593  C CA  . GLU B 1 701 ? 90.156  158.768 107.436 1.00 108.21 ? 701 GLU B CA  1 
ATOM   9594  C C   . GLU B 1 701 ? 90.378  157.840 108.630 1.00 108.03 ? 701 GLU B C   1 
ATOM   9595  O O   . GLU B 1 701 ? 89.522  157.012 108.951 1.00 107.92 ? 701 GLU B O   1 
ATOM   9596  C CB  . GLU B 1 701 ? 89.050  159.793 107.731 1.00 109.74 ? 701 GLU B CB  1 
ATOM   9597  C CG  . GLU B 1 701 ? 88.899  160.817 106.599 1.00 112.17 ? 701 GLU B CG  1 
ATOM   9598  C CD  . GLU B 1 701 ? 87.833  161.887 106.883 1.00 112.78 ? 701 GLU B CD  1 
ATOM   9599  O OE1 . GLU B 1 701 ? 86.785  161.576 107.492 1.00 111.07 ? 701 GLU B OE1 1 
ATOM   9600  O OE2 . GLU B 1 701 ? 88.030  163.053 106.476 1.00 110.37 ? 701 GLU B OE2 1 
ATOM   9601  N N   . ARG B 1 702 ? 91.565  157.974 109.257 1.00 90.58  ? 702 ARG B N   1 
ATOM   9602  C CA  . ARG B 1 702 ? 91.977  157.035 110.339 1.00 85.40  ? 702 ARG B CA  1 
ATOM   9603  C C   . ARG B 1 702 ? 92.687  157.709 111.500 1.00 88.29  ? 702 ARG B C   1 
ATOM   9604  O O   . ARG B 1 702 ? 93.382  158.720 111.273 1.00 93.38  ? 702 ARG B O   1 
ATOM   9605  C CB  . ARG B 1 702 ? 93.035  156.083 109.778 1.00 82.94  ? 702 ARG B CB  1 
ATOM   9606  C CG  . ARG B 1 702 ? 92.610  155.353 108.510 1.00 83.69  ? 702 ARG B CG  1 
ATOM   9607  C CD  . ARG B 1 702 ? 93.608  154.238 108.249 1.00 87.72  ? 702 ARG B CD  1 
ATOM   9608  N NE  . ARG B 1 702 ? 93.432  153.691 106.910 1.00 89.74  ? 702 ARG B NE  1 
ATOM   9609  C CZ  . ARG B 1 702 ? 94.224  152.777 106.361 1.00 88.69  ? 702 ARG B CZ  1 
ATOM   9610  N NH1 . ARG B 1 702 ? 93.985  152.344 105.136 1.00 85.82  ? 702 ARG B NH1 1 
ATOM   9611  N NH2 . ARG B 1 702 ? 95.254  152.302 107.038 1.00 88.56  ? 702 ARG B NH2 1 
ATOM   9612  N N   . TRP B 1 703 ? 92.512  157.156 112.696 1.00 86.67  ? 703 TRP B N   1 
ATOM   9613  C CA  . TRP B 1 703 ? 93.271  157.602 113.858 1.00 87.08  ? 703 TRP B CA  1 
ATOM   9614  C C   . TRP B 1 703 ? 94.733  157.199 113.702 1.00 85.76  ? 703 TRP B C   1 
ATOM   9615  O O   . TRP B 1 703 ? 95.136  156.083 114.014 1.00 88.00  ? 703 TRP B O   1 
ATOM   9616  C CB  . TRP B 1 703 ? 92.604  157.096 115.130 1.00 81.52  ? 703 TRP B CB  1 
ATOM   9617  C CG  . TRP B 1 703 ? 91.370  157.880 115.432 1.00 83.41  ? 703 TRP B CG  1 
ATOM   9618  C CD1 . TRP B 1 703 ? 90.167  157.714 114.844 1.00 85.01  ? 703 TRP B CD1 1 
ATOM   9619  C CD2 . TRP B 1 703 ? 91.237  159.050 116.290 1.00 87.89  ? 703 TRP B CD2 1 
ATOM   9620  N NE1 . TRP B 1 703 ? 89.301  158.690 115.286 1.00 86.51  ? 703 TRP B NE1 1 
ATOM   9621  C CE2 . TRP B 1 703 ? 89.904  159.538 116.183 1.00 90.88  ? 703 TRP B CE2 1 
ATOM   9622  C CE3 . TRP B 1 703 ? 92.104  159.743 117.158 1.00 86.95  ? 703 TRP B CE3 1 
ATOM   9623  C CZ2 . TRP B 1 703 ? 89.455  160.657 116.895 1.00 89.93  ? 703 TRP B CZ2 1 
ATOM   9624  C CZ3 . TRP B 1 703 ? 91.657  160.854 117.893 1.00 88.19  ? 703 TRP B CZ3 1 
ATOM   9625  C CH2 . TRP B 1 703 ? 90.338  161.314 117.765 1.00 87.74  ? 703 TRP B CH2 1 
ATOM   9626  N N   . CYS B 1 704 ? 95.507  158.126 113.151 1.00 77.20  ? 704 CYS B N   1 
ATOM   9627  C CA  . CYS B 1 704 ? 96.919  157.990 112.851 1.00 71.57  ? 704 CYS B CA  1 
ATOM   9628  C C   . CYS B 1 704 ? 97.786  158.617 113.936 1.00 75.70  ? 704 CYS B C   1 
ATOM   9629  O O   . CYS B 1 704 ? 97.436  159.638 114.520 1.00 81.00  ? 704 CYS B O   1 
ATOM   9630  C CB  . CYS B 1 704 ? 97.217  158.667 111.516 1.00 83.40  ? 704 CYS B CB  1 
ATOM   9631  S SG  . CYS B 1 704 ? 96.716  157.602 110.154 1.00 95.63  ? 704 CYS B SG  1 
ATOM   9632  N N   . PHE B 1 705 ? 98.951  158.036 114.168 1.00 63.22  ? 705 PHE B N   1 
ATOM   9633  C CA  . PHE B 1 705 ? 99.934  158.498 115.129 1.00 61.68  ? 705 PHE B CA  1 
ATOM   9634  C C   . PHE B 1 705 ? 101.277 158.744 114.450 1.00 61.21  ? 705 PHE B C   1 
ATOM   9635  O O   . PHE B 1 705 ? 101.835 157.845 113.831 1.00 66.91  ? 705 PHE B O   1 
ATOM   9636  C CB  . PHE B 1 705 ? 99.977  157.441 116.221 1.00 68.31  ? 705 PHE B CB  1 
ATOM   9637  C CG  . PHE B 1 705 ? 101.058 157.596 117.253 1.00 66.77  ? 705 PHE B CG  1 
ATOM   9638  C CD1 . PHE B 1 705 ? 100.869 158.447 118.355 1.00 59.21  ? 705 PHE B CD1 1 
ATOM   9639  C CD2 . PHE B 1 705 ? 102.235 156.846 117.126 1.00 64.46  ? 705 PHE B CD2 1 
ATOM   9640  C CE1 . PHE B 1 705 ? 101.870 158.556 119.329 1.00 56.09  ? 705 PHE B CE1 1 
ATOM   9641  C CE2 . PHE B 1 705 ? 103.225 156.943 118.107 1.00 69.75  ? 705 PHE B CE2 1 
ATOM   9642  C CZ  . PHE B 1 705 ? 103.043 157.804 119.201 1.00 68.11  ? 705 PHE B CZ  1 
ATOM   9643  N N   . ARG B 1 706 ? 101.777 159.984 114.575 1.00 67.78  ? 706 ARG B N   1 
ATOM   9644  C CA  . ARG B 1 706 ? 103.009 160.414 113.854 1.00 67.96  ? 706 ARG B CA  1 
ATOM   9645  C C   . ARG B 1 706 ? 104.292 160.043 114.591 1.00 65.84  ? 706 ARG B C   1 
ATOM   9646  O O   . ARG B 1 706 ? 104.473 160.500 115.737 1.00 76.65  ? 706 ARG B O   1 
ATOM   9647  C CB  . ARG B 1 706 ? 102.947 161.933 113.662 1.00 67.24  ? 706 ARG B CB  1 
ATOM   9648  C CG  . ARG B 1 706 ? 104.132 162.467 112.851 1.00 69.10  ? 706 ARG B CG  1 
ATOM   9649  C CD  . ARG B 1 706 ? 104.018 163.977 112.631 1.00 70.91  ? 706 ARG B CD  1 
ATOM   9650  N NE  . ARG B 1 706 ? 102.980 164.299 111.640 1.00 74.10  ? 706 ARG B NE  1 
ATOM   9651  C CZ  . ARG B 1 706 ? 101.691 164.452 111.921 1.00 77.43  ? 706 ARG B CZ  1 
ATOM   9652  N NH1 . ARG B 1 706 ? 100.833 164.740 110.956 1.00 71.10  ? 706 ARG B NH1 1 
ATOM   9653  N NH2 . ARG B 1 706 ? 101.263 164.312 113.163 1.00 79.03  ? 706 ARG B NH2 1 
ATOM   9654  N N   . VAL B 1 707 ? 105.136 159.249 113.952 1.00 61.83  ? 707 VAL B N   1 
ATOM   9655  C CA  . VAL B 1 707 ? 106.465 158.857 114.436 1.00 64.70  ? 707 VAL B CA  1 
ATOM   9656  C C   . VAL B 1 707 ? 107.515 159.509 113.546 1.00 72.48  ? 707 VAL B C   1 
ATOM   9657  O O   . VAL B 1 707 ? 107.365 159.534 112.330 1.00 81.04  ? 707 VAL B O   1 
ATOM   9658  C CB  . VAL B 1 707 ? 106.623 157.331 114.441 1.00 71.93  ? 707 VAL B CB  1 
ATOM   9659  C CG1 . VAL B 1 707 ? 107.997 156.873 114.932 1.00 69.30  ? 707 VAL B CG1 1 
ATOM   9660  C CG2 . VAL B 1 707 ? 105.573 156.641 115.315 1.00 77.18  ? 707 VAL B CG2 1 
ATOM   9661  N N   . GLU B 1 708 ? 108.580 160.042 114.135 1.00 80.50  ? 708 GLU B N   1 
ATOM   9662  C CA  . GLU B 1 708 ? 109.717 160.619 113.416 1.00 72.25  ? 708 GLU B CA  1 
ATOM   9663  C C   . GLU B 1 708 ? 110.958 159.763 113.688 1.00 73.75  ? 708 GLU B C   1 
ATOM   9664  O O   . GLU B 1 708 ? 111.391 159.643 114.829 1.00 78.33  ? 708 GLU B O   1 
ATOM   9665  C CB  . GLU B 1 708 ? 109.941 162.069 113.858 1.00 71.20  ? 708 GLU B CB  1 
ATOM   9666  C CG  . GLU B 1 708 ? 108.670 162.937 113.864 1.00 76.59  ? 708 GLU B CG  1 
ATOM   9667  C CD  . GLU B 1 708 ? 108.914 164.354 114.397 1.00 87.34  ? 708 GLU B CD  1 
ATOM   9668  O OE1 . GLU B 1 708 ? 109.811 164.546 115.250 1.00 90.26  ? 708 GLU B OE1 1 
ATOM   9669  O OE2 . GLU B 1 708 ? 108.167 165.274 113.999 1.00 85.77  ? 708 GLU B OE2 1 
ATOM   9670  N N   . GLU B 1 709 ? 111.528 159.147 112.659 1.00 87.74  ? 709 GLU B N   1 
ATOM   9671  C CA  . GLU B 1 709 ? 112.724 158.310 112.761 1.00 91.73  ? 709 GLU B CA  1 
ATOM   9672  C C   . GLU B 1 709 ? 113.917 159.032 112.140 1.00 96.11  ? 709 GLU B C   1 
ATOM   9673  O O   . GLU B 1 709 ? 113.857 159.422 110.977 1.00 99.11  ? 709 GLU B O   1 
ATOM   9674  C CB  . GLU B 1 709 ? 112.479 156.957 112.067 1.00 89.53  ? 709 GLU B CB  1 
ATOM   9675  C CG  . GLU B 1 709 ? 113.727 156.056 112.075 1.00 90.00  ? 709 GLU B CG  1 
ATOM   9676  C CD  . GLU B 1 709 ? 113.595 154.749 111.274 1.00 100.24 ? 709 GLU B CD  1 
ATOM   9677  O OE1 . GLU B 1 709 ? 112.540 154.494 110.652 1.00 100.62 ? 709 GLU B OE1 1 
ATOM   9678  O OE2 . GLU B 1 709 ? 114.574 153.968 111.263 1.00 100.48 ? 709 GLU B OE2 1 
ATOM   9679  N N   . VAL B 1 710 ? 115.020 159.155 112.879 1.00 87.97  ? 710 VAL B N   1 
ATOM   9680  C CA  . VAL B 1 710 ? 116.319 159.580 112.350 1.00 83.93  ? 710 VAL B CA  1 
ATOM   9681  C C   . VAL B 1 710 ? 117.233 158.364 112.306 1.00 85.74  ? 710 VAL B C   1 
ATOM   9682  O O   . VAL B 1 710 ? 117.452 157.721 113.331 1.00 84.32  ? 710 VAL B O   1 
ATOM   9683  C CB  . VAL B 1 710 ? 116.944 160.686 113.210 1.00 83.01  ? 710 VAL B CB  1 
ATOM   9684  C CG1 . VAL B 1 710 ? 118.229 161.204 112.563 1.00 85.34  ? 710 VAL B CG1 1 
ATOM   9685  C CG2 . VAL B 1 710 ? 115.991 161.863 113.422 1.00 83.87  ? 710 VAL B CG2 1 
ATOM   9686  N N   . ASN B 1 711 ? 117.774 158.025 111.136 1.00 87.87  ? 711 ASN B N   1 
ATOM   9687  C CA  . ASN B 1 711 ? 118.552 156.800 110.958 1.00 84.19  ? 711 ASN B CA  1 
ATOM   9688  C C   . ASN B 1 711 ? 119.647 156.973 109.895 1.00 87.58  ? 711 ASN B C   1 
ATOM   9689  O O   . ASN B 1 711 ? 119.509 156.551 108.749 1.00 91.60  ? 711 ASN B O   1 
ATOM   9690  C CB  . ASN B 1 711 ? 117.568 155.660 110.656 1.00 86.19  ? 711 ASN B CB  1 
ATOM   9691  C CG  . ASN B 1 711 ? 118.174 154.279 110.796 1.00 85.84  ? 711 ASN B CG  1 
ATOM   9692  O OD1 . ASN B 1 711 ? 119.377 154.076 110.714 1.00 82.47  ? 711 ASN B OD1 1 
ATOM   9693  N ND2 . ASN B 1 711 ? 117.351 153.289 111.033 1.00 86.59  ? 711 ASN B ND2 1 
ATOM   9694  N N   . TRP B 1 712 ? 120.759 157.600 110.282 1.00 86.47  ? 712 TRP B N   1 
ATOM   9695  C CA  . TRP B 1 712 ? 121.930 157.777 109.425 1.00 86.45  ? 712 TRP B CA  1 
ATOM   9696  C C   . TRP B 1 712 ? 122.484 156.444 108.919 1.00 86.82  ? 712 TRP B C   1 
ATOM   9697  O O   . TRP B 1 712 ? 122.724 156.297 107.726 1.00 85.16  ? 712 TRP B O   1 
ATOM   9698  C CB  . TRP B 1 712 ? 123.017 158.523 110.201 1.00 85.35  ? 712 TRP B CB  1 
ATOM   9699  C CG  . TRP B 1 712 ? 122.820 159.993 110.376 1.00 87.86  ? 712 TRP B CG  1 
ATOM   9700  C CD1 . TRP B 1 712 ? 122.098 160.594 111.348 1.00 85.41  ? 712 TRP B CD1 1 
ATOM   9701  C CD2 . TRP B 1 712 ? 123.395 161.072 109.580 1.00 88.43  ? 712 TRP B CD2 1 
ATOM   9702  N NE1 . TRP B 1 712 ? 122.179 161.964 111.201 1.00 88.31  ? 712 TRP B NE1 1 
ATOM   9703  C CE2 . TRP B 1 712 ? 122.988 162.314 110.144 1.00 90.52  ? 712 TRP B CE2 1 
ATOM   9704  C CE3 . TRP B 1 712 ? 124.254 161.121 108.466 1.00 81.59  ? 712 TRP B CE3 1 
ATOM   9705  C CZ2 . TRP B 1 712 ? 123.412 163.544 109.623 1.00 84.27  ? 712 TRP B CZ2 1 
ATOM   9706  C CZ3 . TRP B 1 712 ? 124.677 162.351 107.932 1.00 83.54  ? 712 TRP B CZ3 1 
ATOM   9707  C CH2 . TRP B 1 712 ? 124.262 163.559 108.508 1.00 83.24  ? 712 TRP B CH2 1 
ATOM   9708  N N   . ALA B 1 713 ? 122.642 155.455 109.799 1.00 94.42  ? 713 ALA B N   1 
ATOM   9709  C CA  . ALA B 1 713 ? 123.241 154.170 109.448 1.00 91.36  ? 713 ALA B CA  1 
ATOM   9710  C C   . ALA B 1 713 ? 122.471 153.430 108.339 1.00 92.22  ? 713 ALA B C   1 
ATOM   9711  O O   . ALA B 1 713 ? 123.093 152.874 107.438 1.00 92.30  ? 713 ALA B O   1 
ATOM   9712  C CB  . ALA B 1 713 ? 123.343 153.331 110.725 1.00 85.85  ? 713 ALA B CB  1 
ATOM   9713  N N   . ALA B 1 714 ? 121.133 153.447 108.361 1.00 90.05  ? 714 ALA B N   1 
ATOM   9714  C CA  . ALA B 1 714 ? 120.322 152.874 107.288 1.00 87.12  ? 714 ALA B CA  1 
ATOM   9715  C C   . ALA B 1 714 ? 120.274 153.773 106.045 1.00 88.26  ? 714 ALA B C   1 
ATOM   9716  O O   . ALA B 1 714 ? 120.339 153.278 104.926 1.00 90.67  ? 714 ALA B O   1 
ATOM   9717  C CB  . ALA B 1 714 ? 118.912 152.610 107.817 1.00 84.78  ? 714 ALA B CB  1 
ATOM   9718  N N   . TRP B 1 715 ? 120.178 155.090 106.217 1.00 84.17  ? 715 TRP B N   1 
ATOM   9719  C CA  . TRP B 1 715 ? 120.070 156.041 105.107 1.00 84.69  ? 715 TRP B CA  1 
ATOM   9720  C C   . TRP B 1 715 ? 121.327 156.105 104.247 1.00 88.46  ? 715 TRP B C   1 
ATOM   9721  O O   . TRP B 1 715 ? 121.226 156.079 103.022 1.00 89.67  ? 715 TRP B O   1 
ATOM   9722  C CB  . TRP B 1 715 ? 119.728 157.420 105.662 1.00 81.95  ? 715 TRP B CB  1 
ATOM   9723  C CG  . TRP B 1 715 ? 119.830 158.548 104.691 1.00 83.22  ? 715 TRP B CG  1 
ATOM   9724  C CD1 . TRP B 1 715 ? 119.007 158.768 103.643 1.00 81.89  ? 715 TRP B CD1 1 
ATOM   9725  C CD2 . TRP B 1 715 ? 120.815 159.616 104.656 1.00 88.24  ? 715 TRP B CD2 1 
ATOM   9726  N NE1 . TRP B 1 715 ? 119.394 159.917 102.989 1.00 80.87  ? 715 TRP B NE1 1 
ATOM   9727  C CE2 . TRP B 1 715 ? 120.477 160.508 103.601 1.00 86.35  ? 715 TRP B CE2 1 
ATOM   9728  C CE3 . TRP B 1 715 ? 121.945 159.937 105.434 1.00 81.81  ? 715 TRP B CE3 1 
ATOM   9729  C CZ2 . TRP B 1 715 ? 121.193 161.681 103.353 1.00 76.99  ? 715 TRP B CZ2 1 
ATOM   9730  C CZ3 . TRP B 1 715 ? 122.685 161.101 105.178 1.00 78.21  ? 715 TRP B CZ3 1 
ATOM   9731  C CH2 . TRP B 1 715 ? 122.304 161.981 104.158 1.00 76.26  ? 715 TRP B CH2 1 
ATOM   9732  N N   . GLU B 1 716 ? 122.517 156.120 104.843 1.00 100.43 ? 716 GLU B N   1 
ATOM   9733  C CA  . GLU B 1 716 ? 123.773 156.229 104.100 1.00 96.93  ? 716 GLU B CA  1 
ATOM   9734  C C   . GLU B 1 716 ? 124.005 155.071 103.122 1.00 99.64  ? 716 GLU B C   1 
ATOM   9735  O O   . GLU B 1 716 ? 124.611 155.253 102.070 1.00 99.53  ? 716 GLU B O   1 
ATOM   9736  C CB  . GLU B 1 716 ? 124.948 156.322 105.068 1.00 99.73  ? 716 GLU B CB  1 
ATOM   9737  C CG  . GLU B 1 716 ? 125.016 157.711 105.699 1.00 104.20 ? 716 GLU B CG  1 
ATOM   9738  C CD  . GLU B 1 716 ? 126.325 157.857 106.468 1.00 106.26 ? 716 GLU B CD  1 
ATOM   9739  O OE1 . GLU B 1 716 ? 126.413 157.401 107.624 1.00 103.79 ? 716 GLU B OE1 1 
ATOM   9740  O OE2 . GLU B 1 716 ? 127.285 158.407 105.889 1.00 102.75 ? 716 GLU B OE2 1 
ATOM   9741  N N   . LYS B 1 717 ? 123.462 153.890 103.430 1.00 102.47 ? 717 LYS B N   1 
ATOM   9742  C CA  . LYS B 1 717 ? 123.500 152.699 102.570 1.00 102.53 ? 717 LYS B CA  1 
ATOM   9743  C C   . LYS B 1 717 ? 122.627 152.825 101.312 1.00 100.79 ? 717 LYS B C   1 
ATOM   9744  O O   . LYS B 1 717 ? 122.784 152.038 100.384 1.00 101.92 ? 717 LYS B O   1 
ATOM   9745  C CB  . LYS B 1 717 ? 123.121 151.472 103.415 1.00 98.34  ? 717 LYS B CB  1 
ATOM   9746  C CG  . LYS B 1 717 ? 124.141 151.239 104.541 1.00 100.11 ? 717 LYS B CG  1 
ATOM   9747  C CD  . LYS B 1 717 ? 123.706 150.125 105.498 1.00 103.56 ? 717 LYS B CD  1 
ATOM   9748  C CE  . LYS B 1 717 ? 124.710 150.057 106.654 1.00 101.38 ? 717 LYS B CE  1 
ATOM   9749  N NZ  . LYS B 1 717 ? 124.344 149.013 107.639 1.00 98.96  ? 717 LYS B NZ  1 
ATOM   9750  N N   . THR B 1 718 ? 121.739 153.821 101.253 1.00 96.19  ? 718 THR B N   1 
ATOM   9751  C CA  . THR B 1 718 ? 120.891 154.131 100.084 1.00 98.31  ? 718 THR B CA  1 
ATOM   9752  C C   . THR B 1 718 ? 121.466 155.217 99.165  1.00 98.85  ? 718 THR B C   1 
ATOM   9753  O O   . THR B 1 718 ? 120.922 155.455 98.087  1.00 97.12  ? 718 THR B O   1 
ATOM   9754  C CB  . THR B 1 718 ? 119.466 154.530 100.504 1.00 103.64 ? 718 THR B CB  1 
ATOM   9755  O OG1 . THR B 1 718 ? 119.408 155.829 101.051 1.00 101.46 ? 718 THR B OG1 1 
ATOM   9756  C CG2 . THR B 1 718 ? 118.856 153.571 101.519 1.00 99.41  ? 718 THR B CG2 1 
ATOM   9757  N N   . LEU B 1 719 ? 122.549 155.896 99.557  1.00 100.28 ? 719 LEU B N   1 
ATOM   9758  C CA  . LEU B 1 719 ? 123.123 157.003 98.789  1.00 103.20 ? 719 LEU B CA  1 
ATOM   9759  C C   . LEU B 1 719 ? 123.705 156.534 97.444  1.00 100.32 ? 719 LEU B C   1 
ATOM   9760  O O   . LEU B 1 719 ? 124.751 155.882 97.382  1.00 99.11  ? 719 LEU B O   1 
ATOM   9761  C CB  . LEU B 1 719 ? 124.142 157.776 99.651  1.00 100.14 ? 719 LEU B CB  1 
ATOM   9762  C CG  . LEU B 1 719 ? 123.569 158.368 100.953 1.00 96.94  ? 719 LEU B CG  1 
ATOM   9763  C CD1 . LEU B 1 719 ? 124.656 159.111 101.721 1.00 97.03  ? 719 LEU B CD1 1 
ATOM   9764  C CD2 . LEU B 1 719 ? 122.436 159.348 100.707 1.00 92.34  ? 719 LEU B CD2 1 
ATOM   9765  N N   . ARG C 1 74  ? 91.202  181.748 89.221  1.00 168.48 ? 74  ARG C N   1 
ATOM   9766  C CA  . ARG C 1 74  ? 91.395  182.481 90.501  1.00 168.86 ? 74  ARG C CA  1 
ATOM   9767  C C   . ARG C 1 74  ? 92.896  182.579 90.796  1.00 170.27 ? 74  ARG C C   1 
ATOM   9768  O O   . ARG C 1 74  ? 93.318  183.696 91.152  1.00 170.55 ? 74  ARG C O   1 
ATOM   9769  C CB  . ARG C 1 74  ? 90.617  181.782 91.636  1.00 168.45 ? 74  ARG C CB  1 
ATOM   9770  N N   . PHE C 1 75  ? 93.695  181.508 90.682  1.00 167.79 ? 75  PHE C N   1 
ATOM   9771  C CA  . PHE C 1 75  ? 95.122  181.493 91.095  1.00 166.40 ? 75  PHE C CA  1 
ATOM   9772  C C   . PHE C 1 75  ? 95.372  181.893 92.565  1.00 165.82 ? 75  PHE C C   1 
ATOM   9773  O O   . PHE C 1 75  ? 96.295  182.636 92.904  1.00 165.60 ? 75  PHE C O   1 
ATOM   9774  C CB  . PHE C 1 75  ? 96.023  182.224 90.086  1.00 166.49 ? 75  PHE C CB  1 
ATOM   9775  C CG  . PHE C 1 75  ? 96.231  181.453 88.803  1.00 167.45 ? 75  PHE C CG  1 
ATOM   9776  C CD1 . PHE C 1 75  ? 97.023  180.289 88.809  1.00 166.84 ? 75  PHE C CD1 1 
ATOM   9777  C CD2 . PHE C 1 75  ? 95.633  181.886 87.606  1.00 166.78 ? 75  PHE C CD2 1 
ATOM   9778  C CE1 . PHE C 1 75  ? 97.220  179.561 87.625  1.00 166.99 ? 75  PHE C CE1 1 
ATOM   9779  C CE2 . PHE C 1 75  ? 95.822  181.152 86.426  1.00 166.30 ? 75  PHE C CE2 1 
ATOM   9780  C CZ  . PHE C 1 75  ? 96.620  179.997 86.432  1.00 166.85 ? 75  PHE C CZ  1 
ATOM   9781  N N   . ASP C 1 76  ? 94.584  181.349 93.373  1.00 161.82 ? 76  ASP C N   1 
ATOM   9782  C CA  . ASP C 1 76  ? 94.919  181.253 94.794  1.00 161.88 ? 76  ASP C CA  1 
ATOM   9783  C C   . ASP C 1 76  ? 96.052  180.231 95.041  1.00 162.31 ? 76  ASP C C   1 
ATOM   9784  O O   . ASP C 1 76  ? 96.493  179.506 94.139  1.00 162.20 ? 76  ASP C O   1 
ATOM   9785  C CB  . ASP C 1 76  ? 93.643  180.939 95.602  1.00 160.98 ? 76  ASP C CB  1 
ATOM   9786  C CG  . ASP C 1 76  ? 92.902  179.645 95.220  1.00 161.24 ? 76  ASP C CG  1 
ATOM   9787  O OD1 . ASP C 1 76  ? 93.506  178.739 94.613  1.00 161.92 ? 76  ASP C OD1 1 
ATOM   9788  O OD2 . ASP C 1 76  ? 91.697  179.556 95.545  1.00 159.88 ? 76  ASP C OD2 1 
ATOM   9789  N N   . ARG C 1 77  ? 96.477  180.141 96.307  1.00 152.29 ? 77  ARG C N   1 
ATOM   9790  C CA  . ARG C 1 77  ? 97.586  179.226 96.697  1.00 153.02 ? 77  ARG C CA  1 
ATOM   9791  C C   . ARG C 1 77  ? 97.238  177.763 96.430  1.00 152.39 ? 77  ARG C C   1 
ATOM   9792  O O   . ARG C 1 77  ? 98.128  177.027 95.960  1.00 152.53 ? 77  ARG C O   1 
ATOM   9793  C CB  . ARG C 1 77  ? 97.834  179.381 98.202  1.00 150.72 ? 77  ARG C CB  1 
ATOM   9794  C CG  . ARG C 1 77  ? 98.996  178.512 98.706  1.00 152.66 ? 77  ARG C CG  1 
ATOM   9795  C CD  . ARG C 1 77  ? 98.997  178.396 100.227 1.00 152.24 ? 77  ARG C CD  1 
ATOM   9796  N NE  . ARG C 1 77  ? 97.842  177.620 100.704 1.00 152.20 ? 77  ARG C NE  1 
ATOM   9797  C CZ  . ARG C 1 77  ? 97.634  177.285 101.972 1.00 151.69 ? 77  ARG C CZ  1 
ATOM   9798  N NH1 . ARG C 1 77  ? 96.563  176.584 102.303 1.00 150.82 ? 77  ARG C NH1 1 
ATOM   9799  N NH2 . ARG C 1 77  ? 98.498  177.648 102.903 1.00 150.21 ? 77  ARG C NH2 1 
ATOM   9800  N N   . ASP C 1 78  ? 96.000  177.357 96.710  1.00 152.83 ? 78  ASP C N   1 
ATOM   9801  C CA  . ASP C 1 78  ? 95.616  175.948 96.617  1.00 152.68 ? 78  ASP C CA  1 
ATOM   9802  C C   . ASP C 1 78  ? 95.511  175.471 95.155  1.00 152.32 ? 78  ASP C C   1 
ATOM   9803  O O   . ASP C 1 78  ? 95.906  174.337 94.852  1.00 153.06 ? 78  ASP C O   1 
ATOM   9804  C CB  . ASP C 1 78  ? 94.329  175.704 97.414  1.00 154.38 ? 78  ASP C CB  1 
ATOM   9805  C CG  . ASP C 1 78  ? 94.422  176.056 98.913  1.00 155.02 ? 78  ASP C CG  1 
ATOM   9806  O OD1 . ASP C 1 78  ? 95.531  176.245 99.467  1.00 156.02 ? 78  ASP C OD1 1 
ATOM   9807  O OD2 . ASP C 1 78  ? 93.352  176.120 99.560  1.00 153.83 ? 78  ASP C OD2 1 
ATOM   9808  N N   . ARG C 1 79  ? 95.120  176.339 94.205  1.00 156.28 ? 79  ARG C N   1 
ATOM   9809  C CA  . ARG C 1 79  ? 95.336  176.058 92.774  1.00 158.03 ? 79  ARG C CA  1 
ATOM   9810  C C   . ARG C 1 79  ? 96.826  175.957 92.463  1.00 158.93 ? 79  ARG C C   1 
ATOM   9811  O O   . ARG C 1 79  ? 97.254  174.953 91.909  1.00 157.44 ? 79  ARG C O   1 
ATOM   9812  C CB  . ARG C 1 79  ? 94.645  177.089 91.855  1.00 157.76 ? 79  ARG C CB  1 
ATOM   9813  C CG  . ARG C 1 79  ? 94.893  176.733 90.373  1.00 158.69 ? 79  ARG C CG  1 
ATOM   9814  C CD  . ARG C 1 79  ? 94.241  177.698 89.380  1.00 157.88 ? 79  ARG C CD  1 
ATOM   9815  N NE  . ARG C 1 79  ? 94.726  177.462 88.003  1.00 158.99 ? 79  ARG C NE  1 
ATOM   9816  C CZ  . ARG C 1 79  ? 94.293  176.562 87.138  1.00 157.86 ? 79  ARG C CZ  1 
ATOM   9817  N NH1 . ARG C 1 79  ? 94.879  176.413 85.987  1.00 157.52 ? 79  ARG C NH1 1 
ATOM   9818  N NH2 . ARG C 1 79  ? 93.281  175.788 87.392  1.00 156.82 ? 79  ARG C NH2 1 
ATOM   9819  N N   . LEU C 1 80  ? 97.634  176.962 92.803  1.00 154.57 ? 80  LEU C N   1 
ATOM   9820  C CA  . LEU C 1 80  ? 99.043  176.963 92.399  1.00 152.06 ? 80  LEU C CA  1 
ATOM   9821  C C   . LEU C 1 80  ? 99.819  175.758 92.956  1.00 151.87 ? 80  LEU C C   1 
ATOM   9822  O O   . LEU C 1 80  ? 100.527 175.084 92.215  1.00 152.02 ? 80  LEU C O   1 
ATOM   9823  C CB  . LEU C 1 80  ? 99.695  178.300 92.787  1.00 151.79 ? 80  LEU C CB  1 
ATOM   9824  C CG  . LEU C 1 80  ? 101.173 178.398 92.373  1.00 152.15 ? 80  LEU C CG  1 
ATOM   9825  C CD1 . LEU C 1 80  ? 101.368 178.186 90.879  1.00 152.64 ? 80  LEU C CD1 1 
ATOM   9826  C CD2 . LEU C 1 80  ? 101.700 179.782 92.718  1.00 151.57 ? 80  LEU C CD2 1 
ATOM   9827  N N   . PHE C 1 81  ? 99.644  175.436 94.237  1.00 144.75 ? 81  PHE C N   1 
ATOM   9828  C CA  . PHE C 1 81  ? 100.310 174.308 94.889  1.00 143.59 ? 81  PHE C CA  1 
ATOM   9829  C C   . PHE C 1 81  ? 99.877  172.962 94.301  1.00 144.20 ? 81  PHE C C   1 
ATOM   9830  O O   . PHE C 1 81  ? 100.688 172.043 94.219  1.00 145.01 ? 81  PHE C O   1 
ATOM   9831  C CB  . PHE C 1 81  ? 100.021 174.325 96.396  1.00 143.82 ? 81  PHE C CB  1 
ATOM   9832  C CG  . PHE C 1 81  ? 100.840 175.280 97.249  1.00 145.67 ? 81  PHE C CG  1 
ATOM   9833  C CD1 . PHE C 1 81  ? 101.388 176.475 96.742  1.00 145.86 ? 81  PHE C CD1 1 
ATOM   9834  C CD2 . PHE C 1 81  ? 101.049 174.954 98.598  1.00 144.08 ? 81  PHE C CD2 1 
ATOM   9835  C CE1 . PHE C 1 81  ? 102.132 177.324 97.577  1.00 145.65 ? 81  PHE C CE1 1 
ATOM   9836  C CE2 . PHE C 1 81  ? 101.800 175.799 99.427  1.00 143.96 ? 81  PHE C CE2 1 
ATOM   9837  C CZ  . PHE C 1 81  ? 102.345 176.983 98.917  1.00 145.38 ? 81  PHE C CZ  1 
ATOM   9838  N N   . SER C 1 82  ? 98.625  172.814 93.861  1.00 150.25 ? 82  SER C N   1 
ATOM   9839  C CA  . SER C 1 82  ? 98.195  171.596 93.158  1.00 149.77 ? 82  SER C CA  1 
ATOM   9840  C C   . SER C 1 82  ? 98.672  171.568 91.691  1.00 149.46 ? 82  SER C C   1 
ATOM   9841  O O   . SER C 1 82  ? 99.054  170.506 91.204  1.00 148.02 ? 82  SER C O   1 
ATOM   9842  C CB  . SER C 1 82  ? 96.686  171.384 93.313  1.00 148.64 ? 82  SER C CB  1 
ATOM   9843  O OG  . SER C 1 82  ? 95.921  172.458 92.819  1.00 149.29 ? 82  SER C OG  1 
ATOM   9844  N N   . VAL C 1 83  ? 98.783  172.716 91.010  1.00 148.73 ? 83  VAL C N   1 
ATOM   9845  C CA  . VAL C 1 83  ? 99.359  172.832 89.651  1.00 148.38 ? 83  VAL C CA  1 
ATOM   9846  C C   . VAL C 1 83  ? 100.834 172.428 89.605  1.00 148.44 ? 83  VAL C C   1 
ATOM   9847  O O   . VAL C 1 83  ? 101.197 171.515 88.862  1.00 146.48 ? 83  VAL C O   1 
ATOM   9848  C CB  . VAL C 1 83  ? 99.151  174.254 89.080  1.00 148.13 ? 83  VAL C CB  1 
ATOM   9849  C CG1 . VAL C 1 83  ? 100.021 174.568 87.857  1.00 148.82 ? 83  VAL C CG1 1 
ATOM   9850  C CG2 . VAL C 1 83  ? 97.693  174.444 88.647  1.00 148.71 ? 83  VAL C CG2 1 
ATOM   9851  N N   . VAL C 1 84  ? 101.697 173.041 90.425  1.00 146.41 ? 84  VAL C N   1 
ATOM   9852  C CA  . VAL C 1 84  ? 103.143 172.732 90.403  1.00 144.17 ? 84  VAL C CA  1 
ATOM   9853  C C   . VAL C 1 84  ? 103.462 171.309 90.874  1.00 143.65 ? 84  VAL C C   1 
ATOM   9854  O O   . VAL C 1 84  ? 104.504 170.768 90.506  1.00 142.74 ? 84  VAL C O   1 
ATOM   9855  C CB  . VAL C 1 84  ? 103.981 173.755 91.185  1.00 143.89 ? 84  VAL C CB  1 
ATOM   9856  C CG1 . VAL C 1 84  ? 103.786 175.167 90.638  1.00 143.83 ? 84  VAL C CG1 1 
ATOM   9857  C CG2 . VAL C 1 84  ? 103.719 173.741 92.691  1.00 142.29 ? 84  VAL C CG2 1 
ATOM   9858  N N   . SER C 1 85  ? 102.561 170.668 91.632  1.00 144.34 ? 85  SER C N   1 
ATOM   9859  C CA  . SER C 1 85  ? 102.718 169.263 92.038  1.00 144.57 ? 85  SER C CA  1 
ATOM   9860  C C   . SER C 1 85  ? 102.514 168.263 90.889  1.00 142.52 ? 85  SER C C   1 
ATOM   9861  O O   . SER C 1 85  ? 103.093 167.182 90.928  1.00 139.37 ? 85  SER C O   1 
ATOM   9862  C CB  . SER C 1 85  ? 101.742 168.911 93.164  1.00 142.66 ? 85  SER C CB  1 
ATOM   9863  O OG  . SER C 1 85  ? 101.950 169.717 94.310  1.00 141.96 ? 85  SER C OG  1 
ATOM   9864  N N   . ARG C 1 86  ? 101.749 168.654 89.854  1.00 150.85 ? 86  ARG C N   1 
ATOM   9865  C CA  . ARG C 1 86  ? 101.442 167.755 88.696  1.00 151.89 ? 86  ARG C CA  1 
ATOM   9866  C C   . ARG C 1 86  ? 102.589 167.747 87.677  1.00 152.15 ? 86  ARG C C   1 
ATOM   9867  O O   . ARG C 1 86  ? 102.687 166.761 86.921  1.00 150.76 ? 86  ARG C O   1 
ATOM   9868  C CB  . ARG C 1 86  ? 100.128 168.172 88.009  1.00 150.48 ? 86  ARG C CB  1 
ATOM   9869  C CG  . ARG C 1 86  ? 98.891  167.734 88.804  1.00 150.09 ? 86  ARG C CG  1 
ATOM   9870  C CD  . ARG C 1 86  ? 97.596  167.943 88.005  1.00 149.41 ? 86  ARG C CD  1 
ATOM   9871  N NE  . ARG C 1 86  ? 97.214  169.363 87.870  1.00 150.26 ? 86  ARG C NE  1 
ATOM   9872  C CZ  . ARG C 1 86  ? 96.636  170.083 88.825  1.00 150.99 ? 86  ARG C CZ  1 
ATOM   9873  N NH1 . ARG C 1 86  ? 96.333  171.351 88.605  1.00 148.99 ? 86  ARG C NH1 1 
ATOM   9874  N NH2 . ARG C 1 86  ? 96.369  169.537 89.997  1.00 151.28 ? 86  ARG C NH2 1 
ATOM   9875  N N   . GLY C 1 87  ? 103.414 168.792 87.654  1.00 153.16 ? 87  GLY C N   1 
ATOM   9876  C CA  . GLY C 1 87  ? 104.523 168.928 86.701  1.00 150.66 ? 87  GLY C CA  1 
ATOM   9877  C C   . GLY C 1 87  ? 104.118 169.422 85.305  1.00 152.76 ? 87  GLY C C   1 
ATOM   9878  O O   . GLY C 1 87  ? 104.941 169.392 84.393  1.00 150.84 ? 87  GLY C O   1 
ATOM   9879  N N   . VAL C 1 88  ? 102.875 169.885 85.120  1.00 162.08 ? 88  VAL C N   1 
ATOM   9880  C CA  . VAL C 1 88  ? 102.381 170.455 83.853  1.00 162.16 ? 88  VAL C CA  1 
ATOM   9881  C C   . VAL C 1 88  ? 102.520 171.987 83.884  1.00 161.67 ? 88  VAL C C   1 
ATOM   9882  O O   . VAL C 1 88  ? 101.818 172.638 84.658  1.00 159.71 ? 88  VAL C O   1 
ATOM   9883  C CB  . VAL C 1 88  ? 100.914 170.045 83.599  1.00 159.88 ? 88  VAL C CB  1 
ATOM   9884  C CG1 . VAL C 1 88  ? 100.378 170.641 82.293  1.00 158.45 ? 88  VAL C CG1 1 
ATOM   9885  C CG2 . VAL C 1 88  ? 100.780 168.523 83.504  1.00 158.01 ? 88  VAL C CG2 1 
ATOM   9886  N N   . PRO C 1 89  ? 103.385 172.600 83.052  1.00 159.88 ? 89  PRO C N   1 
ATOM   9887  C CA  . PRO C 1 89  ? 103.646 174.039 83.121  1.00 158.93 ? 89  PRO C CA  1 
ATOM   9888  C C   . PRO C 1 89  ? 102.508 174.891 82.546  1.00 159.23 ? 89  PRO C C   1 
ATOM   9889  O O   . PRO C 1 89  ? 102.332 176.043 82.933  1.00 157.55 ? 89  PRO C O   1 
ATOM   9890  C CB  . PRO C 1 89  ? 104.936 174.242 82.323  1.00 158.39 ? 89  PRO C CB  1 
ATOM   9891  C CG  . PRO C 1 89  ? 104.927 173.103 81.308  1.00 158.14 ? 89  PRO C CG  1 
ATOM   9892  C CD  . PRO C 1 89  ? 104.258 171.965 82.072  1.00 157.81 ? 89  PRO C CD  1 
ATOM   9893  N N   . GLU C 1 90  ? 101.723 174.346 81.616  1.00 163.61 ? 90  GLU C N   1 
ATOM   9894  C CA  . GLU C 1 90  ? 100.731 175.120 80.853  1.00 162.84 ? 90  GLU C CA  1 
ATOM   9895  C C   . GLU C 1 90  ? 99.553  175.618 81.711  1.00 163.88 ? 90  GLU C C   1 
ATOM   9896  O O   . GLU C 1 90  ? 98.968  176.666 81.435  1.00 163.70 ? 90  GLU C O   1 
ATOM   9897  C CB  . GLU C 1 90  ? 100.210 174.267 79.685  1.00 160.58 ? 90  GLU C CB  1 
ATOM   9898  N N   . GLU C 1 91  ? 99.228  174.918 82.801  1.00 164.32 ? 91  GLU C N   1 
ATOM   9899  C CA  . GLU C 1 91  ? 98.156  175.299 83.731  1.00 163.19 ? 91  GLU C CA  1 
ATOM   9900  C C   . GLU C 1 91  ? 98.467  176.564 84.562  1.00 163.63 ? 91  GLU C C   1 
ATOM   9901  O O   . GLU C 1 91  ? 97.576  177.087 85.233  1.00 163.04 ? 91  GLU C O   1 
ATOM   9902  C CB  . GLU C 1 91  ? 97.811  174.108 84.641  1.00 163.43 ? 91  GLU C CB  1 
ATOM   9903  C CG  . GLU C 1 91  ? 97.256  172.916 83.849  1.00 163.68 ? 91  GLU C CG  1 
ATOM   9904  C CD  . GLU C 1 91  ? 96.515  171.904 84.735  1.00 164.38 ? 91  GLU C CD  1 
ATOM   9905  O OE1 . GLU C 1 91  ? 97.025  171.524 85.812  1.00 163.80 ? 91  GLU C OE1 1 
ATOM   9906  O OE2 . GLU C 1 91  ? 95.401  171.486 84.349  1.00 163.68 ? 91  GLU C OE2 1 
ATOM   9907  N N   . LEU C 1 92  ? 99.696  177.093 84.481  1.00 164.92 ? 92  LEU C N   1 
ATOM   9908  C CA  . LEU C 1 92  ? 100.083 178.400 85.028  1.00 165.36 ? 92  LEU C CA  1 
ATOM   9909  C C   . LEU C 1 92  ? 99.569  179.585 84.180  1.00 164.13 ? 92  LEU C C   1 
ATOM   9910  O O   . LEU C 1 92  ? 99.729  180.741 84.573  1.00 163.64 ? 92  LEU C O   1 
ATOM   9911  C CB  . LEU C 1 92  ? 101.622 178.463 85.163  1.00 164.77 ? 92  LEU C CB  1 
ATOM   9912  C CG  . LEU C 1 92  ? 102.253 177.412 86.094  1.00 164.40 ? 92  LEU C CG  1 
ATOM   9913  C CD1 . LEU C 1 92  ? 103.771 177.375 85.923  1.00 164.36 ? 92  LEU C CD1 1 
ATOM   9914  C CD2 . LEU C 1 92  ? 101.959 177.731 87.559  1.00 162.78 ? 92  LEU C CD2 1 
ATOM   9915  N N   . THR C 1 93  ? 98.966  179.334 83.011  1.00 167.27 ? 93  THR C N   1 
ATOM   9916  C CA  . THR C 1 93  ? 98.501  180.382 82.080  1.00 168.41 ? 93  THR C CA  1 
ATOM   9917  C C   . THR C 1 93  ? 97.502  181.336 82.751  1.00 168.85 ? 93  THR C C   1 
ATOM   9918  O O   . THR C 1 93  ? 96.414  180.927 83.153  1.00 169.47 ? 93  THR C O   1 
ATOM   9919  C CB  . THR C 1 93  ? 97.886  179.766 80.813  1.00 166.69 ? 93  THR C CB  1 
ATOM   9920  O OG1 . THR C 1 93  ? 98.855  179.008 80.130  1.00 166.49 ? 93  THR C OG1 1 
ATOM   9921  C CG2 . THR C 1 93  ? 97.399  180.820 79.820  1.00 166.21 ? 93  THR C CG2 1 
ATOM   9922  N N   . GLY C 1 94  ? 97.868  182.615 82.869  1.00 170.30 ? 94  GLY C N   1 
ATOM   9923  C CA  . GLY C 1 94  ? 97.085  183.655 83.545  1.00 170.34 ? 94  GLY C CA  1 
ATOM   9924  C C   . GLY C 1 94  ? 97.550  184.020 84.963  1.00 171.12 ? 94  GLY C C   1 
ATOM   9925  O O   . GLY C 1 94  ? 97.087  185.024 85.508  1.00 170.58 ? 94  GLY C O   1 
ATOM   9926  N N   . LEU C 1 95  ? 98.501  183.283 85.552  1.00 170.01 ? 95  LEU C N   1 
ATOM   9927  C CA  . LEU C 1 95  ? 99.054  183.612 86.872  1.00 169.67 ? 95  LEU C CA  1 
ATOM   9928  C C   . LEU C 1 95  ? 99.735  184.993 86.885  1.00 169.52 ? 95  LEU C C   1 
ATOM   9929  O O   . LEU C 1 95  ? 99.576  185.747 87.842  1.00 169.80 ? 95  LEU C O   1 
ATOM   9930  C CB  . LEU C 1 95  ? 100.011 182.480 87.294  1.00 169.12 ? 95  LEU C CB  1 
ATOM   9931  C CG  . LEU C 1 95  ? 100.733 182.674 88.644  1.00 169.26 ? 95  LEU C CG  1 
ATOM   9932  C CD1 . LEU C 1 95  ? 99.772  182.821 89.818  1.00 168.56 ? 95  LEU C CD1 1 
ATOM   9933  C CD2 . LEU C 1 95  ? 101.600 181.449 88.923  1.00 168.56 ? 95  LEU C CD2 1 
ATOM   9934  N N   . LEU C 1 96  ? 100.422 185.363 85.792  1.00 168.90 ? 96  LEU C N   1 
ATOM   9935  C CA  . LEU C 1 96  ? 101.024 186.694 85.635  1.00 168.66 ? 96  LEU C CA  1 
ATOM   9936  C C   . LEU C 1 96  ? 99.974  187.802 85.773  1.00 169.90 ? 96  LEU C C   1 
ATOM   9937  O O   . LEU C 1 96  ? 100.164 188.765 86.513  1.00 169.49 ? 96  LEU C O   1 
ATOM   9938  C CB  . LEU C 1 96  ? 101.709 186.851 84.261  1.00 169.72 ? 96  LEU C CB  1 
ATOM   9939  C CG  . LEU C 1 96  ? 102.854 185.878 83.938  1.00 169.53 ? 96  LEU C CG  1 
ATOM   9940  C CD1 . LEU C 1 96  ? 102.347 184.583 83.293  1.00 169.28 ? 96  LEU C CD1 1 
ATOM   9941  C CD2 . LEU C 1 96  ? 103.826 186.528 82.958  1.00 168.05 ? 96  LEU C CD2 1 
ATOM   9942  N N   . GLU C 1 97  ? 98.850  187.670 85.065  1.00 172.75 ? 97  GLU C N   1 
ATOM   9943  C CA  . GLU C 1 97  ? 97.779  188.670 85.068  1.00 171.98 ? 97  GLU C CA  1 
ATOM   9944  C C   . GLU C 1 97  ? 97.141  188.806 86.452  1.00 172.68 ? 97  GLU C C   1 
ATOM   9945  O O   . GLU C 1 97  ? 96.921  189.923 86.913  1.00 170.83 ? 97  GLU C O   1 
ATOM   9946  C CB  . GLU C 1 97  ? 96.702  188.312 84.036  1.00 169.59 ? 97  GLU C CB  1 
ATOM   9947  N N   . TYR C 1 98  ? 96.892  187.693 87.148  1.00 173.59 ? 98  TYR C N   1 
ATOM   9948  C CA  . TYR C 1 98  ? 96.302  187.742 88.486  1.00 172.90 ? 98  TYR C CA  1 
ATOM   9949  C C   . TYR C 1 98  ? 97.237  188.399 89.510  1.00 173.08 ? 98  TYR C C   1 
ATOM   9950  O O   . TYR C 1 98  ? 96.800  189.264 90.272  1.00 173.24 ? 98  TYR C O   1 
ATOM   9951  C CB  . TYR C 1 98  ? 95.904  186.336 88.936  1.00 172.63 ? 98  TYR C CB  1 
ATOM   9952  C CG  . TYR C 1 98  ? 95.135  186.347 90.242  1.00 173.38 ? 98  TYR C CG  1 
ATOM   9953  C CD1 . TYR C 1 98  ? 93.782  186.740 90.249  1.00 172.92 ? 98  TYR C CD1 1 
ATOM   9954  C CD2 . TYR C 1 98  ? 95.768  186.003 91.451  1.00 172.51 ? 98  TYR C CD2 1 
ATOM   9955  C CE1 . TYR C 1 98  ? 93.054  186.755 91.456  1.00 172.88 ? 98  TYR C CE1 1 
ATOM   9956  C CE2 . TYR C 1 98  ? 95.046  186.021 92.659  1.00 172.91 ? 98  TYR C CE2 1 
ATOM   9957  C CZ  . TYR C 1 98  ? 93.681  186.382 92.662  1.00 173.61 ? 98  TYR C CZ  1 
ATOM   9958  O OH  . TYR C 1 98  ? 92.969  186.381 93.819  1.00 171.77 ? 98  TYR C OH  1 
ATOM   9959  N N   . LEU C 1 99  ? 98.525  188.041 89.512  1.00 172.99 ? 99  LEU C N   1 
ATOM   9960  C CA  . LEU C 1 99  ? 99.524  188.641 90.404  1.00 173.81 ? 99  LEU C CA  1 
ATOM   9961  C C   . LEU C 1 99  ? 99.658  190.149 90.156  1.00 173.47 ? 99  LEU C C   1 
ATOM   9962  O O   . LEU C 1 99  ? 99.575  190.938 91.098  1.00 172.04 ? 99  LEU C O   1 
ATOM   9963  C CB  . LEU C 1 99  ? 100.876 187.934 90.215  1.00 173.48 ? 99  LEU C CB  1 
ATOM   9964  C CG  . LEU C 1 99  ? 100.917 186.490 90.741  1.00 173.13 ? 99  LEU C CG  1 
ATOM   9965  C CD1 . LEU C 1 99  ? 102.217 185.835 90.286  1.00 172.85 ? 99  LEU C CD1 1 
ATOM   9966  C CD2 . LEU C 1 99  ? 100.841 186.419 92.265  1.00 170.64 ? 99  LEU C CD2 1 
ATOM   9967  N N   . ARG C 1 100 ? 99.781  190.570 88.890  1.00 175.73 ? 100 ARG C N   1 
ATOM   9968  C CA  . ARG C 1 100 ? 99.866  191.992 88.514  1.00 175.75 ? 100 ARG C CA  1 
ATOM   9969  C C   . ARG C 1 100 ? 98.594  192.774 88.852  1.00 175.90 ? 100 ARG C C   1 
ATOM   9970  O O   . ARG C 1 100 ? 98.690  193.870 89.401  1.00 175.95 ? 100 ARG C O   1 
ATOM   9971  C CB  . ARG C 1 100 ? 100.194 192.115 87.019  1.00 174.90 ? 100 ARG C CB  1 
ATOM   9972  C CG  . ARG C 1 100 ? 101.658 191.762 86.723  1.00 174.09 ? 100 ARG C CG  1 
ATOM   9973  C CD  . ARG C 1 100 ? 101.925 191.850 85.219  1.00 173.86 ? 100 ARG C CD  1 
ATOM   9974  N NE  . ARG C 1 100 ? 103.358 191.727 84.905  1.00 175.81 ? 100 ARG C NE  1 
ATOM   9975  C CZ  . ARG C 1 100 ? 103.915 191.859 83.717  1.00 175.45 ? 100 ARG C CZ  1 
ATOM   9976  N NH1 . ARG C 1 100 ? 105.202 191.771 83.590  1.00 174.36 ? 100 ARG C NH1 1 
ATOM   9977  N NH2 . ARG C 1 100 ? 103.218 192.074 82.641  1.00 174.77 ? 100 ARG C NH2 1 
ATOM   9978  N N   . TRP C 1 101 ? 97.411  192.220 88.585  1.00 177.48 ? 101 TRP C N   1 
ATOM   9979  C CA  . TRP C 1 101 ? 96.132  192.896 88.842  1.00 177.61 ? 101 TRP C CA  1 
ATOM   9980  C C   . TRP C 1 101 ? 95.860  193.093 90.342  1.00 177.80 ? 101 TRP C C   1 
ATOM   9981  O O   . TRP C 1 101 ? 95.381  194.148 90.752  1.00 176.21 ? 101 TRP C O   1 
ATOM   9982  C CB  . TRP C 1 101 ? 95.007  192.118 88.143  1.00 177.18 ? 101 TRP C CB  1 
ATOM   9983  C CG  . TRP C 1 101 ? 93.665  192.783 88.119  1.00 178.34 ? 101 TRP C CG  1 
ATOM   9984  C CD1 . TRP C 1 101 ? 93.212  193.569 87.115  1.00 177.28 ? 101 TRP C CD1 1 
ATOM   9985  C CD2 . TRP C 1 101 ? 92.599  192.772 89.121  1.00 179.09 ? 101 TRP C CD2 1 
ATOM   9986  N NE1 . TRP C 1 101 ? 91.950  194.034 87.417  1.00 177.77 ? 101 TRP C NE1 1 
ATOM   9987  C CE2 . TRP C 1 101 ? 91.522  193.579 88.644  1.00 179.18 ? 101 TRP C CE2 1 
ATOM   9988  C CE3 . TRP C 1 101 ? 92.428  192.168 90.384  1.00 177.55 ? 101 TRP C CE3 1 
ATOM   9989  C CZ2 . TRP C 1 101 ? 90.346  193.780 89.380  1.00 177.81 ? 101 TRP C CZ2 1 
ATOM   9990  C CZ3 . TRP C 1 101 ? 91.252  192.361 91.132  1.00 176.74 ? 101 TRP C CZ3 1 
ATOM   9991  C CH2 . TRP C 1 101 ? 90.210  193.165 90.634  1.00 177.01 ? 101 TRP C CH2 1 
ATOM   9992  N N   . ASN C 1 102 ? 96.235  192.122 91.182  1.00 177.50 ? 102 ASN C N   1 
ATOM   9993  C CA  . ASN C 1 102 ? 96.175  192.249 92.645  1.00 177.02 ? 102 ASN C CA  1 
ATOM   9994  C C   . ASN C 1 102 ? 97.383  193.003 93.251  1.00 177.42 ? 102 ASN C C   1 
ATOM   9995  O O   . ASN C 1 102 ? 97.333  193.386 94.418  1.00 177.32 ? 102 ASN C O   1 
ATOM   9996  C CB  . ASN C 1 102 ? 96.018  190.855 93.274  1.00 177.84 ? 102 ASN C CB  1 
ATOM   9997  C CG  . ASN C 1 102 ? 94.664  190.234 92.984  1.00 177.97 ? 102 ASN C CG  1 
ATOM   9998  O OD1 . ASN C 1 102 ? 93.696  190.443 93.699  1.00 176.83 ? 102 ASN C OD1 1 
ATOM   9999  N ND2 . ASN C 1 102 ? 94.556  189.451 91.942  1.00 177.69 ? 102 ASN C ND2 1 
ATOM   10000 N N   . SER C 1 103 ? 98.458  193.228 92.488  1.00 175.44 ? 103 SER C N   1 
ATOM   10001 C CA  . SER C 1 103 ? 99.767  193.758 92.925  1.00 175.40 ? 103 SER C CA  1 
ATOM   10002 C C   . SER C 1 103 ? 100.514 192.879 93.953  1.00 175.70 ? 103 SER C C   1 
ATOM   10003 O O   . SER C 1 103 ? 101.300 193.377 94.763  1.00 174.28 ? 103 SER C O   1 
ATOM   10004 C CB  . SER C 1 103 ? 99.673  195.244 93.315  1.00 174.43 ? 103 SER C CB  1 
ATOM   10005 O OG  . SER C 1 103 ? 99.022  195.439 94.558  1.00 175.43 ? 103 SER C OG  1 
ATOM   10006 N N   . LYS C 1 104 ? 100.268 191.561 93.936  1.00 171.66 ? 104 LYS C N   1 
ATOM   10007 C CA  . LYS C 1 104 ? 100.829 190.584 94.891  1.00 170.50 ? 104 LYS C CA  1 
ATOM   10008 C C   . LYS C 1 104 ? 102.016 189.810 94.312  1.00 171.29 ? 104 LYS C C   1 
ATOM   10009 O O   . LYS C 1 104 ? 102.218 189.783 93.100  1.00 170.39 ? 104 LYS C O   1 
ATOM   10010 C CB  . LYS C 1 104 ? 99.726  189.634 95.384  1.00 170.25 ? 104 LYS C CB  1 
ATOM   10011 C CG  . LYS C 1 104 ? 98.625  190.412 96.114  1.00 170.92 ? 104 LYS C CG  1 
ATOM   10012 C CD  . LYS C 1 104 ? 97.665  189.513 96.905  1.00 170.42 ? 104 LYS C CD  1 
ATOM   10013 C CE  . LYS C 1 104 ? 98.311  188.937 98.171  1.00 171.00 ? 104 LYS C CE  1 
ATOM   10014 N NZ  . LYS C 1 104 ? 98.597  189.987 99.180  1.00 170.60 ? 104 LYS C NZ  1 
ATOM   10015 N N   . TYR C 1 105 ? 102.776 189.150 95.188  1.00 164.08 ? 105 TYR C N   1 
ATOM   10016 C CA  . TYR C 1 105 ? 103.985 188.390 94.856  1.00 162.26 ? 105 TYR C CA  1 
ATOM   10017 C C   . TYR C 1 105 ? 103.919 186.944 95.374  1.00 161.39 ? 105 TYR C C   1 
ATOM   10018 O O   . TYR C 1 105 ? 103.373 186.692 96.447  1.00 160.84 ? 105 TYR C O   1 
ATOM   10019 C CB  . TYR C 1 105 ? 105.211 189.106 95.445  1.00 161.34 ? 105 TYR C CB  1 
ATOM   10020 C CG  . TYR C 1 105 ? 105.349 190.581 95.117  1.00 162.38 ? 105 TYR C CG  1 
ATOM   10021 C CD1 . TYR C 1 105 ? 105.601 190.994 93.796  1.00 162.22 ? 105 TYR C CD1 1 
ATOM   10022 C CD2 . TYR C 1 105 ? 105.256 191.541 96.143  1.00 161.17 ? 105 TYR C CD2 1 
ATOM   10023 C CE1 . TYR C 1 105 ? 105.779 192.360 93.506  1.00 161.96 ? 105 TYR C CE1 1 
ATOM   10024 C CE2 . TYR C 1 105 ? 105.419 192.908 95.852  1.00 161.84 ? 105 TYR C CE2 1 
ATOM   10025 C CZ  . TYR C 1 105 ? 105.691 193.320 94.533  1.00 162.09 ? 105 TYR C CZ  1 
ATOM   10026 O OH  . TYR C 1 105 ? 105.885 194.630 94.245  1.00 160.33 ? 105 TYR C OH  1 
ATOM   10027 N N   . LEU C 1 106 ? 104.555 185.999 94.675  1.00 150.03 ? 106 LEU C N   1 
ATOM   10028 C CA  . LEU C 1 106 ? 104.600 184.576 95.062  1.00 149.32 ? 106 LEU C CA  1 
ATOM   10029 C C   . LEU C 1 106 ? 105.326 184.298 96.395  1.00 151.31 ? 106 LEU C C   1 
ATOM   10030 O O   . LEU C 1 106 ? 105.218 183.198 96.934  1.00 150.36 ? 106 LEU C O   1 
ATOM   10031 C CB  . LEU C 1 106 ? 105.242 183.758 93.925  1.00 149.54 ? 106 LEU C CB  1 
ATOM   10032 C CG  . LEU C 1 106 ? 104.417 183.685 92.632  1.00 150.79 ? 106 LEU C CG  1 
ATOM   10033 C CD1 . LEU C 1 106 ? 105.191 182.898 91.579  1.00 149.77 ? 106 LEU C CD1 1 
ATOM   10034 C CD2 . LEU C 1 106 ? 103.081 182.989 92.866  1.00 152.39 ? 106 LEU C CD2 1 
ATOM   10035 N N   . THR C 1 107 ? 106.057 185.274 96.938  1.00 156.75 ? 107 THR C N   1 
ATOM   10036 C CA  . THR C 1 107 ? 106.712 185.200 98.261  1.00 155.38 ? 107 THR C CA  1 
ATOM   10037 C C   . THR C 1 107 ? 105.966 185.954 99.366  1.00 155.20 ? 107 THR C C   1 
ATOM   10038 O O   . THR C 1 107 ? 106.445 186.000 100.500 1.00 155.29 ? 107 THR C O   1 
ATOM   10039 C CB  . THR C 1 107 ? 108.182 185.646 98.195  1.00 154.37 ? 107 THR C CB  1 
ATOM   10040 O OG1 . THR C 1 107 ? 108.325 186.968 97.736  1.00 154.90 ? 107 THR C OG1 1 
ATOM   10041 C CG2 . THR C 1 107 ? 108.970 184.762 97.246  1.00 154.02 ? 107 THR C CG2 1 
ATOM   10042 N N   . ASP C 1 108 ? 104.789 186.528 99.090  1.00 155.88 ? 108 ASP C N   1 
ATOM   10043 C CA  . ASP C 1 108 ? 103.905 187.065 100.131 1.00 156.33 ? 108 ASP C CA  1 
ATOM   10044 C C   . ASP C 1 108 ? 103.185 185.933 100.891 1.00 156.00 ? 108 ASP C C   1 
ATOM   10045 O O   . ASP C 1 108 ? 102.951 184.856 100.342 1.00 155.96 ? 108 ASP C O   1 
ATOM   10046 C CB  . ASP C 1 108 ? 102.896 188.045 99.512  1.00 156.90 ? 108 ASP C CB  1 
ATOM   10047 C CG  . ASP C 1 108 ? 102.140 188.864 100.566 1.00 157.28 ? 108 ASP C CG  1 
ATOM   10048 O OD1 . ASP C 1 108 ? 102.648 189.012 101.697 1.00 156.00 ? 108 ASP C OD1 1 
ATOM   10049 O OD2 . ASP C 1 108 ? 101.028 189.346 100.264 1.00 157.10 ? 108 ASP C OD2 1 
ATOM   10050 N N   . SER C 1 109 ? 102.779 186.172 102.142 1.00 151.54 ? 109 SER C N   1 
ATOM   10051 C CA  . SER C 1 109 ? 102.196 185.156 103.043 1.00 152.67 ? 109 SER C CA  1 
ATOM   10052 C C   . SER C 1 109 ? 101.026 184.376 102.422 1.00 153.60 ? 109 SER C C   1 
ATOM   10053 O O   . SER C 1 109 ? 100.929 183.159 102.591 1.00 152.91 ? 109 SER C O   1 
ATOM   10054 C CB  . SER C 1 109 ? 101.744 185.842 104.338 1.00 151.35 ? 109 SER C CB  1 
ATOM   10055 O OG  . SER C 1 109 ? 101.168 184.918 105.238 1.00 150.29 ? 109 SER C OG  1 
ATOM   10056 N N   . ALA C 1 110 ? 100.202 185.043 101.610 1.00 152.06 ? 110 ALA C N   1 
ATOM   10057 C CA  . ALA C 1 110 ? 99.069  184.448 100.902 1.00 150.46 ? 110 ALA C CA  1 
ATOM   10058 C C   . ALA C 1 110 ? 99.427  183.243 100.005 1.00 151.80 ? 110 ALA C C   1 
ATOM   10059 O O   . ALA C 1 110 ? 98.551  182.428 99.737  1.00 152.76 ? 110 ALA C O   1 
ATOM   10060 C CB  . ALA C 1 110 ? 98.408  185.557 100.077 1.00 149.74 ? 110 ALA C CB  1 
ATOM   10061 N N   . TYR C 1 111 ? 100.685 183.095 99.574  1.00 152.16 ? 111 TYR C N   1 
ATOM   10062 C CA  . TYR C 1 111 ? 101.178 181.993 98.735  1.00 151.30 ? 111 TYR C CA  1 
ATOM   10063 C C   . TYR C 1 111 ? 102.089 181.007 99.491  1.00 150.40 ? 111 TYR C C   1 
ATOM   10064 O O   . TYR C 1 111 ? 102.923 180.338 98.887  1.00 150.07 ? 111 TYR C O   1 
ATOM   10065 C CB  . TYR C 1 111 ? 101.823 182.571 97.466  1.00 152.43 ? 111 TYR C CB  1 
ATOM   10066 C CG  . TYR C 1 111 ? 100.823 183.124 96.471  1.00 151.55 ? 111 TYR C CG  1 
ATOM   10067 C CD1 . TYR C 1 111 ? 100.251 182.260 95.519  1.00 150.52 ? 111 TYR C CD1 1 
ATOM   10068 C CD2 . TYR C 1 111 ? 100.460 184.481 96.495  1.00 151.87 ? 111 TYR C CD2 1 
ATOM   10069 C CE1 . TYR C 1 111 ? 99.315  182.749 94.591  1.00 152.32 ? 111 TYR C CE1 1 
ATOM   10070 C CE2 . TYR C 1 111 ? 99.509  184.968 95.581  1.00 151.83 ? 111 TYR C CE2 1 
ATOM   10071 C CZ  . TYR C 1 111 ? 98.934  184.103 94.630  1.00 153.69 ? 111 TYR C CZ  1 
ATOM   10072 O OH  . TYR C 1 111 ? 97.999  184.573 93.764  1.00 155.97 ? 111 TYR C OH  1 
ATOM   10073 N N   . THR C 1 112 ? 101.939 180.882 100.813 1.00 144.04 ? 112 THR C N   1 
ATOM   10074 C CA  . THR C 1 112 ? 102.770 180.005 101.656 1.00 145.72 ? 112 THR C CA  1 
ATOM   10075 C C   . THR C 1 112 ? 101.959 178.937 102.396 1.00 145.60 ? 112 THR C C   1 
ATOM   10076 O O   . THR C 1 112 ? 100.790 179.144 102.730 1.00 147.17 ? 112 THR C O   1 
ATOM   10077 C CB  . THR C 1 112 ? 103.629 180.809 102.641 1.00 146.74 ? 112 THR C CB  1 
ATOM   10078 O OG1 . THR C 1 112 ? 102.844 181.481 103.595 1.00 145.16 ? 112 THR C OG1 1 
ATOM   10079 C CG2 . THR C 1 112 ? 104.506 181.842 101.942 1.00 145.06 ? 112 THR C CG2 1 
ATOM   10080 N N   . GLU C 1 113 ? 102.552 177.759 102.624 1.00 141.01 ? 113 GLU C N   1 
ATOM   10081 C CA  . GLU C 1 113 ? 101.921 176.676 103.390 1.00 141.78 ? 113 GLU C CA  1 
ATOM   10082 C C   . GLU C 1 113 ? 101.751 177.046 104.878 1.00 142.07 ? 113 GLU C C   1 
ATOM   10083 O O   . GLU C 1 113 ? 102.495 177.861 105.426 1.00 140.63 ? 113 GLU C O   1 
ATOM   10084 C CB  . GLU C 1 113 ? 102.689 175.351 103.208 1.00 141.77 ? 113 GLU C CB  1 
ATOM   10085 C CG  . GLU C 1 113 ? 101.769 174.137 103.223 1.00 140.76 ? 113 GLU C CG  1 
ATOM   10086 C CD  . GLU C 1 113 ? 102.411 172.859 102.671 1.00 142.75 ? 113 GLU C CD  1 
ATOM   10087 O OE1 . GLU C 1 113 ? 103.340 172.317 103.296 1.00 142.30 ? 113 GLU C OE1 1 
ATOM   10088 O OE2 . GLU C 1 113 ? 101.979 172.369 101.612 1.00 143.85 ? 113 GLU C OE2 1 
ATOM   10089 N N   . GLY C 1 114 ? 100.751 176.468 105.548 1.00 142.83 ? 114 GLY C N   1 
ATOM   10090 C CA  . GLY C 1 114 ? 100.380 176.829 106.919 1.00 141.81 ? 114 GLY C CA  1 
ATOM   10091 C C   . GLY C 1 114 ? 101.436 176.492 107.976 1.00 143.13 ? 114 GLY C C   1 
ATOM   10092 O O   . GLY C 1 114 ? 102.120 175.471 107.890 1.00 142.31 ? 114 GLY C O   1 
ATOM   10093 N N   . SER C 1 115 ? 101.542 177.337 109.006 1.00 140.99 ? 115 SER C N   1 
ATOM   10094 C CA  . SER C 1 115 ? 102.474 177.205 110.145 1.00 139.73 ? 115 SER C CA  1 
ATOM   10095 C C   . SER C 1 115 ? 103.965 177.173 109.766 1.00 139.27 ? 115 SER C C   1 
ATOM   10096 O O   . SER C 1 115 ? 104.797 176.681 110.525 1.00 137.08 ? 115 SER C O   1 
ATOM   10097 C CB  . SER C 1 115 ? 102.086 176.034 111.062 1.00 138.79 ? 115 SER C CB  1 
ATOM   10098 O OG  . SER C 1 115 ? 100.743 176.166 111.491 1.00 138.05 ? 115 SER C OG  1 
ATOM   10099 N N   . THR C 1 116 ? 104.320 177.706 108.596 1.00 138.40 ? 116 THR C N   1 
ATOM   10100 C CA  . THR C 1 116 ? 105.695 177.807 108.077 1.00 137.46 ? 116 THR C CA  1 
ATOM   10101 C C   . THR C 1 116 ? 105.799 178.962 107.056 1.00 134.93 ? 116 THR C C   1 
ATOM   10102 O O   . THR C 1 116 ? 104.905 179.802 106.985 1.00 136.12 ? 116 THR C O   1 
ATOM   10103 C CB  . THR C 1 116 ? 106.142 176.436 107.525 1.00 134.07 ? 116 THR C CB  1 
ATOM   10104 O OG1 . THR C 1 116 ? 107.496 176.471 107.158 1.00 131.58 ? 116 THR C OG1 1 
ATOM   10105 C CG2 . THR C 1 116 ? 105.354 175.954 106.309 1.00 132.40 ? 116 THR C CG2 1 
ATOM   10106 N N   . GLY C 1 117 ? 106.877 179.039 106.271 1.00 121.64 ? 117 GLY C N   1 
ATOM   10107 C CA  . GLY C 1 117 ? 107.057 180.007 105.174 1.00 124.46 ? 117 GLY C CA  1 
ATOM   10108 C C   . GLY C 1 117 ? 107.140 179.369 103.781 1.00 124.93 ? 117 GLY C C   1 
ATOM   10109 O O   . GLY C 1 117 ? 107.437 180.044 102.801 1.00 125.66 ? 117 GLY C O   1 
ATOM   10110 N N   . LYS C 1 118 ? 106.921 178.055 103.702 1.00 121.52 ? 118 LYS C N   1 
ATOM   10111 C CA  . LYS C 1 118 ? 107.155 177.189 102.541 1.00 121.91 ? 118 LYS C CA  1 
ATOM   10112 C C   . LYS C 1 118 ? 106.391 177.655 101.302 1.00 120.73 ? 118 LYS C C   1 
ATOM   10113 O O   . LYS C 1 118 ? 105.169 177.763 101.343 1.00 125.48 ? 118 LYS C O   1 
ATOM   10114 C CB  . LYS C 1 118 ? 106.755 175.785 102.994 1.00 122.47 ? 118 LYS C CB  1 
ATOM   10115 C CG  . LYS C 1 118 ? 106.943 174.648 101.988 1.00 121.32 ? 118 LYS C CG  1 
ATOM   10116 C CD  . LYS C 1 118 ? 106.571 173.363 102.736 1.00 123.93 ? 118 LYS C CD  1 
ATOM   10117 C CE  . LYS C 1 118 ? 106.426 172.138 101.841 1.00 123.38 ? 118 LYS C CE  1 
ATOM   10118 N NZ  . LYS C 1 118 ? 105.740 171.051 102.581 1.00 125.35 ? 118 LYS C NZ  1 
ATOM   10119 N N   . THR C 1 119 ? 107.105 177.953 100.221 1.00 126.50 ? 119 THR C N   1 
ATOM   10120 C CA  . THR C 1 119 ? 106.562 178.576 99.001  1.00 129.18 ? 119 THR C CA  1 
ATOM   10121 C C   . THR C 1 119 ? 106.169 177.562 97.930  1.00 127.83 ? 119 THR C C   1 
ATOM   10122 O O   . THR C 1 119 ? 106.524 176.383 97.992  1.00 126.85 ? 119 THR C O   1 
ATOM   10123 C CB  . THR C 1 119 ? 107.559 179.581 98.398  1.00 131.26 ? 119 THR C CB  1 
ATOM   10124 O OG1 . THR C 1 119 ? 108.700 178.909 97.916  1.00 130.67 ? 119 THR C OG1 1 
ATOM   10125 C CG2 . THR C 1 119 ? 108.019 180.654 99.378  1.00 129.15 ? 119 THR C CG2 1 
ATOM   10126 N N   . CYS C 1 120 ? 105.503 178.037 96.882  1.00 131.76 ? 120 CYS C N   1 
ATOM   10127 C CA  . CYS C 1 120 ? 105.210 177.272 95.666  1.00 133.51 ? 120 CYS C CA  1 
ATOM   10128 C C   . CYS C 1 120 ? 106.454 176.671 94.997  1.00 135.32 ? 120 CYS C C   1 
ATOM   10129 O O   . CYS C 1 120 ? 106.380 175.565 94.471  1.00 134.36 ? 120 CYS C O   1 
ATOM   10130 C CB  . CYS C 1 120 ? 104.467 178.192 94.684  1.00 134.14 ? 120 CYS C CB  1 
ATOM   10131 S SG  . CYS C 1 120 ? 105.378 179.740 94.441  1.00 135.11 ? 120 CYS C SG  1 
ATOM   10132 N N   . LEU C 1 121 ? 107.616 177.331 95.051  1.00 128.91 ? 121 LEU C N   1 
ATOM   10133 C CA  . LEU C 1 121 ? 108.861 176.771 94.520  1.00 127.17 ? 121 LEU C CA  1 
ATOM   10134 C C   . LEU C 1 121 ? 109.329 175.559 95.339  1.00 127.63 ? 121 LEU C C   1 
ATOM   10135 O O   . LEU C 1 121 ? 109.757 174.563 94.766  1.00 130.87 ? 121 LEU C O   1 
ATOM   10136 C CB  . LEU C 1 121 ? 109.927 177.874 94.439  1.00 125.63 ? 121 LEU C CB  1 
ATOM   10137 C CG  . LEU C 1 121 ? 111.269 177.415 93.840  1.00 125.39 ? 121 LEU C CG  1 
ATOM   10138 C CD1 . LEU C 1 121 ? 111.158 177.114 92.350  1.00 126.27 ? 121 LEU C CD1 1 
ATOM   10139 C CD2 . LEU C 1 121 ? 112.320 178.503 94.024  1.00 125.94 ? 121 LEU C CD2 1 
ATOM   10140 N N   . MET C 1 122 ? 109.206 175.588 96.663  1.00 114.28 ? 122 MET C N   1 
ATOM   10141 C CA  . MET C 1 122 ? 109.506 174.409 97.476  1.00 114.83 ? 122 MET C CA  1 
ATOM   10142 C C   . MET C 1 122 ? 108.539 173.258 97.150  1.00 117.83 ? 122 MET C C   1 
ATOM   10143 O O   . MET C 1 122 ? 108.975 172.129 96.940  1.00 114.54 ? 122 MET C O   1 
ATOM   10144 C CB  . MET C 1 122 ? 109.483 174.798 98.957  1.00 116.99 ? 122 MET C CB  1 
ATOM   10145 C CG  . MET C 1 122 ? 110.522 175.879 99.253  1.00 112.92 ? 122 MET C CG  1 
ATOM   10146 S SD  . MET C 1 122 ? 110.566 176.400 100.974 1.00 113.27 ? 122 MET C SD  1 
ATOM   10147 C CE  . MET C 1 122 ? 111.225 178.064 100.760 1.00 113.37 ? 122 MET C CE  1 
ATOM   10148 N N   . LYS C 1 123 ? 107.238 173.546 96.996  1.00 129.75 ? 123 LYS C N   1 
ATOM   10149 C CA  . LYS C 1 123 ? 106.210 172.589 96.550  1.00 128.03 ? 123 LYS C CA  1 
ATOM   10150 C C   . LYS C 1 123 ? 106.527 171.978 95.174  1.00 128.17 ? 123 LYS C C   1 
ATOM   10151 O O   . LYS C 1 123 ? 106.322 170.785 94.977  1.00 128.74 ? 123 LYS C O   1 
ATOM   10152 C CB  . LYS C 1 123 ? 104.843 173.300 96.560  1.00 127.22 ? 123 LYS C CB  1 
ATOM   10153 C CG  . LYS C 1 123 ? 103.633 172.364 96.609  1.00 130.13 ? 123 LYS C CG  1 
ATOM   10154 C CD  . LYS C 1 123 ? 103.442 171.708 97.976  1.00 129.01 ? 123 LYS C CD  1 
ATOM   10155 C CE  . LYS C 1 123 ? 102.148 170.902 98.008  1.00 129.46 ? 123 LYS C CE  1 
ATOM   10156 N NZ  . LYS C 1 123 ? 101.912 170.298 99.335  1.00 128.58 ? 123 LYS C NZ  1 
ATOM   10157 N N   . ALA C 1 124 ? 107.086 172.770 94.253  1.00 121.64 ? 124 ALA C N   1 
ATOM   10158 C CA  . ALA C 1 124 ? 107.550 172.322 92.941  1.00 120.87 ? 124 ALA C CA  1 
ATOM   10159 C C   . ALA C 1 124 ? 108.781 171.406 93.030  1.00 121.28 ? 124 ALA C C   1 
ATOM   10160 O O   . ALA C 1 124 ? 108.792 170.328 92.438  1.00 121.76 ? 124 ALA C O   1 
ATOM   10161 C CB  . ALA C 1 124 ? 107.851 173.554 92.078  1.00 118.81 ? 124 ALA C CB  1 
ATOM   10162 N N   . VAL C 1 125 ? 109.809 171.802 93.786  1.00 117.51 ? 125 VAL C N   1 
ATOM   10163 C CA  . VAL C 1 125 ? 111.066 171.042 93.927  1.00 115.15 ? 125 VAL C CA  1 
ATOM   10164 C C   . VAL C 1 125 ? 110.894 169.758 94.757  1.00 114.04 ? 125 VAL C C   1 
ATOM   10165 O O   . VAL C 1 125 ? 111.611 168.793 94.535  1.00 112.31 ? 125 VAL C O   1 
ATOM   10166 C CB  . VAL C 1 125 ? 112.181 171.947 94.491  1.00 112.88 ? 125 VAL C CB  1 
ATOM   10167 C CG1 . VAL C 1 125 ? 113.510 171.214 94.670  1.00 112.10 ? 125 VAL C CG1 1 
ATOM   10168 C CG2 . VAL C 1 125 ? 112.494 173.109 93.541  1.00 113.46 ? 125 VAL C CG2 1 
ATOM   10169 N N   . LEU C 1 126 ? 109.909 169.672 95.655  1.00 110.74 ? 126 LEU C N   1 
ATOM   10170 C CA  . LEU C 1 126 ? 109.541 168.414 96.322  1.00 109.87 ? 126 LEU C CA  1 
ATOM   10171 C C   . LEU C 1 126 ? 108.922 167.359 95.377  1.00 110.14 ? 126 LEU C C   1 
ATOM   10172 O O   . LEU C 1 126 ? 108.832 166.191 95.743  1.00 107.98 ? 126 LEU C O   1 
ATOM   10173 C CB  . LEU C 1 126 ? 108.583 168.735 97.486  1.00 105.33 ? 126 LEU C CB  1 
ATOM   10174 C CG  . LEU C 1 126 ? 109.274 169.392 98.688  1.00 106.27 ? 126 LEU C CG  1 
ATOM   10175 C CD1 . LEU C 1 126 ? 108.266 170.078 99.600  1.00 107.53 ? 126 LEU C CD1 1 
ATOM   10176 C CD2 . LEU C 1 126 ? 110.032 168.364 99.521  1.00 107.33 ? 126 LEU C CD2 1 
ATOM   10177 N N   . ASN C 1 127 ? 108.500 167.748 94.170  1.00 124.50 ? 127 ASN C N   1 
ATOM   10178 C CA  . ASN C 1 127 ? 107.750 166.926 93.214  1.00 123.54 ? 127 ASN C CA  1 
ATOM   10179 C C   . ASN C 1 127 ? 108.485 166.771 91.866  1.00 125.55 ? 127 ASN C C   1 
ATOM   10180 O O   . ASN C 1 127 ? 107.886 166.869 90.799  1.00 123.84 ? 127 ASN C O   1 
ATOM   10181 C CB  . ASN C 1 127 ? 106.321 167.486 93.099  1.00 123.17 ? 127 ASN C CB  1 
ATOM   10182 C CG  . ASN C 1 127 ? 105.504 167.198 94.343  1.00 125.85 ? 127 ASN C CG  1 
ATOM   10183 O OD1 . ASN C 1 127 ? 105.090 166.075 94.586  1.00 124.45 ? 127 ASN C OD1 1 
ATOM   10184 N ND2 . ASN C 1 127 ? 105.238 168.174 95.171  1.00 124.09 ? 127 ASN C ND2 1 
ATOM   10185 N N   . LEU C 1 128 ? 109.800 166.518 91.883  1.00 132.52 ? 128 LEU C N   1 
ATOM   10186 C CA  . LEU C 1 128 ? 110.573 166.221 90.666  1.00 132.24 ? 128 LEU C CA  1 
ATOM   10187 C C   . LEU C 1 128 ? 110.140 164.887 90.036  1.00 131.85 ? 128 LEU C C   1 
ATOM   10188 O O   . LEU C 1 128 ? 109.891 163.909 90.739  1.00 128.96 ? 128 LEU C O   1 
ATOM   10189 C CB  . LEU C 1 128 ? 112.089 166.184 90.940  1.00 130.45 ? 128 LEU C CB  1 
ATOM   10190 C CG  . LEU C 1 128 ? 112.692 167.406 91.643  1.00 130.22 ? 128 LEU C CG  1 
ATOM   10191 C CD1 . LEU C 1 128 ? 114.206 167.282 91.694  1.00 130.25 ? 128 LEU C CD1 1 
ATOM   10192 C CD2 . LEU C 1 128 ? 112.357 168.725 90.957  1.00 129.16 ? 128 LEU C CD2 1 
ATOM   10193 N N   . GLN C 1 129 ? 110.094 164.832 88.708  1.00 141.99 ? 129 GLN C N   1 
ATOM   10194 C CA  . GLN C 1 129 ? 109.743 163.650 87.917  1.00 141.88 ? 129 GLN C CA  1 
ATOM   10195 C C   . GLN C 1 129 ? 110.952 163.258 87.062  1.00 140.30 ? 129 GLN C C   1 
ATOM   10196 O O   . GLN C 1 129 ? 111.449 164.063 86.277  1.00 138.60 ? 129 GLN C O   1 
ATOM   10197 C CB  . GLN C 1 129 ? 108.503 163.966 87.061  1.00 139.52 ? 129 GLN C CB  1 
ATOM   10198 C CG  . GLN C 1 129 ? 107.260 164.273 87.920  1.00 138.05 ? 129 GLN C CG  1 
ATOM   10199 C CD  . GLN C 1 129 ? 106.088 164.863 87.137  1.00 138.72 ? 129 GLN C CD  1 
ATOM   10200 O OE1 . GLN C 1 129 ? 106.130 165.092 85.938  1.00 139.49 ? 129 GLN C OE1 1 
ATOM   10201 N NE2 . GLN C 1 129 ? 104.986 165.142 87.794  1.00 139.78 ? 129 GLN C NE2 1 
ATOM   10202 N N   . ASP C 1 130 ? 111.479 162.043 87.234  1.00 137.80 ? 130 ASP C N   1 
ATOM   10203 C CA  . ASP C 1 130 ? 112.703 161.599 86.551  1.00 138.01 ? 130 ASP C CA  1 
ATOM   10204 C C   . ASP C 1 130 ? 113.907 162.556 86.713  1.00 138.26 ? 130 ASP C C   1 
ATOM   10205 O O   . ASP C 1 130 ? 114.751 162.672 85.829  1.00 137.58 ? 130 ASP C O   1 
ATOM   10206 C CB  . ASP C 1 130 ? 112.388 161.299 85.084  1.00 136.25 ? 130 ASP C CB  1 
ATOM   10207 N N   . GLY C 1 131 ? 113.981 163.262 87.849  1.00 135.36 ? 131 GLY C N   1 
ATOM   10208 C CA  . GLY C 1 131 ? 115.048 164.211 88.191  1.00 135.09 ? 131 GLY C CA  1 
ATOM   10209 C C   . GLY C 1 131 ? 114.778 165.695 87.907  1.00 135.03 ? 131 GLY C C   1 
ATOM   10210 O O   . GLY C 1 131 ? 115.620 166.513 88.273  1.00 135.96 ? 131 GLY C O   1 
ATOM   10211 N N   . VAL C 1 132 ? 113.644 166.082 87.303  1.00 137.66 ? 132 VAL C N   1 
ATOM   10212 C CA  . VAL C 1 132 ? 113.308 167.498 86.998  1.00 139.14 ? 132 VAL C CA  1 
ATOM   10213 C C   . VAL C 1 132 ? 111.799 167.793 87.095  1.00 138.94 ? 132 VAL C C   1 
ATOM   10214 O O   . VAL C 1 132 ? 110.977 166.904 86.914  1.00 135.51 ? 132 VAL C O   1 
ATOM   10215 C CB  . VAL C 1 132 ? 113.889 167.883 85.620  1.00 137.58 ? 132 VAL C CB  1 
ATOM   10216 C CG1 . VAL C 1 132 ? 113.187 167.198 84.446  1.00 136.89 ? 132 VAL C CG1 1 
ATOM   10217 C CG2 . VAL C 1 132 ? 113.869 169.393 85.374  1.00 134.85 ? 132 VAL C CG2 1 
ATOM   10218 N N   . ASN C 1 133 ? 111.400 169.034 87.394  1.00 140.41 ? 133 ASN C N   1 
ATOM   10219 C CA  . ASN C 1 133 ? 110.007 169.495 87.286  1.00 139.62 ? 133 ASN C CA  1 
ATOM   10220 C C   . ASN C 1 133 ? 109.910 170.617 86.239  1.00 140.53 ? 133 ASN C C   1 
ATOM   10221 O O   . ASN C 1 133 ? 110.516 171.677 86.397  1.00 139.82 ? 133 ASN C O   1 
ATOM   10222 C CB  . ASN C 1 133 ? 109.497 169.915 88.679  1.00 139.92 ? 133 ASN C CB  1 
ATOM   10223 C CG  . ASN C 1 133 ? 108.045 170.373 88.711  1.00 140.80 ? 133 ASN C CG  1 
ATOM   10224 O OD1 . ASN C 1 133 ? 107.461 170.753 87.709  1.00 139.21 ? 133 ASN C OD1 1 
ATOM   10225 N ND2 . ASN C 1 133 ? 107.420 170.362 89.862  1.00 141.10 ? 133 ASN C ND2 1 
ATOM   10226 N N   . ALA C 1 134 ? 109.119 170.411 85.185  1.00 146.12 ? 134 ALA C N   1 
ATOM   10227 C CA  . ALA C 1 134 ? 108.980 171.359 84.079  1.00 145.08 ? 134 ALA C CA  1 
ATOM   10228 C C   . ALA C 1 134 ? 108.350 172.713 84.472  1.00 146.79 ? 134 ALA C C   1 
ATOM   10229 O O   . ALA C 1 134 ? 108.483 173.681 83.726  1.00 147.41 ? 134 ALA C O   1 
ATOM   10230 C CB  . ALA C 1 134 ? 108.175 170.671 82.970  1.00 145.31 ? 134 ALA C CB  1 
ATOM   10231 N N   . CYS C 1 135 ? 107.686 172.812 85.629  1.00 147.40 ? 135 CYS C N   1 
ATOM   10232 C CA  . CYS C 1 135 ? 107.089 174.059 86.110  1.00 147.28 ? 135 CYS C CA  1 
ATOM   10233 C C   . CYS C 1 135 ? 108.110 175.067 86.654  1.00 147.73 ? 135 CYS C C   1 
ATOM   10234 O O   . CYS C 1 135 ? 107.795 176.251 86.707  1.00 146.85 ? 135 CYS C O   1 
ATOM   10235 C CB  . CYS C 1 135 ? 106.050 173.758 87.198  1.00 148.22 ? 135 CYS C CB  1 
ATOM   10236 S SG  . CYS C 1 135 ? 104.797 172.610 86.580  1.00 153.08 ? 135 CYS C SG  1 
ATOM   10237 N N   . ILE C 1 136 ? 109.309 174.647 87.074  1.00 143.94 ? 136 ILE C N   1 
ATOM   10238 C CA  . ILE C 1 136 ? 110.252 175.536 87.781  1.00 142.28 ? 136 ILE C CA  1 
ATOM   10239 C C   . ILE C 1 136 ? 110.704 176.701 86.892  1.00 141.35 ? 136 ILE C C   1 
ATOM   10240 O O   . ILE C 1 136 ? 110.611 177.852 87.302  1.00 142.51 ? 136 ILE C O   1 
ATOM   10241 C CB  . ILE C 1 136 ? 111.452 174.744 88.346  1.00 142.23 ? 136 ILE C CB  1 
ATOM   10242 C CG1 . ILE C 1 136 ? 110.987 173.773 89.451  1.00 141.43 ? 136 ILE C CG1 1 
ATOM   10243 C CG2 . ILE C 1 136 ? 112.521 175.696 88.911  1.00 143.53 ? 136 ILE C CG2 1 
ATOM   10244 C CD1 . ILE C 1 136 ? 112.033 172.707 89.778  1.00 138.36 ? 136 ILE C CD1 1 
ATOM   10245 N N   . MET C 1 137 ? 111.140 176.432 85.658  1.00 146.40 ? 137 MET C N   1 
ATOM   10246 C CA  . MET C 1 137 ? 111.580 177.478 84.730  1.00 147.62 ? 137 MET C CA  1 
ATOM   10247 C C   . MET C 1 137 ? 110.487 178.548 84.468  1.00 147.80 ? 137 MET C C   1 
ATOM   10248 O O   . MET C 1 137 ? 110.760 179.726 84.698  1.00 146.53 ? 137 MET C O   1 
ATOM   10249 C CB  . MET C 1 137 ? 112.148 176.828 83.458  1.00 145.69 ? 137 MET C CB  1 
ATOM   10250 C CG  . MET C 1 137 ? 112.745 177.812 82.447  1.00 146.93 ? 137 MET C CG  1 
ATOM   10251 S SD  . MET C 1 137 ? 114.369 178.497 82.883  1.00 148.85 ? 137 MET C SD  1 
ATOM   10252 C CE  . MET C 1 137 ? 113.899 180.102 83.565  1.00 145.66 ? 137 MET C CE  1 
ATOM   10253 N N   . PRO C 1 138 ? 109.241 178.208 84.075  1.00 149.59 ? 138 PRO C N   1 
ATOM   10254 C CA  . PRO C 1 138 ? 108.189 179.210 83.935  1.00 148.21 ? 138 PRO C CA  1 
ATOM   10255 C C   . PRO C 1 138 ? 107.752 179.829 85.272  1.00 148.44 ? 138 PRO C C   1 
ATOM   10256 O O   . PRO C 1 138 ? 107.500 181.026 85.294  1.00 149.82 ? 138 PRO C O   1 
ATOM   10257 C CB  . PRO C 1 138 ? 107.038 178.524 83.196  1.00 147.27 ? 138 PRO C CB  1 
ATOM   10258 C CG  . PRO C 1 138 ? 107.262 177.040 83.449  1.00 148.03 ? 138 PRO C CG  1 
ATOM   10259 C CD  . PRO C 1 138 ? 108.777 176.924 83.573  1.00 148.93 ? 138 PRO C CD  1 
ATOM   10260 N N   . LEU C 1 139 ? 107.718 179.100 86.393  1.00 142.98 ? 139 LEU C N   1 
ATOM   10261 C CA  . LEU C 1 139 ? 107.393 179.685 87.705  1.00 143.79 ? 139 LEU C CA  1 
ATOM   10262 C C   . LEU C 1 139 ? 108.402 180.778 88.105  1.00 145.49 ? 139 LEU C C   1 
ATOM   10263 O O   . LEU C 1 139 ? 108.019 181.849 88.577  1.00 144.35 ? 139 LEU C O   1 
ATOM   10264 C CB  . LEU C 1 139 ? 107.334 178.556 88.751  1.00 145.17 ? 139 LEU C CB  1 
ATOM   10265 C CG  . LEU C 1 139 ? 106.923 178.999 90.162  1.00 144.61 ? 139 LEU C CG  1 
ATOM   10266 C CD1 . LEU C 1 139 ? 105.441 179.362 90.222  1.00 145.06 ? 139 LEU C CD1 1 
ATOM   10267 C CD2 . LEU C 1 139 ? 107.180 177.865 91.150  1.00 143.86 ? 139 LEU C CD2 1 
ATOM   10268 N N   . LEU C 1 140 ? 109.693 180.542 87.862  1.00 144.75 ? 140 LEU C N   1 
ATOM   10269 C CA  . LEU C 1 140 ? 110.742 181.534 88.078  1.00 143.51 ? 140 LEU C CA  1 
ATOM   10270 C C   . LEU C 1 140 ? 110.645 182.712 87.101  1.00 142.89 ? 140 LEU C C   1 
ATOM   10271 O O   . LEU C 1 140 ? 110.802 183.854 87.524  1.00 141.53 ? 140 LEU C O   1 
ATOM   10272 C CB  . LEU C 1 140 ? 112.118 180.848 88.025  1.00 142.77 ? 140 LEU C CB  1 
ATOM   10273 C CG  . LEU C 1 140 ? 112.379 179.883 89.194  1.00 141.61 ? 140 LEU C CG  1 
ATOM   10274 C CD1 . LEU C 1 140 ? 113.766 179.261 89.059  1.00 140.75 ? 140 LEU C CD1 1 
ATOM   10275 C CD2 . LEU C 1 140 ? 112.305 180.597 90.538  1.00 140.49 ? 140 LEU C CD2 1 
ATOM   10276 N N   . GLN C 1 141 ? 110.250 182.462 85.860  1.00 150.71 ? 141 GLN C N   1 
ATOM   10277 C CA  . GLN C 1 141 ? 110.027 183.644 84.993  1.00 150.64 ? 141 GLN C CA  1 
ATOM   10278 C C   . GLN C 1 141 ? 108.853 184.432 85.582  1.00 149.63 ? 141 GLN C C   1 
ATOM   10279 O O   . GLN C 1 141 ? 109.004 185.650 85.775  1.00 148.30 ? 141 GLN C O   1 
ATOM   10280 C CB  . GLN C 1 141 ? 109.742 183.246 83.549  1.00 149.54 ? 141 GLN C CB  1 
ATOM   10281 C CG  . GLN C 1 141 ? 109.864 184.419 82.588  1.00 149.72 ? 141 GLN C CG  1 
ATOM   10282 C CD  . GLN C 1 141 ? 110.970 185.360 82.999  1.00 150.41 ? 141 GLN C CD  1 
ATOM   10283 O OE1 . GLN C 1 141 ? 112.142 185.133 82.709  1.00 149.60 ? 141 GLN C OE1 1 
ATOM   10284 N NE2 . GLN C 1 141 ? 110.605 186.431 83.683  1.00 150.90 ? 141 GLN C NE2 1 
ATOM   10285 N N   . ILE C 1 142 ? 107.741 183.755 85.881  1.00 153.00 ? 142 ILE C N   1 
ATOM   10286 C CA  . ILE C 1 142 ? 106.543 184.437 86.391  1.00 152.98 ? 142 ILE C CA  1 
ATOM   10287 C C   . ILE C 1 142 ? 106.886 185.324 87.599  1.00 154.53 ? 142 ILE C C   1 
ATOM   10288 O O   . ILE C 1 142 ? 106.451 186.471 87.651  1.00 153.98 ? 142 ILE C O   1 
ATOM   10289 C CB  . ILE C 1 142 ? 105.436 183.405 86.701  1.00 152.92 ? 142 ILE C CB  1 
ATOM   10290 C CG1 . ILE C 1 142 ? 104.887 182.820 85.380  1.00 152.57 ? 142 ILE C CG1 1 
ATOM   10291 C CG2 . ILE C 1 142 ? 104.291 184.029 87.516  1.00 153.69 ? 142 ILE C CG2 1 
ATOM   10292 C CD1 . ILE C 1 142 ? 104.134 181.495 85.530  1.00 153.33 ? 142 ILE C CD1 1 
ATOM   10293 N N   . ASP C 1 143 ? 107.714 184.858 88.537  1.00 154.73 ? 143 ASP C N   1 
ATOM   10294 C CA  . ASP C 1 143 ? 108.207 185.697 89.638  1.00 153.23 ? 143 ASP C CA  1 
ATOM   10295 C C   . ASP C 1 143 ? 109.038 186.889 89.128  1.00 154.47 ? 143 ASP C C   1 
ATOM   10296 O O   . ASP C 1 143 ? 108.838 188.033 89.540  1.00 153.45 ? 143 ASP C O   1 
ATOM   10297 C CB  . ASP C 1 143 ? 109.052 184.845 90.593  1.00 153.44 ? 143 ASP C CB  1 
ATOM   10298 C CG  . ASP C 1 143 ? 109.521 185.658 91.806  1.00 155.55 ? 143 ASP C CG  1 
ATOM   10299 O OD1 . ASP C 1 143 ? 108.657 186.263 92.474  1.00 155.48 ? 143 ASP C OD1 1 
ATOM   10300 O OD2 . ASP C 1 143 ? 110.738 185.660 92.097  1.00 154.75 ? 143 ASP C OD2 1 
ATOM   10301 N N   . LYS C 1 144 ? 109.948 186.626 88.182  1.00 151.74 ? 144 LYS C N   1 
ATOM   10302 C CA  . LYS C 1 144 ? 110.832 187.615 87.549  1.00 150.34 ? 144 LYS C CA  1 
ATOM   10303 C C   . LYS C 1 144 ? 110.050 188.684 86.770  1.00 151.39 ? 144 LYS C C   1 
ATOM   10304 O O   . LYS C 1 144 ? 110.373 189.864 86.854  1.00 151.82 ? 144 LYS C O   1 
ATOM   10305 C CB  . LYS C 1 144 ? 111.813 186.825 86.669  1.00 152.16 ? 144 LYS C CB  1 
ATOM   10306 C CG  . LYS C 1 144 ? 113.028 187.595 86.137  1.00 152.01 ? 144 LYS C CG  1 
ATOM   10307 C CD  . LYS C 1 144 ? 113.899 186.711 85.223  1.00 151.56 ? 144 LYS C CD  1 
ATOM   10308 C CE  . LYS C 1 144 ? 114.472 185.470 85.928  1.00 150.89 ? 144 LYS C CE  1 
ATOM   10309 N NZ  . LYS C 1 144 ? 115.151 184.544 84.991  1.00 149.51 ? 144 LYS C NZ  1 
ATOM   10310 N N   . ASP C 1 145 ? 108.982 188.284 86.078  1.00 157.74 ? 145 ASP C N   1 
ATOM   10311 C CA  . ASP C 1 145 ? 108.038 189.175 85.387  1.00 157.63 ? 145 ASP C CA  1 
ATOM   10312 C C   . ASP C 1 145 ? 107.057 189.883 86.336  1.00 156.89 ? 145 ASP C C   1 
ATOM   10313 O O   . ASP C 1 145 ? 106.531 190.942 85.983  1.00 157.15 ? 145 ASP C O   1 
ATOM   10314 C CB  . ASP C 1 145 ? 107.248 188.383 84.331  1.00 158.64 ? 145 ASP C CB  1 
ATOM   10315 C CG  . ASP C 1 145 ? 108.065 187.970 83.098  1.00 158.71 ? 145 ASP C CG  1 
ATOM   10316 O OD1 . ASP C 1 145 ? 109.166 188.520 82.875  1.00 157.97 ? 145 ASP C OD1 1 
ATOM   10317 O OD2 . ASP C 1 145 ? 107.561 187.155 82.293  1.00 157.87 ? 145 ASP C OD2 1 
ATOM   10318 N N   . SER C 1 146 ? 106.802 189.348 87.535  1.00 158.29 ? 146 SER C N   1 
ATOM   10319 C CA  . SER C 1 146 ? 105.963 190.019 88.536  1.00 158.17 ? 146 SER C CA  1 
ATOM   10320 C C   . SER C 1 146 ? 106.661 191.191 89.243  1.00 158.81 ? 146 SER C C   1 
ATOM   10321 O O   . SER C 1 146 ? 105.987 191.972 89.915  1.00 157.61 ? 146 SER C O   1 
ATOM   10322 C CB  . SER C 1 146 ? 105.475 189.007 89.572  1.00 158.57 ? 146 SER C CB  1 
ATOM   10323 O OG  . SER C 1 146 ? 104.501 189.600 90.405  1.00 159.70 ? 146 SER C OG  1 
ATOM   10324 N N   . GLY C 1 147 ? 107.987 191.332 89.134  1.00 158.88 ? 147 GLY C N   1 
ATOM   10325 C CA  . GLY C 1 147 ? 108.721 192.478 89.693  1.00 158.02 ? 147 GLY C CA  1 
ATOM   10326 C C   . GLY C 1 147 ? 108.922 192.405 91.214  1.00 160.54 ? 147 GLY C C   1 
ATOM   10327 O O   . GLY C 1 147 ? 108.953 193.429 91.899  1.00 160.31 ? 147 GLY C O   1 
ATOM   10328 N N   . ASN C 1 148 ? 109.037 191.187 91.740  1.00 159.29 ? 148 ASN C N   1 
ATOM   10329 C CA  . ASN C 1 148 ? 109.132 190.902 93.166  1.00 158.45 ? 148 ASN C CA  1 
ATOM   10330 C C   . ASN C 1 148 ? 110.417 191.489 93.805  1.00 157.37 ? 148 ASN C C   1 
ATOM   10331 O O   . ASN C 1 148 ? 111.514 191.201 93.319  1.00 155.82 ? 148 ASN C O   1 
ATOM   10332 C CB  . ASN C 1 148 ? 109.057 189.373 93.289  1.00 157.11 ? 148 ASN C CB  1 
ATOM   10333 C CG  . ASN C 1 148 ? 108.950 188.867 94.711  1.00 157.07 ? 148 ASN C CG  1 
ATOM   10334 O OD1 . ASN C 1 148 ? 109.089 189.597 95.679  1.00 156.93 ? 148 ASN C OD1 1 
ATOM   10335 N ND2 . ASN C 1 148 ? 108.701 187.599 94.879  1.00 156.91 ? 148 ASN C ND2 1 
ATOM   10336 N N   . PRO C 1 149 ? 110.332 192.258 94.910  1.00 161.42 ? 149 PRO C N   1 
ATOM   10337 C CA  . PRO C 1 149 ? 111.503 192.757 95.639  1.00 161.62 ? 149 PRO C CA  1 
ATOM   10338 C C   . PRO C 1 149 ? 112.216 191.690 96.498  1.00 161.52 ? 149 PRO C C   1 
ATOM   10339 O O   . PRO C 1 149 ? 113.333 191.928 96.957  1.00 159.60 ? 149 PRO C O   1 
ATOM   10340 C CB  . PRO C 1 149 ? 110.963 193.901 96.507  1.00 161.48 ? 149 PRO C CB  1 
ATOM   10341 C CG  . PRO C 1 149 ? 109.527 193.478 96.792  1.00 160.59 ? 149 PRO C CG  1 
ATOM   10342 C CD  . PRO C 1 149 ? 109.110 192.799 95.490  1.00 161.28 ? 149 PRO C CD  1 
ATOM   10343 N N   . LYS C 1 150 ? 111.596 190.527 96.732  1.00 158.02 ? 150 LYS C N   1 
ATOM   10344 C CA  . LYS C 1 150 ? 112.108 189.416 97.555  1.00 155.96 ? 150 LYS C CA  1 
ATOM   10345 C C   . LYS C 1 150 ? 112.013 188.105 96.770  1.00 155.84 ? 150 LYS C C   1 
ATOM   10346 O O   . LYS C 1 150 ? 111.034 187.370 96.914  1.00 157.75 ? 150 LYS C O   1 
ATOM   10347 C CB  . LYS C 1 150 ? 111.327 189.355 98.883  1.00 155.30 ? 150 LYS C CB  1 
ATOM   10348 C CG  . LYS C 1 150 ? 111.528 190.597 99.760  1.00 155.45 ? 150 LYS C CG  1 
ATOM   10349 C CD  . LYS C 1 150 ? 110.740 190.476 101.066 1.00 156.08 ? 150 LYS C CD  1 
ATOM   10350 C CE  . LYS C 1 150 ? 110.918 191.744 101.901 1.00 156.02 ? 150 LYS C CE  1 
ATOM   10351 N NZ  . LYS C 1 150 ? 110.152 191.682 103.164 1.00 155.32 ? 150 LYS C NZ  1 
ATOM   10352 N N   . LEU C 1 151 ? 112.994 187.864 95.897  1.00 143.35 ? 151 LEU C N   1 
ATOM   10353 C CA  . LEU C 1 151 ? 112.977 186.838 94.842  1.00 144.81 ? 151 LEU C CA  1 
ATOM   10354 C C   . LEU C 1 151 ? 112.632 185.428 95.350  1.00 144.41 ? 151 LEU C C   1 
ATOM   10355 O O   . LEU C 1 151 ? 113.118 184.997 96.395  1.00 143.26 ? 151 LEU C O   1 
ATOM   10356 C CB  . LEU C 1 151 ? 114.340 186.800 94.124  1.00 145.81 ? 151 LEU C CB  1 
ATOM   10357 C CG  . LEU C 1 151 ? 114.620 187.931 93.121  1.00 146.15 ? 151 LEU C CG  1 
ATOM   10358 C CD1 . LEU C 1 151 ? 114.785 189.302 93.771  1.00 145.18 ? 151 LEU C CD1 1 
ATOM   10359 C CD2 . LEU C 1 151 ? 115.904 187.618 92.356  1.00 143.70 ? 151 LEU C CD2 1 
ATOM   10360 N N   . LEU C 1 152 ? 111.856 184.675 94.565  1.00 137.85 ? 152 LEU C N   1 
ATOM   10361 C CA  . LEU C 1 152 ? 111.306 183.369 94.943  1.00 136.04 ? 152 LEU C CA  1 
ATOM   10362 C C   . LEU C 1 152 ? 112.366 182.293 95.239  1.00 137.06 ? 152 LEU C C   1 
ATOM   10363 O O   . LEU C 1 152 ? 112.154 181.446 96.100  1.00 136.54 ? 152 LEU C O   1 
ATOM   10364 C CB  . LEU C 1 152 ? 110.310 182.960 93.845  1.00 134.88 ? 152 LEU C CB  1 
ATOM   10365 C CG  . LEU C 1 152 ? 109.594 181.619 94.040  1.00 134.74 ? 152 LEU C CG  1 
ATOM   10366 C CD1 . LEU C 1 152 ? 108.753 181.581 95.313  1.00 136.00 ? 152 LEU C CD1 1 
ATOM   10367 C CD2 . LEU C 1 152 ? 108.670 181.370 92.855  1.00 136.24 ? 152 LEU C CD2 1 
ATOM   10368 N N   . VAL C 1 153 ? 113.529 182.347 94.584  1.00 126.65 ? 153 VAL C N   1 
ATOM   10369 C CA  . VAL C 1 153 ? 114.664 181.451 94.870  1.00 125.69 ? 153 VAL C CA  1 
ATOM   10370 C C   . VAL C 1 153 ? 115.327 181.706 96.228  1.00 124.44 ? 153 VAL C C   1 
ATOM   10371 O O   . VAL C 1 153 ? 115.893 180.782 96.804  1.00 121.37 ? 153 VAL C O   1 
ATOM   10372 C CB  . VAL C 1 153 ? 115.746 181.528 93.777  1.00 122.44 ? 153 VAL C CB  1 
ATOM   10373 C CG1 . VAL C 1 153 ? 115.312 180.797 92.515  1.00 122.21 ? 153 VAL C CG1 1 
ATOM   10374 C CG2 . VAL C 1 153 ? 116.144 182.955 93.394  1.00 123.10 ? 153 VAL C CG2 1 
ATOM   10375 N N   . ASN C 1 154 ? 115.251 182.935 96.749  1.00 126.90 ? 154 ASN C N   1 
ATOM   10376 C CA  . ASN C 1 154 ? 115.906 183.350 97.996  1.00 124.79 ? 154 ASN C CA  1 
ATOM   10377 C C   . ASN C 1 154 ? 114.954 183.404 99.201  1.00 125.40 ? 154 ASN C C   1 
ATOM   10378 O O   . ASN C 1 154 ? 115.407 183.601 100.330 1.00 124.10 ? 154 ASN C O   1 
ATOM   10379 C CB  . ASN C 1 154 ? 116.634 184.689 97.769  1.00 125.09 ? 154 ASN C CB  1 
ATOM   10380 C CG  . ASN C 1 154 ? 117.757 184.597 96.757  1.00 128.03 ? 154 ASN C CG  1 
ATOM   10381 O OD1 . ASN C 1 154 ? 118.313 183.542 96.508  1.00 127.90 ? 154 ASN C OD1 1 
ATOM   10382 N ND2 . ASN C 1 154 ? 118.125 185.688 96.132  1.00 125.61 ? 154 ASN C ND2 1 
ATOM   10383 N N   . ALA C 1 155 ? 113.649 183.222 98.996  1.00 120.74 ? 155 ALA C N   1 
ATOM   10384 C CA  . ALA C 1 155 ? 112.683 183.056 100.073 1.00 117.07 ? 155 ALA C CA  1 
ATOM   10385 C C   . ALA C 1 155 ? 112.907 181.738 100.828 1.00 116.86 ? 155 ALA C C   1 
ATOM   10386 O O   . ALA C 1 155 ? 113.315 180.728 100.254 1.00 115.10 ? 155 ALA C O   1 
ATOM   10387 C CB  . ALA C 1 155 ? 111.274 183.151 99.496  1.00 117.54 ? 155 ALA C CB  1 
ATOM   10388 N N   . GLN C 1 156 ? 112.633 181.754 102.130 1.00 109.47 ? 156 GLN C N   1 
ATOM   10389 C CA  . GLN C 1 156 ? 112.976 180.683 103.065 1.00 107.57 ? 156 GLN C CA  1 
ATOM   10390 C C   . GLN C 1 156 ? 111.810 180.388 104.019 1.00 109.07 ? 156 GLN C C   1 
ATOM   10391 O O   . GLN C 1 156 ? 110.973 181.253 104.269 1.00 109.42 ? 156 GLN C O   1 
ATOM   10392 C CB  . GLN C 1 156 ? 114.197 181.097 103.897 1.00 106.83 ? 156 GLN C CB  1 
ATOM   10393 C CG  . GLN C 1 156 ? 115.494 181.398 103.126 1.00 109.33 ? 156 GLN C CG  1 
ATOM   10394 C CD  . GLN C 1 156 ? 116.233 182.582 103.746 1.00 109.30 ? 156 GLN C CD  1 
ATOM   10395 O OE1 . GLN C 1 156 ? 116.695 182.537 104.874 1.00 105.67 ? 156 GLN C OE1 1 
ATOM   10396 N NE2 . GLN C 1 156 ? 116.353 183.690 103.051 1.00 109.69 ? 156 GLN C NE2 1 
ATOM   10397 N N   . CYS C 1 157 ? 111.783 179.192 104.610 1.00 104.52 ? 157 CYS C N   1 
ATOM   10398 C CA  . CYS C 1 157 ? 110.896 178.896 105.728 1.00 104.85 ? 157 CYS C CA  1 
ATOM   10399 C C   . CYS C 1 157 ? 111.250 179.758 106.956 1.00 106.96 ? 157 CYS C C   1 
ATOM   10400 O O   . CYS C 1 157 ? 112.395 180.187 107.110 1.00 108.34 ? 157 CYS C O   1 
ATOM   10401 C CB  . CYS C 1 157 ? 110.961 177.397 106.018 1.00 102.25 ? 157 CYS C CB  1 
ATOM   10402 S SG  . CYS C 1 157 ? 110.400 176.468 104.569 1.00 99.88  ? 157 CYS C SG  1 
ATOM   10403 N N   . THR C 1 158 ? 110.275 180.034 107.826 1.00 112.36 ? 158 THR C N   1 
ATOM   10404 C CA  . THR C 1 158 ? 110.354 181.082 108.867 1.00 111.55 ? 158 THR C CA  1 
ATOM   10405 C C   . THR C 1 158 ? 110.008 180.609 110.284 1.00 108.66 ? 158 THR C C   1 
ATOM   10406 O O   . THR C 1 158 ? 110.220 181.349 111.242 1.00 104.49 ? 158 THR C O   1 
ATOM   10407 C CB  . THR C 1 158 ? 109.412 182.240 108.511 1.00 112.21 ? 158 THR C CB  1 
ATOM   10408 O OG1 . THR C 1 158 ? 108.114 181.742 108.299 1.00 114.13 ? 158 THR C OG1 1 
ATOM   10409 C CG2 . THR C 1 158 ? 109.825 182.987 107.256 1.00 108.92 ? 158 THR C CG2 1 
ATOM   10410 N N   . ASP C 1 159 ? 109.470 179.404 110.455 1.00 110.87 ? 159 ASP C N   1 
ATOM   10411 C CA  . ASP C 1 159 ? 109.102 178.847 111.762 1.00 108.99 ? 159 ASP C CA  1 
ATOM   10412 C C   . ASP C 1 159 ? 110.325 178.347 112.548 1.00 107.91 ? 159 ASP C C   1 
ATOM   10413 O O   . ASP C 1 159 ? 111.384 178.099 111.985 1.00 110.10 ? 159 ASP C O   1 
ATOM   10414 C CB  . ASP C 1 159 ? 108.119 177.699 111.547 1.00 109.06 ? 159 ASP C CB  1 
ATOM   10415 C CG  . ASP C 1 159 ? 108.752 176.604 110.693 1.00 113.11 ? 159 ASP C CG  1 
ATOM   10416 O OD1 . ASP C 1 159 ? 108.685 176.727 109.446 1.00 113.61 ? 159 ASP C OD1 1 
ATOM   10417 O OD2 . ASP C 1 159 ? 109.340 175.676 111.290 1.00 114.25 ? 159 ASP C OD2 1 
ATOM   10418 N N   . GLU C 1 160 ? 110.188 178.157 113.859 1.00 103.65 ? 160 GLU C N   1 
ATOM   10419 C CA  . GLU C 1 160 ? 111.313 177.829 114.739 1.00 102.68 ? 160 GLU C CA  1 
ATOM   10420 C C   . GLU C 1 160 ? 112.024 176.503 114.422 1.00 103.79 ? 160 GLU C C   1 
ATOM   10421 O O   . GLU C 1 160 ? 113.168 176.330 114.841 1.00 104.89 ? 160 GLU C O   1 
ATOM   10422 C CB  . GLU C 1 160 ? 110.863 177.882 116.212 1.00 102.33 ? 160 GLU C CB  1 
ATOM   10423 C CG  . GLU C 1 160 ? 109.937 176.751 116.702 1.00 106.11 ? 160 GLU C CG  1 
ATOM   10424 C CD  . GLU C 1 160 ? 108.465 176.857 116.257 1.00 109.91 ? 160 GLU C CD  1 
ATOM   10425 O OE1 . GLU C 1 160 ? 108.057 177.892 115.680 1.00 110.06 ? 160 GLU C OE1 1 
ATOM   10426 O OE2 . GLU C 1 160 ? 107.701 175.903 116.521 1.00 105.25 ? 160 GLU C OE2 1 
ATOM   10427 N N   . PHE C 1 161 ? 111.403 175.572 113.693 1.00 91.18  ? 161 PHE C N   1 
ATOM   10428 C CA  . PHE C 1 161 ? 112.043 174.321 113.288 1.00 91.65  ? 161 PHE C CA  1 
ATOM   10429 C C   . PHE C 1 161 ? 112.732 174.430 111.936 1.00 92.34  ? 161 PHE C C   1 
ATOM   10430 O O   . PHE C 1 161 ? 113.892 174.039 111.836 1.00 91.63  ? 161 PHE C O   1 
ATOM   10431 C CB  . PHE C 1 161 ? 111.039 173.172 113.308 1.00 87.64  ? 161 PHE C CB  1 
ATOM   10432 C CG  . PHE C 1 161 ? 110.777 172.655 114.702 1.00 92.97  ? 161 PHE C CG  1 
ATOM   10433 C CD1 . PHE C 1 161 ? 111.672 171.737 115.278 1.00 93.75  ? 161 PHE C CD1 1 
ATOM   10434 C CD2 . PHE C 1 161 ? 109.660 173.091 115.430 1.00 93.11  ? 161 PHE C CD2 1 
ATOM   10435 C CE1 . PHE C 1 161 ? 111.448 171.254 116.574 1.00 92.63  ? 161 PHE C CE1 1 
ATOM   10436 C CE2 . PHE C 1 161 ? 109.429 172.600 116.726 1.00 94.15  ? 161 PHE C CE2 1 
ATOM   10437 C CZ  . PHE C 1 161 ? 110.322 171.679 117.296 1.00 96.67  ? 161 PHE C CZ  1 
ATOM   10438 N N   . TYR C 1 162 ? 112.083 174.983 110.916 1.00 94.28  ? 162 TYR C N   1 
ATOM   10439 C CA  . TYR C 1 162 ? 112.615 174.992 109.551 1.00 92.67  ? 162 TYR C CA  1 
ATOM   10440 C C   . TYR C 1 162 ? 113.203 176.337 109.108 1.00 95.07  ? 162 TYR C C   1 
ATOM   10441 O O   . TYR C 1 162 ? 113.477 176.513 107.927 1.00 99.54  ? 162 TYR C O   1 
ATOM   10442 C CB  . TYR C 1 162 ? 111.584 174.428 108.564 1.00 90.67  ? 162 TYR C CB  1 
ATOM   10443 C CG  . TYR C 1 162 ? 111.048 173.074 108.988 1.00 91.91  ? 162 TYR C CG  1 
ATOM   10444 C CD1 . TYR C 1 162 ? 111.894 171.949 108.972 1.00 92.59  ? 162 TYR C CD1 1 
ATOM   10445 C CD2 . TYR C 1 162 ? 109.738 172.953 109.482 1.00 91.98  ? 162 TYR C CD2 1 
ATOM   10446 C CE1 . TYR C 1 162 ? 111.443 170.720 109.482 1.00 93.00  ? 162 TYR C CE1 1 
ATOM   10447 C CE2 . TYR C 1 162 ? 109.288 171.726 110.004 1.00 92.47  ? 162 TYR C CE2 1 
ATOM   10448 C CZ  . TYR C 1 162 ? 110.150 170.613 110.022 1.00 90.55  ? 162 TYR C CZ  1 
ATOM   10449 O OH  . TYR C 1 162 ? 109.742 169.444 110.566 1.00 85.47  ? 162 TYR C OH  1 
ATOM   10450 N N   . GLN C 1 163 ? 113.439 177.290 110.013 1.00 100.78 ? 163 GLN C N   1 
ATOM   10451 C CA  . GLN C 1 163 ? 113.935 178.622 109.655 1.00 98.90  ? 163 GLN C CA  1 
ATOM   10452 C C   . GLN C 1 163 ? 115.142 178.579 108.709 1.00 96.90  ? 163 GLN C C   1 
ATOM   10453 O O   . GLN C 1 163 ? 116.106 177.847 108.936 1.00 99.36  ? 163 GLN C O   1 
ATOM   10454 C CB  . GLN C 1 163 ? 114.257 179.444 110.911 1.00 98.73  ? 163 GLN C CB  1 
ATOM   10455 C CG  . GLN C 1 163 ? 114.536 180.914 110.580 1.00 98.27  ? 163 GLN C CG  1 
ATOM   10456 C CD  . GLN C 1 163 ? 114.568 181.801 111.822 1.00 104.39 ? 163 GLN C CD  1 
ATOM   10457 O OE1 . GLN C 1 163 ? 114.587 181.352 112.957 1.00 103.48 ? 163 GLN C OE1 1 
ATOM   10458 N NE2 . GLN C 1 163 ? 114.591 183.101 111.653 1.00 101.68 ? 163 GLN C NE2 1 
ATOM   10459 N N   . GLY C 1 164 ? 115.096 179.365 107.638 1.00 90.97  ? 164 GLY C N   1 
ATOM   10460 C CA  . GLY C 1 164 ? 116.187 179.482 106.673 1.00 90.65  ? 164 GLY C CA  1 
ATOM   10461 C C   . GLY C 1 164 ? 116.269 178.353 105.642 1.00 90.74  ? 164 GLY C C   1 
ATOM   10462 O O   . GLY C 1 164 ? 117.051 178.451 104.700 1.00 94.62  ? 164 GLY C O   1 
ATOM   10463 N N   . HIS C 1 165 ? 115.467 177.296 105.774 1.00 81.84  ? 165 HIS C N   1 
ATOM   10464 C CA  . HIS C 1 165 ? 115.348 176.245 104.758 1.00 79.65  ? 165 HIS C CA  1 
ATOM   10465 C C   . HIS C 1 165 ? 114.854 176.817 103.433 1.00 80.81  ? 165 HIS C C   1 
ATOM   10466 O O   . HIS C 1 165 ? 113.959 177.662 103.421 1.00 89.34  ? 165 HIS C O   1 
ATOM   10467 C CB  . HIS C 1 165 ? 114.387 175.174 105.257 1.00 86.54  ? 165 HIS C CB  1 
ATOM   10468 C CG  . HIS C 1 165 ? 114.247 173.995 104.344 1.00 89.59  ? 165 HIS C CG  1 
ATOM   10469 N ND1 . HIS C 1 165 ? 115.307 173.300 103.779 1.00 88.03  ? 165 HIS C ND1 1 
ATOM   10470 C CD2 . HIS C 1 165 ? 113.083 173.369 104.027 1.00 89.53  ? 165 HIS C CD2 1 
ATOM   10471 C CE1 . HIS C 1 165 ? 114.758 172.275 103.117 1.00 84.91  ? 165 HIS C CE1 1 
ATOM   10472 N NE2 . HIS C 1 165 ? 113.425 172.288 103.254 1.00 83.44  ? 165 HIS C NE2 1 
ATOM   10473 N N   . SER C 1 166 ? 115.418 176.378 102.315 1.00 79.39  ? 166 SER C N   1 
ATOM   10474 C CA  . SER C 1 166 ? 115.174 176.971 100.999 1.00 85.41  ? 166 SER C CA  1 
ATOM   10475 C C   . SER C 1 166 ? 115.017 175.912 99.920  1.00 86.49  ? 166 SER C C   1 
ATOM   10476 O O   . SER C 1 166 ? 115.420 174.762 100.082 1.00 89.31  ? 166 SER C O   1 
ATOM   10477 C CB  . SER C 1 166 ? 116.291 177.955 100.625 1.00 90.27  ? 166 SER C CB  1 
ATOM   10478 O OG  . SER C 1 166 ? 117.419 177.286 100.096 1.00 86.54  ? 166 SER C OG  1 
ATOM   10479 N N   . ALA C 1 167 ? 114.465 176.302 98.775  1.00 92.26  ? 167 ALA C N   1 
ATOM   10480 C CA  . ALA C 1 167 ? 114.310 175.408 97.627  1.00 94.42  ? 167 ALA C CA  1 
ATOM   10481 C C   . ALA C 1 167 ? 115.635 174.766 97.180  1.00 94.30  ? 167 ALA C C   1 
ATOM   10482 O O   . ALA C 1 167 ? 115.634 173.620 96.737  1.00 95.55  ? 167 ALA C O   1 
ATOM   10483 C CB  . ALA C 1 167 ? 113.670 176.207 96.496  1.00 94.13  ? 167 ALA C CB  1 
ATOM   10484 N N   . LEU C 1 168 ? 116.771 175.462 97.318  1.00 89.54  ? 168 LEU C N   1 
ATOM   10485 C CA  . LEU C 1 168 ? 118.090 174.913 96.994  1.00 91.67  ? 168 LEU C CA  1 
ATOM   10486 C C   . LEU C 1 168 ? 118.501 173.789 97.956  1.00 91.84  ? 168 LEU C C   1 
ATOM   10487 O O   . LEU C 1 168 ? 118.975 172.751 97.509  1.00 97.16  ? 168 LEU C O   1 
ATOM   10488 C CB  . LEU C 1 168 ? 119.110 176.064 96.940  1.00 90.57  ? 168 LEU C CB  1 
ATOM   10489 C CG  . LEU C 1 168 ? 120.555 175.645 96.619  1.00 89.02  ? 168 LEU C CG  1 
ATOM   10490 C CD1 . LEU C 1 168 ? 120.687 174.953 95.264  1.00 87.42  ? 168 LEU C CD1 1 
ATOM   10491 C CD2 . LEU C 1 168 ? 121.451 176.875 96.588  1.00 90.92  ? 168 LEU C CD2 1 
ATOM   10492 N N   . HIS C 1 169 ? 118.240 173.911 99.260  1.00 76.73  ? 169 HIS C N   1 
ATOM   10493 C CA  . HIS C 1 169 ? 118.443 172.799 100.193 1.00 76.54  ? 169 HIS C CA  1 
ATOM   10494 C C   . HIS C 1 169 ? 117.524 171.603 99.898  1.00 82.99  ? 169 HIS C C   1 
ATOM   10495 O O   . HIS C 1 169 ? 117.911 170.458 100.125 1.00 83.80  ? 169 HIS C O   1 
ATOM   10496 C CB  . HIS C 1 169 ? 118.220 173.259 101.631 1.00 76.35  ? 169 HIS C CB  1 
ATOM   10497 C CG  . HIS C 1 169 ? 119.087 174.390 102.102 1.00 77.51  ? 169 HIS C CG  1 
ATOM   10498 N ND1 . HIS C 1 169 ? 118.809 175.743 101.938 1.00 80.17  ? 169 HIS C ND1 1 
ATOM   10499 C CD2 . HIS C 1 169 ? 120.203 174.257 102.873 1.00 78.61  ? 169 HIS C CD2 1 
ATOM   10500 C CE1 . HIS C 1 169 ? 119.759 176.394 102.622 1.00 79.00  ? 169 HIS C CE1 1 
ATOM   10501 N NE2 . HIS C 1 169 ? 120.606 175.527 103.191 1.00 80.70  ? 169 HIS C NE2 1 
ATOM   10502 N N   . ILE C 1 170 ? 116.313 171.825 99.379  1.00 91.77  ? 170 ILE C N   1 
ATOM   10503 C CA  . ILE C 1 170 ? 115.438 170.734 98.922  1.00 91.30  ? 170 ILE C CA  1 
ATOM   10504 C C   . ILE C 1 170 ? 116.034 170.073 97.680  1.00 93.97  ? 170 ILE C C   1 
ATOM   10505 O O   . ILE C 1 170 ? 116.155 168.852 97.633  1.00 96.47  ? 170 ILE C O   1 
ATOM   10506 C CB  . ILE C 1 170 ? 113.993 171.208 98.658  1.00 86.38  ? 170 ILE C CB  1 
ATOM   10507 C CG1 . ILE C 1 170 ? 113.382 171.849 99.915  1.00 87.13  ? 170 ILE C CG1 1 
ATOM   10508 C CG2 . ILE C 1 170 ? 113.110 170.032 98.219  1.00 86.64  ? 170 ILE C CG2 1 
ATOM   10509 C CD1 . ILE C 1 170 ? 112.008 172.468 99.688  1.00 89.82  ? 170 ILE C CD1 1 
ATOM   10510 N N   . ALA C 1 171 ? 116.458 170.860 96.694  1.00 89.33  ? 171 ALA C N   1 
ATOM   10511 C CA  . ALA C 1 171 ? 117.046 170.357 95.455  1.00 84.50  ? 171 ALA C CA  1 
ATOM   10512 C C   . ALA C 1 171 ? 118.284 169.483 95.701  1.00 87.18  ? 171 ALA C C   1 
ATOM   10513 O O   . ALA C 1 171 ? 118.459 168.451 95.056  1.00 88.64  ? 171 ALA C O   1 
ATOM   10514 C CB  . ALA C 1 171 ? 117.389 171.556 94.571  1.00 82.21  ? 171 ALA C CB  1 
ATOM   10515 N N   . ILE C 1 172 ? 119.137 169.873 96.646  1.00 87.94  ? 172 ILE C N   1 
ATOM   10516 C CA  . ILE C 1 172 ? 120.329 169.106 96.998  1.00 82.72  ? 172 ILE C CA  1 
ATOM   10517 C C   . ILE C 1 172 ? 119.953 167.834 97.760  1.00 85.10  ? 172 ILE C C   1 
ATOM   10518 O O   . ILE C 1 172 ? 120.474 166.774 97.434  1.00 86.36  ? 172 ILE C O   1 
ATOM   10519 C CB  . ILE C 1 172 ? 121.335 169.978 97.769  1.00 79.10  ? 172 ILE C CB  1 
ATOM   10520 C CG1 . ILE C 1 172 ? 121.811 171.155 96.898  1.00 82.87  ? 172 ILE C CG1 1 
ATOM   10521 C CG2 . ILE C 1 172 ? 122.559 169.153 98.188  1.00 82.80  ? 172 ILE C CG2 1 
ATOM   10522 C CD1 . ILE C 1 172 ? 122.451 172.279 97.691  1.00 81.25  ? 172 ILE C CD1 1 
ATOM   10523 N N   . GLU C 1 173 ? 119.034 167.866 98.728  1.00 92.57  ? 173 GLU C N   1 
ATOM   10524 C CA  . GLU C 1 173 ? 118.650 166.643 99.450  1.00 90.29  ? 173 GLU C CA  1 
ATOM   10525 C C   . GLU C 1 173 ? 117.939 165.628 98.551  1.00 93.68  ? 173 GLU C C   1 
ATOM   10526 O O   . GLU C 1 173 ? 118.217 164.434 98.642  1.00 95.59  ? 173 GLU C O   1 
ATOM   10527 C CB  . GLU C 1 173 ? 117.799 166.985 100.675 1.00 92.49  ? 173 GLU C CB  1 
ATOM   10528 C CG  . GLU C 1 173 ? 117.513 165.761 101.566 1.00 95.30  ? 173 GLU C CG  1 
ATOM   10529 C CD  . GLU C 1 173 ? 116.337 164.865 101.120 1.00 100.14 ? 173 GLU C CD  1 
ATOM   10530 O OE1 . GLU C 1 173 ? 115.428 165.322 100.389 1.00 100.32 ? 173 GLU C OE1 1 
ATOM   10531 O OE2 . GLU C 1 173 ? 116.303 163.691 101.555 1.00 97.34  ? 173 GLU C OE2 1 
ATOM   10532 N N   . LYS C 1 174 ? 117.101 166.094 97.620  1.00 97.20  ? 174 LYS C N   1 
ATOM   10533 C CA  . LYS C 1 174 ? 116.479 165.291 96.550  1.00 95.22  ? 174 LYS C CA  1 
ATOM   10534 C C   . LYS C 1 174 ? 117.475 164.825 95.471  1.00 98.04  ? 174 LYS C C   1 
ATOM   10535 O O   . LYS C 1 174 ? 117.075 164.150 94.525  1.00 95.82  ? 174 LYS C O   1 
ATOM   10536 C CB  . LYS C 1 174 ? 115.301 166.086 95.957  1.00 94.13  ? 174 LYS C CB  1 
ATOM   10537 C CG  . LYS C 1 174 ? 114.143 166.276 96.953  1.00 97.35  ? 174 LYS C CG  1 
ATOM   10538 C CD  . LYS C 1 174 ? 113.319 164.999 97.152  1.00 99.27  ? 174 LYS C CD  1 
ATOM   10539 C CE  . LYS C 1 174 ? 112.332 165.117 98.319  1.00 99.54  ? 174 LYS C CE  1 
ATOM   10540 N NZ  . LYS C 1 174 ? 112.904 164.625 99.595  1.00 95.09  ? 174 LYS C NZ  1 
ATOM   10541 N N   . ARG C 1 175 ? 118.767 165.150 95.593  1.00 96.20  ? 175 ARG C N   1 
ATOM   10542 C CA  . ARG C 1 175 ? 119.891 164.724 94.732  1.00 90.42  ? 175 ARG C CA  1 
ATOM   10543 C C   . ARG C 1 175 ? 119.824 165.152 93.260  1.00 91.77  ? 175 ARG C C   1 
ATOM   10544 O O   . ARG C 1 175 ? 120.449 164.519 92.409  1.00 92.66  ? 175 ARG C O   1 
ATOM   10545 C CB  . ARG C 1 175 ? 120.178 163.216 94.874  1.00 93.04  ? 175 ARG C CB  1 
ATOM   10546 C CG  . ARG C 1 175 ? 120.354 162.740 96.315  1.00 92.08  ? 175 ARG C CG  1 
ATOM   10547 C CD  . ARG C 1 175 ? 120.702 161.248 96.370  1.00 91.61  ? 175 ARG C CD  1 
ATOM   10548 N NE  . ARG C 1 175 ? 122.052 160.952 95.850  1.00 99.96  ? 175 ARG C NE  1 
ATOM   10549 C CZ  . ARG C 1 175 ? 123.191 161.056 96.504  1.00 97.15  ? 175 ARG C CZ  1 
ATOM   10550 N NH1 . ARG C 1 175 ? 124.309 160.702 95.947  1.00 91.31  ? 175 ARG C NH1 1 
ATOM   10551 N NH2 . ARG C 1 175 ? 123.229 161.514 97.717  1.00 92.60  ? 175 ARG C NH2 1 
ATOM   10552 N N   . SER C 1 176 ? 119.078 166.201 92.919  1.00 106.64 ? 176 SER C N   1 
ATOM   10553 C CA  . SER C 1 176 ? 118.958 166.646 91.524  1.00 108.42 ? 176 SER C CA  1 
ATOM   10554 C C   . SER C 1 176 ? 119.984 167.721 91.175  1.00 107.17 ? 176 SER C C   1 
ATOM   10555 O O   . SER C 1 176 ? 119.762 168.911 91.399  1.00 108.10 ? 176 SER C O   1 
ATOM   10556 C CB  . SER C 1 176 ? 117.537 167.110 91.214  1.00 108.72 ? 176 SER C CB  1 
ATOM   10557 O OG  . SER C 1 176 ? 117.488 167.579 89.877  1.00 109.80 ? 176 SER C OG  1 
ATOM   10558 N N   . LEU C 1 177 ? 121.095 167.324 90.549  1.00 108.37 ? 177 LEU C N   1 
ATOM   10559 C CA  . LEU C 1 177 ? 122.046 168.274 89.966  1.00 111.60 ? 177 LEU C CA  1 
ATOM   10560 C C   . LEU C 1 177 ? 121.367 169.170 88.922  1.00 110.50 ? 177 LEU C C   1 
ATOM   10561 O O   . LEU C 1 177 ? 121.653 170.360 88.852  1.00 112.12 ? 177 LEU C O   1 
ATOM   10562 C CB  . LEU C 1 177 ? 123.228 167.500 89.357  1.00 112.46 ? 177 LEU C CB  1 
ATOM   10563 C CG  . LEU C 1 177 ? 124.260 168.387 88.633  1.00 109.51 ? 177 LEU C CG  1 
ATOM   10564 C CD1 . LEU C 1 177 ? 124.978 169.338 89.587  1.00 108.01 ? 177 LEU C CD1 1 
ATOM   10565 C CD2 . LEU C 1 177 ? 125.308 167.515 87.951  1.00 107.01 ? 177 LEU C CD2 1 
ATOM   10566 N N   . GLN C 1 178 ? 120.433 168.625 88.137  1.00 114.56 ? 178 GLN C N   1 
ATOM   10567 C CA  . GLN C 1 178 ? 119.682 169.378 87.133  1.00 114.35 ? 178 GLN C CA  1 
ATOM   10568 C C   . GLN C 1 178 ? 118.865 170.513 87.767  1.00 113.36 ? 178 GLN C C   1 
ATOM   10569 O O   . GLN C 1 178 ? 118.834 171.623 87.236  1.00 112.43 ? 178 GLN C O   1 
ATOM   10570 C CB  . GLN C 1 178 ? 118.752 168.427 86.357  1.00 113.21 ? 178 GLN C CB  1 
ATOM   10571 C CG  . GLN C 1 178 ? 119.471 167.494 85.367  1.00 114.33 ? 178 GLN C CG  1 
ATOM   10572 C CD  . GLN C 1 178 ? 120.234 166.326 85.986  1.00 114.82 ? 178 GLN C CD  1 
ATOM   10573 O OE1 . GLN C 1 178 ? 120.084 165.970 87.148  1.00 113.79 ? 178 GLN C OE1 1 
ATOM   10574 N NE2 . GLN C 1 178 ? 121.092 165.679 85.236  1.00 113.85 ? 178 GLN C NE2 1 
ATOM   10575 N N   . CYS C 1 179 ? 118.247 170.271 88.922  1.00 111.40 ? 179 CYS C N   1 
ATOM   10576 C CA  . CYS C 1 179 ? 117.501 171.295 89.635  1.00 110.65 ? 179 CYS C CA  1 
ATOM   10577 C C   . CYS C 1 179 ? 118.429 172.290 90.358  1.00 113.97 ? 179 CYS C C   1 
ATOM   10578 O O   . CYS C 1 179 ? 118.177 173.493 90.307  1.00 112.97 ? 179 CYS C O   1 
ATOM   10579 C CB  . CYS C 1 179 ? 116.511 170.596 90.566  1.00 112.86 ? 179 CYS C CB  1 
ATOM   10580 S SG  . CYS C 1 179 ? 115.304 171.810 91.135  1.00 122.79 ? 179 CYS C SG  1 
ATOM   10581 N N   . VAL C 1 180 ? 119.548 171.839 90.943  1.00 106.09 ? 180 VAL C N   1 
ATOM   10582 C CA  . VAL C 1 180 ? 120.563 172.743 91.520  1.00 104.52 ? 180 VAL C CA  1 
ATOM   10583 C C   . VAL C 1 180 ? 121.077 173.731 90.478  1.00 105.26 ? 180 VAL C C   1 
ATOM   10584 O O   . VAL C 1 180 ? 121.063 174.936 90.713  1.00 103.82 ? 180 VAL C O   1 
ATOM   10585 C CB  . VAL C 1 180 ? 121.727 171.957 92.139  1.00 102.29 ? 180 VAL C CB  1 
ATOM   10586 C CG1 . VAL C 1 180 ? 122.907 172.856 92.508  1.00 105.33 ? 180 VAL C CG1 1 
ATOM   10587 C CG2 . VAL C 1 180 ? 121.268 171.260 93.413  1.00 101.61 ? 180 VAL C CG2 1 
ATOM   10588 N N   . LYS C 1 181 ? 121.463 173.238 89.299  1.00 111.00 ? 181 LYS C N   1 
ATOM   10589 C CA  . LYS C 1 181 ? 121.844 174.079 88.162  1.00 107.80 ? 181 LYS C CA  1 
ATOM   10590 C C   . LYS C 1 181 ? 120.739 175.078 87.813  1.00 111.09 ? 181 LYS C C   1 
ATOM   10591 O O   . LYS C 1 181 ? 120.999 176.271 87.763  1.00 110.43 ? 181 LYS C O   1 
ATOM   10592 C CB  . LYS C 1 181 ? 122.170 173.200 86.946  1.00 105.16 ? 181 LYS C CB  1 
ATOM   10593 C CG  . LYS C 1 181 ? 123.509 172.474 87.101  1.00 110.28 ? 181 LYS C CG  1 
ATOM   10594 C CD  . LYS C 1 181 ? 123.786 171.573 85.896  1.00 111.07 ? 181 LYS C CD  1 
ATOM   10595 C CE  . LYS C 1 181 ? 125.202 171.003 85.965  1.00 111.96 ? 181 LYS C CE  1 
ATOM   10596 N NZ  . LYS C 1 181 ? 125.532 170.232 84.746  1.00 108.69 ? 181 LYS C NZ  1 
ATOM   10597 N N   . LEU C 1 182 ? 119.502 174.627 87.600  1.00 117.54 ? 182 LEU C N   1 
ATOM   10598 C CA  . LEU C 1 182 ? 118.391 175.505 87.226  1.00 114.53 ? 182 LEU C CA  1 
ATOM   10599 C C   . LEU C 1 182 ? 118.134 176.625 88.255  1.00 116.08 ? 182 LEU C C   1 
ATOM   10600 O O   . LEU C 1 182 ? 117.869 177.768 87.879  1.00 116.84 ? 182 LEU C O   1 
ATOM   10601 C CB  . LEU C 1 182 ? 117.150 174.619 87.007  1.00 116.23 ? 182 LEU C CB  1 
ATOM   10602 C CG  . LEU C 1 182 ? 115.866 175.370 86.623  1.00 117.58 ? 182 LEU C CG  1 
ATOM   10603 C CD1 . LEU C 1 182 ? 116.004 176.135 85.312  1.00 116.56 ? 182 LEU C CD1 1 
ATOM   10604 C CD2 . LEU C 1 182 ? 114.730 174.367 86.453  1.00 115.41 ? 182 LEU C CD2 1 
ATOM   10605 N N   . LEU C 1 183 ? 118.224 176.320 89.549  1.00 108.77 ? 183 LEU C N   1 
ATOM   10606 C CA  . LEU C 1 183 ? 118.065 177.298 90.625  1.00 110.13 ? 183 LEU C CA  1 
ATOM   10607 C C   . LEU C 1 183 ? 119.226 178.301 90.676  1.00 111.60 ? 183 LEU C C   1 
ATOM   10608 O O   . LEU C 1 183 ? 118.992 179.508 90.728  1.00 108.26 ? 183 LEU C O   1 
ATOM   10609 C CB  . LEU C 1 183 ? 117.941 176.551 91.965  1.00 110.15 ? 183 LEU C CB  1 
ATOM   10610 C CG  . LEU C 1 183 ? 116.626 175.779 92.152  1.00 106.70 ? 183 LEU C CG  1 
ATOM   10611 C CD1 . LEU C 1 183 ? 116.741 174.886 93.380  1.00 106.17 ? 183 LEU C CD1 1 
ATOM   10612 C CD2 . LEU C 1 183 ? 115.450 176.726 92.372  1.00 110.44 ? 183 LEU C CD2 1 
ATOM   10613 N N   . VAL C 1 184 ? 120.473 177.824 90.648  1.00 115.57 ? 184 VAL C N   1 
ATOM   10614 C CA  . VAL C 1 184 ? 121.670 178.680 90.718  1.00 112.66 ? 184 VAL C CA  1 
ATOM   10615 C C   . VAL C 1 184 ? 121.827 179.545 89.462  1.00 112.23 ? 184 VAL C C   1 
ATOM   10616 O O   . VAL C 1 184 ? 122.155 180.726 89.572  1.00 113.04 ? 184 VAL C O   1 
ATOM   10617 C CB  . VAL C 1 184 ? 122.919 177.824 90.989  1.00 109.50 ? 184 VAL C CB  1 
ATOM   10618 C CG1 . VAL C 1 184 ? 124.219 178.624 90.890  1.00 111.27 ? 184 VAL C CG1 1 
ATOM   10619 C CG2 . VAL C 1 184 ? 122.875 177.223 92.397  1.00 111.41 ? 184 VAL C CG2 1 
ATOM   10620 N N   . GLU C 1 185 ? 121.507 179.025 88.275  1.00 113.59 ? 185 GLU C N   1 
ATOM   10621 C CA  . GLU C 1 185 ? 121.446 179.810 87.030  1.00 114.89 ? 185 GLU C CA  1 
ATOM   10622 C C   . GLU C 1 185 ? 120.433 180.963 87.108  1.00 118.09 ? 185 GLU C C   1 
ATOM   10623 O O   . GLU C 1 185 ? 120.663 182.029 86.541  1.00 119.45 ? 185 GLU C O   1 
ATOM   10624 C CB  . GLU C 1 185 ? 121.074 178.892 85.855  1.00 115.29 ? 185 GLU C CB  1 
ATOM   10625 C CG  . GLU C 1 185 ? 122.249 178.009 85.409  1.00 117.19 ? 185 GLU C CG  1 
ATOM   10626 C CD  . GLU C 1 185 ? 121.857 176.880 84.437  1.00 119.55 ? 185 GLU C CD  1 
ATOM   10627 O OE1 . GLU C 1 185 ? 120.738 176.888 83.877  1.00 119.23 ? 185 GLU C OE1 1 
ATOM   10628 O OE2 . GLU C 1 185 ? 122.707 175.999 84.178  1.00 118.53 ? 185 GLU C OE2 1 
ATOM   10629 N N   . ASN C 1 186 ? 119.327 180.787 87.834  1.00 121.38 ? 186 ASN C N   1 
ATOM   10630 C CA  . ASN C 1 186 ? 118.342 181.840 88.099  1.00 120.53 ? 186 ASN C CA  1 
ATOM   10631 C C   . ASN C 1 186 ? 118.645 182.685 89.351  1.00 120.44 ? 186 ASN C C   1 
ATOM   10632 O O   . ASN C 1 186 ? 117.817 183.498 89.764  1.00 117.17 ? 186 ASN C O   1 
ATOM   10633 C CB  . ASN C 1 186 ? 116.942 181.216 88.088  1.00 120.06 ? 186 ASN C CB  1 
ATOM   10634 C CG  . ASN C 1 186 ? 116.496 180.958 86.664  1.00 122.07 ? 186 ASN C CG  1 
ATOM   10635 O OD1 . ASN C 1 186 ? 116.036 181.860 85.974  1.00 124.20 ? 186 ASN C OD1 1 
ATOM   10636 N ND2 . ASN C 1 186 ? 116.641 179.749 86.179  1.00 121.19 ? 186 ASN C ND2 1 
ATOM   10637 N N   . GLY C 1 187 ? 119.839 182.551 89.933  1.00 117.40 ? 187 GLY C N   1 
ATOM   10638 C CA  . GLY C 1 187 ? 120.324 183.424 91.007  1.00 115.80 ? 187 GLY C CA  1 
ATOM   10639 C C   . GLY C 1 187 ? 119.977 182.990 92.433  1.00 116.56 ? 187 GLY C C   1 
ATOM   10640 O O   . GLY C 1 187 ? 119.983 183.835 93.327  1.00 113.65 ? 187 GLY C O   1 
ATOM   10641 N N   . ALA C 1 188 ? 119.678 181.709 92.662  1.00 115.74 ? 188 ALA C N   1 
ATOM   10642 C CA  . ALA C 1 188 ? 119.501 181.176 94.011  1.00 116.09 ? 188 ALA C CA  1 
ATOM   10643 C C   . ALA C 1 188 ? 120.773 181.350 94.849  1.00 114.51 ? 188 ALA C C   1 
ATOM   10644 O O   . ALA C 1 188 ? 121.840 180.881 94.457  1.00 115.47 ? 188 ALA C O   1 
ATOM   10645 C CB  . ALA C 1 188 ? 119.120 179.696 93.929  1.00 116.02 ? 188 ALA C CB  1 
ATOM   10646 N N   . ASP C 1 189 ? 120.671 182.020 95.994  1.00 112.26 ? 189 ASP C N   1 
ATOM   10647 C CA  . ASP C 1 189 ? 121.821 182.318 96.841  1.00 112.03 ? 189 ASP C CA  1 
ATOM   10648 C C   . ASP C 1 189 ? 122.415 181.041 97.455  1.00 114.47 ? 189 ASP C C   1 
ATOM   10649 O O   . ASP C 1 189 ? 121.812 180.374 98.294  1.00 113.04 ? 189 ASP C O   1 
ATOM   10650 C CB  . ASP C 1 189 ? 121.449 183.371 97.891  1.00 110.14 ? 189 ASP C CB  1 
ATOM   10651 C CG  . ASP C 1 189 ? 122.605 183.732 98.838  1.00 113.47 ? 189 ASP C CG  1 
ATOM   10652 O OD1 . ASP C 1 189 ? 123.768 183.361 98.561  1.00 115.63 ? 189 ASP C OD1 1 
ATOM   10653 O OD2 . ASP C 1 189 ? 122.345 184.440 99.834  1.00 113.24 ? 189 ASP C OD2 1 
ATOM   10654 N N   . VAL C 1 190 ? 123.630 180.704 97.041  1.00 104.43 ? 190 VAL C N   1 
ATOM   10655 C CA  . VAL C 1 190 ? 124.373 179.520 97.472  1.00 99.99  ? 190 VAL C CA  1 
ATOM   10656 C C   . VAL C 1 190 ? 124.780 179.576 98.952  1.00 101.91 ? 190 VAL C C   1 
ATOM   10657 O O   . VAL C 1 190 ? 125.167 178.554 99.509  1.00 102.62 ? 190 VAL C O   1 
ATOM   10658 C CB  . VAL C 1 190 ? 125.570 179.337 96.518  1.00 99.69  ? 190 VAL C CB  1 
ATOM   10659 C CG1 . VAL C 1 190 ? 126.576 178.279 96.945  1.00 106.26 ? 190 VAL C CG1 1 
ATOM   10660 C CG2 . VAL C 1 190 ? 125.080 178.938 95.125  1.00 100.31 ? 190 VAL C CG2 1 
ATOM   10661 N N   . HIS C 1 191 ? 124.667 180.726 99.629  1.00 100.19 ? 191 HIS C N   1 
ATOM   10662 C CA  . HIS C 1 191 ? 125.081 180.899 101.027 1.00 97.99  ? 191 HIS C CA  1 
ATOM   10663 C C   . HIS C 1 191 ? 123.920 181.053 102.023 1.00 100.82 ? 191 HIS C C   1 
ATOM   10664 O O   . HIS C 1 191 ? 124.125 181.507 103.149 1.00 102.76 ? 191 HIS C O   1 
ATOM   10665 C CB  . HIS C 1 191 ? 126.111 182.032 101.148 1.00 102.28 ? 191 HIS C CB  1 
ATOM   10666 C CG  . HIS C 1 191 ? 127.348 181.824 100.313 1.00 105.24 ? 191 HIS C CG  1 
ATOM   10667 N ND1 . HIS C 1 191 ? 127.534 182.244 99.020  1.00 105.96 ? 191 HIS C ND1 1 
ATOM   10668 C CD2 . HIS C 1 191 ? 128.460 181.122 100.674 1.00 98.80  ? 191 HIS C CD2 1 
ATOM   10669 C CE1 . HIS C 1 191 ? 128.741 181.828 98.614  1.00 103.63 ? 191 HIS C CE1 1 
ATOM   10670 N NE2 . HIS C 1 191 ? 129.344 181.135 99.593  1.00 104.39 ? 191 HIS C NE2 1 
ATOM   10671 N N   . LEU C 1 192 ? 122.698 180.669 101.651 1.00 104.66 ? 192 LEU C N   1 
ATOM   10672 C CA  . LEU C 1 192 ? 121.546 180.629 102.561 1.00 99.15  ? 192 LEU C CA  1 
ATOM   10673 C C   . LEU C 1 192 ? 121.749 179.586 103.662 1.00 98.29  ? 192 LEU C C   1 
ATOM   10674 O O   . LEU C 1 192 ? 122.078 178.439 103.382 1.00 101.86 ? 192 LEU C O   1 
ATOM   10675 C CB  . LEU C 1 192 ? 120.268 180.300 101.769 1.00 99.90  ? 192 LEU C CB  1 
ATOM   10676 C CG  . LEU C 1 192 ? 119.859 181.383 100.771 1.00 103.85 ? 192 LEU C CG  1 
ATOM   10677 C CD1 . LEU C 1 192 ? 118.725 180.876 99.892  1.00 105.74 ? 192 LEU C CD1 1 
ATOM   10678 C CD2 . LEU C 1 192 ? 119.404 182.659 101.465 1.00 101.18 ? 192 LEU C CD2 1 
ATOM   10679 N N   . ARG C 1 193 ? 121.501 179.949 104.920 1.00 86.62  ? 193 ARG C N   1 
ATOM   10680 C CA  . ARG C 1 193 ? 121.677 179.055 106.069 1.00 87.74  ? 193 ARG C CA  1 
ATOM   10681 C C   . ARG C 1 193 ? 120.347 178.479 106.546 1.00 88.41  ? 193 ARG C C   1 
ATOM   10682 O O   . ARG C 1 193 ? 119.542 179.191 107.139 1.00 91.00  ? 193 ARG C O   1 
ATOM   10683 C CB  . ARG C 1 193 ? 122.473 179.781 107.155 1.00 88.57  ? 193 ARG C CB  1 
ATOM   10684 C CG  . ARG C 1 193 ? 123.964 179.839 106.865 1.00 91.53  ? 193 ARG C CG  1 
ATOM   10685 C CD  . ARG C 1 193 ? 124.609 181.178 107.144 1.00 91.76  ? 193 ARG C CD  1 
ATOM   10686 N NE  . ARG C 1 193 ? 124.545 181.534 108.550 1.00 98.65  ? 193 ARG C NE  1 
ATOM   10687 C CZ  . ARG C 1 193 ? 125.414 182.333 109.153 1.00 97.01  ? 193 ARG C CZ  1 
ATOM   10688 N NH1 . ARG C 1 193 ? 125.281 182.607 110.438 1.00 91.91  ? 193 ARG C NH1 1 
ATOM   10689 N NH2 . ARG C 1 193 ? 126.425 182.840 108.472 1.00 95.13  ? 193 ARG C NH2 1 
ATOM   10690 N N   . ALA C 1 194 ? 120.156 177.177 106.382 1.00 74.14  ? 194 ALA C N   1 
ATOM   10691 C CA  . ALA C 1 194 ? 119.080 176.423 107.008 1.00 72.72  ? 194 ALA C CA  1 
ATOM   10692 C C   . ALA C 1 194 ? 119.393 176.251 108.497 1.00 71.98  ? 194 ALA C C   1 
ATOM   10693 O O   . ALA C 1 194 ? 120.124 175.350 108.874 1.00 75.09  ? 194 ALA C O   1 
ATOM   10694 C CB  . ALA C 1 194 ? 118.958 175.088 106.277 1.00 76.24  ? 194 ALA C CB  1 
ATOM   10695 N N   . CYS C 1 195 ? 118.895 177.154 109.341 1.00 78.08  ? 195 CYS C N   1 
ATOM   10696 C CA  . CYS C 1 195 ? 119.390 177.371 110.704 1.00 79.85  ? 195 CYS C CA  1 
ATOM   10697 C C   . CYS C 1 195 ? 118.364 177.126 111.818 1.00 85.23  ? 195 CYS C C   1 
ATOM   10698 O O   . CYS C 1 195 ? 118.732 177.159 112.995 1.00 86.75  ? 195 CYS C O   1 
ATOM   10699 C CB  . CYS C 1 195 ? 119.970 178.789 110.782 1.00 83.99  ? 195 CYS C CB  1 
ATOM   10700 S SG  . CYS C 1 195 ? 118.788 180.048 110.223 1.00 87.60  ? 195 CYS C SG  1 
ATOM   10701 N N   . GLY C 1 196 ? 117.096 176.868 111.488 1.00 85.43  ? 196 GLY C N   1 
ATOM   10702 C CA  . GLY C 1 196 ? 116.059 176.505 112.454 1.00 79.17  ? 196 GLY C CA  1 
ATOM   10703 C C   . GLY C 1 196 ? 116.340 175.202 113.202 1.00 78.37  ? 196 GLY C C   1 
ATOM   10704 O O   . GLY C 1 196 ? 117.207 174.421 112.825 1.00 83.83  ? 196 GLY C O   1 
ATOM   10705 N N   . ARG C 1 197 ? 115.662 174.958 114.322 1.00 76.60  ? 197 ARG C N   1 
ATOM   10706 C CA  . ARG C 1 197 ? 115.991 173.831 115.248 1.00 77.20  ? 197 ARG C CA  1 
ATOM   10707 C C   . ARG C 1 197 ? 116.046 172.448 114.620 1.00 79.26  ? 197 ARG C C   1 
ATOM   10708 O O   . ARG C 1 197 ? 116.679 171.581 115.209 1.00 80.43  ? 197 ARG C O   1 
ATOM   10709 C CB  . ARG C 1 197 ? 114.984 173.794 116.396 1.00 77.59  ? 197 ARG C CB  1 
ATOM   10710 C CG  . ARG C 1 197 ? 115.408 172.950 117.587 1.00 81.56  ? 197 ARG C CG  1 
ATOM   10711 C CD  . ARG C 1 197 ? 116.105 173.785 118.639 1.00 80.78  ? 197 ARG C CD  1 
ATOM   10712 N NE  . ARG C 1 197 ? 117.512 173.438 118.746 1.00 87.10  ? 197 ARG C NE  1 
ATOM   10713 C CZ  . ARG C 1 197 ? 118.022 172.670 119.698 1.00 88.84  ? 197 ARG C CZ  1 
ATOM   10714 N NH1 . ARG C 1 197 ? 119.317 172.409 119.713 1.00 84.41  ? 197 ARG C NH1 1 
ATOM   10715 N NH2 . ARG C 1 197 ? 117.236 172.166 120.631 1.00 82.27  ? 197 ARG C NH2 1 
ATOM   10716 N N   . PHE C 1 198 ? 115.340 172.209 113.538 1.00 72.37  ? 198 PHE C N   1 
ATOM   10717 C CA  . PHE C 1 198 ? 115.480 170.910 112.881 1.00 72.09  ? 198 PHE C CA  1 
ATOM   10718 C C   . PHE C 1 198 ? 116.904 170.665 112.350 1.00 75.16  ? 198 PHE C C   1 
ATOM   10719 O O   . PHE C 1 198 ? 117.377 169.536 112.325 1.00 75.17  ? 198 PHE C O   1 
ATOM   10720 C CB  . PHE C 1 198 ? 114.448 170.825 111.756 1.00 68.52  ? 198 PHE C CB  1 
ATOM   10721 C CG  . PHE C 1 198 ? 114.537 169.555 110.948 1.00 72.76  ? 198 PHE C CG  1 
ATOM   10722 C CD1 . PHE C 1 198 ? 114.304 168.311 111.550 1.00 71.94  ? 198 PHE C CD1 1 
ATOM   10723 C CD2 . PHE C 1 198 ? 114.879 169.613 109.592 1.00 73.86  ? 198 PHE C CD2 1 
ATOM   10724 C CE1 . PHE C 1 198 ? 114.427 167.138 110.798 1.00 68.07  ? 198 PHE C CE1 1 
ATOM   10725 C CE2 . PHE C 1 198 ? 115.016 168.439 108.841 1.00 67.66  ? 198 PHE C CE2 1 
ATOM   10726 C CZ  . PHE C 1 198 ? 114.787 167.199 109.444 1.00 64.11  ? 198 PHE C CZ  1 
ATOM   10727 N N   . PHE C 1 199 ? 117.610 171.724 111.956 1.00 65.23  ? 199 PHE C N   1 
ATOM   10728 C CA  . PHE C 1 199 ? 118.945 171.670 111.366 1.00 59.33  ? 199 PHE C CA  1 
ATOM   10729 C C   . PHE C 1 199 ? 120.080 171.857 112.370 1.00 68.95  ? 199 PHE C C   1 
ATOM   10730 O O   . PHE C 1 199 ? 121.244 171.728 112.015 1.00 72.32  ? 199 PHE C O   1 
ATOM   10731 C CB  . PHE C 1 199 ? 119.037 172.745 110.296 1.00 62.27  ? 199 PHE C CB  1 
ATOM   10732 C CG  . PHE C 1 199 ? 117.919 172.674 109.293 1.00 65.12  ? 199 PHE C CG  1 
ATOM   10733 C CD1 . PHE C 1 199 ? 117.822 171.576 108.428 1.00 67.91  ? 199 PHE C CD1 1 
ATOM   10734 C CD2 . PHE C 1 199 ? 116.958 173.689 109.244 1.00 71.60  ? 199 PHE C CD2 1 
ATOM   10735 C CE1 . PHE C 1 199 ? 116.806 171.526 107.465 1.00 68.32  ? 199 PHE C CE1 1 
ATOM   10736 C CE2 . PHE C 1 199 ? 115.926 173.625 108.307 1.00 67.49  ? 199 PHE C CE2 1 
ATOM   10737 C CZ  . PHE C 1 199 ? 115.855 172.552 107.408 1.00 67.67  ? 199 PHE C CZ  1 
ATOM   10738 N N   . GLN C 1 200 ? 119.778 172.199 113.614 1.00 71.41  ? 200 GLN C N   1 
ATOM   10739 C CA  . GLN C 1 200 ? 120.746 172.260 114.700 1.00 66.74  ? 200 GLN C CA  1 
ATOM   10740 C C   . GLN C 1 200 ? 121.064 170.849 115.217 1.00 67.67  ? 200 GLN C C   1 
ATOM   10741 O O   . GLN C 1 200 ? 120.320 169.910 114.955 1.00 77.83  ? 200 GLN C O   1 
ATOM   10742 C CB  . GLN C 1 200 ? 120.193 173.183 115.790 1.00 72.76  ? 200 GLN C CB  1 
ATOM   10743 C CG  . GLN C 1 200 ? 120.017 174.622 115.268 1.00 77.16  ? 200 GLN C CG  1 
ATOM   10744 C CD  . GLN C 1 200 ? 119.341 175.547 116.266 1.00 76.01  ? 200 GLN C CD  1 
ATOM   10745 O OE1 . GLN C 1 200 ? 119.188 175.253 117.441 1.00 70.44  ? 200 GLN C OE1 1 
ATOM   10746 N NE2 . GLN C 1 200 ? 118.891 176.700 115.837 1.00 71.80  ? 200 GLN C NE2 1 
ATOM   10747 N N   . LYS C 1 201 ? 122.155 170.672 115.971 1.00 70.75  ? 201 LYS C N   1 
ATOM   10748 C CA  . LYS C 1 201 ? 122.522 169.373 116.552 1.00 74.95  ? 201 LYS C CA  1 
ATOM   10749 C C   . LYS C 1 201 ? 122.016 169.275 117.998 1.00 84.47  ? 201 LYS C C   1 
ATOM   10750 O O   . LYS C 1 201 ? 122.423 170.060 118.852 1.00 87.24  ? 201 LYS C O   1 
ATOM   10751 C CB  . LYS C 1 201 ? 124.043 169.196 116.437 1.00 79.85  ? 201 LYS C CB  1 
ATOM   10752 C CG  . LYS C 1 201 ? 124.494 167.774 116.787 1.00 81.24  ? 201 LYS C CG  1 
ATOM   10753 C CD  . LYS C 1 201 ? 126.017 167.652 116.763 1.00 83.23  ? 201 LYS C CD  1 
ATOM   10754 C CE  . LYS C 1 201 ? 126.446 166.266 117.253 1.00 82.05  ? 201 LYS C CE  1 
ATOM   10755 N NZ  . LYS C 1 201 ? 127.873 166.227 117.653 1.00 81.40  ? 201 LYS C NZ  1 
ATOM   10756 N N   . HIS C 1 202 ? 121.126 168.321 118.267 1.00 84.58  ? 202 HIS C N   1 
ATOM   10757 C CA  . HIS C 1 202 ? 120.499 168.063 119.570 1.00 77.58  ? 202 HIS C CA  1 
ATOM   10758 C C   . HIS C 1 202 ? 119.983 166.622 119.678 1.00 79.35  ? 202 HIS C C   1 
ATOM   10759 O O   . HIS C 1 202 ? 120.038 165.856 118.720 1.00 80.60  ? 202 HIS C O   1 
ATOM   10760 C CB  . HIS C 1 202 ? 119.401 169.099 119.841 1.00 78.58  ? 202 HIS C CB  1 
ATOM   10761 C CG  . HIS C 1 202 ? 118.248 169.096 118.878 1.00 82.19  ? 202 HIS C CG  1 
ATOM   10762 N ND1 . HIS C 1 202 ? 117.150 168.236 118.915 1.00 84.61  ? 202 HIS C ND1 1 
ATOM   10763 C CD2 . HIS C 1 202 ? 118.062 170.001 117.883 1.00 83.00  ? 202 HIS C CD2 1 
ATOM   10764 C CE1 . HIS C 1 202 ? 116.332 168.645 117.932 1.00 82.23  ? 202 HIS C CE1 1 
ATOM   10765 N NE2 . HIS C 1 202 ? 116.862 169.701 117.299 1.00 78.62  ? 202 HIS C NE2 1 
ATOM   10766 N N   . GLN C 1 203 ? 119.543 166.214 120.870 1.00 94.84  ? 203 GLN C N   1 
ATOM   10767 C CA  . GLN C 1 203 ? 119.118 164.844 121.170 1.00 98.01  ? 203 GLN C CA  1 
ATOM   10768 C C   . GLN C 1 203 ? 117.763 164.411 120.581 1.00 97.49  ? 203 GLN C C   1 
ATOM   10769 O O   . GLN C 1 203 ? 117.418 163.230 120.656 1.00 97.24  ? 203 GLN C O   1 
ATOM   10770 C CB  . GLN C 1 203 ? 119.085 164.705 122.690 1.00 91.59  ? 203 GLN C CB  1 
ATOM   10771 N N   . GLY C 1 204 ? 116.969 165.331 120.030 1.00 84.46  ? 204 GLY C N   1 
ATOM   10772 C CA  . GLY C 1 204 ? 115.663 165.067 119.422 1.00 84.08  ? 204 GLY C CA  1 
ATOM   10773 C C   . GLY C 1 204 ? 115.725 164.672 117.944 1.00 86.42  ? 204 GLY C C   1 
ATOM   10774 O O   . GLY C 1 204 ? 116.762 164.257 117.427 1.00 81.78  ? 204 GLY C O   1 
ATOM   10775 N N   . THR C 1 205 ? 114.609 164.876 117.247 1.00 87.90  ? 205 THR C N   1 
ATOM   10776 C CA  . THR C 1 205 ? 114.528 164.754 115.786 1.00 83.43  ? 205 THR C CA  1 
ATOM   10777 C C   . THR C 1 205 ? 115.213 165.944 115.124 1.00 87.97  ? 205 THR C C   1 
ATOM   10778 O O   . THR C 1 205 ? 114.722 167.068 115.193 1.00 85.36  ? 205 THR C O   1 
ATOM   10779 C CB  . THR C 1 205 ? 113.072 164.639 115.324 1.00 82.29  ? 205 THR C CB  1 
ATOM   10780 O OG1 . THR C 1 205 ? 112.501 163.486 115.884 1.00 82.33  ? 205 THR C OG1 1 
ATOM   10781 C CG2 . THR C 1 205 ? 112.938 164.492 113.818 1.00 81.23  ? 205 THR C CG2 1 
ATOM   10782 N N   . CYS C 1 206 ? 116.346 165.700 114.476 1.00 82.96  ? 206 CYS C N   1 
ATOM   10783 C CA  . CYS C 1 206 ? 117.129 166.705 113.768 1.00 74.51  ? 206 CYS C CA  1 
ATOM   10784 C C   . CYS C 1 206 ? 117.977 166.075 112.668 1.00 74.86  ? 206 CYS C C   1 
ATOM   10785 O O   . CYS C 1 206 ? 118.186 164.864 112.618 1.00 77.02  ? 206 CYS C O   1 
ATOM   10786 C CB  . CYS C 1 206 ? 118.024 167.474 114.749 1.00 71.17  ? 206 CYS C CB  1 
ATOM   10787 S SG  . CYS C 1 206 ? 119.386 166.459 115.370 1.00 62.37  ? 206 CYS C SG  1 
ATOM   10788 N N   . PHE C 1 207 ? 118.509 166.927 111.789 1.00 60.97  ? 207 PHE C N   1 
ATOM   10789 C CA  . PHE C 1 207 ? 119.463 166.598 110.729 1.00 47.18  ? 207 PHE C CA  1 
ATOM   10790 C C   . PHE C 1 207 ? 120.470 167.735 110.570 1.00 59.77  ? 207 PHE C C   1 
ATOM   10791 O O   . PHE C 1 207 ? 120.254 168.664 109.799 1.00 71.41  ? 207 PHE C O   1 
ATOM   10792 C CB  . PHE C 1 207 ? 118.706 166.320 109.425 1.00 55.46  ? 207 PHE C CB  1 
ATOM   10793 C CG  . PHE C 1 207 ? 119.548 166.116 108.173 1.00 60.39  ? 207 PHE C CG  1 
ATOM   10794 C CD1 . PHE C 1 207 ? 120.660 165.256 108.167 1.00 62.12  ? 207 PHE C CD1 1 
ATOM   10795 C CD2 . PHE C 1 207 ? 119.178 166.760 106.986 1.00 63.13  ? 207 PHE C CD2 1 
ATOM   10796 C CE1 . PHE C 1 207 ? 121.374 165.030 106.980 1.00 58.47  ? 207 PHE C CE1 1 
ATOM   10797 C CE2 . PHE C 1 207 ? 119.884 166.527 105.794 1.00 59.27  ? 207 PHE C CE2 1 
ATOM   10798 C CZ  . PHE C 1 207 ? 120.982 165.662 105.792 1.00 58.81  ? 207 PHE C CZ  1 
ATOM   10799 N N   . TYR C 1 208 ? 121.570 167.688 111.318 1.00 68.57  ? 208 TYR C N   1 
ATOM   10800 C CA  . TYR C 1 208 ? 122.689 168.610 111.143 1.00 66.68  ? 208 TYR C CA  1 
ATOM   10801 C C   . TYR C 1 208 ? 123.528 168.212 109.922 1.00 76.81  ? 208 TYR C C   1 
ATOM   10802 O O   . TYR C 1 208 ? 123.983 167.077 109.819 1.00 80.21  ? 208 TYR C O   1 
ATOM   10803 C CB  . TYR C 1 208 ? 123.534 168.654 112.422 1.00 63.93  ? 208 TYR C CB  1 
ATOM   10804 C CG  . TYR C 1 208 ? 124.686 169.636 112.362 1.00 67.40  ? 208 TYR C CG  1 
ATOM   10805 C CD1 . TYR C 1 208 ? 124.456 171.003 112.596 1.00 70.41  ? 208 TYR C CD1 1 
ATOM   10806 C CD2 . TYR C 1 208 ? 125.980 169.197 112.028 1.00 71.99  ? 208 TYR C CD2 1 
ATOM   10807 C CE1 . TYR C 1 208 ? 125.496 171.937 112.463 1.00 61.66  ? 208 TYR C CE1 1 
ATOM   10808 C CE2 . TYR C 1 208 ? 127.024 170.127 111.893 1.00 72.05  ? 208 TYR C CE2 1 
ATOM   10809 C CZ  . TYR C 1 208 ? 126.780 171.498 112.096 1.00 67.56  ? 208 TYR C CZ  1 
ATOM   10810 O OH  . TYR C 1 208 ? 127.777 172.392 111.904 1.00 76.90  ? 208 TYR C OH  1 
ATOM   10811 N N   . PHE C 1 209 ? 123.772 169.156 109.015 1.00 67.38  ? 209 PHE C N   1 
ATOM   10812 C CA  . PHE C 1 209 ? 124.622 169.011 107.830 1.00 60.55  ? 209 PHE C CA  1 
ATOM   10813 C C   . PHE C 1 209 ? 125.577 170.200 107.690 1.00 65.32  ? 209 PHE C C   1 
ATOM   10814 O O   . PHE C 1 209 ? 126.045 170.509 106.598 1.00 80.10  ? 209 PHE C O   1 
ATOM   10815 C CB  . PHE C 1 209 ? 123.752 168.788 106.587 1.00 64.60  ? 209 PHE C CB  1 
ATOM   10816 C CG  . PHE C 1 209 ? 122.703 169.847 106.316 1.00 61.99  ? 209 PHE C CG  1 
ATOM   10817 C CD1 . PHE C 1 209 ? 123.033 171.075 105.719 1.00 65.75  ? 209 PHE C CD1 1 
ATOM   10818 C CD2 . PHE C 1 209 ? 121.366 169.583 106.637 1.00 60.83  ? 209 PHE C CD2 1 
ATOM   10819 C CE1 . PHE C 1 209 ? 122.038 172.025 105.443 1.00 64.16  ? 209 PHE C CE1 1 
ATOM   10820 C CE2 . PHE C 1 209 ? 120.369 170.511 106.326 1.00 68.56  ? 209 PHE C CE2 1 
ATOM   10821 C CZ  . PHE C 1 209 ? 120.702 171.735 105.734 1.00 66.38  ? 209 PHE C CZ  1 
ATOM   10822 N N   . GLY C 1 210 ? 125.861 170.913 108.774 1.00 65.64  ? 210 GLY C N   1 
ATOM   10823 C CA  . GLY C 1 210 ? 126.201 172.329 108.681 1.00 63.66  ? 210 GLY C CA  1 
ATOM   10824 C C   . GLY C 1 210 ? 124.891 173.099 108.504 1.00 75.75  ? 210 GLY C C   1 
ATOM   10825 O O   . GLY C 1 210 ? 123.845 172.636 108.952 1.00 85.30  ? 210 GLY C O   1 
ATOM   10826 N N   . GLU C 1 211 ? 124.898 174.231 107.807 1.00 73.21  ? 211 GLU C N   1 
ATOM   10827 C CA  . GLU C 1 211 ? 123.652 174.938 107.445 1.00 73.08  ? 211 GLU C CA  1 
ATOM   10828 C C   . GLU C 1 211 ? 123.580 175.353 105.974 1.00 76.25  ? 211 GLU C C   1 
ATOM   10829 O O   . GLU C 1 211 ? 122.547 175.818 105.504 1.00 89.32  ? 211 GLU C O   1 
ATOM   10830 C CB  . GLU C 1 211 ? 123.466 176.167 108.338 1.00 76.05  ? 211 GLU C CB  1 
ATOM   10831 C CG  . GLU C 1 211 ? 123.275 175.809 109.817 1.00 75.41  ? 211 GLU C CG  1 
ATOM   10832 C CD  . GLU C 1 211 ? 123.209 177.036 110.732 1.00 85.16  ? 211 GLU C CD  1 
ATOM   10833 O OE1 . GLU C 1 211 ? 123.435 178.192 110.289 1.00 82.67  ? 211 GLU C OE1 1 
ATOM   10834 O OE2 . GLU C 1 211 ? 123.006 176.829 111.945 1.00 85.92  ? 211 GLU C OE2 1 
ATOM   10835 N N   . LEU C 1 212 ? 124.671 175.215 105.232 1.00 70.83  ? 212 LEU C N   1 
ATOM   10836 C CA  . LEU C 1 212 ? 124.828 175.766 103.889 1.00 74.21  ? 212 LEU C CA  1 
ATOM   10837 C C   . LEU C 1 212 ? 124.589 174.700 102.815 1.00 71.56  ? 212 LEU C C   1 
ATOM   10838 O O   . LEU C 1 212 ? 124.900 173.531 103.046 1.00 71.84  ? 212 LEU C O   1 
ATOM   10839 C CB  . LEU C 1 212 ? 126.239 176.355 103.758 1.00 79.35  ? 212 LEU C CB  1 
ATOM   10840 C CG  . LEU C 1 212 ? 126.537 177.530 104.700 1.00 74.74  ? 212 LEU C CG  1 
ATOM   10841 C CD1 . LEU C 1 212 ? 128.036 177.695 104.842 1.00 74.50  ? 212 LEU C CD1 1 
ATOM   10842 C CD2 . LEU C 1 212 ? 125.968 178.827 104.157 1.00 72.20  ? 212 LEU C CD2 1 
ATOM   10843 N N   . PRO C 1 213 ? 124.141 175.090 101.612 1.00 76.65  ? 213 PRO C N   1 
ATOM   10844 C CA  . PRO C 1 213 ? 124.091 174.236 100.430 1.00 82.91  ? 213 PRO C CA  1 
ATOM   10845 C C   . PRO C 1 213 ? 125.364 173.424 100.172 1.00 82.76  ? 213 PRO C C   1 
ATOM   10846 O O   . PRO C 1 213 ? 125.280 172.223 99.943  1.00 83.45  ? 213 PRO C O   1 
ATOM   10847 C CB  . PRO C 1 213 ? 123.798 175.204 99.283  1.00 82.79  ? 213 PRO C CB  1 
ATOM   10848 C CG  . PRO C 1 213 ? 122.899 176.236 99.938  1.00 78.44  ? 213 PRO C CG  1 
ATOM   10849 C CD  . PRO C 1 213 ? 123.529 176.370 101.315 1.00 77.28  ? 213 PRO C CD  1 
ATOM   10850 N N   . LEU C 1 214 ? 126.560 174.015 100.264 1.00 78.27  ? 214 LEU C N   1 
ATOM   10851 C CA  . LEU C 1 214 ? 127.810 173.275 100.055 1.00 79.43  ? 214 LEU C CA  1 
ATOM   10852 C C   . LEU C 1 214 ? 128.046 172.192 101.118 1.00 80.30  ? 214 LEU C C   1 
ATOM   10853 O O   . LEU C 1 214 ? 128.475 171.086 100.796 1.00 84.17  ? 214 LEU C O   1 
ATOM   10854 C CB  . LEU C 1 214 ? 128.983 174.264 99.994  1.00 77.12  ? 214 LEU C CB  1 
ATOM   10855 C CG  . LEU C 1 214 ? 130.354 173.586 99.810  1.00 79.96  ? 214 LEU C CG  1 
ATOM   10856 C CD1 . LEU C 1 214 ? 130.461 172.842 98.487  1.00 78.42  ? 214 LEU C CD1 1 
ATOM   10857 C CD2 . LEU C 1 214 ? 131.464 174.621 99.879  1.00 85.25  ? 214 LEU C CD2 1 
ATOM   10858 N N   . SER C 1 215 ? 127.740 172.482 102.380 1.00 63.13  ? 215 SER C N   1 
ATOM   10859 C CA  . SER C 1 215 ? 127.875 171.507 103.460 1.00 56.65  ? 215 SER C CA  1 
ATOM   10860 C C   . SER C 1 215 ? 126.840 170.389 103.354 1.00 65.11  ? 215 SER C C   1 
ATOM   10861 O O   . SER C 1 215 ? 127.172 169.230 103.576 1.00 69.89  ? 215 SER C O   1 
