data_9B3U
# 
_entry.id   9B3U 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9B3U         pdb_00009b3u 10.2210/pdb9b3u/pdb 
WWPDB D_1000282647 ?            ?                   
EMDB  EMD-44156    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-02-26 ? 
2 'EM metadata'     1 0 2025-02-26 ? 
3 'Half map'        1 0 2025-02-26 1 
4 'Half map'        1 0 2025-02-26 2 
5 Image             1 0 2025-02-26 ? 
6 'Primary map'     1 0 2025-02-26 ? 
7 'Structure model' 1 1 2025-03-05 ? 
8 'EM metadata'     1 1 2025-03-05 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Half map'        repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 Image             repository 'Initial release' ? ? 
6 6 'Primary map'     repository 'Initial release' ? ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 7 'Structure model' 'Data collection'      
2 7 'Structure model' 'Database references'  
3 8 'EM metadata'     'Database references'  
4 8 'EM metadata'     'Experimental summary' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 7 'Structure model' citation        
2 7 'Structure model' citation_author 
3 7 'Structure model' em_admin        
4 8 'EM metadata'     citation        
5 8 'EM metadata'     citation_author 
6 8 'EM metadata'     em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  7 'Structure model' '_citation.country'                 
2  7 'Structure model' '_citation.journal_abbrev'          
3  7 'Structure model' '_citation.journal_id_CSD'          
4  7 'Structure model' '_citation.journal_id_ISSN'         
5  7 'Structure model' '_citation.pdbx_database_id_DOI'    
6  7 'Structure model' '_citation.pdbx_database_id_PubMed' 
7  7 'Structure model' '_citation.title'                   
8  7 'Structure model' '_citation.year'                    
9  7 'Structure model' '_citation_author.identifier_ORCID' 
10 7 'Structure model' '_citation_author.name'             
11 7 'Structure model' '_em_admin.last_update'             
12 8 'EM metadata'     '_citation.country'                 
13 8 'EM metadata'     '_citation.journal_abbrev'          
14 8 'EM metadata'     '_citation.journal_id_CSD'          
15 8 'EM metadata'     '_citation.journal_id_ISSN'         
16 8 'EM metadata'     '_citation.pdbx_database_id_DOI'    
17 8 'EM metadata'     '_citation.pdbx_database_id_PubMed' 
18 8 'EM metadata'     '_citation.title'                   
19 8 'EM metadata'     '_citation.year'                    
20 8 'EM metadata'     '_citation_author.identifier_ORCID' 
21 8 'EM metadata'     '_citation_author.name'             
22 8 'EM metadata'     '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9B3U 
_pdbx_database_status.recvd_initial_deposition_date   2024-03-20 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'rat TRPV2 WT bound to probenecid' 
_pdbx_database_related.db_id          EMD-44156 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              vmb@pennmedicine.upenn.edu 
_pdbx_contact_author.name_first         Vera 
_pdbx_contact_author.name_last          Moiseenkova-Bell 
_pdbx_contact_author.name_mi            Y 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-0589-4053 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Rocereta, J.A.'         1 0000-0002-3142-7846 
'Pumroy, R.A.'           2 0000-0002-6200-6083 
'Moiseenkova-Bell, V.Y.' 3 0000-0002-0589-4053 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Nat.Struct.Mol.Biol. 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           1545-9985 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Structural insights into TRPV2 modulation by probenecid.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41594-025-01494-9 
_citation.pdbx_database_id_PubMed   39972168 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Rocereta, J.A.'       1 ?                   
primary 'Sturhahn, T.'         2 ?                   
primary 'Pumroy, R.A.'         3 0000-0002-6200-6083 
primary 'Fricke, T.C.'         4 ?                   
primary 'Herzog, C.'           5 ?                   
primary 'Leffler, A.'          6 0000-0003-1121-6387 
primary 'Moiseenkova-Bell, V.' 7 0000-0002-0589-4053 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Transient receptor potential cation channel subfamily V member 2' 86798.891 4 ? ? ? ? 
2 non-polymer syn 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE                    522.632   4 ? ? ? ? 
3 non-polymer syn '4-(dipropylsulfamoyl)benzoic acid'                                285.359   4 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        
'TrpV2, Osm-9-like TRP channel 2, OTRPC2, Stretch-activated channel 2B, Vanilloid receptor-like protein 1, VRL-1' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MTSASSPPAFRLETSDGDEEGNAEVNKGKQEPPPMESPFQREDRNSSPQIKVNLNFIKRPPKNTSAPSQQEPDRFDRDRL
FSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDE
FYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLE
ATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFS
GPYQPLSRKFTEWCYGPVRVSLYDLSSVDSWEKNSVLEIIAFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNFACY
LVYMFIFTVVAYHQPSLDQPAIPSSKATFGESMLLLGHILILLGGIYLLLGQLWYFWRRRLFIWISFMDSYFEILFLLQA
LLTVLSQVLRFMETEWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSR
EARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNM
LIALMSETVNHVADNSWSIWKLQKAISVLEMENGYWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEEVNWAAWEKTLP
TLSEDPSGPGITGNKKNPTSKPGKNSASEEDHLPLQVLQSP
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MTSASSPPAFRLETSDGDEEGNAEVNKGKQEPPPMESPFQREDRNSSPQIKVNLNFIKRPPKNTSAPSQQEPDRFDRDRL
FSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDE
FYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLE
ATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFS
GPYQPLSRKFTEWCYGPVRVSLYDLSSVDSWEKNSVLEIIAFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNFACY
LVYMFIFTVVAYHQPSLDQPAIPSSKATFGESMLLLGHILILLGGIYLLLGQLWYFWRRRLFIWISFMDSYFEILFLLQA
LLTVLSQVLRFMETEWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSR
EARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNM
LIALMSETVNHVADNSWSIWKLQKAISVLEMENGYWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEEVNWAAWEKTLP
TLSEDPSGPGITGNKKNPTSKPGKNSASEEDHLPLQVLQSP
;
_entity_poly.pdbx_strand_id                 A,B,C,D 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE PEX 
3 '4-(dipropylsulfamoyl)benzoic acid'             RTO 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   THR n 
1 3   SER n 
1 4   ALA n 
1 5   SER n 
1 6   SER n 
1 7   PRO n 
1 8   PRO n 
1 9   ALA n 
1 10  PHE n 
1 11  ARG n 
1 12  LEU n 
1 13  GLU n 
1 14  THR n 
1 15  SER n 
1 16  ASP n 
1 17  GLY n 
1 18  ASP n 
1 19  GLU n 
1 20  GLU n 
1 21  GLY n 
1 22  ASN n 
1 23  ALA n 
1 24  GLU n 
1 25  VAL n 
1 26  ASN n 
1 27  LYS n 
1 28  GLY n 
1 29  LYS n 
1 30  GLN n 
1 31  GLU n 
1 32  PRO n 
1 33  PRO n 
1 34  PRO n 
1 35  MET n 
1 36  GLU n 
1 37  SER n 
1 38  PRO n 
1 39  PHE n 
1 40  GLN n 
1 41  ARG n 
1 42  GLU n 
1 43  ASP n 
1 44  ARG n 
1 45  ASN n 
1 46  SER n 
1 47  SER n 
1 48  PRO n 
1 49  GLN n 
1 50  ILE n 
1 51  LYS n 
1 52  VAL n 
1 53  ASN n 
1 54  LEU n 
1 55  ASN n 
1 56  PHE n 
1 57  ILE n 
1 58  LYS n 
1 59  ARG n 
1 60  PRO n 
1 61  PRO n 
1 62  LYS n 
1 63  ASN n 
1 64  THR n 
1 65  SER n 
1 66  ALA n 
1 67  PRO n 
1 68  SER n 
1 69  GLN n 
1 70  GLN n 
1 71  GLU n 
1 72  PRO n 
1 73  ASP n 
1 74  ARG n 
1 75  PHE n 
1 76  ASP n 
1 77  ARG n 
1 78  ASP n 
1 79  ARG n 
1 80  LEU n 
1 81  PHE n 
1 82  SER n 
1 83  VAL n 
1 84  VAL n 
1 85  SER n 
1 86  ARG n 
1 87  GLY n 
1 88  VAL n 
1 89  PRO n 
1 90  GLU n 
1 91  GLU n 
1 92  LEU n 
1 93  THR n 
1 94  GLY n 
1 95  LEU n 
1 96  LEU n 
1 97  GLU n 
1 98  TYR n 
1 99  LEU n 
1 100 ARG n 
1 101 TRP n 
1 102 ASN n 
1 103 SER n 
1 104 LYS n 
1 105 TYR n 
1 106 LEU n 
1 107 THR n 
1 108 ASP n 
1 109 SER n 
1 110 ALA n 
1 111 TYR n 
1 112 THR n 
1 113 GLU n 
1 114 GLY n 
1 115 SER n 
1 116 THR n 
1 117 GLY n 
1 118 LYS n 
1 119 THR n 
1 120 CYS n 
1 121 LEU n 
1 122 MET n 
1 123 LYS n 
1 124 ALA n 
1 125 VAL n 
1 126 LEU n 
1 127 ASN n 
1 128 LEU n 
1 129 GLN n 
1 130 ASP n 
1 131 GLY n 
1 132 VAL n 
1 133 ASN n 
1 134 ALA n 
1 135 CYS n 
1 136 ILE n 
1 137 MET n 
1 138 PRO n 
1 139 LEU n 
1 140 LEU n 
1 141 GLN n 
1 142 ILE n 
1 143 ASP n 
1 144 LYS n 
1 145 ASP n 
1 146 SER n 
1 147 GLY n 
1 148 ASN n 
1 149 PRO n 
1 150 LYS n 
1 151 LEU n 
1 152 LEU n 
1 153 VAL n 
1 154 ASN n 
1 155 ALA n 
1 156 GLN n 
1 157 CYS n 
1 158 THR n 
1 159 ASP n 
1 160 GLU n 
1 161 PHE n 
1 162 TYR n 
1 163 GLN n 
1 164 GLY n 
1 165 HIS n 
1 166 SER n 
1 167 ALA n 
1 168 LEU n 
1 169 HIS n 
1 170 ILE n 
1 171 ALA n 
1 172 ILE n 
1 173 GLU n 
1 174 LYS n 
1 175 ARG n 
1 176 SER n 
1 177 LEU n 
1 178 GLN n 
1 179 CYS n 
1 180 VAL n 
1 181 LYS n 
1 182 LEU n 
1 183 LEU n 
1 184 VAL n 
1 185 GLU n 
1 186 ASN n 
1 187 GLY n 
1 188 ALA n 
1 189 ASP n 
1 190 VAL n 
1 191 HIS n 
1 192 LEU n 
1 193 ARG n 
1 194 ALA n 
1 195 CYS n 
1 196 GLY n 
1 197 ARG n 
1 198 PHE n 
1 199 PHE n 
1 200 GLN n 
1 201 LYS n 
1 202 HIS n 
1 203 GLN n 
1 204 GLY n 
1 205 THR n 
1 206 CYS n 
1 207 PHE n 
1 208 TYR n 
1 209 PHE n 
1 210 GLY n 
1 211 GLU n 
1 212 LEU n 
1 213 PRO n 
1 214 LEU n 
1 215 SER n 
1 216 LEU n 
1 217 ALA n 
1 218 ALA n 
1 219 CYS n 
1 220 THR n 
1 221 LYS n 
1 222 GLN n 
1 223 TRP n 
1 224 ASP n 
1 225 VAL n 
1 226 VAL n 
1 227 THR n 
1 228 TYR n 
1 229 LEU n 
1 230 LEU n 
1 231 GLU n 
1 232 ASN n 
1 233 PRO n 
1 234 HIS n 
1 235 GLN n 
1 236 PRO n 
1 237 ALA n 
1 238 SER n 
1 239 LEU n 
1 240 GLU n 
1 241 ALA n 
1 242 THR n 
1 243 ASP n 
1 244 SER n 
1 245 LEU n 
1 246 GLY n 
1 247 ASN n 
1 248 THR n 
1 249 VAL n 
1 250 LEU n 
1 251 HIS n 
1 252 ALA n 
1 253 LEU n 
1 254 VAL n 
1 255 MET n 
1 256 ILE n 
1 257 ALA n 
1 258 ASP n 
1 259 ASN n 
1 260 SER n 
1 261 PRO n 
1 262 GLU n 
1 263 ASN n 
1 264 SER n 
1 265 ALA n 
1 266 LEU n 
1 267 VAL n 
1 268 ILE n 
1 269 HIS n 
1 270 MET n 
1 271 TYR n 
1 272 ASP n 
1 273 GLY n 
1 274 LEU n 
1 275 LEU n 
1 276 GLN n 
1 277 MET n 
1 278 GLY n 
1 279 ALA n 
1 280 ARG n 
1 281 LEU n 
1 282 CYS n 
1 283 PRO n 
1 284 THR n 
1 285 VAL n 
1 286 GLN n 
1 287 LEU n 
1 288 GLU n 
1 289 GLU n 
1 290 ILE n 
1 291 SER n 
1 292 ASN n 
1 293 HIS n 
1 294 GLN n 
1 295 GLY n 
1 296 LEU n 
1 297 THR n 
1 298 PRO n 
1 299 LEU n 
1 300 LYS n 
1 301 LEU n 
1 302 ALA n 
1 303 ALA n 
1 304 LYS n 
1 305 GLU n 
1 306 GLY n 
1 307 LYS n 
1 308 ILE n 
1 309 GLU n 
1 310 ILE n 
1 311 PHE n 
1 312 ARG n 
1 313 HIS n 
1 314 ILE n 
1 315 LEU n 
1 316 GLN n 
1 317 ARG n 
1 318 GLU n 
1 319 PHE n 
1 320 SER n 
1 321 GLY n 
1 322 PRO n 
1 323 TYR n 
1 324 GLN n 
1 325 PRO n 
1 326 LEU n 
1 327 SER n 
1 328 ARG n 
1 329 LYS n 
1 330 PHE n 
1 331 THR n 
1 332 GLU n 
1 333 TRP n 
1 334 CYS n 
1 335 TYR n 
1 336 GLY n 
1 337 PRO n 
1 338 VAL n 
1 339 ARG n 
1 340 VAL n 
1 341 SER n 
1 342 LEU n 
1 343 TYR n 
1 344 ASP n 
1 345 LEU n 
1 346 SER n 
1 347 SER n 
1 348 VAL n 
1 349 ASP n 
1 350 SER n 
1 351 TRP n 
1 352 GLU n 
1 353 LYS n 
1 354 ASN n 
1 355 SER n 
1 356 VAL n 
1 357 LEU n 
1 358 GLU n 
1 359 ILE n 
1 360 ILE n 
1 361 ALA n 
1 362 PHE n 
1 363 HIS n 
1 364 CYS n 
1 365 LYS n 
1 366 SER n 
1 367 PRO n 
1 368 ASN n 
1 369 ARG n 
1 370 HIS n 
1 371 ARG n 
1 372 MET n 
1 373 VAL n 
1 374 VAL n 
1 375 LEU n 
1 376 GLU n 
1 377 PRO n 
1 378 LEU n 
1 379 ASN n 
1 380 LYS n 
1 381 LEU n 
1 382 LEU n 
1 383 GLN n 
1 384 GLU n 
1 385 LYS n 
1 386 TRP n 
1 387 ASP n 
1 388 ARG n 
1 389 LEU n 
1 390 VAL n 
1 391 SER n 
1 392 ARG n 
1 393 PHE n 
1 394 PHE n 
1 395 PHE n 
1 396 ASN n 
1 397 PHE n 
1 398 ALA n 
1 399 CYS n 
1 400 TYR n 
1 401 LEU n 
1 402 VAL n 
1 403 TYR n 
1 404 MET n 
1 405 PHE n 
1 406 ILE n 
1 407 PHE n 
1 408 THR n 
1 409 VAL n 
1 410 VAL n 
1 411 ALA n 
1 412 TYR n 
1 413 HIS n 
1 414 GLN n 
1 415 PRO n 
1 416 SER n 
1 417 LEU n 
1 418 ASP n 
1 419 GLN n 
1 420 PRO n 
1 421 ALA n 
1 422 ILE n 
1 423 PRO n 
1 424 SER n 
1 425 SER n 
1 426 LYS n 
1 427 ALA n 
1 428 THR n 
1 429 PHE n 
1 430 GLY n 
1 431 GLU n 
1 432 SER n 
1 433 MET n 
1 434 LEU n 
1 435 LEU n 
1 436 LEU n 
1 437 GLY n 
1 438 HIS n 
1 439 ILE n 
1 440 LEU n 
1 441 ILE n 
1 442 LEU n 
1 443 LEU n 
1 444 GLY n 
1 445 GLY n 
1 446 ILE n 
1 447 TYR n 
1 448 LEU n 
1 449 LEU n 
1 450 LEU n 
1 451 GLY n 
1 452 GLN n 
1 453 LEU n 
1 454 TRP n 
1 455 TYR n 
1 456 PHE n 
1 457 TRP n 
1 458 ARG n 
1 459 ARG n 
1 460 ARG n 
1 461 LEU n 
1 462 PHE n 
1 463 ILE n 
1 464 TRP n 
1 465 ILE n 
1 466 SER n 
1 467 PHE n 
1 468 MET n 
1 469 ASP n 
1 470 SER n 
1 471 TYR n 
1 472 PHE n 
1 473 GLU n 
1 474 ILE n 
1 475 LEU n 
1 476 PHE n 
1 477 LEU n 
1 478 LEU n 
1 479 GLN n 
1 480 ALA n 
1 481 LEU n 
1 482 LEU n 
1 483 THR n 
1 484 VAL n 
1 485 LEU n 
1 486 SER n 
1 487 GLN n 
1 488 VAL n 
1 489 LEU n 
1 490 ARG n 
1 491 PHE n 
1 492 MET n 
1 493 GLU n 
1 494 THR n 
1 495 GLU n 
1 496 TRP n 
1 497 TYR n 
1 498 LEU n 
1 499 PRO n 
1 500 LEU n 
1 501 LEU n 
1 502 VAL n 
1 503 LEU n 
1 504 SER n 
1 505 LEU n 
1 506 VAL n 
1 507 LEU n 
1 508 GLY n 
1 509 TRP n 
1 510 LEU n 
1 511 ASN n 
1 512 LEU n 
1 513 LEU n 
1 514 TYR n 
1 515 TYR n 
1 516 THR n 
1 517 ARG n 
1 518 GLY n 
1 519 PHE n 
1 520 GLN n 
1 521 HIS n 
1 522 THR n 
1 523 GLY n 
1 524 ILE n 
1 525 TYR n 
1 526 SER n 
1 527 VAL n 
1 528 MET n 
1 529 ILE n 
1 530 GLN n 
1 531 LYS n 
1 532 VAL n 
1 533 ILE n 
1 534 LEU n 
1 535 ARG n 
1 536 ASP n 
1 537 LEU n 
1 538 LEU n 
1 539 ARG n 
1 540 PHE n 
1 541 LEU n 
1 542 LEU n 
1 543 VAL n 
1 544 TYR n 
1 545 LEU n 
1 546 VAL n 
1 547 PHE n 
1 548 LEU n 
1 549 PHE n 
1 550 GLY n 
1 551 PHE n 
1 552 ALA n 
1 553 VAL n 
1 554 ALA n 
1 555 LEU n 
1 556 VAL n 
1 557 SER n 
1 558 LEU n 
1 559 SER n 
1 560 ARG n 
1 561 GLU n 
1 562 ALA n 
1 563 ARG n 
1 564 SER n 
1 565 PRO n 
1 566 LYS n 
1 567 ALA n 
1 568 PRO n 
1 569 GLU n 
1 570 ASP n 
1 571 ASN n 
1 572 ASN n 
1 573 SER n 
1 574 THR n 
1 575 VAL n 
1 576 THR n 
1 577 GLU n 
1 578 GLN n 
1 579 PRO n 
1 580 THR n 
1 581 VAL n 
1 582 GLY n 
1 583 GLN n 
1 584 GLU n 
1 585 GLU n 
1 586 GLU n 
1 587 PRO n 
1 588 ALA n 
1 589 PRO n 
1 590 TYR n 
1 591 ARG n 
1 592 SER n 
1 593 ILE n 
1 594 LEU n 
1 595 ASP n 
1 596 ALA n 
1 597 SER n 
1 598 LEU n 
1 599 GLU n 
1 600 LEU n 
1 601 PHE n 
1 602 LYS n 
1 603 PHE n 
1 604 THR n 
1 605 ILE n 
1 606 GLY n 
1 607 MET n 
1 608 GLY n 
1 609 GLU n 
1 610 LEU n 
1 611 ALA n 
1 612 PHE n 
1 613 GLN n 
1 614 GLU n 
1 615 GLN n 
1 616 LEU n 
1 617 ARG n 
1 618 PHE n 
1 619 ARG n 
1 620 GLY n 
1 621 VAL n 
1 622 VAL n 
1 623 LEU n 
1 624 LEU n 
1 625 LEU n 
1 626 LEU n 
1 627 LEU n 
1 628 ALA n 
1 629 TYR n 
1 630 VAL n 
1 631 LEU n 
1 632 LEU n 
1 633 THR n 
1 634 TYR n 
1 635 VAL n 
1 636 LEU n 
1 637 LEU n 
1 638 LEU n 
1 639 ASN n 
1 640 MET n 
1 641 LEU n 
1 642 ILE n 
1 643 ALA n 
1 644 LEU n 
1 645 MET n 
1 646 SER n 
1 647 GLU n 
1 648 THR n 
1 649 VAL n 
1 650 ASN n 
1 651 HIS n 
1 652 VAL n 
1 653 ALA n 
1 654 ASP n 
1 655 ASN n 
1 656 SER n 
1 657 TRP n 
1 658 SER n 
1 659 ILE n 
1 660 TRP n 
1 661 LYS n 
1 662 LEU n 
1 663 GLN n 
1 664 LYS n 
1 665 ALA n 
1 666 ILE n 
1 667 SER n 
1 668 VAL n 
1 669 LEU n 
1 670 GLU n 
1 671 MET n 
1 672 GLU n 
1 673 ASN n 
1 674 GLY n 
1 675 TYR n 
1 676 TRP n 
1 677 TRP n 
1 678 CYS n 
1 679 ARG n 
1 680 ARG n 
1 681 LYS n 
1 682 LYS n 
1 683 HIS n 
1 684 ARG n 
1 685 GLU n 
1 686 GLY n 
1 687 ARG n 
1 688 LEU n 
1 689 LEU n 
1 690 LYS n 
1 691 VAL n 
1 692 GLY n 
1 693 THR n 
1 694 ARG n 
1 695 GLY n 
1 696 ASP n 
1 697 GLY n 
1 698 THR n 
1 699 PRO n 
1 700 ASP n 
1 701 GLU n 
1 702 ARG n 
1 703 TRP n 
1 704 CYS n 
1 705 PHE n 
1 706 ARG n 
1 707 VAL n 
1 708 GLU n 
1 709 GLU n 
1 710 VAL n 
1 711 ASN n 
1 712 TRP n 
1 713 ALA n 
1 714 ALA n 
1 715 TRP n 
1 716 GLU n 
1 717 LYS n 
1 718 THR n 
1 719 LEU n 
1 720 PRO n 
1 721 THR n 
1 722 LEU n 
1 723 SER n 
1 724 GLU n 
1 725 ASP n 
1 726 PRO n 
1 727 SER n 
1 728 GLY n 
1 729 PRO n 
1 730 GLY n 
1 731 ILE n 
1 732 THR n 
1 733 GLY n 
1 734 ASN n 
1 735 LYS n 
1 736 LYS n 
1 737 ASN n 
1 738 PRO n 
1 739 THR n 
1 740 SER n 
1 741 LYS n 
1 742 PRO n 
1 743 GLY n 
1 744 LYS n 
1 745 ASN n 
1 746 SER n 
1 747 ALA n 
1 748 SER n 
1 749 GLU n 
1 750 GLU n 
1 751 ASP n 
1 752 HIS n 
1 753 LEU n 
1 754 PRO n 
1 755 LEU n 
1 756 GLN n 
1 757 VAL n 
1 758 LEU n 
1 759 GLN n 
1 760 SER n 
1 761 PRO n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   761 
_entity_src_gen.gene_src_common_name               'Norway rat' 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'Trpv2, Sac2b, Vrl1' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Rattus norvegicus' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     10116 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Saccharomyces cerevisiae' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     4932 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                         ? 'C3 H7 N O2'        89.093  
ARG 'L-peptide linking' y ARGININE                                        ? 'C6 H15 N4 O2 1'    175.209 
ASN 'L-peptide linking' y ASPARAGINE                                      ? 'C4 H8 N2 O3'       132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                                 ? 'C4 H7 N O4'        133.103 
CYS 'L-peptide linking' y CYSTEINE                                        ? 'C3 H7 N O2 S'      121.158 
GLN 'L-peptide linking' y GLUTAMINE                                       ? 'C5 H10 N2 O3'      146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                                 ? 'C5 H9 N O4'        147.129 
GLY 'peptide linking'   y GLYCINE                                         ? 'C2 H5 N O2'        75.067  
HIS 'L-peptide linking' y HISTIDINE                                       ? 'C6 H10 N3 O2 1'    156.162 
ILE 'L-peptide linking' y ISOLEUCINE                                      ? 'C6 H13 N O2'       131.173 
LEU 'L-peptide linking' y LEUCINE                                         ? 'C6 H13 N O2'       131.173 
LYS 'L-peptide linking' y LYSINE                                          ? 'C6 H15 N2 O2 1'    147.195 
MET 'L-peptide linking' y METHIONINE                                      ? 'C5 H11 N O2 S'     149.211 
PEX non-polymer         . 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE ? 'C25 H49 N O8 P -1' 522.632 
PHE 'L-peptide linking' y PHENYLALANINE                                   ? 'C9 H11 N O2'       165.189 
PRO 'L-peptide linking' y PROLINE                                         ? 'C5 H9 N O2'        115.130 
RTO non-polymer         . '4-(dipropylsulfamoyl)benzoic acid'             ? 'C13 H19 N O4 S'    285.359 
SER 'L-peptide linking' y SERINE                                          ? 'C3 H7 N O3'        105.093 
THR 'L-peptide linking' y THREONINE                                       ? 'C4 H9 N O3'        119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                      ? 'C11 H12 N2 O2'     204.225 
TYR 'L-peptide linking' y TYROSINE                                        ? 'C9 H11 N O3'       181.189 
VAL 'L-peptide linking' y VALINE                                          ? 'C5 H11 N O2'       117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   THR 2   2   ?   ?   ?   A . n 
A 1 3   SER 3   3   ?   ?   ?   A . n 
A 1 4   ALA 4   4   ?   ?   ?   A . n 
A 1 5   SER 5   5   ?   ?   ?   A . n 
A 1 6   SER 6   6   ?   ?   ?   A . n 
A 1 7   PRO 7   7   ?   ?   ?   A . n 
A 1 8   PRO 8   8   ?   ?   ?   A . n 
A 1 9   ALA 9   9   ?   ?   ?   A . n 
A 1 10  PHE 10  10  ?   ?   ?   A . n 
A 1 11  ARG 11  11  ?   ?   ?   A . n 
A 1 12  LEU 12  12  ?   ?   ?   A . n 
A 1 13  GLU 13  13  ?   ?   ?   A . n 
A 1 14  THR 14  14  ?   ?   ?   A . n 
A 1 15  SER 15  15  ?   ?   ?   A . n 
A 1 16  ASP 16  16  ?   ?   ?   A . n 
A 1 17  GLY 17  17  ?   ?   ?   A . n 
A 1 18  ASP 18  18  ?   ?   ?   A . n 
A 1 19  GLU 19  19  ?   ?   ?   A . n 
A 1 20  GLU 20  20  ?   ?   ?   A . n 
A 1 21  GLY 21  21  ?   ?   ?   A . n 
A 1 22  ASN 22  22  ?   ?   ?   A . n 
A 1 23  ALA 23  23  ?   ?   ?   A . n 
A 1 24  GLU 24  24  ?   ?   ?   A . n 
A 1 25  VAL 25  25  ?   ?   ?   A . n 
A 1 26  ASN 26  26  ?   ?   ?   A . n 
A 1 27  LYS 27  27  ?   ?   ?   A . n 
A 1 28  GLY 28  28  ?   ?   ?   A . n 
A 1 29  LYS 29  29  ?   ?   ?   A . n 
A 1 30  GLN 30  30  ?   ?   ?   A . n 
A 1 31  GLU 31  31  ?   ?   ?   A . n 
A 1 32  PRO 32  32  ?   ?   ?   A . n 
A 1 33  PRO 33  33  ?   ?   ?   A . n 
A 1 34  PRO 34  34  ?   ?   ?   A . n 
A 1 35  MET 35  35  ?   ?   ?   A . n 
A 1 36  GLU 36  36  ?   ?   ?   A . n 
A 1 37  SER 37  37  ?   ?   ?   A . n 
A 1 38  PRO 38  38  ?   ?   ?   A . n 
A 1 39  PHE 39  39  ?   ?   ?   A . n 
A 1 40  GLN 40  40  ?   ?   ?   A . n 
A 1 41  ARG 41  41  ?   ?   ?   A . n 
A 1 42  GLU 42  42  ?   ?   ?   A . n 
A 1 43  ASP 43  43  ?   ?   ?   A . n 
A 1 44  ARG 44  44  ?   ?   ?   A . n 
A 1 45  ASN 45  45  ?   ?   ?   A . n 
A 1 46  SER 46  46  ?   ?   ?   A . n 
A 1 47  SER 47  47  ?   ?   ?   A . n 
A 1 48  PRO 48  48  ?   ?   ?   A . n 
A 1 49  GLN 49  49  ?   ?   ?   A . n 
A 1 50  ILE 50  50  ?   ?   ?   A . n 
A 1 51  LYS 51  51  ?   ?   ?   A . n 
A 1 52  VAL 52  52  ?   ?   ?   A . n 
A 1 53  ASN 53  53  ?   ?   ?   A . n 
A 1 54  LEU 54  54  ?   ?   ?   A . n 
A 1 55  ASN 55  55  ?   ?   ?   A . n 
A 1 56  PHE 56  56  ?   ?   ?   A . n 
A 1 57  ILE 57  57  ?   ?   ?   A . n 
A 1 58  LYS 58  58  ?   ?   ?   A . n 
A 1 59  ARG 59  59  ?   ?   ?   A . n 
A 1 60  PRO 60  60  ?   ?   ?   A . n 
A 1 61  PRO 61  61  ?   ?   ?   A . n 
A 1 62  LYS 62  62  ?   ?   ?   A . n 
A 1 63  ASN 63  63  ?   ?   ?   A . n 
A 1 64  THR 64  64  ?   ?   ?   A . n 
A 1 65  SER 65  65  ?   ?   ?   A . n 
A 1 66  ALA 66  66  ?   ?   ?   A . n 
A 1 67  PRO 67  67  ?   ?   ?   A . n 
A 1 68  SER 68  68  ?   ?   ?   A . n 
A 1 69  GLN 69  69  ?   ?   ?   A . n 
A 1 70  GLN 70  70  ?   ?   ?   A . n 
A 1 71  GLU 71  71  ?   ?   ?   A . n 
A 1 72  PRO 72  72  ?   ?   ?   A . n 
A 1 73  ASP 73  73  ?   ?   ?   A . n 
A 1 74  ARG 74  74  74  ARG ARG A . n 
A 1 75  PHE 75  75  75  PHE PHE A . n 
A 1 76  ASP 76  76  76  ASP ASP A . n 
A 1 77  ARG 77  77  77  ARG ARG A . n 
A 1 78  ASP 78  78  78  ASP ASP A . n 
A 1 79  ARG 79  79  79  ARG ARG A . n 
A 1 80  LEU 80  80  80  LEU LEU A . n 
A 1 81  PHE 81  81  81  PHE PHE A . n 
A 1 82  SER 82  82  82  SER SER A . n 
A 1 83  VAL 83  83  83  VAL VAL A . n 
A 1 84  VAL 84  84  84  VAL VAL A . n 
A 1 85  SER 85  85  85  SER SER A . n 
A 1 86  ARG 86  86  86  ARG ARG A . n 
A 1 87  GLY 87  87  87  GLY GLY A . n 
A 1 88  VAL 88  88  88  VAL VAL A . n 
A 1 89  PRO 89  89  89  PRO PRO A . n 
A 1 90  GLU 90  90  90  GLU GLU A . n 
A 1 91  GLU 91  91  91  GLU GLU A . n 
A 1 92  LEU 92  92  92  LEU LEU A . n 
A 1 93  THR 93  93  93  THR THR A . n 
A 1 94  GLY 94  94  94  GLY GLY A . n 
A 1 95  LEU 95  95  95  LEU LEU A . n 
A 1 96  LEU 96  96  96  LEU LEU A . n 
A 1 97  GLU 97  97  97  GLU GLU A . n 
A 1 98  TYR 98  98  98  TYR TYR A . n 
A 1 99  LEU 99  99  99  LEU LEU A . n 
A 1 100 ARG 100 100 100 ARG ARG A . n 
A 1 101 TRP 101 101 101 TRP TRP A . n 
A 1 102 ASN 102 102 102 ASN ASN A . n 
A 1 103 SER 103 103 103 SER SER A . n 
A 1 104 LYS 104 104 104 LYS LYS A . n 
A 1 105 TYR 105 105 105 TYR TYR A . n 
A 1 106 LEU 106 106 106 LEU LEU A . n 
A 1 107 THR 107 107 107 THR THR A . n 
A 1 108 ASP 108 108 108 ASP ASP A . n 
A 1 109 SER 109 109 109 SER SER A . n 
A 1 110 ALA 110 110 110 ALA ALA A . n 
A 1 111 TYR 111 111 111 TYR TYR A . n 
A 1 112 THR 112 112 112 THR THR A . n 
A 1 113 GLU 113 113 113 GLU GLU A . n 
A 1 114 GLY 114 114 114 GLY GLY A . n 
A 1 115 SER 115 115 115 SER SER A . n 
A 1 116 THR 116 116 116 THR THR A . n 
A 1 117 GLY 117 117 117 GLY GLY A . n 
A 1 118 LYS 118 118 118 LYS LYS A . n 
A 1 119 THR 119 119 119 THR THR A . n 
A 1 120 CYS 120 120 120 CYS CYS A . n 
A 1 121 LEU 121 121 121 LEU LEU A . n 
A 1 122 MET 122 122 122 MET MET A . n 
A 1 123 LYS 123 123 123 LYS LYS A . n 
A 1 124 ALA 124 124 124 ALA ALA A . n 
A 1 125 VAL 125 125 125 VAL VAL A . n 
A 1 126 LEU 126 126 126 LEU LEU A . n 
A 1 127 ASN 127 127 127 ASN ASN A . n 
A 1 128 LEU 128 128 128 LEU LEU A . n 
A 1 129 GLN 129 129 129 GLN GLN A . n 
A 1 130 ASP 130 130 130 ASP ASP A . n 
A 1 131 GLY 131 131 131 GLY GLY A . n 
A 1 132 VAL 132 132 132 VAL VAL A . n 
A 1 133 ASN 133 133 133 ASN ASN A . n 
A 1 134 ALA 134 134 134 ALA ALA A . n 
A 1 135 CYS 135 135 135 CYS CYS A . n 
A 1 136 ILE 136 136 136 ILE ILE A . n 
A 1 137 MET 137 137 137 MET MET A . n 
A 1 138 PRO 138 138 138 PRO PRO A . n 
A 1 139 LEU 139 139 139 LEU LEU A . n 
A 1 140 LEU 140 140 140 LEU LEU A . n 
A 1 141 GLN 141 141 141 GLN GLN A . n 
A 1 142 ILE 142 142 142 ILE ILE A . n 
A 1 143 ASP 143 143 143 ASP ASP A . n 
A 1 144 LYS 144 144 144 LYS LYS A . n 
A 1 145 ASP 145 145 145 ASP ASP A . n 
A 1 146 SER 146 146 146 SER SER A . n 
A 1 147 GLY 147 147 147 GLY GLY A . n 
A 1 148 ASN 148 148 148 ASN ASN A . n 
A 1 149 PRO 149 149 149 PRO PRO A . n 
A 1 150 LYS 150 150 150 LYS LYS A . n 
A 1 151 LEU 151 151 151 LEU LEU A . n 
A 1 152 LEU 152 152 152 LEU LEU A . n 
A 1 153 VAL 153 153 153 VAL VAL A . n 
A 1 154 ASN 154 154 154 ASN ASN A . n 
A 1 155 ALA 155 155 155 ALA ALA A . n 
A 1 156 GLN 156 156 156 GLN GLN A . n 
A 1 157 CYS 157 157 157 CYS CYS A . n 
A 1 158 THR 158 158 158 THR THR A . n 
A 1 159 ASP 159 159 159 ASP ASP A . n 
A 1 160 GLU 160 160 160 GLU GLU A . n 
A 1 161 PHE 161 161 161 PHE PHE A . n 
A 1 162 TYR 162 162 162 TYR TYR A . n 
A 1 163 GLN 163 163 163 GLN GLN A . n 
A 1 164 GLY 164 164 164 GLY GLY A . n 
A 1 165 HIS 165 165 165 HIS HIS A . n 
A 1 166 SER 166 166 166 SER SER A . n 
A 1 167 ALA 167 167 167 ALA ALA A . n 
A 1 168 LEU 168 168 168 LEU LEU A . n 
A 1 169 HIS 169 169 169 HIS HIS A . n 
A 1 170 ILE 170 170 170 ILE ILE A . n 
A 1 171 ALA 171 171 171 ALA ALA A . n 
A 1 172 ILE 172 172 172 ILE ILE A . n 
A 1 173 GLU 173 173 173 GLU GLU A . n 
A 1 174 LYS 174 174 174 LYS LYS A . n 
A 1 175 ARG 175 175 175 ARG ARG A . n 
A 1 176 SER 176 176 176 SER SER A . n 
A 1 177 LEU 177 177 177 LEU LEU A . n 
A 1 178 GLN 178 178 178 GLN GLN A . n 
A 1 179 CYS 179 179 179 CYS CYS A . n 
A 1 180 VAL 180 180 180 VAL VAL A . n 
A 1 181 LYS 181 181 181 LYS LYS A . n 
A 1 182 LEU 182 182 182 LEU LEU A . n 
A 1 183 LEU 183 183 183 LEU LEU A . n 
A 1 184 VAL 184 184 184 VAL VAL A . n 
A 1 185 GLU 185 185 185 GLU GLU A . n 
A 1 186 ASN 186 186 186 ASN ASN A . n 
A 1 187 GLY 187 187 187 GLY GLY A . n 
A 1 188 ALA 188 188 188 ALA ALA A . n 
A 1 189 ASP 189 189 189 ASP ASP A . n 
A 1 190 VAL 190 190 190 VAL VAL A . n 
A 1 191 HIS 191 191 191 HIS HIS A . n 
A 1 192 LEU 192 192 192 LEU LEU A . n 
A 1 193 ARG 193 193 193 ARG ARG A . n 
A 1 194 ALA 194 194 194 ALA ALA A . n 
A 1 195 CYS 195 195 195 CYS CYS A . n 
A 1 196 GLY 196 196 196 GLY GLY A . n 
A 1 197 ARG 197 197 197 ARG ARG A . n 
A 1 198 PHE 198 198 198 PHE PHE A . n 
A 1 199 PHE 199 199 199 PHE PHE A . n 
A 1 200 GLN 200 200 200 GLN GLN A . n 
A 1 201 LYS 201 201 201 LYS LYS A . n 
A 1 202 HIS 202 202 202 HIS HIS A . n 
A 1 203 GLN 203 203 203 GLN GLN A . n 
A 1 204 GLY 204 204 204 GLY GLY A . n 
A 1 205 THR 205 205 205 THR THR A . n 
A 1 206 CYS 206 206 206 CYS CYS A . n 
A 1 207 PHE 207 207 207 PHE PHE A . n 
A 1 208 TYR 208 208 208 TYR TYR A . n 
A 1 209 PHE 209 209 209 PHE PHE A . n 
A 1 210 GLY 210 210 210 GLY GLY A . n 
A 1 211 GLU 211 211 211 GLU GLU A . n 
A 1 212 LEU 212 212 212 LEU LEU A . n 
A 1 213 PRO 213 213 213 PRO PRO A . n 
A 1 214 LEU 214 214 214 LEU LEU A . n 
A 1 215 SER 215 215 215 SER SER A . n 
A 1 216 LEU 216 216 216 LEU LEU A . n 
A 1 217 ALA 217 217 217 ALA ALA A . n 
A 1 218 ALA 218 218 218 ALA ALA A . n 
A 1 219 CYS 219 219 219 CYS CYS A . n 
A 1 220 THR 220 220 220 THR THR A . n 
A 1 221 LYS 221 221 221 LYS LYS A . n 
A 1 222 GLN 222 222 222 GLN GLN A . n 
A 1 223 TRP 223 223 223 TRP TRP A . n 
A 1 224 ASP 224 224 224 ASP ASP A . n 
A 1 225 VAL 225 225 225 VAL VAL A . n 
A 1 226 VAL 226 226 226 VAL VAL A . n 
A 1 227 THR 227 227 227 THR THR A . n 
A 1 228 TYR 228 228 228 TYR TYR A . n 
A 1 229 LEU 229 229 229 LEU LEU A . n 
A 1 230 LEU 230 230 230 LEU LEU A . n 
A 1 231 GLU 231 231 231 GLU GLU A . n 
A 1 232 ASN 232 232 232 ASN ASN A . n 
A 1 233 PRO 233 233 233 PRO PRO A . n 
A 1 234 HIS 234 234 234 HIS HIS A . n 
A 1 235 GLN 235 235 235 GLN GLN A . n 
A 1 236 PRO 236 236 236 PRO PRO A . n 
A 1 237 ALA 237 237 237 ALA ALA A . n 
A 1 238 SER 238 238 238 SER SER A . n 
A 1 239 LEU 239 239 239 LEU LEU A . n 
A 1 240 GLU 240 240 240 GLU GLU A . n 
A 1 241 ALA 241 241 241 ALA ALA A . n 
A 1 242 THR 242 242 242 THR THR A . n 
A 1 243 ASP 243 243 243 ASP ASP A . n 
A 1 244 SER 244 244 244 SER SER A . n 
A 1 245 LEU 245 245 245 LEU LEU A . n 
A 1 246 GLY 246 246 246 GLY GLY A . n 
A 1 247 ASN 247 247 247 ASN ASN A . n 
A 1 248 THR 248 248 248 THR THR A . n 
A 1 249 VAL 249 249 249 VAL VAL A . n 
A 1 250 LEU 250 250 250 LEU LEU A . n 
A 1 251 HIS 251 251 251 HIS HIS A . n 
A 1 252 ALA 252 252 252 ALA ALA A . n 
A 1 253 LEU 253 253 253 LEU LEU A . n 
A 1 254 VAL 254 254 254 VAL VAL A . n 
A 1 255 MET 255 255 255 MET MET A . n 
A 1 256 ILE 256 256 256 ILE ILE A . n 
A 1 257 ALA 257 257 257 ALA ALA A . n 
A 1 258 ASP 258 258 258 ASP ASP A . n 
A 1 259 ASN 259 259 259 ASN ASN A . n 
A 1 260 SER 260 260 260 SER SER A . n 
A 1 261 PRO 261 261 261 PRO PRO A . n 
A 1 262 GLU 262 262 262 GLU GLU A . n 
A 1 263 ASN 263 263 263 ASN ASN A . n 
A 1 264 SER 264 264 264 SER SER A . n 
A 1 265 ALA 265 265 265 ALA ALA A . n 
A 1 266 LEU 266 266 266 LEU LEU A . n 
A 1 267 VAL 267 267 267 VAL VAL A . n 
A 1 268 ILE 268 268 268 ILE ILE A . n 
A 1 269 HIS 269 269 269 HIS HIS A . n 
A 1 270 MET 270 270 270 MET MET A . n 
A 1 271 TYR 271 271 271 TYR TYR A . n 
A 1 272 ASP 272 272 272 ASP ASP A . n 
A 1 273 GLY 273 273 273 GLY GLY A . n 
A 1 274 LEU 274 274 274 LEU LEU A . n 
A 1 275 LEU 275 275 275 LEU LEU A . n 
A 1 276 GLN 276 276 276 GLN GLN A . n 
A 1 277 MET 277 277 277 MET MET A . n 
A 1 278 GLY 278 278 278 GLY GLY A . n 
A 1 279 ALA 279 279 279 ALA ALA A . n 
A 1 280 ARG 280 280 280 ARG ARG A . n 
A 1 281 LEU 281 281 281 LEU LEU A . n 
A 1 282 CYS 282 282 282 CYS CYS A . n 
A 1 283 PRO 283 283 283 PRO PRO A . n 
A 1 284 THR 284 284 284 THR THR A . n 
A 1 285 VAL 285 285 285 VAL VAL A . n 
A 1 286 GLN 286 286 286 GLN GLN A . n 
A 1 287 LEU 287 287 287 LEU LEU A . n 
A 1 288 GLU 288 288 288 GLU GLU A . n 
A 1 289 GLU 289 289 289 GLU GLU A . n 
A 1 290 ILE 290 290 290 ILE ILE A . n 
A 1 291 SER 291 291 291 SER SER A . n 
A 1 292 ASN 292 292 292 ASN ASN A . n 
A 1 293 HIS 293 293 293 HIS HIS A . n 
A 1 294 GLN 294 294 294 GLN GLN A . n 
A 1 295 GLY 295 295 295 GLY GLY A . n 
A 1 296 LEU 296 296 296 LEU LEU A . n 
A 1 297 THR 297 297 297 THR THR A . n 
A 1 298 PRO 298 298 298 PRO PRO A . n 
A 1 299 LEU 299 299 299 LEU LEU A . n 
A 1 300 LYS 300 300 300 LYS LYS A . n 
A 1 301 LEU 301 301 301 LEU LEU A . n 
A 1 302 ALA 302 302 302 ALA ALA A . n 
A 1 303 ALA 303 303 303 ALA ALA A . n 
A 1 304 LYS 304 304 304 LYS LYS A . n 
A 1 305 GLU 305 305 305 GLU GLU A . n 
A 1 306 GLY 306 306 306 GLY GLY A . n 
A 1 307 LYS 307 307 307 LYS LYS A . n 
A 1 308 ILE 308 308 308 ILE ILE A . n 
A 1 309 GLU 309 309 309 GLU GLU A . n 
A 1 310 ILE 310 310 310 ILE ILE A . n 
A 1 311 PHE 311 311 311 PHE PHE A . n 
A 1 312 ARG 312 312 312 ARG ARG A . n 
A 1 313 HIS 313 313 313 HIS HIS A . n 
A 1 314 ILE 314 314 314 ILE ILE A . n 
A 1 315 LEU 315 315 315 LEU LEU A . n 
A 1 316 GLN 316 316 316 GLN GLN A . n 
A 1 317 ARG 317 317 317 ARG ARG A . n 
A 1 318 GLU 318 318 318 GLU GLU A . n 
A 1 319 PHE 319 319 319 PHE PHE A . n 
A 1 320 SER 320 320 320 SER SER A . n 
A 1 321 GLY 321 321 321 GLY GLY A . n 
A 1 322 PRO 322 322 322 PRO PRO A . n 
A 1 323 TYR 323 323 323 TYR TYR A . n 
A 1 324 GLN 324 324 324 GLN GLN A . n 
A 1 325 PRO 325 325 325 PRO PRO A . n 
A 1 326 LEU 326 326 326 LEU LEU A . n 
A 1 327 SER 327 327 327 SER SER A . n 
A 1 328 ARG 328 328 328 ARG ARG A . n 
A 1 329 LYS 329 329 329 LYS LYS A . n 
A 1 330 PHE 330 330 330 PHE PHE A . n 
A 1 331 THR 331 331 331 THR THR A . n 
A 1 332 GLU 332 332 332 GLU GLU A . n 
A 1 333 TRP 333 333 333 TRP TRP A . n 
A 1 334 CYS 334 334 334 CYS CYS A . n 
A 1 335 TYR 335 335 335 TYR TYR A . n 
A 1 336 GLY 336 336 336 GLY GLY A . n 
A 1 337 PRO 337 337 337 PRO PRO A . n 
A 1 338 VAL 338 338 338 VAL VAL A . n 
A 1 339 ARG 339 339 339 ARG ARG A . n 
A 1 340 VAL 340 340 340 VAL VAL A . n 
A 1 341 SER 341 341 341 SER SER A . n 
A 1 342 LEU 342 342 342 LEU LEU A . n 
A 1 343 TYR 343 343 343 TYR TYR A . n 
A 1 344 ASP 344 344 344 ASP ASP A . n 
A 1 345 LEU 345 345 345 LEU LEU A . n 
A 1 346 SER 346 346 346 SER SER A . n 
A 1 347 SER 347 347 347 SER SER A . n 
A 1 348 VAL 348 348 348 VAL VAL A . n 
A 1 349 ASP 349 349 349 ASP ASP A . n 
A 1 350 SER 350 350 350 SER SER A . n 
A 1 351 TRP 351 351 351 TRP TRP A . n 
A 1 352 GLU 352 352 352 GLU GLU A . n 
A 1 353 LYS 353 353 353 LYS LYS A . n 
A 1 354 ASN 354 354 354 ASN ASN A . n 
A 1 355 SER 355 355 355 SER SER A . n 
A 1 356 VAL 356 356 356 VAL VAL A . n 
A 1 357 LEU 357 357 357 LEU LEU A . n 
A 1 358 GLU 358 358 358 GLU GLU A . n 
A 1 359 ILE 359 359 359 ILE ILE A . n 
A 1 360 ILE 360 360 360 ILE ILE A . n 
A 1 361 ALA 361 361 361 ALA ALA A . n 
A 1 362 PHE 362 362 362 PHE PHE A . n 
A 1 363 HIS 363 363 363 HIS HIS A . n 
A 1 364 CYS 364 364 364 CYS CYS A . n 
A 1 365 LYS 365 365 365 LYS LYS A . n 
A 1 366 SER 366 366 366 SER SER A . n 
A 1 367 PRO 367 367 367 PRO PRO A . n 
A 1 368 ASN 368 368 368 ASN ASN A . n 
A 1 369 ARG 369 369 369 ARG ARG A . n 
A 1 370 HIS 370 370 370 HIS HIS A . n 
A 1 371 ARG 371 371 371 ARG ARG A . n 
A 1 372 MET 372 372 372 MET MET A . n 
A 1 373 VAL 373 373 373 VAL VAL A . n 
A 1 374 VAL 374 374 374 VAL VAL A . n 
A 1 375 LEU 375 375 375 LEU LEU A . n 
A 1 376 GLU 376 376 376 GLU GLU A . n 
A 1 377 PRO 377 377 377 PRO PRO A . n 
A 1 378 LEU 378 378 378 LEU LEU A . n 
A 1 379 ASN 379 379 379 ASN ASN A . n 
A 1 380 LYS 380 380 380 LYS LYS A . n 
A 1 381 LEU 381 381 381 LEU LEU A . n 
A 1 382 LEU 382 382 382 LEU LEU A . n 
A 1 383 GLN 383 383 383 GLN GLN A . n 
A 1 384 GLU 384 384 384 GLU GLU A . n 
A 1 385 LYS 385 385 385 LYS LYS A . n 
A 1 386 TRP 386 386 386 TRP TRP A . n 
A 1 387 ASP 387 387 387 ASP ASP A . n 
A 1 388 ARG 388 388 388 ARG ARG A . n 
A 1 389 LEU 389 389 389 LEU LEU A . n 
A 1 390 VAL 390 390 390 VAL VAL A . n 
A 1 391 SER 391 391 391 SER SER A . n 
A 1 392 ARG 392 392 392 ARG ARG A . n 
A 1 393 PHE 393 393 393 PHE PHE A . n 
A 1 394 PHE 394 394 394 PHE PHE A . n 
A 1 395 PHE 395 395 395 PHE PHE A . n 
A 1 396 ASN 396 396 396 ASN ASN A . n 
A 1 397 PHE 397 397 397 PHE PHE A . n 
A 1 398 ALA 398 398 398 ALA ALA A . n 
A 1 399 CYS 399 399 399 CYS CYS A . n 
A 1 400 TYR 400 400 400 TYR TYR A . n 
A 1 401 LEU 401 401 401 LEU LEU A . n 
A 1 402 VAL 402 402 402 VAL VAL A . n 
A 1 403 TYR 403 403 403 TYR TYR A . n 
A 1 404 MET 404 404 404 MET MET A . n 
A 1 405 PHE 405 405 405 PHE PHE A . n 
A 1 406 ILE 406 406 406 ILE ILE A . n 
A 1 407 PHE 407 407 407 PHE PHE A . n 
A 1 408 THR 408 408 408 THR THR A . n 
A 1 409 VAL 409 409 409 VAL VAL A . n 
A 1 410 VAL 410 410 410 VAL VAL A . n 
A 1 411 ALA 411 411 411 ALA ALA A . n 
A 1 412 TYR 412 412 412 TYR TYR A . n 
A 1 413 HIS 413 413 413 HIS HIS A . n 
A 1 414 GLN 414 414 414 GLN GLN A . n 
A 1 415 PRO 415 415 415 PRO PRO A . n 
A 1 416 SER 416 416 416 SER SER A . n 
A 1 417 LEU 417 417 417 LEU LEU A . n 
A 1 418 ASP 418 418 ?   ?   ?   A . n 
A 1 419 GLN 419 419 ?   ?   ?   A . n 
A 1 420 PRO 420 420 ?   ?   ?   A . n 
A 1 421 ALA 421 421 ?   ?   ?   A . n 
A 1 422 ILE 422 422 ?   ?   ?   A . n 
A 1 423 PRO 423 423 ?   ?   ?   A . n 
A 1 424 SER 424 424 ?   ?   ?   A . n 
A 1 425 SER 425 425 ?   ?   ?   A . n 
A 1 426 LYS 426 426 ?   ?   ?   A . n 
A 1 427 ALA 427 427 ?   ?   ?   A . n 
A 1 428 THR 428 428 ?   ?   ?   A . n 
A 1 429 PHE 429 429 429 PHE PHE A . n 
A 1 430 GLY 430 430 430 GLY GLY A . n 
A 1 431 GLU 431 431 431 GLU GLU A . n 
A 1 432 SER 432 432 432 SER SER A . n 
A 1 433 MET 433 433 433 MET MET A . n 
A 1 434 LEU 434 434 434 LEU LEU A . n 
A 1 435 LEU 435 435 435 LEU LEU A . n 
A 1 436 LEU 436 436 436 LEU LEU A . n 
A 1 437 GLY 437 437 437 GLY GLY A . n 
A 1 438 HIS 438 438 438 HIS HIS A . n 
A 1 439 ILE 439 439 439 ILE ILE A . n 
A 1 440 LEU 440 440 440 LEU LEU A . n 
A 1 441 ILE 441 441 441 ILE ILE A . n 
A 1 442 LEU 442 442 442 LEU LEU A . n 
A 1 443 LEU 443 443 443 LEU LEU A . n 
A 1 444 GLY 444 444 444 GLY GLY A . n 
A 1 445 GLY 445 445 445 GLY GLY A . n 
A 1 446 ILE 446 446 446 ILE ILE A . n 
A 1 447 TYR 447 447 447 TYR TYR A . n 
A 1 448 LEU 448 448 448 LEU LEU A . n 
A 1 449 LEU 449 449 449 LEU LEU A . n 
A 1 450 LEU 450 450 450 LEU LEU A . n 
A 1 451 GLY 451 451 451 GLY GLY A . n 
A 1 452 GLN 452 452 452 GLN GLN A . n 
A 1 453 LEU 453 453 453 LEU LEU A . n 
A 1 454 TRP 454 454 454 TRP TRP A . n 
A 1 455 TYR 455 455 455 TYR TYR A . n 
A 1 456 PHE 456 456 456 PHE PHE A . n 
A 1 457 TRP 457 457 457 TRP TRP A . n 
A 1 458 ARG 458 458 458 ARG ARG A . n 
A 1 459 ARG 459 459 459 ARG ARG A . n 
A 1 460 ARG 460 460 460 ARG ARG A . n 
A 1 461 LEU 461 461 461 LEU LEU A . n 
A 1 462 PHE 462 462 462 PHE PHE A . n 
A 1 463 ILE 463 463 463 ILE ILE A . n 
A 1 464 TRP 464 464 464 TRP TRP A . n 
A 1 465 ILE 465 465 465 ILE ILE A . n 
A 1 466 SER 466 466 466 SER SER A . n 
A 1 467 PHE 467 467 467 PHE PHE A . n 
A 1 468 MET 468 468 468 MET MET A . n 
A 1 469 ASP 469 469 469 ASP ASP A . n 
A 1 470 SER 470 470 470 SER SER A . n 
A 1 471 TYR 471 471 471 TYR TYR A . n 
A 1 472 PHE 472 472 472 PHE PHE A . n 
A 1 473 GLU 473 473 473 GLU GLU A . n 
A 1 474 ILE 474 474 474 ILE ILE A . n 
A 1 475 LEU 475 475 475 LEU LEU A . n 
A 1 476 PHE 476 476 476 PHE PHE A . n 
A 1 477 LEU 477 477 477 LEU LEU A . n 
A 1 478 LEU 478 478 478 LEU LEU A . n 
A 1 479 GLN 479 479 479 GLN GLN A . n 
A 1 480 ALA 480 480 480 ALA ALA A . n 
A 1 481 LEU 481 481 481 LEU LEU A . n 
A 1 482 LEU 482 482 482 LEU LEU A . n 
A 1 483 THR 483 483 483 THR THR A . n 
A 1 484 VAL 484 484 484 VAL VAL A . n 
A 1 485 LEU 485 485 485 LEU LEU A . n 
A 1 486 SER 486 486 486 SER SER A . n 
A 1 487 GLN 487 487 487 GLN GLN A . n 
A 1 488 VAL 488 488 488 VAL VAL A . n 
A 1 489 LEU 489 489 489 LEU LEU A . n 
A 1 490 ARG 490 490 490 ARG ARG A . n 
A 1 491 PHE 491 491 491 PHE PHE A . n 
A 1 492 MET 492 492 492 MET MET A . n 
A 1 493 GLU 493 493 493 GLU GLU A . n 
A 1 494 THR 494 494 494 THR THR A . n 
A 1 495 GLU 495 495 495 GLU GLU A . n 
A 1 496 TRP 496 496 496 TRP TRP A . n 
A 1 497 TYR 497 497 497 TYR TYR A . n 
A 1 498 LEU 498 498 498 LEU LEU A . n 
A 1 499 PRO 499 499 499 PRO PRO A . n 
A 1 500 LEU 500 500 500 LEU LEU A . n 
A 1 501 LEU 501 501 501 LEU LEU A . n 
A 1 502 VAL 502 502 502 VAL VAL A . n 
A 1 503 LEU 503 503 503 LEU LEU A . n 
A 1 504 SER 504 504 504 SER SER A . n 
A 1 505 LEU 505 505 505 LEU LEU A . n 
A 1 506 VAL 506 506 506 VAL VAL A . n 
A 1 507 LEU 507 507 507 LEU LEU A . n 
A 1 508 GLY 508 508 508 GLY GLY A . n 
A 1 509 TRP 509 509 509 TRP TRP A . n 
A 1 510 LEU 510 510 510 LEU LEU A . n 
A 1 511 ASN 511 511 511 ASN ASN A . n 
A 1 512 LEU 512 512 512 LEU LEU A . n 
A 1 513 LEU 513 513 513 LEU LEU A . n 
A 1 514 TYR 514 514 514 TYR TYR A . n 
A 1 515 TYR 515 515 515 TYR TYR A . n 
A 1 516 THR 516 516 516 THR THR A . n 
A 1 517 ARG 517 517 517 ARG ARG A . n 
A 1 518 GLY 518 518 518 GLY GLY A . n 
A 1 519 PHE 519 519 519 PHE PHE A . n 
A 1 520 GLN 520 520 520 GLN GLN A . n 
A 1 521 HIS 521 521 521 HIS HIS A . n 
A 1 522 THR 522 522 522 THR THR A . n 
A 1 523 GLY 523 523 523 GLY GLY A . n 
A 1 524 ILE 524 524 524 ILE ILE A . n 
A 1 525 TYR 525 525 525 TYR TYR A . n 
A 1 526 SER 526 526 526 SER SER A . n 
A 1 527 VAL 527 527 527 VAL VAL A . n 
A 1 528 MET 528 528 528 MET MET A . n 
A 1 529 ILE 529 529 529 ILE ILE A . n 
A 1 530 GLN 530 530 530 GLN GLN A . n 
A 1 531 LYS 531 531 531 LYS LYS A . n 
A 1 532 VAL 532 532 532 VAL VAL A . n 
A 1 533 ILE 533 533 533 ILE ILE A . n 
A 1 534 LEU 534 534 534 LEU LEU A . n 
A 1 535 ARG 535 535 535 ARG ARG A . n 
A 1 536 ASP 536 536 536 ASP ASP A . n 
A 1 537 LEU 537 537 537 LEU LEU A . n 
A 1 538 LEU 538 538 538 LEU LEU A . n 
A 1 539 ARG 539 539 539 ARG ARG A . n 
A 1 540 PHE 540 540 540 PHE PHE A . n 
A 1 541 LEU 541 541 541 LEU LEU A . n 
A 1 542 LEU 542 542 542 LEU LEU A . n 
A 1 543 VAL 543 543 543 VAL VAL A . n 
A 1 544 TYR 544 544 544 TYR TYR A . n 
A 1 545 LEU 545 545 545 LEU LEU A . n 
A 1 546 VAL 546 546 546 VAL VAL A . n 
A 1 547 PHE 547 547 547 PHE PHE A . n 
A 1 548 LEU 548 548 548 LEU LEU A . n 
A 1 549 PHE 549 549 549 PHE PHE A . n 
A 1 550 GLY 550 550 550 GLY GLY A . n 
A 1 551 PHE 551 551 551 PHE PHE A . n 
A 1 552 ALA 552 552 552 ALA ALA A . n 
A 1 553 VAL 553 553 553 VAL VAL A . n 
A 1 554 ALA 554 554 554 ALA ALA A . n 
A 1 555 LEU 555 555 555 LEU LEU A . n 
A 1 556 VAL 556 556 556 VAL VAL A . n 
A 1 557 SER 557 557 557 SER SER A . n 
A 1 558 LEU 558 558 558 LEU LEU A . n 
A 1 559 SER 559 559 559 SER SER A . n 
A 1 560 ARG 560 560 560 ARG ARG A . n 
A 1 561 GLU 561 561 561 GLU GLU A . n 
A 1 562 ALA 562 562 562 ALA ALA A . n 
A 1 563 ARG 563 563 563 ARG ARG A . n 
A 1 564 SER 564 564 ?   ?   ?   A . n 
A 1 565 PRO 565 565 ?   ?   ?   A . n 
A 1 566 LYS 566 566 ?   ?   ?   A . n 
A 1 567 ALA 567 567 ?   ?   ?   A . n 
A 1 568 PRO 568 568 ?   ?   ?   A . n 
A 1 569 GLU 569 569 ?   ?   ?   A . n 
A 1 570 ASP 570 570 ?   ?   ?   A . n 
A 1 571 ASN 571 571 ?   ?   ?   A . n 
A 1 572 ASN 572 572 ?   ?   ?   A . n 
A 1 573 SER 573 573 ?   ?   ?   A . n 
A 1 574 THR 574 574 ?   ?   ?   A . n 
A 1 575 VAL 575 575 ?   ?   ?   A . n 
A 1 576 THR 576 576 ?   ?   ?   A . n 
A 1 577 GLU 577 577 ?   ?   ?   A . n 
A 1 578 GLN 578 578 ?   ?   ?   A . n 
A 1 579 PRO 579 579 ?   ?   ?   A . n 
A 1 580 THR 580 580 ?   ?   ?   A . n 
A 1 581 VAL 581 581 ?   ?   ?   A . n 
A 1 582 GLY 582 582 ?   ?   ?   A . n 
A 1 583 GLN 583 583 ?   ?   ?   A . n 
A 1 584 GLU 584 584 ?   ?   ?   A . n 
A 1 585 GLU 585 585 ?   ?   ?   A . n 
A 1 586 GLU 586 586 ?   ?   ?   A . n 
A 1 587 PRO 587 587 ?   ?   ?   A . n 
A 1 588 ALA 588 588 ?   ?   ?   A . n 
A 1 589 PRO 589 589 589 PRO PRO A . n 
A 1 590 TYR 590 590 590 TYR TYR A . n 
A 1 591 ARG 591 591 591 ARG ARG A . n 
A 1 592 SER 592 592 592 SER SER A . n 
A 1 593 ILE 593 593 593 ILE ILE A . n 
A 1 594 LEU 594 594 594 LEU LEU A . n 
A 1 595 ASP 595 595 595 ASP ASP A . n 
A 1 596 ALA 596 596 596 ALA ALA A . n 
A 1 597 SER 597 597 597 SER SER A . n 
A 1 598 LEU 598 598 598 LEU LEU A . n 
A 1 599 GLU 599 599 599 GLU GLU A . n 
A 1 600 LEU 600 600 600 LEU LEU A . n 
A 1 601 PHE 601 601 601 PHE PHE A . n 
A 1 602 LYS 602 602 602 LYS LYS A . n 
A 1 603 PHE 603 603 603 PHE PHE A . n 
A 1 604 THR 604 604 604 THR THR A . n 
A 1 605 ILE 605 605 605 ILE ILE A . n 
A 1 606 GLY 606 606 606 GLY GLY A . n 
A 1 607 MET 607 607 607 MET MET A . n 
A 1 608 GLY 608 608 608 GLY GLY A . n 
A 1 609 GLU 609 609 609 GLU GLU A . n 
A 1 610 LEU 610 610 610 LEU LEU A . n 
A 1 611 ALA 611 611 611 ALA ALA A . n 
A 1 612 PHE 612 612 612 PHE PHE A . n 
A 1 613 GLN 613 613 613 GLN GLN A . n 
A 1 614 GLU 614 614 614 GLU GLU A . n 
A 1 615 GLN 615 615 615 GLN GLN A . n 
A 1 616 LEU 616 616 616 LEU LEU A . n 
A 1 617 ARG 617 617 617 ARG ARG A . n 
A 1 618 PHE 618 618 618 PHE PHE A . n 
A 1 619 ARG 619 619 619 ARG ARG A . n 
A 1 620 GLY 620 620 620 GLY GLY A . n 
A 1 621 VAL 621 621 621 VAL VAL A . n 
A 1 622 VAL 622 622 622 VAL VAL A . n 
A 1 623 LEU 623 623 623 LEU LEU A . n 
A 1 624 LEU 624 624 624 LEU LEU A . n 
A 1 625 LEU 625 625 625 LEU LEU A . n 
A 1 626 LEU 626 626 626 LEU LEU A . n 
A 1 627 LEU 627 627 627 LEU LEU A . n 
A 1 628 ALA 628 628 628 ALA ALA A . n 
A 1 629 TYR 629 629 629 TYR TYR A . n 
A 1 630 VAL 630 630 630 VAL VAL A . n 
A 1 631 LEU 631 631 631 LEU LEU A . n 
A 1 632 LEU 632 632 632 LEU LEU A . n 
A 1 633 THR 633 633 633 THR THR A . n 
A 1 634 TYR 634 634 634 TYR TYR A . n 
A 1 635 VAL 635 635 635 VAL VAL A . n 
A 1 636 LEU 636 636 636 LEU LEU A . n 
A 1 637 LEU 637 637 637 LEU LEU A . n 
A 1 638 LEU 638 638 638 LEU LEU A . n 
A 1 639 ASN 639 639 639 ASN ASN A . n 
A 1 640 MET 640 640 640 MET MET A . n 
A 1 641 LEU 641 641 641 LEU LEU A . n 
A 1 642 ILE 642 642 642 ILE ILE A . n 
A 1 643 ALA 643 643 643 ALA ALA A . n 
A 1 644 LEU 644 644 644 LEU LEU A . n 
A 1 645 MET 645 645 645 MET MET A . n 
A 1 646 SER 646 646 646 SER SER A . n 
A 1 647 GLU 647 647 647 GLU GLU A . n 
A 1 648 THR 648 648 648 THR THR A . n 
A 1 649 VAL 649 649 649 VAL VAL A . n 
A 1 650 ASN 650 650 650 ASN ASN A . n 
A 1 651 HIS 651 651 651 HIS HIS A . n 
A 1 652 VAL 652 652 652 VAL VAL A . n 
A 1 653 ALA 653 653 653 ALA ALA A . n 
A 1 654 ASP 654 654 654 ASP ASP A . n 
A 1 655 ASN 655 655 655 ASN ASN A . n 
A 1 656 SER 656 656 656 SER SER A . n 
A 1 657 TRP 657 657 657 TRP TRP A . n 
A 1 658 SER 658 658 658 SER SER A . n 
A 1 659 ILE 659 659 659 ILE ILE A . n 
A 1 660 TRP 660 660 660 TRP TRP A . n 
A 1 661 LYS 661 661 661 LYS LYS A . n 
A 1 662 LEU 662 662 662 LEU LEU A . n 
A 1 663 GLN 663 663 663 GLN GLN A . n 
A 1 664 LYS 664 664 664 LYS LYS A . n 
A 1 665 ALA 665 665 665 ALA ALA A . n 
A 1 666 ILE 666 666 666 ILE ILE A . n 
A 1 667 SER 667 667 667 SER SER A . n 
A 1 668 VAL 668 668 668 VAL VAL A . n 
A 1 669 LEU 669 669 669 LEU LEU A . n 
A 1 670 GLU 670 670 670 GLU GLU A . n 
A 1 671 MET 671 671 671 MET MET A . n 
A 1 672 GLU 672 672 672 GLU GLU A . n 
A 1 673 ASN 673 673 673 ASN ASN A . n 
A 1 674 GLY 674 674 674 GLY GLY A . n 
A 1 675 TYR 675 675 675 TYR TYR A . n 
A 1 676 TRP 676 676 676 TRP TRP A . n 
A 1 677 TRP 677 677 677 TRP TRP A . n 
A 1 678 CYS 678 678 678 CYS CYS A . n 
A 1 679 ARG 679 679 679 ARG ARG A . n 
A 1 680 ARG 680 680 680 ARG ARG A . n 
A 1 681 LYS 681 681 681 LYS LYS A . n 
A 1 682 LYS 682 682 682 LYS LYS A . n 
A 1 683 HIS 683 683 683 HIS HIS A . n 
A 1 684 ARG 684 684 684 ARG ARG A . n 
A 1 685 GLU 685 685 685 GLU GLU A . n 
A 1 686 GLY 686 686 686 GLY GLY A . n 
A 1 687 ARG 687 687 687 ARG ARG A . n 
A 1 688 LEU 688 688 688 LEU LEU A . n 
A 1 689 LEU 689 689 689 LEU LEU A . n 
A 1 690 LYS 690 690 690 LYS LYS A . n 
A 1 691 VAL 691 691 691 VAL VAL A . n 
A 1 692 GLY 692 692 692 GLY GLY A . n 
A 1 693 THR 693 693 693 THR THR A . n 
A 1 694 ARG 694 694 694 ARG ARG A . n 
A 1 695 GLY 695 695 ?   ?   ?   A . n 
A 1 696 ASP 696 696 ?   ?   ?   A . n 
A 1 697 GLY 697 697 ?   ?   ?   A . n 
A 1 698 THR 698 698 ?   ?   ?   A . n 
A 1 699 PRO 699 699 699 PRO PRO A . n 
A 1 700 ASP 700 700 700 ASP ASP A . n 
A 1 701 GLU 701 701 701 GLU GLU A . n 
A 1 702 ARG 702 702 702 ARG ARG A . n 
A 1 703 TRP 703 703 703 TRP TRP A . n 
A 1 704 CYS 704 704 704 CYS CYS A . n 
A 1 705 PHE 705 705 705 PHE PHE A . n 
A 1 706 ARG 706 706 706 ARG ARG A . n 
A 1 707 VAL 707 707 707 VAL VAL A . n 
A 1 708 GLU 708 708 708 GLU GLU A . n 
A 1 709 GLU 709 709 709 GLU GLU A . n 
A 1 710 VAL 710 710 710 VAL VAL A . n 
A 1 711 ASN 711 711 711 ASN ASN A . n 
A 1 712 TRP 712 712 712 TRP TRP A . n 
A 1 713 ALA 713 713 713 ALA ALA A . n 
A 1 714 ALA 714 714 714 ALA ALA A . n 
A 1 715 TRP 715 715 715 TRP TRP A . n 
A 1 716 GLU 716 716 716 GLU GLU A . n 
A 1 717 LYS 717 717 717 LYS LYS A . n 
A 1 718 THR 718 718 718 THR THR A . n 
A 1 719 LEU 719 719 719 LEU LEU A . n 
A 1 720 PRO 720 720 ?   ?   ?   A . n 
A 1 721 THR 721 721 ?   ?   ?   A . n 
A 1 722 LEU 722 722 ?   ?   ?   A . n 
A 1 723 SER 723 723 ?   ?   ?   A . n 
A 1 724 GLU 724 724 ?   ?   ?   A . n 
A 1 725 ASP 725 725 ?   ?   ?   A . n 
A 1 726 PRO 726 726 ?   ?   ?   A . n 
A 1 727 SER 727 727 ?   ?   ?   A . n 
A 1 728 GLY 728 728 ?   ?   ?   A . n 
A 1 729 PRO 729 729 ?   ?   ?   A . n 
A 1 730 GLY 730 730 ?   ?   ?   A . n 
A 1 731 ILE 731 731 ?   ?   ?   A . n 
A 1 732 THR 732 732 ?   ?   ?   A . n 
A 1 733 GLY 733 733 ?   ?   ?   A . n 
A 1 734 ASN 734 734 ?   ?   ?   A . n 
A 1 735 LYS 735 735 ?   ?   ?   A . n 
A 1 736 LYS 736 736 ?   ?   ?   A . n 
A 1 737 ASN 737 737 ?   ?   ?   A . n 
A 1 738 PRO 738 738 ?   ?   ?   A . n 
A 1 739 THR 739 739 ?   ?   ?   A . n 
A 1 740 SER 740 740 ?   ?   ?   A . n 
A 1 741 LYS 741 741 ?   ?   ?   A . n 
A 1 742 PRO 742 742 ?   ?   ?   A . n 
A 1 743 GLY 743 743 ?   ?   ?   A . n 
A 1 744 LYS 744 744 ?   ?   ?   A . n 
A 1 745 ASN 745 745 ?   ?   ?   A . n 
A 1 746 SER 746 746 ?   ?   ?   A . n 
A 1 747 ALA 747 747 ?   ?   ?   A . n 
A 1 748 SER 748 748 ?   ?   ?   A . n 
A 1 749 GLU 749 749 ?   ?   ?   A . n 
A 1 750 GLU 750 750 ?   ?   ?   A . n 
A 1 751 ASP 751 751 ?   ?   ?   A . n 
A 1 752 HIS 752 752 ?   ?   ?   A . n 
A 1 753 LEU 753 753 ?   ?   ?   A . n 
A 1 754 PRO 754 754 ?   ?   ?   A . n 
A 1 755 LEU 755 755 ?   ?   ?   A . n 
A 1 756 GLN 756 756 ?   ?   ?   A . n 
A 1 757 VAL 757 757 ?   ?   ?   A . n 
A 1 758 LEU 758 758 ?   ?   ?   A . n 
A 1 759 GLN 759 759 ?   ?   ?   A . n 
A 1 760 SER 760 760 ?   ?   ?   A . n 
A 1 761 PRO 761 761 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   THR 2   2   ?   ?   ?   B . n 
B 1 3   SER 3   3   ?   ?   ?   B . n 
B 1 4   ALA 4   4   ?   ?   ?   B . n 
B 1 5   SER 5   5   ?   ?   ?   B . n 
B 1 6   SER 6   6   ?   ?   ?   B . n 
B 1 7   PRO 7   7   ?   ?   ?   B . n 
B 1 8   PRO 8   8   ?   ?   ?   B . n 
B 1 9   ALA 9   9   ?   ?   ?   B . n 
B 1 10  PHE 10  10  ?   ?   ?   B . n 
B 1 11  ARG 11  11  ?   ?   ?   B . n 
B 1 12  LEU 12  12  ?   ?   ?   B . n 
B 1 13  GLU 13  13  ?   ?   ?   B . n 
B 1 14  THR 14  14  ?   ?   ?   B . n 
B 1 15  SER 15  15  ?   ?   ?   B . n 
B 1 16  ASP 16  16  ?   ?   ?   B . n 
B 1 17  GLY 17  17  ?   ?   ?   B . n 
B 1 18  ASP 18  18  ?   ?   ?   B . n 
B 1 19  GLU 19  19  ?   ?   ?   B . n 
B 1 20  GLU 20  20  ?   ?   ?   B . n 
B 1 21  GLY 21  21  ?   ?   ?   B . n 
B 1 22  ASN 22  22  ?   ?   ?   B . n 
B 1 23  ALA 23  23  ?   ?   ?   B . n 
B 1 24  GLU 24  24  ?   ?   ?   B . n 
B 1 25  VAL 25  25  ?   ?   ?   B . n 
B 1 26  ASN 26  26  ?   ?   ?   B . n 
B 1 27  LYS 27  27  ?   ?   ?   B . n 
B 1 28  GLY 28  28  ?   ?   ?   B . n 
B 1 29  LYS 29  29  ?   ?   ?   B . n 
B 1 30  GLN 30  30  ?   ?   ?   B . n 
B 1 31  GLU 31  31  ?   ?   ?   B . n 
B 1 32  PRO 32  32  ?   ?   ?   B . n 
B 1 33  PRO 33  33  ?   ?   ?   B . n 
B 1 34  PRO 34  34  ?   ?   ?   B . n 
B 1 35  MET 35  35  ?   ?   ?   B . n 
B 1 36  GLU 36  36  ?   ?   ?   B . n 
B 1 37  SER 37  37  ?   ?   ?   B . n 
B 1 38  PRO 38  38  ?   ?   ?   B . n 
B 1 39  PHE 39  39  ?   ?   ?   B . n 
B 1 40  GLN 40  40  ?   ?   ?   B . n 
B 1 41  ARG 41  41  ?   ?   ?   B . n 
B 1 42  GLU 42  42  ?   ?   ?   B . n 
B 1 43  ASP 43  43  ?   ?   ?   B . n 
B 1 44  ARG 44  44  ?   ?   ?   B . n 
B 1 45  ASN 45  45  ?   ?   ?   B . n 
B 1 46  SER 46  46  ?   ?   ?   B . n 
B 1 47  SER 47  47  ?   ?   ?   B . n 
B 1 48  PRO 48  48  ?   ?   ?   B . n 
B 1 49  GLN 49  49  ?   ?   ?   B . n 
B 1 50  ILE 50  50  ?   ?   ?   B . n 
B 1 51  LYS 51  51  ?   ?   ?   B . n 
B 1 52  VAL 52  52  ?   ?   ?   B . n 
B 1 53  ASN 53  53  ?   ?   ?   B . n 
B 1 54  LEU 54  54  ?   ?   ?   B . n 
B 1 55  ASN 55  55  ?   ?   ?   B . n 
B 1 56  PHE 56  56  ?   ?   ?   B . n 
B 1 57  ILE 57  57  ?   ?   ?   B . n 
B 1 58  LYS 58  58  ?   ?   ?   B . n 
B 1 59  ARG 59  59  ?   ?   ?   B . n 
B 1 60  PRO 60  60  ?   ?   ?   B . n 
B 1 61  PRO 61  61  ?   ?   ?   B . n 
B 1 62  LYS 62  62  ?   ?   ?   B . n 
B 1 63  ASN 63  63  ?   ?   ?   B . n 
B 1 64  THR 64  64  ?   ?   ?   B . n 
B 1 65  SER 65  65  ?   ?   ?   B . n 
B 1 66  ALA 66  66  ?   ?   ?   B . n 
B 1 67  PRO 67  67  ?   ?   ?   B . n 
B 1 68  SER 68  68  ?   ?   ?   B . n 
B 1 69  GLN 69  69  ?   ?   ?   B . n 
B 1 70  GLN 70  70  ?   ?   ?   B . n 
B 1 71  GLU 71  71  ?   ?   ?   B . n 
B 1 72  PRO 72  72  ?   ?   ?   B . n 
B 1 73  ASP 73  73  ?   ?   ?   B . n 
B 1 74  ARG 74  74  74  ARG ARG B . n 
B 1 75  PHE 75  75  75  PHE PHE B . n 
B 1 76  ASP 76  76  76  ASP ASP B . n 
B 1 77  ARG 77  77  77  ARG ARG B . n 
B 1 78  ASP 78  78  78  ASP ASP B . n 
B 1 79  ARG 79  79  79  ARG ARG B . n 
B 1 80  LEU 80  80  80  LEU LEU B . n 
B 1 81  PHE 81  81  81  PHE PHE B . n 
B 1 82  SER 82  82  82  SER SER B . n 
B 1 83  VAL 83  83  83  VAL VAL B . n 
B 1 84  VAL 84  84  84  VAL VAL B . n 
B 1 85  SER 85  85  85  SER SER B . n 
B 1 86  ARG 86  86  86  ARG ARG B . n 
B 1 87  GLY 87  87  87  GLY GLY B . n 
B 1 88  VAL 88  88  88  VAL VAL B . n 
B 1 89  PRO 89  89  89  PRO PRO B . n 
B 1 90  GLU 90  90  90  GLU GLU B . n 
B 1 91  GLU 91  91  91  GLU GLU B . n 
B 1 92  LEU 92  92  92  LEU LEU B . n 
B 1 93  THR 93  93  93  THR THR B . n 
B 1 94  GLY 94  94  94  GLY GLY B . n 
B 1 95  LEU 95  95  95  LEU LEU B . n 
B 1 96  LEU 96  96  96  LEU LEU B . n 
B 1 97  GLU 97  97  97  GLU GLU B . n 
B 1 98  TYR 98  98  98  TYR TYR B . n 
B 1 99  LEU 99  99  99  LEU LEU B . n 
B 1 100 ARG 100 100 100 ARG ARG B . n 
B 1 101 TRP 101 101 101 TRP TRP B . n 
B 1 102 ASN 102 102 102 ASN ASN B . n 
B 1 103 SER 103 103 103 SER SER B . n 
B 1 104 LYS 104 104 104 LYS LYS B . n 
B 1 105 TYR 105 105 105 TYR TYR B . n 
B 1 106 LEU 106 106 106 LEU LEU B . n 
B 1 107 THR 107 107 107 THR THR B . n 
B 1 108 ASP 108 108 108 ASP ASP B . n 
B 1 109 SER 109 109 109 SER SER B . n 
B 1 110 ALA 110 110 110 ALA ALA B . n 
B 1 111 TYR 111 111 111 TYR TYR B . n 
B 1 112 THR 112 112 112 THR THR B . n 
B 1 113 GLU 113 113 113 GLU GLU B . n 
B 1 114 GLY 114 114 114 GLY GLY B . n 
B 1 115 SER 115 115 115 SER SER B . n 
B 1 116 THR 116 116 116 THR THR B . n 
B 1 117 GLY 117 117 117 GLY GLY B . n 
B 1 118 LYS 118 118 118 LYS LYS B . n 
B 1 119 THR 119 119 119 THR THR B . n 
B 1 120 CYS 120 120 120 CYS CYS B . n 
B 1 121 LEU 121 121 121 LEU LEU B . n 
B 1 122 MET 122 122 122 MET MET B . n 
B 1 123 LYS 123 123 123 LYS LYS B . n 
B 1 124 ALA 124 124 124 ALA ALA B . n 
B 1 125 VAL 125 125 125 VAL VAL B . n 
B 1 126 LEU 126 126 126 LEU LEU B . n 
B 1 127 ASN 127 127 127 ASN ASN B . n 
B 1 128 LEU 128 128 128 LEU LEU B . n 
B 1 129 GLN 129 129 129 GLN GLN B . n 
B 1 130 ASP 130 130 130 ASP ASP B . n 
B 1 131 GLY 131 131 131 GLY GLY B . n 
B 1 132 VAL 132 132 132 VAL VAL B . n 
B 1 133 ASN 133 133 133 ASN ASN B . n 
B 1 134 ALA 134 134 134 ALA ALA B . n 
B 1 135 CYS 135 135 135 CYS CYS B . n 
B 1 136 ILE 136 136 136 ILE ILE B . n 
B 1 137 MET 137 137 137 MET MET B . n 
B 1 138 PRO 138 138 138 PRO PRO B . n 
B 1 139 LEU 139 139 139 LEU LEU B . n 
B 1 140 LEU 140 140 140 LEU LEU B . n 
B 1 141 GLN 141 141 141 GLN GLN B . n 
B 1 142 ILE 142 142 142 ILE ILE B . n 
B 1 143 ASP 143 143 143 ASP ASP B . n 
B 1 144 LYS 144 144 144 LYS LYS B . n 
B 1 145 ASP 145 145 145 ASP ASP B . n 
B 1 146 SER 146 146 146 SER SER B . n 
B 1 147 GLY 147 147 147 GLY GLY B . n 
B 1 148 ASN 148 148 148 ASN ASN B . n 
B 1 149 PRO 149 149 149 PRO PRO B . n 
B 1 150 LYS 150 150 150 LYS LYS B . n 
B 1 151 LEU 151 151 151 LEU LEU B . n 
B 1 152 LEU 152 152 152 LEU LEU B . n 
B 1 153 VAL 153 153 153 VAL VAL B . n 
B 1 154 ASN 154 154 154 ASN ASN B . n 
B 1 155 ALA 155 155 155 ALA ALA B . n 
B 1 156 GLN 156 156 156 GLN GLN B . n 
B 1 157 CYS 157 157 157 CYS CYS B . n 
B 1 158 THR 158 158 158 THR THR B . n 
B 1 159 ASP 159 159 159 ASP ASP B . n 
B 1 160 GLU 160 160 160 GLU GLU B . n 
B 1 161 PHE 161 161 161 PHE PHE B . n 
B 1 162 TYR 162 162 162 TYR TYR B . n 
B 1 163 GLN 163 163 163 GLN GLN B . n 
B 1 164 GLY 164 164 164 GLY GLY B . n 
B 1 165 HIS 165 165 165 HIS HIS B . n 
B 1 166 SER 166 166 166 SER SER B . n 
B 1 167 ALA 167 167 167 ALA ALA B . n 
B 1 168 LEU 168 168 168 LEU LEU B . n 
B 1 169 HIS 169 169 169 HIS HIS B . n 
B 1 170 ILE 170 170 170 ILE ILE B . n 
B 1 171 ALA 171 171 171 ALA ALA B . n 
B 1 172 ILE 172 172 172 ILE ILE B . n 
B 1 173 GLU 173 173 173 GLU GLU B . n 
B 1 174 LYS 174 174 174 LYS LYS B . n 
B 1 175 ARG 175 175 175 ARG ARG B . n 
B 1 176 SER 176 176 176 SER SER B . n 
B 1 177 LEU 177 177 177 LEU LEU B . n 
B 1 178 GLN 178 178 178 GLN GLN B . n 
B 1 179 CYS 179 179 179 CYS CYS B . n 
B 1 180 VAL 180 180 180 VAL VAL B . n 
B 1 181 LYS 181 181 181 LYS LYS B . n 
B 1 182 LEU 182 182 182 LEU LEU B . n 
B 1 183 LEU 183 183 183 LEU LEU B . n 
B 1 184 VAL 184 184 184 VAL VAL B . n 
B 1 185 GLU 185 185 185 GLU GLU B . n 
B 1 186 ASN 186 186 186 ASN ASN B . n 
B 1 187 GLY 187 187 187 GLY GLY B . n 
B 1 188 ALA 188 188 188 ALA ALA B . n 
B 1 189 ASP 189 189 189 ASP ASP B . n 
B 1 190 VAL 190 190 190 VAL VAL B . n 
B 1 191 HIS 191 191 191 HIS HIS B . n 
B 1 192 LEU 192 192 192 LEU LEU B . n 
B 1 193 ARG 193 193 193 ARG ARG B . n 
B 1 194 ALA 194 194 194 ALA ALA B . n 
B 1 195 CYS 195 195 195 CYS CYS B . n 
B 1 196 GLY 196 196 196 GLY GLY B . n 
B 1 197 ARG 197 197 197 ARG ARG B . n 
B 1 198 PHE 198 198 198 PHE PHE B . n 
B 1 199 PHE 199 199 199 PHE PHE B . n 
B 1 200 GLN 200 200 200 GLN GLN B . n 
B 1 201 LYS 201 201 201 LYS LYS B . n 
B 1 202 HIS 202 202 202 HIS HIS B . n 
B 1 203 GLN 203 203 203 GLN GLN B . n 
B 1 204 GLY 204 204 204 GLY GLY B . n 
B 1 205 THR 205 205 205 THR THR B . n 
B 1 206 CYS 206 206 206 CYS CYS B . n 
B 1 207 PHE 207 207 207 PHE PHE B . n 
B 1 208 TYR 208 208 208 TYR TYR B . n 
B 1 209 PHE 209 209 209 PHE PHE B . n 
B 1 210 GLY 210 210 210 GLY GLY B . n 
B 1 211 GLU 211 211 211 GLU GLU B . n 
B 1 212 LEU 212 212 212 LEU LEU B . n 
B 1 213 PRO 213 213 213 PRO PRO B . n 
B 1 214 LEU 214 214 214 LEU LEU B . n 
B 1 215 SER 215 215 215 SER SER B . n 
B 1 216 LEU 216 216 216 LEU LEU B . n 
B 1 217 ALA 217 217 217 ALA ALA B . n 
B 1 218 ALA 218 218 218 ALA ALA B . n 
B 1 219 CYS 219 219 219 CYS CYS B . n 
B 1 220 THR 220 220 220 THR THR B . n 
B 1 221 LYS 221 221 221 LYS LYS B . n 
B 1 222 GLN 222 222 222 GLN GLN B . n 
B 1 223 TRP 223 223 223 TRP TRP B . n 
B 1 224 ASP 224 224 224 ASP ASP B . n 
B 1 225 VAL 225 225 225 VAL VAL B . n 
B 1 226 VAL 226 226 226 VAL VAL B . n 
B 1 227 THR 227 227 227 THR THR B . n 
B 1 228 TYR 228 228 228 TYR TYR B . n 
B 1 229 LEU 229 229 229 LEU LEU B . n 
B 1 230 LEU 230 230 230 LEU LEU B . n 
B 1 231 GLU 231 231 231 GLU GLU B . n 
B 1 232 ASN 232 232 232 ASN ASN B . n 
B 1 233 PRO 233 233 233 PRO PRO B . n 
B 1 234 HIS 234 234 234 HIS HIS B . n 
B 1 235 GLN 235 235 235 GLN GLN B . n 
B 1 236 PRO 236 236 236 PRO PRO B . n 
B 1 237 ALA 237 237 237 ALA ALA B . n 
B 1 238 SER 238 238 238 SER SER B . n 
B 1 239 LEU 239 239 239 LEU LEU B . n 
B 1 240 GLU 240 240 240 GLU GLU B . n 
B 1 241 ALA 241 241 241 ALA ALA B . n 
B 1 242 THR 242 242 242 THR THR B . n 
B 1 243 ASP 243 243 243 ASP ASP B . n 
B 1 244 SER 244 244 244 SER SER B . n 
B 1 245 LEU 245 245 245 LEU LEU B . n 
B 1 246 GLY 246 246 246 GLY GLY B . n 
B 1 247 ASN 247 247 247 ASN ASN B . n 
B 1 248 THR 248 248 248 THR THR B . n 
B 1 249 VAL 249 249 249 VAL VAL B . n 
B 1 250 LEU 250 250 250 LEU LEU B . n 
B 1 251 HIS 251 251 251 HIS HIS B . n 
B 1 252 ALA 252 252 252 ALA ALA B . n 
B 1 253 LEU 253 253 253 LEU LEU B . n 
B 1 254 VAL 254 254 254 VAL VAL B . n 
B 1 255 MET 255 255 255 MET MET B . n 
B 1 256 ILE 256 256 256 ILE ILE B . n 
B 1 257 ALA 257 257 257 ALA ALA B . n 
B 1 258 ASP 258 258 258 ASP ASP B . n 
B 1 259 ASN 259 259 259 ASN ASN B . n 
B 1 260 SER 260 260 260 SER SER B . n 
B 1 261 PRO 261 261 261 PRO PRO B . n 
B 1 262 GLU 262 262 262 GLU GLU B . n 
B 1 263 ASN 263 263 263 ASN ASN B . n 
B 1 264 SER 264 264 264 SER SER B . n 
B 1 265 ALA 265 265 265 ALA ALA B . n 
B 1 266 LEU 266 266 266 LEU LEU B . n 
B 1 267 VAL 267 267 267 VAL VAL B . n 
B 1 268 ILE 268 268 268 ILE ILE B . n 
B 1 269 HIS 269 269 269 HIS HIS B . n 
B 1 270 MET 270 270 270 MET MET B . n 
B 1 271 TYR 271 271 271 TYR TYR B . n 
B 1 272 ASP 272 272 272 ASP ASP B . n 
B 1 273 GLY 273 273 273 GLY GLY B . n 
B 1 274 LEU 274 274 274 LEU LEU B . n 
B 1 275 LEU 275 275 275 LEU LEU B . n 
B 1 276 GLN 276 276 276 GLN GLN B . n 
B 1 277 MET 277 277 277 MET MET B . n 
B 1 278 GLY 278 278 278 GLY GLY B . n 
B 1 279 ALA 279 279 279 ALA ALA B . n 
B 1 280 ARG 280 280 280 ARG ARG B . n 
B 1 281 LEU 281 281 281 LEU LEU B . n 
B 1 282 CYS 282 282 282 CYS CYS B . n 
B 1 283 PRO 283 283 283 PRO PRO B . n 
B 1 284 THR 284 284 284 THR THR B . n 
B 1 285 VAL 285 285 285 VAL VAL B . n 
B 1 286 GLN 286 286 286 GLN GLN B . n 
B 1 287 LEU 287 287 287 LEU LEU B . n 
B 1 288 GLU 288 288 288 GLU GLU B . n 
B 1 289 GLU 289 289 289 GLU GLU B . n 
B 1 290 ILE 290 290 290 ILE ILE B . n 
B 1 291 SER 291 291 291 SER SER B . n 
B 1 292 ASN 292 292 292 ASN ASN B . n 
B 1 293 HIS 293 293 293 HIS HIS B . n 
B 1 294 GLN 294 294 294 GLN GLN B . n 
B 1 295 GLY 295 295 295 GLY GLY B . n 
B 1 296 LEU 296 296 296 LEU LEU B . n 
B 1 297 THR 297 297 297 THR THR B . n 
B 1 298 PRO 298 298 298 PRO PRO B . n 
B 1 299 LEU 299 299 299 LEU LEU B . n 
B 1 300 LYS 300 300 300 LYS LYS B . n 
B 1 301 LEU 301 301 301 LEU LEU B . n 
B 1 302 ALA 302 302 302 ALA ALA B . n 
B 1 303 ALA 303 303 303 ALA ALA B . n 
B 1 304 LYS 304 304 304 LYS LYS B . n 
B 1 305 GLU 305 305 305 GLU GLU B . n 
B 1 306 GLY 306 306 306 GLY GLY B . n 
B 1 307 LYS 307 307 307 LYS LYS B . n 
B 1 308 ILE 308 308 308 ILE ILE B . n 
B 1 309 GLU 309 309 309 GLU GLU B . n 
B 1 310 ILE 310 310 310 ILE ILE B . n 
B 1 311 PHE 311 311 311 PHE PHE B . n 
B 1 312 ARG 312 312 312 ARG ARG B . n 
B 1 313 HIS 313 313 313 HIS HIS B . n 
B 1 314 ILE 314 314 314 ILE ILE B . n 
B 1 315 LEU 315 315 315 LEU LEU B . n 
B 1 316 GLN 316 316 316 GLN GLN B . n 
B 1 317 ARG 317 317 317 ARG ARG B . n 
B 1 318 GLU 318 318 318 GLU GLU B . n 
B 1 319 PHE 319 319 319 PHE PHE B . n 
B 1 320 SER 320 320 320 SER SER B . n 
B 1 321 GLY 321 321 321 GLY GLY B . n 
B 1 322 PRO 322 322 322 PRO PRO B . n 
B 1 323 TYR 323 323 323 TYR TYR B . n 
B 1 324 GLN 324 324 324 GLN GLN B . n 
B 1 325 PRO 325 325 325 PRO PRO B . n 
B 1 326 LEU 326 326 326 LEU LEU B . n 
B 1 327 SER 327 327 327 SER SER B . n 
B 1 328 ARG 328 328 328 ARG ARG B . n 
B 1 329 LYS 329 329 329 LYS LYS B . n 
B 1 330 PHE 330 330 330 PHE PHE B . n 
B 1 331 THR 331 331 331 THR THR B . n 
B 1 332 GLU 332 332 332 GLU GLU B . n 
B 1 333 TRP 333 333 333 TRP TRP B . n 
B 1 334 CYS 334 334 334 CYS CYS B . n 
B 1 335 TYR 335 335 335 TYR TYR B . n 
B 1 336 GLY 336 336 336 GLY GLY B . n 
B 1 337 PRO 337 337 337 PRO PRO B . n 
B 1 338 VAL 338 338 338 VAL VAL B . n 
B 1 339 ARG 339 339 339 ARG ARG B . n 
B 1 340 VAL 340 340 340 VAL VAL B . n 
B 1 341 SER 341 341 341 SER SER B . n 
B 1 342 LEU 342 342 342 LEU LEU B . n 
B 1 343 TYR 343 343 343 TYR TYR B . n 
B 1 344 ASP 344 344 344 ASP ASP B . n 
B 1 345 LEU 345 345 345 LEU LEU B . n 
B 1 346 SER 346 346 346 SER SER B . n 
B 1 347 SER 347 347 347 SER SER B . n 
B 1 348 VAL 348 348 348 VAL VAL B . n 
B 1 349 ASP 349 349 349 ASP ASP B . n 
B 1 350 SER 350 350 350 SER SER B . n 
B 1 351 TRP 351 351 351 TRP TRP B . n 
B 1 352 GLU 352 352 352 GLU GLU B . n 
B 1 353 LYS 353 353 353 LYS LYS B . n 
B 1 354 ASN 354 354 354 ASN ASN B . n 
B 1 355 SER 355 355 355 SER SER B . n 
B 1 356 VAL 356 356 356 VAL VAL B . n 
B 1 357 LEU 357 357 357 LEU LEU B . n 
B 1 358 GLU 358 358 358 GLU GLU B . n 
B 1 359 ILE 359 359 359 ILE ILE B . n 
B 1 360 ILE 360 360 360 ILE ILE B . n 
B 1 361 ALA 361 361 361 ALA ALA B . n 
B 1 362 PHE 362 362 362 PHE PHE B . n 
B 1 363 HIS 363 363 363 HIS HIS B . n 
B 1 364 CYS 364 364 364 CYS CYS B . n 
B 1 365 LYS 365 365 365 LYS LYS B . n 
B 1 366 SER 366 366 366 SER SER B . n 
B 1 367 PRO 367 367 367 PRO PRO B . n 
B 1 368 ASN 368 368 368 ASN ASN B . n 
B 1 369 ARG 369 369 369 ARG ARG B . n 
B 1 370 HIS 370 370 370 HIS HIS B . n 
B 1 371 ARG 371 371 371 ARG ARG B . n 
B 1 372 MET 372 372 372 MET MET B . n 
B 1 373 VAL 373 373 373 VAL VAL B . n 
B 1 374 VAL 374 374 374 VAL VAL B . n 
B 1 375 LEU 375 375 375 LEU LEU B . n 
B 1 376 GLU 376 376 376 GLU GLU B . n 
B 1 377 PRO 377 377 377 PRO PRO B . n 
B 1 378 LEU 378 378 378 LEU LEU B . n 
B 1 379 ASN 379 379 379 ASN ASN B . n 
B 1 380 LYS 380 380 380 LYS LYS B . n 
B 1 381 LEU 381 381 381 LEU LEU B . n 
B 1 382 LEU 382 382 382 LEU LEU B . n 
B 1 383 GLN 383 383 383 GLN GLN B . n 
B 1 384 GLU 384 384 384 GLU GLU B . n 
B 1 385 LYS 385 385 385 LYS LYS B . n 
B 1 386 TRP 386 386 386 TRP TRP B . n 
B 1 387 ASP 387 387 387 ASP ASP B . n 
B 1 388 ARG 388 388 388 ARG ARG B . n 
B 1 389 LEU 389 389 389 LEU LEU B . n 
B 1 390 VAL 390 390 390 VAL VAL B . n 
B 1 391 SER 391 391 391 SER SER B . n 
B 1 392 ARG 392 392 392 ARG ARG B . n 
B 1 393 PHE 393 393 393 PHE PHE B . n 
B 1 394 PHE 394 394 394 PHE PHE B . n 
B 1 395 PHE 395 395 395 PHE PHE B . n 
B 1 396 ASN 396 396 396 ASN ASN B . n 
B 1 397 PHE 397 397 397 PHE PHE B . n 
B 1 398 ALA 398 398 398 ALA ALA B . n 
B 1 399 CYS 399 399 399 CYS CYS B . n 
B 1 400 TYR 400 400 400 TYR TYR B . n 
B 1 401 LEU 401 401 401 LEU LEU B . n 
B 1 402 VAL 402 402 402 VAL VAL B . n 
B 1 403 TYR 403 403 403 TYR TYR B . n 
B 1 404 MET 404 404 404 MET MET B . n 
B 1 405 PHE 405 405 405 PHE PHE B . n 
B 1 406 ILE 406 406 406 ILE ILE B . n 
B 1 407 PHE 407 407 407 PHE PHE B . n 
B 1 408 THR 408 408 408 THR THR B . n 
B 1 409 VAL 409 409 409 VAL VAL B . n 
B 1 410 VAL 410 410 410 VAL VAL B . n 
B 1 411 ALA 411 411 411 ALA ALA B . n 
B 1 412 TYR 412 412 412 TYR TYR B . n 
B 1 413 HIS 413 413 413 HIS HIS B . n 
B 1 414 GLN 414 414 414 GLN GLN B . n 
B 1 415 PRO 415 415 415 PRO PRO B . n 
B 1 416 SER 416 416 416 SER SER B . n 
B 1 417 LEU 417 417 417 LEU LEU B . n 
B 1 418 ASP 418 418 ?   ?   ?   B . n 
B 1 419 GLN 419 419 ?   ?   ?   B . n 
B 1 420 PRO 420 420 ?   ?   ?   B . n 
B 1 421 ALA 421 421 ?   ?   ?   B . n 
B 1 422 ILE 422 422 ?   ?   ?   B . n 
B 1 423 PRO 423 423 ?   ?   ?   B . n 
B 1 424 SER 424 424 ?   ?   ?   B . n 
B 1 425 SER 425 425 ?   ?   ?   B . n 
B 1 426 LYS 426 426 ?   ?   ?   B . n 
B 1 427 ALA 427 427 ?   ?   ?   B . n 
B 1 428 THR 428 428 ?   ?   ?   B . n 
B 1 429 PHE 429 429 429 PHE PHE B . n 
B 1 430 GLY 430 430 430 GLY GLY B . n 
B 1 431 GLU 431 431 431 GLU GLU B . n 
B 1 432 SER 432 432 432 SER SER B . n 
B 1 433 MET 433 433 433 MET MET B . n 
B 1 434 LEU 434 434 434 LEU LEU B . n 
B 1 435 LEU 435 435 435 LEU LEU B . n 
B 1 436 LEU 436 436 436 LEU LEU B . n 
B 1 437 GLY 437 437 437 GLY GLY B . n 
B 1 438 HIS 438 438 438 HIS HIS B . n 
B 1 439 ILE 439 439 439 ILE ILE B . n 
B 1 440 LEU 440 440 440 LEU LEU B . n 
B 1 441 ILE 441 441 441 ILE ILE B . n 
B 1 442 LEU 442 442 442 LEU LEU B . n 
B 1 443 LEU 443 443 443 LEU LEU B . n 
B 1 444 GLY 444 444 444 GLY GLY B . n 
B 1 445 GLY 445 445 445 GLY GLY B . n 
B 1 446 ILE 446 446 446 ILE ILE B . n 
B 1 447 TYR 447 447 447 TYR TYR B . n 
B 1 448 LEU 448 448 448 LEU LEU B . n 
B 1 449 LEU 449 449 449 LEU LEU B . n 
B 1 450 LEU 450 450 450 LEU LEU B . n 
B 1 451 GLY 451 451 451 GLY GLY B . n 
B 1 452 GLN 452 452 452 GLN GLN B . n 
B 1 453 LEU 453 453 453 LEU LEU B . n 
B 1 454 TRP 454 454 454 TRP TRP B . n 
B 1 455 TYR 455 455 455 TYR TYR B . n 
B 1 456 PHE 456 456 456 PHE PHE B . n 
B 1 457 TRP 457 457 457 TRP TRP B . n 
B 1 458 ARG 458 458 458 ARG ARG B . n 
B 1 459 ARG 459 459 459 ARG ARG B . n 
B 1 460 ARG 460 460 460 ARG ARG B . n 
B 1 461 LEU 461 461 461 LEU LEU B . n 
B 1 462 PHE 462 462 462 PHE PHE B . n 
B 1 463 ILE 463 463 463 ILE ILE B . n 
B 1 464 TRP 464 464 464 TRP TRP B . n 
B 1 465 ILE 465 465 465 ILE ILE B . n 
B 1 466 SER 466 466 466 SER SER B . n 
B 1 467 PHE 467 467 467 PHE PHE B . n 
B 1 468 MET 468 468 468 MET MET B . n 
B 1 469 ASP 469 469 469 ASP ASP B . n 
B 1 470 SER 470 470 470 SER SER B . n 
B 1 471 TYR 471 471 471 TYR TYR B . n 
B 1 472 PHE 472 472 472 PHE PHE B . n 
B 1 473 GLU 473 473 473 GLU GLU B . n 
B 1 474 ILE 474 474 474 ILE ILE B . n 
B 1 475 LEU 475 475 475 LEU LEU B . n 
B 1 476 PHE 476 476 476 PHE PHE B . n 
B 1 477 LEU 477 477 477 LEU LEU B . n 
B 1 478 LEU 478 478 478 LEU LEU B . n 
B 1 479 GLN 479 479 479 GLN GLN B . n 
B 1 480 ALA 480 480 480 ALA ALA B . n 
B 1 481 LEU 481 481 481 LEU LEU B . n 
B 1 482 LEU 482 482 482 LEU LEU B . n 
B 1 483 THR 483 483 483 THR THR B . n 
B 1 484 VAL 484 484 484 VAL VAL B . n 
B 1 485 LEU 485 485 485 LEU LEU B . n 
B 1 486 SER 486 486 486 SER SER B . n 
B 1 487 GLN 487 487 487 GLN GLN B . n 
B 1 488 VAL 488 488 488 VAL VAL B . n 
B 1 489 LEU 489 489 489 LEU LEU B . n 
B 1 490 ARG 490 490 490 ARG ARG B . n 
B 1 491 PHE 491 491 491 PHE PHE B . n 
B 1 492 MET 492 492 492 MET MET B . n 
B 1 493 GLU 493 493 493 GLU GLU B . n 
B 1 494 THR 494 494 494 THR THR B . n 
B 1 495 GLU 495 495 495 GLU GLU B . n 
B 1 496 TRP 496 496 496 TRP TRP B . n 
B 1 497 TYR 497 497 497 TYR TYR B . n 
B 1 498 LEU 498 498 498 LEU LEU B . n 
B 1 499 PRO 499 499 499 PRO PRO B . n 
B 1 500 LEU 500 500 500 LEU LEU B . n 
B 1 501 LEU 501 501 501 LEU LEU B . n 
B 1 502 VAL 502 502 502 VAL VAL B . n 
B 1 503 LEU 503 503 503 LEU LEU B . n 
B 1 504 SER 504 504 504 SER SER B . n 
B 1 505 LEU 505 505 505 LEU LEU B . n 
B 1 506 VAL 506 506 506 VAL VAL B . n 
B 1 507 LEU 507 507 507 LEU LEU B . n 
B 1 508 GLY 508 508 508 GLY GLY B . n 
B 1 509 TRP 509 509 509 TRP TRP B . n 
B 1 510 LEU 510 510 510 LEU LEU B . n 
B 1 511 ASN 511 511 511 ASN ASN B . n 
B 1 512 LEU 512 512 512 LEU LEU B . n 
B 1 513 LEU 513 513 513 LEU LEU B . n 
B 1 514 TYR 514 514 514 TYR TYR B . n 
B 1 515 TYR 515 515 515 TYR TYR B . n 
B 1 516 THR 516 516 516 THR THR B . n 
B 1 517 ARG 517 517 517 ARG ARG B . n 
B 1 518 GLY 518 518 518 GLY GLY B . n 
B 1 519 PHE 519 519 519 PHE PHE B . n 
B 1 520 GLN 520 520 520 GLN GLN B . n 
B 1 521 HIS 521 521 521 HIS HIS B . n 
B 1 522 THR 522 522 522 THR THR B . n 
B 1 523 GLY 523 523 523 GLY GLY B . n 
B 1 524 ILE 524 524 524 ILE ILE B . n 
B 1 525 TYR 525 525 525 TYR TYR B . n 
B 1 526 SER 526 526 526 SER SER B . n 
B 1 527 VAL 527 527 527 VAL VAL B . n 
B 1 528 MET 528 528 528 MET MET B . n 
B 1 529 ILE 529 529 529 ILE ILE B . n 
B 1 530 GLN 530 530 530 GLN GLN B . n 
B 1 531 LYS 531 531 531 LYS LYS B . n 
B 1 532 VAL 532 532 532 VAL VAL B . n 
B 1 533 ILE 533 533 533 ILE ILE B . n 
B 1 534 LEU 534 534 534 LEU LEU B . n 
B 1 535 ARG 535 535 535 ARG ARG B . n 
B 1 536 ASP 536 536 536 ASP ASP B . n 
B 1 537 LEU 537 537 537 LEU LEU B . n 
B 1 538 LEU 538 538 538 LEU LEU B . n 
B 1 539 ARG 539 539 539 ARG ARG B . n 
B 1 540 PHE 540 540 540 PHE PHE B . n 
B 1 541 LEU 541 541 541 LEU LEU B . n 
B 1 542 LEU 542 542 542 LEU LEU B . n 
B 1 543 VAL 543 543 543 VAL VAL B . n 
B 1 544 TYR 544 544 544 TYR TYR B . n 
B 1 545 LEU 545 545 545 LEU LEU B . n 
B 1 546 VAL 546 546 546 VAL VAL B . n 
B 1 547 PHE 547 547 547 PHE PHE B . n 
B 1 548 LEU 548 548 548 LEU LEU B . n 
B 1 549 PHE 549 549 549 PHE PHE B . n 
B 1 550 GLY 550 550 550 GLY GLY B . n 
B 1 551 PHE 551 551 551 PHE PHE B . n 
B 1 552 ALA 552 552 552 ALA ALA B . n 
B 1 553 VAL 553 553 553 VAL VAL B . n 
B 1 554 ALA 554 554 554 ALA ALA B . n 
B 1 555 LEU 555 555 555 LEU LEU B . n 
B 1 556 VAL 556 556 556 VAL VAL B . n 
B 1 557 SER 557 557 557 SER SER B . n 
B 1 558 LEU 558 558 558 LEU LEU B . n 
B 1 559 SER 559 559 559 SER SER B . n 
B 1 560 ARG 560 560 560 ARG ARG B . n 
B 1 561 GLU 561 561 561 GLU GLU B . n 
B 1 562 ALA 562 562 562 ALA ALA B . n 
B 1 563 ARG 563 563 563 ARG ARG B . n 
B 1 564 SER 564 564 ?   ?   ?   B . n 
B 1 565 PRO 565 565 ?   ?   ?   B . n 
B 1 566 LYS 566 566 ?   ?   ?   B . n 
B 1 567 ALA 567 567 ?   ?   ?   B . n 
B 1 568 PRO 568 568 ?   ?   ?   B . n 
B 1 569 GLU 569 569 ?   ?   ?   B . n 
B 1 570 ASP 570 570 ?   ?   ?   B . n 
B 1 571 ASN 571 571 ?   ?   ?   B . n 
B 1 572 ASN 572 572 ?   ?   ?   B . n 
B 1 573 SER 573 573 ?   ?   ?   B . n 
B 1 574 THR 574 574 ?   ?   ?   B . n 
B 1 575 VAL 575 575 ?   ?   ?   B . n 
B 1 576 THR 576 576 ?   ?   ?   B . n 
B 1 577 GLU 577 577 ?   ?   ?   B . n 
B 1 578 GLN 578 578 ?   ?   ?   B . n 
B 1 579 PRO 579 579 ?   ?   ?   B . n 
B 1 580 THR 580 580 ?   ?   ?   B . n 
B 1 581 VAL 581 581 ?   ?   ?   B . n 
B 1 582 GLY 582 582 ?   ?   ?   B . n 
B 1 583 GLN 583 583 ?   ?   ?   B . n 
B 1 584 GLU 584 584 ?   ?   ?   B . n 
B 1 585 GLU 585 585 ?   ?   ?   B . n 
B 1 586 GLU 586 586 ?   ?   ?   B . n 
B 1 587 PRO 587 587 ?   ?   ?   B . n 
B 1 588 ALA 588 588 ?   ?   ?   B . n 
B 1 589 PRO 589 589 589 PRO PRO B . n 
B 1 590 TYR 590 590 590 TYR TYR B . n 
B 1 591 ARG 591 591 591 ARG ARG B . n 
B 1 592 SER 592 592 592 SER SER B . n 
B 1 593 ILE 593 593 593 ILE ILE B . n 
B 1 594 LEU 594 594 594 LEU LEU B . n 
B 1 595 ASP 595 595 595 ASP ASP B . n 
B 1 596 ALA 596 596 596 ALA ALA B . n 
B 1 597 SER 597 597 597 SER SER B . n 
B 1 598 LEU 598 598 598 LEU LEU B . n 
B 1 599 GLU 599 599 599 GLU GLU B . n 
B 1 600 LEU 600 600 600 LEU LEU B . n 
B 1 601 PHE 601 601 601 PHE PHE B . n 
B 1 602 LYS 602 602 602 LYS LYS B . n 
B 1 603 PHE 603 603 603 PHE PHE B . n 
B 1 604 THR 604 604 604 THR THR B . n 
B 1 605 ILE 605 605 605 ILE ILE B . n 
B 1 606 GLY 606 606 606 GLY GLY B . n 
B 1 607 MET 607 607 607 MET MET B . n 
B 1 608 GLY 608 608 608 GLY GLY B . n 
B 1 609 GLU 609 609 609 GLU GLU B . n 
B 1 610 LEU 610 610 610 LEU LEU B . n 
B 1 611 ALA 611 611 611 ALA ALA B . n 
B 1 612 PHE 612 612 612 PHE PHE B . n 
B 1 613 GLN 613 613 613 GLN GLN B . n 
B 1 614 GLU 614 614 614 GLU GLU B . n 
B 1 615 GLN 615 615 615 GLN GLN B . n 
B 1 616 LEU 616 616 616 LEU LEU B . n 
B 1 617 ARG 617 617 617 ARG ARG B . n 
B 1 618 PHE 618 618 618 PHE PHE B . n 
B 1 619 ARG 619 619 619 ARG ARG B . n 
B 1 620 GLY 620 620 620 GLY GLY B . n 
B 1 621 VAL 621 621 621 VAL VAL B . n 
B 1 622 VAL 622 622 622 VAL VAL B . n 
B 1 623 LEU 623 623 623 LEU LEU B . n 
B 1 624 LEU 624 624 624 LEU LEU B . n 
B 1 625 LEU 625 625 625 LEU LEU B . n 
B 1 626 LEU 626 626 626 LEU LEU B . n 
B 1 627 LEU 627 627 627 LEU LEU B . n 
B 1 628 ALA 628 628 628 ALA ALA B . n 
B 1 629 TYR 629 629 629 TYR TYR B . n 
B 1 630 VAL 630 630 630 VAL VAL B . n 
B 1 631 LEU 631 631 631 LEU LEU B . n 
B 1 632 LEU 632 632 632 LEU LEU B . n 
B 1 633 THR 633 633 633 THR THR B . n 
B 1 634 TYR 634 634 634 TYR TYR B . n 
B 1 635 VAL 635 635 635 VAL VAL B . n 
B 1 636 LEU 636 636 636 LEU LEU B . n 
B 1 637 LEU 637 637 637 LEU LEU B . n 
B 1 638 LEU 638 638 638 LEU LEU B . n 
B 1 639 ASN 639 639 639 ASN ASN B . n 
B 1 640 MET 640 640 640 MET MET B . n 
B 1 641 LEU 641 641 641 LEU LEU B . n 
B 1 642 ILE 642 642 642 ILE ILE B . n 
B 1 643 ALA 643 643 643 ALA ALA B . n 
B 1 644 LEU 644 644 644 LEU LEU B . n 
B 1 645 MET 645 645 645 MET MET B . n 
B 1 646 SER 646 646 646 SER SER B . n 
B 1 647 GLU 647 647 647 GLU GLU B . n 
B 1 648 THR 648 648 648 THR THR B . n 
B 1 649 VAL 649 649 649 VAL VAL B . n 
B 1 650 ASN 650 650 650 ASN ASN B . n 
B 1 651 HIS 651 651 651 HIS HIS B . n 
B 1 652 VAL 652 652 652 VAL VAL B . n 
B 1 653 ALA 653 653 653 ALA ALA B . n 
B 1 654 ASP 654 654 654 ASP ASP B . n 
B 1 655 ASN 655 655 655 ASN ASN B . n 
B 1 656 SER 656 656 656 SER SER B . n 
B 1 657 TRP 657 657 657 TRP TRP B . n 
B 1 658 SER 658 658 658 SER SER B . n 
B 1 659 ILE 659 659 659 ILE ILE B . n 
B 1 660 TRP 660 660 660 TRP TRP B . n 
B 1 661 LYS 661 661 661 LYS LYS B . n 
B 1 662 LEU 662 662 662 LEU LEU B . n 
B 1 663 GLN 663 663 663 GLN GLN B . n 
B 1 664 LYS 664 664 664 LYS LYS B . n 
B 1 665 ALA 665 665 665 ALA ALA B . n 
B 1 666 ILE 666 666 666 ILE ILE B . n 
B 1 667 SER 667 667 667 SER SER B . n 
B 1 668 VAL 668 668 668 VAL VAL B . n 
B 1 669 LEU 669 669 669 LEU LEU B . n 
B 1 670 GLU 670 670 670 GLU GLU B . n 
B 1 671 MET 671 671 671 MET MET B . n 
B 1 672 GLU 672 672 672 GLU GLU B . n 
B 1 673 ASN 673 673 673 ASN ASN B . n 
B 1 674 GLY 674 674 674 GLY GLY B . n 
B 1 675 TYR 675 675 675 TYR TYR B . n 
B 1 676 TRP 676 676 676 TRP TRP B . n 
B 1 677 TRP 677 677 677 TRP TRP B . n 
B 1 678 CYS 678 678 678 CYS CYS B . n 
B 1 679 ARG 679 679 679 ARG ARG B . n 
B 1 680 ARG 680 680 680 ARG ARG B . n 
B 1 681 LYS 681 681 681 LYS LYS B . n 
B 1 682 LYS 682 682 682 LYS LYS B . n 
B 1 683 HIS 683 683 683 HIS HIS B . n 
B 1 684 ARG 684 684 684 ARG ARG B . n 
B 1 685 GLU 685 685 685 GLU GLU B . n 
B 1 686 GLY 686 686 686 GLY GLY B . n 
B 1 687 ARG 687 687 687 ARG ARG B . n 
B 1 688 LEU 688 688 688 LEU LEU B . n 
B 1 689 LEU 689 689 689 LEU LEU B . n 
B 1 690 LYS 690 690 690 LYS LYS B . n 
B 1 691 VAL 691 691 691 VAL VAL B . n 
B 1 692 GLY 692 692 692 GLY GLY B . n 
B 1 693 THR 693 693 693 THR THR B . n 
B 1 694 ARG 694 694 694 ARG ARG B . n 
B 1 695 GLY 695 695 695 GLY GLY B . n 
B 1 696 ASP 696 696 ?   ?   ?   B . n 
B 1 697 GLY 697 697 ?   ?   ?   B . n 
B 1 698 THR 698 698 ?   ?   ?   B . n 
B 1 699 PRO 699 699 699 PRO PRO B . n 
B 1 700 ASP 700 700 700 ASP ASP B . n 
B 1 701 GLU 701 701 701 GLU GLU B . n 
B 1 702 ARG 702 702 702 ARG ARG B . n 
B 1 703 TRP 703 703 703 TRP TRP B . n 
B 1 704 CYS 704 704 704 CYS CYS B . n 
B 1 705 PHE 705 705 705 PHE PHE B . n 
B 1 706 ARG 706 706 706 ARG ARG B . n 
B 1 707 VAL 707 707 707 VAL VAL B . n 
B 1 708 GLU 708 708 708 GLU GLU B . n 
B 1 709 GLU 709 709 709 GLU GLU B . n 
B 1 710 VAL 710 710 710 VAL VAL B . n 
B 1 711 ASN 711 711 711 ASN ASN B . n 
B 1 712 TRP 712 712 712 TRP TRP B . n 
B 1 713 ALA 713 713 713 ALA ALA B . n 
B 1 714 ALA 714 714 714 ALA ALA B . n 
B 1 715 TRP 715 715 715 TRP TRP B . n 
B 1 716 GLU 716 716 716 GLU GLU B . n 
B 1 717 LYS 717 717 717 LYS LYS B . n 
B 1 718 THR 718 718 718 THR THR B . n 
B 1 719 LEU 719 719 719 LEU LEU B . n 
B 1 720 PRO 720 720 ?   ?   ?   B . n 
B 1 721 THR 721 721 ?   ?   ?   B . n 
B 1 722 LEU 722 722 ?   ?   ?   B . n 
B 1 723 SER 723 723 ?   ?   ?   B . n 
B 1 724 GLU 724 724 ?   ?   ?   B . n 
B 1 725 ASP 725 725 ?   ?   ?   B . n 
B 1 726 PRO 726 726 ?   ?   ?   B . n 
B 1 727 SER 727 727 ?   ?   ?   B . n 
B 1 728 GLY 728 728 ?   ?   ?   B . n 
B 1 729 PRO 729 729 ?   ?   ?   B . n 
B 1 730 GLY 730 730 ?   ?   ?   B . n 
B 1 731 ILE 731 731 ?   ?   ?   B . n 
B 1 732 THR 732 732 ?   ?   ?   B . n 
B 1 733 GLY 733 733 ?   ?   ?   B . n 
B 1 734 ASN 734 734 ?   ?   ?   B . n 
B 1 735 LYS 735 735 ?   ?   ?   B . n 
B 1 736 LYS 736 736 ?   ?   ?   B . n 
B 1 737 ASN 737 737 ?   ?   ?   B . n 
B 1 738 PRO 738 738 ?   ?   ?   B . n 
B 1 739 THR 739 739 ?   ?   ?   B . n 
B 1 740 SER 740 740 ?   ?   ?   B . n 
B 1 741 LYS 741 741 ?   ?   ?   B . n 
B 1 742 PRO 742 742 ?   ?   ?   B . n 
B 1 743 GLY 743 743 ?   ?   ?   B . n 
B 1 744 LYS 744 744 ?   ?   ?   B . n 
B 1 745 ASN 745 745 ?   ?   ?   B . n 
B 1 746 SER 746 746 ?   ?   ?   B . n 
B 1 747 ALA 747 747 ?   ?   ?   B . n 
B 1 748 SER 748 748 ?   ?   ?   B . n 
B 1 749 GLU 749 749 ?   ?   ?   B . n 
B 1 750 GLU 750 750 ?   ?   ?   B . n 
B 1 751 ASP 751 751 ?   ?   ?   B . n 
B 1 752 HIS 752 752 ?   ?   ?   B . n 
B 1 753 LEU 753 753 ?   ?   ?   B . n 
B 1 754 PRO 754 754 ?   ?   ?   B . n 
B 1 755 LEU 755 755 ?   ?   ?   B . n 
B 1 756 GLN 756 756 ?   ?   ?   B . n 
B 1 757 VAL 757 757 ?   ?   ?   B . n 
B 1 758 LEU 758 758 ?   ?   ?   B . n 
B 1 759 GLN 759 759 ?   ?   ?   B . n 
B 1 760 SER 760 760 ?   ?   ?   B . n 
B 1 761 PRO 761 761 ?   ?   ?   B . n 
C 1 1   MET 1   1   ?   ?   ?   C . n 
C 1 2   THR 2   2   ?   ?   ?   C . n 
C 1 3   SER 3   3   ?   ?   ?   C . n 
C 1 4   ALA 4   4   ?   ?   ?   C . n 
C 1 5   SER 5   5   ?   ?   ?   C . n 
C 1 6   SER 6   6   ?   ?   ?   C . n 
C 1 7   PRO 7   7   ?   ?   ?   C . n 
C 1 8   PRO 8   8   ?   ?   ?   C . n 
C 1 9   ALA 9   9   ?   ?   ?   C . n 
C 1 10  PHE 10  10  ?   ?   ?   C . n 
C 1 11  ARG 11  11  ?   ?   ?   C . n 
C 1 12  LEU 12  12  ?   ?   ?   C . n 
C 1 13  GLU 13  13  ?   ?   ?   C . n 
C 1 14  THR 14  14  ?   ?   ?   C . n 
C 1 15  SER 15  15  ?   ?   ?   C . n 
C 1 16  ASP 16  16  ?   ?   ?   C . n 
C 1 17  GLY 17  17  ?   ?   ?   C . n 
C 1 18  ASP 18  18  ?   ?   ?   C . n 
C 1 19  GLU 19  19  ?   ?   ?   C . n 
C 1 20  GLU 20  20  ?   ?   ?   C . n 
C 1 21  GLY 21  21  ?   ?   ?   C . n 
C 1 22  ASN 22  22  ?   ?   ?   C . n 
C 1 23  ALA 23  23  ?   ?   ?   C . n 
C 1 24  GLU 24  24  ?   ?   ?   C . n 
C 1 25  VAL 25  25  ?   ?   ?   C . n 
C 1 26  ASN 26  26  ?   ?   ?   C . n 
C 1 27  LYS 27  27  ?   ?   ?   C . n 
C 1 28  GLY 28  28  ?   ?   ?   C . n 
C 1 29  LYS 29  29  ?   ?   ?   C . n 
C 1 30  GLN 30  30  ?   ?   ?   C . n 
C 1 31  GLU 31  31  ?   ?   ?   C . n 
C 1 32  PRO 32  32  ?   ?   ?   C . n 
C 1 33  PRO 33  33  ?   ?   ?   C . n 
C 1 34  PRO 34  34  ?   ?   ?   C . n 
C 1 35  MET 35  35  ?   ?   ?   C . n 
C 1 36  GLU 36  36  ?   ?   ?   C . n 
C 1 37  SER 37  37  ?   ?   ?   C . n 
C 1 38  PRO 38  38  ?   ?   ?   C . n 
C 1 39  PHE 39  39  ?   ?   ?   C . n 
C 1 40  GLN 40  40  ?   ?   ?   C . n 
C 1 41  ARG 41  41  ?   ?   ?   C . n 
C 1 42  GLU 42  42  ?   ?   ?   C . n 
C 1 43  ASP 43  43  ?   ?   ?   C . n 
C 1 44  ARG 44  44  ?   ?   ?   C . n 
C 1 45  ASN 45  45  ?   ?   ?   C . n 
C 1 46  SER 46  46  ?   ?   ?   C . n 
C 1 47  SER 47  47  ?   ?   ?   C . n 
C 1 48  PRO 48  48  ?   ?   ?   C . n 
C 1 49  GLN 49  49  ?   ?   ?   C . n 
C 1 50  ILE 50  50  ?   ?   ?   C . n 
C 1 51  LYS 51  51  ?   ?   ?   C . n 
C 1 52  VAL 52  52  ?   ?   ?   C . n 
C 1 53  ASN 53  53  ?   ?   ?   C . n 
C 1 54  LEU 54  54  ?   ?   ?   C . n 
C 1 55  ASN 55  55  ?   ?   ?   C . n 
C 1 56  PHE 56  56  ?   ?   ?   C . n 
C 1 57  ILE 57  57  ?   ?   ?   C . n 
C 1 58  LYS 58  58  ?   ?   ?   C . n 
C 1 59  ARG 59  59  ?   ?   ?   C . n 
C 1 60  PRO 60  60  ?   ?   ?   C . n 
C 1 61  PRO 61  61  ?   ?   ?   C . n 
C 1 62  LYS 62  62  ?   ?   ?   C . n 
C 1 63  ASN 63  63  ?   ?   ?   C . n 
C 1 64  THR 64  64  ?   ?   ?   C . n 
C 1 65  SER 65  65  ?   ?   ?   C . n 
C 1 66  ALA 66  66  ?   ?   ?   C . n 
C 1 67  PRO 67  67  ?   ?   ?   C . n 
C 1 68  SER 68  68  ?   ?   ?   C . n 
C 1 69  GLN 69  69  ?   ?   ?   C . n 
C 1 70  GLN 70  70  ?   ?   ?   C . n 
C 1 71  GLU 71  71  ?   ?   ?   C . n 
C 1 72  PRO 72  72  ?   ?   ?   C . n 
C 1 73  ASP 73  73  ?   ?   ?   C . n 
C 1 74  ARG 74  74  74  ARG ARG C . n 
C 1 75  PHE 75  75  75  PHE PHE C . n 
C 1 76  ASP 76  76  76  ASP ASP C . n 
C 1 77  ARG 77  77  77  ARG ARG C . n 
C 1 78  ASP 78  78  78  ASP ASP C . n 
C 1 79  ARG 79  79  79  ARG ARG C . n 
C 1 80  LEU 80  80  80  LEU LEU C . n 
C 1 81  PHE 81  81  81  PHE PHE C . n 
C 1 82  SER 82  82  82  SER SER C . n 
C 1 83  VAL 83  83  83  VAL VAL C . n 
C 1 84  VAL 84  84  84  VAL VAL C . n 
C 1 85  SER 85  85  85  SER SER C . n 
C 1 86  ARG 86  86  86  ARG ARG C . n 
C 1 87  GLY 87  87  87  GLY GLY C . n 
C 1 88  VAL 88  88  88  VAL VAL C . n 
C 1 89  PRO 89  89  89  PRO PRO C . n 
C 1 90  GLU 90  90  90  GLU GLU C . n 
C 1 91  GLU 91  91  91  GLU GLU C . n 
C 1 92  LEU 92  92  92  LEU LEU C . n 
C 1 93  THR 93  93  93  THR THR C . n 
C 1 94  GLY 94  94  94  GLY GLY C . n 
C 1 95  LEU 95  95  95  LEU LEU C . n 
C 1 96  LEU 96  96  96  LEU LEU C . n 
C 1 97  GLU 97  97  97  GLU GLU C . n 
C 1 98  TYR 98  98  98  TYR TYR C . n 
C 1 99  LEU 99  99  99  LEU LEU C . n 
C 1 100 ARG 100 100 100 ARG ARG C . n 
C 1 101 TRP 101 101 101 TRP TRP C . n 
C 1 102 ASN 102 102 102 ASN ASN C . n 
C 1 103 SER 103 103 103 SER SER C . n 
C 1 104 LYS 104 104 104 LYS LYS C . n 
C 1 105 TYR 105 105 105 TYR TYR C . n 
C 1 106 LEU 106 106 106 LEU LEU C . n 
C 1 107 THR 107 107 107 THR THR C . n 
C 1 108 ASP 108 108 108 ASP ASP C . n 
C 1 109 SER 109 109 109 SER SER C . n 
C 1 110 ALA 110 110 110 ALA ALA C . n 
C 1 111 TYR 111 111 111 TYR TYR C . n 
C 1 112 THR 112 112 112 THR THR C . n 
C 1 113 GLU 113 113 113 GLU GLU C . n 
C 1 114 GLY 114 114 114 GLY GLY C . n 
C 1 115 SER 115 115 115 SER SER C . n 
C 1 116 THR 116 116 116 THR THR C . n 
C 1 117 GLY 117 117 117 GLY GLY C . n 
C 1 118 LYS 118 118 118 LYS LYS C . n 
C 1 119 THR 119 119 119 THR THR C . n 
C 1 120 CYS 120 120 120 CYS CYS C . n 
C 1 121 LEU 121 121 121 LEU LEU C . n 
C 1 122 MET 122 122 122 MET MET C . n 
C 1 123 LYS 123 123 123 LYS LYS C . n 
C 1 124 ALA 124 124 124 ALA ALA C . n 
C 1 125 VAL 125 125 125 VAL VAL C . n 
C 1 126 LEU 126 126 126 LEU LEU C . n 
C 1 127 ASN 127 127 127 ASN ASN C . n 
C 1 128 LEU 128 128 128 LEU LEU C . n 
C 1 129 GLN 129 129 129 GLN GLN C . n 
C 1 130 ASP 130 130 130 ASP ASP C . n 
C 1 131 GLY 131 131 131 GLY GLY C . n 
C 1 132 VAL 132 132 132 VAL VAL C . n 
C 1 133 ASN 133 133 133 ASN ASN C . n 
C 1 134 ALA 134 134 134 ALA ALA C . n 
C 1 135 CYS 135 135 135 CYS CYS C . n 
C 1 136 ILE 136 136 136 ILE ILE C . n 
C 1 137 MET 137 137 137 MET MET C . n 
C 1 138 PRO 138 138 138 PRO PRO C . n 
C 1 139 LEU 139 139 139 LEU LEU C . n 
C 1 140 LEU 140 140 140 LEU LEU C . n 
C 1 141 GLN 141 141 141 GLN GLN C . n 
C 1 142 ILE 142 142 142 ILE ILE C . n 
C 1 143 ASP 143 143 143 ASP ASP C . n 
C 1 144 LYS 144 144 144 LYS LYS C . n 
C 1 145 ASP 145 145 145 ASP ASP C . n 
C 1 146 SER 146 146 146 SER SER C . n 
C 1 147 GLY 147 147 147 GLY GLY C . n 
C 1 148 ASN 148 148 148 ASN ASN C . n 
C 1 149 PRO 149 149 149 PRO PRO C . n 
C 1 150 LYS 150 150 150 LYS LYS C . n 
C 1 151 LEU 151 151 151 LEU LEU C . n 
C 1 152 LEU 152 152 152 LEU LEU C . n 
C 1 153 VAL 153 153 153 VAL VAL C . n 
C 1 154 ASN 154 154 154 ASN ASN C . n 
C 1 155 ALA 155 155 155 ALA ALA C . n 
C 1 156 GLN 156 156 156 GLN GLN C . n 
C 1 157 CYS 157 157 157 CYS CYS C . n 
C 1 158 THR 158 158 158 THR THR C . n 
C 1 159 ASP 159 159 159 ASP ASP C . n 
C 1 160 GLU 160 160 160 GLU GLU C . n 
C 1 161 PHE 161 161 161 PHE PHE C . n 
C 1 162 TYR 162 162 162 TYR TYR C . n 
C 1 163 GLN 163 163 163 GLN GLN C . n 
C 1 164 GLY 164 164 164 GLY GLY C . n 
C 1 165 HIS 165 165 165 HIS HIS C . n 
C 1 166 SER 166 166 166 SER SER C . n 
C 1 167 ALA 167 167 167 ALA ALA C . n 
C 1 168 LEU 168 168 168 LEU LEU C . n 
C 1 169 HIS 169 169 169 HIS HIS C . n 
C 1 170 ILE 170 170 170 ILE ILE C . n 
C 1 171 ALA 171 171 171 ALA ALA C . n 
C 1 172 ILE 172 172 172 ILE ILE C . n 
C 1 173 GLU 173 173 173 GLU GLU C . n 
C 1 174 LYS 174 174 174 LYS LYS C . n 
C 1 175 ARG 175 175 175 ARG ARG C . n 
C 1 176 SER 176 176 176 SER SER C . n 
C 1 177 LEU 177 177 177 LEU LEU C . n 
C 1 178 GLN 178 178 178 GLN GLN C . n 
C 1 179 CYS 179 179 179 CYS CYS C . n 
C 1 180 VAL 180 180 180 VAL VAL C . n 
C 1 181 LYS 181 181 181 LYS LYS C . n 
C 1 182 LEU 182 182 182 LEU LEU C . n 
C 1 183 LEU 183 183 183 LEU LEU C . n 
C 1 184 VAL 184 184 184 VAL VAL C . n 
C 1 185 GLU 185 185 185 GLU GLU C . n 
C 1 186 ASN 186 186 186 ASN ASN C . n 
C 1 187 GLY 187 187 187 GLY GLY C . n 
C 1 188 ALA 188 188 188 ALA ALA C . n 
C 1 189 ASP 189 189 189 ASP ASP C . n 
C 1 190 VAL 190 190 190 VAL VAL C . n 
C 1 191 HIS 191 191 191 HIS HIS C . n 
C 1 192 LEU 192 192 192 LEU LEU C . n 
C 1 193 ARG 193 193 193 ARG ARG C . n 
C 1 194 ALA 194 194 194 ALA ALA C . n 
C 1 195 CYS 195 195 195 CYS CYS C . n 
C 1 196 GLY 196 196 196 GLY GLY C . n 
C 1 197 ARG 197 197 197 ARG ARG C . n 
C 1 198 PHE 198 198 198 PHE PHE C . n 
C 1 199 PHE 199 199 199 PHE PHE C . n 
C 1 200 GLN 200 200 200 GLN GLN C . n 
C 1 201 LYS 201 201 201 LYS LYS C . n 
C 1 202 HIS 202 202 202 HIS HIS C . n 
C 1 203 GLN 203 203 203 GLN GLN C . n 
C 1 204 GLY 204 204 204 GLY GLY C . n 
C 1 205 THR 205 205 205 THR THR C . n 
C 1 206 CYS 206 206 206 CYS CYS C . n 
C 1 207 PHE 207 207 207 PHE PHE C . n 
C 1 208 TYR 208 208 208 TYR TYR C . n 
C 1 209 PHE 209 209 209 PHE PHE C . n 
C 1 210 GLY 210 210 210 GLY GLY C . n 
C 1 211 GLU 211 211 211 GLU GLU C . n 
C 1 212 LEU 212 212 212 LEU LEU C . n 
C 1 213 PRO 213 213 213 PRO PRO C . n 
C 1 214 LEU 214 214 214 LEU LEU C . n 
C 1 215 SER 215 215 215 SER SER C . n 
C 1 216 LEU 216 216 216 LEU LEU C . n 
C 1 217 ALA 217 217 217 ALA ALA C . n 
C 1 218 ALA 218 218 218 ALA ALA C . n 
C 1 219 CYS 219 219 219 CYS CYS C . n 
C 1 220 THR 220 220 220 THR THR C . n 
C 1 221 LYS 221 221 221 LYS LYS C . n 
C 1 222 GLN 222 222 222 GLN GLN C . n 
C 1 223 TRP 223 223 223 TRP TRP C . n 
C 1 224 ASP 224 224 224 ASP ASP C . n 
C 1 225 VAL 225 225 225 VAL VAL C . n 
C 1 226 VAL 226 226 226 VAL VAL C . n 
C 1 227 THR 227 227 227 THR THR C . n 
C 1 228 TYR 228 228 228 TYR TYR C . n 
C 1 229 LEU 229 229 229 LEU LEU C . n 
C 1 230 LEU 230 230 230 LEU LEU C . n 
C 1 231 GLU 231 231 231 GLU GLU C . n 
C 1 232 ASN 232 232 232 ASN ASN C . n 
C 1 233 PRO 233 233 233 PRO PRO C . n 
C 1 234 HIS 234 234 234 HIS HIS C . n 
C 1 235 GLN 235 235 235 GLN GLN C . n 
C 1 236 PRO 236 236 236 PRO PRO C . n 
C 1 237 ALA 237 237 237 ALA ALA C . n 
C 1 238 SER 238 238 238 SER SER C . n 
C 1 239 LEU 239 239 239 LEU LEU C . n 
C 1 240 GLU 240 240 240 GLU GLU C . n 
C 1 241 ALA 241 241 241 ALA ALA C . n 
C 1 242 THR 242 242 242 THR THR C . n 
C 1 243 ASP 243 243 243 ASP ASP C . n 
C 1 244 SER 244 244 244 SER SER C . n 
C 1 245 LEU 245 245 245 LEU LEU C . n 
C 1 246 GLY 246 246 246 GLY GLY C . n 
C 1 247 ASN 247 247 247 ASN ASN C . n 
C 1 248 THR 248 248 248 THR THR C . n 
C 1 249 VAL 249 249 249 VAL VAL C . n 
C 1 250 LEU 250 250 250 LEU LEU C . n 
C 1 251 HIS 251 251 251 HIS HIS C . n 
C 1 252 ALA 252 252 252 ALA ALA C . n 
C 1 253 LEU 253 253 253 LEU LEU C . n 
C 1 254 VAL 254 254 254 VAL VAL C . n 
C 1 255 MET 255 255 255 MET MET C . n 
C 1 256 ILE 256 256 256 ILE ILE C . n 
C 1 257 ALA 257 257 257 ALA ALA C . n 
C 1 258 ASP 258 258 258 ASP ASP C . n 
C 1 259 ASN 259 259 259 ASN ASN C . n 
C 1 260 SER 260 260 260 SER SER C . n 
C 1 261 PRO 261 261 261 PRO PRO C . n 
C 1 262 GLU 262 262 262 GLU GLU C . n 
C 1 263 ASN 263 263 263 ASN ASN C . n 
C 1 264 SER 264 264 264 SER SER C . n 
C 1 265 ALA 265 265 265 ALA ALA C . n 
C 1 266 LEU 266 266 266 LEU LEU C . n 
C 1 267 VAL 267 267 267 VAL VAL C . n 
C 1 268 ILE 268 268 268 ILE ILE C . n 
C 1 269 HIS 269 269 269 HIS HIS C . n 
C 1 270 MET 270 270 270 MET MET C . n 
C 1 271 TYR 271 271 271 TYR TYR C . n 
C 1 272 ASP 272 272 272 ASP ASP C . n 
C 1 273 GLY 273 273 273 GLY GLY C . n 
C 1 274 LEU 274 274 274 LEU LEU C . n 
C 1 275 LEU 275 275 275 LEU LEU C . n 
C 1 276 GLN 276 276 276 GLN GLN C . n 
C 1 277 MET 277 277 277 MET MET C . n 
C 1 278 GLY 278 278 278 GLY GLY C . n 
C 1 279 ALA 279 279 279 ALA ALA C . n 
C 1 280 ARG 280 280 280 ARG ARG C . n 
C 1 281 LEU 281 281 281 LEU LEU C . n 
C 1 282 CYS 282 282 282 CYS CYS C . n 
C 1 283 PRO 283 283 283 PRO PRO C . n 
C 1 284 THR 284 284 284 THR THR C . n 
C 1 285 VAL 285 285 285 VAL VAL C . n 
C 1 286 GLN 286 286 286 GLN GLN C . n 
C 1 287 LEU 287 287 287 LEU LEU C . n 
C 1 288 GLU 288 288 288 GLU GLU C . n 
C 1 289 GLU 289 289 289 GLU GLU C . n 
C 1 290 ILE 290 290 290 ILE ILE C . n 
C 1 291 SER 291 291 291 SER SER C . n 
C 1 292 ASN 292 292 292 ASN ASN C . n 
C 1 293 HIS 293 293 293 HIS HIS C . n 
C 1 294 GLN 294 294 294 GLN GLN C . n 
C 1 295 GLY 295 295 295 GLY GLY C . n 
C 1 296 LEU 296 296 296 LEU LEU C . n 
C 1 297 THR 297 297 297 THR THR C . n 
C 1 298 PRO 298 298 298 PRO PRO C . n 
C 1 299 LEU 299 299 299 LEU LEU C . n 
C 1 300 LYS 300 300 300 LYS LYS C . n 
C 1 301 LEU 301 301 301 LEU LEU C . n 
C 1 302 ALA 302 302 302 ALA ALA C . n 
C 1 303 ALA 303 303 303 ALA ALA C . n 
C 1 304 LYS 304 304 304 LYS LYS C . n 
C 1 305 GLU 305 305 305 GLU GLU C . n 
C 1 306 GLY 306 306 306 GLY GLY C . n 
C 1 307 LYS 307 307 307 LYS LYS C . n 
C 1 308 ILE 308 308 308 ILE ILE C . n 
C 1 309 GLU 309 309 309 GLU GLU C . n 
C 1 310 ILE 310 310 310 ILE ILE C . n 
C 1 311 PHE 311 311 311 PHE PHE C . n 
C 1 312 ARG 312 312 312 ARG ARG C . n 
C 1 313 HIS 313 313 313 HIS HIS C . n 
C 1 314 ILE 314 314 314 ILE ILE C . n 
C 1 315 LEU 315 315 315 LEU LEU C . n 
C 1 316 GLN 316 316 316 GLN GLN C . n 
C 1 317 ARG 317 317 317 ARG ARG C . n 
C 1 318 GLU 318 318 318 GLU GLU C . n 
C 1 319 PHE 319 319 319 PHE PHE C . n 
C 1 320 SER 320 320 320 SER SER C . n 
C 1 321 GLY 321 321 321 GLY GLY C . n 
C 1 322 PRO 322 322 322 PRO PRO C . n 
C 1 323 TYR 323 323 323 TYR TYR C . n 
C 1 324 GLN 324 324 324 GLN GLN C . n 
C 1 325 PRO 325 325 325 PRO PRO C . n 
C 1 326 LEU 326 326 326 LEU LEU C . n 
C 1 327 SER 327 327 327 SER SER C . n 
C 1 328 ARG 328 328 328 ARG ARG C . n 
C 1 329 LYS 329 329 329 LYS LYS C . n 
C 1 330 PHE 330 330 330 PHE PHE C . n 
C 1 331 THR 331 331 331 THR THR C . n 
C 1 332 GLU 332 332 332 GLU GLU C . n 
C 1 333 TRP 333 333 333 TRP TRP C . n 
C 1 334 CYS 334 334 334 CYS CYS C . n 
C 1 335 TYR 335 335 335 TYR TYR C . n 
C 1 336 GLY 336 336 336 GLY GLY C . n 
C 1 337 PRO 337 337 337 PRO PRO C . n 
C 1 338 VAL 338 338 338 VAL VAL C . n 
C 1 339 ARG 339 339 339 ARG ARG C . n 
C 1 340 VAL 340 340 340 VAL VAL C . n 
C 1 341 SER 341 341 341 SER SER C . n 
C 1 342 LEU 342 342 342 LEU LEU C . n 
C 1 343 TYR 343 343 343 TYR TYR C . n 
C 1 344 ASP 344 344 344 ASP ASP C . n 
C 1 345 LEU 345 345 345 LEU LEU C . n 
C 1 346 SER 346 346 346 SER SER C . n 
C 1 347 SER 347 347 347 SER SER C . n 
C 1 348 VAL 348 348 348 VAL VAL C . n 
C 1 349 ASP 349 349 349 ASP ASP C . n 
C 1 350 SER 350 350 350 SER SER C . n 
C 1 351 TRP 351 351 351 TRP TRP C . n 
C 1 352 GLU 352 352 352 GLU GLU C . n 
C 1 353 LYS 353 353 353 LYS LYS C . n 
C 1 354 ASN 354 354 354 ASN ASN C . n 
C 1 355 SER 355 355 355 SER SER C . n 
C 1 356 VAL 356 356 356 VAL VAL C . n 
C 1 357 LEU 357 357 357 LEU LEU C . n 
C 1 358 GLU 358 358 358 GLU GLU C . n 
C 1 359 ILE 359 359 359 ILE ILE C . n 
C 1 360 ILE 360 360 360 ILE ILE C . n 
C 1 361 ALA 361 361 361 ALA ALA C . n 
C 1 362 PHE 362 362 362 PHE PHE C . n 
C 1 363 HIS 363 363 363 HIS HIS C . n 
C 1 364 CYS 364 364 364 CYS CYS C . n 
C 1 365 LYS 365 365 365 LYS LYS C . n 
C 1 366 SER 366 366 366 SER SER C . n 
C 1 367 PRO 367 367 367 PRO PRO C . n 
C 1 368 ASN 368 368 368 ASN ASN C . n 
C 1 369 ARG 369 369 369 ARG ARG C . n 
C 1 370 HIS 370 370 370 HIS HIS C . n 
C 1 371 ARG 371 371 371 ARG ARG C . n 
C 1 372 MET 372 372 372 MET MET C . n 
C 1 373 VAL 373 373 373 VAL VAL C . n 
C 1 374 VAL 374 374 374 VAL VAL C . n 
C 1 375 LEU 375 375 375 LEU LEU C . n 
C 1 376 GLU 376 376 376 GLU GLU C . n 
C 1 377 PRO 377 377 377 PRO PRO C . n 
C 1 378 LEU 378 378 378 LEU LEU C . n 
C 1 379 ASN 379 379 379 ASN ASN C . n 
C 1 380 LYS 380 380 380 LYS LYS C . n 
C 1 381 LEU 381 381 381 LEU LEU C . n 
C 1 382 LEU 382 382 382 LEU LEU C . n 
C 1 383 GLN 383 383 383 GLN GLN C . n 
C 1 384 GLU 384 384 384 GLU GLU C . n 
C 1 385 LYS 385 385 385 LYS LYS C . n 
C 1 386 TRP 386 386 386 TRP TRP C . n 
C 1 387 ASP 387 387 387 ASP ASP C . n 
C 1 388 ARG 388 388 388 ARG ARG C . n 
C 1 389 LEU 389 389 389 LEU LEU C . n 
C 1 390 VAL 390 390 390 VAL VAL C . n 
C 1 391 SER 391 391 391 SER SER C . n 
C 1 392 ARG 392 392 392 ARG ARG C . n 
C 1 393 PHE 393 393 393 PHE PHE C . n 
C 1 394 PHE 394 394 394 PHE PHE C . n 
C 1 395 PHE 395 395 395 PHE PHE C . n 
C 1 396 ASN 396 396 396 ASN ASN C . n 
C 1 397 PHE 397 397 397 PHE PHE C . n 
C 1 398 ALA 398 398 398 ALA ALA C . n 
C 1 399 CYS 399 399 399 CYS CYS C . n 
C 1 400 TYR 400 400 400 TYR TYR C . n 
C 1 401 LEU 401 401 401 LEU LEU C . n 
C 1 402 VAL 402 402 402 VAL VAL C . n 
C 1 403 TYR 403 403 403 TYR TYR C . n 
C 1 404 MET 404 404 404 MET MET C . n 
C 1 405 PHE 405 405 405 PHE PHE C . n 
C 1 406 ILE 406 406 406 ILE ILE C . n 
C 1 407 PHE 407 407 407 PHE PHE C . n 
C 1 408 THR 408 408 408 THR THR C . n 
C 1 409 VAL 409 409 409 VAL VAL C . n 
C 1 410 VAL 410 410 410 VAL VAL C . n 
C 1 411 ALA 411 411 411 ALA ALA C . n 
C 1 412 TYR 412 412 412 TYR TYR C . n 
C 1 413 HIS 413 413 413 HIS HIS C . n 
C 1 414 GLN 414 414 414 GLN GLN C . n 
C 1 415 PRO 415 415 415 PRO PRO C . n 
C 1 416 SER 416 416 416 SER SER C . n 
C 1 417 LEU 417 417 417 LEU LEU C . n 
C 1 418 ASP 418 418 ?   ?   ?   C . n 
C 1 419 GLN 419 419 ?   ?   ?   C . n 
C 1 420 PRO 420 420 ?   ?   ?   C . n 
C 1 421 ALA 421 421 ?   ?   ?   C . n 
C 1 422 ILE 422 422 ?   ?   ?   C . n 
C 1 423 PRO 423 423 ?   ?   ?   C . n 
C 1 424 SER 424 424 ?   ?   ?   C . n 
C 1 425 SER 425 425 ?   ?   ?   C . n 
C 1 426 LYS 426 426 ?   ?   ?   C . n 
C 1 427 ALA 427 427 ?   ?   ?   C . n 
C 1 428 THR 428 428 ?   ?   ?   C . n 
C 1 429 PHE 429 429 429 PHE PHE C . n 
C 1 430 GLY 430 430 430 GLY GLY C . n 
C 1 431 GLU 431 431 431 GLU GLU C . n 
C 1 432 SER 432 432 432 SER SER C . n 
C 1 433 MET 433 433 433 MET MET C . n 
C 1 434 LEU 434 434 434 LEU LEU C . n 
C 1 435 LEU 435 435 435 LEU LEU C . n 
C 1 436 LEU 436 436 436 LEU LEU C . n 
C 1 437 GLY 437 437 437 GLY GLY C . n 
C 1 438 HIS 438 438 438 HIS HIS C . n 
C 1 439 ILE 439 439 439 ILE ILE C . n 
C 1 440 LEU 440 440 440 LEU LEU C . n 
C 1 441 ILE 441 441 441 ILE ILE C . n 
C 1 442 LEU 442 442 442 LEU LEU C . n 
C 1 443 LEU 443 443 443 LEU LEU C . n 
C 1 444 GLY 444 444 444 GLY GLY C . n 
C 1 445 GLY 445 445 445 GLY GLY C . n 
C 1 446 ILE 446 446 446 ILE ILE C . n 
C 1 447 TYR 447 447 447 TYR TYR C . n 
C 1 448 LEU 448 448 448 LEU LEU C . n 
C 1 449 LEU 449 449 449 LEU LEU C . n 
C 1 450 LEU 450 450 450 LEU LEU C . n 
C 1 451 GLY 451 451 451 GLY GLY C . n 
C 1 452 GLN 452 452 452 GLN GLN C . n 
C 1 453 LEU 453 453 453 LEU LEU C . n 
C 1 454 TRP 454 454 454 TRP TRP C . n 
C 1 455 TYR 455 455 455 TYR TYR C . n 
C 1 456 PHE 456 456 456 PHE PHE C . n 
C 1 457 TRP 457 457 457 TRP TRP C . n 
C 1 458 ARG 458 458 458 ARG ARG C . n 
C 1 459 ARG 459 459 459 ARG ARG C . n 
C 1 460 ARG 460 460 460 ARG ARG C . n 
C 1 461 LEU 461 461 461 LEU LEU C . n 
C 1 462 PHE 462 462 462 PHE PHE C . n 
C 1 463 ILE 463 463 463 ILE ILE C . n 
C 1 464 TRP 464 464 464 TRP TRP C . n 
C 1 465 ILE 465 465 465 ILE ILE C . n 
C 1 466 SER 466 466 466 SER SER C . n 
C 1 467 PHE 467 467 467 PHE PHE C . n 
C 1 468 MET 468 468 468 MET MET C . n 
C 1 469 ASP 469 469 469 ASP ASP C . n 
C 1 470 SER 470 470 470 SER SER C . n 
C 1 471 TYR 471 471 471 TYR TYR C . n 
C 1 472 PHE 472 472 472 PHE PHE C . n 
C 1 473 GLU 473 473 473 GLU GLU C . n 
C 1 474 ILE 474 474 474 ILE ILE C . n 
C 1 475 LEU 475 475 475 LEU LEU C . n 
C 1 476 PHE 476 476 476 PHE PHE C . n 
C 1 477 LEU 477 477 477 LEU LEU C . n 
C 1 478 LEU 478 478 478 LEU LEU C . n 
C 1 479 GLN 479 479 479 GLN GLN C . n 
C 1 480 ALA 480 480 480 ALA ALA C . n 
C 1 481 LEU 481 481 481 LEU LEU C . n 
C 1 482 LEU 482 482 482 LEU LEU C . n 
C 1 483 THR 483 483 483 THR THR C . n 
C 1 484 VAL 484 484 484 VAL VAL C . n 
C 1 485 LEU 485 485 485 LEU LEU C . n 
C 1 486 SER 486 486 486 SER SER C . n 
C 1 487 GLN 487 487 487 GLN GLN C . n 
C 1 488 VAL 488 488 488 VAL VAL C . n 
C 1 489 LEU 489 489 489 LEU LEU C . n 
C 1 490 ARG 490 490 490 ARG ARG C . n 
C 1 491 PHE 491 491 491 PHE PHE C . n 
C 1 492 MET 492 492 492 MET MET C . n 
C 1 493 GLU 493 493 493 GLU GLU C . n 
C 1 494 THR 494 494 494 THR THR C . n 
C 1 495 GLU 495 495 495 GLU GLU C . n 
C 1 496 TRP 496 496 496 TRP TRP C . n 
C 1 497 TYR 497 497 497 TYR TYR C . n 
C 1 498 LEU 498 498 498 LEU LEU C . n 
C 1 499 PRO 499 499 499 PRO PRO C . n 
C 1 500 LEU 500 500 500 LEU LEU C . n 
C 1 501 LEU 501 501 501 LEU LEU C . n 
C 1 502 VAL 502 502 502 VAL VAL C . n 
C 1 503 LEU 503 503 503 LEU LEU C . n 
C 1 504 SER 504 504 504 SER SER C . n 
C 1 505 LEU 505 505 505 LEU LEU C . n 
C 1 506 VAL 506 506 506 VAL VAL C . n 
C 1 507 LEU 507 507 507 LEU LEU C . n 
C 1 508 GLY 508 508 508 GLY GLY C . n 
C 1 509 TRP 509 509 509 TRP TRP C . n 
C 1 510 LEU 510 510 510 LEU LEU C . n 
C 1 511 ASN 511 511 511 ASN ASN C . n 
C 1 512 LEU 512 512 512 LEU LEU C . n 
C 1 513 LEU 513 513 513 LEU LEU C . n 
C 1 514 TYR 514 514 514 TYR TYR C . n 
C 1 515 TYR 515 515 515 TYR TYR C . n 
C 1 516 THR 516 516 516 THR THR C . n 
C 1 517 ARG 517 517 517 ARG ARG C . n 
C 1 518 GLY 518 518 518 GLY GLY C . n 
C 1 519 PHE 519 519 519 PHE PHE C . n 
C 1 520 GLN 520 520 520 GLN GLN C . n 
C 1 521 HIS 521 521 521 HIS HIS C . n 
C 1 522 THR 522 522 522 THR THR C . n 
C 1 523 GLY 523 523 523 GLY GLY C . n 
C 1 524 ILE 524 524 524 ILE ILE C . n 
C 1 525 TYR 525 525 525 TYR TYR C . n 
C 1 526 SER 526 526 526 SER SER C . n 
C 1 527 VAL 527 527 527 VAL VAL C . n 
C 1 528 MET 528 528 528 MET MET C . n 
C 1 529 ILE 529 529 529 ILE ILE C . n 
C 1 530 GLN 530 530 530 GLN GLN C . n 
C 1 531 LYS 531 531 531 LYS LYS C . n 
C 1 532 VAL 532 532 532 VAL VAL C . n 
C 1 533 ILE 533 533 533 ILE ILE C . n 
C 1 534 LEU 534 534 534 LEU LEU C . n 
C 1 535 ARG 535 535 535 ARG ARG C . n 
C 1 536 ASP 536 536 536 ASP ASP C . n 
C 1 537 LEU 537 537 537 LEU LEU C . n 
C 1 538 LEU 538 538 538 LEU LEU C . n 
C 1 539 ARG 539 539 539 ARG ARG C . n 
C 1 540 PHE 540 540 540 PHE PHE C . n 
C 1 541 LEU 541 541 541 LEU LEU C . n 
C 1 542 LEU 542 542 542 LEU LEU C . n 
C 1 543 VAL 543 543 543 VAL VAL C . n 
C 1 544 TYR 544 544 544 TYR TYR C . n 
C 1 545 LEU 545 545 545 LEU LEU C . n 
C 1 546 VAL 546 546 546 VAL VAL C . n 
C 1 547 PHE 547 547 547 PHE PHE C . n 
C 1 548 LEU 548 548 548 LEU LEU C . n 
C 1 549 PHE 549 549 549 PHE PHE C . n 
C 1 550 GLY 550 550 550 GLY GLY C . n 
C 1 551 PHE 551 551 551 PHE PHE C . n 
C 1 552 ALA 552 552 552 ALA ALA C . n 
C 1 553 VAL 553 553 553 VAL VAL C . n 
C 1 554 ALA 554 554 554 ALA ALA C . n 
C 1 555 LEU 555 555 555 LEU LEU C . n 
C 1 556 VAL 556 556 556 VAL VAL C . n 
C 1 557 SER 557 557 557 SER SER C . n 
C 1 558 LEU 558 558 558 LEU LEU C . n 
C 1 559 SER 559 559 559 SER SER C . n 
C 1 560 ARG 560 560 560 ARG ARG C . n 
C 1 561 GLU 561 561 561 GLU GLU C . n 
C 1 562 ALA 562 562 562 ALA ALA C . n 
C 1 563 ARG 563 563 563 ARG ARG C . n 
C 1 564 SER 564 564 ?   ?   ?   C . n 
C 1 565 PRO 565 565 ?   ?   ?   C . n 
C 1 566 LYS 566 566 ?   ?   ?   C . n 
C 1 567 ALA 567 567 ?   ?   ?   C . n 
C 1 568 PRO 568 568 ?   ?   ?   C . n 
C 1 569 GLU 569 569 ?   ?   ?   C . n 
C 1 570 ASP 570 570 ?   ?   ?   C . n 
C 1 571 ASN 571 571 ?   ?   ?   C . n 
C 1 572 ASN 572 572 ?   ?   ?   C . n 
C 1 573 SER 573 573 ?   ?   ?   C . n 
C 1 574 THR 574 574 ?   ?   ?   C . n 
C 1 575 VAL 575 575 ?   ?   ?   C . n 
C 1 576 THR 576 576 ?   ?   ?   C . n 
C 1 577 GLU 577 577 ?   ?   ?   C . n 
C 1 578 GLN 578 578 ?   ?   ?   C . n 
C 1 579 PRO 579 579 ?   ?   ?   C . n 
C 1 580 THR 580 580 ?   ?   ?   C . n 
C 1 581 VAL 581 581 ?   ?   ?   C . n 
C 1 582 GLY 582 582 ?   ?   ?   C . n 
C 1 583 GLN 583 583 ?   ?   ?   C . n 
C 1 584 GLU 584 584 ?   ?   ?   C . n 
C 1 585 GLU 585 585 ?   ?   ?   C . n 
C 1 586 GLU 586 586 ?   ?   ?   C . n 
C 1 587 PRO 587 587 ?   ?   ?   C . n 
C 1 588 ALA 588 588 ?   ?   ?   C . n 
C 1 589 PRO 589 589 589 PRO PRO C . n 
C 1 590 TYR 590 590 590 TYR TYR C . n 
C 1 591 ARG 591 591 591 ARG ARG C . n 
C 1 592 SER 592 592 592 SER SER C . n 
C 1 593 ILE 593 593 593 ILE ILE C . n 
C 1 594 LEU 594 594 594 LEU LEU C . n 
C 1 595 ASP 595 595 595 ASP ASP C . n 
C 1 596 ALA 596 596 596 ALA ALA C . n 
C 1 597 SER 597 597 597 SER SER C . n 
C 1 598 LEU 598 598 598 LEU LEU C . n 
C 1 599 GLU 599 599 599 GLU GLU C . n 
C 1 600 LEU 600 600 600 LEU LEU C . n 
C 1 601 PHE 601 601 601 PHE PHE C . n 
C 1 602 LYS 602 602 602 LYS LYS C . n 
C 1 603 PHE 603 603 603 PHE PHE C . n 
C 1 604 THR 604 604 604 THR THR C . n 
C 1 605 ILE 605 605 605 ILE ILE C . n 
C 1 606 GLY 606 606 606 GLY GLY C . n 
C 1 607 MET 607 607 607 MET MET C . n 
C 1 608 GLY 608 608 608 GLY GLY C . n 
C 1 609 GLU 609 609 609 GLU GLU C . n 
C 1 610 LEU 610 610 610 LEU LEU C . n 
C 1 611 ALA 611 611 611 ALA ALA C . n 
C 1 612 PHE 612 612 612 PHE PHE C . n 
C 1 613 GLN 613 613 613 GLN GLN C . n 
C 1 614 GLU 614 614 614 GLU GLU C . n 
C 1 615 GLN 615 615 615 GLN GLN C . n 
C 1 616 LEU 616 616 616 LEU LEU C . n 
C 1 617 ARG 617 617 617 ARG ARG C . n 
C 1 618 PHE 618 618 618 PHE PHE C . n 
C 1 619 ARG 619 619 619 ARG ARG C . n 
C 1 620 GLY 620 620 620 GLY GLY C . n 
C 1 621 VAL 621 621 621 VAL VAL C . n 
C 1 622 VAL 622 622 622 VAL VAL C . n 
C 1 623 LEU 623 623 623 LEU LEU C . n 
C 1 624 LEU 624 624 624 LEU LEU C . n 
C 1 625 LEU 625 625 625 LEU LEU C . n 
C 1 626 LEU 626 626 626 LEU LEU C . n 
C 1 627 LEU 627 627 627 LEU LEU C . n 
C 1 628 ALA 628 628 628 ALA ALA C . n 
C 1 629 TYR 629 629 629 TYR TYR C . n 
C 1 630 VAL 630 630 630 VAL VAL C . n 
C 1 631 LEU 631 631 631 LEU LEU C . n 
C 1 632 LEU 632 632 632 LEU LEU C . n 
C 1 633 THR 633 633 633 THR THR C . n 
C 1 634 TYR 634 634 634 TYR TYR C . n 
C 1 635 VAL 635 635 635 VAL VAL C . n 
C 1 636 LEU 636 636 636 LEU LEU C . n 
C 1 637 LEU 637 637 637 LEU LEU C . n 
C 1 638 LEU 638 638 638 LEU LEU C . n 
C 1 639 ASN 639 639 639 ASN ASN C . n 
C 1 640 MET 640 640 640 MET MET C . n 
C 1 641 LEU 641 641 641 LEU LEU C . n 
C 1 642 ILE 642 642 642 ILE ILE C . n 
C 1 643 ALA 643 643 643 ALA ALA C . n 
C 1 644 LEU 644 644 644 LEU LEU C . n 
C 1 645 MET 645 645 645 MET MET C . n 
C 1 646 SER 646 646 646 SER SER C . n 
C 1 647 GLU 647 647 647 GLU GLU C . n 
C 1 648 THR 648 648 648 THR THR C . n 
C 1 649 VAL 649 649 649 VAL VAL C . n 
C 1 650 ASN 650 650 650 ASN ASN C . n 
C 1 651 HIS 651 651 651 HIS HIS C . n 
C 1 652 VAL 652 652 652 VAL VAL C . n 
C 1 653 ALA 653 653 653 ALA ALA C . n 
C 1 654 ASP 654 654 654 ASP ASP C . n 
C 1 655 ASN 655 655 655 ASN ASN C . n 
C 1 656 SER 656 656 656 SER SER C . n 
C 1 657 TRP 657 657 657 TRP TRP C . n 
C 1 658 SER 658 658 658 SER SER C . n 
C 1 659 ILE 659 659 659 ILE ILE C . n 
C 1 660 TRP 660 660 660 TRP TRP C . n 
C 1 661 LYS 661 661 661 LYS LYS C . n 
C 1 662 LEU 662 662 662 LEU LEU C . n 
C 1 663 GLN 663 663 663 GLN GLN C . n 
C 1 664 LYS 664 664 664 LYS LYS C . n 
C 1 665 ALA 665 665 665 ALA ALA C . n 
C 1 666 ILE 666 666 666 ILE ILE C . n 
C 1 667 SER 667 667 667 SER SER C . n 
C 1 668 VAL 668 668 668 VAL VAL C . n 
C 1 669 LEU 669 669 669 LEU LEU C . n 
C 1 670 GLU 670 670 670 GLU GLU C . n 
C 1 671 MET 671 671 671 MET MET C . n 
C 1 672 GLU 672 672 672 GLU GLU C . n 
C 1 673 ASN 673 673 673 ASN ASN C . n 
C 1 674 GLY 674 674 674 GLY GLY C . n 
C 1 675 TYR 675 675 675 TYR TYR C . n 
C 1 676 TRP 676 676 676 TRP TRP C . n 
C 1 677 TRP 677 677 677 TRP TRP C . n 
C 1 678 CYS 678 678 678 CYS CYS C . n 
C 1 679 ARG 679 679 679 ARG ARG C . n 
C 1 680 ARG 680 680 680 ARG ARG C . n 
C 1 681 LYS 681 681 681 LYS LYS C . n 
C 1 682 LYS 682 682 682 LYS LYS C . n 
C 1 683 HIS 683 683 683 HIS HIS C . n 
C 1 684 ARG 684 684 684 ARG ARG C . n 
C 1 685 GLU 685 685 685 GLU GLU C . n 
C 1 686 GLY 686 686 686 GLY GLY C . n 
C 1 687 ARG 687 687 687 ARG ARG C . n 
C 1 688 LEU 688 688 688 LEU LEU C . n 
C 1 689 LEU 689 689 689 LEU LEU C . n 
C 1 690 LYS 690 690 690 LYS LYS C . n 
C 1 691 VAL 691 691 691 VAL VAL C . n 
C 1 692 GLY 692 692 692 GLY GLY C . n 
C 1 693 THR 693 693 693 THR THR C . n 
C 1 694 ARG 694 694 694 ARG ARG C . n 
C 1 695 GLY 695 695 695 GLY GLY C . n 
C 1 696 ASP 696 696 ?   ?   ?   C . n 
C 1 697 GLY 697 697 ?   ?   ?   C . n 
C 1 698 THR 698 698 ?   ?   ?   C . n 
C 1 699 PRO 699 699 699 PRO PRO C . n 
C 1 700 ASP 700 700 700 ASP ASP C . n 
C 1 701 GLU 701 701 701 GLU GLU C . n 
C 1 702 ARG 702 702 702 ARG ARG C . n 
C 1 703 TRP 703 703 703 TRP TRP C . n 
C 1 704 CYS 704 704 704 CYS CYS C . n 
C 1 705 PHE 705 705 705 PHE PHE C . n 
C 1 706 ARG 706 706 706 ARG ARG C . n 
C 1 707 VAL 707 707 707 VAL VAL C . n 
C 1 708 GLU 708 708 708 GLU GLU C . n 
C 1 709 GLU 709 709 709 GLU GLU C . n 
C 1 710 VAL 710 710 710 VAL VAL C . n 
C 1 711 ASN 711 711 711 ASN ASN C . n 
C 1 712 TRP 712 712 712 TRP TRP C . n 
C 1 713 ALA 713 713 713 ALA ALA C . n 
C 1 714 ALA 714 714 714 ALA ALA C . n 
C 1 715 TRP 715 715 715 TRP TRP C . n 
C 1 716 GLU 716 716 716 GLU GLU C . n 
C 1 717 LYS 717 717 717 LYS LYS C . n 
C 1 718 THR 718 718 718 THR THR C . n 
C 1 719 LEU 719 719 719 LEU LEU C . n 
C 1 720 PRO 720 720 ?   ?   ?   C . n 
C 1 721 THR 721 721 ?   ?   ?   C . n 
C 1 722 LEU 722 722 ?   ?   ?   C . n 
C 1 723 SER 723 723 ?   ?   ?   C . n 
C 1 724 GLU 724 724 ?   ?   ?   C . n 
C 1 725 ASP 725 725 ?   ?   ?   C . n 
C 1 726 PRO 726 726 ?   ?   ?   C . n 
C 1 727 SER 727 727 ?   ?   ?   C . n 
C 1 728 GLY 728 728 ?   ?   ?   C . n 
C 1 729 PRO 729 729 ?   ?   ?   C . n 
C 1 730 GLY 730 730 ?   ?   ?   C . n 
C 1 731 ILE 731 731 ?   ?   ?   C . n 
C 1 732 THR 732 732 ?   ?   ?   C . n 
C 1 733 GLY 733 733 ?   ?   ?   C . n 
C 1 734 ASN 734 734 ?   ?   ?   C . n 
C 1 735 LYS 735 735 ?   ?   ?   C . n 
C 1 736 LYS 736 736 ?   ?   ?   C . n 
C 1 737 ASN 737 737 ?   ?   ?   C . n 
C 1 738 PRO 738 738 ?   ?   ?   C . n 
C 1 739 THR 739 739 ?   ?   ?   C . n 
C 1 740 SER 740 740 ?   ?   ?   C . n 
C 1 741 LYS 741 741 ?   ?   ?   C . n 
C 1 742 PRO 742 742 ?   ?   ?   C . n 
C 1 743 GLY 743 743 ?   ?   ?   C . n 
C 1 744 LYS 744 744 ?   ?   ?   C . n 
C 1 745 ASN 745 745 ?   ?   ?   C . n 
C 1 746 SER 746 746 ?   ?   ?   C . n 
C 1 747 ALA 747 747 ?   ?   ?   C . n 
C 1 748 SER 748 748 ?   ?   ?   C . n 
C 1 749 GLU 749 749 ?   ?   ?   C . n 
C 1 750 GLU 750 750 ?   ?   ?   C . n 
C 1 751 ASP 751 751 ?   ?   ?   C . n 
C 1 752 HIS 752 752 ?   ?   ?   C . n 
C 1 753 LEU 753 753 ?   ?   ?   C . n 
C 1 754 PRO 754 754 ?   ?   ?   C . n 
C 1 755 LEU 755 755 ?   ?   ?   C . n 
C 1 756 GLN 756 756 ?   ?   ?   C . n 
C 1 757 VAL 757 757 ?   ?   ?   C . n 
C 1 758 LEU 758 758 ?   ?   ?   C . n 
C 1 759 GLN 759 759 ?   ?   ?   C . n 
C 1 760 SER 760 760 ?   ?   ?   C . n 
C 1 761 PRO 761 761 ?   ?   ?   C . n 
D 1 1   MET 1   1   ?   ?   ?   D . n 
D 1 2   THR 2   2   ?   ?   ?   D . n 
D 1 3   SER 3   3   ?   ?   ?   D . n 
D 1 4   ALA 4   4   ?   ?   ?   D . n 
D 1 5   SER 5   5   ?   ?   ?   D . n 
D 1 6   SER 6   6   ?   ?   ?   D . n 
D 1 7   PRO 7   7   ?   ?   ?   D . n 
D 1 8   PRO 8   8   ?   ?   ?   D . n 
D 1 9   ALA 9   9   ?   ?   ?   D . n 
D 1 10  PHE 10  10  ?   ?   ?   D . n 
D 1 11  ARG 11  11  ?   ?   ?   D . n 
D 1 12  LEU 12  12  ?   ?   ?   D . n 
D 1 13  GLU 13  13  ?   ?   ?   D . n 
D 1 14  THR 14  14  ?   ?   ?   D . n 
D 1 15  SER 15  15  ?   ?   ?   D . n 
D 1 16  ASP 16  16  ?   ?   ?   D . n 
D 1 17  GLY 17  17  ?   ?   ?   D . n 
D 1 18  ASP 18  18  ?   ?   ?   D . n 
D 1 19  GLU 19  19  ?   ?   ?   D . n 
D 1 20  GLU 20  20  ?   ?   ?   D . n 
D 1 21  GLY 21  21  ?   ?   ?   D . n 
D 1 22  ASN 22  22  ?   ?   ?   D . n 
D 1 23  ALA 23  23  ?   ?   ?   D . n 
D 1 24  GLU 24  24  ?   ?   ?   D . n 
D 1 25  VAL 25  25  ?   ?   ?   D . n 
D 1 26  ASN 26  26  ?   ?   ?   D . n 
D 1 27  LYS 27  27  ?   ?   ?   D . n 
D 1 28  GLY 28  28  ?   ?   ?   D . n 
D 1 29  LYS 29  29  ?   ?   ?   D . n 
D 1 30  GLN 30  30  ?   ?   ?   D . n 
D 1 31  GLU 31  31  ?   ?   ?   D . n 
D 1 32  PRO 32  32  ?   ?   ?   D . n 
D 1 33  PRO 33  33  ?   ?   ?   D . n 
D 1 34  PRO 34  34  ?   ?   ?   D . n 
D 1 35  MET 35  35  ?   ?   ?   D . n 
D 1 36  GLU 36  36  ?   ?   ?   D . n 
D 1 37  SER 37  37  ?   ?   ?   D . n 
D 1 38  PRO 38  38  ?   ?   ?   D . n 
D 1 39  PHE 39  39  ?   ?   ?   D . n 
D 1 40  GLN 40  40  ?   ?   ?   D . n 
D 1 41  ARG 41  41  ?   ?   ?   D . n 
D 1 42  GLU 42  42  ?   ?   ?   D . n 
D 1 43  ASP 43  43  ?   ?   ?   D . n 
D 1 44  ARG 44  44  ?   ?   ?   D . n 
D 1 45  ASN 45  45  ?   ?   ?   D . n 
D 1 46  SER 46  46  ?   ?   ?   D . n 
D 1 47  SER 47  47  ?   ?   ?   D . n 
D 1 48  PRO 48  48  ?   ?   ?   D . n 
D 1 49  GLN 49  49  ?   ?   ?   D . n 
D 1 50  ILE 50  50  ?   ?   ?   D . n 
D 1 51  LYS 51  51  ?   ?   ?   D . n 
D 1 52  VAL 52  52  ?   ?   ?   D . n 
D 1 53  ASN 53  53  ?   ?   ?   D . n 
D 1 54  LEU 54  54  ?   ?   ?   D . n 
D 1 55  ASN 55  55  ?   ?   ?   D . n 
D 1 56  PHE 56  56  ?   ?   ?   D . n 
D 1 57  ILE 57  57  ?   ?   ?   D . n 
D 1 58  LYS 58  58  ?   ?   ?   D . n 
D 1 59  ARG 59  59  ?   ?   ?   D . n 
D 1 60  PRO 60  60  ?   ?   ?   D . n 
D 1 61  PRO 61  61  ?   ?   ?   D . n 
D 1 62  LYS 62  62  ?   ?   ?   D . n 
D 1 63  ASN 63  63  ?   ?   ?   D . n 
D 1 64  THR 64  64  ?   ?   ?   D . n 
D 1 65  SER 65  65  ?   ?   ?   D . n 
D 1 66  ALA 66  66  ?   ?   ?   D . n 
D 1 67  PRO 67  67  ?   ?   ?   D . n 
D 1 68  SER 68  68  ?   ?   ?   D . n 
D 1 69  GLN 69  69  ?   ?   ?   D . n 
D 1 70  GLN 70  70  ?   ?   ?   D . n 
D 1 71  GLU 71  71  ?   ?   ?   D . n 
D 1 72  PRO 72  72  ?   ?   ?   D . n 
D 1 73  ASP 73  73  ?   ?   ?   D . n 
D 1 74  ARG 74  74  74  ARG ARG D . n 
D 1 75  PHE 75  75  75  PHE PHE D . n 
D 1 76  ASP 76  76  76  ASP ASP D . n 
D 1 77  ARG 77  77  77  ARG ARG D . n 
D 1 78  ASP 78  78  78  ASP ASP D . n 
D 1 79  ARG 79  79  79  ARG ARG D . n 
D 1 80  LEU 80  80  80  LEU LEU D . n 
D 1 81  PHE 81  81  81  PHE PHE D . n 
D 1 82  SER 82  82  82  SER SER D . n 
D 1 83  VAL 83  83  83  VAL VAL D . n 
D 1 84  VAL 84  84  84  VAL VAL D . n 
D 1 85  SER 85  85  85  SER SER D . n 
D 1 86  ARG 86  86  86  ARG ARG D . n 
D 1 87  GLY 87  87  87  GLY GLY D . n 
D 1 88  VAL 88  88  88  VAL VAL D . n 
D 1 89  PRO 89  89  89  PRO PRO D . n 
D 1 90  GLU 90  90  90  GLU GLU D . n 
D 1 91  GLU 91  91  91  GLU GLU D . n 
D 1 92  LEU 92  92  92  LEU LEU D . n 
D 1 93  THR 93  93  93  THR THR D . n 
D 1 94  GLY 94  94  94  GLY GLY D . n 
D 1 95  LEU 95  95  95  LEU LEU D . n 
D 1 96  LEU 96  96  96  LEU LEU D . n 
D 1 97  GLU 97  97  97  GLU GLU D . n 
D 1 98  TYR 98  98  98  TYR TYR D . n 
D 1 99  LEU 99  99  99  LEU LEU D . n 
D 1 100 ARG 100 100 100 ARG ARG D . n 
D 1 101 TRP 101 101 101 TRP TRP D . n 
D 1 102 ASN 102 102 102 ASN ASN D . n 
D 1 103 SER 103 103 103 SER SER D . n 
D 1 104 LYS 104 104 104 LYS LYS D . n 
D 1 105 TYR 105 105 105 TYR TYR D . n 
D 1 106 LEU 106 106 106 LEU LEU D . n 
D 1 107 THR 107 107 107 THR THR D . n 
D 1 108 ASP 108 108 108 ASP ASP D . n 
D 1 109 SER 109 109 109 SER SER D . n 
D 1 110 ALA 110 110 110 ALA ALA D . n 
D 1 111 TYR 111 111 111 TYR TYR D . n 
D 1 112 THR 112 112 112 THR THR D . n 
D 1 113 GLU 113 113 113 GLU GLU D . n 
D 1 114 GLY 114 114 114 GLY GLY D . n 
D 1 115 SER 115 115 115 SER SER D . n 
D 1 116 THR 116 116 116 THR THR D . n 
D 1 117 GLY 117 117 117 GLY GLY D . n 
D 1 118 LYS 118 118 118 LYS LYS D . n 
D 1 119 THR 119 119 119 THR THR D . n 
D 1 120 CYS 120 120 120 CYS CYS D . n 
D 1 121 LEU 121 121 121 LEU LEU D . n 
D 1 122 MET 122 122 122 MET MET D . n 
D 1 123 LYS 123 123 123 LYS LYS D . n 
D 1 124 ALA 124 124 124 ALA ALA D . n 
D 1 125 VAL 125 125 125 VAL VAL D . n 
D 1 126 LEU 126 126 126 LEU LEU D . n 
D 1 127 ASN 127 127 127 ASN ASN D . n 
D 1 128 LEU 128 128 128 LEU LEU D . n 
D 1 129 GLN 129 129 129 GLN GLN D . n 
D 1 130 ASP 130 130 130 ASP ASP D . n 
D 1 131 GLY 131 131 131 GLY GLY D . n 
D 1 132 VAL 132 132 132 VAL VAL D . n 
D 1 133 ASN 133 133 133 ASN ASN D . n 
D 1 134 ALA 134 134 134 ALA ALA D . n 
D 1 135 CYS 135 135 135 CYS CYS D . n 
D 1 136 ILE 136 136 136 ILE ILE D . n 
D 1 137 MET 137 137 137 MET MET D . n 
D 1 138 PRO 138 138 138 PRO PRO D . n 
D 1 139 LEU 139 139 139 LEU LEU D . n 
D 1 140 LEU 140 140 140 LEU LEU D . n 
D 1 141 GLN 141 141 141 GLN GLN D . n 
D 1 142 ILE 142 142 142 ILE ILE D . n 
D 1 143 ASP 143 143 143 ASP ASP D . n 
D 1 144 LYS 144 144 144 LYS LYS D . n 
D 1 145 ASP 145 145 145 ASP ASP D . n 
D 1 146 SER 146 146 146 SER SER D . n 
D 1 147 GLY 147 147 147 GLY GLY D . n 
D 1 148 ASN 148 148 148 ASN ASN D . n 
D 1 149 PRO 149 149 149 PRO PRO D . n 
D 1 150 LYS 150 150 150 LYS LYS D . n 
D 1 151 LEU 151 151 151 LEU LEU D . n 
D 1 152 LEU 152 152 152 LEU LEU D . n 
D 1 153 VAL 153 153 153 VAL VAL D . n 
D 1 154 ASN 154 154 154 ASN ASN D . n 
D 1 155 ALA 155 155 155 ALA ALA D . n 
D 1 156 GLN 156 156 156 GLN GLN D . n 
D 1 157 CYS 157 157 157 CYS CYS D . n 
D 1 158 THR 158 158 158 THR THR D . n 
D 1 159 ASP 159 159 159 ASP ASP D . n 
D 1 160 GLU 160 160 160 GLU GLU D . n 
D 1 161 PHE 161 161 161 PHE PHE D . n 
D 1 162 TYR 162 162 162 TYR TYR D . n 
D 1 163 GLN 163 163 163 GLN GLN D . n 
D 1 164 GLY 164 164 164 GLY GLY D . n 
D 1 165 HIS 165 165 165 HIS HIS D . n 
D 1 166 SER 166 166 166 SER SER D . n 
D 1 167 ALA 167 167 167 ALA ALA D . n 
D 1 168 LEU 168 168 168 LEU LEU D . n 
D 1 169 HIS 169 169 169 HIS HIS D . n 
D 1 170 ILE 170 170 170 ILE ILE D . n 
D 1 171 ALA 171 171 171 ALA ALA D . n 
D 1 172 ILE 172 172 172 ILE ILE D . n 
D 1 173 GLU 173 173 173 GLU GLU D . n 
D 1 174 LYS 174 174 174 LYS LYS D . n 
D 1 175 ARG 175 175 175 ARG ARG D . n 
D 1 176 SER 176 176 176 SER SER D . n 
D 1 177 LEU 177 177 177 LEU LEU D . n 
D 1 178 GLN 178 178 178 GLN GLN D . n 
D 1 179 CYS 179 179 179 CYS CYS D . n 
D 1 180 VAL 180 180 180 VAL VAL D . n 
D 1 181 LYS 181 181 181 LYS LYS D . n 
D 1 182 LEU 182 182 182 LEU LEU D . n 
D 1 183 LEU 183 183 183 LEU LEU D . n 
D 1 184 VAL 184 184 184 VAL VAL D . n 
D 1 185 GLU 185 185 185 GLU GLU D . n 
D 1 186 ASN 186 186 186 ASN ASN D . n 
D 1 187 GLY 187 187 187 GLY GLY D . n 
D 1 188 ALA 188 188 188 ALA ALA D . n 
D 1 189 ASP 189 189 189 ASP ASP D . n 
D 1 190 VAL 190 190 190 VAL VAL D . n 
D 1 191 HIS 191 191 191 HIS HIS D . n 
D 1 192 LEU 192 192 192 LEU LEU D . n 
D 1 193 ARG 193 193 193 ARG ARG D . n 
D 1 194 ALA 194 194 194 ALA ALA D . n 
D 1 195 CYS 195 195 195 CYS CYS D . n 
D 1 196 GLY 196 196 196 GLY GLY D . n 
D 1 197 ARG 197 197 197 ARG ARG D . n 
D 1 198 PHE 198 198 198 PHE PHE D . n 
D 1 199 PHE 199 199 199 PHE PHE D . n 
D 1 200 GLN 200 200 200 GLN GLN D . n 
D 1 201 LYS 201 201 201 LYS LYS D . n 
D 1 202 HIS 202 202 202 HIS HIS D . n 
D 1 203 GLN 203 203 203 GLN GLN D . n 
D 1 204 GLY 204 204 204 GLY GLY D . n 
D 1 205 THR 205 205 205 THR THR D . n 
D 1 206 CYS 206 206 206 CYS CYS D . n 
D 1 207 PHE 207 207 207 PHE PHE D . n 
D 1 208 TYR 208 208 208 TYR TYR D . n 
D 1 209 PHE 209 209 209 PHE PHE D . n 
D 1 210 GLY 210 210 210 GLY GLY D . n 
D 1 211 GLU 211 211 211 GLU GLU D . n 
D 1 212 LEU 212 212 212 LEU LEU D . n 
D 1 213 PRO 213 213 213 PRO PRO D . n 
D 1 214 LEU 214 214 214 LEU LEU D . n 
D 1 215 SER 215 215 215 SER SER D . n 
D 1 216 LEU 216 216 216 LEU LEU D . n 
D 1 217 ALA 217 217 217 ALA ALA D . n 
D 1 218 ALA 218 218 218 ALA ALA D . n 
D 1 219 CYS 219 219 219 CYS CYS D . n 
D 1 220 THR 220 220 220 THR THR D . n 
D 1 221 LYS 221 221 221 LYS LYS D . n 
D 1 222 GLN 222 222 222 GLN GLN D . n 
D 1 223 TRP 223 223 223 TRP TRP D . n 
D 1 224 ASP 224 224 224 ASP ASP D . n 
D 1 225 VAL 225 225 225 VAL VAL D . n 
D 1 226 VAL 226 226 226 VAL VAL D . n 
D 1 227 THR 227 227 227 THR THR D . n 
D 1 228 TYR 228 228 228 TYR TYR D . n 
D 1 229 LEU 229 229 229 LEU LEU D . n 
D 1 230 LEU 230 230 230 LEU LEU D . n 
D 1 231 GLU 231 231 231 GLU GLU D . n 
D 1 232 ASN 232 232 232 ASN ASN D . n 
D 1 233 PRO 233 233 233 PRO PRO D . n 
D 1 234 HIS 234 234 234 HIS HIS D . n 
D 1 235 GLN 235 235 235 GLN GLN D . n 
D 1 236 PRO 236 236 236 PRO PRO D . n 
D 1 237 ALA 237 237 237 ALA ALA D . n 
D 1 238 SER 238 238 238 SER SER D . n 
D 1 239 LEU 239 239 239 LEU LEU D . n 
D 1 240 GLU 240 240 240 GLU GLU D . n 
D 1 241 ALA 241 241 241 ALA ALA D . n 
D 1 242 THR 242 242 242 THR THR D . n 
D 1 243 ASP 243 243 243 ASP ASP D . n 
D 1 244 SER 244 244 244 SER SER D . n 
D 1 245 LEU 245 245 245 LEU LEU D . n 
D 1 246 GLY 246 246 246 GLY GLY D . n 
D 1 247 ASN 247 247 247 ASN ASN D . n 
D 1 248 THR 248 248 248 THR THR D . n 
D 1 249 VAL 249 249 249 VAL VAL D . n 
D 1 250 LEU 250 250 250 LEU LEU D . n 
D 1 251 HIS 251 251 251 HIS HIS D . n 
D 1 252 ALA 252 252 252 ALA ALA D . n 
D 1 253 LEU 253 253 253 LEU LEU D . n 
D 1 254 VAL 254 254 254 VAL VAL D . n 
D 1 255 MET 255 255 255 MET MET D . n 
D 1 256 ILE 256 256 256 ILE ILE D . n 
D 1 257 ALA 257 257 257 ALA ALA D . n 
D 1 258 ASP 258 258 258 ASP ASP D . n 
D 1 259 ASN 259 259 259 ASN ASN D . n 
D 1 260 SER 260 260 260 SER SER D . n 
D 1 261 PRO 261 261 261 PRO PRO D . n 
D 1 262 GLU 262 262 262 GLU GLU D . n 
D 1 263 ASN 263 263 263 ASN ASN D . n 
D 1 264 SER 264 264 264 SER SER D . n 
D 1 265 ALA 265 265 265 ALA ALA D . n 
D 1 266 LEU 266 266 266 LEU LEU D . n 
D 1 267 VAL 267 267 267 VAL VAL D . n 
D 1 268 ILE 268 268 268 ILE ILE D . n 
D 1 269 HIS 269 269 269 HIS HIS D . n 
D 1 270 MET 270 270 270 MET MET D . n 
D 1 271 TYR 271 271 271 TYR TYR D . n 
D 1 272 ASP 272 272 272 ASP ASP D . n 
D 1 273 GLY 273 273 273 GLY GLY D . n 
D 1 274 LEU 274 274 274 LEU LEU D . n 
D 1 275 LEU 275 275 275 LEU LEU D . n 
D 1 276 GLN 276 276 276 GLN GLN D . n 
D 1 277 MET 277 277 277 MET MET D . n 
D 1 278 GLY 278 278 278 GLY GLY D . n 
D 1 279 ALA 279 279 279 ALA ALA D . n 
D 1 280 ARG 280 280 280 ARG ARG D . n 
D 1 281 LEU 281 281 281 LEU LEU D . n 
D 1 282 CYS 282 282 282 CYS CYS D . n 
D 1 283 PRO 283 283 283 PRO PRO D . n 
D 1 284 THR 284 284 284 THR THR D . n 
D 1 285 VAL 285 285 285 VAL VAL D . n 
D 1 286 GLN 286 286 286 GLN GLN D . n 
D 1 287 LEU 287 287 287 LEU LEU D . n 
D 1 288 GLU 288 288 288 GLU GLU D . n 
D 1 289 GLU 289 289 289 GLU GLU D . n 
D 1 290 ILE 290 290 290 ILE ILE D . n 
D 1 291 SER 291 291 291 SER SER D . n 
D 1 292 ASN 292 292 292 ASN ASN D . n 
D 1 293 HIS 293 293 293 HIS HIS D . n 
D 1 294 GLN 294 294 294 GLN GLN D . n 
D 1 295 GLY 295 295 295 GLY GLY D . n 
D 1 296 LEU 296 296 296 LEU LEU D . n 
D 1 297 THR 297 297 297 THR THR D . n 
D 1 298 PRO 298 298 298 PRO PRO D . n 
D 1 299 LEU 299 299 299 LEU LEU D . n 
D 1 300 LYS 300 300 300 LYS LYS D . n 
D 1 301 LEU 301 301 301 LEU LEU D . n 
D 1 302 ALA 302 302 302 ALA ALA D . n 
D 1 303 ALA 303 303 303 ALA ALA D . n 
D 1 304 LYS 304 304 304 LYS LYS D . n 
D 1 305 GLU 305 305 305 GLU GLU D . n 
D 1 306 GLY 306 306 306 GLY GLY D . n 
D 1 307 LYS 307 307 307 LYS LYS D . n 
D 1 308 ILE 308 308 308 ILE ILE D . n 
D 1 309 GLU 309 309 309 GLU GLU D . n 
D 1 310 ILE 310 310 310 ILE ILE D . n 
D 1 311 PHE 311 311 311 PHE PHE D . n 
D 1 312 ARG 312 312 312 ARG ARG D . n 
D 1 313 HIS 313 313 313 HIS HIS D . n 
D 1 314 ILE 314 314 314 ILE ILE D . n 
D 1 315 LEU 315 315 315 LEU LEU D . n 
D 1 316 GLN 316 316 316 GLN GLN D . n 
D 1 317 ARG 317 317 317 ARG ARG D . n 
D 1 318 GLU 318 318 318 GLU GLU D . n 
D 1 319 PHE 319 319 319 PHE PHE D . n 
D 1 320 SER 320 320 320 SER SER D . n 
D 1 321 GLY 321 321 321 GLY GLY D . n 
D 1 322 PRO 322 322 322 PRO PRO D . n 
D 1 323 TYR 323 323 323 TYR TYR D . n 
D 1 324 GLN 324 324 324 GLN GLN D . n 
D 1 325 PRO 325 325 325 PRO PRO D . n 
D 1 326 LEU 326 326 326 LEU LEU D . n 
D 1 327 SER 327 327 327 SER SER D . n 
D 1 328 ARG 328 328 328 ARG ARG D . n 
D 1 329 LYS 329 329 329 LYS LYS D . n 
D 1 330 PHE 330 330 330 PHE PHE D . n 
D 1 331 THR 331 331 331 THR THR D . n 
D 1 332 GLU 332 332 332 GLU GLU D . n 
D 1 333 TRP 333 333 333 TRP TRP D . n 
D 1 334 CYS 334 334 334 CYS CYS D . n 
D 1 335 TYR 335 335 335 TYR TYR D . n 
D 1 336 GLY 336 336 336 GLY GLY D . n 
D 1 337 PRO 337 337 337 PRO PRO D . n 
D 1 338 VAL 338 338 338 VAL VAL D . n 
D 1 339 ARG 339 339 339 ARG ARG D . n 
D 1 340 VAL 340 340 340 VAL VAL D . n 
D 1 341 SER 341 341 341 SER SER D . n 
D 1 342 LEU 342 342 342 LEU LEU D . n 
D 1 343 TYR 343 343 343 TYR TYR D . n 
D 1 344 ASP 344 344 344 ASP ASP D . n 
D 1 345 LEU 345 345 345 LEU LEU D . n 
D 1 346 SER 346 346 346 SER SER D . n 
D 1 347 SER 347 347 347 SER SER D . n 
D 1 348 VAL 348 348 348 VAL VAL D . n 
D 1 349 ASP 349 349 349 ASP ASP D . n 
D 1 350 SER 350 350 350 SER SER D . n 
D 1 351 TRP 351 351 351 TRP TRP D . n 
D 1 352 GLU 352 352 352 GLU GLU D . n 
D 1 353 LYS 353 353 353 LYS LYS D . n 
D 1 354 ASN 354 354 354 ASN ASN D . n 
D 1 355 SER 355 355 355 SER SER D . n 
D 1 356 VAL 356 356 356 VAL VAL D . n 
D 1 357 LEU 357 357 357 LEU LEU D . n 
D 1 358 GLU 358 358 358 GLU GLU D . n 
D 1 359 ILE 359 359 359 ILE ILE D . n 
D 1 360 ILE 360 360 360 ILE ILE D . n 
D 1 361 ALA 361 361 361 ALA ALA D . n 
D 1 362 PHE 362 362 362 PHE PHE D . n 
D 1 363 HIS 363 363 363 HIS HIS D . n 
D 1 364 CYS 364 364 364 CYS CYS D . n 
D 1 365 LYS 365 365 365 LYS LYS D . n 
D 1 366 SER 366 366 366 SER SER D . n 
D 1 367 PRO 367 367 367 PRO PRO D . n 
D 1 368 ASN 368 368 368 ASN ASN D . n 
D 1 369 ARG 369 369 369 ARG ARG D . n 
D 1 370 HIS 370 370 370 HIS HIS D . n 
D 1 371 ARG 371 371 371 ARG ARG D . n 
D 1 372 MET 372 372 372 MET MET D . n 
D 1 373 VAL 373 373 373 VAL VAL D . n 
D 1 374 VAL 374 374 374 VAL VAL D . n 
D 1 375 LEU 375 375 375 LEU LEU D . n 
D 1 376 GLU 376 376 376 GLU GLU D . n 
D 1 377 PRO 377 377 377 PRO PRO D . n 
D 1 378 LEU 378 378 378 LEU LEU D . n 
D 1 379 ASN 379 379 379 ASN ASN D . n 
D 1 380 LYS 380 380 380 LYS LYS D . n 
D 1 381 LEU 381 381 381 LEU LEU D . n 
D 1 382 LEU 382 382 382 LEU LEU D . n 
D 1 383 GLN 383 383 383 GLN GLN D . n 
D 1 384 GLU 384 384 384 GLU GLU D . n 
D 1 385 LYS 385 385 385 LYS LYS D . n 
D 1 386 TRP 386 386 386 TRP TRP D . n 
D 1 387 ASP 387 387 387 ASP ASP D . n 
D 1 388 ARG 388 388 388 ARG ARG D . n 
D 1 389 LEU 389 389 389 LEU LEU D . n 
D 1 390 VAL 390 390 390 VAL VAL D . n 
D 1 391 SER 391 391 391 SER SER D . n 
D 1 392 ARG 392 392 392 ARG ARG D . n 
D 1 393 PHE 393 393 393 PHE PHE D . n 
D 1 394 PHE 394 394 394 PHE PHE D . n 
D 1 395 PHE 395 395 395 PHE PHE D . n 
D 1 396 ASN 396 396 396 ASN ASN D . n 
D 1 397 PHE 397 397 397 PHE PHE D . n 
D 1 398 ALA 398 398 398 ALA ALA D . n 
D 1 399 CYS 399 399 399 CYS CYS D . n 
D 1 400 TYR 400 400 400 TYR TYR D . n 
D 1 401 LEU 401 401 401 LEU LEU D . n 
D 1 402 VAL 402 402 402 VAL VAL D . n 
D 1 403 TYR 403 403 403 TYR TYR D . n 
D 1 404 MET 404 404 404 MET MET D . n 
D 1 405 PHE 405 405 405 PHE PHE D . n 
D 1 406 ILE 406 406 406 ILE ILE D . n 
D 1 407 PHE 407 407 407 PHE PHE D . n 
D 1 408 THR 408 408 408 THR THR D . n 
D 1 409 VAL 409 409 409 VAL VAL D . n 
D 1 410 VAL 410 410 410 VAL VAL D . n 
D 1 411 ALA 411 411 411 ALA ALA D . n 
D 1 412 TYR 412 412 412 TYR TYR D . n 
D 1 413 HIS 413 413 413 HIS HIS D . n 
D 1 414 GLN 414 414 414 GLN GLN D . n 
D 1 415 PRO 415 415 415 PRO PRO D . n 
D 1 416 SER 416 416 416 SER SER D . n 
D 1 417 LEU 417 417 417 LEU LEU D . n 
D 1 418 ASP 418 418 ?   ?   ?   D . n 
D 1 419 GLN 419 419 ?   ?   ?   D . n 
D 1 420 PRO 420 420 ?   ?   ?   D . n 
D 1 421 ALA 421 421 ?   ?   ?   D . n 
D 1 422 ILE 422 422 ?   ?   ?   D . n 
D 1 423 PRO 423 423 ?   ?   ?   D . n 
D 1 424 SER 424 424 ?   ?   ?   D . n 
D 1 425 SER 425 425 ?   ?   ?   D . n 
D 1 426 LYS 426 426 ?   ?   ?   D . n 
D 1 427 ALA 427 427 ?   ?   ?   D . n 
D 1 428 THR 428 428 ?   ?   ?   D . n 
D 1 429 PHE 429 429 429 PHE PHE D . n 
D 1 430 GLY 430 430 430 GLY GLY D . n 
D 1 431 GLU 431 431 431 GLU GLU D . n 
D 1 432 SER 432 432 432 SER SER D . n 
D 1 433 MET 433 433 433 MET MET D . n 
D 1 434 LEU 434 434 434 LEU LEU D . n 
D 1 435 LEU 435 435 435 LEU LEU D . n 
D 1 436 LEU 436 436 436 LEU LEU D . n 
D 1 437 GLY 437 437 437 GLY GLY D . n 
D 1 438 HIS 438 438 438 HIS HIS D . n 
D 1 439 ILE 439 439 439 ILE ILE D . n 
D 1 440 LEU 440 440 440 LEU LEU D . n 
D 1 441 ILE 441 441 441 ILE ILE D . n 
D 1 442 LEU 442 442 442 LEU LEU D . n 
D 1 443 LEU 443 443 443 LEU LEU D . n 
D 1 444 GLY 444 444 444 GLY GLY D . n 
D 1 445 GLY 445 445 445 GLY GLY D . n 
D 1 446 ILE 446 446 446 ILE ILE D . n 
D 1 447 TYR 447 447 447 TYR TYR D . n 
D 1 448 LEU 448 448 448 LEU LEU D . n 
D 1 449 LEU 449 449 449 LEU LEU D . n 
D 1 450 LEU 450 450 450 LEU LEU D . n 
D 1 451 GLY 451 451 451 GLY GLY D . n 
D 1 452 GLN 452 452 452 GLN GLN D . n 
D 1 453 LEU 453 453 453 LEU LEU D . n 
D 1 454 TRP 454 454 454 TRP TRP D . n 
D 1 455 TYR 455 455 455 TYR TYR D . n 
D 1 456 PHE 456 456 456 PHE PHE D . n 
D 1 457 TRP 457 457 457 TRP TRP D . n 
D 1 458 ARG 458 458 458 ARG ARG D . n 
D 1 459 ARG 459 459 459 ARG ARG D . n 
D 1 460 ARG 460 460 460 ARG ARG D . n 
D 1 461 LEU 461 461 461 LEU LEU D . n 
D 1 462 PHE 462 462 462 PHE PHE D . n 
D 1 463 ILE 463 463 463 ILE ILE D . n 
D 1 464 TRP 464 464 464 TRP TRP D . n 
D 1 465 ILE 465 465 465 ILE ILE D . n 
D 1 466 SER 466 466 466 SER SER D . n 
D 1 467 PHE 467 467 467 PHE PHE D . n 
D 1 468 MET 468 468 468 MET MET D . n 
D 1 469 ASP 469 469 469 ASP ASP D . n 
D 1 470 SER 470 470 470 SER SER D . n 
D 1 471 TYR 471 471 471 TYR TYR D . n 
D 1 472 PHE 472 472 472 PHE PHE D . n 
D 1 473 GLU 473 473 473 GLU GLU D . n 
D 1 474 ILE 474 474 474 ILE ILE D . n 
D 1 475 LEU 475 475 475 LEU LEU D . n 
D 1 476 PHE 476 476 476 PHE PHE D . n 
D 1 477 LEU 477 477 477 LEU LEU D . n 
D 1 478 LEU 478 478 478 LEU LEU D . n 
D 1 479 GLN 479 479 479 GLN GLN D . n 
D 1 480 ALA 480 480 480 ALA ALA D . n 
D 1 481 LEU 481 481 481 LEU LEU D . n 
D 1 482 LEU 482 482 482 LEU LEU D . n 
D 1 483 THR 483 483 483 THR THR D . n 
D 1 484 VAL 484 484 484 VAL VAL D . n 
D 1 485 LEU 485 485 485 LEU LEU D . n 
D 1 486 SER 486 486 486 SER SER D . n 
D 1 487 GLN 487 487 487 GLN GLN D . n 
D 1 488 VAL 488 488 488 VAL VAL D . n 
D 1 489 LEU 489 489 489 LEU LEU D . n 
D 1 490 ARG 490 490 490 ARG ARG D . n 
D 1 491 PHE 491 491 491 PHE PHE D . n 
D 1 492 MET 492 492 492 MET MET D . n 
D 1 493 GLU 493 493 493 GLU GLU D . n 
D 1 494 THR 494 494 494 THR THR D . n 
D 1 495 GLU 495 495 495 GLU GLU D . n 
D 1 496 TRP 496 496 496 TRP TRP D . n 
D 1 497 TYR 497 497 497 TYR TYR D . n 
D 1 498 LEU 498 498 498 LEU LEU D . n 
D 1 499 PRO 499 499 499 PRO PRO D . n 
D 1 500 LEU 500 500 500 LEU LEU D . n 
D 1 501 LEU 501 501 501 LEU LEU D . n 
D 1 502 VAL 502 502 502 VAL VAL D . n 
D 1 503 LEU 503 503 503 LEU LEU D . n 
D 1 504 SER 504 504 504 SER SER D . n 
D 1 505 LEU 505 505 505 LEU LEU D . n 
D 1 506 VAL 506 506 506 VAL VAL D . n 
D 1 507 LEU 507 507 507 LEU LEU D . n 
D 1 508 GLY 508 508 508 GLY GLY D . n 
D 1 509 TRP 509 509 509 TRP TRP D . n 
D 1 510 LEU 510 510 510 LEU LEU D . n 
D 1 511 ASN 511 511 511 ASN ASN D . n 
D 1 512 LEU 512 512 512 LEU LEU D . n 
D 1 513 LEU 513 513 513 LEU LEU D . n 
D 1 514 TYR 514 514 514 TYR TYR D . n 
D 1 515 TYR 515 515 515 TYR TYR D . n 
D 1 516 THR 516 516 516 THR THR D . n 
D 1 517 ARG 517 517 517 ARG ARG D . n 
D 1 518 GLY 518 518 518 GLY GLY D . n 
D 1 519 PHE 519 519 519 PHE PHE D . n 
D 1 520 GLN 520 520 520 GLN GLN D . n 
D 1 521 HIS 521 521 521 HIS HIS D . n 
D 1 522 THR 522 522 522 THR THR D . n 
D 1 523 GLY 523 523 523 GLY GLY D . n 
D 1 524 ILE 524 524 524 ILE ILE D . n 
D 1 525 TYR 525 525 525 TYR TYR D . n 
D 1 526 SER 526 526 526 SER SER D . n 
D 1 527 VAL 527 527 527 VAL VAL D . n 
D 1 528 MET 528 528 528 MET MET D . n 
D 1 529 ILE 529 529 529 ILE ILE D . n 
D 1 530 GLN 530 530 530 GLN GLN D . n 
D 1 531 LYS 531 531 531 LYS LYS D . n 
D 1 532 VAL 532 532 532 VAL VAL D . n 
D 1 533 ILE 533 533 533 ILE ILE D . n 
D 1 534 LEU 534 534 534 LEU LEU D . n 
D 1 535 ARG 535 535 535 ARG ARG D . n 
D 1 536 ASP 536 536 536 ASP ASP D . n 
D 1 537 LEU 537 537 537 LEU LEU D . n 
D 1 538 LEU 538 538 538 LEU LEU D . n 
D 1 539 ARG 539 539 539 ARG ARG D . n 
D 1 540 PHE 540 540 540 PHE PHE D . n 
D 1 541 LEU 541 541 541 LEU LEU D . n 
D 1 542 LEU 542 542 542 LEU LEU D . n 
D 1 543 VAL 543 543 543 VAL VAL D . n 
D 1 544 TYR 544 544 544 TYR TYR D . n 
D 1 545 LEU 545 545 545 LEU LEU D . n 
D 1 546 VAL 546 546 546 VAL VAL D . n 
D 1 547 PHE 547 547 547 PHE PHE D . n 
D 1 548 LEU 548 548 548 LEU LEU D . n 
D 1 549 PHE 549 549 549 PHE PHE D . n 
D 1 550 GLY 550 550 550 GLY GLY D . n 
D 1 551 PHE 551 551 551 PHE PHE D . n 
D 1 552 ALA 552 552 552 ALA ALA D . n 
D 1 553 VAL 553 553 553 VAL VAL D . n 
D 1 554 ALA 554 554 554 ALA ALA D . n 
D 1 555 LEU 555 555 555 LEU LEU D . n 
D 1 556 VAL 556 556 556 VAL VAL D . n 
D 1 557 SER 557 557 557 SER SER D . n 
D 1 558 LEU 558 558 558 LEU LEU D . n 
D 1 559 SER 559 559 559 SER SER D . n 
D 1 560 ARG 560 560 560 ARG ARG D . n 
D 1 561 GLU 561 561 561 GLU GLU D . n 
D 1 562 ALA 562 562 562 ALA ALA D . n 
D 1 563 ARG 563 563 563 ARG ARG D . n 
D 1 564 SER 564 564 ?   ?   ?   D . n 
D 1 565 PRO 565 565 ?   ?   ?   D . n 
D 1 566 LYS 566 566 ?   ?   ?   D . n 
D 1 567 ALA 567 567 ?   ?   ?   D . n 
D 1 568 PRO 568 568 ?   ?   ?   D . n 
D 1 569 GLU 569 569 ?   ?   ?   D . n 
D 1 570 ASP 570 570 ?   ?   ?   D . n 
D 1 571 ASN 571 571 ?   ?   ?   D . n 
D 1 572 ASN 572 572 ?   ?   ?   D . n 
D 1 573 SER 573 573 ?   ?   ?   D . n 
D 1 574 THR 574 574 ?   ?   ?   D . n 
D 1 575 VAL 575 575 ?   ?   ?   D . n 
D 1 576 THR 576 576 ?   ?   ?   D . n 
D 1 577 GLU 577 577 ?   ?   ?   D . n 
D 1 578 GLN 578 578 ?   ?   ?   D . n 
D 1 579 PRO 579 579 ?   ?   ?   D . n 
D 1 580 THR 580 580 ?   ?   ?   D . n 
D 1 581 VAL 581 581 ?   ?   ?   D . n 
D 1 582 GLY 582 582 ?   ?   ?   D . n 
D 1 583 GLN 583 583 ?   ?   ?   D . n 
D 1 584 GLU 584 584 ?   ?   ?   D . n 
D 1 585 GLU 585 585 ?   ?   ?   D . n 
D 1 586 GLU 586 586 ?   ?   ?   D . n 
D 1 587 PRO 587 587 ?   ?   ?   D . n 
D 1 588 ALA 588 588 ?   ?   ?   D . n 
D 1 589 PRO 589 589 589 PRO PRO D . n 
D 1 590 TYR 590 590 590 TYR TYR D . n 
D 1 591 ARG 591 591 591 ARG ARG D . n 
D 1 592 SER 592 592 592 SER SER D . n 
D 1 593 ILE 593 593 593 ILE ILE D . n 
D 1 594 LEU 594 594 594 LEU LEU D . n 
D 1 595 ASP 595 595 595 ASP ASP D . n 
D 1 596 ALA 596 596 596 ALA ALA D . n 
D 1 597 SER 597 597 597 SER SER D . n 
D 1 598 LEU 598 598 598 LEU LEU D . n 
D 1 599 GLU 599 599 599 GLU GLU D . n 
D 1 600 LEU 600 600 600 LEU LEU D . n 
D 1 601 PHE 601 601 601 PHE PHE D . n 
D 1 602 LYS 602 602 602 LYS LYS D . n 
D 1 603 PHE 603 603 603 PHE PHE D . n 
D 1 604 THR 604 604 604 THR THR D . n 
D 1 605 ILE 605 605 605 ILE ILE D . n 
D 1 606 GLY 606 606 606 GLY GLY D . n 
D 1 607 MET 607 607 607 MET MET D . n 
D 1 608 GLY 608 608 608 GLY GLY D . n 
D 1 609 GLU 609 609 609 GLU GLU D . n 
D 1 610 LEU 610 610 610 LEU LEU D . n 
D 1 611 ALA 611 611 611 ALA ALA D . n 
D 1 612 PHE 612 612 612 PHE PHE D . n 
D 1 613 GLN 613 613 613 GLN GLN D . n 
D 1 614 GLU 614 614 614 GLU GLU D . n 
D 1 615 GLN 615 615 615 GLN GLN D . n 
D 1 616 LEU 616 616 616 LEU LEU D . n 
D 1 617 ARG 617 617 617 ARG ARG D . n 
D 1 618 PHE 618 618 618 PHE PHE D . n 
D 1 619 ARG 619 619 619 ARG ARG D . n 
D 1 620 GLY 620 620 620 GLY GLY D . n 
D 1 621 VAL 621 621 621 VAL VAL D . n 
D 1 622 VAL 622 622 622 VAL VAL D . n 
D 1 623 LEU 623 623 623 LEU LEU D . n 
D 1 624 LEU 624 624 624 LEU LEU D . n 
D 1 625 LEU 625 625 625 LEU LEU D . n 
D 1 626 LEU 626 626 626 LEU LEU D . n 
D 1 627 LEU 627 627 627 LEU LEU D . n 
D 1 628 ALA 628 628 628 ALA ALA D . n 
D 1 629 TYR 629 629 629 TYR TYR D . n 
D 1 630 VAL 630 630 630 VAL VAL D . n 
D 1 631 LEU 631 631 631 LEU LEU D . n 
D 1 632 LEU 632 632 632 LEU LEU D . n 
D 1 633 THR 633 633 633 THR THR D . n 
D 1 634 TYR 634 634 634 TYR TYR D . n 
D 1 635 VAL 635 635 635 VAL VAL D . n 
D 1 636 LEU 636 636 636 LEU LEU D . n 
D 1 637 LEU 637 637 637 LEU LEU D . n 
D 1 638 LEU 638 638 638 LEU LEU D . n 
D 1 639 ASN 639 639 639 ASN ASN D . n 
D 1 640 MET 640 640 640 MET MET D . n 
D 1 641 LEU 641 641 641 LEU LEU D . n 
D 1 642 ILE 642 642 642 ILE ILE D . n 
D 1 643 ALA 643 643 643 ALA ALA D . n 
D 1 644 LEU 644 644 644 LEU LEU D . n 
D 1 645 MET 645 645 645 MET MET D . n 
D 1 646 SER 646 646 646 SER SER D . n 
D 1 647 GLU 647 647 647 GLU GLU D . n 
D 1 648 THR 648 648 648 THR THR D . n 
D 1 649 VAL 649 649 649 VAL VAL D . n 
D 1 650 ASN 650 650 650 ASN ASN D . n 
D 1 651 HIS 651 651 651 HIS HIS D . n 
D 1 652 VAL 652 652 652 VAL VAL D . n 
D 1 653 ALA 653 653 653 ALA ALA D . n 
D 1 654 ASP 654 654 654 ASP ASP D . n 
D 1 655 ASN 655 655 655 ASN ASN D . n 
D 1 656 SER 656 656 656 SER SER D . n 
D 1 657 TRP 657 657 657 TRP TRP D . n 
D 1 658 SER 658 658 658 SER SER D . n 
D 1 659 ILE 659 659 659 ILE ILE D . n 
D 1 660 TRP 660 660 660 TRP TRP D . n 
D 1 661 LYS 661 661 661 LYS LYS D . n 
D 1 662 LEU 662 662 662 LEU LEU D . n 
D 1 663 GLN 663 663 663 GLN GLN D . n 
D 1 664 LYS 664 664 664 LYS LYS D . n 
D 1 665 ALA 665 665 665 ALA ALA D . n 
D 1 666 ILE 666 666 666 ILE ILE D . n 
D 1 667 SER 667 667 667 SER SER D . n 
D 1 668 VAL 668 668 668 VAL VAL D . n 
D 1 669 LEU 669 669 669 LEU LEU D . n 
D 1 670 GLU 670 670 670 GLU GLU D . n 
D 1 671 MET 671 671 671 MET MET D . n 
D 1 672 GLU 672 672 672 GLU GLU D . n 
D 1 673 ASN 673 673 673 ASN ASN D . n 
D 1 674 GLY 674 674 674 GLY GLY D . n 
D 1 675 TYR 675 675 675 TYR TYR D . n 
D 1 676 TRP 676 676 676 TRP TRP D . n 
D 1 677 TRP 677 677 677 TRP TRP D . n 
D 1 678 CYS 678 678 678 CYS CYS D . n 
D 1 679 ARG 679 679 679 ARG ARG D . n 
D 1 680 ARG 680 680 680 ARG ARG D . n 
D 1 681 LYS 681 681 681 LYS LYS D . n 
D 1 682 LYS 682 682 682 LYS LYS D . n 
D 1 683 HIS 683 683 683 HIS HIS D . n 
D 1 684 ARG 684 684 684 ARG ARG D . n 
D 1 685 GLU 685 685 685 GLU GLU D . n 
D 1 686 GLY 686 686 686 GLY GLY D . n 
D 1 687 ARG 687 687 687 ARG ARG D . n 
D 1 688 LEU 688 688 688 LEU LEU D . n 
D 1 689 LEU 689 689 689 LEU LEU D . n 
D 1 690 LYS 690 690 690 LYS LYS D . n 
D 1 691 VAL 691 691 691 VAL VAL D . n 
D 1 692 GLY 692 692 692 GLY GLY D . n 
D 1 693 THR 693 693 693 THR THR D . n 
D 1 694 ARG 694 694 694 ARG ARG D . n 
D 1 695 GLY 695 695 695 GLY GLY D . n 
D 1 696 ASP 696 696 ?   ?   ?   D . n 
D 1 697 GLY 697 697 ?   ?   ?   D . n 
D 1 698 THR 698 698 ?   ?   ?   D . n 
D 1 699 PRO 699 699 699 PRO PRO D . n 
D 1 700 ASP 700 700 700 ASP ASP D . n 
D 1 701 GLU 701 701 701 GLU GLU D . n 
D 1 702 ARG 702 702 702 ARG ARG D . n 
D 1 703 TRP 703 703 703 TRP TRP D . n 
D 1 704 CYS 704 704 704 CYS CYS D . n 
D 1 705 PHE 705 705 705 PHE PHE D . n 
D 1 706 ARG 706 706 706 ARG ARG D . n 
D 1 707 VAL 707 707 707 VAL VAL D . n 
D 1 708 GLU 708 708 708 GLU GLU D . n 
D 1 709 GLU 709 709 709 GLU GLU D . n 
D 1 710 VAL 710 710 710 VAL VAL D . n 
D 1 711 ASN 711 711 711 ASN ASN D . n 
D 1 712 TRP 712 712 712 TRP TRP D . n 
D 1 713 ALA 713 713 713 ALA ALA D . n 
D 1 714 ALA 714 714 714 ALA ALA D . n 
D 1 715 TRP 715 715 715 TRP TRP D . n 
D 1 716 GLU 716 716 716 GLU GLU D . n 
D 1 717 LYS 717 717 717 LYS LYS D . n 
D 1 718 THR 718 718 718 THR THR D . n 
D 1 719 LEU 719 719 719 LEU LEU D . n 
D 1 720 PRO 720 720 ?   ?   ?   D . n 
D 1 721 THR 721 721 ?   ?   ?   D . n 
D 1 722 LEU 722 722 ?   ?   ?   D . n 
D 1 723 SER 723 723 ?   ?   ?   D . n 
D 1 724 GLU 724 724 ?   ?   ?   D . n 
D 1 725 ASP 725 725 ?   ?   ?   D . n 
D 1 726 PRO 726 726 ?   ?   ?   D . n 
D 1 727 SER 727 727 ?   ?   ?   D . n 
D 1 728 GLY 728 728 ?   ?   ?   D . n 
D 1 729 PRO 729 729 ?   ?   ?   D . n 
D 1 730 GLY 730 730 ?   ?   ?   D . n 
D 1 731 ILE 731 731 ?   ?   ?   D . n 
D 1 732 THR 732 732 ?   ?   ?   D . n 
D 1 733 GLY 733 733 ?   ?   ?   D . n 
D 1 734 ASN 734 734 ?   ?   ?   D . n 
D 1 735 LYS 735 735 ?   ?   ?   D . n 
D 1 736 LYS 736 736 ?   ?   ?   D . n 
D 1 737 ASN 737 737 ?   ?   ?   D . n 
D 1 738 PRO 738 738 ?   ?   ?   D . n 
D 1 739 THR 739 739 ?   ?   ?   D . n 
D 1 740 SER 740 740 ?   ?   ?   D . n 
D 1 741 LYS 741 741 ?   ?   ?   D . n 
D 1 742 PRO 742 742 ?   ?   ?   D . n 
D 1 743 GLY 743 743 ?   ?   ?   D . n 
D 1 744 LYS 744 744 ?   ?   ?   D . n 
D 1 745 ASN 745 745 ?   ?   ?   D . n 
D 1 746 SER 746 746 ?   ?   ?   D . n 
D 1 747 ALA 747 747 ?   ?   ?   D . n 
D 1 748 SER 748 748 ?   ?   ?   D . n 
D 1 749 GLU 749 749 ?   ?   ?   D . n 
D 1 750 GLU 750 750 ?   ?   ?   D . n 
D 1 751 ASP 751 751 ?   ?   ?   D . n 
D 1 752 HIS 752 752 ?   ?   ?   D . n 
D 1 753 LEU 753 753 ?   ?   ?   D . n 
D 1 754 PRO 754 754 ?   ?   ?   D . n 
D 1 755 LEU 755 755 ?   ?   ?   D . n 
D 1 756 GLN 756 756 ?   ?   ?   D . n 
D 1 757 VAL 757 757 ?   ?   ?   D . n 
D 1 758 LEU 758 758 ?   ?   ?   D . n 
D 1 759 GLN 759 759 ?   ?   ?   D . n 
D 1 760 SER 760 760 ?   ?   ?   D . n 
D 1 761 PRO 761 761 ?   ?   ?   D . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        RTO 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   RTO 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 2 PEX 1 801 802 PEX PEX A . 