ATOM   10862 C CB  . SER C 1 215 ? 127.786 172.186 104.819 1.00 61.77  ? 215 SER C CB  1 
ATOM   10863 O OG  . SER C 1 215 ? 128.616 173.331 104.854 1.00 66.05  ? 215 SER C OG  1 
ATOM   10864 N N   . LEU C 1 216 ? 125.614 170.682 102.914 1.00 72.30  ? 216 LEU C N   1 
ATOM   10865 C CA  . LEU C 1 216 ? 124.612 169.668 102.591 1.00 70.80  ? 216 LEU C CA  1 
ATOM   10866 C C   . LEU C 1 216 ? 125.078 168.750 101.460 1.00 70.71  ? 216 LEU C C   1 
ATOM   10867 O O   . LEU C 1 216 ? 125.003 167.531 101.584 1.00 76.10  ? 216 LEU C O   1 
ATOM   10868 C CB  . LEU C 1 216 ? 123.290 170.367 102.242 1.00 68.23  ? 216 LEU C CB  1 
ATOM   10869 C CG  . LEU C 1 216 ? 122.124 169.429 101.901 1.00 62.23  ? 216 LEU C CG  1 
ATOM   10870 C CD1 . LEU C 1 216 ? 121.785 168.408 102.977 1.00 65.90  ? 216 LEU C CD1 1 
ATOM   10871 C CD2 . LEU C 1 216 ? 120.886 170.273 101.666 1.00 65.56  ? 216 LEU C CD2 1 
ATOM   10872 N N   . ALA C 1 217 ? 125.594 169.304 100.364 1.00 65.83  ? 217 ALA C N   1 
ATOM   10873 C CA  . ALA C 1 217 ? 126.091 168.529 99.234  1.00 56.94  ? 217 ALA C CA  1 
ATOM   10874 C C   . ALA C 1 217 ? 127.262 167.610 99.622  1.00 65.96  ? 217 ALA C C   1 
ATOM   10875 O O   . ALA C 1 217 ? 127.305 166.454 99.214  1.00 67.55  ? 217 ALA C O   1 
ATOM   10876 C CB  . ALA C 1 217 ? 126.469 169.506 98.122  1.00 59.69  ? 217 ALA C CB  1 
ATOM   10877 N N   . ALA C 1 218 ? 128.178 168.079 100.470 1.00 76.50  ? 218 ALA C N   1 
ATOM   10878 C CA  . ALA C 1 218 ? 129.253 167.262 101.023 1.00 66.26  ? 218 ALA C CA  1 
ATOM   10879 C C   . ALA C 1 218 ? 128.728 166.142 101.938 1.00 65.51  ? 218 ALA C C   1 
ATOM   10880 O O   . ALA C 1 218 ? 129.088 164.982 101.772 1.00 68.17  ? 218 ALA C O   1 
ATOM   10881 C CB  . ALA C 1 218 ? 130.221 168.190 101.758 1.00 58.56  ? 218 ALA C CB  1 
ATOM   10882 N N   . CYS C 1 219 ? 127.832 166.434 102.877 1.00 79.47  ? 219 CYS C N   1 
ATOM   10883 C CA  . CYS C 1 219 ? 127.346 165.437 103.834 1.00 81.32  ? 219 CYS C CA  1 
ATOM   10884 C C   . CYS C 1 219 ? 126.427 164.372 103.206 1.00 78.10  ? 219 CYS C C   1 
ATOM   10885 O O   . CYS C 1 219 ? 126.435 163.218 103.621 1.00 71.56  ? 219 CYS C O   1 
ATOM   10886 C CB  . CYS C 1 219 ? 126.683 166.174 104.996 1.00 79.96  ? 219 CYS C CB  1 
ATOM   10887 S SG  . CYS C 1 219 ? 127.922 167.246 105.771 1.00 86.37  ? 219 CYS C SG  1 
ATOM   10888 N N   . THR C 1 220 ? 125.692 164.728 102.151 1.00 82.77  ? 220 THR C N   1 
ATOM   10889 C CA  . THR C 1 220 ? 124.936 163.804 101.285 1.00 79.27  ? 220 THR C CA  1 
ATOM   10890 C C   . THR C 1 220 ? 125.801 163.126 100.205 1.00 81.98  ? 220 THR C C   1 
ATOM   10891 O O   . THR C 1 220 ? 125.279 162.344 99.412  1.00 87.06  ? 220 THR C O   1 
ATOM   10892 C CB  . THR C 1 220 ? 123.750 164.514 100.629 1.00 78.29  ? 220 THR C CB  1 
ATOM   10893 O OG1 . THR C 1 220 ? 124.191 165.618 99.893  1.00 86.61  ? 220 THR C OG1 1 
ATOM   10894 C CG2 . THR C 1 220 ? 122.723 165.050 101.610 1.00 75.83  ? 220 THR C CG2 1 
ATOM   10895 N N   . LYS C 1 221 ? 127.121 163.356 100.185 1.00 81.99  ? 221 LYS C N   1 
ATOM   10896 C CA  . LYS C 1 221 ? 128.122 162.661 99.353  1.00 77.90  ? 221 LYS C CA  1 
ATOM   10897 C C   . LYS C 1 221 ? 127.990 162.889 97.848  1.00 82.40  ? 221 LYS C C   1 
ATOM   10898 O O   . LYS C 1 221 ? 128.126 161.959 97.059  1.00 82.24  ? 221 LYS C O   1 
ATOM   10899 C CB  . LYS C 1 221 ? 128.220 161.169 99.720  1.00 75.26  ? 221 LYS C CB  1 
ATOM   10900 C CG  . LYS C 1 221 ? 128.221 160.909 101.230 1.00 85.62  ? 221 LYS C CG  1 
ATOM   10901 C CD  . LYS C 1 221 ? 128.555 159.447 101.534 1.00 88.13  ? 221 LYS C CD  1 
ATOM   10902 C CE  . LYS C 1 221 ? 128.165 159.025 102.954 1.00 85.75  ? 221 LYS C CE  1 
ATOM   10903 N NZ  . LYS C 1 221 ? 128.674 159.932 104.014 1.00 78.73  ? 221 LYS C NZ  1 
ATOM   10904 N N   . GLN C 1 222 ? 127.694 164.116 97.429  1.00 89.99  ? 222 GLN C N   1 
ATOM   10905 C CA  . GLN C 1 222 ? 127.420 164.460 96.032  1.00 88.80  ? 222 GLN C CA  1 
ATOM   10906 C C   . GLN C 1 222 ? 128.585 165.208 95.378  1.00 83.80  ? 222 GLN C C   1 
ATOM   10907 O O   . GLN C 1 222 ? 128.581 166.432 95.317  1.00 82.58  ? 222 GLN C O   1 
ATOM   10908 C CB  . GLN C 1 222 ? 126.125 165.272 95.959  1.00 87.15  ? 222 GLN C CB  1 
ATOM   10909 C CG  . GLN C 1 222 ? 124.932 164.465 96.459  1.00 83.35  ? 222 GLN C CG  1 
ATOM   10910 C CD  . GLN C 1 222 ? 123.645 165.226 96.250  1.00 84.88  ? 222 GLN C CD  1 
ATOM   10911 O OE1 . GLN C 1 222 ? 123.158 165.367 95.145  1.00 93.37  ? 222 GLN C OE1 1 
ATOM   10912 N NE2 . GLN C 1 222 ? 123.051 165.736 97.298  1.00 84.40  ? 222 GLN C NE2 1 
ATOM   10913 N N   . TRP C 1 223 ? 129.582 164.498 94.886  1.00 88.66  ? 223 TRP C N   1 
ATOM   10914 C CA  . TRP C 1 223 ? 130.713 165.273 94.336  1.00 96.10  ? 223 TRP C CA  1 
ATOM   10915 C C   . TRP C 1 223 ? 130.216 166.197 93.221  1.00 100.91 ? 223 TRP C C   1 
ATOM   10916 O O   . TRP C 1 223 ? 130.523 167.383 93.294  1.00 104.35 ? 223 TRP C O   1 
ATOM   10917 C CB  . TRP C 1 223 ? 131.828 164.336 93.876  1.00 95.88  ? 223 TRP C CB  1 
ATOM   10918 C CG  . TRP C 1 223 ? 132.696 163.852 94.992  1.00 101.37 ? 223 TRP C CG  1 
ATOM   10919 C CD1 . TRP C 1 223 ? 132.739 162.595 95.520  1.00 99.58  ? 223 TRP C CD1 1 
ATOM   10920 C CD2 . TRP C 1 223 ? 133.654 164.629 95.728  1.00 101.45 ? 223 TRP C CD2 1 
ATOM   10921 N NE1 . TRP C 1 223 ? 133.660 162.534 96.531  1.00 95.37  ? 223 TRP C NE1 1 
ATOM   10922 C CE2 . TRP C 1 223 ? 134.236 163.768 96.681  1.00 100.80 ? 223 TRP C CE2 1 
ATOM   10923 C CE3 . TRP C 1 223 ? 134.075 165.960 95.672  1.00 92.48  ? 223 TRP C CE3 1 
ATOM   10924 C CZ2 . TRP C 1 223 ? 135.218 164.199 97.567  1.00 100.23 ? 223 TRP C CZ2 1 
ATOM   10925 C CZ3 . TRP C 1 223 ? 135.040 166.383 96.554  1.00 89.91  ? 223 TRP C CZ3 1 
ATOM   10926 C CH2 . TRP C 1 223 ? 135.600 165.516 97.487  1.00 97.43  ? 223 TRP C CH2 1 
ATOM   10927 N N   . ASP C 1 224 ? 129.466 165.697 92.240  1.00 102.49 ? 224 ASP C N   1 
ATOM   10928 C CA  . ASP C 1 224 ? 129.061 166.509 91.094  1.00 98.87  ? 224 ASP C CA  1 
ATOM   10929 C C   . ASP C 1 224 ? 128.359 167.806 91.522  1.00 100.19 ? 224 ASP C C   1 
ATOM   10930 O O   . ASP C 1 224 ? 128.672 168.872 90.996  1.00 98.08  ? 224 ASP C O   1 
ATOM   10931 C CB  . ASP C 1 224 ? 128.205 165.677 90.125  1.00 101.23 ? 224 ASP C CB  1 
ATOM   10932 C CG  . ASP C 1 224 ? 127.001 164.931 90.724  1.00 102.97 ? 224 ASP C CG  1 
ATOM   10933 O OD1 . ASP C 1 224 ? 126.810 164.949 91.958  1.00 101.21 ? 224 ASP C OD1 1 
ATOM   10934 O OD2 . ASP C 1 224 ? 126.267 164.293 89.943  1.00 105.91 ? 224 ASP C OD2 1 
ATOM   10935 N N   . VAL C 1 225 ? 127.477 167.748 92.519  1.00 97.07  ? 225 VAL C N   1 
ATOM   10936 C CA  . VAL C 1 225 ? 126.860 168.940 93.119  1.00 94.41  ? 225 VAL C CA  1 
ATOM   10937 C C   . VAL C 1 225 ? 127.890 169.774 93.875  1.00 93.37  ? 225 VAL C C   1 
ATOM   10938 O O   . VAL C 1 225 ? 127.901 170.988 93.717  1.00 98.40  ? 225 VAL C O   1 
ATOM   10939 C CB  . VAL C 1 225 ? 125.673 168.578 94.027  1.00 95.55  ? 225 VAL C CB  1 
ATOM   10940 C CG1 . VAL C 1 225 ? 125.033 169.820 94.644  1.00 94.92  ? 225 VAL C CG1 1 
ATOM   10941 C CG2 . VAL C 1 225 ? 124.575 167.854 93.247  1.00 91.91  ? 225 VAL C CG2 1 
ATOM   10942 N N   . VAL C 1 226 ? 128.794 169.166 94.648  1.00 89.11  ? 226 VAL C N   1 
ATOM   10943 C CA  . VAL C 1 226 ? 129.884 169.876 95.347  1.00 91.23  ? 226 VAL C CA  1 
ATOM   10944 C C   . VAL C 1 226 ? 130.780 170.602 94.351  1.00 93.98  ? 226 VAL C C   1 
ATOM   10945 O O   . VAL C 1 226 ? 131.038 171.786 94.520  1.00 93.45  ? 226 VAL C O   1 
ATOM   10946 C CB  . VAL C 1 226 ? 130.709 168.905 96.211  1.00 90.72  ? 226 VAL C CB  1 
ATOM   10947 C CG1 . VAL C 1 226 ? 132.059 169.464 96.655  1.00 91.00  ? 226 VAL C CG1 1 
ATOM   10948 C CG2 . VAL C 1 226 ? 129.937 168.541 97.477  1.00 94.22  ? 226 VAL C CG2 1 
ATOM   10949 N N   . THR C 1 227 ? 131.195 169.927 93.278  1.00 102.83 ? 227 THR C N   1 
ATOM   10950 C CA  . THR C 1 227 ? 131.967 170.542 92.197  1.00 98.87  ? 227 THR C CA  1 
ATOM   10951 C C   . THR C 1 227 ? 131.186 171.692 91.567  1.00 96.43  ? 227 THR C C   1 
ATOM   10952 O O   . THR C 1 227 ? 131.716 172.787 91.421  1.00 95.56  ? 227 THR C O   1 
ATOM   10953 C CB  . THR C 1 227 ? 132.324 169.511 91.117  1.00 95.88  ? 227 THR C CB  1 
ATOM   10954 O OG1 . THR C 1 227 ? 133.038 168.438 91.677  1.00 95.91  ? 227 THR C OG1 1 
ATOM   10955 C CG2 . THR C 1 227 ? 133.187 170.102 90.011  1.00 93.62  ? 227 THR C CG2 1 
ATOM   10956 N N   . TYR C 1 228 ? 129.907 171.498 91.237  1.00 97.65  ? 228 TYR C N   1 
ATOM   10957 C CA  . TYR C 1 228 ? 129.113 172.565 90.643  1.00 98.45  ? 228 TYR C CA  1 
ATOM   10958 C C   . TYR C 1 228 ? 128.977 173.771 91.583  1.00 100.56 ? 228 TYR C C   1 
ATOM   10959 O O   . TYR C 1 228 ? 129.284 174.898 91.201  1.00 103.20 ? 228 TYR C O   1 
ATOM   10960 C CB  . TYR C 1 228 ? 127.754 172.023 90.204  1.00 98.98  ? 228 TYR C CB  1 
ATOM   10961 C CG  . TYR C 1 228 ? 126.961 173.088 89.489  1.00 99.66  ? 228 TYR C CG  1 
ATOM   10962 C CD1 . TYR C 1 228 ? 127.296 173.419 88.164  1.00 99.87  ? 228 TYR C CD1 1 
ATOM   10963 C CD2 . TYR C 1 228 ? 126.013 173.852 90.188  1.00 96.13  ? 228 TYR C CD2 1 
ATOM   10964 C CE1 . TYR C 1 228 ? 126.704 174.529 87.543  1.00 98.83  ? 228 TYR C CE1 1 
ATOM   10965 C CE2 . TYR C 1 228 ? 125.420 174.965 89.571  1.00 100.68 ? 228 TYR C CE2 1 
ATOM   10966 C CZ  . TYR C 1 228 ? 125.768 175.309 88.252  1.00 102.77 ? 228 TYR C CZ  1 
ATOM   10967 O OH  . TYR C 1 228 ? 125.205 176.390 87.660  1.00 102.45 ? 228 TYR C OH  1 
ATOM   10968 N N   . LEU C 1 229 ? 128.588 173.565 92.840  1.00 95.55  ? 229 LEU C N   1 
ATOM   10969 C CA  . LEU C 1 229 ? 128.471 174.657 93.802  1.00 95.14  ? 229 LEU C CA  1 
ATOM   10970 C C   . LEU C 1 229 ? 129.803 175.390 93.976  1.00 97.35  ? 229 LEU C C   1 
ATOM   10971 O O   . LEU C 1 229 ? 129.801 176.615 93.994  1.00 94.28  ? 229 LEU C O   1 
ATOM   10972 C CB  . LEU C 1 229 ? 127.948 174.121 95.143  1.00 94.99  ? 229 LEU C CB  1 
ATOM   10973 C CG  . LEU C 1 229 ? 126.477 173.681 95.134  1.00 90.89  ? 229 LEU C CG  1 
ATOM   10974 C CD1 . LEU C 1 229 ? 126.147 173.066 96.484  1.00 90.30  ? 229 LEU C CD1 1 
ATOM   10975 C CD2 . LEU C 1 229 ? 125.510 174.834 94.903  1.00 90.27  ? 229 LEU C CD2 1 
ATOM   10976 N N   . LEU C 1 230 ? 130.936 174.685 94.046  1.00 100.46 ? 230 LEU C N   1 
ATOM   10977 C CA  . LEU C 1 230 ? 132.260 175.291 94.217  1.00 95.50  ? 230 LEU C CA  1 
ATOM   10978 C C   . LEU C 1 230 ? 132.765 176.090 93.016  1.00 96.09  ? 230 LEU C C   1 
ATOM   10979 O O   . LEU C 1 230 ? 133.426 177.104 93.221  1.00 91.65  ? 230 LEU C O   1 
ATOM   10980 C CB  . LEU C 1 230 ? 133.288 174.196 94.526  1.00 91.60  ? 230 LEU C CB  1 
ATOM   10981 C CG  . LEU C 1 230 ? 133.256 173.695 95.970  1.00 90.37  ? 230 LEU C CG  1 
ATOM   10982 C CD1 . LEU C 1 230 ? 134.238 172.542 96.142  1.00 93.64  ? 230 LEU C CD1 1 
ATOM   10983 C CD2 . LEU C 1 230 ? 133.666 174.777 96.952  1.00 89.07  ? 230 LEU C CD2 1 
ATOM   10984 N N   . GLU C 1 231 ? 132.509 175.652 91.779  1.00 109.66 ? 231 GLU C N   1 
ATOM   10985 C CA  . GLU C 1 231 ? 133.152 176.237 90.591  1.00 107.89 ? 231 GLU C CA  1 
ATOM   10986 C C   . GLU C 1 231 ? 132.215 176.575 89.409  1.00 108.07 ? 231 GLU C C   1 
ATOM   10987 O O   . GLU C 1 231 ? 132.679 176.783 88.291  1.00 112.19 ? 231 GLU C O   1 
ATOM   10988 C CB  . GLU C 1 231 ? 134.436 175.458 90.228  1.00 108.80 ? 231 GLU C CB  1 
ATOM   10989 C CG  . GLU C 1 231 ? 134.256 173.957 89.974  1.00 108.57 ? 231 GLU C CG  1 
ATOM   10990 C CD  . GLU C 1 231 ? 135.537 173.302 89.436  1.00 110.65 ? 231 GLU C CD  1 
ATOM   10991 O OE1 . GLU C 1 231 ? 136.581 173.309 90.130  1.00 110.74 ? 231 GLU C OE1 1 
ATOM   10992 O OE2 . GLU C 1 231 ? 135.501 172.753 88.311  1.00 108.37 ? 231 GLU C OE2 1 
ATOM   10993 N N   . ASN C 1 232 ? 130.905 176.718 89.636  1.00 108.03 ? 232 ASN C N   1 
ATOM   10994 C CA  . ASN C 1 232 ? 130.008 177.395 88.690  1.00 110.37 ? 232 ASN C CA  1 
ATOM   10995 C C   . ASN C 1 232 ? 130.354 178.898 88.536  1.00 113.30 ? 232 ASN C C   1 
ATOM   10996 O O   . ASN C 1 232 ? 130.866 179.510 89.478  1.00 113.21 ? 232 ASN C O   1 
ATOM   10997 C CB  . ASN C 1 232 ? 128.537 177.211 89.110  1.00 111.34 ? 232 ASN C CB  1 
ATOM   10998 C CG  . ASN C 1 232 ? 128.130 178.101 90.271  1.00 108.53 ? 232 ASN C CG  1 
ATOM   10999 O OD1 . ASN C 1 232 ? 127.707 179.227 90.074  1.00 107.48 ? 232 ASN C OD1 1 
ATOM   11000 N ND2 . ASN C 1 232 ? 128.254 177.645 91.488  1.00 107.06 ? 232 ASN C ND2 1 
ATOM   11001 N N   . PRO C 1 233 ? 130.057 179.532 87.385  1.00 117.97 ? 233 PRO C N   1 
ATOM   11002 C CA  . PRO C 1 233 ? 130.378 180.941 87.146  1.00 117.40 ? 233 PRO C CA  1 
ATOM   11003 C C   . PRO C 1 233 ? 129.365 181.942 87.733  1.00 117.22 ? 233 PRO C C   1 
ATOM   11004 O O   . PRO C 1 233 ? 129.637 183.142 87.734  1.00 115.05 ? 233 PRO C O   1 
ATOM   11005 C CB  . PRO C 1 233 ? 130.437 181.055 85.622  1.00 114.29 ? 233 PRO C CB  1 
ATOM   11006 C CG  . PRO C 1 233 ? 129.394 180.045 85.159  1.00 114.59 ? 233 PRO C CG  1 
ATOM   11007 C CD  . PRO C 1 233 ? 129.560 178.911 86.167  1.00 114.98 ? 233 PRO C CD  1 
ATOM   11008 N N   . HIS C 1 234 ? 128.192 181.494 88.189  1.00 118.20 ? 234 HIS C N   1 
ATOM   11009 C CA  . HIS C 1 234 ? 127.089 182.371 88.616  1.00 118.76 ? 234 HIS C CA  1 
ATOM   11010 C C   . HIS C 1 234 ? 127.267 182.873 90.050  1.00 121.25 ? 234 HIS C C   1 
ATOM   11011 O O   . HIS C 1 234 ? 127.245 184.075 90.300  1.00 120.06 ? 234 HIS C O   1 
ATOM   11012 C CB  . HIS C 1 234 ? 125.749 181.638 88.450  1.00 117.31 ? 234 HIS C CB  1 
ATOM   11013 C CG  . HIS C 1 234 ? 125.557 181.058 87.074  1.00 116.42 ? 234 HIS C CG  1 
ATOM   11014 N ND1 . HIS C 1 234 ? 125.365 181.795 85.905  1.00 117.99 ? 234 HIS C ND1 1 
ATOM   11015 C CD2 . HIS C 1 234 ? 125.605 179.733 86.760  1.00 116.94 ? 234 HIS C CD2 1 
ATOM   11016 C CE1 . HIS C 1 234 ? 125.303 180.893 84.914  1.00 120.01 ? 234 HIS C CE1 1 
ATOM   11017 N NE2 . HIS C 1 234 ? 125.449 179.650 85.396  1.00 119.63 ? 234 HIS C NE2 1 
ATOM   11018 N N   . GLN C 1 235 ? 127.564 181.916 90.938  1.00 119.94 ? 235 GLN C N   1 
ATOM   11019 C CA  . GLN C 1 235 ? 127.834 182.225 92.362  1.00 116.37 ? 235 GLN C CA  1 
ATOM   11020 C C   . GLN C 1 235 ? 128.605 181.028 92.929  1.00 119.53 ? 235 GLN C C   1 
ATOM   11021 O O   . GLN C 1 235 ? 127.948 180.030 93.264  1.00 117.29 ? 235 GLN C O   1 
ATOM   11022 C CB  . GLN C 1 235 ? 126.530 182.443 93.124  1.00 115.66 ? 235 GLN C CB  1 
ATOM   11023 C CG  . GLN C 1 235 ? 126.713 182.467 94.634  1.00 120.55 ? 235 GLN C CG  1 
ATOM   11024 C CD  . GLN C 1 235 ? 125.517 183.034 95.357  1.00 120.68 ? 235 GLN C CD  1 
ATOM   11025 O OE1 . GLN C 1 235 ? 124.472 183.288 94.764  1.00 116.82 ? 235 GLN C OE1 1 
ATOM   11026 N NE2 . GLN C 1 235 ? 125.667 183.238 96.655  1.00 118.62 ? 235 GLN C NE2 1 
ATOM   11027 N N   . PRO C 1 236 ? 129.959 181.044 92.984  1.00 117.84 ? 236 PRO C N   1 
ATOM   11028 C CA  . PRO C 1 236 ? 130.737 179.964 93.571  1.00 115.34 ? 236 PRO C CA  1 
ATOM   11029 C C   . PRO C 1 236 ? 130.568 179.949 95.096  1.00 111.69 ? 236 PRO C C   1 
ATOM   11030 O O   . PRO C 1 236 ? 130.629 180.988 95.754  1.00 109.82 ? 236 PRO C O   1 
ATOM   11031 C CB  . PRO C 1 236 ? 132.176 180.226 93.130  1.00 110.66 ? 236 PRO C CB  1 
ATOM   11032 C CG  . PRO C 1 236 ? 132.233 181.735 92.932  1.00 109.75 ? 236 PRO C CG  1 
ATOM   11033 C CD  . PRO C 1 236 ? 130.825 182.092 92.473  1.00 111.32 ? 236 PRO C CD  1 
ATOM   11034 N N   . ALA C 1 237 ? 130.359 178.765 95.662  1.00 104.22 ? 237 ALA C N   1 
ATOM   11035 C CA  . ALA C 1 237 ? 130.333 178.540 97.093  1.00 102.71 ? 237 ALA C CA  1 
ATOM   11036 C C   . ALA C 1 237 ? 131.710 178.835 97.694  1.00 107.33 ? 237 ALA C C   1 
ATOM   11037 O O   . ALA C 1 237 ? 132.718 178.272 97.271  1.00 108.63 ? 237 ALA C O   1 
ATOM   11038 C CB  . ALA C 1 237 ? 129.912 177.096 97.360  1.00 99.93  ? 237 ALA C CB  1 
ATOM   11039 N N   . SER C 1 238 ? 131.788 179.707 98.692  1.00 97.91  ? 238 SER C N   1 
ATOM   11040 C CA  . SER C 1 238 ? 133.039 179.944 99.401  1.00 94.82  ? 238 SER C CA  1 
ATOM   11041 C C   . SER C 1 238 ? 133.333 178.783 100.349 1.00 96.55  ? 238 SER C C   1 
ATOM   11042 O O   . SER C 1 238 ? 132.536 178.488 101.235 1.00 96.76  ? 238 SER C O   1 
ATOM   11043 C CB  . SER C 1 238 ? 132.969 181.274 100.142 1.00 95.03  ? 238 SER C CB  1 
ATOM   11044 O OG  . SER C 1 238 ? 134.192 181.519 100.797 1.00 99.13  ? 238 SER C OG  1 
ATOM   11045 N N   . LEU C 1 239 ? 134.498 178.148 100.215 1.00 93.87  ? 239 LEU C N   1 
ATOM   11046 C CA  . LEU C 1 239 ? 134.986 177.173 101.197 1.00 91.60  ? 239 LEU C CA  1 
ATOM   11047 C C   . LEU C 1 239 ? 135.255 177.809 102.563 1.00 90.88  ? 239 LEU C C   1 
ATOM   11048 O O   . LEU C 1 239 ? 135.339 177.094 103.549 1.00 90.25  ? 239 LEU C O   1 
ATOM   11049 C CB  . LEU C 1 239 ? 136.258 176.492 100.667 1.00 92.24  ? 239 LEU C CB  1 
ATOM   11050 C CG  . LEU C 1 239 ? 135.947 175.431 99.608  1.00 91.60  ? 239 LEU C CG  1 
ATOM   11051 C CD1 . LEU C 1 239 ? 137.162 175.147 98.744  1.00 94.30  ? 239 LEU C CD1 1 
ATOM   11052 C CD2 . LEU C 1 239 ? 135.519 174.117 100.251 1.00 87.45  ? 239 LEU C CD2 1 
ATOM   11053 N N   . GLU C 1 240 ? 135.372 179.133 102.649 1.00 99.05  ? 240 GLU C N   1 
ATOM   11054 C CA  . GLU C 1 240 ? 135.518 179.864 103.908 1.00 101.82 ? 240 GLU C CA  1 
ATOM   11055 C C   . GLU C 1 240 ? 134.181 180.133 104.622 1.00 104.53 ? 240 GLU C C   1 
ATOM   11056 O O   . GLU C 1 240 ? 134.186 180.652 105.737 1.00 105.99 ? 240 GLU C O   1 
ATOM   11057 C CB  . GLU C 1 240 ? 136.213 181.210 103.656 1.00 101.81 ? 240 GLU C CB  1 
ATOM   11058 C CG  . GLU C 1 240 ? 137.507 181.126 102.848 1.00 103.97 ? 240 GLU C CG  1 
ATOM   11059 C CD  . GLU C 1 240 ? 138.144 182.516 102.709 1.00 106.97 ? 240 GLU C CD  1 
ATOM   11060 O OE1 . GLU C 1 240 ? 138.426 183.163 103.741 1.00 103.77 ? 240 GLU C OE1 1 
ATOM   11061 O OE2 . GLU C 1 240 ? 138.347 182.976 101.565 1.00 105.08 ? 240 GLU C OE2 1 
ATOM   11062 N N   . ALA C 1 241 ? 133.031 179.853 104.000 1.00 92.00  ? 241 ALA C N   1 
ATOM   11063 C CA  . ALA C 1 241 ? 131.714 180.160 104.560 1.00 88.39  ? 241 ALA C CA  1 
ATOM   11064 C C   . ALA C 1 241 ? 131.370 179.291 105.776 1.00 88.54  ? 241 ALA C C   1 
ATOM   11065 O O   . ALA C 1 241 ? 131.704 178.108 105.829 1.00 91.13  ? 241 ALA C O   1 
ATOM   11066 C CB  . ALA C 1 241 ? 130.654 180.022 103.471 1.00 87.38  ? 241 ALA C CB  1 
ATOM   11067 N N   . THR C 1 242 ? 130.662 179.873 106.744 1.00 82.95  ? 242 THR C N   1 
ATOM   11068 C CA  . THR C 1 242 ? 130.389 179.265 108.052 1.00 85.09  ? 242 THR C CA  1 
ATOM   11069 C C   . THR C 1 242 ? 128.911 179.266 108.424 1.00 91.34  ? 242 THR C C   1 
ATOM   11070 O O   . THR C 1 242 ? 128.189 180.218 108.141 1.00 89.94  ? 242 THR C O   1 
ATOM   11071 C CB  . THR C 1 242 ? 131.163 179.983 109.162 1.00 85.26  ? 242 THR C CB  1 
ATOM   11072 O OG1 . THR C 1 242 ? 130.824 181.350 109.221 1.00 90.68  ? 242 THR C OG1 1 
ATOM   11073 C CG2 . THR C 1 242 ? 132.674 179.894 109.011 1.00 86.22  ? 242 THR C CG2 1 
ATOM   11074 N N   . ASP C 1 243 ? 128.467 178.228 109.128 1.00 81.71  ? 243 ASP C N   1 
ATOM   11075 C CA  . ASP C 1 243 ? 127.138 178.172 109.737 1.00 73.84  ? 243 ASP C CA  1 
ATOM   11076 C C   . ASP C 1 243 ? 126.998 179.031 111.022 1.00 79.08  ? 243 ASP C C   1 
ATOM   11077 O O   . ASP C 1 243 ? 127.909 179.773 111.391 1.00 80.19  ? 243 ASP C O   1 
ATOM   11078 C CB  . ASP C 1 243 ? 126.767 176.699 109.937 1.00 78.49  ? 243 ASP C CB  1 
ATOM   11079 C CG  . ASP C 1 243 ? 127.323 175.972 111.159 1.00 82.11  ? 243 ASP C CG  1 
ATOM   11080 O OD1 . ASP C 1 243 ? 128.024 176.604 111.971 1.00 88.38  ? 243 ASP C OD1 1 
ATOM   11081 O OD2 . ASP C 1 243 ? 127.028 174.765 111.293 1.00 88.00  ? 243 ASP C OD2 1 
ATOM   11082 N N   . SER C 1 244 ? 125.861 178.950 111.723 1.00 90.34  ? 244 SER C N   1 
ATOM   11083 C CA  . SER C 1 244 ? 125.602 179.689 112.973 1.00 90.42  ? 244 SER C CA  1 
ATOM   11084 C C   . SER C 1 244 ? 126.517 179.331 114.148 1.00 87.38  ? 244 SER C C   1 
ATOM   11085 O O   . SER C 1 244 ? 126.650 180.138 115.067 1.00 85.83  ? 244 SER C O   1 
ATOM   11086 C CB  . SER C 1 244 ? 124.157 179.472 113.433 1.00 88.89  ? 244 SER C CB  1 
ATOM   11087 O OG  . SER C 1 244 ? 123.938 178.157 113.889 1.00 90.21  ? 244 SER C OG  1 
ATOM   11088 N N   . LEU C 1 245 ? 127.159 178.162 114.145 1.00 79.85  ? 245 LEU C N   1 
ATOM   11089 C CA  . LEU C 1 245 ? 128.176 177.753 115.121 1.00 80.26  ? 245 LEU C CA  1 
ATOM   11090 C C   . LEU C 1 245 ? 129.589 178.163 114.682 1.00 83.37  ? 245 LEU C C   1 
ATOM   11091 O O   . LEU C 1 245 ? 130.562 177.885 115.380 1.00 85.23  ? 245 LEU C O   1 
ATOM   11092 C CB  . LEU C 1 245 ? 128.123 176.230 115.342 1.00 83.81  ? 245 LEU C CB  1 
ATOM   11093 C CG  . LEU C 1 245 ? 126.757 175.651 115.727 1.00 86.52  ? 245 LEU C CG  1 
ATOM   11094 C CD1 . LEU C 1 245 ? 126.886 174.140 115.903 1.00 82.97  ? 245 LEU C CD1 1 
ATOM   11095 C CD2 . LEU C 1 245 ? 126.232 176.251 117.029 1.00 84.76  ? 245 LEU C CD2 1 
ATOM   11096 N N   . GLY C 1 246 ? 129.728 178.781 113.510 1.00 81.20  ? 246 GLY C N   1 
ATOM   11097 C CA  . GLY C 1 246 ? 131.004 179.086 112.881 1.00 71.44  ? 246 GLY C CA  1 
ATOM   11098 C C   . GLY C 1 246 ? 131.631 177.893 112.159 1.00 73.50  ? 246 GLY C C   1 
ATOM   11099 O O   . GLY C 1 246 ? 132.762 177.997 111.701 1.00 83.55  ? 246 GLY C O   1 
ATOM   11100 N N   . ASN C 1 247 ? 130.946 176.754 112.046 1.00 71.61  ? 247 ASN C N   1 
ATOM   11101 C CA  . ASN C 1 247 ? 131.479 175.569 111.390 1.00 67.02  ? 247 ASN C CA  1 
ATOM   11102 C C   . ASN C 1 247 ? 131.573 175.785 109.876 1.00 73.09  ? 247 ASN C C   1 
ATOM   11103 O O   . ASN C 1 247 ? 130.594 176.122 109.219 1.00 74.88  ? 247 ASN C O   1 
ATOM   11104 C CB  . ASN C 1 247 ? 130.623 174.342 111.744 1.00 63.32  ? 247 ASN C CB  1 
ATOM   11105 C CG  . ASN C 1 247 ? 130.889 173.785 113.125 1.00 69.90  ? 247 ASN C CG  1 
ATOM   11106 O OD1 . ASN C 1 247 ? 131.826 174.144 113.806 1.00 78.84  ? 247 ASN C OD1 1 
ATOM   11107 N ND2 . ASN C 1 247 ? 130.102 172.851 113.579 1.00 75.50  ? 247 ASN C ND2 1 
ATOM   11108 N N   . THR C 1 248 ? 132.758 175.554 109.321 1.00 81.91  ? 248 THR C N   1 
ATOM   11109 C CA  . THR C 1 248 ? 133.022 175.423 107.881 1.00 78.55  ? 248 THR C CA  1 
ATOM   11110 C C   . THR C 1 248 ? 132.613 174.019 107.412 1.00 74.39  ? 248 THR C C   1 
ATOM   11111 O O   . THR C 1 248 ? 132.354 173.149 108.241 1.00 75.25  ? 248 THR C O   1 
ATOM   11112 C CB  . THR C 1 248 ? 134.519 175.715 107.642 1.00 80.79  ? 248 THR C CB  1 
ATOM   11113 O OG1 . THR C 1 248 ? 134.822 177.004 108.110 1.00 75.16  ? 248 THR C OG1 1 
ATOM   11114 C CG2 . THR C 1 248 ? 134.964 175.693 106.194 1.00 82.91  ? 248 THR C CG2 1 
ATOM   11115 N N   . VAL C 1 249 ? 132.581 173.722 106.114 1.00 62.90  ? 249 VAL C N   1 
ATOM   11116 C CA  . VAL C 1 249 ? 132.248 172.373 105.604 1.00 65.71  ? 249 VAL C CA  1 
ATOM   11117 C C   . VAL C 1 249 ? 133.129 171.256 106.187 1.00 72.87  ? 249 VAL C C   1 
ATOM   11118 O O   . VAL C 1 249 ? 132.663 170.138 106.370 1.00 81.07  ? 249 VAL C O   1 
ATOM   11119 C CB  . VAL C 1 249 ? 132.224 172.350 104.063 1.00 64.51  ? 249 VAL C CB  1 
ATOM   11120 C CG1 . VAL C 1 249 ? 133.555 172.694 103.404 1.00 71.51  ? 249 VAL C CG1 1 
ATOM   11121 C CG2 . VAL C 1 249 ? 131.787 170.987 103.538 1.00 67.79  ? 249 VAL C CG2 1 
ATOM   11122 N N   . LEU C 1 250 ? 134.374 171.560 106.566 1.00 71.29  ? 250 LEU C N   1 
ATOM   11123 C CA  . LEU C 1 250 ? 135.300 170.613 107.187 1.00 63.40  ? 250 LEU C CA  1 
ATOM   11124 C C   . LEU C 1 250 ? 134.959 170.333 108.659 1.00 66.69  ? 250 LEU C C   1 
ATOM   11125 O O   . LEU C 1 250 ? 135.076 169.196 109.099 1.00 70.71  ? 250 LEU C O   1 
ATOM   11126 C CB  . LEU C 1 250 ? 136.744 171.114 107.011 1.00 70.30  ? 250 LEU C CB  1 
ATOM   11127 C CG  . LEU C 1 250 ? 137.234 171.284 105.561 1.00 64.05  ? 250 LEU C CG  1 
ATOM   11128 C CD1 . LEU C 1 250 ? 138.690 171.722 105.568 1.00 68.54  ? 250 LEU C CD1 1 
ATOM   11129 C CD2 . LEU C 1 250 ? 137.136 170.000 104.746 1.00 65.55  ? 250 LEU C CD2 1 
ATOM   11130 N N   . HIS C 1 251 ? 134.459 171.320 109.394 1.00 65.41  ? 251 HIS C N   1 
ATOM   11131 C CA  . HIS C 1 251 ? 133.864 171.080 110.697 1.00 62.50  ? 251 HIS C CA  1 
ATOM   11132 C C   . HIS C 1 251 ? 132.558 170.299 110.578 1.00 71.34  ? 251 HIS C C   1 
ATOM   11133 O O   . HIS C 1 251 ? 132.305 169.418 111.388 1.00 80.41  ? 251 HIS C O   1 
ATOM   11134 C CB  . HIS C 1 251 ? 133.587 172.403 111.394 1.00 71.17  ? 251 HIS C CB  1 
ATOM   11135 C CG  . HIS C 1 251 ? 134.746 173.339 111.549 1.00 67.08  ? 251 HIS C CG  1 
ATOM   11136 N ND1 . HIS C 1 251 ? 135.139 174.286 110.611 1.00 61.43  ? 251 HIS C ND1 1 
ATOM   11137 C CD2 . HIS C 1 251 ? 135.475 173.510 112.679 1.00 63.84  ? 251 HIS C CD2 1 
ATOM   11138 C CE1 . HIS C 1 251 ? 136.099 175.009 111.191 1.00 63.24  ? 251 HIS C CE1 1 
ATOM   11139 N NE2 . HIS C 1 251 ? 136.311 174.566 112.433 1.00 68.48  ? 251 HIS C NE2 1 
ATOM   11140 N N   . ALA C 1 252 ? 131.738 170.581 109.565 1.00 63.39  ? 252 ALA C N   1 
ATOM   11141 C CA  . ALA C 1 252 ? 130.501 169.849 109.321 1.00 56.92  ? 252 ALA C CA  1 
ATOM   11142 C C   . ALA C 1 252 ? 130.764 168.368 109.037 1.00 61.20  ? 252 ALA C C   1 
ATOM   11143 O O   . ALA C 1 252 ? 130.169 167.516 109.686 1.00 74.16  ? 252 ALA C O   1 
ATOM   11144 C CB  . ALA C 1 252 ? 129.720 170.525 108.196 1.00 57.80  ? 252 ALA C CB  1 
ATOM   11145 N N   . LEU C 1 253 ? 131.718 168.031 108.171 1.00 66.34  ? 253 LEU C N   1 
ATOM   11146 C CA  . LEU C 1 253 ? 132.133 166.646 107.929 1.00 59.45  ? 253 LEU C CA  1 
ATOM   11147 C C   . LEU C 1 253 ? 132.693 165.956 109.175 1.00 54.46  ? 253 LEU C C   1 
ATOM   11148 O O   . LEU C 1 253 ? 132.394 164.794 109.413 1.00 63.43  ? 253 LEU C O   1 
ATOM   11149 C CB  . LEU C 1 253 ? 133.169 166.622 106.804 1.00 60.41  ? 253 LEU C CB  1 
ATOM   11150 C CG  . LEU C 1 253 ? 132.551 166.788 105.416 1.00 60.40  ? 253 LEU C CG  1 
ATOM   11151 C CD1 . LEU C 1 253 ? 133.667 166.997 104.413 1.00 65.56  ? 253 LEU C CD1 1 
ATOM   11152 C CD2 . LEU C 1 253 ? 131.777 165.550 104.970 1.00 63.82  ? 253 LEU C CD2 1 
ATOM   11153 N N   . VAL C 1 254 ? 133.438 166.657 110.027 1.00 63.22  ? 254 VAL C N   1 
ATOM   11154 C CA  . VAL C 1 254 ? 133.882 166.111 111.320 1.00 62.49  ? 254 VAL C CA  1 
ATOM   11155 C C   . VAL C 1 254 ? 132.704 165.873 112.267 1.00 63.46  ? 254 VAL C C   1 
ATOM   11156 O O   . VAL C 1 254 ? 132.656 164.848 112.945 1.00 73.90  ? 254 VAL C O   1 
ATOM   11157 C CB  . VAL C 1 254 ? 134.946 167.029 111.933 1.00 67.15  ? 254 VAL C CB  1 
ATOM   11158 C CG1 . VAL C 1 254 ? 135.234 166.690 113.387 1.00 73.00  ? 254 VAL C CG1 1 
ATOM   11159 C CG2 . VAL C 1 254 ? 136.263 166.899 111.168 1.00 64.15  ? 254 VAL C CG2 1 
ATOM   11160 N N   . MET C 1 255 ? 131.704 166.753 112.301 1.00 67.69  ? 255 MET C N   1 
ATOM   11161 C CA  . MET C 1 255 ? 130.495 166.557 113.112 1.00 65.98  ? 255 MET C CA  1 
ATOM   11162 C C   . MET C 1 255 ? 129.693 165.324 112.684 1.00 69.56  ? 255 MET C C   1 
ATOM   11163 O O   . MET C 1 255 ? 129.117 164.643 113.526 1.00 73.49  ? 255 MET C O   1 
ATOM   11164 C CB  . MET C 1 255 ? 129.597 167.796 113.037 1.00 65.07  ? 255 MET C CB  1 
ATOM   11165 C CG  . MET C 1 255 ? 130.102 168.938 113.906 1.00 61.67  ? 255 MET C CG  1 
ATOM   11166 S SD  . MET C 1 255 ? 129.981 168.587 115.677 1.00 79.34  ? 255 MET C SD  1 
ATOM   11167 C CE  . MET C 1 255 ? 129.904 170.279 116.308 1.00 69.47  ? 255 MET C CE  1 
ATOM   11168 N N   . ILE C 1 256 ? 129.705 165.005 111.395 1.00 77.73  ? 256 ILE C N   1 
ATOM   11169 C CA  . ILE C 1 256 ? 128.901 163.956 110.747 1.00 72.38  ? 256 ILE C CA  1 
ATOM   11170 C C   . ILE C 1 256 ? 129.623 162.614 110.614 1.00 75.84  ? 256 ILE C C   1 
ATOM   11171 O O   . ILE C 1 256 ? 128.985 161.591 110.371 1.00 80.29  ? 256 ILE C O   1 
ATOM   11172 C CB  . ILE C 1 256 ? 128.415 164.559 109.421 1.00 72.64  ? 256 ILE C CB  1 
ATOM   11173 C CG1 . ILE C 1 256 ? 127.265 165.498 109.825 1.00 75.38  ? 256 ILE C CG1 1 
ATOM   11174 C CG2 . ILE C 1 256 ? 127.986 163.581 108.333 1.00 69.78  ? 256 ILE C CG2 1 
ATOM   11175 C CD1 . ILE C 1 256 ? 127.062 166.639 108.859 1.00 75.53  ? 256 ILE C CD1 1 
ATOM   11176 N N   . ALA C 1 257 ? 130.932 162.579 110.848 1.00 77.53  ? 257 ALA C N   1 
ATOM   11177 C CA  . ALA C 1 257 ? 131.679 161.337 110.935 1.00 74.31  ? 257 ALA C CA  1 
ATOM   11178 C C   . ALA C 1 257 ? 131.134 160.433 112.051 1.00 78.91  ? 257 ALA C C   1 
ATOM   11179 O O   . ALA C 1 257 ? 130.986 160.868 113.189 1.00 82.87  ? 257 ALA C O   1 
ATOM   11180 C CB  . ALA C 1 257 ? 133.153 161.664 111.156 1.00 75.42  ? 257 ALA C CB  1 
ATOM   11181 N N   . ASP C 1 258 ? 130.922 159.161 111.750 1.00 97.99  ? 258 ASP C N   1 
ATOM   11182 C CA  . ASP C 1 258 ? 130.714 158.070 112.699 1.00 99.80  ? 258 ASP C CA  1 
ATOM   11183 C C   . ASP C 1 258 ? 131.877 157.089 112.542 1.00 105.01 ? 258 ASP C C   1 
ATOM   11184 O O   . ASP C 1 258 ? 132.448 156.946 111.461 1.00 105.93 ? 258 ASP C O   1 
ATOM   11185 C CB  . ASP C 1 258 ? 129.379 157.348 112.458 1.00 101.45 ? 258 ASP C CB  1 
ATOM   11186 C CG  . ASP C 1 258 ? 128.143 158.108 112.951 1.00 107.18 ? 258 ASP C CG  1 
ATOM   11187 O OD1 . ASP C 1 258 ? 128.265 158.963 113.851 1.00 108.56 ? 258 ASP C OD1 1 
ATOM   11188 O OD2 . ASP C 1 258 ? 127.028 157.777 112.496 1.00 104.13 ? 258 ASP C OD2 1 
ATOM   11189 N N   . ASN C 1 259 ? 132.260 156.410 113.614 1.00 101.43 ? 259 ASN C N   1 
ATOM   11190 C CA  . ASN C 1 259 ? 133.478 155.600 113.627 1.00 103.46 ? 259 ASN C CA  1 
ATOM   11191 C C   . ASN C 1 259 ? 133.322 154.229 112.929 1.00 104.57 ? 259 ASN C C   1 
ATOM   11192 O O   . ASN C 1 259 ? 134.173 153.355 113.075 1.00 104.00 ? 259 ASN C O   1 
ATOM   11193 C CB  . ASN C 1 259 ? 134.001 155.524 115.069 1.00 101.81 ? 259 ASN C CB  1 
ATOM   11194 C CG  . ASN C 1 259 ? 134.176 156.902 115.683 1.00 98.20  ? 259 ASN C CG  1 
ATOM   11195 O OD1 . ASN C 1 259 ? 134.943 157.725 115.214 1.00 94.50  ? 259 ASN C OD1 1 
ATOM   11196 N ND2 . ASN C 1 259 ? 133.448 157.211 116.731 1.00 99.37  ? 259 ASN C ND2 1 
ATOM   11197 N N   . SER C 1 260 ? 132.240 154.015 112.173 1.00 106.87 ? 260 SER C N   1 
ATOM   11198 C CA  . SER C 1 260 ? 132.030 152.826 111.344 1.00 106.29 ? 260 SER C CA  1 
ATOM   11199 C C   . SER C 1 260 ? 132.869 152.893 110.060 1.00 105.46 ? 260 SER C C   1 
ATOM   11200 O O   . SER C 1 260 ? 133.166 153.984 109.569 1.00 106.21 ? 260 SER C O   1 
ATOM   11201 C CB  . SER C 1 260 ? 130.539 152.671 111.026 1.00 106.59 ? 260 SER C CB  1 
ATOM   11202 O OG  . SER C 1 260 ? 130.067 153.753 110.250 1.00 105.89 ? 260 SER C OG  1 
ATOM   11203 N N   . PRO C 1 261 ? 133.272 151.755 109.468 1.00 109.40 ? 261 PRO C N   1 
ATOM   11204 C CA  . PRO C 1 261 ? 134.181 151.759 108.321 1.00 111.20 ? 261 PRO C CA  1 
ATOM   11205 C C   . PRO C 1 261 ? 133.542 152.330 107.049 1.00 108.89 ? 261 PRO C C   1 
ATOM   11206 O O   . PRO C 1 261 ? 134.237 152.918 106.229 1.00 102.36 ? 261 PRO C O   1 
ATOM   11207 C CB  . PRO C 1 261 ? 134.613 150.303 108.145 1.00 109.67 ? 261 PRO C CB  1 
ATOM   11208 C CG  . PRO C 1 261 ? 133.473 149.501 108.764 1.00 106.65 ? 261 PRO C CG  1 
ATOM   11209 C CD  . PRO C 1 261 ? 133.006 150.397 109.905 1.00 107.01 ? 261 PRO C CD  1 
ATOM   11210 N N   . GLU C 1 262 ? 132.226 152.203 106.886 1.00 106.55 ? 262 GLU C N   1 
ATOM   11211 C CA  . GLU C 1 262 ? 131.502 152.711 105.714 1.00 108.72 ? 262 GLU C CA  1 
ATOM   11212 C C   . GLU C 1 262 ? 131.328 154.233 105.748 1.00 111.14 ? 262 GLU C C   1 
ATOM   11213 O O   . GLU C 1 262 ? 131.606 154.905 104.756 1.00 110.11 ? 262 GLU C O   1 
ATOM   11214 C CB  . GLU C 1 262 ? 130.135 152.016 105.603 1.00 104.30 ? 262 GLU C CB  1 
ATOM   11215 N N   . ASN C 1 263 ? 130.919 154.805 106.882 1.00 98.28  ? 263 ASN C N   1 
ATOM   11216 C CA  . ASN C 1 263 ? 130.815 156.257 107.032 1.00 94.80  ? 263 ASN C CA  1 
ATOM   11217 C C   . ASN C 1 263 ? 132.202 156.900 106.984 1.00 100.69 ? 263 ASN C C   1 
ATOM   11218 O O   . ASN C 1 263 ? 132.452 157.762 106.145 1.00 101.17 ? 263 ASN C O   1 
ATOM   11219 C CB  . ASN C 1 263 ? 130.061 156.583 108.330 1.00 97.16  ? 263 ASN C CB  1 
ATOM   11220 C CG  . ASN C 1 263 ? 130.018 158.068 108.641 1.00 97.70  ? 263 ASN C CG  1 
ATOM   11221 O OD1 . ASN C 1 263 ? 131.025 158.671 108.956 1.00 100.84 ? 263 ASN C OD1 1 
ATOM   11222 N ND2 . ASN C 1 263 ? 128.880 158.701 108.604 1.00 95.96  ? 263 ASN C ND2 1 
ATOM   11223 N N   . SER C 1 264 ? 133.124 156.467 107.848 1.00 97.85  ? 264 SER C N   1 
ATOM   11224 C CA  . SER C 1 264 ? 134.414 157.141 107.997 1.00 90.45  ? 264 SER C CA  1 
ATOM   11225 C C   . SER C 1 264 ? 135.236 157.125 106.716 1.00 90.04  ? 264 SER C C   1 
ATOM   11226 O O   . SER C 1 264 ? 135.760 158.171 106.351 1.00 95.19  ? 264 SER C O   1 
ATOM   11227 C CB  . SER C 1 264 ? 135.217 156.561 109.156 1.00 92.08  ? 264 SER C CB  1 
ATOM   11228 O OG  . SER C 1 264 ? 135.467 155.188 108.971 1.00 96.92  ? 264 SER C OG  1 
ATOM   11229 N N   . ALA C 1 265 ? 135.298 156.023 105.964 1.00 96.79  ? 265 ALA C N   1 
ATOM   11230 C CA  . ALA C 1 265 ? 136.028 155.992 104.696 1.00 96.00  ? 265 ALA C CA  1 
ATOM   11231 C C   . ALA C 1 265 ? 135.470 156.989 103.675 1.00 95.18  ? 265 ALA C C   1 
ATOM   11232 O O   . ALA C 1 265 ? 136.234 157.668 102.994 1.00 91.71  ? 265 ALA C O   1 
ATOM   11233 C CB  . ALA C 1 265 ? 135.998 154.573 104.139 1.00 95.92  ? 265 ALA C CB  1 
ATOM   11234 N N   . LEU C 1 266 ? 134.147 157.137 103.587 1.00 94.03  ? 266 LEU C N   1 
ATOM   11235 C CA  . LEU C 1 266 ? 133.514 158.073 102.660 1.00 95.89  ? 266 LEU C CA  1 
ATOM   11236 C C   . LEU C 1 266 ? 133.611 159.534 103.125 1.00 94.82  ? 266 LEU C C   1 
ATOM   11237 O O   . LEU C 1 266 ? 133.812 160.414 102.300 1.00 92.68  ? 266 LEU C O   1 
ATOM   11238 C CB  . LEU C 1 266 ? 132.062 157.642 102.418 1.00 95.50  ? 266 LEU C CB  1 
ATOM   11239 C CG  . LEU C 1 266 ? 131.909 156.288 101.698 1.00 99.04  ? 266 LEU C CG  1 
ATOM   11240 C CD1 . LEU C 1 266 ? 130.434 155.912 101.616 1.00 95.37  ? 266 LEU C CD1 1 
ATOM   11241 C CD2 . LEU C 1 266 ? 132.455 156.323 100.273 1.00 95.33  ? 266 LEU C CD2 1 
ATOM   11242 N N   . VAL C 1 267 ? 133.552 159.808 104.433 1.00 88.41  ? 267 VAL C N   1 
ATOM   11243 C CA  . VAL C 1 267 ? 133.832 161.145 104.994 1.00 86.31  ? 267 VAL C CA  1 
ATOM   11244 C C   . VAL C 1 267 ? 135.287 161.547 104.770 1.00 83.60  ? 267 VAL C C   1 
ATOM   11245 O O   . VAL C 1 267 ? 135.542 162.689 104.419 1.00 85.44  ? 267 VAL C O   1 
ATOM   11246 C CB  . VAL C 1 267 ? 133.470 161.219 106.485 1.00 79.39  ? 267 VAL C CB  1 
ATOM   11247 C CG1 . VAL C 1 267 ? 133.955 162.508 107.148 1.00 81.05  ? 267 VAL C CG1 1 
ATOM   11248 C CG2 . VAL C 1 267 ? 131.952 161.175 106.652 1.00 84.91  ? 267 VAL C CG2 1 
ATOM   11249 N N   . ILE C 1 268 ? 136.238 160.627 104.912 1.00 78.98  ? 268 ILE C N   1 
ATOM   11250 C CA  . ILE C 1 268 ? 137.659 160.857 104.641 1.00 73.75  ? 268 ILE C CA  1 
ATOM   11251 C C   . ILE C 1 268 ? 137.892 161.238 103.174 1.00 81.37  ? 268 ILE C C   1 
ATOM   11252 O O   . ILE C 1 268 ? 138.603 162.196 102.897 1.00 84.20  ? 268 ILE C O   1 
ATOM   11253 C CB  . ILE C 1 268 ? 138.452 159.610 105.080 1.00 79.17  ? 268 ILE C CB  1 
ATOM   11254 C CG1 . ILE C 1 268 ? 138.630 159.652 106.611 1.00 74.90  ? 268 ILE C CG1 1 
ATOM   11255 C CG2 . ILE C 1 268 ? 139.801 159.481 104.369 1.00 81.25  ? 268 ILE C CG2 1 
ATOM   11256 C CD1 . ILE C 1 268 ? 139.062 158.315 107.215 1.00 76.43  ? 268 ILE C CD1 1 
ATOM   11257 N N   . HIS C 1 269 ? 137.246 160.560 102.223 1.00 94.96  ? 269 HIS C N   1 
ATOM   11258 C CA  . HIS C 1 269 ? 137.322 160.945 100.812 1.00 92.26  ? 269 HIS C CA  1 
ATOM   11259 C C   . HIS C 1 269 ? 136.688 162.310 100.544 1.00 89.43  ? 269 HIS C C   1 
ATOM   11260 O O   . HIS C 1 269 ? 137.275 163.133 99.849  1.00 89.89  ? 269 HIS C O   1 
ATOM   11261 C CB  . HIS C 1 269 ? 136.680 159.873 99.926  1.00 88.74  ? 269 HIS C CB  1 
ATOM   11262 C CG  . HIS C 1 269 ? 137.555 158.662 99.754  1.00 95.88  ? 269 HIS C CG  1 
ATOM   11263 N ND1 . HIS C 1 269 ? 137.773 157.668 100.676 1.00 98.33  ? 269 HIS C ND1 1 
ATOM   11264 C CD2 . HIS C 1 269 ? 138.397 158.418 98.710  1.00 96.27  ? 269 HIS C CD2 1 
ATOM   11265 C CE1 . HIS C 1 269 ? 138.708 156.835 100.196 1.00 97.81  ? 269 HIS C CE1 1 
ATOM   11266 N NE2 . HIS C 1 269 ? 139.122 157.255 98.992  1.00 97.81  ? 269 HIS C NE2 1 
ATOM   11267 N N   . MET C 1 270 ? 135.510 162.574 101.109 1.00 85.31  ? 270 MET C N   1 
ATOM   11268 C CA  . MET C 1 270 ? 134.825 163.857 100.963 1.00 82.46  ? 270 MET C CA  1 
ATOM   11269 C C   . MET C 1 270 ? 135.636 165.015 101.552 1.00 82.81  ? 270 MET C C   1 
ATOM   11270 O O   . MET C 1 270 ? 135.764 166.062 100.926 1.00 82.60  ? 270 MET C O   1 
ATOM   11271 C CB  . MET C 1 270 ? 133.439 163.742 101.595 1.00 79.32  ? 270 MET C CB  1 
ATOM   11272 C CG  . MET C 1 270 ? 132.512 164.881 101.188 1.00 83.59  ? 270 MET C CG  1 
ATOM   11273 S SD  . MET C 1 270 ? 131.909 164.797 99.484  1.00 81.19  ? 270 MET C SD  1 
ATOM   11274 C CE  . MET C 1 270 ? 132.697 166.279 98.841  1.00 88.79  ? 270 MET C CE  1 
ATOM   11275 N N   . TYR C 1 271 ? 136.253 164.813 102.714 1.00 81.71  ? 271 TYR C N   1 
ATOM   11276 C CA  . TYR C 1 271 ? 137.129 165.779 103.368 1.00 77.50  ? 271 TYR C CA  1 
ATOM   11277 C C   . TYR C 1 271 ? 138.381 166.071 102.531 1.00 78.91  ? 271 TYR C C   1 
ATOM   11278 O O   . TYR C 1 271 ? 138.681 167.226 102.251 1.00 78.22  ? 271 TYR C O   1 
ATOM   11279 C CB  . TYR C 1 271 ? 137.483 165.221 104.752 1.00 79.14  ? 271 TYR C CB  1 
ATOM   11280 C CG  . TYR C 1 271 ? 138.201 166.182 105.669 1.00 75.78  ? 271 TYR C CG  1 
ATOM   11281 C CD1 . TYR C 1 271 ? 139.547 166.513 105.440 1.00 72.86  ? 271 TYR C CD1 1 
ATOM   11282 C CD2 . TYR C 1 271 ? 137.518 166.742 106.764 1.00 75.64  ? 271 TYR C CD2 1 
ATOM   11283 C CE1 . TYR C 1 271 ? 140.195 167.435 106.273 1.00 75.68  ? 271 TYR C CE1 1 
ATOM   11284 C CE2 . TYR C 1 271 ? 138.175 167.643 107.616 1.00 76.79  ? 271 TYR C CE2 1 
ATOM   11285 C CZ  . TYR C 1 271 ? 139.512 167.998 107.364 1.00 80.94  ? 271 TYR C CZ  1 
ATOM   11286 O OH  . TYR C 1 271 ? 140.145 168.869 108.182 1.00 79.16  ? 271 TYR C OH  1 
ATOM   11287 N N   . ASP C 1 272 ? 139.096 165.037 102.084 1.00 83.27  ? 272 ASP C N   1 
ATOM   11288 C CA  . ASP C 1 272 ? 140.302 165.185 101.270 1.00 80.53  ? 272 ASP C CA  1 
ATOM   11289 C C   . ASP C 1 272 ? 140.044 165.901 99.950  1.00 88.88  ? 272 ASP C C   1 
ATOM   11290 O O   . ASP C 1 272 ? 140.795 166.807 99.603  1.00 91.18  ? 272 ASP C O   1 
ATOM   11291 C CB  . ASP C 1 272 ? 140.918 163.819 100.962 1.00 86.28  ? 272 ASP C CB  1 
ATOM   11292 C CG  . ASP C 1 272 ? 141.706 163.214 102.119 1.00 93.60  ? 272 ASP C CG  1 
ATOM   11293 O OD1 . ASP C 1 272 ? 141.941 163.905 103.132 1.00 94.12  ? 272 ASP C OD1 1 
ATOM   11294 O OD2 . ASP C 1 272 ? 142.170 162.063 101.969 1.00 93.96  ? 272 ASP C OD2 1 
ATOM   11295 N N   . GLY C 1 273 ? 138.998 165.546 99.202  1.00 86.29  ? 273 GLY C N   1 
ATOM   11296 C CA  . GLY C 1 273 ? 138.724 166.233 97.941  1.00 77.94  ? 273 GLY C CA  1 
ATOM   11297 C C   . GLY C 1 273 ? 138.319 167.695 98.128  1.00 81.71  ? 273 GLY C C   1 
ATOM   11298 O O   . GLY C 1 273 ? 138.704 168.529 97.317  1.00 82.01  ? 273 GLY C O   1 
ATOM   11299 N N   . LEU C 1 274 ? 137.610 168.055 99.200  1.00 85.75  ? 274 LEU C N   1 
ATOM   11300 C CA  . LEU C 1 274 ? 137.330 169.457 99.520  1.00 84.59  ? 274 LEU C CA  1 
ATOM   11301 C C   . LEU C 1 274 ? 138.589 170.220 99.918  1.00 85.15  ? 274 LEU C C   1 
ATOM   11302 O O   . LEU C 1 274 ? 138.808 171.327 99.441  1.00 87.11  ? 274 LEU C O   1 
ATOM   11303 C CB  . LEU C 1 274 ? 136.325 169.539 100.672 1.00 84.30  ? 274 LEU C CB  1 
ATOM   11304 C CG  . LEU C 1 274 ? 134.890 169.183 100.287 1.00 79.88  ? 274 LEU C CG  1 
ATOM   11305 C CD1 . LEU C 1 274 ? 134.085 169.097 101.567 1.00 84.99  ? 274 LEU C CD1 1 
ATOM   11306 C CD2 . LEU C 1 274 ? 134.249 170.243 99.402  1.00 78.03  ? 274 LEU C CD2 1 
ATOM   11307 N N   . LEU C 1 275 ? 139.485 169.602 100.681 1.00 85.61  ? 275 LEU C N   1 
ATOM   11308 C CA  . LEU C 1 275 ? 140.779 170.179 101.026 1.00 83.56  ? 275 LEU C CA  1 
ATOM   11309 C C   . LEU C 1 275 ? 141.689 170.363 99.797  1.00 77.98  ? 275 LEU C C   1 
ATOM   11310 O O   . LEU C 1 275 ? 142.251 171.436 99.604  1.00 78.79  ? 275 LEU C O   1 
ATOM   11311 C CB  . LEU C 1 275 ? 141.408 169.272 102.088 1.00 80.71  ? 275 LEU C CB  1 
ATOM   11312 C CG  . LEU C 1 275 ? 142.668 169.852 102.717 1.00 78.82  ? 275 LEU C CG  1 
ATOM   11313 C CD1 . LEU C 1 275 ? 142.360 171.026 103.628 1.00 77.62  ? 275 LEU C CD1 1 
ATOM   11314 C CD2 . LEU C 1 275 ? 143.335 168.765 103.523 1.00 80.66  ? 275 LEU C CD2 1 
ATOM   11315 N N   . GLN C 1 276 ? 141.778 169.360 98.922  1.00 86.32  ? 276 GLN C N   1 
ATOM   11316 C CA  . GLN C 1 276 ? 142.463 169.460 97.632  1.00 85.04  ? 276 GLN C CA  1 
ATOM   11317 C C   . GLN C 1 276 ? 141.827 170.511 96.714  1.00 93.02  ? 276 GLN C C   1 
ATOM   11318 O O   . GLN C 1 276 ? 142.546 171.227 96.023  1.00 95.58  ? 276 GLN C O   1 
ATOM   11319 C CB  . GLN C 1 276 ? 142.472 168.095 96.933  1.00 86.48  ? 276 GLN C CB  1 
ATOM   11320 C CG  . GLN C 1 276 ? 143.366 167.054 97.621  1.00 92.30  ? 276 GLN C CG  1 
ATOM   11321 C CD  . GLN C 1 276 ? 143.138 165.638 97.086  1.00 92.88  ? 276 GLN C CD  1 
ATOM   11322 O OE1 . GLN C 1 276 ? 142.441 165.398 96.111  1.00 92.50  ? 276 GLN C OE1 1 
ATOM   11323 N NE2 . GLN C 1 276 ? 143.725 164.636 97.698  1.00 89.68  ? 276 GLN C NE2 1 
ATOM   11324 N N   . MET C 1 277 ? 140.499 170.678 96.714  1.00 101.83 ? 277 MET C N   1 
ATOM   11325 C CA  . MET C 1 277 ? 139.843 171.765 95.969  1.00 97.73  ? 277 MET C CA  1 
ATOM   11326 C C   . MET C 1 277 ? 140.097 173.142 96.588  1.00 99.00  ? 277 MET C C   1 
ATOM   11327 O O   . MET C 1 277 ? 140.298 174.106 95.857  1.00 97.69  ? 277 MET C O   1 
ATOM   11328 C CB  . MET C 1 277 ? 138.339 171.506 95.826  1.00 98.08  ? 277 MET C CB  1 
ATOM   11329 C CG  . MET C 1 277 ? 138.081 170.502 94.704  1.00 100.62 ? 277 MET C CG  1 
ATOM   11330 S SD  . MET C 1 277 ? 136.349 170.282 94.231  1.00 103.42 ? 277 MET C SD  1 
ATOM   11331 C CE  . MET C 1 277 ? 135.840 169.097 95.495  1.00 99.26  ? 277 MET C CE  1 
ATOM   11332 N N   . GLY C 1 278 ? 140.202 173.256 97.909  1.00 101.70 ? 278 GLY C N   1 
ATOM   11333 C CA  . GLY C 1 278 ? 140.658 174.476 98.571  1.00 104.06 ? 278 GLY C CA  1 
ATOM   11334 C C   . GLY C 1 278 ? 142.029 174.956 98.090  1.00 100.65 ? 278 GLY C C   1 
ATOM   11335 O O   . GLY C 1 278 ? 142.227 176.155 97.935  1.00 98.30  ? 278 GLY C O   1 
ATOM   11336 N N   . ALA C 1 279 ? 142.951 174.053 97.747  1.00 101.03 ? 279 ALA C N   1 
ATOM   11337 C CA  . ALA C 1 279 ? 144.245 174.418 97.175  1.00 100.76 ? 279 ALA C CA  1 
ATOM   11338 C C   . ALA C 1 279 ? 144.153 174.984 95.744  1.00 104.13 ? 279 ALA C C   1 
ATOM   11339 O O   . ALA C 1 279 ? 145.064 175.697 95.325  1.00 103.28 ? 279 ALA C O   1 
ATOM   11340 C CB  . ALA C 1 279 ? 145.183 173.212 97.247  1.00 99.05  ? 279 ALA C CB  1 
ATOM   11341 N N   . ARG C 1 280 ? 143.069 174.716 94.993  1.00 108.06 ? 280 ARG C N   1 
ATOM   11342 C CA  . ARG C 1 280 ? 142.784 175.373 93.701  1.00 105.91 ? 280 ARG C CA  1 
ATOM   11343 C C   . ARG C 1 280 ? 142.025 176.689 93.865  1.00 104.67 ? 280 ARG C C   1 
ATOM   11344 O O   . ARG C 1 280 ? 142.395 177.701 93.278  1.00 99.73  ? 280 ARG C O   1 
ATOM   11345 C CB  . ARG C 1 280 ? 141.967 174.463 92.769  1.00 104.87 ? 280 ARG C CB  1 
ATOM   11346 C CG  . ARG C 1 280 ? 142.558 173.071 92.536  1.00 102.45 ? 280 ARG C CG  1 
ATOM   11347 C CD  . ARG C 1 280 ? 142.008 172.442 91.249  1.00 103.35 ? 280 ARG C CD  1 
ATOM   11348 N NE  . ARG C 1 280 ? 140.531 172.394 91.192  1.00 107.39 ? 280 ARG C NE  1 
ATOM   11349 C CZ  . ARG C 1 280 ? 139.756 171.345 91.360  1.00 110.61 ? 280 ARG C CZ  1 
ATOM   11350 N NH1 . ARG C 1 280 ? 138.473 171.421 91.163  1.00 107.61 ? 280 ARG C NH1 1 
ATOM   11351 N NH2 . ARG C 1 280 ? 140.231 170.194 91.735  1.00 106.77 ? 280 ARG C NH2 1 
ATOM   11352 N N   . LEU C 1 281 ? 140.937 176.653 94.631  1.00 109.29 ? 281 LEU C N   1 
ATOM   11353 C CA  . LEU C 1 281 ? 139.915 177.702 94.708  1.00 108.79 ? 281 LEU C CA  1 
ATOM   11354 C C   . LEU C 1 281 ? 140.240 178.801 95.728  1.00 107.71 ? 281 LEU C C   1 
ATOM   11355 O O   . LEU C 1 281 ? 139.853 179.951 95.539  1.00 105.76 ? 281 LEU C O   1 
ATOM   11356 C CB  . LEU C 1 281 ? 138.575 177.033 95.062  1.00 108.14 ? 281 LEU C CB  1 
ATOM   11357 C CG  . LEU C 1 281 ? 138.100 175.969 94.061  1.00 106.33 ? 281 LEU C CG  1 
ATOM   11358 C CD1 . LEU C 1 281 ? 136.908 175.231 94.642  1.00 111.03 ? 281 LEU C CD1 1 
ATOM   11359 C CD2 . LEU C 1 281 ? 137.699 176.572 92.722  1.00 100.50 ? 281 LEU C CD2 1 
ATOM   11360 N N   . CYS C 1 282 ? 140.967 178.454 96.792  1.00 109.82 ? 282 CYS C N   1 
ATOM   11361 C CA  . CYS C 1 282 ? 141.330 179.324 97.909  1.00 109.67 ? 282 CYS C CA  1 
ATOM   11362 C C   . CYS C 1 282 ? 142.835 179.182 98.239  1.00 112.90 ? 282 CYS C C   1 
ATOM   11363 O O   . CYS C 1 282 ? 143.181 178.869 99.379  1.00 115.41 ? 282 CYS C O   1 
ATOM   11364 C CB  . CYS C 1 282 ? 140.454 178.964 99.125  1.00 110.02 ? 282 CYS C CB  1 
ATOM   11365 S SG  . CYS C 1 282 ? 138.684 179.058 98.772  1.00 117.30 ? 282 CYS C SG  1 
ATOM   11366 N N   . PRO C 1 283 ? 143.762 179.358 97.277  1.00 109.16 ? 283 PRO C N   1 
ATOM   11367 C CA  . PRO C 1 283 ? 145.126 178.835 97.386  1.00 108.02 ? 283 PRO C CA  1 
ATOM   11368 C C   . PRO C 1 283 ? 145.939 179.449 98.536  1.00 107.83 ? 283 PRO C C   1 
ATOM   11369 O O   . PRO C 1 283 ? 146.819 178.792 99.091  1.00 104.75 ? 283 PRO C O   1 
ATOM   11370 C CB  . PRO C 1 283 ? 145.769 179.119 96.025  1.00 107.57 ? 283 PRO C CB  1 
ATOM   11371 C CG  . PRO C 1 283 ? 144.969 180.296 95.469  1.00 107.46 ? 283 PRO C CG  1 
ATOM   11372 C CD  . PRO C 1 283 ? 143.566 180.033 96.003  1.00 107.52 ? 283 PRO C CD  1 
ATOM   11373 N N   . THR C 1 284 ? 145.646 180.693 98.910  1.00 110.82 ? 284 THR C N   1 
ATOM   11374 C CA  . THR C 1 284 ? 146.276 181.403 100.037 1.00 112.18 ? 284 THR C CA  1 
ATOM   11375 C C   . THR C 1 284 ? 145.649 181.093 101.403 1.00 108.37 ? 284 THR C C   1 
ATOM   11376 O O   . THR C 1 284 ? 146.160 181.559 102.423 1.00 104.00 ? 284 THR C O   1 
ATOM   11377 C CB  . THR C 1 284 ? 146.233 182.916 99.795  1.00 111.89 ? 284 THR C CB  1 
ATOM   11378 O OG1 . THR C 1 284 ? 144.904 183.344 99.599  1.00 111.16 ? 284 THR C OG1 1 
ATOM   11379 C CG2 . THR C 1 284 ? 147.034 183.330 98.565  1.00 106.16 ? 284 THR C CG2 1 
ATOM   11380 N N   . VAL C 1 285 ? 144.555 180.329 101.470 1.00 104.31 ? 285 VAL C N   1 
ATOM   11381 C CA  . VAL C 1 285 ? 143.767 180.131 102.695 1.00 103.96 ? 285 VAL C CA  1 
ATOM   11382 C C   . VAL C 1 285 ? 144.037 178.760 103.308 1.00 102.74 ? 285 VAL C C   1 
ATOM   11383 O O   . VAL C 1 285 ? 143.890 177.721 102.666 1.00 101.06 ? 285 VAL C O   1 
ATOM   11384 C CB  . VAL C 1 285 ? 142.257 180.312 102.449 1.00 103.27 ? 285 VAL C CB  1 
ATOM   11385 C CG1 . VAL C 1 285 ? 141.489 180.288 103.774 1.00 102.64 ? 285 VAL C CG1 1 
ATOM   11386 C CG2 . VAL C 1 285 ? 141.943 181.635 101.747 1.00 101.78 ? 285 VAL C CG2 1 
ATOM   11387 N N   . GLN C 1 286 ? 144.394 178.752 104.589 1.00 101.29 ? 286 GLN C N   1 
ATOM   11388 C CA  . GLN C 1 286 ? 144.577 177.544 105.389 1.00 98.47  ? 286 GLN C CA  1 
ATOM   11389 C C   . GLN C 1 286 ? 143.225 177.101 105.974 1.00 100.27 ? 286 GLN C C   1 
ATOM   11390 O O   . GLN C 1 286 ? 142.876 177.486 107.088 1.00 103.37 ? 286 GLN C O   1 
ATOM   11391 C CB  . GLN C 1 286 ? 145.622 177.837 106.480 1.00 99.06  ? 286 GLN C CB  1 
ATOM   11392 C CG  . GLN C 1 286 ? 147.017 178.219 105.953 1.00 100.75 ? 286 GLN C CG  1 
ATOM   11393 C CD  . GLN C 1 286 ? 147.825 177.021 105.478 1.00 104.13 ? 286 GLN C CD  1 
ATOM   11394 O OE1 . GLN C 1 286 ? 147.996 176.774 104.293 1.00 99.57  ? 286 GLN C OE1 1 
ATOM   11395 N NE2 . GLN C 1 286 ? 148.356 176.228 106.377 1.00 105.48 ? 286 GLN C NE2 1 
ATOM   11396 N N   . LEU C 1 287 ? 142.448 176.307 105.229 1.00 90.56  ? 287 LEU C N   1 
ATOM   11397 C CA  . LEU C 1 287 ? 141.066 175.942 105.591 1.00 82.75  ? 287 LEU C CA  1 
ATOM   11398 C C   . LEU C 1 287 ? 140.946 175.201 106.927 1.00 85.31  ? 287 LEU C C   1 
ATOM   11399 O O   . LEU C 1 287 ? 139.940 175.317 107.618 1.00 90.62  ? 287 LEU C O   1 
ATOM   11400 C CB  . LEU C 1 287 ? 140.431 175.081 104.483 1.00 82.54  ? 287 LEU C CB  1 
ATOM   11401 C CG  . LEU C 1 287 ? 140.239 175.746 103.115 1.00 86.95  ? 287 LEU C CG  1 
ATOM   11402 C CD1 . LEU C 1 287 ? 139.574 174.748 102.180 1.00 85.35  ? 287 LEU C CD1 1 
ATOM   11403 C CD2 . LEU C 1 287 ? 139.353 176.980 103.178 1.00 89.02  ? 287 LEU C CD2 1 
ATOM   11404 N N   . GLU C 1 288 ? 141.994 174.474 107.296 1.00 85.61  ? 288 GLU C N   1 
ATOM   11405 C CA  . GLU C 1 288 ? 142.114 173.778 108.570 1.00 84.13  ? 288 GLU C CA  1 
ATOM   11406 C C   . GLU C 1 288 ? 142.668 174.646 109.703 1.00 85.48  ? 288 GLU C C   1 
ATOM   11407 O O   . GLU C 1 288 ? 142.820 174.162 110.815 1.00 93.26  ? 288 GLU C O   1 
ATOM   11408 C CB  . GLU C 1 288 ? 142.995 172.549 108.390 1.00 85.80  ? 288 GLU C CB  1 
ATOM   11409 C CG  . GLU C 1 288 ? 142.415 171.577 107.374 1.00 85.92  ? 288 GLU C CG  1 
ATOM   11410 C CD  . GLU C 1 288 ? 143.218 170.285 107.389 1.00 90.38  ? 288 GLU C CD  1 
ATOM   11411 O OE1 . GLU C 1 288 ? 144.459 170.349 107.283 1.00 97.16  ? 288 GLU C OE1 1 
ATOM   11412 O OE2 . GLU C 1 288 ? 142.621 169.201 107.537 1.00 81.12  ? 288 GLU C OE2 1 
ATOM   11413 N N   . GLU C 1 289 ? 142.967 175.920 109.456 1.00 86.88  ? 289 GLU C N   1 
ATOM   11414 C CA  . GLU C 1 289 ? 143.271 176.910 110.492 1.00 87.36  ? 289 GLU C CA  1 
ATOM   11415 C C   . GLU C 1 289 ? 142.077 177.836 110.771 1.00 92.68  ? 289 GLU C C   1 
ATOM   11416 O O   . GLU C 1 289 ? 142.143 178.683 111.662 1.00 95.31  ? 289 GLU C O   1 
ATOM   11417 C CB  . GLU C 1 289 ? 144.539 177.692 110.128 1.00 91.23  ? 289 GLU C CB  1 
ATOM   11418 C CG  . GLU C 1 289 ? 145.769 176.773 110.043 1.00 95.29  ? 289 GLU C CG  1 
ATOM   11419 C CD  . GLU C 1 289 ? 147.065 177.523 109.696 1.00 96.28  ? 289 GLU C CD  1 
ATOM   11420 O OE1 . GLU C 1 289 ? 147.231 178.699 110.094 1.00 96.65  ? 289 GLU C OE1 1 
ATOM   11421 O OE2 . GLU C 1 289 ? 147.938 176.919 109.035 1.00 93.96  ? 289 GLU C OE2 1 
ATOM   11422 N N   . ILE C 1 290 ? 140.963 177.672 110.051 1.00 88.19  ? 290 ILE C N   1 
ATOM   11423 C CA  . ILE C 1 290 ? 139.703 178.373 110.312 1.00 80.59  ? 290 ILE C CA  1 
ATOM   11424 C C   . ILE C 1 290 ? 139.088 177.808 111.592 1.00 82.23  ? 290 ILE C C   1 
ATOM   11425 O O   . ILE C 1 290 ? 138.930 176.599 111.729 1.00 83.87  ? 290 ILE C O   1 
ATOM   11426 C CB  . ILE C 1 290 ? 138.740 178.278 109.108 1.00 80.69  ? 290 ILE C CB  1 
ATOM   11427 C CG1 . ILE C 1 290 ? 139.374 178.888 107.842 1.00 82.31  ? 290 ILE C CG1 1 
ATOM   11428 C CG2 . ILE C 1 290 ? 137.425 178.999 109.444 1.00 87.94  ? 290 ILE C CG2 1 
ATOM   11429 C CD1 . ILE C 1 290 ? 138.535 178.759 106.571 1.00 85.11  ? 290 ILE C CD1 1 
ATOM   11430 N N   . SER C 1 291 ? 138.734 178.679 112.532 1.00 81.42  ? 291 SER C N   1 
ATOM   11431 C CA  . SER C 1 291 ? 138.188 178.317 113.845 1.00 76.58  ? 291 SER C CA  1 
ATOM   11432 C C   . SER C 1 291 ? 136.688 178.584 113.924 1.00 83.41  ? 291 SER C C   1 
ATOM   11433 O O   . SER C 1 291 ? 136.230 179.660 113.541 1.00 81.95  ? 291 SER C O   1 
ATOM   11434 C CB  . SER C 1 291 ? 138.894 179.111 114.942 1.00 77.14  ? 291 SER C CB  1 
ATOM   11435 O OG  . SER C 1 291 ? 140.271 178.800 114.971 1.00 82.42  ? 291 SER C OG  1 
ATOM   11436 N N   . ASN C 1 292 ? 135.907 177.636 114.438 1.00 75.85  ? 292 ASN C N   1 
ATOM   11437 C CA  . ASN C 1 292 ? 134.493 177.869 114.735 1.00 70.44  ? 292 ASN C CA  1 
ATOM   11438 C C   . ASN C 1 292 ? 134.314 178.771 115.980 1.00 73.49  ? 292 ASN C C   1 
ATOM   11439 O O   . ASN C 1 292 ? 135.288 179.240 116.566 1.00 78.73  ? 292 ASN C O   1 
ATOM   11440 C CB  . ASN C 1 292 ? 133.776 176.510 114.795 1.00 70.97  ? 292 ASN C CB  1 
ATOM   11441 C CG  . ASN C 1 292 ? 134.049 175.673 116.019 1.00 67.21  ? 292 ASN C CG  1 
ATOM   11442 O OD1 . ASN C 1 292 ? 134.697 176.083 116.964 1.00 77.27  ? 292 ASN C OD1 1 
ATOM   11443 N ND2 . ASN C 1 292 ? 133.525 174.481 116.056 1.00 67.54  ? 292 ASN C ND2 1 
ATOM   11444 N N   . HIS C 1 293 ? 133.082 179.033 116.426 1.00 86.51  ? 293 HIS C N   1 
ATOM   11445 C CA  . HIS C 1 293 ? 132.835 179.914 117.578 1.00 86.22  ? 293 HIS C CA  1 
ATOM   11446 C C   . HIS C 1 293 ? 133.320 179.352 118.923 1.00 87.87  ? 293 HIS C C   1 
ATOM   11447 O O   . HIS C 1 293 ? 133.445 180.109 119.882 1.00 92.93  ? 293 HIS C O   1 
ATOM   11448 C CB  . HIS C 1 293 ? 131.347 180.267 117.650 1.00 81.07  ? 293 HIS C CB  1 
ATOM   11449 C CG  . HIS C 1 293 ? 130.805 181.062 116.488 1.00 85.83  ? 293 HIS C CG  1 
ATOM   11450 N ND1 . HIS C 1 293 ? 129.457 181.343 116.298 1.00 92.29  ? 293 HIS C ND1 1 
ATOM   11451 C CD2 . HIS C 1 293 ? 131.518 181.679 115.500 1.00 85.13  ? 293 HIS C CD2 1 
ATOM   11452 C CE1 . HIS C 1 293 ? 129.380 182.099 115.191 1.00 88.68  ? 293 HIS C CE1 1 
ATOM   11453 N NE2 . HIS C 1 293 ? 130.604 182.318 114.696 1.00 85.15  ? 293 HIS C NE2 1 
ATOM   11454 N N   . GLN C 1 294 ? 133.642 178.059 119.011 1.00 81.88  ? 294 GLN C N   1 
ATOM   11455 C CA  . GLN C 1 294 ? 134.332 177.460 120.161 1.00 82.12  ? 294 GLN C CA  1 
ATOM   11456 C C   . GLN C 1 294 ? 135.867 177.557 120.064 1.00 87.80  ? 294 GLN C C   1 
ATOM   11457 O O   . GLN C 1 294 ? 136.574 177.037 120.925 1.00 85.59  ? 294 GLN C O   1 
ATOM   11458 C CB  . GLN C 1 294 ? 133.899 175.999 120.347 1.00 84.26  ? 294 GLN C CB  1 
ATOM   11459 C CG  . GLN C 1 294 ? 132.387 175.840 120.523 1.00 88.36  ? 294 GLN C CG  1 
ATOM   11460 C CD  . GLN C 1 294 ? 131.969 174.467 121.046 1.00 92.26  ? 294 GLN C CD  1 
ATOM   11461 O OE1 . GLN C 1 294 ? 132.750 173.689 121.581 1.00 90.39  ? 294 GLN C OE1 1 
ATOM   11462 N NE2 . GLN C 1 294 ? 130.711 174.117 120.934 1.00 87.52  ? 294 GLN C NE2 1 
ATOM   11463 N N   . GLY C 1 295 ? 136.406 178.190 119.021 1.00 84.54  ? 295 GLY C N   1 
ATOM   11464 C CA  . GLY C 1 295 ? 137.843 178.301 118.769 1.00 79.75  ? 295 GLY C CA  1 
ATOM   11465 C C   . GLY C 1 295 ? 138.486 177.037 118.195 1.00 83.12  ? 295 GLY C C   1 
ATOM   11466 O O   . GLY C 1 295 ? 139.707 176.922 118.191 1.00 90.54  ? 295 GLY C O   1 
ATOM   11467 N N   . LEU C 1 296 ? 137.695 176.072 117.726 1.00 73.54  ? 296 LEU C N   1 
ATOM   11468 C CA  . LEU C 1 296 ? 138.184 174.779 117.256 1.00 66.85  ? 296 LEU C CA  1 
ATOM   11469 C C   . LEU C 1 296 ? 138.384 174.799 115.741 1.00 71.72  ? 296 LEU C C   1 
ATOM   11470 O O   . LEU C 1 296 ? 137.494 175.169 114.982 1.00 75.19  ? 296 LEU C O   1 
ATOM   11471 C CB  . LEU C 1 296 ? 137.208 173.658 117.651 1.00 66.27  ? 296 LEU C CB  1 
ATOM   11472 C CG  . LEU C 1 296 ? 136.910 173.558 119.151 1.00 67.99  ? 296 LEU C CG  1 
ATOM   11473 C CD1 . LEU C 1 296 ? 135.758 172.601 119.388 1.00 71.42  ? 296 LEU C CD1 1 
ATOM   11474 C CD2 . LEU C 1 296 ? 138.090 173.039 119.952 1.00 71.30  ? 296 LEU C CD2 1 
ATOM   11475 N N   . THR C 1 297 ? 139.548 174.353 115.290 1.00 73.82  ? 297 THR C N   1 
ATOM   11476 C CA  . THR C 1 297 ? 139.791 173.929 113.911 1.00 64.06  ? 297 THR C CA  1 
ATOM   11477 C C   . THR C 1 297 ? 139.193 172.536 113.670 1.00 63.74  ? 297 THR C C   1 
ATOM   11478 O O   . THR C 1 297 ? 138.858 171.853 114.637 1.00 66.69  ? 297 THR C O   1 
ATOM   11479 C CB  . THR C 1 297 ? 141.295 173.919 113.644 1.00 60.71  ? 297 THR C CB  1 
ATOM   11480 O OG1 . THR C 1 297 ? 141.957 173.037 114.512 1.00 69.55  ? 297 THR C OG1 1 
ATOM   11481 C CG2 . THR C 1 297 ? 141.931 175.289 113.827 1.00 58.48  ? 297 THR C CG2 1 
ATOM   11482 N N   . PRO C 1 298 ? 139.070 172.044 112.424 1.00 52.09  ? 298 PRO C N   1 
ATOM   11483 C CA  . PRO C 1 298 ? 138.572 170.698 112.157 1.00 52.09  ? 298 PRO C CA  1 
ATOM   11484 C C   . PRO C 1 298 ? 139.310 169.571 112.907 1.00 50.98  ? 298 PRO C C   1 
ATOM   11485 O O   . PRO C 1 298 ? 138.657 168.682 113.439 1.00 56.21  ? 298 PRO C O   1 
ATOM   11486 C CB  . PRO C 1 298 ? 138.676 170.534 110.644 1.00 61.02  ? 298 PRO C CB  1 
ATOM   11487 C CG  . PRO C 1 298 ? 138.553 171.954 110.118 1.00 54.05  ? 298 PRO C CG  1 
ATOM   11488 C CD  . PRO C 1 298 ? 139.273 172.767 111.181 1.00 57.41  ? 298 PRO C CD  1 
ATOM   11489 N N   . LEU C 1 299 ? 140.641 169.619 113.036 1.00 54.58  ? 299 LEU C N   1 
ATOM   11490 C CA  . LEU C 1 299 ? 141.417 168.632 113.803 1.00 57.38  ? 299 LEU C CA  1 
ATOM   11491 C C   . LEU C 1 299 ? 141.099 168.677 115.303 1.00 67.24  ? 299 LEU C C   1 
ATOM   11492 O O   . LEU C 1 299 ? 140.905 167.640 115.931 1.00 69.74  ? 299 LEU C O   1 
ATOM   11493 C CB  . LEU C 1 299 ? 142.922 168.847 113.552 1.00 56.18  ? 299 LEU C CB  1 
ATOM   11494 C CG  . LEU C 1 299 ? 143.847 167.890 114.338 1.00 49.48  ? 299 LEU C CG  1 
ATOM   11495 C CD1 . LEU C 1 299 ? 143.673 166.438 113.933 1.00 57.77  ? 299 LEU C CD1 1 
ATOM   11496 C CD2 . LEU C 1 299 ? 145.301 168.258 114.122 1.00 61.32  ? 299 LEU C CD2 1 
ATOM   11497 N N   . LYS C 1 300 ? 141.013 169.876 115.886 1.00 70.45  ? 300 LYS C N   1 
ATOM   11498 C CA  . LYS C 1 300 ? 140.655 170.068 117.298 1.00 55.05  ? 300 LYS C CA  1 
ATOM   11499 C C   . LYS C 1 300 ? 139.214 169.650 117.584 1.00 60.99  ? 300 LYS C C   1 
ATOM   11500 O O   . LYS C 1 300 ? 138.945 169.064 118.622 1.00 74.73  ? 300 LYS C O   1 
ATOM   11501 C CB  . LYS C 1 300 ? 140.872 171.531 117.691 1.00 62.06  ? 300 LYS C CB  1 
ATOM   11502 C CG  . LYS C 1 300 ? 142.348 171.924 117.764 1.00 55.44  ? 300 LYS C CG  1 
ATOM   11503 C CD  . LYS C 1 300 ? 142.480 173.355 118.282 1.00 57.92  ? 300 LYS C CD  1 
ATOM   11504 C CE  . LYS C 1 300 ? 143.931 173.813 118.211 1.00 64.44  ? 300 LYS C CE  1 
ATOM   11505 N NZ  . LYS C 1 300 ? 144.116 175.142 118.836 1.00 66.28  ? 300 LYS C NZ  1 
ATOM   11506 N N   . LEU C 1 301 ? 138.290 169.897 116.662 1.00 60.57  ? 301 LEU C N   1 
ATOM   11507 C CA  . LEU C 1 301 ? 136.912 169.432 116.757 1.00 65.04  ? 301 LEU C CA  1 
ATOM   11508 C C   . LEU C 1 301 ? 136.811 167.905 116.683 1.00 67.85  ? 301 LEU C C   1 
ATOM   11509 O O   . LEU C 1 301 ? 136.043 167.316 117.432 1.00 72.17  ? 301 LEU C O   1 
ATOM   11510 C CB  . LEU C 1 301 ? 136.088 170.128 115.665 1.00 60.38  ? 301 LEU C CB  1 
ATOM   11511 C CG  . LEU C 1 301 ? 134.597 169.781 115.680 1.00 50.36  ? 301 LEU C CG  1 
ATOM   11512 C CD1 . LEU C 1 301 ? 133.896 170.287 116.931 1.00 57.87  ? 301 LEU C CD1 1 
ATOM   11513 C CD2 . LEU C 1 301 ? 133.924 170.427 114.486 1.00 56.24  ? 301 LEU C CD2 1 
ATOM   11514 N N   . ALA C 1 302 ? 137.613 167.233 115.860 1.00 64.16  ? 302 ALA C N   1 
ATOM   11515 C CA  . ALA C 1 302 ? 137.627 165.775 115.798 1.00 46.81  ? 302 ALA C CA  1 
ATOM   11516 C C   . ALA C 1 302 ? 138.090 165.130 117.117 1.00 62.83  ? 302 ALA C C   1 
ATOM   11517 O O   . ALA C 1 302 ? 137.578 164.080 117.484 1.00 72.14  ? 302 ALA C O   1 
ATOM   11518 C CB  . ALA C 1 302 ? 138.483 165.354 114.604 1.00 44.06  ? 302 ALA C CB  1 
ATOM   11519 N N   . ALA C 1 303 ? 138.990 165.780 117.861 1.00 69.16  ? 303 ALA C N   1 
ATOM   11520 C CA  . ALA C 1 303 ? 139.424 165.403 119.202 1.00 57.75  ? 303 ALA C CA  1 
ATOM   11521 C C   . ALA C 1 303 ? 138.349 165.647 120.273 1.00 68.14  ? 303 ALA C C   1 
ATOM   11522 O O   . ALA C 1 303 ? 138.064 164.753 121.065 1.00 73.68  ? 303 ALA C O   1 
ATOM   11523 C CB  . ALA C 1 303 ? 140.701 166.179 119.514 1.00 58.19  ? 303 ALA C CB  1 
ATOM   11524 N N   . LYS C 1 304 ? 137.695 166.814 120.270 1.00 68.36  ? 304 LYS C N   1 
ATOM   11525 C CA  . LYS C 1 304 ? 136.648 167.143 121.243 1.00 58.28  ? 304 LYS C CA  1 
ATOM   11526 C C   . LYS C 1 304 ? 135.409 166.264 121.087 1.00 67.84  ? 304 LYS C C   1 
ATOM   11527 O O   . LYS C 1 304 ? 134.857 165.789 122.073 1.00 72.79  ? 304 LYS C O   1 
ATOM   11528 C CB  . LYS C 1 304 ? 136.304 168.630 121.140 1.00 60.71  ? 304 LYS C CB  1 
ATOM   11529 C CG  . LYS C 1 304 ? 135.478 169.059 122.352 1.00 76.65  ? 304 LYS C CG  1 
ATOM   11530 C CD  . LYS C 1 304 ? 135.209 170.557 122.339 1.00 77.53  ? 304 LYS C CD  1 
ATOM   11531 C CE  . LYS C 1 304 ? 134.436 170.971 123.590 1.00 75.00  ? 304 LYS C CE  1 
ATOM   11532 N NZ  . LYS C 1 304 ? 134.223 172.437 123.626 1.00 79.10  ? 304 LYS C NZ  1 
ATOM   11533 N N   . GLU C 1 305 ? 135.003 165.994 119.854 1.00 76.41  ? 305 GLU C N   1 
ATOM   11534 C CA  . GLU C 1 305 ? 133.893 165.096 119.521 1.00 71.04  ? 305 GLU C CA  1 
ATOM   11535 C C   . GLU C 1 305 ? 134.286 163.606 119.533 1.00 72.89  ? 305 GLU C C   1 
ATOM   11536 O O   . GLU C 1 305 ? 133.423 162.744 119.407 1.00 74.73  ? 305 GLU C O   1 
ATOM   11537 C CB  . GLU C 1 305 ? 133.299 165.516 118.170 1.00 67.51  ? 305 GLU C CB  1 
ATOM   11538 C CG  . GLU C 1 305 ? 132.722 166.938 118.168 1.00 72.79  ? 305 GLU C CG  1 
ATOM   11539 C CD  . GLU C 1 305 ? 131.553 167.118 119.149 1.00 81.16  ? 305 GLU C CD  1 
ATOM   11540 O OE1 . GLU C 1 305 ? 130.640 166.262 119.168 1.00 83.44  ? 305 GLU C OE1 1 
ATOM   11541 O OE2 . GLU C 1 305 ? 131.532 168.123 119.895 1.00 80.80  ? 305 GLU C OE2 1 
ATOM   11542 N N   . GLY C 1 306 ? 135.569 163.276 119.703 1.00 64.84  ? 306 GLY C N   1 
ATOM   11543 C CA  . GLY C 1 306 ? 136.051 161.903 119.855 1.00 60.32  ? 306 GLY C CA  1 
ATOM   11544 C C   . GLY C 1 306 ? 135.975 161.047 118.600 1.00 61.33  ? 306 GLY C C   1 
ATOM   11545 O O   . GLY C 1 306 ? 135.793 159.838 118.696 1.00 70.80  ? 306 GLY C O   1 
ATOM   11546 N N   . LYS C 1 307 ? 136.055 161.645 117.414 1.00 67.75  ? 307 LYS C N   1 
ATOM   11547 C CA  . LYS C 1 307 ? 135.876 160.965 116.126 1.00 71.25  ? 307 LYS C CA  1 
ATOM   11548 C C   . LYS C 1 307 ? 137.178 160.314 115.665 1.00 76.03  ? 307 LYS C C   1 
ATOM   11549 O O   . LYS C 1 307 ? 137.858 160.870 114.813 1.00 74.27  ? 307 LYS C O   1 
ATOM   11550 C CB  . LYS C 1 307 ? 135.326 161.958 115.087 1.00 61.65  ? 307 LYS C CB  1 
ATOM   11551 C CG  . LYS C 1 307 ? 134.053 162.710 115.478 1.00 69.65  ? 307 LYS C CG  1 
ATOM   11552 C CD  . LYS C 1 307 ? 132.909 161.766 115.856 1.00 70.03  ? 307 LYS C CD  1 
ATOM   11553 C CE  . LYS C 1 307 ? 131.604 162.521 116.095 1.00 67.05  ? 307 LYS C CE  1 
ATOM   11554 N NZ  . LYS C 1 307 ? 131.056 163.064 114.836 1.00 70.21  ? 307 LYS C NZ  1 
ATOM   11555 N N   . ILE C 1 308 ? 137.564 159.161 116.210 1.00 79.20  ? 308 ILE C N   1 
ATOM   11556 C CA  . ILE C 1 308 ? 138.924 158.612 116.029 1.00 69.61  ? 308 ILE C CA  1 
ATOM   11557 C C   . ILE C 1 308 ? 139.310 158.444 114.557 1.00 69.38  ? 308 ILE C C   1 
ATOM   11558 O O   . ILE C 1 308 ? 140.439 158.732 114.197 1.00 78.62  ? 308 ILE C O   1 
ATOM   11559 C CB  . ILE C 1 308 ? 139.130 157.263 116.753 1.00 73.81  ? 308 ILE C CB  1 
ATOM   11560 C CG1 . ILE C 1 308 ? 138.711 157.284 118.227 1.00 75.52  ? 308 ILE C CG1 1 
ATOM   11561 C CG2 . ILE C 1 308 ? 140.610 156.839 116.688 1.00 73.72  ? 308 ILE C CG2 1 
ATOM   11562 C CD1 . ILE C 1 308 ? 138.404 155.870 118.725 1.00 82.24  ? 308 ILE C CD1 1 
ATOM   11563 N N   . GLU C 1 309 ? 138.407 157.995 113.687 1.00 77.67  ? 309 GLU C N   1 
ATOM   11564 C CA  . GLU C 1 309 ? 138.769 157.656 112.306 1.00 77.85  ? 309 GLU C CA  1 
ATOM   11565 C C   . GLU C 1 309 ? 139.147 158.876 111.462 1.00 76.16  ? 309 GLU C C   1 
ATOM   11566 O O   . GLU C 1 309 ? 140.196 158.886 110.823 1.00 76.94  ? 309 GLU C O   1 
ATOM   11567 C CB  . GLU C 1 309 ? 137.624 156.893 111.627 1.00 82.19  ? 309 GLU C CB  1 
ATOM   11568 C CG  . GLU C 1 309 ? 137.176 155.611 112.344 1.00 85.28  ? 309 GLU C CG  1 
ATOM   11569 C CD  . GLU C 1 309 ? 138.304 154.597 112.580 1.00 87.52  ? 309 GLU C CD  1 
ATOM   11570 O OE1 . GLU C 1 309 ? 139.337 154.643 111.873 1.00 85.71  ? 309 GLU C OE1 1 
ATOM   11571 O OE2 . GLU C 1 309 ? 138.173 153.740 113.481 1.00 85.86  ? 309 GLU C OE2 1 
ATOM   11572 N N   . ILE C 1 310 ? 138.332 159.932 111.477 1.00 68.10  ? 310 ILE C N   1 
ATOM   11573 C CA  . ILE C 1 310 ? 138.668 161.196 110.816 1.00 64.45  ? 310 ILE C CA  1 
ATOM   11574 C C   . ILE C 1 310 ? 139.789 161.936 111.551 1.00 70.81  ? 310 ILE C C   1 
ATOM   11575 O O   . ILE C 1 310 ? 140.624 162.552 110.900 1.00 72.43  ? 310 ILE C O   1 
ATOM   11576 C CB  . ILE C 1 310 ? 137.408 162.052 110.562 1.00 65.48  ? 310 ILE C CB  1 
ATOM   11577 C CG1 . ILE C 1 310 ? 137.665 163.331 109.737 1.00 72.32  ? 310 ILE C CG1 1 
ATOM   11578 C CG2 . ILE C 1 310 ? 136.718 162.469 111.864 1.00 67.34  ? 310 ILE C CG2 1 
ATOM   11579 C CD1 . ILE C 1 310 ? 138.221 163.079 108.332 1.00 75.07  ? 310 ILE C CD1 1 
ATOM   11580 N N   . PHE C 1 311 ? 139.889 161.834 112.881 1.00 72.85  ? 311 PHE C N   1 
ATOM   11581 C CA  . PHE C 1 311 ? 140.999 162.391 113.658 1.00 60.87  ? 311 PHE C CA  1 
ATOM   11582 C C   . PHE C 1 311 ? 142.343 161.785 113.244 1.00 63.63  ? 311 PHE C C   1 
ATOM   11583 O O   . PHE C 1 311 ? 143.236 162.508 112.823 1.00 66.20  ? 311 PHE C O   1 
ATOM   11584 C CB  . PHE C 1 311 ? 140.733 162.176 115.151 1.00 54.92  ? 311 PHE C CB  1 
ATOM   11585 C CG  . PHE C 1 311 ? 141.853 162.651 116.045 1.00 62.62  ? 311 PHE C CG  1 
ATOM   11586 C CD1 . PHE C 1 311 ? 142.138 164.022 116.130 1.00 62.92  ? 311 PHE C CD1 1 
ATOM   11587 C CD2 . PHE C 1 311 ? 142.624 161.732 116.777 1.00 63.78  ? 311 PHE C CD2 1 
ATOM   11588 C CE1 . PHE C 1 311 ? 143.197 164.475 116.919 1.00 58.24  ? 311 PHE C CE1 1 
ATOM   11589 C CE2 . PHE C 1 311 ? 143.688 162.183 117.566 1.00 63.66  ? 311 PHE C CE2 1 
ATOM   11590 C CZ  . PHE C 1 311 ? 143.976 163.551 117.627 1.00 65.50  ? 311 PHE C CZ  1 
ATOM   11591 N N   . ARG C 1 312 ? 142.461 160.452 113.275 1.00 66.67  ? 312 ARG C N   1 
ATOM   11592 C CA  . ARG C 1 312 ? 143.618 159.686 112.805 1.00 58.49  ? 312 ARG C CA  1 
ATOM   11593 C C   . ARG C 1 312 ? 143.981 160.040 111.378 1.00 67.40  ? 312 ARG C C   1 
ATOM   11594 O O   . ARG C 1 312 ? 145.152 160.260 111.097 1.00 75.74  ? 312 ARG C O   1 
ATOM   11595 C CB  . ARG C 1 312 ? 143.298 158.191 112.929 1.00 63.19  ? 312 ARG C CB  1 
ATOM   11596 C CG  . ARG C 1 312 ? 144.353 157.291 112.275 1.00 65.41  ? 312 ARG C CG  1 
ATOM   11597 C CD  . ARG C 1 312 ? 144.322 155.858 112.798 1.00 73.05  ? 312 ARG C CD  1 
ATOM   11598 N NE  . ARG C 1 312 ? 142.989 155.232 112.753 1.00 78.77  ? 312 ARG C NE  1 
ATOM   11599 C CZ  . ARG C 1 312 ? 142.634 154.155 113.429 1.00 79.62  ? 312 ARG C CZ  1 
ATOM   11600 N NH1 . ARG C 1 312 ? 141.440 153.666 113.330 1.00 74.59  ? 312 ARG C NH1 1 
ATOM   11601 N NH2 . ARG C 1 312 ? 143.460 153.529 114.212 1.00 77.07  ? 312 ARG C NH2 1 
ATOM   11602 N N   . HIS C 1 313 ? 143.004 160.118 110.480 1.00 64.93  ? 313 HIS C N   1 
ATOM   11603 C CA  . HIS C 1 313 ? 143.266 160.473 109.095 1.00 53.76  ? 313 HIS C CA  1 
ATOM   11604 C C   . HIS C 1 313 ? 143.871 161.863 108.962 1.00 62.15  ? 313 HIS C C   1 
ATOM   11605 O O   . HIS C 1 313 ? 144.934 161.978 108.371 1.00 75.48  ? 313 HIS C O   1 
ATOM   11606 C CB  . HIS C 1 313 ? 142.002 160.348 108.259 1.00 67.91  ? 313 HIS C CB  1 
ATOM   11607 C CG  . HIS C 1 313 ? 142.268 160.777 106.843 1.00 74.71  ? 313 HIS C CG  1 
ATOM   11608 N ND1 . HIS C 1 313 ? 143.025 160.060 105.916 1.00 67.33  ? 313 HIS C ND1 1 
ATOM   11609 C CD2 . HIS C 1 313 ? 141.936 161.986 106.313 1.00 68.19  ? 313 HIS C CD2 1 
ATOM   11610 C CE1 . HIS C 1 313 ? 143.120 160.855 104.840 1.00 65.28  ? 313 HIS C CE1 1 
ATOM   11611 N NE2 . HIS C 1 313 ? 142.485 162.013 105.058 1.00 60.32  ? 313 HIS C NE2 1 
ATOM   11612 N N   . ILE C 1 314 ? 143.268 162.913 109.527 1.00 62.98  ? 314 ILE C N   1 
ATOM   11613 C CA  . ILE C 1 314 ? 143.811 164.276 109.441 1.00 63.52  ? 314 ILE C CA  1 
ATOM   11614 C C   . ILE C 1 314 ? 145.226 164.317 110.023 1.00 57.93  ? 314 ILE C C   1 
ATOM   11615 O O   . ILE C 1 314 ? 146.153 164.809 109.390 1.00 68.08  ? 314 ILE C O   1 
ATOM   11616 C CB  . ILE C 1 314 ? 142.890 165.293 110.154 1.00 68.48  ? 314 ILE C CB  1 
ATOM   11617 C CG1 . ILE C 1 314 ? 141.501 165.397 109.492 1.00 61.78  ? 314 ILE C CG1 1 
ATOM   11618 C CG2 . ILE C 1 314 ? 143.536 166.690 110.163 1.00 63.16  ? 314 ILE C CG2 1 
ATOM   11619 C CD1 . ILE C 1 314 ? 140.449 166.037 110.402 1.00 58.04  ? 314 ILE C CD1 1 
ATOM   11620 N N   . LEU C 1 315 ? 145.400 163.757 111.217 1.00 54.75  ? 315 LEU C N   1 
ATOM   11621 C CA  . LEU C 1 315 ? 146.625 163.776 112.009 1.00 56.71  ? 315 LEU C CA  1 
ATOM   11622 C C   . LEU C 1 315 ? 147.829 163.139 111.292 1.00 60.42  ? 315 LEU C C   1 
ATOM   11623 O O   . LEU C 1 315 ? 148.947 163.632 111.405 1.00 58.37  ? 315 LEU C O   1 
ATOM   11624 C CB  . LEU C 1 315 ? 146.258 163.040 113.304 1.00 55.72  ? 315 LEU C CB  1 
ATOM   11625 C CG  . LEU C 1 315 ? 147.340 162.970 114.370 1.00 55.74  ? 315 LEU C CG  1 
ATOM   11626 C CD1 . LEU C 1 315 ? 147.437 164.307 115.095 1.00 60.48  ? 315 LEU C CD1 1 
ATOM   11627 C CD2 . LEU C 1 315 ? 146.979 161.866 115.353 1.00 53.29  ? 315 LEU C CD2 1 
ATOM   11628 N N   . GLN C 1 316 ? 147.606 162.061 110.545 1.00 66.47  ? 316 GLN C N   1 
ATOM   11629 C CA  . GLN C 1 316 ? 148.634 161.262 109.876 1.00 55.56  ? 316 GLN C CA  1 
ATOM   11630 C C   . GLN C 1 316 ? 148.674 161.450 108.350 1.00 56.46  ? 316 GLN C C   1 
ATOM   11631 O O   . GLN C 1 316 ? 149.338 160.690 107.654 1.00 64.01  ? 316 GLN C O   1 
ATOM   11632 C CB  . GLN C 1 316 ? 148.425 159.784 110.234 1.00 54.70  ? 316 GLN C CB  1 
ATOM   11633 C CG  . GLN C 1 316 ? 148.411 159.521 111.744 1.00 64.50  ? 316 GLN C CG  1 
ATOM   11634 C CD  . GLN C 1 316 ? 148.263 158.047 112.090 1.00 64.88  ? 316 GLN C CD  1 
ATOM   11635 O OE1 . GLN C 1 316 ? 147.912 157.207 111.278 1.00 68.29  ? 316 GLN C OE1 1 
ATOM   11636 N NE2 . GLN C 1 316 ? 148.533 157.676 113.316 1.00 66.15  ? 316 GLN C NE2 1 
ATOM   11637 N N   . ARG C 1 317 ? 147.953 162.429 107.805 1.00 62.04  ? 317 ARG C N   1 
ATOM   11638 C CA  . ARG C 1 317 ? 147.716 162.597 106.365 1.00 63.86  ? 317 ARG C CA  1 
ATOM   11639 C C   . ARG C 1 317 ? 148.992 162.831 105.566 1.00 72.51  ? 317 ARG C C   1 
ATOM   11640 O O   . ARG C 1 317 ? 149.761 163.728 105.896 1.00 77.90  ? 317 ARG C O   1 
ATOM   11641 C CB  . ARG C 1 317 ? 146.754 163.771 106.199 1.00 60.09  ? 317 ARG C CB  1 
ATOM   11642 C CG  . ARG C 1 317 ? 146.190 163.896 104.785 1.00 67.35  ? 317 ARG C CG  1 
ATOM   11643 C CD  . ARG C 1 317 ? 145.094 164.959 104.782 1.00 72.03  ? 317 ARG C CD  1 
ATOM   11644 N NE  . ARG C 1 317 ? 145.639 166.273 105.152 1.00 71.96  ? 317 ARG C NE  1 
ATOM   11645 C CZ  . ARG C 1 317 ? 145.119 167.163 105.962 1.00 66.89  ? 317 ARG C CZ  1 
ATOM   11646 N NH1 . ARG C 1 317 ? 145.774 168.245 106.213 1.00 60.17  ? 317 ARG C NH1 1 
ATOM   11647 N NH2 . ARG C 1 317 ? 143.949 167.017 106.489 1.00 70.51  ? 317 ARG C NH2 1 
ATOM   11648 N N   . GLU C 1 318 ? 149.182 162.102 104.473 1.00 76.44  ? 318 GLU C N   1 
ATOM   11649 C CA  . GLU C 1 318 ? 150.327 162.226 103.569 1.00 72.94  ? 318 GLU C CA  1 
ATOM   11650 C C   . GLU C 1 318 ? 149.870 162.219 102.106 1.00 81.31  ? 318 GLU C C   1 
ATOM   11651 O O   . GLU C 1 318 ? 149.063 161.374 101.719 1.00 77.91  ? 318 GLU C O   1 
ATOM   11652 C CB  . GLU C 1 318 ? 151.309 161.085 103.870 1.00 78.10  ? 318 GLU C CB  1 
ATOM   11653 C CG  . GLU C 1 318 ? 152.611 161.143 103.060 1.00 83.41  ? 318 GLU C CG  1 
ATOM   11654 C CD  . GLU C 1 318 ? 153.649 160.132 103.566 1.00 85.16  ? 318 GLU C CD  1 
ATOM   11655 O OE1 . GLU C 1 318 ? 153.259 159.030 104.006 1.00 87.02  ? 318 GLU C OE1 1 
ATOM   11656 O OE2 . GLU C 1 318 ? 154.871 160.408 103.486 1.00 84.73  ? 318 GLU C OE2 1 
ATOM   11657 N N   . PHE C 1 319 ? 150.407 163.120 101.283 1.00 92.69  ? 319 PHE C N   1 
ATOM   11658 C CA  . PHE C 1 319 ? 150.139 163.221 99.846  1.00 84.22  ? 319 PHE C CA  1 
ATOM   11659 C C   . PHE C 1 319 ? 151.439 163.376 99.045  1.00 89.26  ? 319 PHE C C   1 
ATOM   11660 O O   . PHE C 1 319 ? 152.462 163.812 99.571  1.00 89.18  ? 319 PHE C O   1 
ATOM   11661 C CB  . PHE C 1 319 ? 149.227 164.419 99.554  1.00 80.64  ? 319 PHE C CB  1 
ATOM   11662 C CG  . PHE C 1 319 ? 147.835 164.396 100.144 1.00 85.90  ? 319 PHE C CG  1 
ATOM   11663 C CD1 . PHE C 1 319 ? 146.930 163.368 99.823  1.00 90.44  ? 319 PHE C CD1 1 
ATOM   11664 C CD2 . PHE C 1 319 ? 147.413 165.458 100.947 1.00 84.74  ? 319 PHE C CD2 1 
ATOM   11665 C CE1 . PHE C 1 319 ? 145.612 163.414 100.310 1.00 88.60  ? 319 PHE C CE1 1 
ATOM   11666 C CE2 . PHE C 1 319 ? 146.092 165.516 101.416 1.00 84.03  ? 319 PHE C CE2 1 
ATOM   11667 C CZ  . PHE C 1 319 ? 145.190 164.493 101.100 1.00 86.64  ? 319 PHE C CZ  1 
ATOM   11668 N N   . SER C 1 320 ? 151.381 163.078 97.748  1.00 111.39 ? 320 SER C N   1 
ATOM   11669 C CA  . SER C 1 320 ? 152.478 163.243 96.788  1.00 112.20 ? 320 SER C CA  1 
ATOM   11670 C C   . SER C 1 320 ? 152.065 164.147 95.621  1.00 113.00 ? 320 SER C C   1 
ATOM   11671 O O   . SER C 1 320 ? 150.883 164.285 95.302  1.00 110.26 ? 320 SER C O   1 
ATOM   11672 C CB  . SER C 1 320 ? 152.962 161.877 96.294  1.00 108.90 ? 320 SER C CB  1 
ATOM   11673 O OG  . SER C 1 320 ? 151.929 161.193 95.610  1.00 110.02 ? 320 SER C OG  1 
ATOM   11674 N N   . GLY C 1 321 ? 153.033 164.809 94.990  1.00 107.71 ? 321 GLY C N   1 
ATOM   11675 C CA  . GLY C 1 321 ? 152.767 165.701 93.860  1.00 106.63 ? 321 GLY C CA  1 
ATOM   11676 C C   . GLY C 1 321 ? 152.172 167.051 94.289  1.00 108.95 ? 321 GLY C C   1 
ATOM   11677 O O   . GLY C 1 321 ? 152.654 167.624 95.270  1.00 110.26 ? 321 GLY C O   1 
ATOM   11678 N N   . PRO C 1 322 ? 151.155 167.596 93.589  1.00 109.84 ? 322 PRO C N   1 
ATOM   11679 C CA  . PRO C 1 322 ? 150.640 168.951 93.807  1.00 109.59 ? 322 PRO C CA  1 
ATOM   11680 C C   . PRO C 1 322 ? 150.194 169.255 95.243  1.00 107.78 ? 322 PRO C C   1 
ATOM   11681 O O   . PRO C 1 322 ? 150.328 170.383 95.711  1.00 106.29 ? 322 PRO C O   1 
ATOM   11682 C CB  . PRO C 1 322 ? 149.443 169.080 92.858  1.00 109.17 ? 322 PRO C CB  1 
ATOM   11683 C CG  . PRO C 1 322 ? 149.757 168.107 91.732  1.00 106.48 ? 322 PRO C CG  1 
ATOM   11684 C CD  . PRO C 1 322 ? 150.499 166.984 92.443  1.00 107.60 ? 322 PRO C CD  1 
ATOM   11685 N N   . TYR C 1 323 ? 149.706 168.228 95.937  1.00 93.97  ? 323 TYR C N   1 
ATOM   11686 C CA  . TYR C 1 323 ? 149.065 168.315 97.241  1.00 95.23  ? 323 TYR C CA  1 
ATOM   11687 C C   . TYR C 1 323 ? 149.987 168.037 98.432  1.00 93.23  ? 323 TYR C C   1 
ATOM   11688 O O   . TYR C 1 323 ? 149.508 167.980 99.559  1.00 97.11  ? 323 TYR C O   1 
ATOM   11689 C CB  . TYR C 1 323 ? 147.849 167.378 97.216  1.00 100.69 ? 323 TYR C CB  1 
ATOM   11690 C CG  . TYR C 1 323 ? 146.888 167.663 96.077  1.00 96.90  ? 323 TYR C CG  1 
ATOM   11691 C CD1 . TYR C 1 323 ? 146.454 168.980 95.821  1.00 96.31  ? 323 TYR C CD1 1 
ATOM   11692 C CD2 . TYR C 1 323 ? 146.452 166.613 95.250  1.00 94.79  ? 323 TYR C CD2 1 
ATOM   11693 C CE1 . TYR C 1 323 ? 145.618 169.254 94.724  1.00 94.85  ? 323 TYR C CE1 1 
ATOM   11694 C CE2 . TYR C 1 323 ? 145.608 166.882 94.157  1.00 98.54  ? 323 TYR C CE2 1 
ATOM   11695 C CZ  . TYR C 1 323 ? 145.200 168.202 93.887  1.00 98.17  ? 323 TYR C CZ  1 
ATOM   11696 O OH  . TYR C 1 323 ? 144.400 168.462 92.824  1.00 96.58  ? 323 TYR C OH  1 
ATOM   11697 N N   . GLN C 1 324 ? 151.302 167.898 98.246  1.00 92.57  ? 324 GLN C N   1 
ATOM   11698 C CA  . GLN C 1 324 ? 152.214 167.613 99.357  1.00 93.37  ? 324 GLN C CA  1 
ATOM   11699 C C   . GLN C 1 324 ? 152.086 168.587 100.558 1.00 93.55  ? 324 GLN C C   1 
ATOM   11700 O O   . GLN C 1 324 ? 152.033 168.086 101.678 1.00 92.85  ? 324 GLN C O   1 
ATOM   11701 C CB  . GLN C 1 324 ? 153.652 167.455 98.836  1.00 91.33  ? 324 GLN C CB  1 
ATOM   11702 C CG  . GLN C 1 324 ? 154.642 167.091 99.947  1.00 95.55  ? 324 GLN C CG  1 
ATOM   11703 C CD  . GLN C 1 324 ? 156.023 166.717 99.419  1.00 96.39  ? 324 GLN C CD  1 
ATOM   11704 O OE1 . GLN C 1 324 ? 156.498 167.222 98.421  1.00 95.87  ? 324 GLN C OE1 1 
ATOM   11705 N NE2 . GLN C 1 324 ? 156.728 165.825 100.058 1.00 94.68  ? 324 GLN C NE2 1 
ATOM   11706 N N   . PRO C 1 325 ? 151.945 169.920 100.401 1.00 88.38  ? 325 PRO C N   1 
ATOM   11707 C CA  . PRO C 1 325 ? 151.742 170.860 101.506 1.00 88.71  ? 325 PRO C CA  1 
ATOM   11708 C C   . PRO C 1 325 ? 150.469 170.646 102.337 1.00 86.62  ? 325 PRO C C   1 
ATOM   11709 O O   . PRO C 1 325 ? 150.385 171.137 103.456 1.00 89.31  ? 325 PRO C O   1 
ATOM   11710 C CB  . PRO C 1 325 ? 151.721 172.250 100.868 1.00 87.59  ? 325 PRO C CB  1 
ATOM   11711 C CG  . PRO C 1 325 ? 152.551 172.071 99.609  1.00 88.74  ? 325 PRO C CG  1 
ATOM   11712 C CD  . PRO C 1 325 ? 152.178 170.663 99.172  1.00 85.54  ? 325 PRO C CD  1 
ATOM   11713 N N   . LEU C 1 326 ? 149.488 169.909 101.809 1.00 82.88  ? 326 LEU C N   1 
ATOM   11714 C CA  . LEU C 1 326 ? 148.299 169.494 102.550 1.00 81.48  ? 326 LEU C CA  1 
ATOM   11715 C C   . LEU C 1 326 ? 148.583 168.299 103.473 1.00 83.38  ? 326 LEU C C   1 
ATOM   11716 O O   . LEU C 1 326 ? 147.718 167.912 104.250 1.00 83.24  ? 326 LEU C O   1 
ATOM   11717 C CB  . LEU C 1 326 ? 147.142 169.188 101.581 1.00 80.38  ? 326 LEU C CB  1 
ATOM   11718 C CG  . LEU C 1 326 ? 146.780 170.307 100.596 1.00 78.88  ? 326 LEU C CG  1 
ATOM   11719 C CD1 . LEU C 1 326 ? 145.669 169.814 99.685  1.00 82.14  ? 326 LEU C CD1 1 
ATOM   11720 C CD2 . LEU C 1 326 ? 146.311 171.569 101.304 1.00 79.38  ? 326 LEU C CD2 1 
ATOM   11721 N N   . SER C 1 327 ? 149.769 167.694 103.422 1.00 79.70  ? 327 SER C N   1 
ATOM   11722 C CA  . SER C 1 327 ? 150.180 166.644 104.357 1.00 76.74  ? 327 SER C CA  1 
ATOM   11723 C C   . SER C 1 327 ? 150.386 167.196 105.766 1.00 75.60  ? 327 SER C C   1 
ATOM   11724 O O   . SER C 1 327 ? 150.814 168.336 105.947 1.00 71.05  ? 327 SER C O   1 
ATOM   11725 C CB  . SER C 1 327 ? 151.486 165.983 103.926 1.00 70.26  ? 327 SER C CB  1 
ATOM   11726 O OG  . SER C 1 327 ? 151.444 165.590 102.578 1.00 69.84  ? 327 SER C OG  1 
ATOM   11727 N N   . ARG C 1 328 ? 150.146 166.352 106.770 1.00 70.08  ? 328 ARG C N   1 
ATOM   11728 C CA  . ARG C 1 328 ? 150.675 166.509 108.128 1.00 63.43  ? 328 ARG C CA  1 
ATOM   11729 C C   . ARG C 1 328 ? 151.830 165.552 108.421 1.00 69.77  ? 328 ARG C C   1 
ATOM   11730 O O   . ARG C 1 328 ? 152.597 165.817 109.329 1.00 84.99  ? 328 ARG C O   1 
ATOM   11731 C CB  . ARG C 1 328 ? 149.560 166.325 109.162 1.00 63.15  ? 328 ARG C CB  1 
ATOM   11732 C CG  . ARG C 1 328 ? 148.515 167.441 109.125 1.00 63.99  ? 328 ARG C CG  1 
ATOM   11733 C CD  . ARG C 1 328 ? 147.666 167.442 110.400 1.00 71.03  ? 328 ARG C CD  1 
ATOM   11734 N NE  . ARG C 1 328 ? 148.405 167.982 111.554 1.00 68.65  ? 328 ARG C NE  1 
ATOM   11735 C CZ  . ARG C 1 328 ? 148.370 169.215 112.003 1.00 70.82  ? 328 ARG C CZ  1 
ATOM   11736 N NH1 . ARG C 1 328 ? 149.166 169.573 112.957 1.00 72.88  ? 328 ARG C NH1 1 
ATOM   11737 N NH2 . ARG C 1 328 ? 147.577 170.113 111.510 1.00 70.40  ? 328 ARG C NH2 1 
ATOM   11738 N N   . LYS C 1 329 ? 151.975 164.461 107.671 1.00 59.74  ? 329 LYS C N   1 
ATOM   11739 C CA  . LYS C 1 329 ? 153.058 163.474 107.760 1.00 54.97  ? 329 LYS C CA  1 
ATOM   11740 C C   . LYS C 1 329 ? 153.917 163.528 106.506 1.00 61.48  ? 329 LYS C C   1 
ATOM   11741 O O   . LYS C 1 329 ? 153.387 163.459 105.405 1.00 75.22  ? 329 LYS C O   1 
ATOM   11742 C CB  . LYS C 1 329 ? 152.422 162.094 107.926 1.00 59.57  ? 329 LYS C CB  1 
ATOM   11743 C CG  . LYS C 1 329 ? 153.404 160.920 107.962 1.00 57.47  ? 329 LYS C CG  1 
ATOM   11744 C CD  . LYS C 1 329 ? 152.616 159.611 107.898 1.00 59.91  ? 329 LYS C CD  1 
ATOM   11745 C CE  . LYS C 1 329 ? 153.545 158.407 107.992 1.00 66.45  ? 329 LYS C CE  1 
ATOM   11746 N NZ  . LYS C 1 329 ? 152.803 157.137 107.815 1.00 64.85  ? 329 LYS C NZ  1 
ATOM   11747 N N   . PHE C 1 330 ? 155.232 163.589 106.657 1.00 65.44  ? 330 PHE C N   1 
ATOM   11748 C CA  . PHE C 1 330 ? 156.189 163.542 105.554 1.00 66.30  ? 330 PHE C CA  1 
ATOM   11749 C C   . PHE C 1 330 ? 157.164 162.385 105.766 1.00 71.80  ? 330 PHE C C   1 
ATOM   11750 O O   . PHE C 1 330 ? 157.943 162.428 106.712 1.00 76.23  ? 330 PHE C O   1 
ATOM   11751 C CB  . PHE C 1 330 ? 156.930 164.885 105.474 1.00 63.24  ? 330 PHE C CB  1 
ATOM   11752 C CG  . PHE C 1 330 ? 156.023 166.094 105.416 1.00 69.94  ? 330 PHE C CG  1 
ATOM   11753 C CD1 . PHE C 1 330 ? 155.567 166.691 106.606 1.00 71.60  ? 330 PHE C CD1 1 
ATOM   11754 C CD2 . PHE C 1 330 ? 155.613 166.615 104.176 1.00 68.42  ? 330 PHE C CD2 1 
ATOM   11755 C CE1 . PHE C 1 330 ? 154.692 167.781 106.559 1.00 70.83  ? 330 PHE C CE1 1 
ATOM   11756 C CE2 . PHE C 1 330 ? 154.757 167.723 104.127 1.00 69.24  ? 330 PHE C CE2 1 
ATOM   11757 C CZ  . PHE C 1 330 ? 154.290 168.297 105.318 1.00 75.42  ? 330 PHE C CZ  1 
ATOM   11758 N N   . THR C 1 331 ? 157.166 161.361 104.917 1.00 77.85  ? 331 THR C N   1 
ATOM   11759 C CA  . THR C 1 331 ? 158.183 160.300 104.990 1.00 73.69  ? 331 THR C CA  1 
ATOM   11760 C C   . THR C 1 331 ? 159.557 160.872 104.649 1.00 70.69  ? 331 THR C C   1 
ATOM   11761 O O   . THR C 1 331 ? 159.763 161.391 103.556 1.00 75.83  ? 331 THR C O   1 
ATOM   11762 C CB  . THR C 1 331 ? 157.862 159.123 104.064 1.00 78.69  ? 331 THR C CB  1 
ATOM   11763 O OG1 . THR C 1 331 ? 156.605 158.571 104.375 1.00 80.96  ? 331 THR C OG1 1 
ATOM   11764 C CG2 . THR C 1 331 ? 158.873 157.991 104.221 1.00 75.64  ? 331 THR C CG2 1 
ATOM   11765 N N   . GLU C 1 332 ? 160.511 160.788 105.572 1.00 73.33  ? 332 GLU C N   1 
ATOM   11766 C CA  . GLU C 1 332 ? 161.881 161.263 105.396 1.00 75.72  ? 332 GLU C CA  1 
ATOM   11767 C C   . GLU C 1 332 ? 162.731 160.240 104.637 1.00 80.85  ? 332 GLU C C   1 
ATOM   11768 O O   . GLU C 1 332 ? 163.372 160.570 103.639 1.00 79.33  ? 332 GLU C O   1 
ATOM   11769 C CB  . GLU C 1 332 ? 162.486 161.577 106.771 1.00 72.89  ? 332 GLU C CB  1 
ATOM   11770 C CG  . GLU C 1 332 ? 163.908 162.123 106.632 1.00 80.28  ? 332 GLU C CG  1 
ATOM   11771 C CD  . GLU C 1 332 ? 164.574 162.417 107.974 1.00 88.18  ? 332 GLU C CD  1 
ATOM   11772 O OE1 . GLU C 1 332 ? 163.903 162.918 108.899 1.00 89.63  ? 332 GLU C OE1 1 
ATOM   11773 O OE2 . GLU C 1 332 ? 165.795 162.187 108.101 1.00 86.34  ? 332 GLU C OE2 1 
ATOM   11774 N N   . TRP C 1 333 ? 162.717 158.988 105.095 1.00 75.72  ? 333 TRP C N   1 
ATOM   11775 C CA  . TRP C 1 333 ? 163.286 157.843 104.390 1.00 69.12  ? 333 TRP C CA  1 
ATOM   11776 C C   . TRP C 1 333 ? 162.565 156.555 104.771 1.00 69.11  ? 333 TRP C C   1 
ATOM   11777 O O   . TRP C 1 333 ? 161.919 156.454 105.809 1.00 76.17  ? 333 TRP C O   1 
ATOM   11778 C CB  . TRP C 1 333 ? 164.806 157.748 104.598 1.00 68.11  ? 333 TRP C CB  1 
ATOM   11779 C CG  . TRP C 1 333 ? 165.340 157.559 105.986 1.00 68.38  ? 333 TRP C CG  1 
ATOM   11780 C CD1 . TRP C 1 333 ? 165.893 158.535 106.735 1.00 68.47  ? 333 TRP C CD1 1 
ATOM   11781 C CD2 . TRP C 1 333 ? 165.457 156.339 106.784 1.00 74.00  ? 333 TRP C CD2 1 
ATOM   11782 N NE1 . TRP C 1 333 ? 166.340 158.012 107.927 1.00 69.03  ? 333 TRP C NE1 1 
ATOM   11783 C CE2 . TRP C 1 333 ? 166.115 156.659 108.003 1.00 69.90  ? 333 TRP C CE2 1 
ATOM   11784 C CE3 . TRP C 1 333 ? 165.103 154.986 106.601 1.00 77.88  ? 333 TRP C CE3 1 
ATOM   11785 C CZ2 . TRP C 1 333 ? 166.400 155.699 108.979 1.00 66.92  ? 333 TRP C CZ2 1 
ATOM   11786 C CZ3 . TRP C 1 333 ? 165.361 154.019 107.588 1.00 69.62  ? 333 TRP C CZ3 1 
ATOM   11787 C CH2 . TRP C 1 333 ? 166.017 154.369 108.772 1.00 68.74  ? 333 TRP C CH2 1 
ATOM   11788 N N   . CYS C 1 334 ? 162.675 155.555 103.912 1.00 77.58  ? 334 CYS C N   1 
ATOM   11789 C CA  . CYS C 1 334 ? 162.162 154.212 104.124 1.00 77.52  ? 334 CYS C CA  1 
ATOM   11790 C C   . CYS C 1 334 ? 163.216 153.196 103.674 1.00 82.08  ? 334 CYS C C   1 
ATOM   11791 O O   . CYS C 1 334 ? 163.808 153.346 102.600 1.00 86.72  ? 334 CYS C O   1 
ATOM   11792 C CB  . CYS C 1 334 ? 160.841 154.083 103.364 1.00 82.34  ? 334 CYS C CB  1 
ATOM   11793 S SG  . CYS C 1 334 ? 160.168 152.416 103.538 1.00 93.31  ? 334 CYS C SG  1 
ATOM   11794 N N   . TYR C 1 335 ? 163.471 152.179 104.491 1.00 73.79  ? 335 TYR C N   1 
ATOM   11795 C CA  . TYR C 1 335 ? 164.471 151.150 104.223 1.00 75.48  ? 335 TYR C CA  1 
ATOM   11796 C C   . TYR C 1 335 ? 164.066 149.836 104.885 1.00 74.68  ? 335 TYR C C   1 
ATOM   11797 O O   . TYR C 1 335 ? 164.051 149.717 106.109 1.00 77.59  ? 335 TYR C O   1 
ATOM   11798 C CB  . TYR C 1 335 ? 165.851 151.627 104.685 1.00 76.01  ? 335 TYR C CB  1 
ATOM   11799 C CG  . TYR C 1 335 ? 166.987 150.729 104.255 1.00 77.75  ? 335 TYR C CG  1 
ATOM   11800 C CD1 . TYR C 1 335 ? 167.576 150.895 102.989 1.00 78.66  ? 335 TYR C CD1 1 
ATOM   11801 C CD2 . TYR C 1 335 ? 167.444 149.714 105.106 1.00 72.59  ? 335 TYR C CD2 1 
ATOM   11802 C CE1 . TYR C 1 335 ? 168.593 150.027 102.568 1.00 76.74  ? 335 TYR C CE1 1 
ATOM   11803 C CE2 . TYR C 1 335 ? 168.471 148.850 104.691 1.00 72.75  ? 335 TYR C CE2 1 
ATOM   11804 C CZ  . TYR C 1 335 ? 169.033 148.991 103.412 1.00 77.48  ? 335 TYR C CZ  1 
ATOM   11805 O OH  . TYR C 1 335 ? 169.982 148.118 102.998 1.00 79.17  ? 335 TYR C OH  1 
ATOM   11806 N N   . GLY C 1 336 ? 163.703 148.843 104.086 1.00 73.00  ? 336 GLY C N   1 
ATOM   11807 C CA  . GLY C 1 336 ? 163.190 147.581 104.581 1.00 74.84  ? 336 GLY C CA  1 
ATOM   11808 C C   . GLY C 1 336 ? 161.909 147.807 105.388 1.00 77.83  ? 336 GLY C C   1 
ATOM   11809 O O   . GLY C 1 336 ? 161.061 148.586 104.957 1.00 79.79  ? 336 GLY C O   1 
ATOM   11810 N N   . PRO C 1 337 ? 161.743 147.179 106.560 1.00 77.11  ? 337 PRO C N   1 
ATOM   11811 C CA  . PRO C 1 337 ? 160.561 147.325 107.395 1.00 77.58  ? 337 PRO C CA  1 
ATOM   11812 C C   . PRO C 1 337 ? 160.492 148.676 108.119 1.00 81.45  ? 337 PRO C C   1 
ATOM   11813 O O   . PRO C 1 337 ? 159.541 148.904 108.864 1.00 80.76  ? 337 PRO C O   1 
ATOM   11814 C CB  . PRO C 1 337 ? 160.641 146.153 108.371 1.00 69.71  ? 337 PRO C CB  1 
ATOM   11815 C CG  . PRO C 1 337 ? 162.135 145.984 108.564 1.00 73.21  ? 337 PRO C CG  1 
ATOM   11816 C CD  . PRO C 1 337 ? 162.684 146.280 107.180 1.00 72.39  ? 337 PRO C CD  1 
ATOM   11817 N N   . VAL C 1 338 ? 161.479 149.558 107.945 1.00 83.39  ? 338 VAL C N   1 
ATOM   11818 C CA  . VAL C 1 338 ? 161.632 150.792 108.718 1.00 80.52  ? 338 VAL C CA  1 
ATOM   11819 C C   . VAL C 1 338 ? 161.205 152.000 107.900 1.00 80.90  ? 338 VAL C C   1 
ATOM   11820 O O   . VAL C 1 338 ? 161.755 152.253 106.831 1.00 82.96  ? 338 VAL C O   1 
ATOM   11821 C CB  . VAL C 1 338 ? 163.078 150.978 109.208 1.00 74.15  ? 338 VAL C CB  1 
ATOM   11822 C CG1 . VAL C 1 338 ? 163.148 152.115 110.230 1.00 74.68  ? 338 VAL C CG1 1 
ATOM   11823 C CG2 . VAL C 1 338 ? 163.626 149.689 109.822 1.00 71.64  ? 338 VAL C CG2 1 
ATOM   11824 N N   . ARG C 1 339 ? 160.262 152.786 108.424 1.00 81.97  ? 339 ARG C N   1 
ATOM   11825 C CA  . ARG C 1 339 ? 159.897 154.107 107.907 1.00 82.30  ? 339 ARG C CA  1 
ATOM   11826 C C   . ARG C 1 339 ? 160.269 155.171 108.921 1.00 81.74  ? 339 ARG C C   1 
ATOM   11827 O O   . ARG C 1 339 ? 159.905 155.050 110.083 1.00 90.00  ? 339 ARG C O   1 
ATOM   11828 C CB  . ARG C 1 339 ? 158.395 154.192 107.620 1.00 84.63  ? 339 ARG C CB  1 
ATOM   11829 C CG  . ARG C 1 339 ? 157.918 153.164 106.590 1.00 88.26  ? 339 ARG C CG  1 
ATOM   11830 C CD  . ARG C 1 339 ? 156.476 153.435 106.157 1.00 86.21  ? 339 ARG C CD  1 
ATOM   11831 N NE  . ARG C 1 339 ? 156.379 154.640 105.307 1.00 90.05  ? 339 ARG C NE  1 
ATOM   11832 C CZ  . ARG C 1 339 ? 156.302 154.679 103.989 1.00 93.03  ? 339 ARG C CZ  1 
ATOM   11833 N NH1 . ARG C 1 339 ? 156.222 155.817 103.366 1.00 91.10  ? 339 ARG C NH1 1 
ATOM   11834 N NH2 . ARG C 1 339 ? 156.302 153.605 103.256 1.00 93.48  ? 339 ARG C NH2 1 
ATOM   11835 N N   . VAL C 1 340 ? 160.922 156.241 108.493 1.00 68.47  ? 340 VAL C N   1 
ATOM   11836 C CA  . VAL C 1 340 ? 161.122 157.441 109.310 1.00 66.56  ? 340 VAL C CA  1 
ATOM   11837 C C   . VAL C 1 340 ? 160.267 158.566 108.751 1.00 75.70  ? 340 VAL C C   1 
ATOM   11838 O O   . VAL C 1 340 ? 160.353 158.874 107.568 1.00 85.22  ? 340 VAL C O   1 
ATOM   11839 C CB  . VAL C 1 340 ? 162.605 157.806 109.393 1.00 64.03  ? 340 VAL C CB  1 
ATOM   11840 C CG1 . VAL C 1 340 ? 162.820 159.065 110.229 1.00 70.34  ? 340 VAL C CG1 1 
ATOM   11841 C CG2 . VAL C 1 340 ? 163.356 156.647 110.045 1.00 73.70  ? 340 VAL C CG2 1 
ATOM   11842 N N   . SER C 1 341 ? 159.423 159.177 109.580 1.00 70.89  ? 341 SER C N   1 
ATOM   11843 C CA  . SER C 1 341 ? 158.464 160.204 109.170 1.00 65.48  ? 341 SER C CA  1 
ATOM   11844 C C   . SER C 1 341 ? 158.535 161.422 110.071 1.00 67.10  ? 341 SER C C   1 
ATOM   11845 O O   . SER C 1 341 ? 158.592 161.291 111.286 1.00 82.65  ? 341 SER C O   1 
ATOM   11846 C CB  . SER C 1 341 ? 157.034 159.675 109.206 1.00 68.13  ? 341 SER C CB  1 
ATOM   11847 O OG  . SER C 1 341 ? 156.883 158.521 108.411 1.00 78.86  ? 341 SER C OG  1 
ATOM   11848 N N   . LEU C 1 342 ? 158.464 162.611 109.491 1.00 61.67  ? 342 LEU C N   1 
ATOM   11849 C CA  . LEU C 1 342 ? 158.224 163.861 110.198 1.00 58.61  ? 342 LEU C CA  1 
ATOM   11850 C C   . LEU C 1 342 ? 156.720 164.099 110.306 1.00 59.97  ? 342 LEU C C   1 
ATOM   11851 O O   . LEU C 1 342 ? 156.038 164.127 109.292 1.00 71.36  ? 342 LEU C O   1 
ATOM   11852 C CB  . LEU C 1 342 ? 158.873 165.001 109.403 1.00 64.04  ? 342 LEU C CB  1 
ATOM   11853 C CG  . LEU C 1 342 ? 160.398 164.943 109.297 1.00 60.17  ? 342 LEU C CG  1 
ATOM   11854 C CD1 . LEU C 1 342 ? 160.877 166.112 108.448 1.00 68.02  ? 342 LEU C CD1 1 
ATOM   11855 C CD2 . LEU C 1 342 ? 161.068 165.031 110.661 1.00 60.14  ? 342 LEU C CD2 1 
ATOM   11856 N N   . TYR C 1 343 ? 156.193 164.291 111.507 1.00 57.47  ? 343 TYR C N   1 
ATOM   11857 C CA  . TYR C 1 343 ? 154.802 164.662 111.749 1.00 58.15  ? 343 TYR C CA  1 
ATOM   11858 C C   . TYR C 1 343 ? 154.696 166.120 112.199 1.00 67.60  ? 343 TYR C C   1 
ATOM   11859 O O   . TYR C 1 343 ? 155.434 166.560 113.069 1.00 75.03  ? 343 TYR C O   1 
ATOM   11860 C CB  . TYR C 1 343 ? 154.203 163.737 112.797 1.00 56.61  ? 343 TYR C CB  1 
ATOM   11861 C CG  . TYR C 1 343 ? 153.906 162.328 112.332 1.00 52.20  ? 343 TYR C CG  1 
ATOM   11862 C CD1 . TYR C 1 343 ? 154.887 161.328 112.421 1.00 55.58  ? 343 TYR C CD1 1 
ATOM   11863 C CD2 . TYR C 1 343 ? 152.615 162.003 111.893 1.00 56.32  ? 343 TYR C CD2 1 
ATOM   11864 C CE1 . TYR C 1 343 ? 154.558 159.997 112.107 1.00 61.52  ? 343 TYR C CE1 1 
ATOM   11865 C CE2 . TYR C 1 343 ? 152.283 160.671 111.604 1.00 59.31  ? 343 TYR C CE2 1 
ATOM   11866 C CZ  . TYR C 1 343 ? 153.250 159.660 111.736 1.00 61.95  ? 343 TYR C CZ  1 
ATOM   11867 O OH  . TYR C 1 343 ? 152.934 158.363 111.500 1.00 62.91  ? 343 TYR C OH  1 
ATOM   11868 N N   . ASP C 1 344 ? 153.776 166.879 111.623 1.00 71.01  ? 344 ASP C N   1 
ATOM   11869 C CA  . ASP C 1 344 ? 153.505 168.285 111.912 1.00 69.50  ? 344 ASP C CA  1 
ATOM   11870 C C   . ASP C 1 344 ? 152.722 168.472 113.227 1.00 72.06  ? 344 ASP C C   1 
ATOM   11871 O O   . ASP C 1 344 ? 151.583 168.017 113.346 1.00 78.52  ? 344 ASP C O   1 
ATOM   11872 C CB  . ASP C 1 344 ? 152.731 168.819 110.705 1.00 72.25  ? 344 ASP C CB  1 
ATOM   11873 C CG  . ASP C 1 344 ? 152.325 170.283 110.790 1.00 71.87  ? 344 ASP C CG  1 
ATOM   11874 O OD1 . ASP C 1 344 ? 152.702 170.963 111.766 1.00 76.52  ? 344 ASP C OD1 1 
ATOM   11875 O OD2 . ASP C 1 344 ? 151.651 170.738 109.843 1.00 63.91  ? 344 ASP C OD2 1 
ATOM   11876 N N   . LEU C 1 345 ? 153.310 169.154 114.216 1.00 66.69  ? 345 LEU C N   1 
ATOM   11877 C CA  . LEU C 1 345 ? 152.743 169.318 115.555 1.00 60.02  ? 345 LEU C CA  1 
ATOM   11878 C C   . LEU C 1 345 ? 151.949 170.618 115.782 1.00 60.34  ? 345 LEU C C   1 
ATOM   11879 O O   . LEU C 1 345 ? 151.638 170.929 116.929 1.00 70.84  ? 345 LEU C O   1 
ATOM   11880 C CB  . LEU C 1 345 ? 153.845 169.165 116.616 1.00 61.42  ? 345 LEU C CB  1 
ATOM   11881 C CG  . LEU C 1 345 ? 154.562 167.814 116.691 1.00 57.89  ? 345 LEU C CG  1 
ATOM   11882 C CD1 . LEU C 1 345 ? 155.322 167.770 118.011 1.00 68.00  ? 345 LEU C CD1 1 
ATOM   11883 C CD2 . LEU C 1 345 ? 153.606 166.628 116.667 1.00 65.68  ? 345 LEU C CD2 1 
ATOM   11884 N N   . SER C 1 346 ? 151.596 171.378 114.743 1.00 65.68  ? 346 SER C N   1 
ATOM   11885 C CA  . SER C 1 346 ? 151.070 172.753 114.858 1.00 73.41  ? 346 SER C CA  1 
ATOM   11886 C C   . SER C 1 346 ? 149.958 172.965 115.903 1.00 79.54  ? 346 SER C C   1 
ATOM   11887 O O   . SER C 1 346 ? 150.147 173.724 116.852 1.00 84.43  ? 346 SER C O   1 
ATOM   11888 C CB  . SER C 1 346 ? 150.624 173.265 113.487 1.00 73.10  ? 346 SER C CB  1 
ATOM   11889 O OG  . SER C 1 346 ? 149.567 172.489 112.942 1.00 71.95  ? 346 SER C OG  1 
ATOM   11890 N N   . SER C 1 347 ? 148.821 172.279 115.780 1.00 67.78  ? 347 SER C N   1 
ATOM   11891 C CA  . SER C 1 347 ? 147.720 172.285 116.748 1.00 60.97  ? 347 SER C CA  1 
ATOM   11892 C C   . SER C 1 347 ? 147.884 171.288 117.898 1.00 67.38  ? 347 SER C C   1 
ATOM   11893 O O   . SER C 1 347 ? 146.983 171.176 118.726 1.00 77.64  ? 347 SER C O   1 
ATOM   11894 C CB  . SER C 1 347 ? 146.410 171.955 116.023 1.00 67.47  ? 347 SER C CB  1 
ATOM   11895 O OG  . SER C 1 347 ? 146.216 172.761 114.877 1.00 70.30  ? 347 SER C OG  1 
ATOM   11896 N N   . VAL C 1 348 ? 148.955 170.492 117.916 1.00 67.71  ? 348 VAL C N   1 
ATOM   11897 C CA  . VAL C 1 348 ? 149.056 169.242 118.684 1.00 61.35  ? 348 VAL C CA  1 
ATOM   11898 C C   . VAL C 1 348 ? 149.860 169.368 119.974 1.00 59.48  ? 348 VAL C C   1 
ATOM   11899 O O   . VAL C 1 348 ? 149.428 168.849 120.996 1.00 63.30  ? 348 VAL C O   1 
ATOM   11900 C CB  . VAL C 1 348 ? 149.581 168.096 117.801 1.00 61.56  ? 348 VAL C CB  1 
ATOM   11901 C CG1 . VAL C 1 348 ? 149.699 166.772 118.551 1.00 59.46  ? 348 VAL C CG1 1 
ATOM   11902 C CG2 . VAL C 1 348 ? 148.666 167.837 116.601 1.00 61.42  ? 348 VAL C CG2 1 
ATOM   11903 N N   . ASP C 1 349 ? 151.016 170.021 119.916 1.00 74.71  ? 349 ASP C N   1 
ATOM   11904 C CA  . ASP C 1 349 ? 151.903 170.144 121.066 1.00 77.73  ? 349 ASP C CA  1 
ATOM   11905 C C   . ASP C 1 349 ? 151.274 171.042 122.141 1.00 88.05  ? 349 ASP C C   1 
ATOM   11906 O O   . ASP C 1 349 ? 150.767 172.128 121.863 1.00 88.56  ? 349 ASP C O   1 
ATOM   11907 C CB  . ASP C 1 349 ? 153.278 170.649 120.614 1.00 73.42  ? 349 ASP C CB  1 
ATOM   11908 C CG  . ASP C 1 349 ? 154.321 170.683 121.740 1.00 86.49  ? 349 ASP C CG  1 
ATOM   11909 O OD1 . ASP C 1 349 ? 154.114 170.007 122.777 1.00 86.69  ? 349 ASP C OD1 1 
ATOM   11910 O OD2 . ASP C 1 349 ? 155.328 171.400 121.568 1.00 90.94  ? 349 ASP C OD2 1 
ATOM   11911 N N   . SER C 1 350 ? 151.352 170.600 123.391 1.00 85.64  ? 350 SER C N   1 
ATOM   11912 C CA  . SER C 1 350 ? 150.791 171.232 124.582 1.00 78.85  ? 350 SER C CA  1 
ATOM   11913 C C   . SER C 1 350 ? 151.442 172.562 124.970 1.00 74.93  ? 350 SER C C   1 
ATOM   11914 O O   . SER C 1 350 ? 150.980 173.230 125.896 1.00 78.80  ? 350 SER C O   1 
ATOM   11915 C CB  . SER C 1 350 ? 150.870 170.221 125.717 1.00 82.47  ? 350 SER C CB  1 
ATOM   11916 O OG  . SER C 1 350 ? 152.183 169.731 125.829 1.00 86.56  ? 350 SER C OG  1 
ATOM   11917 N N   . TRP C 1 351 ? 152.483 172.979 124.255 1.00 82.44  ? 351 TRP C N   1 
ATOM   11918 C CA  . TRP C 1 351 ? 153.024 174.335 124.266 1.00 85.36  ? 351 TRP C CA  1 
ATOM   11919 C C   . TRP C 1 351 ? 151.974 175.387 123.874 1.00 89.91  ? 351 TRP C C   1 
ATOM   11920 O O   . TRP C 1 351 ? 151.938 176.473 124.447 1.00 91.59  ? 351 TRP C O   1 
ATOM   11921 C CB  . TRP C 1 351 ? 154.224 174.343 123.312 1.00 84.69  ? 351 TRP C CB  1 
ATOM   11922 C CG  . TRP C 1 351 ? 154.881 175.660 123.071 1.00 89.69  ? 351 TRP C CG  1 
ATOM   11923 C CD1 . TRP C 1 351 ? 155.923 176.152 123.775 1.00 91.81  ? 351 TRP C CD1 1 
ATOM   11924 C CD2 . TRP C 1 351 ? 154.561 176.669 122.068 1.00 93.15  ? 351 TRP C CD2 1 
ATOM   11925 N NE1 . TRP C 1 351 ? 156.267 177.393 123.286 1.00 89.85  ? 351 TRP C NE1 1 
ATOM   11926 C CE2 . TRP C 1 351 ? 155.462 177.764 122.231 1.00 90.81  ? 351 TRP C CE2 1 
ATOM   11927 C CE3 . TRP C 1 351 ? 153.616 176.770 121.026 1.00 92.06  ? 351 TRP C CE3 1 
ATOM   11928 C CZ2 . TRP C 1 351 ? 155.416 178.902 121.418 1.00 86.56  ? 351 TRP C CZ2 1 
ATOM   11929 C CZ3 . TRP C 1 351 ? 153.556 177.914 120.207 1.00 90.74  ? 351 TRP C CZ3 1 
ATOM   11930 C CH2 . TRP C 1 351 ? 154.450 178.978 120.403 1.00 87.77  ? 351 TRP C CH2 1 
ATOM   11931 N N   . GLU C 1 352 ? 151.076 175.057 122.944 1.00 95.32  ? 352 GLU C N   1 
ATOM   11932 C CA  . GLU C 1 352 ? 149.918 175.883 122.588 1.00 95.96  ? 352 GLU C CA  1 
ATOM   11933 C C   . GLU C 1 352 ? 148.751 175.688 123.576 1.00 97.84  ? 352 GLU C C   1 
ATOM   11934 O O   . GLU C 1 352 ? 148.378 174.558 123.911 1.00 99.88  ? 352 GLU C O   1 
ATOM   11935 C CB  . GLU C 1 352 ? 149.518 175.586 121.129 1.00 91.70  ? 352 GLU C CB  1 
ATOM   11936 N N   . LYS C 1 353 ? 148.123 176.787 124.007 1.00 89.28  ? 353 LYS C N   1 
ATOM   11937 C CA  . LYS C 1 353 ? 146.883 176.770 124.800 1.00 89.62  ? 353 LYS C CA  1 
ATOM   11938 C C   . LYS C 1 353 ? 145.713 176.263 123.960 1.00 93.23  ? 353 LYS C C   1 
ATOM   11939 O O   . LYS C 1 353 ? 145.596 176.648 122.799 1.00 91.67  ? 353 LYS C O   1 
ATOM   11940 C CB  . LYS C 1 353 ? 146.585 178.180 125.336 1.00 91.53  ? 353 LYS C CB  1 
ATOM   11941 C CG  . LYS C 1 353 ? 147.655 178.692 126.309 1.00 94.52  ? 353 LYS C CG  1 
ATOM   11942 C CD  . LYS C 1 353 ? 147.325 180.110 126.783 1.00 95.05  ? 353 LYS C CD  1 
ATOM   11943 C CE  . LYS C 1 353 ? 148.424 180.625 127.712 1.00 93.52  ? 353 LYS C CE  1 
ATOM   11944 N NZ  . LYS C 1 353 ? 148.164 182.013 128.153 1.00 95.07  ? 353 LYS C NZ  1 
ATOM   11945 N N   . ASN C 1 354 ? 144.823 175.443 124.523 1.00 81.99  ? 354 ASN C N   1 
ATOM   11946 C CA  . ASN C 1 354 ? 143.725 174.805 123.781 1.00 78.89  ? 354 ASN C CA  1 
ATOM   11947 C C   . ASN C 1 354 ? 144.222 173.948 122.599 1.00 79.07  ? 354 ASN C C   1 
ATOM   11948 O O   . ASN C 1 354 ? 143.722 174.036 121.480 1.00 85.90  ? 354 ASN C O   1 
ATOM   11949 C CB  . ASN C 1 354 ? 142.661 175.860 123.420 1.00 86.04  ? 354 ASN C CB  1 
ATOM   11950 C CG  . ASN C 1 354 ? 141.372 175.256 122.900 1.00 90.81  ? 354 ASN C CG  1 
ATOM   11951 O OD1 . ASN C 1 354 ? 140.908 174.234 123.377 1.00 88.85  ? 354 ASN C OD1 1 
ATOM   11952 N ND2 . ASN C 1 354 ? 140.742 175.878 121.935 1.00 84.37  ? 354 ASN C ND2 1 
ATOM   11953 N N   . SER C 1 355 ? 145.284 173.172 122.801 1.00 69.85  ? 355 SER C N   1 
ATOM   11954 C CA  . SER C 1 355 ? 145.833 172.213 121.836 1.00 59.36  ? 355 SER C CA  1 
ATOM   11955 C C   . SER C 1 355 ? 145.121 170.860 121.889 1.00 62.73  ? 355 SER C C   1 
ATOM   11956 O O   . SER C 1 355 ? 144.381 170.562 122.817 1.00 78.13  ? 355 SER C O   1 
ATOM   11957 C CB  . SER C 1 355 ? 147.329 172.036 122.088 1.00 59.88  ? 355 SER C CB  1 
ATOM   11958 O OG  . SER C 1 355 ? 147.587 171.890 123.465 1.00 60.43  ? 355 SER C OG  1 
ATOM   11959 N N   . VAL C 1 356 ? 145.351 170.014 120.890 1.00 46.41  ? 356 VAL C N   1 
ATOM   11960 C CA  . VAL C 1 356 ? 144.730 168.681 120.747 1.00 39.39  ? 356 VAL C CA  1 
ATOM   11961 C C   . VAL C 1 356 ? 144.984 167.773 121.950 1.00 46.49  ? 356 VAL C C   1 
ATOM   11962 O O   . VAL C 1 356 ? 144.104 167.016 122.334 1.00 70.73  ? 356 VAL C O   1 
ATOM   11963 C CB  . VAL C 1 356 ? 145.214 168.011 119.451 1.00 49.47  ? 356 VAL C CB  1 
ATOM   11964 C CG1 . VAL C 1 356 ? 144.927 166.522 119.320 1.00 52.94  ? 356 VAL C CG1 1 
ATOM   11965 C CG2 . VAL C 1 356 ? 144.601 168.696 118.231 1.00 52.81  ? 356 VAL C CG2 1 
ATOM   11966 N N   . LEU C 1 357 ? 146.167 167.829 122.556 1.00 60.77  ? 357 LEU C N   1 
ATOM   11967 C CA  . LEU C 1 357 ? 146.465 167.039 123.747 1.00 56.43  ? 357 LEU C CA  1 
ATOM   11968 C C   . LEU C 1 357 ? 145.645 167.500 124.959 1.00 62.16  ? 357 LEU C C   1 
ATOM   11969 O O   . LEU C 1 357 ? 145.063 166.674 125.653 1.00 67.67  ? 357 LEU C O   1 
ATOM   11970 C CB  . LEU C 1 357 ? 147.974 167.101 124.021 1.00 57.65  ? 357 LEU C CB  1 
ATOM   11971 C CG  . LEU C 1 357 ? 148.838 166.311 123.030 1.00 64.38  ? 357 LEU C CG  1 
ATOM   11972 C CD1 . LEU C 1 357 ? 150.304 166.514 123.393 1.00 67.91  ? 357 LEU C CD1 1 
ATOM   11973 C CD2 . LEU C 1 357 ? 148.520 164.821 123.087 1.00 61.92  ? 357 LEU C CD2 1 
ATOM   11974 N N   . GLU C 1 358 ? 145.531 168.810 125.189 1.00 74.43  ? 358 GLU C N   1 
ATOM   11975 C CA  . GLU C 1 358 ? 144.670 169.376 126.229 1.00 66.70  ? 358 GLU C CA  1 
ATOM   11976 C C   . GLU C 1 358 ? 143.196 169.011 126.017 1.00 67.83  ? 358 GLU C C   1 
ATOM   11977 O O   . GLU C 1 358 ? 142.506 168.614 126.948 1.00 83.17  ? 358 GLU C O   1 
ATOM   11978 C CB  . GLU C 1 358 ? 144.887 170.896 126.286 1.00 69.92  ? 358 GLU C CB  1 
ATOM   11979 C CG  . GLU C 1 358 ? 143.895 171.614 127.205 1.00 82.75  ? 358 GLU C CG  1 
ATOM   11980 C CD  . GLU C 1 358 ? 144.430 172.946 127.740 1.00 86.70  ? 358 GLU C CD  1 
ATOM   11981 O OE1 . GLU C 1 358 ? 144.832 173.811 126.933 1.00 86.01  ? 358 GLU C OE1 1 
ATOM   11982 O OE2 . GLU C 1 358 ? 144.433 173.120 128.980 1.00 85.48  ? 358 GLU C OE2 1 
ATOM   11983 N N   . ILE C 1 359 ? 142.721 169.065 124.781 1.00 59.62  ? 359 ILE C N   1 
ATOM   11984 C CA  . ILE C 1 359 ? 141.366 168.693 124.369 1.00 55.03  ? 359 ILE C CA  1 
ATOM   11985 C C   . ILE C 1 359 ? 141.050 167.226 124.659 1.00 61.96  ? 359 ILE C C   1 
ATOM   11986 O O   . ILE C 1 359 ? 140.032 166.954 125.286 1.00 84.17  ? 359 ILE C O   1 
ATOM   11987 C CB  . ILE C 1 359 ? 141.122 169.051 122.890 1.00 49.39  ? 359 ILE C CB  1 
ATOM   11988 C CG1 . ILE C 1 359 ? 141.012 170.578 122.740 1.00 56.90  ? 359 ILE C CG1 1 
ATOM   11989 C CG2 . ILE C 1 359 ? 139.847 168.394 122.352 1.00 58.96  ? 359 ILE C CG2 1 
ATOM   11990 C CD1 . ILE C 1 359 ? 141.070 171.062 121.298 1.00 56.10  ? 359 ILE C CD1 1 
ATOM   11991 N N   . ILE C 1 360 ? 141.883 166.268 124.255 1.00 57.87  ? 360 ILE C N   1 
ATOM   11992 C CA  . ILE C 1 360 ? 141.627 164.842 124.512 1.00 52.91  ? 360 ILE C CA  1 
ATOM   11993 C C   . ILE C 1 360 ? 141.603 164.564 126.014 1.00 65.30  ? 360 ILE C C   1 
ATOM   11994 O O   . ILE C 1 360 ? 140.740 163.832 126.498 1.00 77.56  ? 360 ILE C O   1 
ATOM   11995 C CB  . ILE C 1 360 ? 142.671 163.950 123.814 1.00 59.37  ? 360 ILE C CB  1 
ATOM   11996 C CG1 . ILE C 1 360 ? 142.549 164.069 122.288 1.00 58.80  ? 360 ILE C CG1 1 
ATOM   11997 C CG2 . ILE C 1 360 ? 142.518 162.481 124.234 1.00 59.81  ? 360 ILE C CG2 1 
ATOM   11998 C CD1 . ILE C 1 360 ? 143.804 163.602 121.561 1.00 57.86  ? 360 ILE C CD1 1 
ATOM   11999 N N   . ALA C 1 361 ? 142.540 165.144 126.753 1.00 64.11  ? 361 ALA C N   1 
ATOM   12000 C CA  . ALA C 1 361 ? 142.619 164.946 128.180 1.00 63.38  ? 361 ALA C CA  1 
ATOM   12001 C C   . ALA C 1 361 ? 141.413 165.575 128.901 1.00 64.22  ? 361 ALA C C   1 
ATOM   12002 O O   . ALA C 1 361 ? 140.755 164.890 129.674 1.00 67.29  ? 361 ALA C O   1 
ATOM   12003 C CB  . ALA C 1 361 ? 143.964 165.489 128.647 1.00 68.50  ? 361 ALA C CB  1 
ATOM   12004 N N   . PHE C 1 362 ? 141.090 166.841 128.625 1.00 72.86  ? 362 PHE C N   1 
ATOM   12005 C CA  . PHE C 1 362 ? 140.237 167.649 129.500 1.00 76.37  ? 362 PHE C CA  1 
ATOM   12006 C C   . PHE C 1 362 ? 138.931 168.172 128.889 1.00 76.15  ? 362 PHE C C   1 
ATOM   12007 O O   . PHE C 1 362 ? 138.044 168.550 129.648 1.00 85.79  ? 362 PHE C O   1 
ATOM   12008 C CB  . PHE C 1 362 ? 141.071 168.816 130.045 1.00 72.17  ? 362 PHE C CB  1 
ATOM   12009 C CG  . PHE C 1 362 ? 142.340 168.390 130.755 1.00 74.14  ? 362 PHE C CG  1 
ATOM   12010 C CD1 . PHE C 1 362 ? 142.269 167.731 131.992 1.00 79.87  ? 362 PHE C CD1 1 
ATOM   12011 C CD2 . PHE C 1 362 ? 143.591 168.626 130.170 1.00 74.99  ? 362 PHE C CD2 1 
ATOM   12012 C CE1 . PHE C 1 362 ? 143.443 167.293 132.625 1.00 75.55  ? 362 PHE C CE1 1 
ATOM   12013 C CE2 . PHE C 1 362 ? 144.765 168.181 130.799 1.00 76.61  ? 362 PHE C CE2 1 
ATOM   12014 C CZ  . PHE C 1 362 ? 144.689 167.505 132.020 1.00 75.45  ? 362 PHE C CZ  1 
ATOM   12015 N N   . HIS C 1 363 ? 138.773 168.236 127.565 1.00 68.85  ? 363 HIS C N   1 
ATOM   12016 C CA  . HIS C 1 363 ? 137.567 168.794 126.929 1.00 73.14  ? 363 HIS C CA  1 
ATOM   12017 C C   . HIS C 1 363 ? 136.705 167.755 126.205 1.00 76.67  ? 363 HIS C C   1 
ATOM   12018 O O   . HIS C 1 363 ? 135.528 168.000 125.961 1.00 77.65  ? 363 HIS C O   1 
ATOM   12019 C CB  . HIS C 1 363 ? 137.935 169.908 125.947 1.00 69.08  ? 363 HIS C CB  1 
ATOM   12020 C CG  . HIS C 1 363 ? 138.785 171.033 126.473 1.00 70.97  ? 363 HIS C CG  1 
ATOM   12021 N ND1 . HIS C 1 363 ? 139.386 171.985 125.657 1.00 83.77  ? 363 HIS C ND1 1 
ATOM   12022 C CD2 . HIS C 1 363 ? 139.055 171.344 127.770 1.00 78.05  ? 363 HIS C CD2 1 
ATOM   12023 C CE1 . HIS C 1 363 ? 140.037 172.824 126.475 1.00 79.97  ? 363 HIS C CE1 1 
ATOM   12024 N NE2 . HIS C 1 363 ? 139.854 172.462 127.752 1.00 80.44  ? 363 HIS C NE2 1 
ATOM   12025 N N   . CYS C 1 364 ? 137.268 166.609 125.848 1.00 70.95  ? 364 CYS C N   1 
ATOM   12026 C CA  . CYS C 1 364 ? 136.573 165.501 125.213 1.00 73.86  ? 364 CYS C CA  1 
ATOM   12027 C C   . CYS C 1 364 ? 135.715 164.718 126.225 1.00 80.60  ? 364 CYS C C   1 
ATOM   12028 O O   . CYS C 1 364 ? 136.222 164.325 127.267 1.00 78.85  ? 364 CYS C O   1 
ATOM   12029 C CB  . CYS C 1 364 ? 137.653 164.630 124.568 1.00 67.86  ? 364 CYS C CB  1 
ATOM   12030 S SG  . CYS C 1 364 ? 136.923 163.305 123.587 1.00 80.65  ? 364 CYS C SG  1 
ATOM   12031 N N   . LYS C 1 365 ? 134.432 164.446 125.936 1.00 90.59  ? 365 LYS C N   1 
ATOM   12032 C CA  . LYS C 1 365 ? 133.526 163.652 126.801 1.00 86.95  ? 365 LYS C CA  1 
ATOM   12033 C C   . LYS C 1 365 ? 133.541 162.141 126.542 1.00 88.71  ? 365 LYS C C   1 
ATOM   12034 O O   . LYS C 1 365 ? 132.974 161.376 127.317 1.00 95.80  ? 365 LYS C O   1 
ATOM   12035 C CB  . LYS C 1 365 ? 132.077 164.143 126.631 1.00 92.54  ? 365 LYS C CB  1 
ATOM   12036 C CG  . LYS C 1 365 ? 131.837 165.542 127.193 1.00 96.30  ? 365 LYS C CG  1 
ATOM   12037 C CD  . LYS C 1 365 ? 130.357 165.916 127.131 1.00 96.76  ? 365 LYS C CD  1 
ATOM   12038 C CE  . LYS C 1 365 ? 130.134 167.292 127.746 1.00 94.99  ? 365 LYS C CE  1 
ATOM   12039 N NZ  . LYS C 1 365 ? 128.713 167.674 127.748 1.00 94.43  ? 365 LYS C NZ  1 
ATOM   12040 N N   . SER C 1 366 ? 134.081 161.707 125.409 1.00 78.55  ? 366 SER C N   1 
ATOM   12041 C CA  . SER C 1 366 ? 133.763 160.405 124.798 1.00 80.43  ? 366 SER C CA  1 
ATOM   12042 C C   . SER C 1 366 ? 134.482 159.200 125.425 1.00 79.96  ? 366 SER C C   1 
ATOM   12043 O O   . SER C 1 366 ? 135.573 159.345 125.975 1.00 79.27  ? 366 SER C O   1 
ATOM   12044 C CB  . SER C 1 366 ? 134.063 160.459 123.302 1.00 77.02  ? 366 SER C CB  1 
ATOM   12045 O OG  . SER C 1 366 ? 135.457 160.466 123.084 1.00 78.57  ? 366 SER C OG  1 
ATOM   12046 N N   . PRO C 1 367 ? 133.948 157.971 125.266 1.00 83.72  ? 367 PRO C N   1 
ATOM   12047 C CA  . PRO C 1 367 ? 134.668 156.734 125.580 1.00 79.89  ? 367 PRO C CA  1 
ATOM   12048 C C   . PRO C 1 367 ? 135.988 156.570 124.819 1.00 77.43  ? 367 PRO C C   1 
ATOM   12049 O O   . PRO C 1 367 ? 136.861 155.820 125.237 1.00 77.18  ? 367 PRO C O   1 
ATOM   12050 C CB  . PRO C 1 367 ? 133.716 155.600 125.191 1.00 79.48  ? 367 PRO C CB  1 
ATOM   12051 C CG  . PRO C 1 367 ? 132.338 156.236 125.255 1.00 79.05  ? 367 PRO C CG  1 
ATOM   12052 C CD  . PRO C 1 367 ? 132.600 157.669 124.822 1.00 79.60  ? 367 PRO C CD  1 
ATOM   12053 N N   . ASN C 1 368 ? 136.131 157.236 123.671 1.00 90.09  ? 368 ASN C N   1 
ATOM   12054 C CA  . ASN C 1 368 ? 137.219 157.069 122.704 1.00 84.24  ? 368 ASN C CA  1 
ATOM   12055 C C   . ASN C 1 368 ? 138.560 157.699 123.110 1.00 78.84  ? 368 ASN C C   1 
ATOM   12056 O O   . ASN C 1 368 ? 139.556 157.468 122.434 1.00 85.32  ? 368 ASN C O   1 
ATOM   12057 C CB  . ASN C 1 368 ? 136.753 157.657 121.359 1.00 82.28  ? 368 ASN C CB  1 
ATOM   12058 C CG  . ASN C 1 368 ? 135.752 156.787 120.622 1.00 82.34  ? 368 ASN C CG  1 
ATOM   12059 O OD1 . ASN C 1 368 ? 135.645 155.589 120.820 1.00 84.85  ? 368 ASN C OD1 1 
ATOM   12060 N ND2 . ASN C 1 368 ? 134.981 157.359 119.739 1.00 81.44  ? 368 ASN C ND2 1 
ATOM   12061 N N   . ARG C 1 369 ? 138.638 158.496 124.179 1.00 69.69  ? 369 ARG C N   1 
ATOM   12062 C CA  . ARG C 1 369 ? 139.849 159.260 124.538 1.00 69.13  ? 369 ARG C CA  1 
ATOM   12063 C C   . ARG C 1 369 ? 141.086 158.398 124.687 1.00 71.92  ? 369 ARG C C   1 
ATOM   12064 O O   . ARG C 1 369 ? 142.156 158.774 124.226 1.00 67.72  ? 369 ARG C O   1 
ATOM   12065 C CB  . ARG C 1 369 ? 139.600 160.005 125.847 1.00 71.99  ? 369 ARG C CB  1 
ATOM   12066 C CG  . ARG C 1 369 ? 138.647 161.168 125.626 1.00 70.51  ? 369 ARG C CG  1 
ATOM   12067 C CD  . ARG C 1 369 ? 137.990 161.581 126.930 1.00 76.54  ? 369 ARG C CD  1 
ATOM   12068 N NE  . ARG C 1 369 ? 138.952 162.092 127.914 1.00 70.13  ? 369 ARG C NE  1 
ATOM   12069 C CZ  . ARG C 1 369 ? 139.146 161.609 129.123 1.00 69.22  ? 369 ARG C CZ  1 
ATOM   12070 N NH1 . ARG C 1 369 ? 139.917 162.195 129.978 1.00 76.06  ? 369 ARG C NH1 1 
ATOM   12071 N NH2 . ARG C 1 369 ? 138.591 160.514 129.539 1.00 69.68  ? 369 ARG C NH2 1 
ATOM   12072 N N   . HIS C 1 370 ? 140.950 157.226 125.295 1.00 78.64  ? 370 HIS C N   1 
ATOM   12073 C CA  . HIS C 1 370 ? 142.076 156.329 125.497 1.00 75.64  ? 370 HIS C CA  1 
ATOM   12074 C C   . HIS C 1 370 ? 142.612 155.732 124.189 1.00 74.83  ? 370 HIS C C   1 
ATOM   12075 O O   . HIS C 1 370 ? 143.801 155.460 124.091 1.00 77.47  ? 370 HIS C O   1 
ATOM   12076 C CB  . HIS C 1 370 ? 141.689 155.270 126.530 1.00 75.32  ? 370 HIS C CB  1 
ATOM   12077 C CG  . HIS C 1 370 ? 140.682 154.244 126.086 1.00 73.61  ? 370 HIS C CG  1 
ATOM   12078 N ND1 . HIS C 1 370 ? 140.955 153.097 125.388 1.00 70.71  ? 370 HIS C ND1 1 
ATOM   12079 C CD2 . HIS C 1 370 ? 139.343 154.250 126.348 1.00 76.62  ? 370 HIS C CD2 1 
ATOM   12080 C CE1 . HIS C 1 370 ? 139.812 152.419 125.236 1.00 75.52  ? 370 HIS C CE1 1 
ATOM   12081 N NE2 . HIS C 1 370 ? 138.795 153.086 125.801 1.00 80.09  ? 370 HIS C NE2 1 
ATOM   12082 N N   . ARG C 1 371 ? 141.780 155.605 123.147 1.00 80.75  ? 371 ARG C N   1 
ATOM   12083 C CA  . ARG C 1 371 ? 142.194 155.179 121.799 1.00 76.94  ? 371 ARG C CA  1 
ATOM   12084 C C   . ARG C 1 371 ? 142.888 156.291 121.019 1.00 73.77  ? 371 ARG C C   1 
ATOM   12085 O O   . ARG C 1 371 ? 143.703 156.004 120.158 1.00 75.01  ? 371 ARG C O   1 
ATOM   12086 C CB  . ARG C 1 371 ? 140.990 154.678 120.994 1.00 76.30  ? 371 ARG C CB  1 
ATOM   12087 C CG  . ARG C 1 371 ? 140.409 153.358 121.514 1.00 75.76  ? 371 ARG C CG  1 
ATOM   12088 C CD  . ARG C 1 371 ? 139.253 152.846 120.650 1.00 77.90  ? 371 ARG C CD  1 
ATOM   12089 N NE  . ARG C 1 371 ? 139.686 152.539 119.272 1.00 86.24  ? 371 ARG C NE  1 
ATOM   12090 C CZ  . ARG C 1 371 ? 138.928 152.465 118.192 1.00 85.33  ? 371 ARG C CZ  1 
ATOM   12091 N NH1 . ARG C 1 371 ? 139.467 152.292 117.026 1.00 79.36  ? 371 ARG C NH1 1 
ATOM   12092 N NH2 . ARG C 1 371 ? 137.633 152.568 118.242 1.00 83.05  ? 371 ARG C NH2 1 
ATOM   12093 N N   . MET C 1 372 ? 142.595 157.556 121.319 1.00 67.83  ? 372 MET C N   1 
ATOM   12094 C CA  . MET C 1 372 ? 143.218 158.713 120.667 1.00 58.64  ? 372 MET C CA  1 
ATOM   12095 C C   . MET C 1 372 ? 144.638 159.014 121.154 1.00 70.24  ? 372 MET C C   1 
ATOM   12096 O O   . MET C 1 372 ? 145.480 159.384 120.346 1.00 77.58  ? 372 MET C O   1 
ATOM   12097 C CB  . MET C 1 372 ? 142.330 159.953 120.818 1.00 65.77  ? 372 MET C CB  1 
ATOM   12098 C CG  . MET C 1 372 ? 141.006 159.771 120.076 1.00 71.31  ? 372 MET C CG  1 
ATOM   12099 S SD  . MET C 1 372 ? 140.034 161.274 119.876 1.00 70.26  ? 372 MET C SD  1 
ATOM   12100 C CE  . MET C 1 372 ? 139.435 161.498 121.555 1.00 73.42  ? 372 MET C CE  1 
ATOM   12101 N N   . VAL C 1 373 ? 144.968 158.824 122.427 1.00 74.15  ? 373 VAL C N   1 
ATOM   12102 C CA  . VAL C 1 373 ? 146.335 159.097 122.910 1.00 69.04  ? 373 VAL C CA  1 
ATOM   12103 C C   . VAL C 1 373 ? 147.368 158.062 122.467 1.00 68.68  ? 373 VAL C C   1 
ATOM   12104 O O   . VAL C 1 373 ? 148.562 158.318 122.558 1.00 73.89  ? 373 VAL C O   1 
ATOM   12105 C CB  . VAL C 1 373 ? 146.379 159.250 124.431 1.00 64.21  ? 373 VAL C CB  1 
ATOM   12106 C CG1 . VAL C 1 373 ? 145.553 160.449 124.881 1.00 68.05  ? 373 VAL C CG1 1 
ATOM   12107 C CG2 . VAL C 1 373 ? 145.890 158.002 125.147 1.00 68.50  ? 373 VAL C CG2 1 
ATOM   12108 N N   . VAL C 1 374 ? 146.940 156.888 121.996 1.00 68.31  ? 374 VAL C N   1 
ATOM   12109 C CA  . VAL C 1 374 ? 147.835 155.821 121.516 1.00 67.77  ? 374 VAL C CA  1 
ATOM   12110 C C   . VAL C 1 374 ? 148.066 155.860 120.000 1.00 74.31  ? 374 VAL C C   1 
ATOM   12111 O O   . VAL C 1 374 ? 148.766 155.004 119.465 1.00 78.48  ? 374 VAL C O   1 
ATOM   12112 C CB  . VAL C 1 374 ? 147.402 154.430 122.005 1.00 72.60  ? 374 VAL C CB  1 
ATOM   12113 C CG1 . VAL C 1 374 ? 147.388 154.374 123.530 1.00 76.06  ? 374 VAL C CG1 1 
ATOM   12114 C CG2 . VAL C 1 374 ? 146.037 153.986 121.491 1.00 69.89  ? 374 VAL C CG2 1 
ATOM   12115 N N   . LEU C 1 375 ? 147.579 156.870 119.267 1.00 69.84  ? 375 LEU C N   1 
ATOM   12116 C CA  . LEU C 1 375 ? 147.936 157.117 117.857 1.00 63.45  ? 375 LEU C CA  1 
ATOM   12117 C C   . LEU C 1 375 ? 149.305 157.797 117.705 1.00 67.28  ? 375 LEU C C   1 
ATOM   12118 O O   . LEU C 1 375 ? 149.683 158.588 118.555 1.00 78.47  ? 375 LEU C O   1 
ATOM   12119 C CB  . LEU C 1 375 ? 146.894 158.037 117.206 1.00 65.37  ? 375 LEU C CB  1 
ATOM   12120 C CG  . LEU C 1 375 ? 145.448 157.533 117.212 1.00 67.35  ? 375 LEU C CG  1 
ATOM   12121 C CD1 . LEU C 1 375 ? 144.587 158.526 116.447 1.00 65.25  ? 375 LEU C CD1 1 
ATOM   12122 C CD2 . LEU C 1 375 ? 145.331 156.168 116.559 1.00 66.72  ? 375 LEU C CD2 1 
ATOM   12123 N N   . GLU C 1 376 ? 150.036 157.588 116.610 1.00 70.56  ? 376 GLU C N   1 
ATOM   12124 C CA  . GLU C 1 376 ? 151.183 158.454 116.276 1.00 76.05  ? 376 GLU C CA  1 
ATOM   12125 C C   . GLU C 1 376 ? 150.725 159.774 115.627 1.00 74.54  ? 376 GLU C C   1 
ATOM   12126 O O   . GLU C 1 376 ? 149.751 159.766 114.879 1.00 76.41  ? 376 GLU C O   1 
ATOM   12127 C CB  . GLU C 1 376 ? 152.188 157.732 115.369 1.00 75.37  ? 376 GLU C CB  1 
ATOM   12128 C CG  . GLU C 1 376 ? 152.783 156.444 115.957 1.00 77.88  ? 376 GLU C CG  1 
ATOM   12129 C CD  . GLU C 1 376 ? 153.419 156.571 117.355 1.00 84.38  ? 376 GLU C CD  1 
ATOM   12130 O OE1 . GLU C 1 376 ? 153.798 157.684 117.775 1.00 90.91  ? 376 GLU C OE1 1 
ATOM   12131 O OE2 . GLU C 1 376 ? 153.531 155.526 118.036 1.00 82.97  ? 376 GLU C OE2 1 
ATOM   12132 N N   . PRO C 1 377 ? 151.402 160.911 115.875 1.00 60.92  ? 377 PRO C N   1 
ATOM   12133 C CA  . PRO C 1 377 ? 152.595 161.078 116.705 1.00 57.86  ? 377 PRO C CA  1 
ATOM   12134 C C   . PRO C 1 377 ? 152.326 161.146 118.217 1.00 67.26  ? 377 PRO C C   1 
ATOM   12135 O O   . PRO C 1 377 ? 153.279 161.176 118.984 1.00 79.49  ? 377 PRO C O   1 
ATOM   12136 C CB  . PRO C 1 377 ? 153.198 162.397 116.227 1.00 65.46  ? 377 PRO C CB  1 
ATOM   12137 C CG  . PRO C 1 377 ? 151.970 163.226 115.872 1.00 60.83  ? 377 PRO C CG  1 
ATOM   12138 C CD  . PRO C 1 377 ? 151.037 162.182 115.272 1.00 58.30  ? 377 PRO C CD  1 
ATOM   12139 N N   . LEU C 1 378 ? 151.069 161.202 118.671 1.00 70.54  ? 378 LEU C N   1 
ATOM   12140 C CA  . LEU C 1 378 ? 150.681 161.453 120.066 1.00 62.55  ? 378 LEU C CA  1 
ATOM   12141 C C   . LEU C 1 378 ? 151.301 160.469 121.061 1.00 66.86  ? 378 LEU C C   1 
ATOM   12142 O O   . LEU C 1 378 ? 151.782 160.888 122.105 1.00 75.14  ? 378 LEU C O   1 
ATOM   12143 C CB  . LEU C 1 378 ? 149.146 161.426 120.177 1.00 61.71  ? 378 LEU C CB  1 
ATOM   12144 C CG  . LEU C 1 378 ? 148.437 162.743 119.859 1.00 60.67  ? 378 LEU C CG  1 
ATOM   12145 C CD1 . LEU C 1 378 ? 148.807 163.343 118.532 1.00 63.63  ? 378 LEU C CD1 1 
ATOM   12146 C CD2 . LEU C 1 378 ? 146.944 162.526 119.875 1.00 65.71  ? 378 LEU C CD2 1 
ATOM   12147 N N   . ASN C 1 379 ? 151.347 159.185 120.737 1.00 66.18  ? 379 ASN C N   1 
ATOM   12148 C CA  . ASN C 1 379 ? 151.973 158.130 121.531 1.00 69.12  ? 379 ASN C CA  1 
ATOM   12149 C C   . ASN C 1 379 ? 153.463 158.397 121.805 1.00 72.00  ? 379 ASN C C   1 
ATOM   12150 O O   . ASN C 1 379 ? 153.845 158.508 122.973 1.00 77.25  ? 379 ASN C O   1 
ATOM   12151 C CB  . ASN C 1 379 ? 151.737 156.796 120.824 1.00 65.91  ? 379 ASN C CB  1 
ATOM   12152 C CG  . ASN C 1 379 ? 152.438 155.635 121.493 1.00 74.84  ? 379 ASN C CG  1 
ATOM   12153 O OD1 . ASN C 1 379 ? 152.367 155.443 122.701 1.00 78.41  ? 379 ASN C OD1 1 
ATOM   12154 N ND2 . ASN C 1 379 ? 153.155 154.845 120.734 1.00 74.98  ? 379 ASN C ND2 1 
ATOM   12155 N N   . LYS C 1 380 ? 154.303 158.569 120.773 1.00 69.47  ? 380 LYS C N   1 
ATOM   12156 C CA  . LYS C 1 380 ? 155.719 158.917 120.973 1.00 62.26  ? 380 LYS C CA  1 
ATOM   12157 C C   . LYS C 1 380 ? 155.895 160.313 121.580 1.00 66.16  ? 380 LYS C C   1 
ATOM   12158 O O   . LYS C 1 380 ? 156.766 160.494 122.417 1.00 76.22  ? 380 LYS C O   1 
ATOM   12159 C CB  . LYS C 1 380 ? 156.512 158.754 119.666 1.00 61.53  ? 380 LYS C CB  1 
ATOM   12160 C CG  . LYS C 1 380 ? 158.026 158.833 119.933 1.00 73.27  ? 380 LYS C CG  1 
ATOM   12161 C CD  . LYS C 1 380 ? 158.898 158.985 118.681 1.00 80.11  ? 380 LYS C CD  1 
ATOM   12162 C CE  . LYS C 1 380 ? 160.327 159.312 119.133 1.00 74.20  ? 380 LYS C CE  1 
ATOM   12163 N NZ  . LYS C 1 380 ? 161.262 159.511 118.001 1.00 63.73  ? 380 LYS C NZ  1 
ATOM   12164 N N   . LEU C 1 381 ? 155.062 161.289 121.235 1.00 61.22  ? 381 LEU C N   1 
ATOM   12165 C CA  . LEU C 1 381 ? 155.107 162.640 121.798 1.00 57.16  ? 381 LEU C CA  1 
ATOM   12166 C C   . LEU C 1 381 ? 154.792 162.681 123.306 1.00 65.36  ? 381 LEU C C   1 
ATOM   12167 O O   . LEU C 1 381 ? 155.440 163.407 124.053 1.00 72.56  ? 381 LEU C O   1 
ATOM   12168 C CB  . LEU C 1 381 ? 154.130 163.493 120.981 1.00 58.97  ? 381 LEU C CB  1 
ATOM   12169 C CG  . LEU C 1 381 ? 154.092 164.988 121.314 1.00 63.58  ? 381 LEU C CG  1 
ATOM   12170 C CD1 . LEU C 1 381 ? 155.443 165.649 121.072 1.00 63.77  ? 381 LEU C CD1 1 
ATOM   12171 C CD2 . LEU C 1 381 ? 153.070 165.654 120.405 1.00 64.14  ? 381 LEU C CD2 1 
ATOM   12172 N N   . LEU C 1 382 ? 153.834 161.885 123.786 1.00 62.74  ? 382 LEU C N   1 
ATOM   12173 C CA  . LEU C 1 382 ? 153.513 161.747 125.196 1.00 59.46  ? 382 LEU C CA  1 
ATOM   12174 C C   . LEU C 1 382 ? 154.532 160.876 125.930 1.00 63.14  ? 382 LEU C C   1 
ATOM   12175 O O   . LEU C 1 382 ? 154.796 161.136 127.096 1.00 71.67  ? 382 LEU C O   1 
ATOM   12176 C CB  . LEU C 1 382 ? 152.091 161.190 125.326 1.00 60.89  ? 382 LEU C CB  1 
ATOM   12177 C CG  . LEU C 1 382 ? 151.003 162.191 124.912 1.00 57.14  ? 382 LEU C CG  1 
ATOM   12178 C CD1 . LEU C 1 382 ? 149.690 161.449 124.718 1.00 55.24  ? 382 LEU C CD1 1 
ATOM   12179 C CD2 . LEU C 1 382 ? 150.835 163.280 125.965 1.00 66.99  ? 382 LEU C CD2 1 
ATOM   12180 N N   . GLN C 1 383 ? 155.153 159.893 125.276 1.00 66.78  ? 383 GLN C N   1 
ATOM   12181 C CA  . GLN C 1 383 ? 156.278 159.161 125.859 1.00 62.79  ? 383 GLN C CA  1 
ATOM   12182 C C   . GLN C 1 383 ? 157.502 160.062 126.050 1.00 70.93  ? 383 GLN C C   1 
ATOM   12183 O O   . GLN C 1 383 ? 158.120 160.045 127.103 1.00 80.68  ? 383 GLN C O   1 
ATOM   12184 C CB  . GLN C 1 383 ? 156.619 157.947 124.991 1.00 66.02  ? 383 GLN C CB  1 
ATOM   12185 C CG  . GLN C 1 383 ? 157.661 157.032 125.644 1.00 70.75  ? 383 GLN C CG  1 
ATOM   12186 C CD  . GLN C 1 383 ? 157.168 156.358 126.924 1.00 79.15  ? 383 GLN C CD  1 
ATOM   12187 O OE1 . GLN C 1 383 ? 156.090 155.777 126.978 1.00 84.66  ? 383 GLN C OE1 1 
ATOM   12188 N NE2 . GLN C 1 383 ? 157.919 156.384 127.994 1.00 73.97  ? 383 GLN C NE2 1 
ATOM   12189 N N   . GLU C 1 384 ? 157.839 160.883 125.059 1.00 69.62  ? 384 GLU C N   1 
ATOM   12190 C CA  . GLU C 1 384 ? 158.907 161.878 125.137 1.00 63.34  ? 384 GLU C CA  1 
ATOM   12191 C C   . GLU C 1 384 ? 158.681 162.888 126.266 1.00 71.67  ? 384 GLU C C   1 
ATOM   12192 O O   . GLU C 1 384 ? 159.598 163.172 127.028 1.00 75.12  ? 384 GLU C O   1 
ATOM   12193 C CB  . GLU C 1 384 ? 158.991 162.609 123.792 1.00 67.36  ? 384 GLU C CB  1 
ATOM   12194 C CG  . GLU C 1 384 ? 159.737 161.819 122.708 1.00 78.98  ? 384 GLU C CG  1 
ATOM   12195 C CD  . GLU C 1 384 ? 161.173 162.263 122.407 1.00 84.22  ? 384 GLU C CD  1 
ATOM   12196 O OE1 . GLU C 1 384 ? 161.639 163.319 122.891 1.00 86.08  ? 384 GLU C OE1 1 
ATOM   12197 O OE2 . GLU C 1 384 ? 161.846 161.548 121.652 1.00 77.41  ? 384 GLU C OE2 1 
ATOM   12198 N N   . LYS C 1 385 ? 157.457 163.400 126.430 1.00 77.50  ? 385 LYS C N   1 
ATOM   12199 C CA  . LYS C 1 385 ? 157.095 164.267 127.559 1.00 65.94  ? 385 LYS C CA  1 
ATOM   12200 C C   . LYS C 1 385 ? 157.158 163.527 128.894 1.00 65.41  ? 385 LYS C C   1 
ATOM   12201 O O   . LYS C 1 385 ? 157.697 164.063 129.854 1.00 72.13  ? 385 LYS C O   1 
ATOM   12202 C CB  . LYS C 1 385 ? 155.697 164.849 127.338 1.00 67.27  ? 385 LYS C CB  1 
ATOM   12203 C CG  . LYS C 1 385 ? 155.649 165.917 126.244 1.00 69.01  ? 385 LYS C CG  1 
ATOM   12204 C CD  . LYS C 1 385 ? 154.207 166.347 125.955 1.00 69.28  ? 385 LYS C CD  1 
ATOM   12205 C CE  . LYS C 1 385 ? 154.113 167.345 124.803 1.00 76.61  ? 385 LYS C CE  1 
ATOM   12206 N NZ  . LYS C 1 385 ? 154.815 168.606 125.080 1.00 66.90  ? 385 LYS C NZ  1 
ATOM   12207 N N   . TRP C 1 386 ? 156.652 162.299 128.977 1.00 65.35  ? 386 TRP C N   1 
ATOM   12208 C CA  . TRP C 1 386 ? 156.692 161.476 130.182 1.00 65.50  ? 386 TRP C CA  1 
ATOM   12209 C C   . TRP C 1 386 ? 158.122 161.213 130.643 1.00 66.38  ? 386 TRP C C   1 
ATOM   12210 O O   . TRP C 1 386 ? 158.445 161.444 131.797 1.00 75.97  ? 386 TRP C O   1 
ATOM   12211 C CB  . TRP C 1 386 ? 155.941 160.163 129.943 1.00 63.72  ? 386 TRP C CB  1 
ATOM   12212 C CG  . TRP C 1 386 ? 156.025 159.197 131.075 1.00 68.29  ? 386 TRP C CG  1 
ATOM   12213 C CD1 . TRP C 1 386 ? 156.816 158.104 131.120 1.00 69.23  ? 386 TRP C CD1 1 
ATOM   12214 C CD2 . TRP C 1 386 ? 155.396 159.292 132.383 1.00 73.63  ? 386 TRP C CD2 1 
ATOM   12215 N NE1 . TRP C 1 386 ? 156.710 157.511 132.362 1.00 70.90  ? 386 TRP C NE1 1 
ATOM   12216 C CE2 . TRP C 1 386 ? 155.867 158.219 133.188 1.00 73.13  ? 386 TRP C CE2 1 
ATOM   12217 C CE3 . TRP C 1 386 ? 154.513 160.207 132.986 1.00 70.63  ? 386 TRP C CE3 1 
ATOM   12218 C CZ2 . TRP C 1 386 ? 155.475 158.066 134.520 1.00 69.39  ? 386 TRP C CZ2 1 
ATOM   12219 C CZ3 . TRP C 1 386 ? 154.107 160.056 134.320 1.00 64.50  ? 386 TRP C CZ3 1 
ATOM   12220 C CH2 . TRP C 1 386 ? 154.582 158.988 135.085 1.00 68.30  ? 386 TRP C CH2 1 
ATOM   12221 N N   . ASP C 1 387 ? 159.018 160.835 129.743 1.00 66.34  ? 387 ASP C N   1 
ATOM   12222 C CA  . ASP C 1 387 ? 160.438 160.618 130.033 1.00 66.65  ? 387 ASP C CA  1 
ATOM   12223 C C   . ASP C 1 387 ? 161.136 161.878 130.578 1.00 69.13  ? 387 ASP C C   1 
ATOM   12224 O O   . ASP C 1 387 ? 162.002 161.777 131.442 1.00 75.06  ? 387 ASP C O   1 
ATOM   12225 C CB  . ASP C 1 387 ? 161.164 160.135 128.770 1.00 74.51  ? 387 ASP C CB  1 
ATOM   12226 C CG  . ASP C 1 387 ? 160.732 158.764 128.236 1.00 77.05  ? 387 ASP C CG  1 
ATOM   12227 O OD1 . ASP C 1 387 ? 160.026 158.008 128.938 1.00 71.85  ? 387 ASP C OD1 1 
ATOM   12228 O OD2 . ASP C 1 387 ? 161.174 158.405 127.123 1.00 75.68  ? 387 ASP C OD2 1 
ATOM   12229 N N   . ARG C 1 388 ? 160.765 163.074 130.106 1.00 80.32  ? 388 ARG C N   1 
ATOM   12230 C CA  . ARG C 1 388 ? 161.253 164.351 130.652 1.00 78.76  ? 388 ARG C CA  1 
ATOM   12231 C C   . ARG C 1 388 ? 160.670 164.705 132.021 1.00 85.00  ? 388 ARG C C   1 
ATOM   12232 O O   . ARG C 1 388 ? 161.245 165.600 132.671 1.00 83.99  ? 388 ARG C O   1 
ATOM   12233 C CB  . ARG C 1 388 ? 161.018 165.490 129.643 1.00 78.62  ? 388 ARG C CB  1 
ATOM   12234 C CG  . ARG C 1 388 ? 161.980 165.378 128.454 1.00 85.28  ? 388 ARG C CG  1 
ATOM   12235 C CD  . ARG C 1 388 ? 161.980 166.612 127.531 1.00 84.40  ? 388 ARG C CD  1 
ATOM   12236 N NE  . ARG C 1 388 ? 160.667 166.656 126.905 1.00 90.38  ? 388 ARG C NE  1 
ATOM   12237 C CZ  . ARG C 1 388 ? 160.282 165.846 125.925 1.00 95.63  ? 388 ARG C CZ  1 
ATOM   12238 N NH1 . ARG C 1 388 ? 159.062 165.943 125.425 1.00 90.77  ? 388 ARG C NH1 1 
ATOM   12239 N NH2 . ARG C 1 388 ? 161.113 164.934 125.455 1.00 90.09  ? 388 ARG C NH2 1 
ATOM   12240 N N   . LEU C 1 389 ? 159.585 164.061 132.454 1.00 78.44  ? 389 LEU C N   1 
ATOM   12241 C CA  . LEU C 1 389 ? 158.822 164.412 133.658 1.00 66.38  ? 389 LEU C CA  1 
ATOM   12242 C C   . LEU C 1 389 ? 158.700 163.284 134.692 1.00 70.34  ? 389 LEU C C   1 
ATOM   12243 O O   . LEU C 1 389 ? 158.276 163.552 135.808 1.00 81.19  ? 389 LEU C O   1 
ATOM   12244 C CB  . LEU C 1 389 ? 157.440 164.928 133.238 1.00 68.35  ? 389 LEU C CB  1 
ATOM   12245 C CG  . LEU C 1 389 ? 157.453 166.265 132.480 1.00 71.97  ? 389 LEU C CG  1 
ATOM   12246 C CD1 . LEU C 1 389 ? 156.090 166.511 131.851 1.00 71.14  ? 389 LEU C CD1 1 
ATOM   12247 C CD2 . LEU C 1 389 ? 157.774 167.436 133.404 1.00 66.83  ? 389 LEU C CD2 1 
ATOM   12248 N N   . VAL C 1 390 ? 159.108 162.049 134.401 1.00 71.13  ? 390 VAL C N   1 
ATOM   12249 C CA  . VAL C 1 390 ? 159.011 160.898 135.309 1.00 71.05  ? 390 VAL C CA  1 
ATOM   12250 C C   . VAL C 1 390 ? 159.755 161.121 136.635 1.00 76.47  ? 390 VAL C C   1 
ATOM   12251 O O   . VAL C 1 390 ? 159.276 160.737 137.696 1.00 78.84  ? 390 VAL C O   1 
ATOM   12252 C CB  . VAL C 1 390 ? 159.439 159.623 134.561 1.00 63.94  ? 390 VAL C CB  1 
ATOM   12253 C CG1 . VAL C 1 390 ? 160.921 159.598 134.192 1.00 67.98  ? 390 VAL C CG1 1 
ATOM   12254 C CG2 . VAL C 1 390 ? 159.129 158.365 135.360 1.00 69.65  ? 390 VAL C CG2 1 
ATOM   12255 N N   . SER C 1 391 ? 160.869 161.852 136.626 1.00 77.10  ? 391 SER C N   1 
ATOM   12256 C CA  . SER C 1 391 ? 161.585 162.270 137.838 1.00 70.17  ? 391 SER C CA  1 
ATOM   12257 C C   . SER C 1 391 ? 160.830 163.326 138.653 1.00 74.56  ? 391 SER C C   1 
ATOM   12258 O O   . SER C 1 391 ? 160.933 163.329 139.878 1.00 87.90  ? 391 SER C O   1 
ATOM   12259 C CB  . SER C 1 391 ? 162.965 162.803 137.457 1.00 73.69  ? 391 SER C CB  1 
ATOM   12260 O OG  . SER C 1 391 ? 162.847 163.913 136.589 1.00 81.83  ? 391 SER C OG  1 
ATOM   12261 N N   . ARG C 1 392 ? 160.013 164.174 138.021 1.00 74.12  ? 392 ARG C N   1 
ATOM   12262 C CA  . ARG C 1 392 ? 159.097 165.112 138.695 1.00 63.71  ? 392 ARG C CA  1 
ATOM   12263 C C   . ARG C 1 392 ? 157.892 164.378 139.274 1.00 71.05  ? 392 ARG C C   1 
ATOM   12264 O O   . ARG C 1 392 ? 157.487 164.655 140.392 1.00 88.30  ? 392 ARG C O   1 
ATOM   12265 C CB  . ARG C 1 392 ? 158.663 166.205 137.710 1.00 70.73  ? 392 ARG C CB  1 
ATOM   12266 C CG  . ARG C 1 392 ? 158.200 167.471 138.433 1.00 69.16  ? 392 ARG C CG  1 
ATOM   12267 C CD  . ARG C 1 392 ? 157.801 168.548 137.414 1.00 82.01  ? 392 ARG C CD  1 
ATOM   12268 N NE  . ARG C 1 392 ? 157.770 169.890 138.020 1.00 87.69  ? 392 ARG C NE  1 
ATOM   12269 C CZ  . ARG C 1 392 ? 158.796 170.710 138.174 1.00 92.58  ? 392 ARG C CZ  1 
ATOM   12270 N NH1 . ARG C 1 392 ? 158.635 171.886 138.704 1.00 88.09  ? 392 ARG C NH1 1 
ATOM   12271 N NH2 . ARG C 1 392 ? 160.003 170.397 137.807 1.00 88.13  ? 392 ARG C NH2 1 
ATOM   12272 N N   . PHE C 1 393 ? 157.371 163.380 138.571 1.00 62.33  ? 393 PHE C N   1 
ATOM   12273 C CA  . PHE C 1 393 ? 156.305 162.511 139.053 1.00 55.11  ? 393 PHE C CA  1 
ATOM   12274 C C   . PHE C 1 393 ? 156.715 161.768 140.325 1.00 65.53  ? 393 PHE C C   1 
ATOM   12275 O O   . PHE C 1 393 ? 155.988 161.792 141.314 1.00 77.66  ? 393 PHE C O   1 
ATOM   12276 C CB  . PHE C 1 393 ? 155.903 161.536 137.946 1.00 56.92  ? 393 PHE C CB  1 
ATOM   12277 C CG  . PHE C 1 393 ? 154.698 160.699 138.294 1.00 60.48  ? 393 PHE C CG  1 
ATOM   12278 C CD1 . PHE C 1 393 ? 153.407 161.221 138.100 1.00 67.83  ? 393 PHE C CD1 1 
ATOM   12279 C CD2 . PHE C 1 393 ? 154.854 159.406 138.819 1.00 57.70  ? 393 PHE C CD2 1 
ATOM   12280 C CE1 . PHE C 1 393 ? 152.283 160.446 138.414 1.00 62.48  ? 393 PHE C CE1 1 
ATOM   12281 C CE2 . PHE C 1 393 ? 153.728 158.636 139.136 1.00 62.25  ? 393 PHE C CE2 1 
ATOM   12282 C CZ  . PHE C 1 393 ? 152.443 159.152 138.919 1.00 58.32  ? 393 PHE C CZ  1 
ATOM   12283 N N   . PHE C 1 394 ? 157.903 161.156 140.349 1.00 71.25  ? 394 PHE C N   1 
ATOM   12284 C CA  . PHE C 1 394 ? 158.374 160.442 141.532 1.00 66.07  ? 394 PHE C CA  1 
ATOM   12285 C C   . PHE C 1 394 ? 158.911 161.345 142.650 1.00 62.38  ? 394 PHE C C   1 
ATOM   12286 O O   . PHE C 1 394 ? 158.803 160.981 143.814 1.00 77.72  ? 394 PHE C O   1 
ATOM   12287 C CB  . PHE C 1 394 ? 159.315 159.313 141.122 1.00 63.62  ? 394 PHE C CB  1 
ATOM   12288 C CG  . PHE C 1 394 ? 158.573 158.194 140.411 1.00 74.04  ? 394 PHE C CG  1 
ATOM   12289 C CD1 . PHE C 1 394 ? 157.564 157.488 141.088 1.00 72.56  ? 394 PHE C CD1 1 
ATOM   12290 C CD2 . PHE C 1 394 ? 158.857 157.873 139.074 1.00 66.45  ? 394 PHE C CD2 1 
ATOM   12291 C CE1 . PHE C 1 394 ? 156.834 156.482 140.439 1.00 69.15  ? 394 PHE C CE1 1 
ATOM   12292 C CE2 . PHE C 1 394 ? 158.138 156.856 138.426 1.00 65.36  ? 394 PHE C CE2 1 
ATOM   12293 C CZ  . PHE C 1 394 ? 157.132 156.161 139.108 1.00 70.08  ? 394 PHE C CZ  1 
ATOM   12294 N N   . PHE C 1 395 ? 159.392 162.549 142.353 1.00 60.95  ? 395 PHE C N   1 
ATOM   12295 C CA  . PHE C 1 395 ? 159.615 163.573 143.370 1.00 62.88  ? 395 PHE C CA  1 
ATOM   12296 C C   . PHE C 1 395 ? 158.303 163.983 144.049 1.00 69.35  ? 395 PHE C C   1 
ATOM   12297 O O   . PHE C 1 395 ? 158.215 163.983 145.275 1.00 81.93  ? 395 PHE C O   1 
ATOM   12298 C CB  . PHE C 1 395 ? 160.318 164.767 142.723 1.00 65.10  ? 395 PHE C CB  1 
ATOM   12299 C CG  . PHE C 1 395 ? 160.520 165.943 143.652 1.00 69.40  ? 395 PHE C CG  1 
ATOM   12300 C CD1 . PHE C 1 395 ? 161.476 165.873 144.677 1.00 75.73  ? 395 PHE C CD1 1 
ATOM   12301 C CD2 . PHE C 1 395 ? 159.756 167.108 143.488 1.00 69.17  ? 395 PHE C CD2 1 
ATOM   12302 C CE1 . PHE C 1 395 ? 161.666 166.965 145.537 1.00 73.63  ? 395 PHE C CE1 1 
ATOM   12303 C CE2 . PHE C 1 395 ? 159.956 168.204 144.339 1.00 74.04  ? 395 PHE C CE2 1 
ATOM   12304 C CZ  . PHE C 1 395 ? 160.911 168.134 145.363 1.00 74.80  ? 395 PHE C CZ  1 
ATOM   12305 N N   . ASN C 1 396 ? 157.247 164.247 143.281 1.00 69.09  ? 396 ASN C N   1 
ATOM   12306 C CA  . ASN C 1 396 ? 155.925 164.572 143.806 1.00 64.78  ? 396 ASN C CA  1 
ATOM   12307 C C   . ASN C 1 396 ? 155.340 163.449 144.685 1.00 70.02  ? 396 ASN C C   1 
ATOM   12308 O O   . ASN C 1 396 ? 154.753 163.726 145.728 1.00 77.50  ? 396 ASN C O   1 
ATOM   12309 C CB  . ASN C 1 396 ? 154.993 164.882 142.626 1.00 69.06  ? 396 ASN C CB  1 
ATOM   12310 C CG  . ASN C 1 396 ? 155.278 166.187 141.900 1.00 72.77  ? 396 ASN C CG  1 
ATOM   12311 O OD1 . ASN C 1 396 ? 156.182 166.948 142.204 1.00 75.36  ? 396 ASN C OD1 1 
ATOM   12312 N ND2 . ASN C 1 396 ? 154.460 166.528 140.936 1.00 73.51  ? 396 ASN C ND2 1 
ATOM   12313 N N   . PHE C 1 397 ? 155.552 162.189 144.306 1.00 58.12  ? 397 PHE C N   1 
ATOM   12314 C CA  . PHE C 1 397 ? 155.248 160.997 145.099 1.00 58.37  ? 397 PHE C CA  1 
ATOM   12315 C C   . PHE C 1 397 ? 156.052 160.907 146.400 1.00 65.29  ? 397 PHE C C   1 
ATOM   12316 O O   . PHE C 1 397 ? 155.474 160.631 147.445 1.00 73.03  ? 397 PHE C O   1 
ATOM   12317 C CB  . PHE C 1 397 ? 155.509 159.760 144.244 1.00 55.63  ? 397 PHE C CB  1 
ATOM   12318 C CG  . PHE C 1 397 ? 155.441 158.429 144.968 1.00 64.70  ? 397 PHE C CG  1 
ATOM   12319 C CD1 . PHE C 1 397 ? 154.270 158.039 145.636 1.00 64.79  ? 397 PHE C CD1 1 
ATOM   12320 C CD2 . PHE C 1 397 ? 156.552 157.569 144.963 1.00 69.09  ? 397 PHE C CD2 1 
ATOM   12321 C CE1 . PHE C 1 397 ? 154.191 156.785 146.252 1.00 56.18  ? 397 PHE C CE1 1 
ATOM   12322 C CE2 . PHE C 1 397 ? 156.481 156.320 145.597 1.00 67.92  ? 397 PHE C CE2 1 
ATOM   12323 C CZ  . PHE C 1 397 ? 155.297 155.925 146.232 1.00 65.24  ? 397 PHE C CZ  1 
ATOM   12324 N N   . ALA C 1 398 ? 157.362 161.161 146.373 1.00 69.65  ? 398 ALA C N   1 
ATOM   12325 C CA  . ALA C 1 398 ? 158.216 161.143 147.555 1.00 56.41  ? 398 ALA C CA  1 
ATOM   12326 C C   . ALA C 1 398 ? 157.867 162.255 148.557 1.00 62.99  ? 398 ALA C C   1 
ATOM   12327 O O   . ALA C 1 398 ? 157.815 161.995 149.754 1.00 83.39  ? 398 ALA C O   1 
ATOM   12328 C CB  . ALA C 1 398 ? 159.670 161.225 147.104 1.00 55.94  ? 398 ALA C CB  1 
ATOM   12329 N N   . CYS C 1 399 ? 157.544 163.469 148.109 1.00 59.27  ? 399 CYS C N   1 
ATOM   12330 C CA  . CYS C 1 399 ? 157.004 164.508 148.990 1.00 67.71  ? 399 CYS C CA  1 
ATOM   12331 C C   . CYS C 1 399 ? 155.697 164.074 149.661 1.00 66.36  ? 399 CYS C C   1 
ATOM   12332 O O   . CYS C 1 399 ? 155.512 164.311 150.851 1.00 76.94  ? 399 CYS C O   1 
ATOM   12333 C CB  . CYS C 1 399 ? 156.752 165.776 148.182 1.00 71.04  ? 399 CYS C CB  1 
ATOM   12334 S SG  . CYS C 1 399 ? 158.305 166.541 147.688 1.00 72.59  ? 399 CYS C SG  1 
ATOM   12335 N N   . TYR C 1 400 ? 154.819 163.416 148.912 1.00 54.62  ? 400 TYR C N   1 
ATOM   12336 C CA  . TYR C 1 400 ? 153.552 162.947 149.438 1.00 51.92  ? 400 TYR C CA  1 
ATOM   12337 C C   . TYR C 1 400 ? 153.727 161.749 150.384 1.00 65.12  ? 400 TYR C C   1 
ATOM   12338 O O   . TYR C 1 400 ? 153.057 161.689 151.405 1.00 80.26  ? 400 TYR C O   1 
ATOM   12339 C CB  . TYR C 1 400 ? 152.614 162.667 148.275 1.00 57.47  ? 400 TYR C CB  1 
ATOM   12340 C CG  . TYR C 1 400 ? 151.194 162.443 148.729 1.00 62.86  ? 400 TYR C CG  1 
ATOM   12341 C CD1 . TYR C 1 400 ? 150.368 163.534 149.039 1.00 59.80  ? 400 TYR C CD1 1 
ATOM   12342 C CD2 . TYR C 1 400 ? 150.726 161.135 148.895 1.00 57.33  ? 400 TYR C CD2 1 
ATOM   12343 C CE1 . TYR C 1 400 ? 149.072 163.306 149.529 1.00 51.09  ? 400 TYR C CE1 1 
ATOM   12344 C CE2 . TYR C 1 400 ? 149.434 160.899 149.372 1.00 50.80  ? 400 TYR C CE2 1 
ATOM   12345 C CZ  . TYR C 1 400 ? 148.614 161.991 149.698 1.00 53.91  ? 400 TYR C CZ  1 
ATOM   12346 O OH  . TYR C 1 400 ? 147.396 161.767 150.224 1.00 66.93  ? 400 TYR C OH  1 
ATOM   12347 N N   . LEU C 1 401 ? 154.688 160.850 150.152 1.00 55.25  ? 401 LEU C N   1 
ATOM   12348 C CA  . LEU C 1 401 ? 155.096 159.831 151.118 1.00 48.34  ? 401 LEU C CA  1 
ATOM   12349 C C   . LEU C 1 401 ? 155.607 160.449 152.424 1.00 55.61  ? 401 LEU C C   1 
ATOM   12350 O O   . LEU C 1 401 ? 155.209 160.016 153.494 1.00 71.64  ? 401 LEU C O   1 
ATOM   12351 C CB  . LEU C 1 401 ? 156.228 158.968 150.543 1.00 63.08  ? 401 LEU C CB  1 
ATOM   12352 C CG  . LEU C 1 401 ? 155.823 157.776 149.686 1.00 66.12  ? 401 LEU C CG  1 
ATOM   12353 C CD1 . LEU C 1 401 ? 157.097 157.148 149.128 1.00 62.24  ? 401 LEU C CD1 1 
ATOM   12354 C CD2 . LEU C 1 401 ? 155.114 156.705 150.510 1.00 62.20  ? 401 LEU C CD2 1 
ATOM   12355 N N   . VAL C 1 402 ? 156.479 161.453 152.364 1.00 58.65  ? 402 VAL C N   1 
ATOM   12356 C CA  . VAL C 1 402 ? 157.018 162.153 153.541 1.00 62.73  ? 402 VAL C CA  1 
ATOM   12357 C C   . VAL C 1 402 ? 155.920 162.886 154.304 1.00 64.13  ? 402 VAL C C   1 
ATOM   12358 O O   . VAL C 1 402 ? 155.870 162.807 155.524 1.00 74.10  ? 402 VAL C O   1 
ATOM   12359 C CB  . VAL C 1 402 ? 158.158 163.104 153.139 1.00 62.15  ? 402 VAL C CB  1 
ATOM   12360 C CG1 . VAL C 1 402 ? 158.588 164.026 154.281 1.00 69.06  ? 402 VAL C CG1 1 
ATOM   12361 C CG2 . VAL C 1 402 ? 159.380 162.291 152.714 1.00 57.83  ? 402 VAL C CG2 1 
ATOM   12362 N N   . TYR C 1 403 ? 155.006 163.560 153.605 1.00 64.93  ? 403 TYR C N   1 
ATOM   12363 C CA  . TYR C 1 403 ? 153.810 164.153 154.195 1.00 56.12  ? 403 TYR C CA  1 
ATOM   12364 C C   . TYR C 1 403 ? 152.932 163.088 154.857 1.00 61.37  ? 403 TYR C C   1 
ATOM   12365 O O   . TYR C 1 403 ? 152.554 163.266 156.007 1.00 79.53  ? 403 TYR C O   1 
ATOM   12366 C CB  . TYR C 1 403 ? 153.061 164.945 153.118 1.00 67.58  ? 403 TYR C CB  1 
ATOM   12367 C CG  . TYR C 1 403 ? 151.633 165.360 153.430 1.00 70.42  ? 403 TYR C CG  1 
ATOM   12368 C CD1 . TYR C 1 403 ? 151.362 166.415 154.323 1.00 61.54  ? 403 TYR C CD1 1 
ATOM   12369 C CD2 . TYR C 1 403 ? 150.570 164.718 152.771 1.00 72.54  ? 403 TYR C CD2 1 
ATOM   12370 C CE1 . TYR C 1 403 ? 150.033 166.830 154.543 1.00 58.00  ? 403 TYR C CE1 1 
ATOM   12371 C CE2 . TYR C 1 403 ? 149.245 165.127 152.988 1.00 66.42  ? 403 TYR C CE2 1 
ATOM   12372 C CZ  . TYR C 1 403 ? 148.975 166.194 153.865 1.00 63.57  ? 403 TYR C CZ  1 
ATOM   12373 O OH  . TYR C 1 403 ? 147.700 166.621 154.036 1.00 74.72  ? 403 TYR C OH  1 
ATOM   12374 N N   . MET C 1 404 ? 152.674 161.948 154.212 1.00 55.75  ? 404 MET C N   1 
ATOM   12375 C CA  . MET C 1 404 ? 151.896 160.858 154.811 1.00 65.40  ? 404 MET C CA  1 
ATOM   12376 C C   . MET C 1 404 ? 152.613 160.094 155.932 1.00 70.48  ? 404 MET C C   1 
ATOM   12377 O O   . MET C 1 404 ? 151.954 159.607 156.849 1.00 78.00  ? 404 MET C O   1 
ATOM   12378 C CB  . MET C 1 404 ? 151.391 159.895 153.730 1.00 54.05  ? 404 MET C CB  1 
ATOM   12379 C CG  . MET C 1 404 ? 150.246 160.489 152.908 1.00 61.50  ? 404 MET C CG  1 
ATOM   12380 S SD  . MET C 1 404 ? 148.865 161.228 153.831 1.00 63.28  ? 404 MET C SD  1 
ATOM   12381 C CE  . MET C 1 404 ? 148.446 159.906 154.987 1.00 69.76  ? 404 MET C CE  1 
ATOM   12382 N N   . PHE C 1 405 ? 153.940 160.033 155.937 1.00 66.03  ? 405 PHE C N   1 
ATOM   12383 C CA  . PHE C 1 405 ? 154.723 159.540 157.068 1.00 65.96  ? 405 PHE C CA  1 
ATOM   12384 C C   . PHE C 1 405 ? 154.551 160.451 158.291 1.00 68.62  ? 405 PHE C C   1 
ATOM   12385 O O   . PHE C 1 405 ? 154.130 159.980 159.344 1.00 73.67  ? 405 PHE C O   1 
ATOM   12386 C CB  . PHE C 1 405 ? 156.189 159.407 156.644 1.00 62.93  ? 405 PHE C CB  1 
ATOM   12387 C CG  . PHE C 1 405 ? 157.130 158.993 157.754 1.00 77.51  ? 405 PHE C CG  1 
ATOM   12388 C CD1 . PHE C 1 405 ? 157.321 157.635 158.053 1.00 78.09  ? 405 PHE C CD1 1 
ATOM   12389 C CD2 . PHE C 1 405 ? 157.808 159.972 158.501 1.00 80.06  ? 405 PHE C CD2 1 
ATOM   12390 C CE1 . PHE C 1 405 ? 158.173 157.254 159.103 1.00 77.43  ? 405 PHE C CE1 1 
ATOM   12391 C CE2 . PHE C 1 405 ? 158.651 159.594 159.557 1.00 75.06  ? 405 PHE C CE2 1 
ATOM   12392 C CZ  . PHE C 1 405 ? 158.834 158.235 159.858 1.00 75.07  ? 405 PHE C CZ  1 
ATOM   12393 N N   . ILE C 1 406 ? 154.775 161.761 158.142 1.00 68.69  ? 406 ILE C N   1 
ATOM   12394 C CA  . ILE C 1 406 ? 154.556 162.777 159.175 1.00 65.33  ? 406 ILE C CA  1 
ATOM   12395 C C   . ILE C 1 406 ? 153.098 162.758 159.647 1.00 69.17  ? 406 ILE C C   1 
ATOM   12396 O O   . ILE C 1 406 ? 152.858 162.732 160.847 1.00 87.94  ? 406 ILE C O   1 
ATOM   12397 C CB  . ILE C 1 406 ? 154.993 164.169 158.670 1.00 67.21  ? 406 ILE C CB  1 
ATOM   12398 C CG1 . ILE C 1 406 ? 156.518 164.205 158.450 1.00 68.58  ? 406 ILE C CG1 1 
ATOM   12399 C CG2 . ILE C 1 406 ? 154.588 165.285 159.642 1.00 68.28  ? 406 ILE C CG2 1 
ATOM   12400 C CD1 . ILE C 1 406 ? 156.974 165.363 157.563 1.00 74.99  ? 406 ILE C CD1 1 
ATOM   12401 N N   . PHE C 1 407 ? 152.123 162.687 158.740 1.00 60.96  ? 407 PHE C N   1 
ATOM   12402 C CA  . PHE C 1 407 ? 150.710 162.573 159.092 1.00 67.32  ? 407 PHE C CA  1 
ATOM   12403 C C   . PHE C 1 407 ? 150.463 161.362 159.992 1.00 79.83  ? 407 PHE C C   1 
ATOM   12404 O O   . PHE C 1 407 ? 149.771 161.460 161.000 1.00 84.43  ? 407 PHE C O   1 
ATOM   12405 C CB  . PHE C 1 407 ? 149.871 162.490 157.811 1.00 71.22  ? 407 PHE C CB  1 
ATOM   12406 C CG  . PHE C 1 407 ? 148.497 163.112 157.896 1.00 76.40  ? 407 PHE C CG  1 
ATOM   12407 C CD1 . PHE C 1 407 ? 147.525 162.630 158.787 1.00 75.16  ? 407 PHE C CD1 1 
ATOM   12408 C CD2 . PHE C 1 407 ? 148.189 164.198 157.068 1.00 76.93  ? 407 PHE C CD2 1 
ATOM   12409 C CE1 . PHE C 1 407 ? 146.262 163.232 158.846 1.00 73.49  ? 407 PHE C CE1 1 
ATOM   12410 C CE2 . PHE C 1 407 ? 146.931 164.801 157.135 1.00 74.88  ? 407 PHE C CE2 1 
ATOM   12411 C CZ  . PHE C 1 407 ? 145.965 164.325 158.025 1.00 70.98  ? 407 PHE C CZ  1 
ATOM   12412 N N   . THR C 1 408 ? 151.061 160.217 159.671 1.00 75.99  ? 408 THR C N   1 
ATOM   12413 C CA  . THR C 1 408 ? 150.869 158.965 160.411 1.00 73.29  ? 408 THR C CA  1 
ATOM   12414 C C   . THR C 1 408 ? 151.538 158.981 161.786 1.00 73.79  ? 408 THR C C   1 
ATOM   12415 O O   . THR C 1 408 ? 150.906 158.598 162.760 1.00 79.83  ? 408 THR C O   1 
ATOM   12416 C CB  . THR C 1 408 ? 151.368 157.790 159.567 1.00 67.06  ? 408 THR C CB  1 
ATOM   12417 O OG1 . THR C 1 408 ? 150.686 157.801 158.341 1.00 69.35  ? 408 THR C OG1 1 
ATOM   12418 C CG2 . THR C 1 408 ? 151.113 156.432 160.198 1.00 64.39  ? 408 THR C CG2 1 
ATOM   12419 N N   . VAL C 1 409 ? 152.773 159.475 161.885 1.00 66.22  ? 409 VAL C N   1 
ATOM   12420 C CA  . VAL C 1 409 ? 153.588 159.636 163.091 1.00 68.55  ? 409 VAL C CA  1 
ATOM   12421 C C   . VAL C 1 409 ? 153.023 160.695 164.042 1.00 71.93  ? 409 VAL C C   1 
ATOM   12422 O O   . VAL C 1 409 ? 153.397 160.689 165.210 1.00 83.55  ? 409 VAL C O   1 
ATOM   12423 C CB  . VAL C 1 409 ? 155.043 159.921 162.668 1.00 74.79  ? 409 VAL C CB  1 
ATOM   12424 C CG1 . VAL C 1 409 ? 155.990 160.373 163.779 1.00 76.28  ? 409 VAL C CG1 1 
ATOM   12425 C CG2 . VAL C 1 409 ? 155.643 158.636 162.089 1.00 70.40  ? 409 VAL C CG2 1 
ATOM   12426 N N   . VAL C 1 410 ? 152.146 161.581 163.563 1.00 72.91  ? 410 VAL C N   1 
ATOM   12427 C CA  . VAL C 1 410 ? 151.415 162.585 164.355 1.00 79.45  ? 410 VAL C CA  1 
ATOM   12428 C C   . VAL C 1 410 ? 149.983 162.162 164.687 1.00 83.70  ? 410 VAL C C   1 
ATOM   12429 O O   . VAL C 1 410 ? 149.451 162.603 165.697 1.00 88.03  ? 410 VAL C O   1 
ATOM   12430 C CB  . VAL C 1 410 ? 151.408 163.933 163.616 1.00 76.40  ? 410 VAL C CB  1 
ATOM   12431 C CG1 . VAL C 1 410 ? 150.530 165.009 164.259 1.00 80.44  ? 410 VAL C CG1 1 
ATOM   12432 C CG2 . VAL C 1 410 ? 152.819 164.515 163.542 1.00 74.72  ? 410 VAL C CG2 1 
ATOM   12433 N N   . ALA C 1 411 ? 149.328 161.328 163.872 1.00 80.78  ? 411 ALA C N   1 
ATOM   12434 C CA  . ALA C 1 411 ? 148.018 160.757 164.189 1.00 78.05  ? 411 ALA C CA  1 
ATOM   12435 C C   . ALA C 1 411 ? 148.134 159.574 165.170 1.00 86.76  ? 411 ALA C C   1 
ATOM   12436 O O   . ALA C 1 411 ? 147.426 159.512 166.177 1.00 90.52  ? 411 ALA C O   1 
ATOM   12437 C CB  . ALA C 1 411 ? 147.331 160.367 162.882 1.00 72.12  ? 411 ALA C CB  1 
ATOM   12438 N N   . TYR C 1 412 ? 149.087 158.670 164.939 1.00 88.66  ? 412 TYR C N   1 
ATOM   12439 C CA  . TYR C 1 412 ? 149.704 157.904 166.017 1.00 84.02  ? 412 TYR C CA  1 
ATOM   12440 C C   . TYR C 1 412 ? 150.486 158.895 166.912 1.00 90.25  ? 412 TYR C C   1 
ATOM   12441 O O   . TYR C 1 412 ? 150.813 159.991 166.473 1.00 93.36  ? 412 TYR C O   1 
ATOM   12442 C CB  . TYR C 1 412 ? 150.578 156.812 165.379 1.00 84.90  ? 412 TYR C CB  1 
ATOM   12443 C CG  . TYR C 1 412 ? 150.914 155.626 166.260 1.00 92.19  ? 412 TYR C CG  1 
ATOM   12444 C CD1 . TYR C 1 412 ? 152.025 155.680 167.111 1.00 93.54  ? 412 TYR C CD1 1 
ATOM   12445 C CD2 . TYR C 1 412 ? 150.157 154.445 166.181 1.00 91.17  ? 412 TYR C CD2 1 
ATOM   12446 C CE1 . TYR C 1 412 ? 152.386 154.566 167.886 1.00 92.13  ? 412 TYR C CE1 1 
ATOM   12447 C CE2 . TYR C 1 412 ? 150.518 153.320 166.948 1.00 89.83  ? 412 TYR C CE2 1 
ATOM   12448 C CZ  . TYR C 1 412 ? 151.643 153.377 167.795 1.00 93.93  ? 412 TYR C CZ  1 
ATOM   12449 O OH  . TYR C 1 412 ? 152.028 152.300 168.528 1.00 92.31  ? 412 TYR C OH  1 
ATOM   12450 N N   . HIS C 1 413 ? 150.773 158.585 168.173 1.00 97.67  ? 413 HIS C N   1 
ATOM   12451 C CA  . HIS C 1 413 ? 151.363 159.541 169.132 1.00 100.46 ? 413 HIS C CA  1 
ATOM   12452 C C   . HIS C 1 413 ? 150.536 160.816 169.432 1.00 100.85 ? 413 HIS C C   1 
ATOM   12453 O O   . HIS C 1 413 ? 151.073 161.762 170.007 1.00 102.82 ? 413 HIS C O   1 
ATOM   12454 C CB  . HIS C 1 413 ? 152.821 159.913 168.799 1.00 93.58  ? 413 HIS C CB  1 
ATOM   12455 C CG  . HIS C 1 413 ? 153.719 158.807 168.333 1.00 96.33  ? 413 HIS C CG  1 
ATOM   12456 N ND1 . HIS C 1 413 ? 154.226 158.690 167.065 1.00 98.91  ? 413 HIS C ND1 1 
ATOM   12457 C CD2 . HIS C 1 413 ? 154.297 157.827 169.088 1.00 99.33  ? 413 HIS C CD2 1 
ATOM   12458 C CE1 . HIS C 1 413 ? 155.092 157.668 167.043 1.00 100.32 ? 413 HIS C CE1 1 
ATOM   12459 N NE2 . HIS C 1 413 ? 155.166 157.102 168.259 1.00 100.91 ? 413 HIS C NE2 1 
ATOM   12460 N N   . GLN C 1 414 ? 149.229 160.857 169.139 1.00 99.43  ? 414 GLN C N   1 
ATOM   12461 C CA  . GLN C 1 414 ? 148.345 161.880 169.717 1.00 100.79 ? 414 GLN C CA  1 
ATOM   12462 C C   . GLN C 1 414 ? 148.286 161.744 171.252 1.00 109.94 ? 414 GLN C C   1 
ATOM   12463 O O   . GLN C 1 414 ? 148.293 160.618 171.764 1.00 107.66 ? 414 GLN C O   1 
ATOM   12464 C CB  . GLN C 1 414 ? 146.916 161.789 169.153 1.00 98.31  ? 414 GLN C CB  1 
ATOM   12465 C CG  . GLN C 1 414 ? 146.756 162.414 167.768 1.00 100.12 ? 414 GLN C CG  1 
ATOM   12466 C CD  . GLN C 1 414 ? 146.961 163.923 167.779 1.00 105.78 ? 414 GLN C CD  1 
ATOM   12467 O OE1 . GLN C 1 414 ? 146.180 164.679 168.331 1.00 107.67 ? 414 GLN C OE1 1 
ATOM   12468 N NE2 . GLN C 1 414 ? 148.011 164.412 167.178 1.00 104.06 ? 414 GLN C NE2 1 
ATOM   12469 N N   . PRO C 1 415 ? 148.192 162.854 172.005 1.00 121.57 ? 415 PRO C N   1 
ATOM   12470 C CA  . PRO C 1 415 ? 148.004 162.828 173.450 1.00 116.29 ? 415 PRO C CA  1 
ATOM   12471 C C   . PRO C 1 415 ? 146.573 162.415 173.831 1.00 116.14 ? 415 PRO C C   1 
ATOM   12472 O O   . PRO C 1 415 ? 145.663 162.426 173.000 1.00 112.02 ? 415 PRO C O   1 
ATOM   12473 C CB  . PRO C 1 415 ? 148.330 164.249 173.910 1.00 114.52 ? 415 PRO C CB  1 
ATOM   12474 C CG  . PRO C 1 415 ? 147.882 165.102 172.729 1.00 114.62 ? 415 PRO C CG  1 
ATOM   12475 C CD  . PRO C 1 415 ? 148.224 164.226 171.528 1.00 116.43 ? 415 PRO C CD  1 
ATOM   12476 N N   . SER C 1 416 ? 146.360 162.082 175.103 1.00 124.40 ? 416 SER C N   1 
ATOM   12477 C CA  . SER C 1 416 ? 145.027 161.818 175.661 1.00 126.27 ? 416 SER C CA  1 
ATOM   12478 C C   . SER C 1 416 ? 144.106 163.040 175.545 1.00 125.42 ? 416 SER C C   1 
ATOM   12479 O O   . SER C 1 416 ? 144.557 164.181 175.632 1.00 123.39 ? 416 SER C O   1 
ATOM   12480 C CB  . SER C 1 416 ? 145.128 161.398 177.127 1.00 125.23 ? 416 SER C CB  1 
ATOM   12481 O OG  . SER C 1 416 ? 146.025 160.311 177.267 1.00 122.52 ? 416 SER C OG  1 
ATOM   12482 N N   . LEU C 1 417 ? 142.806 162.818 175.363 1.00 125.30 ? 417 LEU C N   1 
ATOM   12483 C CA  . LEU C 1 417 ? 141.851 163.835 174.911 1.00 126.14 ? 417 LEU C CA  1 
ATOM   12484 C C   . LEU C 1 417 ? 140.513 163.669 175.636 1.00 123.13 ? 417 LEU C C   1 
ATOM   12485 O O   . LEU C 1 417 ? 139.846 164.655 175.967 1.00 120.08 ? 417 LEU C O   1 
ATOM   12486 C CB  . LEU C 1 417 ? 141.732 163.705 173.377 1.00 125.06 ? 417 LEU C CB  1 
ATOM   12487 C CG  . LEU C 1 417 ? 140.686 164.599 172.695 1.00 124.70 ? 417 LEU C CG  1 
ATOM   12488 C CD1 . LEU C 1 417 ? 141.030 166.072 172.867 1.00 122.84 ? 417 LEU C CD1 1 
ATOM   12489 C CD2 . LEU C 1 417 ? 140.626 164.257 171.207 1.00 120.43 ? 417 LEU C CD2 1 
ATOM   12490 N N   . PHE C 1 429 ? 161.204 167.162 174.559 1.00 127.92 ? 429 PHE C N   1 
ATOM   12491 C CA  . PHE C 1 429 ? 161.485 167.207 173.128 1.00 131.16 ? 429 PHE C CA  1 
ATOM   12492 C C   . PHE C 1 429 ? 160.343 166.605 172.296 1.00 132.75 ? 429 PHE C C   1 
ATOM   12493 O O   . PHE C 1 429 ? 159.976 167.141 171.251 1.00 130.26 ? 429 PHE C O   1 
ATOM   12494 C CB  . PHE C 1 429 ? 162.803 166.470 172.870 1.00 129.67 ? 429 PHE C CB  1 
ATOM   12495 C CG  . PHE C 1 429 ? 163.194 166.329 171.411 1.00 130.30 ? 429 PHE C CG  1 
ATOM   12496 C CD1 . PHE C 1 429 ? 163.642 167.446 170.690 1.00 129.80 ? 429 PHE C CD1 1 
ATOM   12497 C CD2 . PHE C 1 429 ? 163.141 165.073 170.783 1.00 131.03 ? 429 PHE C CD2 1 
ATOM   12498 C CE1 . PHE C 1 429 ? 164.037 167.307 169.350 1.00 130.68 ? 429 PHE C CE1 1 
ATOM   12499 C CE2 . PHE C 1 429 ? 163.545 164.934 169.445 1.00 131.18 ? 429 PHE C CE2 1 
ATOM   12500 C CZ  . PHE C 1 429 ? 163.995 166.048 168.728 1.00 131.08 ? 429 PHE C CZ  1 
ATOM   12501 N N   . GLY C 1 430 ? 159.720 165.528 172.776 1.00 130.45 ? 430 GLY C N   1 
ATOM   12502 C CA  . GLY C 1 430 ? 158.618 164.866 172.073 1.00 127.16 ? 430 GLY C CA  1 
ATOM   12503 C C   . GLY C 1 430 ? 157.406 165.779 171.850 1.00 129.67 ? 430 GLY C C   1 
ATOM   12504 O O   . GLY C 1 430 ? 156.781 165.721 170.794 1.00 131.89 ? 430 GLY C O   1 
ATOM   12505 N N   . GLU C 1 431 ? 157.101 166.671 172.791 1.00 126.26 ? 431 GLU C N   1 
ATOM   12506 C CA  . GLU C 1 431 ? 155.986 167.615 172.685 1.00 123.51 ? 431 GLU C CA  1 
ATOM   12507 C C   . GLU C 1 431 ? 156.229 168.740 171.669 1.00 126.03 ? 431 GLU C C   1 
ATOM   12508 O O   . GLU C 1 431 ? 155.313 169.104 170.931 1.00 125.58 ? 431 GLU C O   1 
ATOM   12509 C CB  . GLU C 1 431 ? 155.715 168.211 174.061 1.00 123.23 ? 431 GLU C CB  1 
ATOM   12510 N N   . SER C 1 432 ? 157.449 169.280 171.569 1.00 124.57 ? 432 SER C N   1 
ATOM   12511 C CA  . SER C 1 432 ? 157.771 170.293 170.552 1.00 124.71 ? 432 SER C CA  1 
ATOM   12512 C C   . SER C 1 432 ? 157.910 169.676 169.157 1.00 123.61 ? 432 SER C C   1 
ATOM   12513 O O   . SER C 1 432 ? 157.456 170.274 168.186 1.00 121.10 ? 432 SER C O   1 
ATOM   12514 C CB  . SER C 1 432 ? 159.015 171.097 170.930 1.00 124.59 ? 432 SER C CB  1 
ATOM   12515 O OG  . SER C 1 432 ? 160.167 170.289 170.978 1.00 126.04 ? 432 SER C OG  1 
ATOM   12516 N N   . MET C 1 433 ? 158.420 168.447 169.034 1.00 119.73 ? 433 MET C N   1 
ATOM   12517 C CA  . MET C 1 433 ? 158.380 167.698 167.771 1.00 117.77 ? 433 MET C CA  1 
ATOM   12518 C C   . MET C 1 433 ? 156.955 167.321 167.348 1.00 116.59 ? 433 MET C C   1 
ATOM   12519 O O   . MET C 1 433 ? 156.651 167.346 166.157 1.00 117.79 ? 433 MET C O   1 
ATOM   12520 C CB  . MET C 1 433 ? 159.253 166.443 167.860 1.00 118.17 ? 433 MET C CB  1 
ATOM   12521 C CG  . MET C 1 433 ? 160.742 166.789 167.946 1.00 122.27 ? 433 MET C CG  1 
ATOM   12522 S SD  . MET C 1 433 ? 161.423 167.723 166.546 1.00 128.14 ? 433 MET C SD  1 
ATOM   12523 C CE  . MET C 1 433 ? 161.323 166.469 165.249 1.00 118.10 ? 433 MET C CE  1 
ATOM   12524 N N   . LEU C 1 434 ? 156.046 167.032 168.281 1.00 111.55 ? 434 LEU C N   1 
ATOM   12525 C CA  . LEU C 1 434 ? 154.624 166.862 167.969 1.00 110.24 ? 434 LEU C CA  1 
ATOM   12526 C C   . LEU C 1 434 ? 154.007 168.170 167.459 1.00 112.54 ? 434 LEU C C   1 
ATOM   12527 O O   . LEU C 1 434 ? 153.295 168.153 166.457 1.00 115.42 ? 434 LEU C O   1 
ATOM   12528 C CB  . LEU C 1 434 ? 153.877 166.316 169.198 1.00 110.04 ? 434 LEU C CB  1 
ATOM   12529 C CG  . LEU C 1 434 ? 152.357 166.190 169.004 1.00 111.05 ? 434 LEU C CG  1 
ATOM   12530 C CD1 . LEU C 1 434 ? 152.004 165.146 167.951 1.00 110.75 ? 434 LEU C CD1 1 
ATOM   12531 C CD2 . LEU C 1 434 ? 151.685 165.801 170.314 1.00 112.38 ? 434 LEU C CD2 1 
ATOM   12532 N N   . LEU C 1 435 ? 154.293 169.313 168.094 1.00 110.77 ? 435 LEU C N   1 
ATOM   12533 C CA  . LEU C 1 435 ? 153.818 170.612 167.604 1.00 111.60 ? 435 LEU C CA  1 
ATOM   12534 C C   . LEU C 1 435 ? 154.355 170.931 166.198 1.00 108.60 ? 435 LEU C C   1 
ATOM   12535 O O   . LEU C 1 435 ? 153.582 171.328 165.329 1.00 106.05 ? 435 LEU C O   1 
ATOM   12536 C CB  . LEU C 1 435 ? 154.186 171.705 168.623 1.00 113.83 ? 435 LEU C CB  1 
ATOM   12537 C CG  . LEU C 1 435 ? 153.754 173.127 168.221 1.00 113.99 ? 435 LEU C CG  1 
ATOM   12538 C CD1 . LEU C 1 435 ? 152.239 173.242 168.053 1.00 109.57 ? 435 LEU C CD1 1 
ATOM   12539 C CD2 . LEU C 1 435 ? 154.200 174.105 169.304 1.00 109.92 ? 435 LEU C CD2 1 
ATOM   12540 N N   . LEU C 1 436 ? 155.648 170.700 165.939 1.00 101.39 ? 436 LEU C N   1 
ATOM   12541 C CA  . LEU C 1 436 ? 156.233 170.823 164.602 1.00 101.16 ? 436 LEU C CA  1 
ATOM   12542 C C   . LEU C 1 436 ? 155.487 169.940 163.596 1.00 105.16 ? 436 LEU C C   1 
ATOM   12543 O O   . LEU C 1 436 ? 155.107 170.417 162.534 1.00 106.75 ? 436 LEU C O   1 
ATOM   12544 C CB  . LEU C 1 436 ? 157.728 170.464 164.672 1.00 101.15 ? 436 LEU C CB  1 
ATOM   12545 C CG  . LEU C 1 436 ? 158.438 170.403 163.309 1.00 99.96  ? 436 LEU C CG  1 
ATOM   12546 C CD1 . LEU C 1 436 ? 158.462 171.763 162.621 1.00 102.06 ? 436 LEU C CD1 1 
ATOM   12547 C CD2 . LEU C 1 436 ? 159.869 169.931 163.500 1.00 98.01  ? 436 LEU C CD2 1 
ATOM   12548 N N   . GLY C 1 437 ? 155.215 168.682 163.943 1.00 97.04  ? 437 GLY C N   1 
ATOM   12549 C CA  . GLY C 1 437 ? 154.445 167.769 163.106 1.00 89.54  ? 437 GLY C CA  1 
ATOM   12550 C C   . GLY C 1 437 ? 153.060 168.312 162.753 1.00 92.60  ? 437 GLY C C   1 
ATOM   12551 O O   . GLY C 1 437 ? 152.670 168.267 161.590 1.00 102.82 ? 437 GLY C O   1 
ATOM   12552 N N   . HIS C 1 438 ? 152.336 168.897 163.706 1.00 92.79  ? 438 HIS C N   1 
ATOM   12553 C CA  . HIS C 1 438 ? 151.051 169.549 163.432 1.00 91.74  ? 438 HIS C CA  1 
ATOM   12554 C C   . HIS C 1 438 ? 151.173 170.750 162.489 1.00 97.22  ? 438 HIS C C   1 
ATOM   12555 O O   . HIS C 1 438 ? 150.336 170.912 161.604 1.00 99.10  ? 438 HIS C O   1 
ATOM   12556 C CB  . HIS C 1 438 ? 150.389 169.971 164.747 1.00 96.29  ? 438 HIS C CB  1 
ATOM   12557 C CG  . HIS C 1 438 ? 149.591 168.862 165.364 1.00 99.01  ? 438 HIS C CG  1 
ATOM   12558 N ND1 . HIS C 1 438 ? 148.378 168.409 164.909 1.00 100.22 ? 438 HIS C ND1 1 
ATOM   12559 C CD2 . HIS C 1 438 ? 149.950 168.072 166.417 1.00 97.99  ? 438 HIS C CD2 1 
ATOM   12560 C CE1 . HIS C 1 438 ? 148.002 167.379 165.681 1.00 97.76  ? 438 HIS C CE1 1 
ATOM   12561 N NE2 . HIS C 1 438 ? 148.926 167.144 166.623 1.00 98.42  ? 438 HIS C NE2 1 
ATOM   12562 N N   . ILE C 1 439 ? 152.210 171.578 162.625 1.00 102.72 ? 439 ILE C N   1 
ATOM   12563 C CA  . ILE C 1 439 ? 152.442 172.705 161.712 1.00 98.95  ? 439 ILE C CA  1 
ATOM   12564 C C   . ILE C 1 439 ? 152.819 172.214 160.308 1.00 95.88  ? 439 ILE C C   1 
ATOM   12565 O O   . ILE C 1 439 ? 152.257 172.698 159.331 1.00 98.40  ? 439 ILE C O   1 
ATOM   12566 C CB  . ILE C 1 439 ? 153.476 173.685 162.303 1.00 98.32  ? 439 ILE C CB  1 
ATOM   12567 C CG1 . ILE C 1 439 ? 152.977 174.338 163.610 1.00 99.75  ? 439 ILE C CG1 1 
ATOM   12568 C CG2 . ILE C 1 439 ? 153.863 174.776 161.299 1.00 94.53  ? 439 ILE C CG2 1 
ATOM   12569 C CD1 . ILE C 1 439 ? 151.662 175.104 163.529 1.00 95.58  ? 439 ILE C CD1 1 
ATOM   12570 N N   . LEU C 1 440 ? 153.688 171.213 160.168 1.00 84.91  ? 440 LEU C N   1 
ATOM   12571 C CA  . LEU C 1 440 ? 153.978 170.612 158.867 1.00 86.53  ? 440 LEU C CA  1 
ATOM   12572 C C   . LEU C 1 440 ? 152.735 169.996 158.212 1.00 87.07  ? 440 LEU C C   1 
ATOM   12573 O O   . LEU C 1 440 ? 152.557 170.136 157.009 1.00 93.38  ? 440 LEU C O   1 
ATOM   12574 C CB  . LEU C 1 440 ? 155.100 169.572 159.012 1.00 88.65  ? 440 LEU C CB  1 
ATOM   12575 C CG  . LEU C 1 440 ? 156.461 170.155 159.421 1.00 92.38  ? 440 LEU C CG  1 
ATOM   12576 C CD1 . LEU C 1 440 ? 157.454 169.020 159.647 1.00 89.27  ? 440 LEU C CD1 1 
ATOM   12577 C CD2 . LEU C 1 440 ? 157.034 171.081 158.357 1.00 90.98  ? 440 LEU C CD2 1 
ATOM   12578 N N   . ILE C 1 441 ? 151.834 169.372 158.973 1.00 77.31  ? 441 ILE C N   1 
ATOM   12579 C CA  . ILE C 1 441 ? 150.554 168.869 158.451 1.00 79.97  ? 441 ILE C CA  1 
ATOM   12580 C C   . ILE C 1 441 ? 149.623 170.013 158.051 1.00 85.35  ? 441 ILE C C   1 
ATOM   12581 O O   . ILE C 1 441 ? 148.990 169.922 157.006 1.00 92.07  ? 441 ILE C O   1 
ATOM   12582 C CB  . ILE C 1 441 ? 149.893 167.922 159.467 1.00 84.82  ? 441 ILE C CB  1 
ATOM   12583 C CG1 . ILE C 1 441 ? 150.697 166.615 159.520 1.00 84.98  ? 441 ILE C CG1 1 
ATOM   12584 C CG2 . ILE C 1 441 ? 148.431 167.597 159.135 1.00 85.37  ? 441 ILE C CG2 1 
ATOM   12585 C CD1 . ILE C 1 441 ? 150.411 165.822 160.787 1.00 90.96  ? 441 ILE C CD1 1 
ATOM   12586 N N   . LEU C 1 442 ? 149.549 171.105 158.814 1.00 78.79  ? 442 LEU C N   1 
ATOM   12587 C CA  . LEU C 1 442 ? 148.778 172.291 158.430 1.00 77.73  ? 442 LEU C CA  1 
ATOM   12588 C C   . LEU C 1 442 ? 149.298 172.880 157.111 1.00 82.34  ? 442 LEU C C   1 
ATOM   12589 O O   . LEU C 1 442 ? 148.518 173.120 156.198 1.00 82.72  ? 442 LEU C O   1 
ATOM   12590 C CB  . LEU C 1 442 ? 148.834 173.325 159.568 1.00 81.79  ? 442 LEU C CB  1 
ATOM   12591 C CG  . LEU C 1 442 ? 148.096 174.639 159.262 1.00 83.38  ? 442 LEU C CG  1 
ATOM   12592 C CD1 . LEU C 1 442 ? 146.590 174.452 159.215 1.00 79.60  ? 442 LEU C CD1 1 
ATOM   12593 C CD2 . LEU C 1 442 ? 148.426 175.670 160.330 1.00 80.70  ? 442 LEU C CD2 1 
ATOM   12594 N N   . LEU C 1 443 ? 150.610 173.081 156.984 1.00 88.96  ? 443 LEU C N   1 
ATOM   12595 C CA  . LEU C 1 443 ? 151.230 173.628 155.778 1.00 81.90  ? 443 LEU C CA  1 
ATOM   12596 C C   . LEU C 1 443 ? 151.104 172.692 154.573 1.00 80.39  ? 443 LEU C C   1 
ATOM   12597 O O   . LEU C 1 443 ? 150.748 173.153 153.497 1.00 87.10  ? 443 LEU C O   1 
ATOM   12598 C CB  . LEU C 1 443 ? 152.703 173.965 156.045 1.00 81.91  ? 443 LEU C CB  1 
ATOM   12599 C CG  . LEU C 1 443 ? 152.935 175.104 157.049 1.00 86.02  ? 443 LEU C CG  1 
ATOM   12600 C CD1 . LEU C 1 443 ? 154.436 175.315 157.207 1.00 84.20  ? 443 LEU C CD1 1 
ATOM   12601 C CD2 . LEU C 1 443 ? 152.304 176.424 156.611 1.00 83.01  ? 443 LEU C CD2 1 
ATOM   12602 N N   . GLY C 1 444 ? 151.309 171.383 154.731 1.00 69.94  ? 444 GLY C N   1 
ATOM   12603 C CA  . GLY C 1 444 ? 151.040 170.405 153.675 1.00 72.89  ? 444 GLY C CA  1 
ATOM   12604 C C   . GLY C 1 444 ? 149.561 170.333 153.284 1.00 73.53  ? 444 GLY C C   1 
ATOM   12605 O O   . GLY C 1 444 ? 149.240 170.196 152.109 1.00 81.71  ? 444 GLY C O   1 
ATOM   12606 N N   . GLY C 1 445 ? 148.644 170.510 154.236 1.00 71.25  ? 445 GLY C N   1 
ATOM   12607 C CA  . GLY C 1 445 ? 147.209 170.563 153.982 1.00 68.09  ? 445 GLY C CA  1 
ATOM   12608 C C   . GLY C 1 445 ? 146.772 171.835 153.268 1.00 71.66  ? 445 GLY C C   1 
ATOM   12609 O O   . GLY C 1 445 ? 146.017 171.753 152.310 1.00 82.65  ? 445 GLY C O   1 
ATOM   12610 N N   . ILE C 1 446 ? 147.300 173.005 153.634 1.00 74.69  ? 446 ILE C N   1 
ATOM   12611 C CA  . ILE C 1 446 ? 147.073 174.258 152.901 1.00 71.63  ? 446 ILE C CA  1 
ATOM   12612 C C   . ILE C 1 446 ? 147.705 174.192 151.508 1.00 78.33  ? 446 ILE C C   1 
ATOM   12613 O O   . ILE C 1 446 ? 147.053 174.559 150.539 1.00 82.97  ? 446 ILE C O   1 
ATOM   12614 C CB  . ILE C 1 446 ? 147.595 175.466 153.708 1.00 75.36  ? 446 ILE C CB  1 
ATOM   12615 C CG1 . ILE C 1 446 ? 146.699 175.699 154.941 1.00 80.31  ? 446 ILE C CG1 1 
ATOM   12616 C CG2 . ILE C 1 446 ? 147.649 176.746 152.856 1.00 74.32  ? 446 ILE C CG2 1 
ATOM   12617 C CD1 . ILE C 1 446 ? 147.275 176.705 155.943 1.00 77.39  ? 446 ILE C CD1 1 
ATOM   12618 N N   . TYR C 1 447 ? 148.932 173.687 151.367 1.00 76.24  ? 447 TYR C N   1 
ATOM   12619 C CA  . TYR C 1 447 ? 149.575 173.532 150.064 1.00 66.08  ? 447 TYR C CA  1 
ATOM   12620 C C   . TYR C 1 447 ? 148.737 172.680 149.111 1.00 71.03  ? 447 TYR C C   1 
ATOM   12621 O O   . TYR C 1 447 ? 148.464 173.101 147.992 1.00 82.24  ? 447 TYR C O   1 
ATOM   12622 C CB  . TYR C 1 447 ? 150.972 172.931 150.241 1.00 68.44  ? 447 TYR C CB  1 
ATOM   12623 C CG  . TYR C 1 447 ? 151.694 172.751 148.927 1.00 76.93  ? 447 TYR C CG  1 
ATOM   12624 C CD1 . TYR C 1 447 ? 151.456 171.611 148.138 1.00 78.63  ? 447 TYR C CD1 1 
ATOM   12625 C CD2 . TYR C 1 447 ? 152.534 173.770 148.452 1.00 76.57  ? 447 TYR C CD2 1 
ATOM   12626 C CE1 . TYR C 1 447 ? 152.002 171.514 146.846 1.00 72.39  ? 447 TYR C CE1 1 
ATOM   12627 C CE2 . TYR C 1 447 ? 153.096 173.669 147.172 1.00 79.34  ? 447 TYR C CE2 1 
ATOM   12628 C CZ  . TYR C 1 447 ? 152.808 172.558 146.354 1.00 79.94  ? 447 TYR C CZ  1 
ATOM   12629 O OH  . TYR C 1 447 ? 153.286 172.503 145.087 1.00 86.69  ? 447 TYR C OH  1 
ATOM   12630 N N   . LEU C 1 448 ? 148.288 171.499 149.547 1.00 65.29  ? 448 LEU C N   1 
ATOM   12631 C CA  . LEU C 1 448 ? 147.419 170.638 148.751 1.00 60.17  ? 448 LEU C CA  1 
ATOM   12632 C C   . LEU C 1 448 ? 146.036 171.256 148.527 1.00 65.26  ? 448 LEU C C   1 
ATOM   12633 O O   . LEU C 1 448 ? 145.505 171.116 147.430 1.00 78.23  ? 448 LEU C O   1 
ATOM   12634 C CB  . LEU C 1 448 ? 147.293 169.266 149.426 1.00 70.71  ? 448 LEU C CB  1 
ATOM   12635 C CG  . LEU C 1 448 ? 148.574 168.419 149.394 1.00 67.39  ? 448 LEU C CG  1 
ATOM   12636 C CD1 . LEU C 1 448 ? 148.407 167.226 150.322 1.00 70.87  ? 448 LEU C CD1 1 
ATOM   12637 C CD2 . LEU C 1 448 ? 148.862 167.879 147.997 1.00 70.72  ? 448 LEU C CD2 1 
ATOM   12638 N N   . LEU C 1 449 ? 145.460 171.974 149.499 1.00 68.74  ? 449 LEU C N   1 
ATOM   12639 C CA  . LEU C 1 449 ? 144.189 172.674 149.296 1.00 67.55  ? 449 LEU C CA  1 
ATOM   12640 C C   . LEU C 1 449 ? 144.331 173.733 148.208 1.00 74.26  ? 449 LEU C C   1 
ATOM   12641 O O   . LEU C 1 449 ? 143.528 173.766 147.277 1.00 75.08  ? 449 LEU C O   1 
ATOM   12642 C CB  . LEU C 1 449 ? 143.710 173.280 150.626 1.00 71.52  ? 449 LEU C CB  1 
ATOM   12643 C CG  . LEU C 1 449 ? 142.417 174.098 150.539 1.00 74.06  ? 449 LEU C CG  1 
ATOM   12644 C CD1 . LEU C 1 449 ? 141.267 173.272 149.992 1.00 74.40  ? 449 LEU C CD1 1 
ATOM   12645 C CD2 . LEU C 1 449 ? 142.025 174.584 151.925 1.00 72.98  ? 449 LEU C CD2 1 
ATOM   12646 N N   . LEU C 1 450 ? 145.381 174.562 148.213 1.00 79.71  ? 450 LEU C N   1 
ATOM   12647 C CA  . LEU C 1 450 ? 145.633 175.554 147.158 1.00 74.41  ? 450 LEU C CA  1 
ATOM   12648 C C   . LEU C 1 450 ? 145.943 174.922 145.794 1.00 74.77  ? 450 LEU C C   1 
ATOM   12649 O O   . LEU C 1 450 ? 145.411 175.364 144.782 1.00 78.02  ? 450 LEU C O   1 
ATOM   12650 C CB  . LEU C 1 450 ? 146.779 176.487 147.573 1.00 73.59  ? 450 LEU C CB  1 
ATOM   12651 C CG  . LEU C 1 450 ? 146.457 177.408 148.753 1.00 76.25  ? 450 LEU C CG  1 
ATOM   12652 C CD1 . LEU C 1 450 ? 147.685 178.249 149.076 1.00 74.01  ? 450 LEU C CD1 1 
ATOM   12653 C CD2 . LEU C 1 450 ? 145.296 178.352 148.459 1.00 72.64  ? 450 LEU C CD2 1 
ATOM   12654 N N   . GLY C 1 451 ? 146.751 173.865 145.748 1.00 77.34  ? 451 GLY C N   1 
ATOM   12655 C CA  . GLY C 1 451 ? 147.043 173.136 144.516 1.00 69.98  ? 451 GLY C CA  1 
ATOM   12656 C C   . GLY C 1 451 ? 145.806 172.524 143.854 1.00 70.93  ? 451 GLY C C   1 
ATOM   12657 O O   . GLY C 1 451 ? 145.668 172.610 142.634 1.00 78.23  ? 451 GLY C O   1 
ATOM   12658 N N   . GLN C 1 452 ? 144.867 171.957 144.618 1.00 73.99  ? 452 GLN C N   1 
ATOM   12659 C CA  . GLN C 1 452 ? 143.628 171.421 144.047 1.00 74.64  ? 452 GLN C CA  1 
ATOM   12660 C C   . GLN C 1 452 ? 142.582 172.493 143.724 1.00 71.10  ? 452 GLN C C   1 
ATOM   12661 O O   . GLN C 1 452 ? 141.869 172.358 142.734 1.00 80.57  ? 452 GLN C O   1 
ATOM   12662 C CB  . GLN C 1 452 ? 143.022 170.361 144.970 1.00 71.00  ? 452 GLN C CB  1 
ATOM   12663 C CG  . GLN C 1 452 ? 143.893 169.113 145.135 1.00 68.84  ? 452 GLN C CG  1 
ATOM   12664 C CD  . GLN C 1 452 ? 144.283 168.449 143.823 1.00 75.09  ? 452 GLN C CD  1 
ATOM   12665 O OE1 . GLN C 1 452 ? 145.449 168.344 143.485 1.00 80.89  ? 452 GLN C OE1 1 
ATOM   12666 N NE2 . GLN C 1 452 ? 143.352 167.989 143.024 1.00 71.97  ? 452 GLN C NE2 1 
ATOM   12667 N N   . LEU C 1 453 ? 142.492 173.585 144.484 1.00 68.67  ? 453 LEU C N   1 
ATOM   12668 C CA  . LEU C 1 453 ? 141.642 174.711 144.083 1.00 73.51  ? 453 LEU C CA  1 
ATOM   12669 C C   . LEU C 1 453 ? 142.158 175.368 142.794 1.00 75.71  ? 453 LEU C C   1 
ATOM   12670 O O   . LEU C 1 453 ? 141.355 175.736 141.943 1.00 80.49  ? 453 LEU C O   1 
ATOM   12671 C CB  . LEU C 1 453 ? 141.525 175.729 145.225 1.00 77.27  ? 453 LEU C CB  1 
ATOM   12672 C CG  . LEU C 1 453 ? 140.692 175.243 146.426 1.00 78.39  ? 453 LEU C CG  1 
ATOM   12673 C CD1 . LEU C 1 453 ? 140.800 176.257 147.554 1.00 71.75  ? 453 LEU C CD1 1 
ATOM   12674 C CD2 . LEU C 1 453 ? 139.217 175.089 146.085 1.00 73.75  ? 453 LEU C CD2 1 
ATOM   12675 N N   . TRP C 1 454 ? 143.474 175.443 142.579 1.00 86.82  ? 454 TRP C N   1 
ATOM   12676 C CA  . TRP C 1 454 ? 144.039 175.873 141.298 1.00 81.58  ? 454 TRP C CA  1 
ATOM   12677 C C   . TRP C 1 454 ? 143.686 174.915 140.154 1.00 81.50  ? 454 TRP C C   1 
ATOM   12678 O O   . TRP C 1 454 ? 143.281 175.379 139.096 1.00 92.75  ? 454 TRP C O   1 
ATOM   12679 C CB  . TRP C 1 454 ? 145.551 176.047 141.430 1.00 82.21  ? 454 TRP C CB  1 
ATOM   12680 C CG  . TRP C 1 454 ? 146.245 176.644 140.246 1.00 88.16  ? 454 TRP C CG  1 
ATOM   12681 C CD1 . TRP C 1 454 ? 145.973 177.854 139.711 1.00 88.62  ? 454 TRP C CD1 1 
ATOM   12682 C CD2 . TRP C 1 454 ? 147.359 176.109 139.467 1.00 92.71  ? 454 TRP C CD2 1 
ATOM   12683 N NE1 . TRP C 1 454 ? 146.834 178.104 138.663 1.00 86.52  ? 454 TRP C NE1 1 
ATOM   12684 C CE2 . TRP C 1 454 ? 147.732 177.078 138.492 1.00 89.18  ? 454 TRP C CE2 1 
ATOM   12685 C CE3 . TRP C 1 454 ? 148.109 174.913 139.498 1.00 90.47  ? 454 TRP C CE3 1 
ATOM   12686 C CZ2 . TRP C 1 454 ? 148.804 176.885 137.611 1.00 88.34  ? 454 TRP C CZ2 1 
ATOM   12687 C CZ3 . TRP C 1 454 ? 149.181 174.704 138.607 1.00 89.71  ? 454 TRP C CZ3 1 
ATOM   12688 C CH2 . TRP C 1 454 ? 149.537 175.690 137.673 1.00 91.21  ? 454 TRP C CH2 1 
ATOM   12689 N N   . TYR C 1 455 ? 143.738 173.594 140.357 1.00 75.95  ? 455 TYR C N   1 
ATOM   12690 C CA  . TYR C 1 455 ? 143.285 172.619 139.356 1.00 73.95  ? 455 TYR C CA  1 
ATOM   12691 C C   . TYR C 1 455 ? 141.832 172.848 138.941 1.00 81.50  ? 455 TYR C C   1 
ATOM   12692 O O   . TYR C 1 455 ? 141.549 173.025 137.758 1.00 90.87  ? 455 TYR C O   1 
ATOM   12693 C CB  . TYR C 1 455 ? 143.484 171.186 139.858 1.00 78.80  ? 455 TYR C CB  1 
ATOM   12694 C CG  . TYR C 1 455 ? 143.001 170.128 138.886 1.00 83.25  ? 455 TYR C CG  1 
ATOM   12695 C CD1 . TYR C 1 455 ? 143.820 169.747 137.813 1.00 83.54  ? 455 TYR C CD1 1 
ATOM   12696 C CD2 . TYR C 1 455 ? 141.730 169.544 139.028 1.00 83.11  ? 455 TYR C CD2 1 
ATOM   12697 C CE1 . TYR C 1 455 ? 143.379 168.789 136.885 1.00 82.29  ? 455 TYR C CE1 1 
ATOM   12698 C CE2 . TYR C 1 455 ? 141.276 168.593 138.096 1.00 88.26  ? 455 TYR C CE2 1 
ATOM   12699 C CZ  . TYR C 1 455 ? 142.106 168.209 137.022 1.00 89.72  ? 455 TYR C CZ  1 
ATOM   12700 O OH  . TYR C 1 455 ? 141.698 167.283 136.120 1.00 88.48  ? 455 TYR C OH  1 
ATOM   12701 N N   . PHE C 1 456 ? 140.893 172.921 139.884 1.00 84.30  ? 456 PHE C N   1 
ATOM   12702 C CA  . PHE C 1 456 ? 139.488 173.154 139.547 1.00 82.51  ? 456 PHE C CA  1 
ATOM   12703 C C   . PHE C 1 456 ? 139.202 174.567 139.037 1.00 86.95  ? 456 PHE C C   1 
ATOM   12704 O O   . PHE C 1 456 ? 138.276 174.739 138.255 1.00 93.64  ? 456 PHE C O   1 
ATOM   12705 C CB  . PHE C 1 456 ? 138.598 172.788 140.729 1.00 77.34  ? 456 PHE C CB  1 
ATOM   12706 C CG  . PHE C 1 456 ? 138.606 171.303 141.025 1.00 83.67  ? 456 PHE C CG  1 
ATOM   12707 C CD1 . PHE C 1 456 ? 138.152 170.399 140.049 1.00 85.47  ? 456 PHE C CD1 1 
ATOM   12708 C CD2 . PHE C 1 456 ? 139.089 170.822 142.250 1.00 80.73  ? 456 PHE C CD2 1 
ATOM   12709 C CE1 . PHE C 1 456 ? 138.176 169.019 140.297 1.00 85.99  ? 456 PHE C CE1 1 
ATOM   12710 C CE2 . PHE C 1 456 ? 139.114 169.442 142.499 1.00 80.57  ? 456 PHE C CE2 1 
ATOM   12711 C CZ  . PHE C 1 456 ? 138.650 168.545 141.527 1.00 85.08  ? 456 PHE C CZ  1 
ATOM   12712 N N   . TRP C 1 457 ? 140.008 175.570 139.381 1.00 88.82  ? 457 TRP C N   1 
ATOM   12713 C CA  . TRP C 1 457 ? 139.926 176.887 138.749 1.00 85.95  ? 457 TRP C CA  1 
ATOM   12714 C C   . TRP C 1 457 ? 140.358 176.850 137.279 1.00 90.31  ? 457 TRP C C   1 
ATOM   12715 O O   . TRP C 1 457 ? 139.650 177.369 136.419 1.00 92.35  ? 457 TRP C O   1 
ATOM   12716 C CB  . TRP C 1 457 ? 140.764 177.897 139.531 1.00 87.83  ? 457 TRP C CB  1 
ATOM   12717 C CG  . TRP C 1 457 ? 140.841 179.240 138.888 1.00 92.15  ? 457 TRP C CG  1 
ATOM   12718 C CD1 . TRP C 1 457 ? 141.950 179.800 138.359 1.00 91.96  ? 457 TRP C CD1 1 
ATOM   12719 C CD2 . TRP C 1 457 ? 139.762 180.192 138.655 1.00 95.33  ? 457 TRP C CD2 1 
ATOM   12720 N NE1 . TRP C 1 457 ? 141.632 181.023 137.810 1.00 94.31  ? 457 TRP C NE1 1 
ATOM   12721 C CE2 . TRP C 1 457 ? 140.292 181.310 137.953 1.00 95.48  ? 457 TRP C CE2 1 
ATOM   12722 C CE3 . TRP C 1 457 ? 138.384 180.217 138.958 1.00 93.13  ? 457 TRP C CE3 1 
ATOM   12723 C CZ2 . TRP C 1 457 ? 139.493 182.390 137.555 1.00 93.18  ? 457 TRP C CZ2 1 
ATOM   12724 C CZ3 . TRP C 1 457 ? 137.576 181.296 138.564 1.00 92.66  ? 457 TRP C CZ3 1 
ATOM   12725 C CH2 . TRP C 1 457 ? 138.124 182.378 137.859 1.00 93.28  ? 457 TRP C CH2 1 
ATOM   12726 N N   . ARG C 1 458 ? 141.458 176.151 136.977 1.00 84.24  ? 458 ARG C N   1 
ATOM   12727 C CA  . ARG C 1 458 ? 141.945 176.032 135.570 1.00 83.51  ? 458 ARG C CA  1 
ATOM   12728 C C   . ARG C 1 458 ? 140.971 175.208 134.725 1.00 87.63  ? 458 ARG C C   1 
ATOM   12729 O O   . ARG C 1 458 ? 140.782 175.554 133.544 1.00 88.55  ? 458 ARG C O   1 
ATOM   12730 C CB  . ARG C 1 458 ? 143.337 175.388 135.550 1.00 80.25  ? 458 ARG C CB  1 
ATOM   12731 C CG  . ARG C 1 458 ? 144.427 176.384 135.954 1.00 78.39  ? 458 ARG C CG  1 
ATOM   12732 C CD  . ARG C 1 458 ? 145.825 175.856 135.631 1.00 81.57  ? 458 ARG C CD  1 
ATOM   12733 N NE  . ARG C 1 458 ? 146.274 174.817 136.574 1.00 86.68  ? 458 ARG C NE  1 
ATOM   12734 C CZ  . ARG C 1 458 ? 146.002 173.522 136.458 1.00 85.29  ? 458 ARG C CZ  1 
ATOM   12735 N NH1 . ARG C 1 458 ? 146.451 172.669 137.363 1.00 83.47  ? 458 ARG C NH1 1 
ATOM   12736 N NH2 . ARG C 1 458 ? 145.281 173.084 135.441 1.00 82.90  ? 458 ARG C NH2 1 
ATOM   12737 N N   . ARG C 1 459 ? 140.385 174.170 135.304 1.00 87.39  ? 459 ARG C N   1 
ATOM   12738 C CA  . ARG C 1 459 ? 139.454 173.236 134.644 1.00 91.00  ? 459 ARG C CA  1 
ATOM   12739 C C   . ARG C 1 459 ? 137.971 173.643 134.695 1.00 97.61  ? 459 ARG C C   1 
ATOM   12740 O O   . ARG C 1 459 ? 137.115 172.897 134.233 1.00 99.31  ? 459 ARG C O   1 
ATOM   12741 C CB  . ARG C 1 459 ? 139.712 171.826 135.202 1.00 89.14  ? 459 ARG C CB  1 
ATOM   12742 C CG  . ARG C 1 459 ? 141.155 171.315 134.994 1.00 89.40  ? 459 ARG C CG  1 
ATOM   12743 C CD  . ARG C 1 459 ? 141.578 171.192 133.527 1.00 87.51  ? 459 ARG C CD  1 
ATOM   12744 N NE  . ARG C 1 459 ? 143.040 171.062 133.387 1.00 91.41  ? 459 ARG C NE  1 
ATOM   12745 C CZ  . ARG C 1 459 ? 143.780 171.517 132.391 1.00 96.08  ? 459 ARG C CZ  1 
ATOM   12746 N NH1 . ARG C 1 459 ? 145.064 171.337 132.405 1.00 89.26  ? 459 ARG C NH1 1 
ATOM   12747 N NH2 . ARG C 1 459 ? 143.275 172.164 131.381 1.00 93.80  ? 459 ARG C NH2 1 
ATOM   12748 N N   . ARG C 1 460 ? 137.696 174.845 135.236 1.00 106.31 ? 460 ARG C N   1 
ATOM   12749 C CA  . ARG C 1 460 ? 136.323 175.409 135.462 1.00 104.45 ? 460 ARG C CA  1 
ATOM   12750 C C   . ARG C 1 460 ? 135.323 175.173 134.323 1.00 105.98 ? 460 ARG C C   1 
ATOM   12751 O O   . ARG C 1 460 ? 134.198 174.732 134.629 1.00 105.26 ? 460 ARG C O   1 
ATOM   12752 C CB  . ARG C 1 460 ? 136.560 176.887 135.786 1.00 100.75 ? 460 ARG C CB  1 
ATOM   12753 C CG  . ARG C 1 460 ? 135.326 177.716 136.136 1.00 101.96 ? 460 ARG C CG  1 
ATOM   12754 C CD  . ARG C 1 460 ? 135.761 179.139 136.502 1.00 103.99 ? 460 ARG C CD  1 
ATOM   12755 N NE  . ARG C 1 460 ? 136.081 179.957 135.318 1.00 104.96 ? 460 ARG C NE  1 
ATOM   12756 C CZ  . ARG C 1 460 ? 137.308 180.138 134.843 1.00 103.30 ? 460 ARG C CZ  1 
ATOM   12757 N NH1 . ARG C 1 460 ? 137.500 180.890 133.773 1.00 101.34 ? 460 ARG C NH1 1 
ATOM   12758 N NH2 . ARG C 1 460 ? 138.340 179.572 135.444 1.00 100.69 ? 460 ARG C NH2 1 
ATOM   12759 N N   . LEU C 1 461 ? 135.696 175.441 133.077 1.00 103.82 ? 461 LEU C N   1 
ATOM   12760 C CA  . LEU C 1 461 ? 134.779 175.374 131.927 1.00 105.55 ? 461 LEU C CA  1 
ATOM   12761 C C   . LEU C 1 461 ? 134.317 173.945 131.584 1.00 105.51 ? 461 LEU C C   1 
ATOM   12762 O O   . LEU C 1 461 ? 133.271 173.769 130.960 1.00 100.63 ? 461 LEU C O   1 
ATOM   12763 C CB  . LEU C 1 461 ? 135.439 176.031 130.704 1.00 105.57 ? 461 LEU C CB  1 
ATOM   12764 C CG  . LEU C 1 461 ? 135.831 177.510 130.877 1.00 106.68 ? 461 LEU C CG  1 
ATOM   12765 C CD1 . LEU C 1 461 ? 136.410 178.039 129.572 1.00 102.12 ? 461 LEU C CD1 1 
ATOM   12766 C CD2 . LEU C 1 461 ? 134.653 178.397 131.261 1.00 106.34 ? 461 LEU C CD2 1 
ATOM   12767 N N   . PHE C 1 462 ? 135.099 172.936 131.966 1.00 105.49 ? 462 PHE C N   1 
ATOM   12768 C CA  . PHE C 1 462 ? 134.897 171.523 131.631 1.00 104.20 ? 462 PHE C CA  1 
ATOM   12769 C C   . PHE C 1 462 ? 135.076 170.668 132.890 1.00 102.01 ? 462 PHE C C   1 
ATOM   12770 O O   . PHE C 1 462 ? 135.741 169.629 132.883 1.00 102.33 ? 462 PHE C O   1 
ATOM   12771 C CB  . PHE C 1 462 ? 135.830 171.121 130.478 1.00 100.36 ? 462 PHE C CB  1 
ATOM   12772 C CG  . PHE C 1 462 ? 135.614 171.908 129.201 1.00 101.27 ? 462 PHE C CG  1 
ATOM   12773 C CD1 . PHE C 1 462 ? 134.551 171.581 128.343 1.00 99.05  ? 462 PHE C CD1 1 
ATOM   12774 C CD2 . PHE C 1 462 ? 136.433 173.009 128.901 1.00 103.01 ? 462 PHE C CD2 1 
ATOM   12775 C CE1 . PHE C 1 462 ? 134.294 172.362 127.205 1.00 100.28 ? 462 PHE C CE1 1 
ATOM   12776 C CE2 . PHE C 1 462 ? 136.177 173.794 127.766 1.00 105.40 ? 462 PHE C CE2 1 
ATOM   12777 C CZ  . PHE C 1 462 ? 135.101 173.474 126.923 1.00 102.49 ? 462 PHE C CZ  1 
ATOM   12778 N N   . ILE C 1 463 ? 134.540 171.150 134.008 1.00 106.69 ? 463 ILE C N   1 
ATOM   12779 C CA  . ILE C 1 463 ? 134.926 170.683 135.340 1.00 111.86 ? 463 ILE C CA  1 
ATOM   12780 C C   . ILE C 1 463 ? 134.556 169.212 135.569 1.00 114.75 ? 463 ILE C C   1 
ATOM   12781 O O   . ILE C 1 463 ? 135.398 168.442 136.020 1.00 112.69 ? 463 ILE C O   1 
ATOM   12782 C CB  . ILE C 1 463 ? 134.390 171.662 136.402 1.00 110.98 ? 463 ILE C CB  1 
ATOM   12783 C CG1 . ILE C 1 463 ? 135.064 171.400 137.758 1.00 110.93 ? 463 ILE C CG1 1 
ATOM   12784 C CG2 . ILE C 1 463 ? 132.860 171.636 136.525 1.00 110.68 ? 463 ILE C CG2 1 
ATOM   12785 C CD1 . ILE C 1 463 ? 134.788 172.477 138.803 1.00 109.15 ? 463 ILE C CD1 1 
ATOM   12786 N N   . TRP C 1 464 ? 133.368 168.780 135.134 1.00 113.54 ? 464 TRP C N   1 
ATOM   12787 C CA  . TRP C 1 464 ? 132.942 167.380 135.197 1.00 111.95 ? 464 TRP C CA  1 
ATOM   12788 C C   . TRP C 1 464 ? 133.804 166.461 134.328 1.00 112.02 ? 464 TRP C C   1 
ATOM   12789 O O   . TRP C 1 464 ? 134.225 165.391 134.765 1.00 112.46 ? 464 TRP C O   1 
ATOM   12790 C CB  . TRP C 1 464 ? 131.485 167.294 134.755 1.00 108.39 ? 464 TRP C CB  1 
ATOM   12791 N N   . ILE C 1 465 ? 134.162 166.897 133.118 1.00 106.82 ? 465 ILE C N   1 
ATOM   12792 C CA  . ILE C 1 465 ? 135.086 166.175 132.224 1.00 107.23 ? 465 ILE C CA  1 
ATOM   12793 C C   . ILE C 1 465 ? 136.470 166.030 132.871 1.00 104.67 ? 465 ILE C C   1 
ATOM   12794 O O   . ILE C 1 465 ? 137.141 165.014 132.739 1.00 107.47 ? 465 ILE C O   1 
ATOM   12795 C CB  . ILE C 1 465 ? 135.200 166.866 130.846 1.00 105.94 ? 465 ILE C CB  1 
ATOM   12796 C CG1 . ILE C 1 465 ? 133.812 167.188 130.256 1.00 102.54 ? 465 ILE C CG1 1 
ATOM   12797 C CG2 . ILE C 1 465 ? 136.012 165.979 129.899 1.00 100.67 ? 465 ILE C CG2 1 
ATOM   12798 C CD1 . ILE C 1 465 ? 133.862 167.819 128.867 1.00 102.05 ? 465 ILE C CD1 1 
ATOM   12799 N N   . SER C 1 466 ? 136.874 167.031 133.641 1.00 106.16 ? 466 SER C N   1 
ATOM   12800 C CA  . SER C 1 466 ? 138.149 167.053 134.351 1.00 112.64 ? 466 SER C CA  1 
ATOM   12801 C C   . SER C 1 466 ? 138.152 166.275 135.679 1.00 114.22 ? 466 SER C C   1 
ATOM   12802 O O   . SER C 1 466 ? 139.169 166.292 136.372 1.00 114.79 ? 466 SER C O   1 
ATOM   12803 C CB  . SER C 1 466 ? 138.577 168.504 134.538 1.00 111.27 ? 466 SER C CB  1 
ATOM   12804 O OG  . SER C 1 466 ? 138.596 169.143 133.274 1.00 111.10 ? 466 SER C OG  1 
ATOM   12805 N N   . PHE C 1 467 ? 137.071 165.564 136.039 1.00 115.98 ? 467 PHE C N   1 
ATOM   12806 C CA  . PHE C 1 467 ? 137.061 164.616 137.162 1.00 116.11 ? 467 PHE C CA  1 
ATOM   12807 C C   . PHE C 1 467 ? 136.338 163.279 136.904 1.00 116.59 ? 467 PHE C C   1 
ATOM   12808 O O   . PHE C 1 467 ? 136.464 162.377 137.725 1.00 117.59 ? 467 PHE C O   1 
ATOM   12809 C CB  . PHE C 1 467 ? 136.573 165.299 138.451 1.00 113.79 ? 467 PHE C CB  1 
ATOM   12810 C CG  . PHE C 1 467 ? 135.130 165.781 138.511 1.00 115.52 ? 467 PHE C CG  1 
ATOM   12811 C CD1 . PHE C 1 467 ? 134.056 164.870 138.484 1.00 114.44 ? 467 PHE C CD1 1 
ATOM   12812 C CD2 . PHE C 1 467 ? 134.858 167.145 138.730 1.00 114.61 ? 467 PHE C CD2 1 
ATOM   12813 C CE1 . PHE C 1 467 ? 132.740 165.316 138.669 1.00 115.95 ? 467 PHE C CE1 1 
ATOM   12814 C CE2 . PHE C 1 467 ? 133.542 167.589 138.931 1.00 113.31 ? 467 PHE C CE2 1 
ATOM   12815 C CZ  . PHE C 1 467 ? 132.478 166.676 138.901 1.00 114.49 ? 467 PHE C CZ  1 
ATOM   12816 N N   . MET C 1 468 ? 135.604 163.102 135.798 1.00 113.30 ? 468 MET C N   1 
ATOM   12817 C CA  . MET C 1 468 ? 134.794 161.894 135.541 1.00 113.33 ? 468 MET C CA  1 
ATOM   12818 C C   . MET C 1 468 ? 135.587 160.579 135.625 1.00 113.27 ? 468 MET C C   1 
ATOM   12819 O O   . MET C 1 468 ? 135.150 159.630 136.271 1.00 110.54 ? 468 MET C O   1 
ATOM   12820 C CB  . MET C 1 468 ? 134.065 162.007 134.186 1.00 113.12 ? 468 MET C CB  1 
ATOM   12821 C CG  . MET C 1 468 ? 134.956 162.433 133.008 1.00 112.44 ? 468 MET C CG  1 
ATOM   12822 S SD  . MET C 1 468 ? 134.222 162.406 131.346 1.00 118.64 ? 468 MET C SD  1 
ATOM   12823 C CE  . MET C 1 468 ? 132.659 163.294 131.592 1.00 110.66 ? 468 MET C CE  1 
ATOM   12824 N N   . ASP C 1 469 ? 136.775 160.535 135.020 1.00 106.55 ? 469 ASP C N   1 
ATOM   12825 C CA  . ASP C 1 469 ? 137.754 159.451 135.180 1.00 103.84 ? 469 ASP C CA  1 
ATOM   12826 C C   . ASP C 1 469 ? 138.777 159.752 136.290 1.00 102.04 ? 469 ASP C C   1 
ATOM   12827 O O   . ASP C 1 469 ? 139.263 158.850 136.964 1.00 102.81 ? 469 ASP C O   1 
ATOM   12828 C CB  . ASP C 1 469 ? 138.471 159.218 133.841 1.00 102.41 ? 469 ASP C CB  1 
ATOM   12829 C CG  . ASP C 1 469 ? 139.148 160.449 133.213 1.00 101.15 ? 469 ASP C CG  1 
ATOM   12830 O OD1 . ASP C 1 469 ? 139.222 161.526 133.848 1.00 101.33 ? 469 ASP C OD1 1 
ATOM   12831 O OD2 . ASP C 1 469 ? 139.597 160.323 132.057 1.00 101.95 ? 469 ASP C OD2 1 
ATOM   12832 N N   . SER C 1 470 ? 139.094 161.029 136.479 1.00 89.84  ? 470 SER C N   1 
ATOM   12833 C CA  . SER C 1 470 ? 140.135 161.567 137.344 1.00 86.55  ? 470 SER C CA  1 
ATOM   12834 C C   . SER C 1 470 ? 139.600 161.861 138.745 1.00 87.84  ? 470 SER C C   1 
ATOM   12835 O O   . SER C 1 470 ? 139.724 162.969 139.266 1.00 86.90  ? 470 SER C O   1 
ATOM   12836 C CB  . SER C 1 470 ? 140.749 162.796 136.669 1.00 89.15  ? 470 SER C CB  1 
ATOM   12837 O OG  . SER C 1 470 ? 141.249 162.447 135.390 1.00 96.00  ? 470 SER C OG  1 
ATOM   12838 N N   . TYR C 1 471 ? 138.992 160.857 139.375 1.00 78.52  ? 471 TYR C N   1 
ATOM   12839 C CA  . TYR C 1 471 ? 138.367 160.971 140.692 1.00 63.54  ? 471 TYR C CA  1 
ATOM   12840 C C   . TYR C 1 471 ? 139.339 161.337 141.819 1.00 61.30  ? 471 TYR C C   1 
ATOM   12841 O O   . TYR C 1 471 ? 138.932 161.971 142.789 1.00 65.75  ? 471 TYR C O   1 
ATOM   12842 C CB  . TYR C 1 471 ? 137.614 159.677 141.005 1.00 68.23  ? 471 TYR C CB  1 
ATOM   12843 C CG  . TYR C 1 471 ? 138.457 158.427 141.181 1.00 75.56  ? 471 TYR C CG  1 
ATOM   12844 C CD1 . TYR C 1 471 ? 138.977 158.107 142.449 1.00 72.53  ? 471 TYR C CD1 1 
ATOM   12845 C CD2 . TYR C 1 471 ? 138.653 157.536 140.108 1.00 73.72  ? 471 TYR C CD2 1 
ATOM   12846 C CE1 . TYR C 1 471 ? 139.645 156.886 142.658 1.00 73.74  ? 471 TYR C CE1 1 
ATOM   12847 C CE2 . TYR C 1 471 ? 139.346 156.325 140.303 1.00 72.45  ? 471 TYR C CE2 1 
ATOM   12848 C CZ  . TYR C 1 471 ? 139.820 155.987 141.585 1.00 77.60  ? 471 TYR C CZ  1 
ATOM   12849 O OH  . TYR C 1 471 ? 140.432 154.795 141.806 1.00 71.10  ? 471 TYR C OH  1 
ATOM   12850 N N   . PHE C 1 472 ? 140.633 161.038 141.696 1.00 62.58  ? 472 PHE C N   1 
ATOM   12851 C CA  . PHE C 1 472 ? 141.640 161.464 142.669 1.00 57.22  ? 472 PHE C CA  1 
ATOM   12852 C C   . PHE C 1 472 ? 141.738 162.984 142.804 1.00 62.26  ? 472 PHE C C   1 
ATOM   12853 O O   . PHE C 1 472 ? 142.076 163.465 143.875 1.00 74.38  ? 472 PHE C O   1 
ATOM   12854 C CB  . PHE C 1 472 ? 143.012 160.889 142.323 1.00 52.47  ? 472 PHE C CB  1 
ATOM   12855 C CG  . PHE C 1 472 ? 143.163 159.412 142.598 1.00 59.78  ? 472 PHE C CG  1 
ATOM   12856 C CD1 . PHE C 1 472 ? 143.382 158.971 143.910 1.00 57.98  ? 472 PHE C CD1 1 
ATOM   12857 C CD2 . PHE C 1 472 ? 143.114 158.484 141.547 1.00 62.03  ? 472 PHE C CD2 1 
ATOM   12858 C CE1 . PHE C 1 472 ? 143.543 157.602 144.173 1.00 54.08  ? 472 PHE C CE1 1 
ATOM   12859 C CE2 . PHE C 1 472 ? 143.295 157.118 141.808 1.00 61.32  ? 472 PHE C CE2 1 
ATOM   12860 C CZ  . PHE C 1 472 ? 143.509 156.678 143.120 1.00 56.01  ? 472 PHE C CZ  1 
ATOM   12861 N N   . GLU C 1 473 ? 141.402 163.778 141.792 1.00 74.94  ? 473 GLU C N   1 
ATOM   12862 C CA  . GLU C 1 473 ? 141.485 165.237 141.926 1.00 70.37  ? 473 GLU C CA  1 
ATOM   12863 C C   . GLU C 1 473 ? 140.467 165.790 142.936 1.00 75.39  ? 473 GLU C C   1 
ATOM   12864 O O   . GLU C 1 473 ? 140.726 166.810 143.574 1.00 80.03  ? 473 GLU C O   1 
ATOM   12865 C CB  . GLU C 1 473 ? 141.362 165.901 140.544 1.00 74.11  ? 473 GLU C CB  1 
ATOM   12866 C CG  . GLU C 1 473 ? 142.426 165.426 139.536 1.00 79.50  ? 473 GLU C CG  1 
ATOM   12867 C CD  . GLU C 1 473 ? 143.867 165.495 140.069 1.00 88.41  ? 473 GLU C CD  1 
ATOM   12868 O OE1 . GLU C 1 473 ? 144.219 166.426 140.829 1.00 90.00  ? 473 GLU C OE1 1 
ATOM   12869 O OE2 . GLU C 1 473 ? 144.674 164.581 139.776 1.00 86.46  ? 473 GLU C OE2 1 
ATOM   12870 N N   . ILE C 1 474 ? 139.349 165.085 143.150 1.00 69.67  ? 474 ILE C N   1 
ATOM   12871 C CA  . ILE C 1 474 ? 138.381 165.344 144.223 1.00 61.40  ? 474 ILE C CA  1 
ATOM   12872 C C   . ILE C 1 474 ? 138.890 164.805 145.563 1.00 68.67  ? 474 ILE C C   1 
ATOM   12873 O O   . ILE C 1 474 ? 138.801 165.493 146.574 1.00 71.68  ? 474 ILE C O   1 
ATOM   12874 C CB  . ILE C 1 474 ? 137.014 164.717 143.877 1.00 67.07  ? 474 ILE C CB  1 
ATOM   12875 C CG1 . ILE C 1 474 ? 136.433 165.297 142.575 1.00 68.54  ? 474 ILE C CG1 1 
ATOM   12876 C CG2 . ILE C 1 474 ? 136.020 164.916 145.031 1.00 68.27  ? 474 ILE C CG2 1 
ATOM   12877 C CD1 . ILE C 1 474 ? 135.256 164.493 142.041 1.00 67.05  ? 474 ILE C CD1 1 
ATOM   12878 N N   . LEU C 1 475 ? 139.438 163.584 145.603 1.00 63.79  ? 475 LEU C N   1 
ATOM   12879 C CA  . LEU C 1 475 ? 139.916 162.957 146.838 1.00 57.95  ? 475 LEU C CA  1 
ATOM   12880 C C   . LEU C 1 475 ? 141.134 163.656 147.451 1.00 58.64  ? 475 LEU C C   1 
ATOM   12881 O O   . LEU C 1 475 ? 141.272 163.692 148.670 1.00 75.08  ? 475 LEU C O   1 
ATOM   12882 C CB  . LEU C 1 475 ? 140.239 161.478 146.602 1.00 52.18  ? 475 LEU C CB  1 
ATOM   12883 C CG  . LEU C 1 475 ? 139.101 160.593 146.084 1.00 53.83  ? 475 LEU C CG  1 
ATOM   12884 C CD1 . LEU C 1 475 ? 139.620 159.167 145.949 1.00 61.18  ? 475 LEU C CD1 1 
ATOM   12885 C CD2 . LEU C 1 475 ? 137.898 160.582 147.017 1.00 62.21  ? 475 LEU C CD2 1 
ATOM   12886 N N   . PHE C 1 476 ? 142.006 164.263 146.651 1.00 43.86  ? 476 PHE C N   1 
ATOM   12887 C CA  . PHE C 1 476 ? 143.062 165.144 147.146 1.00 47.58  ? 476 PHE C CA  1 
ATOM   12888 C C   . PHE C 1 476 ? 142.503 166.474 147.693 1.00 55.39  ? 476 PHE C C   1 
ATOM   12889 O O   . PHE C 1 476 ? 143.107 167.049 148.592 1.00 56.75  ? 476 PHE C O   1 
ATOM   12890 C CB  . PHE C 1 476 ? 144.111 165.364 146.047 1.00 50.15  ? 476 PHE C CB  1 
ATOM   12891 C CG  . PHE C 1 476 ? 145.225 164.329 145.985 1.00 52.49  ? 476 PHE C CG  1 
ATOM   12892 C CD1 . PHE C 1 476 ? 145.048 163.101 145.329 1.00 61.16  ? 476 PHE C CD1 1 
ATOM   12893 C CD2 . PHE C 1 476 ? 146.479 164.619 146.546 1.00 57.65  ? 476 PHE C CD2 1 
ATOM   12894 C CE1 . PHE C 1 476 ? 146.107 162.189 145.216 1.00 59.08  ? 476 PHE C CE1 1 
ATOM   12895 C CE2 . PHE C 1 476 ? 147.543 163.709 146.434 1.00 54.90  ? 476 PHE C CE2 1 
ATOM   12896 C CZ  . PHE C 1 476 ? 147.357 162.497 145.765 1.00 44.60  ? 476 PHE C CZ  1 
ATOM   12897 N N   . LEU C 1 477 ? 141.412 167.001 147.130 1.00 63.51  ? 477 LEU C N   1 
ATOM   12898 C CA  . LEU C 1 477 ? 140.787 168.232 147.613 1.00 62.57  ? 477 LEU C CA  1 
ATOM   12899 C C   . LEU C 1 477 ? 140.083 167.962 148.937 1.00 68.00  ? 477 LEU C C   1 
ATOM   12900 O O   . LEU C 1 477 ? 140.246 168.710 149.893 1.00 75.20  ? 477 LEU C O   1 
ATOM   12901 C CB  . LEU C 1 477 ? 139.812 168.782 146.555 1.00 65.39  ? 477 LEU C CB  1 
ATOM   12902 C CG  . LEU C 1 477 ? 139.046 170.040 146.998 1.00 63.61  ? 477 LEU C CG  1 
ATOM   12903 C CD1 . LEU C 1 477 ? 139.966 171.239 147.158 1.00 69.22  ? 477 LEU C CD1 1 
ATOM   12904 C CD2 . LEU C 1 477 ? 137.976 170.408 145.980 1.00 67.88  ? 477 LEU C CD2 1 
ATOM   12905 N N   . LEU C 1 478 ? 139.368 166.845 149.021 1.00 68.90  ? 478 LEU C N   1 
ATOM   12906 C CA  . LEU C 1 478 ? 138.710 166.370 150.224 1.00 63.58  ? 478 LEU C CA  1 
ATOM   12907 C C   . LEU C 1 478 ? 139.716 166.080 151.346 1.00 66.04  ? 478 LEU C C   1 
ATOM   12908 O O   . LEU C 1 478 ? 139.538 166.567 152.456 1.00 73.97  ? 478 LEU C O   1 
ATOM   12909 C CB  . LEU C 1 478 ? 137.869 165.149 149.830 1.00 61.06  ? 478 LEU C CB  1 
ATOM   12910 C CG  . LEU C 1 478 ? 137.049 164.542 150.969 1.00 70.78  ? 478 LEU C CG  1 
ATOM   12911 C CD1 . LEU C 1 478 ? 136.017 165.519 151.518 1.00 67.47  ? 478 LEU C CD1 1 
ATOM   12912 C CD2 . LEU C 1 478 ? 136.335 163.300 150.450 1.00 66.46  ? 478 LEU C CD2 1 
ATOM   12913 N N   . GLN C 1 479 ? 140.813 165.365 151.083 1.00 61.27  ? 479 GLN C N   1 
ATOM   12914 C CA  . GLN C 1 479 ? 141.849 165.131 152.097 1.00 60.88  ? 479 GLN C CA  1 
ATOM   12915 C C   . GLN C 1 479 ? 142.473 166.438 152.595 1.00 65.39  ? 479 GLN C C   1 
ATOM   12916 O O   . GLN C 1 479 ? 142.693 166.598 153.794 1.00 69.90  ? 479 GLN C O   1 
ATOM   12917 C CB  . GLN C 1 479 ? 142.918 164.187 151.539 1.00 59.59  ? 479 GLN C CB  1 
ATOM   12918 C CG  . GLN C 1 479 ? 143.783 163.521 152.615 1.00 59.32  ? 479 GLN C CG  1 
ATOM   12919 C CD  . GLN C 1 479 ? 145.041 164.254 153.084 1.00 65.46  ? 479 GLN C CD  1 
ATOM   12920 O OE1 . GLN C 1 479 ? 145.464 165.270 152.565 1.00 66.75  ? 479 GLN C OE1 1 
ATOM   12921 N NE2 . GLN C 1 479 ? 145.694 163.735 154.094 1.00 70.64  ? 479 GLN C NE2 1 
ATOM   12922 N N   . ALA C 1 480 ? 142.704 167.404 151.710 1.00 76.74  ? 480 ALA C N   1 
ATOM   12923 C CA  . ALA C 1 480 ? 143.240 168.704 152.072 1.00 69.31  ? 480 ALA C CA  1 
ATOM   12924 C C   . ALA C 1 480 ? 142.239 169.549 152.876 1.00 74.78  ? 480 ALA C C   1 
ATOM   12925 O O   . ALA C 1 480 ? 142.613 170.109 153.904 1.00 78.14  ? 480 ALA C O   1 
ATOM   12926 C CB  . ALA C 1 480 ? 143.670 169.403 150.793 1.00 70.98  ? 480 ALA C CB  1 
ATOM   12927 N N   . LEU C 1 481 ? 140.958 169.590 152.490 1.00 71.76  ? 481 LEU C N   1 
ATOM   12928 C CA  . LEU C 1 481 ? 139.909 170.255 153.269 1.00 72.24  ? 481 LEU C CA  1 
ATOM   12929 C C   . LEU C 1 481 ? 139.808 169.667 154.676 1.00 76.52  ? 481 LEU C C   1 
ATOM   12930 O O   . LEU C 1 481 ? 139.838 170.411 155.649 1.00 79.03  ? 481 LEU C O   1 
ATOM   12931 C CB  . LEU C 1 481 ? 138.547 170.137 152.563 1.00 73.51  ? 481 LEU C CB  1 
ATOM   12932 C CG  . LEU C 1 481 ? 138.332 171.116 151.402 1.00 82.94  ? 481 LEU C CG  1 
ATOM   12933 C CD1 . LEU C 1 481 ? 137.045 170.762 150.666 1.00 76.30  ? 481 LEU C CD1 1 
ATOM   12934 C CD2 . LEU C 1 481 ? 138.196 172.553 151.892 1.00 77.92  ? 481 LEU C CD2 1 
ATOM   12935 N N   . LEU C 1 482 ? 139.738 168.343 154.805 1.00 76.55  ? 482 LEU C N   1 
ATOM   12936 C CA  . LEU C 1 482 ? 139.657 167.660 156.096 1.00 72.27  ? 482 LEU C CA  1 
ATOM   12937 C C   . LEU C 1 482 ? 140.935 167.809 156.933 1.00 64.27  ? 482 LEU C C   1 
ATOM   12938 O O   . LEU C 1 482 ? 140.871 167.836 158.159 1.00 72.04  ? 482 LEU C O   1 
ATOM   12939 C CB  . LEU C 1 482 ? 139.360 166.183 155.839 1.00 71.58  ? 482 LEU C CB  1 
ATOM   12940 C CG  . LEU C 1 482 ? 137.982 165.890 155.235 1.00 67.91  ? 482 LEU C CG  1 
ATOM   12941 C CD1 . LEU C 1 482 ? 137.979 164.440 154.774 1.00 70.06  ? 482 LEU C CD1 1 
ATOM   12942 C CD2 . LEU C 1 482 ? 136.871 166.071 156.261 1.00 70.13  ? 482 LEU C CD2 1 
ATOM   12943 N N   . THR C 1 483 ? 142.099 167.961 156.308 1.00 68.00  ? 483 THR C N   1 
ATOM   12944 C CA  . THR C 1 483 ? 143.341 168.294 157.013 1.00 72.39  ? 483 THR C CA  1 
ATOM   12945 C C   . THR C 1 483 ? 143.300 169.714 157.573 1.00 73.24  ? 483 THR C C   1 
ATOM   12946 O O   . THR C 1 483 ? 143.613 169.927 158.734 1.00 75.21  ? 483 THR C O   1 
ATOM   12947 C CB  . THR C 1 483 ? 144.559 168.127 156.101 1.00 80.53  ? 483 THR C CB  1 
ATOM   12948 O OG1 . THR C 1 483 ? 144.614 166.798 155.664 1.00 80.48  ? 483 THR C OG1 1 
ATOM   12949 C CG2 . THR C 1 483 ? 145.865 168.423 156.822 1.00 71.64  ? 483 THR C CG2 1 
ATOM   12950 N N   . VAL C 1 484 ? 142.853 170.703 156.799 1.00 82.75  ? 484 VAL C N   1 
ATOM   12951 C CA  . VAL C 1 484 ? 142.707 172.076 157.300 1.00 81.58  ? 484 VAL C CA  1 
ATOM   12952 C C   . VAL C 1 484 ? 141.606 172.164 158.363 1.00 83.07  ? 484 VAL C C   1 
ATOM   12953 O O   . VAL C 1 484 ? 141.844 172.706 159.437 1.00 86.93  ? 484 VAL C O   1 
ATOM   12954 C CB  . VAL C 1 484 ? 142.489 173.061 156.138 1.00 86.26  ? 484 VAL C CB  1 
ATOM   12955 C CG1 . VAL C 1 484 ? 142.244 174.485 156.631 1.00 86.75  ? 484 VAL C CG1 1 
ATOM   12956 C CG2 . VAL C 1 484 ? 143.730 173.096 155.247 1.00 82.75  ? 484 VAL C CG2 1 
ATOM   12957 N N   . LEU C 1 485 ? 140.435 171.564 158.141 1.00 80.61  ? 485 LEU C N   1 
ATOM   12958 C CA  . LEU C 1 485 ? 139.356 171.507 159.129 1.00 80.94  ? 485 LEU C CA  1 
ATOM   12959 C C   . LEU C 1 485 ? 139.799 170.838 160.431 1.00 85.82  ? 485 LEU C C   1 
ATOM   12960 O O   . LEU C 1 485 ? 139.525 171.373 161.498 1.00 86.24  ? 485 LEU C O   1 
ATOM   12961 C CB  . LEU C 1 485 ? 138.143 170.756 158.557 1.00 84.50  ? 485 LEU C CB  1 
ATOM   12962 C CG  . LEU C 1 485 ? 137.356 171.542 157.502 1.00 90.64  ? 485 LEU C CG  1 
ATOM   12963 C CD1 . LEU C 1 485 ? 136.424 170.602 156.745 1.00 88.55  ? 485 LEU C CD1 1 
ATOM   12964 C CD2 . LEU C 1 485 ? 136.508 172.629 158.156 1.00 87.71  ? 485 LEU C CD2 1 
ATOM   12965 N N   . SER C 1 486 ? 140.498 169.703 160.391 1.00 86.92  ? 486 SER C N   1 
ATOM   12966 C CA  . SER C 1 486 ? 140.952 169.042 161.620 1.00 76.72  ? 486 SER C CA  1 
ATOM   12967 C C   . SER C 1 486 ? 141.968 169.884 162.390 1.00 78.28  ? 486 SER C C   1 
ATOM   12968 O O   . SER C 1 486 ? 141.842 169.997 163.602 1.00 90.53  ? 486 SER C O   1 
ATOM   12969 C CB  . SER C 1 486 ? 141.491 167.638 161.349 1.00 76.02  ? 486 SER C CB  1 
ATOM   12970 O OG  . SER C 1 486 ? 142.499 167.640 160.374 1.00 86.59  ? 486 SER C OG  1 
ATOM   12971 N N   . GLN C 1 487 ? 142.916 170.567 161.746 1.00 83.93  ? 487 GLN C N   1 
ATOM   12972 C CA  . GLN C 1 487 ? 143.784 171.489 162.485 1.00 85.26  ? 487 GLN C CA  1 
ATOM   12973 C C   . GLN C 1 487 ? 143.013 172.709 163.026 1.00 85.82  ? 487 GLN C C   1 
ATOM   12974 O O   . GLN C 1 487 ? 143.265 173.126 164.149 1.00 88.76  ? 487 GLN C O   1 
ATOM   12975 C CB  . GLN C 1 487 ? 144.989 171.911 161.637 1.00 88.33  ? 487 GLN C CB  1 
ATOM   12976 C CG  . GLN C 1 487 ? 145.879 170.753 161.164 1.00 86.78  ? 487 GLN C CG  1 
ATOM   12977 C CD  . GLN C 1 487 ? 146.295 169.770 162.248 1.00 89.38  ? 487 GLN C CD  1 
ATOM   12978 O OE1 . GLN C 1 487 ? 146.643 170.120 163.364 1.00 91.01  ? 487 GLN C OE1 1 
ATOM   12979 N NE2 . GLN C 1 487 ? 146.287 168.493 161.959 1.00 89.29  ? 487 GLN C NE2 1 
ATOM   12980 N N   . VAL C 1 488 ? 142.015 173.234 162.307 1.00 91.75  ? 488 VAL C N   1 
ATOM   12981 C CA  . VAL C 1 488 ? 141.122 174.296 162.804 1.00 93.52  ? 488 VAL C CA  1 
ATOM   12982 C C   . VAL C 1 488 ? 140.328 173.842 164.029 1.00 96.00  ? 488 VAL C C   1 
ATOM   12983 O O   . VAL C 1 488 ? 140.332 174.534 165.043 1.00 93.73  ? 488 VAL C O   1 
ATOM   12984 C CB  . VAL C 1 488 ? 140.208 174.808 161.676 1.00 93.22  ? 488 VAL C CB  1 
ATOM   12985 C CG1 . VAL C 1 488 ? 139.033 175.652 162.166 1.00 92.26  ? 488 VAL C CG1 1 
ATOM   12986 C CG2 . VAL C 1 488 ? 141.018 175.668 160.706 1.00 90.89  ? 488 VAL C CG2 1 
ATOM   12987 N N   . LEU C 1 489 ? 139.706 172.662 164.006 1.00 93.65  ? 489 LEU C N   1 
ATOM   12988 C CA  . LEU C 1 489 ? 139.019 172.107 165.172 1.00 87.51  ? 489 LEU C CA  1 
ATOM   12989 C C   . LEU C 1 489 ? 139.983 171.828 166.335 1.00 84.41  ? 489 LEU C C   1 
ATOM   12990 O O   . LEU C 1 489 ? 139.598 171.990 167.490 1.00 88.63  ? 489 LEU C O   1 
ATOM   12991 C CB  . LEU C 1 489 ? 138.245 170.834 164.794 1.00 89.70  ? 489 LEU C CB  1 
ATOM   12992 C CG  . LEU C 1 489 ? 137.062 171.005 163.827 1.00 88.76  ? 489 LEU C CG  1 
ATOM   12993 C CD1 . LEU C 1 489 ? 136.165 169.779 163.933 1.00 89.65  ? 489 LEU C CD1 1 
ATOM   12994 C CD2 . LEU C 1 489 ? 136.194 172.223 164.110 1.00 89.80  ? 489 LEU C CD2 1 
ATOM   12995 N N   . ARG C 1 490 ? 141.240 171.462 166.068 1.00 92.32  ? 490 ARG C N   1 
ATOM   12996 C CA  . ARG C 1 490 ? 142.266 171.297 167.108 1.00 95.76  ? 490 ARG C CA  1 
ATOM   12997 C C   . ARG C 1 490 ? 142.688 172.629 167.733 1.00 98.36  ? 490 ARG C C   1 
ATOM   12998 O O   . ARG C 1 490 ? 142.847 172.693 168.946 1.00 98.32  ? 490 ARG C O   1 
ATOM   12999 C CB  . ARG C 1 490 ? 143.471 170.545 166.536 1.00 91.66  ? 490 ARG C CB  1 
ATOM   13000 C CG  . ARG C 1 490 ? 144.388 170.009 167.633 1.00 93.05  ? 490 ARG C CG  1 
ATOM   13001 C CD  . ARG C 1 490 ? 145.675 169.443 167.044 1.00 96.95  ? 490 ARG C CD  1 
ATOM   13002 N NE  . ARG C 1 490 ? 146.568 170.519 166.569 1.00 102.94 ? 490 ARG C NE  1 
ATOM   13003 C CZ  . ARG C 1 490 ? 147.451 171.190 167.288 1.00 100.46 ? 490 ARG C CZ  1 
ATOM   13004 N NH1 . ARG C 1 490 ? 148.139 172.152 166.752 1.00 97.88  ? 490 ARG C NH1 1 
ATOM   13005 N NH2 . ARG C 1 490 ? 147.662 170.934 168.544 1.00 95.76  ? 490 ARG C NH2 1 
ATOM   13006 N N   . PHE C 1 491 ? 142.805 173.710 166.961 1.00 107.25 ? 491 PHE C N   1 
ATOM   13007 C CA  . PHE C 1 491 ? 142.998 175.063 167.505 1.00 102.87 ? 491 PHE C CA  1 
ATOM   13008 C C   . PHE C 1 491 ? 141.774 175.557 168.297 1.00 105.29 ? 491 PHE C C   1 
ATOM   13009 O O   . PHE C 1 491 ? 141.934 176.212 169.324 1.00 104.73 ? 491 PHE C O   1 
ATOM   13010 C CB  . PHE C 1 491 ? 143.346 176.046 166.377 1.00 99.98  ? 491 PHE C CB  1 
ATOM   13011 N N   . MET C 1 492 ? 140.556 175.182 167.897 1.00 109.59 ? 492 MET C N   1 
ATOM   13012 C CA  . MET C 1 492 ? 139.333 175.361 168.698 1.00 108.71 ? 492 MET C CA  1 
ATOM   13013 C C   . MET C 1 492 ? 139.249 174.429 169.925 1.00 108.22 ? 492 MET C C   1 
ATOM   13014 O O   . MET C 1 492 ? 138.352 174.575 170.750 1.00 105.26 ? 492 MET C O   1 
ATOM   13015 C CB  . MET C 1 492 ? 138.096 175.145 167.810 1.00 109.49 ? 492 MET C CB  1 
ATOM   13016 C CG  . MET C 1 492 ? 137.924 176.217 166.733 1.00 110.54 ? 492 MET C CG  1 
ATOM   13017 S SD  . MET C 1 492 ? 136.707 175.798 165.453 1.00 118.38 ? 492 MET C SD  1 
ATOM   13018 C CE  . MET C 1 492 ? 135.208 175.575 166.440 1.00 108.24 ? 492 MET C CE  1 
ATOM   13019 N N   . GLU C 1 493 ? 140.153 173.459 170.049 1.00 107.86 ? 493 GLU C N   1 
ATOM   13020 C CA  . GLU C 1 493 ? 140.188 172.430 171.091 1.00 106.51 ? 493 GLU C CA  1 
ATOM   13021 C C   . GLU C 1 493 ? 138.943 171.531 171.198 1.00 107.51 ? 493 GLU C C   1 
ATOM   13022 O O   . GLU C 1 493 ? 138.778 170.838 172.200 1.00 104.24 ? 493 GLU C O   1 
ATOM   13023 C CB  . GLU C 1 493 ? 140.574 173.061 172.428 1.00 102.15 ? 493 GLU C CB  1 
ATOM   13024 N N   . THR C 1 494 ? 138.063 171.501 170.188 1.00 107.39 ? 494 THR C N   1 
ATOM   13025 C CA  . THR C 1 494 ? 136.910 170.582 170.173 1.00 105.79 ? 494 THR C CA  1 
ATOM   13026 C C   . THR C 1 494 ? 137.342 169.172 169.778 1.00 104.04 ? 494 THR C C   1 
ATOM   13027 O O   . THR C 1 494 ? 138.056 168.972 168.798 1.00 104.39 ? 494 THR C O   1 
ATOM   13028 C CB  . THR C 1 494 ? 135.748 171.087 169.305 1.00 103.90 ? 494 THR C CB  1 
ATOM   13029 O OG1 . THR C 1 494 ? 134.671 170.181 169.378 1.00 100.79 ? 494 THR C OG1 1 
ATOM   13030 C CG2 . THR C 1 494 ? 136.055 171.238 167.825 1.00 103.17 ? 494 THR C CG2 1 
ATOM   13031 N N   . GLU C 1 495 ? 136.920 168.164 170.536 1.00 105.44 ? 495 GLU C N   1 
ATOM   13032 C CA  . GLU C 1 495 ? 137.431 166.793 170.417 1.00 106.45 ? 495 GLU C CA  1 
ATOM   13033 C C   . GLU C 1 495 ? 137.039 166.097 169.104 1.00 107.61 ? 495 GLU C C   1 
ATOM   13034 O O   . GLU C 1 495 ? 137.679 165.130 168.698 1.00 109.11 ? 495 GLU C O   1 
ATOM   13035 C CB  . GLU C 1 495 ? 136.996 165.972 171.639 1.00 102.70 ? 495 GLU C CB  1 
ATOM   13036 N N   . TRP C 1 496 ? 136.055 166.637 168.381 1.00 99.76  ? 496 TRP C N   1 
ATOM   13037 C CA  . TRP C 1 496 ? 135.727 166.241 167.009 1.00 97.49  ? 496 TRP C CA  1 
ATOM   13038 C C   . TRP C 1 496 ? 136.844 166.517 165.991 1.00 99.32  ? 496 TRP C C   1 
ATOM   13039 O O   . TRP C 1 496 ? 136.739 166.072 164.850 1.00 96.98  ? 496 TRP C O   1 
ATOM   13040 C CB  . TRP C 1 496 ? 134.411 166.900 166.589 1.00 94.98  ? 496 TRP C CB  1 
ATOM   13041 C CG  . TRP C 1 496 ? 133.205 166.285 167.226 1.00 103.23 ? 496 TRP C CG  1 
ATOM   13042 C CD1 . TRP C 1 496 ? 132.543 166.761 168.301 1.00 100.44 ? 496 TRP C CD1 1 
ATOM   13043 C CD2 . TRP C 1 496 ? 132.531 165.041 166.859 1.00 109.18 ? 496 TRP C CD2 1 
ATOM   13044 N NE1 . TRP C 1 496 ? 131.520 165.897 168.635 1.00 99.22  ? 496 TRP C NE1 1 
ATOM   13045 C CE2 . TRP C 1 496 ? 131.474 164.812 167.787 1.00 103.51 ? 496 TRP C CE2 1 
ATOM   13046 C CE3 . TRP C 1 496 ? 132.698 164.090 165.831 1.00 105.22 ? 496 TRP C CE3 1 
ATOM   13047 C CZ2 . TRP C 1 496 ? 130.650 163.683 167.718 1.00 98.13  ? 496 TRP C CZ2 1 
ATOM   13048 C CZ3 . TRP C 1 496 ? 131.874 162.951 165.750 1.00 99.23  ? 496 TRP C CZ3 1 
ATOM   13049 C CH2 . TRP C 1 496 ? 130.856 162.743 166.694 1.00 97.38  ? 496 TRP C CH2 1 
ATOM   13050 N N   . TYR C 1 497 ? 137.947 167.175 166.367 1.00 94.58  ? 497 TYR C N   1 
ATOM   13051 C CA  . TYR C 1 497 ? 139.131 167.228 165.511 1.00 90.36  ? 497 TYR C CA  1 
ATOM   13052 C C   . TYR C 1 497 ? 139.696 165.834 165.226 1.00 92.98  ? 497 TYR C C   1 
ATOM   13053 O O   . TYR C 1 497 ? 140.164 165.600 164.113 1.00 100.88 ? 497 TYR C O   1 
ATOM   13054 C CB  . TYR C 1 497 ? 140.215 168.135 166.110 1.00 89.65  ? 497 TYR C CB  1 
ATOM   13055 C CG  . TYR C 1 497 ? 141.236 167.457 167.000 1.00 90.64  ? 497 TYR C CG  1 
ATOM   13056 C CD1 . TYR C 1 497 ? 142.340 166.789 166.434 1.00 85.98  ? 497 TYR C CD1 1 
ATOM   13057 C CD2 . TYR C 1 497 ? 141.083 167.491 168.394 1.00 93.44  ? 497 TYR C CD2 1 
ATOM   13058 C CE1 . TYR C 1 497 ? 143.261 166.117 167.258 1.00 88.42  ? 497 TYR C CE1 1 
ATOM   13059 C CE2 . TYR C 1 497 ? 142.009 166.839 169.220 1.00 95.63  ? 497 TYR C CE2 1 
ATOM   13060 C CZ  . TYR C 1 497 ? 143.090 166.138 168.656 1.00 97.16  ? 497 TYR C CZ  1 
ATOM   13061 O OH  . TYR C 1 497 ? 143.966 165.504 169.474 1.00 97.91  ? 497 TYR C OH  1 
ATOM   13062 N N   . LEU C 1 498 ? 139.660 164.893 166.177 1.00 77.40  ? 498 LEU C N   1 
ATOM   13063 C CA  . LEU C 1 498 ? 140.320 163.596 166.008 1.00 79.30  ? 498 LEU C CA  1 
ATOM   13064 C C   . LEU C 1 498 ? 139.664 162.703 164.942 1.00 80.36  ? 498 LEU C C   1 
ATOM   13065 O O   . LEU C 1 498 ? 140.391 162.215 164.083 1.00 84.67  ? 498 LEU C O   1 
ATOM   13066 C CB  . LEU C 1 498 ? 140.494 162.888 167.359 1.00 76.11  ? 498 LEU C CB  1 
ATOM   13067 C CG  . LEU C 1 498 ? 141.308 161.589 167.252 1.00 76.53  ? 498 LEU C CG  1 
ATOM   13068 C CD1 . LEU C 1 498 ? 142.756 161.838 166.838 1.00 74.23  ? 498 LEU C CD1 1 
ATOM   13069 C CD2 . LEU C 1 498 ? 141.320 160.870 168.591 1.00 80.25  ? 498 LEU C CD2 1 
ATOM   13070 N N   . PRO C 1 499 ? 138.334 162.510 164.894 1.00 77.12  ? 499 PRO C N   1 
ATOM   13071 C CA  . PRO C 1 499 ? 137.716 161.759 163.803 1.00 77.13  ? 499 PRO C CA  1 
ATOM   13072 C C   . PRO C 1 499 ? 137.881 162.406 162.414 1.00 79.13  ? 499 PRO C C   1 
ATOM   13073 O O   . PRO C 1 499 ? 137.899 161.689 161.420 1.00 73.14  ? 499 PRO C O   1 
ATOM   13074 C CB  . PRO C 1 499 ? 136.256 161.562 164.217 1.00 73.78  ? 499 PRO C CB  1 
ATOM   13075 C CG  . PRO C 1 499 ? 135.998 162.654 165.242 1.00 76.72  ? 499 PRO C CG  1 
ATOM   13076 C CD  . PRO C 1 499 ? 137.350 162.806 165.921 1.00 77.67  ? 499 PRO C CD  1 
ATOM   13077 N N   . LEU C 1 500 ? 138.084 163.726 162.302 1.00 80.90  ? 500 LEU C N   1 
ATOM   13078 C CA  . LEU C 1 500 ? 138.468 164.362 161.032 1.00 75.15  ? 500 LEU C CA  1 
ATOM   13079 C C   . LEU C 1 500 ? 139.939 164.121 160.680 1.00 73.29  ? 500 LEU C C   1 
ATOM   13080 O O   . LEU C 1 500 ? 140.260 163.873 159.517 1.00 84.41  ? 500 LEU C O   1 
ATOM   13081 C CB  . LEU C 1 500 ? 138.209 165.876 161.066 1.00 76.01  ? 500 LEU C CB  1 
ATOM   13082 C CG  . LEU C 1 500 ? 136.756 166.347 161.173 1.00 75.82  ? 500 LEU C CG  1 
ATOM   13083 C CD1 . LEU C 1 500 ? 136.737 167.855 160.942 1.00 81.98  ? 500 LEU C CD1 1 
ATOM   13084 C CD2 . LEU C 1 500 ? 135.842 165.727 160.124 1.00 69.27  ? 500 LEU C CD2 1 
ATOM   13085 N N   . LEU C 1 501 ? 140.845 164.172 161.659 1.00 63.90  ? 501 LEU C N   1 
ATOM   13086 C CA  . LEU C 1 501 ? 142.263 163.870 161.440 1.00 69.74  ? 501 LEU C CA  1 
ATOM   13087 C C   . LEU C 1 501 ? 142.433 162.418 160.988 1.00 71.58  ? 501 LEU C C   1 
ATOM   13088 O O   . LEU C 1 501 ? 143.145 162.125 160.040 1.00 81.07  ? 501 LEU C O   1 
ATOM   13089 C CB  . LEU C 1 501 ? 143.054 164.156 162.728 1.00 70.50  ? 501 LEU C CB  1 
ATOM   13090 C CG  . LEU C 1 501 ? 144.567 163.921 162.589 1.00 68.73  ? 501 LEU C CG  1 
ATOM   13091 C CD1 . LEU C 1 501 ? 145.211 165.010 161.741 1.00 73.45  ? 501 LEU C CD1 1 
ATOM   13092 C CD2 . LEU C 1 501 ? 145.230 163.947 163.963 1.00 72.32  ? 501 LEU C CD2 1 
ATOM   13093 N N   . VAL C 1 502 ? 141.719 161.498 161.616 1.00 70.79  ? 502 VAL C N   1 
ATOM   13094 C CA  . VAL C 1 502 ? 141.742 160.077 161.275 1.00 70.10  ? 502 VAL C CA  1 
ATOM   13095 C C   . VAL C 1 502 ? 141.083 159.790 159.921 1.00 68.54  ? 502 VAL C C   1 
ATOM   13096 O O   . VAL C 1 502 ? 141.609 158.999 159.150 1.00 75.63  ? 502 VAL C O   1 
ATOM   13097 C CB  . VAL C 1 502 ? 141.124 159.295 162.438 1.00 74.86  ? 502 VAL C CB  1 
ATOM   13098 C CG1 . VAL C 1 502 ? 140.842 157.851 162.067 1.00 72.92  ? 502 VAL C CG1 1 
ATOM   13099 C CG2 . VAL C 1 502 ? 142.113 159.294 163.611 1.00 66.06  ? 502 VAL C CG2 1 
ATOM   13100 N N   . LEU C 1 503 ? 139.994 160.463 159.546 1.00 73.77  ? 503 LEU C N   1 
ATOM   13101 C CA  . LEU C 1 503 ? 139.432 160.335 158.199 1.00 76.85  ? 503 LEU C CA  1 
ATOM   13102 C C   . LEU C 1 503 ? 140.406 160.836 157.121 1.00 72.81  ? 503 LEU C C   1 
ATOM   13103 O O   . LEU C 1 503 ? 140.607 160.175 156.105 1.00 73.91  ? 503 LEU C O   1 
ATOM   13104 C CB  . LEU C 1 503 ? 138.083 161.072 158.144 1.00 72.50  ? 503 LEU C CB  1 
ATOM   13105 C CG  . LEU C 1 503 ? 137.414 161.046 156.760 1.00 77.59  ? 503 LEU C CG  1 
ATOM   13106 C CD1 . LEU C 1 503 ? 137.105 159.630 156.277 1.00 77.23  ? 503 LEU C CD1 1 
ATOM   13107 C CD2 . LEU C 1 503 ? 136.109 161.830 156.813 1.00 76.72  ? 503 LEU C CD2 1 
ATOM   13108 N N   . SER C 1 504 ? 141.044 161.985 157.339 1.00 68.80  ? 504 SER C N   1 
ATOM   13109 C CA  . SER C 1 504 ? 142.044 162.526 156.415 1.00 63.24  ? 504 SER C CA  1 
ATOM   13110 C C   . SER C 1 504 ? 143.355 161.736 156.406 1.00 65.76  ? 504 SER C C   1 
ATOM   13111 O O   . SER C 1 504 ? 144.038 161.733 155.388 1.00 79.83  ? 504 SER C O   1 
ATOM   13112 C CB  . SER C 1 504 ? 142.275 164.010 156.669 1.00 66.12  ? 504 SER C CB  1 
ATOM   13113 O OG  . SER C 1 504 ? 142.538 164.291 158.013 1.00 73.89  ? 504 SER C OG  1 
ATOM   13114 N N   . LEU C 1 505 ? 143.676 160.972 157.449 1.00 60.10  ? 505 LEU C N   1 
ATOM   13115 C CA  . LEU C 1 505 ? 144.742 159.969 157.432 1.00 58.43  ? 505 LEU C CA  1 
ATOM   13116 C C   . LEU C 1 505 ? 144.392 158.768 156.545 1.00 58.36  ? 505 LEU C C   1 
ATOM   13117 O O   . LEU C 1 505 ? 145.225 158.349 155.752 1.00 65.37  ? 505 LEU C O   1 
ATOM   13118 C CB  . LEU C 1 505 ? 145.019 159.550 158.882 1.00 66.73  ? 505 LEU C CB  1 
ATOM   13119 C CG  . LEU C 1 505 ? 146.026 158.411 159.079 1.00 61.78  ? 505 LEU C CG  1 
ATOM   13120 C CD1 . LEU C 1 505 ? 147.455 158.863 158.832 1.00 64.97  ? 505 LEU C CD1 1 
ATOM   13121 C CD2 . LEU C 1 505 ? 145.909 157.928 160.518 1.00 61.00  ? 505 LEU C CD2 1 
ATOM   13122 N N   . VAL C 1 506 ? 143.165 158.240 156.620 1.00 65.39  ? 506 VAL C N   1 
ATOM   13123 C CA  . VAL C 1 506 ? 142.704 157.154 155.738 1.00 58.30  ? 506 VAL C CA  1 
ATOM   13124 C C   . VAL C 1 506 ? 142.714 157.611 154.290 1.00 66.68  ? 506 VAL C C   1 
ATOM   13125 O O   . VAL C 1 506 ? 143.409 157.017 153.477 1.00 71.39  ? 506 VAL C O   1 
ATOM   13126 C CB  . VAL C 1 506 ? 141.303 156.638 156.096 1.00 55.72  ? 506 VAL C CB  1 
ATOM   13127 C CG1 . VAL C 1 506 ? 140.799 155.617 155.083 1.00 62.78  ? 506 VAL C CG1 1 
ATOM   13128 C CG2 . VAL C 1 506 ? 141.298 155.953 157.448 1.00 56.67  ? 506 VAL C CG2 1 
ATOM   13129 N N   . LEU C 1 507 ? 142.011 158.701 153.963 1.00 66.50  ? 507 LEU C N   1 
ATOM   13130 C CA  . LEU C 1 507 ? 142.044 159.282 152.620 1.00 53.00  ? 507 LEU C CA  1 
ATOM   13131 C C   . LEU C 1 507 ? 143.474 159.557 152.171 1.00 53.75  ? 507 LEU C C   1 
ATOM   13132 O O   . LEU C 1 507 ? 143.809 159.299 151.028 1.00 72.93  ? 507 LEU C O   1 
ATOM   13133 C CB  . LEU C 1 507 ? 141.246 160.589 152.599 1.00 61.02  ? 507 LEU C CB  1 
ATOM   13134 C CG  . LEU C 1 507 ? 139.771 160.374 152.262 1.00 64.60  ? 507 LEU C CG  1 
ATOM   13135 C CD1 . LEU C 1 507 ? 138.983 161.616 152.646 1.00 63.46  ? 507 LEU C CD1 1 
ATOM   13136 C CD2 . LEU C 1 507 ? 139.587 160.134 150.767 1.00 60.24  ? 507 LEU C CD2 1 
ATOM   13137 N N   . GLY C 1 508 ? 144.335 160.025 153.064 1.00 43.90  ? 508 GLY C N   1 
ATOM   13138 C CA  . GLY C 1 508 ? 145.730 160.272 152.770 1.00 50.38  ? 508 GLY C CA  1 
ATOM   13139 C C   . GLY C 1 508 ? 146.462 159.058 152.216 1.00 48.00  ? 508 GLY C C   1 
ATOM   13140 O O   . GLY C 1 508 ? 147.148 159.187 151.210 1.00 62.85  ? 508 GLY C O   1 
ATOM   13141 N N   . TRP C 1 509 ? 146.291 157.881 152.813 1.00 57.66  ? 509 TRP C N   1 
ATOM   13142 C CA  . TRP C 1 509 ? 146.891 156.642 152.315 1.00 50.25  ? 509 TRP C CA  1 
ATOM   13143 C C   . TRP C 1 509 ? 146.152 156.074 151.108 1.00 52.50  ? 509 TRP C C   1 
ATOM   13144 O O   . TRP C 1 509 ? 146.797 155.602 150.187 1.00 56.92  ? 509 TRP C O   1 
ATOM   13145 C CB  . TRP C 1 509 ? 146.991 155.611 153.441 1.00 60.27  ? 509 TRP C CB  1 
ATOM   13146 C CG  . TRP C 1 509 ? 148.092 155.887 154.416 1.00 58.87  ? 509 TRP C CG  1 
ATOM   13147 C CD1 . TRP C 1 509 ? 147.952 156.450 155.632 1.00 51.25  ? 509 TRP C CD1 1 
ATOM   13148 C CD2 . TRP C 1 509 ? 149.526 155.675 154.244 1.00 66.24  ? 509 TRP C CD2 1 
ATOM   13149 N NE1 . TRP C 1 509 ? 149.194 156.651 156.192 1.00 55.67  ? 509 TRP C NE1 1 
ATOM   13150 C CE2 . TRP C 1 509 ? 150.201 156.226 155.368 1.00 65.99  ? 509 TRP C CE2 1 
ATOM   13151 C CE3 . TRP C 1 509 ? 150.335 155.090 153.250 1.00 65.03  ? 509 TRP C CE3 1 
ATOM   13152 C CZ2 . TRP C 1 509 ? 151.598 156.258 155.475 1.00 62.51  ? 509 TRP C CZ2 1 
ATOM   13153 C CZ3 . TRP C 1 509 ? 151.743 155.111 153.350 1.00 69.21  ? 509 TRP C CZ3 1 
ATOM   13154 C CH2 . TRP C 1 509 ? 152.378 155.708 154.450 1.00 64.60  ? 509 TRP C CH2 1 
ATOM   13155 N N   . LEU C 1 510 ? 144.825 156.167 151.031 1.00 65.02  ? 510 LEU C N   1 
ATOM   13156 C CA  . LEU C 1 510 ? 144.083 155.768 149.828 1.00 60.58  ? 510 LEU C CA  1 
ATOM   13157 C C   . LEU C 1 510 ? 144.511 156.585 148.605 1.00 62.65  ? 510 LEU C C   1 
ATOM   13158 O O   . LEU C 1 510 ? 144.735 156.034 147.535 1.00 71.09  ? 510 LEU C O   1 
ATOM   13159 C CB  . LEU C 1 510 ? 142.569 155.897 150.060 1.00 57.51  ? 510 LEU C CB  1 
ATOM   13160 C CG  . LEU C 1 510 ? 141.990 155.002 151.163 1.00 61.49  ? 510 LEU C CG  1 
ATOM   13161 C CD1 . LEU C 1 510 ? 140.486 155.215 151.248 1.00 56.78  ? 510 LEU C CD1 1 
ATOM   13162 C CD2 . LEU C 1 510 ? 142.257 153.535 150.912 1.00 57.27  ? 510 LEU C CD2 1 
ATOM   13163 N N   . ASN C 1 511 ? 144.724 157.887 148.767 1.00 58.81  ? 511 ASN C N   1 
ATOM   13164 C CA  . ASN C 1 511 ? 145.260 158.777 147.746 1.00 50.23  ? 511 ASN C CA  1 
ATOM   13165 C C   . ASN C 1 511 ? 146.664 158.391 147.289 1.00 49.70  ? 511 ASN C C   1 
ATOM   13166 O O   . ASN C 1 511 ? 147.046 158.736 146.184 1.00 61.09  ? 511 ASN C O   1 
ATOM   13167 C CB  . ASN C 1 511 ? 145.276 160.203 148.296 1.00 47.42  ? 511 ASN C CB  1 
ATOM   13168 C CG  . ASN C 1 511 ? 143.921 160.852 148.369 1.00 55.68  ? 511 ASN C CG  1 
ATOM   13169 O OD1 . ASN C 1 511 ? 142.926 160.325 147.912 1.00 61.27  ? 511 ASN C OD1 1 
ATOM   13170 N ND2 . ASN C 1 511 ? 143.843 162.038 148.916 1.00 54.25  ? 511 ASN C ND2 1 
ATOM   13171 N N   . LEU C 1 512 ? 147.430 157.638 148.074 1.00 57.24  ? 512 LEU C N   1 
ATOM   13172 C CA  . LEU C 1 512 ? 148.745 157.139 147.677 1.00 54.61  ? 512 LEU C CA  1 
ATOM   13173 C C   . LEU C 1 512 ? 148.643 156.162 146.501 1.00 49.26  ? 512 LEU C C   1 
ATOM   13174 O O   . LEU C 1 512 ? 149.584 156.013 145.732 1.00 51.47  ? 512 LEU C O   1 
ATOM   13175 C CB  . LEU C 1 512 ? 149.397 156.469 148.894 1.00 54.57  ? 512 LEU C CB  1 
ATOM   13176 C CG  . LEU C 1 512 ? 150.916 156.341 148.811 1.00 55.95  ? 512 LEU C CG  1 
ATOM   13177 C CD1 . LEU C 1 512 ? 151.583 157.706 148.912 1.00 59.62  ? 512 LEU C CD1 1 
ATOM   13178 C CD2 . LEU C 1 512 ? 151.413 155.515 149.978 1.00 57.00  ? 512 LEU C CD2 1 
ATOM   13179 N N   . LEU C 1 513 ? 147.479 155.550 146.285 1.00 49.64  ? 513 LEU C N   1 
ATOM   13180 C CA  . LEU C 1 513 ? 147.224 154.710 145.120 1.00 53.10  ? 513 LEU C CA  1 
ATOM   13181 C C   . LEU C 1 513 ? 147.146 155.501 143.820 1.00 51.95  ? 513 LEU C C   1 
ATOM   13182 O O   . LEU C 1 513 ? 147.261 154.889 142.759 1.00 57.43  ? 513 LEU C O   1 
ATOM   13183 C CB  . LEU C 1 513 ? 145.943 153.891 145.317 1.00 55.32  ? 513 LEU C CB  1 
ATOM   13184 C CG  . LEU C 1 513 ? 146.029 152.915 146.487 1.00 49.68  ? 513 LEU C CG  1 
ATOM   13185 C CD1 . LEU C 1 513 ? 144.641 152.413 146.834 1.00 49.03  ? 513 LEU C CD1 1 
ATOM   13186 C CD2 . LEU C 1 513 ? 146.931 151.732 146.162 1.00 42.30  ? 513 LEU C CD2 1 
ATOM   13187 N N   . TYR C 1 514 ? 147.046 156.834 143.824 1.00 56.24  ? 514 TYR C N   1 
ATOM   13188 C CA  . TYR C 1 514 ? 147.150 157.623 142.594 1.00 41.60  ? 514 TYR C CA  1 
ATOM   13189 C C   . TYR C 1 514 ? 148.438 157.293 141.841 1.00 50.20  ? 514 TYR C C   1 
ATOM   13190 O O   . TYR C 1 514 ? 148.410 156.992 140.650 1.00 67.15  ? 514 TYR C O   1 
ATOM   13191 C CB  . TYR C 1 514 ? 147.078 159.117 142.919 1.00 43.06  ? 514 TYR C CB  1 
ATOM   13192 C CG  . TYR C 1 514 ? 147.446 160.019 141.759 1.00 37.37  ? 514 TYR C CG  1 
ATOM   13193 C CD1 . TYR C 1 514 ? 146.519 160.296 140.746 1.00 51.27  ? 514 TYR C CD1 1 
ATOM   13194 C CD2 . TYR C 1 514 ? 148.739 160.553 141.675 1.00 59.11  ? 514 TYR C CD2 1 
ATOM   13195 C CE1 . TYR C 1 514 ? 146.894 161.086 139.646 1.00 65.13  ? 514 TYR C CE1 1 
ATOM   13196 C CE2 . TYR C 1 514 ? 149.131 161.326 140.572 1.00 56.16  ? 514 TYR C CE2 1 
ATOM   13197 C CZ  . TYR C 1 514 ? 148.206 161.591 139.546 1.00 66.79  ? 514 TYR C CZ  1 
ATOM   13198 O OH  . TYR C 1 514 ? 148.572 162.329 138.469 1.00 67.85  ? 514 TYR C OH  1 
ATOM   13199 N N   . TYR C 1 515 ? 149.564 157.262 142.551 1.00 56.41  ? 515 TYR C N   1 
ATOM   13200 C CA  . TYR C 1 515 ? 150.896 157.142 141.965 1.00 46.15  ? 515 TYR C CA  1 
ATOM   13201 C C   . TYR C 1 515 ? 151.219 155.752 141.420 1.00 43.90  ? 515 TYR C C   1 
ATOM   13202 O O   . TYR C 1 515 ? 152.246 155.573 140.777 1.00 55.09  ? 515 TYR C O   1 
ATOM   13203 C CB  . TYR C 1 515 ? 151.931 157.611 142.984 1.00 42.25  ? 515 TYR C CB  1 
ATOM   13204 C CG  . TYR C 1 515 ? 151.711 159.036 143.445 1.00 46.11  ? 515 TYR C CG  1 
ATOM   13205 C CD1 . TYR C 1 515 ? 152.174 160.104 142.659 1.00 55.54  ? 515 TYR C CD1 1 
ATOM   13206 C CD2 . TYR C 1 515 ? 151.035 159.295 144.650 1.00 48.88  ? 515 TYR C CD2 1 
ATOM   13207 C CE1 . TYR C 1 515 ? 151.974 161.428 143.078 1.00 54.03  ? 515 TYR C CE1 1 
ATOM   13208 C CE2 . TYR C 1 515 ? 150.845 160.615 145.077 1.00 46.58  ? 515 TYR C CE2 1 
ATOM   13209 C CZ  . TYR C 1 515 ? 151.313 161.685 144.293 1.00 55.69  ? 515 TYR C CZ  1 
ATOM   13210 O OH  . TYR C 1 515 ? 151.125 162.954 144.717 1.00 65.29  ? 515 TYR C OH  1 
ATOM   13211 N N   . THR C 1 516 ? 150.334 154.766 141.574 1.00 53.88  ? 516 THR C N   1 
ATOM   13212 C CA  . THR C 1 516 ? 150.504 153.443 140.947 1.00 44.85  ? 516 THR C CA  1 
ATOM   13213 C C   . THR C 1 516 ? 150.571 153.514 139.421 1.00 57.44  ? 516 THR C C   1 
ATOM   13214 O O   . THR C 1 516 ? 151.156 152.623 138.815 1.00 65.38  ? 516 THR C O   1 
ATOM   13215 C CB  . THR C 1 516 ? 149.407 152.454 141.347 1.00 57.15  ? 516 THR C CB  1 
ATOM   13216 O OG1 . THR C 1 516 ? 148.127 152.930 141.017 1.00 68.73  ? 516 THR C OG1 1 
ATOM   13217 C CG2 . THR C 1 516 ? 149.438 152.098 142.820 1.00 52.56  ? 516 THR C CG2 1 
ATOM   13218 N N   . ARG C 1 517 ? 150.053 154.578 138.792 1.00 64.92  ? 517 ARG C N   1 
ATOM   13219 C CA  . ARG C 1 517 ? 150.132 154.847 137.343 1.00 59.58  ? 517 ARG C CA  1 
ATOM   13220 C C   . ARG C 1 517 ? 151.524 155.180 136.817 1.00 62.85  ? 517 ARG C C   1 
ATOM   13221 O O   . ARG C 1 517 ? 151.699 155.234 135.606 1.00 69.45  ? 517 ARG C O   1 
ATOM   13222 C CB  . ARG C 1 517 ? 149.122 155.935 136.947 1.00 54.02  ? 517 ARG C CB  1 
ATOM   13223 C CG  . ARG C 1 517 ? 149.503 157.345 137.427 1.00 48.83  ? 517 ARG C CG  1 
ATOM   13224 C CD  . ARG C 1 517 ? 148.358 158.342 137.275 1.00 49.93  ? 517 ARG C CD  1 
ATOM   13225 N NE  . ARG C 1 517 ? 147.207 157.937 138.097 1.00 57.68  ? 517 ARG C NE  1 
ATOM   13226 C CZ  . ARG C 1 517 ? 145.941 158.215 137.882 1.00 60.14  ? 517 ARG C CZ  1 
ATOM   13227 N NH1 . ARG C 1 517 ? 145.020 157.610 138.560 1.00 53.59  ? 517 ARG C NH1 1 
ATOM   13228 N NH2 . ARG C 1 517 ? 145.565 159.079 136.990 1.00 62.20  ? 517 ARG C NH2 1 
ATOM   13229 N N   . GLY C 1 518 ? 152.513 155.402 137.676 1.00 67.57  ? 518 GLY C N   1 
ATOM   13230 C CA  . GLY C 1 518 ? 153.866 155.739 137.240 1.00 64.26  ? 518 GLY C CA  1 
ATOM   13231 C C   . GLY C 1 518 ? 154.622 154.583 136.593 1.00 69.59  ? 518 GLY C C   1 
ATOM   13232 O O   . GLY C 1 518 ? 155.520 154.818 135.793 1.00 75.00  ? 518 GLY C O   1 
ATOM   13233 N N   . PHE C 1 519 ? 154.250 153.338 136.888 1.00 64.80  ? 519 PHE C N   1 
ATOM   13234 C CA  . PHE C 1 519 ? 154.838 152.134 136.303 1.00 70.20  ? 519 PHE C CA  1 
ATOM   13235 C C   . PHE C 1 519 ? 153.795 151.360 135.517 1.00 73.44  ? 519 PHE C C   1 
ATOM   13236 O O   . PHE C 1 519 ? 152.643 151.287 135.931 1.00 73.56  ? 519 PHE C O   1 
ATOM   13237 C CB  . PHE C 1 519 ? 155.433 151.236 137.392 1.00 75.42  ? 519 PHE C CB  1 
ATOM   13238 C CG  . PHE C 1 519 ? 156.457 151.895 138.287 1.00 78.05  ? 519 PHE C CG  1 
ATOM   13239 C CD1 . PHE C 1 519 ? 157.751 152.146 137.800 1.00 73.08  ? 519 PHE C CD1 1 
ATOM   13240 C CD2 . PHE C 1 519 ? 156.124 152.251 139.604 1.00 73.34  ? 519 PHE C CD2 1 
ATOM   13241 C CE1 . PHE C 1 519 ? 158.708 152.755 138.624 1.00 69.27  ? 519 PHE C CE1 1 
ATOM   13242 C CE2 . PHE C 1 519 ? 157.084 152.857 140.430 1.00 75.92  ? 519 PHE C CE2 1 
ATOM   13243 C CZ  . PHE C 1 519 ? 158.374 153.109 139.940 1.00 70.39  ? 519 PHE C CZ  1 
ATOM   13244 N N   . GLN C 1 520 ? 154.195 150.728 134.417 1.00 83.46  ? 520 GLN C N   1 
ATOM   13245 C CA  . GLN C 1 520 ? 153.280 149.959 133.580 1.00 80.69  ? 520 GLN C CA  1 
ATOM   13246 C C   . GLN C 1 520 ? 152.573 148.845 134.350 1.00 77.12  ? 520 GLN C C   1 
ATOM   13247 O O   . GLN C 1 520 ? 151.364 148.707 134.244 1.00 74.90  ? 520 GLN C O   1 
ATOM   13248 C CB  . GLN C 1 520 ? 154.039 149.408 132.366 1.00 80.75  ? 520 GLN C CB  1 
ATOM   13249 C CG  . GLN C 1 520 ? 153.082 148.694 131.400 1.00 81.23  ? 520 GLN C CG  1 
ATOM   13250 C CD  . GLN C 1 520 ? 153.644 148.457 130.003 1.00 85.42  ? 520 GLN C CD  1 
ATOM   13251 O OE1 . GLN C 1 520 ? 154.618 149.049 129.565 1.00 86.40  ? 520 GLN C OE1 1 
ATOM   13252 N NE2 . GLN C 1 520 ? 153.040 147.579 129.236 1.00 83.35  ? 520 GLN C NE2 1 
ATOM   13253 N N   . HIS C 1 521 ? 153.288 148.060 135.154 1.00 85.96  ? 521 HIS C N   1 
ATOM   13254 C CA  . HIS C 1 521 ? 152.704 146.877 135.785 1.00 88.21  ? 521 HIS C CA  1 
ATOM   13255 C C   . HIS C 1 521 ? 151.666 147.217 136.841 1.00 90.82  ? 521 HIS C C   1 
ATOM   13256 O O   . HIS C 1 521 ? 150.538 146.747 136.732 1.00 91.83  ? 521 HIS C O   1 
ATOM   13257 C CB  . HIS C 1 521 ? 153.807 145.932 136.268 1.00 86.83  ? 521 HIS C CB  1 
ATOM   13258 C CG  . HIS C 1 521 ? 154.456 145.283 135.074 1.00 94.75  ? 521 HIS C CG  1 
ATOM   13259 N ND1 . HIS C 1 521 ? 153.865 144.287 134.296 1.00 89.69  ? 521 HIS C ND1 1 
ATOM   13260 C CD2 . HIS C 1 521 ? 155.607 145.692 134.470 1.00 94.10  ? 521 HIS C CD2 1 
ATOM   13261 C CE1 . HIS C 1 521 ? 154.681 144.110 133.246 1.00 90.45  ? 521 HIS C CE1 1 
ATOM   13262 N NE2 . HIS C 1 521 ? 155.735 144.935 133.328 1.00 91.76  ? 521 HIS C NE2 1 
ATOM   13263 N N   . THR C 1 522 ? 151.969 148.072 137.814 1.00 82.26  ? 522 THR C N   1 
ATOM   13264 C CA  . THR C 1 522 ? 150.966 148.556 138.777 1.00 73.99  ? 522 THR C CA  1 
ATOM   13265 C C   . THR C 1 522 ? 149.913 149.461 138.127 1.00 82.26  ? 522 THR C C   1 
ATOM   13266 O O   . THR C 1 522 ? 148.746 149.392 138.504 1.00 71.79  ? 522 THR C O   1 
ATOM   13267 C CB  . THR C 1 522 ? 151.634 149.290 139.946 1.00 65.54  ? 522 THR C CB  1 
ATOM   13268 O OG1 . THR C 1 522 ? 152.491 150.311 139.500 1.00 76.86  ? 522 THR C OG1 1 
ATOM   13269 C CG2 . THR C 1 522 ? 152.476 148.344 140.789 1.00 64.34  ? 522 THR C CG2 1 
ATOM   13270 N N   . GLY C 1 523 ? 150.291 150.267 137.130 1.00 83.56  ? 523 GLY C N   1 
ATOM   13271 C CA  . GLY C 1 523 ? 149.439 151.276 136.496 1.00 68.09  ? 523 GLY C CA  1 
ATOM   13272 C C   . GLY C 1 523 ? 148.400 150.715 135.540 1.00 73.13  ? 523 GLY C C   1 
ATOM   13273 O O   . GLY C 1 523 ? 147.288 151.221 135.484 1.00 76.54  ? 523 GLY C O   1 
ATOM   13274 N N   . ILE C 1 524 ? 148.717 149.625 134.847 1.00 79.24  ? 524 ILE C N   1 
ATOM   13275 C CA  . ILE C 1 524 ? 147.741 148.832 134.100 1.00 80.83  ? 524 ILE C CA  1 
ATOM   13276 C C   . ILE C 1 524 ? 146.837 148.032 135.044 1.00 85.77  ? 524 ILE C C   1 
ATOM   13277 O O   . ILE C 1 524 ? 145.644 147.932 134.785 1.00 82.02  ? 524 ILE C O   1 
ATOM   13278 C CB  . ILE C 1 524 ? 148.473 147.939 133.078 1.00 83.52  ? 524 ILE C CB  1 
ATOM   13279 C CG1 . ILE C 1 524 ? 148.941 148.847 131.925 1.00 77.39  ? 524 ILE C CG1 1 
ATOM   13280 C CG2 . ILE C 1 524 ? 147.597 146.796 132.571 1.00 84.18  ? 524 ILE C CG2 1 
ATOM   13281 C CD1 . ILE C 1 524 ? 149.689 148.120 130.814 1.00 78.40  ? 524 ILE C CD1 1 
ATOM   13282 N N   . TYR C 1 525 ? 147.336 147.503 136.164 1.00 83.84  ? 525 TYR C N   1 
ATOM   13283 C CA  . TYR C 1 525 ? 146.474 146.760 137.078 1.00 83.40  ? 525 TYR C CA  1 
ATOM   13284 C C   . TYR C 1 525 ? 145.447 147.652 137.778 1.00 82.40  ? 525 TYR C C   1 
ATOM   13285 O O   . TYR C 1 525 ? 144.273 147.301 137.836 1.00 81.65  ? 525 TYR C O   1 
ATOM   13286 C CB  . TYR C 1 525 ? 147.298 145.972 138.085 1.00 83.87  ? 525 TYR C CB  1 
ATOM   13287 C CG  . TYR C 1 525 ? 146.467 144.921 138.783 1.00 81.03  ? 525 TYR C CG  1 
ATOM   13288 C CD1 . TYR C 1 525 ? 146.008 143.814 138.050 1.00 79.24  ? 525 TYR C CD1 1 
ATOM   13289 C CD2 . TYR C 1 525 ? 146.093 145.084 140.129 1.00 80.51  ? 525 TYR C CD2 1 
ATOM   13290 C CE1 . TYR C 1 525 ? 145.170 142.865 138.658 1.00 83.94  ? 525 TYR C CE1 1 
ATOM   13291 C CE2 . TYR C 1 525 ? 145.268 144.125 140.744 1.00 83.04  ? 525 TYR C CE2 1 
ATOM   13292 C CZ  . TYR C 1 525 ? 144.804 143.015 140.007 1.00 82.24  ? 525 TYR C CZ  1 
ATOM   13293 O OH  . TYR C 1 525 ? 143.995 142.097 140.584 1.00 74.13  ? 525 TYR C OH  1 
ATOM   13294 N N   . SER C 1 526 ? 145.836 148.857 138.198 1.00 81.33  ? 526 SER C N   1 
ATOM   13295 C CA  . SER C 1 526 ? 144.893 149.872 138.682 1.00 82.45  ? 526 SER C CA  1 
ATOM   13296 C C   . SER C 1 526 ? 143.778 150.208 137.684 1.00 81.27  ? 526 SER C C   1 
ATOM   13297 O O   . SER C 1 526 ? 142.724 150.689 138.080 1.00 83.05  ? 526 SER C O   1 
ATOM   13298 C CB  . SER C 1 526 ? 145.649 151.146 139.062 1.00 85.48  ? 526 SER C CB  1 
ATOM   13299 O OG  . SER C 1 526 ? 146.475 150.884 140.177 1.00 82.43  ? 526 SER C OG  1 
ATOM   13300 N N   . VAL C 1 527 ? 143.975 149.917 136.397 1.00 88.33  ? 527 VAL C N   1 
ATOM   13301 C CA  . VAL C 1 527 ? 142.988 150.053 135.320 1.00 87.86  ? 527 VAL C CA  1 
ATOM   13302 C C   . VAL C 1 527 ? 142.218 148.753 135.044 1.00 90.09  ? 527 VAL C C   1 
ATOM   13303 O O   . VAL C 1 527 ? 141.040 148.806 134.705 1.00 89.88  ? 527 VAL C O   1 
ATOM   13304 C CB  . VAL C 1 527 ? 143.717 150.561 134.075 1.00 85.09  ? 527 VAL C CB  1 
ATOM   13305 C CG1 . VAL C 1 527 ? 142.860 150.525 132.827 1.00 86.41  ? 527 VAL C CG1 1 
ATOM   13306 C CG2 . VAL C 1 527 ? 144.164 152.008 134.260 1.00 85.01  ? 527 VAL C CG2 1 
ATOM   13307 N N   . MET C 1 528 ? 142.833 147.579 135.208 1.00 97.92  ? 528 MET C N   1 
ATOM   13308 C CA  . MET C 1 528 ? 142.139 146.285 135.115 1.00 97.18  ? 528 MET C CA  1 
ATOM   13309 C C   . MET C 1 528 ? 141.064 146.120 136.190 1.00 94.61  ? 528 MET C C   1 
ATOM   13310 O O   . MET C 1 528 ? 139.977 145.634 135.888 1.00 92.84  ? 528 MET C O   1 
ATOM   13311 C CB  . MET C 1 528 ? 143.126 145.124 135.265 1.00 96.35  ? 528 MET C CB  1 
ATOM   13312 C CG  . MET C 1 528 ? 144.047 144.937 134.061 1.00 99.60  ? 528 MET C CG  1 
ATOM   13313 S SD  . MET C 1 528 ? 145.351 143.700 134.306 1.00 108.41 ? 528 MET C SD  1 
ATOM   13314 C CE  . MET C 1 528 ? 144.360 142.225 134.640 1.00 94.89  ? 528 MET C CE  1 
ATOM   13315 N N   . ILE C 1 529 ? 141.405 146.512 137.416 1.00 95.56  ? 529 ILE C N   1 
ATOM   13316 C CA  . ILE C 1 529 ? 140.605 146.272 138.605 1.00 92.51  ? 529 ILE C CA  1 
ATOM   13317 C C   . ILE C 1 529 ? 139.378 147.199 138.675 1.00 92.75  ? 529 ILE C C   1 
ATOM   13318 O O   . ILE C 1 529 ? 138.261 146.701 138.773 1.00 91.37  ? 529 ILE C O   1 
ATOM   13319 C CB  . ILE C 1 529 ? 141.554 146.266 139.831 1.00 91.99  ? 529 ILE C CB  1 
ATOM   13320 C CG1 . ILE C 1 529 ? 140.944 145.510 141.022 1.00 90.78  ? 529 ILE C CG1 1 
ATOM   13321 C CG2 . ILE C 1 529 ? 142.021 147.661 140.270 1.00 90.26  ? 529 ILE C CG2 1 
ATOM   13322 C CD1 . ILE C 1 529 ? 141.985 144.936 141.977 1.00 89.15  ? 529 ILE C CD1 1 
ATOM   13323 N N   . GLN C 1 530 ? 139.530 148.525 138.587 1.00 97.92  ? 530 GLN C N   1 
ATOM   13324 C CA  . GLN C 1 530 ? 138.398 149.460 138.695 1.00 96.49  ? 530 GLN C CA  1 
ATOM   13325 C C   . GLN C 1 530 ? 137.550 149.465 137.415 1.00 94.61  ? 530 GLN C C   1 
ATOM   13326 O O   . GLN C 1 530 ? 138.085 149.680 136.331 1.00 94.03  ? 530 GLN C O   1 
ATOM   13327 C CB  . GLN C 1 530 ? 138.893 150.858 139.114 1.00 93.24  ? 530 GLN C CB  1 
ATOM   13328 C CG  . GLN C 1 530 ? 139.606 151.664 138.017 1.00 94.46  ? 530 GLN C CG  1 
ATOM   13329 C CD  . GLN C 1 530 ? 140.409 152.863 138.530 1.00 98.38  ? 530 GLN C CD  1 
ATOM   13330 O OE1 . GLN C 1 530 ? 140.596 153.092 139.720 1.00 99.03  ? 530 GLN C OE1 1 
ATOM   13331 N NE2 . GLN C 1 530 ? 140.874 153.718 137.652 1.00 97.52  ? 530 GLN C NE2 1 
ATOM   13332 N N   . LYS C 1 531 ? 136.236 149.204 137.515 1.00 91.25  ? 531 LYS C N   1 
ATOM   13333 C CA  . LYS C 1 531 ? 135.349 149.029 136.344 1.00 95.79  ? 531 LYS C CA  1 
ATOM   13334 C C   . LYS C 1 531 ? 133.850 149.216 136.640 1.00 99.98  ? 531 LYS C C   1 
ATOM   13335 O O   . LYS C 1 531 ? 133.474 149.713 137.701 1.00 92.48  ? 531 LYS C O   1 
ATOM   13336 C CB  . LYS C 1 531 ? 135.684 147.677 135.665 1.00 90.62  ? 531 LYS C CB  1 
ATOM   13337 C CG  . LYS C 1 531 ? 135.337 146.400 136.451 1.00 84.08  ? 531 LYS C CG  1 
ATOM   13338 C CD  . LYS C 1 531 ? 136.186 145.200 135.993 1.00 88.92  ? 531 LYS C CD  1 
ATOM   13339 C CE  . LYS C 1 531 ? 136.093 144.952 134.477 1.00 90.70  ? 531 LYS C CE  1 
ATOM   13340 N NZ  . LYS C 1 531 ? 137.102 143.975 133.997 1.00 83.80  ? 531 LYS C NZ  1 
ATOM   13341 N N   . VAL C 1 532 ? 133.006 148.762 135.702 1.00 108.16 ? 532 VAL C N   1 
ATOM   13342 C CA  . VAL C 1 532 ? 131.516 148.726 135.685 1.00 99.51  ? 532 VAL C CA  1 
ATOM   13343 C C   . VAL C 1 532 ? 130.870 148.192 136.975 1.00 95.06  ? 532 VAL C C   1 
ATOM   13344 O O   . VAL C 1 532 ? 129.723 148.508 137.278 1.00 96.47  ? 532 VAL C O   1 
ATOM   13345 C CB  . VAL C 1 532 ? 131.070 147.879 134.468 1.00 97.06  ? 532 VAL C CB  1 
ATOM   13346 C CG1 . VAL C 1 532 ? 129.597 147.479 134.461 1.00 93.95  ? 532 VAL C CG1 1 
ATOM   13347 C CG2 . VAL C 1 532 ? 131.341 148.637 133.161 1.00 96.78  ? 532 VAL C CG2 1 
ATOM   13348 N N   . ILE C 1 533 ? 131.615 147.460 137.795 1.00 90.50  ? 533 ILE C N   1 
ATOM   13349 C CA  . ILE C 1 533 ? 131.205 147.039 139.138 1.00 88.90  ? 533 ILE C CA  1 
ATOM   13350 C C   . ILE C 1 533 ? 130.768 148.235 140.005 1.00 90.60  ? 533 ILE C C   1 
ATOM   13351 O O   . ILE C 1 533 ? 129.788 148.122 140.734 1.00 93.35  ? 533 ILE C O   1 
ATOM   13352 C CB  . ILE C 1 533 ? 132.354 146.214 139.757 1.00 89.22  ? 533 ILE C CB  1 
ATOM   13353 C CG1 . ILE C 1 533 ? 132.520 144.902 138.958 1.00 92.45  ? 533 ILE C CG1 1 
ATOM   13354 C CG2 . ILE C 1 533 ? 132.114 145.903 141.240 1.00 90.34  ? 533 ILE C CG2 1 
ATOM   13355 C CD1 . ILE C 1 533 ? 133.845 144.188 139.199 1.00 92.90  ? 533 ILE C CD1 1 
ATOM   13356 N N   . LEU C 1 534 ? 131.394 149.414 139.880 1.00 92.52  ? 534 LEU C N   1 
ATOM   13357 C CA  . LEU C 1 534 ? 130.989 150.607 140.639 1.00 85.01  ? 534 LEU C CA  1 
ATOM   13358 C C   . LEU C 1 534 ? 129.596 151.136 140.260 1.00 84.45  ? 534 LEU C C   1 
ATOM   13359 O O   . LEU C 1 534 ? 128.902 151.698 141.106 1.00 84.27  ? 534 LEU C O   1 
ATOM   13360 C CB  . LEU C 1 534 ? 132.037 151.724 140.466 1.00 90.88  ? 534 LEU C CB  1 
ATOM   13361 C CG  . LEU C 1 534 ? 133.437 151.414 141.026 1.00 93.01  ? 534 LEU C CG  1 
ATOM   13362 C CD1 . LEU C 1 534 ? 134.375 152.575 140.715 1.00 86.83  ? 534 LEU C CD1 1 
ATOM   13363 C CD2 . LEU C 1 534 ? 133.435 151.201 142.536 1.00 88.11  ? 534 LEU C CD2 1 
ATOM   13364 N N   . ARG C 1 535 ? 129.168 150.855 139.013 1.00 95.69  ? 535 ARG C N   1 
ATOM   13365 C CA  . ARG C 1 535 ? 127.837 151.285 138.484 1.00 96.73  ? 535 ARG C CA  1 
ATOM   13366 C C   . ARG C 1 535 ? 126.732 150.368 138.996 1.00 94.38  ? 535 ARG C C   1 
ATOM   13367 O O   . ARG C 1 535 ? 125.679 150.887 139.414 1.00 91.59  ? 535 ARG C O   1 
ATOM   13368 C CB  . ARG C 1 535 ? 127.841 151.183 136.943 1.00 96.33  ? 535 ARG C CB  1 
ATOM   13369 C CG  . ARG C 1 535 ? 126.531 151.604 136.254 1.00 91.80  ? 535 ARG C CG  1 
ATOM   13370 C CD  . ARG C 1 535 ? 126.480 151.099 134.800 1.00 93.45  ? 535 ARG C CD  1 
ATOM   13371 N NE  . ARG C 1 535 ? 126.260 149.642 134.746 1.00 96.57  ? 535 ARG C NE  1 
ATOM   13372 C CZ  . ARG C 1 535 ? 126.218 148.920 133.633 1.00 96.76  ? 535 ARG C CZ  1 
ATOM   13373 N NH1 . ARG C 1 535 ? 126.013 147.616 133.700 1.00 92.71  ? 535 ARG C NH1 1 
ATOM   13374 N NH2 . ARG C 1 535 ? 126.385 149.502 132.458 1.00 93.94  ? 535 ARG C NH2 1 
ATOM   13375 N N   . ASP C 1 536 ? 126.968 149.060 138.964 1.00 92.54  ? 536 ASP C N   1 
ATOM   13376 C CA  . ASP C 1 536 ? 125.960 148.064 139.327 1.00 86.00  ? 536 ASP C CA  1 
ATOM   13377 C C   . ASP C 1 536 ? 125.869 147.770 140.818 1.00 86.46  ? 536 ASP C C   1 
ATOM   13378 O O   . ASP C 1 536 ? 124.773 147.528 141.312 1.00 93.57  ? 536 ASP C O   1 
ATOM   13379 C CB  . ASP C 1 536 ? 126.195 146.779 138.538 1.00 89.61  ? 536 ASP C CB  1 
ATOM   13380 C CG  . ASP C 1 536 ? 125.856 146.944 137.057 1.00 94.75  ? 536 ASP C CG  1 
ATOM   13381 O OD1 . ASP C 1 536 ? 125.208 147.947 136.680 1.00 97.83  ? 536 ASP C OD1 1 
ATOM   13382 O OD2 . ASP C 1 536 ? 126.227 146.079 136.243 1.00 94.88  ? 536 ASP C OD2 1 
ATOM   13383 N N   . LEU C 1 537 ? 126.954 147.870 141.585 1.00 85.98  ? 537 LEU C N   1 
ATOM   13384 C CA  . LEU C 1 537 ? 126.844 147.761 143.040 1.00 86.17  ? 537 LEU C CA  1 
ATOM   13385 C C   . LEU C 1 537 ? 125.988 148.873 143.649 1.00 86.73  ? 537 LEU C C   1 
ATOM   13386 O O   . LEU C 1 537 ? 125.220 148.609 144.564 1.00 91.76  ? 537 LEU C O   1 
ATOM   13387 C CB  . LEU C 1 537 ? 128.227 147.727 143.691 1.00 88.25  ? 537 LEU C CB  1 
ATOM   13388 C CG  . LEU C 1 537 ? 128.993 146.415 143.474 1.00 90.83  ? 537 LEU C CG  1 
ATOM   13389 C CD1 . LEU C 1 537 ? 130.282 146.519 144.269 1.00 87.14  ? 537 LEU C CD1 1 
ATOM   13390 C CD2 . LEU C 1 537 ? 128.241 145.182 143.972 1.00 88.73  ? 537 LEU C CD2 1 
ATOM   13391 N N   . LEU C 1 538 ? 126.021 150.087 143.103 1.00 83.58  ? 538 LEU C N   1 
ATOM   13392 C CA  . LEU C 1 538 ? 125.134 151.177 143.510 1.00 88.19  ? 538 LEU C CA  1 
ATOM   13393 C C   . LEU C 1 538 ? 123.655 150.912 143.159 1.00 84.60  ? 538 LEU C C   1 
ATOM   13394 O O   . LEU C 1 538 ? 122.759 151.505 143.754 1.00 84.06  ? 538 LEU C O   1 
ATOM   13395 C CB  . LEU C 1 538 ? 125.683 152.477 142.891 1.00 89.66  ? 538 LEU C CB  1 
ATOM   13396 C CG  . LEU C 1 538 ? 124.975 153.771 143.313 1.00 89.64  ? 538 LEU C CG  1 
ATOM   13397 C CD1 . LEU C 1 538 ? 125.052 154.004 144.818 1.00 84.51  ? 538 LEU C CD1 1 
ATOM   13398 C CD2 . LEU C 1 538 ? 125.628 154.962 142.621 1.00 87.53  ? 538 LEU C CD2 1 
ATOM   13399 N N   . ARG C 1 539 ? 123.407 149.951 142.248 1.00 79.33  ? 539 ARG C N   1 