F 3 RTO 1 802 805 RTO PBC A . 
G 3 RTO 1 803 805 RTO PBC A . 
H 2 PEX 1 801 802 PEX PEX B . 
I 3 RTO 1 802 805 RTO PBC B . 
J 2 PEX 1 801 802 PEX PEX C . 
K 3 RTO 1 802 805 RTO PBC C . 
L 2 PEX 1 801 802 PEX PEX D . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 A ARG 74  ? CB  ? A ARG 74  CB  
2   1 Y 1 A ARG 74  ? CG  ? A ARG 74  CG  
3   1 Y 1 A ARG 74  ? CD  ? A ARG 74  CD  
4   1 Y 1 A ARG 74  ? NE  ? A ARG 74  NE  
5   1 Y 1 A ARG 74  ? CZ  ? A ARG 74  CZ  
6   1 Y 1 A ARG 74  ? NH1 ? A ARG 74  NH1 
7   1 Y 1 A ARG 74  ? NH2 ? A ARG 74  NH2 
8   1 Y 1 A VAL 88  ? CB  ? A VAL 88  CB  
9   1 Y 1 A VAL 88  ? CG1 ? A VAL 88  CG1 
10  1 Y 1 A VAL 88  ? CG2 ? A VAL 88  CG2 
11  1 Y 1 A GLU 90  ? CB  ? A GLU 90  CB  
12  1 Y 1 A GLU 90  ? CG  ? A GLU 90  CG  
13  1 Y 1 A GLU 90  ? CD  ? A GLU 90  CD  
14  1 Y 1 A GLU 90  ? OE1 ? A GLU 90  OE1 
15  1 Y 1 A GLU 90  ? OE2 ? A GLU 90  OE2 
16  1 Y 1 A GLU 91  ? CB  ? A GLU 91  CB  
17  1 Y 1 A GLU 91  ? CG  ? A GLU 91  CG  
18  1 Y 1 A GLU 91  ? CD  ? A GLU 91  CD  
19  1 Y 1 A GLU 91  ? OE1 ? A GLU 91  OE1 
20  1 Y 1 A GLU 91  ? OE2 ? A GLU 91  OE2 
21  1 Y 1 A GLU 97  ? CB  ? A GLU 97  CB  
22  1 Y 1 A GLU 97  ? CG  ? A GLU 97  CG  
23  1 Y 1 A GLU 97  ? CD  ? A GLU 97  CD  
24  1 Y 1 A GLU 97  ? OE1 ? A GLU 97  OE1 
25  1 Y 1 A GLU 97  ? OE2 ? A GLU 97  OE2 
26  1 Y 1 A TRP 101 ? CG  ? A TRP 101 CG  
27  1 Y 1 A TRP 101 ? CD1 ? A TRP 101 CD1 
28  1 Y 1 A TRP 101 ? CD2 ? A TRP 101 CD2 
29  1 Y 1 A TRP 101 ? NE1 ? A TRP 101 NE1 
30  1 Y 1 A TRP 101 ? CE2 ? A TRP 101 CE2 
31  1 Y 1 A TRP 101 ? CE3 ? A TRP 101 CE3 
32  1 Y 1 A TRP 101 ? CZ2 ? A TRP 101 CZ2 
33  1 Y 1 A TRP 101 ? CZ3 ? A TRP 101 CZ3 
34  1 Y 1 A TRP 101 ? CH2 ? A TRP 101 CH2 
35  1 Y 1 A GLN 129 ? CB  ? A GLN 129 CB  
36  1 Y 1 A GLN 129 ? CG  ? A GLN 129 CG  
37  1 Y 1 A GLN 129 ? CD  ? A GLN 129 CD  
38  1 Y 1 A GLN 129 ? OE1 ? A GLN 129 OE1 
39  1 Y 1 A GLN 129 ? NE2 ? A GLN 129 NE2 
40  1 Y 1 A ASP 130 ? CG  ? A ASP 130 CG  
41  1 Y 1 A ASP 130 ? OD1 ? A ASP 130 OD1 
42  1 Y 1 A ASP 130 ? OD2 ? A ASP 130 OD2 
43  1 Y 1 A LYS 144 ? CB  ? A LYS 144 CB  
44  1 Y 1 A LYS 144 ? CG  ? A LYS 144 CG  
45  1 Y 1 A LYS 144 ? CD  ? A LYS 144 CD  
46  1 Y 1 A LYS 144 ? CE  ? A LYS 144 CE  
47  1 Y 1 A LYS 144 ? NZ  ? A LYS 144 NZ  
48  1 Y 1 A GLU 262 ? CB  ? A GLU 262 CB  
49  1 Y 1 A GLU 262 ? CG  ? A GLU 262 CG  
50  1 Y 1 A GLU 262 ? CD  ? A GLU 262 CD  
51  1 Y 1 A GLU 262 ? OE1 ? A GLU 262 OE1 
52  1 Y 1 A GLU 262 ? OE2 ? A GLU 262 OE2 
53  1 Y 1 A GLU 431 ? CG  ? A GLU 431 CG  
54  1 Y 1 A GLU 431 ? CD  ? A GLU 431 CD  
55  1 Y 1 A GLU 431 ? OE1 ? A GLU 431 OE1 
56  1 Y 1 A GLU 431 ? OE2 ? A GLU 431 OE2 
57  1 Y 1 A TRP 464 ? CG  ? A TRP 464 CG  
58  1 Y 1 A TRP 464 ? CD1 ? A TRP 464 CD1 
59  1 Y 1 A TRP 464 ? CD2 ? A TRP 464 CD2 
60  1 Y 1 A TRP 464 ? NE1 ? A TRP 464 NE1 
61  1 Y 1 A TRP 464 ? CE2 ? A TRP 464 CE2 
62  1 Y 1 A TRP 464 ? CE3 ? A TRP 464 CE3 
63  1 Y 1 A TRP 464 ? CZ2 ? A TRP 464 CZ2 
64  1 Y 1 A TRP 464 ? CZ3 ? A TRP 464 CZ3 
65  1 Y 1 A TRP 464 ? CH2 ? A TRP 464 CH2 
66  1 Y 1 A PHE 491 ? CB  ? A PHE 491 CB  
67  1 Y 1 A PHE 491 ? CG  ? A PHE 491 CG  
68  1 Y 1 A PHE 491 ? CD1 ? A PHE 491 CD1 
69  1 Y 1 A PHE 491 ? CD2 ? A PHE 491 CD2 
70  1 Y 1 A PHE 491 ? CE1 ? A PHE 491 CE1 
71  1 Y 1 A PHE 491 ? CE2 ? A PHE 491 CE2 
72  1 Y 1 A PHE 491 ? CZ  ? A PHE 491 CZ  
73  1 Y 1 A GLU 493 ? CG  ? A GLU 493 CG  
74  1 Y 1 A GLU 493 ? CD  ? A GLU 493 CD  
75  1 Y 1 A GLU 493 ? OE1 ? A GLU 493 OE1 
76  1 Y 1 A GLU 493 ? OE2 ? A GLU 493 OE2 
77  1 Y 1 A ARG 563 ? CG  ? A ARG 563 CG  
78  1 Y 1 A ARG 563 ? CD  ? A ARG 563 CD  
79  1 Y 1 A ARG 563 ? NE  ? A ARG 563 NE  
80  1 Y 1 A ARG 563 ? CZ  ? A ARG 563 CZ  
81  1 Y 1 A ARG 563 ? NH1 ? A ARG 563 NH1 
82  1 Y 1 A ARG 563 ? NH2 ? A ARG 563 NH2 
83  1 Y 1 A ARG 591 ? CG  ? A ARG 591 CG  
84  1 Y 1 A ARG 591 ? CD  ? A ARG 591 CD  
85  1 Y 1 A ARG 591 ? NE  ? A ARG 591 NE  
86  1 Y 1 A ARG 591 ? CZ  ? A ARG 591 CZ  
87  1 Y 1 A ARG 591 ? NH1 ? A ARG 591 NH1 
88  1 Y 1 A ARG 591 ? NH2 ? A ARG 591 NH2 
89  1 Y 1 A LYS 681 ? CB  ? A LYS 681 CB  
90  1 Y 1 A LYS 681 ? CG  ? A LYS 681 CG  
91  1 Y 1 A LYS 681 ? CD  ? A LYS 681 CD  
92  1 Y 1 A LYS 681 ? CE  ? A LYS 681 CE  
93  1 Y 1 A LYS 681 ? NZ  ? A LYS 681 NZ  
94  1 Y 1 A ARG 694 ? C   ? A ARG 694 C   
95  1 Y 1 A ARG 694 ? O   ? A ARG 694 O   
96  1 Y 1 B TRP 101 ? CG  ? B TRP 101 CG  
97  1 Y 1 B TRP 101 ? CD1 ? B TRP 101 CD1 
98  1 Y 1 B TRP 101 ? CD2 ? B TRP 101 CD2 
99  1 Y 1 B TRP 101 ? NE1 ? B TRP 101 NE1 
100 1 Y 1 B TRP 101 ? CE2 ? B TRP 101 CE2 
101 1 Y 1 B TRP 101 ? CE3 ? B TRP 101 CE3 
102 1 Y 1 B TRP 101 ? CZ2 ? B TRP 101 CZ2 
103 1 Y 1 B TRP 101 ? CZ3 ? B TRP 101 CZ3 
104 1 Y 1 B TRP 101 ? CH2 ? B TRP 101 CH2 
105 1 Y 1 B ASP 130 ? CG  ? B ASP 130 CG  
106 1 Y 1 B ASP 130 ? OD1 ? B ASP 130 OD1 
107 1 Y 1 B ASP 130 ? OD2 ? B ASP 130 OD2 
108 1 Y 1 B GLU 431 ? CG  ? B GLU 431 CG  
109 1 Y 1 B GLU 431 ? CD  ? B GLU 431 CD  
110 1 Y 1 B GLU 431 ? OE1 ? B GLU 431 OE1 
111 1 Y 1 B GLU 431 ? OE2 ? B GLU 431 OE2 
112 1 Y 1 B TRP 464 ? CG  ? B TRP 464 CG  
113 1 Y 1 B TRP 464 ? CD1 ? B TRP 464 CD1 
114 1 Y 1 B TRP 464 ? CD2 ? B TRP 464 CD2 
115 1 Y 1 B TRP 464 ? NE1 ? B TRP 464 NE1 
116 1 Y 1 B TRP 464 ? CE2 ? B TRP 464 CE2 
117 1 Y 1 B TRP 464 ? CE3 ? B TRP 464 CE3 
118 1 Y 1 B TRP 464 ? CZ2 ? B TRP 464 CZ2 
119 1 Y 1 B TRP 464 ? CZ3 ? B TRP 464 CZ3 
120 1 Y 1 B TRP 464 ? CH2 ? B TRP 464 CH2 
121 1 Y 1 B GLU 493 ? CG  ? B GLU 493 CG  
122 1 Y 1 B GLU 493 ? CD  ? B GLU 493 CD  
123 1 Y 1 B GLU 493 ? OE1 ? B GLU 493 OE1 
124 1 Y 1 B GLU 493 ? OE2 ? B GLU 493 OE2 
125 1 Y 1 B ARG 563 ? CG  ? B ARG 563 CG  
126 1 Y 1 B ARG 563 ? CD  ? B ARG 563 CD  
127 1 Y 1 B ARG 563 ? NE  ? B ARG 563 NE  
128 1 Y 1 B ARG 563 ? CZ  ? B ARG 563 CZ  
129 1 Y 1 B ARG 563 ? NH1 ? B ARG 563 NH1 
130 1 Y 1 B ARG 563 ? NH2 ? B ARG 563 NH2 
131 1 Y 1 B ARG 591 ? CG  ? B ARG 591 CG  
132 1 Y 1 B ARG 591 ? CD  ? B ARG 591 CD  
133 1 Y 1 B ARG 591 ? NE  ? B ARG 591 NE  
134 1 Y 1 B ARG 591 ? CZ  ? B ARG 591 CZ  
135 1 Y 1 B ARG 591 ? NH1 ? B ARG 591 NH1 
136 1 Y 1 B ARG 591 ? NH2 ? B ARG 591 NH2 
137 1 Y 1 C TRP 101 ? CG  ? C TRP 101 CG  
138 1 Y 1 C TRP 101 ? CD1 ? C TRP 101 CD1 
139 1 Y 1 C TRP 101 ? CD2 ? C TRP 101 CD2 
140 1 Y 1 C TRP 101 ? NE1 ? C TRP 101 NE1 
141 1 Y 1 C TRP 101 ? CE2 ? C TRP 101 CE2 
142 1 Y 1 C TRP 101 ? CE3 ? C TRP 101 CE3 
143 1 Y 1 C TRP 101 ? CZ2 ? C TRP 101 CZ2 
144 1 Y 1 C TRP 101 ? CZ3 ? C TRP 101 CZ3 
145 1 Y 1 C TRP 101 ? CH2 ? C TRP 101 CH2 
146 1 Y 1 C ASP 130 ? CG  ? C ASP 130 CG  
147 1 Y 1 C ASP 130 ? OD1 ? C ASP 130 OD1 
148 1 Y 1 C ASP 130 ? OD2 ? C ASP 130 OD2 
149 1 Y 1 C GLU 431 ? CG  ? C GLU 431 CG  
150 1 Y 1 C GLU 431 ? CD  ? C GLU 431 CD  
151 1 Y 1 C GLU 431 ? OE1 ? C GLU 431 OE1 
152 1 Y 1 C GLU 431 ? OE2 ? C GLU 431 OE2 
153 1 Y 1 C TRP 464 ? CG  ? C TRP 464 CG  
154 1 Y 1 C TRP 464 ? CD1 ? C TRP 464 CD1 
155 1 Y 1 C TRP 464 ? CD2 ? C TRP 464 CD2 
156 1 Y 1 C TRP 464 ? NE1 ? C TRP 464 NE1 
157 1 Y 1 C TRP 464 ? CE2 ? C TRP 464 CE2 
158 1 Y 1 C TRP 464 ? CE3 ? C TRP 464 CE3 
159 1 Y 1 C TRP 464 ? CZ2 ? C TRP 464 CZ2 
160 1 Y 1 C TRP 464 ? CZ3 ? C TRP 464 CZ3 
161 1 Y 1 C TRP 464 ? CH2 ? C TRP 464 CH2 
162 1 Y 1 C GLU 493 ? CG  ? C GLU 493 CG  
163 1 Y 1 C GLU 493 ? CD  ? C GLU 493 CD  
164 1 Y 1 C GLU 493 ? OE1 ? C GLU 493 OE1 
165 1 Y 1 C GLU 493 ? OE2 ? C GLU 493 OE2 
166 1 Y 1 C ARG 563 ? CG  ? C ARG 563 CG  
167 1 Y 1 C ARG 563 ? CD  ? C ARG 563 CD  
168 1 Y 1 C ARG 563 ? NE  ? C ARG 563 NE  
169 1 Y 1 C ARG 563 ? CZ  ? C ARG 563 CZ  
170 1 Y 1 C ARG 563 ? NH1 ? C ARG 563 NH1 
171 1 Y 1 C ARG 563 ? NH2 ? C ARG 563 NH2 
172 1 Y 1 C ARG 591 ? CG  ? C ARG 591 CG  
173 1 Y 1 C ARG 591 ? CD  ? C ARG 591 CD  
174 1 Y 1 C ARG 591 ? NE  ? C ARG 591 NE  
175 1 Y 1 C ARG 591 ? CZ  ? C ARG 591 CZ  
176 1 Y 1 C ARG 591 ? NH1 ? C ARG 591 NH1 
177 1 Y 1 C ARG 591 ? NH2 ? C ARG 591 NH2 
178 1 Y 1 D TRP 101 ? CG  ? D TRP 101 CG  
179 1 Y 1 D TRP 101 ? CD1 ? D TRP 101 CD1 
180 1 Y 1 D TRP 101 ? CD2 ? D TRP 101 CD2 
181 1 Y 1 D TRP 101 ? NE1 ? D TRP 101 NE1 
182 1 Y 1 D TRP 101 ? CE2 ? D TRP 101 CE2 
183 1 Y 1 D TRP 101 ? CE3 ? D TRP 101 CE3 
184 1 Y 1 D TRP 101 ? CZ2 ? D TRP 101 CZ2 
185 1 Y 1 D TRP 101 ? CZ3 ? D TRP 101 CZ3 
186 1 Y 1 D TRP 101 ? CH2 ? D TRP 101 CH2 
187 1 Y 1 D ASP 130 ? CG  ? D ASP 130 CG  
188 1 Y 1 D ASP 130 ? OD1 ? D ASP 130 OD1 
189 1 Y 1 D ASP 130 ? OD2 ? D ASP 130 OD2 
190 1 Y 1 D GLU 431 ? CG  ? D GLU 431 CG  
191 1 Y 1 D GLU 431 ? CD  ? D GLU 431 CD  
192 1 Y 1 D GLU 431 ? OE1 ? D GLU 431 OE1 
193 1 Y 1 D GLU 431 ? OE2 ? D GLU 431 OE2 
194 1 Y 1 D TRP 464 ? CG  ? D TRP 464 CG  
195 1 Y 1 D TRP 464 ? CD1 ? D TRP 464 CD1 
196 1 Y 1 D TRP 464 ? CD2 ? D TRP 464 CD2 
197 1 Y 1 D TRP 464 ? NE1 ? D TRP 464 NE1 
198 1 Y 1 D TRP 464 ? CE2 ? D TRP 464 CE2 
199 1 Y 1 D TRP 464 ? CE3 ? D TRP 464 CE3 
200 1 Y 1 D TRP 464 ? CZ2 ? D TRP 464 CZ2 
201 1 Y 1 D TRP 464 ? CZ3 ? D TRP 464 CZ3 
202 1 Y 1 D TRP 464 ? CH2 ? D TRP 464 CH2 
203 1 Y 1 D GLU 493 ? CG  ? D GLU 493 CG  
204 1 Y 1 D GLU 493 ? CD  ? D GLU 493 CD  
205 1 Y 1 D GLU 493 ? OE1 ? D GLU 493 OE1 
206 1 Y 1 D GLU 493 ? OE2 ? D GLU 493 OE2 
207 1 Y 1 D ARG 563 ? CG  ? D ARG 563 CG  
208 1 Y 1 D ARG 563 ? CD  ? D ARG 563 CD  
209 1 Y 1 D ARG 563 ? NE  ? D ARG 563 NE  
210 1 Y 1 D ARG 563 ? CZ  ? D ARG 563 CZ  
211 1 Y 1 D ARG 563 ? NH1 ? D ARG 563 NH1 
212 1 Y 1 D ARG 563 ? NH2 ? D ARG 563 NH2 
213 1 Y 1 D ARG 591 ? CG  ? D ARG 591 CG  
214 1 Y 1 D ARG 591 ? CD  ? D ARG 591 CD  
215 1 Y 1 D ARG 591 ? NE  ? D ARG 591 NE  
216 1 Y 1 D ARG 591 ? CZ  ? D ARG 591 CZ  
217 1 Y 1 D ARG 591 ? NH1 ? D ARG 591 NH1 
218 1 Y 1 D ARG 591 ? NH2 ? D ARG 591 NH2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9B3U 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9B3U 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9B3U 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9B3U 
_struct.title                        'Rat TRPV2 WT bound to probenecid' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9B3U 
_struct_keywords.text            'TRPV2, TRP channel, ion channel, probenecid, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 2 ? 
F N N 3 ? 
G N N 3 ? 
H N N 2 ? 
I N N 3 ? 
J N N 2 ? 
K N N 3 ? 
L N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    TRPV2_RAT 
_struct_ref.pdbx_db_accession          Q9WUD2 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MTSASSPPAFRLETSDGDEEGNAEVNKGKQEPPPMESPFQREDRNSSPQIKVNLNFIKRPPKNTSAPSQQEPDRFDRDRL
FSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDE
FYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLE
ATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFS
GPYQPLSRKFTEWCYGPVRVSLYDLSSVDSWEKNSVLEIIAFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNFACY
LVYMFIFTVVAYHQPSLDQPAIPSSKATFGESMLLLGHILILLGGIYLLLGQLWYFWRRRLFIWISFMDSYFEILFLLQA
LLTVLSQVLRFMETEWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSR
EARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNM
LIALMSETVNHVADNSWSIWKLQKAISVLEMENGYWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEEVNWAAWEKTLP
TLSEDPSGPGITGNKKNPTSKPGKNSASEEDHLPLQVLQSP
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9B3U A 1 ? 761 ? Q9WUD2 1 ? 761 ? 1 761 
2 1 9B3U B 1 ? 761 ? Q9WUD2 1 ? 761 ? 1 761 
3 1 9B3U C 1 ? 761 ? Q9WUD2 1 ? 761 ? 1 761 
4 1 9B3U D 1 ? 761 ? Q9WUD2 1 ? 761 ? 1 761 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1   AA1 ASP A 76  ? VAL A 84  ? ASP A 76  VAL A 84  1 ? 9  
HELX_P HELX_P2   AA2 PRO A 89  ? THR A 93  ? PRO A 89  THR A 93  5 ? 5  
HELX_P HELX_P3   AA3 GLY A 94  ? ASN A 102 ? GLY A 94  ASN A 102 1 ? 9  
HELX_P HELX_P4   AA4 ASP A 108 ? THR A 112 ? ASP A 108 THR A 112 5 ? 5  
HELX_P HELX_P5   AA5 THR A 119 ? LEU A 126 ? THR A 119 LEU A 126 1 ? 8  
HELX_P HELX_P6   AA6 CYS A 135 ? SER A 146 ? CYS A 135 SER A 146 1 ? 12 
HELX_P HELX_P7   AA7 LEU A 151 ? ALA A 155 ? LEU A 151 ALA A 155 5 ? 5  
HELX_P HELX_P8   AA8 SER A 166 ? LYS A 174 ? SER A 166 LYS A 174 1 ? 9  
HELX_P HELX_P9   AA9 SER A 176 ? ASN A 186 ? SER A 176 ASN A 186 1 ? 11 
HELX_P HELX_P10  AB1 GLY A 196 ? GLN A 200 ? GLY A 196 GLN A 200 5 ? 5  
HELX_P HELX_P11  AB2 LEU A 212 ? THR A 220 ? LEU A 212 THR A 220 1 ? 9  
HELX_P HELX_P12  AB3 GLN A 222 ? ASN A 232 ? GLN A 222 ASN A 232 1 ? 11 
HELX_P HELX_P13  AB4 THR A 248 ? ALA A 257 ? THR A 248 ALA A 257 1 ? 10 
HELX_P HELX_P14  AB5 SER A 260 ? CYS A 282 ? SER A 260 CYS A 282 1 ? 23 
HELX_P HELX_P15  AB6 GLN A 286 ? ILE A 290 ? GLN A 286 ILE A 290 5 ? 5  
HELX_P HELX_P16  AB7 THR A 297 ? GLU A 305 ? THR A 297 GLU A 305 1 ? 9  
HELX_P HELX_P17  AB8 LYS A 307 ? GLN A 316 ? LYS A 307 GLN A 316 1 ? 10 
HELX_P HELX_P18  AB9 SER A 320 ? SER A 327 ? SER A 320 SER A 327 5 ? 8  
HELX_P HELX_P19  AC1 SER A 355 ? HIS A 363 ? SER A 355 HIS A 363 1 ? 9  
HELX_P HELX_P20  AC2 ASN A 368 ? VAL A 373 ? ASN A 368 VAL A 373 1 ? 6  
HELX_P HELX_P21  AC3 PRO A 377 ? ARG A 388 ? PRO A 377 ARG A 388 1 ? 12 
HELX_P HELX_P22  AC4 LEU A 389 ? HIS A 413 ? LEU A 389 HIS A 413 1 ? 25 
HELX_P HELX_P23  AC5 GLY A 430 ? ARG A 459 ? GLY A 430 ARG A 459 1 ? 30 
HELX_P HELX_P24  AC6 PHE A 462 ? PHE A 467 ? PHE A 462 PHE A 467 1 ? 6  
HELX_P HELX_P25  AC7 TYR A 471 ? MET A 492 ? TYR A 471 MET A 492 1 ? 22 
HELX_P HELX_P26  AC8 TRP A 496 ? LEU A 512 ? TRP A 496 LEU A 512 1 ? 17 
HELX_P HELX_P27  AC9 LEU A 513 ? GLY A 518 ? LEU A 513 GLY A 518 5 ? 6  
HELX_P HELX_P28  AD1 PHE A 519 ? ILE A 529 ? PHE A 519 ILE A 529 1 ? 11 
HELX_P HELX_P29  AD2 ILE A 533 ? SER A 559 ? ILE A 533 SER A 559 1 ? 27 
HELX_P HELX_P30  AD3 SER A 592 ? PHE A 603 ? SER A 592 PHE A 603 1 ? 12 
HELX_P HELX_P31  AD4 THR A 604 ? GLY A 606 ? THR A 604 GLY A 606 5 ? 3  
HELX_P HELX_P32  AD5 PHE A 618 ? VAL A 649 ? PHE A 618 VAL A 649 1 ? 32 
HELX_P HELX_P33  AD6 ASN A 655 ? GLU A 672 ? ASN A 655 GLU A 672 1 ? 18 
HELX_P HELX_P34  AD7 ASN A 711 ? LYS A 717 ? ASN A 711 LYS A 717 1 ? 7  
HELX_P HELX_P35  AD8 ASP B 76  ? VAL B 84  ? ASP B 76  VAL B 84  1 ? 9  
HELX_P HELX_P36  AD9 PRO B 89  ? THR B 93  ? PRO B 89  THR B 93  5 ? 5  
HELX_P HELX_P37  AE1 GLY B 94  ? ASN B 102 ? GLY B 94  ASN B 102 1 ? 9  
HELX_P HELX_P38  AE2 ASP B 108 ? THR B 112 ? ASP B 108 THR B 112 5 ? 5  
HELX_P HELX_P39  AE3 THR B 119 ? LEU B 126 ? THR B 119 LEU B 126 1 ? 8  
HELX_P HELX_P40  AE4 CYS B 135 ? SER B 146 ? CYS B 135 SER B 146 1 ? 12 
HELX_P HELX_P41  AE5 LEU B 151 ? ALA B 155 ? LEU B 151 ALA B 155 5 ? 5  
HELX_P HELX_P42  AE6 SER B 166 ? LYS B 174 ? SER B 166 LYS B 174 1 ? 9  
HELX_P HELX_P43  AE7 SER B 176 ? ASN B 186 ? SER B 176 ASN B 186 1 ? 11 
HELX_P HELX_P44  AE8 GLY B 196 ? GLN B 200 ? GLY B 196 GLN B 200 5 ? 5  
HELX_P HELX_P45  AE9 LEU B 212 ? THR B 220 ? LEU B 212 THR B 220 1 ? 9  
HELX_P HELX_P46  AF1 GLN B 222 ? ASN B 232 ? GLN B 222 ASN B 232 1 ? 11 
HELX_P HELX_P47  AF2 THR B 248 ? ALA B 257 ? THR B 248 ALA B 257 1 ? 10 
HELX_P HELX_P48  AF3 SER B 260 ? CYS B 282 ? SER B 260 CYS B 282 1 ? 23 
HELX_P HELX_P49  AF4 GLN B 286 ? ILE B 290 ? GLN B 286 ILE B 290 5 ? 5  
HELX_P HELX_P50  AF5 THR B 297 ? GLU B 305 ? THR B 297 GLU B 305 1 ? 9  
HELX_P HELX_P51  AF6 LYS B 307 ? GLN B 316 ? LYS B 307 GLN B 316 1 ? 10 
HELX_P HELX_P52  AF7 SER B 320 ? SER B 327 ? SER B 320 SER B 327 5 ? 8  
HELX_P HELX_P53  AF8 SER B 355 ? HIS B 363 ? SER B 355 HIS B 363 1 ? 9  
HELX_P HELX_P54  AF9 ASN B 368 ? VAL B 373 ? ASN B 368 VAL B 373 1 ? 6  
HELX_P HELX_P55  AG1 PRO B 377 ? ARG B 388 ? PRO B 377 ARG B 388 1 ? 12 
HELX_P HELX_P56  AG2 LEU B 389 ? HIS B 413 ? LEU B 389 HIS B 413 1 ? 25 
HELX_P HELX_P57  AG3 GLY B 430 ? ARG B 459 ? GLY B 430 ARG B 459 1 ? 30 
HELX_P HELX_P58  AG4 PHE B 462 ? PHE B 467 ? PHE B 462 PHE B 467 1 ? 6  
HELX_P HELX_P59  AG5 TYR B 471 ? MET B 492 ? TYR B 471 MET B 492 1 ? 22 
HELX_P HELX_P60  AG6 TRP B 496 ? LEU B 512 ? TRP B 496 LEU B 512 1 ? 17 
HELX_P HELX_P61  AG7 LEU B 513 ? GLY B 518 ? LEU B 513 GLY B 518 5 ? 6  
HELX_P HELX_P62  AG8 PHE B 519 ? ILE B 529 ? PHE B 519 ILE B 529 1 ? 11 
HELX_P HELX_P63  AG9 ILE B 533 ? SER B 559 ? ILE B 533 SER B 559 1 ? 27 
HELX_P HELX_P64  AH1 SER B 592 ? PHE B 603 ? SER B 592 PHE B 603 1 ? 12 
HELX_P HELX_P65  AH2 THR B 604 ? GLY B 606 ? THR B 604 GLY B 606 5 ? 3  
HELX_P HELX_P66  AH3 PHE B 618 ? VAL B 649 ? PHE B 618 VAL B 649 1 ? 32 
HELX_P HELX_P67  AH4 ASN B 655 ? GLU B 672 ? ASN B 655 GLU B 672 1 ? 18 
HELX_P HELX_P68  AH5 ASN B 711 ? LYS B 717 ? ASN B 711 LYS B 717 1 ? 7  
HELX_P HELX_P69  AH6 ASP C 76  ? VAL C 84  ? ASP C 76  VAL C 84  1 ? 9  
HELX_P HELX_P70  AH7 PRO C 89  ? THR C 93  ? PRO C 89  THR C 93  5 ? 5  
HELX_P HELX_P71  AH8 GLY C 94  ? ASN C 102 ? GLY C 94  ASN C 102 1 ? 9  
HELX_P HELX_P72  AH9 ASP C 108 ? THR C 112 ? ASP C 108 THR C 112 5 ? 5  
HELX_P HELX_P73  AI1 THR C 119 ? LEU C 126 ? THR C 119 LEU C 126 1 ? 8  
HELX_P HELX_P74  AI2 CYS C 135 ? SER C 146 ? CYS C 135 SER C 146 1 ? 12 
HELX_P HELX_P75  AI3 LEU C 151 ? ALA C 155 ? LEU C 151 ALA C 155 5 ? 5  
HELX_P HELX_P76  AI4 SER C 166 ? LYS C 174 ? SER C 166 LYS C 174 1 ? 9  
HELX_P HELX_P77  AI5 SER C 176 ? ASN C 186 ? SER C 176 ASN C 186 1 ? 11 
HELX_P HELX_P78  AI6 GLY C 196 ? GLN C 200 ? GLY C 196 GLN C 200 5 ? 5  
HELX_P HELX_P79  AI7 LEU C 212 ? THR C 220 ? LEU C 212 THR C 220 1 ? 9  
HELX_P HELX_P80  AI8 GLN C 222 ? ASN C 232 ? GLN C 222 ASN C 232 1 ? 11 
HELX_P HELX_P81  AI9 THR C 248 ? ALA C 257 ? THR C 248 ALA C 257 1 ? 10 
HELX_P HELX_P82  AJ1 SER C 260 ? CYS C 282 ? SER C 260 CYS C 282 1 ? 23 
HELX_P HELX_P83  AJ2 GLN C 286 ? ILE C 290 ? GLN C 286 ILE C 290 5 ? 5  
HELX_P HELX_P84  AJ3 THR C 297 ? GLU C 305 ? THR C 297 GLU C 305 1 ? 9  
HELX_P HELX_P85  AJ4 LYS C 307 ? GLN C 316 ? LYS C 307 GLN C 316 1 ? 10 
HELX_P HELX_P86  AJ5 SER C 320 ? SER C 327 ? SER C 320 SER C 327 5 ? 8  
HELX_P HELX_P87  AJ6 SER C 355 ? HIS C 363 ? SER C 355 HIS C 363 1 ? 9  
HELX_P HELX_P88  AJ7 ASN C 368 ? VAL C 373 ? ASN C 368 VAL C 373 1 ? 6  
HELX_P HELX_P89  AJ8 PRO C 377 ? ARG C 388 ? PRO C 377 ARG C 388 1 ? 12 
HELX_P HELX_P90  AJ9 LEU C 389 ? HIS C 413 ? LEU C 389 HIS C 413 1 ? 25 
HELX_P HELX_P91  AK1 GLY C 430 ? ARG C 459 ? GLY C 430 ARG C 459 1 ? 30 
HELX_P HELX_P92  AK2 PHE C 462 ? PHE C 467 ? PHE C 462 PHE C 467 1 ? 6  
HELX_P HELX_P93  AK3 TYR C 471 ? MET C 492 ? TYR C 471 MET C 492 1 ? 22 
HELX_P HELX_P94  AK4 TRP C 496 ? LEU C 512 ? TRP C 496 LEU C 512 1 ? 17 
HELX_P HELX_P95  AK5 LEU C 513 ? GLY C 518 ? LEU C 513 GLY C 518 5 ? 6  
HELX_P HELX_P96  AK6 PHE C 519 ? ILE C 529 ? PHE C 519 ILE C 529 1 ? 11 
HELX_P HELX_P97  AK7 ILE C 533 ? SER C 559 ? ILE C 533 SER C 559 1 ? 27 
HELX_P HELX_P98  AK8 SER C 592 ? PHE C 603 ? SER C 592 PHE C 603 1 ? 12 
HELX_P HELX_P99  AK9 THR C 604 ? GLY C 606 ? THR C 604 GLY C 606 5 ? 3  
HELX_P HELX_P100 AL1 PHE C 618 ? VAL C 649 ? PHE C 618 VAL C 649 1 ? 32 
HELX_P HELX_P101 AL2 ASN C 655 ? GLU C 672 ? ASN C 655 GLU C 672 1 ? 18 
HELX_P HELX_P102 AL3 ASN C 711 ? LYS C 717 ? ASN C 711 LYS C 717 1 ? 7  
HELX_P HELX_P103 AL4 ASP D 76  ? VAL D 84  ? ASP D 76  VAL D 84  1 ? 9  
HELX_P HELX_P104 AL5 PRO D 89  ? THR D 93  ? PRO D 89  THR D 93  5 ? 5  
HELX_P HELX_P105 AL6 GLY D 94  ? ASN D 102 ? GLY D 94  ASN D 102 1 ? 9  
HELX_P HELX_P106 AL7 ASP D 108 ? THR D 112 ? ASP D 108 THR D 112 5 ? 5  
HELX_P HELX_P107 AL8 THR D 119 ? LEU D 126 ? THR D 119 LEU D 126 1 ? 8  
HELX_P HELX_P108 AL9 CYS D 135 ? SER D 146 ? CYS D 135 SER D 146 1 ? 12 
HELX_P HELX_P109 AM1 LEU D 151 ? ALA D 155 ? LEU D 151 ALA D 155 5 ? 5  
HELX_P HELX_P110 AM2 SER D 166 ? LYS D 174 ? SER D 166 LYS D 174 1 ? 9  
HELX_P HELX_P111 AM3 SER D 176 ? ASN D 186 ? SER D 176 ASN D 186 1 ? 11 
HELX_P HELX_P112 AM4 GLY D 196 ? GLN D 200 ? GLY D 196 GLN D 200 5 ? 5  
HELX_P HELX_P113 AM5 LEU D 212 ? THR D 220 ? LEU D 212 THR D 220 1 ? 9  
HELX_P HELX_P114 AM6 GLN D 222 ? ASN D 232 ? GLN D 222 ASN D 232 1 ? 11 
HELX_P HELX_P115 AM7 THR D 248 ? ALA D 257 ? THR D 248 ALA D 257 1 ? 10 
HELX_P HELX_P116 AM8 SER D 260 ? CYS D 282 ? SER D 260 CYS D 282 1 ? 23 
HELX_P HELX_P117 AM9 GLN D 286 ? ILE D 290 ? GLN D 286 ILE D 290 5 ? 5  
HELX_P HELX_P118 AN1 THR D 297 ? GLU D 305 ? THR D 297 GLU D 305 1 ? 9  
HELX_P HELX_P119 AN2 LYS D 307 ? GLN D 316 ? LYS D 307 GLN D 316 1 ? 10 
HELX_P HELX_P120 AN3 SER D 320 ? SER D 327 ? SER D 320 SER D 327 5 ? 8  
HELX_P HELX_P121 AN4 SER D 355 ? HIS D 363 ? SER D 355 HIS D 363 1 ? 9  
HELX_P HELX_P122 AN5 ASN D 368 ? VAL D 373 ? ASN D 368 VAL D 373 1 ? 6  
HELX_P HELX_P123 AN6 PRO D 377 ? ARG D 388 ? PRO D 377 ARG D 388 1 ? 12 
HELX_P HELX_P124 AN7 LEU D 389 ? HIS D 413 ? LEU D 389 HIS D 413 1 ? 25 
HELX_P HELX_P125 AN8 GLY D 430 ? ARG D 459 ? GLY D 430 ARG D 459 1 ? 30 
HELX_P HELX_P126 AN9 PHE D 462 ? PHE D 467 ? PHE D 462 PHE D 467 1 ? 6  
HELX_P HELX_P127 AO1 TYR D 471 ? MET D 492 ? TYR D 471 MET D 492 1 ? 22 
HELX_P HELX_P128 AO2 TRP D 496 ? LEU D 512 ? TRP D 496 LEU D 512 1 ? 17 
HELX_P HELX_P129 AO3 LEU D 513 ? GLY D 518 ? LEU D 513 GLY D 518 5 ? 6  
HELX_P HELX_P130 AO4 PHE D 519 ? ILE D 529 ? PHE D 519 ILE D 529 1 ? 11 
HELX_P HELX_P131 AO5 ILE D 533 ? SER D 559 ? ILE D 533 SER D 559 1 ? 27 
HELX_P HELX_P132 AO6 SER D 592 ? PHE D 603 ? SER D 592 PHE D 603 1 ? 12 
HELX_P HELX_P133 AO7 THR D 604 ? GLY D 606 ? THR D 604 GLY D 606 5 ? 3  
HELX_P HELX_P134 AO8 PHE D 618 ? VAL D 649 ? PHE D 618 VAL D 649 1 ? 32 
HELX_P HELX_P135 AO9 ASN D 655 ? GLU D 672 ? ASN D 655 GLU D 672 1 ? 18 
HELX_P HELX_P136 AP1 ASN D 711 ? LYS D 717 ? ASN D 711 LYS D 717 1 ? 7  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 GLU 376 A . ? GLU 376 A PRO 377 A ? PRO 377 A 1 -2.64 
2 GLU 376 B . ? GLU 376 B PRO 377 B ? PRO 377 B 1 -2.64 
3 GLU 376 C . ? GLU 376 C PRO 377 C ? PRO 377 C 1 -2.64 
4 GLU 376 D . ? GLU 376 D PRO 377 D ? PRO 377 D 1 -2.64 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 4 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LYS A 329 ? TYR A 335 ? LYS A 329 TYR A 335 
AA1 2 VAL A 338 ? ASP A 344 ? VAL A 338 ASP A 344 
AA1 3 ASP A 700 ? VAL A 710 ? ASP A 700 VAL A 710 
AA1 4 ARG A 687 ? GLY A 692 ? ARG A 687 GLY A 692 
AA2 1 LYS B 329 ? TYR B 335 ? LYS B 329 TYR B 335 
AA2 2 VAL B 338 ? ASP B 344 ? VAL B 338 ASP B 344 
AA2 3 ASP B 700 ? VAL B 710 ? ASP B 700 VAL B 710 
AA2 4 ARG B 687 ? GLY B 692 ? ARG B 687 GLY B 692 
AA3 1 LYS C 329 ? TYR C 335 ? LYS C 329 TYR C 335 
AA3 2 VAL C 338 ? ASP C 344 ? VAL C 338 ASP C 344 
AA3 3 ASP C 700 ? VAL C 710 ? ASP C 700 VAL C 710 
AA3 4 ARG C 687 ? GLY C 692 ? ARG C 687 GLY C 692 
AA4 1 LYS D 329 ? TYR D 335 ? LYS D 329 TYR D 335 
AA4 2 VAL D 338 ? ASP D 344 ? VAL D 338 ASP D 344 
AA4 3 ASP D 700 ? VAL D 710 ? ASP D 700 VAL D 710 
AA4 4 ARG D 687 ? GLY D 692 ? ARG D 687 GLY D 692 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N GLU A 332 ? N GLU A 332 O VAL A 340 ? O VAL A 340 
AA1 2 3 N ARG A 339 ? N ARG A 339 O GLU A 709 ? O GLU A 709 
AA1 3 4 O ASP A 700 ? O ASP A 700 N VAL A 691 ? N VAL A 691 
AA2 1 2 N GLU B 332 ? N GLU B 332 O VAL B 340 ? O VAL B 340 
AA2 2 3 N ARG B 339 ? N ARG B 339 O GLU B 709 ? O GLU B 709 
AA2 3 4 O ASP B 700 ? O ASP B 700 N VAL B 691 ? N VAL B 691 
AA3 1 2 N GLU C 332 ? N GLU C 332 O VAL C 340 ? O VAL C 340 
AA3 2 3 N ARG C 339 ? N ARG C 339 O GLU C 709 ? O GLU C 709 
AA3 3 4 O ASP C 700 ? O ASP C 700 N VAL C 691 ? N VAL C 691 
AA4 1 2 N GLU D 332 ? N GLU D 332 O VAL D 340 ? O VAL D 340 
AA4 2 3 N ARG D 339 ? N ARG D 339 O GLU D 709 ? O GLU D 709 
AA4 3 4 O ASP D 700 ? O ASP D 700 N VAL D 691 ? N VAL D 691 
# 
_pdbx_entry_details.entry_id                   9B3U 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ASN A 127 ? ? 56.29   76.00 
2  1 LYS A 150 ? ? -101.02 78.82 
3  1 ALA A 194 ? ? -62.48  96.49 
4  1 PHE A 209 ? ? -140.98 23.93 
5  1 CYS A 282 ? ? -145.13 59.83 
6  1 VAL A 649 ? ? -109.54 62.26 
7  1 HIS A 651 ? ? 59.52   18.86 
8  1 ARG A 679 ? ? 39.87   75.05 
9  1 ASN B 127 ? ? 56.29   76.00 
10 1 LYS B 150 ? ? -101.02 78.82 
11 1 ALA B 194 ? ? -62.48  96.49 
12 1 PHE B 209 ? ? -140.98 23.93 
13 1 CYS B 282 ? ? -145.13 59.83 
14 1 VAL B 649 ? ? -109.54 62.26 
15 1 HIS B 651 ? ? 59.52   18.86 
16 1 ARG B 679 ? ? 39.87   75.05 
17 1 ASN C 127 ? ? 56.29   76.00 
18 1 LYS C 150 ? ? -101.02 78.82 
19 1 ALA C 194 ? ? -62.48  96.49 
20 1 PHE C 209 ? ? -140.98 23.93 
21 1 CYS C 282 ? ? -145.13 59.83 
22 1 VAL C 649 ? ? -109.54 62.26 
23 1 HIS C 651 ? ? 59.52   18.86 
24 1 ARG C 679 ? ? 39.87   75.05 
25 1 ASN D 127 ? ? 56.29   76.00 
26 1 LYS D 150 ? ? -101.02 78.82 
27 1 ALA D 194 ? ? -62.48  96.49 
28 1 PHE D 209 ? ? -140.98 23.93 
29 1 CYS D 282 ? ? -145.13 59.83 
30 1 VAL D 649 ? ? -109.54 62.26 
31 1 HIS D 651 ? ? 59.52   18.86 
32 1 ARG D 679 ? ? 39.87   75.05 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9B3U 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9B3U 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.4 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               242931 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Homotetramer of rat TRPV2 WT' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9B3U 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             500 
_em_imaging.nominal_defocus_max             2500 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9B3U 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9B3U 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              9B3U 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        C4 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A THR 2   ? A THR 2   
3   1 Y 1 A SER 3   ? A SER 3   
4   1 Y 1 A ALA 4   ? A ALA 4   
5   1 Y 1 A SER 5   ? A SER 5   
6   1 Y 1 A SER 6   ? A SER 6   
7   1 Y 1 A PRO 7   ? A PRO 7   
8   1 Y 1 A PRO 8   ? A PRO 8   
9   1 Y 1 A ALA 9   ? A ALA 9   
10  1 Y 1 A PHE 10  ? A PHE 10  
11  1 Y 1 A ARG 11  ? A ARG 11  
12  1 Y 1 A LEU 12  ? A LEU 12  
13  1 Y 1 A GLU 13  ? A GLU 13  
14  1 Y 1 A THR 14  ? A THR 14  
15  1 Y 1 A SER 15  ? A SER 15  
16  1 Y 1 A ASP 16  ? A ASP 16  
17  1 Y 1 A GLY 17  ? A GLY 17  
18  1 Y 1 A ASP 18  ? A ASP 18  
19  1 Y 1 A GLU 19  ? A GLU 19  
20  1 Y 1 A GLU 20  ? A GLU 20  
21  1 Y 1 A GLY 21  ? A GLY 21  
22  1 Y 1 A ASN 22  ? A ASN 22  
23  1 Y 1 A ALA 23  ? A ALA 23  
24  1 Y 1 A GLU 24  ? A GLU 24  
25  1 Y 1 A VAL 25  ? A VAL 25  
26  1 Y 1 A ASN 26  ? A ASN 26  
27  1 Y 1 A LYS 27  ? A LYS 27  
28  1 Y 1 A GLY 28  ? A GLY 28  
29  1 Y 1 A LYS 29  ? A LYS 29  
30  1 Y 1 A GLN 30  ? A GLN 30  
31  1 Y 1 A GLU 31  ? A GLU 31  
32  1 Y 1 A PRO 32  ? A PRO 32  
33  1 Y 1 A PRO 33  ? A PRO 33  
34  1 Y 1 A PRO 34  ? A PRO 34  
35  1 Y 1 A MET 35  ? A MET 35  
36  1 Y 1 A GLU 36  ? A GLU 36  
37  1 Y 1 A SER 37  ? A SER 37  
38  1 Y 1 A PRO 38  ? A PRO 38  
39  1 Y 1 A PHE 39  ? A PHE 39  
40  1 Y 1 A GLN 40  ? A GLN 40  
41  1 Y 1 A ARG 41  ? A ARG 41  
42  1 Y 1 A GLU 42  ? A GLU 42  
43  1 Y 1 A ASP 43  ? A ASP 43  
44  1 Y 1 A ARG 44  ? A ARG 44  
45  1 Y 1 A ASN 45  ? A ASN 45  
46  1 Y 1 A SER 46  ? A SER 46  
47  1 Y 1 A SER 47  ? A SER 47  
48  1 Y 1 A PRO 48  ? A PRO 48  
49  1 Y 1 A GLN 49  ? A GLN 49  
50  1 Y 1 A ILE 50  ? A ILE 50  
51  1 Y 1 A LYS 51  ? A LYS 51  
52  1 Y 1 A VAL 52  ? A VAL 52  
53  1 Y 1 A ASN 53  ? A ASN 53  
54  1 Y 1 A LEU 54  ? A LEU 54  
55  1 Y 1 A ASN 55  ? A ASN 55  
56  1 Y 1 A PHE 56  ? A PHE 56  
57  1 Y 1 A ILE 57  ? A ILE 57  
58  1 Y 1 A LYS 58  ? A LYS 58  
59  1 Y 1 A ARG 59  ? A ARG 59  
60  1 Y 1 A PRO 60  ? A PRO 60  
61  1 Y 1 A PRO 61  ? A PRO 61  
62  1 Y 1 A LYS 62  ? A LYS 62  
63  1 Y 1 A ASN 63  ? A ASN 63  
64  1 Y 1 A THR 64  ? A THR 64  
65  1 Y 1 A SER 65  ? A SER 65  
66  1 Y 1 A ALA 66  ? A ALA 66  
67  1 Y 1 A PRO 67  ? A PRO 67  
68  1 Y 1 A SER 68  ? A SER 68  
69  1 Y 1 A GLN 69  ? A GLN 69  
70  1 Y 1 A GLN 70  ? A GLN 70  
71  1 Y 1 A GLU 71  ? A GLU 71  
72  1 Y 1 A PRO 72  ? A PRO 72  
73  1 Y 1 A ASP 73  ? A ASP 73  
74  1 Y 1 A ASP 418 ? A ASP 418 
75  1 Y 1 A GLN 419 ? A GLN 419 
76  1 Y 1 A PRO 420 ? A PRO 420 
77  1 Y 1 A ALA 421 ? A ALA 421 
78  1 Y 1 A ILE 422 ? A ILE 422 
79  1 Y 1 A PRO 423 ? A PRO 423 
80  1 Y 1 A SER 424 ? A SER 424 
81  1 Y 1 A SER 425 ? A SER 425 
82  1 Y 1 A LYS 426 ? A LYS 426 
83  1 Y 1 A ALA 427 ? A ALA 427 
84  1 Y 1 A THR 428 ? A THR 428 
85  1 Y 1 A SER 564 ? A SER 564 
86  1 Y 1 A PRO 565 ? A PRO 565 
87  1 Y 1 A LYS 566 ? A LYS 566 
88  1 Y 1 A ALA 567 ? A ALA 567 
89  1 Y 1 A PRO 568 ? A PRO 568 
90  1 Y 1 A GLU 569 ? A GLU 569 
91  1 Y 1 A ASP 570 ? A ASP 570 
92  1 Y 1 A ASN 571 ? A ASN 571 
93  1 Y 1 A ASN 572 ? A ASN 572 
94  1 Y 1 A SER 573 ? A SER 573 
95  1 Y 1 A THR 574 ? A THR 574 
96  1 Y 1 A VAL 575 ? A VAL 575 
97  1 Y 1 A THR 576 ? A THR 576 
98  1 Y 1 A GLU 577 ? A GLU 577 
99  1 Y 1 A GLN 578 ? A GLN 578 
100 1 Y 1 A PRO 579 ? A PRO 579 
101 1 Y 1 A THR 580 ? A THR 580 
102 1 Y 1 A VAL 581 ? A VAL 581 
103 1 Y 1 A GLY 582 ? A GLY 582 
104 1 Y 1 A GLN 583 ? A GLN 583 
105 1 Y 1 A GLU 584 ? A GLU 584 
106 1 Y 1 A GLU 585 ? A GLU 585 
107 1 Y 1 A GLU 586 ? A GLU 586 
108 1 Y 1 A PRO 587 ? A PRO 587 
109 1 Y 1 A ALA 588 ? A ALA 588 
110 1 Y 1 A GLY 695 ? A GLY 695 
111 1 Y 1 A ASP 696 ? A ASP 696 
112 1 Y 1 A GLY 697 ? A GLY 697 
113 1 Y 1 A THR 698 ? A THR 698 
114 1 Y 1 A PRO 720 ? A PRO 720 
115 1 Y 1 A THR 721 ? A THR 721 
116 1 Y 1 A LEU 722 ? A LEU 722 
117 1 Y 1 A SER 723 ? A SER 723 
118 1 Y 1 A GLU 724 ? A GLU 724 
119 1 Y 1 A ASP 725 ? A ASP 725 
120 1 Y 1 A PRO 726 ? A PRO 726 
121 1 Y 1 A SER 727 ? A SER 727 
122 1 Y 1 A GLY 728 ? A GLY 728 
123 1 Y 1 A PRO 729 ? A PRO 729 
124 1 Y 1 A GLY 730 ? A GLY 730 
125 1 Y 1 A ILE 731 ? A ILE 731 
126 1 Y 1 A THR 732 ? A THR 732 
127 1 Y 1 A GLY 733 ? A GLY 733 
128 1 Y 1 A ASN 734 ? A ASN 734 
129 1 Y 1 A LYS 735 ? A LYS 735 
130 1 Y 1 A LYS 736 ? A LYS 736 
131 1 Y 1 A ASN 737 ? A ASN 737 
132 1 Y 1 A PRO 738 ? A PRO 738 
133 1 Y 1 A THR 739 ? A THR 739 
134 1 Y 1 A SER 740 ? A SER 740 
135 1 Y 1 A LYS 741 ? A LYS 741 
136 1 Y 1 A PRO 742 ? A PRO 742 
137 1 Y 1 A GLY 743 ? A GLY 743 
138 1 Y 1 A LYS 744 ? A LYS 744 
139 1 Y 1 A ASN 745 ? A ASN 745 
140 1 Y 1 A SER 746 ? A SER 746 
141 1 Y 1 A ALA 747 ? A ALA 747 
142 1 Y 1 A SER 748 ? A SER 748 
143 1 Y 1 A GLU 749 ? A GLU 749 
144 1 Y 1 A GLU 750 ? A GLU 750 
145 1 Y 1 A ASP 751 ? A ASP 751 
146 1 Y 1 A HIS 752 ? A HIS 752 
147 1 Y 1 A LEU 753 ? A LEU 753 
148 1 Y 1 A PRO 754 ? A PRO 754 
149 1 Y 1 A LEU 755 ? A LEU 755 
150 1 Y 1 A GLN 756 ? A GLN 756 
151 1 Y 1 A VAL 757 ? A VAL 757 
152 1 Y 1 A LEU 758 ? A LEU 758 
153 1 Y 1 A GLN 759 ? A GLN 759 
154 1 Y 1 A SER 760 ? A SER 760 
155 1 Y 1 A PRO 761 ? A PRO 761 
156 1 Y 1 B MET 1   ? B MET 1   
157 1 Y 1 B THR 2   ? B THR 2   
158 1 Y 1 B SER 3   ? B SER 3   
159 1 Y 1 B ALA 4   ? B ALA 4   
160 1 Y 1 B SER 5   ? B SER 5   
161 1 Y 1 B SER 6   ? B SER 6   
162 1 Y 1 B PRO 7   ? B PRO 7   
163 1 Y 1 B PRO 8   ? B PRO 8   
164 1 Y 1 B ALA 9   ? B ALA 9   
165 1 Y 1 B PHE 10  ? B PHE 10  
166 1 Y 1 B ARG 11  ? B ARG 11  
167 1 Y 1 B LEU 12  ? B LEU 12  
168 1 Y 1 B GLU 13  ? B GLU 13  
169 1 Y 1 B THR 14  ? B THR 14  
170 1 Y 1 B SER 15  ? B SER 15  
171 1 Y 1 B ASP 16  ? B ASP 16  
172 1 Y 1 B GLY 17  ? B GLY 17  
173 1 Y 1 B ASP 18  ? B ASP 18  
174 1 Y 1 B GLU 19  ? B GLU 19  
175 1 Y 1 B GLU 20  ? B GLU 20  
176 1 Y 1 B GLY 21  ? B GLY 21  
177 1 Y 1 B ASN 22  ? B ASN 22  
178 1 Y 1 B ALA 23  ? B ALA 23  
179 1 Y 1 B GLU 24  ? B GLU 24  
180 1 Y 1 B VAL 25  ? B VAL 25  
181 1 Y 1 B ASN 26  ? B ASN 26  
182 1 Y 1 B LYS 27  ? B LYS 27  
183 1 Y 1 B GLY 28  ? B GLY 28  
184 1 Y 1 B LYS 29  ? B LYS 29  
185 1 Y 1 B GLN 30  ? B GLN 30  
186 1 Y 1 B GLU 31  ? B GLU 31  
187 1 Y 1 B PRO 32  ? B PRO 32  
188 1 Y 1 B PRO 33  ? B PRO 33  
189 1 Y 1 B PRO 34  ? B PRO 34  
190 1 Y 1 B MET 35  ? B MET 35  
191 1 Y 1 B GLU 36  ? B GLU 36  
192 1 Y 1 B SER 37  ? B SER 37  
193 1 Y 1 B PRO 38  ? B PRO 38  
194 1 Y 1 B PHE 39  ? B PHE 39  
195 1 Y 1 B GLN 40  ? B GLN 40  
196 1 Y 1 B ARG 41  ? B ARG 41  
197 1 Y 1 B GLU 42  ? B GLU 42  
198 1 Y 1 B ASP 43  ? B ASP 43  
199 1 Y 1 B ARG 44  ? B ARG 44  
200 1 Y 1 B ASN 45  ? B ASN 45  
201 1 Y 1 B SER 46  ? B SER 46  
202 1 Y 1 B SER 47  ? B SER 47  
203 1 Y 1 B PRO 48  ? B PRO 48  
204 1 Y 1 B GLN 49  ? B GLN 49  
205 1 Y 1 B ILE 50  ? B ILE 50  
206 1 Y 1 B LYS 51  ? B LYS 51  
207 1 Y 1 B VAL 52  ? B VAL 52  
208 1 Y 1 B ASN 53  ? B ASN 53  
209 1 Y 1 B LEU 54  ? B LEU 54  
210 1 Y 1 B ASN 55  ? B ASN 55  
211 1 Y 1 B PHE 56  ? B PHE 56  
212 1 Y 1 B ILE 57  ? B ILE 57  
213 1 Y 1 B LYS 58  ? B LYS 58  
214 1 Y 1 B ARG 59  ? B ARG 59  
215 1 Y 1 B PRO 60  ? B PRO 60  
216 1 Y 1 B PRO 61  ? B PRO 61  
217 1 Y 1 B LYS 62  ? B LYS 62  
218 1 Y 1 B ASN 63  ? B ASN 63  
219 1 Y 1 B THR 64  ? B THR 64  
220 1 Y 1 B SER 65  ? B SER 65  
221 1 Y 1 B ALA 66  ? B ALA 66  
222 1 Y 1 B PRO 67  ? B PRO 67  
223 1 Y 1 B SER 68  ? B SER 68  
224 1 Y 1 B GLN 69  ? B GLN 69  
225 1 Y 1 B GLN 70  ? B GLN 70  
226 1 Y 1 B GLU 71  ? B GLU 71  
227 1 Y 1 B PRO 72  ? B PRO 72  
228 1 Y 1 B ASP 73  ? B ASP 73  
229 1 Y 1 B ASP 418 ? B ASP 418 
230 1 Y 1 B GLN 419 ? B GLN 419 
231 1 Y 1 B PRO 420 ? B PRO 420 
232 1 Y 1 B ALA 421 ? B ALA 421 
233 1 Y 1 B ILE 422 ? B ILE 422 
234 1 Y 1 B PRO 423 ? B PRO 423 
235 1 Y 1 B SER 424 ? B SER 424 
236 1 Y 1 B SER 425 ? B SER 425 
237 1 Y 1 B LYS 426 ? B LYS 426 
238 1 Y 1 B ALA 427 ? B ALA 427 
239 1 Y 1 B THR 428 ? B THR 428 
240 1 Y 1 B SER 564 ? B SER 564 
241 1 Y 1 B PRO 565 ? B PRO 565 
242 1 Y 1 B LYS 566 ? B LYS 566 
243 1 Y 1 B ALA 567 ? B ALA 567 
244 1 Y 1 B PRO 568 ? B PRO 568 
245 1 Y 1 B GLU 569 ? B GLU 569 
246 1 Y 1 B ASP 570 ? B ASP 570 
247 1 Y 1 B ASN 571 ? B ASN 571 
248 1 Y 1 B ASN 572 ? B ASN 572 
249 1 Y 1 B SER 573 ? B SER 573 
250 1 Y 1 B THR 574 ? B THR 574 
251 1 Y 1 B VAL 575 ? B VAL 575 
252 1 Y 1 B THR 576 ? B THR 576 
253 1 Y 1 B GLU 577 ? B GLU 577 
254 1 Y 1 B GLN 578 ? B GLN 578 
255 1 Y 1 B PRO 579 ? B PRO 579 
256 1 Y 1 B THR 580 ? B THR 580 
257 1 Y 1 B VAL 581 ? B VAL 581 
258 1 Y 1 B GLY 582 ? B GLY 582 
259 1 Y 1 B GLN 583 ? B GLN 583 
260 1 Y 1 B GLU 584 ? B GLU 584 
261 1 Y 1 B GLU 585 ? B GLU 585 
262 1 Y 1 B GLU 586 ? B GLU 586 
263 1 Y 1 B PRO 587 ? B PRO 587 
264 1 Y 1 B ALA 588 ? B ALA 588 
265 1 Y 1 B ASP 696 ? B ASP 696 
266 1 Y 1 B GLY 697 ? B GLY 697 
267 1 Y 1 B THR 698 ? B THR 698 
268 1 Y 1 B PRO 720 ? B PRO 720 
269 1 Y 1 B THR 721 ? B THR 721 
270 1 Y 1 B LEU 722 ? B LEU 722 
271 1 Y 1 B SER 723 ? B SER 723 
272 1 Y 1 B GLU 724 ? B GLU 724 
273 1 Y 1 B ASP 725 ? B ASP 725 
274 1 Y 1 B PRO 726 ? B PRO 726 
275 1 Y 1 B SER 727 ? B SER 727 
276 1 Y 1 B GLY 728 ? B GLY 728 
277 1 Y 1 B PRO 729 ? B PRO 729 
278 1 Y 1 B GLY 730 ? B GLY 730 
279 1 Y 1 B ILE 731 ? B ILE 731 
280 1 Y 1 B THR 732 ? B THR 732 
281 1 Y 1 B GLY 733 ? B GLY 733 
282 1 Y 1 B ASN 734 ? B ASN 734 
283 1 Y 1 B LYS 735 ? B LYS 735 
284 1 Y 1 B LYS 736 ? B LYS 736 
285 1 Y 1 B ASN 737 ? B ASN 737 
286 1 Y 1 B PRO 738 ? B PRO 738 
287 1 Y 1 B THR 739 ? B THR 739 
288 1 Y 1 B SER 740 ? B SER 740 
289 1 Y 1 B LYS 741 ? B LYS 741 
290 1 Y 1 B PRO 742 ? B PRO 742 
291 1 Y 1 B GLY 743 ? B GLY 743 
292 1 Y 1 B LYS 744 ? B LYS 744 
293 1 Y 1 B ASN 745 ? B ASN 745 
294 1 Y 1 B SER 746 ? B SER 746 
295 1 Y 1 B ALA 747 ? B ALA 747 
296 1 Y 1 B SER 748 ? B SER 748 
297 1 Y 1 B GLU 749 ? B GLU 749 
298 1 Y 1 B GLU 750 ? B GLU 750 
299 1 Y 1 B ASP 751 ? B ASP 751 
300 1 Y 1 B HIS 752 ? B HIS 752 
301 1 Y 1 B LEU 753 ? B LEU 753 
302 1 Y 1 B PRO 754 ? B PRO 754 
303 1 Y 1 B LEU 755 ? B LEU 755 
304 1 Y 1 B GLN 756 ? B GLN 756 
305 1 Y 1 B VAL 757 ? B VAL 757 
306 1 Y 1 B LEU 758 ? B LEU 758 
307 1 Y 1 B GLN 759 ? B GLN 759 
308 1 Y 1 B SER 760 ? B SER 760 
309 1 Y 1 B PRO 761 ? B PRO 761 
310 1 Y 1 C MET 1   ? C MET 1   
311 1 Y 1 C THR 2   ? C THR 2   
312 1 Y 1 C SER 3   ? C SER 3   
313 1 Y 1 C ALA 4   ? C ALA 4   
314 1 Y 1 C SER 5   ? C SER 5   
315 1 Y 1 C SER 6   ? C SER 6   
316 1 Y 1 C PRO 7   ? C PRO 7   
317 1 Y 1 C PRO 8   ? C PRO 8   
318 1 Y 1 C ALA 9   ? C ALA 9   
319 1 Y 1 C PHE 10  ? C PHE 10  
320 1 Y 1 C ARG 11  ? C ARG 11  
321 1 Y 1 C LEU 12  ? C LEU 12  
322 1 Y 1 C GLU 13  ? C GLU 13  
323 1 Y 1 C THR 14  ? C THR 14  
324 1 Y 1 C SER 15  ? C SER 15  
325 1 Y 1 C ASP 16  ? C ASP 16  
326 1 Y 1 C GLY 17  ? C GLY 17  
327 1 Y 1 C ASP 18  ? C ASP 18  
328 1 Y 1 C GLU 19  ? C GLU 19  
329 1 Y 1 C GLU 20  ? C GLU 20  
330 1 Y 1 C GLY 21  ? C GLY 21  
331 1 Y 1 C ASN 22  ? C ASN 22  
332 1 Y 1 C ALA 23  ? C ALA 23  
333 1 Y 1 C GLU 24  ? C GLU 24  
334 1 Y 1 C VAL 25  ? C VAL 25  
335 1 Y 1 C ASN 26  ? C ASN 26  
336 1 Y 1 C LYS 27  ? C LYS 27  
337 1 Y 1 C GLY 28  ? C GLY 28  
338 1 Y 1 C LYS 29  ? C LYS 29  
339 1 Y 1 C GLN 30  ? C GLN 30  
340 1 Y 1 C GLU 31  ? C GLU 31  
341 1 Y 1 C PRO 32  ? C PRO 32  
342 1 Y 1 C PRO 33  ? C PRO 33  
343 1 Y 1 C PRO 34  ? C PRO 34  
344 1 Y 1 C MET 35  ? C MET 35  
345 1 Y 1 C GLU 36  ? C GLU 36  
346 1 Y 1 C SER 37  ? C SER 37  
347 1 Y 1 C PRO 38  ? C PRO 38  
348 1 Y 1 C PHE 39  ? C PHE 39  
349 1 Y 1 C GLN 40  ? C GLN 40  
350 1 Y 1 C ARG 41  ? C ARG 41  
351 1 Y 1 C GLU 42  ? C GLU 42  
352 1 Y 1 C ASP 43  ? C ASP 43  
353 1 Y 1 C ARG 44  ? C ARG 44  
354 1 Y 1 C ASN 45  ? C ASN 45  
355 1 Y 1 C SER 46  ? C SER 46  
356 1 Y 1 C SER 47  ? C SER 47  
357 1 Y 1 C PRO 48  ? C PRO 48  
358 1 Y 1 C GLN 49  ? C GLN 49  
359 1 Y 1 C ILE 50  ? C ILE 50  
360 1 Y 1 C LYS 51  ? C LYS 51  
361 1 Y 1 C VAL 52  ? C VAL 52  
362 1 Y 1 C ASN 53  ? C ASN 53  
363 1 Y 1 C LEU 54  ? C LEU 54  
364 1 Y 1 C ASN 55  ? C ASN 55  
365 1 Y 1 C PHE 56  ? C PHE 56  
366 1 Y 1 C ILE 57  ? C ILE 57  
367 1 Y 1 C LYS 58  ? C LYS 58  
368 1 Y 1 C ARG 59  ? C ARG 59  
369 1 Y 1 C PRO 60  ? C PRO 60  
370 1 Y 1 C PRO 61  ? C PRO 61  
371 1 Y 1 C LYS 62  ? C LYS 62  
372 1 Y 1 C ASN 63  ? C ASN 63  
373 1 Y 1 C THR 64  ? C THR 64  
374 1 Y 1 C SER 65  ? C SER 65  
375 1 Y 1 C ALA 66  ? C ALA 66  
376 1 Y 1 C PRO 67  ? C PRO 67  
377 1 Y 1 C SER 68  ? C SER 68  
378 1 Y 1 C GLN 69  ? C GLN 69  
379 1 Y 1 C GLN 70  ? C GLN 70  
380 1 Y 1 C GLU 71  ? C GLU 71  
381 1 Y 1 C PRO 72  ? C PRO 72  
382 1 Y 1 C ASP 73  ? C ASP 73  
383 1 Y 1 C ASP 418 ? C ASP 418 
384 1 Y 1 C GLN 419 ? C GLN 419 
385 1 Y 1 C PRO 420 ? C PRO 420 
386 1 Y 1 C ALA 421 ? C ALA 421 
387 1 Y 1 C ILE 422 ? C ILE 422 
388 1 Y 1 C PRO 423 ? C PRO 423 
389 1 Y 1 C SER 424 ? C SER 424 
390 1 Y 1 C SER 425 ? C SER 425 
391 1 Y 1 C LYS 426 ? C LYS 426 
392 1 Y 1 C ALA 427 ? C ALA 427 
393 1 Y 1 C THR 428 ? C THR 428 
394 1 Y 1 C SER 564 ? C SER 564 
395 1 Y 1 C PRO 565 ? C PRO 565 
396 1 Y 1 C LYS 566 ? C LYS 566 
397 1 Y 1 C ALA 567 ? C ALA 567 
398 1 Y 1 C PRO 568 ? C PRO 568 
399 1 Y 1 C GLU 569 ? C GLU 569 
400 1 Y 1 C ASP 570 ? C ASP 570 
401 1 Y 1 C ASN 571 ? C ASN 571 
402 1 Y 1 C ASN 572 ? C ASN 572 
403 1 Y 1 C SER 573 ? C SER 573 
404 1 Y 1 C THR 574 ? C THR 574 
405 1 Y 1 C VAL 575 ? C VAL 575 
406 1 Y 1 C THR 576 ? C THR 576 
407 1 Y 1 C GLU 577 ? C GLU 577 
408 1 Y 1 C GLN 578 ? C GLN 578 
409 1 Y 1 C PRO 579 ? C PRO 579 
410 1 Y 1 C THR 580 ? C THR 580 
411 1 Y 1 C VAL 581 ? C VAL 581 
412 1 Y 1 C GLY 582 ? C GLY 582 
413 1 Y 1 C GLN 583 ? C GLN 583 
414 1 Y 1 C GLU 584 ? C GLU 584 
415 1 Y 1 C GLU 585 ? C GLU 585 
416 1 Y 1 C GLU 586 ? C GLU 586 
417 1 Y 1 C PRO 587 ? C PRO 587 
418 1 Y 1 C ALA 588 ? C ALA 588 
419 1 Y 1 C ASP 696 ? C ASP 696 
420 1 Y 1 C GLY 697 ? C GLY 697 
421 1 Y 1 C THR 698 ? C THR 698 
422 1 Y 1 C PRO 720 ? C PRO 720 
423 1 Y 1 C THR 721 ? C THR 721 
424 1 Y 1 C LEU 722 ? C LEU 722 
425 1 Y 1 C SER 723 ? C SER 723 
426 1 Y 1 C GLU 724 ? C GLU 724 
427 1 Y 1 C ASP 725 ? C ASP 725 
428 1 Y 1 C PRO 726 ? C PRO 726 
429 1 Y 1 C SER 727 ? C SER 727 
430 1 Y 1 C GLY 728 ? C GLY 728 
431 1 Y 1 C PRO 729 ? C PRO 729 
432 1 Y 1 C GLY 730 ? C GLY 730 
433 1 Y 1 C ILE 731 ? C ILE 731 
434 1 Y 1 C THR 732 ? C THR 732 
435 1 Y 1 C GLY 733 ? C GLY 733 
436 1 Y 1 C ASN 734 ? C ASN 734 
437 1 Y 1 C LYS 735 ? C LYS 735 
438 1 Y 1 C LYS 736 ? C LYS 736 
439 1 Y 1 C ASN 737 ? C ASN 737 
440 1 Y 1 C PRO 738 ? C PRO 738 
441 1 Y 1 C THR 739 ? C THR 739 
442 1 Y 1 C SER 740 ? C SER 740 
443 1 Y 1 C LYS 741 ? C LYS 741 
444 1 Y 1 C PRO 742 ? C PRO 742 
445 1 Y 1 C GLY 743 ? C GLY 743 
446 1 Y 1 C LYS 744 ? C LYS 744 
447 1 Y 1 C ASN 745 ? C ASN 745 
448 1 Y 1 C SER 746 ? C SER 746 
449 1 Y 1 C ALA 747 ? C ALA 747 
450 1 Y 1 C SER 748 ? C SER 748 
451 1 Y 1 C GLU 749 ? C GLU 749 
452 1 Y 1 C GLU 750 ? C GLU 750 
453 1 Y 1 C ASP 751 ? C ASP 751 
454 1 Y 1 C HIS 752 ? C HIS 752 
455 1 Y 1 C LEU 753 ? C LEU 753 
456 1 Y 1 C PRO 754 ? C PRO 754 
457 1 Y 1 C LEU 755 ? C LEU 755 
458 1 Y 1 C GLN 756 ? C GLN 756 
459 1 Y 1 C VAL 757 ? C VAL 757 
460 1 Y 1 C LEU 758 ? C LEU 758 
461 1 Y 1 C GLN 759 ? C GLN 759 
462 1 Y 1 C SER 760 ? C SER 760 
463 1 Y 1 C PRO 761 ? C PRO 761 
464 1 Y 1 D MET 1   ? D MET 1   
465 1 Y 1 D THR 2   ? D THR 2   
466 1 Y 1 D SER 3   ? D SER 3   
467 1 Y 1 D ALA 4   ? D ALA 4   
468 1 Y 1 D SER 5   ? D SER 5   
469 1 Y 1 D SER 6   ? D SER 6   
470 1 Y 1 D PRO 7   ? D PRO 7   
471 1 Y 1 D PRO 8   ? D PRO 8   
472 1 Y 1 D ALA 9   ? D ALA 9   
473 1 Y 1 D PHE 10  ? D PHE 10  
474 1 Y 1 D ARG 11  ? D ARG 11  
475 1 Y 1 D LEU 12  ? D LEU 12  
476 1 Y 1 D GLU 13  ? D GLU 13  
477 1 Y 1 D THR 14  ? D THR 14  
478 1 Y 1 D SER 15  ? D SER 15  
479 1 Y 1 D ASP 16  ? D ASP 16  
480 1 Y 1 D GLY 17  ? D GLY 17  
481 1 Y 1 D ASP 18  ? D ASP 18  
482 1 Y 1 D GLU 19  ? D GLU 19  
483 1 Y 1 D GLU 20  ? D GLU 20  
484 1 Y 1 D GLY 21  ? D GLY 21  
485 1 Y 1 D ASN 22  ? D ASN 22  
486 1 Y 1 D ALA 23  ? D ALA 23  
487 1 Y 1 D GLU 24  ? D GLU 24  
488 1 Y 1 D VAL 25  ? D VAL 25  
489 1 Y 1 D ASN 26  ? D ASN 26  
490 1 Y 1 D LYS 27  ? D LYS 27  
491 1 Y 1 D GLY 28  ? D GLY 28  
492 1 Y 1 D LYS 29  ? D LYS 29  
493 1 Y 1 D GLN 30  ? D GLN 30  
494 1 Y 1 D GLU 31  ? D GLU 31  
495 1 Y 1 D PRO 32  ? D PRO 32  
496 1 Y 1 D PRO 33  ? D PRO 33  
497 1 Y 1 D PRO 34  ? D PRO 34  
498 1 Y 1 D MET 35  ? D MET 35  
499 1 Y 1 D GLU 36  ? D GLU 36  
500 1 Y 1 D SER 37  ? D SER 37  
501 1 Y 1 D PRO 38  ? D PRO 38  
502 1 Y 1 D PHE 39  ? D PHE 39  
503 1 Y 1 D GLN 40  ? D GLN 40  
504 1 Y 1 D ARG 41  ? D ARG 41  
505 1 Y 1 D GLU 42  ? D GLU 42  
506 1 Y 1 D ASP 43  ? D ASP 43  
507 1 Y 1 D ARG 44  ? D ARG 44  
508 1 Y 1 D ASN 45  ? D ASN 45  
509 1 Y 1 D SER 46  ? D SER 46  
510 1 Y 1 D SER 47  ? D SER 47  
511 1 Y 1 D PRO 48  ? D PRO 48  
512 1 Y 1 D GLN 49  ? D GLN 49  
513 1 Y 1 D ILE 50  ? D ILE 50  
514 1 Y 1 D LYS 51  ? D LYS 51  
515 1 Y 1 D VAL 52  ? D VAL 52  
516 1 Y 1 D ASN 53  ? D ASN 53  
517 1 Y 1 D LEU 54  ? D LEU 54  
518 1 Y 1 D ASN 55  ? D ASN 55  
519 1 Y 1 D PHE 56  ? D PHE 56  
520 1 Y 1 D ILE 57  ? D ILE 57  
521 1 Y 1 D LYS 58  ? D LYS 58  
522 1 Y 1 D ARG 59  ? D ARG 59  
523 1 Y 1 D PRO 60  ? D PRO 60  
524 1 Y 1 D PRO 61  ? D PRO 61  
525 1 Y 1 D LYS 62  ? D LYS 62  
526 1 Y 1 D ASN 63  ? D ASN 63  
527 1 Y 1 D THR 64  ? D THR 64  
528 1 Y 1 D SER 65  ? D SER 65  
529 1 Y 1 D ALA 66  ? D ALA 66  
530 1 Y 1 D PRO 67  ? D PRO 67  
531 1 Y 1 D SER 68  ? D SER 68  
532 1 Y 1 D GLN 69  ? D GLN 69  
533 1 Y 1 D GLN 70  ? D GLN 70  
534 1 Y 1 D GLU 71  ? D GLU 71  
535 1 Y 1 D PRO 72  ? D PRO 72  
536 1 Y 1 D ASP 73  ? D ASP 73  
537 1 Y 1 D ASP 418 ? D ASP 418 
538 1 Y 1 D GLN 419 ? D GLN 419 
539 1 Y 1 D PRO 420 ? D PRO 420 
540 1 Y 1 D ALA 421 ? D ALA 421 
541 1 Y 1 D ILE 422 ? D ILE 422 
542 1 Y 1 D PRO 423 ? D PRO 423 
543 1 Y 1 D SER 424 ? D SER 424 
544 1 Y 1 D SER 425 ? D SER 425 
545 1 Y 1 D LYS 426 ? D LYS 426 
546 1 Y 1 D ALA 427 ? D ALA 427 
547 1 Y 1 D THR 428 ? D THR 428 
548 1 Y 1 D SER 564 ? D SER 564 
549 1 Y 1 D PRO 565 ? D PRO 565 
550 1 Y 1 D LYS 566 ? D LYS 566 
551 1 Y 1 D ALA 567 ? D ALA 567 
552 1 Y 1 D PRO 568 ? D PRO 568 
553 1 Y 1 D GLU 569 ? D GLU 569 
554 1 Y 1 D ASP 570 ? D ASP 570 
555 1 Y 1 D ASN 571 ? D ASN 571 
556 1 Y 1 D ASN 572 ? D ASN 572 
557 1 Y 1 D SER 573 ? D SER 573 
558 1 Y 1 D THR 574 ? D THR 574 
559 1 Y 1 D VAL 575 ? D VAL 575 
560 1 Y 1 D THR 576 ? D THR 576 
561 1 Y 1 D GLU 577 ? D GLU 577 
562 1 Y 1 D GLN 578 ? D GLN 578 
563 1 Y 1 D PRO 579 ? D PRO 579 
564 1 Y 1 D THR 580 ? D THR 580 
565 1 Y 1 D VAL 581 ? D VAL 581 
566 1 Y 1 D GLY 582 ? D GLY 582 
567 1 Y 1 D GLN 583 ? D GLN 583 
568 1 Y 1 D GLU 584 ? D GLU 584 
569 1 Y 1 D GLU 585 ? D GLU 585 
570 1 Y 1 D GLU 586 ? D GLU 586 
571 1 Y 1 D PRO 587 ? D PRO 587 
572 1 Y 1 D ALA 588 ? D ALA 588 
573 1 Y 1 D ASP 696 ? D ASP 696 
574 1 Y 1 D GLY 697 ? D GLY 697 
575 1 Y 1 D THR 698 ? D THR 698 
576 1 Y 1 D PRO 720 ? D PRO 720 
577 1 Y 1 D THR 721 ? D THR 721 
578 1 Y 1 D LEU 722 ? D LEU 722 
579 1 Y 1 D SER 723 ? D SER 723 
580 1 Y 1 D GLU 724 ? D GLU 724 
581 1 Y 1 D ASP 725 ? D ASP 725 
582 1 Y 1 D PRO 726 ? D PRO 726 
583 1 Y 1 D SER 727 ? D SER 727 
584 1 Y 1 D GLY 728 ? D GLY 728 
585 1 Y 1 D PRO 729 ? D PRO 729 
586 1 Y 1 D GLY 730 ? D GLY 730 
587 1 Y 1 D ILE 731 ? D ILE 731 
588 1 Y 1 D THR 732 ? D THR 732 
589 1 Y 1 D GLY 733 ? D GLY 733 
590 1 Y 1 D ASN 734 ? D ASN 734 
591 1 Y 1 D LYS 735 ? D LYS 735 
592 1 Y 1 D LYS 736 ? D LYS 736 
593 1 Y 1 D ASN 737 ? D ASN 737 
594 1 Y 1 D PRO 738 ? D PRO 738 
595 1 Y 1 D THR 739 ? D THR 739 
596 1 Y 1 D SER 740 ? D SER 740 
597 1 Y 1 D LYS 741 ? D LYS 741 
598 1 Y 1 D PRO 742 ? D PRO 742 
599 1 Y 1 D GLY 743 ? D GLY 743 
600 1 Y 1 D LYS 744 ? D LYS 744 
601 1 Y 1 D ASN 745 ? D ASN 745 
602 1 Y 1 D SER 746 ? D SER 746 
603 1 Y 1 D ALA 747 ? D ALA 747 
604 1 Y 1 D SER 748 ? D SER 748 
605 1 Y 1 D GLU 749 ? D GLU 749 
606 1 Y 1 D GLU 750 ? D GLU 750 
607 1 Y 1 D ASP 751 ? D ASP 751 
608 1 Y 1 D HIS 752 ? D HIS 752 
609 1 Y 1 D LEU 753 ? D LEU 753 
610 1 Y 1 D PRO 754 ? D PRO 754 
611 1 Y 1 D LEU 755 ? D LEU 755 
612 1 Y 1 D GLN 756 ? D GLN 756 
613 1 Y 1 D VAL 757 ? D VAL 757 
614 1 Y 1 D LEU 758 ? D LEU 758 
615 1 Y 1 D GLN 759 ? D GLN 759 
616 1 Y 1 D SER 760 ? D SER 760 
617 1 Y 1 D PRO 761 ? D PRO 761 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PEX O1   O N N 247 
PEX O2   O N N 248 
PEX P1   P N N 249 
PEX O3   O N N 250 
PEX C1   C N N 251 
PEX C2   C N R 252 
PEX C3   C N N 253 
PEX O4   O N N 254 
PEX C4   C N N 255 
PEX O5   O N N 256 
PEX C5   C N N 257 
PEX C6   C N N 258 
PEX C7   C N N 259 
PEX C8   C N N 260 
PEX C9   C N N 261 
PEX C10  C N N 262 
PEX C11  C N N 263 
PEX C12  C N N 264 
PEX C13  C N N 265 
PEX O6   O N N 266 
PEX C14  C N N 267 
PEX O7   O N N 268 
PEX C15  C N N 269 
PEX C16  C N N 270 
PEX C17  C N N 271 
PEX C18  C N N 272 
PEX C19  C N N 273 
PEX C20  C N N 274 
PEX C21  C N N 275 
PEX C22  C N N 276 
PEX C23  C N N 277 
PEX O8   O N N 278 
PEX C24  C N N 279 
PEX C25  C N N 280 
PEX N1   N N N 281 
PEX H1   H N N 282 
PEX H2   H N N 283 
PEX H3   H N N 284 
PEX H4   H N N 285 
PEX H5   H N N 286 
PEX H6   H N N 287 
PEX H7   H N N 288 
PEX H8   H N N 289 
PEX H9   H N N 290 
PEX H10  H N N 291 
PEX H11  H N N 292 
PEX H12  H N N 293 
PEX H13  H N N 294 
PEX H14  H N N 295 
PEX H15  H N N 296 
PEX H16  H N N 297 
PEX H17  H N N 298 
PEX H18  H N N 299 
PEX H19  H N N 300 
PEX H20  H N N 301 
PEX H21  H N N 302 
PEX H22  H N N 303 
PEX H23  H N N 304 
PEX H24  H N N 305 
PEX H25  H N N 306 
PEX H26  H N N 307 
PEX H27  H N N 308 
PEX H28  H N N 309 
PEX H29  H N N 310 
PEX H30  H N N 311 
PEX H31  H N N 312 
PEX H32  H N N 313 
PEX H33  H N N 314 
PEX H34  H N N 315 
PEX H35  H N N 316 
PEX H36  H N N 317 
PEX H37  H N N 318 
PEX H38  H N N 319 
PEX H39  H N N 320 
PEX H40  H N N 321 
PEX H41  H N N 322 
PEX H42  H N N 323 
PEX H43  H N N 324 
PEX H44  H N N 325 
PEX H45  H N N 326 
PEX H46  H N N 327 
PEX H47  H N N 328 
PEX H48  H N N 329 
PEX H49  H N N 330 
PHE N    N N N 331 
PHE CA   C N S 332 
PHE C    C N N 333 
PHE O    O N N 334 
PHE CB   C N N 335 
PHE CG   C Y N 336 
PHE CD1  C Y N 337 
PHE CD2  C Y N 338 
PHE CE1  C Y N 339 
PHE CE2  C Y N 340 
PHE CZ   C Y N 341 
PHE OXT  O N N 342 
PHE H    H N N 343 
PHE H2   H N N 344 
PHE HA   H N N 345 
PHE HB2  H N N 346 
PHE HB3  H N N 347 
PHE HD1  H N N 348 
PHE HD2  H N N 349 
PHE HE1  H N N 350 
PHE HE2  H N N 351 
PHE HZ   H N N 352 
PHE HXT  H N N 353 
PRO N    N N N 354 
PRO CA   C N S 355 
PRO C    C N N 356 
PRO O    O N N 357 
PRO CB   C N N 358 
PRO CG   C N N 359 
PRO CD   C N N 360 
PRO OXT  O N N 361 
PRO H    H N N 362 
PRO HA   H N N 363 
PRO HB2  H N N 364 
PRO HB3  H N N 365 
PRO HG2  H N N 366 
PRO HG3  H N N 367 
PRO HD2  H N N 368 
PRO HD3  H N N 369 
PRO HXT  H N N 370 
RTO C13  C Y N 371 
RTO C15  C Y N 372 
RTO C17  C N N 373 
RTO C01  C N N 374 
RTO C02  C N N 375 
RTO C03  C N N 376 
RTO C05  C N N 377 
RTO C06  C N N 378 
RTO C07  C N N 379 
RTO C11  C Y N 380 
RTO C12  C Y N 381 
RTO C14  C Y N 382 
RTO C16  C Y N 383 
RTO N04  N N N 384 
RTO O09  O N N 385 
RTO O10  O N N 386 
RTO O18  O N N 387 
RTO O19  O N N 388 
RTO S08  S N N 389 
RTO H1   H N N 390 
RTO H2   H N N 391 
RTO H3   H N N 392 
RTO H4   H N N 393 
RTO H5   H N N 394 
RTO H6   H N N 395 
RTO H7   H N N 396 
RTO H8   H N N 397 
RTO H9   H N N 398 
RTO H10  H N N 399 
RTO H11  H N N 400 
RTO H12  H N N 401 
RTO H13  H N N 402 
RTO H14  H N N 403 
RTO H15  H N N 404 
RTO H16  H N N 405 
RTO H17  H N N 406 
RTO H18  H N N 407 
RTO H19  H N N 408 
SER N    N N N 409 
SER CA   C N S 410 
SER C    C N N 411 
SER O    O N N 412 
SER CB   C N N 413 
SER OG   O N N 414 
SER OXT  O N N 415 
SER H    H N N 416 
SER H2   H N N 417 
SER HA   H N N 418 
SER HB2  H N N 419 
SER HB3  H N N 420 
SER HG   H N N 421 
SER HXT  H N N 422 
THR N    N N N 423 
THR CA   C N S 424 
THR C    C N N 425 
THR O    O N N 426 
THR CB   C N R 427 
THR OG1  O N N 428 
THR CG2  C N N 429 
THR OXT  O N N 430 
THR H    H N N 431 
THR H2   H N N 432 
THR HA   H N N 433 
THR HB   H N N 434 
THR HG1  H N N 435 
THR HG21 H N N 436 
THR HG22 H N N 437 
THR HG23 H N N 438 
THR HXT  H N N 439 
TRP N    N N N 440 
TRP CA   C N S 441 
TRP C    C N N 442 
TRP O    O N N 443 
TRP CB   C N N 444 
TRP CG   C Y N 445 
TRP CD1  C Y N 446 
TRP CD2  C Y N 447 
TRP NE1  N Y N 448 
TRP CE2  C Y N 449 
TRP CE3  C Y N 450 
TRP CZ2  C Y N 451 
TRP CZ3  C Y N 452 
TRP CH2  C Y N 453 
TRP OXT  O N N 454 
TRP H    H N N 455 
TRP H2   H N N 456 
TRP HA   H N N 457 
TRP HB2  H N N 458 
TRP HB3  H N N 459 
TRP HD1  H N N 460 
TRP HE1  H N N 461 
TRP HE3  H N N 462 
TRP HZ2  H N N 463 
TRP HZ3  H N N 464 
TRP HH2  H N N 465 
TRP HXT  H N N 466 
TYR N    N N N 467 
TYR CA   C N S 468 
TYR C    C N N 469 
TYR O    O N N 470 
TYR CB   C N N 471 
TYR CG   C Y N 472 
TYR CD1  C Y N 473 
TYR CD2  C Y N 474 
TYR CE1  C Y N 475 
TYR CE2  C Y N 476 
TYR CZ   C Y N 477 
TYR OH   O N N 478 
TYR OXT  O N N 479 
TYR H    H N N 480 
TYR H2   H N N 481 
TYR HA   H N N 482 
TYR HB2  H N N 483 
TYR HB3  H N N 484 
TYR HD1  H N N 485 
TYR HD2  H N N 486 
TYR HE1  H N N 487 
TYR HE2  H N N 488 
TYR HH   H N N 489 
TYR HXT  H N N 490 
VAL N    N N N 491 
VAL CA   C N S 492 
VAL C    C N N 493 
VAL O    O N N 494 
VAL CB   C N N 495 
VAL CG1  C N N 496 
VAL CG2  C N N 497 
VAL OXT  O N N 498 
VAL H    H N N 499 
VAL H2   H N N 500 
VAL HA   H N N 501 
VAL HB   H N N 502 
VAL HG11 H N N 503 
VAL HG12 H N N 504 
VAL HG13 H N N 505 
VAL HG21 H N N 506 
VAL HG22 H N N 507 
VAL HG23 H N N 508 
VAL HXT  H N N 509 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PEX O1  P1   sing N N 235 
PEX O2  P1   doub N N 236 
PEX P1  O3   sing N N 237 
PEX P1  O8   sing N N 238 
PEX O3  C1   sing N N 239 
PEX C1  C2   sing N N 240 
PEX C1  H1   sing N N 241 
PEX C1  H2   sing N N 242 
PEX C2  C3   sing N N 243 
PEX C2  O6   sing N N 244 
PEX C2  H3   sing N N 245 
PEX C3  O4   sing N N 246 
PEX C3  H4   sing N N 247 
PEX C3  H5   sing N N 248 
PEX O4  C4   sing N N 249 
PEX C4  O5   doub N N 250 
PEX C4  C5   sing N N 251 
PEX C5  C6   sing N N 252 
PEX C5  H6   sing N N 253 
PEX C5  H7   sing N N 254 
PEX C6  C7   sing N N 255 
PEX C6  H8   sing N N 256 
PEX C6  H9   sing N N 257 
PEX C7  C8   sing N N 258 
PEX C7  H10  sing N N 259 
PEX C7  H11  sing N N 260 
PEX C8  C9   sing N N 261 
PEX C8  H12  sing N N 262 
PEX C8  H13  sing N N 263 
PEX C9  C10  sing N N 264 
PEX C9  H14  sing N N 265 
PEX C9  H15  sing N N 266 
PEX C10 C11  sing N N 267 
PEX C10 H16  sing N N 268 
PEX C10 H17  sing N N 269 
PEX C11 C12  sing N N 270 
PEX C11 H18  sing N N 271 
PEX C11 H19  sing N N 272 
PEX C12 C13  sing N N 273 
PEX C12 H20  sing N N 274 
PEX C12 H21  sing N N 275 
PEX C13 H22  sing N N 276 
PEX C13 H23  sing N N 277 
PEX C13 H24  sing N N 278 
PEX O6  C14  sing N N 279 
PEX C14 O7   doub N N 280 
PEX C14 C15  sing N N 281 
PEX C15 C16  sing N N 282 
PEX C15 H25  sing N N 283 
PEX C15 H26  sing N N 284 
PEX C16 C17  sing N N 285 
PEX C16 H27  sing N N 286 
PEX C16 H28  sing N N 287 
PEX C17 C18  sing N N 288 
PEX C17 H29  sing N N 289 
PEX C17 H30  sing N N 290 
PEX C18 C19  sing N N 291 
PEX C18 H31  sing N N 292 
PEX C18 H32  sing N N 293 
PEX C19 C20  sing N N 294 
PEX C19 H33  sing N N 295 
PEX C19 H34  sing N N 296 
PEX C20 C21  sing N N 297 
PEX C20 H35  sing N N 298 
PEX C20 H36  sing N N 299 
PEX C21 C22  sing N N 300 
PEX C21 H37  sing N N 301 
PEX C21 H38  sing N N 302 
PEX C22 C23  sing N N 303 
PEX C22 H39  sing N N 304 
PEX C22 H40  sing N N 305 
PEX C23 H41  sing N N 306 
PEX C23 H42  sing N N 307 
PEX C23 H43  sing N N 308 
PEX O8  C24  sing N N 309 
PEX C24 C25  sing N N 310 
PEX C24 H44  sing N N 311 
PEX C24 H45  sing N N 312 
PEX C25 N1   sing N N 313 
PEX C25 H46  sing N N 314 
PEX C25 H47  sing N N 315 
PEX N1  H48  sing N N 316 
PEX N1  H49  sing N N 317 
PHE N   CA   sing N N 318 
PHE N   H    sing N N 319 
PHE N   H2   sing N N 320 
PHE CA  C    sing N N 321 
PHE CA  CB   sing N N 322 
PHE CA  HA   sing N N 323 
PHE C   O    doub N N 324 
PHE C   OXT  sing N N 325 
PHE CB  CG   sing N N 326 
PHE CB  HB2  sing N N 327 
PHE CB  HB3  sing N N 328 
PHE CG  CD1  doub Y N 329 
PHE CG  CD2  sing Y N 330 
PHE CD1 CE1  sing Y N 331 
PHE CD1 HD1  sing N N 332 
PHE CD2 CE2  doub Y N 333 
PHE CD2 HD2  sing N N 334 
PHE CE1 CZ   doub Y N 335 
PHE CE1 HE1  sing N N 336 
PHE CE2 CZ   sing Y N 337 
PHE CE2 HE2  sing N N 338 
PHE CZ  HZ   sing N N 339 
PHE OXT HXT  sing N N 340 
PRO N   CA   sing N N 341 
PRO N   CD   sing N N 342 
PRO N   H    sing N N 343 
PRO CA  C    sing N N 344 
PRO CA  CB   sing N N 345 
PRO CA  HA   sing N N 346 
PRO C   O    doub N N 347 
PRO C   OXT  sing N N 348 
PRO CB  CG   sing N N 349 
PRO CB  HB2  sing N N 350 
PRO CB  HB3  sing N N 351 
PRO CG  CD   sing N N 352 
PRO CG  HG2  sing N N 353 
PRO CG  HG3  sing N N 354 
PRO CD  HD2  sing N N 355 
PRO CD  HD3  sing N N 356 
PRO OXT HXT  sing N N 357 
RTO C07 C06  sing N N 358 
RTO C06 C05  sing N N 359 
RTO O10 S08  doub N N 360 
RTO C12 C13  doub Y N 361 
RTO C12 C11  sing Y N 362 
RTO C13 C14  sing Y N 363 
RTO O19 C17  doub N N 364 
RTO S08 C11  sing N N 365 
RTO S08 N04  sing N N 366 
RTO S08 O09  doub N N 367 
RTO C05 N04  sing N N 368 
RTO C11 C16  doub Y N 369 
RTO N04 C03  sing N N 370 
RTO C14 C17  sing N N 371 
RTO C14 C15  doub Y N 372 
RTO C17 O18  sing N N 373 
RTO C03 C02  sing N N 374 
RTO C16 C15  sing Y N 375 
RTO C02 C01  sing N N 376 
RTO C13 H1   sing N N 377 
RTO C15 H2   sing N N 378 
RTO C01 H3   sing N N 379 
RTO C01 H4   sing N N 380 
RTO C01 H5   sing N N 381 
RTO C02 H6   sing N N 382 
RTO C02 H7   sing N N 383 
RTO C03 H8   sing N N 384 
RTO C03 H9   sing N N 385 
RTO C05 H10  sing N N 386 
RTO C05 H11  sing N N 387 
RTO C06 H12  sing N N 388 
RTO C06 H13  sing N N 389 
RTO C07 H14  sing N N 390 
RTO C07 H15  sing N N 391 
RTO C07 H16  sing N N 392 
RTO C12 H17  sing N N 393 
RTO C16 H18  sing N N 394 
RTO O18 H19  sing N N 395 
SER N   CA   sing N N 396 
SER N   H    sing N N 397 
SER N   H2   sing N N 398 
SER CA  C    sing N N 399 
SER CA  CB   sing N N 400 
SER CA  HA   sing N N 401 
SER C   O    doub N N 402 
SER C   OXT  sing N N 403 
SER CB  OG   sing N N 404 
SER CB  HB2  sing N N 405 
SER CB  HB3  sing N N 406 
SER OG  HG   sing N N 407 
SER OXT HXT  sing N N 408 
THR N   CA   sing N N 409 
THR N   H    sing N N 410 
THR N   H2   sing N N 411 
THR CA  C    sing N N 412 
THR CA  CB   sing N N 413 
THR CA  HA   sing N N 414 
THR C   O    doub N N 415 
THR C   OXT  sing N N 416 
THR CB  OG1  sing N N 417 
THR CB  CG2  sing N N 418 
THR CB  HB   sing N N 419 
THR OG1 HG1  sing N N 420 
THR CG2 HG21 sing N N 421 
THR CG2 HG22 sing N N 422 
THR CG2 HG23 sing N N 423 
THR OXT HXT  sing N N 424 
TRP N   CA   sing N N 425 
TRP N   H    sing N N 426 
TRP N   H2   sing N N 427 
TRP CA  C    sing N N 428 
TRP CA  CB   sing N N 429 
TRP CA  HA   sing N N 430 
TRP C   O    doub N N 431 
TRP C   OXT  sing N N 432 
TRP CB  CG   sing N N 433 
TRP CB  HB2  sing N N 434 
TRP CB  HB3  sing N N 435 
TRP CG  CD1  doub Y N 436 
TRP CG  CD2  sing Y N 437 
TRP CD1 NE1  sing Y N 438 
TRP CD1 HD1  sing N N 439 
TRP CD2 CE2  doub Y N 440 
TRP CD2 CE3  sing Y N 441 
TRP NE1 CE2  sing Y N 442 
TRP NE1 HE1  sing N N 443 
TRP CE2 CZ2  sing Y N 444 
TRP CE3 CZ3  doub Y N 445 
TRP CE3 HE3  sing N N 446 
TRP CZ2 CH2  doub Y N 447 
TRP CZ2 HZ2  sing N N 448 
TRP CZ3 CH2  sing Y N 449 
TRP CZ3 HZ3  sing N N 450 
TRP CH2 HH2  sing N N 451 
TRP OXT HXT  sing N N 452 
TYR N   CA   sing N N 453 
TYR N   H    sing N N 454 
TYR N   H2   sing N N 455 
TYR CA  C    sing N N 456 
TYR CA  CB   sing N N 457 
TYR CA  HA   sing N N 458 
TYR C   O    doub N N 459 
TYR C   OXT  sing N N 460 
TYR CB  CG   sing N N 461 
TYR CB  HB2  sing N N 462 
TYR CB  HB3  sing N N 463 
TYR CG  CD1  doub Y N 464 
TYR CG  CD2  sing Y N 465 
TYR CD1 CE1  sing Y N 466 
TYR CD1 HD1  sing N N 467 
TYR CD2 CE2  doub Y N 468 
TYR CD2 HD2  sing N N 469 
TYR CE1 CZ   doub Y N 470 
TYR CE1 HE1  sing N N 471 
TYR CE2 CZ   sing Y N 472 
TYR CE2 HE2  sing N N 473 
TYR CZ  OH   sing N N 474 
TYR OH  HH   sing N N 475 
TYR OXT HXT  sing N N 476 
VAL N   CA   sing N N 477 
VAL N   H    sing N N 478 
VAL N   H2   sing N N 479 
VAL CA  C    sing N N 480 
VAL CA  CB   sing N N 481 
VAL CA  HA   sing N N 482 
VAL C   O    doub N N 483 
VAL C   OXT  sing N N 484 
VAL CB  CG1  sing N N 485 
VAL CB  CG2  sing N N 486 
VAL CB  HB   sing N N 487 
VAL CG1 HG11 sing N N 488 
VAL CG1 HG12 sing N N 489 
VAL CG1 HG13 sing N N 490 
VAL CG2 HG21 sing N N 491 
VAL CG2 HG22 sing N N 492 
VAL CG2 HG23 sing N N 493 
VAL OXT HXT  sing N N 494 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-03-20 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9B3U 
_em_admin.last_update        2025-03-05 
_em_admin.map_release_date   2025-02-26 
_em_admin.title              'Rat TRPV2 WT bound to probenecid' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          10116 
_em_entity_assembly_naturalsource.organism             'Rattus norvegicus' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          4932 
_em_entity_assembly_recombinant.organism             'Saccharomyces cerevisiae' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         42 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ? ? 
MASKING                    ? 3  ? ? ? ? ? 
'CTF CORRECTION'           ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ? ? 
'MODEL FITTING'            ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'         ? 8  ? ? ? ? ? 
OTHER                      ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ? ? 
CLASSIFICATION             ? 12 1 ? ? ? ? 
RECONSTRUCTION             ? 13 1 ? ? ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           R35GM144120 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9B3U 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . ARG A 1 74  ? 174.645 80.327  88.724  1.00 118.61 ? 74  ARG A N   1 
ATOM   2     C CA  . ARG A 1 74  ? 173.577 80.211  89.755  1.00 119.70 ? 74  ARG A CA  1 
ATOM   3     C C   . ARG A 1 74  ? 172.712 81.472  89.758  1.00 119.77 ? 74  ARG A C   1 
ATOM   4     O O   . ARG A 1 74  ? 172.919 82.334  88.878  1.00 119.17 ? 74  ARG A O   1 
ATOM   5     N N   . PHE A 1 75  ? 171.796 81.573  90.725  1.00 116.99 ? 75  PHE A N   1 
ATOM   6     C CA  . PHE A 1 75  ? 170.902 82.738  90.828  1.00 116.91 ? 75  PHE A CA  1 
ATOM   7     C C   . PHE A 1 75  ? 170.421 82.890  92.281  1.00 116.45 ? 75  PHE A C   1 
ATOM   8     O O   . PHE A 1 75  ? 169.988 81.922  92.899  1.00 115.50 ? 75  PHE A O   1 
ATOM   9     C CB  . PHE A 1 75  ? 169.729 82.600  89.846  1.00 116.08 ? 75  PHE A CB  1 
ATOM   10    C CG  . PHE A 1 75  ? 169.202 83.923  89.317  1.00 115.97 ? 75  PHE A CG  1 
ATOM   11    C CD1 . PHE A 1 75  ? 168.645 84.889  90.176  1.00 115.54 ? 75  PHE A CD1 1 
ATOM   12    C CD2 . PHE A 1 75  ? 169.259 84.182  87.936  1.00 115.49 ? 75  PHE A CD2 1 
ATOM   13    C CE1 . PHE A 1 75  ? 168.139 86.092  89.659  1.00 115.90 ? 75  PHE A CE1 1 
ATOM   14    C CE2 . PHE A 1 75  ? 168.725 85.370  87.417  1.00 115.28 ? 75  PHE A CE2 1 
ATOM   15    C CZ  . PHE A 1 75  ? 168.163 86.329  88.278  1.00 115.32 ? 75  PHE A CZ  1 
ATOM   16    N N   . ASP A 1 76  ? 170.502 84.090  92.850  1.00 114.73 ? 76  ASP A N   1 
ATOM   17    C CA  . ASP A 1 76  ? 170.442 84.283  94.304  1.00 114.26 ? 76  ASP A CA  1 
ATOM   18    C C   . ASP A 1 76  ? 169.618 85.520  94.705  1.00 115.33 ? 76  ASP A C   1 
ATOM   19    O O   . ASP A 1 76  ? 169.373 86.413  93.895  1.00 114.72 ? 76  ASP A O   1 
ATOM   20    C CB  . ASP A 1 76  ? 171.886 84.333  94.836  1.00 113.94 ? 76  ASP A CB  1 
ATOM   21    C CG  . ASP A 1 76  ? 172.040 83.778  96.255  1.00 115.37 ? 76  ASP A CG  1 
ATOM   22    O OD1 . ASP A 1 76  ? 171.036 83.709  96.997  1.00 115.09 ? 76  ASP A OD1 1 
ATOM   23    O OD2 . ASP A 1 76  ? 173.177 83.395  96.606  1.00 115.34 ? 76  ASP A OD2 1 
ATOM   24    N N   . ARG A 1 77  ? 169.174 85.557  95.967  1.00 109.43 ? 77  ARG A N   1 
ATOM   25    C CA  . ARG A 1 77  ? 168.185 86.511  96.498  1.00 107.82 ? 77  ARG A CA  1 
ATOM   26    C C   . ARG A 1 77  ? 168.559 87.974  96.272  1.00 107.81 ? 77  ARG A C   1 
ATOM   27    O O   . ARG A 1 77  ? 167.736 88.742  95.784  1.00 108.19 ? 77  ARG A O   1 
ATOM   28    C CB  . ARG A 1 77  ? 167.951 86.194  97.986  1.00 107.25 ? 77  ARG A CB  1 
ATOM   29    C CG  . ARG A 1 77  ? 167.209 87.308  98.734  1.00 107.65 ? 77  ARG A CG  1 
ATOM   30    C CD  . ARG A 1 77  ? 166.581 86.857  100.054 1.00 107.52 ? 77  ARG A CD  1 
ATOM   31    N NE  . ARG A 1 77  ? 167.487 86.064  100.902 1.00 108.01 ? 77  ARG A NE  1 
ATOM   32    C CZ  . ARG A 1 77  ? 168.105 86.443  102.004 1.00 108.37 ? 77  ARG A CZ  1 
ATOM   33    N NH1 . ARG A 1 77  ? 168.729 85.566  102.729 1.00 108.42 ? 77  ARG A NH1 1 
ATOM   34    N NH2 . ARG A 1 77  ? 168.136 87.679  102.401 1.00 107.36 ? 77  ARG A NH2 1 
ATOM   35    N N   . ASP A 1 78  ? 169.790 88.362  96.590  1.00 109.09 ? 78  ASP A N   1 
ATOM   36    C CA  . ASP A 1 78  ? 170.236 89.757  96.489  1.00 109.11 ? 78  ASP A CA  1 
ATOM   37    C C   . ASP A 1 78  ? 170.308 90.262  95.036  1.00 108.60 ? 78  ASP A C   1 
ATOM   38    O O   . ASP A 1 78  ? 170.066 91.439  94.781  1.00 107.75 ? 78  ASP A O   1 
ATOM   39    C CB  . ASP A 1 78  ? 171.582 89.921  97.208  1.00 109.08 ? 78  ASP A CB  1 
ATOM   40    C CG  . ASP A 1 78  ? 171.523 89.547  98.696  1.00 108.73 ? 78  ASP A CG  1 
ATOM   41    O OD1 . ASP A 1 78  ? 170.467 89.730  99.334  1.00 108.59 ? 78  ASP A OD1 1 
ATOM   42    O OD2 . ASP A 1 78  ? 172.549 89.079  99.231  1.00 108.76 ? 78  ASP A OD2 1 
ATOM   43    N N   . ARG A 1 79  ? 170.571 89.370  94.069  1.00 111.67 ? 79  ARG A N   1 
ATOM   44    C CA  . ARG A 1 79  ? 170.405 89.657  92.634  1.00 113.14 ? 79  ARG A CA  1 
ATOM   45    C C   . ARG A 1 79  ? 168.925 89.780  92.304  1.00 113.16 ? 79  ARG A C   1 
ATOM   46    O O   . ARG A 1 79  ? 168.490 90.813  91.796  1.00 112.36 ? 79  ARG A O   1 
ATOM   47    C CB  . ARG A 1 79  ? 171.108 88.572  91.790  1.00 113.00 ? 79  ARG A CB  1 
ATOM   48    C CG  . ARG A 1 79  ? 170.888 88.719  90.277  1.00 112.19 ? 79  ARG A CG  1 
ATOM   49    C CD  . ARG A 1 79  ? 171.611 87.608  89.502  1.00 111.84 ? 79  ARG A CD  1 
ATOM   50    N NE  . ARG A 1 79  ? 171.155 87.538  88.099  1.00 113.72 ? 79  ARG A NE  1 
ATOM   51    C CZ  . ARG A 1 79  ? 171.883 87.607  87.002  1.00 113.09 ? 79  ARG A CZ  1 
ATOM   52    N NH1 . ARG A 1 79  ? 171.322 87.536  85.833  1.00 112.24 ? 79  ARG A NH1 1 
ATOM   53    N NH2 . ARG A 1 79  ? 173.174 87.735  87.034  1.00 112.29 ? 79  ARG A NH2 1 
ATOM   54    N N   . LEU A 1 80  ? 168.124 88.764  92.637  1.00 109.89 ? 80  LEU A N   1 
ATOM   55    C CA  . LEU A 1 80  ? 166.697 88.681  92.306  1.00 108.95 ? 80  LEU A CA  1 
ATOM   56    C C   . LEU A 1 80  ? 165.888 89.885  92.806  1.00 108.06 ? 80  LEU A C   1 
ATOM   57    O O   . LEU A 1 80  ? 165.177 90.521  92.032  1.00 108.57 ? 80  LEU A O   1 
ATOM   58    C CB  . LEU A 1 80  ? 166.151 87.355  92.872  1.00 108.09 ? 80  LEU A CB  1 
ATOM   59    C CG  . LEU A 1 80  ? 164.653 87.135  92.624  1.00 108.19 ? 80  LEU A CG  1 
ATOM   60    C CD1 . LEU A 1 80  ? 164.312 87.145  91.139  1.00 108.96 ? 80  LEU A CD1 1 
ATOM   61    C CD2 . LEU A 1 80  ? 164.241 85.792  93.208  1.00 107.98 ? 80  LEU A CD2 1 
ATOM   62    N N   . PHE A 1 81  ? 166.031 90.246  94.080  1.00 101.81 ? 81  PHE A N   1 
ATOM   63    C CA  . PHE A 1 81  ? 165.376 91.419  94.671  1.00 101.83 ? 81  PHE A CA  1 
ATOM   64    C C   . PHE A 1 81  ? 165.773 92.739  93.991  1.00 103.63 ? 81  PHE A C   1 
ATOM   65    O O   . PHE A 1 81  ? 165.008 93.704  94.024  1.00 102.72 ? 81  PHE A O   1 
ATOM   66    C CB  . PHE A 1 81  ? 165.723 91.483  96.160  1.00 100.91 ? 81  PHE A CB  1 
ATOM   67    C CG  . PHE A 1 81  ? 165.071 90.459  97.071  1.00 102.04 ? 81  PHE A CG  1 
ATOM   68    C CD1 . PHE A 1 81  ? 164.148 89.495  96.610  1.00 101.54 ? 81  PHE A CD1 1 
ATOM   69    C CD2 . PHE A 1 81  ? 165.372 90.521  98.443  1.00 102.30 ? 81  PHE A CD2 1 
ATOM   70    C CE1 . PHE A 1 81  ? 163.526 88.625  97.520  1.00 101.23 ? 81  PHE A CE1 1 
ATOM   71    C CE2 . PHE A 1 81  ? 164.744 89.652  99.349  1.00 101.18 ? 81  PHE A CE2 1 
ATOM   72    C CZ  . PHE A 1 81  ? 163.810 88.713  98.890  1.00 101.26 ? 81  PHE A CZ  1 
ATOM   73    N N   . SER A 1 82  ? 166.941 92.797  93.350  1.00 107.93 ? 82  SER A N   1 
ATOM   74    C CA  . SER A 1 82  ? 167.346 93.965  92.564  1.00 107.33 ? 82  SER A CA  1 
ATOM   75    C C   . SER A 1 82  ? 166.672 93.973  91.185  1.00 106.80 ? 82  SER A C   1 
ATOM   76    O O   . SER A 1 82  ? 166.178 95.011  90.747  1.00 106.41 ? 82  SER A O   1 
ATOM   77    C CB  . SER A 1 82  ? 168.875 93.991  92.451  1.00 107.69 ? 82  SER A CB  1 
ATOM   78    O OG  . SER A 1 82  ? 169.341 95.245  91.992  1.00 107.59 ? 82  SER A OG  1 
ATOM   79    N N   . VAL A 1 83  ? 166.530 92.798  90.557  1.00 105.97 ? 83  VAL A N   1 
ATOM   80    C CA  . VAL A 1 83  ? 165.805 92.628  89.285  1.00 106.99 ? 83  VAL A CA  1 
ATOM   81    C C   . VAL A 1 83  ? 164.316 92.953  89.420  1.00 107.18 ? 83  VAL A C   1 
ATOM   82    O O   . VAL A 1 83  ? 163.793 93.701  88.602  1.00 106.68 ? 83  VAL A O   1 
ATOM   83    C CB  . VAL A 1 83  ? 165.975 91.208  88.710  1.00 107.33 ? 83  VAL A CB  1 
ATOM   84    C CG1 . VAL A 1 83  ? 165.246 91.049  87.370  1.00 107.66 ? 83  VAL A CG1 1 
ATOM   85    C CG2 . VAL A 1 83  ? 167.446 90.884  88.467  1.00 107.11 ? 83  VAL A CG2 1 
ATOM   86    N N   . VAL A 1 84  ? 163.619 92.457  90.452  1.00 100.60 ? 84  VAL A N   1 
ATOM   87    C CA  . VAL A 1 84  ? 162.162 92.676  90.579  1.00 99.16  ? 84  VAL A CA  1 
ATOM   88    C C   . VAL A 1 84  ? 161.753 94.143  90.766  1.00 98.71  ? 84  VAL A C   1 
ATOM   89    O O   . VAL A 1 84  ? 160.591 94.476  90.560  1.00 98.07  ? 84  VAL A O   1 
ATOM   90    C CB  . VAL A 1 84  ? 161.508 91.803  91.663  1.00 97.82  ? 84  VAL A CB  1 
ATOM   91    C CG1 . VAL A 1 84  ? 161.802 90.317  91.480  1.00 97.74  ? 84  VAL A CG1 1 
ATOM   92    C CG2 . VAL A 1 84  ? 161.885 92.212  93.083  1.00 97.36  ? 84  VAL A CG2 1 
ATOM   93    N N   . SER A 1 85  ? 162.677 95.036  91.127  1.00 102.32 ? 85  SER A N   1 
ATOM   94    C CA  . SER A 1 85  ? 162.444 96.486  91.187  1.00 102.53 ? 85  SER A CA  1 
ATOM   95    C C   . SER A 1 85  ? 162.741 97.225  89.860  1.00 103.46 ? 85  SER A C   1 
ATOM   96    O O   . SER A 1 85  ? 162.316 98.369  89.681  1.00 102.75 ? 85  SER A O   1 
ATOM   97    C CB  . SER A 1 85  ? 163.258 97.058  92.355  1.00 101.12 ? 85  SER A CB  1 
ATOM   98    O OG  . SER A 1 85  ? 162.961 98.419  92.583  1.00 101.53 ? 85  SER A OG  1 
ATOM   99    N N   . ARG A 1 86  ? 163.385 96.545  88.893  1.00 109.96 ? 86  ARG A N   1 
ATOM   100   C CA  . ARG A 1 86  ? 163.726 97.170  87.572  1.00 111.01 ? 86  ARG A CA  1 
ATOM   101   C C   . ARG A 1 86  ? 162.597 96.986  86.558  1.00 112.11 ? 86  ARG A C   1 
ATOM   102   O O   . ARG A 1 86  ? 161.830 96.013  86.691  1.00 110.05 ? 86  ARG A O   1 
ATOM   103   C CB  . ARG A 1 86  ? 165.045 96.605  87.000  1.00 111.50 ? 86  ARG A CB  1 
ATOM   104   C CG  . ARG A 1 86  ? 166.258 97.340  87.578  1.00 110.38 ? 86  ARG A CG  1 
ATOM   105   C CD  . ARG A 1 86  ? 167.576 96.826  87.029  1.00 110.85 ? 86  ARG A CD  1 
ATOM   106   N NE  . ARG A 1 86  ? 167.873 95.456  87.424  1.00 111.18 ? 86  ARG A NE  1 
ATOM   107   C CZ  . ARG A 1 86  ? 168.522 95.119  88.532  1.00 110.34 ? 86  ARG A CZ  1 
ATOM   108   N NH1 . ARG A 1 86  ? 168.753 93.846  88.803  1.00 110.51 ? 86  ARG A NH1 1 
ATOM   109   N NH2 . ARG A 1 86  ? 168.937 96.054  89.367  1.00 109.54 ? 86  ARG A NH2 1 
ATOM   110   N N   . GLY A 1 87  ? 162.514 97.890  85.587  1.00 117.59 ? 87  GLY A N   1 
ATOM   111   C CA  . GLY A 1 87  ? 161.522 97.872  84.504  1.00 116.19 ? 87  GLY A CA  1 
ATOM   112   C C   . GLY A 1 87  ? 161.792 96.845  83.393  1.00 116.91 ? 87  GLY A C   1 
ATOM   113   O O   . GLY A 1 87  ? 160.910 96.581  82.580  1.00 116.95 ? 87  GLY A O   1 
ATOM   114   N N   . VAL A 1 88  ? 162.988 96.246  83.362  1.00 119.52 ? 88  VAL A N   1 
ATOM   115   C CA  . VAL A 1 88  ? 163.353 95.152  82.444  1.00 120.18 ? 88  VAL A CA  1 
ATOM   116   C C   . VAL A 1 88  ? 163.481 93.817  83.202  1.00 119.70 ? 88  VAL A C   1 
ATOM   117   O O   . VAL A 1 88  ? 164.314 93.705  84.102  1.00 118.63 ? 88  VAL A O   1 
ATOM   118   N N   . PRO A 1 89  ? 162.701 92.779  82.850  1.00 117.63 ? 89  PRO A N   1 
ATOM   119   C CA  . PRO A 1 89  ? 162.760 91.469  83.503  1.00 117.44 ? 89  PRO A CA  1 
ATOM   120   C C   . PRO A 1 89  ? 163.840 90.518  82.951  1.00 118.00 ? 89  PRO A C   1 
ATOM   121   O O   . PRO A 1 89  ? 164.029 89.438  83.500  1.00 117.15 ? 89  PRO A O   1 
ATOM   122   C CB  . PRO A 1 89  ? 161.367 90.882  83.295  1.00 115.87 ? 89  PRO A CB  1 
ATOM   123   C CG  . PRO A 1 89  ? 160.957 91.432  81.932  1.00 115.67 ? 89  PRO A CG  1 
ATOM   124   C CD  . PRO A 1 89  ? 161.565 92.831  81.937  1.00 115.86 ? 89  PRO A CD  1 
ATOM   125   N N   . GLU A 1 90  ? 164.549 90.860  81.870  1.00 117.58 ? 90  GLU A N   1 
ATOM   126   C CA  . GLU A 1 90  ? 165.430 89.905  81.177  1.00 117.59 ? 90  GLU A CA  1 
ATOM   127   C C   . GLU A 1 90  ? 166.579 89.360  82.042  1.00 117.74 ? 90  GLU A C   1 
ATOM   128   O O   . GLU A 1 90  ? 167.069 88.253  81.818  1.00 117.52 ? 90  GLU A O   1 
ATOM   129   N N   . GLU A 1 91  ? 166.990 90.097  83.076  1.00 114.74 ? 91  GLU A N   1 
ATOM   130   C CA  . GLU A 1 91  ? 168.031 89.676  84.024  1.00 115.05 ? 91  GLU A CA  1 
ATOM   131   C C   . GLU A 1 91  ? 167.621 88.444  84.861  1.00 114.93 ? 91  GLU A C   1 
ATOM   132   O O   . GLU A 1 91  ? 168.483 87.803  85.464  1.00 114.87 ? 91  GLU A O   1 
ATOM   133   N N   . LEU A 1 92  ? 166.340 88.039  84.839  1.00 114.17 ? 92  LEU A N   1 
ATOM   134   C CA  . LEU A 1 92  ? 165.856 86.756  85.368  1.00 114.97 ? 92  LEU A CA  1 
ATOM   135   C C   . LEU A 1 92  ? 166.374 85.528  84.592  1.00 114.75 ? 92  LEU A C   1 
ATOM   136   O O   . LEU A 1 92  ? 166.246 84.406  85.078  1.00 114.30 ? 92  LEU A O   1 
ATOM   137   C CB  . LEU A 1 92  ? 164.314 86.717  85.358  1.00 115.20 ? 92  LEU A CB  1 
ATOM   138   C CG  . LEU A 1 92  ? 163.584 87.747  86.235  1.00 115.12 ? 92  LEU A CG  1 
ATOM   139   C CD1 . LEU A 1 92  ? 162.091 87.609  85.989  1.00 113.63 ? 92  LEU A CD1 1 
ATOM   140   C CD2 . LEU A 1 92  ? 163.840 87.552  87.726  1.00 113.56 ? 92  LEU A CD2 1 
ATOM   141   N N   . THR A 1 93  ? 166.927 85.693  83.387  1.00 116.02 ? 93  THR A N   1 
ATOM   142   C CA  . THR A 1 93  ? 167.432 84.560  82.584  1.00 115.27 ? 93  THR A CA  1 
ATOM   143   C C   . THR A 1 93  ? 168.494 83.751  83.341  1.00 116.21 ? 93  THR A C   1 
ATOM   144   O O   . THR A 1 93  ? 169.446 84.302  83.893  1.00 116.61 ? 93  THR A O   1 
ATOM   145   C CB  . THR A 1 93  ? 167.960 85.016  81.216  1.00 114.55 ? 93  THR A CB  1 
ATOM   146   O OG1 . THR A 1 93  ? 168.756 86.176  81.304  1.00 114.62 ? 93  THR A OG1 1 
ATOM   147   C CG2 . THR A 1 93  ? 166.817 85.322  80.257  1.00 114.86 ? 93  THR A CG2 1 
ATOM   148   N N   . GLY A 1 94  ? 168.310 82.429  83.405  1.00 116.70 ? 94  GLY A N   1 
ATOM   149   C CA  . GLY A 1 94  ? 169.098 81.510  84.238  1.00 116.50 ? 94  GLY A CA  1 
ATOM   150   C C   . GLY A 1 94  ? 168.435 81.106  85.565  1.00 117.33 ? 94  GLY A C   1 
ATOM   151   O O   . GLY A 1 94  ? 168.851 80.114  86.170  1.00 117.01 ? 94  GLY A O   1 
ATOM   152   N N   . LEU A 1 95  ? 167.421 81.842  86.046  1.00 117.26 ? 95  LEU A N   1 
ATOM   153   C CA  . LEU A 1 95  ? 166.760 81.578  87.337  1.00 116.27 ? 95  LEU A CA  1 
ATOM   154   C C   . LEU A 1 95  ? 165.993 80.247  87.345  1.00 115.86 ? 95  LEU A C   1 
ATOM   155   O O   . LEU A 1 95  ? 166.174 79.452  88.263  1.00 115.25 ? 95  LEU A O   1 
ATOM   156   C CB  . LEU A 1 95  ? 165.845 82.767  87.686  1.00 115.55 ? 95  LEU A CB  1 
ATOM   157   C CG  . LEU A 1 95  ? 165.023 82.640  88.981  1.00 116.35 ? 95  LEU A CG  1 
ATOM   158   C CD1 . LEU A 1 95  ? 165.879 82.458  90.231  1.00 115.36 ? 95  LEU A CD1 1 
ATOM   159   C CD2 . LEU A 1 95  ? 164.211 83.917  89.158  1.00 115.43 ? 95  LEU A CD2 1 
ATOM   160   N N   . LEU A 1 96  ? 165.183 79.989  86.319  1.00 116.63 ? 96  LEU A N   1 
ATOM   161   C CA  . LEU A 1 96  ? 164.449 78.731  86.199  1.00 117.64 ? 96  LEU A CA  1 
ATOM   162   C C   . LEU A 1 96  ? 165.407 77.531  86.117  1.00 118.75 ? 96  LEU A C   1 
ATOM   163   O O   . LEU A 1 96  ? 165.187 76.527  86.791  1.00 118.59 ? 96  LEU A O   1 
ATOM   164   C CB  . LEU A 1 96  ? 163.517 78.827  84.981  1.00 117.16 ? 96  LEU A CB  1 
ATOM   165   C CG  . LEU A 1 96  ? 162.717 77.547  84.690  1.00 117.58 ? 96  LEU A CG  1 
ATOM   166   C CD1 . LEU A 1 96  ? 161.800 77.152  85.846  1.00 116.49 ? 96  LEU A CD1 1 
ATOM   167   C CD2 . LEU A 1 96  ? 161.871 77.772  83.441  1.00 116.98 ? 96  LEU A CD2 1 
ATOM   168   N N   . GLU A 1 97  ? 166.499 77.640  85.354  1.00 118.70 ? 97  GLU A N   1 
ATOM   169   C CA  . GLU A 1 97  ? 167.538 76.618  85.268  1.00 118.25 ? 97  GLU A CA  1 
ATOM   170   C C   . GLU A 1 97  ? 168.186 76.348  86.634  1.00 118.29 ? 97  GLU A C   1 
ATOM   171   O O   . GLU A 1 97  ? 168.309 75.191  87.037  1.00 117.53 ? 97  GLU A O   1 
ATOM   172   N N   . TYR A 1 98  ? 168.547 77.391  87.385  1.00 119.30 ? 98  TYR A N   1 
ATOM   173   C CA  . TYR A 1 98  ? 169.161 77.226  88.703  1.00 119.54 ? 98  TYR A CA  1 
ATOM   174   C C   . TYR A 1 98  ? 168.190 76.664  89.752  1.00 119.53 ? 98  TYR A C   1 
ATOM   175   O O   . TYR A 1 98  ? 168.543 75.739  90.482  1.00 119.13 ? 98  TYR A O   1 
ATOM   176   C CB  . TYR A 1 98  ? 169.763 78.554  89.166  1.00 118.86 ? 98  TYR A CB  1 
ATOM   177   C CG  . TYR A 1 98  ? 170.540 78.417  90.456  1.00 119.31 ? 98  TYR A CG  1 
ATOM   178   C CD1 . TYR A 1 98  ? 171.727 77.664  90.482  1.00 119.44 ? 98  TYR A CD1 1 
ATOM   179   C CD2 . TYR A 1 98  ? 170.064 79.004  91.641  1.00 119.34 ? 98  TYR A CD2 1 
ATOM   180   C CE1 . TYR A 1 98  ? 172.441 77.503  91.685  1.00 119.27 ? 98  TYR A CE1 1 
ATOM   181   C CE2 . TYR A 1 98  ? 170.782 78.853  92.844  1.00 119.27 ? 98  TYR A CE2 1 
ATOM   182   C CZ  . TYR A 1 98  ? 171.973 78.101  92.868  1.00 119.24 ? 98  TYR A CZ  1 
ATOM   183   O OH  . TYR A 1 98  ? 172.680 77.968  94.019  1.00 119.59 ? 98  TYR A OH  1 
ATOM   184   N N   . LEU A 1 99  ? 166.953 77.165  89.800  1.00 118.21 ? 99  LEU A N   1 
ATOM   185   C CA  . LEU A 1 99  ? 165.902 76.650  90.682  1.00 118.72 ? 99  LEU A CA  1 
ATOM   186   C C   . LEU A 1 99  ? 165.596 75.173  90.395  1.00 118.30 ? 99  LEU A C   1 
ATOM   187   O O   . LEU A 1 99  ? 165.619 74.345  91.306  1.00 117.34 ? 99  LEU A O   1 
ATOM   188   C CB  . LEU A 1 99  ? 164.626 77.490  90.495  1.00 118.65 ? 99  LEU A CB  1 
ATOM   189   C CG  . LEU A 1 99  ? 164.672 78.900  91.106  1.00 118.03 ? 99  LEU A CG  1 
ATOM   190   C CD1 . LEU A 1 99  ? 163.431 79.668  90.653  1.00 116.65 ? 99  LEU A CD1 1 
ATOM   191   C CD2 . LEU A 1 99  ? 164.688 78.887  92.632  1.00 117.05 ? 99  LEU A CD2 1 
ATOM   192   N N   . ARG A 1 100 ? 165.335 74.832  89.129  1.00 119.31 ? 100 ARG A N   1 
ATOM   193   C CA  . ARG A 1 100 ? 164.871 73.494  88.723  1.00 119.54 ? 100 ARG A CA  1 
ATOM   194   C C   . ARG A 1 100 ? 165.992 72.448  88.677  1.00 119.57 ? 100 ARG A C   1 
ATOM   195   O O   . ARG A 1 100 ? 165.721 71.269  88.893  1.00 118.82 ? 100 ARG A O   1 
ATOM   196   C CB  . ARG A 1 100 ? 164.100 73.644  87.398  1.00 119.18 ? 100 ARG A CB  1 
ATOM   197   C CG  . ARG A 1 100 ? 163.190 72.453  87.072  1.00 118.90 ? 100 ARG A CG  1 
ATOM   198   C CD  . ARG A 1 100 ? 162.123 72.826  86.034  1.00 118.50 ? 100 ARG A CD  1 
ATOM   199   N NE  . ARG A 1 100 ? 162.703 73.222  84.742  1.00 119.54 ? 100 ARG A NE  1 
ATOM   200   C CZ  . ARG A 1 100 ? 162.052 73.693  83.695  1.00 119.45 ? 100 ARG A CZ  1 
ATOM   201   N NH1 . ARG A 1 100 ? 162.687 73.948  82.591  1.00 118.72 ? 100 ARG A NH1 1 
ATOM   202   N NH2 . ARG A 1 100 ? 160.773 73.929  83.711  1.00 118.79 ? 100 ARG A NH2 1 
ATOM   203   N N   . TRP A 1 101 ? 167.249 72.855  88.476  1.00 122.09 ? 101 TRP A N   1 
ATOM   204   C CA  . TRP A 1 101 ? 168.415 71.971  88.598  1.00 122.35 ? 101 TRP A CA  1 
ATOM   205   C C   . TRP A 1 101 ? 168.863 71.732  90.049  1.00 122.56 ? 101 TRP A C   1 
ATOM   206   O O   . TRP A 1 101 ? 169.407 70.668  90.350  1.00 122.61 ? 101 TRP A O   1 
ATOM   207   C CB  . TRP A 1 101 ? 169.571 72.559  87.798  1.00 121.13 ? 101 TRP A CB  1 
ATOM   208   N N   . ASN A 1 102 ? 168.630 72.682  90.965  1.00 121.10 ? 102 ASN A N   1 
ATOM   209   C CA  . ASN A 1 102 ? 168.971 72.554  92.389  1.00 120.92 ? 102 ASN A CA  1 
ATOM   210   C C   . ASN A 1 102 ? 167.768 72.164  93.283  1.00 121.31 ? 102 ASN A C   1 
ATOM   211   O O   . ASN A 1 102 ? 167.899 72.137  94.504  1.00 120.65 ? 102 ASN A O   1 
ATOM   212   C CB  . ASN A 1 102 ? 169.672 73.852  92.843  1.00 121.43 ? 102 ASN A CB  1 
ATOM   213   C CG  . ASN A 1 102 ? 170.574 73.692  94.060  1.00 121.61 ? 102 ASN A CG  1 
ATOM   214   O OD1 . ASN A 1 102 ? 170.513 74.448  95.017  1.00 121.74 ? 102 ASN A OD1 1 
ATOM   215   N ND2 . ASN A 1 102 ? 171.458 72.727  94.069  1.00 120.82 ? 102 ASN A ND2 1 
ATOM   216   N N   . SER A 1 103 ? 166.611 71.849  92.687  1.00 120.75 ? 103 SER A N   1 
ATOM   217   C CA  . SER A 1 103 ? 165.373 71.419  93.366  1.00 120.64 ? 103 SER A CA  1 
ATOM   218   C C   . SER A 1 103 ? 164.852 72.414  94.416  1.00 120.86 ? 103 SER A C   1 
ATOM   219   O O   . SER A 1 103 ? 164.560 72.043  95.557  1.00 119.69 ? 103 SER A O   1 
ATOM   220   C CB  . SER A 1 103 ? 165.505 69.989  93.916  1.00 120.25 ? 103 SER A CB  1 
ATOM   221   O OG  . SER A 1 103 ? 165.831 69.088  92.875  1.00 120.01 ? 103 SER A OG  1 
ATOM   222   N N   . LYS A 1 104 ? 164.754 73.694  94.030  1.00 118.71 ? 104 LYS A N   1 
ATOM   223   C CA  . LYS A 1 104 ? 164.362 74.836  94.879  1.00 118.04 ? 104 LYS A CA  1 
ATOM   224   C C   . LYS A 1 104 ? 163.277 75.695  94.228  1.00 118.00 ? 104 LYS A C   1 
ATOM   225   O O   . LYS A 1 104 ? 163.092 75.653  93.014  1.00 117.40 ? 104 LYS A O   1 
ATOM   226   C CB  . LYS A 1 104 ? 165.595 75.692  95.210  1.00 117.33 ? 104 LYS A CB  1 
ATOM   227   C CG  . LYS A 1 104 ? 166.438 75.046  96.313  1.00 117.46 ? 104 LYS A CG  1 
ATOM   228   C CD  . LYS A 1 104 ? 167.736 75.814  96.555  1.00 118.29 ? 104 LYS A CD  1 
ATOM   229   C CE  . LYS A 1 104 ? 168.550 75.092  97.634  1.00 118.23 ? 104 LYS A CE  1 
ATOM   230   N NZ  . LYS A 1 104 ? 169.955 75.548  97.658  1.00 116.88 ? 104 LYS A NZ  1 
ATOM   231   N N   . TYR A 1 105 ? 162.579 76.492  95.032  1.00 113.16 ? 105 TYR A N   1 
ATOM   232   C CA  . TYR A 1 105 ? 161.452 77.335  94.613  1.00 112.44 ? 105 TYR A CA  1 
ATOM   233   C C   . TYR A 1 105 ? 161.520 78.745  95.220  1.00 111.33 ? 105 TYR A C   1 
ATOM   234   O O   . TYR A 1 105 ? 162.078 78.948  96.297  1.00 110.97 ? 105 TYR A O   1 
ATOM   235   C CB  . TYR A 1 105 ? 160.127 76.671  95.012  1.00 111.65 ? 105 TYR A CB  1 
ATOM   236   C CG  . TYR A 1 105 ? 160.027 75.178  94.774  1.00 112.52 ? 105 TYR A CG  1 
ATOM   237   C CD1 . TYR A 1 105 ? 159.992 74.669  93.463  1.00 112.11 ? 105 TYR A CD1 1 
ATOM   238   C CD2 . TYR A 1 105 ? 159.974 74.294  95.866  1.00 111.75 ? 105 TYR A CD2 1 
ATOM   239   C CE1 . TYR A 1 105 ? 159.894 73.283  93.251  1.00 111.96 ? 105 TYR A CE1 1 
ATOM   240   C CE2 . TYR A 1 105 ? 159.869 72.909  95.656  1.00 112.68 ? 105 TYR A CE2 1 
ATOM   241   C CZ  . TYR A 1 105 ? 159.832 72.399  94.342  1.00 112.53 ? 105 TYR A CZ  1 
ATOM   242   O OH  . TYR A 1 105 ? 159.749 71.063  94.126  1.00 111.09 ? 105 TYR A OH  1 
ATOM   243   N N   . LEU A 1 106 ? 160.877 79.727  94.584  1.00 104.46 ? 106 LEU A N   1 
ATOM   244   C CA  . LEU A 1 106 ? 160.826 81.111  95.078  1.00 103.94 ? 106 LEU A CA  1 
ATOM   245   C C   . LEU A 1 106 ? 160.076 81.279  96.417  1.00 104.37 ? 106 LEU A C   1 
ATOM   246   O O   . LEU A 1 106 ? 160.266 82.282  97.099  1.00 104.37 ? 106 LEU A O   1 
ATOM   247   C CB  . LEU A 1 106 ? 160.219 82.004  93.985  1.00 103.68 ? 106 LEU A CB  1 
ATOM   248   C CG  . LEU A 1 106 ? 161.068 82.101  92.706  1.00 103.78 ? 106 LEU A CG  1 
ATOM   249   C CD1 . LEU A 1 106 ? 160.368 82.958  91.656  1.00 103.65 ? 106 LEU A CD1 1 
ATOM   250   C CD2 . LEU A 1 106 ? 162.434 82.715  93.001  1.00 104.92 ? 106 LEU A CD2 1 
ATOM   251   N N   . THR A 1 107 ? 159.257 80.302  96.823  1.00 106.89 ? 107 THR A N   1 
ATOM   252   C CA  . THR A 1 107 ? 158.606 80.252  98.148  1.00 106.88 ? 107 THR A CA  1 
ATOM   253   C C   . THR A 1 107 ? 159.551 79.764  99.261  1.00 106.69 ? 107 THR A C   1 
ATOM   254   O O   . THR A 1 107 ? 159.248 79.927  100.443 1.00 106.20 ? 107 THR A O   1 
ATOM   255   C CB  . THR A 1 107 ? 157.332 79.381  98.092  1.00 107.43 ? 107 THR A CB  1 
ATOM   256   O OG1 . THR A 1 107 ? 156.456 79.886  97.115  1.00 107.14 ? 107 THR A OG1 1 
ATOM   257   C CG2 . THR A 1 107 ? 156.505 79.350  99.374  1.00 106.27 ? 107 THR A CG2 1 
ATOM   258   N N   . ASP A 1 108 ? 160.701 79.168  98.931  1.00 110.99 ? 108 ASP A N   1 
ATOM   259   C CA  . ASP A 1 108 ? 161.662 78.665  99.929  1.00 110.82 ? 108 ASP A CA  1 
ATOM   260   C C   . ASP A 1 108 ? 162.332 79.804  100.710 1.00 110.07 ? 108 ASP A C   1 
ATOM   261   O O   . ASP A 1 108 ? 162.618 80.865  100.156 1.00 110.29 ? 108 ASP A O   1 
ATOM   262   C CB  . ASP A 1 108 ? 162.750 77.795  99.279  1.00 110.68 ? 108 ASP A CB  1 
ATOM   263   C CG  . ASP A 1 108 ? 162.233 76.519  98.605  1.00 110.92 ? 108 ASP A CG  1 
ATOM   264   O OD1 . ASP A 1 108 ? 161.136 76.044  98.965  1.00 110.70 ? 108 ASP A OD1 1 
ATOM   265   O OD2 . ASP A 1 108 ? 162.971 75.955  97.772  1.00 111.02 ? 108 ASP A OD2 1 
ATOM   266   N N   . SER A 1 109 ? 162.650 79.563  101.986 1.00 107.64 ? 109 SER A N   1 
ATOM   267   C CA  . SER A 1 109 ? 163.174 80.579  102.919 1.00 108.90 ? 109 SER A CA  1 
ATOM   268   C C   . SER A 1 109 ? 164.374 81.364  102.370 1.00 108.21 ? 109 SER A C   1 
ATOM   269   O O   . SER A 1 109 ? 164.437 82.585  102.529 1.00 107.47 ? 109 SER A O   1 
ATOM   270   C CB  . SER A 1 109 ? 163.537 79.900  104.246 1.00 107.50 ? 109 SER A CB  1 
ATOM   271   O OG  . SER A 1 109 ? 164.004 80.843  105.188 1.00 106.76 ? 109 SER A OG  1 
ATOM   272   N N   . ALA A 1 110 ? 165.271 80.702  101.635 1.00 110.05 ? 110 ALA A N   1 
ATOM   273   C CA  . ALA A 1 110 ? 166.440 81.315  101.005 1.00 109.78 ? 110 ALA A CA  1 
ATOM   274   C C   . ALA A 1 110 ? 166.118 82.509  100.082 1.00 110.38 ? 110 ALA A C   1 
ATOM   275   O O   . ALA A 1 110 ? 166.918 83.438  100.000 1.00 110.68 ? 110 ALA A O   1 
ATOM   276   C CB  . ALA A 1 110 ? 167.171 80.219  100.226 1.00 108.63 ? 110 ALA A CB  1 
ATOM   277   N N   . TYR A 1 111 ? 164.949 82.520  99.427  1.00 107.69 ? 111 TYR A N   1 
ATOM   278   C CA  . TYR A 1 111 ? 164.496 83.597  98.535  1.00 107.38 ? 111 TYR A CA  1 
ATOM   279   C C   . TYR A 1 111 ? 163.562 84.615  99.225  1.00 106.70 ? 111 TYR A C   1 
ATOM   280   O O   . TYR A 1 111 ? 162.856 85.368  98.555  1.00 106.91 ? 111 TYR A O   1 
ATOM   281   C CB  . TYR A 1 111 ? 163.911 82.993  97.248  1.00 107.86 ? 111 TYR A CB  1 
ATOM   282   C CG  . TYR A 1 111 ? 164.941 82.309  96.366  1.00 108.31 ? 111 TYR A CG  1 
ATOM   283   C CD1 . TYR A 1 111 ? 165.776 83.087  95.539  1.00 107.74 ? 111 TYR A CD1 1 
ATOM   284   C CD2 . TYR A 1 111 ? 165.072 80.910  96.369  1.00 109.10 ? 111 TYR A CD2 1 
ATOM   285   C CE1 . TYR A 1 111 ? 166.738 82.473  94.716  1.00 108.56 ? 111 TYR A CE1 1 
ATOM   286   C CE2 . TYR A 1 111 ? 166.050 80.293  95.564  1.00 108.60 ? 111 TYR A CE2 1 
ATOM   287   C CZ  . TYR A 1 111 ? 166.886 81.072  94.737  1.00 109.01 ? 111 TYR A CZ  1 
ATOM   288   O OH  . TYR A 1 111 ? 167.838 80.468  93.979  1.00 109.27 ? 111 TYR A OH  1 
ATOM   289   N N   . THR A 1 112 ? 163.570 84.689  100.561 1.00 98.27  ? 112 THR A N   1 
ATOM   290   C CA  . THR A 1 112 ? 162.725 85.598  101.360 1.00 98.01  ? 112 THR A CA  1 
ATOM   291   C C   . THR A 1 112 ? 163.537 86.599  102.187 1.00 97.99  ? 112 THR A C   1 
ATOM   292   O O   . THR A 1 112 ? 164.683 86.328  102.530 1.00 99.37  ? 112 THR A O   1 
ATOM   293   C CB  . THR A 1 112 ? 161.766 84.833  102.282 1.00 97.28  ? 112 THR A CB  1 
ATOM   294   O OG1 . THR A 1 112 ? 162.438 84.258  103.377 1.00 97.07  ? 112 THR A OG1 1 
ATOM   295   C CG2 . THR A 1 112 ? 160.982 83.733  101.577 1.00 96.67  ? 112 THR A CG2 1 
ATOM   296   N N   . GLU A 1 113 ? 162.945 87.739  102.571 1.00 91.89  ? 113 GLU A N   1 
ATOM   297   C CA  . GLU A 1 113 ? 163.611 88.744  103.430 1.00 91.95  ? 113 GLU A CA  1 
ATOM   298   C C   . GLU A 1 113 ? 163.993 88.223  104.835 1.00 91.71  ? 113 GLU A C   1 
ATOM   299   O O   . GLU A 1 113 ? 164.739 88.884  105.556 1.00 92.32  ? 113 GLU A O   1 
ATOM   300   C CB  . GLU A 1 113 ? 162.770 90.033  103.550 1.00 90.83  ? 113 GLU A CB  1 
ATOM   301   C CG  . GLU A 1 113 ? 162.535 90.742  102.206 1.00 92.23  ? 113 GLU A CG  1 
ATOM   302   C CD  . GLU A 1 113 ? 162.729 92.267  102.265 1.00 93.31  ? 113 GLU A CD  1 
ATOM   303   O OE1 . GLU A 1 113 ? 161.928 92.971  102.918 1.00 92.52  ? 113 GLU A OE1 1 
ATOM   304   O OE2 . GLU A 1 113 ? 163.658 92.780  101.599 1.00 93.27  ? 113 GLU A OE2 1 
ATOM   305   N N   . GLY A 1 114 ? 163.524 87.034  105.228 1.00 85.24  ? 114 GLY A N   1 
ATOM   306   C CA  . GLY A 1 114 ? 164.009 86.276  106.390 1.00 86.53  ? 114 GLY A CA  1 
ATOM   307   C C   . GLY A 1 114 ? 163.502 86.747  107.754 1.00 84.79  ? 114 GLY A C   1 
ATOM   308   O O   . GLY A 1 114 ? 163.080 85.928  108.570 1.00 82.57  ? 114 GLY A O   1 
ATOM   309   N N   . SER A 1 115 ? 163.475 88.057  107.998 1.00 82.00  ? 115 SER A N   1 
ATOM   310   C CA  . SER A 1 115 ? 162.885 88.654  109.204 1.00 82.72  ? 115 SER A CA  1 
ATOM   311   C C   . SER A 1 115 ? 161.360 88.497  109.257 1.00 84.08  ? 115 SER A C   1 
ATOM   312   O O   . SER A 1 115 ? 160.791 88.360  110.339 1.00 80.97  ? 115 SER A O   1 
ATOM   313   C CB  . SER A 1 115 ? 163.274 90.135  109.280 1.00 80.42  ? 115 SER A CB  1 
ATOM   314   O OG  . SER A 1 115 ? 162.872 90.835  108.117 1.00 80.27  ? 115 SER A OG  1 
ATOM   315   N N   . THR A 1 116 ? 160.703 88.468  108.092 1.00 79.80  ? 116 THR A N   1 
ATOM   316   C CA  . THR A 1 116 ? 159.238 88.375  107.942 1.00 77.34  ? 116 THR A CA  1 
ATOM   317   C C   . THR A 1 116 ? 158.763 87.225  107.050 1.00 75.68  ? 116 THR A C   1 
ATOM   318   O O   . THR A 1 116 ? 157.580 86.907  107.046 1.00 77.45  ? 116 THR A O   1 
ATOM   319   C CB  . THR A 1 116 ? 158.679 89.687  107.372 1.00 76.51  ? 116 THR A CB  1 
ATOM   320   O OG1 . THR A 1 116 ? 159.245 89.901  106.097 1.00 76.06  ? 116 THR A OG1 1 
ATOM   321   C CG2 . THR A 1 116 ? 159.011 90.922  108.205 1.00 76.21  ? 116 THR A CG2 1 
ATOM   322   N N   . GLY A 1 117 ? 159.633 86.575  106.267 1.00 77.21  ? 117 GLY A N   1 
ATOM   323   C CA  . GLY A 1 117 ? 159.169 85.560  105.297 1.00 77.79  ? 117 GLY A CA  1 
ATOM   324   C C   . GLY A 1 117 ? 158.531 86.232  104.089 1.00 77.65  ? 117 GLY A C   1 
ATOM   325   O O   . GLY A 1 117 ? 157.624 85.620  103.491 1.00 78.08  ? 117 GLY A O   1 
ATOM   326   N N   . LYS A 1 118 ? 158.982 87.443  103.742 1.00 78.99  ? 118 LYS A N   1 
ATOM   327   C CA  . LYS A 1 118 ? 158.416 88.218  102.598 1.00 78.36  ? 118 LYS A CA  1 
ATOM   328   C C   . LYS A 1 118 ? 159.136 87.804  101.320 1.00 78.60  ? 118 LYS A C   1 
ATOM   329   O O   . LYS A 1 118 ? 160.365 87.628  101.403 1.00 82.27  ? 118 LYS A O   1 
ATOM   330   C CB  . LYS A 1 118 ? 158.581 89.691  102.928 1.00 78.39  ? 118 LYS A CB  1 
ATOM   331   C CG  . LYS A 1 118 ? 158.453 90.720  101.801 1.00 79.70  ? 118 LYS A CG  1 
ATOM   332   C CD  . LYS A 1 118 ? 158.877 92.112  102.212 1.00 80.69  ? 118 LYS A CD  1 
ATOM   333   C CE  . LYS A 1 118 ? 158.951 93.076  101.047 1.00 80.63  ? 118 LYS A CE  1 
ATOM   334   N NZ  . LYS A 1 118 ? 159.438 94.410  101.473 1.00 81.28  ? 118 LYS A NZ  1 
ATOM   335   N N   . THR A 1 119 ? 158.454 87.652  100.185 1.00 80.46  ? 119 THR A N   1 
ATOM   336   C CA  . THR A 1 119 ? 158.999 87.044  98.951  1.00 80.65  ? 119 THR A CA  1 
ATOM   337   C C   . THR A 1 119 ? 159.368 88.057  97.860  1.00 79.21  ? 119 THR A C   1 
ATOM   338   O O   . THR A 1 119 ? 159.017 89.237  97.929  1.00 77.95  ? 119 THR A O   1 
ATOM   339   C CB  . THR A 1 119 ? 158.005 86.015  98.374  1.00 82.00  ? 119 THR A CB  1 
ATOM   340   O OG1 . THR A 1 119 ? 156.851 86.662  97.884  1.00 80.18  ? 119 THR A OG1 1 
ATOM   341   C CG2 . THR A 1 119 ? 157.561 84.970  99.390  1.00 80.48  ? 119 THR A CG2 1 
ATOM   342   N N   . CYS A 1 120 ? 160.028 87.590  96.799  1.00 85.58  ? 120 CYS A N   1 
ATOM   343   C CA  . CYS A 1 120 ? 160.338 88.375  95.604  1.00 87.13  ? 120 CYS A CA  1 
ATOM   344   C C   . CYS A 1 120 ? 159.083 88.937  94.922  1.00 84.99  ? 120 CYS A C   1 
ATOM   345   O O   . CYS A 1 120 ? 159.110 90.076  94.475  1.00 83.99  ? 120 CYS A O   1 
ATOM   346   C CB  . CYS A 1 120 ? 161.145 87.489  94.643  1.00 86.44  ? 120 CYS A CB  1 
ATOM   347   S SG  . CYS A 1 120 ? 160.238 85.961  94.302  1.00 87.55  ? 120 CYS A SG  1 
ATOM   348   N N   . LEU A 1 121 ? 157.965 88.199  94.900  1.00 80.77  ? 121 LEU A N   1 
ATOM   349   C CA  . LEU A 1 121 ? 156.689 88.691  94.363  1.00 80.01  ? 121 LEU A CA  1 
ATOM   350   C C   . LEU A 1 121 ? 156.134 89.854  95.190  1.00 78.17  ? 121 LEU A C   1 
ATOM   351   O O   . LEU A 1 121 ? 155.728 90.861  94.624  1.00 77.39  ? 121 LEU A O   1 
ATOM   352   C CB  . LEU A 1 121 ? 155.687 87.530  94.268  1.00 78.46  ? 121 LEU A CB  1 
ATOM   353   C CG  . LEU A 1 121 ? 154.283 87.947  93.802  1.00 78.65  ? 121 LEU A CG  1 
ATOM   354   C CD1 . LEU A 1 121 ? 154.288 88.475  92.375  1.00 78.23  ? 121 LEU A CD1 1 
ATOM   355   C CD2 . LEU A 1 121 ? 153.353 86.746  93.855  1.00 78.05  ? 121 LEU A CD2 1 
ATOM   356   N N   . MET A 1 122 ? 156.175 89.785  96.521  1.00 73.09  ? 122 MET A N   1 
ATOM   357   C CA  . MET A 1 122 ? 155.802 90.932  97.355  1.00 73.38  ? 122 MET A CA  1 
ATOM   358   C C   . MET A 1 122 ? 156.703 92.136  97.072  1.00 75.13  ? 122 MET A C   1 
ATOM   359   O O   . MET A 1 122 ? 156.213 93.253  96.912  1.00 72.75  ? 122 MET A O   1 
ATOM   360   C CB  . MET A 1 122 ? 155.883 90.569  98.836  1.00 72.11  ? 122 MET A CB  1 
ATOM   361   C CG  . MET A 1 122 ? 154.913 89.460  99.220  1.00 70.76  ? 122 MET A CG  1 
ATOM   362   S SD  . MET A 1 122 ? 155.042 89.022  100.961 1.00 76.71  ? 122 MET A SD  1 
ATOM   363   C CE  . MET A 1 122 ? 154.338 87.368  100.907 1.00 71.77  ? 122 MET A CE  1 
ATOM   364   N N   . LYS A 1 123 ? 158.016 91.913  96.937  1.00 82.09  ? 123 LYS A N   1 
ATOM   365   C CA  . LYS A 1 123 ? 158.970 92.977  96.592  1.00 80.91  ? 123 LYS A CA  1 
ATOM   366   C C   . LYS A 1 123 ? 158.816 93.501  95.151  1.00 79.18  ? 123 LYS A C   1 
ATOM   367   O O   . LYS A 1 123 ? 159.196 94.636  94.896  1.00 79.42  ? 123 LYS A O   1 
ATOM   368   C CB  . LYS A 1 123 ? 160.394 92.506  96.940  1.00 81.91  ? 123 LYS A CB  1 
ATOM   369   C CG  . LYS A 1 123 ? 161.324 93.685  97.249  1.00 82.47  ? 123 LYS A CG  1 
ATOM   370   C CD  . LYS A 1 123 ? 162.584 93.258  98.007  1.00 82.52  ? 123 LYS A CD  1 
ATOM   371   C CE  . LYS A 1 123 ? 163.376 94.499  98.433  1.00 82.96  ? 123 LYS A CE  1 
ATOM   372   N NZ  . LYS A 1 123 ? 164.472 94.190  99.382  1.00 83.82  ? 123 LYS A NZ  1 
ATOM   373   N N   . ALA A 1 124 ? 158.225 92.725  94.243  1.00 79.04  ? 124 ALA A N   1 
ATOM   374   C CA  . ALA A 1 124 ? 157.820 93.150  92.899  1.00 79.68  ? 124 ALA A CA  1 
ATOM   375   C C   . ALA A 1 124 ? 156.529 93.996  92.906  1.00 79.53  ? 124 ALA A C   1 
ATOM   376   O O   . ALA A 1 124 ? 156.399 94.933  92.122  1.00 80.54  ? 124 ALA A O   1 
ATOM   377   C CB  . ALA A 1 124 ? 157.613 91.903  92.030  1.00 78.54  ? 124 ALA A CB  1 
ATOM   378   N N   . VAL A 1 125 ? 155.559 93.656  93.764  1.00 74.40  ? 125 VAL A N   1 
ATOM   379   C CA  . VAL A 1 125 ? 154.295 94.396  93.917  1.00 72.94  ? 125 VAL A CA  1 
ATOM   380   C C   . VAL A 1 125 ? 154.507 95.724  94.662  1.00 73.58  ? 125 VAL A C   1 
ATOM   381   O O   . VAL A 1 125 ? 153.810 96.701  94.404  1.00 73.37  ? 125 VAL A O   1 
ATOM   382   C CB  . VAL A 1 125 ? 153.237 93.505  94.598  1.00 70.50  ? 125 VAL A CB  1 
ATOM   383   C CG1 . VAL A 1 125 ? 151.935 94.245  94.875  1.00 69.26  ? 125 VAL A CG1 1 
ATOM   384   C CG2 . VAL A 1 125 ? 152.860 92.314  93.711  1.00 71.38  ? 125 VAL A CG2 1 
ATOM   385   N N   . LEU A 1 126 ? 155.502 95.816  95.545  1.00 71.90  ? 126 LEU A N   1 
ATOM   386   C CA  . LEU A 1 126 ? 156.024 97.105  96.017  1.00 71.31  ? 126 LEU A CA  1 
ATOM   387   C C   . LEU A 1 126 ? 156.749 97.861  94.883  1.00 74.39  ? 126 LEU A C   1 
ATOM   388   O O   . LEU A 1 126 ? 157.360 97.261  94.008  1.00 77.05  ? 126 LEU A O   1 
ATOM   389   C CB  . LEU A 1 126 ? 156.938 96.868  97.228  1.00 71.57  ? 126 LEU A CB  1 
ATOM   390   C CG  . LEU A 1 126 ? 156.193 96.293  98.446  1.00 69.04  ? 126 LEU A CG  1 
ATOM   391   C CD1 . LEU A 1 126 ? 157.176 95.783  99.487  1.00 67.47  ? 126 LEU A CD1 1 
ATOM   392   C CD2 . LEU A 1 126 ? 155.299 97.343  99.092  1.00 68.13  ? 126 LEU A CD2 1 
ATOM   393   N N   . ASN A 1 127 ? 156.685 99.199  94.897  1.00 81.78  ? 127 ASN A N   1 
ATOM   394   C CA  . ASN A 1 127 ? 157.330 100.044 93.849  1.00 84.68  ? 127 ASN A CA  1 
ATOM   395   C C   . ASN A 1 127 ? 156.815 99.639  92.460  1.00 83.67  ? 127 ASN A C   1 
ATOM   396   O O   . ASN A 1 127 ? 157.560 98.961  91.725  1.00 81.53  ? 127 ASN A O   1 
ATOM   397   C CB  . ASN A 1 127 ? 158.863 100.086 93.967  1.00 84.29  ? 127 ASN A CB  1 
ATOM   398   C CG  . ASN A 1 127 ? 159.549 98.737  93.900  1.00 84.06  ? 127 ASN A CG  1 
ATOM   399   O OD1 . ASN A 1 127 ? 159.921 98.275  92.824  1.00 84.79  ? 127 ASN A OD1 1 
ATOM   400   N ND2 . ASN A 1 127 ? 159.734 98.105  95.047  1.00 82.51  ? 127 ASN A ND2 1 
ATOM   401   N N   . LEU A 1 128 ? 155.587 100.045 92.119  1.00 88.67  ? 128 LEU A N   1 
ATOM   402   C CA  . LEU A 1 128 ? 155.035 99.766  90.764  1.00 86.50  ? 128 LEU A CA  1 
ATOM   403   C C   . LEU A 1 128 ? 155.183 101.029 89.911  1.00 88.71  ? 128 LEU A C   1 
ATOM   404   O O   . LEU A 1 128 ? 154.886 102.124 90.428  1.00 88.00  ? 128 LEU A O   1 
ATOM   405   C CB  . LEU A 1 128 ? 153.564 99.360  90.890  1.00 88.40  ? 128 LEU A CB  1 
ATOM   406   C CG  . LEU A 1 128 ? 153.303 98.067  91.660  1.00 87.99  ? 128 LEU A CG  1 
ATOM   407   C CD1 . LEU A 1 128 ? 151.816 97.749  91.696  1.00 86.78  ? 128 LEU A CD1 1 
ATOM   408   C CD2 . LEU A 1 128 ? 154.078 96.910  91.049  1.00 86.79  ? 128 LEU A CD2 1 
ATOM   409   N N   . GLN A 1 129 ? 155.622 100.882 88.658  1.00 99.13  ? 129 GLN A N   1 
ATOM   410   C CA  . GLN A 1 129 ? 155.848 102.044 87.792  1.00 98.53  ? 129 GLN A CA  1 
ATOM   411   C C   . GLN A 1 129 ? 154.593 102.315 86.951  1.00 98.99  ? 129 GLN A C   1 
ATOM   412   O O   . GLN A 1 129 ? 154.096 101.420 86.269  1.00 99.43  ? 129 GLN A O   1 
ATOM   413   N N   . ASP A 1 130 ? 154.010 103.515 87.024  1.00 98.50  ? 130 ASP A N   1 
ATOM   414   C CA  . ASP A 1 130 ? 152.735 103.839 86.359  1.00 99.35  ? 130 ASP A CA  1 
ATOM   415   C C   . ASP A 1 130 ? 151.581 102.851 86.651  1.00 98.79  ? 130 ASP A C   1 
ATOM   416   O O   . ASP A 1 130 ? 150.698 102.629 85.819  1.00 98.45  ? 130 ASP A O   1 
ATOM   417   C CB  . ASP A 1 130 ? 152.974 104.033 84.862  1.00 98.90  ? 130 ASP A CB  1 
ATOM   418   N N   . GLY A 1 131 ? 151.596 102.224 87.833  1.00 92.19  ? 131 GLY A N   1 
ATOM   419   C CA  . GLY A 1 131 ? 150.609 101.240 88.280  1.00 92.49  ? 131 GLY A CA  1 
ATOM   420   C C   . GLY A 1 131 ? 150.881 99.776  87.903  1.00 92.69  ? 131 GLY A C   1 
ATOM   421   O O   . GLY A 1 131 ? 150.056 98.926  88.230  1.00 92.12  ? 131 GLY A O   1 
ATOM   422   N N   . VAL A 1 132 ? 152.009 99.445  87.261  1.00 93.37  ? 132 VAL A N   1 
ATOM   423   C CA  . VAL A 1 132 ? 152.348 98.070  86.831  1.00 94.39  ? 132 VAL A CA  1 
ATOM   424   C C   . VAL A 1 132 ? 153.836 97.732  87.037  1.00 93.30  ? 132 VAL A C   1 
ATOM   425   O O   . VAL A 1 132 ? 154.672 98.611  87.216  1.00 92.56  ? 132 VAL A O   1 
ATOM   426   C CB  . VAL A 1 132 ? 151.862 97.859  85.381  1.00 95.87  ? 132 VAL A CB  1 
ATOM   427   C CG1 . VAL A 1 132 ? 152.686 98.632  84.352  1.00 94.85  ? 132 VAL A CG1 1 
ATOM   428   C CG2 . VAL A 1 132 ? 151.809 96.384  84.971  1.00 93.64  ? 132 VAL A CG2 1 
ATOM   429   N N   . ASN A 1 133 ? 154.184 96.445  87.035  1.00 94.06  ? 133 ASN A N   1 
ATOM   430   C CA  . ASN A 1 133 ? 155.571 95.979  87.038  1.00 94.69  ? 133 ASN A CA  1 
ATOM   431   C C   . ASN A 1 133 ? 155.725 94.786  86.080  1.00 94.20  ? 133 ASN A C   1 
ATOM   432   O O   . ASN A 1 133 ? 155.158 93.713  86.308  1.00 94.08  ? 133 ASN A O   1 
ATOM   433   C CB  . ASN A 1 133 ? 155.989 95.663  88.485  1.00 94.48  ? 133 ASN A CB  1 
ATOM   434   C CG  . ASN A 1 133 ? 157.417 95.169  88.622  1.00 93.51  ? 133 ASN A CG  1 
ATOM   435   O OD1 . ASN A 1 133 ? 158.069 94.775  87.669  1.00 95.02  ? 133 ASN A OD1 1 
ATOM   436   N ND2 . ASN A 1 133 ? 157.948 95.180  89.812  1.00 92.72  ? 133 ASN A ND2 1 
ATOM   437   N N   . ALA A 1 134 ? 156.517 94.966  85.023  1.00 96.21  ? 134 ALA A N   1 
ATOM   438   C CA  . ALA A 1 134 ? 156.736 93.967  83.974  1.00 96.93  ? 134 ALA A CA  1 
ATOM   439   C C   . ALA A 1 134 ? 157.368 92.651  84.466  1.00 97.70  ? 134 ALA A C   1 
ATOM   440   O O   . ALA A 1 134 ? 157.274 91.637  83.780  1.00 98.40  ? 134 ALA A O   1 
ATOM   441   C CB  . ALA A 1 134 ? 157.605 94.613  82.890  1.00 97.40  ? 134 ALA A CB  1 
ATOM   442   N N   . CYS A 1 135 ? 157.986 92.638  85.649  1.00 97.37  ? 135 CYS A N   1 
ATOM   443   C CA  . CYS A 1 135 ? 158.601 91.454  86.248  1.00 97.56  ? 135 CYS A CA  1 
ATOM   444   C C   . CYS A 1 135 ? 157.593 90.470  86.884  1.00 99.00  ? 135 CYS A C   1 
ATOM   445   O O   . CYS A 1 135 ? 157.894 89.286  87.013  1.00 98.08  ? 135 CYS A O   1 
ATOM   446   C CB  . CYS A 1 135 ? 159.641 91.963  87.252  1.00 98.69  ? 135 CYS A CB  1 
ATOM   447   S SG  . CYS A 1 135 ? 160.697 90.618  87.832  1.00 103.17 ? 135 CYS A SG  1 
ATOM   448   N N   . ILE A 1 136 ? 156.374 90.908  87.242  1.00 96.04  ? 136 ILE A N   1 
ATOM   449   C CA  . ILE A 1 136 ? 155.418 90.064  87.989  1.00 94.57  ? 136 ILE A CA  1 
ATOM   450   C C   . ILE A 1 136 ? 154.996 88.818  87.190  1.00 94.76  ? 136 ILE A C   1 
ATOM   451   O O   . ILE A 1 136 ? 155.077 87.702  87.707  1.00 94.69  ? 136 ILE A O   1 
ATOM   452   C CB  . ILE A 1 136 ? 154.212 90.897  88.486  1.00 94.45  ? 136 ILE A CB  1 
ATOM   453   C CG1 . ILE A 1 136 ? 154.680 91.921  89.542  1.00 93.41  ? 136 ILE A CG1 1 
ATOM   454   C CG2 . ILE A 1 136 ? 153.138 89.986  89.100  1.00 94.90  ? 136 ILE A CG2 1 
ATOM   455   C CD1 . ILE A 1 136 ? 153.611 92.939  89.954  1.00 92.27  ? 136 ILE A CD1 1 
ATOM   456   N N   . MET A 1 137 ? 154.589 88.966  85.922  1.00 98.27  ? 137 MET A N   1 
ATOM   457   C CA  . MET A 1 137 ? 154.254 87.809  85.078  1.00 98.89  ? 137 MET A CA  1 
ATOM   458   C C   . MET A 1 137 ? 155.437 86.828  84.915  1.00 99.81  ? 137 MET A C   1 
ATOM   459   O O   . MET A 1 137 ? 155.247 85.654  85.218  1.00 98.91  ? 137 MET A O   1 
ATOM   460   C CB  . MET A 1 137 ? 153.674 88.238  83.720  1.00 98.90  ? 137 MET A CB  1 
ATOM   461   C CG  . MET A 1 137 ? 152.240 88.745  83.804  1.00 99.18  ? 137 MET A CG  1 
ATOM   462   S SD  . MET A 1 137 ? 151.550 89.155  82.180  1.00 103.27 ? 137 MET A SD  1 
ATOM   463   C CE  . MET A 1 137 ? 149.921 89.777  82.650  1.00 98.88  ? 137 MET A CE  1 
ATOM   464   N N   . PRO A 1 138 ? 156.659 87.255  84.531  1.00 100.30 ? 138 PRO A N   1 
ATOM   465   C CA  . PRO A 1 138 ? 157.858 86.417  84.555  1.00 99.91  ? 138 PRO A CA  1 
ATOM   466   C C   . PRO A 1 138 ? 158.106 85.654  85.861  1.00 100.71 ? 138 PRO A C   1 
ATOM   467   O O   . PRO A 1 138 ? 158.395 84.460  85.804  1.00 100.65 ? 138 PRO A O   1 
ATOM   468   C CB  . PRO A 1 138 ? 159.018 87.366  84.259  1.00 101.14 ? 138 PRO A CB  1 
ATOM   469   C CG  . PRO A 1 138 ? 158.385 88.399  83.342  1.00 100.45 ? 138 PRO A CG  1 
ATOM   470   C CD  . PRO A 1 138 ? 156.961 88.512  83.868  1.00 99.80  ? 138 PRO A CD  1 
ATOM   471   N N   . LEU A 1 139 ? 157.953 86.273  87.039  1.00 98.66  ? 139 LEU A N   1 
ATOM   472   C CA  . LEU A 1 139 ? 158.088 85.566  88.326  1.00 98.69  ? 139 LEU A CA  1 
ATOM   473   C C   . LEU A 1 139 ? 157.054 84.444  88.477  1.00 99.71  ? 139 LEU A C   1 
ATOM   474   O O   . LEU A 1 139 ? 157.399 83.329  88.860  1.00 99.21  ? 139 LEU A O   1 
ATOM   475   C CB  . LEU A 1 139 ? 157.916 86.543  89.501  1.00 99.01  ? 139 LEU A CB  1 
ATOM   476   C CG  . LEU A 1 139 ? 159.049 87.560  89.677  1.00 99.85  ? 139 LEU A CG  1 
ATOM   477   C CD1 . LEU A 1 139 ? 158.584 88.642  90.648  1.00 99.03  ? 139 LEU A CD1 1 
ATOM   478   C CD2 . LEU A 1 139 ? 160.305 86.895  90.248  1.00 100.37 ? 139 LEU A CD2 1 
ATOM   479   N N   . LEU A 1 140 ? 155.786 84.723  88.162  1.00 98.12  ? 140 LEU A N   1 
ATOM   480   C CA  . LEU A 1 140 ? 154.701 83.742  88.233  1.00 98.40  ? 140 LEU A CA  1 
ATOM   481   C C   . LEU A 1 140 ? 154.870 82.626  87.187  1.00 97.90  ? 140 LEU A C   1 
ATOM   482   O O   . LEU A 1 140 ? 154.606 81.462  87.475  1.00 97.83  ? 140 LEU A O   1 
ATOM   483   C CB  . LEU A 1 140 ? 153.357 84.476  88.073  1.00 97.32  ? 140 LEU A CB  1 
ATOM   484   C CG  . LEU A 1 140 ? 153.026 85.443  89.231  1.00 96.23  ? 140 LEU A CG  1 
ATOM   485   C CD1 . LEU A 1 140 ? 151.868 86.356  88.846  1.00 95.62  ? 140 LEU A CD1 1 
ATOM   486   C CD2 . LEU A 1 140 ? 152.646 84.684  90.495  1.00 95.66  ? 140 LEU A CD2 1 
ATOM   487   N N   . GLN A 1 141 ? 155.357 82.949  85.986  1.00 101.73 ? 141 GLN A N   1 
ATOM   488   C CA  . GLN A 1 141 ? 155.725 81.976  84.960  1.00 102.82 ? 141 GLN A CA  1 
ATOM   489   C C   . GLN A 1 141 ? 156.859 81.067  85.449  1.00 102.24 ? 141 GLN A C   1 
ATOM   490   O O   . GLN A 1 141 ? 156.711 79.851  85.420  1.00 102.65 ? 141 GLN A O   1 
ATOM   491   C CB  . GLN A 1 141 ? 156.118 82.703  83.666  1.00 102.16 ? 141 GLN A CB  1 
ATOM   492   C CG  . GLN A 1 141 ? 154.905 83.336  82.964  1.00 102.59 ? 141 GLN A CG  1 
ATOM   493   C CD  . GLN A 1 141 ? 155.275 84.366  81.897  1.00 102.54 ? 141 GLN A CD  1 
ATOM   494   O OE1 . GLN A 1 141 ? 156.427 84.603  81.561  1.00 101.91 ? 141 GLN A OE1 1 
ATOM   495   N NE2 . GLN A 1 141 ? 154.299 85.019  81.306  1.00 101.78 ? 141 GLN A NE2 1 
ATOM   496   N N   . ILE A 1 142 ? 157.954 81.629  85.970  1.00 103.52 ? 142 ILE A N   1 
ATOM   497   C CA  . ILE A 1 142 ? 159.077 80.857  86.525  1.00 104.66 ? 142 ILE A CA  1 
ATOM   498   C C   . ILE A 1 142 ? 158.619 79.979  87.698  1.00 104.15 ? 142 ILE A C   1 
ATOM   499   O O   . ILE A 1 142 ? 159.070 78.844  87.826  1.00 103.82 ? 142 ILE A O   1 
ATOM   500   C CB  . ILE A 1 142 ? 160.232 81.811  86.914  1.00 104.24 ? 142 ILE A CB  1 
ATOM   501   C CG1 . ILE A 1 142 ? 160.883 82.367  85.628  1.00 104.41 ? 142 ILE A CG1 1 
ATOM   502   C CG2 . ILE A 1 142 ? 161.295 81.133  87.792  1.00 103.86 ? 142 ILE A CG2 1 
ATOM   503   C CD1 . ILE A 1 142 ? 161.837 83.534  85.863  1.00 104.64 ? 142 ILE A CD1 1 
ATOM   504   N N   . ASP A 1 143 ? 157.716 80.449  88.559  1.00 103.46 ? 143 ASP A N   1 
ATOM   505   C CA  . ASP A 1 143 ? 157.198 79.643  89.669  1.00 102.99 ? 143 ASP A CA  1 
ATOM   506   C C   . ASP A 1 143 ? 156.360 78.440  89.188  1.00 103.96 ? 143 ASP A C   1 
ATOM   507   O O   . ASP A 1 143 ? 156.569 77.312  89.636  1.00 103.29 ? 143 ASP A O   1 
ATOM   508   C CB  . ASP A 1 143 ? 156.374 80.529  90.608  1.00 102.31 ? 143 ASP A CB  1 
ATOM   509   C CG  . ASP A 1 143 ? 156.036 79.777  91.897  1.00 103.79 ? 143 ASP A CG  1 
ATOM   510   O OD1 . ASP A 1 143 ? 156.974 79.263  92.544  1.00 103.82 ? 143 ASP A OD1 1 
ATOM   511   O OD2 . ASP A 1 143 ? 154.844 79.728  92.265  1.00 103.77 ? 143 ASP A OD2 1 
ATOM   512   N N   . LYS A 1 144 ? 155.454 78.659  88.224  1.00 105.63 ? 144 LYS A N   1 
ATOM   513   C CA  . LYS A 1 144 ? 154.660 77.588  87.586  1.00 104.84 ? 144 LYS A CA  1 
ATOM   514   C C   . LYS A 1 144 ? 155.544 76.606  86.811  1.00 104.99 ? 144 LYS A C   1 
ATOM   515   O O   . LYS A 1 144 ? 155.389 75.395  86.949  1.00 104.31 ? 144 LYS A O   1 
ATOM   516   N N   . ASP A 1 145 ? 156.525 77.108  86.060  1.00 109.07 ? 145 ASP A N   1 
ATOM   517   C CA  . ASP A 1 145 ? 157.523 76.302  85.345  1.00 108.90 ? 145 ASP A CA  1 
ATOM   518   C C   . ASP A 1 145 ? 158.459 75.514  86.281  1.00 108.59 ? 145 ASP A C   1 
ATOM   519   O O   . ASP A 1 145 ? 158.978 74.467  85.894  1.00 109.56 ? 145 ASP A O   1 
ATOM   520   C CB  . ASP A 1 145 ? 158.351 77.197  84.407  1.00 108.84 ? 145 ASP A CB  1 
ATOM   521   C CG  . ASP A 1 145 ? 157.563 77.817  83.240  1.00 108.99 ? 145 ASP A CG  1 
ATOM   522   O OD1 . ASP A 1 145 ? 156.444 77.344  82.930  1.00 109.19 ? 145 ASP A OD1 1 
ATOM   523   O OD2 . ASP A 1 145 ? 158.105 78.724  82.569  1.00 107.95 ? 145 ASP A OD2 1 
ATOM   524   N N   . SER A 1 146 ? 158.657 75.965  87.520  1.00 109.43 ? 146 SER A N   1 
ATOM   525   C CA  . SER A 1 146 ? 159.420 75.232  88.543  1.00 110.01 ? 146 SER A CA  1 
ATOM   526   C C   . SER A 1 146 ? 158.643 74.066  89.173  1.00 109.75 ? 146 SER A C   1 
ATOM   527   O O   . SER A 1 146 ? 159.251 73.222  89.827  1.00 109.08 ? 146 SER A O   1 
ATOM   528   C CB  . SER A 1 146 ? 159.875 76.178  89.661  1.00 110.34 ? 146 SER A CB  1 
ATOM   529   O OG  . SER A 1 146 ? 160.677 77.221  89.154  1.00 111.83 ? 146 SER A OG  1 
ATOM   530   N N   . GLY A 1 147 ? 157.317 73.989  89.008  1.00 107.54 ? 147 GLY A N   1 
ATOM   531   C CA  . GLY A 1 147 ? 156.490 72.936  89.614  1.00 107.60 ? 147 GLY A CA  1 
ATOM   532   C C   . GLY A 1 147 ? 156.316 73.057  91.134  1.00 108.39 ? 147 GLY A C   1 
ATOM   533   O O   . GLY A 1 147 ? 156.177 72.047  91.826  1.00 108.18 ? 147 GLY A O   1 
ATOM   534   N N   . ASN A 1 148 ? 156.362 74.276  91.677  1.00 107.57 ? 148 ASN A N   1 
ATOM   535   C CA  . ASN A 1 148 ? 156.312 74.500  93.149  1.00 107.49 ? 148 ASN A CA  1 
ATOM   536   C C   . ASN A 1 148 ? 154.940 74.121  93.711  1.00 107.05 ? 148 ASN A C   1 
ATOM   537   O O   . ASN A 1 148 ? 153.930 74.663  93.225  1.00 105.15 ? 148 ASN A O   1 
ATOM   538   C CB  . ASN A 1 148 ? 156.657 75.951  93.494  1.00 107.11 ? 148 ASN A CB  1 
ATOM   539   C CG  . ASN A 1 148 ? 156.558 76.266  94.972  1.00 106.35 ? 148 ASN A CG  1 
ATOM   540   O OD1 . ASN A 1 148 ? 156.531 75.366  95.808  1.00 105.86 ? 148 ASN A OD1 1 
ATOM   541   N ND2 . ASN A 1 148 ? 156.513 77.546  95.304  1.00 105.53 ? 148 ASN A ND2 1 
ATOM   542   N N   . PRO A 1 149 ? 154.851 73.221  94.719  1.00 107.28 ? 149 PRO A N   1 
ATOM   543   C CA  . PRO A 1 149 ? 153.568 72.900  95.347  1.00 107.01 ? 149 PRO A CA  1 
ATOM   544   C C   . PRO A 1 149 ? 152.996 74.110  96.100  1.00 106.96 ? 149 PRO A C   1 
ATOM   545   O O   . PRO A 1 149 ? 151.792 74.280  96.080  1.00 106.34 ? 149 PRO A O   1 
ATOM   546   C CB  . PRO A 1 149 ? 153.907 71.792  96.358  1.00 106.71 ? 149 PRO A CB  1 
ATOM   547   C CG  . PRO A 1 149 ? 155.231 71.239  95.881  1.00 106.63 ? 149 PRO A CG  1 
ATOM   548   C CD  . PRO A 1 149 ? 155.950 72.431  95.289  1.00 106.23 ? 149 PRO A CD  1 
ATOM   549   N N   . LYS A 1 150 ? 153.856 74.913  96.736  1.00 105.24 ? 150 LYS A N   1 
ATOM   550   C CA  . LYS A 1 150 ? 153.344 76.034  97.545  1.00 103.39 ? 150 LYS A CA  1 
ATOM   551   C C   . LYS A 1 150 ? 153.480 77.331  96.750  1.00 103.07 ? 150 LYS A C   1 
ATOM   552   O O   . LYS A 1 150 ? 154.434 78.089  96.937  1.00 103.30 ? 150 LYS A O   1 
ATOM   553   C CB  . LYS A 1 150 ? 154.091 76.094  98.889  1.00 102.20 ? 150 LYS A CB  1 
ATOM   554   C CG  . LYS A 1 150 ? 153.799 74.884  99.783  1.00 102.41 ? 150 LYS A CG  1 
ATOM   555   C CD  . LYS A 1 150 ? 154.579 74.966  101.095 1.00 103.25 ? 150 LYS A CD  1 
ATOM   556   C CE  . LYS A 1 150 ? 154.271 73.765  101.986 1.00 103.31 ? 150 LYS A CE  1 
ATOM   557   N NZ  . LYS A 1 150 ? 155.068 73.773  103.223 1.00 103.56 ? 150 LYS A NZ  1 
ATOM   558   N N   . LEU A 1 151 ? 152.553 77.548  95.816  1.00 96.15  ? 151 LEU A N   1 
ATOM   559   C CA  . LEU A 1 151 ? 152.650 78.586  94.785  1.00 96.38  ? 151 LEU A CA  1 
ATOM   560   C C   . LEU A 1 151 ? 152.958 79.976  95.364  1.00 94.37  ? 151 LEU A C   1 
ATOM   561   O O   . LEU A 1 151 ? 152.361 80.407  96.352  1.00 93.23  ? 151 LEU A O   1 
ATOM   562   C CB  . LEU A 1 151 ? 151.352 78.630  93.955  1.00 95.56  ? 151 LEU A CB  1 
ATOM   563   C CG  . LEU A 1 151 ? 151.036 77.361  93.148  1.00 96.59  ? 151 LEU A CG  1 
ATOM   564   C CD1 . LEU A 1 151 ? 149.650 77.483  92.530  1.00 95.10  ? 151 LEU A CD1 1 
ATOM   565   C CD2 . LEU A 1 151 ? 152.036 77.129  92.018  1.00 96.82  ? 151 LEU A CD2 1 
ATOM   566   N N   . LEU A 1 152 ? 153.865 80.699  94.708  1.00 87.55  ? 152 LEU A N   1 
ATOM   567   C CA  . LEU A 1 152 ? 154.400 81.996  95.132  1.00 87.00  ? 152 LEU A CA  1 
ATOM   568   C C   . LEU A 1 152 ? 153.310 83.059  95.328  1.00 86.63  ? 152 LEU A C   1 
ATOM   569   O O   . LEU A 1 152 ? 153.413 83.896  96.219  1.00 86.90  ? 152 LEU A O   1 
ATOM   570   C CB  . LEU A 1 152 ? 155.422 82.426  94.064  1.00 87.73  ? 152 LEU A CB  1 
ATOM   571   C CG  . LEU A 1 152 ? 156.082 83.797  94.253  1.00 86.20  ? 152 LEU A CG  1 
ATOM   572   C CD1 . LEU A 1 152 ? 156.952 83.838  95.503  1.00 86.08  ? 152 LEU A CD1 1 
ATOM   573   C CD2 . LEU A 1 152 ? 156.937 84.108  93.029  1.00 87.20  ? 152 LEU A CD2 1 
ATOM   574   N N   . VAL A 1 153 ? 152.237 83.003  94.536  1.00 77.36  ? 153 VAL A N   1 
ATOM   575   C CA  . VAL A 1 153 ? 151.125 83.964  94.581  1.00 76.09  ? 153 VAL A CA  1 
ATOM   576   C C   . VAL A 1 153 ? 150.376 83.970  95.927  1.00 74.36  ? 153 VAL A C   1 
ATOM   577   O O   . VAL A 1 153 ? 149.869 85.006  96.343  1.00 73.12  ? 153 VAL A O   1 
ATOM   578   C CB  . VAL A 1 153 ? 150.200 83.724  93.373  1.00 73.05  ? 153 VAL A CB  1 
ATOM   579   C CG1 . VAL A 1 153 ? 149.315 82.487  93.519  1.00 74.16  ? 153 VAL A CG1 1 
ATOM   580   C CG2 . VAL A 1 153 ? 149.331 84.942  93.082  1.00 71.94  ? 153 VAL A CG2 1 
ATOM   581   N N   . ASN A 1 154 ? 150.375 82.840  96.643  1.00 72.56  ? 154 ASN A N   1 
ATOM   582   C CA  . ASN A 1 154 ? 149.724 82.661  97.944  1.00 71.99  ? 154 ASN A CA  1 
ATOM   583   C C   . ASN A 1 154 ? 150.719 82.552  99.111  1.00 73.30  ? 154 ASN A C   1 
ATOM   584   O O   . ASN A 1 154 ? 150.326 82.216  100.230 1.00 73.55  ? 154 ASN A O   1 
ATOM   585   C CB  . ASN A 1 154 ? 148.758 81.464  97.866  1.00 72.62  ? 154 ASN A CB  1 
ATOM   586   C CG  . ASN A 1 154 ? 147.628 81.730  96.897  1.00 73.60  ? 154 ASN A CG  1 
ATOM   587   O OD1 . ASN A 1 154 ? 147.132 82.835  96.814  1.00 74.96  ? 154 ASN A OD1 1 
ATOM   588   N ND2 . ASN A 1 154 ? 147.200 80.769  96.119  1.00 73.67  ? 154 ASN A ND2 1 
ATOM   589   N N   . ALA A 1 155 ? 152.000 82.836  98.878  1.00 70.02  ? 155 ALA A N   1 
ATOM   590   C CA  . ALA A 1 155 ? 152.971 82.978  99.956  1.00 67.45  ? 155 ALA A CA  1 
ATOM   591   C C   . ALA A 1 155 ? 152.588 84.165  100.855 1.00 68.85  ? 155 ALA A C   1 
ATOM   592   O O   . ALA A 1 155 ? 152.069 85.180  100.386 1.00 67.66  ? 155 ALA A O   1 
ATOM   593   C CB  . ALA A 1 155 ? 154.376 83.126  99.368  1.00 70.06  ? 155 ALA A CB  1 
ATOM   594   N N   . GLN A 1 156 ? 152.845 84.034  102.152 1.00 63.39  ? 156 GLN A N   1 
ATOM   595   C CA  . GLN A 1 156 ? 152.491 85.039  103.153 1.00 59.38  ? 156 GLN A CA  1 
ATOM   596   C C   . GLN A 1 156 ? 153.656 85.296  104.109 1.00 62.55  ? 156 GLN A C   1 
ATOM   597   O O   . GLN A 1 156 ? 154.477 84.404  104.331 1.00 65.46  ? 156 GLN A O   1 
ATOM   598   C CB  . GLN A 1 156 ? 151.251 84.600  103.924 1.00 58.11  ? 156 GLN A CB  1 
ATOM   599   C CG  . GLN A 1 156 ? 149.955 84.691  103.137 1.00 60.23  ? 156 GLN A CG  1 
ATOM   600   C CD  . GLN A 1 156 ? 148.830 84.073  103.926 1.00 61.86  ? 156 GLN A CD  1 
ATOM   601   O OE1 . GLN A 1 156 ? 148.933 82.950  104.411 1.00 60.25  ? 156 GLN A OE1 1 
ATOM   602   N NE2 . GLN A 1 156 ? 147.748 84.816  104.081 1.00 60.86  ? 156 GLN A NE2 1 
ATOM   603   N N   . CYS A 1 157 ? 153.704 86.475  104.723 1.00 60.25  ? 157 CYS A N   1 
ATOM   604   C CA  . CYS A 1 157 ? 154.591 86.754  105.856 1.00 60.53  ? 157 CYS A CA  1 
ATOM   605   C C   . CYS A 1 157 ? 154.260 85.856  107.069 1.00 63.97  ? 157 CYS A C   1 
ATOM   606   O O   . CYS A 1 157 ? 153.123 85.405  107.234 1.00 65.44  ? 157 CYS A O   1 
ATOM   607   C CB  . CYS A 1 157 ? 154.521 88.237  106.218 1.00 59.44  ? 157 CYS A CB  1 
ATOM   608   S SG  . CYS A 1 157 ? 155.084 89.272  104.841 1.00 66.27  ? 157 CYS A SG  1 
ATOM   609   N N   . THR A 1 158 ? 155.247 85.609  107.931 1.00 64.48  ? 158 THR A N   1 
ATOM   610   C CA  . THR A 1 158 ? 155.230 84.522  108.932 1.00 63.84  ? 158 THR A CA  1 
ATOM   611   C C   . THR A 1 158 ? 155.523 84.995  110.363 1.00 63.94  ? 158 THR A C   1 
ATOM   612   O O   . THR A 1 158 ? 155.221 84.288  111.320 1.00 64.53  ? 158 THR A O   1 
ATOM   613   C CB  . THR A 1 158 ? 156.246 83.440  108.512 1.00 63.89  ? 158 THR A CB  1 
ATOM   614   O OG1 . THR A 1 158 ? 155.981 83.007  107.196 1.00 63.58  ? 158 THR A OG1 1 
ATOM   615   C CG2 . THR A 1 158 ? 156.240 82.179  109.375 1.00 63.35  ? 158 THR A CG2 1 
ATOM   616   N N   . ASP A 1 159 ? 156.095 86.185  110.550 1.00 59.73  ? 159 ASP A N   1 
ATOM   617   C CA  . ASP A 1 159 ? 156.426 86.727  111.877 1.00 61.46  ? 159 ASP A CA  1 
ATOM   618   C C   . ASP A 1 159 ? 155.194 87.171  112.685 1.00 60.26  ? 159 ASP A C   1 
ATOM   619   O O   . ASP A 1 159 ? 154.113 87.378  112.145 1.00 63.11  ? 159 ASP A O   1 
ATOM   620   C CB  . ASP A 1 159 ? 157.373 87.911  111.722 1.00 64.05  ? 159 ASP A CB  1 
ATOM   621   C CG  . ASP A 1 159 ? 156.653 89.098  111.085 1.00 63.66  ? 159 ASP A CG  1 
ATOM   622   O OD1 . ASP A 1 159 ? 156.512 89.105  109.845 1.00 62.13  ? 159 ASP A OD1 1 
ATOM   623   O OD2 . ASP A 1 159 ? 156.214 89.977  111.856 1.00 61.39  ? 159 ASP A OD2 1 
ATOM   624   N N   . GLU A 1 160 ? 155.364 87.388  113.991 1.00 58.47  ? 160 GLU A N   1 
ATOM   625   C CA  . GLU A 1 160 ? 154.278 87.749  114.905 1.00 58.11  ? 160 GLU A CA  1 
ATOM   626   C C   . GLU A 1 160 ? 153.518 89.035  114.525 1.00 60.35  ? 160 GLU A C   1 
ATOM   627   O O   . GLU A 1 160 ? 152.322 89.130  114.793 1.00 60.48  ? 160 GLU A O   1 
ATOM   628   C CB  . GLU A 1 160 ? 154.867 87.849  116.324 1.00 58.56  ? 160 GLU A CB  1 
ATOM   629   C CG  . GLU A 1 160 ? 153.845 88.223  117.404 1.00 60.84  ? 160 GLU A CG  1 
ATOM   630   C CD  . GLU A 1 160 ? 154.359 88.049  118.844 1.00 64.73  ? 160 GLU A CD  1 
ATOM   631   O OE1 . GLU A 1 160 ? 155.575 87.879  119.071 1.00 62.53  ? 160 GLU A OE1 1 
ATOM   632   O OE2 . GLU A 1 160 ? 153.535 88.094  119.773 1.00 64.50  ? 160 GLU A OE2 1 
ATOM   633   N N   . PHE A 1 161 ? 154.160 90.027  113.900 1.00 52.76  ? 161 PHE A N   1 
ATOM   634   C CA  . PHE A 1 161 ? 153.499 91.283  113.541 1.00 48.94  ? 161 PHE A CA  1 
ATOM   635   C C   . PHE A 1 161 ? 152.799 91.218  112.193 1.00 50.48  ? 161 PHE A C   1 
ATOM   636   O O   . PHE A 1 161 ? 151.661 91.681  112.106 1.00 52.55  ? 161 PHE A O   1 
ATOM   637   C CB  . PHE A 1 161 ? 154.461 92.469  113.627 1.00 45.27  ? 161 PHE A CB  1 
ATOM   638   C CG  . PHE A 1 161 ? 154.496 93.034  115.028 1.00 51.87  ? 161 PHE A CG  1 
ATOM   639   C CD1 . PHE A 1 161 ? 155.244 92.399  116.034 1.00 53.50  ? 161 PHE A CD1 1 
ATOM   640   C CD2 . PHE A 1 161 ? 153.694 94.143  115.348 1.00 51.46  ? 161 PHE A CD2 1 
ATOM   641   C CE1 . PHE A 1 161 ? 155.188 92.873  117.355 1.00 54.39  ? 161 PHE A CE1 1 
ATOM   642   C CE2 . PHE A 1 161 ? 153.637 94.617  116.666 1.00 53.28  ? 161 PHE A CE2 1 
ATOM   643   C CZ  . PHE A 1 161 ? 154.385 93.979  117.672 1.00 55.25  ? 161 PHE A CZ  1 
ATOM   644   N N   . TYR A 1 162 ? 153.410 90.624  111.170 1.00 46.24  ? 162 TYR A N   1 
ATOM   645   C CA  . TYR A 1 162 ? 152.855 90.636  109.816 1.00 42.24  ? 162 TYR A CA  1 
ATOM   646   C C   . TYR A 1 162 ? 152.277 89.295  109.338 1.00 49.28  ? 162 TYR A C   1 
ATOM   647   O O   . TYR A 1 162 ? 151.979 89.160  108.157 1.00 49.20  ? 162 TYR A O   1 
ATOM   648   C CB  . TYR A 1 162 ? 153.833 91.285  108.830 1.00 46.28  ? 162 TYR A CB  1 
ATOM   649   C CG  . TYR A 1 162 ? 154.375 92.613  109.322 1.00 48.50  ? 162 TYR A CG  1 
ATOM   650   C CD1 . TYR A 1 162 ? 153.527 93.738  109.376 1.00 47.06  ? 162 TYR A CD1 1 
ATOM   651   C CD2 . TYR A 1 162 ? 155.689 92.708  109.802 1.00 49.83  ? 162 TYR A CD2 1 
ATOM   652   C CE1 . TYR A 1 162 ? 153.994 94.943  109.919 1.00 45.25  ? 162 TYR A CE1 1 
ATOM   653   C CE2 . TYR A 1 162 ? 156.161 93.917  110.350 1.00 45.66  ? 162 TYR A CE2 1 
ATOM   654   C CZ  . TYR A 1 162 ? 155.306 95.031  110.414 1.00 44.97  ? 162 TYR A CZ  1 
ATOM   655   O OH  . TYR A 1 162 ? 155.743 96.187  110.967 1.00 50.00  ? 162 TYR A OH  1 
ATOM   656   N N   . GLN A 1 163 ? 152.063 88.312  110.224 1.00 51.48  ? 163 GLN A N   1 
ATOM   657   C CA  . GLN A 1 163 ? 151.538 86.988  109.866 1.00 51.99  ? 163 GLN A CA  1 
ATOM   658   C C   . GLN A 1 163 ? 150.335 87.043  108.908 1.00 52.81  ? 163 GLN A C   1 
ATOM   659   O O   . GLN A 1 163 ? 149.347 87.732  109.159 1.00 55.12  ? 163 GLN A O   1 
ATOM   660   C CB  . GLN A 1 163 ? 151.168 86.201  111.132 1.00 52.23  ? 163 GLN A CB  1 
ATOM   661   C CG  . GLN A 1 163 ? 150.827 84.737  110.823 1.00 54.51  ? 163 GLN A CG  1 
ATOM   662   C CD  . GLN A 1 163 ? 150.711 83.873  112.072 1.00 57.59  ? 163 GLN A CD  1 
ATOM   663   O OE1 . GLN A 1 163 ? 150.557 84.340  113.190 1.00 55.68  ? 163 GLN A OE1 1 
ATOM   664   N NE2 . GLN A 1 163 ? 150.776 82.572  111.932 1.00 56.54  ? 163 GLN A NE2 1 
ATOM   665   N N   . GLY A 1 164 ? 150.409 86.291  107.814 1.00 52.46  ? 164 GLY A N   1 
ATOM   666   C CA  . GLY A 1 164 ? 149.325 86.161  106.844 1.00 48.54  ? 164 GLY A CA  1 
ATOM   667   C C   . GLY A 1 164 ? 149.224 87.285  105.810 1.00 47.22  ? 164 GLY A C   1 
ATOM   668   O O   . GLY A 1 164 ? 148.413 87.188  104.892 1.00 54.57  ? 164 GLY A O   1 
ATOM   669   N N   . HIS A 1 165 ? 150.122 88.261  105.884 1.00 44.24  ? 165 HIS A N   1 
ATOM   670   C CA  . HIS A 1 165 ? 150.178 89.356  104.881 1.00 42.67  ? 165 HIS A CA  1 
ATOM   671   C C   . HIS A 1 165 ? 150.592 88.753  103.550 1.00 48.32  ? 165 HIS A C   1 
ATOM   672   O O   . HIS A 1 165 ? 151.382 87.829  103.577 1.00 54.20  ? 165 HIS A O   1 
ATOM   673   C CB  . HIS A 1 165 ? 151.121 90.457  105.349 1.00 48.71  ? 165 HIS A CB  1 
ATOM   674   C CG  . HIS A 1 165 ? 151.100 91.711  104.548 1.00 48.72  ? 165 HIS A CG  1 
ATOM   675   N ND1 . HIS A 1 165 ? 149.945 92.233  104.027 1.00 50.04  ? 165 HIS A ND1 1 
ATOM   676   C CD2 . HIS A 1 165 ? 152.087 92.560  104.206 1.00 47.28  ? 165 HIS A CD2 1 
ATOM   677   C CE1 . HIS A 1 165 ? 150.222 93.344  103.384 1.00 49.19  ? 165 HIS A CE1 1 
ATOM   678   N NE2 . HIS A 1 165 ? 151.525 93.569  103.481 1.00 45.32  ? 165 HIS A NE2 1 
ATOM   679   N N   . SER A 1 166 ? 150.119 89.294  102.433 1.00 47.04  ? 166 SER A N   1 
ATOM   680   C CA  . SER A 1 166 ? 150.319 88.660  101.123 1.00 46.49  ? 166 SER A CA  1 
ATOM   681   C C   . SER A 1 166 ? 150.466 89.676  99.992  1.00 47.33  ? 166 SER A C   1 
ATOM   682   O O   . SER A 1 166 ? 150.107 90.843  100.135 1.00 49.33  ? 166 SER A O   1 
ATOM   683   C CB  . SER A 1 166 ? 149.167 87.689  100.829 1.00 51.74  ? 166 SER A CB  1 
ATOM   684   O OG  . SER A 1 166 ? 148.002 88.370  100.411 1.00 52.60  ? 166 SER A OG  1 
ATOM   685   N N   . ALA A 1 167 ? 150.957 89.244  98.829  1.00 47.91  ? 167 ALA A N   1 
ATOM   686   C CA  . ALA A 1 167 ? 151.098 90.116  97.666  1.00 49.85  ? 167 ALA A CA  1 
ATOM   687   C C   . ALA A 1 167 ? 149.769 90.760  97.224  1.00 49.78  ? 167 ALA A C   1 
ATOM   688   O O   . ALA A 1 167 ? 149.765 91.904  96.781  1.00 48.28  ? 167 ALA A O   1 
ATOM   689   C CB  . ALA A 1 167 ? 151.727 89.294  96.535  1.00 49.79  ? 167 ALA A CB  1 
ATOM   690   N N   . LEU A 1 168 ? 148.633 90.075  97.404  1.00 47.31  ? 168 LEU A N   1 
ATOM   691   C CA  . LEU A 1 168 ? 147.308 90.619  97.094  1.00 47.78  ? 168 LEU A CA  1 
ATOM   692   C C   . LEU A 1 168 ? 146.907 91.760  98.042  1.00 42.89  ? 168 LEU A C   1 
ATOM   693   O O   . LEU A 1 168 ? 146.414 92.785  97.585  1.00 42.13  ? 168 LEU A O   1 
ATOM   694   C CB  . LEU A 1 168 ? 146.293 89.464  97.077  1.00 47.83  ? 168 LEU A CB  1 
ATOM   695   C CG  . LEU A 1 168 ? 144.852 89.894  96.749  1.00 47.91  ? 168 LEU A CG  1 
ATOM   696   C CD1 . LEU A 1 168 ? 144.727 90.563  95.383  1.00 42.36  ? 168 LEU A CD1 1 
ATOM   697   C CD2 . LEU A 1 168 ? 143.935 88.677  96.755  1.00 47.90  ? 168 LEU A CD2 1 
ATOM   698   N N   . HIS A 1 169 ? 147.183 91.643  99.343  1.00 37.43  ? 169 HIS A N   1 
ATOM   699   C CA  . HIS A 1 169 ? 147.004 92.755  100.280 1.00 37.14  ? 169 HIS A CA  1 
ATOM   700   C C   . HIS A 1 169 ? 147.856 93.965  99.893  1.00 41.28  ? 169 HIS A C   1 
ATOM   701   O O   . HIS A 1 169 ? 147.327 95.093  99.948  1.00 41.83  ? 169 HIS A O   1 
ATOM   702   C CB  . HIS A 1 169 ? 147.340 92.295  101.707 1.00 38.00  ? 169 HIS A CB  1 
ATOM   703   C CG  . HIS A 1 169 ? 146.325 91.381  102.311 1.00 40.71  ? 169 HIS A CG  1 
ATOM   704   N ND1 . HIS A 1 169 ? 146.637 90.097  102.716 1.00 38.21  ? 169 HIS A ND1 1 
ATOM   705   C CD2 . HIS A 1 169 ? 145.016 91.559  102.590 1.00 37.10  ? 169 HIS A CD2 1 
ATOM   706   C CE1 . HIS A 1 169 ? 145.561 89.521  103.215 1.00 37.16  ? 169 HIS A CE1 1 
ATOM   707   N NE2 . HIS A 1 169 ? 144.553 90.399  103.150 1.00 40.97  ? 169 HIS A NE2 1 
ATOM   708   N N   . ILE A 1 170 ? 149.113 93.747  99.495  1.00 45.07  ? 170 ILE A N   1 
ATOM   709   C CA  . ILE A 1 170 ? 149.998 94.825  99.029  1.00 40.02  ? 170 ILE A CA  1 
ATOM   710   C C   . ILE A 1 170 ? 149.460 95.465  97.745  1.00 43.81  ? 170 ILE A C   1 
ATOM   711   O O   . ILE A 1 170 ? 149.404 96.688  97.670  1.00 44.41  ? 170 ILE A O   1 
ATOM   712   C CB  . ILE A 1 170 ? 151.452 94.341  98.857  1.00 47.81  ? 170 ILE A CB  1 
ATOM   713   C CG1 . ILE A 1 170 ? 152.011 93.740  100.161 1.00 44.88  ? 170 ILE A CG1 1 
ATOM   714   C CG2 . ILE A 1 170 ? 152.365 95.500  98.428  1.00 45.86  ? 170 ILE A CG2 1 
ATOM   715   C CD1 . ILE A 1 170 ? 153.327 92.985  99.976  1.00 46.62  ? 170 ILE A CD1 1 
ATOM   716   N N   . ALA A 1 171 ? 149.025 94.686  96.750  1.00 42.00  ? 171 ALA A N   1 
ATOM   717   C CA  . ALA A 1 171 ? 148.471 95.221  95.507  1.00 39.18  ? 171 ALA A CA  1 
ATOM   718   C C   . ALA A 1 171 ? 147.222 96.088  95.746  1.00 43.51  ? 171 ALA A C   1 
ATOM   719   O O   . ALA A 1 171 ? 147.076 97.151  95.143  1.00 41.92  ? 171 ALA A O   1 
ATOM   720   C CB  . ALA A 1 171 ? 148.157 94.051  94.573  1.00 40.49  ? 171 ALA A CB  1 
ATOM   721   N N   . ILE A 1 172 ? 146.347 95.656  96.661  1.00 46.49  ? 172 ILE A N   1 
ATOM   722   C CA  . ILE A 1 172 ? 145.160 96.411  97.063  1.00 39.84  ? 172 ILE A CA  1 
ATOM   723   C C   . ILE A 1 172 ? 145.567 97.706  97.764  1.00 42.36  ? 172 ILE A C   1 
ATOM   724   O O   . ILE A 1 172 ? 145.147 98.766  97.323  1.00 43.71  ? 172 ILE A O   1 
ATOM   725   C CB  . ILE A 1 172 ? 144.212 95.542  97.912  1.00 40.89  ? 172 ILE A CB  1 
ATOM   726   C CG1 . ILE A 1 172 ? 143.668 94.393  97.041  1.00 42.53  ? 172 ILE A CG1 1 
ATOM   727   C CG2 . ILE A 1 172 ? 143.039 96.351  98.486  1.00 34.68  ? 172 ILE A CG2 1 
ATOM   728   C CD1 . ILE A 1 172 ? 142.948 93.310  97.823  1.00 40.21  ? 172 ILE A CD1 1 
ATOM   729   N N   . GLU A 1 173 ? 146.421 97.682  98.785  1.00 40.71  ? 173 GLU A N   1 
ATOM   730   C CA  . GLU A 1 173 ? 146.862 98.912  99.468  1.00 38.66  ? 173 GLU A CA  1 
ATOM   731   C C   . GLU A 1 173 ? 147.664 99.857  98.551  1.00 44.94  ? 173 GLU A C   1 
ATOM   732   O O   . GLU A 1 173 ? 147.515 101.075 98.643  1.00 46.37  ? 173 GLU A O   1 
ATOM   733   C CB  . GLU A 1 173 ? 147.621 98.525  100.744 1.00 44.81  ? 173 GLU A CB  1 
ATOM   734   C CG  . GLU A 1 173 ? 148.462 99.614  101.432 1.00 46.59  ? 173 GLU A CG  1 
ATOM   735   C CD  . GLU A 1 173 ? 147.821 100.996 101.589 1.00 49.52  ? 173 GLU A CD  1 
ATOM   736   O OE1 . GLU A 1 173 ? 146.578 101.088 101.728 1.00 51.02  ? 173 GLU A OE1 1 
ATOM   737   O OE2 . GLU A 1 173 ? 148.590 101.983 101.629 1.00 46.27  ? 173 GLU A OE2 1 
ATOM   738   N N   . LYS A 1 174 ? 148.453 99.350  97.596  1.00 48.54  ? 174 LYS A N   1 
ATOM   739   C CA  . LYS A 1 174 ? 149.109 100.159 96.553  1.00 44.59  ? 174 LYS A CA  1 
ATOM   740   C C   . LYS A 1 174 ? 148.158 100.671 95.457  1.00 47.17  ? 174 LYS A C   1 
ATOM   741   O O   . LYS A 1 174 ? 148.604 101.363 94.546  1.00 50.48  ? 174 LYS A O   1 
ATOM   742   C CB  . LYS A 1 174 ? 150.320 99.403  95.983  1.00 46.75  ? 174 LYS A CB  1 
ATOM   743   C CG  . LYS A 1 174 ? 151.500 99.305  96.973  1.00 48.95  ? 174 LYS A CG  1 
ATOM   744   C CD  . LYS A 1 174 ? 152.193 100.659 97.178  1.00 47.01  ? 174 LYS A CD  1 
ATOM   745   C CE  . LYS A 1 174 ? 153.333 100.576 98.199  1.00 48.20  ? 174 LYS A CE  1 
ATOM   746   N NZ  . LYS A 1 174 ? 153.861 101.927 98.515  1.00 50.28  ? 174 LYS A NZ  1 
ATOM   747   N N   . ARG A 1 175 ? 146.854 100.380 95.560  1.00 46.26  ? 175 ARG A N   1 
ATOM   748   C CA  . ARG A 1 175 ? 145.746 100.864 94.709  1.00 40.97  ? 175 ARG A CA  1 
ATOM   749   C C   . ARG A 1 175 ? 145.839 100.472 93.228  1.00 45.43  ? 175 ARG A C   1 
ATOM   750   O O   . ARG A 1 175 ? 145.256 101.142 92.378  1.00 48.21  ? 175 ARG A O   1 
ATOM   751   C CB  . ARG A 1 175 ? 145.472 102.368 94.937  1.00 42.41  ? 175 ARG A CB  1 
ATOM   752   C CG  . ARG A 1 175 ? 145.306 102.745 96.412  1.00 42.95  ? 175 ARG A CG  1 
ATOM   753   C CD  . ARG A 1 175 ? 144.918 104.212 96.636  1.00 41.98  ? 175 ARG A CD  1 
ATOM   754   N NE  . ARG A 1 175 ? 143.520 104.518 96.272  1.00 46.21  ? 175 ARG A NE  1 
ATOM   755   C CZ  . ARG A 1 175 ? 142.449 104.412 97.036  1.00 48.84  ? 175 ARG A CZ  1 
ATOM   756   N NH1 . ARG A 1 175 ? 141.297 104.850 96.635  1.00 46.57  ? 175 ARG A NH1 1 
ATOM   757   N NH2 . ARG A 1 175 ? 142.497 103.853 98.205  1.00 45.51  ? 175 ARG A NH2 1 
ATOM   758   N N   . SER A 1 176 ? 146.541 99.387  92.901  1.00 53.84  ? 176 SER A N   1 
ATOM   759   C CA  . SER A 1 176 ? 146.659 98.903  91.520  1.00 55.41  ? 176 SER A CA  1 
ATOM   760   C C   . SER A 1 176 ? 145.632 97.816  91.210  1.00 59.60  ? 176 SER A C   1 
ATOM   761   O O   . SER A 1 176 ? 145.841 96.634  91.482  1.00 62.21  ? 176 SER A O   1 
ATOM   762   C CB  . SER A 1 176 ? 148.082 98.433  91.219  1.00 57.59  ? 176 SER A CB  1 
ATOM   763   O OG  . SER A 1 176 ? 148.136 97.942  89.891  1.00 60.39  ? 176 SER A OG  1 
ATOM   764   N N   . LEU A 1 177 ? 144.521 98.200  90.579  1.00 53.30  ? 177 LEU A N   1 
ATOM   765   C CA  . LEU A 1 177 ? 143.557 97.244  90.040  1.00 54.95  ? 177 LEU A CA  1 
ATOM   766   C C   . LEU A 1 177 ? 144.180 96.368  88.942  1.00 58.77  ? 177 LEU A C   1 
ATOM   767   O O   . LEU A 1 177 ? 143.883 95.181  88.873  1.00 60.49  ? 177 LEU A O   1 
ATOM   768   C CB  . LEU A 1 177 ? 142.322 98.014  89.556  1.00 58.41  ? 177 LEU A CB  1 
ATOM   769   C CG  . LEU A 1 177 ? 141.244 97.144  88.890  1.00 58.50  ? 177 LEU A CG  1 
ATOM   770   C CD1 . LEU A 1 177 ? 140.702 96.067  89.826  1.00 55.66  ? 177 LEU A CD1 1 
ATOM   771   C CD2 . LEU A 1 177 ? 140.088 98.040  88.467  1.00 55.77  ? 177 LEU A CD2 1 
ATOM   772   N N   . GLN A 1 178 ? 145.099 96.907  88.138  1.00 60.63  ? 178 GLN A N   1 
ATOM   773   C CA  . GLN A 1 178 ? 145.884 96.147  87.162  1.00 57.39  ? 178 GLN A CA  1 
ATOM   774   C C   . GLN A 1 178 ? 146.654 95.000  87.824  1.00 59.61  ? 178 GLN A C   1 
ATOM   775   O O   . GLN A 1 178 ? 146.622 93.870  87.347  1.00 60.93  ? 178 GLN A O   1 
ATOM   776   C CB  . GLN A 1 178 ? 146.873 97.076  86.431  1.00 60.02  ? 178 GLN A CB  1 
ATOM   777   C CG  . GLN A 1 178 ? 146.232 98.193  85.591  1.00 60.93  ? 178 GLN A CG  1 
ATOM   778   C CD  . GLN A 1 178 ? 146.006 99.510  86.331  1.00 63.10  ? 178 GLN A CD  1 
ATOM   779   O OE1 . GLN A 1 178 ? 145.736 99.566  87.521  1.00 63.21  ? 178 GLN A OE1 1 
ATOM   780   N NE2 . GLN A 1 178 ? 146.086 100.630 85.649  1.00 62.38  ? 178 GLN A NE2 1 
ATOM   781   N N   . CYS A 1 179 ? 147.320 95.264  88.949  1.00 57.63  ? 179 CYS A N   1 
ATOM   782   C CA  . CYS A 1 179 ? 148.060 94.250  89.689  1.00 58.37  ? 179 CYS A CA  1 
ATOM   783   C C   . CYS A 1 179 ? 147.131 93.260  90.413  1.00 61.15  ? 179 CYS A C   1 
ATOM   784   O O   . CYS A 1 179 ? 147.387 92.058  90.387  1.00 58.28  ? 179 CYS A O   1 
ATOM   785   C CB  . CYS A 1 179 ? 149.023 94.972  90.636  1.00 57.64  ? 179 CYS A CB  1 
ATOM   786   S SG  . CYS A 1 179 ? 150.188 93.796  91.355  1.00 65.71  ? 179 CYS A SG  1 
ATOM   787   N N   . VAL A 1 180 ? 146.007 93.718  90.983  1.00 56.94  ? 180 VAL A N   1 
ATOM   788   C CA  . VAL A 1 180 ? 144.987 92.833  91.575  1.00 55.94  ? 180 VAL A CA  1 
ATOM   789   C C   . VAL A 1 180 ? 144.418 91.869  90.534  1.00 55.90  ? 180 VAL A C   1 
ATOM   790   O O   . VAL A 1 180 ? 144.399 90.662  90.771  1.00 51.90  ? 180 VAL A O   1 
ATOM   791   C CB  . VAL A 1 180 ? 143.864 93.643  92.255  1.00 56.80  ? 180 VAL A CB  1 
ATOM   792   C CG1 . VAL A 1 180 ? 142.682 92.766  92.668  1.00 56.73  ? 180 VAL A CG1 1 
ATOM   793   C CG2 . VAL A 1 180 ? 144.389 94.338  93.513  1.00 50.70  ? 180 VAL A CG2 1 
ATOM   794   N N   . LYS A 1 181 ? 144.028 92.364  89.351  1.00 57.73  ? 181 LYS A N   1 
ATOM   795   C CA  . LYS A 1 181 ? 143.590 91.534  88.226  1.00 54.72  ? 181 LYS A CA  1 
ATOM   796   C C   . LYS A 1 181 ? 144.646 90.496  87.849  1.00 56.10  ? 181 LYS A C   1 
ATOM   797   O O   . LYS A 1 181 ? 144.337 89.316  87.760  1.00 58.39  ? 181 LYS A O   1 
ATOM   798   C CB  . LYS A 1 181 ? 143.262 92.412  87.010  1.00 54.77  ? 181 LYS A CB  1 
ATOM   799   C CG  . LYS A 1 181 ? 141.929 93.149  87.156  1.00 57.95  ? 181 LYS A CG  1 
ATOM   800   C CD  . LYS A 1 181 ? 141.649 94.034  85.943  1.00 55.32  ? 181 LYS A CD  1 
ATOM   801   C CE  . LYS A 1 181 ? 140.265 94.671  86.065  1.00 58.46  ? 181 LYS A CE  1 
ATOM   802   N NZ  . LYS A 1 181 ? 139.900 95.423  84.845  1.00 59.62  ? 181 LYS A NZ  1 
ATOM   803   N N   . LEU A 1 182 ? 145.897 90.923  87.681  1.00 62.48  ? 182 LEU A N   1 
ATOM   804   C CA  . LEU A 1 182 ? 147.021 90.061  87.309  1.00 63.59  ? 182 LEU A CA  1 
ATOM   805   C C   . LEU A 1 182 ? 147.260 88.937  88.334  1.00 64.68  ? 182 LEU A C   1 
ATOM   806   O O   . LEU A 1 182 ? 147.439 87.783  87.952  1.00 65.73  ? 182 LEU A O   1 
ATOM   807   C CB  . LEU A 1 182 ? 148.240 90.989  87.118  1.00 63.05  ? 182 LEU A CB  1 
ATOM   808   C CG  . LEU A 1 182 ? 149.453 90.435  86.359  1.00 64.99  ? 182 LEU A CG  1 
ATOM   809   C CD1 . LEU A 1 182 ? 150.392 91.604  86.081  1.00 65.72  ? 182 LEU A CD1 1 
ATOM   810   C CD2 . LEU A 1 182 ? 150.241 89.386  87.130  1.00 64.85  ? 182 LEU A CD2 1 
ATOM   811   N N   . LEU A 1 183 ? 147.215 89.247  89.629  1.00 62.07  ? 183 LEU A N   1 
ATOM   812   C CA  . LEU A 1 183 ? 147.353 88.267  90.710  1.00 62.44  ? 183 LEU A CA  1 
ATOM   813   C C   . LEU A 1 183 ? 146.164 87.296  90.775  1.00 62.36  ? 183 LEU A C   1 
ATOM   814   O O   . LEU A 1 183 ? 146.361 86.085  90.867  1.00 62.52  ? 183 LEU A O   1 
ATOM   815   C CB  . LEU A 1 183 ? 147.526 89.018  92.041  1.00 64.28  ? 183 LEU A CB  1 
ATOM   816   C CG  . LEU A 1 183 ? 148.869 89.754  92.210  1.00 63.77  ? 183 LEU A CG  1 
ATOM   817   C CD1 . LEU A 1 183 ? 148.795 90.623  93.459  1.00 59.74  ? 183 LEU A CD1 1 
ATOM   818   C CD2 . LEU A 1 183 ? 150.042 88.799  92.390  1.00 63.64  ? 183 LEU A CD2 1 
ATOM   819   N N   . VAL A 1 184 ? 144.927 87.793  90.691  1.00 65.58  ? 184 VAL A N   1 
ATOM   820   C CA  . VAL A 1 184 ? 143.720 86.955  90.771  1.00 65.10  ? 184 VAL A CA  1 
ATOM   821   C C   . VAL A 1 184 ? 143.572 86.048  89.542  1.00 66.00  ? 184 VAL A C   1 
ATOM   822   O O   . VAL A 1 184 ? 143.276 84.866  89.696  1.00 66.98  ? 184 VAL A O   1 
ATOM   823   C CB  . VAL A 1 184 ? 142.483 87.835  91.029  1.00 62.91  ? 184 VAL A CB  1 
ATOM   824   C CG1 . VAL A 1 184 ? 141.165 87.072  90.893  1.00 61.25  ? 184 VAL A CG1 1 
ATOM   825   C CG2 . VAL A 1 184 ? 142.535 88.397  92.457  1.00 61.08  ? 184 VAL A CG2 1 
ATOM   826   N N   . GLU A 1 185 ? 143.892 86.533  88.339  1.00 64.04  ? 185 GLU A N   1 
ATOM   827   C CA  . GLU A 1 185 ? 144.014 85.701  87.131  1.00 63.27  ? 185 GLU A CA  1 
ATOM   828   C C   . GLU A 1 185 ? 145.010 84.542  87.284  1.00 67.14  ? 185 GLU A C   1 
ATOM   829   O O   . GLU A 1 185 ? 144.838 83.492  86.667  1.00 68.44  ? 185 GLU A O   1 
ATOM   830   C CB  . GLU A 1 185 ? 144.469 86.574  85.949  1.00 64.04  ? 185 GLU A CB  1 
ATOM   831   C CG  . GLU A 1 185 ? 143.354 87.473  85.400  1.00 64.30  ? 185 GLU A CG  1 
ATOM   832   C CD  . GLU A 1 185 ? 143.865 88.647  84.544  1.00 67.63  ? 185 GLU A CD  1 
ATOM   833   O OE1 . GLU A 1 185 ? 145.024 88.627  84.073  1.00 67.54  ? 185 GLU A OE1 1 
ATOM   834   O OE2 . GLU A 1 185 ? 143.069 89.579  84.280  1.00 67.10  ? 185 GLU A OE2 1 
ATOM   835   N N   . ASN A 1 186 ? 146.050 84.710  88.107  1.00 67.55  ? 186 ASN A N   1 
ATOM   836   C CA  . ASN A 1 186 ? 147.087 83.710  88.365  1.00 66.16  ? 186 ASN A CA  1 
ATOM   837   C C   . ASN A 1 186 ? 146.861 82.877  89.643  1.00 67.95  ? 186 ASN A C   1 
ATOM   838   O O   . ASN A 1 186 ? 147.753 82.147  90.070  1.00 68.18  ? 186 ASN A O   1 
ATOM   839   C CB  . ASN A 1 186 ? 148.459 84.392  88.303  1.00 67.82  ? 186 ASN A CB  1 
ATOM   840   C CG  . ASN A 1 186 ? 148.876 84.606  86.867  1.00 69.56  ? 186 ASN A CG  1 
ATOM   841   O OD1 . ASN A 1 186 ? 149.395 83.704  86.219  1.00 71.14  ? 186 ASN A OD1 1 
ATOM   842   N ND2 . ASN A 1 186 ? 148.654 85.774  86.316  1.00 68.22  ? 186 ASN A ND2 1 
ATOM   843   N N   . GLY A 1 187 ? 145.677 82.941  90.253  1.00 67.30  ? 187 GLY A N   1 
ATOM   844   C CA  . GLY A 1 187 ? 145.307 82.073  91.375  1.00 65.30  ? 187 GLY A CA  1 
ATOM   845   C C   . GLY A 1 187 ? 145.598 82.626  92.774  1.00 66.03  ? 187 GLY A C   1 
ATOM   846   O O   . GLY A 1 187 ? 145.719 81.842  93.719  1.00 64.72  ? 187 GLY A O   1 
ATOM   847   N N   . ALA A 1 188 ? 145.694 83.950  92.936  1.00 65.30  ? 188 ALA A N   1 
ATOM   848   C CA  . ALA A 1 188 ? 145.698 84.575  94.259  1.00 62.54  ? 188 ALA A CA  1 
ATOM   849   C C   . ALA A 1 188 ? 144.411 84.242  95.035  1.00 65.14  ? 188 ALA A C   1 
ATOM   850   O O   . ALA A 1 188 ? 143.306 84.542  94.589  1.00 67.46  ? 188 ALA A O   1 
ATOM   851   C CB  . ALA A 1 188 ? 145.862 86.089  94.120  1.00 61.67  ? 188 ALA A CB  1 
ATOM   852   N N   . ASP A 1 189 ? 144.550 83.636  96.208  1.00 62.71  ? 189 ASP A N   1 
ATOM   853   C CA  . ASP A 1 189 ? 143.441 83.339  97.107  1.00 57.50  ? 189 ASP A CA  1 
ATOM   854   C C   . ASP A 1 189 ? 142.913 84.630  97.749  1.00 61.34  ? 189 ASP A C   1 
ATOM   855   O O   . ASP A 1 189 ? 143.610 85.313  98.498  1.00 63.15  ? 189 ASP A O   1 
ATOM   856   C CB  . ASP A 1 189 ? 143.886 82.308  98.155  1.00 56.93  ? 189 ASP A CB  1 
ATOM   857   C CG  . ASP A 1 189 ? 142.764 81.912  99.127  1.00 63.87  ? 189 ASP A CG  1 
ATOM   858   O OD1 . ASP A 1 189 ? 141.605 82.328  98.914  1.00 65.06  ? 189 ASP A OD1 1 
ATOM   859   O OD2 . ASP A 1 189 ? 143.043 81.142  100.070 1.00 64.28  ? 189 ASP A OD2 1 
ATOM   860   N N   . VAL A 1 190 ? 141.661 84.969  97.460  1.00 55.81  ? 190 VAL A N   1 
ATOM   861   C CA  . VAL A 1 190 ? 141.016 86.190  97.947  1.00 52.62  ? 190 VAL A CA  1 
ATOM   862   C C   . VAL A 1 190 ? 140.597 86.079  99.423  1.00 51.90  ? 190 VAL A C   1 
ATOM   863   O O   . VAL A 1 190 ? 140.160 87.057  100.015 1.00 54.55  ? 190 VAL A O   1 