ATOM   13400 C CA  . ARG C 1 539 ? 122.006 149.541 141.902 1.00 76.40  ? 539 ARG C CA  1 
ATOM   13401 C C   . ARG C 1 539 ? 121.603 148.401 142.852 1.00 79.54  ? 539 ARG C C   1 
ATOM   13402 O O   . ARG C 1 539 ? 120.480 148.465 143.390 1.00 84.10  ? 539 ARG C O   1 
ATOM   13403 C CB  . ARG C 1 539 ? 121.875 149.248 140.399 1.00 78.41  ? 539 ARG C CB  1 
ATOM   13404 C CG  . ARG C 1 539 ? 122.225 150.479 139.551 1.00 75.92  ? 539 ARG C CG  1 
ATOM   13405 C CD  . ARG C 1 539 ? 121.695 150.392 138.124 1.00 76.05  ? 539 ARG C CD  1 
ATOM   13406 N NE  . ARG C 1 539 ? 122.466 149.512 137.222 1.00 79.62  ? 539 ARG C NE  1 
ATOM   13407 C CZ  . ARG C 1 539 ? 122.128 149.232 135.969 1.00 78.59  ? 539 ARG C CZ  1 
ATOM   13408 N NH1 . ARG C 1 539 ? 122.888 148.429 135.243 1.00 76.30  ? 539 ARG C NH1 1 
ATOM   13409 N NH2 . ARG C 1 539 ? 121.032 149.751 135.445 1.00 79.19  ? 539 ARG C NH2 1 
ATOM   13410 N N   . PHE C 1 540 ? 122.474 147.412 143.060 1.00 81.83  ? 540 PHE C N   1 
ATOM   13411 C CA  . PHE C 1 540 ? 122.273 146.311 144.011 1.00 74.26  ? 540 PHE C CA  1 
ATOM   13412 C C   . PHE C 1 540 ? 122.078 146.816 145.439 1.00 76.00  ? 540 PHE C C   1 
ATOM   13413 O O   . PHE C 1 540 ? 121.250 146.275 146.159 1.00 74.84  ? 540 PHE C O   1 
ATOM   13414 C CB  . PHE C 1 540 ? 123.469 145.346 143.929 1.00 76.38  ? 540 PHE C CB  1 
ATOM   13415 C CG  . PHE C 1 540 ? 123.845 144.622 145.213 1.00 91.80  ? 540 PHE C CG  1 
ATOM   13416 C CD1 . PHE C 1 540 ? 123.120 143.494 145.642 1.00 85.68  ? 540 PHE C CD1 1 
ATOM   13417 C CD2 . PHE C 1 540 ? 124.936 145.080 145.981 1.00 87.27  ? 540 PHE C CD2 1 
ATOM   13418 C CE1 . PHE C 1 540 ? 123.478 142.844 146.841 1.00 78.52  ? 540 PHE C CE1 1 
ATOM   13419 C CE2 . PHE C 1 540 ? 125.283 144.440 147.176 1.00 79.01  ? 540 PHE C CE2 1 
ATOM   13420 C CZ  . PHE C 1 540 ? 124.543 143.318 147.606 1.00 80.15  ? 540 PHE C CZ  1 
ATOM   13421 N N   . LEU C 1 541 ? 122.771 147.884 145.827 1.00 74.81  ? 541 LEU C N   1 
ATOM   13422 C CA  . LEU C 1 541 ? 122.682 148.474 147.156 1.00 72.57  ? 541 LEU C CA  1 
ATOM   13423 C C   . LEU C 1 541 ? 121.257 148.938 147.492 1.00 67.71  ? 541 LEU C C   1 
ATOM   13424 O O   . LEU C 1 541 ? 120.829 148.790 148.625 1.00 75.75  ? 541 LEU C O   1 
ATOM   13425 C CB  . LEU C 1 541 ? 123.710 149.606 147.250 1.00 71.75  ? 541 LEU C CB  1 
ATOM   13426 C CG  . LEU C 1 541 ? 123.832 150.236 148.639 1.00 75.82  ? 541 LEU C CG  1 
ATOM   13427 C CD1 . LEU C 1 541 ? 124.418 149.253 149.648 1.00 72.14  ? 541 LEU C CD1 1 
ATOM   13428 C CD2 . LEU C 1 541 ? 124.731 151.460 148.565 1.00 76.85  ? 541 LEU C CD2 1 
ATOM   13429 N N   . LEU C 1 542 ? 120.479 149.423 146.524 1.00 56.79  ? 542 LEU C N   1 
ATOM   13430 C CA  . LEU C 1 542 ? 119.070 149.751 146.746 1.00 60.41  ? 542 LEU C CA  1 
ATOM   13431 C C   . LEU C 1 542 ? 118.241 148.508 147.100 1.00 61.80  ? 542 LEU C C   1 
ATOM   13432 O O   . LEU C 1 542 ? 117.457 148.532 148.043 1.00 64.97  ? 542 LEU C O   1 
ATOM   13433 C CB  . LEU C 1 542 ? 118.542 150.471 145.491 1.00 71.20  ? 542 LEU C CB  1 
ATOM   13434 C CG  . LEU C 1 542 ? 117.067 150.894 145.558 1.00 73.14  ? 542 LEU C CG  1 
ATOM   13435 C CD1 . LEU C 1 542 ? 116.794 151.910 146.666 1.00 67.64  ? 542 LEU C CD1 1 
ATOM   13436 C CD2 . LEU C 1 542 ? 116.676 151.531 144.234 1.00 60.03  ? 542 LEU C CD2 1 
ATOM   13437 N N   . VAL C 1 543 ? 118.446 147.395 146.393 1.00 66.63  ? 543 VAL C N   1 
ATOM   13438 C CA  . VAL C 1 543 ? 117.760 146.122 146.670 1.00 67.55  ? 543 VAL C CA  1 
ATOM   13439 C C   . VAL C 1 543 ? 118.199 145.542 148.015 1.00 62.46  ? 543 VAL C C   1 
ATOM   13440 O O   . VAL C 1 543 ? 117.364 145.181 148.837 1.00 59.96  ? 543 VAL C O   1 
ATOM   13441 C CB  . VAL C 1 543 ? 117.975 145.094 145.545 1.00 63.58  ? 543 VAL C CB  1 
ATOM   13442 C CG1 . VAL C 1 543 ? 117.036 143.901 145.712 1.00 55.67  ? 543 VAL C CG1 1 
ATOM   13443 C CG2 . VAL C 1 543 ? 117.706 145.688 144.162 1.00 61.64  ? 543 VAL C CG2 1 
ATOM   13444 N N   . TYR C 1 544 ? 119.506 145.527 148.286 1.00 68.60  ? 544 TYR C N   1 
ATOM   13445 C CA  . TYR C 1 544 ? 120.067 145.057 149.542 1.00 61.87  ? 544 TYR C CA  1 
ATOM   13446 C C   . TYR C 1 544 ? 119.621 145.885 150.753 1.00 61.11  ? 544 TYR C C   1 
ATOM   13447 O O   . TYR C 1 544 ? 119.324 145.309 151.793 1.00 65.28  ? 544 TYR C O   1 
ATOM   13448 C CB  . TYR C 1 544 ? 121.598 145.067 149.480 1.00 69.45  ? 544 TYR C CB  1 
ATOM   13449 C CG  . TYR C 1 544 ? 122.260 144.616 150.757 1.00 76.72  ? 544 TYR C CG  1 
ATOM   13450 C CD1 . TYR C 1 544 ? 122.540 145.515 151.774 1.00 75.45  ? 544 TYR C CD1 1 
ATOM   13451 C CD2 . TYR C 1 544 ? 122.589 143.286 150.961 1.00 72.08  ? 544 TYR C CD2 1 
ATOM   13452 C CE1 . TYR C 1 544 ? 123.141 145.107 152.953 1.00 74.41  ? 544 TYR C CE1 1 
ATOM   13453 C CE2 . TYR C 1 544 ? 123.189 142.862 152.135 1.00 66.53  ? 544 TYR C CE2 1 
ATOM   13454 C CZ  . TYR C 1 544 ? 123.467 143.775 153.135 1.00 75.48  ? 544 TYR C CZ  1 
ATOM   13455 O OH  . TYR C 1 544 ? 124.058 143.364 154.294 1.00 78.59  ? 544 TYR C OH  1 
ATOM   13456 N N   . LEU C 1 545 ? 119.522 147.213 150.649 1.00 60.97  ? 545 LEU C N   1 
ATOM   13457 C CA  . LEU C 1 545 ? 119.055 148.069 151.746 1.00 58.63  ? 545 LEU C CA  1 
ATOM   13458 C C   . LEU C 1 545 ? 117.540 148.025 151.974 1.00 54.60  ? 545 LEU C C   1 
ATOM   13459 O O   . LEU C 1 545 ? 117.114 148.179 153.113 1.00 55.11  ? 545 LEU C O   1 
ATOM   13460 C CB  . LEU C 1 545 ? 119.516 149.515 151.527 1.00 56.50  ? 545 LEU C CB  1 
ATOM   13461 C CG  . LEU C 1 545 ? 121.028 149.739 151.669 1.00 65.75  ? 545 LEU C CG  1 
ATOM   13462 C CD1 . LEU C 1 545 ? 121.328 151.203 151.387 1.00 63.24  ? 545 LEU C CD1 1 
ATOM   13463 C CD2 . LEU C 1 545 ? 121.554 149.404 153.058 1.00 66.35  ? 545 LEU C CD2 1 
ATOM   13464 N N   . VAL C 1 546 ? 116.707 147.773 150.963 1.00 65.29  ? 546 VAL C N   1 
ATOM   13465 C CA  . VAL C 1 546 ? 115.275 147.512 151.199 1.00 61.16  ? 546 VAL C CA  1 
ATOM   13466 C C   . VAL C 1 546 ? 115.071 146.168 151.892 1.00 68.30  ? 546 VAL C C   1 
ATOM   13467 O O   . VAL C 1 546 ? 114.263 146.087 152.814 1.00 65.70  ? 546 VAL C O   1 
ATOM   13468 C CB  . VAL C 1 546 ? 114.449 147.613 149.907 1.00 61.18  ? 546 VAL C CB  1 
ATOM   13469 C CG1 . VAL C 1 546 ? 113.004 147.166 150.125 1.00 57.53  ? 546 VAL C CG1 1 
ATOM   13470 C CG2 . VAL C 1 546 ? 114.400 149.062 149.419 1.00 65.16  ? 546 VAL C CG2 1 
ATOM   13471 N N   . PHE C 1 547 ? 115.832 145.128 151.533 1.00 77.33  ? 547 PHE C N   1 
ATOM   13472 C CA  . PHE C 1 547 ? 115.852 143.881 152.297 1.00 66.38  ? 547 PHE C CA  1 
ATOM   13473 C C   . PHE C 1 547 ? 116.328 144.137 153.728 1.00 68.87  ? 547 PHE C C   1 
ATOM   13474 O O   . PHE C 1 547 ? 115.610 143.838 154.676 1.00 77.65  ? 547 PHE C O   1 
ATOM   13475 C CB  . PHE C 1 547 ? 116.766 142.838 151.637 1.00 68.07  ? 547 PHE C CB  1 
ATOM   13476 C CG  . PHE C 1 547 ? 116.290 142.125 150.385 1.00 74.86  ? 547 PHE C CG  1 
ATOM   13477 C CD1 . PHE C 1 547 ? 115.154 142.525 149.660 1.00 71.03  ? 547 PHE C CD1 1 
ATOM   13478 C CD2 . PHE C 1 547 ? 117.021 141.004 149.950 1.00 75.46  ? 547 PHE C CD2 1 
ATOM   13479 C CE1 . PHE C 1 547 ? 114.736 141.793 148.538 1.00 73.22  ? 547 PHE C CE1 1 
ATOM   13480 C CE2 . PHE C 1 547 ? 116.611 140.288 148.817 1.00 77.28  ? 547 PHE C CE2 1 
ATOM   13481 C CZ  . PHE C 1 547 ? 115.467 140.673 148.112 1.00 70.36  ? 547 PHE C CZ  1 
ATOM   13482 N N   . LEU C 1 548 ? 117.511 144.719 153.907 1.00 62.91  ? 548 LEU C N   1 
ATOM   13483 C CA  . LEU C 1 548 ? 118.125 144.899 155.217 1.00 60.98  ? 548 LEU C CA  1 
ATOM   13484 C C   . LEU C 1 548 ? 117.257 145.733 156.163 1.00 64.14  ? 548 LEU C C   1 
ATOM   13485 O O   . LEU C 1 548 ? 116.993 145.295 157.275 1.00 72.05  ? 548 LEU C O   1 
ATOM   13486 C CB  . LEU C 1 548 ? 119.533 145.487 155.023 1.00 65.40  ? 548 LEU C CB  1 
ATOM   13487 C CG  . LEU C 1 548 ? 120.315 145.697 156.324 1.00 58.48  ? 548 LEU C CG  1 
ATOM   13488 C CD1 . LEU C 1 548 ? 120.596 144.376 157.012 1.00 64.99  ? 548 LEU C CD1 1 
ATOM   13489 C CD2 . LEU C 1 548 ? 121.647 146.363 156.030 1.00 61.73  ? 548 LEU C CD2 1 
ATOM   13490 N N   . PHE C 1 549 ? 116.760 146.897 155.744 1.00 67.92  ? 549 PHE C N   1 
ATOM   13491 C CA  . PHE C 1 549 ? 115.867 147.692 156.585 1.00 63.42  ? 549 PHE C CA  1 
ATOM   13492 C C   . PHE C 1 549 ? 114.510 147.007 156.796 1.00 67.26  ? 549 PHE C C   1 
ATOM   13493 O O   . PHE C 1 549 ? 114.026 146.971 157.921 1.00 63.99  ? 549 PHE C O   1 
ATOM   13494 C CB  . PHE C 1 549 ? 115.700 149.089 155.984 1.00 67.57  ? 549 PHE C CB  1 
ATOM   13495 C CG  . PHE C 1 549 ? 114.810 149.999 156.804 1.00 76.26  ? 549 PHE C CG  1 
ATOM   13496 C CD1 . PHE C 1 549 ? 115.317 150.607 157.967 1.00 78.84  ? 549 PHE C CD1 1 
ATOM   13497 C CD2 . PHE C 1 549 ? 113.474 150.235 156.427 1.00 69.40  ? 549 PHE C CD2 1 
ATOM   13498 C CE1 . PHE C 1 549 ? 114.499 151.447 158.742 1.00 71.76  ? 549 PHE C CE1 1 
ATOM   13499 C CE2 . PHE C 1 549 ? 112.660 151.073 157.205 1.00 70.30  ? 549 PHE C CE2 1 
ATOM   13500 C CZ  . PHE C 1 549 ? 113.169 151.679 158.361 1.00 70.00  ? 549 PHE C CZ  1 
ATOM   13501 N N   . GLY C 1 550 ? 113.916 146.409 155.760 1.00 72.70  ? 550 GLY C N   1 
ATOM   13502 C CA  . GLY C 1 550 ? 112.620 145.739 155.857 1.00 69.55  ? 550 GLY C CA  1 
ATOM   13503 C C   . GLY C 1 550 ? 112.604 144.595 156.869 1.00 74.92  ? 550 GLY C C   1 
ATOM   13504 O O   . GLY C 1 550 ? 111.655 144.476 157.642 1.00 74.15  ? 550 GLY C O   1 
ATOM   13505 N N   . PHE C 1 551 ? 113.667 143.787 156.912 1.00 63.50  ? 551 PHE C N   1 
ATOM   13506 C CA  . PHE C 1 551 ? 113.847 142.738 157.913 1.00 55.31  ? 551 PHE C CA  1 
ATOM   13507 C C   . PHE C 1 551 ? 114.319 143.278 159.274 1.00 68.14  ? 551 PHE C C   1 
ATOM   13508 O O   . PHE C 1 551 ? 113.915 142.732 160.297 1.00 72.43  ? 551 PHE C O   1 
ATOM   13509 C CB  . PHE C 1 551 ? 114.791 141.668 157.365 1.00 57.80  ? 551 PHE C CB  1 
ATOM   13510 C CG  . PHE C 1 551 ? 114.126 140.665 156.440 1.00 58.10  ? 551 PHE C CG  1 
ATOM   13511 C CD1 . PHE C 1 551 ? 113.467 139.557 156.995 1.00 65.17  ? 551 PHE C CD1 1 
ATOM   13512 C CD2 . PHE C 1 551 ? 114.193 140.794 155.041 1.00 58.78  ? 551 PHE C CD2 1 
ATOM   13513 C CE1 . PHE C 1 551 ? 112.867 138.600 156.165 1.00 66.71  ? 551 PHE C CE1 1 
ATOM   13514 C CE2 . PHE C 1 551 ? 113.606 139.828 154.210 1.00 59.33  ? 551 PHE C CE2 1 
ATOM   13515 C CZ  . PHE C 1 551 ? 112.934 138.736 154.771 1.00 62.94  ? 551 PHE C CZ  1 
ATOM   13516 N N   . ALA C 1 552 ? 115.106 144.357 159.351 1.00 65.89  ? 552 ALA C N   1 
ATOM   13517 C CA  . ALA C 1 552 ? 115.545 144.934 160.621 1.00 58.06  ? 552 ALA C CA  1 
ATOM   13518 C C   . ALA C 1 552 ? 114.388 145.501 161.452 1.00 63.76  ? 552 ALA C C   1 
ATOM   13519 O O   . ALA C 1 552 ? 114.264 145.164 162.627 1.00 67.33  ? 552 ALA C O   1 
ATOM   13520 C CB  . ALA C 1 552 ? 116.602 146.008 160.368 1.00 64.12  ? 552 ALA C CB  1 
ATOM   13521 N N   . VAL C 1 553 ? 113.491 146.306 160.873 1.00 73.55  ? 553 VAL C N   1 
ATOM   13522 C CA  . VAL C 1 553 ? 112.315 146.815 161.607 1.00 67.76  ? 553 VAL C CA  1 
ATOM   13523 C C   . VAL C 1 553 ? 111.397 145.682 162.076 1.00 70.82  ? 553 VAL C C   1 
ATOM   13524 O O   . VAL C 1 553 ? 110.694 145.817 163.073 1.00 72.52  ? 553 VAL C O   1 
ATOM   13525 C CB  . VAL C 1 553 ? 111.500 147.840 160.794 1.00 65.11  ? 553 VAL C CB  1 
ATOM   13526 C CG1 . VAL C 1 553 ? 112.306 149.106 160.529 1.00 66.18  ? 553 VAL C CG1 1 
ATOM   13527 C CG2 . VAL C 1 553 ? 110.970 147.330 159.453 1.00 67.05  ? 553 VAL C CG2 1 
ATOM   13528 N N   . ALA C 1 554 ? 111.413 144.544 161.391 1.00 69.96  ? 554 ALA C N   1 
ATOM   13529 C CA  . ALA C 1 554 ? 110.596 143.383 161.686 1.00 64.91  ? 554 ALA C CA  1 
ATOM   13530 C C   . ALA C 1 554 ? 111.155 142.539 162.828 1.00 72.00  ? 554 ALA C C   1 
ATOM   13531 O O   . ALA C 1 554 ? 110.442 142.251 163.783 1.00 76.31  ? 554 ALA C O   1 
ATOM   13532 C CB  . ALA C 1 554 ? 110.489 142.593 160.394 1.00 63.47  ? 554 ALA C CB  1 
ATOM   13533 N N   . LEU C 1 555 ? 112.439 142.187 162.780 1.00 80.52  ? 555 LEU C N   1 
ATOM   13534 C CA  . LEU C 1 555 ? 113.096 141.450 163.860 1.00 75.29  ? 555 LEU C CA  1 
ATOM   13535 C C   . LEU C 1 555 ? 113.113 142.252 165.158 1.00 74.63  ? 555 LEU C C   1 
ATOM   13536 O O   . LEU C 1 555 ? 112.890 141.665 166.211 1.00 77.83  ? 555 LEU C O   1 
ATOM   13537 C CB  . LEU C 1 555 ? 114.514 141.064 163.431 1.00 73.49  ? 555 LEU C CB  1 
ATOM   13538 C CG  . LEU C 1 555 ? 114.508 139.913 162.418 1.00 77.37  ? 555 LEU C CG  1 
ATOM   13539 C CD1 . LEU C 1 555 ? 115.819 139.889 161.667 1.00 80.50  ? 555 LEU C CD1 1 
ATOM   13540 C CD2 . LEU C 1 555 ? 114.352 138.562 163.104 1.00 76.97  ? 555 LEU C CD2 1 
ATOM   13541 N N   . VAL C 1 556 ? 113.289 143.573 165.104 1.00 73.70  ? 556 VAL C N   1 
ATOM   13542 C CA  . VAL C 1 556 ? 113.170 144.452 166.280 1.00 69.11  ? 556 VAL C CA  1 
ATOM   13543 C C   . VAL C 1 556 ? 111.761 144.444 166.868 1.00 78.11  ? 556 VAL C C   1 
ATOM   13544 O O   . VAL C 1 556 ? 111.598 144.333 168.075 1.00 83.15  ? 556 VAL C O   1 
ATOM   13545 C CB  . VAL C 1 556 ? 113.583 145.886 165.918 1.00 75.27  ? 556 VAL C CB  1 
ATOM   13546 C CG1 . VAL C 1 556 ? 113.311 146.905 167.018 1.00 75.39  ? 556 VAL C CG1 1 
ATOM   13547 C CG2 . VAL C 1 556 ? 115.077 145.920 165.643 1.00 82.31  ? 556 VAL C CG2 1 
ATOM   13548 N N   . SER C 1 557 ? 110.727 144.520 166.029 1.00 85.43  ? 557 SER C N   1 
ATOM   13549 C CA  . SER C 1 557 ? 109.329 144.514 166.471 1.00 80.67  ? 557 SER C CA  1 
ATOM   13550 C C   . SER C 1 557 ? 108.924 143.194 167.122 1.00 79.59  ? 557 SER C C   1 
ATOM   13551 O O   . SER C 1 557 ? 108.174 143.195 168.090 1.00 78.40  ? 557 SER C O   1 
ATOM   13552 C CB  . SER C 1 557 ? 108.409 144.795 165.286 1.00 78.82  ? 557 SER C CB  1 
ATOM   13553 O OG  . SER C 1 557 ? 108.694 146.064 164.741 1.00 78.06  ? 557 SER C OG  1 
ATOM   13554 N N   . LEU C 1 558 ? 109.428 142.066 166.620 1.00 80.65  ? 558 LEU C N   1 
ATOM   13555 C CA  . LEU C 1 558 ? 109.060 140.734 167.090 1.00 77.52  ? 558 LEU C CA  1 
ATOM   13556 C C   . LEU C 1 558 ? 109.914 140.224 168.263 1.00 84.88  ? 558 LEU C C   1 
ATOM   13557 O O   . LEU C 1 558 ? 109.421 139.506 169.127 1.00 86.63  ? 558 LEU C O   1 
ATOM   13558 C CB  . LEU C 1 558 ? 109.142 139.799 165.880 1.00 71.01  ? 558 LEU C CB  1 
ATOM   13559 C CG  . LEU C 1 558 ? 108.351 138.502 166.018 1.00 81.43  ? 558 LEU C CG  1 
ATOM   13560 C CD1 . LEU C 1 558 ? 106.853 138.729 166.202 1.00 78.60  ? 558 LEU C CD1 1 
ATOM   13561 C CD2 . LEU C 1 558 ? 108.523 137.704 164.741 1.00 80.41  ? 558 LEU C CD2 1 
ATOM   13562 N N   . SER C 1 559 ? 111.185 140.629 168.339 1.00 88.53  ? 559 SER C N   1 
ATOM   13563 C CA  . SER C 1 559 ? 112.088 140.280 169.449 1.00 86.88  ? 559 SER C CA  1 
ATOM   13564 C C   . SER C 1 559 ? 111.833 141.082 170.732 1.00 93.63  ? 559 SER C C   1 
ATOM   13565 O O   . SER C 1 559 ? 112.551 140.923 171.719 1.00 95.76  ? 559 SER C O   1 
ATOM   13566 C CB  . SER C 1 559 ? 113.552 140.447 169.046 1.00 90.61  ? 559 SER C CB  1 
ATOM   13567 O OG  . SER C 1 559 ? 113.809 139.754 167.846 1.00 94.97  ? 559 SER C OG  1 
ATOM   13568 N N   . ARG C 1 560 ? 110.828 141.962 170.740 1.00 99.54  ? 560 ARG C N   1 
ATOM   13569 C CA  . ARG C 1 560 ? 110.446 142.791 171.889 1.00 99.51  ? 560 ARG C CA  1 
ATOM   13570 C C   . ARG C 1 560 ? 109.755 142.005 173.013 1.00 99.95  ? 560 ARG C C   1 
ATOM   13571 O O   . ARG C 1 560 ? 109.807 142.425 174.166 1.00 97.44  ? 560 ARG C O   1 
ATOM   13572 C CB  . ARG C 1 560 ? 109.569 143.928 171.346 1.00 101.03 ? 560 ARG C CB  1 
ATOM   13573 C CG  . ARG C 1 560 ? 109.479 145.126 172.297 1.00 100.93 ? 560 ARG C CG  1 
ATOM   13574 C CD  . ARG C 1 560 ? 108.583 146.234 171.727 1.00 101.54 ? 560 ARG C CD  1 
ATOM   13575 N NE  . ARG C 1 560 ? 109.103 146.801 170.468 1.00 101.57 ? 560 ARG C NE  1 
ATOM   13576 C CZ  . ARG C 1 560 ? 110.010 147.748 170.344 1.00 99.82  ? 560 ARG C CZ  1 
ATOM   13577 N NH1 . ARG C 1 560 ? 110.354 148.190 169.172 1.00 96.21  ? 560 ARG C NH1 1 
ATOM   13578 N NH2 . ARG C 1 560 ? 110.585 148.290 171.370 1.00 100.21 ? 560 ARG C NH2 1 
ATOM   13579 N N   . GLU C 1 561 ? 109.146 140.855 172.716 1.00 112.16 ? 561 GLU C N   1 
ATOM   13580 C CA  . GLU C 1 561 ? 108.363 140.068 173.682 1.00 115.04 ? 561 GLU C CA  1 
ATOM   13581 C C   . GLU C 1 561 ? 109.141 138.848 174.216 1.00 112.99 ? 561 GLU C C   1 
ATOM   13582 O O   . GLU C 1 561 ? 109.579 137.986 173.454 1.00 109.01 ? 561 GLU C O   1 
ATOM   13583 C CB  . GLU C 1 561 ? 107.032 139.612 173.047 1.00 114.67 ? 561 GLU C CB  1 
ATOM   13584 C CG  . GLU C 1 561 ? 106.147 140.746 172.508 1.00 111.78 ? 561 GLU C CG  1 
ATOM   13585 C CD  . GLU C 1 561 ? 105.944 141.898 173.507 1.00 115.59 ? 561 GLU C CD  1 
ATOM   13586 O OE1 . GLU C 1 561 ? 105.502 141.641 174.651 1.00 112.12 ? 561 GLU C OE1 1 
ATOM   13587 O OE2 . GLU C 1 561 ? 106.231 143.058 173.140 1.00 116.81 ? 561 GLU C OE2 1 
ATOM   13588 N N   . ALA C 1 562 ? 109.270 138.743 175.541 1.00 114.38 ? 562 ALA C N   1 
ATOM   13589 C CA  . ALA C 1 562 ? 109.855 137.594 176.239 1.00 115.32 ? 562 ALA C CA  1 
ATOM   13590 C C   . ALA C 1 562 ? 108.822 136.483 176.520 1.00 117.00 ? 562 ALA C C   1 
ATOM   13591 O O   . ALA C 1 562 ? 107.619 136.741 176.628 1.00 117.39 ? 562 ALA C O   1 
ATOM   13592 C CB  . ALA C 1 562 ? 110.518 138.095 177.521 1.00 110.72 ? 562 ALA C CB  1 
ATOM   13593 N N   . ARG C 1 563 ? 109.275 135.233 176.631 1.00 111.73 ? 563 ARG C N   1 
ATOM   13594 C CA  . ARG C 1 563 ? 108.420 134.051 176.764 1.00 111.25 ? 563 ARG C CA  1 
ATOM   13595 C C   . ARG C 1 563 ? 107.695 133.975 178.113 1.00 109.78 ? 563 ARG C C   1 
ATOM   13596 O O   . ARG C 1 563 ? 108.236 133.511 179.118 1.00 111.67 ? 563 ARG C O   1 
ATOM   13597 C CB  . ARG C 1 563 ? 109.257 132.800 176.505 1.00 107.83 ? 563 ARG C CB  1 
ATOM   13598 N N   . PRO C 1 589 ? 120.823 140.381 170.934 1.00 113.02 ? 589 PRO C N   1 
ATOM   13599 C CA  . PRO C 1 589 ? 120.489 140.809 169.585 1.00 112.47 ? 589 PRO C CA  1 
ATOM   13600 C C   . PRO C 1 589 ? 119.144 141.540 169.455 1.00 110.98 ? 589 PRO C C   1 
ATOM   13601 O O   . PRO C 1 589 ? 118.272 141.454 170.322 1.00 105.95 ? 589 PRO C O   1 
ATOM   13602 C CB  . PRO C 1 589 ? 120.526 139.525 168.753 1.00 112.55 ? 589 PRO C CB  1 
ATOM   13603 C CG  . PRO C 1 589 ? 121.612 138.712 169.441 1.00 108.68 ? 589 PRO C CG  1 
ATOM   13604 C CD  . PRO C 1 589 ? 121.387 139.048 170.911 1.00 111.28 ? 589 PRO C CD  1 
ATOM   13605 N N   . TYR C 1 590 ? 118.968 142.236 168.327 1.00 105.98 ? 590 TYR C N   1 
ATOM   13606 C CA  . TYR C 1 590 ? 117.701 142.833 167.868 1.00 103.67 ? 590 TYR C CA  1 
ATOM   13607 C C   . TYR C 1 590 ? 117.066 143.863 168.823 1.00 99.99  ? 590 TYR C C   1 
ATOM   13608 O O   . TYR C 1 590 ? 115.852 144.036 168.839 1.00 97.79  ? 590 TYR C O   1 
ATOM   13609 C CB  . TYR C 1 590 ? 116.680 141.726 167.586 1.00 100.81 ? 590 TYR C CB  1 
ATOM   13610 C CG  . TYR C 1 590 ? 117.240 140.543 166.840 1.00 101.34 ? 590 TYR C CG  1 
ATOM   13611 C CD1 . TYR C 1 590 ? 117.643 140.657 165.520 1.00 101.38 ? 590 TYR C CD1 1 
ATOM   13612 C CD2 . TYR C 1 590 ? 117.375 139.309 167.454 1.00 99.35  ? 590 TYR C CD2 1 
ATOM   13613 C CE1 . TYR C 1 590 ? 118.165 139.577 164.828 1.00 102.83 ? 590 TYR C CE1 1 
ATOM   13614 C CE2 . TYR C 1 590 ? 117.894 138.219 166.778 1.00 100.41 ? 590 TYR C CE2 1 
ATOM   13615 C CZ  . TYR C 1 590 ? 118.290 138.353 165.460 1.00 103.77 ? 590 TYR C CZ  1 
ATOM   13616 O OH  . TYR C 1 590 ? 118.804 137.283 164.788 1.00 102.97 ? 590 TYR C OH  1 
ATOM   13617 N N   . ARG C 1 591 ? 117.876 144.570 169.615 1.00 103.48 ? 591 ARG C N   1 
ATOM   13618 C CA  . ARG C 1 591 ? 117.409 145.576 170.572 1.00 104.14 ? 591 ARG C CA  1 
ATOM   13619 C C   . ARG C 1 591 ? 116.987 146.910 169.938 1.00 103.67 ? 591 ARG C C   1 
ATOM   13620 O O   . ARG C 1 591 ? 116.171 147.637 170.504 1.00 103.73 ? 591 ARG C O   1 
ATOM   13621 C CB  . ARG C 1 591 ? 118.528 145.829 171.574 1.00 98.86  ? 591 ARG C CB  1 
ATOM   13622 N N   . SER C 1 592 ? 117.534 147.254 168.770 1.00 91.79  ? 592 SER C N   1 
ATOM   13623 C CA  . SER C 1 592 ? 117.308 148.531 168.080 1.00 92.93  ? 592 SER C CA  1 
ATOM   13624 C C   . SER C 1 592 ? 117.465 148.376 166.569 1.00 91.19  ? 592 SER C C   1 
ATOM   13625 O O   . SER C 1 592 ? 118.007 147.376 166.103 1.00 91.10  ? 592 SER C O   1 
ATOM   13626 C CB  . SER C 1 592 ? 118.260 149.616 168.607 1.00 94.20  ? 592 SER C CB  1 
ATOM   13627 O OG  . SER C 1 592 ? 119.564 149.492 168.071 1.00 98.00  ? 592 SER C OG  1 
ATOM   13628 N N   . ILE C 1 593 ? 117.016 149.355 165.778 1.00 90.67  ? 593 ILE C N   1 
ATOM   13629 C CA  . ILE C 1 593 ? 117.146 149.312 164.312 1.00 90.67  ? 593 ILE C CA  1 
ATOM   13630 C C   . ILE C 1 593 ? 118.617 149.222 163.890 1.00 89.85  ? 593 ILE C C   1 
ATOM   13631 O O   . ILE C 1 593 ? 118.939 148.479 162.965 1.00 92.66  ? 593 ILE C O   1 
ATOM   13632 C CB  . ILE C 1 593 ? 116.471 150.531 163.638 1.00 92.36  ? 593 ILE C CB  1 
ATOM   13633 C CG1 . ILE C 1 593 ? 115.018 150.792 164.086 1.00 91.13  ? 593 ILE C CG1 1 
ATOM   13634 C CG2 . ILE C 1 593 ? 116.523 150.391 162.109 1.00 87.30  ? 593 ILE C CG2 1 
ATOM   13635 C CD1 . ILE C 1 593 ? 114.075 149.601 163.936 1.00 91.58  ? 593 ILE C CD1 1 
ATOM   13636 N N   . LEU C 1 594 ? 119.518 149.930 164.579 1.00 87.34  ? 594 LEU C N   1 
ATOM   13637 C CA  . LEU C 1 594 ? 120.959 149.874 164.335 1.00 90.86  ? 594 LEU C CA  1 
ATOM   13638 C C   . LEU C 1 594 ? 121.518 148.483 164.647 1.00 92.67  ? 594 LEU C C   1 
ATOM   13639 O O   . LEU C 1 594 ? 122.173 147.889 163.799 1.00 96.34  ? 594 LEU C O   1 
ATOM   13640 C CB  . LEU C 1 594 ? 121.651 150.975 165.160 1.00 95.30  ? 594 LEU C CB  1 
ATOM   13641 C CG  . LEU C 1 594 ? 123.191 150.939 165.127 1.00 96.66  ? 594 LEU C CG  1 
ATOM   13642 C CD1 . LEU C 1 594 ? 123.755 151.101 163.720 1.00 91.56  ? 594 LEU C CD1 1 
ATOM   13643 C CD2 . LEU C 1 594 ? 123.743 152.058 166.004 1.00 91.87  ? 594 LEU C CD2 1 
ATOM   13644 N N   . ASP C 1 595 ? 121.227 147.939 165.828 1.00 87.55  ? 595 ASP C N   1 
ATOM   13645 C CA  . ASP C 1 595 ? 121.724 146.622 166.229 1.00 85.20  ? 595 ASP C CA  1 
ATOM   13646 C C   . ASP C 1 595 ? 121.201 145.501 165.329 1.00 89.27  ? 595 ASP C C   1 
ATOM   13647 O O   . ASP C 1 595 ? 121.975 144.649 164.915 1.00 92.26  ? 595 ASP C O   1 
ATOM   13648 C CB  . ASP C 1 595 ? 121.358 146.337 167.689 1.00 94.94  ? 595 ASP C CB  1 
ATOM   13649 C CG  . ASP C 1 595 ? 121.937 147.371 168.652 1.00 101.45 ? 595 ASP C CG  1 
ATOM   13650 O OD1 . ASP C 1 595 ? 123.163 147.608 168.621 1.00 96.51  ? 595 ASP C OD1 1 
ATOM   13651 O OD2 . ASP C 1 595 ? 121.147 147.959 169.427 1.00 102.93 ? 595 ASP C OD2 1 
ATOM   13652 N N   . ALA C 1 596 ? 119.918 145.506 164.963 1.00 87.25  ? 596 ALA C N   1 
ATOM   13653 C CA  . ALA C 1 596 ? 119.363 144.540 164.021 1.00 80.05  ? 596 ALA C CA  1 
ATOM   13654 C C   . ALA C 1 596 ? 119.922 144.714 162.605 1.00 79.86  ? 596 ALA C C   1 
ATOM   13655 O O   . ALA C 1 596 ? 120.249 143.725 161.969 1.00 85.49  ? 596 ALA C O   1 
ATOM   13656 C CB  . ALA C 1 596 ? 117.846 144.650 164.036 1.00 78.13  ? 596 ALA C CB  1 
ATOM   13657 N N   . SER C 1 597 ? 120.119 145.942 162.122 1.00 80.04  ? 597 SER C N   1 
ATOM   13658 C CA  . SER C 1 597 ? 120.802 146.179 160.845 1.00 72.13  ? 597 SER C CA  1 
ATOM   13659 C C   . SER C 1 597 ? 122.230 145.653 160.869 1.00 73.22  ? 597 SER C C   1 
ATOM   13660 O O   . SER C 1 597 ? 122.692 145.114 159.875 1.00 81.98  ? 597 SER C O   1 
ATOM   13661 C CB  . SER C 1 597 ? 120.847 147.668 160.491 1.00 78.38  ? 597 SER C CB  1 
ATOM   13662 O OG  . SER C 1 597 ? 119.548 148.208 160.376 1.00 86.22  ? 597 SER C OG  1 
ATOM   13663 N N   . LEU C 1 598 ? 122.938 145.761 161.995 1.00 77.79  ? 598 LEU C N   1 
ATOM   13664 C CA  . LEU C 1 598 ? 124.301 145.268 162.128 1.00 80.55  ? 598 LEU C CA  1 
ATOM   13665 C C   . LEU C 1 598 ? 124.370 143.740 162.255 1.00 81.77  ? 598 LEU C C   1 
ATOM   13666 O O   . LEU C 1 598 ? 125.190 143.115 161.596 1.00 90.73  ? 598 LEU C O   1 
ATOM   13667 C CB  . LEU C 1 598 ? 124.964 146.003 163.300 1.00 76.49  ? 598 LEU C CB  1 
ATOM   13668 C CG  . LEU C 1 598 ? 126.486 145.845 163.332 1.00 83.69  ? 598 LEU C CG  1 
ATOM   13669 C CD1 . LEU C 1 598 ? 127.149 146.511 162.128 1.00 82.50  ? 598 LEU C CD1 1 
ATOM   13670 C CD2 . LEU C 1 598 ? 127.034 146.483 164.600 1.00 80.72  ? 598 LEU C CD2 1 
ATOM   13671 N N   . GLU C 1 599 ? 123.492 143.106 163.026 1.00 74.09  ? 599 GLU C N   1 
ATOM   13672 C CA  . GLU C 1 599 ? 123.386 141.644 163.106 1.00 68.33  ? 599 GLU C CA  1 
ATOM   13673 C C   . GLU C 1 599 ? 122.982 141.018 161.770 1.00 71.42  ? 599 GLU C C   1 
ATOM   13674 O O   . GLU C 1 599 ? 123.572 140.028 161.347 1.00 75.44  ? 599 GLU C O   1 
ATOM   13675 C CB  . GLU C 1 599 ? 122.371 141.247 164.189 1.00 78.34  ? 599 GLU C CB  1 
ATOM   13676 C CG  . GLU C 1 599 ? 122.837 141.503 165.631 1.00 82.84  ? 599 GLU C CG  1 
ATOM   13677 C CD  . GLU C 1 599 ? 124.177 140.838 165.980 1.00 84.59  ? 599 GLU C CD  1 
ATOM   13678 O OE1 . GLU C 1 599 ? 124.428 139.710 165.524 1.00 82.39  ? 599 GLU C OE1 1 
ATOM   13679 O OE2 . GLU C 1 599 ? 125.005 141.463 166.682 1.00 82.64  ? 599 GLU C OE2 1 
ATOM   13680 N N   . LEU C 1 600 ? 122.022 141.612 161.058 1.00 63.30  ? 600 LEU C N   1 
ATOM   13681 C CA  . LEU C 1 600 ? 121.672 141.214 159.699 1.00 51.34  ? 600 LEU C CA  1 
ATOM   13682 C C   . LEU C 1 600 ? 122.775 141.531 158.694 1.00 42.46  ? 600 LEU C C   1 
ATOM   13683 O O   . LEU C 1 600 ? 122.932 140.798 157.723 1.00 51.92  ? 600 LEU C O   1 
ATOM   13684 C CB  . LEU C 1 600 ? 120.391 141.921 159.260 1.00 64.09  ? 600 LEU C CB  1 
ATOM   13685 C CG  . LEU C 1 600 ? 119.086 141.470 159.918 1.00 53.68  ? 600 LEU C CG  1 
ATOM   13686 C CD1 . LEU C 1 600 ? 117.964 142.257 159.255 1.00 58.16  ? 600 LEU C CD1 1 
ATOM   13687 C CD2 . LEU C 1 600 ? 118.834 139.988 159.703 1.00 57.26  ? 600 LEU C CD2 1 
ATOM   13688 N N   . PHE C 1 601 ? 123.561 142.592 158.877 1.00 57.21  ? 601 PHE C N   1 
ATOM   13689 C CA  . PHE C 1 601 ? 124.685 142.839 157.980 1.00 62.58  ? 601 PHE C CA  1 
ATOM   13690 C C   . PHE C 1 601 ? 125.800 141.812 158.198 1.00 71.73  ? 601 PHE C C   1 
ATOM   13691 O O   . PHE C 1 601 ? 126.369 141.315 157.229 1.00 67.31  ? 601 PHE C O   1 
ATOM   13692 C CB  . PHE C 1 601 ? 125.216 144.265 158.133 1.00 60.29  ? 601 PHE C CB  1 
ATOM   13693 C CG  . PHE C 1 601 ? 126.414 144.522 157.247 1.00 67.25  ? 601 PHE C CG  1 
ATOM   13694 C CD1 . PHE C 1 601 ? 126.238 144.708 155.865 1.00 67.56  ? 601 PHE C CD1 1 
ATOM   13695 C CD2 . PHE C 1 601 ? 127.717 144.482 157.780 1.00 73.35  ? 601 PHE C CD2 1 
ATOM   13696 C CE1 . PHE C 1 601 ? 127.354 144.845 155.024 1.00 68.06  ? 601 PHE C CE1 1 
ATOM   13697 C CE2 . PHE C 1 601 ? 128.830 144.618 156.940 1.00 66.49  ? 601 PHE C CE2 1 
ATOM   13698 C CZ  . PHE C 1 601 ? 128.650 144.792 155.558 1.00 67.07  ? 601 PHE C CZ  1 
ATOM   13699 N N   . LYS C 1 602 ? 126.053 141.381 159.436 1.00 78.66  ? 602 LYS C N   1 
ATOM   13700 C CA  . LYS C 1 602 ? 127.071 140.377 159.726 1.00 54.48  ? 602 LYS C CA  1 
ATOM   13701 C C   . LYS C 1 602 ? 126.904 139.072 158.954 1.00 51.26  ? 602 LYS C C   1 
ATOM   13702 O O   . LYS C 1 602 ? 127.905 138.439 158.646 1.00 70.64  ? 602 LYS C O   1 
ATOM   13703 C CB  . LYS C 1 602 ? 127.165 140.123 161.228 1.00 61.47  ? 602 LYS C CB  1 
ATOM   13704 C CG  . LYS C 1 602 ? 128.092 141.134 161.901 1.00 62.44  ? 602 LYS C CG  1 
ATOM   13705 C CD  . LYS C 1 602 ? 128.402 140.741 163.348 1.00 62.42  ? 602 LYS C CD  1 
ATOM   13706 C CE  . LYS C 1 602 ? 127.224 141.074 164.257 1.00 70.18  ? 602 LYS C CE  1 
ATOM   13707 N NZ  . LYS C 1 602 ? 127.475 140.693 165.663 1.00 75.82  ? 602 LYS C NZ  1 
ATOM   13708 N N   . PHE C 1 603 ? 125.706 138.688 158.516 1.00 66.12  ? 603 PHE C N   1 
ATOM   13709 C CA  . PHE C 1 603 ? 125.497 137.523 157.637 1.00 71.80  ? 603 PHE C CA  1 
ATOM   13710 C C   . PHE C 1 603 ? 126.211 137.601 156.282 1.00 71.13  ? 603 PHE C C   1 
ATOM   13711 O O   . PHE C 1 603 ? 126.479 136.564 155.684 1.00 73.97  ? 603 PHE C O   1 
ATOM   13712 C CB  . PHE C 1 603 ? 124.009 137.342 157.350 1.00 65.53  ? 603 PHE C CB  1 
ATOM   13713 C CG  . PHE C 1 603 ? 123.246 136.636 158.440 1.00 67.28  ? 603 PHE C CG  1 
ATOM   13714 C CD1 . PHE C 1 603 ? 123.187 135.237 158.444 1.00 65.03  ? 603 PHE C CD1 1 
ATOM   13715 C CD2 . PHE C 1 603 ? 122.597 137.369 159.441 1.00 67.75  ? 603 PHE C CD2 1 
ATOM   13716 C CE1 . PHE C 1 603 ? 122.444 134.571 159.428 1.00 63.33  ? 603 PHE C CE1 1 
ATOM   13717 C CE2 . PHE C 1 603 ? 121.855 136.701 160.430 1.00 66.60  ? 603 PHE C CE2 1 
ATOM   13718 C CZ  . PHE C 1 603 ? 121.775 135.307 160.420 1.00 66.74  ? 603 PHE C CZ  1 
ATOM   13719 N N   . THR C 1 604 ? 126.505 138.795 155.775 1.00 70.57  ? 604 THR C N   1 
ATOM   13720 C CA  . THR C 1 604 ? 127.209 138.959 154.495 1.00 63.22  ? 604 THR C CA  1 
ATOM   13721 C C   . THR C 1 604 ? 128.726 138.879 154.646 1.00 75.92  ? 604 THR C C   1 
ATOM   13722 O O   . THR C 1 604 ? 129.399 138.490 153.696 1.00 78.60  ? 604 THR C O   1 
ATOM   13723 C CB  . THR C 1 604 ? 126.831 140.260 153.794 1.00 63.29  ? 604 THR C CB  1 
ATOM   13724 O OG1 . THR C 1 604 ? 127.237 141.378 154.539 1.00 67.46  ? 604 THR C OG1 1 
ATOM   13725 C CG2 . THR C 1 604 ? 125.336 140.358 153.547 1.00 75.10  ? 604 THR C CG2 1 
ATOM   13726 N N   . ILE C 1 605 ? 129.277 139.167 155.837 1.00 74.54  ? 605 ILE C N   1 
ATOM   13727 C CA  . ILE C 1 605 ? 130.705 138.947 156.134 1.00 64.19  ? 605 ILE C CA  1 
ATOM   13728 C C   . ILE C 1 605 ? 131.011 137.532 156.674 1.00 63.45  ? 605 ILE C C   1 
ATOM   13729 O O   . ILE C 1 605 ? 132.143 137.255 157.050 1.00 66.40  ? 605 ILE C O   1 
ATOM   13730 C CB  . ILE C 1 605 ? 131.266 140.056 157.043 1.00 58.94  ? 605 ILE C CB  1 
ATOM   13731 C CG1 . ILE C 1 605 ? 130.743 139.985 158.485 1.00 61.60  ? 605 ILE C CG1 1 
ATOM   13732 C CG2 . ILE C 1 605 ? 130.999 141.433 156.429 1.00 59.44  ? 605 ILE C CG2 1 
ATOM   13733 C CD1 . ILE C 1 605 ? 131.551 140.801 159.486 1.00 56.83  ? 605 ILE C CD1 1 
ATOM   13734 N N   . GLY C 1 606 ? 130.014 136.645 156.730 1.00 59.82  ? 606 GLY C N   1 
ATOM   13735 C CA  . GLY C 1 606 ? 130.137 135.276 157.226 1.00 56.98  ? 606 GLY C CA  1 
ATOM   13736 C C   . GLY C 1 606 ? 130.046 135.101 158.746 1.00 69.22  ? 606 GLY C C   1 
ATOM   13737 O O   . GLY C 1 606 ? 130.381 134.025 159.228 1.00 75.55  ? 606 GLY C O   1 
ATOM   13738 N N   . MET C 1 607 ? 129.595 136.112 159.507 1.00 67.07  ? 607 MET C N   1 
ATOM   13739 C CA  . MET C 1 607 ? 129.532 136.113 160.983 1.00 64.06  ? 607 MET C CA  1 
ATOM   13740 C C   . MET C 1 607 ? 128.094 136.081 161.521 1.00 62.34  ? 607 MET C C   1 
ATOM   13741 O O   . MET C 1 607 ? 127.747 136.806 162.443 1.00 67.09  ? 607 MET C O   1 
ATOM   13742 C CB  . MET C 1 607 ? 130.359 137.278 161.556 1.00 64.06  ? 607 MET C CB  1 
ATOM   13743 C CG  . MET C 1 607 ? 131.867 137.081 161.378 1.00 61.75  ? 607 MET C CG  1 
ATOM   13744 S SD  . MET C 1 607 ? 132.642 135.884 162.496 1.00 63.01  ? 607 MET C SD  1 
ATOM   13745 C CE  . MET C 1 607 ? 132.735 136.807 164.043 1.00 60.99  ? 607 MET C CE  1 
ATOM   13746 N N   . GLY C 1 608 ? 127.213 135.296 160.898 1.00 67.37  ? 608 GLY C N   1 
ATOM   13747 C CA  . GLY C 1 608 ? 125.757 135.409 161.028 1.00 67.92  ? 608 GLY C CA  1 
ATOM   13748 C C   . GLY C 1 608 ? 125.123 135.266 162.422 1.00 74.14  ? 608 GLY C C   1 
ATOM   13749 O O   . GLY C 1 608 ? 124.136 135.933 162.694 1.00 85.52  ? 608 GLY C O   1 
ATOM   13750 N N   . GLU C 1 609 ? 125.639 134.418 163.314 1.00 87.10  ? 609 GLU C N   1 
ATOM   13751 C CA  . GLU C 1 609 ? 125.038 134.182 164.650 1.00 91.22  ? 609 GLU C CA  1 
ATOM   13752 C C   . GLU C 1 609 ? 123.559 133.717 164.584 1.00 89.62  ? 609 GLU C C   1 
ATOM   13753 O O   . GLU C 1 609 ? 122.700 134.141 165.355 1.00 88.49  ? 609 GLU C O   1 
ATOM   13754 C CB  . GLU C 1 609 ? 125.279 135.368 165.620 1.00 91.12  ? 609 GLU C CB  1 
ATOM   13755 C CG  . GLU C 1 609 ? 126.769 135.697 165.820 1.00 95.08  ? 609 GLU C CG  1 
ATOM   13756 C CD  . GLU C 1 609 ? 126.990 136.915 166.733 1.00 97.36  ? 609 GLU C CD  1 
ATOM   13757 O OE1 . GLU C 1 609 ? 126.636 136.834 167.931 1.00 93.83  ? 609 GLU C OE1 1 
ATOM   13758 O OE2 . GLU C 1 609 ? 127.579 137.928 166.281 1.00 98.11  ? 609 GLU C OE2 1 
ATOM   13759 N N   . LEU C 1 610 ? 123.258 132.822 163.639 1.00 81.33  ? 610 LEU C N   1 
ATOM   13760 C CA  . LEU C 1 610 ? 121.944 132.219 163.390 1.00 77.94  ? 610 LEU C CA  1 
ATOM   13761 C C   . LEU C 1 610 ? 121.560 131.181 164.464 1.00 80.86  ? 610 LEU C C   1 
ATOM   13762 O O   . LEU C 1 610 ? 122.201 130.139 164.566 1.00 84.45  ? 610 LEU C O   1 
ATOM   13763 C CB  . LEU C 1 610 ? 122.039 131.585 161.991 1.00 80.88  ? 610 LEU C CB  1 
ATOM   13764 C CG  . LEU C 1 610 ? 120.793 130.873 161.469 1.00 81.44  ? 610 LEU C CG  1 
ATOM   13765 C CD1 . LEU C 1 610 ? 119.608 131.807 161.282 1.00 83.52  ? 610 LEU C CD1 1 
ATOM   13766 C CD2 . LEU C 1 610 ? 121.110 130.285 160.105 1.00 81.25  ? 610 LEU C CD2 1 
ATOM   13767 N N   . ALA C 1 611 ? 120.519 131.429 165.260 1.00 99.90  ? 611 ALA C N   1 
ATOM   13768 C CA  . ALA C 1 611 ? 120.170 130.585 166.408 1.00 99.36  ? 611 ALA C CA  1 
ATOM   13769 C C   . ALA C 1 611 ? 118.675 130.609 166.768 1.00 101.47 ? 611 ALA C C   1 
ATOM   13770 O O   . ALA C 1 611 ? 117.973 131.587 166.517 1.00 103.85 ? 611 ALA C O   1 
ATOM   13771 C CB  . ALA C 1 611 ? 121.006 131.036 167.612 1.00 96.19  ? 611 ALA C CB  1 
ATOM   13772 N N   . PHE C 1 612 ? 118.202 129.547 167.422 1.00 106.52 ? 612 PHE C N   1 
ATOM   13773 C CA  . PHE C 1 612 ? 116.868 129.453 168.017 1.00 105.40 ? 612 PHE C CA  1 
ATOM   13774 C C   . PHE C 1 612 ? 116.874 130.088 169.420 1.00 106.94 ? 612 PHE C C   1 
ATOM   13775 O O   . PHE C 1 612 ? 117.155 129.418 170.412 1.00 108.04 ? 612 PHE C O   1 
ATOM   13776 C CB  . PHE C 1 612 ? 116.467 127.969 168.018 1.00 105.42 ? 612 PHE C CB  1 
ATOM   13777 C CG  . PHE C 1 612 ? 115.049 127.663 168.447 1.00 108.01 ? 612 PHE C CG  1 
ATOM   13778 C CD1 . PHE C 1 612 ? 113.983 127.879 167.559 1.00 106.04 ? 612 PHE C CD1 1 
ATOM   13779 C CD2 . PHE C 1 612 ? 114.796 127.083 169.704 1.00 106.98 ? 612 PHE C CD2 1 
ATOM   13780 C CE1 . PHE C 1 612 ? 112.679 127.504 167.911 1.00 106.21 ? 612 PHE C CE1 1 
ATOM   13781 C CE2 . PHE C 1 612 ? 113.491 126.698 170.054 1.00 105.99 ? 612 PHE C CE2 1 
ATOM   13782 C CZ  . PHE C 1 612 ? 112.431 126.907 169.159 1.00 106.30 ? 612 PHE C CZ  1 
ATOM   13783 N N   . GLN C 1 613 ? 116.629 131.400 169.500 1.00 111.68 ? 613 GLN C N   1 
ATOM   13784 C CA  . GLN C 1 613 ? 116.765 132.200 170.727 1.00 113.07 ? 613 GLN C CA  1 
ATOM   13785 C C   . GLN C 1 613 ? 115.825 131.707 171.841 1.00 112.93 ? 613 GLN C C   1 
ATOM   13786 O O   . GLN C 1 613 ? 114.609 131.753 171.686 1.00 112.90 ? 613 GLN C O   1 
ATOM   13787 C CB  . GLN C 1 613 ? 116.447 133.675 170.409 1.00 109.90 ? 613 GLN C CB  1 
ATOM   13788 C CG  . GLN C 1 613 ? 117.351 134.347 169.362 1.00 111.97 ? 613 GLN C CG  1 
ATOM   13789 C CD  . GLN C 1 613 ? 118.786 134.592 169.820 1.00 115.79 ? 613 GLN C CD  1 
ATOM   13790 O OE1 . GLN C 1 613 ? 119.160 134.408 170.968 1.00 115.54 ? 613 GLN C OE1 1 
ATOM   13791 N NE2 . GLN C 1 613 ? 119.654 135.025 168.937 1.00 110.67 ? 613 GLN C NE2 1 
ATOM   13792 N N   . GLU C 1 614 ? 116.330 131.235 172.981 1.00 118.01 ? 614 GLU C N   1 
ATOM   13793 C CA  . GLU C 1 614 ? 115.481 130.539 173.961 1.00 118.38 ? 614 GLU C CA  1 
ATOM   13794 C C   . GLU C 1 614 ? 114.469 131.450 174.687 1.00 121.37 ? 614 GLU C C   1 
ATOM   13795 O O   . GLU C 1 614 ? 113.374 130.996 175.017 1.00 120.85 ? 614 GLU C O   1 
ATOM   13796 C CB  . GLU C 1 614 ? 116.339 129.807 175.005 1.00 117.04 ? 614 GLU C CB  1 
ATOM   13797 N N   . GLN C 1 615 ? 114.815 132.713 174.951 1.00 118.27 ? 615 GLN C N   1 
ATOM   13798 C CA  . GLN C 1 615 ? 114.046 133.616 175.815 1.00 115.14 ? 615 GLN C CA  1 
ATOM   13799 C C   . GLN C 1 615 ? 112.917 134.385 175.110 1.00 116.41 ? 615 GLN C C   1 
ATOM   13800 O O   . GLN C 1 615 ? 112.027 134.907 175.781 1.00 118.78 ? 615 GLN C O   1 
ATOM   13801 C CB  . GLN C 1 615 ? 115.005 134.571 176.557 1.00 112.47 ? 615 GLN C CB  1 
ATOM   13802 C CG  . GLN C 1 615 ? 115.439 135.865 175.838 1.00 113.92 ? 615 GLN C CG  1 
ATOM   13803 C CD  . GLN C 1 615 ? 116.420 135.690 174.680 1.00 117.31 ? 615 GLN C CD  1 
ATOM   13804 O OE1 . GLN C 1 615 ? 116.741 134.596 174.243 1.00 117.97 ? 615 GLN C OE1 1 
ATOM   13805 N NE2 . GLN C 1 615 ? 116.937 136.767 174.137 1.00 115.18 ? 615 GLN C NE2 1 
ATOM   13806 N N   . LEU C 1 616 ? 112.951 134.496 173.777 1.00 106.51 ? 616 LEU C N   1 
ATOM   13807 C CA  . LEU C 1 616 ? 111.953 135.237 172.998 1.00 106.35 ? 616 LEU C CA  1 
ATOM   13808 C C   . LEU C 1 616 ? 110.629 134.464 172.913 1.00 106.12 ? 616 LEU C C   1 
ATOM   13809 O O   . LEU C 1 616 ? 110.632 133.248 172.736 1.00 107.10 ? 616 LEU C O   1 
ATOM   13810 C CB  . LEU C 1 616 ? 112.493 135.552 171.586 1.00 104.60 ? 616 LEU C CB  1 
ATOM   13811 C CG  . LEU C 1 616 ? 113.782 136.389 171.534 1.00 104.31 ? 616 LEU C CG  1 
ATOM   13812 C CD1 . LEU C 1 616 ? 114.147 136.676 170.081 1.00 101.63 ? 616 LEU C CD1 1 
ATOM   13813 C CD2 . LEU C 1 616 ? 113.633 137.726 172.254 1.00 104.26 ? 616 LEU C CD2 1 
ATOM   13814 N N   . ARG C 1 617 ? 109.479 135.149 172.972 1.00 95.70  ? 617 ARG C N   1 
ATOM   13815 C CA  . ARG C 1 617 ? 108.149 134.467 172.915 1.00 95.42  ? 617 ARG C CA  1 
ATOM   13816 C C   . ARG C 1 617 ? 107.921 133.880 171.530 1.00 97.10  ? 617 ARG C C   1 
ATOM   13817 O O   . ARG C 1 617 ? 107.438 132.746 171.456 1.00 91.06  ? 617 ARG C O   1 
ATOM   13818 C CB  . ARG C 1 617 ? 107.035 135.467 173.223 1.00 90.97  ? 617 ARG C CB  1 
ATOM   13819 C CG  . ARG C 1 617 ? 105.654 134.862 173.420 1.00 90.08  ? 617 ARG C CG  1 
ATOM   13820 C CD  . ARG C 1 617 ? 104.659 136.002 173.508 1.00 95.52  ? 617 ARG C CD  1 
ATOM   13821 N NE  . ARG C 1 617 ? 103.422 135.726 174.224 1.00 98.54  ? 617 ARG C NE  1 
ATOM   13822 C CZ  . ARG C 1 617 ? 102.307 135.268 173.668 1.00 98.75  ? 617 ARG C CZ  1 
ATOM   13823 N NH1 . ARG C 1 617 ? 101.235 135.061 174.412 1.00 96.79  ? 617 ARG C NH1 1 
ATOM   13824 N NH2 . ARG C 1 617 ? 102.265 135.009 172.375 1.00 98.63  ? 617 ARG C NH2 1 
ATOM   13825 N N   . PHE C 1 618 ? 108.250 134.630 170.482 1.00 96.62  ? 618 PHE C N   1 
ATOM   13826 C CA  . PHE C 1 618 ? 108.087 134.258 169.074 1.00 90.72  ? 618 PHE C CA  1 
ATOM   13827 C C   . PHE C 1 618 ? 109.380 133.698 168.456 1.00 92.95  ? 618 PHE C C   1 
ATOM   13828 O O   . PHE C 1 618 ? 109.658 133.926 167.282 1.00 95.13  ? 618 PHE C O   1 
ATOM   13829 C CB  . PHE C 1 618 ? 107.532 135.464 168.303 1.00 89.94  ? 618 PHE C CB  1 
ATOM   13830 C CG  . PHE C 1 618 ? 106.221 135.999 168.841 1.00 89.91  ? 618 PHE C CG  1 
ATOM   13831 C CD1 . PHE C 1 618 ? 105.039 135.256 168.686 1.00 86.79  ? 618 PHE C CD1 1 
ATOM   13832 C CD2 . PHE C 1 618 ? 106.185 137.229 169.515 1.00 89.34  ? 618 PHE C CD2 1 
ATOM   13833 C CE1 . PHE C 1 618 ? 103.832 135.731 169.222 1.00 84.37  ? 618 PHE C CE1 1 
ATOM   13834 C CE2 . PHE C 1 618 ? 104.980 137.701 170.054 1.00 90.64  ? 618 PHE C CE2 1 
ATOM   13835 C CZ  . PHE C 1 618 ? 103.803 136.956 169.907 1.00 88.47  ? 618 PHE C CZ  1 
ATOM   13836 N N   . ARG C 1 619 ? 110.220 133.012 169.233 1.00 102.49 ? 619 ARG C N   1 
ATOM   13837 C CA  . ARG C 1 619 ? 111.567 132.546 168.774 1.00 97.93  ? 619 ARG C CA  1 
ATOM   13838 C C   . ARG C 1 619 ? 111.563 131.702 167.494 1.00 96.19  ? 619 ARG C C   1 
ATOM   13839 O O   . ARG C 1 619 ? 112.573 131.743 166.797 1.00 97.02  ? 619 ARG C O   1 
ATOM   13840 C CB  . ARG C 1 619 ? 112.231 131.763 169.907 1.00 102.06 ? 619 ARG C CB  1 
ATOM   13841 C CG  . ARG C 1 619 ? 111.526 130.467 170.275 1.00 100.28 ? 619 ARG C CG  1 
ATOM   13842 C CD  . ARG C 1 619 ? 112.043 129.925 171.589 1.00 100.09 ? 619 ARG C CD  1 
ATOM   13843 N NE  . ARG C 1 619 ? 111.250 128.792 172.037 1.00 103.79 ? 619 ARG C NE  1 
ATOM   13844 C CZ  . ARG C 1 619 ? 111.393 128.198 173.214 1.00 102.50 ? 619 ARG C CZ  1 
ATOM   13845 N NH1 . ARG C 1 619 ? 110.626 127.169 173.531 1.00 98.34  ? 619 ARG C NH1 1 
ATOM   13846 N NH2 . ARG C 1 619 ? 112.297 128.636 174.070 1.00 100.97 ? 619 ARG C NH2 1 
ATOM   13847 N N   . GLY C 1 620 ? 110.551 130.888 167.241 1.00 83.47  ? 620 GLY C N   1 
ATOM   13848 C CA  . GLY C 1 620 ? 110.441 130.165 165.973 1.00 87.03  ? 620 GLY C CA  1 
ATOM   13849 C C   . GLY C 1 620 ? 110.167 131.082 164.781 1.00 87.54  ? 620 GLY C C   1 
ATOM   13850 O O   . GLY C 1 620 ? 110.713 130.877 163.703 1.00 84.70  ? 620 GLY C O   1 
ATOM   13851 N N   . VAL C 1 621 ? 109.378 132.140 164.968 1.00 88.88  ? 621 VAL C N   1 
ATOM   13852 C CA  . VAL C 1 621 ? 109.086 133.122 163.914 1.00 86.75  ? 621 VAL C CA  1 
ATOM   13853 C C   . VAL C 1 621 ? 110.284 134.041 163.679 1.00 83.70  ? 621 VAL C C   1 
ATOM   13854 O O   . VAL C 1 621 ? 110.602 134.340 162.537 1.00 86.47  ? 621 VAL C O   1 
ATOM   13855 C CB  . VAL C 1 621 ? 107.817 133.936 164.216 1.00 85.17  ? 621 VAL C CB  1 
ATOM   13856 C CG1 . VAL C 1 621 ? 107.419 134.759 162.989 1.00 84.69  ? 621 VAL C CG1 1 
ATOM   13857 C CG2 . VAL C 1 621 ? 106.619 133.053 164.575 1.00 87.41  ? 621 VAL C CG2 1 
ATOM   13858 N N   . VAL C 1 622 ? 111.007 134.429 164.731 1.00 79.29  ? 622 VAL C N   1 
ATOM   13859 C CA  . VAL C 1 622 ? 112.286 135.150 164.620 1.00 77.91  ? 622 VAL C CA  1 
ATOM   13860 C C   . VAL C 1 622 ? 113.318 134.320 163.847 1.00 81.86  ? 622 VAL C C   1 
ATOM   13861 O O   . VAL C 1 622 ? 113.934 134.845 162.928 1.00 86.44  ? 622 VAL C O   1 
ATOM   13862 C CB  . VAL C 1 622 ? 112.793 135.578 166.010 1.00 77.61  ? 622 VAL C CB  1 
ATOM   13863 C CG1 . VAL C 1 622 ? 114.204 136.142 166.004 1.00 74.93  ? 622 VAL C CG1 1 
ATOM   13864 C CG2 . VAL C 1 622 ? 111.887 136.657 166.597 1.00 82.01  ? 622 VAL C CG2 1 
ATOM   13865 N N   . LEU C 1 623 ? 113.464 133.016 164.118 1.00 82.46  ? 623 LEU C N   1 
ATOM   13866 C CA  . LEU C 1 623 ? 114.324 132.131 163.324 1.00 77.19  ? 623 LEU C CA  1 
ATOM   13867 C C   . LEU C 1 623 ? 113.853 131.995 161.863 1.00 81.14  ? 623 LEU C C   1 
ATOM   13868 O O   . LEU C 1 623 ? 114.674 132.074 160.953 1.00 83.16  ? 623 LEU C O   1 
ATOM   13869 C CB  . LEU C 1 623 ? 114.440 130.766 164.022 1.00 80.30  ? 623 LEU C CB  1 
ATOM   13870 C CG  . LEU C 1 623 ? 115.280 129.732 163.253 1.00 84.94  ? 623 LEU C CG  1 
ATOM   13871 C CD1 . LEU C 1 623 ? 116.728 130.171 163.086 1.00 85.90  ? 623 LEU C CD1 1 
ATOM   13872 C CD2 . LEU C 1 623 ? 115.273 128.391 163.974 1.00 84.90  ? 623 LEU C CD2 1 
ATOM   13873 N N   . LEU C 1 624 ? 112.556 131.847 161.596 1.00 82.30  ? 624 LEU C N   1 
ATOM   13874 C CA  . LEU C 1 624 ? 112.033 131.859 160.227 1.00 80.87  ? 624 LEU C CA  1 
ATOM   13875 C C   . LEU C 1 624 ? 112.273 133.197 159.508 1.00 85.10  ? 624 LEU C C   1 
ATOM   13876 O O   . LEU C 1 624 ? 112.571 133.175 158.319 1.00 89.23  ? 624 LEU C O   1 
ATOM   13877 C CB  . LEU C 1 624 ? 110.541 131.500 160.231 1.00 82.26  ? 624 LEU C CB  1 
ATOM   13878 C CG  . LEU C 1 624 ? 110.261 130.018 160.522 1.00 84.71  ? 624 LEU C CG  1 
ATOM   13879 C CD1 . LEU C 1 624 ? 108.786 129.821 160.857 1.00 83.82  ? 624 LEU C CD1 1 
ATOM   13880 C CD2 . LEU C 1 624 ? 110.594 129.139 159.320 1.00 82.11  ? 624 LEU C CD2 1 
ATOM   13881 N N   . LEU C 1 625 ? 112.210 134.349 160.188 1.00 74.77  ? 625 LEU C N   1 
ATOM   13882 C CA  . LEU C 1 625 ? 112.590 135.640 159.609 1.00 69.72  ? 625 LEU C CA  1 
ATOM   13883 C C   . LEU C 1 625 ? 114.077 135.705 159.258 1.00 79.57  ? 625 LEU C C   1 
ATOM   13884 O O   . LEU C 1 625 ? 114.417 136.227 158.203 1.00 89.46  ? 625 LEU C O   1 
ATOM   13885 C CB  . LEU C 1 625 ? 112.236 136.791 160.558 1.00 72.98  ? 625 LEU C CB  1 
ATOM   13886 C CG  . LEU C 1 625 ? 110.764 137.215 160.566 1.00 82.33  ? 625 LEU C CG  1 
ATOM   13887 C CD1 . LEU C 1 625 ? 110.558 138.319 161.587 1.00 77.69  ? 625 LEU C CD1 1 
ATOM   13888 C CD2 . LEU C 1 625 ? 110.324 137.764 159.217 1.00 79.18  ? 625 LEU C CD2 1 
ATOM   13889 N N   . LEU C 1 626 ? 114.971 135.154 160.083 1.00 74.79  ? 626 LEU C N   1 
ATOM   13890 C CA  . LEU C 1 626 ? 116.391 135.054 159.729 1.00 66.02  ? 626 LEU C CA  1 
ATOM   13891 C C   . LEU C 1 626 ? 116.618 134.109 158.552 1.00 68.15  ? 626 LEU C C   1 
ATOM   13892 O O   . LEU C 1 626 ? 117.353 134.456 157.639 1.00 70.25  ? 626 LEU C O   1 
ATOM   13893 C CB  . LEU C 1 626 ? 117.227 134.585 160.922 1.00 66.93  ? 626 LEU C CB  1 
ATOM   13894 C CG  . LEU C 1 626 ? 117.254 135.543 162.112 1.00 71.44  ? 626 LEU C CG  1 
ATOM   13895 C CD1 . LEU C 1 626 ? 117.961 134.860 163.275 1.00 68.35  ? 626 LEU C CD1 1 
ATOM   13896 C CD2 . LEU C 1 626 ? 117.986 136.835 161.771 1.00 67.91  ? 626 LEU C CD2 1 
ATOM   13897 N N   . LEU C 1 627 ? 115.980 132.939 158.520 1.00 71.49  ? 627 LEU C N   1 
ATOM   13898 C CA  . LEU C 1 627 ? 116.094 132.001 157.399 1.00 69.99  ? 627 LEU C CA  1 
ATOM   13899 C C   . LEU C 1 627 ? 115.517 132.578 156.103 1.00 71.65  ? 627 LEU C C   1 
ATOM   13900 O O   . LEU C 1 627 ? 116.102 132.392 155.044 1.00 73.92  ? 627 LEU C O   1 
ATOM   13901 C CB  . LEU C 1 627 ? 115.417 130.670 157.760 1.00 70.80  ? 627 LEU C CB  1 
ATOM   13902 C CG  . LEU C 1 627 ? 116.151 129.865 158.844 1.00 69.43  ? 627 LEU C CG  1 
ATOM   13903 C CD1 . LEU C 1 627 ? 115.289 128.683 159.264 1.00 69.66  ? 627 LEU C CD1 1 
ATOM   13904 C CD2 . LEU C 1 627 ? 117.486 129.329 158.345 1.00 72.81  ? 627 LEU C CD2 1 
ATOM   13905 N N   . ALA C 1 628 ? 114.422 133.335 156.167 1.00 74.27  ? 628 ALA C N   1 
ATOM   13906 C CA  . ALA C 1 628 ? 113.928 134.117 155.041 1.00 66.60  ? 628 ALA C CA  1 
ATOM   13907 C C   . ALA C 1 628 ? 114.939 135.176 154.593 1.00 70.31  ? 628 ALA C C   1 
ATOM   13908 O O   . ALA C 1 628 ? 115.271 135.211 153.413 1.00 76.15  ? 628 ALA C O   1 
ATOM   13909 C CB  . ALA C 1 628 ? 112.589 134.741 155.425 1.00 61.38  ? 628 ALA C CB  1 
ATOM   13910 N N   . TYR C 1 629 ? 115.512 135.983 155.492 1.00 58.50  ? 629 TYR C N   1 
ATOM   13911 C CA  . TYR C 1 629 ? 116.533 136.970 155.119 1.00 56.25  ? 629 TYR C CA  1 
ATOM   13912 C C   . TYR C 1 629 ? 117.769 136.323 154.492 1.00 62.59  ? 629 TYR C C   1 
ATOM   13913 O O   . TYR C 1 629 ? 118.222 136.784 153.446 1.00 73.34  ? 629 TYR C O   1 
ATOM   13914 C CB  . TYR C 1 629 ? 116.920 137.835 156.325 1.00 58.50  ? 629 TYR C CB  1 
ATOM   13915 C CG  . TYR C 1 629 ? 118.147 138.705 156.103 1.00 58.38  ? 629 TYR C CG  1 
ATOM   13916 C CD1 . TYR C 1 629 ? 118.056 139.944 155.434 1.00 54.72  ? 629 TYR C CD1 1 
ATOM   13917 C CD2 . TYR C 1 629 ? 119.397 138.244 156.541 1.00 60.10  ? 629 TYR C CD2 1 
ATOM   13918 C CE1 . TYR C 1 629 ? 119.216 140.706 155.190 1.00 56.62  ? 629 TYR C CE1 1 
ATOM   13919 C CE2 . TYR C 1 629 ? 120.550 139.006 156.306 1.00 67.78  ? 629 TYR C CE2 1 
ATOM   13920 C CZ  . TYR C 1 629 ? 120.476 140.234 155.622 1.00 69.10  ? 629 TYR C CZ  1 
ATOM   13921 O OH  . TYR C 1 629 ? 121.618 140.953 155.424 1.00 58.80  ? 629 TYR C OH  1 
ATOM   13922 N N   . VAL C 1 630 ? 118.307 135.250 155.074 1.00 63.56  ? 630 VAL C N   1 
ATOM   13923 C CA  . VAL C 1 630 ? 119.490 134.536 154.559 1.00 64.99  ? 630 VAL C CA  1 
ATOM   13924 C C   . VAL C 1 630 ? 119.243 134.014 153.157 1.00 62.84  ? 630 VAL C C   1 
ATOM   13925 O O   . VAL C 1 630 ? 120.018 134.294 152.251 1.00 66.65  ? 630 VAL C O   1 
ATOM   13926 C CB  . VAL C 1 630 ? 119.880 133.382 155.500 1.00 64.10  ? 630 VAL C CB  1 
ATOM   13927 C CG1 . VAL C 1 630 ? 120.896 132.411 154.894 1.00 61.26  ? 630 VAL C CG1 1 
ATOM   13928 C CG2 . VAL C 1 630 ? 120.518 133.934 156.768 1.00 63.37  ? 630 VAL C CG2 1 
ATOM   13929 N N   . LEU C 1 631 ? 118.150 133.279 152.940 1.00 66.46  ? 631 LEU C N   1 
ATOM   13930 C CA  . LEU C 1 631 ? 117.852 132.701 151.641 1.00 65.30  ? 631 LEU C CA  1 
ATOM   13931 C C   . LEU C 1 631 ? 117.612 133.786 150.596 1.00 66.00  ? 631 LEU C C   1 
ATOM   13932 O O   . LEU C 1 631 ? 118.235 133.745 149.542 1.00 70.06  ? 631 LEU C O   1 
ATOM   13933 C CB  . LEU C 1 631 ? 116.676 131.722 151.781 1.00 65.07  ? 631 LEU C CB  1 
ATOM   13934 C CG  . LEU C 1 631 ? 117.023 130.463 152.599 1.00 67.40  ? 631 LEU C CG  1 
ATOM   13935 C CD1 . LEU C 1 631 ? 115.763 129.651 152.862 1.00 69.73  ? 631 LEU C CD1 1 
ATOM   13936 C CD2 . LEU C 1 631 ? 118.005 129.555 151.872 1.00 65.19  ? 631 LEU C CD2 1 
ATOM   13937 N N   . LEU C 1 632 ? 116.807 134.812 150.886 1.00 67.20  ? 632 LEU C N   1 
ATOM   13938 C CA  . LEU C 1 632 ? 116.588 135.917 149.954 1.00 60.01  ? 632 LEU C CA  1 
ATOM   13939 C C   . LEU C 1 632 ? 117.867 136.691 149.641 1.00 58.09  ? 632 LEU C C   1 
ATOM   13940 O O   . LEU C 1 632 ? 118.115 137.018 148.486 1.00 68.09  ? 632 LEU C O   1 
ATOM   13941 C CB  . LEU C 1 632 ? 115.527 136.869 150.516 1.00 60.36  ? 632 LEU C CB  1 
ATOM   13942 C CG  . LEU C 1 632 ? 114.108 136.286 150.567 1.00 64.17  ? 632 LEU C CG  1 
ATOM   13943 C CD1 . LEU C 1 632 ? 113.175 137.344 151.144 1.00 65.19  ? 632 LEU C CD1 1 
ATOM   13944 C CD2 . LEU C 1 632 ? 113.588 135.900 149.188 1.00 64.52  ? 632 LEU C CD2 1 
ATOM   13945 N N   . THR C 1 633 ? 118.705 136.960 150.633 1.00 59.95  ? 633 THR C N   1 
ATOM   13946 C CA  . THR C 1 633 ? 119.979 137.670 150.463 1.00 62.05  ? 633 THR C CA  1 
ATOM   13947 C C   . THR C 1 633 ? 121.001 136.854 149.686 1.00 63.65  ? 633 THR C C   1 
ATOM   13948 O O   . THR C 1 633 ? 121.725 137.411 148.876 1.00 62.93  ? 633 THR C O   1 
ATOM   13949 C CB  . THR C 1 633 ? 120.561 138.046 151.825 1.00 57.87  ? 633 THR C CB  1 
ATOM   13950 O OG1 . THR C 1 633 ? 119.654 138.898 152.460 1.00 66.25  ? 633 THR C OG1 1 
ATOM   13951 C CG2 . THR C 1 633 ? 121.896 138.772 151.757 1.00 62.48  ? 633 THR C CG2 1 
ATOM   13952 N N   . TYR C 1 634 ? 121.087 135.541 149.883 1.00 73.12  ? 634 TYR C N   1 
ATOM   13953 C CA  . TYR C 1 634 ? 122.061 134.720 149.168 1.00 59.43  ? 634 TYR C CA  1 
ATOM   13954 C C   . TYR C 1 634 ? 121.596 134.444 147.733 1.00 65.11  ? 634 TYR C C   1 
ATOM   13955 O O   . TYR C 1 634 ? 122.421 134.449 146.830 1.00 71.64  ? 634 TYR C O   1 
ATOM   13956 C CB  . TYR C 1 634 ? 122.382 133.451 149.971 1.00 65.97  ? 634 TYR C CB  1 
ATOM   13957 C CG  . TYR C 1 634 ? 123.295 133.629 151.188 1.00 83.64  ? 634 TYR C CG  1 
ATOM   13958 C CD1 . TYR C 1 634 ? 123.408 134.853 151.881 1.00 81.25  ? 634 TYR C CD1 1 
ATOM   13959 C CD2 . TYR C 1 634 ? 124.069 132.539 151.624 1.00 73.69  ? 634 TYR C CD2 1 
ATOM   13960 C CE1 . TYR C 1 634 ? 124.271 134.992 152.977 1.00 73.79  ? 634 TYR C CE1 1 
ATOM   13961 C CE2 . TYR C 1 634 ? 124.940 132.677 152.717 1.00 71.23  ? 634 TYR C CE2 1 
ATOM   13962 C CZ  . TYR C 1 634 ? 125.047 133.908 153.400 1.00 74.15  ? 634 TYR C CZ  1 
ATOM   13963 O OH  . TYR C 1 634 ? 125.901 134.041 154.451 1.00 78.69  ? 634 TYR C OH  1 
ATOM   13964 N N   . VAL C 1 635 ? 120.290 134.339 147.468 1.00 68.64  ? 635 VAL C N   1 
ATOM   13965 C CA  . VAL C 1 635 ? 119.721 134.406 146.112 1.00 59.30  ? 635 VAL C CA  1 
ATOM   13966 C C   . VAL C 1 635 ? 120.022 135.754 145.446 1.00 59.44  ? 635 VAL C C   1 
ATOM   13967 O O   . VAL C 1 635 ? 120.440 135.781 144.295 1.00 68.21  ? 635 VAL C O   1 
ATOM   13968 C CB  . VAL C 1 635 ? 118.206 134.138 146.144 1.00 58.68  ? 635 VAL C CB  1 
ATOM   13969 C CG1 . VAL C 1 635 ? 117.521 134.345 144.795 1.00 67.70  ? 635 VAL C CG1 1 
ATOM   13970 C CG2 . VAL C 1 635 ? 117.923 132.693 146.541 1.00 58.60  ? 635 VAL C CG2 1 
ATOM   13971 N N   . LEU C 1 636 ? 119.877 136.879 146.152 1.00 52.16  ? 636 LEU C N   1 
ATOM   13972 C CA  . LEU C 1 636 ? 120.240 138.202 145.643 1.00 53.13  ? 636 LEU C CA  1 
ATOM   13973 C C   . LEU C 1 636 ? 121.741 138.321 145.342 1.00 60.50  ? 636 LEU C C   1 
ATOM   13974 O O   . LEU C 1 636 ? 122.089 138.800 144.268 1.00 71.99  ? 636 LEU C O   1 
ATOM   13975 C CB  . LEU C 1 636 ? 119.759 139.270 146.635 1.00 64.45  ? 636 LEU C CB  1 
ATOM   13976 C CG  . LEU C 1 636 ? 120.214 140.701 146.319 1.00 69.83  ? 636 LEU C CG  1 
ATOM   13977 C CD1 . LEU C 1 636 ? 119.577 141.231 145.040 1.00 61.35  ? 636 LEU C CD1 1 
ATOM   13978 C CD2 . LEU C 1 636 ? 119.866 141.620 147.482 1.00 62.85  ? 636 LEU C CD2 1 
ATOM   13979 N N   . LEU C 1 637 ? 122.639 137.890 146.222 1.00 62.63  ? 637 LEU C N   1 
ATOM   13980 C CA  . LEU C 1 637 ? 124.085 137.921 145.968 1.00 58.81  ? 637 LEU C CA  1 
ATOM   13981 C C   . LEU C 1 637 ? 124.471 137.015 144.795 1.00 58.59  ? 637 LEU C C   1 
ATOM   13982 O O   . LEU C 1 637 ? 125.312 137.385 143.995 1.00 63.27  ? 637 LEU C O   1 
ATOM   13983 C CB  . LEU C 1 637 ? 124.860 137.532 147.235 1.00 65.31  ? 637 LEU C CB  1 
ATOM   13984 C CG  . LEU C 1 637 ? 124.816 138.567 148.371 1.00 68.45  ? 637 LEU C CG  1 
ATOM   13985 C CD1 . LEU C 1 637 ? 125.430 137.978 149.637 1.00 65.09  ? 637 LEU C CD1 1 
ATOM   13986 C CD2 . LEU C 1 637 ? 125.588 139.834 148.024 1.00 65.47  ? 637 LEU C CD2 1 
ATOM   13987 N N   . LEU C 1 638 ? 123.829 135.858 144.643 1.00 67.72  ? 638 LEU C N   1 
ATOM   13988 C CA  . LEU C 1 638 ? 124.001 134.946 143.517 1.00 61.59  ? 638 LEU C CA  1 
ATOM   13989 C C   . LEU C 1 638 ? 123.518 135.564 142.192 1.00 62.02  ? 638 LEU C C   1 
ATOM   13990 O O   . LEU C 1 638 ? 124.254 135.548 141.213 1.00 63.36  ? 638 LEU C O   1 
ATOM   13991 C CB  . LEU C 1 638 ? 123.274 133.651 143.906 1.00 62.84  ? 638 LEU C CB  1 
ATOM   13992 C CG  . LEU C 1 638 ? 123.366 132.457 142.958 1.00 65.56  ? 638 LEU C CG  1 
ATOM   13993 C CD1 . LEU C 1 638 ? 124.804 131.990 142.775 1.00 62.24  ? 638 LEU C CD1 1 
ATOM   13994 C CD2 . LEU C 1 638 ? 122.552 131.325 143.577 1.00 64.21  ? 638 LEU C CD2 1 
ATOM   13995 N N   . ASN C 1 639 ? 122.349 136.211 142.173 1.00 73.09  ? 639 ASN C N   1 
ATOM   13996 C CA  . ASN C 1 639 ? 121.879 137.027 141.049 1.00 63.16  ? 639 ASN C CA  1 
ATOM   13997 C C   . ASN C 1 639 ? 122.844 138.176 140.726 1.00 64.07  ? 639 ASN C C   1 
ATOM   13998 O O   . ASN C 1 639 ? 123.111 138.436 139.559 1.00 75.44  ? 639 ASN C O   1 
ATOM   13999 C CB  . ASN C 1 639 ? 120.496 137.632 141.350 1.00 57.18  ? 639 ASN C CB  1 
ATOM   14000 C CG  . ASN C 1 639 ? 119.324 136.673 141.419 1.00 66.19  ? 639 ASN C CG  1 
ATOM   14001 O OD1 . ASN C 1 639 ? 119.381 135.528 141.022 1.00 68.69  ? 639 ASN C OD1 1 
ATOM   14002 N ND2 . ASN C 1 639 ? 118.199 137.119 141.922 1.00 68.68  ? 639 ASN C ND2 1 
ATOM   14003 N N   . MET C 1 640 ? 123.375 138.870 141.733 1.00 59.81  ? 640 MET C N   1 
ATOM   14004 C CA  . MET C 1 640 ? 124.284 140.002 141.567 1.00 59.69  ? 640 MET C CA  1 
ATOM   14005 C C   . MET C 1 640 ? 125.634 139.593 140.971 1.00 68.16  ? 640 MET C C   1 
ATOM   14006 O O   . MET C 1 640 ? 126.057 140.190 139.990 1.00 70.22  ? 640 MET C O   1 
ATOM   14007 C CB  . MET C 1 640 ? 124.426 140.717 142.916 1.00 65.54  ? 640 MET C CB  1 
ATOM   14008 C CG  . MET C 1 640 ? 125.286 141.983 142.872 1.00 69.39  ? 640 MET C CG  1 
ATOM   14009 S SD  . MET C 1 640 ? 127.036 141.819 143.287 1.00 82.07  ? 640 MET C SD  1 
ATOM   14010 C CE  . MET C 1 640 ? 126.949 141.385 145.040 1.00 66.57  ? 640 MET C CE  1 
ATOM   14011 N N   . LEU C 1 641 ? 126.273 138.531 141.468 1.00 72.65  ? 641 LEU C N   1 
ATOM   14012 C CA  . LEU C 1 641 ? 127.531 138.017 140.915 1.00 64.10  ? 641 LEU C CA  1 
ATOM   14013 C C   . LEU C 1 641 ? 127.356 137.525 139.478 1.00 61.28  ? 641 LEU C C   1 
ATOM   14014 O O   . LEU C 1 641 ? 128.164 137.849 138.616 1.00 69.04  ? 641 LEU C O   1 
ATOM   14015 C CB  . LEU C 1 641 ? 128.072 136.891 141.813 1.00 70.89  ? 641 LEU C CB  1 
ATOM   14016 C CG  . LEU C 1 641 ? 129.136 137.351 142.824 1.00 72.69  ? 641 LEU C CG  1 
ATOM   14017 C CD1 . LEU C 1 641 ? 128.676 138.461 143.759 1.00 63.71  ? 641 LEU C CD1 1 
ATOM   14018 C CD2 . LEU C 1 641 ? 129.547 136.163 143.688 1.00 73.43  ? 641 LEU C CD2 1 
ATOM   14019 N N   . ILE C 1 642 ? 126.300 136.775 139.184 1.00 67.07  ? 642 ILE C N   1 
ATOM   14020 C CA  . ILE C 1 642 ? 126.027 136.279 137.830 1.00 67.49  ? 642 ILE C CA  1 
ATOM   14021 C C   . ILE C 1 642 ? 125.671 137.410 136.863 1.00 67.35  ? 642 ILE C C   1 
ATOM   14022 O O   . ILE C 1 642 ? 126.140 137.395 135.727 1.00 76.05  ? 642 ILE C O   1 
ATOM   14023 C CB  . ILE C 1 642 ? 124.977 135.154 137.908 1.00 68.91  ? 642 ILE C CB  1 
ATOM   14024 C CG1 . ILE C 1 642 ? 125.688 133.876 138.411 1.00 66.91  ? 642 ILE C CG1 1 
ATOM   14025 C CG2 . ILE C 1 642 ? 124.299 134.892 136.563 1.00 65.81  ? 642 ILE C CG2 1 
ATOM   14026 C CD1 . ILE C 1 642 ? 124.757 132.799 138.955 1.00 67.10  ? 642 ILE C CD1 1 
ATOM   14027 N N   . ALA C 1 643 ? 124.922 138.433 137.285 1.00 65.94  ? 643 ALA C N   1 
ATOM   14028 C CA  . ALA C 1 643 ? 124.684 139.631 136.485 1.00 61.18  ? 643 ALA C CA  1 
ATOM   14029 C C   . ALA C 1 643 ? 125.998 140.357 136.146 1.00 70.60  ? 643 ALA C C   1 
ATOM   14030 O O   . ALA C 1 643 ? 126.248 140.627 134.974 1.00 80.51  ? 643 ALA C O   1 
ATOM   14031 C CB  . ALA C 1 643 ? 123.699 140.539 137.218 1.00 57.77  ? 643 ALA C CB  1 
ATOM   14032 N N   . LEU C 1 644 ? 126.880 140.587 137.122 1.00 78.52  ? 644 LEU C N   1 
ATOM   14033 C CA  . LEU C 1 644 ? 128.204 141.176 136.906 1.00 69.82  ? 644 LEU C CA  1 
ATOM   14034 C C   . LEU C 1 644 ? 129.075 140.340 135.964 1.00 69.75  ? 644 LEU C C   1 
ATOM   14035 O O   . LEU C 1 644 ? 129.649 140.901 135.036 1.00 82.17  ? 644 LEU C O   1 
ATOM   14036 C CB  . LEU C 1 644 ? 128.914 141.368 138.254 1.00 72.86  ? 644 LEU C CB  1 
ATOM   14037 C CG  . LEU C 1 644 ? 128.803 142.783 138.838 1.00 77.22  ? 644 LEU C CG  1 
ATOM   14038 C CD1 . LEU C 1 644 ? 127.375 143.291 138.997 1.00 78.40  ? 644 LEU C CD1 1 
ATOM   14039 C CD2 . LEU C 1 644 ? 129.445 142.784 140.216 1.00 78.76  ? 644 LEU C CD2 1 
ATOM   14040 N N   . MET C 1 645 ? 129.164 139.019 136.133 1.00 72.92  ? 645 MET C N   1 
ATOM   14041 C CA  . MET C 1 645 ? 129.891 138.157 135.190 1.00 76.95  ? 645 MET C CA  1 
ATOM   14042 C C   . MET C 1 645 ? 129.337 138.271 133.773 1.00 81.17  ? 645 MET C C   1 
ATOM   14043 O O   . MET C 1 645 ? 130.105 138.401 132.831 1.00 83.06  ? 645 MET C O   1 
ATOM   14044 C CB  . MET C 1 645 ? 129.833 136.691 135.619 1.00 74.40  ? 645 MET C CB  1 
ATOM   14045 C CG  . MET C 1 645 ? 130.637 136.416 136.883 1.00 81.85  ? 645 MET C CG  1 
ATOM   14046 S SD  . MET C 1 645 ? 130.446 134.722 137.467 1.00 94.00  ? 645 MET C SD  1 
ATOM   14047 C CE  . MET C 1 645 ? 131.065 134.968 139.148 1.00 82.05  ? 645 MET C CE  1 
ATOM   14048 N N   . SER C 1 646 ? 128.016 138.272 133.603 1.00 81.89  ? 646 SER C N   1 
ATOM   14049 C CA  . SER C 1 646 ? 127.404 138.343 132.276 1.00 81.03  ? 646 SER C CA  1 
ATOM   14050 C C   . SER C 1 646 ? 127.775 139.613 131.493 1.00 85.15  ? 646 SER C C   1 
ATOM   14051 O O   . SER C 1 646 ? 127.978 139.529 130.284 1.00 87.16  ? 646 SER C O   1 
ATOM   14052 C CB  . SER C 1 646 ? 125.888 138.171 132.383 1.00 76.66  ? 646 SER C CB  1 
ATOM   14053 O OG  . SER C 1 646 ? 125.232 139.351 132.808 1.00 78.96  ? 646 SER C OG  1 
ATOM   14054 N N   . GLU C 1 647 ? 127.920 140.778 132.139 1.00 90.30  ? 647 GLU C N   1 
ATOM   14055 C CA  . GLU C 1 647 ? 128.354 141.999 131.446 1.00 92.76  ? 647 GLU C CA  1 
ATOM   14056 C C   . GLU C 1 647 ? 129.881 142.124 131.338 1.00 94.62  ? 647 GLU C C   1 
ATOM   14057 O O   . GLU C 1 647 ? 130.387 142.553 130.304 1.00 99.01  ? 647 GLU C O   1 
ATOM   14058 C CB  . GLU C 1 647 ? 127.724 143.247 132.088 1.00 92.30  ? 647 GLU C CB  1 
ATOM   14059 C CG  . GLU C 1 647 ? 128.045 144.513 131.257 1.00 101.30 ? 647 GLU C CG  1 
ATOM   14060 C CD  . GLU C 1 647 ? 127.100 145.710 131.471 1.00 103.04 ? 647 GLU C CD  1 
ATOM   14061 O OE1 . GLU C 1 647 ? 125.975 145.545 131.986 1.00 98.81  ? 647 GLU C OE1 1 
ATOM   14062 O OE2 . GLU C 1 647 ? 127.471 146.857 131.146 1.00 99.26  ? 647 GLU C OE2 1 
ATOM   14063 N N   . THR C 1 648 ? 130.629 141.763 132.379 1.00 78.23  ? 648 THR C N   1 
ATOM   14064 C CA  . THR C 1 648 ? 132.079 142.023 132.462 1.00 80.26  ? 648 THR C CA  1 
ATOM   14065 C C   . THR C 1 648 ? 132.980 140.908 131.913 1.00 80.71  ? 648 THR C C   1 
ATOM   14066 O O   . THR C 1 648 ? 134.124 141.186 131.571 1.00 81.80  ? 648 THR C O   1 
ATOM   14067 C CB  . THR C 1 648 ? 132.508 142.357 133.897 1.00 78.59  ? 648 THR C CB  1 
ATOM   14068 O OG1 . THR C 1 648 ? 132.252 141.281 134.755 1.00 81.80  ? 648 THR C OG1 1 
ATOM   14069 C CG2 . THR C 1 648 ? 131.822 143.589 134.477 1.00 75.32  ? 648 THR C CG2 1 
ATOM   14070 N N   . VAL C 1 649 ? 132.509 139.663 131.793 1.00 82.30  ? 649 VAL C N   1 
ATOM   14071 C CA  . VAL C 1 649 ? 133.311 138.547 131.215 1.00 83.41  ? 649 VAL C CA  1 
ATOM   14072 C C   . VAL C 1 649 ? 132.819 138.388 129.782 1.00 87.67  ? 649 VAL C C   1 
ATOM   14073 O O   . VAL C 1 649 ? 132.107 137.402 129.503 1.00 87.26  ? 649 VAL C O   1 
ATOM   14074 C CB  . VAL C 1 649 ? 133.154 137.248 132.029 1.00 79.62  ? 649 VAL C CB  1 
ATOM   14075 C CG1 . VAL C 1 649 ? 134.097 136.159 131.538 1.00 79.31  ? 649 VAL C CG1 1 
ATOM   14076 C CG2 . VAL C 1 649 ? 133.354 137.493 133.517 1.00 80.95  ? 649 VAL C CG2 1 
ATOM   14077 N N   . ASN C 1 650 ? 133.174 139.337 128.918 1.00 90.51  ? 650 ASN C N   1 
ATOM   14078 C CA  . ASN C 1 650 ? 132.608 139.313 127.546 1.00 87.40  ? 650 ASN C CA  1 
ATOM   14079 C C   . ASN C 1 650 ? 133.651 138.902 126.504 1.00 86.89  ? 650 ASN C C   1 
ATOM   14080 O O   . ASN C 1 650 ? 133.225 138.733 125.344 1.00 84.00  ? 650 ASN C O   1 
ATOM   14081 C CB  . ASN C 1 650 ? 131.991 140.667 127.186 1.00 90.41  ? 650 ASN C CB  1 
ATOM   14082 C CG  . ASN C 1 650 ? 132.939 141.822 127.430 1.00 94.30  ? 650 ASN C CG  1 
ATOM   14083 O OD1 . ASN C 1 650 ? 134.137 141.620 127.615 1.00 97.53  ? 650 ASN C OD1 1 
ATOM   14084 N ND2 . ASN C 1 650 ? 132.413 143.036 127.431 1.00 89.13  ? 650 ASN C ND2 1 
ATOM   14085 N N   . HIS C 1 651 ? 134.930 138.776 126.838 1.00 92.25  ? 651 HIS C N   1 
ATOM   14086 C CA  . HIS C 1 651 ? 135.987 138.473 125.830 1.00 93.13  ? 651 HIS C CA  1 
ATOM   14087 C C   . HIS C 1 651 ? 136.499 139.713 125.092 1.00 93.03  ? 651 HIS C C   1 
ATOM   14088 O O   . HIS C 1 651 ? 137.450 139.551 124.331 1.00 88.40  ? 651 HIS C O   1 
ATOM   14089 C CB  . HIS C 1 651 ? 135.540 137.307 124.940 1.00 91.15  ? 651 HIS C CB  1 
ATOM   14090 C CG  . HIS C 1 651 ? 135.242 136.063 125.704 1.00 91.91  ? 651 HIS C CG  1 
ATOM   14091 N ND1 . HIS C 1 651 ? 136.131 135.516 126.600 1.00 90.52  ? 651 HIS C ND1 1 
ATOM   14092 C CD2 . HIS C 1 651 ? 134.160 135.259 125.712 1.00 92.65  ? 651 HIS C CD2 1 
ATOM   14093 C CE1 . HIS C 1 651 ? 135.604 134.435 127.132 1.00 90.40  ? 651 HIS C CE1 1 
ATOM   14094 N NE2 . HIS C 1 651 ? 134.399 134.255 126.603 1.00 87.23  ? 651 HIS C NE2 1 
ATOM   14095 N N   . VAL C 1 652 ? 135.911 140.895 125.300 1.00 102.31 ? 652 VAL C N   1 
ATOM   14096 C CA  . VAL C 1 652 ? 136.471 142.121 124.717 1.00 98.34  ? 652 VAL C CA  1 
ATOM   14097 C C   . VAL C 1 652 ? 137.972 142.163 125.028 1.00 99.19  ? 652 VAL C C   1 
ATOM   14098 O O   . VAL C 1 652 ? 138.378 141.902 126.159 1.00 98.23  ? 652 VAL C O   1 
ATOM   14099 C CB  . VAL C 1 652 ? 135.739 143.365 125.251 1.00 96.77  ? 652 VAL C CB  1 
ATOM   14100 C CG1 . VAL C 1 652 ? 136.383 144.674 124.781 1.00 97.31  ? 652 VAL C CG1 1 
ATOM   14101 C CG2 . VAL C 1 652 ? 134.285 143.389 124.774 1.00 96.64  ? 652 VAL C CG2 1 
ATOM   14102 N N   . ALA C 1 653 ? 138.810 142.457 124.033 1.00 108.54 ? 653 ALA C N   1 
ATOM   14103 C CA  . ALA C 1 653 ? 140.260 142.511 124.208 1.00 108.60 ? 653 ALA C CA  1 
ATOM   14104 C C   . ALA C 1 653 ? 140.656 143.630 125.184 1.00 107.17 ? 653 ALA C C   1 
ATOM   14105 O O   . ALA C 1 653 ? 140.080 144.716 125.155 1.00 105.39 ? 653 ALA C O   1 
ATOM   14106 C CB  . ALA C 1 653 ? 140.916 142.682 122.836 1.00 106.05 ? 653 ALA C CB  1 
ATOM   14107 N N   . ASP C 1 654 ? 141.624 143.376 126.062 1.00 106.66 ? 654 ASP C N   1 
ATOM   14108 C CA  . ASP C 1 654 ? 141.867 144.233 127.223 1.00 105.79 ? 654 ASP C CA  1 
ATOM   14109 C C   . ASP C 1 654 ? 142.348 145.649 126.835 1.00 106.70 ? 654 ASP C C   1 
ATOM   14110 O O   . ASP C 1 654 ? 143.423 145.823 126.260 1.00 100.92 ? 654 ASP C O   1 
ATOM   14111 C CB  . ASP C 1 654 ? 142.849 143.533 128.174 1.00 106.60 ? 654 ASP C CB  1 
ATOM   14112 C CG  . ASP C 1 654 ? 143.006 144.264 129.513 1.00 109.56 ? 654 ASP C CG  1 
ATOM   14113 O OD1 . ASP C 1 654 ? 142.240 145.212 129.787 1.00 108.24 ? 654 ASP C OD1 1 
ATOM   14114 O OD2 . ASP C 1 654 ? 143.927 143.926 130.286 1.00 107.00 ? 654 ASP C OD2 1 
ATOM   14115 N N   . ASN C 1 655 ? 141.566 146.682 127.192 1.00 104.95 ? 655 ASN C N   1 
ATOM   14116 C CA  . ASN C 1 655 ? 141.904 148.088 126.802 1.00 102.07 ? 655 ASN C CA  1 
ATOM   14117 C C   . ASN C 1 655 ? 142.561 148.843 127.965 1.00 104.20 ? 655 ASN C C   1 
ATOM   14118 O O   . ASN C 1 655 ? 142.430 150.082 128.000 1.00 105.89 ? 655 ASN C O   1 
ATOM   14119 C CB  . ASN C 1 655 ? 140.674 148.841 126.287 1.00 101.08 ? 655 ASN C CB  1 
ATOM   14120 C CG  . ASN C 1 655 ? 140.100 148.241 125.021 1.00 109.41 ? 655 ASN C CG  1 
ATOM   14121 O OD1 . ASN C 1 655 ? 139.023 148.633 124.576 1.00 109.61 ? 655 ASN C OD1 1 
ATOM   14122 N ND2 . ASN C 1 655 ? 140.809 147.291 124.434 1.00 110.97 ? 655 ASN C ND2 1 
ATOM   14123 N N   . SER C 1 656 ? 143.247 148.140 128.865 1.00 95.66  ? 656 SER C N   1 
ATOM   14124 C CA  . SER C 1 656 ? 143.939 148.716 130.016 1.00 89.24  ? 656 SER C CA  1 
ATOM   14125 C C   . SER C 1 656 ? 145.268 149.408 129.718 1.00 90.27  ? 656 SER C C   1 
ATOM   14126 O O   . SER C 1 656 ? 145.524 150.454 130.306 1.00 95.03  ? 656 SER C O   1 
ATOM   14127 C CB  . SER C 1 656 ? 144.156 147.649 131.086 1.00 93.22  ? 656 SER C CB  1 
ATOM   14128 O OG  . SER C 1 656 ? 144.962 146.620 130.564 1.00 98.66  ? 656 SER C OG  1 
ATOM   14129 N N   . TRP C 1 657 ? 146.084 148.923 128.781 1.00 82.07  ? 657 TRP C N   1 
ATOM   14130 C CA  . TRP C 1 657 ? 147.323 149.607 128.376 1.00 85.23  ? 657 TRP C CA  1 
ATOM   14131 C C   . TRP C 1 657 ? 147.065 151.019 127.846 1.00 84.90  ? 657 TRP C C   1 
ATOM   14132 O O   . TRP C 1 657 ? 147.747 151.972 128.204 1.00 89.28  ? 657 TRP C O   1 
ATOM   14133 C CB  . TRP C 1 657 ? 148.061 148.747 127.348 1.00 81.06  ? 657 TRP C CB  1 
ATOM   14134 C CG  . TRP C 1 657 ? 149.224 149.403 126.669 1.00 84.50  ? 657 TRP C CG  1 
ATOM   14135 C CD1 . TRP C 1 657 ? 150.493 149.453 127.132 1.00 85.70  ? 657 TRP C CD1 1 
ATOM   14136 C CD2 . TRP C 1 657 ? 149.245 150.118 125.397 1.00 90.69  ? 657 TRP C CD2 1 
ATOM   14137 N NE1 . TRP C 1 657 ? 151.287 150.156 126.251 1.00 84.29  ? 657 TRP C NE1 1 
ATOM   14138 C CE2 . TRP C 1 657 ? 150.569 150.589 125.161 1.00 90.65  ? 657 TRP C CE2 1 
ATOM   14139 C CE3 . TRP C 1 657 ? 148.283 150.380 124.398 1.00 88.55  ? 657 TRP C CE3 1 
ATOM   14140 C CZ2 . TRP C 1 657 ? 150.914 151.300 124.004 1.00 85.72  ? 657 TRP C CZ2 1 
ATOM   14141 C CZ3 . TRP C 1 657 ? 148.621 151.092 123.236 1.00 85.60  ? 657 TRP C CZ3 1 
ATOM   14142 C CH2 . TRP C 1 657 ? 149.931 151.561 123.038 1.00 82.60  ? 657 TRP C CH2 1 
ATOM   14143 N N   . SER C 1 658 ? 146.015 151.184 127.052 1.00 77.42  ? 658 SER C N   1 
ATOM   14144 C CA  . SER C 1 658 ? 145.628 152.473 126.464 1.00 69.87  ? 658 SER C CA  1 
ATOM   14145 C C   . SER C 1 658 ? 144.949 153.407 127.468 1.00 76.28  ? 658 SER C C   1 
ATOM   14146 O O   . SER C 1 658 ? 145.137 154.617 127.405 1.00 83.36  ? 658 SER C O   1 
ATOM   14147 C CB  . SER C 1 658 ? 144.773 152.253 125.217 1.00 70.74  ? 658 SER C CB  1 
ATOM   14148 O OG  . SER C 1 658 ? 143.481 151.779 125.531 1.00 80.87  ? 658 SER C OG  1 
ATOM   14149 N N   . ILE C 1 659 ? 144.164 152.884 128.405 1.00 69.80  ? 659 ILE C N   1 
ATOM   14150 C CA  . ILE C 1 659 ? 143.594 153.706 129.478 1.00 67.00  ? 659 ILE C CA  1 
ATOM   14151 C C   . ILE C 1 659 ? 144.714 154.156 130.424 1.00 66.86  ? 659 ILE C C   1 
ATOM   14152 O O   . ILE C 1 659 ? 144.725 155.303 130.855 1.00 75.38  ? 659 ILE C O   1 
ATOM   14153 C CB  . ILE C 1 659 ? 142.439 152.962 130.168 1.00 69.70  ? 659 ILE C CB  1 
ATOM   14154 C CG1 . ILE C 1 659 ? 141.252 152.771 129.213 1.00 70.18  ? 659 ILE C CG1 1 
ATOM   14155 C CG2 . ILE C 1 659 ? 141.986 153.705 131.434 1.00 71.87  ? 659 ILE C CG2 1 
ATOM   14156 C CD1 . ILE C 1 659 ? 140.198 151.790 129.719 1.00 69.77  ? 659 ILE C CD1 1 
ATOM   14157 N N   . TRP C 1 660 ? 145.730 153.330 130.665 1.00 57.69  ? 660 TRP C N   1 
ATOM   14158 C CA  . TRP C 1 660 ? 146.942 153.743 131.364 1.00 62.85  ? 660 TRP C CA  1 
ATOM   14159 C C   . TRP C 1 660 ? 147.747 154.802 130.601 1.00 66.83  ? 660 TRP C C   1 
ATOM   14160 O O   . TRP C 1 660 ? 148.152 155.801 131.186 1.00 76.34  ? 660 TRP C O   1 
ATOM   14161 C CB  . TRP C 1 660 ? 147.779 152.511 131.684 1.00 66.34  ? 660 TRP C CB  1 
ATOM   14162 C CG  . TRP C 1 660 ? 149.140 152.822 132.200 1.00 65.92  ? 660 TRP C CG  1 
ATOM   14163 C CD1 . TRP C 1 660 ? 149.411 153.486 133.341 1.00 62.83  ? 660 TRP C CD1 1 
ATOM   14164 C CD2 . TRP C 1 660 ? 150.425 152.577 131.563 1.00 64.71  ? 660 TRP C CD2 1 
ATOM   14165 N NE1 . TRP C 1 660 ? 150.772 153.643 133.467 1.00 55.94  ? 660 TRP C NE1 1 
ATOM   14166 C CE2 . TRP C 1 660 ? 151.446 153.090 132.407 1.00 63.10  ? 660 TRP C CE2 1 
ATOM   14167 C CE3 . TRP C 1 660 ? 150.826 151.982 130.353 1.00 69.52  ? 660 TRP C CE3 1 
ATOM   14168 C CZ2 . TRP C 1 660 ? 152.804 152.990 132.084 1.00 67.17  ? 660 TRP C CZ2 1 
ATOM   14169 C CZ3 . TRP C 1 660 ? 152.182 151.891 130.009 1.00 70.23  ? 660 TRP C CZ3 1 
ATOM   14170 C CH2 . TRP C 1 660 ? 153.170 152.386 130.873 1.00 68.36  ? 660 TRP C CH2 1 
ATOM   14171 N N   . LYS C 1 661 ? 147.918 154.683 129.283 1.00 67.28  ? 661 LYS C N   1 
ATOM   14172 C CA  . LYS C 1 661 ? 148.518 155.738 128.449 1.00 60.71  ? 661 LYS C CA  1 
ATOM   14173 C C   . LYS C 1 661 ? 147.762 157.063 128.539 1.00 62.82  ? 661 LYS C C   1 
ATOM   14174 O O   . LYS C 1 661 ? 148.396 158.108 128.583 1.00 65.99  ? 661 LYS C O   1 
ATOM   14175 C CB  . LYS C 1 661 ? 148.590 155.262 126.995 1.00 58.01  ? 661 LYS C CB  1 
ATOM   14176 C CG  . LYS C 1 661 ? 149.728 154.267 126.739 1.00 62.18  ? 661 LYS C CG  1 
ATOM   14177 C CD  . LYS C 1 661 ? 151.028 154.997 126.397 1.00 70.03  ? 661 LYS C CD  1 
ATOM   14178 C CE  . LYS C 1 661 ? 152.125 153.993 126.048 1.00 74.58  ? 661 LYS C CE  1 
ATOM   14179 N NZ  . LYS C 1 661 ? 153.266 154.646 125.358 1.00 67.90  ? 661 LYS C NZ  1 
ATOM   14180 N N   . LEU C 1 662 ? 146.433 157.062 128.641 1.00 58.00  ? 662 LEU C N   1 
ATOM   14181 C CA  . LEU C 1 662 ? 145.646 158.272 128.895 1.00 52.44  ? 662 LEU C CA  1 
ATOM   14182 C C   . LEU C 1 662 ? 145.856 158.829 130.306 1.00 68.79  ? 662 LEU C C   1 
ATOM   14183 O O   . LEU C 1 662 ? 145.988 160.037 130.465 1.00 78.01  ? 662 LEU C O   1 
ATOM   14184 C CB  . LEU C 1 662 ? 144.170 157.973 128.593 1.00 52.82  ? 662 LEU C CB  1 
ATOM   14185 C CG  . LEU C 1 662 ? 143.206 159.146 128.829 1.00 58.93  ? 662 LEU C CG  1 
ATOM   14186 C CD1 . LEU C 1 662 ? 143.413 160.299 127.857 1.00 62.25  ? 662 LEU C CD1 1 
ATOM   14187 C CD2 . LEU C 1 662 ? 141.780 158.651 128.671 1.00 62.21  ? 662 LEU C CD2 1 
ATOM   14188 N N   . GLN C 1 663 ? 145.958 157.990 131.335 1.00 62.30  ? 663 GLN C N   1 
ATOM   14189 C CA  . GLN C 1 663 ? 146.302 158.433 132.686 1.00 44.14  ? 663 GLN C CA  1 
ATOM   14190 C C   . GLN C 1 663 ? 147.670 159.118 132.726 1.00 59.13  ? 663 GLN C C   1 
ATOM   14191 O O   . GLN C 1 663 ? 147.805 160.186 133.319 1.00 62.72  ? 663 GLN C O   1 
ATOM   14192 C CB  . GLN C 1 663 ? 146.272 157.244 133.646 1.00 49.05  ? 663 GLN C CB  1 
ATOM   14193 C CG  . GLN C 1 663 ? 144.841 156.798 133.947 1.00 57.74  ? 663 GLN C CG  1 
ATOM   14194 C CD  . GLN C 1 663 ? 144.781 155.580 134.848 1.00 63.94  ? 663 GLN C CD  1 
ATOM   14195 O OE1 . GLN C 1 663 ? 145.769 154.929 135.147 1.00 58.64  ? 663 GLN C OE1 1 
ATOM   14196 N NE2 . GLN C 1 663 ? 143.612 155.236 135.331 1.00 64.63  ? 663 GLN C NE2 1 
ATOM   14197 N N   . LYS C 1 664 ? 148.675 158.562 132.037 1.00 68.27  ? 664 LYS C N   1 
ATOM   14198 C CA  . LYS C 1 664 ? 149.982 159.207 131.862 1.00 55.97  ? 664 LYS C CA  1 
ATOM   14199 C C   . LYS C 1 664 ? 149.922 160.492 131.038 1.00 61.79  ? 664 LYS C C   1 
ATOM   14200 O O   . LYS C 1 664 ? 150.600 161.443 131.394 1.00 72.47  ? 664 LYS C O   1 
ATOM   14201 C CB  . LYS C 1 664 ? 150.989 158.231 131.260 1.00 53.05  ? 664 LYS C CB  1 
ATOM   14202 C CG  . LYS C 1 664 ? 151.276 157.062 132.204 1.00 56.41  ? 664 LYS C CG  1 
ATOM   14203 C CD  . LYS C 1 664 ? 152.687 156.513 132.008 1.00 61.18  ? 664 LYS C CD  1 
ATOM   14204 C CE  . LYS C 1 664 ? 152.922 156.003 130.584 1.00 64.10  ? 664 LYS C CE  1 
ATOM   14205 N NZ  . LYS C 1 664 ? 154.335 155.587 130.394 1.00 69.07  ? 664 LYS C NZ  1 
ATOM   14206 N N   . ALA C 1 665 ? 149.083 160.579 130.007 1.00 48.59  ? 665 ALA C N   1 
ATOM   14207 C CA  . ALA C 1 665 ? 148.845 161.816 129.267 1.00 45.38  ? 665 ALA C CA  1 
ATOM   14208 C C   . ALA C 1 665 ? 148.255 162.927 130.141 1.00 57.27  ? 665 ALA C C   1 
ATOM   14209 O O   . ALA C 1 665 ? 148.779 164.031 130.159 1.00 68.67  ? 665 ALA C O   1 
ATOM   14210 C CB  . ALA C 1 665 ? 147.936 161.525 128.076 1.00 55.42  ? 665 ALA C CB  1 
ATOM   14211 N N   . ILE C 1 666 ? 147.212 162.648 130.920 1.00 66.86  ? 666 ILE C N   1 
ATOM   14212 C CA  . ILE C 1 666 ? 146.604 163.614 131.849 1.00 59.79  ? 666 ILE C CA  1 
ATOM   14213 C C   . ILE C 1 666 ? 147.624 164.086 132.895 1.00 58.29  ? 666 ILE C C   1 
ATOM   14214 O O   . ILE C 1 666 ? 147.722 165.275 133.183 1.00 65.58  ? 666 ILE C O   1 
ATOM   14215 C CB  . ILE C 1 666 ? 145.359 162.980 132.502 1.00 58.52  ? 666 ILE C CB  1 
ATOM   14216 C CG1 . ILE C 1 666 ? 144.238 162.778 131.467 1.00 52.13  ? 666 ILE C CG1 1 
ATOM   14217 C CG2 . ILE C 1 666 ? 144.831 163.833 133.660 1.00 66.01  ? 666 ILE C CG2 1 
ATOM   14218 C CD1 . ILE C 1 666 ? 143.206 161.738 131.892 1.00 58.65  ? 666 ILE C CD1 1 
ATOM   14219 N N   . SER C 1 667 ? 148.427 163.162 133.426 1.00 58.63  ? 667 SER C N   1 
ATOM   14220 C CA  . SER C 1 667 ? 149.511 163.443 134.371 1.00 57.19  ? 667 SER C CA  1 
ATOM   14221 C C   . SER C 1 667 ? 150.574 164.370 133.782 1.00 55.40  ? 667 SER C C   1 
ATOM   14222 O O   . SER C 1 667 ? 150.902 165.391 134.379 1.00 58.75  ? 667 SER C O   1 
ATOM   14223 C CB  . SER C 1 667 ? 150.123 162.114 134.805 1.00 61.39  ? 667 SER C CB  1 
ATOM   14224 O OG  . SER C 1 667 ? 151.212 162.323 135.663 1.00 63.85  ? 667 SER C OG  1 
ATOM   14225 N N   . VAL C 1 668 ? 151.062 164.083 132.572 1.00 65.67  ? 668 VAL C N   1 
ATOM   14226 C CA  . VAL C 1 668 ? 152.013 164.920 131.825 1.00 65.53  ? 668 VAL C CA  1 
ATOM   14227 C C   . VAL C 1 668 ? 151.490 166.331 131.615 1.00 70.24  ? 668 VAL C C   1 
ATOM   14228 O O   . VAL C 1 668 ? 152.181 167.291 131.937 1.00 78.72  ? 668 VAL C O   1 
ATOM   14229 C CB  . VAL C 1 668 ? 152.326 164.257 130.474 1.00 59.88  ? 668 VAL C CB  1 
ATOM   14230 C CG1 . VAL C 1 668 ? 152.877 165.190 129.402 1.00 67.15  ? 668 VAL C CG1 1 
ATOM   14231 C CG2 . VAL C 1 668 ? 153.356 163.160 130.686 1.00 62.97  ? 668 VAL C CG2 1 
ATOM   14232 N N   . LEU C 1 669 ? 150.278 166.471 131.089 1.00 63.77  ? 669 LEU C N   1 
ATOM   14233 C CA  . LEU C 1 669 ? 149.735 167.771 130.715 1.00 60.14  ? 669 LEU C CA  1 
ATOM   14234 C C   . LEU C 1 669 ? 149.463 168.659 131.929 1.00 65.98  ? 669 LEU C C   1 
ATOM   14235 O O   . LEU C 1 669 ? 149.466 169.878 131.800 1.00 75.49  ? 669 LEU C O   1 
ATOM   14236 C CB  . LEU C 1 669 ? 148.472 167.543 129.880 1.00 65.80  ? 669 LEU C CB  1 
ATOM   14237 C CG  . LEU C 1 669 ? 148.742 166.816 128.555 1.00 66.00  ? 669 LEU C CG  1 
ATOM   14238 C CD1 . LEU C 1 669 ? 147.439 166.266 128.004 1.00 66.40  ? 669 LEU C CD1 1 
ATOM   14239 C CD2 . LEU C 1 669 ? 149.362 167.747 127.529 1.00 63.71  ? 669 LEU C CD2 1 
ATOM   14240 N N   . GLU C 1 670 ? 149.274 168.079 133.110 1.00 79.19  ? 670 GLU C N   1 
ATOM   14241 C CA  . GLU C 1 670 ? 149.289 168.792 134.384 1.00 77.84  ? 670 GLU C CA  1 
ATOM   14242 C C   . GLU C 1 670 ? 150.700 169.163 134.859 1.00 77.81  ? 670 GLU C C   1 
ATOM   14243 O O   . GLU C 1 670 ? 150.941 170.328 135.175 1.00 77.90  ? 670 GLU C O   1 
ATOM   14244 C CB  . GLU C 1 670 ? 148.563 167.949 135.438 1.00 73.17  ? 670 GLU C CB  1 
ATOM   14245 C CG  . GLU C 1 670 ? 147.048 168.120 135.329 1.00 79.06  ? 670 GLU C CG  1 
ATOM   14246 C CD  . GLU C 1 670 ? 146.646 169.578 135.575 1.00 89.64  ? 670 GLU C CD  1 
ATOM   14247 O OE1 . GLU C 1 670 ? 147.088 170.155 136.591 1.00 89.29  ? 670 GLU C OE1 1 
ATOM   14248 O OE2 . GLU C 1 670 ? 145.935 170.185 134.739 1.00 93.46  ? 670 GLU C OE2 1 
ATOM   14249 N N   . MET C 1 671 ? 151.649 168.226 134.854 1.00 70.39  ? 671 MET C N   1 
ATOM   14250 C CA  . MET C 1 671 ? 153.036 168.484 135.252 1.00 69.45  ? 671 MET C CA  1 
ATOM   14251 C C   . MET C 1 671 ? 153.749 169.542 134.413 1.00 67.77  ? 671 MET C C   1 
ATOM   14252 O O   . MET C 1 671 ? 154.584 170.272 134.939 1.00 79.28  ? 671 MET C O   1 
ATOM   14253 C CB  . MET C 1 671 ? 153.852 167.197 135.163 1.00 67.53  ? 671 MET C CB  1 
ATOM   14254 C CG  . MET C 1 671 ? 153.549 166.234 136.300 1.00 64.09  ? 671 MET C CG  1 
ATOM   14255 S SD  . MET C 1 671 ? 154.743 164.897 136.397 1.00 67.34  ? 671 MET C SD  1 
ATOM   14256 C CE  . MET C 1 671 ? 154.354 163.951 134.914 1.00 70.66  ? 671 MET C CE  1 
ATOM   14257 N N   . GLU C 1 672 ? 153.439 169.675 133.127 1.00 73.88  ? 672 GLU C N   1 
ATOM   14258 C CA  . GLU C 1 672 ? 154.040 170.694 132.260 1.00 76.45  ? 672 GLU C CA  1 
ATOM   14259 C C   . GLU C 1 672 ? 153.777 172.141 132.702 1.00 80.94  ? 672 GLU C C   1 
ATOM   14260 O O   . GLU C 1 672 ? 154.536 173.028 132.329 1.00 77.09  ? 672 GLU C O   1 
ATOM   14261 C CB  . GLU C 1 672 ? 153.516 170.521 130.834 1.00 75.01  ? 672 GLU C CB  1 
ATOM   14262 C CG  . GLU C 1 672 ? 154.240 169.412 130.070 1.00 77.20  ? 672 GLU C CG  1 
ATOM   14263 C CD  . GLU C 1 672 ? 153.832 169.453 128.597 1.00 85.84  ? 672 GLU C CD  1 
ATOM   14264 O OE1 . GLU C 1 672 ? 152.634 169.638 128.307 1.00 85.17  ? 672 GLU C OE1 1 
ATOM   14265 O OE2 . GLU C 1 672 ? 154.702 169.347 127.708 1.00 85.99  ? 672 GLU C OE2 1 
ATOM   14266 N N   . ASN C 1 673 ? 152.738 172.403 133.501 1.00 88.96  ? 673 ASN C N   1 
ATOM   14267 C CA  . ASN C 1 673 ? 152.465 173.734 134.056 1.00 86.04  ? 673 ASN C CA  1 
ATOM   14268 C C   . ASN C 1 673 ? 153.304 174.044 135.302 1.00 85.70  ? 673 ASN C C   1 
ATOM   14269 O O   . ASN C 1 673 ? 153.262 175.161 135.805 1.00 91.09  ? 673 ASN C O   1 
ATOM   14270 C CB  . ASN C 1 673 ? 150.972 173.882 134.378 1.00 88.08  ? 673 ASN C CB  1 
ATOM   14271 C CG  . ASN C 1 673 ? 150.084 173.405 133.257 1.00 86.53  ? 673 ASN C CG  1 
ATOM   14272 O OD1 . ASN C 1 673 ? 149.887 174.064 132.248 1.00 85.00  ? 673 ASN C OD1 1 
ATOM   14273 N ND2 . ASN C 1 673 ? 149.568 172.213 133.394 1.00 83.18  ? 673 ASN C ND2 1 
ATOM   14274 N N   . GLY C 1 674 ? 154.053 173.080 135.832 1.00 84.65  ? 674 GLY C N   1 
ATOM   14275 C CA  . GLY C 1 674 ? 154.724 173.210 137.117 1.00 83.46  ? 674 GLY C CA  1 
ATOM   14276 C C   . GLY C 1 674 ? 153.723 173.159 138.266 1.00 86.28  ? 674 GLY C C   1 
ATOM   14277 O O   . GLY C 1 674 ? 152.850 172.297 138.305 1.00 90.01  ? 674 GLY C O   1 
ATOM   14278 N N   . TYR C 1 675 ? 153.853 174.087 139.204 1.00 87.36  ? 675 TYR C N   1 
ATOM   14279 C CA  . TYR C 1 675 ? 153.052 174.157 140.424 1.00 88.28  ? 675 TYR C CA  1 
ATOM   14280 C C   . TYR C 1 675 ? 152.334 175.504 140.529 1.00 89.58  ? 675 TYR C C   1 
ATOM   14281 O O   . TYR C 1 675 ? 152.773 176.488 139.943 1.00 92.01  ? 675 TYR C O   1 
ATOM   14282 C CB  . TYR C 1 675 ? 153.955 173.942 141.640 1.00 86.22  ? 675 TYR C CB  1 
ATOM   14283 C CG  . TYR C 1 675 ? 154.833 172.702 141.638 1.00 88.03  ? 675 TYR C CG  1 
ATOM   14284 C CD1 . TYR C 1 675 ? 154.259 171.420 141.740 1.00 83.48  ? 675 TYR C CD1 1 
ATOM   14285 C CD2 . TYR C 1 675 ? 156.230 172.839 141.600 1.00 87.74  ? 675 TYR C CD2 1 
ATOM   14286 C CE1 . TYR C 1 675 ? 155.081 170.280 141.799 1.00 84.75  ? 675 TYR C CE1 1 
ATOM   14287 C CE2 . TYR C 1 675 ? 157.054 171.704 141.661 1.00 84.83  ? 675 TYR C CE2 1 
ATOM   14288 C CZ  . TYR C 1 675 ? 156.483 170.422 141.759 1.00 86.33  ? 675 TYR C CZ  1 
ATOM   14289 O OH  . TYR C 1 675 ? 157.299 169.340 141.817 1.00 86.61  ? 675 TYR C OH  1 
ATOM   14290 N N   . TRP C 1 676 ? 151.266 175.587 141.321 1.00 87.26  ? 676 TRP C N   1 
ATOM   14291 C CA  . TRP C 1 676 ? 150.457 176.807 141.479 1.00 84.73  ? 676 TRP C CA  1 
ATOM   14292 C C   . TRP C 1 676 ? 151.277 178.055 141.866 1.00 87.96  ? 676 TRP C C   1 
ATOM   14293 O O   . TRP C 1 676 ? 150.924 179.168 141.474 1.00 92.78  ? 676 TRP C O   1 
ATOM   14294 C CB  . TRP C 1 676 ? 149.359 176.520 142.512 1.00 84.47  ? 676 TRP C CB  1 
ATOM   14295 C CG  . TRP C 1 676 ? 149.817 176.255 143.916 1.00 90.74  ? 676 TRP C CG  1 
ATOM   14296 C CD1 . TRP C 1 676 ? 150.080 175.041 144.451 1.00 87.43  ? 676 TRP C CD1 1 
ATOM   14297 C CD2 . TRP C 1 676 ? 150.099 177.219 144.975 1.00 88.67  ? 676 TRP C CD2 1 
ATOM   14298 N NE1 . TRP C 1 676 ? 150.511 175.193 145.751 1.00 85.19  ? 676 TRP C NE1 1 
ATOM   14299 C CE2 . TRP C 1 676 ? 150.561 176.515 146.119 1.00 86.51  ? 676 TRP C CE2 1 
ATOM   14300 C CE3 . TRP C 1 676 ? 150.017 178.625 145.080 1.00 84.71  ? 676 TRP C CE3 1 
ATOM   14301 C CZ2 . TRP C 1 676 ? 150.949 177.166 147.296 1.00 85.81  ? 676 TRP C CZ2 1 
ATOM   14302 C CZ3 . TRP C 1 676 ? 150.403 179.290 146.257 1.00 87.19  ? 676 TRP C CZ3 1 
ATOM   14303 C CH2 . TRP C 1 676 ? 150.877 178.565 147.360 1.00 87.66  ? 676 TRP C CH2 1 
ATOM   14304 N N   . TRP C 1 677 ? 152.387 177.865 142.586 1.00 88.94  ? 677 TRP C N   1 
ATOM   14305 C CA  . TRP C 1 677 ? 153.345 178.878 143.050 1.00 90.93  ? 677 TRP C CA  1 
ATOM   14306 C C   . TRP C 1 677 ? 154.555 179.096 142.121 1.00 94.40  ? 677 TRP C C   1 
ATOM   14307 O O   . TRP C 1 677 ? 155.292 180.067 142.296 1.00 96.28  ? 677 TRP C O   1 
ATOM   14308 C CB  . TRP C 1 677 ? 153.835 178.430 144.434 1.00 88.68  ? 677 TRP C CB  1 
ATOM   14309 C CG  . TRP C 1 677 ? 154.566 177.119 144.467 1.00 85.07  ? 677 TRP C CG  1 
ATOM   14310 C CD1 . TRP C 1 677 ? 153.984 175.905 144.564 1.00 88.46  ? 677 TRP C CD1 1 
ATOM   14311 C CD2 . TRP C 1 677 ? 156.001 176.853 144.399 1.00 87.41  ? 677 TRP C CD2 1 
ATOM   14312 N NE1 . TRP C 1 677 ? 154.943 174.919 144.528 1.00 89.12  ? 677 TRP C NE1 1 
ATOM   14313 C CE2 . TRP C 1 677 ? 156.204 175.441 144.402 1.00 89.10  ? 677 TRP C CE2 1 
ATOM   14314 C CE3 . TRP C 1 677 ? 157.155 177.659 144.345 1.00 89.28  ? 677 TRP C CE3 1 
ATOM   14315 C CZ2 . TRP C 1 677 ? 157.472 174.856 144.304 1.00 88.06  ? 677 TRP C CZ2 1 
ATOM   14316 C CZ3 . TRP C 1 677 ? 158.438 177.084 144.249 1.00 92.34  ? 677 TRP C CZ3 1 
ATOM   14317 C CH2 . TRP C 1 677 ? 158.595 175.690 144.214 1.00 90.62  ? 677 TRP C CH2 1 
ATOM   14318 N N   . CYS C 1 678 ? 154.793 178.212 141.151 1.00 96.73  ? 678 CYS C N   1 
ATOM   14319 C CA  . CYS C 1 678 ? 155.966 178.204 140.269 1.00 96.26  ? 678 CYS C CA  1 
ATOM   14320 C C   . CYS C 1 678 ? 155.565 177.631 138.906 1.00 98.92  ? 678 CYS C C   1 
ATOM   14321 O O   . CYS C 1 678 ? 155.706 176.437 138.625 1.00 100.42 ? 678 CYS C O   1 
ATOM   14322 C CB  . CYS C 1 678 ? 157.108 177.426 140.931 1.00 99.90  ? 678 CYS C CB  1 
ATOM   14323 S SG  . CYS C 1 678 ? 158.568 177.361 139.851 1.00 101.59 ? 678 CYS C SG  1 
ATOM   14324 N N   . ARG C 1 679 ? 154.964 178.502 138.093 1.00 102.44 ? 679 ARG C N   1 
ATOM   14325 C CA  . ARG C 1 679 ? 154.308 178.154 136.828 1.00 99.87  ? 679 ARG C CA  1 
ATOM   14326 C C   . ARG C 1 679 ? 155.363 178.046 135.729 1.00 99.70  ? 679 ARG C C   1 
ATOM   14327 O O   . ARG C 1 679 ? 155.918 179.048 135.291 1.00 100.11 ? 679 ARG C O   1 
ATOM   14328 C CB  . ARG C 1 679 ? 153.181 179.163 136.536 1.00 98.28  ? 679 ARG C CB  1 
ATOM   14329 C CG  . ARG C 1 679 ? 152.123 179.111 137.657 1.00 99.48  ? 679 ARG C CG  1 
ATOM   14330 C CD  . ARG C 1 679 ? 151.045 180.190 137.551 1.00 101.77 ? 679 ARG C CD  1 
ATOM   14331 N NE  . ARG C 1 679 ? 150.327 180.318 138.835 1.00 106.47 ? 679 ARG C NE  1 
ATOM   14332 C CZ  . ARG C 1 679 ? 149.295 181.084 139.123 1.00 104.43 ? 679 ARG C CZ  1 
ATOM   14333 N NH1 . ARG C 1 679 ? 148.838 181.103 140.336 1.00 100.65 ? 679 ARG C NH1 1 
ATOM   14334 N NH2 . ARG C 1 679 ? 148.713 181.835 138.237 1.00 100.91 ? 679 ARG C NH2 1 
ATOM   14335 N N   . ARG C 1 680 ? 155.680 176.813 135.339 1.00 100.63 ? 680 ARG C N   1 
ATOM   14336 C CA  . ARG C 1 680 ? 156.800 176.415 134.469 1.00 96.87  ? 680 ARG C CA  1 
ATOM   14337 C C   . ARG C 1 680 ? 156.674 176.985 133.053 1.00 101.71 ? 680 ARG C C   1 
ATOM   14338 O O   . ARG C 1 680 ? 155.604 176.944 132.458 1.00 100.59 ? 680 ARG C O   1 
ATOM   14339 C CB  . ARG C 1 680 ? 156.839 174.876 134.488 1.00 98.04  ? 680 ARG C CB  1 
ATOM   14340 C CG  . ARG C 1 680 ? 157.783 174.180 133.507 1.00 98.38  ? 680 ARG C CG  1 
ATOM   14341 C CD  . ARG C 1 680 ? 157.731 172.663 133.752 1.00 102.05 ? 680 ARG C CD  1 
ATOM   14342 N NE  . ARG C 1 680 ? 158.181 171.893 132.574 1.00 102.50 ? 680 ARG C NE  1 
ATOM   14343 C CZ  . ARG C 1 680 ? 159.194 171.053 132.491 1.00 105.34 ? 680 ARG C CZ  1 
ATOM   14344 N NH1 . ARG C 1 680 ? 159.422 170.405 131.387 1.00 101.87 ? 680 ARG C NH1 1 
ATOM   14345 N NH2 . ARG C 1 680 ? 160.009 170.842 133.481 1.00 103.84 ? 680 ARG C NH2 1 
ATOM   14346 N N   . LYS C 1 681 ? 157.778 177.467 132.490 1.00 111.64 ? 681 LYS C N   1 
ATOM   14347 C CA  . LYS C 1 681 ? 157.864 177.853 131.080 1.00 109.83 ? 681 LYS C CA  1 
ATOM   14348 C C   . LYS C 1 681 ? 157.921 176.610 130.188 1.00 110.00 ? 681 LYS C C   1 
ATOM   14349 O O   . LYS C 1 681 ? 158.831 175.791 130.328 1.00 108.52 ? 681 LYS C O   1 
ATOM   14350 C CB  . LYS C 1 681 ? 159.108 178.712 130.877 1.00 104.08 ? 681 LYS C CB  1 
ATOM   14351 N N   . LYS C 1 682 ? 156.949 176.438 129.284 1.00 95.89  ? 682 LYS C N   1 
ATOM   14352 C CA  . LYS C 1 682 ? 156.825 175.230 128.452 1.00 97.99  ? 682 LYS C CA  1 
ATOM   14353 C C   . LYS C 1 682 ? 157.885 175.160 127.349 1.00 102.44 ? 682 LYS C C   1 
ATOM   14354 O O   . LYS C 1 682 ? 158.008 176.063 126.525 1.00 98.18  ? 682 LYS C O   1 
ATOM   14355 C CB  . LYS C 1 682 ? 155.413 175.125 127.855 1.00 97.43  ? 682 LYS C CB  1 
ATOM   14356 C CG  . LYS C 1 682 ? 154.359 174.788 128.918 1.00 99.21  ? 682 LYS C CG  1 
ATOM   14357 C CD  . LYS C 1 682 ? 152.988 174.644 128.258 1.00 99.55  ? 682 LYS C CD  1 
ATOM   14358 C CE  . LYS C 1 682 ? 151.914 174.264 129.274 1.00 97.65  ? 682 LYS C CE  1 
ATOM   14359 N NZ  . LYS C 1 682 ? 150.571 174.249 128.641 1.00 98.54  ? 682 LYS C NZ  1 
ATOM   14360 N N   . HIS C 1 683 ? 158.609 174.044 127.310 1.00 103.16 ? 683 HIS C N   1 
ATOM   14361 C CA  . HIS C 1 683 ? 159.478 173.625 126.204 1.00 99.60  ? 683 HIS C CA  1 
ATOM   14362 C C   . HIS C 1 683 ? 158.639 173.186 124.992 1.00 98.73  ? 683 HIS C C   1 
ATOM   14363 O O   . HIS C 1 683 ? 157.547 172.644 125.161 1.00 99.98  ? 683 HIS C O   1 
ATOM   14364 C CB  . HIS C 1 683 ? 160.397 172.510 126.735 1.00 99.52  ? 683 HIS C CB  1 
ATOM   14365 C CG  . HIS C 1 683 ? 161.205 171.789 125.690 1.00 106.44 ? 683 HIS C CG  1 
ATOM   14366 N ND1 . HIS C 1 683 ? 160.890 170.542 125.155 1.00 102.00 ? 683 HIS C ND1 1 
ATOM   14367 C CD2 . HIS C 1 683 ? 162.350 172.239 125.111 1.00 104.29 ? 683 HIS C CD2 1 
ATOM   14368 C CE1 . HIS C 1 683 ? 161.852 170.263 124.265 1.00 100.82 ? 683 HIS C CE1 1 
ATOM   14369 N NE2 . HIS C 1 683 ? 162.743 171.266 124.220 1.00 101.58 ? 683 HIS C NE2 1 
ATOM   14370 N N   . ARG C 1 684 ? 159.126 173.441 123.771 1.00 88.21  ? 684 ARG C N   1 
ATOM   14371 C CA  . ARG C 1 684 ? 158.434 173.151 122.505 1.00 86.65  ? 684 ARG C CA  1 
ATOM   14372 C C   . ARG C 1 684 ? 159.014 171.906 121.842 1.00 88.38  ? 684 ARG C C   1 
ATOM   14373 O O   . ARG C 1 684 ? 160.227 171.807 121.670 1.00 88.88  ? 684 ARG C O   1 
ATOM   14374 C CB  . ARG C 1 684 ? 158.528 174.382 121.596 1.00 86.07  ? 684 ARG C CB  1 
ATOM   14375 C CG  . ARG C 1 684 ? 157.566 174.298 120.412 1.00 81.98  ? 684 ARG C CG  1 
ATOM   14376 C CD  . ARG C 1 684 ? 157.579 175.608 119.628 1.00 81.18  ? 684 ARG C CD  1 
ATOM   14377 N NE  . ARG C 1 684 ? 156.500 175.640 118.631 1.00 88.79  ? 684 ARG C NE  1 
ATOM   14378 C CZ  . ARG C 1 684 ? 156.169 176.654 117.859 1.00 91.31  ? 684 ARG C CZ  1 
ATOM   14379 N NH1 . ARG C 1 684 ? 155.151 176.567 117.058 1.00 87.79  ? 684 ARG C NH1 1 
ATOM   14380 N NH2 . ARG C 1 684 ? 156.835 177.771 117.864 1.00 90.97  ? 684 ARG C NH2 1 
ATOM   14381 N N   . GLU C 1 685 ? 158.171 170.942 121.505 1.00 88.14  ? 685 GLU C N   1 
ATOM   14382 C CA  . GLU C 1 685 ? 158.594 169.634 120.994 1.00 88.68  ? 685 GLU C CA  1 
ATOM   14383 C C   . GLU C 1 685 ? 158.892 169.661 119.485 1.00 89.96  ? 685 GLU C C   1 
ATOM   14384 O O   . GLU C 1 685 ? 158.355 170.476 118.738 1.00 93.14  ? 685 GLU C O   1 
ATOM   14385 C CB  . GLU C 1 685 ? 157.531 168.569 121.288 1.00 88.72  ? 685 GLU C CB  1 
ATOM   14386 C CG  . GLU C 1 685 ? 156.998 168.539 122.728 1.00 89.74  ? 685 GLU C CG  1 
ATOM   14387 C CD  . GLU C 1 685 ? 157.973 168.061 123.805 1.00 91.04  ? 685 GLU C CD  1 
ATOM   14388 O OE1 . GLU C 1 685 ? 159.045 167.514 123.481 1.00 94.70  ? 685 GLU C OE1 1 
ATOM   14389 O OE2 . GLU C 1 685 ? 157.607 168.203 124.990 1.00 93.44  ? 685 GLU C OE2 1 
ATOM   14390 N N   . GLY C 1 686 ? 159.724 168.738 119.008 1.00 80.42  ? 686 GLY C N   1 
ATOM   14391 C CA  . GLY C 1 686 ? 160.137 168.694 117.607 1.00 80.34  ? 686 GLY C CA  1 
ATOM   14392 C C   . GLY C 1 686 ? 161.146 169.779 117.226 1.00 82.16  ? 686 GLY C C   1 
ATOM   14393 O O   . GLY C 1 686 ? 161.734 170.437 118.082 1.00 81.79  ? 686 GLY C O   1 
ATOM   14394 N N   . ARG C 1 687 ? 161.377 169.944 115.924 1.00 93.46  ? 687 ARG C N   1 
ATOM   14395 C CA  . ARG C 1 687 ? 162.321 170.893 115.318 1.00 91.04  ? 687 ARG C CA  1 
ATOM   14396 C C   . ARG C 1 687 ? 161.633 171.688 114.222 1.00 89.37  ? 687 ARG C C   1 
ATOM   14397 O O   . ARG C 1 687 ? 160.813 171.138 113.497 1.00 91.72  ? 687 ARG C O   1 
ATOM   14398 C CB  . ARG C 1 687 ? 163.519 170.149 114.710 1.00 93.14  ? 687 ARG C CB  1 
ATOM   14399 C CG  . ARG C 1 687 ? 164.365 169.380 115.723 1.00 96.82  ? 687 ARG C CG  1 
ATOM   14400 C CD  . ARG C 1 687 ? 165.591 168.780 115.036 1.00 95.84  ? 687 ARG C CD  1 
ATOM   14401 N NE  . ARG C 1 687 ? 166.394 167.964 115.961 1.00 101.36 ? 687 ARG C NE  1 
ATOM   14402 C CZ  . ARG C 1 687 ? 167.632 167.546 115.776 1.00 100.53 ? 687 ARG C CZ  1 
ATOM   14403 N NH1 . ARG C 1 687 ? 168.231 166.832 116.680 1.00 93.59  ? 687 ARG C NH1 1 
ATOM   14404 N NH2 . ARG C 1 687 ? 168.297 167.818 114.696 1.00 97.20  ? 687 ARG C NH2 1 
ATOM   14405 N N   . LEU C 1 688 ? 162.003 172.948 114.041 1.00 84.03  ? 688 LEU C N   1 
ATOM   14406 C CA  . LEU C 1 688 ? 161.577 173.731 112.882 1.00 88.31  ? 688 LEU C CA  1 
ATOM   14407 C C   . LEU C 1 688 ? 162.311 173.248 111.623 1.00 90.97  ? 688 LEU C C   1 
ATOM   14408 O O   . LEU C 1 688 ? 163.503 173.501 111.473 1.00 95.43  ? 688 LEU C O   1 
ATOM   14409 C CB  . LEU C 1 688 ? 161.812 175.220 113.175 1.00 92.33  ? 688 LEU C CB  1 
ATOM   14410 C CG  . LEU C 1 688 ? 161.403 176.175 112.045 1.00 93.29  ? 688 LEU C CG  1 
ATOM   14411 C CD1 . LEU C 1 688 ? 159.937 176.038 111.670 1.00 93.90  ? 688 LEU C CD1 1 
ATOM   14412 C CD2 . LEU C 1 688 ? 161.638 177.612 112.484 1.00 93.30  ? 688 LEU C CD2 1 
ATOM   14413 N N   . LEU C 1 689 ? 161.614 172.558 110.724 1.00 96.65  ? 689 LEU C N   1 
ATOM   14414 C CA  . LEU C 1 689 ? 162.181 171.953 109.518 1.00 97.36  ? 689 LEU C CA  1 
ATOM   14415 C C   . LEU C 1 689 ? 161.435 172.407 108.265 1.00 98.52  ? 689 LEU C C   1 
ATOM   14416 O O   . LEU C 1 689 ? 160.208 172.496 108.262 1.00 102.84 ? 689 LEU C O   1 
ATOM   14417 C CB  . LEU C 1 689 ? 162.145 170.418 109.635 1.00 96.65  ? 689 LEU C CB  1 
ATOM   14418 C CG  . LEU C 1 689 ? 163.002 169.824 110.763 1.00 100.75 ? 689 LEU C CG  1 
ATOM   14419 C CD1 . LEU C 1 689 ? 162.801 168.319 110.833 1.00 95.11  ? 689 LEU C CD1 1 
ATOM   14420 C CD2 . LEU C 1 689 ? 164.491 170.076 110.558 1.00 99.22  ? 689 LEU C CD2 1 
ATOM   14421 N N   . LYS C 1 690 ? 162.173 172.654 107.178 1.00 107.96 ? 690 LYS C N   1 
ATOM   14422 C CA  . LYS C 1 690 ? 161.609 172.846 105.834 1.00 111.69 ? 690 LYS C CA  1 
ATOM   14423 C C   . LYS C 1 690 ? 161.133 171.503 105.280 1.00 109.89 ? 690 LYS C C   1 
ATOM   14424 O O   . LYS C 1 690 ? 161.946 170.614 105.036 1.00 107.45 ? 690 LYS C O   1 
ATOM   14425 C CB  . LYS C 1 690 ? 162.657 173.504 104.920 1.00 109.95 ? 690 LYS C CB  1 
ATOM   14426 C CG  . LYS C 1 690 ? 162.113 173.764 103.509 1.00 109.58 ? 690 LYS C CG  1 
ATOM   14427 C CD  . LYS C 1 690 ? 163.149 174.483 102.643 1.00 108.92 ? 690 LYS C CD  1 
ATOM   14428 C CE  . LYS C 1 690 ? 162.690 174.523 101.188 1.00 109.69 ? 690 LYS C CE  1 
ATOM   14429 N NZ  . LYS C 1 690 ? 163.667 175.206 100.316 1.00 108.72 ? 690 LYS C NZ  1 
ATOM   14430 N N   . VAL C 1 691 ? 159.830 171.363 105.064 1.00 101.04 ? 691 VAL C N   1 
ATOM   14431 C CA  . VAL C 1 691 ? 159.219 170.159 104.463 1.00 102.30 ? 691 VAL C CA  1 
ATOM   14432 C C   . VAL C 1 691 ? 158.942 170.316 102.962 1.00 104.14 ? 691 VAL C C   1 
ATOM   14433 O O   . VAL C 1 691 ? 158.772 169.320 102.261 1.00 100.50 ? 691 VAL C O   1 
ATOM   14434 C CB  . VAL C 1 691 ? 157.960 169.727 105.237 1.00 97.93  ? 691 VAL C CB  1 
ATOM   14435 C CG1 . VAL C 1 691 ? 158.328 169.231 106.633 1.00 93.64  ? 691 VAL C CG1 1 
ATOM   14436 C CG2 . VAL C 1 691 ? 156.916 170.827 105.374 1.00 97.34  ? 691 VAL C CG2 1 
ATOM   14437 N N   . GLY C 1 692 ? 158.941 171.548 102.448 1.00 116.75 ? 692 GLY C N   1 
ATOM   14438 C CA  . GLY C 1 692 ? 158.692 171.858 101.040 1.00 115.94 ? 692 GLY C CA  1 
ATOM   14439 C C   . GLY C 1 692 ? 158.562 173.361 100.773 1.00 120.33 ? 692 GLY C C   1 
ATOM   14440 O O   . GLY C 1 692 ? 159.100 174.183 101.519 1.00 120.43 ? 692 GLY C O   1 
ATOM   14441 N N   . THR C 1 693 ? 157.834 173.728 99.713  1.00 132.06 ? 693 THR C N   1 
ATOM   14442 C CA  . THR C 1 693 ? 157.525 175.124 99.335  1.00 132.63 ? 693 THR C CA  1 
ATOM   14443 C C   . THR C 1 693 ? 156.037 175.433 99.553  1.00 130.69 ? 693 THR C C   1 
ATOM   14444 O O   . THR C 1 693 ? 155.172 174.675 99.112  1.00 129.54 ? 693 THR C O   1 
ATOM   14445 C CB  . THR C 1 693 ? 157.946 175.406 97.883  1.00 130.11 ? 693 THR C CB  1 
ATOM   14446 O OG1 . THR C 1 693 ? 159.313 175.097 97.721  1.00 128.04 ? 693 THR C OG1 1 
ATOM   14447 C CG2 . THR C 1 693 ? 157.779 176.872 97.492  1.00 127.99 ? 693 THR C CG2 1 
ATOM   14448 N N   . ARG C 1 694 ? 155.720 176.532 100.254 1.00 133.79 ? 694 ARG C N   1 
ATOM   14449 C CA  . ARG C 1 694 ? 154.358 176.871 100.708 1.00 133.33 ? 694 ARG C CA  1 
ATOM   14450 C C   . ARG C 1 694 ? 153.475 177.404 99.571  1.00 132.70 ? 694 ARG C C   1 
ATOM   14451 O O   . ARG C 1 694 ? 153.759 178.460 99.005  1.00 131.37 ? 694 ARG C O   1 
ATOM   14452 C CB  . ARG C 1 694 ? 154.449 177.840 101.902 1.00 132.78 ? 694 ARG C CB  1 
ATOM   14453 C CG  . ARG C 1 694 ? 153.155 177.842 102.728 1.00 132.47 ? 694 ARG C CG  1 
ATOM   14454 C CD  . ARG C 1 694 ? 153.296 178.772 103.939 1.00 132.41 ? 694 ARG C CD  1 
ATOM   14455 N NE  . ARG C 1 694 ? 152.174 178.618 104.884 1.00 135.36 ? 694 ARG C NE  1 
ATOM   14456 C CZ  . ARG C 1 694 ? 151.940 179.348 105.960 1.00 135.14 ? 694 ARG C CZ  1 
ATOM   14457 N NH1 . ARG C 1 694 ? 150.966 179.052 106.767 1.00 132.21 ? 694 ARG C NH1 1 
ATOM   14458 N NH2 . ARG C 1 694 ? 152.664 180.387 106.263 1.00 135.32 ? 694 ARG C NH2 1 
ATOM   14459 N N   . PRO C 1 699 ? 159.451 179.505 102.665 1.00 127.01 ? 699 PRO C N   1 
ATOM   14460 C CA  . PRO C 1 699 ? 159.104 178.124 102.366 1.00 128.10 ? 699 PRO C CA  1 
ATOM   14461 C C   . PRO C 1 699 ? 158.075 177.518 103.331 1.00 129.27 ? 699 PRO C C   1 
ATOM   14462 O O   . PRO C 1 699 ? 157.542 178.186 104.216 1.00 125.77 ? 699 PRO C O   1 
ATOM   14463 C CB  . PRO C 1 699 ? 160.433 177.366 102.381 1.00 125.10 ? 699 PRO C CB  1 
ATOM   14464 C CG  . PRO C 1 699 ? 161.458 178.435 102.036 1.00 125.90 ? 699 PRO C CG  1 
ATOM   14465 C CD  . PRO C 1 699 ? 160.884 179.681 102.695 1.00 125.87 ? 699 PRO C CD  1 
ATOM   14466 N N   . ASP C 1 700 ? 157.771 176.231 103.154 1.00 121.72 ? 700 ASP C N   1 
ATOM   14467 C CA  . ASP C 1 700 ? 156.922 175.472 104.072 1.00 120.33 ? 700 ASP C CA  1 
ATOM   14468 C C   . ASP C 1 700 ? 157.784 174.937 105.220 1.00 115.88 ? 700 ASP C C   1 
ATOM   14469 O O   . ASP C 1 700 ? 158.332 173.838 105.154 1.00 111.97 ? 700 ASP C O   1 
ATOM   14470 C CB  . ASP C 1 700 ? 156.181 174.370 103.297 1.00 119.14 ? 700 ASP C CB  1 
ATOM   14471 C CG  . ASP C 1 700 ? 155.017 173.747 104.067 1.00 121.12 ? 700 ASP C CG  1 
ATOM   14472 O OD1 . ASP C 1 700 ? 154.725 174.155 105.209 1.00 119.32 ? 700 ASP C OD1 1 
ATOM   14473 O OD2 . ASP C 1 700 ? 154.352 172.845 103.513 1.00 119.03 ? 700 ASP C OD2 1 
ATOM   14474 N N   . GLU C 1 701 ? 157.977 175.763 106.248 1.00 106.86 ? 701 GLU C N   1 
ATOM   14475 C CA  . GLU C 1 701 ? 158.768 175.444 107.436 1.00 108.21 ? 701 GLU C CA  1 
ATOM   14476 C C   . GLU C 1 701 ? 157.840 175.222 108.630 1.00 108.03 ? 701 GLU C C   1 
ATOM   14477 O O   . GLU C 1 701 ? 157.012 176.078 108.951 1.00 107.92 ? 701 GLU C O   1 
ATOM   14478 C CB  . GLU C 1 701 ? 159.793 176.550 107.731 1.00 109.74 ? 701 GLU C CB  1 
ATOM   14479 C CG  . GLU C 1 701 ? 160.817 176.701 106.599 1.00 112.17 ? 701 GLU C CG  1 
ATOM   14480 C CD  . GLU C 1 701 ? 161.887 177.767 106.883 1.00 112.78 ? 701 GLU C CD  1 
ATOM   14481 O OE1 . GLU C 1 701 ? 161.576 178.815 107.492 1.00 111.07 ? 701 GLU C OE1 1 
ATOM   14482 O OE2 . GLU C 1 701 ? 163.053 177.570 106.476 1.00 110.37 ? 701 GLU C OE2 1 
ATOM   14483 N N   . ARG C 1 702 ? 157.974 174.035 109.257 1.00 90.58  ? 702 ARG C N   1 
ATOM   14484 C CA  . ARG C 1 702 ? 157.035 173.623 110.339 1.00 85.40  ? 702 ARG C CA  1 
ATOM   14485 C C   . ARG C 1 702 ? 157.709 172.913 111.500 1.00 88.29  ? 702 ARG C C   1 
ATOM   14486 O O   . ARG C 1 702 ? 158.720 172.218 111.273 1.00 93.38  ? 702 ARG C O   1 
ATOM   14487 C CB  . ARG C 1 702 ? 156.083 172.565 109.778 1.00 82.94  ? 702 ARG C CB  1 
ATOM   14488 C CG  . ARG C 1 702 ? 155.353 172.990 108.510 1.00 83.69  ? 702 ARG C CG  1 
ATOM   14489 C CD  . ARG C 1 702 ? 154.238 171.992 108.249 1.00 87.72  ? 702 ARG C CD  1 
ATOM   14490 N NE  . ARG C 1 702 ? 153.691 172.168 106.910 1.00 89.74  ? 702 ARG C NE  1 
ATOM   14491 C CZ  . ARG C 1 702 ? 152.777 171.376 106.361 1.00 88.69  ? 702 ARG C CZ  1 
ATOM   14492 N NH1 . ARG C 1 702 ? 152.344 171.615 105.136 1.00 85.82  ? 702 ARG C NH1 1 
ATOM   14493 N NH2 . ARG C 1 702 ? 152.302 170.346 107.038 1.00 88.56  ? 702 ARG C NH2 1 
ATOM   14494 N N   . TRP C 1 703 ? 157.156 173.088 112.696 1.00 86.67  ? 703 TRP C N   1 
ATOM   14495 C CA  . TRP C 1 703 ? 157.602 172.329 113.858 1.00 87.08  ? 703 TRP C CA  1 
ATOM   14496 C C   . TRP C 1 703 ? 157.199 170.867 113.702 1.00 85.76  ? 703 TRP C C   1 
ATOM   14497 O O   . TRP C 1 703 ? 156.083 170.464 114.014 1.00 88.00  ? 703 TRP C O   1 
ATOM   14498 C CB  . TRP C 1 703 ? 157.096 172.996 115.130 1.00 81.52  ? 703 TRP C CB  1 
ATOM   14499 C CG  . TRP C 1 703 ? 157.880 174.230 115.432 1.00 83.41  ? 703 TRP C CG  1 
ATOM   14500 C CD1 . TRP C 1 703 ? 157.714 175.433 114.844 1.00 85.01  ? 703 TRP C CD1 1 
ATOM   14501 C CD2 . TRP C 1 703 ? 159.050 174.363 116.290 1.00 87.89  ? 703 TRP C CD2 1 
ATOM   14502 N NE1 . TRP C 1 703 ? 158.690 176.299 115.286 1.00 86.51  ? 703 TRP C NE1 1 
ATOM   14503 C CE2 . TRP C 1 703 ? 159.538 175.696 116.183 1.00 90.88  ? 703 TRP C CE2 1 
ATOM   14504 C CE3 . TRP C 1 703 ? 159.743 173.496 117.158 1.00 86.95  ? 703 TRP C CE3 1 
ATOM   14505 C CZ2 . TRP C 1 703 ? 160.657 176.145 116.895 1.00 89.93  ? 703 TRP C CZ2 1 
ATOM   14506 C CZ3 . TRP C 1 703 ? 160.854 173.943 117.893 1.00 88.19  ? 703 TRP C CZ3 1 
ATOM   14507 C CH2 . TRP C 1 703 ? 161.314 175.262 117.765 1.00 87.74  ? 703 TRP C CH2 1 
ATOM   14508 N N   . CYS C 1 704 ? 158.126 170.093 113.151 1.00 77.20  ? 704 CYS C N   1 
ATOM   14509 C CA  . CYS C 1 704 ? 157.990 168.681 112.851 1.00 71.57  ? 704 CYS C CA  1 
ATOM   14510 C C   . CYS C 1 704 ? 158.617 167.814 113.936 1.00 75.70  ? 704 CYS C C   1 
ATOM   14511 O O   . CYS C 1 704 ? 159.637 168.164 114.520 1.00 81.00  ? 704 CYS C O   1 
ATOM   14512 C CB  . CYS C 1 704 ? 158.667 168.383 111.516 1.00 83.40  ? 704 CYS C CB  1 
ATOM   14513 S SG  . CYS C 1 704 ? 157.602 168.884 110.154 1.00 95.63  ? 704 CYS C SG  1 
ATOM   14514 N N   . PHE C 1 705 ? 158.036 166.649 114.168 1.00 63.22  ? 705 PHE C N   1 
ATOM   14515 C CA  . PHE C 1 705 ? 158.498 165.666 115.129 1.00 61.68  ? 705 PHE C CA  1 
ATOM   14516 C C   . PHE C 1 705 ? 158.744 164.323 114.450 1.00 61.21  ? 705 PHE C C   1 
ATOM   14517 O O   . PHE C 1 705 ? 157.845 163.765 113.831 1.00 66.91  ? 705 PHE C O   1 
ATOM   14518 C CB  . PHE C 1 705 ? 157.441 165.623 116.221 1.00 68.31  ? 705 PHE C CB  1 
ATOM   14519 C CG  . PHE C 1 705 ? 157.596 164.542 117.253 1.00 66.77  ? 705 PHE C CG  1 
ATOM   14520 C CD1 . PHE C 1 705 ? 158.447 164.731 118.355 1.00 59.21  ? 705 PHE C CD1 1 
ATOM   14521 C CD2 . PHE C 1 705 ? 156.846 163.365 117.126 1.00 64.46  ? 705 PHE C CD2 1 
ATOM   14522 C CE1 . PHE C 1 705 ? 158.556 163.730 119.329 1.00 56.09  ? 705 PHE C CE1 1 
ATOM   14523 C CE2 . PHE C 1 705 ? 156.943 162.375 118.107 1.00 69.75  ? 705 PHE C CE2 1 
ATOM   14524 C CZ  . PHE C 1 705 ? 157.804 162.557 119.201 1.00 68.11  ? 705 PHE C CZ  1 
ATOM   14525 N N   . ARG C 1 706 ? 159.984 163.823 114.575 1.00 67.78  ? 706 ARG C N   1 
ATOM   14526 C CA  . ARG C 1 706 ? 160.414 162.591 113.854 1.00 67.96  ? 706 ARG C CA  1 
ATOM   14527 C C   . ARG C 1 706 ? 160.043 161.308 114.591 1.00 65.84  ? 706 ARG C C   1 
ATOM   14528 O O   . ARG C 1 706 ? 160.500 161.127 115.737 1.00 76.65  ? 706 ARG C O   1 
ATOM   14529 C CB  . ARG C 1 706 ? 161.933 162.653 113.662 1.00 67.24  ? 706 ARG C CB  1 
ATOM   14530 C CG  . ARG C 1 706 ? 162.467 161.468 112.851 1.00 69.10  ? 706 ARG C CG  1 
ATOM   14531 C CD  . ARG C 1 706 ? 163.977 161.582 112.631 1.00 70.91  ? 706 ARG C CD  1 
ATOM   14532 N NE  . ARG C 1 706 ? 164.299 162.620 111.640 1.00 74.10  ? 706 ARG C NE  1 
ATOM   14533 C CZ  . ARG C 1 706 ? 164.452 163.909 111.921 1.00 77.43  ? 706 ARG C CZ  1 
ATOM   14534 N NH1 . ARG C 1 706 ? 164.740 164.767 110.956 1.00 71.10  ? 706 ARG C NH1 1 
ATOM   14535 N NH2 . ARG C 1 706 ? 164.312 164.337 113.163 1.00 79.03  ? 706 ARG C NH2 1 
ATOM   14536 N N   . VAL C 1 707 ? 159.249 160.464 113.952 1.00 61.83  ? 707 VAL C N   1 
ATOM   14537 C CA  . VAL C 1 707 ? 158.857 159.135 114.436 1.00 64.70  ? 707 VAL C CA  1 
ATOM   14538 C C   . VAL C 1 707 ? 159.509 158.085 113.546 1.00 72.48  ? 707 VAL C C   1 
ATOM   14539 O O   . VAL C 1 707 ? 159.534 158.235 112.330 1.00 81.04  ? 707 VAL C O   1 
ATOM   14540 C CB  . VAL C 1 707 ? 157.331 158.977 114.441 1.00 71.93  ? 707 VAL C CB  1 
ATOM   14541 C CG1 . VAL C 1 707 ? 156.873 157.603 114.932 1.00 69.30  ? 707 VAL C CG1 1 
ATOM   14542 C CG2 . VAL C 1 707 ? 156.641 160.027 115.315 1.00 77.18  ? 707 VAL C CG2 1 
ATOM   14543 N N   . GLU C 1 708 ? 160.042 157.020 114.135 1.00 80.50  ? 708 GLU C N   1 
ATOM   14544 C CA  . GLU C 1 708 ? 160.619 155.883 113.416 1.00 72.25  ? 708 GLU C CA  1 
ATOM   14545 C C   . GLU C 1 708 ? 159.763 154.642 113.688 1.00 73.75  ? 708 GLU C C   1 
ATOM   14546 O O   . GLU C 1 708 ? 159.643 154.209 114.829 1.00 78.33  ? 708 GLU C O   1 
ATOM   14547 C CB  . GLU C 1 708 ? 162.069 155.659 113.858 1.00 71.20  ? 708 GLU C CB  1 
ATOM   14548 C CG  . GLU C 1 708 ? 162.937 156.930 113.864 1.00 76.59  ? 708 GLU C CG  1 
ATOM   14549 C CD  . GLU C 1 708 ? 164.354 156.686 114.397 1.00 87.34  ? 708 GLU C CD  1 
ATOM   14550 O OE1 . GLU C 1 708 ? 164.546 155.789 115.250 1.00 90.26  ? 708 GLU C OE1 1 
ATOM   14551 O OE2 . GLU C 1 708 ? 165.274 157.433 113.999 1.00 85.77  ? 708 GLU C OE2 1 
ATOM   14552 N N   . GLU C 1 709 ? 159.147 154.072 112.659 1.00 87.74  ? 709 GLU C N   1 
ATOM   14553 C CA  . GLU C 1 709 ? 158.310 152.876 112.761 1.00 91.73  ? 709 GLU C CA  1 
ATOM   14554 C C   . GLU C 1 709 ? 159.032 151.683 112.140 1.00 96.11  ? 709 GLU C C   1 
ATOM   14555 O O   . GLU C 1 709 ? 159.422 151.743 110.977 1.00 99.11  ? 709 GLU C O   1 
ATOM   14556 C CB  . GLU C 1 709 ? 156.957 153.121 112.067 1.00 89.53  ? 709 GLU C CB  1 
ATOM   14557 C CG  . GLU C 1 709 ? 156.056 151.873 112.075 1.00 90.00  ? 709 GLU C CG  1 
ATOM   14558 C CD  . GLU C 1 709 ? 154.749 152.005 111.274 1.00 100.24 ? 709 GLU C CD  1 
ATOM   14559 O OE1 . GLU C 1 709 ? 154.494 153.060 110.652 1.00 100.62 ? 709 GLU C OE1 1 
ATOM   14560 O OE2 . GLU C 1 709 ? 153.968 151.026 111.263 1.00 100.48 ? 709 GLU C OE2 1 
ATOM   14561 N N   . VAL C 1 710 ? 159.155 150.580 112.879 1.00 87.97  ? 710 VAL C N   1 
ATOM   14562 C CA  . VAL C 1 710 ? 159.580 149.281 112.350 1.00 83.93  ? 710 VAL C CA  1 
ATOM   14563 C C   . VAL C 1 710 ? 158.364 148.367 112.306 1.00 85.74  ? 710 VAL C C   1 
ATOM   14564 O O   . VAL C 1 710 ? 157.721 148.148 113.331 1.00 84.32  ? 710 VAL C O   1 
ATOM   14565 C CB  . VAL C 1 710 ? 160.686 148.656 113.210 1.00 83.01  ? 710 VAL C CB  1 
ATOM   14566 C CG1 . VAL C 1 710 ? 161.204 147.371 112.563 1.00 85.34  ? 710 VAL C CG1 1 
ATOM   14567 C CG2 . VAL C 1 710 ? 161.863 149.609 113.422 1.00 83.87  ? 710 VAL C CG2 1 
ATOM   14568 N N   . ASN C 1 711 ? 158.025 147.826 111.136 1.00 87.87  ? 711 ASN C N   1 
ATOM   14569 C CA  . ASN C 1 711 ? 156.800 147.048 110.958 1.00 84.19  ? 711 ASN C CA  1 
ATOM   14570 C C   . ASN C 1 711 ? 156.973 145.953 109.895 1.00 87.58  ? 711 ASN C C   1 
ATOM   14571 O O   . ASN C 1 711 ? 156.551 146.091 108.749 1.00 91.60  ? 711 ASN C O   1 
ATOM   14572 C CB  . ASN C 1 711 ? 155.660 148.032 110.656 1.00 86.19  ? 711 ASN C CB  1 
ATOM   14573 C CG  . ASN C 1 711 ? 154.279 147.426 110.796 1.00 85.84  ? 711 ASN C CG  1 
ATOM   14574 O OD1 . ASN C 1 711 ? 154.076 146.223 110.714 1.00 82.47  ? 711 ASN C OD1 1 
ATOM   14575 N ND2 . ASN C 1 711 ? 153.289 148.249 111.033 1.00 86.59  ? 711 ASN C ND2 1 
ATOM   14576 N N   . TRP C 1 712 ? 157.600 144.841 110.282 1.00 86.47  ? 712 TRP C N   1 
ATOM   14577 C CA  . TRP C 1 712 ? 157.777 143.670 109.425 1.00 86.45  ? 712 TRP C CA  1 
ATOM   14578 C C   . TRP C 1 712 ? 156.444 143.116 108.919 1.00 86.82  ? 712 TRP C C   1 
ATOM   14579 O O   . TRP C 1 712 ? 156.297 142.876 107.726 1.00 85.16  ? 712 TRP C O   1 
ATOM   14580 C CB  . TRP C 1 712 ? 158.523 142.583 110.201 1.00 85.35  ? 712 TRP C CB  1 
ATOM   14581 C CG  . TRP C 1 712 ? 159.993 142.780 110.376 1.00 87.86  ? 712 TRP C CG  1 
ATOM   14582 C CD1 . TRP C 1 712 ? 160.594 143.502 111.348 1.00 85.41  ? 712 TRP C CD1 1 
ATOM   14583 C CD2 . TRP C 1 712 ? 161.072 142.205 109.580 1.00 88.43  ? 712 TRP C CD2 1 
ATOM   14584 N NE1 . TRP C 1 712 ? 161.964 143.421 111.201 1.00 88.31  ? 712 TRP C NE1 1 
ATOM   14585 C CE2 . TRP C 1 712 ? 162.314 142.612 110.144 1.00 90.52  ? 712 TRP C CE2 1 
ATOM   14586 C CE3 . TRP C 1 712 ? 161.121 141.346 108.466 1.00 81.59  ? 712 TRP C CE3 1 
ATOM   14587 C CZ2 . TRP C 1 712 ? 163.544 142.188 109.623 1.00 84.27  ? 712 TRP C CZ2 1 
ATOM   14588 C CZ3 . TRP C 1 712 ? 162.351 140.923 107.932 1.00 83.54  ? 712 TRP C CZ3 1 
ATOM   14589 C CH2 . TRP C 1 712 ? 163.559 141.338 108.508 1.00 83.24  ? 712 TRP C CH2 1 
ATOM   14590 N N   . ALA C 1 713 ? 155.455 142.958 109.799 1.00 94.42  ? 713 ALA C N   1 
ATOM   14591 C CA  . ALA C 1 713 ? 154.170 142.359 109.448 1.00 91.36  ? 713 ALA C CA  1 
ATOM   14592 C C   . ALA C 1 713 ? 153.430 143.129 108.339 1.00 92.22  ? 713 ALA C C   1 
ATOM   14593 O O   . ALA C 1 713 ? 152.874 142.507 107.438 1.00 92.30  ? 713 ALA C O   1 
ATOM   14594 C CB  . ALA C 1 713 ? 153.331 142.257 110.725 1.00 85.85  ? 713 ALA C CB  1 
ATOM   14595 N N   . ALA C 1 714 ? 153.447 144.467 108.361 1.00 90.05  ? 714 ALA C N   1 
ATOM   14596 C CA  . ALA C 1 714 ? 152.874 145.278 107.288 1.00 87.12  ? 714 ALA C CA  1 
ATOM   14597 C C   . ALA C 1 714 ? 153.773 145.326 106.045 1.00 88.26  ? 714 ALA C C   1 
ATOM   14598 O O   . ALA C 1 714 ? 153.278 145.261 104.926 1.00 90.67  ? 714 ALA C O   1 
ATOM   14599 C CB  . ALA C 1 714 ? 152.610 146.688 107.817 1.00 84.78  ? 714 ALA C CB  1 
ATOM   14600 N N   . TRP C 1 715 ? 155.090 145.422 106.217 1.00 84.17  ? 715 TRP C N   1 
ATOM   14601 C CA  . TRP C 1 715 ? 156.041 145.530 105.107 1.00 84.69  ? 715 TRP C CA  1 
ATOM   14602 C C   . TRP C 1 715 ? 156.105 144.273 104.247 1.00 88.46  ? 715 TRP C C   1 
ATOM   14603 O O   . TRP C 1 715 ? 156.079 144.374 103.022 1.00 89.67  ? 715 TRP C O   1 
ATOM   14604 C CB  . TRP C 1 715 ? 157.420 145.872 105.662 1.00 81.95  ? 715 TRP C CB  1 
ATOM   14605 C CG  . TRP C 1 715 ? 158.548 145.770 104.691 1.00 83.22  ? 715 TRP C CG  1 
ATOM   14606 C CD1 . TRP C 1 715 ? 158.768 146.593 103.643 1.00 81.89  ? 715 TRP C CD1 1 
ATOM   14607 C CD2 . TRP C 1 715 ? 159.616 144.785 104.656 1.00 88.24  ? 715 TRP C CD2 1 
ATOM   14608 N NE1 . TRP C 1 715 ? 159.917 146.206 102.989 1.00 80.87  ? 715 TRP C NE1 1 
ATOM   14609 C CE2 . TRP C 1 715 ? 160.508 145.123 103.601 1.00 86.35  ? 715 TRP C CE2 1 
ATOM   14610 C CE3 . TRP C 1 715 ? 159.937 143.655 105.434 1.00 81.81  ? 715 TRP C CE3 1 
ATOM   14611 C CZ2 . TRP C 1 715 ? 161.681 144.407 103.353 1.00 76.99  ? 715 TRP C CZ2 1 
ATOM   14612 C CZ3 . TRP C 1 715 ? 161.101 142.915 105.178 1.00 78.21  ? 715 TRP C CZ3 1 
ATOM   14613 C CH2 . TRP C 1 715 ? 161.981 143.296 104.158 1.00 76.26  ? 715 TRP C CH2 1 
ATOM   14614 N N   . GLU C 1 716 ? 156.120 143.083 104.843 1.00 100.43 ? 716 GLU C N   1 
ATOM   14615 C CA  . GLU C 1 716 ? 156.229 141.827 104.100 1.00 96.93  ? 716 GLU C CA  1 
ATOM   14616 C C   . GLU C 1 716 ? 155.071 141.596 103.122 1.00 99.64  ? 716 GLU C C   1 
ATOM   14617 O O   . GLU C 1 716 ? 155.253 140.989 102.070 1.00 99.53  ? 716 GLU C O   1 
ATOM   14618 C CB  . GLU C 1 716 ? 156.322 140.652 105.068 1.00 99.73  ? 716 GLU C CB  1 
ATOM   14619 C CG  . GLU C 1 716 ? 157.711 140.584 105.699 1.00 104.20 ? 716 GLU C CG  1 
ATOM   14620 C CD  . GLU C 1 716 ? 157.857 139.275 106.468 1.00 106.26 ? 716 GLU C CD  1 
ATOM   14621 O OE1 . GLU C 1 716 ? 157.401 139.187 107.624 1.00 103.79 ? 716 GLU C OE1 1 
ATOM   14622 O OE2 . GLU C 1 716 ? 158.407 138.315 105.889 1.00 102.75 ? 716 GLU C OE2 1 
ATOM   14623 N N   . LYS C 1 717 ? 153.890 142.138 103.430 1.00 102.47 ? 717 LYS C N   1 
ATOM   14624 C CA  . LYS C 1 717 ? 152.699 142.100 102.570 1.00 102.53 ? 717 LYS C CA  1 
ATOM   14625 C C   . LYS C 1 717 ? 152.825 142.973 101.312 1.00 100.79 ? 717 LYS C C   1 
ATOM   14626 O O   . LYS C 1 717 ? 152.038 142.816 100.384 1.00 101.92 ? 717 LYS C O   1 
ATOM   14627 C CB  . LYS C 1 717 ? 151.472 142.479 103.415 1.00 98.34  ? 717 LYS C CB  1 
ATOM   14628 C CG  . LYS C 1 717 ? 151.239 141.459 104.541 1.00 100.11 ? 717 LYS C CG  1 
ATOM   14629 C CD  . LYS C 1 717 ? 150.125 141.894 105.498 1.00 103.56 ? 717 LYS C CD  1 
ATOM   14630 C CE  . LYS C 1 717 ? 150.057 140.890 106.654 1.00 101.38 ? 717 LYS C CE  1 
ATOM   14631 N NZ  . LYS C 1 717 ? 149.013 141.256 107.639 1.00 98.96  ? 717 LYS C NZ  1 
ATOM   14632 N N   . THR C 1 718 ? 153.821 143.861 101.253 1.00 96.19  ? 718 THR C N   1 
ATOM   14633 C CA  . THR C 1 718 ? 154.131 144.709 100.084 1.00 98.31  ? 718 THR C CA  1 
ATOM   14634 C C   . THR C 1 718 ? 155.217 144.134 99.165  1.00 98.85  ? 718 THR C C   1 
ATOM   14635 O O   . THR C 1 718 ? 155.455 144.678 98.087  1.00 97.12  ? 718 THR C O   1 
ATOM   14636 C CB  . THR C 1 718 ? 154.530 146.134 100.504 1.00 103.64 ? 718 THR C CB  1 
ATOM   14637 O OG1 . THR C 1 718 ? 155.829 146.192 101.051 1.00 101.46 ? 718 THR C OG1 1 
ATOM   14638 C CG2 . THR C 1 718 ? 153.571 146.744 101.519 1.00 99.41  ? 718 THR C CG2 1 
ATOM   14639 N N   . LEU C 1 719 ? 155.896 143.051 99.557  1.00 100.28 ? 719 LEU C N   1 
ATOM   14640 C CA  . LEU C 1 719 ? 157.003 142.477 98.789  1.00 103.20 ? 719 LEU C CA  1 
ATOM   14641 C C   . LEU C 1 719 ? 156.534 141.895 97.444  1.00 100.32 ? 719 LEU C C   1 
ATOM   14642 O O   . LEU C 1 719 ? 155.882 140.849 97.382  1.00 99.11  ? 719 LEU C O   1 
ATOM   14643 C CB  . LEU C 1 719 ? 157.776 141.458 99.651  1.00 100.14 ? 719 LEU C CB  1 
ATOM   14644 C CG  . LEU C 1 719 ? 158.368 142.031 100.953 1.00 96.94  ? 719 LEU C CG  1 
ATOM   14645 C CD1 . LEU C 1 719 ? 159.111 140.944 101.721 1.00 97.03  ? 719 LEU C CD1 1 
ATOM   14646 C CD2 . LEU C 1 719 ? 159.348 143.164 100.707 1.00 92.34  ? 719 LEU C CD2 1 
ATOM   14647 N N   . ARG D 1 74  ? 181.748 174.398 89.221  1.00 168.48 ? 74  ARG D N   1 
ATOM   14648 C CA  . ARG D 1 74  ? 182.481 174.205 90.501  1.00 168.86 ? 74  ARG D CA  1 
ATOM   14649 C C   . ARG D 1 74  ? 182.579 172.704 90.796  1.00 170.27 ? 74  ARG D C   1 
ATOM   14650 O O   . ARG D 1 74  ? 183.696 172.282 91.152  1.00 170.55 ? 74  ARG D O   1 
ATOM   14651 C CB  . ARG D 1 74  ? 181.782 174.983 91.636  1.00 168.45 ? 74  ARG D CB  1 
ATOM   14652 N N   . PHE D 1 75  ? 181.508 171.905 90.682  1.00 167.79 ? 75  PHE D N   1 
ATOM   14653 C CA  . PHE D 1 75  ? 181.493 170.478 91.095  1.00 166.40 ? 75  PHE D CA  1 
ATOM   14654 C C   . PHE D 1 75  ? 181.893 170.228 92.565  1.00 165.82 ? 75  PHE D C   1 
ATOM   14655 O O   . PHE D 1 75  ? 182.636 169.305 92.904  1.00 165.60 ? 75  PHE D O   1 
ATOM   14656 C CB  . PHE D 1 75  ? 182.224 169.577 90.086  1.00 166.49 ? 75  PHE D CB  1 
ATOM   14657 C CG  . PHE D 1 75  ? 181.453 169.369 88.803  1.00 167.45 ? 75  PHE D CG  1 
ATOM   14658 C CD1 . PHE D 1 75  ? 180.289 168.577 88.809  1.00 166.84 ? 75  PHE D CD1 1 
ATOM   14659 C CD2 . PHE D 1 75  ? 181.886 169.967 87.606  1.00 166.78 ? 75  PHE D CD2 1 
ATOM   14660 C CE1 . PHE D 1 75  ? 179.561 168.380 87.625  1.00 166.99 ? 75  PHE D CE1 1 
ATOM   14661 C CE2 . PHE D 1 75  ? 181.152 169.778 86.426  1.00 166.30 ? 75  PHE D CE2 1 
ATOM   14662 C CZ  . PHE D 1 75  ? 179.997 168.980 86.432  1.00 166.85 ? 75  PHE D CZ  1 
ATOM   14663 N N   . ASP D 1 76  ? 181.349 171.016 93.373  1.00 161.82 ? 76  ASP D N   1 
ATOM   14664 C CA  . ASP D 1 76  ? 181.253 170.681 94.794  1.00 161.88 ? 76  ASP D CA  1 
ATOM   14665 C C   . ASP D 1 76  ? 180.231 169.548 95.041  1.00 162.31 ? 76  ASP D C   1 
ATOM   14666 O O   . ASP D 1 76  ? 179.506 169.107 94.139  1.00 162.20 ? 76  ASP D O   1 
ATOM   14667 C CB  . ASP D 1 76  ? 180.939 171.957 95.602  1.00 160.98 ? 76  ASP D CB  1 
ATOM   14668 C CG  . ASP D 1 76  ? 179.645 172.698 95.220  1.00 161.24 ? 76  ASP D CG  1 
ATOM   14669 O OD1 . ASP D 1 76  ? 178.739 172.094 94.613  1.00 161.92 ? 76  ASP D OD1 1 
ATOM   14670 O OD2 . ASP D 1 76  ? 179.556 173.903 95.545  1.00 159.88 ? 76  ASP D OD2 1 
ATOM   14671 N N   . ARG D 1 77  ? 180.141 169.123 96.307  1.00 152.29 ? 77  ARG D N   1 
ATOM   14672 C CA  . ARG D 1 77  ? 179.226 168.014 96.697  1.00 153.02 ? 77  ARG D CA  1 
ATOM   14673 C C   . ARG D 1 77  ? 177.763 168.362 96.430  1.00 152.39 ? 77  ARG D C   1 
ATOM   14674 O O   . ARG D 1 77  ? 177.027 167.472 95.960  1.00 152.53 ? 77  ARG D O   1 
ATOM   14675 C CB  . ARG D 1 77  ? 179.381 167.766 98.202  1.00 150.72 ? 77  ARG D CB  1 
ATOM   14676 C CG  . ARG D 1 77  ? 178.512 166.604 98.706  1.00 152.66 ? 77  ARG D CG  1 
ATOM   14677 C CD  . ARG D 1 77  ? 178.396 166.603 100.227 1.00 152.24 ? 77  ARG D CD  1 
ATOM   14678 N NE  . ARG D 1 77  ? 177.620 167.758 100.704 1.00 152.20 ? 77  ARG D NE  1 
ATOM   14679 C CZ  . ARG D 1 77  ? 177.285 167.966 101.972 1.00 151.69 ? 77  ARG D CZ  1 
ATOM   14680 N NH1 . ARG D 1 77  ? 176.584 169.037 102.303 1.00 150.82 ? 77  ARG D NH1 1 
ATOM   14681 N NH2 . ARG D 1 77  ? 177.648 167.102 102.903 1.00 150.21 ? 77  ARG D NH2 1 
ATOM   14682 N N   . ASP D 1 78  ? 177.357 169.600 96.710  1.00 152.83 ? 78  ASP D N   1 
ATOM   14683 C CA  . ASP D 1 78  ? 175.949 169.984 96.617  1.00 152.68 ? 78  ASP D CA  1 
ATOM   14684 C C   . ASP D 1 78  ? 175.471 170.089 95.155  1.00 152.32 ? 78  ASP D C   1 
ATOM   14685 O O   . ASP D 1 78  ? 174.337 169.694 94.852  1.00 153.06 ? 78  ASP D O   1 
ATOM   14686 C CB  . ASP D 1 78  ? 175.705 171.271 97.414  1.00 154.38 ? 78  ASP D CB  1 
ATOM   14687 C CG  . ASP D 1 78  ? 176.056 171.178 98.913  1.00 155.02 ? 78  ASP D CG  1 
ATOM   14688 O OD1 . ASP D 1 78  ? 176.245 170.069 99.467  1.00 156.02 ? 78  ASP D OD1 1 
ATOM   14689 O OD2 . ASP D 1 78  ? 176.120 172.248 99.560  1.00 153.83 ? 78  ASP D OD2 1 
ATOM   14690 N N   . ARG D 1 79  ? 176.339 170.480 94.205  1.00 156.28 ? 79  ARG D N   1 
ATOM   14691 C CA  . ARG D 1 79  ? 176.058 170.264 92.774  1.00 158.03 ? 79  ARG D CA  1 
ATOM   14692 C C   . ARG D 1 79  ? 175.957 168.774 92.463  1.00 158.93 ? 79  ARG D C   1 
ATOM   14693 O O   . ARG D 1 79  ? 174.953 168.346 91.909  1.00 157.44 ? 79  ARG D O   1 
ATOM   14694 C CB  . ARG D 1 79  ? 177.089 170.955 91.855  1.00 157.76 ? 79  ARG D CB  1 
ATOM   14695 C CG  . ARG D 1 79  ? 176.733 170.707 90.373  1.00 158.69 ? 79  ARG D CG  1 
ATOM   14696 C CD  . ARG D 1 79  ? 177.698 171.359 89.380  1.00 157.88 ? 79  ARG D CD  1 
ATOM   14697 N NE  . ARG D 1 79  ? 177.462 170.874 88.003  1.00 158.99 ? 79  ARG D NE  1 
ATOM   14698 C CZ  . ARG D 1 79  ? 176.562 171.307 87.138  1.00 157.86 ? 79  ARG D CZ  1 
ATOM   14699 N NH1 . ARG D 1 79  ? 176.413 170.721 85.987  1.00 157.52 ? 79  ARG D NH1 1 
ATOM   14700 N NH2 . ARG D 1 79  ? 175.788 172.319 87.392  1.00 156.82 ? 79  ARG D NH2 1 
ATOM   14701 N N   . LEU D 1 80  ? 176.962 167.966 92.803  1.00 154.57 ? 80  LEU D N   1 
ATOM   14702 C CA  . LEU D 1 80  ? 176.964 166.557 92.399  1.00 152.06 ? 80  LEU D CA  1 
ATOM   14703 C C   . LEU D 1 80  ? 175.758 165.781 92.956  1.00 151.87 ? 80  LEU D C   1 
ATOM   14704 O O   . LEU D 1 80  ? 175.084 165.073 92.215  1.00 152.02 ? 80  LEU D O   1 
ATOM   14705 C CB  . LEU D 1 80  ? 178.300 165.905 92.787  1.00 151.79 ? 80  LEU D CB  1 
ATOM   14706 C CG  . LEU D 1 80  ? 178.398 164.427 92.373  1.00 152.15 ? 80  LEU D CG  1 
ATOM   14707 C CD1 . LEU D 1 80  ? 178.186 164.232 90.879  1.00 152.64 ? 80  LEU D CD1 1 
ATOM   14708 C CD2 . LEU D 1 80  ? 179.782 163.900 92.718  1.00 151.57 ? 80  LEU D CD2 1 
ATOM   14709 N N   . PHE D 1 81  ? 175.436 165.956 94.237  1.00 144.75 ? 81  PHE D N   1 
ATOM   14710 C CA  . PHE D 1 81  ? 174.308 165.290 94.889  1.00 143.59 ? 81  PHE D CA  1 
ATOM   14711 C C   . PHE D 1 81  ? 172.962 165.723 94.301  1.00 144.20 ? 81  PHE D C   1 
ATOM   14712 O O   . PHE D 1 81  ? 172.043 164.912 94.219  1.00 145.01 ? 81  PHE D O   1 
ATOM   14713 C CB  . PHE D 1 81  ? 174.325 165.579 96.396  1.00 143.82 ? 81  PHE D CB  1 
ATOM   14714 C CG  . PHE D 1 81  ? 175.280 164.760 97.249  1.00 145.67 ? 81  PHE D CG  1 
ATOM   14715 C CD1 . PHE D 1 81  ? 176.475 164.212 96.742  1.00 145.86 ? 81  PHE D CD1 1 
ATOM   14716 C CD2 . PHE D 1 81  ? 174.954 164.551 98.598  1.00 144.08 ? 81  PHE D CD2 1 
ATOM   14717 C CE1 . PHE D 1 81  ? 177.324 163.468 97.577  1.00 145.65 ? 81  PHE D CE1 1 
ATOM   14718 C CE2 . PHE D 1 81  ? 175.799 163.800 99.427  1.00 143.96 ? 81  PHE D CE2 1 
ATOM   14719 C CZ  . PHE D 1 81  ? 176.983 163.255 98.917  1.00 145.38 ? 81  PHE D CZ  1 
ATOM   14720 N N   . SER D 1 82  ? 172.814 166.975 93.861  1.00 150.25 ? 82  SER D N   1 
ATOM   14721 C CA  . SER D 1 82  ? 171.597 167.405 93.158  1.00 149.77 ? 82  SER D CA  1 
ATOM   14722 C C   . SER D 1 82  ? 171.568 166.928 91.691  1.00 149.46 ? 82  SER D C   1 
ATOM   14723 O O   . SER D 1 82  ? 170.506 166.546 91.204  1.00 148.02 ? 82  SER D O   1 
ATOM   14724 C CB  . SER D 1 82  ? 171.384 168.914 93.313  1.00 148.64 ? 82  SER D CB  1 
ATOM   14725 O OG  . SER D 1 82  ? 172.458 169.679 92.819  1.00 149.29 ? 82  SER D OG  1 
ATOM   14726 N N   . VAL D 1 83  ? 172.716 166.817 91.010  1.00 148.73 ? 83  VAL D N   1 
ATOM   14727 C CA  . VAL D 1 83  ? 172.832 166.241 89.651  1.00 148.38 ? 83  VAL D CA  1 
ATOM   14728 C C   . VAL D 1 83  ? 172.428 164.766 89.605  1.00 148.44 ? 83  VAL D C   1 
ATOM   14729 O O   . VAL D 1 83  ? 171.515 164.403 88.862  1.00 146.48 ? 83  VAL D O   1 
ATOM   14730 C CB  . VAL D 1 83  ? 174.254 166.449 89.080  1.00 148.13 ? 83  VAL D CB  1 
ATOM   14731 C CG1 . VAL D 1 83  ? 174.568 165.579 87.857  1.00 148.82 ? 83  VAL D CG1 1 
ATOM   14732 C CG2 . VAL D 1 83  ? 174.444 167.907 88.647  1.00 148.71 ? 83  VAL D CG2 1 
ATOM   14733 N N   . VAL D 1 84  ? 173.041 163.903 90.425  1.00 146.41 ? 84  VAL D N   1 
ATOM   14734 C CA  . VAL D 1 84  ? 172.732 162.457 90.403  1.00 144.17 ? 84  VAL D CA  1 
ATOM   14735 C C   . VAL D 1 84  ? 171.309 162.138 90.874  1.00 143.65 ? 84  VAL D C   1 
ATOM   14736 O O   . VAL D 1 84  ? 170.768 161.096 90.506  1.00 142.74 ? 84  VAL D O   1 
ATOM   14737 C CB  . VAL D 1 84  ? 173.755 161.619 91.185  1.00 143.89 ? 84  VAL D CB  1 
ATOM   14738 C CG1 . VAL D 1 84  ? 175.167 161.814 90.638  1.00 143.83 ? 84  VAL D CG1 1 
ATOM   14739 C CG2 . VAL D 1 84  ? 173.741 161.881 92.691  1.00 142.29 ? 84  VAL D CG2 1 
ATOM   14740 N N   . SER D 1 85  ? 170.668 163.039 91.632  1.00 144.34 ? 85  SER D N   1 
ATOM   14741 C CA  . SER D 1 85  ? 169.263 162.882 92.038  1.00 144.57 ? 85  SER D CA  1 
ATOM   14742 C C   . SER D 1 85  ? 168.263 163.086 90.889  1.00 142.52 ? 85  SER D C   1 
ATOM   14743 O O   . SER D 1 85  ? 167.182 162.507 90.928  1.00 139.37 ? 85  SER D O   1 
ATOM   14744 C CB  . SER D 1 85  ? 168.911 163.858 93.164  1.00 142.66 ? 85  SER D CB  1 
ATOM   14745 O OG  . SER D 1 85  ? 169.717 163.650 94.310  1.00 141.96 ? 85  SER D OG  1 
ATOM   14746 N N   . ARG D 1 86  ? 168.655 163.851 89.854  1.00 150.85 ? 86  ARG D N   1 
ATOM   14747 C CA  . ARG D 1 86  ? 167.755 164.158 88.696  1.00 151.89 ? 86  ARG D CA  1 
ATOM   14748 C C   . ARG D 1 86  ? 167.747 163.011 87.677  1.00 152.15 ? 86  ARG D C   1 
ATOM   14749 O O   . ARG D 1 86  ? 166.761 162.913 86.921  1.00 150.76 ? 86  ARG D O   1 
ATOM   14750 C CB  . ARG D 1 86  ? 168.172 165.472 88.009  1.00 150.48 ? 86  ARG D CB  1 
ATOM   14751 C CG  . ARG D 1 86  ? 167.734 166.709 88.804  1.00 150.09 ? 86  ARG D CG  1 
ATOM   14752 C CD  . ARG D 1 86  ? 167.943 168.004 88.005  1.00 149.41 ? 86  ARG D CD  1 
ATOM   14753 N NE  . ARG D 1 86  ? 169.363 168.386 87.870  1.00 150.26 ? 86  ARG D NE  1 
ATOM   14754 C CZ  . ARG D 1 86  ? 170.083 168.964 88.825  1.00 150.99 ? 86  ARG D CZ  1 
ATOM   14755 N NH1 . ARG D 1 86  ? 171.351 169.267 88.605  1.00 148.99 ? 86  ARG D NH1 1 
ATOM   14756 N NH2 . ARG D 1 86  ? 169.537 169.231 89.997  1.00 151.28 ? 86  ARG D NH2 1 
ATOM   14757 N N   . GLY D 1 87  ? 168.793 162.186 87.654  1.00 153.16 ? 87  GLY D N   1 
ATOM   14758 C CA  . GLY D 1 87  ? 168.929 161.077 86.701  1.00 150.66 ? 87  GLY D CA  1 
ATOM   14759 C C   . GLY D 1 87  ? 169.422 161.482 85.305  1.00 152.76 ? 87  GLY D C   1 
ATOM   14760 O O   . GLY D 1 87  ? 169.392 160.659 84.393  1.00 150.84 ? 87  GLY D O   1 
ATOM   14761 N N   . VAL D 1 88  ? 169.885 162.725 85.120  1.00 162.08 ? 88  VAL D N   1 
ATOM   14762 C CA  . VAL D 1 88  ? 170.455 163.219 83.853  1.00 162.16 ? 88  VAL D CA  1 
ATOM   14763 C C   . VAL D 1 88  ? 171.987 163.080 83.884  1.00 161.67 ? 88  VAL D C   1 
ATOM   14764 O O   . VAL D 1 88  ? 172.638 163.782 84.658  1.00 159.71 ? 88  VAL D O   1 
ATOM   14765 C CB  . VAL D 1 88  ? 170.045 164.686 83.599  1.00 159.88 ? 88  VAL D CB  1 
ATOM   14766 C CG1 . VAL D 1 88  ? 170.641 165.222 82.293  1.00 158.45 ? 88  VAL D CG1 1 
ATOM   14767 C CG2 . VAL D 1 88  ? 168.523 164.820 83.504  1.00 158.01 ? 88  VAL D CG2 1 
ATOM   14768 N N   . PRO D 1 89  ? 172.600 162.215 83.052  1.00 159.88 ? 89  PRO D N   1 
ATOM   14769 C CA  . PRO D 1 89  ? 174.039 161.954 83.121  1.00 158.93 ? 89  PRO D CA  1 
ATOM   14770 C C   . PRO D 1 89  ? 174.891 163.092 82.546  1.00 159.23 ? 89  PRO D C   1 
ATOM   14771 O O   . PRO D 1 89  ? 176.043 163.268 82.933  1.00 157.55 ? 89  PRO D O   1 
ATOM   14772 C CB  . PRO D 1 89  ? 174.242 160.664 82.323  1.00 158.39 ? 89  PRO D CB  1 
ATOM   14773 C CG  . PRO D 1 89  ? 173.103 160.673 81.308  1.00 158.14 ? 89  PRO D CG  1 
ATOM   14774 C CD  . PRO D 1 89  ? 171.965 161.342 82.072  1.00 157.81 ? 89  PRO D CD  1 
ATOM   14775 N N   . GLU D 1 90  ? 174.346 163.877 81.616  1.00 163.61 ? 90  GLU D N   1 
ATOM   14776 C CA  . GLU D 1 90  ? 175.120 164.869 80.853  1.00 162.84 ? 90  GLU D CA  1 
ATOM   14777 C C   . GLU D 1 90  ? 175.618 166.047 81.711  1.00 163.88 ? 90  GLU D C   1 
ATOM   14778 O O   . GLU D 1 90  ? 176.666 166.632 81.435  1.00 163.70 ? 90  GLU D O   1 
ATOM   14779 C CB  . GLU D 1 90  ? 174.267 165.390 79.685  1.00 160.58 ? 90  GLU D CB  1 
ATOM   14780 N N   . GLU D 1 91  ? 174.918 166.372 82.801  1.00 164.32 ? 91  GLU D N   1 
ATOM   14781 C CA  . GLU D 1 91  ? 175.299 167.444 83.731  1.00 163.19 ? 91  GLU D CA  1 
ATOM   14782 C C   . GLU D 1 91  ? 176.564 167.133 84.562  1.00 163.63 ? 91  GLU D C   1 
ATOM   14783 O O   . GLU D 1 91  ? 177.087 168.024 85.233  1.00 163.04 ? 91  GLU D O   1 
ATOM   14784 C CB  . GLU D 1 91  ? 174.108 167.789 84.641  1.00 163.43 ? 91  GLU D CB  1 
ATOM   14785 C CG  . GLU D 1 91  ? 172.916 168.344 83.849  1.00 163.68 ? 91  GLU D CG  1 
ATOM   14786 C CD  . GLU D 1 91  ? 171.904 169.085 84.735  1.00 164.38 ? 91  GLU D CD  1 
ATOM   14787 O OE1 . GLU D 1 91  ? 171.524 168.575 85.812  1.00 163.80 ? 91  GLU D OE1 1 
ATOM   14788 O OE2 . GLU D 1 91  ? 171.486 170.199 84.349  1.00 163.68 ? 91  GLU D OE2 1 
ATOM   14789 N N   . LEU D 1 92  ? 177.093 165.904 84.481  1.00 164.92 ? 92  LEU D N   1 
ATOM   14790 C CA  . LEU D 1 92  ? 178.400 165.517 85.028  1.00 165.36 ? 92  LEU D CA  1 
ATOM   14791 C C   . LEU D 1 92  ? 179.585 166.031 84.180  1.00 164.13 ? 92  LEU D C   1 
ATOM   14792 O O   . LEU D 1 92  ? 180.741 165.871 84.573  1.00 163.64 ? 92  LEU D O   1 
ATOM   14793 C CB  . LEU D 1 92  ? 178.463 163.978 85.163  1.00 164.77 ? 92  LEU D CB  1 
ATOM   14794 C CG  . LEU D 1 92  ? 177.412 163.347 86.094  1.00 164.40 ? 92  LEU D CG  1 
ATOM   14795 C CD1 . LEU D 1 92  ? 177.375 161.829 85.923  1.00 164.36 ? 92  LEU D CD1 1 
ATOM   14796 C CD2 . LEU D 1 92  ? 177.731 163.641 87.559  1.00 162.78 ? 92  LEU D CD2 1 
ATOM   14797 N N   . THR D 1 93  ? 179.334 166.634 83.011  1.00 167.27 ? 93  THR D N   1 
ATOM   14798 C CA  . THR D 1 93  ? 180.382 167.099 82.080  1.00 168.41 ? 93  THR D CA  1 
ATOM   14799 C C   . THR D 1 93  ? 181.336 168.098 82.751  1.00 168.85 ? 93  THR D C   1 
ATOM   14800 O O   . THR D 1 93  ? 180.927 169.186 83.153  1.00 169.47 ? 93  THR D O   1 
ATOM   14801 C CB  . THR D 1 93  ? 179.766 167.714 80.813  1.00 166.69 ? 93  THR D CB  1 
ATOM   14802 O OG1 . THR D 1 93  ? 179.008 166.745 80.130  1.00 166.49 ? 93  THR D OG1 1 
ATOM   14803 C CG2 . THR D 1 93  ? 180.820 168.201 79.820  1.00 166.21 ? 93  THR D CG2 1 
ATOM   14804 N N   . GLY D 1 94  ? 182.615 167.732 82.869  1.00 170.30 ? 94  GLY D N   1 
ATOM   14805 C CA  . GLY D 1 94  ? 183.655 168.515 83.545  1.00 170.34 ? 94  GLY D CA  1 
ATOM   14806 C C   . GLY D 1 94  ? 184.020 168.050 84.963  1.00 171.12 ? 94  GLY D C   1 
ATOM   14807 O O   . GLY D 1 94  ? 185.024 168.513 85.508  1.00 170.58 ? 94  GLY D O   1 
ATOM   14808 N N   . LEU D 1 95  ? 183.283 167.099 85.552  1.00 170.01 ? 95  LEU D N   1 
ATOM   14809 C CA  . LEU D 1 95  ? 183.612 166.546 86.872  1.00 169.67 ? 95  LEU D CA  1 
ATOM   14810 C C   . LEU D 1 95  ? 184.993 165.865 86.885  1.00 169.52 ? 95  LEU D C   1 
ATOM   14811 O O   . LEU D 1 95  ? 185.747 166.024 87.842  1.00 169.80 ? 95  LEU D O   1 
ATOM   14812 C CB  . LEU D 1 95  ? 182.480 165.589 87.294  1.00 169.12 ? 95  LEU D CB  1 
ATOM   14813 C CG  . LEU D 1 95  ? 182.674 164.867 88.644  1.00 169.26 ? 95  LEU D CG  1 
ATOM   14814 C CD1 . LEU D 1 95  ? 182.821 165.828 89.818  1.00 168.56 ? 95  LEU D CD1 1 
ATOM   14815 C CD2 . LEU D 1 95  ? 181.449 164.000 88.923  1.00 168.56 ? 95  LEU D CD2 1 
ATOM   14816 N N   . LEU D 1 96  ? 185.363 165.178 85.792  1.00 168.90 ? 96  LEU D N   1 
ATOM   14817 C CA  . LEU D 1 96  ? 186.694 164.576 85.635  1.00 168.66 ? 96  LEU D CA  1 
ATOM   14818 C C   . LEU D 1 96  ? 187.802 165.626 85.773  1.00 169.90 ? 96  LEU D C   1 
ATOM   14819 O O   . LEU D 1 96  ? 188.765 165.436 86.513  1.00 169.49 ? 96  LEU D O   1 
ATOM   14820 C CB  . LEU D 1 96  ? 186.851 163.891 84.261  1.00 169.72 ? 96  LEU D CB  1 
ATOM   14821 C CG  . LEU D 1 96  ? 185.878 162.746 83.938  1.00 169.53 ? 96  LEU D CG  1 
ATOM   14822 C CD1 . LEU D 1 96  ? 184.583 163.253 83.293  1.00 169.28 ? 96  LEU D CD1 1 
ATOM   14823 C CD2 . LEU D 1 96  ? 186.528 161.774 82.958  1.00 168.05 ? 96  LEU D CD2 1 
ATOM   14824 N N   . GLU D 1 97  ? 187.670 166.750 85.065  1.00 172.75 ? 97  GLU D N   1 
ATOM   14825 C CA  . GLU D 1 97  ? 188.670 167.821 85.068  1.00 171.98 ? 97  GLU D CA  1 
ATOM   14826 C C   . GLU D 1 97  ? 188.806 168.459 86.452  1.00 172.68 ? 97  GLU D C   1 
ATOM   14827 O O   . GLU D 1 97  ? 189.923 168.679 86.913  1.00 170.83 ? 97  GLU D O   1 
ATOM   14828 C CB  . GLU D 1 97  ? 188.312 168.898 84.036  1.00 169.59 ? 97  GLU D CB  1 
ATOM   14829 N N   . TYR D 1 98  ? 187.693 168.708 87.148  1.00 173.59 ? 98  TYR D N   1 
ATOM   14830 C CA  . TYR D 1 98  ? 187.742 169.298 88.486  1.00 172.90 ? 98  TYR D CA  1 
ATOM   14831 C C   . TYR D 1 98  ? 188.399 168.363 89.510  1.00 173.08 ? 98  TYR D C   1 
ATOM   14832 O O   . TYR D 1 98  ? 189.264 168.800 90.272  1.00 173.24 ? 98  TYR D O   1 
ATOM   14833 C CB  . TYR D 1 98  ? 186.336 169.696 88.936  1.00 172.63 ? 98  TYR D CB  1 
ATOM   14834 C CG  . TYR D 1 98  ? 186.347 170.465 90.242  1.00 173.38 ? 98  TYR D CG  1 
ATOM   14835 C CD1 . TYR D 1 98  ? 186.740 171.818 90.249  1.00 172.92 ? 98  TYR D CD1 1 
ATOM   14836 C CD2 . TYR D 1 98  ? 186.003 169.832 91.451  1.00 172.51 ? 98  TYR D CD2 1 
ATOM   14837 C CE1 . TYR D 1 98  ? 186.755 172.546 91.456  1.00 172.88 ? 98  TYR D CE1 1 
ATOM   14838 C CE2 . TYR D 1 98  ? 186.021 170.554 92.659  1.00 172.91 ? 98  TYR D CE2 1 
ATOM   14839 C CZ  . TYR D 1 98  ? 186.382 171.919 92.662  1.00 173.61 ? 98  TYR D CZ  1 
ATOM   14840 O OH  . TYR D 1 98  ? 186.381 172.631 93.819  1.00 171.77 ? 98  TYR D OH  1 
ATOM   14841 N N   . LEU D 1 99  ? 188.041 167.075 89.512  1.00 172.99 ? 99  LEU D N   1 
ATOM   14842 C CA  . LEU D 1 99  ? 188.641 166.076 90.404  1.00 173.81 ? 99  LEU D CA  1 
ATOM   14843 C C   . LEU D 1 99  ? 190.149 165.942 90.156  1.00 173.47 ? 99  LEU D C   1 
ATOM   14844 O O   . LEU D 1 99  ? 190.938 166.025 91.098  1.00 172.04 ? 99  LEU D O   1 
ATOM   14845 C CB  . LEU D 1 99  ? 187.935 164.724 90.215  1.00 173.48 ? 99  LEU D CB  1 
ATOM   14846 C CG  . LEU D 1 99  ? 186.491 164.683 90.741  1.00 173.13 ? 99  LEU D CG  1 
ATOM   14847 C CD1 . LEU D 1 99  ? 185.835 163.383 90.286  1.00 172.85 ? 99  LEU D CD1 1 
ATOM   14848 C CD2 . LEU D 1 99  ? 186.419 164.759 92.265  1.00 170.64 ? 99  LEU D CD2 1 
ATOM   14849 N N   . ARG D 1 100 ? 190.570 165.819 88.890  1.00 175.73 ? 100 ARG D N   1 
ATOM   14850 C CA  . ARG D 1 100 ? 191.992 165.734 88.514  1.00 175.75 ? 100 ARG D CA  1 
ATOM   14851 C C   . ARG D 1 100 ? 192.774 167.005 88.852  1.00 175.90 ? 100 ARG D C   1 
ATOM   14852 O O   . ARG D 1 100 ? 193.870 166.910 89.401  1.00 175.95 ? 100 ARG D O   1 
ATOM   14853 C CB  . ARG D 1 100 ? 192.115 165.405 87.019  1.00 174.90 ? 100 ARG D CB  1 
ATOM   14854 C CG  . ARG D 1 100 ? 191.762 163.941 86.723  1.00 174.09 ? 100 ARG D CG  1 
ATOM   14855 C CD  . ARG D 1 100 ? 191.850 163.674 85.219  1.00 173.86 ? 100 ARG D CD  1 
ATOM   14856 N NE  . ARG D 1 100 ? 191.727 162.241 84.905  1.00 175.81 ? 100 ARG D NE  1 
ATOM   14857 C CZ  . ARG D 1 100 ? 191.859 161.685 83.717  1.00 175.45 ? 100 ARG D CZ  1 
ATOM   14858 N NH1 . ARG D 1 100 ? 191.771 160.398 83.590  1.00 174.36 ? 100 ARG D NH1 1 
ATOM   14859 N NH2 . ARG D 1 100 ? 192.074 162.382 82.641  1.00 174.77 ? 100 ARG D NH2 1 
ATOM   14860 N N   . TRP D 1 101 ? 192.220 168.188 88.585  1.00 177.48 ? 101 TRP D N   1 
ATOM   14861 C CA  . TRP D 1 101 ? 192.896 169.467 88.842  1.00 177.61 ? 101 TRP D CA  1 
ATOM   14862 C C   . TRP D 1 101 ? 193.093 169.739 90.342  1.00 177.80 ? 101 TRP D C   1 
ATOM   14863 O O   . TRP D 1 101 ? 194.148 170.219 90.752  1.00 176.21 ? 101 TRP D O   1 
ATOM   14864 C CB  . TRP D 1 101 ? 192.118 170.592 88.143  1.00 177.18 ? 101 TRP D CB  1 
ATOM   14865 C CG  . TRP D 1 101 ? 192.783 171.934 88.119  1.00 178.34 ? 101 TRP D CG  1 
ATOM   14866 C CD1 . TRP D 1 101 ? 193.569 172.388 87.115  1.00 177.28 ? 101 TRP D CD1 1 
ATOM   14867 C CD2 . TRP D 1 101 ? 192.772 173.000 89.121  1.00 179.09 ? 101 TRP D CD2 1 
ATOM   14868 N NE1 . TRP D 1 101 ? 194.034 173.650 87.417  1.00 177.77 ? 101 TRP D NE1 1 
ATOM   14869 C CE2 . TRP D 1 101 ? 193.579 174.078 88.644  1.00 179.18 ? 101 TRP D CE2 1 
ATOM   14870 C CE3 . TRP D 1 101 ? 192.168 173.172 90.384  1.00 177.55 ? 101 TRP D CE3 1 
ATOM   14871 C CZ2 . TRP D 1 101 ? 193.780 175.254 89.380  1.00 177.81 ? 101 TRP D CZ2 1 
ATOM   14872 C CZ3 . TRP D 1 101 ? 192.361 174.348 91.132  1.00 176.74 ? 101 TRP D CZ3 1 
ATOM   14873 C CH2 . TRP D 1 101 ? 193.165 175.389 90.634  1.00 177.01 ? 101 TRP D CH2 1 
ATOM   14874 N N   . ASN D 1 102 ? 192.122 169.365 91.182  1.00 177.50 ? 102 ASN D N   1 
ATOM   14875 C CA  . ASN D 1 102 ? 192.249 169.425 92.645  1.00 177.02 ? 102 ASN D CA  1 
ATOM   14876 C C   . ASN D 1 102 ? 193.003 168.217 93.251  1.00 177.42 ? 102 ASN D C   1 
ATOM   14877 O O   . ASN D 1 102 ? 193.387 168.267 94.418  1.00 177.32 ? 102 ASN D O   1 
ATOM   14878 C CB  . ASN D 1 102 ? 190.855 169.582 93.274  1.00 177.84 ? 102 ASN D CB  1 
ATOM   14879 C CG  . ASN D 1 102 ? 190.234 170.936 92.984  1.00 177.97 ? 102 ASN D CG  1 
ATOM   14880 O OD1 . ASN D 1 102 ? 190.443 171.904 93.699  1.00 176.83 ? 102 ASN D OD1 1 
ATOM   14881 N ND2 . ASN D 1 102 ? 189.451 171.044 91.942  1.00 177.69 ? 102 ASN D ND2 1 
ATOM   14882 N N   . SER D 1 103 ? 193.228 167.142 92.488  1.00 175.44 ? 103 SER D N   1 
ATOM   14883 C CA  . SER D 1 103 ? 193.758 165.832 92.925  1.00 175.40 ? 103 SER D CA  1 
ATOM   14884 C C   . SER D 1 103 ? 192.879 165.086 93.953  1.00 175.70 ? 103 SER D C   1 
ATOM   14885 O O   . SER D 1 103 ? 193.377 164.300 94.763  1.00 174.28 ? 103 SER D O   1 
ATOM   14886 C CB  . SER D 1 103 ? 195.244 165.927 93.315  1.00 174.43 ? 103 SER D CB  1 
ATOM   14887 O OG  . SER D 1 103 ? 195.439 166.578 94.558  1.00 175.43 ? 103 SER D OG  1 
ATOM   14888 N N   . LYS D 1 104 ? 191.561 165.332 93.936  1.00 171.66 ? 104 LYS D N   1 
ATOM   14889 C CA  . LYS D 1 104 ? 190.584 164.771 94.891  1.00 170.50 ? 104 LYS D CA  1 
ATOM   14890 C C   . LYS D 1 104 ? 189.810 163.584 94.312  1.00 171.29 ? 104 LYS D C   1 
ATOM   14891 O O   . LYS D 1 104 ? 189.783 163.382 93.100  1.00 170.39 ? 104 LYS D O   1 
ATOM   14892 C CB  . LYS D 1 104 ? 189.634 165.874 95.384  1.00 170.25 ? 104 LYS D CB  1 
ATOM   14893 C CG  . LYS D 1 104 ? 190.412 166.975 96.114  1.00 170.92 ? 104 LYS D CG  1 
ATOM   14894 C CD  . LYS D 1 104 ? 189.513 167.935 96.905  1.00 170.42 ? 104 LYS D CD  1 
ATOM   14895 C CE  . LYS D 1 104 ? 188.937 167.289 98.171  1.00 171.00 ? 104 LYS D CE  1 
ATOM   14896 N NZ  . LYS D 1 104 ? 189.987 167.003 99.180  1.00 170.60 ? 104 LYS D NZ  1 
ATOM   14897 N N   . TYR D 1 105 ? 189.150 162.824 95.188  1.00 164.08 ? 105 TYR D N   1 
ATOM   14898 C CA  . TYR D 1 105 ? 188.390 161.615 94.856  1.00 162.26 ? 105 TYR D CA  1 
ATOM   14899 C C   . TYR D 1 105 ? 186.944 161.681 95.374  1.00 161.39 ? 105 TYR D C   1 
ATOM   14900 O O   . TYR D 1 105 ? 186.692 162.227 96.447  1.00 160.84 ? 105 TYR D O   1 
ATOM   14901 C CB  . TYR D 1 105 ? 189.106 160.389 95.445  1.00 161.34 ? 105 TYR D CB  1 
ATOM   14902 C CG  . TYR D 1 105 ? 190.581 160.251 95.117  1.00 162.38 ? 105 TYR D CG  1 
ATOM   14903 C CD1 . TYR D 1 105 ? 190.994 159.999 93.796  1.00 162.22 ? 105 TYR D CD1 1 
ATOM   14904 C CD2 . TYR D 1 105 ? 191.541 160.344 96.143  1.00 161.17 ? 105 TYR D CD2 1 
ATOM   14905 C CE1 . TYR D 1 105 ? 192.360 159.821 93.506  1.00 161.96 ? 105 TYR D CE1 1 
ATOM   14906 C CE2 . TYR D 1 105 ? 192.908 160.181 95.852  1.00 161.84 ? 105 TYR D CE2 1 
ATOM   14907 C CZ  . TYR D 1 105 ? 193.320 159.909 94.533  1.00 162.09 ? 105 TYR D CZ  1 
ATOM   14908 O OH  . TYR D 1 105 ? 194.630 159.714 94.245  1.00 160.33 ? 105 TYR D OH  1 
ATOM   14909 N N   . LEU D 1 106 ? 185.999 161.045 94.675  1.00 150.03 ? 106 LEU D N   1 
ATOM   14910 C CA  . LEU D 1 106 ? 184.576 161.000 95.062  1.00 149.32 ? 106 LEU D CA  1 
ATOM   14911 C C   . LEU D 1 106 ? 184.298 160.274 96.395  1.00 151.31 ? 106 LEU D C   1 
ATOM   14912 O O   . LEU D 1 106 ? 183.198 160.382 96.934  1.00 150.36 ? 106 LEU D O   1 
ATOM   14913 C CB  . LEU D 1 106 ? 183.758 160.358 93.925  1.00 149.54 ? 106 LEU D CB  1 
ATOM   14914 C CG  . LEU D 1 106 ? 183.685 161.183 92.632  1.00 150.79 ? 106 LEU D CG  1 
ATOM   14915 C CD1 . LEU D 1 106 ? 182.898 160.409 91.579  1.00 149.77 ? 106 LEU D CD1 1 
ATOM   14916 C CD2 . LEU D 1 106 ? 182.989 162.519 92.866  1.00 152.39 ? 106 LEU D CD2 1 
ATOM   14917 N N   . THR D 1 107 ? 185.274 159.543 96.938  1.00 156.75 ? 107 THR D N   1 
ATOM   14918 C CA  . THR D 1 107 ? 185.200 158.888 98.261  1.00 155.38 ? 107 THR D CA  1 
ATOM   14919 C C   . THR D 1 107 ? 185.954 159.634 99.366  1.00 155.20 ? 107 THR D C   1 
ATOM   14920 O O   . THR D 1 107 ? 186.000 159.155 100.500 1.00 155.29 ? 107 THR D O   1 
ATOM   14921 C CB  . THR D 1 107 ? 185.646 157.418 98.195  1.00 154.37 ? 107 THR D CB  1 
ATOM   14922 O OG1 . THR D 1 107 ? 186.968 157.275 97.736  1.00 154.90 ? 107 THR D OG1 1 
ATOM   14923 C CG2 . THR D 1 107 ? 184.762 156.630 97.246  1.00 154.02 ? 107 THR D CG2 1 
ATOM   14924 N N   . ASP D 1 108 ? 186.528 160.811 99.090  1.00 155.88 ? 108 ASP D N   1 
ATOM   14925 C CA  . ASP D 1 108 ? 187.065 161.695 100.131 1.00 156.33 ? 108 ASP D CA  1 
ATOM   14926 C C   . ASP D 1 108 ? 185.933 162.415 100.891 1.00 156.00 ? 108 ASP D C   1 
ATOM   14927 O O   . ASP D 1 108 ? 184.856 162.649 100.342 1.00 155.96 ? 108 ASP D O   1 
ATOM   14928 C CB  . ASP D 1 108 ? 188.045 162.704 99.512  1.00 156.90 ? 108 ASP D CB  1 
ATOM   14929 C CG  . ASP D 1 108 ? 188.864 163.460 100.566 1.00 157.28 ? 108 ASP D CG  1 
ATOM   14930 O OD1 . ASP D 1 108 ? 189.012 162.952 101.697 1.00 156.00 ? 108 ASP D OD1 1 
ATOM   14931 O OD2 . ASP D 1 108 ? 189.346 164.572 100.264 1.00 157.10 ? 108 ASP D OD2 1 
ATOM   14932 N N   . SER D 1 109 ? 186.172 162.821 102.142 1.00 151.54 ? 109 SER D N   1 
ATOM   14933 C CA  . SER D 1 109 ? 185.156 163.404 103.043 1.00 152.67 ? 109 SER D CA  1 
ATOM   14934 C C   . SER D 1 109 ? 184.376 164.574 102.422 1.00 153.60 ? 109 SER D C   1 
ATOM   14935 O O   . SER D 1 109 ? 183.159 164.671 102.591 1.00 152.91 ? 109 SER D O   1 
ATOM   14936 C CB  . SER D 1 109 ? 185.842 163.856 104.338 1.00 151.35 ? 109 SER D CB  1 
ATOM   14937 O OG  . SER D 1 109 ? 184.918 164.432 105.238 1.00 150.29 ? 109 SER D OG  1 
ATOM   14938 N N   . ALA D 1 110 ? 185.043 165.398 101.610 1.00 152.06 ? 110 ALA D N   1 
ATOM   14939 C CA  . ALA D 1 110 ? 184.448 166.531 100.902 1.00 150.46 ? 110 ALA D CA  1 
ATOM   14940 C C   . ALA D 1 110 ? 183.243 166.173 100.005 1.00 151.80 ? 110 ALA D C   1 
ATOM   14941 O O   . ALA D 1 110 ? 182.428 167.049 99.737  1.00 152.76 ? 110 ALA D O   1 
ATOM   14942 C CB  . ALA D 1 110 ? 185.557 167.192 100.077 1.00 149.74 ? 110 ALA D CB  1 
ATOM   14943 N N   . TYR D 1 111 ? 183.095 164.915 99.574  1.00 152.16 ? 111 TYR D N   1 
ATOM   14944 C CA  . TYR D 1 111 ? 181.993 164.422 98.735  1.00 151.30 ? 111 TYR D CA  1 
ATOM   14945 C C   . TYR D 1 111 ? 181.007 163.511 99.491  1.00 150.40 ? 111 TYR D C   1 
ATOM   14946 O O   . TYR D 1 111 ? 180.338 162.677 98.887  1.00 150.07 ? 111 TYR D O   1 
ATOM   14947 C CB  . TYR D 1 111 ? 182.571 163.777 97.466  1.00 152.43 ? 111 TYR D CB  1 
ATOM   14948 C CG  . TYR D 1 111 ? 183.124 164.777 96.471  1.00 151.55 ? 111 TYR D CG  1 
ATOM   14949 C CD1 . TYR D 1 111 ? 182.260 165.349 95.519  1.00 150.52 ? 111 TYR D CD1 1 
ATOM   14950 C CD2 . TYR D 1 111 ? 184.481 165.140 96.495  1.00 151.87 ? 111 TYR D CD2 1 
ATOM   14951 C CE1 . TYR D 1 111 ? 182.749 166.285 94.591  1.00 152.32 ? 111 TYR D CE1 1 
ATOM   14952 C CE2 . TYR D 1 111 ? 184.968 166.091 95.581  1.00 151.83 ? 111 TYR D CE2 1 
ATOM   14953 C CZ  . TYR D 1 111 ? 184.103 166.666 94.630  1.00 153.69 ? 111 TYR D CZ  1 
ATOM   14954 O OH  . TYR D 1 111 ? 184.574 167.601 93.764  1.00 155.97 ? 111 TYR D OH  1 
ATOM   14955 N N   . THR D 1 112 ? 180.882 163.661 100.813 1.00 144.04 ? 112 THR D N   1 
ATOM   14956 C CA  . THR D 1 112 ? 180.005 162.830 101.656 1.00 145.72 ? 112 THR D CA  1 
ATOM   14957 C C   . THR D 1 112 ? 178.937 163.641 102.396 1.00 145.60 ? 112 THR D C   1 
ATOM   14958 O O   . THR D 1 112 ? 179.144 164.810 102.730 1.00 147.17 ? 112 THR D O   1 
ATOM   14959 C CB  . THR D 1 112 ? 180.809 161.971 102.641 1.00 146.74 ? 112 THR D CB  1 
ATOM   14960 O OG1 . THR D 1 112 ? 181.481 162.756 103.595 1.00 145.16 ? 112 THR D OG1 1 
ATOM   14961 C CG2 . THR D 1 112 ? 181.842 161.094 101.942 1.00 145.06 ? 112 THR D CG2 1 
ATOM   14962 N N   . GLU D 1 113 ? 177.759 163.048 102.624 1.00 141.01 ? 113 GLU D N   1 
ATOM   14963 C CA  . GLU D 1 113 ? 176.676 163.679 103.390 1.00 141.78 ? 113 GLU D CA  1 
ATOM   14964 C C   . GLU D 1 113 ? 177.046 163.849 104.878 1.00 142.07 ? 113 GLU D C   1 
ATOM   14965 O O   . GLU D 1 113 ? 177.861 163.105 105.426 1.00 140.63 ? 113 GLU D O   1 
ATOM   14966 C CB  . GLU D 1 113 ? 175.351 162.911 103.208 1.00 141.77 ? 113 GLU D CB  1 
ATOM   14967 C CG  . GLU D 1 113 ? 174.137 163.831 103.223 1.00 140.76 ? 113 GLU D CG  1 
ATOM   14968 C CD  . GLU D 1 113 ? 172.859 163.189 102.671 1.00 142.75 ? 113 GLU D CD  1 
ATOM   14969 O OE1 . GLU D 1 113 ? 172.317 162.260 103.296 1.00 142.30 ? 113 GLU D OE1 1 
ATOM   14970 O OE2 . GLU D 1 113 ? 172.369 163.621 101.612 1.00 143.85 ? 113 GLU D OE2 1 
ATOM   14971 N N   . GLY D 1 114 ? 176.468 164.849 105.548 1.00 142.83 ? 114 GLY D N   1 
ATOM   14972 C CA  . GLY D 1 114 ? 176.829 165.220 106.919 1.00 141.81 ? 114 GLY D CA  1 
ATOM   14973 C C   . GLY D 1 114 ? 176.492 164.164 107.976 1.00 143.13 ? 114 GLY D C   1 
ATOM   14974 O O   . GLY D 1 114 ? 175.471 163.480 107.890 1.00 142.31 ? 114 GLY D O   1 
ATOM   14975 N N   . SER D 1 115 ? 177.337 164.058 109.006 1.00 140.99 ? 115 SER D N   1 
ATOM   14976 C CA  . SER D 1 115 ? 177.205 163.126 110.145 1.00 139.73 ? 115 SER D CA  1 
ATOM   14977 C C   . SER D 1 115 ? 177.173 161.635 109.766 1.00 139.27 ? 115 SER D C   1 
ATOM   14978 O O   . SER D 1 115 ? 176.681 160.803 110.525 1.00 137.08 ? 115 SER D O   1 
ATOM   14979 C CB  . SER D 1 115 ? 176.034 163.514 111.062 1.00 138.79 ? 115 SER D CB  1 
ATOM   14980 O OG  . SER D 1 115 ? 176.166 164.857 111.491 1.00 138.05 ? 115 SER D OG  1 
ATOM   14981 N N   . THR D 1 116 ? 177.706 161.280 108.596 1.00 138.40 ? 116 THR D N   1 
ATOM   14982 C CA  . THR D 1 116 ? 177.807 159.905 108.077 1.00 137.46 ? 116 THR D CA  1 
ATOM   14983 C C   . THR D 1 116 ? 178.962 159.801 107.056 1.00 134.93 ? 116 THR D C   1 
ATOM   14984 O O   . THR D 1 116 ? 179.802 160.695 106.985 1.00 136.12 ? 116 THR D O   1 
ATOM   14985 C CB  . THR D 1 116 ? 176.436 159.458 107.525 1.00 134.07 ? 116 THR D CB  1 
ATOM   14986 O OG1 . THR D 1 116 ? 176.471 158.104 107.158 1.00 131.58 ? 116 THR D OG1 1 
ATOM   14987 C CG2 . THR D 1 116 ? 175.954 160.246 106.309 1.00 132.40 ? 116 THR D CG2 1 
ATOM   14988 N N   . GLY D 1 117 ? 179.039 158.723 106.271 1.00 121.64 ? 117 GLY D N   1 
ATOM   14989 C CA  . GLY D 1 117 ? 180.007 158.543 105.174 1.00 124.46 ? 117 GLY D CA  1 
ATOM   14990 C C   . GLY D 1 117 ? 179.369 158.460 103.781 1.00 124.93 ? 117 GLY D C   1 
ATOM   14991 O O   . GLY D 1 117 ? 180.044 158.163 102.801 1.00 125.66 ? 117 GLY D O   1 
ATOM   14992 N N   . LYS D 1 118 ? 178.055 158.679 103.702 1.00 121.52 ? 118 LYS D N   1 
ATOM   14993 C CA  . LYS D 1 118 ? 177.189 158.445 102.541 1.00 121.91 ? 118 LYS D CA  1 
ATOM   14994 C C   . LYS D 1 118 ? 177.655 159.209 101.302 1.00 120.73 ? 118 LYS D C   1 
ATOM   14995 O O   . LYS D 1 118 ? 177.763 160.431 101.343 1.00 125.48 ? 118 LYS D O   1 
ATOM   14996 C CB  . LYS D 1 118 ? 175.785 158.845 102.994 1.00 122.47 ? 118 LYS D CB  1 
ATOM   14997 C CG  . LYS D 1 118 ? 174.648 158.657 101.988 1.00 121.32 ? 118 LYS D CG  1 
ATOM   14998 C CD  . LYS D 1 118 ? 173.363 159.029 102.736 1.00 123.93 ? 118 LYS D CD  1 
ATOM   14999 C CE  . LYS D 1 118 ? 172.138 159.174 101.841 1.00 123.38 ? 118 LYS D CE  1 
ATOM   15000 N NZ  . LYS D 1 118 ? 171.051 159.860 102.581 1.00 125.35 ? 118 LYS D NZ  1 
ATOM   15001 N N   . THR D 1 119 ? 177.953 158.495 100.221 1.00 126.50 ? 119 THR D N   1 
ATOM   15002 C CA  . THR D 1 119 ? 178.576 159.038 99.001  1.00 129.18 ? 119 THR D CA  1 
ATOM   15003 C C   . THR D 1 119 ? 177.562 159.431 97.930  1.00 127.83 ? 119 THR D C   1 
ATOM   15004 O O   . THR D 1 119 ? 176.383 159.076 97.992  1.00 126.85 ? 119 THR D O   1 
ATOM   15005 C CB  . THR D 1 119 ? 179.581 158.041 98.398  1.00 131.26 ? 119 THR D CB  1 
ATOM   15006 O OG1 . THR D 1 119 ? 178.909 156.900 97.916  1.00 130.67 ? 119 THR D OG1 1 
ATOM   15007 C CG2 . THR D 1 119 ? 180.654 157.581 99.378  1.00 129.15 ? 119 THR D CG2 1 
ATOM   15008 N N   . CYS D 1 120 ? 178.037 160.097 96.882  1.00 131.76 ? 120 CYS D N   1 
ATOM   15009 C CA  . CYS D 1 120 ? 177.272 160.390 95.666  1.00 133.51 ? 120 CYS D CA  1 
ATOM   15010 C C   . CYS D 1 120 ? 176.671 159.146 94.997  1.00 135.32 ? 120 CYS D C   1 
ATOM   15011 O O   . CYS D 1 120 ? 175.565 159.220 94.471  1.00 134.36 ? 120 CYS D O   1 
ATOM   15012 C CB  . CYS D 1 120 ? 178.192 161.133 94.684  1.00 134.14 ? 120 CYS D CB  1 
ATOM   15013 S SG  . CYS D 1 120 ? 179.740 160.222 94.441  1.00 135.11 ? 120 CYS D SG  1 
ATOM   15014 N N   . LEU D 1 121 ? 177.331 157.984 95.051  1.00 128.91 ? 121 LEU D N   1 
ATOM   15015 C CA  . LEU D 1 121 ? 176.771 156.739 94.520  1.00 127.17 ? 121 LEU D CA  1 
ATOM   15016 C C   . LEU D 1 121 ? 175.559 156.271 95.339  1.00 127.63 ? 121 LEU D C   1 
ATOM   15017 O O   . LEU D 1 121 ? 174.563 155.843 94.766  1.00 130.87 ? 121 LEU D O   1 
ATOM   15018 C CB  . LEU D 1 121 ? 177.874 155.673 94.439  1.00 125.63 ? 121 LEU D CB  1 
ATOM   15019 C CG  . LEU D 1 121 ? 177.415 154.331 93.840  1.00 125.39 ? 121 LEU D CG  1 
ATOM   15020 C CD1 . LEU D 1 121 ? 177.114 154.442 92.350  1.00 126.27 ? 121 LEU D CD1 1 
ATOM   15021 C CD2 . LEU D 1 121 ? 178.503 153.280 94.024  1.00 125.94 ? 121 LEU D CD2 1 
ATOM   15022 N N   . MET D 1 122 ? 175.588 156.394 96.663  1.00 114.28 ? 122 MET D N   1 
ATOM   15023 C CA  . MET D 1 122 ? 174.409 156.094 97.476  1.00 114.83 ? 122 MET D CA  1 
ATOM   15024 C C   . MET D 1 122 ? 173.258 157.061 97.150  1.00 117.83 ? 122 MET D C   1 
ATOM   15025 O O   . MET D 1 122 ? 172.129 156.625 96.940  1.00 114.54 ? 122 MET D O   1 
ATOM   15026 C CB  . MET D 1 122 ? 174.798 156.117 98.957  1.00 116.99 ? 122 MET D CB  1 
ATOM   15027 C CG  . MET D 1 122 ? 175.879 155.078 99.253  1.00 112.92 ? 122 MET D CG  1 
ATOM   15028 S SD  . MET D 1 122 ? 176.400 155.034 100.974 1.00 113.27 ? 122 MET D SD  1 
ATOM   15029 C CE  . MET D 1 122 ? 178.064 154.375 100.760 1.00 113.37 ? 122 MET D CE  1 
ATOM   15030 N N   . LYS D 1 123 ? 173.546 158.362 96.996  1.00 129.75 ? 123 LYS D N   1 
ATOM   15031 C CA  . LYS D 1 123 ? 172.589 159.390 96.550  1.00 128.03 ? 123 LYS D CA  1 
ATOM   15032 C C   . LYS D 1 123 ? 171.978 159.073 95.174  1.00 128.17 ? 123 LYS D C   1 
ATOM   15033 O O   . LYS D 1 123 ? 170.785 159.278 94.977  1.00 128.74 ? 123 LYS D O   1 
ATOM   15034 C CB  . LYS D 1 123 ? 173.300 160.757 96.560  1.00 127.22 ? 123 LYS D CB  1 
ATOM   15035 C CG  . LYS D 1 123 ? 172.364 161.967 96.609  1.00 130.13 ? 123 LYS D CG  1 
ATOM   15036 C CD  . LYS D 1 123 ? 171.708 162.158 97.976  1.00 129.01 ? 123 LYS D CD  1 
ATOM   15037 C CE  . LYS D 1 123 ? 170.902 163.452 98.008  1.00 129.46 ? 123 LYS D CE  1 
ATOM   15038 N NZ  . LYS D 1 123 ? 170.298 163.688 99.335  1.00 128.58 ? 123 LYS D NZ  1 
ATOM   15039 N N   . ALA D 1 124 ? 172.770 158.514 94.253  1.00 121.64 ? 124 ALA D N   1 
ATOM   15040 C CA  . ALA D 1 124 ? 172.322 158.050 92.941  1.00 120.87 ? 124 ALA D CA  1 
ATOM   15041 C C   . ALA D 1 124 ? 171.406 156.819 93.030  1.00 121.28 ? 124 ALA D C   1 
ATOM   15042 O O   . ALA D 1 124 ? 170.328 156.808 92.438  1.00 121.76 ? 124 ALA D O   1 
ATOM   15043 C CB  . ALA D 1 124 ? 173.554 157.749 92.078  1.00 118.81 ? 124 ALA D CB  1 
ATOM   15044 N N   . VAL D 1 125 ? 171.802 155.791 93.786  1.00 117.51 ? 125 VAL D N   1 
ATOM   15045 C CA  . VAL D 1 125 ? 171.042 154.534 93.927  1.00 115.15 ? 125 VAL D CA  1 
ATOM   15046 C C   . VAL D 1 125 ? 169.758 154.706 94.757  1.00 114.04 ? 125 VAL D C   1 
ATOM   15047 O O   . VAL D 1 125 ? 168.793 153.989 94.535  1.00 112.31 ? 125 VAL D O   1 
ATOM   15048 C CB  . VAL D 1 125 ? 171.947 153.419 94.491  1.00 112.88 ? 125 VAL D CB  1 
ATOM   15049 C CG1 . VAL D 1 125 ? 171.214 152.090 94.670  1.00 112.10 ? 125 VAL D CG1 1 
ATOM   15050 C CG2 . VAL D 1 125 ? 173.109 153.106 93.541  1.00 113.46 ? 125 VAL D CG2 1 
ATOM   15051 N N   . LEU D 1 126 ? 169.672 155.691 95.655  1.00 110.74 ? 126 LEU D N   1 
ATOM   15052 C CA  . LEU D 1 126 ? 168.414 156.059 96.322  1.00 109.87 ? 126 LEU D CA  1 
ATOM   15053 C C   . LEU D 1 126 ? 167.359 156.678 95.377  1.00 110.14 ? 126 LEU D C   1 
ATOM   15054 O O   . LEU D 1 126 ? 166.191 156.768 95.743  1.00 107.98 ? 126 LEU D O   1 
ATOM   15055 C CB  . LEU D 1 126 ? 168.735 157.017 97.486  1.00 105.33 ? 126 LEU D CB  1 
ATOM   15056 C CG  . LEU D 1 126 ? 169.392 156.326 98.688  1.00 106.27 ? 126 LEU D CG  1 
ATOM   15057 C CD1 . LEU D 1 126 ? 170.078 157.334 99.600  1.00 107.53 ? 126 LEU D CD1 1 
ATOM   15058 C CD2 . LEU D 1 126 ? 168.364 155.568 99.521  1.00 107.33 ? 126 LEU D CD2 1 
ATOM   15059 N N   . ASN D 1 127 ? 167.748 157.100 94.170  1.00 124.50 ? 127 ASN D N   1 
ATOM   15060 C CA  . ASN D 1 127 ? 166.926 157.850 93.214  1.00 123.54 ? 127 ASN D CA  1 
ATOM   15061 C C   . ASN D 1 127 ? 166.771 157.115 91.866  1.00 125.55 ? 127 ASN D C   1 
ATOM   15062 O O   . ASN D 1 127 ? 166.869 157.714 90.799  1.00 123.84 ? 127 ASN D O   1 
ATOM   15063 C CB  . ASN D 1 127 ? 167.486 159.279 93.099  1.00 123.17 ? 127 ASN D CB  1 
ATOM   15064 C CG  . ASN D 1 127 ? 167.198 160.096 94.343  1.00 125.85 ? 127 ASN D CG  1 
ATOM   15065 O OD1 . ASN D 1 127 ? 166.075 160.510 94.586  1.00 124.45 ? 127 ASN D OD1 1 
ATOM   15066 N ND2 . ASN D 1 127 ? 168.174 160.362 95.171  1.00 124.09 ? 127 ASN D ND2 1 
ATOM   15067 N N   . LEU D 1 128 ? 166.518 155.800 91.883  1.00 132.52 ? 128 LEU D N   1 
ATOM   15068 C CA  . LEU D 1 128 ? 166.221 155.027 90.666  1.00 132.24 ? 128 LEU D CA  1 
ATOM   15069 C C   . LEU D 1 128 ? 164.887 155.460 90.036  1.00 131.85 ? 128 LEU D C   1 
ATOM   15070 O O   . LEU D 1 128 ? 163.909 155.709 90.739  1.00 128.96 ? 128 LEU D O   1 
ATOM   15071 C CB  . LEU D 1 128 ? 166.184 153.511 90.940  1.00 130.45 ? 128 LEU D CB  1 
ATOM   15072 C CG  . LEU D 1 128 ? 167.406 152.908 91.643  1.00 130.22 ? 128 LEU D CG  1 
ATOM   15073 C CD1 . LEU D 1 128 ? 167.282 151.394 91.694  1.00 130.25 ? 128 LEU D CD1 1 
ATOM   15074 C CD2 . LEU D 1 128 ? 168.725 153.243 90.957  1.00 129.16 ? 128 LEU D CD2 1 
ATOM   15075 N N   . GLN D 1 129 ? 164.832 155.506 88.708  1.00 141.99 ? 129 GLN D N   1 
ATOM   15076 C CA  . GLN D 1 129 ? 163.650 155.857 87.917  1.00 141.88 ? 129 GLN D CA  1 
ATOM   15077 C C   . GLN D 1 129 ? 163.258 154.648 87.062  1.00 140.30 ? 129 GLN D C   1 
ATOM   15078 O O   . GLN D 1 129 ? 164.063 154.151 86.277  1.00 138.60 ? 129 GLN D O   1 
ATOM   15079 C CB  . GLN D 1 129 ? 163.966 157.097 87.061  1.00 139.52 ? 129 GLN D CB  1 
ATOM   15080 C CG  . GLN D 1 129 ? 164.273 158.340 87.920  1.00 138.05 ? 129 GLN D CG  1 
ATOM   15081 C CD  . GLN D 1 129 ? 164.863 159.512 87.137  1.00 138.72 ? 129 GLN D CD  1 
ATOM   15082 O OE1 . GLN D 1 129 ? 165.092 159.470 85.938  1.00 139.49 ? 129 GLN D OE1 1 
ATOM   15083 N NE2 . GLN D 1 129 ? 165.142 160.614 87.794  1.00 139.78 ? 129 GLN D NE2 1 
ATOM   15084 N N   . ASP D 1 130 ? 162.043 154.121 87.234  1.00 137.80 ? 130 ASP D N   1 
ATOM   15085 C CA  . ASP D 1 130 ? 161.599 152.897 86.551  1.00 138.01 ? 130 ASP D CA  1 
ATOM   15086 C C   . ASP D 1 130 ? 162.556 151.693 86.713  1.00 138.26 ? 130 ASP D C   1 
ATOM   15087 O O   . ASP D 1 130 ? 162.672 150.849 85.829  1.00 137.58 ? 130 ASP D O   1 
ATOM   15088 C CB  . ASP D 1 130 ? 161.299 153.212 85.084  1.00 136.25 ? 130 ASP D CB  1 
ATOM   15089 N N   . GLY D 1 131 ? 163.262 151.619 87.849  1.00 135.36 ? 131 GLY D N   1 
ATOM   15090 C CA  . GLY D 1 131 ? 164.211 150.552 88.191  1.00 135.09 ? 131 GLY D CA  1 
ATOM   15091 C C   . GLY D 1 131 ? 165.695 150.822 87.907  1.00 135.03 ? 131 GLY D C   1 
ATOM   15092 O O   . GLY D 1 131 ? 166.513 149.980 88.273  1.00 135.96 ? 131 GLY D O   1 
ATOM   15093 N N   . VAL D 1 132 ? 166.082 151.956 87.303  1.00 137.66 ? 132 VAL D N   1 
ATOM   15094 C CA  . VAL D 1 132 ? 167.498 152.292 86.998  1.00 139.14 ? 132 VAL D CA  1 
ATOM   15095 C C   . VAL D 1 132 ? 167.793 153.801 87.095  1.00 138.94 ? 132 VAL D C   1 
ATOM   15096 O O   . VAL D 1 132 ? 166.904 154.623 86.914  1.00 135.51 ? 132 VAL D O   1 
ATOM   15097 C CB  . VAL D 1 132 ? 167.883 151.711 85.620  1.00 137.58 ? 132 VAL D CB  1 
ATOM   15098 C CG1 . VAL D 1 132 ? 167.198 152.413 84.446  1.00 136.89 ? 132 VAL D CG1 1 
ATOM   15099 C CG2 . VAL D 1 132 ? 169.393 151.731 85.374  1.00 134.85 ? 132 VAL D CG2 1 
ATOM   15100 N N   . ASN D 1 133 ? 169.034 154.200 87.394  1.00 140.41 ? 133 ASN D N   1 
ATOM   15101 C CA  . ASN D 1 133 ? 169.495 155.593 87.286  1.00 139.62 ? 133 ASN D CA  1 
ATOM   15102 C C   . ASN D 1 133 ? 170.617 155.690 86.239  1.00 140.53 ? 133 ASN D C   1 
ATOM   15103 O O   . ASN D 1 133 ? 171.677 155.084 86.397  1.00 139.82 ? 133 ASN D O   1 
ATOM   15104 C CB  . ASN D 1 133 ? 169.915 156.103 88.679  1.00 139.92 ? 133 ASN D CB  1 
ATOM   15105 C CG  . ASN D 1 133 ? 170.373 157.555 88.711  1.00 140.80 ? 133 ASN D CG  1 
ATOM   15106 O OD1 . ASN D 1 133 ? 170.753 158.139 87.709  1.00 139.21 ? 133 ASN D OD1 1 
ATOM   15107 N ND2 . ASN D 1 133 ? 170.362 158.180 89.862  1.00 141.10 ? 133 ASN D ND2 1 
ATOM   15108 N N   . ALA D 1 134 ? 170.411 156.481 85.185  1.00 146.12 ? 134 ALA D N   1 
ATOM   15109 C CA  . ALA D 1 134 ? 171.359 156.620 84.079  1.00 145.08 ? 134 ALA D CA  1 
ATOM   15110 C C   . ALA D 1 134 ? 172.713 157.250 84.472  1.00 146.79 ? 134 ALA D C   1 
ATOM   15111 O O   . ALA D 1 134 ? 173.681 157.117 83.726  1.00 147.41 ? 134 ALA D O   1 
ATOM   15112 C CB  . ALA D 1 134 ? 170.671 157.425 82.970  1.00 145.31 ? 134 ALA D CB  1 
ATOM   15113 N N   . CYS D 1 135 ? 172.812 157.914 85.629  1.00 147.40 ? 135 CYS D N   1 
ATOM   15114 C CA  . CYS D 1 135 ? 174.059 158.511 86.110  1.00 147.28 ? 135 CYS D CA  1 
ATOM   15115 C C   . CYS D 1 135 ? 175.067 157.490 86.654  1.00 147.73 ? 135 CYS D C   1 
ATOM   15116 O O   . CYS D 1 135 ? 176.251 157.805 86.707  1.00 146.85 ? 135 CYS D O   1 
ATOM   15117 C CB  . CYS D 1 135 ? 173.758 159.550 87.198  1.00 148.22 ? 135 CYS D CB  1 
ATOM   15118 S SG  . CYS D 1 135 ? 172.611 160.803 86.580  1.00 153.08 ? 135 CYS D SG  1 
ATOM   15119 N N   . ILE D 1 136 ? 174.647 156.291 87.074  1.00 143.94 ? 136 ILE D N   1 
ATOM   15120 C CA  . ILE D 1 136 ? 175.536 155.348 87.781  1.00 142.28 ? 136 ILE D CA  1 
ATOM   15121 C C   . ILE D 1 136 ? 176.701 154.896 86.892  1.00 141.35 ? 136 ILE D C   1 
ATOM   15122 O O   . ILE D 1 136 ? 177.852 154.989 87.302  1.00 142.51 ? 136 ILE D O   1 
ATOM   15123 C CB  . ILE D 1 136 ? 174.744 154.148 88.346  1.00 142.23 ? 136 ILE D CB  1 
ATOM   15124 C CG1 . ILE D 1 136 ? 173.773 154.613 89.451  1.00 141.43 ? 136 ILE D CG1 1 
ATOM   15125 C CG2 . ILE D 1 136 ? 175.696 153.079 88.911  1.00 143.53 ? 136 ILE D CG2 1 
ATOM   15126 C CD1 . ILE D 1 136 ? 172.707 153.567 89.778  1.00 138.36 ? 136 ILE D CD1 1 
ATOM   15127 N N   . MET D 1 137 ? 176.432 154.460 85.658  1.00 146.40 ? 137 MET D N   1 
ATOM   15128 C CA  . MET D 1 137 ? 177.478 154.020 84.730  1.00 147.62 ? 137 MET D CA  1 
ATOM   15129 C C   . MET D 1 137 ? 178.548 155.113 84.468  1.00 147.80 ? 137 MET D C   1 
ATOM   15130 O O   . MET D 1 137 ? 179.726 154.840 84.698  1.00 146.53 ? 137 MET D O   1 
ATOM   15131 C CB  . MET D 1 137 ? 176.828 153.452 83.458  1.00 145.69 ? 137 MET D CB  1 
ATOM   15132 C CG  . MET D 1 137 ? 177.812 152.855 82.447  1.00 146.93 ? 137 MET D CG  1 
ATOM   15133 S SD  . MET D 1 137 ? 178.497 151.231 82.883  1.00 148.85 ? 137 MET D SD  1 
ATOM   15134 C CE  . MET D 1 137 ? 180.102 151.701 83.565  1.00 145.66 ? 137 MET D CE  1 
ATOM   15135 N N   . PRO D 1 138 ? 178.208 156.359 84.075  1.00 149.59 ? 138 PRO D N   1 
ATOM   15136 C CA  . PRO D 1 138 ? 179.210 157.411 83.935  1.00 148.21 ? 138 PRO D CA  1 
ATOM   15137 C C   . PRO D 1 138 ? 179.829 157.848 85.272  1.00 148.44 ? 138 PRO D C   1 
ATOM   15138 O O   . PRO D 1 138 ? 181.026 158.100 85.294  1.00 149.82 ? 138 PRO D O   1 
ATOM   15139 C CB  . PRO D 1 138 ? 178.524 158.562 83.196  1.00 147.27 ? 138 PRO D CB  1 
ATOM   15140 C CG  . PRO D 1 138 ? 177.041 158.338 83.449  1.00 148.03 ? 138 PRO D CG  1 
ATOM   15141 C CD  . PRO D 1 138 ? 176.924 156.823 83.573  1.00 148.93 ? 138 PRO D CD  1 
ATOM   15142 N N   . LEU D 1 139 ? 179.100 157.882 86.393  1.00 142.98 ? 139 LEU D N   1 
ATOM   15143 C CA  . LEU D 1 139 ? 179.685 158.207 87.705  1.00 143.79 ? 139 LEU D CA  1 
ATOM   15144 C C   . LEU D 1 139 ? 180.778 157.198 88.105  1.00 145.49 ? 139 LEU D C   1 
ATOM   15145 O O   . LEU D 1 139 ? 181.849 157.581 88.577  1.00 144.35 ? 139 LEU D O   1 
ATOM   15146 C CB  . LEU D 1 139 ? 178.556 158.266 88.751  1.00 145.17 ? 139 LEU D CB  1 
ATOM   15147 C CG  . LEU D 1 139 ? 178.999 158.677 90.162  1.00 144.61 ? 139 LEU D CG  1 
ATOM   15148 C CD1 . LEU D 1 139 ? 179.362 160.159 90.222  1.00 145.06 ? 139 LEU D CD1 1 
ATOM   15149 C CD2 . LEU D 1 139 ? 177.865 158.420 91.150  1.00 143.86 ? 139 LEU D CD2 1 
ATOM   15150 N N   . LEU D 1 140 ? 180.542 155.907 87.862  1.00 144.75 ? 140 LEU D N   1 
ATOM   15151 C CA  . LEU D 1 140 ? 181.534 154.858 88.078  1.00 143.51 ? 140 LEU D CA  1 
ATOM   15152 C C   . LEU D 1 140 ? 182.712 154.955 87.101  1.00 142.89 ? 140 LEU D C   1 
ATOM   15153 O O   . LEU D 1 140 ? 183.854 154.798 87.524  1.00 141.53 ? 140 LEU D O   1 
ATOM   15154 C CB  . LEU D 1 140 ? 180.848 153.482 88.025  1.00 142.77 ? 140 LEU D CB  1 
ATOM   15155 C CG  . LEU D 1 140 ? 179.883 153.221 89.194  1.00 141.61 ? 140 LEU D CG  1 
ATOM   15156 C CD1 . LEU D 1 140 ? 179.261 151.834 89.059  1.00 140.75 ? 140 LEU D CD1 1 
ATOM   15157 C CD2 . LEU D 1 140 ? 180.597 153.295 90.538  1.00 140.49 ? 140 LEU D CD2 1 
ATOM   15158 N N   . GLN D 1 141 ? 182.462 155.350 85.860  1.00 150.71 ? 141 GLN D N   1 
ATOM   15159 C CA  . GLN D 1 141 ? 183.644 155.573 84.993  1.00 150.64 ? 141 GLN D CA  1 
ATOM   15160 C C   . GLN D 1 141 ? 184.432 156.747 85.582  1.00 149.63 ? 141 GLN D C   1 
ATOM   15161 O O   . GLN D 1 141 ? 185.650 156.596 85.775  1.00 148.30 ? 141 GLN D O   1 
ATOM   15162 C CB  . GLN D 1 141 ? 183.246 155.858 83.549  1.00 149.54 ? 141 GLN D CB  1 
ATOM   15163 C CG  . GLN D 1 141 ? 184.419 155.736 82.588  1.00 149.72 ? 141 GLN D CG  1 
ATOM   15164 C CD  . GLN D 1 141 ? 185.360 154.630 82.999  1.00 150.41 ? 141 GLN D CD  1 
ATOM   15165 O OE1 . GLN D 1 141 ? 185.133 153.458 82.709  1.00 149.60 ? 141 GLN D OE1 1 
ATOM   15166 N NE2 . GLN D 1 141 ? 186.431 154.995 83.683  1.00 150.90 ? 141 GLN D NE2 1 
ATOM   15167 N N   . ILE D 1 142 ? 183.755 157.859 85.881  1.00 153.00 ? 142 ILE D N   1 
ATOM   15168 C CA  . ILE D 1 142 ? 184.437 159.057 86.391  1.00 152.98 ? 142 ILE D CA  1 
ATOM   15169 C C   . ILE D 1 142 ? 185.324 158.714 87.599  1.00 154.53 ? 142 ILE D C   1 
ATOM   15170 O O   . ILE D 1 142 ? 186.471 159.149 87.651  1.00 153.98 ? 142 ILE D O   1 
ATOM   15171 C CB  . ILE D 1 142 ? 183.405 160.164 86.701  1.00 152.92 ? 142 ILE D CB  1 
ATOM   15172 C CG1 . ILE D 1 142 ? 182.820 160.713 85.380  1.00 152.57 ? 142 ILE D CG1 1 
ATOM   15173 C CG2 . ILE D 1 142 ? 184.029 161.309 87.516  1.00 153.69 ? 142 ILE D CG2 1 
ATOM   15174 C CD1 . ILE D 1 142 ? 181.495 161.466 85.530  1.00 153.33 ? 142 ILE D CD1 1 
ATOM   15175 N N   . ASP D 1 143 ? 184.858 157.886 88.537  1.00 154.73 ? 143 ASP D N   1 
ATOM   15176 C CA  . ASP D 1 143 ? 185.697 157.393 89.638  1.00 153.23 ? 143 ASP D CA  1 
ATOM   15177 C C   . ASP D 1 143 ? 186.889 156.562 89.128  1.00 154.47 ? 143 ASP D C   1 
ATOM   15178 O O   . ASP D 1 143 ? 188.033 156.762 89.540  1.00 153.45 ? 143 ASP D O   1 
ATOM   15179 C CB  . ASP D 1 143 ? 184.845 156.548 90.593  1.00 153.44 ? 143 ASP D CB  1 
ATOM   15180 C CG  . ASP D 1 143 ? 185.658 156.079 91.806  1.00 155.55 ? 143 ASP D CG  1 
ATOM   15181 O OD1 . ASP D 1 143 ? 186.263 156.943 92.474  1.00 155.48 ? 143 ASP D OD1 1 
ATOM   15182 O OD2 . ASP D 1 143 ? 185.660 154.862 92.097  1.00 154.75 ? 143 ASP D OD2 1 
ATOM   15183 N N   . LYS D 1 144 ? 186.626 155.652 88.182  1.00 151.74 ? 144 LYS D N   1 
ATOM   15184 C CA  . LYS D 1 144 ? 187.615 154.768 87.549  1.00 150.34 ? 144 LYS D CA  1 
ATOM   15185 C C   . LYS D 1 144 ? 188.684 155.550 86.770  1.00 151.39 ? 144 LYS D C   1 
ATOM   15186 O O   . LYS D 1 144 ? 189.864 155.227 86.854  1.00 151.82 ? 144 LYS D O   1 
ATOM   15187 C CB  . LYS D 1 144 ? 186.825 153.787 86.669  1.00 152.16 ? 144 LYS D CB  1 
ATOM   15188 C CG  . LYS D 1 144 ? 187.595 152.572 86.137  1.00 152.01 ? 144 LYS D CG  1 
ATOM   15189 C CD  . LYS D 1 144 ? 186.711 151.701 85.223  1.00 151.56 ? 144 LYS D CD  1 
ATOM   15190 C CE  . LYS D 1 144 ? 185.470 151.128 85.928  1.00 150.89 ? 144 LYS D CE  1 
ATOM   15191 N NZ  . LYS D 1 144 ? 184.544 150.449 84.991  1.00 149.51 ? 144 LYS D NZ  1 
ATOM   15192 N N   . ASP D 1 145 ? 188.284 156.618 86.078  1.00 157.74 ? 145 ASP D N   1 
ATOM   15193 C CA  . ASP D 1 145 ? 189.175 157.562 85.387  1.00 157.63 ? 145 ASP D CA  1 
ATOM   15194 C C   . ASP D 1 145 ? 189.883 158.543 86.336  1.00 156.89 ? 145 ASP D C   1 
ATOM   15195 O O   . ASP D 1 145 ? 190.942 159.069 85.983  1.00 157.15 ? 145 ASP D O   1 
ATOM   15196 C CB  . ASP D 1 145 ? 188.383 158.352 84.331  1.00 158.64 ? 145 ASP D CB  1 
ATOM   15197 C CG  . ASP D 1 145 ? 187.970 157.535 83.098  1.00 158.71 ? 145 ASP D CG  1 
ATOM   15198 O OD1 . ASP D 1 145 ? 188.520 156.434 82.875  1.00 157.97 ? 145 ASP D OD1 1 
ATOM   15199 O OD2 . ASP D 1 145 ? 187.155 158.039 82.293  1.00 157.87 ? 145 ASP D OD2 1 
ATOM   15200 N N   . SER D 1 146 ? 189.348 158.798 87.535  1.00 158.29 ? 146 SER D N   1 
ATOM   15201 C CA  . SER D 1 146 ? 190.019 159.637 88.536  1.00 158.17 ? 146 SER D CA  1 
ATOM   15202 C C   . SER D 1 146 ? 191.191 158.939 89.243  1.00 158.81 ? 146 SER D C   1 
ATOM   15203 O O   . SER D 1 146 ? 191.972 159.613 89.915  1.00 157.61 ? 146 SER D O   1 
ATOM   15204 C CB  . SER D 1 146 ? 189.007 160.125 89.572  1.00 158.57 ? 146 SER D CB  1 
ATOM   15205 O OG  . SER D 1 146 ? 189.600 161.099 90.405  1.00 159.70 ? 146 SER D OG  1 
ATOM   15206 N N   . GLY D 1 147 ? 191.332 157.613 89.134  1.00 158.88 ? 147 GLY D N   1 
ATOM   15207 C CA  . GLY D 1 147 ? 192.478 156.878 89.693  1.00 158.02 ? 147 GLY D CA  1 
ATOM   15208 C C   . GLY D 1 147 ? 192.405 156.678 91.214  1.00 160.54 ? 147 GLY D C   1 
ATOM   15209 O O   . GLY D 1 147 ? 193.429 156.646 91.899  1.00 160.31 ? 147 GLY D O   1 
ATOM   15210 N N   . ASN D 1 148 ? 191.187 156.563 91.740  1.00 159.29 ? 148 ASN D N   1 
ATOM   15211 C CA  . ASN D 1 148 ? 190.902 156.468 93.166  1.00 158.45 ? 148 ASN D CA  1 
ATOM   15212 C C   . ASN D 1 148 ? 191.489 155.183 93.805  1.00 157.37 ? 148 ASN D C   1 
ATOM   15213 O O   . ASN D 1 148 ? 191.201 154.086 93.319  1.00 155.82 ? 148 ASN D O   1 
ATOM   15214 C CB  . ASN D 1 148 ? 189.373 156.543 93.289  1.00 157.11 ? 148 ASN D CB  1 
ATOM   15215 C CG  . ASN D 1 148 ? 188.867 156.650 94.711  1.00 157.07 ? 148 ASN D CG  1 
ATOM   15216 O OD1 . ASN D 1 148 ? 189.597 156.511 95.679  1.00 156.93 ? 148 ASN D OD1 1 
ATOM   15217 N ND2 . ASN D 1 148 ? 187.599 156.899 94.879  1.00 156.91 ? 148 ASN D ND2 1 
ATOM   15218 N N   . PRO D 1 149 ? 192.258 155.268 94.910  1.00 161.42 ? 149 PRO D N   1 
ATOM   15219 C CA  . PRO D 1 149 ? 192.757 154.097 95.639  1.00 161.62 ? 149 PRO D CA  1 
ATOM   15220 C C   . PRO D 1 149 ? 191.690 153.384 96.498  1.00 161.52 ? 149 PRO D C   1 
ATOM   15221 O O   . PRO D 1 149 ? 191.928 152.267 96.957  1.00 159.60 ? 149 PRO D O   1 
ATOM   15222 C CB  . PRO D 1 149 ? 193.901 154.637 96.507  1.00 161.48 ? 149 PRO D CB  1 
ATOM   15223 C CG  . PRO D 1 149 ? 193.478 156.073 96.792  1.00 160.59 ? 149 PRO D CG  1 
ATOM   15224 C CD  . PRO D 1 149 ? 192.799 156.490 95.490  1.00 161.28 ? 149 PRO D CD  1 
ATOM   15225 N N   . LYS D 1 150 ? 190.527 154.004 96.732  1.00 158.02 ? 150 LYS D N   1 
ATOM   15226 C CA  . LYS D 1 150 ? 189.416 153.492 97.555  1.00 155.96 ? 150 LYS D CA  1 
ATOM   15227 C C   . LYS D 1 150 ? 188.105 153.587 96.770  1.00 155.84 ? 150 LYS D C   1 
ATOM   15228 O O   . LYS D 1 150 ? 187.370 154.566 96.914  1.00 157.75 ? 150 LYS D O   1 
ATOM   15229 C CB  . LYS D 1 150 ? 189.355 154.273 98.883  1.00 155.30 ? 150 LYS D CB  1 
ATOM   15230 C CG  . LYS D 1 150 ? 190.597 154.072 99.760  1.00 155.45 ? 150 LYS D CG  1 
ATOM   15231 C CD  . LYS D 1 150 ? 190.476 154.860 101.066 1.00 156.08 ? 150 LYS D CD  1 
ATOM   15232 C CE  . LYS D 1 150 ? 191.744 154.682 101.901 1.00 156.02 ? 150 LYS D CE  1 
ATOM   15233 N NZ  . LYS D 1 150 ? 191.682 155.448 103.164 1.00 155.32 ? 150 LYS D NZ  1 
ATOM   15234 N N   . LEU D 1 151 ? 187.864 152.606 95.897  1.00 143.35 ? 151 LEU D N   1 
ATOM   15235 C CA  . LEU D 1 151 ? 186.838 152.623 94.842  1.00 144.81 ? 151 LEU D CA  1 
ATOM   15236 C C   . LEU D 1 151 ? 185.428 152.968 95.350  1.00 144.41 ? 151 LEU D C   1 
ATOM   15237 O O   . LEU D 1 151 ? 184.997 152.482 96.395  1.00 143.26 ? 151 LEU D O   1 
ATOM   15238 C CB  . LEU D 1 151 ? 186.800 151.260 94.124  1.00 145.81 ? 151 LEU D CB  1 
ATOM   15239 C CG  . LEU D 1 151 ? 187.931 150.980 93.121  1.00 146.15 ? 151 LEU D CG  1 
ATOM   15240 C CD1 . LEU D 1 151 ? 189.302 150.815 93.771  1.00 145.18 ? 151 LEU D CD1 1 
ATOM   15241 C CD2 . LEU D 1 151 ? 187.618 149.696 92.356  1.00 143.70 ? 151 LEU D CD2 1 
ATOM   15242 N N   . LEU D 1 152 ? 184.675 153.744 94.565  1.00 137.85 ? 152 LEU D N   1 
ATOM   15243 C CA  . LEU D 1 152 ? 183.369 154.294 94.943  1.00 136.04 ? 152 LEU D CA  1 
ATOM   15244 C C   . LEU D 1 152 ? 182.293 153.234 95.239  1.00 137.06 ? 152 LEU D C   1 
ATOM   15245 O O   . LEU D 1 152 ? 181.446 153.446 96.100  1.00 136.54 ? 152 LEU D O   1 
ATOM   15246 C CB  . LEU D 1 152 ? 182.960 155.290 93.845  1.00 134.88 ? 152 LEU D CB  1 
ATOM   15247 C CG  . LEU D 1 152 ? 181.619 156.006 94.040  1.00 134.74 ? 152 LEU D CG  1 
ATOM   15248 C CD1 . LEU D 1 152 ? 181.581 156.847 95.313  1.00 136.00 ? 152 LEU D CD1 1 
ATOM   15249 C CD2 . LEU D 1 152 ? 181.370 156.930 92.855  1.00 136.24 ? 152 LEU D CD2 1 
ATOM   15250 N N   . VAL D 1 153 ? 182.347 152.071 94.584  1.00 126.65 ? 153 VAL D N   1 
ATOM   15251 C CA  . VAL D 1 153 ? 181.451 150.936 94.870  1.00 125.69 ? 153 VAL D CA  1 
ATOM   15252 C C   . VAL D 1 153 ? 181.706 150.273 96.228  1.00 124.44 ? 153 VAL D C   1 
ATOM   15253 O O   . VAL D 1 153 ? 180.782 149.707 96.804  1.00 121.37 ? 153 VAL D O   1 
ATOM   15254 C CB  . VAL D 1 153 ? 181.528 149.854 93.777  1.00 122.44 ? 153 VAL D CB  1 
ATOM   15255 C CG1 . VAL D 1 153 ? 180.797 150.288 92.515  1.00 122.21 ? 153 VAL D CG1 1 
ATOM   15256 C CG2 . VAL D 1 153 ? 182.955 149.456 93.394  1.00 123.10 ? 153 VAL D CG2 1 
ATOM   15257 N N   . ASN D 1 154 ? 182.935 150.349 96.749  1.00 126.90 ? 154 ASN D N   1 
ATOM   15258 C CA  . ASN D 1 154 ? 183.350 149.694 97.996  1.00 124.79 ? 154 ASN D CA  1 
ATOM   15259 C C   . ASN D 1 154 ? 183.404 150.646 99.201  1.00 125.40 ? 154 ASN D C   1 
ATOM   15260 O O   . ASN D 1 154 ? 183.601 150.193 100.330 1.00 124.10 ? 154 ASN D O   1 
ATOM   15261 C CB  . ASN D 1 154 ? 184.689 148.966 97.769  1.00 125.09 ? 154 ASN D CB  1 
ATOM   15262 C CG  . ASN D 1 154 ? 184.597 147.843 96.757  1.00 128.03 ? 154 ASN D CG  1 
ATOM   15263 O OD1 . ASN D 1 154 ? 183.542 147.287 96.508  1.00 127.90 ? 154 ASN D OD1 1 
ATOM   15264 N ND2 . ASN D 1 154 ? 185.688 147.475 96.132  1.00 125.61 ? 154 ASN D ND2 1 
ATOM   15265 N N   . ALA D 1 155 ? 183.222 151.951 98.996  1.00 120.74 ? 155 ALA D N   1 
ATOM   15266 C CA  . ALA D 1 155 ? 183.056 152.917 100.073 1.00 117.07 ? 155 ALA D CA  1 
ATOM   15267 C C   . ALA D 1 155 ? 181.738 152.693 100.828 1.00 116.86 ? 155 ALA D C   1 
ATOM   15268 O O   . ALA D 1 155 ? 180.728 152.285 100.254 1.00 115.10 ? 155 ALA D O   1 
ATOM   15269 C CB  . ALA D 1 155 ? 183.151 154.326 99.496  1.00 117.54 ? 155 ALA D CB  1 
ATOM   15270 N N   . GLN D 1 156 ? 181.754 152.967 102.130 1.00 109.47 ? 156 GLN D N   1 
ATOM   15271 C CA  . GLN D 1 156 ? 180.683 152.624 103.065 1.00 107.57 ? 156 GLN D CA  1 
ATOM   15272 C C   . GLN D 1 156 ? 180.388 153.790 104.019 1.00 109.07 ? 156 GLN D C   1 
ATOM   15273 O O   . GLN D 1 156 ? 181.253 154.627 104.269 1.00 109.42 ? 156 GLN D O   1 
ATOM   15274 C CB  . GLN D 1 156 ? 181.097 151.403 103.897 1.00 106.83 ? 156 GLN D CB  1 
ATOM   15275 C CG  . GLN D 1 156 ? 181.398 150.106 103.126 1.00 109.33 ? 156 GLN D CG  1 
ATOM   15276 C CD  . GLN D 1 156 ? 182.582 149.367 103.746 1.00 109.30 ? 156 GLN D CD  1 
ATOM   15277 O OE1 . GLN D 1 156 ? 182.537 148.905 104.874 1.00 105.67 ? 156 GLN D OE1 1 
ATOM   15278 N NE2 . GLN D 1 156 ? 183.690 149.247 103.051 1.00 109.69 ? 156 GLN D NE2 1 
ATOM   15279 N N   . CYS D 1 157 ? 179.192 153.817 104.610 1.00 104.52 ? 157 CYS D N   1 
ATOM   15280 C CA  . CYS D 1 157 ? 178.896 154.704 105.728 1.00 104.85 ? 157 CYS D CA  1 
ATOM   15281 C C   . CYS D 1 157 ? 179.758 154.350 106.956 1.00 106.96 ? 157 CYS D C   1 
ATOM   15282 O O   . CYS D 1 157 ? 180.187 153.205 107.110 1.00 108.34 ? 157 CYS D O   1 
ATOM   15283 C CB  . CYS D 1 157 ? 177.397 154.639 106.018 1.00 102.25 ? 157 CYS D CB  1 
ATOM   15284 S SG  . CYS D 1 157 ? 176.468 155.200 104.569 1.00 99.88  ? 157 CYS D SG  1 
ATOM   15285 N N   . THR D 1 158 ? 180.034 155.325 107.826 1.00 112.36 ? 158 THR D N   1 
ATOM   15286 C CA  . THR D 1 158 ? 181.082 155.246 108.867 1.00 111.55 ? 158 THR D CA  1 
ATOM   15287 C C   . THR D 1 158 ? 180.609 155.592 110.284 1.00 108.66 ? 158 THR D C   1 
ATOM   15288 O O   . THR D 1 158 ? 181.349 155.380 111.242 1.00 104.49 ? 158 THR D O   1 
ATOM   15289 C CB  . THR D 1 158 ? 182.240 156.188 108.511 1.00 112.21 ? 158 THR D CB  1 
ATOM   15290 O OG1 . THR D 1 158 ? 181.742 157.486 108.299 1.00 114.13 ? 158 THR D OG1 1 
ATOM   15291 C CG2 . THR D 1 158 ? 182.987 155.775 107.256 1.00 108.92 ? 158 THR D CG2 1 
ATOM   15292 N N   . ASP D 1 159 ? 179.404 156.130 110.455 1.00 110.87 ? 159 ASP D N   1 
ATOM   15293 C CA  . ASP D 1 159 ? 178.847 156.498 111.762 1.00 108.99 ? 159 ASP D CA  1 
ATOM   15294 C C   . ASP D 1 159 ? 178.347 155.275 112.548 1.00 107.91 ? 159 ASP D C   1 
ATOM   15295 O O   . ASP D 1 159 ? 178.099 154.216 111.985 1.00 110.10 ? 159 ASP D O   1 
ATOM   15296 C CB  . ASP D 1 159 ? 177.699 157.481 111.547 1.00 109.06 ? 159 ASP D CB  1 
ATOM   15297 C CG  . ASP D 1 159 ? 176.604 156.848 110.693 1.00 113.11 ? 159 ASP D CG  1 
ATOM   15298 O OD1 . ASP D 1 159 ? 176.727 156.915 109.446 1.00 113.61 ? 159 ASP D OD1 1 
ATOM   15299 O OD2 . ASP D 1 159 ? 175.676 156.260 111.290 1.00 114.25 ? 159 ASP D OD2 1 
ATOM   15300 N N   . GLU D 1 160 ? 178.157 155.412 113.859 1.00 103.65 ? 160 GLU D N   1 
ATOM   15301 C CA  . GLU D 1 160 ? 177.829 154.287 114.739 1.00 102.68 ? 160 GLU D CA  1 
ATOM   15302 C C   . GLU D 1 160 ? 176.504 153.576 114.422 1.00 103.79 ? 160 GLU D C   1 
ATOM   15303 O O   . GLU D 1 160 ? 176.330 152.432 114.841 1.00 104.89 ? 160 GLU D O   1 
ATOM   15304 C CB  . GLU D 1 160 ? 177.883 154.737 116.212 1.00 102.33 ? 160 GLU D CB  1 
ATOM   15305 C CG  . GLU D 1 160 ? 176.752 155.663 116.702 1.00 106.11 ? 160 GLU D CG  1 
ATOM   15306 C CD  . GLU D 1 160 ? 176.857 157.135 116.257 1.00 109.91 ? 160 GLU D CD  1 
ATOM   15307 O OE1 . GLU D 1 160 ? 177.892 157.543 115.680 1.00 110.06 ? 160 GLU D OE1 1 
ATOM   15308 O OE2 . GLU D 1 160 ? 175.903 157.899 116.521 1.00 105.25 ? 160 GLU D OE2 1 
ATOM   15309 N N   . PHE D 1 161 ? 175.572 154.197 113.693 1.00 91.18  ? 161 PHE D N   1 
ATOM   15310 C CA  . PHE D 1 161 ? 174.321 153.557 113.288 1.00 91.65  ? 161 PHE D CA  1 
ATOM   15311 C C   . PHE D 1 161 ? 174.430 152.868 111.936 1.00 92.34  ? 161 PHE D C   1 
ATOM   15312 O O   . PHE D 1 161 ? 174.039 151.708 111.836 1.00 91.63  ? 161 PHE D O   1 
ATOM   15313 C CB  . PHE D 1 161 ? 173.172 154.561 113.308 1.00 87.64  ? 161 PHE D CB  1 
ATOM   15314 C CG  . PHE D 1 161 ? 172.655 154.823 114.702 1.00 92.97  ? 161 PHE D CG  1 
ATOM   15315 C CD1 . PHE D 1 161 ? 171.738 153.928 115.278 1.00 93.75  ? 161 PHE D CD1 1 
ATOM   15316 C CD2 . PHE D 1 161 ? 173.091 155.940 115.430 1.00 93.11  ? 161 PHE D CD2 1 
ATOM   15317 C CE1 . PHE D 1 161 ? 171.254 154.152 116.574 1.00 92.63  ? 161 PHE D CE1 1 
ATOM   15318 C CE2 . PHE D 1 161 ? 172.600 156.171 116.726 1.00 94.15  ? 161 PHE D CE2 1 
ATOM   15319 C CZ  . PHE D 1 161 ? 171.679 155.278 117.296 1.00 96.67  ? 161 PHE D CZ  1 
ATOM   15320 N N   . TYR D 1 162 ? 174.983 153.517 110.916 1.00 94.28  ? 162 TYR D N   1 
ATOM   15321 C CA  . TYR D 1 162 ? 174.992 152.985 109.551 1.00 92.67  ? 162 TYR D CA  1 
ATOM   15322 C C   . TYR D 1 162 ? 176.337 152.397 109.108 1.00 95.07  ? 162 TYR D C   1 
ATOM   15323 O O   . TYR D 1 162 ? 176.513 152.123 107.927 1.00 99.54  ? 162 TYR D O   1 
ATOM   15324 C CB  . TYR D 1 162 ? 174.428 154.016 108.564 1.00 90.67  ? 162 TYR D CB  1 
ATOM   15325 C CG  . TYR D 1 162 ? 173.074 154.552 108.988 1.00 91.91  ? 162 TYR D CG  1 
ATOM   15326 C CD1 . TYR D 1 162 ? 171.949 153.706 108.972 1.00 92.59  ? 162 TYR D CD1 1 
ATOM   15327 C CD2 . TYR D 1 162 ? 172.953 155.862 109.482 1.00 91.98  ? 162 TYR D CD2 1 
ATOM   15328 C CE1 . TYR D 1 162 ? 170.720 154.157 109.482 1.00 93.00  ? 162 TYR D CE1 1 
ATOM   15329 C CE2 . TYR D 1 162 ? 171.726 156.312 110.004 1.00 92.47  ? 162 TYR D CE2 1 
ATOM   15330 C CZ  . TYR D 1 162 ? 170.613 155.450 110.022 1.00 90.55  ? 162 TYR D CZ  1 
ATOM   15331 O OH  . TYR D 1 162 ? 169.444 155.858 110.566 1.00 85.47  ? 162 TYR D OH  1 
ATOM   15332 N N   . GLN D 1 163 ? 177.290 152.161 110.013 1.00 100.78 ? 163 GLN D N   1 
ATOM   15333 C CA  . GLN D 1 163 ? 178.622 151.665 109.655 1.00 98.90  ? 163 GLN D CA  1 
ATOM   15334 C C   . GLN D 1 163 ? 178.579 150.458 108.709 1.00 96.90  ? 163 GLN D C   1 
ATOM   15335 O O   . GLN D 1 163 ? 177.847 149.494 108.936 1.00 99.36  ? 163 GLN D O   1 
ATOM   15336 C CB  . GLN D 1 163 ? 179.444 151.343 110.911 1.00 98.73  ? 163 GLN D CB  1 
ATOM   15337 C CG  . GLN D 1 163 ? 180.914 151.064 110.580 1.00 98.27  ? 163 GLN D CG  1 
ATOM   15338 C CD  . GLN D 1 163 ? 181.802 151.032 111.822 1.00 104.39 ? 163 GLN D CD  1 
ATOM   15339 O OE1 . GLN D 1 163 ? 181.352 151.013 112.957 1.00 103.48 ? 163 GLN D OE1 1 
ATOM   15340 N NE2 . GLN D 1 163 ? 183.102 151.009 111.653 1.00 101.68 ? 163 GLN D NE2 1 
ATOM   15341 N N   . GLY D 1 164 ? 179.365 150.504 107.638 1.00 90.97  ? 164 GLY D N   1 
ATOM   15342 C CA  . GLY D 1 164 ? 179.482 149.413 106.673 1.00 90.65  ? 164 GLY D CA  1 
ATOM   15343 C C   . GLY D 1 164 ? 178.353 149.331 105.642 1.00 90.74  ? 164 GLY D C   1 
ATOM   15344 O O   . GLY D 1 164 ? 178.451 148.549 104.700 1.00 94.62  ? 164 GLY D O   1 
ATOM   15345 N N   . HIS D 1 165 ? 177.296 150.133 105.774 1.00 81.84  ? 165 HIS D N   1 
ATOM   15346 C CA  . HIS D 1 165 ? 176.245 150.252 104.758 1.00 79.65  ? 165 HIS D CA  1 
ATOM   15347 C C   . HIS D 1 165 ? 176.817 150.746 103.433 1.00 80.81  ? 165 HIS D C   1 
ATOM   15348 O O   . HIS D 1 165 ? 177.662 151.641 103.421 1.00 89.34  ? 165 HIS D O   1 
ATOM   15349 C CB  . HIS D 1 165 ? 175.174 151.213 105.257 1.00 86.54  ? 165 HIS D CB  1 
ATOM   15350 C CG  . HIS D 1 165 ? 173.995 151.353 104.344 1.00 89.59  ? 165 HIS D CG  1 
ATOM   15351 N ND1 . HIS D 1 165 ? 173.300 150.293 103.779 1.00 88.03  ? 165 HIS D ND1 1 
ATOM   15352 C CD2 . HIS D 1 165 ? 173.369 152.517 104.027 1.00 89.53  ? 165 HIS D CD2 1 
ATOM   15353 C CE1 . HIS D 1 165 ? 172.275 150.842 103.117 1.00 84.91  ? 165 HIS D CE1 1 
ATOM   15354 N NE2 . HIS D 1 165 ? 172.288 152.175 103.254 1.00 83.44  ? 165 HIS D NE2 1 
ATOM   15355 N N   . SER D 1 166 ? 176.378 150.182 102.315 1.00 79.39  ? 166 SER D N   1 
ATOM   15356 C CA  . SER D 1 166 ? 176.971 150.426 100.999 1.00 85.41  ? 166 SER D CA  1 
ATOM   15357 C C   . SER D 1 166 ? 175.912 150.583 99.920  1.00 86.49  ? 166 SER D C   1 
ATOM   15358 O O   . SER D 1 166 ? 174.762 150.180 100.082 1.00 89.31  ? 166 SER D O   1 
ATOM   15359 C CB  . SER D 1 166 ? 177.955 149.309 100.625 1.00 90.27  ? 166 SER D CB  1 
ATOM   15360 O OG  . SER D 1 166 ? 177.286 148.181 100.096 1.00 86.54  ? 166 SER D OG  1 
ATOM   15361 N N   . ALA D 1 167 ? 176.302 151.135 98.775  1.00 92.26  ? 167 ALA D N   1 
ATOM   15362 C CA  . ALA D 1 167 ? 175.408 151.290 97.627  1.00 94.42  ? 167 ALA D CA  1 
ATOM   15363 C C   . ALA D 1 167 ? 174.766 149.965 97.180  1.00 94.30  ? 167 ALA D C   1 
ATOM   15364 O O   . ALA D 1 167 ? 173.620 149.966 96.737  1.00 95.55  ? 167 ALA D O   1 
ATOM   15365 C CB  . ALA D 1 167 ? 176.207 151.930 96.496  1.00 94.13  ? 167 ALA D CB  1 
ATOM   15366 N N   . LEU D 1 168 ? 175.462 148.829 97.318  1.00 89.54  ? 168 LEU D N   1 
ATOM   15367 C CA  . LEU D 1 168 ? 174.913 147.510 96.994  1.00 91.67  ? 168 LEU D CA  1 
ATOM   15368 C C   . LEU D 1 168 ? 173.789 147.099 97.956  1.00 91.84  ? 168 LEU D C   1 
ATOM   15369 O O   . LEU D 1 168 ? 172.751 146.625 97.509  1.00 97.16  ? 168 LEU D O   1 
ATOM   15370 C CB  . LEU D 1 168 ? 176.064 146.490 96.940  1.00 90.57  ? 168 LEU D CB  1 
ATOM   15371 C CG  . LEU D 1 168 ? 175.645 145.045 96.619  1.00 89.02  ? 168 LEU D CG  1 
ATOM   15372 C CD1 . LEU D 1 168 ? 174.953 144.913 95.264  1.00 87.42  ? 168 LEU D CD1 1 
ATOM   15373 C CD2 . LEU D 1 168 ? 176.875 144.149 96.588  1.00 90.92  ? 168 LEU D CD2 1 
ATOM   15374 N N   . HIS D 1 169 ? 173.911 147.360 99.260  1.00 76.73  ? 169 HIS D N   1 
ATOM   15375 C CA  . HIS D 1 169 ? 172.799 147.157 100.193 1.00 76.54  ? 169 HIS D CA  1 
ATOM   15376 C C   . HIS D 1 169 ? 171.603 148.076 99.898  1.00 82.99  ? 169 HIS D C   1 
ATOM   15377 O O   . HIS D 1 169 ? 170.458 147.689 100.125 1.00 83.80  ? 169 HIS D O   1 
ATOM   15378 C CB  . HIS D 1 169 ? 173.259 147.380 101.631 1.00 76.35  ? 169 HIS D CB  1 
ATOM   15379 C CG  . HIS D 1 169 ? 174.390 146.513 102.102 1.00 77.51  ? 169 HIS D CG  1 
ATOM   15380 N ND1 . HIS D 1 169 ? 175.743 146.791 101.938 1.00 80.17  ? 169 HIS D ND1 1 
ATOM   15381 C CD2 . HIS D 1 169 ? 174.257 145.397 102.873 1.00 78.61  ? 169 HIS D CD2 1 
ATOM   15382 C CE1 . HIS D 1 169 ? 176.394 145.841 102.622 1.00 79.00  ? 169 HIS D CE1 1 
ATOM   15383 N NE2 . HIS D 1 169 ? 175.527 144.994 103.191 1.00 80.70  ? 169 HIS D NE2 1 
ATOM   15384 N N   . ILE D 1 170 ? 171.825 149.287 99.379  1.00 91.77  ? 170 ILE D N   1 
ATOM   15385 C CA  . ILE D 1 170 ? 170.734 150.162 98.922  1.00 91.30  ? 170 ILE D CA  1 
ATOM   15386 C C   . ILE D 1 170 ? 170.073 149.566 97.680  1.00 93.97  ? 170 ILE D C   1 
ATOM   15387 O O   . ILE D 1 170 ? 168.852 149.445 97.633  1.00 96.47  ? 170 ILE D O   1 
ATOM   15388 C CB  . ILE D 1 170 ? 171.208 151.607 98.658  1.00 86.38  ? 170 ILE D CB  1 
ATOM   15389 C CG1 . ILE D 1 170 ? 171.849 152.218 99.915  1.00 87.13  ? 170 ILE D CG1 1 
ATOM   15390 C CG2 . ILE D 1 170 ? 170.032 152.490 98.219  1.00 86.64  ? 170 ILE D CG2 1 
ATOM   15391 C CD1 . ILE D 1 170 ? 172.468 153.592 99.688  1.00 89.82  ? 170 ILE D CD1 1 
ATOM   15392 N N   . ALA D 1 171 ? 170.860 149.142 96.694  1.00 89.33  ? 171 ALA D N   1 
ATOM   15393 C CA  . ALA D 1 171 ? 170.357 148.554 95.455  1.00 84.50  ? 171 ALA D CA  1 
ATOM   15394 C C   . ALA D 1 171 ? 169.483 147.316 95.701  1.00 87.18  ? 171 ALA D C   1 
ATOM   15395 O O   . ALA D 1 171 ? 168.451 147.141 95.056  1.00 88.64  ? 171 ALA D O   1 
ATOM   15396 C CB  . ALA D 1 171 ? 171.556 148.211 94.571  1.00 82.21  ? 171 ALA D CB  1 
ATOM   15397 N N   . ILE D 1 172 ? 169.873 146.463 96.646  1.00 87.94  ? 172 ILE D N   1 
ATOM   15398 C CA  . ILE D 1 172 ? 169.106 145.271 96.998  1.00 82.72  ? 172 ILE D CA  1 
ATOM   15399 C C   . ILE D 1 172 ? 167.834 145.647 97.760  1.00 85.10  ? 172 ILE D C   1 
ATOM   15400 O O   . ILE D 1 172 ? 166.774 145.126 97.434  1.00 86.36  ? 172 ILE D O   1 
ATOM   15401 C CB  . ILE D 1 172 ? 169.978 144.265 97.769  1.00 79.10  ? 172 ILE D CB  1 
ATOM   15402 C CG1 . ILE D 1 172 ? 171.155 143.789 96.898  1.00 82.87  ? 172 ILE D CG1 1 
ATOM   15403 C CG2 . ILE D 1 172 ? 169.153 143.041 98.188  1.00 82.80  ? 172 ILE D CG2 1 
ATOM   15404 C CD1 . ILE D 1 172 ? 172.279 143.149 97.691  1.00 81.25  ? 172 ILE D CD1 1 
ATOM   15405 N N   . GLU D 1 173 ? 167.866 146.566 98.728  1.00 92.57  ? 173 GLU D N   1 
ATOM   15406 C CA  . GLU D 1 173 ? 166.643 146.950 99.450  1.00 90.29  ? 173 GLU D CA  1 
ATOM   15407 C C   . GLU D 1 173 ? 165.628 147.661 98.551  1.00 93.68  ? 173 GLU D C   1 
ATOM   15408 O O   . GLU D 1 173 ? 164.434 147.383 98.642  1.00 95.59  ? 173 GLU D O   1 
ATOM   15409 C CB  . GLU D 1 173 ? 166.985 147.801 100.675 1.00 92.49  ? 173 GLU D CB  1 
ATOM   15410 C CG  . GLU D 1 173 ? 165.761 148.087 101.566 1.00 95.30  ? 173 GLU D CG  1 
ATOM   15411 C CD  . GLU D 1 173 ? 164.865 149.263 101.120 1.00 100.14 ? 173 GLU D CD  1 
ATOM   15412 O OE1 . GLU D 1 173 ? 165.322 150.172 100.389 1.00 100.32 ? 173 GLU D OE1 1 
ATOM   15413 O OE2 . GLU D 1 173 ? 163.691 149.297 101.555 1.00 97.34  ? 173 GLU D OE2 1 
ATOM   15414 N N   . LYS D 1 174 ? 166.094 148.499 97.620  1.00 97.20  ? 174 LYS D N   1 
ATOM   15415 C CA  . LYS D 1 174 ? 165.291 149.121 96.550  1.00 95.22  ? 174 LYS D CA  1 
ATOM   15416 C C   . LYS D 1 174 ? 164.825 148.125 95.471  1.00 98.04  ? 174 LYS D C   1 
ATOM   15417 O O   . LYS D 1 174 ? 164.150 148.525 94.525  1.00 95.82  ? 174 LYS D O   1 
ATOM   15418 C CB  . LYS D 1 174 ? 166.086 150.299 95.957  1.00 94.13  ? 174 LYS D CB  1 
ATOM   15419 C CG  . LYS D 1 174 ? 166.276 151.457 96.953  1.00 97.35  ? 174 LYS D CG  1 
ATOM   15420 C CD  . LYS D 1 174 ? 164.999 152.281 97.152  1.00 99.27  ? 174 LYS D CD  1 
ATOM   15421 C CE  . LYS D 1 174 ? 165.117 153.268 98.319  1.00 99.54  ? 174 LYS D CE  1 
ATOM   15422 N NZ  . LYS D 1 174 ? 164.625 152.696 99.595  1.00 95.09  ? 174 LYS D NZ  1 
ATOM   15423 N N   . ARG D 1 175 ? 165.150 146.833 95.593  1.00 96.20  ? 175 ARG D N   1 
ATOM   15424 C CA  . ARG D 1 175 ? 164.724 145.709 94.732  1.00 90.42  ? 175 ARG D CA  1 
ATOM   15425 C C   . ARG D 1 175 ? 165.152 145.776 93.260  1.00 91.77  ? 175 ARG D C   1 
ATOM   15426 O O   . ARG D 1 175 ? 164.519 145.151 92.409  1.00 92.66  ? 175 ARG D O   1 
ATOM   15427 C CB  . ARG D 1 175 ? 163.216 145.422 94.874  1.00 93.04  ? 175 ARG D CB  1 
ATOM   15428 C CG  . ARG D 1 175 ? 162.740 145.246 96.315  1.00 92.08  ? 175 ARG D CG  1 
ATOM   15429 C CD  . ARG D 1 175 ? 161.248 144.898 96.370  1.00 91.61  ? 175 ARG D CD  1 
ATOM   15430 N NE  . ARG D 1 175 ? 160.952 143.548 95.850  1.00 99.96  ? 175 ARG D NE  1 
ATOM   15431 C CZ  . ARG D 1 175 ? 161.056 142.409 96.504  1.00 97.15  ? 175 ARG D CZ  1 
ATOM   15432 N NH1 . ARG D 1 175 ? 160.702 141.291 95.947  1.00 91.31  ? 175 ARG D NH1 1 
ATOM   15433 N NH2 . ARG D 1 175 ? 161.514 142.371 97.717  1.00 92.60  ? 175 ARG D NH2 1 
ATOM   15434 N N   . SER D 1 176 ? 166.201 146.522 92.919  1.00 106.64 ? 176 SER D N   1 
ATOM   15435 C CA  . SER D 1 176 ? 166.646 146.642 91.524  1.00 108.42 ? 176 SER D CA  1 
ATOM   15436 C C   . SER D 1 176 ? 167.721 145.616 91.175  1.00 107.17 ? 176 SER D C   1 
ATOM   15437 O O   . SER D 1 176 ? 168.911 145.838 91.399  1.00 108.10 ? 176 SER D O   1 
ATOM   15438 C CB  . SER D 1 176 ? 167.110 148.063 91.214  1.00 108.72 ? 176 SER D CB  1 
ATOM   15439 O OG  . SER D 1 176 ? 167.579 148.112 89.877  1.00 109.80 ? 176 SER D OG  1 
ATOM   15440 N N   . LEU D 1 177 ? 167.324 144.505 90.549  1.00 108.37 ? 177 LEU D N   1 
ATOM   15441 C CA  . LEU D 1 177 ? 168.274 143.554 89.966  1.00 111.60 ? 177 LEU D CA  1 
ATOM   15442 C C   . LEU D 1 177 ? 169.170 144.233 88.922  1.00 110.50 ? 177 LEU D C   1 
ATOM   15443 O O   . LEU D 1 177 ? 170.360 143.947 88.852  1.00 112.12 ? 177 LEU D O   1 
ATOM   15444 C CB  . LEU D 1 177 ? 167.500 142.372 89.357  1.00 112.46 ? 177 LEU D CB  1 
ATOM   15445 C CG  . LEU D 1 177 ? 168.387 141.340 88.633  1.00 109.51 ? 177 LEU D CG  1 
ATOM   15446 C CD1 . LEU D 1 177 ? 169.338 140.622 89.587  1.00 108.01 ? 177 LEU D CD1 1 
ATOM   15447 C CD2 . LEU D 1 177 ? 167.515 140.292 87.951  1.00 107.01 ? 177 LEU D CD2 1 
ATOM   15448 N N   . GLN D 1 178 ? 168.625 145.167 88.137  1.00 114.56 ? 178 GLN D N   1 
ATOM   15449 C CA  . GLN D 1 178 ? 169.378 145.918 87.133  1.00 114.35 ? 178 GLN D CA  1 
ATOM   15450 C C   . GLN D 1 178 ? 170.513 146.735 87.767  1.00 113.36 ? 178 GLN D C   1 
ATOM   15451 O O   . GLN D 1 178 ? 171.623 146.766 87.236  1.00 112.43 ? 178 GLN D O   1 
ATOM   15452 C CB  . GLN D 1 178 ? 168.427 146.848 86.357  1.00 113.21 ? 178 GLN D CB  1 
ATOM   15453 C CG  . GLN D 1 178 ? 167.494 146.129 85.367  1.00 114.33 ? 178 GLN D CG  1 
ATOM   15454 C CD  . GLN D 1 178 ? 166.326 145.366 85.986  1.00 114.82 ? 178 GLN D CD  1 
ATOM   15455 O OE1 . GLN D 1 178 ? 165.970 145.516 87.148  1.00 113.79 ? 178 GLN D OE1 1 
ATOM   15456 N NE2 . GLN D 1 178 ? 165.679 144.508 85.236  1.00 113.85 ? 178 GLN D NE2 1 
ATOM   15457 N N   . CYS D 1 179 ? 170.271 147.353 88.922  1.00 111.40 ? 179 CYS D N   1 
ATOM   15458 C CA  . CYS D 1 179 ? 171.295 148.099 89.635  1.00 110.65 ? 179 CYS D CA  1 
ATOM   15459 C C   . CYS D 1 179 ? 172.290 147.171 90.358  1.00 113.97 ? 179 CYS D C   1 
ATOM   15460 O O   . CYS D 1 179 ? 173.493 147.423 90.307  1.00 112.97 ? 179 CYS D O   1 
ATOM   15461 C CB  . CYS D 1 179 ? 170.596 149.089 90.566  1.00 112.86 ? 179 CYS D CB  1 
ATOM   15462 S SG  . CYS D 1 179 ? 171.810 150.296 91.135  1.00 122.79 ? 179 CYS D SG  1 
ATOM   15463 N N   . VAL D 1 180 ? 171.839 146.052 90.943  1.00 106.09 ? 180 VAL D N   1 
ATOM   15464 C CA  . VAL D 1 180 ? 172.743 145.037 91.520  1.00 104.52 ? 180 VAL D CA  1 
ATOM   15465 C C   . VAL D 1 180 ? 173.731 144.523 90.478  1.00 105.26 ? 180 VAL D C   1 
ATOM   15466 O O   . VAL D 1 180 ? 174.936 144.537 90.713  1.00 103.82 ? 180 VAL D O   1 
ATOM   15467 C CB  . VAL D 1 180 ? 171.957 143.873 92.139  1.00 102.29 ? 180 VAL D CB  1 
ATOM   15468 C CG1 . VAL D 1 180 ? 172.856 142.693 92.508  1.00 105.33 ? 180 VAL D CG1 1 
ATOM   15469 C CG2 . VAL D 1 180 ? 171.260 144.332 93.413  1.00 101.61 ? 180 VAL D CG2 1 
ATOM   15470 N N   . LYS D 1 181 ? 173.238 144.137 89.299  1.00 111.00 ? 181 LYS D N   1 
ATOM   15471 C CA  . LYS D 1 181 ? 174.079 143.756 88.162  1.00 107.80 ? 181 LYS D CA  1 
ATOM   15472 C C   . LYS D 1 181 ? 175.078 144.861 87.813  1.00 111.09 ? 181 LYS D C   1 
ATOM   15473 O O   . LYS D 1 181 ? 176.271 144.601 87.763  1.00 110.43 ? 181 LYS D O   1 
ATOM   15474 C CB  . LYS D 1 181 ? 173.200 143.430 86.946  1.00 105.16 ? 181 LYS D CB  1 
ATOM   15475 C CG  . LYS D 1 181 ? 172.474 142.091 87.101  1.00 110.28 ? 181 LYS D CG  1 
ATOM   15476 C CD  . LYS D 1 181 ? 171.573 141.814 85.896  1.00 111.07 ? 181 LYS D CD  1 
ATOM   15477 C CE  . LYS D 1 181 ? 171.003 140.398 85.965  1.00 111.96 ? 181 LYS D CE  1 
ATOM   15478 N NZ  . LYS D 1 181 ? 170.232 140.068 84.746  1.00 108.69 ? 181 LYS D NZ  1 
ATOM   15479 N N   . LEU D 1 182 ? 174.627 146.098 87.600  1.00 117.54 ? 182 LEU D N   1 
ATOM   15480 C CA  . LEU D 1 182 ? 175.505 147.209 87.226  1.00 114.53 ? 182 LEU D CA  1 
ATOM   15481 C C   . LEU D 1 182 ? 176.625 147.466 88.255  1.00 116.08 ? 182 LEU D C   1 
ATOM   15482 O O   . LEU D 1 182 ? 177.768 147.731 87.879  1.00 116.84 ? 182 LEU D O   1 
ATOM   15483 C CB  . LEU D 1 182 ? 174.619 148.450 87.007  1.00 116.23 ? 182 LEU D CB  1 
ATOM   15484 C CG  . LEU D 1 182 ? 175.370 149.734 86.623  1.00 117.58 ? 182 LEU D CG  1 
ATOM   15485 C CD1 . LEU D 1 182 ? 176.135 149.596 85.312  1.00 116.56 ? 182 LEU D CD1 1 
ATOM   15486 C CD2 . LEU D 1 182 ? 174.367 150.870 86.453  1.00 115.41 ? 182 LEU D CD2 1 
ATOM   15487 N N   . LEU D 1 183 ? 176.320 147.376 89.549  1.00 108.77 ? 183 LEU D N   1 
ATOM   15488 C CA  . LEU D 1 183 ? 177.298 147.535 90.625  1.00 110.13 ? 183 LEU D CA  1 
ATOM   15489 C C   . LEU D 1 183 ? 178.301 146.374 90.676  1.00 111.60 ? 183 LEU D C   1 
ATOM   15490 O O   . LEU D 1 183 ? 179.508 146.608 90.728  1.00 108.26 ? 183 LEU D O   1 
ATOM   15491 C CB  . LEU D 1 183 ? 176.551 147.659 91.965  1.00 110.15 ? 183 LEU D CB  1 
ATOM   15492 C CG  . LEU D 1 183 ? 175.779 148.974 92.152  1.00 106.70 ? 183 LEU D CG  1 
ATOM   15493 C CD1 . LEU D 1 183 ? 174.886 148.859 93.380  1.00 106.17 ? 183 LEU D CD1 1 
ATOM   15494 C CD2 . LEU D 1 183 ? 176.726 150.150 92.372  1.00 110.44 ? 183 LEU D CD2 1 
ATOM   15495 N N   . VAL D 1 184 ? 177.824 145.127 90.648  1.00 115.57 ? 184 VAL D N   1 
ATOM   15496 C CA  . VAL D 1 184 ? 178.680 143.930 90.718  1.00 112.66 ? 184 VAL D CA  1 
ATOM   15497 C C   . VAL D 1 184 ? 179.545 143.773 89.462  1.00 112.23 ? 184 VAL D C   1 
ATOM   15498 O O   . VAL D 1 184 ? 180.726 143.445 89.572  1.00 113.04 ? 184 VAL D O   1 
ATOM   15499 C CB  . VAL D 1 184 ? 177.824 142.681 90.989  1.00 109.50 ? 184 VAL D CB  1 
ATOM   15500 C CG1 . VAL D 1 184 ? 178.624 141.381 90.890  1.00 111.27 ? 184 VAL D CG1 1 
ATOM   15501 C CG2 . VAL D 1 184 ? 177.223 142.725 92.397  1.00 111.41 ? 184 VAL D CG2 1 
ATOM   15502 N N   . GLU D 1 185 ? 179.025 144.093 88.275  1.00 113.59 ? 185 GLU D N   1 
ATOM   15503 C CA  . GLU D 1 185 ? 179.810 144.154 87.030  1.00 114.89 ? 185 GLU D CA  1 
ATOM   15504 C C   . GLU D 1 185 ? 180.963 145.167 87.108  1.00 118.09 ? 185 GLU D C   1 
ATOM   15505 O O   . GLU D 1 185 ? 182.029 144.937 86.541  1.00 119.45 ? 185 GLU D O   1 
ATOM   15506 C CB  . GLU D 1 185 ? 178.892 144.526 85.855  1.00 115.29 ? 185 GLU D CB  1 
ATOM   15507 C CG  . GLU D 1 185 ? 178.009 143.351 85.409  1.00 117.19 ? 185 GLU D CG  1 
ATOM   15508 C CD  . GLU D 1 185 ? 176.880 143.743 84.437  1.00 119.55 ? 185 GLU D CD  1 
ATOM   15509 O OE1 . GLU D 1 185 ? 176.888 144.862 83.877  1.00 119.23 ? 185 GLU D OE1 1 
ATOM   15510 O OE2 . GLU D 1 185 ? 175.999 142.893 84.178  1.00 118.53 ? 185 GLU D OE2 1 
ATOM   15511 N N   . ASN D 1 186 ? 180.787 146.273 87.834  1.00 121.38 ? 186 ASN D N   1 
ATOM   15512 C CA  . ASN D 1 186 ? 181.840 147.258 88.099  1.00 120.53 ? 186 ASN D CA  1 
ATOM   15513 C C   . ASN D 1 186 ? 182.685 146.955 89.351  1.00 120.44 ? 186 ASN D C   1 
ATOM   15514 O O   . ASN D 1 186 ? 183.498 147.783 89.764  1.00 117.17 ? 186 ASN D O   1 
ATOM   15515 C CB  . ASN D 1 186 ? 181.216 148.658 88.088  1.00 120.06 ? 186 ASN D CB  1 
ATOM   15516 C CG  . ASN D 1 186 ? 180.958 149.104 86.664  1.00 122.07 ? 186 ASN D CG  1 
ATOM   15517 O OD1 . ASN D 1 186 ? 181.860 149.564 85.974  1.00 124.20 ? 186 ASN D OD1 1 
ATOM   15518 N ND2 . ASN D 1 186 ? 179.749 148.959 86.179  1.00 121.19 ? 186 ASN D ND2 1 
ATOM   15519 N N   . GLY D 1 187 ? 182.551 145.761 89.933  1.00 117.40 ? 187 GLY D N   1 
ATOM   15520 C CA  . GLY D 1 187 ? 183.424 145.276 91.007  1.00 115.80 ? 187 GLY D CA  1 
ATOM   15521 C C   . GLY D 1 187 ? 182.990 145.623 92.433  1.00 116.56 ? 187 GLY D C   1 
ATOM   15522 O O   . GLY D 1 187 ? 183.835 145.617 93.327  1.00 113.65 ? 187 GLY D O   1 
ATOM   15523 N N   . ALA D 1 188 ? 181.709 145.922 92.662  1.00 115.74 ? 188 ALA D N   1 
ATOM   15524 C CA  . ALA D 1 188 ? 181.176 146.099 94.011  1.00 116.09 ? 188 ALA D CA  1 
ATOM   15525 C C   . ALA D 1 188 ? 181.350 144.827 94.849  1.00 114.51 ? 188 ALA D C   1 
ATOM   15526 O O   . ALA D 1 188 ? 180.881 143.760 94.457  1.00 115.47 ? 188 ALA D O   1 
ATOM   15527 C CB  . ALA D 1 188 ? 179.696 146.480 93.929  1.00 116.02 ? 188 ALA D CB  1 
ATOM   15528 N N   . ASP D 1 189 ? 182.020 144.929 95.994  1.00 112.26 ? 189 ASP D N   1 
ATOM   15529 C CA  . ASP D 1 189 ? 182.318 143.779 96.841  1.00 112.03 ? 189 ASP D CA  1 
ATOM   15530 C C   . ASP D 1 189 ? 181.041 143.185 97.455  1.00 114.47 ? 189 ASP D C   1 
ATOM   15531 O O   . ASP D 1 189 ? 180.374 143.788 98.294  1.00 113.04 ? 189 ASP D O   1 
ATOM   15532 C CB  . ASP D 1 189 ? 183.371 144.151 97.891  1.00 110.14 ? 189 ASP D CB  1 
ATOM   15533 C CG  . ASP D 1 189 ? 183.732 142.995 98.838  1.00 113.47 ? 189 ASP D CG  1 
ATOM   15534 O OD1 . ASP D 1 189 ? 183.361 141.832 98.561  1.00 115.63 ? 189 ASP D OD1 1 
ATOM   15535 O OD2 . ASP D 1 189 ? 184.440 143.255 99.834  1.00 113.24 ? 189 ASP D OD2 1 
ATOM   15536 N N   . VAL D 1 190 ? 180.704 141.970 97.041  1.00 104.43 ? 190 VAL D N   1 
ATOM   15537 C CA  . VAL D 1 190 ? 179.520 141.227 97.472  1.00 99.99  ? 190 VAL D CA  1 
ATOM   15538 C C   . VAL D 1 190 ? 179.576 140.820 98.952  1.00 101.91 ? 190 VAL D C   1 
ATOM   15539 O O   . VAL D 1 190 ? 178.554 140.433 99.509  1.00 102.62 ? 190 VAL D O   1 
ATOM   15540 C CB  . VAL D 1 190 ? 179.337 140.030 96.518  1.00 99.69  ? 190 VAL D CB  1 
ATOM   15541 C CG1 . VAL D 1 190 ? 178.279 139.024 96.945  1.00 106.26 ? 190 VAL D CG1 1 
ATOM   15542 C CG2 . VAL D 1 190 ? 178.938 140.520 95.125  1.00 100.31 ? 190 VAL D CG2 1 
ATOM   15543 N N   . HIS D 1 191 ? 180.726 140.933 99.629  1.00 100.19 ? 191 HIS D N   1 
ATOM   15544 C CA  . HIS D 1 191 ? 180.899 140.519 101.027 1.00 97.99  ? 191 HIS D CA  1 
ATOM   15545 C C   . HIS D 1 191 ? 181.053 141.680 102.023 1.00 100.82 ? 191 HIS D C   1 
ATOM   15546 O O   . HIS D 1 191 ? 181.507 141.475 103.149 1.00 102.76 ? 191 HIS D O   1 
ATOM   15547 C CB  . HIS D 1 191 ? 182.032 139.489 101.148 1.00 102.28 ? 191 HIS D CB  1 
ATOM   15548 C CG  . HIS D 1 191 ? 181.824 138.252 100.313 1.00 105.24 ? 191 HIS D CG  1 
ATOM   15549 N ND1 . HIS D 1 191 ? 182.244 138.066 99.020  1.00 105.96 ? 191 HIS D ND1 1 
ATOM   15550 C CD2 . HIS D 1 191 ? 181.122 137.140 100.674 1.00 98.80  ? 191 HIS D CD2 1 
ATOM   15551 C CE1 . HIS D 1 191 ? 181.828 136.859 98.614  1.00 103.63 ? 191 HIS D CE1 1 
ATOM   15552 N NE2 . HIS D 1 191 ? 181.135 136.256 99.593  1.00 104.39 ? 191 HIS D NE2 1 
ATOM   15553 N N   . LEU D 1 192 ? 180.669 142.902 101.651 1.00 104.66 ? 192 LEU D N   1 
ATOM   15554 C CA  . LEU D 1 192 ? 180.629 144.054 102.561 1.00 99.15  ? 192 LEU D CA  1 
ATOM   15555 C C   . LEU D 1 192 ? 179.586 143.851 103.662 1.00 98.29  ? 192 LEU D C   1 
ATOM   15556 O O   . LEU D 1 192 ? 178.439 143.522 103.382 1.00 101.86 ? 192 LEU D O   1 
ATOM   15557 C CB  . LEU D 1 192 ? 180.300 145.332 101.769 1.00 99.90  ? 192 LEU D CB  1 
ATOM   15558 C CG  . LEU D 1 192 ? 181.383 145.741 100.771 1.00 103.85 ? 192 LEU D CG  1 
ATOM   15559 C CD1 . LEU D 1 192 ? 180.876 146.875 99.892  1.00 105.74 ? 192 LEU D CD1 1 
ATOM   15560 C CD2 . LEU D 1 192 ? 182.659 146.196 101.465 1.00 101.18 ? 192 LEU D CD2 1 
ATOM   15561 N N   . ARG D 1 193 ? 179.949 144.099 104.920 1.00 86.62  ? 193 ARG D N   1 
ATOM   15562 C CA  . ARG D 1 193 ? 179.055 143.923 106.069 1.00 87.74  ? 193 ARG D CA  1 
ATOM   15563 C C   . ARG D 1 193 ? 178.479 145.253 106.546 1.00 88.41  ? 193 ARG D C   1 
ATOM   15564 O O   . ARG D 1 193 ? 179.191 146.058 107.139 1.00 91.00  ? 193 ARG D O   1 
ATOM   15565 C CB  . ARG D 1 193 ? 179.781 143.127 107.155 1.00 88.57  ? 193 ARG D CB  1 
ATOM   15566 C CG  . ARG D 1 193 ? 179.839 141.636 106.865 1.00 91.53  ? 193 ARG D CG  1 
ATOM   15567 C CD  . ARG D 1 193 ? 181.178 140.991 107.144 1.00 91.76  ? 193 ARG D CD  1 
ATOM   15568 N NE  . ARG D 1 193 ? 181.534 141.055 108.550 1.00 98.65  ? 193 ARG D NE  1 
ATOM   15569 C CZ  . ARG D 1 193 ? 182.333 140.186 109.153 1.00 97.01  ? 193 ARG D CZ  1 
ATOM   15570 N NH1 . ARG D 1 193 ? 182.607 140.319 110.438 1.00 91.91  ? 193 ARG D NH1 1 
ATOM   15571 N NH2 . ARG D 1 193 ? 182.840 139.175 108.472 1.00 95.13  ? 193 ARG D NH2 1 
ATOM   15572 N N   . ALA D 1 194 ? 177.177 145.444 106.382 1.00 74.14  ? 194 ALA D N   1 
ATOM   15573 C CA  . ALA D 1 194 ? 176.424 146.520 107.008 1.00 72.72  ? 194 ALA D CA  1 
ATOM   15574 C C   . ALA D 1 194 ? 176.251 146.207 108.497 1.00 71.98  ? 194 ALA D C   1 
ATOM   15575 O O   . ALA D 1 194 ? 175.350 145.476 108.874 1.00 75.09  ? 194 ALA D O   1 
ATOM   15576 C CB  . ALA D 1 194 ? 175.088 146.642 106.277 1.00 76.24  ? 194 ALA D CB  1 
ATOM   15577 N N   . CYS D 1 195 ? 177.154 146.705 109.341 1.00 78.08  ? 195 CYS D N   1 
ATOM   15578 C CA  . CYS D 1 195 ? 177.371 146.210 110.704 1.00 79.85  ? 195 CYS D CA  1 
ATOM   15579 C C   . CYS D 1 195 ? 177.126 147.236 111.818 1.00 85.23  ? 195 CYS D C   1 
ATOM   15580 O O   . CYS D 1 195 ? 177.159 146.868 112.995 1.00 86.75  ? 195 CYS D O   1 
ATOM   15581 C CB  . CYS D 1 195 ? 178.789 145.630 110.782 1.00 83.99  ? 195 CYS D CB  1 
ATOM   15582 S SG  . CYS D 1 195 ? 180.048 146.812 110.223 1.00 87.60  ? 195 CYS D SG  1 
ATOM   15583 N N   . GLY D 1 196 ? 176.868 148.504 111.488 1.00 85.43  ? 196 GLY D N   1 
ATOM   15584 C CA  . GLY D 1 196 ? 176.505 149.541 112.454 1.00 79.17  ? 196 GLY D CA  1 
ATOM   15585 C C   . GLY D 1 196 ? 175.202 149.260 113.202 1.00 78.37  ? 196 GLY D C   1 
ATOM   15586 O O   . GLY D 1 196 ? 174.421 148.393 112.825 1.00 83.83  ? 196 GLY D O   1 
ATOM   15587 N N   . ARG D 1 197 ? 174.958 149.938 114.322 1.00 76.60  ? 197 ARG D N   1 
ATOM   15588 C CA  . ARG D 1 197 ? 173.831 149.609 115.248 1.00 77.20  ? 197 ARG D CA  1 
ATOM   15589 C C   . ARG D 1 197 ? 172.448 149.554 114.620 1.00 79.26  ? 197 ARG D C   1 
ATOM   15590 O O   . ARG D 1 197 ? 171.581 148.921 115.209 1.00 80.43  ? 197 ARG D O   1 
ATOM   15591 C CB  . ARG D 1 197 ? 173.794 150.616 116.396 1.00 77.59  ? 197 ARG D CB  1 
ATOM   15592 C CG  . ARG D 1 197 ? 172.950 150.192 117.587 1.00 81.56  ? 197 ARG D CG  1 
ATOM   15593 C CD  . ARG D 1 197 ? 173.785 149.495 118.639 1.00 80.78  ? 197 ARG D CD  1 
ATOM   15594 N NE  . ARG D 1 197 ? 173.438 148.088 118.746 1.00 87.10  ? 197 ARG D NE  1 
ATOM   15595 C CZ  . ARG D 1 197 ? 172.670 147.578 119.698 1.00 88.84  ? 197 ARG D CZ  1 
ATOM   15596 N NH1 . ARG D 1 197 ? 172.409 146.283 119.713 1.00 84.41  ? 197 ARG D NH1 1 
ATOM   15597 N NH2 . ARG D 1 197 ? 172.166 148.364 120.631 1.00 82.27  ? 197 ARG D NH2 1 
ATOM   15598 N N   . PHE D 1 198 ? 172.209 150.260 113.538 1.00 72.37  ? 198 PHE D N   1 
ATOM   15599 C CA  . PHE D 1 198 ? 170.910 150.120 112.881 1.00 72.09  ? 198 PHE D CA  1 
ATOM   15600 C C   . PHE D 1 198 ? 170.665 148.696 112.350 1.00 75.16  ? 198 PHE D C   1 
ATOM   15601 O O   . PHE D 1 198 ? 169.536 148.223 112.325 1.00 75.17  ? 198 PHE D O   1 
ATOM   15602 C CB  . PHE D 1 198 ? 170.825 151.152 111.756 1.00 68.52  ? 198 PHE D CB  1 
ATOM   15603 C CG  . PHE D 1 198 ? 169.555 151.063 110.948 1.00 72.76  ? 198 PHE D CG  1 
ATOM   15604 C CD1 . PHE D 1 198 ? 168.311 151.296 111.550 1.00 71.94  ? 198 PHE D CD1 1 
ATOM   15605 C CD2 . PHE D 1 198 ? 169.613 150.721 109.592 1.00 73.86  ? 198 PHE D CD2 1 
ATOM   15606 C CE1 . PHE D 1 198 ? 167.138 151.173 110.798 1.00 68.07  ? 198 PHE D CE1 1 
ATOM   15607 C CE2 . PHE D 1 198 ? 168.439 150.584 108.841 1.00 67.66  ? 198 PHE D CE2 1 
ATOM   15608 C CZ  . PHE D 1 198 ? 167.199 150.813 109.444 1.00 64.11  ? 198 PHE D CZ  1 
ATOM   15609 N N   . PHE D 1 199 ? 171.724 147.990 111.956 1.00 65.23  ? 199 PHE D N   1 
ATOM   15610 C CA  . PHE D 1 199 ? 171.670 146.655 111.366 1.00 59.33  ? 199 PHE D CA  1 
ATOM   15611 C C   . PHE D 1 199 ? 171.857 145.520 112.370 1.00 68.95  ? 199 PHE D C   1 
ATOM   15612 O O   . PHE D 1 199 ? 171.728 144.356 112.015 1.00 72.32  ? 199 PHE D O   1 
ATOM   15613 C CB  . PHE D 1 199 ? 172.745 146.563 110.296 1.00 62.27  ? 199 PHE D CB  1 
ATOM   15614 C CG  . PHE D 1 199 ? 172.674 147.681 109.293 1.00 65.12  ? 199 PHE D CG  1 
ATOM   15615 C CD1 . PHE D 1 199 ? 171.577 147.778 108.428 1.00 67.91  ? 199 PHE D CD1 1 
ATOM   15616 C CD2 . PHE D 1 199 ? 173.690 148.642 109.244 1.00 71.60  ? 199 PHE D CD2 1 
ATOM   15617 C CE1 . PHE D 1 199 ? 171.526 148.794 107.465 1.00 68.32  ? 199 PHE D CE1 1 
ATOM   15618 C CE2 . PHE D 1 199 ? 173.625 149.674 108.307 1.00 67.49  ? 199 PHE D CE2 1 
ATOM   15619 C CZ  . PHE D 1 199 ? 172.552 149.745 107.408 1.00 67.67  ? 199 PHE D CZ  1 
ATOM   15620 N N   . GLN D 1 200 ? 172.199 145.822 113.614 1.00 71.41  ? 200 GLN D N   1 
ATOM   15621 C CA  . GLN D 1 200 ? 172.260 144.854 114.700 1.00 66.74  ? 200 GLN D CA  1 
ATOM   15622 C C   . GLN D 1 200 ? 170.849 144.536 115.217 1.00 67.67  ? 200 GLN D C   1 
ATOM   15623 O O   . GLN D 1 200 ? 169.910 145.280 114.955 1.00 77.83  ? 200 GLN D O   1 
ATOM   15624 C CB  . GLN D 1 200 ? 173.183 145.407 115.790 1.00 72.76  ? 200 GLN D CB  1 
ATOM   15625 C CG  . GLN D 1 200 ? 174.622 145.583 115.268 1.00 77.16  ? 200 GLN D CG  1 
ATOM   15626 C CD  . GLN D 1 200 ? 175.547 146.259 116.266 1.00 76.01  ? 200 GLN D CD  1 
ATOM   15627 O OE1 . GLN D 1 200 ? 175.253 146.412 117.441 1.00 70.44  ? 200 GLN D OE1 1 
ATOM   15628 N NE2 . GLN D 1 200 ? 176.700 146.709 115.837 1.00 71.80  ? 200 GLN D NE2 1 
ATOM   15629 N N   . LYS D 1 201 ? 170.672 143.445 115.971 1.00 70.75  ? 201 LYS D N   1 
ATOM   15630 C CA  . LYS D 1 201 ? 169.373 143.078 116.552 1.00 74.95  ? 201 LYS D CA  1 
ATOM   15631 C C   . LYS D 1 201 ? 169.275 143.584 117.998 1.00 84.47  ? 201 LYS D C   1 
ATOM   15632 O O   . LYS D 1 201 ? 170.060 143.177 118.852 1.00 87.24  ? 201 LYS D O   1 
ATOM   15633 C CB  . LYS D 1 201 ? 169.196 141.557 116.437 1.00 79.85  ? 201 LYS D CB  1 
ATOM   15634 C CG  . LYS D 1 201 ? 167.774 141.106 116.787 1.00 81.24  ? 201 LYS D CG  1 
ATOM   15635 C CD  . LYS D 1 201 ? 167.652 139.583 116.763 1.00 83.23  ? 201 LYS D CD  1 
ATOM   15636 C CE  . LYS D 1 201 ? 166.266 139.154 117.253 1.00 82.05  ? 201 LYS D CE  1 
ATOM   15637 N NZ  . LYS D 1 201 ? 166.227 137.727 117.653 1.00 81.40  ? 201 LYS D NZ  1 
ATOM   15638 N N   . HIS D 1 202 ? 168.321 144.474 118.267 1.00 84.58  ? 202 HIS D N   1 
ATOM   15639 C CA  . HIS D 1 202 ? 168.063 145.101 119.570 1.00 77.58  ? 202 HIS D CA  1 
ATOM   15640 C C   . HIS D 1 202 ? 166.622 145.617 119.678 1.00 79.35  ? 202 HIS D C   1 
ATOM   15641 O O   . HIS D 1 202 ? 165.856 145.562 118.720 1.00 80.60  ? 202 HIS D O   1 
ATOM   15642 C CB  . HIS D 1 202 ? 169.099 146.199 119.841 1.00 78.58  ? 202 HIS D CB  1 
ATOM   15643 C CG  . HIS D 1 202 ? 169.096 147.352 118.878 1.00 82.19  ? 202 HIS D CG  1 
ATOM   15644 N ND1 . HIS D 1 202 ? 168.236 148.450 118.915 1.00 84.61  ? 202 HIS D ND1 1 
ATOM   15645 C CD2 . HIS D 1 202 ? 170.001 147.538 117.883 1.00 83.00  ? 202 HIS D CD2 1 
ATOM   15646 C CE1 . HIS D 1 202 ? 168.645 149.268 117.932 1.00 82.23  ? 202 HIS D CE1 1 
ATOM   15647 N NE2 . HIS D 1 202 ? 169.701 148.738 117.299 1.00 78.62  ? 202 HIS D NE2 1 
ATOM   15648 N N   . GLN D 1 203 ? 166.214 146.057 120.870 1.00 94.84  ? 203 GLN D N   1 
ATOM   15649 C CA  . GLN D 1 203 ? 164.844 146.482 121.170 1.00 98.01  ? 203 GLN D CA  1 
ATOM   15650 C C   . GLN D 1 203 ? 164.411 147.837 120.581 1.00 97.49  ? 203 GLN D C   1 
ATOM   15651 O O   . GLN D 1 203 ? 163.230 148.182 120.656 1.00 97.24  ? 203 GLN D O   1 
ATOM   15652 C CB  . GLN D 1 203 ? 164.705 146.515 122.690 1.00 91.59  ? 203 GLN D CB  1 
ATOM   15653 N N   . GLY D 1 204 ? 165.331 148.631 120.030 1.00 84.46  ? 204 GLY D N   1 
ATOM   15654 C CA  . GLY D 1 204 ? 165.067 149.937 119.422 1.00 84.08  ? 204 GLY D CA  1 
ATOM   15655 C C   . GLY D 1 204 ? 164.672 149.875 117.944 1.00 86.42  ? 204 GLY D C   1 
ATOM   15656 O O   . GLY D 1 204 ? 164.257 148.838 117.427 1.00 81.78  ? 204 GLY D O   1 
ATOM   15657 N N   . THR D 1 205 ? 164.876 150.991 117.247 1.00 87.90  ? 205 THR D N   1 
ATOM   15658 C CA  . THR D 1 205 ? 164.754 151.072 115.786 1.00 83.43  ? 205 THR D CA  1 
ATOM   15659 C C   . THR D 1 205 ? 165.944 150.387 115.124 1.00 87.97  ? 205 THR D C   1 
ATOM   15660 O O   . THR D 1 205 ? 167.068 150.878 115.193 1.00 85.36  ? 205 THR D O   1 
ATOM   15661 C CB  . THR D 1 205 ? 164.639 152.528 115.324 1.00 82.29  ? 205 THR D CB  1 
ATOM   15662 O OG1 . THR D 1 205 ? 163.486 153.099 115.884 1.00 82.33  ? 205 THR D OG1 1 
ATOM   15663 C CG2 . THR D 1 205 ? 164.493 152.662 113.818 1.00 81.23  ? 205 THR D CG2 1 
ATOM   15664 N N   . CYS D 1 206 ? 165.700 149.254 114.476 1.00 82.96  ? 206 CYS D N   1 
ATOM   15665 C CA  . CYS D 1 206 ? 166.705 148.471 113.768 1.00 74.51  ? 206 CYS D CA  1 
ATOM   15666 C C   . CYS D 1 206 ? 166.075 147.623 112.668 1.00 74.86  ? 206 CYS D C   1 
ATOM   15667 O O   . CYS D 1 206 ? 164.864 147.414 112.618 1.00 77.02  ? 206 CYS D O   1 
ATOM   15668 C CB  . CYS D 1 206 ? 167.474 147.576 114.749 1.00 71.17  ? 206 CYS D CB  1 
ATOM   15669 S SG  . CYS D 1 206 ? 166.459 146.214 115.370 1.00 62.37  ? 206 CYS D SG  1 
ATOM   15670 N N   . PHE D 1 207 ? 166.927 147.091 111.789 1.00 60.97  ? 207 PHE D N   1 
ATOM   15671 C CA  . PHE D 1 207 ? 166.598 146.137 110.729 1.00 47.18  ? 207 PHE D CA  1 
ATOM   15672 C C   . PHE D 1 207 ? 167.735 145.130 110.570 1.00 59.77  ? 207 PHE D C   1 
ATOM   15673 O O   . PHE D 1 207 ? 168.664 145.346 109.799 1.00 71.41  ? 207 PHE D O   1 
ATOM   15674 C CB  . PHE D 1 207 ? 166.320 146.894 109.425 1.00 55.46  ? 207 PHE D CB  1 
ATOM   15675 C CG  . PHE D 1 207 ? 166.116 146.052 108.173 1.00 60.39  ? 207 PHE D CG  1 
ATOM   15676 C CD1 . PHE D 1 207 ? 165.256 144.940 108.167 1.00 62.12  ? 207 PHE D CD1 1 
ATOM   15677 C CD2 . PHE D 1 207 ? 166.760 146.422 106.986 1.00 63.13  ? 207 PHE D CD2 1 
ATOM   15678 C CE1 . PHE D 1 207 ? 165.030 144.226 106.980 1.00 58.47  ? 207 PHE D CE1 1 
ATOM   15679 C CE2 . PHE D 1 207 ? 166.527 145.716 105.794 1.00 59.27  ? 207 PHE D CE2 1 
ATOM   15680 C CZ  . PHE D 1 207 ? 165.662 144.618 105.792 1.00 58.81  ? 207 PHE D CZ  1 
ATOM   15681 N N   . TYR D 1 208 ? 167.688 144.030 111.318 1.00 68.57  ? 208 TYR D N   1 
ATOM   15682 C CA  . TYR D 1 208 ? 168.610 142.911 111.143 1.00 66.68  ? 208 TYR D CA  1 
ATOM   15683 C C   . TYR D 1 208 ? 168.212 142.072 109.922 1.00 76.81  ? 208 TYR D C   1 
ATOM   15684 O O   . TYR D 1 208 ? 167.077 141.617 109.819 1.00 80.21  ? 208 TYR D O   1 
ATOM   15685 C CB  . TYR D 1 208 ? 168.654 142.066 112.422 1.00 63.93  ? 208 TYR D CB  1 
ATOM   15686 C CG  . TYR D 1 208 ? 169.636 140.914 112.362 1.00 67.40  ? 208 TYR D CG  1 
ATOM   15687 C CD1 . TYR D 1 208 ? 171.003 141.144 112.596 1.00 70.41  ? 208 TYR D CD1 1 
ATOM   15688 C CD2 . TYR D 1 208 ? 169.197 139.620 112.028 1.00 71.99  ? 208 TYR D CD2 1 
ATOM   15689 C CE1 . TYR D 1 208 ? 171.937 140.104 112.463 1.00 61.66  ? 208 TYR D CE1 1 
ATOM   15690 C CE2 . TYR D 1 208 ? 170.127 138.576 111.893 1.00 72.05  ? 208 TYR D CE2 1 
ATOM   15691 C CZ  . TYR D 1 208 ? 171.498 138.820 112.096 1.00 67.56  ? 208 TYR D CZ  1 
ATOM   15692 O OH  . TYR D 1 208 ? 172.392 137.823 111.904 1.00 76.90  ? 208 TYR D OH  1 
ATOM   15693 N N   . PHE D 1 209 ? 169.156 141.828 109.015 1.00 67.38  ? 209 PHE D N   1 
ATOM   15694 C CA  . PHE D 1 209 ? 169.011 140.978 107.830 1.00 60.55  ? 209 PHE D CA  1 
ATOM   15695 C C   . PHE D 1 209 ? 170.200 140.023 107.690 1.00 65.32  ? 209 PHE D C   1 
ATOM   15696 O O   . PHE D 1 209 ? 170.509 139.555 106.598 1.00 80.10  ? 209 PHE D O   1 
ATOM   15697 C CB  . PHE D 1 209 ? 168.788 141.848 106.587 1.00 64.60  ? 209 PHE D CB  1 
ATOM   15698 C CG  . PHE D 1 209 ? 169.847 142.897 106.316 1.00 61.99  ? 209 PHE D CG  1 
ATOM   15699 C CD1 . PHE D 1 209 ? 171.075 142.567 105.719 1.00 65.75  ? 209 PHE D CD1 1 
ATOM   15700 C CD2 . PHE D 1 209 ? 169.583 144.234 106.637 1.00 60.83  ? 209 PHE D CD2 1 
ATOM   15701 C CE1 . PHE D 1 209 ? 172.025 143.562 105.443 1.00 64.16  ? 209 PHE D CE1 1 
ATOM   15702 C CE2 . PHE D 1 209 ? 170.511 145.231 106.326 1.00 68.56  ? 209 PHE D CE2 1 
ATOM   15703 C CZ  . PHE D 1 209 ? 171.735 144.898 105.734 1.00 66.38  ? 209 PHE D CZ  1 
ATOM   15704 N N   . GLY D 1 210 ? 170.913 139.739 108.774 1.00 65.64  ? 210 GLY D N   1 
ATOM   15705 C CA  . GLY D 1 210 ? 172.329 139.399 108.681 1.00 63.66  ? 210 GLY D CA  1 
ATOM   15706 C C   . GLY D 1 210 ? 173.099 140.709 108.504 1.00 75.75  ? 210 GLY D C   1 
ATOM   15707 O O   . GLY D 1 210 ? 172.636 141.755 108.952 1.00 85.30  ? 210 GLY D O   1 
ATOM   15708 N N   . GLU D 1 211 ? 174.231 140.702 107.807 1.00 73.21  ? 211 GLU D N   1 
ATOM   15709 C CA  . GLU D 1 211 ? 174.938 141.948 107.445 1.00 73.08  ? 211 GLU D CA  1 
ATOM   15710 C C   . GLU D 1 211 ? 175.353 142.020 105.974 1.00 76.25  ? 211 GLU D C   1 
ATOM   15711 O O   . GLU D 1 211 ? 175.818 143.053 105.504 1.00 89.32  ? 211 GLU D O   1 
ATOM   15712 C CB  . GLU D 1 211 ? 176.167 142.134 108.338 1.00 76.05  ? 211 GLU D CB  1 
ATOM   15713 C CG  . GLU D 1 211 ? 175.809 142.325 109.817 1.00 75.41  ? 211 GLU D CG  1 
ATOM   15714 C CD  . GLU D 1 211 ? 177.036 142.391 110.732 1.00 85.16  ? 211 GLU D CD  1 
ATOM   15715 O OE1 . GLU D 1 211 ? 178.192 142.165 110.289 1.00 82.67  ? 211 GLU D OE1 1 
ATOM   15716 O OE2 . GLU D 1 211 ? 176.829 142.594 111.945 1.00 85.92  ? 211 GLU D OE2 1 
ATOM   15717 N N   . LEU D 1 212 ? 175.215 140.929 105.232 1.00 70.83  ? 212 LEU D N   1 
ATOM   15718 C CA  . LEU D 1 212 ? 175.766 140.772 103.889 1.00 74.21  ? 212 LEU D CA  1 
ATOM   15719 C C   . LEU D 1 212 ? 174.700 141.011 102.815 1.00 71.56  ? 212 LEU D C   1 
ATOM   15720 O O   . LEU D 1 212 ? 173.531 140.700 103.046 1.00 71.84  ? 212 LEU D O   1 
ATOM   15721 C CB  . LEU D 1 212 ? 176.355 139.361 103.758 1.00 79.35  ? 212 LEU D CB  1 
ATOM   15722 C CG  . LEU D 1 212 ? 177.530 139.063 104.700 1.00 74.74  ? 212 LEU D CG  1 
ATOM   15723 C CD1 . LEU D 1 212 ? 177.695 137.564 104.842 1.00 74.50  ? 212 LEU D CD1 1 
ATOM   15724 C CD2 . LEU D 1 212 ? 178.827 139.632 104.157 1.00 72.20  ? 212 LEU D CD2 1 
ATOM   15725 N N   . PRO D 1 213 ? 175.090 141.459 101.612 1.00 76.65  ? 213 PRO D N   1 
ATOM   15726 C CA  . PRO D 1 213 ? 174.236 141.509 100.430 1.00 82.91  ? 213 PRO D CA  1 
ATOM   15727 C C   . PRO D 1 213 ? 173.424 140.236 100.172 1.00 82.76  ? 213 PRO D C   1 
ATOM   15728 O O   . PRO D 1 213 ? 172.223 140.320 99.943  1.00 83.45  ? 213 PRO D O   1 
ATOM   15729 C CB  . PRO D 1 213 ? 175.204 141.802 99.283  1.00 82.79  ? 213 PRO D CB  1 
ATOM   15730 C CG  . PRO D 1 213 ? 176.236 142.701 99.938  1.00 78.44  ? 213 PRO D CG  1 
ATOM   15731 C CD  . PRO D 1 213 ? 176.370 142.071 101.315 1.00 77.28  ? 213 PRO D CD  1 
ATOM   15732 N N   . LEU D 1 214 ? 174.015 139.040 100.264 1.00 78.27  ? 214 LEU D N   1 
ATOM   15733 C CA  . LEU D 1 214 ? 173.275 137.790 100.055 1.00 79.43  ? 214 LEU D CA  1 
ATOM   15734 C C   . LEU D 1 214 ? 172.192 137.554 101.118 1.00 80.30  ? 214 LEU D C   1 
ATOM   15735 O O   . LEU D 1 214 ? 171.086 137.125 100.796 1.00 84.17  ? 214 LEU D O   1 
ATOM   15736 C CB  . LEU D 1 214 ? 174.264 136.617 99.994  1.00 77.12  ? 214 LEU D CB  1 
ATOM   15737 C CG  . LEU D 1 214 ? 173.586 135.246 99.810  1.00 79.96  ? 214 LEU D CG  1 
ATOM   15738 C CD1 . LEU D 1 214 ? 172.842 135.139 98.487  1.00 78.42  ? 214 LEU D CD1 1 
ATOM   15739 C CD2 . LEU D 1 214 ? 174.621 134.136 99.879  1.00 85.25  ? 214 LEU D CD2 1 
ATOM   15740 N N   . SER D 1 215 ? 172.482 137.860 102.380 1.00 63.13  ? 215 SER D N   1 
ATOM   15741 C CA  . SER D 1 215 ? 171.507 137.725 103.460 1.00 56.65  ? 215 SER D CA  1 
ATOM   15742 C C   . SER D 1 215 ? 170.389 138.760 103.354 1.00 65.11  ? 215 SER D C   1 
ATOM   15743 O O   . SER D 1 215 ? 169.230 138.428 103.576 1.00 69.89  ? 215 SER D O   1 
ATOM   15744 C CB  . SER D 1 215 ? 172.186 137.814 104.819 1.00 61.77  ? 215 SER D CB  1 
ATOM   15745 O OG  . SER D 1 215 ? 173.331 136.984 104.854 1.00 66.05  ? 215 SER D OG  1 
ATOM   15746 N N   . LEU D 1 216 ? 170.682 139.986 102.914 1.00 72.30  ? 216 LEU D N   1 
ATOM   15747 C CA  . LEU D 1 216 ? 169.668 140.988 102.591 1.00 70.80  ? 216 LEU D CA  1 
ATOM   15748 C C   . LEU D 1 216 ? 168.750 140.522 101.460 1.00 70.71  ? 216 LEU D C   1 
ATOM   15749 O O   . LEU D 1 216 ? 167.531 140.597 101.584 1.00 76.10  ? 216 LEU D O   1 
ATOM   15750 C CB  . LEU D 1 216 ? 170.368 142.310 102.242 1.00 68.23  ? 216 LEU D CB  1 
ATOM   15751 C CG  . LEU D 1 216 ? 169.429 143.476 101.901 1.00 62.23  ? 216 LEU D CG  1 
ATOM   15752 C CD1 . LEU D 1 216 ? 168.408 143.815 102.977 1.00 65.90  ? 216 LEU D CD1 1 
ATOM   15753 C CD2 . LEU D 1 216 ? 170.273 144.714 101.666 1.00 65.56  ? 216 LEU D CD2 1 
ATOM   15754 N N   . ALA D 1 217 ? 169.304 140.006 100.364 1.00 65.83  ? 217 ALA D N   1 
ATOM   15755 C CA  . ALA D 1 217 ? 168.529 139.509 99.234  1.00 56.94  ? 217 ALA D CA  1 
ATOM   15756 C C   . ALA D 1 217 ? 167.610 138.338 99.622  1.00 65.96  ? 217 ALA D C   1 
ATOM   15757 O O   . ALA D 1 217 ? 166.454 138.295 99.214  1.00 67.55  ? 217 ALA D O   1 
ATOM   15758 C CB  . ALA D 1 217 ? 169.506 139.131 98.122  1.00 59.69  ? 217 ALA D CB  1 
ATOM   15759 N N   . ALA D 1 218 ? 168.079 137.422 100.470 1.00 76.50  ? 218 ALA D N   1 
ATOM   15760 C CA  . ALA D 1 218 ? 167.262 136.347 101.023 1.00 66.26  ? 218 ALA D CA  1 
ATOM   15761 C C   . ALA D 1 218 ? 166.142 136.872 101.938 1.00 65.51  ? 218 ALA D C   1 
ATOM   15762 O O   . ALA D 1 218 ? 164.982 136.512 101.772 1.00 68.17  ? 218 ALA D O   1 
ATOM   15763 C CB  . ALA D 1 218 ? 168.190 135.379 101.758 1.00 58.56  ? 218 ALA D CB  1 
ATOM   15764 N N   . CYS D 1 219 ? 166.434 137.768 102.877 1.00 79.47  ? 219 CYS D N   1 
ATOM   15765 C CA  . CYS D 1 219 ? 165.437 138.254 103.834 1.00 81.32  ? 219 CYS D CA  1 
ATOM   15766 C C   . CYS D 1 219 ? 164.372 139.174 103.206 1.00 78.10  ? 219 CYS D C   1 
ATOM   15767 O O   . CYS D 1 219 ? 163.218 139.165 103.621 1.00 71.56  ? 219 CYS D O   1 
ATOM   15768 C CB  . CYS D 1 219 ? 166.174 138.917 104.996 1.00 79.96  ? 219 CYS D CB  1 
ATOM   15769 S SG  . CYS D 1 219 ? 167.246 137.678 105.771 1.00 86.37  ? 219 CYS D SG  1 
ATOM   15770 N N   . THR D 1 220 ? 164.728 139.908 102.151 1.00 82.77  ? 220 THR D N   1 
ATOM   15771 C CA  . THR D 1 220 ? 163.804 140.664 101.285 1.00 79.27  ? 220 THR D CA  1 
ATOM   15772 C C   . THR D 1 220 ? 163.126 139.799 100.205 1.00 81.98  ? 220 THR D C   1 
ATOM   15773 O O   . THR D 1 220 ? 162.344 140.321 99.412  1.00 87.06  ? 220 THR D O   1 
ATOM   15774 C CB  . THR D 1 220 ? 164.514 141.850 100.629 1.00 78.29  ? 220 THR D CB  1 
ATOM   15775 O OG1 . THR D 1 220 ? 165.618 141.409 99.893  1.00 86.61  ? 220 THR D OG1 1 
ATOM   15776 C CG2 . THR D 1 220 ? 165.050 142.877 101.610 1.00 75.83  ? 220 THR D CG2 1 
ATOM   15777 N N   . LYS D 1 221 ? 163.356 138.480 100.185 1.00 81.99  ? 221 LYS D N   1 
ATOM   15778 C CA  . LYS D 1 221 ? 162.661 137.478 99.353  1.00 77.90  ? 221 LYS D CA  1 
ATOM   15779 C C   . LYS D 1 221 ? 162.889 137.610 97.848  1.00 82.40  ? 221 LYS D C   1 
ATOM   15780 O O   . LYS D 1 221 ? 161.959 137.474 97.059  1.00 82.24  ? 221 LYS D O   1 
ATOM   15781 C CB  . LYS D 1 221 ? 161.169 137.380 99.720  1.00 75.26  ? 221 LYS D CB  1 
ATOM   15782 C CG  . LYS D 1 221 ? 160.909 137.379 101.230 1.00 85.62  ? 221 LYS D CG  1 
ATOM   15783 C CD  . LYS D 1 221 ? 159.447 137.045 101.534 1.00 88.13  ? 221 LYS D CD  1 
ATOM   15784 C CE  . LYS D 1 221 ? 159.025 137.435 102.954 1.00 85.75  ? 221 LYS D CE  1 
ATOM   15785 N NZ  . LYS D 1 221 ? 159.932 136.926 104.014 1.00 78.73  ? 221 LYS D NZ  1 
ATOM   15786 N N   . GLN D 1 222 ? 164.115 137.906 97.429  1.00 89.99  ? 222 GLN D N   1 
ATOM   15787 C CA  . GLN D 1 222 ? 164.460 138.180 96.032  1.00 88.80  ? 222 GLN D CA  1 
ATOM   15788 C C   . GLN D 1 222 ? 165.208 137.015 95.378  1.00 83.80  ? 222 GLN D C   1 
ATOM   15789 O O   . GLN D 1 222 ? 166.432 137.019 95.317  1.00 82.58  ? 222 GLN D O   1 
ATOM   15790 C CB  . GLN D 1 222 ? 165.272 139.475 95.959  1.00 87.15  ? 222 GLN D CB  1 
ATOM   15791 C CG  . GLN D 1 222 ? 164.465 140.668 96.459  1.00 83.35  ? 222 GLN D CG  1 
ATOM   15792 C CD  . GLN D 1 222 ? 165.226 141.955 96.250  1.00 84.88  ? 222 GLN D CD  1 
ATOM   15793 O OE1 . GLN D 1 222 ? 165.367 142.442 95.145  1.00 93.37  ? 222 GLN D OE1 1 
ATOM   15794 N NE2 . GLN D 1 222 ? 165.736 142.549 97.298  1.00 84.40  ? 222 GLN D NE2 1 
ATOM   15795 N N   . TRP D 1 223 ? 164.498 136.018 94.886  1.00 88.66  ? 223 TRP D N   1 
ATOM   15796 C CA  . TRP D 1 223 ? 165.273 134.887 94.336  1.00 96.10  ? 223 TRP D CA  1 
ATOM   15797 C C   . TRP D 1 223 ? 166.197 135.384 93.221  1.00 100.91 ? 223 TRP D C   1 
ATOM   15798 O O   . TRP D 1 223 ? 167.383 135.077 93.294  1.00 104.35 ? 223 TRP D O   1 
ATOM   15799 C CB  . TRP D 1 223 ? 164.336 133.772 93.876  1.00 95.88  ? 223 TRP D CB  1 
ATOM   15800 C CG  . TRP D 1 223 ? 163.852 132.904 94.992  1.00 101.37 ? 223 TRP D CG  1 
ATOM   15801 C CD1 . TRP D 1 223 ? 162.595 132.861 95.520  1.00 99.58  ? 223 TRP D CD1 1 
ATOM   15802 C CD2 . TRP D 1 223 ? 164.629 131.946 95.728  1.00 101.45 ? 223 TRP D CD2 1 
ATOM   15803 N NE1 . TRP D 1 223 ? 162.534 131.940 96.531  1.00 95.37  ? 223 TRP D NE1 1 
ATOM   15804 C CE2 . TRP D 1 223 ? 163.768 131.364 96.681  1.00 100.80 ? 223 TRP D CE2 1 
ATOM   15805 C CE3 . TRP D 1 223 ? 165.960 131.525 95.672  1.00 92.48  ? 223 TRP D CE3 1 
ATOM   15806 C CZ2 . TRP D 1 223 ? 164.199 130.382 97.567  1.00 100.23 ? 223 TRP D CZ2 1 
ATOM   15807 C CZ3 . TRP D 1 223 ? 166.383 130.560 96.554  1.00 89.91  ? 223 TRP D CZ3 1 
ATOM   15808 C CH2 . TRP D 1 223 ? 165.516 130.000 97.487  1.00 97.43  ? 223 TRP D CH2 1 
ATOM   15809 N N   . ASP D 1 224 ? 165.697 136.134 92.240  1.00 102.49 ? 224 ASP D N   1 
ATOM   15810 C CA  . ASP D 1 224 ? 166.509 136.539 91.094  1.00 98.87  ? 224 ASP D CA  1 
ATOM   15811 C C   . ASP D 1 224 ? 167.806 137.241 91.522  1.00 100.19 ? 224 ASP D C   1 
ATOM   15812 O O   . ASP D 1 224 ? 168.872 136.928 90.996  1.00 98.08  ? 224 ASP D O   1 
ATOM   15813 C CB  . ASP D 1 224 ? 165.677 137.395 90.125  1.00 101.23 ? 224 ASP D CB  1 
ATOM   15814 C CG  . ASP D 1 224 ? 164.931 138.599 90.724  1.00 102.97 ? 224 ASP D CG  1 
ATOM   15815 O OD1 . ASP D 1 224 ? 164.949 138.790 91.958  1.00 101.21 ? 224 ASP D OD1 1 
ATOM   15816 O OD2 . ASP D 1 224 ? 164.293 139.333 89.943  1.00 105.91 ? 224 ASP D OD2 1 
ATOM   15817 N N   . VAL D 1 225 ? 167.748 138.123 92.519  1.00 97.07  ? 225 VAL D N   1 
ATOM   15818 C CA  . VAL D 1 225 ? 168.940 138.740 93.119  1.00 94.41  ? 225 VAL D CA  1 
ATOM   15819 C C   . VAL D 1 225 ? 169.774 137.710 93.875  1.00 93.37  ? 225 VAL D C   1 
ATOM   15820 O O   . VAL D 1 225 ? 170.988 137.699 93.717  1.00 98.40  ? 225 VAL D O   1 
ATOM   15821 C CB  . VAL D 1 225 ? 168.578 139.927 94.027  1.00 95.55  ? 225 VAL D CB  1 
ATOM   15822 C CG1 . VAL D 1 225 ? 169.820 140.567 94.644  1.00 94.92  ? 225 VAL D CG1 1 
ATOM   15823 C CG2 . VAL D 1 225 ? 167.854 141.025 93.247  1.00 91.91  ? 225 VAL D CG2 1 
ATOM   15824 N N   . VAL D 1 226 ? 169.166 136.806 94.648  1.00 89.11  ? 226 VAL D N   1 
ATOM   15825 C CA  . VAL D 1 226 ? 169.876 135.716 95.347  1.00 91.23  ? 226 VAL D CA  1 
ATOM   15826 C C   . VAL D 1 226 ? 170.602 134.820 94.351  1.00 93.98  ? 226 VAL D C   1 
ATOM   15827 O O   . VAL D 1 226 ? 171.786 134.562 94.520  1.00 93.45  ? 226 VAL D O   1 
ATOM   15828 C CB  . VAL D 1 226 ? 168.905 134.891 96.211  1.00 90.72  ? 226 VAL D CB  1 
ATOM   15829 C CG1 . VAL D 1 226 ? 169.464 133.541 96.655  1.00 91.00  ? 226 VAL D CG1 1 
ATOM   15830 C CG2 . VAL D 1 226 ? 168.541 135.663 97.477  1.00 94.22  ? 226 VAL D CG2 1 
ATOM   15831 N N   . THR D 1 227 ? 169.927 134.405 93.278  1.00 102.83 ? 227 THR D N   1 
ATOM   15832 C CA  . THR D 1 227 ? 170.542 133.633 92.197  1.00 98.87  ? 227 THR D CA  1 
ATOM   15833 C C   . THR D 1 227 ? 171.692 134.414 91.567  1.00 96.43  ? 227 THR D C   1 
ATOM   15834 O O   . THR D 1 227 ? 172.787 133.884 91.421  1.00 95.56  ? 227 THR D O   1 
ATOM   15835 C CB  . THR D 1 227 ? 169.511 133.276 91.117  1.00 95.88  ? 227 THR D CB  1 
ATOM   15836 O OG1 . THR D 1 227 ? 168.437 132.562 91.677  1.00 95.91  ? 227 THR D OG1 1 
ATOM   15837 C CG2 . THR D 1 227 ? 170.102 132.413 90.011  1.00 93.62  ? 227 THR D CG2 1 
ATOM   15838 N N   . TYR D 1 228 ? 171.498 135.693 91.237  1.00 97.65  ? 228 TYR D N   1 
ATOM   15839 C CA  . TYR D 1 228 ? 172.565 136.487 90.643  1.00 98.45  ? 228 TYR D CA  1 
ATOM   15840 C C   . TYR D 1 228 ? 173.771 136.623 91.583  1.00 100.56 ? 228 TYR D C   1 
ATOM   15841 O O   . TYR D 1 228 ? 174.898 136.316 91.201  1.00 103.20 ? 228 TYR D O   1 
ATOM   15842 C CB  . TYR D 1 228 ? 172.023 137.846 90.204  1.00 98.98  ? 228 TYR D CB  1 
ATOM   15843 C CG  . TYR D 1 228 ? 173.088 138.639 89.489  1.00 99.66  ? 228 TYR D CG  1 
ATOM   15844 C CD1 . TYR D 1 228 ? 173.419 138.304 88.164  1.00 99.87  ? 228 TYR D CD1 1 
ATOM   15845 C CD2 . TYR D 1 228 ? 173.852 139.587 90.188  1.00 96.13  ? 228 TYR D CD2 1 
ATOM   15846 C CE1 . TYR D 1 228 ? 174.529 138.896 87.543  1.00 98.83  ? 228 TYR D CE1 1 
ATOM   15847 C CE2 . TYR D 1 228 ? 174.965 140.180 89.571  1.00 100.68 ? 228 TYR D CE2 1 
ATOM   15848 C CZ  . TYR D 1 228 ? 175.309 139.832 88.252  1.00 102.77 ? 228 TYR D CZ  1 
ATOM   15849 O OH  . TYR D 1 228 ? 176.390 140.395 87.660  1.00 102.45 ? 228 TYR D OH  1 
ATOM   15850 N N   . LEU D 1 229 ? 173.565 137.012 92.840  1.00 95.55  ? 229 LEU D N   1 
ATOM   15851 C CA  . LEU D 1 229 ? 174.657 137.129 93.802  1.00 95.14  ? 229 LEU D CA  1 
ATOM   15852 C C   . LEU D 1 229 ? 175.390 135.797 93.976  1.00 97.35  ? 229 LEU D C   1 
ATOM   15853 O O   . LEU D 1 229 ? 176.615 135.799 93.994  1.00 94.28  ? 229 LEU D O   1 
ATOM   15854 C CB  . LEU D 1 229 ? 174.121 137.652 95.143  1.00 94.99  ? 229 LEU D CB  1 
ATOM   15855 C CG  . LEU D 1 229 ? 173.681 139.123 95.134  1.00 90.89  ? 229 LEU D CG  1 
ATOM   15856 C CD1 . LEU D 1 229 ? 173.066 139.453 96.484  1.00 90.30  ? 229 LEU D CD1 1 
ATOM   15857 C CD2 . LEU D 1 229 ? 174.834 140.090 94.903  1.00 90.27  ? 229 LEU D CD2 1 
ATOM   15858 N N   . LEU D 1 230 ? 174.685 134.664 94.046  1.00 100.46 ? 230 LEU D N   1 
ATOM   15859 C CA  . LEU D 1 230 ? 175.291 133.340 94.217  1.00 95.50  ? 230 LEU D CA  1 
ATOM   15860 C C   . LEU D 1 230 ? 176.090 132.835 93.016  1.00 96.09  ? 230 LEU D C   1 
ATOM   15861 O O   . LEU D 1 230 ? 177.104 132.174 93.221  1.00 91.65  ? 230 LEU D O   1 
ATOM   15862 C CB  . LEU D 1 230 ? 174.196 132.312 94.526  1.00 91.60  ? 230 LEU D CB  1 
ATOM   15863 C CG  . LEU D 1 230 ? 173.695 132.344 95.970  1.00 90.37  ? 230 LEU D CG  1 
ATOM   15864 C CD1 . LEU D 1 230 ? 172.542 131.362 96.142  1.00 93.64  ? 230 LEU D CD1 1 
ATOM   15865 C CD2 . LEU D 1 230 ? 174.777 131.934 96.952  1.00 89.07  ? 230 LEU D CD2 1 
ATOM   15866 N N   . GLU D 1 231 ? 175.652 133.091 91.779  1.00 109.66 ? 231 GLU D N   1 
ATOM   15867 C CA  . GLU D 1 231 ? 176.237 132.448 90.591  1.00 107.89 ? 231 GLU D CA  1 
ATOM   15868 C C   . GLU D 1 231 ? 176.575 133.385 89.409  1.00 108.07 ? 231 GLU D C   1 
ATOM   15869 O O   . GLU D 1 231 ? 176.783 132.921 88.291  1.00 112.19 ? 231 GLU D O   1 
ATOM   15870 C CB  . GLU D 1 231 ? 175.458 131.164 90.228  1.00 108.80 ? 231 GLU D CB  1 
ATOM   15871 C CG  . GLU D 1 231 ? 173.957 131.344 89.974  1.00 108.57 ? 231 GLU D CG  1 
ATOM   15872 C CD  . GLU D 1 231 ? 173.302 130.063 89.436  1.00 110.65 ? 231 GLU D CD  1 
ATOM   15873 O OE1 . GLU D 1 231 ? 173.309 129.019 90.130  1.00 110.74 ? 231 GLU D OE1 1 
ATOM   15874 O OE2 . GLU D 1 231 ? 172.753 130.099 88.311  1.00 108.37 ? 231 GLU D OE2 1 
ATOM   15875 N N   . ASN D 1 232 ? 176.718 134.695 89.636  1.00 108.03 ? 232 ASN D N   1 
ATOM   15876 C CA  . ASN D 1 232 ? 177.395 135.592 88.690  1.00 110.37 ? 232 ASN D CA  1 
ATOM   15877 C C   . ASN D 1 232 ? 178.898 135.246 88.536  1.00 113.30 ? 232 ASN D C   1 
ATOM   15878 O O   . ASN D 1 232 ? 179.510 134.734 89.478  1.00 113.21 ? 232 ASN D O   1 
ATOM   15879 C CB  . ASN D 1 232 ? 177.211 137.063 89.110  1.00 111.34 ? 232 ASN D CB  1 
ATOM   15880 C CG  . ASN D 1 232 ? 178.101 137.470 90.271  1.00 108.53 ? 232 ASN D CG  1 
ATOM   15881 O OD1 . ASN D 1 232 ? 179.227 137.893 90.074  1.00 107.48 ? 232 ASN D OD1 1 
ATOM   15882 N ND2 . ASN D 1 232 ? 177.645 137.346 91.488  1.00 107.06 ? 232 ASN D ND2 1 
ATOM   15883 N N   . PRO D 1 233 ? 179.532 135.543 87.385  1.00 117.97 ? 233 PRO D N   1 
ATOM   15884 C CA  . PRO D 1 233 ? 180.941 135.222 87.146  1.00 117.40 ? 233 PRO D CA  1 
ATOM   15885 C C   . PRO D 1 233 ? 181.942 136.235 87.733  1.00 117.22 ? 233 PRO D C   1 
ATOM   15886 O O   . PRO D 1 233 ? 183.142 135.963 87.734  1.00 115.05 ? 233 PRO D O   1 
ATOM   15887 C CB  . PRO D 1 233 ? 181.055 135.163 85.622  1.00 114.29 ? 233 PRO D CB  1 
ATOM   15888 C CG  . PRO D 1 233 ? 180.045 136.206 85.159  1.00 114.59 ? 233 PRO D CG  1 
ATOM   15889 C CD  . PRO D 1 233 ? 178.911 136.040 86.167  1.00 114.98 ? 233 PRO D CD  1 
ATOM   15890 N N   . HIS D 1 234 ? 181.494 137.408 88.189  1.00 118.20 ? 234 HIS D N   1 
ATOM   15891 C CA  . HIS D 1 234 ? 182.371 138.511 88.616  1.00 118.76 ? 234 HIS D CA  1 
ATOM   15892 C C   . HIS D 1 234 ? 182.873 138.333 90.050  1.00 121.25 ? 234 HIS D C   1 
ATOM   15893 O O   . HIS D 1 234 ? 184.075 138.355 90.300  1.00 120.06 ? 234 HIS D O   1 
ATOM   15894 C CB  . HIS D 1 234 ? 181.638 139.851 88.450  1.00 117.31 ? 234 HIS D CB  1 
ATOM   15895 C CG  . HIS D 1 234 ? 181.058 140.043 87.074  1.00 116.42 ? 234 HIS D CG  1 
ATOM   15896 N ND1 . HIS D 1 234 ? 181.795 140.235 85.905  1.00 117.99 ? 234 HIS D ND1 1 
ATOM   15897 C CD2 . HIS D 1 234 ? 179.733 139.995 86.760  1.00 116.94 ? 234 HIS D CD2 1 
ATOM   15898 C CE1 . HIS D 1 234 ? 180.893 140.297 84.914  1.00 120.01 ? 234 HIS D CE1 1 
ATOM   15899 N NE2 . HIS D 1 234 ? 179.650 140.151 85.396  1.00 119.63 ? 234 HIS D NE2 1 
ATOM   15900 N N   . GLN D 1 235 ? 181.916 138.036 90.938  1.00 119.94 ? 235 GLN D N   1 
ATOM   15901 C CA  . GLN D 1 235 ? 182.225 137.766 92.362  1.00 116.37 ? 235 GLN D CA  1 
ATOM   15902 C C   . GLN D 1 235 ? 181.028 136.995 92.929  1.00 119.53 ? 235 GLN D C   1 
ATOM   15903 O O   . GLN D 1 235 ? 180.030 137.652 93.264  1.00 117.29 ? 235 GLN D O   1 
ATOM   15904 C CB  . GLN D 1 235 ? 182.443 139.070 93.124  1.00 115.66 ? 235 GLN D CB  1 
ATOM   15905 C CG  . GLN D 1 235 ? 182.467 138.887 94.634  1.00 120.55 ? 235 GLN D CG  1 
ATOM   15906 C CD  . GLN D 1 235 ? 183.034 140.083 95.357  1.00 120.68 ? 235 GLN D CD  1 
ATOM   15907 O OE1 . GLN D 1 235 ? 183.288 141.128 94.764  1.00 116.82 ? 235 GLN D OE1 1 
ATOM   15908 N NE2 . GLN D 1 235 ? 183.238 139.933 96.655  1.00 118.62 ? 235 GLN D NE2 1 
ATOM   15909 N N   . PRO D 1 236 ? 181.044 135.641 92.984  1.00 117.84 ? 236 PRO D N   1 
ATOM   15910 C CA  . PRO D 1 236 ? 179.964 134.863 93.571  1.00 115.34 ? 236 PRO D CA  1 
ATOM   15911 C C   . PRO D 1 236 ? 179.949 135.032 95.096  1.00 111.69 ? 236 PRO D C   1 
ATOM   15912 O O   . PRO D 1 236 ? 180.988 134.971 95.754  1.00 109.82 ? 236 PRO D O   1 
ATOM   15913 C CB  . PRO D 1 236 ? 180.226 133.424 93.130  1.00 110.66 ? 236 PRO D CB  1 
ATOM   15914 C CG  . PRO D 1 236 ? 181.735 133.367 92.932  1.00 109.75 ? 236 PRO D CG  1 
ATOM   15915 C CD  . PRO D 1 236 ? 182.092 134.775 92.473  1.00 111.32 ? 236 PRO D CD  1 
ATOM   15916 N N   . ALA D 1 237 ? 178.765 135.241 95.662  1.00 104.22 ? 237 ALA D N   1 
ATOM   15917 C CA  . ALA D 1 237 ? 178.540 135.267 97.093  1.00 102.71 ? 237 ALA D CA  1 
ATOM   15918 C C   . ALA D 1 237 ? 178.835 133.890 97.694  1.00 107.33 ? 237 ALA D C   1 
ATOM   15919 O O   . ALA D 1 237 ? 178.272 132.882 97.271  1.00 108.63 ? 237 ALA D O   1 
ATOM   15920 C CB  . ALA D 1 237 ? 177.096 135.688 97.360  1.00 99.93  ? 237 ALA D CB  1 
ATOM   15921 N N   . SER D 1 238 ? 179.707 133.812 98.692  1.00 97.91  ? 238 SER D N   1 
ATOM   15922 C CA  . SER D 1 238 ? 179.944 132.561 99.401  1.00 94.82  ? 238 SER D CA  1 
ATOM   15923 C C   . SER D 1 238 ? 178.783 132.267 100.349 1.00 96.55  ? 238 SER D C   1 
ATOM   15924 O O   . SER D 1 238 ? 178.488 133.064 101.235 1.00 96.76  ? 238 SER D O   1 
ATOM   15925 C CB  . SER D 1 238 ? 181.274 132.631 100.142 1.00 95.03  ? 238 SER D CB  1 
ATOM   15926 O OG  . SER D 1 238 ? 181.519 131.408 100.797 1.00 99.13  ? 238 SER D OG  1 
ATOM   15927 N N   . LEU D 1 239 ? 178.148 131.102 100.215 1.00 93.87  ? 239 LEU D N   1 
ATOM   15928 C CA  . LEU D 1 239 ? 177.173 130.614 101.197 1.00 91.60  ? 239 LEU D CA  1 
ATOM   15929 C C   . LEU D 1 239 ? 177.809 130.345 102.563 1.00 90.88  ? 239 LEU D C   1 
ATOM   15930 O O   . LEU D 1 239 ? 177.094 130.261 103.549 1.00 90.25  ? 239 LEU D O   1 
ATOM   15931 C CB  . LEU D 1 239 ? 176.492 129.342 100.667 1.00 92.24  ? 239 LEU D CB  1 
ATOM   15932 C CG  . LEU D 1 239 ? 175.431 129.653 99.608  1.00 91.60  ? 239 LEU D CG  1 
ATOM   15933 C CD1 . LEU D 1 239 ? 175.147 128.438 98.744  1.00 94.30  ? 239 LEU D CD1 1 
ATOM   15934 C CD2 . LEU D 1 239 ? 174.117 130.081 100.251 1.00 87.45  ? 239 LEU D CD2 1 
ATOM   15935 N N   . GLU D 1 240 ? 179.133 130.228 102.649 1.00 99.05  ? 240 GLU D N   1 
ATOM   15936 C CA  . GLU D 1 240 ? 179.864 130.082 103.908 1.00 101.82 ? 240 GLU D CA  1 
ATOM   15937 C C   . GLU D 1 240 ? 180.133 131.419 104.622 1.00 104.53 ? 240 GLU D C   1 