ATOM   864   C CB  . VAL A 1 190 ? 139.861 86.595  97.006  1.00 53.18  ? 190 VAL A CB  1 
ATOM   865   C CG1 . VAL A 1 190 ? 139.377 88.018  97.271  1.00 55.26  ? 190 VAL A CG1 1 
ATOM   866   C CG2 . VAL A 1 190 ? 140.291 86.568  95.534  1.00 50.73  ? 190 VAL A CG2 1 
ATOM   867   N N   . HIS A 1 191 ? 140.754 84.911  100.056 1.00 53.07  ? 191 HIS A N   1 
ATOM   868   C CA  . HIS A 1 191 ? 140.368 84.659  101.450 1.00 51.70  ? 191 HIS A CA  1 
ATOM   869   C C   . HIS A 1 191 ? 141.544 84.501  102.422 1.00 53.46  ? 191 HIS A C   1 
ATOM   870   O O   . HIS A 1 191 ? 141.374 83.946  103.508 1.00 55.90  ? 191 HIS A O   1 
ATOM   871   C CB  . HIS A 1 191 ? 139.432 83.441  101.501 1.00 55.35  ? 191 HIS A CB  1 
ATOM   872   C CG  . HIS A 1 191 ? 138.199 83.619  100.679 1.00 56.76  ? 191 HIS A CG  1 
ATOM   873   N ND1 . HIS A 1 191 ? 137.022 84.112  101.209 1.00 53.20  ? 191 HIS A ND1 1 
ATOM   874   C CD2 . HIS A 1 191 ? 137.957 83.386  99.370  1.00 54.86  ? 191 HIS A CD2 1 
ATOM   875   C CE1 . HIS A 1 191 ? 136.106 84.170  100.263 1.00 54.53  ? 191 HIS A CE1 1 
ATOM   876   N NE2 . HIS A 1 191 ? 136.657 83.730  99.125  1.00 56.23  ? 191 HIS A NE2 1 
ATOM   877   N N   . LEU A 1 192 ? 142.748 84.971  102.078 1.00 55.46  ? 192 LEU A N   1 
ATOM   878   C CA  . LEU A 1 192 ? 143.882 84.994  103.013 1.00 50.97  ? 192 LEU A CA  1 
ATOM   879   C C   . LEU A 1 192 ? 143.671 86.033  104.124 1.00 50.27  ? 192 LEU A C   1 
ATOM   880   O O   . LEU A 1 192 ? 143.362 87.188  103.839 1.00 51.79  ? 192 LEU A O   1 
ATOM   881   C CB  . LEU A 1 192 ? 145.185 85.291  102.249 1.00 50.96  ? 192 LEU A CB  1 
ATOM   882   C CG  . LEU A 1 192 ? 145.556 84.249  101.182 1.00 55.37  ? 192 LEU A CG  1 
ATOM   883   C CD1 . LEU A 1 192 ? 146.832 84.674  100.462 1.00 53.04  ? 192 LEU A CD1 1 
ATOM   884   C CD2 . LEU A 1 192 ? 145.776 82.863  101.778 1.00 53.25  ? 192 LEU A CD2 1 
ATOM   885   N N   . ARG A 1 193 ? 143.984 85.668  105.380 1.00 46.32  ? 193 ARG A N   1 
ATOM   886   C CA  . ARG A 1 193 ? 143.760 86.608  106.522 1.00 45.39  ? 193 ARG A CA  1 
ATOM   887   C C   . ARG A 1 193 ? 145.037 87.210  107.098 1.00 45.01  ? 193 ARG A C   1 
ATOM   888   O O   . ARG A 1 193 ? 145.723 86.506  107.866 1.00 49.62  ? 193 ARG A O   1 
ATOM   889   C CB  . ARG A 1 193 ? 143.112 85.954  107.757 1.00 51.26  ? 193 ARG A CB  1 
ATOM   890   C CG  . ARG A 1 193 ? 141.591 85.763  107.718 1.00 44.87  ? 193 ARG A CG  1 
ATOM   891   C CD  . ARG A 1 193 ? 141.150 84.663  106.754 1.00 48.83  ? 193 ARG A CD  1 
ATOM   892   N NE  . ARG A 1 193 ? 139.699 84.632  106.635 1.00 52.18  ? 193 ARG A NE  1 
ATOM   893   C CZ  . ARG A 1 193 ? 139.018 83.778  105.879 1.00 49.70  ? 193 ARG A CZ  1 
ATOM   894   N NH1 . ARG A 1 193 ? 137.698 83.837  105.840 1.00 48.34  ? 193 ARG A NH1 1 
ATOM   895   N NH2 . ARG A 1 193 ? 139.658 82.871  105.164 1.00 48.53  ? 193 ARG A NH2 1 
ATOM   896   N N   . ALA A 1 194 ? 145.340 88.453  106.749 1.00 37.89  ? 194 ALA A N   1 
ATOM   897   C CA  . ALA A 1 194 ? 146.416 89.200  107.390 1.00 32.82  ? 194 ALA A CA  1 
ATOM   898   C C   . ALA A 1 194 ? 146.083 89.377  108.877 1.00 39.43  ? 194 ALA A C   1 
ATOM   899   O O   . ALA A 1 194 ? 145.294 90.238  109.247 1.00 41.45  ? 194 ALA A O   1 
ATOM   900   C CB  . ALA A 1 194 ? 146.590 90.534  106.664 1.00 30.93  ? 194 ALA A CB  1 
ATOM   901   N N   . CYS A 1 195 ? 146.615 88.511  109.738 1.00 41.11  ? 195 CYS A N   1 
ATOM   902   C CA  . CYS A 1 195 ? 146.153 88.305  111.116 1.00 40.11  ? 195 CYS A CA  1 
ATOM   903   C C   . CYS A 1 195 ? 147.224 88.562  112.195 1.00 49.12  ? 195 CYS A C   1 
ATOM   904   O O   . CYS A 1 195 ? 146.912 88.518  113.387 1.00 51.56  ? 195 CYS A O   1 
ATOM   905   C CB  . CYS A 1 195 ? 145.585 86.882  111.213 1.00 43.03  ? 195 CYS A CB  1 
ATOM   906   S SG  . CYS A 1 195 ? 146.860 85.651  110.824 1.00 60.88  ? 195 CYS A SG  1 
ATOM   907   N N   . GLY A 1 196 ? 148.474 88.846  111.808 1.00 44.92  ? 196 GLY A N   1 
ATOM   908   C CA  . GLY A 1 196 ? 149.539 89.220  112.737 1.00 41.01  ? 196 GLY A CA  1 
ATOM   909   C C   . GLY A 1 196 ? 149.237 90.488  113.546 1.00 40.83  ? 196 GLY A C   1 
ATOM   910   O O   . GLY A 1 196 ? 148.317 91.243  113.243 1.00 44.42  ? 196 GLY A O   1 
ATOM   911   N N   . ARG A 1 197 ? 150.017 90.746  114.601 1.00 40.01  ? 197 ARG A N   1 
ATOM   912   C CA  . ARG A 1 197 ? 149.750 91.807  115.581 1.00 42.34  ? 197 ARG A CA  1 
ATOM   913   C C   . ARG A 1 197 ? 149.623 93.212  114.984 1.00 41.54  ? 197 ARG A C   1 
ATOM   914   O O   . ARG A 1 197 ? 148.902 94.029  115.541 1.00 42.13  ? 197 ARG A O   1 
ATOM   915   C CB  . ARG A 1 197 ? 150.829 91.744  116.679 1.00 42.99  ? 197 ARG A CB  1 
ATOM   916   C CG  . ARG A 1 197 ? 150.562 92.622  117.909 1.00 41.25  ? 197 ARG A CG  1 
ATOM   917   C CD  . ARG A 1 197 ? 149.215 92.290  118.552 1.00 41.36  ? 197 ARG A CD  1 
ATOM   918   N NE  . ARG A 1 197 ? 148.992 93.030  119.799 1.00 49.80  ? 197 ARG A NE  1 
ATOM   919   C CZ  . ARG A 1 197 ? 147.863 93.065  120.478 1.00 51.78  ? 197 ARG A CZ  1 
ATOM   920   N NH1 . ARG A 1 197 ? 147.781 93.765  121.567 1.00 46.12  ? 197 ARG A NH1 1 
ATOM   921   N NH2 . ARG A 1 197 ? 146.802 92.412  120.098 1.00 48.39  ? 197 ARG A NH2 1 
ATOM   922   N N   . PHE A 1 198 ? 150.246 93.511  113.847 1.00 36.53  ? 198 PHE A N   1 
ATOM   923   C CA  . PHE A 1 198 ? 150.059 94.788  113.152 1.00 34.34  ? 198 PHE A CA  1 
ATOM   924   C C   . PHE A 1 198 ? 148.637 94.973  112.592 1.00 36.80  ? 198 PHE A C   1 
ATOM   925   O O   . PHE A 1 198 ? 148.146 96.089  112.476 1.00 31.80  ? 198 PHE A O   1 
ATOM   926   C CB  . PHE A 1 198 ? 151.083 94.880  112.018 1.00 29.26  ? 198 PHE A CB  1 
ATOM   927   C CG  . PHE A 1 198 ? 150.949 96.156  111.222 1.00 32.98  ? 198 PHE A CG  1 
ATOM   928   C CD1 . PHE A 1 198 ? 151.275 97.383  111.812 1.00 31.96  ? 198 PHE A CD1 1 
ATOM   929   C CD2 . PHE A 1 198 ? 150.404 96.121  109.930 1.00 31.66  ? 198 PHE A CD2 1 
ATOM   930   C CE1 . PHE A 1 198 ? 151.040 98.575  111.119 1.00 25.65  ? 198 PHE A CE1 1 
ATOM   931   C CE2 . PHE A 1 198 ? 150.178 97.316  109.229 1.00 28.53  ? 198 PHE A CE2 1 
ATOM   932   C CZ  . PHE A 1 198 ? 150.495 98.540  109.819 1.00 31.14  ? 198 PHE A CZ  1 
ATOM   933   N N   . PHE A 1 199 ? 147.957 93.884  112.249 1.00 39.37  ? 199 PHE A N   1 
ATOM   934   C CA  . PHE A 1 199 ? 146.631 93.904  111.640 1.00 28.27  ? 199 PHE A CA  1 
ATOM   935   C C   . PHE A 1 199 ? 145.483 93.770  112.642 1.00 34.31  ? 199 PHE A C   1 
ATOM   936   O O   . PHE A 1 199 ? 144.322 93.868  112.261 1.00 38.75  ? 199 PHE A O   1 
ATOM   937   C CB  . PHE A 1 199 ? 146.583 92.789  110.604 1.00 24.88  ? 199 PHE A CB  1 
ATOM   938   C CG  . PHE A 1 199 ? 147.656 92.916  109.559 1.00 30.56  ? 199 PHE A CG  1 
ATOM   939   C CD1 . PHE A 1 199 ? 147.613 93.981  108.649 1.00 31.32  ? 199 PHE A CD1 1 
ATOM   940   C CD2 . PHE A 1 199 ? 148.704 91.984  109.500 1.00 32.22  ? 199 PHE A CD2 1 
ATOM   941   C CE1 . PHE A 1 199 ? 148.594 94.096  107.651 1.00 31.58  ? 199 PHE A CE1 1 
ATOM   942   C CE2 . PHE A 1 199 ? 149.678 92.105  108.504 1.00 30.84  ? 199 PHE A CE2 1 
ATOM   943   C CZ  . PHE A 1 199 ? 149.625 93.154  107.581 1.00 29.86  ? 199 PHE A CZ  1 
ATOM   944   N N   . GLN A 1 200 ? 145.779 93.531  113.914 1.00 38.32  ? 200 GLN A N   1 
ATOM   945   C CA  . GLN A 1 200 ? 144.808 93.479  115.002 1.00 33.63  ? 200 GLN A CA  1 
ATOM   946   C C   . GLN A 1 200 ? 144.472 94.889  115.501 1.00 38.74  ? 200 GLN A C   1 
ATOM   947   O O   . GLN A 1 200 ? 145.274 95.807  115.375 1.00 40.13  ? 200 GLN A O   1 
ATOM   948   C CB  . GLN A 1 200 ? 145.363 92.600  116.131 1.00 36.97  ? 200 GLN A CB  1 
ATOM   949   C CG  . GLN A 1 200 ? 145.532 91.135  115.696 1.00 37.38  ? 200 GLN A CG  1 
ATOM   950   C CD  . GLN A 1 200 ? 146.324 90.292  116.687 1.00 41.48  ? 200 GLN A CD  1 
ATOM   951   O OE1 . GLN A 1 200 ? 146.511 90.636  117.847 1.00 44.86  ? 200 GLN A OE1 1 
ATOM   952   N NE2 . GLN A 1 200 ? 146.851 89.168  116.260 1.00 38.94  ? 200 GLN A NE2 1 
ATOM   953   N N   . LYS A 1 201 ? 143.300 95.084  116.111 1.00 42.97  ? 201 LYS A N   1 
ATOM   954   C CA  . LYS A 1 201 ? 142.933 96.348  116.760 1.00 40.51  ? 201 LYS A CA  1 
ATOM   955   C C   . LYS A 1 201 ? 143.473 96.374  118.196 1.00 46.35  ? 201 LYS A C   1 
ATOM   956   O O   . LYS A 1 201 ? 143.137 95.512  119.001 1.00 50.81  ? 201 LYS A O   1 
ATOM   957   C CB  . LYS A 1 201 ? 141.409 96.519  116.677 1.00 45.47  ? 201 LYS A CB  1 
ATOM   958   C CG  . LYS A 1 201 ? 140.871 97.846  117.224 1.00 47.23  ? 201 LYS A CG  1 
ATOM   959   C CD  . LYS A 1 201 ? 141.410 99.086  116.509 1.00 50.49  ? 201 LYS A CD  1 
ATOM   960   C CE  . LYS A 1 201 ? 140.721 100.332 117.065 1.00 52.40  ? 201 LYS A CE  1 
ATOM   961   N NZ  . LYS A 1 201 ? 141.231 101.573 116.454 1.00 51.61  ? 201 LYS A NZ  1 
ATOM   962   N N   . HIS A 1 202 ? 144.311 97.356  118.521 1.00 42.54  ? 202 HIS A N   1 
ATOM   963   C CA  . HIS A 1 202 ? 144.869 97.617  119.854 1.00 42.16  ? 202 HIS A CA  1 
ATOM   964   C C   . HIS A 1 202 ? 145.355 99.065  119.946 1.00 46.50  ? 202 HIS A C   1 
ATOM   965   O O   . HIS A 1 202 ? 145.307 99.803  118.962 1.00 48.39  ? 202 HIS A O   1 
ATOM   966   C CB  . HIS A 1 202 ? 145.997 96.621  120.159 1.00 42.71  ? 202 HIS A CB  1 
ATOM   967   C CG  . HIS A 1 202 ? 147.044 96.556  119.098 1.00 45.17  ? 202 HIS A CG  1 
ATOM   968   N ND1 . HIS A 1 202 ? 148.061 97.487  119.006 1.00 47.80  ? 202 HIS A ND1 1 
ATOM   969   C CD2 . HIS A 1 202 ? 147.239 95.681  118.089 1.00 44.55  ? 202 HIS A CD2 1 
ATOM   970   C CE1 . HIS A 1 202 ? 148.836 97.188  117.984 1.00 43.22  ? 202 HIS A CE1 1 
ATOM   971   N NE2 . HIS A 1 202 ? 148.353 96.082  117.405 1.00 39.99  ? 202 HIS A NE2 1 
ATOM   972   N N   . GLN A 1 203 ? 145.802 99.498  121.133 1.00 57.48  ? 203 GLN A N   1 
ATOM   973   C CA  . GLN A 1 203 ? 146.179 100.932 121.347 1.00 57.27  ? 203 GLN A CA  1 
ATOM   974   C C   . GLN A 1 203 ? 147.535 101.262 120.706 1.00 56.93  ? 203 GLN A C   1 
ATOM   975   O O   . GLN A 1 203 ? 147.813 102.463 120.526 1.00 56.55  ? 203 GLN A O   1 
ATOM   976   C CB  . GLN A 1 203 ? 146.151 101.230 122.851 1.00 54.65  ? 203 GLN A CB  1 
ATOM   977   C CG  . GLN A 1 203 ? 144.732 101.172 123.440 1.00 55.07  ? 203 GLN A CG  1 
ATOM   978   C CD  . GLN A 1 203 ? 144.716 101.485 124.916 1.00 60.45  ? 203 GLN A CD  1 
ATOM   979   O OE1 . GLN A 1 203 ? 143.673 101.457 125.566 1.00 61.84  ? 203 GLN A OE1 1 
ATOM   980   N NE2 . GLN A 1 203 ? 145.884 101.785 125.460 1.00 58.07  ? 203 GLN A NE2 1 
ATOM   981   N N   . GLY A 1 204 ? 148.339 100.252 120.375 1.00 49.41  ? 204 GLY A N   1 
ATOM   982   C CA  . GLY A 1 204 ? 149.653 100.408 119.756 1.00 46.63  ? 204 GLY A CA  1 
ATOM   983   C C   . GLY A 1 204 ? 149.620 100.703 118.257 1.00 45.77  ? 204 GLY A C   1 
ATOM   984   O O   . GLY A 1 204 ? 148.621 101.156 117.701 1.00 52.01  ? 204 GLY A O   1 
ATOM   985   N N   . THR A 1 205 ? 150.742 100.474 117.584 1.00 45.69  ? 205 THR A N   1 
ATOM   986   C CA  . THR A 1 205 ? 150.903 100.737 116.148 1.00 46.05  ? 205 THR A CA  1 
ATOM   987   C C   . THR A 1 205 ? 150.299 99.599  115.320 1.00 42.92  ? 205 THR A C   1 
ATOM   988   O O   . THR A 1 205 ? 150.831 98.491  115.261 1.00 43.37  ? 205 THR A O   1 
ATOM   989   C CB  . THR A 1 205 ? 152.376 101.046 115.805 1.00 46.43  ? 205 THR A CB  1 
ATOM   990   O OG1 . THR A 1 205 ? 153.260 100.085 116.331 1.00 53.17  ? 205 THR A OG1 1 
ATOM   991   C CG2 . THR A 1 205 ? 152.778 102.383 116.406 1.00 45.87  ? 205 THR A CG2 1 
ATOM   992   N N   . CYS A 1 206 ? 149.145 99.854  114.701 1.00 36.44  ? 206 CYS A N   1 
ATOM   993   C CA  . CYS A 1 206 ? 148.383 98.864  113.946 1.00 31.21  ? 206 CYS A CA  1 
ATOM   994   C C   . CYS A 1 206 ? 147.481 99.478  112.869 1.00 28.99  ? 206 CYS A C   1 
ATOM   995   O O   . CYS A 1 206 ? 147.164 100.667 112.881 1.00 33.97  ? 206 CYS A O   1 
ATOM   996   C CB  . CYS A 1 206 ? 147.567 98.002  114.918 1.00 34.69  ? 206 CYS A CB  1 
ATOM   997   S SG  . CYS A 1 206 ? 146.136 98.858  115.618 1.00 30.25  ? 206 CYS A SG  1 
ATOM   998   N N   . PHE A 1 207 ? 147.022 98.629  111.958 1.00 26.59  ? 207 PHE A N   1 
ATOM   999   C CA  . PHE A 1 207 ? 146.036 98.927  110.929 1.00 22.30  ? 207 PHE A CA  1 
ATOM   1000  C C   . PHE A 1 207 ? 145.036 97.771  110.850 1.00 22.78  ? 207 PHE A C   1 
ATOM   1001  O O   . PHE A 1 207 ? 145.215 96.825  110.092 1.00 30.79  ? 207 PHE A O   1 
ATOM   1002  C CB  . PHE A 1 207 ? 146.772 99.189  109.608 1.00 24.89  ? 207 PHE A CB  1 
ATOM   1003  C CG  . PHE A 1 207 ? 145.929 99.432  108.370 1.00 23.88  ? 207 PHE A CG  1 
ATOM   1004  C CD1 . PHE A 1 207 ? 144.661 100.037 108.424 1.00 26.38  ? 207 PHE A CD1 1 
ATOM   1005  C CD2 . PHE A 1 207 ? 146.471 99.099  107.119 1.00 30.94  ? 207 PHE A CD2 1 
ATOM   1006  C CE1 . PHE A 1 207 ? 143.951 100.296 107.241 1.00 21.95  ? 207 PHE A CE1 1 
ATOM   1007  C CE2 . PHE A 1 207 ? 145.760 99.349  105.936 1.00 24.61  ? 207 PHE A CE2 1 
ATOM   1008  C CZ  . PHE A 1 207 ? 144.498 99.957  105.998 1.00 28.13  ? 207 PHE A CZ  1 
ATOM   1009  N N   . TYR A 1 208 ? 143.981 97.835  111.660 1.00 22.04  ? 208 TYR A N   1 
ATOM   1010  C CA  . TYR A 1 208 ? 142.829 96.951  111.518 1.00 28.34  ? 208 TYR A CA  1 
ATOM   1011  C C   . TYR A 1 208 ? 141.914 97.411  110.375 1.00 30.84  ? 208 TYR A C   1 
ATOM   1012  O O   . TYR A 1 208 ? 141.473 98.554  110.340 1.00 34.14  ? 208 TYR A O   1 
ATOM   1013  C CB  . TYR A 1 208 ? 142.068 96.840  112.847 1.00 24.31  ? 208 TYR A CB  1 
ATOM   1014  C CG  . TYR A 1 208 ? 140.903 95.877  112.776 1.00 24.46  ? 208 TYR A CG  1 
ATOM   1015  C CD1 . TYR A 1 208 ? 141.128 94.498  112.892 1.00 27.59  ? 208 TYR A CD1 1 
ATOM   1016  C CD2 . TYR A 1 208 ? 139.610 96.348  112.487 1.00 28.51  ? 208 TYR A CD2 1 
ATOM   1017  C CE1 . TYR A 1 208 ? 140.081 93.582  112.695 1.00 32.19  ? 208 TYR A CE1 1 
ATOM   1018  C CE2 . TYR A 1 208 ? 138.564 95.433  112.276 1.00 26.46  ? 208 TYR A CE2 1 
ATOM   1019  C CZ  . TYR A 1 208 ? 138.797 94.051  112.381 1.00 32.07  ? 208 TYR A CZ  1 
ATOM   1020  O OH  . TYR A 1 208 ? 137.792 93.178  112.137 1.00 37.95  ? 208 TYR A OH  1 
ATOM   1021  N N   . PHE A 1 209 ? 141.571 96.499  109.470 1.00 27.39  ? 209 PHE A N   1 
ATOM   1022  C CA  . PHE A 1 209 ? 140.676 96.714  108.329 1.00 29.65  ? 209 PHE A CA  1 
ATOM   1023  C C   . PHE A 1 209 ? 139.777 95.490  108.110 1.00 27.13  ? 209 PHE A C   1 
ATOM   1024  O O   . PHE A 1 209 ? 139.306 95.226  107.011 1.00 38.68  ? 209 PHE A O   1 
ATOM   1025  C CB  . PHE A 1 209 ? 141.516 97.028  107.077 1.00 25.78  ? 209 PHE A CB  1 
ATOM   1026  C CG  . PHE A 1 209 ? 142.602 96.013  106.738 1.00 23.16  ? 209 PHE A CG  1 
ATOM   1027  C CD1 . PHE A 1 209 ? 142.297 94.781  106.126 1.00 24.16  ? 209 PHE A CD1 1 
ATOM   1028  C CD2 . PHE A 1 209 ? 143.941 96.312  107.036 1.00 22.88  ? 209 PHE A CD2 1 
ATOM   1029  C CE1 . PHE A 1 209 ? 143.315 93.849  105.853 1.00 27.74  ? 209 PHE A CE1 1 
ATOM   1030  C CE2 . PHE A 1 209 ? 144.960 95.402  106.721 1.00 29.89  ? 209 PHE A CE2 1 
ATOM   1031  C CZ  . PHE A 1 209 ? 144.649 94.160  106.148 1.00 27.63  ? 209 PHE A CZ  1 
ATOM   1032  N N   . GLY A 1 210 ? 139.554 94.697  109.150 1.00 23.23  ? 210 GLY A N   1 
ATOM   1033  C CA  . GLY A 1 210 ? 139.295 93.279  108.968 1.00 27.90  ? 210 GLY A CA  1 
ATOM   1034  C C   . GLY A 1 210 ? 140.648 92.608  108.746 1.00 41.48  ? 210 GLY A C   1 
ATOM   1035  O O   . GLY A 1 210 ? 141.684 93.162  109.117 1.00 52.52  ? 210 GLY A O   1 
ATOM   1036  N N   . GLU A 1 211 ? 140.680 91.448  108.102 1.00 36.84  ? 211 GLU A N   1 
ATOM   1037  C CA  . GLU A 1 211 ? 141.953 90.781  107.782 1.00 31.99  ? 211 GLU A CA  1 
ATOM   1038  C C   . GLU A 1 211 ? 142.048 90.363  106.311 1.00 33.69  ? 211 GLU A C   1 
ATOM   1039  O O   . GLU A 1 211 ? 143.087 89.917  105.844 1.00 35.37  ? 211 GLU A O   1 
ATOM   1040  C CB  . GLU A 1 211 ? 142.137 89.578  108.715 1.00 32.02  ? 211 GLU A CB  1 
ATOM   1041  C CG  . GLU A 1 211 ? 142.190 90.000  110.191 1.00 30.49  ? 211 GLU A CG  1 
ATOM   1042  C CD  . GLU A 1 211 ? 142.301 88.813  111.151 1.00 40.22  ? 211 GLU A CD  1 
ATOM   1043  O OE1 . GLU A 1 211 ? 141.977 87.663  110.774 1.00 43.91  ? 211 GLU A OE1 1 
ATOM   1044  O OE2 . GLU A 1 211 ? 142.649 89.036  112.327 1.00 42.80  ? 211 GLU A OE2 1 
ATOM   1045  N N   . LEU A 1 212 ? 140.952 90.492  105.563 1.00 38.64  ? 212 LEU A N   1 
ATOM   1046  C CA  . LEU A 1 212 ? 140.958 89.922  104.185 1.00 33.70  ? 212 LEU A CA  1 
ATOM   1047  C C   . LEU A 1 212 ? 141.031 91.000  103.102 1.00 33.76  ? 212 LEU A C   1 
ATOM   1048  O O   . LEU A 1 212 ? 140.671 92.161  103.382 1.00 40.09  ? 212 LEU A O   1 
ATOM   1049  C CB  . LEU A 1 212 ? 139.703 89.056  104.012 1.00 38.55  ? 212 LEU A CB  1 
ATOM   1050  C CG  . LEU A 1 212 ? 139.621 87.833  104.923 1.00 41.52  ? 212 LEU A CG  1 
ATOM   1051  C CD1 . LEU A 1 212 ? 139.424 88.251  106.374 1.00 40.34  ? 212 LEU A CD1 1 
ATOM   1052  C CD2 . LEU A 1 212 ? 138.500 86.904  104.484 1.00 38.83  ? 212 LEU A CD2 1 
ATOM   1053  N N   . PRO A 1 213 ? 141.480 90.645  101.878 1.00 36.26  ? 213 PRO A N   1 
ATOM   1054  C CA  . PRO A 1 213 ? 141.534 91.594  100.765 1.00 37.61  ? 213 PRO A CA  1 
ATOM   1055  C C   . PRO A 1 213 ? 140.226 92.383  100.623 1.00 37.40  ? 213 PRO A C   1 
ATOM   1056  O O   . PRO A 1 213 ? 140.295 93.598  100.569 1.00 35.74  ? 213 PRO A O   1 
ATOM   1057  C CB  . PRO A 1 213 ? 141.718 90.673  99.551  1.00 40.37  ? 213 PRO A CB  1 
ATOM   1058  C CG  . PRO A 1 213 ? 142.507 89.506  100.099 1.00 32.93  ? 213 PRO A CG  1 
ATOM   1059  C CD  . PRO A 1 213 ? 141.980 89.319  101.506 1.00 33.68  ? 213 PRO A CD  1 
ATOM   1060  N N   . LEU A 1 214 ? 139.081 91.695  100.562 1.00 34.17  ? 214 LEU A N   1 
ATOM   1061  C CA  . LEU A 1 214 ? 137.841 92.441  100.333 1.00 32.87  ? 214 LEU A CA  1 
ATOM   1062  C C   . LEU A 1 214 ? 137.589 93.508  101.406 1.00 26.47  ? 214 LEU A C   1 
ATOM   1063  O O   . LEU A 1 214 ? 137.192 94.626  101.090 1.00 32.33  ? 214 LEU A O   1 
ATOM   1064  C CB  . LEU A 1 214 ? 136.665 91.458  100.229 1.00 38.33  ? 214 LEU A CB  1 
ATOM   1065  C CG  . LEU A 1 214 ? 135.316 92.146  99.957  1.00 33.63  ? 214 LEU A CG  1 
ATOM   1066  C CD1 . LEU A 1 214 ? 135.276 92.760  98.566  1.00 34.10  ? 214 LEU A CD1 1 
ATOM   1067  C CD2 . LEU A 1 214 ? 134.174 91.154  100.079 1.00 32.84  ? 214 LEU A CD2 1 
ATOM   1068  N N   . SER A 1 215 ? 137.847 93.184  102.670 1.00 20.77  ? 215 SER A N   1 
ATOM   1069  C CA  . SER A 1 215 ? 137.702 94.138  103.766 1.00 14.71  ? 215 SER A CA  1 
ATOM   1070  C C   . SER A 1 215 ? 138.729 95.260  103.685 1.00 22.18  ? 215 SER A C   1 
ATOM   1071  O O   . SER A 1 215 ? 138.366 96.412  103.884 1.00 23.95  ? 215 SER A O   1 
ATOM   1072  C CB  . SER A 1 215 ? 137.770 93.447  105.121 1.00 26.47  ? 215 SER A CB  1 
ATOM   1073  O OG  . SER A 1 215 ? 136.914 92.323  105.151 1.00 34.27  ? 215 SER A OG  1 
ATOM   1074  N N   . LEU A 1 216 ? 139.968 94.972  103.279 1.00 36.54  ? 216 LEU A N   1 
ATOM   1075  C CA  . LEU A 1 216 ? 140.958 95.987  102.937 1.00 23.43  ? 216 LEU A CA  1 
ATOM   1076  C C   . LEU A 1 216 ? 140.438 96.896  101.821 1.00 28.15  ? 216 LEU A C   1 
ATOM   1077  O O   . LEU A 1 216 ? 140.324 98.092  102.039 1.00 38.38  ? 216 LEU A O   1 
ATOM   1078  C CB  . LEU A 1 216 ? 142.282 95.299  102.578 1.00 26.52  ? 216 LEU A CB  1 
ATOM   1079  C CG  . LEU A 1 216 ? 143.444 96.249  102.246 1.00 27.29  ? 216 LEU A CG  1 
ATOM   1080  C CD1 . LEU A 1 216 ? 143.829 97.184  103.387 1.00 23.30  ? 216 LEU A CD1 1 
ATOM   1081  C CD2 . LEU A 1 216 ? 144.654 95.400  101.891 1.00 25.38  ? 216 LEU A CD2 1 
ATOM   1082  N N   . ALA A 1 217 ? 140.037 96.351  100.669 1.00 26.06  ? 217 ALA A N   1 
ATOM   1083  C CA  . ALA A 1 217 ? 139.539 97.142  99.546  1.00 22.88  ? 217 ALA A CA  1 
ATOM   1084  C C   . ALA A 1 217 ? 138.329 98.027  99.907  1.00 31.61  ? 217 ALA A C   1 
ATOM   1085  O O   . ALA A 1 217 ? 138.218 99.158  99.437  1.00 31.82  ? 217 ALA A O   1 
ATOM   1086  C CB  . ALA A 1 217 ? 139.207 96.185  98.398  1.00 26.51  ? 217 ALA A CB  1 
ATOM   1087  N N   . ALA A 1 218 ? 137.430 97.546  100.771 1.00 32.97  ? 218 ALA A N   1 
ATOM   1088  C CA  . ALA A 1 218 ? 136.326 98.331  101.303 1.00 24.68  ? 218 ALA A CA  1 
ATOM   1089  C C   . ALA A 1 218 ? 136.800 99.423  102.276 1.00 24.51  ? 218 ALA A C   1 
ATOM   1090  O O   . ALA A 1 218 ? 136.387 100.574 102.159 1.00 29.46  ? 218 ALA A O   1 
ATOM   1091  C CB  . ALA A 1 218 ? 135.336 97.380  101.966 1.00 27.04  ? 218 ALA A CB  1 
ATOM   1092  N N   . CYS A 1 219 ? 137.694 99.104  103.210 1.00 28.54  ? 219 CYS A N   1 
ATOM   1093  C CA  . CYS A 1 219 ? 138.190 100.060 104.200 1.00 28.74  ? 219 CYS A CA  1 
ATOM   1094  C C   . CYS A 1 219 ? 139.079 101.159 103.601 1.00 33.23  ? 219 CYS A C   1 
ATOM   1095  O O   . CYS A 1 219 ? 139.137 102.265 104.130 1.00 32.12  ? 219 CYS A O   1 
ATOM   1096  C CB  . CYS A 1 219 ? 138.907 99.321  105.339 1.00 32.38  ? 219 CYS A CB  1 
ATOM   1097  S SG  . CYS A 1 219 ? 137.784 98.212  106.259 1.00 36.50  ? 219 CYS A SG  1 
ATOM   1098  N N   . THR A 1 220 ? 139.629 100.883 102.411 1.00 40.44  ? 220 THR A N   1 
ATOM   1099  C CA  . THR A 1 220 ? 140.452 101.892 101.691 1.00 33.81  ? 220 THR A CA  1 
ATOM   1100  C C   . THR A 1 220 ? 139.580 102.659 100.686 1.00 38.69  ? 220 THR A C   1 
ATOM   1101  O O   . THR A 1 220 ? 140.099 103.640 100.122 1.00 48.03  ? 220 THR A O   1 
ATOM   1102  C CB  . THR A 1 220 ? 141.638 101.225 100.982 1.00 38.80  ? 220 THR A CB  1 
ATOM   1103  O OG1 . THR A 1 220 ? 141.111 100.278 100.052 1.00 43.27  ? 220 THR A OG1 1 
ATOM   1104  C CG2 . THR A 1 220 ? 142.582 100.532 101.940 1.00 37.39  ? 220 THR A CG2 1 
ATOM   1105  N N   . LYS A 1 221 ? 138.341 102.210 100.439 1.00 41.73  ? 221 LYS A N   1 
ATOM   1106  C CA  . LYS A 1 221 ? 137.375 102.924 99.541  1.00 40.12  ? 221 LYS A CA  1 
ATOM   1107  C C   . LYS A 1 221 ? 137.670 102.635 98.057  1.00 43.09  ? 221 LYS A C   1 
ATOM   1108  O O   . LYS A 1 221 ? 137.306 103.474 97.209  1.00 43.36  ? 221 LYS A O   1 
ATOM   1109  C CB  . LYS A 1 221 ? 137.314 104.420 99.882  1.00 37.84  ? 221 LYS A CB  1 
ATOM   1110  C CG  . LYS A 1 221 ? 138.153 105.362 99.027  1.00 44.63  ? 221 LYS A CG  1 
ATOM   1111  C CD  . LYS A 1 221 ? 137.927 106.820 99.358  1.00 45.46  ? 221 LYS A CD  1 
ATOM   1112  C CE  . LYS A 1 221 ? 138.460 107.759 98.297  1.00 49.55  ? 221 LYS A CE  1 
ATOM   1113  N NZ  . LYS A 1 221 ? 138.276 109.179 98.679  1.00 50.93  ? 221 LYS A NZ  1 
ATOM   1114  N N   . GLN A 1 222 ? 138.250 101.474 97.744  1.00 44.99  ? 222 GLN A N   1 
ATOM   1115  C CA  . GLN A 1 222 ? 138.528 101.086 96.360  1.00 43.83  ? 222 GLN A CA  1 
ATOM   1116  C C   . GLN A 1 222 ? 137.342 100.331 95.760  1.00 40.13  ? 222 GLN A C   1 
ATOM   1117  O O   . GLN A 1 222 ? 137.365 99.112  95.612  1.00 41.93  ? 222 GLN A O   1 
ATOM   1118  C CB  . GLN A 1 222 ? 139.824 100.277 96.295  1.00 45.16  ? 222 GLN A CB  1 
ATOM   1119  C CG  . GLN A 1 222 ? 141.020 101.184 96.579  1.00 38.59  ? 222 GLN A CG  1 
ATOM   1120  C CD  . GLN A 1 222 ? 142.246 100.394 96.976  1.00 40.34  ? 222 GLN A CD  1 
ATOM   1121  O OE1 . GLN A 1 222 ? 142.799 100.576 98.042  1.00 47.11  ? 222 GLN A OE1 1 
ATOM   1122  N NE2 . GLN A 1 222 ? 142.714 99.484  96.164  1.00 45.84  ? 222 GLN A NE2 1 
ATOM   1123  N N   . TRP A 1 223 ? 136.277 101.056 95.436  1.00 41.89  ? 223 TRP A N   1 
ATOM   1124  C CA  . TRP A 1 223 ? 135.018 100.460 94.989  1.00 50.21  ? 223 TRP A CA  1 
ATOM   1125  C C   . TRP A 1 223 ? 135.147 99.649  93.688  1.00 50.27  ? 223 TRP A C   1 
ATOM   1126  O O   . TRP A 1 223 ? 134.484 98.634  93.521  1.00 50.28  ? 223 TRP A O   1 
ATOM   1127  C CB  . TRP A 1 223 ? 133.977 101.579 94.881  1.00 47.55  ? 223 TRP A CB  1 
ATOM   1128  C CG  . TRP A 1 223 ? 132.595 101.101 94.590  1.00 48.26  ? 223 TRP A CG  1 
ATOM   1129  C CD1 . TRP A 1 223 ? 131.846 101.438 93.516  1.00 50.98  ? 223 TRP A CD1 1 
ATOM   1130  C CD2 . TRP A 1 223 ? 131.781 100.183 95.377  1.00 51.71  ? 223 TRP A CD2 1 
ATOM   1131  N NE1 . TRP A 1 223 ? 130.630 100.786 93.583  1.00 52.41  ? 223 TRP A NE1 1 
ATOM   1132  C CE2 . TRP A 1 223 ? 130.542 99.986  94.701  1.00 53.70  ? 223 TRP A CE2 1 
ATOM   1133  C CE3 . TRP A 1 223 ? 131.972 99.481  96.585  1.00 48.93  ? 223 TRP A CE3 1 
ATOM   1134  C CZ2 . TRP A 1 223 ? 129.557 99.123  95.188  1.00 48.71  ? 223 TRP A CZ2 1 
ATOM   1135  C CZ3 . TRP A 1 223 ? 131.000 98.590  97.071  1.00 44.18  ? 223 TRP A CZ3 1 
ATOM   1136  C CH2 . TRP A 1 223 ? 129.814 98.385  96.353  1.00 50.56  ? 223 TRP A CH2 1 
ATOM   1137  N N   . ASP A 1 224 ? 136.063 100.039 92.801  1.00 50.09  ? 224 ASP A N   1 
ATOM   1138  C CA  . ASP A 1 224 ? 136.416 99.290  91.552  1.00 49.31  ? 224 ASP A CA  1 
ATOM   1139  C C   . ASP A 1 224 ? 137.229 98.017  91.856  1.00 49.15  ? 224 ASP A C   1 
ATOM   1140  O O   . ASP A 1 224 ? 137.115 97.077  91.046  1.00 48.67  ? 224 ASP A O   1 
ATOM   1141  C CB  . ASP A 1 224 ? 137.179 100.184 90.571  1.00 51.64  ? 224 ASP A CB  1 
ATOM   1142  C CG  . ASP A 1 224 ? 138.514 100.666 91.114  1.00 56.26  ? 224 ASP A CG  1 
ATOM   1143  O OD1 . ASP A 1 224 ? 138.776 100.433 92.311  1.00 54.71  ? 224 ASP A OD1 1 
ATOM   1144  O OD2 . ASP A 1 224 ? 139.280 101.265 90.335  1.00 57.67  ? 224 ASP A OD2 1 
ATOM   1145  N N   . VAL A 1 225 ? 137.998 97.945  92.946  1.00 48.37  ? 225 VAL A N   1 
ATOM   1146  C CA  . VAL A 1 225 ? 138.616 96.695  93.407  1.00 45.62  ? 225 VAL A CA  1 
ATOM   1147  C C   . VAL A 1 225 ? 137.588 95.801  94.101  1.00 48.98  ? 225 VAL A C   1 
ATOM   1148  O O   . VAL A 1 225 ? 137.588 94.596  93.876  1.00 48.56  ? 225 VAL A O   1 
ATOM   1149  C CB  . VAL A 1 225 ? 139.822 96.965  94.325  1.00 46.89  ? 225 VAL A CB  1 
ATOM   1150  C CG1 . VAL A 1 225 ? 140.415 95.676  94.888  1.00 46.82  ? 225 VAL A CG1 1 
ATOM   1151  C CG2 . VAL A 1 225 ? 140.945 97.683  93.573  1.00 45.09  ? 225 VAL A CG2 1 
ATOM   1152  N N   . VAL A 1 226 ? 136.682 96.370  94.901  1.00 47.35  ? 226 VAL A N   1 
ATOM   1153  C CA  . VAL A 1 226 ? 135.590 95.637  95.554  1.00 46.28  ? 226 VAL A CA  1 
ATOM   1154  C C   . VAL A 1 226 ? 134.715 94.908  94.532  1.00 45.28  ? 226 VAL A C   1 
ATOM   1155  O O   . VAL A 1 226 ? 134.542 93.696  94.639  1.00 46.38  ? 226 VAL A O   1 
ATOM   1156  C CB  . VAL A 1 226 ? 134.760 96.586  96.440  1.00 44.68  ? 226 VAL A CB  1 
ATOM   1157  C CG1 . VAL A 1 226 ? 133.435 95.986  96.902  1.00 47.51  ? 226 VAL A CG1 1 
ATOM   1158  C CG2 . VAL A 1 226 ? 135.540 96.990  97.688  1.00 41.76  ? 226 VAL A CG2 1 
ATOM   1159  N N   . THR A 1 227 ? 134.208 95.609  93.512  1.00 51.29  ? 227 THR A N   1 
ATOM   1160  C CA  . THR A 1 227 ? 133.396 94.961  92.474  1.00 51.12  ? 227 THR A CA  1 
ATOM   1161  C C   . THR A 1 227 ? 134.190 93.928  91.685  1.00 50.49  ? 227 THR A C   1 
ATOM   1162  O O   . THR A 1 227 ? 133.661 92.860  91.410  1.00 54.87  ? 227 THR A O   1 
ATOM   1163  C CB  . THR A 1 227 ? 132.742 95.960  91.514  1.00 53.14  ? 227 THR A CB  1 
ATOM   1164  O OG1 . THR A 1 227 ? 133.708 96.755  90.884  1.00 55.88  ? 227 THR A OG1 1 
ATOM   1165  C CG2 . THR A 1 227 ? 131.756 96.865  92.236  1.00 51.72  ? 227 THR A CG2 1 
ATOM   1166  N N   . TYR A 1 228 ? 135.467 94.159  91.376  1.00 48.60  ? 228 TYR A N   1 
ATOM   1167  C CA  . TYR A 1 228 ? 136.310 93.139  90.757  1.00 46.01  ? 228 TYR A CA  1 
ATOM   1168  C C   . TYR A 1 228 ? 136.487 91.900  91.644  1.00 46.16  ? 228 TYR A C   1 
ATOM   1169  O O   . TYR A 1 228 ? 136.237 90.778  91.203  1.00 49.22  ? 228 TYR A O   1 
ATOM   1170  C CB  . TYR A 1 228 ? 137.698 93.656  90.375  1.00 50.00  ? 228 TYR A CB  1 
ATOM   1171  C CG  . TYR A 1 228 ? 138.594 92.550  89.882  1.00 54.69  ? 228 TYR A CG  1 
ATOM   1172  C CD1 . TYR A 1 228 ? 138.530 92.102  88.573  1.00 52.37  ? 228 TYR A CD1 1 
ATOM   1173  C CD2 . TYR A 1 228 ? 139.457 91.897  90.745  1.00 50.90  ? 228 TYR A CD2 1 
ATOM   1174  C CE1 . TYR A 1 228 ? 139.323 91.058  88.127  1.00 48.91  ? 228 TYR A CE1 1 
ATOM   1175  C CE2 . TYR A 1 228 ? 140.258 90.854  90.317  1.00 45.62  ? 228 TYR A CE2 1 
ATOM   1176  C CZ  . TYR A 1 228 ? 140.190 90.432  89.004  1.00 51.33  ? 228 TYR A CZ  1 
ATOM   1177  O OH  . TYR A 1 228 ? 140.975 89.403  88.581  1.00 56.03  ? 228 TYR A OH  1 
ATOM   1178  N N   . LEU A 1 229 ? 136.873 92.062  92.909  1.00 50.38  ? 229 LEU A N   1 
ATOM   1179  C CA  . LEU A 1 229 ? 137.051 90.938  93.827  1.00 49.19  ? 229 LEU A CA  1 
ATOM   1180  C C   . LEU A 1 229 ? 135.756 90.141  93.999  1.00 54.21  ? 229 LEU A C   1 
ATOM   1181  O O   . LEU A 1 229 ? 135.820 88.923  94.071  1.00 54.88  ? 229 LEU A O   1 
ATOM   1182  C CB  . LEU A 1 229 ? 137.556 91.426  95.193  1.00 48.81  ? 229 LEU A CB  1 
ATOM   1183  C CG  . LEU A 1 229 ? 139.006 91.938  95.234  1.00 52.30  ? 229 LEU A CG  1 
ATOM   1184  C CD1 . LEU A 1 229 ? 139.333 92.353  96.665  1.00 46.38  ? 229 LEU A CD1 1 
ATOM   1185  C CD2 . LEU A 1 229 ? 140.032 90.897  94.785  1.00 51.42  ? 229 LEU A CD2 1 
ATOM   1186  N N   . LEU A 1 230 ? 134.598 90.798  94.029  1.00 52.98  ? 230 LEU A N   1 
ATOM   1187  C CA  . LEU A 1 230 ? 133.290 90.155  94.114  1.00 50.07  ? 230 LEU A CA  1 
ATOM   1188  C C   . LEU A 1 230 ? 132.846 89.472  92.807  1.00 53.51  ? 230 LEU A C   1 
ATOM   1189  O O   . LEU A 1 230 ? 132.348 88.350  92.848  1.00 56.90  ? 230 LEU A O   1 
ATOM   1190  C CB  . LEU A 1 230 ? 132.268 91.217  94.545  1.00 51.46  ? 230 LEU A CB  1 
ATOM   1191  C CG  . LEU A 1 230 ? 132.385 91.678  96.008  1.00 46.94  ? 230 LEU A CG  1 
ATOM   1192  C CD1 . LEU A 1 230 ? 131.469 92.871  96.260  1.00 46.96  ? 230 LEU A CD1 1 
ATOM   1193  C CD2 . LEU A 1 230 ? 131.991 90.579  96.982  1.00 45.33  ? 230 LEU A CD2 1 
ATOM   1194  N N   . GLU A 1 231 ? 132.991 90.125  91.656  1.00 59.08  ? 231 GLU A N   1 
ATOM   1195  C CA  . GLU A 1 231 ? 132.365 89.710  90.392  1.00 57.35  ? 231 GLU A CA  1 
ATOM   1196  C C   . GLU A 1 231 ? 133.283 88.964  89.407  1.00 60.43  ? 231 GLU A C   1 
ATOM   1197  O O   . GLU A 1 231 ? 132.788 88.473  88.389  1.00 66.58  ? 231 GLU A O   1 
ATOM   1198  C CB  . GLU A 1 231 ? 131.723 90.927  89.708  1.00 58.53  ? 231 GLU A CB  1 
ATOM   1199  C CG  . GLU A 1 231 ? 130.634 91.575  90.572  1.00 60.62  ? 231 GLU A CG  1 
ATOM   1200  C CD  . GLU A 1 231 ? 129.821 92.611  89.792  1.00 61.83  ? 231 GLU A CD  1 
ATOM   1201  O OE1 . GLU A 1 231 ? 130.413 93.496  89.136  1.00 62.92  ? 231 GLU A OE1 1 
ATOM   1202  O OE2 . GLU A 1 231 ? 128.572 92.546  89.836  1.00 63.22  ? 231 GLU A OE2 1 
ATOM   1203  N N   . ASN A 1 232 ? 134.594 88.863  89.650  1.00 57.16  ? 232 ASN A N   1 
ATOM   1204  C CA  . ASN A 1 232 ? 135.503 88.161  88.738  1.00 59.33  ? 232 ASN A CA  1 
ATOM   1205  C C   . ASN A 1 232 ? 135.193 86.646  88.627  1.00 60.58  ? 232 ASN A C   1 
ATOM   1206  O O   . ASN A 1 232 ? 134.672 86.051  89.574  1.00 60.33  ? 232 ASN A O   1 
ATOM   1207  C CB  . ASN A 1 232 ? 136.969 88.408  89.137  1.00 58.36  ? 232 ASN A CB  1 
ATOM   1208  C CG  . ASN A 1 232 ? 137.431 87.540  90.289  1.00 59.93  ? 232 ASN A CG  1 
ATOM   1209  O OD1 . ASN A 1 232 ? 137.867 86.418  90.096  1.00 60.95  ? 232 ASN A OD1 1 
ATOM   1210  N ND2 . ASN A 1 232 ? 137.341 88.015  91.502  1.00 54.49  ? 232 ASN A ND2 1 
ATOM   1211  N N   . PRO A 1 233 ? 135.537 85.992  87.501  1.00 62.00  ? 233 PRO A N   1 
ATOM   1212  C CA  . PRO A 1 233 ? 135.267 84.570  87.292  1.00 61.49  ? 233 PRO A CA  1 
ATOM   1213  C C   . PRO A 1 233 ? 136.303 83.617  87.921  1.00 63.66  ? 233 PRO A C   1 
ATOM   1214  O O   . PRO A 1 233 ? 136.014 82.434  88.085  1.00 63.41  ? 233 PRO A O   1 
ATOM   1215  C CB  . PRO A 1 233 ? 135.239 84.413  85.774  1.00 60.40  ? 233 PRO A CB  1 
ATOM   1216  C CG  . PRO A 1 233 ? 136.254 85.445  85.294  1.00 61.39  ? 233 PRO A CG  1 
ATOM   1217  C CD  . PRO A 1 233 ? 136.053 86.592  86.279  1.00 59.44  ? 233 PRO A CD  1 
ATOM   1218  N N   . HIS A 1 234 ? 137.513 84.081  88.236  1.00 64.62  ? 234 HIS A N   1 
ATOM   1219  C CA  . HIS A 1 234 ? 138.651 83.234  88.632  1.00 64.80  ? 234 HIS A CA  1 
ATOM   1220  C C   . HIS A 1 234 ? 138.529 82.736  90.073  1.00 63.52  ? 234 HIS A C   1 
ATOM   1221  O O   . HIS A 1 234 ? 138.646 81.516  90.292  1.00 63.23  ? 234 HIS A O   1 
ATOM   1222  C CB  . HIS A 1 234 ? 139.963 84.007  88.435  1.00 63.55  ? 234 HIS A CB  1 
ATOM   1223  C CG  . HIS A 1 234 ? 139.823 85.198  87.548  1.00 65.40  ? 234 HIS A CG  1 
ATOM   1224  N ND1 . HIS A 1 234 ? 139.716 85.088  86.176  1.00 65.39  ? 234 HIS A ND1 1 
ATOM   1225  C CD2 . HIS A 1 234 ? 139.771 86.518  87.827  1.00 65.37  ? 234 HIS A CD2 1 
ATOM   1226  C CE1 . HIS A 1 234 ? 139.606 86.290  85.648  1.00 65.63  ? 234 HIS A CE1 1 
ATOM   1227  N NE2 . HIS A 1 234 ? 139.634 87.185  86.641  1.00 65.51  ? 234 HIS A NE2 1 
ATOM   1228  N N   . GLN A 1 235 ? 138.292 83.659  91.002  1.00 64.12  ? 235 GLN A N   1 
ATOM   1229  C CA  . GLN A 1 235 ? 137.885 83.377  92.375  1.00 62.88  ? 235 GLN A CA  1 
ATOM   1230  C C   . GLN A 1 235 ? 137.140 84.602  92.923  1.00 63.19  ? 235 GLN A C   1 
ATOM   1231  O O   . GLN A 1 235 ? 137.776 85.624  93.200  1.00 60.94  ? 235 GLN A O   1 
ATOM   1232  C CB  . GLN A 1 235 ? 139.093 83.009  93.256  1.00 59.15  ? 235 GLN A CB  1 
ATOM   1233  C CG  . GLN A 1 235 ? 138.643 82.689  94.690  1.00 61.24  ? 235 GLN A CG  1 
ATOM   1234  C CD  . GLN A 1 235 ? 139.772 82.245  95.615  1.00 64.73  ? 235 GLN A CD  1 
ATOM   1235  O OE1 . GLN A 1 235 ? 140.743 81.622  95.219  1.00 64.60  ? 235 GLN A OE1 1 
ATOM   1236  N NE2 . GLN A 1 235 ? 139.673 82.553  96.891  1.00 64.37  ? 235 GLN A NE2 1 
ATOM   1237  N N   . PRO A 1 236 ? 135.812 84.536  93.109  1.00 64.19  ? 236 PRO A N   1 
ATOM   1238  C CA  . PRO A 1 236 ? 135.067 85.622  93.725  1.00 58.92  ? 236 PRO A CA  1 
ATOM   1239  C C   . PRO A 1 236 ? 135.277 85.649  95.244  1.00 57.63  ? 236 PRO A C   1 
ATOM   1240  O O   . PRO A 1 236 ? 135.270 84.612  95.910  1.00 57.68  ? 236 PRO A O   1 
ATOM   1241  C CB  . PRO A 1 236 ? 133.612 85.370  93.333  1.00 57.66  ? 236 PRO A CB  1 
ATOM   1242  C CG  . PRO A 1 236 ? 133.537 83.851  93.214  1.00 59.47  ? 236 PRO A CG  1 
ATOM   1243  C CD  . PRO A 1 236 ? 134.919 83.465  92.697  1.00 58.85  ? 236 PRO A CD  1 
ATOM   1244  N N   . ALA A 1 237 ? 135.416 86.840  95.813  1.00 53.18  ? 237 ALA A N   1 
ATOM   1245  C CA  . ALA A 1 237 ? 135.263 87.083  97.238  1.00 52.62  ? 237 ALA A CA  1 
ATOM   1246  C C   . ALA A 1 237 ? 133.803 86.848  97.663  1.00 54.60  ? 237 ALA A C   1 
ATOM   1247  O O   . ALA A 1 237 ? 132.874 87.100  96.894  1.00 56.16  ? 237 ALA A O   1 
ATOM   1248  C CB  . ALA A 1 237 ? 135.692 88.513  97.558  1.00 51.41  ? 237 ALA A CB  1 
ATOM   1249  N N   . SER A 1 238 ? 133.587 86.407  98.899  1.00 44.30  ? 238 SER A N   1 
ATOM   1250  C CA  . SER A 1 238 ? 132.257 86.321  99.492  1.00 46.74  ? 238 SER A CA  1 
ATOM   1251  C C   . SER A 1 238 ? 132.093 87.402  100.555 1.00 46.04  ? 238 SER A C   1 
ATOM   1252  O O   . SER A 1 238 ? 132.957 87.602  101.405 1.00 49.21  ? 238 SER A O   1 
ATOM   1253  C CB  . SER A 1 238 ? 131.950 84.912  100.004 1.00 48.04  ? 238 SER A CB  1 
ATOM   1254  O OG  . SER A 1 238 ? 132.851 84.488  100.999 1.00 48.60  ? 238 SER A OG  1 
ATOM   1255  N N   . LEU A 1 239 ? 130.952 88.090  100.526 1.00 42.88  ? 239 LEU A N   1 
ATOM   1256  C CA  . LEU A 1 239 ? 130.577 89.074  101.546 1.00 42.11  ? 239 LEU A CA  1 
ATOM   1257  C C   . LEU A 1 239 ? 130.387 88.415  102.922 1.00 43.31  ? 239 LEU A C   1 
ATOM   1258  O O   . LEU A 1 239 ? 130.511 89.069  103.952 1.00 44.60  ? 239 LEU A O   1 
ATOM   1259  C CB  . LEU A 1 239 ? 129.297 89.789  101.081 1.00 38.98  ? 239 LEU A CB  1 
ATOM   1260  C CG  . LEU A 1 239 ? 129.526 90.664  99.839  1.00 42.76  ? 239 LEU A CG  1 
ATOM   1261  C CD1 . LEU A 1 239 ? 128.237 90.942  99.095  1.00 43.81  ? 239 LEU A CD1 1 
ATOM   1262  C CD2 . LEU A 1 239 ? 130.139 91.999  100.218 1.00 41.72  ? 239 LEU A CD2 1 
ATOM   1263  N N   . GLU A 1 240 ? 130.134 87.108  102.933 1.00 44.40  ? 240 GLU A N   1 
ATOM   1264  C CA  . GLU A 1 240 ? 130.006 86.262  104.116 1.00 42.92  ? 240 GLU A CA  1 
ATOM   1265  C C   . GLU A 1 240 ? 131.331 85.950  104.818 1.00 44.65  ? 240 GLU A C   1 
ATOM   1266  O O   . GLU A 1 240 ? 131.304 85.472  105.948 1.00 50.87  ? 240 GLU A O   1 
ATOM   1267  C CB  . GLU A 1 240 ? 129.407 84.910  103.711 1.00 45.86  ? 240 GLU A CB  1 
ATOM   1268  C CG  . GLU A 1 240 ? 128.072 84.979  102.975 1.00 46.07  ? 240 GLU A CG  1 
ATOM   1269  C CD  . GLU A 1 240 ? 127.556 83.559  102.716 1.00 52.24  ? 240 GLU A CD  1 
ATOM   1270  O OE1 . GLU A 1 240 ? 127.233 82.842  103.687 1.00 50.19  ? 240 GLU A OE1 1 
ATOM   1271  O OE2 . GLU A 1 240 ? 127.516 83.139  101.538 1.00 54.52  ? 240 GLU A OE2 1 
ATOM   1272  N N   . ALA A 1 241 ? 132.482 86.135  104.169 1.00 42.09  ? 241 ALA A N   1 
ATOM   1273  C CA  . ALA A 1 241 ? 133.771 85.724  104.722 1.00 39.61  ? 241 ALA A CA  1 
ATOM   1274  C C   . ALA A 1 241 ? 134.146 86.527  105.977 1.00 36.97  ? 241 ALA A C   1 
ATOM   1275  O O   . ALA A 1 241 ? 133.955 87.741  106.036 1.00 39.55  ? 241 ALA A O   1 
ATOM   1276  C CB  . ALA A 1 241 ? 134.847 85.832  103.643 1.00 41.33  ? 241 ALA A CB  1 
ATOM   1277  N N   . THR A 1 242 ? 134.713 85.850  106.974 1.00 37.09  ? 242 THR A N   1 
ATOM   1278  C CA  . THR A 1 242 ? 135.011 86.419  108.298 1.00 38.69  ? 242 THR A CA  1 
ATOM   1279  C C   . THR A 1 242 ? 136.487 86.341  108.676 1.00 36.50  ? 242 THR A C   1 
ATOM   1280  O O   . THR A 1 242 ? 137.215 85.434  108.266 1.00 41.05  ? 242 THR A O   1 
ATOM   1281  C CB  . THR A 1 242 ? 134.163 85.785  109.409 1.00 39.06  ? 242 THR A CB  1 
ATOM   1282  O OG1 . THR A 1 242 ? 134.346 84.393  109.452 1.00 44.88  ? 242 THR A OG1 1 
ATOM   1283  C CG2 . THR A 1 242 ? 132.676 86.066  109.257 1.00 34.83  ? 242 THR A CG2 1 
ATOM   1284  N N   . ASP A 1 243 ? 136.938 87.318  109.463 1.00 34.90  ? 243 ASP A N   1 
ATOM   1285  C CA  . ASP A 1 243 ? 138.337 87.303  109.979 1.00 31.94  ? 243 ASP A CA  1 
ATOM   1286  C C   . ASP A 1 243 ? 138.455 86.575  111.332 1.00 37.80  ? 243 ASP A C   1 
ATOM   1287  O O   . ASP A 1 243 ? 137.470 85.929  111.740 1.00 46.01  ? 243 ASP A O   1 
ATOM   1288  C CB  . ASP A 1 243 ? 138.888 88.726  110.102 1.00 33.87  ? 243 ASP A CB  1 
ATOM   1289  C CG  . ASP A 1 243 ? 138.235 89.532  111.212 1.00 38.18  ? 243 ASP A CG  1 
ATOM   1290  O OD1 . ASP A 1 243 ? 137.367 88.969  111.909 1.00 42.62  ? 243 ASP A OD1 1 
ATOM   1291  O OD2 . ASP A 1 243 ? 138.602 90.712  111.371 1.00 42.72  ? 243 ASP A OD2 1 
ATOM   1292  N N   . SER A 1 244 ? 139.610 86.683  111.994 1.00 40.28  ? 244 SER A N   1 
ATOM   1293  C CA  . SER A 1 244 ? 139.906 85.991  113.258 1.00 40.03  ? 244 SER A CA  1 
ATOM   1294  C C   . SER A 1 244 ? 139.054 86.424  114.463 1.00 42.75  ? 244 SER A C   1 
ATOM   1295  O O   . SER A 1 244 ? 139.058 85.729  115.475 1.00 47.88  ? 244 SER A O   1 
ATOM   1296  C CB  . SER A 1 244 ? 141.380 86.173  113.622 1.00 44.79  ? 244 SER A CB  1 
ATOM   1297  O OG  . SER A 1 244 ? 142.223 85.794  112.553 1.00 49.99  ? 244 SER A OG  1 
ATOM   1298  N N   . LEU A 1 245 ? 138.330 87.544  114.384 1.00 43.98  ? 245 LEU A N   1 
ATOM   1299  C CA  . LEU A 1 245 ? 137.318 87.986  115.358 1.00 35.77  ? 245 LEU A CA  1 
ATOM   1300  C C   . LEU A 1 245 ? 135.896 87.574  114.946 1.00 36.71  ? 245 LEU A C   1 
ATOM   1301  O O   . LEU A 1 245 ? 134.935 87.877  115.650 1.00 38.00  ? 245 LEU A O   1 
ATOM   1302  C CB  . LEU A 1 245 ? 137.379 89.514  115.527 1.00 37.06  ? 245 LEU A CB  1 
ATOM   1303  C CG  . LEU A 1 245 ? 138.688 90.075  116.094 1.00 39.58  ? 245 LEU A CG  1 
ATOM   1304  C CD1 . LEU A 1 245 ? 138.641 91.599  116.077 1.00 40.08  ? 245 LEU A CD1 1 
ATOM   1305  C CD2 . LEU A 1 245 ? 138.919 89.628  117.534 1.00 36.18  ? 245 LEU A CD2 1 
ATOM   1306  N N   . GLY A 1 246 ? 135.733 86.921  113.795 1.00 33.08  ? 246 GLY A N   1 
ATOM   1307  C CA  . GLY A 1 246 ? 134.448 86.619  113.181 1.00 25.62  ? 246 GLY A CA  1 
ATOM   1308  C C   . GLY A 1 246 ? 133.818 87.807  112.449 1.00 34.06  ? 246 GLY A C   1 
ATOM   1309  O O   . GLY A 1 246 ? 132.659 87.728  112.067 1.00 39.09  ? 246 GLY A O   1 
ATOM   1310  N N   . ASN A 1 247 ? 134.531 88.915  112.260 1.00 33.88  ? 247 ASN A N   1 
ATOM   1311  C CA  . ASN A 1 247 ? 134.005 90.097  111.589 1.00 25.19  ? 247 ASN A CA  1 
ATOM   1312  C C   . ASN A 1 247 ? 133.932 89.897  110.070 1.00 29.26  ? 247 ASN A C   1 
ATOM   1313  O O   . ASN A 1 247 ? 134.917 89.518  109.443 1.00 38.12  ? 247 ASN A O   1 
ATOM   1314  C CB  . ASN A 1 247 ? 134.865 91.315  111.967 1.00 24.05  ? 247 ASN A CB  1 
ATOM   1315  C CG  . ASN A 1 247 ? 134.649 91.799  113.383 1.00 26.15  ? 247 ASN A CG  1 
ATOM   1316  O OD1 . ASN A 1 247 ? 133.684 91.474  114.044 1.00 27.63  ? 247 ASN A OD1 1 
ATOM   1317  N ND2 . ASN A 1 247 ? 135.507 92.637  113.891 1.00 31.94  ? 247 ASN A ND2 1 
ATOM   1318  N N   . THR A 1 248 ? 132.776 90.183  109.475 1.00 30.79  ? 248 THR A N   1 
ATOM   1319  C CA  . THR A 1 248 ? 132.612 90.351  108.022 1.00 27.78  ? 248 THR A CA  1 
ATOM   1320  C C   . THR A 1 248 ? 133.132 91.717  107.567 1.00 20.28  ? 248 THR A C   1 
ATOM   1321  O O   . THR A 1 248 ? 133.506 92.558  108.380 1.00 33.21  ? 248 THR A O   1 
ATOM   1322  C CB  . THR A 1 248 ? 131.143 90.206  107.593 1.00 30.34  ? 248 THR A CB  1 
ATOM   1323  O OG1 . THR A 1 248 ? 130.366 91.286  108.066 1.00 34.73  ? 248 THR A OG1 1 
ATOM   1324  C CG2 . THR A 1 248 ? 130.493 88.901  108.031 1.00 27.88  ? 248 THR A CG2 1 
ATOM   1325  N N   . VAL A 1 249 ? 133.105 92.001  106.266 1.00 20.48  ? 249 VAL A N   1 
ATOM   1326  C CA  . VAL A 1 249 ? 133.399 93.348  105.752 1.00 24.97  ? 249 VAL A CA  1 
ATOM   1327  C C   . VAL A 1 249 ? 132.459 94.429  106.313 1.00 21.26  ? 249 VAL A C   1 
ATOM   1328  O O   . VAL A 1 249 ? 132.887 95.559  106.521 1.00 22.01  ? 249 VAL A O   1 
ATOM   1329  C CB  . VAL A 1 249 ? 133.428 93.332  104.214 1.00 25.94  ? 249 VAL A CB  1 
ATOM   1330  C CG1 . VAL A 1 249 ? 132.101 92.915  103.579 1.00 21.65  ? 249 VAL A CG1 1 
ATOM   1331  C CG2 . VAL A 1 249 ? 133.840 94.689  103.655 1.00 24.17  ? 249 VAL A CG2 1 
ATOM   1332  N N   . LEU A 1 250 ? 131.204 94.107  106.645 1.00 29.96  ? 250 LEU A N   1 
ATOM   1333  C CA  . LEU A 1 250 ? 130.271 95.063  107.252 1.00 23.13  ? 250 LEU A CA  1 
ATOM   1334  C C   . LEU A 1 250 ? 130.606 95.354  108.716 1.00 24.29  ? 250 LEU A C   1 
ATOM   1335  O O   . LEU A 1 250 ? 130.503 96.497  109.152 1.00 27.98  ? 250 LEU A O   1 
ATOM   1336  C CB  . LEU A 1 250 ? 128.827 94.559  107.122 1.00 21.02  ? 250 LEU A CB  1 
ATOM   1337  C CG  . LEU A 1 250 ? 128.303 94.406  105.688 1.00 25.33  ? 250 LEU A CG  1 
ATOM   1338  C CD1 . LEU A 1 250 ? 126.845 93.957  105.749 1.00 30.18  ? 250 LEU A CD1 1 
ATOM   1339  C CD2 . LEU A 1 250 ? 128.362 95.697  104.876 1.00 20.23  ? 250 LEU A CD2 1 
ATOM   1340  N N   . HIS A 1 251 ? 131.076 94.361  109.469 1.00 27.71  ? 251 HIS A N   1 
ATOM   1341  C CA  . HIS A 1 251 ? 131.646 94.579  110.799 1.00 15.90  ? 251 HIS A CA  1 
ATOM   1342  C C   . HIS A 1 251 ? 132.939 95.392  110.739 1.00 23.68  ? 251 HIS A C   1 
ATOM   1343  O O   . HIS A 1 251 ? 133.088 96.307  111.572 1.00 31.90  ? 251 HIS A O   1 
ATOM   1344  C CB  . HIS A 1 251 ? 131.916 93.233  111.488 1.00 19.81  ? 251 HIS A CB  1 
ATOM   1345  C CG  . HIS A 1 251 ? 130.693 92.432  111.789 1.00 18.53  ? 251 HIS A CG  1 
ATOM   1346  N ND1 . HIS A 1 251 ? 130.232 91.444  110.940 1.00 20.49  ? 251 HIS A ND1 1 
ATOM   1347  C CD2 . HIS A 1 251 ? 129.846 92.457  112.841 1.00 23.02  ? 251 HIS A CD2 1 
ATOM   1348  C CE1 . HIS A 1 251 ? 129.148 90.899  111.454 1.00 27.82  ? 251 HIS A CE1 1 
ATOM   1349  N NE2 . HIS A 1 251 ? 128.892 91.503  112.621 1.00 34.92  ? 251 HIS A NE2 1 
ATOM   1350  N N   . ALA A 1 252 ? 133.832 95.089  109.796 1.00 28.18  ? 252 ALA A N   1 
ATOM   1351  C CA  . ALA A 1 252 ? 135.061 95.838  109.578 1.00 11.95  ? 252 ALA A CA  1 
ATOM   1352  C C   . ALA A 1 252 ? 134.795 97.314  109.242 1.00 15.52  ? 252 ALA A C   1 
ATOM   1353  O O   . ALA A 1 252 ? 135.466 98.183  109.781 1.00 26.86  ? 252 ALA A O   1 
ATOM   1354  C CB  . ALA A 1 252 ? 135.873 95.144  108.488 1.00 18.76  ? 252 ALA A CB  1 
ATOM   1355  N N   . LEU A 1 253 ? 133.787 97.632  108.439 1.00 23.12  ? 253 LEU A N   1 
ATOM   1356  C CA  . LEU A 1 253 ? 133.393 99.015  108.173 1.00 20.48  ? 253 LEU A CA  1 
ATOM   1357  C C   . LEU A 1 253 ? 132.922 99.760  109.425 1.00 25.50  ? 253 LEU A C   1 
ATOM   1358  O O   . LEU A 1 253 ? 133.308 100.901 109.643 1.00 35.87  ? 253 LEU A O   1 
ATOM   1359  C CB  . LEU A 1 253 ? 132.311 99.011  107.089 1.00 22.31  ? 253 LEU A CB  1 
ATOM   1360  C CG  . LEU A 1 253 ? 132.916 98.931  105.685 1.00 27.24  ? 253 LEU A CG  1 
ATOM   1361  C CD1 . LEU A 1 253 ? 131.856 98.497  104.696 1.00 29.89  ? 253 LEU A CD1 1 
ATOM   1362  C CD2 . LEU A 1 253 ? 133.422 100.297 105.239 1.00 28.53  ? 253 LEU A CD2 1 
ATOM   1363  N N   . VAL A 1 254 ? 132.146 99.111  110.291 1.00 23.38  ? 254 VAL A N   1 
ATOM   1364  C CA  . VAL A 1 254 ? 131.797 99.654  111.609 1.00 19.83  ? 254 VAL A CA  1 
ATOM   1365  C C   . VAL A 1 254 ? 133.047 99.867  112.475 1.00 26.60  ? 254 VAL A C   1 
ATOM   1366  O O   . VAL A 1 254 ? 133.171 100.889 113.147 1.00 33.89  ? 254 VAL A O   1 
ATOM   1367  C CB  . VAL A 1 254 ? 130.752 98.746  112.283 1.00 23.87  ? 254 VAL A CB  1 
ATOM   1368  C CG1 . VAL A 1 254 ? 130.519 99.103  113.744 1.00 21.26  ? 254 VAL A CG1 1 
ATOM   1369  C CG2 . VAL A 1 254 ? 129.408 98.854  111.557 1.00 16.74  ? 254 VAL A CG2 1 
ATOM   1370  N N   . MET A 1 255 ? 134.022 98.962  112.433 1.00 22.15  ? 255 MET A N   1 
ATOM   1371  C CA  . MET A 1 255 ? 135.293 99.110  113.139 1.00 14.53  ? 255 MET A CA  1 
ATOM   1372  C C   . MET A 1 255 ? 136.177 100.255 112.619 1.00 23.85  ? 255 MET A C   1 
ATOM   1373  O O   . MET A 1 255 ? 136.812 100.897 113.447 1.00 31.57  ? 255 MET A O   1 
ATOM   1374  C CB  . MET A 1 255 ? 136.067 97.792  113.131 1.00 24.33  ? 255 MET A CB  1 
ATOM   1375  C CG  . MET A 1 255 ? 135.420 96.704  113.986 1.00 22.89  ? 255 MET A CG  1 
ATOM   1376  S SD  . MET A 1 255 ? 135.348 97.086  115.755 1.00 45.65  ? 255 MET A SD  1 
ATOM   1377  C CE  . MET A 1 255 ? 135.456 95.412  116.437 1.00 29.01  ? 255 MET A CE  1 
ATOM   1378  N N   . ILE A 1 256 ? 136.184 100.591 111.321 1.00 27.68  ? 256 ILE A N   1 
ATOM   1379  C CA  . ILE A 1 256 ? 136.958 101.773 110.820 1.00 25.01  ? 256 ILE A CA  1 
ATOM   1380  C C   . ILE A 1 256 ? 136.224 103.114 111.044 1.00 30.62  ? 256 ILE A C   1 
ATOM   1381  O O   . ILE A 1 256 ? 136.846 104.148 110.734 1.00 41.06  ? 256 ILE A O   1 
ATOM   1382  C CB  . ILE A 1 256 ? 137.312 101.583 109.330 1.00 27.54  ? 256 ILE A CB  1 
ATOM   1383  C CG1 . ILE A 1 256 ? 136.066 101.623 108.443 1.00 27.38  ? 256 ILE A CG1 1 
ATOM   1384  C CG2 . ILE A 1 256 ? 138.114 100.306 109.125 1.00 27.03  ? 256 ILE A CG2 1 
ATOM   1385  C CD1 . ILE A 1 256 ? 136.363 101.537 106.965 1.00 27.01  ? 256 ILE A CD1 1 
ATOM   1386  N N   . ALA A 1 257 ? 134.979 103.135 111.545 1.00 28.72  ? 257 ALA A N   1 
ATOM   1387  C CA  . ALA A 1 257 ? 134.257 104.383 111.695 1.00 25.99  ? 257 ALA A CA  1 
ATOM   1388  C C   . ALA A 1 257 ? 134.755 105.237 112.869 1.00 34.53  ? 257 ALA A C   1 
ATOM   1389  O O   . ALA A 1 257 ? 134.816 104.776 114.009 1.00 37.47  ? 257 ALA A O   1 
ATOM   1390  C CB  . ALA A 1 257 ? 132.765 104.059 111.812 1.00 24.71  ? 257 ALA A CB  1 
ATOM   1391  N N   . ASP A 1 258 ? 135.089 106.490 112.603 1.00 43.05  ? 258 ASP A N   1 
ATOM   1392  C CA  . ASP A 1 258 ? 135.119 107.603 113.575 1.00 43.07  ? 258 ASP A CA  1 
ATOM   1393  C C   . ASP A 1 258 ? 133.808 108.420 113.290 1.00 48.74  ? 258 ASP A C   1 
ATOM   1394  O O   . ASP A 1 258 ? 133.141 108.134 112.276 1.00 49.14  ? 258 ASP A O   1 
ATOM   1395  C CB  . ASP A 1 258 ? 136.392 108.441 113.450 1.00 47.09  ? 258 ASP A CB  1 
ATOM   1396  C CG  . ASP A 1 258 ? 136.370 109.395 112.268 1.00 51.53  ? 258 ASP A CG  1 
ATOM   1397  O OD1 . ASP A 1 258 ? 135.263 109.715 111.796 1.00 53.99  ? 258 ASP A OD1 1 
ATOM   1398  O OD2 . ASP A 1 258 ? 137.462 109.810 111.831 1.00 47.82  ? 258 ASP A OD2 1 
ATOM   1399  N N   . ASN A 1 259 ? 133.482 109.363 114.166 1.00 44.34  ? 259 ASN A N   1 
ATOM   1400  C CA  . ASN A 1 259 ? 132.222 110.100 114.064 1.00 45.47  ? 259 ASN A CA  1 
ATOM   1401  C C   . ASN A 1 259 ? 132.363 111.449 113.334 1.00 51.16  ? 259 ASN A C   1 
ATOM   1402  O O   . ASN A 1 259 ? 131.461 112.282 113.395 1.00 53.07  ? 259 ASN A O   1 
ATOM   1403  C CB  . ASN A 1 259 ? 131.570 110.134 115.454 1.00 47.98  ? 259 ASN A CB  1 
ATOM   1404  C CG  . ASN A 1 259 ? 131.331 108.727 115.976 1.00 42.84  ? 259 ASN A CG  1 
ATOM   1405  O OD1 . ASN A 1 259 ? 130.561 107.958 115.430 1.00 42.71  ? 259 ASN A OD1 1 
ATOM   1406  N ND2 . ASN A 1 259 ? 132.001 108.326 117.029 1.00 43.99  ? 259 ASN A ND2 1 
ATOM   1407  N N   . SER A 1 260 ? 133.477 111.681 112.628 1.00 53.19  ? 260 SER A N   1 
ATOM   1408  C CA  . SER A 1 260 ? 133.647 112.833 111.732 1.00 52.24  ? 260 SER A CA  1 
ATOM   1409  C C   . SER A 1 260 ? 132.780 112.681 110.469 1.00 52.92  ? 260 SER A C   1 
ATOM   1410  O O   . SER A 1 260 ? 132.500 111.553 110.047 1.00 51.49  ? 260 SER A O   1 
ATOM   1411  C CB  . SER A 1 260 ? 135.120 113.021 111.364 1.00 55.32  ? 260 SER A CB  1 
ATOM   1412  O OG  . SER A 1 260 ? 135.560 112.006 110.496 1.00 54.95  ? 260 SER A OG  1 
ATOM   1413  N N   . PRO A 1 261 ? 132.319 113.780 109.846 1.00 58.49  ? 261 PRO A N   1 
ATOM   1414  C CA  . PRO A 1 261 ? 131.313 113.706 108.786 1.00 56.57  ? 261 PRO A CA  1 
ATOM   1415  C C   . PRO A 1 261 ? 131.836 113.084 107.488 1.00 54.33  ? 261 PRO A C   1 
ATOM   1416  O O   . PRO A 1 261 ? 131.106 112.342 106.834 1.00 54.56  ? 261 PRO A O   1 
ATOM   1417  C CB  . PRO A 1 261 ? 130.824 115.143 108.589 1.00 54.71  ? 261 PRO A CB  1 
ATOM   1418  C CG  . PRO A 1 261 ? 131.972 116.001 109.108 1.00 54.24  ? 261 PRO A CG  1 
ATOM   1419  C CD  . PRO A 1 261 ? 132.549 115.160 110.237 1.00 52.77  ? 261 PRO A CD  1 
ATOM   1420  N N   . GLU A 1 262 ? 133.100 113.317 107.129 1.00 55.90  ? 262 GLU A N   1 
ATOM   1421  C CA  . GLU A 1 262 ? 133.716 112.720 105.940 1.00 57.87  ? 262 GLU A CA  1 
ATOM   1422  C C   . GLU A 1 262 ? 133.927 111.212 106.113 1.00 58.14  ? 262 GLU A C   1 
ATOM   1423  O O   . GLU A 1 262 ? 133.469 110.431 105.286 1.00 61.30  ? 262 GLU A O   1 
ATOM   1424  N N   . ASN A 1 263 ? 134.534 110.772 107.215 1.00 49.25  ? 263 ASN A N   1 
ATOM   1425  C CA  . ASN A 1 263 ? 134.685 109.342 107.483 1.00 46.54  ? 263 ASN A CA  1 
ATOM   1426  C C   . ASN A 1 263 ? 133.327 108.625 107.548 1.00 47.73  ? 263 ASN A C   1 
ATOM   1427  O O   . ASN A 1 263 ? 133.180 107.534 107.002 1.00 47.51  ? 263 ASN A O   1 
ATOM   1428  C CB  . ASN A 1 263 ? 135.459 109.153 108.787 1.00 45.76  ? 263 ASN A CB  1 
ATOM   1429  C CG  . ASN A 1 263 ? 135.611 107.686 109.111 1.00 46.36  ? 263 ASN A CG  1 
ATOM   1430  O OD1 . ASN A 1 263 ? 134.822 107.102 109.829 1.00 48.67  ? 263 ASN A OD1 1 
ATOM   1431  N ND2 . ASN A 1 263 ? 136.592 107.020 108.571 1.00 47.46  ? 263 ASN A ND2 1 
ATOM   1432  N N   . SER A 1 264 ? 132.316 109.259 108.142 1.00 47.72  ? 264 SER A N   1 
ATOM   1433  C CA  . SER A 1 264 ? 130.966 108.708 108.199 1.00 42.28  ? 264 SER A CA  1 
ATOM   1434  C C   . SER A 1 264 ? 130.367 108.550 106.807 1.00 41.62  ? 264 SER A C   1 
ATOM   1435  O O   . SER A 1 264 ? 129.912 107.462 106.475 1.00 42.97  ? 264 SER A O   1 
ATOM   1436  C CB  . SER A 1 264 ? 130.055 109.572 109.064 1.00 46.36  ? 264 SER A CB  1 
ATOM   1437  O OG  . SER A 1 264 ? 130.581 109.671 110.364 1.00 46.80  ? 264 SER A OG  1 
ATOM   1438  N N   . ALA A 1 265 ? 130.408 109.579 105.958 1.00 49.65  ? 265 ALA A N   1 
ATOM   1439  C CA  . ALA A 1 265 ? 129.890 109.501 104.593 1.00 49.28  ? 265 ALA A CA  1 
ATOM   1440  C C   . ALA A 1 265 ? 130.549 108.378 103.780 1.00 45.20  ? 265 ALA A C   1 
ATOM   1441  O O   . ALA A 1 265 ? 129.870 107.656 103.056 1.00 49.34  ? 265 ALA A O   1 
ATOM   1442  C CB  . ALA A 1 265 ? 130.093 110.860 103.920 1.00 46.66  ? 265 ALA A CB  1 
ATOM   1443  N N   . LEU A 1 266 ? 131.859 108.184 103.940 1.00 39.15  ? 266 LEU A N   1 
ATOM   1444  C CA  . LEU A 1 266 ? 132.613 107.142 103.249 1.00 43.73  ? 266 LEU A CA  1 
ATOM   1445  C C   . LEU A 1 266 ? 132.318 105.731 103.771 1.00 42.38  ? 266 LEU A C   1 
ATOM   1446  O O   . LEU A 1 266 ? 132.095 104.827 102.967 1.00 44.06  ? 266 LEU A O   1 
ATOM   1447  C CB  . LEU A 1 266 ? 134.108 107.496 103.304 1.00 48.84  ? 266 LEU A CB  1 
ATOM   1448  C CG  . LEU A 1 266 ? 134.441 108.822 102.591 1.00 49.43  ? 266 LEU A CG  1 
ATOM   1449  C CD1 . LEU A 1 266 ? 135.912 109.160 102.796 1.00 48.26  ? 266 LEU A CD1 1 
ATOM   1450  C CD2 . LEU A 1 266 ? 134.106 108.780 101.104 1.00 44.61  ? 266 LEU A CD2 1 
ATOM   1451  N N   . VAL A 1 267 ? 132.231 105.528 105.086 1.00 42.74  ? 267 VAL A N   1 
ATOM   1452  C CA  . VAL A 1 267 ? 131.789 104.246 105.664 1.00 38.93  ? 267 VAL A CA  1 
ATOM   1453  C C   . VAL A 1 267 ? 130.351 103.914 105.254 1.00 38.13  ? 267 VAL A C   1 
ATOM   1454  O O   . VAL A 1 267 ? 130.081 102.797 104.834 1.00 41.74  ? 267 VAL A O   1 
ATOM   1455  C CB  . VAL A 1 267 ? 131.958 104.237 107.195 1.00 38.99  ? 267 VAL A CB  1 
ATOM   1456  C CG1 . VAL A 1 267 ? 131.259 103.055 107.863 1.00 41.37  ? 267 VAL A CG1 1 
ATOM   1457  C CG2 . VAL A 1 267 ? 133.437 104.146 107.554 1.00 32.21  ? 267 VAL A CG2 1 
ATOM   1458  N N   . ILE A 1 268 ? 129.438 104.882 105.312 1.00 30.75  ? 268 ILE A N   1 
ATOM   1459  C CA  . ILE A 1 268 ? 128.031 104.727 104.935 1.00 35.51  ? 268 ILE A CA  1 
ATOM   1460  C C   . ILE A 1 268 ? 127.869 104.364 103.449 1.00 39.25  ? 268 ILE A C   1 
ATOM   1461  O O   . ILE A 1 268 ? 127.156 103.415 103.132 1.00 41.13  ? 268 ILE A O   1 
ATOM   1462  C CB  . ILE A 1 268 ? 127.253 105.998 105.345 1.00 35.82  ? 268 ILE A CB  1 
ATOM   1463  C CG1 . ILE A 1 268 ? 127.082 106.008 106.882 1.00 27.95  ? 268 ILE A CG1 1 
ATOM   1464  C CG2 . ILE A 1 268 ? 125.901 106.111 104.634 1.00 30.70  ? 268 ILE A CG2 1 
ATOM   1465  C CD1 . ILE A 1 268 ? 126.642 107.349 107.464 1.00 31.66  ? 268 ILE A CD1 1 
ATOM   1466  N N   . HIS A 1 269 ? 128.556 105.048 102.526 1.00 39.45  ? 269 HIS A N   1 
ATOM   1467  C CA  . HIS A 1 269 ? 128.490 104.707 101.100 1.00 41.19  ? 269 HIS A CA  1 
ATOM   1468  C C   . HIS A 1 269 ? 129.000 103.297 100.815 1.00 40.24  ? 269 HIS A C   1 
ATOM   1469  O O   . HIS A 1 269 ? 128.391 102.555 100.050 1.00 42.38  ? 269 HIS A O   1 
ATOM   1470  C CB  . HIS A 1 269 ? 129.270 105.722 100.248 1.00 45.24  ? 269 HIS A CB  1 
ATOM   1471  C CG  . HIS A 1 269 ? 128.540 107.018 100.007 1.00 49.32  ? 269 HIS A CG  1 
ATOM   1472  N ND1 . HIS A 1 269 ? 127.263 107.129 99.457  1.00 50.39  ? 269 HIS A ND1 1 
ATOM   1473  C CD2 . HIS A 1 269 ? 129.054 108.274 100.163 1.00 49.68  ? 269 HIS A CD2 1 
ATOM   1474  C CE1 . HIS A 1 269 ? 127.021 108.444 99.335  1.00 48.70  ? 269 HIS A CE1 1 
ATOM   1475  N NE2 . HIS A 1 269 ? 128.079 109.154 99.752  1.00 51.32  ? 269 HIS A NE2 1 
ATOM   1476  N N   . MET A 1 270 ? 130.105 102.903 101.442 1.00 37.54  ? 270 MET A N   1 
ATOM   1477  C CA  . MET A 1 270 ? 130.682 101.576 101.269 1.00 35.45  ? 270 MET A CA  1 
ATOM   1478  C C   . MET A 1 270 ? 129.787 100.480 101.857 1.00 34.54  ? 270 MET A C   1 
ATOM   1479  O O   . MET A 1 270 ? 129.550 99.462  101.211 1.00 35.64  ? 270 MET A O   1 
ATOM   1480  C CB  . MET A 1 270 ? 132.072 101.582 101.904 1.00 30.50  ? 270 MET A CB  1 
ATOM   1481  C CG  . MET A 1 270 ? 132.964 100.434 101.428 1.00 33.33  ? 270 MET A CG  1 
ATOM   1482  S SD  . MET A 1 270 ? 133.459 100.416 99.678  1.00 50.01  ? 270 MET A SD  1 
ATOM   1483  C CE  . MET A 1 270 ? 133.792 102.162 99.352  1.00 33.81  ? 270 MET A CE  1 
ATOM   1484  N N   . TYR A 1 271 ? 129.223 100.712 103.043 1.00 32.75  ? 271 TYR A N   1 
ATOM   1485  C CA  . TYR A 1 271 ? 128.298 99.807  103.719 1.00 24.68  ? 271 TYR A CA  1 
ATOM   1486  C C   . TYR A 1 271 ? 127.016 99.569  102.900 1.00 33.32  ? 271 TYR A C   1 
ATOM   1487  O O   . TYR A 1 271 ? 126.637 98.423  102.677 1.00 32.03  ? 271 TYR A O   1 
ATOM   1488  C CB  . TYR A 1 271 ? 128.011 100.385 105.115 1.00 29.68  ? 271 TYR A CB  1 
ATOM   1489  C CG  . TYR A 1 271 ? 127.293 99.446  106.057 1.00 28.78  ? 271 TYR A CG  1 
ATOM   1490  C CD1 . TYR A 1 271 ? 125.923 99.189  105.882 1.00 29.57  ? 271 TYR A CD1 1 
ATOM   1491  C CD2 . TYR A 1 271 ? 127.997 98.822  107.105 1.00 27.27  ? 271 TYR A CD2 1 
ATOM   1492  C CE1 . TYR A 1 271 ? 125.268 98.275  106.717 1.00 27.51  ? 271 TYR A CE1 1 
ATOM   1493  C CE2 . TYR A 1 271 ? 127.335 97.918  107.953 1.00 34.58  ? 271 TYR A CE2 1 
ATOM   1494  C CZ  . TYR A 1 271 ? 125.974 97.629  107.747 1.00 30.57  ? 271 TYR A CZ  1 
ATOM   1495  O OH  . TYR A 1 271 ? 125.327 96.752  108.544 1.00 31.93  ? 271 TYR A OH  1 
ATOM   1496  N N   . ASP A 1 272 ? 126.379 100.628 102.399 1.00 34.76  ? 272 ASP A N   1 
ATOM   1497  C CA  . ASP A 1 272 ? 125.201 100.513 101.536 1.00 31.24  ? 272 ASP A CA  1 
ATOM   1498  C C   . ASP A 1 272 ? 125.512 99.832  100.205 1.00 37.95  ? 272 ASP A C   1 
ATOM   1499  O O   . ASP A 1 272 ? 124.744 98.983  99.758  1.00 41.13  ? 272 ASP A O   1 
ATOM   1500  C CB  . ASP A 1 272 ? 124.606 101.896 101.255 1.00 39.06  ? 272 ASP A CB  1 
ATOM   1501  C CG  . ASP A 1 272 ? 123.853 102.521 102.430 1.00 44.94  ? 272 ASP A CG  1 
ATOM   1502  O OD1 . ASP A 1 272 ? 123.624 101.850 103.459 1.00 38.57  ? 272 ASP A OD1 1 
ATOM   1503  O OD2 . ASP A 1 272 ? 123.420 103.685 102.276 1.00 48.63  ? 272 ASP A OD2 1 
ATOM   1504  N N   . GLY A 1 273 ? 126.650 100.154 99.584  1.00 42.45  ? 273 GLY A N   1 
ATOM   1505  C CA  . GLY A 1 273 ? 127.112 99.508  98.367  1.00 31.66  ? 273 GLY A CA  1 
ATOM   1506  C C   . GLY A 1 273 ? 127.274 98.005  98.547  1.00 34.31  ? 273 GLY A C   1 
ATOM   1507  O O   . GLY A 1 273 ? 126.814 97.233  97.711  1.00 40.70  ? 273 GLY A O   1 
ATOM   1508  N N   . LEU A 1 274 ? 127.881 97.552  99.642  1.00 34.18  ? 274 LEU A N   1 
ATOM   1509  C CA  . LEU A 1 274 ? 128.069 96.127  99.901  1.00 35.65  ? 274 LEU A CA  1 
ATOM   1510  C C   . LEU A 1 274 ? 126.758 95.392  100.206 1.00 39.69  ? 274 LEU A C   1 
ATOM   1511  O O   . LEU A 1 274 ? 126.603 94.253  99.778  1.00 40.38  ? 274 LEU A O   1 
ATOM   1512  C CB  . LEU A 1 274 ? 129.075 95.951  101.036 1.00 33.09  ? 274 LEU A CB  1 
ATOM   1513  C CG  . LEU A 1 274 ? 130.502 96.367  100.660 1.00 34.17  ? 274 LEU A CG  1 
ATOM   1514  C CD1 . LEU A 1 274 ? 131.284 96.519  101.944 1.00 36.90  ? 274 LEU A CD1 1 
ATOM   1515  C CD2 . LEU A 1 274 ? 131.235 95.343  99.804  1.00 30.35  ? 274 LEU A CD2 1 
ATOM   1516  N N   . LEU A 1 275 ? 125.781 96.016  100.869 1.00 40.52  ? 275 LEU A N   1 
ATOM   1517  C CA  . LEU A 1 275 ? 124.441 95.433  100.985 1.00 37.48  ? 275 LEU A CA  1 
ATOM   1518  C C   . LEU A 1 275 ? 123.743 95.293  99.633  1.00 37.73  ? 275 LEU A C   1 
ATOM   1519  O O   . LEU A 1 275 ? 123.172 94.245  99.348  1.00 40.51  ? 275 LEU A O   1 
ATOM   1520  C CB  . LEU A 1 275 ? 123.553 96.281  101.898 1.00 39.89  ? 275 LEU A CB  1 
ATOM   1521  C CG  . LEU A 1 275 ? 123.860 96.186  103.390 1.00 36.61  ? 275 LEU A CG  1 
ATOM   1522  C CD1 . LEU A 1 275 ? 122.839 97.053  104.112 1.00 33.31  ? 275 LEU A CD1 1 
ATOM   1523  C CD2 . LEU A 1 275 ? 123.721 94.765  103.923 1.00 33.25  ? 275 LEU A CD2 1 
ATOM   1524  N N   . GLN A 1 276 ? 123.854 96.328  98.799  1.00 41.74  ? 276 GLN A N   1 
ATOM   1525  C CA  . GLN A 1 276 ? 123.266 96.272  97.431  1.00 38.63  ? 276 GLN A CA  1 
ATOM   1526  C C   . GLN A 1 276 ? 123.952 95.145  96.656  1.00 47.72  ? 276 GLN A C   1 
ATOM   1527  O O   . GLN A 1 276 ? 123.225 94.357  96.019  1.00 51.34  ? 276 GLN A O   1 
ATOM   1528  C CB  . GLN A 1 276 ? 123.401 97.629  96.740  1.00 41.81  ? 276 GLN A CB  1 
ATOM   1529  C CG  . GLN A 1 276 ? 122.593 98.723  97.422  1.00 42.18  ? 276 GLN A CG  1 
ATOM   1530  C CD  . GLN A 1 276 ? 122.343 99.907  96.522  1.00 49.93  ? 276 GLN A CD  1 
ATOM   1531  O OE1 . GLN A 1 276 ? 122.901 100.013 95.433  1.00 52.54  ? 276 GLN A OE1 1 
ATOM   1532  N NE2 . GLN A 1 276 ? 121.489 100.811 96.974  1.00 48.66  ? 276 GLN A NE2 1 
ATOM   1533  N N   . MET A 1 277 ? 125.287 95.052  96.704  1.00 49.97  ? 277 MET A N   1 
ATOM   1534  C CA  . MET A 1 277 ? 126.020 93.938  96.099  1.00 48.63  ? 277 MET A CA  1 
ATOM   1535  C C   . MET A 1 277 ? 125.555 92.582  96.631  1.00 46.20  ? 277 MET A C   1 
ATOM   1536  O O   . MET A 1 277 ? 125.306 91.677  95.841  1.00 51.66  ? 277 MET A O   1 
ATOM   1537  C CB  . MET A 1 277 ? 127.531 94.098  96.327  1.00 50.79  ? 277 MET A CB  1 
ATOM   1538  C CG  . MET A 1 277 ? 128.140 95.201  95.469  1.00 48.27  ? 277 MET A CG  1 
ATOM   1539  S SD  . MET A 1 277 ? 128.339 94.746  93.734  1.00 69.24  ? 277 MET A SD  1 
ATOM   1540  C CE  . MET A 1 277 ? 128.236 96.386  92.990  1.00 58.70  ? 277 MET A CE  1 
ATOM   1541  N N   . GLY A 1 278 ? 125.372 92.415  97.940  1.00 46.73  ? 278 GLY A N   1 
ATOM   1542  C CA  . GLY A 1 278 ? 124.863 91.177  98.527  1.00 47.91  ? 278 GLY A CA  1 
ATOM   1543  C C   . GLY A 1 278 ? 123.467 90.806  98.032  1.00 48.92  ? 278 GLY A C   1 
ATOM   1544  O O   . GLY A 1 278 ? 123.204 89.644  97.733  1.00 49.41  ? 278 GLY A O   1 
ATOM   1545  N N   . ALA A 1 279 ? 122.597 91.794  97.826  1.00 49.60  ? 279 ALA A N   1 
ATOM   1546  C CA  . ALA A 1 279 ? 121.281 91.615  97.227  1.00 48.29  ? 279 ALA A CA  1 
ATOM   1547  C C   . ALA A 1 279 ? 121.312 91.100  95.770  1.00 54.46  ? 279 ALA A C   1 
ATOM   1548  O O   . ALA A 1 279 ? 120.306 90.582  95.290  1.00 56.63  ? 279 ALA A O   1 
ATOM   1549  C CB  . ALA A 1 279 ? 120.537 92.946  97.344  1.00 46.44  ? 279 ALA A CB  1 
ATOM   1550  N N   . ARG A 1 280 ? 122.508 91.118  95.143  1.00 57.81  ? 280 ARG A N   1 
ATOM   1551  C CA  . ARG A 1 280 ? 122.695 90.631  93.739  1.00 52.49  ? 280 ARG A CA  1 
ATOM   1552  C C   . ARG A 1 280 ? 123.572 89.382  93.673  1.00 55.16  ? 280 ARG A C   1 
ATOM   1553  O O   . ARG A 1 280 ? 123.375 88.583  92.739  1.00 59.55  ? 280 ARG A O   1 
ATOM   1554  C CB  . ARG A 1 280 ? 123.478 91.637  92.884  1.00 54.75  ? 280 ARG A CB  1 
ATOM   1555  C CG  . ARG A 1 280 ? 122.709 92.939  92.610  1.00 56.41  ? 280 ARG A CG  1 
ATOM   1556  C CD  . ARG A 1 280 ? 123.605 94.013  91.987  1.00 58.94  ? 280 ARG A CD  1 
ATOM   1557  N NE  . ARG A 1 280 ? 124.279 93.519  90.795  1.00 61.25  ? 280 ARG A NE  1 
ATOM   1558  C CZ  . ARG A 1 280 ? 125.448 92.890  90.799  1.00 60.77  ? 280 ARG A CZ  1 
ATOM   1559  N NH1 . ARG A 1 280 ? 125.980 92.477  89.661  1.00 57.67  ? 280 ARG A NH1 1 
ATOM   1560  N NH2 . ARG A 1 280 ? 126.082 92.675  91.938  1.00 57.95  ? 280 ARG A NH2 1 
ATOM   1561  N N   . LEU A 1 281 ? 124.502 89.217  94.611  1.00 54.01  ? 281 LEU A N   1 
ATOM   1562  C CA  . LEU A 1 281 ? 125.507 88.146  94.580  1.00 52.67  ? 281 LEU A CA  1 
ATOM   1563  C C   . LEU A 1 281 ? 125.247 86.994  95.555  1.00 52.16  ? 281 LEU A C   1 
ATOM   1564  O O   . LEU A 1 281 ? 125.696 85.875  95.313  1.00 55.13  ? 281 LEU A O   1 
ATOM   1565  C CB  . LEU A 1 281 ? 126.883 88.758  94.868  1.00 51.21  ? 281 LEU A CB  1 
ATOM   1566  C CG  . LEU A 1 281 ? 127.337 89.817  93.852  1.00 54.03  ? 281 LEU A CG  1 
ATOM   1567  C CD1 . LEU A 1 281 ? 128.620 90.448  94.360  1.00 55.20  ? 281 LEU A CD1 1 
ATOM   1568  C CD2 . LEU A 1 281 ? 127.599 89.218  92.475  1.00 52.03  ? 281 LEU A CD2 1 
ATOM   1569  N N   . CYS A 1 282 ? 124.523 87.241  96.642  1.00 53.10  ? 282 CYS A N   1 
ATOM   1570  C CA  . CYS A 1 282 ? 124.109 86.230  97.613  1.00 51.35  ? 282 CYS A CA  1 
ATOM   1571  C C   . CYS A 1 282 ? 122.711 86.564  98.172  1.00 54.30  ? 282 CYS A C   1 
ATOM   1572  O O   . CYS A 1 282 ? 122.547 86.731  99.381  1.00 57.03  ? 282 CYS A O   1 
ATOM   1573  C CB  . CYS A 1 282 ? 125.215 86.049  98.673  1.00 53.08  ? 282 CYS A CB  1 
ATOM   1574  S SG  . CYS A 1 282 ? 125.694 87.599  99.491  1.00 55.21  ? 282 CYS A SG  1 
ATOM   1575  N N   . PRO A 1 283 ? 121.664 86.649  97.326  1.00 58.04  ? 283 PRO A N   1 
ATOM   1576  C CA  . PRO A 1 283 ? 120.356 87.194  97.704  1.00 57.18  ? 283 PRO A CA  1 
ATOM   1577  C C   . PRO A 1 283 ? 119.621 86.382  98.783  1.00 57.37  ? 283 PRO A C   1 
ATOM   1578  O O   . PRO A 1 283 ? 118.773 86.917  99.493  1.00 57.58  ? 283 PRO A O   1 
ATOM   1579  C CB  . PRO A 1 283 ? 119.554 87.247  96.402  1.00 54.58  ? 283 PRO A CB  1 
ATOM   1580  C CG  . PRO A 1 283 ? 120.191 86.177  95.526  1.00 57.67  ? 283 PRO A CG  1 
ATOM   1581  C CD  . PRO A 1 283 ? 121.658 86.247  95.926  1.00 57.53  ? 283 PRO A CD  1 
ATOM   1582  N N   . THR A 1 284 ? 119.960 85.103  98.942  1.00 58.52  ? 284 THR A N   1 
ATOM   1583  C CA  . THR A 1 284 ? 119.461 84.241  100.023 1.00 59.03  ? 284 THR A CA  1 
ATOM   1584  C C   . THR A 1 284 ? 120.031 84.596  101.411 1.00 58.07  ? 284 THR A C   1 
ATOM   1585  O O   . THR A 1 284 ? 119.471 84.195  102.432 1.00 58.47  ? 284 THR A O   1 
ATOM   1586  C CB  . THR A 1 284 ? 119.709 82.766  99.655  1.00 61.76  ? 284 THR A CB  1 
ATOM   1587  O OG1 . THR A 1 284 ? 118.961 81.908  100.478 1.00 63.95  ? 284 THR A OG1 1 
ATOM   1588  C CG2 . THR A 1 284 ? 121.167 82.319  99.766  1.00 58.13  ? 284 THR A CG2 1 
ATOM   1589  N N   . VAL A 1 285 ? 121.123 85.365  101.486 1.00 54.61  ? 285 VAL A N   1 
ATOM   1590  C CA  . VAL A 1 285 ? 121.868 85.621  102.730 1.00 52.48  ? 285 VAL A CA  1 
ATOM   1591  C C   . VAL A 1 285 ? 121.562 87.001  103.306 1.00 52.63  ? 285 VAL A C   1 
ATOM   1592  O O   . VAL A 1 285 ? 121.736 88.028  102.652 1.00 53.61  ? 285 VAL A O   1 
ATOM   1593  C CB  . VAL A 1 285 ? 123.385 85.456  102.531 1.00 53.07  ? 285 VAL A CB  1 
ATOM   1594  C CG1 . VAL A 1 285 ? 124.138 85.653  103.847 1.00 52.30  ? 285 VAL A CG1 1 
ATOM   1595  C CG2 . VAL A 1 285 ? 123.725 84.064  102.004 1.00 52.40  ? 285 VAL A CG2 1 
ATOM   1596  N N   . GLN A 1 286 ? 121.158 87.023  104.575 1.00 51.26  ? 286 GLN A N   1 
ATOM   1597  C CA  . GLN A 1 286 ? 121.022 88.227  105.389 1.00 49.21  ? 286 GLN A CA  1 
ATOM   1598  C C   . GLN A 1 286 ? 122.386 88.620  105.988 1.00 47.29  ? 286 GLN A C   1 
ATOM   1599  O O   . GLN A 1 286 ? 122.753 88.169  107.071 1.00 47.30  ? 286 GLN A O   1 
ATOM   1600  C CB  . GLN A 1 286 ? 119.980 87.958  106.488 1.00 50.01  ? 286 GLN A CB  1 
ATOM   1601  C CG  . GLN A 1 286 ? 118.551 87.727  105.974 1.00 49.38  ? 286 GLN A CG  1 
ATOM   1602  C CD  . GLN A 1 286 ? 117.816 89.038  105.723 1.00 56.44  ? 286 GLN A CD  1 
ATOM   1603  O OE1 . GLN A 1 286 ? 117.755 89.549  104.615 1.00 55.17  ? 286 GLN A OE1 1 
ATOM   1604  N NE2 . GLN A 1 286 ? 117.241 89.634  106.742 1.00 54.56  ? 286 GLN A NE2 1 
ATOM   1605  N N   . LEU A 1 287 ? 123.161 89.462  105.297 1.00 41.88  ? 287 LEU A N   1 
ATOM   1606  C CA  . LEU A 1 287 ? 124.530 89.816  105.713 1.00 36.66  ? 287 LEU A CA  1 
ATOM   1607  C C   . LEU A 1 287 ? 124.603 90.529  107.072 1.00 42.31  ? 287 LEU A C   1 
ATOM   1608  O O   . LEU A 1 287 ? 125.569 90.364  107.809 1.00 43.55  ? 287 LEU A O   1 
ATOM   1609  C CB  . LEU A 1 287 ? 125.187 90.704  104.646 1.00 38.54  ? 287 LEU A CB  1 
ATOM   1610  C CG  . LEU A 1 287 ? 125.419 90.051  103.278 1.00 40.81  ? 287 LEU A CG  1 
ATOM   1611  C CD1 . LEU A 1 287 ? 125.988 91.099  102.330 1.00 38.96  ? 287 LEU A CD1 1 
ATOM   1612  C CD2 . LEU A 1 287 ? 126.404 88.891  103.347 1.00 41.07  ? 287 LEU A CD2 1 
ATOM   1613  N N   . GLU A 1 288 ? 123.576 91.291  107.434 1.00 39.27  ? 288 GLU A N   1 
ATOM   1614  C CA  . GLU A 1 288 ? 123.483 91.963  108.733 1.00 29.86  ? 288 GLU A CA  1 
ATOM   1615  C C   . GLU A 1 288 ? 123.019 91.056  109.878 1.00 35.20  ? 288 GLU A C   1 
ATOM   1616  O O   . GLU A 1 288 ? 122.989 91.497  111.019 1.00 44.90  ? 288 GLU A O   1 
ATOM   1617  C CB  . GLU A 1 288 ? 122.534 93.154  108.648 1.00 35.90  ? 288 GLU A CB  1 
ATOM   1618  C CG  . GLU A 1 288 ? 122.974 94.180  107.618 1.00 31.43  ? 288 GLU A CG  1 
ATOM   1619  C CD  . GLU A 1 288 ? 122.182 95.467  107.799 1.00 40.78  ? 288 GLU A CD  1 
ATOM   1620  O OE1 . GLU A 1 288 ? 120.935 95.420  107.763 1.00 47.11  ? 288 GLU A OE1 1 
ATOM   1621  O OE2 . GLU A 1 288 ? 122.793 96.539  107.975 1.00 38.59  ? 288 GLU A OE2 1 
ATOM   1622  N N   . GLU A 1 289 ? 122.635 89.807  109.619 1.00 38.07  ? 289 GLU A N   1 
ATOM   1623  C CA  . GLU A 1 289 ? 122.304 88.836  110.672 1.00 40.72  ? 289 GLU A CA  1 
ATOM   1624  C C   . GLU A 1 289 ? 123.505 87.970  111.074 1.00 43.23  ? 289 GLU A C   1 
ATOM   1625  O O   . GLU A 1 289 ? 123.432 87.231  112.054 1.00 48.39  ? 289 GLU A O   1 
ATOM   1626  C CB  . GLU A 1 289 ? 121.114 87.962  110.255 1.00 44.13  ? 289 GLU A CB  1 
ATOM   1627  C CG  . GLU A 1 289 ? 119.810 88.766  110.192 1.00 43.46  ? 289 GLU A CG  1 
ATOM   1628  C CD  . GLU A 1 289 ? 118.582 87.899  109.860 1.00 51.38  ? 289 GLU A CD  1 
ATOM   1629  O OE1 . GLU A 1 289 ? 118.545 86.707  110.236 1.00 50.78  ? 289 GLU A OE1 1 
ATOM   1630  O OE2 . GLU A 1 289 ? 117.640 88.424  109.233 1.00 54.53  ? 289 GLU A OE2 1 
ATOM   1631  N N   . ILE A 1 290 ? 124.621 88.059  110.345 1.00 42.16  ? 290 ILE A N   1 
ATOM   1632  C CA  . ILE A 1 290 ? 125.863 87.363  110.679 1.00 35.38  ? 290 ILE A CA  1 
ATOM   1633  C C   . ILE A 1 290 ? 126.430 87.958  111.972 1.00 33.93  ? 290 ILE A C   1 
ATOM   1634  O O   . ILE A 1 290 ? 126.647 89.163  112.071 1.00 39.00  ? 290 ILE A O   1 
ATOM   1635  C CB  . ILE A 1 290 ? 126.874 87.427  109.509 1.00 37.21  ? 290 ILE A CB  1 
ATOM   1636  C CG1 . ILE A 1 290 ? 126.292 86.771  108.239 1.00 33.88  ? 290 ILE A CG1 1 
ATOM   1637  C CG2 . ILE A 1 290 ? 128.190 86.737  109.908 1.00 36.23  ? 290 ILE A CG2 1 
ATOM   1638  C CD1 . ILE A 1 290 ? 127.103 87.011  106.970 1.00 36.59  ? 290 ILE A CD1 1 
ATOM   1639  N N   . SER A 1 291 ? 126.700 87.109  112.963 1.00 33.53  ? 291 SER A N   1 
ATOM   1640  C CA  . SER A 1 291 ? 127.298 87.504  114.238 1.00 27.98  ? 291 SER A CA  1 
ATOM   1641  C C   . SER A 1 291 ? 128.789 87.189  114.277 1.00 36.38  ? 291 SER A C   1 
ATOM   1642  O O   . SER A 1 291 ? 129.209 86.104  113.877 1.00 44.46  ? 291 SER A O   1 
ATOM   1643  C CB  . SER A 1 291 ? 126.593 86.824  115.408 1.00 28.48  ? 291 SER A CB  1 
ATOM   1644  O OG  . SER A 1 291 ? 125.292 87.341  115.547 1.00 37.22  ? 291 SER A OG  1 
ATOM   1645  N N   . ASN A 1 292 ? 129.598 88.117  114.770 1.00 31.91  ? 292 ASN A N   1 
ATOM   1646  C CA  . ASN A 1 292 ? 131.010 87.866  115.052 1.00 32.35  ? 292 ASN A CA  1 
ATOM   1647  C C   . ASN A 1 292 ? 131.196 86.961  116.294 1.00 29.53  ? 292 ASN A C   1 
ATOM   1648  O O   . ASN A 1 292 ? 130.223 86.516  116.904 1.00 39.16  ? 292 ASN A O   1 
ATOM   1649  C CB  . ASN A 1 292 ? 131.754 89.214  115.096 1.00 26.06  ? 292 ASN A CB  1 
ATOM   1650  C CG  . ASN A 1 292 ? 131.516 90.064  116.319 1.00 25.93  ? 292 ASN A CG  1 
ATOM   1651  O OD1 . ASN A 1 292 ? 130.892 89.663  117.285 1.00 33.55  ? 292 ASN A OD1 1 
ATOM   1652  N ND2 . ASN A 1 292 ? 132.036 91.255  116.329 1.00 28.64  ? 292 ASN A ND2 1 
ATOM   1653  N N   . HIS A 1 293 ? 132.431 86.667  116.703 1.00 34.59  ? 293 HIS A N   1 
ATOM   1654  C CA  . HIS A 1 293 ? 132.697 85.786  117.857 1.00 35.06  ? 293 HIS A CA  1 
ATOM   1655  C C   . HIS A 1 293 ? 132.206 86.338  119.201 1.00 33.97  ? 293 HIS A C   1 
ATOM   1656  O O   . HIS A 1 293 ? 131.977 85.565  120.126 1.00 40.06  ? 293 HIS A O   1 
ATOM   1657  C CB  . HIS A 1 293 ? 134.196 85.463  117.929 1.00 33.07  ? 293 HIS A CB  1 
ATOM   1658  C CG  . HIS A 1 293 ? 134.746 84.697  116.752 1.00 34.90  ? 293 HIS A CG  1 
ATOM   1659  N ND1 . HIS A 1 293 ? 136.101 84.497  116.503 1.00 42.46  ? 293 HIS A ND1 1 
ATOM   1660  C CD2 . HIS A 1 293 ? 134.028 84.040  115.796 1.00 34.43  ? 293 HIS A CD2 1 
ATOM   1661  C CE1 . HIS A 1 293 ? 136.173 83.751  115.391 1.00 40.23  ? 293 HIS A CE1 1 
ATOM   1662  N NE2 . HIS A 1 293 ? 134.941 83.465  114.947 1.00 36.34  ? 293 HIS A NE2 1 
ATOM   1663  N N   . GLN A 1 294 ? 132.002 87.654  119.322 1.00 37.59  ? 294 GLN A N   1 
ATOM   1664  C CA  . GLN A 1 294 ? 131.362 88.289  120.480 1.00 37.26  ? 294 GLN A CA  1 
ATOM   1665  C C   . GLN A 1 294 ? 129.819 88.224  120.441 1.00 41.81  ? 294 GLN A C   1 
ATOM   1666  O O   . GLN A 1 294 ? 129.158 88.759  121.329 1.00 43.28  ? 294 GLN A O   1 
ATOM   1667  C CB  . GLN A 1 294 ? 131.849 89.739  120.637 1.00 36.68  ? 294 GLN A CB  1 
ATOM   1668  C CG  . GLN A 1 294 ? 133.363 89.841  120.841 1.00 41.30  ? 294 GLN A CG  1 
ATOM   1669  C CD  . GLN A 1 294 ? 133.849 91.249  121.181 1.00 48.68  ? 294 GLN A CD  1 
ATOM   1670  O OE1 . GLN A 1 294 ? 133.094 92.156  121.505 1.00 49.02  ? 294 GLN A OE1 1 
ATOM   1671  N NE2 . GLN A 1 294 ? 135.138 91.487  121.139 1.00 44.33  ? 294 GLN A NE2 1 
ATOM   1672  N N   . GLY A 1 295 ? 129.227 87.597  119.418 1.00 38.61  ? 295 GLY A N   1 
ATOM   1673  C CA  . GLY A 1 295 ? 127.781 87.496  119.235 1.00 33.27  ? 295 GLY A CA  1 
ATOM   1674  C C   . GLY A 1 295 ? 127.127 88.776  118.710 1.00 38.98  ? 295 GLY A C   1 
ATOM   1675  O O   . GLY A 1 295 ? 125.933 88.975  118.911 1.00 44.31  ? 295 GLY A O   1 
ATOM   1676  N N   . LEU A 1 296 ? 127.890 89.663  118.071 1.00 33.55  ? 296 LEU A N   1 
ATOM   1677  C CA  . LEU A 1 296 ? 127.408 90.959  117.598 1.00 24.93  ? 296 LEU A CA  1 
ATOM   1678  C C   . LEU A 1 296 ? 127.198 90.942  116.084 1.00 22.90  ? 296 LEU A C   1 
ATOM   1679  O O   . LEU A 1 296 ? 128.080 90.559  115.323 1.00 31.16  ? 296 LEU A O   1 
ATOM   1680  C CB  . LEU A 1 296 ? 128.392 92.071  117.994 1.00 24.38  ? 296 LEU A CB  1 
ATOM   1681  C CG  . LEU A 1 296 ? 128.681 92.178  119.498 1.00 25.97  ? 296 LEU A CG  1 
ATOM   1682  C CD1 . LEU A 1 296 ? 129.888 93.073  119.714 1.00 30.68  ? 296 LEU A CD1 1 
ATOM   1683  C CD2 . LEU A 1 296 ? 127.517 92.768  120.276 1.00 23.43  ? 296 LEU A CD2 1 
ATOM   1684  N N   . THR A 1 297 ? 126.039 91.403  115.633 1.00 29.86  ? 297 THR A N   1 
ATOM   1685  C CA  . THR A 1 297 ? 125.797 91.822  114.250 1.00 24.33  ? 297 THR A CA  1 
ATOM   1686  C C   . THR A 1 297 ? 126.404 93.210  113.997 1.00 20.55  ? 297 THR A C   1 
ATOM   1687  O O   . THR A 1 297 ? 126.755 93.889  114.961 1.00 31.00  ? 297 THR A O   1 
ATOM   1688  C CB  . THR A 1 297 ? 124.291 91.851  113.976 1.00 27.18  ? 297 THR A CB  1 
ATOM   1689  O OG1 . THR A 1 297 ? 123.641 92.780  114.808 1.00 33.94  ? 297 THR A OG1 1 
ATOM   1690  C CG2 . THR A 1 297 ? 123.629 90.498  114.186 1.00 20.54  ? 297 THR A CG2 1 
ATOM   1691  N N   . PRO A 1 298 ? 126.534 93.698  112.751 1.00 18.71  ? 298 PRO A N   1 
ATOM   1692  C CA  . PRO A 1 298 ? 127.063 95.040  112.501 1.00 17.52  ? 298 PRO A CA  1 
ATOM   1693  C C   . PRO A 1 298 ? 126.335 96.174  113.251 1.00 17.44  ? 298 PRO A C   1 
ATOM   1694  O O   . PRO A 1 298 ? 126.994 97.066  113.769 1.00 22.84  ? 298 PRO A O   1 
ATOM   1695  C CB  . PRO A 1 298 ? 126.990 95.211  110.989 1.00 20.19  ? 298 PRO A CB  1 
ATOM   1696  C CG  . PRO A 1 298 ? 127.087 93.790  110.450 1.00 10.15  ? 298 PRO A CG  1 
ATOM   1697  C CD  . PRO A 1 298 ? 126.344 92.979  111.498 1.00 14.12  ? 298 PRO A CD  1 
ATOM   1698  N N   . LEU A 1 299 ? 125.003 96.125  113.399 1.00 17.48  ? 299 LEU A N   1 
ATOM   1699  C CA  . LEU A 1 299 ? 124.233 97.107  114.181 1.00 13.01  ? 299 LEU A CA  1 
ATOM   1700  C C   . LEU A 1 299 ? 124.525 97.036  115.688 1.00 22.21  ? 299 LEU A C   1 
ATOM   1701  O O   . LEU A 1 299 ? 124.698 98.063  116.336 1.00 22.81  ? 299 LEU A O   1 
ATOM   1702  C CB  . LEU A 1 299 ? 122.734 96.894  113.901 1.00 15.92  ? 299 LEU A CB  1 
ATOM   1703  C CG  . LEU A 1 299 ? 121.795 97.821  114.691 1.00 18.92  ? 299 LEU A CG  1 
ATOM   1704  C CD1 . LEU A 1 299 ? 121.931 99.288  114.307 1.00 16.51  ? 299 LEU A CD1 1 
ATOM   1705  C CD2 . LEU A 1 299 ? 120.350 97.398  114.486 1.00 17.57  ? 299 LEU A CD2 1 
ATOM   1706  N N   . LYS A 1 300 ? 124.620 95.828  116.249 1.00 23.63  ? 300 LYS A N   1 
ATOM   1707  C CA  . LYS A 1 300 ? 125.002 95.604  117.649 1.00 8.45   ? 300 LYS A CA  1 
ATOM   1708  C C   . LYS A 1 300 ? 126.445 96.014  117.930 1.00 18.42  ? 300 LYS A C   1 
ATOM   1709  O O   . LYS A 1 300 ? 126.723 96.575  118.980 1.00 19.93  ? 300 LYS A O   1 
ATOM   1710  C CB  . LYS A 1 300 ? 124.770 94.136  118.013 1.00 21.30  ? 300 LYS A CB  1 
ATOM   1711  C CG  . LYS A 1 300 ? 123.286 93.780  118.128 1.00 19.51  ? 300 LYS A CG  1 
ATOM   1712  C CD  . LYS A 1 300 ? 123.121 92.344  118.632 1.00 19.44  ? 300 LYS A CD  1 
ATOM   1713  C CE  . LYS A 1 300 ? 121.651 91.936  118.603 1.00 21.92  ? 300 LYS A CE  1 
ATOM   1714  N NZ  . LYS A 1 300 ? 121.435 90.616  119.241 1.00 30.28  ? 300 LYS A NZ  1 
ATOM   1715  N N   . LEU A 1 301 ? 127.363 95.786  116.993 1.00 25.60  ? 301 LEU A N   1 
ATOM   1716  C CA  . LEU A 1 301 ? 128.735 96.276  117.067 1.00 10.90  ? 301 LEU A CA  1 
ATOM   1717  C C   . LEU A 1 301 ? 128.808 97.804  116.960 1.00 17.34  ? 301 LEU A C   1 
ATOM   1718  O O   . LEU A 1 301 ? 129.558 98.422  117.704 1.00 26.60  ? 301 LEU A O   1 
ATOM   1719  C CB  . LEU A 1 301 ? 129.561 95.563  115.989 1.00 28.60  ? 301 LEU A CB  1 
ATOM   1720  C CG  . LEU A 1 301 ? 131.060 95.897  116.038 1.00 25.01  ? 301 LEU A CG  1 
ATOM   1721  C CD1 . LEU A 1 301 ? 131.721 95.325  117.282 1.00 22.47  ? 301 LEU A CD1 1 
ATOM   1722  C CD2 . LEU A 1 301 ? 131.752 95.308  114.821 1.00 18.00  ? 301 LEU A CD2 1 
ATOM   1723  N N   . ALA A 1 302 ? 128.001 98.440  116.111 1.00 21.02  ? 302 ALA A N   1 
ATOM   1724  C CA  . ALA A 1 302 ? 127.940 99.897  116.036 1.00 21.88  ? 302 ALA A CA  1 
ATOM   1725  C C   . ALA A 1 302 ? 127.427 100.514 117.346 1.00 18.90  ? 302 ALA A C   1 
ATOM   1726  O O   . ALA A 1 302 ? 127.993 101.488 117.828 1.00 21.27  ? 302 ALA A O   1 
ATOM   1727  C CB  . ALA A 1 302 ? 127.099 100.309 114.824 1.00 12.83  ? 302 ALA A CB  1 
ATOM   1728  N N   . ALA A 1 303 ? 126.423 99.897  117.977 1.00 22.88  ? 303 ALA A N   1 
ATOM   1729  C CA  . ALA A 1 303 ? 125.961 100.246 119.315 1.00 15.38  ? 303 ALA A CA  1 
ATOM   1730  C C   . ALA A 1 303 ? 127.036 100.018 120.396 1.00 24.60  ? 303 ALA A C   1 
ATOM   1731  O O   . ALA A 1 303 ? 127.268 100.896 121.218 1.00 29.84  ? 303 ALA A O   1 
ATOM   1732  C CB  . ALA A 1 303 ? 124.700 99.435  119.611 1.00 24.93  ? 303 ALA A CB  1 
ATOM   1733  N N   . LYS A 1 304 ? 127.732 98.874  120.408 1.00 29.96  ? 304 LYS A N   1 
ATOM   1734  C CA  . LYS A 1 304 ? 128.751 98.571  121.420 1.00 20.38  ? 304 LYS A CA  1 
ATOM   1735  C C   . LYS A 1 304 ? 129.946 99.507  121.342 1.00 18.54  ? 304 LYS A C   1 
ATOM   1736  O O   . LYS A 1 304 ? 130.396 100.030 122.355 1.00 32.35  ? 304 LYS A O   1 
ATOM   1737  C CB  . LYS A 1 304 ? 129.198 97.108  121.311 1.00 21.09  ? 304 LYS A CB  1 
ATOM   1738  C CG  . LYS A 1 304 ? 130.080 96.743  122.509 1.00 30.04  ? 304 LYS A CG  1 
ATOM   1739  C CD  . LYS A 1 304 ? 130.511 95.284  122.470 1.00 34.83  ? 304 LYS A CD  1 
ATOM   1740  C CE  . LYS A 1 304 ? 131.447 94.985  123.640 1.00 34.85  ? 304 LYS A CE  1 
ATOM   1741  N NZ  . LYS A 1 304 ? 131.880 93.568  123.646 1.00 36.77  ? 304 LYS A NZ  1 
ATOM   1742  N N   . GLU A 1 305 ? 130.461 99.739  120.145 1.00 28.13  ? 305 GLU A N   1 
ATOM   1743  C CA  . GLU A 1 305 ? 131.649 100.557 119.915 1.00 21.07  ? 305 GLU A CA  1 
ATOM   1744  C C   . GLU A 1 305 ? 131.346 102.064 119.843 1.00 25.61  ? 305 GLU A C   1 
ATOM   1745  O O   . GLU A 1 305 ? 132.249 102.860 119.604 1.00 33.40  ? 305 GLU A O   1 
ATOM   1746  C CB  . GLU A 1 305 ? 132.385 100.036 118.674 1.00 21.28  ? 305 GLU A CB  1 
ATOM   1747  C CG  . GLU A 1 305 ? 132.810 98.560  118.734 1.00 25.37  ? 305 GLU A CG  1 
ATOM   1748  C CD  . GLU A 1 305 ? 133.714 98.206  119.924 1.00 32.00  ? 305 GLU A CD  1 
ATOM   1749  O OE1 . GLU A 1 305 ? 134.429 99.096  120.440 1.00 36.97  ? 305 GLU A OE1 1 
ATOM   1750  O OE2 . GLU A 1 305 ? 133.734 97.029  120.336 1.00 36.71  ? 305 GLU A OE2 1 
ATOM   1751  N N   . GLY A 1 306 ? 130.096 102.479 120.059 1.00 11.72  ? 306 GLY A N   1 
ATOM   1752  C CA  . GLY A 1 306 ? 129.686 103.883 120.099 1.00 9.37   ? 306 GLY A CA  1 
ATOM   1753  C C   . GLY A 1 306 ? 129.757 104.606 118.757 1.00 19.24  ? 306 GLY A C   1 
ATOM   1754  O O   . GLY A 1 306 ? 130.012 105.807 118.716 1.00 30.45  ? 306 GLY A O   1 
ATOM   1755  N N   . LYS A 1 307 ? 129.589 103.887 117.643 1.00 27.57  ? 307 LYS A N   1 
ATOM   1756  C CA  . LYS A 1 307 ? 129.751 104.414 116.283 1.00 22.61  ? 307 LYS A CA  1 
ATOM   1757  C C   . LYS A 1 307 ? 128.457 105.069 115.827 1.00 20.17  ? 307 LYS A C   1 
ATOM   1758  O O   . LYS A 1 307 ? 127.746 104.543 114.985 1.00 23.49  ? 307 LYS A O   1 
ATOM   1759  C CB  . LYS A 1 307 ? 130.245 103.305 115.338 1.00 18.76  ? 307 LYS A CB  1 
ATOM   1760  C CG  . LYS A 1 307 ? 131.491 102.567 115.824 1.00 13.17  ? 307 LYS A CG  1 
ATOM   1761  C CD  . LYS A 1 307 ? 132.641 103.518 116.167 1.00 17.47  ? 307 LYS A CD  1 
ATOM   1762  C CE  . LYS A 1 307 ? 133.944 102.778 116.466 1.00 24.71  ? 307 LYS A CE  1 
ATOM   1763  N NZ  . LYS A 1 307 ? 134.626 102.309 115.239 1.00 21.56  ? 307 LYS A NZ  1 
ATOM   1764  N N   . ILE A 1 308 ? 128.106 106.186 116.447 1.00 24.81  ? 308 ILE A N   1 
ATOM   1765  C CA  . ILE A 1 308 ? 126.767 106.770 116.381 1.00 27.76  ? 308 ILE A CA  1 
ATOM   1766  C C   . ILE A 1 308 ? 126.317 107.145 114.966 1.00 25.90  ? 308 ILE A C   1 
ATOM   1767  O O   . ILE A 1 308 ? 125.139 107.018 114.649 1.00 30.17  ? 308 ILE A O   1 
ATOM   1768  C CB  . ILE A 1 308 ? 126.642 107.938 117.380 1.00 33.40  ? 308 ILE A CB  1 
ATOM   1769  C CG1 . ILE A 1 308 ? 125.193 108.449 117.374 1.00 35.40  ? 308 ILE A CG1 1 
ATOM   1770  C CG2 . ILE A 1 308 ? 127.633 109.077 117.106 1.00 25.71  ? 308 ILE A CG2 1 
ATOM   1771  C CD1 . ILE A 1 308 ? 124.862 109.344 118.554 1.00 26.87  ? 308 ILE A CD1 1 
ATOM   1772  N N   . GLU A 1 309 ? 127.224 107.574 114.094 1.00 33.00  ? 309 GLU A N   1 
ATOM   1773  C CA  . GLU A 1 309 ? 126.873 108.001 112.740 1.00 31.64  ? 309 GLU A CA  1 
ATOM   1774  C C   . GLU A 1 309 ? 126.457 106.821 111.843 1.00 28.67  ? 309 GLU A C   1 
ATOM   1775  O O   . GLU A 1 309 ? 125.405 106.871 111.210 1.00 33.10  ? 309 GLU A O   1 
ATOM   1776  C CB  . GLU A 1 309 ? 128.039 108.796 112.143 1.00 34.52  ? 309 GLU A CB  1 
ATOM   1777  C CG  . GLU A 1 309 ? 128.428 110.031 112.977 1.00 29.62  ? 309 GLU A CG  1 
ATOM   1778  C CD  . GLU A 1 309 ? 127.275 111.030 113.116 1.00 39.76  ? 309 GLU A CD  1 
ATOM   1779  O OE1 . GLU A 1 309 ? 126.624 111.345 112.097 1.00 38.84  ? 309 GLU A OE1 1 
ATOM   1780  O OE2 . GLU A 1 309 ? 126.963 111.487 114.238 1.00 42.35  ? 309 GLU A OE2 1 
ATOM   1781  N N   . ILE A 1 310 ? 127.220 105.725 111.837 1.00 20.17  ? 310 ILE A N   1 
ATOM   1782  C CA  . ILE A 1 310 ? 126.841 104.489 111.134 1.00 17.68  ? 310 ILE A CA  1 
ATOM   1783  C C   . ILE A 1 310 ? 125.720 103.736 111.862 1.00 21.24  ? 310 ILE A C   1 
ATOM   1784  O O   . ILE A 1 310 ? 124.875 103.134 111.213 1.00 34.42  ? 310 ILE A O   1 
ATOM   1785  C CB  . ILE A 1 310 ? 128.079 103.614 110.820 1.00 23.57  ? 310 ILE A CB  1 
ATOM   1786  C CG1 . ILE A 1 310 ? 127.781 102.362 109.969 1.00 31.86  ? 310 ILE A CG1 1 
ATOM   1787  C CG2 . ILE A 1 310 ? 128.795 103.130 112.083 1.00 20.72  ? 310 ILE A CG2 1 
ATOM   1788  C CD1 . ILE A 1 310 ? 127.172 102.653 108.598 1.00 28.47  ? 310 ILE A CD1 1 
ATOM   1789  N N   . PHE A 1 311 ? 125.638 103.821 113.189 1.00 25.94  ? 311 PHE A N   1 
ATOM   1790  C CA  . PHE A 1 311 ? 124.534 103.277 113.973 1.00 16.36  ? 311 PHE A CA  1 
ATOM   1791  C C   . PHE A 1 311 ? 123.202 103.933 113.599 1.00 19.12  ? 311 PHE A C   1 
ATOM   1792  O O   . PHE A 1 311 ? 122.277 103.229 113.213 1.00 23.88  ? 311 PHE A O   1 
ATOM   1793  C CB  . PHE A 1 311 ? 124.845 103.441 115.466 1.00 17.49  ? 311 PHE A CB  1 
ATOM   1794  C CG  . PHE A 1 311 ? 123.721 103.026 116.381 1.00 14.11  ? 311 PHE A CG  1 
ATOM   1795  C CD1 . PHE A 1 311 ? 123.431 101.665 116.551 1.00 16.57  ? 311 PHE A CD1 1 
ATOM   1796  C CD2 . PHE A 1 311 ? 122.936 103.996 117.029 1.00 13.75  ? 311 PHE A CD2 1 
ATOM   1797  C CE1 . PHE A 1 311 ? 122.333 101.274 117.322 1.00 18.21  ? 311 PHE A CE1 1 
ATOM   1798  C CE2 . PHE A 1 311 ? 121.853 103.601 117.826 1.00 16.90  ? 311 PHE A CE2 1 
ATOM   1799  C CZ  . PHE A 1 311 ? 121.542 102.244 117.954 1.00 22.51  ? 311 PHE A CZ  1 
ATOM   1800  N N   . ARG A 1 312 ? 123.123 105.271 113.614 1.00 19.19  ? 312 ARG A N   1 
ATOM   1801  C CA  . ARG A 1 312 ? 121.954 106.031 113.161 1.00 12.33  ? 312 ARG A CA  1 
ATOM   1802  C C   . ARG A 1 312 ? 121.594 105.687 111.724 1.00 27.71  ? 312 ARG A C   1 
ATOM   1803  O O   . ARG A 1 312 ? 120.426 105.464 111.434 1.00 34.01  ? 312 ARG A O   1 
ATOM   1804  C CB  . ARG A 1 312 ? 122.234 107.536 113.279 1.00 21.53  ? 312 ARG A CB  1 
ATOM   1805  C CG  . ARG A 1 312 ? 120.975 108.380 113.042 1.00 23.09  ? 312 ARG A CG  1 
ATOM   1806  C CD  . ARG A 1 312 ? 121.259 109.863 112.796 1.00 28.73  ? 312 ARG A CD  1 
ATOM   1807  N NE  . ARG A 1 312 ? 122.184 110.445 113.787 1.00 37.09  ? 312 ARG A NE  1 
ATOM   1808  C CZ  . ARG A 1 312 ? 123.446 110.783 113.584 1.00 36.45  ? 312 ARG A CZ  1 
ATOM   1809  N NH1 . ARG A 1 312 ? 124.185 111.192 114.567 1.00 30.38  ? 312 ARG A NH1 1 
ATOM   1810  N NH2 . ARG A 1 312 ? 123.991 110.718 112.411 1.00 29.65  ? 312 ARG A NH2 1 
ATOM   1811  N N   . HIS A 1 313 ? 122.588 105.620 110.838 1.00 25.52  ? 313 HIS A N   1 
ATOM   1812  C CA  . HIS A 1 313 ? 122.366 105.277 109.448 1.00 23.12  ? 313 HIS A CA  1 
ATOM   1813  C C   . HIS A 1 313 ? 121.718 103.905 109.298 1.00 23.51  ? 313 HIS A C   1 
ATOM   1814  O O   . HIS A 1 313 ? 120.655 103.851 108.650 1.00 32.28  ? 313 HIS A O   1 
ATOM   1815  C CB  . HIS A 1 313 ? 123.702 105.328 108.692 1.00 25.43  ? 313 HIS A CB  1 
ATOM   1816  C CG  . HIS A 1 313 ? 123.708 104.519 107.441 1.00 37.42  ? 313 HIS A CG  1 
ATOM   1817  N ND1 . HIS A 1 313 ? 123.150 104.977 106.264 1.00 22.71  ? 313 HIS A ND1 1 
ATOM   1818  C CD2 . HIS A 1 313 ? 124.193 103.286 107.179 1.00 39.50  ? 313 HIS A CD2 1 
ATOM   1819  C CE1 . HIS A 1 313 ? 123.294 104.061 105.329 1.00 26.56  ? 313 HIS A CE1 1 
ATOM   1820  N NE2 . HIS A 1 313 ? 123.932 103.015 105.865 1.00 37.15  ? 313 HIS A NE2 1 
ATOM   1821  N N   . ILE A 1 314 ? 122.293 102.835 109.858 1.00 19.37  ? 314 ILE A N   1 
ATOM   1822  C CA  . ILE A 1 314 ? 121.722 101.486 109.763 1.00 20.66  ? 314 ILE A CA  1 
ATOM   1823  C C   . ILE A 1 314 ? 120.307 101.497 110.361 1.00 19.02  ? 314 ILE A C   1 
ATOM   1824  O O   . ILE A 1 314 ? 119.385 101.013 109.678 1.00 29.86  ? 314 ILE A O   1 
ATOM   1825  C CB  . ILE A 1 314 ? 122.592 100.445 110.506 1.00 23.89  ? 314 ILE A CB  1 
ATOM   1826  C CG1 . ILE A 1 314 ? 123.999 100.344 109.915 1.00 23.14  ? 314 ILE A CG1 1 
ATOM   1827  C CG2 . ILE A 1 314 ? 121.882 99.080  110.543 1.00 19.76  ? 314 ILE A CG2 1 
ATOM   1828  C CD1 . ILE A 1 314 ? 124.913 99.400  110.662 1.00 22.05  ? 314 ILE A CD1 1 
ATOM   1829  N N   . LEU A 1 315 ? 120.141 102.030 111.576 1.00 23.75  ? 315 LEU A N   1 
ATOM   1830  C CA  . LEU A 1 315 ? 118.835 101.987 112.301 1.00 25.28  ? 315 LEU A CA  1 
ATOM   1831  C C   . LEU A 1 315 ? 117.717 102.720 111.550 1.00 27.09  ? 315 LEU A C   1 
ATOM   1832  O O   . LEU A 1 315 ? 116.582 102.257 111.617 1.00 25.44  ? 315 LEU A O   1 
ATOM   1833  C CB  . LEU A 1 315 ? 119.067 102.626 113.674 1.00 24.64  ? 315 LEU A CB  1 
ATOM   1834  C CG  . LEU A 1 315 ? 117.840 102.743 114.574 1.00 35.98  ? 315 LEU A CG  1 
ATOM   1835  C CD1 . LEU A 1 315 ? 117.374 101.368 115.028 1.00 32.44  ? 315 LEU A CD1 1 
ATOM   1836  C CD2 . LEU A 1 315 ? 118.149 103.624 115.774 1.00 25.32  ? 315 LEU A CD2 1 
ATOM   1837  N N   . GLN A 1 316 ? 117.994 103.803 110.826 1.00 33.59  ? 316 GLN A N   1 
ATOM   1838  C CA  . GLN A 1 316 ? 117.014 104.633 110.124 1.00 26.49  ? 316 GLN A CA  1 
ATOM   1839  C C   . GLN A 1 316 ? 117.020 104.458 108.593 1.00 21.29  ? 316 GLN A C   1 
ATOM   1840  O O   . GLN A 1 316 ? 116.452 105.283 107.878 1.00 32.62  ? 316 GLN A O   1 
ATOM   1841  C CB  . GLN A 1 316 ? 117.215 106.102 110.526 1.00 20.24  ? 316 GLN A CB  1 
ATOM   1842  C CG  . GLN A 1 316 ? 117.230 106.319 112.046 1.00 30.59  ? 316 GLN A CG  1 
ATOM   1843  C CD  . GLN A 1 316 ? 117.403 107.769 112.450 1.00 29.59  ? 316 GLN A CD  1 
ATOM   1844  O OE1 . GLN A 1 316 ? 117.731 108.648 111.668 1.00 32.37  ? 316 GLN A OE1 1 
ATOM   1845  N NE2 . GLN A 1 316 ? 117.203 108.070 113.708 1.00 24.62  ? 316 GLN A NE2 1 
ATOM   1846  N N   . ARG A 1 317 ? 117.704 103.421 108.090 1.00 22.22  ? 317 ARG A N   1 
ATOM   1847  C CA  . ARG A 1 317 ? 117.922 103.228 106.621 1.00 33.27  ? 317 ARG A CA  1 
ATOM   1848  C C   . ARG A 1 317 ? 116.639 102.966 105.827 1.00 30.60  ? 317 ARG A C   1 
ATOM   1849  O O   . ARG A 1 317 ? 115.829 102.132 106.275 1.00 32.73  ? 317 ARG A O   1 
ATOM   1850  C CB  . ARG A 1 317 ? 118.895 102.058 106.480 1.00 29.30  ? 317 ARG A CB  1 
ATOM   1851  C CG  . ARG A 1 317 ? 119.460 101.895 105.072 1.00 25.10  ? 317 ARG A CG  1 
ATOM   1852  C CD  . ARG A 1 317 ? 120.528 100.803 105.091 1.00 35.92  ? 317 ARG A CD  1 
ATOM   1853  N NE  . ARG A 1 317 ? 119.980 99.476  105.335 1.00 34.36  ? 317 ARG A NE  1 
ATOM   1854  C CZ  . ARG A 1 317 ? 119.876 98.911  106.533 1.00 28.56  ? 317 ARG A CZ  1 
ATOM   1855  N NH1 . ARG A 1 317 ? 119.365 97.699  106.653 1.00 30.45  ? 317 ARG A NH1 1 
ATOM   1856  N NH2 . ARG A 1 317 ? 120.287 99.561  107.608 1.00 40.48  ? 317 ARG A NH2 1 
ATOM   1857  N N   . GLU A 1 318 ? 116.468 103.653 104.694 1.00 34.63  ? 318 GLU A N   1 
ATOM   1858  C CA  . GLU A 1 318 ? 115.352 103.448 103.765 1.00 30.10  ? 318 GLU A CA  1 
ATOM   1859  C C   . GLU A 1 318 ? 115.794 103.438 102.291 1.00 36.37  ? 318 GLU A C   1 
ATOM   1860  O O   . GLU A 1 318 ? 116.642 104.231 101.887 1.00 38.19  ? 318 GLU A O   1 
ATOM   1861  C CB  . GLU A 1 318 ? 114.257 104.493 104.038 1.00 36.17  ? 318 GLU A CB  1 
ATOM   1862  C CG  . GLU A 1 318 ? 113.005 104.235 103.190 1.00 38.84  ? 318 GLU A CG  1 
ATOM   1863  C CD  . GLU A 1 318 ? 111.765 105.010 103.658 1.00 42.73  ? 318 GLU A CD  1 
ATOM   1864  O OE1 . GLU A 1 318 ? 111.906 106.059 104.325 1.00 46.32  ? 318 GLU A OE1 1 
ATOM   1865  O OE2 . GLU A 1 318 ? 110.644 104.592 103.298 1.00 38.33  ? 318 GLU A OE2 1 
ATOM   1866  N N   . PHE A 1 319 ? 115.184 102.565 101.483 1.00 44.55  ? 319 PHE A N   1 
ATOM   1867  C CA  . PHE A 1 319 ? 115.379 102.434 100.016 1.00 37.85  ? 319 PHE A CA  1 
ATOM   1868  C C   . PHE A 1 319 ? 114.031 102.168 99.305  1.00 46.51  ? 319 PHE A C   1 
ATOM   1869  O O   . PHE A 1 319 ? 113.030 101.900 99.998  1.00 47.26  ? 319 PHE A O   1 
ATOM   1870  C CB  . PHE A 1 319 ? 116.318 101.273 99.685  1.00 36.75  ? 319 PHE A CB  1 
ATOM   1871  C CG  . PHE A 1 319 ? 117.614 101.235 100.453 1.00 42.37  ? 319 PHE A CG  1 
ATOM   1872  C CD1 . PHE A 1 319 ? 118.633 102.129 100.171 1.00 45.23  ? 319 PHE A CD1 1 
ATOM   1873  C CD2 . PHE A 1 319 ? 117.823 100.287 101.441 1.00 41.95  ? 319 PHE A CD2 1 
ATOM   1874  C CE1 . PHE A 1 319 ? 119.828 102.087 100.871 1.00 40.34  ? 319 PHE A CE1 1 
ATOM   1875  C CE2 . PHE A 1 319 ? 119.018 100.243 102.140 1.00 40.43  ? 319 PHE A CE2 1 
ATOM   1876  C CZ  . PHE A 1 319 ? 120.019 101.143 101.853 1.00 40.88  ? 319 PHE A CZ  1 
ATOM   1877  N N   . SER A 1 320 ? 114.026 102.236 97.968  1.00 57.85  ? 320 SER A N   1 
ATOM   1878  C CA  . SER A 1 320 ? 112.850 102.070 97.087  1.00 56.28  ? 320 SER A CA  1 
ATOM   1879  C C   . SER A 1 320 ? 113.187 101.278 95.810  1.00 56.01  ? 320 SER A C   1 
ATOM   1880  O O   . SER A 1 320 ? 114.364 101.126 95.470  1.00 55.32  ? 320 SER A O   1 
ATOM   1881  C CB  . SER A 1 320 ? 112.268 103.445 96.754  1.00 53.75  ? 320 SER A CB  1 
ATOM   1882  O OG  . SER A 1 320 ? 113.225 104.258 96.106  1.00 58.82  ? 320 SER A OG  1 
ATOM   1883  N N   . GLY A 1 321 ? 112.195 100.723 95.121  1.00 57.85  ? 321 GLY A N   1 
ATOM   1884  C CA  . GLY A 1 321 ? 112.453 99.844  93.980  1.00 57.04  ? 321 GLY A CA  1 
ATOM   1885  C C   . GLY A 1 321 ? 113.117 98.532  94.420  1.00 57.26  ? 321 GLY A C   1 
ATOM   1886  O O   . GLY A 1 321 ? 112.603 97.881  95.334  1.00 58.67  ? 321 GLY A O   1 
ATOM   1887  N N   . PRO A 1 322 ? 114.241 98.109  93.814  1.00 56.12  ? 322 PRO A N   1 
ATOM   1888  C CA  . PRO A 1 322 ? 114.793 96.771  94.028  1.00 54.60  ? 322 PRO A CA  1 
ATOM   1889  C C   . PRO A 1 322 ? 115.380 96.566  95.431  1.00 53.71  ? 322 PRO A C   1 
ATOM   1890  O O   . PRO A 1 322 ? 115.367 95.456  95.955  1.00 54.93  ? 322 PRO A O   1 
ATOM   1891  C CB  . PRO A 1 322 ? 115.864 96.612  92.945  1.00 52.56  ? 322 PRO A CB  1 
ATOM   1892  C CG  . PRO A 1 322 ? 116.318 98.041  92.662  1.00 53.50  ? 322 PRO A CG  1 
ATOM   1893  C CD  . PRO A 1 322 ? 115.037 98.844  92.844  1.00 52.15  ? 322 PRO A CD  1 
ATOM   1894  N N   . TYR A 1 323 ? 115.881 97.639  96.052  1.00 48.59  ? 323 TYR A N   1 
ATOM   1895  C CA  . TYR A 1 323 ? 116.574 97.602  97.340  1.00 45.39  ? 323 TYR A CA  1 
ATOM   1896  C C   . TYR A 1 323 ? 115.678 97.872  98.550  1.00 49.38  ? 323 TYR A C   1 
ATOM   1897  O O   . TYR A 1 323 ? 116.159 97.849  99.674  1.00 49.70  ? 323 TYR A O   1 
ATOM   1898  C CB  . TYR A 1 323 ? 117.787 98.543  97.281  1.00 45.00  ? 323 TYR A CB  1 
ATOM   1899  C CG  . TYR A 1 323 ? 118.793 98.180  96.202  1.00 49.38  ? 323 TYR A CG  1 
ATOM   1900  C CD1 . TYR A 1 323 ? 119.296 96.865  96.106  1.00 48.18  ? 323 TYR A CD1 1 
ATOM   1901  C CD2 . TYR A 1 323 ? 119.229 99.162  95.294  1.00 47.60  ? 323 TYR A CD2 1 
ATOM   1902  C CE1 . TYR A 1 323 ? 120.218 96.534  95.098  1.00 46.48  ? 323 TYR A CE1 1 
ATOM   1903  C CE2 . TYR A 1 323 ? 120.160 98.836  94.293  1.00 45.79  ? 323 TYR A CE2 1 
ATOM   1904  C CZ  . TYR A 1 323 ? 120.653 97.522  94.193  1.00 50.01  ? 323 TYR A CZ  1 
ATOM   1905  O OH  . TYR A 1 323 ? 121.574 97.209  93.244  1.00 50.53  ? 323 TYR A OH  1 
ATOM   1906  N N   . GLN A 1 324 ? 114.378 98.089  98.359  1.00 48.14  ? 324 GLN A N   1 
ATOM   1907  C CA  . GLN A 1 324 ? 113.437 98.357  99.447  1.00 42.85  ? 324 GLN A CA  1 
ATOM   1908  C C   . GLN A 1 324 ? 113.497 97.328  100.601 1.00 44.68  ? 324 GLN A C   1 
ATOM   1909  O O   . GLN A 1 324 ? 113.507 97.774  101.749 1.00 43.91  ? 324 GLN A O   1 
ATOM   1910  C CB  . GLN A 1 324 ? 112.036 98.561  98.849  1.00 46.74  ? 324 GLN A CB  1 
ATOM   1911  C CG  . GLN A 1 324 ? 110.991 99.105  99.837  1.00 47.44  ? 324 GLN A CG  1 
ATOM   1912  C CD  . GLN A 1 324 ? 110.141 98.040  100.520 1.00 47.99  ? 324 GLN A CD  1 
ATOM   1913  O OE1 . GLN A 1 324 ? 110.415 96.852  100.495 1.00 50.34  ? 324 GLN A OE1 1 
ATOM   1914  N NE2 . GLN A 1 324 ? 109.063 98.435  101.151 1.00 46.16  ? 324 GLN A NE2 1 
ATOM   1915  N N   . PRO A 1 325 ? 113.662 96.007  100.372 1.00 46.69  ? 325 PRO A N   1 
ATOM   1916  C CA  . PRO A 1 325 ? 113.836 95.027  101.448 1.00 45.60  ? 325 PRO A CA  1 
ATOM   1917  C C   . PRO A 1 325 ? 115.078 95.236  102.330 1.00 41.63  ? 325 PRO A C   1 
ATOM   1918  O O   . PRO A 1 325 ? 115.117 94.747  103.456 1.00 45.69  ? 325 PRO A O   1 
ATOM   1919  C CB  . PRO A 1 325 ? 113.909 93.660  100.760 1.00 45.82  ? 325 PRO A CB  1 
ATOM   1920  C CG  . PRO A 1 325 ? 113.194 93.883  99.439  1.00 45.17  ? 325 PRO A CG  1 
ATOM   1921  C CD  . PRO A 1 325 ? 113.576 95.315  99.097  1.00 38.94  ? 325 PRO A CD  1 
ATOM   1922  N N   . LEU A 1 326 ? 116.095 95.968  101.872 1.00 41.86  ? 326 LEU A N   1 
ATOM   1923  C CA  . LEU A 1 326 ? 117.263 96.323  102.684 1.00 36.72  ? 326 LEU A CA  1 
ATOM   1924  C C   . LEU A 1 326 ? 116.982 97.472  103.667 1.00 38.91  ? 326 LEU A C   1 
ATOM   1925  O O   . LEU A 1 326 ? 117.856 97.841  104.441 1.00 46.61  ? 326 LEU A O   1 
ATOM   1926  C CB  . LEU A 1 326 ? 118.456 96.668  101.774 1.00 40.92  ? 326 LEU A CB  1 
ATOM   1927  C CG  . LEU A 1 326 ? 118.982 95.543  100.875 1.00 38.39  ? 326 LEU A CG  1 
ATOM   1928  C CD1 . LEU A 1 326 ? 120.007 96.140  99.913  1.00 38.11  ? 326 LEU A CD1 1 
ATOM   1929  C CD2 . LEU A 1 326 ? 119.647 94.449  101.698 1.00 36.75  ? 326 LEU A CD2 1 
ATOM   1930  N N   . SER A 1 327 ? 115.796 98.073  103.657 1.00 36.25  ? 327 SER A N   1 
ATOM   1931  C CA  . SER A 1 327 ? 115.413 99.134  104.594 1.00 29.97  ? 327 SER A CA  1 
ATOM   1932  C C   . SER A 1 327 ? 115.218 98.609  106.017 1.00 31.75  ? 327 SER A C   1 
ATOM   1933  O O   . SER A 1 327 ? 114.784 97.478  106.218 1.00 32.83  ? 327 SER A O   1 
ATOM   1934  C CB  . SER A 1 327 ? 114.113 99.808  104.156 1.00 32.56  ? 327 SER A CB  1 
ATOM   1935  O OG  . SER A 1 327 ? 114.167 100.187 102.804 1.00 36.29  ? 327 SER A OG  1 
ATOM   1936  N N   . ARG A 1 328 ? 115.479 99.459  107.015 1.00 31.08  ? 328 ARG A N   1 
ATOM   1937  C CA  . ARG A 1 328 ? 114.990 99.313  108.395 1.00 23.68  ? 328 ARG A CA  1 
ATOM   1938  C C   . ARG A 1 328 ? 113.882 100.311 108.741 1.00 28.08  ? 328 ARG A C   1 
ATOM   1939  O O   . ARG A 1 328 ? 113.099 100.042 109.637 1.00 25.13  ? 328 ARG A O   1 
ATOM   1940  C CB  . ARG A 1 328 ? 116.147 99.433  109.397 1.00 25.11  ? 328 ARG A CB  1 
ATOM   1941  C CG  . ARG A 1 328 ? 117.095 98.229  109.358 1.00 19.59  ? 328 ARG A CG  1 
ATOM   1942  C CD  . ARG A 1 328 ? 117.993 98.148  110.598 1.00 29.13  ? 328 ARG A CD  1 
ATOM   1943  N NE  . ARG A 1 328 ? 117.245 97.774  111.812 1.00 24.99  ? 328 ARG A NE  1 
ATOM   1944  C CZ  . ARG A 1 328 ? 117.118 96.567  112.313 1.00 25.27  ? 328 ARG A CZ  1 
ATOM   1945  N NH1 . ARG A 1 328 ? 116.297 96.348  113.285 1.00 24.88  ? 328 ARG A NH1 1 
ATOM   1946  N NH2 . ARG A 1 328 ? 117.770 95.549  111.846 1.00 31.15  ? 328 ARG A NH2 1 
ATOM   1947  N N   . LYS A 1 329 ? 113.790 101.431 108.031 1.00 28.15  ? 329 LYS A N   1 
ATOM   1948  C CA  . LYS A 1 329 ? 112.715 102.418 108.124 1.00 25.81  ? 329 LYS A CA  1 
ATOM   1949  C C   . LYS A 1 329 ? 111.857 102.336 106.866 1.00 24.79  ? 329 LYS A C   1 
ATOM   1950  O O   . LYS A 1 329 ? 112.390 102.311 105.768 1.00 33.60  ? 329 LYS A O   1 
ATOM   1951  C CB  . LYS A 1 329 ? 113.350 103.799 108.306 1.00 22.68  ? 329 LYS A CB  1 
ATOM   1952  C CG  . LYS A 1 329 ? 112.334 104.929 108.478 1.00 18.43  ? 329 LYS A CG  1 
ATOM   1953  C CD  . LYS A 1 329 ? 113.059 106.270 108.527 1.00 23.14  ? 329 LYS A CD  1 
ATOM   1954  C CE  . LYS A 1 329 ? 112.060 107.409 108.713 1.00 24.53  ? 329 LYS A CE  1 
ATOM   1955  N NZ  . LYS A 1 329 ? 112.740 108.719 108.812 1.00 28.35  ? 329 LYS A NZ  1 
ATOM   1956  N N   . PHE A 1 330 ? 110.541 102.320 107.019 1.00 25.43  ? 330 PHE A N   1 
ATOM   1957  C CA  . PHE A 1 330 ? 109.573 102.343 105.928 1.00 20.80  ? 330 PHE A CA  1 
ATOM   1958  C C   . PHE A 1 330 ? 108.614 103.514 106.123 1.00 26.90  ? 330 PHE A C   1 
ATOM   1959  O O   . PHE A 1 330 ? 107.896 103.543 107.117 1.00 34.63  ? 330 PHE A O   1 
ATOM   1960  C CB  . PHE A 1 330 ? 108.809 101.012 105.890 1.00 24.02  ? 330 PHE A CB  1 
ATOM   1961  C CG  . PHE A 1 330 ? 109.695 99.786  105.819 1.00 35.48  ? 330 PHE A CG  1 
ATOM   1962  C CD1 . PHE A 1 330 ? 110.187 99.194  106.998 1.00 36.04  ? 330 PHE A CD1 1 
ATOM   1963  C CD2 . PHE A 1 330 ? 110.065 99.268  104.570 1.00 29.88  ? 330 PHE A CD2 1 
ATOM   1964  C CE1 . PHE A 1 330 ? 111.065 98.106  106.923 1.00 32.97  ? 330 PHE A CE1 1 
ATOM   1965  C CE2 . PHE A 1 330 ? 110.926 98.167  104.493 1.00 29.71  ? 330 PHE A CE2 1 
ATOM   1966  C CZ  . PHE A 1 330 ? 111.435 97.598  105.669 1.00 33.65  ? 330 PHE A CZ  1 
ATOM   1967  N N   . THR A 1 331 ? 108.547 104.470 105.205 1.00 37.38  ? 331 THR A N   1 
ATOM   1968  C CA  . THR A 1 331 ? 107.500 105.501 105.247 1.00 27.60  ? 331 THR A CA  1 
ATOM   1969  C C   . THR A 1 331 ? 106.126 104.872 105.019 1.00 26.87  ? 331 THR A C   1 
ATOM   1970  O O   . THR A 1 331 ? 105.925 104.099 104.088 1.00 35.26  ? 331 THR A O   1 
ATOM   1971  C CB  . THR A 1 331 ? 107.787 106.656 104.284 1.00 30.41  ? 331 THR A CB  1 
ATOM   1972  O OG1 . THR A 1 331 ? 106.880 107.692 104.551 1.00 30.29  ? 331 THR A OG1 1 
ATOM   1973  C CG2 . THR A 1 331 ? 107.643 106.329 102.800 1.00 39.58  ? 331 THR A CG2 1 
ATOM   1974  N N   . GLU A 1 332 ? 105.174 105.153 105.897 1.00 33.92  ? 332 GLU A N   1 
ATOM   1975  C CA  . GLU A 1 332 ? 103.815 104.628 105.824 1.00 32.38  ? 332 GLU A CA  1 
ATOM   1976  C C   . GLU A 1 332 ? 102.876 105.623 105.138 1.00 34.65  ? 332 GLU A C   1 
ATOM   1977  O O   . GLU A 1 332 ? 102.139 105.253 104.227 1.00 41.90  ? 332 GLU A O   1 
ATOM   1978  C CB  . GLU A 1 332 ? 103.347 104.279 107.237 1.00 32.51  ? 332 GLU A CB  1 
ATOM   1979  C CG  . GLU A 1 332 ? 102.024 103.512 107.215 1.00 37.65  ? 332 GLU A CG  1 
ATOM   1980  C CD  . GLU A 1 332 ? 101.669 102.977 108.602 1.00 45.11  ? 332 GLU A CD  1 
ATOM   1981  O OE1 . GLU A 1 332 ? 101.865 103.700 109.595 1.00 41.83  ? 332 GLU A OE1 1 
ATOM   1982  O OE2 . GLU A 1 332 ? 101.157 101.838 108.720 1.00 48.48  ? 332 GLU A OE2 1 
ATOM   1983  N N   . TRP A 1 333 ? 102.952 106.895 105.529 1.00 34.79  ? 333 TRP A N   1 
ATOM   1984  C CA  . TRP A 1 333 ? 102.379 108.030 104.807 1.00 30.29  ? 333 TRP A CA  1 
ATOM   1985  C C   . TRP A 1 333 ? 103.089 109.334 105.174 1.00 30.89  ? 333 TRP A C   1 
ATOM   1986  O O   . TRP A 1 333 ? 103.724 109.452 106.220 1.00 35.80  ? 333 TRP A O   1 
ATOM   1987  C CB  . TRP A 1 333 ? 100.863 108.134 105.033 1.00 26.23  ? 333 TRP A CB  1 
ATOM   1988  C CG  . TRP A 1 333 ? 100.361 108.288 106.435 1.00 28.35  ? 333 TRP A CG  1 
ATOM   1989  C CD1 . TRP A 1 333 ? 99.918  107.274 107.207 1.00 30.22  ? 333 TRP A CD1 1 
ATOM   1990  C CD2 . TRP A 1 333 ? 100.186 109.500 107.232 1.00 33.81  ? 333 TRP A CD2 1 
ATOM   1991  N NE1 . TRP A 1 333 ? 99.463  107.770 108.406 1.00 33.66  ? 333 TRP A NE1 1 
ATOM   1992  C CE2 . TRP A 1 333 ? 99.559  109.139 108.461 1.00 32.15  ? 333 TRP A CE2 1 
ATOM   1993  C CE3 . TRP A 1 333 ? 100.462 110.871 107.044 1.00 33.16  ? 333 TRP A CE3 1 
ATOM   1994  C CZ2 . TRP A 1 333 ? 99.193  110.081 109.428 1.00 27.43  ? 333 TRP A CZ2 1 
ATOM   1995  C CZ3 . TRP A 1 333 ? 100.147 111.819 108.033 1.00 32.88  ? 333 TRP A CZ3 1 
ATOM   1996  C CH2 . TRP A 1 333 ? 99.497  111.429 109.215 1.00 32.98  ? 333 TRP A CH2 1 
ATOM   1997  N N   . CYS A 1 334 ? 102.987 110.329 104.300 1.00 39.47  ? 334 CYS A N   1 
ATOM   1998  C CA  . CYS A 1 334 ? 103.542 111.660 104.494 1.00 33.46  ? 334 CYS A CA  1 
ATOM   1999  C C   . CYS A 1 334 ? 102.520 112.704 104.031 1.00 35.78  ? 334 CYS A C   1 
ATOM   2000  O O   . CYS A 1 334 ? 101.997 112.605 102.925 1.00 44.07  ? 334 CYS A O   1 
ATOM   2001  C CB  . CYS A 1 334 ? 104.868 111.706 103.727 1.00 33.36  ? 334 CYS A CB  1 
ATOM   2002  S SG  . CYS A 1 334 ? 105.711 113.282 103.963 1.00 58.05  ? 334 CYS A SG  1 
ATOM   2003  N N   . TYR A 1 335 ? 102.221 113.703 104.856 1.00 30.38  ? 335 TYR A N   1 
ATOM   2004  C CA  . TYR A 1 335 ? 101.206 114.717 104.572 1.00 30.98  ? 335 TYR A CA  1 
ATOM   2005  C C   . TYR A 1 335 ? 101.612 116.037 105.227 1.00 34.11  ? 335 TYR A C   1 
ATOM   2006  O O   . TYR A 1 335 ? 101.611 116.177 106.449 1.00 36.00  ? 335 TYR A O   1 
ATOM   2007  C CB  . TYR A 1 335 ? 99.827  114.229 105.034 1.00 34.36  ? 335 TYR A CB  1 
ATOM   2008  C CG  . TYR A 1 335 ? 98.670  115.136 104.673 1.00 33.63  ? 335 TYR A CG  1 
ATOM   2009  C CD1 . TYR A 1 335 ? 98.292  116.175 105.537 1.00 34.68  ? 335 TYR A CD1 1 
ATOM   2010  C CD2 . TYR A 1 335 ? 97.948  114.925 103.487 1.00 34.02  ? 335 TYR A CD2 1 
ATOM   2011  C CE1 . TYR A 1 335 ? 97.217  117.024 105.203 1.00 29.85  ? 335 TYR A CE1 1 
ATOM   2012  C CE2 . TYR A 1 335 ? 96.886  115.781 103.138 1.00 35.97  ? 335 TYR A CE2 1 
ATOM   2013  C CZ  . TYR A 1 335 ? 96.520  116.833 103.997 1.00 36.22  ? 335 TYR A CZ  1 
ATOM   2014  O OH  . TYR A 1 335 ? 95.490  117.651 103.668 1.00 36.21  ? 335 TYR A OH  1 
ATOM   2015  N N   . GLY A 1 336 ? 102.017 117.009 104.418 1.00 37.97  ? 336 GLY A N   1 
ATOM   2016  C CA  . GLY A 1 336 ? 102.569 118.262 104.904 1.00 29.88  ? 336 GLY A CA  1 
ATOM   2017  C C   . GLY A 1 336 ? 103.825 118.029 105.753 1.00 31.06  ? 336 GLY A C   1 
ATOM   2018  O O   . GLY A 1 336 ? 104.676 117.224 105.372 1.00 40.15  ? 336 GLY A O   1 
ATOM   2019  N N   . PRO A 1 337 ? 103.960 118.682 106.918 1.00 32.92  ? 337 PRO A N   1 
ATOM   2020  C CA  . PRO A 1 337 ? 105.115 118.537 107.801 1.00 32.92  ? 337 PRO A CA  1 
ATOM   2021  C C   . PRO A 1 337 ? 105.164 117.199 108.552 1.00 35.80  ? 337 PRO A C   1 
ATOM   2022  O O   . PRO A 1 337 ? 106.104 116.973 109.305 1.00 36.84  ? 337 PRO A O   1 
ATOM   2023  C CB  . PRO A 1 337 ? 105.015 119.725 108.753 1.00 29.27  ? 337 PRO A CB  1 
ATOM   2024  C CG  . PRO A 1 337 ? 103.510 119.945 108.869 1.00 31.07  ? 337 PRO A CG  1 
ATOM   2025  C CD  . PRO A 1 337 ? 103.009 119.619 107.476 1.00 30.80  ? 337 PRO A CD  1 
ATOM   2026  N N   . VAL A 1 338 ? 104.173 116.320 108.380 1.00 36.91  ? 338 VAL A N   1 
ATOM   2027  C CA  . VAL A 1 338 ? 104.039 115.056 109.108 1.00 32.08  ? 338 VAL A CA  1 
ATOM   2028  C C   . VAL A 1 338 ? 104.511 113.877 108.257 1.00 34.98  ? 338 VAL A C   1 
ATOM   2029  O O   . VAL A 1 338 ? 104.005 113.651 107.161 1.00 35.76  ? 338 VAL A O   1 
ATOM   2030  C CB  . VAL A 1 338 ? 102.584 114.829 109.560 1.00 36.95  ? 338 VAL A CB  1 
ATOM   2031  C CG1 . VAL A 1 338 ? 102.478 113.611 110.485 1.00 32.48  ? 338 VAL A CG1 1 
ATOM   2032  C CG2 . VAL A 1 338 ? 102.020 116.055 110.289 1.00 33.46  ? 338 VAL A CG2 1 
ATOM   2033  N N   . ARG A 1 339 ? 105.449 113.093 108.791 1.00 35.48  ? 339 ARG A N   1 
ATOM   2034  C CA  . ARG A 1 339 ? 105.886 111.788 108.272 1.00 27.93  ? 339 ARG A CA  1 
ATOM   2035  C C   . ARG A 1 339 ? 105.541 110.710 109.281 1.00 27.60  ? 339 ARG A C   1 
ATOM   2036  O O   . ARG A 1 339 ? 105.994 110.770 110.416 1.00 33.31  ? 339 ARG A O   1 
ATOM   2037  C CB  . ARG A 1 339 ? 107.398 111.804 108.013 1.00 34.42  ? 339 ARG A CB  1 
ATOM   2038  C CG  . ARG A 1 339 ? 107.750 112.576 106.746 1.00 37.98  ? 339 ARG A CG  1 
ATOM   2039  C CD  . ARG A 1 339 ? 109.261 112.625 106.521 1.00 36.89  ? 339 ARG A CD  1 
ATOM   2040  N NE  . ARG A 1 339 ? 109.587 113.267 105.234 1.00 40.28  ? 339 ARG A NE  1 
ATOM   2041  C CZ  . ARG A 1 339 ? 109.682 112.688 104.056 1.00 46.29  ? 339 ARG A CZ  1 
ATOM   2042  N NH1 . ARG A 1 339 ? 109.953 113.394 102.998 1.00 44.76  ? 339 ARG A NH1 1 
ATOM   2043  N NH2 . ARG A 1 339 ? 109.529 111.404 103.891 1.00 44.45  ? 339 ARG A NH2 1 
ATOM   2044  N N   . VAL A 1 340 ? 104.802 109.690 108.877 1.00 27.34  ? 340 VAL A N   1 
ATOM   2045  C CA  . VAL A 1 340 ? 104.589 108.491 109.688 1.00 26.58  ? 340 VAL A CA  1 
ATOM   2046  C C   . VAL A 1 340 ? 105.411 107.357 109.104 1.00 28.65  ? 340 VAL A C   1 
ATOM   2047  O O   . VAL A 1 340 ? 105.293 107.048 107.926 1.00 28.79  ? 340 VAL A O   1 
ATOM   2048  C CB  . VAL A 1 340 ? 103.100 108.149 109.804 1.00 25.84  ? 340 VAL A CB  1 
ATOM   2049  C CG1 . VAL A 1 340 ? 102.891 106.901 110.661 1.00 24.74  ? 340 VAL A CG1 1 
ATOM   2050  C CG2 . VAL A 1 340 ? 102.367 109.320 110.454 1.00 24.82  ? 340 VAL A CG2 1 
ATOM   2051  N N   . SER A 1 341 ? 106.272 106.754 109.915 1.00 32.48  ? 341 SER A N   1 
ATOM   2052  C CA  . SER A 1 341 ? 107.179 105.684 109.501 1.00 25.77  ? 341 SER A CA  1 
ATOM   2053  C C   . SER A 1 341 ? 107.049 104.468 110.395 1.00 24.67  ? 341 SER A C   1 
ATOM   2054  O O   . SER A 1 341 ? 106.841 104.594 111.593 1.00 27.60  ? 341 SER A O   1 
ATOM   2055  C CB  . SER A 1 341 ? 108.632 106.147 109.524 1.00 30.97  ? 341 SER A CB  1 
ATOM   2056  O OG  . SER A 1 341 ? 108.828 107.247 108.666 1.00 35.52  ? 341 SER A OG  1 
ATOM   2057  N N   . LEU A 1 342 ? 107.257 103.291 109.827 1.00 25.72  ? 342 LEU A N   1 
ATOM   2058  C CA  . LEU A 1 342 ? 107.499 102.053 110.554 1.00 25.86  ? 342 LEU A CA  1 
ATOM   2059  C C   . LEU A 1 342 ? 109.006 101.810 110.641 1.00 22.68  ? 342 LEU A C   1 
ATOM   2060  O O   . LEU A 1 342 ? 109.689 101.817 109.625 1.00 25.10  ? 342 LEU A O   1 
ATOM   2061  C CB  . LEU A 1 342 ? 106.820 100.894 109.814 1.00 29.61  ? 342 LEU A CB  1 
ATOM   2062  C CG  . LEU A 1 342 ? 105.288 100.949 109.770 1.00 27.78  ? 342 LEU A CG  1 
ATOM   2063  C CD1 . LEU A 1 342 ? 104.768 99.795  108.915 1.00 28.52  ? 342 LEU A CD1 1 
ATOM   2064  C CD2 . LEU A 1 342 ? 104.676 100.843 111.161 1.00 24.13  ? 342 LEU A CD2 1 
ATOM   2065  N N   . TYR A 1 343 ? 109.529 101.572 111.835 1.00 30.00  ? 343 TYR A N   1 
ATOM   2066  C CA  . TYR A 1 343 ? 110.911 101.151 112.058 1.00 20.08  ? 343 TYR A CA  1 
ATOM   2067  C C   . TYR A 1 343 ? 110.983 99.691  112.490 1.00 22.39  ? 343 TYR A C   1 
ATOM   2068  O O   . TYR A 1 343 ? 110.296 99.282  113.417 1.00 27.10  ? 343 TYR A O   1 
ATOM   2069  C CB  . TYR A 1 343 ? 111.567 102.013 113.127 1.00 15.35  ? 343 TYR A CB  1 
ATOM   2070  C CG  . TYR A 1 343 ? 111.868 103.436 112.726 1.00 17.42  ? 343 TYR A CG  1 
ATOM   2071  C CD1 . TYR A 1 343 ? 110.913 104.450 112.901 1.00 16.41  ? 343 TYR A CD1 1 
ATOM   2072  C CD2 . TYR A 1 343 ? 113.147 103.748 112.240 1.00 14.89  ? 343 TYR A CD2 1 
ATOM   2073  C CE1 . TYR A 1 343 ? 111.255 105.788 112.628 1.00 12.58  ? 343 TYR A CE1 1 
ATOM   2074  C CE2 . TYR A 1 343 ? 113.488 105.079 111.981 1.00 14.83  ? 343 TYR A CE2 1 
ATOM   2075  C CZ  . TYR A 1 343 ? 112.552 106.105 112.191 1.00 21.08  ? 343 TYR A CZ  1 
ATOM   2076  O OH  . TYR A 1 343 ? 112.911 107.390 111.952 1.00 32.08  ? 343 TYR A OH  1 
ATOM   2077  N N   . ASP A 1 344 ? 111.851 98.921  111.858 1.00 25.80  ? 344 ASP A N   1 
ATOM   2078  C CA  . ASP A 1 344 ? 112.169 97.535  112.185 1.00 27.02  ? 344 ASP A CA  1 
ATOM   2079  C C   . ASP A 1 344 ? 112.871 97.421  113.554 1.00 27.95  ? 344 ASP A C   1 
ATOM   2080  O O   . ASP A 1 344 ? 113.977 97.932  113.744 1.00 35.52  ? 344 ASP A O   1 
ATOM   2081  C CB  . ASP A 1 344 ? 113.033 97.021  111.026 1.00 22.53  ? 344 ASP A CB  1 
ATOM   2082  C CG  . ASP A 1 344 ? 113.503 95.574  111.125 1.00 30.51  ? 344 ASP A CG  1 
ATOM   2083  O OD1 . ASP A 1 344 ? 113.327 94.925  112.175 1.00 38.11  ? 344 ASP A OD1 1 
ATOM   2084  O OD2 . ASP A 1 344 ? 114.084 95.094  110.130 1.00 31.30  ? 344 ASP A OD2 1 
ATOM   2085  N N   . LEU A 1 345 ? 112.240 96.736  114.508 1.00 20.36  ? 345 LEU A N   1 
ATOM   2086  C CA  . LEU A 1 345 ? 112.754 96.532  115.865 1.00 21.61  ? 345 LEU A CA  1 
ATOM   2087  C C   . LEU A 1 345 ? 113.514 95.218  116.084 1.00 24.73  ? 345 LEU A C   1 
ATOM   2088  O O   . LEU A 1 345 ? 113.882 94.922  117.218 1.00 36.33  ? 345 LEU A O   1 
ATOM   2089  C CB  . LEU A 1 345 ? 111.596 96.637  116.871 1.00 28.45  ? 345 LEU A CB  1 
ATOM   2090  C CG  . LEU A 1 345 ? 110.949 98.015  117.039 1.00 25.07  ? 345 LEU A CG  1 
ATOM   2091  C CD1 . LEU A 1 345 ? 110.127 97.957  118.326 1.00 24.04  ? 345 LEU A CD1 1 
ATOM   2092  C CD2 . LEU A 1 345 ? 111.962 99.149  117.170 1.00 30.03  ? 345 LEU A CD2 1 
ATOM   2093  N N   . SER A 1 346 ? 113.759 94.417  115.048 1.00 30.17  ? 346 SER A N   1 
ATOM   2094  C CA  . SER A 1 346 ? 114.188 93.004  115.135 1.00 36.47  ? 346 SER A CA  1 
ATOM   2095  C C   . SER A 1 346 ? 115.289 92.679  116.160 1.00 43.13  ? 346 SER A C   1 
ATOM   2096  O O   . SER A 1 346 ? 115.112 91.784  116.988 1.00 46.70  ? 346 SER A O   1 
ATOM   2097  C CB  . SER A 1 346 ? 114.603 92.501  113.749 1.00 28.64  ? 346 SER A CB  1 
ATOM   2098  O OG  . SER A 1 346 ? 115.336 93.486  113.053 1.00 36.15  ? 346 SER A OG  1 
ATOM   2099  N N   . SER A 1 347 ? 116.402 93.411  116.144 1.00 28.09  ? 347 SER A N   1 
ATOM   2100  C CA  . SER A 1 347 ? 117.508 93.261  117.107 1.00 24.99  ? 347 SER A CA  1 
ATOM   2101  C C   . SER A 1 347 ? 117.619 94.419  118.112 1.00 28.30  ? 347 SER A C   1 
ATOM   2102  O O   . SER A 1 347 ? 118.617 94.562  118.817 1.00 27.09  ? 347 SER A O   1 
ATOM   2103  C CB  . SER A 1 347 ? 118.804 93.038  116.329 1.00 27.98  ? 347 SER A CB  1 
ATOM   2104  O OG  . SER A 1 347 ? 119.012 94.082  115.401 1.00 38.89  ? 347 SER A OG  1 
ATOM   2105  N N   . VAL A 1 348 ? 116.589 95.263  118.185 1.00 32.11  ? 348 VAL A N   1 
ATOM   2106  C CA  . VAL A 1 348 ? 116.549 96.500  118.967 1.00 26.66  ? 348 VAL A CA  1 
ATOM   2107  C C   . VAL A 1 348 ? 115.781 96.339  120.274 1.00 28.55  ? 348 VAL A C   1 
ATOM   2108  O O   . VAL A 1 348 ? 116.291 96.712  121.326 1.00 27.33  ? 348 VAL A O   1 
ATOM   2109  C CB  . VAL A 1 348 ? 116.010 97.668  118.123 1.00 29.12  ? 348 VAL A CB  1 
ATOM   2110  C CG1 . VAL A 1 348 ? 115.890 98.960  118.929 1.00 28.49  ? 348 VAL A CG1 1 
ATOM   2111  C CG2 . VAL A 1 348 ? 116.919 97.956  116.928 1.00 18.74  ? 348 VAL A CG2 1 
ATOM   2112  N N   . ASP A 1 349 ? 114.573 95.783  120.221 1.00 34.25  ? 349 ASP A N   1 
ATOM   2113  C CA  . ASP A 1 349 ? 113.695 95.653  121.385 1.00 35.97  ? 349 ASP A CA  1 
ATOM   2114  C C   . ASP A 1 349 ? 114.308 94.738  122.462 1.00 36.18  ? 349 ASP A C   1 
ATOM   2115  O O   . ASP A 1 349 ? 114.847 93.672  122.168 1.00 44.84  ? 349 ASP A O   1 
ATOM   2116  C CB  . ASP A 1 349 ? 112.316 95.168  120.920 1.00 34.90  ? 349 ASP A CB  1 
ATOM   2117  C CG  . ASP A 1 349 ? 111.245 95.137  122.019 1.00 44.47  ? 349 ASP A CG  1 
ATOM   2118  O OD1 . ASP A 1 349 ? 111.429 95.790  123.074 1.00 41.19  ? 349 ASP A OD1 1 
ATOM   2119  O OD2 . ASP A 1 349 ? 110.231 94.445  121.801 1.00 49.03  ? 349 ASP A OD2 1 
ATOM   2120  N N   . SER A 1 350 ? 114.209 95.147  123.723 1.00 33.59  ? 350 SER A N   1 
ATOM   2121  C CA  . SER A 1 350 ? 114.737 94.471  124.914 1.00 32.69  ? 350 SER A CA  1 
ATOM   2122  C C   . SER A 1 350 ? 114.003 93.181  125.306 1.00 36.35  ? 350 SER A C   1 
ATOM   2123  O O   . SER A 1 350 ? 114.411 92.504  126.250 1.00 39.80  ? 350 SER A O   1 
ATOM   2124  C CB  . SER A 1 350 ? 114.706 95.467  126.069 1.00 34.43  ? 350 SER A CB  1 
ATOM   2125  O OG  . SER A 1 350 ? 113.415 96.017  126.191 1.00 41.87  ? 350 SER A OG  1 
ATOM   2126  N N   . TRP A 1 351 ? 112.943 92.805  124.587 1.00 39.40  ? 351 TRP A N   1 
ATOM   2127  C CA  . TRP A 1 351 ? 112.323 91.482  124.671 1.00 39.52  ? 351 TRP A CA  1 
ATOM   2128  C C   . TRP A 1 351 ? 113.302 90.361  124.306 1.00 43.73  ? 351 TRP A C   1 
ATOM   2129  O O   . TRP A 1 351 ? 113.279 89.296  124.914 1.00 44.59  ? 351 TRP A O   1 
ATOM   2130  C CB  . TRP A 1 351 ? 111.103 91.466  123.747 1.00 41.65  ? 351 TRP A CB  1 
ATOM   2131  C CG  . TRP A 1 351 ? 110.442 90.139  123.559 1.00 46.52  ? 351 TRP A CG  1 
ATOM   2132  C CD1 . TRP A 1 351 ? 109.480 89.615  124.347 1.00 42.19  ? 351 TRP A CD1 1 
ATOM   2133  C CD2 . TRP A 1 351 ? 110.706 89.129  122.536 1.00 44.75  ? 351 TRP A CD2 1 
ATOM   2134  N NE1 . TRP A 1 351 ? 109.114 88.370  123.880 1.00 42.79  ? 351 TRP A NE1 1 
ATOM   2135  C CE2 . TRP A 1 351 ? 109.843 88.016  122.766 1.00 43.02  ? 351 TRP A CE2 1 
ATOM   2136  C CE3 . TRP A 1 351 ? 111.565 89.059  121.421 1.00 38.80  ? 351 TRP A CE3 1 
ATOM   2137  C CZ2 . TRP A 1 351 ? 109.851 86.881  121.947 1.00 42.38  ? 351 TRP A CZ2 1 
ATOM   2138  C CZ3 . TRP A 1 351 ? 111.591 87.919  120.601 1.00 43.16  ? 351 TRP A CZ3 1 
ATOM   2139  C CH2 . TRP A 1 351 ? 110.742 86.831  120.863 1.00 46.16  ? 351 TRP A CH2 1 
ATOM   2140  N N   . GLU A 1 352 ? 114.182 90.604  123.335 1.00 46.79  ? 352 GLU A N   1 
ATOM   2141  C CA  . GLU A 1 352 ? 115.229 89.672  122.918 1.00 41.40  ? 352 GLU A CA  1 
ATOM   2142  C C   . GLU A 1 352 ? 116.509 89.847  123.751 1.00 43.03  ? 352 GLU A C   1 
ATOM   2143  O O   . GLU A 1 352 ? 116.876 90.951  124.154 1.00 42.01  ? 352 GLU A O   1 
ATOM   2144  C CB  . GLU A 1 352 ? 115.470 89.863  121.409 1.00 45.07  ? 352 GLU A CB  1 
ATOM   2145  C CG  . GLU A 1 352 ? 116.502 88.952  120.741 1.00 46.36  ? 352 GLU A CG  1 
ATOM   2146  C CD  . GLU A 1 352 ? 116.204 87.452  120.891 1.00 53.21  ? 352 GLU A CD  1 
ATOM   2147  O OE1 . GLU A 1 352 ? 116.208 86.943  122.035 1.00 51.00  ? 352 GLU A OE1 1 
ATOM   2148  O OE2 . GLU A 1 352 ? 116.000 86.780  119.860 1.00 52.49  ? 352 GLU A OE2 1 
ATOM   2149  N N   . LYS A 1 353 ? 117.227 88.753  124.000 1.00 45.08  ? 353 LYS A N   1 
ATOM   2150  C CA  . LYS A 1 353 ? 118.515 88.767  124.704 1.00 46.63  ? 353 LYS A CA  1 
ATOM   2151  C C   . LYS A 1 353 ? 119.563 89.561  123.912 1.00 47.55  ? 353 LYS A C   1 
ATOM   2152  O O   . LYS A 1 353 ? 119.655 89.419  122.694 1.00 43.78  ? 353 LYS A O   1 
ATOM   2153  C CB  . LYS A 1 353 ? 118.959 87.313  124.934 1.00 46.56  ? 353 LYS A CB  1 
ATOM   2154  C CG  . LYS A 1 353 ? 120.224 87.193  125.786 1.00 49.58  ? 353 LYS A CG  1 
ATOM   2155  C CD  . LYS A 1 353 ? 120.670 85.744  125.933 1.00 49.77  ? 353 LYS A CD  1 
ATOM   2156  C CE  . LYS A 1 353 ? 121.988 85.651  126.685 1.00 51.18  ? 353 LYS A CE  1 
ATOM   2157  N NZ  . LYS A 1 353 ? 122.493 84.275  126.770 1.00 49.38  ? 353 LYS A NZ  1 
ATOM   2158  N N   . ASN A 1 354 ? 120.407 90.334  124.601 1.00 40.45  ? 354 ASN A N   1 
ATOM   2159  C CA  . ASN A 1 354 ? 121.555 91.033  124.010 1.00 34.00  ? 354 ASN A CA  1 
ATOM   2160  C C   . ASN A 1 354 ? 121.146 91.993  122.872 1.00 33.99  ? 354 ASN A C   1 
ATOM   2161  O O   . ASN A 1 354 ? 121.749 92.010  121.803 1.00 45.33  ? 354 ASN A O   1 
ATOM   2162  C CB  . ASN A 1 354 ? 122.628 89.988  123.632 1.00 39.77  ? 354 ASN A CB  1 
ATOM   2163  C CG  . ASN A 1 354 ? 123.972 90.590  123.262 1.00 46.37  ? 354 ASN A CG  1 
ATOM   2164  O OD1 . ASN A 1 354 ? 124.511 91.419  123.969 1.00 45.96  ? 354 ASN A OD1 1 
ATOM   2165  N ND2 . ASN A 1 354 ? 124.577 90.169  122.180 1.00 43.65  ? 354 ASN A ND2 1 
ATOM   2166  N N   . SER A 1 355 ? 120.058 92.739  123.057 1.00 29.65  ? 355 SER A N   1 
ATOM   2167  C CA  . SER A 1 355 ? 119.550 93.694  122.072 1.00 21.78  ? 355 SER A CA  1 
ATOM   2168  C C   . SER A 1 355 ? 120.372 94.981  122.045 1.00 19.27  ? 355 SER A C   1 
ATOM   2169  O O   . SER A 1 355 ? 121.174 95.244  122.937 1.00 28.48  ? 355 SER A O   1 
ATOM   2170  C CB  . SER A 1 355 ? 118.075 93.985  122.331 1.00 20.95  ? 355 SER A CB  1 
ATOM   2171  O OG  . SER A 1 355 ? 117.889 94.945  123.345 1.00 27.57  ? 355 SER A OG  1 
ATOM   2172  N N   . VAL A 1 356 ? 120.156 95.830  121.043 1.00 21.92  ? 356 VAL A N   1 
ATOM   2173  C CA  . VAL A 1 356 ? 120.800 97.154  120.961 1.00 18.73  ? 356 VAL A CA  1 
ATOM   2174  C C   . VAL A 1 356 ? 120.560 98.007  122.206 1.00 15.30  ? 356 VAL A C   1 
ATOM   2175  O O   . VAL A 1 356 ? 121.475 98.691  122.650 1.00 30.37  ? 356 VAL A O   1 
ATOM   2176  C CB  . VAL A 1 356 ? 120.342 97.865  119.681 1.00 25.48  ? 356 VAL A CB  1 
ATOM   2177  C CG1 . VAL A 1 356 ? 120.501 99.377  119.656 1.00 25.95  ? 356 VAL A CG1 1 
ATOM   2178  C CG2 . VAL A 1 356 ? 121.077 97.281  118.476 1.00 19.97  ? 356 VAL A CG2 1 
ATOM   2179  N N   . LEU A 1 357 ? 119.372 97.952  122.810 1.00 35.64  ? 357 LEU A N   1 
ATOM   2180  C CA  . LEU A 1 357 ? 119.084 98.680  124.046 1.00 19.10  ? 357 LEU A CA  1 
ATOM   2181  C C   . LEU A 1 357 ? 119.910 98.178  125.232 1.00 17.29  ? 357 LEU A C   1 
ATOM   2182  O O   . LEU A 1 357 ? 120.509 98.980  125.939 1.00 25.97  ? 357 LEU A O   1 
ATOM   2183  C CB  . LEU A 1 357 ? 117.588 98.577  124.359 1.00 22.65  ? 357 LEU A CB  1 
ATOM   2184  C CG  . LEU A 1 357 ? 116.661 99.361  123.421 1.00 23.00  ? 357 LEU A CG  1 
ATOM   2185  C CD1 . LEU A 1 357 ? 115.221 99.100  123.844 1.00 22.52  ? 357 LEU A CD1 1 
ATOM   2186  C CD2 . LEU A 1 357 ? 116.915 100.863 123.485 1.00 25.16  ? 357 LEU A CD2 1 
ATOM   2187  N N   . GLU A 1 358 ? 119.996 96.862  125.435 1.00 25.47  ? 358 GLU A N   1 
ATOM   2188  C CA  . GLU A 1 358 ? 120.846 96.269  126.469 1.00 20.32  ? 358 GLU A CA  1 
ATOM   2189  C C   . GLU A 1 358 ? 122.333 96.578  126.241 1.00 29.36  ? 358 GLU A C   1 
ATOM   2190  O O   . GLU A 1 358 ? 123.052 96.899  127.186 1.00 36.00  ? 358 GLU A O   1 
ATOM   2191  C CB  . GLU A 1 358 ? 120.566 94.759  126.554 1.00 26.23  ? 358 GLU A CB  1 
ATOM   2192  C CG  . GLU A 1 358 ? 121.453 94.077  127.602 1.00 35.82  ? 358 GLU A CG  1 
ATOM   2193  C CD  . GLU A 1 358 ? 120.904 92.744  128.126 1.00 45.71  ? 358 GLU A CD  1 
ATOM   2194  O OE1 . GLU A 1 358 ? 120.546 91.866  127.309 1.00 46.33  ? 358 GLU A OE1 1 
ATOM   2195  O OE2 . GLU A 1 358 ? 120.863 92.574  129.367 1.00 41.00  ? 358 GLU A OE2 1 
ATOM   2196  N N   . ILE A 1 359 ? 122.794 96.565  124.991 1.00 25.01  ? 359 ILE A N   1 
ATOM   2197  C CA  . ILE A 1 359 ? 124.165 96.919  124.628 1.00 24.21  ? 359 ILE A CA  1 
ATOM   2198  C C   . ILE A 1 359 ? 124.469 98.389  124.911 1.00 23.34  ? 359 ILE A C   1 
ATOM   2199  O O   . ILE A 1 359 ? 125.479 98.670  125.544 1.00 35.36  ? 359 ILE A O   1 
ATOM   2200  C CB  . ILE A 1 359 ? 124.464 96.533  123.168 1.00 23.54  ? 359 ILE A CB  1 
ATOM   2201  C CG1 . ILE A 1 359 ? 124.535 94.999  123.052 1.00 18.08  ? 359 ILE A CG1 1 
ATOM   2202  C CG2 . ILE A 1 359 ? 125.772 97.155  122.662 1.00 22.39  ? 359 ILE A CG2 1 
ATOM   2203  C CD1 . ILE A 1 359 ? 124.404 94.500  121.625 1.00 22.31  ? 359 ILE A CD1 1 
ATOM   2204  N N   . ILE A 1 360 ? 123.638 99.350  124.499 1.00 26.23  ? 360 ILE A N   1 
ATOM   2205  C CA  . ILE A 1 360 ? 123.891 100.773 124.782 1.00 23.61  ? 360 ILE A CA  1 
ATOM   2206  C C   . ILE A 1 360 ? 123.907 101.045 126.290 1.00 26.51  ? 360 ILE A C   1 
ATOM   2207  O O   . ILE A 1 360 ? 124.786 101.750 126.784 1.00 34.65  ? 360 ILE A O   1 
ATOM   2208  C CB  . ILE A 1 360 ? 122.872 101.686 124.068 1.00 28.36  ? 360 ILE A CB  1 
ATOM   2209  C CG1 . ILE A 1 360 ? 123.035 101.605 122.542 1.00 21.88  ? 360 ILE A CG1 1 
ATOM   2210  C CG2 . ILE A 1 360 ? 123.038 103.151 124.512 1.00 21.69  ? 360 ILE A CG2 1 
ATOM   2211  C CD1 . ILE A 1 360 ? 121.818 102.120 121.772 1.00 22.19  ? 360 ILE A CD1 1 
ATOM   2212  N N   . ALA A 1 361 ? 122.965 100.470 127.037 1.00 27.43  ? 361 ALA A N   1 
ATOM   2213  C CA  . ALA A 1 361 ? 122.863 100.687 128.469 1.00 15.71  ? 361 ALA A CA  1 
ATOM   2214  C C   . ALA A 1 361 ? 124.043 100.083 129.252 1.00 23.10  ? 361 ALA A C   1 
ATOM   2215  O O   . ALA A 1 361 ? 124.612 100.779 130.089 1.00 29.44  ? 361 ALA A O   1 
ATOM   2216  C CB  . ALA A 1 361 ? 121.515 100.148 128.932 1.00 19.33  ? 361 ALA A CB  1 
ATOM   2217  N N   . PHE A 1 362 ? 124.433 98.833  128.978 1.00 26.02  ? 362 PHE A N   1 
ATOM   2218  C CA  . PHE A 1 362 ? 125.315 98.068  129.866 1.00 15.26  ? 362 PHE A CA  1 
ATOM   2219  C C   . PHE A 1 362 ? 126.627 97.562  129.263 1.00 25.99  ? 362 PHE A C   1 
ATOM   2220  O O   . PHE A 1 362 ? 127.539 97.264  130.030 1.00 39.19  ? 362 PHE A O   1 
ATOM   2221  C CB  . PHE A 1 362 ? 124.526 96.891  130.453 1.00 20.23  ? 362 PHE A CB  1 
ATOM   2222  C CG  . PHE A 1 362 ? 123.251 97.295  131.158 1.00 25.61  ? 362 PHE A CG  1 
ATOM   2223  C CD1 . PHE A 1 362 ? 123.305 98.001  132.371 1.00 24.75  ? 362 PHE A CD1 1 
ATOM   2224  C CD2 . PHE A 1 362 ? 122.006 97.017  130.572 1.00 29.32  ? 362 PHE A CD2 1 
ATOM   2225  C CE1 . PHE A 1 362 ? 122.120 98.424  132.991 1.00 25.99  ? 362 PHE A CE1 1 
ATOM   2226  C CE2 . PHE A 1 362 ? 120.821 97.440  131.191 1.00 23.42  ? 362 PHE A CE2 1 
ATOM   2227  C CZ  . PHE A 1 362 ? 120.878 98.151  132.398 1.00 27.02  ? 362 PHE A CZ  1 
ATOM   2228  N N   . HIS A 1 363 ? 126.760 97.414  127.941 1.00 26.53  ? 363 HIS A N   1 
ATOM   2229  C CA  . HIS A 1 363 ? 127.965 96.835  127.320 1.00 26.29  ? 363 HIS A CA  1 
ATOM   2230  C C   . HIS A 1 363 ? 128.830 97.882  126.618 1.00 30.54  ? 363 HIS A C   1 
ATOM   2231  O O   . HIS A 1 363 ? 130.034 97.708  126.483 1.00 38.18  ? 363 HIS A O   1 
ATOM   2232  C CB  . HIS A 1 363 ? 127.584 95.737  126.329 1.00 22.45  ? 363 HIS A CB  1 
ATOM   2233  C CG  . HIS A 1 363 ? 126.716 94.623  126.851 1.00 25.72  ? 363 HIS A CG  1 
ATOM   2234  N ND1 . HIS A 1 363 ? 126.129 93.655  126.040 1.00 40.84  ? 363 HIS A ND1 1 
ATOM   2235  C CD2 . HIS A 1 363 ? 126.398 94.343  128.145 1.00 30.29  ? 363 HIS A CD2 1 
ATOM   2236  C CE1 . HIS A 1 363 ? 125.448 92.841  126.857 1.00 36.77  ? 363 HIS A CE1 1 
ATOM   2237  N NE2 . HIS A 1 363 ? 125.594 93.233  128.126 1.00 36.73  ? 363 HIS A NE2 1 
ATOM   2238  N N   . CYS A 1 364 ? 128.228 98.969  126.162 1.00 29.79  ? 364 CYS A N   1 
ATOM   2239  C CA  . CYS A 1 364 ? 128.925 100.107 125.595 1.00 26.62  ? 364 CYS A CA  1 
ATOM   2240  C C   . CYS A 1 364 ? 129.638 100.904 126.703 1.00 34.81  ? 364 CYS A C   1 
ATOM   2241  O O   . CYS A 1 364 ? 129.086 101.099 127.783 1.00 32.33  ? 364 CYS A O   1 
ATOM   2242  C CB  . CYS A 1 364 ? 127.901 100.938 124.817 1.00 24.75  ? 364 CYS A CB  1 
ATOM   2243  S SG  . CYS A 1 364 ? 128.722 102.286 123.951 1.00 25.19  ? 364 CYS A SG  1 
ATOM   2244  N N   . LYS A 1 365 ? 130.842 101.408 126.422 1.00 41.48  ? 365 LYS A N   1 
ATOM   2245  C CA  . LYS A 1 365 ? 131.613 102.301 127.307 1.00 35.42  ? 365 LYS A CA  1 
ATOM   2246  C C   . LYS A 1 365 ? 132.060 103.608 126.651 1.00 34.83  ? 365 LYS A C   1 
ATOM   2247  O O   . LYS A 1 365 ? 132.929 104.306 127.163 1.00 44.31  ? 365 LYS A O   1 
ATOM   2248  C CB  . LYS A 1 365 ? 132.732 101.517 128.006 1.00 41.38  ? 365 LYS A CB  1 
ATOM   2249  C CG  . LYS A 1 365 ? 133.808 100.965 127.069 1.00 41.92  ? 365 LYS A CG  1 
ATOM   2250  C CD  . LYS A 1 365 ? 134.849 100.179 127.869 1.00 42.97  ? 365 LYS A CD  1 
ATOM   2251  C CE  . LYS A 1 365 ? 135.950 99.649  126.953 1.00 44.51  ? 365 LYS A CE  1 
ATOM   2252  N NZ  . LYS A 1 365 ? 136.985 98.920  127.719 1.00 43.68  ? 365 LYS A NZ  1 
ATOM   2253  N N   . SER A 1 366 ? 131.455 103.948 125.520 1.00 34.77  ? 366 SER A N   1 
ATOM   2254  C CA  . SER A 1 366 ? 131.670 105.206 124.804 1.00 33.52  ? 366 SER A CA  1 
ATOM   2255  C C   . SER A 1 366 ? 131.007 106.394 125.520 1.00 28.32  ? 366 SER A C   1 
ATOM   2256  O O   . SER A 1 366 ? 129.924 106.226 126.081 1.00 35.10  ? 366 SER A O   1 
ATOM   2257  C CB  . SER A 1 366 ? 131.109 105.049 123.390 1.00 32.52  ? 366 SER A CB  1 
ATOM   2258  O OG  . SER A 1 366 ? 131.308 106.212 122.626 1.00 33.45  ? 366 SER A OG  1 
ATOM   2259  N N   . PRO A 1 367 ? 131.560 107.619 125.474 1.00 37.32  ? 367 PRO A N   1 
ATOM   2260  C CA  . PRO A 1 367 ? 130.929 108.800 126.072 1.00 37.80  ? 367 PRO A CA  1 
ATOM   2261  C C   . PRO A 1 367 ? 129.634 109.254 125.379 1.00 40.74  ? 367 PRO A C   1 
ATOM   2262  O O   . PRO A 1 367 ? 128.891 110.058 125.932 1.00 48.45  ? 367 PRO A O   1 
ATOM   2263  C CB  . PRO A 1 367 ? 132.001 109.888 126.020 1.00 41.59  ? 367 PRO A CB  1 
ATOM   2264  C CG  . PRO A 1 367 ? 132.877 109.483 124.842 1.00 38.19  ? 367 PRO A CG  1 
ATOM   2265  C CD  . PRO A 1 367 ? 132.865 107.963 124.930 1.00 39.45  ? 367 PRO A CD  1 
ATOM   2266  N N   . ASN A 1 368 ? 129.359 108.771 124.164 1.00 34.15  ? 368 ASN A N   1 
ATOM   2267  C CA  . ASN A 1 368 ? 128.194 109.156 123.360 1.00 34.84  ? 368 ASN A CA  1 
ATOM   2268  C C   . ASN A 1 368 ? 126.984 108.211 123.487 1.00 36.18  ? 368 ASN A C   1 
ATOM   2269  O O   . ASN A 1 368 ? 126.041 108.321 122.704 1.00 44.69  ? 368 ASN A O   1 
ATOM   2270  C CB  . ASN A 1 368 ? 128.630 109.417 121.903 1.00 39.74  ? 368 ASN A CB  1 
ATOM   2271  C CG  . ASN A 1 368 ? 129.130 108.198 121.163 1.00 38.85  ? 368 ASN A CG  1 
ATOM   2272  O OD1 . ASN A 1 368 ? 129.017 107.066 121.605 1.00 46.06  ? 368 ASN A OD1 1 
ATOM   2273  N ND2 . ASN A 1 368 ? 129.745 108.381 120.028 1.00 33.67  ? 368 ASN A ND2 1 
ATOM   2274  N N   . ARG A 1 369 ? 126.941 107.328 124.494 1.00 27.25  ? 369 ARG A N   1 
ATOM   2275  C CA  . ARG A 1 369 ? 125.771 106.480 124.807 1.00 29.07  ? 369 ARG A CA  1 
ATOM   2276  C C   . ARG A 1 369 ? 124.479 107.275 124.931 1.00 28.00  ? 369 ARG A C   1 
ATOM   2277  O O   . ARG A 1 369 ? 123.436 106.857 124.441 1.00 29.83  ? 369 ARG A O   1 
ATOM   2278  C CB  . ARG A 1 369 ? 126.019 105.718 126.117 1.00 28.58  ? 369 ARG A CB  1 
ATOM   2279  C CG  . ARG A 1 369 ? 126.943 104.526 125.904 1.00 28.78  ? 369 ARG A CG  1 
ATOM   2280  C CD  . ARG A 1 369 ? 127.572 104.040 127.206 1.00 33.15  ? 369 ARG A CD  1 
ATOM   2281  N NE  . ARG A 1 369 ? 126.586 103.569 128.197 1.00 33.56  ? 369 ARG A NE  1 
ATOM   2282  C CZ  . ARG A 1 369 ? 126.357 104.084 129.390 1.00 29.11  ? 369 ARG A CZ  1 
ATOM   2283  N NH1 . ARG A 1 369 ? 125.578 103.515 130.251 1.00 21.79  ? 369 ARG A NH1 1 
ATOM   2284  N NH2 . ARG A 1 369 ? 126.891 105.202 129.774 1.00 31.11  ? 369 ARG A NH2 1 
ATOM   2285  N N   . HIS A 1 370 ? 124.539 108.455 125.543 1.00 31.40  ? 370 HIS A N   1 
ATOM   2286  C CA  . HIS A 1 370 ? 123.370 109.307 125.738 1.00 28.29  ? 370 HIS A CA  1 
ATOM   2287  C C   . HIS A 1 370 ? 122.852 109.936 124.438 1.00 28.19  ? 370 HIS A C   1 
ATOM   2288  O O   . HIS A 1 370 ? 121.647 110.252 124.393 1.00 36.87  ? 370 HIS A O   1 
ATOM   2289  C CB  . HIS A 1 370 ? 123.692 110.403 126.764 1.00 27.88  ? 370 HIS A CB  1 
ATOM   2290  C CG  . HIS A 1 370 ? 124.688 111.402 126.278 1.00 28.58  ? 370 HIS A CG  1 
ATOM   2291  N ND1 . HIS A 1 370 ? 124.312 112.629 125.769 1.00 27.18  ? 370 HIS A ND1 1 
ATOM   2292  C CD2 . HIS A 1 370 ? 126.036 111.361 126.214 1.00 32.07  ? 370 HIS A CD2 1 
ATOM   2293  C CE1 . HIS A 1 370 ? 125.387 113.304 125.416 1.00 33.53  ? 370 HIS A CE1 1 
ATOM   2294  N NE2 . HIS A 1 370 ? 126.460 112.547 125.679 1.00 36.00  ? 370 HIS A NE2 1 
ATOM   2295  N N   . ARG A 1 371 ? 123.706 110.109 123.423 1.00 31.10  ? 371 ARG A N   1 
ATOM   2296  C CA  . ARG A 1 371 ? 123.296 110.532 122.079 1.00 29.03  ? 371 ARG A CA  1 
ATOM   2297  C C   . ARG A 1 371 ? 122.625 109.404 121.287 1.00 31.75  ? 371 ARG A C   1 
ATOM   2298  O O   . ARG A 1 371 ? 121.721 109.679 120.512 1.00 28.95  ? 371 ARG A O   1 
ATOM   2299  C CB  . ARG A 1 371 ? 124.508 111.107 121.330 1.00 28.97  ? 371 ARG A CB  1 
ATOM   2300  C CG  . ARG A 1 371 ? 124.951 112.478 121.844 1.00 27.08  ? 371 ARG A CG  1 
ATOM   2301  C CD  . ARG A 1 371 ? 126.361 112.895 121.394 1.00 38.21  ? 371 ARG A CD  1 
ATOM   2302  N NE  . ARG A 1 371 ? 126.687 112.647 119.968 1.00 38.63  ? 371 ARG A NE  1 
ATOM   2303  C CZ  . ARG A 1 371 ? 126.190 113.236 118.895 1.00 38.70  ? 371 ARG A CZ  1 
ATOM   2304  N NH1 . ARG A 1 371 ? 126.688 112.993 117.723 1.00 36.80  ? 371 ARG A NH1 1 
ATOM   2305  N NH2 . ARG A 1 371 ? 125.203 114.076 118.952 1.00 37.65  ? 371 ARG A NH2 1 
ATOM   2306  N N   . MET A 1 372 ? 123.007 108.143 121.495 1.00 30.92  ? 372 MET A N   1 
ATOM   2307  C CA  . MET A 1 372 ? 122.378 106.993 120.834 1.00 20.81  ? 372 MET A CA  1 
ATOM   2308  C C   . MET A 1 372 ? 120.954 106.689 121.315 1.00 29.09  ? 372 MET A C   1 
ATOM   2309  O O   . MET A 1 372 ? 120.109 106.339 120.498 1.00 40.22  ? 372 MET A O   1 
ATOM   2310  C CB  . MET A 1 372 ? 123.245 105.739 120.968 1.00 20.21  ? 372 MET A CB  1 
ATOM   2311  C CG  . MET A 1 372 ? 124.522 105.844 120.139 1.00 34.13  ? 372 MET A CG  1 
ATOM   2312  S SD  . MET A 1 372 ? 125.464 104.312 119.985 1.00 47.10  ? 372 MET A SD  1 
ATOM   2313  C CE  . MET A 1 372 ? 126.132 104.188 121.660 1.00 27.45  ? 372 MET A CE  1 
ATOM   2314  N N   . VAL A 1 373 ? 120.640 106.834 122.607 1.00 27.91  ? 373 VAL A N   1 
ATOM   2315  C CA  . VAL A 1 373 ? 119.294 106.519 123.136 1.00 24.47  ? 373 VAL A CA  1 
ATOM   2316  C C   . VAL A 1 373 ? 118.210 107.518 122.720 1.00 27.27  ? 373 VAL A C   1 
ATOM   2317  O O   . VAL A 1 373 ? 117.030 107.216 122.850 1.00 33.42  ? 373 VAL A O   1 
ATOM   2318  C CB  . VAL A 1 373 ? 119.264 106.342 124.668 1.00 31.43  ? 373 VAL A CB  1 
ATOM   2319  C CG1 . VAL A 1 373 ? 120.159 105.199 125.121 1.00 27.63  ? 373 VAL A CG1 1 
ATOM   2320  C CG2 . VAL A 1 373 ? 119.634 107.606 125.433 1.00 19.54  ? 373 VAL A CG2 1 
ATOM   2321  N N   . VAL A 1 374 ? 118.587 108.694 122.215 1.00 21.51  ? 374 VAL A N   1 
ATOM   2322  C CA  . VAL A 1 374 ? 117.654 109.745 121.778 1.00 18.12  ? 374 VAL A CA  1 
ATOM   2323  C C   . VAL A 1 374 ? 117.424 109.772 120.260 1.00 23.25  ? 374 VAL A C   1 
ATOM   2324  O O   . VAL A 1 374 ? 116.756 110.670 119.758 1.00 31.19  ? 374 VAL A O   1 
ATOM   2325  C CB  . VAL A 1 374 ? 118.022 111.127 122.360 1.00 23.21  ? 374 VAL A CB  1 
ATOM   2326  C CG1 . VAL A 1 374 ? 118.036 111.102 123.889 1.00 29.00  ? 374 VAL A CG1 1 
ATOM   2327  C CG2 . VAL A 1 374 ? 119.366 111.653 121.872 1.00 23.29  ? 374 VAL A CG2 1 
ATOM   2328  N N   . LEU A 1 375 ? 117.938 108.789 119.515 1.00 25.16  ? 375 LEU A N   1 
ATOM   2329  C CA  . LEU A 1 375 ? 117.646 108.593 118.090 1.00 26.60  ? 375 LEU A CA  1 
ATOM   2330  C C   . LEU A 1 375 ? 116.280 107.920 117.888 1.00 27.96  ? 375 LEU A C   1 
ATOM   2331  O O   . LEU A 1 375 ? 115.877 107.105 118.706 1.00 30.74  ? 375 LEU A O   1 
ATOM   2332  C CB  . LEU A 1 375 ? 118.758 107.733 117.464 1.00 28.46  ? 375 LEU A CB  1 
ATOM   2333  C CG  . LEU A 1 375 ? 120.178 108.297 117.596 1.00 23.47  ? 375 LEU A CG  1 
ATOM   2334  C CD1 . LEU A 1 375 ? 121.166 107.343 116.952 1.00 23.02  ? 375 LEU A CD1 1 
ATOM   2335  C CD2 . LEU A 1 375 ? 120.326 109.662 116.941 1.00 26.31  ? 375 LEU A CD2 1 
ATOM   2336  N N   . GLU A 1 376 ? 115.573 108.165 116.784 1.00 31.53  ? 376 GLU A N   1 
ATOM   2337  C CA  . GLU A 1 376 ? 114.469 107.280 116.372 1.00 32.11  ? 376 GLU A CA  1 
ATOM   2338  C C   . GLU A 1 376 ? 115.006 105.920 115.889 1.00 26.50  ? 376 GLU A C   1 
ATOM   2339  O O   . GLU A 1 376 ? 116.045 105.896 115.226 1.00 34.91  ? 376 GLU A O   1 
ATOM   2340  C CB  . GLU A 1 376 ? 113.618 107.908 115.261 1.00 32.34  ? 376 GLU A CB  1 
ATOM   2341  C CG  . GLU A 1 376 ? 112.813 109.126 115.718 1.00 34.25  ? 376 GLU A CG  1 
ATOM   2342  C CD  . GLU A 1 376 ? 112.019 109.804 114.575 1.00 46.17  ? 376 GLU A CD  1 
ATOM   2343  O OE1 . GLU A 1 376 ? 111.824 109.190 113.499 1.00 44.27  ? 376 GLU A OE1 1 
ATOM   2344  O OE2 . GLU A 1 376 ? 111.592 110.962 114.773 1.00 46.32  ? 376 GLU A OE2 1 
ATOM   2345  N N   . PRO A 1 377 ? 114.318 104.791 116.156 1.00 22.39  ? 377 PRO A N   1 
ATOM   2346  C CA  . PRO A 1 377 ? 113.082 104.663 116.931 1.00 21.06  ? 377 PRO A CA  1 
ATOM   2347  C C   . PRO A 1 377 ? 113.332 104.477 118.442 1.00 24.64  ? 377 PRO A C   1 
ATOM   2348  O O   . PRO A 1 377 ? 112.359 104.271 119.144 1.00 28.92  ? 377 PRO A O   1 
ATOM   2349  C CB  . PRO A 1 377 ? 112.471 103.351 116.442 1.00 21.74  ? 377 PRO A CB  1 
ATOM   2350  C CG  . PRO A 1 377 ? 113.697 102.488 116.173 1.00 27.01  ? 377 PRO A CG  1 
ATOM   2351  C CD  . PRO A 1 377 ? 114.700 103.494 115.620 1.00 15.73  ? 377 PRO A CD  1 
ATOM   2352  N N   . LEU A 1 378 ? 114.586 104.558 118.915 1.00 30.89  ? 378 LEU A N   1 
ATOM   2353  C CA  . LEU A 1 378 ? 114.927 104.278 120.350 1.00 23.66  ? 378 LEU A CA  1 
ATOM   2354  C C   . LEU A 1 378 ? 114.285 105.299 121.300 1.00 28.91  ? 378 LEU A C   1 
ATOM   2355  O O   . LEU A 1 378 ? 113.782 104.902 122.342 1.00 35.48  ? 378 LEU A O   1 
ATOM   2356  C CB  . LEU A 1 378 ? 116.452 104.287 120.506 1.00 26.44  ? 378 LEU A CB  1 
ATOM   2357  C CG  . LEU A 1 378 ? 117.169 102.997 120.110 1.00 29.37  ? 378 LEU A CG  1 
ATOM   2358  C CD1 . LEU A 1 378 ? 116.923 102.658 118.648 1.00 26.46  ? 378 LEU A CD1 1 
ATOM   2359  C CD2 . LEU A 1 378 ? 118.662 103.104 120.385 1.00 29.92  ? 378 LEU A CD2 1 
ATOM   2360  N N   . ASN A 1 379 ? 114.232 106.577 120.940 1.00 27.56  ? 379 ASN A N   1 
ATOM   2361  C CA  . ASN A 1 379 ? 113.625 107.634 121.736 1.00 13.97  ? 379 ASN A CA  1 
ATOM   2362  C C   . ASN A 1 379 ? 112.152 107.349 122.080 1.00 19.97  ? 379 ASN A C   1 
ATOM   2363  O O   . ASN A 1 379 ? 111.792 107.278 123.250 1.00 36.01  ? 379 ASN A O   1 
ATOM   2364  C CB  . ASN A 1 379 ? 113.793 108.951 120.970 1.00 20.00  ? 379 ASN A CB  1 
ATOM   2365  C CG  . ASN A 1 379 ? 113.376 110.161 121.783 1.00 33.20  ? 379 ASN A CG  1 
ATOM   2366  O OD1 . ASN A 1 379 ? 113.846 110.393 122.881 1.00 36.70  ? 379 ASN A OD1 1 
ATOM   2367  N ND2 . ASN A 1 379 ? 112.481 110.966 121.279 1.00 30.42  ? 379 ASN A ND2 1 
ATOM   2368  N N   . LYS A 1 380 ? 111.291 107.148 121.074 1.00 32.46  ? 380 LYS A N   1 
ATOM   2369  C CA  . LYS A 1 380 ? 109.865 106.868 121.286 1.00 24.60  ? 380 LYS A CA  1 
ATOM   2370  C C   . LYS A 1 380 ? 109.651 105.475 121.875 1.00 22.87  ? 380 LYS A C   1 
ATOM   2371  O O   . LYS A 1 380 ? 108.770 105.302 122.707 1.00 33.77  ? 380 LYS A O   1 
ATOM   2372  C CB  . LYS A 1 380 ? 109.062 107.106 119.989 1.00 27.43  ? 380 LYS A CB  1 
ATOM   2373  C CG  . LYS A 1 380 ? 107.547 106.956 120.247 1.00 36.01  ? 380 LYS A CG  1 
ATOM   2374  C CD  . LYS A 1 380 ? 106.665 106.864 119.001 1.00 32.56  ? 380 LYS A CD  1 
ATOM   2375  C CE  . LYS A 1 380 ? 105.243 106.502 119.459 1.00 35.04  ? 380 LYS A CE  1 
ATOM   2376  N NZ  . LYS A 1 380 ? 104.311 106.293 118.325 1.00 34.60  ? 380 LYS A NZ  1 
ATOM   2377  N N   . LEU A 1 381 ? 110.469 104.495 121.508 1.00 16.57  ? 381 LEU A N   1 
ATOM   2378  C CA  . LEU A 1 381 ? 110.409 103.148 122.071 1.00 19.42  ? 381 LEU A CA  1 
ATOM   2379  C C   . LEU A 1 381 ? 110.713 103.142 123.575 1.00 23.99  ? 381 LEU A C   1 
ATOM   2380  O O   . LEU A 1 381 ? 109.994 102.540 124.362 1.00 35.47  ? 381 LEU A O   1 
ATOM   2381  C CB  . LEU A 1 381 ? 111.384 102.268 121.273 1.00 25.64  ? 381 LEU A CB  1 
ATOM   2382  C CG  . LEU A 1 381 ? 111.441 100.804 121.718 1.00 30.04  ? 381 LEU A CG  1 
ATOM   2383  C CD1 . LEU A 1 381 ? 110.125 100.095 121.452 1.00 28.72  ? 381 LEU A CD1 1 
ATOM   2384  C CD2 . LEU A 1 381 ? 112.548 100.094 120.950 1.00 27.08  ? 381 LEU A CD2 1 
ATOM   2385  N N   . LEU A 1 382 ? 111.749 103.856 124.006 1.00 30.48  ? 382 LEU A N   1 
ATOM   2386  C CA  . LEU A 1 382 ? 112.082 104.021 125.417 1.00 18.83  ? 382 LEU A CA  1 
ATOM   2387  C C   . LEU A 1 382 ? 111.048 104.858 126.161 1.00 20.21  ? 382 LEU A C   1 
ATOM   2388  O O   . LEU A 1 382 ? 110.754 104.542 127.307 1.00 35.02  ? 382 LEU A O   1 
ATOM   2389  C CB  . LEU A 1 382 ? 113.488 104.615 125.552 1.00 20.59  ? 382 LEU A CB  1 
ATOM   2390  C CG  . LEU A 1 382 ? 114.603 103.601 125.254 1.00 19.70  ? 382 LEU A CG  1 
ATOM   2391  C CD1 . LEU A 1 382 ? 115.922 104.338 125.092 1.00 16.69  ? 382 LEU A CD1 1 
ATOM   2392  C CD2 . LEU A 1 382 ? 114.742 102.570 126.374 1.00 22.15  ? 382 LEU A CD2 1 
ATOM   2393  N N   . GLN A 1 383 ? 110.413 105.812 125.477 1.00 23.11  ? 383 GLN A N   1 
ATOM   2394  C CA  . GLN A 1 383 ? 109.315 106.575 126.132 1.00 16.96  ? 383 GLN A CA  1 
ATOM   2395  C C   . GLN A 1 383 ? 108.119 105.628 126.338 1.00 18.80  ? 383 GLN A C   1 
ATOM   2396  O O   . GLN A 1 383 ? 107.568 105.633 127.457 1.00 36.27  ? 383 GLN A O   1 
ATOM   2397  C CB  . GLN A 1 383 ? 109.016 107.852 125.336 1.00 20.50  ? 383 GLN A CB  1 
ATOM   2398  C CG  . GLN A 1 383 ? 108.061 108.805 126.067 1.00 27.15  ? 383 GLN A CG  1 
ATOM   2399  C CD  . GLN A 1 383 ? 108.583 109.206 127.424 1.00 34.10  ? 383 GLN A CD  1 
ATOM   2400  O OE1 . GLN A 1 383 ? 109.784 109.182 127.683 1.00 37.34  ? 383 GLN A OE1 1 
ATOM   2401  N NE2 . GLN A 1 383 ? 107.675 109.589 128.307 1.00 27.25  ? 383 GLN A NE2 1 
ATOM   2402  N N   . GLU A 1 384 ? 107.732 104.842 125.322 1.00 29.60  ? 384 GLU A N   1 
ATOM   2403  C CA  . GLU A 1 384 ? 106.673 103.843 125.467 1.00 29.50  ? 384 GLU A CA  1 
ATOM   2404  C C   . GLU A 1 384 ? 106.937 102.854 126.607 1.00 28.08  ? 384 GLU A C   1 
ATOM   2405  O O   . GLU A 1 384 ? 106.017 102.515 127.350 1.00 34.91  ? 384 GLU A O   1 
ATOM   2406  C CB  . GLU A 1 384 ? 106.516 103.074 124.144 1.00 32.49  ? 384 GLU A CB  1 
ATOM   2407  C CG  . GLU A 1 384 ? 105.645 103.820 123.125 1.00 33.51  ? 384 GLU A CG  1 
ATOM   2408  C CD  . GLU A 1 384 ? 104.141 103.702 123.395 1.00 44.15  ? 384 GLU A CD  1 
ATOM   2409  O OE1 . GLU A 1 384 ? 103.730 103.038 124.375 1.00 46.48  ? 384 GLU A OE1 1 
ATOM   2410  O OE2 . GLU A 1 384 ? 103.357 104.263 122.599 1.00 43.34  ? 384 GLU A OE2 1 
ATOM   2411  N N   . LYS A 1 385 ? 108.183 102.401 126.780 1.00 30.69  ? 385 LYS A N   1 
ATOM   2412  C CA  . LYS A 1 385 ? 108.583 101.556 127.907 1.00 22.34  ? 385 LYS A CA  1 
ATOM   2413  C C   . LYS A 1 385 ? 108.525 102.307 129.235 1.00 24.81  ? 385 LYS A C   1 
ATOM   2414  O O   . LYS A 1 385 ? 108.027 101.760 130.211 1.00 26.52  ? 385 LYS A O   1 
ATOM   2415  C CB  . LYS A 1 385 ? 109.984 100.993 127.668 1.00 24.31  ? 385 LYS A CB  1 
ATOM   2416  C CG  . LYS A 1 385 ? 110.037 99.936  126.565 1.00 22.06  ? 385 LYS A CG  1 
ATOM   2417  C CD  . LYS A 1 385 ? 111.474 99.517  126.247 1.00 23.09  ? 385 LYS A CD  1 
ATOM   2418  C CE  . LYS A 1 385 ? 111.545 98.522  125.089 1.00 25.88  ? 385 LYS A CE  1 
ATOM   2419  N NZ  . LYS A 1 385 ? 110.881 97.247  125.398 1.00 28.25  ? 385 LYS A NZ  1 
ATOM   2420  N N   . TRP A 1 386 ? 108.986 103.555 129.290 1.00 20.72  ? 386 TRP A N   1 
ATOM   2421  C CA  . TRP A 1 386 ? 108.886 104.388 130.490 1.00 13.26  ? 386 TRP A CA  1 
ATOM   2422  C C   . TRP A 1 386 ? 107.434 104.626 130.905 1.00 25.03  ? 386 TRP A C   1 
ATOM   2423  O O   . TRP A 1 386 ? 107.088 104.405 132.059 1.00 38.22  ? 386 TRP A O   1 
ATOM   2424  C CB  . TRP A 1 386 ? 109.609 105.727 130.306 1.00 23.45  ? 386 TRP A CB  1 
ATOM   2425  C CG  . TRP A 1 386 ? 109.519 106.606 131.520 1.00 22.59  ? 386 TRP A CG  1 
ATOM   2426  C CD1 . TRP A 1 386 ? 108.561 107.529 131.745 1.00 26.97  ? 386 TRP A CD1 1 
ATOM   2427  C CD2 . TRP A 1 386 ? 110.274 106.522 132.766 1.00 28.25  ? 386 TRP A CD2 1 
ATOM   2428  N NE1 . TRP A 1 386 ? 108.643 107.980 133.044 1.00 31.92  ? 386 TRP A NE1 1 
ATOM   2429  C CE2 . TRP A 1 386 ? 109.673 107.375 133.728 1.00 27.81  ? 386 TRP A CE2 1 
ATOM   2430  C CE3 . TRP A 1 386 ? 111.395 105.782 133.189 1.00 26.85  ? 386 TRP A CE3 1 
ATOM   2431  C CZ2 . TRP A 1 386 ? 110.148 107.480 135.044 1.00 23.15  ? 386 TRP A CZ2 1 
ATOM   2432  C CZ3 . TRP A 1 386 ? 111.875 105.861 134.506 1.00 19.05  ? 386 TRP A CZ3 1 
ATOM   2433  C CH2 . TRP A 1 386 ? 111.257 106.714 135.433 1.00 26.45  ? 386 TRP A CH2 1 
ATOM   2434  N N   . ASP A 1 387 ? 106.558 105.019 129.989 1.00 29.94  ? 387 ASP A N   1 
ATOM   2435  C CA  . ASP A 1 387 ? 105.162 105.329 130.293 1.00 26.01  ? 387 ASP A CA  1 
ATOM   2436  C C   . ASP A 1 387 ? 104.386 104.136 130.877 1.00 28.46  ? 387 ASP A C   1 
ATOM   2437  O O   . ASP A 1 387 ? 103.512 104.333 131.711 1.00 38.32  ? 387 ASP A O   1 
ATOM   2438  C CB  . ASP A 1 387 ? 104.455 105.857 129.038 1.00 28.09  ? 387 ASP A CB  1 
ATOM   2439  C CG  . ASP A 1 387 ? 104.926 107.235 128.553 1.00 35.08  ? 387 ASP A CG  1 
ATOM   2440  O OD1 . ASP A 1 387 ? 105.663 107.938 129.277 1.00 37.03  ? 387 ASP A OD1 1 
ATOM   2441  O OD2 . ASP A 1 387 ? 104.485 107.663 127.463 1.00 40.49  ? 387 ASP A OD2 1 
ATOM   2442  N N   . ARG A 1 388 ? 104.726 102.897 130.514 1.00 36.49  ? 388 ARG A N   1 
ATOM   2443  C CA  . ARG A 1 388 ? 104.139 101.684 131.111 1.00 35.98  ? 388 ARG A CA  1 
ATOM   2444  C C   . ARG A 1 388 ? 104.859 101.160 132.360 1.00 38.06  ? 388 ARG A C   1 
ATOM   2445  O O   . ARG A 1 388 ? 104.393 100.199 132.963 1.00 49.12  ? 388 ARG A O   1 
ATOM   2446  C CB  . ARG A 1 388 ? 103.907 100.615 130.034 1.00 34.95  ? 388 ARG A CB  1 
ATOM   2447  C CG  . ARG A 1 388 ? 105.183 99.957  129.505 1.00 39.96  ? 388 ARG A CG  1 
ATOM   2448  C CD  . ARG A 1 388 ? 104.916 99.089  128.271 1.00 42.49  ? 388 ARG A CD  1 
ATOM   2449  N NE  . ARG A 1 388 ? 104.494 99.898  127.108 1.00 48.12  ? 388 ARG A NE  1 
ATOM   2450  C CZ  . ARG A 1 388 ? 103.556 99.607  126.227 1.00 52.15  ? 388 ARG A CZ  1 
ATOM   2451  N NH1 . ARG A 1 388 ? 103.253 100.424 125.264 1.00 45.50  ? 388 ARG A NH1 1 
ATOM   2452  N NH2 . ARG A 1 388 ? 102.882 98.497  126.275 1.00 49.05  ? 388 ARG A NH2 1 
ATOM   2453  N N   . LEU A 1 389 ? 105.967 101.780 132.769 1.00 29.75  ? 389 LEU A N   1 
ATOM   2454  C CA  . LEU A 1 389 ? 106.757 101.417 133.954 1.00 22.38  ? 389 LEU A CA  1 
ATOM   2455  C C   . LEU A 1 389 ? 106.857 102.526 135.004 1.00 27.58  ? 389 LEU A C   1 
ATOM   2456  O O   . LEU A 1 389 ? 107.267 102.253 136.125 1.00 35.04  ? 389 LEU A O   1 
ATOM   2457  C CB  . LEU A 1 389 ? 108.162 100.979 133.525 1.00 28.34  ? 389 LEU A CB  1 
ATOM   2458  C CG  . LEU A 1 389 ? 108.212 99.605  132.851 1.00 27.26  ? 389 LEU A CG  1 
ATOM   2459  C CD1 . LEU A 1 389 ? 109.592 99.375  132.255 1.00 27.99  ? 389 LEU A CD1 1 
ATOM   2460  C CD2 . LEU A 1 389 ? 107.932 98.489  133.852 1.00 26.30  ? 389 LEU A CD2 1 
ATOM   2461  N N   . VAL A 1 390 ? 106.460 103.758 134.702 1.00 24.53  ? 390 VAL A N   1 
ATOM   2462  C CA  . VAL A 1 390 ? 106.553 104.897 135.626 1.00 26.50  ? 390 VAL A CA  1 
ATOM   2463  C C   . VAL A 1 390 ? 105.802 104.671 136.942 1.00 28.24  ? 390 VAL A C   1 
ATOM   2464  O O   . VAL A 1 390 ? 106.269 105.072 138.001 1.00 37.10  ? 390 VAL A O   1 
ATOM   2465  C CB  . VAL A 1 390 ? 106.111 106.183 134.909 1.00 28.26  ? 390 VAL A CB  1 
ATOM   2466  C CG1 . VAL A 1 390 ? 104.627 106.213 134.544 1.00 27.47  ? 390 VAL A CG1 1 
ATOM   2467  C CG2 . VAL A 1 390 ? 106.413 107.423 135.745 1.00 30.02  ? 390 VAL A CG2 1 
ATOM   2468  N N   . SER A 1 391 ? 104.682 103.950 136.919 1.00 31.34  ? 391 SER A N   1 
ATOM   2469  C CA  . SER A 1 391 ? 103.941 103.567 138.125 1.00 23.98  ? 391 SER A CA  1 
ATOM   2470  C C   . SER A 1 391 ? 104.725 102.581 139.004 1.00 26.49  ? 391 SER A C   1 
ATOM   2471  O O   . SER A 1 391 ? 104.714 102.713 140.225 1.00 34.89  ? 391 SER A O   1 
ATOM   2472  C CB  . SER A 1 391 ? 102.587 102.982 137.732 1.00 24.82  ? 391 SER A CB  1 
ATOM   2473  O OG  . SER A 1 391 ? 102.745 101.866 136.877 1.00 35.23  ? 391 SER A OG  1 
ATOM   2474  N N   . ARG A 1 392 ? 105.460 101.635 138.406 1.00 28.35  ? 392 ARG A N   1 
ATOM   2475  C CA  . ARG A 1 392 ? 106.382 100.726 139.100 1.00 20.04  ? 392 ARG A CA  1 
ATOM   2476  C C   . ARG A 1 392 ? 107.598 101.457 139.655 1.00 20.35  ? 392 ARG A C   1 
ATOM   2477  O O   . ARG A 1 392 ? 108.001 101.183 140.775 1.00 35.11  ? 392 ARG A O   1 
ATOM   2478  C CB  . ARG A 1 392 ? 106.776 99.582  138.161 1.00 27.91  ? 392 ARG A CB  1 
ATOM   2479  C CG  . ARG A 1 392 ? 107.689 98.556  138.844 1.00 22.94  ? 392 ARG A CG  1 
ATOM   2480  C CD  . ARG A 1 392 ? 107.891 97.304  137.994 1.00 33.01  ? 392 ARG A CD  1 
ATOM   2481  N NE  . ARG A 1 392 ? 106.646 96.510  137.892 1.00 45.97  ? 392 ARG A NE  1 
ATOM   2482  C CZ  . ARG A 1 392 ? 106.464 95.240  138.205 1.00 42.44  ? 392 ARG A CZ  1 
ATOM   2483  N NH1 . ARG A 1 392 ? 105.279 94.716  138.150 1.00 39.39  ? 392 ARG A NH1 1 
ATOM   2484  N NH2 . ARG A 1 392 ? 107.435 94.461  138.572 1.00 37.13  ? 392 ARG A NH2 1 
ATOM   2485  N N   . PHE A 1 393 ? 108.137 102.439 138.943 1.00 24.34  ? 393 PHE A N   1 
ATOM   2486  C CA  . PHE A 1 393 ? 109.221 103.285 139.439 1.00 10.16  ? 393 PHE A CA  1 
ATOM   2487  C C   . PHE A 1 393 ? 108.842 104.019 140.734 1.00 17.33  ? 393 PHE A C   1 
ATOM   2488  O O   . PHE A 1 393 ? 109.569 103.978 141.722 1.00 29.00  ? 393 PHE A O   1 
ATOM   2489  C CB  . PHE A 1 393 ? 109.634 104.283 138.354 1.00 14.00  ? 393 PHE A CB  1 
ATOM   2490  C CG  . PHE A 1 393 ? 110.880 105.064 138.696 1.00 17.89  ? 393 PHE A CG  1 
ATOM   2491  C CD1 . PHE A 1 393 ? 112.145 104.483 138.490 1.00 10.85  ? 393 PHE A CD1 1 
ATOM   2492  C CD2 . PHE A 1 393 ? 110.787 106.344 139.266 1.00 16.94  ? 393 PHE A CD2 1 
ATOM   2493  C CE1 . PHE A 1 393 ? 113.307 105.186 138.835 1.00 9.51   ? 393 PHE A CE1 1 
ATOM   2494  C CE2 . PHE A 1 393 ? 111.953 107.038 139.629 1.00 17.30  ? 393 PHE A CE2 1 
ATOM   2495  C CZ  . PHE A 1 393 ? 113.210 106.461 139.405 1.00 12.15  ? 393 PHE A CZ  1 
ATOM   2496  N N   . PHE A 1 394 ? 107.671 104.652 140.762 1.00 26.46  ? 394 PHE A N   1 
ATOM   2497  C CA  . PHE A 1 394 ? 107.200 105.364 141.944 1.00 15.58  ? 394 PHE A CA  1 
ATOM   2498  C C   . PHE A 1 394 ? 106.635 104.448 143.040 1.00 15.63  ? 394 PHE A C   1 
ATOM   2499  O O   . PHE A 1 394 ? 106.731 104.801 144.209 1.00 24.16  ? 394 PHE A O   1 
ATOM   2500  C CB  . PHE A 1 394 ? 106.274 106.503 141.530 1.00 17.93  ? 394 PHE A CB  1 
ATOM   2501  C CG  . PHE A 1 394 ? 107.033 107.632 140.860 1.00 19.60  ? 394 PHE A CG  1 
ATOM   2502  C CD1 . PHE A 1 394 ? 107.976 108.370 141.598 1.00 23.67  ? 394 PHE A CD1 1 
ATOM   2503  C CD2 . PHE A 1 394 ? 106.826 107.939 139.506 1.00 22.61  ? 394 PHE A CD2 1 
ATOM   2504  C CE1 . PHE A 1 394 ? 108.709 109.400 140.987 1.00 26.07  ? 394 PHE A CE1 1 
ATOM   2505  C CE2 . PHE A 1 394 ? 107.547 108.980 138.898 1.00 18.06  ? 394 PHE A CE2 1 
ATOM   2506  C CZ  . PHE A 1 394 ? 108.485 109.708 139.639 1.00 20.79  ? 394 PHE A CZ  1 
ATOM   2507  N N   . PHE A 1 395 ? 106.186 103.231 142.733 1.00 21.41  ? 395 PHE A N   1 
ATOM   2508  C CA  . PHE A 1 395 ? 105.993 102.187 143.736 1.00 16.85  ? 395 PHE A CA  1 
ATOM   2509  C C   . PHE A 1 395 ? 107.313 101.755 144.397 1.00 21.55  ? 395 PHE A C   1 
ATOM   2510  O O   . PHE A 1 395 ? 107.384 101.646 145.619 1.00 29.03  ? 395 PHE A O   1 
ATOM   2511  C CB  . PHE A 1 395 ? 105.281 100.992 143.103 1.00 19.00  ? 395 PHE A CB  1 
ATOM   2512  C CG  . PHE A 1 395 ? 105.146 99.809  144.033 1.00 25.43  ? 395 PHE A CG  1 
ATOM   2513  C CD1 . PHE A 1 395 ? 104.180 99.829  145.053 1.00 20.72  ? 395 PHE A CD1 1 
ATOM   2514  C CD2 . PHE A 1 395 ? 106.006 98.702  143.909 1.00 23.55  ? 395 PHE A CD2 1 
ATOM   2515  C CE1 . PHE A 1 395 ? 104.073 98.749  145.941 1.00 25.07  ? 395 PHE A CE1 1 
ATOM   2516  C CE2 . PHE A 1 395 ? 105.892 97.621  144.790 1.00 24.62  ? 395 PHE A CE2 1 
ATOM   2517  C CZ  . PHE A 1 395 ? 104.925 97.642  145.809 1.00 26.14  ? 395 PHE A CZ  1 
ATOM   2518  N N   . ASN A 1 396 ? 108.385 101.555 143.630 1.00 30.67  ? 396 ASN A N   1 
ATOM   2519  C CA  . ASN A 1 396 ? 109.711 101.246 144.168 1.00 18.26  ? 396 ASN A CA  1 
ATOM   2520  C C   . ASN A 1 396 ? 110.250 102.384 145.055 1.00 17.73  ? 396 ASN A C   1 
ATOM   2521  O O   . ASN A 1 396 ? 110.770 102.124 146.136 1.00 28.15  ? 396 ASN A O   1 
ATOM   2522  C CB  . ASN A 1 396 ? 110.679 100.956 143.012 1.00 17.22  ? 396 ASN A CB  1 
ATOM   2523  C CG  . ASN A 1 396 ? 110.400 99.680  142.247 1.00 20.73  ? 396 ASN A CG  1 
ATOM   2524  O OD1 . ASN A 1 396 ? 109.648 98.815  142.659 1.00 28.69  ? 396 ASN A OD1 1 
ATOM   2525  N ND2 . ASN A 1 396 ? 111.036 99.504  141.113 1.00 26.65  ? 396 ASN A ND2 1 
ATOM   2526  N N   . PHE A 1 397 ? 110.073 103.641 144.643 1.00 19.54  ? 397 PHE A N   1 
ATOM   2527  C CA  . PHE A 1 397 ? 110.377 104.824 145.447 1.00 8.69   ? 397 PHE A CA  1 
ATOM   2528  C C   . PHE A 1 397 ? 109.573 104.872 146.747 1.00 27.68  ? 397 PHE A C   1 
ATOM   2529  O O   . PHE A 1 397 ? 110.147 105.092 147.808 1.00 36.59  ? 397 PHE A O   1 
ATOM   2530  C CB  . PHE A 1 397 ? 110.092 106.081 144.626 1.00 13.60  ? 397 PHE A CB  1 
ATOM   2531  C CG  . PHE A 1 397 ? 110.152 107.378 145.399 1.00 23.85  ? 397 PHE A CG  1 
ATOM   2532  C CD1 . PHE A 1 397 ? 111.334 107.767 146.051 1.00 23.01  ? 397 PHE A CD1 1 
ATOM   2533  C CD2 . PHE A 1 397 ? 109.015 108.200 145.489 1.00 26.90  ? 397 PHE A CD2 1 
ATOM   2534  C CE1 . PHE A 1 397 ? 111.407 108.997 146.719 1.00 16.03  ? 397 PHE A CE1 1 
ATOM   2535  C CE2 . PHE A 1 397 ? 109.074 109.412 146.195 1.00 28.46  ? 397 PHE A CE2 1 
ATOM   2536  C CZ  . PHE A 1 397 ? 110.275 109.819 146.793 1.00 27.22  ? 397 PHE A CZ  1 
ATOM   2537  N N   . ALA A 1 398 ? 108.258 104.642 146.699 1.00 30.91  ? 398 ALA A N   1 
ATOM   2538  C CA  . ALA A 1 398 ? 107.407 104.621 147.880 1.00 11.33  ? 398 ALA A CA  1 
ATOM   2539  C C   . ALA A 1 398 ? 107.809 103.523 148.875 1.00 19.45  ? 398 ALA A C   1 
ATOM   2540  O O   . ALA A 1 398 ? 107.837 103.766 150.076 1.00 32.40  ? 398 ALA A O   1 
ATOM   2541  C CB  . ALA A 1 398 ? 105.958 104.460 147.423 1.00 23.88  ? 398 ALA A CB  1 
ATOM   2542  N N   . CYS A 1 399 ? 108.191 102.336 148.403 1.00 26.04  ? 399 CYS A N   1 
ATOM   2543  C CA  . CYS A 1 399 ? 108.707 101.272 149.261 1.00 23.70  ? 399 CYS A CA  1 
ATOM   2544  C C   . CYS A 1 399 ? 110.043 101.647 149.909 1.00 22.52  ? 399 CYS A C   1 
ATOM   2545  O O   . CYS A 1 399 ? 110.246 101.358 151.087 1.00 33.30  ? 399 CYS A O   1 
ATOM   2546  C CB  . CYS A 1 399 ? 108.815 99.967  148.466 1.00 27.96  ? 399 CYS A CB  1 
ATOM   2547  S SG  . CYS A 1 399 ? 107.164 99.455  147.949 1.00 38.78  ? 399 CYS A SG  1 
ATOM   2548  N N   . TYR A 1 400 ? 110.936 102.339 149.193 1.00 20.58  ? 400 TYR A N   1 
ATOM   2549  C CA  . TYR A 1 400 ? 112.189 102.819 149.773 1.00 14.04  ? 400 TYR A CA  1 
ATOM   2550  C C   . TYR A 1 400 ? 111.973 103.981 150.752 1.00 21.68  ? 400 TYR A C   1 
ATOM   2551  O O   . TYR A 1 400 ? 112.596 104.012 151.805 1.00 31.27  ? 400 TYR A O   1 
ATOM   2552  C CB  . TYR A 1 400 ? 113.205 103.157 148.677 1.00 11.33  ? 400 TYR A CB  1 
ATOM   2553  C CG  . TYR A 1 400 ? 114.627 103.233 149.204 1.00 20.38  ? 400 TYR A CG  1 
ATOM   2554  C CD1 . TYR A 1 400 ? 115.268 102.054 149.622 1.00 19.76  ? 400 TYR A CD1 1 
ATOM   2555  C CD2 . TYR A 1 400 ? 115.304 104.458 149.313 1.00 5.90   ? 400 TYR A CD2 1 
ATOM   2556  C CE1 . TYR A 1 400 ? 116.555 102.101 150.171 1.00 19.78  ? 400 TYR A CE1 1 
ATOM   2557  C CE2 . TYR A 1 400 ? 116.608 104.508 149.839 1.00 6.35   ? 400 TYR A CE2 1 
ATOM   2558  C CZ  . TYR A 1 400 ? 117.230 103.325 150.275 1.00 22.64  ? 400 TYR A CZ  1 
ATOM   2559  O OH  . TYR A 1 400 ? 118.481 103.330 150.799 1.00 31.03  ? 400 TYR A OH  1 
ATOM   2560  N N   . LEU A 1 401 ? 111.029 104.887 150.482 1.00 15.73  ? 401 LEU A N   1 
ATOM   2561  C CA  . LEU A 1 401 ? 110.595 105.904 151.439 1.00 18.62  ? 401 LEU A CA  1 
ATOM   2562  C C   . LEU A 1 401 ? 110.039 105.287 152.717 1.00 16.93  ? 401 LEU A C   1 
ATOM   2563  O O   . LEU A 1 401 ? 110.417 105.722 153.796 1.00 32.21  ? 401 LEU A O   1 
ATOM   2564  C CB  . LEU A 1 401 ? 109.497 106.801 150.843 1.00 25.57  ? 401 LEU A CB  1 
ATOM   2565  C CG  . LEU A 1 401 ? 109.961 108.079 150.149 1.00 24.97  ? 401 LEU A CG  1 
ATOM   2566  C CD1 . LEU A 1 401 ? 108.706 108.829 149.712 1.00 25.86  ? 401 LEU A CD1 1 
ATOM   2567  C CD2 . LEU A 1 401 ? 110.741 109.014 151.069 1.00 20.32  ? 401 LEU A CD2 1 
ATOM   2568  N N   . VAL A 1 402 ? 109.163 104.287 152.631 1.00 25.55  ? 402 VAL A N   1 
ATOM   2569  C CA  . VAL A 1 402 ? 108.609 103.618 153.814 1.00 22.25  ? 402 VAL A CA  1 
ATOM   2570  C C   . VAL A 1 402 ? 109.707 102.896 154.594 1.00 21.72  ? 402 VAL A C   1 
ATOM   2571  O O   . VAL A 1 402 ? 109.794 103.059 155.806 1.00 35.64  ? 402 VAL A O   1 
ATOM   2572  C CB  . VAL A 1 402 ? 107.451 102.686 153.424 1.00 26.62  ? 402 VAL A CB  1 
ATOM   2573  C CG1 . VAL A 1 402 ? 107.004 101.764 154.560 1.00 25.52  ? 402 VAL A CG1 1 
ATOM   2574  C CG2 . VAL A 1 402 ? 106.237 103.521 153.013 1.00 21.81  ? 402 VAL A CG2 1 
ATOM   2575  N N   . TYR A 1 403 ? 110.604 102.178 153.926 1.00 24.12  ? 403 TYR A N   1 
ATOM   2576  C CA  . TYR A 1 403 ? 111.781 101.596 154.562 1.00 20.00  ? 403 TYR A CA  1 
ATOM   2577  C C   . TYR A 1 403 ? 112.649 102.657 155.257 1.00 22.16  ? 403 TYR A C   1 
ATOM   2578  O O   . TYR A 1 403 ? 112.967 102.488 156.425 1.00 35.89  ? 403 TYR A O   1 
ATOM   2579  C CB  . TYR A 1 403 ? 112.542 100.764 153.524 1.00 20.24  ? 403 TYR A CB  1 
ATOM   2580  C CG  . TYR A 1 403 ? 113.944 100.340 153.905 1.00 26.76  ? 403 TYR A CG  1 
ATOM   2581  C CD1 . TYR A 1 403 ? 114.168 99.262  154.785 1.00 19.73  ? 403 TYR A CD1 1 
ATOM   2582  C CD2 . TYR A 1 403 ? 115.037 101.025 153.342 1.00 29.12  ? 403 TYR A CD2 1 
ATOM   2583  C CE1 . TYR A 1 403 ? 115.487 98.837  155.052 1.00 22.70  ? 403 TYR A CE1 1 
ATOM   2584  C CE2 . TYR A 1 403 ? 116.349 100.609 153.612 1.00 27.04  ? 403 TYR A CE2 1 
ATOM   2585  C CZ  . TYR A 1 403 ? 116.576 99.490  154.438 1.00 27.71  ? 403 TYR A CZ  1 
ATOM   2586  O OH  . TYR A 1 403 ? 117.843 99.022  154.598 1.00 37.47  ? 403 TYR A OH  1 
ATOM   2587  N N   . MET A 1 404 ? 112.974 103.780 154.617 1.00 23.17  ? 404 MET A N   1 
ATOM   2588  C CA  . MET A 1 404 ? 113.787 104.841 155.220 1.00 18.24  ? 404 MET A CA  1 
ATOM   2589  C C   . MET A 1 404 ? 113.079 105.656 156.300 1.00 18.31  ? 404 MET A C   1 
ATOM   2590  O O   . MET A 1 404 ? 113.728 106.109 157.241 1.00 27.92  ? 404 MET A O   1 
ATOM   2591  C CB  . MET A 1 404 ? 114.359 105.774 154.144 1.00 24.33  ? 404 MET A CB  1 
ATOM   2592  C CG  . MET A 1 404 ? 115.494 105.125 153.356 1.00 8.67   ? 404 MET A CG  1 
ATOM   2593  S SD  . MET A 1 404 ? 116.812 104.353 154.335 1.00 25.37  ? 404 MET A SD  1 
ATOM   2594  C CE  . MET A 1 404 ? 117.250 105.687 155.470 1.00 19.69  ? 404 MET A CE  1 
ATOM   2595  N N   . PHE A 1 405 ? 111.761 105.809 156.235 1.00 34.05  ? 405 PHE A N   1 
ATOM   2596  C CA  . PHE A 1 405 ? 110.954 106.345 157.326 1.00 19.76  ? 405 PHE A CA  1 
ATOM   2597  C C   . PHE A 1 405 ? 111.020 105.433 158.558 1.00 24.21  ? 405 PHE A C   1 
ATOM   2598  O O   . PHE A 1 405 ? 111.362 105.905 159.638 1.00 35.22  ? 405 PHE A O   1 
ATOM   2599  C CB  . PHE A 1 405 ? 109.516 106.547 156.844 1.00 22.76  ? 405 PHE A CB  1 
ATOM   2600  C CG  . PHE A 1 405 ? 108.567 106.972 157.939 1.00 37.81  ? 405 PHE A CG  1 
ATOM   2601  C CD1 . PHE A 1 405 ? 108.543 108.306 158.378 1.00 36.47  ? 405 PHE A CD1 1 
ATOM   2602  C CD2 . PHE A 1 405 ? 107.732 106.022 158.558 1.00 37.17  ? 405 PHE A CD2 1 
ATOM   2603  C CE1 . PHE A 1 405 ? 107.699 108.690 159.429 1.00 32.69  ? 405 PHE A CE1 1 
ATOM   2604  C CE2 . PHE A 1 405 ? 106.893 106.406 159.618 1.00 35.47  ? 405 PHE A CE2 1 
ATOM   2605  C CZ  . PHE A 1 405 ? 106.876 107.740 160.052 1.00 35.71  ? 405 PHE A CZ  1 
ATOM   2606  N N   . ILE A 1 406 ? 110.790 104.125 158.407 1.00 26.15  ? 406 ILE A N   1 
ATOM   2607  C CA  . ILE A 1 406 ? 110.927 103.150 159.501 1.00 25.43  ? 406 ILE A CA  1 
ATOM   2608  C C   . ILE A 1 406 ? 112.360 103.143 160.039 1.00 22.60  ? 406 ILE A C   1 
ATOM   2609  O O   . ILE A 1 406 ? 112.552 103.202 161.246 1.00 41.51  ? 406 ILE A O   1 
ATOM   2610  C CB  . ILE A 1 406 ? 110.466 101.744 159.055 1.00 32.73  ? 406 ILE A CB  1 
ATOM   2611  C CG1 . ILE A 1 406 ? 108.944 101.734 158.801 1.00 27.65  ? 406 ILE A CG1 1 
ATOM   2612  C CG2 . ILE A 1 406 ? 110.812 100.655 160.087 1.00 29.96  ? 406 ILE A CG2 1 
ATOM   2613  C CD1 . ILE A 1 406 ? 108.476 100.545 157.960 1.00 29.37  ? 406 ILE A CD1 1 
ATOM   2614  N N   . PHE A 1 407 ? 113.372 103.161 159.171 1.00 24.51  ? 407 PHE A N   1 
ATOM   2615  C CA  . PHE A 1 407 ? 114.779 103.250 159.553 1.00 19.44  ? 407 PHE A CA  1 
ATOM   2616  C C   . PHE A 1 407 ? 115.048 104.466 160.441 1.00 27.59  ? 407 PHE A C   1 
ATOM   2617  O O   . PHE A 1 407 ? 115.687 104.347 161.478 1.00 33.62  ? 407 PHE A O   1 
ATOM   2618  C CB  . PHE A 1 407 ? 115.651 103.285 158.287 1.00 21.91  ? 407 PHE A CB  1 
ATOM   2619  C CG  . PHE A 1 407 ? 117.010 102.631 158.406 1.00 26.88  ? 407 PHE A CG  1 
ATOM   2620  C CD1 . PHE A 1 407 ? 117.934 103.011 159.395 1.00 30.28  ? 407 PHE A CD1 1 
ATOM   2621  C CD2 . PHE A 1 407 ? 117.348 101.612 157.507 1.00 21.37  ? 407 PHE A CD2 1 
ATOM   2622  C CE1 . PHE A 1 407 ? 119.176 102.369 159.488 1.00 22.49  ? 407 PHE A CE1 1 
ATOM   2623  C CE2 . PHE A 1 407 ? 118.587 100.971 157.599 1.00 27.36  ? 407 PHE A CE2 1 
ATOM   2624  C CZ  . PHE A 1 407 ? 119.498 101.340 158.595 1.00 31.92  ? 407 PHE A CZ  1 
ATOM   2625  N N   . THR A 1 408 ? 114.526 105.631 160.068 1.00 29.24  ? 408 THR A N   1 
ATOM   2626  C CA  . THR A 1 408 ? 114.714 106.889 160.796 1.00 20.34  ? 408 THR A CA  1 
ATOM   2627  C C   . THR A 1 408 ? 114.004 106.889 162.138 1.00 25.95  ? 408 THR A C   1 
ATOM   2628  O O   . THR A 1 408 ? 114.613 107.240 163.142 1.00 41.51  ? 408 THR A O   1 
ATOM   2629  C CB  . THR A 1 408 ? 114.237 108.077 159.960 1.00 21.68  ? 408 THR A CB  1 
ATOM   2630  O OG1 . THR A 1 408 ? 114.872 108.036 158.720 1.00 29.67  ? 408 THR A OG1 1 
ATOM   2631  C CG2 . THR A 1 408 ? 114.574 109.424 160.576 1.00 22.10  ? 408 THR A CG2 1 
ATOM   2632  N N   . VAL A 1 409 ? 112.745 106.454 162.184 1.00 29.71  ? 409 VAL A N   1 
ATOM   2633  C CA  . VAL A 1 409 ? 111.984 106.314 163.427 1.00 28.52  ? 409 VAL A CA  1 
ATOM   2634  C C   . VAL A 1 409 ? 112.680 105.348 164.381 1.00 31.65  ? 409 VAL A C   1 
ATOM   2635  O O   . VAL A 1 409 ? 112.814 105.655 165.556 1.00 44.04  ? 409 VAL A O   1 
ATOM   2636  C CB  . VAL A 1 409 ? 110.537 105.879 163.138 1.00 30.59  ? 409 VAL A CB  1 
ATOM   2637  C CG1 . VAL A 1 409 ? 109.770 105.465 164.393 1.00 34.77  ? 409 VAL A CG1 1 
ATOM   2638  C CG2 . VAL A 1 409 ? 109.770 107.030 162.487 1.00 31.85  ? 409 VAL A CG2 1 
ATOM   2639  N N   . VAL A 1 410 ? 113.216 104.228 163.907 1.00 26.27  ? 410 VAL A N   1 
ATOM   2640  C CA  . VAL A 1 410 ? 113.935 103.257 164.742 1.00 32.22  ? 410 VAL A CA  1 
ATOM   2641  C C   . VAL A 1 410 ? 115.301 103.759 165.197 1.00 33.06  ? 410 VAL A C   1 
ATOM   2642  O O   . VAL A 1 410 ? 115.660 103.580 166.357 1.00 43.98  ? 410 VAL A O   1 
ATOM   2643  C CB  . VAL A 1 410 ? 114.070 101.926 163.991 1.00 34.58  ? 410 VAL A CB  1 
ATOM   2644  C CG1 . VAL A 1 410 ? 114.977 100.903 164.679 1.00 35.90  ? 410 VAL A CG1 1 
ATOM   2645  C CG2 . VAL A 1 410 ? 112.698 101.268 163.837 1.00 30.99  ? 410 VAL A CG2 1 
ATOM   2646  N N   . ALA A 1 411 ? 116.083 104.408 164.335 1.00 38.29  ? 411 ALA A N   1 
ATOM   2647  C CA  . ALA A 1 411 ? 117.382 104.959 164.716 1.00 35.52  ? 411 ALA A CA  1 
ATOM   2648  C C   . ALA A 1 411 ? 117.265 106.093 165.749 1.00 39.06  ? 411 ALA A C   1 
ATOM   2649  O O   . ALA A 1 411 ? 118.071 106.179 166.669 1.00 43.69  ? 411 ALA A O   1 
ATOM   2650  C CB  . ALA A 1 411 ? 118.099 105.420 163.449 1.00 35.36  ? 411 ALA A CB  1 
ATOM   2651  N N   . TYR A 1 412 ? 116.221 106.917 165.659 1.00 40.82  ? 412 TYR A N   1 
ATOM   2652  C CA  . TYR A 1 412 ? 115.952 107.991 166.608 1.00 37.29  ? 412 TYR A CA  1 
ATOM   2653  C C   . TYR A 1 412 ? 115.487 107.496 167.996 1.00 43.20  ? 412 TYR A C   1 
ATOM   2654  O O   . TYR A 1 412 ? 115.651 108.216 168.980 1.00 49.97  ? 412 TYR A O   1 
ATOM   2655  C CB  . TYR A 1 412 ? 114.939 108.939 165.965 1.00 38.24  ? 412 TYR A CB  1 
ATOM   2656  C CG  . TYR A 1 412 ? 114.684 110.214 166.743 1.00 45.39  ? 412 TYR A CG  1 
ATOM   2657  C CD1 . TYR A 1 412 ? 115.523 111.327 166.564 1.00 43.62  ? 412 TYR A CD1 1 
ATOM   2658  C CD2 . TYR A 1 412 ? 113.598 110.296 167.629 1.00 47.21  ? 412 TYR A CD2 1 
ATOM   2659  C CE1 . TYR A 1 412 ? 115.253 112.529 167.246 1.00 44.42  ? 412 TYR A CE1 1 
ATOM   2660  C CE2 . TYR A 1 412 ? 113.329 111.489 168.319 1.00 47.45  ? 412 TYR A CE2 1 
ATOM   2661  C CZ  . TYR A 1 412 ? 114.147 112.616 168.118 1.00 49.03  ? 412 TYR A CZ  1 
ATOM   2662  O OH  . TYR A 1 412 ? 113.880 113.763 168.793 1.00 49.61  ? 412 TYR A OH  1 
ATOM   2663  N N   . HIS A 1 413 ? 114.960 106.274 168.114 1.00 43.23  ? 413 HIS A N   1 
ATOM   2664  C CA  . HIS A 1 413 ? 114.438 105.692 169.360 1.00 42.12  ? 413 HIS A CA  1 
ATOM   2665  C C   . HIS A 1 413 ? 115.288 104.543 169.929 1.00 46.09  ? 413 HIS A C   1 
ATOM   2666  O O   . HIS A 1 413 ? 114.791 103.750 170.726 1.00 54.82  ? 413 HIS A O   1 
ATOM   2667  C CB  . HIS A 1 413 ? 112.960 105.306 169.203 1.00 40.56  ? 413 HIS A CB  1 
ATOM   2668  C CG  . HIS A 1 413 ? 112.041 106.465 168.942 1.00 41.51  ? 413 HIS A CG  1 
ATOM   2669  N ND1 . HIS A 1 413 ? 111.665 106.941 167.715 1.00 45.94  ? 413 HIS A ND1 1 
ATOM   2670  C CD2 . HIS A 1 413 ? 111.431 107.253 169.875 1.00 44.67  ? 413 HIS A CD2 1 
ATOM   2671  C CE1 . HIS A 1 413 ? 110.828 107.969 167.891 1.00 47.38  ? 413 HIS A CE1 1 
ATOM   2672  N NE2 . HIS A 1 413 ? 110.664 108.213 169.201 1.00 45.05  ? 413 HIS A NE2 1 
ATOM   2673  N N   . GLN A 1 414 ? 116.575 104.475 169.599 1.00 44.89  ? 414 GLN A N   1 
ATOM   2674  C CA  . GLN A 1 414 ? 117.499 103.533 170.231 1.00 48.82  ? 414 GLN A CA  1 
ATOM   2675  C C   . GLN A 1 414 ? 117.614 103.785 171.749 1.00 53.51  ? 414 GLN A C   1 
ATOM   2676  O O   . GLN A 1 414 ? 117.772 104.940 172.159 1.00 55.14  ? 414 GLN A O   1 
ATOM   2677  C CB  . GLN A 1 414 ? 118.889 103.645 169.589 1.00 49.37  ? 414 GLN A CB  1 
ATOM   2678  C CG  . GLN A 1 414 ? 118.886 103.233 168.114 1.00 48.87  ? 414 GLN A CG  1 
ATOM   2679  C CD  . GLN A 1 414 ? 118.508 101.779 167.915 1.00 52.71  ? 414 GLN A CD  1 
ATOM   2680  O OE1 . GLN A 1 414 ? 119.124 100.879 168.451 1.00 54.97  ? 414 GLN A OE1 1 
ATOM   2681  N NE2 . GLN A 1 414 ? 117.491 101.495 167.148 1.00 50.97  ? 414 GLN A NE2 1 
ATOM   2682  N N   . PRO A 1 415 ? 117.566 102.741 172.597 1.00 61.82  ? 415 PRO A N   1 
ATOM   2683  C CA  . PRO A 1 415 ? 117.758 102.875 174.038 1.00 61.01  ? 415 PRO A CA  1 
ATOM   2684  C C   . PRO A 1 415 ? 119.229 103.138 174.391 1.00 61.39  ? 415 PRO A C   1 
ATOM   2685  O O   . PRO A 1 415 ? 120.129 102.892 173.588 1.00 61.65  ? 415 PRO A O   1 
ATOM   2686  C CB  . PRO A 1 415 ? 117.257 101.551 174.625 1.00 60.53  ? 415 PRO A CB  1 
ATOM   2687  C CG  . PRO A 1 415 ? 117.582 100.543 173.528 1.00 59.50  ? 415 PRO A CG  1 
ATOM   2688  C CD  . PRO A 1 415 ? 117.348 101.343 172.249 1.00 59.05  ? 415 PRO A CD  1 
ATOM   2689  N N   . SER A 1 416 ? 119.484 103.599 175.616 1.00 66.75  ? 416 SER A N   1 
ATOM   2690  C CA  . SER A 1 416 ? 120.840 103.697 176.168 1.00 68.58  ? 416 SER A CA  1 
ATOM   2691  C C   . SER A 1 416 ? 121.504 102.316 176.272 1.00 70.01  ? 416 SER A C   1 
ATOM   2692  O O   . SER A 1 416 ? 120.837 101.318 176.556 1.00 69.71  ? 416 SER A O   1 
ATOM   2693  C CB  . SER A 1 416 ? 120.790 104.375 177.540 1.00 68.79  ? 416 SER A CB  1 
ATOM   2694  O OG  . SER A 1 416 ? 122.094 104.550 178.059 1.00 69.23  ? 416 SER A OG  1 
ATOM   2695  N N   . LEU A 1 417 ? 122.814 102.238 176.027 1.00 70.25  ? 417 LEU A N   1 
ATOM   2696  C CA  . LEU A 1 417 ? 123.557 100.974 175.988 1.00 71.33  ? 417 LEU A CA  1 
ATOM   2697  C C   . LEU A 1 417 ? 123.886 100.437 177.392 1.00 71.83  ? 417 LEU A C   1 
ATOM   2698  O O   . LEU A 1 417 ? 124.443 101.139 178.242 1.00 69.22  ? 417 LEU A O   1 
ATOM   2699  C CB  . LEU A 1 417 ? 124.815 101.101 175.107 1.00 69.38  ? 417 LEU A CB  1 
ATOM   2700  C CG  . LEU A 1 417 ? 124.574 101.655 173.687 1.00 70.14  ? 417 LEU A CG  1 
ATOM   2701  C CD1 . LEU A 1 417 ? 125.822 101.450 172.832 1.00 71.08  ? 417 LEU A CD1 1 
ATOM   2702  C CD2 . LEU A 1 417 ? 123.419 100.963 172.973 1.00 70.39  ? 417 LEU A CD2 1 
ATOM   2703  N N   . PHE A 1 429 ? 104.505 98.653  175.217 1.00 75.29  ? 429 PHE A N   1 
ATOM   2704  C CA  . PHE A 1 429 ? 104.091 98.621  173.817 1.00 76.49  ? 429 PHE A CA  1 
ATOM   2705  C C   . PHE A 1 429 ? 105.178 99.159  172.879 1.00 76.10  ? 429 PHE A C   1 
ATOM   2706  O O   . PHE A 1 429 ? 105.522 98.503  171.891 1.00 76.57  ? 429 PHE A O   1 
ATOM   2707  C CB  . PHE A 1 429 ? 102.792 99.424  173.662 1.00 75.45  ? 429 PHE A CB  1 
ATOM   2708  C CG  . PHE A 1 429 ? 102.372 99.662  172.223 1.00 75.47  ? 429 PHE A CG  1 
ATOM   2709  C CD1 . PHE A 1 429 ? 101.926 98.587  171.435 1.00 74.70  ? 429 PHE A CD1 1 
ATOM   2710  C CD2 . PHE A 1 429 ? 102.418 100.957 171.671 1.00 76.37  ? 429 PHE A CD2 1 
ATOM   2711  C CE1 . PHE A 1 429 ? 101.503 98.809  170.114 1.00 75.62  ? 429 PHE A CE1 1 
ATOM   2712  C CE2 . PHE A 1 429 ? 101.994 101.178 170.354 1.00 75.86  ? 429 PHE A CE2 1 
ATOM   2713  C CZ  . PHE A 1 429 ? 101.525 100.103 169.578 1.00 75.61  ? 429 PHE A CZ  1 
ATOM   2714  N N   . GLY A 1 430 ? 105.770 100.305 173.210 1.00 75.31  ? 430 GLY A N   1 
ATOM   2715  C CA  . GLY A 1 430 ? 106.797 100.966 172.402 1.00 73.39  ? 430 GLY A CA  1 
ATOM   2716  C C   . GLY A 1 430 ? 108.059 100.120 172.215 1.00 73.23  ? 430 GLY A C   1 
ATOM   2717  O O   . GLY A 1 430 ? 108.652 100.133 171.139 1.00 75.17  ? 430 GLY A O   1 
ATOM   2718  N N   . GLU A 1 431 ? 108.426 99.299  173.198 1.00 70.66  ? 431 GLU A N   1 
ATOM   2719  C CA  . GLU A 1 431 ? 109.521 98.334  173.076 1.00 69.47  ? 431 GLU A CA  1 
ATOM   2720  C C   . GLU A 1 431 ? 109.227 97.218  172.064 1.00 70.48  ? 431 GLU A C   1 
ATOM   2721  O O   . GLU A 1 431 ? 110.127 96.787  171.345 1.00 71.10  ? 431 GLU A O   1 
ATOM   2722  C CB  . GLU A 1 431 ? 109.795 97.739  174.455 1.00 68.59  ? 431 GLU A CB  1 
ATOM   2723  N N   . SER A 1 432 ? 107.967 96.782  171.937 1.00 70.20  ? 432 SER A N   1 
ATOM   2724  C CA  . SER A 1 432 ? 107.559 95.800  170.920 1.00 70.70  ? 432 SER A CA  1 
ATOM   2725  C C   . SER A 1 432 ? 107.534 96.402  169.509 1.00 70.93  ? 432 SER A C   1 
ATOM   2726  O O   . SER A 1 432 ? 108.005 95.784  168.561 1.00 70.10  ? 432 SER A O   1 
ATOM   2727  C CB  . SER A 1 432 ? 106.212 95.160  171.287 1.00 71.11  ? 432 SER A CB  1 
ATOM   2728  O OG  . SER A 1 432 ? 105.098 95.979  170.981 1.00 73.10  ? 432 SER A OG  1 
ATOM   2729  N N   . MET A 1 433 ? 107.078 97.652  169.366 1.00 67.85  ? 433 MET A N   1 
ATOM   2730  C CA  . MET A 1 433 ? 107.149 98.383  168.100 1.00 65.56  ? 433 MET A CA  1 
ATOM   2731  C C   . MET A 1 433 ? 108.589 98.682  167.677 1.00 65.22  ? 433 MET A C   1 
ATOM   2732  O O   . MET A 1 433 ? 108.902 98.624  166.491 1.00 68.18  ? 433 MET A O   1 
ATOM   2733  C CB  . MET A 1 433 ? 106.328 99.677  168.189 1.00 65.66  ? 433 MET A CB  1 
ATOM   2734  C CG  . MET A 1 433 ? 104.835 99.398  168.016 1.00 68.60  ? 433 MET A CG  1 
ATOM   2735  S SD  . MET A 1 433 ? 104.421 98.818  166.349 1.00 78.83  ? 433 MET A SD  1 
ATOM   2736  C CE  . MET A 1 433 ? 102.648 98.526  166.534 1.00 67.37  ? 433 MET A CE  1 
ATOM   2737  N N   . LEU A 1 434 ? 109.497 98.926  168.622 1.00 56.02  ? 434 LEU A N   1 
ATOM   2738  C CA  . LEU A 1 434 ? 110.919 99.064  168.329 1.00 56.03  ? 434 LEU A CA  1 
ATOM   2739  C C   . LEU A 1 434 ? 111.545 97.737  167.863 1.00 58.14  ? 434 LEU A C   1 
ATOM   2740  O O   . LEU A 1 434 ? 112.333 97.743  166.923 1.00 60.37  ? 434 LEU A O   1 
ATOM   2741  C CB  . LEU A 1 434 ? 111.632 99.658  169.556 1.00 57.75  ? 434 LEU A CB  1 
ATOM   2742  C CG  . LEU A 1 434 ? 113.093 100.044 169.283 1.00 57.04  ? 434 LEU A CG  1 
ATOM   2743  C CD1 . LEU A 1 434 ? 113.212 101.224 168.316 1.00 56.19  ? 434 LEU A CD1 1 
ATOM   2744  C CD2 . LEU A 1 434 ? 113.788 100.428 170.578 1.00 56.70  ? 434 LEU A CD2 1 
ATOM   2745  N N   . LEU A 1 435 ? 111.178 96.595  168.455 1.00 57.91  ? 435 LEU A N   1 
ATOM   2746  C CA  . LEU A 1 435 ? 111.587 95.267  167.973 1.00 59.40  ? 435 LEU A CA  1 
ATOM   2747  C C   . LEU A 1 435 ? 111.064 94.980  166.555 1.00 58.86  ? 435 LEU A C   1 
ATOM   2748  O O   . LEU A 1 435 ? 111.829 94.541  165.699 1.00 56.11  ? 435 LEU A O   1 
ATOM   2749  C CB  . LEU A 1 435 ? 111.117 94.202  168.977 1.00 61.73  ? 435 LEU A CB  1 
ATOM   2750  C CG  . LEU A 1 435 ? 111.398 92.747  168.563 1.00 60.67  ? 435 LEU A CG  1 
ATOM   2751  C CD1 . LEU A 1 435 ? 112.893 92.445  168.529 1.00 57.75  ? 435 LEU A CD1 1 
ATOM   2752  C CD2 . LEU A 1 435 ? 110.727 91.796  169.546 1.00 60.66  ? 435 LEU A CD2 1 
ATOM   2753  N N   . LEU A 1 436 ? 109.789 95.281  166.285 1.00 52.84  ? 436 LEU A N   1 
ATOM   2754  C CA  . LEU A 1 436 ? 109.206 95.164  164.948 1.00 50.75  ? 436 LEU A CA  1 
ATOM   2755  C C   . LEU A 1 436 ? 109.982 96.020  163.934 1.00 53.43  ? 436 LEU A C   1 
ATOM   2756  O O   . LEU A 1 436 ? 110.359 95.538  162.871 1.00 54.14  ? 436 LEU A O   1 
ATOM   2757  C CB  . LEU A 1 436 ? 107.714 95.544  164.997 1.00 50.72  ? 436 LEU A CB  1 
ATOM   2758  C CG  . LEU A 1 436 ? 107.020 95.511  163.623 1.00 51.81  ? 436 LEU A CG  1 
ATOM   2759  C CD1 . LEU A 1 436 ? 107.005 94.106  163.022 1.00 53.49  ? 436 LEU A CD1 1 
ATOM   2760  C CD2 . LEU A 1 436 ? 105.579 95.992  163.748 1.00 49.99  ? 436 LEU A CD2 1 
ATOM   2761  N N   . GLY A 1 437 ? 110.295 97.265  164.286 1.00 46.77  ? 437 GLY A N   1 
ATOM   2762  C CA  . GLY A 1 437 ? 111.115 98.145  163.465 1.00 41.77  ? 437 GLY A CA  1 
ATOM   2763  C C   . GLY A 1 437 ? 112.507 97.590  163.157 1.00 42.20  ? 437 GLY A C   1 
ATOM   2764  O O   . GLY A 1 437 ? 112.956 97.683  162.020 1.00 49.59  ? 437 GLY A O   1 
ATOM   2765  N N   . HIS A 1 438 ? 113.185 96.950  164.110 1.00 40.39  ? 438 HIS A N   1 
ATOM   2766  C CA  . HIS A 1 438 ? 114.478 96.308  163.844 1.00 43.77  ? 438 HIS A CA  1 
ATOM   2767  C C   . HIS A 1 438 ? 114.384 95.119  162.884 1.00 47.43  ? 438 HIS A C   1 
ATOM   2768  O O   . HIS A 1 438 ? 115.227 94.997  161.999 1.00 49.93  ? 438 HIS A O   1 
ATOM   2769  C CB  . HIS A 1 438 ? 115.159 95.868  165.142 1.00 48.39  ? 438 HIS A CB  1 
ATOM   2770  C CG  . HIS A 1 438 ? 115.739 97.005  165.932 1.00 48.02  ? 438 HIS A CG  1 
ATOM   2771  N ND1 . HIS A 1 438 ? 115.112 97.717  166.917 1.00 49.15  ? 438 HIS A ND1 1 
ATOM   2772  C CD2 . HIS A 1 438 ? 116.970 97.567  165.757 1.00 46.70  ? 438 HIS A CD2 1 
ATOM   2773  C CE1 . HIS A 1 438 ? 115.948 98.666  167.352 1.00 49.90  ? 438 HIS A CE1 1 
ATOM   2774  N NE2 . HIS A 1 438 ? 117.099 98.616  166.667 1.00 50.94  ? 438 HIS A NE2 1 
ATOM   2775  N N   . ILE A 1 439 ? 113.373 94.255  162.998 1.00 47.25  ? 439 ILE A N   1 
ATOM   2776  C CA  . ILE A 1 439 ? 113.230 93.135  162.057 1.00 45.54  ? 439 ILE A CA  1 
ATOM   2777  C C   . ILE A 1 439 ? 112.740 93.600  160.678 1.00 44.21  ? 439 ILE A C   1 
ATOM   2778  O O   . ILE A 1 439 ? 113.192 93.052  159.680 1.00 44.65  ? 439 ILE A O   1 
ATOM   2779  C CB  . ILE A 1 439 ? 112.421 91.956  162.634 1.00 49.87  ? 439 ILE A CB  1 
ATOM   2780  C CG1 . ILE A 1 439 ? 110.951 92.304  162.908 1.00 49.05  ? 439 ILE A CG1 1 
ATOM   2781  C CG2 . ILE A 1 439 ? 113.132 91.417  163.884 1.00 46.25  ? 439 ILE A CG2 1 
ATOM   2782  C CD1 . ILE A 1 439 ? 110.116 91.150  163.452 1.00 49.34  ? 439 ILE A CD1 1 
ATOM   2783  N N   . LEU A 1 440 ? 111.922 94.654  160.570 1.00 38.85  ? 440 LEU A N   1 
ATOM   2784  C CA  . LEU A 1 440 ? 111.619 95.286  159.281 1.00 37.92  ? 440 LEU A CA  1 
ATOM   2785  C C   . LEU A 1 440 ? 112.868 95.893  158.624 1.00 34.57  ? 440 LEU A C   1 
ATOM   2786  O O   . LEU A 1 440 ? 113.048 95.748  157.421 1.00 45.17  ? 440 LEU A O   1 
ATOM   2787  C CB  . LEU A 1 440 ? 110.508 96.338  159.449 1.00 41.19  ? 440 LEU A CB  1 
ATOM   2788  C CG  . LEU A 1 440 ? 109.124 95.762  159.803 1.00 40.88  ? 440 LEU A CG  1 
ATOM   2789  C CD1 . LEU A 1 440 ? 108.149 96.903  160.052 1.00 36.05  ? 440 LEU A CD1 1 
ATOM   2790  C CD2 . LEU A 1 440 ? 108.540 94.890  158.701 1.00 41.82  ? 440 LEU A CD2 1 
ATOM   2791  N N   . ILE A 1 441 ? 113.768 96.516  159.388 1.00 33.24  ? 441 ILE A N   1 
ATOM   2792  C CA  . ILE A 1 441 ? 115.063 97.011  158.888 1.00 35.26  ? 441 ILE A CA  1 
ATOM   2793  C C   . ILE A 1 441 ? 115.985 95.863  158.475 1.00 35.49  ? 441 ILE A C   1 
ATOM   2794  O O   . ILE A 1 441 ? 116.618 95.944  157.429 1.00 42.52  ? 441 ILE A O   1 
ATOM   2795  C CB  . ILE A 1 441 ? 115.724 97.919  159.946 1.00 40.87  ? 441 ILE A CB  1 
ATOM   2796  C CG1 . ILE A 1 441 ? 114.981 99.260  159.953 1.00 33.92  ? 441 ILE A CG1 1 
ATOM   2797  C CG2 . ILE A 1 441 ? 117.222 98.173  159.722 1.00 39.97  ? 441 ILE A CG2 1 
ATOM   2798  C CD1 . ILE A 1 441 ? 115.250 100.034 161.231 1.00 41.73  ? 441 ILE A CD1 1 
ATOM   2799  N N   . LEU A 1 442 ? 116.037 94.774  159.242 1.00 33.96  ? 442 LEU A N   1 
ATOM   2800  C CA  . LEU A 1 442 ? 116.782 93.571  158.870 1.00 34.35  ? 442 LEU A CA  1 
ATOM   2801  C C   . LEU A 1 442 ? 116.267 92.960  157.558 1.00 36.95  ? 442 LEU A C   1 
ATOM   2802  O O   . LEU A 1 442 ? 117.050 92.715  156.649 1.00 41.91  ? 442 LEU A O   1 
ATOM   2803  C CB  . LEU A 1 442 ? 116.724 92.562  160.027 1.00 36.29  ? 442 LEU A CB  1 
ATOM   2804  C CG  . LEU A 1 442 ? 117.444 91.234  159.755 1.00 36.85  ? 442 LEU A CG  1 
ATOM   2805  C CD1 . LEU A 1 442 ? 118.920 91.414  159.425 1.00 35.73  ? 442 LEU A CD1 1 
ATOM   2806  C CD2 . LEU A 1 442 ? 117.340 90.351  160.988 1.00 36.20  ? 442 LEU A CD2 1 
ATOM   2807  N N   . LEU A 1 443 ? 114.958 92.751  157.428 1.00 38.27  ? 443 LEU A N   1 
ATOM   2808  C CA  . LEU A 1 443 ? 114.340 92.177  156.232 1.00 36.53  ? 443 LEU A CA  1 
ATOM   2809  C C   . LEU A 1 443 ? 114.473 93.090  155.013 1.00 33.14  ? 443 LEU A C   1 
ATOM   2810  O O   . LEU A 1 443 ? 114.833 92.608  153.944 1.00 42.78  ? 443 LEU A O   1 
ATOM   2811  C CB  . LEU A 1 443 ? 112.862 91.862  156.508 1.00 38.93  ? 443 LEU A CB  1 
ATOM   2812  C CG  . LEU A 1 443 ? 112.638 90.704  157.492 1.00 39.46  ? 443 LEU A CG  1 
ATOM   2813  C CD1 . LEU A 1 443 ? 111.159 90.646  157.853 1.00 37.38  ? 443 LEU A CD1 1 
ATOM   2814  C CD2 . LEU A 1 443 ? 113.043 89.354  156.903 1.00 37.28  ? 443 LEU A CD2 1 
ATOM   2815  N N   . GLY A 1 444 ? 114.262 94.400  155.161 1.00 27.99  ? 444 GLY A N   1 
ATOM   2816  C CA  . GLY A 1 444 ? 114.518 95.376  154.104 1.00 21.98  ? 444 GLY A CA  1 
ATOM   2817  C C   . GLY A 1 444 ? 115.986 95.432  153.690 1.00 23.34  ? 444 GLY A C   1 
ATOM   2818  O O   . GLY A 1 444 ? 116.286 95.473  152.504 1.00 36.02  ? 444 GLY A O   1 
ATOM   2819  N N   . GLY A 1 445 ? 116.910 95.328  154.641 1.00 29.28  ? 445 GLY A N   1 
ATOM   2820  C CA  . GLY A 1 445 ? 118.338 95.209  154.376 1.00 29.43  ? 445 GLY A CA  1 
ATOM   2821  C C   . GLY A 1 445 ? 118.707 93.933  153.627 1.00 28.20  ? 445 GLY A C   1 
ATOM   2822  O O   . GLY A 1 445 ? 119.439 94.006  152.650 1.00 36.99  ? 445 GLY A O   1 
ATOM   2823  N N   . ILE A 1 446 ? 118.172 92.774  154.016 1.00 33.74  ? 446 ILE A N   1 
ATOM   2824  C CA  . ILE A 1 446 ? 118.369 91.506  153.298 1.00 33.25  ? 446 ILE A CA  1 
ATOM   2825  C C   . ILE A 1 446 ? 117.771 91.582  151.890 1.00 33.32  ? 446 ILE A C   1 
ATOM   2826  O O   . ILE A 1 446 ? 118.437 91.224  150.927 1.00 35.91  ? 446 ILE A O   1 
ATOM   2827  C CB  . ILE A 1 446 ? 117.791 90.318  154.103 1.00 34.57  ? 446 ILE A CB  1 
ATOM   2828  C CG1 . ILE A 1 446 ? 118.635 90.064  155.368 1.00 30.51  ? 446 ILE A CG1 1 
ATOM   2829  C CG2 . ILE A 1 446 ? 117.737 89.030  153.262 1.00 30.88  ? 446 ILE A CG2 1 
ATOM   2830  C CD1 . ILE A 1 446 ? 117.906 89.217  156.416 1.00 31.51  ? 446 ILE A CD1 1 
ATOM   2831  N N   . TYR A 1 447 ? 116.551 92.089  151.738 1.00 26.21  ? 447 TYR A N   1 
ATOM   2832  C CA  . TYR A 1 447 ? 115.898 92.238  150.444 1.00 23.97  ? 447 TYR A CA  1 
ATOM   2833  C C   . TYR A 1 447 ? 116.694 93.122  149.479 1.00 32.00  ? 447 TYR A C   1 
ATOM   2834  O O   . TYR A 1 447 ? 116.933 92.733  148.338 1.00 47.99  ? 447 TYR A O   1 
ATOM   2835  C CB  . TYR A 1 447 ? 114.505 92.820  150.665 1.00 27.58  ? 447 TYR A CB  1 
ATOM   2836  C CG  . TYR A 1 447 ? 113.727 93.010  149.385 1.00 39.32  ? 447 TYR A CG  1 
ATOM   2837  C CD1 . TYR A 1 447 ? 112.938 91.956  148.905 1.00 32.78  ? 447 TYR A CD1 1 
ATOM   2838  C CD2 . TYR A 1 447 ? 113.816 94.213  148.655 1.00 35.10  ? 447 TYR A CD2 1 
ATOM   2839  C CE1 . TYR A 1 447 ? 112.223 92.103  147.713 1.00 34.84  ? 447 TYR A CE1 1 
ATOM   2840  C CE2 . TYR A 1 447 ? 113.107 94.359  147.449 1.00 34.28  ? 447 TYR A CE2 1 
ATOM   2841  C CZ  . TYR A 1 447 ? 112.310 93.300  146.978 1.00 38.42  ? 447 TYR A CZ  1 
ATOM   2842  O OH  . TYR A 1 447 ? 111.642 93.411  145.807 1.00 40.61  ? 447 TYR A OH  1 
ATOM   2843  N N   . LEU A 1 448 ? 117.142 94.291  149.932 1.00 18.73  ? 448 LEU A N   1 
ATOM   2844  C CA  . LEU A 1 448 ? 117.973 95.185  149.135 1.00 19.00  ? 448 LEU A CA  1 
ATOM   2845  C C   . LEU A 1 448 ? 119.333 94.562  148.824 1.00 24.44  ? 448 LEU A C   1 
ATOM   2846  O O   . LEU A 1 448 ? 119.807 94.680  147.699 1.00 31.24  ? 448 LEU A O   1 
ATOM   2847  C CB  . LEU A 1 448 ? 118.130 96.522  149.867 1.00 23.73  ? 448 LEU A CB  1 
ATOM   2848  C CG  . LEU A 1 448 ? 116.839 97.349  149.914 1.00 30.49  ? 448 LEU A CG  1 
ATOM   2849  C CD1 . LEU A 1 448 ? 116.979 98.432  150.971 1.00 27.41  ? 448 LEU A CD1 1 
ATOM   2850  C CD2 . LEU A 1 448 ? 116.531 98.015  148.577 1.00 31.78  ? 448 LEU A CD2 1 
ATOM   2851  N N   . LEU A 1 449 ? 119.942 93.850  149.771 1.00 28.61  ? 449 LEU A N   1 
ATOM   2852  C CA  . LEU A 1 449 ? 121.202 93.141  149.581 1.00 29.67  ? 449 LEU A CA  1 
ATOM   2853  C C   . LEU A 1 449 ? 121.069 92.060  148.501 1.00 27.67  ? 449 LEU A C   1 
ATOM   2854  O O   . LEU A 1 449 ? 121.852 92.051  147.562 1.00 33.28  ? 449 LEU A O   1 
ATOM   2855  C CB  . LEU A 1 449 ? 121.665 92.575  150.936 1.00 33.70  ? 449 LEU A CB  1 
ATOM   2856  C CG  . LEU A 1 449 ? 122.972 91.783  150.918 1.00 31.24  ? 449 LEU A CG  1 
ATOM   2857  C CD1 . LEU A 1 449 ? 124.125 92.633  150.412 1.00 28.21  ? 449 LEU A CD1 1 
ATOM   2858  C CD2 . LEU A 1 449 ? 123.295 91.317  152.331 1.00 29.05  ? 449 LEU A CD2 1 
ATOM   2859  N N   . LEU A 1 450 ? 120.047 91.205  148.570 1.00 32.41  ? 450 LEU A N   1 
ATOM   2860  C CA  . LEU A 1 450 ? 119.782 90.178  147.559 1.00 30.01  ? 450 LEU A CA  1 
ATOM   2861  C C   . LEU A 1 450 ? 119.499 90.789  146.188 1.00 28.05  ? 450 LEU A C   1 
ATOM   2862  O O   . LEU A 1 450 ? 120.078 90.350  145.199 1.00 41.04  ? 450 LEU A O   1 
ATOM   2863  C CB  . LEU A 1 450 ? 118.612 89.288  148.004 1.00 29.88  ? 450 LEU A CB  1 
ATOM   2864  C CG  . LEU A 1 450 ? 118.929 88.396  149.213 1.00 31.33  ? 450 LEU A CG  1 
ATOM   2865  C CD1 . LEU A 1 450 ? 117.653 87.714  149.686 1.00 30.20  ? 450 LEU A CD1 1 
ATOM   2866  C CD2 . LEU A 1 450 ? 119.952 87.316  148.886 1.00 29.99  ? 450 LEU A CD2 1 
ATOM   2867  N N   . GLY A 1 451 ? 118.680 91.837  146.119 1.00 26.14  ? 451 GLY A N   1 
ATOM   2868  C CA  . GLY A 1 451 ? 118.397 92.532  144.869 1.00 19.13  ? 451 GLY A CA  1 
ATOM   2869  C C   . GLY A 1 451 ? 119.631 93.157  144.220 1.00 23.95  ? 451 GLY A C   1 
ATOM   2870  O O   . GLY A 1 451 ? 119.762 93.143  143.000 1.00 37.48  ? 451 GLY A O   1 
ATOM   2871  N N   . GLN A 1 452 ? 120.560 93.637  145.050 1.00 27.07  ? 452 GLN A N   1 
ATOM   2872  C CA  . GLN A 1 452 ? 121.783 94.303  144.519 1.00 25.63  ? 452 GLN A CA  1 
ATOM   2873  C C   . GLN A 1 452 ? 122.815 93.232  144.130 1.00 27.30  ? 452 GLN A C   1 
ATOM   2874  O O   . GLN A 1 452 ? 123.400 93.369  143.037 1.00 39.57  ? 452 GLN A O   1 
ATOM   2875  C CB  . GLN A 1 452 ? 122.226 95.376  145.521 1.00 30.95  ? 452 GLN A CB  1 
ATOM   2876  C CG  . GLN A 1 452 ? 121.240 96.553  145.546 1.00 27.79  ? 452 GLN A CG  1 
ATOM   2877  C CD  . GLN A 1 452 ? 121.398 97.452  144.344 1.00 28.95  ? 452 GLN A CD  1 
ATOM   2878  O OE1 . GLN A 1 452 ? 122.354 97.337  143.579 1.00 36.07  ? 452 GLN A OE1 1 
ATOM   2879  N NE2 . GLN A 1 452 ? 120.458 98.366  144.173 1.00 39.24  ? 452 GLN A NE2 1 
ATOM   2880  N N   . LEU A 1 453 ? 123.031 92.209  144.965 1.00 32.99  ? 453 LEU A N   1 
ATOM   2881  C CA  . LEU A 1 453 ? 123.905 91.099  144.581 1.00 31.52  ? 453 LEU A CA  1 
ATOM   2882  C C   . LEU A 1 453 ? 123.435 90.459  143.271 1.00 29.21  ? 453 LEU A C   1 
ATOM   2883  O O   . LEU A 1 453 ? 124.251 90.138  142.415 1.00 37.05  ? 453 LEU A O   1 
ATOM   2884  C CB  . LEU A 1 453 ? 123.966 90.056  145.710 1.00 32.78  ? 453 LEU A CB  1 
ATOM   2885  C CG  . LEU A 1 453 ? 124.675 90.532  146.984 1.00 32.27  ? 453 LEU A CG  1 
ATOM   2886  C CD1 . LEU A 1 453 ? 124.500 89.482  148.074 1.00 32.35  ? 453 LEU A CD1 1 
ATOM   2887  C CD2 . LEU A 1 453 ? 126.167 90.763  146.769 1.00 29.54  ? 453 LEU A CD2 1 
ATOM   2888  N N   . TRP A 1 454 ? 122.121 90.334  143.074 1.00 30.12  ? 454 TRP A N   1 
ATOM   2889  C CA  . TRP A 1 454 ? 121.531 89.881  141.819 1.00 29.15  ? 454 TRP A CA  1 
ATOM   2890  C C   . TRP A 1 454 ? 121.793 90.838  140.648 1.00 29.78  ? 454 TRP A C   1 
ATOM   2891  O O   . TRP A 1 454 ? 122.128 90.374  139.563 1.00 41.71  ? 454 TRP A O   1 
ATOM   2892  C CB  . TRP A 1 454 ? 120.037 89.636  142.030 1.00 29.99  ? 454 TRP A CB  1 
ATOM   2893  C CG  . TRP A 1 454 ? 119.283 89.142  140.837 1.00 39.68  ? 454 TRP A CG  1 
ATOM   2894  C CD1 . TRP A 1 454 ? 119.496 87.961  140.213 1.00 38.20  ? 454 TRP A CD1 1 
ATOM   2895  C CD2 . TRP A 1 454 ? 118.192 89.780  140.109 1.00 38.97  ? 454 TRP A CD2 1 
ATOM   2896  N NE1 . TRP A 1 454 ? 118.601 87.818  139.174 1.00 33.21  ? 454 TRP A NE1 1 
ATOM   2897  C CE2 . TRP A 1 454 ? 117.755 88.896  139.084 1.00 37.17  ? 454 TRP A CE2 1 
ATOM   2898  C CE3 . TRP A 1 454 ? 117.523 91.020  140.215 1.00 34.63  ? 454 TRP A CE3 1 
ATOM   2899  C CZ2 . TRP A 1 454 ? 116.701 89.214  138.218 1.00 40.94  ? 454 TRP A CZ2 1 
ATOM   2900  C CZ3 . TRP A 1 454 ? 116.450 91.339  139.363 1.00 41.27  ? 454 TRP A CZ3 1 
ATOM   2901  C CH2 . TRP A 1 454 ? 116.033 90.439  138.368 1.00 38.92  ? 454 TRP A CH2 1 
ATOM   2902  N N   . TYR A 1 455 ? 121.744 92.157  140.851 1.00 35.86  ? 455 TYR A N   1 
ATOM   2903  C CA  . TYR A 1 455 ? 122.162 93.131  139.840 1.00 32.60  ? 455 TYR A CA  1 
ATOM   2904  C C   . TYR A 1 455 ? 123.612 92.904  139.405 1.00 32.49  ? 455 TYR A C   1 
ATOM   2905  O O   . TYR A 1 455 ? 123.881 92.713  138.221 1.00 40.82  ? 455 TYR A O   1 
ATOM   2906  C CB  . TYR A 1 455 ? 121.970 94.569  140.344 1.00 34.39  ? 455 TYR A CB  1 
ATOM   2907  C CG  . TYR A 1 455 ? 122.474 95.624  139.376 1.00 36.31  ? 455 TYR A CG  1 
ATOM   2908  C CD1 . TYR A 1 455 ? 121.638 96.084  138.344 1.00 33.92  ? 455 TYR A CD1 1 
ATOM   2909  C CD2 . TYR A 1 455 ? 123.792 96.112  139.469 1.00 33.24  ? 455 TYR A CD2 1 
ATOM   2910  C CE1 . TYR A 1 455 ? 122.109 97.022  137.412 1.00 33.68  ? 455 TYR A CE1 1 
ATOM   2911  C CE2 . TYR A 1 455 ? 124.278 97.035  138.527 1.00 37.03  ? 455 TYR A CE2 1 
ATOM   2912  C CZ  . TYR A 1 455 ? 123.429 97.504  137.501 1.00 40.58  ? 455 TYR A CZ  1 
ATOM   2913  O OH  . TYR A 1 455 ? 123.865 98.430  136.607 1.00 41.54  ? 455 TYR A OH  1 
ATOM   2914  N N   . PHE A 1 456 ? 124.555 92.862  140.346 1.00 33.35  ? 456 PHE A N   1 
ATOM   2915  C CA  . PHE A 1 456 ? 125.961 92.658  140.009 1.00 31.80  ? 456 PHE A CA  1 
ATOM   2916  C C   . PHE A 1 456 ? 126.260 91.269  139.445 1.00 37.82  ? 456 PHE A C   1 
ATOM   2917  O O   . PHE A 1 456 ? 127.152 91.152  138.613 1.00 44.84  ? 456 PHE A O   1 
ATOM   2918  C CB  . PHE A 1 456 ? 126.848 93.001  141.204 1.00 33.13  ? 456 PHE A CB  1 
ATOM   2919  C CG  . PHE A 1 456 ? 126.926 94.490  141.460 1.00 37.52  ? 456 PHE A CG  1 
ATOM   2920  C CD1 . PHE A 1 456 ? 127.450 95.338  140.468 1.00 39.77  ? 456 PHE A CD1 1 
ATOM   2921  C CD2 . PHE A 1 456 ? 126.453 95.035  142.664 1.00 34.64  ? 456 PHE A CD2 1 
ATOM   2922  C CE1 . PHE A 1 456 ? 127.497 96.724  140.674 1.00 38.82  ? 456 PHE A CE1 1 
ATOM   2923  C CE2 . PHE A 1 456 ? 126.504 96.422  142.872 1.00 32.52  ? 456 PHE A CE2 1 
ATOM   2924  C CZ  . PHE A 1 456 ? 127.027 97.264  141.879 1.00 36.83  ? 456 PHE A CZ  1 
ATOM   2925  N N   . TRP A 1 457 ? 125.498 90.233  139.797 1.00 39.02  ? 457 TRP A N   1 
ATOM   2926  C CA  . TRP A 1 457 ? 125.575 88.937  139.127 1.00 38.16  ? 457 TRP A CA  1 
ATOM   2927  C C   . TRP A 1 457 ? 125.117 89.005  137.667 1.00 43.87  ? 457 TRP A C   1 
ATOM   2928  O O   . TRP A 1 457 ? 125.838 88.574  136.768 1.00 48.05  ? 457 TRP A O   1 
ATOM   2929  C CB  . TRP A 1 457 ? 124.774 87.889  139.895 1.00 44.26  ? 457 TRP A CB  1 
ATOM   2930  C CG  . TRP A 1 457 ? 124.888 86.523  139.300 1.00 48.56  ? 457 TRP A CG  1 
ATOM   2931  C CD1 . TRP A 1 457 ? 123.901 85.843  138.678 1.00 47.80  ? 457 TRP A CD1 1 
ATOM   2932  C CD2 . TRP A 1 457 ? 126.068 85.667  139.244 1.00 45.67  ? 457 TRP A CD2 1 
ATOM   2933  N NE1 . TRP A 1 457 ? 124.388 84.629  138.243 1.00 48.59  ? 457 TRP A NE1 1 
ATOM   2934  C CE2 . TRP A 1 457 ? 125.721 84.467  138.558 1.00 46.65  ? 457 TRP A CE2 1 
ATOM   2935  C CE3 . TRP A 1 457 ? 127.398 85.787  139.698 1.00 45.69  ? 457 TRP A CE3 1 
ATOM   2936  C CZ2 . TRP A 1 457 ? 126.644 83.441  138.338 1.00 46.50  ? 457 TRP A CZ2 1 
ATOM   2937  C CZ3 . TRP A 1 457 ? 128.337 84.762  139.474 1.00 46.27  ? 457 TRP A CZ3 1 
ATOM   2938  C CH2 . TRP A 1 457 ? 127.961 83.593  138.795 1.00 46.80  ? 457 TRP A CH2 1 
ATOM   2939  N N   . ARG A 1 458 ? 123.959 89.618  137.403 1.00 38.90  ? 458 ARG A N   1 
ATOM   2940  C CA  . ARG A 1 458 ? 123.467 89.756  136.000 1.00 37.22  ? 458 ARG A CA  1 
ATOM   2941  C C   . ARG A 1 458 ? 124.447 90.586  135.165 1.00 40.39  ? 458 ARG A C   1 
ATOM   2942  O O   . ARG A 1 458 ? 124.654 90.235  133.987 1.00 48.20  ? 458 ARG A O   1 
ATOM   2943  C CB  . ARG A 1 458 ? 122.066 90.364  135.997 1.00 37.89  ? 458 ARG A CB  1 
ATOM   2944  C CG  . ARG A 1 458 ? 121.007 89.335  136.389 1.00 33.03  ? 458 ARG A CG  1 
ATOM   2945  C CD  . ARG A 1 458 ? 119.607 89.902  136.147 1.00 35.18  ? 458 ARG A CD  1 
ATOM   2946  N NE  . ARG A 1 458 ? 119.278 90.926  137.129 1.00 36.16  ? 458 ARG A NE  1 
ATOM   2947  C CZ  . ARG A 1 458 ? 119.595 92.211  137.018 1.00 40.16  ? 458 ARG A CZ  1 
ATOM   2948  N NH1 . ARG A 1 458 ? 119.250 93.062  137.968 1.00 40.88  ? 458 ARG A NH1 1 
ATOM   2949  N NH2 . ARG A 1 458 ? 120.260 92.641  135.960 1.00 40.85  ? 458 ARG A NH2 1 
ATOM   2950  N N   . ARG A 1 459 ? 125.044 91.614  135.788 1.00 39.12  ? 459 ARG A N   1 
ATOM   2951  C CA  . ARG A 1 459 ? 125.971 92.542  135.086 1.00 40.05  ? 459 ARG A CA  1 
ATOM   2952  C C   . ARG A 1 459 ? 127.442 92.180  135.381 1.00 46.58  ? 459 ARG A C   1 
ATOM   2953  O O   . ARG A 1 459 ? 128.275 93.107  135.344 1.00 50.00  ? 459 ARG A O   1 
ATOM   2954  C CB  . ARG A 1 459 ? 125.698 93.988  135.554 1.00 35.85  ? 459 ARG A CB  1 
ATOM   2955  C CG  . ARG A 1 459 ? 124.244 94.471  135.354 1.00 36.77  ? 459 ARG A CG  1 
ATOM   2956  C CD  . ARG A 1 459 ? 123.790 94.442  133.892 1.00 38.05  ? 459 ARG A CD  1 
ATOM   2957  N NE  . ARG A 1 459 ? 122.354 94.648  133.764 1.00 37.44  ? 459 ARG A NE  1 
ATOM   2958  C CZ  . ARG A 1 459 ? 121.666 94.477  132.641 1.00 43.68  ? 459 ARG A CZ  1 
ATOM   2959  N NH1 . ARG A 1 459 ? 120.361 94.688  132.626 1.00 43.29  ? 459 ARG A NH1 1 
ATOM   2960  N NH2 . ARG A 1 459 ? 122.283 94.089  131.541 1.00 41.17  ? 459 ARG A NH2 1 
ATOM   2961  N N   . ARG A 1 460 ? 127.761 90.888  135.590 1.00 52.55  ? 460 ARG A N   1 
ATOM   2962  C CA  . ARG A 1 460 ? 129.145 90.456  135.986 1.00 50.21  ? 460 ARG A CA  1 
ATOM   2963  C C   . ARG A 1 460 ? 130.132 90.536  134.812 1.00 53.20  ? 460 ARG A C   1 
ATOM   2964  O O   . ARG A 1 460 ? 131.301 90.886  135.061 1.00 53.61  ? 460 ARG A O   1 
ATOM   2965  C CB  . ARG A 1 460 ? 129.131 89.068  136.650 1.00 49.37  ? 460 ARG A CB  1 
ATOM   2966  C CG  . ARG A 1 460 ? 128.774 87.920  135.698 1.00 47.51  ? 460 ARG A CG  1 
ATOM   2967  C CD  . ARG A 1 460 ? 128.480 86.642  136.479 1.00 49.21  ? 460 ARG A CD  1 
ATOM   2968  N NE  . ARG A 1 460 ? 127.967 85.565  135.646 1.00 52.75  ? 460 ARG A NE  1 
ATOM   2969  C CZ  . ARG A 1 460 ? 126.679 85.346  135.406 1.00 54.17  ? 460 ARG A CZ  1 
ATOM   2970  N NH1 . ARG A 1 460 ? 126.311 84.337  134.635 1.00 51.21  ? 460 ARG A NH1 1 
ATOM   2971  N NH2 . ARG A 1 460 ? 125.763 86.136  135.938 1.00 54.53  ? 460 ARG A NH2 1 
ATOM   2972  N N   . LEU A 1 461 ? 129.686 90.236  133.595 1.00 52.83  ? 461 LEU A N   1 
ATOM   2973  C CA  . LEU A 1 461 ? 130.534 90.237  132.391 1.00 52.06  ? 461 LEU A CA  1 
ATOM   2974  C C   . LEU A 1 461 ? 131.046 91.639  132.013 1.00 52.62  ? 461 LEU A C   1 
ATOM   2975  O O   . LEU A 1 461 ? 132.052 91.767  131.320 1.00 54.38  ? 461 LEU A O   1 
ATOM   2976  C CB  . LEU A 1 461 ? 129.765 89.611  131.212 1.00 55.68  ? 461 LEU A CB  1 
ATOM   2977  C CG  . LEU A 1 461 ? 129.280 88.163  131.420 1.00 56.25  ? 461 LEU A CG  1 
ATOM   2978  C CD1 . LEU A 1 461 ? 128.480 87.706  130.208 1.00 51.91  ? 461 LEU A CD1 1 
ATOM   2979  C CD2 . LEU A 1 461 ? 130.433 87.191  131.617 1.00 53.10  ? 461 LEU A CD2 1 
ATOM   2980  N N   . PHE A 1 462 ? 130.373 92.688  132.493 1.00 50.24  ? 462 PHE A N   1 
ATOM   2981  C CA  . PHE A 1 462 ? 130.684 94.100  132.244 1.00 51.06  ? 462 PHE A CA  1 
ATOM   2982  C C   . PHE A 1 462 ? 130.736 94.896  133.558 1.00 49.29  ? 462 PHE A C   1 
ATOM   2983  O O   . PHE A 1 462 ? 130.384 96.076  133.619 1.00 51.17  ? 462 PHE A O   1 
ATOM   2984  C CB  . PHE A 1 462 ? 129.687 94.673  131.219 1.00 49.11  ? 462 PHE A CB  1 
ATOM   2985  C CG  . PHE A 1 462 ? 129.793 94.032  129.851 1.00 46.83  ? 462 PHE A CG  1 
ATOM   2986  C CD1 . PHE A 1 462 ? 130.709 94.532  128.911 1.00 47.83  ? 462 PHE A CD1 1 
ATOM   2987  C CD2 . PHE A 1 462 ? 129.003 92.914  129.527 1.00 48.81  ? 462 PHE A CD2 1 
ATOM   2988  C CE1 . PHE A 1 462 ? 130.846 93.912  127.656 1.00 49.97  ? 462 PHE A CE1 1 
ATOM   2989  C CE2 . PHE A 1 462 ? 129.143 92.291  128.276 1.00 52.02  ? 462 PHE A CE2 1 
ATOM   2990  C CZ  . PHE A 1 462 ? 130.060 92.790  127.341 1.00 49.41  ? 462 PHE A CZ  1 
ATOM   2991  N N   . ILE A 1 463 ? 131.145 94.252  134.653 1.00 51.99  ? 463 ILE A N   1 
ATOM   2992  C CA  . ILE A 1 463 ? 130.939 94.797  135.996 1.00 56.47  ? 463 ILE A CA  1 
ATOM   2993  C C   . ILE A 1 463 ? 131.650 96.139  136.210 1.00 54.74  ? 463 ILE A C   1 
ATOM   2994  O O   . ILE A 1 463 ? 131.025 97.061  136.723 1.00 54.98  ? 463 ILE A O   1 
ATOM   2995  C CB  . ILE A 1 463 ? 131.266 93.740  137.069 1.00 54.84  ? 463 ILE A CB  1 
ATOM   2996  C CG1 . ILE A 1 463 ? 130.699 94.186  138.430 1.00 53.67  ? 463 ILE A CG1 1 
ATOM   2997  C CG2 . ILE A 1 463 ? 132.762 93.410  137.168 1.00 54.74  ? 463 ILE A CG2 1 
ATOM   2998  C CD1 . ILE A 1 463 ? 130.582 93.053  139.452 1.00 54.57  ? 463 ILE A CD1 1 
ATOM   2999  N N   . TRP A 1 464 ? 132.880 96.302  135.717 1.00 60.40  ? 464 TRP A N   1 
ATOM   3000  C CA  . TRP A 1 464 ? 133.670 97.534  135.836 1.00 58.36  ? 464 TRP A CA  1 
ATOM   3001  C C   . TRP A 1 464 ? 133.061 98.764  135.142 1.00 60.81  ? 464 TRP A C   1 
ATOM   3002  O O   . TRP A 1 464 ? 133.473 99.890  135.417 1.00 61.27  ? 464 TRP A O   1 
ATOM   3003  C CB  . TRP A 1 464 ? 135.060 97.268  135.268 1.00 55.43  ? 464 TRP A CB  1 
ATOM   3004  N N   . ILE A 1 465 ? 132.072 98.563  134.266 1.00 62.50  ? 465 ILE A N   1 
ATOM   3005  C CA  . ILE A 1 465 ? 131.267 99.631  133.657 1.00 61.57  ? 465 ILE A CA  1 
ATOM   3006  C C   . ILE A 1 465 ? 129.803 99.640  134.136 1.00 59.78  ? 465 ILE A C   1 
ATOM   3007  O O   . ILE A 1 465 ? 129.151 100.675 134.086 1.00 60.51  ? 465 ILE A O   1 
ATOM   3008  C CB  . ILE A 1 465 ? 131.426 99.629  132.119 1.00 60.68  ? 465 ILE A CB  1 
ATOM   3009  C CG1 . ILE A 1 465 ? 130.876 98.371  131.431 1.00 58.73  ? 465 ILE A CG1 1 
ATOM   3010  C CG2 . ILE A 1 465 ? 132.898 99.893  131.762 1.00 59.27  ? 465 ILE A CG2 1 
ATOM   3011  C CD1 . ILE A 1 465 ? 130.862 98.475  129.908 1.00 49.76  ? 465 ILE A CD1 1 
ATOM   3012  N N   . SER A 1 466 ? 129.292 98.550  134.719 1.00 57.90  ? 466 SER A N   1 
ATOM   3013  C CA  . SER A 1 466 ? 127.926 98.445  135.270 1.00 60.94  ? 466 SER A CA  1 
ATOM   3014  C C   . SER A 1 466 ? 127.582 99.445  136.394 1.00 61.67  ? 466 SER A C   1 
ATOM   3015  O O   . SER A 1 466 ? 126.405 99.602  136.738 1.00 58.77  ? 466 SER A O   1 
ATOM   3016  C CB  . SER A 1 466 ? 127.697 97.034  135.808 1.00 59.24  ? 466 SER A CB  1 
ATOM   3017  O OG  . SER A 1 466 ? 128.355 96.845  137.046 1.00 59.01  ? 466 SER A OG  1 
ATOM   3018  N N   . PHE A 1 467 ? 128.592 100.108 136.964 1.00 64.14  ? 467 PHE A N   1 
ATOM   3019  C CA  . PHE A 1 467 ? 128.478 101.129 138.008 1.00 63.38  ? 467 PHE A CA  1 
ATOM   3020  C C   . PHE A 1 467 ? 129.065 102.502 137.607 1.00 64.85  ? 467 PHE A C   1 
ATOM   3021  O O   . PHE A 1 467 ? 129.096 103.407 138.437 1.00 66.48  ? 467 PHE A O   1 
ATOM   3022  C CB  . PHE A 1 467 ? 129.084 100.588 139.307 1.00 61.77  ? 467 PHE A CB  1 
ATOM   3023  C CG  . PHE A 1 467 ? 130.544 100.187 139.244 1.00 63.94  ? 467 PHE A CG  1 
ATOM   3024  C CD1 . PHE A 1 467 ? 131.553 101.167 139.245 1.00 65.46  ? 467 PHE A CD1 1 
ATOM   3025  C CD2 . PHE A 1 467 ? 130.903 98.828  139.275 1.00 61.80  ? 467 PHE A CD2 1 
ATOM   3026  C CE1 . PHE A 1 467 ? 132.905 100.791 139.274 1.00 65.01  ? 467 PHE A CE1 1 
ATOM   3027  C CE2 . PHE A 1 467 ? 132.251 98.451  139.315 1.00 63.57  ? 467 PHE A CE2 1 
ATOM   3028  C CZ  . PHE A 1 467 ? 133.255 99.431  139.311 1.00 62.69  ? 467 PHE A CZ  1 
ATOM   3029  N N   . MET A 1 468 ? 129.569 102.695 136.381 1.00 63.70  ? 468 MET A N   1 
ATOM   3030  C CA  . MET A 1 468 ? 130.397 103.873 136.055 1.00 64.67  ? 468 MET A CA  1 
ATOM   3031  C C   . MET A 1 468 ? 129.620 105.200 136.060 1.00 67.25  ? 468 MET A C   1 
ATOM   3032  O O   . MET A 1 468 ? 130.089 106.187 136.618 1.00 65.80  ? 468 MET A O   1 
ATOM   3033  C CB  . MET A 1 468 ? 131.142 103.651 134.729 1.00 65.54  ? 468 MET A CB  1 
ATOM   3034  C CG  . MET A 1 468 ? 130.266 103.710 133.479 1.00 66.00  ? 468 MET A CG  1 
ATOM   3035  S SD  . MET A 1 468 ? 131.107 103.150 131.981 1.00 77.49  ? 468 MET A SD  1 
ATOM   3036  C CE  . MET A 1 468 ? 129.656 102.906 130.933 1.00 61.89  ? 468 MET A CE  1 
ATOM   3037  N N   . ASP A 1 469 ? 128.408 105.212 135.498 1.00 60.77  ? 469 ASP A N   1 
ATOM   3038  C CA  . ASP A 1 469 ? 127.433 106.315 135.577 1.00 58.04  ? 469 ASP A CA  1 
ATOM   3039  C C   . ASP A 1 469 ? 126.255 105.964 136.506 1.00 52.71  ? 469 ASP A C   1 
ATOM   3040  O O   . ASP A 1 469 ? 125.274 106.703 136.606 1.00 53.60  ? 469 ASP A O   1 
ATOM   3041  C CB  . ASP A 1 469 ? 126.969 106.721 134.167 1.00 57.92  ? 469 ASP A CB  1 
ATOM   3042  C CG  . ASP A 1 469 ? 126.276 105.616 133.362 1.00 56.12  ? 469 ASP A CG  1 
ATOM   3043  O OD1 . ASP A 1 469 ? 126.148 104.475 133.847 1.00 57.25  ? 469 ASP A OD1 1 
ATOM   3044  O OD2 . ASP A 1 469 ? 125.890 105.891 132.209 1.00 59.63  ? 469 ASP A OD2 1 
ATOM   3045  N N   . SER A 1 470 ? 126.391 104.862 137.238 1.00 49.46  ? 470 SER A N   1 
ATOM   3046  C CA  . SER A 1 470 ? 125.379 104.138 138.013 1.00 49.45  ? 470 SER A CA  1 
ATOM   3047  C C   . SER A 1 470 ? 125.942 103.678 139.368 1.00 47.94  ? 470 SER A C   1 
ATOM   3048  O O   . SER A 1 470 ? 125.692 102.571 139.839 1.00 48.78  ? 470 SER A O   1 
ATOM   3049  C CB  . SER A 1 470 ? 124.861 102.975 137.163 1.00 49.69  ? 470 SER A CB  1 
ATOM   3050  O OG  . SER A 1 470 ? 125.965 102.257 136.661 1.00 54.89  ? 470 SER A OG  1 
ATOM   3051  N N   . TYR A 1 471 ? 126.714 104.551 140.024 1.00 39.18  ? 471 TYR A N   1 
ATOM   3052  C CA  . TYR A 1 471 ? 127.290 104.307 141.348 1.00 36.55  ? 471 TYR A CA  1 
ATOM   3053  C C   . TYR A 1 471 ? 126.235 104.110 142.442 1.00 32.12  ? 471 TYR A C   1 
ATOM   3054  O O   . TYR A 1 471 ? 126.551 103.579 143.497 1.00 37.34  ? 471 TYR A O   1 
ATOM   3055  C CB  . TYR A 1 471 ? 128.257 105.447 141.713 1.00 42.33  ? 471 TYR A CB  1 
ATOM   3056  C CG  . TYR A 1 471 ? 127.619 106.809 141.915 1.00 41.07  ? 471 TYR A CG  1 
ATOM   3057  C CD1 . TYR A 1 471 ? 126.710 107.007 142.971 1.00 40.91  ? 471 TYR A CD1 1 
ATOM   3058  C CD2 . TYR A 1 471 ? 127.950 107.890 141.081 1.00 44.05  ? 471 TYR A CD2 1 
ATOM   3059  C CE1 . TYR A 1 471 ? 126.043 108.224 143.130 1.00 39.87  ? 471 TYR A CE1 1 
ATOM   3060  C CE2 . TYR A 1 471 ? 127.344 109.146 141.292 1.00 46.66  ? 471 TYR A CE2 1 
ATOM   3061  C CZ  . TYR A 1 471 ? 126.361 109.303 142.295 1.00 45.92  ? 471 TYR A CZ  1 
ATOM   3062  O OH  . TYR A 1 471 ? 125.778 110.498 142.520 1.00 41.70  ? 471 TYR A OH  1 
ATOM   3063  N N   . PHE A 1 472 ? 124.973 104.494 142.230 1.00 29.54  ? 472 PHE A N   1 
ATOM   3064  C CA  . PHE A 1 472 ? 123.890 104.164 143.150 1.00 18.15  ? 472 PHE A CA  1 
ATOM   3065  C C   . PHE A 1 472 ? 123.713 102.661 143.319 1.00 18.77  ? 472 PHE A C   1 
ATOM   3066  O O   . PHE A 1 472 ? 123.278 102.238 144.376 1.00 37.88  ? 472 PHE A O   1 
ATOM   3067  C CB  . PHE A 1 472 ? 122.573 104.813 142.712 1.00 23.48  ? 472 PHE A CB  1 
ATOM   3068  C CG  . PHE A 1 472 ? 122.396 106.227 143.207 1.00 17.85  ? 472 PHE A CG  1 
ATOM   3069  C CD1 . PHE A 1 472 ? 122.302 106.461 144.588 1.00 20.34  ? 472 PHE A CD1 1 
ATOM   3070  C CD2 . PHE A 1 472 ? 122.294 107.299 142.307 1.00 21.46  ? 472 PHE A CD2 1 
ATOM   3071  C CE1 . PHE A 1 472 ? 122.133 107.764 145.070 1.00 17.43  ? 472 PHE A CE1 1 
ATOM   3072  C CE2 . PHE A 1 472 ? 122.094 108.600 142.792 1.00 19.70  ? 472 PHE A CE2 1 
ATOM   3073  C CZ  . PHE A 1 472 ? 122.015 108.827 144.173 1.00 22.00  ? 472 PHE A CZ  1 
ATOM   3074  N N   . GLU A 1 473 ? 124.104 101.822 142.367 1.00 28.40  ? 473 GLU A N   1 
ATOM   3075  C CA  . GLU A 1 473 ? 124.104 100.373 142.582 1.00 28.14  ? 473 GLU A CA  1 
ATOM   3076  C C   . GLU A 1 473 ? 125.180 99.950  143.603 1.00 29.94  ? 473 GLU A C   1 
ATOM   3077  O O   . GLU A 1 473 ? 124.969 99.064  144.421 1.00 34.40  ? 473 GLU A O   1 
ATOM   3078  C CB  . GLU A 1 473 ? 124.254 99.640  141.238 1.00 30.66  ? 473 GLU A CB  1 
ATOM   3079  C CG  . GLU A 1 473 ? 123.208 100.045 140.181 1.00 27.04  ? 473 GLU A CG  1 
ATOM   3080  C CD  . GLU A 1 473 ? 121.746 99.841  140.613 1.00 38.11  ? 473 GLU A CD  1 
ATOM   3081  O OE1 . GLU A 1 473 ? 121.360 98.740  141.051 1.00 39.24  ? 473 GLU A OE1 1 
ATOM   3082  O OE2 . GLU A 1 473 ? 120.958 100.814 140.521 1.00 47.14  ? 473 GLU A OE2 1 
ATOM   3083  N N   . ILE A 1 474 ? 126.324 100.635 143.658 1.00 34.79  ? 474 ILE A N   1 
ATOM   3084  C CA  . ILE A 1 474 ? 127.293 100.465 144.749 1.00 25.72  ? 474 ILE A CA  1 
ATOM   3085  C C   . ILE A 1 474 ? 126.731 101.021 146.066 1.00 27.11  ? 474 ILE A C   1 
ATOM   3086  O O   . ILE A 1 474 ? 126.814 100.351 147.088 1.00 37.13  ? 474 ILE A O   1 
ATOM   3087  C CB  . ILE A 1 474 ? 128.668 101.077 144.383 1.00 32.78  ? 474 ILE A CB  1 
ATOM   3088  C CG1 . ILE A 1 474 ? 129.293 100.262 143.235 1.00 32.02  ? 474 ILE A CG1 1 
ATOM   3089  C CG2 . ILE A 1 474 ? 129.609 101.112 145.601 1.00 28.37  ? 474 ILE A CG2 1 
ATOM   3090  C CD1 . ILE A 1 474 ? 130.627 100.793 142.712 1.00 36.89  ? 474 ILE A CD1 1 
ATOM   3091  N N   . LEU A 1 475 ? 126.140 102.219 146.075 1.00 25.68  ? 475 LEU A N   1 
ATOM   3092  C CA  . LEU A 1 475 ? 125.644 102.845 147.303 1.00 17.93  ? 475 LEU A CA  1 
ATOM   3093  C C   . LEU A 1 475 ? 124.433 102.127 147.915 1.00 19.70  ? 475 LEU A C   1 
ATOM   3094  O O   . LEU A 1 475 ? 124.346 102.026 149.136 1.00 30.74  ? 475 LEU A O   1 
ATOM   3095  C CB  . LEU A 1 475 ? 125.322 104.326 147.074 1.00 28.40  ? 475 LEU A CB  1 
ATOM   3096  C CG  . LEU A 1 475 ? 126.484 105.208 146.590 1.00 26.69  ? 475 LEU A CG  1 
ATOM   3097  C CD1 . LEU A 1 475 ? 125.973 106.623 146.366 1.00 29.50  ? 475 LEU A CD1 1 
ATOM   3098  C CD2 . LEU A 1 475 ? 127.658 105.268 147.557 1.00 17.91  ? 475 LEU A CD2 1 
ATOM   3099  N N   . PHE A 1 476 ? 123.513 101.584 147.116 1.00 13.50  ? 476 PHE A N   1 
ATOM   3100  C CA  . PHE A 1 476 ? 122.425 100.736 147.606 1.00 9.69   ? 476 PHE A CA  1 
ATOM   3101  C C   . PHE A 1 476 ? 122.940 99.398  148.146 1.00 11.47  ? 476 PHE A C   1 
ATOM   3102  O O   . PHE A 1 476 ? 122.467 98.964  149.191 1.00 22.61  ? 476 PHE A O   1 
ATOM   3103  C CB  . PHE A 1 476 ? 121.362 100.529 146.522 1.00 13.93  ? 476 PHE A CB  1 
ATOM   3104  C CG  . PHE A 1 476 ? 120.268 101.583 146.473 1.00 11.99  ? 476 PHE A CG  1 
ATOM   3105  C CD1 . PHE A 1 476 ? 120.487 102.838 145.883 1.00 13.79  ? 476 PHE A CD1 1 
ATOM   3106  C CD2 . PHE A 1 476 ? 119.000 101.291 147.003 1.00 9.56   ? 476 PHE A CD2 1 
ATOM   3107  C CE1 . PHE A 1 476 ? 119.446 103.770 145.780 1.00 10.13  ? 476 PHE A CE1 1 
ATOM   3108  C CE2 . PHE A 1 476 ? 117.961 102.226 146.910 1.00 13.54  ? 476 PHE A CE2 1 
ATOM   3109  C CZ  . PHE A 1 476 ? 118.180 103.462 146.289 1.00 9.53   ? 476 PHE A CZ  1 
ATOM   3110  N N   . LEU A 1 477 ? 123.940 98.772  147.511 1.00 24.46  ? 477 LEU A N   1 
ATOM   3111  C CA  . LEU A 1 477 ? 124.588 97.573  148.043 1.00 27.82  ? 477 LEU A CA  1 
ATOM   3112  C C   . LEU A 1 477 ? 125.284 97.842  149.382 1.00 22.59  ? 477 LEU A C   1 
ATOM   3113  O O   . LEU A 1 477 ? 125.085 97.102  150.341 1.00 31.90  ? 477 LEU A O   1 
ATOM   3114  C CB  . LEU A 1 477 ? 125.586 97.014  147.007 1.00 27.64  ? 477 LEU A CB  1 
ATOM   3115  C CG  . LEU A 1 477 ? 126.313 95.737  147.462 1.00 29.88  ? 477 LEU A CG  1 
ATOM   3116  C CD1 . LEU A 1 477 ? 125.384 94.537  147.503 1.00 27.58  ? 477 LEU A CD1 1 
ATOM   3117  C CD2 . LEU A 1 477 ? 127.463 95.417  146.522 1.00 29.74  ? 477 LEU A CD2 1 
ATOM   3118  N N   . LEU A 1 478 ? 126.070 98.917  149.469 1.00 25.68  ? 478 LEU A N   1 
ATOM   3119  C CA  . LEU A 1 478 ? 126.767 99.311  150.687 1.00 20.98  ? 478 LEU A CA  1 
ATOM   3120  C C   . LEU A 1 478 ? 125.794 99.624  151.828 1.00 18.21  ? 478 LEU A C   1 
ATOM   3121  O O   . LEU A 1 478 ? 126.002 99.163  152.945 1.00 31.35  ? 478 LEU A O   1 
ATOM   3122  C CB  . LEU A 1 478 ? 127.709 100.476 150.363 1.00 28.45  ? 478 LEU A CB  1 
ATOM   3123  C CG  . LEU A 1 478 ? 128.518 100.994 151.559 1.00 36.43  ? 478 LEU A CG  1 
ATOM   3124  C CD1 . LEU A 1 478 ? 129.469 99.946  152.118 1.00 27.98  ? 478 LEU A CD1 1 
ATOM   3125  C CD2 . LEU A 1 478 ? 129.314 102.222 151.142 1.00 27.32  ? 478 LEU A CD2 1 
ATOM   3126  N N   . GLN A 1 479 ? 124.693 100.332 151.572 1.00 17.57  ? 479 GLN A N   1 
ATOM   3127  C CA  . GLN A 1 479 ? 123.676 100.604 152.588 1.00 17.28  ? 479 GLN A CA  1 
ATOM   3128  C C   . GLN A 1 479 ? 123.042 99.328  153.133 1.00 20.46  ? 479 GLN A C   1 
ATOM   3129  O O   . GLN A 1 479 ? 122.875 99.187  154.340 1.00 28.93  ? 479 GLN A O   1 
ATOM   3130  C CB  . GLN A 1 479 ? 122.607 101.529 151.996 1.00 19.84  ? 479 GLN A CB  1 
ATOM   3131  C CG  . GLN A 1 479 ? 121.781 102.278 153.048 1.00 19.43  ? 479 GLN A CG  1 
ATOM   3132  C CD  . GLN A 1 479 ? 120.535 101.593 153.608 1.00 21.70  ? 479 GLN A CD  1 
ATOM   3133  O OE1 . GLN A 1 479 ? 119.980 100.648 153.074 1.00 23.79  ? 479 GLN A OE1 1 
ATOM   3134  N NE2 . GLN A 1 479 ? 120.015 102.102 154.696 1.00 30.31  ? 479 GLN A NE2 1 
ATOM   3135  N N   . ALA A 1 480 ? 122.730 98.371  152.263 1.00 28.61  ? 480 ALA A N   1 
ATOM   3136  C CA  . ALA A 1 480 ? 122.166 97.091  152.638 1.00 24.18  ? 480 ALA A CA  1 
ATOM   3137  C C   . ALA A 1 480 ? 123.155 96.228  153.442 1.00 24.10  ? 480 ALA A C   1 
ATOM   3138  O O   . ALA A 1 480 ? 122.780 95.673  154.470 1.00 27.06  ? 480 ALA A O   1 
ATOM   3139  C CB  . ALA A 1 480 ? 121.705 96.414  151.358 1.00 29.88  ? 480 ALA A CB  1 
ATOM   3140  N N   . LEU A 1 481 ? 124.435 96.174  153.050 1.00 24.01  ? 481 LEU A N   1 
ATOM   3141  C CA  . LEU A 1 481 ? 125.495 95.522  153.825 1.00 28.63  ? 481 LEU A CA  1 
ATOM   3142  C C   . LEU A 1 481 ? 125.645 96.127  155.225 1.00 29.78  ? 481 LEU A C   1 
ATOM   3143  O O   . LEU A 1 481 ? 125.564 95.402  156.212 1.00 33.93  ? 481 LEU A O   1 
ATOM   3144  C CB  . LEU A 1 481 ? 126.839 95.616  153.081 1.00 31.27  ? 481 LEU A CB  1 
ATOM   3145  C CG  . LEU A 1 481 ? 127.000 94.638  151.911 1.00 35.54  ? 481 LEU A CG  1 
ATOM   3146  C CD1 . LEU A 1 481 ? 128.274 94.971  151.141 1.00 35.61  ? 481 LEU A CD1 1 
ATOM   3147  C CD2 . LEU A 1 481 ? 127.110 93.195  152.399 1.00 31.02  ? 481 LEU A CD2 1 
ATOM   3148  N N   . LEU A 1 482 ? 125.824 97.445  155.327 1.00 33.85  ? 482 LEU A N   1 
ATOM   3149  C CA  . LEU A 1 482 ? 125.971 98.133  156.611 1.00 26.18  ? 482 LEU A CA  1 
ATOM   3150  C C   . LEU A 1 482 ? 124.722 97.979  157.486 1.00 19.12  ? 482 LEU A C   1 
ATOM   3151  O O   . LEU A 1 482 ? 124.838 97.838  158.700 1.00 32.65  ? 482 LEU A O   1 
ATOM   3152  C CB  . LEU A 1 482 ? 126.303 99.610  156.373 1.00 30.20  ? 482 LEU A CB  1 
ATOM   3153  C CG  . LEU A 1 482 ? 127.644 99.889  155.684 1.00 30.29  ? 482 LEU A CG  1 
ATOM   3154  C CD1 . LEU A 1 482 ? 127.721 101.376 155.357 1.00 28.26  ? 482 LEU A CD1 1 
ATOM   3155  C CD2 . LEU A 1 482 ? 128.837 99.528  156.555 1.00 29.62  ? 482 LEU A CD2 1 
ATOM   3156  N N   . THR A 1 483 ? 123.535 97.904  156.884 1.00 25.03  ? 483 THR A N   1 
ATOM   3157  C CA  . THR A 1 483 ? 122.295 97.609  157.600 1.00 25.83  ? 483 THR A CA  1 
ATOM   3158  C C   . THR A 1 483 ? 122.311 96.210  158.196 1.00 30.04  ? 483 THR A C   1 
ATOM   3159  O O   . THR A 1 483 ? 122.104 96.072  159.395 1.00 40.80  ? 483 THR A O   1 
ATOM   3160  C CB  . THR A 1 483 ? 121.072 97.767  156.698 1.00 27.38  ? 483 THR A CB  1 
ATOM   3161  O OG1 . THR A 1 483 ? 121.025 99.077  156.220 1.00 38.10  ? 483 THR A OG1 1 
ATOM   3162  C CG2 . THR A 1 483 ? 119.774 97.514  157.449 1.00 29.80  ? 483 THR A CG2 1 
ATOM   3163  N N   . VAL A 1 484 ? 122.603 95.172  157.411 1.00 40.82  ? 484 VAL A N   1 
ATOM   3164  C CA  . VAL A 1 484 ? 122.667 93.791  157.901 1.00 37.48  ? 484 VAL A CA  1 
ATOM   3165  C C   . VAL A 1 484 ? 123.770 93.634  158.947 1.00 37.25  ? 484 VAL A C   1 
ATOM   3166  O O   . VAL A 1 484 ? 123.506 93.112  160.025 1.00 46.32  ? 484 VAL A O   1 
ATOM   3167  C CB  . VAL A 1 484 ? 122.810 92.804  156.725 1.00 37.10  ? 484 VAL A CB  1 
ATOM   3168  C CG1 . VAL A 1 484 ? 123.024 91.363  157.186 1.00 39.12  ? 484 VAL A CG1 1 
ATOM   3169  C CG2 . VAL A 1 484 ? 121.540 92.820  155.876 1.00 37.14  ? 484 VAL A CG2 1 
ATOM   3170  N N   . LEU A 1 485 ? 124.963 94.179  158.712 1.00 38.90  ? 485 LEU A N   1 
ATOM   3171  C CA  . LEU A 1 485 ? 126.042 94.186  159.698 1.00 39.37  ? 485 LEU A CA  1 
ATOM   3172  C C   . LEU A 1 485 ? 125.634 94.891  160.995 1.00 41.24  ? 485 LEU A C   1 
ATOM   3173  O O   . LEU A 1 485 ? 125.884 94.354  162.065 1.00 44.83  ? 485 LEU A O   1 
ATOM   3174  C CB  . LEU A 1 485 ? 127.308 94.816  159.102 1.00 37.67  ? 485 LEU A CB  1 
ATOM   3175  C CG  . LEU A 1 485 ? 127.991 93.941  158.043 1.00 48.38  ? 485 LEU A CG  1 
ATOM   3176  C CD1 . LEU A 1 485 ? 129.039 94.760  157.296 1.00 45.48  ? 485 LEU A CD1 1 
ATOM   3177  C CD2 . LEU A 1 485 ? 128.670 92.726  158.672 1.00 46.90  ? 485 LEU A CD2 1 
ATOM   3178  N N   . SER A 1 486 ? 124.947 96.033  160.943 1.00 40.41  ? 486 SER A N   1 
ATOM   3179  C CA  . SER A 1 486 ? 124.471 96.704  162.160 1.00 34.06  ? 486 SER A CA  1 
ATOM   3180  C C   . SER A 1 486 ? 123.514 95.829  162.972 1.00 40.08  ? 486 SER A C   1 
ATOM   3181  O O   . SER A 1 486 ? 123.600 95.811  164.192 1.00 47.40  ? 486 SER A O   1 
ATOM   3182  C CB  . SER A 1 486 ? 123.830 98.055  161.843 1.00 34.81  ? 486 SER A CB  1 
ATOM   3183  O OG  . SER A 1 486 ? 122.544 97.923  161.287 1.00 41.13  ? 486 SER A OG  1 
ATOM   3184  N N   . GLN A 1 487 ? 122.652 95.037  162.332 1.00 45.19  ? 487 GLN A N   1 
ATOM   3185  C CA  . GLN A 1 487 ? 121.754 94.114  163.029 1.00 44.12  ? 487 GLN A CA  1 
ATOM   3186  C C   . GLN A 1 487 ? 122.484 92.889  163.593 1.00 44.29  ? 487 GLN A C   1 
ATOM   3187  O O   . GLN A 1 487 ? 122.187 92.465  164.705 1.00 47.22  ? 487 GLN A O   1 
ATOM   3188  C CB  . GLN A 1 487 ? 120.614 93.694  162.097 1.00 44.22  ? 487 GLN A CB  1 
ATOM   3189  C CG  . GLN A 1 487 ? 119.762 94.879  161.626 1.00 43.31  ? 487 GLN A CG  1 
ATOM   3190  C CD  . GLN A 1 487 ? 119.248 95.739  162.769 1.00 45.13  ? 487 GLN A CD  1 
ATOM   3191  O OE1 . GLN A 1 487 ? 118.646 95.261  163.716 1.00 51.78  ? 487 GLN A OE1 1 
ATOM   3192  N NE2 . GLN A 1 487 ? 119.481 97.032  162.741 1.00 45.83  ? 487 GLN A NE2 1 
ATOM   3193  N N   . VAL A 1 488 ? 123.501 92.371  162.898 1.00 48.48  ? 488 VAL A N   1 
ATOM   3194  C CA  . VAL A 1 488 ? 124.393 91.326  163.424 1.00 49.13  ? 488 VAL A CA  1 
ATOM   3195  C C   . VAL A 1 488 ? 125.156 91.822  164.656 1.00 51.61  ? 488 VAL A C   1 
ATOM   3196  O O   . VAL A 1 488 ? 125.133 91.169  165.696 1.00 53.86  ? 488 VAL A O   1 
ATOM   3197  C CB  . VAL A 1 488 ? 125.355 90.837  162.323 1.00 48.60  ? 488 VAL A CB  1 
ATOM   3198  C CG1 . VAL A 1 488 ? 126.435 89.893  162.852 1.00 50.61  ? 488 VAL A CG1 1 
ATOM   3199  C CG2 . VAL A 1 488 ? 124.583 90.091  161.231 1.00 45.73  ? 488 VAL A CG2 1 
ATOM   3200  N N   . LEU A 1 489 ? 125.768 93.008  164.598 1.00 49.63  ? 489 LEU A N   1 
ATOM   3201  C CA  . LEU A 1 489 ? 126.459 93.598  165.747 1.00 44.98  ? 489 LEU A CA  1 
ATOM   3202  C C   . LEU A 1 489 ? 125.502 93.898  166.909 1.00 44.76  ? 489 LEU A C   1 
ATOM   3203  O O   . LEU A 1 489 ? 125.877 93.724  168.066 1.00 53.42  ? 489 LEU A O   1 
ATOM   3204  C CB  . LEU A 1 489 ? 127.209 94.872  165.324 1.00 48.57  ? 489 LEU A CB  1 
ATOM   3205  C CG  . LEU A 1 489 ? 128.387 94.705  164.350 1.00 47.46  ? 489 LEU A CG  1 
ATOM   3206  C CD1 . LEU A 1 489 ? 129.283 95.937  164.457 1.00 45.55  ? 489 LEU A CD1 1 
ATOM   3207  C CD2 . LEU A 1 489 ? 129.257 93.478  164.617 1.00 47.28  ? 489 LEU A CD2 1 
ATOM   3208  N N   . ARG A 1 490 ? 124.257 94.292  166.629 1.00 42.08  ? 490 ARG A N   1 
ATOM   3209  C CA  . ARG A 1 490 ? 123.216 94.487  167.645 1.00 47.42  ? 490 ARG A CA  1 
ATOM   3210  C C   . ARG A 1 490 ? 122.838 93.176  168.340 1.00 52.44  ? 490 ARG A C   1 
ATOM   3211  O O   . ARG A 1 490 ? 122.703 93.164  169.559 1.00 58.06  ? 490 ARG A O   1 
ATOM   3212  C CB  . ARG A 1 490 ? 122.011 95.161  166.984 1.00 49.96  ? 490 ARG A CB  1 
ATOM   3213  C CG  . ARG A 1 490 ? 120.940 95.553  167.995 1.00 44.81  ? 490 ARG A CG  1 
ATOM   3214  C CD  . ARG A 1 490 ? 119.719 96.113  167.272 1.00 50.55  ? 490 ARG A CD  1 
ATOM   3215  N NE  . ARG A 1 490 ? 118.571 96.220  168.187 1.00 57.82  ? 490 ARG A NE  1 
ATOM   3216  C CZ  . ARG A 1 490 ? 117.738 95.262  168.543 1.00 54.27  ? 490 ARG A CZ  1 
ATOM   3217  N NH1 . ARG A 1 490 ? 116.804 95.490  169.412 1.00 53.12  ? 490 ARG A NH1 1 
ATOM   3218  N NH2 . ARG A 1 490 ? 117.817 94.062  168.066 1.00 49.85  ? 490 ARG A NH2 1 
ATOM   3219  N N   . PHE A 1 491 ? 122.726 92.060  167.614 1.00 57.86  ? 491 PHE A N   1 
ATOM   3220  C CA  . PHE A 1 491 ? 122.532 90.733  168.225 1.00 57.35  ? 491 PHE A CA  1 
ATOM   3221  C C   . PHE A 1 491 ? 123.747 90.272  169.054 1.00 60.68  ? 491 PHE A C   1 
ATOM   3222  O O   . PHE A 1 491 ? 123.570 89.663  170.107 1.00 62.21  ? 491 PHE A O   1 
ATOM   3223  N N   . MET A 1 492 ? 124.971 90.611  168.643 1.00 59.42  ? 492 MET A N   1 
ATOM   3224  C CA  . MET A 1 492 ? 126.190 90.428  169.450 1.00 58.85  ? 492 MET A CA  1 
ATOM   3225  C C   . MET A 1 492 ? 126.308 91.395  170.645 1.00 60.65  ? 492 MET A C   1 
ATOM   3226  O O   . MET A 1 492 ? 127.231 91.266  171.446 1.00 63.29  ? 492 MET A O   1 
ATOM   3227  C CB  . MET A 1 492 ? 127.431 90.563  168.557 1.00 59.12  ? 492 MET A CB  1 
ATOM   3228  C CG  . MET A 1 492 ? 127.535 89.465  167.501 1.00 61.62  ? 492 MET A CG  1 
ATOM   3229  S SD  . MET A 1 492 ? 128.987 89.665  166.441 1.00 73.56  ? 492 MET A SD  1 
ATOM   3230  C CE  . MET A 1 492 ? 128.791 88.198  165.407 1.00 60.99  ? 492 MET A CE  1 
ATOM   3231  N N   . GLU A 1 493 ? 125.393 92.356  170.781 1.00 60.82  ? 493 GLU A N   1 
ATOM   3232  C CA  . GLU A 1 493 ? 125.375 93.390  171.818 1.00 61.95  ? 493 GLU A CA  1 
ATOM   3233  C C   . GLU A 1 493 ? 126.627 94.289  171.902 1.00 61.67  ? 493 GLU A C   1 
ATOM   3234  O O   . GLU A 1 493 ? 126.870 94.901  172.942 1.00 62.54  ? 493 GLU A O   1 
ATOM   3235  C CB  . GLU A 1 493 ? 125.012 92.750  173.157 1.00 59.14  ? 493 GLU A CB  1 
ATOM   3236  N N   . THR A 1 494 ? 127.434 94.398  170.840 1.00 56.06  ? 494 THR A N   1 
ATOM   3237  C CA  . THR A 1 494 ? 128.597 95.310  170.818 1.00 58.27  ? 494 THR A CA  1 
ATOM   3238  C C   . THR A 1 494 ? 128.175 96.754  170.543 1.00 56.70  ? 494 THR A C   1 
ATOM   3239  O O   . THR A 1 494 ? 127.260 96.992  169.759 1.00 59.02  ? 494 THR A O   1 
ATOM   3240  C CB  . THR A 1 494 ? 129.687 94.831  169.847 1.00 57.68  ? 494 THR A CB  1 
ATOM   3241  O OG1 . THR A 1 494 ? 130.834 95.636  169.975 1.00 58.53  ? 494 THR A OG1 1 
ATOM   3242  C CG2 . THR A 1 494 ? 129.308 94.878  168.372 1.00 54.73  ? 494 THR A CG2 1 
ATOM   3243  N N   . GLU A 1 495 ? 128.828 97.749  171.151 1.00 57.16  ? 495 GLU A N   1 
ATOM   3244  C CA  . GLU A 1 495 ? 128.455 99.167  171.002 1.00 56.33  ? 495 GLU A CA  1 
ATOM   3245  C C   . GLU A 1 495 ? 128.555 99.680  169.555 1.00 56.47  ? 495 GLU A C   1 
ATOM   3246  O O   . GLU A 1 495 ? 127.803 100.563 169.145 1.00 59.53  ? 495 GLU A O   1 
ATOM   3247  C CB  . GLU A 1 495 ? 129.307 100.028 171.948 1.00 57.57  ? 495 GLU A CB  1 
ATOM   3248  C CG  . GLU A 1 495 ? 130.784 100.151 171.531 1.00 58.05  ? 495 GLU A CG  1 
ATOM   3249  C CD  . GLU A 1 495 ? 131.620 100.957 172.534 1.00 60.80  ? 495 GLU A CD  1 
ATOM   3250  O OE1 . GLU A 1 495 ? 131.127 101.954 173.100 1.00 58.61  ? 495 GLU A OE1 1 
ATOM   3251  O OE2 . GLU A 1 495 ? 132.797 100.609 172.770 1.00 62.34  ? 495 GLU A OE2 1 
ATOM   3252  N N   . TRP A 1 496 ? 129.443 99.093  168.754 1.00 48.41  ? 496 TRP A N   1 
ATOM   3253  C CA  . TRP A 1 496 ? 129.716 99.494  167.376 1.00 47.81  ? 496 TRP A CA  1 
ATOM   3254  C C   . TRP A 1 496 ? 128.564 99.243  166.401 1.00 50.21  ? 496 TRP A C   1 
ATOM   3255  O O   . TRP A 1 496 ? 128.627 99.684  165.255 1.00 51.33  ? 496 TRP A O   1 
ATOM   3256  C CB  . TRP A 1 496 ? 131.028 98.845  166.923 1.00 48.86  ? 496 TRP A CB  1 
ATOM   3257  C CG  . TRP A 1 496 ? 132.181 99.343  167.729 1.00 54.42  ? 496 TRP A CG  1 
ATOM   3258  C CD1 . TRP A 1 496 ? 132.771 98.693  168.757 1.00 52.13  ? 496 TRP A CD1 1 
ATOM   3259  C CD2 . TRP A 1 496 ? 132.789 100.668 167.686 1.00 57.48  ? 496 TRP A CD2 1 
ATOM   3260  N NE1 . TRP A 1 496 ? 133.674 99.538  169.372 1.00 52.46  ? 496 TRP A NE1 1 
ATOM   3261  C CE2 . TRP A 1 496 ? 133.700 100.779 168.774 1.00 56.74  ? 496 TRP A CE2 1 
ATOM   3262  C CE3 . TRP A 1 496 ? 132.630 101.801 166.858 1.00 51.11  ? 496 TRP A CE3 1 
ATOM   3263  C CZ2 . TRP A 1 496 ? 134.389 101.965 169.052 1.00 53.74  ? 496 TRP A CZ2 1 
ATOM   3264  C CZ3 . TRP A 1 496 ? 133.317 102.998 167.126 1.00 52.30  ? 496 TRP A CZ3 1 
ATOM   3265  C CH2 . TRP A 1 496 ? 134.186 103.084 168.229 1.00 53.97  ? 496 TRP A CH2 1 
ATOM   3266  N N   . TYR A 1 497 ? 127.479 98.601  166.838 1.00 44.51  ? 497 TYR A N   1 
ATOM   3267  C CA  . TYR A 1 497 ? 126.264 98.533  166.038 1.00 41.00  ? 497 TYR A CA  1 
ATOM   3268  C C   . TYR A 1 497 ? 125.694 99.928  165.744 1.00 41.34  ? 497 TYR A C   1 
ATOM   3269  O O   . TYR A 1 497 ? 125.202 100.150 164.641 1.00 44.27  ? 497 TYR A O   1 
ATOM   3270  C CB  . TYR A 1 497 ? 125.236 97.620  166.720 1.00 40.74  ? 497 TYR A CB  1 
ATOM   3271  C CG  . TYR A 1 497 ? 124.169 98.323  167.525 1.00 38.88  ? 497 TYR A CG  1 
ATOM   3272  C CD1 . TYR A 1 497 ? 122.985 98.766  166.902 1.00 40.78  ? 497 TYR A CD1 1 
ATOM   3273  C CD2 . TYR A 1 497 ? 124.383 98.579  168.885 1.00 39.73  ? 497 TYR A CD2 1 
ATOM   3274  C CE1 . TYR A 1 497 ? 122.024 99.481  167.642 1.00 38.91  ? 497 TYR A CE1 1 
ATOM   3275  C CE2 . TYR A 1 497 ? 123.429 99.286  169.626 1.00 44.05  ? 497 TYR A CE2 1 
ATOM   3276  C CZ  . TYR A 1 497 ? 122.254 99.747  169.008 1.00 45.76  ? 497 TYR A CZ  1 
ATOM   3277  O OH  . TYR A 1 497 ? 121.350 100.437 169.741 1.00 48.24  ? 497 TYR A OH  1 
ATOM   3278  N N   . LEU A 1 498 ? 125.786 100.876 166.684 1.00 35.89  ? 498 LEU A N   1 
ATOM   3279  C CA  . LEU A 1 498 ? 125.137 102.179 166.555 1.00 32.29  ? 498 LEU A CA  1 
ATOM   3280  C C   . LEU A 1 498 ? 125.804 103.083 165.498 1.00 34.76  ? 498 LEU A C   1 
ATOM   3281  O O   . LEU A 1 498 ? 125.087 103.586 164.638 1.00 33.51  ? 498 LEU A O   1 
ATOM   3282  C CB  . LEU A 1 498 ? 124.950 102.822 167.943 1.00 34.90  ? 498 LEU A CB  1 
ATOM   3283  C CG  . LEU A 1 498 ? 124.164 104.142 167.913 1.00 36.78  ? 498 LEU A CG  1 
ATOM   3284  C CD1 . LEU A 1 498 ? 122.702 103.918 167.542 1.00 35.26  ? 498 LEU A CD1 1 
ATOM   3285  C CD2 . LEU A 1 498 ? 124.211 104.819 169.276 1.00 34.72  ? 498 LEU A CD2 1 
ATOM   3286  N N   . PRO A 1 499 ? 127.139 103.236 165.441 1.00 34.18  ? 499 PRO A N   1 
ATOM   3287  C CA  . PRO A 1 499 ? 127.824 103.825 164.291 1.00 30.00  ? 499 PRO A CA  1 
ATOM   3288  C C   . PRO A 1 499 ? 127.474 103.196 162.936 1.00 32.61  ? 499 PRO A C   1 
ATOM   3289  O O   . PRO A 1 499 ? 127.267 103.932 161.977 1.00 34.63  ? 499 PRO A O   1 
ATOM   3290  C CB  . PRO A 1 499 ? 129.314 103.670 164.593 1.00 31.86  ? 499 PRO A CB  1 
ATOM   3291  C CG  . PRO A 1 499 ? 129.357 103.740 166.107 1.00 28.66  ? 499 PRO A CG  1 
ATOM   3292  C CD  . PRO A 1 499 ? 128.082 103.030 166.526 1.00 26.88  ? 499 PRO A CD  1 
ATOM   3293  N N   . LEU A 1 500 ? 127.353 101.865 162.826 1.00 31.27  ? 500 LEU A N   1 
ATOM   3294  C CA  . LEU A 1 500 ? 126.943 101.220 161.571 1.00 28.70  ? 500 LEU A CA  1 
ATOM   3295  C C   . LEU A 1 500 ? 125.482 101.500 161.214 1.00 28.93  ? 500 LEU A C   1 
ATOM   3296  O O   . LEU A 1 500 ? 125.186 101.767 160.053 1.00 35.11  ? 500 LEU A O   1 
ATOM   3297  C CB  . LEU A 1 500 ? 127.164 99.699  161.611 1.00 34.27  ? 500 LEU A CB  1 
ATOM   3298  C CG  . LEU A 1 500 ? 128.612 99.206  161.695 1.00 37.55  ? 500 LEU A CG  1 
ATOM   3299  C CD1 . LEU A 1 500 ? 128.604 97.698  161.452 1.00 38.08  ? 500 LEU A CD1 1 
ATOM   3300  C CD2 . LEU A 1 500 ? 129.518 99.835  160.646 1.00 33.87  ? 500 LEU A CD2 1 
ATOM   3301  N N   . LEU A 1 501 ? 124.567 101.471 162.181 1.00 20.11  ? 501 LEU A N   1 
ATOM   3302  C CA  . LEU A 1 501 ? 123.160 101.806 161.973 1.00 22.94  ? 501 LEU A CA  1 
ATOM   3303  C C   . LEU A 1 501 ? 123.004 103.256 161.508 1.00 22.34  ? 501 LEU A C   1 
ATOM   3304  O O   . LEU A 1 501 ? 122.272 103.539 160.566 1.00 31.03  ? 501 LEU A O   1 
ATOM   3305  C CB  . LEU A 1 501 ? 122.393 101.552 163.282 1.00 23.64  ? 501 LEU A CB  1 
ATOM   3306  C CG  . LEU A 1 501 ? 120.876 101.771 163.167 1.00 24.14  ? 501 LEU A CG  1 
ATOM   3307  C CD1 . LEU A 1 501 ? 120.216 100.598 162.449 1.00 26.78  ? 501 LEU A CD1 1 
ATOM   3308  C CD2 . LEU A 1 501 ? 120.251 101.906 164.546 1.00 27.36  ? 501 LEU A CD2 1 
ATOM   3309  N N   . VAL A 1 502 ? 123.729 104.175 162.129 1.00 32.50  ? 502 VAL A N   1 
ATOM   3310  C CA  . VAL A 1 502 ? 123.728 105.601 161.800 1.00 26.40  ? 502 VAL A CA  1 
ATOM   3311  C C   . VAL A 1 502 ? 124.400 105.884 160.451 1.00 22.48  ? 502 VAL A C   1 
ATOM   3312  O O   . VAL A 1 502 ? 123.877 106.675 159.676 1.00 33.73  ? 502 VAL A O   1 
ATOM   3313  C CB  . VAL A 1 502 ? 124.342 106.383 162.975 1.00 27.86  ? 502 VAL A CB  1 
ATOM   3314  C CG1 . VAL A 1 502 ? 124.603 107.837 162.635 1.00 25.75  ? 502 VAL A CG1 1 
ATOM   3315  C CG2 . VAL A 1 502 ? 123.369 106.371 164.159 1.00 19.38  ? 502 VAL A CG2 1 
ATOM   3316  N N   . LEU A 1 503 ? 125.488 105.204 160.093 1.00 17.67  ? 503 LEU A N   1 
ATOM   3317  C CA  . LEU A 1 503 ? 126.082 105.319 158.758 1.00 22.29  ? 503 LEU A CA  1 
ATOM   3318  C C   . LEU A 1 503 ? 125.147 104.771 157.665 1.00 24.64  ? 503 LEU A C   1 
ATOM   3319  O O   . LEU A 1 503 ? 125.005 105.379 156.608 1.00 33.37  ? 503 LEU A O   1 
ATOM   3320  C CB  . LEU A 1 503 ? 127.460 104.635 158.757 1.00 29.73  ? 503 LEU A CB  1 
ATOM   3321  C CG  . LEU A 1 503 ? 128.197 104.691 157.405 1.00 33.12  ? 503 LEU A CG  1 
ATOM   3322  C CD1 . LEU A 1 503 ? 128.472 106.113 156.928 1.00 31.91  ? 503 LEU A CD1 1 
ATOM   3323  C CD2 . LEU A 1 503 ? 129.525 103.952 157.514 1.00 27.39  ? 503 LEU A CD2 1 
ATOM   3324  N N   . SER A 1 504 ? 124.444 103.671 157.936 1.00 26.84  ? 504 SER A N   1 
ATOM   3325  C CA  . SER A 1 504 ? 123.406 103.116 157.060 1.00 18.01  ? 504 SER A CA  1 
ATOM   3326  C C   . SER A 1 504 ? 122.219 104.052 156.891 1.00 18.47  ? 504 SER A C   1 
ATOM   3327  O O   . SER A 1 504 ? 121.662 104.135 155.805 1.00 27.40  ? 504 SER A O   1 
ATOM   3328  C CB  . SER A 1 504 ? 122.852 101.815 157.634 1.00 22.38  ? 504 SER A CB  1 
ATOM   3329  O OG  . SER A 1 504 ? 123.882 100.916 157.908 1.00 35.72  ? 504 SER A OG  1 
ATOM   3330  N N   . LEU A 1 505 ? 121.818 104.762 157.941 1.00 18.08  ? 505 LEU A N   1 
ATOM   3331  C CA  . LEU A 1 505 ? 120.758 105.759 157.913 1.00 20.29  ? 505 LEU A CA  1 
ATOM   3332  C C   . LEU A 1 505 ? 121.118 106.954 157.020 1.00 18.80  ? 505 LEU A C   1 
ATOM   3333  O O   . LEU A 1 505 ? 120.335 107.308 156.145 1.00 26.87  ? 505 LEU A O   1 
ATOM   3334  C CB  . LEU A 1 505 ? 120.475 106.175 159.364 1.00 23.03  ? 505 LEU A CB  1 
ATOM   3335  C CG  . LEU A 1 505 ? 119.455 107.299 159.559 1.00 21.68  ? 505 LEU A CG  1 
ATOM   3336  C CD1 . LEU A 1 505 ? 118.041 106.820 159.279 1.00 15.78  ? 505 LEU A CD1 1 
ATOM   3337  C CD2 . LEU A 1 505 ? 119.541 107.783 161.000 1.00 18.06  ? 505 LEU A CD2 1 
ATOM   3338  N N   . VAL A 1 506 ? 122.303 107.546 157.190 1.00 19.36  ? 506 VAL A N   1 
ATOM   3339  C CA  . VAL A 1 506 ? 122.772 108.654 156.345 1.00 21.50  ? 506 VAL A CA  1 
ATOM   3340  C C   . VAL A 1 506 ? 122.841 108.209 154.891 1.00 18.10  ? 506 VAL A C   1 
ATOM   3341  O O   . VAL A 1 506 ? 122.251 108.837 154.018 1.00 22.74  ? 506 VAL A O   1 
ATOM   3342  C CB  . VAL A 1 506 ? 124.145 109.183 156.798 1.00 17.91  ? 506 VAL A CB  1 
ATOM   3343  C CG1 . VAL A 1 506 ? 124.704 110.253 155.861 1.00 21.90  ? 506 VAL A CG1 1 
ATOM   3344  C CG2 . VAL A 1 506 ? 124.064 109.817 158.174 1.00 18.27  ? 506 VAL A CG2 1 
ATOM   3345  N N   . LEU A 1 507 ? 123.504 107.082 154.632 1.00 17.51  ? 507 LEU A N   1 
ATOM   3346  C CA  . LEU A 1 507 ? 123.648 106.536 153.295 1.00 13.80  ? 507 LEU A CA  1 
ATOM   3347  C C   . LEU A 1 507 ? 122.294 106.197 152.653 1.00 8.21   ? 507 LEU A C   1 
ATOM   3348  O O   . LEU A 1 507 ? 122.104 106.424 151.470 1.00 30.62  ? 507 LEU A O   1 
ATOM   3349  C CB  . LEU A 1 507 ? 124.603 105.345 153.399 1.00 22.46  ? 507 LEU A CB  1 
ATOM   3350  C CG  . LEU A 1 507 ? 124.994 104.712 152.064 1.00 28.93  ? 507 LEU A CG  1 
ATOM   3351  C CD1 . LEU A 1 507 ? 125.656 105.689 151.105 1.00 28.20  ? 507 LEU A CD1 1 
ATOM   3352  C CD2 . LEU A 1 507 ? 125.976 103.584 152.335 1.00 27.25  ? 507 LEU A CD2 1 
ATOM   3353  N N   . GLY A 1 508 ? 121.310 105.752 153.433 1.00 7.75   ? 508 GLY A N   1 
ATOM   3354  C CA  . GLY A 1 508 ? 119.948 105.523 152.970 1.00 0.00   ? 508 GLY A CA  1 
ATOM   3355  C C   . GLY A 1 508 ? 119.167 106.781 152.603 1.00 9.08   ? 508 GLY A C   1 
ATOM   3356  O O   . GLY A 1 508 ? 118.397 106.760 151.650 1.00 22.83  ? 508 GLY A O   1 
ATOM   3357  N N   . TRP A 1 509 ? 119.376 107.914 153.267 1.00 22.55  ? 509 TRP A N   1 
ATOM   3358  C CA  . TRP A 1 509 ? 118.785 109.186 152.840 1.00 10.17  ? 509 TRP A CA  1 
ATOM   3359  C C   . TRP A 1 509 ? 119.432 109.736 151.568 1.00 10.41  ? 509 TRP A C   1 
ATOM   3360  O O   . TRP A 1 509 ? 118.731 110.213 150.691 1.00 23.34  ? 509 TRP A O   1 
ATOM   3361  C CB  . TRP A 1 509 ? 118.770 110.188 153.999 1.00 16.41  ? 509 TRP A CB  1 
ATOM   3362  C CG  . TRP A 1 509 ? 117.649 109.922 154.949 1.00 17.24  ? 509 TRP A CG  1 
ATOM   3363  C CD1 . TRP A 1 509 ? 117.747 109.361 156.171 1.00 16.52  ? 509 TRP A CD1 1 
ATOM   3364  C CD2 . TRP A 1 509 ? 116.220 110.118 154.720 1.00 26.27  ? 509 TRP A CD2 1 
ATOM   3365  N NE1 . TRP A 1 509 ? 116.483 109.155 156.680 1.00 17.42  ? 509 TRP A NE1 1 
ATOM   3366  C CE2 . TRP A 1 509 ? 115.504 109.559 155.813 1.00 23.38  ? 509 TRP A CE2 1 
ATOM   3367  C CE3 . TRP A 1 509 ? 115.450 110.698 153.687 1.00 28.04  ? 509 TRP A CE3 1 
ATOM   3368  C CZ2 . TRP A 1 509 ? 114.103 109.506 155.852 1.00 18.55  ? 509 TRP A CZ2 1 
ATOM   3369  C CZ3 . TRP A 1 509 ? 114.043 110.659 153.722 1.00 28.77  ? 509 TRP A CZ3 1 
ATOM   3370  C CH2 . TRP A 1 509 ? 113.368 110.038 154.785 1.00 24.48  ? 509 TRP A CH2 1 
ATOM   3371  N N   . LEU A 1 510 ? 120.753 109.609 151.453 1.00 16.98  ? 510 LEU A N   1 
ATOM   3372  C CA  . LEU A 1 510 ? 121.489 109.949 150.242 1.00 15.45  ? 510 LEU A CA  1 
ATOM   3373  C C   . LEU A 1 510 ? 121.055 109.074 149.060 1.00 17.71  ? 510 LEU A C   1 
ATOM   3374  O O   . LEU A 1 510 ? 120.928 109.571 147.948 1.00 31.40  ? 510 LEU A O   1 
ATOM   3375  C CB  . LEU A 1 510 ? 122.996 109.846 150.515 1.00 25.60  ? 510 LEU A CB  1 
ATOM   3376  C CG  . LEU A 1 510 ? 123.526 110.803 151.596 1.00 21.98  ? 510 LEU A CG  1 
ATOM   3377  C CD1 . LEU A 1 510 ? 125.004 110.550 151.834 1.00 17.29  ? 510 LEU A CD1 1 
ATOM   3378  C CD2 . LEU A 1 510 ? 123.329 112.259 151.219 1.00 22.35  ? 510 LEU A CD2 1 
ATOM   3379  N N   . ASN A 1 511 ? 120.737 107.804 149.296 1.00 16.52  ? 511 ASN A N   1 
ATOM   3380  C CA  . ASN A 1 511 ? 120.181 106.898 148.297 1.00 4.47   ? 511 ASN A CA  1 
ATOM   3381  C C   . ASN A 1 511 ? 118.820 107.327 147.744 1.00 4.09   ? 511 ASN A C   1 
ATOM   3382  O O   . ASN A 1 511 ? 118.559 107.066 146.576 1.00 29.61  ? 511 ASN A O   1 
ATOM   3383  C CB  . ASN A 1 511 ? 120.115 105.486 148.874 1.00 9.82   ? 511 ASN A CB  1 
ATOM   3384  C CG  . ASN A 1 511 ? 121.445 104.770 148.899 1.00 11.41  ? 511 ASN A CG  1 
ATOM   3385  O OD1 . ASN A 1 511 ? 122.434 105.206 148.341 1.00 21.80  ? 511 ASN A OD1 1 
ATOM   3386  N ND2 . ASN A 1 511 ? 121.503 103.616 149.508 1.00 8.75   ? 511 ASN A ND2 1 
ATOM   3387  N N   . LEU A 1 512 ? 117.969 108.037 148.488 1.00 14.32  ? 512 LEU A N   1 
ATOM   3388  C CA  . LEU A 1 512 ? 116.710 108.565 147.940 1.00 7.02   ? 512 LEU A CA  1 
ATOM   3389  C C   . LEU A 1 512 ? 116.916 109.559 146.792 1.00 13.89  ? 512 LEU A C   1 
ATOM   3390  O O   . LEU A 1 512 ? 116.016 109.734 145.978 1.00 19.91  ? 512 LEU A O   1 
ATOM   3391  C CB  . LEU A 1 512 ? 115.851 109.196 149.047 1.00 15.26  ? 512 LEU A CB  1 
ATOM   3392  C CG  . LEU A 1 512 ? 115.083 108.149 149.860 1.00 21.07  ? 512 LEU A CG  1 
ATOM   3393  C CD1 . LEU A 1 512 ? 114.769 108.672 151.246 1.00 32.24  ? 512 LEU A CD1 1 
ATOM   3394  C CD2 . LEU A 1 512 ? 113.756 107.796 149.198 1.00 15.70  ? 512 LEU A CD2 1 
ATOM   3395  N N   . LEU A 1 513 ? 118.096 110.164 146.657 1.00 13.74  ? 513 LEU A N   1 
ATOM   3396  C CA  . LEU A 1 513 ? 118.413 111.038 145.534 1.00 14.71  ? 513 LEU A CA  1 
ATOM   3397  C C   . LEU A 1 513 ? 118.489 110.308 144.189 1.00 14.48  ? 513 LEU A C   1 
ATOM   3398  O O   . LEU A 1 513 ? 118.367 110.966 143.161 1.00 28.09  ? 513 LEU A O   1 
ATOM   3399  C CB  . LEU A 1 513 ? 119.696 111.824 145.815 1.00 25.49  ? 513 LEU A CB  1 
ATOM   3400  C CG  . LEU A 1 513 ? 119.579 112.767 147.023 1.00 21.25  ? 513 LEU A CG  1 
ATOM   3401  C CD1 . LEU A 1 513 ? 120.963 113.280 147.385 1.00 19.06  ? 513 LEU A CD1 1 
ATOM   3402  C CD2 . LEU A 1 513 ? 118.665 113.954 146.726 1.00 12.81  ? 513 LEU A CD2 1 
ATOM   3403  N N   . TYR A 1 514 ? 118.588 108.976 144.175 1.00 14.47  ? 514 TYR A N   1 
ATOM   3404  C CA  . TYR A 1 514 ? 118.434 108.161 142.975 1.00 5.89   ? 514 TYR A CA  1 
ATOM   3405  C C   . TYR A 1 514 ? 117.111 108.447 142.252 1.00 11.67  ? 514 TYR A C   1 
ATOM   3406  O O   . TYR A 1 514 ? 117.089 108.674 141.047 1.00 30.46  ? 514 TYR A O   1 
ATOM   3407  C CB  . TYR A 1 514 ? 118.520 106.685 143.373 1.00 12.68  ? 514 TYR A CB  1 
ATOM   3408  C CG  . TYR A 1 514 ? 118.177 105.728 142.258 1.00 16.49  ? 514 TYR A CG  1 
ATOM   3409  C CD1 . TYR A 1 514 ? 119.129 105.406 141.278 1.00 12.12  ? 514 TYR A CD1 1 
ATOM   3410  C CD2 . TYR A 1 514 ? 116.870 105.222 142.162 1.00 15.27  ? 514 TYR A CD2 1 
ATOM   3411  C CE1 . TYR A 1 514 ? 118.762 104.589 140.194 1.00 11.45  ? 514 TYR A CE1 1 
ATOM   3412  C CE2 . TYR A 1 514 ? 116.492 104.426 141.074 1.00 6.72   ? 514 TYR A CE2 1 
ATOM   3413  C CZ  . TYR A 1 514 ? 117.441 104.116 140.081 1.00 11.98  ? 514 TYR A CZ  1 
ATOM   3414  O OH  . TYR A 1 514 ? 117.094 103.351 139.020 1.00 30.84  ? 514 TYR A OH  1 
ATOM   3415  N N   . TYR A 1 515 ? 116.002 108.493 142.990 1.00 21.80  ? 515 TYR A N   1 
ATOM   3416  C CA  . TYR A 1 515 ? 114.657 108.612 142.434 1.00 13.81  ? 515 TYR A CA  1 
ATOM   3417  C C   . TYR A 1 515 ? 114.333 109.996 141.874 1.00 9.76   ? 515 TYR A C   1 
ATOM   3418  O O   . TYR A 1 515 ? 113.310 110.176 141.227 1.00 21.92  ? 515 TYR A O   1 
ATOM   3419  C CB  . TYR A 1 515 ? 113.623 108.148 143.459 1.00 12.60  ? 515 TYR A CB  1 
ATOM   3420  C CG  . TYR A 1 515 ? 113.842 106.733 143.939 1.00 17.10  ? 515 TYR A CG  1 
ATOM   3421  C CD1 . TYR A 1 515 ? 113.359 105.638 143.198 1.00 15.80  ? 515 TYR A CD1 1 
ATOM   3422  C CD2 . TYR A 1 515 ? 114.551 106.516 145.132 1.00 7.40   ? 515 TYR A CD2 1 
ATOM   3423  C CE1 . TYR A 1 515 ? 113.578 104.325 143.653 1.00 11.60  ? 515 TYR A CE1 1 
ATOM   3424  C CE2 . TYR A 1 515 ? 114.767 105.211 145.589 1.00 13.61  ? 515 TYR A CE2 1 
ATOM   3425  C CZ  . TYR A 1 515 ? 114.285 104.114 144.852 1.00 15.97  ? 515 TYR A CZ  1 
ATOM   3426  O OH  . TYR A 1 515 ? 114.526 102.868 145.315 1.00 20.50  ? 515 TYR A OH  1 
ATOM   3427  N N   . THR A 1 516 ? 115.238 110.967 142.001 1.00 10.98  ? 516 THR A N   1 
ATOM   3428  C CA  . THR A 1 516 ? 115.095 112.268 141.336 1.00 17.12  ? 516 THR A CA  1 
ATOM   3429  C C   . THR A 1 516 ? 115.038 112.152 139.813 1.00 21.82  ? 516 THR A C   1 
ATOM   3430  O O   . THR A 1 516 ? 114.439 113.020 139.187 1.00 37.61  ? 516 THR A O   1 
ATOM   3431  C CB  . THR A 1 516 ? 116.194 113.259 141.732 1.00 22.25  ? 516 THR A CB  1 
ATOM   3432  O OG1 . THR A 1 516 ? 117.466 112.805 141.359 1.00 31.57  ? 516 THR A OG1 1 
ATOM   3433  C CG2 . THR A 1 516 ? 116.189 113.602 143.212 1.00 11.50  ? 516 THR A CG2 1 
ATOM   3434  N N   . ARG A 1 517 ? 115.561 111.076 139.208 1.00 17.60  ? 517 ARG A N   1 
ATOM   3435  C CA  . ARG A 1 517 ? 115.456 110.765 137.768 1.00 9.33   ? 517 ARG A CA  1 
ATOM   3436  C C   . ARG A 1 517 ? 114.046 110.443 137.261 1.00 18.53  ? 517 ARG A C   1 
ATOM   3437  O O   . ARG A 1 517 ? 113.839 110.438 136.051 1.00 32.44  ? 517 ARG A O   1 
ATOM   3438  C CB  . ARG A 1 517 ? 116.456 109.659 137.407 1.00 17.52  ? 517 ARG A CB  1 
ATOM   3439  C CG  . ARG A 1 517 ? 116.048 108.264 137.907 1.00 19.87  ? 517 ARG A CG  1 
ATOM   3440  C CD  . ARG A 1 517 ? 117.163 107.232 137.802 1.00 5.49   ? 517 ARG A CD  1 
ATOM   3441  N NE  . ARG A 1 517 ? 118.345 107.668 138.560 1.00 19.08  ? 517 ARG A NE  1 
ATOM   3442  C CZ  . ARG A 1 517 ? 119.602 107.434 138.266 1.00 17.22  ? 517 ARG A CZ  1 
ATOM   3443  N NH1 . ARG A 1 517 ? 120.548 108.103 138.838 1.00 12.05  ? 517 ARG A NH1 1 
ATOM   3444  N NH2 . ARG A 1 517 ? 119.943 106.540 137.390 1.00 24.62  ? 517 ARG A NH2 1 
ATOM   3445  N N   . GLY A 1 518 ? 113.074 110.206 138.141 1.00 27.90  ? 518 GLY A N   1 
ATOM   3446  C CA  . GLY A 1 518 ? 111.690 109.920 137.766 1.00 21.23  ? 518 GLY A CA  1 
ATOM   3447  C C   . GLY A 1 518 ? 110.936 111.103 137.158 1.00 21.86  ? 518 GLY A C   1 
ATOM   3448  O O   . GLY A 1 518 ? 109.989 110.896 136.405 1.00 39.14  ? 518 GLY A O   1 
ATOM   3449  N N   . PHE A 1 519 ? 111.366 112.332 137.432 1.00 10.80  ? 519 PHE A N   1 
ATOM   3450  C CA  . PHE A 1 519 ? 110.775 113.555 136.894 1.00 21.77  ? 519 PHE A CA  1 
ATOM   3451  C C   . PHE A 1 519 ? 111.787 114.301 136.042 1.00 28.02  ? 519 PHE A C   1 
ATOM   3452  O O   . PHE A 1 519 ? 112.960 114.362 136.395 1.00 31.45  ? 519 PHE A O   1 
ATOM   3453  C CB  . PHE A 1 519 ? 110.287 114.471 138.021 1.00 25.26  ? 519 PHE A CB  1 
ATOM   3454  C CG  . PHE A 1 519 ? 109.318 113.833 138.988 1.00 24.89  ? 519 PHE A CG  1 
ATOM   3455  C CD1 . PHE A 1 519 ? 107.991 113.596 138.594 1.00 23.56  ? 519 PHE A CD1 1 
ATOM   3456  C CD2 . PHE A 1 519 ? 109.742 113.485 140.279 1.00 25.48  ? 519 PHE A CD2 1 
ATOM   3457  C CE1 . PHE A 1 519 ? 107.086 113.014 139.494 1.00 27.79  ? 519 PHE A CE1 1 
ATOM   3458  C CE2 . PHE A 1 519 ? 108.834 112.915 141.182 1.00 32.69  ? 519 PHE A CE2 1 
ATOM   3459  C CZ  . PHE A 1 519 ? 107.506 112.681 140.790 1.00 29.14  ? 519 PHE A CZ  1 
ATOM   3460  N N   . GLN A 1 520 ? 111.348 114.919 134.953 1.00 40.23  ? 520 GLN A N   1 
ATOM   3461  C CA  . GLN A 1 520 ? 112.237 115.676 134.073 1.00 34.08  ? 520 GLN A CA  1 
ATOM   3462  C C   . GLN A 1 520 ? 112.919 116.837 134.794 1.00 35.19  ? 520 GLN A C   1 
ATOM   3463  O O   . GLN A 1 520 ? 114.118 117.038 134.647 1.00 35.74  ? 520 GLN A O   1 
ATOM   3464  C CB  . GLN A 1 520 ? 111.428 116.144 132.858 1.00 33.61  ? 520 GLN A CB  1 
ATOM   3465  C CG  . GLN A 1 520 ? 112.313 116.824 131.810 1.00 35.52  ? 520 GLN A CG  1 
ATOM   3466  C CD  . GLN A 1 520 ? 111.639 117.002 130.452 1.00 39.99  ? 520 GLN A CD  1 
ATOM   3467  O OE1 . GLN A 1 520 ? 110.770 116.252 130.035 1.00 43.46  ? 520 GLN A OE1 1 
ATOM   3468  N NE2 . GLN A 1 520 ? 112.023 118.002 129.700 1.00 43.24  ? 520 GLN A NE2 1 
ATOM   3469  N N   . HIS A 1 521 ? 112.174 117.572 135.621 1.00 38.54  ? 521 HIS A N   1 
ATOM   3470  C CA  . HIS A 1 521 ? 112.654 118.779 136.292 1.00 36.47  ? 521 HIS A CA  1 
ATOM   3471  C C   . HIS A 1 521 ? 113.793 118.491 137.276 1.00 35.33  ? 521 HIS A C   1 
ATOM   3472  O O   . HIS A 1 521 ? 114.867 119.094 137.106 1.00 37.80  ? 521 HIS A O   1 
ATOM   3473  C CB  . HIS A 1 521 ? 111.505 119.505 137.007 1.00 36.51  ? 521 HIS A CB  1 
ATOM   3474  C CG  . HIS A 1 521 ? 111.865 120.893 137.418 1.00 42.93  ? 521 HIS A CG  1 
ATOM   3475  N ND1 . HIS A 1 521 ? 111.545 121.406 138.661 1.00 45.28  ? 521 HIS A ND1 1 
ATOM   3476  C CD2 . HIS A 1 521 ? 112.526 121.873 136.764 1.00 37.78  ? 521 HIS A CD2 1 
ATOM   3477  C CE1 . HIS A 1 521 ? 111.986 122.645 138.750 1.00 44.11  ? 521 HIS A CE1 1 
ATOM   3478  N NE2 . HIS A 1 521 ? 112.593 122.955 137.599 1.00 44.67  ? 521 HIS A NE2 1 
ATOM   3479  N N   . THR A 1 522 ? 113.603 117.568 138.222 1.00 34.79  ? 522 THR A N   1 
ATOM   3480  C CA  . THR A 1 522 ? 114.682 117.189 139.173 1.00 32.05  ? 522 THR A CA  1 
ATOM   3481  C C   . THR A 1 522 ? 115.720 116.323 138.451 1.00 32.05  ? 522 THR A C   1 
ATOM   3482  O O   . THR A 1 522 ? 116.925 116.595 138.616 1.00 25.81  ? 522 THR A O   1 
ATOM   3483  C CB  . THR A 1 522 ? 114.106 116.464 140.396 1.00 33.41  ? 522 THR A CB  1 
ATOM   3484  O OG1 . THR A 1 522 ? 113.449 115.282 139.938 1.00 32.17  ? 522 THR A OG1 1 
ATOM   3485  C CG2 . THR A 1 522 ? 113.133 117.318 141.179 1.00 26.45  ? 522 THR A CG2 1 
ATOM   3486  N N   . GLY A 1 523 ? 115.264 115.326 137.685 1.00 36.86  ? 523 GLY A N   1 
ATOM   3487  C CA  . GLY A 1 523 ? 116.186 114.431 136.959 1.00 24.07  ? 523 GLY A CA  1 
ATOM   3488  C C   . GLY A 1 523 ? 117.277 115.204 136.241 1.00 31.16  ? 523 GLY A C   1 
ATOM   3489  O O   . GLY A 1 523 ? 118.455 115.051 136.621 1.00 49.85  ? 523 GLY A O   1 
ATOM   3490  N N   . ILE A 1 524 ? 116.903 116.007 135.241 1.00 29.92  ? 524 ILE A N   1 
ATOM   3491  C CA  . ILE A 1 524 ? 117.887 116.783 134.478 1.00 31.74  ? 524 ILE A CA  1 
ATOM   3492  C C   . ILE A 1 524 ? 118.770 117.621 135.415 1.00 41.79  ? 524 ILE A C   1 
ATOM   3493  O O   . ILE A 1 524 ? 119.974 117.723 135.179 1.00 42.74  ? 524 ILE A O   1 
ATOM   3494  C CB  . ILE A 1 524 ? 117.163 117.626 133.408 1.00 41.04  ? 524 ILE A CB  1 
ATOM   3495  C CG1 . ILE A 1 524 ? 116.560 116.675 132.353 1.00 34.90  ? 524 ILE A CG1 1 
ATOM   3496  C CG2 . ILE A 1 524 ? 118.098 118.637 132.734 1.00 35.45  ? 524 ILE A CG2 1 
ATOM   3497  C CD1 . ILE A 1 524 ? 115.783 117.373 131.244 1.00 31.89  ? 524 ILE A CD1 1 
ATOM   3498  N N   . TYR A 1 525 ? 118.240 118.173 136.511 1.00 37.19  ? 525 TYR A N   1 
ATOM   3499  C CA  . TYR A 1 525 ? 119.072 118.924 137.455 1.00 33.71  ? 525 TYR A CA  1 
ATOM   3500  C C   . TYR A 1 525 ? 120.095 118.049 138.177 1.00 37.89  ? 525 TYR A C   1 
ATOM   3501  O O   . TYR A 1 525 ? 121.258 118.427 138.296 1.00 44.93  ? 525 TYR A O   1 
ATOM   3502  C CB  . TYR A 1 525 ? 118.214 119.682 138.458 1.00 40.27  ? 525 TYR A CB  1 
ATOM   3503  C CG  . TYR A 1 525 ? 119.008 120.728 139.208 1.00 34.78  ? 525 TYR A CG  1 
ATOM   3504  C CD1 . TYR A 1 525 ? 119.473 121.856 138.511 1.00 31.38  ? 525 TYR A CD1 1 
ATOM   3505  C CD2 . TYR A 1 525 ? 119.349 120.544 140.561 1.00 32.65  ? 525 TYR A CD2 1 
ATOM   3506  C CE1 . TYR A 1 525 ? 120.262 122.816 139.161 1.00 43.21  ? 525 TYR A CE1 1 
ATOM   3507  C CE2 . TYR A 1 525 ? 120.144 121.504 141.213 1.00 41.04  ? 525 TYR A CE2 1 
ATOM   3508  C CZ  . TYR A 1 525 ? 120.601 122.644 140.518 1.00 43.96  ? 525 TYR A CZ  1 
ATOM   3509  O OH  . TYR A 1 525 ? 121.391 123.554 141.141 1.00 32.72  ? 525 TYR A OH  1 
ATOM   3510  N N   . SER A 1 526 ? 119.715 116.841 138.577 1.00 26.86  ? 526 SER A N   1 
ATOM   3511  C CA  . SER A 1 526 ? 120.652 115.848 139.096 1.00 34.60  ? 526 SER A CA  1 
ATOM   3512  C C   . SER A 1 526 ? 121.816 115.558 138.134 1.00 39.72  ? 526 SER A C   1 
ATOM   3513  O O   . SER A 1 526 ? 122.936 115.353 138.589 1.00 48.34  ? 526 SER A O   1 
ATOM   3514  C CB  . SER A 1 526 ? 119.872 114.585 139.441 1.00 40.06  ? 526 SER A CB  1 
ATOM   3515  O OG  . SER A 1 526 ? 119.196 114.787 140.661 1.00 46.67  ? 526 SER A OG  1 
ATOM   3516  N N   . VAL A 1 527 ? 121.605 115.666 136.820 1.00 39.54  ? 527 VAL A N   1 
ATOM   3517  C CA  . VAL A 1 527 ? 122.659 115.586 135.799 1.00 40.11  ? 527 VAL A CA  1 
ATOM   3518  C C   . VAL A 1 527 ? 123.484 116.876 135.667 1.00 40.47  ? 527 VAL A C   1 
ATOM   3519  O O   . VAL A 1 527 ? 124.707 116.813 135.607 1.00 42.00  ? 527 VAL A O   1 
ATOM   3520  C CB  . VAL A 1 527 ? 122.048 115.193 134.445 1.00 40.79  ? 527 VAL A CB  1 
ATOM   3521  C CG1 . VAL A 1 527 ? 123.087 115.221 133.336 1.00 42.41  ? 527 VAL A CG1 1 
ATOM   3522  C CG2 . VAL A 1 527 ? 121.465 113.783 134.483 1.00 35.77  ? 527 VAL A CG2 1 
ATOM   3523  N N   . MET A 1 528 ? 122.856 118.055 135.667 1.00 47.86  ? 528 MET A N   1 
ATOM   3524  C CA  . MET A 1 528 ? 123.558 119.352 135.678 1.00 47.15  ? 528 MET A CA  1 
ATOM   3525  C C   . MET A 1 528 ? 124.501 119.492 136.888 1.00 48.01  ? 528 MET A C   1 
ATOM   3526  O O   . MET A 1 528 ? 125.612 119.997 136.770 1.00 49.95  ? 528 MET A O   1 
ATOM   3527  C CB  . MET A 1 528 ? 122.531 120.493 135.703 1.00 47.41  ? 528 MET A CB  1 
ATOM   3528  C CG  . MET A 1 528 ? 121.699 120.587 134.423 1.00 49.07  ? 528 MET A CG  1 
ATOM   3529  S SD  . MET A 1 528 ? 120.239 121.646 134.613 1.00 66.06  ? 528 MET A SD  1 
ATOM   3530  C CE  . MET A 1 528 ? 119.944 122.048 132.873 1.00 50.00  ? 528 MET A CE  1 
ATOM   3531  N N   . ILE A 1 529 ? 124.087 118.977 138.043 1.00 51.56  ? 529 ILE A N   1 
ATOM   3532  C CA  . ILE A 1 529 ? 124.878 118.990 139.319 1.00 51.31  ? 529 ILE A CA  1 
ATOM   3533  C C   . ILE A 1 529 ? 126.046 117.986 139.316 1.00 51.87  ? 529 ILE A C   1 
ATOM   3534  O O   . ILE A 1 529 ? 126.794 117.968 140.284 1.00 60.31  ? 529 ILE A O   1 
ATOM   3535  C CB  . ILE A 1 529 ? 123.947 118.754 140.525 1.00 52.74  ? 529 ILE A CB  1 
ATOM   3536  C CG1 . ILE A 1 529 ? 123.014 119.945 140.752 1.00 54.40  ? 529 ILE A CG1 1 
ATOM   3537  C CG2 . ILE A 1 529 ? 124.753 118.426 141.773 1.00 53.01  ? 529 ILE A CG2 1 
ATOM   3538  C CD1 . ILE A 1 529 ? 123.739 121.253 140.966 1.00 46.50  ? 529 ILE A CD1 1 
ATOM   3539  N N   . GLN A 1 530 ? 126.321 117.226 138.253 1.00 47.24  ? 530 GLN A N   1 
ATOM   3540  C CA  . GLN A 1 530 ? 127.549 116.416 138.146 1.00 41.59  ? 530 GLN A CA  1 
ATOM   3541  C C   . GLN A 1 530 ? 128.785 117.193 137.641 1.00 45.96  ? 530 GLN A C   1 
ATOM   3542  O O   . GLN A 1 530 ? 129.867 116.615 137.620 1.00 48.08  ? 530 GLN A O   1 
ATOM   3543  C CB  . GLN A 1 530 ? 127.317 115.200 137.236 1.00 51.71  ? 530 GLN A CB  1 
ATOM   3544  C CG  . GLN A 1 530 ? 126.100 114.337 137.580 1.00 53.26  ? 530 GLN A CG  1 
ATOM   3545  C CD  . GLN A 1 530 ? 126.137 113.753 138.981 1.00 50.21  ? 530 GLN A CD  1 
ATOM   3546  O OE1 . GLN A 1 530 ? 127.054 113.051 139.373 1.00 57.01  ? 530 GLN A OE1 1 
ATOM   3547  N NE2 . GLN A 1 530 ? 125.106 113.965 139.759 1.00 48.20  ? 530 GLN A NE2 1 
ATOM   3548  N N   . LYS A 1 531 ? 128.663 118.457 137.203 1.00 47.06  ? 531 LYS A N   1 
ATOM   3549  C CA  . LYS A 1 531 ? 129.708 119.260 136.519 1.00 46.17  ? 531 LYS A CA  1 
ATOM   3550  C C   . LYS A 1 531 ? 131.130 119.051 137.048 1.00 49.37  ? 531 LYS A C   1 
ATOM   3551  O O   . LYS A 1 531 ? 132.040 118.731 136.289 1.00 51.03  ? 531 LYS A O   1 
ATOM   3552  C CB  . LYS A 1 531 ? 129.354 120.766 136.633 1.00 46.33  ? 531 LYS A CB  1 
ATOM   3553  C CG  . LYS A 1 531 ? 128.468 121.312 135.507 1.00 46.96  ? 531 LYS A CG  1 
ATOM   3554  C CD  . LYS A 1 531 ? 129.258 121.582 134.222 1.00 48.94  ? 531 LYS A CD  1 
ATOM   3555  C CE  . LYS A 1 531 ? 128.364 122.255 133.174 1.00 52.22  ? 531 LYS A CE  1 
ATOM   3556  N NZ  . LYS A 1 531 ? 129.102 122.564 131.918 1.00 52.14  ? 531 LYS A NZ  1 
ATOM   3557  N N   . VAL A 1 532 ? 131.326 119.276 138.342 1.00 54.32  ? 532 VAL A N   1 
ATOM   3558  C CA  . VAL A 1 532 ? 132.596 119.170 139.066 1.00 49.39  ? 532 VAL A CA  1 
ATOM   3559  C C   . VAL A 1 532 ? 132.756 117.733 139.554 1.00 54.18  ? 532 VAL A C   1 
ATOM   3560  O O   . VAL A 1 532 ? 132.277 117.341 140.620 1.00 57.59  ? 532 VAL A O   1 
ATOM   3561  C CB  . VAL A 1 532 ? 132.655 120.200 140.209 1.00 50.48  ? 532 VAL A CB  1 
ATOM   3562  C CG1 . VAL A 1 532 ? 133.974 120.107 140.971 1.00 51.39  ? 532 VAL A CG1 1 
ATOM   3563  C CG2 . VAL A 1 532 ? 132.506 121.624 139.656 1.00 49.75  ? 532 VAL A CG2 1 
ATOM   3564  N N   . ILE A 1 533 ? 133.406 116.920 138.724 1.00 59.56  ? 533 ILE A N   1 
ATOM   3565  C CA  . ILE A 1 533 ? 133.717 115.518 139.013 1.00 58.40  ? 533 ILE A CA  1 
ATOM   3566  C C   . ILE A 1 533 ? 134.726 115.460 140.175 1.00 51.11  ? 533 ILE A C   1 
ATOM   3567  O O   . ILE A 1 533 ? 135.493 116.398 140.399 1.00 49.52  ? 533 ILE A O   1 
ATOM   3568  C CB  . ILE A 1 533 ? 134.245 114.825 137.721 1.00 53.51  ? 533 ILE A CB  1 
ATOM   3569  C CG1 . ILE A 1 533 ? 133.346 115.055 136.482 1.00 50.59  ? 533 ILE A CG1 1 
ATOM   3570  C CG2 . ILE A 1 533 ? 134.444 113.306 137.875 1.00 52.75  ? 533 ILE A CG2 1 
ATOM   3571  C CD1 . ILE A 1 533 ? 131.964 114.403 136.555 1.00 48.41  ? 533 ILE A CD1 1 
ATOM   3572  N N   . LEU A 1 534 ? 134.831 114.325 140.864 1.00 46.49  ? 534 LEU A N   1 
ATOM   3573  C CA  . LEU A 1 534 ? 135.971 114.059 141.750 1.00 47.81  ? 534 LEU A CA  1 
ATOM   3574  C C   . LEU A 1 534 ? 137.331 114.115 141.032 1.00 49.02  ? 534 LEU A C   1 
ATOM   3575  O O   . LEU A 1 534 ? 138.347 114.184 141.702 1.00 55.50  ? 534 LEU A O   1 
ATOM   3576  C CB  . LEU A 1 534 ? 135.797 112.702 142.455 1.00 52.10  ? 534 LEU A CB  1 
ATOM   3577  C CG  . LEU A 1 534 ? 134.568 112.596 143.371 1.00 54.72  ? 534 LEU A CG  1 
ATOM   3578  C CD1 . LEU A 1 534 ? 134.500 111.182 143.941 1.00 53.65  ? 534 LEU A CD1 1 
ATOM   3579  C CD2 . LEU A 1 534 ? 134.624 113.592 144.527 1.00 52.05  ? 534 LEU A CD2 1 
ATOM   3580  N N   . ARG A 1 535 ? 137.338 114.145 139.694 1.00 47.02  ? 535 ARG A N   1 
ATOM   3581  C CA  . ARG A 1 535 ? 138.597 114.188 138.887 1.00 47.10  ? 535 ARG A CA  1 
ATOM   3582  C C   . ARG A 1 535 ? 139.506 115.326 139.365 1.00 47.08  ? 535 ARG A C   1 
ATOM   3583  O O   . ARG A 1 535 ? 140.705 115.063 139.584 1.00 48.92  ? 535 ARG A O   1 
ATOM   3584  C CB  . ARG A 1 535 ? 138.195 114.331 137.411 1.00 49.32  ? 535 ARG A CB  1 
ATOM   3585  C CG  . ARG A 1 535 ? 139.366 114.136 136.437 1.00 47.93  ? 535 ARG A CG  1 
ATOM   3586  C CD  . ARG A 1 535 ? 139.078 114.800 135.092 1.00 47.60  ? 535 ARG A CD  1 
ATOM   3587  N NE  . ARG A 1 535 ? 139.005 116.247 135.243 1.00 50.84  ? 535 ARG A NE  1 
ATOM   3588  C CZ  . ARG A 1 535 ? 138.827 117.106 134.246 1.00 51.33  ? 535 ARG A CZ  1 
ATOM   3589  N NH1 . ARG A 1 535 ? 138.777 118.403 134.494 1.00 45.90  ? 535 ARG A NH1 1 
ATOM   3590  N NH2 . ARG A 1 535 ? 138.702 116.665 133.007 1.00 49.27  ? 535 ARG A NH2 1 
ATOM   3591  N N   . ASP A 1 536 ? 138.960 116.535 139.517 1.00 41.47  ? 536 ASP A N   1 
ATOM   3592  C CA  . ASP A 1 536 ? 139.760 117.694 139.926 1.00 37.39  ? 536 ASP A CA  1 
ATOM   3593  C C   . ASP A 1 536 ? 139.818 117.854 141.440 1.00 40.90  ? 536 ASP A C   1 
ATOM   3594  O O   . ASP A 1 536 ? 140.888 118.095 141.982 1.00 46.81  ? 536 ASP A O   1 
ATOM   3595  C CB  . ASP A 1 536 ? 139.303 118.967 139.212 1.00 40.80  ? 536 ASP A CB  1 
ATOM   3596  C CG  . ASP A 1 536 ? 139.604 118.936 137.707 1.00 46.75  ? 536 ASP A CG  1 
ATOM   3597  O OD1 . ASP A 1 536 ? 140.154 117.927 137.214 1.00 46.54  ? 536 ASP A OD1 1 
ATOM   3598  O OD2 . ASP A 1 536 ? 139.286 119.900 136.989 1.00 47.40  ? 536 ASP A OD2 1 
ATOM   3599  N N   . LEU A 1 537 ? 138.720 117.643 142.162 1.00 39.50  ? 537 LEU A N   1 
ATOM   3600  C CA  . LEU A 1 537 ? 138.727 117.772 143.617 1.00 33.77  ? 537 LEU A CA  1 
ATOM   3601  C C   . LEU A 1 537 ? 139.582 116.714 144.322 1.00 40.21  ? 537 LEU A C   1 
ATOM   3602  O O   . LEU A 1 537 ? 140.212 117.049 145.314 1.00 49.38  ? 537 LEU A O   1 
ATOM   3603  C CB  . LEU A 1 537 ? 137.289 117.838 144.153 1.00 36.89  ? 537 LEU A CB  1 
ATOM   3604  C CG  . LEU A 1 537 ? 136.884 119.289 144.430 1.00 41.91  ? 537 LEU A CG  1 
ATOM   3605  C CD1 . LEU A 1 537 ? 136.929 120.176 143.192 1.00 41.74  ? 537 LEU A CD1 1 
ATOM   3606  C CD2 . LEU A 1 537 ? 135.479 119.325 145.000 1.00 44.21  ? 537 LEU A CD2 1 
ATOM   3607  N N   . LEU A 1 538 ? 139.707 115.487 143.809 1.00 40.83  ? 538 LEU A N   1 
ATOM   3608  C CA  . LEU A 1 538 ? 140.638 114.490 144.347 1.00 43.94  ? 538 LEU A CA  1 
ATOM   3609  C C   . LEU A 1 538 ? 142.111 114.847 144.076 1.00 40.94  ? 538 LEU A C   1 
ATOM   3610  O O   . LEU A 1 538 ? 142.992 114.486 144.851 1.00 45.46  ? 538 LEU A O   1 
ATOM   3611  C CB  . LEU A 1 538 ? 140.263 113.107 143.775 1.00 44.76  ? 538 LEU A CB  1 
ATOM   3612  C CG  . LEU A 1 538 ? 141.045 111.906 144.319 1.00 46.80  ? 538 LEU A CG  1 
ATOM   3613  C CD1 . LEU A 1 538 ? 140.909 111.746 145.823 1.00 43.12  ? 538 LEU A CD1 1 
ATOM   3614  C CD2 . LEU A 1 538 ? 140.526 110.636 143.664 1.00 43.33  ? 538 LEU A CD2 1 
ATOM   3615  N N   . ARG A 1 539 ? 142.352 115.625 143.007 1.00 32.43  ? 539 ARG A N   1 
ATOM   3616  C CA  . ARG A 1 539 ? 143.737 116.090 142.679 1.00 30.20  ? 539 ARG A CA  1 
ATOM   3617  C C   . ARG A 1 539 ? 144.054 117.292 143.579 1.00 34.69  ? 539 ARG A C   1 
ATOM   3618  O O   . ARG A 1 539 ? 145.131 117.280 144.207 1.00 46.82  ? 539 ARG A O   1 
ATOM   3619  C CB  . ARG A 1 539 ? 143.871 116.253 141.162 1.00 41.51  ? 539 ARG A CB  1 
ATOM   3620  C CG  . ARG A 1 539 ? 143.793 114.912 140.426 1.00 42.33  ? 539 ARG A CG  1 
ATOM   3621  C CD  . ARG A 1 539 ? 144.186 115.056 138.956 1.00 38.32  ? 539 ARG A CD  1 
ATOM   3622  N NE  . ARG A 1 539 ? 143.267 115.923 138.233 1.00 40.36  ? 539 ARG A NE  1 
ATOM   3623  C CZ  . ARG A 1 539 ? 143.341 116.183 136.932 1.00 41.43  ? 539 ARG A CZ  1 
ATOM   3624  N NH1 . ARG A 1 539 ? 142.457 116.986 136.366 1.00 39.17  ? 539 ARG A NH1 1 
ATOM   3625  N NH2 . ARG A 1 539 ? 144.297 115.637 136.202 1.00 36.79  ? 539 ARG A NH2 1 
ATOM   3626  N N   . PHE A 1 540 ? 143.159 118.277 143.652 1.00 36.16  ? 540 PHE A N   1 
ATOM   3627  C CA  . PHE A 1 540 ? 143.289 119.402 144.584 1.00 31.41  ? 540 PHE A CA  1 
ATOM   3628  C C   . PHE A 1 540 ? 143.478 118.909 146.020 1.00 25.90  ? 540 PHE A C   1 
ATOM   3629  O O   . PHE A 1 540 ? 144.319 119.440 146.741 1.00 28.93  ? 540 PHE A O   1 
ATOM   3630  C CB  . PHE A 1 540 ? 142.059 120.315 144.454 1.00 31.28  ? 540 PHE A CB  1 
ATOM   3631  C CG  . PHE A 1 540 ? 141.652 121.027 145.729 1.00 38.71  ? 540 PHE A CG  1 
ATOM   3632  C CD1 . PHE A 1 540 ? 142.297 122.213 146.133 1.00 36.41  ? 540 PHE A CD1 1 
ATOM   3633  C CD2 . PHE A 1 540 ? 140.652 120.467 146.547 1.00 35.25  ? 540 PHE A CD2 1 
ATOM   3634  C CE1 . PHE A 1 540 ? 141.953 122.818 147.350 1.00 27.55  ? 540 PHE A CE1 1 
ATOM   3635  C CE2 . PHE A 1 540 ? 140.331 121.055 147.776 1.00 32.86  ? 540 PHE A CE2 1 
ATOM   3636  C CZ  . PHE A 1 540 ? 140.983 122.231 148.176 1.00 33.03  ? 540 PHE A CZ  1 
ATOM   3637  N N   . LEU A 1 541 ? 142.756 117.862 146.421 1.00 19.20  ? 541 LEU A N   1 
ATOM   3638  C CA  . LEU A 1 541 ? 142.852 117.277 147.746 1.00 28.68  ? 541 LEU A CA  1 
ATOM   3639  C C   . LEU A 1 541 ? 144.263 116.786 148.068 1.00 29.19  ? 541 LEU A C   1 
ATOM   3640  O O   . LEU A 1 541 ? 144.723 116.990 149.179 1.00 37.90  ? 541 LEU A O   1 
ATOM   3641  C CB  . LEU A 1 541 ? 141.807 116.156 147.868 1.00 33.04  ? 541 LEU A CB  1 
ATOM   3642  C CG  . LEU A 1 541 ? 141.740 115.487 149.246 1.00 32.91  ? 541 LEU A CG  1 
ATOM   3643  C CD1 . LEU A 1 541 ? 141.200 116.441 150.310 1.00 30.39  ? 541 LEU A CD1 1 
ATOM   3644  C CD2 . LEU A 1 541 ? 140.818 114.280 149.168 1.00 32.93  ? 541 LEU A CD2 1 
ATOM   3645  N N   . LEU A 1 542 ? 144.996 116.216 147.108 1.00 26.34  ? 542 LEU A N   1 
ATOM   3646  C CA  . LEU A 1 542 ? 146.394 115.842 147.298 1.00 22.34  ? 542 LEU A CA  1 
ATOM   3647  C C   . LEU A 1 542 ? 147.267 117.041 147.693 1.00 20.49  ? 542 LEU A C   1 
ATOM   3648  O O   . LEU A 1 542 ? 147.995 116.979 148.676 1.00 32.24  ? 542 LEU A O   1 
ATOM   3649  C CB  . LEU A 1 542 ? 146.892 115.150 146.015 1.00 28.65  ? 542 LEU A CB  1 
ATOM   3650  C CG  . LEU A 1 542 ? 148.371 114.729 146.033 1.00 29.21  ? 542 LEU A CG  1 
ATOM   3651  C CD1 . LEU A 1 542 ? 148.659 113.667 147.085 1.00 31.51  ? 542 LEU A CD1 1 
ATOM   3652  C CD2 . LEU A 1 542 ? 148.749 114.165 144.673 1.00 23.63  ? 542 LEU A CD2 1 
ATOM   3653  N N   . VAL A 1 543 ? 147.162 118.158 146.975 1.00 21.26  ? 543 VAL A N   1 
ATOM   3654  C CA  . VAL A 1 543 ? 147.908 119.383 147.294 1.00 19.67  ? 543 VAL A CA  1 
ATOM   3655  C C   . VAL A 1 543 ? 147.467 119.970 148.631 1.00 21.93  ? 543 VAL A C   1 
ATOM   3656  O O   . VAL A 1 543 ? 148.302 120.293 149.473 1.00 30.93  ? 543 VAL A O   1 
ATOM   3657  C CB  . VAL A 1 543 ? 147.774 120.428 146.170 1.00 22.11  ? 543 VAL A CB  1 
ATOM   3658  C CG1 . VAL A 1 543 ? 148.606 121.674 146.459 1.00 20.68  ? 543 VAL A CG1 1 
ATOM   3659  C CG2 . VAL A 1 543 ? 148.244 119.843 144.840 1.00 24.61  ? 543 VAL A CG2 1 
ATOM   3660  N N   . TYR A 1 544 ? 146.158 120.056 148.857 1.00 29.66  ? 544 TYR A N   1 
ATOM   3661  C CA  . TYR A 1 544 ? 145.593 120.568 150.091 1.00 11.40  ? 544 TYR A CA  1 
ATOM   3662  C C   . TYR A 1 544 ? 145.987 119.745 151.325 1.00 14.48  ? 544 TYR A C   1 
ATOM   3663  O O   . TYR A 1 544 ? 146.319 120.324 152.350 1.00 29.68  ? 544 TYR A O   1 
ATOM   3664  C CB  . TYR A 1 544 ? 144.074 120.710 149.971 1.00 19.05  ? 544 TYR A CB  1 
ATOM   3665  C CG  . TYR A 1 544 ? 143.449 121.184 151.255 1.00 30.63  ? 544 TYR A CG  1 
ATOM   3666  C CD1 . TYR A 1 544 ? 143.505 122.517 151.618 1.00 25.03  ? 544 TYR A CD1 1 
ATOM   3667  C CD2 . TYR A 1 544 ? 142.865 120.293 152.136 1.00 23.56  ? 544 TYR A CD2 1 
ATOM   3668  C CE1 . TYR A 1 544 ? 142.970 122.959 152.813 1.00 22.27  ? 544 TYR A CE1 1 
ATOM   3669  C CE2 . TYR A 1 544 ? 142.329 120.718 153.338 1.00 16.54  ? 544 TYR A CE2 1 
ATOM   3670  C CZ  . TYR A 1 544 ? 142.376 122.056 153.673 1.00 28.73  ? 544 TYR A CZ  1 
ATOM   3671  O OH  . TYR A 1 544 ? 141.842 122.486 154.849 1.00 39.08  ? 544 TYR A OH  1 
ATOM   3672  N N   . LEU A 1 545 ? 145.992 118.414 151.259 1.00 10.84  ? 545 LEU A N   1 
ATOM   3673  C CA  . LEU A 1 545 ? 146.378 117.575 152.394 1.00 16.93  ? 545 LEU A CA  1 
ATOM   3674  C C   . LEU A 1 545 ? 147.873 117.646 152.699 1.00 17.13  ? 545 LEU A C   1 
ATOM   3675  O O   . LEU A 1 545 ? 148.257 117.571 153.861 1.00 27.95  ? 545 LEU A O   1 
ATOM   3676  C CB  . LEU A 1 545 ? 145.928 116.128 152.164 1.00 24.28  ? 545 LEU A CB  1 
ATOM   3677  C CG  . LEU A 1 545 ? 144.408 115.899 152.237 1.00 26.90  ? 545 LEU A CG  1 
ATOM   3678  C CD1 . LEU A 1 545 ? 144.135 114.418 152.003 1.00 26.33  ? 545 LEU A CD1 1 
ATOM   3679  C CD2 . LEU A 1 545 ? 143.795 116.294 153.576 1.00 18.91  ? 545 LEU A CD2 1 
ATOM   3680  N N   . VAL A 1 546 ? 148.730 117.854 151.700 1.00 26.76  ? 546 VAL A N   1 
ATOM   3681  C CA  . VAL A 1 546 ? 150.151 118.143 151.932 1.00 17.52  ? 546 VAL A CA  1 
ATOM   3682  C C   . VAL A 1 546 ? 150.333 119.485 152.644 1.00 24.60  ? 546 VAL A C   1 
ATOM   3683  O O   . VAL A 1 546 ? 151.096 119.549 153.603 1.00 32.21  ? 546 VAL A O   1 
ATOM   3684  C CB  . VAL A 1 546 ? 150.952 118.060 150.622 1.00 22.01  ? 546 VAL A CB  1 
ATOM   3685  C CG1 . VAL A 1 546 ? 152.387 118.557 150.785 1.00 19.88  ? 546 VAL A CG1 1 
ATOM   3686  C CG2 . VAL A 1 546 ? 151.028 116.609 150.147 1.00 21.98  ? 546 VAL A CG2 1 
ATOM   3687  N N   . PHE A 1 547 ? 149.606 120.534 152.246 1.00 26.33  ? 547 PHE A N   1 
ATOM   3688  C CA  . PHE A 1 547 ? 149.655 121.822 152.988 1.00 13.54  ? 547 PHE A CA  1 
ATOM   3689  C C   . PHE A 1 547 ? 149.104 121.611 154.403 1.00 18.12  ? 547 PHE A C   1 
ATOM   3690  O O   . PHE A 1 547 ? 149.778 121.994 155.350 1.00 34.33  ? 547 PHE A O   1 
ATOM   3691  C CB  . PHE A 1 547 ? 148.874 122.905 152.238 1.00 18.05  ? 547 PHE A CB  1 
ATOM   3692  C CG  . PHE A 1 547 ? 149.614 123.539 151.086 1.00 23.53  ? 547 PHE A CG  1 
ATOM   3693  C CD1 . PHE A 1 547 ? 149.771 122.864 149.887 1.00 30.28  ? 547 PHE A CD1 1 
ATOM   3694  C CD2 . PHE A 1 547 ? 150.148 124.812 151.201 1.00 34.62  ? 547 PHE A CD2 1 
ATOM   3695  C CE1 . PHE A 1 547 ? 150.452 123.447 148.828 1.00 29.57  ? 547 PHE A CE1 1 
ATOM   3696  C CE2 . PHE A 1 547 ? 150.826 125.394 150.142 1.00 30.59  ? 547 PHE A CE2 1 
ATOM   3697  C CZ  . PHE A 1 547 ? 150.977 124.711 148.958 1.00 24.93  ? 547 PHE A CZ  1 
ATOM   3698  N N   . LEU A 1 548 ? 147.943 120.980 154.570 1.00 25.17  ? 548 LEU A N   1 
ATOM   3699  C CA  . LEU A 1 548 ? 147.312 120.737 155.858 1.00 16.53  ? 548 LEU A CA  1 
ATOM   3700  C C   . LEU A 1 548 ? 148.239 120.002 156.820 1.00 15.31  ? 548 LEU A C   1 
ATOM   3701  O O   . LEU A 1 548 ? 148.518 120.501 157.904 1.00 33.86  ? 548 LEU A O   1 
ATOM   3702  C CB  . LEU A 1 548 ? 146.009 119.958 155.626 1.00 26.07  ? 548 LEU A CB  1 
ATOM   3703  C CG  . LEU A 1 548 ? 145.205 119.697 156.907 1.00 29.16  ? 548 LEU A CG  1 
ATOM   3704  C CD1 . LEU A 1 548 ? 144.619 120.997 157.436 1.00 22.31  ? 548 LEU A CD1 1 
ATOM   3705  C CD2 . LEU A 1 548 ? 144.075 118.720 156.622 1.00 26.04  ? 548 LEU A CD2 1 
ATOM   3706  N N   . PHE A 1 549 ? 148.747 118.831 156.447 1.00 20.69  ? 549 PHE A N   1 
ATOM   3707  C CA  . PHE A 1 549 ? 149.564 118.037 157.350 1.00 22.94  ? 549 PHE A CA  1 
ATOM   3708  C C   . PHE A 1 549 ? 150.974 118.598 157.540 1.00 21.46  ? 549 PHE A C   1 
ATOM   3709  O O   . PHE A 1 549 ? 151.480 118.545 158.656 1.00 37.55  ? 549 PHE A O   1 
ATOM   3710  C CB  . PHE A 1 549 ? 149.547 116.567 156.921 1.00 23.52  ? 549 PHE A CB  1 
ATOM   3711  C CG  . PHE A 1 549 ? 148.156 115.948 156.896 1.00 32.21  ? 549 PHE A CG  1 
ATOM   3712  C CD1 . PHE A 1 549 ? 147.254 116.151 157.961 1.00 28.05  ? 549 PHE A CD1 1 
ATOM   3713  C CD2 . PHE A 1 549 ? 147.759 115.152 155.808 1.00 35.09  ? 549 PHE A CD2 1 
ATOM   3714  C CE1 . PHE A 1 549 ? 145.970 115.589 157.925 1.00 26.13  ? 549 PHE A CE1 1 
ATOM   3715  C CE2 . PHE A 1 549 ? 146.474 114.584 155.776 1.00 30.84  ? 549 PHE A CE2 1 
ATOM   3716  C CZ  . PHE A 1 549 ? 145.578 114.806 156.828 1.00 27.61  ? 549 PHE A CZ  1 
ATOM   3717  N N   . GLY A 1 550 ? 151.579 119.218 156.525 1.00 17.43  ? 550 GLY A N   1 
ATOM   3718  C CA  . GLY A 1 550 ? 152.858 119.910 156.657 1.00 14.65  ? 550 GLY A CA  1 
ATOM   3719  C C   . GLY A 1 550 ? 152.814 121.057 157.667 1.00 22.20  ? 550 GLY A C   1 
ATOM   3720  O O   . GLY A 1 550 ? 153.672 121.135 158.543 1.00 32.42  ? 550 GLY A O   1 
ATOM   3721  N N   . PHE A 1 551 ? 151.792 121.917 157.613 1.00 19.87  ? 551 PHE A N   1 
ATOM   3722  C CA  . PHE A 1 551 ? 151.608 122.963 158.615 1.00 11.81  ? 551 PHE A CA  1 
ATOM   3723  C C   . PHE A 1 551 ? 151.098 122.427 159.963 1.00 15.32  ? 551 PHE A C   1 
ATOM   3724  O O   . PHE A 1 551 ? 151.475 122.969 160.995 1.00 26.23  ? 551 PHE A O   1 
ATOM   3725  C CB  . PHE A 1 551 ? 150.720 124.079 158.056 1.00 10.67  ? 551 PHE A CB  1 
ATOM   3726  C CG  . PHE A 1 551 ? 151.447 125.061 157.161 1.00 12.88  ? 551 PHE A CG  1 
ATOM   3727  C CD1 . PHE A 1 551 ? 152.089 126.175 157.728 1.00 12.08  ? 551 PHE A CD1 1 
ATOM   3728  C CD2 . PHE A 1 551 ? 151.456 124.907 155.762 1.00 11.13  ? 551 PHE A CD2 1 
ATOM   3729  C CE1 . PHE A 1 551 ? 152.714 127.126 156.912 1.00 12.39  ? 551 PHE A CE1 1 
ATOM   3730  C CE2 . PHE A 1 551 ? 152.072 125.858 154.946 1.00 7.38   ? 551 PHE A CE2 1 
ATOM   3731  C CZ  . PHE A 1 551 ? 152.700 126.976 155.518 1.00 17.30  ? 551 PHE A CZ  1 
ATOM   3732  N N   . ALA A 1 552 ? 150.314 121.348 160.013 1.00 21.79  ? 552 ALA A N   1 
ATOM   3733  C CA  . ALA A 1 552 ? 149.894 120.746 161.273 1.00 18.96  ? 552 ALA A CA  1 
ATOM   3734  C C   . ALA A 1 552 ? 151.070 120.179 162.086 1.00 24.72  ? 552 ALA A C   1 
ATOM   3735  O O   . ALA A 1 552 ? 151.180 120.487 163.269 1.00 32.93  ? 552 ALA A O   1 
ATOM   3736  C CB  . ALA A 1 552 ? 148.837 119.672 161.008 1.00 20.55  ? 552 ALA A CB  1 
ATOM   3737  N N   . VAL A 1 553 ? 151.985 119.404 161.484 1.00 27.90  ? 553 VAL A N   1 
ATOM   3738  C CA  . VAL A 1 553 ? 153.170 118.895 162.203 1.00 23.67  ? 553 VAL A CA  1 
ATOM   3739  C C   . VAL A 1 553 ? 154.060 120.033 162.693 1.00 21.27  ? 553 VAL A C   1 
ATOM   3740  O O   . VAL A 1 553 ? 154.572 119.977 163.807 1.00 25.54  ? 553 VAL A O   1 
ATOM   3741  C CB  . VAL A 1 553 ? 153.986 117.857 161.396 1.00 23.54  ? 553 VAL A CB  1 
ATOM   3742  C CG1 . VAL A 1 553 ? 153.165 116.608 161.088 1.00 23.23  ? 553 VAL A CG1 1 
ATOM   3743  C CG2 . VAL A 1 553 ? 154.593 118.356 160.084 1.00 22.05  ? 553 VAL A CG2 1 
ATOM   3744  N N   . ALA A 1 554 ? 154.190 121.098 161.908 1.00 22.00  ? 554 ALA A N   1 
ATOM   3745  C CA  . ALA A 1 554 ? 154.954 122.286 162.256 1.00 17.02  ? 554 ALA A CA  1 
ATOM   3746  C C   . ALA A 1 554 ? 154.369 123.075 163.435 1.00 22.95  ? 554 ALA A C   1 
ATOM   3747  O O   . ALA A 1 554 ? 155.096 123.375 164.381 1.00 27.73  ? 554 ALA A O   1 
ATOM   3748  C CB  . ALA A 1 554 ? 155.046 123.135 160.999 1.00 17.90  ? 554 ALA A CB  1 
ATOM   3749  N N   . LEU A 1 555 ? 153.064 123.362 163.434 1.00 30.11  ? 555 LEU A N   1 
ATOM   3750  C CA  . LEU A 1 555 ? 152.393 124.044 164.542 1.00 24.47  ? 555 LEU A CA  1 
ATOM   3751  C C   . LEU A 1 555 ? 152.435 123.244 165.838 1.00 25.43  ? 555 LEU A C   1 
ATOM   3752  O O   . LEU A 1 555 ? 152.725 123.817 166.883 1.00 30.90  ? 555 LEU A O   1 
ATOM   3753  C CB  . LEU A 1 555 ? 150.936 124.361 164.174 1.00 26.90  ? 555 LEU A CB  1 
ATOM   3754  C CG  . LEU A 1 555 ? 150.796 125.492 163.149 1.00 28.28  ? 555 LEU A CG  1 
ATOM   3755  C CD1 . LEU A 1 555 ? 149.341 125.586 162.726 1.00 32.03  ? 555 LEU A CD1 1 
ATOM   3756  C CD2 . LEU A 1 555 ? 151.197 126.851 163.711 1.00 27.83  ? 555 LEU A CD2 1 
ATOM   3757  N N   . VAL A 1 556 ? 152.209 121.931 165.795 1.00 22.70  ? 556 VAL A N   1 
ATOM   3758  C CA  . VAL A 1 556 ? 152.309 121.083 166.989 1.00 27.39  ? 556 VAL A CA  1 
ATOM   3759  C C   . VAL A 1 556 ? 153.722 121.089 167.558 1.00 29.23  ? 556 VAL A C   1 
ATOM   3760  O O   . VAL A 1 556 ? 153.895 121.295 168.753 1.00 34.43  ? 556 VAL A O   1 
ATOM   3761  C CB  . VAL A 1 556 ? 151.834 119.652 166.697 1.00 27.41  ? 556 VAL A CB  1 
ATOM   3762  C CG1 . VAL A 1 556 ? 152.058 118.695 167.866 1.00 27.23  ? 556 VAL A CG1 1 
ATOM   3763  C CG2 . VAL A 1 556 ? 150.340 119.666 166.410 1.00 29.29  ? 556 VAL A CG2 1 
ATOM   3764  N N   . SER A 1 557 ? 154.740 120.938 166.710 1.00 35.18  ? 557 SER A N   1 
ATOM   3765  C CA  . SER A 1 557 ? 156.147 120.940 167.127 1.00 27.01  ? 557 SER A CA  1 
ATOM   3766  C C   . SER A 1 557 ? 156.573 122.259 167.774 1.00 30.70  ? 557 SER A C   1 
ATOM   3767  O O   . SER A 1 557 ? 157.258 122.260 168.791 1.00 36.43  ? 557 SER A O   1 
ATOM   3768  C CB  . SER A 1 557 ? 157.056 120.655 165.930 1.00 25.48  ? 557 SER A CB  1 
ATOM   3769  O OG  . SER A 1 557 ? 156.703 119.433 165.317 1.00 35.32  ? 557 SER A OG  1 
ATOM   3770  N N   . LEU A 1 558 ? 156.153 123.392 167.207 1.00 30.28  ? 558 LEU A N   1 
ATOM   3771  C CA  . LEU A 1 558 ? 156.562 124.713 167.663 1.00 28.12  ? 558 LEU A CA  1 
ATOM   3772  C C   . LEU A 1 558 ? 155.780 125.214 168.892 1.00 36.05  ? 558 LEU A C   1 
ATOM   3773  O O   . LEU A 1 558 ? 156.300 125.990 169.684 1.00 40.88  ? 558 LEU A O   1 
ATOM   3774  C CB  . LEU A 1 558 ? 156.459 125.663 166.462 1.00 22.27  ? 558 LEU A CB  1 
ATOM   3775  C CG  . LEU A 1 558 ? 157.226 126.978 166.627 1.00 29.64  ? 558 LEU A CG  1 
ATOM   3776  C CD1 . LEU A 1 558 ? 158.734 126.779 166.784 1.00 31.65  ? 558 LEU A CD1 1 
ATOM   3777  C CD2 . LEU A 1 558 ? 157.017 127.826 165.385 1.00 30.92  ? 558 LEU A CD2 1 
ATOM   3778  N N   . SER A 1 559 ? 154.556 124.729 169.103 1.00 41.73  ? 559 SER A N   1 
ATOM   3779  C CA  . SER A 1 559 ? 153.698 125.096 170.242 1.00 35.44  ? 559 SER A CA  1 
ATOM   3780  C C   . SER A 1 559 ? 153.995 124.329 171.540 1.00 42.84  ? 559 SER A C   1 
ATOM   3781  O O   . SER A 1 559 ? 153.327 124.554 172.548 1.00 50.01  ? 559 SER A O   1 
ATOM   3782  C CB  . SER A 1 559 ? 152.225 124.919 169.875 1.00 38.85  ? 559 SER A CB  1 
ATOM   3783  O OG  . SER A 1 559 ? 151.949 125.596 168.671 1.00 42.50  ? 559 SER A OG  1 
ATOM   3784  N N   . ARG A 1 560 ? 154.982 123.428 171.557 1.00 46.05  ? 560 ARG A N   1 
ATOM   3785  C CA  . ARG A 1 560 ? 155.390 122.668 172.756 1.00 46.31  ? 560 ARG A CA  1 
ATOM   3786  C C   . ARG A 1 560 ? 155.945 123.540 173.883 1.00 50.34  ? 560 ARG A C   1 
ATOM   3787  O O   . ARG A 1 560 ? 155.894 123.146 175.044 1.00 53.44  ? 560 ARG A O   1 
ATOM   3788  C CB  . ARG A 1 560 ? 156.477 121.655 172.375 1.00 46.41  ? 560 ARG A CB  1 
ATOM   3789  C CG  . ARG A 1 560 ? 155.986 120.513 171.491 1.00 44.38  ? 560 ARG A CG  1 
ATOM   3790  C CD  . ARG A 1 560 ? 155.157 119.493 172.272 1.00 47.20  ? 560 ARG A CD  1 
ATOM   3791  N NE  . ARG A 1 560 ? 154.544 118.478 171.396 1.00 52.18  ? 560 ARG A NE  1 
ATOM   3792  C CZ  . ARG A 1 560 ? 155.158 117.569 170.670 1.00 48.53  ? 560 ARG A CZ  1 
ATOM   3793  N NH1 . ARG A 1 560 ? 154.476 116.695 169.995 1.00 46.96  ? 560 ARG A NH1 1 
ATOM   3794  N NH2 . ARG A 1 560 ? 156.452 117.491 170.613 1.00 47.72  ? 560 ARG A NH2 1 
ATOM   3795  N N   . GLU A 1 561 ? 156.499 124.699 173.543 1.00 52.51  ? 561 GLU A N   1 
ATOM   3796  C CA  . GLU A 1 561 ? 157.190 125.585 174.473 1.00 54.27  ? 561 GLU A CA  1 
ATOM   3797  C C   . GLU A 1 561 ? 156.313 126.762 174.913 1.00 58.06  ? 561 GLU A C   1 
ATOM   3798  O O   . GLU A 1 561 ? 155.839 127.545 174.092 1.00 56.00  ? 561 GLU A O   1 
ATOM   3799  C CB  . GLU A 1 561 ? 158.474 126.105 173.803 1.00 55.99  ? 561 GLU A CB  1 
ATOM   3800  C CG  . GLU A 1 561 ? 159.574 125.044 173.642 1.00 57.52  ? 561 GLU A CG  1 
ATOM   3801  C CD  . GLU A 1 561 ? 160.060 124.460 174.978 1.00 60.26  ? 561 GLU A CD  1 
ATOM   3802  O OE1 . GLU A 1 561 ? 159.958 125.147 176.019 1.00 60.36  ? 561 GLU A OE1 1 
ATOM   3803  O OE2 . GLU A 1 561 ? 160.558 123.313 174.979 1.00 60.18  ? 561 GLU A OE2 1 
ATOM   3804  N N   . ALA A 1 562 ? 156.120 126.921 176.225 1.00 61.93  ? 562 ALA A N   1 
ATOM   3805  C CA  . ALA A 1 562 ? 155.417 128.051 176.820 1.00 60.80  ? 562 ALA A CA  1 
ATOM   3806  C C   . ALA A 1 562 ? 156.347 129.248 177.120 1.00 59.90  ? 562 ALA A C   1 
ATOM   3807  O O   . ALA A 1 562 ? 157.553 129.079 177.298 1.00 62.46  ? 562 ALA A O   1 
ATOM   3808  C CB  . ALA A 1 562 ? 154.701 127.556 178.076 1.00 59.37  ? 562 ALA A CB  1 
ATOM   3809  N N   . ARG A 1 563 ? 155.788 130.453 177.220 1.00 59.73  ? 563 ARG A N   1 
ATOM   3810  C CA  . ARG A 1 563 ? 156.501 131.676 177.606 1.00 62.22  ? 563 ARG A CA  1 
ATOM   3811  C C   . ARG A 1 563 ? 155.596 132.699 178.304 1.00 64.54  ? 563 ARG A C   1 
ATOM   3812  O O   . ARG A 1 563 ? 154.393 132.780 178.042 1.00 64.27  ? 563 ARG A O   1 
ATOM   3813  C CB  . ARG A 1 563 ? 157.136 132.318 176.376 1.00 59.90  ? 563 ARG A CB  1 
ATOM   3814  N N   . PRO A 1 589 ? 145.590 124.488 171.890 1.00 54.87  ? 589 PRO A N   1 
ATOM   3815  C CA  . PRO A 1 589 ? 146.997 124.842 172.018 1.00 54.32  ? 589 PRO A CA  1 
ATOM   3816  C C   . PRO A 1 589 ? 147.913 124.162 170.991 1.00 51.55  ? 589 PRO A C   1 
ATOM   3817  O O   . PRO A 1 589 ? 149.126 124.127 171.184 1.00 53.95  ? 589 PRO A O   1 
ATOM   3818  C CB  . PRO A 1 589 ? 147.369 124.475 173.459 1.00 50.66  ? 589 PRO A CB  1 
ATOM   3819  C CG  . PRO A 1 589 ? 146.047 124.570 174.209 1.00 48.34  ? 589 PRO A CG  1 
ATOM   3820  C CD  . PRO A 1 589 ? 145.047 124.081 173.167 1.00 52.58  ? 589 PRO A CD  1 
ATOM   3821  N N   . TYR A 1 590 ? 147.341 123.568 169.938 1.00 40.57  ? 590 TYR A N   1 
ATOM   3822  C CA  . TYR A 1 590 ? 148.005 122.661 168.989 1.00 37.04  ? 590 TYR A CA  1 
ATOM   3823  C C   . TYR A 1 590 ? 148.645 121.459 169.704 1.00 39.51  ? 590 TYR A C   1 
ATOM   3824  O O   . TYR A 1 590 ? 149.844 121.213 169.608 1.00 43.89  ? 590 TYR A O   1 
ATOM   3825  C CB  . TYR A 1 590 ? 148.962 123.418 168.054 1.00 36.79  ? 590 TYR A CB  1 
ATOM   3826  C CG  . TYR A 1 590 ? 148.332 124.617 167.382 1.00 36.66  ? 590 TYR A CG  1 
ATOM   3827  C CD1 . TYR A 1 590 ? 147.306 124.415 166.445 1.00 38.44  ? 590 TYR A CD1 1 
ATOM   3828  C CD2 . TYR A 1 590 ? 148.715 125.925 167.727 1.00 38.44  ? 590 TYR A CD2 1 
ATOM   3829  C CE1 . TYR A 1 590 ? 146.658 125.507 165.854 1.00 35.87  ? 590 TYR A CE1 1 
ATOM   3830  C CE2 . TYR A 1 590 ? 148.061 127.025 167.148 1.00 40.32  ? 590 TYR A CE2 1 
ATOM   3831  C CZ  . TYR A 1 590 ? 147.026 126.816 166.216 1.00 39.25  ? 590 TYR A CZ  1 
ATOM   3832  O OH  . TYR A 1 590 ? 146.351 127.865 165.690 1.00 47.47  ? 590 TYR A OH  1 
ATOM   3833  N N   . ARG A 1 591 ? 147.850 120.721 170.476 1.00 39.79  ? 591 ARG A N   1 
ATOM   3834  C CA  . ARG A 1 591 ? 148.341 119.651 171.347 1.00 40.13  ? 591 ARG A CA  1 
ATOM   3835  C C   . ARG A 1 591 ? 148.610 118.317 170.631 1.00 39.55  ? 591 ARG A C   1 
ATOM   3836  O O   . ARG A 1 591 ? 149.382 117.494 171.119 1.00 44.83  ? 591 ARG A O   1 
ATOM   3837  C CB  . ARG A 1 591 ? 147.313 119.449 172.453 1.00 39.14  ? 591 ARG A CB  1 
ATOM   3838  N N   . SER A 1 592 ? 147.990 118.083 169.477 1.00 32.75  ? 592 SER A N   1 
ATOM   3839  C CA  . SER A 1 592 ? 148.078 116.848 168.695 1.00 32.74  ? 592 SER A CA  1 
ATOM   3840  C C   . SER A 1 592 ? 147.902 117.134 167.207 1.00 33.88  ? 592 SER A C   1 
ATOM   3841  O O   . SER A 1 592 ? 147.455 118.216 166.828 1.00 39.31  ? 592 SER A O   1 
ATOM   3842  C CB  . SER A 1 592 ? 147.055 115.817 169.197 1.00 40.07  ? 592 SER A CB  1 
ATOM   3843  O OG  . SER A 1 592 ? 145.729 116.150 168.830 1.00 40.96  ? 592 SER A OG  1 
ATOM   3844  N N   . ILE A 1 593 ? 148.264 116.190 166.332 1.00 32.70  ? 593 ILE A N   1 
ATOM   3845  C CA  . ILE A 1 593 ? 148.097 116.361 164.883 1.00 27.61  ? 593 ILE A CA  1 
ATOM   3846  C C   . ILE A 1 593 ? 146.618 116.483 164.506 1.00 33.02  ? 593 ILE A C   1 
ATOM   3847  O O   . ILE A 1 593 ? 146.295 117.294 163.644 1.00 37.29  ? 593 ILE A O   1 
ATOM   3848  C CB  . ILE A 1 593 ? 148.800 115.233 164.093 1.00 33.30  ? 593 ILE A CB  1 
ATOM   3849  C CG1 . ILE A 1 593 ? 150.313 115.161 164.370 1.00 34.25  ? 593 ILE A CG1 1 
ATOM   3850  C CG2 . ILE A 1 593 ? 148.566 115.361 162.576 1.00 29.16  ? 593 ILE A CG2 1 
ATOM   3851  C CD1 . ILE A 1 593 ? 151.095 116.428 164.036 1.00 34.18  ? 593 ILE A CD1 1 
ATOM   3852  N N   . LEU A 1 594 ? 145.703 115.760 165.161 1.00 36.49  ? 594 LEU A N   1 
ATOM   3853  C CA  . LEU A 1 594 ? 144.260 115.900 164.928 1.00 31.29  ? 594 LEU A CA  1 
ATOM   3854  C C   . LEU A 1 594 ? 143.759 117.288 165.344 1.00 30.72  ? 594 LEU A C   1 
ATOM   3855  O O   . LEU A 1 594 ? 143.057 117.934 164.579 1.00 37.09  ? 594 LEU A O   1 
ATOM   3856  C CB  . LEU A 1 594 ? 143.500 114.771 165.648 1.00 38.53  ? 594 LEU A CB  1 
ATOM   3857  C CG  . LEU A 1 594 ? 141.961 114.867 165.551 1.00 41.12  ? 594 LEU A CG  1 
ATOM   3858  C CD1 . LEU A 1 594 ? 141.458 114.782 164.114 1.00 38.84  ? 594 LEU A CD1 1 
ATOM   3859  C CD2 . LEU A 1 594 ? 141.316 113.741 166.343 1.00 35.80  ? 594 LEU A CD2 1 
ATOM   3860  N N   . ASP A 1 595 ? 144.171 117.772 166.515 1.00 27.66  ? 595 ASP A N   1 
ATOM   3861  C CA  . ASP A 1 595 ? 143.836 119.105 167.009 1.00 27.82  ? 595 ASP A CA  1 
ATOM   3862  C C   . ASP A 1 595 ? 144.287 120.200 166.028 1.00 31.34  ? 595 ASP A C   1 
ATOM   3863  O O   . ASP A 1 595 ? 143.472 120.989 165.559 1.00 36.15  ? 595 ASP A O   1 
ATOM   3864  C CB  . ASP A 1 595 ? 144.487 119.274 168.391 1.00 33.90  ? 595 ASP A CB  1 
ATOM   3865  C CG  . ASP A 1 595 ? 144.205 120.612 169.070 1.00 42.60  ? 595 ASP A CG  1 
ATOM   3866  O OD1 . ASP A 1 595 ? 143.045 121.070 169.049 1.00 43.02  ? 595 ASP A OD1 1 
ATOM   3867  O OD2 . ASP A 1 595 ? 145.150 121.169 169.672 1.00 43.44  ? 595 ASP A OD2 1 
ATOM   3868  N N   . ALA A 1 596 ? 145.560 120.205 165.632 1.00 30.10  ? 596 ALA A N   1 
ATOM   3869  C CA  . ALA A 1 596 ? 146.088 121.182 164.692 1.00 19.23  ? 596 ALA A CA  1 
ATOM   3870  C C   . ALA A 1 596 ? 145.522 121.044 163.275 1.00 24.64  ? 596 ALA A C   1 
ATOM   3871  O O   . ALA A 1 596 ? 145.273 122.050 162.627 1.00 31.15  ? 596 ALA A O   1 
ATOM   3872  C CB  . ALA A 1 596 ? 147.613 121.089 164.702 1.00 24.65  ? 596 ALA A CB  1 
ATOM   3873  N N   . SER A 1 597 ? 145.259 119.827 162.792 1.00 28.40  ? 597 SER A N   1 
ATOM   3874  C CA  . SER A 1 597 ? 144.606 119.620 161.493 1.00 19.72  ? 597 SER A CA  1 
ATOM   3875  C C   . SER A 1 597 ? 143.196 120.189 161.477 1.00 21.65  ? 597 SER A C   1 
ATOM   3876  O O   . SER A 1 597 ? 142.790 120.773 160.484 1.00 30.35  ? 597 SER A O   1 
ATOM   3877  C CB  . SER A 1 597 ? 144.507 118.142 161.131 1.00 23.46  ? 597 SER A CB  1 
ATOM   3878  O OG  . SER A 1 597 ? 145.785 117.570 161.056 1.00 35.54  ? 597 SER A OG  1 
ATOM   3879  N N   . LEU A 1 598 ? 142.438 120.035 162.557 1.00 22.32  ? 598 LEU A N   1 
ATOM   3880  C CA  . LEU A 1 598 ? 141.078 120.546 162.626 1.00 21.00  ? 598 LEU A CA  1 
ATOM   3881  C C   . LEU A 1 598 ? 141.055 122.076 162.743 1.00 19.07  ? 598 LEU A C   1 
ATOM   3882  O O   . LEU A 1 598 ? 140.280 122.730 162.054 1.00 24.35  ? 598 LEU A O   1 
ATOM   3883  C CB  . LEU A 1 598 ? 140.343 119.815 163.757 1.00 26.83  ? 598 LEU A CB  1 
ATOM   3884  C CG  . LEU A 1 598 ? 138.819 119.942 163.671 1.00 30.36  ? 598 LEU A CG  1 
ATOM   3885  C CD1 . LEU A 1 598 ? 138.274 119.206 162.448 1.00 20.74  ? 598 LEU A CD1 1 
ATOM   3886  C CD2 . LEU A 1 598 ? 138.193 119.348 164.925 1.00 22.68  ? 598 LEU A CD2 1 
ATOM   3887  N N   . GLU A 1 599 ? 141.953 122.671 163.527 1.00 21.27  ? 599 GLU A N   1 
ATOM   3888  C CA  . GLU A 1 599 ? 142.147 124.123 163.562 1.00 14.57  ? 599 GLU A CA  1 
ATOM   3889  C C   . GLU A 1 599 ? 142.579 124.709 162.215 1.00 21.83  ? 599 GLU A C   1 
ATOM   3890  O O   . GLU A 1 599 ? 142.044 125.731 161.791 1.00 33.85  ? 599 GLU A O   1 
ATOM   3891  C CB  . GLU A 1 599 ? 143.181 124.494 164.636 1.00 25.85  ? 599 GLU A CB  1 
ATOM   3892  C CG  . GLU A 1 599 ? 142.702 124.298 166.080 1.00 24.81  ? 599 GLU A CG  1 
ATOM   3893  C CD  . GLU A 1 599 ? 141.372 124.995 166.389 1.00 36.56  ? 599 GLU A CD  1 
ATOM   3894  O OE1 . GLU A 1 599 ? 141.164 126.139 165.937 1.00 36.58  ? 599 GLU A OE1 1 
ATOM   3895  O OE2 . GLU A 1 599 ? 140.505 124.394 167.059 1.00 37.37  ? 599 GLU A OE2 1 
ATOM   3896  N N   . LEU A 1 600 ? 143.491 124.062 161.492 1.00 23.09  ? 600 LEU A N   1 
ATOM   3897  C CA  . LEU A 1 600 ? 143.863 124.477 160.146 1.00 7.60   ? 600 LEU A CA  1 
ATOM   3898  C C   . LEU A 1 600 ? 142.743 124.277 159.126 1.00 7.70   ? 600 LEU A C   1 
ATOM   3899  O O   . LEU A 1 600 ? 142.578 125.102 158.228 1.00 27.63  ? 600 LEU A O   1 
ATOM   3900  C CB  . LEU A 1 600 ? 145.116 123.722 159.698 1.00 20.99  ? 600 LEU A CB  1 
ATOM   3901  C CG  . LEU A 1 600 ? 146.424 124.170 160.358 1.00 7.03   ? 600 LEU A CG  1 
ATOM   3902  C CD1 . LEU A 1 600 ? 147.563 123.401 159.722 1.00 14.06  ? 600 LEU A CD1 1 
ATOM   3903  C CD2 . LEU A 1 600 ? 146.689 125.651 160.165 1.00 13.98  ? 600 LEU A CD2 1 
ATOM   3904  N N   . PHE A 1 601 ? 141.956 123.211 159.226 1.00 18.83  ? 601 PHE A N   1 
ATOM   3905  C CA  . PHE A 1 601 ? 140.822 122.985 158.341 1.00 16.41  ? 601 PHE A CA  1 