ATOM   15938 O O   . GLU D 1 240 ? 180.652 131.414 105.737 1.00 105.99 ? 240 GLU D O   1 
ATOM   15939 C CB  . GLU D 1 240 ? 181.210 129.387 103.656 1.00 101.81 ? 240 GLU D CB  1 
ATOM   15940 C CG  . GLU D 1 240 ? 181.126 128.093 102.848 1.00 103.97 ? 240 GLU D CG  1 
ATOM   15941 C CD  . GLU D 1 240 ? 182.516 127.456 102.709 1.00 106.97 ? 240 GLU D CD  1 
ATOM   15942 O OE1 . GLU D 1 240 ? 183.163 127.174 103.741 1.00 103.77 ? 240 GLU D OE1 1 
ATOM   15943 O OE2 . GLU D 1 240 ? 182.976 127.253 101.565 1.00 105.08 ? 240 GLU D OE2 1 
ATOM   15944 N N   . ALA D 1 241 ? 179.853 132.569 104.000 1.00 92.00  ? 241 ALA D N   1 
ATOM   15945 C CA  . ALA D 1 241 ? 180.160 133.886 104.560 1.00 88.39  ? 241 ALA D CA  1 
ATOM   15946 C C   . ALA D 1 241 ? 179.291 134.230 105.776 1.00 88.54  ? 241 ALA D C   1 
ATOM   15947 O O   . ALA D 1 241 ? 178.108 133.896 105.829 1.00 91.13  ? 241 ALA D O   1 
ATOM   15948 C CB  . ALA D 1 241 ? 180.022 134.946 103.471 1.00 87.38  ? 241 ALA D CB  1 
ATOM   15949 N N   . THR D 1 242 ? 179.873 134.938 106.744 1.00 82.95  ? 242 THR D N   1 
ATOM   15950 C CA  . THR D 1 242 ? 179.265 135.211 108.052 1.00 85.09  ? 242 THR D CA  1 
ATOM   15951 C C   . THR D 1 242 ? 179.266 136.689 108.424 1.00 91.34  ? 242 THR D C   1 
ATOM   15952 O O   . THR D 1 242 ? 180.218 137.411 108.141 1.00 89.94  ? 242 THR D O   1 
ATOM   15953 C CB  . THR D 1 242 ? 179.983 134.437 109.162 1.00 85.26  ? 242 THR D CB  1 
ATOM   15954 O OG1 . THR D 1 242 ? 181.350 134.776 109.221 1.00 90.68  ? 242 THR D OG1 1 
ATOM   15955 C CG2 . THR D 1 242 ? 179.894 132.926 109.011 1.00 86.22  ? 242 THR D CG2 1 
ATOM   15956 N N   . ASP D 1 243 ? 178.228 137.133 109.128 1.00 81.71  ? 243 ASP D N   1 
ATOM   15957 C CA  . ASP D 1 243 ? 178.172 138.462 109.737 1.00 73.84  ? 243 ASP D CA  1 
ATOM   15958 C C   . ASP D 1 243 ? 179.031 138.602 111.022 1.00 79.08  ? 243 ASP D C   1 
ATOM   15959 O O   . ASP D 1 243 ? 179.773 137.691 111.391 1.00 80.19  ? 243 ASP D O   1 
ATOM   15960 C CB  . ASP D 1 243 ? 176.699 138.833 109.937 1.00 78.49  ? 243 ASP D CB  1 
ATOM   15961 C CG  . ASP D 1 243 ? 175.972 138.277 111.159 1.00 82.11  ? 243 ASP D CG  1 
ATOM   15962 O OD1 . ASP D 1 243 ? 176.604 137.576 111.971 1.00 88.38  ? 243 ASP D OD1 1 
ATOM   15963 O OD2 . ASP D 1 243 ? 174.765 138.572 111.293 1.00 88.00  ? 243 ASP D OD2 1 
ATOM   15964 N N   . SER D 1 244 ? 178.950 139.739 111.723 1.00 90.34  ? 244 SER D N   1 
ATOM   15965 C CA  . SER D 1 244 ? 179.689 139.998 112.973 1.00 90.42  ? 244 SER D CA  1 
ATOM   15966 C C   . SER D 1 244 ? 179.331 139.083 114.148 1.00 87.38  ? 244 SER D C   1 
ATOM   15967 O O   . SER D 1 244 ? 180.138 138.950 115.067 1.00 85.83  ? 244 SER D O   1 
ATOM   15968 C CB  . SER D 1 244 ? 179.472 141.443 113.433 1.00 88.89  ? 244 SER D CB  1 
ATOM   15969 O OG  . SER D 1 244 ? 178.157 141.662 113.889 1.00 90.21  ? 244 SER D OG  1 
ATOM   15970 N N   . LEU D 1 245 ? 178.162 138.441 114.145 1.00 79.85  ? 245 LEU D N   1 
ATOM   15971 C CA  . LEU D 1 245 ? 177.753 137.424 115.121 1.00 80.26  ? 245 LEU D CA  1 
ATOM   15972 C C   . LEU D 1 245 ? 178.163 136.011 114.682 1.00 83.37  ? 245 LEU D C   1 
ATOM   15973 O O   . LEU D 1 245 ? 177.885 135.038 115.380 1.00 85.23  ? 245 LEU D O   1 
ATOM   15974 C CB  . LEU D 1 245 ? 176.230 137.477 115.342 1.00 83.81  ? 245 LEU D CB  1 
ATOM   15975 C CG  . LEU D 1 245 ? 175.651 138.843 115.727 1.00 86.52  ? 245 LEU D CG  1 
ATOM   15976 C CD1 . LEU D 1 245 ? 174.140 138.714 115.903 1.00 82.97  ? 245 LEU D CD1 1 
ATOM   15977 C CD2 . LEU D 1 245 ? 176.251 139.368 117.029 1.00 84.76  ? 245 LEU D CD2 1 
ATOM   15978 N N   . GLY D 1 246 ? 178.781 135.872 113.510 1.00 81.20  ? 246 GLY D N   1 
ATOM   15979 C CA  . GLY D 1 246 ? 179.086 134.596 112.881 1.00 71.44  ? 246 GLY D CA  1 
ATOM   15980 C C   . GLY D 1 246 ? 177.893 133.969 112.159 1.00 73.50  ? 246 GLY D C   1 
ATOM   15981 O O   . GLY D 1 246 ? 177.997 132.838 111.701 1.00 83.55  ? 246 GLY D O   1 
ATOM   15982 N N   . ASN D 1 247 ? 176.754 134.654 112.046 1.00 71.61  ? 247 ASN D N   1 
ATOM   15983 C CA  . ASN D 1 247 ? 175.569 134.121 111.390 1.00 67.02  ? 247 ASN D CA  1 
ATOM   15984 C C   . ASN D 1 247 ? 175.785 134.027 109.876 1.00 73.09  ? 247 ASN D C   1 
ATOM   15985 O O   . ASN D 1 247 ? 176.122 135.006 109.219 1.00 74.88  ? 247 ASN D O   1 
ATOM   15986 C CB  . ASN D 1 247 ? 174.342 134.977 111.744 1.00 63.32  ? 247 ASN D CB  1 
ATOM   15987 C CG  . ASN D 1 247 ? 173.785 134.711 113.125 1.00 69.90  ? 247 ASN D CG  1 
ATOM   15988 O OD1 . ASN D 1 247 ? 174.144 133.774 113.806 1.00 78.84  ? 247 ASN D OD1 1 
ATOM   15989 N ND2 . ASN D 1 247 ? 172.851 135.498 113.579 1.00 75.50  ? 247 ASN D ND2 1 
ATOM   15990 N N   . THR D 1 248 ? 175.554 132.842 109.321 1.00 81.91  ? 248 THR D N   1 
ATOM   15991 C CA  . THR D 1 248 ? 175.423 132.578 107.881 1.00 78.55  ? 248 THR D CA  1 
ATOM   15992 C C   . THR D 1 248 ? 174.019 132.987 107.412 1.00 74.39  ? 248 THR D C   1 
ATOM   15993 O O   . THR D 1 248 ? 173.149 133.246 108.241 1.00 75.25  ? 248 THR D O   1 
ATOM   15994 C CB  . THR D 1 248 ? 175.715 131.081 107.642 1.00 80.79  ? 248 THR D CB  1 
ATOM   15995 O OG1 . THR D 1 248 ? 177.004 130.778 108.110 1.00 75.16  ? 248 THR D OG1 1 
ATOM   15996 C CG2 . THR D 1 248 ? 175.693 130.636 106.194 1.00 82.91  ? 248 THR D CG2 1 
ATOM   15997 N N   . VAL D 1 249 ? 173.722 133.019 106.114 1.00 62.90  ? 249 VAL D N   1 
ATOM   15998 C CA  . VAL D 1 249 ? 172.373 133.352 105.604 1.00 65.71  ? 249 VAL D CA  1 
ATOM   15999 C C   . VAL D 1 249 ? 171.256 132.471 106.187 1.00 72.87  ? 249 VAL D C   1 
ATOM   16000 O O   . VAL D 1 249 ? 170.138 132.937 106.370 1.00 81.07  ? 249 VAL D O   1 
ATOM   16001 C CB  . VAL D 1 249 ? 172.350 133.376 104.063 1.00 64.51  ? 249 VAL D CB  1 
ATOM   16002 C CG1 . VAL D 1 249 ? 172.694 132.045 103.404 1.00 71.51  ? 249 VAL D CG1 1 
ATOM   16003 C CG2 . VAL D 1 249 ? 170.987 133.813 103.538 1.00 67.79  ? 249 VAL D CG2 1 
ATOM   16004 N N   . LEU D 1 250 ? 171.560 131.226 106.566 1.00 71.29  ? 250 LEU D N   1 
ATOM   16005 C CA  . LEU D 1 250 ? 170.613 130.300 107.187 1.00 63.40  ? 250 LEU D CA  1 
ATOM   16006 C C   . LEU D 1 250 ? 170.333 130.641 108.659 1.00 66.69  ? 250 LEU D C   1 
ATOM   16007 O O   . LEU D 1 250 ? 169.196 130.524 109.099 1.00 70.71  ? 250 LEU D O   1 
ATOM   16008 C CB  . LEU D 1 250 ? 171.114 128.856 107.011 1.00 70.30  ? 250 LEU D CB  1 
ATOM   16009 C CG  . LEU D 1 250 ? 171.284 128.366 105.561 1.00 64.05  ? 250 LEU D CG  1 
ATOM   16010 C CD1 . LEU D 1 250 ? 171.722 126.910 105.568 1.00 68.54  ? 250 LEU D CD1 1 
ATOM   16011 C CD2 . LEU D 1 250 ? 170.000 128.464 104.746 1.00 65.55  ? 250 LEU D CD2 1 
ATOM   16012 N N   . HIS D 1 251 ? 171.320 131.141 109.394 1.00 65.41  ? 251 HIS D N   1 
ATOM   16013 C CA  . HIS D 1 251 ? 171.080 131.736 110.697 1.00 62.50  ? 251 HIS D CA  1 
ATOM   16014 C C   . HIS D 1 251 ? 170.299 133.042 110.578 1.00 71.34  ? 251 HIS D C   1 
ATOM   16015 O O   . HIS D 1 251 ? 169.418 133.295 111.388 1.00 80.41  ? 251 HIS D O   1 
ATOM   16016 C CB  . HIS D 1 251 ? 172.403 132.013 111.394 1.00 71.17  ? 251 HIS D CB  1 
ATOM   16017 C CG  . HIS D 1 251 ? 173.339 130.854 111.549 1.00 67.08  ? 251 HIS D CG  1 
ATOM   16018 N ND1 . HIS D 1 251 ? 174.286 130.461 110.611 1.00 61.43  ? 251 HIS D ND1 1 
ATOM   16019 C CD2 . HIS D 1 251 ? 173.510 130.125 112.679 1.00 63.84  ? 251 HIS D CD2 1 
ATOM   16020 C CE1 . HIS D 1 251 ? 175.009 129.501 111.191 1.00 63.24  ? 251 HIS D CE1 1 
ATOM   16021 N NE2 . HIS D 1 251 ? 174.566 129.289 112.433 1.00 68.48  ? 251 HIS D NE2 1 
ATOM   16022 N N   . ALA D 1 252 ? 170.581 133.862 109.565 1.00 63.39  ? 252 ALA D N   1 
ATOM   16023 C CA  . ALA D 1 252 ? 169.849 135.099 109.321 1.00 56.92  ? 252 ALA D CA  1 
ATOM   16024 C C   . ALA D 1 252 ? 168.368 134.836 109.037 1.00 61.20  ? 252 ALA D C   1 
ATOM   16025 O O   . ALA D 1 252 ? 167.516 135.431 109.686 1.00 74.16  ? 252 ALA D O   1 
ATOM   16026 C CB  . ALA D 1 252 ? 170.525 135.880 108.196 1.00 57.80  ? 252 ALA D CB  1 
ATOM   16027 N N   . LEU D 1 253 ? 168.031 133.882 108.171 1.00 66.34  ? 253 LEU D N   1 
ATOM   16028 C CA  . LEU D 1 253 ? 166.646 133.467 107.929 1.00 59.45  ? 253 LEU D CA  1 
ATOM   16029 C C   . LEU D 1 253 ? 165.956 132.907 109.175 1.00 54.46  ? 253 LEU D C   1 
ATOM   16030 O O   . LEU D 1 253 ? 164.794 133.206 109.413 1.00 63.43  ? 253 LEU D O   1 
ATOM   16031 C CB  . LEU D 1 253 ? 166.622 132.431 106.804 1.00 60.41  ? 253 LEU D CB  1 
ATOM   16032 C CG  . LEU D 1 253 ? 166.788 133.049 105.416 1.00 60.40  ? 253 LEU D CG  1 
ATOM   16033 C CD1 . LEU D 1 253 ? 166.997 131.933 104.413 1.00 65.56  ? 253 LEU D CD1 1 
ATOM   16034 C CD2 . LEU D 1 253 ? 165.550 133.823 104.970 1.00 63.82  ? 253 LEU D CD2 1 
ATOM   16035 N N   . VAL D 1 254 ? 166.657 132.162 110.027 1.00 63.22  ? 254 VAL D N   1 
ATOM   16036 C CA  . VAL D 1 254 ? 166.111 131.718 111.320 1.00 62.49  ? 254 VAL D CA  1 
ATOM   16037 C C   . VAL D 1 254 ? 165.873 132.896 112.267 1.00 63.46  ? 254 VAL D C   1 
ATOM   16038 O O   . VAL D 1 254 ? 164.848 132.944 112.945 1.00 73.90  ? 254 VAL D O   1 
ATOM   16039 C CB  . VAL D 1 254 ? 167.029 130.654 111.933 1.00 67.15  ? 254 VAL D CB  1 
ATOM   16040 C CG1 . VAL D 1 254 ? 166.690 130.366 113.387 1.00 73.00  ? 254 VAL D CG1 1 
ATOM   16041 C CG2 . VAL D 1 254 ? 166.899 129.337 111.168 1.00 64.15  ? 254 VAL D CG2 1 
ATOM   16042 N N   . MET D 1 255 ? 166.753 133.896 112.301 1.00 67.69  ? 255 MET D N   1 
ATOM   16043 C CA  . MET D 1 255 ? 166.557 135.105 113.112 1.00 65.98  ? 255 MET D CA  1 
ATOM   16044 C C   . MET D 1 255 ? 165.324 135.907 112.684 1.00 69.56  ? 255 MET D C   1 
ATOM   16045 O O   . MET D 1 255 ? 164.643 136.483 113.526 1.00 73.49  ? 255 MET D O   1 
ATOM   16046 C CB  . MET D 1 255 ? 167.796 136.003 113.037 1.00 65.07  ? 255 MET D CB  1 
ATOM   16047 C CG  . MET D 1 255 ? 168.938 135.498 113.906 1.00 61.67  ? 255 MET D CG  1 
ATOM   16048 S SD  . MET D 1 255 ? 168.587 135.619 115.677 1.00 79.34  ? 255 MET D SD  1 
ATOM   16049 C CE  . MET D 1 255 ? 170.279 135.696 116.308 1.00 69.47  ? 255 MET D CE  1 
ATOM   16050 N N   . ILE D 1 256 ? 165.005 135.895 111.395 1.00 77.73  ? 256 ILE D N   1 
ATOM   16051 C CA  . ILE D 1 256 ? 163.956 136.699 110.747 1.00 72.38  ? 256 ILE D CA  1 
ATOM   16052 C C   . ILE D 1 256 ? 162.614 135.977 110.614 1.00 75.84  ? 256 ILE D C   1 
ATOM   16053 O O   . ILE D 1 256 ? 161.591 136.615 110.371 1.00 80.29  ? 256 ILE D O   1 
ATOM   16054 C CB  . ILE D 1 256 ? 164.559 137.185 109.421 1.00 72.64  ? 256 ILE D CB  1 
ATOM   16055 C CG1 . ILE D 1 256 ? 165.498 138.335 109.825 1.00 75.38  ? 256 ILE D CG1 1 
ATOM   16056 C CG2 . ILE D 1 256 ? 163.581 137.614 108.333 1.00 69.78  ? 256 ILE D CG2 1 
ATOM   16057 C CD1 . ILE D 1 256 ? 166.639 138.538 108.859 1.00 75.53  ? 256 ILE D CD1 1 
ATOM   16058 N N   . ALA D 1 257 ? 162.579 134.668 110.848 1.00 77.53  ? 257 ALA D N   1 
ATOM   16059 C CA  . ALA D 1 257 ? 161.337 133.921 110.935 1.00 74.31  ? 257 ALA D CA  1 
ATOM   16060 C C   . ALA D 1 257 ? 160.433 134.466 112.051 1.00 78.91  ? 257 ALA D C   1 
ATOM   16061 O O   . ALA D 1 257 ? 160.868 134.614 113.189 1.00 82.87  ? 257 ALA D O   1 
ATOM   16062 C CB  . ALA D 1 257 ? 161.664 132.447 111.156 1.00 75.42  ? 257 ALA D CB  1 
ATOM   16063 N N   . ASP D 1 258 ? 159.161 134.678 111.750 1.00 97.99  ? 258 ASP D N   1 
ATOM   16064 C CA  . ASP D 1 258 ? 158.070 134.886 112.699 1.00 99.80  ? 258 ASP D CA  1 
ATOM   16065 C C   . ASP D 1 258 ? 157.089 133.723 112.542 1.00 105.01 ? 258 ASP D C   1 
ATOM   16066 O O   . ASP D 1 258 ? 156.946 133.152 111.461 1.00 105.93 ? 258 ASP D O   1 
ATOM   16067 C CB  . ASP D 1 258 ? 157.348 136.221 112.458 1.00 101.45 ? 258 ASP D CB  1 
ATOM   16068 C CG  . ASP D 1 258 ? 158.108 137.457 112.951 1.00 107.18 ? 258 ASP D CG  1 
ATOM   16069 O OD1 . ASP D 1 258 ? 158.963 137.335 113.851 1.00 108.56 ? 258 ASP D OD1 1 
ATOM   16070 O OD2 . ASP D 1 258 ? 157.777 138.572 112.496 1.00 104.13 ? 258 ASP D OD2 1 
ATOM   16071 N N   . ASN D 1 259 ? 156.410 133.340 113.614 1.00 101.43 ? 259 ASN D N   1 
ATOM   16072 C CA  . ASN D 1 259 ? 155.600 132.122 113.627 1.00 103.46 ? 259 ASN D CA  1 
ATOM   16073 C C   . ASN D 1 259 ? 154.229 132.278 112.929 1.00 104.57 ? 259 ASN D C   1 
ATOM   16074 O O   . ASN D 1 259 ? 153.355 131.427 113.075 1.00 104.00 ? 259 ASN D O   1 
ATOM   16075 C CB  . ASN D 1 259 ? 155.524 131.599 115.069 1.00 101.81 ? 259 ASN D CB  1 
ATOM   16076 C CG  . ASN D 1 259 ? 156.902 131.424 115.683 1.00 98.20  ? 259 ASN D CG  1 
ATOM   16077 O OD1 . ASN D 1 259 ? 157.725 130.657 115.214 1.00 94.50  ? 259 ASN D OD1 1 
ATOM   16078 N ND2 . ASN D 1 259 ? 157.211 132.152 116.731 1.00 99.37  ? 259 ASN D ND2 1 
ATOM   16079 N N   . SER D 1 260 ? 154.015 133.360 112.173 1.00 106.87 ? 260 SER D N   1 
ATOM   16080 C CA  . SER D 1 260 ? 152.826 133.570 111.344 1.00 106.29 ? 260 SER D CA  1 
ATOM   16081 C C   . SER D 1 260 ? 152.893 132.731 110.060 1.00 105.46 ? 260 SER D C   1 
ATOM   16082 O O   . SER D 1 260 ? 153.984 132.434 109.569 1.00 106.21 ? 260 SER D O   1 
ATOM   16083 C CB  . SER D 1 260 ? 152.671 135.061 111.026 1.00 106.59 ? 260 SER D CB  1 
ATOM   16084 O OG  . SER D 1 260 ? 153.753 135.533 110.250 1.00 105.89 ? 260 SER D OG  1 
ATOM   16085 N N   . PRO D 1 261 ? 151.755 132.328 109.468 1.00 109.40 ? 261 PRO D N   1 
ATOM   16086 C CA  . PRO D 1 261 ? 151.759 131.419 108.321 1.00 111.20 ? 261 PRO D CA  1 
ATOM   16087 C C   . PRO D 1 261 ? 152.330 132.058 107.049 1.00 108.89 ? 261 PRO D C   1 
ATOM   16088 O O   . PRO D 1 261 ? 152.918 131.363 106.229 1.00 102.36 ? 261 PRO D O   1 
ATOM   16089 C CB  . PRO D 1 261 ? 150.303 130.987 108.145 1.00 109.67 ? 261 PRO D CB  1 
ATOM   16090 C CG  . PRO D 1 261 ? 149.501 132.127 108.764 1.00 106.65 ? 261 PRO D CG  1 
ATOM   16091 C CD  . PRO D 1 261 ? 150.397 132.594 109.905 1.00 107.01 ? 261 PRO D CD  1 
ATOM   16092 N N   . GLU D 1 262 ? 152.203 133.374 106.886 1.00 106.55 ? 262 GLU D N   1 
ATOM   16093 C CA  . GLU D 1 262 ? 152.711 134.098 105.714 1.00 108.72 ? 262 GLU D CA  1 
ATOM   16094 C C   . GLU D 1 262 ? 154.233 134.272 105.748 1.00 111.14 ? 262 GLU D C   1 
ATOM   16095 O O   . GLU D 1 262 ? 154.905 133.994 104.756 1.00 110.11 ? 262 GLU D O   1 
ATOM   16096 C CB  . GLU D 1 262 ? 152.016 135.465 105.603 1.00 104.30 ? 262 GLU D CB  1 
ATOM   16097 N N   . ASN D 1 263 ? 154.805 134.681 106.882 1.00 98.28  ? 263 ASN D N   1 
ATOM   16098 C CA  . ASN D 1 263 ? 156.257 134.785 107.032 1.00 94.80  ? 263 ASN D CA  1 
ATOM   16099 C C   . ASN D 1 263 ? 156.900 133.398 106.984 1.00 100.69 ? 263 ASN D C   1 
ATOM   16100 O O   . ASN D 1 263 ? 157.762 133.148 106.145 1.00 101.17 ? 263 ASN D O   1 
ATOM   16101 C CB  . ASN D 1 263 ? 156.583 135.539 108.330 1.00 97.16  ? 263 ASN D CB  1 
ATOM   16102 C CG  . ASN D 1 263 ? 158.068 135.582 108.641 1.00 97.70  ? 263 ASN D CG  1 
ATOM   16103 O OD1 . ASN D 1 263 ? 158.671 134.575 108.956 1.00 100.84 ? 263 ASN D OD1 1 
ATOM   16104 N ND2 . ASN D 1 263 ? 158.701 136.720 108.604 1.00 95.96  ? 263 ASN D ND2 1 
ATOM   16105 N N   . SER D 1 264 ? 156.467 132.476 107.848 1.00 97.85  ? 264 SER D N   1 
ATOM   16106 C CA  . SER D 1 264 ? 157.141 131.186 107.997 1.00 90.45  ? 264 SER D CA  1 
ATOM   16107 C C   . SER D 1 264 ? 157.125 130.364 106.716 1.00 90.04  ? 264 SER D C   1 
ATOM   16108 O O   . SER D 1 264 ? 158.171 129.840 106.351 1.00 95.19  ? 264 SER D O   1 
ATOM   16109 C CB  . SER D 1 264 ? 156.561 130.383 109.156 1.00 92.08  ? 264 SER D CB  1 
ATOM   16110 O OG  . SER D 1 264 ? 155.188 130.133 108.971 1.00 96.92  ? 264 SER D OG  1 
ATOM   16111 N N   . ALA D 1 265 ? 156.023 130.302 105.964 1.00 96.79  ? 265 ALA D N   1 
ATOM   16112 C CA  . ALA D 1 265 ? 155.992 129.572 104.696 1.00 96.00  ? 265 ALA D CA  1 
ATOM   16113 C C   . ALA D 1 265 ? 156.989 130.130 103.675 1.00 95.18  ? 265 ALA D C   1 
ATOM   16114 O O   . ALA D 1 265 ? 157.668 129.366 102.994 1.00 91.71  ? 265 ALA D O   1 
ATOM   16115 C CB  . ALA D 1 265 ? 154.573 129.602 104.139 1.00 95.92  ? 265 ALA D CB  1 
ATOM   16116 N N   . LEU D 1 266 ? 157.137 131.453 103.587 1.00 94.03  ? 266 LEU D N   1 
ATOM   16117 C CA  . LEU D 1 266 ? 158.073 132.086 102.660 1.00 95.89  ? 266 LEU D CA  1 
ATOM   16118 C C   . LEU D 1 266 ? 159.534 131.989 103.125 1.00 94.82  ? 266 LEU D C   1 
ATOM   16119 O O   . LEU D 1 266 ? 160.414 131.788 102.300 1.00 92.68  ? 266 LEU D O   1 
ATOM   16120 C CB  . LEU D 1 266 ? 157.642 133.538 102.418 1.00 95.50  ? 266 LEU D CB  1 
ATOM   16121 C CG  . LEU D 1 266 ? 156.288 133.691 101.698 1.00 99.04  ? 266 LEU D CG  1 
ATOM   16122 C CD1 . LEU D 1 266 ? 155.912 135.166 101.616 1.00 95.37  ? 266 LEU D CD1 1 
ATOM   16123 C CD2 . LEU D 1 266 ? 156.323 133.145 100.273 1.00 95.33  ? 266 LEU D CD2 1 
ATOM   16124 N N   . VAL D 1 267 ? 159.808 132.048 104.433 1.00 88.41  ? 267 VAL D N   1 
ATOM   16125 C CA  . VAL D 1 267 ? 161.145 131.768 104.994 1.00 86.31  ? 267 VAL D CA  1 
ATOM   16126 C C   . VAL D 1 267 ? 161.547 130.313 104.770 1.00 83.60  ? 267 VAL D C   1 
ATOM   16127 O O   . VAL D 1 267 ? 162.689 130.058 104.419 1.00 85.44  ? 267 VAL D O   1 
ATOM   16128 C CB  . VAL D 1 267 ? 161.219 132.130 106.485 1.00 79.39  ? 267 VAL D CB  1 
ATOM   16129 C CG1 . VAL D 1 267 ? 162.508 131.645 107.148 1.00 81.05  ? 267 VAL D CG1 1 
ATOM   16130 C CG2 . VAL D 1 267 ? 161.175 133.648 106.652 1.00 84.91  ? 267 VAL D CG2 1 
ATOM   16131 N N   . ILE D 1 268 ? 160.627 129.362 104.912 1.00 78.98  ? 268 ILE D N   1 
ATOM   16132 C CA  . ILE D 1 268 ? 160.857 127.941 104.641 1.00 73.75  ? 268 ILE D CA  1 
ATOM   16133 C C   . ILE D 1 268 ? 161.238 127.708 103.174 1.00 81.37  ? 268 ILE D C   1 
ATOM   16134 O O   . ILE D 1 268 ? 162.196 126.997 102.897 1.00 84.20  ? 268 ILE D O   1 
ATOM   16135 C CB  . ILE D 1 268 ? 159.610 127.148 105.080 1.00 79.17  ? 268 ILE D CB  1 
ATOM   16136 C CG1 . ILE D 1 268 ? 159.652 126.970 106.611 1.00 74.90  ? 268 ILE D CG1 1 
ATOM   16137 C CG2 . ILE D 1 268 ? 159.481 125.799 104.369 1.00 81.25  ? 268 ILE D CG2 1 
ATOM   16138 C CD1 . ILE D 1 268 ? 158.315 126.538 107.215 1.00 76.43  ? 268 ILE D CD1 1 
ATOM   16139 N N   . HIS D 1 269 ? 160.560 128.354 102.223 1.00 94.96  ? 269 HIS D N   1 
ATOM   16140 C CA  . HIS D 1 269 ? 160.945 128.278 100.812 1.00 92.26  ? 269 HIS D CA  1 
ATOM   16141 C C   . HIS D 1 269 ? 162.310 128.912 100.544 1.00 89.43  ? 269 HIS D C   1 
ATOM   16142 O O   . HIS D 1 269 ? 163.133 128.325 99.849  1.00 89.89  ? 269 HIS D O   1 
ATOM   16143 C CB  . HIS D 1 269 ? 159.873 128.920 99.926  1.00 88.74  ? 269 HIS D CB  1 
ATOM   16144 C CG  . HIS D 1 269 ? 158.662 128.045 99.754  1.00 95.88  ? 269 HIS D CG  1 
ATOM   16145 N ND1 . HIS D 1 269 ? 157.668 127.827 100.676 1.00 98.33  ? 269 HIS D ND1 1 
ATOM   16146 C CD2 . HIS D 1 269 ? 158.418 127.203 98.710  1.00 96.27  ? 269 HIS D CD2 1 
ATOM   16147 C CE1 . HIS D 1 269 ? 156.835 126.892 100.196 1.00 97.81  ? 269 HIS D CE1 1 
ATOM   16148 N NE2 . HIS D 1 269 ? 157.255 126.478 98.992  1.00 97.81  ? 269 HIS D NE2 1 
ATOM   16149 N N   . MET D 1 270 ? 162.574 130.090 101.109 1.00 85.31  ? 270 MET D N   1 
ATOM   16150 C CA  . MET D 1 270 ? 163.857 130.775 100.963 1.00 82.46  ? 270 MET D CA  1 
ATOM   16151 C C   . MET D 1 270 ? 165.015 129.964 101.552 1.00 82.81  ? 270 MET D C   1 
ATOM   16152 O O   . MET D 1 270 ? 166.062 129.836 100.926 1.00 82.60  ? 270 MET D O   1 
ATOM   16153 C CB  . MET D 1 270 ? 163.742 132.161 101.595 1.00 79.32  ? 270 MET D CB  1 
ATOM   16154 C CG  . MET D 1 270 ? 164.881 133.088 101.188 1.00 83.59  ? 270 MET D CG  1 
ATOM   16155 S SD  . MET D 1 270 ? 164.797 133.691 99.484  1.00 81.19  ? 270 MET D SD  1 
ATOM   16156 C CE  . MET D 1 270 ? 166.279 132.903 98.841  1.00 88.79  ? 270 MET D CE  1 
ATOM   16157 N N   . TYR D 1 271 ? 164.813 129.347 102.714 1.00 81.71  ? 271 TYR D N   1 
ATOM   16158 C CA  . TYR D 1 271 ? 165.779 128.471 103.368 1.00 77.50  ? 271 TYR D CA  1 
ATOM   16159 C C   . TYR D 1 271 ? 166.071 127.219 102.531 1.00 78.91  ? 271 TYR D C   1 
ATOM   16160 O O   . TYR D 1 271 ? 167.226 126.919 102.251 1.00 78.22  ? 271 TYR D O   1 
ATOM   16161 C CB  . TYR D 1 271 ? 165.221 128.117 104.752 1.00 79.14  ? 271 TYR D CB  1 
ATOM   16162 C CG  . TYR D 1 271 ? 166.182 127.399 105.669 1.00 75.78  ? 271 TYR D CG  1 
ATOM   16163 C CD1 . TYR D 1 271 ? 166.513 126.053 105.440 1.00 72.86  ? 271 TYR D CD1 1 
ATOM   16164 C CD2 . TYR D 1 271 ? 166.742 128.082 106.764 1.00 75.64  ? 271 TYR D CD2 1 
ATOM   16165 C CE1 . TYR D 1 271 ? 167.435 125.405 106.273 1.00 75.68  ? 271 TYR D CE1 1 
ATOM   16166 C CE2 . TYR D 1 271 ? 167.643 127.425 107.616 1.00 76.79  ? 271 TYR D CE2 1 
ATOM   16167 C CZ  . TYR D 1 271 ? 167.998 126.088 107.364 1.00 80.94  ? 271 TYR D CZ  1 
ATOM   16168 O OH  . TYR D 1 271 ? 168.869 125.455 108.182 1.00 79.16  ? 271 TYR D OH  1 
ATOM   16169 N N   . ASP D 1 272 ? 165.037 126.504 102.084 1.00 83.27  ? 272 ASP D N   1 
ATOM   16170 C CA  . ASP D 1 272 ? 165.185 125.298 101.270 1.00 80.53  ? 272 ASP D CA  1 
ATOM   16171 C C   . ASP D 1 272 ? 165.901 125.556 99.950  1.00 88.88  ? 272 ASP D C   1 
ATOM   16172 O O   . ASP D 1 272 ? 166.807 124.805 99.603  1.00 91.18  ? 272 ASP D O   1 
ATOM   16173 C CB  . ASP D 1 272 ? 163.819 124.682 100.962 1.00 86.28  ? 272 ASP D CB  1 
ATOM   16174 C CG  . ASP D 1 272 ? 163.214 123.894 102.119 1.00 93.60  ? 272 ASP D CG  1 
ATOM   16175 O OD1 . ASP D 1 272 ? 163.905 123.659 103.132 1.00 94.12  ? 272 ASP D OD1 1 
ATOM   16176 O OD2 . ASP D 1 272 ? 162.063 123.430 101.969 1.00 93.96  ? 272 ASP D OD2 1 
ATOM   16177 N N   . GLY D 1 273 ? 165.546 126.602 99.202  1.00 86.29  ? 273 GLY D N   1 
ATOM   16178 C CA  . GLY D 1 273 ? 166.233 126.876 97.941  1.00 77.94  ? 273 GLY D CA  1 
ATOM   16179 C C   . GLY D 1 273 ? 167.695 127.281 98.128  1.00 81.71  ? 273 GLY D C   1 
ATOM   16180 O O   . GLY D 1 273 ? 168.529 126.896 97.317  1.00 82.01  ? 273 GLY D O   1 
ATOM   16181 N N   . LEU D 1 274 ? 168.055 127.990 99.200  1.00 85.75  ? 274 LEU D N   1 
ATOM   16182 C CA  . LEU D 1 274 ? 169.457 128.270 99.520  1.00 84.59  ? 274 LEU D CA  1 
ATOM   16183 C C   . LEU D 1 274 ? 170.220 127.011 99.918  1.00 85.15  ? 274 LEU D C   1 
ATOM   16184 O O   . LEU D 1 274 ? 171.327 126.792 99.441  1.00 87.11  ? 274 LEU D O   1 
ATOM   16185 C CB  . LEU D 1 274 ? 169.539 129.275 100.672 1.00 84.30  ? 274 LEU D CB  1 
ATOM   16186 C CG  . LEU D 1 274 ? 169.183 130.710 100.287 1.00 79.88  ? 274 LEU D CG  1 
ATOM   16187 C CD1 . LEU D 1 274 ? 169.097 131.515 101.567 1.00 84.99  ? 274 LEU D CD1 1 
ATOM   16188 C CD2 . LEU D 1 274 ? 170.243 131.351 99.402  1.00 78.03  ? 274 LEU D CD2 1 
ATOM   16189 N N   . LEU D 1 275 ? 169.602 126.115 100.681 1.00 85.61  ? 275 LEU D N   1 
ATOM   16190 C CA  . LEU D 1 275 ? 170.179 124.821 101.026 1.00 83.56  ? 275 LEU D CA  1 
ATOM   16191 C C   . LEU D 1 275 ? 170.363 123.911 99.797  1.00 77.98  ? 275 LEU D C   1 
ATOM   16192 O O   . LEU D 1 275 ? 171.436 123.349 99.604  1.00 78.79  ? 275 LEU D O   1 
ATOM   16193 C CB  . LEU D 1 275 ? 169.272 124.192 102.088 1.00 80.71  ? 275 LEU D CB  1 
ATOM   16194 C CG  . LEU D 1 275 ? 169.852 122.932 102.717 1.00 78.82  ? 275 LEU D CG  1 
ATOM   16195 C CD1 . LEU D 1 275 ? 171.026 123.240 103.628 1.00 77.62  ? 275 LEU D CD1 1 
ATOM   16196 C CD2 . LEU D 1 275 ? 168.765 122.265 103.523 1.00 80.66  ? 275 LEU D CD2 1 
ATOM   16197 N N   . GLN D 1 276 ? 169.360 123.822 98.922  1.00 86.32  ? 276 GLN D N   1 
ATOM   16198 C CA  . GLN D 1 276 ? 169.460 123.137 97.632  1.00 85.04  ? 276 GLN D CA  1 
ATOM   16199 C C   . GLN D 1 276 ? 170.511 123.773 96.714  1.00 93.02  ? 276 GLN D C   1 
ATOM   16200 O O   . GLN D 1 276 ? 171.227 123.054 96.023  1.00 95.58  ? 276 GLN D O   1 
ATOM   16201 C CB  . GLN D 1 276 ? 168.095 123.128 96.933  1.00 86.48  ? 276 GLN D CB  1 
ATOM   16202 C CG  . GLN D 1 276 ? 167.054 122.234 97.621  1.00 92.30  ? 276 GLN D CG  1 
ATOM   16203 C CD  . GLN D 1 276 ? 165.638 122.462 97.086  1.00 92.88  ? 276 GLN D CD  1 
ATOM   16204 O OE1 . GLN D 1 276 ? 165.398 123.159 96.111  1.00 92.50  ? 276 GLN D OE1 1 
ATOM   16205 N NE2 . GLN D 1 276 ? 164.636 121.875 97.698  1.00 89.68  ? 276 GLN D NE2 1 
ATOM   16206 N N   . MET D 1 277 ? 170.678 125.101 96.714  1.00 101.83 ? 277 MET D N   1 
ATOM   16207 C CA  . MET D 1 277 ? 171.765 125.757 95.969  1.00 97.73  ? 277 MET D CA  1 
ATOM   16208 C C   . MET D 1 277 ? 173.142 125.503 96.588  1.00 99.00  ? 277 MET D C   1 
ATOM   16209 O O   . MET D 1 277 ? 174.106 125.302 95.857  1.00 97.69  ? 277 MET D O   1 
ATOM   16210 C CB  . MET D 1 277 ? 171.506 127.261 95.826  1.00 98.08  ? 277 MET D CB  1 
ATOM   16211 C CG  . MET D 1 277 ? 170.502 127.519 94.704  1.00 100.62 ? 277 MET D CG  1 
ATOM   16212 S SD  . MET D 1 277 ? 170.282 129.251 94.231  1.00 103.42 ? 277 MET D SD  1 
ATOM   16213 C CE  . MET D 1 277 ? 169.097 129.760 95.495  1.00 99.26  ? 277 MET D CE  1 
ATOM   16214 N N   . GLY D 1 278 ? 173.256 125.398 97.909  1.00 101.70 ? 278 GLY D N   1 
ATOM   16215 C CA  . GLY D 1 278 ? 174.476 124.942 98.571  1.00 104.06 ? 278 GLY D CA  1 
ATOM   16216 C C   . GLY D 1 278 ? 174.956 123.571 98.090  1.00 100.65 ? 278 GLY D C   1 
ATOM   16217 O O   . GLY D 1 278 ? 176.155 123.373 97.935  1.00 98.30  ? 278 GLY D O   1 
ATOM   16218 N N   . ALA D 1 279 ? 174.053 122.649 97.747  1.00 101.03 ? 279 ALA D N   1 
ATOM   16219 C CA  . ALA D 1 279 ? 174.418 121.355 97.175  1.00 100.76 ? 279 ALA D CA  1 
ATOM   16220 C C   . ALA D 1 279 ? 174.984 121.447 95.744  1.00 104.13 ? 279 ALA D C   1 
ATOM   16221 O O   . ALA D 1 279 ? 175.697 120.536 95.325  1.00 103.28 ? 279 ALA D O   1 
ATOM   16222 C CB  . ALA D 1 279 ? 173.212 120.417 97.247  1.00 99.05  ? 279 ALA D CB  1 
ATOM   16223 N N   . ARG D 1 280 ? 174.716 122.531 94.993  1.00 108.06 ? 280 ARG D N   1 
ATOM   16224 C CA  . ARG D 1 280 ? 175.373 122.816 93.701  1.00 105.91 ? 280 ARG D CA  1 
ATOM   16225 C C   . ARG D 1 280 ? 176.689 123.575 93.865  1.00 104.67 ? 280 ARG D C   1 
ATOM   16226 O O   . ARG D 1 280 ? 177.701 123.205 93.278  1.00 99.73  ? 280 ARG D O   1 
ATOM   16227 C CB  . ARG D 1 280 ? 174.463 123.633 92.769  1.00 104.87 ? 280 ARG D CB  1 
ATOM   16228 C CG  . ARG D 1 280 ? 173.071 123.042 92.536  1.00 102.45 ? 280 ARG D CG  1 
ATOM   16229 C CD  . ARG D 1 280 ? 172.442 123.592 91.249  1.00 103.35 ? 280 ARG D CD  1 
ATOM   16230 N NE  . ARG D 1 280 ? 172.394 125.069 91.192  1.00 107.39 ? 280 ARG D NE  1 
ATOM   16231 C CZ  . ARG D 1 280 ? 171.345 125.844 91.360  1.00 110.61 ? 280 ARG D CZ  1 
ATOM   16232 N NH1 . ARG D 1 280 ? 171.421 127.127 91.163  1.00 107.61 ? 280 ARG D NH1 1 
ATOM   16233 N NH2 . ARG D 1 280 ? 170.194 125.369 91.735  1.00 106.77 ? 280 ARG D NH2 1 
ATOM   16234 N N   . LEU D 1 281 ? 176.653 124.663 94.631  1.00 109.29 ? 281 LEU D N   1 
ATOM   16235 C CA  . LEU D 1 281 ? 177.702 125.685 94.708  1.00 108.79 ? 281 LEU D CA  1 
ATOM   16236 C C   . LEU D 1 281 ? 178.801 125.360 95.728  1.00 107.71 ? 281 LEU D C   1 
ATOM   16237 O O   . LEU D 1 281 ? 179.951 125.747 95.539  1.00 105.76 ? 281 LEU D O   1 
ATOM   16238 C CB  . LEU D 1 281 ? 177.033 127.025 95.062  1.00 108.14 ? 281 LEU D CB  1 
ATOM   16239 C CG  . LEU D 1 281 ? 175.969 127.500 94.061  1.00 106.33 ? 281 LEU D CG  1 
ATOM   16240 C CD1 . LEU D 1 281 ? 175.231 128.692 94.642  1.00 111.03 ? 281 LEU D CD1 1 
ATOM   16241 C CD2 . LEU D 1 281 ? 176.572 127.901 92.722  1.00 100.50 ? 281 LEU D CD2 1 
ATOM   16242 N N   . CYS D 1 282 ? 178.454 124.633 96.792  1.00 109.82 ? 282 CYS D N   1 
ATOM   16243 C CA  . CYS D 1 282 ? 179.324 124.270 97.909  1.00 109.67 ? 282 CYS D CA  1 
ATOM   16244 C C   . CYS D 1 282 ? 179.182 122.765 98.239  1.00 112.90 ? 282 CYS D C   1 
ATOM   16245 O O   . CYS D 1 282 ? 178.869 122.419 99.379  1.00 115.41 ? 282 CYS D O   1 
ATOM   16246 C CB  . CYS D 1 282 ? 178.964 125.146 99.125  1.00 110.02 ? 282 CYS D CB  1 
ATOM   16247 S SG  . CYS D 1 282 ? 179.058 126.916 98.772  1.00 117.30 ? 282 CYS D SG  1 
ATOM   16248 N N   . PRO D 1 283 ? 179.358 121.838 97.277  1.00 109.16 ? 283 PRO D N   1 
ATOM   16249 C CA  . PRO D 1 283 ? 178.835 120.474 97.386  1.00 108.02 ? 283 PRO D CA  1 
ATOM   16250 C C   . PRO D 1 283 ? 179.449 119.661 98.536  1.00 107.83 ? 283 PRO D C   1 
ATOM   16251 O O   . PRO D 1 283 ? 178.792 118.781 99.091  1.00 104.75 ? 283 PRO D O   1 
ATOM   16252 C CB  . PRO D 1 283 ? 179.119 119.831 96.025  1.00 107.57 ? 283 PRO D CB  1 
ATOM   16253 C CG  . PRO D 1 283 ? 180.296 120.631 95.469  1.00 107.46 ? 283 PRO D CG  1 
ATOM   16254 C CD  . PRO D 1 283 ? 180.033 122.034 96.003  1.00 107.52 ? 283 PRO D CD  1 
ATOM   16255 N N   . THR D 1 284 ? 180.693 119.954 98.910  1.00 110.82 ? 284 THR D N   1 
ATOM   16256 C CA  . THR D 1 284 ? 181.403 119.324 100.037 1.00 112.18 ? 284 THR D CA  1 
ATOM   16257 C C   . THR D 1 284 ? 181.093 119.951 101.403 1.00 108.37 ? 284 THR D C   1 
ATOM   16258 O O   . THR D 1 284 ? 181.559 119.440 102.423 1.00 104.00 ? 284 THR D O   1 
ATOM   16259 C CB  . THR D 1 284 ? 182.916 119.367 99.795  1.00 111.89 ? 284 THR D CB  1 
ATOM   16260 O OG1 . THR D 1 284 ? 183.344 120.696 99.599  1.00 111.16 ? 284 THR D OG1 1 
ATOM   16261 C CG2 . THR D 1 284 ? 183.330 118.566 98.565  1.00 106.16 ? 284 THR D CG2 1 
ATOM   16262 N N   . VAL D 1 285 ? 180.329 121.045 101.470 1.00 104.31 ? 285 VAL D N   1 
ATOM   16263 C CA  . VAL D 1 285 ? 180.131 121.833 102.695 1.00 103.96 ? 285 VAL D CA  1 
ATOM   16264 C C   . VAL D 1 285 ? 178.760 121.563 103.308 1.00 102.74 ? 285 VAL D C   1 
ATOM   16265 O O   . VAL D 1 285 ? 177.721 121.710 102.666 1.00 101.06 ? 285 VAL D O   1 
ATOM   16266 C CB  . VAL D 1 285 ? 180.312 123.343 102.449 1.00 103.27 ? 285 VAL D CB  1 
ATOM   16267 C CG1 . VAL D 1 285 ? 180.288 124.111 103.774 1.00 102.64 ? 285 VAL D CG1 1 
ATOM   16268 C CG2 . VAL D 1 285 ? 181.635 123.657 101.747 1.00 101.78 ? 285 VAL D CG2 1 
ATOM   16269 N N   . GLN D 1 286 ? 178.752 121.206 104.589 1.00 101.29 ? 286 GLN D N   1 
ATOM   16270 C CA  . GLN D 1 286 ? 177.544 121.023 105.389 1.00 98.47  ? 286 GLN D CA  1 
ATOM   16271 C C   . GLN D 1 286 ? 177.101 122.375 105.974 1.00 100.27 ? 286 GLN D C   1 
ATOM   16272 O O   . GLN D 1 286 ? 177.486 122.724 107.088 1.00 103.37 ? 286 GLN D O   1 
ATOM   16273 C CB  . GLN D 1 286 ? 177.837 119.978 106.480 1.00 99.06  ? 286 GLN D CB  1 
ATOM   16274 C CG  . GLN D 1 286 ? 178.219 118.583 105.953 1.00 100.75 ? 286 GLN D CG  1 
ATOM   16275 C CD  . GLN D 1 286 ? 177.021 117.775 105.478 1.00 104.13 ? 286 GLN D CD  1 
ATOM   16276 O OE1 . GLN D 1 286 ? 176.774 117.604 104.293 1.00 99.57  ? 286 GLN D OE1 1 
ATOM   16277 N NE2 . GLN D 1 286 ? 176.228 117.244 106.377 1.00 105.48 ? 286 GLN D NE2 1 
ATOM   16278 N N   . LEU D 1 287 ? 176.307 123.152 105.229 1.00 90.56  ? 287 LEU D N   1 
ATOM   16279 C CA  . LEU D 1 287 ? 175.942 124.534 105.591 1.00 82.75  ? 287 LEU D CA  1 
ATOM   16280 C C   . LEU D 1 287 ? 175.201 124.654 106.927 1.00 85.31  ? 287 LEU D C   1 
ATOM   16281 O O   . LEU D 1 287 ? 175.317 125.660 107.618 1.00 90.62  ? 287 LEU D O   1 
ATOM   16282 C CB  . LEU D 1 287 ? 175.081 125.169 104.483 1.00 82.54  ? 287 LEU D CB  1 
ATOM   16283 C CG  . LEU D 1 287 ? 175.746 125.361 103.115 1.00 86.95  ? 287 LEU D CG  1 
ATOM   16284 C CD1 . LEU D 1 287 ? 174.748 126.026 102.180 1.00 85.35  ? 287 LEU D CD1 1 
ATOM   16285 C CD2 . LEU D 1 287 ? 176.980 126.247 103.178 1.00 89.02  ? 287 LEU D CD2 1 
ATOM   16286 N N   . GLU D 1 288 ? 174.474 123.606 107.296 1.00 85.61  ? 288 GLU D N   1 
ATOM   16287 C CA  . GLU D 1 288 ? 173.778 123.486 108.570 1.00 84.13  ? 288 GLU D CA  1 
ATOM   16288 C C   . GLU D 1 288 ? 174.646 122.932 109.703 1.00 85.48  ? 288 GLU D C   1 
ATOM   16289 O O   . GLU D 1 288 ? 174.162 122.780 110.815 1.00 93.26  ? 288 GLU D O   1 
ATOM   16290 C CB  . GLU D 1 288 ? 172.549 122.605 108.390 1.00 85.80  ? 288 GLU D CB  1 
ATOM   16291 C CG  . GLU D 1 288 ? 171.577 123.185 107.374 1.00 85.92  ? 288 GLU D CG  1 
ATOM   16292 C CD  . GLU D 1 288 ? 170.285 122.382 107.389 1.00 90.38  ? 288 GLU D CD  1 
ATOM   16293 O OE1 . GLU D 1 288 ? 170.349 121.141 107.283 1.00 97.16  ? 288 GLU D OE1 1 
ATOM   16294 O OE2 . GLU D 1 288 ? 169.201 122.979 107.537 1.00 81.12  ? 288 GLU D OE2 1 
ATOM   16295 N N   . GLU D 1 289 ? 175.920 122.633 109.456 1.00 86.88  ? 289 GLU D N   1 
ATOM   16296 C CA  . GLU D 1 289 ? 176.910 122.329 110.492 1.00 87.36  ? 289 GLU D CA  1 
ATOM   16297 C C   . GLU D 1 289 ? 177.836 123.523 110.771 1.00 92.68  ? 289 GLU D C   1 
ATOM   16298 O O   . GLU D 1 289 ? 178.683 123.457 111.662 1.00 95.31  ? 289 GLU D O   1 
ATOM   16299 C CB  . GLU D 1 289 ? 177.692 121.061 110.128 1.00 91.23  ? 289 GLU D CB  1 
ATOM   16300 C CG  . GLU D 1 289 ? 176.773 119.831 110.043 1.00 95.29  ? 289 GLU D CG  1 
ATOM   16301 C CD  . GLU D 1 289 ? 177.523 118.535 109.696 1.00 96.28  ? 289 GLU D CD  1 
ATOM   16302 O OE1 . GLU D 1 289 ? 178.699 118.369 110.094 1.00 96.65  ? 289 GLU D OE1 1 
ATOM   16303 O OE2 . GLU D 1 289 ? 176.919 117.662 109.035 1.00 93.96  ? 289 GLU D OE2 1 
ATOM   16304 N N   . ILE D 1 290 ? 177.672 124.637 110.051 1.00 88.19  ? 290 ILE D N   1 
ATOM   16305 C CA  . ILE D 1 290 ? 178.373 125.897 110.312 1.00 80.59  ? 290 ILE D CA  1 
ATOM   16306 C C   . ILE D 1 290 ? 177.808 126.512 111.592 1.00 82.23  ? 290 ILE D C   1 
ATOM   16307 O O   . ILE D 1 290 ? 176.599 126.670 111.729 1.00 83.87  ? 290 ILE D O   1 
ATOM   16308 C CB  . ILE D 1 290 ? 178.278 126.860 109.108 1.00 80.69  ? 290 ILE D CB  1 
ATOM   16309 C CG1 . ILE D 1 290 ? 178.888 126.226 107.842 1.00 82.31  ? 290 ILE D CG1 1 
ATOM   16310 C CG2 . ILE D 1 290 ? 178.999 128.175 109.444 1.00 87.94  ? 290 ILE D CG2 1 
ATOM   16311 C CD1 . ILE D 1 290 ? 178.759 127.065 106.571 1.00 85.11  ? 290 ILE D CD1 1 
ATOM   16312 N N   . SER D 1 291 ? 178.679 126.866 112.532 1.00 81.42  ? 291 SER D N   1 
ATOM   16313 C CA  . SER D 1 291 ? 178.317 127.412 113.845 1.00 76.58  ? 291 SER D CA  1 
ATOM   16314 C C   . SER D 1 291 ? 178.584 128.912 113.924 1.00 83.41  ? 291 SER D C   1 
ATOM   16315 O O   . SER D 1 291 ? 179.660 129.370 113.541 1.00 81.95  ? 291 SER D O   1 
ATOM   16316 C CB  . SER D 1 291 ? 179.111 126.706 114.942 1.00 77.14  ? 291 SER D CB  1 
ATOM   16317 O OG  . SER D 1 291 ? 178.800 125.329 114.971 1.00 82.42  ? 291 SER D OG  1 
ATOM   16318 N N   . ASN D 1 292 ? 177.636 129.693 114.438 1.00 75.85  ? 292 ASN D N   1 
ATOM   16319 C CA  . ASN D 1 292 ? 177.869 131.107 114.735 1.00 70.44  ? 292 ASN D CA  1 
ATOM   16320 C C   . ASN D 1 292 ? 178.771 131.286 115.980 1.00 73.49  ? 292 ASN D C   1 
ATOM   16321 O O   . ASN D 1 292 ? 179.240 130.312 116.566 1.00 78.73  ? 292 ASN D O   1 
ATOM   16322 C CB  . ASN D 1 292 ? 176.510 131.824 114.795 1.00 70.97  ? 292 ASN D CB  1 
ATOM   16323 C CG  . ASN D 1 292 ? 175.673 131.551 116.019 1.00 67.21  ? 292 ASN D CG  1 
ATOM   16324 O OD1 . ASN D 1 292 ? 176.083 130.903 116.964 1.00 77.27  ? 292 ASN D OD1 1 
ATOM   16325 N ND2 . ASN D 1 292 ? 174.481 132.075 116.056 1.00 67.54  ? 292 ASN D ND2 1 
ATOM   16326 N N   . HIS D 1 293 ? 179.033 132.518 116.426 1.00 86.51  ? 293 HIS D N   1 
ATOM   16327 C CA  . HIS D 1 293 ? 179.914 132.765 117.578 1.00 86.22  ? 293 HIS D CA  1 
ATOM   16328 C C   . HIS D 1 293 ? 179.352 132.280 118.923 1.00 87.87  ? 293 HIS D C   1 
ATOM   16329 O O   . HIS D 1 293 ? 180.109 132.155 119.882 1.00 92.93  ? 293 HIS D O   1 
ATOM   16330 C CB  . HIS D 1 293 ? 180.267 134.253 117.650 1.00 81.07  ? 293 HIS D CB  1 
ATOM   16331 C CG  . HIS D 1 293 ? 181.062 134.795 116.488 1.00 85.83  ? 293 HIS D CG  1 
ATOM   16332 N ND1 . HIS D 1 293 ? 181.343 136.143 116.298 1.00 92.29  ? 293 HIS D ND1 1 
ATOM   16333 C CD2 . HIS D 1 293 ? 181.679 134.082 115.500 1.00 85.13  ? 293 HIS D CD2 1 
ATOM   16334 C CE1 . HIS D 1 293 ? 182.099 136.220 115.191 1.00 88.68  ? 293 HIS D CE1 1 
ATOM   16335 N NE2 . HIS D 1 293 ? 182.318 134.996 114.696 1.00 85.15  ? 293 HIS D NE2 1 
ATOM   16336 N N   . GLN D 1 294 ? 178.059 131.958 119.011 1.00 81.88  ? 294 GLN D N   1 
ATOM   16337 C CA  . GLN D 1 294 ? 177.460 131.268 120.161 1.00 82.12  ? 294 GLN D CA  1 
ATOM   16338 C C   . GLN D 1 294 ? 177.557 129.733 120.064 1.00 87.80  ? 294 GLN D C   1 
ATOM   16339 O O   . GLN D 1 294 ? 177.037 129.026 120.925 1.00 85.59  ? 294 GLN D O   1 
ATOM   16340 C CB  . GLN D 1 294 ? 175.999 131.701 120.347 1.00 84.26  ? 294 GLN D CB  1 
ATOM   16341 C CG  . GLN D 1 294 ? 175.840 133.213 120.523 1.00 88.36  ? 294 GLN D CG  1 
ATOM   16342 C CD  . GLN D 1 294 ? 174.467 133.631 121.046 1.00 92.26  ? 294 GLN D CD  1 
ATOM   16343 O OE1 . GLN D 1 294 ? 173.689 132.850 121.581 1.00 90.39  ? 294 GLN D OE1 1 
ATOM   16344 N NE2 . GLN D 1 294 ? 174.117 134.889 120.934 1.00 87.52  ? 294 GLN D NE2 1 
ATOM   16345 N N   . GLY D 1 295 ? 178.190 129.194 119.021 1.00 84.54  ? 295 GLY D N   1 
ATOM   16346 C CA  . GLY D 1 295 ? 178.301 127.757 118.769 1.00 79.75  ? 295 GLY D CA  1 
ATOM   16347 C C   . GLY D 1 295 ? 177.037 127.114 118.195 1.00 83.12  ? 295 GLY D C   1 
ATOM   16348 O O   . GLY D 1 295 ? 176.922 125.893 118.191 1.00 90.54  ? 295 GLY D O   1 
ATOM   16349 N N   . LEU D 1 296 ? 176.072 127.905 117.726 1.00 73.54  ? 296 LEU D N   1 
ATOM   16350 C CA  . LEU D 1 296 ? 174.779 127.416 117.256 1.00 66.85  ? 296 LEU D CA  1 
ATOM   16351 C C   . LEU D 1 296 ? 174.799 127.216 115.741 1.00 71.72  ? 296 LEU D C   1 
ATOM   16352 O O   . LEU D 1 296 ? 175.169 128.106 114.982 1.00 75.19  ? 296 LEU D O   1 
ATOM   16353 C CB  . LEU D 1 296 ? 173.658 128.392 117.651 1.00 66.27  ? 296 LEU D CB  1 
ATOM   16354 C CG  . LEU D 1 296 ? 173.558 128.690 119.151 1.00 67.99  ? 296 LEU D CG  1 
ATOM   16355 C CD1 . LEU D 1 296 ? 172.601 129.842 119.388 1.00 71.42  ? 296 LEU D CD1 1 
ATOM   16356 C CD2 . LEU D 1 296 ? 173.039 127.510 119.952 1.00 71.30  ? 296 LEU D CD2 1 
ATOM   16357 N N   . THR D 1 297 ? 174.353 126.052 115.290 1.00 73.82  ? 297 THR D N   1 
ATOM   16358 C CA  . THR D 1 297 ? 173.929 125.809 113.911 1.00 64.06  ? 297 THR D CA  1 
ATOM   16359 C C   . THR D 1 297 ? 172.536 126.407 113.670 1.00 63.74  ? 297 THR D C   1 
ATOM   16360 O O   . THR D 1 297 ? 171.853 126.742 114.637 1.00 66.69  ? 297 THR D O   1 
ATOM   16361 C CB  . THR D 1 297 ? 173.919 124.305 113.644 1.00 60.71  ? 297 THR D CB  1 
ATOM   16362 O OG1 . THR D 1 297 ? 173.037 123.643 114.512 1.00 69.55  ? 297 THR D OG1 1 
ATOM   16363 C CG2 . THR D 1 297 ? 175.289 123.669 113.827 1.00 58.48  ? 297 THR D CG2 1 
ATOM   16364 N N   . PRO D 1 298 ? 172.044 126.530 112.424 1.00 52.09  ? 298 PRO D N   1 
ATOM   16365 C CA  . PRO D 1 298 ? 170.698 127.028 112.157 1.00 52.09  ? 298 PRO D CA  1 
ATOM   16366 C C   . PRO D 1 298 ? 169.571 126.290 112.907 1.00 50.98  ? 298 PRO D C   1 
ATOM   16367 O O   . PRO D 1 298 ? 168.682 126.943 113.439 1.00 56.21  ? 298 PRO D O   1 
ATOM   16368 C CB  . PRO D 1 298 ? 170.534 126.924 110.644 1.00 61.02  ? 298 PRO D CB  1 
ATOM   16369 C CG  . PRO D 1 298 ? 171.954 127.047 110.118 1.00 54.05  ? 298 PRO D CG  1 
ATOM   16370 C CD  . PRO D 1 298 ? 172.767 126.327 111.181 1.00 57.41  ? 298 PRO D CD  1 
ATOM   16371 N N   . LEU D 1 299 ? 169.619 124.959 113.036 1.00 54.58  ? 299 LEU D N   1 
ATOM   16372 C CA  . LEU D 1 299 ? 168.632 124.183 113.803 1.00 57.38  ? 299 LEU D CA  1 
ATOM   16373 C C   . LEU D 1 299 ? 168.677 124.501 115.303 1.00 67.24  ? 299 LEU D C   1 
ATOM   16374 O O   . LEU D 1 299 ? 167.640 124.695 115.931 1.00 69.74  ? 299 LEU D O   1 
ATOM   16375 C CB  . LEU D 1 299 ? 168.847 122.678 113.552 1.00 56.18  ? 299 LEU D CB  1 
ATOM   16376 C CG  . LEU D 1 299 ? 167.890 121.753 114.338 1.00 49.48  ? 299 LEU D CG  1 
ATOM   16377 C CD1 . LEU D 1 299 ? 166.438 121.927 113.933 1.00 57.77  ? 299 LEU D CD1 1 
ATOM   16378 C CD2 . LEU D 1 299 ? 168.257 120.299 114.122 1.00 61.32  ? 299 LEU D CD2 1 
ATOM   16379 N N   . LYS D 1 300 ? 169.876 124.587 115.886 1.00 70.45  ? 300 LYS D N   1 
ATOM   16380 C CA  . LYS D 1 300 ? 170.068 124.945 117.298 1.00 55.05  ? 300 LYS D CA  1 
ATOM   16381 C C   . LYS D 1 300 ? 169.650 126.386 117.584 1.00 60.99  ? 300 LYS D C   1 
ATOM   16382 O O   . LYS D 1 300 ? 169.064 126.655 118.622 1.00 74.73  ? 300 LYS D O   1 
ATOM   16383 C CB  . LYS D 1 300 ? 171.531 124.728 117.691 1.00 62.06  ? 300 LYS D CB  1 
ATOM   16384 C CG  . LYS D 1 300 ? 171.923 123.252 117.764 1.00 55.44  ? 300 LYS D CG  1 
ATOM   16385 C CD  . LYS D 1 300 ? 173.355 123.120 118.282 1.00 57.92  ? 300 LYS D CD  1 
ATOM   16386 C CE  . LYS D 1 300 ? 173.813 121.669 118.211 1.00 64.44  ? 300 LYS D CE  1 
ATOM   16387 N NZ  . LYS D 1 300 ? 175.142 121.484 118.836 1.00 66.28  ? 300 LYS D NZ  1 
ATOM   16388 N N   . LEU D 1 301 ? 169.897 127.310 116.662 1.00 60.57  ? 301 LEU D N   1 
ATOM   16389 C CA  . LEU D 1 301 ? 169.432 128.688 116.757 1.00 65.04  ? 301 LEU D CA  1 
ATOM   16390 C C   . LEU D 1 301 ? 167.905 128.789 116.683 1.00 67.85  ? 301 LEU D C   1 
ATOM   16391 O O   . LEU D 1 301 ? 167.316 129.557 117.432 1.00 72.17  ? 301 LEU D O   1 
ATOM   16392 C CB  . LEU D 1 301 ? 170.128 129.512 115.665 1.00 60.38  ? 301 LEU D CB  1 
ATOM   16393 C CG  . LEU D 1 301 ? 169.781 131.003 115.680 1.00 50.36  ? 301 LEU D CG  1 
ATOM   16394 C CD1 . LEU D 1 301 ? 170.287 131.704 116.931 1.00 57.87  ? 301 LEU D CD1 1 
ATOM   16395 C CD2 . LEU D 1 301 ? 170.427 131.676 114.486 1.00 56.24  ? 301 LEU D CD2 1 
ATOM   16396 N N   . ALA D 1 302 ? 167.233 127.987 115.860 1.00 64.16  ? 302 ALA D N   1 
ATOM   16397 C CA  . ALA D 1 302 ? 165.775 127.973 115.798 1.00 46.81  ? 302 ALA D CA  1 
ATOM   16398 C C   . ALA D 1 302 ? 165.130 127.510 117.117 1.00 62.83  ? 302 ALA D C   1 
ATOM   16399 O O   . ALA D 1 302 ? 164.080 128.022 117.484 1.00 72.14  ? 302 ALA D O   1 
ATOM   16400 C CB  . ALA D 1 302 ? 165.354 127.117 114.604 1.00 44.06  ? 302 ALA D CB  1 
ATOM   16401 N N   . ALA D 1 303 ? 165.780 126.610 117.861 1.00 69.16  ? 303 ALA D N   1 
ATOM   16402 C CA  . ALA D 1 303 ? 165.403 126.176 119.202 1.00 57.75  ? 303 ALA D CA  1 
ATOM   16403 C C   . ALA D 1 303 ? 165.647 127.251 120.273 1.00 68.14  ? 303 ALA D C   1 
ATOM   16404 O O   . ALA D 1 303 ? 164.753 127.536 121.065 1.00 73.68  ? 303 ALA D O   1 
ATOM   16405 C CB  . ALA D 1 303 ? 166.178 124.899 119.514 1.00 58.19  ? 303 ALA D CB  1 
ATOM   16406 N N   . LYS D 1 304 ? 166.814 127.905 120.270 1.00 68.36  ? 304 LYS D N   1 
ATOM   16407 C CA  . LYS D 1 304 ? 167.143 128.952 121.243 1.00 58.28  ? 304 LYS D CA  1 
ATOM   16408 C C   . LYS D 1 304 ? 166.264 130.191 121.087 1.00 67.84  ? 304 LYS D C   1 
ATOM   16409 O O   . LYS D 1 304 ? 165.789 130.743 122.073 1.00 72.79  ? 304 LYS D O   1 
ATOM   16410 C CB  . LYS D 1 304 ? 168.630 129.296 121.140 1.00 60.71  ? 304 LYS D CB  1 
ATOM   16411 C CG  . LYS D 1 304 ? 169.059 130.122 122.352 1.00 76.65  ? 304 LYS D CG  1 
ATOM   16412 C CD  . LYS D 1 304 ? 170.557 130.391 122.339 1.00 77.53  ? 304 LYS D CD  1 
ATOM   16413 C CE  . LYS D 1 304 ? 170.971 131.164 123.590 1.00 75.00  ? 304 LYS D CE  1 
ATOM   16414 N NZ  . LYS D 1 304 ? 172.437 131.377 123.626 1.00 79.10  ? 304 LYS D NZ  1 
ATOM   16415 N N   . GLU D 1 305 ? 165.994 130.597 119.854 1.00 76.41  ? 305 GLU D N   1 
ATOM   16416 C CA  . GLU D 1 305 ? 165.096 131.707 119.521 1.00 71.04  ? 305 GLU D CA  1 
ATOM   16417 C C   . GLU D 1 305 ? 163.606 131.314 119.533 1.00 72.89  ? 305 GLU D C   1 
ATOM   16418 O O   . GLU D 1 305 ? 162.744 132.177 119.407 1.00 74.73  ? 305 GLU D O   1 
ATOM   16419 C CB  . GLU D 1 305 ? 165.516 132.301 118.170 1.00 67.51  ? 305 GLU D CB  1 
ATOM   16420 C CG  . GLU D 1 305 ? 166.938 132.878 118.168 1.00 72.79  ? 305 GLU D CG  1 
ATOM   16421 C CD  . GLU D 1 305 ? 167.118 134.047 119.149 1.00 81.16  ? 305 GLU D CD  1 
ATOM   16422 O OE1 . GLU D 1 305 ? 166.262 134.960 119.168 1.00 83.44  ? 305 GLU D OE1 1 
ATOM   16423 O OE2 . GLU D 1 305 ? 168.123 134.068 119.895 1.00 80.80  ? 305 GLU D OE2 1 
ATOM   16424 N N   . GLY D 1 306 ? 163.276 130.031 119.703 1.00 64.84  ? 306 GLY D N   1 
ATOM   16425 C CA  . GLY D 1 306 ? 161.903 129.549 119.855 1.00 60.32  ? 306 GLY D CA  1 
ATOM   16426 C C   . GLY D 1 306 ? 161.047 129.625 118.600 1.00 61.33  ? 306 GLY D C   1 
ATOM   16427 O O   . GLY D 1 306 ? 159.838 129.807 118.696 1.00 70.80  ? 306 GLY D O   1 
ATOM   16428 N N   . LYS D 1 307 ? 161.645 129.545 117.414 1.00 67.75  ? 307 LYS D N   1 
ATOM   16429 C CA  . LYS D 1 307 ? 160.965 129.724 116.126 1.00 71.25  ? 307 LYS D CA  1 
ATOM   16430 C C   . LYS D 1 307 ? 160.314 128.422 115.665 1.00 76.03  ? 307 LYS D C   1 
ATOM   16431 O O   . LYS D 1 307 ? 160.870 127.742 114.813 1.00 74.27  ? 307 LYS D O   1 
ATOM   16432 C CB  . LYS D 1 307 ? 161.958 130.274 115.087 1.00 61.65  ? 307 LYS D CB  1 
ATOM   16433 C CG  . LYS D 1 307 ? 162.710 131.547 115.478 1.00 69.65  ? 307 LYS D CG  1 
ATOM   16434 C CD  . LYS D 1 307 ? 161.766 132.691 115.856 1.00 70.03  ? 307 LYS D CD  1 
ATOM   16435 C CE  . LYS D 1 307 ? 162.521 133.996 116.095 1.00 67.05  ? 307 LYS D CE  1 
ATOM   16436 N NZ  . LYS D 1 307 ? 163.064 134.544 114.836 1.00 70.21  ? 307 LYS D NZ  1 
ATOM   16437 N N   . ILE D 1 308 ? 159.161 128.036 116.210 1.00 79.20  ? 308 ILE D N   1 
ATOM   16438 C CA  . ILE D 1 308 ? 158.612 126.676 116.029 1.00 69.61  ? 308 ILE D CA  1 
ATOM   16439 C C   . ILE D 1 308 ? 158.444 126.290 114.557 1.00 69.38  ? 308 ILE D C   1 
ATOM   16440 O O   . ILE D 1 308 ? 158.732 125.161 114.197 1.00 78.62  ? 308 ILE D O   1 
ATOM   16441 C CB  . ILE D 1 308 ? 157.263 126.470 116.753 1.00 73.81  ? 308 ILE D CB  1 
ATOM   16442 C CG1 . ILE D 1 308 ? 157.284 126.889 118.227 1.00 75.52  ? 308 ILE D CG1 1 
ATOM   16443 C CG2 . ILE D 1 308 ? 156.839 124.990 116.688 1.00 73.72  ? 308 ILE D CG2 1 
ATOM   16444 C CD1 . ILE D 1 308 ? 155.870 127.196 118.725 1.00 82.24  ? 308 ILE D CD1 1 
ATOM   16445 N N   . GLU D 1 309 ? 157.995 127.193 113.687 1.00 77.67  ? 309 GLU D N   1 
ATOM   16446 C CA  . GLU D 1 309 ? 157.656 126.831 112.306 1.00 77.85  ? 309 GLU D CA  1 
ATOM   16447 C C   . GLU D 1 309 ? 158.876 126.453 111.462 1.00 76.16  ? 309 GLU D C   1 
ATOM   16448 O O   . GLU D 1 309 ? 158.886 125.404 110.823 1.00 76.94  ? 309 GLU D O   1 
ATOM   16449 C CB  . GLU D 1 309 ? 156.893 127.976 111.627 1.00 82.19  ? 309 GLU D CB  1 
ATOM   16450 C CG  . GLU D 1 309 ? 155.611 128.424 112.344 1.00 85.28  ? 309 GLU D CG  1 
ATOM   16451 C CD  . GLU D 1 309 ? 154.597 127.296 112.580 1.00 87.52  ? 309 GLU D CD  1 
ATOM   16452 O OE1 . GLU D 1 309 ? 154.643 126.263 111.873 1.00 85.71  ? 309 GLU D OE1 1 
ATOM   16453 O OE2 . GLU D 1 309 ? 153.740 127.427 113.481 1.00 85.86  ? 309 GLU D OE2 1 
ATOM   16454 N N   . ILE D 1 310 ? 159.932 127.268 111.477 1.00 68.10  ? 310 ILE D N   1 
ATOM   16455 C CA  . ILE D 1 310 ? 161.196 126.932 110.816 1.00 64.45  ? 310 ILE D CA  1 
ATOM   16456 C C   . ILE D 1 310 ? 161.936 125.811 111.551 1.00 70.81  ? 310 ILE D C   1 
ATOM   16457 O O   . ILE D 1 310 ? 162.552 124.976 110.900 1.00 72.43  ? 310 ILE D O   1 
ATOM   16458 C CB  . ILE D 1 310 ? 162.052 128.192 110.562 1.00 65.48  ? 310 ILE D CB  1 
ATOM   16459 C CG1 . ILE D 1 310 ? 163.331 127.935 109.737 1.00 72.32  ? 310 ILE D CG1 1 
ATOM   16460 C CG2 . ILE D 1 310 ? 162.469 128.882 111.864 1.00 67.34  ? 310 ILE D CG2 1 
ATOM   16461 C CD1 . ILE D 1 310 ? 163.079 127.379 108.332 1.00 75.07  ? 310 ILE D CD1 1 
ATOM   16462 N N   . PHE D 1 311 ? 161.834 125.711 112.881 1.00 72.85  ? 311 PHE D N   1 
ATOM   16463 C CA  . PHE D 1 311 ? 162.391 124.601 113.658 1.00 60.87  ? 311 PHE D CA  1 
ATOM   16464 C C   . PHE D 1 311 ? 161.785 123.257 113.244 1.00 63.63  ? 311 PHE D C   1 
ATOM   16465 O O   . PHE D 1 311 ? 162.508 122.364 112.823 1.00 66.20  ? 311 PHE D O   1 
ATOM   16466 C CB  . PHE D 1 311 ? 162.176 124.867 115.151 1.00 54.92  ? 311 PHE D CB  1 
ATOM   16467 C CG  . PHE D 1 311 ? 162.651 123.747 116.045 1.00 62.62  ? 311 PHE D CG  1 
ATOM   16468 C CD1 . PHE D 1 311 ? 164.022 123.462 116.130 1.00 62.92  ? 311 PHE D CD1 1 
ATOM   16469 C CD2 . PHE D 1 311 ? 161.732 122.976 116.777 1.00 63.78  ? 311 PHE D CD2 1 
ATOM   16470 C CE1 . PHE D 1 311 ? 164.474 122.403 116.919 1.00 58.24  ? 311 PHE D CE1 1 
ATOM   16471 C CE2 . PHE D 1 311 ? 162.183 121.912 117.566 1.00 63.66  ? 311 PHE D CE2 1 
ATOM   16472 C CZ  . PHE D 1 311 ? 163.551 121.624 117.627 1.00 65.50  ? 311 PHE D CZ  1 
ATOM   16473 N N   . ARG D 1 312 ? 160.452 123.139 113.275 1.00 66.67  ? 312 ARG D N   1 
ATOM   16474 C CA  . ARG D 1 312 ? 159.686 121.982 112.805 1.00 58.49  ? 312 ARG D CA  1 
ATOM   16475 C C   . ARG D 1 312 ? 160.040 121.619 111.378 1.00 67.40  ? 312 ARG D C   1 
ATOM   16476 O O   . ARG D 1 312 ? 160.260 120.448 111.097 1.00 75.74  ? 312 ARG D O   1 
ATOM   16477 C CB  . ARG D 1 312 ? 158.191 122.302 112.929 1.00 63.19  ? 312 ARG D CB  1 
ATOM   16478 C CG  . ARG D 1 312 ? 157.291 121.247 112.275 1.00 65.41  ? 312 ARG D CG  1 
ATOM   16479 C CD  . ARG D 1 312 ? 155.858 121.278 112.798 1.00 73.05  ? 312 ARG D CD  1 
ATOM   16480 N NE  . ARG D 1 312 ? 155.232 122.611 112.753 1.00 78.77  ? 312 ARG D NE  1 
ATOM   16481 C CZ  . ARG D 1 312 ? 154.155 122.966 113.429 1.00 79.62  ? 312 ARG D CZ  1 
ATOM   16482 N NH1 . ARG D 1 312 ? 153.666 124.160 113.330 1.00 74.59  ? 312 ARG D NH1 1 
ATOM   16483 N NH2 . ARG D 1 312 ? 153.529 122.140 114.212 1.00 77.07  ? 312 ARG D NH2 1 
ATOM   16484 N N   . HIS D 1 313 ? 160.118 122.596 110.480 1.00 64.93  ? 313 HIS D N   1 
ATOM   16485 C CA  . HIS D 1 313 ? 160.473 122.334 109.095 1.00 53.76  ? 313 HIS D CA  1 
ATOM   16486 C C   . HIS D 1 313 ? 161.863 121.729 108.962 1.00 62.15  ? 313 HIS D C   1 
ATOM   16487 O O   . HIS D 1 313 ? 161.978 120.666 108.371 1.00 75.48  ? 313 HIS D O   1 
ATOM   16488 C CB  . HIS D 1 313 ? 160.348 123.598 108.259 1.00 67.91  ? 313 HIS D CB  1 
ATOM   16489 C CG  . HIS D 1 313 ? 160.777 123.332 106.843 1.00 74.71  ? 313 HIS D CG  1 
ATOM   16490 N ND1 . HIS D 1 313 ? 160.060 122.575 105.916 1.00 67.33  ? 313 HIS D ND1 1 
ATOM   16491 C CD2 . HIS D 1 313 ? 161.986 123.664 106.313 1.00 68.19  ? 313 HIS D CD2 1 
ATOM   16492 C CE1 . HIS D 1 313 ? 160.855 122.480 104.840 1.00 65.28  ? 313 HIS D CE1 1 
ATOM   16493 N NE2 . HIS D 1 313 ? 162.013 123.115 105.058 1.00 60.32  ? 313 HIS D NE2 1 
ATOM   16494 N N   . ILE D 1 314 ? 162.913 122.332 109.527 1.00 62.98  ? 314 ILE D N   1 
ATOM   16495 C CA  . ILE D 1 314 ? 164.276 121.789 109.441 1.00 63.52  ? 314 ILE D CA  1 
ATOM   16496 C C   . ILE D 1 314 ? 164.317 120.374 110.023 1.00 57.93  ? 314 ILE D C   1 
ATOM   16497 O O   . ILE D 1 314 ? 164.809 119.447 109.390 1.00 68.08  ? 314 ILE D O   1 
ATOM   16498 C CB  . ILE D 1 314 ? 165.293 122.710 110.154 1.00 68.48  ? 314 ILE D CB  1 
ATOM   16499 C CG1 . ILE D 1 314 ? 165.397 124.099 109.492 1.00 61.78  ? 314 ILE D CG1 1 
ATOM   16500 C CG2 . ILE D 1 314 ? 166.690 122.064 110.163 1.00 63.16  ? 314 ILE D CG2 1 
ATOM   16501 C CD1 . ILE D 1 314 ? 166.037 125.151 110.402 1.00 58.04  ? 314 ILE D CD1 1 
ATOM   16502 N N   . LEU D 1 315 ? 163.757 120.200 111.217 1.00 54.75  ? 315 LEU D N   1 
ATOM   16503 C CA  . LEU D 1 315 ? 163.776 118.975 112.009 1.00 56.71  ? 315 LEU D CA  1 
ATOM   16504 C C   . LEU D 1 315 ? 163.138 117.771 111.292 1.00 60.42  ? 315 LEU D C   1 
ATOM   16505 O O   . LEU D 1 315 ? 163.632 116.653 111.405 1.00 58.37  ? 315 LEU D O   1 
ATOM   16506 C CB  . LEU D 1 315 ? 163.039 119.342 113.304 1.00 55.72  ? 315 LEU D CB  1 
ATOM   16507 C CG  . LEU D 1 315 ? 162.970 118.260 114.370 1.00 55.74  ? 315 LEU D CG  1 
ATOM   16508 C CD1 . LEU D 1 315 ? 164.307 118.163 115.095 1.00 60.48  ? 315 LEU D CD1 1 
ATOM   16509 C CD2 . LEU D 1 315 ? 161.866 118.621 115.353 1.00 53.29  ? 315 LEU D CD2 1 
ATOM   16510 N N   . GLN D 1 316 ? 162.061 117.994 110.545 1.00 66.47  ? 316 GLN D N   1 
ATOM   16511 C CA  . GLN D 1 316 ? 161.262 116.966 109.876 1.00 55.56  ? 316 GLN D CA  1 
ATOM   16512 C C   . GLN D 1 316 ? 161.450 116.926 108.350 1.00 56.46  ? 316 GLN D C   1 
ATOM   16513 O O   . GLN D 1 316 ? 160.690 116.262 107.654 1.00 64.01  ? 316 GLN D O   1 
ATOM   16514 C CB  . GLN D 1 316 ? 159.784 117.175 110.234 1.00 54.70  ? 316 GLN D CB  1 
ATOM   16515 C CG  . GLN D 1 316 ? 159.521 117.189 111.744 1.00 64.50  ? 316 GLN D CG  1 
ATOM   16516 C CD  . GLN D 1 316 ? 158.047 117.337 112.090 1.00 64.88  ? 316 GLN D CD  1 
ATOM   16517 O OE1 . GLN D 1 316 ? 157.206 117.688 111.278 1.00 68.29  ? 316 GLN D OE1 1 
ATOM   16518 N NE2 . GLN D 1 316 ? 157.676 117.067 113.316 1.00 66.15  ? 316 GLN D NE2 1 
ATOM   16519 N N   . ARG D 1 317 ? 162.429 117.647 107.805 1.00 62.04  ? 317 ARG D N   1 
ATOM   16520 C CA  . ARG D 1 317 ? 162.597 117.884 106.365 1.00 63.86  ? 317 ARG D CA  1 
ATOM   16521 C C   . ARG D 1 317 ? 162.831 116.608 105.566 1.00 72.51  ? 317 ARG D C   1 
ATOM   16522 O O   . ARG D 1 317 ? 163.728 115.839 105.896 1.00 77.90  ? 317 ARG D O   1 
ATOM   16523 C CB  . ARG D 1 317 ? 163.771 118.846 106.199 1.00 60.09  ? 317 ARG D CB  1 
ATOM   16524 C CG  . ARG D 1 317 ? 163.896 119.410 104.785 1.00 67.35  ? 317 ARG D CG  1 
ATOM   16525 C CD  . ARG D 1 317 ? 164.959 120.506 104.782 1.00 72.03  ? 317 ARG D CD  1 
ATOM   16526 N NE  . ARG D 1 317 ? 166.273 119.961 105.152 1.00 71.96  ? 317 ARG D NE  1 
ATOM   16527 C CZ  . ARG D 1 317 ? 167.163 120.481 105.962 1.00 66.89  ? 317 ARG D CZ  1 
ATOM   16528 N NH1 . ARG D 1 317 ? 168.245 119.826 106.213 1.00 60.17  ? 317 ARG D NH1 1 
ATOM   16529 N NH2 . ARG D 1 317 ? 167.017 121.651 106.489 1.00 70.51  ? 317 ARG D NH2 1 
ATOM   16530 N N   . GLU D 1 318 ? 162.102 116.418 104.473 1.00 76.44  ? 318 GLU D N   1 
ATOM   16531 C CA  . GLU D 1 318 ? 162.226 115.273 103.569 1.00 72.94  ? 318 GLU D CA  1 
ATOM   16532 C C   . GLU D 1 318 ? 162.219 115.730 102.106 1.00 81.31  ? 318 GLU D C   1 
ATOM   16533 O O   . GLU D 1 318 ? 161.374 116.537 101.719 1.00 77.91  ? 318 GLU D O   1 
ATOM   16534 C CB  . GLU D 1 318 ? 161.085 114.291 103.870 1.00 78.10  ? 318 GLU D CB  1 
ATOM   16535 C CG  . GLU D 1 318 ? 161.143 112.989 103.060 1.00 83.41  ? 318 GLU D CG  1 
ATOM   16536 C CD  . GLU D 1 318 ? 160.132 111.951 103.566 1.00 85.16  ? 318 GLU D CD  1 
ATOM   16537 O OE1 . GLU D 1 318 ? 159.030 112.341 104.006 1.00 87.02  ? 318 GLU D OE1 1 
ATOM   16538 O OE2 . GLU D 1 318 ? 160.407 110.729 103.486 1.00 84.73  ? 318 GLU D OE2 1 
ATOM   16539 N N   . PHE D 1 319 ? 163.120 115.193 101.283 1.00 92.69  ? 319 PHE D N   1 
ATOM   16540 C CA  . PHE D 1 319 ? 163.221 115.462 99.846  1.00 84.22  ? 319 PHE D CA  1 
ATOM   16541 C C   . PHE D 1 319 ? 163.376 114.161 99.045  1.00 89.26  ? 319 PHE D C   1 
ATOM   16542 O O   . PHE D 1 319 ? 163.812 113.138 99.571  1.00 89.18  ? 319 PHE D O   1 
ATOM   16543 C CB  . PHE D 1 319 ? 164.419 116.373 99.554  1.00 80.64  ? 319 PHE D CB  1 
ATOM   16544 C CG  . PHE D 1 319 ? 164.396 117.765 100.144 1.00 85.90  ? 319 PHE D CG  1 
ATOM   16545 C CD1 . PHE D 1 319 ? 163.368 118.670 99.823  1.00 90.44  ? 319 PHE D CD1 1 
ATOM   16546 C CD2 . PHE D 1 319 ? 165.458 118.187 100.947 1.00 84.74  ? 319 PHE D CD2 1 
ATOM   16547 C CE1 . PHE D 1 319 ? 163.414 119.989 100.310 1.00 88.60  ? 319 PHE D CE1 1 
ATOM   16548 C CE2 . PHE D 1 319 ? 165.516 119.508 101.416 1.00 84.03  ? 319 PHE D CE2 1 
ATOM   16549 C CZ  . PHE D 1 319 ? 164.493 120.410 101.100 1.00 86.64  ? 319 PHE D CZ  1 
ATOM   16550 N N   . SER D 1 320 ? 163.078 114.219 97.748  1.00 111.39 ? 320 SER D N   1 
ATOM   16551 C CA  . SER D 1 320 ? 163.243 113.122 96.788  1.00 112.20 ? 320 SER D CA  1 
ATOM   16552 C C   . SER D 1 320 ? 164.147 113.535 95.621  1.00 113.00 ? 320 SER D C   1 
ATOM   16553 O O   . SER D 1 320 ? 164.285 114.717 95.302  1.00 110.26 ? 320 SER D O   1 
ATOM   16554 C CB  . SER D 1 320 ? 161.877 112.638 96.294  1.00 108.90 ? 320 SER D CB  1 
ATOM   16555 O OG  . SER D 1 320 ? 161.193 113.671 95.610  1.00 110.02 ? 320 SER D OG  1 
ATOM   16556 N N   . GLY D 1 321 ? 164.809 112.567 94.990  1.00 107.71 ? 321 GLY D N   1 
ATOM   16557 C CA  . GLY D 1 321 ? 165.701 112.833 93.860  1.00 106.63 ? 321 GLY D CA  1 
ATOM   16558 C C   . GLY D 1 321 ? 167.051 113.428 94.289  1.00 108.95 ? 321 GLY D C   1 
ATOM   16559 O O   . GLY D 1 321 ? 167.624 112.946 95.270  1.00 110.26 ? 321 GLY D O   1 
ATOM   16560 N N   . PRO D 1 322 ? 167.596 114.445 93.589  1.00 109.84 ? 322 PRO D N   1 
ATOM   16561 C CA  . PRO D 1 322 ? 168.951 114.960 93.807  1.00 109.59 ? 322 PRO D CA  1 
ATOM   16562 C C   . PRO D 1 322 ? 169.255 115.406 95.243  1.00 107.78 ? 322 PRO D C   1 
ATOM   16563 O O   . PRO D 1 322 ? 170.383 115.272 95.711  1.00 106.29 ? 322 PRO D O   1 
ATOM   16564 C CB  . PRO D 1 322 ? 169.080 116.157 92.858  1.00 109.17 ? 322 PRO D CB  1 
ATOM   16565 C CG  . PRO D 1 322 ? 168.107 115.843 91.732  1.00 106.48 ? 322 PRO D CG  1 
ATOM   16566 C CD  . PRO D 1 322 ? 166.984 115.101 92.443  1.00 107.60 ? 322 PRO D CD  1 
ATOM   16567 N N   . TYR D 1 323 ? 168.228 115.894 95.937  1.00 93.97  ? 323 TYR D N   1 
ATOM   16568 C CA  . TYR D 1 323 ? 168.315 116.535 97.241  1.00 95.23  ? 323 TYR D CA  1 
ATOM   16569 C C   . TYR D 1 323 ? 168.037 115.613 98.432  1.00 93.23  ? 323 TYR D C   1 
ATOM   16570 O O   . TYR D 1 323 ? 167.980 116.092 99.559  1.00 97.11  ? 323 TYR D O   1 
ATOM   16571 C CB  . TYR D 1 323 ? 167.378 117.751 97.216  1.00 100.69 ? 323 TYR D CB  1 
ATOM   16572 C CG  . TYR D 1 323 ? 167.663 118.712 96.077  1.00 96.90  ? 323 TYR D CG  1 
ATOM   16573 C CD1 . TYR D 1 323 ? 168.980 119.146 95.821  1.00 96.31  ? 323 TYR D CD1 1 
ATOM   16574 C CD2 . TYR D 1 323 ? 166.613 119.148 95.250  1.00 94.79  ? 323 TYR D CD2 1 
ATOM   16575 C CE1 . TYR D 1 323 ? 169.254 119.982 94.724  1.00 94.85  ? 323 TYR D CE1 1 
ATOM   16576 C CE2 . TYR D 1 323 ? 166.882 119.992 94.157  1.00 98.54  ? 323 TYR D CE2 1 
ATOM   16577 C CZ  . TYR D 1 323 ? 168.202 120.400 93.887  1.00 98.17  ? 323 TYR D CZ  1 
ATOM   16578 O OH  . TYR D 1 323 ? 168.462 121.200 92.824  1.00 96.58  ? 323 TYR D OH  1 
ATOM   16579 N N   . GLN D 1 324 ? 167.898 114.298 98.246  1.00 92.57  ? 324 GLN D N   1 
ATOM   16580 C CA  . GLN D 1 324 ? 167.613 113.386 99.357  1.00 93.37  ? 324 GLN D CA  1 
ATOM   16581 C C   . GLN D 1 324 ? 168.587 113.514 100.558 1.00 93.55  ? 324 GLN D C   1 
ATOM   16582 O O   . GLN D 1 324 ? 168.086 113.567 101.678 1.00 92.85  ? 324 GLN D O   1 
ATOM   16583 C CB  . GLN D 1 324 ? 167.455 111.948 98.836  1.00 91.33  ? 324 GLN D CB  1 
ATOM   16584 C CG  . GLN D 1 324 ? 167.091 110.958 99.947  1.00 95.55  ? 324 GLN D CG  1 
ATOM   16585 C CD  . GLN D 1 324 ? 166.717 109.577 99.419  1.00 96.39  ? 324 GLN D CD  1 
ATOM   16586 O OE1 . GLN D 1 324 ? 167.222 109.102 98.421  1.00 95.87  ? 324 GLN D OE1 1 
ATOM   16587 N NE2 . GLN D 1 324 ? 165.825 108.872 100.058 1.00 94.68  ? 324 GLN D NE2 1 
ATOM   16588 N N   . PRO D 1 325 ? 169.920 113.655 100.401 1.00 88.38  ? 325 PRO D N   1 
ATOM   16589 C CA  . PRO D 1 325 ? 170.860 113.858 101.506 1.00 88.71  ? 325 PRO D CA  1 
ATOM   16590 C C   . PRO D 1 325 ? 170.646 115.131 102.337 1.00 86.62  ? 325 PRO D C   1 
ATOM   16591 O O   . PRO D 1 325 ? 171.137 115.215 103.456 1.00 89.31  ? 325 PRO D O   1 
ATOM   16592 C CB  . PRO D 1 325 ? 172.250 113.879 100.868 1.00 87.59  ? 325 PRO D CB  1 
ATOM   16593 C CG  . PRO D 1 325 ? 172.071 113.049 99.609  1.00 88.74  ? 325 PRO D CG  1 
ATOM   16594 C CD  . PRO D 1 325 ? 170.663 113.422 99.172  1.00 85.54  ? 325 PRO D CD  1 
ATOM   16595 N N   . LEU D 1 326 ? 169.909 116.112 101.809 1.00 82.88  ? 326 LEU D N   1 
ATOM   16596 C CA  . LEU D 1 326 ? 169.494 117.301 102.550 1.00 81.48  ? 326 LEU D CA  1 
ATOM   16597 C C   . LEU D 1 326 ? 168.299 117.017 103.473 1.00 83.38  ? 326 LEU D C   1 
ATOM   16598 O O   . LEU D 1 326 ? 167.912 117.882 104.250 1.00 83.24  ? 326 LEU D O   1 
ATOM   16599 C CB  . LEU D 1 326 ? 169.188 118.458 101.581 1.00 80.38  ? 326 LEU D CB  1 
ATOM   16600 C CG  . LEU D 1 326 ? 170.307 118.820 100.596 1.00 78.88  ? 326 LEU D CG  1 
ATOM   16601 C CD1 . LEU D 1 326 ? 169.814 119.931 99.685  1.00 82.14  ? 326 LEU D CD1 1 
ATOM   16602 C CD2 . LEU D 1 326 ? 171.569 119.289 101.304 1.00 79.38  ? 326 LEU D CD2 1 
ATOM   16603 N N   . SER D 1 327 ? 167.694 115.831 103.422 1.00 79.70  ? 327 SER D N   1 
ATOM   16604 C CA  . SER D 1 327 ? 166.644 115.420 104.357 1.00 76.74  ? 327 SER D CA  1 
ATOM   16605 C C   . SER D 1 327 ? 167.196 115.214 105.766 1.00 75.60  ? 327 SER D C   1 
ATOM   16606 O O   . SER D 1 327 ? 168.336 114.786 105.947 1.00 71.05  ? 327 SER D O   1 
ATOM   16607 C CB  . SER D 1 327 ? 165.983 114.114 103.926 1.00 70.26  ? 327 SER D CB  1 
ATOM   16608 O OG  . SER D 1 327 ? 165.590 114.156 102.578 1.00 69.84  ? 327 SER D OG  1 
ATOM   16609 N N   . ARG D 1 328 ? 166.352 115.454 106.770 1.00 70.08  ? 328 ARG D N   1 
ATOM   16610 C CA  . ARG D 1 328 ? 166.508 114.925 108.128 1.00 63.43  ? 328 ARG D CA  1 
ATOM   16611 C C   . ARG D 1 328 ? 165.552 113.770 108.421 1.00 69.77  ? 328 ARG D C   1 
ATOM   16612 O O   . ARG D 1 328 ? 165.817 113.003 109.329 1.00 84.99  ? 328 ARG D O   1 
ATOM   16613 C CB  . ARG D 1 328 ? 166.325 116.040 109.162 1.00 63.15  ? 328 ARG D CB  1 
ATOM   16614 C CG  . ARG D 1 328 ? 167.441 117.085 109.125 1.00 63.99  ? 328 ARG D CG  1 
ATOM   16615 C CD  . ARG D 1 328 ? 167.442 117.934 110.400 1.00 71.03  ? 328 ARG D CD  1 
ATOM   16616 N NE  . ARG D 1 328 ? 167.982 117.195 111.554 1.00 68.65  ? 328 ARG D NE  1 
ATOM   16617 C CZ  . ARG D 1 328 ? 169.215 117.230 112.003 1.00 70.82  ? 328 ARG D CZ  1 
ATOM   16618 N NH1 . ARG D 1 328 ? 169.573 116.434 112.957 1.00 72.88  ? 328 ARG D NH1 1 
ATOM   16619 N NH2 . ARG D 1 328 ? 170.113 118.023 111.510 1.00 70.40  ? 328 ARG D NH2 1 
ATOM   16620 N N   . LYS D 1 329 ? 164.461 113.625 107.671 1.00 59.74  ? 329 LYS D N   1 
ATOM   16621 C CA  . LYS D 1 329 ? 163.474 112.542 107.760 1.00 54.97  ? 329 LYS D CA  1 
ATOM   16622 C C   . LYS D 1 329 ? 163.528 111.683 106.506 1.00 61.48  ? 329 LYS D C   1 
ATOM   16623 O O   . LYS D 1 329 ? 163.458 112.213 105.405 1.00 75.22  ? 329 LYS D O   1 
ATOM   16624 C CB  . LYS D 1 329 ? 162.094 113.178 107.926 1.00 59.57  ? 329 LYS D CB  1 
ATOM   16625 C CG  . LYS D 1 329 ? 160.920 112.196 107.962 1.00 57.47  ? 329 LYS D CG  1 
ATOM   16626 C CD  . LYS D 1 329 ? 159.611 112.984 107.898 1.00 59.91  ? 329 LYS D CD  1 
ATOM   16627 C CE  . LYS D 1 329 ? 158.407 112.055 107.992 1.00 66.45  ? 329 LYS D CE  1 
ATOM   16628 N NZ  . LYS D 1 329 ? 157.137 112.797 107.815 1.00 64.85  ? 329 LYS D NZ  1 
ATOM   16629 N N   . PHE D 1 330 ? 163.589 110.368 106.657 1.00 65.44  ? 330 PHE D N   1 
ATOM   16630 C CA  . PHE D 1 330 ? 163.542 109.411 105.554 1.00 66.30  ? 330 PHE D CA  1 
ATOM   16631 C C   . PHE D 1 330 ? 162.385 108.436 105.766 1.00 71.80  ? 330 PHE D C   1 
ATOM   16632 O O   . PHE D 1 330 ? 162.428 107.657 106.712 1.00 76.23  ? 330 PHE D O   1 
ATOM   16633 C CB  . PHE D 1 330 ? 164.885 108.670 105.474 1.00 63.24  ? 330 PHE D CB  1 
ATOM   16634 C CG  . PHE D 1 330 ? 166.094 109.577 105.416 1.00 69.94  ? 330 PHE D CG  1 
ATOM   16635 C CD1 . PHE D 1 330 ? 166.691 110.033 106.606 1.00 71.60  ? 330 PHE D CD1 1 
ATOM   16636 C CD2 . PHE D 1 330 ? 166.615 109.987 104.176 1.00 68.42  ? 330 PHE D CD2 1 
ATOM   16637 C CE1 . PHE D 1 330 ? 167.781 110.908 106.559 1.00 70.83  ? 330 PHE D CE1 1 
ATOM   16638 C CE2 . PHE D 1 330 ? 167.722 110.843 104.127 1.00 69.24  ? 330 PHE D CE2 1 
ATOM   16639 C CZ  . PHE D 1 330 ? 168.297 111.310 105.318 1.00 75.42  ? 330 PHE D CZ  1 
ATOM   16640 N N   . THR D 1 331 ? 161.361 108.434 104.917 1.00 77.85  ? 331 THR D N   1 
ATOM   16641 C CA  . THR D 1 331 ? 160.300 107.417 104.990 1.00 73.69  ? 331 THR D CA  1 
ATOM   16642 C C   . THR D 1 331 ? 160.872 106.043 104.649 1.00 70.69  ? 331 THR D C   1 
ATOM   16643 O O   . THR D 1 331 ? 161.391 105.837 103.556 1.00 75.83  ? 331 THR D O   1 
ATOM   16644 C CB  . THR D 1 331 ? 159.123 107.738 104.064 1.00 78.69  ? 331 THR D CB  1 
ATOM   16645 O OG1 . THR D 1 331 ? 158.571 108.995 104.375 1.00 80.96  ? 331 THR D OG1 1 
ATOM   16646 C CG2 . THR D 1 331 ? 157.991 106.727 104.221 1.00 75.64  ? 331 THR D CG2 1 
ATOM   16647 N N   . GLU D 1 332 ? 160.788 105.089 105.572 1.00 73.33  ? 332 GLU D N   1 
ATOM   16648 C CA  . GLU D 1 332 ? 161.263 103.719 105.396 1.00 75.72  ? 332 GLU D CA  1 
ATOM   16649 C C   . GLU D 1 332 ? 160.240 102.869 104.637 1.00 80.85  ? 332 GLU D C   1 
ATOM   16650 O O   . GLU D 1 332 ? 160.570 102.228 103.639 1.00 79.33  ? 332 GLU D O   1 
ATOM   16651 C CB  . GLU D 1 332 ? 161.577 103.114 106.771 1.00 72.89  ? 332 GLU D CB  1 
ATOM   16652 C CG  . GLU D 1 332 ? 162.123 101.692 106.632 1.00 80.28  ? 332 GLU D CG  1 
ATOM   16653 C CD  . GLU D 1 332 ? 162.417 101.026 107.974 1.00 88.18  ? 332 GLU D CD  1 
ATOM   16654 O OE1 . GLU D 1 332 ? 162.918 101.697 108.899 1.00 89.63  ? 332 GLU D OE1 1 
ATOM   16655 O OE2 . GLU D 1 332 ? 162.187 99.805  108.101 1.00 86.34  ? 332 GLU D OE2 1 
ATOM   16656 N N   . TRP D 1 333 ? 158.988 102.883 105.095 1.00 75.72  ? 333 TRP D N   1 
ATOM   16657 C CA  . TRP D 1 333 ? 157.843 102.314 104.390 1.00 69.12  ? 333 TRP D CA  1 
ATOM   16658 C C   . TRP D 1 333 ? 156.555 103.035 104.771 1.00 69.11  ? 333 TRP D C   1 
ATOM   16659 O O   . TRP D 1 333 ? 156.454 103.681 105.809 1.00 76.17  ? 333 TRP D O   1 
ATOM   16660 C CB  . TRP D 1 333 ? 157.748 100.794 104.598 1.00 68.11  ? 333 TRP D CB  1 
ATOM   16661 C CG  . TRP D 1 333 ? 157.559 100.260 105.986 1.00 68.38  ? 333 TRP D CG  1 
ATOM   16662 C CD1 . TRP D 1 333 ? 158.535 99.707  106.735 1.00 68.47  ? 333 TRP D CD1 1 
ATOM   16663 C CD2 . TRP D 1 333 ? 156.339 100.143 106.784 1.00 74.00  ? 333 TRP D CD2 1 
ATOM   16664 N NE1 . TRP D 1 333 ? 158.012 99.260  107.927 1.00 69.03  ? 333 TRP D NE1 1 
ATOM   16665 C CE2 . TRP D 1 333 ? 156.659 99.485  108.003 1.00 69.90  ? 333 TRP D CE2 1 
ATOM   16666 C CE3 . TRP D 1 333 ? 154.986 100.497 106.601 1.00 77.88  ? 333 TRP D CE3 1 
ATOM   16667 C CZ2 . TRP D 1 333 ? 155.699 99.200  108.979 1.00 66.92  ? 333 TRP D CZ2 1 
ATOM   16668 C CZ3 . TRP D 1 333 ? 154.019 100.239 107.588 1.00 69.62  ? 333 TRP D CZ3 1 
ATOM   16669 C CH2 . TRP D 1 333 ? 154.369 99.583  108.772 1.00 68.74  ? 333 TRP D CH2 1 
ATOM   16670 N N   . CYS D 1 334 ? 155.555 102.925 103.912 1.00 77.58  ? 334 CYS D N   1 
ATOM   16671 C CA  . CYS D 1 334 ? 154.212 103.438 104.124 1.00 77.52  ? 334 CYS D CA  1 
ATOM   16672 C C   . CYS D 1 334 ? 153.196 102.384 103.674 1.00 82.08  ? 334 CYS D C   1 
ATOM   16673 O O   . CYS D 1 334 ? 153.346 101.792 102.600 1.00 86.72  ? 334 CYS D O   1 
ATOM   16674 C CB  . CYS D 1 334 ? 154.083 104.759 103.364 1.00 82.34  ? 334 CYS D CB  1 
ATOM   16675 S SG  . CYS D 1 334 ? 152.416 105.432 103.538 1.00 93.31  ? 334 CYS D SG  1 
ATOM   16676 N N   . TYR D 1 335 ? 152.179 102.129 104.491 1.00 73.79  ? 335 TYR D N   1 
ATOM   16677 C CA  . TYR D 1 335 ? 151.150 101.129 104.223 1.00 75.48  ? 335 TYR D CA  1 
ATOM   16678 C C   . TYR D 1 335 ? 149.836 101.534 104.885 1.00 74.68  ? 335 TYR D C   1 
ATOM   16679 O O   . TYR D 1 335 ? 149.717 101.549 106.109 1.00 77.59  ? 335 TYR D O   1 
ATOM   16680 C CB  . TYR D 1 335 ? 151.627 99.749  104.685 1.00 76.01  ? 335 TYR D CB  1 
ATOM   16681 C CG  . TYR D 1 335 ? 150.729 98.613  104.255 1.00 77.75  ? 335 TYR D CG  1 
ATOM   16682 C CD1 . TYR D 1 335 ? 150.895 98.024  102.989 1.00 78.66  ? 335 TYR D CD1 1 
ATOM   16683 C CD2 . TYR D 1 335 ? 149.714 98.156  105.106 1.00 72.59  ? 335 TYR D CD2 1 
ATOM   16684 C CE1 . TYR D 1 335 ? 150.027 97.007  102.568 1.00 76.74  ? 335 TYR D CE1 1 
ATOM   16685 C CE2 . TYR D 1 335 ? 148.850 97.129  104.691 1.00 72.75  ? 335 TYR D CE2 1 
ATOM   16686 C CZ  . TYR D 1 335 ? 148.991 96.567  103.412 1.00 77.48  ? 335 TYR D CZ  1 
ATOM   16687 O OH  . TYR D 1 335 ? 148.118 95.618  102.998 1.00 79.17  ? 335 TYR D OH  1 
ATOM   16688 N N   . GLY D 1 336 ? 148.843 101.897 104.086 1.00 73.00  ? 336 GLY D N   1 
ATOM   16689 C CA  . GLY D 1 336 ? 147.581 102.410 104.581 1.00 74.84  ? 336 GLY D CA  1 
ATOM   16690 C C   . GLY D 1 336 ? 147.807 103.691 105.388 1.00 77.83  ? 336 GLY D C   1 
ATOM   16691 O O   . GLY D 1 336 ? 148.586 104.539 104.957 1.00 79.79  ? 336 GLY D O   1 
ATOM   16692 N N   . PRO D 1 337 ? 147.179 103.857 106.560 1.00 77.11  ? 337 PRO D N   1 
ATOM   16693 C CA  . PRO D 1 337 ? 147.325 105.039 107.395 1.00 77.58  ? 337 PRO D CA  1 
ATOM   16694 C C   . PRO D 1 337 ? 148.676 105.108 108.119 1.00 81.45  ? 337 PRO D C   1 
ATOM   16695 O O   . PRO D 1 337 ? 148.904 106.059 108.864 1.00 80.76  ? 337 PRO D O   1 
ATOM   16696 C CB  . PRO D 1 337 ? 146.153 104.959 108.371 1.00 69.71  ? 337 PRO D CB  1 
ATOM   16697 C CG  . PRO D 1 337 ? 145.984 103.465 108.564 1.00 73.21  ? 337 PRO D CG  1 
ATOM   16698 C CD  . PRO D 1 337 ? 146.280 102.916 107.180 1.00 72.39  ? 337 PRO D CD  1 
ATOM   16699 N N   . VAL D 1 338 ? 149.558 104.121 107.945 1.00 83.39  ? 338 VAL D N   1 
ATOM   16700 C CA  . VAL D 1 338 ? 150.792 103.968 108.718 1.00 80.52  ? 338 VAL D CA  1 
ATOM   16701 C C   . VAL D 1 338 ? 152.000 104.395 107.900 1.00 80.90  ? 338 VAL D C   1 
ATOM   16702 O O   . VAL D 1 338 ? 152.253 103.845 106.831 1.00 82.96  ? 338 VAL D O   1 
ATOM   16703 C CB  . VAL D 1 338 ? 150.978 102.522 109.208 1.00 74.15  ? 338 VAL D CB  1 
ATOM   16704 C CG1 . VAL D 1 338 ? 152.115 102.452 110.230 1.00 74.68  ? 338 VAL D CG1 1 
ATOM   16705 C CG2 . VAL D 1 338 ? 149.689 101.974 109.822 1.00 71.64  ? 338 VAL D CG2 1 
ATOM   16706 N N   . ARG D 1 339 ? 152.786 105.338 108.424 1.00 81.97  ? 339 ARG D N   1 
ATOM   16707 C CA  . ARG D 1 339 ? 154.107 105.703 107.907 1.00 82.30  ? 339 ARG D CA  1 
ATOM   16708 C C   . ARG D 1 339 ? 155.171 105.331 108.921 1.00 81.74  ? 339 ARG D C   1 
ATOM   16709 O O   . ARG D 1 339 ? 155.050 105.695 110.083 1.00 90.00  ? 339 ARG D O   1 
ATOM   16710 C CB  . ARG D 1 339 ? 154.192 107.205 107.620 1.00 84.63  ? 339 ARG D CB  1 
ATOM   16711 C CG  . ARG D 1 339 ? 153.164 107.682 106.590 1.00 88.26  ? 339 ARG D CG  1 
ATOM   16712 C CD  . ARG D 1 339 ? 153.435 109.124 106.157 1.00 86.21  ? 339 ARG D CD  1 
ATOM   16713 N NE  . ARG D 1 339 ? 154.640 109.221 105.307 1.00 90.05  ? 339 ARG D NE  1 
ATOM   16714 C CZ  . ARG D 1 339 ? 154.679 109.298 103.989 1.00 93.03  ? 339 ARG D CZ  1 
ATOM   16715 N NH1 . ARG D 1 339 ? 155.817 109.378 103.366 1.00 91.10  ? 339 ARG D NH1 1 
ATOM   16716 N NH2 . ARG D 1 339 ? 153.605 109.298 103.256 1.00 93.48  ? 339 ARG D NH2 1 
ATOM   16717 N N   . VAL D 1 340 ? 156.241 104.678 108.493 1.00 68.47  ? 340 VAL D N   1 
ATOM   16718 C CA  . VAL D 1 340 ? 157.441 104.478 109.310 1.00 66.56  ? 340 VAL D CA  1 
ATOM   16719 C C   . VAL D 1 340 ? 158.566 105.333 108.751 1.00 75.70  ? 340 VAL D C   1 
ATOM   16720 O O   . VAL D 1 340 ? 158.874 105.247 107.568 1.00 85.22  ? 340 VAL D O   1 
ATOM   16721 C CB  . VAL D 1 340 ? 157.806 102.995 109.393 1.00 64.03  ? 340 VAL D CB  1 
ATOM   16722 C CG1 . VAL D 1 340 ? 159.065 102.780 110.229 1.00 70.34  ? 340 VAL D CG1 1 
ATOM   16723 C CG2 . VAL D 1 340 ? 156.647 102.244 110.045 1.00 73.70  ? 340 VAL D CG2 1 
ATOM   16724 N N   . SER D 1 341 ? 159.177 106.177 109.580 1.00 70.89  ? 341 SER D N   1 
ATOM   16725 C CA  . SER D 1 341 ? 160.204 107.136 109.170 1.00 65.48  ? 341 SER D CA  1 
ATOM   16726 C C   . SER D 1 341 ? 161.422 107.065 110.071 1.00 67.10  ? 341 SER D C   1 
ATOM   16727 O O   . SER D 1 341 ? 161.291 107.008 111.286 1.00 82.65  ? 341 SER D O   1 
ATOM   16728 C CB  . SER D 1 341 ? 159.675 108.566 109.206 1.00 68.13  ? 341 SER D CB  1 
ATOM   16729 O OG  . SER D 1 341 ? 158.521 108.717 108.411 1.00 78.86  ? 341 SER D OG  1 
ATOM   16730 N N   . LEU D 1 342 ? 162.611 107.136 109.491 1.00 61.67  ? 342 LEU D N   1 
ATOM   16731 C CA  . LEU D 1 342 ? 163.861 107.376 110.198 1.00 58.61  ? 342 LEU D CA  1 
ATOM   16732 C C   . LEU D 1 342 ? 164.099 108.880 110.306 1.00 59.97  ? 342 LEU D C   1 
ATOM   16733 O O   . LEU D 1 342 ? 164.127 109.562 109.292 1.00 71.36  ? 342 LEU D O   1 
ATOM   16734 C CB  . LEU D 1 342 ? 165.001 106.727 109.403 1.00 64.04  ? 342 LEU D CB  1 
ATOM   16735 C CG  . LEU D 1 342 ? 164.943 105.202 109.297 1.00 60.17  ? 342 LEU D CG  1 
ATOM   16736 C CD1 . LEU D 1 342 ? 166.112 104.723 108.448 1.00 68.02  ? 342 LEU D CD1 1 
ATOM   16737 C CD2 . LEU D 1 342 ? 165.031 104.532 110.661 1.00 60.14  ? 342 LEU D CD2 1 
ATOM   16738 N N   . TYR D 1 343 ? 164.291 109.407 111.507 1.00 57.47  ? 343 TYR D N   1 
ATOM   16739 C CA  . TYR D 1 343 ? 164.662 110.798 111.749 1.00 58.15  ? 343 TYR D CA  1 
ATOM   16740 C C   . TYR D 1 343 ? 166.120 110.904 112.199 1.00 67.60  ? 343 TYR D C   1 
ATOM   16741 O O   . TYR D 1 343 ? 166.560 110.166 113.069 1.00 75.03  ? 343 TYR D O   1 
ATOM   16742 C CB  . TYR D 1 343 ? 163.737 111.397 112.797 1.00 56.61  ? 343 TYR D CB  1 
ATOM   16743 C CG  . TYR D 1 343 ? 162.328 111.694 112.332 1.00 52.20  ? 343 TYR D CG  1 
ATOM   16744 C CD1 . TYR D 1 343 ? 161.328 110.713 112.421 1.00 55.58  ? 343 TYR D CD1 1 
ATOM   16745 C CD2 . TYR D 1 343 ? 162.003 112.985 111.893 1.00 56.32  ? 343 TYR D CD2 1 
ATOM   16746 C CE1 . TYR D 1 343 ? 159.997 111.042 112.107 1.00 61.52  ? 343 TYR D CE1 1 
ATOM   16747 C CE2 . TYR D 1 343 ? 160.671 113.317 111.604 1.00 59.31  ? 343 TYR D CE2 1 
ATOM   16748 C CZ  . TYR D 1 343 ? 159.660 112.350 111.736 1.00 61.95  ? 343 TYR D CZ  1 
ATOM   16749 O OH  . TYR D 1 343 ? 158.363 112.666 111.500 1.00 62.91  ? 343 TYR D OH  1 
ATOM   16750 N N   . ASP D 1 344 ? 166.879 111.824 111.623 1.00 71.01  ? 344 ASP D N   1 
ATOM   16751 C CA  . ASP D 1 344 ? 168.285 112.095 111.912 1.00 69.50  ? 344 ASP D CA  1 
ATOM   16752 C C   . ASP D 1 344 ? 168.472 112.878 113.227 1.00 72.06  ? 344 ASP D C   1 
ATOM   16753 O O   . ASP D 1 344 ? 168.017 114.017 113.346 1.00 78.52  ? 344 ASP D O   1 
ATOM   16754 C CB  . ASP D 1 344 ? 168.819 112.869 110.705 1.00 72.25  ? 344 ASP D CB  1 
ATOM   16755 C CG  . ASP D 1 344 ? 170.283 113.275 110.790 1.00 71.87  ? 344 ASP D CG  1 
ATOM   16756 O OD1 . ASP D 1 344 ? 170.963 112.898 111.766 1.00 76.52  ? 344 ASP D OD1 1 
ATOM   16757 O OD2 . ASP D 1 344 ? 170.738 113.949 109.843 1.00 63.91  ? 344 ASP D OD2 1 
ATOM   16758 N N   . LEU D 1 345 ? 169.154 112.290 114.216 1.00 66.69  ? 345 LEU D N   1 
ATOM   16759 C CA  . LEU D 1 345 ? 169.318 112.857 115.555 1.00 60.02  ? 345 LEU D CA  1 
ATOM   16760 C C   . LEU D 1 345 ? 170.618 113.651 115.782 1.00 60.34  ? 345 LEU D C   1 
ATOM   16761 O O   . LEU D 1 345 ? 170.929 113.962 116.929 1.00 70.84  ? 345 LEU D O   1 
ATOM   16762 C CB  . LEU D 1 345 ? 169.165 111.755 116.616 1.00 61.42  ? 345 LEU D CB  1 
ATOM   16763 C CG  . LEU D 1 345 ? 167.814 111.038 116.691 1.00 57.89  ? 345 LEU D CG  1 
ATOM   16764 C CD1 . LEU D 1 345 ? 167.770 110.278 118.011 1.00 68.00  ? 345 LEU D CD1 1 
ATOM   16765 C CD2 . LEU D 1 345 ? 166.628 111.994 116.667 1.00 65.68  ? 345 LEU D CD2 1 
ATOM   16766 N N   . SER D 1 346 ? 171.378 114.004 114.743 1.00 65.68  ? 346 SER D N   1 
ATOM   16767 C CA  . SER D 1 346 ? 172.753 114.530 114.858 1.00 73.41  ? 346 SER D CA  1 
ATOM   16768 C C   . SER D 1 346 ? 172.965 115.642 115.903 1.00 79.54  ? 346 SER D C   1 
ATOM   16769 O O   . SER D 1 346 ? 173.724 115.453 116.852 1.00 84.43  ? 346 SER D O   1 
ATOM   16770 C CB  . SER D 1 346 ? 173.265 114.976 113.487 1.00 73.10  ? 346 SER D CB  1 
ATOM   16771 O OG  . SER D 1 346 ? 172.489 116.033 112.942 1.00 71.95  ? 346 SER D OG  1 
ATOM   16772 N N   . SER D 1 347 ? 172.279 116.779 115.780 1.00 67.78  ? 347 SER D N   1 
ATOM   16773 C CA  . SER D 1 347 ? 172.285 117.880 116.748 1.00 60.97  ? 347 SER D CA  1 
ATOM   16774 C C   . SER D 1 347 ? 171.288 117.716 117.898 1.00 67.38  ? 347 SER D C   1 
ATOM   16775 O O   . SER D 1 347 ? 171.176 118.617 118.726 1.00 77.64  ? 347 SER D O   1 
ATOM   16776 C CB  . SER D 1 347 ? 171.955 119.190 116.023 1.00 67.47  ? 347 SER D CB  1 
ATOM   16777 O OG  . SER D 1 347 ? 172.761 119.384 114.877 1.00 70.30  ? 347 SER D OG  1 
ATOM   16778 N N   . VAL D 1 348 ? 170.492 116.645 117.916 1.00 67.71  ? 348 VAL D N   1 
ATOM   16779 C CA  . VAL D 1 348 ? 169.242 116.544 118.684 1.00 61.35  ? 348 VAL D CA  1 
ATOM   16780 C C   . VAL D 1 348 ? 169.368 115.740 119.974 1.00 59.48  ? 348 VAL D C   1 
ATOM   16781 O O   . VAL D 1 348 ? 168.849 116.172 120.996 1.00 63.30  ? 348 VAL D O   1 
ATOM   16782 C CB  . VAL D 1 348 ? 168.096 116.019 117.801 1.00 61.56  ? 348 VAL D CB  1 
ATOM   16783 C CG1 . VAL D 1 348 ? 166.772 115.901 118.551 1.00 59.46  ? 348 VAL D CG1 1 
ATOM   16784 C CG2 . VAL D 1 348 ? 167.837 116.934 116.601 1.00 61.42  ? 348 VAL D CG2 1 
ATOM   16785 N N   . ASP D 1 349 ? 170.021 114.584 119.916 1.00 74.71  ? 349 ASP D N   1 
ATOM   16786 C CA  . ASP D 1 349 ? 170.144 113.697 121.066 1.00 77.73  ? 349 ASP D CA  1 
ATOM   16787 C C   . ASP D 1 349 ? 171.042 114.326 122.141 1.00 88.05  ? 349 ASP D C   1 
ATOM   16788 O O   . ASP D 1 349 ? 172.128 114.833 121.863 1.00 88.56  ? 349 ASP D O   1 
ATOM   16789 C CB  . ASP D 1 349 ? 170.649 112.322 120.614 1.00 73.42  ? 349 ASP D CB  1 
ATOM   16790 C CG  . ASP D 1 349 ? 170.683 111.279 121.740 1.00 86.49  ? 349 ASP D CG  1 
ATOM   16791 O OD1 . ASP D 1 349 ? 170.007 111.486 122.777 1.00 86.69  ? 349 ASP D OD1 1 
ATOM   16792 O OD2 . ASP D 1 349 ? 171.400 110.272 121.568 1.00 90.94  ? 349 ASP D OD2 1 
ATOM   16793 N N   . SER D 1 350 ? 170.600 114.248 123.391 1.00 85.64  ? 350 SER D N   1 
ATOM   16794 C CA  . SER D 1 350 ? 171.232 114.809 124.582 1.00 78.85  ? 350 SER D CA  1 
ATOM   16795 C C   . SER D 1 350 ? 172.562 114.158 124.970 1.00 74.93  ? 350 SER D C   1 
ATOM   16796 O O   . SER D 1 350 ? 173.230 114.620 125.896 1.00 78.80  ? 350 SER D O   1 
ATOM   16797 C CB  . SER D 1 350 ? 170.221 114.730 125.717 1.00 82.47  ? 350 SER D CB  1 
ATOM   16798 O OG  . SER D 1 350 ? 169.731 113.417 125.829 1.00 86.56  ? 350 SER D OG  1 
ATOM   16799 N N   . TRP D 1 351 ? 172.979 113.117 124.255 1.00 82.44  ? 351 TRP D N   1 
ATOM   16800 C CA  . TRP D 1 351 ? 174.335 112.576 124.266 1.00 85.36  ? 351 TRP D CA  1 
ATOM   16801 C C   . TRP D 1 351 ? 175.387 113.626 123.874 1.00 89.91  ? 351 TRP D C   1 
ATOM   16802 O O   . TRP D 1 351 ? 176.473 113.662 124.447 1.00 91.59  ? 351 TRP D O   1 
ATOM   16803 C CB  . TRP D 1 351 ? 174.343 111.376 123.312 1.00 84.69  ? 351 TRP D CB  1 
ATOM   16804 C CG  . TRP D 1 351 ? 175.660 110.719 123.071 1.00 89.69  ? 351 TRP D CG  1 
ATOM   16805 C CD1 . TRP D 1 351 ? 176.152 109.677 123.775 1.00 91.81  ? 351 TRP D CD1 1 
ATOM   16806 C CD2 . TRP D 1 351 ? 176.669 111.039 122.068 1.00 93.15  ? 351 TRP D CD2 1 
ATOM   16807 N NE1 . TRP D 1 351 ? 177.393 109.333 123.286 1.00 89.85  ? 351 TRP D NE1 1 
ATOM   16808 C CE2 . TRP D 1 351 ? 177.764 110.138 122.231 1.00 90.81  ? 351 TRP D CE2 1 
ATOM   16809 C CE3 . TRP D 1 351 ? 176.770 111.984 121.026 1.00 92.06  ? 351 TRP D CE3 1 
ATOM   16810 C CZ2 . TRP D 1 351 ? 178.902 110.184 121.418 1.00 86.56  ? 351 TRP D CZ2 1 
ATOM   16811 C CZ3 . TRP D 1 351 ? 177.914 112.044 120.207 1.00 90.74  ? 351 TRP D CZ3 1 
ATOM   16812 C CH2 . TRP D 1 351 ? 178.978 111.150 120.403 1.00 87.77  ? 351 TRP D CH2 1 
ATOM   16813 N N   . GLU D 1 352 ? 175.057 114.524 122.944 1.00 95.32  ? 352 GLU D N   1 
ATOM   16814 C CA  . GLU D 1 352 ? 175.883 115.682 122.588 1.00 95.96  ? 352 GLU D CA  1 
ATOM   16815 C C   . GLU D 1 352 ? 175.688 116.849 123.576 1.00 97.84  ? 352 GLU D C   1 
ATOM   16816 O O   . GLU D 1 352 ? 174.558 117.222 123.911 1.00 99.88  ? 352 GLU D O   1 
ATOM   16817 C CB  . GLU D 1 352 ? 175.586 116.082 121.129 1.00 91.70  ? 352 GLU D CB  1 
ATOM   16818 N N   . LYS D 1 353 ? 176.787 117.477 124.007 1.00 89.28  ? 353 LYS D N   1 
ATOM   16819 C CA  . LYS D 1 353 ? 176.770 118.717 124.800 1.00 89.62  ? 353 LYS D CA  1 
ATOM   16820 C C   . LYS D 1 353 ? 176.263 119.887 123.960 1.00 93.23  ? 353 LYS D C   1 
ATOM   16821 O O   . LYS D 1 353 ? 176.648 120.004 122.799 1.00 91.67  ? 353 LYS D O   1 
ATOM   16822 C CB  . LYS D 1 353 ? 178.180 119.015 125.336 1.00 91.53  ? 353 LYS D CB  1 
ATOM   16823 C CG  . LYS D 1 353 ? 178.692 117.945 126.309 1.00 94.52  ? 353 LYS D CG  1 
ATOM   16824 C CD  . LYS D 1 353 ? 180.110 118.275 126.783 1.00 95.05  ? 353 LYS D CD  1 
ATOM   16825 C CE  . LYS D 1 353 ? 180.625 117.176 127.712 1.00 93.52  ? 353 LYS D CE  1 
ATOM   16826 N NZ  . LYS D 1 353 ? 182.013 117.436 128.153 1.00 95.07  ? 353 LYS D NZ  1 
ATOM   16827 N N   . ASN D 1 354 ? 175.443 120.777 124.523 1.00 81.99  ? 354 ASN D N   1 
ATOM   16828 C CA  . ASN D 1 354 ? 174.805 121.875 123.781 1.00 78.89  ? 354 ASN D CA  1 
ATOM   16829 C C   . ASN D 1 354 ? 173.948 121.378 122.599 1.00 79.07  ? 354 ASN D C   1 
ATOM   16830 O O   . ASN D 1 354 ? 174.036 121.878 121.480 1.00 85.90  ? 354 ASN D O   1 
ATOM   16831 C CB  . ASN D 1 354 ? 175.860 122.939 123.420 1.00 86.04  ? 354 ASN D CB  1 
ATOM   16832 C CG  . ASN D 1 354 ? 175.256 124.228 122.900 1.00 90.81  ? 354 ASN D CG  1 
ATOM   16833 O OD1 . ASN D 1 354 ? 174.234 124.692 123.377 1.00 88.85  ? 354 ASN D OD1 1 
ATOM   16834 N ND2 . ASN D 1 354 ? 175.878 124.858 121.935 1.00 84.37  ? 354 ASN D ND2 1 
ATOM   16835 N N   . SER D 1 355 ? 173.172 120.316 122.801 1.00 69.85  ? 355 SER D N   1 
ATOM   16836 C CA  . SER D 1 355 ? 172.213 119.767 121.836 1.00 59.36  ? 355 SER D CA  1 
ATOM   16837 C C   . SER D 1 355 ? 170.860 120.479 121.889 1.00 62.73  ? 355 SER D C   1 
ATOM   16838 O O   . SER D 1 355 ? 170.562 121.219 122.817 1.00 78.13  ? 355 SER D O   1 
ATOM   16839 C CB  . SER D 1 355 ? 172.036 118.271 122.088 1.00 59.88  ? 355 SER D CB  1 
ATOM   16840 O OG  . SER D 1 355 ? 171.890 118.013 123.465 1.00 60.43  ? 355 SER D OG  1 
ATOM   16841 N N   . VAL D 1 356 ? 170.014 120.249 120.890 1.00 46.41  ? 356 VAL D N   1 
ATOM   16842 C CA  . VAL D 1 356 ? 168.681 120.870 120.747 1.00 39.39  ? 356 VAL D CA  1 
ATOM   16843 C C   . VAL D 1 356 ? 167.773 120.616 121.950 1.00 46.49  ? 356 VAL D C   1 
ATOM   16844 O O   . VAL D 1 356 ? 167.016 121.496 122.334 1.00 70.73  ? 356 VAL D O   1 
ATOM   16845 C CB  . VAL D 1 356 ? 168.011 120.386 119.451 1.00 49.47  ? 356 VAL D CB  1 
ATOM   16846 C CG1 . VAL D 1 356 ? 166.522 120.673 119.320 1.00 52.94  ? 356 VAL D CG1 1 
ATOM   16847 C CG2 . VAL D 1 356 ? 168.696 120.999 118.231 1.00 52.81  ? 356 VAL D CG2 1 
ATOM   16848 N N   . LEU D 1 357 ? 167.829 119.433 122.556 1.00 60.77  ? 357 LEU D N   1 
ATOM   16849 C CA  . LEU D 1 357 ? 167.039 119.135 123.747 1.00 56.43  ? 357 LEU D CA  1 
ATOM   16850 C C   . LEU D 1 357 ? 167.500 119.955 124.959 1.00 62.16  ? 357 LEU D C   1 
ATOM   16851 O O   . LEU D 1 357 ? 166.674 120.537 125.653 1.00 67.67  ? 357 LEU D O   1 
ATOM   16852 C CB  . LEU D 1 357 ? 167.101 117.626 124.021 1.00 57.65  ? 357 LEU D CB  1 
ATOM   16853 C CG  . LEU D 1 357 ? 166.311 116.762 123.030 1.00 64.38  ? 357 LEU D CG  1 
ATOM   16854 C CD1 . LEU D 1 357 ? 166.514 115.296 123.393 1.00 67.91  ? 357 LEU D CD1 1 
ATOM   16855 C CD2 . LEU D 1 357 ? 164.821 117.080 123.087 1.00 61.92  ? 357 LEU D CD2 1 
ATOM   16856 N N   . GLU D 1 358 ? 168.810 120.069 125.189 1.00 74.43  ? 358 GLU D N   1 
ATOM   16857 C CA  . GLU D 1 358 ? 169.376 120.930 126.229 1.00 66.70  ? 358 GLU D CA  1 
ATOM   16858 C C   . GLU D 1 358 ? 169.011 122.404 126.017 1.00 67.83  ? 358 GLU D C   1 
ATOM   16859 O O   . GLU D 1 358 ? 168.614 123.094 126.948 1.00 83.17  ? 358 GLU D O   1 
ATOM   16860 C CB  . GLU D 1 358 ? 170.896 120.713 126.286 1.00 69.92  ? 358 GLU D CB  1 
ATOM   16861 C CG  . GLU D 1 358 ? 171.614 121.705 127.205 1.00 82.75  ? 358 GLU D CG  1 
ATOM   16862 C CD  . GLU D 1 358 ? 172.946 121.170 127.740 1.00 86.70  ? 358 GLU D CD  1 
ATOM   16863 O OE1 . GLU D 1 358 ? 173.811 120.768 126.933 1.00 86.01  ? 358 GLU D OE1 1 
ATOM   16864 O OE2 . GLU D 1 358 ? 173.120 121.167 128.980 1.00 85.48  ? 358 GLU D OE2 1 
ATOM   16865 N N   . ILE D 1 359 ? 169.065 122.879 124.781 1.00 59.62  ? 359 ILE D N   1 
ATOM   16866 C CA  . ILE D 1 359 ? 168.693 124.234 124.369 1.00 55.03  ? 359 ILE D CA  1 
ATOM   16867 C C   . ILE D 1 359 ? 167.226 124.550 124.659 1.00 61.96  ? 359 ILE D C   1 
ATOM   16868 O O   . ILE D 1 359 ? 166.954 125.568 125.286 1.00 84.17  ? 359 ILE D O   1 
ATOM   16869 C CB  . ILE D 1 359 ? 169.051 124.478 122.890 1.00 49.39  ? 359 ILE D CB  1 
ATOM   16870 C CG1 . ILE D 1 359 ? 170.578 124.588 122.740 1.00 56.90  ? 359 ILE D CG1 1 
ATOM   16871 C CG2 . ILE D 1 359 ? 168.394 125.753 122.352 1.00 58.96  ? 359 ILE D CG2 1 
ATOM   16872 C CD1 . ILE D 1 359 ? 171.062 124.530 121.298 1.00 56.10  ? 359 ILE D CD1 1 
ATOM   16873 N N   . ILE D 1 360 ? 166.268 123.717 124.255 1.00 57.87  ? 360 ILE D N   1 
ATOM   16874 C CA  . ILE D 1 360 ? 164.842 123.973 124.512 1.00 52.91  ? 360 ILE D CA  1 
ATOM   16875 C C   . ILE D 1 360 ? 164.564 123.997 126.014 1.00 65.30  ? 360 ILE D C   1 
ATOM   16876 O O   . ILE D 1 360 ? 163.832 124.860 126.498 1.00 77.56  ? 360 ILE D O   1 
ATOM   16877 C CB  . ILE D 1 360 ? 163.950 122.929 123.814 1.00 59.37  ? 360 ILE D CB  1 
ATOM   16878 C CG1 . ILE D 1 360 ? 164.069 123.051 122.288 1.00 58.80  ? 360 ILE D CG1 1 
ATOM   16879 C CG2 . ILE D 1 360 ? 162.481 123.082 124.234 1.00 59.81  ? 360 ILE D CG2 1 
ATOM   16880 C CD1 . ILE D 1 360 ? 163.602 121.796 121.561 1.00 57.86  ? 360 ILE D CD1 1 
ATOM   16881 N N   . ALA D 1 361 ? 165.144 123.060 126.753 1.00 64.11  ? 361 ALA D N   1 
ATOM   16882 C CA  . ALA D 1 361 ? 164.946 122.981 128.180 1.00 63.38  ? 361 ALA D CA  1 
ATOM   16883 C C   . ALA D 1 361 ? 165.575 124.187 128.901 1.00 64.22  ? 361 ALA D C   1 
ATOM   16884 O O   . ALA D 1 361 ? 164.890 124.845 129.674 1.00 67.29  ? 361 ALA D O   1 
ATOM   16885 C CB  . ALA D 1 361 ? 165.489 121.636 128.647 1.00 68.50  ? 361 ALA D CB  1 
ATOM   16886 N N   . PHE D 1 362 ? 166.841 124.510 128.625 1.00 72.86  ? 362 PHE D N   1 
ATOM   16887 C CA  . PHE D 1 362 ? 167.649 125.363 129.500 1.00 76.37  ? 362 PHE D CA  1 
ATOM   16888 C C   . PHE D 1 362 ? 168.172 126.669 128.889 1.00 76.15  ? 362 PHE D C   1 
ATOM   16889 O O   . PHE D 1 362 ? 168.550 127.556 129.648 1.00 85.79  ? 362 PHE D O   1 
ATOM   16890 C CB  . PHE D 1 362 ? 168.816 124.529 130.045 1.00 72.17  ? 362 PHE D CB  1 
ATOM   16891 C CG  . PHE D 1 362 ? 168.390 123.260 130.755 1.00 74.14  ? 362 PHE D CG  1 
ATOM   16892 C CD1 . PHE D 1 362 ? 167.731 123.331 131.992 1.00 79.87  ? 362 PHE D CD1 1 
ATOM   16893 C CD2 . PHE D 1 362 ? 168.626 122.009 130.170 1.00 74.99  ? 362 PHE D CD2 1 
ATOM   16894 C CE1 . PHE D 1 362 ? 167.293 122.157 132.625 1.00 75.55  ? 362 PHE D CE1 1 
ATOM   16895 C CE2 . PHE D 1 362 ? 168.181 120.835 130.799 1.00 76.61  ? 362 PHE D CE2 1 
ATOM   16896 C CZ  . PHE D 1 362 ? 167.505 120.911 132.020 1.00 75.45  ? 362 PHE D CZ  1 
ATOM   16897 N N   . HIS D 1 363 ? 168.236 126.827 127.565 1.00 68.85  ? 363 HIS D N   1 
ATOM   16898 C CA  . HIS D 1 363 ? 168.794 128.033 126.929 1.00 73.14  ? 363 HIS D CA  1 
ATOM   16899 C C   . HIS D 1 363 ? 167.755 128.895 126.205 1.00 76.67  ? 363 HIS D C   1 
ATOM   16900 O O   . HIS D 1 363 ? 168.000 130.072 125.961 1.00 77.65  ? 363 HIS D O   1 
ATOM   16901 C CB  . HIS D 1 363 ? 169.908 127.665 125.947 1.00 69.08  ? 363 HIS D CB  1 
ATOM   16902 C CG  . HIS D 1 363 ? 171.033 126.815 126.473 1.00 70.97  ? 363 HIS D CG  1 
ATOM   16903 N ND1 . HIS D 1 363 ? 171.985 126.214 125.657 1.00 83.77  ? 363 HIS D ND1 1 
ATOM   16904 C CD2 . HIS D 1 363 ? 171.344 126.545 127.770 1.00 78.05  ? 363 HIS D CD2 1 
ATOM   16905 C CE1 . HIS D 1 363 ? 172.824 125.563 126.475 1.00 79.97  ? 363 HIS D CE1 1 
ATOM   16906 N NE2 . HIS D 1 363 ? 172.462 125.745 127.752 1.00 80.44  ? 363 HIS D NE2 1 
ATOM   16907 N N   . CYS D 1 364 ? 166.609 128.332 125.848 1.00 70.95  ? 364 CYS D N   1 
ATOM   16908 C CA  . CYS D 1 364 ? 165.501 129.027 125.213 1.00 73.86  ? 364 CYS D CA  1 
ATOM   16909 C C   . CYS D 1 364 ? 164.718 129.885 126.225 1.00 80.60  ? 364 CYS D C   1 
ATOM   16910 O O   . CYS D 1 364 ? 164.325 129.378 127.267 1.00 78.85  ? 364 CYS D O   1 
ATOM   16911 C CB  . CYS D 1 364 ? 164.630 127.947 124.568 1.00 67.86  ? 364 CYS D CB  1 
ATOM   16912 S SG  . CYS D 1 364 ? 163.304 128.677 123.587 1.00 80.65  ? 364 CYS D SG  1 
ATOM   16913 N N   . LYS D 1 365 ? 164.446 131.168 125.936 1.00 90.59  ? 365 LYS D N   1 
ATOM   16914 C CA  . LYS D 1 365 ? 163.652 132.074 126.801 1.00 86.95  ? 365 LYS D CA  1 
ATOM   16915 C C   . LYS D 1 365 ? 162.141 132.059 126.542 1.00 88.71  ? 365 LYS D C   1 
ATOM   16916 O O   . LYS D 1 365 ? 161.376 132.626 127.317 1.00 95.80  ? 365 LYS D O   1 
ATOM   16917 C CB  . LYS D 1 365 ? 164.143 133.523 126.631 1.00 92.54  ? 365 LYS D CB  1 
ATOM   16918 C CG  . LYS D 1 365 ? 165.542 133.763 127.193 1.00 96.30  ? 365 LYS D CG  1 
ATOM   16919 C CD  . LYS D 1 365 ? 165.916 135.243 127.131 1.00 96.76  ? 365 LYS D CD  1 
ATOM   16920 C CE  . LYS D 1 365 ? 167.292 135.466 127.746 1.00 94.99  ? 365 LYS D CE  1 
ATOM   16921 N NZ  . LYS D 1 365 ? 167.674 136.887 127.748 1.00 94.43  ? 365 LYS D NZ  1 
ATOM   16922 N N   . SER D 1 366 ? 161.707 131.519 125.409 1.00 78.55  ? 366 SER D N   1 
ATOM   16923 C CA  . SER D 1 366 ? 160.405 131.837 124.798 1.00 80.43  ? 366 SER D CA  1 
ATOM   16924 C C   . SER D 1 366 ? 159.200 131.118 125.425 1.00 79.96  ? 366 SER D C   1 
ATOM   16925 O O   . SER D 1 366 ? 159.345 130.027 125.975 1.00 79.27  ? 366 SER D O   1 
ATOM   16926 C CB  . SER D 1 366 ? 160.459 131.537 123.302 1.00 77.02  ? 366 SER D CB  1 
ATOM   16927 O OG  . SER D 1 366 ? 160.466 130.143 123.084 1.00 78.57  ? 366 SER D OG  1 
ATOM   16928 N N   . PRO D 1 367 ? 157.971 131.652 125.266 1.00 83.72  ? 367 PRO D N   1 
ATOM   16929 C CA  . PRO D 1 367 ? 156.734 130.932 125.580 1.00 79.89  ? 367 PRO D CA  1 
ATOM   16930 C C   . PRO D 1 367 ? 156.569 129.612 124.819 1.00 77.43  ? 367 PRO D C   1 
ATOM   16931 O O   . PRO D 1 367 ? 155.820 128.739 125.237 1.00 77.18  ? 367 PRO D O   1 
ATOM   16932 C CB  . PRO D 1 367 ? 155.600 131.884 125.191 1.00 79.48  ? 367 PRO D CB  1 
ATOM   16933 C CG  . PRO D 1 367 ? 156.236 133.262 125.255 1.00 79.05  ? 367 PRO D CG  1 
ATOM   16934 C CD  . PRO D 1 367 ? 157.669 133.000 124.822 1.00 79.60  ? 367 PRO D CD  1 
ATOM   16935 N N   . ASN D 1 368 ? 157.236 129.469 123.671 1.00 90.09  ? 368 ASN D N   1 
ATOM   16936 C CA  . ASN D 1 368 ? 157.069 128.381 122.704 1.00 84.24  ? 368 ASN D CA  1 
ATOM   16937 C C   . ASN D 1 368 ? 157.699 127.040 123.110 1.00 78.84  ? 368 ASN D C   1 
ATOM   16938 O O   . ASN D 1 368 ? 157.468 126.044 122.434 1.00 85.32  ? 368 ASN D O   1 
ATOM   16939 C CB  . ASN D 1 368 ? 157.657 128.847 121.359 1.00 82.28  ? 368 ASN D CB  1 
ATOM   16940 C CG  . ASN D 1 368 ? 156.787 129.848 120.622 1.00 82.34  ? 368 ASN D CG  1 
ATOM   16941 O OD1 . ASN D 1 368 ? 155.589 129.955 120.820 1.00 84.85  ? 368 ASN D OD1 1 
ATOM   16942 N ND2 . ASN D 1 368 ? 157.359 130.619 119.739 1.00 81.44  ? 368 ASN D ND2 1 
ATOM   16943 N N   . ARG D 1 369 ? 158.496 126.962 124.179 1.00 69.69  ? 369 ARG D N   1 
ATOM   16944 C CA  . ARG D 1 369 ? 159.260 125.751 124.538 1.00 69.13  ? 369 ARG D CA  1 
ATOM   16945 C C   . ARG D 1 369 ? 158.398 124.514 124.687 1.00 71.92  ? 369 ARG D C   1 
ATOM   16946 O O   . ARG D 1 369 ? 158.774 123.444 124.226 1.00 67.72  ? 369 ARG D O   1 
ATOM   16947 C CB  . ARG D 1 369 ? 160.005 126.000 125.847 1.00 71.99  ? 369 ARG D CB  1 
ATOM   16948 C CG  . ARG D 1 369 ? 161.168 126.953 125.626 1.00 70.51  ? 369 ARG D CG  1 
ATOM   16949 C CD  . ARG D 1 369 ? 161.581 127.610 126.930 1.00 76.54  ? 369 ARG D CD  1 
ATOM   16950 N NE  . ARG D 1 369 ? 162.092 126.648 127.914 1.00 70.13  ? 369 ARG D NE  1 
ATOM   16951 C CZ  . ARG D 1 369 ? 161.609 126.454 129.123 1.00 69.22  ? 369 ARG D CZ  1 
ATOM   16952 N NH1 . ARG D 1 369 ? 162.195 125.683 129.978 1.00 76.06  ? 369 ARG D NH1 1 
ATOM   16953 N NH2 . ARG D 1 369 ? 160.514 127.009 129.539 1.00 69.68  ? 369 ARG D NH2 1 
ATOM   16954 N N   . HIS D 1 370 ? 157.226 124.650 125.295 1.00 78.64  ? 370 HIS D N   1 
ATOM   16955 C CA  . HIS D 1 370 ? 156.329 123.524 125.497 1.00 75.64  ? 370 HIS D CA  1 
ATOM   16956 C C   . HIS D 1 370 ? 155.732 122.988 124.189 1.00 74.83  ? 370 HIS D C   1 
ATOM   16957 O O   . HIS D 1 370 ? 155.460 121.799 124.091 1.00 77.47  ? 370 HIS D O   1 
ATOM   16958 C CB  . HIS D 1 370 ? 155.270 123.911 126.530 1.00 75.32  ? 370 HIS D CB  1 
ATOM   16959 C CG  . HIS D 1 370 ? 154.244 124.918 126.086 1.00 73.61  ? 370 HIS D CG  1 
ATOM   16960 N ND1 . HIS D 1 370 ? 153.097 124.645 125.388 1.00 70.71  ? 370 HIS D ND1 1 
ATOM   16961 C CD2 . HIS D 1 370 ? 154.250 126.257 126.348 1.00 76.62  ? 370 HIS D CD2 1 
ATOM   16962 C CE1 . HIS D 1 370 ? 152.419 125.788 125.236 1.00 75.52  ? 370 HIS D CE1 1 
ATOM   16963 N NE2 . HIS D 1 370 ? 153.086 126.805 125.801 1.00 80.09  ? 370 HIS D NE2 1 
ATOM   16964 N N   . ARG D 1 371 ? 155.605 123.820 123.147 1.00 80.75  ? 371 ARG D N   1 
ATOM   16965 C CA  . ARG D 1 371 ? 155.179 123.406 121.799 1.00 76.94  ? 371 ARG D CA  1 
ATOM   16966 C C   . ARG D 1 371 ? 156.291 122.712 121.019 1.00 73.77  ? 371 ARG D C   1 
ATOM   16967 O O   . ARG D 1 371 ? 156.004 121.897 120.158 1.00 75.01  ? 371 ARG D O   1 
ATOM   16968 C CB  . ARG D 1 371 ? 154.678 124.610 120.994 1.00 76.30  ? 371 ARG D CB  1 
ATOM   16969 C CG  . ARG D 1 371 ? 153.358 125.191 121.514 1.00 75.76  ? 371 ARG D CG  1 
ATOM   16970 C CD  . ARG D 1 371 ? 152.846 126.347 120.650 1.00 77.90  ? 371 ARG D CD  1 
ATOM   16971 N NE  . ARG D 1 371 ? 152.539 125.914 119.272 1.00 86.24  ? 371 ARG D NE  1 
ATOM   16972 C CZ  . ARG D 1 371 ? 152.465 126.672 118.192 1.00 85.33  ? 371 ARG D CZ  1 
ATOM   16973 N NH1 . ARG D 1 371 ? 152.292 126.133 117.026 1.00 79.36  ? 371 ARG D NH1 1 
ATOM   16974 N NH2 . ARG D 1 371 ? 152.568 127.967 118.242 1.00 83.05  ? 371 ARG D NH2 1 
ATOM   16975 N N   . MET D 1 372 ? 157.556 123.005 121.319 1.00 67.83  ? 372 MET D N   1 
ATOM   16976 C CA  . MET D 1 372 ? 158.713 122.382 120.667 1.00 58.64  ? 372 MET D CA  1 
ATOM   16977 C C   . MET D 1 372 ? 159.014 120.962 121.154 1.00 70.24  ? 372 MET D C   1 
ATOM   16978 O O   . MET D 1 372 ? 159.384 120.120 120.346 1.00 77.58  ? 372 MET D O   1 
ATOM   16979 C CB  . MET D 1 372 ? 159.953 123.270 120.818 1.00 65.77  ? 372 MET D CB  1 
ATOM   16980 C CG  . MET D 1 372 ? 159.771 124.594 120.076 1.00 71.31  ? 372 MET D CG  1 
ATOM   16981 S SD  . MET D 1 372 ? 161.274 125.566 119.876 1.00 70.26  ? 372 MET D SD  1 
ATOM   16982 C CE  . MET D 1 372 ? 161.498 126.165 121.555 1.00 73.42  ? 372 MET D CE  1 
ATOM   16983 N N   . VAL D 1 373 ? 158.824 120.632 122.427 1.00 74.15  ? 373 VAL D N   1 
ATOM   16984 C CA  . VAL D 1 373 ? 159.097 119.265 122.910 1.00 69.04  ? 373 VAL D CA  1 
ATOM   16985 C C   . VAL D 1 373 ? 158.062 118.232 122.467 1.00 68.68  ? 373 VAL D C   1 
ATOM   16986 O O   . VAL D 1 373 ? 158.318 117.038 122.558 1.00 73.89  ? 373 VAL D O   1 
ATOM   16987 C CB  . VAL D 1 373 ? 159.250 119.221 124.431 1.00 64.21  ? 373 VAL D CB  1 
ATOM   16988 C CG1 . VAL D 1 373 ? 160.449 120.047 124.881 1.00 68.05  ? 373 VAL D CG1 1 
ATOM   16989 C CG2 . VAL D 1 373 ? 158.002 119.710 125.147 1.00 68.50  ? 373 VAL D CG2 1 
ATOM   16990 N N   . VAL D 1 374 ? 156.888 118.660 121.996 1.00 68.31  ? 374 VAL D N   1 
ATOM   16991 C CA  . VAL D 1 374 ? 155.821 117.765 121.516 1.00 67.77  ? 374 VAL D CA  1 
ATOM   16992 C C   . VAL D 1 374 ? 155.860 117.534 120.000 1.00 74.31  ? 374 VAL D C   1 
ATOM   16993 O O   . VAL D 1 374 ? 155.004 116.834 119.465 1.00 78.48  ? 374 VAL D O   1 
ATOM   16994 C CB  . VAL D 1 374 ? 154.430 118.198 122.005 1.00 72.60  ? 374 VAL D CB  1 
ATOM   16995 C CG1 . VAL D 1 374 ? 154.374 118.212 123.530 1.00 76.06  ? 374 VAL D CG1 1 
ATOM   16996 C CG2 . VAL D 1 374 ? 153.986 119.563 121.491 1.00 69.89  ? 374 VAL D CG2 1 
ATOM   16997 N N   . LEU D 1 375 ? 156.870 118.021 119.267 1.00 69.84  ? 375 LEU D N   1 
ATOM   16998 C CA  . LEU D 1 375 ? 157.117 117.664 117.857 1.00 63.45  ? 375 LEU D CA  1 
ATOM   16999 C C   . LEU D 1 375 ? 157.797 116.295 117.705 1.00 67.28  ? 375 LEU D C   1 
ATOM   17000 O O   . LEU D 1 375 ? 158.588 115.917 118.555 1.00 78.47  ? 375 LEU D O   1 
ATOM   17001 C CB  . LEU D 1 375 ? 158.037 118.706 117.206 1.00 65.37  ? 375 LEU D CB  1 
ATOM   17002 C CG  . LEU D 1 375 ? 157.533 120.152 117.212 1.00 67.35  ? 375 LEU D CG  1 
ATOM   17003 C CD1 . LEU D 1 375 ? 158.526 121.013 116.447 1.00 65.25  ? 375 LEU D CD1 1 
ATOM   17004 C CD2 . LEU D 1 375 ? 156.168 120.269 116.559 1.00 66.72  ? 375 LEU D CD2 1 
ATOM   17005 N N   . GLU D 1 376 ? 157.588 115.564 116.610 1.00 70.56  ? 376 GLU D N   1 
ATOM   17006 C CA  . GLU D 1 376 ? 158.454 114.417 116.276 1.00 76.05  ? 376 GLU D CA  1 
ATOM   17007 C C   . GLU D 1 376 ? 159.774 114.875 115.627 1.00 74.54  ? 376 GLU D C   1 
ATOM   17008 O O   . GLU D 1 376 ? 159.766 115.849 114.879 1.00 76.41  ? 376 GLU D O   1 
ATOM   17009 C CB  . GLU D 1 376 ? 157.732 113.412 115.369 1.00 75.37  ? 376 GLU D CB  1 
ATOM   17010 C CG  . GLU D 1 376 ? 156.444 112.817 115.957 1.00 77.88  ? 376 GLU D CG  1 
ATOM   17011 C CD  . GLU D 1 376 ? 156.571 112.181 117.355 1.00 84.38  ? 376 GLU D CD  1 
ATOM   17012 O OE1 . GLU D 1 376 ? 157.684 111.802 117.775 1.00 90.91  ? 376 GLU D OE1 1 
ATOM   17013 O OE2 . GLU D 1 376 ? 155.526 112.069 118.036 1.00 82.97  ? 376 GLU D OE2 1 
ATOM   17014 N N   . PRO D 1 377 ? 160.911 114.198 115.875 1.00 60.92  ? 377 PRO D N   1 
ATOM   17015 C CA  . PRO D 1 377 ? 161.078 113.005 116.705 1.00 57.86  ? 377 PRO D CA  1 
ATOM   17016 C C   . PRO D 1 377 ? 161.146 113.274 118.217 1.00 67.26  ? 377 PRO D C   1 
ATOM   17017 O O   . PRO D 1 377 ? 161.176 112.321 118.984 1.00 79.49  ? 377 PRO D O   1 
ATOM   17018 C CB  . PRO D 1 377 ? 162.397 112.402 116.227 1.00 65.46  ? 377 PRO D CB  1 
ATOM   17019 C CG  . PRO D 1 377 ? 163.226 113.630 115.872 1.00 60.83  ? 377 PRO D CG  1 
ATOM   17020 C CD  . PRO D 1 377 ? 162.182 114.563 115.272 1.00 58.30  ? 377 PRO D CD  1 
ATOM   17021 N N   . LEU D 1 378 ? 161.202 114.531 118.671 1.00 70.54  ? 378 LEU D N   1 
ATOM   17022 C CA  . LEU D 1 378 ? 161.453 114.919 120.066 1.00 62.55  ? 378 LEU D CA  1 
ATOM   17023 C C   . LEU D 1 378 ? 160.469 114.299 121.061 1.00 66.86  ? 378 LEU D C   1 
ATOM   17024 O O   . LEU D 1 378 ? 160.888 113.818 122.105 1.00 75.14  ? 378 LEU D O   1 
ATOM   17025 C CB  . LEU D 1 378 ? 161.426 116.454 120.177 1.00 61.71  ? 378 LEU D CB  1 
ATOM   17026 C CG  . LEU D 1 378 ? 162.743 117.163 119.859 1.00 60.67  ? 378 LEU D CG  1 
ATOM   17027 C CD1 . LEU D 1 378 ? 163.343 116.793 118.532 1.00 63.63  ? 378 LEU D CD1 1 
ATOM   17028 C CD2 . LEU D 1 378 ? 162.526 118.656 119.875 1.00 65.71  ? 378 LEU D CD2 1 
ATOM   17029 N N   . ASN D 1 379 ? 159.185 114.253 120.737 1.00 66.18  ? 379 ASN D N   1 
ATOM   17030 C CA  . ASN D 1 379 ? 158.130 113.627 121.531 1.00 69.12  ? 379 ASN D CA  1 
ATOM   17031 C C   . ASN D 1 379 ? 158.397 112.137 121.805 1.00 72.00  ? 379 ASN D C   1 
ATOM   17032 O O   . ASN D 1 379 ? 158.508 111.755 122.973 1.00 77.25  ? 379 ASN D O   1 
ATOM   17033 C CB  . ASN D 1 379 ? 156.796 113.863 120.824 1.00 65.91  ? 379 ASN D CB  1 
ATOM   17034 C CG  . ASN D 1 379 ? 155.635 113.162 121.493 1.00 74.84  ? 379 ASN D CG  1 
ATOM   17035 O OD1 . ASN D 1 379 ? 155.443 113.233 122.701 1.00 78.41  ? 379 ASN D OD1 1 
ATOM   17036 N ND2 . ASN D 1 379 ? 154.845 112.445 120.734 1.00 74.98  ? 379 ASN D ND2 1 
ATOM   17037 N N   . LYS D 1 380 ? 158.569 111.297 120.773 1.00 69.47  ? 380 LYS D N   1 
ATOM   17038 C CA  . LYS D 1 380 ? 158.917 109.881 120.973 1.00 62.26  ? 380 LYS D CA  1 
ATOM   17039 C C   . LYS D 1 380 ? 160.313 109.705 121.580 1.00 66.16  ? 380 LYS D C   1 
ATOM   17040 O O   . LYS D 1 380 ? 160.494 108.834 122.417 1.00 76.22  ? 380 LYS D O   1 
ATOM   17041 C CB  . LYS D 1 380 ? 158.754 109.088 119.666 1.00 61.53  ? 380 LYS D CB  1 
ATOM   17042 C CG  . LYS D 1 380 ? 158.833 107.574 119.933 1.00 73.27  ? 380 LYS D CG  1 
ATOM   17043 C CD  . LYS D 1 380 ? 158.985 106.702 118.681 1.00 80.11  ? 380 LYS D CD  1 
ATOM   17044 C CE  . LYS D 1 380 ? 159.312 105.273 119.133 1.00 74.20  ? 380 LYS D CE  1 
ATOM   17045 N NZ  . LYS D 1 380 ? 159.511 104.338 118.001 1.00 63.73  ? 380 LYS D NZ  1 
ATOM   17046 N N   . LEU D 1 381 ? 161.289 110.538 121.235 1.00 61.22  ? 381 LEU D N   1 
ATOM   17047 C CA  . LEU D 1 381 ? 162.640 110.493 121.798 1.00 57.16  ? 381 LEU D CA  1 
ATOM   17048 C C   . LEU D 1 381 ? 162.681 110.808 123.306 1.00 65.36  ? 381 LEU D C   1 
ATOM   17049 O O   . LEU D 1 381 ? 163.407 110.160 124.053 1.00 72.56  ? 381 LEU D O   1 
ATOM   17050 C CB  . LEU D 1 381 ? 163.493 111.470 120.981 1.00 58.97  ? 381 LEU D CB  1 
ATOM   17051 C CG  . LEU D 1 381 ? 164.988 111.508 121.314 1.00 63.58  ? 381 LEU D CG  1 
ATOM   17052 C CD1 . LEU D 1 381 ? 165.649 110.157 121.072 1.00 63.77  ? 381 LEU D CD1 1 
ATOM   17053 C CD2 . LEU D 1 381 ? 165.654 112.530 120.405 1.00 64.14  ? 381 LEU D CD2 1 
ATOM   17054 N N   . LEU D 1 382 ? 161.885 111.766 123.786 1.00 62.74  ? 382 LEU D N   1 
ATOM   17055 C CA  . LEU D 1 382 ? 161.747 112.087 125.196 1.00 59.46  ? 382 LEU D CA  1 
ATOM   17056 C C   . LEU D 1 382 ? 160.876 111.068 125.930 1.00 63.14  ? 382 LEU D C   1 
ATOM   17057 O O   . LEU D 1 382 ? 161.136 110.804 127.096 1.00 71.67  ? 382 LEU D O   1 
ATOM   17058 C CB  . LEU D 1 382 ? 161.190 113.509 125.326 1.00 60.89  ? 382 LEU D CB  1 
ATOM   17059 C CG  . LEU D 1 382 ? 162.191 114.597 124.912 1.00 57.14  ? 382 LEU D CG  1 
ATOM   17060 C CD1 . LEU D 1 382 ? 161.449 115.910 124.718 1.00 55.24  ? 382 LEU D CD1 1 
ATOM   17061 C CD2 . LEU D 1 382 ? 163.280 114.765 125.965 1.00 66.99  ? 382 LEU D CD2 1 
ATOM   17062 N N   . GLN D 1 383 ? 159.893 110.447 125.276 1.00 66.78  ? 383 GLN D N   1 
ATOM   17063 C CA  . GLN D 1 383 ? 159.161 109.322 125.859 1.00 62.79  ? 383 GLN D CA  1 
ATOM   17064 C C   . GLN D 1 383 ? 160.062 108.098 126.050 1.00 70.93  ? 383 GLN D C   1 
ATOM   17065 O O   . GLN D 1 383 ? 160.045 107.480 127.103 1.00 80.68  ? 383 GLN D O   1 
ATOM   17066 C CB  . GLN D 1 383 ? 157.947 108.981 124.991 1.00 66.02  ? 383 GLN D CB  1 
ATOM   17067 C CG  . GLN D 1 383 ? 157.032 107.939 125.644 1.00 70.75  ? 383 GLN D CG  1 
ATOM   17068 C CD  . GLN D 1 383 ? 156.358 108.432 126.924 1.00 79.15  ? 383 GLN D CD  1 
ATOM   17069 O OE1 . GLN D 1 383 ? 155.777 109.510 126.978 1.00 84.66  ? 383 GLN D OE1 1 
ATOM   17070 N NE2 . GLN D 1 383 ? 156.384 107.681 127.994 1.00 73.97  ? 383 GLN D NE2 1 
ATOM   17071 N N   . GLU D 1 384 ? 160.883 107.761 125.059 1.00 69.62  ? 384 GLU D N   1 
ATOM   17072 C CA  . GLU D 1 384 ? 161.878 106.693 125.137 1.00 63.34  ? 384 GLU D CA  1 
ATOM   17073 C C   . GLU D 1 384 ? 162.888 106.919 126.266 1.00 71.67  ? 384 GLU D C   1 
ATOM   17074 O O   . GLU D 1 384 ? 163.172 106.002 127.028 1.00 75.12  ? 384 GLU D O   1 
ATOM   17075 C CB  . GLU D 1 384 ? 162.609 106.609 123.792 1.00 67.36  ? 384 GLU D CB  1 
ATOM   17076 C CG  . GLU D 1 384 ? 161.819 105.863 122.708 1.00 78.98  ? 384 GLU D CG  1 
ATOM   17077 C CD  . GLU D 1 384 ? 162.263 104.427 122.407 1.00 84.22  ? 384 GLU D CD  1 
ATOM   17078 O OE1 . GLU D 1 384 ? 163.319 103.961 122.891 1.00 86.08  ? 384 GLU D OE1 1 
ATOM   17079 O OE2 . GLU D 1 384 ? 161.548 103.754 121.652 1.00 77.41  ? 384 GLU D OE2 1 
ATOM   17080 N N   . LYS D 1 385 ? 163.400 108.143 126.430 1.00 77.50  ? 385 LYS D N   1 
ATOM   17081 C CA  . LYS D 1 385 ? 164.267 108.505 127.559 1.00 65.94  ? 385 LYS D CA  1 
ATOM   17082 C C   . LYS D 1 385 ? 163.527 108.442 128.894 1.00 65.41  ? 385 LYS D C   1 
ATOM   17083 O O   . LYS D 1 385 ? 164.063 107.903 129.854 1.00 72.13  ? 385 LYS D O   1 
ATOM   17084 C CB  . LYS D 1 385 ? 164.849 109.903 127.338 1.00 67.27  ? 385 LYS D CB  1 
ATOM   17085 C CG  . LYS D 1 385 ? 165.917 109.951 126.244 1.00 69.01  ? 385 LYS D CG  1 
ATOM   17086 C CD  . LYS D 1 385 ? 166.347 111.393 125.955 1.00 69.28  ? 385 LYS D CD  1 
ATOM   17087 C CE  . LYS D 1 385 ? 167.345 111.487 124.803 1.00 76.61  ? 385 LYS D CE  1 
ATOM   17088 N NZ  . LYS D 1 385 ? 168.606 110.785 125.080 1.00 66.90  ? 385 LYS D NZ  1 
ATOM   17089 N N   . TRP D 1 386 ? 162.299 108.948 128.977 1.00 65.35  ? 386 TRP D N   1 
ATOM   17090 C CA  . TRP D 1 386 ? 161.476 108.908 130.182 1.00 65.50  ? 386 TRP D CA  1 
ATOM   17091 C C   . TRP D 1 386 ? 161.213 107.478 130.643 1.00 66.38  ? 386 TRP D C   1 
ATOM   17092 O O   . TRP D 1 386 ? 161.444 107.155 131.797 1.00 75.97  ? 386 TRP D O   1 
ATOM   17093 C CB  . TRP D 1 386 ? 160.163 109.659 129.943 1.00 63.72  ? 386 TRP D CB  1 
ATOM   17094 C CG  . TRP D 1 386 ? 159.197 109.575 131.075 1.00 68.29  ? 386 TRP D CG  1 
ATOM   17095 C CD1 . TRP D 1 386 ? 158.104 108.784 131.120 1.00 69.23  ? 386 TRP D CD1 1 
ATOM   17096 C CD2 . TRP D 1 386 ? 159.292 110.204 132.383 1.00 73.63  ? 386 TRP D CD2 1 
ATOM   17097 N NE1 . TRP D 1 386 ? 157.511 108.890 132.362 1.00 70.90  ? 386 TRP D NE1 1 
ATOM   17098 C CE2 . TRP D 1 386 ? 158.219 109.733 133.188 1.00 73.13  ? 386 TRP D CE2 1 
ATOM   17099 C CE3 . TRP D 1 386 ? 160.207 111.087 132.986 1.00 70.63  ? 386 TRP D CE3 1 
ATOM   17100 C CZ2 . TRP D 1 386 ? 158.066 110.125 134.520 1.00 69.39  ? 386 TRP D CZ2 1 
ATOM   17101 C CZ3 . TRP D 1 386 ? 160.056 111.493 134.320 1.00 64.50  ? 386 TRP D CZ3 1 
ATOM   17102 C CH2 . TRP D 1 386 ? 158.988 111.018 135.085 1.00 68.30  ? 386 TRP D CH2 1 
ATOM   17103 N N   . ASP D 1 387 ? 160.835 106.582 129.743 1.00 66.34  ? 387 ASP D N   1 
ATOM   17104 C CA  . ASP D 1 387 ? 160.618 105.162 130.033 1.00 66.65  ? 387 ASP D CA  1 
ATOM   17105 C C   . ASP D 1 387 ? 161.878 104.464 130.578 1.00 69.13  ? 387 ASP D C   1 
ATOM   17106 O O   . ASP D 1 387 ? 161.777 103.598 131.442 1.00 75.06  ? 387 ASP D O   1 
ATOM   17107 C CB  . ASP D 1 387 ? 160.135 104.436 128.770 1.00 74.51  ? 387 ASP D CB  1 
ATOM   17108 C CG  . ASP D 1 387 ? 158.764 104.868 128.236 1.00 77.05  ? 387 ASP D CG  1 
ATOM   17109 O OD1 . ASP D 1 387 ? 158.008 105.574 128.938 1.00 71.85  ? 387 ASP D OD1 1 
ATOM   17110 O OD2 . ASP D 1 387 ? 158.405 104.426 127.123 1.00 75.68  ? 387 ASP D OD2 1 
ATOM   17111 N N   . ARG D 1 388 ? 163.074 104.835 130.106 1.00 80.32  ? 388 ARG D N   1 
ATOM   17112 C CA  . ARG D 1 388 ? 164.351 104.347 130.652 1.00 78.76  ? 388 ARG D CA  1 
ATOM   17113 C C   . ARG D 1 388 ? 164.705 104.930 132.021 1.00 85.00  ? 388 ARG D C   1 
ATOM   17114 O O   . ARG D 1 388 ? 165.599 104.355 132.671 1.00 83.99  ? 388 ARG D O   1 
ATOM   17115 C CB  . ARG D 1 388 ? 165.490 104.582 129.643 1.00 78.62  ? 388 ARG D CB  1 
ATOM   17116 C CG  . ARG D 1 388 ? 165.378 103.620 128.454 1.00 85.28  ? 388 ARG D CG  1 
ATOM   17117 C CD  . ARG D 1 388 ? 166.612 103.620 127.531 1.00 84.40  ? 388 ARG D CD  1 
ATOM   17118 N NE  . ARG D 1 388 ? 166.656 104.933 126.905 1.00 90.38  ? 388 ARG D NE  1 
ATOM   17119 C CZ  . ARG D 1 388 ? 165.846 105.318 125.925 1.00 95.63  ? 388 ARG D CZ  1 
ATOM   17120 N NH1 . ARG D 1 388 ? 165.943 106.538 125.425 1.00 90.77  ? 388 ARG D NH1 1 
ATOM   17121 N NH2 . ARG D 1 388 ? 164.934 104.487 125.455 1.00 90.09  ? 388 ARG D NH2 1 
ATOM   17122 N N   . LEU D 1 389 ? 164.061 106.015 132.454 1.00 78.44  ? 389 LEU D N   1 
ATOM   17123 C CA  . LEU D 1 389 ? 164.412 106.778 133.658 1.00 66.38  ? 389 LEU D CA  1 
ATOM   17124 C C   . LEU D 1 389 ? 163.284 106.900 134.692 1.00 70.34  ? 389 LEU D C   1 
ATOM   17125 O O   . LEU D 1 389 ? 163.552 107.324 135.808 1.00 81.19  ? 389 LEU D O   1 
ATOM   17126 C CB  . LEU D 1 389 ? 164.928 108.160 133.238 1.00 68.35  ? 389 LEU D CB  1 
ATOM   17127 C CG  . LEU D 1 389 ? 166.265 108.147 132.480 1.00 71.97  ? 389 LEU D CG  1 
ATOM   17128 C CD1 . LEU D 1 389 ? 166.511 109.510 131.851 1.00 71.14  ? 389 LEU D CD1 1 
ATOM   17129 C CD2 . LEU D 1 389 ? 167.436 107.826 133.404 1.00 66.83  ? 389 LEU D CD2 1 
ATOM   17130 N N   . VAL D 1 390 ? 162.049 106.492 134.401 1.00 71.13  ? 390 VAL D N   1 
ATOM   17131 C CA  . VAL D 1 390 ? 160.897 106.589 135.309 1.00 71.05  ? 390 VAL D CA  1 
ATOM   17132 C C   . VAL D 1 390 ? 161.121 105.845 136.635 1.00 76.47  ? 390 VAL D C   1 
ATOM   17133 O O   . VAL D 1 390 ? 160.737 106.324 137.696 1.00 78.84  ? 390 VAL D O   1 
ATOM   17134 C CB  . VAL D 1 390 ? 159.623 106.161 134.561 1.00 63.94  ? 390 VAL D CB  1 
ATOM   17135 C CG1 . VAL D 1 390 ? 159.597 104.679 134.192 1.00 67.98  ? 390 VAL D CG1 1 
ATOM   17136 C CG2 . VAL D 1 390 ? 158.364 106.471 135.360 1.00 69.65  ? 390 VAL D CG2 1 
ATOM   17137 N N   . SER D 1 391 ? 161.852 104.731 136.626 1.00 77.10  ? 391 SER D N   1 
ATOM   17138 C CA  . SER D 1 391 ? 162.270 104.015 137.838 1.00 70.17  ? 391 SER D CA  1 
ATOM   17139 C C   . SER D 1 391 ? 163.326 104.770 138.653 1.00 74.56  ? 391 SER D C   1 
ATOM   17140 O O   . SER D 1 391 ? 163.329 104.667 139.878 1.00 87.90  ? 391 SER D O   1 
ATOM   17141 C CB  . SER D 1 391 ? 162.803 102.635 137.457 1.00 73.69  ? 391 SER D CB  1 
ATOM   17142 O OG  . SER D 1 391 ? 163.913 102.753 136.589 1.00 81.83  ? 391 SER D OG  1 
ATOM   17143 N N   . ARG D 1 392 ? 164.174 105.587 138.021 1.00 74.12  ? 392 ARG D N   1 
ATOM   17144 C CA  . ARG D 1 392 ? 165.112 106.503 138.695 1.00 63.71  ? 392 ARG D CA  1 
ATOM   17145 C C   . ARG D 1 392 ? 164.378 107.708 139.274 1.00 71.05  ? 392 ARG D C   1 
ATOM   17146 O O   . ARG D 1 392 ? 164.655 108.113 140.392 1.00 88.30  ? 392 ARG D O   1 
ATOM   17147 C CB  . ARG D 1 392 ? 166.205 106.937 137.710 1.00 70.73  ? 392 ARG D CB  1 
ATOM   17148 C CG  . ARG D 1 392 ? 167.471 107.400 138.433 1.00 69.16  ? 392 ARG D CG  1 
ATOM   17149 C CD  . ARG D 1 392 ? 168.547 107.799 137.414 1.00 82.01  ? 392 ARG D CD  1 
ATOM   17150 N NE  . ARG D 1 392 ? 169.890 107.830 138.020 1.00 87.69  ? 392 ARG D NE  1 
ATOM   17151 C CZ  . ARG D 1 392 ? 170.710 106.804 138.174 1.00 92.58  ? 392 ARG D CZ  1 
ATOM   17152 N NH1 . ARG D 1 392 ? 171.886 106.965 138.704 1.00 88.09  ? 392 ARG D NH1 1 
ATOM   17153 N NH2 . ARG D 1 392 ? 170.397 105.597 137.807 1.00 88.13  ? 392 ARG D NH2 1 
ATOM   17154 N N   . PHE D 1 393 ? 163.380 108.229 138.571 1.00 62.33  ? 393 PHE D N   1 
ATOM   17155 C CA  . PHE D 1 393 ? 162.510 109.295 139.053 1.00 55.11  ? 393 PHE D CA  1 
ATOM   17156 C C   . PHE D 1 393 ? 161.768 108.885 140.325 1.00 65.53  ? 393 PHE D C   1 
ATOM   17157 O O   . PHE D 1 393 ? 161.792 109.612 141.314 1.00 77.66  ? 393 PHE D O   1 
ATOM   17158 C CB  . PHE D 1 393 ? 161.536 109.697 137.946 1.00 56.92  ? 393 PHE D CB  1 
ATOM   17159 C CG  . PHE D 1 393 ? 160.699 110.902 138.294 1.00 60.48  ? 393 PHE D CG  1 
ATOM   17160 C CD1 . PHE D 1 393 ? 161.221 112.193 138.100 1.00 67.83  ? 393 PHE D CD1 1 
ATOM   17161 C CD2 . PHE D 1 393 ? 159.406 110.746 138.819 1.00 57.70  ? 393 PHE D CD2 1 
ATOM   17162 C CE1 . PHE D 1 393 ? 160.446 113.317 138.414 1.00 62.48  ? 393 PHE D CE1 1 
ATOM   17163 C CE2 . PHE D 1 393 ? 158.636 111.872 139.136 1.00 62.25  ? 393 PHE D CE2 1 
ATOM   17164 C CZ  . PHE D 1 393 ? 159.152 113.157 138.919 1.00 58.32  ? 393 PHE D CZ  1 
ATOM   17165 N N   . PHE D 1 394 ? 161.156 107.697 140.349 1.00 71.25  ? 394 PHE D N   1 
ATOM   17166 C CA  . PHE D 1 394 ? 160.442 107.226 141.532 1.00 66.07  ? 394 PHE D CA  1 
ATOM   17167 C C   . PHE D 1 394 ? 161.345 106.689 142.650 1.00 62.38  ? 394 PHE D C   1 
ATOM   17168 O O   . PHE D 1 394 ? 160.981 106.797 143.814 1.00 77.72  ? 394 PHE D O   1 
ATOM   17169 C CB  . PHE D 1 394 ? 159.313 106.285 141.122 1.00 63.62  ? 394 PHE D CB  1 
ATOM   17170 C CG  . PHE D 1 394 ? 158.194 107.027 140.411 1.00 74.04  ? 394 PHE D CG  1 
ATOM   17171 C CD1 . PHE D 1 394 ? 157.488 108.036 141.088 1.00 72.56  ? 394 PHE D CD1 1 
ATOM   17172 C CD2 . PHE D 1 394 ? 157.873 106.743 139.074 1.00 66.45  ? 394 PHE D CD2 1 
ATOM   17173 C CE1 . PHE D 1 394 ? 156.482 108.766 140.439 1.00 69.15  ? 394 PHE D CE1 1 
ATOM   17174 C CE2 . PHE D 1 394 ? 156.856 107.462 138.426 1.00 65.36  ? 394 PHE D CE2 1 
ATOM   17175 C CZ  . PHE D 1 394 ? 156.161 108.468 139.108 1.00 70.08  ? 394 PHE D CZ  1 
ATOM   17176 N N   . PHE D 1 395 ? 162.549 106.208 142.353 1.00 60.95  ? 395 PHE D N   1 
ATOM   17177 C CA  . PHE D 1 395 ? 163.573 105.985 143.370 1.00 62.88  ? 395 PHE D CA  1 
ATOM   17178 C C   . PHE D 1 395 ? 163.983 107.297 144.049 1.00 69.35  ? 395 PHE D C   1 
ATOM   17179 O O   . PHE D 1 395 ? 163.983 107.385 145.275 1.00 81.93  ? 395 PHE D O   1 
ATOM   17180 C CB  . PHE D 1 395 ? 164.767 105.282 142.723 1.00 65.10  ? 395 PHE D CB  1 
ATOM   17181 C CG  . PHE D 1 395 ? 165.943 105.080 143.652 1.00 69.40  ? 395 PHE D CG  1 
ATOM   17182 C CD1 . PHE D 1 395 ? 165.873 104.124 144.677 1.00 75.73  ? 395 PHE D CD1 1 
ATOM   17183 C CD2 . PHE D 1 395 ? 167.108 105.844 143.488 1.00 69.17  ? 395 PHE D CD2 1 
ATOM   17184 C CE1 . PHE D 1 395 ? 166.965 103.934 145.537 1.00 73.63  ? 395 PHE D CE1 1 
ATOM   17185 C CE2 . PHE D 1 395 ? 168.204 105.644 144.339 1.00 74.04  ? 395 PHE D CE2 1 
ATOM   17186 C CZ  . PHE D 1 395 ? 168.134 104.689 145.363 1.00 74.80  ? 395 PHE D CZ  1 
ATOM   17187 N N   . ASN D 1 396 ? 164.247 108.353 143.281 1.00 69.09  ? 396 ASN D N   1 
ATOM   17188 C CA  . ASN D 1 396 ? 164.572 109.675 143.806 1.00 64.78  ? 396 ASN D CA  1 
ATOM   17189 C C   . ASN D 1 396 ? 163.449 110.260 144.685 1.00 70.02  ? 396 ASN D C   1 
ATOM   17190 O O   . ASN D 1 396 ? 163.726 110.847 145.728 1.00 77.50  ? 396 ASN D O   1 
ATOM   17191 C CB  . ASN D 1 396 ? 164.882 110.607 142.626 1.00 69.06  ? 396 ASN D CB  1 
ATOM   17192 C CG  . ASN D 1 396 ? 166.187 110.322 141.900 1.00 72.77  ? 396 ASN D CG  1 
ATOM   17193 O OD1 . ASN D 1 396 ? 166.948 109.418 142.204 1.00 75.36  ? 396 ASN D OD1 1 
ATOM   17194 N ND2 . ASN D 1 396 ? 166.527 111.140 140.936 1.00 73.51  ? 396 ASN D ND2 1 
ATOM   17195 N N   . PHE D 1 397 ? 162.189 110.048 144.306 1.00 58.12  ? 397 PHE D N   1 
ATOM   17196 C CA  . PHE D 1 397 ? 160.997 110.352 145.099 1.00 58.37  ? 397 PHE D CA  1 
ATOM   17197 C C   . PHE D 1 397 ? 160.907 109.548 146.400 1.00 65.29  ? 397 PHE D C   1 
ATOM   17198 O O   . PHE D 1 397 ? 160.631 110.126 147.445 1.00 73.03  ? 397 PHE D O   1 
ATOM   17199 C CB  . PHE D 1 397 ? 159.760 110.091 144.244 1.00 55.63  ? 397 PHE D CB  1 
ATOM   17200 C CG  . PHE D 1 397 ? 158.429 110.159 144.968 1.00 64.70  ? 397 PHE D CG  1 
ATOM   17201 C CD1 . PHE D 1 397 ? 158.039 111.330 145.636 1.00 64.79  ? 397 PHE D CD1 1 
ATOM   17202 C CD2 . PHE D 1 397 ? 157.569 109.048 144.963 1.00 69.09  ? 397 PHE D CD2 1 
ATOM   17203 C CE1 . PHE D 1 397 ? 156.785 111.409 146.252 1.00 56.18  ? 397 PHE D CE1 1 
ATOM   17204 C CE2 . PHE D 1 397 ? 156.320 109.119 145.597 1.00 67.92  ? 397 PHE D CE2 1 
ATOM   17205 C CZ  . PHE D 1 397 ? 155.925 110.303 146.232 1.00 65.24  ? 397 PHE D CZ  1 
ATOM   17206 N N   . ALA D 1 398 ? 161.161 108.238 146.373 1.00 69.65  ? 398 ALA D N   1 