ATOM   3906  C C   . PHE A 1 601 ? 139.711 124.032 158.533 1.00 16.51  ? 601 PHE A C   1 
ATOM   3907  O O   . PHE A 1 601 ? 139.095 124.468 157.562 1.00 14.51  ? 601 PHE A O   1 
ATOM   3908  C CB  . PHE A 1 601 ? 140.306 121.553 158.519 1.00 14.10  ? 601 PHE A CB  1 
ATOM   3909  C CG  . PHE A 1 601 ? 139.167 121.235 157.577 1.00 17.13  ? 601 PHE A CG  1 
ATOM   3910  C CD1 . PHE A 1 601 ? 139.416 121.107 156.199 1.00 19.85  ? 601 PHE A CD1 1 
ATOM   3911  C CD2 . PHE A 1 601 ? 137.851 121.158 158.055 1.00 15.76  ? 601 PHE A CD2 1 
ATOM   3912  C CE1 . PHE A 1 601 ? 138.356 120.925 155.304 1.00 18.40  ? 601 PHE A CE1 1 
ATOM   3913  C CE2 . PHE A 1 601 ? 136.791 120.966 157.160 1.00 19.77  ? 601 PHE A CE2 1 
ATOM   3914  C CZ  . PHE A 1 601 ? 137.040 120.853 155.786 1.00 18.40  ? 601 PHE A CZ  1 
ATOM   3915  N N   . LYS A 1 602 ? 139.511 124.525 159.761 1.00 22.08  ? 602 LYS A N   1 
ATOM   3916  C CA  . LYS A 1 602 ? 138.524 125.562 160.077 1.00 9.24   ? 602 LYS A CA  1 
ATOM   3917  C C   . LYS A 1 602 ? 138.668 126.856 159.280 1.00 11.40  ? 602 LYS A C   1 
ATOM   3918  O O   . LYS A 1 602 ? 137.660 127.496 159.003 1.00 26.61  ? 602 LYS A O   1 
ATOM   3919  C CB  . LYS A 1 602 ? 138.472 125.815 161.590 1.00 8.83   ? 602 LYS A CB  1 
ATOM   3920  C CG  . LYS A 1 602 ? 137.522 124.790 162.214 1.00 13.86  ? 602 LYS A CG  1 
ATOM   3921  C CD  . LYS A 1 602 ? 137.213 125.032 163.688 1.00 17.19  ? 602 LYS A CD  1 
ATOM   3922  C CE  . LYS A 1 602 ? 138.380 124.666 164.591 1.00 13.84  ? 602 LYS A CE  1 
ATOM   3923  N NZ  . LYS A 1 602 ? 137.960 124.610 166.009 1.00 27.33  ? 602 LYS A NZ  1 
ATOM   3924  N N   . PHE A 1 603 ? 139.854 127.214 158.802 1.00 19.17  ? 603 PHE A N   1 
ATOM   3925  C CA  . PHE A 1 603 ? 140.030 128.340 157.884 1.00 19.97  ? 603 PHE A CA  1 
ATOM   3926  C C   . PHE A 1 603 ? 139.289 128.180 156.552 1.00 22.43  ? 603 PHE A C   1 
ATOM   3927  O O   . PHE A 1 603 ? 138.840 129.168 155.984 1.00 30.66  ? 603 PHE A O   1 
ATOM   3928  C CB  . PHE A 1 603 ? 141.518 128.567 157.628 1.00 9.82   ? 603 PHE A CB  1 
ATOM   3929  C CG  . PHE A 1 603 ? 142.246 129.135 158.818 1.00 14.63  ? 603 PHE A CG  1 
ATOM   3930  C CD1 . PHE A 1 603 ? 142.237 130.521 159.040 1.00 15.60  ? 603 PHE A CD1 1 
ATOM   3931  C CD2 . PHE A 1 603 ? 142.916 128.296 159.719 1.00 10.91  ? 603 PHE A CD2 1 
ATOM   3932  C CE1 . PHE A 1 603 ? 142.893 131.047 160.156 1.00 14.42  ? 603 PHE A CE1 1 
ATOM   3933  C CE2 . PHE A 1 603 ? 143.574 128.827 160.835 1.00 12.25  ? 603 PHE A CE2 1 
ATOM   3934  C CZ  . PHE A 1 603 ? 143.563 130.208 161.057 1.00 16.30  ? 603 PHE A CZ  1 
ATOM   3935  N N   . THR A 1 604 ? 139.106 126.959 156.055 1.00 26.75  ? 604 THR A N   1 
ATOM   3936  C CA  . THR A 1 604 ? 138.403 126.710 154.787 1.00 15.06  ? 604 THR A CA  1 
ATOM   3937  C C   . THR A 1 604 ? 136.882 126.864 154.894 1.00 13.86  ? 604 THR A C   1 
ATOM   3938  O O   . THR A 1 604 ? 136.220 127.095 153.889 1.00 28.67  ? 604 THR A O   1 
ATOM   3939  C CB  . THR A 1 604 ? 138.744 125.329 154.213 1.00 26.86  ? 604 THR A CB  1 
ATOM   3940  O OG1 . THR A 1 604 ? 138.183 124.300 154.987 1.00 32.71  ? 604 THR A OG1 1 
ATOM   3941  C CG2 . THR A 1 604 ? 140.247 125.088 154.116 1.00 23.28  ? 604 THR A CG2 1 
ATOM   3942  N N   . ILE A 1 605 ? 136.327 126.781 156.104 1.00 17.95  ? 605 ILE A N   1 
ATOM   3943  C CA  . ILE A 1 605 ? 134.894 126.909 156.392 1.00 15.20  ? 605 ILE A CA  1 
ATOM   3944  C C   . ILE A 1 605 ? 134.529 128.254 157.047 1.00 15.06  ? 605 ILE A C   1 
ATOM   3945  O O   . ILE A 1 605 ? 133.430 128.422 157.560 1.00 26.29  ? 605 ILE A O   1 
ATOM   3946  C CB  . ILE A 1 605 ? 134.368 125.687 157.172 1.00 11.53  ? 605 ILE A CB  1 
ATOM   3947  C CG1 . ILE A 1 605 ? 135.018 125.545 158.555 1.00 14.17  ? 605 ILE A CG1 1 
ATOM   3948  C CG2 . ILE A 1 605 ? 134.544 124.397 156.370 1.00 12.61  ? 605 ILE A CG2 1 
ATOM   3949  C CD1 . ILE A 1 605 ? 134.170 124.757 159.542 1.00 10.18  ? 605 ILE A CD1 1 
ATOM   3950  N N   . GLY A 1 606 ? 135.444 129.223 157.045 1.00 10.51  ? 606 GLY A N   1 
ATOM   3951  C CA  . GLY A 1 606 ? 135.224 130.553 157.607 1.00 0.00   ? 606 GLY A CA  1 
ATOM   3952  C C   . GLY A 1 606 ? 135.280 130.635 159.132 1.00 3.54   ? 606 GLY A C   1 
ATOM   3953  O O   . GLY A 1 606 ? 134.705 131.550 159.692 1.00 26.13  ? 606 GLY A O   1 
ATOM   3954  N N   . MET A 1 607 ? 135.951 129.700 159.807 1.00 15.85  ? 607 MET A N   1 
ATOM   3955  C CA  . MET A 1 607 ? 135.947 129.551 161.269 1.00 0.83   ? 607 MET A CA  1 
ATOM   3956  C C   . MET A 1 607 ? 137.335 129.535 161.926 1.00 13.35  ? 607 MET A C   1 
ATOM   3957  O O   . MET A 1 607 ? 137.460 129.193 163.097 1.00 15.20  ? 607 MET A O   1 
ATOM   3958  C CB  . MET A 1 607 ? 135.133 128.302 161.638 1.00 16.92  ? 607 MET A CB  1 
ATOM   3959  C CG  . MET A 1 607 ? 133.634 128.538 161.480 1.00 0.00   ? 607 MET A CG  1 
ATOM   3960  S SD  . MET A 1 607 ? 132.900 129.622 162.736 1.00 23.99  ? 607 MET A SD  1 
ATOM   3961  C CE  . MET A 1 607 ? 132.967 128.587 164.205 1.00 9.31   ? 607 MET A CE  1 
ATOM   3962  N N   . GLY A 1 608 ? 138.398 129.866 161.190 1.00 13.82  ? 608 GLY A N   1 
ATOM   3963  C CA  . GLY A 1 608 ? 139.776 129.759 161.665 1.00 5.67   ? 608 GLY A CA  1 
ATOM   3964  C C   . GLY A 1 608 ? 140.194 130.851 162.648 1.00 17.97  ? 608 GLY A C   1 
ATOM   3965  O O   . GLY A 1 608 ? 140.076 132.034 162.367 1.00 30.12  ? 608 GLY A O   1 
ATOM   3966  N N   . GLU A 1 609 ? 140.730 130.479 163.803 1.00 32.67  ? 609 GLU A N   1 
ATOM   3967  C CA  . GLU A 1 609 ? 141.211 131.440 164.797 1.00 28.62  ? 609 GLU A CA  1 
ATOM   3968  C C   . GLU A 1 609 ? 142.640 131.922 164.500 1.00 33.45  ? 609 GLU A C   1 
ATOM   3969  O O   . GLU A 1 609 ? 143.591 131.144 164.562 1.00 39.59  ? 609 GLU A O   1 
ATOM   3970  C CB  . GLU A 1 609 ? 141.111 130.836 166.204 1.00 31.73  ? 609 GLU A CB  1 
ATOM   3971  C CG  . GLU A 1 609 ? 139.667 130.647 166.699 1.00 36.83  ? 609 GLU A CG  1 
ATOM   3972  C CD  . GLU A 1 609 ? 138.940 131.950 167.082 1.00 47.46  ? 609 GLU A CD  1 
ATOM   3973  O OE1 . GLU A 1 609 ? 139.510 133.053 166.926 1.00 47.74  ? 609 GLU A OE1 1 
ATOM   3974  O OE2 . GLU A 1 609 ? 137.798 131.870 167.576 1.00 41.00  ? 609 GLU A OE2 1 
ATOM   3975  N N   . LEU A 1 610 ? 142.809 133.225 164.252 1.00 34.60  ? 610 LEU A N   1 
ATOM   3976  C CA  . LEU A 1 610 ? 144.104 133.911 164.303 1.00 27.87  ? 610 LEU A CA  1 
ATOM   3977  C C   . LEU A 1 610 ? 144.217 134.725 165.590 1.00 34.29  ? 610 LEU A C   1 
ATOM   3978  O O   . LEU A 1 610 ? 143.389 135.591 165.876 1.00 38.89  ? 610 LEU A O   1 
ATOM   3979  C CB  . LEU A 1 610 ? 144.295 134.877 163.127 1.00 28.23  ? 610 LEU A CB  1 
ATOM   3980  C CG  . LEU A 1 610 ? 144.398 134.244 161.746 1.00 32.26  ? 610 LEU A CG  1 
ATOM   3981  C CD1 . LEU A 1 610 ? 144.371 135.339 160.690 1.00 35.78  ? 610 LEU A CD1 1 
ATOM   3982  C CD2 . LEU A 1 610 ? 145.686 133.450 161.550 1.00 32.25  ? 610 LEU A CD2 1 
ATOM   3983  N N   . ALA A 1 611 ? 145.287 134.493 166.332 1.00 43.95  ? 611 ALA A N   1 
ATOM   3984  C CA  . ALA A 1 611 ? 145.647 135.276 167.499 1.00 42.09  ? 611 ALA A CA  1 
ATOM   3985  C C   . ALA A 1 611 ? 147.165 135.351 167.611 1.00 44.77  ? 611 ALA A C   1 
ATOM   3986  O O   . ALA A 1 611 ? 147.857 134.374 167.325 1.00 47.94  ? 611 ALA A O   1 
ATOM   3987  C CB  . ALA A 1 611 ? 145.023 134.618 168.732 1.00 39.91  ? 611 ALA A CB  1 
ATOM   3988  N N   . PHE A 1 612 ? 147.698 136.478 168.083 1.00 51.49  ? 612 PHE A N   1 
ATOM   3989  C CA  . PHE A 1 612 ? 149.049 136.520 168.629 1.00 49.69  ? 612 PHE A CA  1 
ATOM   3990  C C   . PHE A 1 612 ? 149.015 135.837 170.004 1.00 50.93  ? 612 PHE A C   1 
ATOM   3991  O O   . PHE A 1 612 ? 148.625 136.427 171.010 1.00 51.66  ? 612 PHE A O   1 
ATOM   3992  C CB  . PHE A 1 612 ? 149.531 137.971 168.654 1.00 49.42  ? 612 PHE A CB  1 
ATOM   3993  C CG  . PHE A 1 612 ? 150.987 138.129 169.023 1.00 52.15  ? 612 PHE A CG  1 
ATOM   3994  C CD1 . PHE A 1 612 ? 151.987 137.785 168.097 1.00 48.62  ? 612 PHE A CD1 1 
ATOM   3995  C CD2 . PHE A 1 612 ? 151.351 138.672 170.268 1.00 52.67  ? 612 PHE A CD2 1 
ATOM   3996  C CE1 . PHE A 1 612 ? 153.339 138.000 168.405 1.00 52.96  ? 612 PHE A CE1 1 
ATOM   3997  C CE2 . PHE A 1 612 ? 152.703 138.898 170.573 1.00 51.27  ? 612 PHE A CE2 1 
ATOM   3998  C CZ  . PHE A 1 612 ? 153.696 138.567 169.639 1.00 53.44  ? 612 PHE A CZ  1 
ATOM   3999  N N   . GLN A 1 613 ? 149.292 134.536 170.010 1.00 55.85  ? 613 GLN A N   1 
ATOM   4000  C CA  . GLN A 1 613 ? 148.940 133.622 171.096 1.00 56.87  ? 613 GLN A CA  1 
ATOM   4001  C C   . GLN A 1 613 ? 149.938 133.704 172.261 1.00 58.17  ? 613 GLN A C   1 
ATOM   4002  O O   . GLN A 1 613 ? 150.939 132.993 172.294 1.00 58.22  ? 613 GLN A O   1 
ATOM   4003  C CB  . GLN A 1 613 ? 148.797 132.224 170.476 1.00 54.32  ? 613 GLN A CB  1 
ATOM   4004  C CG  . GLN A 1 613 ? 148.076 131.234 171.394 1.00 55.43  ? 613 GLN A CG  1 
ATOM   4005  C CD  . GLN A 1 613 ? 147.363 130.130 170.619 1.00 59.42  ? 613 GLN A CD  1 
ATOM   4006  O OE1 . GLN A 1 613 ? 147.658 129.826 169.475 1.00 56.55  ? 613 GLN A OE1 1 
ATOM   4007  N NE2 . GLN A 1 613 ? 146.383 129.487 171.208 1.00 60.31  ? 613 GLN A NE2 1 
ATOM   4008  N N   . GLU A 1 614 ? 149.690 134.616 173.204 1.00 63.21  ? 614 GLU A N   1 
ATOM   4009  C CA  . GLU A 1 614 ? 150.706 135.125 174.139 1.00 61.27  ? 614 GLU A CA  1 
ATOM   4010  C C   . GLU A 1 614 ? 151.404 134.068 175.012 1.00 63.59  ? 614 GLU A C   1 
ATOM   4011  O O   . GLU A 1 614 ? 152.576 134.247 175.335 1.00 62.79  ? 614 GLU A O   1 
ATOM   4012  C CB  . GLU A 1 614 ? 150.117 136.220 175.037 1.00 60.87  ? 614 GLU A CB  1 
ATOM   4013  C CG  . GLU A 1 614 ? 149.765 137.506 174.275 1.00 60.22  ? 614 GLU A CG  1 
ATOM   4014  C CD  . GLU A 1 614 ? 149.825 138.765 175.162 1.00 64.79  ? 614 GLU A CD  1 
ATOM   4015  O OE1 . GLU A 1 614 ? 149.626 138.670 176.393 1.00 65.08  ? 614 GLU A OE1 1 
ATOM   4016  O OE2 . GLU A 1 614 ? 150.076 139.863 174.628 1.00 63.71  ? 614 GLU A OE2 1 
ATOM   4017  N N   . GLN A 1 615 ? 150.728 132.947 175.296 1.00 62.95  ? 615 GLN A N   1 
ATOM   4018  C CA  . GLN A 1 615 ? 151.275 131.909 176.225 1.00 59.32  ? 615 GLN A CA  1 
ATOM   4019  C C   . GLN A 1 615 ? 152.399 131.075 175.587 1.00 62.86  ? 615 GLN A C   1 
ATOM   4020  O O   . GLN A 1 615 ? 153.093 130.371 176.348 1.00 64.23  ? 615 GLN A O   1 
ATOM   4021  C CB  . GLN A 1 615 ? 150.129 131.013 176.711 1.00 61.20  ? 615 GLN A CB  1 
ATOM   4022  C CG  . GLN A 1 615 ? 149.515 130.117 175.620 1.00 61.61  ? 615 GLN A CG  1 
ATOM   4023  C CD  . GLN A 1 615 ? 148.438 129.208 176.160 1.00 64.79  ? 615 GLN A CD  1 
ATOM   4024  O OE1 . GLN A 1 615 ? 148.143 129.204 177.354 1.00 64.43  ? 615 GLN A OE1 1 
ATOM   4025  N NE2 . GLN A 1 615 ? 147.841 128.424 175.278 1.00 64.41  ? 615 GLN A NE2 1 
ATOM   4026  N N   . LEU A 1 616 ? 152.583 131.141 174.266 1.00 59.15  ? 616 LEU A N   1 
ATOM   4027  C CA  . LEU A 1 616 ? 153.598 130.361 173.554 1.00 53.20  ? 616 LEU A CA  1 
ATOM   4028  C C   . LEU A 1 616 ? 154.939 131.099 173.490 1.00 53.29  ? 616 LEU A C   1 
ATOM   4029  O O   . LEU A 1 616 ? 154.997 132.304 173.264 1.00 55.78  ? 616 LEU A O   1 
ATOM   4030  C CB  . LEU A 1 616 ? 153.103 130.007 172.140 1.00 55.45  ? 616 LEU A CB  1 
ATOM   4031  C CG  . LEU A 1 616 ? 151.831 129.159 172.064 1.00 55.14  ? 616 LEU A CG  1 
ATOM   4032  C CD1 . LEU A 1 616 ? 151.484 128.886 170.604 1.00 49.36  ? 616 LEU A CD1 1 
ATOM   4033  C CD2 . LEU A 1 616 ? 151.979 127.823 172.781 1.00 53.97  ? 616 LEU A CD2 1 
ATOM   4034  N N   . ARG A 1 617 ? 155.988 130.257 173.393 1.00 50.29  ? 617 ARG A N   1 
ATOM   4035  C CA  . ARG A 1 617 ? 157.343 130.742 173.041 1.00 48.29  ? 617 ARG A CA  1 
ATOM   4036  C C   . ARG A 1 617 ? 157.294 130.626 171.521 1.00 55.05  ? 617 ARG A C   1 
ATOM   4037  O O   . ARG A 1 617 ? 156.590 129.717 171.038 1.00 57.28  ? 617 ARG A O   1 
ATOM   4038  C CB  . ARG A 1 617 ? 158.394 129.802 173.629 1.00 50.25  ? 617 ARG A CB  1 
ATOM   4039  C CG  . ARG A 1 617 ? 159.847 130.274 173.533 1.00 48.10  ? 617 ARG A CG  1 
ATOM   4040  C CD  . ARG A 1 617 ? 160.713 129.192 174.183 1.00 53.85  ? 617 ARG A CD  1 
ATOM   4041  N NE  . ARG A 1 617 ? 162.128 129.525 174.244 1.00 55.88  ? 617 ARG A NE  1 
ATOM   4042  C CZ  . ARG A 1 617 ? 163.045 128.780 174.852 1.00 57.83  ? 617 ARG A CZ  1 
ATOM   4043  N NH1 . ARG A 1 617 ? 164.310 129.160 174.858 1.00 55.30  ? 617 ARG A NH1 1 
ATOM   4044  N NH2 . ARG A 1 617 ? 162.690 127.661 175.457 1.00 58.19  ? 617 ARG A NH2 1 
ATOM   4045  N N   . PHE A 1 618 ? 157.986 131.484 170.790 1.00 48.42  ? 618 PHE A N   1 
ATOM   4046  C CA  . PHE A 1 618 ? 157.895 131.540 169.321 1.00 46.14  ? 618 PHE A CA  1 
ATOM   4047  C C   . PHE A 1 618 ? 156.486 131.876 168.791 1.00 45.71  ? 618 PHE A C   1 
ATOM   4048  O O   . PHE A 1 618 ? 156.165 131.575 167.643 1.00 51.18  ? 618 PHE A O   1 
ATOM   4049  C CB  . PHE A 1 618 ? 158.493 130.281 168.665 1.00 40.68  ? 618 PHE A CB  1 
ATOM   4050  C CG  . PHE A 1 618 ? 159.780 129.772 169.270 1.00 39.63  ? 618 PHE A CG  1 
ATOM   4051  C CD1 . PHE A 1 618 ? 160.960 130.521 169.134 1.00 39.29  ? 618 PHE A CD1 1 
ATOM   4052  C CD2 . PHE A 1 618 ? 159.803 128.548 169.957 1.00 40.58  ? 618 PHE A CD2 1 
ATOM   4053  C CE1 . PHE A 1 618 ? 162.161 130.038 169.667 1.00 40.53  ? 618 PHE A CE1 1 
ATOM   4054  C CE2 . PHE A 1 618 ? 161.004 128.070 170.496 1.00 41.63  ? 618 PHE A CE2 1 
ATOM   4055  C CZ  . PHE A 1 618 ? 162.183 128.810 170.345 1.00 41.41  ? 618 PHE A CZ  1 
ATOM   4056  N N   . ARG A 1 619 ? 155.687 132.601 169.597 1.00 49.16  ? 619 ARG A N   1 
ATOM   4057  C CA  . ARG A 1 619 ? 154.282 132.987 169.231 1.00 46.22  ? 619 ARG A CA  1 
ATOM   4058  C C   . ARG A 1 619 ? 154.252 133.736 167.894 1.00 45.16  ? 619 ARG A C   1 
ATOM   4059  O O   . ARG A 1 619 ? 153.322 133.483 167.103 1.00 49.02  ? 619 ARG A O   1 
ATOM   4060  C CB  . ARG A 1 619 ? 153.645 133.730 170.420 1.00 49.60  ? 619 ARG A CB  1 
ATOM   4061  C CG  . ARG A 1 619 ? 154.408 134.983 170.872 1.00 47.42  ? 619 ARG A CG  1 
ATOM   4062  C CD  . ARG A 1 619 ? 153.763 135.556 172.132 1.00 53.03  ? 619 ARG A CD  1 
ATOM   4063  N NE  . ARG A 1 619 ? 154.340 136.850 172.467 1.00 55.32  ? 619 ARG A NE  1 
ATOM   4064  C CZ  . ARG A 1 619 ? 154.025 137.566 173.539 1.00 54.39  ? 619 ARG A CZ  1 
ATOM   4065  N NH1 . ARG A 1 619 ? 154.608 138.734 173.749 1.00 53.38  ? 619 ARG A NH1 1 
ATOM   4066  N NH2 . ARG A 1 619 ? 153.133 137.112 174.400 1.00 51.50  ? 619 ARG A NH2 1 
ATOM   4067  N N   . GLY A 1 620 ? 155.226 134.609 167.650 1.00 38.48  ? 620 GLY A N   1 
ATOM   4068  C CA  . GLY A 1 620 ? 155.329 135.354 166.395 1.00 36.24  ? 620 GLY A CA  1 
ATOM   4069  C C   . GLY A 1 620 ? 155.582 134.451 165.191 1.00 35.65  ? 620 GLY A C   1 
ATOM   4070  O O   . GLY A 1 620 ? 154.975 134.641 164.144 1.00 40.80  ? 620 GLY A O   1 
ATOM   4071  N N   . VAL A 1 621 ? 156.395 133.403 165.341 1.00 37.08  ? 621 VAL A N   1 
ATOM   4072  C CA  . VAL A 1 621 ? 156.615 132.394 164.297 1.00 35.81  ? 621 VAL A CA  1 
ATOM   4073  C C   . VAL A 1 621 ? 155.378 131.506 164.114 1.00 29.44  ? 621 VAL A C   1 
ATOM   4074  O O   . VAL A 1 621 ? 155.017 131.210 162.984 1.00 33.63  ? 621 VAL A O   1 
ATOM   4075  C CB  . VAL A 1 621 ? 157.877 131.558 164.572 1.00 35.39  ? 621 VAL A CB  1 
ATOM   4076  C CG1 . VAL A 1 621 ? 158.162 130.553 163.447 1.00 35.33  ? 621 VAL A CG1 1 
ATOM   4077  C CG2 . VAL A 1 621 ? 159.121 132.444 164.708 1.00 33.60  ? 621 VAL A CG2 1 
ATOM   4078  N N   . VAL A 1 622 ? 154.664 131.158 165.187 1.00 29.69  ? 622 VAL A N   1 
ATOM   4079  C CA  . VAL A 1 622 ? 153.366 130.463 165.117 1.00 24.91  ? 622 VAL A CA  1 
ATOM   4080  C C   . VAL A 1 622 ? 152.329 131.290 164.353 1.00 30.18  ? 622 VAL A C   1 
ATOM   4081  O O   . VAL A 1 622 ? 151.658 130.764 163.472 1.00 34.00  ? 622 VAL A O   1 
ATOM   4082  C CB  . VAL A 1 622 ? 152.882 130.080 166.528 1.00 25.76  ? 622 VAL A CB  1 
ATOM   4083  C CG1 . VAL A 1 622 ? 151.437 129.579 166.571 1.00 31.88  ? 622 VAL A CG1 1 
ATOM   4084  C CG2 . VAL A 1 622 ? 153.767 128.971 167.101 1.00 27.91  ? 622 VAL A CG2 1 
ATOM   4085  N N   . LEU A 1 623 ? 152.234 132.599 164.604 1.00 31.67  ? 623 LEU A N   1 
ATOM   4086  C CA  . LEU A 1 623 ? 151.368 133.487 163.838 1.00 24.31  ? 623 LEU A CA  1 
ATOM   4087  C C   . LEU A 1 623 ? 151.796 133.603 162.366 1.00 25.46  ? 623 LEU A C   1 
ATOM   4088  O O   . LEU A 1 623 ? 150.945 133.576 161.487 1.00 36.29  ? 623 LEU A O   1 
ATOM   4089  C CB  . LEU A 1 623 ? 151.293 134.859 164.532 1.00 32.22  ? 623 LEU A CB  1 
ATOM   4090  C CG  . LEU A 1 623 ? 150.377 135.866 163.811 1.00 33.08  ? 623 LEU A CG  1 
ATOM   4091  C CD1 . LEU A 1 623 ? 148.928 135.390 163.763 1.00 30.82  ? 623 LEU A CD1 1 
ATOM   4092  C CD2 . LEU A 1 623 ? 150.407 137.215 164.515 1.00 31.54  ? 623 LEU A CD2 1 
ATOM   4093  N N   . LEU A 1 624 ? 153.092 133.693 162.068 1.00 26.84  ? 624 LEU A N   1 
ATOM   4094  C CA  . LEU A 1 624 ? 153.581 133.706 160.691 1.00 23.45  ? 624 LEU A CA  1 
ATOM   4095  C C   . LEU A 1 624 ? 153.336 132.385 159.953 1.00 27.42  ? 624 LEU A C   1 
ATOM   4096  O O   . LEU A 1 624 ? 153.001 132.424 158.775 1.00 30.91  ? 624 LEU A O   1 
ATOM   4097  C CB  . LEU A 1 624 ? 155.071 134.082 160.663 1.00 33.65  ? 624 LEU A CB  1 
ATOM   4098  C CG  . LEU A 1 624 ? 155.353 135.552 161.006 1.00 36.55  ? 624 LEU A CG  1 
ATOM   4099  C CD1 . LEU A 1 624 ? 156.857 135.739 161.185 1.00 32.51  ? 624 LEU A CD1 1 
ATOM   4100  C CD2 . LEU A 1 624 ? 154.877 136.510 159.914 1.00 27.71  ? 624 LEU A CD2 1 
ATOM   4101  N N   . LEU A 1 625 ? 153.438 131.226 160.613 1.00 30.25  ? 625 LEU A N   1 
ATOM   4102  C CA  . LEU A 1 625 ? 153.020 129.939 160.052 1.00 19.89  ? 625 LEU A CA  1 
ATOM   4103  C C   . LEU A 1 625 ? 151.527 129.920 159.721 1.00 19.98  ? 625 LEU A C   1 
ATOM   4104  O O   . LEU A 1 625 ? 151.157 129.484 158.637 1.00 32.40  ? 625 LEU A O   1 
ATOM   4105  C CB  . LEU A 1 625 ? 153.338 128.786 161.023 1.00 30.12  ? 625 LEU A CB  1 
ATOM   4106  C CG  . LEU A 1 625 ? 154.811 128.372 161.101 1.00 28.72  ? 625 LEU A CG  1 
ATOM   4107  C CD1 . LEU A 1 625 ? 154.988 127.343 162.219 1.00 28.41  ? 625 LEU A CD1 1 
ATOM   4108  C CD2 . LEU A 1 625 ? 155.297 127.737 159.801 1.00 26.71  ? 625 LEU A CD2 1 
ATOM   4109  N N   . LEU A 1 626 ? 150.662 130.408 160.615 1.00 20.32  ? 626 LEU A N   1 
ATOM   4110  C CA  . LEU A 1 626 ? 149.229 130.512 160.350 1.00 19.10  ? 626 LEU A CA  1 
ATOM   4111  C C   . LEU A 1 626 ? 148.925 131.469 159.199 1.00 18.91  ? 626 LEU A C   1 
ATOM   4112  O O   . LEU A 1 626 ? 148.184 131.107 158.297 1.00 30.86  ? 626 LEU A O   1 
ATOM   4113  C CB  . LEU A 1 626 ? 148.482 130.950 161.615 1.00 28.01  ? 626 LEU A CB  1 
ATOM   4114  C CG  . LEU A 1 626 ? 148.402 129.871 162.696 1.00 22.99  ? 626 LEU A CG  1 
ATOM   4115  C CD1 . LEU A 1 626 ? 147.906 130.497 163.994 1.00 25.86  ? 626 LEU A CD1 1 
ATOM   4116  C CD2 . LEU A 1 626 ? 147.446 128.758 162.287 1.00 18.17  ? 626 LEU A CD2 1 
ATOM   4117  N N   . LEU A 1 627 ? 149.520 132.661 159.173 1.00 21.80  ? 627 LEU A N   1 
ATOM   4118  C CA  . LEU A 1 627 ? 149.347 133.599 158.070 1.00 17.73  ? 627 LEU A CA  1 
ATOM   4119  C C   . LEU A 1 627 ? 149.859 133.022 156.744 1.00 12.70  ? 627 LEU A C   1 
ATOM   4120  O O   . LEU A 1 627 ? 149.178 133.144 155.737 1.00 30.79  ? 627 LEU A O   1 
ATOM   4121  C CB  . LEU A 1 627 ? 150.013 134.945 158.401 1.00 22.68  ? 627 LEU A CB  1 
ATOM   4122  C CG  . LEU A 1 627 ? 149.316 135.743 159.519 1.00 25.55  ? 627 LEU A CG  1 
ATOM   4123  C CD1 . LEU A 1 627 ? 150.174 136.946 159.889 1.00 22.00  ? 627 LEU A CD1 1 
ATOM   4124  C CD2 . LEU A 1 627 ? 147.935 136.238 159.114 1.00 20.39  ? 627 LEU A CD2 1 
ATOM   4125  N N   . ALA A 1 628 ? 151.008 132.342 156.726 1.00 23.87  ? 628 ALA A N   1 
ATOM   4126  C CA  . ALA A 1 628 ? 151.493 131.632 155.548 1.00 9.93   ? 628 ALA A CA  1 
ATOM   4127  C C   . ALA A 1 628 ? 150.542 130.516 155.095 1.00 16.87  ? 628 ALA A C   1 
ATOM   4128  O O   . ALA A 1 628 ? 150.212 130.458 153.918 1.00 26.01  ? 628 ALA A O   1 
ATOM   4129  C CB  . ALA A 1 628 ? 152.893 131.093 155.822 1.00 19.84  ? 628 ALA A CB  1 
ATOM   4130  N N   . TYR A 1 629 ? 150.042 129.665 155.996 1.00 16.75  ? 629 TYR A N   1 
ATOM   4131  C CA  . TYR A 1 629 ? 149.054 128.652 155.653 1.00 6.28   ? 629 TYR A CA  1 
ATOM   4132  C C   . TYR A 1 629 ? 147.778 129.263 155.062 1.00 15.99  ? 629 TYR A C   1 
ATOM   4133  O O   . TYR A 1 629 ? 147.286 128.776 154.048 1.00 23.77  ? 629 TYR A O   1 
ATOM   4134  C CB  . TYR A 1 629 ? 148.725 127.793 156.880 1.00 5.28   ? 629 TYR A CB  1 
ATOM   4135  C CG  . TYR A 1 629 ? 147.521 126.899 156.682 1.00 15.81  ? 629 TYR A CG  1 
ATOM   4136  C CD1 . TYR A 1 629 ? 147.647 125.638 156.067 1.00 9.76   ? 629 TYR A CD1 1 
ATOM   4137  C CD2 . TYR A 1 629 ? 146.249 127.382 157.042 1.00 17.01  ? 629 TYR A CD2 1 
ATOM   4138  C CE1 . TYR A 1 629 ? 146.504 124.855 155.833 1.00 5.27   ? 629 TYR A CE1 1 
ATOM   4139  C CE2 . TYR A 1 629 ? 145.113 126.606 156.803 1.00 7.54   ? 629 TYR A CE2 1 
ATOM   4140  C CZ  . TYR A 1 629 ? 145.232 125.343 156.194 1.00 15.97  ? 629 TYR A CZ  1 
ATOM   4141  O OH  . TYR A 1 629 ? 144.118 124.594 156.022 1.00 29.31  ? 629 TYR A OH  1 
ATOM   4142  N N   . VAL A 1 630 ? 147.241 130.336 155.648 1.00 17.51  ? 630 VAL A N   1 
ATOM   4143  C CA  . VAL A 1 630 ? 146.043 131.020 155.146 1.00 18.70  ? 630 VAL A CA  1 
ATOM   4144  C C   . VAL A 1 630 ? 146.267 131.559 153.740 1.00 18.25  ? 630 VAL A C   1 
ATOM   4145  O O   . VAL A 1 630 ? 145.487 131.262 152.839 1.00 28.99  ? 630 VAL A O   1 
ATOM   4146  C CB  . VAL A 1 630 ? 145.615 132.140 156.109 1.00 26.54  ? 630 VAL A CB  1 
ATOM   4147  C CG1 . VAL A 1 630 ? 144.569 133.081 155.510 1.00 26.33  ? 630 VAL A CG1 1 
ATOM   4148  C CG2 . VAL A 1 630 ? 145.011 131.539 157.375 1.00 11.69  ? 630 VAL A CG2 1 
ATOM   4149  N N   . LEU A 1 631 ? 147.349 132.302 153.516 1.00 19.24  ? 631 LEU A N   1 
ATOM   4150  C CA  . LEU A 1 631 ? 147.661 132.872 152.211 1.00 12.55  ? 631 LEU A CA  1 
ATOM   4151  C C   . LEU A 1 631 ? 147.928 131.790 151.152 1.00 23.87  ? 631 LEU A C   1 
ATOM   4152  O O   . LEU A 1 631 ? 147.389 131.875 150.057 1.00 33.83  ? 631 LEU A O   1 
ATOM   4153  C CB  . LEU A 1 631 ? 148.832 133.853 152.353 1.00 23.19  ? 631 LEU A CB  1 
ATOM   4154  C CG  . LEU A 1 631 ? 148.517 135.093 153.215 1.00 27.07  ? 631 LEU A CG  1 
ATOM   4155  C CD1 . LEU A 1 631 ? 149.799 135.873 153.478 1.00 25.75  ? 631 LEU A CD1 1 
ATOM   4156  C CD2 . LEU A 1 631 ? 147.507 136.026 152.553 1.00 22.48  ? 631 LEU A CD2 1 
ATOM   4157  N N   . LEU A 1 632 ? 148.674 130.729 151.467 1.00 18.97  ? 632 LEU A N   1 
ATOM   4158  C CA  . LEU A 1 632 ? 148.872 129.591 150.562 1.00 11.83  ? 632 LEU A CA  1 
ATOM   4159  C C   . LEU A 1 632 ? 147.572 128.855 150.244 1.00 8.93   ? 632 LEU A C   1 
ATOM   4160  O O   . LEU A 1 632 ? 147.310 128.518 149.098 1.00 29.87  ? 632 LEU A O   1 
ATOM   4161  C CB  . LEU A 1 632 ? 149.872 128.606 151.183 1.00 23.81  ? 632 LEU A CB  1 
ATOM   4162  C CG  . LEU A 1 632 ? 151.315 129.119 151.240 1.00 22.99  ? 632 LEU A CG  1 
ATOM   4163  C CD1 . LEU A 1 632 ? 152.172 128.179 152.068 1.00 20.41  ? 632 LEU A CD1 1 
ATOM   4164  C CD2 . LEU A 1 632 ? 151.930 129.203 149.856 1.00 18.01  ? 632 LEU A CD2 1 
ATOM   4165  N N   . THR A 1 633 ? 146.726 128.627 151.244 1.00 27.45  ? 633 THR A N   1 
ATOM   4166  C CA  . THR A 1 633 ? 145.441 127.940 151.080 1.00 18.98  ? 633 THR A CA  1 
ATOM   4167  C C   . THR A 1 633 ? 144.466 128.766 150.251 1.00 14.74  ? 633 THR A C   1 
ATOM   4168  O O   . THR A 1 633 ? 143.761 128.216 149.416 1.00 28.45  ? 633 THR A O   1 
ATOM   4169  C CB  . THR A 1 633 ? 144.854 127.608 152.454 1.00 17.84  ? 633 THR A CB  1 
ATOM   4170  O OG1 . THR A 1 633 ? 145.749 126.758 153.106 1.00 23.68  ? 633 THR A OG1 1 
ATOM   4171  C CG2 . THR A 1 633 ? 143.512 126.893 152.418 1.00 24.95  ? 633 THR A CG2 1 
ATOM   4172  N N   . TYR A 1 634 ? 144.446 130.085 150.412 1.00 20.58  ? 634 TYR A N   1 
ATOM   4173  C CA  . TYR A 1 634 ? 143.590 130.969 149.627 1.00 15.36  ? 634 TYR A CA  1 
ATOM   4174  C C   . TYR A 1 634 ? 144.086 131.101 148.180 1.00 20.26  ? 634 TYR A C   1 
ATOM   4175  O O   . TYR A 1 634 ? 143.261 131.104 147.270 1.00 29.47  ? 634 TYR A O   1 
ATOM   4176  C CB  . TYR A 1 634 ? 143.409 132.330 150.303 1.00 22.68  ? 634 TYR A CB  1 
ATOM   4177  C CG  . TYR A 1 634 ? 142.395 132.293 151.419 1.00 33.91  ? 634 TYR A CG  1 
ATOM   4178  C CD1 . TYR A 1 634 ? 142.210 131.137 152.163 1.00 36.83  ? 634 TYR A CD1 1 
ATOM   4179  C CD2 . TYR A 1 634 ? 141.611 133.390 151.731 1.00 30.24  ? 634 TYR A CD2 1 
ATOM   4180  C CE1 . TYR A 1 634 ? 141.284 131.068 153.187 1.00 25.80  ? 634 TYR A CE1 1 
ATOM   4181  C CE2 . TYR A 1 634 ? 140.675 133.340 152.752 1.00 26.82  ? 634 TYR A CE2 1 
ATOM   4182  C CZ  . TYR A 1 634 ? 140.512 132.174 153.481 1.00 30.48  ? 634 TYR A CZ  1 
ATOM   4183  O OH  . TYR A 1 634 ? 139.600 132.101 154.491 1.00 37.21  ? 634 TYR A OH  1 
ATOM   4184  N N   . VAL A 1 635 ? 145.403 131.116 147.951 1.00 24.04  ? 635 VAL A N   1 
ATOM   4185  C CA  . VAL A 1 635 ? 146.004 130.981 146.621 1.00 18.90  ? 635 VAL A CA  1 
ATOM   4186  C C   . VAL A 1 635 ? 145.621 129.641 145.990 1.00 17.54  ? 635 VAL A C   1 
ATOM   4187  O O   . VAL A 1 635 ? 145.185 129.623 144.847 1.00 27.82  ? 635 VAL A O   1 
ATOM   4188  C CB  . VAL A 1 635 ? 147.534 131.145 146.682 1.00 24.50  ? 635 VAL A CB  1 
ATOM   4189  C CG1 . VAL A 1 635 ? 148.235 130.818 145.359 1.00 24.17  ? 635 VAL A CG1 1 
ATOM   4190  C CG2 . VAL A 1 635 ? 147.947 132.570 147.025 1.00 24.95  ? 635 VAL A CG2 1 
ATOM   4191  N N   . LEU A 1 636 ? 145.728 128.519 146.706 1.00 15.80  ? 636 LEU A N   1 
ATOM   4192  C CA  . LEU A 1 636 ? 145.333 127.200 146.212 1.00 12.37  ? 636 LEU A CA  1 
ATOM   4193  C C   . LEU A 1 636 ? 143.833 127.096 145.903 1.00 18.40  ? 636 LEU A C   1 
ATOM   4194  O O   . LEU A 1 636 ? 143.477 126.605 144.841 1.00 31.14  ? 636 LEU A O   1 
ATOM   4195  C CB  . LEU A 1 636 ? 145.781 126.143 147.236 1.00 23.96  ? 636 LEU A CB  1 
ATOM   4196  C CG  . LEU A 1 636 ? 145.313 124.707 146.930 1.00 28.74  ? 636 LEU A CG  1 
ATOM   4197  C CD1 . LEU A 1 636 ? 146.000 124.130 145.702 1.00 26.57  ? 636 LEU A CD1 1 
ATOM   4198  C CD2 . LEU A 1 636 ? 145.604 123.800 148.117 1.00 30.03  ? 636 LEU A CD2 1 
ATOM   4199  N N   . LEU A 1 637 ? 142.951 127.560 146.790 1.00 18.86  ? 637 LEU A N   1 
ATOM   4200  C CA  . LEU A 1 637 ? 141.504 127.528 146.580 1.00 14.46  ? 637 LEU A CA  1 
ATOM   4201  C C   . LEU A 1 637 ? 141.087 128.417 145.409 1.00 20.10  ? 637 LEU A C   1 
ATOM   4202  O O   . LEU A 1 637 ? 140.299 128.003 144.572 1.00 23.17  ? 637 LEU A O   1 
ATOM   4203  C CB  . LEU A 1 637 ? 140.777 127.944 147.869 1.00 24.62  ? 637 LEU A CB  1 
ATOM   4204  C CG  . LEU A 1 637 ? 140.819 126.883 148.987 1.00 28.24  ? 637 LEU A CG  1 
ATOM   4205  C CD1 . LEU A 1 637 ? 140.337 127.495 150.302 1.00 25.87  ? 637 LEU A CD1 1 
ATOM   4206  C CD2 . LEU A 1 637 ? 139.931 125.686 148.671 1.00 23.64  ? 637 LEU A CD2 1 
ATOM   4207  N N   . LEU A 1 638 ? 141.655 129.610 145.295 1.00 22.53  ? 638 LEU A N   1 
ATOM   4208  C CA  . LEU A 1 638 ? 141.399 130.519 144.189 1.00 18.92  ? 638 LEU A CA  1 
ATOM   4209  C C   . LEU A 1 638 ? 141.885 129.959 142.848 1.00 15.03  ? 638 LEU A C   1 
ATOM   4210  O O   . LEU A 1 638 ? 141.155 129.986 141.869 1.00 29.96  ? 638 LEU A O   1 
ATOM   4211  C CB  . LEU A 1 638 ? 142.049 131.856 144.560 1.00 25.88  ? 638 LEU A CB  1 
ATOM   4212  C CG  . LEU A 1 638 ? 141.921 132.976 143.531 1.00 21.05  ? 638 LEU A CG  1 
ATOM   4213  C CD1 . LEU A 1 638 ? 140.483 133.223 143.112 1.00 22.24  ? 638 LEU A CD1 1 
ATOM   4214  C CD2 . LEU A 1 638 ? 142.474 134.249 144.154 1.00 17.90  ? 638 LEU A CD2 1 
ATOM   4215  N N   . ASN A 1 639 ? 143.079 129.373 142.810 1.00 24.10  ? 639 ASN A N   1 
ATOM   4216  C CA  . ASN A 1 639 ? 143.581 128.636 141.654 1.00 18.52  ? 639 ASN A CA  1 
ATOM   4217  C C   . ASN A 1 639 ? 142.684 127.442 141.281 1.00 18.20  ? 639 ASN A C   1 
ATOM   4218  O O   . ASN A 1 639 ? 142.348 127.276 140.118 1.00 23.90  ? 639 ASN A O   1 
ATOM   4219  C CB  . ASN A 1 639 ? 145.005 128.166 141.953 1.00 19.15  ? 639 ASN A CB  1 
ATOM   4220  C CG  . ASN A 1 639 ? 146.071 129.161 141.545 1.00 24.18  ? 639 ASN A CG  1 
ATOM   4221  O OD1 . ASN A 1 639 ? 146.333 129.399 140.384 1.00 31.22  ? 639 ASN A OD1 1 
ATOM   4222  N ND2 . ASN A 1 639 ? 146.731 129.789 142.477 1.00 30.95  ? 639 ASN A ND2 1 
ATOM   4223  N N   . MET A 1 640 ? 142.252 126.637 142.247 1.00 25.09  ? 640 MET A N   1 
ATOM   4224  C CA  . MET A 1 640 ? 141.338 125.517 142.041 1.00 18.01  ? 640 MET A CA  1 
ATOM   4225  C C   . MET A 1 640 ? 139.985 125.955 141.471 1.00 21.18  ? 640 MET A C   1 
ATOM   4226  O O   . MET A 1 640 ? 139.511 125.364 140.508 1.00 31.21  ? 640 MET A O   1 
ATOM   4227  C CB  . MET A 1 640 ? 141.202 124.764 143.372 1.00 24.23  ? 640 MET A CB  1 
ATOM   4228  C CG  . MET A 1 640 ? 140.300 123.529 143.328 1.00 26.88  ? 640 MET A CG  1 
ATOM   4229  S SD  . MET A 1 640 ? 138.543 123.756 143.657 1.00 40.73  ? 640 MET A SD  1 
ATOM   4230  C CE  . MET A 1 640 ? 138.558 124.223 145.399 1.00 27.25  ? 640 MET A CE  1 
ATOM   4231  N N   . LEU A 1 641 ? 139.382 127.020 142.001 1.00 24.58  ? 641 LEU A N   1 
ATOM   4232  C CA  . LEU A 1 641 ? 138.108 127.550 141.510 1.00 21.40  ? 641 LEU A CA  1 
ATOM   4233  C C   . LEU A 1 641 ? 138.219 128.110 140.091 1.00 19.67  ? 641 LEU A C   1 
ATOM   4234  O O   . LEU A 1 641 ? 137.385 127.808 139.247 1.00 26.59  ? 641 LEU A O   1 
ATOM   4235  C CB  . LEU A 1 641 ? 137.582 128.617 142.484 1.00 26.34  ? 641 LEU A CB  1 
ATOM   4236  C CG  . LEU A 1 641 ? 137.135 128.056 143.844 1.00 30.82  ? 641 LEU A CG  1 
ATOM   4237  C CD1 . LEU A 1 641 ? 136.869 129.194 144.820 1.00 27.86  ? 641 LEU A CD1 1 
ATOM   4238  C CD2 . LEU A 1 641 ? 135.878 127.210 143.730 1.00 24.89  ? 641 LEU A CD2 1 
ATOM   4239  N N   . ILE A 1 642 ? 139.253 128.894 139.805 1.00 24.89  ? 642 ILE A N   1 
ATOM   4240  C CA  . ILE A 1 642 ? 139.501 129.425 138.465 1.00 19.62  ? 642 ILE A CA  1 
ATOM   4241  C C   . ILE A 1 642 ? 139.800 128.294 137.467 1.00 19.82  ? 642 ILE A C   1 
ATOM   4242  O O   . ILE A 1 642 ? 139.240 128.290 136.374 1.00 32.42  ? 642 ILE A O   1 
ATOM   4243  C CB  . ILE A 1 642 ? 140.618 130.486 138.543 1.00 27.53  ? 642 ILE A CB  1 
ATOM   4244  C CG1 . ILE A 1 642 ? 140.164 131.789 139.241 1.00 21.68  ? 642 ILE A CG1 1 
ATOM   4245  C CG2 . ILE A 1 642 ? 141.179 130.807 137.162 1.00 26.55  ? 642 ILE A CG2 1 
ATOM   4246  C CD1 . ILE A 1 642 ? 139.117 132.628 138.506 1.00 23.53  ? 642 ILE A CD1 1 
ATOM   4247  N N   . ALA A 1 643 ? 140.593 127.287 137.834 1.00 23.64  ? 643 ALA A N   1 
ATOM   4248  C CA  . ALA A 1 643 ? 140.826 126.116 136.997 1.00 12.63  ? 643 ALA A CA  1 
ATOM   4249  C C   . ALA A 1 643 ? 139.553 125.287 136.741 1.00 18.95  ? 643 ALA A C   1 
ATOM   4250  O O   . ALA A 1 643 ? 139.383 124.782 135.637 1.00 35.66  ? 643 ALA A O   1 
ATOM   4251  C CB  . ALA A 1 643 ? 141.936 125.270 137.626 1.00 21.55  ? 643 ALA A CB  1 
ATOM   4252  N N   . LEU A 1 644 ? 138.621 125.175 137.696 1.00 30.99  ? 644 LEU A N   1 
ATOM   4253  C CA  . LEU A 1 644 ? 137.302 124.586 137.438 1.00 24.98  ? 644 LEU A CA  1 
ATOM   4254  C C   . LEU A 1 644 ? 136.476 125.414 136.461 1.00 24.51  ? 644 LEU A C   1 
ATOM   4255  O O   . LEU A 1 644 ? 135.876 124.837 135.563 1.00 34.03  ? 644 LEU A O   1 
ATOM   4256  C CB  . LEU A 1 644 ? 136.504 124.408 138.735 1.00 26.64  ? 644 LEU A CB  1 
ATOM   4257  C CG  . LEU A 1 644 ? 136.960 123.249 139.622 1.00 31.14  ? 644 LEU A CG  1 
ATOM   4258  C CD1 . LEU A 1 644 ? 136.126 123.274 140.894 1.00 27.84  ? 644 LEU A CD1 1 
ATOM   4259  C CD2 . LEU A 1 644 ? 136.760 121.890 138.955 1.00 34.04  ? 644 LEU A CD2 1 
ATOM   4260  N N   . MET A 1 645 ? 136.435 126.742 136.578 1.00 32.70  ? 645 MET A N   1 
ATOM   4261  C CA  . MET A 1 645 ? 135.718 127.593 135.623 1.00 28.86  ? 645 MET A CA  1 
ATOM   4262  C C   . MET A 1 645 ? 136.262 127.448 134.198 1.00 31.61  ? 645 MET A C   1 
ATOM   4263  O O   . MET A 1 645 ? 135.480 127.216 133.283 1.00 37.35  ? 645 MET A O   1 
ATOM   4264  C CB  . MET A 1 645 ? 135.758 129.056 136.055 1.00 29.17  ? 645 MET A CB  1 
ATOM   4265  C CG  . MET A 1 645 ? 134.950 129.297 137.322 1.00 32.65  ? 645 MET A CG  1 
ATOM   4266  S SD  . MET A 1 645 ? 135.150 130.959 137.997 1.00 52.21  ? 645 MET A SD  1 
ATOM   4267  C CE  . MET A 1 645 ? 134.646 130.616 139.700 1.00 37.43  ? 645 MET A CE  1 
ATOM   4268  N N   . SER A 1 646 ? 137.585 127.487 134.002 1.00 33.02  ? 646 SER A N   1 
ATOM   4269  C CA  . SER A 1 646 ? 138.225 127.281 132.697 1.00 32.03  ? 646 SER A CA  1 
ATOM   4270  C C   . SER A 1 646 ? 137.883 125.929 132.059 1.00 37.47  ? 646 SER A C   1 
ATOM   4271  O O   . SER A 1 646 ? 137.839 125.818 130.840 1.00 45.37  ? 646 SER A O   1 
ATOM   4272  C CB  . SER A 1 646 ? 139.750 127.365 132.816 1.00 27.85  ? 646 SER A CB  1 
ATOM   4273  O OG  . SER A 1 646 ? 140.172 128.590 133.374 1.00 36.36  ? 646 SER A OG  1 
ATOM   4274  N N   . GLU A 1 647 ? 137.644 124.885 132.846 1.00 36.15  ? 647 GLU A N   1 
ATOM   4275  C CA  . GLU A 1 647 ? 137.293 123.559 132.332 1.00 36.22  ? 647 GLU A CA  1 
ATOM   4276  C C   . GLU A 1 647 ? 135.783 123.374 132.088 1.00 39.21  ? 647 GLU A C   1 
ATOM   4277  O O   . GLU A 1 647 ? 135.380 122.660 131.174 1.00 44.20  ? 647 GLU A O   1 
ATOM   4278  C CB  . GLU A 1 647 ? 137.836 122.512 133.313 1.00 35.63  ? 647 GLU A CB  1 
ATOM   4279  C CG  . GLU A 1 647 ? 137.605 121.049 132.907 1.00 45.33  ? 647 GLU A CG  1 
ATOM   4280  C CD  . GLU A 1 647 ? 138.515 120.544 131.772 1.00 50.47  ? 647 GLU A CD  1 
ATOM   4281  O OE1 . GLU A 1 647 ? 138.787 121.287 130.803 1.00 50.08  ? 647 GLU A OE1 1 
ATOM   4282  O OE2 . GLU A 1 647 ? 138.964 119.381 131.858 1.00 47.95  ? 647 GLU A OE2 1 
ATOM   4283  N N   . THR A 1 648 ? 134.932 124.005 132.898 1.00 35.61  ? 648 THR A N   1 
ATOM   4284  C CA  . THR A 1 648 ? 133.494 123.697 132.959 1.00 34.31  ? 648 THR A CA  1 
ATOM   4285  C C   . THR A 1 648 ? 132.575 124.731 132.305 1.00 35.08  ? 648 THR A C   1 
ATOM   4286  O O   . THR A 1 648 ? 131.458 124.375 131.935 1.00 40.24  ? 648 THR A O   1 
ATOM   4287  C CB  . THR A 1 648 ? 133.044 123.465 134.411 1.00 36.55  ? 648 THR A CB  1 
ATOM   4288  O OG1 . THR A 1 648 ? 133.292 124.592 135.203 1.00 40.46  ? 648 THR A OG1 1 
ATOM   4289  C CG2 . THR A 1 648 ? 133.696 122.259 135.084 1.00 28.28  ? 648 THR A CG2 1 
ATOM   4290  N N   . VAL A 1 649 ? 133.001 125.985 132.131 1.00 36.00  ? 649 VAL A N   1 
ATOM   4291  C CA  . VAL A 1 649 ? 132.160 127.105 131.657 1.00 38.52  ? 649 VAL A CA  1 
ATOM   4292  C C   . VAL A 1 649 ? 132.571 127.514 130.232 1.00 38.34  ? 649 VAL A C   1 
ATOM   4293  O O   . VAL A 1 649 ? 133.052 128.612 129.988 1.00 40.52  ? 649 VAL A O   1 
ATOM   4294  C CB  . VAL A 1 649 ? 132.143 128.275 132.674 1.00 39.25  ? 649 VAL A CB  1 
ATOM   4295  C CG1 . VAL A 1 649 ? 131.092 129.342 132.331 1.00 39.42  ? 649 VAL A CG1 1 
ATOM   4296  C CG2 . VAL A 1 649 ? 131.805 127.803 134.096 1.00 31.13  ? 649 VAL A CG2 1 
ATOM   4297  N N   . ASN A 1 650 ? 132.426 126.585 129.284 1.00 42.21  ? 650 ASN A N   1 
ATOM   4298  C CA  . ASN A 1 650 ? 132.943 126.672 127.910 1.00 39.29  ? 650 ASN A CA  1 
ATOM   4299  C C   . ASN A 1 650 ? 131.874 126.749 126.800 1.00 41.39  ? 650 ASN A C   1 
ATOM   4300  O O   . ASN A 1 650 ? 132.190 126.558 125.631 1.00 43.19  ? 650 ASN A O   1 
ATOM   4301  C CB  . ASN A 1 650 ? 133.956 125.530 127.693 1.00 44.19  ? 650 ASN A CB  1 
ATOM   4302  C CG  . ASN A 1 650 ? 135.278 125.797 128.393 1.00 48.36  ? 650 ASN A CG  1 
ATOM   4303  O OD1 . ASN A 1 650 ? 135.867 126.857 128.259 1.00 47.24  ? 650 ASN A OD1 1 
ATOM   4304  N ND2 . ASN A 1 650 ? 135.801 124.864 129.139 1.00 44.72  ? 650 ASN A ND2 1 
ATOM   4305  N N   . HIS A 1 651 ? 130.615 127.027 127.140 1.00 43.37  ? 651 HIS A N   1 
ATOM   4306  C CA  . HIS A 1 651 ? 129.484 127.208 126.202 1.00 39.98  ? 651 HIS A CA  1 
ATOM   4307  C C   . HIS A 1 651 ? 129.160 126.009 125.300 1.00 42.66  ? 651 HIS A C   1 
ATOM   4308  O O   . HIS A 1 651 ? 128.474 126.151 124.287 1.00 50.25  ? 651 HIS A O   1 
ATOM   4309  C CB  . HIS A 1 651 ? 129.736 128.462 125.347 1.00 42.40  ? 651 HIS A CB  1 
ATOM   4310  C CG  . HIS A 1 651 ? 130.135 129.655 126.150 1.00 41.23  ? 651 HIS A CG  1 
ATOM   4311  N ND1 . HIS A 1 651 ? 129.213 130.568 126.625 1.00 44.34  ? 651 HIS A ND1 1 
ATOM   4312  C CD2 . HIS A 1 651 ? 131.345 130.083 126.570 1.00 44.88  ? 651 HIS A CD2 1 
ATOM   4313  C CE1 . HIS A 1 651 ? 129.839 131.510 127.300 1.00 43.64  ? 651 HIS A CE1 1 
ATOM   4314  N NE2 . HIS A 1 651 ? 131.149 131.236 127.281 1.00 42.42  ? 651 HIS A NE2 1 
ATOM   4315  N N   . VAL A 1 652 ? 129.621 124.813 125.664 1.00 47.14  ? 652 VAL A N   1 
ATOM   4316  C CA  . VAL A 1 652 ? 129.201 123.560 125.028 1.00 44.64  ? 652 VAL A CA  1 
ATOM   4317  C C   . VAL A 1 652 ? 127.702 123.336 125.236 1.00 46.23  ? 652 VAL A C   1 
ATOM   4318  O O   . VAL A 1 652 ? 127.137 123.762 126.246 1.00 45.90  ? 652 VAL A O   1 
ATOM   4319  C CB  . VAL A 1 652 ? 130.026 122.361 125.522 1.00 45.38  ? 652 VAL A CB  1 
ATOM   4320  C CG1 . VAL A 1 652 ? 131.510 122.545 125.172 1.00 43.86  ? 652 VAL A CG1 1 
ATOM   4321  C CG2 . VAL A 1 652 ? 129.903 122.105 127.028 1.00 47.71  ? 652 VAL A CG2 1 
ATOM   4322  N N   . ALA A 1 653 ? 127.042 122.686 124.283 1.00 51.36  ? 653 ALA A N   1 
ATOM   4323  C CA  . ALA A 1 653 ? 125.606 122.429 124.357 1.00 51.38  ? 653 ALA A CA  1 
ATOM   4324  C C   . ALA A 1 653 ? 125.233 121.601 125.603 1.00 53.52  ? 653 ALA A C   1 
ATOM   4325  O O   . ALA A 1 653 ? 125.935 120.663 125.986 1.00 52.14  ? 653 ALA A O   1 
ATOM   4326  C CB  . ALA A 1 653 ? 125.159 121.756 123.059 1.00 49.84  ? 653 ALA A CB  1 
ATOM   4327  N N   . ASP A 1 654 ? 124.115 121.948 126.236 1.00 52.55  ? 654 ASP A N   1 
ATOM   4328  C CA  . ASP A 1 654 ? 123.621 121.295 127.449 1.00 50.58  ? 654 ASP A CA  1 
ATOM   4329  C C   . ASP A 1 654 ? 123.021 119.907 127.154 1.00 51.43  ? 654 ASP A C   1 
ATOM   4330  O O   . ASP A 1 654 ? 121.826 119.752 126.912 1.00 51.33  ? 654 ASP A O   1 
ATOM   4331  C CB  . ASP A 1 654 ? 122.611 122.237 128.123 1.00 52.20  ? 654 ASP A CB  1 
ATOM   4332  C CG  . ASP A 1 654 ? 122.030 121.650 129.408 1.00 57.76  ? 654 ASP A CG  1 
ATOM   4333  O OD1 . ASP A 1 654 ? 122.639 120.720 129.989 1.00 58.12  ? 654 ASP A OD1 1 
ATOM   4334  O OD2 . ASP A 1 654 ? 120.947 122.098 129.831 1.00 57.40  ? 654 ASP A OD2 1 
ATOM   4335  N N   . ASN A 1 655 ? 123.859 118.874 127.180 1.00 45.82  ? 655 ASN A N   1 
ATOM   4336  C CA  . ASN A 1 655 ? 123.496 117.473 126.943 1.00 42.19  ? 655 ASN A CA  1 
ATOM   4337  C C   . ASN A 1 655 ? 122.813 116.781 128.143 1.00 40.98  ? 655 ASN A C   1 
ATOM   4338  O O   . ASN A 1 655 ? 122.660 115.559 128.159 1.00 44.53  ? 655 ASN A O   1 
ATOM   4339  C CB  . ASN A 1 655 ? 124.738 116.716 126.444 1.00 40.98  ? 655 ASN A CB  1 
ATOM   4340  C CG  . ASN A 1 655 ? 125.881 116.640 127.440 1.00 45.38  ? 655 ASN A CG  1 
ATOM   4341  O OD1 . ASN A 1 655 ? 125.793 117.061 128.580 1.00 50.39  ? 655 ASN A OD1 1 
ATOM   4342  N ND2 . ASN A 1 655 ? 127.016 116.128 127.032 1.00 44.54  ? 655 ASN A ND2 1 
ATOM   4343  N N   . SER A 1 656 ? 122.382 117.528 129.161 1.00 42.05  ? 656 SER A N   1 
ATOM   4344  C CA  . SER A 1 656 ? 121.804 116.958 130.379 1.00 38.78  ? 656 SER A CA  1 
ATOM   4345  C C   . SER A 1 656 ? 120.459 116.262 130.152 1.00 37.66  ? 656 SER A C   1 
ATOM   4346  O O   . SER A 1 656 ? 120.205 115.238 130.779 1.00 41.50  ? 656 SER A O   1 
ATOM   4347  C CB  . SER A 1 656 ? 121.684 118.038 131.454 1.00 37.31  ? 656 SER A CB  1 
ATOM   4348  O OG  . SER A 1 656 ? 120.886 119.095 130.986 1.00 45.08  ? 656 SER A OG  1 
ATOM   4349  N N   . TRP A 1 657 ? 119.634 116.730 129.205 1.00 28.79  ? 657 TRP A N   1 
ATOM   4350  C CA  . TRP A 1 657 ? 118.399 116.042 128.795 1.00 25.07  ? 657 TRP A CA  1 
ATOM   4351  C C   . TRP A 1 657 ? 118.671 114.643 128.228 1.00 28.34  ? 657 TRP A C   1 
ATOM   4352  O O   . TRP A 1 657 ? 118.026 113.679 128.627 1.00 34.27  ? 657 TRP A O   1 
ATOM   4353  C CB  . TRP A 1 657 ? 117.623 116.911 127.801 1.00 21.15  ? 657 TRP A CB  1 
ATOM   4354  C CG  . TRP A 1 657 ? 116.390 116.278 127.228 1.00 26.85  ? 657 TRP A CG  1 
ATOM   4355  C CD1 . TRP A 1 657 ? 115.142 116.366 127.746 1.00 27.87  ? 657 TRP A CD1 1 
ATOM   4356  C CD2 . TRP A 1 657 ? 116.254 115.462 126.031 1.00 30.03  ? 657 TRP A CD2 1 
ATOM   4357  N NE1 . TRP A 1 657 ? 114.264 115.628 126.983 1.00 29.05  ? 657 TRP A NE1 1 
ATOM   4358  C CE2 . TRP A 1 657 ? 114.897 115.041 125.910 1.00 31.31  ? 657 TRP A CE2 1 
ATOM   4359  C CE3 . TRP A 1 657 ? 117.133 115.069 124.995 1.00 24.84  ? 657 TRP A CE3 1 
ATOM   4360  C CZ2 . TRP A 1 657 ? 114.443 114.249 124.852 1.00 29.13  ? 657 TRP A CZ2 1 
ATOM   4361  C CZ3 . TRP A 1 657 ? 116.680 114.297 123.918 1.00 28.94  ? 657 TRP A CZ3 1 
ATOM   4362  C CH2 . TRP A 1 657 ? 115.345 113.864 123.848 1.00 31.67  ? 657 TRP A CH2 1 
ATOM   4363  N N   . SER A 1 658 ? 119.675 114.504 127.365 1.00 33.66  ? 658 SER A N   1 
ATOM   4364  C CA  . SER A 1 658 ? 120.085 113.225 126.789 1.00 21.31  ? 658 SER A CA  1 
ATOM   4365  C C   . SER A 1 658 ? 120.642 112.269 127.841 1.00 25.95  ? 658 SER A C   1 
ATOM   4366  O O   . SER A 1 658 ? 120.312 111.086 127.853 1.00 31.89  ? 658 SER A O   1 
ATOM   4367  C CB  . SER A 1 658 ? 121.163 113.446 125.723 1.00 27.71  ? 658 SER A CB  1 
ATOM   4368  O OG  . SER A 1 658 ? 120.742 114.422 124.792 1.00 41.52  ? 658 SER A OG  1 
ATOM   4369  N N   . ILE A 1 659 ? 121.476 112.762 128.760 1.00 29.32  ? 659 ILE A N   1 
ATOM   4370  C CA  . ILE A 1 659 ? 122.042 111.944 129.842 1.00 31.60  ? 659 ILE A CA  1 
ATOM   4371  C C   . ILE A 1 659 ? 120.949 111.485 130.819 1.00 21.00  ? 659 ILE A C   1 
ATOM   4372  O O   . ILE A 1 659 ? 120.969 110.346 131.271 1.00 23.27  ? 659 ILE A O   1 
ATOM   4373  C CB  . ILE A 1 659 ? 123.191 112.706 130.528 1.00 28.00  ? 659 ILE A CB  1 
ATOM   4374  C CG1 . ILE A 1 659 ? 124.393 112.854 129.581 1.00 26.93  ? 659 ILE A CG1 1 
ATOM   4375  C CG2 . ILE A 1 659 ? 123.633 112.020 131.832 1.00 27.78  ? 659 ILE A CG2 1 
ATOM   4376  C CD1 . ILE A 1 659 ? 125.424 113.876 130.047 1.00 27.73  ? 659 ILE A CD1 1 
ATOM   4377  N N   . TRP A 1 660 ? 119.937 112.303 131.086 1.00 17.28  ? 660 TRP A N   1 
ATOM   4378  C CA  . TRP A 1 660 ? 118.743 111.884 131.807 1.00 10.55  ? 660 TRP A CA  1 
ATOM   4379  C C   . TRP A 1 660 ? 117.889 110.856 131.044 1.00 22.08  ? 660 TRP A C   1 
ATOM   4380  O O   . TRP A 1 660 ? 117.441 109.876 131.635 1.00 29.40  ? 660 TRP A O   1 
ATOM   4381  C CB  . TRP A 1 660 ? 117.948 113.126 132.186 1.00 17.93  ? 660 TRP A CB  1 
ATOM   4382  C CG  . TRP A 1 660 ? 116.583 112.845 132.709 1.00 26.63  ? 660 TRP A CG  1 
ATOM   4383  C CD1 . TRP A 1 660 ? 116.293 112.223 133.870 1.00 15.35  ? 660 TRP A CD1 1 
ATOM   4384  C CD2 . TRP A 1 660 ? 115.313 113.066 132.039 1.00 23.18  ? 660 TRP A CD2 1 
ATOM   4385  N NE1 . TRP A 1 660 ? 114.926 112.112 133.995 1.00 16.84  ? 660 TRP A NE1 1 
ATOM   4386  C CE2 . TRP A 1 660 ? 114.274 112.637 132.906 1.00 21.55  ? 660 TRP A CE2 1 
ATOM   4387  C CE3 . TRP A 1 660 ? 114.940 113.593 130.786 1.00 25.93  ? 660 TRP A CE3 1 
ATOM   4388  C CZ2 . TRP A 1 660 ? 112.921 112.781 132.573 1.00 19.79  ? 660 TRP A CZ2 1 
ATOM   4389  C CZ3 . TRP A 1 660 ? 113.590 113.710 130.428 1.00 28.74  ? 660 TRP A CZ3 1 
ATOM   4390  C CH2 . TRP A 1 660 ? 112.582 113.311 131.320 1.00 28.98  ? 660 TRP A CH2 1 
ATOM   4391  N N   . LYS A 1 661 ? 117.711 110.983 129.723 1.00 26.49  ? 661 LYS A N   1 
ATOM   4392  C CA  . LYS A 1 661 ? 117.059 109.940 128.910 1.00 12.24  ? 661 LYS A CA  1 
ATOM   4393  C C   . LYS A 1 661 ? 117.820 108.614 128.959 1.00 13.22  ? 661 LYS A C   1 
ATOM   4394  O O   . LYS A 1 661 ? 117.188 107.564 128.991 1.00 23.78  ? 661 LYS A O   1 
ATOM   4395  C CB  . LYS A 1 661 ? 116.879 110.404 127.456 1.00 18.81  ? 661 LYS A CB  1 
ATOM   4396  C CG  . LYS A 1 661 ? 115.800 111.466 127.232 1.00 13.68  ? 661 LYS A CG  1 
ATOM   4397  C CD  . LYS A 1 661 ? 114.401 111.040 127.688 1.00 16.52  ? 661 LYS A CD  1 
ATOM   4398  C CE  . LYS A 1 661 ? 113.370 112.002 127.097 1.00 27.22  ? 661 LYS A CE  1 
ATOM   4399  N NZ  . LYS A 1 661 ? 111.998 111.760 127.611 1.00 30.44  ? 661 LYS A NZ  1 
ATOM   4400  N N   . LEU A 1 662 ? 119.147 108.629 129.056 1.00 16.36  ? 662 LEU A N   1 
ATOM   4401  C CA  . LEU A 1 662 ? 119.953 107.435 129.313 1.00 12.57  ? 662 LEU A CA  1 
ATOM   4402  C C   . LEU A 1 662 ? 119.758 106.866 130.730 1.00 15.77  ? 662 LEU A C   1 
ATOM   4403  O O   . LEU A 1 662 ? 119.649 105.656 130.879 1.00 28.76  ? 662 LEU A O   1 
ATOM   4404  C CB  . LEU A 1 662 ? 121.419 107.748 128.984 1.00 16.98  ? 662 LEU A CB  1 
ATOM   4405  C CG  . LEU A 1 662 ? 122.405 106.593 129.219 1.00 20.55  ? 662 LEU A CG  1 
ATOM   4406  C CD1 . LEU A 1 662 ? 122.167 105.407 128.296 1.00 16.72  ? 662 LEU A CD1 1 
ATOM   4407  C CD2 . LEU A 1 662 ? 123.812 107.097 128.983 1.00 14.86  ? 662 LEU A CD2 1 
ATOM   4408  N N   . GLN A 1 663 ? 119.632 107.691 131.768 1.00 25.38  ? 663 GLN A N   1 
ATOM   4409  C CA  . GLN A 1 663 ? 119.278 107.221 133.115 1.00 9.62   ? 663 GLN A CA  1 
ATOM   4410  C C   . GLN A 1 663 ? 117.913 106.536 133.155 1.00 15.61  ? 663 GLN A C   1 
ATOM   4411  O O   . GLN A 1 663 ? 117.782 105.461 133.742 1.00 25.43  ? 663 GLN A O   1 
ATOM   4412  C CB  . GLN A 1 663 ? 119.269 108.381 134.109 1.00 15.15  ? 663 GLN A CB  1 
ATOM   4413  C CG  . GLN A 1 663 ? 120.658 108.925 134.419 1.00 12.53  ? 663 GLN A CG  1 
ATOM   4414  C CD  . GLN A 1 663 ? 120.591 110.114 135.360 1.00 16.31  ? 663 GLN A CD  1 
ATOM   4415  O OE1 . GLN A 1 663 ? 119.535 110.636 135.668 1.00 30.67  ? 663 GLN A OE1 1 
ATOM   4416  N NE2 . GLN A 1 663 ? 121.713 110.563 135.857 1.00 24.77  ? 663 GLN A NE2 1 
ATOM   4417  N N   . LYS A 1 664 ? 116.908 107.123 132.495 1.00 24.83  ? 664 LYS A N   1 
ATOM   4418  C CA  . LYS A 1 664 ? 115.597 106.499 132.289 1.00 4.45   ? 664 LYS A CA  1 
ATOM   4419  C C   . LYS A 1 664 ? 115.691 105.189 131.519 1.00 17.62  ? 664 LYS A C   1 
ATOM   4420  O O   . LYS A 1 664 ? 115.063 104.231 131.935 1.00 34.20  ? 664 LYS A O   1 
ATOM   4421  C CB  . LYS A 1 664 ? 114.637 107.466 131.596 1.00 15.21  ? 664 LYS A CB  1 
ATOM   4422  C CG  . LYS A 1 664 ? 114.056 108.484 132.575 1.00 15.92  ? 664 LYS A CG  1 
ATOM   4423  C CD  . LYS A 1 664 ? 112.845 109.192 131.965 1.00 17.77  ? 664 LYS A CD  1 
ATOM   4424  C CE  . LYS A 1 664 ? 111.983 109.730 133.111 1.00 33.85  ? 664 LYS A CE  1 
ATOM   4425  N NZ  . LYS A 1 664 ? 110.679 110.262 132.625 1.00 37.07  ? 664 LYS A NZ  1 
ATOM   4426  N N   . ALA A 1 665 ? 116.508 105.107 130.471 1.00 20.17  ? 665 ALA A N   1 
ATOM   4427  C CA  . ALA A 1 665 ? 116.738 103.881 129.715 1.00 7.71   ? 665 ALA A CA  1 
ATOM   4428  C C   . ALA A 1 665 ? 117.323 102.760 130.579 1.00 16.96  ? 665 ALA A C   1 
ATOM   4429  O O   . ALA A 1 665 ? 116.793 101.657 130.581 1.00 26.32  ? 665 ALA A O   1 
ATOM   4430  C CB  . ALA A 1 665 ? 117.629 104.193 128.510 1.00 10.43  ? 665 ALA A CB  1 
ATOM   4431  N N   . ILE A 1 666 ? 118.363 103.033 131.365 1.00 18.55  ? 666 ILE A N   1 
ATOM   4432  C CA  . ILE A 1 666 ? 118.971 102.071 132.296 1.00 20.00  ? 666 ILE A CA  1 
ATOM   4433  C C   . ILE A 1 666 ? 117.958 101.599 133.347 1.00 18.44  ? 666 ILE A C   1 
ATOM   4434  O O   . ILE A 1 666 ? 117.831 100.406 133.599 1.00 27.29  ? 666 ILE A O   1 
ATOM   4435  C CB  . ILE A 1 666 ? 120.228 102.711 132.932 1.00 18.56  ? 666 ILE A CB  1 
ATOM   4436  C CG1 . ILE A 1 666 ? 121.343 102.840 131.877 1.00 20.01  ? 666 ILE A CG1 1 
ATOM   4437  C CG2 . ILE A 1 666 ? 120.743 101.919 134.140 1.00 22.12  ? 666 ILE A CG2 1 
ATOM   4438  C CD1 . ILE A 1 666 ? 122.386 103.902 132.219 1.00 27.66  ? 666 ILE A CD1 1 
ATOM   4439  N N   . SER A 1 667 ? 117.238 102.551 133.947 1.00 25.73  ? 667 SER A N   1 
ATOM   4440  C CA  . SER A 1 667 ? 116.207 102.198 134.958 1.00 19.55  ? 667 SER A CA  1 
ATOM   4441  C C   . SER A 1 667 ? 115.172 101.261 134.330 1.00 18.07  ? 667 SER A C   1 
ATOM   4442  O O   . SER A 1 667 ? 114.880 100.211 134.935 1.00 31.07  ? 667 SER A O   1 
ATOM   4443  C CB  . SER A 1 667 ? 115.556 103.436 135.518 1.00 19.35  ? 667 SER A CB  1 
ATOM   4444  O OG  . SER A 1 667 ? 114.502 103.093 136.405 1.00 40.37  ? 667 SER A OG  1 
ATOM   4445  N N   . VAL A 1 668 ? 114.644 101.632 133.160 1.00 19.77  ? 668 VAL A N   1 
ATOM   4446  C CA  . VAL A 1 668 ? 113.602 100.804 132.479 1.00 20.02  ? 668 VAL A CA  1 
ATOM   4447  C C   . VAL A 1 668 ? 114.175 99.414  132.188 1.00 21.86  ? 668 VAL A C   1 
ATOM   4448  O O   . VAL A 1 668 ? 113.563 98.423  132.635 1.00 32.11  ? 668 VAL A O   1 
ATOM   4449  C CB  . VAL A 1 668 ? 113.103 101.483 131.189 1.00 22.81  ? 668 VAL A CB  1 
ATOM   4450  C CG1 . VAL A 1 668 ? 112.352 100.511 130.292 1.00 28.11  ? 668 VAL A CG1 1 
ATOM   4451  C CG2 . VAL A 1 668 ? 112.253 102.709 131.486 1.00 19.96  ? 668 VAL A CG2 1 
ATOM   4452  N N   . LEU A 1 669 ? 115.300 99.343  131.470 1.00 26.68  ? 669 LEU A N   1 
ATOM   4453  C CA  . LEU A 1 669 ? 115.857 98.051  131.093 1.00 21.37  ? 669 LEU A CA  1 
ATOM   4454  C C   . LEU A 1 669 ? 116.107 97.152  132.307 1.00 27.76  ? 669 LEU A C   1 
ATOM   4455  O O   . LEU A 1 669 ? 116.072 95.935  132.173 1.00 34.29  ? 669 LEU A O   1 
ATOM   4456  C CB  . LEU A 1 669 ? 117.128 98.287  130.269 1.00 24.50  ? 669 LEU A CB  1 
ATOM   4457  C CG  . LEU A 1 669 ? 116.836 98.936  128.904 1.00 25.97  ? 669 LEU A CG  1 
ATOM   4458  C CD1 . LEU A 1 669 ? 118.106 99.534  128.320 1.00 24.15  ? 669 LEU A CD1 1 
ATOM   4459  C CD2 . LEU A 1 669 ? 116.286 97.931  127.903 1.00 26.69  ? 669 LEU A CD2 1 
ATOM   4460  N N   . GLU A 1 670 ? 116.297 97.718  133.500 1.00 35.20  ? 670 GLU A N   1 
ATOM   4461  C CA  . GLU A 1 670 ? 116.289 96.973  134.755 1.00 22.19  ? 670 GLU A CA  1 
ATOM   4462  C C   . GLU A 1 670 ? 114.883 96.573  135.213 1.00 31.54  ? 670 GLU A C   1 
ATOM   4463  O O   . GLU A 1 670 ? 114.645 95.392  135.459 1.00 37.59  ? 670 GLU A O   1 
ATOM   4464  C CB  . GLU A 1 670 ? 117.019 97.779  135.837 1.00 30.07  ? 670 GLU A CB  1 
ATOM   4465  C CG  . GLU A 1 670 ? 118.534 97.586  135.734 1.00 36.49  ? 670 GLU A CG  1 
ATOM   4466  C CD  . GLU A 1 670 ? 118.917 96.116  135.939 1.00 43.32  ? 670 GLU A CD  1 
ATOM   4467  O OE1 . GLU A 1 670 ? 118.450 95.498  136.918 1.00 43.48  ? 670 GLU A OE1 1 
ATOM   4468  O OE2 . GLU A 1 670 ? 119.650 95.537  135.106 1.00 44.29  ? 670 GLU A OE2 1 
ATOM   4469  N N   . MET A 1 671 ? 113.938 97.516  135.273 1.00 30.15  ? 671 MET A N   1 
ATOM   4470  C CA  . MET A 1 671 ? 112.550 97.255  135.662 1.00 23.28  ? 671 MET A CA  1 
ATOM   4471  C C   . MET A 1 671 ? 111.829 96.239  134.773 1.00 32.08  ? 671 MET A C   1 
ATOM   4472  O O   . MET A 1 671 ? 111.003 95.483  135.273 1.00 35.75  ? 671 MET A O   1 
ATOM   4473  C CB  . MET A 1 671 ? 111.749 98.554  135.659 1.00 26.41  ? 671 MET A CB  1 
ATOM   4474  C CG  . MET A 1 671 ? 112.073 99.457  136.841 1.00 27.40  ? 671 MET A CG  1 
ATOM   4475  S SD  . MET A 1 671 ? 110.913 100.826 136.988 1.00 31.61  ? 671 MET A SD  1 
ATOM   4476  C CE  . MET A 1 671 ? 111.359 101.836 135.559 1.00 24.18  ? 671 MET A CE  1 
ATOM   4477  N N   . GLU A 1 672 ? 112.143 96.171  133.478 1.00 34.85  ? 672 GLU A N   1 
ATOM   4478  C CA  . GLU A 1 672 ? 111.579 95.179  132.561 1.00 27.38  ? 672 GLU A CA  1 
ATOM   4479  C C   . GLU A 1 672 ? 111.866 93.723  132.966 1.00 34.76  ? 672 GLU A C   1 
ATOM   4480  O O   . GLU A 1 672 ? 111.073 92.851  132.616 1.00 36.70  ? 672 GLU A O   1 
ATOM   4481  C CB  . GLU A 1 672 ? 112.098 95.414  131.137 1.00 34.24  ? 672 GLU A CB  1 
ATOM   4482  C CG  . GLU A 1 672 ? 111.317 96.501  130.399 1.00 32.34  ? 672 GLU A CG  1 
ATOM   4483  C CD  . GLU A 1 672 ? 111.726 96.582  128.924 1.00 40.21  ? 672 GLU A CD  1 
ATOM   4484  O OE1 . GLU A 1 672 ? 112.930 96.686  128.618 1.00 37.22  ? 672 GLU A OE1 1 
ATOM   4485  O OE2 . GLU A 1 672 ? 110.843 96.495  128.043 1.00 49.10  ? 672 GLU A OE2 1 
ATOM   4486  N N   . ASN A 1 673 ? 112.938 93.445  133.717 1.00 40.12  ? 673 ASN A N   1 
ATOM   4487  C CA  . ASN A 1 673 ? 113.225 92.109  134.266 1.00 39.97  ? 673 ASN A CA  1 
ATOM   4488  C C   . ASN A 1 673 ? 112.372 91.753  135.498 1.00 41.63  ? 673 ASN A C   1 
ATOM   4489  O O   . ASN A 1 673 ? 112.356 90.600  135.925 1.00 46.28  ? 673 ASN A O   1 
ATOM   4490  C CB  . ASN A 1 673 ? 114.713 92.009  134.640 1.00 37.24  ? 673 ASN A CB  1 
ATOM   4491  C CG  . ASN A 1 673 ? 115.646 92.316  133.490 1.00 40.21  ? 673 ASN A CG  1 
ATOM   4492  O OD1 . ASN A 1 673 ? 115.518 91.799  132.391 1.00 43.54  ? 673 ASN A OD1 1 
ATOM   4493  N ND2 . ASN A 1 673 ? 116.610 93.170  133.699 1.00 42.89  ? 673 ASN A ND2 1 
ATOM   4494  N N   . GLY A 1 674 ? 111.684 92.727  136.100 1.00 37.14  ? 674 GLY A N   1 
ATOM   4495  C CA  . GLY A 1 674 ? 111.027 92.588  137.393 1.00 36.85  ? 674 GLY A CA  1 
ATOM   4496  C C   . GLY A 1 674 ? 112.014 92.480  138.553 1.00 32.26  ? 674 GLY A C   1 
ATOM   4497  O O   . GLY A 1 674 ? 113.150 92.940  138.477 1.00 38.21  ? 674 GLY A O   1 
ATOM   4498  N N   . TYR A 1 675 ? 111.568 91.894  139.653 1.00 37.80  ? 675 TYR A N   1 
ATOM   4499  C CA  . TYR A 1 675 ? 112.349 91.756  140.884 1.00 39.83  ? 675 TYR A CA  1 
ATOM   4500  C C   . TYR A 1 675 ? 113.131 90.439  140.958 1.00 37.77  ? 675 TYR A C   1 
ATOM   4501  O O   . TYR A 1 675 ? 112.755 89.459  140.311 1.00 48.94  ? 675 TYR A O   1 
ATOM   4502  C CB  . TYR A 1 675 ? 111.405 91.907  142.076 1.00 33.74  ? 675 TYR A CB  1 
ATOM   4503  C CG  . TYR A 1 675 ? 110.568 93.167  142.045 1.00 34.83  ? 675 TYR A CG  1 
ATOM   4504  C CD1 . TYR A 1 675 ? 111.197 94.422  142.145 1.00 33.98  ? 675 TYR A CD1 1 
ATOM   4505  C CD2 . TYR A 1 675 ? 109.173 93.093  141.915 1.00 39.07  ? 675 TYR A CD2 1 
ATOM   4506  C CE1 . TYR A 1 675 ? 110.435 95.599  142.106 1.00 32.58  ? 675 TYR A CE1 1 
ATOM   4507  C CE2 . TYR A 1 675 ? 108.405 94.272  141.893 1.00 38.54  ? 675 TYR A CE2 1 
ATOM   4508  C CZ  . TYR A 1 675 ? 109.034 95.525  141.985 1.00 34.97  ? 675 TYR A CZ  1 
ATOM   4509  O OH  . TYR A 1 675 ? 108.284 96.655  141.960 1.00 34.66  ? 675 TYR A OH  1 
ATOM   4510  N N   . TRP A 1 676 ? 114.160 90.374  141.804 1.00 33.06  ? 676 TRP A N   1 
ATOM   4511  C CA  . TRP A 1 676 ? 115.021 89.191  141.958 1.00 32.98  ? 676 TRP A CA  1 
ATOM   4512  C C   . TRP A 1 676 ? 114.240 87.917  142.317 1.00 36.33  ? 676 TRP A C   1 
ATOM   4513  O O   . TRP A 1 676 ? 114.597 86.827  141.875 1.00 45.04  ? 676 TRP A O   1 
ATOM   4514  C CB  . TRP A 1 676 ? 116.114 89.487  143.000 1.00 34.51  ? 676 TRP A CB  1 
ATOM   4515  C CG  . TRP A 1 676 ? 115.678 89.718  144.417 1.00 34.40  ? 676 TRP A CG  1 
ATOM   4516  C CD1 . TRP A 1 676 ? 115.406 90.919  144.970 1.00 35.81  ? 676 TRP A CD1 1 
ATOM   4517  C CD2 . TRP A 1 676 ? 115.425 88.738  145.471 1.00 37.28  ? 676 TRP A CD2 1 
ATOM   4518  N NE1 . TRP A 1 676 ? 115.012 90.755  146.280 1.00 33.64  ? 676 TRP A NE1 1 
ATOM   4519  C CE2 . TRP A 1 676 ? 114.968 89.428  146.631 1.00 35.62  ? 676 TRP A CE2 1 
ATOM   4520  C CE3 . TRP A 1 676 ? 115.507 87.332  145.559 1.00 38.08  ? 676 TRP A CE3 1 
ATOM   4521  C CZ2 . TRP A 1 676 ? 114.583 88.762  147.799 1.00 40.63  ? 676 TRP A CZ2 1 
ATOM   4522  C CZ3 . TRP A 1 676 ? 115.119 86.653  146.728 1.00 36.13  ? 676 TRP A CZ3 1 
ATOM   4523  C CH2 . TRP A 1 676 ? 114.647 87.362  147.841 1.00 40.41  ? 676 TRP A CH2 1 
ATOM   4524  N N   . TRP A 1 677 ? 113.150 88.057  143.065 1.00 36.99  ? 677 TRP A N   1 
ATOM   4525  C CA  . TRP A 1 677 ? 112.249 86.993  143.505 1.00 36.20  ? 677 TRP A CA  1 
ATOM   4526  C C   . TRP A 1 677 ? 111.068 86.732  142.555 1.00 41.49  ? 677 TRP A C   1 
ATOM   4527  O O   . TRP A 1 677 ? 110.388 85.719  142.708 1.00 45.96  ? 677 TRP A O   1 
ATOM   4528  C CB  . TRP A 1 677 ? 111.731 87.395  144.892 1.00 38.41  ? 677 TRP A CB  1 
ATOM   4529  C CG  . TRP A 1 677 ? 110.971 88.682  144.921 1.00 36.04  ? 677 TRP A CG  1 
ATOM   4530  C CD1 . TRP A 1 677 ? 111.515 89.903  145.108 1.00 29.48  ? 677 TRP A CD1 1 
ATOM   4531  C CD2 . TRP A 1 677 ? 109.545 88.915  144.715 1.00 37.91  ? 677 TRP A CD2 1 
ATOM   4532  N NE1 . TRP A 1 677 ? 110.537 90.865  145.014 1.00 29.14  ? 677 TRP A NE1 1 
ATOM   4533  C CE2 . TRP A 1 677 ? 109.309 90.319  144.735 1.00 35.67  ? 677 TRP A CE2 1 
ATOM   4534  C CE3 . TRP A 1 677 ? 108.426 88.082  144.502 1.00 37.55  ? 677 TRP A CE3 1 
ATOM   4535  C CZ2 . TRP A 1 677 ? 108.040 90.873  144.529 1.00 37.12  ? 677 TRP A CZ2 1 
ATOM   4536  C CZ3 . TRP A 1 677 ? 107.144 88.628  144.314 1.00 40.16  ? 677 TRP A CZ3 1 
ATOM   4537  C CH2 . TRP A 1 677 ? 106.949 90.020  144.322 1.00 39.88  ? 677 TRP A CH2 1 
ATOM   4538  N N   . CYS A 1 678 ? 110.784 87.627  141.600 1.00 46.18  ? 678 CYS A N   1 
ATOM   4539  C CA  . CYS A 1 678 ? 109.558 87.603  140.792 1.00 45.03  ? 678 CYS A CA  1 
ATOM   4540  C C   . CYS A 1 678 ? 109.802 87.286  139.306 1.00 50.06  ? 678 CYS A C   1 
ATOM   4541  O O   . CYS A 1 678 ? 109.023 86.549  138.703 1.00 54.39  ? 678 CYS A O   1 
ATOM   4542  C CB  . CYS A 1 678 ? 108.822 88.934  140.984 1.00 48.15  ? 678 CYS A CB  1 
ATOM   4543  S SG  . CYS A 1 678 ? 107.129 88.810  140.344 1.00 62.86  ? 678 CYS A SG  1 
ATOM   4544  N N   . ARG A 1 679 ? 110.988 87.704  138.799 1.00 53.64  ? 679 ARG A N   1 
ATOM   4545  C CA  . ARG A 1 679 ? 111.474 87.287  137.447 1.00 55.54  ? 679 ARG A CA  1 
ATOM   4546  C C   . ARG A 1 679 ? 110.299 87.277  136.460 1.00 52.92  ? 679 ARG A C   1 
ATOM   4547  O O   . ARG A 1 679 ? 109.840 86.171  136.115 1.00 54.57  ? 679 ARG A O   1 
ATOM   4548  C CB  . ARG A 1 679 ? 112.107 85.904  137.730 1.00 57.64  ? 679 ARG A CB  1 
ATOM   4549  C CG  . ARG A 1 679 ? 113.383 85.621  136.931 1.00 56.69  ? 679 ARG A CG  1 
ATOM   4550  C CD  . ARG A 1 679 ? 114.588 86.425  137.434 1.00 55.39  ? 679 ARG A CD  1 
ATOM   4551  N NE  . ARG A 1 679 ? 114.924 86.176  138.829 1.00 55.28  ? 679 ARG A NE  1 
ATOM   4552  C CZ  . ARG A 1 679 ? 115.849 85.316  139.236 1.00 59.48  ? 679 ARG A CZ  1 
ATOM   4553  N NH1 . ARG A 1 679 ? 116.087 85.159  140.527 1.00 58.47  ? 679 ARG A NH1 1 
ATOM   4554  N NH2 . ARG A 1 679 ? 116.538 84.617  138.352 1.00 56.61  ? 679 ARG A NH2 1 
ATOM   4555  N N   . ARG A 1 680 ? 109.838 88.451  136.016 1.00 53.43  ? 680 ARG A N   1 
ATOM   4556  C CA  . ARG A 1 680 ? 108.680 88.603  135.108 1.00 53.71  ? 680 ARG A CA  1 
ATOM   4557  C C   . ARG A 1 680 ? 108.953 88.280  133.627 1.00 54.05  ? 680 ARG A C   1 
ATOM   4558  O O   . ARG A 1 680 ? 110.044 88.514  133.111 1.00 53.98  ? 680 ARG A O   1 
ATOM   4559  C CB  . ARG A 1 680 ? 108.028 89.991  135.276 1.00 52.08  ? 680 ARG A CB  1 
ATOM   4560  C CG  . ARG A 1 680 ? 108.656 91.103  134.428 1.00 48.15  ? 680 ARG A CG  1 
ATOM   4561  C CD  . ARG A 1 680 ? 107.962 92.446  134.641 1.00 48.73  ? 680 ARG A CD  1 
ATOM   4562  N NE  . ARG A 1 680 ? 108.218 93.349  133.508 1.00 57.88  ? 680 ARG A NE  1 
ATOM   4563  C CZ  . ARG A 1 680 ? 107.466 94.363  133.118 1.00 54.36  ? 680 ARG A CZ  1 
ATOM   4564  N NH1 . ARG A 1 680 ? 107.690 94.955  131.985 1.00 49.68  ? 680 ARG A NH1 1 
ATOM   4565  N NH2 . ARG A 1 680 ? 106.471 94.799  133.828 1.00 50.11  ? 680 ARG A NH2 1 
ATOM   4566  N N   . LYS A 1 681 ? 107.917 87.811  132.924 1.00 60.46  ? 681 LYS A N   1 
ATOM   4567  C CA  . LYS A 1 681 ? 107.892 87.599  131.463 1.00 62.30  ? 681 LYS A CA  1 
ATOM   4568  C C   . LYS A 1 681 ? 107.762 88.933  130.709 1.00 61.38  ? 681 LYS A C   1 
ATOM   4569  O O   . LYS A 1 681 ? 106.979 89.794  131.105 1.00 56.75  ? 681 LYS A O   1 
ATOM   4570  N N   . LYS A 1 682 ? 108.520 89.103  129.621 1.00 55.28  ? 682 LYS A N   1 
ATOM   4571  C CA  . LYS A 1 682 ? 108.516 90.302  128.760 1.00 56.31  ? 682 LYS A CA  1 
ATOM   4572  C C   . LYS A 1 682 ? 107.512 90.190  127.608 1.00 56.33  ? 682 LYS A C   1 
ATOM   4573  O O   . LYS A 1 682 ? 107.128 89.091  127.215 1.00 58.56  ? 682 LYS A O   1 
ATOM   4574  C CB  . LYS A 1 682 ? 109.941 90.560  128.236 1.00 53.05  ? 682 LYS A CB  1 
ATOM   4575  C CG  . LYS A 1 682 ? 110.921 90.809  129.388 1.00 51.98  ? 682 LYS A CG  1 
ATOM   4576  C CD  . LYS A 1 682 ? 112.316 91.171  128.890 1.00 52.69  ? 682 LYS A CD  1 
ATOM   4577  C CE  . LYS A 1 682 ? 113.237 91.344  130.095 1.00 53.91  ? 682 LYS A CE  1 
ATOM   4578  N NZ  . LYS A 1 682 ? 114.641 91.572  129.699 1.00 55.29  ? 682 LYS A NZ  1 
ATOM   4579  N N   . HIS A 1 683 ? 107.129 91.319  127.013 1.00 49.53  ? 683 HIS A N   1 
ATOM   4580  C CA  . HIS A 1 683 ? 106.286 91.381  125.812 1.00 51.95  ? 683 HIS A CA  1 
ATOM   4581  C C   . HIS A 1 683 ? 107.006 92.101  124.661 1.00 53.17  ? 683 HIS A C   1 
ATOM   4582  O O   . HIS A 1 683 ? 107.816 93.003  124.948 1.00 53.04  ? 683 HIS A O   1 
ATOM   4583  C CB  . HIS A 1 683 ? 104.964 92.090  126.132 1.00 55.29  ? 683 HIS A CB  1 
ATOM   4584  C CG  . HIS A 1 683 ? 105.089 93.576  126.202 1.00 55.70  ? 683 HIS A CG  1 
ATOM   4585  N ND1 . HIS A 1 683 ? 105.427 94.234  127.368 1.00 55.07  ? 683 HIS A ND1 1 
ATOM   4586  C CD2 . HIS A 1 683 ? 104.932 94.530  125.259 1.00 52.58  ? 683 HIS A CD2 1 
ATOM   4587  C CE1 . HIS A 1 683 ? 105.468 95.532  127.141 1.00 55.80  ? 683 HIS A CE1 1 
ATOM   4588  N NE2 . HIS A 1 683 ? 105.167 95.739  125.854 1.00 53.51  ? 683 HIS A NE2 1 
ATOM   4589  N N   . ARG A 1 684 ? 106.718 91.712  123.413 1.00 45.86  ? 684 ARG A N   1 
ATOM   4590  C CA  . ARG A 1 684 ? 107.240 92.396  122.222 1.00 38.72  ? 684 ARG A CA  1 
ATOM   4591  C C   . ARG A 1 684 ? 106.579 93.753  122.028 1.00 42.71  ? 684 ARG A C   1 
ATOM   4592  O O   . ARG A 1 684 ? 105.374 93.890  122.234 1.00 42.33  ? 684 ARG A O   1 
ATOM   4593  C CB  . ARG A 1 684 ? 107.029 91.563  120.953 1.00 41.19  ? 684 ARG A CB  1 
ATOM   4594  C CG  . ARG A 1 684 ? 107.789 90.245  121.016 1.00 42.45  ? 684 ARG A CG  1 
ATOM   4595  C CD  . ARG A 1 684 ? 107.932 89.575  119.655 1.00 39.06  ? 684 ARG A CD  1 
ATOM   4596  N NE  . ARG A 1 684 ? 108.958 90.248  118.842 1.00 35.80  ? 684 ARG A NE  1 
ATOM   4597  C CZ  . ARG A 1 684 ? 109.798 89.677  118.004 1.00 42.11  ? 684 ARG A CZ  1 
ATOM   4598  N NH1 . ARG A 1 684 ? 110.745 90.374  117.453 1.00 44.63  ? 684 ARG A NH1 1 
ATOM   4599  N NH2 . ARG A 1 684 ? 109.733 88.415  117.704 1.00 42.48  ? 684 ARG A NH2 1 
ATOM   4600  N N   . GLU A 1 685 ? 107.339 94.718  121.535 1.00 42.30  ? 685 GLU A N   1 
ATOM   4601  C CA  . GLU A 1 685 ? 106.815 96.012  121.112 1.00 38.72  ? 685 GLU A CA  1 
ATOM   4602  C C   . GLU A 1 685 ? 106.841 96.209  119.596 1.00 45.53  ? 685 GLU A C   1 
ATOM   4603  O O   . GLU A 1 685 ? 107.433 95.433  118.846 1.00 50.64  ? 685 GLU A O   1 
ATOM   4604  C CB  . GLU A 1 685 ? 107.496 97.131  121.900 1.00 39.49  ? 685 GLU A CB  1 
ATOM   4605  C CG  . GLU A 1 685 ? 106.973 97.034  123.338 1.00 46.41  ? 685 GLU A CG  1 
ATOM   4606  C CD  . GLU A 1 685 ? 107.634 98.039  124.262 1.00 45.56  ? 685 GLU A CD  1 
ATOM   4607  O OE1 . GLU A 1 685 ? 107.576 99.247  123.956 1.00 44.43  ? 685 GLU A OE1 1 
ATOM   4608  O OE2 . GLU A 1 685 ? 108.179 97.599  125.298 1.00 51.88  ? 685 GLU A OE2 1 
ATOM   4609  N N   . GLY A 1 686 ? 106.105 97.217  119.130 1.00 39.36  ? 686 GLY A N   1 
ATOM   4610  C CA  . GLY A 1 686 ? 105.655 97.271  117.746 1.00 37.17  ? 686 GLY A CA  1 
ATOM   4611  C C   . GLY A 1 686 ? 104.612 96.198  117.432 1.00 37.92  ? 686 GLY A C   1 
ATOM   4612  O O   . GLY A 1 686 ? 104.019 95.594  118.328 1.00 42.37  ? 686 GLY A O   1 
ATOM   4613  N N   . ARG A 1 687 ? 104.366 95.969  116.148 1.00 45.69  ? 687 ARG A N   1 
ATOM   4614  C CA  . ARG A 1 687 ? 103.433 94.970  115.615 1.00 45.41  ? 687 ARG A CA  1 
ATOM   4615  C C   . ARG A 1 687 ? 104.110 94.172  114.519 1.00 44.80  ? 687 ARG A C   1 
ATOM   4616  O O   . ARG A 1 687 ? 104.915 94.721  113.772 1.00 49.27  ? 687 ARG A O   1 
ATOM   4617  C CB  . ARG A 1 687 ? 102.175 95.648  115.058 1.00 47.02  ? 687 ARG A CB  1 
ATOM   4618  C CG  . ARG A 1 687 ? 101.293 96.271  116.144 1.00 48.17  ? 687 ARG A CG  1 
ATOM   4619  C CD  . ARG A 1 687 ? 100.017 96.883  115.556 1.00 52.84  ? 687 ARG A CD  1 
ATOM   4620  N NE  . ARG A 1 687 ? 99.149  95.865  114.931 1.00 56.40  ? 687 ARG A NE  1 
ATOM   4621  C CZ  . ARG A 1 687 ? 97.961  96.055  114.394 1.00 54.61  ? 687 ARG A CZ  1 
ATOM   4622  N NH1 . ARG A 1 687 ? 97.335  95.073  113.819 1.00 54.95  ? 687 ARG A NH1 1 
ATOM   4623  N NH2 . ARG A 1 687 ? 97.367  97.213  114.412 1.00 52.05  ? 687 ARG A NH2 1 
ATOM   4624  N N   . LEU A 1 688 ? 103.763 92.899  114.377 1.00 41.32  ? 688 LEU A N   1 
ATOM   4625  C CA  . LEU A 1 688 ? 104.134 92.117  113.199 1.00 41.24  ? 688 LEU A CA  1 
ATOM   4626  C C   . LEU A 1 688 ? 103.360 92.629  111.975 1.00 42.89  ? 688 LEU A C   1 
ATOM   4627  O O   . LEU A 1 688 ? 102.142 92.485  111.908 1.00 49.03  ? 688 LEU A O   1 
ATOM   4628  C CB  . LEU A 1 688 ? 103.873 90.633  113.489 1.00 45.49  ? 688 LEU A CB  1 
ATOM   4629  C CG  . LEU A 1 688 ? 104.255 89.682  112.349 1.00 42.36  ? 688 LEU A CG  1 
ATOM   4630  C CD1 . LEU A 1 688 ? 105.727 89.812  111.964 1.00 43.14  ? 688 LEU A CD1 1 
ATOM   4631  C CD2 . LEU A 1 688 ? 104.007 88.247  112.798 1.00 46.61  ? 688 LEU A CD2 1 
ATOM   4632  N N   . LEU A 1 689 ? 104.057 93.249  111.023 1.00 44.88  ? 689 LEU A N   1 
ATOM   4633  C CA  . LEU A 1 689 ? 103.487 93.892  109.835 1.00 47.47  ? 689 LEU A CA  1 
ATOM   4634  C C   . LEU A 1 689 ? 104.235 93.464  108.571 1.00 50.99  ? 689 LEU A C   1 
ATOM   4635  O O   . LEU A 1 689 ? 105.457 93.314  108.587 1.00 53.69  ? 689 LEU A O   1 
ATOM   4636  C CB  . LEU A 1 689 ? 103.537 95.427  109.979 1.00 46.69  ? 689 LEU A CB  1 
ATOM   4637  C CG  . LEU A 1 689 ? 102.715 96.010  111.139 1.00 52.28  ? 689 LEU A CG  1 
ATOM   4638  C CD1 . LEU A 1 689 ? 102.993 97.502  111.261 1.00 50.58  ? 689 LEU A CD1 1 
ATOM   4639  C CD2 . LEU A 1 689 ? 101.211 95.830  110.946 1.00 51.59  ? 689 LEU A CD2 1 
ATOM   4640  N N   . LYS A 1 690 ? 103.514 93.306  107.457 1.00 59.06  ? 690 LYS A N   1 
ATOM   4641  C CA  . LYS A 1 690 ? 104.109 93.142  106.125 1.00 60.16  ? 690 LYS A CA  1 
ATOM   4642  C C   . LYS A 1 690 ? 104.620 94.487  105.603 1.00 58.89  ? 690 LYS A C   1 
ATOM   4643  O O   . LYS A 1 690 ? 103.871 95.460  105.577 1.00 57.43  ? 690 LYS A O   1 
ATOM   4644  C CB  . LYS A 1 690 ? 103.088 92.506  105.168 1.00 60.92  ? 690 LYS A CB  1 
ATOM   4645  C CG  . LYS A 1 690 ? 103.723 92.147  103.816 1.00 61.74  ? 690 LYS A CG  1 
ATOM   4646  C CD  . LYS A 1 690 ? 102.682 91.565  102.857 1.00 61.97  ? 690 LYS A CD  1 
ATOM   4647  C CE  . LYS A 1 690 ? 103.286 91.388  101.466 1.00 63.99  ? 690 LYS A CE  1 
ATOM   4648  N NZ  . LYS A 1 690 ? 102.275 90.934  100.487 1.00 62.31  ? 690 LYS A NZ  1 
ATOM   4649  N N   . VAL A 1 691 ? 105.873 94.531  105.154 1.00 55.27  ? 691 VAL A N   1 
ATOM   4650  C CA  . VAL A 1 691 ? 106.526 95.737  104.608 1.00 57.78  ? 691 VAL A CA  1 
ATOM   4651  C C   . VAL A 1 691 ? 106.902 95.614  103.122 1.00 56.02  ? 691 VAL A C   1 
ATOM   4652  O O   . VAL A 1 691 ? 107.220 96.617  102.486 1.00 53.82  ? 691 VAL A O   1 
ATOM   4653  C CB  . VAL A 1 691 ? 107.734 96.162  105.471 1.00 52.48  ? 691 VAL A CB  1 
ATOM   4654  C CG1 . VAL A 1 691 ? 107.314 96.522  106.899 1.00 46.28  ? 691 VAL A CG1 1 
ATOM   4655  C CG2 . VAL A 1 691 ? 108.827 95.097  105.552 1.00 50.63  ? 691 VAL A CG2 1 
ATOM   4656  N N   . GLY A 1 692 ? 106.823 94.416  102.537 1.00 63.77  ? 692 GLY A N   1 
ATOM   4657  C CA  . GLY A 1 692 ? 107.123 94.163  101.124 1.00 64.55  ? 692 GLY A CA  1 
ATOM   4658  C C   . GLY A 1 692 ? 107.222 92.671  100.806 1.00 69.59  ? 692 GLY A C   1 
ATOM   4659  O O   . GLY A 1 692 ? 106.534 91.859  101.426 1.00 69.93  ? 692 GLY A O   1 
ATOM   4660  N N   . THR A 1 693 ? 108.110 92.294  99.879  1.00 75.77  ? 693 THR A N   1 
ATOM   4661  C CA  . THR A 1 693 ? 108.486 90.897  99.572  1.00 75.33  ? 693 THR A CA  1 
ATOM   4662  C C   . THR A 1 693 ? 110.004 90.716  99.706  1.00 74.67  ? 693 THR A C   1 
ATOM   4663  O O   . THR A 1 693 ? 110.761 91.609  99.322  1.00 75.02  ? 693 THR A O   1 
ATOM   4664  C CB  . THR A 1 693 ? 108.000 90.489  98.171  1.00 76.07  ? 693 THR A CB  1 
ATOM   4665  O OG1 . THR A 1 693 ? 106.598 90.631  98.085  1.00 75.68  ? 693 THR A OG1 1 
ATOM   4666  C CG2 . THR A 1 693 ? 108.313 89.033  97.830  1.00 75.35  ? 693 THR A CG2 1 
ATOM   4667  N N   . ARG A 1 694 ? 110.466 89.594  100.276 1.00 77.02  ? 694 ARG A N   1 
ATOM   4668  C CA  . ARG A 1 694 ? 111.881 89.392  100.648 1.00 78.69  ? 694 ARG A CA  1 
ATOM   4669  C CB  . ARG A 1 694 ? 112.043 88.148  101.541 1.00 77.78  ? 694 ARG A CB  1 
ATOM   4670  C CG  . ARG A 1 694 ? 111.235 88.246  102.842 1.00 77.72  ? 694 ARG A CG  1 
ATOM   4671  C CD  . ARG A 1 694 ? 111.497 87.061  103.777 1.00 78.66  ? 694 ARG A CD  1 
ATOM   4672  N NE  . ARG A 1 694 ? 112.828 87.138  104.407 1.00 81.21  ? 694 ARG A NE  1 
ATOM   4673  C CZ  . ARG A 1 694 ? 113.386 86.224  105.178 1.00 81.40  ? 694 ARG A CZ  1 
ATOM   4674  N NH1 . ARG A 1 694 ? 114.559 86.433  105.697 1.00 78.98  ? 694 ARG A NH1 1 
ATOM   4675  N NH2 . ARG A 1 694 ? 112.806 85.092  105.449 1.00 78.90  ? 694 ARG A NH2 1 
ATOM   4676  N N   . PRO A 1 699 ? 106.401 86.867  101.476 1.00 77.00  ? 699 PRO A N   1 
ATOM   4677  C CA  . PRO A 1 699 ? 106.201 88.185  102.060 1.00 78.11  ? 699 PRO A CA  1 
ATOM   4678  C C   . PRO A 1 699 ? 107.286 88.543  103.086 1.00 77.42  ? 699 PRO A C   1 
ATOM   4679  O O   . PRO A 1 699 ? 107.807 87.686  103.801 1.00 74.98  ? 699 PRO A O   1 
ATOM   4680  C CB  . PRO A 1 699 ? 104.813 88.132  102.699 1.00 76.40  ? 699 PRO A CB  1 
ATOM   4681  C CG  . PRO A 1 699 ? 104.660 86.662  103.074 1.00 75.94  ? 699 PRO A CG  1 
ATOM   4682  C CD  . PRO A 1 699 ? 105.383 85.947  101.939 1.00 76.68  ? 699 PRO A CD  1 
ATOM   4683  N N   . ASP A 1 700 ? 107.619 89.831  103.170 1.00 67.57  ? 700 ASP A N   1 
ATOM   4684  C CA  . ASP A 1 700 ? 108.536 90.390  104.169 1.00 67.15  ? 700 ASP A CA  1 
ATOM   4685  C C   . ASP A 1 700 ? 107.732 90.915  105.364 1.00 66.10  ? 700 ASP A C   1 
ATOM   4686  O O   . ASP A 1 700 ? 107.165 92.007  105.307 1.00 64.84  ? 700 ASP A O   1 
ATOM   4687  C CB  . ASP A 1 700 ? 109.392 91.481  103.503 1.00 66.65  ? 700 ASP A CB  1 
ATOM   4688  C CG  . ASP A 1 700 ? 110.523 92.026  104.379 1.00 69.39  ? 700 ASP A CG  1 
ATOM   4689  O OD1 . ASP A 1 700 ? 110.707 91.579  105.529 1.00 66.68  ? 700 ASP A OD1 1 
ATOM   4690  O OD2 . ASP A 1 700 ? 111.271 92.901  103.896 1.00 67.74  ? 700 ASP A OD2 1 
ATOM   4691  N N   . GLU A 1 701 ? 107.617 90.109  106.420 1.00 61.62  ? 701 GLU A N   1 
ATOM   4692  C CA  . GLU A 1 701 ? 106.906 90.456  107.653 1.00 61.01  ? 701 GLU A CA  1 
ATOM   4693  C C   . GLU A 1 701 ? 107.883 90.684  108.805 1.00 59.21  ? 701 GLU A C   1 
ATOM   4694  O O   . GLU A 1 701 ? 108.741 89.841  109.073 1.00 61.25  ? 701 GLU A O   1 
ATOM   4695  C CB  . GLU A 1 701 ? 105.884 89.374  108.028 1.00 62.17  ? 701 GLU A CB  1 
ATOM   4696  C CG  . GLU A 1 701 ? 104.738 89.268  107.018 1.00 62.52  ? 701 GLU A CG  1 
ATOM   4697  C CD  . GLU A 1 701 ? 103.606 88.371  107.537 1.00 64.57  ? 701 GLU A CD  1 
ATOM   4698  O OE1 . GLU A 1 701 ? 103.875 87.225  107.954 1.00 63.18  ? 701 GLU A OE1 1 
ATOM   4699  O OE2 . GLU A 1 701 ? 102.435 88.801  107.516 1.00 62.51  ? 701 GLU A OE2 1 
ATOM   4700  N N   . ARG A 1 702 ? 107.746 91.810  109.507 1.00 48.02  ? 702 ARG A N   1 
ATOM   4701  C CA  . ARG A 1 702 ? 108.662 92.238  110.574 1.00 39.04  ? 702 ARG A CA  1 
ATOM   4702  C C   . ARG A 1 702 ? 107.930 92.849  111.747 1.00 38.77  ? 702 ARG A C   1 
ATOM   4703  O O   . ARG A 1 702 ? 106.870 93.436  111.581 1.00 44.04  ? 702 ARG A O   1 
ATOM   4704  C CB  . ARG A 1 702 ? 109.650 93.282  110.047 1.00 40.84  ? 702 ARG A CB  1 
ATOM   4705  C CG  . ARG A 1 702 ? 110.359 92.847  108.772 1.00 43.13  ? 702 ARG A CG  1 
ATOM   4706  C CD  . ARG A 1 702 ? 111.519 93.785  108.519 1.00 40.16  ? 702 ARG A CD  1 
ATOM   4707  N NE  . ARG A 1 702 ? 112.022 93.617  107.163 1.00 41.94  ? 702 ARG A NE  1 
ATOM   4708  C CZ  . ARG A 1 702 ? 112.983 94.323  106.621 1.00 40.72  ? 702 ARG A CZ  1 
ATOM   4709  N NH1 . ARG A 1 702 ? 113.148 94.271  105.343 1.00 39.35  ? 702 ARG A NH1 1 
ATOM   4710  N NH2 . ARG A 1 702 ? 113.761 95.099  107.320 1.00 41.77  ? 702 ARG A NH2 1 
ATOM   4711  N N   . TRP A 1 703 ? 108.530 92.760  112.925 1.00 41.81  ? 703 TRP A N   1 
ATOM   4712  C CA  . TRP A 1 703 ? 108.110 93.533  114.087 1.00 38.11  ? 703 TRP A CA  1 
ATOM   4713  C C   . TRP A 1 703 ? 108.550 94.982  113.917 1.00 35.52  ? 703 TRP A C   1 
ATOM   4714  O O   . TRP A 1 703 ? 109.731 95.316  113.977 1.00 34.30  ? 703 TRP A O   1 
ATOM   4715  C CB  . TRP A 1 703 ? 108.628 92.881  115.360 1.00 37.41  ? 703 TRP A CB  1 
ATOM   4716  C CG  . TRP A 1 703 ? 107.849 91.652  115.689 1.00 37.16  ? 703 TRP A CG  1 
ATOM   4717  C CD1 . TRP A 1 703 ? 108.049 90.421  115.166 1.00 38.88  ? 703 TRP A CD1 1 
ATOM   4718  C CD2 . TRP A 1 703 ? 106.665 91.537  116.527 1.00 39.16  ? 703 TRP A CD2 1 
ATOM   4719  N NE1 . TRP A 1 703 ? 107.082 89.557  115.630 1.00 40.56  ? 703 TRP A NE1 1 
ATOM   4720  C CE2 . TRP A 1 703 ? 106.199 90.191  116.471 1.00 38.91  ? 703 TRP A CE2 1 
ATOM   4721  C CE3 . TRP A 1 703 ? 105.945 92.431  117.348 1.00 37.66  ? 703 TRP A CE3 1 
ATOM   4722  C CZ2 . TRP A 1 703 ? 105.077 89.754  117.185 1.00 35.37  ? 703 TRP A CZ2 1 
ATOM   4723  C CZ3 . TRP A 1 703 ? 104.824 92.001  118.079 1.00 38.85  ? 703 TRP A CZ3 1 
ATOM   4724  C CH2 . TRP A 1 703 ? 104.390 90.666  117.998 1.00 40.49  ? 703 TRP A CH2 1 
ATOM   4725  N N   . CYS A 1 704 ? 107.568 95.829  113.652 1.00 39.05  ? 704 CYS A N   1 
ATOM   4726  C CA  . CYS A 1 704 ? 107.750 97.209  113.249 1.00 32.65  ? 704 CYS A CA  1 
ATOM   4727  C C   . CYS A 1 704 ? 107.065 98.143  114.235 1.00 30.99  ? 704 CYS A C   1 
ATOM   4728  O O   . CYS A 1 704 ? 105.974 97.869  114.726 1.00 42.15  ? 704 CYS A O   1 
ATOM   4729  C CB  . CYS A 1 704 ? 107.207 97.394  111.828 1.00 33.76  ? 704 CYS A CB  1 
ATOM   4730  S SG  . CYS A 1 704 ? 108.519 97.062  110.630 1.00 52.07  ? 704 CYS A SG  1 
ATOM   4731  N N   . PHE A 1 705 ? 107.695 99.272  114.498 1.00 23.79  ? 705 PHE A N   1 
ATOM   4732  C CA  . PHE A 1 705 ? 107.230 100.275 115.438 1.00 22.82  ? 705 PHE A CA  1 
ATOM   4733  C C   . PHE A 1 705 ? 106.918 101.586 114.728 1.00 23.91  ? 705 PHE A C   1 
ATOM   4734  O O   . PHE A 1 705 ? 107.779 102.154 114.058 1.00 26.27  ? 705 PHE A O   1 
ATOM   4735  C CB  . PHE A 1 705 ? 108.312 100.395 116.496 1.00 26.86  ? 705 PHE A CB  1 
ATOM   4736  C CG  . PHE A 1 705 ? 108.042 101.357 117.624 1.00 27.04  ? 705 PHE A CG  1 
ATOM   4737  C CD1 . PHE A 1 705 ? 107.204 100.979 118.683 1.00 27.43  ? 705 PHE A CD1 1 
ATOM   4738  C CD2 . PHE A 1 705 ? 108.693 102.597 117.645 1.00 25.57  ? 705 PHE A CD2 1 
ATOM   4739  C CE1 . PHE A 1 705 ? 107.001 101.855 119.761 1.00 27.12  ? 705 PHE A CE1 1 
ATOM   4740  C CE2 . PHE A 1 705 ? 108.490 103.468 118.719 1.00 28.26  ? 705 PHE A CE2 1 
ATOM   4741  C CZ  . PHE A 1 705 ? 107.639 103.103 119.772 1.00 24.70  ? 705 PHE A CZ  1 
ATOM   4742  N N   . ARG A 1 706 ? 105.675 102.050 114.852 1.00 30.98  ? 706 ARG A N   1 
ATOM   4743  C CA  . ARG A 1 706 ? 105.177 103.273 114.230 1.00 25.36  ? 706 ARG A CA  1 
ATOM   4744  C C   . ARG A 1 706 ? 105.634 104.511 114.988 1.00 23.96  ? 706 ARG A C   1 
ATOM   4745  O O   . ARG A 1 706 ? 105.316 104.682 116.161 1.00 32.09  ? 706 ARG A O   1 
ATOM   4746  C CB  . ARG A 1 706 ? 103.652 103.169 114.119 1.00 30.40  ? 706 ARG A CB  1 
ATOM   4747  C CG  . ARG A 1 706 ? 103.036 104.334 113.346 1.00 31.63  ? 706 ARG A CG  1 
ATOM   4748  C CD  . ARG A 1 706 ? 101.534 104.137 113.149 1.00 34.00  ? 706 ARG A CD  1 
ATOM   4749  N NE  . ARG A 1 706 ? 101.254 103.082 112.165 1.00 35.80  ? 706 ARG A NE  1 
ATOM   4750  C CZ  . ARG A 1 706 ? 100.744 101.884 112.346 1.00 39.58  ? 706 ARG A CZ  1 
ATOM   4751  N NH1 . ARG A 1 706 ? 100.584 101.088 111.338 1.00 32.26  ? 706 ARG A NH1 1 
ATOM   4752  N NH2 . ARG A 1 706 ? 100.393 101.451 113.518 1.00 39.62  ? 706 ARG A NH2 1 
ATOM   4753  N N   . VAL A 1 707 ? 106.333 105.398 114.299 1.00 29.09  ? 707 VAL A N   1 
ATOM   4754  C CA  . VAL A 1 707 ? 106.775 106.704 114.792 1.00 27.48  ? 707 VAL A CA  1 
ATOM   4755  C C   . VAL A 1 707 ? 106.177 107.788 113.900 1.00 32.06  ? 707 VAL A C   1 
ATOM   4756  O O   . VAL A 1 707 ? 106.196 107.681 112.678 1.00 36.12  ? 707 VAL A O   1 
ATOM   4757  C CB  . VAL A 1 707 ? 108.309 106.793 114.846 1.00 32.19  ? 707 VAL A CB  1 
ATOM   4758  C CG1 . VAL A 1 707 ? 108.789 108.128 115.416 1.00 25.98  ? 707 VAL A CG1 1 
ATOM   4759  C CG2 . VAL A 1 707 ? 108.937 105.686 115.696 1.00 32.26  ? 707 VAL A CG2 1 
ATOM   4760  N N   . GLU A 1 708 ? 105.632 108.832 114.508 1.00 40.98  ? 708 GLU A N   1 
ATOM   4761  C CA  . GLU A 1 708 ? 105.076 109.981 113.805 1.00 31.70  ? 708 GLU A CA  1 
ATOM   4762  C C   . GLU A 1 708 ? 105.992 111.174 114.073 1.00 36.03  ? 708 GLU A C   1 
ATOM   4763  O O   . GLU A 1 708 ? 106.131 111.620 115.209 1.00 45.02  ? 708 GLU A O   1 
ATOM   4764  C CB  . GLU A 1 708 ? 103.639 110.255 114.284 1.00 35.70  ? 708 GLU A CB  1 
ATOM   4765  C CG  . GLU A 1 708 ? 102.731 109.015 114.299 1.00 37.57  ? 708 GLU A CG  1 
ATOM   4766  C CD  . GLU A 1 708 ? 101.333 109.290 114.871 1.00 46.39  ? 708 GLU A CD  1 
ATOM   4767  O OE1 . GLU A 1 708 ? 101.180 110.198 115.719 1.00 48.97  ? 708 GLU A OE1 1 
ATOM   4768  O OE2 . GLU A 1 708 ? 100.385 108.553 114.516 1.00 47.67  ? 708 GLU A OE2 1 
ATOM   4769  N N   . GLU A 1 709 ? 106.640 111.693 113.040 1.00 41.77  ? 709 GLU A N   1 
ATOM   4770  C CA  . GLU A 1 709 ? 107.490 112.878 113.117 1.00 40.39  ? 709 GLU A CA  1 
ATOM   4771  C C   . GLU A 1 709 ? 106.711 114.056 112.543 1.00 43.47  ? 709 GLU A C   1 
ATOM   4772  O O   . GLU A 1 709 ? 106.212 113.981 111.423 1.00 42.80  ? 709 GLU A O   1 
ATOM   4773  C CB  . GLU A 1 709 ? 108.809 112.646 112.355 1.00 41.51  ? 709 GLU A CB  1 
ATOM   4774  C CG  . GLU A 1 709 ? 109.698 113.903 112.332 1.00 45.40  ? 709 GLU A CG  1 
ATOM   4775  C CD  . GLU A 1 709 ? 110.991 113.779 111.506 1.00 51.18  ? 709 GLU A CD  1 
ATOM   4776  O OE1 . GLU A 1 709 ? 111.145 112.826 110.710 1.00 51.45  ? 709 GLU A OE1 1 
ATOM   4777  O OE2 . GLU A 1 709 ? 111.850 114.686 111.620 1.00 48.74  ? 709 GLU A OE2 1 
ATOM   4778  N N   . VAL A 1 710 ? 106.646 115.166 113.278 1.00 43.86  ? 710 VAL A N   1 
ATOM   4779  C CA  . VAL A 1 710 ? 106.224 116.458 112.739 1.00 40.85  ? 710 VAL A CA  1 
ATOM   4780  C C   . VAL A 1 710 ? 107.447 117.361 112.681 1.00 37.06  ? 710 VAL A C   1 
ATOM   4781  O O   . VAL A 1 710 ? 108.105 117.575 113.696 1.00 42.17  ? 710 VAL A O   1 
ATOM   4782  C CB  . VAL A 1 710 ? 105.094 117.098 113.558 1.00 39.94  ? 710 VAL A CB  1 
ATOM   4783  C CG1 . VAL A 1 710 ? 104.548 118.324 112.824 1.00 39.21  ? 710 VAL A CG1 1 
ATOM   4784  C CG2 . VAL A 1 710 ? 103.949 116.117 113.821 1.00 39.17  ? 710 VAL A CG2 1 
ATOM   4785  N N   . ASN A 1 711 ? 107.782 117.882 111.505 1.00 39.11  ? 711 ASN A N   1 
ATOM   4786  C CA  . ASN A 1 711 ? 108.994 118.672 111.301 1.00 37.09  ? 711 ASN A CA  1 
ATOM   4787  C C   . ASN A 1 711 ? 108.770 119.740 110.222 1.00 40.16  ? 711 ASN A C   1 
ATOM   4788  O O   . ASN A 1 711 ? 109.082 119.547 109.051 1.00 47.70  ? 711 ASN A O   1 
ATOM   4789  C CB  . ASN A 1 711 ? 110.147 117.702 111.000 1.00 40.55  ? 711 ASN A CB  1 
ATOM   4790  C CG  . ASN A 1 711 ? 111.519 118.332 111.131 1.00 43.15  ? 711 ASN A CG  1 
ATOM   4791  O OD1 . ASN A 1 711 ? 111.697 119.538 111.060 1.00 43.03  ? 711 ASN A OD1 1 
ATOM   4792  N ND2 . ASN A 1 711 ? 112.525 117.520 111.340 1.00 45.57  ? 711 ASN A ND2 1 
ATOM   4793  N N   . TRP A 1 712 ? 108.210 120.878 110.627 1.00 37.99  ? 712 TRP A N   1 
ATOM   4794  C CA  . TRP A 1 712 ? 107.938 122.026 109.761 1.00 37.64  ? 712 TRP A CA  1 
ATOM   4795  C C   . TRP A 1 712 ? 109.200 122.614 109.139 1.00 39.17  ? 712 TRP A C   1 
ATOM   4796  O O   . TRP A 1 712 ? 109.215 122.897 107.947 1.00 42.13  ? 712 TRP A O   1 
ATOM   4797  C CB  . TRP A 1 712 ? 107.231 123.108 110.581 1.00 41.29  ? 712 TRP A CB  1 
ATOM   4798  C CG  . TRP A 1 712 ? 105.819 122.821 110.960 1.00 39.45  ? 712 TRP A CG  1 
ATOM   4799  C CD1 . TRP A 1 712 ? 105.408 122.114 112.032 1.00 41.04  ? 712 TRP A CD1 1 
ATOM   4800  C CD2 . TRP A 1 712 ? 104.604 123.270 110.285 1.00 38.26  ? 712 TRP A CD2 1 
ATOM   4801  N NE1 . TRP A 1 712 ? 104.030 122.081 112.065 1.00 42.60  ? 712 TRP A NE1 1 
ATOM   4802  C CE2 . TRP A 1 712 ? 103.485 122.806 111.034 1.00 41.39  ? 712 TRP A CE2 1 
ATOM   4803  C CE3 . TRP A 1 712 ? 104.343 124.067 109.155 1.00 34.27  ? 712 TRP A CE3 1 
ATOM   4804  C CZ2 . TRP A 1 712 ? 102.169 123.123 110.678 1.00 40.61  ? 712 TRP A CZ2 1 
ATOM   4805  C CZ3 . TRP A 1 712 ? 103.023 124.393 108.791 1.00 34.62  ? 712 TRP A CZ3 1 
ATOM   4806  C CH2 . TRP A 1 712 ? 101.942 123.927 109.556 1.00 39.78  ? 712 TRP A CH2 1 
ATOM   4807  N N   . ALA A 1 713 ? 110.269 122.758 109.917 1.00 44.85  ? 713 ALA A N   1 
ATOM   4808  C CA  . ALA A 1 713 ? 111.524 123.329 109.446 1.00 43.61  ? 713 ALA A CA  1 
ATOM   4809  C C   . ALA A 1 713 ? 112.170 122.486 108.335 1.00 45.88  ? 713 ALA A C   1 
ATOM   4810  O O   . ALA A 1 713 ? 112.613 123.035 107.332 1.00 49.51  ? 713 ALA A O   1 
ATOM   4811  C CB  . ALA A 1 713 ? 112.453 123.506 110.650 1.00 43.41  ? 713 ALA A CB  1 
ATOM   4812  N N   . ALA A 1 714 ? 112.186 121.156 108.465 1.00 44.29  ? 714 ALA A N   1 
ATOM   4813  C CA  . ALA A 1 714 ? 112.665 120.277 107.407 1.00 40.89  ? 714 ALA A CA  1 
ATOM   4814  C C   . ALA A 1 714 ? 111.728 120.254 106.192 1.00 44.56  ? 714 ALA A C   1 
ATOM   4815  O O   . ALA A 1 714 ? 112.195 120.220 105.057 1.00 48.15  ? 714 ALA A O   1 
ATOM   4816  C CB  . ALA A 1 714 ? 112.858 118.871 107.974 1.00 42.47  ? 714 ALA A CB  1 
ATOM   4817  N N   . TRP A 1 715 ? 110.413 120.294 106.406 1.00 41.71  ? 715 TRP A N   1 
ATOM   4818  C CA  . TRP A 1 715 ? 109.425 120.257 105.330 1.00 42.93  ? 715 TRP A CA  1 
ATOM   4819  C C   . TRP A 1 715 ? 109.423 121.521 104.472 1.00 42.69  ? 715 TRP A C   1 
ATOM   4820  O O   . TRP A 1 715 ? 109.508 121.420 103.252 1.00 46.29  ? 715 TRP A O   1 
ATOM   4821  C CB  . TRP A 1 715 ? 108.049 119.976 105.926 1.00 38.51  ? 715 TRP A CB  1 
ATOM   4822  C CG  . TRP A 1 715 ? 106.905 120.119 104.979 1.00 38.24  ? 715 TRP A CG  1 
ATOM   4823  C CD1 . TRP A 1 715 ? 106.660 119.330 103.915 1.00 36.87  ? 715 TRP A CD1 1 
ATOM   4824  C CD2 . TRP A 1 715 ? 105.851 121.123 104.983 1.00 41.69  ? 715 TRP A CD2 1 
ATOM   4825  N NE1 . TRP A 1 715 ? 105.514 119.758 103.277 1.00 40.10  ? 715 TRP A NE1 1 
ATOM   4826  C CE2 . TRP A 1 715 ? 104.959 120.848 103.910 1.00 39.79  ? 715 TRP A CE2 1 
ATOM   4827  C CE3 . TRP A 1 715 ? 105.543 122.224 105.807 1.00 34.42  ? 715 TRP A CE3 1 
ATOM   4828  C CZ2 . TRP A 1 715 ? 103.804 121.601 103.675 1.00 38.79  ? 715 TRP A CZ2 1 
ATOM   4829  C CZ3 . TRP A 1 715 ? 104.392 122.990 105.581 1.00 38.19  ? 715 TRP A CZ3 1 
ATOM   4830  C CH2 . TRP A 1 715 ? 103.517 122.678 104.529 1.00 38.69  ? 715 TRP A CH2 1 
ATOM   4831  N N   . GLU A 1 716 ? 109.407 122.714 105.067 1.00 49.29  ? 716 GLU A N   1 
ATOM   4832  C CA  . GLU A 1 716 ? 109.361 123.974 104.315 1.00 51.15  ? 716 GLU A CA  1 
ATOM   4833  C C   . GLU A 1 716 ? 110.560 124.171 103.378 1.00 55.42  ? 716 GLU A C   1 
ATOM   4834  O O   . GLU A 1 716 ? 110.411 124.701 102.280 1.00 58.35  ? 716 GLU A O   1 
ATOM   4835  C CB  . GLU A 1 716 ? 109.254 125.160 105.276 1.00 50.87  ? 716 GLU A CB  1 
ATOM   4836  C CG  . GLU A 1 716 ? 107.842 125.283 105.857 1.00 56.54  ? 716 GLU A CG  1 
ATOM   4837  C CD  . GLU A 1 716 ? 107.613 126.652 106.511 1.00 57.04  ? 716 GLU A CD  1 
ATOM   4838  O OE1 . GLU A 1 716 ? 108.520 127.145 107.213 1.00 55.54  ? 716 GLU A OE1 1 
ATOM   4839  O OE2 . GLU A 1 716 ? 106.533 127.242 106.284 1.00 56.04  ? 716 GLU A OE2 1 
ATOM   4840  N N   . LYS A 1 717 ? 111.738 123.658 103.753 1.00 52.19  ? 717 LYS A N   1 
ATOM   4841  C CA  . LYS A 1 717 ? 112.942 123.662 102.908 1.00 51.99  ? 717 LYS A CA  1 
ATOM   4842  C C   . LYS A 1 717 ? 112.801 122.826 101.632 1.00 54.51  ? 717 LYS A C   1 
ATOM   4843  O O   . LYS A 1 717 ? 113.544 123.060 100.682 1.00 59.27  ? 717 LYS A O   1 
ATOM   4844  C CB  . LYS A 1 717 ? 114.142 123.191 103.740 1.00 52.36  ? 717 LYS A CB  1 
ATOM   4845  C CG  . LYS A 1 717 ? 114.509 124.226 104.814 1.00 55.04  ? 717 LYS A CG  1 
ATOM   4846  C CD  . LYS A 1 717 ? 115.601 123.701 105.750 1.00 56.54  ? 717 LYS A CD  1 
ATOM   4847  C CE  . LYS A 1 717 ? 115.811 124.700 106.891 1.00 56.49  ? 717 LYS A CE  1 
ATOM   4848  N NZ  . LYS A 1 717 ? 116.873 124.257 107.822 1.00 55.74  ? 717 LYS A NZ  1 
ATOM   4849  N N   . THR A 1 718 ? 111.852 121.893 101.569 1.00 49.56  ? 718 THR A N   1 
ATOM   4850  C CA  . THR A 1 718 ? 111.573 121.078 100.369 1.00 50.56  ? 718 THR A CA  1 
ATOM   4851  C C   . THR A 1 718 ? 110.648 121.759 99.355  1.00 52.71  ? 718 THR A C   1 
ATOM   4852  O O   . THR A 1 718 ? 110.557 121.305 98.213  1.00 54.89  ? 718 THR A O   1 
ATOM   4853  C CB  . THR A 1 718 ? 110.986 119.698 100.711 1.00 54.54  ? 718 THR A CB  1 
ATOM   4854  O OG1 . THR A 1 718 ? 109.654 119.771 101.165 1.00 53.65  ? 718 THR A OG1 1 
ATOM   4855  C CG2 . THR A 1 718 ? 111.804 118.952 101.760 1.00 53.69  ? 718 THR A CG2 1 
ATOM   4856  N N   . LEU A 1 719 ? 109.945 122.827 99.733  1.00 49.98  ? 719 LEU A N   1 
ATOM   4857  C CA  . LEU A 1 719 ? 108.911 123.446 98.900  1.00 52.53  ? 719 LEU A CA  1 
ATOM   4858  C C   . LEU A 1 719 ? 109.528 124.281 97.772  1.00 55.35  ? 719 LEU A C   1 
ATOM   4859  O O   . LEU A 1 719 ? 108.955 124.396 96.686  1.00 54.07  ? 719 LEU A O   1 
ATOM   4860  C CB  . LEU A 1 719 ? 107.952 124.279 99.777  1.00 54.46  ? 719 LEU A CB  1 
ATOM   4861  C CG  . LEU A 1 719 ? 107.327 123.520 100.964 1.00 52.49  ? 719 LEU A CG  1 
ATOM   4862  C CD1 . LEU A 1 719 ? 106.359 124.435 101.710 1.00 50.33  ? 719 LEU A CD1 1 
ATOM   4863  C CD2 . LEU A 1 719 ? 106.585 122.260 100.540 1.00 48.63  ? 719 LEU A CD2 1 
ATOM   4864  N N   . ARG B 1 74  ? 80.327  90.955  88.724  1.00 118.61 ? 74  ARG B N   1 
ATOM   4865  C CA  . ARG B 1 74  ? 80.211  92.023  89.755  1.00 119.70 ? 74  ARG B CA  1 
ATOM   4866  C C   . ARG B 1 74  ? 81.472  92.888  89.758  1.00 119.77 ? 74  ARG B C   1 
ATOM   4867  O O   . ARG B 1 74  ? 82.334  92.681  88.878  1.00 119.17 ? 74  ARG B O   1 
ATOM   4868  C CB  . ARG B 1 74  ? 80.000  91.418  91.146  1.00 119.43 ? 74  ARG B CB  1 
ATOM   4869  C CG  . ARG B 1 74  ? 81.268  90.892  91.803  1.00 118.70 ? 74  ARG B CG  1 
ATOM   4870  C CD  . ARG B 1 74  ? 80.962  89.907  92.913  1.00 118.82 ? 74  ARG B CD  1 
ATOM   4871  N NE  . ARG B 1 74  ? 79.942  90.384  93.835  1.00 119.66 ? 74  ARG B NE  1 
ATOM   4872  C CZ  . ARG B 1 74  ? 80.192  91.017  94.975  1.00 119.51 ? 74  ARG B CZ  1 
ATOM   4873  N NH1 . ARG B 1 74  ? 79.192  91.411  95.747  1.00 119.04 ? 74  ARG B NH1 1 
ATOM   4874  N NH2 . ARG B 1 74  ? 81.439  91.253  95.343  1.00 118.94 ? 74  ARG B NH2 1 
ATOM   4875  N N   . PHE B 1 75  ? 81.573  93.804  90.725  1.00 116.99 ? 75  PHE B N   1 
ATOM   4876  C CA  . PHE B 1 75  ? 82.738  94.698  90.828  1.00 116.91 ? 75  PHE B CA  1 
ATOM   4877  C C   . PHE B 1 75  ? 82.890  95.179  92.281  1.00 116.45 ? 75  PHE B C   1 
ATOM   4878  O O   . PHE B 1 75  ? 81.922  95.612  92.899  1.00 115.50 ? 75  PHE B O   1 
ATOM   4879  C CB  . PHE B 1 75  ? 82.600  95.871  89.846  1.00 116.08 ? 75  PHE B CB  1 
ATOM   4880  C CG  . PHE B 1 75  ? 83.923  96.398  89.317  1.00 115.97 ? 75  PHE B CG  1 
ATOM   4881  C CD1 . PHE B 1 75  ? 84.889  96.955  90.176  1.00 115.54 ? 75  PHE B CD1 1 
ATOM   4882  C CD2 . PHE B 1 75  ? 84.182  96.341  87.936  1.00 115.49 ? 75  PHE B CD2 1 
ATOM   4883  C CE1 . PHE B 1 75  ? 86.092  97.461  89.659  1.00 115.90 ? 75  PHE B CE1 1 
ATOM   4884  C CE2 . PHE B 1 75  ? 85.370  96.875  87.417  1.00 115.28 ? 75  PHE B CE2 1 
ATOM   4885  C CZ  . PHE B 1 75  ? 86.329  97.437  88.278  1.00 115.32 ? 75  PHE B CZ  1 
ATOM   4886  N N   . ASP B 1 76  ? 84.090  95.098  92.850  1.00 114.73 ? 76  ASP B N   1 
ATOM   4887  C CA  . ASP B 1 76  ? 84.283  95.158  94.304  1.00 114.26 ? 76  ASP B CA  1 
ATOM   4888  C C   . ASP B 1 76  ? 85.520  95.982  94.705  1.00 115.33 ? 76  ASP B C   1 
ATOM   4889  O O   . ASP B 1 76  ? 86.413  96.227  93.895  1.00 114.72 ? 76  ASP B O   1 
ATOM   4890  C CB  . ASP B 1 76  ? 84.333  93.714  94.836  1.00 113.94 ? 76  ASP B CB  1 
ATOM   4891  C CG  . ASP B 1 76  ? 83.778  93.560  96.255  1.00 115.37 ? 76  ASP B CG  1 
ATOM   4892  O OD1 . ASP B 1 76  ? 83.709  94.564  96.997  1.00 115.09 ? 76  ASP B OD1 1 
ATOM   4893  O OD2 . ASP B 1 76  ? 83.395  92.423  96.606  1.00 115.34 ? 76  ASP B OD2 1 
ATOM   4894  N N   . ARG B 1 77  ? 85.557  96.426  95.967  1.00 109.43 ? 77  ARG B N   1 
ATOM   4895  C CA  . ARG B 1 77  ? 86.511  97.415  96.498  1.00 107.82 ? 77  ARG B CA  1 
ATOM   4896  C C   . ARG B 1 77  ? 87.974  97.041  96.272  1.00 107.81 ? 77  ARG B C   1 
ATOM   4897  O O   . ARG B 1 77  ? 88.742  97.864  95.784  1.00 108.19 ? 77  ARG B O   1 
ATOM   4898  C CB  . ARG B 1 77  ? 86.194  97.649  97.986  1.00 107.25 ? 77  ARG B CB  1 
ATOM   4899  C CG  . ARG B 1 77  ? 87.308  98.391  98.734  1.00 107.65 ? 77  ARG B CG  1 
ATOM   4900  C CD  . ARG B 1 77  ? 86.857  99.019  100.054 1.00 107.52 ? 77  ARG B CD  1 
ATOM   4901  N NE  . ARG B 1 77  ? 86.064  98.113  100.902 1.00 108.01 ? 77  ARG B NE  1 
ATOM   4902  C CZ  . ARG B 1 77  ? 86.443  97.495  102.004 1.00 108.37 ? 77  ARG B CZ  1 
ATOM   4903  N NH1 . ARG B 1 77  ? 85.566  96.871  102.729 1.00 108.42 ? 77  ARG B NH1 1 
ATOM   4904  N NH2 . ARG B 1 77  ? 87.679  97.464  102.401 1.00 107.36 ? 77  ARG B NH2 1 
ATOM   4905  N N   . ASP B 1 78  ? 88.362  95.810  96.590  1.00 109.09 ? 78  ASP B N   1 
ATOM   4906  C CA  . ASP B 1 78  ? 89.757  95.364  96.489  1.00 109.11 ? 78  ASP B CA  1 
ATOM   4907  C C   . ASP B 1 78  ? 90.262  95.292  95.036  1.00 108.60 ? 78  ASP B C   1 
ATOM   4908  O O   . ASP B 1 78  ? 91.439  95.534  94.781  1.00 107.75 ? 78  ASP B O   1 
ATOM   4909  C CB  . ASP B 1 78  ? 89.921  94.018  97.208  1.00 109.08 ? 78  ASP B CB  1 
ATOM   4910  C CG  . ASP B 1 78  ? 89.547  94.077  98.696  1.00 108.73 ? 78  ASP B CG  1 
ATOM   4911  O OD1 . ASP B 1 78  ? 89.730  95.133  99.334  1.00 108.59 ? 78  ASP B OD1 1 
ATOM   4912  O OD2 . ASP B 1 78  ? 89.079  93.051  99.231  1.00 108.76 ? 78  ASP B OD2 1 
ATOM   4913  N N   . ARG B 1 79  ? 89.370  95.029  94.069  1.00 111.67 ? 79  ARG B N   1 
ATOM   4914  C CA  . ARG B 1 79  ? 89.657  95.195  92.634  1.00 113.14 ? 79  ARG B CA  1 
ATOM   4915  C C   . ARG B 1 79  ? 89.780  96.675  92.304  1.00 113.16 ? 79  ARG B C   1 
ATOM   4916  O O   . ARG B 1 79  ? 90.813  97.110  91.796  1.00 112.36 ? 79  ARG B O   1 
ATOM   4917  C CB  . ARG B 1 79  ? 88.572  94.492  91.790  1.00 113.00 ? 79  ARG B CB  1 
ATOM   4918  C CG  . ARG B 1 79  ? 88.719  94.712  90.277  1.00 112.19 ? 79  ARG B CG  1 
ATOM   4919  C CD  . ARG B 1 79  ? 87.608  93.989  89.502  1.00 111.84 ? 79  ARG B CD  1 
ATOM   4920  N NE  . ARG B 1 79  ? 87.538  94.445  88.099  1.00 113.72 ? 79  ARG B NE  1 
ATOM   4921  C CZ  . ARG B 1 79  ? 87.607  93.717  87.002  1.00 113.09 ? 79  ARG B CZ  1 
ATOM   4922  N NH1 . ARG B 1 79  ? 87.536  94.278  85.833  1.00 112.24 ? 79  ARG B NH1 1 
ATOM   4923  N NH2 . ARG B 1 79  ? 87.735  92.426  87.034  1.00 112.29 ? 79  ARG B NH2 1 
ATOM   4924  N N   . LEU B 1 80  ? 88.764  97.476  92.637  1.00 109.89 ? 80  LEU B N   1 
ATOM   4925  C CA  . LEU B 1 80  ? 88.681  98.903  92.306  1.00 108.95 ? 80  LEU B CA  1 
ATOM   4926  C C   . LEU B 1 80  ? 89.885  99.712  92.806  1.00 108.06 ? 80  LEU B C   1 
ATOM   4927  O O   . LEU B 1 80  ? 90.521  100.423 92.032  1.00 108.57 ? 80  LEU B O   1 
ATOM   4928  C CB  . LEU B 1 80  ? 87.355  99.449  92.872  1.00 108.09 ? 80  LEU B CB  1 
ATOM   4929  C CG  . LEU B 1 80  ? 87.135  100.947 92.624  1.00 108.19 ? 80  LEU B CG  1 
ATOM   4930  C CD1 . LEU B 1 80  ? 87.145  101.288 91.139  1.00 108.96 ? 80  LEU B CD1 1 
ATOM   4931  C CD2 . LEU B 1 80  ? 85.792  101.359 93.208  1.00 107.98 ? 80  LEU B CD2 1 
ATOM   4932  N N   . PHE B 1 81  ? 90.246  99.569  94.080  1.00 101.81 ? 81  PHE B N   1 
ATOM   4933  C CA  . PHE B 1 81  ? 91.419  100.224 94.671  1.00 101.83 ? 81  PHE B CA  1 
ATOM   4934  C C   . PHE B 1 81  ? 92.739  99.827  93.991  1.00 103.63 ? 81  PHE B C   1 
ATOM   4935  O O   . PHE B 1 81  ? 93.704  100.592 94.024  1.00 102.72 ? 81  PHE B O   1 
ATOM   4936  C CB  . PHE B 1 81  ? 91.483  99.877  96.160  1.00 100.91 ? 81  PHE B CB  1 
ATOM   4937  C CG  . PHE B 1 81  ? 90.459  100.529 97.071  1.00 102.04 ? 81  PHE B CG  1 
ATOM   4938  C CD1 . PHE B 1 81  ? 89.495  101.452 96.610  1.00 101.54 ? 81  PHE B CD1 1 
ATOM   4939  C CD2 . PHE B 1 81  ? 90.521  100.228 98.443  1.00 102.30 ? 81  PHE B CD2 1 
ATOM   4940  C CE1 . PHE B 1 81  ? 88.625  102.074 97.520  1.00 101.23 ? 81  PHE B CE1 1 
ATOM   4941  C CE2 . PHE B 1 81  ? 89.652  100.856 99.349  1.00 101.18 ? 81  PHE B CE2 1 
ATOM   4942  C CZ  . PHE B 1 81  ? 88.713  101.790 98.890  1.00 101.26 ? 81  PHE B CZ  1 
ATOM   4943  N N   . SER B 1 82  ? 92.797  98.659  93.350  1.00 107.93 ? 82  SER B N   1 
ATOM   4944  C CA  . SER B 1 82  ? 93.965  98.254  92.564  1.00 107.33 ? 82  SER B CA  1 
ATOM   4945  C C   . SER B 1 82  ? 93.973  98.928  91.185  1.00 106.80 ? 82  SER B C   1 
ATOM   4946  O O   . SER B 1 82  ? 95.011  99.422  90.747  1.00 106.41 ? 82  SER B O   1 
ATOM   4947  C CB  . SER B 1 82  ? 93.991  96.725  92.451  1.00 107.69 ? 82  SER B CB  1 
ATOM   4948  O OG  . SER B 1 82  ? 95.245  96.259  91.992  1.00 107.59 ? 82  SER B OG  1 
ATOM   4949  N N   . VAL B 1 83  ? 92.798  99.070  90.557  1.00 105.97 ? 83  VAL B N   1 
ATOM   4950  C CA  . VAL B 1 83  ? 92.628  99.795  89.285  1.00 106.99 ? 83  VAL B CA  1 
ATOM   4951  C C   . VAL B 1 83  ? 92.953  101.284 89.420  1.00 107.18 ? 83  VAL B C   1 
ATOM   4952  O O   . VAL B 1 83  ? 93.701  101.807 88.602  1.00 106.68 ? 83  VAL B O   1 
ATOM   4953  C CB  . VAL B 1 83  ? 91.208  99.625  88.710  1.00 107.33 ? 83  VAL B CB  1 
ATOM   4954  C CG1 . VAL B 1 83  ? 91.049  100.354 87.370  1.00 107.66 ? 83  VAL B CG1 1 
ATOM   4955  C CG2 . VAL B 1 83  ? 90.884  98.154  88.467  1.00 107.11 ? 83  VAL B CG2 1 
ATOM   4956  N N   . VAL B 1 84  ? 92.457  101.981 90.452  1.00 100.60 ? 84  VAL B N   1 
ATOM   4957  C CA  . VAL B 1 84  ? 92.676  103.438 90.579  1.00 99.16  ? 84  VAL B CA  1 
ATOM   4958  C C   . VAL B 1 84  ? 94.143  103.847 90.766  1.00 98.71  ? 84  VAL B C   1 
ATOM   4959  O O   . VAL B 1 84  ? 94.476  105.009 90.560  1.00 98.07  ? 84  VAL B O   1 
ATOM   4960  C CB  . VAL B 1 84  ? 91.803  104.092 91.663  1.00 97.82  ? 84  VAL B CB  1 
ATOM   4961  C CG1 . VAL B 1 84  ? 90.317  103.798 91.480  1.00 97.74  ? 84  VAL B CG1 1 
ATOM   4962  C CG2 . VAL B 1 84  ? 92.212  103.715 93.083  1.00 97.36  ? 84  VAL B CG2 1 
ATOM   4963  N N   . SER B 1 85  ? 95.036  102.923 91.127  1.00 102.32 ? 85  SER B N   1 
ATOM   4964  C CA  . SER B 1 85  ? 96.486  103.156 91.187  1.00 102.53 ? 85  SER B CA  1 
ATOM   4965  C C   . SER B 1 85  ? 97.225  102.859 89.860  1.00 103.46 ? 85  SER B C   1 
ATOM   4966  O O   . SER B 1 85  ? 98.369  103.284 89.681  1.00 102.75 ? 85  SER B O   1 
ATOM   4967  C CB  . SER B 1 85  ? 97.058  102.342 92.355  1.00 101.12 ? 85  SER B CB  1 
ATOM   4968  O OG  . SER B 1 85  ? 98.419  102.639 92.583  1.00 101.53 ? 85  SER B OG  1 
ATOM   4969  N N   . ARG B 1 86  ? 96.545  102.215 88.893  1.00 109.96 ? 86  ARG B N   1 
ATOM   4970  C CA  . ARG B 1 86  ? 97.170  101.874 87.572  1.00 111.01 ? 86  ARG B CA  1 
ATOM   4971  C C   . ARG B 1 86  ? 96.986  103.003 86.558  1.00 112.11 ? 86  ARG B C   1 
ATOM   4972  O O   . ARG B 1 86  ? 96.013  103.770 86.691  1.00 110.05 ? 86  ARG B O   1 
ATOM   4973  C CB  . ARG B 1 86  ? 96.605  100.555 87.000  1.00 111.50 ? 86  ARG B CB  1 
ATOM   4974  C CG  . ARG B 1 86  ? 97.340  99.342  87.578  1.00 110.38 ? 86  ARG B CG  1 
ATOM   4975  C CD  . ARG B 1 86  ? 96.826  98.024  87.029  1.00 110.85 ? 86  ARG B CD  1 
ATOM   4976  N NE  . ARG B 1 86  ? 95.456  97.727  87.424  1.00 111.18 ? 86  ARG B NE  1 
ATOM   4977  C CZ  . ARG B 1 86  ? 95.119  97.078  88.532  1.00 110.34 ? 86  ARG B CZ  1 
ATOM   4978  N NH1 . ARG B 1 86  ? 93.846  96.847  88.803  1.00 110.51 ? 86  ARG B NH1 1 
ATOM   4979  N NH2 . ARG B 1 86  ? 96.054  96.663  89.367  1.00 109.54 ? 86  ARG B NH2 1 
ATOM   4980  N N   . GLY B 1 87  ? 97.890  103.086 85.587  1.00 117.59 ? 87  GLY B N   1 
ATOM   4981  C CA  . GLY B 1 87  ? 97.872  104.078 84.504  1.00 116.19 ? 87  GLY B CA  1 
ATOM   4982  C C   . GLY B 1 87  ? 96.845  103.808 83.393  1.00 116.91 ? 87  GLY B C   1 
ATOM   4983  O O   . GLY B 1 87  ? 96.581  104.690 82.580  1.00 116.95 ? 87  GLY B O   1 
ATOM   4984  N N   . VAL B 1 88  ? 96.246  102.612 83.362  1.00 119.52 ? 88  VAL B N   1 
ATOM   4985  C CA  . VAL B 1 88  ? 95.152  102.247 82.444  1.00 120.18 ? 88  VAL B CA  1 
ATOM   4986  C C   . VAL B 1 88  ? 93.817  102.119 83.202  1.00 119.70 ? 88  VAL B C   1 
ATOM   4987  O O   . VAL B 1 88  ? 93.705  101.286 84.102  1.00 118.63 ? 88  VAL B O   1 
ATOM   4988  C CB  . VAL B 1 88  ? 95.465  100.962 81.647  1.00 119.64 ? 88  VAL B CB  1 
ATOM   4989  C CG1 . VAL B 1 88  ? 96.425  101.276 80.501  1.00 118.55 ? 88  VAL B CG1 1 
ATOM   4990  C CG2 . VAL B 1 88  ? 96.065  99.815  82.468  1.00 118.97 ? 88  VAL B CG2 1 
ATOM   4991  N N   . PRO B 1 89  ? 92.779  102.899 82.850  1.00 117.63 ? 89  PRO B N   1 
ATOM   4992  C CA  . PRO B 1 89  ? 91.469  102.840 83.503  1.00 117.44 ? 89  PRO B CA  1 
ATOM   4993  C C   . PRO B 1 89  ? 90.518  101.760 82.951  1.00 118.00 ? 89  PRO B C   1 
ATOM   4994  O O   . PRO B 1 89  ? 89.438  101.571 83.500  1.00 117.15 ? 89  PRO B O   1 
ATOM   4995  C CB  . PRO B 1 89  ? 90.882  104.233 83.295  1.00 115.87 ? 89  PRO B CB  1 
ATOM   4996  C CG  . PRO B 1 89  ? 91.432  104.643 81.932  1.00 115.67 ? 89  PRO B CG  1 
ATOM   4997  C CD  . PRO B 1 89  ? 92.831  104.035 81.937  1.00 115.86 ? 89  PRO B CD  1 
ATOM   4998  N N   . GLU B 1 90  ? 90.860  101.051 81.870  1.00 117.58 ? 90  GLU B N   1 
ATOM   4999  C CA  . GLU B 1 90  ? 89.905  100.170 81.177  1.00 117.59 ? 90  GLU B CA  1 
ATOM   5000  C C   . GLU B 1 90  ? 89.360  99.021  82.042  1.00 117.74 ? 90  GLU B C   1 
ATOM   5001  O O   . GLU B 1 90  ? 88.253  98.531  81.818  1.00 117.52 ? 90  GLU B O   1 
ATOM   5002  C CB  . GLU B 1 90  ? 90.566  99.595  79.911  1.00 117.25 ? 90  GLU B CB  1 
ATOM   5003  C CG  . GLU B 1 90  ? 91.140  100.644 78.941  1.00 117.18 ? 90  GLU B CG  1 
ATOM   5004  C CD  . GLU B 1 90  ? 90.118  101.650 78.386  1.00 117.73 ? 90  GLU B CD  1 
ATOM   5005  O OE1 . GLU B 1 90  ? 88.895  101.386 78.423  1.00 117.23 ? 90  GLU B OE1 1 
ATOM   5006  O OE2 . GLU B 1 90  ? 90.547  102.706 77.877  1.00 117.08 ? 90  GLU B OE2 1 
ATOM   5007  N N   . GLU B 1 91  ? 90.097  98.610  83.076  1.00 114.74 ? 91  GLU B N   1 
ATOM   5008  C CA  . GLU B 1 91  ? 89.676  97.569  84.024  1.00 115.05 ? 91  GLU B CA  1 
ATOM   5009  C C   . GLU B 1 91  ? 88.444  97.979  84.861  1.00 114.93 ? 91  GLU B C   1 
ATOM   5010  O O   . GLU B 1 91  ? 87.803  97.117  85.464  1.00 114.87 ? 91  GLU B O   1 
ATOM   5011  C CB  . GLU B 1 91  ? 90.897  97.162  84.868  1.00 114.36 ? 91  GLU B CB  1 
ATOM   5012  C CG  . GLU B 1 91  ? 90.682  95.881  85.691  1.00 114.52 ? 91  GLU B CG  1 
ATOM   5013  C CD  . GLU B 1 91  ? 91.969  95.309  86.314  1.00 114.80 ? 91  GLU B CD  1 
ATOM   5014  O OE1 . GLU B 1 91  ? 93.045  95.948  86.256  1.00 114.73 ? 91  GLU B OE1 1 
ATOM   5015  O OE2 . GLU B 1 91  ? 91.904  94.202  86.885  1.00 113.93 ? 91  GLU B OE2 1 
ATOM   5016  N N   . LEU B 1 92  ? 88.039  99.260  84.839  1.00 114.17 ? 92  LEU B N   1 
ATOM   5017  C CA  . LEU B 1 92  ? 86.756  99.744  85.368  1.00 114.97 ? 92  LEU B CA  1 
ATOM   5018  C C   . LEU B 1 92  ? 85.528  99.226  84.592  1.00 114.75 ? 92  LEU B C   1 
ATOM   5019  O O   . LEU B 1 92  ? 84.406  99.354  85.078  1.00 114.30 ? 92  LEU B O   1 
ATOM   5020  C CB  . LEU B 1 92  ? 86.717  101.286 85.358  1.00 115.20 ? 92  LEU B CB  1 
ATOM   5021  C CG  . LEU B 1 92  ? 87.747  102.016 86.235  1.00 115.12 ? 92  LEU B CG  1 
ATOM   5022  C CD1 . LEU B 1 92  ? 87.609  103.509 85.989  1.00 113.63 ? 92  LEU B CD1 1 
ATOM   5023  C CD2 . LEU B 1 92  ? 87.552  101.760 87.726  1.00 113.56 ? 92  LEU B CD2 1 
ATOM   5024  N N   . THR B 1 93  ? 85.693  98.673  83.387  1.00 116.02 ? 93  THR B N   1 
ATOM   5025  C CA  . THR B 1 93  ? 84.560  98.168  82.584  1.00 115.27 ? 93  THR B CA  1 
ATOM   5026  C C   . THR B 1 93  ? 83.751  97.106  83.341  1.00 116.21 ? 93  THR B C   1 
ATOM   5027  O O   . THR B 1 93  ? 84.302  96.154  83.893  1.00 116.61 ? 93  THR B O   1 
ATOM   5028  C CB  . THR B 1 93  ? 85.016  97.640  81.216  1.00 114.55 ? 93  THR B CB  1 
ATOM   5029  O OG1 . THR B 1 93  ? 86.176  96.844  81.304  1.00 114.62 ? 93  THR B OG1 1 
ATOM   5030  C CG2 . THR B 1 93  ? 85.322  98.783  80.257  1.00 114.86 ? 93  THR B CG2 1 
ATOM   5031  N N   . GLY B 1 94  ? 82.429  97.290  83.405  1.00 116.70 ? 94  GLY B N   1 
ATOM   5032  C CA  . GLY B 1 94  ? 81.510  96.502  84.238  1.00 116.50 ? 94  GLY B CA  1 
ATOM   5033  C C   . GLY B 1 94  ? 81.106  97.165  85.565  1.00 117.33 ? 94  GLY B C   1 
ATOM   5034  O O   . GLY B 1 94  ? 80.114  96.749  86.170  1.00 117.01 ? 94  GLY B O   1 
ATOM   5035  N N   . LEU B 1 95  ? 81.842  98.179  86.046  1.00 117.26 ? 95  LEU B N   1 
ATOM   5036  C CA  . LEU B 1 95  ? 81.578  98.840  87.337  1.00 116.27 ? 95  LEU B CA  1 
ATOM   5037  C C   . LEU B 1 95  ? 80.247  99.607  87.345  1.00 115.86 ? 95  LEU B C   1 
ATOM   5038  O O   . LEU B 1 95  ? 79.452  99.426  88.263  1.00 115.25 ? 95  LEU B O   1 
ATOM   5039  C CB  . LEU B 1 95  ? 82.767  99.755  87.686  1.00 115.55 ? 95  LEU B CB  1 
ATOM   5040  C CG  . LEU B 1 95  ? 82.640  100.577 88.981  1.00 116.35 ? 95  LEU B CG  1 
ATOM   5041  C CD1 . LEU B 1 95  ? 82.458  99.721  90.231  1.00 115.36 ? 95  LEU B CD1 1 
ATOM   5042  C CD2 . LEU B 1 95  ? 83.917  101.389 89.158  1.00 115.43 ? 95  LEU B CD2 1 
ATOM   5043  N N   . LEU B 1 96  ? 79.989  100.417 86.319  1.00 116.63 ? 96  LEU B N   1 
ATOM   5044  C CA  . LEU B 1 96  ? 78.731  101.151 86.199  1.00 117.64 ? 96  LEU B CA  1 
ATOM   5045  C C   . LEU B 1 96  ? 77.531  100.193 86.117  1.00 118.75 ? 96  LEU B C   1 
ATOM   5046  O O   . LEU B 1 96  ? 76.527  100.413 86.791  1.00 118.59 ? 96  LEU B O   1 
ATOM   5047  C CB  . LEU B 1 96  ? 78.827  102.083 84.981  1.00 117.16 ? 96  LEU B CB  1 
ATOM   5048  C CG  . LEU B 1 96  ? 77.547  102.883 84.690  1.00 117.58 ? 96  LEU B CG  1 
ATOM   5049  C CD1 . LEU B 1 96  ? 77.152  103.800 85.846  1.00 116.49 ? 96  LEU B CD1 1 
ATOM   5050  C CD2 . LEU B 1 96  ? 77.772  103.729 83.441  1.00 116.98 ? 96  LEU B CD2 1 
ATOM   5051  N N   . GLU B 1 97  ? 77.640  99.101  85.354  1.00 118.70 ? 97  GLU B N   1 
ATOM   5052  C CA  . GLU B 1 97  ? 76.618  98.062  85.268  1.00 118.25 ? 97  GLU B CA  1 
ATOM   5053  C C   . GLU B 1 97  ? 76.348  97.414  86.634  1.00 118.29 ? 97  GLU B C   1 
ATOM   5054  O O   . GLU B 1 97  ? 75.191  97.291  87.037  1.00 117.53 ? 97  GLU B O   1 
ATOM   5055  C CB  . GLU B 1 97  ? 77.020  96.994  84.238  1.00 118.30 ? 97  GLU B CB  1 
ATOM   5056  C CG  . GLU B 1 97  ? 77.185  97.528  82.805  1.00 118.56 ? 97  GLU B CG  1 
ATOM   5057  C CD  . GLU B 1 97  ? 78.632  97.891  82.424  1.00 118.47 ? 97  GLU B CD  1 
ATOM   5058  O OE1 . GLU B 1 97  ? 79.336  98.545  83.225  1.00 117.38 ? 97  GLU B OE1 1 
ATOM   5059  O OE2 . GLU B 1 97  ? 79.056  97.526  81.309  1.00 118.49 ? 97  GLU B OE2 1 
ATOM   5060  N N   . TYR B 1 98  ? 77.391  97.053  87.385  1.00 119.30 ? 98  TYR B N   1 
ATOM   5061  C CA  . TYR B 1 98  ? 77.226  96.439  88.703  1.00 119.54 ? 98  TYR B CA  1 
ATOM   5062  C C   . TYR B 1 98  ? 76.664  97.410  89.752  1.00 119.53 ? 98  TYR B C   1 
ATOM   5063  O O   . TYR B 1 98  ? 75.739  97.057  90.482  1.00 119.13 ? 98  TYR B O   1 
ATOM   5064  C CB  . TYR B 1 98  ? 78.554  95.837  89.166  1.00 118.86 ? 98  TYR B CB  1 
ATOM   5065  C CG  . TYR B 1 98  ? 78.417  95.060  90.456  1.00 119.31 ? 98  TYR B CG  1 
ATOM   5066  C CD1 . TYR B 1 98  ? 77.664  93.873  90.482  1.00 119.44 ? 98  TYR B CD1 1 
ATOM   5067  C CD2 . TYR B 1 98  ? 79.004  95.536  91.641  1.00 119.34 ? 98  TYR B CD2 1 
ATOM   5068  C CE1 . TYR B 1 98  ? 77.503  93.159  91.685  1.00 119.27 ? 98  TYR B CE1 1 
ATOM   5069  C CE2 . TYR B 1 98  ? 78.853  94.818  92.844  1.00 119.27 ? 98  TYR B CE2 1 
ATOM   5070  C CZ  . TYR B 1 98  ? 78.101  93.627  92.868  1.00 119.24 ? 98  TYR B CZ  1 
ATOM   5071  O OH  . TYR B 1 98  ? 77.968  92.920  94.019  1.00 119.59 ? 98  TYR B OH  1 
ATOM   5072  N N   . LEU B 1 99  ? 77.165  98.647  89.800  1.00 118.21 ? 99  LEU B N   1 
ATOM   5073  C CA  . LEU B 1 99  ? 76.650  99.698  90.682  1.00 118.72 ? 99  LEU B CA  1 
ATOM   5074  C C   . LEU B 1 99  ? 75.173  100.004 90.395  1.00 118.30 ? 99  LEU B C   1 
ATOM   5075  O O   . LEU B 1 99  ? 74.345  99.981  91.306  1.00 117.34 ? 99  LEU B O   1 
ATOM   5076  C CB  . LEU B 1 99  ? 77.490  100.974 90.495  1.00 118.65 ? 99  LEU B CB  1 
ATOM   5077  C CG  . LEU B 1 99  ? 78.900  100.928 91.106  1.00 118.03 ? 99  LEU B CG  1 
ATOM   5078  C CD1 . LEU B 1 99  ? 79.668  102.169 90.653  1.00 116.65 ? 99  LEU B CD1 1 
ATOM   5079  C CD2 . LEU B 1 99  ? 78.887  100.912 92.632  1.00 117.05 ? 99  LEU B CD2 1 
ATOM   5080  N N   . ARG B 1 100 ? 74.832  100.265 89.129  1.00 119.31 ? 100 ARG B N   1 
ATOM   5081  C CA  . ARG B 1 100 ? 73.494  100.729 88.723  1.00 119.54 ? 100 ARG B CA  1 
ATOM   5082  C C   . ARG B 1 100 ? 72.448  99.608  88.677  1.00 119.57 ? 100 ARG B C   1 
ATOM   5083  O O   . ARG B 1 100 ? 71.269  99.879  88.893  1.00 118.82 ? 100 ARG B O   1 
ATOM   5084  C CB  . ARG B 1 100 ? 73.644  101.500 87.398  1.00 119.18 ? 100 ARG B CB  1 
ATOM   5085  C CG  . ARG B 1 100 ? 72.453  102.410 87.072  1.00 118.90 ? 100 ARG B CG  1 
ATOM   5086  C CD  . ARG B 1 100 ? 72.826  103.477 86.034  1.00 118.50 ? 100 ARG B CD  1 
ATOM   5087  N NE  . ARG B 1 100 ? 73.222  102.897 84.742  1.00 119.54 ? 100 ARG B NE  1 
ATOM   5088  C CZ  . ARG B 1 100 ? 73.693  103.548 83.695  1.00 119.45 ? 100 ARG B CZ  1 
ATOM   5089  N NH1 . ARG B 1 100 ? 73.948  102.913 82.591  1.00 118.72 ? 100 ARG B NH1 1 
ATOM   5090  N NH2 . ARG B 1 100 ? 73.929  104.827 83.711  1.00 118.79 ? 100 ARG B NH2 1 
ATOM   5091  N N   . TRP B 1 101 ? 72.855  98.351  88.476  1.00 122.09 ? 101 TRP B N   1 
ATOM   5092  C CA  . TRP B 1 101 ? 71.971  97.185  88.598  1.00 122.35 ? 101 TRP B CA  1 
ATOM   5093  C C   . TRP B 1 101 ? 71.732  96.737  90.049  1.00 122.56 ? 101 TRP B C   1 
ATOM   5094  O O   . TRP B 1 101 ? 70.668  96.193  90.350  1.00 122.61 ? 101 TRP B O   1 
ATOM   5095  C CB  . TRP B 1 101 ? 72.559  96.029  87.798  1.00 121.13 ? 101 TRP B CB  1 
ATOM   5096  N N   . ASN B 1 102 ? 72.682  96.970  90.965  1.00 121.10 ? 102 ASN B N   1 
ATOM   5097  C CA  . ASN B 1 102 ? 72.554  96.629  92.389  1.00 120.92 ? 102 ASN B CA  1 
ATOM   5098  C C   . ASN B 1 102 ? 72.164  97.832  93.283  1.00 121.31 ? 102 ASN B C   1 
ATOM   5099  O O   . ASN B 1 102 ? 72.137  97.701  94.504  1.00 120.65 ? 102 ASN B O   1 
ATOM   5100  C CB  . ASN B 1 102 ? 73.852  95.928  92.843  1.00 121.43 ? 102 ASN B CB  1 
ATOM   5101  C CG  . ASN B 1 102 ? 73.692  95.026  94.060  1.00 121.61 ? 102 ASN B CG  1 
ATOM   5102  O OD1 . ASN B 1 102 ? 74.448  95.087  95.017  1.00 121.74 ? 102 ASN B OD1 1 
ATOM   5103  N ND2 . ASN B 1 102 ? 72.727  94.142  94.069  1.00 120.82 ? 102 ASN B ND2 1 
ATOM   5104  N N   . SER B 1 103 ? 71.849  98.989  92.687  1.00 120.75 ? 103 SER B N   1 
ATOM   5105  C CA  . SER B 1 103 ? 71.419  100.227 93.366  1.00 120.64 ? 103 SER B CA  1 
ATOM   5106  C C   . SER B 1 103 ? 72.414  100.748 94.416  1.00 120.86 ? 103 SER B C   1 
ATOM   5107  O O   . SER B 1 103 ? 72.043  101.040 95.557  1.00 119.69 ? 103 SER B O   1 
ATOM   5108  C CB  . SER B 1 103 ? 69.989  100.095 93.916  1.00 120.25 ? 103 SER B CB  1 
ATOM   5109  O OG  . SER B 1 103 ? 69.088  99.769  92.875  1.00 120.01 ? 103 SER B OG  1 
ATOM   5110  N N   . LYS B 1 104 ? 73.694  100.846 94.030  1.00 118.71 ? 104 LYS B N   1 
ATOM   5111  C CA  . LYS B 1 104 ? 74.836  101.238 94.879  1.00 118.04 ? 104 LYS B CA  1 
ATOM   5112  C C   . LYS B 1 104 ? 75.695  102.323 94.228  1.00 118.00 ? 104 LYS B C   1 
ATOM   5113  O O   . LYS B 1 104 ? 75.653  102.508 93.014  1.00 117.40 ? 104 LYS B O   1 
ATOM   5114  C CB  . LYS B 1 104 ? 75.692  100.005 95.210  1.00 117.33 ? 104 LYS B CB  1 
ATOM   5115  C CG  . LYS B 1 104 ? 75.046  99.162  96.313  1.00 117.46 ? 104 LYS B CG  1 
ATOM   5116  C CD  . LYS B 1 104 ? 75.814  97.864  96.555  1.00 118.29 ? 104 LYS B CD  1 
ATOM   5117  C CE  . LYS B 1 104 ? 75.092  97.050  97.634  1.00 118.23 ? 104 LYS B CE  1 
ATOM   5118  N NZ  . LYS B 1 104 ? 75.548  95.645  97.658  1.00 116.88 ? 104 LYS B NZ  1 
ATOM   5119  N N   . TYR B 1 105 ? 76.492  103.021 95.032  1.00 113.16 ? 105 TYR B N   1 
ATOM   5120  C CA  . TYR B 1 105 ? 77.335  104.148 94.613  1.00 112.44 ? 105 TYR B CA  1 
ATOM   5121  C C   . TYR B 1 105 ? 78.745  104.080 95.220  1.00 111.33 ? 105 TYR B C   1 
ATOM   5122  O O   . TYR B 1 105 ? 78.948  103.522 96.297  1.00 110.97 ? 105 TYR B O   1 
ATOM   5123  C CB  . TYR B 1 105 ? 76.671  105.473 95.012  1.00 111.65 ? 105 TYR B CB  1 
ATOM   5124  C CG  . TYR B 1 105 ? 75.178  105.573 94.774  1.00 112.52 ? 105 TYR B CG  1 
ATOM   5125  C CD1 . TYR B 1 105 ? 74.669  105.608 93.463  1.00 112.11 ? 105 TYR B CD1 1 
ATOM   5126  C CD2 . TYR B 1 105 ? 74.294  105.626 95.866  1.00 111.75 ? 105 TYR B CD2 1 
ATOM   5127  C CE1 . TYR B 1 105 ? 73.283  105.706 93.251  1.00 111.96 ? 105 TYR B CE1 1 
ATOM   5128  C CE2 . TYR B 1 105 ? 72.909  105.731 95.656  1.00 112.68 ? 105 TYR B CE2 1 
ATOM   5129  C CZ  . TYR B 1 105 ? 72.399  105.768 94.342  1.00 112.53 ? 105 TYR B CZ  1 
ATOM   5130  O OH  . TYR B 1 105 ? 71.063  105.851 94.126  1.00 111.09 ? 105 TYR B OH  1 
ATOM   5131  N N   . LEU B 1 106 ? 79.727  104.723 94.584  1.00 104.46 ? 106 LEU B N   1 
ATOM   5132  C CA  . LEU B 1 106 ? 81.111  104.774 95.078  1.00 103.94 ? 106 LEU B CA  1 
ATOM   5133  C C   . LEU B 1 106 ? 81.279  105.524 96.417  1.00 104.37 ? 106 LEU B C   1 
ATOM   5134  O O   . LEU B 1 106 ? 82.282  105.334 97.099  1.00 104.37 ? 106 LEU B O   1 
ATOM   5135  C CB  . LEU B 1 106 ? 82.004  105.381 93.985  1.00 103.68 ? 106 LEU B CB  1 
ATOM   5136  C CG  . LEU B 1 106 ? 82.101  104.532 92.706  1.00 103.78 ? 106 LEU B CG  1 
ATOM   5137  C CD1 . LEU B 1 106 ? 82.958  105.232 91.656  1.00 103.65 ? 106 LEU B CD1 1 
ATOM   5138  C CD2 . LEU B 1 106 ? 82.715  103.166 93.001  1.00 104.92 ? 106 LEU B CD2 1 
ATOM   5139  N N   . THR B 1 107 ? 80.302  106.343 96.823  1.00 106.89 ? 107 THR B N   1 
ATOM   5140  C CA  . THR B 1 107 ? 80.252  106.994 98.148  1.00 106.88 ? 107 THR B CA  1 
ATOM   5141  C C   . THR B 1 107 ? 79.764  106.049 99.261  1.00 106.69 ? 107 THR B C   1 
ATOM   5142  O O   . THR B 1 107 ? 79.927  106.352 100.443 1.00 106.20 ? 107 THR B O   1 
ATOM   5143  C CB  . THR B 1 107 ? 79.381  108.268 98.092  1.00 107.43 ? 107 THR B CB  1 
ATOM   5144  O OG1 . THR B 1 107 ? 79.886  109.144 97.115  1.00 107.14 ? 107 THR B OG1 1 
ATOM   5145  C CG2 . THR B 1 107 ? 79.350  109.095 99.374  1.00 106.27 ? 107 THR B CG2 1 
ATOM   5146  N N   . ASP B 1 108 ? 79.168  104.899 98.931  1.00 110.99 ? 108 ASP B N   1 
ATOM   5147  C CA  . ASP B 1 108 ? 78.665  103.938 99.929  1.00 110.82 ? 108 ASP B CA  1 
ATOM   5148  C C   . ASP B 1 108 ? 79.804  103.268 100.710 1.00 110.07 ? 108 ASP B C   1 
ATOM   5149  O O   . ASP B 1 108 ? 80.865  102.982 100.156 1.00 110.29 ? 108 ASP B O   1 
ATOM   5150  C CB  . ASP B 1 108 ? 77.795  102.850 99.279  1.00 110.68 ? 108 ASP B CB  1 
ATOM   5151  C CG  . ASP B 1 108 ? 76.519  103.367 98.605  1.00 110.92 ? 108 ASP B CG  1 
ATOM   5152  O OD1 . ASP B 1 108 ? 76.044  104.464 98.965  1.00 110.70 ? 108 ASP B OD1 1 
ATOM   5153  O OD2 . ASP B 1 108 ? 75.955  102.629 97.772  1.00 111.02 ? 108 ASP B OD2 1 
ATOM   5154  N N   . SER B 1 109 ? 79.563  102.950 101.986 1.00 107.64 ? 109 SER B N   1 
ATOM   5155  C CA  . SER B 1 109 ? 80.579  102.426 102.919 1.00 108.90 ? 109 SER B CA  1 
ATOM   5156  C C   . SER B 1 109 ? 81.364  101.226 102.370 1.00 108.21 ? 109 SER B C   1 
ATOM   5157  O O   . SER B 1 109 ? 82.585  101.163 102.529 1.00 107.47 ? 109 SER B O   1 
ATOM   5158  C CB  . SER B 1 109 ? 79.900  102.063 104.246 1.00 107.50 ? 109 SER B CB  1 
ATOM   5159  O OG  . SER B 1 109 ? 80.843  101.596 105.188 1.00 106.76 ? 109 SER B OG  1 
ATOM   5160  N N   . ALA B 1 110 ? 80.702  100.329 101.635 1.00 110.05 ? 110 ALA B N   1 
ATOM   5161  C CA  . ALA B 1 110 ? 81.315  99.160  101.005 1.00 109.78 ? 110 ALA B CA  1 
ATOM   5162  C C   . ALA B 1 110 ? 82.509  99.482  100.082 1.00 110.38 ? 110 ALA B C   1 
ATOM   5163  O O   . ALA B 1 110 ? 83.438  98.682  100.000 1.00 110.68 ? 110 ALA B O   1 
ATOM   5164  C CB  . ALA B 1 110 ? 80.219  98.429  100.226 1.00 108.63 ? 110 ALA B CB  1 
ATOM   5165  N N   . TYR B 1 111 ? 82.520  100.651 99.427  1.00 107.69 ? 111 TYR B N   1 
ATOM   5166  C CA  . TYR B 1 111 ? 83.597  101.104 98.535  1.00 107.38 ? 111 TYR B CA  1 
ATOM   5167  C C   . TYR B 1 111 ? 84.615  102.038 99.225  1.00 106.70 ? 111 TYR B C   1 
ATOM   5168  O O   . TYR B 1 111 ? 85.368  102.744 98.555  1.00 106.91 ? 111 TYR B O   1 
ATOM   5169  C CB  . TYR B 1 111 ? 82.993  101.689 97.248  1.00 107.86 ? 111 TYR B CB  1 
ATOM   5170  C CG  . TYR B 1 111 ? 82.309  100.659 96.366  1.00 108.31 ? 111 TYR B CG  1 
ATOM   5171  C CD1 . TYR B 1 111 ? 83.087  99.824  95.539  1.00 107.74 ? 111 TYR B CD1 1 
ATOM   5172  C CD2 . TYR B 1 111 ? 80.910  100.528 96.369  1.00 109.10 ? 111 TYR B CD2 1 
ATOM   5173  C CE1 . TYR B 1 111 ? 82.473  98.862  94.716  1.00 108.56 ? 111 TYR B CE1 1 
ATOM   5174  C CE2 . TYR B 1 111 ? 80.293  99.550  95.564  1.00 108.60 ? 111 TYR B CE2 1 
ATOM   5175  C CZ  . TYR B 1 111 ? 81.072  98.714  94.737  1.00 109.01 ? 111 TYR B CZ  1 
ATOM   5176  O OH  . TYR B 1 111 ? 80.468  97.762  93.979  1.00 109.27 ? 111 TYR B OH  1 
ATOM   5177  N N   . THR B 1 112 ? 84.689  102.030 100.561 1.00 98.27  ? 112 THR B N   1 
ATOM   5178  C CA  . THR B 1 112 ? 85.598  102.875 101.360 1.00 98.01  ? 112 THR B CA  1 
ATOM   5179  C C   . THR B 1 112 ? 86.599  102.063 102.187 1.00 97.99  ? 112 THR B C   1 
ATOM   5180  O O   . THR B 1 112 ? 86.328  100.917 102.530 1.00 99.37  ? 112 THR B O   1 
ATOM   5181  C CB  . THR B 1 112 ? 84.833  103.834 102.282 1.00 97.28  ? 112 THR B CB  1 
ATOM   5182  O OG1 . THR B 1 112 ? 84.258  103.162 103.377 1.00 97.07  ? 112 THR B OG1 1 
ATOM   5183  C CG2 . THR B 1 112 ? 83.733  104.618 101.577 1.00 96.67  ? 112 THR B CG2 1 
ATOM   5184  N N   . GLU B 1 113 ? 87.739  102.655 102.571 1.00 91.89  ? 113 GLU B N   1 
ATOM   5185  C CA  . GLU B 1 113 ? 88.744  101.989 103.430 1.00 91.95  ? 113 GLU B CA  1 
ATOM   5186  C C   . GLU B 1 113 ? 88.223  101.607 104.835 1.00 91.71  ? 113 GLU B C   1 
ATOM   5187  O O   . GLU B 1 113 ? 88.884  100.861 105.556 1.00 92.32  ? 113 GLU B O   1 
ATOM   5188  C CB  . GLU B 1 113 ? 90.033  102.830 103.550 1.00 90.83  ? 113 GLU B CB  1 
ATOM   5189  C CG  . GLU B 1 113 ? 90.742  103.065 102.206 1.00 92.23  ? 113 GLU B CG  1 
ATOM   5190  C CD  . GLU B 1 113 ? 92.267  102.871 102.265 1.00 93.31  ? 113 GLU B CD  1 
ATOM   5191  O OE1 . GLU B 1 113 ? 92.971  103.672 102.918 1.00 92.52  ? 113 GLU B OE1 1 
ATOM   5192  O OE2 . GLU B 1 113 ? 92.780  101.942 101.599 1.00 93.27  ? 113 GLU B OE2 1 
ATOM   5193  N N   . GLY B 1 114 ? 87.034  102.076 105.228 1.00 85.24  ? 114 GLY B N   1 
ATOM   5194  C CA  . GLY B 1 114 ? 86.276  101.591 106.390 1.00 86.53  ? 114 GLY B CA  1 
ATOM   5195  C C   . GLY B 1 114 ? 86.747  102.098 107.754 1.00 84.79  ? 114 GLY B C   1 
ATOM   5196  O O   . GLY B 1 114 ? 85.928  102.520 108.570 1.00 82.57  ? 114 GLY B O   1 
ATOM   5197  N N   . SER B 1 115 ? 88.057  102.125 107.998 1.00 82.00  ? 115 SER B N   1 
ATOM   5198  C CA  . SER B 1 115 ? 88.654  102.715 109.204 1.00 82.72  ? 115 SER B CA  1 
ATOM   5199  C C   . SER B 1 115 ? 88.497  104.240 109.257 1.00 84.08  ? 115 SER B C   1 
ATOM   5200  O O   . SER B 1 115 ? 88.360  104.809 110.339 1.00 80.97  ? 115 SER B O   1 
ATOM   5201  C CB  . SER B 1 115 ? 90.135  102.326 109.280 1.00 80.42  ? 115 SER B CB  1 
ATOM   5202  O OG  . SER B 1 115 ? 90.835  102.728 108.117 1.00 80.27  ? 115 SER B OG  1 
ATOM   5203  N N   . THR B 1 116 ? 88.468  104.897 108.092 1.00 79.80  ? 116 THR B N   1 
ATOM   5204  C CA  . THR B 1 116 ? 88.375  106.362 107.942 1.00 77.34  ? 116 THR B CA  1 
ATOM   5205  C C   . THR B 1 116 ? 87.225  106.837 107.050 1.00 75.68  ? 116 THR B C   1 
ATOM   5206  O O   . THR B 1 116 ? 86.907  108.020 107.046 1.00 77.45  ? 116 THR B O   1 
ATOM   5207  C CB  . THR B 1 116 ? 89.687  106.921 107.372 1.00 76.51  ? 116 THR B CB  1 
ATOM   5208  O OG1 . THR B 1 116 ? 89.901  106.355 106.097 1.00 76.06  ? 116 THR B OG1 1 
ATOM   5209  C CG2 . THR B 1 116 ? 90.922  106.589 108.205 1.00 76.21  ? 116 THR B CG2 1 
ATOM   5210  N N   . GLY B 1 117 ? 86.575  105.967 106.267 1.00 77.21  ? 117 GLY B N   1 
ATOM   5211  C CA  . GLY B 1 117 ? 85.560  106.431 105.297 1.00 77.79  ? 117 GLY B CA  1 
ATOM   5212  C C   . GLY B 1 117 ? 86.232  107.069 104.089 1.00 77.65  ? 117 GLY B C   1 
ATOM   5213  O O   . GLY B 1 117 ? 85.620  107.976 103.491 1.00 78.08  ? 117 GLY B O   1 
ATOM   5214  N N   . LYS B 1 118 ? 87.443  106.618 103.742 1.00 78.99  ? 118 LYS B N   1 
ATOM   5215  C CA  . LYS B 1 118 ? 88.218  107.184 102.598 1.00 78.36  ? 118 LYS B CA  1 
ATOM   5216  C C   . LYS B 1 118 ? 87.804  106.464 101.320 1.00 78.60  ? 118 LYS B C   1 
ATOM   5217  O O   . LYS B 1 118 ? 87.628  105.235 101.403 1.00 82.27  ? 118 LYS B O   1 
ATOM   5218  C CB  . LYS B 1 118 ? 89.691  107.019 102.928 1.00 78.39  ? 118 LYS B CB  1 
ATOM   5219  C CG  . LYS B 1 118 ? 90.720  107.147 101.801 1.00 79.70  ? 118 LYS B CG  1 
ATOM   5220  C CD  . LYS B 1 118 ? 92.112  106.723 102.212 1.00 80.69  ? 118 LYS B CD  1 
ATOM   5221  C CE  . LYS B 1 118 ? 93.076  106.649 101.047 1.00 80.63  ? 118 LYS B CE  1 
ATOM   5222  N NZ  . LYS B 1 118 ? 94.410  106.162 101.473 1.00 81.28  ? 118 LYS B NZ  1 
ATOM   5223  N N   . THR B 1 119 ? 87.652  107.146 100.185 1.00 80.46  ? 119 THR B N   1 
ATOM   5224  C CA  . THR B 1 119 ? 87.044  106.601 98.951  1.00 80.65  ? 119 THR B CA  1 
ATOM   5225  C C   . THR B 1 119 ? 88.057  106.232 97.860  1.00 79.21  ? 119 THR B C   1 
ATOM   5226  O O   . THR B 1 119 ? 89.237  106.583 97.929  1.00 77.95  ? 119 THR B O   1 
ATOM   5227  C CB  . THR B 1 119 ? 86.015  107.595 98.374  1.00 82.00  ? 119 THR B CB  1 
ATOM   5228  O OG1 . THR B 1 119 ? 86.662  108.749 97.884  1.00 80.18  ? 119 THR B OG1 1 
ATOM   5229  C CG2 . THR B 1 119 ? 84.970  108.039 99.390  1.00 80.48  ? 119 THR B CG2 1 
ATOM   5230  N N   . CYS B 1 120 ? 87.590  105.572 96.799  1.00 85.58  ? 120 CYS B N   1 
ATOM   5231  C CA  . CYS B 1 120 ? 88.375  105.262 95.604  1.00 87.13  ? 120 CYS B CA  1 
ATOM   5232  C C   . CYS B 1 120 ? 88.937  106.517 94.922  1.00 84.99  ? 120 CYS B C   1 
ATOM   5233  O O   . CYS B 1 120 ? 90.076  106.490 94.475  1.00 83.99  ? 120 CYS B O   1 
ATOM   5234  C CB  . CYS B 1 120 ? 87.489  104.455 94.643  1.00 86.44  ? 120 CYS B CB  1 
ATOM   5235  S SG  . CYS B 1 120 ? 85.961  105.362 94.302  1.00 87.55  ? 120 CYS B SG  1 
ATOM   5236  N N   . LEU B 1 121 ? 88.199  107.635 94.900  1.00 80.77  ? 121 LEU B N   1 
ATOM   5237  C CA  . LEU B 1 121 ? 88.691  108.911 94.363  1.00 80.01  ? 121 LEU B CA  1 
ATOM   5238  C C   . LEU B 1 121 ? 89.854  109.466 95.190  1.00 78.17  ? 121 LEU B C   1 
ATOM   5239  O O   . LEU B 1 121 ? 90.861  109.872 94.624  1.00 77.39  ? 121 LEU B O   1 
ATOM   5240  C CB  . LEU B 1 121 ? 87.530  109.913 94.268  1.00 78.46  ? 121 LEU B CB  1 
ATOM   5241  C CG  . LEU B 1 121 ? 87.947  111.317 93.802  1.00 78.65  ? 121 LEU B CG  1 
ATOM   5242  C CD1 . LEU B 1 121 ? 88.475  111.312 92.375  1.00 78.23  ? 121 LEU B CD1 1 
ATOM   5243  C CD2 . LEU B 1 121 ? 86.746  112.247 93.855  1.00 78.05  ? 121 LEU B CD2 1 
ATOM   5244  N N   . MET B 1 122 ? 89.785  109.425 96.521  1.00 73.09  ? 122 MET B N   1 
ATOM   5245  C CA  . MET B 1 122 ? 90.932  109.798 97.355  1.00 73.38  ? 122 MET B CA  1 
ATOM   5246  C C   . MET B 1 122 ? 92.136  108.897 97.072  1.00 75.13  ? 122 MET B C   1 
ATOM   5247  O O   . MET B 1 122 ? 93.253  109.387 96.912  1.00 72.75  ? 122 MET B O   1 
ATOM   5248  C CB  . MET B 1 122 ? 90.569  109.717 98.836  1.00 72.11  ? 122 MET B CB  1 
ATOM   5249  C CG  . MET B 1 122 ? 89.460  110.687 99.220  1.00 70.76  ? 122 MET B CG  1 
ATOM   5250  S SD  . MET B 1 122 ? 89.022  110.558 100.961 1.00 76.71  ? 122 MET B SD  1 
ATOM   5251  C CE  . MET B 1 122 ? 87.368  111.262 100.907 1.00 71.77  ? 122 MET B CE  1 
ATOM   5252  N N   . LYS B 1 123 ? 91.913  107.584 96.937  1.00 82.09  ? 123 LYS B N   1 
ATOM   5253  C CA  . LYS B 1 123 ? 92.977  106.630 96.592  1.00 80.91  ? 123 LYS B CA  1 
ATOM   5254  C C   . LYS B 1 123 ? 93.501  106.784 95.151  1.00 79.18  ? 123 LYS B C   1 
ATOM   5255  O O   . LYS B 1 123 ? 94.636  106.404 94.896  1.00 79.42  ? 123 LYS B O   1 
ATOM   5256  C CB  . LYS B 1 123 ? 92.506  105.206 96.940  1.00 81.91  ? 123 LYS B CB  1 
ATOM   5257  C CG  . LYS B 1 123 ? 93.685  104.276 97.249  1.00 82.47  ? 123 LYS B CG  1 
ATOM   5258  C CD  . LYS B 1 123 ? 93.258  103.016 98.007  1.00 82.52  ? 123 LYS B CD  1 
ATOM   5259  C CE  . LYS B 1 123 ? 94.499  102.224 98.433  1.00 82.96  ? 123 LYS B CE  1 
ATOM   5260  N NZ  . LYS B 1 123 ? 94.190  101.128 99.382  1.00 83.82  ? 123 LYS B NZ  1 
ATOM   5261  N N   . ALA B 1 124 ? 92.725  107.375 94.243  1.00 79.04  ? 124 ALA B N   1 
ATOM   5262  C CA  . ALA B 1 124 ? 93.150  107.780 92.899  1.00 79.68  ? 124 ALA B CA  1 
ATOM   5263  C C   . ALA B 1 124 ? 93.996  109.071 92.906  1.00 79.53  ? 124 ALA B C   1 
ATOM   5264  O O   . ALA B 1 124 ? 94.933  109.201 92.122  1.00 80.54  ? 124 ALA B O   1 
ATOM   5265  C CB  . ALA B 1 124 ? 91.903  107.987 92.030  1.00 78.54  ? 124 ALA B CB  1 
ATOM   5266  N N   . VAL B 1 125 ? 93.656  110.041 93.764  1.00 74.40  ? 125 VAL B N   1 
ATOM   5267  C CA  . VAL B 1 125 ? 94.396  111.305 93.917  1.00 72.94  ? 125 VAL B CA  1 
ATOM   5268  C C   . VAL B 1 125 ? 95.724  111.093 94.662  1.00 73.58  ? 125 VAL B C   1 
ATOM   5269  O O   . VAL B 1 125 ? 96.701  111.790 94.404  1.00 73.37  ? 125 VAL B O   1 
ATOM   5270  C CB  . VAL B 1 125 ? 93.505  112.363 94.598  1.00 70.50  ? 125 VAL B CB  1 
ATOM   5271  C CG1 . VAL B 1 125 ? 94.245  113.665 94.875  1.00 69.26  ? 125 VAL B CG1 1 
ATOM   5272  C CG2 . VAL B 1 125 ? 92.314  112.740 93.711  1.00 71.38  ? 125 VAL B CG2 1 
ATOM   5273  N N   . LEU B 1 126 ? 95.816  110.098 95.545  1.00 71.90  ? 126 LEU B N   1 
ATOM   5274  C CA  . LEU B 1 126 ? 97.105  109.576 96.017  1.00 71.31  ? 126 LEU B CA  1 
ATOM   5275  C C   . LEU B 1 126 ? 97.861  108.851 94.883  1.00 74.39  ? 126 LEU B C   1 
ATOM   5276  O O   . LEU B 1 126 ? 97.261  108.240 94.008  1.00 77.05  ? 126 LEU B O   1 
ATOM   5277  C CB  . LEU B 1 126 ? 96.868  108.662 97.228  1.00 71.57  ? 126 LEU B CB  1 
ATOM   5278  C CG  . LEU B 1 126 ? 96.293  109.407 98.446  1.00 69.04  ? 126 LEU B CG  1 
ATOM   5279  C CD1 . LEU B 1 126 ? 95.783  108.424 99.487  1.00 67.47  ? 126 LEU B CD1 1 
ATOM   5280  C CD2 . LEU B 1 126 ? 97.343  110.301 99.092  1.00 68.13  ? 126 LEU B CD2 1 
ATOM   5281  N N   . ASN B 1 127 ? 99.199  108.915 94.897  1.00 81.78  ? 127 ASN B N   1 
ATOM   5282  C CA  . ASN B 1 127 ? 100.044 108.270 93.849  1.00 84.68  ? 127 ASN B CA  1 
ATOM   5283  C C   . ASN B 1 127 ? 99.639  108.785 92.460  1.00 83.67  ? 127 ASN B C   1 
ATOM   5284  O O   . ASN B 1 127 ? 98.961  108.040 91.725  1.00 81.53  ? 127 ASN B O   1 
ATOM   5285  C CB  . ASN B 1 127 ? 100.086 106.737 93.967  1.00 84.29  ? 127 ASN B CB  1 
ATOM   5286  C CG  . ASN B 1 127 ? 98.737  106.051 93.900  1.00 84.06  ? 127 ASN B CG  1 
ATOM   5287  O OD1 . ASN B 1 127 ? 98.275  105.679 92.824  1.00 84.79  ? 127 ASN B OD1 1 
ATOM   5288  N ND2 . ASN B 1 127 ? 98.105  105.866 95.047  1.00 82.51  ? 127 ASN B ND2 1 
ATOM   5289  N N   . LEU B 1 128 ? 100.045 110.013 92.119  1.00 88.67  ? 128 LEU B N   1 
ATOM   5290  C CA  . LEU B 1 128 ? 99.766  110.565 90.764  1.00 86.50  ? 128 LEU B CA  1 
ATOM   5291  C C   . LEU B 1 128 ? 101.029 110.417 89.911  1.00 88.71  ? 128 LEU B C   1 
ATOM   5292  O O   . LEU B 1 128 ? 102.124 110.714 90.428  1.00 88.00  ? 128 LEU B O   1 
ATOM   5293  C CB  . LEU B 1 128 ? 99.360  112.036 90.890  1.00 88.40  ? 128 LEU B CB  1 
ATOM   5294  C CG  . LEU B 1 128 ? 98.067  112.297 91.660  1.00 87.99  ? 128 LEU B CG  1 
ATOM   5295  C CD1 . LEU B 1 128 ? 97.749  113.784 91.696  1.00 86.78  ? 128 LEU B CD1 1 
ATOM   5296  C CD2 . LEU B 1 128 ? 96.910  111.522 91.049  1.00 86.79  ? 128 LEU B CD2 1 
ATOM   5297  N N   . GLN B 1 129 ? 100.882 109.978 88.658  1.00 99.13  ? 129 GLN B N   1 
ATOM   5298  C CA  . GLN B 1 129 ? 102.044 109.752 87.792  1.00 98.53  ? 129 GLN B CA  1 
ATOM   5299  C C   . GLN B 1 129 ? 102.315 111.007 86.951  1.00 98.99  ? 129 GLN B C   1 
ATOM   5300  O O   . GLN B 1 129 ? 101.420 111.504 86.269  1.00 99.43  ? 129 GLN B O   1 
ATOM   5301  C CB  . GLN B 1 129 ? 101.796 108.524 86.899  1.00 98.10  ? 129 GLN B CB  1 
ATOM   5302  C CG  . GLN B 1 129 ? 101.527 107.238 87.700  1.00 97.97  ? 129 GLN B CG  1 
ATOM   5303  C CD  . GLN B 1 129 ? 101.395 105.989 86.831  1.00 100.35 ? 129 GLN B CD  1 
ATOM   5304  O OE1 . GLN B 1 129 ? 101.462 106.012 85.610  1.00 99.99  ? 129 GLN B OE1 1 
ATOM   5305  N NE2 . GLN B 1 129 ? 101.205 104.837 87.430  1.00 99.45  ? 129 GLN B NE2 1 
ATOM   5306  N N   . ASP B 1 130 ? 103.515 111.590 87.024  1.00 98.50  ? 130 ASP B N   1 
ATOM   5307  C CA  . ASP B 1 130 ? 103.839 112.865 86.359  1.00 99.35  ? 130 ASP B CA  1 
ATOM   5308  C C   . ASP B 1 130 ? 102.851 114.019 86.651  1.00 98.79  ? 130 ASP B C   1 
ATOM   5309  O O   . ASP B 1 130 ? 102.629 114.902 85.819  1.00 98.45  ? 130 ASP B O   1 
ATOM   5310  C CB  . ASP B 1 130 ? 104.033 112.626 84.862  1.00 98.90  ? 130 ASP B CB  1 
ATOM   5311  N N   . GLY B 1 131 ? 102.224 114.004 87.833  1.00 92.19  ? 131 GLY B N   1 
ATOM   5312  C CA  . GLY B 1 131 ? 101.240 114.991 88.280  1.00 92.49  ? 131 GLY B CA  1 
ATOM   5313  C C   . GLY B 1 131 ? 99.776  114.719 87.903  1.00 92.69  ? 131 GLY B C   1 
ATOM   5314  O O   . GLY B 1 131 ? 98.926  115.544 88.230  1.00 92.12  ? 131 GLY B O   1 
ATOM   5315  N N   . VAL B 1 132 ? 99.445  113.591 87.261  1.00 93.37  ? 132 VAL B N   1 
ATOM   5316  C CA  . VAL B 1 132 ? 98.070  113.252 86.831  1.00 94.39  ? 132 VAL B CA  1 
ATOM   5317  C C   . VAL B 1 132 ? 97.732  111.764 87.037  1.00 93.30  ? 132 VAL B C   1 
ATOM   5318  O O   . VAL B 1 132 ? 98.611  110.928 87.216  1.00 92.56  ? 132 VAL B O   1 
ATOM   5319  C CB  . VAL B 1 132 ? 97.859  113.738 85.381  1.00 95.87  ? 132 VAL B CB  1 
ATOM   5320  C CG1 . VAL B 1 132 ? 98.632  112.914 84.352  1.00 94.85  ? 132 VAL B CG1 1 
ATOM   5321  C CG2 . VAL B 1 132 ? 96.384  113.791 84.971  1.00 93.64  ? 132 VAL B CG2 1 
ATOM   5322  N N   . ASN B 1 133 ? 96.445  111.416 87.035  1.00 94.06  ? 133 ASN B N   1 
ATOM   5323  C CA  . ASN B 1 133 ? 95.979  110.029 87.038  1.00 94.69  ? 133 ASN B CA  1 
ATOM   5324  C C   . ASN B 1 133 ? 94.786  109.875 86.080  1.00 94.20  ? 133 ASN B C   1 
ATOM   5325  O O   . ASN B 1 133 ? 93.713  110.442 86.308  1.00 94.08  ? 133 ASN B O   1 
ATOM   5326  C CB  . ASN B 1 133 ? 95.663  109.611 88.485  1.00 94.48  ? 133 ASN B CB  1 
ATOM   5327  C CG  . ASN B 1 133 ? 95.169  108.183 88.622  1.00 93.51  ? 133 ASN B CG  1 
ATOM   5328  O OD1 . ASN B 1 133 ? 94.775  107.531 87.669  1.00 95.02  ? 133 ASN B OD1 1 
ATOM   5329  N ND2 . ASN B 1 133 ? 95.180  107.652 89.812  1.00 92.72  ? 133 ASN B ND2 1 
ATOM   5330  N N   . ALA B 1 134 ? 94.966  109.083 85.023  1.00 96.21  ? 134 ALA B N   1 
ATOM   5331  C CA  . ALA B 1 134 ? 93.967  108.864 83.974  1.00 96.93  ? 134 ALA B CA  1 
ATOM   5332  C C   . ALA B 1 134 ? 92.651  108.232 84.466  1.00 97.70  ? 134 ALA B C   1 
ATOM   5333  O O   . ALA B 1 134 ? 91.637  108.326 83.780  1.00 98.40  ? 134 ALA B O   1 
ATOM   5334  C CB  . ALA B 1 134 ? 94.613  107.995 82.890  1.00 97.40  ? 134 ALA B CB  1 
ATOM   5335  N N   . CYS B 1 135 ? 92.638  107.614 85.649  1.00 97.37  ? 135 CYS B N   1 
ATOM   5336  C CA  . CYS B 1 135 ? 91.454  106.999 86.248  1.00 97.56  ? 135 CYS B CA  1 
ATOM   5337  C C   . CYS B 1 135 ? 90.470  108.007 86.884  1.00 99.00  ? 135 CYS B C   1 
ATOM   5338  O O   . CYS B 1 135 ? 89.286  107.706 87.013  1.00 98.08  ? 135 CYS B O   1 
ATOM   5339  C CB  . CYS B 1 135 ? 91.963  105.959 87.252  1.00 98.69  ? 135 CYS B CB  1 
ATOM   5340  S SG  . CYS B 1 135 ? 90.618  104.903 87.832  1.00 103.17 ? 135 CYS B SG  1 
ATOM   5341  N N   . ILE B 1 136 ? 90.908  109.226 87.242  1.00 96.04  ? 136 ILE B N   1 
ATOM   5342  C CA  . ILE B 1 136 ? 90.064  110.182 87.989  1.00 94.57  ? 136 ILE B CA  1 
ATOM   5343  C C   . ILE B 1 136 ? 88.818  110.604 87.190  1.00 94.76  ? 136 ILE B C   1 
ATOM   5344  O O   . ILE B 1 136 ? 87.702  110.523 87.707  1.00 94.69  ? 136 ILE B O   1 
ATOM   5345  C CB  . ILE B 1 136 ? 90.897  111.388 88.486  1.00 94.45  ? 136 ILE B CB  1 
ATOM   5346  C CG1 . ILE B 1 136 ? 91.921  110.920 89.542  1.00 93.41  ? 136 ILE B CG1 1 
ATOM   5347  C CG2 . ILE B 1 136 ? 89.986  112.462 89.100  1.00 94.90  ? 136 ILE B CG2 1 
ATOM   5348  C CD1 . ILE B 1 136 ? 92.939  111.989 89.954  1.00 92.27  ? 136 ILE B CD1 1 
ATOM   5349  N N   . MET B 1 137 ? 88.966  111.011 85.922  1.00 98.27  ? 137 MET B N   1 
ATOM   5350  C CA  . MET B 1 137 ? 87.809  111.346 85.078  1.00 98.89  ? 137 MET B CA  1 
ATOM   5351  C C   . MET B 1 137 ? 86.828  110.163 84.915  1.00 99.81  ? 137 MET B C   1 
ATOM   5352  O O   . MET B 1 137 ? 85.654  110.353 85.218  1.00 98.91  ? 137 MET B O   1 
ATOM   5353  C CB  . MET B 1 137 ? 88.238  111.926 83.720  1.00 98.90  ? 137 MET B CB  1 
ATOM   5354  C CG  . MET B 1 137 ? 88.745  113.360 83.804  1.00 99.18  ? 137 MET B CG  1 
ATOM   5355  S SD  . MET B 1 137 ? 89.155  114.050 82.180  1.00 103.27 ? 137 MET B SD  1 
ATOM   5356  C CE  . MET B 1 137 ? 89.777  115.679 82.650  1.00 98.88  ? 137 MET B CE  1 
ATOM   5357  N N   . PRO B 1 138 ? 87.255  108.941 84.531  1.00 100.30 ? 138 PRO B N   1 
ATOM   5358  C CA  . PRO B 1 138 ? 86.417  107.742 84.555  1.00 99.91  ? 138 PRO B CA  1 
ATOM   5359  C C   . PRO B 1 138 ? 85.654  107.494 85.861  1.00 100.71 ? 138 PRO B C   1 
ATOM   5360  O O   . PRO B 1 138 ? 84.460  107.205 85.804  1.00 100.65 ? 138 PRO B O   1 
ATOM   5361  C CB  . PRO B 1 138 ? 87.366  106.582 84.259  1.00 101.14 ? 138 PRO B CB  1 
ATOM   5362  C CG  . PRO B 1 138 ? 88.399  107.215 83.342  1.00 100.45 ? 138 PRO B CG  1 
ATOM   5363  C CD  . PRO B 1 138 ? 88.512  108.639 83.868  1.00 99.80  ? 138 PRO B CD  1 
ATOM   5364  N N   . LEU B 1 139 ? 86.273  107.647 87.039  1.00 98.66  ? 139 LEU B N   1 
ATOM   5365  C CA  . LEU B 1 139 ? 85.566  107.512 88.326  1.00 98.69  ? 139 LEU B CA  1 
ATOM   5366  C C   . LEU B 1 139 ? 84.444  108.546 88.477  1.00 99.71  ? 139 LEU B C   1 
ATOM   5367  O O   . LEU B 1 139 ? 83.329  108.201 88.860  1.00 99.21  ? 139 LEU B O   1 
ATOM   5368  C CB  . LEU B 1 139 ? 86.543  107.684 89.501  1.00 99.01  ? 139 LEU B CB  1 
ATOM   5369  C CG  . LEU B 1 139 ? 87.560  106.551 89.677  1.00 99.85  ? 139 LEU B CG  1 
ATOM   5370  C CD1 . LEU B 1 139 ? 88.642  107.016 90.648  1.00 99.03  ? 139 LEU B CD1 1 
ATOM   5371  C CD2 . LEU B 1 139 ? 86.895  105.295 90.248  1.00 100.37 ? 139 LEU B CD2 1 
ATOM   5372  N N   . LEU B 1 140 ? 84.723  109.814 88.162  1.00 98.12  ? 140 LEU B N   1 
ATOM   5373  C CA  . LEU B 1 140 ? 83.742  110.899 88.233  1.00 98.40  ? 140 LEU B CA  1 
ATOM   5374  C C   . LEU B 1 140 ? 82.626  110.730 87.187  1.00 97.90  ? 140 LEU B C   1 
ATOM   5375  O O   . LEU B 1 140 ? 81.462  110.994 87.475  1.00 97.83  ? 140 LEU B O   1 
ATOM   5376  C CB  . LEU B 1 140 ? 84.476  112.243 88.073  1.00 97.32  ? 140 LEU B CB  1 
ATOM   5377  C CG  . LEU B 1 140 ? 85.443  112.574 89.231  1.00 96.23  ? 140 LEU B CG  1 
ATOM   5378  C CD1 . LEU B 1 140 ? 86.356  113.732 88.846  1.00 95.62  ? 140 LEU B CD1 1 
ATOM   5379  C CD2 . LEU B 1 140 ? 84.684  112.954 90.495  1.00 95.66  ? 140 LEU B CD2 1 
ATOM   5380  N N   . GLN B 1 141 ? 82.949  110.243 85.986  1.00 101.73 ? 141 GLN B N   1 
ATOM   5381  C CA  . GLN B 1 141 ? 81.976  109.875 84.960  1.00 102.82 ? 141 GLN B CA  1 
ATOM   5382  C C   . GLN B 1 141 ? 81.067  108.741 85.449  1.00 102.24 ? 141 GLN B C   1 
ATOM   5383  O O   . GLN B 1 141 ? 79.851  108.889 85.420  1.00 102.65 ? 141 GLN B O   1 
ATOM   5384  C CB  . GLN B 1 141 ? 82.703  109.482 83.666  1.00 102.16 ? 141 GLN B CB  1 
ATOM   5385  C CG  . GLN B 1 141 ? 83.336  110.695 82.964  1.00 102.59 ? 141 GLN B CG  1 
ATOM   5386  C CD  . GLN B 1 141 ? 84.366  110.325 81.897  1.00 102.54 ? 141 GLN B CD  1 
ATOM   5387  O OE1 . GLN B 1 141 ? 84.603  109.173 81.561  1.00 101.91 ? 141 GLN B OE1 1 
ATOM   5388  N NE2 . GLN B 1 141 ? 85.019  111.301 81.306  1.00 101.78 ? 141 GLN B NE2 1 
ATOM   5389  N N   . ILE B 1 142 ? 81.629  107.646 85.970  1.00 103.52 ? 142 ILE B N   1 
ATOM   5390  C CA  . ILE B 1 142 ? 80.857  106.523 86.525  1.00 104.66 ? 142 ILE B CA  1 
ATOM   5391  C C   . ILE B 1 142 ? 79.979  106.981 87.698  1.00 104.15 ? 142 ILE B C   1 
ATOM   5392  O O   . ILE B 1 142 ? 78.844  106.530 87.826  1.00 103.82 ? 142 ILE B O   1 
ATOM   5393  C CB  . ILE B 1 142 ? 81.811  105.368 86.914  1.00 104.24 ? 142 ILE B CB  1 
ATOM   5394  C CG1 . ILE B 1 142 ? 82.367  104.717 85.628  1.00 104.41 ? 142 ILE B CG1 1 
ATOM   5395  C CG2 . ILE B 1 142 ? 81.133  104.305 87.792  1.00 103.86 ? 142 ILE B CG2 1 
ATOM   5396  C CD1 . ILE B 1 142 ? 83.534  103.763 85.863  1.00 104.64 ? 142 ILE B CD1 1 
ATOM   5397  N N   . ASP B 1 143 ? 80.449  107.884 88.559  1.00 103.46 ? 143 ASP B N   1 
ATOM   5398  C CA  . ASP B 1 143 ? 79.643  108.402 89.669  1.00 102.99 ? 143 ASP B CA  1 
ATOM   5399  C C   . ASP B 1 143 ? 78.440  109.240 89.188  1.00 103.96 ? 143 ASP B C   1 
ATOM   5400  O O   . ASP B 1 143 ? 77.312  109.031 89.636  1.00 103.29 ? 143 ASP B O   1 
ATOM   5401  C CB  . ASP B 1 143 ? 80.529  109.226 90.608  1.00 102.31 ? 143 ASP B CB  1 
ATOM   5402  C CG  . ASP B 1 143 ? 79.777  109.564 91.897  1.00 103.79 ? 143 ASP B CG  1 
ATOM   5403  O OD1 . ASP B 1 143 ? 79.263  108.626 92.544  1.00 103.82 ? 143 ASP B OD1 1 
ATOM   5404  O OD2 . ASP B 1 143 ? 79.728  110.756 92.265  1.00 103.77 ? 143 ASP B OD2 1 
ATOM   5405  N N   . LYS B 1 144 ? 78.659  110.146 88.224  1.00 105.63 ? 144 LYS B N   1 
ATOM   5406  C CA  . LYS B 1 144 ? 77.588  110.940 87.586  1.00 104.84 ? 144 LYS B CA  1 
ATOM   5407  C C   . LYS B 1 144 ? 76.606  110.056 86.811  1.00 104.99 ? 144 LYS B C   1 
ATOM   5408  O O   . LYS B 1 144 ? 75.395  110.211 86.949  1.00 104.31 ? 144 LYS B O   1 
ATOM   5409  C CB  . LYS B 1 144 ? 78.208  112.015 86.674  1.00 104.36 ? 144 LYS B CB  1 
ATOM   5410  C CG  . LYS B 1 144 ? 78.888  113.131 87.482  1.00 105.16 ? 144 LYS B CG  1 
ATOM   5411  C CD  . LYS B 1 144 ? 79.545  114.221 86.621  1.00 104.04 ? 144 LYS B CD  1 
ATOM   5412  C CE  . LYS B 1 144 ? 80.675  113.689 85.731  1.00 104.11 ? 144 LYS B CE  1 
ATOM   5413  N NZ  . LYS B 1 144 ? 81.391  114.789 85.032  1.00 103.81 ? 144 LYS B NZ  1 
ATOM   5414  N N   . ASP B 1 145 ? 77.108  109.075 86.060  1.00 109.07 ? 145 ASP B N   1 
ATOM   5415  C CA  . ASP B 1 145 ? 76.302  108.077 85.345  1.00 108.90 ? 145 ASP B CA  1 
ATOM   5416  C C   . ASP B 1 145 ? 75.514  107.141 86.281  1.00 108.59 ? 145 ASP B C   1 
ATOM   5417  O O   . ASP B 1 145 ? 74.467  106.622 85.894  1.00 109.56 ? 145 ASP B O   1 
ATOM   5418  C CB  . ASP B 1 145 ? 77.197  107.249 84.407  1.00 108.84 ? 145 ASP B CB  1 
ATOM   5419  C CG  . ASP B 1 145 ? 77.817  108.037 83.240  1.00 108.99 ? 145 ASP B CG  1 
ATOM   5420  O OD1 . ASP B 1 145 ? 77.344  109.156 82.930  1.00 109.19 ? 145 ASP B OD1 1 
ATOM   5421  O OD2 . ASP B 1 145 ? 78.724  107.495 82.569  1.00 107.95 ? 145 ASP B OD2 1 
ATOM   5422  N N   . SER B 1 146 ? 75.965  106.943 87.520  1.00 109.43 ? 146 SER B N   1 
ATOM   5423  C CA  . SER B 1 146 ? 75.232  106.180 88.543  1.00 110.01 ? 146 SER B CA  1 
ATOM   5424  C C   . SER B 1 146 ? 74.066  106.957 89.173  1.00 109.75 ? 146 SER B C   1 
ATOM   5425  O O   . SER B 1 146 ? 73.222  106.349 89.827  1.00 109.08 ? 146 SER B O   1 
ATOM   5426  C CB  . SER B 1 146 ? 76.178  105.725 89.661  1.00 110.34 ? 146 SER B CB  1 
ATOM   5427  O OG  . SER B 1 146 ? 77.221  104.923 89.154  1.00 111.83 ? 146 SER B OG  1 
ATOM   5428  N N   . GLY B 1 147 ? 73.989  108.283 89.008  1.00 107.54 ? 147 GLY B N   1 
ATOM   5429  C CA  . GLY B 1 147 ? 72.936  109.110 89.614  1.00 107.60 ? 147 GLY B CA  1 
ATOM   5430  C C   . GLY B 1 147 ? 73.057  109.284 91.134  1.00 108.39 ? 147 GLY B C   1 
ATOM   5431  O O   . GLY B 1 147 ? 72.047  109.423 91.826  1.00 108.18 ? 147 GLY B O   1 
ATOM   5432  N N   . ASN B 1 148 ? 74.276  109.238 91.677  1.00 107.57 ? 148 ASN B N   1 
ATOM   5433  C CA  . ASN B 1 148 ? 74.500  109.288 93.149  1.00 107.49 ? 148 ASN B CA  1 
ATOM   5434  C C   . ASN B 1 148 ? 74.121  110.660 93.711  1.00 107.05 ? 148 ASN B C   1 
ATOM   5435  O O   . ASN B 1 148 ? 74.663  111.670 93.225  1.00 105.15 ? 148 ASN B O   1 
ATOM   5436  C CB  . ASN B 1 148 ? 75.951  108.943 93.494  1.00 107.11 ? 148 ASN B CB  1 
ATOM   5437  C CG  . ASN B 1 148 ? 76.266  109.042 94.972  1.00 106.35 ? 148 ASN B CG  1 
ATOM   5438  O OD1 . ASN B 1 148 ? 75.366  109.069 95.808  1.00 105.86 ? 148 ASN B OD1 1 
ATOM   5439  N ND2 . ASN B 1 148 ? 77.546  109.087 95.304  1.00 105.53 ? 148 ASN B ND2 1 
ATOM   5440  N N   . PRO B 1 149 ? 73.221  110.749 94.719  1.00 107.28 ? 149 PRO B N   1 
ATOM   5441  C CA  . PRO B 1 149 ? 72.900  112.032 95.347  1.00 107.01 ? 149 PRO B CA  1 
ATOM   5442  C C   . PRO B 1 149 ? 74.110  112.604 96.100  1.00 106.96 ? 149 PRO B C   1 
ATOM   5443  O O   . PRO B 1 149 ? 74.280  113.808 96.080  1.00 106.34 ? 149 PRO B O   1 
ATOM   5444  C CB  . PRO B 1 149 ? 71.792  111.693 96.358  1.00 106.71 ? 149 PRO B CB  1 
ATOM   5445  C CG  . PRO B 1 149 ? 71.239  110.369 95.881  1.00 106.63 ? 149 PRO B CG  1 
ATOM   5446  C CD  . PRO B 1 149 ? 72.431  109.650 95.289  1.00 106.23 ? 149 PRO B CD  1 
ATOM   5447  N N   . LYS B 1 150 ? 74.913  111.744 96.736  1.00 105.24 ? 150 LYS B N   1 
ATOM   5448  C CA  . LYS B 1 150 ? 76.034  112.256 97.545  1.00 103.39 ? 150 LYS B CA  1 
ATOM   5449  C C   . LYS B 1 150 ? 77.331  112.120 96.750  1.00 103.07 ? 150 LYS B C   1 
ATOM   5450  O O   . LYS B 1 150 ? 78.089  111.166 96.937  1.00 103.30 ? 150 LYS B O   1 
ATOM   5451  C CB  . LYS B 1 150 ? 76.094  111.509 98.889  1.00 102.20 ? 150 LYS B CB  1 
ATOM   5452  C CG  . LYS B 1 150 ? 74.884  111.801 99.783  1.00 102.41 ? 150 LYS B CG  1 
ATOM   5453  C CD  . LYS B 1 150 ? 74.966  111.021 101.095 1.00 103.25 ? 150 LYS B CD  1 
ATOM   5454  C CE  . LYS B 1 150 ? 73.765  111.329 101.986 1.00 103.31 ? 150 LYS B CE  1 
ATOM   5455  N NZ  . LYS B 1 150 ? 73.773  110.532 103.223 1.00 103.56 ? 150 LYS B NZ  1 
ATOM   5456  N N   . LEU B 1 151 ? 77.548  113.047 95.816  1.00 96.15  ? 151 LEU B N   1 
ATOM   5457  C CA  . LEU B 1 151 ? 78.586  112.950 94.785  1.00 96.38  ? 151 LEU B CA  1 
ATOM   5458  C C   . LEU B 1 151 ? 79.976  112.642 95.364  1.00 94.37  ? 151 LEU B C   1 
ATOM   5459  O O   . LEU B 1 151 ? 80.407  113.239 96.352  1.00 93.23  ? 151 LEU B O   1 
ATOM   5460  C CB  . LEU B 1 151 ? 78.630  114.248 93.955  1.00 95.56  ? 151 LEU B CB  1 
ATOM   5461  C CG  . LEU B 1 151 ? 77.361  114.564 93.148  1.00 96.59  ? 151 LEU B CG  1 
ATOM   5462  C CD1 . LEU B 1 151 ? 77.483  115.950 92.530  1.00 95.10  ? 151 LEU B CD1 1 
ATOM   5463  C CD2 . LEU B 1 151 ? 77.129  113.564 92.018  1.00 96.82  ? 151 LEU B CD2 1 
ATOM   5464  N N   . LEU B 1 152 ? 80.699  111.735 94.708  1.00 87.55  ? 152 LEU B N   1 
ATOM   5465  C CA  . LEU B 1 152 ? 81.996  111.200 95.132  1.00 87.00  ? 152 LEU B CA  1 
ATOM   5466  C C   . LEU B 1 152 ? 83.059  112.290 95.328  1.00 86.63  ? 152 LEU B C   1 
ATOM   5467  O O   . LEU B 1 152 ? 83.896  112.187 96.219  1.00 86.90  ? 152 LEU B O   1 
ATOM   5468  C CB  . LEU B 1 152 ? 82.426  110.178 94.064  1.00 87.73  ? 152 LEU B CB  1 
ATOM   5469  C CG  . LEU B 1 152 ? 83.797  109.518 94.253  1.00 86.20  ? 152 LEU B CG  1 
ATOM   5470  C CD1 . LEU B 1 152 ? 83.838  108.648 95.503  1.00 86.08  ? 152 LEU B CD1 1 
ATOM   5471  C CD2 . LEU B 1 152 ? 84.108  108.663 93.029  1.00 87.20  ? 152 LEU B CD2 1 
ATOM   5472  N N   . VAL B 1 153 ? 83.003  113.363 94.536  1.00 77.36  ? 153 VAL B N   1 
ATOM   5473  C CA  . VAL B 1 153 ? 83.964  114.475 94.581  1.00 76.09  ? 153 VAL B CA  1 
ATOM   5474  C C   . VAL B 1 153 ? 83.970  115.224 95.927  1.00 74.36  ? 153 VAL B C   1 
ATOM   5475  O O   . VAL B 1 153 ? 85.006  115.731 96.343  1.00 73.12  ? 153 VAL B O   1 
ATOM   5476  C CB  . VAL B 1 153 ? 83.724  115.400 93.373  1.00 73.05  ? 153 VAL B CB  1 
ATOM   5477  C CG1 . VAL B 1 153 ? 82.487  116.285 93.519  1.00 74.16  ? 153 VAL B CG1 1 
ATOM   5478  C CG2 . VAL B 1 153 ? 84.942  116.269 93.082  1.00 71.94  ? 153 VAL B CG2 1 
ATOM   5479  N N   . ASN B 1 154 ? 82.840  115.225 96.643  1.00 72.56  ? 154 ASN B N   1 
ATOM   5480  C CA  . ASN B 1 154 ? 82.661  115.876 97.944  1.00 71.99  ? 154 ASN B CA  1 
ATOM   5481  C C   . ASN B 1 154 ? 82.552  114.881 99.111  1.00 73.30  ? 154 ASN B C   1 
ATOM   5482  O O   . ASN B 1 154 ? 82.216  115.274 100.230 1.00 73.55  ? 154 ASN B O   1 
ATOM   5483  C CB  . ASN B 1 154 ? 81.464  116.842 97.866  1.00 72.62  ? 154 ASN B CB  1 
ATOM   5484  C CG  . ASN B 1 154 ? 81.730  117.972 96.897  1.00 73.60  ? 154 ASN B CG  1 
ATOM   5485  O OD1 . ASN B 1 154 ? 82.835  118.468 96.814  1.00 74.96  ? 154 ASN B OD1 1 
ATOM   5486  N ND2 . ASN B 1 154 ? 80.769  118.400 96.119  1.00 73.67  ? 154 ASN B ND2 1 
ATOM   5487  N N   . ALA B 1 155 ? 82.836  113.600 98.878  1.00 70.02  ? 155 ALA B N   1 
ATOM   5488  C CA  . ALA B 1 155 ? 82.978  112.629 99.956  1.00 67.45  ? 155 ALA B CA  1 
ATOM   5489  C C   . ALA B 1 155 ? 84.165  113.012 100.855 1.00 68.85  ? 155 ALA B C   1 
ATOM   5490  O O   . ALA B 1 155 ? 85.180  113.531 100.386 1.00 67.66  ? 155 ALA B O   1 
ATOM   5491  C CB  . ALA B 1 155 ? 83.126  111.224 99.368  1.00 70.06  ? 155 ALA B CB  1 
ATOM   5492  N N   . GLN B 1 156 ? 84.034  112.755 102.152 1.00 63.39  ? 156 GLN B N   1 
ATOM   5493  C CA  . GLN B 1 156 ? 85.039  113.109 103.153 1.00 59.38  ? 156 GLN B CA  1 
ATOM   5494  C C   . GLN B 1 156 ? 85.296  111.944 104.109 1.00 62.55  ? 156 GLN B C   1 
ATOM   5495  O O   . GLN B 1 156 ? 84.404  111.123 104.331 1.00 65.46  ? 156 GLN B O   1 
ATOM   5496  C CB  . GLN B 1 156 ? 84.600  114.349 103.924 1.00 58.11  ? 156 GLN B CB  1 
ATOM   5497  C CG  . GLN B 1 156 ? 84.691  115.645 103.137 1.00 60.23  ? 156 GLN B CG  1 
ATOM   5498  C CD  . GLN B 1 156 ? 84.073  116.770 103.926 1.00 61.86  ? 156 GLN B CD  1 
ATOM   5499  O OE1 . GLN B 1 156 ? 82.950  116.667 104.411 1.00 60.25  ? 156 GLN B OE1 1 
ATOM   5500  N NE2 . GLN B 1 156 ? 84.816  117.852 104.081 1.00 60.86  ? 156 GLN B NE2 1 
ATOM   5501  N N   . CYS B 1 157 ? 86.475  111.896 104.723 1.00 60.25  ? 157 CYS B N   1 
ATOM   5502  C CA  . CYS B 1 157 ? 86.754  111.009 105.856 1.00 60.53  ? 157 CYS B CA  1 
ATOM   5503  C C   . CYS B 1 157 ? 85.856  111.340 107.069 1.00 63.97  ? 157 CYS B C   1 
ATOM   5504  O O   . CYS B 1 157 ? 85.405  112.477 107.234 1.00 65.44  ? 157 CYS B O   1 
ATOM   5505  C CB  . CYS B 1 157 ? 88.237  111.079 106.218 1.00 59.44  ? 157 CYS B CB  1 
ATOM   5506  S SG  . CYS B 1 157 ? 89.272  110.516 104.841 1.00 66.27  ? 157 CYS B SG  1 
ATOM   5507  N N   . THR B 1 158 ? 85.609  110.353 107.931 1.00 64.48  ? 158 THR B N   1 
ATOM   5508  C CA  . THR B 1 158 ? 84.522  110.370 108.932 1.00 63.84  ? 158 THR B CA  1 
ATOM   5509  C C   . THR B 1 158 ? 84.995  110.077 110.363 1.00 63.94  ? 158 THR B C   1 
ATOM   5510  O O   . THR B 1 158 ? 84.288  110.379 111.320 1.00 64.53  ? 158 THR B O   1 
ATOM   5511  C CB  . THR B 1 158 ? 83.440  109.354 108.512 1.00 63.89  ? 158 THR B CB  1 
ATOM   5512  O OG1 . THR B 1 158 ? 83.007  109.619 107.196 1.00 63.58  ? 158 THR B OG1 1 
ATOM   5513  C CG2 . THR B 1 158 ? 82.179  109.360 109.375 1.00 63.35  ? 158 THR B CG2 1 
ATOM   5514  N N   . ASP B 1 159 ? 86.185  109.505 110.550 1.00 59.73  ? 159 ASP B N   1 
ATOM   5515  C CA  . ASP B 1 159 ? 86.727  109.174 111.877 1.00 61.46  ? 159 ASP B CA  1 
ATOM   5516  C C   . ASP B 1 159 ? 87.171  110.406 112.685 1.00 60.26  ? 159 ASP B C   1 
ATOM   5517  O O   . ASP B 1 159 ? 87.378  111.487 112.145 1.00 63.11  ? 159 ASP B O   1 
ATOM   5518  C CB  . ASP B 1 159 ? 87.911  108.227 111.722 1.00 64.05  ? 159 ASP B CB  1 
ATOM   5519  C CG  . ASP B 1 159 ? 89.098  108.947 111.085 1.00 63.66  ? 159 ASP B CG  1 
ATOM   5520  O OD1 . ASP B 1 159 ? 89.105  109.088 109.845 1.00 62.13  ? 159 ASP B OD1 1 
ATOM   5521  O OD2 . ASP B 1 159 ? 89.977  109.386 111.856 1.00 61.39  ? 159 ASP B OD2 1 
ATOM   5522  N N   . GLU B 1 160 ? 87.388  110.236 113.991 1.00 58.47  ? 160 GLU B N   1 
ATOM   5523  C CA  . GLU B 1 160 ? 87.749  111.322 114.905 1.00 58.11  ? 160 GLU B CA  1 
ATOM   5524  C C   . GLU B 1 160 ? 89.035  112.082 114.525 1.00 60.35  ? 160 GLU B C   1 
ATOM   5525  O O   . GLU B 1 160 ? 89.130  113.278 114.793 1.00 60.48  ? 160 GLU B O   1 
ATOM   5526  C CB  . GLU B 1 160 ? 87.849  110.733 116.324 1.00 58.56  ? 160 GLU B CB  1 
ATOM   5527  C CG  . GLU B 1 160 ? 88.223  111.755 117.404 1.00 60.84  ? 160 GLU B CG  1 
ATOM   5528  C CD  . GLU B 1 160 ? 88.049  111.241 118.844 1.00 64.73  ? 160 GLU B CD  1 
ATOM   5529  O OE1 . GLU B 1 160 ? 87.879  110.025 119.071 1.00 62.53  ? 160 GLU B OE1 1 
ATOM   5530  O OE2 . GLU B 1 160 ? 88.094  112.065 119.773 1.00 64.50  ? 160 GLU B OE2 1 
ATOM   5531  N N   . PHE B 1 161 ? 90.027  111.440 113.900 1.00 52.76  ? 161 PHE B N   1 
ATOM   5532  C CA  . PHE B 1 161 ? 91.283  112.101 113.541 1.00 48.94  ? 161 PHE B CA  1 
ATOM   5533  C C   . PHE B 1 161 ? 91.218  112.801 112.193 1.00 50.48  ? 161 PHE B C   1 
ATOM   5534  O O   . PHE B 1 161 ? 91.681  113.939 112.106 1.00 52.55  ? 161 PHE B O   1 
ATOM   5535  C CB  . PHE B 1 161 ? 92.469  111.139 113.627 1.00 45.27  ? 161 PHE B CB  1 
ATOM   5536  C CG  . PHE B 1 161 ? 93.034  111.104 115.028 1.00 51.87  ? 161 PHE B CG  1 
ATOM   5537  C CD1 . PHE B 1 161 ? 92.399  110.356 116.034 1.00 53.50  ? 161 PHE B CD1 1 
ATOM   5538  C CD2 . PHE B 1 161 ? 94.143  111.906 115.348 1.00 51.46  ? 161 PHE B CD2 1 
ATOM   5539  C CE1 . PHE B 1 161 ? 92.873  110.412 117.355 1.00 54.39  ? 161 PHE B CE1 1 
ATOM   5540  C CE2 . PHE B 1 161 ? 94.617  111.963 116.666 1.00 53.28  ? 161 PHE B CE2 1 
ATOM   5541  C CZ  . PHE B 1 161 ? 93.979  111.215 117.672 1.00 55.25  ? 161 PHE B CZ  1 
ATOM   5542  N N   . TYR B 1 162 ? 90.624  112.190 111.170 1.00 46.24  ? 162 TYR B N   1 
ATOM   5543  C CA  . TYR B 1 162 ? 90.636  112.745 109.816 1.00 42.24  ? 162 TYR B CA  1 
ATOM   5544  C C   . TYR B 1 162 ? 89.295  113.323 109.338 1.00 49.28  ? 162 TYR B C   1 
ATOM   5545  O O   . TYR B 1 162 ? 89.160  113.621 108.157 1.00 49.20  ? 162 TYR B O   1 
ATOM   5546  C CB  . TYR B 1 162 ? 91.285  111.767 108.830 1.00 46.28  ? 162 TYR B CB  1 
ATOM   5547  C CG  . TYR B 1 162 ? 92.613  111.225 109.322 1.00 48.50  ? 162 TYR B CG  1 
ATOM   5548  C CD1 . TYR B 1 162 ? 93.738  112.073 109.376 1.00 47.06  ? 162 TYR B CD1 1 
ATOM   5549  C CD2 . TYR B 1 162 ? 92.708  109.911 109.802 1.00 49.83  ? 162 TYR B CD2 1 
ATOM   5550  C CE1 . TYR B 1 162 ? 94.943  111.606 109.919 1.00 45.25  ? 162 TYR B CE1 1 
ATOM   5551  C CE2 . TYR B 1 162 ? 93.917  109.439 110.350 1.00 45.66  ? 162 TYR B CE2 1 
ATOM   5552  C CZ  . TYR B 1 162 ? 95.031  110.294 110.414 1.00 44.97  ? 162 TYR B CZ  1 
ATOM   5553  O OH  . TYR B 1 162 ? 96.187  109.857 110.967 1.00 50.00  ? 162 TYR B OH  1 
ATOM   5554  N N   . GLN B 1 163 ? 88.312  113.537 110.224 1.00 51.48  ? 163 GLN B N   1 
ATOM   5555  C CA  . GLN B 1 163 ? 86.988  114.062 109.866 1.00 51.99  ? 163 GLN B CA  1 
ATOM   5556  C C   . GLN B 1 163 ? 87.043  115.265 108.908 1.00 52.81  ? 163 GLN B C   1 
ATOM   5557  O O   . GLN B 1 163 ? 87.732  116.253 109.159 1.00 55.12  ? 163 GLN B O   1 
ATOM   5558  C CB  . GLN B 1 163 ? 86.201  114.432 111.132 1.00 52.23  ? 163 GLN B CB  1 
ATOM   5559  C CG  . GLN B 1 163 ? 84.737  114.773 110.823 1.00 54.51  ? 163 GLN B CG  1 
ATOM   5560  C CD  . GLN B 1 163 ? 83.873  114.889 112.072 1.00 57.59  ? 163 GLN B CD  1 
ATOM   5561  O OE1 . GLN B 1 163 ? 84.340  115.043 113.190 1.00 55.68  ? 163 GLN B OE1 1 
ATOM   5562  N NE2 . GLN B 1 163 ? 82.572  114.824 111.932 1.00 56.54  ? 163 GLN B NE2 1 
ATOM   5563  N N   . GLY B 1 164 ? 86.291  115.191 107.814 1.00 52.46  ? 164 GLY B N   1 
ATOM   5564  C CA  . GLY B 1 164 ? 86.161  116.275 106.844 1.00 48.54  ? 164 GLY B CA  1 
ATOM   5565  C C   . GLY B 1 164 ? 87.285  116.376 105.810 1.00 47.22  ? 164 GLY B C   1 
ATOM   5566  O O   . GLY B 1 164 ? 87.188  117.187 104.892 1.00 54.57  ? 164 GLY B O   1 
ATOM   5567  N N   . HIS B 1 165 ? 88.261  115.478 105.884 1.00 44.24  ? 165 HIS B N   1 
ATOM   5568  C CA  . HIS B 1 165 ? 89.356  115.422 104.881 1.00 42.67  ? 165 HIS B CA  1 
ATOM   5569  C C   . HIS B 1 165 ? 88.753  115.008 103.550 1.00 48.32  ? 165 HIS B C   1 
ATOM   5570  O O   . HIS B 1 165 ? 87.829  114.218 103.577 1.00 54.20  ? 165 HIS B O   1 
ATOM   5571  C CB  . HIS B 1 165 ? 90.457  114.479 105.349 1.00 48.71  ? 165 HIS B CB  1 
ATOM   5572  C CG  . HIS B 1 165 ? 91.711  114.500 104.548 1.00 48.72  ? 165 HIS B CG  1 
ATOM   5573  N ND1 . HIS B 1 165 ? 92.233  115.655 104.027 1.00 50.04  ? 165 HIS B ND1 1 
ATOM   5574  C CD2 . HIS B 1 165 ? 92.560  113.513 104.206 1.00 47.28  ? 165 HIS B CD2 1 
ATOM   5575  C CE1 . HIS B 1 165 ? 93.344  115.378 103.384 1.00 49.19  ? 165 HIS B CE1 1 
ATOM   5576  N NE2 . HIS B 1 165 ? 93.569  114.075 103.481 1.00 45.32  ? 165 HIS B NE2 1 
ATOM   5577  N N   . SER B 1 166 ? 89.294  115.481 102.433 1.00 47.04  ? 166 SER B N   1 
ATOM   5578  C CA  . SER B 1 166 ? 88.660  115.281 101.123 1.00 46.49  ? 166 SER B CA  1 
ATOM   5579  C C   . SER B 1 166 ? 89.676  115.134 99.992  1.00 47.33  ? 166 SER B C   1 
ATOM   5580  O O   . SER B 1 166 ? 90.843  115.493 100.135 1.00 49.33  ? 166 SER B O   1 
ATOM   5581  C CB  . SER B 1 166 ? 87.689  116.433 100.829 1.00 51.74  ? 166 SER B CB  1 
ATOM   5582  O OG  . SER B 1 166 ? 88.370  117.598 100.411 1.00 52.60  ? 166 SER B OG  1 
ATOM   5583  N N   . ALA B 1 167 ? 89.244  114.643 98.829  1.00 47.91  ? 167 ALA B N   1 
ATOM   5584  C CA  . ALA B 1 167 ? 90.116  114.502 97.666  1.00 49.85  ? 167 ALA B CA  1 
ATOM   5585  C C   . ALA B 1 167 ? 90.760  115.831 97.224  1.00 49.78  ? 167 ALA B C   1 
ATOM   5586  O O   . ALA B 1 167 ? 91.904  115.835 96.781  1.00 48.28  ? 167 ALA B O   1 
ATOM   5587  C CB  . ALA B 1 167 ? 89.294  113.873 96.535  1.00 49.79  ? 167 ALA B CB  1 
ATOM   5588  N N   . LEU B 1 168 ? 90.075  116.967 97.404  1.00 47.31  ? 168 LEU B N   1 
ATOM   5589  C CA  . LEU B 1 168 ? 90.619  118.292 97.094  1.00 47.78  ? 168 LEU B CA  1 
ATOM   5590  C C   . LEU B 1 168 ? 91.760  118.693 98.042  1.00 42.89  ? 168 LEU B C   1 
ATOM   5591  O O   . LEU B 1 168 ? 92.785  119.186 97.585  1.00 42.13  ? 168 LEU B O   1 
ATOM   5592  C CB  . LEU B 1 168 ? 89.464  119.307 97.077  1.00 47.83  ? 168 LEU B CB  1 
ATOM   5593  C CG  . LEU B 1 168 ? 89.894  120.748 96.749  1.00 47.91  ? 168 LEU B CG  1 
ATOM   5594  C CD1 . LEU B 1 168 ? 90.563  120.873 95.383  1.00 42.36  ? 168 LEU B CD1 1 
ATOM   5595  C CD2 . LEU B 1 168 ? 88.677  121.665 96.755  1.00 47.90  ? 168 LEU B CD2 1 
ATOM   5596  N N   . HIS B 1 169 ? 91.643  118.417 99.343  1.00 37.43  ? 169 HIS B N   1 
ATOM   5597  C CA  . HIS B 1 169 ? 92.755  118.596 100.280 1.00 37.14  ? 169 HIS B CA  1 
ATOM   5598  C C   . HIS B 1 169 ? 93.965  117.744 99.893  1.00 41.28  ? 169 HIS B C   1 
ATOM   5599  O O   . HIS B 1 169 ? 95.093  118.273 99.948  1.00 41.83  ? 169 HIS B O   1 
ATOM   5600  C CB  . HIS B 1 169 ? 92.295  118.260 101.707 1.00 38.00  ? 169 HIS B CB  1 
ATOM   5601  C CG  . HIS B 1 169 ? 91.381  119.275 102.311 1.00 40.71  ? 169 HIS B CG  1 
ATOM   5602  N ND1 . HIS B 1 169 ? 90.097  118.963 102.716 1.00 38.21  ? 169 HIS B ND1 1 
ATOM   5603  C CD2 . HIS B 1 169 ? 91.559  120.584 102.590 1.00 37.10  ? 169 HIS B CD2 1 
ATOM   5604  C CE1 . HIS B 1 169 ? 89.521  120.039 103.215 1.00 37.16  ? 169 HIS B CE1 1 
ATOM   5605  N NE2 . HIS B 1 169 ? 90.399  121.047 103.150 1.00 40.97  ? 169 HIS B NE2 1 
ATOM   5606  N N   . ILE B 1 170 ? 93.747  116.487 99.495  1.00 45.07  ? 170 ILE B N   1 
ATOM   5607  C CA  . ILE B 1 170 ? 94.825  115.602 99.029  1.00 40.02  ? 170 ILE B CA  1 
ATOM   5608  C C   . ILE B 1 170 ? 95.465  116.140 97.745  1.00 43.81  ? 170 ILE B C   1 
ATOM   5609  O O   . ILE B 1 170 ? 96.688  116.196 97.670  1.00 44.41  ? 170 ILE B O   1 
ATOM   5610  C CB  . ILE B 1 170 ? 94.341  114.148 98.857  1.00 47.81  ? 170 ILE B CB  1 
ATOM   5611  C CG1 . ILE B 1 170 ? 93.740  113.589 100.161 1.00 44.88  ? 170 ILE B CG1 1 
ATOM   5612  C CG2 . ILE B 1 170 ? 95.500  113.235 98.428  1.00 45.86  ? 170 ILE B CG2 1 
ATOM   5613  C CD1 . ILE B 1 170 ? 92.985  112.273 99.976  1.00 46.62  ? 170 ILE B CD1 1 
ATOM   5614  N N   . ALA B 1 171 ? 94.686  116.575 96.750  1.00 42.00  ? 171 ALA B N   1 
ATOM   5615  C CA  . ALA B 1 171 ? 95.221  117.129 95.507  1.00 39.18  ? 171 ALA B CA  1 
ATOM   5616  C C   . ALA B 1 171 ? 96.088  118.378 95.746  1.00 43.51  ? 171 ALA B C   1 
ATOM   5617  O O   . ALA B 1 171 ? 97.151  118.524 95.143  1.00 41.92  ? 171 ALA B O   1 
ATOM   5618  C CB  . ALA B 1 171 ? 94.051  117.443 94.573  1.00 40.49  ? 171 ALA B CB  1 
ATOM   5619  N N   . ILE B 1 172 ? 95.656  119.253 96.661  1.00 46.49  ? 172 ILE B N   1 
ATOM   5620  C CA  . ILE B 1 172 ? 96.411  120.440 97.063  1.00 39.84  ? 172 ILE B CA  1 
ATOM   5621  C C   . ILE B 1 172 ? 97.706  120.033 97.764  1.00 42.36  ? 172 ILE B C   1 
ATOM   5622  O O   . ILE B 1 172 ? 98.766  120.453 97.323  1.00 43.71  ? 172 ILE B O   1 
ATOM   5623  C CB  . ILE B 1 172 ? 95.542  121.388 97.912  1.00 40.89  ? 172 ILE B CB  1 
ATOM   5624  C CG1 . ILE B 1 172 ? 94.393  121.932 97.041  1.00 42.53  ? 172 ILE B CG1 1 
ATOM   5625  C CG2 . ILE B 1 172 ? 96.351  122.561 98.486  1.00 34.68  ? 172 ILE B CG2 1 
ATOM   5626  C CD1 . ILE B 1 172 ? 93.310  122.652 97.823  1.00 40.21  ? 172 ILE B CD1 1 
ATOM   5627  N N   . GLU B 1 173 ? 97.682  119.179 98.785  1.00 40.71  ? 173 GLU B N   1 
ATOM   5628  C CA  . GLU B 1 173 ? 98.912  118.738 99.468  1.00 38.66  ? 173 GLU B CA  1 
ATOM   5629  C C   . GLU B 1 173 ? 99.857  117.936 98.551  1.00 44.94  ? 173 GLU B C   1 
ATOM   5630  O O   . GLU B 1 173 ? 101.075 118.085 98.643  1.00 46.37  ? 173 GLU B O   1 
ATOM   5631  C CB  . GLU B 1 173 ? 98.525  117.979 100.744 1.00 44.81  ? 173 GLU B CB  1 
ATOM   5632  C CG  . GLU B 1 173 ? 99.614  117.138 101.432 1.00 46.59  ? 173 GLU B CG  1 
ATOM   5633  C CD  . GLU B 1 173 ? 100.996 117.779 101.589 1.00 49.52  ? 173 GLU B CD  1 
ATOM   5634  O OE1 . GLU B 1 173 ? 101.088 119.022 101.728 1.00 51.02  ? 173 GLU B OE1 1 
ATOM   5635  O OE2 . GLU B 1 173 ? 101.983 117.010 101.629 1.00 46.27  ? 173 GLU B OE2 1 
ATOM   5636  N N   . LYS B 1 174 ? 99.350  117.147 97.596  1.00 48.54  ? 174 LYS B N   1 
ATOM   5637  C CA  . LYS B 1 174 ? 100.159 116.491 96.553  1.00 44.59  ? 174 LYS B CA  1 
ATOM   5638  C C   . LYS B 1 174 ? 100.671 117.442 95.457  1.00 47.17  ? 174 LYS B C   1 
ATOM   5639  O O   . LYS B 1 174 ? 101.363 116.996 94.546  1.00 50.48  ? 174 LYS B O   1 
ATOM   5640  C CB  . LYS B 1 174 ? 99.403  115.280 95.983  1.00 46.75  ? 174 LYS B CB  1 
ATOM   5641  C CG  . LYS B 1 174 ? 99.305  114.100 96.973  1.00 48.95  ? 174 LYS B CG  1 
ATOM   5642  C CD  . LYS B 1 174 ? 100.659 113.407 97.178  1.00 47.01  ? 174 LYS B CD  1 
ATOM   5643  C CE  . LYS B 1 174 ? 100.576 112.267 98.199  1.00 48.20  ? 174 LYS B CE  1 
ATOM   5644  N NZ  . LYS B 1 174 ? 101.927 111.739 98.515  1.00 50.28  ? 174 LYS B NZ  1 
ATOM   5645  N N   . ARG B 1 175 ? 100.380 118.746 95.560  1.00 46.26  ? 175 ARG B N   1 
ATOM   5646  C CA  . ARG B 1 175 ? 100.864 119.854 94.709  1.00 40.97  ? 175 ARG B CA  1 
ATOM   5647  C C   . ARG B 1 175 ? 100.472 119.761 93.228  1.00 45.43  ? 175 ARG B C   1 
ATOM   5648  O O   . ARG B 1 175 ? 101.142 120.344 92.378  1.00 48.21  ? 175 ARG B O   1 
ATOM   5649  C CB  . ARG B 1 175 ? 102.368 120.128 94.937  1.00 42.41  ? 175 ARG B CB  1 
ATOM   5650  C CG  . ARG B 1 175 ? 102.745 120.294 96.412  1.00 42.95  ? 175 ARG B CG  1 
ATOM   5651  C CD  . ARG B 1 175 ? 104.212 120.682 96.636  1.00 41.98  ? 175 ARG B CD  1 
ATOM   5652  N NE  . ARG B 1 175 ? 104.518 122.080 96.272  1.00 46.21  ? 175 ARG B NE  1 
ATOM   5653  C CZ  . ARG B 1 175 ? 104.412 123.151 97.036  1.00 48.84  ? 175 ARG B CZ  1 
ATOM   5654  N NH1 . ARG B 1 175 ? 104.850 124.303 96.635  1.00 46.57  ? 175 ARG B NH1 1 
ATOM   5655  N NH2 . ARG B 1 175 ? 103.853 123.103 98.205  1.00 45.51  ? 175 ARG B NH2 1 
ATOM   5656  N N   . SER B 1 176 ? 99.387  119.059 92.901  1.00 53.84  ? 176 SER B N   1 
ATOM   5657  C CA  . SER B 1 176 ? 98.903  118.941 91.520  1.00 55.41  ? 176 SER B CA  1 
ATOM   5658  C C   . SER B 1 176 ? 97.816  119.968 91.210  1.00 59.60  ? 176 SER B C   1 
ATOM   5659  O O   . SER B 1 176 ? 96.634  119.759 91.482  1.00 62.21  ? 176 SER B O   1 
ATOM   5660  C CB  . SER B 1 176 ? 98.433  117.518 91.219  1.00 57.59  ? 176 SER B CB  1 
ATOM   5661  O OG  . SER B 1 176 ? 97.942  117.464 89.891  1.00 60.39  ? 176 SER B OG  1 
ATOM   5662  N N   . LEU B 1 177 ? 98.200  121.079 90.579  1.00 53.30  ? 177 LEU B N   1 
ATOM   5663  C CA  . LEU B 1 177 ? 97.244  122.043 90.040  1.00 54.95  ? 177 LEU B CA  1 
ATOM   5664  C C   . LEU B 1 177 ? 96.368  121.420 88.942  1.00 58.77  ? 177 LEU B C   1 
ATOM   5665  O O   . LEU B 1 177 ? 95.181  121.717 88.873  1.00 60.49  ? 177 LEU B O   1 
ATOM   5666  C CB  . LEU B 1 177 ? 98.014  123.278 89.556  1.00 58.41  ? 177 LEU B CB  1 
ATOM   5667  C CG  . LEU B 1 177 ? 97.144  124.356 88.890  1.00 58.50  ? 177 LEU B CG  1 
ATOM   5668  C CD1 . LEU B 1 177 ? 96.067  124.898 89.826  1.00 55.66  ? 177 LEU B CD1 1 
ATOM   5669  C CD2 . LEU B 1 177 ? 98.040  125.512 88.467  1.00 55.77  ? 177 LEU B CD2 1 
ATOM   5670  N N   . GLN B 1 178 ? 96.907  120.501 88.138  1.00 60.63  ? 178 GLN B N   1 
ATOM   5671  C CA  . GLN B 1 178 ? 96.147  119.716 87.162  1.00 57.39  ? 178 GLN B CA  1 
ATOM   5672  C C   . GLN B 1 178 ? 95.000  118.946 87.824  1.00 59.61  ? 178 GLN B C   1 
ATOM   5673  O O   . GLN B 1 178 ? 93.870  118.978 87.347  1.00 60.93  ? 178 GLN B O   1 
ATOM   5674  C CB  . GLN B 1 178 ? 97.076  118.727 86.431  1.00 60.02  ? 178 GLN B CB  1 
ATOM   5675  C CG  . GLN B 1 178 ? 98.193  119.368 85.591  1.00 60.93  ? 178 GLN B CG  1 
ATOM   5676  C CD  . GLN B 1 178 ? 99.510  119.594 86.331  1.00 63.10  ? 178 GLN B CD  1 
ATOM   5677  O OE1 . GLN B 1 178 ? 99.566  119.864 87.521  1.00 63.21  ? 178 GLN B OE1 1 
ATOM   5678  N NE2 . GLN B 1 178 ? 100.630 119.514 85.649  1.00 62.38  ? 178 GLN B NE2 1 
ATOM   5679  N N   . CYS B 1 179 ? 95.264  118.280 88.949  1.00 57.63  ? 179 CYS B N   1 
ATOM   5680  C CA  . CYS B 1 179 ? 94.250  117.540 89.689  1.00 58.37  ? 179 CYS B CA  1 
ATOM   5681  C C   . CYS B 1 179 ? 93.260  118.469 90.413  1.00 61.15  ? 179 CYS B C   1 
ATOM   5682  O O   . CYS B 1 179 ? 92.058  118.213 90.387  1.00 58.28  ? 179 CYS B O   1 
ATOM   5683  C CB  . CYS B 1 179 ? 94.972  116.577 90.636  1.00 57.64  ? 179 CYS B CB  1 
ATOM   5684  S SG  . CYS B 1 179 ? 93.796  115.412 91.355  1.00 65.71  ? 179 CYS B SG  1 
ATOM   5685  N N   . VAL B 1 180 ? 93.718  119.593 90.983  1.00 56.94  ? 180 VAL B N   1 
ATOM   5686  C CA  . VAL B 1 180 ? 92.833  120.613 91.575  1.00 55.94  ? 180 VAL B CA  1 
ATOM   5687  C C   . VAL B 1 180 ? 91.869  121.182 90.534  1.00 55.90  ? 180 VAL B C   1 
ATOM   5688  O O   . VAL B 1 180 ? 90.662  121.201 90.771  1.00 51.90  ? 180 VAL B O   1 
ATOM   5689  C CB  . VAL B 1 180 ? 93.643  121.736 92.255  1.00 56.80  ? 180 VAL B CB  1 
ATOM   5690  C CG1 . VAL B 1 180 ? 92.766  122.918 92.668  1.00 56.73  ? 180 VAL B CG1 1 
ATOM   5691  C CG2 . VAL B 1 180 ? 94.338  121.211 93.513  1.00 50.70  ? 180 VAL B CG2 1 
ATOM   5692  N N   . LYS B 1 181 ? 92.364  121.572 89.351  1.00 57.73  ? 181 LYS B N   1 
ATOM   5693  C CA  . LYS B 1 181 ? 91.534  122.010 88.226  1.00 54.72  ? 181 LYS B CA  1 
ATOM   5694  C C   . LYS B 1 181 ? 90.496  120.954 87.849  1.00 56.10  ? 181 LYS B C   1 
ATOM   5695  O O   . LYS B 1 181 ? 89.316  121.263 87.760  1.00 58.39  ? 181 LYS B O   1 
ATOM   5696  C CB  . LYS B 1 181 ? 92.412  122.338 87.010  1.00 54.77  ? 181 LYS B CB  1 
ATOM   5697  C CG  . LYS B 1 181 ? 93.149  123.671 87.156  1.00 57.95  ? 181 LYS B CG  1 
ATOM   5698  C CD  . LYS B 1 181 ? 94.034  123.951 85.943  1.00 55.32  ? 181 LYS B CD  1 
ATOM   5699  C CE  . LYS B 1 181 ? 94.671  125.335 86.065  1.00 58.46  ? 181 LYS B CE  1 
ATOM   5700  N NZ  . LYS B 1 181 ? 95.423  125.700 84.845  1.00 59.62  ? 181 LYS B NZ  1 
ATOM   5701  N N   . LEU B 1 182 ? 90.923  119.703 87.681  1.00 62.48  ? 182 LEU B N   1 
ATOM   5702  C CA  . LEU B 1 182 ? 90.061  118.579 87.309  1.00 63.59  ? 182 LEU B CA  1 
ATOM   5703  C C   . LEU B 1 182 ? 88.937  118.340 88.334  1.00 64.68  ? 182 LEU B C   1 
ATOM   5704  O O   . LEU B 1 182 ? 87.783  118.161 87.952  1.00 65.73  ? 182 LEU B O   1 
ATOM   5705  C CB  . LEU B 1 182 ? 90.989  117.360 87.118  1.00 63.05  ? 182 LEU B CB  1 
ATOM   5706  C CG  . LEU B 1 182 ? 90.435  116.147 86.359  1.00 64.99  ? 182 LEU B CG  1 
ATOM   5707  C CD1 . LEU B 1 182 ? 91.604  115.208 86.081  1.00 65.72  ? 182 LEU B CD1 1 
ATOM   5708  C CD2 . LEU B 1 182 ? 89.386  115.359 87.130  1.00 64.85  ? 182 LEU B CD2 1 
ATOM   5709  N N   . LEU B 1 183 ? 89.247  118.385 89.629  1.00 62.07  ? 183 LEU B N   1 
ATOM   5710  C CA  . LEU B 1 183 ? 88.267  118.247 90.710  1.00 62.44  ? 183 LEU B CA  1 
ATOM   5711  C C   . LEU B 1 183 ? 87.296  119.436 90.775  1.00 62.36  ? 183 LEU B C   1 
ATOM   5712  O O   . LEU B 1 183 ? 86.085  119.239 90.867  1.00 62.52  ? 183 LEU B O   1 
ATOM   5713  C CB  . LEU B 1 183 ? 89.018  118.074 92.041  1.00 64.28  ? 183 LEU B CB  1 
ATOM   5714  C CG  . LEU B 1 183 ? 89.754  116.731 92.210  1.00 63.77  ? 183 LEU B CG  1 
ATOM   5715  C CD1 . LEU B 1 183 ? 90.623  116.805 93.459  1.00 59.74  ? 183 LEU B CD1 1 
ATOM   5716  C CD2 . LEU B 1 183 ? 88.799  115.558 92.390  1.00 63.64  ? 183 LEU B CD2 1 
ATOM   5717  N N   . VAL B 1 184 ? 87.793  120.673 90.691  1.00 65.58  ? 184 VAL B N   1 
ATOM   5718  C CA  . VAL B 1 184 ? 86.955  121.880 90.771  1.00 65.10  ? 184 VAL B CA  1 
ATOM   5719  C C   . VAL B 1 184 ? 86.048  122.028 89.542  1.00 66.00  ? 184 VAL B C   1 
ATOM   5720  O O   . VAL B 1 184 ? 84.866  122.324 89.696  1.00 66.98  ? 184 VAL B O   1 
ATOM   5721  C CB  . VAL B 1 184 ? 87.835  123.117 91.029  1.00 62.91  ? 184 VAL B CB  1 
ATOM   5722  C CG1 . VAL B 1 184 ? 87.072  124.435 90.893  1.00 61.25  ? 184 VAL B CG1 1 
ATOM   5723  C CG2 . VAL B 1 184 ? 88.397  123.065 92.457  1.00 61.08  ? 184 VAL B CG2 1 
ATOM   5724  N N   . GLU B 1 185 ? 86.533  121.708 88.339  1.00 64.04  ? 185 GLU B N   1 
ATOM   5725  C CA  . GLU B 1 185 ? 85.701  121.586 87.131  1.00 63.27  ? 185 GLU B CA  1 
ATOM   5726  C C   . GLU B 1 185 ? 84.542  120.590 87.284  1.00 67.14  ? 185 GLU B C   1 
ATOM   5727  O O   . GLU B 1 185 ? 83.492  120.762 86.667  1.00 68.44  ? 185 GLU B O   1 
ATOM   5728  C CB  . GLU B 1 185 ? 86.574  121.131 85.949  1.00 64.04  ? 185 GLU B CB  1 
ATOM   5729  C CG  . GLU B 1 185 ? 87.473  122.246 85.400  1.00 64.30  ? 185 GLU B CG  1 
ATOM   5730  C CD  . GLU B 1 185 ? 88.647  121.735 84.544  1.00 67.63  ? 185 GLU B CD  1 
ATOM   5731  O OE1 . GLU B 1 185 ? 88.627  120.576 84.073  1.00 67.54  ? 185 GLU B OE1 1 
ATOM   5732  O OE2 . GLU B 1 185 ? 89.579  122.531 84.280  1.00 67.10  ? 185 GLU B OE2 1 
ATOM   5733  N N   . ASN B 1 186 ? 84.710  119.550 88.107  1.00 67.55  ? 186 ASN B N   1 
ATOM   5734  C CA  . ASN B 1 186 ? 83.710  118.513 88.365  1.00 66.16  ? 186 ASN B CA  1 
ATOM   5735  C C   . ASN B 1 186 ? 82.877  118.739 89.643  1.00 67.95  ? 186 ASN B C   1 
ATOM   5736  O O   . ASN B 1 186 ? 82.147  117.847 90.070  1.00 68.18  ? 186 ASN B O   1 
ATOM   5737  C CB  . ASN B 1 186 ? 84.392  117.141 88.303  1.00 67.82  ? 186 ASN B CB  1 
ATOM   5738  C CG  . ASN B 1 186 ? 84.606  116.724 86.867  1.00 69.56  ? 186 ASN B CG  1 
ATOM   5739  O OD1 . ASN B 1 186 ? 83.704  116.205 86.219  1.00 71.14  ? 186 ASN B OD1 1 
ATOM   5740  N ND2 . ASN B 1 186 ? 85.774  116.946 86.316  1.00 68.22  ? 186 ASN B ND2 1 
ATOM   5741  N N   . GLY B 1 187 ? 82.941  119.923 90.253  1.00 67.30  ? 187 GLY B N   1 
ATOM   5742  C CA  . GLY B 1 187 ? 82.073  120.293 91.375  1.00 65.30  ? 187 GLY B CA  1 
ATOM   5743  C C   . GLY B 1 187 ? 82.626  120.002 92.774  1.00 66.03  ? 187 GLY B C   1 
ATOM   5744  O O   . GLY B 1 187 ? 81.842  119.881 93.719  1.00 64.72  ? 187 GLY B O   1 
ATOM   5745  N N   . ALA B 1 188 ? 83.950  119.906 92.936  1.00 65.30  ? 188 ALA B N   1 
ATOM   5746  C CA  . ALA B 1 188 ? 84.575  119.902 94.259  1.00 62.54  ? 188 ALA B CA  1 
ATOM   5747  C C   . ALA B 1 188 ? 84.242  121.189 95.035  1.00 65.14  ? 188 ALA B C   1 
ATOM   5748  O O   . ALA B 1 188 ? 84.542  122.294 94.589  1.00 67.46  ? 188 ALA B O   1 
ATOM   5749  C CB  . ALA B 1 188 ? 86.089  119.738 94.120  1.00 61.67  ? 188 ALA B CB  1 
ATOM   5750  N N   . ASP B 1 189 ? 83.636  121.050 96.208  1.00 62.71  ? 189 ASP B N   1 
ATOM   5751  C CA  . ASP B 1 189 ? 83.339  122.159 97.107  1.00 57.50  ? 189 ASP B CA  1 
ATOM   5752  C C   . ASP B 1 189 ? 84.630  122.687 97.749  1.00 61.34  ? 189 ASP B C   1 
ATOM   5753  O O   . ASP B 1 189 ? 85.313  121.990 98.498  1.00 63.15  ? 189 ASP B O   1 
ATOM   5754  C CB  . ASP B 1 189 ? 82.308  121.714 98.155  1.00 56.93  ? 189 ASP B CB  1 
ATOM   5755  C CG  . ASP B 1 189 ? 81.912  122.836 99.127  1.00 63.87  ? 189 ASP B CG  1 
ATOM   5756  O OD1 . ASP B 1 189 ? 82.328  123.995 98.914  1.00 65.06  ? 189 ASP B OD1 1 
ATOM   5757  O OD2 . ASP B 1 189 ? 81.142  122.557 100.070 1.00 64.28  ? 189 ASP B OD2 1 
ATOM   5758  N N   . VAL B 1 190 ? 84.969  123.939 97.460  1.00 55.81  ? 190 VAL B N   1 
ATOM   5759  C CA  . VAL B 1 190 ? 86.190  124.584 97.947  1.00 52.62  ? 190 VAL B CA  1 
ATOM   5760  C C   . VAL B 1 190 ? 86.079  125.003 99.423  1.00 51.90  ? 190 VAL B C   1 
ATOM   5761  O O   . VAL B 1 190 ? 87.057  125.440 100.015 1.00 54.55  ? 190 VAL B O   1 
ATOM   5762  C CB  . VAL B 1 190 ? 86.595  125.739 97.006  1.00 53.18  ? 190 VAL B CB  1 
ATOM   5763  C CG1 . VAL B 1 190 ? 88.018  126.223 97.271  1.00 55.26  ? 190 VAL B CG1 1 
ATOM   5764  C CG2 . VAL B 1 190 ? 86.568  125.309 95.534  1.00 50.73  ? 190 VAL B CG2 1 
ATOM   5765  N N   . HIS B 1 191 ? 84.911  124.846 100.056 1.00 53.07  ? 191 HIS B N   1 
ATOM   5766  C CA  . HIS B 1 191 ? 84.659  125.232 101.450 1.00 51.70  ? 191 HIS B CA  1 
ATOM   5767  C C   . HIS B 1 191 ? 84.501  124.056 102.422 1.00 53.46  ? 191 HIS B C   1 
ATOM   5768  O O   . HIS B 1 191 ? 83.946  124.226 103.508 1.00 55.90  ? 191 HIS B O   1 
ATOM   5769  C CB  . HIS B 1 191 ? 83.441  126.168 101.501 1.00 55.35  ? 191 HIS B CB  1 
ATOM   5770  C CG  . HIS B 1 191 ? 83.619  127.401 100.679 1.00 56.76  ? 191 HIS B CG  1 
ATOM   5771  N ND1 . HIS B 1 191 ? 84.112  128.578 101.209 1.00 53.20  ? 191 HIS B ND1 1 
ATOM   5772  C CD2 . HIS B 1 191 ? 83.386  127.643 99.370  1.00 54.86  ? 191 HIS B CD2 1 
ATOM   5773  C CE1 . HIS B 1 191 ? 84.170  129.494 100.263 1.00 54.53  ? 191 HIS B CE1 1 
ATOM   5774  N NE2 . HIS B 1 191 ? 83.730  128.943 99.125  1.00 56.23  ? 191 HIS B NE2 1 
ATOM   5775  N N   . LEU B 1 192 ? 84.971  122.852 102.078 1.00 55.46  ? 192 LEU B N   1 
ATOM   5776  C CA  . LEU B 1 192 ? 84.994  121.718 103.013 1.00 50.97  ? 192 LEU B CA  1 
ATOM   5777  C C   . LEU B 1 192 ? 86.033  121.929 104.124 1.00 50.27  ? 192 LEU B C   1 
ATOM   5778  O O   . LEU B 1 192 ? 87.188  122.238 103.839 1.00 51.79  ? 192 LEU B O   1 
ATOM   5779  C CB  . LEU B 1 192 ? 85.291  120.415 102.249 1.00 50.96  ? 192 LEU B CB  1 
ATOM   5780  C CG  . LEU B 1 192 ? 84.249  120.044 101.182 1.00 55.37  ? 192 LEU B CG  1 
ATOM   5781  C CD1 . LEU B 1 192 ? 84.674  118.768 100.462 1.00 53.04  ? 192 LEU B CD1 1 
ATOM   5782  C CD2 . LEU B 1 192 ? 82.863  119.824 101.778 1.00 53.25  ? 192 LEU B CD2 1 
ATOM   5783  N N   . ARG B 1 193 ? 85.668  121.616 105.380 1.00 46.32  ? 193 ARG B N   1 
ATOM   5784  C CA  . ARG B 1 193 ? 86.608  121.840 106.522 1.00 45.39  ? 193 ARG B CA  1 
ATOM   5785  C C   . ARG B 1 193 ? 87.210  120.563 107.098 1.00 45.01  ? 193 ARG B C   1 
ATOM   5786  O O   . ARG B 1 193 ? 86.506  119.877 107.866 1.00 49.62  ? 193 ARG B O   1 
ATOM   5787  C CB  . ARG B 1 193 ? 85.954  122.488 107.757 1.00 51.26  ? 193 ARG B CB  1 
ATOM   5788  C CG  . ARG B 1 193 ? 85.763  124.009 107.718 1.00 44.87  ? 193 ARG B CG  1 
ATOM   5789  C CD  . ARG B 1 193 ? 84.663  124.450 106.754 1.00 48.83  ? 193 ARG B CD  1 
ATOM   5790  N NE  . ARG B 1 193 ? 84.632  125.901 106.635 1.00 52.18  ? 193 ARG B NE  1 
ATOM   5791  C CZ  . ARG B 1 193 ? 83.778  126.582 105.879 1.00 49.70  ? 193 ARG B CZ  1 
ATOM   5792  N NH1 . ARG B 1 193 ? 83.837  127.902 105.840 1.00 48.34  ? 193 ARG B NH1 1 
ATOM   5793  N NH2 . ARG B 1 193 ? 82.871  125.942 105.164 1.00 48.53  ? 193 ARG B NH2 1 
ATOM   5794  N N   . ALA B 1 194 ? 88.453  120.260 106.749 1.00 37.89  ? 194 ALA B N   1 
ATOM   5795  C CA  . ALA B 1 194 ? 89.200  119.184 107.390 1.00 32.82  ? 194 ALA B CA  1 
ATOM   5796  C C   . ALA B 1 194 ? 89.377  119.517 108.877 1.00 39.43  ? 194 ALA B C   1 
ATOM   5797  O O   . ALA B 1 194 ? 90.238  120.306 109.247 1.00 41.45  ? 194 ALA B O   1 
ATOM   5798  C CB  . ALA B 1 194 ? 90.534  119.010 106.664 1.00 30.93  ? 194 ALA B CB  1 
ATOM   5799  N N   . CYS B 1 195 ? 88.511  118.985 109.738 1.00 41.11  ? 195 CYS B N   1 
ATOM   5800  C CA  . CYS B 1 195 ? 88.305  119.447 111.116 1.00 40.11  ? 195 CYS B CA  1 
ATOM   5801  C C   . CYS B 1 195 ? 88.562  118.376 112.195 1.00 49.12  ? 195 CYS B C   1 
ATOM   5802  O O   . CYS B 1 195 ? 88.518  118.688 113.387 1.00 51.56  ? 195 CYS B O   1 
ATOM   5803  C CB  . CYS B 1 195 ? 86.882  120.015 111.213 1.00 43.03  ? 195 CYS B CB  1 
ATOM   5804  S SG  . CYS B 1 195 ? 85.651  118.740 110.824 1.00 60.88  ? 195 CYS B SG  1 
ATOM   5805  N N   . GLY B 1 196 ? 88.846  117.126 111.808 1.00 44.92  ? 196 GLY B N   1 
ATOM   5806  C CA  . GLY B 1 196 ? 89.220  116.061 112.737 1.00 41.01  ? 196 GLY B CA  1 
ATOM   5807  C C   . GLY B 1 196 ? 90.488  116.363 113.546 1.00 40.83  ? 196 GLY B C   1 
ATOM   5808  O O   . GLY B 1 196 ? 91.243  117.283 113.243 1.00 44.42  ? 196 GLY B O   1 
ATOM   5809  N N   . ARG B 1 197 ? 90.746  115.583 114.601 1.00 40.01  ? 197 ARG B N   1 
ATOM   5810  C CA  . ARG B 1 197 ? 91.807  115.850 115.581 1.00 42.34  ? 197 ARG B CA  1 
ATOM   5811  C C   . ARG B 1 197 ? 93.212  115.977 114.984 1.00 41.54  ? 197 ARG B C   1 
ATOM   5812  O O   . ARG B 1 197 ? 94.029  116.698 115.541 1.00 42.13  ? 197 ARG B O   1 
ATOM   5813  C CB  . ARG B 1 197 ? 91.744  114.771 116.679 1.00 42.99  ? 197 ARG B CB  1 
ATOM   5814  C CG  . ARG B 1 197 ? 92.622  115.038 117.909 1.00 41.25  ? 197 ARG B CG  1 
ATOM   5815  C CD  . ARG B 1 197 ? 92.290  116.385 118.552 1.00 41.36  ? 197 ARG B CD  1 
ATOM   5816  N NE  . ARG B 1 197 ? 93.030  116.608 119.799 1.00 49.80  ? 197 ARG B NE  1 
ATOM   5817  C CZ  . ARG B 1 197 ? 93.065  117.737 120.478 1.00 51.78  ? 197 ARG B CZ  1 
ATOM   5818  N NH1 . ARG B 1 197 ? 93.765  117.819 121.567 1.00 46.12  ? 197 ARG B NH1 1 
ATOM   5819  N NH2 . ARG B 1 197 ? 92.412  118.798 120.098 1.00 48.39  ? 197 ARG B NH2 1 
ATOM   5820  N N   . PHE B 1 198 ? 93.511  115.354 113.847 1.00 36.53  ? 198 PHE B N   1 
ATOM   5821  C CA  . PHE B 1 198 ? 94.788  115.541 113.152 1.00 34.34  ? 198 PHE B CA  1 
ATOM   5822  C C   . PHE B 1 198 ? 94.973  116.963 112.592 1.00 36.80  ? 198 PHE B C   1 
ATOM   5823  O O   . PHE B 1 198 ? 96.089  117.454 112.476 1.00 31.80  ? 198 PHE B O   1 
ATOM   5824  C CB  . PHE B 1 198 ? 94.880  114.517 112.018 1.00 29.26  ? 198 PHE B CB  1 
ATOM   5825  C CG  . PHE B 1 198 ? 96.156  114.651 111.222 1.00 32.98  ? 198 PHE B CG  1 
ATOM   5826  C CD1 . PHE B 1 198 ? 97.383  114.325 111.812 1.00 31.96  ? 198 PHE B CD1 1 
ATOM   5827  C CD2 . PHE B 1 198 ? 96.121  115.196 109.930 1.00 31.66  ? 198 PHE B CD2 1 
ATOM   5828  C CE1 . PHE B 1 198 ? 98.575  114.560 111.119 1.00 25.65  ? 198 PHE B CE1 1 
ATOM   5829  C CE2 . PHE B 1 198 ? 97.316  115.422 109.229 1.00 28.53  ? 198 PHE B CE2 1 
ATOM   5830  C CZ  . PHE B 1 198 ? 98.540  115.105 109.819 1.00 31.14  ? 198 PHE B CZ  1 
ATOM   5831  N N   . PHE B 1 199 ? 93.884  117.643 112.249 1.00 39.37  ? 199 PHE B N   1 
ATOM   5832  C CA  . PHE B 1 199 ? 93.904  118.969 111.640 1.00 28.27  ? 199 PHE B CA  1 
ATOM   5833  C C   . PHE B 1 199 ? 93.770  120.117 112.642 1.00 34.31  ? 199 PHE B C   1 
ATOM   5834  O O   . PHE B 1 199 ? 93.868  121.278 112.261 1.00 38.75  ? 199 PHE B O   1 
ATOM   5835  C CB  . PHE B 1 199 ? 92.789  119.017 110.604 1.00 24.88  ? 199 PHE B CB  1 
ATOM   5836  C CG  . PHE B 1 199 ? 92.916  117.944 109.559 1.00 30.56  ? 199 PHE B CG  1 
ATOM   5837  C CD1 . PHE B 1 199 ? 93.981  117.987 108.649 1.00 31.32  ? 199 PHE B CD1 1 
ATOM   5838  C CD2 . PHE B 1 199 ? 91.984  116.896 109.500 1.00 32.22  ? 199 PHE B CD2 1 
ATOM   5839  C CE1 . PHE B 1 199 ? 94.096  117.006 107.651 1.00 31.58  ? 199 PHE B CE1 1 
ATOM   5840  C CE2 . PHE B 1 199 ? 92.105  115.922 108.504 1.00 30.84  ? 199 PHE B CE2 1 
ATOM   5841  C CZ  . PHE B 1 199 ? 93.154  115.975 107.581 1.00 29.86  ? 199 PHE B CZ  1 
ATOM   5842  N N   . GLN B 1 200 ? 93.531  119.821 113.914 1.00 38.32  ? 200 GLN B N   1 
ATOM   5843  C CA  . GLN B 1 200 ? 93.479  120.792 115.002 1.00 33.63  ? 200 GLN B CA  1 
ATOM   5844  C C   . GLN B 1 200 ? 94.889  121.128 115.501 1.00 38.74  ? 200 GLN B C   1 
ATOM   5845  O O   . GLN B 1 200 ? 95.807  120.326 115.375 1.00 40.13  ? 200 GLN B O   1 
ATOM   5846  C CB  . GLN B 1 200 ? 92.600  120.237 116.131 1.00 36.97  ? 200 GLN B CB  1 
ATOM   5847  C CG  . GLN B 1 200 ? 91.135  120.068 115.696 1.00 37.38  ? 200 GLN B CG  1 
ATOM   5848  C CD  . GLN B 1 200 ? 90.292  119.276 116.687 1.00 41.48  ? 200 GLN B CD  1 
ATOM   5849  O OE1 . GLN B 1 200 ? 90.636  119.089 117.847 1.00 44.86  ? 200 GLN B OE1 1 
ATOM   5850  N NE2 . GLN B 1 200 ? 89.168  118.749 116.260 1.00 38.94  ? 200 GLN B NE2 1 
ATOM   5851  N N   . LYS B 1 201 ? 95.084  122.300 116.111 1.00 42.97  ? 201 LYS B N   1 
ATOM   5852  C CA  . LYS B 1 201 ? 96.348  122.667 116.760 1.00 40.51  ? 201 LYS B CA  1 
ATOM   5853  C C   . LYS B 1 201 ? 96.374  122.127 118.196 1.00 46.35  ? 201 LYS B C   1 
ATOM   5854  O O   . LYS B 1 201 ? 95.512  122.463 119.001 1.00 50.81  ? 201 LYS B O   1 
ATOM   5855  C CB  . LYS B 1 201 ? 96.519  124.191 116.677 1.00 45.47  ? 201 LYS B CB  1 
ATOM   5856  C CG  . LYS B 1 201 ? 97.846  124.729 117.224 1.00 47.23  ? 201 LYS B CG  1 
ATOM   5857  C CD  . LYS B 1 201 ? 99.086  124.190 116.509 1.00 50.49  ? 201 LYS B CD  1 
ATOM   5858  C CE  . LYS B 1 201 ? 100.332 124.879 117.065 1.00 52.40  ? 201 LYS B CE  1 
ATOM   5859  N NZ  . LYS B 1 201 ? 101.573 124.369 116.454 1.00 51.61  ? 201 LYS B NZ  1 
ATOM   5860  N N   . HIS B 1 202 ? 97.356  121.289 118.521 1.00 42.54  ? 202 HIS B N   1 
ATOM   5861  C CA  . HIS B 1 202 ? 97.617  120.731 119.854 1.00 42.16  ? 202 HIS B CA  1 
ATOM   5862  C C   . HIS B 1 202 ? 99.065  120.245 119.946 1.00 46.50  ? 202 HIS B C   1 
ATOM   5863  O O   . HIS B 1 202 ? 99.803  120.293 118.962 1.00 48.39  ? 202 HIS B O   1 
ATOM   5864  C CB  . HIS B 1 202 ? 96.621  119.603 120.159 1.00 42.71  ? 202 HIS B CB  1 
ATOM   5865  C CG  . HIS B 1 202 ? 96.556  118.556 119.098 1.00 45.17  ? 202 HIS B CG  1 
ATOM   5866  N ND1 . HIS B 1 202 ? 97.487  117.539 119.006 1.00 47.80  ? 202 HIS B ND1 1 
ATOM   5867  C CD2 . HIS B 1 202 ? 95.681  118.361 118.089 1.00 44.55  ? 202 HIS B CD2 1 
ATOM   5868  C CE1 . HIS B 1 202 ? 97.188  116.764 117.984 1.00 43.22  ? 202 HIS B CE1 1 
ATOM   5869  N NE2 . HIS B 1 202 ? 96.082  117.247 117.405 1.00 39.99  ? 202 HIS B NE2 1 
ATOM   5870  N N   . GLN B 1 203 ? 99.498  119.798 121.133 1.00 57.48  ? 203 GLN B N   1 
ATOM   5871  C CA  . GLN B 1 203 ? 100.932 119.421 121.347 1.00 57.27  ? 203 GLN B CA  1 
ATOM   5872  C C   . GLN B 1 203 ? 101.262 118.065 120.706 1.00 56.93  ? 203 GLN B C   1 
ATOM   5873  O O   . GLN B 1 203 ? 102.463 117.787 120.526 1.00 56.55  ? 203 GLN B O   1 
ATOM   5874  C CB  . GLN B 1 203 ? 101.230 119.449 122.851 1.00 54.65  ? 203 GLN B CB  1 
ATOM   5875  C CG  . GLN B 1 203 ? 101.172 120.868 123.440 1.00 55.07  ? 203 GLN B CG  1 
ATOM   5876  C CD  . GLN B 1 203 ? 101.485 120.884 124.916 1.00 60.45  ? 203 GLN B CD  1 
ATOM   5877  O OE1 . GLN B 1 203 ? 101.457 121.927 125.566 1.00 61.84  ? 203 GLN B OE1 1 
ATOM   5878  N NE2 . GLN B 1 203 ? 101.785 119.716 125.460 1.00 58.07  ? 203 GLN B NE2 1 
ATOM   5879  N N   . GLY B 1 204 ? 100.252 117.261 120.375 1.00 49.41  ? 204 GLY B N   1 
ATOM   5880  C CA  . GLY B 1 204 ? 100.408 115.947 119.756 1.00 46.63  ? 204 GLY B CA  1 
ATOM   5881  C C   . GLY B 1 204 ? 100.703 115.980 118.257 1.00 45.77  ? 204 GLY B C   1 
ATOM   5882  O O   . GLY B 1 204 ? 101.156 116.979 117.701 1.00 52.01  ? 204 GLY B O   1 
ATOM   5883  N N   . THR B 1 205 ? 100.474 114.858 117.584 1.00 45.69  ? 205 THR B N   1 
ATOM   5884  C CA  . THR B 1 205 ? 100.737 114.697 116.148 1.00 46.05  ? 205 THR B CA  1 
ATOM   5885  C C   . THR B 1 205 ? 99.599  115.301 115.320 1.00 42.92  ? 205 THR B C   1 
ATOM   5886  O O   . THR B 1 205 ? 98.491  114.769 115.261 1.00 43.37  ? 205 THR B O   1 
ATOM   5887  C CB  . THR B 1 205 ? 101.046 113.224 115.805 1.00 46.43  ? 205 THR B CB  1 
ATOM   5888  O OG1 . THR B 1 205 ? 100.085 112.340 116.331 1.00 53.17  ? 205 THR B OG1 1 
ATOM   5889  C CG2 . THR B 1 205 ? 102.383 112.822 116.406 1.00 45.87  ? 205 THR B CG2 1 
ATOM   5890  N N   . CYS B 1 206 ? 99.854  116.455 114.701 1.00 36.44  ? 206 CYS B N   1 
ATOM   5891  C CA  . CYS B 1 206 ? 98.864  117.217 113.946 1.00 31.21  ? 206 CYS B CA  1 
ATOM   5892  C C   . CYS B 1 206 ? 99.478  118.119 112.869 1.00 28.99  ? 206 CYS B C   1 
ATOM   5893  O O   . CYS B 1 206 ? 100.667 118.436 112.881 1.00 33.97  ? 206 CYS B O   1 
ATOM   5894  C CB  . CYS B 1 206 ? 98.002  118.033 114.918 1.00 34.69  ? 206 CYS B CB  1 
ATOM   5895  S SG  . CYS B 1 206 ? 98.858  119.464 115.618 1.00 30.25  ? 206 CYS B SG  1 
ATOM   5896  N N   . PHE B 1 207 ? 98.629  118.578 111.958 1.00 26.59  ? 207 PHE B N   1 
ATOM   5897  C CA  . PHE B 1 207 ? 98.927  119.564 110.929 1.00 22.30  ? 207 PHE B CA  1 
ATOM   5898  C C   . PHE B 1 207 ? 97.771  120.564 110.850 1.00 22.78  ? 207 PHE B C   1 
ATOM   5899  O O   . PHE B 1 207 ? 96.825  120.385 110.092 1.00 30.79  ? 207 PHE B O   1 
ATOM   5900  C CB  . PHE B 1 207 ? 99.189  118.828 109.608 1.00 24.89  ? 207 PHE B CB  1 
ATOM   5901  C CG  . PHE B 1 207 ? 99.432  119.671 108.370 1.00 23.88  ? 207 PHE B CG  1 
ATOM   5902  C CD1 . PHE B 1 207 ? 100.037 120.939 108.424 1.00 26.38  ? 207 PHE B CD1 1 
ATOM   5903  C CD2 . PHE B 1 207 ? 99.099  119.129 107.119 1.00 30.94  ? 207 PHE B CD2 1 
ATOM   5904  C CE1 . PHE B 1 207 ? 100.296 121.649 107.241 1.00 21.95  ? 207 PHE B CE1 1 
ATOM   5905  C CE2 . PHE B 1 207 ? 99.349  119.840 105.936 1.00 24.61  ? 207 PHE B CE2 1 
ATOM   5906  C CZ  . PHE B 1 207 ? 99.957  121.102 105.998 1.00 28.13  ? 207 PHE B CZ  1 
ATOM   5907  N N   . TYR B 1 208 ? 97.835  121.619 111.660 1.00 22.04  ? 208 TYR B N   1 
ATOM   5908  C CA  . TYR B 1 208 ? 96.951  122.771 111.518 1.00 28.34  ? 208 TYR B CA  1 
ATOM   5909  C C   . TYR B 1 208 ? 97.411  123.686 110.375 1.00 30.84  ? 208 TYR B C   1 
ATOM   5910  O O   . TYR B 1 208 ? 98.554  124.127 110.340 1.00 34.14  ? 208 TYR B O   1 
ATOM   5911  C CB  . TYR B 1 208 ? 96.840  123.532 112.847 1.00 24.31  ? 208 TYR B CB  1 
ATOM   5912  C CG  . TYR B 1 208 ? 95.877  124.697 112.776 1.00 24.46  ? 208 TYR B CG  1 
ATOM   5913  C CD1 . TYR B 1 208 ? 94.498  124.472 112.892 1.00 27.59  ? 208 TYR B CD1 1 
ATOM   5914  C CD2 . TYR B 1 208 ? 96.348  125.990 112.487 1.00 28.51  ? 208 TYR B CD2 1 
ATOM   5915  C CE1 . TYR B 1 208 ? 93.582  125.519 112.695 1.00 32.19  ? 208 TYR B CE1 1 
ATOM   5916  C CE2 . TYR B 1 208 ? 95.433  127.036 112.276 1.00 26.46  ? 208 TYR B CE2 1 
ATOM   5917  C CZ  . TYR B 1 208 ? 94.051  126.803 112.381 1.00 32.07  ? 208 TYR B CZ  1 
ATOM   5918  O OH  . TYR B 1 208 ? 93.178  127.808 112.137 1.00 37.95  ? 208 TYR B OH  1 
ATOM   5919  N N   . PHE B 1 209 ? 96.499  124.029 109.470 1.00 27.39  ? 209 PHE B N   1 
ATOM   5920  C CA  . PHE B 1 209 ? 96.714  124.924 108.329 1.00 29.65  ? 209 PHE B CA  1 
ATOM   5921  C C   . PHE B 1 209 ? 95.490  125.823 108.110 1.00 27.13  ? 209 PHE B C   1 
ATOM   5922  O O   . PHE B 1 209 ? 95.226  126.294 107.011 1.00 38.68  ? 209 PHE B O   1 
ATOM   5923  C CB  . PHE B 1 209 ? 97.028  124.084 107.077 1.00 25.78  ? 209 PHE B CB  1 
ATOM   5924  C CG  . PHE B 1 209 ? 96.013  122.998 106.738 1.00 23.16  ? 209 PHE B CG  1 
ATOM   5925  C CD1 . PHE B 1 209 ? 94.781  123.303 106.126 1.00 24.16  ? 209 PHE B CD1 1 
ATOM   5926  C CD2 . PHE B 1 209 ? 96.312  121.659 107.036 1.00 22.88  ? 209 PHE B CD2 1 
ATOM   5927  C CE1 . PHE B 1 209 ? 93.849  122.285 105.853 1.00 27.74  ? 209 PHE B CE1 1 
ATOM   5928  C CE2 . PHE B 1 209 ? 95.402  120.640 106.721 1.00 29.89  ? 209 PHE B CE2 1 
ATOM   5929  C CZ  . PHE B 1 209 ? 94.160  120.951 106.148 1.00 27.63  ? 209 PHE B CZ  1 
ATOM   5930  N N   . GLY B 1 210 ? 94.697  126.046 109.150 1.00 23.23  ? 210 GLY B N   1 
ATOM   5931  C CA  . GLY B 1 210 ? 93.279  126.305 108.968 1.00 27.90  ? 210 GLY B CA  1 
ATOM   5932  C C   . GLY B 1 210 ? 92.608  124.952 108.746 1.00 41.48  ? 210 GLY B C   1 
ATOM   5933  O O   . GLY B 1 210 ? 93.162  123.916 109.117 1.00 52.52  ? 210 GLY B O   1 
ATOM   5934  N N   . GLU B 1 211 ? 91.448  124.920 108.102 1.00 36.84  ? 211 GLU B N   1 
ATOM   5935  C CA  . GLU B 1 211 ? 90.781  123.647 107.782 1.00 31.99  ? 211 GLU B CA  1 
ATOM   5936  C C   . GLU B 1 211 ? 90.363  123.552 106.311 1.00 33.69  ? 211 GLU B C   1 
ATOM   5937  O O   . GLU B 1 211 ? 89.917  122.513 105.844 1.00 35.37  ? 211 GLU B O   1 
ATOM   5938  C CB  . GLU B 1 211 ? 89.578  123.463 108.715 1.00 32.02  ? 211 GLU B CB  1 
ATOM   5939  C CG  . GLU B 1 211 ? 90.000  123.410 110.191 1.00 30.49  ? 211 GLU B CG  1 
ATOM   5940  C CD  . GLU B 1 211 ? 88.813  123.299 111.151 1.00 40.22  ? 211 GLU B CD  1 
ATOM   5941  O OE1 . GLU B 1 211 ? 87.663  123.623 110.774 1.00 43.91  ? 211 GLU B OE1 1 
ATOM   5942  O OE2 . GLU B 1 211 ? 89.036  122.951 112.327 1.00 42.80  ? 211 GLU B OE2 1 
ATOM   5943  N N   . LEU B 1 212 ? 90.492  124.648 105.563 1.00 38.64  ? 212 LEU B N   1 
ATOM   5944  C CA  . LEU B 1 212 ? 89.922  124.642 104.185 1.00 33.70  ? 212 LEU B CA  1 
ATOM   5945  C C   . LEU B 1 212 ? 91.000  124.569 103.102 1.00 33.76  ? 212 LEU B C   1 
ATOM   5946  O O   . LEU B 1 212 ? 92.161  124.929 103.382 1.00 40.09  ? 212 LEU B O   1 
ATOM   5947  C CB  . LEU B 1 212 ? 89.056  125.897 104.012 1.00 38.55  ? 212 LEU B CB  1 
ATOM   5948  C CG  . LEU B 1 212 ? 87.833  125.979 104.923 1.00 41.52  ? 212 LEU B CG  1 
ATOM   5949  C CD1 . LEU B 1 212 ? 88.251  126.176 106.374 1.00 40.34  ? 212 LEU B CD1 1 
ATOM   5950  C CD2 . LEU B 1 212 ? 86.904  127.100 104.484 1.00 38.83  ? 212 LEU B CD2 1 
ATOM   5951  N N   . PRO B 1 213 ? 90.645  124.120 101.878 1.00 36.26  ? 213 PRO B N   1 
ATOM   5952  C CA  . PRO B 1 213 ? 91.594  124.066 100.765 1.00 37.61  ? 213 PRO B CA  1 
ATOM   5953  C C   . PRO B 1 213 ? 92.383  125.374 100.623 1.00 37.40  ? 213 PRO B C   1 
ATOM   5954  O O   . PRO B 1 213 ? 93.598  125.305 100.569 1.00 35.74  ? 213 PRO B O   1 
ATOM   5955  C CB  . PRO B 1 213 ? 90.673  123.882 99.551  1.00 40.37  ? 213 PRO B CB  1 
ATOM   5956  C CG  . PRO B 1 213 ? 89.506  123.093 100.099 1.00 32.93  ? 213 PRO B CG  1 
ATOM   5957  C CD  . PRO B 1 213 ? 89.319  123.620 101.506 1.00 33.68  ? 213 PRO B CD  1 
ATOM   5958  N N   . LEU B 1 214 ? 91.695  126.519 100.562 1.00 34.17  ? 214 LEU B N   1 
ATOM   5959  C CA  . LEU B 1 214 ? 92.441  127.759 100.333 1.00 32.87  ? 214 LEU B CA  1 
ATOM   5960  C C   . LEU B 1 214 ? 93.508  128.011 101.406 1.00 26.47  ? 214 LEU B C   1 
ATOM   5961  O O   . LEU B 1 214 ? 94.626  128.408 101.090 1.00 32.33  ? 214 LEU B O   1 
ATOM   5962  C CB  . LEU B 1 214 ? 91.458  128.935 100.229 1.00 38.33  ? 214 LEU B CB  1 
ATOM   5963  C CG  . LEU B 1 214 ? 92.146  130.284 99.957  1.00 33.63  ? 214 LEU B CG  1 
ATOM   5964  C CD1 . LEU B 1 214 ? 92.760  130.324 98.566  1.00 34.10  ? 214 LEU B CD1 1 
ATOM   5965  C CD2 . LEU B 1 214 ? 91.154  131.426 100.079 1.00 32.84  ? 214 LEU B CD2 1 
ATOM   5966  N N   . SER B 1 215 ? 93.184  127.753 102.670 1.00 20.77  ? 215 SER B N   1 
ATOM   5967  C CA  . SER B 1 215 ? 94.138  127.898 103.766 1.00 14.71  ? 215 SER B CA  1 
ATOM   5968  C C   . SER B 1 215 ? 95.260  126.871 103.685 1.00 22.18  ? 215 SER B C   1 
ATOM   5969  O O   . SER B 1 215 ? 96.412  127.234 103.884 1.00 23.95  ? 215 SER B O   1 
ATOM   5970  C CB  . SER B 1 215 ? 93.447  127.830 105.121 1.00 26.47  ? 215 SER B CB  1 
ATOM   5971  O OG  . SER B 1 215 ? 92.323  128.686 105.151 1.00 34.27  ? 215 SER B OG  1 
ATOM   5972  N N   . LEU B 1 216 ? 94.972  125.632 103.279 1.00 36.54  ? 216 LEU B N   1 
ATOM   5973  C CA  . LEU B 1 216 ? 95.987  124.642 102.937 1.00 23.43  ? 216 LEU B CA  1 
ATOM   5974  C C   . LEU B 1 216 ? 96.896  125.162 101.821 1.00 28.15  ? 216 LEU B C   1 
ATOM   5975  O O   . LEU B 1 216 ? 98.092  125.276 102.039 1.00 38.38  ? 216 LEU B O   1 
ATOM   5976  C CB  . LEU B 1 216 ? 95.299  123.318 102.578 1.00 26.52  ? 216 LEU B CB  1 
ATOM   5977  C CG  . LEU B 1 216 ? 96.249  122.156 102.246 1.00 27.29  ? 216 LEU B CG  1 
ATOM   5978  C CD1 . LEU B 1 216 ? 97.184  121.771 103.387 1.00 23.30  ? 216 LEU B CD1 1 
ATOM   5979  C CD2 . LEU B 1 216 ? 95.400  120.946 101.891 1.00 25.38  ? 216 LEU B CD2 1 
ATOM   5980  N N   . ALA B 1 217 ? 96.351  125.563 100.669 1.00 26.06  ? 217 ALA B N   1 
ATOM   5981  C CA  . ALA B 1 217 ? 97.142  126.061 99.546  1.00 22.88  ? 217 ALA B CA  1 
ATOM   5982  C C   . ALA B 1 217 ? 98.027  127.271 99.907  1.00 31.61  ? 217 ALA B C   1 
ATOM   5983  O O   . ALA B 1 217 ? 99.158  127.382 99.437  1.00 31.82  ? 217 ALA B O   1 
ATOM   5984  C CB  . ALA B 1 217 ? 96.185  126.393 98.398  1.00 26.51  ? 217 ALA B CB  1 
ATOM   5985  N N   . ALA B 1 218 ? 97.546  128.170 100.771 1.00 32.97  ? 218 ALA B N   1 
ATOM   5986  C CA  . ALA B 1 218 ? 98.331  129.274 101.303 1.00 24.68  ? 218 ALA B CA  1 
ATOM   5987  C C   . ALA B 1 218 ? 99.423  128.800 102.276 1.00 24.51  ? 218 ALA B C   1 
ATOM   5988  O O   . ALA B 1 218 ? 100.574 129.213 102.159 1.00 29.46  ? 218 ALA B O   1 
ATOM   5989  C CB  . ALA B 1 218 ? 97.380  130.264 101.966 1.00 27.04  ? 218 ALA B CB  1 
ATOM   5990  N N   . CYS B 1 219 ? 99.104  127.906 103.210 1.00 28.54  ? 219 CYS B N   1 
ATOM   5991  C CA  . CYS B 1 219 ? 100.060 127.410 104.200 1.00 28.74  ? 219 CYS B CA  1 
ATOM   5992  C C   . CYS B 1 219 ? 101.159 126.521 103.601 1.00 33.23  ? 219 CYS B C   1 
ATOM   5993  O O   . CYS B 1 219 ? 102.265 126.463 104.130 1.00 32.12  ? 219 CYS B O   1 
ATOM   5994  C CB  . CYS B 1 219 ? 99.321  126.693 105.339 1.00 32.38  ? 219 CYS B CB  1 
ATOM   5995  S SG  . CYS B 1 219 ? 98.212  127.816 106.259 1.00 36.50  ? 219 CYS B SG  1 
ATOM   5996  N N   . THR B 1 220 ? 100.883 125.971 102.411 1.00 40.44  ? 220 THR B N   1 
ATOM   5997  C CA  . THR B 1 220 ? 101.892 125.148 101.691 1.00 33.81  ? 220 THR B CA  1 
ATOM   5998  C C   . THR B 1 220 ? 102.659 126.020 100.686 1.00 38.69  ? 220 THR B C   1 
ATOM   5999  O O   . THR B 1 220 ? 103.640 125.501 100.122 1.00 48.03  ? 220 THR B O   1 
ATOM   6000  C CB  . THR B 1 220 ? 101.225 123.962 100.982 1.00 38.80  ? 220 THR B CB  1 
ATOM   6001  O OG1 . THR B 1 220 ? 100.278 124.489 100.052 1.00 43.27  ? 220 THR B OG1 1 
ATOM   6002  C CG2 . THR B 1 220 ? 100.532 123.018 101.940 1.00 37.39  ? 220 THR B CG2 1 
ATOM   6003  N N   . LYS B 1 221 ? 102.210 127.259 100.439 1.00 41.73  ? 221 LYS B N   1 
ATOM   6004  C CA  . LYS B 1 221 ? 102.924 128.225 99.541  1.00 40.12  ? 221 LYS B CA  1 
ATOM   6005  C C   . LYS B 1 221 ? 102.635 127.930 98.057  1.00 43.09  ? 221 LYS B C   1 
ATOM   6006  O O   . LYS B 1 221 ? 103.474 128.294 97.209  1.00 43.36  ? 221 LYS B O   1 
ATOM   6007  C CB  . LYS B 1 221 ? 104.420 128.286 99.882  1.00 37.84  ? 221 LYS B CB  1 
ATOM   6008  C CG  . LYS B 1 221 ? 105.362 127.447 99.027  1.00 44.63  ? 221 LYS B CG  1 
ATOM   6009  C CD  . LYS B 1 221 ? 106.820 127.673 99.358  1.00 45.46  ? 221 LYS B CD  1 
ATOM   6010  C CE  . LYS B 1 221 ? 107.759 127.140 98.297  1.00 49.55  ? 221 LYS B CE  1 
ATOM   6011  N NZ  . LYS B 1 221 ? 109.179 127.324 98.679  1.00 50.93  ? 221 LYS B NZ  1 
ATOM   6012  N N   . GLN B 1 222 ? 101.474 127.350 97.744  1.00 44.99  ? 222 GLN B N   1 
ATOM   6013  C CA  . GLN B 1 222 ? 101.086 127.072 96.360  1.00 43.83  ? 222 GLN B CA  1 
ATOM   6014  C C   . GLN B 1 222 ? 100.331 128.258 95.760  1.00 40.13  ? 222 GLN B C   1 
ATOM   6015  O O   . GLN B 1 222 ? 99.112  128.235 95.612  1.00 41.93  ? 222 GLN B O   1 
ATOM   6016  C CB  . GLN B 1 222 ? 100.277 125.776 96.295  1.00 45.16  ? 222 GLN B CB  1 
ATOM   6017  C CG  . GLN B 1 222 ? 101.184 124.580 96.579  1.00 38.59  ? 222 GLN B CG  1 
ATOM   6018  C CD  . GLN B 1 222 ? 100.394 123.354 96.976  1.00 40.34  ? 222 GLN B CD  1 
ATOM   6019  O OE1 . GLN B 1 222 ? 100.576 122.801 98.042  1.00 47.11  ? 222 GLN B OE1 1 
ATOM   6020  N NE2 . GLN B 1 222 ? 99.484  122.886 96.164  1.00 45.84  ? 222 GLN B NE2 1 
ATOM   6021  N N   . TRP B 1 223 ? 101.056 129.323 95.436  1.00 41.89  ? 223 TRP B N   1 
ATOM   6022  C CA  . TRP B 1 223 ? 100.460 130.582 94.989  1.00 50.21  ? 223 TRP B CA  1 
ATOM   6023  C C   . TRP B 1 223 ? 99.649  130.453 93.688  1.00 50.27  ? 223 TRP B C   1 
ATOM   6024  O O   . TRP B 1 223 ? 98.634  131.116 93.521  1.00 50.28  ? 223 TRP B O   1 
ATOM   6025  C CB  . TRP B 1 223 ? 101.579 131.623 94.881  1.00 47.55  ? 223 TRP B CB  1 
ATOM   6026  C CG  . TRP B 1 223 ? 101.101 133.005 94.590  1.00 48.26  ? 223 TRP B CG  1 
ATOM   6027  C CD1 . TRP B 1 223 ? 101.438 133.754 93.516  1.00 50.98  ? 223 TRP B CD1 1 
ATOM   6028  C CD2 . TRP B 1 223 ? 100.183 133.819 95.377  1.00 51.71  ? 223 TRP B CD2 1 
ATOM   6029  N NE1 . TRP B 1 223 ? 100.786 134.970 93.583  1.00 52.41  ? 223 TRP B NE1 1 
ATOM   6030  C CE2 . TRP B 1 223 ? 99.986  135.058 94.701  1.00 53.70  ? 223 TRP B CE2 1 
ATOM   6031  C CE3 . TRP B 1 223 ? 99.481  133.628 96.585  1.00 48.93  ? 223 TRP B CE3 1 
ATOM   6032  C CZ2 . TRP B 1 223 ? 99.123  136.043 95.188  1.00 48.71  ? 223 TRP B CZ2 1 
ATOM   6033  C CZ3 . TRP B 1 223 ? 98.590  134.600 97.071  1.00 44.18  ? 223 TRP B CZ3 1 
ATOM   6034  C CH2 . TRP B 1 223 ? 98.385  135.786 96.353  1.00 50.56  ? 223 TRP B CH2 1 
ATOM   6035  N N   . ASP B 1 224 ? 100.039 129.537 92.801  1.00 50.09  ? 224 ASP B N   1 
ATOM   6036  C CA  . ASP B 1 224 ? 99.290  129.184 91.552  1.00 49.31  ? 224 ASP B CA  1 
ATOM   6037  C C   . ASP B 1 224 ? 98.017  128.371 91.856  1.00 49.15  ? 224 ASP B C   1 
ATOM   6038  O O   . ASP B 1 224 ? 97.077  128.485 91.046  1.00 48.67  ? 224 ASP B O   1 
ATOM   6039  C CB  . ASP B 1 224 ? 100.184 128.421 90.571  1.00 51.64  ? 224 ASP B CB  1 
ATOM   6040  C CG  . ASP B 1 224 ? 100.666 127.086 91.114  1.00 56.26  ? 224 ASP B CG  1 
ATOM   6041  O OD1 . ASP B 1 224 ? 100.433 126.824 92.311  1.00 54.71  ? 224 ASP B OD1 1 
ATOM   6042  O OD2 . ASP B 1 224 ? 101.265 126.320 90.335  1.00 57.67  ? 224 ASP B OD2 1 
ATOM   6043  N N   . VAL B 1 225 ? 97.945  127.602 92.946  1.00 48.37  ? 225 VAL B N   1 
ATOM   6044  C CA  . VAL B 1 225 ? 96.695  126.984 93.407  1.00 45.62  ? 225 VAL B CA  1 
ATOM   6045  C C   . VAL B 1 225 ? 95.801  128.012 94.101  1.00 48.98  ? 225 VAL B C   1 
ATOM   6046  O O   . VAL B 1 225 ? 94.596  128.012 93.876  1.00 48.56  ? 225 VAL B O   1 
ATOM   6047  C CB  . VAL B 1 225 ? 96.965  125.778 94.325  1.00 46.89  ? 225 VAL B CB  1 
ATOM   6048  C CG1 . VAL B 1 225 ? 95.676  125.185 94.888  1.00 46.82  ? 225 VAL B CG1 1 
ATOM   6049  C CG2 . VAL B 1 225 ? 97.683  124.655 93.573  1.00 45.09  ? 225 VAL B CG2 1 
ATOM   6050  N N   . VAL B 1 226 ? 96.370  128.918 94.901  1.00 47.35  ? 226 VAL B N   1 
ATOM   6051  C CA  . VAL B 1 226 ? 95.637  130.010 95.554  1.00 46.28  ? 226 VAL B CA  1 
ATOM   6052  C C   . VAL B 1 226 ? 94.908  130.885 94.532  1.00 45.28  ? 226 VAL B C   1 
ATOM   6053  O O   . VAL B 1 226 ? 93.696  131.058 94.639  1.00 46.38  ? 226 VAL B O   1 
ATOM   6054  C CB  . VAL B 1 226 ? 96.586  130.840 96.440  1.00 44.68  ? 226 VAL B CB  1 
ATOM   6055  C CG1 . VAL B 1 226 ? 95.986  132.165 96.902  1.00 47.51  ? 226 VAL B CG1 1 
ATOM   6056  C CG2 . VAL B 1 226 ? 96.990  130.060 97.688  1.00 41.76  ? 226 VAL B CG2 1 
ATOM   6057  N N   . THR B 1 227 ? 95.609  131.392 93.512  1.00 51.29  ? 227 THR B N   1 
ATOM   6058  C CA  . THR B 1 227 ? 94.961  132.204 92.474  1.00 51.12  ? 227 THR B CA  1 
ATOM   6059  C C   . THR B 1 227 ? 93.928  131.410 91.685  1.00 50.49  ? 227 THR B C   1 
ATOM   6060  O O   . THR B 1 227 ? 92.860  131.939 91.410  1.00 54.87  ? 227 THR B O   1 
ATOM   6061  C CB  . THR B 1 227 ? 95.960  132.858 91.514  1.00 53.14  ? 227 THR B CB  1 
ATOM   6062  O OG1 . THR B 1 227 ? 96.755  131.892 90.884  1.00 55.88  ? 227 THR B OG1 1 
ATOM   6063  C CG2 . THR B 1 227 ? 96.865  133.844 92.236  1.00 51.72  ? 227 THR B CG2 1 
ATOM   6064  N N   . TYR B 1 228 ? 94.159  130.133 91.376  1.00 48.60  ? 228 TYR B N   1 
ATOM   6065  C CA  . TYR B 1 228 ? 93.139  129.290 90.757  1.00 46.01  ? 228 TYR B CA  1 
ATOM   6066  C C   . TYR B 1 228 ? 91.900  129.113 91.644  1.00 46.16  ? 228 TYR B C   1 
ATOM   6067  O O   . TYR B 1 228 ? 90.778  129.363 91.203  1.00 49.22  ? 228 TYR B O   1 
ATOM   6068  C CB  . TYR B 1 228 ? 93.656  127.902 90.375  1.00 50.00  ? 228 TYR B CB  1 
ATOM   6069  C CG  . TYR B 1 228 ? 92.550  127.006 89.882  1.00 54.69  ? 228 TYR B CG  1 
ATOM   6070  C CD1 . TYR B 1 228 ? 92.102  127.070 88.573  1.00 52.37  ? 228 TYR B CD1 1 
ATOM   6071  C CD2 . TYR B 1 228 ? 91.897  126.143 90.745  1.00 50.90  ? 228 TYR B CD2 1 
ATOM   6072  C CE1 . TYR B 1 228 ? 91.058  126.277 88.127  1.00 48.91  ? 228 TYR B CE1 1 
ATOM   6073  C CE2 . TYR B 1 228 ? 90.854  125.342 90.317  1.00 45.62  ? 228 TYR B CE2 1 
ATOM   6074  C CZ  . TYR B 1 228 ? 90.432  125.410 89.004  1.00 51.33  ? 228 TYR B CZ  1 
ATOM   6075  O OH  . TYR B 1 228 ? 89.403  124.625 88.581  1.00 56.03  ? 228 TYR B OH  1 
ATOM   6076  N N   . LEU B 1 229 ? 92.062  128.727 92.909  1.00 50.38  ? 229 LEU B N   1 
ATOM   6077  C CA  . LEU B 1 229 ? 90.938  128.549 93.827  1.00 49.19  ? 229 LEU B CA  1 
ATOM   6078  C C   . LEU B 1 229 ? 90.141  129.844 93.999  1.00 54.21  ? 229 LEU B C   1 
ATOM   6079  O O   . LEU B 1 229 ? 88.923  129.780 94.071  1.00 54.88  ? 229 LEU B O   1 
ATOM   6080  C CB  . LEU B 1 229 ? 91.426  128.044 95.193  1.00 48.81  ? 229 LEU B CB  1 
ATOM   6081  C CG  . LEU B 1 229 ? 91.938  126.594 95.234  1.00 52.30  ? 229 LEU B CG  1 
ATOM   6082  C CD1 . LEU B 1 229 ? 92.353  126.267 96.665  1.00 46.38  ? 229 LEU B CD1 1 
ATOM   6083  C CD2 . LEU B 1 229 ? 90.897  125.568 94.785  1.00 51.42  ? 229 LEU B CD2 1 
ATOM   6084  N N   . LEU B 1 230 ? 90.798  131.002 94.029  1.00 52.98  ? 230 LEU B N   1 
ATOM   6085  C CA  . LEU B 1 230 ? 90.155  132.310 94.114  1.00 50.07  ? 230 LEU B CA  1 
ATOM   6086  C C   . LEU B 1 230 ? 89.472  132.754 92.807  1.00 53.51  ? 230 LEU B C   1 
ATOM   6087  O O   . LEU B 1 230 ? 88.350  133.252 92.848  1.00 56.90  ? 230 LEU B O   1 
ATOM   6088  C CB  . LEU B 1 230 ? 91.217  133.332 94.545  1.00 51.46  ? 230 LEU B CB  1 
ATOM   6089  C CG  . LEU B 1 230 ? 91.678  133.215 96.008  1.00 46.94  ? 230 LEU B CG  1 
ATOM   6090  C CD1 . LEU B 1 230 ? 92.871  134.131 96.260  1.00 46.96  ? 230 LEU B CD1 1 
ATOM   6091  C CD2 . LEU B 1 230 ? 90.579  133.609 96.982  1.00 45.33  ? 230 LEU B CD2 1 
ATOM   6092  N N   . GLU B 1 231 ? 90.125  132.609 91.656  1.00 59.08  ? 231 GLU B N   1 
ATOM   6093  C CA  . GLU B 1 231 ? 89.710  133.235 90.392  1.00 57.35  ? 231 GLU B CA  1 
ATOM   6094  C C   . GLU B 1 231 ? 88.964  132.317 89.407  1.00 60.43  ? 231 GLU B C   1 
ATOM   6095  O O   . GLU B 1 231 ? 88.473  132.812 88.389  1.00 66.58  ? 231 GLU B O   1 
ATOM   6096  C CB  . GLU B 1 231 ? 90.927  133.877 89.708  1.00 58.53  ? 231 GLU B CB  1 
ATOM   6097  C CG  . GLU B 1 231 ? 91.575  134.966 90.572  1.00 60.62  ? 231 GLU B CG  1 
ATOM   6098  C CD  . GLU B 1 231 ? 92.611  135.779 89.792  1.00 61.83  ? 231 GLU B CD  1 
ATOM   6099  O OE1 . GLU B 1 231 ? 93.496  135.187 89.136  1.00 62.92  ? 231 GLU B OE1 1 
ATOM   6100  O OE2 . GLU B 1 231 ? 92.546  137.028 89.836  1.00 63.22  ? 231 GLU B OE2 1 
ATOM   6101  N N   . ASN B 1 232 ? 88.863  131.006 89.650  1.00 57.16  ? 232 ASN B N   1 
ATOM   6102  C CA  . ASN B 1 232 ? 88.161  130.097 88.738  1.00 59.33  ? 232 ASN B CA  1 
ATOM   6103  C C   . ASN B 1 232 ? 86.646  130.407 88.627  1.00 60.58  ? 232 ASN B C   1 
ATOM   6104  O O   . ASN B 1 232 ? 86.051  130.928 89.574  1.00 60.33  ? 232 ASN B O   1 
ATOM   6105  C CB  . ASN B 1 232 ? 88.408  128.631 89.137  1.00 58.36  ? 232 ASN B CB  1 
ATOM   6106  C CG  . ASN B 1 232 ? 87.540  128.169 90.289  1.00 59.93  ? 232 ASN B CG  1 
ATOM   6107  O OD1 . ASN B 1 232 ? 86.418  127.733 90.096  1.00 60.95  ? 232 ASN B OD1 1 
ATOM   6108  N ND2 . ASN B 1 232 ? 88.015  128.259 91.502  1.00 54.49  ? 232 ASN B ND2 1 
ATOM   6109  N N   . PRO B 1 233 ? 85.992  130.063 87.501  1.00 62.00  ? 233 PRO B N   1 
ATOM   6110  C CA  . PRO B 1 233 ? 84.570  130.333 87.292  1.00 61.49  ? 233 PRO B CA  1 
ATOM   6111  C C   . PRO B 1 233 ? 83.617  129.297 87.921  1.00 63.66  ? 233 PRO B C   1 
ATOM   6112  O O   . PRO B 1 233 ? 82.434  129.586 88.085  1.00 63.41  ? 233 PRO B O   1 
ATOM   6113  C CB  . PRO B 1 233 ? 84.413  130.361 85.774  1.00 60.40  ? 233 PRO B CB  1 
ATOM   6114  C CG  . PRO B 1 233 ? 85.445  129.346 85.294  1.00 61.39  ? 233 PRO B CG  1 
ATOM   6115  C CD  . PRO B 1 233 ? 86.592  129.547 86.279  1.00 59.44  ? 233 PRO B CD  1 
ATOM   6116  N N   . HIS B 1 234 ? 84.081  128.087 88.236  1.00 64.62  ? 234 HIS B N   1 
ATOM   6117  C CA  . HIS B 1 234 ? 83.234  126.949 88.632  1.00 64.80  ? 234 HIS B CA  1 
ATOM   6118  C C   . HIS B 1 234 ? 82.736  127.071 90.073  1.00 63.52  ? 234 HIS B C   1 
ATOM   6119  O O   . HIS B 1 234 ? 81.516  126.954 90.292  1.00 63.23  ? 234 HIS B O   1 
ATOM   6120  C CB  . HIS B 1 234 ? 84.007  125.637 88.435  1.00 63.55  ? 234 HIS B CB  1 
ATOM   6121  C CG  . HIS B 1 234 ? 85.198  125.777 87.548  1.00 65.40  ? 234 HIS B CG  1 
ATOM   6122  N ND1 . HIS B 1 234 ? 85.088  125.884 86.176  1.00 65.39  ? 234 HIS B ND1 1 
ATOM   6123  C CD2 . HIS B 1 234 ? 86.518  125.829 87.827  1.00 65.37  ? 234 HIS B CD2 1 
ATOM   6124  C CE1 . HIS B 1 234 ? 86.290  125.994 85.648  1.00 65.63  ? 234 HIS B CE1 1 
ATOM   6125  N NE2 . HIS B 1 234 ? 87.185  125.966 86.641  1.00 65.51  ? 234 HIS B NE2 1 
ATOM   6126  N N   . GLN B 1 235 ? 83.659  127.308 91.002  1.00 64.12  ? 235 GLN B N   1 
ATOM   6127  C CA  . GLN B 1 235 ? 83.377  127.715 92.375  1.00 62.88  ? 235 GLN B CA  1 
ATOM   6128  C C   . GLN B 1 235 ? 84.602  128.460 92.923  1.00 63.19  ? 235 GLN B C   1 
ATOM   6129  O O   . GLN B 1 235 ? 85.624  127.824 93.200  1.00 60.94  ? 235 GLN B O   1 
ATOM   6130  C CB  . GLN B 1 235 ? 83.009  126.507 93.256  1.00 59.15  ? 235 GLN B CB  1 
ATOM   6131  C CG  . GLN B 1 235 ? 82.689  126.957 94.690  1.00 61.24  ? 235 GLN B CG  1 
ATOM   6132  C CD  . GLN B 1 235 ? 82.245  125.828 95.615  1.00 64.73  ? 235 GLN B CD  1 
ATOM   6133  O OE1 . GLN B 1 235 ? 81.622  124.857 95.219  1.00 64.60  ? 235 GLN B OE1 1 
ATOM   6134  N NE2 . GLN B 1 235 ? 82.553  125.927 96.891  1.00 64.37  ? 235 GLN B NE2 1 
ATOM   6135  N N   . PRO B 1 236 ? 84.536  129.788 93.109  1.00 64.19  ? 236 PRO B N   1 
ATOM   6136  C CA  . PRO B 1 236 ? 85.622  130.533 93.725  1.00 58.92  ? 236 PRO B CA  1 
ATOM   6137  C C   . PRO B 1 236 ? 85.649  130.323 95.244  1.00 57.63  ? 236 PRO B C   1 
ATOM   6138  O O   . PRO B 1 236 ? 84.612  130.330 95.910  1.00 57.68  ? 236 PRO B O   1 
ATOM   6139  C CB  . PRO B 1 236 ? 85.370  131.988 93.333  1.00 57.66  ? 236 PRO B CB  1 
ATOM   6140  C CG  . PRO B 1 236 ? 83.851  132.063 93.214  1.00 59.47  ? 236 PRO B CG  1 
ATOM   6141  C CD  . PRO B 1 236 ? 83.465  130.681 92.697  1.00 58.85  ? 236 PRO B CD  1 
ATOM   6142  N N   . ALA B 1 237 ? 86.840  130.184 95.813  1.00 53.18  ? 237 ALA B N   1 
ATOM   6143  C CA  . ALA B 1 237 ? 87.083  130.337 97.238  1.00 52.62  ? 237 ALA B CA  1 
ATOM   6144  C C   . ALA B 1 237 ? 86.848  131.797 97.663  1.00 54.60  ? 237 ALA B C   1 
ATOM   6145  O O   . ALA B 1 237 ? 87.100  132.726 96.894  1.00 56.16  ? 237 ALA B O   1 
ATOM   6146  C CB  . ALA B 1 237 ? 88.513  129.908 97.558  1.00 51.41  ? 237 ALA B CB  1 
ATOM   6147  N N   . SER B 1 238 ? 86.407  132.013 98.899  1.00 44.30  ? 238 SER B N   1 
ATOM   6148  C CA  . SER B 1 238 ? 86.321  133.343 99.492  1.00 46.74  ? 238 SER B CA  1 
ATOM   6149  C C   . SER B 1 238 ? 87.402  133.507 100.555 1.00 46.04  ? 238 SER B C   1 
ATOM   6150  O O   . SER B 1 238 ? 87.602  132.643 101.405 1.00 49.21  ? 238 SER B O   1 
ATOM   6151  C CB  . SER B 1 238 ? 84.912  133.650 100.004 1.00 48.04  ? 238 SER B CB  1 
ATOM   6152  O OG  . SER B 1 238 ? 84.488  132.749 100.999 1.00 48.60  ? 238 SER B OG  1 
ATOM   6153  N N   . LEU B 1 239 ? 88.090  134.648 100.526 1.00 42.88  ? 239 LEU B N   1 
ATOM   6154  C CA  . LEU B 1 239 ? 89.074  135.023 101.546 1.00 42.11  ? 239 LEU B CA  1 
ATOM   6155  C C   . LEU B 1 239 ? 88.415  135.213 102.922 1.00 43.31  ? 239 LEU B C   1 
ATOM   6156  O O   . LEU B 1 239 ? 89.069  135.089 103.952 1.00 44.60  ? 239 LEU B O   1 
ATOM   6157  C CB  . LEU B 1 239 ? 89.789  136.303 101.081 1.00 38.98  ? 239 LEU B CB  1 
ATOM   6158  C CG  . LEU B 1 239 ? 90.664  136.074 99.839  1.00 42.76  ? 239 LEU B CG  1 
ATOM   6159  C CD1 . LEU B 1 239 ? 90.942  137.363 99.095  1.00 43.81  ? 239 LEU B CD1 1 
ATOM   6160  C CD2 . LEU B 1 239 ? 91.999  135.461 100.218 1.00 41.72  ? 239 LEU B CD2 1 
ATOM   6161  N N   . GLU B 1 240 ? 87.108  135.466 102.933 1.00 44.40  ? 240 GLU B N   1 
ATOM   6162  C CA  . GLU B 1 240 ? 86.262  135.594 104.116 1.00 42.92  ? 240 GLU B CA  1 
ATOM   6163  C C   . GLU B 1 240 ? 85.950  134.269 104.818 1.00 44.65  ? 240 GLU B C   1 
ATOM   6164  O O   . GLU B 1 240 ? 85.472  134.296 105.948 1.00 50.87  ? 240 GLU B O   1 
ATOM   6165  C CB  . GLU B 1 240 ? 84.910  136.193 103.711 1.00 45.86  ? 240 GLU B CB  1 
ATOM   6166  C CG  . GLU B 1 240 ? 84.979  137.528 102.975 1.00 46.07  ? 240 GLU B CG  1 
ATOM   6167  C CD  . GLU B 1 240 ? 83.559  138.044 102.716 1.00 52.24  ? 240 GLU B CD  1 
ATOM   6168  O OE1 . GLU B 1 240 ? 82.842  138.367 103.687 1.00 50.19  ? 240 GLU B OE1 1 
ATOM   6169  O OE2 . GLU B 1 240 ? 83.139  138.084 101.538 1.00 54.52  ? 240 GLU B OE2 1 
ATOM   6170  N N   . ALA B 1 241 ? 86.135  133.118 104.169 1.00 42.09  ? 241 ALA B N   1 
ATOM   6171  C CA  . ALA B 1 241 ? 85.724  131.829 104.722 1.00 39.61  ? 241 ALA B CA  1 
ATOM   6172  C C   . ALA B 1 241 ? 86.527  131.454 105.977 1.00 36.97  ? 241 ALA B C   1 
ATOM   6173  O O   . ALA B 1 241 ? 87.741  131.645 106.036 1.00 39.55  ? 241 ALA B O   1 
ATOM   6174  C CB  . ALA B 1 241 ? 85.832  130.753 103.643 1.00 41.33  ? 241 ALA B CB  1 
ATOM   6175  N N   . THR B 1 242 ? 85.850  130.887 106.974 1.00 37.09  ? 242 THR B N   1 
ATOM   6176  C CA  . THR B 1 242 ? 86.419  130.589 108.298 1.00 38.69  ? 242 THR B CA  1 
ATOM   6177  C C   . THR B 1 242 ? 86.341  129.113 108.676 1.00 36.50  ? 242 THR B C   1 
ATOM   6178  O O   . THR B 1 242 ? 85.434  128.385 108.266 1.00 41.05  ? 242 THR B O   1 
ATOM   6179  C CB  . THR B 1 242 ? 85.785  131.437 109.409 1.00 39.06  ? 242 THR B CB  1 
ATOM   6180  O OG1 . THR B 1 242 ? 84.393  131.254 109.452 1.00 44.88  ? 242 THR B OG1 1 
ATOM   6181  C CG2 . THR B 1 242 ? 86.066  132.924 109.257 1.00 34.83  ? 242 THR B CG2 1 
ATOM   6182  N N   . ASP B 1 243 ? 87.318  128.662 109.463 1.00 34.90  ? 243 ASP B N   1 
ATOM   6183  C CA  . ASP B 1 243 ? 87.303  127.263 109.979 1.00 31.94  ? 243 ASP B CA  1 
ATOM   6184  C C   . ASP B 1 243 ? 86.575  127.145 111.332 1.00 37.80  ? 243 ASP B C   1 
ATOM   6185  O O   . ASP B 1 243 ? 85.929  128.130 111.740 1.00 46.01  ? 243 ASP B O   1 
ATOM   6186  C CB  . ASP B 1 243 ? 88.726  126.712 110.102 1.00 33.87  ? 243 ASP B CB  1 
ATOM   6187  C CG  . ASP B 1 243 ? 89.532  127.365 111.212 1.00 38.18  ? 243 ASP B CG  1 
ATOM   6188  O OD1 . ASP B 1 243 ? 88.969  128.233 111.909 1.00 42.62  ? 243 ASP B OD1 1 
ATOM   6189  O OD2 . ASP B 1 243 ? 90.712  126.998 111.371 1.00 42.72  ? 243 ASP B OD2 1 
ATOM   6190  N N   . SER B 1 244 ? 86.683  125.990 111.994 1.00 40.28  ? 244 SER B N   1 
ATOM   6191  C CA  . SER B 1 244 ? 85.991  125.694 113.258 1.00 40.03  ? 244 SER B CA  1 
ATOM   6192  C C   . SER B 1 244 ? 86.424  126.546 114.463 1.00 42.75  ? 244 SER B C   1 
ATOM   6193  O O   . SER B 1 244 ? 85.729  126.542 115.475 1.00 47.88  ? 244 SER B O   1 
ATOM   6194  C CB  . SER B 1 244 ? 86.173  124.220 113.622 1.00 44.79  ? 244 SER B CB  1 
ATOM   6195  O OG  . SER B 1 244 ? 85.794  123.377 112.553 1.00 49.99  ? 244 SER B OG  1 
ATOM   6196  N N   . LEU B 1 245 ? 87.544  127.270 114.384 1.00 43.98  ? 245 LEU B N   1 
ATOM   6197  C CA  . LEU B 1 245 ? 87.986  128.282 115.358 1.00 35.77  ? 245 LEU B CA  1 
ATOM   6198  C C   . LEU B 1 245 ? 87.574  129.704 114.946 1.00 36.71  ? 245 LEU B C   1 
ATOM   6199  O O   . LEU B 1 245 ? 87.877  130.665 115.650 1.00 38.00  ? 245 LEU B O   1 
ATOM   6200  C CB  . LEU B 1 245 ? 89.514  128.221 115.527 1.00 37.06  ? 245 LEU B CB  1 
ATOM   6201  C CG  . LEU B 1 245 ? 90.075  126.912 116.094 1.00 39.58  ? 245 LEU B CG  1 
ATOM   6202  C CD1 . LEU B 1 245 ? 91.599  126.959 116.077 1.00 40.08  ? 245 LEU B CD1 1 
ATOM   6203  C CD2 . LEU B 1 245 ? 89.628  126.681 117.534 1.00 36.18  ? 245 LEU B CD2 1 
ATOM   6204  N N   . GLY B 1 246 ? 86.921  129.867 113.795 1.00 33.08  ? 246 GLY B N   1 
ATOM   6205  C CA  . GLY B 1 246 ? 86.619  131.152 113.181 1.00 25.62  ? 246 GLY B CA  1 
ATOM   6206  C C   . GLY B 1 246 ? 87.807  131.782 112.449 1.00 34.06  ? 246 GLY B C   1 
ATOM   6207  O O   . GLY B 1 246 ? 87.728  132.941 112.067 1.00 39.09  ? 246 GLY B O   1 
ATOM   6208  N N   . ASN B 1 247 ? 88.915  131.069 112.260 1.00 33.88  ? 247 ASN B N   1 
ATOM   6209  C CA  . ASN B 1 247 ? 90.097  131.595 111.589 1.00 25.19  ? 247 ASN B CA  1 
ATOM   6210  C C   . ASN B 1 247 ? 89.897  131.668 110.070 1.00 29.26  ? 247 ASN B C   1 
ATOM   6211  O O   . ASN B 1 247 ? 89.518  130.683 109.443 1.00 38.12  ? 247 ASN B O   1 
ATOM   6212  C CB  . ASN B 1 247 ? 91.315  130.735 111.967 1.00 24.05  ? 247 ASN B CB  1 
ATOM   6213  C CG  . ASN B 1 247 ? 91.799  130.951 113.383 1.00 26.15  ? 247 ASN B CG  1 
ATOM   6214  O OD1 . ASN B 1 247 ? 91.474  131.916 114.044 1.00 27.63  ? 247 ASN B OD1 1 
ATOM   6215  N ND2 . ASN B 1 247 ? 92.637  130.093 113.891 1.00 31.94  ? 247 ASN B ND2 1 
ATOM   6216  N N   . THR B 1 248 ? 90.183  132.824 109.475 1.00 30.79  ? 248 THR B N   1 
ATOM   6217  C CA  . THR B 1 248 ? 90.351  132.988 108.022 1.00 27.78  ? 248 THR B CA  1 
ATOM   6218  C C   . THR B 1 248 ? 91.717  132.468 107.567 1.00 20.28  ? 248 THR B C   1 
ATOM   6219  O O   . THR B 1 248 ? 92.558  132.094 108.380 1.00 33.21  ? 248 THR B O   1 
ATOM   6220  C CB  . THR B 1 248 ? 90.206  134.457 107.593 1.00 30.34  ? 248 THR B CB  1 
ATOM   6221  O OG1 . THR B 1 248 ? 91.286  135.234 108.066 1.00 34.73  ? 248 THR B OG1 1 
ATOM   6222  C CG2 . THR B 1 248 ? 88.901  135.107 108.031 1.00 27.88  ? 248 THR B CG2 1 
ATOM   6223  N N   . VAL B 1 249 ? 92.001  132.495 106.266 1.00 20.48  ? 249 VAL B N   1 
ATOM   6224  C CA  . VAL B 1 249 ? 93.348  132.201 105.752 1.00 24.97  ? 249 VAL B CA  1 
ATOM   6225  C C   . VAL B 1 249 ? 94.429  133.141 106.313 1.00 21.26  ? 249 VAL B C   1 
ATOM   6226  O O   . VAL B 1 249 ? 95.559  132.713 106.521 1.00 22.01  ? 249 VAL B O   1 
ATOM   6227  C CB  . VAL B 1 249 ? 93.332  132.172 104.214 1.00 25.94  ? 249 VAL B CB  1 
ATOM   6228  C CG1 . VAL B 1 249 ? 92.915  133.499 103.579 1.00 21.65  ? 249 VAL B CG1 1 
ATOM   6229  C CG2 . VAL B 1 249 ? 94.689  131.760 103.655 1.00 24.17  ? 249 VAL B CG2 1 
ATOM   6230  N N   . LEU B 1 250 ? 94.107  134.396 106.645 1.00 29.96  ? 250 LEU B N   1 
ATOM   6231  C CA  . LEU B 1 250 ? 95.063  135.329 107.252 1.00 23.13  ? 250 LEU B CA  1 
ATOM   6232  C C   . LEU B 1 250 ? 95.354  134.994 108.716 1.00 24.29  ? 250 LEU B C   1 
ATOM   6233  O O   . LEU B 1 250 ? 96.497  135.097 109.152 1.00 27.98  ? 250 LEU B O   1 
ATOM   6234  C CB  . LEU B 1 250 ? 94.559  136.773 107.122 1.00 21.02  ? 250 LEU B CB  1 
ATOM   6235  C CG  . LEU B 1 250 ? 94.406  137.297 105.688 1.00 25.33  ? 250 LEU B CG  1 
ATOM   6236  C CD1 . LEU B 1 250 ? 93.957  138.755 105.749 1.00 30.18  ? 250 LEU B CD1 1 
ATOM   6237  C CD2 . LEU B 1 250 ? 95.697  137.238 104.876 1.00 20.23  ? 250 LEU B CD2 1 
ATOM   6238  N N   . HIS B 1 251 ? 94.361  134.524 109.469 1.00 27.71  ? 251 HIS B N   1 
ATOM   6239  C CA  . HIS B 1 251 ? 94.579  133.954 110.799 1.00 15.90  ? 251 HIS B CA  1 
ATOM   6240  C C   . HIS B 1 251 ? 95.392  132.661 110.739 1.00 23.68  ? 251 HIS B C   1 
ATOM   6241  O O   . HIS B 1 251 ? 96.307  132.512 111.572 1.00 31.90  ? 251 HIS B O   1 
ATOM   6242  C CB  . HIS B 1 251 ? 93.233  133.684 111.488 1.00 19.81  ? 251 HIS B CB  1 
ATOM   6243  C CG  . HIS B 1 251 ? 92.432  134.907 111.789 1.00 18.53  ? 251 HIS B CG  1 
ATOM   6244  N ND1 . HIS B 1 251 ? 91.444  135.368 110.940 1.00 20.49  ? 251 HIS B ND1 1 
ATOM   6245  C CD2 . HIS B 1 251 ? 92.457  135.754 112.841 1.00 23.02  ? 251 HIS B CD2 1 
ATOM   6246  C CE1 . HIS B 1 251 ? 90.899  136.452 111.454 1.00 27.82  ? 251 HIS B CE1 1 
ATOM   6247  N NE2 . HIS B 1 251 ? 91.503  136.708 112.621 1.00 34.92  ? 251 HIS B NE2 1 
ATOM   6248  N N   . ALA B 1 252 ? 95.089  131.768 109.796 1.00 28.18  ? 252 ALA B N   1 
ATOM   6249  C CA  . ALA B 1 252 ? 95.838  130.539 109.578 1.00 11.95  ? 252 ALA B CA  1 
ATOM   6250  C C   . ALA B 1 252 ? 97.314  130.805 109.242 1.00 15.52  ? 252 ALA B C   1 
ATOM   6251  O O   . ALA B 1 252 ? 98.183  130.134 109.781 1.00 26.86  ? 252 ALA B O   1 
ATOM   6252  C CB  . ALA B 1 252 ? 95.144  129.727 108.488 1.00 18.76  ? 252 ALA B CB  1 
ATOM   6253  N N   . LEU B 1 253 ? 97.632  131.813 108.439 1.00 23.12  ? 253 LEU B N   1 
ATOM   6254  C CA  . LEU B 1 253 ? 99.015  132.207 108.173 1.00 20.48  ? 253 LEU B CA  1 
ATOM   6255  C C   . LEU B 1 253 ? 99.760  132.678 109.425 1.00 25.50  ? 253 LEU B C   1 
ATOM   6256  O O   . LEU B 1 253 ? 100.901 132.292 109.643 1.00 35.87  ? 253 LEU B O   1 
ATOM   6257  C CB  . LEU B 1 253 ? 99.011  133.289 107.089 1.00 22.31  ? 253 LEU B CB  1 
ATOM   6258  C CG  . LEU B 1 253 ? 98.931  132.684 105.685 1.00 27.24  ? 253 LEU B CG  1 
ATOM   6259  C CD1 . LEU B 1 253 ? 98.497  133.744 104.696 1.00 29.89  ? 253 LEU B CD1 1 
ATOM   6260  C CD2 . LEU B 1 253 ? 100.297 132.178 105.239 1.00 28.53  ? 253 LEU B CD2 1 
ATOM   6261  N N   . VAL B 1 254 ? 99.111  133.454 110.291 1.00 23.38  ? 254 VAL B N   1 
ATOM   6262  C CA  . VAL B 1 254 ? 99.654  133.803 111.609 1.00 19.83  ? 254 VAL B CA  1 
ATOM   6263  C C   . VAL B 1 254 ? 99.867  132.553 112.475 1.00 26.60  ? 254 VAL B C   1 
ATOM   6264  O O   . VAL B 1 254 ? 100.889 132.429 113.147 1.00 33.89  ? 254 VAL B O   1 
ATOM   6265  C CB  . VAL B 1 254 ? 98.746  134.848 112.283 1.00 23.87  ? 254 VAL B CB  1 
ATOM   6266  C CG1 . VAL B 1 254 ? 99.103  135.081 113.744 1.00 21.26  ? 254 VAL B CG1 1 
ATOM   6267  C CG2 . VAL B 1 254 ? 98.854  136.192 111.557 1.00 16.74  ? 254 VAL B CG2 1 
ATOM   6268  N N   . MET B 1 255 ? 98.962  131.578 112.433 1.00 22.15  ? 255 MET B N   1 
ATOM   6269  C CA  . MET B 1 255 ? 99.110  130.307 113.139 1.00 14.53  ? 255 MET B CA  1 
ATOM   6270  C C   . MET B 1 255 ? 100.255 129.423 112.619 1.00 23.85  ? 255 MET B C   1 
ATOM   6271  O O   . MET B 1 255 ? 100.897 128.788 113.447 1.00 31.57  ? 255 MET B O   1 
ATOM   6272  C CB  . MET B 1 255 ? 97.792  129.533 113.131 1.00 24.33  ? 255 MET B CB  1 
ATOM   6273  C CG  . MET B 1 255 ? 96.704  130.180 113.986 1.00 22.89  ? 255 MET B CG  1 
ATOM   6274  S SD  . MET B 1 255 ? 97.086  130.252 115.755 1.00 45.65  ? 255 MET B SD  1 
ATOM   6275  C CE  . MET B 1 255 ? 95.412  130.144 116.437 1.00 29.01  ? 255 MET B CE  1 
ATOM   6276  N N   . ILE B 1 256 ? 100.591 129.416 111.321 1.00 27.68  ? 256 ILE B N   1 
ATOM   6277  C CA  . ILE B 1 256 ? 101.773 128.642 110.820 1.00 25.01  ? 256 ILE B CA  1 
ATOM   6278  C C   . ILE B 1 256 ? 103.114 129.376 111.044 1.00 30.62  ? 256 ILE B C   1 
ATOM   6279  O O   . ILE B 1 256 ? 104.148 128.754 110.734 1.00 41.06  ? 256 ILE B O   1 
ATOM   6280  C CB  . ILE B 1 256 ? 101.583 128.288 109.330 1.00 27.54  ? 256 ILE B CB  1 
ATOM   6281  C CG1 . ILE B 1 256 ? 101.623 129.534 108.443 1.00 27.38  ? 256 ILE B CG1 1 
ATOM   6282  C CG2 . ILE B 1 256 ? 100.306 127.486 109.125 1.00 27.03  ? 256 ILE B CG2 1 
ATOM   6283  C CD1 . ILE B 1 256 ? 101.537 129.237 106.965 1.00 27.01  ? 256 ILE B CD1 1 
ATOM   6284  N N   . ALA B 1 257 ? 103.135 130.621 111.545 1.00 28.72  ? 257 ALA B N   1 
ATOM   6285  C CA  . ALA B 1 257 ? 104.383 131.343 111.695 1.00 25.99  ? 257 ALA B CA  1 
ATOM   6286  C C   . ALA B 1 257 ? 105.237 130.845 112.869 1.00 34.53  ? 257 ALA B C   1 
ATOM   6287  O O   . ALA B 1 257 ? 104.776 130.784 114.009 1.00 37.47  ? 257 ALA B O   1 
ATOM   6288  C CB  . ALA B 1 257 ? 104.059 132.835 111.812 1.00 24.71  ? 257 ALA B CB  1 
ATOM   6289  N N   . ASP B 1 258 ? 106.490 130.511 112.603 1.00 43.05  ? 258 ASP B N   1 
ATOM   6290  C CA  . ASP B 1 258 ? 107.603 130.481 113.575 1.00 43.07  ? 258 ASP B CA  1 
ATOM   6291  C C   . ASP B 1 258 ? 108.420 131.792 113.290 1.00 48.74  ? 258 ASP B C   1 
ATOM   6292  O O   . ASP B 1 258 ? 108.134 132.459 112.276 1.00 49.14  ? 258 ASP B O   1 
ATOM   6293  C CB  . ASP B 1 258 ? 108.441 129.208 113.450 1.00 47.09  ? 258 ASP B CB  1 
ATOM   6294  C CG  . ASP B 1 258 ? 109.395 129.230 112.268 1.00 51.53  ? 258 ASP B CG  1 
ATOM   6295  O OD1 . ASP B 1 258 ? 109.715 130.337 111.796 1.00 53.99  ? 258 ASP B OD1 1 
ATOM   6296  O OD2 . ASP B 1 258 ? 109.810 128.138 111.831 1.00 47.82  ? 258 ASP B OD2 1 
ATOM   6297  N N   . ASN B 1 259 ? 109.363 132.118 114.166 1.00 44.34  ? 259 ASN B N   1 
ATOM   6298  C CA  . ASN B 1 259 ? 110.100 133.378 114.064 1.00 45.47  ? 259 ASN B CA  1 
ATOM   6299  C C   . ASN B 1 259 ? 111.449 133.237 113.334 1.00 51.16  ? 259 ASN B C   1 
ATOM   6300  O O   . ASN B 1 259 ? 112.282 134.139 113.395 1.00 53.07  ? 259 ASN B O   1 
ATOM   6301  C CB  . ASN B 1 259 ? 110.134 134.030 115.454 1.00 47.98  ? 259 ASN B CB  1 
ATOM   6302  C CG  . ASN B 1 259 ? 108.727 134.269 115.976 1.00 42.84  ? 259 ASN B CG  1 
ATOM   6303  O OD1 . ASN B 1 259 ? 107.958 135.039 115.430 1.00 42.71  ? 259 ASN B OD1 1 
ATOM   6304  N ND2 . ASN B 1 259 ? 108.326 133.599 117.029 1.00 43.99  ? 259 ASN B ND2 1 
ATOM   6305  N N   . SER B 1 260 ? 111.681 132.123 112.628 1.00 53.19  ? 260 SER B N   1 
ATOM   6306  C CA  . SER B 1 260 ? 112.833 131.953 111.732 1.00 52.24  ? 260 SER B CA  1 
ATOM   6307  C C   . SER B 1 260 ? 112.681 132.820 110.469 1.00 52.92  ? 260 SER B C   1 
ATOM   6308  O O   . SER B 1 260 ? 111.553 133.100 110.047 1.00 51.49  ? 260 SER B O   1 
ATOM   6309  C CB  . SER B 1 260 ? 113.021 130.480 111.364 1.00 55.32  ? 260 SER B CB  1 
ATOM   6310  O OG  . SER B 1 260 ? 112.006 130.040 110.496 1.00 54.95  ? 260 SER B OG  1 
ATOM   6311  N N   . PRO B 1 261 ? 113.780 133.281 109.846 1.00 58.49  ? 261 PRO B N   1 
ATOM   6312  C CA  . PRO B 1 261 ? 113.706 134.287 108.786 1.00 56.57  ? 261 PRO B CA  1 
ATOM   6313  C C   . PRO B 1 261 ? 113.084 133.764 107.488 1.00 54.33  ? 261 PRO B C   1 
ATOM   6314  O O   . PRO B 1 261 ? 112.342 134.494 106.834 1.00 54.56  ? 261 PRO B O   1 
ATOM   6315  C CB  . PRO B 1 261 ? 115.143 134.776 108.589 1.00 54.71  ? 261 PRO B CB  1 
ATOM   6316  C CG  . PRO B 1 261 ? 116.001 133.628 109.108 1.00 54.24  ? 261 PRO B CG  1 
ATOM   6317  C CD  . PRO B 1 261 ? 115.160 133.051 110.237 1.00 52.77  ? 261 PRO B CD  1 
ATOM   6318  N N   . GLU B 1 262 ? 113.317 132.500 107.129 1.00 55.90  ? 262 GLU B N   1 
ATOM   6319  C CA  . GLU B 1 262 ? 112.720 131.884 105.940 1.00 57.87  ? 262 GLU B CA  1 
ATOM   6320  C C   . GLU B 1 262 ? 111.212 131.673 106.113 1.00 58.14  ? 262 GLU B C   1 
ATOM   6321  O O   . GLU B 1 262 ? 110.431 132.131 105.286 1.00 61.30  ? 262 GLU B O   1 
ATOM   6322  C CB  . GLU B 1 262 ? 113.456 130.586 105.573 1.00 58.17  ? 262 GLU B CB  1 
ATOM   6323  C CG  . GLU B 1 262 ? 112.870 129.932 104.311 1.00 61.81  ? 262 GLU B CG  1 
ATOM   6324  C CD  . GLU B 1 262 ? 113.785 128.883 103.664 1.00 64.93  ? 262 GLU B CD  1 
ATOM   6325  O OE1 . GLU B 1 262 ? 114.666 128.317 104.347 1.00 61.46  ? 262 GLU B OE1 1 
ATOM   6326  O OE2 . GLU B 1 262 ? 113.616 128.611 102.452 1.00 63.73  ? 262 GLU B OE2 1 
ATOM   6327  N N   . ASN B 1 263 ? 110.772 131.066 107.215 1.00 49.25  ? 263 ASN B N   1 
ATOM   6328  C CA  . ASN B 1 263 ? 109.342 130.915 107.483 1.00 46.54  ? 263 ASN B CA  1 
ATOM   6329  C C   . ASN B 1 263 ? 108.625 132.273 107.548 1.00 47.73  ? 263 ASN B C   1 
ATOM   6330  O O   . ASN B 1 263 ? 107.534 132.420 107.002 1.00 47.51  ? 263 ASN B O   1 
ATOM   6331  C CB  . ASN B 1 263 ? 109.153 130.141 108.787 1.00 45.76  ? 263 ASN B CB  1 
ATOM   6332  C CG  . ASN B 1 263 ? 107.686 129.989 109.111 1.00 46.36  ? 263 ASN B CG  1 
ATOM   6333  O OD1 . ASN B 1 263 ? 107.102 130.778 109.829 1.00 48.67  ? 263 ASN B OD1 1 
ATOM   6334  N ND2 . ASN B 1 263 ? 107.020 129.008 108.571 1.00 47.46  ? 263 ASN B ND2 1 
ATOM   6335  N N   . SER B 1 264 ? 109.259 133.284 108.142 1.00 47.72  ? 264 SER B N   1 
ATOM   6336  C CA  . SER B 1 264 ? 108.708 134.634 108.199 1.00 42.28  ? 264 SER B CA  1 
ATOM   6337  C C   . SER B 1 264 ? 108.550 135.233 106.807 1.00 41.62  ? 264 SER B C   1 
ATOM   6338  O O   . SER B 1 264 ? 107.462 135.688 106.475 1.00 42.97  ? 264 SER B O   1 
ATOM   6339  C CB  . SER B 1 264 ? 109.572 135.545 109.064 1.00 46.36  ? 264 SER B CB  1 
ATOM   6340  O OG  . SER B 1 264 ? 109.671 135.019 110.364 1.00 46.80  ? 264 SER B OG  1 
ATOM   6341  N N   . ALA B 1 265 ? 109.579 135.192 105.958 1.00 49.65  ? 265 ALA B N   1 
ATOM   6342  C CA  . ALA B 1 265 ? 109.501 135.710 104.593 1.00 49.28  ? 265 ALA B CA  1 
ATOM   6343  C C   . ALA B 1 265 ? 108.378 135.051 103.780 1.00 45.20  ? 265 ALA B C   1 
ATOM   6344  O O   . ALA B 1 265 ? 107.656 135.730 103.056 1.00 49.34  ? 265 ALA B O   1 
ATOM   6345  C CB  . ALA B 1 265 ? 110.860 135.507 103.920 1.00 46.66  ? 265 ALA B CB  1 
ATOM   6346  N N   . LEU B 1 266 ? 108.184 133.741 103.940 1.00 39.15  ? 266 LEU B N   1 
ATOM   6347  C CA  . LEU B 1 266 ? 107.142 132.987 103.249 1.00 43.73  ? 266 LEU B CA  1 
ATOM   6348  C C   . LEU B 1 266 ? 105.731 133.282 103.771 1.00 42.38  ? 266 LEU B C   1 
ATOM   6349  O O   . LEU B 1 266 ? 104.827 133.505 102.967 1.00 44.06  ? 266 LEU B O   1 
ATOM   6350  C CB  . LEU B 1 266 ? 107.496 131.492 103.304 1.00 48.84  ? 266 LEU B CB  1 
ATOM   6351  C CG  . LEU B 1 266 ? 108.822 131.159 102.591 1.00 49.43  ? 266 LEU B CG  1 
ATOM   6352  C CD1 . LEU B 1 266 ? 109.160 129.688 102.796 1.00 48.26  ? 266 LEU B CD1 1 
ATOM   6353  C CD2 . LEU B 1 266 ? 108.780 131.494 101.104 1.00 44.61  ? 266 LEU B CD2 1 
ATOM   6354  N N   . VAL B 1 267 ? 105.528 133.369 105.086 1.00 42.74  ? 267 VAL B N   1 
ATOM   6355  C CA  . VAL B 1 267 ? 104.246 133.811 105.664 1.00 38.93  ? 267 VAL B CA  1 
ATOM   6356  C C   . VAL B 1 267 ? 103.914 135.249 105.254 1.00 38.13  ? 267 VAL B C   1 
ATOM   6357  O O   . VAL B 1 267 ? 102.797 135.519 104.834 1.00 41.74  ? 267 VAL B O   1 
ATOM   6358  C CB  . VAL B 1 267 ? 104.237 133.642 107.195 1.00 38.99  ? 267 VAL B CB  1 
ATOM   6359  C CG1 . VAL B 1 267 ? 103.055 134.341 107.863 1.00 41.37  ? 267 VAL B CG1 1 
ATOM   6360  C CG2 . VAL B 1 267 ? 104.146 132.163 107.554 1.00 32.21  ? 267 VAL B CG2 1 
ATOM   6361  N N   . ILE B 1 268 ? 104.882 136.162 105.312 1.00 30.75  ? 268 ILE B N   1 
ATOM   6362  C CA  . ILE B 1 268 ? 104.727 137.569 104.935 1.00 35.51  ? 268 ILE B CA  1 
ATOM   6363  C C   . ILE B 1 268 ? 104.364 137.731 103.449 1.00 39.25  ? 268 ILE B C   1 
ATOM   6364  O O   . ILE B 1 268 ? 103.415 138.444 103.132 1.00 41.13  ? 268 ILE B O   1 
ATOM   6365  C CB  . ILE B 1 268 ? 105.998 138.347 105.345 1.00 35.82  ? 268 ILE B CB  1 
ATOM   6366  C CG1 . ILE B 1 268 ? 106.008 138.518 106.882 1.00 27.95  ? 268 ILE B CG1 1 
ATOM   6367  C CG2 . ILE B 1 268 ? 106.111 139.699 104.634 1.00 30.70  ? 268 ILE B CG2 1 
ATOM   6368  C CD1 . ILE B 1 268 ? 107.349 138.958 107.464 1.00 31.66  ? 268 ILE B CD1 1 
ATOM   6369  N N   . HIS B 1 269 ? 105.048 137.044 102.526 1.00 39.45  ? 269 HIS B N   1 
ATOM   6370  C CA  . HIS B 1 269 ? 104.707 137.110 101.100 1.00 41.19  ? 269 HIS B CA  1 
ATOM   6371  C C   . HIS B 1 269 ? 103.297 136.600 100.815 1.00 40.24  ? 269 HIS B C   1 
ATOM   6372  O O   . HIS B 1 269 ? 102.555 137.209 100.050 1.00 42.38  ? 269 HIS B O   1 
ATOM   6373  C CB  . HIS B 1 269 ? 105.722 136.330 100.248 1.00 45.24  ? 269 HIS B CB  1 
ATOM   6374  C CG  . HIS B 1 269 ? 107.018 137.060 100.007 1.00 49.32  ? 269 HIS B CG  1 
ATOM   6375  N ND1 . HIS B 1 269 ? 107.129 138.337 99.457  1.00 50.39  ? 269 HIS B ND1 1 
ATOM   6376  C CD2 . HIS B 1 269 ? 108.274 136.546 100.163 1.00 49.68  ? 269 HIS B CD2 1 
ATOM   6377  C CE1 . HIS B 1 269 ? 108.444 138.579 99.335  1.00 48.70  ? 269 HIS B CE1 1 
ATOM   6378  N NE2 . HIS B 1 269 ? 109.154 137.521 99.752  1.00 51.32  ? 269 HIS B NE2 1 
ATOM   6379  N N   . MET B 1 270 ? 102.903 135.495 101.442 1.00 37.54  ? 270 MET B N   1 
ATOM   6380  C CA  . MET B 1 270 ? 101.576 134.918 101.269 1.00 35.45  ? 270 MET B CA  1 
ATOM   6381  C C   . MET B 1 270 ? 100.480 135.813 101.857 1.00 34.54  ? 270 MET B C   1 
ATOM   6382  O O   . MET B 1 270 ? 99.462  136.050 101.211 1.00 35.64  ? 270 MET B O   1 
ATOM   6383  C CB  . MET B 1 270 ? 101.582 133.528 101.904 1.00 30.50  ? 270 MET B CB  1 
ATOM   6384  C CG  . MET B 1 270 ? 100.434 132.636 101.428 1.00 33.33  ? 270 MET B CG  1 
ATOM   6385  S SD  . MET B 1 270 ? 100.416 132.141 99.678  1.00 50.01  ? 270 MET B SD  1 
ATOM   6386  C CE  . MET B 1 270 ? 102.162 131.808 99.352  1.00 33.81  ? 270 MET B CE  1 
ATOM   6387  N N   . TYR B 1 271 ? 100.712 136.377 103.043 1.00 32.75  ? 271 TYR B N   1 
ATOM   6388  C CA  . TYR B 1 271 ? 99.807  137.302 103.719 1.00 24.68  ? 271 TYR B CA  1 
ATOM   6389  C C   . TYR B 1 271 ? 99.569  138.584 102.900 1.00 33.32  ? 271 TYR B C   1 
ATOM   6390  O O   . TYR B 1 271 ? 98.423  138.963 102.677 1.00 32.03  ? 271 TYR B O   1 
ATOM   6391  C CB  . TYR B 1 271 ? 100.385 137.589 105.115 1.00 29.68  ? 271 TYR B CB  1 
ATOM   6392  C CG  . TYR B 1 271 ? 99.446  138.307 106.057 1.00 28.78  ? 271 TYR B CG  1 
ATOM   6393  C CD1 . TYR B 1 271 ? 99.189  139.677 105.882 1.00 29.57  ? 271 TYR B CD1 1 
ATOM   6394  C CD2 . TYR B 1 271 ? 98.822  137.603 107.105 1.00 27.27  ? 271 TYR B CD2 1 
ATOM   6395  C CE1 . TYR B 1 271 ? 98.275  140.332 106.717 1.00 27.51  ? 271 TYR B CE1 1 
ATOM   6396  C CE2 . TYR B 1 271 ? 97.918  138.265 107.953 1.00 34.58  ? 271 TYR B CE2 1 
ATOM   6397  C CZ  . TYR B 1 271 ? 97.629  139.626 107.747 1.00 30.57  ? 271 TYR B CZ  1 
ATOM   6398  O OH  . TYR B 1 271 ? 96.752  140.273 108.544 1.00 31.93  ? 271 TYR B OH  1 
ATOM   6399  N N   . ASP B 1 272 ? 100.628 139.221 102.399 1.00 34.76  ? 272 ASP B N   1 
ATOM   6400  C CA  . ASP B 1 272 ? 100.513 140.399 101.536 1.00 31.24  ? 272 ASP B CA  1 
ATOM   6401  C C   . ASP B 1 272 ? 99.832  140.088 100.205 1.00 37.95  ? 272 ASP B C   1 
ATOM   6402  O O   . ASP B 1 272 ? 98.983  140.856 99.758  1.00 41.13  ? 272 ASP B O   1 
ATOM   6403  C CB  . ASP B 1 272 ? 101.896 140.994 101.255 1.00 39.06  ? 272 ASP B CB  1 
ATOM   6404  C CG  . ASP B 1 272 ? 102.521 141.747 102.430 1.00 44.94  ? 272 ASP B CG  1 
ATOM   6405  O OD1 . ASP B 1 272 ? 101.850 141.976 103.459 1.00 38.57  ? 272 ASP B OD1 1 
ATOM   6406  O OD2 . ASP B 1 272 ? 103.685 142.180 102.276 1.00 48.63  ? 272 ASP B OD2 1 
ATOM   6407  N N   . GLY B 1 273 ? 100.154 138.950 99.584  1.00 42.45  ? 273 GLY B N   1 
ATOM   6408  C CA  . GLY B 1 273 ? 99.508  138.488 98.367  1.00 31.66  ? 273 GLY B CA  1 
ATOM   6409  C C   . GLY B 1 273 ? 98.005  138.326 98.547  1.00 34.31  ? 273 GLY B C   1 
ATOM   6410  O O   . GLY B 1 273 ? 97.233  138.786 97.711  1.00 40.70  ? 273 GLY B O   1 
ATOM   6411  N N   . LEU B 1 274 ? 97.552  137.719 99.642  1.00 34.18  ? 274 LEU B N   1 
ATOM   6412  C CA  . LEU B 1 274 ? 96.127  137.531 99.901  1.00 35.65  ? 274 LEU B CA  1 
ATOM   6413  C C   . LEU B 1 274 ? 95.392  138.842 100.206 1.00 39.69  ? 274 LEU B C   1 
ATOM   6414  O O   . LEU B 1 274 ? 94.253  138.997 99.778  1.00 40.38  ? 274 LEU B O   1 
ATOM   6415  C CB  . LEU B 1 274 ? 95.951  136.525 101.036 1.00 33.09  ? 274 LEU B CB  1 
ATOM   6416  C CG  . LEU B 1 274 ? 96.367  135.098 100.660 1.00 34.17  ? 274 LEU B CG  1 
ATOM   6417  C CD1 . LEU B 1 274 ? 96.519  134.316 101.944 1.00 36.90  ? 274 LEU B CD1 1 
ATOM   6418  C CD2 . LEU B 1 274 ? 95.343  134.365 99.804  1.00 30.35  ? 274 LEU B CD2 1 
ATOM   6419  N N   . LEU B 1 275 ? 96.016  139.819 100.869 1.00 40.52  ? 275 LEU B N   1 
ATOM   6420  C CA  . LEU B 1 275 ? 95.433  141.159 100.985 1.00 37.48  ? 275 LEU B CA  1 
ATOM   6421  C C   . LEU B 1 275 ? 95.293  141.857 99.633  1.00 37.73  ? 275 LEU B C   1 
ATOM   6422  O O   . LEU B 1 275 ? 94.245  142.428 99.348  1.00 40.51  ? 275 LEU B O   1 
ATOM   6423  C CB  . LEU B 1 275 ? 96.281  142.047 101.898 1.00 39.89  ? 275 LEU B CB  1 
ATOM   6424  C CG  . LEU B 1 275 ? 96.186  141.740 103.390 1.00 36.61  ? 275 LEU B CG  1 
ATOM   6425  C CD1 . LEU B 1 275 ? 97.053  142.761 104.112 1.00 33.31  ? 275 LEU B CD1 1 
ATOM   6426  C CD2 . LEU B 1 275 ? 94.765  141.879 103.923 1.00 33.25  ? 275 LEU B CD2 1 
ATOM   6427  N N   . GLN B 1 276 ? 96.328  141.746 98.799  1.00 41.74  ? 276 GLN B N   1 
ATOM   6428  C CA  . GLN B 1 276 ? 96.272  142.334 97.431  1.00 38.63  ? 276 GLN B CA  1 
ATOM   6429  C C   . GLN B 1 276 ? 95.145  141.648 96.656  1.00 47.72  ? 276 GLN B C   1 
ATOM   6430  O O   . GLN B 1 276 ? 94.357  142.375 96.019  1.00 51.34  ? 276 GLN B O   1 
ATOM   6431  C CB  . GLN B 1 276 ? 97.629  142.199 96.740  1.00 41.81  ? 276 GLN B CB  1 
ATOM   6432  C CG  . GLN B 1 276 ? 98.723  143.007 97.422  1.00 42.18  ? 276 GLN B CG  1 
ATOM   6433  C CD  . GLN B 1 276 ? 99.907  143.257 96.522  1.00 49.93  ? 276 GLN B CD  1 
ATOM   6434  O OE1 . GLN B 1 276 ? 100.013 142.699 95.433  1.00 52.54  ? 276 GLN B OE1 1 
ATOM   6435  N NE2 . GLN B 1 276 ? 100.811 144.111 96.974  1.00 48.66  ? 276 GLN B NE2 1 
ATOM   6436  N N   . MET B 1 277 ? 95.052  140.313 96.704  1.00 49.97  ? 277 MET B N   1 
ATOM   6437  C CA  . MET B 1 277 ? 93.938  139.580 96.099  1.00 48.63  ? 277 MET B CA  1 
ATOM   6438  C C   . MET B 1 277 ? 92.582  140.045 96.631  1.00 46.20  ? 277 MET B C   1 
ATOM   6439  O O   . MET B 1 277 ? 91.677  140.294 95.841  1.00 51.66  ? 277 MET B O   1 
ATOM   6440  C CB  . MET B 1 277 ? 94.098  138.069 96.327  1.00 50.79  ? 277 MET B CB  1 
ATOM   6441  C CG  . MET B 1 277 ? 95.201  137.460 95.469  1.00 48.27  ? 277 MET B CG  1 
ATOM   6442  S SD  . MET B 1 277 ? 94.746  137.261 93.734  1.00 69.24  ? 277 MET B SD  1 
ATOM   6443  C CE  . MET B 1 277 ? 96.386  137.364 92.990  1.00 58.70  ? 277 MET B CE  1 
ATOM   6444  N N   . GLY B 1 278 ? 92.415  140.228 97.940  1.00 46.73  ? 278 GLY B N   1 
ATOM   6445  C CA  . GLY B 1 278 ? 91.177  140.737 98.527  1.00 47.91  ? 278 GLY B CA  1 
ATOM   6446  C C   . GLY B 1 278 ? 90.806  142.133 98.032  1.00 48.92  ? 278 GLY B C   1 
ATOM   6447  O O   . GLY B 1 278 ? 89.644  142.396 97.733  1.00 49.41  ? 278 GLY B O   1 
ATOM   6448  N N   . ALA B 1 279 ? 91.794  143.003 97.826  1.00 49.60  ? 279 ALA B N   1 
ATOM   6449  C CA  . ALA B 1 279 ? 91.615  144.319 97.227  1.00 48.29  ? 279 ALA B CA  1 
ATOM   6450  C C   . ALA B 1 279 ? 91.100  144.288 95.770  1.00 54.46  ? 279 ALA B C   1 
ATOM   6451  O O   . ALA B 1 279 ? 90.582  145.294 95.290  1.00 56.63  ? 279 ALA B O   1 
ATOM   6452  C CB  . ALA B 1 279 ? 92.946  145.063 97.344  1.00 46.44  ? 279 ALA B CB  1 
ATOM   6453  N N   . ARG B 1 280 ? 91.118  143.092 95.143  1.00 57.81  ? 280 ARG B N   1 
ATOM   6454  C CA  . ARG B 1 280 ? 90.631  142.905 93.739  1.00 52.49  ? 280 ARG B CA  1 
ATOM   6455  C C   . ARG B 1 280 ? 89.382  142.028 93.673  1.00 55.16  ? 280 ARG B C   1 
ATOM   6456  O O   . ARG B 1 280 ? 88.583  142.225 92.739  1.00 59.55  ? 280 ARG B O   1 
ATOM   6457  C CB  . ARG B 1 280 ? 91.637  142.122 92.884  1.00 54.75  ? 280 ARG B CB  1 
ATOM   6458  C CG  . ARG B 1 280 ? 92.939  142.891 92.610  1.00 56.41  ? 280 ARG B CG  1 
ATOM   6459  C CD  . ARG B 1 280 ? 94.013  141.995 91.987  1.00 58.94  ? 280 ARG B CD  1 
ATOM   6460  N NE  . ARG B 1 280 ? 93.519  141.321 90.795  1.00 61.25  ? 280 ARG B NE  1 
ATOM   6461  C CZ  . ARG B 1 280 ? 92.890  140.152 90.799  1.00 60.77  ? 280 ARG B CZ  1 
ATOM   6462  N NH1 . ARG B 1 280 ? 92.477  139.620 89.661  1.00 57.67  ? 280 ARG B NH1 1 
ATOM   6463  N NH2 . ARG B 1 280 ? 92.675  139.518 91.938  1.00 57.95  ? 280 ARG B NH2 1 
ATOM   6464  N N   . LEU B 1 281 ? 89.217  141.098 94.611  1.00 54.01  ? 281 LEU B N   1 
ATOM   6465  C CA  . LEU B 1 281 ? 88.146  140.093 94.580  1.00 52.67  ? 281 LEU B CA  1 
ATOM   6466  C C   . LEU B 1 281 ? 86.994  140.353 95.555  1.00 52.16  ? 281 LEU B C   1 
ATOM   6467  O O   . LEU B 1 281 ? 85.875  139.904 95.313  1.00 55.13  ? 281 LEU B O   1 
ATOM   6468  C CB  . LEU B 1 281 ? 88.758  138.717 94.868  1.00 51.21  ? 281 LEU B CB  1 
ATOM   6469  C CG  . LEU B 1 281 ? 89.817  138.263 93.852  1.00 54.03  ? 281 LEU B CG  1 
ATOM   6470  C CD1 . LEU B 1 281 ? 90.448  136.980 94.360  1.00 55.20  ? 281 LEU B CD1 1 
ATOM   6471  C CD2 . LEU B 1 281 ? 89.218  138.001 92.475  1.00 52.03  ? 281 LEU B CD2 1 
ATOM   6472  N N   . CYS B 1 282 ? 87.241  141.077 96.642  1.00 53.10  ? 282 CYS B N   1 
ATOM   6473  C CA  . CYS B 1 282 ? 86.230  141.491 97.613  1.00 51.35  ? 282 CYS B CA  1 
ATOM   6474  C C   . CYS B 1 282 ? 86.564  142.889 98.172  1.00 54.30  ? 282 CYS B C   1 
ATOM   6475  O O   . CYS B 1 282 ? 86.731  143.053 99.381  1.00 57.03  ? 282 CYS B O   1 
ATOM   6476  C CB  . CYS B 1 282 ? 86.049  140.385 98.673  1.00 53.08  ? 282 CYS B CB  1 
ATOM   6477  S SG  . CYS B 1 282 ? 87.599  139.906 99.491  1.00 55.21  ? 282 CYS B SG  1 
ATOM   6478  N N   . PRO B 1 283 ? 86.649  143.936 97.326  1.00 58.04  ? 283 PRO B N   1 
ATOM   6479  C CA  . PRO B 1 283 ? 87.194  145.244 97.704  1.00 57.18  ? 283 PRO B CA  1 
ATOM   6480  C C   . PRO B 1 283 ? 86.382  145.979 98.783  1.00 57.37  ? 283 PRO B C   1 
ATOM   6481  O O   . PRO B 1 283 ? 86.917  146.827 99.493  1.00 57.58  ? 283 PRO B O   1 
ATOM   6482  C CB  . PRO B 1 283 ? 87.247  146.046 96.402  1.00 54.58  ? 283 PRO B CB  1 
ATOM   6483  C CG  . PRO B 1 283 ? 86.177  145.409 95.526  1.00 57.67  ? 283 PRO B CG  1 
ATOM   6484  C CD  . PRO B 1 283 ? 86.247  143.942 95.926  1.00 57.53  ? 283 PRO B CD  1 
ATOM   6485  N N   . THR B 1 284 ? 85.103  145.640 98.942  1.00 58.52  ? 284 THR B N   1 
ATOM   6486  C CA  . THR B 1 284 ? 84.241  146.139 100.023 1.00 59.03  ? 284 THR B CA  1 
ATOM   6487  C C   . THR B 1 284 ? 84.596  145.569 101.411 1.00 58.07  ? 284 THR B C   1 
ATOM   6488  O O   . THR B 1 284 ? 84.195  146.129 102.432 1.00 58.47  ? 284 THR B O   1 
ATOM   6489  C CB  . THR B 1 284 ? 82.766  145.891 99.655  1.00 61.76  ? 284 THR B CB  1 
ATOM   6490  O OG1 . THR B 1 284 ? 81.908  146.639 100.478 1.00 63.95  ? 284 THR B OG1 1 
ATOM   6491  C CG2 . THR B 1 284 ? 82.319  144.433 99.766  1.00 58.13  ? 284 THR B CG2 1 
ATOM   6492  N N   . VAL B 1 285 ? 85.365  144.477 101.486 1.00 54.61  ? 285 VAL B N   1 
ATOM   6493  C CA  . VAL B 1 285 ? 85.621  143.732 102.730 1.00 52.48  ? 285 VAL B CA  1 
ATOM   6494  C C   . VAL B 1 285 ? 87.001  144.038 103.306 1.00 52.63  ? 285 VAL B C   1 
ATOM   6495  O O   . VAL B 1 285 ? 88.028  143.864 102.652 1.00 53.61  ? 285 VAL B O   1 
ATOM   6496  C CB  . VAL B 1 285 ? 85.456  142.215 102.531 1.00 53.07  ? 285 VAL B CB  1 
ATOM   6497  C CG1 . VAL B 1 285 ? 85.653  141.462 103.847 1.00 52.30  ? 285 VAL B CG1 1 
ATOM   6498  C CG2 . VAL B 1 285 ? 84.064  141.875 102.004 1.00 52.40  ? 285 VAL B CG2 1 
ATOM   6499  N N   . GLN B 1 286 ? 87.023  144.442 104.575 1.00 51.26  ? 286 GLN B N   1 
ATOM   6500  C CA  . GLN B 1 286 ? 88.227  144.578 105.389 1.00 49.21  ? 286 GLN B CA  1 
ATOM   6501  C C   . GLN B 1 286 ? 88.620  143.214 105.988 1.00 47.29  ? 286 GLN B C   1 
ATOM   6502  O O   . GLN B 1 286 ? 88.169  142.847 107.071 1.00 47.30  ? 286 GLN B O   1 
ATOM   6503  C CB  . GLN B 1 286 ? 87.958  145.620 106.488 1.00 50.01  ? 286 GLN B CB  1 
ATOM   6504  C CG  . GLN B 1 286 ? 87.727  147.049 105.974 1.00 49.38  ? 286 GLN B CG  1 
ATOM   6505  C CD  . GLN B 1 286 ? 89.038  147.784 105.723 1.00 56.44  ? 286 GLN B CD  1 
ATOM   6506  O OE1 . GLN B 1 286 ? 89.549  147.845 104.615 1.00 55.17  ? 286 GLN B OE1 1 
ATOM   6507  N NE2 . GLN B 1 286 ? 89.634  148.359 106.742 1.00 54.56  ? 286 GLN B NE2 1 
ATOM   6508  N N   . LEU B 1 287 ? 89.462  142.439 105.297 1.00 41.88  ? 287 LEU B N   1 
ATOM   6509  C CA  . LEU B 1 287 ? 89.816  141.070 105.713 1.00 36.66  ? 287 LEU B CA  1 
ATOM   6510  C C   . LEU B 1 287 ? 90.529  140.997 107.072 1.00 42.31  ? 287 LEU B C   1 
ATOM   6511  O O   . LEU B 1 287 ? 90.364  140.031 107.809 1.00 43.55  ? 287 LEU B O   1 
ATOM   6512  C CB  . LEU B 1 287 ? 90.704  140.413 104.646 1.00 38.54  ? 287 LEU B CB  1 
ATOM   6513  C CG  . LEU B 1 287 ? 90.051  140.181 103.278 1.00 40.81  ? 287 LEU B CG  1 
ATOM   6514  C CD1 . LEU B 1 287 ? 91.099  139.612 102.330 1.00 38.96  ? 287 LEU B CD1 1 
ATOM   6515  C CD2 . LEU B 1 287 ? 88.891  139.196 103.347 1.00 41.07  ? 287 LEU B CD2 1 
ATOM   6516  N N   . GLU B 1 288 ? 91.291  142.024 107.434 1.00 39.27  ? 288 GLU B N   1 
ATOM   6517  C CA  . GLU B 1 288 ? 91.963  142.117 108.733 1.00 29.86  ? 288 GLU B CA  1 
ATOM   6518  C C   . GLU B 1 288 ? 91.056  142.581 109.878 1.00 35.20  ? 288 GLU B C   1 
ATOM   6519  O O   . GLU B 1 288 ? 91.497  142.611 111.019 1.00 44.90  ? 288 GLU B O   1 
ATOM   6520  C CB  . GLU B 1 288 ? 93.154  143.066 108.648 1.00 35.90  ? 288 GLU B CB  1 
ATOM   6521  C CG  . GLU B 1 288 ? 94.180  142.626 107.618 1.00 31.43  ? 288 GLU B CG  1 
ATOM   6522  C CD  . GLU B 1 288 ? 95.467  143.418 107.799 1.00 40.78  ? 288 GLU B CD  1 
ATOM   6523  O OE1 . GLU B 1 288 ? 95.420  144.665 107.763 1.00 47.11  ? 288 GLU B OE1 1 
ATOM   6524  O OE2 . GLU B 1 288 ? 96.539  142.807 107.975 1.00 38.59  ? 288 GLU B OE2 1 
ATOM   6525  N N   . GLU B 1 289 ? 89.807  142.965 109.619 1.00 38.07  ? 289 GLU B N   1 
ATOM   6526  C CA  . GLU B 1 289 ? 88.836  143.296 110.672 1.00 40.72  ? 289 GLU B CA  1 
ATOM   6527  C C   . GLU B 1 289 ? 87.970  142.095 111.074 1.00 43.23  ? 289 GLU B C   1 
ATOM   6528  O O   . GLU B 1 289 ? 87.231  142.168 112.054 1.00 48.39  ? 289 GLU B O   1 
ATOM   6529  C CB  . GLU B 1 289 ? 87.962  144.486 110.255 1.00 44.13  ? 289 GLU B CB  1 
ATOM   6530  C CG  . GLU B 1 289 ? 88.766  145.790 110.192 1.00 43.46  ? 289 GLU B CG  1 
ATOM   6531  C CD  . GLU B 1 289 ? 87.899  147.018 109.860 1.00 51.38  ? 289 GLU B CD  1 
ATOM   6532  O OE1 . GLU B 1 289 ? 86.707  147.055 110.236 1.00 50.78  ? 289 GLU B OE1 1 
ATOM   6533  O OE2 . GLU B 1 289 ? 88.424  147.960 109.233 1.00 54.53  ? 289 GLU B OE2 1 
ATOM   6534  N N   . ILE B 1 290 ? 88.059  140.979 110.345 1.00 42.16  ? 290 ILE B N   1 
ATOM   6535  C CA  . ILE B 1 290 ? 87.363  139.737 110.679 1.00 35.38  ? 290 ILE B CA  1 
ATOM   6536  C C   . ILE B 1 290 ? 87.958  139.170 111.972 1.00 33.93  ? 290 ILE B C   1 
ATOM   6537  O O   . ILE B 1 290 ? 89.163  138.953 112.071 1.00 39.00  ? 290 ILE B O   1 
ATOM   6538  C CB  . ILE B 1 290 ? 87.427  138.726 109.509 1.00 37.21  ? 290 ILE B CB  1 
ATOM   6539  C CG1 . ILE B 1 290 ? 86.771  139.308 108.239 1.00 33.88  ? 290 ILE B CG1 1 
ATOM   6540  C CG2 . ILE B 1 290 ? 86.737  137.410 109.908 1.00 36.23  ? 290 ILE B CG2 1 
ATOM   6541  C CD1 . ILE B 1 290 ? 87.011  138.497 106.970 1.00 36.59  ? 290 ILE B CD1 1 
ATOM   6542  N N   . SER B 1 291 ? 87.109  138.900 112.963 1.00 33.53  ? 291 SER B N   1 
ATOM   6543  C CA  . SER B 1 291 ? 87.504  138.302 114.238 1.00 27.98  ? 291 SER B CA  1 
ATOM   6544  C C   . SER B 1 291 ? 87.189  136.811 114.277 1.00 36.38  ? 291 SER B C   1 
ATOM   6545  O O   . SER B 1 291 ? 86.104  136.391 113.877 1.00 44.46  ? 291 SER B O   1 
ATOM   6546  C CB  . SER B 1 291 ? 86.824  139.007 115.408 1.00 28.48  ? 291 SER B CB  1 
ATOM   6547  O OG  . SER B 1 291 ? 87.341  140.308 115.547 1.00 37.22  ? 291 SER B OG  1 
ATOM   6548  N N   . ASN B 1 292 ? 88.117  136.002 114.770 1.00 31.91  ? 292 ASN B N   1 
ATOM   6549  C CA  . ASN B 1 292 ? 87.866  134.590 115.052 1.00 32.35  ? 292 ASN B CA  1 
ATOM   6550  C C   . ASN B 1 292 ? 86.961  134.404 116.294 1.00 29.53  ? 292 ASN B C   1 
ATOM   6551  O O   . ASN B 1 292 ? 86.516  135.377 116.904 1.00 39.16  ? 292 ASN B O   1 
ATOM   6552  C CB  . ASN B 1 292 ? 89.214  133.846 115.096 1.00 26.06  ? 292 ASN B CB  1 
ATOM   6553  C CG  . ASN B 1 292 ? 90.064  134.084 116.319 1.00 25.93  ? 292 ASN B CG  1 
ATOM   6554  O OD1 . ASN B 1 292 ? 89.663  134.708 117.285 1.00 33.55  ? 292 ASN B OD1 1 
ATOM   6555  N ND2 . ASN B 1 292 ? 91.255  133.564 116.329 1.00 28.64  ? 292 ASN B ND2 1 
ATOM   6556  N N   . HIS B 1 293 ? 86.667  133.169 116.703 1.00 34.59  ? 293 HIS B N   1 
ATOM   6557  C CA  . HIS B 1 293 ? 85.786  132.903 117.857 1.00 35.06  ? 293 HIS B CA  1 
ATOM   6558  C C   . HIS B 1 293 ? 86.338  133.394 119.201 1.00 33.97  ? 293 HIS B C   1 
ATOM   6559  O O   . HIS B 1 293 ? 85.565  133.623 120.126 1.00 40.06  ? 293 HIS B O   1 
ATOM   6560  C CB  . HIS B 1 293 ? 85.463  131.404 117.929 1.00 33.07  ? 293 HIS B CB  1 
ATOM   6561  C CG  . HIS B 1 293 ? 84.697  130.854 116.752 1.00 34.90  ? 293 HIS B CG  1 
ATOM   6562  N ND1 . HIS B 1 293 ? 84.497  129.499 116.503 1.00 42.46  ? 293 HIS B ND1 1 
ATOM   6563  C CD2 . HIS B 1 293 ? 84.040  131.572 115.796 1.00 34.43  ? 293 HIS B CD2 1 
ATOM   6564  C CE1 . HIS B 1 293 ? 83.751  129.427 115.391 1.00 40.23  ? 293 HIS B CE1 1 
ATOM   6565  N NE2 . HIS B 1 293 ? 83.465  130.659 114.947 1.00 36.34  ? 293 HIS B NE2 1 
ATOM   6566  N N   . GLN B 1 294 ? 87.654  133.598 119.322 1.00 37.59  ? 294 GLN B N   1 
ATOM   6567  C CA  . GLN B 1 294 ? 88.289  134.238 120.480 1.00 37.26  ? 294 GLN B CA  1 
ATOM   6568  C C   . GLN B 1 294 ? 88.224  135.781 120.441 1.00 41.81  ? 294 GLN B C   1 
ATOM   6569  O O   . GLN B 1 294 ? 88.759  136.442 121.329 1.00 43.28  ? 294 GLN B O   1 
ATOM   6570  C CB  . GLN B 1 294 ? 89.739  133.751 120.637 1.00 36.68  ? 294 GLN B CB  1 
ATOM   6571  C CG  . GLN B 1 294 ? 89.841  132.237 120.841 1.00 41.30  ? 294 GLN B CG  1 
ATOM   6572  C CD  . GLN B 1 294 ? 91.249  131.751 121.181 1.00 48.68  ? 294 GLN B CD  1 
ATOM   6573  O OE1 . GLN B 1 294 ? 92.156  132.506 121.505 1.00 49.02  ? 294 GLN B OE1 1 
ATOM   6574  N NE2 . GLN B 1 294 ? 91.487  130.462 121.139 1.00 44.33  ? 294 GLN B NE2 1 
ATOM   6575  N N   . GLY B 1 295 ? 87.597  136.373 119.418 1.00 38.61  ? 295 GLY B N   1 
ATOM   6576  C CA  . GLY B 1 295 ? 87.496  137.819 119.235 1.00 33.27  ? 295 GLY B CA  1 
ATOM   6577  C C   . GLY B 1 295 ? 88.776  138.473 118.710 1.00 38.98  ? 295 GLY B C   1 
ATOM   6578  O O   . GLY B 1 295 ? 88.975  139.667 118.911 1.00 44.31  ? 295 GLY B O   1 
ATOM   6579  N N   . LEU B 1 296 ? 89.663  137.710 118.071 1.00 33.55  ? 296 LEU B N   1 
ATOM   6580  C CA  . LEU B 1 296 ? 90.959  138.192 117.598 1.00 24.93  ? 296 LEU B CA  1 
ATOM   6581  C C   . LEU B 1 296 ? 90.942  138.402 116.084 1.00 22.90  ? 296 LEU B C   1 
ATOM   6582  O O   . LEU B 1 296 ? 90.559  137.520 115.323 1.00 31.16  ? 296 LEU B O   1 
ATOM   6583  C CB  . LEU B 1 296 ? 92.071  137.208 117.994 1.00 24.38  ? 296 LEU B CB  1 
ATOM   6584  C CG  . LEU B 1 296 ? 92.178  136.919 119.498 1.00 25.97  ? 296 LEU B CG  1 
ATOM   6585  C CD1 . LEU B 1 296 ? 93.073  135.712 119.714 1.00 30.68  ? 296 LEU B CD1 1 
ATOM   6586  C CD2 . LEU B 1 296 ? 92.768  138.083 120.276 1.00 23.43  ? 296 LEU B CD2 1 
ATOM   6587  N N   . THR B 1 297 ? 91.403  139.561 115.633 1.00 29.86  ? 297 THR B N   1 
ATOM   6588  C CA  . THR B 1 297 ? 91.822  139.803 114.250 1.00 24.33  ? 297 THR B CA  1 
ATOM   6589  C C   . THR B 1 297 ? 93.210  139.196 113.997 1.00 20.55  ? 297 THR B C   1 
ATOM   6590  O O   . THR B 1 297 ? 93.889  138.845 114.961 1.00 31.00  ? 297 THR B O   1 
ATOM   6591  C CB  . THR B 1 297 ? 91.851  141.309 113.976 1.00 27.18  ? 297 THR B CB  1 
ATOM   6592  O OG1 . THR B 1 297 ? 92.780  141.959 114.808 1.00 33.94  ? 297 THR B OG1 1 
ATOM   6593  C CG2 . THR B 1 297 ? 90.498  141.971 114.186 1.00 20.54  ? 297 THR B CG2 1 
ATOM   6594  N N   . PRO B 1 298 ? 93.698  139.066 112.751 1.00 18.71  ? 298 PRO B N   1 
ATOM   6595  C CA  . PRO B 1 298 ? 95.040  138.537 112.501 1.00 17.52  ? 298 PRO B CA  1 
ATOM   6596  C C   . PRO B 1 298 ? 96.174  139.265 113.251 1.00 17.44  ? 298 PRO B C   1 
ATOM   6597  O O   . PRO B 1 298 ? 97.066  138.606 113.769 1.00 22.84  ? 298 PRO B O   1 
ATOM   6598  C CB  . PRO B 1 298 ? 95.211  138.610 110.989 1.00 20.19  ? 298 PRO B CB  1 
ATOM   6599  C CG  . PRO B 1 298 ? 93.790  138.513 110.450 1.00 10.15  ? 298 PRO B CG  1 
ATOM   6600  C CD  . PRO B 1 298 ? 92.979  139.256 111.498 1.00 14.12  ? 298 PRO B CD  1 
ATOM   6601  N N   . LEU B 1 299 ? 96.125  140.597 113.399 1.00 17.48  ? 299 LEU B N   1 
ATOM   6602  C CA  . LEU B 1 299 ? 97.107  141.367 114.181 1.00 13.01  ? 299 LEU B CA  1 
ATOM   6603  C C   . LEU B 1 299 ? 97.036  141.075 115.688 1.00 22.21  ? 299 LEU B C   1 
ATOM   6604  O O   . LEU B 1 299 ? 98.063  140.902 116.336 1.00 22.81  ? 299 LEU B O   1 
ATOM   6605  C CB  . LEU B 1 299 ? 96.894  142.866 113.901 1.00 15.92  ? 299 LEU B CB  1 
ATOM   6606  C CG  . LEU B 1 299 ? 97.821  143.805 114.691 1.00 18.92  ? 299 LEU B CG  1 
ATOM   6607  C CD1 . LEU B 1 299 ? 99.288  143.669 114.307 1.00 16.51  ? 299 LEU B CD1 1 
ATOM   6608  C CD2 . LEU B 1 299 ? 97.398  145.250 114.486 1.00 17.57  ? 299 LEU B CD2 1 
ATOM   6609  N N   . LYS B 1 300 ? 95.828  140.980 116.249 1.00 23.63  ? 300 LYS B N   1 
ATOM   6610  C CA  . LYS B 1 300 ? 95.604  140.598 117.649 1.00 8.45   ? 300 LYS B CA  1 
ATOM   6611  C C   . LYS B 1 300 ? 96.014  139.155 117.930 1.00 18.42  ? 300 LYS B C   1 
ATOM   6612  O O   . LYS B 1 300 ? 96.575  138.877 118.980 1.00 19.93  ? 300 LYS B O   1 
ATOM   6613  C CB  . LYS B 1 300 ? 94.136  140.830 118.013 1.00 21.30  ? 300 LYS B CB  1 
ATOM   6614  C CG  . LYS B 1 300 ? 93.780  142.314 118.128 1.00 19.51  ? 300 LYS B CG  1 
ATOM   6615  C CD  . LYS B 1 300 ? 92.344  142.479 118.632 1.00 19.44  ? 300 LYS B CD  1 
ATOM   6616  C CE  . LYS B 1 300 ? 91.936  143.949 118.603 1.00 21.92  ? 300 LYS B CE  1 
ATOM   6617  N NZ  . LYS B 1 300 ? 90.616  144.165 119.241 1.00 30.28  ? 300 LYS B NZ  1 
ATOM   6618  N N   . LEU B 1 301 ? 95.786  138.237 116.993 1.00 25.60  ? 301 LEU B N   1 
ATOM   6619  C CA  . LEU B 1 301 ? 96.276  136.865 117.067 1.00 10.90  ? 301 LEU B CA  1 
ATOM   6620  C C   . LEU B 1 301 ? 97.804  136.792 116.960 1.00 17.34  ? 301 LEU B C   1 
ATOM   6621  O O   . LEU B 1 301 ? 98.422  136.042 117.704 1.00 26.60  ? 301 LEU B O   1 
ATOM   6622  C CB  . LEU B 1 301 ? 95.563  136.039 115.989 1.00 28.60  ? 301 LEU B CB  1 
ATOM   6623  C CG  . LEU B 1 301 ? 95.897  134.540 116.038 1.00 25.01  ? 301 LEU B CG  1 
ATOM   6624  C CD1 . LEU B 1 301 ? 95.325  133.879 117.282 1.00 22.47  ? 301 LEU B CD1 1 
ATOM   6625  C CD2 . LEU B 1 301 ? 95.308  133.848 114.821 1.00 18.00  ? 301 LEU B CD2 1 
ATOM   6626  N N   . ALA B 1 302 ? 98.440  137.599 116.111 1.00 21.02  ? 302 ALA B N   1 
ATOM   6627  C CA  . ALA B 1 302 ? 99.897  137.660 116.036 1.00 21.88  ? 302 ALA B CA  1 
ATOM   6628  C C   . ALA B 1 302 ? 100.514 138.173 117.346 1.00 18.90  ? 302 ALA B C   1 
ATOM   6629  O O   . ALA B 1 302 ? 101.488 137.607 117.828 1.00 21.27  ? 302 ALA B O   1 
ATOM   6630  C CB  . ALA B 1 302 ? 100.309 138.501 114.824 1.00 12.83  ? 302 ALA B CB  1 
ATOM   6631  N N   . ALA B 1 303 ? 99.897  139.177 117.977 1.00 22.88  ? 303 ALA B N   1 
ATOM   6632  C CA  . ALA B 1 303 ? 100.246 139.639 119.315 1.00 15.38  ? 303 ALA B CA  1 
ATOM   6633  C C   . ALA B 1 303 ? 100.018 138.564 120.396 1.00 24.60  ? 303 ALA B C   1 
ATOM   6634  O O   . ALA B 1 303 ? 100.896 138.332 121.218 1.00 29.84  ? 303 ALA B O   1 
ATOM   6635  C CB  . ALA B 1 303 ? 99.435  140.900 119.611 1.00 24.93  ? 303 ALA B CB  1 
ATOM   6636  N N   . LYS B 1 304 ? 98.874  137.868 120.408 1.00 29.96  ? 304 LYS B N   1 
ATOM   6637  C CA  . LYS B 1 304 ? 98.571  136.849 121.420 1.00 20.38  ? 304 LYS B CA  1 
ATOM   6638  C C   . LYS B 1 304 ? 99.507  135.654 121.342 1.00 18.54  ? 304 LYS B C   1 
ATOM   6639  O O   . LYS B 1 304 ? 100.030 135.204 122.355 1.00 32.35  ? 304 LYS B O   1 
ATOM   6640  C CB  . LYS B 1 304 ? 97.108  136.402 121.311 1.00 21.09  ? 304 LYS B CB  1 
ATOM   6641  C CG  . LYS B 1 304 ? 96.743  135.520 122.509 1.00 30.04  ? 304 LYS B CG  1 
ATOM   6642  C CD  . LYS B 1 304 ? 95.284  135.089 122.470 1.00 34.83  ? 304 LYS B CD  1 
ATOM   6643  C CE  . LYS B 1 304 ? 94.985  134.153 123.640 1.00 34.85  ? 304 LYS B CE  1 
ATOM   6644  N NZ  . LYS B 1 304 ? 93.568  133.720 123.646 1.00 36.77  ? 304 LYS B NZ  1 
ATOM   6645  N N   . GLU B 1 305 ? 99.739  135.139 120.145 1.00 28.13  ? 305 GLU B N   1 
ATOM   6646  C CA  . GLU B 1 305 ? 100.557 133.951 119.915 1.00 21.07  ? 305 GLU B CA  1 
ATOM   6647  C C   . GLU B 1 305 ? 102.064 134.254 119.843 1.00 25.61  ? 305 GLU B C   1 
ATOM   6648  O O   . GLU B 1 305 ? 102.860 133.351 119.604 1.00 33.40  ? 305 GLU B O   1 
ATOM   6649  C CB  . GLU B 1 305 ? 100.036 133.215 118.674 1.00 21.28  ? 305 GLU B CB  1 
ATOM   6650  C CG  . GLU B 1 305 ? 98.560  132.790 118.734 1.00 25.37  ? 305 GLU B CG  1 
ATOM   6651  C CD  . GLU B 1 305 ? 98.206  131.886 119.924 1.00 32.00  ? 305 GLU B CD  1 
ATOM   6652  O OE1 . GLU B 1 305 ? 99.096  131.171 120.440 1.00 36.97  ? 305 GLU B OE1 1 
ATOM   6653  O OE2 . GLU B 1 305 ? 97.029  131.866 120.336 1.00 36.71  ? 305 GLU B OE2 1 
ATOM   6654  N N   . GLY B 1 306 ? 102.479 135.504 120.059 1.00 11.72  ? 306 GLY B N   1 
ATOM   6655  C CA  . GLY B 1 306 ? 103.883 135.914 120.099 1.00 9.37   ? 306 GLY B CA  1 
ATOM   6656  C C   . GLY B 1 306 ? 104.606 135.843 118.757 1.00 19.24  ? 306 GLY B C   1 
ATOM   6657  O O   . GLY B 1 306 ? 105.807 135.588 118.716 1.00 30.45  ? 306 GLY B O   1 
ATOM   6658  N N   . LYS B 1 307 ? 103.887 136.011 117.643 1.00 27.57  ? 307 LYS B N   1 
ATOM   6659  C CA  . LYS B 1 307 ? 104.414 135.849 116.283 1.00 22.61  ? 307 LYS B CA  1 
ATOM   6660  C C   . LYS B 1 307 ? 105.069 137.143 115.827 1.00 20.17  ? 307 LYS B C   1 
ATOM   6661  O O   . LYS B 1 307 ? 104.543 137.854 114.985 1.00 23.49  ? 307 LYS B O   1 
ATOM   6662  C CB  . LYS B 1 307 ? 103.305 135.355 115.338 1.00 18.76  ? 307 LYS B CB  1 
ATOM   6663  C CG  . LYS B 1 307 ? 102.567 134.109 115.824 1.00 13.17  ? 307 LYS B CG  1 
ATOM   6664  C CD  . LYS B 1 307 ? 103.518 132.959 116.167 1.00 17.47  ? 307 LYS B CD  1 
ATOM   6665  C CE  . LYS B 1 307 ? 102.778 131.656 116.466 1.00 24.71  ? 307 LYS B CE  1 
ATOM   6666  N NZ  . LYS B 1 307 ? 102.309 130.974 115.239 1.00 21.56  ? 307 LYS B NZ  1 
ATOM   6667  N N   . ILE B 1 308 ? 106.186 137.494 116.447 1.00 24.81  ? 308 ILE B N   1 
ATOM   6668  C CA  . ILE B 1 308 ? 106.770 138.833 116.381 1.00 27.76  ? 308 ILE B CA  1 
ATOM   6669  C C   . ILE B 1 308 ? 107.145 139.283 114.966 1.00 25.90  ? 308 ILE B C   1 
ATOM   6670  O O   . ILE B 1 308 ? 107.018 140.461 114.649 1.00 30.17  ? 308 ILE B O   1 
ATOM   6671  C CB  . ILE B 1 308 ? 107.938 138.958 117.380 1.00 33.40  ? 308 ILE B CB  1 
ATOM   6672  C CG1 . ILE B 1 308 ? 108.449 140.407 117.374 1.00 35.40  ? 308 ILE B CG1 1 
ATOM   6673  C CG2 . ILE B 1 308 ? 109.077 137.967 117.106 1.00 25.71  ? 308 ILE B CG2 1 
ATOM   6674  C CD1 . ILE B 1 308 ? 109.344 140.738 118.554 1.00 26.87  ? 308 ILE B CD1 1 
ATOM   6675  N N   . GLU B 1 309 ? 107.574 138.376 114.094 1.00 33.00  ? 309 GLU B N   1 
ATOM   6676  C CA  . GLU B 1 309 ? 108.001 138.727 112.740 1.00 31.64  ? 309 GLU B CA  1 
ATOM   6677  C C   . GLU B 1 309 ? 106.821 139.143 111.843 1.00 28.67  ? 309 GLU B C   1 
ATOM   6678  O O   . GLU B 1 309 ? 106.871 140.195 111.210 1.00 33.10  ? 309 GLU B O   1 
ATOM   6679  C CB  . GLU B 1 309 ? 108.796 137.561 112.143 1.00 34.52  ? 309 GLU B CB  1 
ATOM   6680  C CG  . GLU B 1 309 ? 110.031 137.172 112.977 1.00 29.62  ? 309 GLU B CG  1 
ATOM   6681  C CD  . GLU B 1 309 ? 111.030 138.325 113.116 1.00 39.76  ? 309 GLU B CD  1 
ATOM   6682  O OE1 . GLU B 1 309 ? 111.345 138.976 112.097 1.00 38.84  ? 309 GLU B OE1 1 
ATOM   6683  O OE2 . GLU B 1 309 ? 111.487 138.637 114.238 1.00 42.35  ? 309 GLU B OE2 1 
ATOM   6684  N N   . ILE B 1 310 ? 105.725 138.380 111.837 1.00 20.17  ? 310 ILE B N   1 
ATOM   6685  C CA  . ILE B 1 310 ? 104.489 138.759 111.134 1.00 17.68  ? 310 ILE B CA  1 
ATOM   6686  C C   . ILE B 1 310 ? 103.736 139.880 111.862 1.00 21.24  ? 310 ILE B C   1 
ATOM   6687  O O   . ILE B 1 310 ? 103.134 140.725 111.213 1.00 34.42  ? 310 ILE B O   1 
ATOM   6688  C CB  . ILE B 1 310 ? 103.614 137.521 110.820 1.00 23.57  ? 310 ILE B CB  1 
ATOM   6689  C CG1 . ILE B 1 310 ? 102.362 137.819 109.969 1.00 31.86  ? 310 ILE B CG1 1 
ATOM   6690  C CG2 . ILE B 1 310 ? 103.130 136.805 112.083 1.00 20.72  ? 310 ILE B CG2 1 
ATOM   6691  C CD1 . ILE B 1 310 ? 102.653 138.428 108.598 1.00 28.47  ? 310 ILE B CD1 1 
ATOM   6692  N N   . PHE B 1 311 ? 103.821 139.962 113.189 1.00 25.94  ? 311 PHE B N   1 
ATOM   6693  C CA  . PHE B 1 311 ? 103.277 141.066 113.973 1.00 16.36  ? 311 PHE B CA  1 
ATOM   6694  C C   . PHE B 1 311 ? 103.933 142.398 113.599 1.00 19.12  ? 311 PHE B C   1 
ATOM   6695  O O   . PHE B 1 311 ? 103.229 143.323 113.213 1.00 23.88  ? 311 PHE B O   1 
ATOM   6696  C CB  . PHE B 1 311 ? 103.441 140.755 115.466 1.00 17.49  ? 311 PHE B CB  1 
ATOM   6697  C CG  . PHE B 1 311 ? 103.026 141.879 116.381 1.00 14.11  ? 311 PHE B CG  1 
ATOM   6698  C CD1 . PHE B 1 311 ? 101.665 142.169 116.551 1.00 16.57  ? 311 PHE B CD1 1 
ATOM   6699  C CD2 . PHE B 1 311 ? 103.996 142.664 117.029 1.00 13.75  ? 311 PHE B CD2 1 
ATOM   6700  C CE1 . PHE B 1 311 ? 101.274 143.267 117.322 1.00 18.21  ? 311 PHE B CE1 1 
ATOM   6701  C CE2 . PHE B 1 311 ? 103.601 143.747 117.826 1.00 16.90  ? 311 PHE B CE2 1 
ATOM   6702  C CZ  . PHE B 1 311 ? 102.244 144.058 117.954 1.00 22.51  ? 311 PHE B CZ  1 
ATOM   6703  N N   . ARG B 1 312 ? 105.271 142.477 113.614 1.00 19.19  ? 312 ARG B N   1 
ATOM   6704  C CA  . ARG B 1 312 ? 106.031 143.646 113.161 1.00 12.33  ? 312 ARG B CA  1 
ATOM   6705  C C   . ARG B 1 312 ? 105.687 144.006 111.724 1.00 27.71  ? 312 ARG B C   1 
ATOM   6706  O O   . ARG B 1 312 ? 105.464 145.174 111.434 1.00 34.01  ? 312 ARG B O   1 
ATOM   6707  C CB  . ARG B 1 312 ? 107.536 143.366 113.279 1.00 21.53  ? 312 ARG B CB  1 
ATOM   6708  C CG  . ARG B 1 312 ? 108.380 144.625 113.042 1.00 23.09  ? 312 ARG B CG  1 
ATOM   6709  C CD  . ARG B 1 312 ? 109.863 144.341 112.796 1.00 28.73  ? 312 ARG B CD  1 
ATOM   6710  N NE  . ARG B 1 312 ? 110.445 143.416 113.787 1.00 37.09  ? 312 ARG B NE  1 
ATOM   6711  C CZ  . ARG B 1 312 ? 110.783 142.154 113.584 1.00 36.45  ? 312 ARG B CZ  1 
ATOM   6712  N NH1 . ARG B 1 312 ? 111.192 141.415 114.567 1.00 30.38  ? 312 ARG B NH1 1 
ATOM   6713  N NH2 . ARG B 1 312 ? 110.718 141.609 112.411 1.00 29.65  ? 312 ARG B NH2 1 
ATOM   6714  N N   . HIS B 1 313 ? 105.620 143.012 110.838 1.00 25.52  ? 313 HIS B N   1 
ATOM   6715  C CA  . HIS B 1 313 ? 105.277 143.234 109.448 1.00 23.12  ? 313 HIS B CA  1 
ATOM   6716  C C   . HIS B 1 313 ? 103.905 143.882 109.298 1.00 23.51  ? 313 HIS B C   1 
ATOM   6717  O O   . HIS B 1 313 ? 103.851 144.945 108.650 1.00 32.28  ? 313 HIS B O   1 
ATOM   6718  C CB  . HIS B 1 313 ? 105.328 141.898 108.692 1.00 25.43  ? 313 HIS B CB  1 
ATOM   6719  C CG  . HIS B 1 313 ? 104.519 141.892 107.441 1.00 37.42  ? 313 HIS B CG  1 
ATOM   6720  N ND1 . HIS B 1 313 ? 104.977 142.450 106.264 1.00 22.71  ? 313 HIS B ND1 1 
ATOM   6721  C CD2 . HIS B 1 313 ? 103.286 141.407 107.179 1.00 39.50  ? 313 HIS B CD2 1 
ATOM   6722  C CE1 . HIS B 1 313 ? 104.061 142.306 105.329 1.00 26.56  ? 313 HIS B CE1 1 
ATOM   6723  N NE2 . HIS B 1 313 ? 103.015 141.668 105.865 1.00 37.15  ? 313 HIS B NE2 1 
ATOM   6724  N N   . ILE B 1 314 ? 102.835 143.307 109.858 1.00 19.37  ? 314 ILE B N   1 
ATOM   6725  C CA  . ILE B 1 314 ? 101.486 143.878 109.763 1.00 20.66  ? 314 ILE B CA  1 
ATOM   6726  C C   . ILE B 1 314 ? 101.497 145.293 110.361 1.00 19.02  ? 314 ILE B C   1 
ATOM   6727  O O   . ILE B 1 314 ? 101.013 146.215 109.678 1.00 29.86  ? 314 ILE B O   1 
ATOM   6728  C CB  . ILE B 1 314 ? 100.445 143.008 110.506 1.00 23.89  ? 314 ILE B CB  1 
ATOM   6729  C CG1 . ILE B 1 314 ? 100.344 141.601 109.915 1.00 23.14  ? 314 ILE B CG1 1 
ATOM   6730  C CG2 . ILE B 1 314 ? 99.080  143.718 110.543 1.00 19.76  ? 314 ILE B CG2 1 
ATOM   6731  C CD1 . ILE B 1 314 ? 99.400  140.687 110.662 1.00 22.05  ? 314 ILE B CD1 1 
ATOM   6732  N N   . LEU B 1 315 ? 102.030 145.459 111.576 1.00 23.75  ? 315 LEU B N   1 
ATOM   6733  C CA  . LEU B 1 315 ? 101.987 146.765 112.301 1.00 25.28  ? 315 LEU B CA  1 
ATOM   6734  C C   . LEU B 1 315 ? 102.720 147.883 111.550 1.00 27.09  ? 315 LEU B C   1 
ATOM   6735  O O   . LEU B 1 315 ? 102.257 149.018 111.617 1.00 25.44  ? 315 LEU B O   1 
ATOM   6736  C CB  . LEU B 1 315 ? 102.626 146.533 113.674 1.00 24.64  ? 315 LEU B CB  1 
ATOM   6737  C CG  . LEU B 1 315 ? 102.743 147.760 114.574 1.00 35.98  ? 315 LEU B CG  1 
ATOM   6738  C CD1 . LEU B 1 315 ? 101.368 148.226 115.028 1.00 32.44  ? 315 LEU B CD1 1 
ATOM   6739  C CD2 . LEU B 1 315 ? 103.624 147.451 115.774 1.00 25.32  ? 315 LEU B CD2 1 
ATOM   6740  N N   . GLN B 1 316 ? 103.803 147.606 110.826 1.00 33.59  ? 316 GLN B N   1 
ATOM   6741  C CA  . GLN B 1 316 ? 104.633 148.586 110.124 1.00 26.49  ? 316 GLN B CA  1 
ATOM   6742  C C   . GLN B 1 316 ? 104.458 148.580 108.593 1.00 21.29  ? 316 GLN B C   1 
ATOM   6743  O O   . GLN B 1 316 ? 105.283 149.148 107.878 1.00 32.62  ? 316 GLN B O   1 
ATOM   6744  C CB  . GLN B 1 316 ? 106.102 148.385 110.526 1.00 20.24  ? 316 GLN B CB  1 
ATOM   6745  C CG  . GLN B 1 316 ? 106.319 148.370 112.046 1.00 30.59  ? 316 GLN B CG  1 
ATOM   6746  C CD  . GLN B 1 316 ? 107.769 148.197 112.450 1.00 29.59  ? 316 GLN B CD  1 
ATOM   6747  O OE1 . GLN B 1 316 ? 108.648 147.869 111.668 1.00 32.37  ? 316 GLN B OE1 1 
ATOM   6748  N NE2 . GLN B 1 316 ? 108.070 148.397 113.708 1.00 24.62  ? 316 GLN B NE2 1 
ATOM   6749  N N   . ARG B 1 317 ? 103.421 147.896 108.090 1.00 22.22  ? 317 ARG B N   1 
ATOM   6750  C CA  . ARG B 1 317 ? 103.228 147.678 106.621 1.00 33.27  ? 317 ARG B CA  1 
ATOM   6751  C C   . ARG B 1 317 ? 102.966 148.961 105.827 1.00 30.60  ? 317 ARG B C   1 
ATOM   6752  O O   . ARG B 1 317 ? 102.132 149.771 106.275 1.00 32.73  ? 317 ARG B O   1 
ATOM   6753  C CB  . ARG B 1 317 ? 102.058 146.705 106.480 1.00 29.30  ? 317 ARG B CB  1 
ATOM   6754  C CG  . ARG B 1 317 ? 101.895 146.140 105.072 1.00 25.10  ? 317 ARG B CG  1 
ATOM   6755  C CD  . ARG B 1 317 ? 100.803 145.072 105.091 1.00 35.92  ? 317 ARG B CD  1 
ATOM   6756  N NE  . ARG B 1 317 ? 99.476  145.620 105.335 1.00 34.36  ? 317 ARG B NE  1 
ATOM   6757  C CZ  . ARG B 1 317 ? 98.911  145.724 106.533 1.00 28.56  ? 317 ARG B CZ  1 
ATOM   6758  N NH1 . ARG B 1 317 ? 97.699  146.235 106.653 1.00 30.45  ? 317 ARG B NH1 1 
ATOM   6759  N NH2 . ARG B 1 317 ? 99.561  145.313 107.608 1.00 40.48  ? 317 ARG B NH2 1 
ATOM   6760  N N   . GLU B 1 318 ? 103.653 149.132 104.694 1.00 34.63  ? 318 GLU B N   1 
ATOM   6761  C CA  . GLU B 1 318 ? 103.448 150.248 103.765 1.00 30.10  ? 318 GLU B CA  1 
ATOM   6762  C C   . GLU B 1 318 ? 103.438 149.806 102.291 1.00 36.37  ? 318 GLU B C   1 
ATOM   6763  O O   . GLU B 1 318 ? 104.231 148.958 101.887 1.00 38.19  ? 318 GLU B O   1 
ATOM   6764  C CB  . GLU B 1 318 ? 104.493 151.343 104.038 1.00 36.17  ? 318 GLU B CB  1 
ATOM   6765  C CG  . GLU B 1 318 ? 104.235 152.595 103.190 1.00 38.84  ? 318 GLU B CG  1 
ATOM   6766  C CD  . GLU B 1 318 ? 105.010 153.835 103.658 1.00 42.73  ? 318 GLU B CD  1 
ATOM   6767  O OE1 . GLU B 1 318 ? 106.059 153.694 104.325 1.00 46.32  ? 318 GLU B OE1 1 
ATOM   6768  O OE2 . GLU B 1 318 ? 104.592 154.956 103.298 1.00 38.33  ? 318 GLU B OE2 1 
ATOM   6769  N N   . PHE B 1 319 ? 102.565 150.416 101.483 1.00 44.55  ? 319 PHE B N   1 
ATOM   6770  C CA  . PHE B 1 319 ? 102.434 150.221 100.016 1.00 37.85  ? 319 PHE B CA  1 
ATOM   6771  C C   . PHE B 1 319 ? 102.168 151.569 99.305  1.00 46.51  ? 319 PHE B C   1 
ATOM   6772  O O   . PHE B 1 319 ? 101.900 152.570 99.998  1.00 47.26  ? 319 PHE B O   1 
ATOM   6773  C CB  . PHE B 1 319 ? 101.273 149.282 99.685  1.00 36.75  ? 319 PHE B CB  1 
ATOM   6774  C CG  . PHE B 1 319 ? 101.235 147.986 100.453 1.00 42.37  ? 319 PHE B CG  1 
ATOM   6775  C CD1 . PHE B 1 319 ? 102.129 146.967 100.171 1.00 45.23  ? 319 PHE B CD1 1 
ATOM   6776  C CD2 . PHE B 1 319 ? 100.287 147.777 101.441 1.00 41.95  ? 319 PHE B CD2 1 
ATOM   6777  C CE1 . PHE B 1 319 ? 102.087 145.772 100.871 1.00 40.34  ? 319 PHE B CE1 1 
ATOM   6778  C CE2 . PHE B 1 319 ? 100.243 146.582 102.140 1.00 40.43  ? 319 PHE B CE2 1 
ATOM   6779  C CZ  . PHE B 1 319 ? 101.143 145.581 101.853 1.00 40.88  ? 319 PHE B CZ  1 
ATOM   6780  N N   . SER B 1 320 ? 102.236 151.574 97.968  1.00 57.85  ? 320 SER B N   1 
ATOM   6781  C CA  . SER B 1 320 ? 102.070 152.750 97.087  1.00 56.28  ? 320 SER B CA  1 
ATOM   6782  C C   . SER B 1 320 ? 101.278 152.413 95.810  1.00 56.01  ? 320 SER B C   1 
ATOM   6783  O O   . SER B 1 320 ? 101.126 151.236 95.470  1.00 55.32  ? 320 SER B O   1 
ATOM   6784  C CB  . SER B 1 320 ? 103.445 153.332 96.754  1.00 53.75  ? 320 SER B CB  1 
ATOM   6785  O OG  . SER B 1 320 ? 104.258 152.375 96.106  1.00 58.82  ? 320 SER B OG  1 
ATOM   6786  N N   . GLY B 1 321 ? 100.723 153.405 95.121  1.00 57.85  ? 321 GLY B N   1 
ATOM   6787  C CA  . GLY B 1 321 ? 99.844  153.147 93.980  1.00 57.04  ? 321 GLY B CA  1 
ATOM   6788  C C   . GLY B 1 321 ? 98.532  152.483 94.420  1.00 57.26  ? 321 GLY B C   1 
ATOM   6789  O O   . GLY B 1 321 ? 97.881  152.997 95.334  1.00 58.67  ? 321 GLY B O   1 
ATOM   6790  N N   . PRO B 1 322 ? 98.109  151.359 93.814  1.00 56.12  ? 322 PRO B N   1 
ATOM   6791  C CA  . PRO B 1 322 ? 96.771  150.807 94.028  1.00 54.60  ? 322 PRO B CA  1 
ATOM   6792  C C   . PRO B 1 322 ? 96.566  150.220 95.431  1.00 53.71  ? 322 PRO B C   1 
ATOM   6793  O O   . PRO B 1 322 ? 95.456  150.233 95.955  1.00 54.93  ? 322 PRO B O   1 
ATOM   6794  C CB  . PRO B 1 322 ? 96.612  149.736 92.945  1.00 52.56  ? 322 PRO B CB  1 
ATOM   6795  C CG  . PRO B 1 322 ? 98.041  149.282 92.662  1.00 53.50  ? 322 PRO B CG  1 
ATOM   6796  C CD  . PRO B 1 322 ? 98.844  150.563 92.844  1.00 52.15  ? 322 PRO B CD  1 
ATOM   6797  N N   . TYR B 1 323 ? 97.639  149.719 96.052  1.00 48.59  ? 323 TYR B N   1 
ATOM   6798  C CA  . TYR B 1 323 ? 97.602  149.026 97.340  1.00 45.39  ? 323 TYR B CA  1 
ATOM   6799  C C   . TYR B 1 323 ? 97.872  149.922 98.550  1.00 49.38  ? 323 TYR B C   1 
ATOM   6800  O O   . TYR B 1 323 ? 97.849  149.441 99.674  1.00 49.70  ? 323 TYR B O   1 
ATOM   6801  C CB  . TYR B 1 323 ? 98.543  147.813 97.281  1.00 45.00  ? 323 TYR B CB  1 
ATOM   6802  C CG  . TYR B 1 323 ? 98.180  146.807 96.202  1.00 49.38  ? 323 TYR B CG  1 
ATOM   6803  C CD1 . TYR B 1 323 ? 96.865  146.304 96.106  1.00 48.18  ? 323 TYR B CD1 1 
ATOM   6804  C CD2 . TYR B 1 323 ? 99.162  146.371 95.294  1.00 47.60  ? 323 TYR B CD2 1 
ATOM   6805  C CE1 . TYR B 1 323 ? 96.534  145.382 95.098  1.00 46.48  ? 323 TYR B CE1 1 
ATOM   6806  C CE2 . TYR B 1 323 ? 98.836  145.440 94.293  1.00 45.79  ? 323 TYR B CE2 1 
ATOM   6807  C CZ  . TYR B 1 323 ? 97.522  144.947 94.193  1.00 50.01  ? 323 TYR B CZ  1 
ATOM   6808  O OH  . TYR B 1 323 ? 97.209  144.026 93.244  1.00 50.53  ? 323 TYR B OH  1 
ATOM   6809  N N   . GLN B 1 324 ? 98.089  151.222 98.359  1.00 48.14  ? 324 GLN B N   1 
ATOM   6810  C CA  . GLN B 1 324 ? 98.357  152.163 99.447  1.00 42.85  ? 324 GLN B CA  1 
ATOM   6811  C C   . GLN B 1 324 ? 97.328  152.103 100.601 1.00 44.68  ? 324 GLN B C   1 
ATOM   6812  O O   . GLN B 1 324 ? 97.774  152.093 101.749 1.00 43.91  ? 324 GLN B O   1 
ATOM   6813  C CB  . GLN B 1 324 ? 98.561  153.564 98.849  1.00 46.74  ? 324 GLN B CB  1 
ATOM   6814  C CG  . GLN B 1 324 ? 99.105  154.609 99.837  1.00 47.44  ? 324 GLN B CG  1 
ATOM   6815  C CD  . GLN B 1 324 ? 98.040  155.459 100.520 1.00 47.99  ? 324 GLN B CD  1 
ATOM   6816  O OE1 . GLN B 1 324 ? 96.852  155.185 100.495 1.00 50.34  ? 324 GLN B OE1 1 
ATOM   6817  N NE2 . GLN B 1 324 ? 98.435  156.537 101.151 1.00 46.16  ? 324 GLN B NE2 1 
ATOM   6818  N N   . PRO B 1 325 ? 96.007  151.938 100.372 1.00 46.69  ? 325 PRO B N   1 
ATOM   6819  C CA  . PRO B 1 325 ? 95.027  151.764 101.448 1.00 45.60  ? 325 PRO B CA  1 
ATOM   6820  C C   . PRO B 1 325 ? 95.236  150.522 102.330 1.00 41.63  ? 325 PRO B C   1 
ATOM   6821  O O   . PRO B 1 325 ? 94.747  150.483 103.456 1.00 45.69  ? 325 PRO B O   1 
ATOM   6822  C CB  . PRO B 1 325 ? 93.660  151.691 100.760 1.00 45.82  ? 325 PRO B CB  1 
ATOM   6823  C CG  . PRO B 1 325 ? 93.883  152.406 99.439  1.00 45.17  ? 325 PRO B CG  1 
ATOM   6824  C CD  . PRO B 1 325 ? 95.315  152.024 99.097  1.00 38.94  ? 325 PRO B CD  1 
ATOM   6825  N N   . LEU B 1 326 ? 95.968  149.505 101.872 1.00 41.86  ? 326 LEU B N   1 
ATOM   6826  C CA  . LEU B 1 326 ? 96.323  148.337 102.684 1.00 36.72  ? 326 LEU B CA  1 
ATOM   6827  C C   . LEU B 1 326 ? 97.472  148.618 103.667 1.00 38.91  ? 326 LEU B C   1 
ATOM   6828  O O   . LEU B 1 326 ? 97.841  147.744 104.441 1.00 46.61  ? 326 LEU B O   1 
ATOM   6829  C CB  . LEU B 1 326 ? 96.668  147.144 101.774 1.00 40.92  ? 326 LEU B CB  1 
ATOM   6830  C CG  . LEU B 1 326 ? 95.543  146.618 100.875 1.00 38.39  ? 326 LEU B CG  1 
ATOM   6831  C CD1 . LEU B 1 326 ? 96.140  145.593 99.913  1.00 38.11  ? 326 LEU B CD1 1 
ATOM   6832  C CD2 . LEU B 1 326 ? 94.449  145.953 101.698 1.00 36.75  ? 326 LEU B CD2 1 
ATOM   6833  N N   . SER B 1 327 ? 98.073  149.804 103.657 1.00 36.25  ? 327 SER B N   1 
ATOM   6834  C CA  . SER B 1 327 ? 99.134  150.187 104.594 1.00 29.97  ? 327 SER B CA  1 
ATOM   6835  C C   . SER B 1 327 ? 98.609  150.382 106.017 1.00 31.75  ? 327 SER B C   1 
ATOM   6836  O O   . SER B 1 327 ? 97.478  150.816 106.218 1.00 32.83  ? 327 SER B O   1 
ATOM   6837  C CB  . SER B 1 327 ? 99.808  151.487 104.156 1.00 32.56  ? 327 SER B CB  1 
ATOM   6838  O OG  . SER B 1 327 ? 100.187 151.433 102.804 1.00 36.29  ? 327 SER B OG  1 
ATOM   6839  N N   . ARG B 1 328 ? 99.459  150.121 107.015 1.00 31.08  ? 328 ARG B N   1 
ATOM   6840  C CA  . ARG B 1 328 ? 99.313  150.610 108.395 1.00 23.68  ? 328 ARG B CA  1 
ATOM   6841  C C   . ARG B 1 328 ? 100.311 151.718 108.741 1.00 28.08  ? 328 ARG B C   1 
ATOM   6842  O O   . ARG B 1 328 ? 100.042 152.501 109.637 1.00 25.13  ? 328 ARG B O   1 
ATOM   6843  C CB  . ARG B 1 328 ? 99.433  149.453 109.397 1.00 25.11  ? 328 ARG B CB  1 
ATOM   6844  C CG  . ARG B 1 328 ? 98.229  148.505 109.358 1.00 19.59  ? 328 ARG B CG  1 
ATOM   6845  C CD  . ARG B 1 328 ? 98.148  147.607 110.598 1.00 29.13  ? 328 ARG B CD  1 
ATOM   6846  N NE  . ARG B 1 328 ? 97.774  148.355 111.812 1.00 24.99  ? 328 ARG B NE  1 
ATOM   6847  C CZ  . ARG B 1 328 ? 96.567  148.482 112.313 1.00 25.27  ? 328 ARG B CZ  1 
ATOM   6848  N NH1 . ARG B 1 328 ? 96.348  149.303 113.285 1.00 24.88  ? 328 ARG B NH1 1 
ATOM   6849  N NH2 . ARG B 1 328 ? 95.549  147.830 111.846 1.00 31.15  ? 328 ARG B NH2 1 
ATOM   6850  N N   . LYS B 1 329 ? 101.431 151.810 108.031 1.00 28.15  ? 329 LYS B N   1 
ATOM   6851  C CA  . LYS B 1 329 ? 102.418 152.885 108.124 1.00 25.81  ? 329 LYS B CA  1 
ATOM   6852  C C   . LYS B 1 329 ? 102.336 153.743 106.866 1.00 24.79  ? 329 LYS B C   1 
ATOM   6853  O O   . LYS B 1 329 ? 102.311 153.210 105.768 1.00 33.60  ? 329 LYS B O   1 
ATOM   6854  C CB  . LYS B 1 329 ? 103.799 152.250 108.306 1.00 22.68  ? 329 LYS B CB  1 
ATOM   6855  C CG  . LYS B 1 329 ? 104.929 153.266 108.478 1.00 18.43  ? 329 LYS B CG  1 
ATOM   6856  C CD  . LYS B 1 329 ? 106.270 152.541 108.527 1.00 23.14  ? 329 LYS B CD  1 
ATOM   6857  C CE  . LYS B 1 329 ? 107.409 153.540 108.713 1.00 24.53  ? 329 LYS B CE  1 
ATOM   6858  N NZ  . LYS B 1 329 ? 108.719 152.860 108.812 1.00 28.35  ? 329 LYS B NZ  1 
ATOM   6859  N N   . PHE B 1 330 ? 102.320 155.059 107.019 1.00 25.43  ? 330 PHE B N   1 
ATOM   6860  C CA  . PHE B 1 330 ? 102.343 156.027 105.928 1.00 20.80  ? 330 PHE B CA  1 
ATOM   6861  C C   . PHE B 1 330 ? 103.514 156.986 106.123 1.00 26.90  ? 330 PHE B C   1 
ATOM   6862  O O   . PHE B 1 330 ? 103.543 157.704 107.117 1.00 34.63  ? 330 PHE B O   1 
ATOM   6863  C CB  . PHE B 1 330 ? 101.012 156.791 105.890 1.00 24.02  ? 330 PHE B CB  1 
ATOM   6864  C CG  . PHE B 1 330 ? 99.786  155.905 105.819 1.00 35.48  ? 330 PHE B CG  1 
ATOM   6865  C CD1 . PHE B 1 330 ? 99.194  155.413 106.998 1.00 36.04  ? 330 PHE B CD1 1 
ATOM   6866  C CD2 . PHE B 1 330 ? 99.268  155.535 104.570 1.00 29.88  ? 330 PHE B CD2 1 
ATOM   6867  C CE1 . PHE B 1 330 ? 98.106  154.535 106.923 1.00 32.97  ? 330 PHE B CE1 1 
ATOM   6868  C CE2 . PHE B 1 330 ? 98.167  154.674 104.493 1.00 29.71  ? 330 PHE B CE2 1 
ATOM   6869  C CZ  . PHE B 1 330 ? 97.598  154.165 105.669 1.00 33.65  ? 330 PHE B CZ  1 
ATOM   6870  N N   . THR B 1 331 ? 104.470 157.053 105.205 1.00 37.38  ? 331 THR B N   1 
ATOM   6871  C CA  . THR B 1 331 ? 105.501 158.100 105.247 1.00 27.60  ? 331 THR B CA  1 
ATOM   6872  C C   . THR B 1 331 ? 104.872 159.474 105.019 1.00 26.87  ? 331 THR B C   1 
ATOM   6873  O O   . THR B 1 331 ? 104.099 159.675 104.088 1.00 35.26  ? 331 THR B O   1 
ATOM   6874  C CB  . THR B 1 331 ? 106.656 157.813 104.284 1.00 30.41  ? 331 THR B CB  1 
ATOM   6875  O OG1 . THR B 1 331 ? 107.692 158.720 104.551 1.00 30.29  ? 331 THR B OG1 1 
ATOM   6876  C CG2 . THR B 1 331 ? 106.329 157.957 102.800 1.00 39.58  ? 331 THR B CG2 1 
ATOM   6877  N N   . GLU B 1 332 ? 105.153 160.426 105.897 1.00 33.92  ? 332 GLU B N   1 
ATOM   6878  C CA  . GLU B 1 332 ? 104.628 161.785 105.824 1.00 32.38  ? 332 GLU B CA  1 
ATOM   6879  C C   . GLU B 1 332 ? 105.623 162.724 105.138 1.00 34.65  ? 332 GLU B C   1 
ATOM   6880  O O   . GLU B 1 332 ? 105.253 163.461 104.227 1.00 41.90  ? 332 GLU B O   1 
ATOM   6881  C CB  . GLU B 1 332 ? 104.279 162.253 107.237 1.00 32.51  ? 332 GLU B CB  1 
ATOM   6882  C CG  . GLU B 1 332 ? 103.512 163.576 107.215 1.00 37.65  ? 332 GLU B CG  1 
ATOM   6883  C CD  . GLU B 1 332 ? 102.977 163.931 108.602 1.00 45.11  ? 332 GLU B CD  1 
ATOM   6884  O OE1 . GLU B 1 332 ? 103.700 163.735 109.595 1.00 41.83  ? 332 GLU B OE1 1 
ATOM   6885  O OE2 . GLU B 1 332 ? 101.838 164.443 108.720 1.00 48.48  ? 332 GLU B OE2 1 
ATOM   6886  N N   . TRP B 1 333 ? 106.895 162.648 105.529 1.00 34.79  ? 333 TRP B N   1 
ATOM   6887  C CA  . TRP B 1 333 ? 108.030 163.221 104.807 1.00 30.29  ? 333 TRP B CA  1 
ATOM   6888  C C   . TRP B 1 333 ? 109.334 162.511 105.174 1.00 30.89  ? 333 TRP B C   1 
ATOM   6889  O O   . TRP B 1 333 ? 109.452 161.876 106.220 1.00 35.80  ? 333 TRP B O   1 
ATOM   6890  C CB  . TRP B 1 333 ? 108.134 164.737 105.033 1.00 26.23  ? 333 TRP B CB  1 
ATOM   6891  C CG  . TRP B 1 333 ? 108.288 165.239 106.435 1.00 28.35  ? 333 TRP B CG  1 
ATOM   6892  C CD1 . TRP B 1 333 ? 107.274 165.682 107.207 1.00 30.22  ? 333 TRP B CD1 1 
ATOM   6893  C CD2 . TRP B 1 333 ? 109.500 165.414 107.232 1.00 33.81  ? 333 TRP B CD2 1 
ATOM   6894  N NE1 . TRP B 1 333 ? 107.770 166.137 108.406 1.00 33.66  ? 333 TRP B NE1 1 
ATOM   6895  C CE2 . TRP B 1 333 ? 109.139 166.041 108.461 1.00 32.15  ? 333 TRP B CE2 1 
ATOM   6896  C CE3 . TRP B 1 333 ? 110.871 165.138 107.044 1.00 33.16  ? 333 TRP B CE3 1 
ATOM   6897  C CZ2 . TRP B 1 333 ? 110.081 166.407 109.428 1.00 27.43  ? 333 TRP B CZ2 1 
ATOM   6898  C CZ3 . TRP B 1 333 ? 111.819 165.453 108.033 1.00 32.88  ? 333 TRP B CZ3 1 
ATOM   6899  C CH2 . TRP B 1 333 ? 111.429 166.103 109.215 1.00 32.98  ? 333 TRP B CH2 1 
ATOM   6900  N N   . CYS B 1 334 ? 110.329 162.613 104.300 1.00 39.47  ? 334 CYS B N   1 
ATOM   6901  C CA  . CYS B 1 334 ? 111.660 162.058 104.494 1.00 33.46  ? 334 CYS B CA  1 
ATOM   6902  C C   . CYS B 1 334 ? 112.704 163.080 104.031 1.00 35.78  ? 334 CYS B C   1 
ATOM   6903  O O   . CYS B 1 334 ? 112.605 163.603 102.925 1.00 44.07  ? 334 CYS B O   1 
ATOM   6904  C CB  . CYS B 1 334 ? 111.706 160.732 103.727 1.00 33.36  ? 334 CYS B CB  1 
ATOM   6905  S SG  . CYS B 1 334 ? 113.282 159.889 103.963 1.00 58.05  ? 334 CYS B SG  1 
ATOM   6906  N N   . TYR B 1 335 ? 113.703 163.379 104.856 1.00 30.38  ? 335 TYR B N   1 
ATOM   6907  C CA  . TYR B 1 335 ? 114.717 164.394 104.572 1.00 30.98  ? 335 TYR B CA  1 
ATOM   6908  C C   . TYR B 1 335 ? 116.037 163.988 105.227 1.00 34.11  ? 335 TYR B C   1 
ATOM   6909  O O   . TYR B 1 335 ? 116.177 163.989 106.449 1.00 36.00  ? 335 TYR B O   1 
ATOM   6910  C CB  . TYR B 1 335 ? 114.229 165.773 105.034 1.00 34.36  ? 335 TYR B CB  1 
ATOM   6911  C CG  . TYR B 1 335 ? 115.136 166.930 104.673 1.00 33.63  ? 335 TYR B CG  1 
ATOM   6912  C CD1 . TYR B 1 335 ? 116.175 167.308 105.537 1.00 34.68  ? 335 TYR B CD1 1 
ATOM   6913  C CD2 . TYR B 1 335 ? 114.925 167.652 103.487 1.00 34.02  ? 335 TYR B CD2 1 
ATOM   6914  C CE1 . TYR B 1 335 ? 117.024 168.383 105.203 1.00 29.85  ? 335 TYR B CE1 1 
ATOM   6915  C CE2 . TYR B 1 335 ? 115.781 168.714 103.138 1.00 35.97  ? 335 TYR B CE2 1 
ATOM   6916  C CZ  . TYR B 1 335 ? 116.833 169.080 103.997 1.00 36.22  ? 335 TYR B CZ  1 
ATOM   6917  O OH  . TYR B 1 335 ? 117.651 170.110 103.668 1.00 36.21  ? 335 TYR B OH  1 
ATOM   6918  N N   . GLY B 1 336 ? 117.009 163.583 104.418 1.00 37.97  ? 336 GLY B N   1 
ATOM   6919  C CA  . GLY B 1 336 ? 118.262 163.031 104.904 1.00 29.88  ? 336 GLY B CA  1 
ATOM   6920  C C   . GLY B 1 336 ? 118.029 161.775 105.753 1.00 31.06  ? 336 GLY B C   1 
ATOM   6921  O O   . GLY B 1 336 ? 117.224 160.924 105.372 1.00 40.15  ? 336 GLY B O   1 
ATOM   6922  N N   . PRO B 1 337 ? 118.682 161.640 106.918 1.00 32.92  ? 337 PRO B N   1 
ATOM   6923  C CA  . PRO B 1 337 ? 118.537 160.485 107.801 1.00 32.92  ? 337 PRO B CA  1 
ATOM   6924  C C   . PRO B 1 337 ? 117.199 160.436 108.552 1.00 35.80  ? 337 PRO B C   1 
ATOM   6925  O O   . PRO B 1 337 ? 116.973 159.496 109.305 1.00 36.84  ? 337 PRO B O   1 
ATOM   6926  C CB  . PRO B 1 337 ? 119.725 160.585 108.753 1.00 29.27  ? 337 PRO B CB  1 
ATOM   6927  C CG  . PRO B 1 337 ? 119.945 162.090 108.869 1.00 31.07  ? 337 PRO B CG  1 
ATOM   6928  C CD  . PRO B 1 337 ? 119.619 162.591 107.476 1.00 30.80  ? 337 PRO B CD  1 
ATOM   6929  N N   . VAL B 1 338 ? 116.320 161.427 108.380 1.00 36.91  ? 338 VAL B N   1 
ATOM   6930  C CA  . VAL B 1 338 ? 115.056 161.561 109.108 1.00 32.08  ? 338 VAL B CA  1 
ATOM   6931  C C   . VAL B 1 338 ? 113.877 161.089 108.257 1.00 34.98  ? 338 VAL B C   1 
ATOM   6932  O O   . VAL B 1 338 ? 113.651 161.595 107.161 1.00 35.76  ? 338 VAL B O   1 
ATOM   6933  C CB  . VAL B 1 338 ? 114.829 163.016 109.560 1.00 36.95  ? 338 VAL B CB  1 
ATOM   6934  C CG1 . VAL B 1 338 ? 113.611 163.122 110.485 1.00 32.48  ? 338 VAL B CG1 1 
ATOM   6935  C CG2 . VAL B 1 338 ? 116.055 163.580 110.289 1.00 33.46  ? 338 VAL B CG2 1 
ATOM   6936  N N   . ARG B 1 339 ? 113.093 160.151 108.791 1.00 35.48  ? 339 ARG B N   1 
ATOM   6937  C CA  . ARG B 1 339 ? 111.788 159.714 108.272 1.00 27.93  ? 339 ARG B CA  1 
ATOM   6938  C C   . ARG B 1 339 ? 110.710 160.059 109.281 1.00 27.60  ? 339 ARG B C   1 
ATOM   6939  O O   . ARG B 1 339 ? 110.770 159.606 110.416 1.00 33.31  ? 339 ARG B O   1 
ATOM   6940  C CB  . ARG B 1 339 ? 111.804 158.202 108.013 1.00 34.42  ? 339 ARG B CB  1 
ATOM   6941  C CG  . ARG B 1 339 ? 112.576 157.850 106.746 1.00 37.98  ? 339 ARG B CG  1 
ATOM   6942  C CD  . ARG B 1 339 ? 112.625 156.339 106.521 1.00 36.89  ? 339 ARG B CD  1 
ATOM   6943  N NE  . ARG B 1 339 ? 113.267 156.013 105.234 1.00 40.28  ? 339 ARG B NE  1 
ATOM   6944  C CZ  . ARG B 1 339 ? 112.688 155.918 104.056 1.00 46.29  ? 339 ARG B CZ  1 
ATOM   6945  N NH1 . ARG B 1 339 ? 113.394 155.647 102.998 1.00 44.76  ? 339 ARG B NH1 1 
ATOM   6946  N NH2 . ARG B 1 339 ? 111.404 156.071 103.891 1.00 44.45  ? 339 ARG B NH2 1 
ATOM   6947  N N   . VAL B 1 340 ? 109.690 160.798 108.877 1.00 27.34  ? 340 VAL B N   1 