ATOM   17207 C CA  . ALA D 1 398 ? 161.143 107.384 147.555 1.00 56.41  ? 398 ALA D CA  1 
ATOM   17208 C C   . ALA D 1 398 ? 162.255 107.733 148.557 1.00 62.99  ? 398 ALA D C   1 
ATOM   17209 O O   . ALA D 1 398 ? 161.995 107.785 149.754 1.00 83.39  ? 398 ALA D O   1 
ATOM   17210 C CB  . ALA D 1 398 ? 161.225 105.930 147.104 1.00 55.94  ? 398 ALA D CB  1 
ATOM   17211 N N   . CYS D 1 399 ? 163.469 108.056 148.109 1.00 59.27  ? 399 CYS D N   1 
ATOM   17212 C CA  . CYS D 1 399 ? 164.508 108.596 148.990 1.00 67.71  ? 399 CYS D CA  1 
ATOM   17213 C C   . CYS D 1 399 ? 164.074 109.903 149.661 1.00 66.36  ? 399 CYS D C   1 
ATOM   17214 O O   . CYS D 1 399 ? 164.311 110.088 150.851 1.00 76.94  ? 399 CYS D O   1 
ATOM   17215 C CB  . CYS D 1 399 ? 165.776 108.848 148.182 1.00 71.04  ? 399 CYS D CB  1 
ATOM   17216 S SG  . CYS D 1 399 ? 166.541 107.295 147.688 1.00 72.59  ? 399 CYS D SG  1 
ATOM   17217 N N   . TYR D 1 400 ? 163.416 110.781 148.912 1.00 54.62  ? 400 TYR D N   1 
ATOM   17218 C CA  . TYR D 1 400 ? 162.947 112.048 149.438 1.00 51.92  ? 400 TYR D CA  1 
ATOM   17219 C C   . TYR D 1 400 ? 161.749 111.873 150.384 1.00 65.12  ? 400 TYR D C   1 
ATOM   17220 O O   . TYR D 1 400 ? 161.689 112.543 151.405 1.00 80.26  ? 400 TYR D O   1 
ATOM   17221 C CB  . TYR D 1 400 ? 162.667 112.986 148.275 1.00 57.47  ? 400 TYR D CB  1 
ATOM   17222 C CG  . TYR D 1 400 ? 162.443 114.406 148.729 1.00 62.86  ? 400 TYR D CG  1 
ATOM   17223 C CD1 . TYR D 1 400 ? 163.534 115.232 149.039 1.00 59.80  ? 400 TYR D CD1 1 
ATOM   17224 C CD2 . TYR D 1 400 ? 161.135 114.874 148.895 1.00 57.33  ? 400 TYR D CD2 1 
ATOM   17225 C CE1 . TYR D 1 400 ? 163.306 116.528 149.529 1.00 51.09  ? 400 TYR D CE1 1 
ATOM   17226 C CE2 . TYR D 1 400 ? 160.899 116.166 149.372 1.00 50.80  ? 400 TYR D CE2 1 
ATOM   17227 C CZ  . TYR D 1 400 ? 161.991 116.986 149.698 1.00 53.91  ? 400 TYR D CZ  1 
ATOM   17228 O OH  . TYR D 1 400 ? 161.767 118.204 150.224 1.00 66.93  ? 400 TYR D OH  1 
ATOM   17229 N N   . LEU D 1 401 ? 160.850 110.912 150.152 1.00 55.25  ? 401 LEU D N   1 
ATOM   17230 C CA  . LEU D 1 401 ? 159.831 110.504 151.118 1.00 48.34  ? 401 LEU D CA  1 
ATOM   17231 C C   . LEU D 1 401 ? 160.449 109.993 152.424 1.00 55.61  ? 401 LEU D C   1 
ATOM   17232 O O   . LEU D 1 401 ? 160.016 110.391 153.494 1.00 71.64  ? 401 LEU D O   1 
ATOM   17233 C CB  . LEU D 1 401 ? 158.968 109.372 150.543 1.00 63.08  ? 401 LEU D CB  1 
ATOM   17234 C CG  . LEU D 1 401 ? 157.776 109.777 149.686 1.00 66.12  ? 401 LEU D CG  1 
ATOM   17235 C CD1 . LEU D 1 401 ? 157.148 108.503 149.128 1.00 62.24  ? 401 LEU D CD1 1 
ATOM   17236 C CD2 . LEU D 1 401 ? 156.705 110.486 150.510 1.00 62.20  ? 401 LEU D CD2 1 
ATOM   17237 N N   . VAL D 1 402 ? 161.453 109.121 152.364 1.00 58.65  ? 402 VAL D N   1 
ATOM   17238 C CA  . VAL D 1 402 ? 162.153 108.582 153.541 1.00 62.73  ? 402 VAL D CA  1 
ATOM   17239 C C   . VAL D 1 402 ? 162.886 109.680 154.304 1.00 64.13  ? 402 VAL D C   1 
ATOM   17240 O O   . VAL D 1 402 ? 162.807 109.730 155.524 1.00 74.10  ? 402 VAL D O   1 
ATOM   17241 C CB  . VAL D 1 402 ? 163.104 107.442 153.139 1.00 62.15  ? 402 VAL D CB  1 
ATOM   17242 C CG1 . VAL D 1 402 ? 164.026 107.012 154.281 1.00 69.06  ? 402 VAL D CG1 1 
ATOM   17243 C CG2 . VAL D 1 402 ? 162.291 106.220 152.714 1.00 57.83  ? 402 VAL D CG2 1 
ATOM   17244 N N   . TYR D 1 403 ? 163.560 110.594 153.605 1.00 64.93  ? 403 TYR D N   1 
ATOM   17245 C CA  . TYR D 1 403 ? 164.153 111.790 154.195 1.00 56.12  ? 403 TYR D CA  1 
ATOM   17246 C C   . TYR D 1 403 ? 163.088 112.668 154.857 1.00 61.37  ? 403 TYR D C   1 
ATOM   17247 O O   . TYR D 1 403 ? 163.266 113.046 156.007 1.00 79.53  ? 403 TYR D O   1 
ATOM   17248 C CB  . TYR D 1 403 ? 164.945 112.539 153.118 1.00 67.58  ? 403 TYR D CB  1 
ATOM   17249 C CG  . TYR D 1 403 ? 165.360 113.967 153.430 1.00 70.42  ? 403 TYR D CG  1 
ATOM   17250 C CD1 . TYR D 1 403 ? 166.415 114.238 154.323 1.00 61.54  ? 403 TYR D CD1 1 
ATOM   17251 C CD2 . TYR D 1 403 ? 164.718 115.030 152.771 1.00 72.54  ? 403 TYR D CD2 1 
ATOM   17252 C CE1 . TYR D 1 403 ? 166.830 115.567 154.543 1.00 58.00  ? 403 TYR D CE1 1 
ATOM   17253 C CE2 . TYR D 1 403 ? 165.127 116.355 152.988 1.00 66.42  ? 403 TYR D CE2 1 
ATOM   17254 C CZ  . TYR D 1 403 ? 166.194 116.625 153.865 1.00 63.57  ? 403 TYR D CZ  1 
ATOM   17255 O OH  . TYR D 1 403 ? 166.621 117.900 154.036 1.00 74.72  ? 403 TYR D OH  1 
ATOM   17256 N N   . MET D 1 404 ? 161.948 112.926 154.212 1.00 55.75  ? 404 MET D N   1 
ATOM   17257 C CA  . MET D 1 404 ? 160.858 113.704 154.811 1.00 65.40  ? 404 MET D CA  1 
ATOM   17258 C C   . MET D 1 404 ? 160.094 112.987 155.932 1.00 70.48  ? 404 MET D C   1 
ATOM   17259 O O   . MET D 1 404 ? 159.607 113.646 156.849 1.00 78.00  ? 404 MET D O   1 
ATOM   17260 C CB  . MET D 1 404 ? 159.895 114.209 153.730 1.00 54.05  ? 404 MET D CB  1 
ATOM   17261 C CG  . MET D 1 404 ? 160.489 115.354 152.908 1.00 61.50  ? 404 MET D CG  1 
ATOM   17262 S SD  . MET D 1 404 ? 161.228 116.735 153.831 1.00 63.28  ? 404 MET D SD  1 
ATOM   17263 C CE  . MET D 1 404 ? 159.906 117.154 154.987 1.00 69.76  ? 404 MET D CE  1 
ATOM   17264 N N   . PHE D 1 405 ? 160.033 111.660 155.937 1.00 66.03  ? 405 PHE D N   1 
ATOM   17265 C CA  . PHE D 1 405 ? 159.540 110.877 157.068 1.00 65.96  ? 405 PHE D CA  1 
ATOM   17266 C C   . PHE D 1 405 ? 160.451 111.049 158.291 1.00 68.62  ? 405 PHE D C   1 
ATOM   17267 O O   . PHE D 1 405 ? 159.980 111.470 159.344 1.00 73.67  ? 405 PHE D O   1 
ATOM   17268 C CB  . PHE D 1 405 ? 159.407 109.411 156.644 1.00 62.93  ? 405 PHE D CB  1 
ATOM   17269 C CG  . PHE D 1 405 ? 158.993 108.470 157.754 1.00 77.51  ? 405 PHE D CG  1 
ATOM   17270 C CD1 . PHE D 1 405 ? 157.635 108.279 158.053 1.00 78.09  ? 405 PHE D CD1 1 
ATOM   17271 C CD2 . PHE D 1 405 ? 159.972 107.792 158.501 1.00 80.06  ? 405 PHE D CD2 1 
ATOM   17272 C CE1 . PHE D 1 405 ? 157.254 107.427 159.103 1.00 77.43  ? 405 PHE D CE1 1 
ATOM   17273 C CE2 . PHE D 1 405 ? 159.594 106.949 159.557 1.00 75.06  ? 405 PHE D CE2 1 
ATOM   17274 C CZ  . PHE D 1 405 ? 158.235 106.766 159.858 1.00 75.07  ? 405 PHE D CZ  1 
ATOM   17275 N N   . ILE D 1 406 ? 161.761 110.825 158.142 1.00 68.69  ? 406 ILE D N   1 
ATOM   17276 C CA  . ILE D 1 406 ? 162.777 111.044 159.175 1.00 65.33  ? 406 ILE D CA  1 
ATOM   17277 C C   . ILE D 1 406 ? 162.758 112.502 159.647 1.00 69.17  ? 406 ILE D C   1 
ATOM   17278 O O   . ILE D 1 406 ? 162.732 112.742 160.847 1.00 87.94  ? 406 ILE D O   1 
ATOM   17279 C CB  . ILE D 1 406 ? 164.169 110.607 158.670 1.00 67.21  ? 406 ILE D CB  1 
ATOM   17280 C CG1 . ILE D 1 406 ? 164.205 109.082 158.450 1.00 68.58  ? 406 ILE D CG1 1 
ATOM   17281 C CG2 . ILE D 1 406 ? 165.285 111.012 159.642 1.00 68.28  ? 406 ILE D CG2 1 
ATOM   17282 C CD1 . ILE D 1 406 ? 165.363 108.626 157.563 1.00 74.99  ? 406 ILE D CD1 1 
ATOM   17283 N N   . PHE D 1 407 ? 162.687 113.477 158.740 1.00 60.96  ? 407 PHE D N   1 
ATOM   17284 C CA  . PHE D 1 407 ? 162.573 114.890 159.092 1.00 67.32  ? 407 PHE D CA  1 
ATOM   17285 C C   . PHE D 1 407 ? 161.362 115.137 159.992 1.00 79.83  ? 407 PHE D C   1 
ATOM   17286 O O   . PHE D 1 407 ? 161.460 115.829 161.000 1.00 84.43  ? 407 PHE D O   1 
ATOM   17287 C CB  . PHE D 1 407 ? 162.490 115.729 157.811 1.00 71.22  ? 407 PHE D CB  1 
ATOM   17288 C CG  . PHE D 1 407 ? 163.112 117.103 157.896 1.00 76.40  ? 407 PHE D CG  1 
ATOM   17289 C CD1 . PHE D 1 407 ? 162.630 118.075 158.787 1.00 75.16  ? 407 PHE D CD1 1 
ATOM   17290 C CD2 . PHE D 1 407 ? 164.198 117.411 157.068 1.00 76.93  ? 407 PHE D CD2 1 
ATOM   17291 C CE1 . PHE D 1 407 ? 163.232 119.338 158.846 1.00 73.49  ? 407 PHE D CE1 1 
ATOM   17292 C CE2 . PHE D 1 407 ? 164.801 118.669 157.135 1.00 74.88  ? 407 PHE D CE2 1 
ATOM   17293 C CZ  . PHE D 1 407 ? 164.325 119.635 158.025 1.00 70.98  ? 407 PHE D CZ  1 
ATOM   17294 N N   . THR D 1 408 ? 160.217 114.539 159.671 1.00 75.99  ? 408 THR D N   1 
ATOM   17295 C CA  . THR D 1 408 ? 158.965 114.731 160.411 1.00 73.29  ? 408 THR D CA  1 
ATOM   17296 C C   . THR D 1 408 ? 158.981 114.062 161.786 1.00 73.79  ? 408 THR D C   1 
ATOM   17297 O O   . THR D 1 408 ? 158.598 114.694 162.760 1.00 79.83  ? 408 THR D O   1 
ATOM   17298 C CB  . THR D 1 408 ? 157.790 114.232 159.567 1.00 67.06  ? 408 THR D CB  1 
ATOM   17299 O OG1 . THR D 1 408 ? 157.801 114.914 158.341 1.00 69.35  ? 408 THR D OG1 1 
ATOM   17300 C CG2 . THR D 1 408 ? 156.432 114.487 160.198 1.00 64.39  ? 408 THR D CG2 1 
ATOM   17301 N N   . VAL D 1 409 ? 159.475 112.827 161.885 1.00 66.22  ? 409 VAL D N   1 
ATOM   17302 C CA  . VAL D 1 409 ? 159.636 112.012 163.091 1.00 68.55  ? 409 VAL D CA  1 
ATOM   17303 C C   . VAL D 1 409 ? 160.695 112.577 164.042 1.00 71.93  ? 409 VAL D C   1 
ATOM   17304 O O   . VAL D 1 409 ? 160.689 112.203 165.210 1.00 83.55  ? 409 VAL D O   1 
ATOM   17305 C CB  . VAL D 1 409 ? 159.921 110.557 162.668 1.00 74.79  ? 409 VAL D CB  1 
ATOM   17306 C CG1 . VAL D 1 409 ? 160.373 109.610 163.779 1.00 76.28  ? 409 VAL D CG1 1 
ATOM   17307 C CG2 . VAL D 1 409 ? 158.636 109.957 162.089 1.00 70.40  ? 409 VAL D CG2 1 
ATOM   17308 N N   . VAL D 1 410 ? 161.581 113.454 163.563 1.00 72.91  ? 410 VAL D N   1 
ATOM   17309 C CA  . VAL D 1 410 ? 162.585 114.185 164.355 1.00 79.45  ? 410 VAL D CA  1 
ATOM   17310 C C   . VAL D 1 410 ? 162.162 115.617 164.687 1.00 83.70  ? 410 VAL D C   1 
ATOM   17311 O O   . VAL D 1 410 ? 162.603 116.149 165.697 1.00 88.03  ? 410 VAL D O   1 
ATOM   17312 C CB  . VAL D 1 410 ? 163.933 114.192 163.616 1.00 76.40  ? 410 VAL D CB  1 
ATOM   17313 C CG1 . VAL D 1 410 ? 165.009 115.070 164.259 1.00 80.44  ? 410 VAL D CG1 1 
ATOM   17314 C CG2 . VAL D 1 410 ? 164.515 112.781 163.542 1.00 74.72  ? 410 VAL D CG2 1 
ATOM   17315 N N   . ALA D 1 411 ? 161.328 116.272 163.872 1.00 80.78  ? 411 ALA D N   1 
ATOM   17316 C CA  . ALA D 1 411 ? 160.757 117.582 164.189 1.00 78.05  ? 411 ALA D CA  1 
ATOM   17317 C C   . ALA D 1 411 ? 159.574 117.466 165.170 1.00 86.76  ? 411 ALA D C   1 
ATOM   17318 O O   . ALA D 1 411 ? 159.512 118.174 166.177 1.00 90.52  ? 411 ALA D O   1 
ATOM   17319 C CB  . ALA D 1 411 ? 160.367 118.269 162.882 1.00 72.12  ? 411 ALA D CB  1 
ATOM   17320 N N   . TYR D 1 412 ? 158.670 116.513 164.939 1.00 88.66  ? 412 TYR D N   1 
ATOM   17321 C CA  . TYR D 1 412 ? 157.904 115.896 166.017 1.00 84.02  ? 412 TYR D CA  1 
ATOM   17322 C C   . TYR D 1 412 ? 158.895 115.114 166.912 1.00 90.25  ? 412 TYR D C   1 
ATOM   17323 O O   . TYR D 1 412 ? 159.991 114.787 166.473 1.00 93.36  ? 412 TYR D O   1 
ATOM   17324 C CB  . TYR D 1 412 ? 156.812 115.022 165.379 1.00 84.90  ? 412 TYR D CB  1 
ATOM   17325 C CG  . TYR D 1 412 ? 155.626 114.686 166.260 1.00 92.19  ? 412 TYR D CG  1 
ATOM   17326 C CD1 . TYR D 1 412 ? 155.680 113.575 167.111 1.00 93.54  ? 412 TYR D CD1 1 
ATOM   17327 C CD2 . TYR D 1 412 ? 154.445 115.443 166.181 1.00 91.17  ? 412 TYR D CD2 1 
ATOM   17328 C CE1 . TYR D 1 412 ? 154.566 113.214 167.886 1.00 92.13  ? 412 TYR D CE1 1 
ATOM   17329 C CE2 . TYR D 1 412 ? 153.320 115.082 166.948 1.00 89.83  ? 412 TYR D CE2 1 
ATOM   17330 C CZ  . TYR D 1 412 ? 153.377 113.957 167.795 1.00 93.93  ? 412 TYR D CZ  1 
ATOM   17331 O OH  . TYR D 1 412 ? 152.300 113.572 168.528 1.00 92.31  ? 412 TYR D OH  1 
ATOM   17332 N N   . HIS D 1 413 ? 158.585 114.827 168.173 1.00 97.67  ? 413 HIS D N   1 
ATOM   17333 C CA  . HIS D 1 413 ? 159.541 114.237 169.132 1.00 100.46 ? 413 HIS D CA  1 
ATOM   17334 C C   . HIS D 1 413 ? 160.816 115.064 169.432 1.00 100.85 ? 413 HIS D C   1 
ATOM   17335 O O   . HIS D 1 413 ? 161.762 114.527 170.007 1.00 102.82 ? 413 HIS D O   1 
ATOM   17336 C CB  . HIS D 1 413 ? 159.913 112.779 168.799 1.00 93.58  ? 413 HIS D CB  1 
ATOM   17337 C CG  . HIS D 1 413 ? 158.807 111.881 168.333 1.00 96.33  ? 413 HIS D CG  1 
ATOM   17338 N ND1 . HIS D 1 413 ? 158.690 111.374 167.065 1.00 98.91  ? 413 HIS D ND1 1 
ATOM   17339 C CD2 . HIS D 1 413 ? 157.827 111.303 169.088 1.00 99.33  ? 413 HIS D CD2 1 
ATOM   17340 C CE1 . HIS D 1 413 ? 157.668 110.508 167.043 1.00 100.32 ? 413 HIS D CE1 1 
ATOM   17341 N NE2 . HIS D 1 413 ? 157.102 110.434 168.259 1.00 100.91 ? 413 HIS D NE2 1 
ATOM   17342 N N   . GLN D 1 414 ? 160.857 116.371 169.139 1.00 99.43  ? 414 GLN D N   1 
ATOM   17343 C CA  . GLN D 1 414 ? 161.880 117.255 169.717 1.00 100.79 ? 414 GLN D CA  1 
ATOM   17344 C C   . GLN D 1 414 ? 161.744 117.314 171.252 1.00 109.94 ? 414 GLN D C   1 
ATOM   17345 O O   . GLN D 1 414 ? 160.618 117.307 171.764 1.00 107.66 ? 414 GLN D O   1 
ATOM   17346 C CB  . GLN D 1 414 ? 161.789 118.684 169.153 1.00 98.31  ? 414 GLN D CB  1 
ATOM   17347 C CG  . GLN D 1 414 ? 162.414 118.844 167.768 1.00 100.12 ? 414 GLN D CG  1 
ATOM   17348 C CD  . GLN D 1 414 ? 163.923 118.639 167.779 1.00 105.78 ? 414 GLN D CD  1 
ATOM   17349 O OE1 . GLN D 1 414 ? 164.679 119.420 168.331 1.00 107.67 ? 414 GLN D OE1 1 
ATOM   17350 N NE2 . GLN D 1 414 ? 164.412 117.589 167.178 1.00 104.06 ? 414 GLN D NE2 1 
ATOM   17351 N N   . PRO D 1 415 ? 162.854 117.408 172.005 1.00 121.57 ? 415 PRO D N   1 
ATOM   17352 C CA  . PRO D 1 415 ? 162.828 117.596 173.450 1.00 116.29 ? 415 PRO D CA  1 
ATOM   17353 C C   . PRO D 1 415 ? 162.415 119.027 173.831 1.00 116.14 ? 415 PRO D C   1 
ATOM   17354 O O   . PRO D 1 415 ? 162.426 119.937 173.000 1.00 112.02 ? 415 PRO D O   1 
ATOM   17355 C CB  . PRO D 1 415 ? 164.249 117.270 173.910 1.00 114.52 ? 415 PRO D CB  1 
ATOM   17356 C CG  . PRO D 1 415 ? 165.102 117.718 172.729 1.00 114.62 ? 415 PRO D CG  1 
ATOM   17357 C CD  . PRO D 1 415 ? 164.226 117.376 171.528 1.00 116.43 ? 415 PRO D CD  1 
ATOM   17358 N N   . SER D 1 416 ? 162.082 119.240 175.103 1.00 124.40 ? 416 SER D N   1 
ATOM   17359 C CA  . SER D 1 416 ? 161.818 120.573 175.661 1.00 126.27 ? 416 SER D CA  1 
ATOM   17360 C C   . SER D 1 416 ? 163.040 121.494 175.545 1.00 125.42 ? 416 SER D C   1 
ATOM   17361 O O   . SER D 1 416 ? 164.181 121.043 175.632 1.00 123.39 ? 416 SER D O   1 
ATOM   17362 C CB  . SER D 1 416 ? 161.398 120.472 177.127 1.00 125.23 ? 416 SER D CB  1 
ATOM   17363 O OG  . SER D 1 416 ? 160.311 119.575 177.267 1.00 122.52 ? 416 SER D OG  1 
ATOM   17364 N N   . LEU D 1 417 ? 162.818 122.794 175.363 1.00 125.30 ? 417 LEU D N   1 
ATOM   17365 C CA  . LEU D 1 417 ? 163.835 123.749 174.911 1.00 126.14 ? 417 LEU D CA  1 
ATOM   17366 C C   . LEU D 1 417 ? 163.669 125.087 175.636 1.00 123.13 ? 417 LEU D C   1 
ATOM   17367 O O   . LEU D 1 417 ? 164.655 125.754 175.967 1.00 120.08 ? 417 LEU D O   1 
ATOM   17368 C CB  . LEU D 1 417 ? 163.705 123.868 173.377 1.00 125.06 ? 417 LEU D CB  1 
ATOM   17369 C CG  . LEU D 1 417 ? 164.599 124.914 172.695 1.00 124.70 ? 417 LEU D CG  1 
ATOM   17370 C CD1 . LEU D 1 417 ? 166.072 124.570 172.867 1.00 122.84 ? 417 LEU D CD1 1 
ATOM   17371 C CD2 . LEU D 1 417 ? 164.257 124.974 171.207 1.00 120.43 ? 417 LEU D CD2 1 
ATOM   17372 N N   . PHE D 1 429 ? 167.162 104.396 174.559 1.00 127.92 ? 429 PHE D N   1 
ATOM   17373 C CA  . PHE D 1 429 ? 167.207 104.115 173.128 1.00 131.16 ? 429 PHE D CA  1 
ATOM   17374 C C   . PHE D 1 429 ? 166.605 105.257 172.296 1.00 132.75 ? 429 PHE D C   1 
ATOM   17375 O O   . PHE D 1 429 ? 167.140 105.624 171.251 1.00 130.26 ? 429 PHE D O   1 
ATOM   17376 C CB  . PHE D 1 429 ? 166.470 102.797 172.870 1.00 129.67 ? 429 PHE D CB  1 
ATOM   17377 C CG  . PHE D 1 429 ? 166.329 102.406 171.411 1.00 130.30 ? 429 PHE D CG  1 
ATOM   17378 C CD1 . PHE D 1 429 ? 167.446 101.958 170.690 1.00 129.80 ? 429 PHE D CD1 1 
ATOM   17379 C CD2 . PHE D 1 429 ? 165.073 102.459 170.783 1.00 131.03 ? 429 PHE D CD2 1 
ATOM   17380 C CE1 . PHE D 1 429 ? 167.307 101.563 169.350 1.00 130.68 ? 429 PHE D CE1 1 
ATOM   17381 C CE2 . PHE D 1 429 ? 164.934 102.055 169.445 1.00 131.18 ? 429 PHE D CE2 1 
ATOM   17382 C CZ  . PHE D 1 429 ? 166.048 101.605 168.728 1.00 131.08 ? 429 PHE D CZ  1 
ATOM   17383 N N   . GLY D 1 430 ? 165.528 105.880 172.776 1.00 130.45 ? 430 GLY D N   1 
ATOM   17384 C CA  . GLY D 1 430 ? 164.866 106.982 172.073 1.00 127.16 ? 430 GLY D CA  1 
ATOM   17385 C C   . GLY D 1 430 ? 165.779 108.194 171.850 1.00 129.67 ? 430 GLY D C   1 
ATOM   17386 O O   . GLY D 1 430 ? 165.721 108.819 170.794 1.00 131.89 ? 430 GLY D O   1 
ATOM   17387 N N   . GLU D 1 431 ? 166.671 108.499 172.791 1.00 126.26 ? 431 GLU D N   1 
ATOM   17388 C CA  . GLU D 1 431 ? 167.615 109.614 172.685 1.00 123.51 ? 431 GLU D CA  1 
ATOM   17389 C C   . GLU D 1 431 ? 168.740 109.371 171.669 1.00 126.03 ? 431 GLU D C   1 
ATOM   17390 O O   . GLU D 1 431 ? 169.104 110.287 170.931 1.00 125.58 ? 431 GLU D O   1 
ATOM   17391 C CB  . GLU D 1 431 ? 168.211 109.885 174.061 1.00 123.23 ? 431 GLU D CB  1 
ATOM   17392 N N   . SER D 1 432 ? 169.280 108.151 171.569 1.00 124.57 ? 432 SER D N   1 
ATOM   17393 C CA  . SER D 1 432 ? 170.293 107.829 170.552 1.00 124.71 ? 432 SER D CA  1 
ATOM   17394 C C   . SER D 1 432 ? 169.676 107.690 169.157 1.00 123.61 ? 432 SER D C   1 
ATOM   17395 O O   . SER D 1 432 ? 170.274 108.144 168.186 1.00 121.10 ? 432 SER D O   1 
ATOM   17396 C CB  . SER D 1 432 ? 171.097 106.585 170.930 1.00 124.59 ? 432 SER D CB  1 
ATOM   17397 O OG  . SER D 1 432 ? 170.288 105.433 170.978 1.00 126.04 ? 432 SER D OG  1 
ATOM   17398 N N   . MET D 1 433 ? 168.447 107.180 169.034 1.00 119.73 ? 433 MET D N   1 
ATOM   17399 C CA  . MET D 1 433 ? 167.698 107.220 167.771 1.00 117.77 ? 433 MET D CA  1 
ATOM   17400 C C   . MET D 1 433 ? 167.321 108.645 167.348 1.00 116.59 ? 433 MET D C   1 
ATOM   17401 O O   . MET D 1 433 ? 167.346 108.949 166.157 1.00 117.79 ? 433 MET D O   1 
ATOM   17402 C CB  . MET D 1 433 ? 166.443 106.347 167.860 1.00 118.17 ? 433 MET D CB  1 
ATOM   17403 C CG  . MET D 1 433 ? 166.789 104.858 167.946 1.00 122.27 ? 433 MET D CG  1 
ATOM   17404 S SD  . MET D 1 433 ? 167.723 104.177 166.546 1.00 128.14 ? 433 MET D SD  1 
ATOM   17405 C CE  . MET D 1 433 ? 166.469 104.277 165.249 1.00 118.10 ? 433 MET D CE  1 
ATOM   17406 N N   . LEU D 1 434 ? 167.032 109.554 168.281 1.00 111.55 ? 434 LEU D N   1 
ATOM   17407 C CA  . LEU D 1 434 ? 166.862 110.976 167.969 1.00 110.24 ? 434 LEU D CA  1 
ATOM   17408 C C   . LEU D 1 434 ? 168.170 111.593 167.459 1.00 112.54 ? 434 LEU D C   1 
ATOM   17409 O O   . LEU D 1 434 ? 168.153 112.305 166.457 1.00 115.42 ? 434 LEU D O   1 
ATOM   17410 C CB  . LEU D 1 434 ? 166.316 111.723 169.198 1.00 110.04 ? 434 LEU D CB  1 
ATOM   17411 C CG  . LEU D 1 434 ? 166.190 113.243 169.004 1.00 111.05 ? 434 LEU D CG  1 
ATOM   17412 C CD1 . LEU D 1 434 ? 165.146 113.596 167.951 1.00 110.75 ? 434 LEU D CD1 1 
ATOM   17413 C CD2 . LEU D 1 434 ? 165.801 113.915 170.314 1.00 112.38 ? 434 LEU D CD2 1 
ATOM   17414 N N   . LEU D 1 435 ? 169.313 111.307 168.094 1.00 110.77 ? 435 LEU D N   1 
ATOM   17415 C CA  . LEU D 1 435 ? 170.612 111.782 167.604 1.00 111.60 ? 435 LEU D CA  1 
ATOM   17416 C C   . LEU D 1 435 ? 170.931 111.245 166.198 1.00 108.60 ? 435 LEU D C   1 
ATOM   17417 O O   . LEU D 1 435 ? 171.328 112.018 165.329 1.00 106.05 ? 435 LEU D O   1 
ATOM   17418 C CB  . LEU D 1 435 ? 171.705 111.414 168.623 1.00 113.83 ? 435 LEU D CB  1 
ATOM   17419 C CG  . LEU D 1 435 ? 173.127 111.846 168.221 1.00 113.99 ? 435 LEU D CG  1 
ATOM   17420 C CD1 . LEU D 1 435 ? 173.242 113.361 168.053 1.00 109.57 ? 435 LEU D CD1 1 
ATOM   17421 C CD2 . LEU D 1 435 ? 174.105 111.400 169.304 1.00 109.92 ? 435 LEU D CD2 1 
ATOM   17422 N N   . LEU D 1 436 ? 170.700 109.952 165.939 1.00 101.39 ? 436 LEU D N   1 
ATOM   17423 C CA  . LEU D 1 436 ? 170.823 109.367 164.602 1.00 101.16 ? 436 LEU D CA  1 
ATOM   17424 C C   . LEU D 1 436 ? 169.940 110.113 163.596 1.00 105.16 ? 436 LEU D C   1 
ATOM   17425 O O   . LEU D 1 436 ? 170.417 110.493 162.534 1.00 106.75 ? 436 LEU D O   1 
ATOM   17426 C CB  . LEU D 1 436 ? 170.464 107.872 164.672 1.00 101.15 ? 436 LEU D CB  1 
ATOM   17427 C CG  . LEU D 1 436 ? 170.403 107.162 163.309 1.00 99.96  ? 436 LEU D CG  1 
ATOM   17428 C CD1 . LEU D 1 436 ? 171.763 107.138 162.621 1.00 102.06 ? 436 LEU D CD1 1 
ATOM   17429 C CD2 . LEU D 1 436 ? 169.931 105.731 163.500 1.00 98.01  ? 436 LEU D CD2 1 
ATOM   17430 N N   . GLY D 1 437 ? 168.682 110.385 163.943 1.00 97.04  ? 437 GLY D N   1 
ATOM   17431 C CA  . GLY D 1 437 ? 167.769 111.155 163.106 1.00 89.54  ? 437 GLY D CA  1 
ATOM   17432 C C   . GLY D 1 437 ? 168.312 112.540 162.753 1.00 92.60  ? 437 GLY D C   1 
ATOM   17433 O O   . GLY D 1 437 ? 168.267 112.930 161.590 1.00 102.82 ? 437 GLY D O   1 
ATOM   17434 N N   . HIS D 1 438 ? 168.897 113.264 163.706 1.00 92.79  ? 438 HIS D N   1 
ATOM   17435 C CA  . HIS D 1 438 ? 169.549 114.549 163.432 1.00 91.74  ? 438 HIS D CA  1 
ATOM   17436 C C   . HIS D 1 438 ? 170.750 114.427 162.489 1.00 97.22  ? 438 HIS D C   1 
ATOM   17437 O O   . HIS D 1 438 ? 170.912 115.264 161.604 1.00 99.10  ? 438 HIS D O   1 
ATOM   17438 C CB  . HIS D 1 438 ? 169.971 115.211 164.747 1.00 96.29  ? 438 HIS D CB  1 
ATOM   17439 C CG  . HIS D 1 438 ? 168.862 116.009 165.364 1.00 99.01  ? 438 HIS D CG  1 
ATOM   17440 N ND1 . HIS D 1 438 ? 168.409 117.222 164.909 1.00 100.22 ? 438 HIS D ND1 1 
ATOM   17441 C CD2 . HIS D 1 438 ? 168.072 115.650 166.417 1.00 97.99  ? 438 HIS D CD2 1 
ATOM   17442 C CE1 . HIS D 1 438 ? 167.379 117.598 165.681 1.00 97.76  ? 438 HIS D CE1 1 
ATOM   17443 N NE2 . HIS D 1 438 ? 167.144 116.674 166.623 1.00 98.42  ? 438 HIS D NE2 1 
ATOM   17444 N N   . ILE D 1 439 ? 171.578 113.390 162.625 1.00 102.72 ? 439 ILE D N   1 
ATOM   17445 C CA  . ILE D 1 439 ? 172.705 113.158 161.712 1.00 98.95  ? 439 ILE D CA  1 
ATOM   17446 C C   . ILE D 1 439 ? 172.214 112.781 160.308 1.00 95.88  ? 439 ILE D C   1 
ATOM   17447 O O   . ILE D 1 439 ? 172.698 113.343 159.331 1.00 98.40  ? 439 ILE D O   1 
ATOM   17448 C CB  . ILE D 1 439 ? 173.685 112.124 162.303 1.00 98.32  ? 439 ILE D CB  1 
ATOM   17449 C CG1 . ILE D 1 439 ? 174.338 112.623 163.610 1.00 99.75  ? 439 ILE D CG1 1 
ATOM   17450 C CG2 . ILE D 1 439 ? 174.776 111.737 161.299 1.00 94.53  ? 439 ILE D CG2 1 
ATOM   17451 C CD1 . ILE D 1 439 ? 175.104 113.938 163.529 1.00 95.58  ? 439 ILE D CD1 1 
ATOM   17452 N N   . LEU D 1 440 ? 171.213 111.912 160.168 1.00 84.91  ? 440 LEU D N   1 
ATOM   17453 C CA  . LEU D 1 440 ? 170.612 111.622 158.867 1.00 86.53  ? 440 LEU D CA  1 
ATOM   17454 C C   . LEU D 1 440 ? 169.996 112.865 158.212 1.00 87.07  ? 440 LEU D C   1 
ATOM   17455 O O   . LEU D 1 440 ? 170.136 113.043 157.009 1.00 93.38  ? 440 LEU D O   1 
ATOM   17456 C CB  . LEU D 1 440 ? 169.572 110.500 159.012 1.00 88.65  ? 440 LEU D CB  1 
ATOM   17457 C CG  . LEU D 1 440 ? 170.155 109.139 159.421 1.00 92.38  ? 440 LEU D CG  1 
ATOM   17458 C CD1 . LEU D 1 440 ? 169.020 108.146 159.647 1.00 89.27  ? 440 LEU D CD1 1 
ATOM   17459 C CD2 . LEU D 1 440 ? 171.081 108.566 158.357 1.00 90.98  ? 440 LEU D CD2 1 
ATOM   17460 N N   . ILE D 1 441 ? 169.372 113.766 158.973 1.00 77.31  ? 441 ILE D N   1 
ATOM   17461 C CA  . ILE D 1 441 ? 168.869 115.046 158.451 1.00 79.97  ? 441 ILE D CA  1 
ATOM   17462 C C   . ILE D 1 441 ? 170.013 115.977 158.051 1.00 85.35  ? 441 ILE D C   1 
ATOM   17463 O O   . ILE D 1 441 ? 169.922 116.610 157.006 1.00 92.07  ? 441 ILE D O   1 
ATOM   17464 C CB  . ILE D 1 441 ? 167.922 115.707 159.467 1.00 84.82  ? 441 ILE D CB  1 
ATOM   17465 C CG1 . ILE D 1 441 ? 166.615 114.903 159.520 1.00 84.98  ? 441 ILE D CG1 1 
ATOM   17466 C CG2 . ILE D 1 441 ? 167.597 117.169 159.135 1.00 85.37  ? 441 ILE D CG2 1 
ATOM   17467 C CD1 . ILE D 1 441 ? 165.822 115.189 160.787 1.00 90.96  ? 441 ILE D CD1 1 
ATOM   17468 N N   . LEU D 1 442 ? 171.105 116.051 158.814 1.00 78.79  ? 442 LEU D N   1 
ATOM   17469 C CA  . LEU D 1 442 ? 172.291 116.822 158.430 1.00 77.73  ? 442 LEU D CA  1 
ATOM   17470 C C   . LEU D 1 442 ? 172.880 116.302 157.111 1.00 82.34  ? 442 LEU D C   1 
ATOM   17471 O O   . LEU D 1 442 ? 173.120 117.082 156.198 1.00 82.72  ? 442 LEU D O   1 
ATOM   17472 C CB  . LEU D 1 442 ? 173.325 116.766 159.568 1.00 81.79  ? 442 LEU D CB  1 
ATOM   17473 C CG  . LEU D 1 442 ? 174.639 117.504 159.262 1.00 83.38  ? 442 LEU D CG  1 
ATOM   17474 C CD1 . LEU D 1 442 ? 174.452 119.010 159.215 1.00 79.60  ? 442 LEU D CD1 1 
ATOM   17475 C CD2 . LEU D 1 442 ? 175.670 117.174 160.330 1.00 80.70  ? 442 LEU D CD2 1 
ATOM   17476 N N   . LEU D 1 443 ? 173.081 114.990 156.984 1.00 88.96  ? 443 LEU D N   1 
ATOM   17477 C CA  . LEU D 1 443 ? 173.628 114.370 155.778 1.00 81.90  ? 443 LEU D CA  1 
ATOM   17478 C C   . LEU D 1 443 ? 172.692 114.496 154.573 1.00 80.39  ? 443 LEU D C   1 
ATOM   17479 O O   . LEU D 1 443 ? 173.153 114.852 153.497 1.00 87.10  ? 443 LEU D O   1 
ATOM   17480 C CB  . LEU D 1 443 ? 173.965 112.897 156.045 1.00 81.91  ? 443 LEU D CB  1 
ATOM   17481 C CG  . LEU D 1 443 ? 175.104 112.665 157.049 1.00 86.02  ? 443 LEU D CG  1 
ATOM   17482 C CD1 . LEU D 1 443 ? 175.315 111.164 157.207 1.00 84.20  ? 443 LEU D CD1 1 
ATOM   17483 C CD2 . LEU D 1 443 ? 176.424 113.296 156.611 1.00 83.01  ? 443 LEU D CD2 1 
ATOM   17484 N N   . GLY D 1 444 ? 171.383 114.291 154.731 1.00 69.94  ? 444 GLY D N   1 
ATOM   17485 C CA  . GLY D 1 444 ? 170.405 114.560 153.675 1.00 72.89  ? 444 GLY D CA  1 
ATOM   17486 C C   . GLY D 1 444 ? 170.333 116.039 153.284 1.00 73.53  ? 444 GLY D C   1 
ATOM   17487 O O   . GLY D 1 444 ? 170.196 116.360 152.109 1.00 81.71  ? 444 GLY D O   1 
ATOM   17488 N N   . GLY D 1 445 ? 170.510 116.956 154.236 1.00 71.25  ? 445 GLY D N   1 
ATOM   17489 C CA  . GLY D 1 445 ? 170.563 118.391 153.982 1.00 68.09  ? 445 GLY D CA  1 
ATOM   17490 C C   . GLY D 1 445 ? 171.835 118.828 153.268 1.00 71.66  ? 445 GLY D C   1 
ATOM   17491 O O   . GLY D 1 445 ? 171.753 119.583 152.310 1.00 82.65  ? 445 GLY D O   1 
ATOM   17492 N N   . ILE D 1 446 ? 173.005 118.300 153.634 1.00 74.69  ? 446 ILE D N   1 
ATOM   17493 C CA  . ILE D 1 446 ? 174.258 118.527 152.901 1.00 71.63  ? 446 ILE D CA  1 
ATOM   17494 C C   . ILE D 1 446 ? 174.192 117.895 151.508 1.00 78.33  ? 446 ILE D C   1 
ATOM   17495 O O   . ILE D 1 446 ? 174.559 118.547 150.539 1.00 82.97  ? 446 ILE D O   1 
ATOM   17496 C CB  . ILE D 1 446 ? 175.466 118.005 153.708 1.00 75.36  ? 446 ILE D CB  1 
ATOM   17497 C CG1 . ILE D 1 446 ? 175.699 118.901 154.941 1.00 80.31  ? 446 ILE D CG1 1 
ATOM   17498 C CG2 . ILE D 1 446 ? 176.746 117.951 152.856 1.00 74.32  ? 446 ILE D CG2 1 
ATOM   17499 C CD1 . ILE D 1 446 ? 176.705 118.325 155.943 1.00 77.39  ? 446 ILE D CD1 1 
ATOM   17500 N N   . TYR D 1 447 ? 173.687 116.668 151.367 1.00 76.24  ? 447 TYR D N   1 
ATOM   17501 C CA  . TYR D 1 447 ? 173.532 116.025 150.064 1.00 66.08  ? 447 TYR D CA  1 
ATOM   17502 C C   . TYR D 1 447 ? 172.680 116.863 149.111 1.00 71.03  ? 447 TYR D C   1 
ATOM   17503 O O   . TYR D 1 447 ? 173.101 117.136 147.992 1.00 82.24  ? 447 TYR D O   1 
ATOM   17504 C CB  . TYR D 1 447 ? 172.931 114.628 150.241 1.00 68.44  ? 447 TYR D CB  1 
ATOM   17505 C CG  . TYR D 1 447 ? 172.751 113.906 148.927 1.00 76.93  ? 447 TYR D CG  1 
ATOM   17506 C CD1 . TYR D 1 447 ? 171.611 114.144 148.138 1.00 78.63  ? 447 TYR D CD1 1 
ATOM   17507 C CD2 . TYR D 1 447 ? 173.770 113.066 148.452 1.00 76.57  ? 447 TYR D CD2 1 
ATOM   17508 C CE1 . TYR D 1 447 ? 171.514 113.598 146.846 1.00 72.39  ? 447 TYR D CE1 1 
ATOM   17509 C CE2 . TYR D 1 447 ? 173.669 112.504 147.172 1.00 79.34  ? 447 TYR D CE2 1 
ATOM   17510 C CZ  . TYR D 1 447 ? 172.558 112.792 146.354 1.00 79.94  ? 447 TYR D CZ  1 
ATOM   17511 O OH  . TYR D 1 447 ? 172.503 112.314 145.087 1.00 86.69  ? 447 TYR D OH  1 
ATOM   17512 N N   . LEU D 1 448 ? 171.499 117.312 149.547 1.00 65.29  ? 448 LEU D N   1 
ATOM   17513 C CA  . LEU D 1 448 ? 170.637 118.181 148.751 1.00 60.17  ? 448 LEU D CA  1 
ATOM   17514 C C   . LEU D 1 448 ? 171.256 119.564 148.527 1.00 65.26  ? 448 LEU D C   1 
ATOM   17515 O O   . LEU D 1 448 ? 171.116 120.095 147.430 1.00 78.23  ? 448 LEU D O   1 
ATOM   17516 C CB  . LEU D 1 448 ? 169.266 118.307 149.426 1.00 70.71  ? 448 LEU D CB  1 
ATOM   17517 C CG  . LEU D 1 448 ? 168.419 117.026 149.394 1.00 67.39  ? 448 LEU D CG  1 
ATOM   17518 C CD1 . LEU D 1 448 ? 167.226 117.193 150.322 1.00 70.87  ? 448 LEU D CD1 1 
ATOM   17519 C CD2 . LEU D 1 448 ? 167.879 116.738 147.997 1.00 70.72  ? 448 LEU D CD2 1 
ATOM   17520 N N   . LEU D 1 449 ? 171.974 120.140 149.499 1.00 68.74  ? 449 LEU D N   1 
ATOM   17521 C CA  . LEU D 1 449 ? 172.674 121.411 149.296 1.00 67.55  ? 449 LEU D CA  1 
ATOM   17522 C C   . LEU D 1 449 ? 173.733 121.269 148.208 1.00 74.26  ? 449 LEU D C   1 
ATOM   17523 O O   . LEU D 1 449 ? 173.766 122.072 147.277 1.00 75.08  ? 449 LEU D O   1 
ATOM   17524 C CB  . LEU D 1 449 ? 173.280 121.890 150.626 1.00 71.52  ? 449 LEU D CB  1 
ATOM   17525 C CG  . LEU D 1 449 ? 174.098 123.183 150.539 1.00 74.06  ? 449 LEU D CG  1 
ATOM   17526 C CD1 . LEU D 1 449 ? 173.272 124.333 149.992 1.00 74.40  ? 449 LEU D CD1 1 
ATOM   17527 C CD2 . LEU D 1 449 ? 174.584 123.575 151.925 1.00 72.98  ? 449 LEU D CD2 1 
ATOM   17528 N N   . LEU D 1 450 ? 174.562 120.219 148.213 1.00 79.71  ? 450 LEU D N   1 
ATOM   17529 C CA  . LEU D 1 450 ? 175.554 119.967 147.158 1.00 74.41  ? 450 LEU D CA  1 
ATOM   17530 C C   . LEU D 1 450 ? 174.922 119.657 145.794 1.00 74.77  ? 450 LEU D C   1 
ATOM   17531 O O   . LEU D 1 450 ? 175.364 120.189 144.782 1.00 78.02  ? 450 LEU D O   1 
ATOM   17532 C CB  . LEU D 1 450 ? 176.487 118.821 147.573 1.00 73.59  ? 450 LEU D CB  1 
ATOM   17533 C CG  . LEU D 1 450 ? 177.408 119.143 148.753 1.00 76.25  ? 450 LEU D CG  1 
ATOM   17534 C CD1 . LEU D 1 450 ? 178.249 117.915 149.076 1.00 74.01  ? 450 LEU D CD1 1 
ATOM   17535 C CD2 . LEU D 1 450 ? 178.352 120.304 148.459 1.00 72.64  ? 450 LEU D CD2 1 
ATOM   17536 N N   . GLY D 1 451 ? 173.865 118.849 145.748 1.00 77.34  ? 451 GLY D N   1 
ATOM   17537 C CA  . GLY D 1 451 ? 173.136 118.557 144.516 1.00 69.98  ? 451 GLY D CA  1 
ATOM   17538 C C   . GLY D 1 451 ? 172.524 119.794 143.854 1.00 70.93  ? 451 GLY D C   1 
ATOM   17539 O O   . GLY D 1 451 ? 172.610 119.932 142.634 1.00 78.23  ? 451 GLY D O   1 
ATOM   17540 N N   . GLN D 1 452 ? 171.957 120.733 144.618 1.00 73.99  ? 452 GLN D N   1 
ATOM   17541 C CA  . GLN D 1 452 ? 171.421 121.972 144.047 1.00 74.64  ? 452 GLN D CA  1 
ATOM   17542 C C   . GLN D 1 452 ? 172.493 123.018 143.724 1.00 71.10  ? 452 GLN D C   1 
ATOM   17543 O O   . GLN D 1 452 ? 172.358 123.731 142.734 1.00 80.57  ? 452 GLN D O   1 
ATOM   17544 C CB  . GLN D 1 452 ? 170.361 122.578 144.970 1.00 71.00  ? 452 GLN D CB  1 
ATOM   17545 C CG  . GLN D 1 452 ? 169.113 121.707 145.135 1.00 68.84  ? 452 GLN D CG  1 
ATOM   17546 C CD  . GLN D 1 452 ? 168.449 121.317 143.823 1.00 75.09  ? 452 GLN D CD  1 
ATOM   17547 O OE1 . GLN D 1 452 ? 168.344 120.151 143.485 1.00 80.89  ? 452 GLN D OE1 1 
ATOM   17548 N NE2 . GLN D 1 452 ? 167.989 122.248 143.024 1.00 71.97  ? 452 GLN D NE2 1 
ATOM   17549 N N   . LEU D 1 453 ? 173.585 123.108 144.484 1.00 68.67  ? 453 LEU D N   1 
ATOM   17550 C CA  . LEU D 1 453 ? 174.711 123.958 144.083 1.00 73.51  ? 453 LEU D CA  1 
ATOM   17551 C C   . LEU D 1 453 ? 175.368 123.442 142.794 1.00 75.71  ? 453 LEU D C   1 
ATOM   17552 O O   . LEU D 1 453 ? 175.736 124.245 141.943 1.00 80.49  ? 453 LEU D O   1 
ATOM   17553 C CB  . LEU D 1 453 ? 175.729 124.075 145.225 1.00 77.27  ? 453 LEU D CB  1 
ATOM   17554 C CG  . LEU D 1 453 ? 175.243 124.908 146.426 1.00 78.39  ? 453 LEU D CG  1 
ATOM   17555 C CD1 . LEU D 1 453 ? 176.257 124.800 147.554 1.00 71.75  ? 453 LEU D CD1 1 
ATOM   17556 C CD2 . LEU D 1 453 ? 175.089 126.383 146.085 1.00 73.75  ? 453 LEU D CD2 1 
ATOM   17557 N N   . TRP D 1 454 ? 175.443 122.126 142.579 1.00 86.82  ? 454 TRP D N   1 
ATOM   17558 C CA  . TRP D 1 454 ? 175.873 121.561 141.298 1.00 81.58  ? 454 TRP D CA  1 
ATOM   17559 C C   . TRP D 1 454 ? 174.915 121.914 140.154 1.00 81.50  ? 454 TRP D C   1 
ATOM   17560 O O   . TRP D 1 454 ? 175.379 122.319 139.096 1.00 92.75  ? 454 TRP D O   1 
ATOM   17561 C CB  . TRP D 1 454 ? 176.047 120.049 141.430 1.00 82.21  ? 454 TRP D CB  1 
ATOM   17562 C CG  . TRP D 1 454 ? 176.644 119.354 140.246 1.00 88.16  ? 454 TRP D CG  1 
ATOM   17563 C CD1 . TRP D 1 454 ? 177.854 119.627 139.711 1.00 88.62  ? 454 TRP D CD1 1 
ATOM   17564 C CD2 . TRP D 1 454 ? 176.109 118.241 139.467 1.00 92.71  ? 454 TRP D CD2 1 
ATOM   17565 N NE1 . TRP D 1 454 ? 178.104 118.766 138.663 1.00 86.52  ? 454 TRP D NE1 1 
ATOM   17566 C CE2 . TRP D 1 454 ? 177.078 117.868 138.492 1.00 89.18  ? 454 TRP D CE2 1 
ATOM   17567 C CE3 . TRP D 1 454 ? 174.913 117.491 139.498 1.00 90.47  ? 454 TRP D CE3 1 
ATOM   17568 C CZ2 . TRP D 1 454 ? 176.885 116.796 137.611 1.00 88.34  ? 454 TRP D CZ2 1 
ATOM   17569 C CZ3 . TRP D 1 454 ? 174.704 116.419 138.607 1.00 89.71  ? 454 TRP D CZ3 1 
ATOM   17570 C CH2 . TRP D 1 454 ? 175.690 116.062 137.673 1.00 91.21  ? 454 TRP D CH2 1 
ATOM   17571 N N   . TYR D 1 455 ? 173.594 121.862 140.357 1.00 75.95  ? 455 TYR D N   1 
ATOM   17572 C CA  . TYR D 1 455 ? 172.619 122.315 139.356 1.00 73.95  ? 455 TYR D CA  1 
ATOM   17573 C C   . TYR D 1 455 ? 172.848 123.768 138.941 1.00 81.50  ? 455 TYR D C   1 
ATOM   17574 O O   . TYR D 1 455 ? 173.025 124.051 137.758 1.00 90.87  ? 455 TYR D O   1 
ATOM   17575 C CB  . TYR D 1 455 ? 171.186 122.116 139.858 1.00 78.80  ? 455 TYR D CB  1 
ATOM   17576 C CG  . TYR D 1 455 ? 170.128 122.599 138.886 1.00 83.25  ? 455 TYR D CG  1 
ATOM   17577 C CD1 . TYR D 1 455 ? 169.747 121.780 137.813 1.00 83.54  ? 455 TYR D CD1 1 
ATOM   17578 C CD2 . TYR D 1 455 ? 169.544 123.870 139.028 1.00 83.11  ? 455 TYR D CD2 1 
ATOM   17579 C CE1 . TYR D 1 455 ? 168.789 122.221 136.885 1.00 82.29  ? 455 TYR D CE1 1 
ATOM   17580 C CE2 . TYR D 1 455 ? 168.593 124.324 138.096 1.00 88.26  ? 455 TYR D CE2 1 
ATOM   17581 C CZ  . TYR D 1 455 ? 168.209 123.494 137.022 1.00 89.72  ? 455 TYR D CZ  1 
ATOM   17582 O OH  . TYR D 1 455 ? 167.283 123.902 136.120 1.00 88.48  ? 455 TYR D OH  1 
ATOM   17583 N N   . PHE D 1 456 ? 172.921 124.707 139.884 1.00 84.30  ? 456 PHE D N   1 
ATOM   17584 C CA  . PHE D 1 456 ? 173.154 126.112 139.547 1.00 82.51  ? 456 PHE D CA  1 
ATOM   17585 C C   . PHE D 1 456 ? 174.567 126.398 139.037 1.00 86.95  ? 456 PHE D C   1 
ATOM   17586 O O   . PHE D 1 456 ? 174.739 127.324 138.255 1.00 93.64  ? 456 PHE D O   1 
ATOM   17587 C CB  . PHE D 1 456 ? 172.788 127.002 140.729 1.00 77.34  ? 456 PHE D CB  1 
ATOM   17588 C CG  . PHE D 1 456 ? 171.303 126.994 141.025 1.00 83.67  ? 456 PHE D CG  1 
ATOM   17589 C CD1 . PHE D 1 456 ? 170.399 127.448 140.049 1.00 85.47  ? 456 PHE D CD1 1 
ATOM   17590 C CD2 . PHE D 1 456 ? 170.822 126.511 142.250 1.00 80.73  ? 456 PHE D CD2 1 
ATOM   17591 C CE1 . PHE D 1 456 ? 169.019 127.424 140.297 1.00 85.99  ? 456 PHE D CE1 1 
ATOM   17592 C CE2 . PHE D 1 456 ? 169.442 126.486 142.499 1.00 80.57  ? 456 PHE D CE2 1 
ATOM   17593 C CZ  . PHE D 1 456 ? 168.545 126.950 141.527 1.00 85.08  ? 456 PHE D CZ  1 
ATOM   17594 N N   . TRP D 1 457 ? 175.570 125.592 139.381 1.00 88.82  ? 457 TRP D N   1 
ATOM   17595 C CA  . TRP D 1 457 ? 176.887 125.674 138.749 1.00 85.95  ? 457 TRP D CA  1 
ATOM   17596 C C   . TRP D 1 457 ? 176.850 125.242 137.279 1.00 90.31  ? 457 TRP D C   1 
ATOM   17597 O O   . TRP D 1 457 ? 177.369 125.950 136.419 1.00 92.35  ? 457 TRP D O   1 
ATOM   17598 C CB  . TRP D 1 457 ? 177.897 124.836 139.531 1.00 87.83  ? 457 TRP D CB  1 
ATOM   17599 C CG  . TRP D 1 457 ? 179.240 124.759 138.888 1.00 92.15  ? 457 TRP D CG  1 
ATOM   17600 C CD1 . TRP D 1 457 ? 179.800 123.650 138.359 1.00 91.96  ? 457 TRP D CD1 1 
ATOM   17601 C CD2 . TRP D 1 457 ? 180.192 125.838 138.655 1.00 95.33  ? 457 TRP D CD2 1 
ATOM   17602 N NE1 . TRP D 1 457 ? 181.023 123.968 137.810 1.00 94.31  ? 457 TRP D NE1 1 
ATOM   17603 C CE2 . TRP D 1 457 ? 181.310 125.308 137.953 1.00 95.48  ? 457 TRP D CE2 1 
ATOM   17604 C CE3 . TRP D 1 457 ? 180.217 127.216 138.958 1.00 93.13  ? 457 TRP D CE3 1 
ATOM   17605 C CZ2 . TRP D 1 457 ? 182.390 126.107 137.555 1.00 93.18  ? 457 TRP D CZ2 1 
ATOM   17606 C CZ3 . TRP D 1 457 ? 181.296 128.024 138.564 1.00 92.66  ? 457 TRP D CZ3 1 
ATOM   17607 C CH2 . TRP D 1 457 ? 182.378 127.476 137.859 1.00 93.28  ? 457 TRP D CH2 1 
ATOM   17608 N N   . ARG D 1 458 ? 176.151 124.142 136.977 1.00 84.24  ? 458 ARG D N   1 
ATOM   17609 C CA  . ARG D 1 458 ? 176.032 123.655 135.570 1.00 83.51  ? 458 ARG D CA  1 
ATOM   17610 C C   . ARG D 1 458 ? 175.208 124.629 134.725 1.00 87.63  ? 458 ARG D C   1 
ATOM   17611 O O   . ARG D 1 458 ? 175.554 124.818 133.544 1.00 88.55  ? 458 ARG D O   1 
ATOM   17612 C CB  . ARG D 1 458 ? 175.388 122.263 135.550 1.00 80.25  ? 458 ARG D CB  1 
ATOM   17613 C CG  . ARG D 1 458 ? 176.384 121.173 135.954 1.00 78.39  ? 458 ARG D CG  1 
ATOM   17614 C CD  . ARG D 1 458 ? 175.856 119.775 135.631 1.00 81.57  ? 458 ARG D CD  1 
ATOM   17615 N NE  . ARG D 1 458 ? 174.817 119.326 136.574 1.00 86.68  ? 458 ARG D NE  1 
ATOM   17616 C CZ  . ARG D 1 458 ? 173.522 119.598 136.458 1.00 85.29  ? 458 ARG D CZ  1 
ATOM   17617 N NH1 . ARG D 1 458 ? 172.669 119.149 137.363 1.00 83.47  ? 458 ARG D NH1 1 
ATOM   17618 N NH2 . ARG D 1 458 ? 173.084 120.319 135.441 1.00 82.90  ? 458 ARG D NH2 1 
ATOM   17619 N N   . ARG D 1 459 ? 174.170 125.215 135.304 1.00 87.39  ? 459 ARG D N   1 
ATOM   17620 C CA  . ARG D 1 459 ? 173.236 126.146 134.644 1.00 91.00  ? 459 ARG D CA  1 
ATOM   17621 C C   . ARG D 1 459 ? 173.643 127.629 134.695 1.00 97.61  ? 459 ARG D C   1 
ATOM   17622 O O   . ARG D 1 459 ? 172.897 128.485 134.233 1.00 99.31  ? 459 ARG D O   1 
ATOM   17623 C CB  . ARG D 1 459 ? 171.826 125.888 135.202 1.00 89.14  ? 459 ARG D CB  1 
ATOM   17624 C CG  . ARG D 1 459 ? 171.315 124.445 134.994 1.00 89.40  ? 459 ARG D CG  1 
ATOM   17625 C CD  . ARG D 1 459 ? 171.192 124.022 133.527 1.00 87.51  ? 459 ARG D CD  1 
ATOM   17626 N NE  . ARG D 1 459 ? 171.062 122.560 133.387 1.00 91.41  ? 459 ARG D NE  1 
ATOM   17627 C CZ  . ARG D 1 459 ? 171.517 121.820 132.391 1.00 96.08  ? 459 ARG D CZ  1 
ATOM   17628 N NH1 . ARG D 1 459 ? 171.337 120.536 132.405 1.00 89.26  ? 459 ARG D NH1 1 
ATOM   17629 N NH2 . ARG D 1 459 ? 172.164 122.325 131.381 1.00 93.80  ? 459 ARG D NH2 1 
ATOM   17630 N N   . ARG D 1 460 ? 174.845 127.903 135.236 1.00 106.31 ? 460 ARG D N   1 
ATOM   17631 C CA  . ARG D 1 460 ? 175.409 129.277 135.462 1.00 104.45 ? 460 ARG D CA  1 
ATOM   17632 C C   . ARG D 1 460 ? 175.173 130.277 134.323 1.00 105.98 ? 460 ARG D C   1 
ATOM   17633 O O   . ARG D 1 460 ? 174.732 131.401 134.629 1.00 105.26 ? 460 ARG D O   1 
ATOM   17634 C CB  . ARG D 1 460 ? 176.887 129.040 135.786 1.00 100.75 ? 460 ARG D CB  1 
ATOM   17635 C CG  . ARG D 1 460 ? 177.716 130.274 136.136 1.00 101.96 ? 460 ARG D CG  1 
ATOM   17636 C CD  . ARG D 1 460 ? 179.139 129.839 136.502 1.00 103.99 ? 460 ARG D CD  1 
ATOM   17637 N NE  . ARG D 1 460 ? 179.957 129.519 135.318 1.00 104.96 ? 460 ARG D NE  1 
ATOM   17638 C CZ  . ARG D 1 460 ? 180.138 128.292 134.843 1.00 103.30 ? 460 ARG D CZ  1 
ATOM   17639 N NH1 . ARG D 1 460 ? 180.890 128.100 133.773 1.00 101.34 ? 460 ARG D NH1 1 
ATOM   17640 N NH2 . ARG D 1 460 ? 179.572 127.260 135.444 1.00 100.69 ? 460 ARG D NH2 1 
ATOM   17641 N N   . LEU D 1 461 ? 175.441 129.904 133.077 1.00 103.82 ? 461 LEU D N   1 
ATOM   17642 C CA  . LEU D 1 461 ? 175.374 130.821 131.927 1.00 105.55 ? 461 LEU D CA  1 
ATOM   17643 C C   . LEU D 1 461 ? 173.945 131.283 131.584 1.00 105.51 ? 461 LEU D C   1 
ATOM   17644 O O   . LEU D 1 461 ? 173.769 132.329 130.960 1.00 100.63 ? 461 LEU D O   1 
ATOM   17645 C CB  . LEU D 1 461 ? 176.031 130.161 130.704 1.00 105.57 ? 461 LEU D CB  1 
ATOM   17646 C CG  . LEU D 1 461 ? 177.510 129.769 130.877 1.00 106.68 ? 461 LEU D CG  1 
ATOM   17647 C CD1 . LEU D 1 461 ? 178.039 129.190 129.572 1.00 102.12 ? 461 LEU D CD1 1 
ATOM   17648 C CD2 . LEU D 1 461 ? 178.397 130.947 131.261 1.00 106.34 ? 461 LEU D CD2 1 
ATOM   17649 N N   . PHE D 1 462 ? 172.936 130.501 131.966 1.00 105.49 ? 462 PHE D N   1 
ATOM   17650 C CA  . PHE D 1 462 ? 171.523 130.703 131.631 1.00 104.20 ? 462 PHE D CA  1 
ATOM   17651 C C   . PHE D 1 462 ? 170.668 130.524 132.890 1.00 102.01 ? 462 PHE D C   1 
ATOM   17652 O O   . PHE D 1 462 ? 169.629 129.859 132.883 1.00 102.33 ? 462 PHE D O   1 
ATOM   17653 C CB  . PHE D 1 462 ? 171.121 129.770 130.478 1.00 100.36 ? 462 PHE D CB  1 
ATOM   17654 C CG  . PHE D 1 462 ? 171.908 129.986 129.201 1.00 101.27 ? 462 PHE D CG  1 
ATOM   17655 C CD1 . PHE D 1 462 ? 171.581 131.049 128.343 1.00 99.05  ? 462 PHE D CD1 1 
ATOM   17656 C CD2 . PHE D 1 462 ? 173.009 129.167 128.901 1.00 103.01 ? 462 PHE D CD2 1 
ATOM   17657 C CE1 . PHE D 1 462 ? 172.362 131.306 127.205 1.00 100.28 ? 462 PHE D CE1 1 
ATOM   17658 C CE2 . PHE D 1 462 ? 173.794 129.423 127.766 1.00 105.40 ? 462 PHE D CE2 1 
ATOM   17659 C CZ  . PHE D 1 462 ? 173.474 130.499 126.923 1.00 102.49 ? 462 PHE D CZ  1 
ATOM   17660 N N   . ILE D 1 463 ? 171.150 131.060 134.008 1.00 106.69 ? 463 ILE D N   1 
ATOM   17661 C CA  . ILE D 1 463 ? 170.683 130.674 135.340 1.00 111.86 ? 463 ILE D CA  1 
ATOM   17662 C C   . ILE D 1 463 ? 169.212 131.044 135.569 1.00 114.75 ? 463 ILE D C   1 
ATOM   17663 O O   . ILE D 1 463 ? 168.442 130.202 136.020 1.00 112.69 ? 463 ILE D O   1 
ATOM   17664 C CB  . ILE D 1 463 ? 171.662 131.210 136.402 1.00 110.98 ? 463 ILE D CB  1 
ATOM   17665 C CG1 . ILE D 1 463 ? 171.400 130.536 137.758 1.00 110.93 ? 463 ILE D CG1 1 
ATOM   17666 C CG2 . ILE D 1 463 ? 171.636 132.740 136.525 1.00 110.68 ? 463 ILE D CG2 1 
ATOM   17667 C CD1 . ILE D 1 463 ? 172.477 130.812 138.803 1.00 109.15 ? 463 ILE D CD1 1 
ATOM   17668 N N   . TRP D 1 464 ? 168.780 132.232 135.134 1.00 113.54 ? 464 TRP D N   1 
ATOM   17669 C CA  . TRP D 1 464 ? 167.380 132.658 135.197 1.00 111.95 ? 464 TRP D CA  1 
ATOM   17670 C C   . TRP D 1 464 ? 166.461 131.796 134.328 1.00 112.02 ? 464 TRP D C   1 
ATOM   17671 O O   . TRP D 1 464 ? 165.391 131.375 134.765 1.00 112.46 ? 464 TRP D O   1 
ATOM   17672 C CB  . TRP D 1 464 ? 167.294 134.115 134.755 1.00 108.39 ? 464 TRP D CB  1 
ATOM   17673 N N   . ILE D 1 465 ? 166.897 131.438 133.118 1.00 106.82 ? 465 ILE D N   1 
ATOM   17674 C CA  . ILE D 1 465 ? 166.175 130.514 132.224 1.00 107.23 ? 465 ILE D CA  1 
ATOM   17675 C C   . ILE D 1 465 ? 166.030 129.130 132.871 1.00 104.67 ? 465 ILE D C   1 
ATOM   17676 O O   . ILE D 1 465 ? 165.014 128.459 132.739 1.00 107.47 ? 465 ILE D O   1 
ATOM   17677 C CB  . ILE D 1 465 ? 166.866 130.400 130.846 1.00 105.94 ? 465 ILE D CB  1 
ATOM   17678 C CG1 . ILE D 1 465 ? 167.188 131.788 130.256 1.00 102.54 ? 465 ILE D CG1 1 
ATOM   17679 C CG2 . ILE D 1 465 ? 165.979 129.588 129.899 1.00 100.67 ? 465 ILE D CG2 1 
ATOM   17680 C CD1 . ILE D 1 465 ? 167.819 131.738 128.867 1.00 102.05 ? 465 ILE D CD1 1 
ATOM   17681 N N   . SER D 1 466 ? 167.031 128.726 133.641 1.00 106.16 ? 466 SER D N   1 
ATOM   17682 C CA  . SER D 1 466 ? 167.053 127.451 134.351 1.00 112.64 ? 466 SER D CA  1 
ATOM   17683 C C   . SER D 1 466 ? 166.275 127.448 135.679 1.00 114.22 ? 466 SER D C   1 
ATOM   17684 O O   . SER D 1 466 ? 166.292 126.431 136.372 1.00 114.79 ? 466 SER D O   1 
ATOM   17685 C CB  . SER D 1 466 ? 168.504 127.023 134.538 1.00 111.27 ? 466 SER D CB  1 
ATOM   17686 O OG  . SER D 1 466 ? 169.143 127.004 133.274 1.00 111.10 ? 466 SER D OG  1 
ATOM   17687 N N   . PHE D 1 467 ? 165.564 128.529 136.039 1.00 115.98 ? 467 PHE D N   1 
ATOM   17688 C CA  . PHE D 1 467 ? 164.616 128.539 137.162 1.00 116.11 ? 467 PHE D CA  1 
ATOM   17689 C C   . PHE D 1 467 ? 163.279 129.262 136.904 1.00 116.59 ? 467 PHE D C   1 
ATOM   17690 O O   . PHE D 1 467 ? 162.377 129.136 137.725 1.00 117.59 ? 467 PHE D O   1 
ATOM   17691 C CB  . PHE D 1 467 ? 165.299 129.027 138.451 1.00 113.79 ? 467 PHE D CB  1 
ATOM   17692 C CG  . PHE D 1 467 ? 165.781 130.470 138.511 1.00 115.52 ? 467 PHE D CG  1 
ATOM   17693 C CD1 . PHE D 1 467 ? 164.870 131.544 138.484 1.00 114.44 ? 467 PHE D CD1 1 
ATOM   17694 C CD2 . PHE D 1 467 ? 167.145 130.742 138.730 1.00 114.61 ? 467 PHE D CD2 1 
ATOM   17695 C CE1 . PHE D 1 467 ? 165.316 132.860 138.669 1.00 115.95 ? 467 PHE D CE1 1 
ATOM   17696 C CE2 . PHE D 1 467 ? 167.589 132.058 138.931 1.00 113.31 ? 467 PHE D CE2 1 
ATOM   17697 C CZ  . PHE D 1 467 ? 166.676 133.122 138.901 1.00 114.49 ? 467 PHE D CZ  1 
ATOM   17698 N N   . MET D 1 468 ? 163.102 129.996 135.798 1.00 113.30 ? 468 MET D N   1 
ATOM   17699 C CA  . MET D 1 468 ? 161.894 130.806 135.541 1.00 113.33 ? 468 MET D CA  1 
ATOM   17700 C C   . MET D 1 468 ? 160.579 130.013 135.625 1.00 113.27 ? 468 MET D C   1 
ATOM   17701 O O   . MET D 1 468 ? 159.630 130.450 136.271 1.00 110.54 ? 468 MET D O   1 
ATOM   17702 C CB  . MET D 1 468 ? 162.007 131.535 134.186 1.00 113.12 ? 468 MET D CB  1 
ATOM   17703 C CG  . MET D 1 468 ? 162.433 130.644 133.008 1.00 112.44 ? 468 MET D CG  1 
ATOM   17704 S SD  . MET D 1 468 ? 162.406 131.378 131.346 1.00 118.64 ? 468 MET D SD  1 
ATOM   17705 C CE  . MET D 1 468 ? 163.294 132.941 131.592 1.00 110.66 ? 468 MET D CE  1 
ATOM   17706 N N   . ASP D 1 469 ? 160.535 128.825 135.020 1.00 106.55 ? 469 ASP D N   1 
ATOM   17707 C CA  . ASP D 1 469 ? 159.451 127.846 135.180 1.00 103.84 ? 469 ASP D CA  1 
ATOM   17708 C C   . ASP D 1 469 ? 159.752 126.823 136.290 1.00 102.04 ? 469 ASP D C   1 
ATOM   17709 O O   . ASP D 1 469 ? 158.850 126.337 136.964 1.00 102.81 ? 469 ASP D O   1 
ATOM   17710 C CB  . ASP D 1 469 ? 159.218 127.129 133.841 1.00 102.41 ? 469 ASP D CB  1 
ATOM   17711 C CG  . ASP D 1 469 ? 160.449 126.452 133.213 1.00 101.15 ? 469 ASP D CG  1 
ATOM   17712 O OD1 . ASP D 1 469 ? 161.526 126.378 133.848 1.00 101.33 ? 469 ASP D OD1 1 
ATOM   17713 O OD2 . ASP D 1 469 ? 160.323 126.003 132.057 1.00 101.95 ? 469 ASP D OD2 1 
ATOM   17714 N N   . SER D 1 470 ? 161.029 126.506 136.479 1.00 89.84  ? 470 SER D N   1 
ATOM   17715 C CA  . SER D 1 470 ? 161.567 125.465 137.344 1.00 86.55  ? 470 SER D CA  1 
ATOM   17716 C C   . SER D 1 470 ? 161.861 126.000 138.745 1.00 87.84  ? 470 SER D C   1 
ATOM   17717 O O   . SER D 1 470 ? 162.969 125.876 139.266 1.00 86.90  ? 470 SER D O   1 
ATOM   17718 C CB  . SER D 1 470 ? 162.796 124.851 136.669 1.00 89.15  ? 470 SER D CB  1 
ATOM   17719 O OG  . SER D 1 470 ? 162.447 124.351 135.390 1.00 96.00  ? 470 SER D OG  1 
ATOM   17720 N N   . TYR D 1 471 ? 160.857 126.608 139.375 1.00 78.52  ? 471 TYR D N   1 
ATOM   17721 C CA  . TYR D 1 471 ? 160.971 127.233 140.692 1.00 63.54  ? 471 TYR D CA  1 
ATOM   17722 C C   . TYR D 1 471 ? 161.337 126.261 141.819 1.00 61.30  ? 471 TYR D C   1 
ATOM   17723 O O   . TYR D 1 471 ? 161.971 126.668 142.789 1.00 65.75  ? 471 TYR D O   1 
ATOM   17724 C CB  . TYR D 1 471 ? 159.677 127.986 141.005 1.00 68.23  ? 471 TYR D CB  1 
ATOM   17725 C CG  . TYR D 1 471 ? 158.427 127.143 141.181 1.00 75.56  ? 471 TYR D CG  1 
ATOM   17726 C CD1 . TYR D 1 471 ? 158.107 126.623 142.449 1.00 72.53  ? 471 TYR D CD1 1 
ATOM   17727 C CD2 . TYR D 1 471 ? 157.536 126.947 140.108 1.00 73.72  ? 471 TYR D CD2 1 
ATOM   17728 C CE1 . TYR D 1 471 ? 156.886 125.955 142.658 1.00 73.74  ? 471 TYR D CE1 1 
ATOM   17729 C CE2 . TYR D 1 471 ? 156.325 126.254 140.303 1.00 72.45  ? 471 TYR D CE2 1 
ATOM   17730 C CZ  . TYR D 1 471 ? 155.987 125.780 141.585 1.00 77.60  ? 471 TYR D CZ  1 
ATOM   17731 O OH  . TYR D 1 471 ? 154.795 125.168 141.806 1.00 71.10  ? 471 TYR D OH  1 
ATOM   17732 N N   . PHE D 1 472 ? 161.038 124.967 141.696 1.00 62.58  ? 472 PHE D N   1 
ATOM   17733 C CA  . PHE D 1 472 ? 161.464 123.960 142.669 1.00 57.22  ? 472 PHE D CA  1 
ATOM   17734 C C   . PHE D 1 472 ? 162.984 123.862 142.804 1.00 62.26  ? 472 PHE D C   1 
ATOM   17735 O O   . PHE D 1 472 ? 163.465 123.524 143.875 1.00 74.38  ? 472 PHE D O   1 
ATOM   17736 C CB  . PHE D 1 472 ? 160.889 122.588 142.323 1.00 52.47  ? 472 PHE D CB  1 
ATOM   17737 C CG  . PHE D 1 472 ? 159.412 122.437 142.598 1.00 59.78  ? 472 PHE D CG  1 
ATOM   17738 C CD1 . PHE D 1 472 ? 158.971 122.218 143.910 1.00 57.98  ? 472 PHE D CD1 1 
ATOM   17739 C CD2 . PHE D 1 472 ? 158.484 122.486 141.547 1.00 62.03  ? 472 PHE D CD2 1 
ATOM   17740 C CE1 . PHE D 1 472 ? 157.602 122.057 144.173 1.00 54.08  ? 472 PHE D CE1 1 
ATOM   17741 C CE2 . PHE D 1 472 ? 157.118 122.305 141.808 1.00 61.32  ? 472 PHE D CE2 1 
ATOM   17742 C CZ  . PHE D 1 472 ? 156.678 122.091 143.120 1.00 56.01  ? 472 PHE D CZ  1 
ATOM   17743 N N   . GLU D 1 473 ? 163.778 124.198 141.792 1.00 74.94  ? 473 GLU D N   1 
ATOM   17744 C CA  . GLU D 1 473 ? 165.237 124.115 141.926 1.00 70.37  ? 473 GLU D CA  1 
ATOM   17745 C C   . GLU D 1 473 ? 165.790 125.133 142.936 1.00 75.39  ? 473 GLU D C   1 
ATOM   17746 O O   . GLU D 1 473 ? 166.810 124.874 143.574 1.00 80.03  ? 473 GLU D O   1 
ATOM   17747 C CB  . GLU D 1 473 ? 165.901 124.238 140.544 1.00 74.11  ? 473 GLU D CB  1 
ATOM   17748 C CG  . GLU D 1 473 ? 165.426 123.174 139.536 1.00 79.50  ? 473 GLU D CG  1 
ATOM   17749 C CD  . GLU D 1 473 ? 165.495 121.733 140.069 1.00 88.41  ? 473 GLU D CD  1 
ATOM   17750 O OE1 . GLU D 1 473 ? 166.426 121.381 140.829 1.00 90.00  ? 473 GLU D OE1 1 
ATOM   17751 O OE2 . GLU D 1 473 ? 164.581 120.926 139.776 1.00 86.46  ? 473 GLU D OE2 1 
ATOM   17752 N N   . ILE D 1 474 ? 165.085 126.251 143.150 1.00 69.67  ? 474 ILE D N   1 
ATOM   17753 C CA  . ILE D 1 474 ? 165.344 127.219 144.223 1.00 61.40  ? 474 ILE D CA  1 
ATOM   17754 C C   . ILE D 1 474 ? 164.805 126.710 145.563 1.00 68.67  ? 474 ILE D C   1 
ATOM   17755 O O   . ILE D 1 474 ? 165.493 126.799 146.574 1.00 71.68  ? 474 ILE D O   1 
ATOM   17756 C CB  . ILE D 1 474 ? 164.717 128.586 143.877 1.00 67.07  ? 474 ILE D CB  1 
ATOM   17757 C CG1 . ILE D 1 474 ? 165.297 129.167 142.575 1.00 68.54  ? 474 ILE D CG1 1 
ATOM   17758 C CG2 . ILE D 1 474 ? 164.916 129.580 145.031 1.00 68.27  ? 474 ILE D CG2 1 
ATOM   17759 C CD1 . ILE D 1 474 ? 164.493 130.344 142.041 1.00 67.05  ? 474 ILE D CD1 1 
ATOM   17760 N N   . LEU D 1 475 ? 163.584 126.162 145.603 1.00 63.79  ? 475 LEU D N   1 
ATOM   17761 C CA  . LEU D 1 475 ? 162.957 125.684 146.838 1.00 57.95  ? 475 LEU D CA  1 
ATOM   17762 C C   . LEU D 1 475 ? 163.656 124.466 147.451 1.00 58.64  ? 475 LEU D C   1 
ATOM   17763 O O   . LEU D 1 475 ? 163.692 124.328 148.670 1.00 75.08  ? 475 LEU D O   1 
ATOM   17764 C CB  . LEU D 1 475 ? 161.478 125.361 146.602 1.00 52.18  ? 475 LEU D CB  1 
ATOM   17765 C CG  . LEU D 1 475 ? 160.593 126.499 146.084 1.00 53.83  ? 475 LEU D CG  1 
ATOM   17766 C CD1 . LEU D 1 475 ? 159.167 125.980 145.949 1.00 61.18  ? 475 LEU D CD1 1 
ATOM   17767 C CD2 . LEU D 1 475 ? 160.582 127.702 147.017 1.00 62.21  ? 475 LEU D CD2 1 
ATOM   17768 N N   . PHE D 1 476 ? 164.263 123.594 146.651 1.00 43.86  ? 476 PHE D N   1 
ATOM   17769 C CA  . PHE D 1 476 ? 165.144 122.538 147.146 1.00 47.58  ? 476 PHE D CA  1 
ATOM   17770 C C   . PHE D 1 476 ? 166.474 123.097 147.693 1.00 55.39  ? 476 PHE D C   1 
ATOM   17771 O O   . PHE D 1 476 ? 167.049 122.493 148.592 1.00 56.75  ? 476 PHE D O   1 
ATOM   17772 C CB  . PHE D 1 476 ? 165.364 121.489 146.047 1.00 50.15  ? 476 PHE D CB  1 
ATOM   17773 C CG  . PHE D 1 476 ? 164.329 120.375 145.985 1.00 52.49  ? 476 PHE D CG  1 
ATOM   17774 C CD1 . PHE D 1 476 ? 163.101 120.552 145.329 1.00 61.16  ? 476 PHE D CD1 1 
ATOM   17775 C CD2 . PHE D 1 476 ? 164.619 119.121 146.546 1.00 57.65  ? 476 PHE D CD2 1 
ATOM   17776 C CE1 . PHE D 1 476 ? 162.189 119.493 145.216 1.00 59.08  ? 476 PHE D CE1 1 
ATOM   17777 C CE2 . PHE D 1 476 ? 163.709 118.057 146.434 1.00 54.90  ? 476 PHE D CE2 1 
ATOM   17778 C CZ  . PHE D 1 476 ? 162.497 118.243 145.765 1.00 44.60  ? 476 PHE D CZ  1 
ATOM   17779 N N   . LEU D 1 477 ? 167.001 124.188 147.130 1.00 63.51  ? 477 LEU D N   1 
ATOM   17780 C CA  . LEU D 1 477 ? 168.232 124.813 147.613 1.00 62.57  ? 477 LEU D CA  1 
ATOM   17781 C C   . LEU D 1 477 ? 167.962 125.517 148.937 1.00 68.00  ? 477 LEU D C   1 
ATOM   17782 O O   . LEU D 1 477 ? 168.710 125.354 149.893 1.00 75.20  ? 477 LEU D O   1 
ATOM   17783 C CB  . LEU D 1 477 ? 168.782 125.788 146.555 1.00 65.39  ? 477 LEU D CB  1 
ATOM   17784 C CG  . LEU D 1 477 ? 170.040 126.554 146.998 1.00 63.61  ? 477 LEU D CG  1 
ATOM   17785 C CD1 . LEU D 1 477 ? 171.239 125.634 147.158 1.00 69.22  ? 477 LEU D CD1 1 
ATOM   17786 C CD2 . LEU D 1 477 ? 170.408 127.624 145.980 1.00 67.88  ? 477 LEU D CD2 1 
ATOM   17787 N N   . LEU D 1 478 ? 166.845 126.232 149.021 1.00 68.90  ? 478 LEU D N   1 
ATOM   17788 C CA  . LEU D 1 478 ? 166.370 126.890 150.224 1.00 63.58  ? 478 LEU D CA  1 
ATOM   17789 C C   . LEU D 1 478 ? 166.080 125.884 151.346 1.00 66.04  ? 478 LEU D C   1 
ATOM   17790 O O   . LEU D 1 478 ? 166.567 126.062 152.456 1.00 73.97  ? 478 LEU D O   1 
ATOM   17791 C CB  . LEU D 1 478 ? 165.149 127.731 149.830 1.00 61.06  ? 478 LEU D CB  1 
ATOM   17792 C CG  . LEU D 1 478 ? 164.542 128.551 150.969 1.00 70.78  ? 478 LEU D CG  1 
ATOM   17793 C CD1 . LEU D 1 478 ? 165.519 129.583 151.518 1.00 67.47  ? 478 LEU D CD1 1 
ATOM   17794 C CD2 . LEU D 1 478 ? 163.300 129.265 150.450 1.00 66.46  ? 478 LEU D CD2 1 
ATOM   17795 N N   . GLN D 1 479 ? 165.365 124.787 151.083 1.00 61.27  ? 479 GLN D N   1 
ATOM   17796 C CA  . GLN D 1 479 ? 165.131 123.751 152.097 1.00 60.88  ? 479 GLN D CA  1 
ATOM   17797 C C   . GLN D 1 479 ? 166.438 123.127 152.595 1.00 65.39  ? 479 GLN D C   1 
ATOM   17798 O O   . GLN D 1 479 ? 166.597 122.907 153.794 1.00 69.90  ? 479 GLN D O   1 
ATOM   17799 C CB  . GLN D 1 479 ? 164.187 122.682 151.539 1.00 59.59  ? 479 GLN D CB  1 
ATOM   17800 C CG  . GLN D 1 479 ? 163.520 121.817 152.615 1.00 59.32  ? 479 GLN D CG  1 
ATOM   17801 C CD  . GLN D 1 479 ? 164.254 120.559 153.084 1.00 65.46  ? 479 GLN D CD  1 
ATOM   17802 O OE1 . GLN D 1 479 ? 165.270 120.136 152.565 1.00 66.75  ? 479 GLN D OE1 1 
ATOM   17803 N NE2 . GLN D 1 479 ? 163.735 119.906 154.094 1.00 70.64  ? 479 GLN D NE2 1 
ATOM   17804 N N   . ALA D 1 480 ? 167.404 122.896 151.710 1.00 76.74  ? 480 ALA D N   1 
ATOM   17805 C CA  . ALA D 1 480 ? 168.704 122.360 152.072 1.00 69.31  ? 480 ALA D CA  1 
ATOM   17806 C C   . ALA D 1 480 ? 169.549 123.361 152.876 1.00 74.78  ? 480 ALA D C   1 
ATOM   17807 O O   . ALA D 1 480 ? 170.108 122.987 153.904 1.00 78.14  ? 480 ALA D O   1 
ATOM   17808 C CB  . ALA D 1 480 ? 169.403 121.930 150.793 1.00 70.98  ? 480 ALA D CB  1 
ATOM   17809 N N   . LEU D 1 481 ? 169.590 124.642 152.490 1.00 71.76  ? 481 LEU D N   1 
ATOM   17810 C CA  . LEU D 1 481 ? 170.255 125.691 153.269 1.00 72.24  ? 481 LEU D CA  1 
ATOM   17811 C C   . LEU D 1 481 ? 169.667 125.792 154.676 1.00 76.52  ? 481 LEU D C   1 
ATOM   17812 O O   . LEU D 1 481 ? 170.411 125.762 155.649 1.00 79.03  ? 481 LEU D O   1 
ATOM   17813 C CB  . LEU D 1 481 ? 170.137 127.053 152.563 1.00 73.51  ? 481 LEU D CB  1 
ATOM   17814 C CG  . LEU D 1 481 ? 171.116 127.268 151.402 1.00 82.94  ? 481 LEU D CG  1 
ATOM   17815 C CD1 . LEU D 1 481 ? 170.762 128.555 150.666 1.00 76.30  ? 481 LEU D CD1 1 
ATOM   17816 C CD2 . LEU D 1 481 ? 172.553 127.404 151.892 1.00 77.92  ? 481 LEU D CD2 1 
ATOM   17817 N N   . LEU D 1 482 ? 168.343 125.862 154.805 1.00 76.55  ? 482 LEU D N   1 
ATOM   17818 C CA  . LEU D 1 482 ? 167.660 125.943 156.096 1.00 72.27  ? 482 LEU D CA  1 
ATOM   17819 C C   . LEU D 1 482 ? 167.809 124.665 156.933 1.00 64.27  ? 482 LEU D C   1 
ATOM   17820 O O   . LEU D 1 482 ? 167.836 124.729 158.159 1.00 72.04  ? 482 LEU D O   1 
ATOM   17821 C CB  . LEU D 1 482 ? 166.183 126.240 155.839 1.00 71.58  ? 482 LEU D CB  1 
ATOM   17822 C CG  . LEU D 1 482 ? 165.890 127.618 155.235 1.00 67.91  ? 482 LEU D CG  1 
ATOM   17823 C CD1 . LEU D 1 482 ? 164.440 127.621 154.774 1.00 70.06  ? 482 LEU D CD1 1 
ATOM   17824 C CD2 . LEU D 1 482 ? 166.071 128.729 156.261 1.00 70.13  ? 482 LEU D CD2 1 
ATOM   17825 N N   . THR D 1 483 ? 167.961 123.501 156.308 1.00 68.00  ? 483 THR D N   1 
ATOM   17826 C CA  . THR D 1 483 ? 168.294 122.259 157.013 1.00 72.39  ? 483 THR D CA  1 
ATOM   17827 C C   . THR D 1 483 ? 169.714 122.300 157.573 1.00 73.24  ? 483 THR D C   1 
ATOM   17828 O O   . THR D 1 483 ? 169.927 121.987 158.734 1.00 75.21  ? 483 THR D O   1 
ATOM   17829 C CB  . THR D 1 483 ? 168.127 121.041 156.101 1.00 80.53  ? 483 THR D CB  1 
ATOM   17830 O OG1 . THR D 1 483 ? 166.798 120.986 155.664 1.00 80.48  ? 483 THR D OG1 1 
ATOM   17831 C CG2 . THR D 1 483 ? 168.423 119.735 156.822 1.00 71.64  ? 483 THR D CG2 1 
ATOM   17832 N N   . VAL D 1 484 ? 170.703 122.747 156.799 1.00 82.75  ? 484 VAL D N   1 
ATOM   17833 C CA  . VAL D 1 484 ? 172.076 122.893 157.300 1.00 81.58  ? 484 VAL D CA  1 
ATOM   17834 C C   . VAL D 1 484 ? 172.164 123.994 158.363 1.00 83.07  ? 484 VAL D C   1 
ATOM   17835 O O   . VAL D 1 484 ? 172.706 123.756 159.437 1.00 86.93  ? 484 VAL D O   1 
ATOM   17836 C CB  . VAL D 1 484 ? 173.061 123.111 156.138 1.00 86.26  ? 484 VAL D CB  1 
ATOM   17837 C CG1 . VAL D 1 484 ? 174.485 123.356 156.631 1.00 86.75  ? 484 VAL D CG1 1 
ATOM   17838 C CG2 . VAL D 1 484 ? 173.096 121.870 155.247 1.00 82.75  ? 484 VAL D CG2 1 
ATOM   17839 N N   . LEU D 1 485 ? 171.564 125.165 158.141 1.00 80.61  ? 485 LEU D N   1 
ATOM   17840 C CA  . LEU D 1 485 ? 171.507 126.244 159.129 1.00 80.94  ? 485 LEU D CA  1 
ATOM   17841 C C   . LEU D 1 485 ? 170.838 125.801 160.431 1.00 85.82  ? 485 LEU D C   1 
ATOM   17842 O O   . LEU D 1 485 ? 171.373 126.075 161.498 1.00 86.24  ? 485 LEU D O   1 
ATOM   17843 C CB  . LEU D 1 485 ? 170.756 127.457 158.557 1.00 84.50  ? 485 LEU D CB  1 
ATOM   17844 C CG  . LEU D 1 485 ? 171.542 128.244 157.502 1.00 90.64  ? 485 LEU D CG  1 
ATOM   17845 C CD1 . LEU D 1 485 ? 170.602 129.176 156.745 1.00 88.55  ? 485 LEU D CD1 1 
ATOM   17846 C CD2 . LEU D 1 485 ? 172.629 129.092 158.156 1.00 87.71  ? 485 LEU D CD2 1 
ATOM   17847 N N   . SER D 1 486 ? 169.703 125.102 160.391 1.00 86.92  ? 486 SER D N   1 
ATOM   17848 C CA  . SER D 1 486 ? 169.042 124.648 161.620 1.00 76.72  ? 486 SER D CA  1 
ATOM   17849 C C   . SER D 1 486 ? 169.884 123.632 162.390 1.00 78.28  ? 486 SER D C   1 
ATOM   17850 O O   . SER D 1 486 ? 169.997 123.758 163.602 1.00 90.53  ? 486 SER D O   1 
ATOM   17851 C CB  . SER D 1 486 ? 167.638 124.109 161.349 1.00 76.02  ? 486 SER D CB  1 
ATOM   17852 O OG  . SER D 1 486 ? 167.640 123.101 160.374 1.00 86.59  ? 486 SER D OG  1 
ATOM   17853 N N   . GLN D 1 487 ? 170.567 122.684 161.746 1.00 83.93  ? 487 GLN D N   1 
ATOM   17854 C CA  . GLN D 1 487 ? 171.489 121.816 162.485 1.00 85.26  ? 487 GLN D CA  1 
ATOM   17855 C C   . GLN D 1 487 ? 172.709 122.587 163.026 1.00 85.82  ? 487 GLN D C   1 
ATOM   17856 O O   . GLN D 1 487 ? 173.126 122.335 164.149 1.00 88.76  ? 487 GLN D O   1 
ATOM   17857 C CB  . GLN D 1 487 ? 171.911 120.611 161.637 1.00 88.33  ? 487 GLN D CB  1 
ATOM   17858 C CG  . GLN D 1 487 ? 170.753 119.721 161.164 1.00 86.78  ? 487 GLN D CG  1 
ATOM   17859 C CD  . GLN D 1 487 ? 169.770 119.305 162.248 1.00 89.38  ? 487 GLN D CD  1 
ATOM   17860 O OE1 . GLN D 1 487 ? 170.120 118.957 163.364 1.00 91.01  ? 487 GLN D OE1 1 
ATOM   17861 N NE2 . GLN D 1 487 ? 168.493 119.313 161.959 1.00 89.29  ? 487 GLN D NE2 1 
ATOM   17862 N N   . VAL D 1 488 ? 173.234 123.585 162.307 1.00 91.75  ? 488 VAL D N   1 
ATOM   17863 C CA  . VAL D 1 488 ? 174.296 124.478 162.804 1.00 93.52  ? 488 VAL D CA  1 
ATOM   17864 C C   . VAL D 1 488 ? 173.842 125.272 164.029 1.00 96.00  ? 488 VAL D C   1 
ATOM   17865 O O   . VAL D 1 488 ? 174.534 125.268 165.043 1.00 93.73  ? 488 VAL D O   1 
ATOM   17866 C CB  . VAL D 1 488 ? 174.808 125.392 161.676 1.00 93.22  ? 488 VAL D CB  1 
ATOM   17867 C CG1 . VAL D 1 488 ? 175.652 126.567 162.166 1.00 92.26  ? 488 VAL D CG1 1 
ATOM   17868 C CG2 . VAL D 1 488 ? 175.668 124.582 160.706 1.00 90.89  ? 488 VAL D CG2 1 
ATOM   17869 N N   . LEU D 1 489 ? 172.662 125.894 164.006 1.00 93.65  ? 489 LEU D N   1 
ATOM   17870 C CA  . LEU D 1 489 ? 172.107 126.581 165.172 1.00 87.51  ? 489 LEU D CA  1 
ATOM   17871 C C   . LEU D 1 489 ? 171.828 125.617 166.335 1.00 84.41  ? 489 LEU D C   1 
ATOM   17872 O O   . LEU D 1 489 ? 171.990 126.002 167.490 1.00 88.63  ? 489 LEU D O   1 
ATOM   17873 C CB  . LEU D 1 489 ? 170.834 127.355 164.794 1.00 89.70  ? 489 LEU D CB  1 
ATOM   17874 C CG  . LEU D 1 489 ? 171.005 128.538 163.827 1.00 88.76  ? 489 LEU D CG  1 
ATOM   17875 C CD1 . LEU D 1 489 ? 169.779 129.435 163.933 1.00 89.65  ? 489 LEU D CD1 1 
ATOM   17876 C CD2 . LEU D 1 489 ? 172.223 129.406 164.110 1.00 89.80  ? 489 LEU D CD2 1 
ATOM   17877 N N   . ARG D 1 490 ? 171.462 124.360 166.068 1.00 92.32  ? 490 ARG D N   1 
ATOM   17878 C CA  . ARG D 1 490 ? 171.297 123.334 167.108 1.00 95.76  ? 490 ARG D CA  1 
ATOM   17879 C C   . ARG D 1 490 ? 172.629 122.912 167.733 1.00 98.36  ? 490 ARG D C   1 
ATOM   17880 O O   . ARG D 1 490 ? 172.693 122.753 168.946 1.00 98.32  ? 490 ARG D O   1 
ATOM   17881 C CB  . ARG D 1 490 ? 170.545 122.129 166.536 1.00 91.66  ? 490 ARG D CB  1 
ATOM   17882 C CG  . ARG D 1 490 ? 170.009 121.212 167.633 1.00 93.05  ? 490 ARG D CG  1 
ATOM   17883 C CD  . ARG D 1 490 ? 169.443 119.925 167.044 1.00 96.95  ? 490 ARG D CD  1 
ATOM   17884 N NE  . ARG D 1 490 ? 170.519 119.032 166.569 1.00 102.94 ? 490 ARG D NE  1 
ATOM   17885 C CZ  . ARG D 1 490 ? 171.190 118.149 167.288 1.00 100.46 ? 490 ARG D CZ  1 
ATOM   17886 N NH1 . ARG D 1 490 ? 172.152 117.461 166.752 1.00 97.88  ? 490 ARG D NH1 1 
ATOM   17887 N NH2 . ARG D 1 490 ? 170.934 117.938 168.544 1.00 95.76  ? 490 ARG D NH2 1 
ATOM   17888 N N   . PHE D 1 491 ? 173.710 122.795 166.961 1.00 107.25 ? 491 PHE D N   1 
ATOM   17889 C CA  . PHE D 1 491 ? 175.063 122.602 167.505 1.00 102.87 ? 491 PHE D CA  1 
ATOM   17890 C C   . PHE D 1 491 ? 175.557 123.826 168.297 1.00 105.29 ? 491 PHE D C   1 
ATOM   17891 O O   . PHE D 1 491 ? 176.212 123.666 169.324 1.00 104.73 ? 491 PHE D O   1 
ATOM   17892 C CB  . PHE D 1 491 ? 176.046 122.254 166.377 1.00 99.98  ? 491 PHE D CB  1 
ATOM   17893 N N   . MET D 1 492 ? 175.182 125.044 167.897 1.00 109.59 ? 492 MET D N   1 
ATOM   17894 C CA  . MET D 1 492 ? 175.361 126.267 168.698 1.00 108.71 ? 492 MET D CA  1 
ATOM   17895 C C   . MET D 1 492 ? 174.429 126.351 169.925 1.00 108.22 ? 492 MET D C   1 
ATOM   17896 O O   . MET D 1 492 ? 174.575 127.248 170.750 1.00 105.26 ? 492 MET D O   1 
ATOM   17897 C CB  . MET D 1 492 ? 175.145 127.504 167.810 1.00 109.49 ? 492 MET D CB  1 
ATOM   17898 C CG  . MET D 1 492 ? 176.217 127.676 166.733 1.00 110.54 ? 492 MET D CG  1 
ATOM   17899 S SD  . MET D 1 492 ? 175.798 128.893 165.453 1.00 118.38 ? 492 MET D SD  1 
ATOM   17900 C CE  . MET D 1 492 ? 175.575 130.392 166.440 1.00 108.24 ? 492 MET D CE  1 
ATOM   17901 N N   . GLU D 1 493 ? 173.459 125.447 170.049 1.00 107.86 ? 493 GLU D N   1 
ATOM   17902 C CA  . GLU D 1 493 ? 172.430 125.412 171.091 1.00 106.51 ? 493 GLU D CA  1 
ATOM   17903 C C   . GLU D 1 493 ? 171.531 126.657 171.198 1.00 107.51 ? 493 GLU D C   1 
ATOM   17904 O O   . GLU D 1 493 ? 170.838 126.822 172.200 1.00 104.24 ? 493 GLU D O   1 
ATOM   17905 C CB  . GLU D 1 493 ? 173.061 125.026 172.428 1.00 102.15 ? 493 GLU D CB  1 
ATOM   17906 N N   . THR D 1 494 ? 171.501 127.537 170.188 1.00 107.39 ? 494 THR D N   1 
ATOM   17907 C CA  . THR D 1 494 ? 170.582 128.690 170.173 1.00 105.79 ? 494 THR D CA  1 
ATOM   17908 C C   . THR D 1 494 ? 169.172 128.258 169.778 1.00 104.04 ? 494 THR D C   1 
ATOM   17909 O O   . THR D 1 494 ? 168.972 127.544 168.798 1.00 104.39 ? 494 THR D O   1 
ATOM   17910 C CB  . THR D 1 494 ? 171.087 129.852 169.305 1.00 103.90 ? 494 THR D CB  1 
ATOM   17911 O OG1 . THR D 1 494 ? 170.181 130.929 169.378 1.00 100.79 ? 494 THR D OG1 1 
ATOM   17912 C CG2 . THR D 1 494 ? 171.238 129.545 167.825 1.00 103.17 ? 494 THR D CG2 1 
ATOM   17913 N N   . GLU D 1 495 ? 168.164 128.680 170.536 1.00 105.44 ? 495 GLU D N   1 
ATOM   17914 C CA  . GLU D 1 495 ? 166.793 128.169 170.417 1.00 106.45 ? 495 GLU D CA  1 
ATOM   17915 C C   . GLU D 1 495 ? 166.097 128.561 169.104 1.00 107.61 ? 495 GLU D C   1 
ATOM   17916 O O   . GLU D 1 495 ? 165.130 127.921 168.698 1.00 109.11 ? 495 GLU D O   1 
ATOM   17917 C CB  . GLU D 1 495 ? 165.972 128.604 171.639 1.00 102.70 ? 495 GLU D CB  1 
ATOM   17918 N N   . TRP D 1 496 ? 166.637 129.545 168.381 1.00 99.76  ? 496 TRP D N   1 
ATOM   17919 C CA  . TRP D 1 496 ? 166.241 129.873 167.009 1.00 97.49  ? 496 TRP D CA  1 
ATOM   17920 C C   . TRP D 1 496 ? 166.517 128.756 165.991 1.00 99.32  ? 496 TRP D C   1 
ATOM   17921 O O   . TRP D 1 496 ? 166.072 128.861 164.850 1.00 96.98  ? 496 TRP D O   1 
ATOM   17922 C CB  . TRP D 1 496 ? 166.900 131.189 166.589 1.00 94.98  ? 496 TRP D CB  1 
ATOM   17923 C CG  . TRP D 1 496 ? 166.285 132.395 167.226 1.00 103.23 ? 496 TRP D CG  1 
ATOM   17924 C CD1 . TRP D 1 496 ? 166.761 133.057 168.301 1.00 100.44 ? 496 TRP D CD1 1 
ATOM   17925 C CD2 . TRP D 1 496 ? 165.041 133.069 166.859 1.00 109.18 ? 496 TRP D CD2 1 
ATOM   17926 N NE1 . TRP D 1 496 ? 165.897 134.080 168.635 1.00 99.22  ? 496 TRP D NE1 1 
ATOM   17927 C CE2 . TRP D 1 496 ? 164.812 134.126 167.787 1.00 103.51 ? 496 TRP D CE2 1 
ATOM   17928 C CE3 . TRP D 1 496 ? 164.090 132.902 165.831 1.00 105.22 ? 496 TRP D CE3 1 
ATOM   17929 C CZ2 . TRP D 1 496 ? 163.683 134.950 167.718 1.00 98.13  ? 496 TRP D CZ2 1 
ATOM   17930 C CZ3 . TRP D 1 496 ? 162.950 133.726 165.750 1.00 99.23  ? 496 TRP D CZ3 1 
ATOM   17931 C CH2 . TRP D 1 496 ? 162.743 134.744 166.694 1.00 97.38  ? 496 TRP D CH2 1 
ATOM   17932 N N   . TYR D 1 497 ? 167.175 127.653 166.367 1.00 94.58  ? 497 TYR D N   1 
ATOM   17933 C CA  . TYR D 1 497 ? 167.228 126.469 165.511 1.00 90.36  ? 497 TYR D CA  1 
ATOM   17934 C C   . TYR D 1 497 ? 165.834 125.904 165.226 1.00 92.98  ? 497 TYR D C   1 
ATOM   17935 O O   . TYR D 1 497 ? 165.600 125.436 164.113 1.00 100.88 ? 497 TYR D O   1 
ATOM   17936 C CB  . TYR D 1 497 ? 168.135 125.385 166.110 1.00 89.65  ? 497 TYR D CB  1 
ATOM   17937 C CG  . TYR D 1 497 ? 167.457 124.364 167.000 1.00 90.64  ? 497 TYR D CG  1 
ATOM   17938 C CD1 . TYR D 1 497 ? 166.789 123.260 166.434 1.00 85.98  ? 497 TYR D CD1 1 
ATOM   17939 C CD2 . TYR D 1 497 ? 167.491 124.517 168.394 1.00 93.44  ? 497 TYR D CD2 1 
ATOM   17940 C CE1 . TYR D 1 497 ? 166.117 122.339 167.258 1.00 88.42  ? 497 TYR D CE1 1 
ATOM   17941 C CE2 . TYR D 1 497 ? 166.839 123.591 169.220 1.00 95.63  ? 497 TYR D CE2 1 
ATOM   17942 C CZ  . TYR D 1 497 ? 166.138 122.510 168.656 1.00 97.16  ? 497 TYR D CZ  1 
ATOM   17943 O OH  . TYR D 1 497 ? 165.504 121.634 169.474 1.00 97.91  ? 497 TYR D OH  1 
ATOM   17944 N N   . LEU D 1 498 ? 164.893 125.940 166.177 1.00 77.40  ? 498 LEU D N   1 
ATOM   17945 C CA  . LEU D 1 498 ? 163.596 125.280 166.008 1.00 79.30  ? 498 LEU D CA  1 
ATOM   17946 C C   . LEU D 1 498 ? 162.703 125.936 164.942 1.00 80.36  ? 498 LEU D C   1 
ATOM   17947 O O   . LEU D 1 498 ? 162.215 125.209 164.083 1.00 84.67  ? 498 LEU D O   1 
ATOM   17948 C CB  . LEU D 1 498 ? 162.888 125.106 167.359 1.00 76.11  ? 498 LEU D CB  1 
ATOM   17949 C CG  . LEU D 1 498 ? 161.589 124.292 167.252 1.00 76.53  ? 498 LEU D CG  1 
ATOM   17950 C CD1 . LEU D 1 498 ? 161.838 122.844 166.838 1.00 74.23  ? 498 LEU D CD1 1 
ATOM   17951 C CD2 . LEU D 1 498 ? 160.870 124.280 168.591 1.00 80.25  ? 498 LEU D CD2 1 
ATOM   17952 N N   . PRO D 1 499 ? 162.510 127.266 164.894 1.00 77.12  ? 499 PRO D N   1 
ATOM   17953 C CA  . PRO D 1 499 ? 161.759 127.884 163.803 1.00 77.13  ? 499 PRO D CA  1 
ATOM   17954 C C   . PRO D 1 499 ? 162.406 127.719 162.414 1.00 79.13  ? 499 PRO D C   1 
ATOM   17955 O O   . PRO D 1 499 ? 161.689 127.701 161.420 1.00 73.14  ? 499 PRO D O   1 
ATOM   17956 C CB  . PRO D 1 499 ? 161.562 129.344 164.217 1.00 73.78  ? 499 PRO D CB  1 
ATOM   17957 C CG  . PRO D 1 499 ? 162.654 129.602 165.242 1.00 76.72  ? 499 PRO D CG  1 
ATOM   17958 C CD  . PRO D 1 499 ? 162.806 128.250 165.921 1.00 77.67  ? 499 PRO D CD  1 
ATOM   17959 N N   . LEU D 1 500 ? 163.726 127.516 162.302 1.00 80.90  ? 500 LEU D N   1 
ATOM   17960 C CA  . LEU D 1 500 ? 164.362 127.132 161.032 1.00 75.15  ? 500 LEU D CA  1 
ATOM   17961 C C   . LEU D 1 500 ? 164.121 125.661 160.680 1.00 73.29  ? 500 LEU D C   1 
ATOM   17962 O O   . LEU D 1 500 ? 163.873 125.340 159.517 1.00 84.41  ? 500 LEU D O   1 
ATOM   17963 C CB  . LEU D 1 500 ? 165.876 127.391 161.066 1.00 76.01  ? 500 LEU D CB  1 
ATOM   17964 C CG  . LEU D 1 500 ? 166.347 128.844 161.173 1.00 75.82  ? 500 LEU D CG  1 
ATOM   17965 C CD1 . LEU D 1 500 ? 167.855 128.863 160.942 1.00 81.98  ? 500 LEU D CD1 1 
ATOM   17966 C CD2 . LEU D 1 500 ? 165.727 129.758 160.124 1.00 69.27  ? 500 LEU D CD2 1 
ATOM   17967 N N   . LEU D 1 501 ? 164.172 124.755 161.659 1.00 63.90  ? 501 LEU D N   1 
ATOM   17968 C CA  . LEU D 1 501 ? 163.870 123.337 161.440 1.00 69.74  ? 501 LEU D CA  1 
ATOM   17969 C C   . LEU D 1 501 ? 162.418 123.167 160.988 1.00 71.58  ? 501 LEU D C   1 
ATOM   17970 O O   . LEU D 1 501 ? 162.125 122.455 160.040 1.00 81.07  ? 501 LEU D O   1 
ATOM   17971 C CB  . LEU D 1 501 ? 164.156 122.546 162.728 1.00 70.50  ? 501 LEU D CB  1 
ATOM   17972 C CG  . LEU D 1 501 ? 163.921 121.033 162.589 1.00 68.73  ? 501 LEU D CG  1 
ATOM   17973 C CD1 . LEU D 1 501 ? 165.010 120.389 161.741 1.00 73.45  ? 501 LEU D CD1 1 
ATOM   17974 C CD2 . LEU D 1 501 ? 163.947 120.370 163.963 1.00 72.32  ? 501 LEU D CD2 1 
ATOM   17975 N N   . VAL D 1 502 ? 161.498 123.881 161.616 1.00 70.79  ? 502 VAL D N   1 
ATOM   17976 C CA  . VAL D 1 502 ? 160.077 123.858 161.275 1.00 70.10  ? 502 VAL D CA  1 
ATOM   17977 C C   . VAL D 1 502 ? 159.790 124.517 159.921 1.00 68.54  ? 502 VAL D C   1 
ATOM   17978 O O   . VAL D 1 502 ? 158.999 123.991 159.150 1.00 75.63  ? 502 VAL D O   1 
ATOM   17979 C CB  . VAL D 1 502 ? 159.295 124.476 162.438 1.00 74.86  ? 502 VAL D CB  1 
ATOM   17980 C CG1 . VAL D 1 502 ? 157.851 124.758 162.067 1.00 72.92  ? 502 VAL D CG1 1 
ATOM   17981 C CG2 . VAL D 1 502 ? 159.294 123.487 163.611 1.00 66.06  ? 502 VAL D CG2 1 
ATOM   17982 N N   . LEU D 1 503 ? 160.463 125.606 159.546 1.00 73.77  ? 503 LEU D N   1 
ATOM   17983 C CA  . LEU D 1 503 ? 160.335 126.168 158.199 1.00 76.85  ? 503 LEU D CA  1 
ATOM   17984 C C   . LEU D 1 503 ? 160.836 125.194 157.121 1.00 72.81  ? 503 LEU D C   1 
ATOM   17985 O O   . LEU D 1 503 ? 160.174 124.993 156.105 1.00 73.91  ? 503 LEU D O   1 
ATOM   17986 C CB  . LEU D 1 503 ? 161.072 127.517 158.144 1.00 72.50  ? 503 LEU D CB  1 
ATOM   17987 C CG  . LEU D 1 503 ? 161.046 128.186 156.760 1.00 77.59  ? 503 LEU D CG  1 
ATOM   17988 C CD1 . LEU D 1 503 ? 159.630 128.495 156.277 1.00 77.23  ? 503 LEU D CD1 1 
ATOM   17989 C CD2 . LEU D 1 503 ? 161.830 129.491 156.813 1.00 76.72  ? 503 LEU D CD2 1 
ATOM   17990 N N   . SER D 1 504 ? 161.985 124.556 157.339 1.00 68.80  ? 504 SER D N   1 
ATOM   17991 C CA  . SER D 1 504 ? 162.526 123.556 156.415 1.00 63.24  ? 504 SER D CA  1 
ATOM   17992 C C   . SER D 1 504 ? 161.736 122.245 156.406 1.00 65.76  ? 504 SER D C   1 
ATOM   17993 O O   . SER D 1 504 ? 161.733 121.562 155.388 1.00 79.83  ? 504 SER D O   1 
ATOM   17994 C CB  . SER D 1 504 ? 164.010 123.325 156.669 1.00 66.12  ? 504 SER D CB  1 
ATOM   17995 O OG  . SER D 1 504 ? 164.291 123.062 158.013 1.00 73.89  ? 504 SER D OG  1 
ATOM   17996 N N   . LEU D 1 505 ? 160.972 121.924 157.449 1.00 60.10  ? 505 LEU D N   1 
ATOM   17997 C CA  . LEU D 1 505 ? 159.969 120.858 157.432 1.00 58.43  ? 505 LEU D CA  1 
ATOM   17998 C C   . LEU D 1 505 ? 158.768 121.208 156.545 1.00 58.36  ? 505 LEU D C   1 
ATOM   17999 O O   . LEU D 1 505 ? 158.349 120.375 155.752 1.00 65.37  ? 505 LEU D O   1 
ATOM   18000 C CB  . LEU D 1 505 ? 159.550 120.581 158.882 1.00 66.73  ? 505 LEU D CB  1 
ATOM   18001 C CG  . LEU D 1 505 ? 158.411 119.574 159.079 1.00 61.78  ? 505 LEU D CG  1 
ATOM   18002 C CD1 . LEU D 1 505 ? 158.863 118.145 158.832 1.00 64.97  ? 505 LEU D CD1 1 
ATOM   18003 C CD2 . LEU D 1 505 ? 157.928 119.691 160.518 1.00 61.00  ? 505 LEU D CD2 1 
ATOM   18004 N N   . VAL D 1 506 ? 158.240 122.435 156.620 1.00 65.39  ? 506 VAL D N   1 
ATOM   18005 C CA  . VAL D 1 506 ? 157.154 122.896 155.738 1.00 58.30  ? 506 VAL D CA  1 
ATOM   18006 C C   . VAL D 1 506 ? 157.611 122.886 154.290 1.00 66.68  ? 506 VAL D C   1 
ATOM   18007 O O   . VAL D 1 506 ? 157.017 122.191 153.477 1.00 71.39  ? 506 VAL D O   1 
ATOM   18008 C CB  . VAL D 1 506 ? 156.638 124.297 156.096 1.00 55.72  ? 506 VAL D CB  1 
ATOM   18009 C CG1 . VAL D 1 506 ? 155.617 124.801 155.083 1.00 62.78  ? 506 VAL D CG1 1 
ATOM   18010 C CG2 . VAL D 1 506 ? 155.953 124.302 157.448 1.00 56.67  ? 506 VAL D CG2 1 
ATOM   18011 N N   . LEU D 1 507 ? 158.701 123.589 153.963 1.00 66.50  ? 507 LEU D N   1 
ATOM   18012 C CA  . LEU D 1 507 ? 159.282 123.556 152.620 1.00 53.00  ? 507 LEU D CA  1 
ATOM   18013 C C   . LEU D 1 507 ? 159.557 122.126 152.171 1.00 53.75  ? 507 LEU D C   1 
ATOM   18014 O O   . LEU D 1 507 ? 159.299 121.791 151.028 1.00 72.93  ? 507 LEU D O   1 
ATOM   18015 C CB  . LEU D 1 507 ? 160.589 124.354 152.599 1.00 61.02  ? 507 LEU D CB  1 
ATOM   18016 C CG  . LEU D 1 507 ? 160.374 125.829 152.262 1.00 64.60  ? 507 LEU D CG  1 
ATOM   18017 C CD1 . LEU D 1 507 ? 161.616 126.617 152.646 1.00 63.46  ? 507 LEU D CD1 1 
ATOM   18018 C CD2 . LEU D 1 507 ? 160.134 126.013 150.767 1.00 60.24  ? 507 LEU D CD2 1 
ATOM   18019 N N   . GLY D 1 508 ? 160.025 121.265 153.064 1.00 43.90  ? 508 GLY D N   1 
ATOM   18020 C CA  . GLY D 1 508 ? 160.272 119.870 152.770 1.00 50.38  ? 508 GLY D CA  1 
ATOM   18021 C C   . GLY D 1 508 ? 159.058 119.138 152.216 1.00 48.00  ? 508 GLY D C   1 
ATOM   18022 O O   . GLY D 1 508 ? 159.187 118.452 151.210 1.00 62.85  ? 508 GLY D O   1 
ATOM   18023 N N   . TRP D 1 509 ? 157.881 119.309 152.813 1.00 57.66  ? 509 TRP D N   1 
ATOM   18024 C CA  . TRP D 1 509 ? 156.642 118.709 152.315 1.00 50.25  ? 509 TRP D CA  1 
ATOM   18025 C C   . TRP D 1 509 ? 156.074 119.448 151.108 1.00 52.50  ? 509 TRP D C   1 
ATOM   18026 O O   . TRP D 1 509 ? 155.602 118.803 150.187 1.00 56.92  ? 509 TRP D O   1 
ATOM   18027 C CB  . TRP D 1 509 ? 155.611 118.609 153.441 1.00 60.27  ? 509 TRP D CB  1 
ATOM   18028 C CG  . TRP D 1 509 ? 155.887 117.508 154.416 1.00 58.87  ? 509 TRP D CG  1 
ATOM   18029 C CD1 . TRP D 1 509 ? 156.450 117.648 155.632 1.00 51.25  ? 509 TRP D CD1 1 
ATOM   18030 C CD2 . TRP D 1 509 ? 155.675 116.074 154.244 1.00 66.24  ? 509 TRP D CD2 1 
ATOM   18031 N NE1 . TRP D 1 509 ? 156.651 116.406 156.192 1.00 55.67  ? 509 TRP D NE1 1 
ATOM   18032 C CE2 . TRP D 1 509 ? 156.226 115.399 155.368 1.00 65.99  ? 509 TRP D CE2 1 
ATOM   18033 C CE3 . TRP D 1 509 ? 155.090 115.265 153.250 1.00 65.03  ? 509 TRP D CE3 1 
ATOM   18034 C CZ2 . TRP D 1 509 ? 156.258 114.002 155.475 1.00 62.51  ? 509 TRP D CZ2 1 
ATOM   18035 C CZ3 . TRP D 1 509 ? 155.111 113.857 153.350 1.00 69.21  ? 509 TRP D CZ3 1 
ATOM   18036 C CH2 . TRP D 1 509 ? 155.708 113.222 154.450 1.00 64.60  ? 509 TRP D CH2 1 
ATOM   18037 N N   . LEU D 1 510 ? 156.167 120.775 151.031 1.00 65.02  ? 510 LEU D N   1 
ATOM   18038 C CA  . LEU D 1 510 ? 155.768 121.517 149.828 1.00 60.58  ? 510 LEU D CA  1 
ATOM   18039 C C   . LEU D 1 510 ? 156.585 121.089 148.605 1.00 62.65  ? 510 LEU D C   1 
ATOM   18040 O O   . LEU D 1 510 ? 156.034 120.865 147.535 1.00 71.09  ? 510 LEU D O   1 
ATOM   18041 C CB  . LEU D 1 510 ? 155.897 123.031 150.060 1.00 57.51  ? 510 LEU D CB  1 
ATOM   18042 C CG  . LEU D 1 510 ? 155.002 123.610 151.163 1.00 61.49  ? 510 LEU D CG  1 
ATOM   18043 C CD1 . LEU D 1 510 ? 155.215 125.114 151.248 1.00 56.78  ? 510 LEU D CD1 1 
ATOM   18044 C CD2 . LEU D 1 510 ? 153.535 123.343 150.912 1.00 57.27  ? 510 LEU D CD2 1 
ATOM   18045 N N   . ASN D 1 511 ? 157.887 120.876 148.767 1.00 58.81  ? 511 ASN D N   1 
ATOM   18046 C CA  . ASN D 1 511 ? 158.777 120.340 147.746 1.00 50.23  ? 511 ASN D CA  1 
ATOM   18047 C C   . ASN D 1 511 ? 158.391 118.936 147.289 1.00 49.70  ? 511 ASN D C   1 
ATOM   18048 O O   . ASN D 1 511 ? 158.736 118.554 146.184 1.00 61.09  ? 511 ASN D O   1 
ATOM   18049 C CB  . ASN D 1 511 ? 160.203 120.324 148.296 1.00 47.42  ? 511 ASN D CB  1 
ATOM   18050 C CG  . ASN D 1 511 ? 160.852 121.679 148.369 1.00 55.68  ? 511 ASN D CG  1 
ATOM   18051 O OD1 . ASN D 1 511 ? 160.325 122.674 147.912 1.00 61.27  ? 511 ASN D OD1 1 
ATOM   18052 N ND2 . ASN D 1 511 ? 162.038 121.757 148.916 1.00 54.25  ? 511 ASN D ND2 1 
ATOM   18053 N N   . LEU D 1 512 ? 157.638 118.170 148.074 1.00 57.24  ? 512 LEU D N   1 
ATOM   18054 C CA  . LEU D 1 512 ? 157.139 116.855 147.677 1.00 54.61  ? 512 LEU D CA  1 
ATOM   18055 C C   . LEU D 1 512 ? 156.162 116.957 146.501 1.00 49.26  ? 512 LEU D C   1 
ATOM   18056 O O   . LEU D 1 512 ? 156.013 116.016 145.732 1.00 51.47  ? 512 LEU D O   1 
ATOM   18057 C CB  . LEU D 1 512 ? 156.469 116.203 148.894 1.00 54.57  ? 512 LEU D CB  1 
ATOM   18058 C CG  . LEU D 1 512 ? 156.341 114.684 148.811 1.00 55.95  ? 512 LEU D CG  1 
ATOM   18059 C CD1 . LEU D 1 512 ? 157.706 114.017 148.912 1.00 59.62  ? 512 LEU D CD1 1 
ATOM   18060 C CD2 . LEU D 1 512 ? 155.515 114.187 149.978 1.00 57.00  ? 512 LEU D CD2 1 
ATOM   18061 N N   . LEU D 1 513 ? 155.550 118.121 146.285 1.00 49.64  ? 513 LEU D N   1 
ATOM   18062 C CA  . LEU D 1 513 ? 154.710 118.376 145.120 1.00 53.10  ? 513 LEU D CA  1 
ATOM   18063 C C   . LEU D 1 513 ? 155.501 118.454 143.820 1.00 51.95  ? 513 LEU D C   1 
ATOM   18064 O O   . LEU D 1 513 ? 154.889 118.339 142.759 1.00 57.43  ? 513 LEU D O   1 
ATOM   18065 C CB  . LEU D 1 513 ? 153.891 119.657 145.317 1.00 55.32  ? 513 LEU D CB  1 
ATOM   18066 C CG  . LEU D 1 513 ? 152.915 119.571 146.487 1.00 49.68  ? 513 LEU D CG  1 
ATOM   18067 C CD1 . LEU D 1 513 ? 152.413 120.959 146.834 1.00 49.03  ? 513 LEU D CD1 1 
ATOM   18068 C CD2 . LEU D 1 513 ? 151.732 118.669 146.162 1.00 42.30  ? 513 LEU D CD2 1 
ATOM   18069 N N   . TYR D 1 514 ? 156.834 118.554 143.824 1.00 56.24  ? 514 TYR D N   1 
ATOM   18070 C CA  . TYR D 1 514 ? 157.623 118.450 142.594 1.00 41.60  ? 514 TYR D CA  1 
ATOM   18071 C C   . TYR D 1 514 ? 157.293 117.162 141.841 1.00 50.20  ? 514 TYR D C   1 
ATOM   18072 O O   . TYR D 1 514 ? 156.992 117.190 140.650 1.00 67.15  ? 514 TYR D O   1 
ATOM   18073 C CB  . TYR D 1 514 ? 159.117 118.522 142.919 1.00 43.06  ? 514 TYR D CB  1 
ATOM   18074 C CG  . TYR D 1 514 ? 160.019 118.154 141.759 1.00 37.37  ? 514 TYR D CG  1 
ATOM   18075 C CD1 . TYR D 1 514 ? 160.296 119.081 140.746 1.00 51.27  ? 514 TYR D CD1 1 
ATOM   18076 C CD2 . TYR D 1 514 ? 160.553 116.861 141.675 1.00 59.11  ? 514 TYR D CD2 1 
ATOM   18077 C CE1 . TYR D 1 514 ? 161.086 118.706 139.646 1.00 65.13  ? 514 TYR D CE1 1 
ATOM   18078 C CE2 . TYR D 1 514 ? 161.326 116.469 140.572 1.00 56.16  ? 514 TYR D CE2 1 
ATOM   18079 C CZ  . TYR D 1 514 ? 161.591 117.394 139.546 1.00 66.79  ? 514 TYR D CZ  1 
ATOM   18080 O OH  . TYR D 1 514 ? 162.329 117.028 138.469 1.00 67.85  ? 514 TYR D OH  1 
ATOM   18081 N N   . TYR D 1 515 ? 157.262 116.036 142.551 1.00 56.41  ? 515 TYR D N   1 
ATOM   18082 C CA  . TYR D 1 515 ? 157.142 114.704 141.965 1.00 46.15  ? 515 TYR D CA  1 
ATOM   18083 C C   . TYR D 1 515 ? 155.752 114.381 141.420 1.00 43.90  ? 515 TYR D C   1 
ATOM   18084 O O   . TYR D 1 515 ? 155.573 113.354 140.777 1.00 55.09  ? 515 TYR D O   1 
ATOM   18085 C CB  . TYR D 1 515 ? 157.611 113.669 142.984 1.00 42.25  ? 515 TYR D CB  1 
ATOM   18086 C CG  . TYR D 1 515 ? 159.035 113.889 143.445 1.00 46.11  ? 515 TYR D CG  1 
ATOM   18087 C CD1 . TYR D 1 515 ? 160.104 113.426 142.659 1.00 55.54  ? 515 TYR D CD1 1 
ATOM   18088 C CD2 . TYR D 1 515 ? 159.294 114.565 144.650 1.00 48.88  ? 515 TYR D CD2 1 
ATOM   18089 C CE1 . TYR D 1 515 ? 161.428 113.626 143.078 1.00 54.03  ? 515 TYR D CE1 1 
ATOM   18090 C CE2 . TYR D 1 515 ? 160.614 114.755 145.077 1.00 46.58  ? 515 TYR D CE2 1 
ATOM   18091 C CZ  . TYR D 1 515 ? 161.684 114.287 144.293 1.00 55.69  ? 515 TYR D CZ  1 
ATOM   18092 O OH  . TYR D 1 515 ? 162.953 114.475 144.717 1.00 65.29  ? 515 TYR D OH  1 
ATOM   18093 N N   . THR D 1 516 ? 154.766 115.266 141.574 1.00 53.88  ? 516 THR D N   1 
ATOM   18094 C CA  . THR D 1 516 ? 153.443 115.096 140.947 1.00 44.85  ? 516 THR D CA  1 
ATOM   18095 C C   . THR D 1 516 ? 153.514 115.029 139.421 1.00 57.44  ? 516 THR D C   1 
ATOM   18096 O O   . THR D 1 516 ? 152.623 114.444 138.815 1.00 65.38  ? 516 THR D O   1 
ATOM   18097 C CB  . THR D 1 516 ? 152.454 116.193 141.347 1.00 57.15  ? 516 THR D CB  1 
ATOM   18098 O OG1 . THR D 1 516 ? 152.930 117.473 141.017 1.00 68.73  ? 516 THR D OG1 1 
ATOM   18099 C CG2 . THR D 1 516 ? 152.098 116.162 142.820 1.00 52.56  ? 516 THR D CG2 1 
ATOM   18100 N N   . ARG D 1 517 ? 154.578 115.547 138.792 1.00 64.92  ? 517 ARG D N   1 
ATOM   18101 C CA  . ARG D 1 517 ? 154.847 115.468 137.343 1.00 59.58  ? 517 ARG D CA  1 
ATOM   18102 C C   . ARG D 1 517 ? 155.180 114.076 136.817 1.00 62.85  ? 517 ARG D C   1 
ATOM   18103 O O   . ARG D 1 517 ? 155.234 113.901 135.606 1.00 69.45  ? 517 ARG D O   1 
ATOM   18104 C CB  . ARG D 1 517 ? 155.935 116.478 136.947 1.00 54.02  ? 517 ARG D CB  1 
ATOM   18105 C CG  . ARG D 1 517 ? 157.345 116.097 137.427 1.00 48.83  ? 517 ARG D CG  1 
ATOM   18106 C CD  . ARG D 1 517 ? 158.342 117.242 137.275 1.00 49.93  ? 517 ARG D CD  1 
ATOM   18107 N NE  . ARG D 1 517 ? 157.937 118.393 138.097 1.00 57.68  ? 517 ARG D NE  1 
ATOM   18108 C CZ  . ARG D 1 517 ? 158.215 119.659 137.882 1.00 60.14  ? 517 ARG D CZ  1 
ATOM   18109 N NH1 . ARG D 1 517 ? 157.610 120.580 138.560 1.00 53.59  ? 517 ARG D NH1 1 
ATOM   18110 N NH2 . ARG D 1 517 ? 159.079 120.035 136.990 1.00 62.20  ? 517 ARG D NH2 1 
ATOM   18111 N N   . GLY D 1 518 ? 155.402 113.087 137.676 1.00 67.57  ? 518 GLY D N   1 
ATOM   18112 C CA  . GLY D 1 518 ? 155.739 111.734 137.240 1.00 64.26  ? 518 GLY D CA  1 
ATOM   18113 C C   . GLY D 1 518 ? 154.583 110.978 136.593 1.00 69.59  ? 518 GLY D C   1 
ATOM   18114 O O   . GLY D 1 518 ? 154.818 110.080 135.793 1.00 75.00  ? 518 GLY D O   1 
ATOM   18115 N N   . PHE D 1 519 ? 153.338 111.350 136.888 1.00 64.80  ? 519 PHE D N   1 
ATOM   18116 C CA  . PHE D 1 519 ? 152.134 110.762 136.303 1.00 70.20  ? 519 PHE D CA  1 
ATOM   18117 C C   . PHE D 1 519 ? 151.360 111.805 135.517 1.00 73.44  ? 519 PHE D C   1 
ATOM   18118 O O   . PHE D 1 519 ? 151.287 112.957 135.931 1.00 73.56  ? 519 PHE D O   1 
ATOM   18119 C CB  . PHE D 1 519 ? 151.236 110.167 137.392 1.00 75.42  ? 519 PHE D CB  1 
ATOM   18120 C CG  . PHE D 1 519 ? 151.894 109.143 138.287 1.00 78.05  ? 519 PHE D CG  1 
ATOM   18121 C CD1 . PHE D 1 519 ? 152.145 107.849 137.800 1.00 73.08  ? 519 PHE D CD1 1 
ATOM   18122 C CD2 . PHE D 1 519 ? 152.251 109.476 139.604 1.00 73.34  ? 519 PHE D CD2 1 
ATOM   18123 C CE1 . PHE D 1 519 ? 152.755 106.892 138.624 1.00 69.27  ? 519 PHE D CE1 1 
ATOM   18124 C CE2 . PHE D 1 519 ? 152.857 108.516 140.430 1.00 75.92  ? 519 PHE D CE2 1 
ATOM   18125 C CZ  . PHE D 1 519 ? 153.109 107.226 139.940 1.00 70.39  ? 519 PHE D CZ  1 
ATOM   18126 N N   . GLN D 1 520 ? 150.728 111.405 134.417 1.00 83.46  ? 520 GLN D N   1 
ATOM   18127 C CA  . GLN D 1 520 ? 149.959 112.320 133.580 1.00 80.69  ? 520 GLN D CA  1 
ATOM   18128 C C   . GLN D 1 520 ? 148.845 113.027 134.350 1.00 77.12  ? 520 GLN D C   1 
ATOM   18129 O O   . GLN D 1 520 ? 148.707 114.236 134.244 1.00 74.90  ? 520 GLN D O   1 
ATOM   18130 C CB  . GLN D 1 520 ? 149.408 111.561 132.366 1.00 80.75  ? 520 GLN D CB  1 
ATOM   18131 C CG  . GLN D 1 520 ? 148.694 112.518 131.400 1.00 81.23  ? 520 GLN D CG  1 
ATOM   18132 C CD  . GLN D 1 520 ? 148.457 111.956 130.003 1.00 85.42  ? 520 GLN D CD  1 
ATOM   18133 O OE1 . GLN D 1 520 ? 149.049 110.982 129.565 1.00 86.40  ? 520 GLN D OE1 1 
ATOM   18134 N NE2 . GLN D 1 520 ? 147.579 112.560 129.236 1.00 83.35  ? 520 GLN D NE2 1 
ATOM   18135 N N   . HIS D 1 521 ? 148.060 112.312 135.154 1.00 85.96  ? 521 HIS D N   1 
ATOM   18136 C CA  . HIS D 1 521 ? 146.877 112.896 135.785 1.00 88.21  ? 521 HIS D CA  1 
ATOM   18137 C C   . HIS D 1 521 ? 147.217 113.934 136.841 1.00 90.82  ? 521 HIS D C   1 
ATOM   18138 O O   . HIS D 1 521 ? 146.747 115.062 136.732 1.00 91.83  ? 521 HIS D O   1 
ATOM   18139 C CB  . HIS D 1 521 ? 145.932 111.793 136.268 1.00 86.83  ? 521 HIS D CB  1 
ATOM   18140 C CG  . HIS D 1 521 ? 145.283 111.144 135.074 1.00 94.75  ? 521 HIS D CG  1 
ATOM   18141 N ND1 . HIS D 1 521 ? 144.287 111.735 134.296 1.00 89.69  ? 521 HIS D ND1 1 
ATOM   18142 C CD2 . HIS D 1 521 ? 145.692 109.993 134.470 1.00 94.10  ? 521 HIS D CD2 1 
ATOM   18143 C CE1 . HIS D 1 521 ? 144.110 110.919 133.246 1.00 90.45  ? 521 HIS D CE1 1 
ATOM   18144 N NE2 . HIS D 1 521 ? 144.935 109.865 133.328 1.00 91.76  ? 521 HIS D NE2 1 
ATOM   18145 N N   . THR D 1 522 ? 148.072 113.631 137.814 1.00 82.26  ? 522 THR D N   1 
ATOM   18146 C CA  . THR D 1 522 ? 148.556 114.634 138.777 1.00 73.99  ? 522 THR D CA  1 
ATOM   18147 C C   . THR D 1 522 ? 149.461 115.687 138.127 1.00 82.26  ? 522 THR D C   1 
ATOM   18148 O O   . THR D 1 522 ? 149.392 116.854 138.504 1.00 71.79  ? 522 THR D O   1 
ATOM   18149 C CB  . THR D 1 522 ? 149.290 113.966 139.946 1.00 65.54  ? 522 THR D CB  1 
ATOM   18150 O OG1 . THR D 1 522 ? 150.311 113.109 139.500 1.00 76.86  ? 522 THR D OG1 1 
ATOM   18151 C CG2 . THR D 1 522 ? 148.344 113.124 140.789 1.00 64.34  ? 522 THR D CG2 1 
ATOM   18152 N N   . GLY D 1 523 ? 150.267 115.309 137.130 1.00 83.56  ? 523 GLY D N   1 
ATOM   18153 C CA  . GLY D 1 523 ? 151.276 116.161 136.496 1.00 68.09  ? 523 GLY D CA  1 
ATOM   18154 C C   . GLY D 1 523 ? 150.715 117.200 135.540 1.00 73.13  ? 523 GLY D C   1 
ATOM   18155 O O   . GLY D 1 523 ? 151.221 118.312 135.484 1.00 76.54  ? 523 GLY D O   1 
ATOM   18156 N N   . ILE D 1 524 ? 149.625 116.883 134.847 1.00 79.24  ? 524 ILE D N   1 
ATOM   18157 C CA  . ILE D 1 524 ? 148.832 117.859 134.100 1.00 80.83  ? 524 ILE D CA  1 
ATOM   18158 C C   . ILE D 1 524 ? 148.032 118.763 135.044 1.00 85.77  ? 524 ILE D C   1 
ATOM   18159 O O   . ILE D 1 524 ? 147.932 119.956 134.785 1.00 82.02  ? 524 ILE D O   1 
ATOM   18160 C CB  . ILE D 1 524 ? 147.939 117.127 133.078 1.00 83.52  ? 524 ILE D CB  1 
ATOM   18161 C CG1 . ILE D 1 524 ? 148.847 116.659 131.925 1.00 77.39  ? 524 ILE D CG1 1 
ATOM   18162 C CG2 . ILE D 1 524 ? 146.796 118.003 132.571 1.00 84.18  ? 524 ILE D CG2 1 
ATOM   18163 C CD1 . ILE D 1 524 ? 148.120 115.911 130.814 1.00 78.40  ? 524 ILE D CD1 1 
ATOM   18164 N N   . TYR D 1 525 ? 147.503 118.264 136.164 1.00 83.84  ? 525 TYR D N   1 
ATOM   18165 C CA  . TYR D 1 525 ? 146.760 119.126 137.078 1.00 83.40  ? 525 TYR D CA  1 
ATOM   18166 C C   . TYR D 1 525 ? 147.652 120.153 137.778 1.00 82.40  ? 525 TYR D C   1 
ATOM   18167 O O   . TYR D 1 525 ? 147.301 121.327 137.836 1.00 81.65  ? 525 TYR D O   1 
ATOM   18168 C CB  . TYR D 1 525 ? 145.972 118.302 138.085 1.00 83.87  ? 525 TYR D CB  1 
ATOM   18169 C CG  . TYR D 1 525 ? 144.921 119.133 138.783 1.00 81.03  ? 525 TYR D CG  1 
ATOM   18170 C CD1 . TYR D 1 525 ? 143.814 119.592 138.050 1.00 79.24  ? 525 TYR D CD1 1 
ATOM   18171 C CD2 . TYR D 1 525 ? 145.084 119.507 140.129 1.00 80.51  ? 525 TYR D CD2 1 
ATOM   18172 C CE1 . TYR D 1 525 ? 142.865 120.431 138.658 1.00 83.94  ? 525 TYR D CE1 1 
ATOM   18173 C CE2 . TYR D 1 525 ? 144.125 120.332 140.744 1.00 83.04  ? 525 TYR D CE2 1 
ATOM   18174 C CZ  . TYR D 1 525 ? 143.015 120.797 140.007 1.00 82.24  ? 525 TYR D CZ  1 
ATOM   18175 O OH  . TYR D 1 525 ? 142.097 121.605 140.584 1.00 74.13  ? 525 TYR D OH  1 
ATOM   18176 N N   . SER D 1 526 ? 148.857 119.764 138.198 1.00 81.33  ? 526 SER D N   1 
ATOM   18177 C CA  . SER D 1 526 ? 149.872 120.707 138.682 1.00 82.45  ? 526 SER D CA  1 
ATOM   18178 C C   . SER D 1 526 ? 150.208 121.822 137.684 1.00 81.27  ? 526 SER D C   1 
ATOM   18179 O O   . SER D 1 526 ? 150.689 122.876 138.080 1.00 83.05  ? 526 SER D O   1 
ATOM   18180 C CB  . SER D 1 526 ? 151.146 119.951 139.062 1.00 85.48  ? 526 SER D CB  1 
ATOM   18181 O OG  . SER D 1 526 ? 150.884 119.125 140.177 1.00 82.43  ? 526 SER D OG  1 
ATOM   18182 N N   . VAL D 1 527 ? 149.917 121.625 136.397 1.00 88.33  ? 527 VAL D N   1 
ATOM   18183 C CA  . VAL D 1 527 ? 150.053 122.612 135.321 1.00 87.86  ? 527 VAL D CA  1 
ATOM   18184 C C   . VAL D 1 527 ? 148.753 123.382 135.044 1.00 90.09  ? 527 VAL D C   1 
ATOM   18185 O O   . VAL D 1 527 ? 148.806 124.560 134.705 1.00 89.88  ? 527 VAL D O   1 
ATOM   18186 C CB  . VAL D 1 527 ? 150.561 121.883 134.075 1.00 85.09  ? 527 VAL D CB  1 
ATOM   18187 C CG1 . VAL D 1 527 ? 150.525 122.740 132.827 1.00 86.41  ? 527 VAL D CG1 1 
ATOM   18188 C CG2 . VAL D 1 527 ? 152.008 121.436 134.260 1.00 85.01  ? 527 VAL D CG2 1 
ATOM   18189 N N   . MET D 1 528 ? 147.579 122.767 135.208 1.00 97.92  ? 528 MET D N   1 
ATOM   18190 C CA  . MET D 1 528 ? 146.285 123.461 135.115 1.00 97.18  ? 528 MET D CA  1 
ATOM   18191 C C   . MET D 1 528 ? 146.120 124.536 136.190 1.00 94.61  ? 528 MET D C   1 
ATOM   18192 O O   . MET D 1 528 ? 145.634 125.623 135.888 1.00 92.84  ? 528 MET D O   1 
ATOM   18193 C CB  . MET D 1 528 ? 145.124 122.474 135.265 1.00 96.35  ? 528 MET D CB  1 
ATOM   18194 C CG  . MET D 1 528 ? 144.937 121.553 134.061 1.00 99.60  ? 528 MET D CG  1 
ATOM   18195 S SD  . MET D 1 528 ? 143.700 120.249 134.306 1.00 108.41 ? 528 MET D SD  1 
ATOM   18196 C CE  . MET D 1 528 ? 142.225 121.240 134.640 1.00 94.89  ? 528 MET D CE  1 
ATOM   18197 N N   . ILE D 1 529 ? 146.512 124.195 137.416 1.00 95.56  ? 529 ILE D N   1 
ATOM   18198 C CA  . ILE D 1 529 ? 146.272 124.995 138.605 1.00 92.51  ? 529 ILE D CA  1 
ATOM   18199 C C   . ILE D 1 529 ? 147.199 126.222 138.675 1.00 92.75  ? 529 ILE D C   1 
ATOM   18200 O O   . ILE D 1 529 ? 146.701 127.339 138.773 1.00 91.37  ? 529 ILE D O   1 
ATOM   18201 C CB  . ILE D 1 529 ? 146.266 124.046 139.831 1.00 91.99  ? 529 ILE D CB  1 
ATOM   18202 C CG1 . ILE D 1 529 ? 145.510 124.656 141.022 1.00 90.78  ? 529 ILE D CG1 1 
ATOM   18203 C CG2 . ILE D 1 529 ? 147.661 123.579 140.270 1.00 90.26  ? 529 ILE D CG2 1 
ATOM   18204 C CD1 . ILE D 1 529 ? 144.936 123.615 141.977 1.00 89.15  ? 529 ILE D CD1 1 
ATOM   18205 N N   . GLN D 1 530 ? 148.525 126.070 138.587 1.00 97.92  ? 530 GLN D N   1 
ATOM   18206 C CA  . GLN D 1 530 ? 149.460 127.202 138.695 1.00 96.49  ? 530 GLN D CA  1 
ATOM   18207 C C   . GLN D 1 530 ? 149.465 128.050 137.415 1.00 94.61  ? 530 GLN D C   1 
ATOM   18208 O O   . GLN D 1 530 ? 149.680 127.515 136.331 1.00 94.03  ? 530 GLN D O   1 
ATOM   18209 C CB  . GLN D 1 530 ? 150.858 126.707 139.114 1.00 93.24  ? 530 GLN D CB  1 
ATOM   18210 C CG  . GLN D 1 530 ? 151.664 125.994 138.017 1.00 94.46  ? 530 GLN D CG  1 
ATOM   18211 C CD  . GLN D 1 530 ? 152.863 125.191 138.530 1.00 98.38  ? 530 GLN D CD  1 
ATOM   18212 O OE1 . GLN D 1 530 ? 153.092 125.004 139.720 1.00 99.03  ? 530 GLN D OE1 1 
ATOM   18213 N NE2 . GLN D 1 530 ? 153.718 124.726 137.652 1.00 97.52  ? 530 GLN D NE2 1 
ATOM   18214 N N   . LYS D 1 531 ? 149.204 129.364 137.515 1.00 91.25  ? 531 LYS D N   1 
ATOM   18215 C CA  . LYS D 1 531 ? 149.029 130.251 136.344 1.00 95.79  ? 531 LYS D CA  1 
ATOM   18216 C C   . LYS D 1 531 ? 149.216 131.750 136.640 1.00 99.98  ? 531 LYS D C   1 
ATOM   18217 O O   . LYS D 1 531 ? 149.713 132.126 137.701 1.00 92.48  ? 531 LYS D O   1 
ATOM   18218 C CB  . LYS D 1 531 ? 147.677 129.916 135.665 1.00 90.62  ? 531 LYS D CB  1 
ATOM   18219 C CG  . LYS D 1 531 ? 146.400 130.263 136.451 1.00 84.08  ? 531 LYS D CG  1 
ATOM   18220 C CD  . LYS D 1 531 ? 145.200 129.414 135.993 1.00 88.92  ? 531 LYS D CD  1 
ATOM   18221 C CE  . LYS D 1 531 ? 144.952 129.507 134.477 1.00 90.70  ? 531 LYS D CE  1 
ATOM   18222 N NZ  . LYS D 1 531 ? 143.975 128.498 133.997 1.00 83.80  ? 531 LYS D NZ  1 
ATOM   18223 N N   . VAL D 1 532 ? 148.762 132.594 135.702 1.00 108.16 ? 532 VAL D N   1 
ATOM   18224 C CA  . VAL D 1 532 ? 148.726 134.084 135.685 1.00 99.51  ? 532 VAL D CA  1 
ATOM   18225 C C   . VAL D 1 532 ? 148.192 134.730 136.975 1.00 95.06  ? 532 VAL D C   1 
ATOM   18226 O O   . VAL D 1 532 ? 148.508 135.877 137.278 1.00 96.47  ? 532 VAL D O   1 
ATOM   18227 C CB  . VAL D 1 532 ? 147.879 134.530 134.468 1.00 97.06  ? 532 VAL D CB  1 
ATOM   18228 C CG1 . VAL D 1 532 ? 147.479 136.003 134.461 1.00 93.95  ? 532 VAL D CG1 1 
ATOM   18229 C CG2 . VAL D 1 532 ? 148.637 134.259 133.161 1.00 96.78  ? 532 VAL D CG2 1 
ATOM   18230 N N   . ILE D 1 533 ? 147.460 133.985 137.795 1.00 90.50  ? 533 ILE D N   1 
ATOM   18231 C CA  . ILE D 1 533 ? 147.039 134.395 139.138 1.00 88.90  ? 533 ILE D CA  1 
ATOM   18232 C C   . ILE D 1 533 ? 148.235 134.832 140.005 1.00 90.60  ? 533 ILE D C   1 
ATOM   18233 O O   . ILE D 1 533 ? 148.122 135.812 140.734 1.00 93.35  ? 533 ILE D O   1 
ATOM   18234 C CB  . ILE D 1 533 ? 146.214 133.246 139.757 1.00 89.22  ? 533 ILE D CB  1 
ATOM   18235 C CG1 . ILE D 1 533 ? 144.902 133.080 138.958 1.00 92.45  ? 533 ILE D CG1 1 
ATOM   18236 C CG2 . ILE D 1 533 ? 145.903 133.486 141.240 1.00 90.34  ? 533 ILE D CG2 1 
ATOM   18237 C CD1 . ILE D 1 533 ? 144.188 131.755 139.199 1.00 92.90  ? 533 ILE D CD1 1 
ATOM   18238 N N   . LEU D 1 534 ? 149.414 134.206 139.880 1.00 92.52  ? 534 LEU D N   1 
ATOM   18239 C CA  . LEU D 1 534 ? 150.607 134.611 140.639 1.00 85.01  ? 534 LEU D CA  1 
ATOM   18240 C C   . LEU D 1 534 ? 151.136 136.004 140.260 1.00 84.45  ? 534 LEU D C   1 
ATOM   18241 O O   . LEU D 1 534 ? 151.698 136.698 141.106 1.00 84.27  ? 534 LEU D O   1 
ATOM   18242 C CB  . LEU D 1 534 ? 151.724 133.563 140.466 1.00 90.88  ? 534 LEU D CB  1 
ATOM   18243 C CG  . LEU D 1 534 ? 151.414 132.163 141.026 1.00 93.01  ? 534 LEU D CG  1 
ATOM   18244 C CD1 . LEU D 1 534 ? 152.575 131.225 140.715 1.00 86.83  ? 534 LEU D CD1 1 
ATOM   18245 C CD2 . LEU D 1 534 ? 151.201 132.165 142.536 1.00 88.11  ? 534 LEU D CD2 1 
ATOM   18246 N N   . ARG D 1 535 ? 150.855 136.432 139.013 1.00 95.69  ? 535 ARG D N   1 
ATOM   18247 C CA  . ARG D 1 535 ? 151.285 137.763 138.484 1.00 96.73  ? 535 ARG D CA  1 
ATOM   18248 C C   . ARG D 1 535 ? 150.368 138.868 138.996 1.00 94.38  ? 535 ARG D C   1 
ATOM   18249 O O   . ARG D 1 535 ? 150.887 139.921 139.414 1.00 91.59  ? 535 ARG D O   1 
ATOM   18250 C CB  . ARG D 1 535 ? 151.183 137.759 136.943 1.00 96.33  ? 535 ARG D CB  1 
ATOM   18251 C CG  . ARG D 1 535 ? 151.604 139.069 136.254 1.00 91.80  ? 535 ARG D CG  1 
ATOM   18252 C CD  . ARG D 1 535 ? 151.099 139.120 134.800 1.00 93.45  ? 535 ARG D CD  1 
ATOM   18253 N NE  . ARG D 1 535 ? 149.642 139.340 134.746 1.00 96.57  ? 535 ARG D NE  1 
ATOM   18254 C CZ  . ARG D 1 535 ? 148.920 139.382 133.633 1.00 96.76  ? 535 ARG D CZ  1 
ATOM   18255 N NH1 . ARG D 1 535 ? 147.616 139.587 133.700 1.00 92.71  ? 535 ARG D NH1 1 
ATOM   18256 N NH2 . ARG D 1 535 ? 149.502 139.215 132.458 1.00 93.94  ? 535 ARG D NH2 1 
ATOM   18257 N N   . ASP D 1 536 ? 149.060 138.632 138.964 1.00 92.54  ? 536 ASP D N   1 
ATOM   18258 C CA  . ASP D 1 536 ? 148.064 139.640 139.327 1.00 86.00  ? 536 ASP D CA  1 
ATOM   18259 C C   . ASP D 1 536 ? 147.770 139.731 140.818 1.00 86.46  ? 536 ASP D C   1 
ATOM   18260 O O   . ASP D 1 536 ? 147.528 140.827 141.312 1.00 93.57  ? 536 ASP D O   1 
ATOM   18261 C CB  . ASP D 1 536 ? 146.779 139.405 138.538 1.00 89.61  ? 536 ASP D CB  1 
ATOM   18262 C CG  . ASP D 1 536 ? 146.944 139.744 137.057 1.00 94.75  ? 536 ASP D CG  1 
ATOM   18263 O OD1 . ASP D 1 536 ? 147.948 140.392 136.680 1.00 97.83  ? 536 ASP D OD1 1 
ATOM   18264 O OD2 . ASP D 1 536 ? 146.079 139.373 136.243 1.00 94.88  ? 536 ASP D OD2 1 
ATOM   18265 N N   . LEU D 1 537 ? 147.870 138.646 141.585 1.00 85.98  ? 537 LEU D N   1 
ATOM   18266 C CA  . LEU D 1 537 ? 147.761 138.756 143.040 1.00 86.17  ? 537 LEU D CA  1 
ATOM   18267 C C   . LEU D 1 537 ? 148.873 139.612 143.649 1.00 86.73  ? 537 LEU D C   1 
ATOM   18268 O O   . LEU D 1 537 ? 148.609 140.380 144.564 1.00 91.76  ? 537 LEU D O   1 
ATOM   18269 C CB  . LEU D 1 537 ? 147.727 137.373 143.691 1.00 88.25  ? 537 LEU D CB  1 
ATOM   18270 C CG  . LEU D 1 537 ? 146.415 136.607 143.474 1.00 90.83  ? 537 LEU D CG  1 
ATOM   18271 C CD1 . LEU D 1 537 ? 146.519 135.318 144.269 1.00 87.14  ? 537 LEU D CD1 1 
ATOM   18272 C CD2 . LEU D 1 537 ? 145.182 137.359 143.972 1.00 88.73  ? 537 LEU D CD2 1 
ATOM   18273 N N   . LEU D 1 538 ? 150.087 139.579 143.103 1.00 83.58  ? 538 LEU D N   1 
ATOM   18274 C CA  . LEU D 1 538 ? 151.177 140.466 143.510 1.00 88.19  ? 538 LEU D CA  1 
ATOM   18275 C C   . LEU D 1 538 ? 150.912 141.945 143.159 1.00 84.60  ? 538 LEU D C   1 
ATOM   18276 O O   . LEU D 1 538 ? 151.505 142.841 143.754 1.00 84.06  ? 538 LEU D O   1 
ATOM   18277 C CB  . LEU D 1 538 ? 152.477 139.917 142.891 1.00 89.66  ? 538 LEU D CB  1 
ATOM   18278 C CG  . LEU D 1 538 ? 153.771 140.625 143.313 1.00 89.64  ? 538 LEU D CG  1 
ATOM   18279 C CD1 . LEU D 1 538 ? 154.004 140.548 144.818 1.00 84.51  ? 538 LEU D CD1 1 
ATOM   18280 C CD2 . LEU D 1 538 ? 154.962 139.972 142.621 1.00 87.53  ? 538 LEU D CD2 1 
ATOM   18281 N N   . ARG D 1 539 ? 149.951 142.193 142.248 1.00 79.33  ? 539 ARG D N   1 
ATOM   18282 C CA  . ARG D 1 539 ? 149.541 143.594 141.902 1.00 76.40  ? 539 ARG D CA  1 
ATOM   18283 C C   . ARG D 1 539 ? 148.401 143.997 142.852 1.00 79.54  ? 539 ARG D C   1 
ATOM   18284 O O   . ARG D 1 539 ? 148.465 145.120 143.390 1.00 84.10  ? 539 ARG D O   1 
ATOM   18285 C CB  . ARG D 1 539 ? 149.249 143.725 140.399 1.00 78.41  ? 539 ARG D CB  1 
ATOM   18286 C CG  . ARG D 1 539 ? 150.479 143.375 139.551 1.00 75.92  ? 539 ARG D CG  1 
ATOM   18287 C CD  . ARG D 1 539 ? 150.392 143.905 138.124 1.00 76.05  ? 539 ARG D CD  1 
ATOM   18288 N NE  . ARG D 1 539 ? 149.512 143.134 137.222 1.00 79.62  ? 539 ARG D NE  1 
ATOM   18289 C CZ  . ARG D 1 539 ? 149.232 143.472 135.969 1.00 78.59  ? 539 ARG D CZ  1 
ATOM   18290 N NH1 . ARG D 1 539 ? 148.429 142.712 135.243 1.00 76.30  ? 539 ARG D NH1 1 
ATOM   18291 N NH2 . ARG D 1 539 ? 149.751 144.568 135.445 1.00 79.19  ? 539 ARG D NH2 1 
ATOM   18292 N N   . PHE D 1 540 ? 147.412 143.126 143.060 1.00 81.83  ? 540 PHE D N   1 
ATOM   18293 C CA  . PHE D 1 540 ? 146.311 143.327 144.011 1.00 74.26  ? 540 PHE D CA  1 
ATOM   18294 C C   . PHE D 1 540 ? 146.816 143.522 145.439 1.00 76.00  ? 540 PHE D C   1 
ATOM   18295 O O   . PHE D 1 540 ? 146.275 144.350 146.159 1.00 74.84  ? 540 PHE D O   1 
ATOM   18296 C CB  . PHE D 1 540 ? 145.346 142.131 143.929 1.00 76.38  ? 540 PHE D CB  1 
ATOM   18297 C CG  . PHE D 1 540 ? 144.622 141.755 145.213 1.00 91.80  ? 540 PHE D CG  1 
ATOM   18298 C CD1 . PHE D 1 540 ? 143.494 142.480 145.642 1.00 85.68  ? 540 PHE D CD1 1 
ATOM   18299 C CD2 . PHE D 1 540 ? 145.080 140.665 145.981 1.00 87.27  ? 540 PHE D CD2 1 
ATOM   18300 C CE1 . PHE D 1 540 ? 142.844 142.122 146.841 1.00 78.52  ? 540 PHE D CE1 1 
ATOM   18301 C CE2 . PHE D 1 540 ? 144.440 140.317 147.176 1.00 79.01  ? 540 PHE D CE2 1 
ATOM   18302 C CZ  . PHE D 1 540 ? 143.318 141.057 147.606 1.00 80.15  ? 540 PHE D CZ  1 
ATOM   18303 N N   . LEU D 1 541 ? 147.884 142.829 145.827 1.00 74.81  ? 541 LEU D N   1 
ATOM   18304 C CA  . LEU D 1 541 ? 148.474 142.918 147.156 1.00 72.57  ? 541 LEU D CA  1 
ATOM   18305 C C   . LEU D 1 541 ? 148.938 144.343 147.492 1.00 67.71  ? 541 LEU D C   1 
ATOM   18306 O O   . LEU D 1 541 ? 148.790 144.771 148.625 1.00 75.75  ? 541 LEU D O   1 
ATOM   18307 C CB  . LEU D 1 541 ? 149.606 141.890 147.250 1.00 71.75  ? 541 LEU D CB  1 
ATOM   18308 C CG  . LEU D 1 541 ? 150.236 141.768 148.639 1.00 75.82  ? 541 LEU D CG  1 
ATOM   18309 C CD1 . LEU D 1 541 ? 149.253 141.182 149.648 1.00 72.14  ? 541 LEU D CD1 1 
ATOM   18310 C CD2 . LEU D 1 541 ? 151.460 140.869 148.565 1.00 76.85  ? 541 LEU D CD2 1 
ATOM   18311 N N   . LEU D 1 542 ? 149.423 145.121 146.524 1.00 56.79  ? 542 LEU D N   1 
ATOM   18312 C CA  . LEU D 1 542 ? 149.751 146.530 146.746 1.00 60.41  ? 542 LEU D CA  1 
ATOM   18313 C C   . LEU D 1 542 ? 148.508 147.359 147.100 1.00 61.80  ? 542 LEU D C   1 
ATOM   18314 O O   . LEU D 1 542 ? 148.532 148.143 148.043 1.00 64.97  ? 542 LEU D O   1 
ATOM   18315 C CB  . LEU D 1 542 ? 150.471 147.058 145.491 1.00 71.20  ? 542 LEU D CB  1 
ATOM   18316 C CG  . LEU D 1 542 ? 150.895 148.533 145.558 1.00 73.14  ? 542 LEU D CG  1 
ATOM   18317 C CD1 . LEU D 1 542 ? 151.910 148.806 146.666 1.00 67.64  ? 542 LEU D CD1 1 
ATOM   18318 C CD2 . LEU D 1 542 ? 151.531 148.924 144.234 1.00 60.03  ? 542 LEU D CD2 1 
ATOM   18319 N N   . VAL D 1 543 ? 147.395 147.154 146.393 1.00 66.63  ? 543 VAL D N   1 
ATOM   18320 C CA  . VAL D 1 543 ? 146.122 147.840 146.670 1.00 67.55  ? 543 VAL D CA  1 
ATOM   18321 C C   . VAL D 1 543 ? 145.542 147.401 148.015 1.00 62.46  ? 543 VAL D C   1 
ATOM   18322 O O   . VAL D 1 543 ? 145.181 148.236 148.837 1.00 59.96  ? 543 VAL D O   1 
ATOM   18323 C CB  . VAL D 1 543 ? 145.094 147.626 145.545 1.00 63.58  ? 543 VAL D CB  1 
ATOM   18324 C CG1 . VAL D 1 543 ? 143.902 148.564 145.712 1.00 55.67  ? 543 VAL D CG1 1 
ATOM   18325 C CG2 . VAL D 1 543 ? 145.688 147.894 144.162 1.00 61.64  ? 543 VAL D CG2 1 
ATOM   18326 N N   . TYR D 1 544 ? 145.527 146.094 148.286 1.00 68.60  ? 544 TYR D N   1 
ATOM   18327 C CA  . TYR D 1 544 ? 145.057 145.533 149.542 1.00 61.87  ? 544 TYR D CA  1 
ATOM   18328 C C   . TYR D 1 544 ? 145.885 145.979 150.753 1.00 61.11  ? 544 TYR D C   1 
ATOM   18329 O O   . TYR D 1 544 ? 145.309 146.276 151.793 1.00 65.28  ? 544 TYR D O   1 
ATOM   18330 C CB  . TYR D 1 544 ? 145.067 144.002 149.480 1.00 69.45  ? 544 TYR D CB  1 
ATOM   18331 C CG  . TYR D 1 544 ? 144.616 143.340 150.757 1.00 76.72  ? 544 TYR D CG  1 
ATOM   18332 C CD1 . TYR D 1 544 ? 145.515 143.060 151.774 1.00 75.45  ? 544 TYR D CD1 1 
ATOM   18333 C CD2 . TYR D 1 544 ? 143.286 143.011 150.961 1.00 72.08  ? 544 TYR D CD2 1 
ATOM   18334 C CE1 . TYR D 1 544 ? 145.107 142.459 152.953 1.00 74.41  ? 544 TYR D CE1 1 
ATOM   18335 C CE2 . TYR D 1 544 ? 142.862 142.411 152.135 1.00 66.53  ? 544 TYR D CE2 1 
ATOM   18336 C CZ  . TYR D 1 544 ? 143.775 142.133 153.135 1.00 75.48  ? 544 TYR D CZ  1 
ATOM   18337 O OH  . TYR D 1 544 ? 143.364 141.542 154.294 1.00 78.59  ? 544 TYR D OH  1 
ATOM   18338 N N   . LEU D 1 545 ? 147.213 146.079 150.649 1.00 60.97  ? 545 LEU D N   1 
ATOM   18339 C CA  . LEU D 1 545 ? 148.069 146.545 151.746 1.00 58.63  ? 545 LEU D CA  1 
ATOM   18340 C C   . LEU D 1 545 ? 148.025 148.060 151.974 1.00 54.60  ? 545 LEU D C   1 
ATOM   18341 O O   . LEU D 1 545 ? 148.179 148.486 153.113 1.00 55.11  ? 545 LEU D O   1 
ATOM   18342 C CB  . LEU D 1 545 ? 149.515 146.084 151.527 1.00 56.50  ? 545 LEU D CB  1 
ATOM   18343 C CG  . LEU D 1 545 ? 149.739 144.572 151.669 1.00 65.75  ? 545 LEU D CG  1 
ATOM   18344 C CD1 . LEU D 1 545 ? 151.203 144.272 151.387 1.00 63.24  ? 545 LEU D CD1 1 
ATOM   18345 C CD2 . LEU D 1 545 ? 149.404 144.046 153.058 1.00 66.35  ? 545 LEU D CD2 1 
ATOM   18346 N N   . VAL D 1 546 ? 147.773 148.893 150.963 1.00 65.29  ? 546 VAL D N   1 
ATOM   18347 C CA  . VAL D 1 546 ? 147.512 150.325 151.199 1.00 61.16  ? 546 VAL D CA  1 
ATOM   18348 C C   . VAL D 1 546 ? 146.168 150.529 151.892 1.00 68.30  ? 546 VAL D C   1 
ATOM   18349 O O   . VAL D 1 546 ? 146.087 151.337 152.814 1.00 65.70  ? 546 VAL D O   1 
ATOM   18350 C CB  . VAL D 1 546 ? 147.613 151.151 149.907 1.00 61.18  ? 546 VAL D CB  1 
ATOM   18351 C CG1 . VAL D 1 546 ? 147.167 152.596 150.125 1.00 57.53  ? 546 VAL D CG1 1 
ATOM   18352 C CG2 . VAL D 1 546 ? 149.062 151.200 149.419 1.00 65.16  ? 546 VAL D CG2 1 
ATOM   18353 N N   . PHE D 1 547 ? 145.128 149.768 151.533 1.00 77.33  ? 547 PHE D N   1 
ATOM   18354 C CA  . PHE D 1 547 ? 143.881 149.748 152.297 1.00 66.38  ? 547 PHE D CA  1 
ATOM   18355 C C   . PHE D 1 547 ? 144.137 149.272 153.728 1.00 68.87  ? 547 PHE D C   1 
ATOM   18356 O O   . PHE D 1 547 ? 143.838 149.990 154.676 1.00 77.65  ? 547 PHE D O   1 
ATOM   18357 C CB  . PHE D 1 547 ? 142.838 148.834 151.637 1.00 68.07  ? 547 PHE D CB  1 
ATOM   18358 C CG  . PHE D 1 547 ? 142.125 149.310 150.385 1.00 74.86  ? 547 PHE D CG  1 
ATOM   18359 C CD1 . PHE D 1 547 ? 142.525 150.446 149.660 1.00 71.03  ? 547 PHE D CD1 1 
ATOM   18360 C CD2 . PHE D 1 547 ? 141.004 148.579 149.950 1.00 75.46  ? 547 PHE D CD2 1 
ATOM   18361 C CE1 . PHE D 1 547 ? 141.793 150.864 148.538 1.00 73.22  ? 547 PHE D CE1 1 
ATOM   18362 C CE2 . PHE D 1 547 ? 140.288 148.989 148.817 1.00 77.28  ? 547 PHE D CE2 1 
ATOM   18363 C CZ  . PHE D 1 547 ? 140.673 150.133 148.112 1.00 70.36  ? 547 PHE D CZ  1 
ATOM   18364 N N   . LEU D 1 548 ? 144.719 148.089 153.907 1.00 62.91  ? 548 LEU D N   1 
ATOM   18365 C CA  . LEU D 1 548 ? 144.899 147.475 155.217 1.00 60.98  ? 548 LEU D CA  1 
ATOM   18366 C C   . LEU D 1 548 ? 145.733 148.343 156.163 1.00 64.14  ? 548 LEU D C   1 
ATOM   18367 O O   . LEU D 1 548 ? 145.295 148.607 157.275 1.00 72.05  ? 548 LEU D O   1 
ATOM   18368 C CB  . LEU D 1 548 ? 145.487 146.067 155.023 1.00 65.40  ? 548 LEU D CB  1 
ATOM   18369 C CG  . LEU D 1 548 ? 145.697 145.285 156.324 1.00 58.48  ? 548 LEU D CG  1 
ATOM   18370 C CD1 . LEU D 1 548 ? 144.376 145.004 157.012 1.00 64.99  ? 548 LEU D CD1 1 
ATOM   18371 C CD2 . LEU D 1 548 ? 146.363 143.953 156.030 1.00 61.73  ? 548 LEU D CD2 1 
ATOM   18372 N N   . PHE D 1 549 ? 146.897 148.840 155.744 1.00 67.92  ? 549 PHE D N   1 
ATOM   18373 C CA  . PHE D 1 549 ? 147.692 149.733 156.585 1.00 63.42  ? 549 PHE D CA  1 
ATOM   18374 C C   . PHE D 1 549 ? 147.007 151.090 156.796 1.00 67.26  ? 549 PHE D C   1 
ATOM   18375 O O   . PHE D 1 549 ? 146.971 151.574 157.921 1.00 63.99  ? 549 PHE D O   1 
ATOM   18376 C CB  . PHE D 1 549 ? 149.089 149.900 155.984 1.00 67.57  ? 549 PHE D CB  1 
ATOM   18377 C CG  . PHE D 1 549 ? 149.999 150.790 156.804 1.00 76.26  ? 549 PHE D CG  1 
ATOM   18378 C CD1 . PHE D 1 549 ? 150.607 150.283 157.967 1.00 78.84  ? 549 PHE D CD1 1 
ATOM   18379 C CD2 . PHE D 1 549 ? 150.235 152.126 156.427 1.00 69.40  ? 549 PHE D CD2 1 
ATOM   18380 C CE1 . PHE D 1 549 ? 151.447 151.101 158.742 1.00 71.76  ? 549 PHE D CE1 1 
ATOM   18381 C CE2 . PHE D 1 549 ? 151.073 152.940 157.205 1.00 70.30  ? 549 PHE D CE2 1 
ATOM   18382 C CZ  . PHE D 1 549 ? 151.679 152.431 158.361 1.00 70.00  ? 549 PHE D CZ  1 
ATOM   18383 N N   . GLY D 1 550 ? 146.409 151.684 155.760 1.00 72.70  ? 550 GLY D N   1 
ATOM   18384 C CA  . GLY D 1 550 ? 145.739 152.980 155.857 1.00 69.55  ? 550 GLY D CA  1 
ATOM   18385 C C   . GLY D 1 550 ? 144.595 152.996 156.869 1.00 74.92  ? 550 GLY D C   1 
ATOM   18386 O O   . GLY D 1 550 ? 144.476 153.945 157.642 1.00 74.15  ? 550 GLY D O   1 
ATOM   18387 N N   . PHE D 1 551 ? 143.787 151.933 156.912 1.00 63.50  ? 551 PHE D N   1 
ATOM   18388 C CA  . PHE D 1 551 ? 142.738 151.753 157.913 1.00 55.31  ? 551 PHE D CA  1 
ATOM   18389 C C   . PHE D 1 551 ? 143.278 151.281 159.274 1.00 68.14  ? 551 PHE D C   1 
ATOM   18390 O O   . PHE D 1 551 ? 142.732 151.685 160.297 1.00 72.43  ? 551 PHE D O   1 
ATOM   18391 C CB  . PHE D 1 551 ? 141.668 150.809 157.365 1.00 57.80  ? 551 PHE D CB  1 
ATOM   18392 C CG  . PHE D 1 551 ? 140.665 151.474 156.440 1.00 58.10  ? 551 PHE D CG  1 
ATOM   18393 C CD1 . PHE D 1 551 ? 139.557 152.133 156.995 1.00 65.17  ? 551 PHE D CD1 1 
ATOM   18394 C CD2 . PHE D 1 551 ? 140.794 151.407 155.041 1.00 58.78  ? 551 PHE D CD2 1 
ATOM   18395 C CE1 . PHE D 1 551 ? 138.600 152.733 156.165 1.00 66.71  ? 551 PHE D CE1 1 
ATOM   18396 C CE2 . PHE D 1 551 ? 139.828 151.994 154.210 1.00 59.33  ? 551 PHE D CE2 1 
ATOM   18397 C CZ  . PHE D 1 551 ? 138.736 152.666 154.771 1.00 62.94  ? 551 PHE D CZ  1 
ATOM   18398 N N   . ALA D 1 552 ? 144.357 150.494 159.351 1.00 65.89  ? 552 ALA D N   1 
ATOM   18399 C CA  . ALA D 1 552 ? 144.934 150.055 160.621 1.00 58.06  ? 552 ALA D CA  1 
ATOM   18400 C C   . ALA D 1 552 ? 145.501 151.212 161.452 1.00 63.76  ? 552 ALA D C   1 
ATOM   18401 O O   . ALA D 1 552 ? 145.164 151.336 162.627 1.00 67.33  ? 552 ALA D O   1 
ATOM   18402 C CB  . ALA D 1 552 ? 146.008 148.998 160.368 1.00 64.12  ? 552 ALA D CB  1 
ATOM   18403 N N   . VAL D 1 553 ? 146.306 152.109 160.873 1.00 73.55  ? 553 VAL D N   1 
ATOM   18404 C CA  . VAL D 1 553 ? 146.815 153.285 161.607 1.00 67.76  ? 553 VAL D CA  1 
ATOM   18405 C C   . VAL D 1 553 ? 145.682 154.203 162.076 1.00 70.82  ? 553 VAL D C   1 
ATOM   18406 O O   . VAL D 1 553 ? 145.817 154.906 163.073 1.00 72.52  ? 553 VAL D O   1 
ATOM   18407 C CB  . VAL D 1 553 ? 147.840 154.100 160.794 1.00 65.11  ? 553 VAL D CB  1 
ATOM   18408 C CG1 . VAL D 1 553 ? 149.106 153.294 160.529 1.00 66.18  ? 553 VAL D CG1 1 
ATOM   18409 C CG2 . VAL D 1 553 ? 147.330 154.630 159.453 1.00 67.05  ? 553 VAL D CG2 1 
ATOM   18410 N N   . ALA D 1 554 ? 144.544 154.187 161.391 1.00 69.96  ? 554 ALA D N   1 
ATOM   18411 C CA  . ALA D 1 554 ? 143.383 155.004 161.686 1.00 64.91  ? 554 ALA D CA  1 
ATOM   18412 C C   . ALA D 1 554 ? 142.539 154.445 162.828 1.00 72.00  ? 554 ALA D C   1 
ATOM   18413 O O   . ALA D 1 554 ? 142.251 155.158 163.783 1.00 76.31  ? 554 ALA D O   1 
ATOM   18414 C CB  . ALA D 1 554 ? 142.593 155.111 160.394 1.00 63.47  ? 554 ALA D CB  1 
ATOM   18415 N N   . LEU D 1 555 ? 142.187 153.161 162.780 1.00 80.52  ? 555 LEU D N   1 
ATOM   18416 C CA  . LEU D 1 555 ? 141.450 152.504 163.860 1.00 75.29  ? 555 LEU D CA  1 
ATOM   18417 C C   . LEU D 1 555 ? 142.252 152.487 165.158 1.00 74.63  ? 555 LEU D C   1 
ATOM   18418 O O   . LEU D 1 555 ? 141.665 152.710 166.211 1.00 77.83  ? 555 LEU D O   1 
ATOM   18419 C CB  . LEU D 1 555 ? 141.064 151.086 163.431 1.00 73.49  ? 555 LEU D CB  1 
ATOM   18420 C CG  . LEU D 1 555 ? 139.913 151.092 162.418 1.00 77.37  ? 555 LEU D CG  1 
ATOM   18421 C CD1 . LEU D 1 555 ? 139.889 149.781 161.667 1.00 80.50  ? 555 LEU D CD1 1 
ATOM   18422 C CD2 . LEU D 1 555 ? 138.562 151.248 163.104 1.00 76.97  ? 555 LEU D CD2 1 
ATOM   18423 N N   . VAL D 1 556 ? 143.573 152.311 165.104 1.00 73.70  ? 556 VAL D N   1 
ATOM   18424 C CA  . VAL D 1 556 ? 144.452 152.430 166.280 1.00 69.11  ? 556 VAL D CA  1 
ATOM   18425 C C   . VAL D 1 556 ? 144.444 153.839 166.868 1.00 78.11  ? 556 VAL D C   1 
ATOM   18426 O O   . VAL D 1 556 ? 144.333 154.002 168.075 1.00 83.15  ? 556 VAL D O   1 
ATOM   18427 C CB  . VAL D 1 556 ? 145.886 152.017 165.918 1.00 75.27  ? 556 VAL D CB  1 
ATOM   18428 C CG1 . VAL D 1 556 ? 146.905 152.289 167.018 1.00 75.39  ? 556 VAL D CG1 1 
ATOM   18429 C CG2 . VAL D 1 556 ? 145.920 150.523 165.643 1.00 82.31  ? 556 VAL D CG2 1 
ATOM   18430 N N   . SER D 1 557 ? 144.520 154.873 166.029 1.00 85.43  ? 557 SER D N   1 
ATOM   18431 C CA  . SER D 1 557 ? 144.514 156.271 166.471 1.00 80.67  ? 557 SER D CA  1 
ATOM   18432 C C   . SER D 1 557 ? 143.194 156.676 167.122 1.00 79.59  ? 557 SER D C   1 
ATOM   18433 O O   . SER D 1 557 ? 143.195 157.426 168.090 1.00 78.40  ? 557 SER D O   1 
ATOM   18434 C CB  . SER D 1 557 ? 144.795 157.191 165.286 1.00 78.82  ? 557 SER D CB  1 
ATOM   18435 O OG  . SER D 1 557 ? 146.064 156.906 164.741 1.00 78.06  ? 557 SER D OG  1 
ATOM   18436 N N   . LEU D 1 558 ? 142.066 156.172 166.620 1.00 80.65  ? 558 LEU D N   1 
ATOM   18437 C CA  . LEU D 1 558 ? 140.734 156.540 167.090 1.00 77.52  ? 558 LEU D CA  1 
ATOM   18438 C C   . LEU D 1 558 ? 140.224 155.686 168.263 1.00 84.88  ? 558 LEU D C   1 
ATOM   18439 O O   . LEU D 1 558 ? 139.506 156.179 169.127 1.00 86.63  ? 558 LEU D O   1 
ATOM   18440 C CB  . LEU D 1 558 ? 139.799 156.458 165.880 1.00 71.01  ? 558 LEU D CB  1 
ATOM   18441 C CG  . LEU D 1 558 ? 138.502 157.249 166.018 1.00 81.43  ? 558 LEU D CG  1 
ATOM   18442 C CD1 . LEU D 1 558 ? 138.729 158.747 166.202 1.00 78.60  ? 558 LEU D CD1 1 
ATOM   18443 C CD2 . LEU D 1 558 ? 137.704 157.077 164.741 1.00 80.41  ? 558 LEU D CD2 1 
ATOM   18444 N N   . SER D 1 559 ? 140.629 154.415 168.339 1.00 88.53  ? 559 SER D N   1 
ATOM   18445 C CA  . SER D 1 559 ? 140.280 153.512 169.449 1.00 86.88  ? 559 SER D CA  1 
ATOM   18446 C C   . SER D 1 559 ? 141.082 153.767 170.732 1.00 93.63  ? 559 SER D C   1 
ATOM   18447 O O   . SER D 1 559 ? 140.923 153.049 171.719 1.00 95.76  ? 559 SER D O   1 
ATOM   18448 C CB  . SER D 1 559 ? 140.447 152.048 169.046 1.00 90.61  ? 559 SER D CB  1 
ATOM   18449 O OG  . SER D 1 559 ? 139.754 151.791 167.846 1.00 94.97  ? 559 SER D OG  1 
ATOM   18450 N N   . ARG D 1 560 ? 141.962 154.772 170.740 1.00 99.54  ? 560 ARG D N   1 
ATOM   18451 C CA  . ARG D 1 560 ? 142.791 155.154 171.889 1.00 99.51  ? 560 ARG D CA  1 
ATOM   18452 C C   . ARG D 1 560 ? 142.005 155.845 173.013 1.00 99.95  ? 560 ARG D C   1 
ATOM   18453 O O   . ARG D 1 560 ? 142.425 155.793 174.166 1.00 97.44  ? 560 ARG D O   1 
ATOM   18454 C CB  . ARG D 1 560 ? 143.928 156.031 171.346 1.00 101.03 ? 560 ARG D CB  1 
ATOM   18455 C CG  . ARG D 1 560 ? 145.126 156.121 172.297 1.00 100.93 ? 560 ARG D CG  1 
ATOM   18456 C CD  . ARG D 1 560 ? 146.234 157.017 171.727 1.00 101.54 ? 560 ARG D CD  1 
ATOM   18457 N NE  . ARG D 1 560 ? 146.801 156.497 170.468 1.00 101.57 ? 560 ARG D NE  1 
ATOM   18458 C CZ  . ARG D 1 560 ? 147.748 155.590 170.344 1.00 99.82  ? 560 ARG D CZ  1 
ATOM   18459 N NH1 . ARG D 1 560 ? 148.190 155.246 169.172 1.00 96.21  ? 560 ARG D NH1 1 
ATOM   18460 N NH2 . ARG D 1 560 ? 148.290 155.015 171.370 1.00 100.21 ? 560 ARG D NH2 1 
ATOM   18461 N N   . GLU D 1 561 ? 140.855 156.454 172.716 1.00 112.16 ? 561 GLU D N   1 
ATOM   18462 C CA  . GLU D 1 561 ? 140.068 157.237 173.682 1.00 115.04 ? 561 GLU D CA  1 
ATOM   18463 C C   . GLU D 1 561 ? 138.848 156.459 174.216 1.00 112.99 ? 561 GLU D C   1 
ATOM   18464 O O   . GLU D 1 561 ? 137.986 156.021 173.454 1.00 109.01 ? 561 GLU D O   1 
ATOM   18465 C CB  . GLU D 1 561 ? 139.612 158.568 173.047 1.00 114.67 ? 561 GLU D CB  1 
ATOM   18466 C CG  . GLU D 1 561 ? 140.746 159.453 172.508 1.00 111.78 ? 561 GLU D CG  1 
ATOM   18467 C CD  . GLU D 1 561 ? 141.898 159.656 173.507 1.00 115.59 ? 561 GLU D CD  1 
ATOM   18468 O OE1 . GLU D 1 561 ? 141.641 160.098 174.651 1.00 112.12 ? 561 GLU D OE1 1 
ATOM   18469 O OE2 . GLU D 1 561 ? 143.058 159.369 173.140 1.00 116.81 ? 561 GLU D OE2 1 
ATOM   18470 N N   . ALA D 1 562 ? 138.743 156.330 175.541 1.00 114.38 ? 562 ALA D N   1 
ATOM   18471 C CA  . ALA D 1 562 ? 137.594 155.745 176.239 1.00 115.32 ? 562 ALA D CA  1 
ATOM   18472 C C   . ALA D 1 562 ? 136.483 156.778 176.520 1.00 117.00 ? 562 ALA D C   1 
ATOM   18473 O O   . ALA D 1 562 ? 136.741 157.981 176.628 1.00 117.39 ? 562 ALA D O   1 
ATOM   18474 C CB  . ALA D 1 562 ? 138.095 155.082 177.521 1.00 110.72 ? 562 ALA D CB  1 
ATOM   18475 N N   . ARG D 1 563 ? 135.233 156.325 176.631 1.00 111.73 ? 563 ARG D N   1 