ATOM   6948  C CA  . VAL B 1 340 ? 108.491 161.011 109.688 1.00 26.58  ? 340 VAL B CA  1 
ATOM   6949  C C   . VAL B 1 340 ? 107.357 160.189 109.104 1.00 28.65  ? 340 VAL B C   1 
ATOM   6950  O O   . VAL B 1 340 ? 107.048 160.307 107.926 1.00 28.79  ? 340 VAL B O   1 
ATOM   6951  C CB  . VAL B 1 340 ? 108.149 162.500 109.804 1.00 25.84  ? 340 VAL B CB  1 
ATOM   6952  C CG1 . VAL B 1 340 ? 106.901 162.709 110.661 1.00 24.74  ? 340 VAL B CG1 1 
ATOM   6953  C CG2 . VAL B 1 340 ? 109.320 163.233 110.454 1.00 24.82  ? 340 VAL B CG2 1 
ATOM   6954  N N   . SER B 1 341 ? 106.754 159.328 109.915 1.00 32.48  ? 341 SER B N   1 
ATOM   6955  C CA  . SER B 1 341 ? 105.684 158.421 109.501 1.00 25.77  ? 341 SER B CA  1 
ATOM   6956  C C   . SER B 1 341 ? 104.468 158.551 110.395 1.00 24.67  ? 341 SER B C   1 
ATOM   6957  O O   . SER B 1 341 ? 104.594 158.759 111.593 1.00 27.60  ? 341 SER B O   1 
ATOM   6958  C CB  . SER B 1 341 ? 106.147 156.968 109.524 1.00 30.97  ? 341 SER B CB  1 
ATOM   6959  O OG  . SER B 1 341 ? 107.247 156.772 108.666 1.00 35.52  ? 341 SER B OG  1 
ATOM   6960  N N   . LEU B 1 342 ? 103.291 158.343 109.827 1.00 25.72  ? 342 LEU B N   1 
ATOM   6961  C CA  . LEU B 1 342 ? 102.053 158.101 110.554 1.00 25.86  ? 342 LEU B CA  1 
ATOM   6962  C C   . LEU B 1 342 ? 101.810 156.594 110.641 1.00 22.68  ? 342 LEU B C   1 
ATOM   6963  O O   . LEU B 1 342 ? 101.817 155.911 109.625 1.00 25.10  ? 342 LEU B O   1 
ATOM   6964  C CB  . LEU B 1 342 ? 100.894 158.780 109.814 1.00 29.61  ? 342 LEU B CB  1 
ATOM   6965  C CG  . LEU B 1 342 ? 100.949 160.312 109.770 1.00 27.78  ? 342 LEU B CG  1 
ATOM   6966  C CD1 . LEU B 1 342 ? 99.795  160.832 108.915 1.00 28.52  ? 342 LEU B CD1 1 
ATOM   6967  C CD2 . LEU B 1 342 ? 100.843 160.924 111.161 1.00 24.13  ? 342 LEU B CD2 1 
ATOM   6968  N N   . TYR B 1 343 ? 101.572 156.071 111.835 1.00 30.00  ? 343 TYR B N   1 
ATOM   6969  C CA  . TYR B 1 343 ? 101.151 154.689 112.058 1.00 20.08  ? 343 TYR B CA  1 
ATOM   6970  C C   . TYR B 1 343 ? 99.691  154.617 112.490 1.00 22.39  ? 343 TYR B C   1 
ATOM   6971  O O   . TYR B 1 343 ? 99.282  155.304 113.417 1.00 27.10  ? 343 TYR B O   1 
ATOM   6972  C CB  . TYR B 1 343 ? 102.013 154.033 113.127 1.00 15.35  ? 343 TYR B CB  1 
ATOM   6973  C CG  . TYR B 1 343 ? 103.436 153.732 112.726 1.00 17.42  ? 343 TYR B CG  1 
ATOM   6974  C CD1 . TYR B 1 343 ? 104.450 154.687 112.901 1.00 16.41  ? 343 TYR B CD1 1 
ATOM   6975  C CD2 . TYR B 1 343 ? 103.748 152.453 112.240 1.00 14.89  ? 343 TYR B CD2 1 
ATOM   6976  C CE1 . TYR B 1 343 ? 105.788 154.345 112.628 1.00 12.58  ? 343 TYR B CE1 1 
ATOM   6977  C CE2 . TYR B 1 343 ? 105.079 152.112 111.981 1.00 14.83  ? 343 TYR B CE2 1 
ATOM   6978  C CZ  . TYR B 1 343 ? 106.105 153.048 112.191 1.00 21.08  ? 343 TYR B CZ  1 
ATOM   6979  O OH  . TYR B 1 343 ? 107.390 152.689 111.952 1.00 32.08  ? 343 TYR B OH  1 
ATOM   6980  N N   . ASP B 1 344 ? 98.921  153.749 111.858 1.00 25.80  ? 344 ASP B N   1 
ATOM   6981  C CA  . ASP B 1 344 ? 97.535  153.431 112.185 1.00 27.02  ? 344 ASP B CA  1 
ATOM   6982  C C   . ASP B 1 344 ? 97.421  152.729 113.554 1.00 27.95  ? 344 ASP B C   1 
ATOM   6983  O O   . ASP B 1 344 ? 97.932  151.623 113.744 1.00 35.52  ? 344 ASP B O   1 
ATOM   6984  C CB  . ASP B 1 344 ? 97.021  152.567 111.026 1.00 22.53  ? 344 ASP B CB  1 
ATOM   6985  C CG  . ASP B 1 344 ? 95.574  152.097 111.125 1.00 30.51  ? 344 ASP B CG  1 
ATOM   6986  O OD1 . ASP B 1 344 ? 94.925  152.273 112.175 1.00 38.11  ? 344 ASP B OD1 1 
ATOM   6987  O OD2 . ASP B 1 344 ? 95.094  151.516 110.130 1.00 31.30  ? 344 ASP B OD2 1 
ATOM   6988  N N   . LEU B 1 345 ? 96.736  153.360 114.508 1.00 20.36  ? 345 LEU B N   1 
ATOM   6989  C CA  . LEU B 1 345 ? 96.532  152.846 115.865 1.00 21.61  ? 345 LEU B CA  1 
ATOM   6990  C C   . LEU B 1 345 ? 95.218  152.086 116.084 1.00 24.73  ? 345 LEU B C   1 
ATOM   6991  O O   . LEU B 1 345 ? 94.922  151.718 117.218 1.00 36.33  ? 345 LEU B O   1 
ATOM   6992  C CB  . LEU B 1 345 ? 96.637  154.004 116.871 1.00 28.45  ? 345 LEU B CB  1 
ATOM   6993  C CG  . LEU B 1 345 ? 98.015  154.651 117.039 1.00 25.07  ? 345 LEU B CG  1 
ATOM   6994  C CD1 . LEU B 1 345 ? 97.957  155.473 118.326 1.00 24.04  ? 345 LEU B CD1 1 
ATOM   6995  C CD2 . LEU B 1 345 ? 99.149  153.638 117.170 1.00 30.03  ? 345 LEU B CD2 1 
ATOM   6996  N N   . SER B 1 346 ? 94.417  151.841 115.048 1.00 30.17  ? 346 SER B N   1 
ATOM   6997  C CA  . SER B 1 346 ? 93.004  151.412 115.135 1.00 36.47  ? 346 SER B CA  1 
ATOM   6998  C C   . SER B 1 346 ? 92.679  150.311 116.160 1.00 43.13  ? 346 SER B C   1 
ATOM   6999  O O   . SER B 1 346 ? 91.784  150.488 116.988 1.00 46.70  ? 346 SER B O   1 
ATOM   7000  C CB  . SER B 1 346 ? 92.501  150.997 113.749 1.00 28.64  ? 346 SER B CB  1 
ATOM   7001  O OG  . SER B 1 346 ? 93.486  150.264 113.053 1.00 36.15  ? 346 SER B OG  1 
ATOM   7002  N N   . SER B 1 347 ? 93.411  149.198 116.144 1.00 28.09  ? 347 SER B N   1 
ATOM   7003  C CA  . SER B 1 347 ? 93.261  148.092 117.107 1.00 24.99  ? 347 SER B CA  1 
ATOM   7004  C C   . SER B 1 347 ? 94.419  147.981 118.112 1.00 28.30  ? 347 SER B C   1 
ATOM   7005  O O   . SER B 1 347 ? 94.562  146.983 118.817 1.00 27.09  ? 347 SER B O   1 
ATOM   7006  C CB  . SER B 1 347 ? 93.038  146.796 116.329 1.00 27.98  ? 347 SER B CB  1 
ATOM   7007  O OG  . SER B 1 347 ? 94.082  146.588 115.401 1.00 38.89  ? 347 SER B OG  1 
ATOM   7008  N N   . VAL B 1 348 ? 95.263  149.011 118.185 1.00 32.11  ? 348 VAL B N   1 
ATOM   7009  C CA  . VAL B 1 348 ? 96.500  149.051 118.967 1.00 26.66  ? 348 VAL B CA  1 
ATOM   7010  C C   . VAL B 1 348 ? 96.339  149.819 120.274 1.00 28.55  ? 348 VAL B C   1 
ATOM   7011  O O   . VAL B 1 348 ? 96.712  149.309 121.326 1.00 27.33  ? 348 VAL B O   1 
ATOM   7012  C CB  . VAL B 1 348 ? 97.668  149.590 118.123 1.00 29.12  ? 348 VAL B CB  1 
ATOM   7013  C CG1 . VAL B 1 348 ? 98.960  149.710 118.929 1.00 28.49  ? 348 VAL B CG1 1 
ATOM   7014  C CG2 . VAL B 1 348 ? 97.956  148.681 116.928 1.00 18.74  ? 348 VAL B CG2 1 
ATOM   7015  N N   . ASP B 1 349 ? 95.783  151.027 120.221 1.00 34.25  ? 349 ASP B N   1 
ATOM   7016  C CA  . ASP B 1 349 ? 95.653  151.905 121.385 1.00 35.97  ? 349 ASP B CA  1 
ATOM   7017  C C   . ASP B 1 349 ? 94.738  151.292 122.462 1.00 36.18  ? 349 ASP B C   1 
ATOM   7018  O O   . ASP B 1 349 ? 93.672  150.753 122.168 1.00 44.84  ? 349 ASP B O   1 
ATOM   7019  C CB  . ASP B 1 349 ? 95.168  153.284 120.920 1.00 34.90  ? 349 ASP B CB  1 
ATOM   7020  C CG  . ASP B 1 349 ? 95.137  154.355 122.019 1.00 44.47  ? 349 ASP B CG  1 
ATOM   7021  O OD1 . ASP B 1 349 ? 95.790  154.171 123.074 1.00 41.19  ? 349 ASP B OD1 1 
ATOM   7022  O OD2 . ASP B 1 349 ? 94.445  155.369 121.801 1.00 49.03  ? 349 ASP B OD2 1 
ATOM   7023  N N   . SER B 1 350 ? 95.147  151.391 123.723 1.00 33.59  ? 350 SER B N   1 
ATOM   7024  C CA  . SER B 1 350 ? 94.471  150.863 124.914 1.00 32.69  ? 350 SER B CA  1 
ATOM   7025  C C   . SER B 1 350 ? 93.181  151.597 125.306 1.00 36.35  ? 350 SER B C   1 
ATOM   7026  O O   . SER B 1 350 ? 92.504  151.189 126.250 1.00 39.80  ? 350 SER B O   1 
ATOM   7027  C CB  . SER B 1 350 ? 95.467  150.894 126.069 1.00 34.43  ? 350 SER B CB  1 
ATOM   7028  O OG  . SER B 1 350 ? 96.017  152.185 126.191 1.00 41.87  ? 350 SER B OG  1 
ATOM   7029  N N   . TRP B 1 351 ? 92.805  152.657 124.587 1.00 39.40  ? 351 TRP B N   1 
ATOM   7030  C CA  . TRP B 1 351 ? 91.482  153.277 124.671 1.00 39.52  ? 351 TRP B CA  1 
ATOM   7031  C C   . TRP B 1 351 ? 90.361  152.298 124.306 1.00 43.73  ? 351 TRP B C   1 
ATOM   7032  O O   . TRP B 1 351 ? 89.296  152.321 124.914 1.00 44.59  ? 351 TRP B O   1 
ATOM   7033  C CB  . TRP B 1 351 ? 91.466  154.497 123.747 1.00 41.65  ? 351 TRP B CB  1 
ATOM   7034  C CG  . TRP B 1 351 ? 90.139  155.158 123.559 1.00 46.52  ? 351 TRP B CG  1 
ATOM   7035  C CD1 . TRP B 1 351 ? 89.615  156.120 124.347 1.00 42.19  ? 351 TRP B CD1 1 
ATOM   7036  C CD2 . TRP B 1 351 ? 89.129  154.894 122.536 1.00 44.75  ? 351 TRP B CD2 1 
ATOM   7037  N NE1 . TRP B 1 351 ? 88.370  156.486 123.880 1.00 42.79  ? 351 TRP B NE1 1 
ATOM   7038  C CE2 . TRP B 1 351 ? 88.016  155.757 122.766 1.00 43.02  ? 351 TRP B CE2 1 
ATOM   7039  C CE3 . TRP B 1 351 ? 89.059  154.035 121.421 1.00 38.80  ? 351 TRP B CE3 1 
ATOM   7040  C CZ2 . TRP B 1 351 ? 86.881  155.749 121.947 1.00 42.38  ? 351 TRP B CZ2 1 
ATOM   7041  C CZ3 . TRP B 1 351 ? 87.919  154.009 120.601 1.00 43.16  ? 351 TRP B CZ3 1 
ATOM   7042  C CH2 . TRP B 1 351 ? 86.831  154.858 120.863 1.00 46.16  ? 351 TRP B CH2 1 
ATOM   7043  N N   . GLU B 1 352 ? 90.604  151.418 123.335 1.00 46.79  ? 352 GLU B N   1 
ATOM   7044  C CA  . GLU B 1 352 ? 89.672  150.371 122.918 1.00 41.40  ? 352 GLU B CA  1 
ATOM   7045  C C   . GLU B 1 352 ? 89.847  149.091 123.751 1.00 43.03  ? 352 GLU B C   1 
ATOM   7046  O O   . GLU B 1 352 ? 90.951  148.724 124.154 1.00 42.01  ? 352 GLU B O   1 
ATOM   7047  C CB  . GLU B 1 352 ? 89.863  150.130 121.409 1.00 45.07  ? 352 GLU B CB  1 
ATOM   7048  C CG  . GLU B 1 352 ? 88.952  149.098 120.741 1.00 46.36  ? 352 GLU B CG  1 
ATOM   7049  C CD  . GLU B 1 352 ? 87.452  149.396 120.891 1.00 53.21  ? 352 GLU B CD  1 
ATOM   7050  O OE1 . GLU B 1 352 ? 86.943  149.392 122.035 1.00 51.00  ? 352 GLU B OE1 1 
ATOM   7051  O OE2 . GLU B 1 352 ? 86.780  149.600 119.860 1.00 52.49  ? 352 GLU B OE2 1 
ATOM   7052  N N   . LYS B 1 353 ? 88.753  148.373 124.000 1.00 45.08  ? 353 LYS B N   1 
ATOM   7053  C CA  . LYS B 1 353 ? 88.767  147.085 124.704 1.00 46.63  ? 353 LYS B CA  1 
ATOM   7054  C C   . LYS B 1 353 ? 89.561  146.037 123.912 1.00 47.55  ? 353 LYS B C   1 
ATOM   7055  O O   . LYS B 1 353 ? 89.419  145.945 122.694 1.00 43.78  ? 353 LYS B O   1 
ATOM   7056  C CB  . LYS B 1 353 ? 87.313  146.641 124.934 1.00 46.56  ? 353 LYS B CB  1 
ATOM   7057  C CG  . LYS B 1 353 ? 87.193  145.376 125.786 1.00 49.58  ? 353 LYS B CG  1 
ATOM   7058  C CD  . LYS B 1 353 ? 85.744  144.930 125.933 1.00 49.77  ? 353 LYS B CD  1 
ATOM   7059  C CE  . LYS B 1 353 ? 85.651  143.612 126.685 1.00 51.18  ? 353 LYS B CE  1 
ATOM   7060  N NZ  . LYS B 1 353 ? 84.275  143.107 126.770 1.00 49.38  ? 353 LYS B NZ  1 
ATOM   7061  N N   . ASN B 1 354 ? 90.334  145.193 124.601 1.00 40.45  ? 354 ASN B N   1 
ATOM   7062  C CA  . ASN B 1 354 ? 91.033  144.045 124.010 1.00 34.00  ? 354 ASN B CA  1 
ATOM   7063  C C   . ASN B 1 354 ? 91.993  144.454 122.872 1.00 33.99  ? 354 ASN B C   1 
ATOM   7064  O O   . ASN B 1 354 ? 92.010  143.851 121.803 1.00 45.33  ? 354 ASN B O   1 
ATOM   7065  C CB  . ASN B 1 354 ? 89.988  142.972 123.632 1.00 39.77  ? 354 ASN B CB  1 
ATOM   7066  C CG  . ASN B 1 354 ? 90.590  141.628 123.262 1.00 46.37  ? 354 ASN B CG  1 
ATOM   7067  O OD1 . ASN B 1 354 ? 91.419  141.089 123.969 1.00 45.96  ? 354 ASN B OD1 1 
ATOM   7068  N ND2 . ASN B 1 354 ? 90.169  141.023 122.180 1.00 43.65  ? 354 ASN B ND2 1 
ATOM   7069  N N   . SER B 1 355 ? 92.739  145.542 123.057 1.00 29.65  ? 355 SER B N   1 
ATOM   7070  C CA  . SER B 1 355 ? 93.694  146.050 122.072 1.00 21.78  ? 355 SER B CA  1 
ATOM   7071  C C   . SER B 1 355 ? 94.981  145.228 122.045 1.00 19.27  ? 355 SER B C   1 
ATOM   7072  O O   . SER B 1 355 ? 95.244  144.426 122.937 1.00 28.48  ? 355 SER B O   1 
ATOM   7073  C CB  . SER B 1 355 ? 93.985  147.525 122.331 1.00 20.95  ? 355 SER B CB  1 
ATOM   7074  O OG  . SER B 1 355 ? 94.945  147.711 123.345 1.00 27.57  ? 355 SER B OG  1 
ATOM   7075  N N   . VAL B 1 356 ? 95.830  145.444 121.043 1.00 21.92  ? 356 VAL B N   1 
ATOM   7076  C CA  . VAL B 1 356 ? 97.154  144.800 120.961 1.00 18.73  ? 356 VAL B CA  1 
ATOM   7077  C C   . VAL B 1 356 ? 98.007  145.040 122.206 1.00 15.30  ? 356 VAL B C   1 
ATOM   7078  O O   . VAL B 1 356 ? 98.691  144.125 122.650 1.00 30.37  ? 356 VAL B O   1 
ATOM   7079  C CB  . VAL B 1 356 ? 97.865  145.258 119.681 1.00 25.48  ? 356 VAL B CB  1 
ATOM   7080  C CG1 . VAL B 1 356 ? 99.377  145.099 119.656 1.00 25.95  ? 356 VAL B CG1 1 
ATOM   7081  C CG2 . VAL B 1 356 ? 97.281  144.523 118.476 1.00 19.97  ? 356 VAL B CG2 1 
ATOM   7082  N N   . LEU B 1 357 ? 97.952  146.228 122.810 1.00 35.64  ? 357 LEU B N   1 
ATOM   7083  C CA  . LEU B 1 357 ? 98.680  146.516 124.046 1.00 19.10  ? 357 LEU B CA  1 
ATOM   7084  C C   . LEU B 1 357 ? 98.178  145.690 125.232 1.00 17.29  ? 357 LEU B C   1 
ATOM   7085  O O   . LEU B 1 357 ? 98.980  145.091 125.939 1.00 25.97  ? 357 LEU B O   1 
ATOM   7086  C CB  . LEU B 1 357 ? 98.577  148.012 124.359 1.00 22.65  ? 357 LEU B CB  1 
ATOM   7087  C CG  . LEU B 1 357 ? 99.361  148.939 123.421 1.00 23.00  ? 357 LEU B CG  1 
ATOM   7088  C CD1 . LEU B 1 357 ? 99.100  150.379 123.844 1.00 22.52  ? 357 LEU B CD1 1 
ATOM   7089  C CD2 . LEU B 1 357 ? 100.863 148.685 123.485 1.00 25.16  ? 357 LEU B CD2 1 
ATOM   7090  N N   . GLU B 1 358 ? 96.862  145.604 125.435 1.00 25.47  ? 358 GLU B N   1 
ATOM   7091  C CA  . GLU B 1 358 ? 96.269  144.754 126.469 1.00 20.32  ? 358 GLU B CA  1 
ATOM   7092  C C   . GLU B 1 358 ? 96.578  143.267 126.241 1.00 29.36  ? 358 GLU B C   1 
ATOM   7093  O O   . GLU B 1 358 ? 96.899  142.548 127.186 1.00 36.00  ? 358 GLU B O   1 
ATOM   7094  C CB  . GLU B 1 358 ? 94.759  145.034 126.554 1.00 26.23  ? 358 GLU B CB  1 
ATOM   7095  C CG  . GLU B 1 358 ? 94.077  144.147 127.602 1.00 35.82  ? 358 GLU B CG  1 
ATOM   7096  C CD  . GLU B 1 358 ? 92.744  144.696 128.126 1.00 45.71  ? 358 GLU B CD  1 
ATOM   7097  O OE1 . GLU B 1 358 ? 91.866  145.054 127.309 1.00 46.33  ? 358 GLU B OE1 1 
ATOM   7098  O OE2 . GLU B 1 358 ? 92.574  144.737 129.367 1.00 41.00  ? 358 GLU B OE2 1 
ATOM   7099  N N   . ILE B 1 359 ? 96.565  142.806 124.991 1.00 25.01  ? 359 ILE B N   1 
ATOM   7100  C CA  . ILE B 1 359 ? 96.919  141.435 124.628 1.00 24.21  ? 359 ILE B CA  1 
ATOM   7101  C C   . ILE B 1 359 ? 98.389  141.131 124.911 1.00 23.34  ? 359 ILE B C   1 
ATOM   7102  O O   . ILE B 1 359 ? 98.670  140.121 125.544 1.00 35.36  ? 359 ILE B O   1 
ATOM   7103  C CB  . ILE B 1 359 ? 96.533  141.136 123.168 1.00 23.54  ? 359 ILE B CB  1 
ATOM   7104  C CG1 . ILE B 1 359 ? 94.999  141.065 123.052 1.00 18.08  ? 359 ILE B CG1 1 
ATOM   7105  C CG2 . ILE B 1 359 ? 97.155  139.828 122.662 1.00 22.39  ? 359 ILE B CG2 1 
ATOM   7106  C CD1 . ILE B 1 359 ? 94.500  141.196 121.625 1.00 22.31  ? 359 ILE B CD1 1 
ATOM   7107  N N   . ILE B 1 360 ? 99.350  141.962 124.499 1.00 26.23  ? 360 ILE B N   1 
ATOM   7108  C CA  . ILE B 1 360 ? 100.773 141.709 124.782 1.00 23.61  ? 360 ILE B CA  1 
ATOM   7109  C C   . ILE B 1 360 ? 101.045 141.693 126.290 1.00 26.51  ? 360 ILE B C   1 
ATOM   7110  O O   . ILE B 1 360 ? 101.750 140.814 126.784 1.00 34.65  ? 360 ILE B O   1 
ATOM   7111  C CB  . ILE B 1 360 ? 101.686 142.728 124.068 1.00 28.36  ? 360 ILE B CB  1 
ATOM   7112  C CG1 . ILE B 1 360 ? 101.605 142.565 122.542 1.00 21.88  ? 360 ILE B CG1 1 
ATOM   7113  C CG2 . ILE B 1 360 ? 103.151 142.562 124.512 1.00 21.69  ? 360 ILE B CG2 1 
ATOM   7114  C CD1 . ILE B 1 360 ? 102.120 143.782 121.772 1.00 22.19  ? 360 ILE B CD1 1 
ATOM   7115  N N   . ALA B 1 361 ? 100.470 142.635 127.037 1.00 27.43  ? 361 ALA B N   1 
ATOM   7116  C CA  . ALA B 1 361 ? 100.687 142.737 128.469 1.00 15.71  ? 361 ALA B CA  1 
ATOM   7117  C C   . ALA B 1 361 ? 100.083 141.557 129.252 1.00 23.10  ? 361 ALA B C   1 
ATOM   7118  O O   . ALA B 1 361 ? 100.779 140.988 130.089 1.00 29.44  ? 361 ALA B O   1 
ATOM   7119  C CB  . ALA B 1 361 ? 100.148 144.085 128.932 1.00 19.33  ? 361 ALA B CB  1 
ATOM   7120  N N   . PHE B 1 362 ? 98.833  141.167 128.978 1.00 26.02  ? 362 PHE B N   1 
ATOM   7121  C CA  . PHE B 1 362 ? 98.068  140.285 129.866 1.00 15.26  ? 362 PHE B CA  1 
ATOM   7122  C C   . PHE B 1 362 ? 97.562  138.973 129.263 1.00 25.99  ? 362 PHE B C   1 
ATOM   7123  O O   . PHE B 1 362 ? 97.264  138.061 130.030 1.00 39.19  ? 362 PHE B O   1 
ATOM   7124  C CB  . PHE B 1 362 ? 96.891  141.074 130.453 1.00 20.23  ? 362 PHE B CB  1 
ATOM   7125  C CG  . PHE B 1 362 ? 97.295  142.349 131.158 1.00 25.61  ? 362 PHE B CG  1 
ATOM   7126  C CD1 . PHE B 1 362 ? 98.001  142.295 132.371 1.00 24.75  ? 362 PHE B CD1 1 
ATOM   7127  C CD2 . PHE B 1 362 ? 97.017  143.594 130.572 1.00 29.32  ? 362 PHE B CD2 1 
ATOM   7128  C CE1 . PHE B 1 362 ? 98.424  143.480 132.991 1.00 25.99  ? 362 PHE B CE1 1 
ATOM   7129  C CE2 . PHE B 1 362 ? 97.440  144.779 131.191 1.00 23.42  ? 362 PHE B CE2 1 
ATOM   7130  C CZ  . PHE B 1 362 ? 98.151  144.722 132.398 1.00 27.02  ? 362 PHE B CZ  1 
ATOM   7131  N N   . HIS B 1 363 ? 97.414  138.840 127.941 1.00 26.53  ? 363 HIS B N   1 
ATOM   7132  C CA  . HIS B 1 363 ? 96.835  137.635 127.320 1.00 26.29  ? 363 HIS B CA  1 
ATOM   7133  C C   . HIS B 1 363 ? 97.882  136.770 126.618 1.00 30.54  ? 363 HIS B C   1 
ATOM   7134  O O   . HIS B 1 363 ? 97.708  135.566 126.483 1.00 38.18  ? 363 HIS B O   1 
ATOM   7135  C CB  . HIS B 1 363 ? 95.737  138.016 126.329 1.00 22.45  ? 363 HIS B CB  1 
ATOM   7136  C CG  . HIS B 1 363 ? 94.623  138.884 126.851 1.00 25.72  ? 363 HIS B CG  1 
ATOM   7137  N ND1 . HIS B 1 363 ? 93.655  139.471 126.040 1.00 40.84  ? 363 HIS B ND1 1 
ATOM   7138  C CD2 . HIS B 1 363 ? 94.343  139.202 128.145 1.00 30.29  ? 363 HIS B CD2 1 
ATOM   7139  C CE1 . HIS B 1 363 ? 92.841  140.152 126.857 1.00 36.77  ? 363 HIS B CE1 1 
ATOM   7140  N NE2 . HIS B 1 363 ? 93.233  140.006 128.126 1.00 36.73  ? 363 HIS B NE2 1 
ATOM   7141  N N   . CYS B 1 364 ? 98.969  137.372 126.162 1.00 29.79  ? 364 CYS B N   1 
ATOM   7142  C CA  . CYS B 1 364 ? 100.107 136.675 125.595 1.00 26.62  ? 364 CYS B CA  1 
ATOM   7143  C C   . CYS B 1 364 ? 100.904 135.962 126.703 1.00 34.81  ? 364 CYS B C   1 
ATOM   7144  O O   . CYS B 1 364 ? 101.099 136.514 127.783 1.00 32.33  ? 364 CYS B O   1 
ATOM   7145  C CB  . CYS B 1 364 ? 100.938 137.699 124.817 1.00 24.75  ? 364 CYS B CB  1 
ATOM   7146  S SG  . CYS B 1 364 ? 102.286 136.878 123.951 1.00 25.19  ? 364 CYS B SG  1 
ATOM   7147  N N   . LYS B 1 365 ? 101.408 134.758 126.422 1.00 41.48  ? 365 LYS B N   1 
ATOM   7148  C CA  . LYS B 1 365 ? 102.301 133.987 127.307 1.00 35.42  ? 365 LYS B CA  1 
ATOM   7149  C C   . LYS B 1 365 ? 103.608 133.540 126.651 1.00 34.83  ? 365 LYS B C   1 
ATOM   7150  O O   . LYS B 1 365 ? 104.306 132.671 127.163 1.00 44.31  ? 365 LYS B O   1 
ATOM   7151  C CB  . LYS B 1 365 ? 101.517 132.868 128.006 1.00 41.38  ? 365 LYS B CB  1 
ATOM   7152  C CG  . LYS B 1 365 ? 100.965 131.792 127.069 1.00 41.92  ? 365 LYS B CG  1 
ATOM   7153  C CD  . LYS B 1 365 ? 100.179 130.751 127.869 1.00 42.97  ? 365 LYS B CD  1 
ATOM   7154  C CE  . LYS B 1 365 ? 99.649  129.650 126.953 1.00 44.51  ? 365 LYS B CE  1 
ATOM   7155  N NZ  . LYS B 1 365 ? 98.920  128.615 127.719 1.00 43.68  ? 365 LYS B NZ  1 
ATOM   7156  N N   . SER B 1 366 ? 103.948 134.145 125.520 1.00 34.77  ? 366 SER B N   1 
ATOM   7157  C CA  . SER B 1 366 ? 105.206 133.930 124.804 1.00 33.52  ? 366 SER B CA  1 
ATOM   7158  C C   . SER B 1 366 ? 106.394 134.593 125.520 1.00 28.32  ? 366 SER B C   1 
ATOM   7159  O O   . SER B 1 366 ? 106.226 135.676 126.081 1.00 35.10  ? 366 SER B O   1 
ATOM   7160  C CB  . SER B 1 366 ? 105.049 134.491 123.390 1.00 32.52  ? 366 SER B CB  1 
ATOM   7161  O OG  . SER B 1 366 ? 106.212 134.292 122.626 1.00 33.45  ? 366 SER B OG  1 
ATOM   7162  N N   . PRO B 1 367 ? 107.619 134.040 125.474 1.00 37.32  ? 367 PRO B N   1 
ATOM   7163  C CA  . PRO B 1 367 ? 108.800 134.671 126.072 1.00 37.80  ? 367 PRO B CA  1 
ATOM   7164  C C   . PRO B 1 367 ? 109.254 135.966 125.379 1.00 40.74  ? 367 PRO B C   1 
ATOM   7165  O O   . PRO B 1 367 ? 110.058 136.709 125.932 1.00 48.45  ? 367 PRO B O   1 
ATOM   7166  C CB  . PRO B 1 367 ? 109.888 133.599 126.020 1.00 41.59  ? 367 PRO B CB  1 
ATOM   7167  C CG  . PRO B 1 367 ? 109.483 132.723 124.842 1.00 38.19  ? 367 PRO B CG  1 
ATOM   7168  C CD  . PRO B 1 367 ? 107.963 132.735 124.930 1.00 39.45  ? 367 PRO B CD  1 
ATOM   7169  N N   . ASN B 1 368 ? 108.771 136.241 124.164 1.00 34.15  ? 368 ASN B N   1 
ATOM   7170  C CA  . ASN B 1 368 ? 109.156 137.406 123.360 1.00 34.84  ? 368 ASN B CA  1 
ATOM   7171  C C   . ASN B 1 368 ? 108.211 138.616 123.487 1.00 36.18  ? 368 ASN B C   1 
ATOM   7172  O O   . ASN B 1 368 ? 108.321 139.559 122.704 1.00 44.69  ? 368 ASN B O   1 
ATOM   7173  C CB  . ASN B 1 368 ? 109.417 136.970 121.903 1.00 39.74  ? 368 ASN B CB  1 
ATOM   7174  C CG  . ASN B 1 368 ? 108.198 136.470 121.163 1.00 38.85  ? 368 ASN B CG  1 
ATOM   7175  O OD1 . ASN B 1 368 ? 107.066 136.583 121.605 1.00 46.06  ? 368 ASN B OD1 1 
ATOM   7176  N ND2 . ASN B 1 368 ? 108.381 135.855 120.028 1.00 33.67  ? 368 ASN B ND2 1 
ATOM   7177  N N   . ARG B 1 369 ? 107.328 138.659 124.494 1.00 27.25  ? 369 ARG B N   1 
ATOM   7178  C CA  . ARG B 1 369 ? 106.480 139.829 124.807 1.00 29.07  ? 369 ARG B CA  1 
ATOM   7179  C C   . ARG B 1 369 ? 107.275 141.121 124.931 1.00 28.00  ? 369 ARG B C   1 
ATOM   7180  O O   . ARG B 1 369 ? 106.857 142.164 124.441 1.00 29.83  ? 369 ARG B O   1 
ATOM   7181  C CB  . ARG B 1 369 ? 105.718 139.581 126.117 1.00 28.58  ? 369 ARG B CB  1 
ATOM   7182  C CG  . ARG B 1 369 ? 104.526 138.657 125.904 1.00 28.78  ? 369 ARG B CG  1 
ATOM   7183  C CD  . ARG B 1 369 ? 104.040 138.028 127.206 1.00 33.15  ? 369 ARG B CD  1 
ATOM   7184  N NE  . ARG B 1 369 ? 103.569 139.014 128.197 1.00 33.56  ? 369 ARG B NE  1 
ATOM   7185  C CZ  . ARG B 1 369 ? 104.084 139.243 129.390 1.00 29.11  ? 369 ARG B CZ  1 
ATOM   7186  N NH1 . ARG B 1 369 ? 103.515 140.022 130.251 1.00 21.79  ? 369 ARG B NH1 1 
ATOM   7187  N NH2 . ARG B 1 369 ? 105.202 138.709 129.774 1.00 31.11  ? 369 ARG B NH2 1 
ATOM   7188  N N   . HIS B 1 370 ? 108.455 141.061 125.543 1.00 31.40  ? 370 HIS B N   1 
ATOM   7189  C CA  . HIS B 1 370 ? 109.307 142.230 125.738 1.00 28.29  ? 370 HIS B CA  1 
ATOM   7190  C C   . HIS B 1 370 ? 109.936 142.748 124.438 1.00 28.19  ? 370 HIS B C   1 
ATOM   7191  O O   . HIS B 1 370 ? 110.252 143.953 124.393 1.00 36.87  ? 370 HIS B O   1 
ATOM   7192  C CB  . HIS B 1 370 ? 110.403 141.908 126.764 1.00 27.88  ? 370 HIS B CB  1 
ATOM   7193  C CG  . HIS B 1 370 ? 111.402 140.912 126.278 1.00 28.58  ? 370 HIS B CG  1 
ATOM   7194  N ND1 . HIS B 1 370 ? 112.629 141.288 125.769 1.00 27.18  ? 370 HIS B ND1 1 
ATOM   7195  C CD2 . HIS B 1 370 ? 111.361 139.564 126.214 1.00 32.07  ? 370 HIS B CD2 1 
ATOM   7196  C CE1 . HIS B 1 370 ? 113.304 140.213 125.416 1.00 33.53  ? 370 HIS B CE1 1 
ATOM   7197  N NE2 . HIS B 1 370 ? 112.547 139.140 125.679 1.00 36.00  ? 370 HIS B NE2 1 
ATOM   7198  N N   . ARG B 1 371 ? 110.109 141.894 123.423 1.00 31.10  ? 371 ARG B N   1 
ATOM   7199  C CA  . ARG B 1 371 ? 110.532 142.304 122.079 1.00 29.03  ? 371 ARG B CA  1 
ATOM   7200  C C   . ARG B 1 371 ? 109.404 142.975 121.287 1.00 31.75  ? 371 ARG B C   1 
ATOM   7201  O O   . ARG B 1 371 ? 109.679 143.879 120.512 1.00 28.95  ? 371 ARG B O   1 
ATOM   7202  C CB  . ARG B 1 371 ? 111.107 141.092 121.330 1.00 28.97  ? 371 ARG B CB  1 
ATOM   7203  C CG  . ARG B 1 371 ? 112.478 140.649 121.844 1.00 27.08  ? 371 ARG B CG  1 
ATOM   7204  C CD  . ARG B 1 371 ? 112.895 139.239 121.394 1.00 38.21  ? 371 ARG B CD  1 
ATOM   7205  N NE  . ARG B 1 371 ? 112.647 138.913 119.968 1.00 38.63  ? 371 ARG B NE  1 
ATOM   7206  C CZ  . ARG B 1 371 ? 113.236 139.410 118.895 1.00 38.70  ? 371 ARG B CZ  1 
ATOM   7207  N NH1 . ARG B 1 371 ? 112.993 138.912 117.723 1.00 36.80  ? 371 ARG B NH1 1 
ATOM   7208  N NH2 . ARG B 1 371 ? 114.076 140.397 118.952 1.00 37.65  ? 371 ARG B NH2 1 
ATOM   7209  N N   . MET B 1 372 ? 108.143 142.593 121.495 1.00 30.92  ? 372 MET B N   1 
ATOM   7210  C CA  . MET B 1 372 ? 106.993 143.222 120.834 1.00 20.81  ? 372 MET B CA  1 
ATOM   7211  C C   . MET B 1 372 ? 106.689 144.646 121.315 1.00 29.09  ? 372 MET B C   1 
ATOM   7212  O O   . MET B 1 372 ? 106.339 145.491 120.498 1.00 40.22  ? 372 MET B O   1 
ATOM   7213  C CB  . MET B 1 372 ? 105.739 142.355 120.968 1.00 20.21  ? 372 MET B CB  1 
ATOM   7214  C CG  . MET B 1 372 ? 105.844 141.078 120.139 1.00 34.13  ? 372 MET B CG  1 
ATOM   7215  S SD  . MET B 1 372 ? 104.312 140.136 119.985 1.00 47.10  ? 372 MET B SD  1 
ATOM   7216  C CE  . MET B 1 372 ? 104.188 139.468 121.660 1.00 27.45  ? 372 MET B CE  1 
ATOM   7217  N N   . VAL B 1 373 ? 106.834 144.960 122.607 1.00 27.91  ? 373 VAL B N   1 
ATOM   7218  C CA  . VAL B 1 373 ? 106.519 146.306 123.136 1.00 24.47  ? 373 VAL B CA  1 
ATOM   7219  C C   . VAL B 1 373 ? 107.518 147.390 122.720 1.00 27.27  ? 373 VAL B C   1 
ATOM   7220  O O   . VAL B 1 373 ? 107.216 148.570 122.850 1.00 33.42  ? 373 VAL B O   1 
ATOM   7221  C CB  . VAL B 1 373 ? 106.342 146.336 124.668 1.00 31.43  ? 373 VAL B CB  1 
ATOM   7222  C CG1 . VAL B 1 373 ? 105.199 145.441 125.121 1.00 27.63  ? 373 VAL B CG1 1 
ATOM   7223  C CG2 . VAL B 1 373 ? 107.606 145.966 125.433 1.00 19.54  ? 373 VAL B CG2 1 
ATOM   7224  N N   . VAL B 1 374 ? 108.694 147.013 122.215 1.00 21.51  ? 374 VAL B N   1 
ATOM   7225  C CA  . VAL B 1 374 ? 109.745 147.946 121.778 1.00 18.12  ? 374 VAL B CA  1 
ATOM   7226  C C   . VAL B 1 374 ? 109.772 148.176 120.260 1.00 23.25  ? 374 VAL B C   1 
ATOM   7227  O O   . VAL B 1 374 ? 110.670 148.844 119.758 1.00 31.19  ? 374 VAL B O   1 
ATOM   7228  C CB  . VAL B 1 374 ? 111.127 147.578 122.360 1.00 23.21  ? 374 VAL B CB  1 
ATOM   7229  C CG1 . VAL B 1 374 ? 111.102 147.564 123.889 1.00 29.00  ? 374 VAL B CG1 1 
ATOM   7230  C CG2 . VAL B 1 374 ? 111.653 146.234 121.872 1.00 23.29  ? 374 VAL B CG2 1 
ATOM   7231  N N   . LEU B 1 375 ? 108.789 147.662 119.515 1.00 25.16  ? 375 LEU B N   1 
ATOM   7232  C CA  . LEU B 1 375 ? 108.593 147.954 118.090 1.00 26.60  ? 375 LEU B CA  1 
ATOM   7233  C C   . LEU B 1 375 ? 107.920 149.320 117.888 1.00 27.96  ? 375 LEU B C   1 
ATOM   7234  O O   . LEU B 1 375 ? 107.105 149.723 118.706 1.00 30.74  ? 375 LEU B O   1 
ATOM   7235  C CB  . LEU B 1 375 ? 107.733 146.842 117.464 1.00 28.46  ? 375 LEU B CB  1 
ATOM   7236  C CG  . LEU B 1 375 ? 108.297 145.422 117.596 1.00 23.47  ? 375 LEU B CG  1 
ATOM   7237  C CD1 . LEU B 1 375 ? 107.343 144.434 116.952 1.00 23.02  ? 375 LEU B CD1 1 
ATOM   7238  C CD2 . LEU B 1 375 ? 109.662 145.274 116.941 1.00 26.31  ? 375 LEU B CD2 1 
ATOM   7239  N N   . GLU B 1 376 ? 108.165 150.027 116.784 1.00 31.53  ? 376 GLU B N   1 
ATOM   7240  C CA  . GLU B 1 376 ? 107.280 151.131 116.372 1.00 32.11  ? 376 GLU B CA  1 
ATOM   7241  C C   . GLU B 1 376 ? 105.920 150.594 115.889 1.00 26.50  ? 376 GLU B C   1 
ATOM   7242  O O   . GLU B 1 376 ? 105.896 149.555 115.226 1.00 34.91  ? 376 GLU B O   1 
ATOM   7243  C CB  . GLU B 1 376 ? 107.908 151.982 115.261 1.00 32.34  ? 376 GLU B CB  1 
ATOM   7244  C CG  . GLU B 1 376 ? 109.126 152.787 115.718 1.00 34.25  ? 376 GLU B CG  1 
ATOM   7245  C CD  . GLU B 1 376 ? 109.804 153.581 114.575 1.00 46.17  ? 376 GLU B CD  1 
ATOM   7246  O OE1 . GLU B 1 376 ? 109.190 153.776 113.499 1.00 44.27  ? 376 GLU B OE1 1 
ATOM   7247  O OE2 . GLU B 1 376 ? 110.962 154.008 114.773 1.00 46.32  ? 376 GLU B OE2 1 
ATOM   7248  N N   . PRO B 1 377 ? 104.791 151.282 116.156 1.00 22.39  ? 377 PRO B N   1 
ATOM   7249  C CA  . PRO B 1 377 ? 104.663 152.518 116.931 1.00 21.06  ? 377 PRO B CA  1 
ATOM   7250  C C   . PRO B 1 377 ? 104.477 152.268 118.442 1.00 24.64  ? 377 PRO B C   1 
ATOM   7251  O O   . PRO B 1 377 ? 104.271 153.241 119.144 1.00 28.92  ? 377 PRO B O   1 
ATOM   7252  C CB  . PRO B 1 377 ? 103.351 153.129 116.442 1.00 21.74  ? 377 PRO B CB  1 
ATOM   7253  C CG  . PRO B 1 377 ? 102.488 151.903 116.173 1.00 27.01  ? 377 PRO B CG  1 
ATOM   7254  C CD  . PRO B 1 377 ? 103.494 150.900 115.620 1.00 15.73  ? 377 PRO B CD  1 
ATOM   7255  N N   . LEU B 1 378 ? 104.558 151.014 118.915 1.00 30.89  ? 378 LEU B N   1 
ATOM   7256  C CA  . LEU B 1 378 ? 104.278 150.673 120.350 1.00 23.66  ? 378 LEU B CA  1 
ATOM   7257  C C   . LEU B 1 378 ? 105.299 151.315 121.300 1.00 28.91  ? 378 LEU B C   1 
ATOM   7258  O O   . LEU B 1 378 ? 104.902 151.818 122.342 1.00 35.48  ? 378 LEU B O   1 
ATOM   7259  C CB  . LEU B 1 378 ? 104.287 149.148 120.506 1.00 26.44  ? 378 LEU B CB  1 
ATOM   7260  C CG  . LEU B 1 378 ? 102.997 148.431 120.110 1.00 29.37  ? 378 LEU B CG  1 
ATOM   7261  C CD1 . LEU B 1 378 ? 102.658 148.677 118.648 1.00 26.46  ? 378 LEU B CD1 1 
ATOM   7262  C CD2 . LEU B 1 378 ? 103.104 146.938 120.385 1.00 29.92  ? 378 LEU B CD2 1 
ATOM   7263  N N   . ASN B 1 379 ? 106.577 151.368 120.940 1.00 27.56  ? 379 ASN B N   1 
ATOM   7264  C CA  . ASN B 1 379 ? 107.634 151.975 121.736 1.00 13.97  ? 379 ASN B CA  1 
ATOM   7265  C C   . ASN B 1 379 ? 107.349 153.448 122.080 1.00 19.97  ? 379 ASN B C   1 
ATOM   7266  O O   . ASN B 1 379 ? 107.278 153.808 123.250 1.00 36.01  ? 379 ASN B O   1 
ATOM   7267  C CB  . ASN B 1 379 ? 108.951 151.807 120.970 1.00 20.00  ? 379 ASN B CB  1 
ATOM   7268  C CG  . ASN B 1 379 ? 110.161 152.224 121.783 1.00 33.20  ? 379 ASN B CG  1 
ATOM   7269  O OD1 . ASN B 1 379 ? 110.393 151.754 122.881 1.00 36.70  ? 379 ASN B OD1 1 
ATOM   7270  N ND2 . ASN B 1 379 ? 110.966 153.119 121.279 1.00 30.42  ? 379 ASN B ND2 1 
ATOM   7271  N N   . LYS B 1 380 ? 107.148 154.309 121.074 1.00 32.46  ? 380 LYS B N   1 
ATOM   7272  C CA  . LYS B 1 380 ? 106.868 155.735 121.286 1.00 24.60  ? 380 LYS B CA  1 
ATOM   7273  C C   . LYS B 1 380 ? 105.475 155.949 121.875 1.00 22.87  ? 380 LYS B C   1 
ATOM   7274  O O   . LYS B 1 380 ? 105.302 156.830 122.707 1.00 33.77  ? 380 LYS B O   1 
ATOM   7275  C CB  . LYS B 1 380 ? 107.106 156.538 119.989 1.00 27.43  ? 380 LYS B CB  1 
ATOM   7276  C CG  . LYS B 1 380 ? 106.956 158.053 120.247 1.00 36.01  ? 380 LYS B CG  1 
ATOM   7277  C CD  . LYS B 1 380 ? 106.864 158.935 119.001 1.00 32.56  ? 380 LYS B CD  1 
ATOM   7278  C CE  . LYS B 1 380 ? 106.502 160.357 119.459 1.00 35.04  ? 380 LYS B CE  1 
ATOM   7279  N NZ  . LYS B 1 380 ? 106.293 161.289 118.325 1.00 34.60  ? 380 LYS B NZ  1 
ATOM   7280  N N   . LEU B 1 381 ? 104.495 155.131 121.508 1.00 16.57  ? 381 LEU B N   1 
ATOM   7281  C CA  . LEU B 1 381 ? 103.148 155.191 122.071 1.00 19.42  ? 381 LEU B CA  1 
ATOM   7282  C C   . LEU B 1 381 ? 103.142 154.887 123.575 1.00 23.99  ? 381 LEU B C   1 
ATOM   7283  O O   . LEU B 1 381 ? 102.540 155.606 124.362 1.00 35.47  ? 381 LEU B O   1 
ATOM   7284  C CB  . LEU B 1 381 ? 102.268 154.216 121.273 1.00 25.64  ? 381 LEU B CB  1 
ATOM   7285  C CG  . LEU B 1 381 ? 100.804 154.159 121.718 1.00 30.04  ? 381 LEU B CG  1 
ATOM   7286  C CD1 . LEU B 1 381 ? 100.095 155.475 121.452 1.00 28.72  ? 381 LEU B CD1 1 
ATOM   7287  C CD2 . LEU B 1 381 ? 100.094 153.052 120.950 1.00 27.08  ? 381 LEU B CD2 1 
ATOM   7288  N N   . LEU B 1 382 ? 103.856 153.851 124.006 1.00 30.48  ? 382 LEU B N   1 
ATOM   7289  C CA  . LEU B 1 382 ? 104.021 153.518 125.417 1.00 18.83  ? 382 LEU B CA  1 
ATOM   7290  C C   . LEU B 1 382 ? 104.858 154.552 126.161 1.00 20.21  ? 382 LEU B C   1 
ATOM   7291  O O   . LEU B 1 382 ? 104.542 154.846 127.307 1.00 35.02  ? 382 LEU B O   1 
ATOM   7292  C CB  . LEU B 1 382 ? 104.615 152.112 125.552 1.00 20.59  ? 382 LEU B CB  1 
ATOM   7293  C CG  . LEU B 1 382 ? 103.601 150.997 125.254 1.00 19.70  ? 382 LEU B CG  1 
ATOM   7294  C CD1 . LEU B 1 382 ? 104.338 149.678 125.092 1.00 16.69  ? 382 LEU B CD1 1 
ATOM   7295  C CD2 . LEU B 1 382 ? 102.570 150.858 126.374 1.00 22.15  ? 382 LEU B CD2 1 
ATOM   7296  N N   . GLN B 1 383 ? 105.812 155.187 125.477 1.00 23.11  ? 383 GLN B N   1 
ATOM   7297  C CA  . GLN B 1 383 ? 106.575 156.285 126.132 1.00 16.96  ? 383 GLN B CA  1 
ATOM   7298  C C   . GLN B 1 383 ? 105.628 157.481 126.338 1.00 18.80  ? 383 GLN B C   1 
ATOM   7299  O O   . GLN B 1 383 ? 105.633 158.032 127.457 1.00 36.27  ? 383 GLN B O   1 
ATOM   7300  C CB  . GLN B 1 383 ? 107.852 156.584 125.336 1.00 20.50  ? 383 GLN B CB  1 
ATOM   7301  C CG  . GLN B 1 383 ? 108.805 157.539 126.067 1.00 27.15  ? 383 GLN B CG  1 
ATOM   7302  C CD  . GLN B 1 383 ? 109.206 157.017 127.424 1.00 34.10  ? 383 GLN B CD  1 
ATOM   7303  O OE1 . GLN B 1 383 ? 109.182 155.816 127.683 1.00 37.34  ? 383 GLN B OE1 1 
ATOM   7304  N NE2 . GLN B 1 383 ? 109.589 157.925 128.307 1.00 27.25  ? 383 GLN B NE2 1 
ATOM   7305  N N   . GLU B 1 384 ? 104.842 157.868 125.322 1.00 29.60  ? 384 GLU B N   1 
ATOM   7306  C CA  . GLU B 1 384 ? 103.843 158.927 125.467 1.00 29.50  ? 384 GLU B CA  1 
ATOM   7307  C C   . GLU B 1 384 ? 102.854 158.663 126.607 1.00 28.08  ? 384 GLU B C   1 
ATOM   7308  O O   . GLU B 1 384 ? 102.515 159.583 127.350 1.00 34.91  ? 384 GLU B O   1 
ATOM   7309  C CB  . GLU B 1 384 ? 103.074 159.084 124.144 1.00 32.49  ? 384 GLU B CB  1 
ATOM   7310  C CG  . GLU B 1 384 ? 103.820 159.955 123.125 1.00 33.51  ? 384 GLU B CG  1 
ATOM   7311  C CD  . GLU B 1 384 ? 103.702 161.459 123.395 1.00 44.15  ? 384 GLU B CD  1 
ATOM   7312  O OE1 . GLU B 1 384 ? 103.038 161.870 124.375 1.00 46.48  ? 384 GLU B OE1 1 
ATOM   7313  O OE2 . GLU B 1 384 ? 104.263 162.243 122.599 1.00 43.34  ? 384 GLU B OE2 1 
ATOM   7314  N N   . LYS B 1 385 ? 102.401 157.417 126.780 1.00 30.69  ? 385 LYS B N   1 
ATOM   7315  C CA  . LYS B 1 385 ? 101.556 157.017 127.907 1.00 22.34  ? 385 LYS B CA  1 
ATOM   7316  C C   . LYS B 1 385 ? 102.307 157.075 129.235 1.00 24.81  ? 385 LYS B C   1 
ATOM   7317  O O   . LYS B 1 385 ? 101.760 157.573 130.211 1.00 26.52  ? 385 LYS B O   1 
ATOM   7318  C CB  . LYS B 1 385 ? 100.993 155.616 127.668 1.00 24.31  ? 385 LYS B CB  1 
ATOM   7319  C CG  . LYS B 1 385 ? 99.936  155.563 126.565 1.00 22.06  ? 385 LYS B CG  1 
ATOM   7320  C CD  . LYS B 1 385 ? 99.517  154.126 126.247 1.00 23.09  ? 385 LYS B CD  1 
ATOM   7321  C CE  . LYS B 1 385 ? 98.522  154.055 125.089 1.00 25.88  ? 385 LYS B CE  1 
ATOM   7322  N NZ  . LYS B 1 385 ? 97.247  154.719 125.398 1.00 28.25  ? 385 LYS B NZ  1 
ATOM   7323  N N   . TRP B 1 386 ? 103.555 156.614 129.290 1.00 20.72  ? 386 TRP B N   1 
ATOM   7324  C CA  . TRP B 1 386 ? 104.388 156.714 130.490 1.00 13.26  ? 386 TRP B CA  1 
ATOM   7325  C C   . TRP B 1 386 ? 104.626 158.166 130.905 1.00 25.03  ? 386 TRP B C   1 
ATOM   7326  O O   . TRP B 1 386 ? 104.405 158.512 132.059 1.00 38.22  ? 386 TRP B O   1 
ATOM   7327  C CB  . TRP B 1 386 ? 105.727 155.991 130.306 1.00 23.45  ? 386 TRP B CB  1 
ATOM   7328  C CG  . TRP B 1 386 ? 106.606 156.081 131.520 1.00 22.59  ? 386 TRP B CG  1 
ATOM   7329  C CD1 . TRP B 1 386 ? 107.529 157.039 131.745 1.00 26.97  ? 386 TRP B CD1 1 
ATOM   7330  C CD2 . TRP B 1 386 ? 106.522 155.326 132.766 1.00 28.25  ? 386 TRP B CD2 1 
ATOM   7331  N NE1 . TRP B 1 386 ? 107.980 156.957 133.044 1.00 31.92  ? 386 TRP B NE1 1 
ATOM   7332  C CE2 . TRP B 1 386 ? 107.375 155.927 133.728 1.00 27.81  ? 386 TRP B CE2 1 
ATOM   7333  C CE3 . TRP B 1 386 ? 105.782 154.205 133.189 1.00 26.85  ? 386 TRP B CE3 1 
ATOM   7334  C CZ2 . TRP B 1 386 ? 107.480 155.452 135.044 1.00 23.15  ? 386 TRP B CZ2 1 
ATOM   7335  C CZ3 . TRP B 1 386 ? 105.861 153.725 134.506 1.00 19.05  ? 386 TRP B CZ3 1 
ATOM   7336  C CH2 . TRP B 1 386 ? 106.714 154.343 135.433 1.00 26.45  ? 386 TRP B CH2 1 
ATOM   7337  N N   . ASP B 1 387 ? 105.019 159.042 129.989 1.00 29.94  ? 387 ASP B N   1 
ATOM   7338  C CA  . ASP B 1 387 ? 105.329 160.438 130.293 1.00 26.01  ? 387 ASP B CA  1 
ATOM   7339  C C   . ASP B 1 387 ? 104.136 161.214 130.877 1.00 28.46  ? 387 ASP B C   1 
ATOM   7340  O O   . ASP B 1 387 ? 104.333 162.088 131.711 1.00 38.32  ? 387 ASP B O   1 
ATOM   7341  C CB  . ASP B 1 387 ? 105.857 161.145 129.038 1.00 28.09  ? 387 ASP B CB  1 
ATOM   7342  C CG  . ASP B 1 387 ? 107.235 160.674 128.553 1.00 35.08  ? 387 ASP B CG  1 
ATOM   7343  O OD1 . ASP B 1 387 ? 107.938 159.937 129.277 1.00 37.03  ? 387 ASP B OD1 1 
ATOM   7344  O OD2 . ASP B 1 387 ? 107.663 161.115 127.463 1.00 40.49  ? 387 ASP B OD2 1 
ATOM   7345  N N   . ARG B 1 388 ? 102.897 160.874 130.514 1.00 36.49  ? 388 ARG B N   1 
ATOM   7346  C CA  . ARG B 1 388 ? 101.684 161.461 131.111 1.00 35.98  ? 388 ARG B CA  1 
ATOM   7347  C C   . ARG B 1 388 ? 101.160 160.741 132.360 1.00 38.06  ? 388 ARG B C   1 
ATOM   7348  O O   . ARG B 1 388 ? 100.199 161.207 132.963 1.00 49.12  ? 388 ARG B O   1 
ATOM   7349  C CB  . ARG B 1 388 ? 100.615 161.693 130.034 1.00 34.95  ? 388 ARG B CB  1 
ATOM   7350  C CG  . ARG B 1 388 ? 99.957  160.417 129.505 1.00 39.96  ? 388 ARG B CG  1 
ATOM   7351  C CD  . ARG B 1 388 ? 99.089  160.684 128.271 1.00 42.49  ? 388 ARG B CD  1 
ATOM   7352  N NE  . ARG B 1 388 ? 99.898  161.106 127.108 1.00 48.12  ? 388 ARG B NE  1 
ATOM   7353  C CZ  . ARG B 1 388 ? 99.607  162.044 126.227 1.00 52.15  ? 388 ARG B CZ  1 
ATOM   7354  N NH1 . ARG B 1 388 ? 100.424 162.347 125.264 1.00 45.50  ? 388 ARG B NH1 1 
ATOM   7355  N NH2 . ARG B 1 388 ? 98.497  162.718 126.275 1.00 49.05  ? 388 ARG B NH2 1 
ATOM   7356  N N   . LEU B 1 389 ? 101.780 159.633 132.769 1.00 29.75  ? 389 LEU B N   1 
ATOM   7357  C CA  . LEU B 1 389 ? 101.417 158.843 133.954 1.00 22.38  ? 389 LEU B CA  1 
ATOM   7358  C C   . LEU B 1 389 ? 102.526 158.743 135.004 1.00 27.58  ? 389 LEU B C   1 
ATOM   7359  O O   . LEU B 1 389 ? 102.253 158.333 136.125 1.00 35.04  ? 389 LEU B O   1 
ATOM   7360  C CB  . LEU B 1 389 ? 100.979 157.438 133.525 1.00 28.34  ? 389 LEU B CB  1 
ATOM   7361  C CG  . LEU B 1 389 ? 99.605  157.388 132.851 1.00 27.26  ? 389 LEU B CG  1 
ATOM   7362  C CD1 . LEU B 1 389 ? 99.375  156.008 132.255 1.00 27.99  ? 389 LEU B CD1 1 
ATOM   7363  C CD2 . LEU B 1 389 ? 98.489  157.668 133.852 1.00 26.30  ? 389 LEU B CD2 1 
ATOM   7364  N N   . VAL B 1 390 ? 103.758 159.140 134.702 1.00 24.53  ? 390 VAL B N   1 
ATOM   7365  C CA  . VAL B 1 390 ? 104.897 159.047 135.626 1.00 26.50  ? 390 VAL B CA  1 
ATOM   7366  C C   . VAL B 1 390 ? 104.671 159.798 136.942 1.00 28.24  ? 390 VAL B C   1 
ATOM   7367  O O   . VAL B 1 390 ? 105.072 159.331 138.001 1.00 37.10  ? 390 VAL B O   1 
ATOM   7368  C CB  . VAL B 1 390 ? 106.183 159.489 134.909 1.00 28.26  ? 390 VAL B CB  1 
ATOM   7369  C CG1 . VAL B 1 390 ? 106.213 160.973 134.544 1.00 27.47  ? 390 VAL B CG1 1 
ATOM   7370  C CG2 . VAL B 1 390 ? 107.423 159.187 135.745 1.00 30.02  ? 390 VAL B CG2 1 
ATOM   7371  N N   . SER B 1 391 ? 103.950 160.918 136.919 1.00 31.34  ? 391 SER B N   1 
ATOM   7372  C CA  . SER B 1 391 ? 103.567 161.659 138.125 1.00 23.98  ? 391 SER B CA  1 
ATOM   7373  C C   . SER B 1 391 ? 102.581 160.875 139.004 1.00 26.49  ? 391 SER B C   1 
ATOM   7374  O O   . SER B 1 391 ? 102.713 160.886 140.225 1.00 34.89  ? 391 SER B O   1 
ATOM   7375  C CB  . SER B 1 391 ? 102.982 163.013 137.732 1.00 24.82  ? 391 SER B CB  1 
ATOM   7376  O OG  . SER B 1 391 ? 101.866 162.855 136.877 1.00 35.23  ? 391 SER B OG  1 
ATOM   7377  N N   . ARG B 1 392 ? 101.635 160.140 138.406 1.00 28.35  ? 392 ARG B N   1 
ATOM   7378  C CA  . ARG B 1 392 ? 100.726 159.218 139.100 1.00 20.04  ? 392 ARG B CA  1 
ATOM   7379  C C   . ARG B 1 392 ? 101.457 158.002 139.655 1.00 20.35  ? 392 ARG B C   1 
ATOM   7380  O O   . ARG B 1 392 ? 101.183 157.599 140.775 1.00 35.11  ? 392 ARG B O   1 
ATOM   7381  C CB  . ARG B 1 392 ? 99.582  158.824 138.161 1.00 27.91  ? 392 ARG B CB  1 
ATOM   7382  C CG  . ARG B 1 392 ? 98.556  157.911 138.844 1.00 22.94  ? 392 ARG B CG  1 
ATOM   7383  C CD  . ARG B 1 392 ? 97.304  157.709 137.994 1.00 33.01  ? 392 ARG B CD  1 
ATOM   7384  N NE  . ARG B 1 392 ? 96.510  158.954 137.892 1.00 45.97  ? 392 ARG B NE  1 
ATOM   7385  C CZ  . ARG B 1 392 ? 95.240  159.136 138.205 1.00 42.44  ? 392 ARG B CZ  1 
ATOM   7386  N NH1 . ARG B 1 392 ? 94.716  160.321 138.150 1.00 39.39  ? 392 ARG B NH1 1 
ATOM   7387  N NH2 . ARG B 1 392 ? 94.461  158.165 138.572 1.00 37.13  ? 392 ARG B NH2 1 
ATOM   7388  N N   . PHE B 1 393 ? 102.439 157.463 138.943 1.00 24.34  ? 393 PHE B N   1 
ATOM   7389  C CA  . PHE B 1 393 ? 103.285 156.379 139.439 1.00 10.16  ? 393 PHE B CA  1 
ATOM   7390  C C   . PHE B 1 393 ? 104.019 156.758 140.734 1.00 17.33  ? 393 PHE B C   1 
ATOM   7391  O O   . PHE B 1 393 ? 103.978 156.031 141.722 1.00 29.00  ? 393 PHE B O   1 
ATOM   7392  C CB  . PHE B 1 393 ? 104.283 155.966 138.354 1.00 14.00  ? 393 PHE B CB  1 
ATOM   7393  C CG  . PHE B 1 393 ? 105.064 154.720 138.696 1.00 17.89  ? 393 PHE B CG  1 
ATOM   7394  C CD1 . PHE B 1 393 ? 104.483 153.455 138.490 1.00 10.85  ? 393 PHE B CD1 1 
ATOM   7395  C CD2 . PHE B 1 393 ? 106.344 154.813 139.266 1.00 16.94  ? 393 PHE B CD2 1 
ATOM   7396  C CE1 . PHE B 1 393 ? 105.186 152.293 138.835 1.00 9.51   ? 393 PHE B CE1 1 
ATOM   7397  C CE2 . PHE B 1 393 ? 107.038 153.647 139.629 1.00 17.30  ? 393 PHE B CE2 1 
ATOM   7398  C CZ  . PHE B 1 393 ? 106.461 152.390 139.405 1.00 12.15  ? 393 PHE B CZ  1 
ATOM   7399  N N   . PHE B 1 394 ? 104.652 157.929 140.762 1.00 26.46  ? 394 PHE B N   1 
ATOM   7400  C CA  . PHE B 1 394 ? 105.364 158.400 141.944 1.00 15.58  ? 394 PHE B CA  1 
ATOM   7401  C C   . PHE B 1 394 ? 104.448 158.965 143.040 1.00 15.63  ? 394 PHE B C   1 
ATOM   7402  O O   . PHE B 1 394 ? 104.801 158.869 144.209 1.00 24.16  ? 394 PHE B O   1 
ATOM   7403  C CB  . PHE B 1 394 ? 106.503 159.326 141.530 1.00 17.93  ? 394 PHE B CB  1 
ATOM   7404  C CG  . PHE B 1 394 ? 107.632 158.567 140.860 1.00 19.60  ? 394 PHE B CG  1 
ATOM   7405  C CD1 . PHE B 1 394 ? 108.370 157.624 141.598 1.00 23.67  ? 394 PHE B CD1 1 
ATOM   7406  C CD2 . PHE B 1 394 ? 107.939 158.774 139.506 1.00 22.61  ? 394 PHE B CD2 1 
ATOM   7407  C CE1 . PHE B 1 394 ? 109.400 156.891 140.987 1.00 26.07  ? 394 PHE B CE1 1 
ATOM   7408  C CE2 . PHE B 1 394 ? 108.980 158.053 138.898 1.00 18.06  ? 394 PHE B CE2 1 
ATOM   7409  C CZ  . PHE B 1 394 ? 109.708 157.115 139.639 1.00 20.79  ? 394 PHE B CZ  1 
ATOM   7410  N N   . PHE B 1 395 ? 103.231 159.414 142.733 1.00 21.41  ? 395 PHE B N   1 
ATOM   7411  C CA  . PHE B 1 395 ? 102.187 159.607 143.736 1.00 16.85  ? 395 PHE B CA  1 
ATOM   7412  C C   . PHE B 1 395 ? 101.755 158.287 144.397 1.00 21.55  ? 395 PHE B C   1 
ATOM   7413  O O   . PHE B 1 395 ? 101.646 158.216 145.619 1.00 29.03  ? 395 PHE B O   1 
ATOM   7414  C CB  . PHE B 1 395 ? 100.992 160.319 143.103 1.00 19.00  ? 395 PHE B CB  1 
ATOM   7415  C CG  . PHE B 1 395 ? 99.809  160.454 144.033 1.00 25.43  ? 395 PHE B CG  1 
ATOM   7416  C CD1 . PHE B 1 395 ? 99.829  161.420 145.053 1.00 20.72  ? 395 PHE B CD1 1 
ATOM   7417  C CD2 . PHE B 1 395 ? 98.702  159.594 143.909 1.00 23.55  ? 395 PHE B CD2 1 
ATOM   7418  C CE1 . PHE B 1 395 ? 98.749  161.527 145.941 1.00 25.07  ? 395 PHE B CE1 1 
ATOM   7419  C CE2 . PHE B 1 395 ? 97.621  159.708 144.790 1.00 24.62  ? 395 PHE B CE2 1 
ATOM   7420  C CZ  . PHE B 1 395 ? 97.642  160.675 145.809 1.00 26.14  ? 395 PHE B CZ  1 
ATOM   7421  N N   . ASN B 1 396 ? 101.555 157.215 143.630 1.00 30.67  ? 396 ASN B N   1 
ATOM   7422  C CA  . ASN B 1 396 ? 101.246 155.889 144.168 1.00 18.26  ? 396 ASN B CA  1 
ATOM   7423  C C   . ASN B 1 396 ? 102.384 155.350 145.055 1.00 17.73  ? 396 ASN B C   1 
ATOM   7424  O O   . ASN B 1 396 ? 102.124 154.830 146.136 1.00 28.15  ? 396 ASN B O   1 
ATOM   7425  C CB  . ASN B 1 396 ? 100.956 154.921 143.012 1.00 17.22  ? 396 ASN B CB  1 
ATOM   7426  C CG  . ASN B 1 396 ? 99.680  155.200 142.247 1.00 20.73  ? 396 ASN B CG  1 
ATOM   7427  O OD1 . ASN B 1 396 ? 98.815  155.952 142.659 1.00 28.69  ? 396 ASN B OD1 1 
ATOM   7428  N ND2 . ASN B 1 396 ? 99.504  154.564 141.113 1.00 26.65  ? 396 ASN B ND2 1 
ATOM   7429  N N   . PHE B 1 397 ? 103.641 155.527 144.643 1.00 19.54  ? 397 PHE B N   1 
ATOM   7430  C CA  . PHE B 1 397 ? 104.824 155.223 145.447 1.00 8.69   ? 397 PHE B CA  1 
ATOM   7431  C C   . PHE B 1 397 ? 104.872 156.027 146.747 1.00 27.68  ? 397 PHE B C   1 
ATOM   7432  O O   . PHE B 1 397 ? 105.092 155.453 147.808 1.00 36.59  ? 397 PHE B O   1 
ATOM   7433  C CB  . PHE B 1 397 ? 106.081 155.508 144.626 1.00 13.60  ? 397 PHE B CB  1 
ATOM   7434  C CG  . PHE B 1 397 ? 107.378 155.448 145.399 1.00 23.85  ? 397 PHE B CG  1 
ATOM   7435  C CD1 . PHE B 1 397 ? 107.767 154.266 146.051 1.00 23.01  ? 397 PHE B CD1 1 
ATOM   7436  C CD2 . PHE B 1 397 ? 108.200 156.585 145.489 1.00 26.90  ? 397 PHE B CD2 1 
ATOM   7437  C CE1 . PHE B 1 397 ? 108.997 154.193 146.719 1.00 16.03  ? 397 PHE B CE1 1 
ATOM   7438  C CE2 . PHE B 1 397 ? 109.412 156.526 146.195 1.00 28.46  ? 397 PHE B CE2 1 
ATOM   7439  C CZ  . PHE B 1 397 ? 109.819 155.325 146.793 1.00 27.22  ? 397 PHE B CZ  1 
ATOM   7440  N N   . ALA B 1 398 ? 104.642 157.342 146.699 1.00 30.91  ? 398 ALA B N   1 
ATOM   7441  C CA  . ALA B 1 398 ? 104.621 158.193 147.880 1.00 11.33  ? 398 ALA B CA  1 
ATOM   7442  C C   . ALA B 1 398 ? 103.523 157.791 148.875 1.00 19.45  ? 398 ALA B C   1 
ATOM   7443  O O   . ALA B 1 398 ? 103.766 157.763 150.076 1.00 32.40  ? 398 ALA B O   1 
ATOM   7444  C CB  . ALA B 1 398 ? 104.460 159.642 147.423 1.00 23.88  ? 398 ALA B CB  1 
ATOM   7445  N N   . CYS B 1 399 ? 102.336 157.409 148.403 1.00 26.04  ? 399 CYS B N   1 
ATOM   7446  C CA  . CYS B 1 399 ? 101.272 156.893 149.261 1.00 23.70  ? 399 CYS B CA  1 
ATOM   7447  C C   . CYS B 1 399 ? 101.647 155.557 149.909 1.00 22.52  ? 399 CYS B C   1 
ATOM   7448  O O   . CYS B 1 399 ? 101.358 155.354 151.087 1.00 33.30  ? 399 CYS B O   1 
ATOM   7449  C CB  . CYS B 1 399 ? 99.967  156.785 148.466 1.00 27.96  ? 399 CYS B CB  1 
ATOM   7450  S SG  . CYS B 1 399 ? 99.455  158.436 147.949 1.00 38.78  ? 399 CYS B SG  1 
ATOM   7451  N N   . TYR B 1 400 ? 102.339 154.664 149.193 1.00 20.58  ? 400 TYR B N   1 
ATOM   7452  C CA  . TYR B 1 400 ? 102.819 153.411 149.773 1.00 14.04  ? 400 TYR B CA  1 
ATOM   7453  C C   . TYR B 1 400 ? 103.981 153.627 150.752 1.00 21.68  ? 400 TYR B C   1 
ATOM   7454  O O   . TYR B 1 400 ? 104.012 153.004 151.805 1.00 31.27  ? 400 TYR B O   1 
ATOM   7455  C CB  . TYR B 1 400 ? 103.157 152.395 148.677 1.00 11.33  ? 400 TYR B CB  1 
ATOM   7456  C CG  . TYR B 1 400 ? 103.233 150.973 149.204 1.00 20.38  ? 400 TYR B CG  1 
ATOM   7457  C CD1 . TYR B 1 400 ? 102.054 150.332 149.622 1.00 19.76  ? 400 TYR B CD1 1 
ATOM   7458  C CD2 . TYR B 1 400 ? 104.458 150.296 149.313 1.00 5.90   ? 400 TYR B CD2 1 
ATOM   7459  C CE1 . TYR B 1 400 ? 102.101 149.045 150.171 1.00 19.78  ? 400 TYR B CE1 1 
ATOM   7460  C CE2 . TYR B 1 400 ? 104.508 148.992 149.839 1.00 6.35   ? 400 TYR B CE2 1 
ATOM   7461  C CZ  . TYR B 1 400 ? 103.325 148.370 150.275 1.00 22.64  ? 400 TYR B CZ  1 
ATOM   7462  O OH  . TYR B 1 400 ? 103.330 147.119 150.799 1.00 31.03  ? 400 TYR B OH  1 
ATOM   7463  N N   . LEU B 1 401 ? 104.887 154.571 150.482 1.00 15.73  ? 401 LEU B N   1 
ATOM   7464  C CA  . LEU B 1 401 ? 105.904 155.005 151.439 1.00 18.62  ? 401 LEU B CA  1 
ATOM   7465  C C   . LEU B 1 401 ? 105.287 155.561 152.717 1.00 16.93  ? 401 LEU B C   1 
ATOM   7466  O O   . LEU B 1 401 ? 105.722 155.183 153.796 1.00 32.21  ? 401 LEU B O   1 
ATOM   7467  C CB  . LEU B 1 401 ? 106.801 156.103 150.843 1.00 25.57  ? 401 LEU B CB  1 
ATOM   7468  C CG  . LEU B 1 401 ? 108.079 155.639 150.149 1.00 24.97  ? 401 LEU B CG  1 
ATOM   7469  C CD1 . LEU B 1 401 ? 108.829 156.894 149.712 1.00 25.86  ? 401 LEU B CD1 1 
ATOM   7470  C CD2 . LEU B 1 401 ? 109.014 154.859 151.069 1.00 20.32  ? 401 LEU B CD2 1 
ATOM   7471  N N   . VAL B 1 402 ? 104.287 156.437 152.631 1.00 25.55  ? 402 VAL B N   1 
ATOM   7472  C CA  . VAL B 1 402 ? 103.618 156.991 153.814 1.00 22.25  ? 402 VAL B CA  1 
ATOM   7473  C C   . VAL B 1 402 ? 102.896 155.893 154.594 1.00 21.72  ? 402 VAL B C   1 
ATOM   7474  O O   . VAL B 1 402 ? 103.059 155.806 155.806 1.00 35.64  ? 402 VAL B O   1 
ATOM   7475  C CB  . VAL B 1 402 ? 102.686 158.149 153.424 1.00 26.62  ? 402 VAL B CB  1 
ATOM   7476  C CG1 . VAL B 1 402 ? 101.764 158.596 154.560 1.00 25.52  ? 402 VAL B CG1 1 
ATOM   7477  C CG2 . VAL B 1 402 ? 103.521 159.363 153.013 1.00 21.81  ? 402 VAL B CG2 1 
ATOM   7478  N N   . TYR B 1 403 ? 102.178 154.996 153.926 1.00 24.12  ? 403 TYR B N   1 
ATOM   7479  C CA  . TYR B 1 403 ? 101.596 153.819 154.562 1.00 20.00  ? 403 TYR B CA  1 
ATOM   7480  C C   . TYR B 1 403 ? 102.657 152.951 155.257 1.00 22.16  ? 403 TYR B C   1 
ATOM   7481  O O   . TYR B 1 403 ? 102.488 152.633 156.425 1.00 35.89  ? 403 TYR B O   1 
ATOM   7482  C CB  . TYR B 1 403 ? 100.764 153.058 153.524 1.00 20.24  ? 403 TYR B CB  1 
ATOM   7483  C CG  . TYR B 1 403 ? 100.340 151.656 153.905 1.00 26.76  ? 403 TYR B CG  1 
ATOM   7484  C CD1 . TYR B 1 403 ? 99.262  151.432 154.785 1.00 19.73  ? 403 TYR B CD1 1 
ATOM   7485  C CD2 . TYR B 1 403 ? 101.025 150.563 153.342 1.00 29.12  ? 403 TYR B CD2 1 
ATOM   7486  C CE1 . TYR B 1 403 ? 98.837  150.113 155.052 1.00 22.70  ? 403 TYR B CE1 1 
ATOM   7487  C CE2 . TYR B 1 403 ? 100.609 149.251 153.612 1.00 27.04  ? 403 TYR B CE2 1 
ATOM   7488  C CZ  . TYR B 1 403 ? 99.490  149.024 154.438 1.00 27.71  ? 403 TYR B CZ  1 
ATOM   7489  O OH  . TYR B 1 403 ? 99.022  147.757 154.598 1.00 37.47  ? 403 TYR B OH  1 
ATOM   7490  N N   . MET B 1 404 ? 103.780 152.626 154.617 1.00 23.17  ? 404 MET B N   1 
ATOM   7491  C CA  . MET B 1 404 ? 104.841 151.813 155.220 1.00 18.24  ? 404 MET B CA  1 
ATOM   7492  C C   . MET B 1 404 ? 105.656 152.521 156.300 1.00 18.31  ? 404 MET B C   1 
ATOM   7493  O O   . MET B 1 404 ? 106.109 151.872 157.241 1.00 27.92  ? 404 MET B O   1 
ATOM   7494  C CB  . MET B 1 404 ? 105.774 151.241 154.144 1.00 24.33  ? 404 MET B CB  1 
ATOM   7495  C CG  . MET B 1 404 ? 105.125 150.106 153.356 1.00 8.67   ? 404 MET B CG  1 
ATOM   7496  S SD  . MET B 1 404 ? 104.353 148.788 154.335 1.00 25.37  ? 404 MET B SD  1 
ATOM   7497  C CE  . MET B 1 404 ? 105.687 148.350 155.470 1.00 19.69  ? 404 MET B CE  1 
ATOM   7498  N N   . PHE B 1 405 ? 105.809 153.839 156.235 1.00 34.05  ? 405 PHE B N   1 
ATOM   7499  C CA  . PHE B 1 405 ? 106.345 154.646 157.326 1.00 19.76  ? 405 PHE B CA  1 
ATOM   7500  C C   . PHE B 1 405 ? 105.433 154.580 158.558 1.00 24.21  ? 405 PHE B C   1 
ATOM   7501  O O   . PHE B 1 405 ? 105.905 154.238 159.638 1.00 35.22  ? 405 PHE B O   1 
ATOM   7502  C CB  . PHE B 1 405 ? 106.547 156.084 156.844 1.00 22.76  ? 405 PHE B CB  1 
ATOM   7503  C CG  . PHE B 1 405 ? 106.972 157.033 157.939 1.00 37.81  ? 405 PHE B CG  1 
ATOM   7504  C CD1 . PHE B 1 405 ? 108.306 157.057 158.378 1.00 36.47  ? 405 PHE B CD1 1 
ATOM   7505  C CD2 . PHE B 1 405 ? 106.022 157.868 158.558 1.00 37.17  ? 405 PHE B CD2 1 
ATOM   7506  C CE1 . PHE B 1 405 ? 108.690 157.901 159.429 1.00 32.69  ? 405 PHE B CE1 1 
ATOM   7507  C CE2 . PHE B 1 405 ? 106.406 158.707 159.618 1.00 35.47  ? 405 PHE B CE2 1 
ATOM   7508  C CZ  . PHE B 1 405 ? 107.740 158.724 160.052 1.00 35.71  ? 405 PHE B CZ  1 
ATOM   7509  N N   . ILE B 1 406 ? 104.125 154.810 158.407 1.00 26.15  ? 406 ILE B N   1 
ATOM   7510  C CA  . ILE B 1 406 ? 103.150 154.673 159.501 1.00 25.43  ? 406 ILE B CA  1 
ATOM   7511  C C   . ILE B 1 406 ? 103.143 153.240 160.039 1.00 22.60  ? 406 ILE B C   1 
ATOM   7512  O O   . ILE B 1 406 ? 103.202 153.048 161.246 1.00 41.51  ? 406 ILE B O   1 
ATOM   7513  C CB  . ILE B 1 406 ? 101.744 155.134 159.055 1.00 32.73  ? 406 ILE B CB  1 
ATOM   7514  C CG1 . ILE B 1 406 ? 101.734 156.656 158.801 1.00 27.65  ? 406 ILE B CG1 1 
ATOM   7515  C CG2 . ILE B 1 406 ? 100.655 154.788 160.087 1.00 29.96  ? 406 ILE B CG2 1 
ATOM   7516  C CD1 . ILE B 1 406 ? 100.545 157.124 157.960 1.00 29.37  ? 406 ILE B CD1 1 
ATOM   7517  N N   . PHE B 1 407 ? 103.161 152.228 159.171 1.00 24.51  ? 407 PHE B N   1 
ATOM   7518  C CA  . PHE B 1 407 ? 103.250 150.821 159.553 1.00 19.44  ? 407 PHE B CA  1 
ATOM   7519  C C   . PHE B 1 407 ? 104.466 150.552 160.441 1.00 27.59  ? 407 PHE B C   1 
ATOM   7520  O O   . PHE B 1 407 ? 104.347 149.913 161.478 1.00 33.62  ? 407 PHE B O   1 
ATOM   7521  C CB  . PHE B 1 407 ? 103.285 149.949 158.287 1.00 21.91  ? 407 PHE B CB  1 
ATOM   7522  C CG  . PHE B 1 407 ? 102.631 148.590 158.406 1.00 26.88  ? 407 PHE B CG  1 
ATOM   7523  C CD1 . PHE B 1 407 ? 103.011 147.666 159.395 1.00 30.28  ? 407 PHE B CD1 1 
ATOM   7524  C CD2 . PHE B 1 407 ? 101.612 148.252 157.507 1.00 21.37  ? 407 PHE B CD2 1 
ATOM   7525  C CE1 . PHE B 1 407 ? 102.369 146.424 159.488 1.00 22.49  ? 407 PHE B CE1 1 
ATOM   7526  C CE2 . PHE B 1 407 ? 100.971 147.013 157.599 1.00 27.36  ? 407 PHE B CE2 1 
ATOM   7527  C CZ  . PHE B 1 407 ? 101.340 146.102 158.595 1.00 31.92  ? 407 PHE B CZ  1 
ATOM   7528  N N   . THR B 1 408 ? 105.631 151.074 160.068 1.00 29.24  ? 408 THR B N   1 
ATOM   7529  C CA  . THR B 1 408 ? 106.889 150.886 160.796 1.00 20.34  ? 408 THR B CA  1 
ATOM   7530  C C   . THR B 1 408 ? 106.889 151.596 162.138 1.00 25.95  ? 408 THR B C   1 
ATOM   7531  O O   . THR B 1 408 ? 107.240 150.987 163.142 1.00 41.51  ? 408 THR B O   1 
ATOM   7532  C CB  . THR B 1 408 ? 108.077 151.363 159.960 1.00 21.68  ? 408 THR B CB  1 
ATOM   7533  O OG1 . THR B 1 408 ? 108.036 150.728 158.720 1.00 29.67  ? 408 THR B OG1 1 
ATOM   7534  C CG2 . THR B 1 408 ? 109.424 151.026 160.576 1.00 22.10  ? 408 THR B CG2 1 
ATOM   7535  N N   . VAL B 1 409 ? 106.454 152.855 162.184 1.00 29.71  ? 409 VAL B N   1 
ATOM   7536  C CA  . VAL B 1 409 ? 106.314 153.616 163.427 1.00 28.52  ? 409 VAL B CA  1 
ATOM   7537  C C   . VAL B 1 409 ? 105.348 152.920 164.381 1.00 31.65  ? 409 VAL B C   1 
ATOM   7538  O O   . VAL B 1 409 ? 105.655 152.786 165.556 1.00 44.04  ? 409 VAL B O   1 
ATOM   7539  C CB  . VAL B 1 409 ? 105.879 155.063 163.138 1.00 30.59  ? 409 VAL B CB  1 
ATOM   7540  C CG1 . VAL B 1 409 ? 105.465 155.830 164.393 1.00 34.77  ? 409 VAL B CG1 1 
ATOM   7541  C CG2 . VAL B 1 409 ? 107.030 155.830 162.487 1.00 31.85  ? 409 VAL B CG2 1 
ATOM   7542  N N   . VAL B 1 410 ? 104.228 152.384 163.907 1.00 26.27  ? 410 VAL B N   1 
ATOM   7543  C CA  . VAL B 1 410 ? 103.257 151.665 164.742 1.00 32.22  ? 410 VAL B CA  1 
ATOM   7544  C C   . VAL B 1 410 ? 103.759 150.299 165.197 1.00 33.06  ? 410 VAL B C   1 
ATOM   7545  O O   . VAL B 1 410 ? 103.580 149.940 166.357 1.00 43.98  ? 410 VAL B O   1 
ATOM   7546  C CB  . VAL B 1 410 ? 101.926 151.530 163.991 1.00 34.58  ? 410 VAL B CB  1 
ATOM   7547  C CG1 . VAL B 1 410 ? 100.903 150.623 164.679 1.00 35.90  ? 410 VAL B CG1 1 
ATOM   7548  C CG2 . VAL B 1 410 ? 101.268 152.902 163.837 1.00 30.99  ? 410 VAL B CG2 1 
ATOM   7549  N N   . ALA B 1 411 ? 104.408 149.517 164.335 1.00 38.29  ? 411 ALA B N   1 
ATOM   7550  C CA  . ALA B 1 411 ? 104.959 148.218 164.716 1.00 35.52  ? 411 ALA B CA  1 
ATOM   7551  C C   . ALA B 1 411 ? 106.093 148.335 165.749 1.00 39.06  ? 411 ALA B C   1 
ATOM   7552  O O   . ALA B 1 411 ? 106.179 147.529 166.669 1.00 43.69  ? 411 ALA B O   1 
ATOM   7553  C CB  . ALA B 1 411 ? 105.420 147.501 163.449 1.00 35.36  ? 411 ALA B CB  1 
ATOM   7554  N N   . TYR B 1 412 ? 106.917 149.379 165.659 1.00 40.82  ? 412 TYR B N   1 
ATOM   7555  C CA  . TYR B 1 412 ? 107.991 149.648 166.608 1.00 37.29  ? 412 TYR B CA  1 
ATOM   7556  C C   . TYR B 1 412 ? 107.496 150.113 167.996 1.00 43.20  ? 412 TYR B C   1 
ATOM   7557  O O   . TYR B 1 412 ? 108.216 149.949 168.980 1.00 49.97  ? 412 TYR B O   1 
ATOM   7558  C CB  . TYR B 1 412 ? 108.939 150.661 165.965 1.00 38.24  ? 412 TYR B CB  1 
ATOM   7559  C CG  . TYR B 1 412 ? 110.214 150.916 166.743 1.00 45.39  ? 412 TYR B CG  1 
ATOM   7560  C CD1 . TYR B 1 412 ? 111.327 150.077 166.564 1.00 43.62  ? 412 TYR B CD1 1 
ATOM   7561  C CD2 . TYR B 1 412 ? 110.296 152.002 167.629 1.00 47.21  ? 412 TYR B CD2 1 
ATOM   7562  C CE1 . TYR B 1 412 ? 112.529 150.347 167.246 1.00 44.42  ? 412 TYR B CE1 1 
ATOM   7563  C CE2 . TYR B 1 412 ? 111.489 152.271 168.319 1.00 47.45  ? 412 TYR B CE2 1 
ATOM   7564  C CZ  . TYR B 1 412 ? 112.616 151.453 168.118 1.00 49.03  ? 412 TYR B CZ  1 
ATOM   7565  O OH  . TYR B 1 412 ? 113.763 151.720 168.793 1.00 49.61  ? 412 TYR B OH  1 
ATOM   7566  N N   . HIS B 1 413 ? 106.274 150.640 168.114 1.00 43.23  ? 413 HIS B N   1 
ATOM   7567  C CA  . HIS B 1 413 ? 105.692 151.162 169.360 1.00 42.12  ? 413 HIS B CA  1 
ATOM   7568  C C   . HIS B 1 413 ? 104.543 150.312 169.929 1.00 46.09  ? 413 HIS B C   1 
ATOM   7569  O O   . HIS B 1 413 ? 103.750 150.809 170.726 1.00 54.82  ? 413 HIS B O   1 
ATOM   7570  C CB  . HIS B 1 413 ? 105.306 152.640 169.203 1.00 40.56  ? 413 HIS B CB  1 
ATOM   7571  C CG  . HIS B 1 413 ? 106.465 153.559 168.942 1.00 41.51  ? 413 HIS B CG  1 
ATOM   7572  N ND1 . HIS B 1 413 ? 106.941 153.935 167.715 1.00 45.94  ? 413 HIS B ND1 1 
ATOM   7573  C CD2 . HIS B 1 413 ? 107.253 154.169 169.875 1.00 44.67  ? 413 HIS B CD2 1 
ATOM   7574  C CE1 . HIS B 1 413 ? 107.969 154.772 167.891 1.00 47.38  ? 413 HIS B CE1 1 
ATOM   7575  N NE2 . HIS B 1 413 ? 108.213 154.936 169.201 1.00 45.05  ? 413 HIS B NE2 1 
ATOM   7576  N N   . GLN B 1 414 ? 104.475 149.025 169.599 1.00 44.89  ? 414 GLN B N   1 
ATOM   7577  C CA  . GLN B 1 414 ? 103.533 148.101 170.231 1.00 48.82  ? 414 GLN B CA  1 
ATOM   7578  C C   . GLN B 1 414 ? 103.785 147.986 171.749 1.00 53.51  ? 414 GLN B C   1 
ATOM   7579  O O   . GLN B 1 414 ? 104.940 147.828 172.159 1.00 55.14  ? 414 GLN B O   1 
ATOM   7580  C CB  . GLN B 1 414 ? 103.645 146.711 169.589 1.00 49.37  ? 414 GLN B CB  1 
ATOM   7581  C CG  . GLN B 1 414 ? 103.233 146.714 168.114 1.00 48.87  ? 414 GLN B CG  1 
ATOM   7582  C CD  . GLN B 1 414 ? 101.779 147.092 167.915 1.00 52.71  ? 414 GLN B CD  1 
ATOM   7583  O OE1 . GLN B 1 414 ? 100.879 146.476 168.451 1.00 54.97  ? 414 GLN B OE1 1 
ATOM   7584  N NE2 . GLN B 1 414 ? 101.495 148.109 167.148 1.00 50.97  ? 414 GLN B NE2 1 
ATOM   7585  N N   . PRO B 1 415 ? 102.741 148.034 172.597 1.00 61.82  ? 415 PRO B N   1 
ATOM   7586  C CA  . PRO B 1 415 ? 102.875 147.842 174.038 1.00 61.01  ? 415 PRO B CA  1 
ATOM   7587  C C   . PRO B 1 415 ? 103.138 146.371 174.391 1.00 61.39  ? 415 PRO B C   1 
ATOM   7588  O O   . PRO B 1 415 ? 102.892 145.471 173.588 1.00 61.65  ? 415 PRO B O   1 
ATOM   7589  C CB  . PRO B 1 415 ? 101.551 148.343 174.625 1.00 60.53  ? 415 PRO B CB  1 
ATOM   7590  C CG  . PRO B 1 415 ? 100.543 148.018 173.528 1.00 59.50  ? 415 PRO B CG  1 
ATOM   7591  C CD  . PRO B 1 415 ? 101.343 148.252 172.249 1.00 59.05  ? 415 PRO B CD  1 
ATOM   7592  N N   . SER B 1 416 ? 103.599 146.116 175.616 1.00 66.75  ? 416 SER B N   1 
ATOM   7593  C CA  . SER B 1 416 ? 103.697 144.760 176.168 1.00 68.58  ? 416 SER B CA  1 
ATOM   7594  C C   . SER B 1 416 ? 102.316 144.096 176.272 1.00 70.01  ? 416 SER B C   1 
ATOM   7595  O O   . SER B 1 416 ? 101.318 144.763 176.556 1.00 69.71  ? 416 SER B O   1 
ATOM   7596  C CB  . SER B 1 416 ? 104.375 144.810 177.540 1.00 68.79  ? 416 SER B CB  1 
ATOM   7597  O OG  . SER B 1 416 ? 104.550 143.506 178.059 1.00 69.23  ? 416 SER B OG  1 
ATOM   7598  N N   . LEU B 1 417 ? 102.238 142.786 176.027 1.00 70.25  ? 417 LEU B N   1 
ATOM   7599  C CA  . LEU B 1 417 ? 100.974 142.043 175.988 1.00 71.33  ? 417 LEU B CA  1 
ATOM   7600  C C   . LEU B 1 417 ? 100.437 141.714 177.392 1.00 71.83  ? 417 LEU B C   1 
ATOM   7601  O O   . LEU B 1 417 ? 101.139 141.157 178.242 1.00 69.22  ? 417 LEU B O   1 
ATOM   7602  C CB  . LEU B 1 417 ? 101.101 140.785 175.107 1.00 69.38  ? 417 LEU B CB  1 
ATOM   7603  C CG  . LEU B 1 417 ? 101.655 141.026 173.687 1.00 70.14  ? 417 LEU B CG  1 
ATOM   7604  C CD1 . LEU B 1 417 ? 101.450 139.778 172.832 1.00 71.08  ? 417 LEU B CD1 1 
ATOM   7605  C CD2 . LEU B 1 417 ? 100.963 142.181 172.973 1.00 70.39  ? 417 LEU B CD2 1 
ATOM   7606  N N   . PHE B 1 429 ? 98.653  161.095 175.217 1.00 75.29  ? 429 PHE B N   1 
ATOM   7607  C CA  . PHE B 1 429 ? 98.621  161.509 173.817 1.00 76.49  ? 429 PHE B CA  1 
ATOM   7608  C C   . PHE B 1 429 ? 99.159  160.422 172.879 1.00 76.10  ? 429 PHE B C   1 
ATOM   7609  O O   . PHE B 1 429 ? 98.503  160.078 171.891 1.00 76.57  ? 429 PHE B O   1 
ATOM   7610  C CB  . PHE B 1 429 ? 99.424  162.808 173.662 1.00 75.45  ? 429 PHE B CB  1 
ATOM   7611  C CG  . PHE B 1 429 ? 99.662  163.228 172.223 1.00 75.47  ? 429 PHE B CG  1 
ATOM   7612  C CD1 . PHE B 1 429 ? 98.587  163.674 171.435 1.00 74.70  ? 429 PHE B CD1 1 
ATOM   7613  C CD2 . PHE B 1 429 ? 100.957 163.182 171.671 1.00 76.37  ? 429 PHE B CD2 1 
ATOM   7614  C CE1 . PHE B 1 429 ? 98.809  164.097 170.114 1.00 75.62  ? 429 PHE B CE1 1 
ATOM   7615  C CE2 . PHE B 1 429 ? 101.178 163.606 170.354 1.00 75.86  ? 429 PHE B CE2 1 
ATOM   7616  C CZ  . PHE B 1 429 ? 100.103 164.075 169.578 1.00 75.61  ? 429 PHE B CZ  1 
ATOM   7617  N N   . GLY B 1 430 ? 100.305 159.830 173.210 1.00 75.31  ? 430 GLY B N   1 
ATOM   7618  C CA  . GLY B 1 430 ? 100.966 158.803 172.402 1.00 73.39  ? 430 GLY B CA  1 
ATOM   7619  C C   . GLY B 1 430 ? 100.120 157.541 172.215 1.00 73.23  ? 430 GLY B C   1 
ATOM   7620  O O   . GLY B 1 430 ? 100.133 156.948 171.139 1.00 75.17  ? 430 GLY B O   1 
ATOM   7621  N N   . GLU B 1 431 ? 99.299  157.174 173.198 1.00 70.66  ? 431 GLU B N   1 
ATOM   7622  C CA  . GLU B 1 431 ? 98.334  156.079 173.076 1.00 69.47  ? 431 GLU B CA  1 
ATOM   7623  C C   . GLU B 1 431 ? 97.218  156.373 172.064 1.00 70.48  ? 431 GLU B C   1 
ATOM   7624  O O   . GLU B 1 431 ? 96.787  155.473 171.345 1.00 71.10  ? 431 GLU B O   1 
ATOM   7625  C CB  . GLU B 1 431 ? 97.739  155.805 174.455 1.00 68.59  ? 431 GLU B CB  1 
ATOM   7626  N N   . SER B 1 432 ? 96.782  157.633 171.937 1.00 70.20  ? 432 SER B N   1 
ATOM   7627  C CA  . SER B 1 432 ? 95.800  158.041 170.920 1.00 70.70  ? 432 SER B CA  1 
ATOM   7628  C C   . SER B 1 432 ? 96.402  158.066 169.509 1.00 70.93  ? 432 SER B C   1 
ATOM   7629  O O   . SER B 1 432 ? 95.784  157.595 168.561 1.00 70.10  ? 432 SER B O   1 
ATOM   7630  C CB  . SER B 1 432 ? 95.160  159.388 171.287 1.00 71.11  ? 432 SER B CB  1 
ATOM   7631  O OG  . SER B 1 432 ? 95.979  160.502 170.981 1.00 73.10  ? 432 SER B OG  1 
ATOM   7632  N N   . MET B 1 433 ? 97.652  158.522 169.366 1.00 67.85  ? 433 MET B N   1 
ATOM   7633  C CA  . MET B 1 433 ? 98.383  158.451 168.100 1.00 65.56  ? 433 MET B CA  1 
ATOM   7634  C C   . MET B 1 433 ? 98.682  157.011 167.677 1.00 65.22  ? 433 MET B C   1 
ATOM   7635  O O   . MET B 1 433 ? 98.624  156.698 166.491 1.00 68.18  ? 433 MET B O   1 
ATOM   7636  C CB  . MET B 1 433 ? 99.677  159.272 168.189 1.00 65.66  ? 433 MET B CB  1 
ATOM   7637  C CG  . MET B 1 433 ? 99.398  160.765 168.016 1.00 68.60  ? 433 MET B CG  1 
ATOM   7638  S SD  . MET B 1 433 ? 98.818  161.179 166.349 1.00 78.83  ? 433 MET B SD  1 
ATOM   7639  C CE  . MET B 1 433 ? 98.526  162.952 166.534 1.00 67.37  ? 433 MET B CE  1 
ATOM   7640  N N   . LEU B 1 434 ? 98.926  156.103 168.622 1.00 56.02  ? 434 LEU B N   1 
ATOM   7641  C CA  . LEU B 1 434 ? 99.064  154.681 168.329 1.00 56.03  ? 434 LEU B CA  1 
ATOM   7642  C C   . LEU B 1 434 ? 97.737  154.055 167.863 1.00 58.14  ? 434 LEU B C   1 
ATOM   7643  O O   . LEU B 1 434 ? 97.743  153.267 166.923 1.00 60.37  ? 434 LEU B O   1 
ATOM   7644  C CB  . LEU B 1 434 ? 99.658  153.968 169.556 1.00 57.75  ? 434 LEU B CB  1 
ATOM   7645  C CG  . LEU B 1 434 ? 100.044 152.507 169.283 1.00 57.04  ? 434 LEU B CG  1 
ATOM   7646  C CD1 . LEU B 1 434 ? 101.224 152.388 168.316 1.00 56.19  ? 434 LEU B CD1 1 
ATOM   7647  C CD2 . LEU B 1 434 ? 100.428 151.812 170.578 1.00 56.70  ? 434 LEU B CD2 1 
ATOM   7648  N N   . LEU B 1 435 ? 96.595  154.422 168.455 1.00 57.91  ? 435 LEU B N   1 
ATOM   7649  C CA  . LEU B 1 435 ? 95.267  154.013 167.973 1.00 59.40  ? 435 LEU B CA  1 
ATOM   7650  C C   . LEU B 1 435 ? 94.980  154.536 166.555 1.00 58.86  ? 435 LEU B C   1 
ATOM   7651  O O   . LEU B 1 435 ? 94.541  153.771 165.699 1.00 56.11  ? 435 LEU B O   1 
ATOM   7652  C CB  . LEU B 1 435 ? 94.202  154.483 168.977 1.00 61.73  ? 435 LEU B CB  1 
ATOM   7653  C CG  . LEU B 1 435 ? 92.747  154.202 168.563 1.00 60.67  ? 435 LEU B CG  1 
ATOM   7654  C CD1 . LEU B 1 435 ? 92.445  152.707 168.529 1.00 57.75  ? 435 LEU B CD1 1 
ATOM   7655  C CD2 . LEU B 1 435 ? 91.796  154.873 169.546 1.00 60.66  ? 435 LEU B CD2 1 
ATOM   7656  N N   . LEU B 1 436 ? 95.281  155.811 166.285 1.00 52.84  ? 436 LEU B N   1 
ATOM   7657  C CA  . LEU B 1 436 ? 95.164  156.394 164.948 1.00 50.75  ? 436 LEU B CA  1 
ATOM   7658  C C   . LEU B 1 436 ? 96.020  155.618 163.934 1.00 53.43  ? 436 LEU B C   1 
ATOM   7659  O O   . LEU B 1 436 ? 95.538  155.241 162.871 1.00 54.14  ? 436 LEU B O   1 
ATOM   7660  C CB  . LEU B 1 436 ? 95.544  157.886 164.997 1.00 50.72  ? 436 LEU B CB  1 
ATOM   7661  C CG  . LEU B 1 436 ? 95.511  158.580 163.623 1.00 51.81  ? 436 LEU B CG  1 
ATOM   7662  C CD1 . LEU B 1 436 ? 94.106  158.595 163.022 1.00 53.49  ? 436 LEU B CD1 1 
ATOM   7663  C CD2 . LEU B 1 436 ? 95.992  160.021 163.748 1.00 49.99  ? 436 LEU B CD2 1 
ATOM   7664  N N   . GLY B 1 437 ? 97.265  155.305 164.286 1.00 46.77  ? 437 GLY B N   1 
ATOM   7665  C CA  . GLY B 1 437 ? 98.145  154.485 163.465 1.00 41.77  ? 437 GLY B CA  1 
ATOM   7666  C C   . GLY B 1 437 ? 97.590  153.093 163.157 1.00 42.20  ? 437 GLY B C   1 
ATOM   7667  O O   . GLY B 1 437 ? 97.683  152.644 162.020 1.00 49.59  ? 437 GLY B O   1 
ATOM   7668  N N   . HIS B 1 438 ? 96.950  152.415 164.110 1.00 40.39  ? 438 HIS B N   1 
ATOM   7669  C CA  . HIS B 1 438 ? 96.308  151.122 163.844 1.00 43.77  ? 438 HIS B CA  1 
ATOM   7670  C C   . HIS B 1 438 ? 95.119  151.216 162.884 1.00 47.43  ? 438 HIS B C   1 
ATOM   7671  O O   . HIS B 1 438 ? 94.997  150.373 161.999 1.00 49.93  ? 438 HIS B O   1 
ATOM   7672  C CB  . HIS B 1 438 ? 95.868  150.441 165.142 1.00 48.39  ? 438 HIS B CB  1 
ATOM   7673  C CG  . HIS B 1 438 ? 97.005  149.861 165.932 1.00 48.02  ? 438 HIS B CG  1 
ATOM   7674  N ND1 . HIS B 1 438 ? 97.717  150.488 166.917 1.00 49.15  ? 438 HIS B ND1 1 
ATOM   7675  C CD2 . HIS B 1 438 ? 97.567  148.630 165.757 1.00 46.70  ? 438 HIS B CD2 1 
ATOM   7676  C CE1 . HIS B 1 438 ? 98.666  149.652 167.352 1.00 49.90  ? 438 HIS B CE1 1 
ATOM   7677  N NE2 . HIS B 1 438 ? 98.616  148.501 166.667 1.00 50.94  ? 438 HIS B NE2 1 
ATOM   7678  N N   . ILE B 1 439 ? 94.255  152.227 162.998 1.00 47.25  ? 439 ILE B N   1 
ATOM   7679  C CA  . ILE B 1 439 ? 93.135  152.370 162.057 1.00 45.54  ? 439 ILE B CA  1 
ATOM   7680  C C   . ILE B 1 439 ? 93.600  152.860 160.678 1.00 44.21  ? 439 ILE B C   1 
ATOM   7681  O O   . ILE B 1 439 ? 93.052  152.408 159.680 1.00 44.65  ? 439 ILE B O   1 
ATOM   7682  C CB  . ILE B 1 439 ? 91.956  153.179 162.634 1.00 49.87  ? 439 ILE B CB  1 
ATOM   7683  C CG1 . ILE B 1 439 ? 92.304  154.649 162.908 1.00 49.05  ? 439 ILE B CG1 1 
ATOM   7684  C CG2 . ILE B 1 439 ? 91.417  152.468 163.884 1.00 46.25  ? 439 ILE B CG2 1 
ATOM   7685  C CD1 . ILE B 1 439 ? 91.150  155.484 163.452 1.00 49.34  ? 439 ILE B CD1 1 
ATOM   7686  N N   . LEU B 1 440 ? 94.654  153.678 160.570 1.00 38.85  ? 440 LEU B N   1 
ATOM   7687  C CA  . LEU B 1 440 ? 95.286  153.981 159.281 1.00 37.92  ? 440 LEU B CA  1 
ATOM   7688  C C   . LEU B 1 440 ? 95.893  152.732 158.624 1.00 34.57  ? 440 LEU B C   1 
ATOM   7689  O O   . LEU B 1 440 ? 95.748  152.552 157.421 1.00 45.17  ? 440 LEU B O   1 
ATOM   7690  C CB  . LEU B 1 440 ? 96.338  155.092 159.449 1.00 41.19  ? 440 LEU B CB  1 
ATOM   7691  C CG  . LEU B 1 440 ? 95.762  156.476 159.803 1.00 40.88  ? 440 LEU B CG  1 
ATOM   7692  C CD1 . LEU B 1 440 ? 96.903  157.451 160.052 1.00 36.05  ? 440 LEU B CD1 1 
ATOM   7693  C CD2 . LEU B 1 440 ? 94.890  157.060 158.701 1.00 41.82  ? 440 LEU B CD2 1 
ATOM   7694  N N   . ILE B 1 441 ? 96.516  151.832 159.388 1.00 33.24  ? 441 ILE B N   1 
ATOM   7695  C CA  . ILE B 1 441 ? 97.011  150.537 158.888 1.00 35.26  ? 441 ILE B CA  1 
ATOM   7696  C C   . ILE B 1 441 ? 95.863  149.615 158.475 1.00 35.49  ? 441 ILE B C   1 
ATOM   7697  O O   . ILE B 1 441 ? 95.944  148.982 157.429 1.00 42.52  ? 441 ILE B O   1 
ATOM   7698  C CB  . ILE B 1 441 ? 97.919  149.876 159.946 1.00 40.87  ? 441 ILE B CB  1 
ATOM   7699  C CG1 . ILE B 1 441 ? 99.260  150.619 159.953 1.00 33.92  ? 441 ILE B CG1 1 
ATOM   7700  C CG2 . ILE B 1 441 ? 98.173  148.378 159.722 1.00 39.97  ? 441 ILE B CG2 1 
ATOM   7701  C CD1 . ILE B 1 441 ? 100.034 150.350 161.231 1.00 41.73  ? 441 ILE B CD1 1 
ATOM   7702  N N   . LEU B 1 442 ? 94.774  149.563 159.242 1.00 33.96  ? 442 LEU B N   1 
ATOM   7703  C CA  . LEU B 1 442 ? 93.571  148.818 158.870 1.00 34.35  ? 442 LEU B CA  1 
ATOM   7704  C C   . LEU B 1 442 ? 92.960  149.333 157.558 1.00 36.95  ? 442 LEU B C   1 
ATOM   7705  O O   . LEU B 1 442 ? 92.715  148.550 156.649 1.00 41.91  ? 442 LEU B O   1 
ATOM   7706  C CB  . LEU B 1 442 ? 92.562  148.876 160.027 1.00 36.29  ? 442 LEU B CB  1 
ATOM   7707  C CG  . LEU B 1 442 ? 91.234  148.156 159.755 1.00 36.85  ? 442 LEU B CG  1 
ATOM   7708  C CD1 . LEU B 1 442 ? 91.414  146.680 159.425 1.00 35.73  ? 442 LEU B CD1 1 
ATOM   7709  C CD2 . LEU B 1 442 ? 90.351  148.260 160.988 1.00 36.20  ? 442 LEU B CD2 1 
ATOM   7710  N N   . LEU B 1 443 ? 92.751  150.642 157.428 1.00 38.27  ? 443 LEU B N   1 
ATOM   7711  C CA  . LEU B 1 443 ? 92.177  151.260 156.232 1.00 36.53  ? 443 LEU B CA  1 
ATOM   7712  C C   . LEU B 1 443 ? 93.090  151.127 155.013 1.00 33.14  ? 443 LEU B C   1 
ATOM   7713  O O   . LEU B 1 443 ? 92.608  150.767 153.944 1.00 42.78  ? 443 LEU B O   1 
ATOM   7714  C CB  . LEU B 1 443 ? 91.862  152.738 156.508 1.00 38.93  ? 443 LEU B CB  1 
ATOM   7715  C CG  . LEU B 1 443 ? 90.704  152.962 157.492 1.00 39.46  ? 443 LEU B CG  1 
ATOM   7716  C CD1 . LEU B 1 443 ? 90.646  154.441 157.853 1.00 37.38  ? 443 LEU B CD1 1 
ATOM   7717  C CD2 . LEU B 1 443 ? 89.354  152.557 156.903 1.00 37.28  ? 443 LEU B CD2 1 
ATOM   7718  N N   . GLY B 1 444 ? 94.400  151.338 155.161 1.00 27.99  ? 444 GLY B N   1 
ATOM   7719  C CA  . GLY B 1 444 ? 95.376  151.082 154.104 1.00 21.98  ? 444 GLY B CA  1 
ATOM   7720  C C   . GLY B 1 444 ? 95.432  149.614 153.690 1.00 23.34  ? 444 GLY B C   1 
ATOM   7721  O O   . GLY B 1 444 ? 95.473  149.314 152.504 1.00 36.02  ? 444 GLY B O   1 
ATOM   7722  N N   . GLY B 1 445 ? 95.328  148.690 154.641 1.00 29.28  ? 445 GLY B N   1 
ATOM   7723  C CA  . GLY B 1 445 ? 95.209  147.262 154.376 1.00 29.43  ? 445 GLY B CA  1 
ATOM   7724  C C   . GLY B 1 445 ? 93.933  146.893 153.627 1.00 28.20  ? 445 GLY B C   1 
ATOM   7725  O O   . GLY B 1 445 ? 94.006  146.161 152.650 1.00 36.99  ? 445 GLY B O   1 
ATOM   7726  N N   . ILE B 1 446 ? 92.774  147.428 154.016 1.00 33.74  ? 446 ILE B N   1 
ATOM   7727  C CA  . ILE B 1 446 ? 91.506  147.231 153.298 1.00 33.25  ? 446 ILE B CA  1 
ATOM   7728  C C   . ILE B 1 446 ? 91.582  147.829 151.890 1.00 33.32  ? 446 ILE B C   1 
ATOM   7729  O O   . ILE B 1 446 ? 91.224  147.163 150.927 1.00 35.91  ? 446 ILE B O   1 
ATOM   7730  C CB  . ILE B 1 446 ? 90.318  147.809 154.103 1.00 34.57  ? 446 ILE B CB  1 
ATOM   7731  C CG1 . ILE B 1 446 ? 90.064  146.965 155.368 1.00 30.51  ? 446 ILE B CG1 1 
ATOM   7732  C CG2 . ILE B 1 446 ? 89.030  147.863 153.262 1.00 30.88  ? 446 ILE B CG2 1 
ATOM   7733  C CD1 . ILE B 1 446 ? 89.217  147.694 156.416 1.00 31.51  ? 446 ILE B CD1 1 
ATOM   7734  N N   . TYR B 1 447 ? 92.089  149.049 151.738 1.00 26.21  ? 447 TYR B N   1 
ATOM   7735  C CA  . TYR B 1 447 ? 92.238  149.702 150.444 1.00 23.97  ? 447 TYR B CA  1 
ATOM   7736  C C   . TYR B 1 447 ? 93.122  148.906 149.479 1.00 32.00  ? 447 TYR B C   1 
ATOM   7737  O O   . TYR B 1 447 ? 92.733  148.667 148.338 1.00 47.99  ? 447 TYR B O   1 
ATOM   7738  C CB  . TYR B 1 447 ? 92.820  151.095 150.665 1.00 27.58  ? 447 TYR B CB  1 
ATOM   7739  C CG  . TYR B 1 447 ? 93.010  151.873 149.385 1.00 39.32  ? 447 TYR B CG  1 
ATOM   7740  C CD1 . TYR B 1 447 ? 91.956  152.662 148.905 1.00 32.78  ? 447 TYR B CD1 1 
ATOM   7741  C CD2 . TYR B 1 447 ? 94.213  151.784 148.655 1.00 35.10  ? 447 TYR B CD2 1 
ATOM   7742  C CE1 . TYR B 1 447 ? 92.103  153.377 147.713 1.00 34.84  ? 447 TYR B CE1 1 
ATOM   7743  C CE2 . TYR B 1 447 ? 94.359  152.493 147.449 1.00 34.28  ? 447 TYR B CE2 1 
ATOM   7744  C CZ  . TYR B 1 447 ? 93.300  153.290 146.978 1.00 38.42  ? 447 TYR B CZ  1 
ATOM   7745  O OH  . TYR B 1 447 ? 93.411  153.958 145.807 1.00 40.61  ? 447 TYR B OH  1 
ATOM   7746  N N   . LEU B 1 448 ? 94.291  148.458 149.932 1.00 18.73  ? 448 LEU B N   1 
ATOM   7747  C CA  . LEU B 1 448 ? 95.185  147.627 149.135 1.00 19.00  ? 448 LEU B CA  1 
ATOM   7748  C C   . LEU B 1 448 ? 94.562  146.267 148.824 1.00 24.44  ? 448 LEU B C   1 
ATOM   7749  O O   . LEU B 1 448 ? 94.680  145.793 147.699 1.00 31.24  ? 448 LEU B O   1 
ATOM   7750  C CB  . LEU B 1 448 ? 96.522  147.470 149.867 1.00 23.73  ? 448 LEU B CB  1 
ATOM   7751  C CG  . LEU B 1 448 ? 97.349  148.761 149.914 1.00 30.49  ? 448 LEU B CG  1 
ATOM   7752  C CD1 . LEU B 1 448 ? 98.432  148.621 150.971 1.00 27.41  ? 448 LEU B CD1 1 
ATOM   7753  C CD2 . LEU B 1 448 ? 98.015  149.069 148.577 1.00 31.78  ? 448 LEU B CD2 1 
ATOM   7754  N N   . LEU B 1 449 ? 93.850  145.658 149.771 1.00 28.61  ? 449 LEU B N   1 
ATOM   7755  C CA  . LEU B 1 449 ? 93.141  144.398 149.581 1.00 29.67  ? 449 LEU B CA  1 
ATOM   7756  C C   . LEU B 1 449 ? 92.060  144.531 148.501 1.00 27.67  ? 449 LEU B C   1 
ATOM   7757  O O   . LEU B 1 449 ? 92.051  143.748 147.562 1.00 33.28  ? 449 LEU B O   1 
ATOM   7758  C CB  . LEU B 1 449 ? 92.575  143.935 150.936 1.00 33.70  ? 449 LEU B CB  1 
ATOM   7759  C CG  . LEU B 1 449 ? 91.783  142.628 150.918 1.00 31.24  ? 449 LEU B CG  1 
ATOM   7760  C CD1 . LEU B 1 449 ? 92.633  141.475 150.412 1.00 28.21  ? 449 LEU B CD1 1 
ATOM   7761  C CD2 . LEU B 1 449 ? 91.317  142.305 152.331 1.00 29.05  ? 449 LEU B CD2 1 
ATOM   7762  N N   . LEU B 1 450 ? 91.205  145.553 148.570 1.00 32.41  ? 450 LEU B N   1 
ATOM   7763  C CA  . LEU B 1 450 ? 90.178  145.818 147.559 1.00 30.01  ? 450 LEU B CA  1 
ATOM   7764  C C   . LEU B 1 450 ? 90.789  146.101 146.188 1.00 28.05  ? 450 LEU B C   1 
ATOM   7765  O O   . LEU B 1 450 ? 90.350  145.522 145.199 1.00 41.04  ? 450 LEU B O   1 
ATOM   7766  C CB  . LEU B 1 450 ? 89.288  146.988 148.004 1.00 29.88  ? 450 LEU B CB  1 
ATOM   7767  C CG  . LEU B 1 450 ? 88.396  146.671 149.213 1.00 31.33  ? 450 LEU B CG  1 
ATOM   7768  C CD1 . LEU B 1 450 ? 87.714  147.947 149.686 1.00 30.20  ? 450 LEU B CD1 1 
ATOM   7769  C CD2 . LEU B 1 450 ? 87.316  145.648 148.886 1.00 29.99  ? 450 LEU B CD2 1 
ATOM   7770  N N   . GLY B 1 451 ? 91.837  146.920 146.119 1.00 26.14  ? 451 GLY B N   1 
ATOM   7771  C CA  . GLY B 1 451 ? 92.532  147.203 144.869 1.00 19.13  ? 451 GLY B CA  1 
ATOM   7772  C C   . GLY B 1 451 ? 93.157  145.969 144.220 1.00 23.95  ? 451 GLY B C   1 
ATOM   7773  O O   . GLY B 1 451 ? 93.143  145.838 143.000 1.00 37.48  ? 451 GLY B O   1 
ATOM   7774  N N   . GLN B 1 452 ? 93.637  145.040 145.050 1.00 27.07  ? 452 GLN B N   1 
ATOM   7775  C CA  . GLN B 1 452 ? 94.303  143.817 144.519 1.00 25.63  ? 452 GLN B CA  1 
ATOM   7776  C C   . GLN B 1 452 ? 93.232  142.785 144.130 1.00 27.30  ? 452 GLN B C   1 
ATOM   7777  O O   . GLN B 1 452 ? 93.369  142.200 143.037 1.00 39.57  ? 452 GLN B O   1 
ATOM   7778  C CB  . GLN B 1 452 ? 95.376  143.374 145.521 1.00 30.95  ? 452 GLN B CB  1 
ATOM   7779  C CG  . GLN B 1 452 ? 96.553  144.360 145.546 1.00 27.79  ? 452 GLN B CG  1 
ATOM   7780  C CD  . GLN B 1 452 ? 97.452  144.202 144.344 1.00 28.95  ? 452 GLN B CD  1 
ATOM   7781  O OE1 . GLN B 1 452 ? 97.337  143.246 143.579 1.00 36.07  ? 452 GLN B OE1 1 
ATOM   7782  N NE2 . GLN B 1 452 ? 98.366  145.142 144.173 1.00 39.24  ? 452 GLN B NE2 1 
ATOM   7783  N N   . LEU B 1 453 ? 92.209  142.569 144.965 1.00 32.99  ? 453 LEU B N   1 
ATOM   7784  C CA  . LEU B 1 453 ? 91.099  141.695 144.581 1.00 31.52  ? 453 LEU B CA  1 
ATOM   7785  C C   . LEU B 1 453 ? 90.459  142.165 143.271 1.00 29.21  ? 453 LEU B C   1 
ATOM   7786  O O   . LEU B 1 453 ? 90.138  141.349 142.415 1.00 37.05  ? 453 LEU B O   1 
ATOM   7787  C CB  . LEU B 1 453 ? 90.056  141.634 145.710 1.00 32.78  ? 453 LEU B CB  1 
ATOM   7788  C CG  . LEU B 1 453 ? 90.532  140.925 146.984 1.00 32.27  ? 453 LEU B CG  1 
ATOM   7789  C CD1 . LEU B 1 453 ? 89.482  141.100 148.074 1.00 32.35  ? 453 LEU B CD1 1 
ATOM   7790  C CD2 . LEU B 1 453 ? 90.763  139.433 146.769 1.00 29.54  ? 453 LEU B CD2 1 
ATOM   7791  N N   . TRP B 1 454 ? 90.334  143.479 143.074 1.00 30.12  ? 454 TRP B N   1 
ATOM   7792  C CA  . TRP B 1 454 ? 89.881  144.069 141.819 1.00 29.15  ? 454 TRP B CA  1 
ATOM   7793  C C   . TRP B 1 454 ? 90.838  143.807 140.648 1.00 29.78  ? 454 TRP B C   1 
ATOM   7794  O O   . TRP B 1 454 ? 90.374  143.472 139.563 1.00 41.71  ? 454 TRP B O   1 
ATOM   7795  C CB  . TRP B 1 454 ? 89.636  145.563 142.030 1.00 29.99  ? 454 TRP B CB  1 
ATOM   7796  C CG  . TRP B 1 454 ? 89.142  146.317 140.837 1.00 39.68  ? 454 TRP B CG  1 
ATOM   7797  C CD1 . TRP B 1 454 ? 87.961  146.104 140.213 1.00 38.20  ? 454 TRP B CD1 1 
ATOM   7798  C CD2 . TRP B 1 454 ? 89.780  147.408 140.109 1.00 38.97  ? 454 TRP B CD2 1 
ATOM   7799  N NE1 . TRP B 1 454 ? 87.818  146.999 139.174 1.00 33.21  ? 454 TRP B NE1 1 
ATOM   7800  C CE2 . TRP B 1 454 ? 88.896  147.845 139.084 1.00 37.17  ? 454 TRP B CE2 1 
ATOM   7801  C CE3 . TRP B 1 454 ? 91.020  148.077 140.215 1.00 34.63  ? 454 TRP B CE3 1 
ATOM   7802  C CZ2 . TRP B 1 454 ? 89.214  148.899 138.218 1.00 40.94  ? 454 TRP B CZ2 1 
ATOM   7803  C CZ3 . TRP B 1 454 ? 91.339  149.150 139.363 1.00 41.27  ? 454 TRP B CZ3 1 
ATOM   7804  C CH2 . TRP B 1 454 ? 90.439  149.567 138.368 1.00 38.92  ? 454 TRP B CH2 1 
ATOM   7805  N N   . TYR B 1 455 ? 92.157  143.856 140.851 1.00 35.86  ? 455 TYR B N   1 
ATOM   7806  C CA  . TYR B 1 455 ? 93.131  143.438 139.840 1.00 32.60  ? 455 TYR B CA  1 
ATOM   7807  C C   . TYR B 1 455 ? 92.904  141.988 139.405 1.00 32.49  ? 455 TYR B C   1 
ATOM   7808  O O   . TYR B 1 455 ? 92.713  141.719 138.221 1.00 40.82  ? 455 TYR B O   1 
ATOM   7809  C CB  . TYR B 1 455 ? 94.569  143.630 140.344 1.00 34.39  ? 455 TYR B CB  1 
ATOM   7810  C CG  . TYR B 1 455 ? 95.624  143.126 139.376 1.00 36.31  ? 455 TYR B CG  1 
ATOM   7811  C CD1 . TYR B 1 455 ? 96.084  143.962 138.344 1.00 33.92  ? 455 TYR B CD1 1 
ATOM   7812  C CD2 . TYR B 1 455 ? 96.112  141.808 139.469 1.00 33.24  ? 455 TYR B CD2 1 
ATOM   7813  C CE1 . TYR B 1 455 ? 97.022  143.491 137.412 1.00 33.68  ? 455 TYR B CE1 1 
ATOM   7814  C CE2 . TYR B 1 455 ? 97.035  141.322 138.527 1.00 37.03  ? 455 TYR B CE2 1 
ATOM   7815  C CZ  . TYR B 1 455 ? 97.504  142.171 137.501 1.00 40.58  ? 455 TYR B CZ  1 
ATOM   7816  O OH  . TYR B 1 455 ? 98.430  141.735 136.607 1.00 41.54  ? 455 TYR B OH  1 
ATOM   7817  N N   . PHE B 1 456 ? 92.862  141.045 140.346 1.00 33.35  ? 456 PHE B N   1 
ATOM   7818  C CA  . PHE B 1 456 ? 92.658  139.639 140.009 1.00 31.80  ? 456 PHE B CA  1 
ATOM   7819  C C   . PHE B 1 456 ? 91.269  139.340 139.445 1.00 37.82  ? 456 PHE B C   1 
ATOM   7820  O O   . PHE B 1 456 ? 91.152  138.448 138.613 1.00 44.84  ? 456 PHE B O   1 
ATOM   7821  C CB  . PHE B 1 456 ? 93.001  138.752 141.204 1.00 33.13  ? 456 PHE B CB  1 
ATOM   7822  C CG  . PHE B 1 456 ? 94.490  138.674 141.460 1.00 37.52  ? 456 PHE B CG  1 
ATOM   7823  C CD1 . PHE B 1 456 ? 95.338  138.150 140.468 1.00 39.77  ? 456 PHE B CD1 1 
ATOM   7824  C CD2 . PHE B 1 456 ? 95.035  139.147 142.664 1.00 34.64  ? 456 PHE B CD2 1 
ATOM   7825  C CE1 . PHE B 1 456 ? 96.724  138.103 140.674 1.00 38.82  ? 456 PHE B CE1 1 
ATOM   7826  C CE2 . PHE B 1 456 ? 96.422  139.096 142.872 1.00 32.52  ? 456 PHE B CE2 1 
ATOM   7827  C CZ  . PHE B 1 456 ? 97.264  138.573 141.879 1.00 36.83  ? 456 PHE B CZ  1 
ATOM   7828  N N   . TRP B 1 457 ? 90.233  140.102 139.797 1.00 39.02  ? 457 TRP B N   1 
ATOM   7829  C CA  . TRP B 1 457 ? 88.937  140.025 139.127 1.00 38.16  ? 457 TRP B CA  1 
ATOM   7830  C C   . TRP B 1 457 ? 89.005  140.483 137.667 1.00 43.87  ? 457 TRP B C   1 
ATOM   7831  O O   . TRP B 1 457 ? 88.574  139.762 136.768 1.00 48.05  ? 457 TRP B O   1 
ATOM   7832  C CB  . TRP B 1 457 ? 87.889  140.826 139.895 1.00 44.26  ? 457 TRP B CB  1 
ATOM   7833  C CG  . TRP B 1 457 ? 86.523  140.712 139.300 1.00 48.56  ? 457 TRP B CG  1 
ATOM   7834  C CD1 . TRP B 1 457 ? 85.843  141.699 138.678 1.00 47.80  ? 457 TRP B CD1 1 
ATOM   7835  C CD2 . TRP B 1 457 ? 85.667  139.532 139.244 1.00 45.67  ? 457 TRP B CD2 1 
ATOM   7836  N NE1 . TRP B 1 457 ? 84.629  141.212 138.243 1.00 48.59  ? 457 TRP B NE1 1 
ATOM   7837  C CE2 . TRP B 1 457 ? 84.467  139.879 138.558 1.00 46.65  ? 457 TRP B CE2 1 
ATOM   7838  C CE3 . TRP B 1 457 ? 85.787  138.202 139.698 1.00 45.69  ? 457 TRP B CE3 1 
ATOM   7839  C CZ2 . TRP B 1 457 ? 83.441  138.956 138.338 1.00 46.50  ? 457 TRP B CZ2 1 
ATOM   7840  C CZ3 . TRP B 1 457 ? 84.762  137.263 139.474 1.00 46.27  ? 457 TRP B CZ3 1 
ATOM   7841  C CH2 . TRP B 1 457 ? 83.593  137.639 138.795 1.00 46.80  ? 457 TRP B CH2 1 
ATOM   7842  N N   . ARG B 1 458 ? 89.618  141.641 137.403 1.00 38.90  ? 458 ARG B N   1 
ATOM   7843  C CA  . ARG B 1 458 ? 89.756  142.133 136.000 1.00 37.22  ? 458 ARG B CA  1 
ATOM   7844  C C   . ARG B 1 458 ? 90.586  141.153 135.165 1.00 40.39  ? 458 ARG B C   1 
ATOM   7845  O O   . ARG B 1 458 ? 90.235  140.946 133.987 1.00 48.20  ? 458 ARG B O   1 
ATOM   7846  C CB  . ARG B 1 458 ? 90.364  143.534 135.997 1.00 37.89  ? 458 ARG B CB  1 
ATOM   7847  C CG  . ARG B 1 458 ? 89.335  144.593 136.389 1.00 33.03  ? 458 ARG B CG  1 
ATOM   7848  C CD  . ARG B 1 458 ? 89.902  145.993 136.147 1.00 35.18  ? 458 ARG B CD  1 
ATOM   7849  N NE  . ARG B 1 458 ? 90.926  146.322 137.129 1.00 36.16  ? 458 ARG B NE  1 
ATOM   7850  C CZ  . ARG B 1 458 ? 92.211  146.005 137.018 1.00 40.16  ? 458 ARG B CZ  1 
ATOM   7851  N NH1 . ARG B 1 458 ? 93.062  146.350 137.968 1.00 40.88  ? 458 ARG B NH1 1 
ATOM   7852  N NH2 . ARG B 1 458 ? 92.641  145.340 135.960 1.00 40.85  ? 458 ARG B NH2 1 
ATOM   7853  N N   . ARG B 1 459 ? 91.614  140.556 135.788 1.00 39.12  ? 459 ARG B N   1 
ATOM   7854  C CA  . ARG B 1 459 ? 92.542  139.629 135.086 1.00 40.05  ? 459 ARG B CA  1 
ATOM   7855  C C   . ARG B 1 459 ? 92.180  138.158 135.381 1.00 46.58  ? 459 ARG B C   1 
ATOM   7856  O O   . ARG B 1 459 ? 93.107  137.325 135.344 1.00 50.00  ? 459 ARG B O   1 
ATOM   7857  C CB  . ARG B 1 459 ? 93.988  139.902 135.554 1.00 35.85  ? 459 ARG B CB  1 
ATOM   7858  C CG  . ARG B 1 459 ? 94.471  141.356 135.354 1.00 36.77  ? 459 ARG B CG  1 
ATOM   7859  C CD  . ARG B 1 459 ? 94.442  141.810 133.892 1.00 38.05  ? 459 ARG B CD  1 
ATOM   7860  N NE  . ARG B 1 459 ? 94.648  143.246 133.764 1.00 37.44  ? 459 ARG B NE  1 
ATOM   7861  C CZ  . ARG B 1 459 ? 94.477  143.934 132.641 1.00 43.68  ? 459 ARG B CZ  1 
ATOM   7862  N NH1 . ARG B 1 459 ? 94.688  145.239 132.626 1.00 43.29  ? 459 ARG B NH1 1 
ATOM   7863  N NH2 . ARG B 1 459 ? 94.089  143.317 131.541 1.00 41.17  ? 459 ARG B NH2 1 
ATOM   7864  N N   . ARG B 1 460 ? 90.888  137.839 135.590 1.00 52.55  ? 460 ARG B N   1 
ATOM   7865  C CA  . ARG B 1 460 ? 90.456  136.455 135.986 1.00 50.21  ? 460 ARG B CA  1 
ATOM   7866  C C   . ARG B 1 460 ? 90.536  135.468 134.812 1.00 53.20  ? 460 ARG B C   1 
ATOM   7867  O O   . ARG B 1 460 ? 90.886  134.299 135.061 1.00 53.61  ? 460 ARG B O   1 
ATOM   7868  C CB  . ARG B 1 460 ? 89.068  136.469 136.650 1.00 49.37  ? 460 ARG B CB  1 
ATOM   7869  C CG  . ARG B 1 460 ? 87.920  136.826 135.698 1.00 47.51  ? 460 ARG B CG  1 
ATOM   7870  C CD  . ARG B 1 460 ? 86.642  137.120 136.479 1.00 49.21  ? 460 ARG B CD  1 
ATOM   7871  N NE  . ARG B 1 460 ? 85.565  137.633 135.646 1.00 52.75  ? 460 ARG B NE  1 
ATOM   7872  C CZ  . ARG B 1 460 ? 85.346  138.921 135.406 1.00 54.17  ? 460 ARG B CZ  1 
ATOM   7873  N NH1 . ARG B 1 460 ? 84.337  139.289 134.635 1.00 51.21  ? 460 ARG B NH1 1 
ATOM   7874  N NH2 . ARG B 1 460 ? 86.136  139.837 135.938 1.00 54.53  ? 460 ARG B NH2 1 
ATOM   7875  N N   . LEU B 1 461 ? 90.236  135.914 133.595 1.00 52.83  ? 461 LEU B N   1 
ATOM   7876  C CA  . LEU B 1 461 ? 90.237  135.066 132.391 1.00 52.06  ? 461 LEU B CA  1 
ATOM   7877  C C   . LEU B 1 461 ? 91.639  134.554 132.013 1.00 52.62  ? 461 LEU B C   1 
ATOM   7878  O O   . LEU B 1 461 ? 91.767  133.548 131.320 1.00 54.38  ? 461 LEU B O   1 
ATOM   7879  C CB  . LEU B 1 461 ? 89.611  135.835 131.212 1.00 55.68  ? 461 LEU B CB  1 
ATOM   7880  C CG  . LEU B 1 461 ? 88.163  136.320 131.420 1.00 56.25  ? 461 LEU B CG  1 
ATOM   7881  C CD1 . LEU B 1 461 ? 87.706  137.120 130.208 1.00 51.91  ? 461 LEU B CD1 1 
ATOM   7882  C CD2 . LEU B 1 461 ? 87.191  135.167 131.617 1.00 53.10  ? 461 LEU B CD2 1 
ATOM   7883  N N   . PHE B 1 462 ? 92.688  135.227 132.493 1.00 50.24  ? 462 PHE B N   1 
ATOM   7884  C CA  . PHE B 1 462 ? 94.100  134.916 132.244 1.00 51.06  ? 462 PHE B CA  1 
ATOM   7885  C C   . PHE B 1 462 ? 94.896  134.864 133.558 1.00 49.29  ? 462 PHE B C   1 
ATOM   7886  O O   . PHE B 1 462 ? 96.076  135.216 133.619 1.00 51.17  ? 462 PHE B O   1 
ATOM   7887  C CB  . PHE B 1 462 ? 94.673  135.913 131.219 1.00 49.11  ? 462 PHE B CB  1 
ATOM   7888  C CG  . PHE B 1 462 ? 94.032  135.807 129.851 1.00 46.83  ? 462 PHE B CG  1 
ATOM   7889  C CD1 . PHE B 1 462 ? 94.532  134.891 128.911 1.00 47.83  ? 462 PHE B CD1 1 
ATOM   7890  C CD2 . PHE B 1 462 ? 92.914  136.597 129.527 1.00 48.81  ? 462 PHE B CD2 1 
ATOM   7891  C CE1 . PHE B 1 462 ? 93.912  134.754 127.656 1.00 49.97  ? 462 PHE B CE1 1 
ATOM   7892  C CE2 . PHE B 1 462 ? 92.291  136.457 128.276 1.00 52.02  ? 462 PHE B CE2 1 
ATOM   7893  C CZ  . PHE B 1 462 ? 92.790  135.540 127.341 1.00 49.41  ? 462 PHE B CZ  1 
ATOM   7894  N N   . ILE B 1 463 ? 94.252  134.455 134.653 1.00 51.99  ? 463 ILE B N   1 
ATOM   7895  C CA  . ILE B 1 463 ? 94.797  134.661 135.996 1.00 56.47  ? 463 ILE B CA  1 
ATOM   7896  C C   . ILE B 1 463 ? 96.139  133.950 136.210 1.00 54.74  ? 463 ILE B C   1 
ATOM   7897  O O   . ILE B 1 463 ? 97.061  134.575 136.723 1.00 54.98  ? 463 ILE B O   1 
ATOM   7898  C CB  . ILE B 1 463 ? 93.740  134.334 137.069 1.00 54.84  ? 463 ILE B CB  1 
ATOM   7899  C CG1 . ILE B 1 463 ? 94.186  134.901 138.430 1.00 53.67  ? 463 ILE B CG1 1 
ATOM   7900  C CG2 . ILE B 1 463 ? 93.410  132.838 137.168 1.00 54.74  ? 463 ILE B CG2 1 
ATOM   7901  C CD1 . ILE B 1 463 ? 93.053  135.018 139.452 1.00 54.57  ? 463 ILE B CD1 1 
ATOM   7902  N N   . TRP B 1 464 ? 96.302  132.720 135.717 1.00 60.40  ? 464 TRP B N   1 
ATOM   7903  C CA  . TRP B 1 464 ? 97.534  131.930 135.836 1.00 58.36  ? 464 TRP B CA  1 
ATOM   7904  C C   . TRP B 1 464 ? 98.764  132.539 135.142 1.00 60.81  ? 464 TRP B C   1 
ATOM   7905  O O   . TRP B 1 464 ? 99.890  132.127 135.417 1.00 61.27  ? 464 TRP B O   1 
ATOM   7906  C CB  . TRP B 1 464 ? 97.268  130.540 135.268 1.00 55.43  ? 464 TRP B CB  1 
ATOM   7907  N N   . ILE B 1 465 ? 98.563  133.528 134.266 1.00 62.50  ? 465 ILE B N   1 
ATOM   7908  C CA  . ILE B 1 465 ? 99.631  134.333 133.657 1.00 61.57  ? 465 ILE B CA  1 
ATOM   7909  C C   . ILE B 1 465 ? 99.640  135.797 134.136 1.00 59.78  ? 465 ILE B C   1 
ATOM   7910  O O   . ILE B 1 465 ? 100.675 136.449 134.086 1.00 60.51  ? 465 ILE B O   1 
ATOM   7911  C CB  . ILE B 1 465 ? 99.629  134.174 132.119 1.00 60.68  ? 465 ILE B CB  1 
ATOM   7912  C CG1 . ILE B 1 465 ? 98.371  134.724 131.431 1.00 58.73  ? 465 ILE B CG1 1 
ATOM   7913  C CG2 . ILE B 1 465 ? 99.893  132.702 131.762 1.00 59.27  ? 465 ILE B CG2 1 
ATOM   7914  C CD1 . ILE B 1 465 ? 98.475  134.738 129.908 1.00 49.76  ? 465 ILE B CD1 1 
ATOM   7915  N N   . SER B 1 466 ? 98.550  136.308 134.719 1.00 57.90  ? 466 SER B N   1 
ATOM   7916  C CA  . SER B 1 466 ? 98.445  137.674 135.270 1.00 60.94  ? 466 SER B CA  1 
ATOM   7917  C C   . SER B 1 466 ? 99.445  138.018 136.394 1.00 61.67  ? 466 SER B C   1 
ATOM   7918  O O   . SER B 1 466 ? 99.602  139.195 136.738 1.00 58.77  ? 466 SER B O   1 
ATOM   7919  C CB  . SER B 1 466 ? 97.034  137.903 135.808 1.00 59.24  ? 466 SER B CB  1 
ATOM   7920  O OG  . SER B 1 466 ? 96.845  137.245 137.046 1.00 59.01  ? 466 SER B OG  1 
ATOM   7921  N N   . PHE B 1 467 ? 100.108 137.008 136.964 1.00 64.14  ? 467 PHE B N   1 
ATOM   7922  C CA  . PHE B 1 467 ? 101.129 137.122 138.008 1.00 63.38  ? 467 PHE B CA  1 
ATOM   7923  C C   . PHE B 1 467 ? 102.502 136.535 137.607 1.00 64.85  ? 467 PHE B C   1 
ATOM   7924  O O   . PHE B 1 467 ? 103.407 136.504 138.437 1.00 66.48  ? 467 PHE B O   1 
ATOM   7925  C CB  . PHE B 1 467 ? 100.588 136.516 139.307 1.00 61.77  ? 467 PHE B CB  1 
ATOM   7926  C CG  . PHE B 1 467 ? 100.187 135.056 139.244 1.00 63.94  ? 467 PHE B CG  1 
ATOM   7927  C CD1 . PHE B 1 467 ? 101.167 134.047 139.245 1.00 65.46  ? 467 PHE B CD1 1 
ATOM   7928  C CD2 . PHE B 1 467 ? 98.828  134.697 139.275 1.00 61.80  ? 467 PHE B CD2 1 
ATOM   7929  C CE1 . PHE B 1 467 ? 100.791 132.695 139.274 1.00 65.01  ? 467 PHE B CE1 1 
ATOM   7930  C CE2 . PHE B 1 467 ? 98.451  133.349 139.315 1.00 63.57  ? 467 PHE B CE2 1 
ATOM   7931  C CZ  . PHE B 1 467 ? 99.431  132.345 139.311 1.00 62.69  ? 467 PHE B CZ  1 
ATOM   7932  N N   . MET B 1 468 ? 102.695 136.031 136.381 1.00 63.70  ? 468 MET B N   1 
ATOM   7933  C CA  . MET B 1 468 ? 103.873 135.203 136.055 1.00 64.67  ? 468 MET B CA  1 
ATOM   7934  C C   . MET B 1 468 ? 105.200 135.980 136.060 1.00 67.25  ? 468 MET B C   1 
ATOM   7935  O O   . MET B 1 468 ? 106.187 135.511 136.618 1.00 65.80  ? 468 MET B O   1 
ATOM   7936  C CB  . MET B 1 468 ? 103.651 134.458 134.729 1.00 65.54  ? 468 MET B CB  1 
ATOM   7937  C CG  . MET B 1 468 ? 103.710 135.334 133.479 1.00 66.00  ? 468 MET B CG  1 
ATOM   7938  S SD  . MET B 1 468 ? 103.150 134.493 131.981 1.00 77.49  ? 468 MET B SD  1 
ATOM   7939  C CE  . MET B 1 468 ? 102.906 135.944 130.933 1.00 61.89  ? 468 MET B CE  1 
ATOM   7940  N N   . ASP B 1 469 ? 105.212 137.192 135.498 1.00 60.77  ? 469 ASP B N   1 
ATOM   7941  C CA  . ASP B 1 469 ? 106.315 138.167 135.577 1.00 58.04  ? 469 ASP B CA  1 
ATOM   7942  C C   . ASP B 1 469 ? 105.964 139.345 136.506 1.00 52.71  ? 469 ASP B C   1 
ATOM   7943  O O   . ASP B 1 469 ? 106.703 140.326 136.606 1.00 53.60  ? 469 ASP B O   1 
ATOM   7944  C CB  . ASP B 1 469 ? 106.721 138.631 134.167 1.00 57.92  ? 469 ASP B CB  1 
ATOM   7945  C CG  . ASP B 1 469 ? 105.616 139.324 133.362 1.00 56.12  ? 469 ASP B CG  1 
ATOM   7946  O OD1 . ASP B 1 469 ? 104.475 139.452 133.847 1.00 57.25  ? 469 ASP B OD1 1 
ATOM   7947  O OD2 . ASP B 1 469 ? 105.891 139.710 132.209 1.00 59.63  ? 469 ASP B OD2 1 
ATOM   7948  N N   . SER B 1 470 ? 104.862 139.209 137.238 1.00 49.46  ? 470 SER B N   1 
ATOM   7949  C CA  . SER B 1 470 ? 104.138 140.221 138.013 1.00 49.45  ? 470 SER B CA  1 
ATOM   7950  C C   . SER B 1 470 ? 103.678 139.658 139.368 1.00 47.94  ? 470 SER B C   1 
ATOM   7951  O O   . SER B 1 470 ? 102.571 139.908 139.839 1.00 48.78  ? 470 SER B O   1 
ATOM   7952  C CB  . SER B 1 470 ? 102.975 140.739 137.163 1.00 49.69  ? 470 SER B CB  1 
ATOM   7953  O OG  . SER B 1 470 ? 102.257 139.635 136.661 1.00 54.89  ? 470 SER B OG  1 
ATOM   7954  N N   . TYR B 1 471 ? 104.551 138.886 140.024 1.00 39.18  ? 471 TYR B N   1 
ATOM   7955  C CA  . TYR B 1 471 ? 104.307 138.310 141.348 1.00 36.55  ? 471 TYR B CA  1 
ATOM   7956  C C   . TYR B 1 471 ? 104.110 139.365 142.442 1.00 32.12  ? 471 TYR B C   1 
ATOM   7957  O O   . TYR B 1 471 ? 103.579 139.049 143.497 1.00 37.34  ? 471 TYR B O   1 
ATOM   7958  C CB  . TYR B 1 471 ? 105.447 137.343 141.713 1.00 42.33  ? 471 TYR B CB  1 
ATOM   7959  C CG  . TYR B 1 471 ? 106.809 137.981 141.915 1.00 41.07  ? 471 TYR B CG  1 
ATOM   7960  C CD1 . TYR B 1 471 ? 107.007 138.890 142.971 1.00 40.91  ? 471 TYR B CD1 1 
ATOM   7961  C CD2 . TYR B 1 471 ? 107.890 137.650 141.081 1.00 44.05  ? 471 TYR B CD2 1 
ATOM   7962  C CE1 . TYR B 1 471 ? 108.224 139.557 143.130 1.00 39.87  ? 471 TYR B CE1 1 
ATOM   7963  C CE2 . TYR B 1 471 ? 109.146 138.256 141.292 1.00 46.66  ? 471 TYR B CE2 1 
ATOM   7964  C CZ  . TYR B 1 471 ? 109.303 139.239 142.295 1.00 45.92  ? 471 TYR B CZ  1 
ATOM   7965  O OH  . TYR B 1 471 ? 110.498 139.822 142.520 1.00 41.70  ? 471 TYR B OH  1 
ATOM   7966  N N   . PHE B 1 472 ? 104.494 140.627 142.230 1.00 29.54  ? 472 PHE B N   1 
ATOM   7967  C CA  . PHE B 1 472 ? 104.164 141.710 143.150 1.00 18.15  ? 472 PHE B CA  1 
ATOM   7968  C C   . PHE B 1 472 ? 102.661 141.887 143.319 1.00 18.77  ? 472 PHE B C   1 
ATOM   7969  O O   . PHE B 1 472 ? 102.238 142.322 144.376 1.00 37.88  ? 472 PHE B O   1 
ATOM   7970  C CB  . PHE B 1 472 ? 104.813 143.027 142.712 1.00 23.48  ? 472 PHE B CB  1 
ATOM   7971  C CG  . PHE B 1 472 ? 106.227 143.204 143.207 1.00 17.85  ? 472 PHE B CG  1 
ATOM   7972  C CD1 . PHE B 1 472 ? 106.461 143.298 144.588 1.00 20.34  ? 472 PHE B CD1 1 
ATOM   7973  C CD2 . PHE B 1 472 ? 107.299 143.306 142.307 1.00 21.46  ? 472 PHE B CD2 1 
ATOM   7974  C CE1 . PHE B 1 472 ? 107.764 143.467 145.070 1.00 17.43  ? 472 PHE B CE1 1 
ATOM   7975  C CE2 . PHE B 1 472 ? 108.600 143.506 142.792 1.00 19.70  ? 472 PHE B CE2 1 
ATOM   7976  C CZ  . PHE B 1 472 ? 108.827 143.585 144.173 1.00 22.00  ? 472 PHE B CZ  1 
ATOM   7977  N N   . GLU B 1 473 ? 101.822 141.496 142.367 1.00 28.40  ? 473 GLU B N   1 
ATOM   7978  C CA  . GLU B 1 473 ? 100.373 141.496 142.582 1.00 28.14  ? 473 GLU B CA  1 
ATOM   7979  C C   . GLU B 1 473 ? 99.950  140.420 143.603 1.00 29.94  ? 473 GLU B C   1 
ATOM   7980  O O   . GLU B 1 473 ? 99.064  140.631 144.421 1.00 34.40  ? 473 GLU B O   1 
ATOM   7981  C CB  . GLU B 1 473 ? 99.640  141.346 141.238 1.00 30.66  ? 473 GLU B CB  1 
ATOM   7982  C CG  . GLU B 1 473 ? 100.045 142.392 140.181 1.00 27.04  ? 473 GLU B CG  1 
ATOM   7983  C CD  . GLU B 1 473 ? 99.841  143.854 140.613 1.00 38.11  ? 473 GLU B CD  1 
ATOM   7984  O OE1 . GLU B 1 473 ? 98.740  144.240 141.051 1.00 39.24  ? 473 GLU B OE1 1 
ATOM   7985  O OE2 . GLU B 1 473 ? 100.814 144.642 140.521 1.00 47.14  ? 473 GLU B OE2 1 
ATOM   7986  N N   . ILE B 1 474 ? 100.635 139.276 143.658 1.00 34.79  ? 474 ILE B N   1 
ATOM   7987  C CA  . ILE B 1 474 ? 100.465 138.307 144.749 1.00 25.72  ? 474 ILE B CA  1 
ATOM   7988  C C   . ILE B 1 474 ? 101.021 138.869 146.066 1.00 27.11  ? 474 ILE B C   1 
ATOM   7989  O O   . ILE B 1 474 ? 100.351 138.786 147.088 1.00 37.13  ? 474 ILE B O   1 
ATOM   7990  C CB  . ILE B 1 474 ? 101.077 136.932 144.383 1.00 32.78  ? 474 ILE B CB  1 
ATOM   7991  C CG1 . ILE B 1 474 ? 100.262 136.307 143.235 1.00 32.02  ? 474 ILE B CG1 1 
ATOM   7992  C CG2 . ILE B 1 474 ? 101.112 135.991 145.601 1.00 28.37  ? 474 ILE B CG2 1 
ATOM   7993  C CD1 . ILE B 1 474 ? 100.793 134.973 142.712 1.00 36.89  ? 474 ILE B CD1 1 
ATOM   7994  N N   . LEU B 1 475 ? 102.219 139.460 146.075 1.00 25.68  ? 475 LEU B N   1 
ATOM   7995  C CA  . LEU B 1 475 ? 102.845 139.956 147.303 1.00 17.93  ? 475 LEU B CA  1 
ATOM   7996  C C   . LEU B 1 475 ? 102.127 141.167 147.915 1.00 19.70  ? 475 LEU B C   1 
ATOM   7997  O O   . LEU B 1 475 ? 102.026 141.254 149.136 1.00 30.74  ? 475 LEU B O   1 
ATOM   7998  C CB  . LEU B 1 475 ? 104.326 140.278 147.074 1.00 28.40  ? 475 LEU B CB  1 
ATOM   7999  C CG  . LEU B 1 475 ? 105.208 139.116 146.590 1.00 26.69  ? 475 LEU B CG  1 
ATOM   8000  C CD1 . LEU B 1 475 ? 106.623 139.627 146.366 1.00 29.50  ? 475 LEU B CD1 1 
ATOM   8001  C CD2 . LEU B 1 475 ? 105.268 137.942 147.557 1.00 17.91  ? 475 LEU B CD2 1 
ATOM   8002  N N   . PHE B 1 476 ? 101.584 142.087 147.116 1.00 13.50  ? 476 PHE B N   1 
ATOM   8003  C CA  . PHE B 1 476 ? 100.736 143.175 147.606 1.00 9.69   ? 476 PHE B CA  1 
ATOM   8004  C C   . PHE B 1 476 ? 99.398  142.660 148.146 1.00 11.47  ? 476 PHE B C   1 
ATOM   8005  O O   . PHE B 1 476 ? 98.964  143.133 149.191 1.00 22.61  ? 476 PHE B O   1 
ATOM   8006  C CB  . PHE B 1 476 ? 100.529 144.238 146.522 1.00 13.93  ? 476 PHE B CB  1 
ATOM   8007  C CG  . PHE B 1 476 ? 101.583 145.332 146.473 1.00 11.99  ? 476 PHE B CG  1 
ATOM   8008  C CD1 . PHE B 1 476 ? 102.838 145.113 145.883 1.00 13.79  ? 476 PHE B CD1 1 
ATOM   8009  C CD2 . PHE B 1 476 ? 101.291 146.600 147.003 1.00 9.56   ? 476 PHE B CD2 1 
ATOM   8010  C CE1 . PHE B 1 476 ? 103.770 146.154 145.780 1.00 10.13  ? 476 PHE B CE1 1 
ATOM   8011  C CE2 . PHE B 1 476 ? 102.226 147.639 146.910 1.00 13.54  ? 476 PHE B CE2 1 
ATOM   8012  C CZ  . PHE B 1 476 ? 103.462 147.420 146.289 1.00 9.53   ? 476 PHE B CZ  1 
ATOM   8013  N N   . LEU B 1 477 ? 98.772  141.660 147.511 1.00 24.46  ? 477 LEU B N   1 
ATOM   8014  C CA  . LEU B 1 477 ? 97.573  141.012 148.043 1.00 27.82  ? 477 LEU B CA  1 
ATOM   8015  C C   . LEU B 1 477 ? 97.842  140.316 149.382 1.00 22.59  ? 477 LEU B C   1 
ATOM   8016  O O   . LEU B 1 477 ? 97.102  140.515 150.341 1.00 31.90  ? 477 LEU B O   1 
ATOM   8017  C CB  . LEU B 1 477 ? 97.014  140.014 147.007 1.00 27.64  ? 477 LEU B CB  1 
ATOM   8018  C CG  . LEU B 1 477 ? 95.737  139.287 147.462 1.00 29.88  ? 477 LEU B CG  1 
ATOM   8019  C CD1 . LEU B 1 477 ? 94.537  140.216 147.503 1.00 27.58  ? 477 LEU B CD1 1 
ATOM   8020  C CD2 . LEU B 1 477 ? 95.417  138.137 146.522 1.00 29.74  ? 477 LEU B CD2 1 
ATOM   8021  N N   . LEU B 1 478 ? 98.917  139.530 149.469 1.00 25.68  ? 478 LEU B N   1 
ATOM   8022  C CA  . LEU B 1 478 ? 99.311  138.833 150.687 1.00 20.98  ? 478 LEU B CA  1 
ATOM   8023  C C   . LEU B 1 478 ? 99.624  139.806 151.828 1.00 18.21  ? 478 LEU B C   1 
ATOM   8024  O O   . LEU B 1 478 ? 99.163  139.598 152.945 1.00 31.35  ? 478 LEU B O   1 
ATOM   8025  C CB  . LEU B 1 478 ? 100.476 137.891 150.363 1.00 28.45  ? 478 LEU B CB  1 
ATOM   8026  C CG  . LEU B 1 478 ? 100.994 137.082 151.559 1.00 36.43  ? 478 LEU B CG  1 
ATOM   8027  C CD1 . LEU B 1 478 ? 99.946  136.131 152.118 1.00 27.98  ? 478 LEU B CD1 1 
ATOM   8028  C CD2 . LEU B 1 478 ? 102.222 136.286 151.142 1.00 27.32  ? 478 LEU B CD2 1 
ATOM   8029  N N   . GLN B 1 479 ? 100.332 140.907 151.572 1.00 17.57  ? 479 GLN B N   1 
ATOM   8030  C CA  . GLN B 1 479 ? 100.604 141.924 152.588 1.00 17.28  ? 479 GLN B CA  1 
ATOM   8031  C C   . GLN B 1 479 ? 99.328  142.558 153.133 1.00 20.46  ? 479 GLN B C   1 
ATOM   8032  O O   . GLN B 1 479 ? 99.187  142.725 154.340 1.00 28.93  ? 479 GLN B O   1 
ATOM   8033  C CB  . GLN B 1 479 ? 101.529 142.993 151.996 1.00 19.84  ? 479 GLN B CB  1 
ATOM   8034  C CG  . GLN B 1 479 ? 102.278 143.819 153.048 1.00 19.43  ? 479 GLN B CG  1 
ATOM   8035  C CD  . GLN B 1 479 ? 101.593 145.065 153.608 1.00 21.70  ? 479 GLN B CD  1 
ATOM   8036  O OE1 . GLN B 1 479 ? 100.648 145.620 153.074 1.00 23.79  ? 479 GLN B OE1 1 
ATOM   8037  N NE2 . GLN B 1 479 ? 102.102 145.585 154.696 1.00 30.31  ? 479 GLN B NE2 1 
ATOM   8038  N N   . ALA B 1 480 ? 98.371  142.870 152.263 1.00 28.61  ? 480 ALA B N   1 
ATOM   8039  C CA  . ALA B 1 480 ? 97.091  143.434 152.638 1.00 24.18  ? 480 ALA B CA  1 
ATOM   8040  C C   . ALA B 1 480 ? 96.228  142.445 153.442 1.00 24.10  ? 480 ALA B C   1 
ATOM   8041  O O   . ALA B 1 480 ? 95.673  142.820 154.470 1.00 27.06  ? 480 ALA B O   1 
ATOM   8042  C CB  . ALA B 1 480 ? 96.414  143.895 151.358 1.00 29.88  ? 480 ALA B CB  1 
ATOM   8043  N N   . LEU B 1 481 ? 96.174  141.165 153.050 1.00 24.01  ? 481 LEU B N   1 
ATOM   8044  C CA  . LEU B 1 481 ? 95.522  140.105 153.825 1.00 28.63  ? 481 LEU B CA  1 
ATOM   8045  C C   . LEU B 1 481 ? 96.127  139.955 155.225 1.00 29.78  ? 481 LEU B C   1 
ATOM   8046  O O   . LEU B 1 481 ? 95.402  140.036 156.212 1.00 33.93  ? 481 LEU B O   1 
ATOM   8047  C CB  . LEU B 1 481 ? 95.616  138.761 153.081 1.00 31.27  ? 481 LEU B CB  1 
ATOM   8048  C CG  . LEU B 1 481 ? 94.638  138.600 151.911 1.00 35.54  ? 481 LEU B CG  1 
ATOM   8049  C CD1 . LEU B 1 481 ? 94.971  137.326 151.141 1.00 35.61  ? 481 LEU B CD1 1 
ATOM   8050  C CD2 . LEU B 1 481 ? 93.195  138.490 152.399 1.00 31.02  ? 481 LEU B CD2 1 
ATOM   8051  N N   . LEU B 1 482 ? 97.445  139.776 155.327 1.00 33.85  ? 482 LEU B N   1 
ATOM   8052  C CA  . LEU B 1 482 ? 98.133  139.629 156.611 1.00 26.18  ? 482 LEU B CA  1 
ATOM   8053  C C   . LEU B 1 482 ? 97.979  140.878 157.486 1.00 19.12  ? 482 LEU B C   1 
ATOM   8054  O O   . LEU B 1 482 ? 97.838  140.762 158.700 1.00 32.65  ? 482 LEU B O   1 
ATOM   8055  C CB  . LEU B 1 482 ? 99.610  139.297 156.373 1.00 30.20  ? 482 LEU B CB  1 
ATOM   8056  C CG  . LEU B 1 482 ? 99.889  137.956 155.684 1.00 30.29  ? 482 LEU B CG  1 
ATOM   8057  C CD1 . LEU B 1 482 ? 101.376 137.879 155.357 1.00 28.26  ? 482 LEU B CD1 1 
ATOM   8058  C CD2 . LEU B 1 482 ? 99.528  136.763 156.555 1.00 29.62  ? 482 LEU B CD2 1 
ATOM   8059  N N   . THR B 1 483 ? 97.904  142.065 156.884 1.00 25.03  ? 483 THR B N   1 
ATOM   8060  C CA  . THR B 1 483 ? 97.609  143.305 157.600 1.00 25.83  ? 483 THR B CA  1 
ATOM   8061  C C   . THR B 1 483 ? 96.210  143.289 158.196 1.00 30.04  ? 483 THR B C   1 
ATOM   8062  O O   . THR B 1 483 ? 96.072  143.496 159.395 1.00 40.80  ? 483 THR B O   1 
ATOM   8063  C CB  . THR B 1 483 ? 97.767  144.528 156.698 1.00 27.38  ? 483 THR B CB  1 
ATOM   8064  O OG1 . THR B 1 483 ? 99.077  144.575 156.220 1.00 38.10  ? 483 THR B OG1 1 
ATOM   8065  C CG2 . THR B 1 483 ? 97.514  145.826 157.449 1.00 29.80  ? 483 THR B CG2 1 
ATOM   8066  N N   . VAL B 1 484 ? 95.172  142.997 157.411 1.00 40.82  ? 484 VAL B N   1 
ATOM   8067  C CA  . VAL B 1 484 ? 93.791  142.933 157.901 1.00 37.48  ? 484 VAL B CA  1 
ATOM   8068  C C   . VAL B 1 484 ? 93.634  141.830 158.947 1.00 37.25  ? 484 VAL B C   1 
ATOM   8069  O O   . VAL B 1 484 ? 93.112  142.094 160.025 1.00 46.32  ? 484 VAL B O   1 
ATOM   8070  C CB  . VAL B 1 484 ? 92.804  142.790 156.725 1.00 37.10  ? 484 VAL B CB  1 
ATOM   8071  C CG1 . VAL B 1 484 ? 91.363  142.576 157.186 1.00 39.12  ? 484 VAL B CG1 1 
ATOM   8072  C CG2 . VAL B 1 484 ? 92.820  144.060 155.876 1.00 37.14  ? 484 VAL B CG2 1 
ATOM   8073  N N   . LEU B 1 485 ? 94.179  140.637 158.712 1.00 38.90  ? 485 LEU B N   1 
ATOM   8074  C CA  . LEU B 1 485 ? 94.186  139.558 159.698 1.00 39.37  ? 485 LEU B CA  1 
ATOM   8075  C C   . LEU B 1 485 ? 94.891  139.966 160.995 1.00 41.24  ? 485 LEU B C   1 
ATOM   8076  O O   . LEU B 1 485 ? 94.354  139.716 162.065 1.00 44.83  ? 485 LEU B O   1 
ATOM   8077  C CB  . LEU B 1 485 ? 94.816  138.292 159.102 1.00 37.67  ? 485 LEU B CB  1 
ATOM   8078  C CG  . LEU B 1 485 ? 93.941  137.609 158.043 1.00 48.38  ? 485 LEU B CG  1 
ATOM   8079  C CD1 . LEU B 1 485 ? 94.760  136.561 157.296 1.00 45.48  ? 485 LEU B CD1 1 
ATOM   8080  C CD2 . LEU B 1 485 ? 92.726  136.930 158.672 1.00 46.90  ? 485 LEU B CD2 1 
ATOM   8081  N N   . SER B 1 486 ? 96.033  140.653 160.943 1.00 40.41  ? 486 SER B N   1 
ATOM   8082  C CA  . SER B 1 486 ? 96.704  141.129 162.160 1.00 34.06  ? 486 SER B CA  1 
ATOM   8083  C C   . SER B 1 486 ? 95.829  142.086 162.972 1.00 40.08  ? 486 SER B C   1 
ATOM   8084  O O   . SER B 1 486 ? 95.811  142.000 164.192 1.00 47.40  ? 486 SER B O   1 
ATOM   8085  C CB  . SER B 1 486 ? 98.055  141.770 161.843 1.00 34.81  ? 486 SER B CB  1 
ATOM   8086  O OG  . SER B 1 486 ? 97.923  143.056 161.287 1.00 41.13  ? 486 SER B OG  1 
ATOM   8087  N N   . GLN B 1 487 ? 95.037  142.948 162.332 1.00 45.19  ? 487 GLN B N   1 
ATOM   8088  C CA  . GLN B 1 487 ? 94.114  143.846 163.029 1.00 44.12  ? 487 GLN B CA  1 
ATOM   8089  C C   . GLN B 1 487 ? 92.889  143.116 163.593 1.00 44.29  ? 487 GLN B C   1 
ATOM   8090  O O   . GLN B 1 487 ? 92.465  143.413 164.705 1.00 47.22  ? 487 GLN B O   1 
ATOM   8091  C CB  . GLN B 1 487 ? 93.694  144.986 162.097 1.00 44.22  ? 487 GLN B CB  1 
ATOM   8092  C CG  . GLN B 1 487 ? 94.879  145.838 161.626 1.00 43.31  ? 487 GLN B CG  1 
ATOM   8093  C CD  . GLN B 1 487 ? 95.739  146.352 162.769 1.00 45.13  ? 487 GLN B CD  1 
ATOM   8094  O OE1 . GLN B 1 487 ? 95.261  146.954 163.716 1.00 51.78  ? 487 GLN B OE1 1 
ATOM   8095  N NE2 . GLN B 1 487 ? 97.032  146.119 162.741 1.00 45.83  ? 487 GLN B NE2 1 
ATOM   8096  N N   . VAL B 1 488 ? 92.371  142.099 162.898 1.00 48.48  ? 488 VAL B N   1 
ATOM   8097  C CA  . VAL B 1 488 ? 91.326  141.207 163.424 1.00 49.13  ? 488 VAL B CA  1 
ATOM   8098  C C   . VAL B 1 488 ? 91.822  140.444 164.656 1.00 51.61  ? 488 VAL B C   1 
ATOM   8099  O O   . VAL B 1 488 ? 91.169  140.467 165.696 1.00 53.86  ? 488 VAL B O   1 
ATOM   8100  C CB  . VAL B 1 488 ? 90.837  140.245 162.323 1.00 48.60  ? 488 VAL B CB  1 
ATOM   8101  C CG1 . VAL B 1 488 ? 89.893  139.165 162.852 1.00 50.61  ? 488 VAL B CG1 1 
ATOM   8102  C CG2 . VAL B 1 488 ? 90.091  141.017 161.231 1.00 45.73  ? 488 VAL B CG2 1 
ATOM   8103  N N   . LEU B 1 489 ? 93.008  139.832 164.598 1.00 49.63  ? 489 LEU B N   1 
ATOM   8104  C CA  . LEU B 1 489 ? 93.598  139.141 165.747 1.00 44.98  ? 489 LEU B CA  1 
ATOM   8105  C C   . LEU B 1 489 ? 93.898  140.098 166.909 1.00 44.76  ? 489 LEU B C   1 
ATOM   8106  O O   . LEU B 1 489 ? 93.724  139.723 168.066 1.00 53.42  ? 489 LEU B O   1 
ATOM   8107  C CB  . LEU B 1 489 ? 94.872  138.391 165.324 1.00 48.57  ? 489 LEU B CB  1 
ATOM   8108  C CG  . LEU B 1 489 ? 94.705  137.213 164.350 1.00 47.46  ? 489 LEU B CG  1 
ATOM   8109  C CD1 . LEU B 1 489 ? 95.937  136.317 164.457 1.00 45.55  ? 489 LEU B CD1 1 
ATOM   8110  C CD2 . LEU B 1 489 ? 93.478  136.343 164.617 1.00 47.28  ? 489 LEU B CD2 1 
ATOM   8111  N N   . ARG B 1 490 ? 94.292  141.343 166.629 1.00 42.08  ? 490 ARG B N   1 
ATOM   8112  C CA  . ARG B 1 490 ? 94.487  142.384 167.645 1.00 47.42  ? 490 ARG B CA  1 
ATOM   8113  C C   . ARG B 1 490 ? 93.176  142.762 168.340 1.00 52.44  ? 490 ARG B C   1 
ATOM   8114  O O   . ARG B 1 490 ? 93.164  142.897 169.559 1.00 58.06  ? 490 ARG B O   1 
ATOM   8115  C CB  . ARG B 1 490 ? 95.161  143.589 166.984 1.00 49.96  ? 490 ARG B CB  1 
ATOM   8116  C CG  . ARG B 1 490 ? 95.553  144.660 167.995 1.00 44.81  ? 490 ARG B CG  1 
ATOM   8117  C CD  . ARG B 1 490 ? 96.113  145.881 167.272 1.00 50.55  ? 490 ARG B CD  1 
ATOM   8118  N NE  . ARG B 1 490 ? 96.220  147.029 168.187 1.00 57.82  ? 490 ARG B NE  1 
ATOM   8119  C CZ  . ARG B 1 490 ? 95.262  147.862 168.543 1.00 54.27  ? 490 ARG B CZ  1 
ATOM   8120  N NH1 . ARG B 1 490 ? 95.490  148.796 169.412 1.00 53.12  ? 490 ARG B NH1 1 
ATOM   8121  N NH2 . ARG B 1 490 ? 94.062  147.783 168.066 1.00 49.85  ? 490 ARG B NH2 1 
ATOM   8122  N N   . PHE B 1 491 ? 92.060  142.874 167.614 1.00 57.86  ? 491 PHE B N   1 
ATOM   8123  C CA  . PHE B 1 491 ? 90.733  143.068 168.225 1.00 57.35  ? 491 PHE B CA  1 
ATOM   8124  C C   . PHE B 1 491 ? 90.272  141.853 169.054 1.00 60.68  ? 491 PHE B C   1 
ATOM   8125  O O   . PHE B 1 491 ? 89.663  142.030 170.107 1.00 62.21  ? 491 PHE B O   1 
ATOM   8126  C CB  . PHE B 1 491 ? 89.694  143.401 167.146 1.00 56.81  ? 491 PHE B CB  1 
ATOM   8127  C CG  . PHE B 1 491 ? 89.921  144.664 166.330 1.00 60.54  ? 491 PHE B CG  1 
ATOM   8128  C CD1 . PHE B 1 491 ? 90.512  145.812 166.893 1.00 60.16  ? 491 PHE B CD1 1 
ATOM   8129  C CD2 . PHE B 1 491 ? 89.474  144.708 164.992 1.00 60.86  ? 491 PHE B CD2 1 
ATOM   8130  C CE1 . PHE B 1 491 ? 90.663  146.980 166.127 1.00 58.92  ? 491 PHE B CE1 1 
ATOM   8131  C CE2 . PHE B 1 491 ? 89.632  145.875 164.226 1.00 60.13  ? 491 PHE B CE2 1 
ATOM   8132  C CZ  . PHE B 1 491 ? 90.222  147.015 164.795 1.00 60.90  ? 491 PHE B CZ  1 
ATOM   8133  N N   . MET B 1 492 ? 90.611  140.629 168.643 1.00 59.42  ? 492 MET B N   1 
ATOM   8134  C CA  . MET B 1 492 ? 90.428  139.410 169.450 1.00 58.85  ? 492 MET B CA  1 
ATOM   8135  C C   . MET B 1 492 ? 91.395  139.292 170.645 1.00 60.65  ? 492 MET B C   1 
ATOM   8136  O O   . MET B 1 492 ? 91.266  138.369 171.446 1.00 63.29  ? 492 MET B O   1 
ATOM   8137  C CB  . MET B 1 492 ? 90.563  138.169 168.557 1.00 59.12  ? 492 MET B CB  1 
ATOM   8138  C CG  . MET B 1 492 ? 89.465  138.065 167.501 1.00 61.62  ? 492 MET B CG  1 
ATOM   8139  S SD  . MET B 1 492 ? 89.665  136.613 166.441 1.00 73.56  ? 492 MET B SD  1 
ATOM   8140  C CE  . MET B 1 492 ? 88.198  136.809 165.407 1.00 60.99  ? 492 MET B CE  1 
ATOM   8141  N N   . GLU B 1 493 ? 92.356  140.207 170.781 1.00 60.82  ? 493 GLU B N   1 
ATOM   8142  C CA  . GLU B 1 493 ? 93.390  140.225 171.818 1.00 61.95  ? 493 GLU B CA  1 
ATOM   8143  C C   . GLU B 1 493 ? 94.289  138.973 171.902 1.00 61.67  ? 493 GLU B C   1 
ATOM   8144  O O   . GLU B 1 493 ? 94.901  138.730 172.942 1.00 62.54  ? 493 GLU B O   1 
ATOM   8145  C CB  . GLU B 1 493 ? 92.750  140.588 173.157 1.00 59.14  ? 493 GLU B CB  1 
ATOM   8146  N N   . THR B 1 494 ? 94.398  138.166 170.840 1.00 56.06  ? 494 THR B N   1 
ATOM   8147  C CA  . THR B 1 494 ? 95.310  137.003 170.818 1.00 58.27  ? 494 THR B CA  1 
ATOM   8148  C C   . THR B 1 494 ? 96.754  137.425 170.543 1.00 56.70  ? 494 THR B C   1 
ATOM   8149  O O   . THR B 1 494 ? 96.992  138.340 169.759 1.00 59.02  ? 494 THR B O   1 
ATOM   8150  C CB  . THR B 1 494 ? 94.831  135.913 169.847 1.00 57.68  ? 494 THR B CB  1 
ATOM   8151  O OG1 . THR B 1 494 ? 95.636  134.766 169.975 1.00 58.53  ? 494 THR B OG1 1 
ATOM   8152  C CG2 . THR B 1 494 ? 94.878  136.292 168.372 1.00 54.73  ? 494 THR B CG2 1 
ATOM   8153  N N   . GLU B 1 495 ? 97.749  136.772 171.151 1.00 57.16  ? 495 GLU B N   1 
ATOM   8154  C CA  . GLU B 1 495 ? 99.167  137.145 171.002 1.00 56.33  ? 495 GLU B CA  1 
ATOM   8155  C C   . GLU B 1 495 ? 99.680  137.045 169.555 1.00 56.47  ? 495 GLU B C   1 
ATOM   8156  O O   . GLU B 1 495 ? 100.563 137.797 169.145 1.00 59.53  ? 495 GLU B O   1 
ATOM   8157  C CB  . GLU B 1 495 ? 100.028 136.293 171.948 1.00 57.57  ? 495 GLU B CB  1 
ATOM   8158  C CG  . GLU B 1 495 ? 100.151 134.816 171.531 1.00 58.05  ? 495 GLU B CG  1 
ATOM   8159  C CD  . GLU B 1 495 ? 100.957 133.980 172.534 1.00 60.80  ? 495 GLU B CD  1 
ATOM   8160  O OE1 . GLU B 1 495 ? 101.954 134.473 173.100 1.00 58.61  ? 495 GLU B OE1 1 
ATOM   8161  O OE2 . GLU B 1 495 ? 100.609 132.803 172.770 1.00 62.34  ? 495 GLU B OE2 1 
ATOM   8162  N N   . TRP B 1 496 ? 99.093  136.157 168.754 1.00 48.41  ? 496 TRP B N   1 
ATOM   8163  C CA  . TRP B 1 496 ? 99.494  135.884 167.376 1.00 47.81  ? 496 TRP B CA  1 
ATOM   8164  C C   . TRP B 1 496 ? 99.243  137.036 166.401 1.00 50.21  ? 496 TRP B C   1 
ATOM   8165  O O   . TRP B 1 496 ? 99.684  136.973 165.255 1.00 51.33  ? 496 TRP B O   1 
ATOM   8166  C CB  . TRP B 1 496 ? 98.845  134.572 166.923 1.00 48.86  ? 496 TRP B CB  1 
ATOM   8167  C CG  . TRP B 1 496 ? 99.343  133.419 167.729 1.00 54.42  ? 496 TRP B CG  1 
ATOM   8168  C CD1 . TRP B 1 496 ? 98.693  132.829 168.757 1.00 52.13  ? 496 TRP B CD1 1 
ATOM   8169  C CD2 . TRP B 1 496 ? 100.668 132.811 167.686 1.00 57.48  ? 496 TRP B CD2 1 
ATOM   8170  N NE1 . TRP B 1 496 ? 99.538  131.926 169.372 1.00 52.46  ? 496 TRP B NE1 1 
ATOM   8171  C CE2 . TRP B 1 496 ? 100.779 131.900 168.774 1.00 56.74  ? 496 TRP B CE2 1 
ATOM   8172  C CE3 . TRP B 1 496 ? 101.801 132.970 166.858 1.00 51.11  ? 496 TRP B CE3 1 
ATOM   8173  C CZ2 . TRP B 1 496 ? 101.965 131.211 169.052 1.00 53.74  ? 496 TRP B CZ2 1 
ATOM   8174  C CZ3 . TRP B 1 496 ? 102.998 132.283 167.126 1.00 52.30  ? 496 TRP B CZ3 1 
ATOM   8175  C CH2 . TRP B 1 496 ? 103.084 131.414 168.229 1.00 53.97  ? 496 TRP B CH2 1 
ATOM   8176  N N   . TYR B 1 497 ? 98.601  138.121 166.838 1.00 44.51  ? 497 TYR B N   1 
ATOM   8177  C CA  . TYR B 1 497 ? 98.533  139.336 166.038 1.00 41.00  ? 497 TYR B CA  1 
ATOM   8178  C C   . TYR B 1 497 ? 99.928  139.906 165.744 1.00 41.34  ? 497 TYR B C   1 
ATOM   8179  O O   . TYR B 1 497 ? 100.150 140.398 164.641 1.00 44.27  ? 497 TYR B O   1 
ATOM   8180  C CB  . TYR B 1 497 ? 97.620  140.364 166.720 1.00 40.74  ? 497 TYR B CB  1 
ATOM   8181  C CG  . TYR B 1 497 ? 98.323  141.431 167.525 1.00 38.88  ? 497 TYR B CG  1 
ATOM   8182  C CD1 . TYR B 1 497 ? 98.766  142.615 166.902 1.00 40.78  ? 497 TYR B CD1 1 
ATOM   8183  C CD2 . TYR B 1 497 ? 98.579  141.217 168.885 1.00 39.73  ? 497 TYR B CD2 1 
ATOM   8184  C CE1 . TYR B 1 497 ? 99.481  143.576 167.642 1.00 38.91  ? 497 TYR B CE1 1 
ATOM   8185  C CE2 . TYR B 1 497 ? 99.286  142.171 169.626 1.00 44.05  ? 497 TYR B CE2 1 
ATOM   8186  C CZ  . TYR B 1 497 ? 99.747  143.346 169.008 1.00 45.76  ? 497 TYR B CZ  1 
ATOM   8187  O OH  . TYR B 1 497 ? 100.437 144.250 169.741 1.00 48.24  ? 497 TYR B OH  1 
ATOM   8188  N N   . LEU B 1 498 ? 100.876 139.814 166.684 1.00 35.89  ? 498 LEU B N   1 
ATOM   8189  C CA  . LEU B 1 498 ? 102.179 140.463 166.555 1.00 32.29  ? 498 LEU B CA  1 
ATOM   8190  C C   . LEU B 1 498 ? 103.083 139.796 165.498 1.00 34.76  ? 498 LEU B C   1 
ATOM   8191  O O   . LEU B 1 498 ? 103.586 140.513 164.638 1.00 33.51  ? 498 LEU B O   1 
ATOM   8192  C CB  . LEU B 1 498 ? 102.822 140.650 167.943 1.00 34.90  ? 498 LEU B CB  1 
ATOM   8193  C CG  . LEU B 1 498 ? 104.142 141.436 167.913 1.00 36.78  ? 498 LEU B CG  1 
ATOM   8194  C CD1 . LEU B 1 498 ? 103.918 142.898 167.542 1.00 35.26  ? 498 LEU B CD1 1 
ATOM   8195  C CD2 . LEU B 1 498 ? 104.819 141.389 169.276 1.00 34.72  ? 498 LEU B CD2 1 
ATOM   8196  N N   . PRO B 1 499 ? 103.236 138.461 165.441 1.00 34.18  ? 499 PRO B N   1 
ATOM   8197  C CA  . PRO B 1 499 ? 103.825 137.776 164.291 1.00 30.00  ? 499 PRO B CA  1 
ATOM   8198  C C   . PRO B 1 499 ? 103.196 138.126 162.936 1.00 32.61  ? 499 PRO B C   1 
ATOM   8199  O O   . PRO B 1 499 ? 103.932 138.333 161.977 1.00 34.63  ? 499 PRO B O   1 
ATOM   8200  C CB  . PRO B 1 499 ? 103.670 136.286 164.593 1.00 31.86  ? 499 PRO B CB  1 
ATOM   8201  C CG  . PRO B 1 499 ? 103.740 136.243 166.107 1.00 28.66  ? 499 PRO B CG  1 
ATOM   8202  C CD  . PRO B 1 499 ? 103.030 137.518 166.526 1.00 26.88  ? 499 PRO B CD  1 
ATOM   8203  N N   . LEU B 1 500 ? 101.865 138.247 162.826 1.00 31.27  ? 500 LEU B N   1 
ATOM   8204  C CA  . LEU B 1 500 ? 101.220 138.657 161.571 1.00 28.70  ? 500 LEU B CA  1 
ATOM   8205  C C   . LEU B 1 500 ? 101.500 140.118 161.214 1.00 28.93  ? 500 LEU B C   1 
ATOM   8206  O O   . LEU B 1 500 ? 101.767 140.414 160.053 1.00 35.11  ? 500 LEU B O   1 
ATOM   8207  C CB  . LEU B 1 500 ? 99.699  138.436 161.611 1.00 34.27  ? 500 LEU B CB  1 
ATOM   8208  C CG  . LEU B 1 500 ? 99.206  136.988 161.695 1.00 37.55  ? 500 LEU B CG  1 
ATOM   8209  C CD1 . LEU B 1 500 ? 97.698  136.996 161.452 1.00 38.08  ? 500 LEU B CD1 1 
ATOM   8210  C CD2 . LEU B 1 500 ? 99.835  136.082 160.646 1.00 33.87  ? 500 LEU B CD2 1 
ATOM   8211  N N   . LEU B 1 501 ? 101.471 141.033 162.181 1.00 20.11  ? 501 LEU B N   1 
ATOM   8212  C CA  . LEU B 1 501 ? 101.806 142.440 161.973 1.00 22.94  ? 501 LEU B CA  1 
ATOM   8213  C C   . LEU B 1 501 ? 103.256 142.596 161.508 1.00 22.34  ? 501 LEU B C   1 
ATOM   8214  O O   . LEU B 1 501 ? 103.539 143.328 160.566 1.00 31.03  ? 501 LEU B O   1 
ATOM   8215  C CB  . LEU B 1 501 ? 101.552 143.207 163.282 1.00 23.64  ? 501 LEU B CB  1 
ATOM   8216  C CG  . LEU B 1 501 ? 101.771 144.724 163.167 1.00 24.14  ? 501 LEU B CG  1 
ATOM   8217  C CD1 . LEU B 1 501 ? 100.598 145.384 162.449 1.00 26.78  ? 501 LEU B CD1 1 
ATOM   8218  C CD2 . LEU B 1 501 ? 101.906 145.349 164.546 1.00 27.36  ? 501 LEU B CD2 1 
ATOM   8219  N N   . VAL B 1 502 ? 104.175 141.871 162.129 1.00 32.50  ? 502 VAL B N   1 
ATOM   8220  C CA  . VAL B 1 502 ? 105.601 141.872 161.800 1.00 26.40  ? 502 VAL B CA  1 
ATOM   8221  C C   . VAL B 1 502 ? 105.884 141.200 160.451 1.00 22.48  ? 502 VAL B C   1 
ATOM   8222  O O   . VAL B 1 502 ? 106.675 141.723 159.676 1.00 33.73  ? 502 VAL B O   1 
ATOM   8223  C CB  . VAL B 1 502 ? 106.383 141.258 162.975 1.00 27.86  ? 502 VAL B CB  1 
ATOM   8224  C CG1 . VAL B 1 502 ? 107.837 140.997 162.635 1.00 25.75  ? 502 VAL B CG1 1 
ATOM   8225  C CG2 . VAL B 1 502 ? 106.371 142.231 164.159 1.00 19.38  ? 502 VAL B CG2 1 
ATOM   8226  N N   . LEU B 1 503 ? 105.204 140.112 160.093 1.00 17.67  ? 503 LEU B N   1 
ATOM   8227  C CA  . LEU B 1 503 ? 105.319 139.518 158.758 1.00 22.29  ? 503 LEU B CA  1 
ATOM   8228  C C   . LEU B 1 503 ? 104.771 140.453 157.665 1.00 24.64  ? 503 LEU B C   1 
ATOM   8229  O O   . LEU B 1 503 ? 105.379 140.595 156.608 1.00 33.37  ? 503 LEU B O   1 
ATOM   8230  C CB  . LEU B 1 503 ? 104.635 138.140 158.757 1.00 29.73  ? 503 LEU B CB  1 
ATOM   8231  C CG  . LEU B 1 503 ? 104.691 137.403 157.405 1.00 33.12  ? 503 LEU B CG  1 
ATOM   8232  C CD1 . LEU B 1 503 ? 106.113 137.128 156.928 1.00 31.91  ? 503 LEU B CD1 1 
ATOM   8233  C CD2 . LEU B 1 503 ? 103.952 136.075 157.514 1.00 27.39  ? 503 LEU B CD2 1 
ATOM   8234  N N   . SER B 1 504 ? 103.671 141.156 157.936 1.00 26.84  ? 504 SER B N   1 
ATOM   8235  C CA  . SER B 1 504 ? 103.116 142.194 157.060 1.00 18.01  ? 504 SER B CA  1 
ATOM   8236  C C   . SER B 1 504 ? 104.052 143.381 156.891 1.00 18.47  ? 504 SER B C   1 
ATOM   8237  O O   . SER B 1 504 ? 104.135 143.938 155.805 1.00 27.40  ? 504 SER B O   1 
ATOM   8238  C CB  . SER B 1 504 ? 101.815 142.748 157.634 1.00 22.38  ? 504 SER B CB  1 
ATOM   8239  O OG  . SER B 1 504 ? 100.916 141.718 157.908 1.00 35.72  ? 504 SER B OG  1 
ATOM   8240  N N   . LEU B 1 505 ? 104.762 143.782 157.941 1.00 18.08  ? 505 LEU B N   1 
ATOM   8241  C CA  . LEU B 1 505 ? 105.759 144.842 157.913 1.00 20.29  ? 505 LEU B CA  1 
ATOM   8242  C C   . LEU B 1 505 ? 106.954 144.482 157.020 1.00 18.80  ? 505 LEU B C   1 
ATOM   8243  O O   . LEU B 1 505 ? 107.308 145.265 156.145 1.00 26.87  ? 505 LEU B O   1 
ATOM   8244  C CB  . LEU B 1 505 ? 106.175 145.125 159.364 1.00 23.03  ? 505 LEU B CB  1 
ATOM   8245  C CG  . LEU B 1 505 ? 107.299 146.145 159.559 1.00 21.68  ? 505 LEU B CG  1 
ATOM   8246  C CD1 . LEU B 1 505 ? 106.820 147.559 159.279 1.00 15.78  ? 505 LEU B CD1 1 
ATOM   8247  C CD2 . LEU B 1 505 ? 107.783 146.059 161.000 1.00 18.06  ? 505 LEU B CD2 1 
ATOM   8248  N N   . VAL B 1 506 ? 107.546 143.297 157.190 1.00 19.36  ? 506 VAL B N   1 
ATOM   8249  C CA  . VAL B 1 506 ? 108.654 142.828 156.345 1.00 21.50  ? 506 VAL B CA  1 
ATOM   8250  C C   . VAL B 1 506 ? 108.209 142.759 154.891 1.00 18.10  ? 506 VAL B C   1 
ATOM   8251  O O   . VAL B 1 506 ? 108.837 143.349 154.018 1.00 22.74  ? 506 VAL B O   1 
ATOM   8252  C CB  . VAL B 1 506 ? 109.183 141.455 156.798 1.00 17.91  ? 506 VAL B CB  1 
ATOM   8253  C CG1 . VAL B 1 506 ? 110.253 140.896 155.861 1.00 21.90  ? 506 VAL B CG1 1 
ATOM   8254  C CG2 . VAL B 1 506 ? 109.817 141.536 158.174 1.00 18.27  ? 506 VAL B CG2 1 
ATOM   8255  N N   . LEU B 1 507 ? 107.082 142.096 154.632 1.00 17.51  ? 507 LEU B N   1 
ATOM   8256  C CA  . LEU B 1 507 ? 106.536 141.952 153.295 1.00 13.80  ? 507 LEU B CA  1 
ATOM   8257  C C   . LEU B 1 507 ? 106.197 143.306 152.653 1.00 8.21   ? 507 LEU B C   1 
ATOM   8258  O O   . LEU B 1 507 ? 106.424 143.496 151.470 1.00 30.62  ? 507 LEU B O   1 
ATOM   8259  C CB  . LEU B 1 507 ? 105.345 140.997 153.399 1.00 22.46  ? 507 LEU B CB  1 
ATOM   8260  C CG  . LEU B 1 507 ? 104.712 140.606 152.064 1.00 28.93  ? 507 LEU B CG  1 
ATOM   8261  C CD1 . LEU B 1 507 ? 105.689 139.944 151.105 1.00 28.20  ? 507 LEU B CD1 1 
ATOM   8262  C CD2 . LEU B 1 507 ? 103.584 139.624 152.335 1.00 27.25  ? 507 LEU B CD2 1 
ATOM   8263  N N   . GLY B 1 508 ? 105.752 144.290 153.433 1.00 7.75   ? 508 GLY B N   1 
ATOM   8264  C CA  . GLY B 1 508 ? 105.523 145.652 152.970 1.00 0.00   ? 508 GLY B CA  1 
ATOM   8265  C C   . GLY B 1 508 ? 106.781 146.433 152.603 1.00 9.08   ? 508 GLY B C   1 
ATOM   8266  O O   . GLY B 1 508 ? 106.760 147.203 151.650 1.00 22.83  ? 508 GLY B O   1 
ATOM   8267  N N   . TRP B 1 509 ? 107.914 146.224 153.267 1.00 22.55  ? 509 TRP B N   1 
ATOM   8268  C CA  . TRP B 1 509 ? 109.186 146.815 152.840 1.00 10.17  ? 509 TRP B CA  1 
ATOM   8269  C C   . TRP B 1 509 ? 109.736 146.168 151.568 1.00 10.41  ? 509 TRP B C   1 
ATOM   8270  O O   . TRP B 1 509 ? 110.213 146.869 150.691 1.00 23.34  ? 509 TRP B O   1 
ATOM   8271  C CB  . TRP B 1 509 ? 110.188 146.830 153.999 1.00 16.41  ? 509 TRP B CB  1 
ATOM   8272  C CG  . TRP B 1 509 ? 109.922 147.951 154.949 1.00 17.24  ? 509 TRP B CG  1 
ATOM   8273  C CD1 . TRP B 1 509 ? 109.361 147.853 156.171 1.00 16.52  ? 509 TRP B CD1 1 
ATOM   8274  C CD2 . TRP B 1 509 ? 110.118 149.380 154.720 1.00 26.27  ? 509 TRP B CD2 1 
ATOM   8275  N NE1 . TRP B 1 509 ? 109.155 149.117 156.680 1.00 17.42  ? 509 TRP B NE1 1 
ATOM   8276  C CE2 . TRP B 1 509 ? 109.559 150.096 155.813 1.00 23.38  ? 509 TRP B CE2 1 
ATOM   8277  C CE3 . TRP B 1 509 ? 110.698 150.150 153.687 1.00 28.04  ? 509 TRP B CE3 1 
ATOM   8278  C CZ2 . TRP B 1 509 ? 109.506 151.497 155.852 1.00 18.55  ? 509 TRP B CZ2 1 
ATOM   8279  C CZ3 . TRP B 1 509 ? 110.659 151.557 153.722 1.00 28.77  ? 509 TRP B CZ3 1 
ATOM   8280  C CH2 . TRP B 1 509 ? 110.038 152.232 154.785 1.00 24.48  ? 509 TRP B CH2 1 
ATOM   8281  N N   . LEU B 1 510 ? 109.609 144.847 151.453 1.00 16.98  ? 510 LEU B N   1 
ATOM   8282  C CA  . LEU B 1 510 ? 109.949 144.111 150.242 1.00 15.45  ? 510 LEU B CA  1 
ATOM   8283  C C   . LEU B 1 510 ? 109.074 144.545 149.060 1.00 17.71  ? 510 LEU B C   1 
ATOM   8284  O O   . LEU B 1 510 ? 109.571 144.672 147.948 1.00 31.40  ? 510 LEU B O   1 
ATOM   8285  C CB  . LEU B 1 510 ? 109.846 142.604 150.515 1.00 25.60  ? 510 LEU B CB  1 
ATOM   8286  C CG  . LEU B 1 510 ? 110.803 142.074 151.596 1.00 21.98  ? 510 LEU B CG  1 
ATOM   8287  C CD1 . LEU B 1 510 ? 110.550 140.596 151.834 1.00 17.29  ? 510 LEU B CD1 1 
ATOM   8288  C CD2 . LEU B 1 510 ? 112.259 142.271 151.219 1.00 22.35  ? 510 LEU B CD2 1 
ATOM   8289  N N   . ASN B 1 511 ? 107.804 144.863 149.296 1.00 16.52  ? 511 ASN B N   1 
ATOM   8290  C CA  . ASN B 1 511 ? 106.898 145.419 148.297 1.00 4.47   ? 511 ASN B CA  1 
ATOM   8291  C C   . ASN B 1 511 ? 107.327 146.780 147.744 1.00 4.09   ? 511 ASN B C   1 
ATOM   8292  O O   . ASN B 1 511 ? 107.066 147.041 146.576 1.00 29.61  ? 511 ASN B O   1 
ATOM   8293  C CB  . ASN B 1 511 ? 105.486 145.485 148.874 1.00 9.82   ? 511 ASN B CB  1 
ATOM   8294  C CG  . ASN B 1 511 ? 104.770 144.155 148.899 1.00 11.41  ? 511 ASN B CG  1 
ATOM   8295  O OD1 . ASN B 1 511 ? 105.206 143.166 148.341 1.00 21.80  ? 511 ASN B OD1 1 
ATOM   8296  N ND2 . ASN B 1 511 ? 103.616 144.097 149.508 1.00 8.75   ? 511 ASN B ND2 1 
ATOM   8297  N N   . LEU B 1 512 ? 108.037 147.631 148.488 1.00 14.32  ? 512 LEU B N   1 
ATOM   8298  C CA  . LEU B 1 512 ? 108.565 148.890 147.940 1.00 7.02   ? 512 LEU B CA  1 
ATOM   8299  C C   . LEU B 1 512 ? 109.559 148.684 146.792 1.00 13.89  ? 512 LEU B C   1 
ATOM   8300  O O   . LEU B 1 512 ? 109.734 149.584 145.978 1.00 19.91  ? 512 LEU B O   1 
ATOM   8301  C CB  . LEU B 1 512 ? 109.196 149.749 149.047 1.00 15.26  ? 512 LEU B CB  1 
ATOM   8302  C CG  . LEU B 1 512 ? 108.149 150.517 149.860 1.00 21.07  ? 512 LEU B CG  1 
ATOM   8303  C CD1 . LEU B 1 512 ? 108.672 150.831 151.246 1.00 32.24  ? 512 LEU B CD1 1 
ATOM   8304  C CD2 . LEU B 1 512 ? 107.796 151.844 149.198 1.00 15.70  ? 512 LEU B CD2 1 
ATOM   8305  N N   . LEU B 1 513 ? 110.164 147.504 146.657 1.00 13.74  ? 513 LEU B N   1 
ATOM   8306  C CA  . LEU B 1 513 ? 111.038 147.187 145.534 1.00 14.71  ? 513 LEU B CA  1 
ATOM   8307  C C   . LEU B 1 513 ? 110.308 147.111 144.189 1.00 14.48  ? 513 LEU B C   1 
ATOM   8308  O O   . LEU B 1 513 ? 110.966 147.233 143.161 1.00 28.09  ? 513 LEU B O   1 
ATOM   8309  C CB  . LEU B 1 513 ? 111.824 145.904 145.815 1.00 25.49  ? 513 LEU B CB  1 
ATOM   8310  C CG  . LEU B 1 513 ? 112.767 146.021 147.023 1.00 21.25  ? 513 LEU B CG  1 
ATOM   8311  C CD1 . LEU B 1 513 ? 113.280 144.637 147.385 1.00 19.06  ? 513 LEU B CD1 1 
ATOM   8312  C CD2 . LEU B 1 513 ? 113.954 146.935 146.726 1.00 12.81  ? 513 LEU B CD2 1 
ATOM   8313  N N   . TYR B 1 514 ? 108.976 147.012 144.175 1.00 14.47  ? 514 TYR B N   1 
ATOM   8314  C CA  . TYR B 1 514 ? 108.161 147.166 142.975 1.00 5.89   ? 514 TYR B CA  1 
ATOM   8315  C C   . TYR B 1 514 ? 108.447 148.489 142.252 1.00 11.67  ? 514 TYR B C   1 
ATOM   8316  O O   . TYR B 1 514 ? 108.674 148.511 141.047 1.00 30.46  ? 514 TYR B O   1 
ATOM   8317  C CB  . TYR B 1 514 ? 106.685 147.080 143.373 1.00 12.68  ? 514 TYR B CB  1 
ATOM   8318  C CG  . TYR B 1 514 ? 105.728 147.423 142.258 1.00 16.49  ? 514 TYR B CG  1 
ATOM   8319  C CD1 . TYR B 1 514 ? 105.406 146.471 141.278 1.00 12.12  ? 514 TYR B CD1 1 
ATOM   8320  C CD2 . TYR B 1 514 ? 105.222 148.730 142.162 1.00 15.27  ? 514 TYR B CD2 1 
ATOM   8321  C CE1 . TYR B 1 514 ? 104.589 146.838 140.194 1.00 11.45  ? 514 TYR B CE1 1 
ATOM   8322  C CE2 . TYR B 1 514 ? 104.426 149.108 141.074 1.00 6.72   ? 514 TYR B CE2 1 
ATOM   8323  C CZ  . TYR B 1 514 ? 104.116 148.159 140.081 1.00 11.98  ? 514 TYR B CZ  1 
ATOM   8324  O OH  . TYR B 1 514 ? 103.351 148.506 139.020 1.00 30.84  ? 514 TYR B OH  1 
ATOM   8325  N N   . TYR B 1 515 ? 108.493 149.598 142.990 1.00 21.80  ? 515 TYR B N   1 
ATOM   8326  C CA  . TYR B 1 515 ? 108.612 150.943 142.434 1.00 13.81  ? 515 TYR B CA  1 
ATOM   8327  C C   . TYR B 1 515 ? 109.996 151.267 141.874 1.00 9.76   ? 515 TYR B C   1 
ATOM   8328  O O   . TYR B 1 515 ? 110.176 152.290 141.227 1.00 21.92  ? 515 TYR B O   1 
ATOM   8329  C CB  . TYR B 1 515 ? 108.148 151.977 143.459 1.00 12.60  ? 515 TYR B CB  1 
ATOM   8330  C CG  . TYR B 1 515 ? 106.733 151.758 143.939 1.00 17.10  ? 515 TYR B CG  1 
ATOM   8331  C CD1 . TYR B 1 515 ? 105.638 152.241 143.198 1.00 15.80  ? 515 TYR B CD1 1 
ATOM   8332  C CD2 . TYR B 1 515 ? 106.516 151.049 145.132 1.00 7.40   ? 515 TYR B CD2 1 
ATOM   8333  C CE1 . TYR B 1 515 ? 104.325 152.022 143.653 1.00 11.60  ? 515 TYR B CE1 1 
ATOM   8334  C CE2 . TYR B 1 515 ? 105.211 150.833 145.589 1.00 13.61  ? 515 TYR B CE2 1 
ATOM   8335  C CZ  . TYR B 1 515 ? 104.114 151.315 144.852 1.00 15.97  ? 515 TYR B CZ  1 
ATOM   8336  O OH  . TYR B 1 515 ? 102.868 151.074 145.315 1.00 20.50  ? 515 TYR B OH  1 
ATOM   8337  N N   . THR B 1 516 ? 110.967 150.362 142.001 1.00 10.98  ? 516 THR B N   1 
ATOM   8338  C CA  . THR B 1 516 ? 112.268 150.505 141.336 1.00 17.12  ? 516 THR B CA  1 
ATOM   8339  C C   . THR B 1 516 ? 112.152 150.562 139.813 1.00 21.82  ? 516 THR B C   1 
ATOM   8340  O O   . THR B 1 516 ? 113.020 151.161 139.187 1.00 37.61  ? 516 THR B O   1 
ATOM   8341  C CB  . THR B 1 516 ? 113.259 149.406 141.732 1.00 22.25  ? 516 THR B CB  1 
ATOM   8342  O OG1 . THR B 1 516 ? 112.805 148.134 141.359 1.00 31.57  ? 516 THR B OG1 1 
ATOM   8343  C CG2 . THR B 1 516 ? 113.602 149.411 143.212 1.00 11.50  ? 516 THR B CG2 1 
ATOM   8344  N N   . ARG B 1 517 ? 111.076 150.039 139.208 1.00 17.60  ? 517 ARG B N   1 
ATOM   8345  C CA  . ARG B 1 517 ? 110.765 150.144 137.768 1.00 9.33   ? 517 ARG B CA  1 
ATOM   8346  C C   . ARG B 1 517 ? 110.443 151.554 137.261 1.00 18.53  ? 517 ARG B C   1 
ATOM   8347  O O   . ARG B 1 517 ? 110.438 151.761 136.051 1.00 32.44  ? 517 ARG B O   1 
ATOM   8348  C CB  . ARG B 1 517 ? 109.659 149.144 137.407 1.00 17.52  ? 517 ARG B CB  1 
ATOM   8349  C CG  . ARG B 1 517 ? 108.264 149.552 137.907 1.00 19.87  ? 517 ARG B CG  1 
ATOM   8350  C CD  . ARG B 1 517 ? 107.232 148.437 137.802 1.00 5.49   ? 517 ARG B CD  1 
ATOM   8351  N NE  . ARG B 1 517 ? 107.668 147.255 138.560 1.00 19.08  ? 517 ARG B NE  1 
ATOM   8352  C CZ  . ARG B 1 517 ? 107.434 145.998 138.266 1.00 17.22  ? 517 ARG B CZ  1 
ATOM   8353  N NH1 . ARG B 1 517 ? 108.103 145.052 138.838 1.00 12.05  ? 517 ARG B NH1 1 
ATOM   8354  N NH2 . ARG B 1 517 ? 106.540 145.657 137.390 1.00 24.62  ? 517 ARG B NH2 1 
ATOM   8355  N N   . GLY B 1 518 ? 110.206 152.526 138.141 1.00 27.90  ? 518 GLY B N   1 
ATOM   8356  C CA  . GLY B 1 518 ? 109.920 153.910 137.766 1.00 21.23  ? 518 GLY B CA  1 
ATOM   8357  C C   . GLY B 1 518 ? 111.103 154.664 137.158 1.00 21.86  ? 518 GLY B C   1 
ATOM   8358  O O   . GLY B 1 518 ? 110.896 155.611 136.405 1.00 39.14  ? 518 GLY B O   1 
ATOM   8359  N N   . PHE B 1 519 ? 112.332 154.234 137.432 1.00 10.80  ? 519 PHE B N   1 
ATOM   8360  C CA  . PHE B 1 519 ? 113.555 154.825 136.894 1.00 21.77  ? 519 PHE B CA  1 
ATOM   8361  C C   . PHE B 1 519 ? 114.301 153.813 136.042 1.00 28.02  ? 519 PHE B C   1 
ATOM   8362  O O   . PHE B 1 519 ? 114.362 152.640 136.395 1.00 31.45  ? 519 PHE B O   1 
ATOM   8363  C CB  . PHE B 1 519 ? 114.471 155.313 138.021 1.00 25.26  ? 519 PHE B CB  1 
ATOM   8364  C CG  . PHE B 1 519 ? 113.833 156.282 138.988 1.00 24.89  ? 519 PHE B CG  1 
ATOM   8365  C CD1 . PHE B 1 519 ? 113.596 157.609 138.594 1.00 23.56  ? 519 PHE B CD1 1 
ATOM   8366  C CD2 . PHE B 1 519 ? 113.485 155.858 140.279 1.00 25.48  ? 519 PHE B CD2 1 
ATOM   8367  C CE1 . PHE B 1 519 ? 113.014 158.514 139.494 1.00 27.79  ? 519 PHE B CE1 1 
ATOM   8368  C CE2 . PHE B 1 519 ? 112.915 156.766 141.182 1.00 32.69  ? 519 PHE B CE2 1 
ATOM   8369  C CZ  . PHE B 1 519 ? 112.681 158.094 140.790 1.00 29.14  ? 519 PHE B CZ  1 
ATOM   8370  N N   . GLN B 1 520 ? 114.919 154.252 134.953 1.00 40.23  ? 520 GLN B N   1 
ATOM   8371  C CA  . GLN B 1 520 ? 115.676 153.363 134.073 1.00 34.08  ? 520 GLN B CA  1 
ATOM   8372  C C   . GLN B 1 520 ? 116.837 152.681 134.794 1.00 35.19  ? 520 GLN B C   1 
ATOM   8373  O O   . GLN B 1 520 ? 117.038 151.482 134.647 1.00 35.74  ? 520 GLN B O   1 
ATOM   8374  C CB  . GLN B 1 520 ? 116.144 154.172 132.858 1.00 33.61  ? 520 GLN B CB  1 
ATOM   8375  C CG  . GLN B 1 520 ? 116.824 153.287 131.810 1.00 35.52  ? 520 GLN B CG  1 
ATOM   8376  C CD  . GLN B 1 520 ? 117.002 153.961 130.452 1.00 39.99  ? 520 GLN B CD  1 
ATOM   8377  O OE1 . GLN B 1 520 ? 116.252 154.830 130.035 1.00 43.46  ? 520 GLN B OE1 1 
ATOM   8378  N NE2 . GLN B 1 520 ? 118.002 153.577 129.700 1.00 43.24  ? 520 GLN B NE2 1 
ATOM   8379  N N   . HIS B 1 521 ? 117.572 153.426 135.621 1.00 38.54  ? 521 HIS B N   1 
ATOM   8380  C CA  . HIS B 1 521 ? 118.779 152.946 136.292 1.00 36.47  ? 521 HIS B CA  1 
ATOM   8381  C C   . HIS B 1 521 ? 118.491 151.807 137.276 1.00 35.33  ? 521 HIS B C   1 
ATOM   8382  O O   . HIS B 1 521 ? 119.094 150.733 137.106 1.00 37.80  ? 521 HIS B O   1 
ATOM   8383  C CB  . HIS B 1 521 ? 119.505 154.095 137.007 1.00 36.51  ? 521 HIS B CB  1 
ATOM   8384  C CG  . HIS B 1 521 ? 120.893 153.735 137.418 1.00 42.93  ? 521 HIS B CG  1 
ATOM   8385  N ND1 . HIS B 1 521 ? 121.406 154.055 138.661 1.00 45.28  ? 521 HIS B ND1 1 
ATOM   8386  C CD2 . HIS B 1 521 ? 121.873 153.074 136.764 1.00 37.78  ? 521 HIS B CD2 1 
ATOM   8387  C CE1 . HIS B 1 521 ? 122.645 153.614 138.750 1.00 44.11  ? 521 HIS B CE1 1 
ATOM   8388  N NE2 . HIS B 1 521 ? 122.955 153.007 137.599 1.00 44.67  ? 521 HIS B NE2 1 
ATOM   8389  N N   . THR B 1 522 ? 117.568 151.997 138.222 1.00 34.79  ? 522 THR B N   1 
ATOM   8390  C CA  . THR B 1 522 ? 117.189 150.918 139.173 1.00 32.05  ? 522 THR B CA  1 
ATOM   8391  C C   . THR B 1 522 ? 116.323 149.880 138.451 1.00 32.05  ? 522 THR B C   1 
ATOM   8392  O O   . THR B 1 522 ? 116.595 148.675 138.616 1.00 25.81  ? 522 THR B O   1 
ATOM   8393  C CB  . THR B 1 522 ? 116.464 151.494 140.396 1.00 33.41  ? 522 THR B CB  1 
ATOM   8394  O OG1 . THR B 1 522 ? 115.282 152.151 139.938 1.00 32.17  ? 522 THR B OG1 1 
ATOM   8395  C CG2 . THR B 1 522 ? 117.318 152.467 141.179 1.00 26.45  ? 522 THR B CG2 1 
ATOM   8396  N N   . GLY B 1 523 ? 115.326 150.336 137.685 1.00 36.86  ? 523 GLY B N   1 
ATOM   8397  C CA  . GLY B 1 523 ? 114.431 149.414 136.959 1.00 24.07  ? 523 GLY B CA  1 
ATOM   8398  C C   . GLY B 1 523 ? 115.204 148.323 136.241 1.00 31.16  ? 523 GLY B C   1 
ATOM   8399  O O   . GLY B 1 523 ? 115.051 147.145 136.621 1.00 49.85  ? 523 GLY B O   1 
ATOM   8400  N N   . ILE B 1 524 ? 116.007 148.697 135.241 1.00 29.92  ? 524 ILE B N   1 
ATOM   8401  C CA  . ILE B 1 524 ? 116.783 147.713 134.478 1.00 31.74  ? 524 ILE B CA  1 
ATOM   8402  C C   . ILE B 1 524 ? 117.621 146.830 135.415 1.00 41.79  ? 524 ILE B C   1 
ATOM   8403  O O   . ILE B 1 524 ? 117.723 145.626 135.179 1.00 42.74  ? 524 ILE B O   1 
ATOM   8404  C CB  . ILE B 1 524 ? 117.626 148.437 133.408 1.00 41.04  ? 524 ILE B CB  1 
ATOM   8405  C CG1 . ILE B 1 524 ? 116.675 149.040 132.353 1.00 34.90  ? 524 ILE B CG1 1 
ATOM   8406  C CG2 . ILE B 1 524 ? 118.637 147.502 132.734 1.00 35.45  ? 524 ILE B CG2 1 
ATOM   8407  C CD1 . ILE B 1 524 ? 117.373 149.817 131.244 1.00 31.89  ? 524 ILE B CD1 1 
ATOM   8408  N N   . TYR B 1 525 ? 118.173 147.360 136.511 1.00 37.19  ? 525 TYR B N   1 
ATOM   8409  C CA  . TYR B 1 525 ? 118.924 146.528 137.455 1.00 33.71  ? 525 TYR B CA  1 
ATOM   8410  C C   . TYR B 1 525 ? 118.049 145.505 138.177 1.00 37.89  ? 525 TYR B C   1 
ATOM   8411  O O   . TYR B 1 525 ? 118.427 144.342 138.296 1.00 44.93  ? 525 TYR B O   1 
ATOM   8412  C CB  . TYR B 1 525 ? 119.682 147.386 138.458 1.00 40.27  ? 525 TYR B CB  1 
ATOM   8413  C CG  . TYR B 1 525 ? 120.728 146.592 139.208 1.00 34.78  ? 525 TYR B CG  1 
ATOM   8414  C CD1 . TYR B 1 525 ? 121.856 146.127 138.511 1.00 31.38  ? 525 TYR B CD1 1 
ATOM   8415  C CD2 . TYR B 1 525 ? 120.544 146.251 140.561 1.00 32.65  ? 525 TYR B CD2 1 
ATOM   8416  C CE1 . TYR B 1 525 ? 122.816 145.338 139.161 1.00 43.21  ? 525 TYR B CE1 1 
ATOM   8417  C CE2 . TYR B 1 525 ? 121.504 145.456 141.213 1.00 41.04  ? 525 TYR B CE2 1 
ATOM   8418  C CZ  . TYR B 1 525 ? 122.644 144.999 140.518 1.00 43.96  ? 525 TYR B CZ  1 
ATOM   8419  O OH  . TYR B 1 525 ? 123.554 144.209 141.141 1.00 32.72  ? 525 TYR B OH  1 
ATOM   8420  N N   . SER B 1 526 ? 116.841 145.885 138.577 1.00 26.86  ? 526 SER B N   1 
ATOM   8421  C CA  . SER B 1 526 ? 115.848 144.948 139.096 1.00 34.60  ? 526 SER B CA  1 
ATOM   8422  C C   . SER B 1 526 ? 115.558 143.784 138.134 1.00 39.72  ? 526 SER B C   1 
ATOM   8423  O O   . SER B 1 526 ? 115.353 142.664 138.589 1.00 48.34  ? 526 SER B O   1 
ATOM   8424  C CB  . SER B 1 526 ? 114.585 145.728 139.441 1.00 40.06  ? 526 SER B CB  1 
ATOM   8425  O OG  . SER B 1 526 ? 114.787 146.404 140.661 1.00 46.67  ? 526 SER B OG  1 
ATOM   8426  N N   . VAL B 1 527 ? 115.666 143.995 136.820 1.00 39.54  ? 527 VAL B N   1 
ATOM   8427  C CA  . VAL B 1 527 ? 115.586 142.941 135.799 1.00 40.11  ? 527 VAL B CA  1 
ATOM   8428  C C   . VAL B 1 527 ? 116.876 142.116 135.667 1.00 40.47  ? 527 VAL B C   1 
ATOM   8429  O O   . VAL B 1 527 ? 116.813 140.893 135.607 1.00 42.00  ? 527 VAL B O   1 
ATOM   8430  C CB  . VAL B 1 527 ? 115.193 143.552 134.445 1.00 40.79  ? 527 VAL B CB  1 
ATOM   8431  C CG1 . VAL B 1 527 ? 115.221 142.513 133.336 1.00 42.41  ? 527 VAL B CG1 1 
ATOM   8432  C CG2 . VAL B 1 527 ? 113.783 144.135 134.483 1.00 35.77  ? 527 VAL B CG2 1 
ATOM   8433  N N   . MET B 1 528 ? 118.055 142.744 135.667 1.00 47.86  ? 528 MET B N   1 
ATOM   8434  C CA  . MET B 1 528 ? 119.352 142.042 135.678 1.00 47.15  ? 528 MET B CA  1 
ATOM   8435  C C   . MET B 1 528 ? 119.492 141.099 136.888 1.00 48.01  ? 528 MET B C   1 
ATOM   8436  O O   . MET B 1 528 ? 119.997 139.988 136.770 1.00 49.95  ? 528 MET B O   1 
ATOM   8437  C CB  . MET B 1 528 ? 120.493 143.069 135.703 1.00 47.41  ? 528 MET B CB  1 
ATOM   8438  C CG  . MET B 1 528 ? 120.587 143.901 134.423 1.00 49.07  ? 528 MET B CG  1 
ATOM   8439  S SD  . MET B 1 528 ? 121.646 145.361 134.613 1.00 66.06  ? 528 MET B SD  1 
ATOM   8440  C CE  . MET B 1 528 ? 122.048 145.656 132.873 1.00 50.00  ? 528 MET B CE  1 
ATOM   8441  N N   . ILE B 1 529 ? 118.977 141.513 138.043 1.00 51.56  ? 529 ILE B N   1 
ATOM   8442  C CA  . ILE B 1 529 ? 118.990 140.722 139.319 1.00 51.31  ? 529 ILE B CA  1 
ATOM   8443  C C   . ILE B 1 529 ? 117.986 139.554 139.316 1.00 51.87  ? 529 ILE B C   1 
ATOM   8444  O O   . ILE B 1 529 ? 117.968 138.806 140.284 1.00 60.31  ? 529 ILE B O   1 
ATOM   8445  C CB  . ILE B 1 529 ? 118.754 141.653 140.525 1.00 52.74  ? 529 ILE B CB  1 
ATOM   8446  C CG1 . ILE B 1 529 ? 119.945 142.586 140.752 1.00 54.40  ? 529 ILE B CG1 1 
ATOM   8447  C CG2 . ILE B 1 529 ? 118.426 140.847 141.773 1.00 53.01  ? 529 ILE B CG2 1 
ATOM   8448  C CD1 . ILE B 1 529 ? 121.253 141.861 140.966 1.00 46.50  ? 529 ILE B CD1 1 
ATOM   8449  N N   . GLN B 1 530 ? 117.226 139.279 138.253 1.00 47.24  ? 530 GLN B N   1 
ATOM   8450  C CA  . GLN B 1 530 ? 116.416 138.051 138.146 1.00 41.59  ? 530 GLN B CA  1 
ATOM   8451  C C   . GLN B 1 530 ? 117.193 136.815 137.641 1.00 45.96  ? 530 GLN B C   1 
ATOM   8452  O O   . GLN B 1 530 ? 116.615 135.733 137.620 1.00 48.08  ? 530 GLN B O   1 
ATOM   8453  C CB  . GLN B 1 530 ? 115.200 138.283 137.236 1.00 51.71  ? 530 GLN B CB  1 
ATOM   8454  C CG  . GLN B 1 530 ? 114.337 139.500 137.580 1.00 53.26  ? 530 GLN B CG  1 
ATOM   8455  C CD  . GLN B 1 530 ? 113.753 139.463 138.981 1.00 50.21  ? 530 GLN B CD  1 
ATOM   8456  O OE1 . GLN B 1 530 ? 113.051 138.546 139.373 1.00 57.01  ? 530 GLN B OE1 1 
ATOM   8457  N NE2 . GLN B 1 530 ? 113.965 140.494 139.759 1.00 48.20  ? 530 GLN B NE2 1 
ATOM   8458  N N   . LYS B 1 531 ? 118.457 136.937 137.203 1.00 47.06  ? 531 LYS B N   1 
ATOM   8459  C CA  . LYS B 1 531 ? 119.260 135.892 136.519 1.00 46.17  ? 531 LYS B CA  1 
ATOM   8460  C C   . LYS B 1 531 ? 119.051 134.470 137.048 1.00 49.37  ? 531 LYS B C   1 
ATOM   8461  O O   . LYS B 1 531 ? 118.731 133.560 136.289 1.00 51.03  ? 531 LYS B O   1 
ATOM   8462  C CB  . LYS B 1 531 ? 120.766 136.246 136.633 1.00 46.33  ? 531 LYS B CB  1 
ATOM   8463  C CG  . LYS B 1 531 ? 121.312 137.132 135.507 1.00 46.96  ? 531 LYS B CG  1 
ATOM   8464  C CD  . LYS B 1 531 ? 121.582 136.342 134.222 1.00 48.94  ? 531 LYS B CD  1 
ATOM   8465  C CE  . LYS B 1 531 ? 122.255 137.236 133.174 1.00 52.22  ? 531 LYS B CE  1 
ATOM   8466  N NZ  . LYS B 1 531 ? 122.564 136.498 131.918 1.00 52.14  ? 531 LYS B NZ  1 
ATOM   8467  N N   . VAL B 1 532 ? 119.276 134.274 138.342 1.00 54.32  ? 532 VAL B N   1 
ATOM   8468  C CA  . VAL B 1 532 ? 119.170 133.004 139.066 1.00 49.39  ? 532 VAL B CA  1 