ATOM   18476 C CA  . ARG D 1 563 ? 134.051 157.180 176.764 1.00 111.25 ? 563 ARG D CA  1 
ATOM   18477 C C   . ARG D 1 563 ? 133.975 157.905 178.113 1.00 109.78 ? 563 ARG D C   1 
ATOM   18478 O O   . ARG D 1 563 ? 133.511 157.364 179.118 1.00 111.67 ? 563 ARG D O   1 
ATOM   18479 C CB  . ARG D 1 563 ? 132.800 156.343 176.505 1.00 107.83 ? 563 ARG D CB  1 
ATOM   18480 N N   . PRO D 1 589 ? 140.381 144.777 170.934 1.00 113.02 ? 589 PRO D N   1 
ATOM   18481 C CA  . PRO D 1 589 ? 140.809 145.111 169.585 1.00 112.47 ? 589 PRO D CA  1 
ATOM   18482 C C   . PRO D 1 589 ? 141.540 146.456 169.455 1.00 110.98 ? 589 PRO D C   1 
ATOM   18483 O O   . PRO D 1 589 ? 141.454 147.328 170.322 1.00 105.95 ? 589 PRO D O   1 
ATOM   18484 C CB  . PRO D 1 589 ? 139.525 145.074 168.753 1.00 112.55 ? 589 PRO D CB  1 
ATOM   18485 C CG  . PRO D 1 589 ? 138.712 143.988 169.441 1.00 108.68 ? 589 PRO D CG  1 
ATOM   18486 C CD  . PRO D 1 589 ? 139.048 144.213 170.911 1.00 111.28 ? 589 PRO D CD  1 
ATOM   18487 N N   . TYR D 1 590 ? 142.236 146.632 168.327 1.00 105.98 ? 590 TYR D N   1 
ATOM   18488 C CA  . TYR D 1 590 ? 142.833 147.899 167.868 1.00 103.67 ? 590 TYR D CA  1 
ATOM   18489 C C   . TYR D 1 590 ? 143.863 148.534 168.823 1.00 99.99  ? 590 TYR D C   1 
ATOM   18490 O O   . TYR D 1 590 ? 144.036 149.748 168.839 1.00 97.79  ? 590 TYR D O   1 
ATOM   18491 C CB  . TYR D 1 590 ? 141.726 148.920 167.586 1.00 100.81 ? 590 TYR D CB  1 
ATOM   18492 C CG  . TYR D 1 590 ? 140.543 148.360 166.840 1.00 101.34 ? 590 TYR D CG  1 
ATOM   18493 C CD1 . TYR D 1 590 ? 140.657 147.957 165.520 1.00 101.38 ? 590 TYR D CD1 1 
ATOM   18494 C CD2 . TYR D 1 590 ? 139.309 148.225 167.454 1.00 99.35  ? 590 TYR D CD2 1 
ATOM   18495 C CE1 . TYR D 1 590 ? 139.577 147.435 164.828 1.00 102.83 ? 590 TYR D CE1 1 
ATOM   18496 C CE2 . TYR D 1 590 ? 138.219 147.706 166.778 1.00 100.41 ? 590 TYR D CE2 1 
ATOM   18497 C CZ  . TYR D 1 590 ? 138.353 147.310 165.460 1.00 103.77 ? 590 TYR D CZ  1 
ATOM   18498 O OH  . TYR D 1 590 ? 137.283 146.796 164.788 1.00 102.97 ? 590 TYR D OH  1 
ATOM   18499 N N   . ARG D 1 591 ? 144.570 147.724 169.615 1.00 103.48 ? 591 ARG D N   1 
ATOM   18500 C CA  . ARG D 1 591 ? 145.576 148.191 170.572 1.00 104.14 ? 591 ARG D CA  1 
ATOM   18501 C C   . ARG D 1 591 ? 146.910 148.613 169.938 1.00 103.67 ? 591 ARG D C   1 
ATOM   18502 O O   . ARG D 1 591 ? 147.637 149.429 170.504 1.00 103.73 ? 591 ARG D O   1 
ATOM   18503 C CB  . ARG D 1 591 ? 145.829 147.072 171.574 1.00 98.86  ? 591 ARG D CB  1 
ATOM   18504 N N   . SER D 1 592 ? 147.254 148.066 168.770 1.00 91.79  ? 592 SER D N   1 
ATOM   18505 C CA  . SER D 1 592 ? 148.531 148.292 168.080 1.00 92.93  ? 592 SER D CA  1 
ATOM   18506 C C   . SER D 1 592 ? 148.376 148.135 166.569 1.00 91.19  ? 592 SER D C   1 
ATOM   18507 O O   . SER D 1 592 ? 147.376 147.593 166.103 1.00 91.10  ? 592 SER D O   1 
ATOM   18508 C CB  . SER D 1 592 ? 149.616 147.340 168.607 1.00 94.20  ? 592 SER D CB  1 
ATOM   18509 O OG  . SER D 1 592 ? 149.492 146.036 168.071 1.00 98.00  ? 592 SER D OG  1 
ATOM   18510 N N   . ILE D 1 593 ? 149.355 148.584 165.778 1.00 90.67  ? 593 ILE D N   1 
ATOM   18511 C CA  . ILE D 1 593 ? 149.312 148.454 164.312 1.00 90.67  ? 593 ILE D CA  1 
ATOM   18512 C C   . ILE D 1 593 ? 149.222 146.983 163.890 1.00 89.85  ? 593 ILE D C   1 
ATOM   18513 O O   . ILE D 1 593 ? 148.479 146.661 162.965 1.00 92.66  ? 593 ILE D O   1 
ATOM   18514 C CB  . ILE D 1 593 ? 150.531 149.129 163.638 1.00 92.36  ? 593 ILE D CB  1 
ATOM   18515 C CG1 . ILE D 1 593 ? 150.792 150.582 164.086 1.00 91.13  ? 593 ILE D CG1 1 
ATOM   18516 C CG2 . ILE D 1 593 ? 150.391 149.078 162.109 1.00 87.30  ? 593 ILE D CG2 1 
ATOM   18517 C CD1 . ILE D 1 593 ? 149.601 151.525 163.936 1.00 91.58  ? 593 ILE D CD1 1 
ATOM   18518 N N   . LEU D 1 594 ? 149.930 146.082 164.579 1.00 87.34  ? 594 LEU D N   1 
ATOM   18519 C CA  . LEU D 1 594 ? 149.874 144.641 164.335 1.00 90.86  ? 594 LEU D CA  1 
ATOM   18520 C C   . LEU D 1 594 ? 148.483 144.082 164.647 1.00 92.67  ? 594 LEU D C   1 
ATOM   18521 O O   . LEU D 1 594 ? 147.889 143.427 163.799 1.00 96.34  ? 594 LEU D O   1 
ATOM   18522 C CB  . LEU D 1 594 ? 150.975 143.949 165.160 1.00 95.30  ? 594 LEU D CB  1 
ATOM   18523 C CG  . LEU D 1 594 ? 150.939 142.409 165.127 1.00 96.66  ? 594 LEU D CG  1 
ATOM   18524 C CD1 . LEU D 1 594 ? 151.101 141.846 163.720 1.00 91.56  ? 594 LEU D CD1 1 
ATOM   18525 C CD2 . LEU D 1 594 ? 152.058 141.858 166.004 1.00 91.87  ? 594 LEU D CD2 1 
ATOM   18526 N N   . ASP D 1 595 ? 147.939 144.373 165.828 1.00 87.55  ? 595 ASP D N   1 
ATOM   18527 C CA  . ASP D 1 595 ? 146.622 143.876 166.229 1.00 85.20  ? 595 ASP D CA  1 
ATOM   18528 C C   . ASP D 1 595 ? 145.501 144.399 165.329 1.00 89.27  ? 595 ASP D C   1 
ATOM   18529 O O   . ASP D 1 595 ? 144.649 143.625 164.915 1.00 92.26  ? 595 ASP D O   1 
ATOM   18530 C CB  . ASP D 1 595 ? 146.337 144.242 167.689 1.00 94.94  ? 595 ASP D CB  1 
ATOM   18531 C CG  . ASP D 1 595 ? 147.371 143.663 168.652 1.00 101.45 ? 595 ASP D CG  1 
ATOM   18532 O OD1 . ASP D 1 595 ? 147.608 142.437 168.621 1.00 96.51  ? 595 ASP D OD1 1 
ATOM   18533 O OD2 . ASP D 1 595 ? 147.959 144.453 169.427 1.00 102.93 ? 595 ASP D OD2 1 
ATOM   18534 N N   . ALA D 1 596 ? 145.506 145.682 164.963 1.00 87.25  ? 596 ALA D N   1 
ATOM   18535 C CA  . ALA D 1 596 ? 144.540 146.237 164.021 1.00 80.05  ? 596 ALA D CA  1 
ATOM   18536 C C   . ALA D 1 596 ? 144.714 145.678 162.605 1.00 79.86  ? 596 ALA D C   1 
ATOM   18537 O O   . ALA D 1 596 ? 143.725 145.351 161.969 1.00 85.49  ? 596 ALA D O   1 
ATOM   18538 C CB  . ALA D 1 596 ? 144.650 147.754 164.036 1.00 78.13  ? 596 ALA D CB  1 
ATOM   18539 N N   . SER D 1 597 ? 145.942 145.481 162.122 1.00 80.04  ? 597 SER D N   1 
ATOM   18540 C CA  . SER D 1 597 ? 146.179 144.798 160.845 1.00 72.13  ? 597 SER D CA  1 
ATOM   18541 C C   . SER D 1 597 ? 145.653 143.370 160.869 1.00 73.22  ? 597 SER D C   1 
ATOM   18542 O O   . SER D 1 597 ? 145.114 142.908 159.875 1.00 81.98  ? 597 SER D O   1 
ATOM   18543 C CB  . SER D 1 597 ? 147.668 144.753 160.491 1.00 78.38  ? 597 SER D CB  1 
ATOM   18544 O OG  . SER D 1 597 ? 148.208 146.052 160.376 1.00 86.22  ? 597 SER D OG  1 
ATOM   18545 N N   . LEU D 1 598 ? 145.761 142.662 161.995 1.00 77.79  ? 598 LEU D N   1 
ATOM   18546 C CA  . LEU D 1 598 ? 145.268 141.299 162.128 1.00 80.55  ? 598 LEU D CA  1 
ATOM   18547 C C   . LEU D 1 598 ? 143.740 141.230 162.255 1.00 81.77  ? 598 LEU D C   1 
ATOM   18548 O O   . LEU D 1 598 ? 143.115 140.410 161.596 1.00 90.73  ? 598 LEU D O   1 
ATOM   18549 C CB  . LEU D 1 598 ? 146.003 140.636 163.300 1.00 76.49  ? 598 LEU D CB  1 
ATOM   18550 C CG  . LEU D 1 598 ? 145.845 139.114 163.332 1.00 83.69  ? 598 LEU D CG  1 
ATOM   18551 C CD1 . LEU D 1 598 ? 146.511 138.451 162.128 1.00 82.50  ? 598 LEU D CD1 1 
ATOM   18552 C CD2 . LEU D 1 598 ? 146.483 138.566 164.600 1.00 80.72  ? 598 LEU D CD2 1 
ATOM   18553 N N   . GLU D 1 599 ? 143.106 142.108 163.026 1.00 74.09  ? 599 GLU D N   1 
ATOM   18554 C CA  . GLU D 1 599 ? 141.644 142.214 163.106 1.00 68.33  ? 599 GLU D CA  1 
ATOM   18555 C C   . GLU D 1 599 ? 141.018 142.618 161.770 1.00 71.42  ? 599 GLU D C   1 
ATOM   18556 O O   . GLU D 1 599 ? 140.028 142.028 161.347 1.00 75.44  ? 599 GLU D O   1 
ATOM   18557 C CB  . GLU D 1 599 ? 141.247 143.229 164.189 1.00 78.34  ? 599 GLU D CB  1 
ATOM   18558 C CG  . GLU D 1 599 ? 141.503 142.763 165.631 1.00 82.84  ? 599 GLU D CG  1 
ATOM   18559 C CD  . GLU D 1 599 ? 140.838 141.423 165.980 1.00 84.59  ? 599 GLU D CD  1 
ATOM   18560 O OE1 . GLU D 1 599 ? 139.710 141.172 165.524 1.00 82.39  ? 599 GLU D OE1 1 
ATOM   18561 O OE2 . GLU D 1 599 ? 141.463 140.595 166.682 1.00 82.64  ? 599 GLU D OE2 1 
ATOM   18562 N N   . LEU D 1 600 ? 141.612 143.578 161.058 1.00 63.30  ? 600 LEU D N   1 
ATOM   18563 C CA  . LEU D 1 600 ? 141.214 143.928 159.699 1.00 51.34  ? 600 LEU D CA  1 
ATOM   18564 C C   . LEU D 1 600 ? 141.531 142.825 158.694 1.00 42.46  ? 600 LEU D C   1 
ATOM   18565 O O   . LEU D 1 600 ? 140.798 142.668 157.723 1.00 51.92  ? 600 LEU D O   1 
ATOM   18566 C CB  . LEU D 1 600 ? 141.921 145.209 159.260 1.00 64.09  ? 600 LEU D CB  1 
ATOM   18567 C CG  . LEU D 1 600 ? 141.470 146.514 159.918 1.00 53.68  ? 600 LEU D CG  1 
ATOM   18568 C CD1 . LEU D 1 600 ? 142.257 147.636 159.255 1.00 58.16  ? 600 LEU D CD1 1 
ATOM   18569 C CD2 . LEU D 1 600 ? 139.988 146.766 159.703 1.00 57.26  ? 600 LEU D CD2 1 
ATOM   18570 N N   . PHE D 1 601 ? 142.592 142.039 158.877 1.00 57.21  ? 601 PHE D N   1 
ATOM   18571 C CA  . PHE D 1 601 ? 142.839 140.915 157.980 1.00 62.58  ? 601 PHE D CA  1 
ATOM   18572 C C   . PHE D 1 601 ? 141.812 139.800 158.198 1.00 71.73  ? 601 PHE D C   1 
ATOM   18573 O O   . PHE D 1 601 ? 141.315 139.231 157.229 1.00 67.31  ? 601 PHE D O   1 
ATOM   18574 C CB  . PHE D 1 601 ? 144.265 140.384 158.133 1.00 60.29  ? 601 PHE D CB  1 
ATOM   18575 C CG  . PHE D 1 601 ? 144.522 139.186 157.247 1.00 67.25  ? 601 PHE D CG  1 
ATOM   18576 C CD1 . PHE D 1 601 ? 144.708 139.362 155.865 1.00 67.56  ? 601 PHE D CD1 1 
ATOM   18577 C CD2 . PHE D 1 601 ? 144.482 137.883 157.780 1.00 73.35  ? 601 PHE D CD2 1 
ATOM   18578 C CE1 . PHE D 1 601 ? 144.845 138.246 155.024 1.00 68.06  ? 601 PHE D CE1 1 
ATOM   18579 C CE2 . PHE D 1 601 ? 144.618 136.770 156.940 1.00 66.49  ? 601 PHE D CE2 1 
ATOM   18580 C CZ  . PHE D 1 601 ? 144.792 136.950 155.558 1.00 67.07  ? 601 PHE D CZ  1 
ATOM   18581 N N   . LYS D 1 602 ? 141.381 139.547 159.436 1.00 78.66  ? 602 LYS D N   1 
ATOM   18582 C CA  . LYS D 1 602 ? 140.377 138.529 159.726 1.00 54.48  ? 602 LYS D CA  1 
ATOM   18583 C C   . LYS D 1 602 ? 139.072 138.696 158.954 1.00 51.26  ? 602 LYS D C   1 
ATOM   18584 O O   . LYS D 1 602 ? 138.439 137.695 158.646 1.00 70.64  ? 602 LYS D O   1 
ATOM   18585 C CB  . LYS D 1 602 ? 140.123 138.435 161.228 1.00 61.47  ? 602 LYS D CB  1 
ATOM   18586 C CG  . LYS D 1 602 ? 141.134 137.508 161.901 1.00 62.44  ? 602 LYS D CG  1 
ATOM   18587 C CD  . LYS D 1 602 ? 140.741 137.198 163.348 1.00 62.42  ? 602 LYS D CD  1 
ATOM   18588 C CE  . LYS D 1 602 ? 141.074 138.376 164.257 1.00 70.18  ? 602 LYS D CE  1 
ATOM   18589 N NZ  . LYS D 1 602 ? 140.693 138.125 165.663 1.00 75.82  ? 602 LYS D NZ  1 
ATOM   18590 N N   . PHE D 1 603 ? 138.688 139.894 158.516 1.00 66.12  ? 603 PHE D N   1 
ATOM   18591 C CA  . PHE D 1 603 ? 137.523 140.103 157.637 1.00 71.80  ? 603 PHE D CA  1 
ATOM   18592 C C   . PHE D 1 603 ? 137.601 139.389 156.282 1.00 71.13  ? 603 PHE D C   1 
ATOM   18593 O O   . PHE D 1 603 ? 136.564 139.121 155.684 1.00 73.97  ? 603 PHE D O   1 
ATOM   18594 C CB  . PHE D 1 603 ? 137.342 141.591 157.350 1.00 65.53  ? 603 PHE D CB  1 
ATOM   18595 C CG  . PHE D 1 603 ? 136.636 142.354 158.440 1.00 67.28  ? 603 PHE D CG  1 
ATOM   18596 C CD1 . PHE D 1 603 ? 135.237 142.413 158.444 1.00 65.03  ? 603 PHE D CD1 1 
ATOM   18597 C CD2 . PHE D 1 603 ? 137.369 143.003 159.441 1.00 67.75  ? 603 PHE D CD2 1 
ATOM   18598 C CE1 . PHE D 1 603 ? 134.571 143.156 159.428 1.00 63.33  ? 603 PHE D CE1 1 
ATOM   18599 C CE2 . PHE D 1 603 ? 136.701 143.745 160.430 1.00 66.60  ? 603 PHE D CE2 1 
ATOM   18600 C CZ  . PHE D 1 603 ? 135.307 143.825 160.420 1.00 66.74  ? 603 PHE D CZ  1 
ATOM   18601 N N   . THR D 1 604 ? 138.795 139.095 155.775 1.00 70.57  ? 604 THR D N   1 
ATOM   18602 C CA  . THR D 1 604 ? 138.959 138.391 154.495 1.00 63.22  ? 604 THR D CA  1 
ATOM   18603 C C   . THR D 1 604 ? 138.879 136.874 154.646 1.00 75.92  ? 604 THR D C   1 
ATOM   18604 O O   . THR D 1 604 ? 138.490 136.201 153.696 1.00 78.60  ? 604 THR D O   1 
ATOM   18605 C CB  . THR D 1 604 ? 140.260 138.769 153.794 1.00 63.29  ? 604 THR D CB  1 
ATOM   18606 O OG1 . THR D 1 604 ? 141.378 138.363 154.539 1.00 67.46  ? 604 THR D OG1 1 
ATOM   18607 C CG2 . THR D 1 604 ? 140.358 140.264 153.547 1.00 75.10  ? 604 THR D CG2 1 
ATOM   18608 N N   . ILE D 1 605 ? 139.167 136.323 155.837 1.00 74.54  ? 605 ILE D N   1 
ATOM   18609 C CA  . ILE D 1 605 ? 138.947 134.895 156.134 1.00 64.19  ? 605 ILE D CA  1 
ATOM   18610 C C   . ILE D 1 605 ? 137.532 134.589 156.674 1.00 63.45  ? 605 ILE D C   1 
ATOM   18611 O O   . ILE D 1 605 ? 137.255 133.457 157.050 1.00 66.40  ? 605 ILE D O   1 
ATOM   18612 C CB  . ILE D 1 605 ? 140.056 134.334 157.043 1.00 58.94  ? 605 ILE D CB  1 
ATOM   18613 C CG1 . ILE D 1 605 ? 139.985 134.857 158.485 1.00 61.60  ? 605 ILE D CG1 1 
ATOM   18614 C CG2 . ILE D 1 605 ? 141.433 134.601 156.429 1.00 59.44  ? 605 ILE D CG2 1 
ATOM   18615 C CD1 . ILE D 1 605 ? 140.801 134.049 159.486 1.00 56.83  ? 605 ILE D CD1 1 
ATOM   18616 N N   . GLY D 1 606 ? 136.645 135.586 156.730 1.00 59.82  ? 606 GLY D N   1 
ATOM   18617 C CA  . GLY D 1 606 ? 135.276 135.463 157.226 1.00 56.98  ? 606 GLY D CA  1 
ATOM   18618 C C   . GLY D 1 606 ? 135.101 135.554 158.746 1.00 69.22  ? 606 GLY D C   1 
ATOM   18619 O O   . GLY D 1 606 ? 134.025 135.219 159.228 1.00 75.55  ? 606 GLY D O   1 
ATOM   18620 N N   . MET D 1 607 ? 136.112 136.005 159.507 1.00 67.07  ? 607 MET D N   1 
ATOM   18621 C CA  . MET D 1 607 ? 136.113 136.068 160.983 1.00 64.06  ? 607 MET D CA  1 
ATOM   18622 C C   . MET D 1 607 ? 136.081 137.506 161.521 1.00 62.34  ? 607 MET D C   1 
ATOM   18623 O O   . MET D 1 607 ? 136.806 137.853 162.443 1.00 67.09  ? 607 MET D O   1 
ATOM   18624 C CB  . MET D 1 607 ? 137.278 135.241 161.556 1.00 64.06  ? 607 MET D CB  1 
ATOM   18625 C CG  . MET D 1 607 ? 137.081 133.733 161.378 1.00 61.75  ? 607 MET D CG  1 
ATOM   18626 S SD  . MET D 1 607 ? 135.884 132.958 162.496 1.00 63.01  ? 607 MET D SD  1 
ATOM   18627 C CE  . MET D 1 607 ? 136.807 132.865 164.043 1.00 60.99  ? 607 MET D CE  1 
ATOM   18628 N N   . GLY D 1 608 ? 135.296 138.387 160.898 1.00 67.37  ? 608 GLY D N   1 
ATOM   18629 C CA  . GLY D 1 608 ? 135.409 139.843 161.028 1.00 67.92  ? 608 GLY D CA  1 
ATOM   18630 C C   . GLY D 1 608 ? 135.266 140.477 162.422 1.00 74.14  ? 608 GLY D C   1 
ATOM   18631 O O   . GLY D 1 608 ? 135.933 141.464 162.694 1.00 85.52  ? 608 GLY D O   1 
ATOM   18632 N N   . GLU D 1 609 ? 134.418 139.961 163.314 1.00 87.10  ? 609 GLU D N   1 
ATOM   18633 C CA  . GLU D 1 609 ? 134.182 140.562 164.650 1.00 91.22  ? 609 GLU D CA  1 
ATOM   18634 C C   . GLU D 1 609 ? 133.717 142.041 164.584 1.00 89.62  ? 609 GLU D C   1 
ATOM   18635 O O   . GLU D 1 609 ? 134.141 142.900 165.355 1.00 88.49  ? 609 GLU D O   1 
ATOM   18636 C CB  . GLU D 1 609 ? 135.368 140.321 165.620 1.00 91.12  ? 609 GLU D CB  1 
ATOM   18637 C CG  . GLU D 1 609 ? 135.697 138.831 165.820 1.00 95.08  ? 609 GLU D CG  1 
ATOM   18638 C CD  . GLU D 1 609 ? 136.915 138.610 166.733 1.00 97.36  ? 609 GLU D CD  1 
ATOM   18639 O OE1 . GLU D 1 609 ? 136.834 138.964 167.931 1.00 93.83  ? 609 GLU D OE1 1 
ATOM   18640 O OE2 . GLU D 1 609 ? 137.928 138.021 166.281 1.00 98.11  ? 609 GLU D OE2 1 
ATOM   18641 N N   . LEU D 1 610 ? 132.822 142.342 163.639 1.00 81.33  ? 610 LEU D N   1 
ATOM   18642 C CA  . LEU D 1 610 ? 132.219 143.656 163.390 1.00 77.94  ? 610 LEU D CA  1 
ATOM   18643 C C   . LEU D 1 610 ? 131.181 144.040 164.464 1.00 80.86  ? 610 LEU D C   1 
ATOM   18644 O O   . LEU D 1 610 ? 130.139 143.399 164.566 1.00 84.45  ? 610 LEU D O   1 
ATOM   18645 C CB  . LEU D 1 610 ? 131.585 143.561 161.991 1.00 80.88  ? 610 LEU D CB  1 
ATOM   18646 C CG  . LEU D 1 610 ? 130.873 144.807 161.469 1.00 81.44  ? 610 LEU D CG  1 
ATOM   18647 C CD1 . LEU D 1 610 ? 131.807 145.992 161.282 1.00 83.52  ? 610 LEU D CD1 1 
ATOM   18648 C CD2 . LEU D 1 610 ? 130.285 144.490 160.105 1.00 81.25  ? 610 LEU D CD2 1 
ATOM   18649 N N   . ALA D 1 611 ? 131.429 145.081 165.260 1.00 99.90  ? 611 ALA D N   1 
ATOM   18650 C CA  . ALA D 1 611 ? 130.585 145.430 166.408 1.00 99.36  ? 611 ALA D CA  1 
ATOM   18651 C C   . ALA D 1 611 ? 130.609 146.925 166.768 1.00 101.47 ? 611 ALA D C   1 
ATOM   18652 O O   . ALA D 1 611 ? 131.587 147.627 166.517 1.00 103.85 ? 611 ALA D O   1 
ATOM   18653 C CB  . ALA D 1 611 ? 131.036 144.594 167.612 1.00 96.19  ? 611 ALA D CB  1 
ATOM   18654 N N   . PHE D 1 612 ? 129.547 147.398 167.422 1.00 106.52 ? 612 PHE D N   1 
ATOM   18655 C CA  . PHE D 1 612 ? 129.453 148.732 168.017 1.00 105.40 ? 612 PHE D CA  1 
ATOM   18656 C C   . PHE D 1 612 ? 130.088 148.726 169.420 1.00 106.94 ? 612 PHE D C   1 
ATOM   18657 O O   . PHE D 1 612 ? 129.418 148.445 170.412 1.00 108.04 ? 612 PHE D O   1 
ATOM   18658 C CB  . PHE D 1 612 ? 127.969 149.133 168.018 1.00 105.42 ? 612 PHE D CB  1 
ATOM   18659 C CG  . PHE D 1 612 ? 127.663 150.551 168.447 1.00 108.01 ? 612 PHE D CG  1 
ATOM   18660 C CD1 . PHE D 1 612 ? 127.879 151.617 167.559 1.00 106.04 ? 612 PHE D CD1 1 
ATOM   18661 C CD2 . PHE D 1 612 ? 127.083 150.804 169.704 1.00 106.98 ? 612 PHE D CD2 1 
ATOM   18662 C CE1 . PHE D 1 612 ? 127.504 152.921 167.911 1.00 106.21 ? 612 PHE D CE1 1 
ATOM   18663 C CE2 . PHE D 1 612 ? 126.698 152.109 170.054 1.00 105.99 ? 612 PHE D CE2 1 
ATOM   18664 C CZ  . PHE D 1 612 ? 126.907 153.169 169.159 1.00 106.30 ? 612 PHE D CZ  1 
ATOM   18665 N N   . GLN D 1 613 ? 131.400 148.971 169.500 1.00 111.68 ? 613 GLN D N   1 
ATOM   18666 C CA  . GLN D 1 613 ? 132.200 148.835 170.727 1.00 113.07 ? 613 GLN D CA  1 
ATOM   18667 C C   . GLN D 1 613 ? 131.707 149.775 171.841 1.00 112.93 ? 613 GLN D C   1 
ATOM   18668 O O   . GLN D 1 613 ? 131.753 150.991 171.686 1.00 112.90 ? 613 GLN D O   1 
ATOM   18669 C CB  . GLN D 1 613 ? 133.675 149.153 170.409 1.00 109.90 ? 613 GLN D CB  1 
ATOM   18670 C CG  . GLN D 1 613 ? 134.347 148.249 169.362 1.00 111.97 ? 613 GLN D CG  1 
ATOM   18671 C CD  . GLN D 1 613 ? 134.592 146.814 169.820 1.00 115.79 ? 613 GLN D CD  1 
ATOM   18672 O OE1 . GLN D 1 613 ? 134.408 146.440 170.968 1.00 115.54 ? 613 GLN D OE1 1 
ATOM   18673 N NE2 . GLN D 1 613 ? 135.025 145.946 168.937 1.00 110.67 ? 613 GLN D NE2 1 
ATOM   18674 N N   . GLU D 1 614 ? 131.235 149.270 172.981 1.00 118.01 ? 614 GLU D N   1 
ATOM   18675 C CA  . GLU D 1 614 ? 130.539 150.119 173.961 1.00 118.38 ? 614 GLU D CA  1 
ATOM   18676 C C   . GLU D 1 614 ? 131.450 151.131 174.687 1.00 121.37 ? 614 GLU D C   1 
ATOM   18677 O O   . GLU D 1 614 ? 130.996 152.226 175.017 1.00 120.85 ? 614 GLU D O   1 
ATOM   18678 C CB  . GLU D 1 614 ? 129.807 149.261 175.005 1.00 117.04 ? 614 GLU D CB  1 
ATOM   18679 N N   . GLN D 1 615 ? 132.713 150.785 174.951 1.00 118.27 ? 615 GLN D N   1 
ATOM   18680 C CA  . GLN D 1 615 ? 133.616 151.554 175.815 1.00 115.14 ? 615 GLN D CA  1 
ATOM   18681 C C   . GLN D 1 615 ? 134.385 152.683 175.110 1.00 116.41 ? 615 GLN D C   1 
ATOM   18682 O O   . GLN D 1 615 ? 134.907 153.573 175.781 1.00 118.78 ? 615 GLN D O   1 
ATOM   18683 C CB  . GLN D 1 615 ? 134.571 150.595 176.557 1.00 112.47 ? 615 GLN D CB  1 
ATOM   18684 C CG  . GLN D 1 615 ? 135.865 150.161 175.838 1.00 113.92 ? 615 GLN D CG  1 
ATOM   18685 C CD  . GLN D 1 615 ? 135.690 149.180 174.680 1.00 117.31 ? 615 GLN D CD  1 
ATOM   18686 O OE1 . GLN D 1 615 ? 134.596 148.859 174.243 1.00 117.97 ? 615 GLN D OE1 1 
ATOM   18687 N NE2 . GLN D 1 615 ? 136.767 148.663 174.137 1.00 115.18 ? 615 GLN D NE2 1 
ATOM   18688 N N   . LEU D 1 616 ? 134.496 152.649 173.777 1.00 106.51 ? 616 LEU D N   1 
ATOM   18689 C CA  . LEU D 1 616 ? 135.237 153.647 172.998 1.00 106.35 ? 616 LEU D CA  1 
ATOM   18690 C C   . LEU D 1 616 ? 134.464 154.971 172.913 1.00 106.12 ? 616 LEU D C   1 
ATOM   18691 O O   . LEU D 1 616 ? 133.248 154.968 172.736 1.00 107.10 ? 616 LEU D O   1 
ATOM   18692 C CB  . LEU D 1 616 ? 135.552 153.107 171.586 1.00 104.60 ? 616 LEU D CB  1 
ATOM   18693 C CG  . LEU D 1 616 ? 136.389 151.818 171.534 1.00 104.31 ? 616 LEU D CG  1 
ATOM   18694 C CD1 . LEU D 1 616 ? 136.676 151.453 170.081 1.00 101.63 ? 616 LEU D CD1 1 
ATOM   18695 C CD2 . LEU D 1 616 ? 137.726 151.967 172.254 1.00 104.26 ? 616 LEU D CD2 1 
ATOM   18696 N N   . ARG D 1 617 ? 135.149 156.121 172.972 1.00 95.70  ? 617 ARG D N   1 
ATOM   18697 C CA  . ARG D 1 617 ? 134.467 157.451 172.915 1.00 95.42  ? 617 ARG D CA  1 
ATOM   18698 C C   . ARG D 1 617 ? 133.880 157.679 171.530 1.00 97.10  ? 617 ARG D C   1 
ATOM   18699 O O   . ARG D 1 617 ? 132.746 158.162 171.456 1.00 91.06  ? 617 ARG D O   1 
ATOM   18700 C CB  . ARG D 1 617 ? 135.467 158.565 173.223 1.00 90.97  ? 617 ARG D CB  1 
ATOM   18701 C CG  . ARG D 1 617 ? 134.862 159.946 173.420 1.00 90.08  ? 617 ARG D CG  1 
ATOM   18702 C CD  . ARG D 1 617 ? 136.002 160.941 173.508 1.00 95.52  ? 617 ARG D CD  1 
ATOM   18703 N NE  . ARG D 1 617 ? 135.726 162.178 174.224 1.00 98.54  ? 617 ARG D NE  1 
ATOM   18704 C CZ  . ARG D 1 617 ? 135.268 163.293 173.668 1.00 98.75  ? 617 ARG D CZ  1 
ATOM   18705 N NH1 . ARG D 1 617 ? 135.061 164.365 174.412 1.00 96.79  ? 617 ARG D NH1 1 
ATOM   18706 N NH2 . ARG D 1 617 ? 135.009 163.335 172.375 1.00 98.63  ? 617 ARG D NH2 1 
ATOM   18707 N N   . PHE D 1 618 ? 134.630 157.350 170.482 1.00 96.62  ? 618 PHE D N   1 
ATOM   18708 C CA  . PHE D 1 618 ? 134.258 157.513 169.074 1.00 90.72  ? 618 PHE D CA  1 
ATOM   18709 C C   . PHE D 1 618 ? 133.698 156.220 168.456 1.00 92.95  ? 618 PHE D C   1 
ATOM   18710 O O   . PHE D 1 618 ? 133.926 155.942 167.282 1.00 95.13  ? 618 PHE D O   1 
ATOM   18711 C CB  . PHE D 1 618 ? 135.464 158.068 168.303 1.00 89.94  ? 618 PHE D CB  1 
ATOM   18712 C CG  . PHE D 1 618 ? 135.999 159.379 168.841 1.00 89.91  ? 618 PHE D CG  1 
ATOM   18713 C CD1 . PHE D 1 618 ? 135.256 160.561 168.686 1.00 86.79  ? 618 PHE D CD1 1 
ATOM   18714 C CD2 . PHE D 1 618 ? 137.229 159.415 169.515 1.00 89.34  ? 618 PHE D CD2 1 
ATOM   18715 C CE1 . PHE D 1 618 ? 135.731 161.768 169.222 1.00 84.37  ? 618 PHE D CE1 1 
ATOM   18716 C CE2 . PHE D 1 618 ? 137.701 160.620 170.054 1.00 90.64  ? 618 PHE D CE2 1 
ATOM   18717 C CZ  . PHE D 1 618 ? 136.956 161.797 169.907 1.00 88.47  ? 618 PHE D CZ  1 
ATOM   18718 N N   . ARG D 1 619 ? 133.012 155.380 169.233 1.00 102.49 ? 619 ARG D N   1 
ATOM   18719 C CA  . ARG D 1 619 ? 132.546 154.033 168.774 1.00 97.93  ? 619 ARG D CA  1 
ATOM   18720 C C   . ARG D 1 619 ? 131.702 154.037 167.494 1.00 96.19  ? 619 ARG D C   1 
ATOM   18721 O O   . ARG D 1 619 ? 131.743 153.027 166.797 1.00 97.02  ? 619 ARG D O   1 
ATOM   18722 C CB  . ARG D 1 619 ? 131.763 153.369 169.907 1.00 102.06 ? 619 ARG D CB  1 
ATOM   18723 C CG  . ARG D 1 619 ? 130.467 154.074 170.275 1.00 100.28 ? 619 ARG D CG  1 
ATOM   18724 C CD  . ARG D 1 619 ? 129.925 153.557 171.589 1.00 100.09 ? 619 ARG D CD  1 
ATOM   18725 N NE  . ARG D 1 619 ? 128.792 154.350 172.037 1.00 103.79 ? 619 ARG D NE  1 
ATOM   18726 C CZ  . ARG D 1 619 ? 128.198 154.207 173.214 1.00 102.50 ? 619 ARG D CZ  1 
ATOM   18727 N NH1 . ARG D 1 619 ? 127.169 154.974 173.531 1.00 98.34  ? 619 ARG D NH1 1 
ATOM   18728 N NH2 . ARG D 1 619 ? 128.636 153.303 174.070 1.00 100.97 ? 619 ARG D NH2 1 
ATOM   18729 N N   . GLY D 1 620 ? 130.888 155.049 167.241 1.00 83.47  ? 620 GLY D N   1 
ATOM   18730 C CA  . GLY D 1 620 ? 130.165 155.159 165.973 1.00 87.03  ? 620 GLY D CA  1 
ATOM   18731 C C   . GLY D 1 620 ? 131.082 155.433 164.781 1.00 87.54  ? 620 GLY D C   1 
ATOM   18732 O O   . GLY D 1 620 ? 130.877 154.887 163.703 1.00 84.70  ? 620 GLY D O   1 
ATOM   18733 N N   . VAL D 1 621 ? 132.140 156.222 164.968 1.00 88.88  ? 621 VAL D N   1 
ATOM   18734 C CA  . VAL D 1 621 ? 133.122 156.514 163.914 1.00 86.75  ? 621 VAL D CA  1 
ATOM   18735 C C   . VAL D 1 621 ? 134.041 155.316 163.679 1.00 83.70  ? 621 VAL D C   1 
ATOM   18736 O O   . VAL D 1 621 ? 134.340 154.998 162.537 1.00 86.47  ? 621 VAL D O   1 
ATOM   18737 C CB  . VAL D 1 621 ? 133.936 157.783 164.216 1.00 85.17  ? 621 VAL D CB  1 
ATOM   18738 C CG1 . VAL D 1 621 ? 134.759 158.181 162.989 1.00 84.69  ? 621 VAL D CG1 1 
ATOM   18739 C CG2 . VAL D 1 621 ? 133.053 158.981 164.575 1.00 87.41  ? 621 VAL D CG2 1 
ATOM   18740 N N   . VAL D 1 622 ? 134.429 154.593 164.731 1.00 79.29  ? 622 VAL D N   1 
ATOM   18741 C CA  . VAL D 1 622 ? 135.150 153.314 164.620 1.00 77.91  ? 622 VAL D CA  1 
ATOM   18742 C C   . VAL D 1 622 ? 134.320 152.282 163.847 1.00 81.86  ? 622 VAL D C   1 
ATOM   18743 O O   . VAL D 1 622 ? 134.845 151.666 162.928 1.00 86.44  ? 622 VAL D O   1 
ATOM   18744 C CB  . VAL D 1 622 ? 135.578 152.807 166.010 1.00 77.61  ? 622 VAL D CB  1 
ATOM   18745 C CG1 . VAL D 1 622 ? 136.142 151.396 166.004 1.00 74.93  ? 622 VAL D CG1 1 
ATOM   18746 C CG2 . VAL D 1 622 ? 136.657 153.713 166.597 1.00 82.01  ? 622 VAL D CG2 1 
ATOM   18747 N N   . LEU D 1 623 ? 133.016 152.136 164.118 1.00 82.46  ? 623 LEU D N   1 
ATOM   18748 C CA  . LEU D 1 623 ? 132.131 151.276 163.324 1.00 77.19  ? 623 LEU D CA  1 
ATOM   18749 C C   . LEU D 1 623 ? 131.995 151.747 161.863 1.00 81.14  ? 623 LEU D C   1 
ATOM   18750 O O   . LEU D 1 623 ? 132.074 150.926 160.953 1.00 83.16  ? 623 LEU D O   1 
ATOM   18751 C CB  . LEU D 1 623 ? 130.766 151.160 164.022 1.00 80.30  ? 623 LEU D CB  1 
ATOM   18752 C CG  . LEU D 1 623 ? 129.732 150.320 163.253 1.00 84.94  ? 623 LEU D CG  1 
ATOM   18753 C CD1 . LEU D 1 623 ? 130.171 148.872 163.086 1.00 85.90  ? 623 LEU D CD1 1 
ATOM   18754 C CD2 . LEU D 1 623 ? 128.391 150.327 163.974 1.00 84.90  ? 623 LEU D CD2 1 
ATOM   18755 N N   . LEU D 1 624 ? 131.847 153.044 161.596 1.00 82.30  ? 624 LEU D N   1 
ATOM   18756 C CA  . LEU D 1 624 ? 131.859 153.567 160.227 1.00 80.87  ? 624 LEU D CA  1 
ATOM   18757 C C   . LEU D 1 624 ? 133.197 153.327 159.508 1.00 85.10  ? 624 LEU D C   1 
ATOM   18758 O O   . LEU D 1 624 ? 133.175 153.029 158.319 1.00 89.23  ? 624 LEU D O   1 
ATOM   18759 C CB  . LEU D 1 624 ? 131.500 155.059 160.231 1.00 82.26  ? 624 LEU D CB  1 
ATOM   18760 C CG  . LEU D 1 624 ? 130.018 155.339 160.522 1.00 84.71  ? 624 LEU D CG  1 
ATOM   18761 C CD1 . LEU D 1 624 ? 129.821 156.814 160.857 1.00 83.82  ? 624 LEU D CD1 1 
ATOM   18762 C CD2 . LEU D 1 624 ? 129.139 155.006 159.320 1.00 82.11  ? 624 LEU D CD2 1 
ATOM   18763 N N   . LEU D 1 625 ? 134.349 153.390 160.188 1.00 74.77  ? 625 LEU D N   1 
ATOM   18764 C CA  . LEU D 1 625 ? 135.640 153.010 159.609 1.00 69.72  ? 625 LEU D CA  1 
ATOM   18765 C C   . LEU D 1 625 ? 135.705 151.523 159.258 1.00 79.57  ? 625 LEU D C   1 
ATOM   18766 O O   . LEU D 1 625 ? 136.227 151.183 158.203 1.00 89.46  ? 625 LEU D O   1 
ATOM   18767 C CB  . LEU D 1 625 ? 136.791 153.364 160.558 1.00 72.98  ? 625 LEU D CB  1 
ATOM   18768 C CG  . LEU D 1 625 ? 137.215 154.836 160.566 1.00 82.33  ? 625 LEU D CG  1 
ATOM   18769 C CD1 . LEU D 1 625 ? 138.319 155.042 161.587 1.00 77.69  ? 625 LEU D CD1 1 
ATOM   18770 C CD2 . LEU D 1 625 ? 137.764 155.276 159.217 1.00 79.18  ? 625 LEU D CD2 1 
ATOM   18771 N N   . LEU D 1 626 ? 135.154 150.629 160.083 1.00 74.79  ? 626 LEU D N   1 
ATOM   18772 C CA  . LEU D 1 626 ? 135.054 149.209 159.729 1.00 66.02  ? 626 LEU D CA  1 
ATOM   18773 C C   . LEU D 1 626 ? 134.109 148.982 158.552 1.00 68.15  ? 626 LEU D C   1 
ATOM   18774 O O   . LEU D 1 626 ? 134.456 148.247 157.639 1.00 70.25  ? 626 LEU D O   1 
ATOM   18775 C CB  . LEU D 1 626 ? 134.585 148.373 160.922 1.00 66.93  ? 626 LEU D CB  1 
ATOM   18776 C CG  . LEU D 1 626 ? 135.543 148.346 162.112 1.00 71.44  ? 626 LEU D CG  1 
ATOM   18777 C CD1 . LEU D 1 626 ? 134.860 147.639 163.275 1.00 68.35  ? 626 LEU D CD1 1 
ATOM   18778 C CD2 . LEU D 1 626 ? 136.835 147.614 161.771 1.00 67.91  ? 626 LEU D CD2 1 
ATOM   18779 N N   . LEU D 1 627 ? 132.939 149.620 158.520 1.00 71.49  ? 627 LEU D N   1 
ATOM   18780 C CA  . LEU D 1 627 ? 132.001 149.506 157.399 1.00 69.99  ? 627 LEU D CA  1 
ATOM   18781 C C   . LEU D 1 627 ? 132.578 150.083 156.103 1.00 71.65  ? 627 LEU D C   1 
ATOM   18782 O O   . LEU D 1 627 ? 132.392 149.498 155.044 1.00 73.92  ? 627 LEU D O   1 
ATOM   18783 C CB  . LEU D 1 627 ? 130.670 150.183 157.760 1.00 70.80  ? 627 LEU D CB  1 
ATOM   18784 C CG  . LEU D 1 627 ? 129.865 149.449 158.844 1.00 69.43  ? 627 LEU D CG  1 
ATOM   18785 C CD1 . LEU D 1 627 ? 128.683 150.311 159.264 1.00 69.66  ? 627 LEU D CD1 1 
ATOM   18786 C CD2 . LEU D 1 627 ? 129.329 148.114 158.345 1.00 72.81  ? 627 LEU D CD2 1 
ATOM   18787 N N   . ALA D 1 628 ? 133.335 151.178 156.167 1.00 74.27  ? 628 ALA D N   1 
ATOM   18788 C CA  . ALA D 1 628 ? 134.117 151.672 155.041 1.00 66.60  ? 628 ALA D CA  1 
ATOM   18789 C C   . ALA D 1 628 ? 135.176 150.661 154.593 1.00 70.31  ? 628 ALA D C   1 
ATOM   18790 O O   . ALA D 1 628 ? 135.211 150.329 153.413 1.00 76.15  ? 628 ALA D O   1 
ATOM   18791 C CB  . ALA D 1 628 ? 134.741 153.011 155.425 1.00 61.38  ? 628 ALA D CB  1 
ATOM   18792 N N   . TYR D 1 629 ? 135.983 150.088 155.492 1.00 58.50  ? 629 TYR D N   1 
ATOM   18793 C CA  . TYR D 1 629 ? 136.970 149.067 155.119 1.00 56.25  ? 629 TYR D CA  1 
ATOM   18794 C C   . TYR D 1 629 ? 136.323 147.831 154.492 1.00 62.59  ? 629 TYR D C   1 
ATOM   18795 O O   . TYR D 1 629 ? 136.784 147.378 153.446 1.00 73.34  ? 629 TYR D O   1 
ATOM   18796 C CB  . TYR D 1 629 ? 137.835 148.680 156.325 1.00 58.50  ? 629 TYR D CB  1 
ATOM   18797 C CG  . TYR D 1 629 ? 138.705 147.453 156.103 1.00 58.38  ? 629 TYR D CG  1 
ATOM   18798 C CD1 . TYR D 1 629 ? 139.944 147.544 155.434 1.00 54.72  ? 629 TYR D CD1 1 
ATOM   18799 C CD2 . TYR D 1 629 ? 138.244 146.203 156.541 1.00 60.10  ? 629 TYR D CD2 1 
ATOM   18800 C CE1 . TYR D 1 629 ? 140.706 146.384 155.190 1.00 56.62  ? 629 TYR D CE1 1 
ATOM   18801 C CE2 . TYR D 1 629 ? 139.006 145.050 156.306 1.00 67.78  ? 629 TYR D CE2 1 
ATOM   18802 C CZ  . TYR D 1 629 ? 140.234 145.124 155.622 1.00 69.10  ? 629 TYR D CZ  1 
ATOM   18803 O OH  . TYR D 1 629 ? 140.953 143.982 155.424 1.00 58.80  ? 629 TYR D OH  1 
ATOM   18804 N N   . VAL D 1 630 ? 135.250 147.293 155.074 1.00 63.56  ? 630 VAL D N   1 
ATOM   18805 C CA  . VAL D 1 630 ? 134.536 146.110 154.559 1.00 64.99  ? 630 VAL D CA  1 
ATOM   18806 C C   . VAL D 1 630 ? 134.014 146.357 153.157 1.00 62.84  ? 630 VAL D C   1 
ATOM   18807 O O   . VAL D 1 630 ? 134.294 145.582 152.251 1.00 66.65  ? 630 VAL D O   1 
ATOM   18808 C CB  . VAL D 1 630 ? 133.382 145.720 155.500 1.00 64.10  ? 630 VAL D CB  1 
ATOM   18809 C CG1 . VAL D 1 630 ? 132.411 144.704 154.894 1.00 61.26  ? 630 VAL D CG1 1 
ATOM   18810 C CG2 . VAL D 1 630 ? 133.934 145.082 156.768 1.00 63.37  ? 630 VAL D CG2 1 
ATOM   18811 N N   . LEU D 1 631 ? 133.279 147.450 152.940 1.00 66.46  ? 631 LEU D N   1 
ATOM   18812 C CA  . LEU D 1 631 ? 132.701 147.748 151.641 1.00 65.30  ? 631 LEU D CA  1 
ATOM   18813 C C   . LEU D 1 631 ? 133.786 147.988 150.596 1.00 66.00  ? 631 LEU D C   1 
ATOM   18814 O O   . LEU D 1 631 ? 133.745 147.365 149.542 1.00 70.06  ? 631 LEU D O   1 
ATOM   18815 C CB  . LEU D 1 631 ? 131.722 148.924 151.781 1.00 65.07  ? 631 LEU D CB  1 
ATOM   18816 C CG  . LEU D 1 631 ? 130.463 148.577 152.599 1.00 67.40  ? 631 LEU D CG  1 
ATOM   18817 C CD1 . LEU D 1 631 ? 129.651 149.837 152.862 1.00 69.73  ? 631 LEU D CD1 1 
ATOM   18818 C CD2 . LEU D 1 631 ? 129.555 147.595 151.872 1.00 65.19  ? 631 LEU D CD2 1 
ATOM   18819 N N   . LEU D 1 632 ? 134.812 148.793 150.886 1.00 67.20  ? 632 LEU D N   1 
ATOM   18820 C CA  . LEU D 1 632 ? 135.917 149.012 149.954 1.00 60.01  ? 632 LEU D CA  1 
ATOM   18821 C C   . LEU D 1 632 ? 136.691 147.733 149.641 1.00 58.09  ? 632 LEU D C   1 
ATOM   18822 O O   . LEU D 1 632 ? 137.018 147.485 148.486 1.00 68.09  ? 632 LEU D O   1 
ATOM   18823 C CB  . LEU D 1 632 ? 136.869 150.073 150.516 1.00 60.36  ? 632 LEU D CB  1 
ATOM   18824 C CG  . LEU D 1 632 ? 136.286 151.492 150.567 1.00 64.17  ? 632 LEU D CG  1 
ATOM   18825 C CD1 . LEU D 1 632 ? 137.344 152.425 151.144 1.00 65.19  ? 632 LEU D CD1 1 
ATOM   18826 C CD2 . LEU D 1 632 ? 135.901 152.012 149.188 1.00 64.52  ? 632 LEU D CD2 1 
ATOM   18827 N N   . THR D 1 633 ? 136.960 146.895 150.633 1.00 59.95  ? 633 THR D N   1 
ATOM   18828 C CA  . THR D 1 633 ? 137.670 145.621 150.463 1.00 62.05  ? 633 THR D CA  1 
ATOM   18829 C C   . THR D 1 633 ? 136.854 144.599 149.686 1.00 63.65  ? 633 THR D C   1 
ATOM   18830 O O   . THR D 1 633 ? 137.411 143.875 148.876 1.00 62.93  ? 633 THR D O   1 
ATOM   18831 C CB  . THR D 1 633 ? 138.046 145.039 151.825 1.00 57.87  ? 633 THR D CB  1 
ATOM   18832 O OG1 . THR D 1 633 ? 138.898 145.946 152.460 1.00 66.25  ? 633 THR D OG1 1 
ATOM   18833 C CG2 . THR D 1 633 ? 138.772 143.704 151.757 1.00 62.48  ? 633 THR D CG2 1 
ATOM   18834 N N   . TYR D 1 634 ? 135.541 144.513 149.883 1.00 73.12  ? 634 TYR D N   1 
ATOM   18835 C CA  . TYR D 1 634 ? 134.720 143.539 149.168 1.00 59.43  ? 634 TYR D CA  1 
ATOM   18836 C C   . TYR D 1 634 ? 134.444 144.004 147.733 1.00 65.11  ? 634 TYR D C   1 
ATOM   18837 O O   . TYR D 1 634 ? 134.449 143.179 146.830 1.00 71.64  ? 634 TYR D O   1 
ATOM   18838 C CB  . TYR D 1 634 ? 133.451 143.218 149.971 1.00 65.97  ? 634 TYR D CB  1 
ATOM   18839 C CG  . TYR D 1 634 ? 133.629 142.305 151.188 1.00 83.64  ? 634 TYR D CG  1 
ATOM   18840 C CD1 . TYR D 1 634 ? 134.853 142.192 151.881 1.00 81.25  ? 634 TYR D CD1 1 
ATOM   18841 C CD2 . TYR D 1 634 ? 132.539 141.531 151.624 1.00 73.69  ? 634 TYR D CD2 1 
ATOM   18842 C CE1 . TYR D 1 634 ? 134.992 141.329 152.977 1.00 73.79  ? 634 TYR D CE1 1 
ATOM   18843 C CE2 . TYR D 1 634 ? 132.677 140.660 152.717 1.00 71.23  ? 634 TYR D CE2 1 
ATOM   18844 C CZ  . TYR D 1 634 ? 133.908 140.553 153.400 1.00 74.15  ? 634 TYR D CZ  1 
ATOM   18845 O OH  . TYR D 1 634 ? 134.041 139.699 154.451 1.00 78.69  ? 634 TYR D OH  1 
ATOM   18846 N N   . VAL D 1 635 ? 134.339 145.310 147.468 1.00 68.64  ? 635 VAL D N   1 
ATOM   18847 C CA  . VAL D 1 635 ? 134.406 145.879 146.112 1.00 59.30  ? 635 VAL D CA  1 
ATOM   18848 C C   . VAL D 1 635 ? 135.754 145.578 145.446 1.00 59.44  ? 635 VAL D C   1 
ATOM   18849 O O   . VAL D 1 635 ? 135.781 145.160 144.295 1.00 68.21  ? 635 VAL D O   1 
ATOM   18850 C CB  . VAL D 1 635 ? 134.138 147.394 146.144 1.00 58.68  ? 635 VAL D CB  1 
ATOM   18851 C CG1 . VAL D 1 635 ? 134.345 148.079 144.795 1.00 67.70  ? 635 VAL D CG1 1 
ATOM   18852 C CG2 . VAL D 1 635 ? 132.693 147.677 146.541 1.00 58.60  ? 635 VAL D CG2 1 
ATOM   18853 N N   . LEU D 1 636 ? 136.879 145.723 146.152 1.00 52.16  ? 636 LEU D N   1 
ATOM   18854 C CA  . LEU D 1 636 ? 138.202 145.360 145.643 1.00 53.13  ? 636 LEU D CA  1 
ATOM   18855 C C   . LEU D 1 636 ? 138.321 143.859 145.342 1.00 60.50  ? 636 LEU D C   1 
ATOM   18856 O O   . LEU D 1 636 ? 138.800 143.511 144.268 1.00 71.99  ? 636 LEU D O   1 
ATOM   18857 C CB  . LEU D 1 636 ? 139.270 145.841 146.635 1.00 64.45  ? 636 LEU D CB  1 
ATOM   18858 C CG  . LEU D 1 636 ? 140.701 145.386 146.319 1.00 69.83  ? 636 LEU D CG  1 
ATOM   18859 C CD1 . LEU D 1 636 ? 141.231 146.023 145.040 1.00 61.35  ? 636 LEU D CD1 1 
ATOM   18860 C CD2 . LEU D 1 636 ? 141.620 145.734 147.482 1.00 62.85  ? 636 LEU D CD2 1 
ATOM   18861 N N   . LEU D 1 637 ? 137.890 142.961 146.222 1.00 62.63  ? 637 LEU D N   1 
ATOM   18862 C CA  . LEU D 1 637 ? 137.921 141.515 145.968 1.00 58.81  ? 637 LEU D CA  1 
ATOM   18863 C C   . LEU D 1 637 ? 137.015 141.129 144.795 1.00 58.59  ? 637 LEU D C   1 
ATOM   18864 O O   . LEU D 1 637 ? 137.385 140.288 143.995 1.00 63.27  ? 637 LEU D O   1 
ATOM   18865 C CB  . LEU D 1 637 ? 137.532 140.740 147.235 1.00 65.31  ? 637 LEU D CB  1 
ATOM   18866 C CG  . LEU D 1 637 ? 138.567 140.784 148.371 1.00 68.45  ? 637 LEU D CG  1 
ATOM   18867 C CD1 . LEU D 1 637 ? 137.978 140.170 149.637 1.00 65.09  ? 637 LEU D CD1 1 
ATOM   18868 C CD2 . LEU D 1 637 ? 139.834 140.012 148.024 1.00 65.47  ? 637 LEU D CD2 1 
ATOM   18869 N N   . LEU D 1 638 ? 135.858 141.771 144.643 1.00 67.72  ? 638 LEU D N   1 
ATOM   18870 C CA  . LEU D 1 638 ? 134.946 141.599 143.517 1.00 61.59  ? 638 LEU D CA  1 
ATOM   18871 C C   . LEU D 1 638 ? 135.564 142.082 142.192 1.00 62.02  ? 638 LEU D C   1 
ATOM   18872 O O   . LEU D 1 638 ? 135.548 141.346 141.213 1.00 63.36  ? 638 LEU D O   1 
ATOM   18873 C CB  . LEU D 1 638 ? 133.651 142.326 143.906 1.00 62.84  ? 638 LEU D CB  1 
ATOM   18874 C CG  . LEU D 1 638 ? 132.457 142.234 142.958 1.00 65.56  ? 638 LEU D CG  1 
ATOM   18875 C CD1 . LEU D 1 638 ? 131.990 140.796 142.775 1.00 62.24  ? 638 LEU D CD1 1 
ATOM   18876 C CD2 . LEU D 1 638 ? 131.325 143.048 143.577 1.00 64.21  ? 638 LEU D CD2 1 
ATOM   18877 N N   . ASN D 1 639 ? 136.211 143.251 142.173 1.00 73.09  ? 639 ASN D N   1 
ATOM   18878 C CA  . ASN D 1 639 ? 137.027 143.721 141.049 1.00 63.16  ? 639 ASN D CA  1 
ATOM   18879 C C   . ASN D 1 639 ? 138.176 142.756 140.726 1.00 64.07  ? 639 ASN D C   1 
ATOM   18880 O O   . ASN D 1 639 ? 138.436 142.489 139.559 1.00 75.44  ? 639 ASN D O   1 
ATOM   18881 C CB  . ASN D 1 639 ? 137.632 145.104 141.350 1.00 57.18  ? 639 ASN D CB  1 
ATOM   18882 C CG  . ASN D 1 639 ? 136.673 146.276 141.419 1.00 66.19  ? 639 ASN D CG  1 
ATOM   18883 O OD1 . ASN D 1 639 ? 135.528 146.219 141.022 1.00 68.69  ? 639 ASN D OD1 1 
ATOM   18884 N ND2 . ASN D 1 639 ? 137.119 147.401 141.922 1.00 68.68  ? 639 ASN D ND2 1 
ATOM   18885 N N   . MET D 1 640 ? 138.870 142.225 141.733 1.00 59.81  ? 640 MET D N   1 
ATOM   18886 C CA  . MET D 1 640 ? 140.002 141.316 141.567 1.00 59.69  ? 640 MET D CA  1 
ATOM   18887 C C   . MET D 1 640 ? 139.593 139.966 140.971 1.00 68.16  ? 640 MET D C   1 
ATOM   18888 O O   . MET D 1 640 ? 140.190 139.543 139.990 1.00 70.22  ? 640 MET D O   1 
ATOM   18889 C CB  . MET D 1 640 ? 140.717 141.174 142.916 1.00 65.54  ? 640 MET D CB  1 
ATOM   18890 C CG  . MET D 1 640 ? 141.983 140.314 142.872 1.00 69.39  ? 640 MET D CG  1 
ATOM   18891 S SD  . MET D 1 640 ? 141.819 138.564 143.287 1.00 82.07  ? 640 MET D SD  1 
ATOM   18892 C CE  . MET D 1 640 ? 141.385 138.651 145.040 1.00 66.57  ? 640 MET D CE  1 
ATOM   18893 N N   . LEU D 1 641 ? 138.531 139.327 141.468 1.00 72.65  ? 641 LEU D N   1 
ATOM   18894 C CA  . LEU D 1 641 ? 138.017 138.069 140.915 1.00 64.10  ? 641 LEU D CA  1 
ATOM   18895 C C   . LEU D 1 641 ? 137.525 138.244 139.478 1.00 61.28  ? 641 LEU D C   1 
ATOM   18896 O O   . LEU D 1 641 ? 137.849 137.436 138.616 1.00 69.04  ? 641 LEU D O   1 
ATOM   18897 C CB  . LEU D 1 641 ? 136.891 137.528 141.813 1.00 70.89  ? 641 LEU D CB  1 
ATOM   18898 C CG  . LEU D 1 641 ? 137.351 136.464 142.824 1.00 72.69  ? 641 LEU D CG  1 
ATOM   18899 C CD1 . LEU D 1 641 ? 138.461 136.924 143.759 1.00 63.71  ? 641 LEU D CD1 1 
ATOM   18900 C CD2 . LEU D 1 641 ? 136.163 136.053 143.688 1.00 73.43  ? 641 LEU D CD2 1 
ATOM   18901 N N   . ILE D 1 642 ? 136.775 139.300 139.184 1.00 67.07  ? 642 ILE D N   1 
ATOM   18902 C CA  . ILE D 1 642 ? 136.279 139.573 137.830 1.00 67.49  ? 642 ILE D CA  1 
ATOM   18903 C C   . ILE D 1 642 ? 137.410 139.929 136.863 1.00 67.35  ? 642 ILE D C   1 
ATOM   18904 O O   . ILE D 1 642 ? 137.395 139.460 135.727 1.00 76.05  ? 642 ILE D O   1 
ATOM   18905 C CB  . ILE D 1 642 ? 135.154 140.623 137.908 1.00 68.91  ? 642 ILE D CB  1 
ATOM   18906 C CG1 . ILE D 1 642 ? 133.876 139.912 138.411 1.00 66.91  ? 642 ILE D CG1 1 
ATOM   18907 C CG2 . ILE D 1 642 ? 134.892 141.301 136.563 1.00 65.81  ? 642 ILE D CG2 1 
ATOM   18908 C CD1 . ILE D 1 642 ? 132.799 140.843 138.955 1.00 67.10  ? 642 ILE D CD1 1 
ATOM   18909 N N   . ALA D 1 643 ? 138.433 140.678 137.285 1.00 65.94  ? 643 ALA D N   1 
ATOM   18910 C CA  . ALA D 1 643 ? 139.631 140.916 136.485 1.00 61.18  ? 643 ALA D CA  1 
ATOM   18911 C C   . ALA D 1 643 ? 140.357 139.602 136.146 1.00 70.60  ? 643 ALA D C   1 
ATOM   18912 O O   . ALA D 1 643 ? 140.627 139.352 134.974 1.00 80.51  ? 643 ALA D O   1 
ATOM   18913 C CB  . ALA D 1 643 ? 140.539 141.901 137.218 1.00 57.77  ? 643 ALA D CB  1 
ATOM   18914 N N   . LEU D 1 644 ? 140.587 138.720 137.122 1.00 78.52  ? 644 LEU D N   1 
ATOM   18915 C CA  . LEU D 1 644 ? 141.176 137.396 136.906 1.00 69.82  ? 644 LEU D CA  1 
ATOM   18916 C C   . LEU D 1 644 ? 140.340 136.525 135.964 1.00 69.75  ? 644 LEU D C   1 
ATOM   18917 O O   . LEU D 1 644 ? 140.901 135.951 135.036 1.00 82.17  ? 644 LEU D O   1 
ATOM   18918 C CB  . LEU D 1 644 ? 141.368 136.686 138.254 1.00 72.86  ? 644 LEU D CB  1 
ATOM   18919 C CG  . LEU D 1 644 ? 142.783 136.798 138.838 1.00 77.22  ? 644 LEU D CG  1 
ATOM   18920 C CD1 . LEU D 1 644 ? 143.291 138.226 138.997 1.00 78.40  ? 644 LEU D CD1 1 
ATOM   18921 C CD2 . LEU D 1 644 ? 142.784 136.155 140.216 1.00 78.76  ? 644 LEU D CD2 1 
ATOM   18922 N N   . MET D 1 645 ? 139.019 136.436 136.133 1.00 72.92  ? 645 MET D N   1 
ATOM   18923 C CA  . MET D 1 645 ? 138.157 135.709 135.190 1.00 76.95  ? 645 MET D CA  1 
ATOM   18924 C C   . MET D 1 645 ? 138.271 136.263 133.773 1.00 81.17  ? 645 MET D C   1 
ATOM   18925 O O   . MET D 1 645 ? 138.401 135.495 132.831 1.00 83.06  ? 645 MET D O   1 
ATOM   18926 C CB  . MET D 1 645 ? 136.691 135.767 135.619 1.00 74.40  ? 645 MET D CB  1 
ATOM   18927 C CG  . MET D 1 645 ? 136.416 134.963 136.883 1.00 81.85  ? 645 MET D CG  1 
ATOM   18928 S SD  . MET D 1 645 ? 134.722 135.154 137.467 1.00 94.00  ? 645 MET D SD  1 
ATOM   18929 C CE  . MET D 1 645 ? 134.968 134.535 139.148 1.00 82.05  ? 645 MET D CE  1 
ATOM   18930 N N   . SER D 1 646 ? 138.272 137.584 133.603 1.00 81.89  ? 646 SER D N   1 
ATOM   18931 C CA  . SER D 1 646 ? 138.343 138.196 132.276 1.00 81.03  ? 646 SER D CA  1 
ATOM   18932 C C   . SER D 1 646 ? 139.613 137.825 131.493 1.00 85.15  ? 646 SER D C   1 
ATOM   18933 O O   . SER D 1 646 ? 139.529 137.622 130.284 1.00 87.16  ? 646 SER D O   1 
ATOM   18934 C CB  . SER D 1 646 ? 138.171 139.712 132.383 1.00 76.66  ? 646 SER D CB  1 
ATOM   18935 O OG  . SER D 1 646 ? 139.351 140.368 132.808 1.00 78.96  ? 646 SER D OG  1 
ATOM   18936 N N   . GLU D 1 647 ? 140.778 137.681 132.139 1.00 90.30  ? 647 GLU D N   1 
ATOM   18937 C CA  . GLU D 1 647 ? 141.999 137.246 131.446 1.00 92.76  ? 647 GLU D CA  1 
ATOM   18938 C C   . GLU D 1 647 ? 142.124 135.719 131.338 1.00 94.62  ? 647 GLU D C   1 
ATOM   18939 O O   . GLU D 1 647 ? 142.553 135.213 130.304 1.00 99.01  ? 647 GLU D O   1 
ATOM   18940 C CB  . GLU D 1 647 ? 143.247 137.876 132.088 1.00 92.30  ? 647 GLU D CB  1 
ATOM   18941 C CG  . GLU D 1 647 ? 144.513 137.555 131.257 1.00 101.30 ? 647 GLU D CG  1 
ATOM   18942 C CD  . GLU D 1 647 ? 145.710 138.500 131.471 1.00 103.04 ? 647 GLU D CD  1 
ATOM   18943 O OE1 . GLU D 1 647 ? 145.545 139.625 131.986 1.00 98.81  ? 647 GLU D OE1 1 
ATOM   18944 O OE2 . GLU D 1 647 ? 146.857 138.129 131.146 1.00 99.26  ? 647 GLU D OE2 1 
ATOM   18945 N N   . THR D 1 648 ? 141.763 134.971 132.379 1.00 78.23  ? 648 THR D N   1 
ATOM   18946 C CA  . THR D 1 648 ? 142.023 133.521 132.462 1.00 80.26  ? 648 THR D CA  1 
ATOM   18947 C C   . THR D 1 648 ? 140.908 132.621 131.913 1.00 80.71  ? 648 THR D C   1 
ATOM   18948 O O   . THR D 1 648 ? 141.186 131.476 131.571 1.00 81.80  ? 648 THR D O   1 
ATOM   18949 C CB  . THR D 1 648 ? 142.357 133.092 133.897 1.00 78.59  ? 648 THR D CB  1 
ATOM   18950 O OG1 . THR D 1 648 ? 141.281 133.349 134.755 1.00 81.80  ? 648 THR D OG1 1 
ATOM   18951 C CG2 . THR D 1 648 ? 143.589 133.778 134.477 1.00 75.32  ? 648 THR D CG2 1 
ATOM   18952 N N   . VAL D 1 649 ? 139.663 133.091 131.793 1.00 82.30  ? 649 VAL D N   1 
ATOM   18953 C CA  . VAL D 1 649 ? 138.547 132.289 131.215 1.00 83.41  ? 649 VAL D CA  1 
ATOM   18954 C C   . VAL D 1 649 ? 138.388 132.781 129.782 1.00 87.67  ? 649 VAL D C   1 
ATOM   18955 O O   . VAL D 1 649 ? 137.402 133.493 129.503 1.00 87.26  ? 649 VAL D O   1 
ATOM   18956 C CB  . VAL D 1 649 ? 137.248 132.446 132.029 1.00 79.62  ? 649 VAL D CB  1 
ATOM   18957 C CG1 . VAL D 1 649 ? 136.159 131.503 131.538 1.00 79.31  ? 649 VAL D CG1 1 
ATOM   18958 C CG2 . VAL D 1 649 ? 137.493 132.246 133.517 1.00 80.95  ? 649 VAL D CG2 1 
ATOM   18959 N N   . ASN D 1 650 ? 139.337 132.427 128.918 1.00 90.51  ? 650 ASN D N   1 
ATOM   18960 C CA  . ASN D 1 650 ? 139.313 132.993 127.546 1.00 87.40  ? 650 ASN D CA  1 
ATOM   18961 C C   . ASN D 1 650 ? 138.902 131.950 126.504 1.00 86.89  ? 650 ASN D C   1 
ATOM   18962 O O   . ASN D 1 650 ? 138.733 132.376 125.344 1.00 84.00  ? 650 ASN D O   1 
ATOM   18963 C CB  . ASN D 1 650 ? 140.667 133.609 127.186 1.00 90.41  ? 650 ASN D CB  1 
ATOM   18964 C CG  . ASN D 1 650 ? 141.822 132.661 127.430 1.00 94.30  ? 650 ASN D CG  1 
ATOM   18965 O OD1 . ASN D 1 650 ? 141.620 131.463 127.615 1.00 97.53  ? 650 ASN D OD1 1 
ATOM   18966 N ND2 . ASN D 1 650 ? 143.036 133.187 127.431 1.00 89.13  ? 650 ASN D ND2 1 
ATOM   18967 N N   . HIS D 1 651 ? 138.776 130.671 126.838 1.00 92.25  ? 651 HIS D N   1 
ATOM   18968 C CA  . HIS D 1 651 ? 138.473 129.614 125.830 1.00 93.13  ? 651 HIS D CA  1 
ATOM   18969 C C   . HIS D 1 651 ? 139.713 129.101 125.092 1.00 93.03  ? 651 HIS D C   1 
ATOM   18970 O O   . HIS D 1 651 ? 139.551 128.150 124.331 1.00 88.40  ? 651 HIS D O   1 
ATOM   18971 C CB  . HIS D 1 651 ? 137.307 130.060 124.940 1.00 91.15  ? 651 HIS D CB  1 
ATOM   18972 C CG  . HIS D 1 651 ? 136.062 130.358 125.704 1.00 91.91  ? 651 HIS D CG  1 
ATOM   18973 N ND1 . HIS D 1 651 ? 135.516 129.469 126.600 1.00 90.52  ? 651 HIS D ND1 1 
ATOM   18974 C CD2 . HIS D 1 651 ? 135.259 131.440 125.712 1.00 92.65  ? 651 HIS D CD2 1 
ATOM   18975 C CE1 . HIS D 1 651 ? 134.435 129.996 127.132 1.00 90.40  ? 651 HIS D CE1 1 
ATOM   18976 N NE2 . HIS D 1 651 ? 134.254 131.201 126.603 1.00 87.23  ? 651 HIS D NE2 1 
ATOM   18977 N N   . VAL D 1 652 ? 140.895 129.689 125.300 1.00 102.31 ? 652 VAL D N   1 
ATOM   18978 C CA  . VAL D 1 652 ? 142.121 129.129 124.717 1.00 98.34  ? 652 VAL D CA  1 
ATOM   18979 C C   . VAL D 1 652 ? 142.163 127.628 125.028 1.00 99.19  ? 652 VAL D C   1 
ATOM   18980 O O   . VAL D 1 652 ? 141.902 127.222 126.159 1.00 98.23  ? 652 VAL D O   1 
ATOM   18981 C CB  . VAL D 1 652 ? 143.365 129.861 125.251 1.00 96.77  ? 652 VAL D CB  1 
ATOM   18982 C CG1 . VAL D 1 652 ? 144.674 129.217 124.781 1.00 97.31  ? 652 VAL D CG1 1 
ATOM   18983 C CG2 . VAL D 1 652 ? 143.389 131.315 124.774 1.00 96.64  ? 652 VAL D CG2 1 
ATOM   18984 N N   . ALA D 1 653 ? 142.457 126.790 124.033 1.00 108.54 ? 653 ALA D N   1 
ATOM   18985 C CA  . ALA D 1 653 ? 142.511 125.340 124.208 1.00 108.60 ? 653 ALA D CA  1 
ATOM   18986 C C   . ALA D 1 653 ? 143.630 124.944 125.184 1.00 107.17 ? 653 ALA D C   1 
ATOM   18987 O O   . ALA D 1 653 ? 144.716 125.520 125.155 1.00 105.39 ? 653 ALA D O   1 
ATOM   18988 C CB  . ALA D 1 653 ? 142.682 124.684 122.836 1.00 106.05 ? 653 ALA D CB  1 
ATOM   18989 N N   . ASP D 1 654 ? 143.376 123.976 126.062 1.00 106.66 ? 654 ASP D N   1 
ATOM   18990 C CA  . ASP D 1 654 ? 144.233 123.733 127.223 1.00 105.79 ? 654 ASP D CA  1 
ATOM   18991 C C   . ASP D 1 654 ? 145.649 123.252 126.835 1.00 106.70 ? 654 ASP D C   1 
ATOM   18992 O O   . ASP D 1 654 ? 145.823 122.177 126.260 1.00 100.92 ? 654 ASP D O   1 
ATOM   18993 C CB  . ASP D 1 654 ? 143.533 122.751 128.174 1.00 106.60 ? 654 ASP D CB  1 
ATOM   18994 C CG  . ASP D 1 654 ? 144.264 122.594 129.513 1.00 109.56 ? 654 ASP D CG  1 
ATOM   18995 O OD1 . ASP D 1 654 ? 145.212 123.360 129.787 1.00 108.24 ? 654 ASP D OD1 1 
ATOM   18996 O OD2 . ASP D 1 654 ? 143.926 121.673 130.286 1.00 107.00 ? 654 ASP D OD2 1 
ATOM   18997 N N   . ASN D 1 655 ? 146.682 124.034 127.192 1.00 104.95 ? 655 ASN D N   1 
ATOM   18998 C CA  . ASN D 1 655 ? 148.088 123.696 126.802 1.00 102.07 ? 655 ASN D CA  1 
ATOM   18999 C C   . ASN D 1 655 ? 148.843 123.039 127.965 1.00 104.20 ? 655 ASN D C   1 
ATOM   19000 O O   . ASN D 1 655 ? 150.082 123.170 128.000 1.00 105.89 ? 655 ASN D O   1 
ATOM   19001 C CB  . ASN D 1 655 ? 148.841 124.926 126.287 1.00 101.08 ? 655 ASN D CB  1 
ATOM   19002 C CG  . ASN D 1 655 ? 148.241 125.500 125.021 1.00 109.41 ? 655 ASN D CG  1 
ATOM   19003 O OD1 . ASN D 1 655 ? 148.633 126.577 124.576 1.00 109.61 ? 655 ASN D OD1 1 
ATOM   19004 N ND2 . ASN D 1 655 ? 147.291 124.791 124.434 1.00 110.97 ? 655 ASN D ND2 1 
ATOM   19005 N N   . SER D 1 656 ? 148.140 122.353 128.865 1.00 95.66  ? 656 SER D N   1 
ATOM   19006 C CA  . SER D 1 656 ? 148.716 121.661 130.016 1.00 89.24  ? 656 SER D CA  1 
ATOM   19007 C C   . SER D 1 656 ? 149.408 120.332 129.718 1.00 90.27  ? 656 SER D C   1 
ATOM   19008 O O   . SER D 1 656 ? 150.454 120.076 130.306 1.00 95.03  ? 656 SER D O   1 
ATOM   19009 C CB  . SER D 1 656 ? 147.649 121.444 131.086 1.00 93.22  ? 656 SER D CB  1 
ATOM   19010 O OG  . SER D 1 656 ? 146.620 120.638 130.564 1.00 98.66  ? 656 SER D OG  1 
ATOM   19011 N N   . TRP D 1 657 ? 148.923 119.516 128.782 1.00 82.07  ? 657 TRP D N   1 
ATOM   19012 C CA  . TRP D 1 657 ? 149.607 118.277 128.376 1.00 85.23  ? 657 TRP D CA  1 
ATOM   19013 C C   . TRP D 1 657 ? 151.019 118.535 127.846 1.00 84.90  ? 657 TRP D C   1 
ATOM   19014 O O   . TRP D 1 657 ? 151.972 117.853 128.204 1.00 89.28  ? 657 TRP D O   1 
ATOM   19015 C CB  . TRP D 1 657 ? 148.747 117.539 127.348 1.00 81.06  ? 657 TRP D CB  1 
ATOM   19016 C CG  . TRP D 1 657 ? 149.403 116.376 126.669 1.00 84.50  ? 657 TRP D CG  1 
ATOM   19017 C CD1 . TRP D 1 657 ? 149.453 115.107 127.132 1.00 85.70  ? 657 TRP D CD1 1 
ATOM   19018 C CD2 . TRP D 1 657 ? 150.118 116.355 125.397 1.00 90.69  ? 657 TRP D CD2 1 
ATOM   19019 N NE1 . TRP D 1 657 ? 150.156 114.313 126.251 1.00 84.29  ? 657 TRP D NE1 1 
ATOM   19020 C CE2 . TRP D 1 657 ? 150.589 115.031 125.161 1.00 90.65  ? 657 TRP D CE2 1 
ATOM   19021 C CE3 . TRP D 1 657 ? 150.380 117.317 124.398 1.00 88.55  ? 657 TRP D CE3 1 
ATOM   19022 C CZ2 . TRP D 1 657 ? 151.300 114.686 124.004 1.00 85.72  ? 657 TRP D CZ2 1 
ATOM   19023 C CZ3 . TRP D 1 657 ? 151.092 116.979 123.236 1.00 85.60  ? 657 TRP D CZ3 1 
ATOM   19024 C CH2 . TRP D 1 657 ? 151.561 115.669 123.038 1.00 82.60  ? 657 TRP D CH2 1 
ATOM   19025 N N   . SER D 1 658 ? 151.184 119.585 127.052 1.00 77.42  ? 658 SER D N   1 
ATOM   19026 C CA  . SER D 1 658 ? 152.473 119.972 126.464 1.00 69.87  ? 658 SER D CA  1 
ATOM   19027 C C   . SER D 1 658 ? 153.407 120.651 127.468 1.00 76.28  ? 658 SER D C   1 
ATOM   19028 O O   . SER D 1 658 ? 154.617 120.463 127.405 1.00 83.36  ? 658 SER D O   1 
ATOM   19029 C CB  . SER D 1 658 ? 152.253 120.827 125.217 1.00 70.74  ? 658 SER D CB  1 
ATOM   19030 O OG  . SER D 1 658 ? 151.779 122.119 125.531 1.00 80.87  ? 658 SER D OG  1 
ATOM   19031 N N   . ILE D 1 659 ? 152.884 121.436 128.405 1.00 69.80  ? 659 ILE D N   1 
ATOM   19032 C CA  . ILE D 1 659 ? 153.706 122.006 129.478 1.00 67.00  ? 659 ILE D CA  1 
ATOM   19033 C C   . ILE D 1 659 ? 154.156 120.886 130.424 1.00 66.86  ? 659 ILE D C   1 
ATOM   19034 O O   . ILE D 1 659 ? 155.303 120.875 130.855 1.00 75.38  ? 659 ILE D O   1 
ATOM   19035 C CB  . ILE D 1 659 ? 152.962 123.161 130.168 1.00 69.70  ? 659 ILE D CB  1 
ATOM   19036 C CG1 . ILE D 1 659 ? 152.771 124.348 129.213 1.00 70.18  ? 659 ILE D CG1 1 
ATOM   19037 C CG2 . ILE D 1 659 ? 153.705 123.614 131.434 1.00 71.87  ? 659 ILE D CG2 1 
ATOM   19038 C CD1 . ILE D 1 659 ? 151.790 125.402 129.719 1.00 69.77  ? 659 ILE D CD1 1 
ATOM   19039 N N   . TRP D 1 660 ? 153.330 119.870 130.665 1.00 57.69  ? 660 TRP D N   1 
ATOM   19040 C CA  . TRP D 1 660 ? 153.743 118.658 131.364 1.00 62.85  ? 660 TRP D CA  1 
ATOM   19041 C C   . TRP D 1 660 ? 154.802 117.853 130.601 1.00 66.83  ? 660 TRP D C   1 
ATOM   19042 O O   . TRP D 1 660 ? 155.801 117.448 131.186 1.00 76.34  ? 660 TRP D O   1 
ATOM   19043 C CB  . TRP D 1 660 ? 152.511 117.821 131.684 1.00 66.34  ? 660 TRP D CB  1 
ATOM   19044 C CG  . TRP D 1 660 ? 152.822 116.460 132.200 1.00 65.92  ? 660 TRP D CG  1 
ATOM   19045 C CD1 . TRP D 1 660 ? 153.486 116.189 133.341 1.00 62.83  ? 660 TRP D CD1 1 
ATOM   19046 C CD2 . TRP D 1 660 ? 152.577 115.175 131.563 1.00 64.71  ? 660 TRP D CD2 1 
ATOM   19047 N NE1 . TRP D 1 660 ? 153.643 114.828 133.467 1.00 55.94  ? 660 TRP D NE1 1 
ATOM   19048 C CE2 . TRP D 1 660 ? 153.090 114.154 132.407 1.00 63.10  ? 660 TRP D CE2 1 
ATOM   19049 C CE3 . TRP D 1 660 ? 151.982 114.774 130.353 1.00 69.52  ? 660 TRP D CE3 1 
ATOM   19050 C CZ2 . TRP D 1 660 ? 152.990 112.796 132.084 1.00 67.17  ? 660 TRP D CZ2 1 
ATOM   19051 C CZ3 . TRP D 1 660 ? 151.891 113.418 130.009 1.00 70.23  ? 660 TRP D CZ3 1 
ATOM   19052 C CH2 . TRP D 1 660 ? 152.386 112.430 130.873 1.00 68.36  ? 660 TRP D CH2 1 
ATOM   19053 N N   . LYS D 1 661 ? 154.683 117.682 129.283 1.00 67.28  ? 661 LYS D N   1 
ATOM   19054 C CA  . LYS D 1 661 ? 155.738 117.082 128.449 1.00 60.71  ? 661 LYS D CA  1 
ATOM   19055 C C   . LYS D 1 661 ? 157.063 117.838 128.539 1.00 62.82  ? 661 LYS D C   1 
ATOM   19056 O O   . LYS D 1 661 ? 158.108 117.204 128.583 1.00 65.99  ? 661 LYS D O   1 
ATOM   19057 C CB  . LYS D 1 661 ? 155.262 117.010 126.995 1.00 58.01  ? 661 LYS D CB  1 
ATOM   19058 C CG  . LYS D 1 661 ? 154.267 115.872 126.739 1.00 62.18  ? 661 LYS D CG  1 
ATOM   19059 C CD  . LYS D 1 661 ? 154.997 114.572 126.397 1.00 70.03  ? 661 LYS D CD  1 
ATOM   19060 C CE  . LYS D 1 661 ? 153.993 113.475 126.048 1.00 74.58  ? 661 LYS D CE  1 
ATOM   19061 N NZ  . LYS D 1 661 ? 154.646 112.334 125.358 1.00 67.90  ? 661 LYS D NZ  1 
ATOM   19062 N N   . LEU D 1 662 ? 157.062 119.167 128.641 1.00 58.00  ? 662 LEU D N   1 
ATOM   19063 C CA  . LEU D 1 662 ? 158.272 119.954 128.895 1.00 52.44  ? 662 LEU D CA  1 
ATOM   19064 C C   . LEU D 1 662 ? 158.829 119.744 130.306 1.00 68.79  ? 662 LEU D C   1 
ATOM   19065 O O   . LEU D 1 662 ? 160.037 119.612 130.465 1.00 78.01  ? 662 LEU D O   1 
ATOM   19066 C CB  . LEU D 1 662 ? 157.973 121.430 128.593 1.00 52.82  ? 662 LEU D CB  1 
ATOM   19067 C CG  . LEU D 1 662 ? 159.146 122.394 128.829 1.00 58.93  ? 662 LEU D CG  1 
ATOM   19068 C CD1 . LEU D 1 662 ? 160.299 122.187 127.857 1.00 62.25  ? 662 LEU D CD1 1 
ATOM   19069 C CD2 . LEU D 1 662 ? 158.651 123.820 128.671 1.00 62.21  ? 662 LEU D CD2 1 
ATOM   19070 N N   . GLN D 1 663 ? 157.990 119.642 131.335 1.00 62.30  ? 663 GLN D N   1 
ATOM   19071 C CA  . GLN D 1 663 ? 158.433 119.298 132.686 1.00 44.14  ? 663 GLN D CA  1 
ATOM   19072 C C   . GLN D 1 663 ? 159.118 117.930 132.726 1.00 59.13  ? 663 GLN D C   1 
ATOM   19073 O O   . GLN D 1 663 ? 160.186 117.795 133.319 1.00 62.72  ? 663 GLN D O   1 
ATOM   19074 C CB  . GLN D 1 663 ? 157.244 119.328 133.646 1.00 49.05  ? 663 GLN D CB  1 
ATOM   19075 C CG  . GLN D 1 663 ? 156.798 120.759 133.947 1.00 57.74  ? 663 GLN D CG  1 
ATOM   19076 C CD  . GLN D 1 663 ? 155.580 120.819 134.848 1.00 63.94  ? 663 GLN D CD  1 
ATOM   19077 O OE1 . GLN D 1 663 ? 154.929 119.831 135.147 1.00 58.64  ? 663 GLN D OE1 1 
ATOM   19078 N NE2 . GLN D 1 663 ? 155.236 121.988 135.331 1.00 64.63  ? 663 GLN D NE2 1 
ATOM   19079 N N   . LYS D 1 664 ? 158.562 116.925 132.037 1.00 68.27  ? 664 LYS D N   1 
ATOM   19080 C CA  . LYS D 1 664 ? 159.207 115.618 131.862 1.00 55.97  ? 664 LYS D CA  1 
ATOM   19081 C C   . LYS D 1 664 ? 160.492 115.678 131.038 1.00 61.79  ? 664 LYS D C   1 
ATOM   19082 O O   . LYS D 1 664 ? 161.443 115.000 131.394 1.00 72.47  ? 664 LYS D O   1 
ATOM   19083 C CB  . LYS D 1 664 ? 158.231 114.611 131.260 1.00 53.05  ? 664 LYS D CB  1 
ATOM   19084 C CG  . LYS D 1 664 ? 157.062 114.324 132.204 1.00 56.41  ? 664 LYS D CG  1 
ATOM   19085 C CD  . LYS D 1 664 ? 156.513 112.913 132.008 1.00 61.18  ? 664 LYS D CD  1 
ATOM   19086 C CE  . LYS D 1 664 ? 156.003 112.678 130.584 1.00 64.10  ? 664 LYS D CE  1 
ATOM   19087 N NZ  . LYS D 1 664 ? 155.587 111.265 130.394 1.00 69.07  ? 664 LYS D NZ  1 
ATOM   19088 N N   . ALA D 1 665 ? 160.579 116.517 130.007 1.00 48.59  ? 665 ALA D N   1 
ATOM   19089 C CA  . ALA D 1 665 ? 161.816 116.755 129.267 1.00 45.38  ? 665 ALA D CA  1 
ATOM   19090 C C   . ALA D 1 665 ? 162.927 117.345 130.141 1.00 57.27  ? 665 ALA D C   1 
ATOM   19091 O O   . ALA D 1 665 ? 164.031 116.821 130.159 1.00 68.67  ? 665 ALA D O   1 
ATOM   19092 C CB  . ALA D 1 665 ? 161.525 117.664 128.076 1.00 55.42  ? 665 ALA D CB  1 
ATOM   19093 N N   . ILE D 1 666 ? 162.648 118.388 130.920 1.00 66.86  ? 666 ILE D N   1 
ATOM   19094 C CA  . ILE D 1 666 ? 163.614 118.996 131.849 1.00 59.79  ? 666 ILE D CA  1 
ATOM   19095 C C   . ILE D 1 666 ? 164.086 117.976 132.895 1.00 58.29  ? 666 ILE D C   1 
ATOM   19096 O O   . ILE D 1 666 ? 165.275 117.878 133.183 1.00 65.58  ? 666 ILE D O   1 
ATOM   19097 C CB  . ILE D 1 666 ? 162.980 120.241 132.502 1.00 58.52  ? 666 ILE D CB  1 
ATOM   19098 C CG1 . ILE D 1 666 ? 162.778 121.362 131.467 1.00 52.13  ? 666 ILE D CG1 1 
ATOM   19099 C CG2 . ILE D 1 666 ? 163.833 120.769 133.660 1.00 66.01  ? 666 ILE D CG2 1 
ATOM   19100 C CD1 . ILE D 1 666 ? 161.738 122.394 131.892 1.00 58.65  ? 666 ILE D CD1 1 
ATOM   19101 N N   . SER D 1 667 ? 163.162 117.173 133.426 1.00 58.63  ? 667 SER D N   1 
ATOM   19102 C CA  . SER D 1 667 ? 163.443 116.089 134.371 1.00 57.19  ? 667 SER D CA  1 
ATOM   19103 C C   . SER D 1 667 ? 164.370 115.026 133.782 1.00 55.40  ? 667 SER D C   1 
ATOM   19104 O O   . SER D 1 667 ? 165.391 114.698 134.379 1.00 58.75  ? 667 SER D O   1 
ATOM   19105 C CB  . SER D 1 667 ? 162.114 115.477 134.805 1.00 61.39  ? 667 SER D CB  1 
ATOM   19106 O OG  . SER D 1 667 ? 162.323 114.388 135.663 1.00 63.85  ? 667 SER D OG  1 
ATOM   19107 N N   . VAL D 1 668 ? 164.083 114.538 132.572 1.00 65.67  ? 668 VAL D N   1 
ATOM   19108 C CA  . VAL D 1 668 ? 164.920 113.587 131.825 1.00 65.53  ? 668 VAL D CA  1 
ATOM   19109 C C   . VAL D 1 668 ? 166.331 114.110 131.615 1.00 70.24  ? 668 VAL D C   1 
ATOM   19110 O O   . VAL D 1 668 ? 167.291 113.419 131.937 1.00 78.72  ? 668 VAL D O   1 
ATOM   19111 C CB  . VAL D 1 668 ? 164.257 113.274 130.474 1.00 59.88  ? 668 VAL D CB  1 
ATOM   19112 C CG1 . VAL D 1 668 ? 165.190 112.723 129.402 1.00 67.15  ? 668 VAL D CG1 1 
ATOM   19113 C CG2 . VAL D 1 668 ? 163.160 112.244 130.686 1.00 62.97  ? 668 VAL D CG2 1 
ATOM   19114 N N   . LEU D 1 669 ? 166.471 115.322 131.089 1.00 63.77  ? 669 LEU D N   1 
ATOM   19115 C CA  . LEU D 1 669 ? 167.771 115.865 130.715 1.00 60.14  ? 669 LEU D CA  1 
ATOM   19116 C C   . LEU D 1 669 ? 168.659 116.137 131.929 1.00 65.98  ? 669 LEU D C   1 
ATOM   19117 O O   . LEU D 1 669 ? 169.878 116.134 131.800 1.00 75.49  ? 669 LEU D O   1 
ATOM   19118 C CB  . LEU D 1 669 ? 167.543 117.128 129.880 1.00 65.80  ? 669 LEU D CB  1 
ATOM   19119 C CG  . LEU D 1 669 ? 166.816 116.858 128.555 1.00 66.00  ? 669 LEU D CG  1 
ATOM   19120 C CD1 . LEU D 1 669 ? 166.266 118.161 128.004 1.00 66.40  ? 669 LEU D CD1 1 
ATOM   19121 C CD2 . LEU D 1 669 ? 167.747 116.238 127.529 1.00 63.71  ? 669 LEU D CD2 1 
ATOM   19122 N N   . GLU D 1 670 ? 168.079 116.326 133.110 1.00 79.19  ? 670 GLU D N   1 
ATOM   19123 C CA  . GLU D 1 670 ? 168.792 116.311 134.384 1.00 77.84  ? 670 GLU D CA  1 
ATOM   19124 C C   . GLU D 1 670 ? 169.163 114.900 134.859 1.00 77.81  ? 670 GLU D C   1 
ATOM   19125 O O   . GLU D 1 670 ? 170.328 114.659 135.175 1.00 77.90  ? 670 GLU D O   1 
ATOM   19126 C CB  . GLU D 1 670 ? 167.949 117.037 135.438 1.00 73.17  ? 670 GLU D CB  1 
ATOM   19127 C CG  . GLU D 1 670 ? 168.120 118.552 135.329 1.00 79.06  ? 670 GLU D CG  1 
ATOM   19128 C CD  . GLU D 1 670 ? 169.578 118.954 135.575 1.00 89.64  ? 670 GLU D CD  1 
ATOM   19129 O OE1 . GLU D 1 670 ? 170.155 118.512 136.591 1.00 89.29  ? 670 GLU D OE1 1 
ATOM   19130 O OE2 . GLU D 1 670 ? 170.185 119.665 134.739 1.00 93.46  ? 670 GLU D OE2 1 
ATOM   19131 N N   . MET D 1 671 ? 168.226 113.951 134.854 1.00 70.39  ? 671 MET D N   1 
ATOM   19132 C CA  . MET D 1 671 ? 168.484 112.564 135.252 1.00 69.45  ? 671 MET D CA  1 
ATOM   19133 C C   . MET D 1 671 ? 169.542 111.851 134.413 1.00 67.77  ? 671 MET D C   1 
ATOM   19134 O O   . MET D 1 671 ? 170.272 111.016 134.939 1.00 79.28  ? 671 MET D O   1 
ATOM   19135 C CB  . MET D 1 671 ? 167.197 111.748 135.163 1.00 67.53  ? 671 MET D CB  1 
ATOM   19136 C CG  . MET D 1 671 ? 166.234 112.051 136.300 1.00 64.09  ? 671 MET D CG  1 
ATOM   19137 S SD  . MET D 1 671 ? 164.897 110.857 136.397 1.00 67.34  ? 671 MET D SD  1 
ATOM   19138 C CE  . MET D 1 671 ? 163.951 111.246 134.914 1.00 70.66  ? 671 MET D CE  1 
ATOM   19139 N N   . GLU D 1 672 ? 169.675 112.161 133.127 1.00 73.88  ? 672 GLU D N   1 
ATOM   19140 C CA  . GLU D 1 672 ? 170.694 111.560 132.260 1.00 76.45  ? 672 GLU D CA  1 
ATOM   19141 C C   . GLU D 1 672 ? 172.141 111.823 132.702 1.00 80.94  ? 672 GLU D C   1 
ATOM   19142 O O   . GLU D 1 672 ? 173.028 111.064 132.329 1.00 77.09  ? 672 GLU D O   1 
ATOM   19143 C CB  . GLU D 1 672 ? 170.521 112.084 130.834 1.00 75.01  ? 672 GLU D CB  1 
ATOM   19144 C CG  . GLU D 1 672 ? 169.412 111.360 130.070 1.00 77.20  ? 672 GLU D CG  1 
ATOM   19145 C CD  . GLU D 1 672 ? 169.453 111.768 128.597 1.00 85.84  ? 672 GLU D CD  1 
ATOM   19146 O OE1 . GLU D 1 672 ? 169.638 112.966 128.307 1.00 85.17  ? 672 GLU D OE1 1 
ATOM   19147 O OE2 . GLU D 1 672 ? 169.347 110.898 127.708 1.00 85.99  ? 672 GLU D OE2 1 
ATOM   19148 N N   . ASN D 1 673 ? 172.403 112.862 133.501 1.00 88.96  ? 673 ASN D N   1 
ATOM   19149 C CA  . ASN D 1 673 ? 173.734 113.135 134.056 1.00 86.04  ? 673 ASN D CA  1 
ATOM   19150 C C   . ASN D 1 673 ? 174.044 112.296 135.302 1.00 85.70  ? 673 ASN D C   1 
ATOM   19151 O O   . ASN D 1 673 ? 175.161 112.337 135.805 1.00 91.09  ? 673 ASN D O   1 
ATOM   19152 C CB  . ASN D 1 673 ? 173.882 114.628 134.378 1.00 88.08  ? 673 ASN D CB  1 
ATOM   19153 C CG  . ASN D 1 673 ? 173.405 115.516 133.257 1.00 86.53  ? 673 ASN D CG  1 
ATOM   19154 O OD1 . ASN D 1 673 ? 174.064 115.713 132.248 1.00 85.00  ? 673 ASN D OD1 1 
ATOM   19155 N ND2 . ASN D 1 673 ? 172.213 116.032 133.394 1.00 83.18  ? 673 ASN D ND2 1 
ATOM   19156 N N   . GLY D 1 674 ? 173.080 111.547 135.832 1.00 84.65  ? 674 GLY D N   1 
ATOM   19157 C CA  . GLY D 1 674 ? 173.210 110.876 137.117 1.00 83.46  ? 674 GLY D CA  1 
ATOM   19158 C C   . GLY D 1 674 ? 173.159 111.877 138.266 1.00 86.28  ? 674 GLY D C   1 
ATOM   19159 O O   . GLY D 1 674 ? 172.297 112.750 138.305 1.00 90.01  ? 674 GLY D O   1 
ATOM   19160 N N   . TYR D 1 675 ? 174.087 111.747 139.204 1.00 87.36  ? 675 TYR D N   1 
ATOM   19161 C CA  . TYR D 1 675 ? 174.157 112.548 140.424 1.00 88.28  ? 675 TYR D CA  1 
ATOM   19162 C C   . TYR D 1 675 ? 175.504 113.266 140.529 1.00 89.58  ? 675 TYR D C   1 
ATOM   19163 O O   . TYR D 1 675 ? 176.488 112.826 139.943 1.00 92.01  ? 675 TYR D O   1 
ATOM   19164 C CB  . TYR D 1 675 ? 173.941 111.645 141.640 1.00 86.22  ? 675 TYR D CB  1 
ATOM   19165 C CG  . TYR D 1 675 ? 172.702 110.767 141.638 1.00 88.03  ? 675 TYR D CG  1 
ATOM   19166 C CD1 . TYR D 1 675 ? 171.420 111.341 141.740 1.00 83.48  ? 675 TYR D CD1 1 
ATOM   19167 C CD2 . TYR D 1 675 ? 172.839 109.370 141.600 1.00 87.74  ? 675 TYR D CD2 1 
ATOM   19168 C CE1 . TYR D 1 675 ? 170.280 110.519 141.799 1.00 84.75  ? 675 TYR D CE1 1 
ATOM   19169 C CE2 . TYR D 1 675 ? 171.704 108.546 141.661 1.00 84.83  ? 675 TYR D CE2 1 
ATOM   19170 C CZ  . TYR D 1 675 ? 170.422 109.117 141.759 1.00 86.33  ? 675 TYR D CZ  1 
ATOM   19171 O OH  . TYR D 1 675 ? 169.340 108.301 141.817 1.00 86.61  ? 675 TYR D OH  1 
ATOM   19172 N N   . TRP D 1 676 ? 175.587 114.334 141.321 1.00 87.26  ? 676 TRP D N   1 
ATOM   19173 C CA  . TRP D 1 676 ? 176.807 115.142 141.479 1.00 84.73  ? 676 TRP D CA  1 
ATOM   19174 C C   . TRP D 1 676 ? 178.055 114.323 141.866 1.00 87.96  ? 676 TRP D C   1 
ATOM   19175 O O   . TRP D 1 676 ? 179.168 114.676 141.474 1.00 92.78  ? 676 TRP D O   1 
ATOM   19176 C CB  . TRP D 1 676 ? 176.520 116.241 142.512 1.00 84.47  ? 676 TRP D CB  1 
ATOM   19177 C CG  . TRP D 1 676 ? 176.255 115.783 143.916 1.00 90.74  ? 676 TRP D CG  1 
ATOM   19178 C CD1 . TRP D 1 676 ? 175.041 115.520 144.451 1.00 87.43  ? 676 TRP D CD1 1 
ATOM   19179 C CD2 . TRP D 1 676 ? 177.219 115.501 144.975 1.00 88.67  ? 676 TRP D CD2 1 
ATOM   19180 N NE1 . TRP D 1 676 ? 175.193 115.089 145.751 1.00 85.19  ? 676 TRP D NE1 1 
ATOM   19181 C CE2 . TRP D 1 676 ? 176.515 115.039 146.119 1.00 86.51  ? 676 TRP D CE2 1 
ATOM   19182 C CE3 . TRP D 1 676 ? 178.625 115.583 145.080 1.00 84.71  ? 676 TRP D CE3 1 
ATOM   19183 C CZ2 . TRP D 1 676 ? 177.166 114.651 147.296 1.00 85.81  ? 676 TRP D CZ2 1 
ATOM   19184 C CZ3 . TRP D 1 676 ? 179.290 115.197 146.257 1.00 87.19  ? 676 TRP D CZ3 1 
ATOM   19185 C CH2 . TRP D 1 676 ? 178.565 114.723 147.360 1.00 87.66  ? 676 TRP D CH2 1 
ATOM   19186 N N   . TRP D 1 677 ? 177.865 113.213 142.586 1.00 88.94  ? 677 TRP D N   1 
ATOM   19187 C CA  . TRP D 1 677 ? 178.878 112.255 143.050 1.00 90.93  ? 677 TRP D CA  1 
ATOM   19188 C C   . TRP D 1 677 ? 179.096 111.045 142.121 1.00 94.40  ? 677 TRP D C   1 
ATOM   19189 O O   . TRP D 1 677 ? 180.067 110.308 142.296 1.00 96.28  ? 677 TRP D O   1 
ATOM   19190 C CB  . TRP D 1 677 ? 178.430 111.765 144.434 1.00 88.68  ? 677 TRP D CB  1 
ATOM   19191 C CG  . TRP D 1 677 ? 177.119 111.034 144.467 1.00 85.07  ? 677 TRP D CG  1 
ATOM   19192 C CD1 . TRP D 1 677 ? 175.905 111.616 144.564 1.00 88.46  ? 677 TRP D CD1 1 
ATOM   19193 C CD2 . TRP D 1 677 ? 176.853 109.599 144.399 1.00 87.41  ? 677 TRP D CD2 1 
ATOM   19194 N NE1 . TRP D 1 677 ? 174.919 110.657 144.528 1.00 89.12  ? 677 TRP D NE1 1 
ATOM   19195 C CE2 . TRP D 1 677 ? 175.441 109.396 144.402 1.00 89.10  ? 677 TRP D CE2 1 
ATOM   19196 C CE3 . TRP D 1 677 ? 177.659 108.445 144.345 1.00 89.28  ? 677 TRP D CE3 1 
ATOM   19197 C CZ2 . TRP D 1 677 ? 174.856 108.128 144.304 1.00 88.06  ? 677 TRP D CZ2 1 
ATOM   19198 C CZ3 . TRP D 1 677 ? 177.084 107.162 144.249 1.00 92.34  ? 677 TRP D CZ3 1 
ATOM   19199 C CH2 . TRP D 1 677 ? 175.690 107.005 144.214 1.00 90.62  ? 677 TRP D CH2 1 
ATOM   19200 N N   . CYS D 1 678 ? 178.212 110.807 141.151 1.00 96.73  ? 678 CYS D N   1 
ATOM   19201 C CA  . CYS D 1 678 ? 178.204 109.634 140.269 1.00 96.26  ? 678 CYS D CA  1 
ATOM   19202 C C   . CYS D 1 678 ? 177.631 110.035 138.906 1.00 98.92  ? 678 CYS D C   1 
ATOM   19203 O O   . CYS D 1 678 ? 176.437 109.894 138.625 1.00 100.42 ? 678 CYS D O   1 
ATOM   19204 C CB  . CYS D 1 678 ? 177.426 108.492 140.931 1.00 99.90  ? 678 CYS D CB  1 
ATOM   19205 S SG  . CYS D 1 678 ? 177.361 107.032 139.851 1.00 101.59 ? 678 CYS D SG  1 
ATOM   19206 N N   . ARG D 1 679 ? 178.502 110.636 138.093 1.00 102.44 ? 679 ARG D N   1 
ATOM   19207 C CA  . ARG D 1 679 ? 178.154 111.292 136.828 1.00 99.87  ? 679 ARG D CA  1 
ATOM   19208 C C   . ARG D 1 679 ? 178.046 110.237 135.729 1.00 99.70  ? 679 ARG D C   1 
ATOM   19209 O O   . ARG D 1 679 ? 179.048 109.682 135.291 1.00 100.11 ? 679 ARG D O   1 
ATOM   19210 C CB  . ARG D 1 679 ? 179.163 112.419 136.536 1.00 98.28  ? 679 ARG D CB  1 
ATOM   19211 C CG  . ARG D 1 679 ? 179.111 113.477 137.657 1.00 99.48  ? 679 ARG D CG  1 
ATOM   19212 C CD  . ARG D 1 679 ? 180.190 114.555 137.551 1.00 101.77 ? 679 ARG D CD  1 
ATOM   19213 N NE  . ARG D 1 679 ? 180.318 115.273 138.835 1.00 106.47 ? 679 ARG D NE  1 
ATOM   19214 C CZ  . ARG D 1 679 ? 181.084 116.305 139.123 1.00 104.43 ? 679 ARG D CZ  1 
ATOM   19215 N NH1 . ARG D 1 679 ? 181.103 116.762 140.336 1.00 100.65 ? 679 ARG D NH1 1 
ATOM   19216 N NH2 . ARG D 1 679 ? 181.835 116.887 138.237 1.00 100.91 ? 679 ARG D NH2 1 
ATOM   19217 N N   . ARG D 1 680 ? 176.813 109.920 135.339 1.00 100.63 ? 680 ARG D N   1 
ATOM   19218 C CA  . ARG D 1 680 ? 176.415 108.800 134.469 1.00 96.87  ? 680 ARG D CA  1 
ATOM   19219 C C   . ARG D 1 680 ? 176.985 108.926 133.053 1.00 101.71 ? 680 ARG D C   1 
ATOM   19220 O O   . ARG D 1 680 ? 176.944 109.996 132.458 1.00 100.59 ? 680 ARG D O   1 
ATOM   19221 C CB  . ARG D 1 680 ? 174.876 108.761 134.488 1.00 98.04  ? 680 ARG D CB  1 
ATOM   19222 C CG  . ARG D 1 680 ? 174.180 107.817 133.507 1.00 98.38  ? 680 ARG D CG  1 
ATOM   19223 C CD  . ARG D 1 680 ? 172.663 107.869 133.752 1.00 102.05 ? 680 ARG D CD  1 
ATOM   19224 N NE  . ARG D 1 680 ? 171.893 107.419 132.574 1.00 102.50 ? 680 ARG D NE  1 
ATOM   19225 C CZ  . ARG D 1 680 ? 171.053 106.406 132.491 1.00 105.34 ? 680 ARG D CZ  1 
ATOM   19226 N NH1 . ARG D 1 680 ? 170.405 106.178 131.387 1.00 101.87 ? 680 ARG D NH1 1 
ATOM   19227 N NH2 . ARG D 1 680 ? 170.842 105.591 133.481 1.00 103.84 ? 680 ARG D NH2 1 
ATOM   19228 N N   . LYS D 1 681 ? 177.467 107.822 132.490 1.00 111.64 ? 681 LYS D N   1 
ATOM   19229 C CA  . LYS D 1 681 ? 177.853 107.736 131.080 1.00 109.83 ? 681 LYS D CA  1 
ATOM   19230 C C   . LYS D 1 681 ? 176.610 107.679 130.188 1.00 110.00 ? 681 LYS D C   1 
ATOM   19231 O O   . LYS D 1 681 ? 175.791 106.769 130.328 1.00 108.52 ? 681 LYS D O   1 
ATOM   19232 C CB  . LYS D 1 681 ? 178.712 106.492 130.877 1.00 104.08 ? 681 LYS D CB  1 
ATOM   19233 N N   . LYS D 1 682 ? 176.438 108.651 129.284 1.00 95.89  ? 682 LYS D N   1 
ATOM   19234 C CA  . LYS D 1 682 ? 175.230 108.775 128.452 1.00 97.99  ? 682 LYS D CA  1 
ATOM   19235 C C   . LYS D 1 682 ? 175.160 107.715 127.349 1.00 102.44 ? 682 LYS D C   1 
ATOM   19236 O O   . LYS D 1 682 ? 176.063 107.592 126.525 1.00 98.18  ? 682 LYS D O   1 
ATOM   19237 C CB  . LYS D 1 682 ? 175.125 110.187 127.855 1.00 97.43  ? 682 LYS D CB  1 
ATOM   19238 C CG  . LYS D 1 682 ? 174.788 111.241 128.918 1.00 99.21  ? 682 LYS D CG  1 
ATOM   19239 C CD  . LYS D 1 682 ? 174.644 112.612 128.258 1.00 99.55  ? 682 LYS D CD  1 
ATOM   19240 C CE  . LYS D 1 682 ? 174.264 113.686 129.274 1.00 97.65  ? 682 LYS D CE  1 
ATOM   19241 N NZ  . LYS D 1 682 ? 174.249 115.029 128.641 1.00 98.54  ? 682 LYS D NZ  1 
ATOM   19242 N N   . HIS D 1 683 ? 174.044 106.991 127.310 1.00 103.16 ? 683 HIS D N   1 
ATOM   19243 C CA  . HIS D 1 683 ? 173.625 106.122 126.204 1.00 99.60  ? 683 HIS D CA  1 
ATOM   19244 C C   . HIS D 1 683 ? 173.186 106.961 124.992 1.00 98.73  ? 683 HIS D C   1 
ATOM   19245 O O   . HIS D 1 683 ? 172.644 108.053 125.161 1.00 99.98  ? 683 HIS D O   1 
ATOM   19246 C CB  . HIS D 1 683 ? 172.510 105.203 126.735 1.00 99.52  ? 683 HIS D CB  1 
ATOM   19247 C CG  . HIS D 1 683 ? 171.789 104.394 125.690 1.00 106.44 ? 683 HIS D CG  1 
ATOM   19248 N ND1 . HIS D 1 683 ? 170.542 104.710 125.155 1.00 102.00 ? 683 HIS D ND1 1 
ATOM   19249 C CD2 . HIS D 1 683 ? 172.239 103.250 125.111 1.00 104.29 ? 683 HIS D CD2 1 
ATOM   19250 C CE1 . HIS D 1 683 ? 170.263 103.748 124.265 1.00 100.82 ? 683 HIS D CE1 1 
ATOM   19251 N NE2 . HIS D 1 683 ? 171.266 102.856 124.220 1.00 101.58 ? 683 HIS D NE2 1 
ATOM   19252 N N   . ARG D 1 684 ? 173.441 106.474 123.771 1.00 88.21  ? 684 ARG D N   1 
ATOM   19253 C CA  . ARG D 1 684 ? 173.151 107.166 122.505 1.00 86.65  ? 684 ARG D CA  1 
ATOM   19254 C C   . ARG D 1 684 ? 171.906 106.586 121.842 1.00 88.38  ? 684 ARG D C   1 
ATOM   19255 O O   . ARG D 1 684 ? 171.807 105.373 121.670 1.00 88.88  ? 684 ARG D O   1 
ATOM   19256 C CB  . ARG D 1 684 ? 174.382 107.072 121.596 1.00 86.07  ? 684 ARG D CB  1 
ATOM   19257 C CG  . ARG D 1 684 ? 174.298 108.034 120.412 1.00 81.98  ? 684 ARG D CG  1 
ATOM   19258 C CD  . ARG D 1 684 ? 175.608 108.021 119.628 1.00 81.18  ? 684 ARG D CD  1 
ATOM   19259 N NE  . ARG D 1 684 ? 175.640 109.100 118.631 1.00 88.79  ? 684 ARG D NE  1 
ATOM   19260 C CZ  . ARG D 1 684 ? 176.654 109.431 117.859 1.00 91.31  ? 684 ARG D CZ  1 
ATOM   19261 N NH1 . ARG D 1 684 ? 176.567 110.449 117.058 1.00 87.79  ? 684 ARG D NH1 1 
ATOM   19262 N NH2 . ARG D 1 684 ? 177.771 108.765 117.864 1.00 90.97  ? 684 ARG D NH2 1 
ATOM   19263 N N   . GLU D 1 685 ? 170.942 107.429 121.505 1.00 88.14  ? 685 GLU D N   1 
ATOM   19264 C CA  . GLU D 1 685 ? 169.634 107.006 120.994 1.00 88.68  ? 685 GLU D CA  1 
ATOM   19265 C C   . GLU D 1 685 ? 169.661 106.707 119.485 1.00 89.96  ? 685 GLU D C   1 
ATOM   19266 O O   . GLU D 1 685 ? 170.476 107.245 118.738 1.00 93.14  ? 685 GLU D O   1 
ATOM   19267 C CB  . GLU D 1 685 ? 168.569 108.069 121.288 1.00 88.72  ? 685 GLU D CB  1 
ATOM   19268 C CG  . GLU D 1 685 ? 168.539 108.602 122.728 1.00 89.74  ? 685 GLU D CG  1 
ATOM   19269 C CD  . GLU D 1 685 ? 168.061 107.627 123.805 1.00 91.04  ? 685 GLU D CD  1 
ATOM   19270 O OE1 . GLU D 1 685 ? 167.514 106.555 123.481 1.00 94.70  ? 685 GLU D OE1 1 
ATOM   19271 O OE2 . GLU D 1 685 ? 168.203 107.993 124.990 1.00 93.44  ? 685 GLU D OE2 1 
ATOM   19272 N N   . GLY D 1 686 ? 168.738 105.876 119.008 1.00 80.42  ? 686 GLY D N   1 
ATOM   19273 C CA  . GLY D 1 686 ? 168.694 105.463 117.607 1.00 80.34  ? 686 GLY D CA  1 
ATOM   19274 C C   . GLY D 1 686 ? 169.779 104.454 117.226 1.00 82.16  ? 686 GLY D C   1 
ATOM   19275 O O   . GLY D 1 686 ? 170.437 103.866 118.082 1.00 81.79  ? 686 GLY D O   1 
ATOM   19276 N N   . ARG D 1 687 ? 169.944 104.223 115.924 1.00 93.46  ? 687 ARG D N   1 
ATOM   19277 C CA  . ARG D 1 687 ? 170.893 103.279 115.318 1.00 91.04  ? 687 ARG D CA  1 
ATOM   19278 C C   . ARG D 1 687 ? 171.688 103.967 114.222 1.00 89.37  ? 687 ARG D C   1 
ATOM   19279 O O   . ARG D 1 687 ? 171.138 104.787 113.497 1.00 91.72  ? 687 ARG D O   1 
ATOM   19280 C CB  . ARG D 1 687 ? 170.149 102.081 114.710 1.00 93.14  ? 687 ARG D CB  1 
ATOM   19281 C CG  . ARG D 1 687 ? 169.380 101.235 115.723 1.00 96.82  ? 687 ARG D CG  1 
ATOM   19282 C CD  . ARG D 1 687 ? 168.780 100.009 115.036 1.00 95.84  ? 687 ARG D CD  1 
ATOM   19283 N NE  . ARG D 1 687 ? 167.964 99.206  115.961 1.00 101.36 ? 687 ARG D NE  1 
ATOM   19284 C CZ  . ARG D 1 687 ? 167.546 97.968  115.776 1.00 100.53 ? 687 ARG D CZ  1 
ATOM   19285 N NH1 . ARG D 1 687 ? 166.832 97.369  116.680 1.00 93.59  ? 687 ARG D NH1 1 
ATOM   19286 N NH2 . ARG D 1 687 ? 167.818 97.303  114.696 1.00 97.20  ? 687 ARG D NH2 1 
ATOM   19287 N N   . LEU D 1 688 ? 172.948 103.597 114.041 1.00 84.03  ? 688 LEU D N   1 
ATOM   19288 C CA  . LEU D 1 688 ? 173.731 104.023 112.882 1.00 88.31  ? 688 LEU D CA  1 
ATOM   19289 C C   . LEU D 1 688 ? 173.248 103.289 111.623 1.00 90.97  ? 688 LEU D C   1 
ATOM   19290 O O   . LEU D 1 688 ? 173.501 102.097 111.473 1.00 95.43  ? 688 LEU D O   1 
ATOM   19291 C CB  . LEU D 1 688 ? 175.220 103.788 113.175 1.00 92.33  ? 688 LEU D CB  1 
ATOM   19292 C CG  . LEU D 1 688 ? 176.175 104.197 112.045 1.00 93.29  ? 688 LEU D CG  1 
ATOM   19293 C CD1 . LEU D 1 688 ? 176.038 105.663 111.670 1.00 93.90  ? 688 LEU D CD1 1 
ATOM   19294 C CD2 . LEU D 1 688 ? 177.612 103.962 112.484 1.00 93.30  ? 688 LEU D CD2 1 
ATOM   19295 N N   . LEU D 1 689 ? 172.558 103.986 110.724 1.00 96.65  ? 689 LEU D N   1 
ATOM   19296 C CA  . LEU D 1 689 ? 171.953 103.419 109.518 1.00 97.36  ? 689 LEU D CA  1 
ATOM   19297 C C   . LEU D 1 689 ? 172.407 104.165 108.265 1.00 98.52  ? 689 LEU D C   1 
ATOM   19298 O O   . LEU D 1 689 ? 172.496 105.392 108.262 1.00 102.84 ? 689 LEU D O   1 
ATOM   19299 C CB  . LEU D 1 689 ? 170.418 103.455 109.635 1.00 96.65  ? 689 LEU D CB  1 
ATOM   19300 C CG  . LEU D 1 689 ? 169.824 102.598 110.763 1.00 100.75 ? 689 LEU D CG  1 
ATOM   19301 C CD1 . LEU D 1 689 ? 168.319 102.799 110.833 1.00 95.11  ? 689 LEU D CD1 1 
ATOM   19302 C CD2 . LEU D 1 689 ? 170.076 101.109 110.558 1.00 99.22  ? 689 LEU D CD2 1 
ATOM   19303 N N   . LYS D 1 690 ? 172.654 103.427 107.178 1.00 107.96 ? 690 LYS D N   1 
ATOM   19304 C CA  . LYS D 1 690 ? 172.846 103.991 105.834 1.00 111.69 ? 690 LYS D CA  1 
ATOM   19305 C C   . LYS D 1 690 ? 171.503 104.467 105.280 1.00 109.89 ? 690 LYS D C   1 
ATOM   19306 O O   . LYS D 1 690 ? 170.614 103.654 105.036 1.00 107.45 ? 690 LYS D O   1 
ATOM   19307 C CB  . LYS D 1 690 ? 173.504 102.943 104.920 1.00 109.95 ? 690 LYS D CB  1 
ATOM   19308 C CG  . LYS D 1 690 ? 173.764 103.487 103.509 1.00 109.58 ? 690 LYS D CG  1 
ATOM   19309 C CD  . LYS D 1 690 ? 174.483 102.451 102.643 1.00 108.92 ? 690 LYS D CD  1 
ATOM   19310 C CE  . LYS D 1 690 ? 174.523 102.910 101.188 1.00 109.69 ? 690 LYS D CE  1 
ATOM   19311 N NZ  . LYS D 1 690 ? 175.206 101.933 100.316 1.00 108.72 ? 690 LYS D NZ  1 
ATOM   19312 N N   . VAL D 1 691 ? 171.363 105.770 105.064 1.00 101.04 ? 691 VAL D N   1 
ATOM   19313 C CA  . VAL D 1 691 ? 170.159 106.381 104.463 1.00 102.30 ? 691 VAL D CA  1 
ATOM   19314 C C   . VAL D 1 691 ? 170.316 106.658 102.962 1.00 104.14 ? 691 VAL D C   1 
ATOM   19315 O O   . VAL D 1 691 ? 169.320 106.828 102.261 1.00 100.50 ? 691 VAL D O   1 
ATOM   19316 C CB  . VAL D 1 691 ? 169.727 107.640 105.237 1.00 97.93  ? 691 VAL D CB  1 
ATOM   19317 C CG1 . VAL D 1 691 ? 169.231 107.272 106.633 1.00 93.64  ? 691 VAL D CG1 1 
ATOM   19318 C CG2 . VAL D 1 691 ? 170.827 108.684 105.374 1.00 97.34  ? 691 VAL D CG2 1 
ATOM   19319 N N   . GLY D 1 692 ? 171.548 106.659 102.448 1.00 116.75 ? 692 GLY D N   1 
ATOM   19320 C CA  . GLY D 1 692 ? 171.858 106.908 101.040 1.00 115.94 ? 692 GLY D CA  1 
ATOM   19321 C C   . GLY D 1 692 ? 173.361 107.038 100.773 1.00 120.33 ? 692 GLY D C   1 
ATOM   19322 O O   . GLY D 1 692 ? 174.183 106.500 101.519 1.00 120.43 ? 692 GLY D O   1 
ATOM   19323 N N   . THR D 1 693 ? 173.728 107.766 99.713  1.00 132.06 ? 693 THR D N   1 
ATOM   19324 C CA  . THR D 1 693 ? 175.124 108.075 99.335  1.00 132.63 ? 693 THR D CA  1 
ATOM   19325 C C   . THR D 1 693 ? 175.433 109.563 99.553  1.00 130.69 ? 693 THR D C   1 
ATOM   19326 O O   . THR D 1 693 ? 174.675 110.428 99.112  1.00 129.54 ? 693 THR D O   1 
ATOM   19327 C CB  . THR D 1 693 ? 175.406 107.654 97.883  1.00 130.11 ? 693 THR D CB  1 
ATOM   19328 O OG1 . THR D 1 693 ? 175.097 106.287 97.721  1.00 128.04 ? 693 THR D OG1 1 
ATOM   19329 C CG2 . THR D 1 693 ? 176.872 107.821 97.492  1.00 127.99 ? 693 THR D CG2 1 
ATOM   19330 N N   . ARG D 1 694 ? 176.532 109.880 100.254 1.00 133.79 ? 694 ARG D N   1 
ATOM   19331 C CA  . ARG D 1 694 ? 176.871 111.242 100.708 1.00 133.33 ? 694 ARG D CA  1 
ATOM   19332 C C   . ARG D 1 694 ? 177.404 112.125 99.571  1.00 132.70 ? 694 ARG D C   1 
ATOM   19333 O O   . ARG D 1 694 ? 178.460 111.841 99.005  1.00 131.37 ? 694 ARG D O   1 
ATOM   19334 C CB  . ARG D 1 694 ? 177.840 111.151 101.902 1.00 132.78 ? 694 ARG D CB  1 
ATOM   19335 C CG  . ARG D 1 694 ? 177.842 112.445 102.728 1.00 132.47 ? 694 ARG D CG  1 
ATOM   19336 C CD  . ARG D 1 694 ? 178.772 112.304 103.939 1.00 132.41 ? 694 ARG D CD  1 
ATOM   19337 N NE  . ARG D 1 694 ? 178.618 113.426 104.884 1.00 135.36 ? 694 ARG D NE  1 
ATOM   19338 C CZ  . ARG D 1 694 ? 179.348 113.660 105.960 1.00 135.14 ? 694 ARG D CZ  1 
ATOM   19339 N NH1 . ARG D 1 694 ? 179.052 114.634 106.767 1.00 132.21 ? 694 ARG D NH1 1 
ATOM   19340 N NH2 . ARG D 1 694 ? 180.386 112.936 106.263 1.00 135.32 ? 694 ARG D NH2 1 
ATOM   19341 N N   . PRO D 1 699 ? 179.505 106.149 102.665 1.00 127.01 ? 699 PRO D N   1 
ATOM   19342 C CA  . PRO D 1 699 ? 178.124 106.496 102.366 1.00 128.10 ? 699 PRO D CA  1 
ATOM   19343 C C   . PRO D 1 699 ? 177.518 107.525 103.331 1.00 129.27 ? 699 PRO D C   1 
ATOM   19344 O O   . PRO D 1 699 ? 178.186 108.058 104.216 1.00 125.77 ? 699 PRO D O   1 
ATOM   19345 C CB  . PRO D 1 699 ? 177.366 105.167 102.381 1.00 125.10 ? 699 PRO D CB  1 
ATOM   19346 C CG  . PRO D 1 699 ? 178.435 104.142 102.036 1.00 125.90 ? 699 PRO D CG  1 
ATOM   19347 C CD  . PRO D 1 699 ? 179.681 104.716 102.695 1.00 125.87 ? 699 PRO D CD  1 
ATOM   19348 N N   . ASP D 1 700 ? 176.231 107.829 103.154 1.00 121.72 ? 700 ASP D N   1 
ATOM   19349 C CA  . ASP D 1 700 ? 175.472 108.678 104.072 1.00 120.33 ? 700 ASP D CA  1 
ATOM   19350 C C   . ASP D 1 700 ? 174.937 107.816 105.220 1.00 115.88 ? 700 ASP D C   1 
ATOM   19351 O O   . ASP D 1 700 ? 173.838 107.268 105.154 1.00 111.97 ? 700 ASP D O   1 
ATOM   19352 C CB  . ASP D 1 700 ? 174.370 109.419 103.297 1.00 119.14 ? 700 ASP D CB  1 
ATOM   19353 C CG  . ASP D 1 700 ? 173.746 110.583 104.067 1.00 121.12 ? 700 ASP D CG  1 
ATOM   19354 O OD1 . ASP D 1 700 ? 174.155 110.875 105.209 1.00 119.32 ? 700 ASP D OD1 1 
ATOM   19355 O OD2 . ASP D 1 700 ? 172.845 111.248 103.513 1.00 119.03 ? 700 ASP D OD2 1 
ATOM   19356 N N   . GLU D 1 701 ? 175.763 107.623 106.248 1.00 106.86 ? 701 GLU D N   1 
ATOM   19357 C CA  . GLU D 1 701 ? 175.444 106.832 107.436 1.00 108.21 ? 701 GLU D CA  1 
ATOM   19358 C C   . GLU D 1 701 ? 175.222 107.760 108.630 1.00 108.03 ? 701 GLU D C   1 
ATOM   19359 O O   . GLU D 1 701 ? 176.078 108.588 108.951 1.00 107.92 ? 701 GLU D O   1 
ATOM   19360 C CB  . GLU D 1 701 ? 176.550 105.807 107.731 1.00 109.74 ? 701 GLU D CB  1 
ATOM   19361 C CG  . GLU D 1 701 ? 176.701 104.783 106.599 1.00 112.17 ? 701 GLU D CG  1 
ATOM   19362 C CD  . GLU D 1 701 ? 177.767 103.713 106.883 1.00 112.78 ? 701 GLU D CD  1 
ATOM   19363 O OE1 . GLU D 1 701 ? 178.815 104.024 107.492 1.00 111.07 ? 701 GLU D OE1 1 
ATOM   19364 O OE2 . GLU D 1 701 ? 177.570 102.547 106.476 1.00 110.37 ? 701 GLU D OE2 1 
ATOM   19365 N N   . ARG D 1 702 ? 174.035 107.626 109.257 1.00 90.58  ? 702 ARG D N   1 
ATOM   19366 C CA  . ARG D 1 702 ? 173.623 108.565 110.339 1.00 85.40  ? 702 ARG D CA  1 
ATOM   19367 C C   . ARG D 1 702 ? 172.913 107.891 111.500 1.00 88.29  ? 702 ARG D C   1 
ATOM   19368 O O   . ARG D 1 702 ? 172.218 106.880 111.273 1.00 93.38  ? 702 ARG D O   1 
ATOM   19369 C CB  . ARG D 1 702 ? 172.565 109.517 109.778 1.00 82.94  ? 702 ARG D CB  1 
ATOM   19370 C CG  . ARG D 1 702 ? 172.990 110.247 108.510 1.00 83.69  ? 702 ARG D CG  1 
ATOM   19371 C CD  . ARG D 1 702 ? 171.992 111.362 108.249 1.00 87.72  ? 702 ARG D CD  1 
ATOM   19372 N NE  . ARG D 1 702 ? 172.168 111.909 106.910 1.00 89.74  ? 702 ARG D NE  1 
ATOM   19373 C CZ  . ARG D 1 702 ? 171.375 112.823 106.361 1.00 88.69  ? 702 ARG D CZ  1 
ATOM   19374 N NH1 . ARG D 1 702 ? 171.615 113.256 105.136 1.00 85.82  ? 702 ARG D NH1 1 
ATOM   19375 N NH2 . ARG D 1 702 ? 170.345 113.298 107.038 1.00 88.56  ? 702 ARG D NH2 1 
ATOM   19376 N N   . TRP D 1 703 ? 173.088 108.444 112.696 1.00 86.67  ? 703 TRP D N   1 
ATOM   19377 C CA  . TRP D 1 703 ? 172.329 107.998 113.858 1.00 87.08  ? 703 TRP D CA  1 
ATOM   19378 C C   . TRP D 1 703 ? 170.867 108.401 113.702 1.00 85.76  ? 703 TRP D C   1 
ATOM   19379 O O   . TRP D 1 703 ? 170.464 109.517 114.014 1.00 88.00  ? 703 TRP D O   1 
ATOM   19380 C CB  . TRP D 1 703 ? 172.996 108.504 115.130 1.00 81.52  ? 703 TRP D CB  1 
ATOM   19381 C CG  . TRP D 1 703 ? 174.230 107.720 115.432 1.00 83.41  ? 703 TRP D CG  1 
ATOM   19382 C CD1 . TRP D 1 703 ? 175.433 107.886 114.844 1.00 85.01  ? 703 TRP D CD1 1 
ATOM   19383 C CD2 . TRP D 1 703 ? 174.363 106.550 116.290 1.00 87.89  ? 703 TRP D CD2 1 
ATOM   19384 N NE1 . TRP D 1 703 ? 176.299 106.910 115.286 1.00 86.51  ? 703 TRP D NE1 1 
ATOM   19385 C CE2 . TRP D 1 703 ? 175.696 106.062 116.183 1.00 90.88  ? 703 TRP D CE2 1 
ATOM   19386 C CE3 . TRP D 1 703 ? 173.496 105.857 117.158 1.00 86.95  ? 703 TRP D CE3 1 
ATOM   19387 C CZ2 . TRP D 1 703 ? 176.145 104.943 116.895 1.00 89.93  ? 703 TRP D CZ2 1 
ATOM   19388 C CZ3 . TRP D 1 703 ? 173.943 104.746 117.893 1.00 88.19  ? 703 TRP D CZ3 1 
ATOM   19389 C CH2 . TRP D 1 703 ? 175.262 104.286 117.765 1.00 87.74  ? 703 TRP D CH2 1 
ATOM   19390 N N   . CYS D 1 704 ? 170.093 107.474 113.151 1.00 77.20  ? 704 CYS D N   1 
ATOM   19391 C CA  . CYS D 1 704 ? 168.681 107.610 112.851 1.00 71.57  ? 704 CYS D CA  1 
ATOM   19392 C C   . CYS D 1 704 ? 167.814 106.983 113.936 1.00 75.70  ? 704 CYS D C   1 
ATOM   19393 O O   . CYS D 1 704 ? 168.164 105.963 114.520 1.00 81.00  ? 704 CYS D O   1 
ATOM   19394 C CB  . CYS D 1 704 ? 168.383 106.933 111.516 1.00 83.40  ? 704 CYS D CB  1 
ATOM   19395 S SG  . CYS D 1 704 ? 168.884 107.998 110.154 1.00 95.63  ? 704 CYS D SG  1 
ATOM   19396 N N   . PHE D 1 705 ? 166.649 107.564 114.168 1.00 63.22  ? 705 PHE D N   1 
ATOM   19397 C CA  . PHE D 1 705 ? 165.666 107.102 115.129 1.00 61.68  ? 705 PHE D CA  1 
ATOM   19398 C C   . PHE D 1 705 ? 164.323 106.856 114.450 1.00 61.21  ? 705 PHE D C   1 
ATOM   19399 O O   . PHE D 1 705 ? 163.765 107.755 113.831 1.00 66.91  ? 705 PHE D O   1 
ATOM   19400 C CB  . PHE D 1 705 ? 165.623 108.159 116.221 1.00 68.31  ? 705 PHE D CB  1 
ATOM   19401 C CG  . PHE D 1 705 ? 164.542 108.004 117.253 1.00 66.77  ? 705 PHE D CG  1 
ATOM   19402 C CD1 . PHE D 1 705 ? 164.731 107.153 118.355 1.00 59.21  ? 705 PHE D CD1 1 
ATOM   19403 C CD2 . PHE D 1 705 ? 163.365 108.754 117.126 1.00 64.46  ? 705 PHE D CD2 1 
ATOM   19404 C CE1 . PHE D 1 705 ? 163.730 107.044 119.329 1.00 56.09  ? 705 PHE D CE1 1 
ATOM   19405 C CE2 . PHE D 1 705 ? 162.375 108.657 118.107 1.00 69.75  ? 705 PHE D CE2 1 
ATOM   19406 C CZ  . PHE D 1 705 ? 162.557 107.796 119.201 1.00 68.11  ? 705 PHE D CZ  1 
ATOM   19407 N N   . ARG D 1 706 ? 163.823 105.616 114.575 1.00 67.78  ? 706 ARG D N   1 
ATOM   19408 C CA  . ARG D 1 706 ? 162.591 105.186 113.854 1.00 67.96  ? 706 ARG D CA  1 
ATOM   19409 C C   . ARG D 1 706 ? 161.308 105.557 114.591 1.00 65.84  ? 706 ARG D C   1 
ATOM   19410 O O   . ARG D 1 706 ? 161.127 105.100 115.737 1.00 76.65  ? 706 ARG D O   1 
ATOM   19411 C CB  . ARG D 1 706 ? 162.653 103.667 113.662 1.00 67.24  ? 706 ARG D CB  1 
ATOM   19412 C CG  . ARG D 1 706 ? 161.468 103.133 112.851 1.00 69.10  ? 706 ARG D CG  1 
ATOM   19413 C CD  . ARG D 1 706 ? 161.582 101.623 112.631 1.00 70.91  ? 706 ARG D CD  1 
ATOM   19414 N NE  . ARG D 1 706 ? 162.620 101.301 111.640 1.00 74.10  ? 706 ARG D NE  1 
ATOM   19415 C CZ  . ARG D 1 706 ? 163.909 101.148 111.921 1.00 77.43  ? 706 ARG D CZ  1 
ATOM   19416 N NH1 . ARG D 1 706 ? 164.767 100.860 110.956 1.00 71.10  ? 706 ARG D NH1 1 
ATOM   19417 N NH2 . ARG D 1 706 ? 164.337 101.288 113.163 1.00 79.03  ? 706 ARG D NH2 1 
ATOM   19418 N N   . VAL D 1 707 ? 160.464 106.351 113.952 1.00 61.83  ? 707 VAL D N   1 
ATOM   19419 C CA  . VAL D 1 707 ? 159.135 106.743 114.436 1.00 64.70  ? 707 VAL D CA  1 
ATOM   19420 C C   . VAL D 1 707 ? 158.085 106.091 113.546 1.00 72.48  ? 707 VAL D C   1 
ATOM   19421 O O   . VAL D 1 707 ? 158.235 106.066 112.330 1.00 81.04  ? 707 VAL D O   1 
ATOM   19422 C CB  . VAL D 1 707 ? 158.977 108.269 114.441 1.00 71.93  ? 707 VAL D CB  1 
ATOM   19423 C CG1 . VAL D 1 707 ? 157.603 108.727 114.932 1.00 69.30  ? 707 VAL D CG1 1 
ATOM   19424 C CG2 . VAL D 1 707 ? 160.027 108.959 115.315 1.00 77.18  ? 707 VAL D CG2 1 
ATOM   19425 N N   . GLU D 1 708 ? 157.020 105.558 114.135 1.00 80.50  ? 708 GLU D N   1 
ATOM   19426 C CA  . GLU D 1 708 ? 155.883 104.981 113.416 1.00 72.25  ? 708 GLU D CA  1 
ATOM   19427 C C   . GLU D 1 708 ? 154.642 105.837 113.688 1.00 73.75  ? 708 GLU D C   1 
ATOM   19428 O O   . GLU D 1 708 ? 154.209 105.957 114.829 1.00 78.33  ? 708 GLU D O   1 
ATOM   19429 C CB  . GLU D 1 708 ? 155.659 103.531 113.858 1.00 71.20  ? 708 GLU D CB  1 
ATOM   19430 C CG  . GLU D 1 708 ? 156.930 102.663 113.864 1.00 76.59  ? 708 GLU D CG  1 
ATOM   19431 C CD  . GLU D 1 708 ? 156.686 101.246 114.397 1.00 87.34  ? 708 GLU D CD  1 
ATOM   19432 O OE1 . GLU D 1 708 ? 155.789 101.054 115.250 1.00 90.26  ? 708 GLU D OE1 1 
ATOM   19433 O OE2 . GLU D 1 708 ? 157.433 100.326 113.999 1.00 85.77  ? 708 GLU D OE2 1 
ATOM   19434 N N   . GLU D 1 709 ? 154.072 106.453 112.659 1.00 87.74  ? 709 GLU D N   1 
ATOM   19435 C CA  . GLU D 1 709 ? 152.876 107.290 112.761 1.00 91.73  ? 709 GLU D CA  1 
ATOM   19436 C C   . GLU D 1 709 ? 151.683 106.568 112.140 1.00 96.11  ? 709 GLU D C   1 
ATOM   19437 O O   . GLU D 1 709 ? 151.743 106.178 110.977 1.00 99.11  ? 709 GLU D O   1 
ATOM   19438 C CB  . GLU D 1 709 ? 153.121 108.643 112.067 1.00 89.53  ? 709 GLU D CB  1 
ATOM   19439 C CG  . GLU D 1 709 ? 151.873 109.544 112.075 1.00 90.00  ? 709 GLU D CG  1 
ATOM   19440 C CD  . GLU D 1 709 ? 152.005 110.851 111.274 1.00 100.24 ? 709 GLU D CD  1 
ATOM   19441 O OE1 . GLU D 1 709 ? 153.060 111.106 110.652 1.00 100.62 ? 709 GLU D OE1 1 
ATOM   19442 O OE2 . GLU D 1 709 ? 151.026 111.632 111.263 1.00 100.48 ? 709 GLU D OE2 1 
ATOM   19443 N N   . VAL D 1 710 ? 150.580 106.445 112.879 1.00 87.97  ? 710 VAL D N   1 
ATOM   19444 C CA  . VAL D 1 710 ? 149.281 106.020 112.350 1.00 83.93  ? 710 VAL D CA  1 
ATOM   19445 C C   . VAL D 1 710 ? 148.367 107.236 112.306 1.00 85.74  ? 710 VAL D C   1 
ATOM   19446 O O   . VAL D 1 710 ? 148.148 107.879 113.331 1.00 84.32  ? 710 VAL D O   1 
ATOM   19447 C CB  . VAL D 1 710 ? 148.656 104.914 113.210 1.00 83.01  ? 710 VAL D CB  1 
ATOM   19448 C CG1 . VAL D 1 710 ? 147.371 104.396 112.563 1.00 85.34  ? 710 VAL D CG1 1 
ATOM   19449 C CG2 . VAL D 1 710 ? 149.609 103.737 113.422 1.00 83.87  ? 710 VAL D CG2 1 
ATOM   19450 N N   . ASN D 1 711 ? 147.826 107.575 111.136 1.00 87.87  ? 711 ASN D N   1 
ATOM   19451 C CA  . ASN D 1 711 ? 147.048 108.800 110.958 1.00 84.19  ? 711 ASN D CA  1 
ATOM   19452 C C   . ASN D 1 711 ? 145.953 108.627 109.895 1.00 87.58  ? 711 ASN D C   1 
ATOM   19453 O O   . ASN D 1 711 ? 146.091 109.049 108.749 1.00 91.60  ? 711 ASN D O   1 
ATOM   19454 C CB  . ASN D 1 711 ? 148.032 109.940 110.656 1.00 86.19  ? 711 ASN D CB  1 
ATOM   19455 C CG  . ASN D 1 711 ? 147.426 111.321 110.796 1.00 85.84  ? 711 ASN D CG  1 
ATOM   19456 O OD1 . ASN D 1 711 ? 146.223 111.524 110.714 1.00 82.47  ? 711 ASN D OD1 1 
ATOM   19457 N ND2 . ASN D 1 711 ? 148.249 112.311 111.033 1.00 86.59  ? 711 ASN D ND2 1 
ATOM   19458 N N   . TRP D 1 712 ? 144.841 108.000 110.282 1.00 86.47  ? 712 TRP D N   1 
ATOM   19459 C CA  . TRP D 1 712 ? 143.670 107.823 109.425 1.00 86.45  ? 712 TRP D CA  1 
ATOM   19460 C C   . TRP D 1 712 ? 143.116 109.156 108.919 1.00 86.82  ? 712 TRP D C   1 
ATOM   19461 O O   . TRP D 1 712 ? 142.876 109.303 107.726 1.00 85.16  ? 712 TRP D O   1 
ATOM   19462 C CB  . TRP D 1 712 ? 142.583 107.077 110.201 1.00 85.35  ? 712 TRP D CB  1 
ATOM   19463 C CG  . TRP D 1 712 ? 142.780 105.607 110.376 1.00 87.86  ? 712 TRP D CG  1 
ATOM   19464 C CD1 . TRP D 1 712 ? 143.502 105.006 111.348 1.00 85.41  ? 712 TRP D CD1 1 
ATOM   19465 C CD2 . TRP D 1 712 ? 142.205 104.528 109.580 1.00 88.43  ? 712 TRP D CD2 1 
ATOM   19466 N NE1 . TRP D 1 712 ? 143.421 103.636 111.201 1.00 88.31  ? 712 TRP D NE1 1 
ATOM   19467 C CE2 . TRP D 1 712 ? 142.612 103.286 110.144 1.00 90.52  ? 712 TRP D CE2 1 
ATOM   19468 C CE3 . TRP D 1 712 ? 141.346 104.479 108.466 1.00 81.59  ? 712 TRP D CE3 1 
ATOM   19469 C CZ2 . TRP D 1 712 ? 142.188 102.056 109.623 1.00 84.27  ? 712 TRP D CZ2 1 
ATOM   19470 C CZ3 . TRP D 1 712 ? 140.923 103.249 107.932 1.00 83.54  ? 712 TRP D CZ3 1 
ATOM   19471 C CH2 . TRP D 1 712 ? 141.338 102.041 108.508 1.00 83.24  ? 712 TRP D CH2 1 
ATOM   19472 N N   . ALA D 1 713 ? 142.958 110.145 109.799 1.00 94.42  ? 713 ALA D N   1 
ATOM   19473 C CA  . ALA D 1 713 ? 142.359 111.430 109.448 1.00 91.36  ? 713 ALA D CA  1 
ATOM   19474 C C   . ALA D 1 713 ? 143.129 112.170 108.339 1.00 92.22  ? 713 ALA D C   1 
ATOM   19475 O O   . ALA D 1 713 ? 142.507 112.726 107.438 1.00 92.30  ? 713 ALA D O   1 
ATOM   19476 C CB  . ALA D 1 713 ? 142.257 112.269 110.725 1.00 85.85  ? 713 ALA D CB  1 
ATOM   19477 N N   . ALA D 1 714 ? 144.467 112.153 108.361 1.00 90.05  ? 714 ALA D N   1 
ATOM   19478 C CA  . ALA D 1 714 ? 145.278 112.726 107.288 1.00 87.12  ? 714 ALA D CA  1 
ATOM   19479 C C   . ALA D 1 714 ? 145.326 111.827 106.045 1.00 88.26  ? 714 ALA D C   1 
ATOM   19480 O O   . ALA D 1 714 ? 145.261 112.322 104.926 1.00 90.67  ? 714 ALA D O   1 
ATOM   19481 C CB  . ALA D 1 714 ? 146.688 112.990 107.817 1.00 84.78  ? 714 ALA D CB  1 
ATOM   19482 N N   . TRP D 1 715 ? 145.422 110.510 106.217 1.00 84.17  ? 715 TRP D N   1 
ATOM   19483 C CA  . TRP D 1 715 ? 145.530 109.559 105.107 1.00 84.69  ? 715 TRP D CA  1 
ATOM   19484 C C   . TRP D 1 715 ? 144.273 109.495 104.247 1.00 88.46  ? 715 TRP D C   1 
ATOM   19485 O O   . TRP D 1 715 ? 144.373 109.521 103.022 1.00 89.67  ? 715 TRP D O   1 
ATOM   19486 C CB  . TRP D 1 715 ? 145.872 108.180 105.662 1.00 81.95  ? 715 TRP D CB  1 
ATOM   19487 C CG  . TRP D 1 715 ? 145.770 107.052 104.691 1.00 83.22  ? 715 TRP D CG  1 
ATOM   19488 C CD1 . TRP D 1 715 ? 146.593 106.832 103.643 1.00 81.89  ? 715 TRP D CD1 1 
ATOM   19489 C CD2 . TRP D 1 715 ? 144.785 105.984 104.656 1.00 88.24  ? 715 TRP D CD2 1 
ATOM   19490 N NE1 . TRP D 1 715 ? 146.206 105.683 102.989 1.00 80.87  ? 715 TRP D NE1 1 
ATOM   19491 C CE2 . TRP D 1 715 ? 145.123 105.092 103.601 1.00 86.35  ? 715 TRP D CE2 1 
ATOM   19492 C CE3 . TRP D 1 715 ? 143.655 105.663 105.434 1.00 81.81  ? 715 TRP D CE3 1 
ATOM   19493 C CZ2 . TRP D 1 715 ? 144.407 103.919 103.353 1.00 76.99  ? 715 TRP D CZ2 1 
ATOM   19494 C CZ3 . TRP D 1 715 ? 142.915 104.499 105.178 1.00 78.21  ? 715 TRP D CZ3 1 
ATOM   19495 C CH2 . TRP D 1 715 ? 143.296 103.619 104.158 1.00 76.26  ? 715 TRP D CH2 1 
ATOM   19496 N N   . GLU D 1 716 ? 143.083 109.480 104.843 1.00 100.43 ? 716 GLU D N   1 
ATOM   19497 C CA  . GLU D 1 716 ? 141.827 109.371 104.100 1.00 96.93  ? 716 GLU D CA  1 
ATOM   19498 C C   . GLU D 1 716 ? 141.595 110.529 103.122 1.00 99.64  ? 716 GLU D C   1 
ATOM   19499 O O   . GLU D 1 716 ? 140.989 110.347 102.070 1.00 99.53  ? 716 GLU D O   1 
ATOM   19500 C CB  . GLU D 1 716 ? 140.652 109.278 105.068 1.00 99.73  ? 716 GLU D CB  1 
ATOM   19501 C CG  . GLU D 1 716 ? 140.584 107.889 105.699 1.00 104.20 ? 716 GLU D CG  1 
ATOM   19502 C CD  . GLU D 1 716 ? 139.275 107.743 106.468 1.00 106.26 ? 716 GLU D CD  1 
ATOM   19503 O OE1 . GLU D 1 716 ? 139.187 108.199 107.624 1.00 103.79 ? 716 GLU D OE1 1 
ATOM   19504 O OE2 . GLU D 1 716 ? 138.315 107.193 105.889 1.00 102.75 ? 716 GLU D OE2 1 
ATOM   19505 N N   . LYS D 1 717 ? 142.138 111.710 103.430 1.00 102.47 ? 717 LYS D N   1 
ATOM   19506 C CA  . LYS D 1 717 ? 142.100 112.901 102.570 1.00 102.53 ? 717 LYS D CA  1 
ATOM   19507 C C   . LYS D 1 717 ? 142.973 112.775 101.312 1.00 100.79 ? 717 LYS D C   1 
ATOM   19508 O O   . LYS D 1 717 ? 142.816 113.562 100.384 1.00 101.92 ? 717 LYS D O   1 
ATOM   19509 C CB  . LYS D 1 717 ? 142.479 114.128 103.415 1.00 98.34  ? 717 LYS D CB  1 
ATOM   19510 C CG  . LYS D 1 717 ? 141.459 114.361 104.541 1.00 100.11 ? 717 LYS D CG  1 
ATOM   19511 C CD  . LYS D 1 717 ? 141.894 115.475 105.498 1.00 103.56 ? 717 LYS D CD  1 
ATOM   19512 C CE  . LYS D 1 717 ? 140.890 115.543 106.654 1.00 101.38 ? 717 LYS D CE  1 
ATOM   19513 N NZ  . LYS D 1 717 ? 141.256 116.587 107.639 1.00 98.96  ? 717 LYS D NZ  1 
ATOM   19514 N N   . THR D 1 718 ? 143.861 111.779 101.253 1.00 96.19  ? 718 THR D N   1 
ATOM   19515 C CA  . THR D 1 718 ? 144.709 111.469 100.084 1.00 98.31  ? 718 THR D CA  1 
ATOM   19516 C C   . THR D 1 718 ? 144.134 110.383 99.165  1.00 98.85  ? 718 THR D C   1 
ATOM   19517 O O   . THR D 1 718 ? 144.678 110.145 98.087  1.00 97.12  ? 718 THR D O   1 
ATOM   19518 C CB  . THR D 1 718 ? 146.134 111.070 100.504 1.00 103.64 ? 718 THR D CB  1 
ATOM   19519 O OG1 . THR D 1 718 ? 146.192 109.771 101.051 1.00 101.46 ? 718 THR D OG1 1 
ATOM   19520 C CG2 . THR D 1 718 ? 146.744 112.029 101.519 1.00 99.41  ? 718 THR D CG2 1 
ATOM   19521 N N   . LEU D 1 719 ? 143.051 109.704 99.557  1.00 100.28 ? 719 LEU D N   1 
ATOM   19522 C CA  . LEU D 1 719 ? 142.477 108.597 98.789  1.00 103.20 ? 719 LEU D CA  1 
ATOM   19523 C C   . LEU D 1 719 ? 141.895 109.066 97.444  1.00 100.32 ? 719 LEU D C   1 
ATOM   19524 O O   . LEU D 1 719 ? 140.849 109.718 97.382  1.00 99.11  ? 719 LEU D O   1 
ATOM   19525 C CB  . LEU D 1 719 ? 141.458 107.824 99.651  1.00 100.14 ? 719 LEU D CB  1 
ATOM   19526 C CG  . LEU D 1 719 ? 142.031 107.232 100.953 1.00 96.94  ? 719 LEU D CG  1 
ATOM   19527 C CD1 . LEU D 1 719 ? 140.944 106.489 101.721 1.00 97.03  ? 719 LEU D CD1 1 
ATOM   19528 C CD2 . LEU D 1 719 ? 143.164 106.252 100.707 1.00 92.34  ? 719 LEU D CD2 1 
HETATM 19529 O O1  . PEX E 2 .   ? 113.740 99.824  141.528 1.00 84.67  ? 801 PEX A O1  1 
HETATM 19530 O O2  . PEX E 2 .   ? 114.932 97.893  142.384 1.00 82.61  ? 801 PEX A O2  1 
HETATM 19531 P P1  . PEX E 2 .   ? 114.647 99.330  142.588 1.00 98.69  ? 801 PEX A P1  1 
HETATM 19532 O O3  . PEX E 2 .   ? 114.025 99.624  144.032 1.00 87.54  ? 801 PEX A O3  1 
HETATM 19533 C C1  . PEX E 2 .   ? 114.205 98.688  145.108 1.00 75.06  ? 801 PEX A C1  1 
HETATM 19534 C C2  . PEX E 2 .   ? 113.140 98.987  146.177 1.00 72.85  ? 801 PEX A C2  1 
HETATM 19535 C C3  . PEX E 2 .   ? 111.718 98.697  145.656 1.00 77.28  ? 801 PEX A C3  1 
HETATM 19536 O O4  . PEX E 2 .   ? 111.481 97.277  145.640 1.00 78.37  ? 801 PEX A O4  1 
HETATM 19537 C C4  . PEX E 2 .   ? 110.196 96.835  145.540 1.00 82.13  ? 801 PEX A C4  1 
HETATM 19538 O O5  . PEX E 2 .   ? 109.226 97.568  145.559 1.00 85.15  ? 801 PEX A O5  1 
HETATM 19539 C C5  . PEX E 2 .   ? 110.129 95.347  145.825 1.00 79.06  ? 801 PEX A C5  1 
HETATM 19540 C C6  . PEX E 2 .   ? 108.847 94.886  146.553 1.00 81.19  ? 801 PEX A C6  1 
HETATM 19541 C C7  . PEX E 2 .   ? 109.070 93.507  147.213 1.00 87.88  ? 801 PEX A C7  1 
HETATM 19542 C C8  . PEX E 2 .   ? 107.797 92.955  147.887 1.00 83.85  ? 801 PEX A C8  1 
HETATM 19543 C C9  . PEX E 2 .   ? 108.066 91.733  148.804 1.00 83.16  ? 801 PEX A C9  1 
HETATM 19544 C C10 . PEX E 2 .   ? 108.664 90.508  148.071 1.00 85.80  ? 801 PEX A C10 1 
HETATM 19545 C C11 . PEX E 2 .   ? 108.736 89.266  148.989 1.00 81.32  ? 801 PEX A C11 1 
HETATM 19546 C C12 . PEX E 2 .   ? 109.402 88.040  148.324 1.00 82.64  ? 801 PEX A C12 1 
HETATM 19547 C C13 . PEX E 2 .   ? 110.935 88.150  148.246 1.00 82.39  ? 801 PEX A C13 1 
HETATM 19548 O O6  . PEX E 2 .   ? 113.390 98.162  147.340 1.00 88.06  ? 801 PEX A O6  1 
HETATM 19549 C C14 . PEX E 2 .   ? 112.777 98.498  148.510 1.00 84.92  ? 801 PEX A C14 1 
HETATM 19550 O O7  . PEX E 2 .   ? 112.153 99.524  148.676 1.00 89.60  ? 801 PEX A O7  1 
HETATM 19551 C C15 . PEX E 2 .   ? 112.971 97.473  149.609 1.00 73.04  ? 801 PEX A C15 1 
HETATM 19552 C C16 . PEX E 2 .   ? 111.801 96.458  149.646 1.00 81.03  ? 801 PEX A C16 1 
HETATM 19553 C C17 . PEX E 2 .   ? 111.335 96.139  151.080 1.00 83.77  ? 801 PEX A C17 1 
HETATM 19554 C C18 . PEX E 2 .   ? 110.415 97.233  151.681 1.00 86.09  ? 801 PEX A C18 1 
HETATM 19555 C C19 . PEX E 2 .   ? 108.945 97.102  151.221 1.00 83.67  ? 801 PEX A C19 1 
HETATM 19556 C C20 . PEX E 2 .   ? 108.045 98.213  151.800 1.00 79.32  ? 801 PEX A C20 1 
HETATM 19557 C C21 . PEX E 2 .   ? 106.591 98.078  151.290 1.00 82.84  ? 801 PEX A C21 1 
HETATM 19558 C C22 . PEX E 2 .   ? 105.733 99.320  151.611 1.00 84.52  ? 801 PEX A C22 1 
HETATM 19559 C C23 . PEX E 2 .   ? 104.382 99.304  150.872 1.00 77.04  ? 801 PEX A C23 1 
HETATM 19560 O O8  . PEX E 2 .   ? 115.977 100.236 142.617 1.00 85.45  ? 801 PEX A O8  1 
HETATM 19561 C C24 . PEX E 2 .   ? 117.170 99.845  143.321 1.00 76.11  ? 801 PEX A C24 1 
HETATM 19562 C C25 . PEX E 2 .   ? 118.339 100.713 142.785 1.00 71.32  ? 801 PEX A C25 1 
HETATM 19563 N N1  . PEX E 2 .   ? 118.887 100.291 141.421 1.00 71.11  ? 801 PEX A N1  1 
HETATM 19564 C C13 . RTO F 3 .   ? 155.326 99.856  101.815 1.00 104.69 ? 802 RTO A C13 1 
HETATM 19565 C C15 . RTO F 3 .   ? 157.592 99.059  101.575 1.00 99.68  ? 802 RTO A C15 1 
HETATM 19566 C C17 . RTO F 3 .   ? 157.013 101.374 100.860 1.00 104.59 ? 802 RTO A C17 1 
HETATM 19567 C C01 . RTO F 3 .   ? 152.512 95.261  106.345 1.00 97.78  ? 802 RTO A C01 1 
HETATM 19568 C C02 . RTO F 3 .   ? 153.547 96.350  106.600 1.00 97.39  ? 802 RTO A C02 1 
HETATM 19569 C C03 . RTO F 3 .   ? 153.958 96.960  105.270 1.00 97.16  ? 802 RTO A C03 1 
HETATM 19570 C C05 . RTO F 3 .   ? 156.382 96.516  105.614 1.00 100.60 ? 802 RTO A C05 1 
HETATM 19571 C C06 . RTO F 3 .   ? 156.835 95.199  106.224 1.00 99.83  ? 802 RTO A C06 1 
HETATM 19572 C C07 . RTO F 3 .   ? 158.007 95.498  107.151 1.00 100.59 ? 802 RTO A C07 1 
HETATM 19573 C C11 . RTO F 3 .   ? 155.901 97.650  102.499 1.00 103.62 ? 802 RTO A C11 1 
HETATM 19574 C C12 . RTO F 3 .   ? 154.963 98.642  102.342 1.00 102.64 ? 802 RTO A C12 1 
HETATM 19575 C C14 . RTO F 3 .   ? 156.644 100.070 101.426 1.00 104.45 ? 802 RTO A C14 1 
HETATM 19576 C C16 . RTO F 3 .   ? 157.211 97.848  102.108 1.00 101.15 ? 802 RTO A C16 1 
HETATM 19577 N N04 . RTO F 3 .   ? 155.186 96.321  104.804 1.00 102.62 ? 802 RTO A N04 1 
HETATM 19578 O O09 . RTO F 3 .   ? 154.062 95.987  102.659 1.00 108.09 ? 802 RTO A O09 1 
HETATM 19579 O O10 . RTO F 3 .   ? 156.381 95.167  102.953 1.00 105.69 ? 802 RTO A O10 1 
HETATM 19580 O O18 . RTO F 3 .   ? 156.179 102.252 100.783 1.00 102.85 ? 802 RTO A O18 1 
HETATM 19581 O O19 . RTO F 3 .   ? 158.265 101.587 100.426 1.00 103.44 ? 802 RTO A O19 1 
HETATM 19582 S S08 . RTO F 3 .   ? 155.364 96.126  103.173 1.00 113.98 ? 802 RTO A S08 1 
HETATM 19583 O O1  . PEX G 2 .   ? 99.824  151.860 141.528 1.00 84.67  ? 801 PEX B O1  1 
HETATM 19584 O O2  . PEX G 2 .   ? 97.893  150.668 142.384 1.00 82.61  ? 801 PEX B O2  1 
HETATM 19585 P P1  . PEX G 2 .   ? 99.330  150.953 142.588 1.00 98.69  ? 801 PEX B P1  1 
HETATM 19586 O O3  . PEX G 2 .   ? 99.624  151.575 144.032 1.00 87.54  ? 801 PEX B O3  1 
HETATM 19587 C C1  . PEX G 2 .   ? 98.687  151.395 145.108 1.00 75.06  ? 801 PEX B C1  1 
HETATM 19588 C C2  . PEX G 2 .   ? 98.986  152.460 146.177 1.00 72.85  ? 801 PEX B C2  1 
HETATM 19589 C C3  . PEX G 2 .   ? 98.696  153.882 145.656 1.00 77.28  ? 801 PEX B C3  1 
HETATM 19590 O O4  . PEX G 2 .   ? 97.276  154.119 145.640 1.00 78.37  ? 801 PEX B O4  1 
HETATM 19591 C C4  . PEX G 2 .   ? 96.834  155.404 145.540 1.00 82.13  ? 801 PEX B C4  1 
HETATM 19592 O O5  . PEX G 2 .   ? 97.567  156.374 145.559 1.00 85.15  ? 801 PEX B O5  1 
HETATM 19593 C C5  . PEX G 2 .   ? 95.346  155.471 145.825 1.00 79.06  ? 801 PEX B C5  1 
HETATM 19594 C C6  . PEX G 2 .   ? 94.885  156.753 146.553 1.00 81.19  ? 801 PEX B C6  1 
HETATM 19595 C C7  . PEX G 2 .   ? 93.506  156.530 147.213 1.00 87.88  ? 801 PEX B C7  1 
HETATM 19596 C C8  . PEX G 2 .   ? 92.954  157.803 147.887 1.00 83.85  ? 801 PEX B C8  1 
HETATM 19597 C C9  . PEX G 2 .   ? 91.732  157.534 148.804 1.00 83.16  ? 801 PEX B C9  1 
HETATM 19598 C C10 . PEX G 2 .   ? 90.507  156.936 148.071 1.00 85.80  ? 801 PEX B C10 1 
HETATM 19599 C C11 . PEX G 2 .   ? 89.265  156.864 148.989 1.00 81.32  ? 801 PEX B C11 1 
HETATM 19600 C C12 . PEX G 2 .   ? 88.039  156.198 148.324 1.00 82.64  ? 801 PEX B C12 1 
HETATM 19601 C C13 . PEX G 2 .   ? 88.149  154.665 148.246 1.00 82.39  ? 801 PEX B C13 1 
HETATM 19602 O O6  . PEX G 2 .   ? 98.161  152.210 147.340 1.00 88.06  ? 801 PEX B O6  1 
HETATM 19603 C C14 . PEX G 2 .   ? 98.497  152.823 148.510 1.00 84.92  ? 801 PEX B C14 1 
HETATM 19604 O O7  . PEX G 2 .   ? 99.523  153.447 148.676 1.00 89.60  ? 801 PEX B O7  1 
HETATM 19605 C C15 . PEX G 2 .   ? 97.472  152.629 149.609 1.00 73.04  ? 801 PEX B C15 1 
HETATM 19606 C C16 . PEX G 2 .   ? 96.457  153.799 149.646 1.00 81.03  ? 801 PEX B C16 1 
HETATM 19607 C C17 . PEX G 2 .   ? 96.138  154.265 151.080 1.00 83.77  ? 801 PEX B C17 1 
HETATM 19608 C C18 . PEX G 2 .   ? 97.232  155.185 151.681 1.00 86.09  ? 801 PEX B C18 1 
HETATM 19609 C C19 . PEX G 2 .   ? 97.101  156.655 151.221 1.00 83.67  ? 801 PEX B C19 1 
HETATM 19610 C C20 . PEX G 2 .   ? 98.212  157.555 151.800 1.00 79.32  ? 801 PEX B C20 1 
HETATM 19611 C C21 . PEX G 2 .   ? 98.077  159.009 151.290 1.00 82.84  ? 801 PEX B C21 1 
HETATM 19612 C C22 . PEX G 2 .   ? 99.319  159.867 151.611 1.00 84.52  ? 801 PEX B C22 1 
HETATM 19613 C C23 . PEX G 2 .   ? 99.303  161.218 150.872 1.00 77.04  ? 801 PEX B C23 1 
HETATM 19614 O O8  . PEX G 2 .   ? 100.236 149.623 142.617 1.00 85.45  ? 801 PEX B O8  1 
HETATM 19615 C C24 . PEX G 2 .   ? 99.845  148.430 143.321 1.00 76.11  ? 801 PEX B C24 1 
HETATM 19616 C C25 . PEX G 2 .   ? 100.713 147.261 142.785 1.00 71.32  ? 801 PEX B C25 1 
HETATM 19617 N N1  . PEX G 2 .   ? 100.291 146.713 141.421 1.00 71.11  ? 801 PEX B N1  1 
HETATM 19618 C C13 . RTO H 3 .   ? 99.857  110.273 101.815 1.00 104.69 ? 802 RTO B C13 1 
HETATM 19619 C C15 . RTO H 3 .   ? 99.061  108.008 101.575 1.00 99.68  ? 802 RTO B C15 1 
HETATM 19620 C C17 . RTO H 3 .   ? 101.376 108.587 100.860 1.00 104.59 ? 802 RTO B C17 1 
HETATM 19621 C C01 . RTO H 3 .   ? 95.263  113.088 106.345 1.00 97.78  ? 802 RTO B C01 1 
HETATM 19622 C C02 . RTO H 3 .   ? 96.352  112.053 106.600 1.00 97.39  ? 802 RTO B C02 1 
HETATM 19623 C C03 . RTO H 3 .   ? 96.962  111.641 105.270 1.00 97.16  ? 802 RTO B C03 1 
HETATM 19624 C C05 . RTO H 3 .   ? 96.517  109.217 105.614 1.00 100.60 ? 802 RTO B C05 1 
HETATM 19625 C C06 . RTO H 3 .   ? 95.200  108.764 106.224 1.00 99.83  ? 802 RTO B C06 1 
HETATM 19626 C C07 . RTO H 3 .   ? 95.500  107.593 107.152 1.00 100.59 ? 802 RTO B C07 1 
HETATM 19627 C C11 . RTO H 3 .   ? 97.652  109.698 102.499 1.00 103.62 ? 802 RTO B C11 1 
HETATM 19628 C C12 . RTO H 3 .   ? 98.644  110.637 102.343 1.00 102.64 ? 802 RTO B C12 1 
HETATM 19629 C C14 . RTO H 3 .   ? 100.071 108.956 101.427 1.00 104.45 ? 802 RTO B C14 1 
HETATM 19630 C C16 . RTO H 3 .   ? 97.850  108.388 102.108 1.00 101.15 ? 802 RTO B C16 1 
HETATM 19631 N N04 . RTO H 3 .   ? 96.323  110.414 104.804 1.00 102.62 ? 802 RTO B N04 1 
HETATM 19632 O O09 . RTO H 3 .   ? 95.988  111.537 102.659 1.00 108.09 ? 802 RTO B O09 1 
HETATM 19633 O O10 . RTO H 3 .   ? 95.168  109.218 102.954 1.00 105.69 ? 802 RTO B O10 1 
HETATM 19634 O O18 . RTO H 3 .   ? 102.254 109.420 100.784 1.00 102.85 ? 802 RTO B O18 1 
HETATM 19635 O O19 . RTO H 3 .   ? 101.589 107.334 100.426 1.00 103.44 ? 802 RTO B O19 1 
HETATM 19636 S S08 . RTO H 3 .   ? 96.128  110.235 103.173 1.00 113.98 ? 802 RTO B S08 1 
HETATM 19637 O O1  . PEX I 2 .   ? 151.860 165.776 141.528 1.00 84.67  ? 801 PEX C O1  1 
HETATM 19638 O O2  . PEX I 2 .   ? 150.668 167.707 142.384 1.00 82.61  ? 801 PEX C O2  1 
HETATM 19639 P P1  . PEX I 2 .   ? 150.953 166.270 142.588 1.00 98.69  ? 801 PEX C P1  1 
HETATM 19640 O O3  . PEX I 2 .   ? 151.575 165.977 144.032 1.00 87.54  ? 801 PEX C O3  1 
HETATM 19641 C C1  . PEX I 2 .   ? 151.395 166.913 145.108 1.00 75.06  ? 801 PEX C C1  1 
HETATM 19642 C C2  . PEX I 2 .   ? 152.460 166.614 146.177 1.00 72.85  ? 801 PEX C C2  1 
HETATM 19643 C C3  . PEX I 2 .   ? 153.882 166.904 145.656 1.00 77.28  ? 801 PEX C C3  1 
HETATM 19644 O O4  . PEX I 2 .   ? 154.119 168.324 145.640 1.00 78.37  ? 801 PEX C O4  1 
HETATM 19645 C C4  . PEX I 2 .   ? 155.404 168.766 145.540 1.00 82.13  ? 801 PEX C C4  1 
HETATM 19646 O O5  . PEX I 2 .   ? 156.374 168.033 145.559 1.00 85.15  ? 801 PEX C O5  1 
HETATM 19647 C C5  . PEX I 2 .   ? 155.471 170.254 145.825 1.00 79.06  ? 801 PEX C C5  1 
HETATM 19648 C C6  . PEX I 2 .   ? 156.753 170.715 146.553 1.00 81.19  ? 801 PEX C C6  1 
HETATM 19649 C C7  . PEX I 2 .   ? 156.530 172.094 147.213 1.00 87.88  ? 801 PEX C C7  1 
HETATM 19650 C C8  . PEX I 2 .   ? 157.803 172.646 147.887 1.00 83.85  ? 801 PEX C C8  1 
HETATM 19651 C C9  . PEX I 2 .   ? 157.534 173.868 148.804 1.00 83.16  ? 801 PEX C C9  1 
HETATM 19652 C C10 . PEX I 2 .   ? 156.936 175.093 148.071 1.00 85.80  ? 801 PEX C C10 1 
HETATM 19653 C C11 . PEX I 2 .   ? 156.864 176.335 148.989 1.00 81.32  ? 801 PEX C C11 1 
HETATM 19654 C C12 . PEX I 2 .   ? 156.198 177.561 148.324 1.00 82.64  ? 801 PEX C C12 1 
HETATM 19655 C C13 . PEX I 2 .   ? 154.665 177.451 148.246 1.00 82.39  ? 801 PEX C C13 1 
HETATM 19656 O O6  . PEX I 2 .   ? 152.210 167.439 147.340 1.00 88.06  ? 801 PEX C O6  1 
HETATM 19657 C C14 . PEX I 2 .   ? 152.823 167.103 148.510 1.00 84.92  ? 801 PEX C C14 1 
HETATM 19658 O O7  . PEX I 2 .   ? 153.447 166.077 148.676 1.00 89.60  ? 801 PEX C O7  1 
HETATM 19659 C C15 . PEX I 2 .   ? 152.629 168.128 149.609 1.00 73.04  ? 801 PEX C C15 1 
HETATM 19660 C C16 . PEX I 2 .   ? 153.799 169.143 149.646 1.00 81.03  ? 801 PEX C C16 1 
HETATM 19661 C C17 . PEX I 2 .   ? 154.265 169.462 151.080 1.00 83.77  ? 801 PEX C C17 1 
HETATM 19662 C C18 . PEX I 2 .   ? 155.185 168.368 151.681 1.00 86.09  ? 801 PEX C C18 1 
HETATM 19663 C C19 . PEX I 2 .   ? 156.655 168.499 151.221 1.00 83.67  ? 801 PEX C C19 1 
HETATM 19664 C C20 . PEX I 2 .   ? 157.555 167.388 151.800 1.00 79.32  ? 801 PEX C C20 1 
HETATM 19665 C C21 . PEX I 2 .   ? 159.009 167.523 151.290 1.00 82.84  ? 801 PEX C C21 1 
HETATM 19666 C C22 . PEX I 2 .   ? 159.867 166.281 151.611 1.00 84.52  ? 801 PEX C C22 1 
HETATM 19667 C C23 . PEX I 2 .   ? 161.218 166.297 150.872 1.00 77.04  ? 801 PEX C C23 1 
HETATM 19668 O O8  . PEX I 2 .   ? 149.623 165.364 142.617 1.00 85.45  ? 801 PEX C O8  1 
HETATM 19669 C C24 . PEX I 2 .   ? 148.430 165.755 143.321 1.00 76.11  ? 801 PEX C C24 1 
HETATM 19670 C C25 . PEX I 2 .   ? 147.261 164.887 142.785 1.00 71.32  ? 801 PEX C C25 1 
HETATM 19671 N N1  . PEX I 2 .   ? 146.713 165.309 141.421 1.00 71.11  ? 801 PEX C N1  1 
HETATM 19672 C C13 . RTO J 3 .   ? 110.273 165.742 101.815 1.00 104.69 ? 802 RTO C C13 1 
HETATM 19673 C C15 . RTO J 3 .   ? 108.008 166.539 101.575 1.00 99.68  ? 802 RTO C C15 1 
HETATM 19674 C C17 . RTO J 3 .   ? 108.587 164.224 100.860 1.00 104.59 ? 802 RTO C C17 1 
HETATM 19675 C C01 . RTO J 3 .   ? 113.088 170.337 106.345 1.00 97.78  ? 802 RTO C C01 1 
HETATM 19676 C C02 . RTO J 3 .   ? 112.053 169.248 106.600 1.00 97.39  ? 802 RTO C C02 1 
HETATM 19677 C C03 . RTO J 3 .   ? 111.641 168.638 105.270 1.00 97.16  ? 802 RTO C C03 1 
HETATM 19678 C C05 . RTO J 3 .   ? 109.217 169.082 105.614 1.00 100.60 ? 802 RTO C C05 1 
HETATM 19679 C C06 . RTO J 3 .   ? 108.764 170.400 106.224 1.00 99.83  ? 802 RTO C C06 1 
HETATM 19680 C C07 . RTO J 3 .   ? 107.593 170.100 107.152 1.00 100.59 ? 802 RTO C C07 1 
HETATM 19681 C C11 . RTO J 3 .   ? 109.698 167.948 102.499 1.00 103.62 ? 802 RTO C C11 1 
HETATM 19682 C C12 . RTO J 3 .   ? 110.637 166.956 102.343 1.00 102.64 ? 802 RTO C C12 1 
HETATM 19683 C C14 . RTO J 3 .   ? 108.956 165.528 101.427 1.00 104.45 ? 802 RTO C C14 1 
HETATM 19684 C C16 . RTO J 3 .   ? 108.388 167.750 102.108 1.00 101.15 ? 802 RTO C C16 1 
HETATM 19685 N N04 . RTO J 3 .   ? 110.414 169.277 104.804 1.00 102.62 ? 802 RTO C N04 1 
HETATM 19686 O O09 . RTO J 3 .   ? 111.537 169.611 102.659 1.00 108.09 ? 802 RTO C O09 1 
HETATM 19687 O O10 . RTO J 3 .   ? 109.218 170.431 102.954 1.00 105.69 ? 802 RTO C O10 1 
HETATM 19688 O O18 . RTO J 3 .   ? 109.420 163.346 100.784 1.00 102.85 ? 802 RTO C O18 1 
HETATM 19689 O O19 . RTO J 3 .   ? 107.334 164.011 100.426 1.00 103.44 ? 802 RTO C O19 1 
HETATM 19690 S S08 . RTO J 3 .   ? 110.235 169.472 103.173 1.00 113.98 ? 802 RTO C S08 1 
HETATM 19691 O O1  . PEX K 2 .   ? 165.776 113.740 141.528 1.00 84.67  ? 801 PEX D O1  1 
HETATM 19692 O O2  . PEX K 2 .   ? 167.707 114.932 142.384 1.00 82.61  ? 801 PEX D O2  1 
HETATM 19693 P P1  . PEX K 2 .   ? 166.270 114.647 142.588 1.00 98.69  ? 801 PEX D P1  1 
HETATM 19694 O O3  . PEX K 2 .   ? 165.976 114.025 144.032 1.00 87.54  ? 801 PEX D O3  1 
HETATM 19695 C C1  . PEX K 2 .   ? 166.913 114.205 145.108 1.00 75.06  ? 801 PEX D C1  1 
HETATM 19696 C C2  . PEX K 2 .   ? 166.614 113.140 146.177 1.00 72.85  ? 801 PEX D C2  1 
HETATM 19697 C C3  . PEX K 2 .   ? 166.904 111.718 145.656 1.00 77.28  ? 801 PEX D C3  1 
HETATM 19698 O O4  . PEX K 2 .   ? 168.324 111.481 145.640 1.00 78.37  ? 801 PEX D O4  1 
HETATM 19699 C C4  . PEX K 2 .   ? 168.766 110.196 145.540 1.00 82.13  ? 801 PEX D C4  1 
HETATM 19700 O O5  . PEX K 2 .   ? 168.033 109.226 145.559 1.00 85.15  ? 801 PEX D O5  1 
HETATM 19701 C C5  . PEX K 2 .   ? 170.254 110.129 145.825 1.00 79.06  ? 801 PEX D C5  1 
HETATM 19702 C C6  . PEX K 2 .   ? 170.715 108.847 146.553 1.00 81.19  ? 801 PEX D C6  1 
HETATM 19703 C C7  . PEX K 2 .   ? 172.094 109.070 147.213 1.00 87.88  ? 801 PEX D C7  1 
HETATM 19704 C C8  . PEX K 2 .   ? 172.646 107.797 147.887 1.00 83.85  ? 801 PEX D C8  1 
HETATM 19705 C C9  . PEX K 2 .   ? 173.868 108.066 148.804 1.00 83.16  ? 801 PEX D C9  1 
HETATM 19706 C C10 . PEX K 2 .   ? 175.093 108.664 148.071 1.00 85.80  ? 801 PEX D C10 1 
HETATM 19707 C C11 . PEX K 2 .   ? 176.335 108.736 148.989 1.00 81.32  ? 801 PEX D C11 1 
HETATM 19708 C C12 . PEX K 2 .   ? 177.561 109.402 148.324 1.00 82.64  ? 801 PEX D C12 1 
HETATM 19709 C C13 . PEX K 2 .   ? 177.451 110.935 148.246 1.00 82.39  ? 801 PEX D C13 1 
HETATM 19710 O O6  . PEX K 2 .   ? 167.439 113.390 147.340 1.00 88.06  ? 801 PEX D O6  1 
HETATM 19711 C C14 . PEX K 2 .   ? 167.103 112.777 148.510 1.00 84.92  ? 801 PEX D C14 1 
HETATM 19712 O O7  . PEX K 2 .   ? 166.077 112.153 148.676 1.00 89.60  ? 801 PEX D O7  1 
HETATM 19713 C C15 . PEX K 2 .   ? 168.128 112.971 149.609 1.00 73.04  ? 801 PEX D C15 1 
HETATM 19714 C C16 . PEX K 2 .   ? 169.143 111.801 149.646 1.00 81.03  ? 801 PEX D C16 1 
HETATM 19715 C C17 . PEX K 2 .   ? 169.462 111.335 151.080 1.00 83.77  ? 801 PEX D C17 1 
HETATM 19716 C C18 . PEX K 2 .   ? 168.368 110.415 151.681 1.00 86.09  ? 801 PEX D C18 1 
HETATM 19717 C C19 . PEX K 2 .   ? 168.499 108.945 151.221 1.00 83.67  ? 801 PEX D C19 1 
HETATM 19718 C C20 . PEX K 2 .   ? 167.388 108.045 151.800 1.00 79.32  ? 801 PEX D C20 1 
HETATM 19719 C C21 . PEX K 2 .   ? 167.523 106.591 151.290 1.00 82.84  ? 801 PEX D C21 1 
HETATM 19720 C C22 . PEX K 2 .   ? 166.281 105.733 151.611 1.00 84.52  ? 801 PEX D C22 1 
HETATM 19721 C C23 . PEX K 2 .   ? 166.297 104.382 150.872 1.00 77.04  ? 801 PEX D C23 1 
HETATM 19722 O O8  . PEX K 2 .   ? 165.364 115.977 142.617 1.00 85.45  ? 801 PEX D O8  1 
HETATM 19723 C C24 . PEX K 2 .   ? 165.755 117.170 143.321 1.00 76.11  ? 801 PEX D C24 1 
HETATM 19724 C C25 . PEX K 2 .   ? 164.887 118.339 142.785 1.00 71.32  ? 801 PEX D C25 1 
HETATM 19725 N N1  . PEX K 2 .   ? 165.309 118.887 141.421 1.00 71.11  ? 801 PEX D N1  1 
HETATM 19726 C C13 . RTO L 3 .   ? 165.743 155.327 101.815 1.00 104.69 ? 802 RTO D C13 1 
HETATM 19727 C C15 . RTO L 3 .   ? 166.539 157.592 101.575 1.00 99.68  ? 802 RTO D C15 1 
HETATM 19728 C C17 . RTO L 3 .   ? 164.224 157.013 100.860 1.00 104.59 ? 802 RTO D C17 1 
HETATM 19729 C C01 . RTO L 3 .   ? 170.337 152.512 106.345 1.00 97.78  ? 802 RTO D C01 1 
HETATM 19730 C C02 . RTO L 3 .   ? 169.248 153.547 106.600 1.00 97.39  ? 802 RTO D C02 1 
HETATM 19731 C C03 . RTO L 3 .   ? 168.638 153.959 105.270 1.00 97.16  ? 802 RTO D C03 1 
HETATM 19732 C C05 . RTO L 3 .   ? 169.082 156.383 105.614 1.00 100.60 ? 802 RTO D C05 1 
HETATM 19733 C C06 . RTO L 3 .   ? 170.400 156.836 106.224 1.00 99.83  ? 802 RTO D C06 1 
HETATM 19734 C C07 . RTO L 3 .   ? 170.100 158.007 107.152 1.00 100.59 ? 802 RTO D C07 1 
HETATM 19735 C C11 . RTO L 3 .   ? 167.948 155.902 102.499 1.00 103.62 ? 802 RTO D C11 1 
HETATM 19736 C C12 . RTO L 3 .   ? 166.956 154.963 102.343 1.00 102.64 ? 802 RTO D C12 1 
HETATM 19737 C C14 . RTO L 3 .   ? 165.528 156.644 101.427 1.00 104.45 ? 802 RTO D C14 1 
HETATM 19738 C C16 . RTO L 3 .   ? 167.750 157.212 102.108 1.00 101.15 ? 802 RTO D C16 1 
HETATM 19739 N N04 . RTO L 3 .   ? 169.277 155.186 104.804 1.00 102.62 ? 802 RTO D N04 1 
HETATM 19740 O O09 . RTO L 3 .   ? 169.611 154.063 102.659 1.00 108.09 ? 802 RTO D O09 1 
HETATM 19741 O O10 . RTO L 3 .   ? 170.432 156.382 102.954 1.00 105.69 ? 802 RTO D O10 1 
HETATM 19742 O O18 . RTO L 3 .   ? 163.346 156.180 100.784 1.00 102.85 ? 802 RTO D O18 1 
HETATM 19743 O O19 . RTO L 3 .   ? 164.011 158.266 100.426 1.00 103.44 ? 802 RTO D O19 1 
HETATM 19744 S S08 . RTO L 3 .   ? 169.472 155.365 103.173 1.00 113.98 ? 802 RTO D S08 1 
# 