ATOM   8469  C C   . VAL B 1 532 ? 117.733 132.844 139.554 1.00 54.18  ? 532 VAL B C   1 
ATOM   8470  O O   . VAL B 1 532 ? 117.341 133.323 140.620 1.00 57.59  ? 532 VAL B O   1 
ATOM   8471  C CB  . VAL B 1 532 ? 120.200 132.945 140.209 1.00 50.48  ? 532 VAL B CB  1 
ATOM   8472  C CG1 . VAL B 1 532 ? 120.107 131.626 140.971 1.00 51.39  ? 532 VAL B CG1 1 
ATOM   8473  C CG2 . VAL B 1 532 ? 121.624 133.094 139.656 1.00 49.75  ? 532 VAL B CG2 1 
ATOM   8474  N N   . ILE B 1 533 ? 116.920 132.194 138.724 1.00 59.56  ? 533 ILE B N   1 
ATOM   8475  C CA  . ILE B 1 533 ? 115.518 131.883 139.013 1.00 58.40  ? 533 ILE B CA  1 
ATOM   8476  C C   . ILE B 1 533 ? 115.460 130.874 140.175 1.00 51.11  ? 533 ILE B C   1 
ATOM   8477  O O   . ILE B 1 533 ? 116.398 130.107 140.399 1.00 49.52  ? 533 ILE B O   1 
ATOM   8478  C CB  . ILE B 1 533 ? 114.825 131.355 137.721 1.00 53.51  ? 533 ILE B CB  1 
ATOM   8479  C CG1 . ILE B 1 533 ? 115.055 132.254 136.482 1.00 50.59  ? 533 ILE B CG1 1 
ATOM   8480  C CG2 . ILE B 1 533 ? 113.306 131.156 137.875 1.00 52.75  ? 533 ILE B CG2 1 
ATOM   8481  C CD1 . ILE B 1 533 ? 114.403 133.636 136.555 1.00 48.41  ? 533 ILE B CD1 1 
ATOM   8482  N N   . LEU B 1 534 ? 114.325 130.769 140.864 1.00 46.49  ? 534 LEU B N   1 
ATOM   8483  C CA  . LEU B 1 534 ? 114.059 129.629 141.750 1.00 47.81  ? 534 LEU B CA  1 
ATOM   8484  C C   . LEU B 1 534 ? 114.115 128.269 141.032 1.00 49.02  ? 534 LEU B C   1 
ATOM   8485  O O   . LEU B 1 534 ? 114.184 127.253 141.702 1.00 55.50  ? 534 LEU B O   1 
ATOM   8486  C CB  . LEU B 1 534 ? 112.702 129.803 142.455 1.00 52.10  ? 534 LEU B CB  1 
ATOM   8487  C CG  . LEU B 1 534 ? 112.596 131.032 143.371 1.00 54.72  ? 534 LEU B CG  1 
ATOM   8488  C CD1 . LEU B 1 534 ? 111.182 131.100 143.941 1.00 53.65  ? 534 LEU B CD1 1 
ATOM   8489  C CD2 . LEU B 1 534 ? 113.592 130.976 144.527 1.00 52.05  ? 534 LEU B CD2 1 
ATOM   8490  N N   . ARG B 1 535 ? 114.145 128.262 139.694 1.00 47.02  ? 535 ARG B N   1 
ATOM   8491  C CA  . ARG B 1 535 ? 114.188 127.003 138.887 1.00 47.10  ? 535 ARG B CA  1 
ATOM   8492  C C   . ARG B 1 535 ? 115.326 126.094 139.365 1.00 47.08  ? 535 ARG B C   1 
ATOM   8493  O O   . ARG B 1 535 ? 115.063 124.895 139.584 1.00 48.92  ? 535 ARG B O   1 
ATOM   8494  C CB  . ARG B 1 535 ? 114.331 127.405 137.411 1.00 49.32  ? 535 ARG B CB  1 
ATOM   8495  C CG  . ARG B 1 535 ? 114.136 126.234 136.437 1.00 47.93  ? 535 ARG B CG  1 
ATOM   8496  C CD  . ARG B 1 535 ? 114.800 126.522 135.092 1.00 47.60  ? 535 ARG B CD  1 
ATOM   8497  N NE  . ARG B 1 535 ? 116.247 126.595 135.243 1.00 50.84  ? 535 ARG B NE  1 
ATOM   8498  C CZ  . ARG B 1 535 ? 117.106 126.773 134.246 1.00 51.33  ? 535 ARG B CZ  1 
ATOM   8499  N NH1 . ARG B 1 535 ? 118.403 126.823 134.494 1.00 45.90  ? 535 ARG B NH1 1 
ATOM   8500  N NH2 . ARG B 1 535 ? 116.665 126.898 133.007 1.00 49.27  ? 535 ARG B NH2 1 
ATOM   8501  N N   . ASP B 1 536 ? 116.535 126.640 139.517 1.00 41.47  ? 536 ASP B N   1 
ATOM   8502  C CA  . ASP B 1 536 ? 117.694 125.840 139.926 1.00 37.39  ? 536 ASP B CA  1 
ATOM   8503  C C   . ASP B 1 536 ? 117.854 125.782 141.440 1.00 40.90  ? 536 ASP B C   1 
ATOM   8504  O O   . ASP B 1 536 ? 118.095 124.712 141.982 1.00 46.81  ? 536 ASP B O   1 
ATOM   8505  C CB  . ASP B 1 536 ? 118.967 126.297 139.212 1.00 40.80  ? 536 ASP B CB  1 
ATOM   8506  C CG  . ASP B 1 536 ? 118.936 125.996 137.707 1.00 46.75  ? 536 ASP B CG  1 
ATOM   8507  O OD1 . ASP B 1 536 ? 117.927 125.446 137.214 1.00 46.54  ? 536 ASP B OD1 1 
ATOM   8508  O OD2 . ASP B 1 536 ? 119.900 126.314 136.989 1.00 47.40  ? 536 ASP B OD2 1 
ATOM   8509  N N   . LEU B 1 537 ? 117.643 126.880 142.162 1.00 39.50  ? 537 LEU B N   1 
ATOM   8510  C CA  . LEU B 1 537 ? 117.772 126.873 143.617 1.00 33.77  ? 537 LEU B CA  1 
ATOM   8511  C C   . LEU B 1 537 ? 116.714 126.018 144.322 1.00 40.21  ? 537 LEU B C   1 
ATOM   8512  O O   . LEU B 1 537 ? 117.049 125.388 145.314 1.00 49.38  ? 537 LEU B O   1 
ATOM   8513  C CB  . LEU B 1 537 ? 117.838 128.311 144.153 1.00 36.89  ? 537 LEU B CB  1 
ATOM   8514  C CG  . LEU B 1 537 ? 119.289 128.716 144.430 1.00 41.91  ? 537 LEU B CG  1 
ATOM   8515  C CD1 . LEU B 1 537 ? 120.176 128.671 143.192 1.00 41.74  ? 537 LEU B CD1 1 
ATOM   8516  C CD2 . LEU B 1 537 ? 119.325 130.121 145.000 1.00 44.21  ? 537 LEU B CD2 1 
ATOM   8517  N N   . LEU B 1 538 ? 115.487 125.893 143.809 1.00 40.83  ? 538 LEU B N   1 
ATOM   8518  C CA  . LEU B 1 538 ? 114.490 124.962 144.347 1.00 43.94  ? 538 LEU B CA  1 
ATOM   8519  C C   . LEU B 1 538 ? 114.847 123.489 144.076 1.00 40.94  ? 538 LEU B C   1 
ATOM   8520  O O   . LEU B 1 538 ? 114.486 122.608 144.851 1.00 45.46  ? 538 LEU B O   1 
ATOM   8521  C CB  . LEU B 1 538 ? 113.107 125.337 143.775 1.00 44.76  ? 538 LEU B CB  1 
ATOM   8522  C CG  . LEU B 1 538 ? 111.906 124.555 144.319 1.00 46.80  ? 538 LEU B CG  1 
ATOM   8523  C CD1 . LEU B 1 538 ? 111.746 124.691 145.823 1.00 43.12  ? 538 LEU B CD1 1 
ATOM   8524  C CD2 . LEU B 1 538 ? 110.636 125.074 143.664 1.00 43.33  ? 538 LEU B CD2 1 
ATOM   8525  N N   . ARG B 1 539 ? 115.625 123.248 143.007 1.00 32.43  ? 539 ARG B N   1 
ATOM   8526  C CA  . ARG B 1 539 ? 116.090 121.863 142.679 1.00 30.20  ? 539 ARG B CA  1 
ATOM   8527  C C   . ARG B 1 539 ? 117.292 121.546 143.579 1.00 34.69  ? 539 ARG B C   1 
ATOM   8528  O O   . ARG B 1 539 ? 117.280 120.469 144.207 1.00 46.82  ? 539 ARG B O   1 
ATOM   8529  C CB  . ARG B 1 539 ? 116.253 121.729 141.162 1.00 41.51  ? 539 ARG B CB  1 
ATOM   8530  C CG  . ARG B 1 539 ? 114.912 121.807 140.426 1.00 42.33  ? 539 ARG B CG  1 
ATOM   8531  C CD  . ARG B 1 539 ? 115.056 121.414 138.956 1.00 38.32  ? 539 ARG B CD  1 
ATOM   8532  N NE  . ARG B 1 539 ? 115.923 122.333 138.233 1.00 40.36  ? 539 ARG B NE  1 
ATOM   8533  C CZ  . ARG B 1 539 ? 116.183 122.259 136.932 1.00 41.43  ? 539 ARG B CZ  1 
ATOM   8534  N NH1 . ARG B 1 539 ? 116.986 123.143 136.366 1.00 39.17  ? 539 ARG B NH1 1 
ATOM   8535  N NH2 . ARG B 1 539 ? 115.637 121.303 136.202 1.00 36.79  ? 539 ARG B NH2 1 
ATOM   8536  N N   . PHE B 1 540 ? 118.277 122.441 143.652 1.00 36.16  ? 540 PHE B N   1 
ATOM   8537  C CA  . PHE B 1 540 ? 119.402 122.311 144.584 1.00 31.41  ? 540 PHE B CA  1 
ATOM   8538  C C   . PHE B 1 540 ? 118.909 122.122 146.020 1.00 25.90  ? 540 PHE B C   1 
ATOM   8539  O O   . PHE B 1 540 ? 119.440 121.281 146.741 1.00 28.93  ? 540 PHE B O   1 
ATOM   8540  C CB  . PHE B 1 540 ? 120.315 123.541 144.454 1.00 31.28  ? 540 PHE B CB  1 
ATOM   8541  C CG  . PHE B 1 540 ? 121.027 123.948 145.729 1.00 38.71  ? 540 PHE B CG  1 
ATOM   8542  C CD1 . PHE B 1 540 ? 122.213 123.303 146.133 1.00 36.41  ? 540 PHE B CD1 1 
ATOM   8543  C CD2 . PHE B 1 540 ? 120.467 124.948 146.547 1.00 35.25  ? 540 PHE B CD2 1 
ATOM   8544  C CE1 . PHE B 1 540 ? 122.818 123.647 147.350 1.00 27.55  ? 540 PHE B CE1 1 
ATOM   8545  C CE2 . PHE B 1 540 ? 121.055 125.269 147.776 1.00 32.86  ? 540 PHE B CE2 1 
ATOM   8546  C CZ  . PHE B 1 540 ? 122.231 124.617 148.176 1.00 33.03  ? 540 PHE B CZ  1 
ATOM   8547  N N   . LEU B 1 541 ? 117.862 122.844 146.421 1.00 19.20  ? 541 LEU B N   1 
ATOM   8548  C CA  . LEU B 1 541 ? 117.277 122.748 147.746 1.00 28.68  ? 541 LEU B CA  1 
ATOM   8549  C C   . LEU B 1 541 ? 116.786 121.337 148.068 1.00 29.19  ? 541 LEU B C   1 
ATOM   8550  O O   . LEU B 1 541 ? 116.990 120.877 149.179 1.00 37.90  ? 541 LEU B O   1 
ATOM   8551  C CB  . LEU B 1 541 ? 116.156 123.793 147.868 1.00 33.04  ? 541 LEU B CB  1 
ATOM   8552  C CG  . LEU B 1 541 ? 115.487 123.860 149.246 1.00 32.91  ? 541 LEU B CG  1 
ATOM   8553  C CD1 . LEU B 1 541 ? 116.441 124.400 150.310 1.00 30.39  ? 541 LEU B CD1 1 
ATOM   8554  C CD2 . LEU B 1 541 ? 114.280 124.782 149.168 1.00 32.93  ? 541 LEU B CD2 1 
ATOM   8555  N N   . LEU B 1 542 ? 116.216 120.604 147.108 1.00 26.34  ? 542 LEU B N   1 
ATOM   8556  C CA  . LEU B 1 542 ? 115.842 119.206 147.298 1.00 22.34  ? 542 LEU B CA  1 
ATOM   8557  C C   . LEU B 1 542 ? 117.041 118.333 147.693 1.00 20.49  ? 542 LEU B C   1 
ATOM   8558  O O   . LEU B 1 542 ? 116.979 117.605 148.676 1.00 32.24  ? 542 LEU B O   1 
ATOM   8559  C CB  . LEU B 1 542 ? 115.150 118.708 146.015 1.00 28.65  ? 542 LEU B CB  1 
ATOM   8560  C CG  . LEU B 1 542 ? 114.729 117.229 146.033 1.00 29.21  ? 542 LEU B CG  1 
ATOM   8561  C CD1 . LEU B 1 542 ? 113.667 116.941 147.085 1.00 31.51  ? 542 LEU B CD1 1 
ATOM   8562  C CD2 . LEU B 1 542 ? 114.165 116.851 144.673 1.00 23.63  ? 542 LEU B CD2 1 
ATOM   8563  N N   . VAL B 1 543 ? 118.158 118.438 146.975 1.00 21.26  ? 543 VAL B N   1 
ATOM   8564  C CA  . VAL B 1 543 ? 119.383 117.692 147.294 1.00 19.67  ? 543 VAL B CA  1 
ATOM   8565  C C   . VAL B 1 543 ? 119.970 118.133 148.631 1.00 21.93  ? 543 VAL B C   1 
ATOM   8566  O O   . VAL B 1 543 ? 120.293 117.298 149.473 1.00 30.93  ? 543 VAL B O   1 
ATOM   8567  C CB  . VAL B 1 543 ? 120.428 117.826 146.170 1.00 22.11  ? 543 VAL B CB  1 
ATOM   8568  C CG1 . VAL B 1 543 ? 121.674 116.994 146.459 1.00 20.68  ? 543 VAL B CG1 1 
ATOM   8569  C CG2 . VAL B 1 543 ? 119.843 117.356 144.840 1.00 24.61  ? 543 VAL B CG2 1 
ATOM   8570  N N   . TYR B 1 544 ? 120.056 119.442 148.857 1.00 29.66  ? 544 TYR B N   1 
ATOM   8571  C CA  . TYR B 1 544 ? 120.568 120.007 150.091 1.00 11.40  ? 544 TYR B CA  1 
ATOM   8572  C C   . TYR B 1 544 ? 119.745 119.613 151.325 1.00 14.48  ? 544 TYR B C   1 
ATOM   8573  O O   . TYR B 1 544 ? 120.324 119.281 152.350 1.00 29.68  ? 544 TYR B O   1 
ATOM   8574  C CB  . TYR B 1 544 ? 120.710 121.526 149.971 1.00 19.05  ? 544 TYR B CB  1 
ATOM   8575  C CG  . TYR B 1 544 ? 121.184 122.151 151.255 1.00 30.63  ? 544 TYR B CG  1 
ATOM   8576  C CD1 . TYR B 1 544 ? 122.517 122.095 151.618 1.00 25.03  ? 544 TYR B CD1 1 
ATOM   8577  C CD2 . TYR B 1 544 ? 120.293 122.735 152.136 1.00 23.56  ? 544 TYR B CD2 1 
ATOM   8578  C CE1 . TYR B 1 544 ? 122.959 122.630 152.813 1.00 22.27  ? 544 TYR B CE1 1 
ATOM   8579  C CE2 . TYR B 1 544 ? 120.718 123.271 153.338 1.00 16.54  ? 544 TYR B CE2 1 
ATOM   8580  C CZ  . TYR B 1 544 ? 122.056 123.224 153.673 1.00 28.73  ? 544 TYR B CZ  1 
ATOM   8581  O OH  . TYR B 1 544 ? 122.486 123.758 154.849 1.00 39.08  ? 544 TYR B OH  1 
ATOM   8582  N N   . LEU B 1 545 ? 118.414 119.608 151.259 1.00 10.84  ? 545 LEU B N   1 
ATOM   8583  C CA  . LEU B 1 545 ? 117.575 119.222 152.394 1.00 16.93  ? 545 LEU B CA  1 
ATOM   8584  C C   . LEU B 1 545 ? 117.646 117.727 152.699 1.00 17.13  ? 545 LEU B C   1 
ATOM   8585  O O   . LEU B 1 545 ? 117.571 117.343 153.861 1.00 27.95  ? 545 LEU B O   1 
ATOM   8586  C CB  . LEU B 1 545 ? 116.128 119.672 152.164 1.00 24.28  ? 545 LEU B CB  1 
ATOM   8587  C CG  . LEU B 1 545 ? 115.899 121.192 152.237 1.00 26.90  ? 545 LEU B CG  1 
ATOM   8588  C CD1 . LEU B 1 545 ? 114.418 121.465 152.003 1.00 26.33  ? 545 LEU B CD1 1 
ATOM   8589  C CD2 . LEU B 1 545 ? 116.294 121.805 153.576 1.00 18.91  ? 545 LEU B CD2 1 
ATOM   8590  N N   . VAL B 1 546 ? 117.854 116.870 151.700 1.00 26.76  ? 546 VAL B N   1 
ATOM   8591  C CA  . VAL B 1 546 ? 118.143 115.449 151.932 1.00 17.52  ? 546 VAL B CA  1 
ATOM   8592  C C   . VAL B 1 546 ? 119.485 115.267 152.644 1.00 24.60  ? 546 VAL B C   1 
ATOM   8593  O O   . VAL B 1 546 ? 119.549 114.504 153.603 1.00 32.21  ? 546 VAL B O   1 
ATOM   8594  C CB  . VAL B 1 546 ? 118.060 114.648 150.622 1.00 22.01  ? 546 VAL B CB  1 
ATOM   8595  C CG1 . VAL B 1 546 ? 118.557 113.213 150.785 1.00 19.88  ? 546 VAL B CG1 1 
ATOM   8596  C CG2 . VAL B 1 546 ? 116.609 114.572 150.147 1.00 21.98  ? 546 VAL B CG2 1 
ATOM   8597  N N   . PHE B 1 547 ? 120.534 115.994 152.246 1.00 26.33  ? 547 PHE B N   1 
ATOM   8598  C CA  . PHE B 1 547 ? 121.822 115.945 152.988 1.00 13.54  ? 547 PHE B CA  1 
ATOM   8599  C C   . PHE B 1 547 ? 121.611 116.496 154.403 1.00 18.12  ? 547 PHE B C   1 
ATOM   8600  O O   . PHE B 1 547 ? 121.994 115.822 155.350 1.00 34.33  ? 547 PHE B O   1 
ATOM   8601  C CB  . PHE B 1 547 ? 122.905 116.726 152.238 1.00 18.05  ? 547 PHE B CB  1 
ATOM   8602  C CG  . PHE B 1 547 ? 123.539 115.986 151.086 1.00 23.53  ? 547 PHE B CG  1 
ATOM   8603  C CD1 . PHE B 1 547 ? 122.864 115.829 149.887 1.00 30.28  ? 547 PHE B CD1 1 
ATOM   8604  C CD2 . PHE B 1 547 ? 124.812 115.452 151.201 1.00 34.62  ? 547 PHE B CD2 1 
ATOM   8605  C CE1 . PHE B 1 547 ? 123.447 115.148 148.828 1.00 29.57  ? 547 PHE B CE1 1 
ATOM   8606  C CE2 . PHE B 1 547 ? 125.394 114.774 150.142 1.00 30.59  ? 547 PHE B CE2 1 
ATOM   8607  C CZ  . PHE B 1 547 ? 124.711 114.623 148.958 1.00 24.93  ? 547 PHE B CZ  1 
ATOM   8608  N N   . LEU B 1 548 ? 120.980 117.657 154.570 1.00 25.17  ? 548 LEU B N   1 
ATOM   8609  C CA  . LEU B 1 548 ? 120.737 118.288 155.858 1.00 16.53  ? 548 LEU B CA  1 
ATOM   8610  C C   . LEU B 1 548 ? 120.002 117.361 156.820 1.00 15.31  ? 548 LEU B C   1 
ATOM   8611  O O   . LEU B 1 548 ? 120.501 117.082 157.904 1.00 33.86  ? 548 LEU B O   1 
ATOM   8612  C CB  . LEU B 1 548 ? 119.958 119.591 155.626 1.00 26.07  ? 548 LEU B CB  1 
ATOM   8613  C CG  . LEU B 1 548 ? 119.697 120.395 156.907 1.00 29.16  ? 548 LEU B CG  1 
ATOM   8614  C CD1 . LEU B 1 548 ? 120.997 120.981 157.436 1.00 22.31  ? 548 LEU B CD1 1 
ATOM   8615  C CD2 . LEU B 1 548 ? 118.720 121.525 156.622 1.00 26.04  ? 548 LEU B CD2 1 
ATOM   8616  N N   . PHE B 1 549 ? 118.831 116.853 156.447 1.00 20.69  ? 549 PHE B N   1 
ATOM   8617  C CA  . PHE B 1 549 ? 118.037 116.036 157.350 1.00 22.94  ? 549 PHE B CA  1 
ATOM   8618  C C   . PHE B 1 549 ? 118.598 114.626 157.540 1.00 21.46  ? 549 PHE B C   1 
ATOM   8619  O O   . PHE B 1 549 ? 118.545 114.120 158.656 1.00 37.55  ? 549 PHE B O   1 
ATOM   8620  C CB  . PHE B 1 549 ? 116.567 116.053 156.921 1.00 23.52  ? 549 PHE B CB  1 
ATOM   8621  C CG  . PHE B 1 549 ? 115.948 117.444 156.896 1.00 32.21  ? 549 PHE B CG  1 
ATOM   8622  C CD1 . PHE B 1 549 ? 116.151 118.346 157.961 1.00 28.05  ? 549 PHE B CD1 1 
ATOM   8623  C CD2 . PHE B 1 549 ? 115.152 117.841 155.808 1.00 35.09  ? 549 PHE B CD2 1 
ATOM   8624  C CE1 . PHE B 1 549 ? 115.589 119.630 157.925 1.00 26.13  ? 549 PHE B CE1 1 
ATOM   8625  C CE2 . PHE B 1 549 ? 114.584 119.126 155.776 1.00 30.84  ? 549 PHE B CE2 1 
ATOM   8626  C CZ  . PHE B 1 549 ? 114.806 120.022 156.828 1.00 27.61  ? 549 PHE B CZ  1 
ATOM   8627  N N   . GLY B 1 550 ? 119.218 114.021 156.525 1.00 17.43  ? 550 GLY B N   1 
ATOM   8628  C CA  . GLY B 1 550 ? 119.910 112.742 156.657 1.00 14.65  ? 550 GLY B CA  1 
ATOM   8629  C C   . GLY B 1 550 ? 121.057 112.786 157.667 1.00 22.20  ? 550 GLY B C   1 
ATOM   8630  O O   . GLY B 1 550 ? 121.135 111.928 158.543 1.00 32.42  ? 550 GLY B O   1 
ATOM   8631  N N   . PHE B 1 551 ? 121.917 113.808 157.613 1.00 19.87  ? 551 PHE B N   1 
ATOM   8632  C CA  . PHE B 1 551 ? 122.963 113.992 158.615 1.00 11.81  ? 551 PHE B CA  1 
ATOM   8633  C C   . PHE B 1 551 ? 122.427 114.502 159.963 1.00 15.32  ? 551 PHE B C   1 
ATOM   8634  O O   . PHE B 1 551 ? 122.969 114.125 160.995 1.00 26.23  ? 551 PHE B O   1 
ATOM   8635  C CB  . PHE B 1 551 ? 124.079 114.880 158.056 1.00 10.67  ? 551 PHE B CB  1 
ATOM   8636  C CG  . PHE B 1 551 ? 125.061 114.153 157.161 1.00 12.88  ? 551 PHE B CG  1 
ATOM   8637  C CD1 . PHE B 1 551 ? 126.175 113.511 157.728 1.00 12.08  ? 551 PHE B CD1 1 
ATOM   8638  C CD2 . PHE B 1 551 ? 124.907 114.144 155.762 1.00 11.13  ? 551 PHE B CD2 1 
ATOM   8639  C CE1 . PHE B 1 551 ? 127.126 112.886 156.912 1.00 12.39  ? 551 PHE B CE1 1 
ATOM   8640  C CE2 . PHE B 1 551 ? 125.858 113.528 154.946 1.00 7.38   ? 551 PHE B CE2 1 
ATOM   8641  C CZ  . PHE B 1 551 ? 126.976 112.900 155.518 1.00 17.30  ? 551 PHE B CZ  1 
ATOM   8642  N N   . ALA B 1 552 ? 121.348 115.286 160.013 1.00 21.79  ? 552 ALA B N   1 
ATOM   8643  C CA  . ALA B 1 552 ? 120.746 115.706 161.273 1.00 18.96  ? 552 ALA B CA  1 
ATOM   8644  C C   . ALA B 1 552 ? 120.179 114.530 162.086 1.00 24.72  ? 552 ALA B C   1 
ATOM   8645  O O   . ALA B 1 552 ? 120.487 114.420 163.269 1.00 32.93  ? 552 ALA B O   1 
ATOM   8646  C CB  . ALA B 1 552 ? 119.672 116.763 161.008 1.00 20.55  ? 552 ALA B CB  1 
ATOM   8647  N N   . VAL B 1 553 ? 119.404 113.615 161.484 1.00 27.90  ? 553 VAL B N   1 
ATOM   8648  C CA  . VAL B 1 553 ? 118.895 112.430 162.203 1.00 23.67  ? 553 VAL B CA  1 
ATOM   8649  C C   . VAL B 1 553 ? 120.033 111.540 162.693 1.00 21.27  ? 553 VAL B C   1 
ATOM   8650  O O   . VAL B 1 553 ? 119.977 111.028 163.807 1.00 25.54  ? 553 VAL B O   1 
ATOM   8651  C CB  . VAL B 1 553 ? 117.857 111.614 161.396 1.00 23.54  ? 553 VAL B CB  1 
ATOM   8652  C CG1 . VAL B 1 553 ? 116.608 112.435 161.088 1.00 23.23  ? 553 VAL B CG1 1 
ATOM   8653  C CG2 . VAL B 1 553 ? 118.356 111.007 160.084 1.00 22.05  ? 553 VAL B CG2 1 
ATOM   8654  N N   . ALA B 1 554 ? 121.098 111.410 161.908 1.00 22.00  ? 554 ALA B N   1 
ATOM   8655  C CA  . ALA B 1 554 ? 122.286 110.646 162.256 1.00 17.02  ? 554 ALA B CA  1 
ATOM   8656  C C   . ALA B 1 554 ? 123.075 111.231 163.435 1.00 22.95  ? 554 ALA B C   1 
ATOM   8657  O O   . ALA B 1 554 ? 123.375 110.504 164.381 1.00 27.73  ? 554 ALA B O   1 
ATOM   8658  C CB  . ALA B 1 554 ? 123.135 110.554 160.999 1.00 17.90  ? 554 ALA B CB  1 
ATOM   8659  N N   . LEU B 1 555 ? 123.362 112.536 163.434 1.00 30.11  ? 555 LEU B N   1 
ATOM   8660  C CA  . LEU B 1 555 ? 124.044 113.207 164.542 1.00 24.47  ? 555 LEU B CA  1 
ATOM   8661  C C   . LEU B 1 555 ? 123.244 113.165 165.838 1.00 25.43  ? 555 LEU B C   1 
ATOM   8662  O O   . LEU B 1 555 ? 123.817 112.875 166.883 1.00 30.90  ? 555 LEU B O   1 
ATOM   8663  C CB  . LEU B 1 555 ? 124.361 114.664 164.174 1.00 26.90  ? 555 LEU B CB  1 
ATOM   8664  C CG  . LEU B 1 555 ? 125.492 114.804 163.149 1.00 28.28  ? 555 LEU B CG  1 
ATOM   8665  C CD1 . LEU B 1 555 ? 125.586 116.259 162.726 1.00 32.03  ? 555 LEU B CD1 1 
ATOM   8666  C CD2 . LEU B 1 555 ? 126.851 114.403 163.711 1.00 27.83  ? 555 LEU B CD2 1 
ATOM   8667  N N   . VAL B 1 556 ? 121.931 113.391 165.795 1.00 22.70  ? 556 VAL B N   1 
ATOM   8668  C CA  . VAL B 1 556 ? 121.083 113.291 166.989 1.00 27.39  ? 556 VAL B CA  1 
ATOM   8669  C C   . VAL B 1 556 ? 121.089 111.878 167.558 1.00 29.23  ? 556 VAL B C   1 
ATOM   8670  O O   . VAL B 1 556 ? 121.295 111.705 168.753 1.00 34.43  ? 556 VAL B O   1 
ATOM   8671  C CB  . VAL B 1 556 ? 119.652 113.766 166.697 1.00 27.41  ? 556 VAL B CB  1 
ATOM   8672  C CG1 . VAL B 1 556 ? 118.695 113.542 167.866 1.00 27.23  ? 556 VAL B CG1 1 
ATOM   8673  C CG2 . VAL B 1 556 ? 119.666 115.260 166.410 1.00 29.29  ? 556 VAL B CG2 1 
ATOM   8674  N N   . SER B 1 557 ? 120.938 110.860 166.710 1.00 35.18  ? 557 SER B N   1 
ATOM   8675  C CA  . SER B 1 557 ? 120.940 109.453 167.127 1.00 27.01  ? 557 SER B CA  1 
ATOM   8676  C C   . SER B 1 557 ? 122.259 109.027 167.774 1.00 30.70  ? 557 SER B C   1 
ATOM   8677  O O   . SER B 1 557 ? 122.260 108.342 168.791 1.00 36.43  ? 557 SER B O   1 
ATOM   8678  C CB  . SER B 1 557 ? 120.655 108.544 165.930 1.00 25.48  ? 557 SER B CB  1 
ATOM   8679  O OG  . SER B 1 557 ? 119.433 108.897 165.317 1.00 35.32  ? 557 SER B OG  1 
ATOM   8680  N N   . LEU B 1 558 ? 123.392 109.447 167.207 1.00 30.28  ? 558 LEU B N   1 
ATOM   8681  C CA  . LEU B 1 558 ? 124.713 109.038 167.663 1.00 28.12  ? 558 LEU B CA  1 
ATOM   8682  C C   . LEU B 1 558 ? 125.214 109.820 168.892 1.00 36.05  ? 558 LEU B C   1 
ATOM   8683  O O   . LEU B 1 558 ? 125.990 109.300 169.684 1.00 40.88  ? 558 LEU B O   1 
ATOM   8684  C CB  . LEU B 1 558 ? 125.663 109.141 166.462 1.00 22.27  ? 558 LEU B CB  1 
ATOM   8685  C CG  . LEU B 1 558 ? 126.978 108.374 166.627 1.00 29.64  ? 558 LEU B CG  1 
ATOM   8686  C CD1 . LEU B 1 558 ? 126.779 106.866 166.784 1.00 31.65  ? 558 LEU B CD1 1 
ATOM   8687  C CD2 . LEU B 1 558 ? 127.826 108.583 165.385 1.00 30.92  ? 558 LEU B CD2 1 
ATOM   8688  N N   . SER B 1 559 ? 124.729 111.044 169.103 1.00 41.73  ? 559 SER B N   1 
ATOM   8689  C CA  . SER B 1 559 ? 125.096 111.902 170.242 1.00 35.44  ? 559 SER B CA  1 
ATOM   8690  C C   . SER B 1 559 ? 124.329 111.605 171.540 1.00 42.84  ? 559 SER B C   1 
ATOM   8691  O O   . SER B 1 559 ? 124.554 112.273 172.548 1.00 50.01  ? 559 SER B O   1 
ATOM   8692  C CB  . SER B 1 559 ? 124.919 113.375 169.875 1.00 38.85  ? 559 SER B CB  1 
ATOM   8693  O OG  . SER B 1 559 ? 125.596 113.651 168.671 1.00 42.50  ? 559 SER B OG  1 
ATOM   8694  N N   . ARG B 1 560 ? 123.428 110.618 171.557 1.00 46.05  ? 560 ARG B N   1 
ATOM   8695  C CA  . ARG B 1 560 ? 122.668 110.210 172.756 1.00 46.31  ? 560 ARG B CA  1 
ATOM   8696  C C   . ARG B 1 560 ? 123.540 109.655 173.883 1.00 50.34  ? 560 ARG B C   1 
ATOM   8697  O O   . ARG B 1 560 ? 123.146 109.706 175.044 1.00 53.44  ? 560 ARG B O   1 
ATOM   8698  C CB  . ARG B 1 560 ? 121.655 109.123 172.375 1.00 46.41  ? 560 ARG B CB  1 
ATOM   8699  C CG  . ARG B 1 560 ? 120.513 109.614 171.491 1.00 44.38  ? 560 ARG B CG  1 
ATOM   8700  C CD  . ARG B 1 560 ? 119.493 110.443 172.272 1.00 47.20  ? 560 ARG B CD  1 
ATOM   8701  N NE  . ARG B 1 560 ? 118.478 111.056 171.396 1.00 52.18  ? 560 ARG B NE  1 
ATOM   8702  C CZ  . ARG B 1 560 ? 117.569 110.442 170.670 1.00 48.53  ? 560 ARG B CZ  1 
ATOM   8703  N NH1 . ARG B 1 560 ? 116.695 111.124 169.995 1.00 46.96  ? 560 ARG B NH1 1 
ATOM   8704  N NH2 . ARG B 1 560 ? 117.491 109.148 170.613 1.00 47.72  ? 560 ARG B NH2 1 
ATOM   8705  N N   . GLU B 1 561 ? 124.699 109.101 173.543 1.00 52.51  ? 561 GLU B N   1 
ATOM   8706  C CA  . GLU B 1 561 ? 125.585 108.410 174.473 1.00 54.27  ? 561 GLU B CA  1 
ATOM   8707  C C   . GLU B 1 561 ? 126.762 109.287 174.913 1.00 58.06  ? 561 GLU B C   1 
ATOM   8708  O O   . GLU B 1 561 ? 127.545 109.761 174.092 1.00 56.00  ? 561 GLU B O   1 
ATOM   8709  C CB  . GLU B 1 561 ? 126.105 107.126 173.803 1.00 55.99  ? 561 GLU B CB  1 
ATOM   8710  C CG  . GLU B 1 561 ? 125.044 106.026 173.642 1.00 57.52  ? 561 GLU B CG  1 
ATOM   8711  C CD  . GLU B 1 561 ? 124.460 105.540 174.978 1.00 60.26  ? 561 GLU B CD  1 
ATOM   8712  O OE1 . GLU B 1 561 ? 125.147 105.642 176.019 1.00 60.36  ? 561 GLU B OE1 1 
ATOM   8713  O OE2 . GLU B 1 561 ? 123.313 105.042 174.979 1.00 60.18  ? 561 GLU B OE2 1 
ATOM   8714  N N   . ALA B 1 562 ? 126.921 109.480 176.225 1.00 61.93  ? 562 ALA B N   1 
ATOM   8715  C CA  . ALA B 1 562 ? 128.051 110.183 176.820 1.00 60.80  ? 562 ALA B CA  1 
ATOM   8716  C C   . ALA B 1 562 ? 129.248 109.253 177.120 1.00 59.90  ? 562 ALA B C   1 
ATOM   8717  O O   . ALA B 1 562 ? 129.079 108.047 177.298 1.00 62.46  ? 562 ALA B O   1 
ATOM   8718  C CB  . ALA B 1 562 ? 127.556 110.899 178.076 1.00 59.37  ? 562 ALA B CB  1 
ATOM   8719  N N   . ARG B 1 563 ? 130.453 109.812 177.220 1.00 59.73  ? 563 ARG B N   1 
ATOM   8720  C CA  . ARG B 1 563 ? 131.676 109.099 177.606 1.00 62.22  ? 563 ARG B CA  1 
ATOM   8721  C C   . ARG B 1 563 ? 132.699 110.004 178.304 1.00 64.54  ? 563 ARG B C   1 
ATOM   8722  O O   . ARG B 1 563 ? 132.780 111.207 178.042 1.00 64.27  ? 563 ARG B O   1 
ATOM   8723  C CB  . ARG B 1 563 ? 132.318 108.464 176.376 1.00 59.90  ? 563 ARG B CB  1 
ATOM   8724  N N   . PRO B 1 589 ? 124.488 120.010 171.890 1.00 54.87  ? 589 PRO B N   1 
ATOM   8725  C CA  . PRO B 1 589 ? 124.842 118.603 172.018 1.00 54.32  ? 589 PRO B CA  1 
ATOM   8726  C C   . PRO B 1 589 ? 124.162 117.687 170.991 1.00 51.55  ? 589 PRO B C   1 
ATOM   8727  O O   . PRO B 1 589 ? 124.127 116.474 171.184 1.00 53.95  ? 589 PRO B O   1 
ATOM   8728  C CB  . PRO B 1 589 ? 124.475 118.231 173.459 1.00 50.66  ? 589 PRO B CB  1 
ATOM   8729  C CG  . PRO B 1 589 ? 124.570 119.553 174.209 1.00 48.34  ? 589 PRO B CG  1 
ATOM   8730  C CD  . PRO B 1 589 ? 124.081 120.553 173.167 1.00 52.58  ? 589 PRO B CD  1 
ATOM   8731  N N   . TYR B 1 590 ? 123.568 118.259 169.938 1.00 40.57  ? 590 TYR B N   1 
ATOM   8732  C CA  . TYR B 1 590 ? 122.661 117.595 168.989 1.00 37.04  ? 590 TYR B CA  1 
ATOM   8733  C C   . TYR B 1 590 ? 121.459 116.955 169.704 1.00 39.51  ? 590 TYR B C   1 
ATOM   8734  O O   . TYR B 1 590 ? 121.213 115.756 169.608 1.00 43.89  ? 590 TYR B O   1 
ATOM   8735  C CB  . TYR B 1 590 ? 123.418 116.638 168.054 1.00 36.79  ? 590 TYR B CB  1 
ATOM   8736  C CG  . TYR B 1 590 ? 124.617 117.268 167.382 1.00 36.66  ? 590 TYR B CG  1 
ATOM   8737  C CD1 . TYR B 1 590 ? 124.415 118.294 166.445 1.00 38.44  ? 590 TYR B CD1 1 
ATOM   8738  C CD2 . TYR B 1 590 ? 125.925 116.885 167.727 1.00 38.44  ? 590 TYR B CD2 1 
ATOM   8739  C CE1 . TYR B 1 590 ? 125.507 118.942 165.854 1.00 35.87  ? 590 TYR B CE1 1 
ATOM   8740  C CE2 . TYR B 1 590 ? 127.025 117.539 167.148 1.00 40.32  ? 590 TYR B CE2 1 
ATOM   8741  C CZ  . TYR B 1 590 ? 126.816 118.574 166.216 1.00 39.25  ? 590 TYR B CZ  1 
ATOM   8742  O OH  . TYR B 1 590 ? 127.865 119.249 165.690 1.00 47.47  ? 590 TYR B OH  1 
ATOM   8743  N N   . ARG B 1 591 ? 120.721 117.750 170.476 1.00 39.79  ? 591 ARG B N   1 
ATOM   8744  C CA  . ARG B 1 591 ? 119.651 117.259 171.347 1.00 40.13  ? 591 ARG B CA  1 
ATOM   8745  C C   . ARG B 1 591 ? 118.317 116.990 170.631 1.00 39.55  ? 591 ARG B C   1 
ATOM   8746  O O   . ARG B 1 591 ? 117.494 116.218 171.119 1.00 44.83  ? 591 ARG B O   1 
ATOM   8747  C CB  . ARG B 1 591 ? 119.449 118.287 172.453 1.00 39.14  ? 591 ARG B CB  1 
ATOM   8748  N N   . SER B 1 592 ? 118.083 117.610 169.477 1.00 32.75  ? 592 SER B N   1 
ATOM   8749  C CA  . SER B 1 592 ? 116.848 117.522 168.695 1.00 32.74  ? 592 SER B CA  1 
ATOM   8750  C C   . SER B 1 592 ? 117.134 117.698 167.207 1.00 33.88  ? 592 SER B C   1 
ATOM   8751  O O   . SER B 1 592 ? 118.216 118.145 166.828 1.00 39.31  ? 592 SER B O   1 
ATOM   8752  C CB  . SER B 1 592 ? 115.817 118.545 169.197 1.00 40.07  ? 592 SER B CB  1 
ATOM   8753  O OG  . SER B 1 592 ? 116.150 119.871 168.830 1.00 40.96  ? 592 SER B OG  1 
ATOM   8754  N N   . ILE B 1 593 ? 116.190 117.336 166.332 1.00 32.70  ? 593 ILE B N   1 
ATOM   8755  C CA  . ILE B 1 593 ? 116.361 117.503 164.883 1.00 27.61  ? 593 ILE B CA  1 
ATOM   8756  C C   . ILE B 1 593 ? 116.483 118.982 164.506 1.00 33.02  ? 593 ILE B C   1 
ATOM   8757  O O   . ILE B 1 593 ? 117.294 119.305 163.644 1.00 37.29  ? 593 ILE B O   1 
ATOM   8758  C CB  . ILE B 1 593 ? 115.233 116.800 164.093 1.00 33.30  ? 593 ILE B CB  1 
ATOM   8759  C CG1 . ILE B 1 593 ? 115.161 115.287 164.370 1.00 34.25  ? 593 ILE B CG1 1 
ATOM   8760  C CG2 . ILE B 1 593 ? 115.361 117.034 162.576 1.00 29.16  ? 593 ILE B CG2 1 
ATOM   8761  C CD1 . ILE B 1 593 ? 116.428 114.505 164.036 1.00 34.18  ? 593 ILE B CD1 1 
ATOM   8762  N N   . LEU B 1 594 ? 115.760 119.897 165.161 1.00 36.49  ? 594 LEU B N   1 
ATOM   8763  C CA  . LEU B 1 594 ? 115.900 121.340 164.928 1.00 31.29  ? 594 LEU B CA  1 
ATOM   8764  C C   . LEU B 1 594 ? 117.288 121.841 165.344 1.00 30.72  ? 594 LEU B C   1 
ATOM   8765  O O   . LEU B 1 594 ? 117.934 122.543 164.579 1.00 37.09  ? 594 LEU B O   1 
ATOM   8766  C CB  . LEU B 1 594 ? 114.771 122.100 165.648 1.00 38.53  ? 594 LEU B CB  1 
ATOM   8767  C CG  . LEU B 1 594 ? 114.867 123.639 165.551 1.00 41.12  ? 594 LEU B CG  1 
ATOM   8768  C CD1 . LEU B 1 594 ? 114.782 124.142 164.114 1.00 38.84  ? 594 LEU B CD1 1 
ATOM   8769  C CD2 . LEU B 1 594 ? 113.741 124.284 166.343 1.00 35.80  ? 594 LEU B CD2 1 
ATOM   8770  N N   . ASP B 1 595 ? 117.772 121.429 166.515 1.00 27.66  ? 595 ASP B N   1 
ATOM   8771  C CA  . ASP B 1 595 ? 119.105 121.764 167.009 1.00 27.82  ? 595 ASP B CA  1 
ATOM   8772  C C   . ASP B 1 595 ? 120.200 121.313 166.028 1.00 31.34  ? 595 ASP B C   1 
ATOM   8773  O O   . ASP B 1 595 ? 120.989 122.128 165.559 1.00 36.15  ? 595 ASP B O   1 
ATOM   8774  C CB  . ASP B 1 595 ? 119.274 121.113 168.391 1.00 33.90  ? 595 ASP B CB  1 
ATOM   8775  C CG  . ASP B 1 595 ? 120.612 121.395 169.070 1.00 42.60  ? 595 ASP B CG  1 
ATOM   8776  O OD1 . ASP B 1 595 ? 121.070 122.555 169.049 1.00 43.02  ? 595 ASP B OD1 1 
ATOM   8777  O OD2 . ASP B 1 595 ? 121.169 120.450 169.672 1.00 43.44  ? 595 ASP B OD2 1 
ATOM   8778  N N   . ALA B 1 596 ? 120.205 120.040 165.632 1.00 30.10  ? 596 ALA B N   1 
ATOM   8779  C CA  . ALA B 1 596 ? 121.182 119.512 164.692 1.00 19.23  ? 596 ALA B CA  1 
ATOM   8780  C C   . ALA B 1 596 ? 121.044 120.078 163.275 1.00 24.64  ? 596 ALA B C   1 
ATOM   8781  O O   . ALA B 1 596 ? 122.050 120.327 162.627 1.00 31.15  ? 596 ALA B O   1 
ATOM   8782  C CB  . ALA B 1 596 ? 121.089 117.987 164.702 1.00 24.65  ? 596 ALA B CB  1 
ATOM   8783  N N   . SER B 1 597 ? 119.827 120.341 162.792 1.00 28.40  ? 597 SER B N   1 
ATOM   8784  C CA  . SER B 1 597 ? 119.620 120.994 161.493 1.00 19.72  ? 597 SER B CA  1 
ATOM   8785  C C   . SER B 1 597 ? 120.189 122.404 161.477 1.00 21.65  ? 597 SER B C   1 
ATOM   8786  O O   . SER B 1 597 ? 120.773 122.810 160.484 1.00 30.35  ? 597 SER B O   1 
ATOM   8787  C CB  . SER B 1 597 ? 118.142 121.093 161.131 1.00 23.46  ? 597 SER B CB  1 
ATOM   8788  O OG  . SER B 1 597 ? 117.570 119.815 161.056 1.00 35.54  ? 597 SER B OG  1 
ATOM   8789  N N   . LEU B 1 598 ? 120.035 123.162 162.557 1.00 22.32  ? 598 LEU B N   1 
ATOM   8790  C CA  . LEU B 1 598 ? 120.546 124.522 162.626 1.00 21.00  ? 598 LEU B CA  1 
ATOM   8791  C C   . LEU B 1 598 ? 122.076 124.545 162.743 1.00 19.07  ? 598 LEU B C   1 
ATOM   8792  O O   . LEU B 1 598 ? 122.730 125.320 162.054 1.00 24.35  ? 598 LEU B O   1 
ATOM   8793  C CB  . LEU B 1 598 ? 119.815 125.257 163.757 1.00 26.83  ? 598 LEU B CB  1 
ATOM   8794  C CG  . LEU B 1 598 ? 119.942 126.781 163.671 1.00 30.36  ? 598 LEU B CG  1 
ATOM   8795  C CD1 . LEU B 1 598 ? 119.206 127.326 162.448 1.00 20.74  ? 598 LEU B CD1 1 
ATOM   8796  C CD2 . LEU B 1 598 ? 119.348 127.407 164.925 1.00 22.68  ? 598 LEU B CD2 1 
ATOM   8797  N N   . GLU B 1 599 ? 122.671 123.647 163.527 1.00 21.27  ? 599 GLU B N   1 
ATOM   8798  C CA  . GLU B 1 599 ? 124.123 123.453 163.562 1.00 14.57  ? 599 GLU B CA  1 
ATOM   8799  C C   . GLU B 1 599 ? 124.709 123.021 162.215 1.00 21.83  ? 599 GLU B C   1 
ATOM   8800  O O   . GLU B 1 599 ? 125.731 123.556 161.791 1.00 33.85  ? 599 GLU B O   1 
ATOM   8801  C CB  . GLU B 1 599 ? 124.494 122.419 164.636 1.00 25.85  ? 599 GLU B CB  1 
ATOM   8802  C CG  . GLU B 1 599 ? 124.298 122.898 166.080 1.00 24.81  ? 599 GLU B CG  1 
ATOM   8803  C CD  . GLU B 1 599 ? 124.995 124.228 166.389 1.00 36.56  ? 599 GLU B CD  1 
ATOM   8804  O OE1 . GLU B 1 599 ? 126.139 124.436 165.937 1.00 36.58  ? 599 GLU B OE1 1 
ATOM   8805  O OE2 . GLU B 1 599 ? 124.394 125.095 167.059 1.00 37.37  ? 599 GLU B OE2 1 
ATOM   8806  N N   . LEU B 1 600 ? 124.062 122.109 161.492 1.00 23.09  ? 600 LEU B N   1 
ATOM   8807  C CA  . LEU B 1 600 ? 124.477 121.737 160.146 1.00 7.60   ? 600 LEU B CA  1 
ATOM   8808  C C   . LEU B 1 600 ? 124.277 122.857 159.126 1.00 7.70   ? 600 LEU B C   1 
ATOM   8809  O O   . LEU B 1 600 ? 125.102 123.022 158.228 1.00 27.63  ? 600 LEU B O   1 
ATOM   8810  C CB  . LEU B 1 600 ? 123.722 120.484 159.698 1.00 20.99  ? 600 LEU B CB  1 
ATOM   8811  C CG  . LEU B 1 600 ? 124.170 119.176 160.358 1.00 7.03   ? 600 LEU B CG  1 
ATOM   8812  C CD1 . LEU B 1 600 ? 123.401 118.037 159.722 1.00 14.06  ? 600 LEU B CD1 1 
ATOM   8813  C CD2 . LEU B 1 600 ? 125.651 118.911 160.165 1.00 13.98  ? 600 LEU B CD2 1 
ATOM   8814  N N   . PHE B 1 601 ? 123.211 123.644 159.226 1.00 18.83  ? 601 PHE B N   1 
ATOM   8815  C CA  . PHE B 1 601 ? 122.985 124.778 158.341 1.00 16.41  ? 601 PHE B CA  1 
ATOM   8816  C C   . PHE B 1 601 ? 124.032 125.889 158.533 1.00 16.51  ? 601 PHE B C   1 
ATOM   8817  O O   . PHE B 1 601 ? 124.468 126.505 157.562 1.00 14.51  ? 601 PHE B O   1 
ATOM   8818  C CB  . PHE B 1 601 ? 121.553 125.294 158.519 1.00 14.10  ? 601 PHE B CB  1 
ATOM   8819  C CG  . PHE B 1 601 ? 121.235 126.433 157.577 1.00 17.13  ? 601 PHE B CG  1 
ATOM   8820  C CD1 . PHE B 1 601 ? 121.107 126.184 156.199 1.00 19.85  ? 601 PHE B CD1 1 
ATOM   8821  C CD2 . PHE B 1 601 ? 121.158 127.749 158.055 1.00 15.76  ? 601 PHE B CD2 1 
ATOM   8822  C CE1 . PHE B 1 601 ? 120.925 127.244 155.304 1.00 18.40  ? 601 PHE B CE1 1 
ATOM   8823  C CE2 . PHE B 1 601 ? 120.966 128.809 157.160 1.00 19.77  ? 601 PHE B CE2 1 
ATOM   8824  C CZ  . PHE B 1 601 ? 120.853 128.560 155.786 1.00 18.40  ? 601 PHE B CZ  1 
ATOM   8825  N N   . LYS B 1 602 ? 124.525 126.089 159.761 1.00 22.08  ? 602 LYS B N   1 
ATOM   8826  C CA  . LYS B 1 602 ? 125.562 127.076 160.077 1.00 9.24   ? 602 LYS B CA  1 
ATOM   8827  C C   . LYS B 1 602 ? 126.856 126.932 159.280 1.00 11.40  ? 602 LYS B C   1 
ATOM   8828  O O   . LYS B 1 602 ? 127.496 127.940 159.003 1.00 26.61  ? 602 LYS B O   1 
ATOM   8829  C CB  . LYS B 1 602 ? 125.815 127.128 161.590 1.00 8.83   ? 602 LYS B CB  1 
ATOM   8830  C CG  . LYS B 1 602 ? 124.790 128.078 162.214 1.00 13.86  ? 602 LYS B CG  1 
ATOM   8831  C CD  . LYS B 1 602 ? 125.032 128.387 163.688 1.00 17.19  ? 602 LYS B CD  1 
ATOM   8832  C CE  . LYS B 1 602 ? 124.666 127.220 164.591 1.00 13.84  ? 602 LYS B CE  1 
ATOM   8833  N NZ  . LYS B 1 602 ? 124.610 127.640 166.009 1.00 27.33  ? 602 LYS B NZ  1 
ATOM   8834  N N   . PHE B 1 603 ? 127.214 125.746 158.802 1.00 19.17  ? 603 PHE B N   1 
ATOM   8835  C CA  . PHE B 1 603 ? 128.340 125.570 157.884 1.00 19.97  ? 603 PHE B CA  1 
ATOM   8836  C C   . PHE B 1 603 ? 128.180 126.311 156.552 1.00 22.43  ? 603 PHE B C   1 
ATOM   8837  O O   . PHE B 1 603 ? 129.168 126.760 155.984 1.00 30.66  ? 603 PHE B O   1 
ATOM   8838  C CB  . PHE B 1 603 ? 128.567 124.082 157.628 1.00 9.82   ? 603 PHE B CB  1 
ATOM   8839  C CG  . PHE B 1 603 ? 129.135 123.354 158.818 1.00 14.63  ? 603 PHE B CG  1 
ATOM   8840  C CD1 . PHE B 1 603 ? 130.521 123.363 159.040 1.00 15.60  ? 603 PHE B CD1 1 
ATOM   8841  C CD2 . PHE B 1 603 ? 128.296 122.684 159.719 1.00 10.91  ? 603 PHE B CD2 1 
ATOM   8842  C CE1 . PHE B 1 603 ? 131.047 122.707 160.156 1.00 14.42  ? 603 PHE B CE1 1 
ATOM   8843  C CE2 . PHE B 1 603 ? 128.827 122.026 160.835 1.00 12.25  ? 603 PHE B CE2 1 
ATOM   8844  C CZ  . PHE B 1 603 ? 130.208 122.037 161.057 1.00 16.30  ? 603 PHE B CZ  1 
ATOM   8845  N N   . THR B 1 604 ? 126.959 126.494 156.055 1.00 26.75  ? 604 THR B N   1 
ATOM   8846  C CA  . THR B 1 604 ? 126.710 127.197 154.787 1.00 15.06  ? 604 THR B CA  1 
ATOM   8847  C C   . THR B 1 604 ? 126.864 128.718 154.894 1.00 13.86  ? 604 THR B C   1 
ATOM   8848  O O   . THR B 1 604 ? 127.095 129.380 153.889 1.00 28.67  ? 604 THR B O   1 
ATOM   8849  C CB  . THR B 1 604 ? 125.329 126.856 154.213 1.00 26.86  ? 604 THR B CB  1 
ATOM   8850  O OG1 . THR B 1 604 ? 124.300 127.417 154.987 1.00 32.71  ? 604 THR B OG1 1 
ATOM   8851  C CG2 . THR B 1 604 ? 125.088 125.353 154.116 1.00 23.28  ? 604 THR B CG2 1 
ATOM   8852  N N   . ILE B 1 605 ? 126.781 129.273 156.104 1.00 17.95  ? 605 ILE B N   1 
ATOM   8853  C CA  . ILE B 1 605 ? 126.909 130.706 156.392 1.00 15.20  ? 605 ILE B CA  1 
ATOM   8854  C C   . ILE B 1 605 ? 128.254 131.071 157.047 1.00 15.06  ? 605 ILE B C   1 
ATOM   8855  O O   . ILE B 1 605 ? 128.422 132.170 157.560 1.00 26.29  ? 605 ILE B O   1 
ATOM   8856  C CB  . ILE B 1 605 ? 125.687 131.232 157.172 1.00 11.53  ? 605 ILE B CB  1 
ATOM   8857  C CG1 . ILE B 1 605 ? 125.545 130.582 158.555 1.00 14.17  ? 605 ILE B CG1 1 
ATOM   8858  C CG2 . ILE B 1 605 ? 124.397 131.056 156.370 1.00 12.61  ? 605 ILE B CG2 1 
ATOM   8859  C CD1 . ILE B 1 605 ? 124.757 131.430 159.542 1.00 10.18  ? 605 ILE B CD1 1 
ATOM   8860  N N   . GLY B 1 606 ? 129.223 130.156 157.045 1.00 10.51  ? 606 GLY B N   1 
ATOM   8861  C CA  . GLY B 1 606 ? 130.553 130.376 157.607 1.00 0.00   ? 606 GLY B CA  1 
ATOM   8862  C C   . GLY B 1 606 ? 130.635 130.320 159.132 1.00 3.54   ? 606 GLY B C   1 
ATOM   8863  O O   . GLY B 1 606 ? 131.550 130.895 159.692 1.00 26.13  ? 606 GLY B O   1 
ATOM   8864  N N   . MET B 1 607 ? 129.700 129.649 159.807 1.00 15.85  ? 607 MET B N   1 
ATOM   8865  C CA  . MET B 1 607 ? 129.551 129.653 161.269 1.00 0.83   ? 607 MET B CA  1 
ATOM   8866  C C   . MET B 1 607 ? 129.535 128.265 161.926 1.00 13.35  ? 607 MET B C   1 
ATOM   8867  O O   . MET B 1 607 ? 129.193 128.140 163.097 1.00 15.20  ? 607 MET B O   1 
ATOM   8868  C CB  . MET B 1 607 ? 128.302 130.467 161.638 1.00 16.92  ? 607 MET B CB  1 
ATOM   8869  C CG  . MET B 1 607 ? 128.538 131.966 161.480 1.00 0.00   ? 607 MET B CG  1 
ATOM   8870  S SD  . MET B 1 607 ? 129.622 132.700 162.736 1.00 23.99  ? 607 MET B SD  1 
ATOM   8871  C CE  . MET B 1 607 ? 128.587 132.633 164.205 1.00 9.31   ? 607 MET B CE  1 
ATOM   8872  N N   . GLY B 1 608 ? 129.866 127.202 161.190 1.00 13.82  ? 608 GLY B N   1 
ATOM   8873  C CA  . GLY B 1 608 ? 129.759 125.824 161.665 1.00 5.67   ? 608 GLY B CA  1 
ATOM   8874  C C   . GLY B 1 608 ? 130.851 125.406 162.648 1.00 17.97  ? 608 GLY B C   1 
ATOM   8875  O O   . GLY B 1 608 ? 132.034 125.524 162.367 1.00 30.12  ? 608 GLY B O   1 
ATOM   8876  N N   . GLU B 1 609 ? 130.479 124.870 163.803 1.00 32.67  ? 609 GLU B N   1 
ATOM   8877  C CA  . GLU B 1 609 ? 131.440 124.389 164.797 1.00 28.62  ? 609 GLU B CA  1 
ATOM   8878  C C   . GLU B 1 609 ? 131.922 122.960 164.500 1.00 33.45  ? 609 GLU B C   1 
ATOM   8879  O O   . GLU B 1 609 ? 131.144 122.009 164.562 1.00 39.59  ? 609 GLU B O   1 
ATOM   8880  C CB  . GLU B 1 609 ? 130.836 124.489 166.204 1.00 31.73  ? 609 GLU B CB  1 
ATOM   8881  C CG  . GLU B 1 609 ? 130.647 125.933 166.699 1.00 36.83  ? 609 GLU B CG  1 
ATOM   8882  C CD  . GLU B 1 609 ? 131.950 126.660 167.082 1.00 47.46  ? 609 GLU B CD  1 
ATOM   8883  O OE1 . GLU B 1 609 ? 133.053 126.090 166.926 1.00 47.74  ? 609 GLU B OE1 1 
ATOM   8884  O OE2 . GLU B 1 609 ? 131.870 127.802 167.576 1.00 41.00  ? 609 GLU B OE2 1 
ATOM   8885  N N   . LEU B 1 610 ? 133.225 122.791 164.252 1.00 34.60  ? 610 LEU B N   1 
ATOM   8886  C CA  . LEU B 1 610 ? 133.911 121.496 164.303 1.00 27.87  ? 610 LEU B CA  1 
ATOM   8887  C C   . LEU B 1 610 ? 134.725 121.383 165.590 1.00 34.29  ? 610 LEU B C   1 
ATOM   8888  O O   . LEU B 1 610 ? 135.591 122.211 165.876 1.00 38.89  ? 610 LEU B O   1 
ATOM   8889  C CB  . LEU B 1 610 ? 134.877 121.305 163.127 1.00 28.23  ? 610 LEU B CB  1 
ATOM   8890  C CG  . LEU B 1 610 ? 134.244 121.202 161.746 1.00 32.26  ? 610 LEU B CG  1 
ATOM   8891  C CD1 . LEU B 1 610 ? 135.339 121.229 160.690 1.00 35.78  ? 610 LEU B CD1 1 
ATOM   8892  C CD2 . LEU B 1 610 ? 133.450 119.914 161.550 1.00 32.25  ? 610 LEU B CD2 1 
ATOM   8893  N N   . ALA B 1 611 ? 134.493 120.313 166.332 1.00 43.95  ? 611 ALA B N   1 
ATOM   8894  C CA  . ALA B 1 611 ? 135.276 119.953 167.499 1.00 42.09  ? 611 ALA B CA  1 
ATOM   8895  C C   . ALA B 1 611 ? 135.351 118.435 167.611 1.00 44.77  ? 611 ALA B C   1 
ATOM   8896  O O   . ALA B 1 611 ? 134.374 117.743 167.325 1.00 47.94  ? 611 ALA B O   1 
ATOM   8897  C CB  . ALA B 1 611 ? 134.618 120.577 168.732 1.00 39.91  ? 611 ALA B CB  1 
ATOM   8898  N N   . PHE B 1 612 ? 136.478 117.902 168.083 1.00 51.49  ? 612 PHE B N   1 
ATOM   8899  C CA  . PHE B 1 612 ? 136.520 116.551 168.629 1.00 49.69  ? 612 PHE B CA  1 
ATOM   8900  C C   . PHE B 1 612 ? 135.837 116.585 170.004 1.00 50.93  ? 612 PHE B C   1 
ATOM   8901  O O   . PHE B 1 612 ? 136.427 116.975 171.010 1.00 51.66  ? 612 PHE B O   1 
ATOM   8902  C CB  . PHE B 1 612 ? 137.971 116.069 168.654 1.00 49.42  ? 612 PHE B CB  1 
ATOM   8903  C CG  . PHE B 1 612 ? 138.129 114.613 169.023 1.00 52.15  ? 612 PHE B CG  1 
ATOM   8904  C CD1 . PHE B 1 612 ? 137.785 113.613 168.097 1.00 48.62  ? 612 PHE B CD1 1 
ATOM   8905  C CD2 . PHE B 1 612 ? 138.672 114.249 170.268 1.00 52.67  ? 612 PHE B CD2 1 
ATOM   8906  C CE1 . PHE B 1 612 ? 138.000 112.261 168.405 1.00 52.96  ? 612 PHE B CE1 1 
ATOM   8907  C CE2 . PHE B 1 612 ? 138.898 112.897 170.573 1.00 51.27  ? 612 PHE B CE2 1 
ATOM   8908  C CZ  . PHE B 1 612 ? 138.567 111.904 169.639 1.00 53.44  ? 612 PHE B CZ  1 
ATOM   8909  N N   . GLN B 1 613 ? 134.536 116.308 170.010 1.00 55.85  ? 613 GLN B N   1 
ATOM   8910  C CA  . GLN B 1 613 ? 133.622 116.660 171.096 1.00 56.87  ? 613 GLN B CA  1 
ATOM   8911  C C   . GLN B 1 613 ? 133.704 115.662 172.261 1.00 58.17  ? 613 GLN B C   1 
ATOM   8912  O O   . GLN B 1 613 ? 132.993 114.661 172.294 1.00 58.22  ? 613 GLN B O   1 
ATOM   8913  C CB  . GLN B 1 613 ? 132.224 116.803 170.476 1.00 54.32  ? 613 GLN B CB  1 
ATOM   8914  C CG  . GLN B 1 613 ? 131.234 117.524 171.394 1.00 55.43  ? 613 GLN B CG  1 
ATOM   8915  C CD  . GLN B 1 613 ? 130.130 118.237 170.619 1.00 59.42  ? 613 GLN B CD  1 
ATOM   8916  O OE1 . GLN B 1 613 ? 129.826 117.942 169.475 1.00 56.55  ? 613 GLN B OE1 1 
ATOM   8917  N NE2 . GLN B 1 613 ? 129.487 119.217 171.208 1.00 60.31  ? 613 GLN B NE2 1 
ATOM   8918  N N   . GLU B 1 614 ? 134.616 115.910 173.204 1.00 63.21  ? 614 GLU B N   1 
ATOM   8919  C CA  . GLU B 1 614 ? 135.125 114.894 174.139 1.00 61.27  ? 614 GLU B CA  1 
ATOM   8920  C C   . GLU B 1 614 ? 134.068 114.196 175.012 1.00 63.59  ? 614 GLU B C   1 
ATOM   8921  O O   . GLU B 1 614 ? 134.247 113.024 175.335 1.00 62.79  ? 614 GLU B O   1 
ATOM   8922  C CB  . GLU B 1 614 ? 136.220 115.483 175.037 1.00 60.87  ? 614 GLU B CB  1 
ATOM   8923  C CG  . GLU B 1 614 ? 137.506 115.835 174.275 1.00 60.22  ? 614 GLU B CG  1 
ATOM   8924  C CD  . GLU B 1 614 ? 138.765 115.775 175.162 1.00 64.79  ? 614 GLU B CD  1 
ATOM   8925  O OE1 . GLU B 1 614 ? 138.670 115.974 176.393 1.00 65.08  ? 614 GLU B OE1 1 
ATOM   8926  O OE2 . GLU B 1 614 ? 139.863 115.524 174.628 1.00 63.71  ? 614 GLU B OE2 1 
ATOM   8927  N N   . GLN B 1 615 ? 132.947 114.872 175.296 1.00 62.95  ? 615 GLN B N   1 
ATOM   8928  C CA  . GLN B 1 615 ? 131.909 114.325 176.225 1.00 59.32  ? 615 GLN B CA  1 
ATOM   8929  C C   . GLN B 1 615 ? 131.075 113.201 175.587 1.00 62.86  ? 615 GLN B C   1 
ATOM   8930  O O   . GLN B 1 615 ? 130.371 112.507 176.348 1.00 64.23  ? 615 GLN B O   1 
ATOM   8931  C CB  . GLN B 1 615 ? 131.013 115.471 176.711 1.00 61.20  ? 615 GLN B CB  1 
ATOM   8932  C CG  . GLN B 1 615 ? 130.117 116.085 175.620 1.00 61.61  ? 615 GLN B CG  1 
ATOM   8933  C CD  . GLN B 1 615 ? 129.208 117.162 176.160 1.00 64.79  ? 615 GLN B CD  1 
ATOM   8934  O OE1 . GLN B 1 615 ? 129.204 117.457 177.354 1.00 64.43  ? 615 GLN B OE1 1 
ATOM   8935  N NE2 . GLN B 1 615 ? 128.424 117.759 175.278 1.00 64.41  ? 615 GLN B NE2 1 
ATOM   8936  N N   . LEU B 1 616 ? 131.141 113.017 174.266 1.00 59.15  ? 616 LEU B N   1 
ATOM   8937  C CA  . LEU B 1 616 ? 130.361 112.002 173.554 1.00 53.20  ? 616 LEU B CA  1 
ATOM   8938  C C   . LEU B 1 616 ? 131.099 110.661 173.490 1.00 53.29  ? 616 LEU B C   1 
ATOM   8939  O O   . LEU B 1 616 ? 132.304 110.603 173.264 1.00 55.78  ? 616 LEU B O   1 
ATOM   8940  C CB  . LEU B 1 616 ? 130.007 112.497 172.140 1.00 55.45  ? 616 LEU B CB  1 
ATOM   8941  C CG  . LEU B 1 616 ? 129.159 113.769 172.064 1.00 55.14  ? 616 LEU B CG  1 
ATOM   8942  C CD1 . LEU B 1 616 ? 128.886 114.116 170.604 1.00 49.36  ? 616 LEU B CD1 1 
ATOM   8943  C CD2 . LEU B 1 616 ? 127.823 113.621 172.781 1.00 53.97  ? 616 LEU B CD2 1 
ATOM   8944  N N   . ARG B 1 617 ? 130.257 109.612 173.393 1.00 50.29  ? 617 ARG B N   1 
ATOM   8945  C CA  . ARG B 1 617 ? 130.742 108.257 173.041 1.00 48.29  ? 617 ARG B CA  1 
ATOM   8946  C C   . ARG B 1 617 ? 130.626 108.306 171.521 1.00 55.05  ? 617 ARG B C   1 
ATOM   8947  O O   . ARG B 1 617 ? 129.717 109.010 171.038 1.00 57.28  ? 617 ARG B O   1 
ATOM   8948  C CB  . ARG B 1 617 ? 129.802 107.206 173.629 1.00 50.25  ? 617 ARG B CB  1 
ATOM   8949  C CG  . ARG B 1 617 ? 130.274 105.753 173.533 1.00 48.10  ? 617 ARG B CG  1 
ATOM   8950  C CD  . ARG B 1 617 ? 129.192 104.887 174.183 1.00 53.85  ? 617 ARG B CD  1 
ATOM   8951  N NE  . ARG B 1 617 ? 129.525 103.472 174.244 1.00 55.88  ? 617 ARG B NE  1 
ATOM   8952  C CZ  . ARG B 1 617 ? 128.780 102.555 174.852 1.00 57.83  ? 617 ARG B CZ  1 
ATOM   8953  N NH1 . ARG B 1 617 ? 129.160 101.290 174.858 1.00 55.30  ? 617 ARG B NH1 1 
ATOM   8954  N NH2 . ARG B 1 617 ? 127.661 102.910 175.457 1.00 58.19  ? 617 ARG B NH2 1 
ATOM   8955  N N   . PHE B 1 618 ? 131.484 107.614 170.790 1.00 48.42  ? 618 PHE B N   1 
ATOM   8956  C CA  . PHE B 1 618 ? 131.540 107.705 169.321 1.00 46.14  ? 618 PHE B CA  1 
ATOM   8957  C C   . PHE B 1 618 ? 131.876 109.114 168.791 1.00 45.71  ? 618 PHE B C   1 
ATOM   8958  O O   . PHE B 1 618 ? 131.575 109.435 167.643 1.00 51.18  ? 618 PHE B O   1 
ATOM   8959  C CB  . PHE B 1 618 ? 130.281 107.107 168.665 1.00 40.68  ? 618 PHE B CB  1 
ATOM   8960  C CG  . PHE B 1 618 ? 129.772 105.820 169.270 1.00 39.63  ? 618 PHE B CG  1 
ATOM   8961  C CD1 . PHE B 1 618 ? 130.521 104.640 169.134 1.00 39.29  ? 618 PHE B CD1 1 
ATOM   8962  C CD2 . PHE B 1 618 ? 128.548 105.797 169.957 1.00 40.58  ? 618 PHE B CD2 1 
ATOM   8963  C CE1 . PHE B 1 618 ? 130.038 103.439 169.667 1.00 40.53  ? 618 PHE B CE1 1 
ATOM   8964  C CE2 . PHE B 1 618 ? 128.070 104.596 170.496 1.00 41.63  ? 618 PHE B CE2 1 
ATOM   8965  C CZ  . PHE B 1 618 ? 128.810 103.417 170.345 1.00 41.41  ? 618 PHE B CZ  1 
ATOM   8966  N N   . ARG B 1 619 ? 132.601 109.913 169.597 1.00 49.16  ? 619 ARG B N   1 
ATOM   8967  C CA  . ARG B 1 619 ? 132.987 111.318 169.231 1.00 46.22  ? 619 ARG B CA  1 
ATOM   8968  C C   . ARG B 1 619 ? 133.736 111.348 167.894 1.00 45.16  ? 619 ARG B C   1 
ATOM   8969  O O   . ARG B 1 619 ? 133.483 112.278 167.103 1.00 49.02  ? 619 ARG B O   1 
ATOM   8970  C CB  . ARG B 1 619 ? 133.730 111.955 170.420 1.00 49.60  ? 619 ARG B CB  1 
ATOM   8971  C CG  . ARG B 1 619 ? 134.983 111.192 170.872 1.00 47.42  ? 619 ARG B CG  1 
ATOM   8972  C CD  . ARG B 1 619 ? 135.556 111.837 172.132 1.00 53.03  ? 619 ARG B CD  1 
ATOM   8973  N NE  . ARG B 1 619 ? 136.850 111.260 172.467 1.00 55.32  ? 619 ARG B NE  1 
ATOM   8974  C CZ  . ARG B 1 619 ? 137.566 111.575 173.539 1.00 54.39  ? 619 ARG B CZ  1 
ATOM   8975  N NH1 . ARG B 1 619 ? 138.734 110.992 173.749 1.00 53.38  ? 619 ARG B NH1 1 
ATOM   8976  N NH2 . ARG B 1 619 ? 137.112 112.467 174.400 1.00 51.50  ? 619 ARG B NH2 1 
ATOM   8977  N N   . GLY B 1 620 ? 134.609 110.374 167.650 1.00 38.48  ? 620 GLY B N   1 
ATOM   8978  C CA  . GLY B 1 620 ? 135.354 110.271 166.395 1.00 36.24  ? 620 GLY B CA  1 
ATOM   8979  C C   . GLY B 1 620 ? 134.451 110.018 165.191 1.00 35.65  ? 620 GLY B C   1 
ATOM   8980  O O   . GLY B 1 620 ? 134.641 110.625 164.144 1.00 40.80  ? 620 GLY B O   1 
ATOM   8981  N N   . VAL B 1 621 ? 133.403 109.205 165.341 1.00 37.08  ? 621 VAL B N   1 
ATOM   8982  C CA  . VAL B 1 621 ? 132.394 108.985 164.297 1.00 35.81  ? 621 VAL B CA  1 
ATOM   8983  C C   . VAL B 1 621 ? 131.506 110.222 164.114 1.00 29.44  ? 621 VAL B C   1 
ATOM   8984  O O   . VAL B 1 621 ? 131.210 110.583 162.984 1.00 33.63  ? 621 VAL B O   1 
ATOM   8985  C CB  . VAL B 1 621 ? 131.558 107.723 164.572 1.00 35.39  ? 621 VAL B CB  1 
ATOM   8986  C CG1 . VAL B 1 621 ? 130.553 107.438 163.447 1.00 35.33  ? 621 VAL B CG1 1 
ATOM   8987  C CG2 . VAL B 1 621 ? 132.444 106.479 164.708 1.00 33.60  ? 621 VAL B CG2 1 
ATOM   8988  N N   . VAL B 1 622 ? 131.158 110.936 165.187 1.00 29.69  ? 622 VAL B N   1 
ATOM   8989  C CA  . VAL B 1 622 ? 130.463 112.234 165.117 1.00 24.91  ? 622 VAL B CA  1 
ATOM   8990  C C   . VAL B 1 622 ? 131.290 113.271 164.353 1.00 30.18  ? 622 VAL B C   1 
ATOM   8991  O O   . VAL B 1 622 ? 130.764 113.942 163.472 1.00 34.00  ? 622 VAL B O   1 
ATOM   8992  C CB  . VAL B 1 622 ? 130.080 112.718 166.528 1.00 25.76  ? 622 VAL B CB  1 
ATOM   8993  C CG1 . VAL B 1 622 ? 129.579 114.163 166.571 1.00 31.88  ? 622 VAL B CG1 1 
ATOM   8994  C CG2 . VAL B 1 622 ? 128.971 111.833 167.101 1.00 27.91  ? 622 VAL B CG2 1 
ATOM   8995  N N   . LEU B 1 623 ? 132.599 113.366 164.604 1.00 31.67  ? 623 LEU B N   1 
ATOM   8996  C CA  . LEU B 1 623 ? 133.487 114.232 163.838 1.00 24.31  ? 623 LEU B CA  1 
ATOM   8997  C C   . LEU B 1 623 ? 133.603 113.804 162.366 1.00 25.46  ? 623 LEU B C   1 
ATOM   8998  O O   . LEU B 1 623 ? 133.576 114.655 161.487 1.00 36.29  ? 623 LEU B O   1 
ATOM   8999  C CB  . LEU B 1 623 ? 134.859 114.307 164.532 1.00 32.22  ? 623 LEU B CB  1 
ATOM   9000  C CG  . LEU B 1 623 ? 135.866 115.223 163.811 1.00 33.08  ? 623 LEU B CG  1 
ATOM   9001  C CD1 . LEU B 1 623 ? 135.390 116.672 163.763 1.00 30.82  ? 623 LEU B CD1 1 
ATOM   9002  C CD2 . LEU B 1 623 ? 137.215 115.193 164.515 1.00 31.54  ? 623 LEU B CD2 1 
ATOM   9003  N N   . LEU B 1 624 ? 133.693 112.508 162.068 1.00 26.84  ? 624 LEU B N   1 
ATOM   9004  C CA  . LEU B 1 624 ? 133.706 112.019 160.691 1.00 23.45  ? 624 LEU B CA  1 
ATOM   9005  C C   . LEU B 1 624 ? 132.385 112.264 159.953 1.00 27.42  ? 624 LEU B C   1 
ATOM   9006  O O   . LEU B 1 624 ? 132.424 112.599 158.775 1.00 30.91  ? 624 LEU B O   1 
ATOM   9007  C CB  . LEU B 1 624 ? 134.082 110.529 160.663 1.00 33.65  ? 624 LEU B CB  1 
ATOM   9008  C CG  . LEU B 1 624 ? 135.552 110.247 161.006 1.00 36.55  ? 624 LEU B CG  1 
ATOM   9009  C CD1 . LEU B 1 624 ? 135.739 108.743 161.185 1.00 32.51  ? 624 LEU B CD1 1 
ATOM   9010  C CD2 . LEU B 1 624 ? 136.510 110.723 159.914 1.00 27.71  ? 624 LEU B CD2 1 
ATOM   9011  N N   . LEU B 1 625 ? 131.226 112.162 160.613 1.00 30.25  ? 625 LEU B N   1 
ATOM   9012  C CA  . LEU B 1 625 ? 129.939 112.580 160.052 1.00 19.89  ? 625 LEU B CA  1 
ATOM   9013  C C   . LEU B 1 625 ? 129.920 114.073 159.721 1.00 19.98  ? 625 LEU B C   1 
ATOM   9014  O O   . LEU B 1 625 ? 129.484 114.443 158.637 1.00 32.40  ? 625 LEU B O   1 
ATOM   9015  C CB  . LEU B 1 625 ? 128.786 112.262 161.023 1.00 30.12  ? 625 LEU B CB  1 
ATOM   9016  C CG  . LEU B 1 625 ? 128.372 110.789 161.101 1.00 28.72  ? 625 LEU B CG  1 
ATOM   9017  C CD1 . LEU B 1 625 ? 127.343 110.612 162.219 1.00 28.41  ? 625 LEU B CD1 1 
ATOM   9018  C CD2 . LEU B 1 625 ? 127.737 110.303 159.801 1.00 26.71  ? 625 LEU B CD2 1 
ATOM   9019  N N   . LEU B 1 626 ? 130.408 114.938 160.615 1.00 20.32  ? 626 LEU B N   1 
ATOM   9020  C CA  . LEU B 1 626 ? 130.512 116.371 160.350 1.00 19.10  ? 626 LEU B CA  1 
ATOM   9021  C C   . LEU B 1 626 ? 131.469 116.675 159.199 1.00 18.91  ? 626 LEU B C   1 
ATOM   9022  O O   . LEU B 1 626 ? 131.107 117.416 158.297 1.00 30.86  ? 626 LEU B O   1 
ATOM   9023  C CB  . LEU B 1 626 ? 130.950 117.118 161.615 1.00 28.01  ? 626 LEU B CB  1 
ATOM   9024  C CG  . LEU B 1 626 ? 129.871 117.198 162.696 1.00 22.99  ? 626 LEU B CG  1 
ATOM   9025  C CD1 . LEU B 1 626 ? 130.497 117.694 163.994 1.00 25.86  ? 626 LEU B CD1 1 
ATOM   9026  C CD2 . LEU B 1 626 ? 128.758 118.154 162.287 1.00 18.17  ? 626 LEU B CD2 1 
ATOM   9027  N N   . LEU B 1 627 ? 132.661 116.080 159.173 1.00 21.80  ? 627 LEU B N   1 
ATOM   9028  C CA  . LEU B 1 627 ? 133.599 116.253 158.070 1.00 17.73  ? 627 LEU B CA  1 
ATOM   9029  C C   . LEU B 1 627 ? 133.022 115.741 156.744 1.00 12.70  ? 627 LEU B C   1 
ATOM   9030  O O   . LEU B 1 627 ? 133.144 116.422 155.737 1.00 30.79  ? 627 LEU B O   1 
ATOM   9031  C CB  . LEU B 1 627 ? 134.945 115.587 158.401 1.00 22.68  ? 627 LEU B CB  1 
ATOM   9032  C CG  . LEU B 1 627 ? 135.743 116.284 159.519 1.00 25.55  ? 627 LEU B CG  1 
ATOM   9033  C CD1 . LEU B 1 627 ? 136.946 115.426 159.889 1.00 22.00  ? 627 LEU B CD1 1 
ATOM   9034  C CD2 . LEU B 1 627 ? 136.238 117.665 159.114 1.00 20.39  ? 627 LEU B CD2 1 
ATOM   9035  N N   . ALA B 1 628 ? 132.342 114.592 156.726 1.00 23.87  ? 628 ALA B N   1 
ATOM   9036  C CA  . ALA B 1 628 ? 131.632 114.107 155.548 1.00 9.93   ? 628 ALA B CA  1 
ATOM   9037  C C   . ALA B 1 628 ? 130.516 115.058 155.095 1.00 16.87  ? 628 ALA B C   1 
ATOM   9038  O O   . ALA B 1 628 ? 130.458 115.388 153.918 1.00 26.01  ? 628 ALA B O   1 
ATOM   9039  C CB  . ALA B 1 628 ? 131.093 112.707 155.822 1.00 19.84  ? 628 ALA B CB  1 
ATOM   9040  N N   . TYR B 1 629 ? 129.665 115.558 155.996 1.00 16.75  ? 629 TYR B N   1 
ATOM   9041  C CA  . TYR B 1 629 ? 128.652 116.546 155.653 1.00 6.28   ? 629 TYR B CA  1 
ATOM   9042  C C   . TYR B 1 629 ? 129.263 117.822 155.062 1.00 15.99  ? 629 TYR B C   1 
ATOM   9043  O O   . TYR B 1 629 ? 128.776 118.314 154.048 1.00 23.77  ? 629 TYR B O   1 
ATOM   9044  C CB  . TYR B 1 629 ? 127.793 116.875 156.880 1.00 5.28   ? 629 TYR B CB  1 
ATOM   9045  C CG  . TYR B 1 629 ? 126.899 118.079 156.682 1.00 15.81  ? 629 TYR B CG  1 
ATOM   9046  C CD1 . TYR B 1 629 ? 125.638 117.953 156.067 1.00 9.76   ? 629 TYR B CD1 1 
ATOM   9047  C CD2 . TYR B 1 629 ? 127.382 119.351 157.042 1.00 17.01  ? 629 TYR B CD2 1 
ATOM   9048  C CE1 . TYR B 1 629 ? 124.855 119.096 155.833 1.00 5.27   ? 629 TYR B CE1 1 
ATOM   9049  C CE2 . TYR B 1 629 ? 126.606 120.487 156.803 1.00 7.54   ? 629 TYR B CE2 1 
ATOM   9050  C CZ  . TYR B 1 629 ? 125.343 120.368 156.194 1.00 15.97  ? 629 TYR B CZ  1 
ATOM   9051  O OH  . TYR B 1 629 ? 124.594 121.482 156.022 1.00 29.31  ? 629 TYR B OH  1 
ATOM   9052  N N   . VAL B 1 630 ? 130.336 118.359 155.648 1.00 17.51  ? 630 VAL B N   1 
ATOM   9053  C CA  . VAL B 1 630 ? 131.020 119.557 155.146 1.00 18.70  ? 630 VAL B CA  1 
ATOM   9054  C C   . VAL B 1 630 ? 131.559 119.333 153.740 1.00 18.25  ? 630 VAL B C   1 
ATOM   9055  O O   . VAL B 1 630 ? 131.262 120.113 152.839 1.00 28.99  ? 630 VAL B O   1 
ATOM   9056  C CB  . VAL B 1 630 ? 132.140 119.985 156.109 1.00 26.54  ? 630 VAL B CB  1 
ATOM   9057  C CG1 . VAL B 1 630 ? 133.081 121.031 155.510 1.00 26.33  ? 630 VAL B CG1 1 
ATOM   9058  C CG2 . VAL B 1 630 ? 131.539 120.589 157.375 1.00 11.69  ? 630 VAL B CG2 1 
ATOM   9059  N N   . LEU B 1 631 ? 132.302 118.251 153.516 1.00 19.24  ? 631 LEU B N   1 
ATOM   9060  C CA  . LEU B 1 631 ? 132.872 117.939 152.211 1.00 12.55  ? 631 LEU B CA  1 
ATOM   9061  C C   . LEU B 1 631 ? 131.790 117.672 151.152 1.00 23.87  ? 631 LEU B C   1 
ATOM   9062  O O   . LEU B 1 631 ? 131.875 118.211 150.057 1.00 33.83  ? 631 LEU B O   1 
ATOM   9063  C CB  . LEU B 1 631 ? 133.853 116.768 152.353 1.00 23.19  ? 631 LEU B CB  1 
ATOM   9064  C CG  . LEU B 1 631 ? 135.093 117.083 153.215 1.00 27.07  ? 631 LEU B CG  1 
ATOM   9065  C CD1 . LEU B 1 631 ? 135.873 115.801 153.478 1.00 25.75  ? 631 LEU B CD1 1 
ATOM   9066  C CD2 . LEU B 1 631 ? 136.026 118.093 152.553 1.00 22.48  ? 631 LEU B CD2 1 
ATOM   9067  N N   . LEU B 1 632 ? 130.729 116.926 151.467 1.00 18.97  ? 632 LEU B N   1 
ATOM   9068  C CA  . LEU B 1 632 ? 129.591 116.728 150.562 1.00 11.83  ? 632 LEU B CA  1 
ATOM   9069  C C   . LEU B 1 632 ? 128.855 118.028 150.244 1.00 8.93   ? 632 LEU B C   1 
ATOM   9070  O O   . LEU B 1 632 ? 128.518 118.290 149.098 1.00 29.87  ? 632 LEU B O   1 
ATOM   9071  C CB  . LEU B 1 632 ? 128.606 115.728 151.183 1.00 23.81  ? 632 LEU B CB  1 
ATOM   9072  C CG  . LEU B 1 632 ? 129.119 114.285 151.240 1.00 22.99  ? 632 LEU B CG  1 
ATOM   9073  C CD1 . LEU B 1 632 ? 128.179 113.428 152.068 1.00 20.41  ? 632 LEU B CD1 1 
ATOM   9074  C CD2 . LEU B 1 632 ? 129.203 113.670 149.856 1.00 18.01  ? 632 LEU B CD2 1 
ATOM   9075  N N   . THR B 1 633 ? 128.627 118.874 151.244 1.00 27.45  ? 633 THR B N   1 
ATOM   9076  C CA  . THR B 1 633 ? 127.940 120.159 151.080 1.00 18.98  ? 633 THR B CA  1 
ATOM   9077  C C   . THR B 1 633 ? 128.766 121.134 150.251 1.00 14.74  ? 633 THR B C   1 
ATOM   9078  O O   . THR B 1 633 ? 128.216 121.839 149.416 1.00 28.45  ? 633 THR B O   1 
ATOM   9079  C CB  . THR B 1 633 ? 127.608 120.746 152.454 1.00 17.84  ? 633 THR B CB  1 
ATOM   9080  O OG1 . THR B 1 633 ? 126.758 119.851 153.106 1.00 23.68  ? 633 THR B OG1 1 
ATOM   9081  C CG2 . THR B 1 633 ? 126.893 122.088 152.418 1.00 24.95  ? 633 THR B CG2 1 
ATOM   9082  N N   . TYR B 1 634 ? 130.085 121.154 150.412 1.00 20.58  ? 634 TYR B N   1 
ATOM   9083  C CA  . TYR B 1 634 ? 130.969 122.010 149.627 1.00 15.36  ? 634 TYR B CA  1 
ATOM   9084  C C   . TYR B 1 634 ? 131.101 121.514 148.180 1.00 20.26  ? 634 TYR B C   1 
ATOM   9085  O O   . TYR B 1 634 ? 131.104 122.339 147.270 1.00 29.47  ? 634 TYR B O   1 
ATOM   9086  C CB  . TYR B 1 634 ? 132.330 122.191 150.303 1.00 22.68  ? 634 TYR B CB  1 
ATOM   9087  C CG  . TYR B 1 634 ? 132.293 123.205 151.419 1.00 33.91  ? 634 TYR B CG  1 
ATOM   9088  C CD1 . TYR B 1 634 ? 131.137 123.390 152.163 1.00 36.83  ? 634 TYR B CD1 1 
ATOM   9089  C CD2 . TYR B 1 634 ? 133.390 123.989 151.731 1.00 30.24  ? 634 TYR B CD2 1 
ATOM   9090  C CE1 . TYR B 1 634 ? 131.068 124.316 153.187 1.00 25.80  ? 634 TYR B CE1 1 
ATOM   9091  C CE2 . TYR B 1 634 ? 133.340 124.925 152.752 1.00 26.82  ? 634 TYR B CE2 1 
ATOM   9092  C CZ  . TYR B 1 634 ? 132.174 125.088 153.481 1.00 30.48  ? 634 TYR B CZ  1 
ATOM   9093  O OH  . TYR B 1 634 ? 132.101 126.000 154.491 1.00 37.21  ? 634 TYR B OH  1 
ATOM   9094  N N   . VAL B 1 635 ? 131.116 120.197 147.951 1.00 24.04  ? 635 VAL B N   1 
ATOM   9095  C CA  . VAL B 1 635 ? 130.981 119.596 146.621 1.00 18.90  ? 635 VAL B CA  1 
ATOM   9096  C C   . VAL B 1 635 ? 129.641 119.979 145.990 1.00 17.54  ? 635 VAL B C   1 
ATOM   9097  O O   . VAL B 1 635 ? 129.623 120.415 144.847 1.00 27.82  ? 635 VAL B O   1 
ATOM   9098  C CB  . VAL B 1 635 ? 131.145 118.066 146.682 1.00 24.50  ? 635 VAL B CB  1 
ATOM   9099  C CG1 . VAL B 1 635 ? 130.818 117.365 145.359 1.00 24.17  ? 635 VAL B CG1 1 
ATOM   9100  C CG2 . VAL B 1 635 ? 132.570 117.653 147.025 1.00 24.95  ? 635 VAL B CG2 1 
ATOM   9101  N N   . LEU B 1 636 ? 128.519 119.872 146.706 1.00 15.80  ? 636 LEU B N   1 
ATOM   9102  C CA  . LEU B 1 636 ? 127.200 120.267 146.212 1.00 12.37  ? 636 LEU B CA  1 
ATOM   9103  C C   . LEU B 1 636 ? 127.096 121.767 145.903 1.00 18.40  ? 636 LEU B C   1 
ATOM   9104  O O   . LEU B 1 636 ? 126.605 122.123 144.841 1.00 31.14  ? 636 LEU B O   1 
ATOM   9105  C CB  . LEU B 1 636 ? 126.143 119.819 147.236 1.00 23.96  ? 636 LEU B CB  1 
ATOM   9106  C CG  . LEU B 1 636 ? 124.707 120.287 146.930 1.00 28.74  ? 636 LEU B CG  1 
ATOM   9107  C CD1 . LEU B 1 636 ? 124.130 119.600 145.702 1.00 26.57  ? 636 LEU B CD1 1 
ATOM   9108  C CD2 . LEU B 1 636 ? 123.800 119.996 148.117 1.00 30.03  ? 636 LEU B CD2 1 
ATOM   9109  N N   . LEU B 1 637 ? 127.560 122.649 146.790 1.00 18.86  ? 637 LEU B N   1 
ATOM   9110  C CA  . LEU B 1 637 ? 127.528 124.096 146.580 1.00 14.46  ? 637 LEU B CA  1 
ATOM   9111  C C   . LEU B 1 637 ? 128.417 124.513 145.409 1.00 20.10  ? 637 LEU B C   1 
ATOM   9112  O O   . LEU B 1 637 ? 128.003 125.301 144.572 1.00 23.17  ? 637 LEU B O   1 
ATOM   9113  C CB  . LEU B 1 637 ? 127.944 124.823 147.869 1.00 24.62  ? 637 LEU B CB  1 
ATOM   9114  C CG  . LEU B 1 637 ? 126.883 124.781 148.987 1.00 28.24  ? 637 LEU B CG  1 
ATOM   9115  C CD1 . LEU B 1 637 ? 127.495 125.263 150.302 1.00 25.87  ? 637 LEU B CD1 1 
ATOM   9116  C CD2 . LEU B 1 637 ? 125.686 125.669 148.671 1.00 23.64  ? 637 LEU B CD2 1 
ATOM   9117  N N   . LEU B 1 638 ? 129.610 123.945 145.295 1.00 22.53  ? 638 LEU B N   1 
ATOM   9118  C CA  . LEU B 1 638 ? 130.519 124.201 144.189 1.00 18.92  ? 638 LEU B CA  1 
ATOM   9119  C C   . LEU B 1 638 ? 129.959 123.715 142.848 1.00 15.03  ? 638 LEU B C   1 
ATOM   9120  O O   . LEU B 1 638 ? 129.986 124.445 141.869 1.00 29.96  ? 638 LEU B O   1 
ATOM   9121  C CB  . LEU B 1 638 ? 131.856 123.551 144.560 1.00 25.88  ? 638 LEU B CB  1 
ATOM   9122  C CG  . LEU B 1 638 ? 132.976 123.679 143.531 1.00 21.05  ? 638 LEU B CG  1 
ATOM   9123  C CD1 . LEU B 1 638 ? 133.223 125.117 143.112 1.00 22.24  ? 638 LEU B CD1 1 
ATOM   9124  C CD2 . LEU B 1 638 ? 134.249 123.126 144.154 1.00 17.90  ? 638 LEU B CD2 1 
ATOM   9125  N N   . ASN B 1 639 ? 129.373 122.521 142.810 1.00 24.10  ? 639 ASN B N   1 
ATOM   9126  C CA  . ASN B 1 639 ? 128.636 122.019 141.654 1.00 18.52  ? 639 ASN B CA  1 
ATOM   9127  C C   . ASN B 1 639 ? 127.442 122.916 141.281 1.00 18.20  ? 639 ASN B C   1 
ATOM   9128  O O   . ASN B 1 639 ? 127.276 123.252 140.118 1.00 23.90  ? 639 ASN B O   1 
ATOM   9129  C CB  . ASN B 1 639 ? 128.166 120.595 141.953 1.00 19.15  ? 639 ASN B CB  1 
ATOM   9130  C CG  . ASN B 1 639 ? 129.161 119.529 141.545 1.00 24.18  ? 639 ASN B CG  1 
ATOM   9131  O OD1 . ASN B 1 639 ? 129.399 119.267 140.384 1.00 31.22  ? 639 ASN B OD1 1 
ATOM   9132  N ND2 . ASN B 1 639 ? 129.789 118.869 142.477 1.00 30.95  ? 639 ASN B ND2 1 
ATOM   9133  N N   . MET B 1 640 ? 126.637 123.348 142.247 1.00 25.09  ? 640 MET B N   1 
ATOM   9134  C CA  . MET B 1 640 ? 125.517 124.262 142.041 1.00 18.01  ? 640 MET B CA  1 
ATOM   9135  C C   . MET B 1 640 ? 125.955 125.615 141.471 1.00 21.18  ? 640 MET B C   1 
ATOM   9136  O O   . MET B 1 640 ? 125.364 126.089 140.508 1.00 31.21  ? 640 MET B O   1 
ATOM   9137  C CB  . MET B 1 640 ? 124.764 124.398 143.372 1.00 24.23  ? 640 MET B CB  1 
ATOM   9138  C CG  . MET B 1 640 ? 123.529 125.300 143.328 1.00 26.88  ? 640 MET B CG  1 
ATOM   9139  S SD  . MET B 1 640 ? 123.756 127.057 143.657 1.00 40.73  ? 640 MET B SD  1 
ATOM   9140  C CE  . MET B 1 640 ? 124.223 127.042 145.399 1.00 27.25  ? 640 MET B CE  1 
ATOM   9141  N N   . LEU B 1 641 ? 127.020 126.218 142.001 1.00 24.58  ? 641 LEU B N   1 
ATOM   9142  C CA  . LEU B 1 641 ? 127.550 127.492 141.510 1.00 21.40  ? 641 LEU B CA  1 
ATOM   9143  C C   . LEU B 1 641 ? 128.110 127.381 140.091 1.00 19.67  ? 641 LEU B C   1 
ATOM   9144  O O   . LEU B 1 641 ? 127.808 128.215 139.247 1.00 26.59  ? 641 LEU B O   1 
ATOM   9145  C CB  . LEU B 1 641 ? 128.617 128.018 142.484 1.00 26.34  ? 641 LEU B CB  1 
ATOM   9146  C CG  . LEU B 1 641 ? 128.056 128.465 143.844 1.00 30.82  ? 641 LEU B CG  1 
ATOM   9147  C CD1 . LEU B 1 641 ? 129.194 128.731 144.820 1.00 27.86  ? 641 LEU B CD1 1 
ATOM   9148  C CD2 . LEU B 1 641 ? 127.210 129.722 143.730 1.00 24.89  ? 641 LEU B CD2 1 
ATOM   9149  N N   . ILE B 1 642 ? 128.894 126.347 139.805 1.00 24.89  ? 642 ILE B N   1 
ATOM   9150  C CA  . ILE B 1 642 ? 129.425 126.099 138.465 1.00 19.62  ? 642 ILE B CA  1 
ATOM   9151  C C   . ILE B 1 642 ? 128.294 125.800 137.467 1.00 19.82  ? 642 ILE B C   1 
ATOM   9152  O O   . ILE B 1 642 ? 128.290 126.360 136.374 1.00 32.42  ? 642 ILE B O   1 
ATOM   9153  C CB  . ILE B 1 642 ? 130.486 124.982 138.543 1.00 27.53  ? 642 ILE B CB  1 
ATOM   9154  C CG1 . ILE B 1 642 ? 131.789 125.436 139.241 1.00 21.68  ? 642 ILE B CG1 1 
ATOM   9155  C CG2 . ILE B 1 642 ? 130.807 124.421 137.162 1.00 26.55  ? 642 ILE B CG2 1 
ATOM   9156  C CD1 . ILE B 1 642 ? 132.628 126.483 138.506 1.00 23.53  ? 642 ILE B CD1 1 
ATOM   9157  N N   . ALA B 1 643 ? 127.287 125.007 137.834 1.00 23.64  ? 643 ALA B N   1 
ATOM   9158  C CA  . ALA B 1 643 ? 126.116 124.774 136.997 1.00 12.63  ? 643 ALA B CA  1 
ATOM   9159  C C   . ALA B 1 643 ? 125.287 126.047 136.741 1.00 18.95  ? 643 ALA B C   1 
ATOM   9160  O O   . ALA B 1 643 ? 124.782 126.217 135.637 1.00 35.66  ? 643 ALA B O   1 
ATOM   9161  C CB  . ALA B 1 643 ? 125.270 123.664 137.626 1.00 21.55  ? 643 ALA B CB  1 
ATOM   9162  N N   . LEU B 1 644 ? 125.175 126.979 137.696 1.00 30.99  ? 644 LEU B N   1 
ATOM   9163  C CA  . LEU B 1 644 ? 124.586 128.298 137.438 1.00 24.98  ? 644 LEU B CA  1 
ATOM   9164  C C   . LEU B 1 644 ? 125.414 129.124 136.461 1.00 24.51  ? 644 LEU B C   1 
ATOM   9165  O O   . LEU B 1 644 ? 124.837 129.724 135.563 1.00 34.03  ? 644 LEU B O   1 
ATOM   9166  C CB  . LEU B 1 644 ? 124.408 129.096 138.735 1.00 26.64  ? 644 LEU B CB  1 
ATOM   9167  C CG  . LEU B 1 644 ? 123.249 128.640 139.622 1.00 31.14  ? 644 LEU B CG  1 
ATOM   9168  C CD1 . LEU B 1 644 ? 123.274 129.474 140.894 1.00 27.84  ? 644 LEU B CD1 1 
ATOM   9169  C CD2 . LEU B 1 644 ? 121.890 128.840 138.955 1.00 34.04  ? 644 LEU B CD2 1 
ATOM   9170  N N   . MET B 1 645 ? 126.742 129.165 136.578 1.00 32.70  ? 645 MET B N   1 
ATOM   9171  C CA  . MET B 1 645 ? 127.593 129.882 135.623 1.00 28.86  ? 645 MET B CA  1 
ATOM   9172  C C   . MET B 1 645 ? 127.448 129.338 134.198 1.00 31.61  ? 645 MET B C   1 
ATOM   9173  O O   . MET B 1 645 ? 127.216 130.120 133.283 1.00 37.35  ? 645 MET B O   1 
ATOM   9174  C CB  . MET B 1 645 ? 129.056 129.842 136.055 1.00 29.17  ? 645 MET B CB  1 
ATOM   9175  C CG  . MET B 1 645 ? 129.297 130.650 137.322 1.00 32.65  ? 645 MET B CG  1 
ATOM   9176  S SD  . MET B 1 645 ? 130.959 130.450 137.997 1.00 52.21  ? 645 MET B SD  1 
ATOM   9177  C CE  . MET B 1 645 ? 130.616 130.954 139.700 1.00 37.43  ? 645 MET B CE  1 
ATOM   9178  N N   . SER B 1 646 ? 127.487 128.015 134.002 1.00 33.02  ? 646 SER B N   1 
ATOM   9179  C CA  . SER B 1 646 ? 127.281 127.375 132.697 1.00 32.03  ? 646 SER B CA  1 
ATOM   9180  C C   . SER B 1 646 ? 125.929 127.717 132.059 1.00 37.47  ? 646 SER B C   1 
ATOM   9181  O O   . SER B 1 646 ? 125.818 127.761 130.840 1.00 45.37  ? 646 SER B O   1 
ATOM   9182  C CB  . SER B 1 646 ? 127.365 125.850 132.816 1.00 27.85  ? 646 SER B CB  1 
ATOM   9183  O OG  . SER B 1 646 ? 128.590 125.428 133.374 1.00 36.36  ? 646 SER B OG  1 
ATOM   9184  N N   . GLU B 1 647 ? 124.885 127.956 132.846 1.00 36.15  ? 647 GLU B N   1 
ATOM   9185  C CA  . GLU B 1 647 ? 123.559 128.307 132.332 1.00 36.22  ? 647 GLU B CA  1 
ATOM   9186  C C   . GLU B 1 647 ? 123.374 129.817 132.088 1.00 39.21  ? 647 GLU B C   1 
ATOM   9187  O O   . GLU B 1 647 ? 122.660 130.220 131.174 1.00 44.20  ? 647 GLU B O   1 
ATOM   9188  C CB  . GLU B 1 647 ? 122.512 127.764 133.313 1.00 35.63  ? 647 GLU B CB  1 
ATOM   9189  C CG  . GLU B 1 647 ? 121.049 127.995 132.907 1.00 45.33  ? 647 GLU B CG  1 
ATOM   9190  C CD  . GLU B 1 647 ? 120.544 127.085 131.772 1.00 50.47  ? 647 GLU B CD  1 
ATOM   9191  O OE1 . GLU B 1 647 ? 121.287 126.813 130.803 1.00 50.08  ? 647 GLU B OE1 1 
ATOM   9192  O OE2 . GLU B 1 647 ? 119.381 126.636 131.858 1.00 47.95  ? 647 GLU B OE2 1 
ATOM   9193  N N   . THR B 1 648 ? 124.005 130.668 132.898 1.00 35.61  ? 648 THR B N   1 
ATOM   9194  C CA  . THR B 1 648 ? 123.697 132.106 132.959 1.00 34.31  ? 648 THR B CA  1 
ATOM   9195  C C   . THR B 1 648 ? 124.731 133.025 132.305 1.00 35.08  ? 648 THR B C   1 
ATOM   9196  O O   . THR B 1 648 ? 124.375 134.142 131.935 1.00 40.24  ? 648 THR B O   1 
ATOM   9197  C CB  . THR B 1 648 ? 123.465 132.556 134.411 1.00 36.55  ? 648 THR B CB  1 
ATOM   9198  O OG1 . THR B 1 648 ? 124.592 132.308 135.203 1.00 40.46  ? 648 THR B OG1 1 
ATOM   9199  C CG2 . THR B 1 648 ? 122.259 131.904 135.084 1.00 28.28  ? 648 THR B CG2 1 
ATOM   9200  N N   . VAL B 1 649 ? 125.985 132.599 132.131 1.00 36.00  ? 649 VAL B N   1 
ATOM   9201  C CA  . VAL B 1 649 ? 127.105 133.440 131.657 1.00 38.52  ? 649 VAL B CA  1 
ATOM   9202  C C   . VAL B 1 649 ? 127.514 133.029 130.232 1.00 38.34  ? 649 VAL B C   1 
ATOM   9203  O O   . VAL B 1 649 ? 128.612 132.548 129.988 1.00 40.52  ? 649 VAL B O   1 
ATOM   9204  C CB  . VAL B 1 649 ? 128.275 133.457 132.674 1.00 39.25  ? 649 VAL B CB  1 
ATOM   9205  C CG1 . VAL B 1 649 ? 129.342 134.508 132.331 1.00 39.42  ? 649 VAL B CG1 1 
ATOM   9206  C CG2 . VAL B 1 649 ? 127.803 133.795 134.096 1.00 31.13  ? 649 VAL B CG2 1 
ATOM   9207  N N   . ASN B 1 650 ? 126.585 133.174 129.284 1.00 42.21  ? 650 ASN B N   1 
ATOM   9208  C CA  . ASN B 1 650 ? 126.672 132.657 127.910 1.00 39.29  ? 650 ASN B CA  1 
ATOM   9209  C C   . ASN B 1 650 ? 126.749 133.726 126.800 1.00 41.39  ? 650 ASN B C   1 
ATOM   9210  O O   . ASN B 1 650 ? 126.558 133.410 125.631 1.00 43.19  ? 650 ASN B O   1 
ATOM   9211  C CB  . ASN B 1 650 ? 125.530 131.644 127.693 1.00 44.19  ? 650 ASN B CB  1 
ATOM   9212  C CG  . ASN B 1 650 ? 125.797 130.322 128.393 1.00 48.36  ? 650 ASN B CG  1 
ATOM   9213  O OD1 . ASN B 1 650 ? 126.857 129.733 128.259 1.00 47.24  ? 650 ASN B OD1 1 
ATOM   9214  N ND2 . ASN B 1 650 ? 124.864 129.799 129.139 1.00 44.72  ? 650 ASN B ND2 1 
ATOM   9215  N N   . HIS B 1 651 ? 127.027 134.985 127.140 1.00 43.37  ? 651 HIS B N   1 
ATOM   9216  C CA  . HIS B 1 651 ? 127.208 136.116 126.202 1.00 39.98  ? 651 HIS B CA  1 
ATOM   9217  C C   . HIS B 1 651 ? 126.009 136.440 125.300 1.00 42.66  ? 651 HIS B C   1 
ATOM   9218  O O   . HIS B 1 651 ? 126.151 137.126 124.287 1.00 50.25  ? 651 HIS B O   1 
ATOM   9219  C CB  . HIS B 1 651 ? 128.462 135.864 125.347 1.00 42.40  ? 651 HIS B CB  1 
ATOM   9220  C CG  . HIS B 1 651 ? 129.655 135.465 126.150 1.00 41.23  ? 651 HIS B CG  1 
ATOM   9221  N ND1 . HIS B 1 651 ? 130.568 136.387 126.625 1.00 44.34  ? 651 HIS B ND1 1 
ATOM   9222  C CD2 . HIS B 1 651 ? 130.083 134.255 126.570 1.00 44.88  ? 651 HIS B CD2 1 
ATOM   9223  C CE1 . HIS B 1 651 ? 131.510 135.761 127.300 1.00 43.64  ? 651 HIS B CE1 1 
ATOM   9224  N NE2 . HIS B 1 651 ? 131.236 134.451 127.281 1.00 42.42  ? 651 HIS B NE2 1 
ATOM   9225  N N   . VAL B 1 652 ? 124.813 135.979 125.664 1.00 47.14  ? 652 VAL B N   1 
ATOM   9226  C CA  . VAL B 1 652 ? 123.560 136.399 125.028 1.00 44.64  ? 652 VAL B CA  1 
ATOM   9227  C C   . VAL B 1 652 ? 123.336 137.898 125.236 1.00 46.23  ? 652 VAL B C   1 
ATOM   9228  O O   . VAL B 1 652 ? 123.762 138.463 126.246 1.00 45.90  ? 652 VAL B O   1 
ATOM   9229  C CB  . VAL B 1 652 ? 122.361 135.574 125.522 1.00 45.38  ? 652 VAL B CB  1 
ATOM   9230  C CG1 . VAL B 1 652 ? 122.545 134.090 125.172 1.00 43.86  ? 652 VAL B CG1 1 
ATOM   9231  C CG2 . VAL B 1 652 ? 122.105 135.697 127.028 1.00 47.71  ? 652 VAL B CG2 1 
ATOM   9232  N N   . ALA B 1 653 ? 122.686 138.558 124.283 1.00 51.36  ? 653 ALA B N   1 
ATOM   9233  C CA  . ALA B 1 653 ? 122.429 139.994 124.357 1.00 51.38  ? 653 ALA B CA  1 
ATOM   9234  C C   . ALA B 1 653 ? 121.601 140.367 125.603 1.00 53.52  ? 653 ALA B C   1 
ATOM   9235  O O   . ALA B 1 653 ? 120.663 139.665 125.986 1.00 52.14  ? 653 ALA B O   1 
ATOM   9236  C CB  . ALA B 1 653 ? 121.756 140.441 123.059 1.00 49.84  ? 653 ALA B CB  1 
ATOM   9237  N N   . ASP B 1 654 ? 121.948 141.485 126.236 1.00 52.55  ? 654 ASP B N   1 
ATOM   9238  C CA  . ASP B 1 654 ? 121.295 141.979 127.449 1.00 50.58  ? 654 ASP B CA  1 
ATOM   9239  C C   . ASP B 1 654 ? 119.907 142.579 127.154 1.00 51.43  ? 654 ASP B C   1 
ATOM   9240  O O   . ASP B 1 654 ? 119.752 143.774 126.912 1.00 51.33  ? 654 ASP B O   1 
ATOM   9241  C CB  . ASP B 1 654 ? 122.237 142.989 128.123 1.00 52.20  ? 654 ASP B CB  1 
ATOM   9242  C CG  . ASP B 1 654 ? 121.650 143.570 129.408 1.00 57.76  ? 654 ASP B CG  1 
ATOM   9243  O OD1 . ASP B 1 654 ? 120.720 142.961 129.989 1.00 58.12  ? 654 ASP B OD1 1 
ATOM   9244  O OD2 . ASP B 1 654 ? 122.098 144.653 129.831 1.00 57.40  ? 654 ASP B OD2 1 
ATOM   9245  N N   . ASN B 1 655 ? 118.874 141.741 127.180 1.00 45.82  ? 655 ASN B N   1 
ATOM   9246  C CA  . ASN B 1 655 ? 117.473 142.104 126.943 1.00 42.19  ? 655 ASN B CA  1 
ATOM   9247  C C   . ASN B 1 655 ? 116.781 142.787 128.143 1.00 40.98  ? 655 ASN B C   1 
ATOM   9248  O O   . ASN B 1 655 ? 115.559 142.940 128.159 1.00 44.53  ? 655 ASN B O   1 
ATOM   9249  C CB  . ASN B 1 655 ? 116.716 140.862 126.444 1.00 40.98  ? 655 ASN B CB  1 
ATOM   9250  C CG  . ASN B 1 655 ? 116.640 139.719 127.440 1.00 45.38  ? 655 ASN B CG  1 
ATOM   9251  O OD1 . ASN B 1 655 ? 117.061 139.807 128.580 1.00 50.39  ? 655 ASN B OD1 1 
ATOM   9252  N ND2 . ASN B 1 655 ? 116.128 138.584 127.032 1.00 44.54  ? 655 ASN B ND2 1 
ATOM   9253  N N   . SER B 1 656 ? 117.528 143.218 129.161 1.00 42.05  ? 656 SER B N   1 
ATOM   9254  C CA  . SER B 1 656 ? 116.958 143.796 130.379 1.00 38.78  ? 656 SER B CA  1 
ATOM   9255  C C   . SER B 1 656 ? 116.262 145.141 130.152 1.00 37.66  ? 656 SER B C   1 
ATOM   9256  O O   . SER B 1 656 ? 115.238 145.395 130.779 1.00 41.50  ? 656 SER B O   1 
ATOM   9257  C CB  . SER B 1 656 ? 118.038 143.916 131.454 1.00 37.31  ? 656 SER B CB  1 
ATOM   9258  O OG  . SER B 1 656 ? 119.095 144.714 130.986 1.00 45.08  ? 656 SER B OG  1 
ATOM   9259  N N   . TRP B 1 657 ? 116.730 145.966 129.205 1.00 28.79  ? 657 TRP B N   1 
ATOM   9260  C CA  . TRP B 1 657 ? 116.042 147.201 128.795 1.00 25.07  ? 657 TRP B CA  1 
ATOM   9261  C C   . TRP B 1 657 ? 114.643 146.929 128.228 1.00 28.34  ? 657 TRP B C   1 
ATOM   9262  O O   . TRP B 1 657 ? 113.679 147.574 128.627 1.00 34.27  ? 657 TRP B O   1 
ATOM   9263  C CB  . TRP B 1 657 ? 116.911 147.977 127.801 1.00 21.15  ? 657 TRP B CB  1 
ATOM   9264  C CG  . TRP B 1 657 ? 116.278 149.210 127.228 1.00 26.85  ? 657 TRP B CG  1 
ATOM   9265  C CD1 . TRP B 1 657 ? 116.366 150.458 127.746 1.00 27.87  ? 657 TRP B CD1 1 
ATOM   9266  C CD2 . TRP B 1 657 ? 115.462 149.346 126.031 1.00 30.03  ? 657 TRP B CD2 1 
ATOM   9267  N NE1 . TRP B 1 657 ? 115.628 151.336 126.983 1.00 29.05  ? 657 TRP B NE1 1 
ATOM   9268  C CE2 . TRP B 1 657 ? 115.041 150.703 125.910 1.00 31.31  ? 657 TRP B CE2 1 
ATOM   9269  C CE3 . TRP B 1 657 ? 115.069 148.467 124.995 1.00 24.84  ? 657 TRP B CE3 1 
ATOM   9270  C CZ2 . TRP B 1 657 ? 114.249 151.157 124.852 1.00 29.13  ? 657 TRP B CZ2 1 
ATOM   9271  C CZ3 . TRP B 1 657 ? 114.297 148.920 123.918 1.00 28.94  ? 657 TRP B CZ3 1 
ATOM   9272  C CH2 . TRP B 1 657 ? 113.864 150.255 123.848 1.00 31.67  ? 657 TRP B CH2 1 
ATOM   9273  N N   . SER B 1 658 ? 114.504 145.925 127.365 1.00 33.66  ? 658 SER B N   1 
ATOM   9274  C CA  . SER B 1 658 ? 113.225 145.515 126.789 1.00 21.31  ? 658 SER B CA  1 
ATOM   9275  C C   . SER B 1 658 ? 112.269 144.958 127.841 1.00 25.95  ? 658 SER B C   1 
ATOM   9276  O O   . SER B 1 658 ? 111.086 145.288 127.853 1.00 31.89  ? 658 SER B O   1 
ATOM   9277  C CB  . SER B 1 658 ? 113.446 144.437 125.723 1.00 27.71  ? 658 SER B CB  1 
ATOM   9278  O OG  . SER B 1 658 ? 114.422 144.858 124.792 1.00 41.52  ? 658 SER B OG  1 
ATOM   9279  N N   . ILE B 1 659 ? 112.762 144.124 128.760 1.00 29.32  ? 659 ILE B N   1 
ATOM   9280  C CA  . ILE B 1 659 ? 111.944 143.558 129.842 1.00 31.60  ? 659 ILE B CA  1 
ATOM   9281  C C   . ILE B 1 659 ? 111.485 144.651 130.819 1.00 21.00  ? 659 ILE B C   1 
ATOM   9282  O O   . ILE B 1 659 ? 110.346 144.631 131.271 1.00 23.27  ? 659 ILE B O   1 
ATOM   9283  C CB  . ILE B 1 659 ? 112.706 142.409 130.528 1.00 28.00  ? 659 ILE B CB  1 
ATOM   9284  C CG1 . ILE B 1 659 ? 112.854 141.207 129.581 1.00 26.93  ? 659 ILE B CG1 1 
ATOM   9285  C CG2 . ILE B 1 659 ? 112.020 141.967 131.832 1.00 27.78  ? 659 ILE B CG2 1 
ATOM   9286  C CD1 . ILE B 1 659 ? 113.876 140.176 130.047 1.00 27.73  ? 659 ILE B CD1 1 
ATOM   9287  N N   . TRP B 1 660 ? 112.303 145.663 131.086 1.00 17.28  ? 660 TRP B N   1 
ATOM   9288  C CA  . TRP B 1 660 ? 111.884 146.857 131.807 1.00 10.55  ? 660 TRP B CA  1 
ATOM   9289  C C   . TRP B 1 660 ? 110.856 147.711 131.044 1.00 22.08  ? 660 TRP B C   1 
ATOM   9290  O O   . TRP B 1 660 ? 109.876 148.159 131.635 1.00 29.40  ? 660 TRP B O   1 
ATOM   9291  C CB  . TRP B 1 660 ? 113.126 147.652 132.186 1.00 17.93  ? 660 TRP B CB  1 
ATOM   9292  C CG  . TRP B 1 660 ? 112.845 149.017 132.709 1.00 26.63  ? 660 TRP B CG  1 
ATOM   9293  C CD1 . TRP B 1 660 ? 112.223 149.307 133.870 1.00 15.35  ? 660 TRP B CD1 1 
ATOM   9294  C CD2 . TRP B 1 660 ? 113.066 150.287 132.039 1.00 23.18  ? 660 TRP B CD2 1 
ATOM   9295  N NE1 . TRP B 1 660 ? 112.112 150.674 133.995 1.00 16.84  ? 660 TRP B NE1 1 
ATOM   9296  C CE2 . TRP B 1 660 ? 112.637 151.326 132.906 1.00 21.55  ? 660 TRP B CE2 1 
ATOM   9297  C CE3 . TRP B 1 660 ? 113.593 150.660 130.786 1.00 25.93  ? 660 TRP B CE3 1 
ATOM   9298  C CZ2 . TRP B 1 660 ? 112.781 152.679 132.573 1.00 19.79  ? 660 TRP B CZ2 1 
ATOM   9299  C CZ3 . TRP B 1 660 ? 113.710 152.010 130.428 1.00 28.74  ? 660 TRP B CZ3 1 
ATOM   9300  C CH2 . TRP B 1 660 ? 113.311 153.018 131.320 1.00 28.98  ? 660 TRP B CH2 1 
ATOM   9301  N N   . LYS B 1 661 ? 110.983 147.889 129.723 1.00 26.49  ? 661 LYS B N   1 
ATOM   9302  C CA  . LYS B 1 661 ? 109.940 148.541 128.910 1.00 12.24  ? 661 LYS B CA  1 
ATOM   9303  C C   . LYS B 1 661 ? 108.614 147.780 128.959 1.00 13.22  ? 661 LYS B C   1 
ATOM   9304  O O   . LYS B 1 661 ? 107.564 148.412 128.991 1.00 23.78  ? 661 LYS B O   1 
ATOM   9305  C CB  . LYS B 1 661 ? 110.404 148.721 127.456 1.00 18.81  ? 661 LYS B CB  1 
ATOM   9306  C CG  . LYS B 1 661 ? 111.466 149.800 127.232 1.00 13.68  ? 661 LYS B CG  1 
ATOM   9307  C CD  . LYS B 1 661 ? 111.040 151.199 127.688 1.00 16.52  ? 661 LYS B CD  1 
ATOM   9308  C CE  . LYS B 1 661 ? 112.002 152.230 127.097 1.00 27.22  ? 661 LYS B CE  1 
ATOM   9309  N NZ  . LYS B 1 661 ? 111.760 153.602 127.611 1.00 30.44  ? 661 LYS B NZ  1 
ATOM   9310  N N   . LEU B 1 662 ? 108.629 146.453 129.056 1.00 16.36  ? 662 LEU B N   1 
ATOM   9311  C CA  . LEU B 1 662 ? 107.435 145.647 129.313 1.00 12.57  ? 662 LEU B CA  1 
ATOM   9312  C C   . LEU B 1 662 ? 106.866 145.842 130.730 1.00 15.77  ? 662 LEU B C   1 
ATOM   9313  O O   . LEU B 1 662 ? 105.656 145.951 130.879 1.00 28.76  ? 662 LEU B O   1 
ATOM   9314  C CB  . LEU B 1 662 ? 107.748 144.181 128.984 1.00 16.98  ? 662 LEU B CB  1 
ATOM   9315  C CG  . LEU B 1 662 ? 106.593 143.195 129.219 1.00 20.55  ? 662 LEU B CG  1 
ATOM   9316  C CD1 . LEU B 1 662 ? 105.407 143.433 128.296 1.00 16.72  ? 662 LEU B CD1 1 
ATOM   9317  C CD2 . LEU B 1 662 ? 107.097 141.788 128.983 1.00 14.86  ? 662 LEU B CD2 1 
ATOM   9318  N N   . GLN B 1 663 ? 107.691 145.968 131.768 1.00 25.38  ? 663 GLN B N   1 
ATOM   9319  C CA  . GLN B 1 663 ? 107.221 146.322 133.115 1.00 9.62   ? 663 GLN B CA  1 
ATOM   9320  C C   . GLN B 1 663 ? 106.536 147.687 133.155 1.00 15.61  ? 663 GLN B C   1 
ATOM   9321  O O   . GLN B 1 663 ? 105.461 147.818 133.742 1.00 25.43  ? 663 GLN B O   1 
ATOM   9322  C CB  . GLN B 1 663 ? 108.381 146.331 134.109 1.00 15.15  ? 663 GLN B CB  1 
ATOM   9323  C CG  . GLN B 1 663 ? 108.925 144.942 134.419 1.00 12.53  ? 663 GLN B CG  1 
ATOM   9324  C CD  . GLN B 1 663 ? 110.114 145.009 135.360 1.00 16.31  ? 663 GLN B CD  1 
ATOM   9325  O OE1 . GLN B 1 663 ? 110.636 146.065 135.668 1.00 30.67  ? 663 GLN B OE1 1 
ATOM   9326  N NE2 . GLN B 1 663 ? 110.563 143.887 135.857 1.00 24.77  ? 663 GLN B NE2 1 
ATOM   9327  N N   . LYS B 1 664 ? 107.123 148.692 132.495 1.00 24.83  ? 664 LYS B N   1 
ATOM   9328  C CA  . LYS B 1 664 ? 106.499 150.003 132.289 1.00 4.45   ? 664 LYS B CA  1 
ATOM   9329  C C   . LYS B 1 664 ? 105.189 149.909 131.519 1.00 17.62  ? 664 LYS B C   1 
ATOM   9330  O O   . LYS B 1 664 ? 104.231 150.537 131.935 1.00 34.20  ? 664 LYS B O   1 
ATOM   9331  C CB  . LYS B 1 664 ? 107.466 150.963 131.596 1.00 15.21  ? 664 LYS B CB  1 
ATOM   9332  C CG  . LYS B 1 664 ? 108.484 151.544 132.575 1.00 15.92  ? 664 LYS B CG  1 
ATOM   9333  C CD  . LYS B 1 664 ? 109.192 152.755 131.965 1.00 17.77  ? 664 LYS B CD  1 
ATOM   9334  C CE  . LYS B 1 664 ? 109.730 153.617 133.111 1.00 33.85  ? 664 LYS B CE  1 
ATOM   9335  N NZ  . LYS B 1 664 ? 110.262 154.921 132.625 1.00 37.07  ? 664 LYS B NZ  1 
ATOM   9336  N N   . ALA B 1 665 ? 105.107 149.092 130.471 1.00 20.17  ? 665 ALA B N   1 
ATOM   9337  C CA  . ALA B 1 665 ? 103.881 148.862 129.715 1.00 7.71   ? 665 ALA B CA  1 
ATOM   9338  C C   . ALA B 1 665 ? 102.760 148.277 130.579 1.00 16.96  ? 665 ALA B C   1 
ATOM   9339  O O   . ALA B 1 665 ? 101.657 148.807 130.581 1.00 26.32  ? 665 ALA B O   1 
ATOM   9340  C CB  . ALA B 1 665 ? 104.193 147.971 128.510 1.00 10.43  ? 665 ALA B CB  1 
ATOM   9341  N N   . ILE B 1 666 ? 103.033 147.237 131.365 1.00 18.55  ? 666 ILE B N   1 
ATOM   9342  C CA  . ILE B 1 666 ? 102.071 146.629 132.296 1.00 20.00  ? 666 ILE B CA  1 
ATOM   9343  C C   . ILE B 1 666 ? 101.599 147.642 133.347 1.00 18.44  ? 666 ILE B C   1 
ATOM   9344  O O   . ILE B 1 666 ? 100.406 147.769 133.599 1.00 27.29  ? 666 ILE B O   1 
ATOM   9345  C CB  . ILE B 1 666 ? 102.711 145.372 132.932 1.00 18.56  ? 666 ILE B CB  1 
ATOM   9346  C CG1 . ILE B 1 666 ? 102.840 144.257 131.877 1.00 20.01  ? 666 ILE B CG1 1 
ATOM   9347  C CG2 . ILE B 1 666 ? 101.919 144.857 134.140 1.00 22.12  ? 666 ILE B CG2 1 
ATOM   9348  C CD1 . ILE B 1 666 ? 103.902 143.214 132.219 1.00 27.66  ? 666 ILE B CD1 1 
ATOM   9349  N N   . SER B 1 667 ? 102.551 148.362 133.947 1.00 25.73  ? 667 SER B N   1 
ATOM   9350  C CA  . SER B 1 667 ? 102.198 149.393 134.958 1.00 19.55  ? 667 SER B CA  1 
ATOM   9351  C C   . SER B 1 667 ? 101.261 150.428 134.330 1.00 18.07  ? 667 SER B C   1 
ATOM   9352  O O   . SER B 1 667 ? 100.211 150.720 134.935 1.00 31.07  ? 667 SER B O   1 
ATOM   9353  C CB  . SER B 1 667 ? 103.436 150.044 135.518 1.00 19.35  ? 667 SER B CB  1 
ATOM   9354  O OG  . SER B 1 667 ? 103.093 151.098 136.405 1.00 40.37  ? 667 SER B OG  1 
ATOM   9355  N N   . VAL B 1 668 ? 101.632 150.956 133.160 1.00 19.77  ? 668 VAL B N   1 
ATOM   9356  C CA  . VAL B 1 668 ? 100.804 151.998 132.479 1.00 20.02  ? 668 VAL B CA  1 
ATOM   9357  C C   . VAL B 1 668 ? 99.414  151.425 132.188 1.00 21.86  ? 668 VAL B C   1 
ATOM   9358  O O   . VAL B 1 668 ? 98.423  152.037 132.635 1.00 32.11  ? 668 VAL B O   1 
ATOM   9359  C CB  . VAL B 1 668 ? 101.483 152.497 131.189 1.00 22.81  ? 668 VAL B CB  1 
ATOM   9360  C CG1 . VAL B 1 668 ? 100.511 153.248 130.292 1.00 28.11  ? 668 VAL B CG1 1 
ATOM   9361  C CG2 . VAL B 1 668 ? 102.709 153.347 131.486 1.00 19.96  ? 668 VAL B CG2 1 
ATOM   9362  N N   . LEU B 1 669 ? 99.343  150.300 131.470 1.00 26.68  ? 669 LEU B N   1 
ATOM   9363  C CA  . LEU B 1 669 ? 98.051  149.743 131.093 1.00 21.37  ? 669 LEU B CA  1 
ATOM   9364  C C   . LEU B 1 669 ? 97.152  149.493 132.307 1.00 27.76  ? 669 LEU B C   1 
ATOM   9365  O O   . LEU B 1 669 ? 95.935  149.528 132.173 1.00 34.29  ? 669 LEU B O   1 
ATOM   9366  C CB  . LEU B 1 669 ? 98.287  148.472 130.269 1.00 24.50  ? 669 LEU B CB  1 
ATOM   9367  C CG  . LEU B 1 669 ? 98.936  148.764 128.904 1.00 25.97  ? 669 LEU B CG  1 
ATOM   9368  C CD1 . LEU B 1 669 ? 99.534  147.494 128.320 1.00 24.15  ? 669 LEU B CD1 1 
ATOM   9369  C CD2 . LEU B 1 669 ? 97.931  149.314 127.903 1.00 26.69  ? 669 LEU B CD2 1 
ATOM   9370  N N   . GLU B 1 670 ? 97.718  149.303 133.500 1.00 35.20  ? 670 GLU B N   1 
ATOM   9371  C CA  . GLU B 1 670 ? 96.973  149.311 134.755 1.00 22.19  ? 670 GLU B CA  1 
ATOM   9372  C C   . GLU B 1 670 ? 96.573  150.717 135.213 1.00 31.54  ? 670 GLU B C   1 
ATOM   9373  O O   . GLU B 1 670 ? 95.392  150.955 135.459 1.00 37.59  ? 670 GLU B O   1 
ATOM   9374  C CB  . GLU B 1 670 ? 97.779  148.581 135.837 1.00 30.07  ? 670 GLU B CB  1 
ATOM   9375  C CG  . GLU B 1 670 ? 97.586  147.066 135.734 1.00 36.49  ? 670 GLU B CG  1 
ATOM   9376  C CD  . GLU B 1 670 ? 96.116  146.683 135.939 1.00 43.32  ? 670 GLU B CD  1 
ATOM   9377  O OE1 . GLU B 1 670 ? 95.498  147.150 136.918 1.00 43.48  ? 670 GLU B OE1 1 
ATOM   9378  O OE2 . GLU B 1 670 ? 95.537  145.950 135.106 1.00 44.29  ? 670 GLU B OE2 1 
ATOM   9379  N N   . MET B 1 671 ? 97.516  151.662 135.273 1.00 30.15  ? 671 MET B N   1 
ATOM   9380  C CA  . MET B 1 671 ? 97.255  153.050 135.662 1.00 23.28  ? 671 MET B CA  1 
ATOM   9381  C C   . MET B 1 671 ? 96.239  153.771 134.773 1.00 32.08  ? 671 MET B C   1 
ATOM   9382  O O   . MET B 1 671 ? 95.483  154.597 135.273 1.00 35.75  ? 671 MET B O   1 
ATOM   9383  C CB  . MET B 1 671 ? 98.554  153.851 135.659 1.00 26.41  ? 671 MET B CB  1 
ATOM   9384  C CG  . MET B 1 671 ? 99.457  153.527 136.841 1.00 27.40  ? 671 MET B CG  1 
ATOM   9385  S SD  . MET B 1 671 ? 100.826 154.687 136.988 1.00 31.61  ? 671 MET B SD  1 
ATOM   9386  C CE  . MET B 1 671 ? 101.836 154.241 135.559 1.00 24.18  ? 671 MET B CE  1 
ATOM   9387  N N   . GLU B 1 672 ? 96.171  153.457 133.478 1.00 34.85  ? 672 GLU B N   1 
ATOM   9388  C CA  . GLU B 1 672 ? 95.179  154.021 132.561 1.00 27.38  ? 672 GLU B CA  1 
ATOM   9389  C C   . GLU B 1 672 ? 93.723  153.734 132.966 1.00 34.76  ? 672 GLU B C   1 
ATOM   9390  O O   . GLU B 1 672 ? 92.851  154.527 132.616 1.00 36.70  ? 672 GLU B O   1 
ATOM   9391  C CB  . GLU B 1 672 ? 95.414  153.502 131.137 1.00 34.24  ? 672 GLU B CB  1 
ATOM   9392  C CG  . GLU B 1 672 ? 96.501  154.283 130.399 1.00 32.34  ? 672 GLU B CG  1 
ATOM   9393  C CD  . GLU B 1 672 ? 96.582  153.874 128.924 1.00 40.21  ? 672 GLU B CD  1 
ATOM   9394  O OE1 . GLU B 1 672 ? 96.686  152.670 128.618 1.00 37.22  ? 672 GLU B OE1 1 
ATOM   9395  O OE2 . GLU B 1 672 ? 96.495  154.757 128.043 1.00 49.10  ? 672 GLU B OE2 1 
ATOM   9396  N N   . ASN B 1 673 ? 93.445  152.662 133.717 1.00 40.12  ? 673 ASN B N   1 
ATOM   9397  C CA  . ASN B 1 673 ? 92.109  152.375 134.266 1.00 39.97  ? 673 ASN B CA  1 
ATOM   9398  C C   . ASN B 1 673 ? 91.753  153.228 135.498 1.00 41.63  ? 673 ASN B C   1 
ATOM   9399  O O   . ASN B 1 673 ? 90.600  153.244 135.925 1.00 46.28  ? 673 ASN B O   1 
ATOM   9400  C CB  . ASN B 1 673 ? 92.009  150.887 134.640 1.00 37.24  ? 673 ASN B CB  1 
ATOM   9401  C CG  . ASN B 1 673 ? 92.316  149.954 133.490 1.00 40.21  ? 673 ASN B CG  1 
ATOM   9402  O OD1 . ASN B 1 673 ? 91.799  150.082 132.391 1.00 43.54  ? 673 ASN B OD1 1 
ATOM   9403  N ND2 . ASN B 1 673 ? 93.170  148.990 133.699 1.00 42.89  ? 673 ASN B ND2 1 
ATOM   9404  N N   . GLY B 1 674 ? 92.727  153.916 136.100 1.00 37.14  ? 674 GLY B N   1 
ATOM   9405  C CA  . GLY B 1 674 ? 92.588  154.573 137.393 1.00 36.85  ? 674 GLY B CA  1 
ATOM   9406  C C   . GLY B 1 674 ? 92.480  153.586 138.553 1.00 32.26  ? 674 GLY B C   1 
ATOM   9407  O O   . GLY B 1 674 ? 92.940  152.450 138.477 1.00 38.21  ? 674 GLY B O   1 
ATOM   9408  N N   . TYR B 1 675 ? 91.894  154.032 139.653 1.00 37.80  ? 675 TYR B N   1 
ATOM   9409  C CA  . TYR B 1 675 ? 91.756  153.251 140.884 1.00 39.83  ? 675 TYR B CA  1 
ATOM   9410  C C   . TYR B 1 675 ? 90.439  152.469 140.958 1.00 37.77  ? 675 TYR B C   1 
ATOM   9411  O O   . TYR B 1 675 ? 89.459  152.845 140.311 1.00 48.94  ? 675 TYR B O   1 
ATOM   9412  C CB  . TYR B 1 675 ? 91.907  154.195 142.076 1.00 33.74  ? 675 TYR B CB  1 
ATOM   9413  C CG  . TYR B 1 675 ? 93.167  155.032 142.045 1.00 34.83  ? 675 TYR B CG  1 
ATOM   9414  C CD1 . TYR B 1 675 ? 94.422  154.403 142.145 1.00 33.98  ? 675 TYR B CD1 1 
ATOM   9415  C CD2 . TYR B 1 675 ? 93.093  156.427 141.915 1.00 39.07  ? 675 TYR B CD2 1 
ATOM   9416  C CE1 . TYR B 1 675 ? 95.599  155.165 142.106 1.00 32.58  ? 675 TYR B CE1 1 
ATOM   9417  C CE2 . TYR B 1 675 ? 94.272  157.195 141.893 1.00 38.54  ? 675 TYR B CE2 1 
ATOM   9418  C CZ  . TYR B 1 675 ? 95.525  156.566 141.985 1.00 34.97  ? 675 TYR B CZ  1 
ATOM   9419  O OH  . TYR B 1 675 ? 96.655  157.316 141.960 1.00 34.66  ? 675 TYR B OH  1 
ATOM   9420  N N   . TRP B 1 676 ? 90.374  151.440 141.804 1.00 33.06  ? 676 TRP B N   1 
ATOM   9421  C CA  . TRP B 1 676 ? 89.191  150.579 141.958 1.00 32.98  ? 676 TRP B CA  1 
ATOM   9422  C C   . TRP B 1 676 ? 87.917  151.360 142.317 1.00 36.33  ? 676 TRP B C   1 
ATOM   9423  O O   . TRP B 1 676 ? 86.827  151.003 141.875 1.00 45.04  ? 676 TRP B O   1 
ATOM   9424  C CB  . TRP B 1 676 ? 89.487  149.486 143.000 1.00 34.51  ? 676 TRP B CB  1 
ATOM   9425  C CG  . TRP B 1 676 ? 89.718  149.922 144.417 1.00 34.40  ? 676 TRP B CG  1 
ATOM   9426  C CD1 . TRP B 1 676 ? 90.919  150.194 144.970 1.00 35.81  ? 676 TRP B CD1 1 
ATOM   9427  C CD2 . TRP B 1 676 ? 88.738  150.175 145.471 1.00 37.28  ? 676 TRP B CD2 1 
ATOM   9428  N NE1 . TRP B 1 676 ? 90.755  150.588 146.280 1.00 33.64  ? 676 TRP B NE1 1 
ATOM   9429  C CE2 . TRP B 1 676 ? 89.428  150.632 146.631 1.00 35.62  ? 676 TRP B CE2 1 
ATOM   9430  C CE3 . TRP B 1 676 ? 87.332  150.093 145.559 1.00 38.08  ? 676 TRP B CE3 1 
ATOM   9431  C CZ2 . TRP B 1 676 ? 88.762  151.017 147.799 1.00 40.63  ? 676 TRP B CZ2 1 
ATOM   9432  C CZ3 . TRP B 1 676 ? 86.653  150.481 146.728 1.00 36.13  ? 676 TRP B CZ3 1 
ATOM   9433  C CH2 . TRP B 1 676 ? 87.362  150.953 147.841 1.00 40.41  ? 676 TRP B CH2 1 
ATOM   9434  N N   . TRP B 1 677 ? 88.057  152.450 143.065 1.00 36.99  ? 677 TRP B N   1 
ATOM   9435  C CA  . TRP B 1 677 ? 86.993  153.351 143.505 1.00 36.20  ? 677 TRP B CA  1 
ATOM   9436  C C   . TRP B 1 677 ? 86.732  154.532 142.555 1.00 41.49  ? 677 TRP B C   1 
ATOM   9437  O O   . TRP B 1 677 ? 85.719  155.212 142.708 1.00 45.96  ? 677 TRP B O   1 
ATOM   9438  C CB  . TRP B 1 677 ? 87.395  153.869 144.892 1.00 38.41  ? 677 TRP B CB  1 
ATOM   9439  C CG  . TRP B 1 677 ? 88.682  154.629 144.921 1.00 36.04  ? 677 TRP B CG  1 
ATOM   9440  C CD1 . TRP B 1 677 ? 89.903  154.085 145.108 1.00 29.48  ? 677 TRP B CD1 1 
ATOM   9441  C CD2 . TRP B 1 677 ? 88.915  156.055 144.715 1.00 37.91  ? 677 TRP B CD2 1 
ATOM   9442  N NE1 . TRP B 1 677 ? 90.865  155.063 145.014 1.00 29.14  ? 677 TRP B NE1 1 
ATOM   9443  C CE2 . TRP B 1 677 ? 90.319  156.291 144.735 1.00 35.67  ? 677 TRP B CE2 1 
ATOM   9444  C CE3 . TRP B 1 677 ? 88.082  157.174 144.502 1.00 37.55  ? 677 TRP B CE3 1 
ATOM   9445  C CZ2 . TRP B 1 677 ? 90.873  157.560 144.529 1.00 37.12  ? 677 TRP B CZ2 1 
ATOM   9446  C CZ3 . TRP B 1 677 ? 88.628  158.456 144.314 1.00 40.16  ? 677 TRP B CZ3 1 
ATOM   9447  C CH2 . TRP B 1 677 ? 90.020  158.651 144.322 1.00 39.88  ? 677 TRP B CH2 1 
ATOM   9448  N N   . CYS B 1 678 ? 87.627  154.816 141.600 1.00 46.18  ? 678 CYS B N   1 
ATOM   9449  C CA  . CYS B 1 678 ? 87.603  156.042 140.792 1.00 45.03  ? 678 CYS B CA  1 
ATOM   9450  C C   . CYS B 1 678 ? 87.286  155.798 139.306 1.00 50.06  ? 678 CYS B C   1 
ATOM   9451  O O   . CYS B 1 678 ? 86.549  156.577 138.703 1.00 54.39  ? 678 CYS B O   1 
ATOM   9452  C CB  . CYS B 1 678 ? 88.934  156.778 140.984 1.00 48.15  ? 678 CYS B CB  1 
ATOM   9453  S SG  . CYS B 1 678 ? 88.810  158.471 140.344 1.00 62.86  ? 678 CYS B SG  1 
ATOM   9454  N N   . ARG B 1 679 ? 87.704  154.612 138.799 1.00 53.64  ? 679 ARG B N   1 
ATOM   9455  C CA  . ARG B 1 679 ? 87.287  154.126 137.447 1.00 55.54  ? 679 ARG B CA  1 
ATOM   9456  C C   . ARG B 1 679 ? 87.277  155.301 136.460 1.00 52.92  ? 679 ARG B C   1 
ATOM   9457  O O   . ARG B 1 679 ? 86.171  155.760 136.115 1.00 54.57  ? 679 ARG B O   1 
ATOM   9458  C CB  . ARG B 1 679 ? 85.904  153.493 137.730 1.00 57.64  ? 679 ARG B CB  1 
ATOM   9459  C CG  . ARG B 1 679 ? 85.621  152.217 136.931 1.00 56.69  ? 679 ARG B CG  1 
ATOM   9460  C CD  . ARG B 1 679 ? 86.425  151.012 137.434 1.00 55.39  ? 679 ARG B CD  1 
ATOM   9461  N NE  . ARG B 1 679 ? 86.176  150.676 138.829 1.00 55.28  ? 679 ARG B NE  1 
ATOM   9462  C CZ  . ARG B 1 679 ? 85.316  149.751 139.236 1.00 59.48  ? 679 ARG B CZ  1 
ATOM   9463  N NH1 . ARG B 1 679 ? 85.159  149.513 140.527 1.00 58.47  ? 679 ARG B NH1 1 
ATOM   9464  N NH2 . ARG B 1 679 ? 84.617  149.062 138.352 1.00 56.61  ? 679 ARG B NH2 1 
ATOM   9465  N N   . ARG B 1 680 ? 88.451  155.762 136.016 1.00 53.43  ? 680 ARG B N   1 
ATOM   9466  C CA  . ARG B 1 680 ? 88.603  156.920 135.108 1.00 53.71  ? 680 ARG B CA  1 
ATOM   9467  C C   . ARG B 1 680 ? 88.280  156.647 133.627 1.00 54.05  ? 680 ARG B C   1 
ATOM   9468  O O   . ARG B 1 680 ? 88.514  155.556 133.111 1.00 53.98  ? 680 ARG B O   1 
ATOM   9469  C CB  . ARG B 1 680 ? 89.991  157.572 135.276 1.00 52.08  ? 680 ARG B CB  1 
ATOM   9470  C CG  . ARG B 1 680 ? 91.103  156.944 134.428 1.00 48.15  ? 680 ARG B CG  1 
ATOM   9471  C CD  . ARG B 1 680 ? 92.446  157.638 134.641 1.00 48.73  ? 680 ARG B CD  1 
ATOM   9472  N NE  . ARG B 1 680 ? 93.349  157.382 133.508 1.00 57.88  ? 680 ARG B NE  1 
ATOM   9473  C CZ  . ARG B 1 680 ? 94.363  158.134 133.118 1.00 54.36  ? 680 ARG B CZ  1 
ATOM   9474  N NH1 . ARG B 1 680 ? 94.955  157.910 131.985 1.00 49.68  ? 680 ARG B NH1 1 
ATOM   9475  N NH2 . ARG B 1 680 ? 94.799  159.129 133.828 1.00 50.11  ? 680 ARG B NH2 1 
ATOM   9476  N N   . LYS B 1 681 ? 87.811  157.683 132.924 1.00 60.46  ? 681 LYS B N   1 
ATOM   9477  C CA  . LYS B 1 681 ? 87.599  157.708 131.463 1.00 62.30  ? 681 LYS B CA  1 
ATOM   9478  C C   . LYS B 1 681 ? 88.933  157.838 130.709 1.00 61.38  ? 681 LYS B C   1 
ATOM   9479  O O   . LYS B 1 681 ? 89.794  158.621 131.105 1.00 56.75  ? 681 LYS B O   1 
ATOM   9480  C CB  . LYS B 1 681 ? 86.644  158.871 131.129 1.00 62.13  ? 681 LYS B CB  1 
ATOM   9481  C CG  . LYS B 1 681 ? 86.085  158.886 129.697 1.00 63.11  ? 681 LYS B CG  1 
ATOM   9482  C CD  . LYS B 1 681 ? 85.102  157.737 129.429 1.00 64.18  ? 681 LYS B CD  1 
ATOM   9483  C CE  . LYS B 1 681 ? 84.460  157.913 128.050 1.00 64.25  ? 681 LYS B CE  1 
ATOM   9484  N NZ  . LYS B 1 681 ? 83.444  156.871 127.777 1.00 63.38  ? 681 LYS B NZ  1 
ATOM   9485  N N   . LYS B 1 682 ? 89.103  157.080 129.621 1.00 55.28  ? 682 LYS B N   1 
ATOM   9486  C CA  . LYS B 1 682 ? 90.302  157.084 128.760 1.00 56.31  ? 682 LYS B CA  1 
ATOM   9487  C C   . LYS B 1 682 ? 90.190  158.088 127.608 1.00 56.33  ? 682 LYS B C   1 
ATOM   9488  O O   . LYS B 1 682 ? 89.091  158.472 127.215 1.00 58.56  ? 682 LYS B O   1 
ATOM   9489  C CB  . LYS B 1 682 ? 90.560  155.659 128.236 1.00 53.05  ? 682 LYS B CB  1 
ATOM   9490  C CG  . LYS B 1 682 ? 90.809  154.679 129.388 1.00 51.98  ? 682 LYS B CG  1 
ATOM   9491  C CD  . LYS B 1 682 ? 91.171  153.284 128.890 1.00 52.69  ? 682 LYS B CD  1 
ATOM   9492  C CE  . LYS B 1 682 ? 91.344  152.363 130.095 1.00 53.91  ? 682 LYS B CE  1 
ATOM   9493  N NZ  . LYS B 1 682 ? 91.572  150.959 129.699 1.00 55.29  ? 682 LYS B NZ  1 
ATOM   9494  N N   . HIS B 1 683 ? 91.319  158.471 127.013 1.00 49.53  ? 683 HIS B N   1 
ATOM   9495  C CA  . HIS B 1 683 ? 91.381  159.314 125.812 1.00 51.95  ? 683 HIS B CA  1 
ATOM   9496  C C   . HIS B 1 683 ? 92.101  158.594 124.661 1.00 53.17  ? 683 HIS B C   1 
ATOM   9497  O O   . HIS B 1 683 ? 93.003  157.784 124.948 1.00 53.04  ? 683 HIS B O   1 
ATOM   9498  C CB  . HIS B 1 683 ? 92.090  160.636 126.132 1.00 55.29  ? 683 HIS B CB  1 
ATOM   9499  C CG  . HIS B 1 683 ? 93.576  160.511 126.202 1.00 55.70  ? 683 HIS B CG  1 
ATOM   9500  N ND1 . HIS B 1 683 ? 94.234  160.173 127.368 1.00 55.07  ? 683 HIS B ND1 1 
ATOM   9501  C CD2 . HIS B 1 683 ? 94.530  160.668 125.259 1.00 52.58  ? 683 HIS B CD2 1 
ATOM   9502  C CE1 . HIS B 1 683 ? 95.532  160.132 127.141 1.00 55.80  ? 683 HIS B CE1 1 
ATOM   9503  N NE2 . HIS B 1 683 ? 95.739  160.433 125.854 1.00 53.51  ? 683 HIS B NE2 1 
ATOM   9504  N N   . ARG B 1 684 ? 91.712  158.882 123.413 1.00 45.86  ? 684 ARG B N   1 
ATOM   9505  C CA  . ARG B 1 684 ? 92.396  158.360 122.222 1.00 38.72  ? 684 ARG B CA  1 
ATOM   9506  C C   . ARG B 1 684 ? 93.753  159.021 122.028 1.00 42.71  ? 684 ARG B C   1 
ATOM   9507  O O   . ARG B 1 684 ? 93.890  160.226 122.234 1.00 42.33  ? 684 ARG B O   1 
ATOM   9508  C CB  . ARG B 1 684 ? 91.563  158.571 120.953 1.00 41.19  ? 684 ARG B CB  1 
ATOM   9509  C CG  . ARG B 1 684 ? 90.245  157.811 121.016 1.00 42.45  ? 684 ARG B CG  1 
ATOM   9510  C CD  . ARG B 1 684 ? 89.575  157.668 119.655 1.00 39.06  ? 684 ARG B CD  1 
ATOM   9511  N NE  . ARG B 1 684 ? 90.248  156.642 118.842 1.00 35.80  ? 684 ARG B NE  1 
ATOM   9512  C CZ  . ARG B 1 684 ? 89.677  155.802 118.004 1.00 42.11  ? 684 ARG B CZ  1 
ATOM   9513  N NH1 . ARG B 1 684 ? 90.374  154.855 117.453 1.00 44.63  ? 684 ARG B NH1 1 
ATOM   9514  N NH2 . ARG B 1 684 ? 88.415  155.867 117.704 1.00 42.48  ? 684 ARG B NH2 1 
ATOM   9515  N N   . GLU B 1 685 ? 94.718  158.261 121.535 1.00 42.30  ? 685 GLU B N   1 
ATOM   9516  C CA  . GLU B 1 685 ? 96.012  158.785 121.112 1.00 38.72  ? 685 GLU B CA  1 
ATOM   9517  C C   . GLU B 1 685 ? 96.209  158.759 119.596 1.00 45.53  ? 685 GLU B C   1 
ATOM   9518  O O   . GLU B 1 685 ? 95.433  158.167 118.846 1.00 50.64  ? 685 GLU B O   1 
ATOM   9519  C CB  . GLU B 1 685 ? 97.131  158.104 121.900 1.00 39.49  ? 685 GLU B CB  1 
ATOM   9520  C CG  . GLU B 1 685 ? 97.034  158.627 123.338 1.00 46.41  ? 685 GLU B CG  1 
ATOM   9521  C CD  . GLU B 1 685 ? 98.039  157.966 124.262 1.00 45.56  ? 685 GLU B CD  1 
ATOM   9522  O OE1 . GLU B 1 685 ? 99.247  158.024 123.956 1.00 44.43  ? 685 GLU B OE1 1 
ATOM   9523  O OE2 . GLU B 1 685 ? 97.599  157.421 125.298 1.00 51.88  ? 685 GLU B OE2 1 
ATOM   9524  N N   . GLY B 1 686 ? 97.217  159.495 119.130 1.00 39.36  ? 686 GLY B N   1 
ATOM   9525  C CA  . GLY B 1 686 ? 97.271  159.945 117.746 1.00 37.17  ? 686 GLY B CA  1 
ATOM   9526  C C   . GLY B 1 686 ? 96.198  160.988 117.432 1.00 37.92  ? 686 GLY B C   1 
ATOM   9527  O O   . GLY B 1 686 ? 95.594  161.581 118.328 1.00 42.37  ? 686 GLY B O   1 
ATOM   9528  N N   . ARG B 1 687 ? 95.969  161.234 116.148 1.00 45.69  ? 687 ARG B N   1 
ATOM   9529  C CA  . ARG B 1 687 ? 94.970  162.167 115.615 1.00 45.41  ? 687 ARG B CA  1 
ATOM   9530  C C   . ARG B 1 687 ? 94.172  161.490 114.519 1.00 44.80  ? 687 ARG B C   1 
ATOM   9531  O O   . ARG B 1 687 ? 94.721  160.685 113.772 1.00 49.27  ? 687 ARG B O   1 
ATOM   9532  C CB  . ARG B 1 687 ? 95.648  163.425 115.058 1.00 47.02  ? 687 ARG B CB  1 
ATOM   9533  C CG  . ARG B 1 687 ? 96.271  164.307 116.144 1.00 48.17  ? 687 ARG B CG  1 
ATOM   9534  C CD  . ARG B 1 687 ? 96.883  165.583 115.556 1.00 52.84  ? 687 ARG B CD  1 
ATOM   9535  N NE  . ARG B 1 687 ? 95.865  166.451 114.931 1.00 56.40  ? 687 ARG B NE  1 
ATOM   9536  C CZ  . ARG B 1 687 ? 96.055  167.639 114.394 1.00 54.61  ? 687 ARG B CZ  1 
ATOM   9537  N NH1 . ARG B 1 687 ? 95.073  168.265 113.819 1.00 54.95  ? 687 ARG B NH1 1 
ATOM   9538  N NH2 . ARG B 1 687 ? 97.213  168.233 114.412 1.00 52.05  ? 687 ARG B NH2 1 
ATOM   9539  N N   . LEU B 1 688 ? 92.899  161.837 114.377 1.00 41.32  ? 688 LEU B N   1 
ATOM   9540  C CA  . LEU B 1 688 ? 92.117  161.466 113.199 1.00 41.24  ? 688 LEU B CA  1 
ATOM   9541  C C   . LEU B 1 688 ? 92.629  162.240 111.975 1.00 42.89  ? 688 LEU B C   1 
ATOM   9542  O O   . LEU B 1 688 ? 92.485  163.458 111.908 1.00 49.03  ? 688 LEU B O   1 
ATOM   9543  C CB  . LEU B 1 688 ? 90.633  161.727 113.489 1.00 45.49  ? 688 LEU B CB  1 
ATOM   9544  C CG  . LEU B 1 688 ? 89.682  161.345 112.349 1.00 42.36  ? 688 LEU B CG  1 
ATOM   9545  C CD1 . LEU B 1 688 ? 89.812  159.873 111.964 1.00 43.14  ? 688 LEU B CD1 1 
ATOM   9546  C CD2 . LEU B 1 688 ? 88.247  161.593 112.798 1.00 46.61  ? 688 LEU B CD2 1 
ATOM   9547  N N   . LEU B 1 689 ? 93.249  161.543 111.023 1.00 44.88  ? 689 LEU B N   1 
ATOM   9548  C CA  . LEU B 1 689 ? 93.892  162.113 109.835 1.00 47.47  ? 689 LEU B CA  1 
ATOM   9549  C C   . LEU B 1 689 ? 93.464  161.365 108.571 1.00 50.99  ? 689 LEU B C   1 
ATOM   9550  O O   . LEU B 1 689 ? 93.314  160.143 108.587 1.00 53.69  ? 689 LEU B O   1 
ATOM   9551  C CB  . LEU B 1 689 ? 95.427  162.063 109.979 1.00 46.69  ? 689 LEU B CB  1 
ATOM   9552  C CG  . LEU B 1 689 ? 96.010  162.885 111.139 1.00 52.28  ? 689 LEU B CG  1 
ATOM   9553  C CD1 . LEU B 1 689 ? 97.502  162.607 111.261 1.00 50.58  ? 689 LEU B CD1 1 
ATOM   9554  C CD2 . LEU B 1 689 ? 95.830  164.389 110.946 1.00 51.59  ? 689 LEU B CD2 1 
ATOM   9555  N N   . LYS B 1 690 ? 93.306  162.086 107.457 1.00 59.06  ? 690 LYS B N   1 
ATOM   9556  C CA  . LYS B 1 690 ? 93.142  161.491 106.125 1.00 60.16  ? 690 LYS B CA  1 
ATOM   9557  C C   . LYS B 1 690 ? 94.487  160.980 105.603 1.00 58.89  ? 690 LYS B C   1 
ATOM   9558  O O   . LYS B 1 690 ? 95.460  161.729 105.577 1.00 57.43  ? 690 LYS B O   1 
ATOM   9559  C CB  . LYS B 1 690 ? 92.506  162.512 105.168 1.00 60.92  ? 690 LYS B CB  1 
ATOM   9560  C CG  . LYS B 1 690 ? 92.147  161.877 103.816 1.00 61.74  ? 690 LYS B CG  1 
ATOM   9561  C CD  . LYS B 1 690 ? 91.565  162.918 102.857 1.00 61.97  ? 690 LYS B CD  1 
ATOM   9562  C CE  . LYS B 1 690 ? 91.388  162.314 101.466 1.00 63.99  ? 690 LYS B CE  1 
ATOM   9563  N NZ  . LYS B 1 690 ? 90.934  163.325 100.487 1.00 62.31  ? 690 LYS B NZ  1 
ATOM   9564  N N   . VAL B 1 691 ? 94.531  159.727 105.154 1.00 55.27  ? 691 VAL B N   1 
ATOM   9565  C CA  . VAL B 1 691 ? 95.737  159.074 104.608 1.00 57.78  ? 691 VAL B CA  1 
ATOM   9566  C C   . VAL B 1 691 ? 95.614  158.698 103.122 1.00 56.02  ? 691 VAL B C   1 
ATOM   9567  O O   . VAL B 1 691 ? 96.617  158.380 102.486 1.00 53.82  ? 691 VAL B O   1 
ATOM   9568  C CB  . VAL B 1 691 ? 96.162  157.866 105.471 1.00 52.48  ? 691 VAL B CB  1 
ATOM   9569  C CG1 . VAL B 1 691 ? 96.522  158.286 106.899 1.00 46.28  ? 691 VAL B CG1 1 
ATOM   9570  C CG2 . VAL B 1 691 ? 95.097  156.773 105.552 1.00 50.63  ? 691 VAL B CG2 1 
ATOM   9571  N N   . GLY B 1 692 ? 94.416  158.777 102.537 1.00 63.77  ? 692 GLY B N   1 
ATOM   9572  C CA  . GLY B 1 692 ? 94.163  158.477 101.124 1.00 64.55  ? 692 GLY B CA  1 
ATOM   9573  C C   . GLY B 1 692 ? 92.671  158.378 100.806 1.00 69.59  ? 692 GLY B C   1 
ATOM   9574  O O   . GLY B 1 692 ? 91.859  159.066 101.426 1.00 69.93  ? 692 GLY B O   1 
ATOM   9575  N N   . THR B 1 693 ? 92.294  157.490 99.879  1.00 75.77  ? 693 THR B N   1 
ATOM   9576  C CA  . THR B 1 693 ? 90.897  157.114 99.572  1.00 75.33  ? 693 THR B CA  1 
ATOM   9577  C C   . THR B 1 693 ? 90.716  155.596 99.706  1.00 74.67  ? 693 THR B C   1 
ATOM   9578  O O   . THR B 1 693 ? 91.609  154.839 99.322  1.00 75.02  ? 693 THR B O   1 
ATOM   9579  C CB  . THR B 1 693 ? 90.489  157.600 98.171  1.00 76.07  ? 693 THR B CB  1 
ATOM   9580  O OG1 . THR B 1 693 ? 90.631  159.002 98.085  1.00 75.68  ? 693 THR B OG1 1 
ATOM   9581  C CG2 . THR B 1 693 ? 89.033  157.287 97.830  1.00 75.35  ? 693 THR B CG2 1 
ATOM   9582  N N   . ARG B 1 694 ? 89.594  155.134 100.276 1.00 77.02  ? 694 ARG B N   1 
ATOM   9583  C CA  . ARG B 1 694 ? 89.392  153.719 100.648 1.00 78.69  ? 694 ARG B CA  1 
ATOM   9584  C C   . ARG B 1 694 ? 89.295  152.788 99.432  1.00 80.35  ? 694 ARG B C   1 
ATOM   9585  O O   . ARG B 1 694 ? 88.822  153.182 98.365  1.00 78.44  ? 694 ARG B O   1 
ATOM   9586  C CB  . ARG B 1 694 ? 88.148  153.557 101.541 1.00 77.78  ? 694 ARG B CB  1 
ATOM   9587  C CG  . ARG B 1 694 ? 88.246  154.365 102.842 1.00 77.72  ? 694 ARG B CG  1 
ATOM   9588  C CD  . ARG B 1 694 ? 87.061  154.103 103.777 1.00 78.66  ? 694 ARG B CD  1 
ATOM   9589  N NE  . ARG B 1 694 ? 87.138  152.772 104.407 1.00 81.21  ? 694 ARG B NE  1 
ATOM   9590  C CZ  . ARG B 1 694 ? 86.224  152.214 105.178 1.00 81.40  ? 694 ARG B CZ  1 
ATOM   9591  N NH1 . ARG B 1 694 ? 86.433  151.041 105.697 1.00 78.98  ? 694 ARG B NH1 1 
ATOM   9592  N NH2 . ARG B 1 694 ? 85.092  152.794 105.449 1.00 78.90  ? 694 ARG B NH2 1 
ATOM   9593  N N   . GLY B 1 695 ? 89.701  151.533 99.611  1.00 78.83  ? 695 GLY B N   1 
ATOM   9594  C CA  . GLY B 1 695 ? 89.646  150.504 98.571  1.00 78.52  ? 695 GLY B CA  1 
ATOM   9595  C C   . GLY B 1 695 ? 90.310  149.191 98.981  1.00 78.43  ? 695 GLY B C   1 
ATOM   9596  O O   . GLY B 1 695 ? 91.141  149.152 99.894  1.00 77.61  ? 695 GLY B O   1 
ATOM   9597  N N   . PRO B 1 699 ? 86.867  159.199 101.476 1.00 77.00  ? 699 PRO B N   1 
ATOM   9598  C CA  . PRO B 1 699 ? 88.185  159.399 102.060 1.00 78.11  ? 699 PRO B CA  1 
ATOM   9599  C C   . PRO B 1 699 ? 88.543  158.314 103.086 1.00 77.42  ? 699 PRO B C   1 
ATOM   9600  O O   . PRO B 1 699 ? 87.686  157.793 103.801 1.00 74.98  ? 699 PRO B O   1 
ATOM   9601  C CB  . PRO B 1 699 ? 88.132  160.787 102.699 1.00 76.40  ? 699 PRO B CB  1 
ATOM   9602  C CG  . PRO B 1 699 ? 86.662  160.940 103.074 1.00 75.94  ? 699 PRO B CG  1 
ATOM   9603  C CD  . PRO B 1 699 ? 85.947  160.217 101.939 1.00 76.68  ? 699 PRO B CD  1 
ATOM   9604  N N   . ASP B 1 700 ? 89.831  157.981 103.170 1.00 67.57  ? 700 ASP B N   1 
ATOM   9605  C CA  . ASP B 1 700 ? 90.390  157.064 104.169 1.00 67.15  ? 700 ASP B CA  1 
ATOM   9606  C C   . ASP B 1 700 ? 90.915  157.868 105.364 1.00 66.10  ? 700 ASP B C   1 
ATOM   9607  O O   . ASP B 1 700 ? 92.007  158.435 105.307 1.00 64.84  ? 700 ASP B O   1 
ATOM   9608  C CB  . ASP B 1 700 ? 91.481  156.208 103.503 1.00 66.65  ? 700 ASP B CB  1 
ATOM   9609  C CG  . ASP B 1 700 ? 92.026  155.077 104.379 1.00 69.39  ? 700 ASP B CG  1 
ATOM   9610  O OD1 . ASP B 1 700 ? 91.579  154.893 105.529 1.00 66.68  ? 700 ASP B OD1 1 
ATOM   9611  O OD2 . ASP B 1 700 ? 92.901  154.329 103.896 1.00 67.74  ? 700 ASP B OD2 1 
ATOM   9612  N N   . GLU B 1 701 ? 90.109  157.983 106.420 1.00 61.62  ? 701 GLU B N   1 
ATOM   9613  C CA  . GLU B 1 701 ? 90.456  158.694 107.653 1.00 61.01  ? 701 GLU B CA  1 
ATOM   9614  C C   . GLU B 1 701 ? 90.684  157.717 108.805 1.00 59.21  ? 701 GLU B C   1 
ATOM   9615  O O   . GLU B 1 701 ? 89.841  156.859 109.073 1.00 61.25  ? 701 GLU B O   1 
ATOM   9616  C CB  . GLU B 1 701 ? 89.374  159.716 108.028 1.00 62.17  ? 701 GLU B CB  1 
ATOM   9617  C CG  . GLU B 1 701 ? 89.268  160.862 107.018 1.00 62.52  ? 701 GLU B CG  1 
ATOM   9618  C CD  . GLU B 1 701 ? 88.371  161.994 107.537 1.00 64.57  ? 701 GLU B CD  1 
ATOM   9619  O OE1 . GLU B 1 701 ? 87.225  161.725 107.954 1.00 63.18  ? 701 GLU B OE1 1 
ATOM   9620  O OE2 . GLU B 1 701 ? 88.801  163.165 107.516 1.00 62.51  ? 701 GLU B OE2 1 
ATOM   9621  N N   . ARG B 1 702 ? 91.810  157.854 109.507 1.00 48.02  ? 702 ARG B N   1 
ATOM   9622  C CA  . ARG B 1 702 ? 92.238  156.938 110.574 1.00 39.04  ? 702 ARG B CA  1 
ATOM   9623  C C   . ARG B 1 702 ? 92.849  157.670 111.747 1.00 38.77  ? 702 ARG B C   1 
ATOM   9624  O O   . ARG B 1 702 ? 93.436  158.730 111.581 1.00 44.04  ? 702 ARG B O   1 
ATOM   9625  C CB  . ARG B 1 702 ? 93.282  155.950 110.047 1.00 40.84  ? 702 ARG B CB  1 
ATOM   9626  C CG  . ARG B 1 702 ? 92.847  155.241 108.772 1.00 43.13  ? 702 ARG B CG  1 
ATOM   9627  C CD  . ARG B 1 702 ? 93.785  154.081 108.519 1.00 40.16  ? 702 ARG B CD  1 
ATOM   9628  N NE  . ARG B 1 702 ? 93.617  153.578 107.163 1.00 41.94  ? 702 ARG B NE  1 
ATOM   9629  C CZ  . ARG B 1 702 ? 94.323  152.617 106.621 1.00 40.72  ? 702 ARG B CZ  1 
ATOM   9630  N NH1 . ARG B 1 702 ? 94.271  152.452 105.343 1.00 39.35  ? 702 ARG B NH1 1 
ATOM   9631  N NH2 . ARG B 1 702 ? 95.099  151.839 107.320 1.00 41.77  ? 702 ARG B NH2 1 
ATOM   9632  N N   . TRP B 1 703 ? 92.760  157.070 112.925 1.00 41.81  ? 703 TRP B N   1 
ATOM   9633  C CA  . TRP B 1 703 ? 93.533  157.490 114.087 1.00 38.11  ? 703 TRP B CA  1 
ATOM   9634  C C   . TRP B 1 703 ? 94.982  157.050 113.917 1.00 35.52  ? 703 TRP B C   1 
ATOM   9635  O O   . TRP B 1 703 ? 95.316  155.869 113.977 1.00 34.30  ? 703 TRP B O   1 
ATOM   9636  C CB  . TRP B 1 703 ? 92.881  156.972 115.360 1.00 37.41  ? 703 TRP B CB  1 
ATOM   9637  C CG  . TRP B 1 703 ? 91.652  157.751 115.689 1.00 37.16  ? 703 TRP B CG  1 
ATOM   9638  C CD1 . TRP B 1 703 ? 90.421  157.551 115.166 1.00 38.88  ? 703 TRP B CD1 1 
ATOM   9639  C CD2 . TRP B 1 703 ? 91.537  158.935 116.527 1.00 39.16  ? 703 TRP B CD2 1 
ATOM   9640  N NE1 . TRP B 1 703 ? 89.557  158.518 115.630 1.00 40.56  ? 703 TRP B NE1 1 
ATOM   9641  C CE2 . TRP B 1 703 ? 90.191  159.401 116.471 1.00 38.91  ? 703 TRP B CE2 1 
ATOM   9642  C CE3 . TRP B 1 703 ? 92.431  159.655 117.348 1.00 37.66  ? 703 TRP B CE3 1 
ATOM   9643  C CZ2 . TRP B 1 703 ? 89.754  160.523 117.185 1.00 35.37  ? 703 TRP B CZ2 1 
ATOM   9644  C CZ3 . TRP B 1 703 ? 92.001  160.776 118.079 1.00 38.85  ? 703 TRP B CZ3 1 
ATOM   9645  C CH2 . TRP B 1 703 ? 90.666  161.210 117.998 1.00 40.49  ? 703 TRP B CH2 1 
ATOM   9646  N N   . CYS B 1 704 ? 95.829  158.032 113.652 1.00 39.05  ? 704 CYS B N   1 
ATOM   9647  C CA  . CYS B 1 704 ? 97.209  157.850 113.249 1.00 32.65  ? 704 CYS B CA  1 
ATOM   9648  C C   . CYS B 1 704 ? 98.143  158.535 114.235 1.00 30.99  ? 704 CYS B C   1 
ATOM   9649  O O   . CYS B 1 704 ? 97.869  159.626 114.726 1.00 42.15  ? 704 CYS B O   1 
ATOM   9650  C CB  . CYS B 1 704 ? 97.394  158.393 111.828 1.00 33.76  ? 704 CYS B CB  1 
ATOM   9651  S SG  . CYS B 1 704 ? 97.062  157.081 110.630 1.00 52.07  ? 704 CYS B SG  1 
ATOM   9652  N N   . PHE B 1 705 ? 99.272  157.905 114.498 1.00 23.79  ? 705 PHE B N   1 
ATOM   9653  C CA  . PHE B 1 705 ? 100.275 158.370 115.438 1.00 22.82  ? 705 PHE B CA  1 
ATOM   9654  C C   . PHE B 1 705 ? 101.586 158.682 114.728 1.00 23.91  ? 705 PHE B C   1 
ATOM   9655  O O   . PHE B 1 705 ? 102.154 157.821 114.058 1.00 26.27  ? 705 PHE B O   1 
ATOM   9656  C CB  . PHE B 1 705 ? 100.395 157.288 116.496 1.00 26.86  ? 705 PHE B CB  1 
ATOM   9657  C CG  . PHE B 1 705 ? 101.357 157.558 117.624 1.00 27.04  ? 705 PHE B CG  1 
ATOM   9658  C CD1 . PHE B 1 705 ? 100.979 158.396 118.683 1.00 27.43  ? 705 PHE B CD1 1 
ATOM   9659  C CD2 . PHE B 1 705 ? 102.597 156.907 117.645 1.00 25.57  ? 705 PHE B CD2 1 
ATOM   9660  C CE1 . PHE B 1 705 ? 101.855 158.599 119.761 1.00 27.12  ? 705 PHE B CE1 1 
ATOM   9661  C CE2 . PHE B 1 705 ? 103.468 157.110 118.719 1.00 28.26  ? 705 PHE B CE2 1 
ATOM   9662  C CZ  . PHE B 1 705 ? 103.103 157.961 119.772 1.00 24.70  ? 705 PHE B CZ  1 
ATOM   9663  N N   . ARG B 1 706 ? 102.050 159.925 114.852 1.00 30.98  ? 706 ARG B N   1 
ATOM   9664  C CA  . ARG B 1 706 ? 103.273 160.423 114.230 1.00 25.36  ? 706 ARG B CA  1 
ATOM   9665  C C   . ARG B 1 706 ? 104.511 159.966 114.988 1.00 23.96  ? 706 ARG B C   1 
ATOM   9666  O O   . ARG B 1 706 ? 104.682 160.284 116.161 1.00 32.09  ? 706 ARG B O   1 
ATOM   9667  C CB  . ARG B 1 706 ? 103.169 161.948 114.119 1.00 30.40  ? 706 ARG B CB  1 
ATOM   9668  C CG  . ARG B 1 706 ? 104.334 162.564 113.346 1.00 31.63  ? 706 ARG B CG  1 
ATOM   9669  C CD  . ARG B 1 706 ? 104.137 164.066 113.149 1.00 34.00  ? 706 ARG B CD  1 
ATOM   9670  N NE  . ARG B 1 706 ? 103.082 164.346 112.165 1.00 35.80  ? 706 ARG B NE  1 
ATOM   9671  C CZ  . ARG B 1 706 ? 101.884 164.856 112.346 1.00 39.58  ? 706 ARG B CZ  1 
ATOM   9672  N NH1 . ARG B 1 706 ? 101.088 165.016 111.338 1.00 32.26  ? 706 ARG B NH1 1 
ATOM   9673  N NH2 . ARG B 1 706 ? 101.451 165.207 113.518 1.00 39.62  ? 706 ARG B NH2 1 
ATOM   9674  N N   . VAL B 1 707 ? 105.398 159.267 114.299 1.00 29.09  ? 707 VAL B N   1 
ATOM   9675  C CA  . VAL B 1 707 ? 106.704 158.825 114.792 1.00 27.48  ? 707 VAL B CA  1 
ATOM   9676  C C   . VAL B 1 707 ? 107.788 159.423 113.900 1.00 32.06  ? 707 VAL B C   1 
ATOM   9677  O O   . VAL B 1 707 ? 107.681 159.404 112.678 1.00 36.12  ? 707 VAL B O   1 
ATOM   9678  C CB  . VAL B 1 707 ? 106.793 157.291 114.846 1.00 32.19  ? 707 VAL B CB  1 
ATOM   9679  C CG1 . VAL B 1 707 ? 108.128 156.811 115.416 1.00 25.98  ? 707 VAL B CG1 1 
ATOM   9680  C CG2 . VAL B 1 707 ? 105.686 156.663 115.696 1.00 32.26  ? 707 VAL B CG2 1 
ATOM   9681  N N   . GLU B 1 708 ? 108.832 159.968 114.508 1.00 40.98  ? 708 GLU B N   1 
ATOM   9682  C CA  . GLU B 1 708 ? 109.981 160.524 113.805 1.00 31.70  ? 708 GLU B CA  1 
ATOM   9683  C C   . GLU B 1 708 ? 111.174 159.608 114.073 1.00 36.03  ? 708 GLU B C   1 
ATOM   9684  O O   . GLU B 1 708 ? 111.620 159.469 115.209 1.00 45.02  ? 708 GLU B O   1 
ATOM   9685  C CB  . GLU B 1 708 ? 110.255 161.961 114.284 1.00 35.70  ? 708 GLU B CB  1 
ATOM   9686  C CG  . GLU B 1 708 ? 109.015 162.869 114.299 1.00 37.57  ? 708 GLU B CG  1 
ATOM   9687  C CD  . GLU B 1 708 ? 109.290 164.267 114.871 1.00 46.39  ? 708 GLU B CD  1 
ATOM   9688  O OE1 . GLU B 1 708 ? 110.198 164.420 115.719 1.00 48.97  ? 708 GLU B OE1 1 
ATOM   9689  O OE2 . GLU B 1 708 ? 108.553 165.215 114.516 1.00 47.67  ? 708 GLU B OE2 1 
ATOM   9690  N N   . GLU B 1 709 ? 111.693 158.960 113.040 1.00 41.77  ? 709 GLU B N   1 
ATOM   9691  C CA  . GLU B 1 709 ? 112.878 158.110 113.117 1.00 40.39  ? 709 GLU B CA  1 
ATOM   9692  C C   . GLU B 1 709 ? 114.056 158.889 112.543 1.00 43.47  ? 709 GLU B C   1 
ATOM   9693  O O   . GLU B 1 709 ? 113.981 159.388 111.423 1.00 42.80  ? 709 GLU B O   1 
ATOM   9694  C CB  . GLU B 1 709 ? 112.646 156.791 112.355 1.00 41.51  ? 709 GLU B CB  1 
ATOM   9695  C CG  . GLU B 1 709 ? 113.903 155.902 112.332 1.00 45.40  ? 709 GLU B CG  1 
ATOM   9696  C CD  . GLU B 1 709 ? 113.779 154.609 111.506 1.00 51.18  ? 709 GLU B CD  1 
ATOM   9697  O OE1 . GLU B 1 709 ? 112.826 154.455 110.710 1.00 51.45  ? 709 GLU B OE1 1 
ATOM   9698  O OE2 . GLU B 1 709 ? 114.686 153.750 111.620 1.00 48.74  ? 709 GLU B OE2 1 
ATOM   9699  N N   . VAL B 1 710 ? 115.166 158.954 113.278 1.00 43.86  ? 710 VAL B N   1 
ATOM   9700  C CA  . VAL B 1 710 ? 116.458 159.376 112.739 1.00 40.85  ? 710 VAL B CA  1 
ATOM   9701  C C   . VAL B 1 710 ? 117.361 158.153 112.681 1.00 37.06  ? 710 VAL B C   1 
ATOM   9702  O O   . VAL B 1 710 ? 117.575 157.495 113.696 1.00 42.17  ? 710 VAL B O   1 
ATOM   9703  C CB  . VAL B 1 710 ? 117.098 160.506 113.558 1.00 39.94  ? 710 VAL B CB  1 
ATOM   9704  C CG1 . VAL B 1 710 ? 118.324 161.052 112.824 1.00 39.21  ? 710 VAL B CG1 1 
ATOM   9705  C CG2 . VAL B 1 710 ? 116.117 161.651 113.821 1.00 39.17  ? 710 VAL B CG2 1 
ATOM   9706  N N   . ASN B 1 711 ? 117.882 157.818 111.505 1.00 39.11  ? 711 ASN B N   1 
ATOM   9707  C CA  . ASN B 1 711 ? 118.672 156.606 111.301 1.00 37.09  ? 711 ASN B CA  1 
ATOM   9708  C C   . ASN B 1 711 ? 119.740 156.830 110.222 1.00 40.16  ? 711 ASN B C   1 
ATOM   9709  O O   . ASN B 1 711 ? 119.547 156.518 109.051 1.00 47.70  ? 711 ASN B O   1 
ATOM   9710  C CB  . ASN B 1 711 ? 117.702 155.453 111.000 1.00 40.55  ? 711 ASN B CB  1 
ATOM   9711  C CG  . ASN B 1 711 ? 118.332 154.081 111.131 1.00 43.15  ? 711 ASN B CG  1 
ATOM   9712  O OD1 . ASN B 1 711 ? 119.538 153.903 111.060 1.00 43.03  ? 711 ASN B OD1 1 
ATOM   9713  N ND2 . ASN B 1 711 ? 117.520 153.075 111.340 1.00 45.57  ? 711 ASN B ND2 1 
ATOM   9714  N N   . TRP B 1 712 ? 120.878 157.390 110.627 1.00 37.99  ? 712 TRP B N   1 
ATOM   9715  C CA  . TRP B 1 712 ? 122.026 157.662 109.761 1.00 37.64  ? 712 TRP B CA  1 
ATOM   9716  C C   . TRP B 1 712 ? 122.614 156.400 109.139 1.00 39.17  ? 712 TRP B C   1 
ATOM   9717  O O   . TRP B 1 712 ? 122.897 156.385 107.947 1.00 42.13  ? 712 TRP B O   1 
ATOM   9718  C CB  . TRP B 1 712 ? 123.108 158.369 110.581 1.00 41.29  ? 712 TRP B CB  1 
ATOM   9719  C CG  . TRP B 1 712 ? 122.821 159.781 110.960 1.00 39.45  ? 712 TRP B CG  1 
ATOM   9720  C CD1 . TRP B 1 712 ? 122.114 160.192 112.032 1.00 41.04  ? 712 TRP B CD1 1 
ATOM   9721  C CD2 . TRP B 1 712 ? 123.270 160.996 110.285 1.00 38.26  ? 712 TRP B CD2 1 
ATOM   9722  N NE1 . TRP B 1 712 ? 122.081 161.570 112.065 1.00 42.60  ? 712 TRP B NE1 1 
ATOM   9723  C CE2 . TRP B 1 712 ? 122.806 162.115 111.034 1.00 41.39  ? 712 TRP B CE2 1 
ATOM   9724  C CE3 . TRP B 1 712 ? 124.067 161.257 109.155 1.00 34.27  ? 712 TRP B CE3 1 
ATOM   9725  C CZ2 . TRP B 1 712 ? 123.123 163.431 110.678 1.00 40.61  ? 712 TRP B CZ2 1 
ATOM   9726  C CZ3 . TRP B 1 712 ? 124.393 162.577 108.791 1.00 34.62  ? 712 TRP B CZ3 1 
ATOM   9727  C CH2 . TRP B 1 712 ? 123.927 163.658 109.556 1.00 39.78  ? 712 TRP B CH2 1 
ATOM   9728  N N   . ALA B 1 713 ? 122.758 155.331 109.917 1.00 44.85  ? 713 ALA B N   1 
ATOM   9729  C CA  . ALA B 1 713 ? 123.329 154.076 109.446 1.00 43.61  ? 713 ALA B CA  1 
ATOM   9730  C C   . ALA B 1 713 ? 122.486 153.430 108.335 1.00 45.88  ? 713 ALA B C   1 
ATOM   9731  O O   . ALA B 1 713 ? 123.035 152.987 107.332 1.00 49.51  ? 713 ALA B O   1 
ATOM   9732  C CB  . ALA B 1 713 ? 123.506 153.147 110.650 1.00 43.41  ? 713 ALA B CB  1 
ATOM   9733  N N   . ALA B 1 714 ? 121.156 153.414 108.465 1.00 44.29  ? 714 ALA B N   1 
ATOM   9734  C CA  . ALA B 1 714 ? 120.277 152.935 107.407 1.00 40.89  ? 714 ALA B CA  1 
ATOM   9735  C C   . ALA B 1 714 ? 120.254 153.872 106.192 1.00 44.56  ? 714 ALA B C   1 
ATOM   9736  O O   . ALA B 1 714 ? 120.220 153.405 105.057 1.00 48.15  ? 714 ALA B O   1 
ATOM   9737  C CB  . ALA B 1 714 ? 118.871 152.742 107.974 1.00 42.47  ? 714 ALA B CB  1 
ATOM   9738  N N   . TRP B 1 715 ? 120.294 155.187 106.406 1.00 41.71  ? 715 TRP B N   1 
ATOM   9739  C CA  . TRP B 1 715 ? 120.257 156.175 105.330 1.00 42.93  ? 715 TRP B CA  1 
ATOM   9740  C C   . TRP B 1 715 ? 121.521 156.177 104.472 1.00 42.69  ? 715 TRP B C   1 
ATOM   9741  O O   . TRP B 1 715 ? 121.420 156.092 103.252 1.00 46.29  ? 715 TRP B O   1 
ATOM   9742  C CB  . TRP B 1 715 ? 119.976 157.551 105.926 1.00 38.51  ? 715 TRP B CB  1 
ATOM   9743  C CG  . TRP B 1 715 ? 120.119 158.695 104.979 1.00 38.24  ? 715 TRP B CG  1 
ATOM   9744  C CD1 . TRP B 1 715 ? 119.330 158.940 103.915 1.00 36.87  ? 715 TRP B CD1 1 
ATOM   9745  C CD2 . TRP B 1 715 ? 121.123 159.749 104.983 1.00 41.69  ? 715 TRP B CD2 1 
ATOM   9746  N NE1 . TRP B 1 715 ? 119.758 160.086 103.277 1.00 40.10  ? 715 TRP B NE1 1 
ATOM   9747  C CE2 . TRP B 1 715 ? 120.848 160.641 103.910 1.00 39.79  ? 715 TRP B CE2 1 
ATOM   9748  C CE3 . TRP B 1 715 ? 122.224 160.057 105.807 1.00 34.42  ? 715 TRP B CE3 1 
ATOM   9749  C CZ2 . TRP B 1 715 ? 121.601 161.796 103.675 1.00 38.79  ? 715 TRP B CZ2 1 
ATOM   9750  C CZ3 . TRP B 1 715 ? 122.990 161.208 105.581 1.00 38.19  ? 715 TRP B CZ3 1 
ATOM   9751  C CH2 . TRP B 1 715 ? 122.678 162.083 104.529 1.00 38.69  ? 715 TRP B CH2 1 
ATOM   9752  N N   . GLU B 1 716 ? 122.714 156.193 105.067 1.00 49.29  ? 716 GLU B N   1 
ATOM   9753  C CA  . GLU B 1 716 ? 123.974 156.239 104.315 1.00 51.15  ? 716 GLU B CA  1 
ATOM   9754  C C   . GLU B 1 716 ? 124.171 155.040 103.378 1.00 55.42  ? 716 GLU B C   1 
ATOM   9755  O O   . GLU B 1 716 ? 124.701 155.189 102.280 1.00 58.35  ? 716 GLU B O   1 
ATOM   9756  C CB  . GLU B 1 716 ? 125.160 156.346 105.276 1.00 50.87  ? 716 GLU B CB  1 
ATOM   9757  C CG  . GLU B 1 716 ? 125.283 157.758 105.857 1.00 56.54  ? 716 GLU B CG  1 
ATOM   9758  C CD  . GLU B 1 716 ? 126.652 157.987 106.511 1.00 57.04  ? 716 GLU B CD  1 
ATOM   9759  O OE1 . GLU B 1 716 ? 127.145 157.080 107.213 1.00 55.54  ? 716 GLU B OE1 1 
ATOM   9760  O OE2 . GLU B 1 716 ? 127.242 159.067 106.284 1.00 56.04  ? 716 GLU B OE2 1 
ATOM   9761  N N   . LYS B 1 717 ? 123.658 153.862 103.753 1.00 52.19  ? 717 LYS B N   1 
ATOM   9762  C CA  . LYS B 1 717 ? 123.662 152.658 102.908 1.00 51.99  ? 717 LYS B CA  1 
ATOM   9763  C C   . LYS B 1 717 ? 122.826 152.799 101.632 1.00 54.51  ? 717 LYS B C   1 
ATOM   9764  O O   . LYS B 1 717 ? 123.060 152.056 100.682 1.00 59.27  ? 717 LYS B O   1 
ATOM   9765  C CB  . LYS B 1 717 ? 123.191 151.458 103.740 1.00 52.36  ? 717 LYS B CB  1 
ATOM   9766  C CG  . LYS B 1 717 ? 124.226 151.091 104.814 1.00 55.04  ? 717 LYS B CG  1 
ATOM   9767  C CD  . LYS B 1 717 ? 123.701 149.999 105.750 1.00 56.54  ? 717 LYS B CD  1 
ATOM   9768  C CE  . LYS B 1 717 ? 124.700 149.789 106.891 1.00 56.49  ? 717 LYS B CE  1 
ATOM   9769  N NZ  . LYS B 1 717 ? 124.257 148.727 107.822 1.00 55.74  ? 717 LYS B NZ  1 
ATOM   9770  N N   . THR B 1 718 ? 121.893 153.748 101.569 1.00 49.56  ? 718 THR B N   1 
ATOM   9771  C CA  . THR B 1 718 ? 121.078 154.027 100.369 1.00 50.56  ? 718 THR B CA  1 
ATOM   9772  C C   . THR B 1 718 ? 121.759 154.952 99.355  1.00 52.71  ? 718 THR B C   1 
ATOM   9773  O O   . THR B 1 718 ? 121.305 155.043 98.213  1.00 54.89  ? 718 THR B O   1 
ATOM   9774  C CB  . THR B 1 718 ? 119.698 154.614 100.711 1.00 54.54  ? 718 THR B CB  1 
ATOM   9775  O OG1 . THR B 1 718 ? 119.771 155.946 101.165 1.00 53.65  ? 718 THR B OG1 1 
ATOM   9776  C CG2 . THR B 1 718 ? 118.952 153.796 101.760 1.00 53.69  ? 718 THR B CG2 1 
ATOM   9777  N N   . LEU B 1 719 ? 122.827 155.655 99.733  1.00 49.98  ? 719 LEU B N   1 
ATOM   9778  C CA  . LEU B 1 719 ? 123.446 156.689 98.900  1.00 52.53  ? 719 LEU B CA  1 
ATOM   9779  C C   . LEU B 1 719 ? 124.281 156.072 97.772  1.00 55.35  ? 719 LEU B C   1 
ATOM   9780  O O   . LEU B 1 719 ? 124.396 156.645 96.686  1.00 54.07  ? 719 LEU B O   1 
ATOM   9781  C CB  . LEU B 1 719 ? 124.279 157.648 99.777  1.00 54.46  ? 719 LEU B CB  1 
ATOM   9782  C CG  . LEU B 1 719 ? 123.520 158.273 100.964 1.00 52.49  ? 719 LEU B CG  1 
ATOM   9783  C CD1 . LEU B 1 719 ? 124.435 159.241 101.710 1.00 50.33  ? 719 LEU B CD1 1 
ATOM   9784  C CD2 . LEU B 1 719 ? 122.260 159.015 100.540 1.00 48.63  ? 719 LEU B CD2 1 
ATOM   9785  N N   . ARG C 1 74  ? 90.955  185.273 88.724  1.00 118.61 ? 74  ARG C N   1 
ATOM   9786  C CA  . ARG C 1 74  ? 92.023  185.389 89.755  1.00 119.70 ? 74  ARG C CA  1 
ATOM   9787  C C   . ARG C 1 74  ? 92.888  184.128 89.758  1.00 119.77 ? 74  ARG C C   1 
ATOM   9788  O O   . ARG C 1 74  ? 92.681  183.266 88.878  1.00 119.17 ? 74  ARG C O   1 
ATOM   9789  C CB  . ARG C 1 74  ? 91.418  185.600 91.146  1.00 119.43 ? 74  ARG C CB  1 
ATOM   9790  C CG  . ARG C 1 74  ? 90.892  184.332 91.803  1.00 118.70 ? 74  ARG C CG  1 
ATOM   9791  C CD  . ARG C 1 74  ? 89.907  184.638 92.913  1.00 118.82 ? 74  ARG C CD  1 
ATOM   9792  N NE  . ARG C 1 74  ? 90.384  185.658 93.835  1.00 119.66 ? 74  ARG C NE  1 
ATOM   9793  C CZ  . ARG C 1 74  ? 91.017  185.408 94.975  1.00 119.51 ? 74  ARG C CZ  1 
ATOM   9794  N NH1 . ARG C 1 74  ? 91.411  186.408 95.747  1.00 119.04 ? 74  ARG C NH1 1 
ATOM   9795  N NH2 . ARG C 1 74  ? 91.253  184.161 95.343  1.00 118.94 ? 74  ARG C NH2 1 
ATOM   9796  N N   . PHE C 1 75  ? 93.804  184.027 90.725  1.00 116.99 ? 75  PHE C N   1 
ATOM   9797  C CA  . PHE C 1 75  ? 94.698  182.862 90.828  1.00 116.91 ? 75  PHE C CA  1 
ATOM   9798  C C   . PHE C 1 75  ? 95.179  182.710 92.281  1.00 116.45 ? 75  PHE C C   1 
ATOM   9799  O O   . PHE C 1 75  ? 95.612  183.678 92.899  1.00 115.50 ? 75  PHE C O   1 
ATOM   9800  C CB  . PHE C 1 75  ? 95.871  183.000 89.846  1.00 116.08 ? 75  PHE C CB  1 
ATOM   9801  C CG  . PHE C 1 75  ? 96.398  181.677 89.317  1.00 115.97 ? 75  PHE C CG  1 
ATOM   9802  C CD1 . PHE C 1 75  ? 96.955  180.711 90.176  1.00 115.54 ? 75  PHE C CD1 1 
ATOM   9803  C CD2 . PHE C 1 75  ? 96.341  181.418 87.936  1.00 115.49 ? 75  PHE C CD2 1 
ATOM   9804  C CE1 . PHE C 1 75  ? 97.461  179.508 89.659  1.00 115.90 ? 75  PHE C CE1 1 
ATOM   9805  C CE2 . PHE C 1 75  ? 96.875  180.230 87.417  1.00 115.28 ? 75  PHE C CE2 1 
ATOM   9806  C CZ  . PHE C 1 75  ? 97.437  179.271 88.278  1.00 115.32 ? 75  PHE C CZ  1 
ATOM   9807  N N   . ASP C 1 76  ? 95.098  181.510 92.850  1.00 114.73 ? 76  ASP C N   1 
ATOM   9808  C CA  . ASP C 1 76  ? 95.158  181.317 94.304  1.00 114.26 ? 76  ASP C CA  1 
ATOM   9809  C C   . ASP C 1 76  ? 95.982  180.080 94.705  1.00 115.33 ? 76  ASP C C   1 
ATOM   9810  O O   . ASP C 1 76  ? 96.227  179.187 93.895  1.00 114.72 ? 76  ASP C O   1 
ATOM   9811  C CB  . ASP C 1 76  ? 93.714  181.267 94.836  1.00 113.94 ? 76  ASP C CB  1 
ATOM   9812  C CG  . ASP C 1 76  ? 93.560  181.822 96.255  1.00 115.37 ? 76  ASP C CG  1 
ATOM   9813  O OD1 . ASP C 1 76  ? 94.564  181.891 96.997  1.00 115.09 ? 76  ASP C OD1 1 
ATOM   9814  O OD2 . ASP C 1 76  ? 92.423  182.205 96.606  1.00 115.34 ? 76  ASP C OD2 1 
ATOM   9815  N N   . ARG C 1 77  ? 96.426  180.043 95.967  1.00 109.43 ? 77  ARG C N   1 
ATOM   9816  C CA  . ARG C 1 77  ? 97.415  179.089 96.498  1.00 107.82 ? 77  ARG C CA  1 
ATOM   9817  C C   . ARG C 1 77  ? 97.041  177.626 96.272  1.00 107.81 ? 77  ARG C C   1 
ATOM   9818  O O   . ARG C 1 77  ? 97.864  176.858 95.784  1.00 108.19 ? 77  ARG C O   1 
ATOM   9819  C CB  . ARG C 1 77  ? 97.649  179.406 97.986  1.00 107.25 ? 77  ARG C CB  1 
ATOM   9820  C CG  . ARG C 1 77  ? 98.391  178.292 98.734  1.00 107.65 ? 77  ARG C CG  1 
ATOM   9821  C CD  . ARG C 1 77  ? 99.019  178.743 100.054 1.00 107.52 ? 77  ARG C CD  1 
ATOM   9822  N NE  . ARG C 1 77  ? 98.113  179.536 100.902 1.00 108.01 ? 77  ARG C NE  1 
ATOM   9823  C CZ  . ARG C 1 77  ? 97.495  179.157 102.004 1.00 108.37 ? 77  ARG C CZ  1 
ATOM   9824  N NH1 . ARG C 1 77  ? 96.871  180.034 102.729 1.00 108.42 ? 77  ARG C NH1 1 
ATOM   9825  N NH2 . ARG C 1 77  ? 97.464  177.921 102.401 1.00 107.36 ? 77  ARG C NH2 1 
ATOM   9826  N N   . ASP C 1 78  ? 95.810  177.238 96.590  1.00 109.09 ? 78  ASP C N   1 
ATOM   9827  C CA  . ASP C 1 78  ? 95.364  175.843 96.489  1.00 109.11 ? 78  ASP C CA  1 
ATOM   9828  C C   . ASP C 1 78  ? 95.292  175.338 95.036  1.00 108.60 ? 78  ASP C C   1 
ATOM   9829  O O   . ASP C 1 78  ? 95.534  174.161 94.781  1.00 107.75 ? 78  ASP C O   1 
ATOM   9830  C CB  . ASP C 1 78  ? 94.018  175.679 97.208  1.00 109.08 ? 78  ASP C CB  1 
ATOM   9831  C CG  . ASP C 1 78  ? 94.077  176.053 98.696  1.00 108.73 ? 78  ASP C CG  1 
ATOM   9832  O OD1 . ASP C 1 78  ? 95.133  175.870 99.334  1.00 108.59 ? 78  ASP C OD1 1 
ATOM   9833  O OD2 . ASP C 1 78  ? 93.051  176.521 99.231  1.00 108.76 ? 78  ASP C OD2 1 
ATOM   9834  N N   . ARG C 1 79  ? 95.029  176.230 94.069  1.00 111.67 ? 79  ARG C N   1 
ATOM   9835  C CA  . ARG C 1 79  ? 95.195  175.943 92.634  1.00 113.14 ? 79  ARG C CA  1 
ATOM   9836  C C   . ARG C 1 79  ? 96.675  175.820 92.304  1.00 113.16 ? 79  ARG C C   1 
ATOM   9837  O O   . ARG C 1 79  ? 97.110  174.787 91.796  1.00 112.36 ? 79  ARG C O   1 
ATOM   9838  C CB  . ARG C 1 79  ? 94.492  177.028 91.790  1.00 113.00 ? 79  ARG C CB  1 
ATOM   9839  C CG  . ARG C 1 79  ? 94.712  176.881 90.277  1.00 112.19 ? 79  ARG C CG  1 
ATOM   9840  C CD  . ARG C 1 79  ? 93.989  177.992 89.502  1.00 111.84 ? 79  ARG C CD  1 
ATOM   9841  N NE  . ARG C 1 79  ? 94.445  178.062 88.099  1.00 113.72 ? 79  ARG C NE  1 
ATOM   9842  C CZ  . ARG C 1 79  ? 93.717  177.993 87.002  1.00 113.09 ? 79  ARG C CZ  1 
ATOM   9843  N NH1 . ARG C 1 79  ? 94.278  178.064 85.833  1.00 112.24 ? 79  ARG C NH1 1 
ATOM   9844  N NH2 . ARG C 1 79  ? 92.426  177.865 87.034  1.00 112.29 ? 79  ARG C NH2 1 
ATOM   9845  N N   . LEU C 1 80  ? 97.476  176.836 92.637  1.00 109.89 ? 80  LEU C N   1 
ATOM   9846  C CA  . LEU C 1 80  ? 98.903  176.919 92.306  1.00 108.95 ? 80  LEU C CA  1 
ATOM   9847  C C   . LEU C 1 80  ? 99.712  175.715 92.806  1.00 108.06 ? 80  LEU C C   1 
ATOM   9848  O O   . LEU C 1 80  ? 100.423 175.079 92.032  1.00 108.57 ? 80  LEU C O   1 
ATOM   9849  C CB  . LEU C 1 80  ? 99.449  178.245 92.872  1.00 108.09 ? 80  LEU C CB  1 
ATOM   9850  C CG  . LEU C 1 80  ? 100.947 178.465 92.624  1.00 108.19 ? 80  LEU C CG  1 
ATOM   9851  C CD1 . LEU C 1 80  ? 101.288 178.455 91.139  1.00 108.96 ? 80  LEU C CD1 1 
ATOM   9852  C CD2 . LEU C 1 80  ? 101.359 179.808 93.208  1.00 107.98 ? 80  LEU C CD2 1 
ATOM   9853  N N   . PHE C 1 81  ? 99.569  175.354 94.080  1.00 101.81 ? 81  PHE C N   1 
ATOM   9854  C CA  . PHE C 1 81  ? 100.224 174.181 94.671  1.00 101.83 ? 81  PHE C CA  1 
ATOM   9855  C C   . PHE C 1 81  ? 99.827  172.861 93.991  1.00 103.63 ? 81  PHE C C   1 
ATOM   9856  O O   . PHE C 1 81  ? 100.592 171.896 94.024  1.00 102.72 ? 81  PHE C O   1 
ATOM   9857  C CB  . PHE C 1 81  ? 99.877  174.117 96.160  1.00 100.91 ? 81  PHE C CB  1 
ATOM   9858  C CG  . PHE C 1 81  ? 100.529 175.141 97.071  1.00 102.04 ? 81  PHE C CG  1 
ATOM   9859  C CD1 . PHE C 1 81  ? 101.452 176.105 96.610  1.00 101.54 ? 81  PHE C CD1 1 
ATOM   9860  C CD2 . PHE C 1 81  ? 100.228 175.079 98.443  1.00 102.30 ? 81  PHE C CD2 1 
ATOM   9861  C CE1 . PHE C 1 81  ? 102.074 176.975 97.520  1.00 101.23 ? 81  PHE C CE1 1 
ATOM   9862  C CE2 . PHE C 1 81  ? 100.856 175.948 99.349  1.00 101.18 ? 81  PHE C CE2 1 
ATOM   9863  C CZ  . PHE C 1 81  ? 101.790 176.887 98.890  1.00 101.26 ? 81  PHE C CZ  1 
ATOM   9864  N N   . SER C 1 82  ? 98.659  172.803 93.350  1.00 107.93 ? 82  SER C N   1 
ATOM   9865  C CA  . SER C 1 82  ? 98.254  171.635 92.564  1.00 107.33 ? 82  SER C CA  1 
ATOM   9866  C C   . SER C 1 82  ? 98.928  171.627 91.185  1.00 106.80 ? 82  SER C C   1 
ATOM   9867  O O   . SER C 1 82  ? 99.422  170.589 90.747  1.00 106.41 ? 82  SER C O   1 
ATOM   9868  C CB  . SER C 1 82  ? 96.725  171.609 92.451  1.00 107.69 ? 82  SER C CB  1 
ATOM   9869  O OG  . SER C 1 82  ? 96.259  170.355 91.992  1.00 107.59 ? 82  SER C OG  1 
ATOM   9870  N N   . VAL C 1 83  ? 99.070  172.802 90.557  1.00 105.97 ? 83  VAL C N   1 
ATOM   9871  C CA  . VAL C 1 83  ? 99.795  172.972 89.285  1.00 106.99 ? 83  VAL C CA  1 
ATOM   9872  C C   . VAL C 1 83  ? 101.284 172.647 89.420  1.00 107.18 ? 83  VAL C C   1 
ATOM   9873  O O   . VAL C 1 83  ? 101.807 171.899 88.602  1.00 106.68 ? 83  VAL C O   1 
ATOM   9874  C CB  . VAL C 1 83  ? 99.625  174.392 88.710  1.00 107.33 ? 83  VAL C CB  1 
ATOM   9875  C CG1 . VAL C 1 83  ? 100.354 174.551 87.370  1.00 107.66 ? 83  VAL C CG1 1 
ATOM   9876  C CG2 . VAL C 1 83  ? 98.154  174.716 88.467  1.00 107.11 ? 83  VAL C CG2 1 
ATOM   9877  N N   . VAL C 1 84  ? 101.981 173.143 90.452  1.00 100.60 ? 84  VAL C N   1 
ATOM   9878  C CA  . VAL C 1 84  ? 103.438 172.924 90.579  1.00 99.16  ? 84  VAL C CA  1 
ATOM   9879  C C   . VAL C 1 84  ? 103.847 171.457 90.766  1.00 98.71  ? 84  VAL C C   1 
ATOM   9880  O O   . VAL C 1 84  ? 105.009 171.124 90.560  1.00 98.07  ? 84  VAL C O   1 
ATOM   9881  C CB  . VAL C 1 84  ? 104.092 173.797 91.663  1.00 97.82  ? 84  VAL C CB  1 
ATOM   9882  C CG1 . VAL C 1 84  ? 103.798 175.283 91.480  1.00 97.74  ? 84  VAL C CG1 1 
ATOM   9883  C CG2 . VAL C 1 84  ? 103.715 173.388 93.083  1.00 97.36  ? 84  VAL C CG2 1 
ATOM   9884  N N   . SER C 1 85  ? 102.923 170.564 91.127  1.00 102.32 ? 85  SER C N   1 
ATOM   9885  C CA  . SER C 1 85  ? 103.156 169.114 91.187  1.00 102.53 ? 85  SER C CA  1 
ATOM   9886  C C   . SER C 1 85  ? 102.859 168.375 89.860  1.00 103.46 ? 85  SER C C   1 
ATOM   9887  O O   . SER C 1 85  ? 103.284 167.231 89.681  1.00 102.75 ? 85  SER C O   1 
ATOM   9888  C CB  . SER C 1 85  ? 102.342 168.542 92.355  1.00 101.12 ? 85  SER C CB  1 
ATOM   9889  O OG  . SER C 1 85  ? 102.639 167.181 92.583  1.00 101.53 ? 85  SER C OG  1 
ATOM   9890  N N   . ARG C 1 86  ? 102.215 169.055 88.893  1.00 109.96 ? 86  ARG C N   1 
ATOM   9891  C CA  . ARG C 1 86  ? 101.874 168.430 87.572  1.00 111.01 ? 86  ARG C CA  1 
ATOM   9892  C C   . ARG C 1 86  ? 103.003 168.614 86.558  1.00 112.11 ? 86  ARG C C   1 
ATOM   9893  O O   . ARG C 1 86  ? 103.770 169.587 86.691  1.00 110.05 ? 86  ARG C O   1 
ATOM   9894  C CB  . ARG C 1 86  ? 100.555 168.995 87.000  1.00 111.50 ? 86  ARG C CB  1 
ATOM   9895  C CG  . ARG C 1 86  ? 99.342  168.260 87.578  1.00 110.38 ? 86  ARG C CG  1 
ATOM   9896  C CD  . ARG C 1 86  ? 98.024  168.774 87.029  1.00 110.85 ? 86  ARG C CD  1 
ATOM   9897  N NE  . ARG C 1 86  ? 97.727  170.144 87.424  1.00 111.18 ? 86  ARG C NE  1 
ATOM   9898  C CZ  . ARG C 1 86  ? 97.078  170.481 88.532  1.00 110.34 ? 86  ARG C CZ  1 
ATOM   9899  N NH1 . ARG C 1 86  ? 96.847  171.754 88.803  1.00 110.51 ? 86  ARG C NH1 1 
ATOM   9900  N NH2 . ARG C 1 86  ? 96.663  169.546 89.367  1.00 109.54 ? 86  ARG C NH2 1 
ATOM   9901  N N   . GLY C 1 87  ? 103.086 167.710 85.587  1.00 117.59 ? 87  GLY C N   1 
ATOM   9902  C CA  . GLY C 1 87  ? 104.078 167.728 84.504  1.00 116.19 ? 87  GLY C CA  1 
ATOM   9903  C C   . GLY C 1 87  ? 103.808 168.755 83.393  1.00 116.91 ? 87  GLY C C   1 
ATOM   9904  O O   . GLY C 1 87  ? 104.690 169.019 82.580  1.00 116.95 ? 87  GLY C O   1 
ATOM   9905  N N   . VAL C 1 88  ? 102.612 169.354 83.362  1.00 119.52 ? 88  VAL C N   1 
ATOM   9906  C CA  . VAL C 1 88  ? 102.247 170.448 82.444  1.00 120.18 ? 88  VAL C CA  1 
ATOM   9907  C C   . VAL C 1 88  ? 102.119 171.783 83.202  1.00 119.70 ? 88  VAL C C   1 
ATOM   9908  O O   . VAL C 1 88  ? 101.286 171.895 84.102  1.00 118.63 ? 88  VAL C O   1 
ATOM   9909  C CB  . VAL C 1 88  ? 100.962 170.135 81.647  1.00 119.64 ? 88  VAL C CB  1 
ATOM   9910  C CG1 . VAL C 1 88  ? 101.276 169.175 80.501  1.00 118.55 ? 88  VAL C CG1 1 
ATOM   9911  C CG2 . VAL C 1 88  ? 99.815  169.535 82.468  1.00 118.97 ? 88  VAL C CG2 1 
ATOM   9912  N N   . PRO C 1 89  ? 102.899 172.821 82.850  1.00 117.63 ? 89  PRO C N   1 
ATOM   9913  C CA  . PRO C 1 89  ? 102.840 174.131 83.503  1.00 117.44 ? 89  PRO C CA  1 
ATOM   9914  C C   . PRO C 1 89  ? 101.760 175.082 82.951  1.00 118.00 ? 89  PRO C C   1 
ATOM   9915  O O   . PRO C 1 89  ? 101.571 176.162 83.500  1.00 117.15 ? 89  PRO C O   1 
ATOM   9916  C CB  . PRO C 1 89  ? 104.233 174.718 83.295  1.00 115.87 ? 89  PRO C CB  1 
ATOM   9917  C CG  . PRO C 1 89  ? 104.643 174.168 81.932  1.00 115.67 ? 89  PRO C CG  1 
ATOM   9918  C CD  . PRO C 1 89  ? 104.035 172.769 81.937  1.00 115.86 ? 89  PRO C CD  1 
ATOM   9919  N N   . GLU C 1 90  ? 101.051 174.740 81.870  1.00 117.58 ? 90  GLU C N   1 
ATOM   9920  C CA  . GLU C 1 90  ? 100.170 175.695 81.177  1.00 117.59 ? 90  GLU C CA  1 
ATOM   9921  C C   . GLU C 1 90  ? 99.021  176.240 82.042  1.00 117.74 ? 90  GLU C C   1 
ATOM   9922  O O   . GLU C 1 90  ? 98.531  177.347 81.818  1.00 117.52 ? 90  GLU C O   1 
ATOM   9923  C CB  . GLU C 1 90  ? 99.595  175.034 79.911  1.00 117.25 ? 90  GLU C CB  1 
ATOM   9924  C CG  . GLU C 1 90  ? 100.644 174.460 78.941  1.00 117.18 ? 90  GLU C CG  1 
ATOM   9925  C CD  . GLU C 1 90  ? 101.650 175.482 78.386  1.00 117.73 ? 90  GLU C CD  1 
ATOM   9926  O OE1 . GLU C 1 90  ? 101.386 176.705 78.423  1.00 117.23 ? 90  GLU C OE1 1 
ATOM   9927  O OE2 . GLU C 1 90  ? 102.706 175.053 77.877  1.00 117.08 ? 90  GLU C OE2 1 
ATOM   9928  N N   . GLU C 1 91  ? 98.610  175.503 83.076  1.00 114.74 ? 91  GLU C N   1 
ATOM   9929  C CA  . GLU C 1 91  ? 97.569  175.924 84.024  1.00 115.05 ? 91  GLU C CA  1 
ATOM   9930  C C   . GLU C 1 91  ? 97.979  177.156 84.861  1.00 114.93 ? 91  GLU C C   1 
ATOM   9931  O O   . GLU C 1 91  ? 97.117  177.797 85.464  1.00 114.87 ? 91  GLU C O   1 
ATOM   9932  C CB  . GLU C 1 91  ? 97.162  174.703 84.868  1.00 114.36 ? 91  GLU C CB  1 
ATOM   9933  C CG  . GLU C 1 91  ? 95.881  174.918 85.691  1.00 114.52 ? 91  GLU C CG  1 
ATOM   9934  C CD  . GLU C 1 91  ? 95.309  173.631 86.314  1.00 114.80 ? 91  GLU C CD  1 
ATOM   9935  O OE1 . GLU C 1 91  ? 95.948  172.555 86.256  1.00 114.73 ? 91  GLU C OE1 1 
ATOM   9936  O OE2 . GLU C 1 91  ? 94.202  173.696 86.885  1.00 113.93 ? 91  GLU C OE2 1 
ATOM   9937  N N   . LEU C 1 92  ? 99.260  177.561 84.839  1.00 114.17 ? 92  LEU C N   1 
ATOM   9938  C CA  . LEU C 1 92  ? 99.744  178.844 85.368  1.00 114.97 ? 92  LEU C CA  1 
ATOM   9939  C C   . LEU C 1 92  ? 99.226  180.072 84.592  1.00 114.75 ? 92  LEU C C   1 
ATOM   9940  O O   . LEU C 1 92  ? 99.354  181.194 85.078  1.00 114.30 ? 92  LEU C O   1 
ATOM   9941  C CB  . LEU C 1 92  ? 101.286 178.883 85.358  1.00 115.20 ? 92  LEU C CB  1 
ATOM   9942  C CG  . LEU C 1 92  ? 102.016 177.853 86.235  1.00 115.12 ? 92  LEU C CG  1 
ATOM   9943  C CD1 . LEU C 1 92  ? 103.509 177.991 85.989  1.00 113.63 ? 92  LEU C CD1 1 
ATOM   9944  C CD2 . LEU C 1 92  ? 101.760 178.048 87.726  1.00 113.56 ? 92  LEU C CD2 1 
ATOM   9945  N N   . THR C 1 93  ? 98.673  179.907 83.387  1.00 116.02 ? 93  THR C N   1 
ATOM   9946  C CA  . THR C 1 93  ? 98.168  181.040 82.584  1.00 115.27 ? 93  THR C CA  1 
ATOM   9947  C C   . THR C 1 93  ? 97.106  181.849 83.341  1.00 116.21 ? 93  THR C C   1 
ATOM   9948  O O   . THR C 1 93  ? 96.154  181.298 83.893  1.00 116.61 ? 93  THR C O   1 
ATOM   9949  C CB  . THR C 1 93  ? 97.640  180.584 81.216  1.00 114.55 ? 93  THR C CB  1 
ATOM   9950  O OG1 . THR C 1 93  ? 96.844  179.424 81.304  1.00 114.62 ? 93  THR C OG1 1 
ATOM   9951  C CG2 . THR C 1 93  ? 98.783  180.278 80.257  1.00 114.86 ? 93  THR C CG2 1 
ATOM   9952  N N   . GLY C 1 94  ? 97.290  183.171 83.405  1.00 116.70 ? 94  GLY C N   1 
ATOM   9953  C CA  . GLY C 1 94  ? 96.502  184.090 84.238  1.00 116.50 ? 94  GLY C CA  1 
ATOM   9954  C C   . GLY C 1 94  ? 97.165  184.494 85.565  1.00 117.33 ? 94  GLY C C   1 
ATOM   9955  O O   . GLY C 1 94  ? 96.749  185.486 86.170  1.00 117.01 ? 94  GLY C O   1 
ATOM   9956  N N   . LEU C 1 95  ? 98.179  183.758 86.046  1.00 117.26 ? 95  LEU C N   1 
ATOM   9957  C CA  . LEU C 1 95  ? 98.840  184.022 87.337  1.00 116.27 ? 95  LEU C CA  1 
ATOM   9958  C C   . LEU C 1 95  ? 99.607  185.353 87.345  1.00 115.86 ? 95  LEU C C   1 
ATOM   9959  O O   . LEU C 1 95  ? 99.426  186.148 88.263  1.00 115.25 ? 95  LEU C O   1 
ATOM   9960  C CB  . LEU C 1 95  ? 99.755  182.833 87.686  1.00 115.55 ? 95  LEU C CB  1 
ATOM   9961  C CG  . LEU C 1 95  ? 100.577 182.960 88.981  1.00 116.35 ? 95  LEU C CG  1 
ATOM   9962  C CD1 . LEU C 1 95  ? 99.721  183.142 90.231  1.00 115.36 ? 95  LEU C CD1 1 
ATOM   9963  C CD2 . LEU C 1 95  ? 101.389 181.683 89.158  1.00 115.43 ? 95  LEU C CD2 1 
ATOM   9964  N N   . LEU C 1 96  ? 100.417 185.611 86.319  1.00 116.63 ? 96  LEU C N   1 
ATOM   9965  C CA  . LEU C 1 96  ? 101.151 186.869 86.199  1.00 117.64 ? 96  LEU C CA  1 
ATOM   9966  C C   . LEU C 1 96  ? 100.193 188.069 86.117  1.00 118.75 ? 96  LEU C C   1 
ATOM   9967  O O   . LEU C 1 96  ? 100.413 189.073 86.791  1.00 118.59 ? 96  LEU C O   1 
ATOM   9968  C CB  . LEU C 1 96  ? 102.083 186.773 84.981  1.00 117.16 ? 96  LEU C CB  1 
ATOM   9969  C CG  . LEU C 1 96  ? 102.883 188.053 84.690  1.00 117.58 ? 96  LEU C CG  1 
ATOM   9970  C CD1 . LEU C 1 96  ? 103.800 188.448 85.846  1.00 116.49 ? 96  LEU C CD1 1 
ATOM   9971  C CD2 . LEU C 1 96  ? 103.729 187.828 83.441  1.00 116.98 ? 96  LEU C CD2 1 
ATOM   9972  N N   . GLU C 1 97  ? 99.101  187.960 85.354  1.00 118.70 ? 97  GLU C N   1 
ATOM   9973  C CA  . GLU C 1 97  ? 98.062  188.982 85.268  1.00 118.25 ? 97  GLU C CA  1 
ATOM   9974  C C   . GLU C 1 97  ? 97.414  189.252 86.634  1.00 118.29 ? 97  GLU C C   1 
ATOM   9975  O O   . GLU C 1 97  ? 97.291  190.409 87.037  1.00 117.53 ? 97  GLU C O   1 
ATOM   9976  C CB  . GLU C 1 97  ? 96.994  188.580 84.238  1.00 118.30 ? 97  GLU C CB  1 
ATOM   9977  C CG  . GLU C 1 97  ? 97.528  188.415 82.805  1.00 118.56 ? 97  GLU C CG  1 
ATOM   9978  C CD  . GLU C 1 97  ? 97.891  186.968 82.424  1.00 118.47 ? 97  GLU C CD  1 
ATOM   9979  O OE1 . GLU C 1 97  ? 98.545  186.264 83.225  1.00 117.38 ? 97  GLU C OE1 1 
ATOM   9980  O OE2 . GLU C 1 97  ? 97.526  186.544 81.309  1.00 118.49 ? 97  GLU C OE2 1 
ATOM   9981  N N   . TYR C 1 98  ? 97.053  188.209 87.385  1.00 119.30 ? 98  TYR C N   1 
ATOM   9982  C CA  . TYR C 1 98  ? 96.439  188.374 88.703  1.00 119.54 ? 98  TYR C CA  1 
ATOM   9983  C C   . TYR C 1 98  ? 97.410  188.936 89.752  1.00 119.53 ? 98  TYR C C   1 
ATOM   9984  O O   . TYR C 1 98  ? 97.057  189.861 90.482  1.00 119.13 ? 98  TYR C O   1 
ATOM   9985  C CB  . TYR C 1 98  ? 95.837  187.046 89.166  1.00 118.86 ? 98  TYR C CB  1 
ATOM   9986  C CG  . TYR C 1 98  ? 95.060  187.183 90.456  1.00 119.31 ? 98  TYR C CG  1 
ATOM   9987  C CD1 . TYR C 1 98  ? 93.873  187.936 90.482  1.00 119.44 ? 98  TYR C CD1 1 
ATOM   9988  C CD2 . TYR C 1 98  ? 95.536  186.596 91.641  1.00 119.34 ? 98  TYR C CD2 1 
ATOM   9989  C CE1 . TYR C 1 98  ? 93.159  188.097 91.685  1.00 119.27 ? 98  TYR C CE1 1 
ATOM   9990  C CE2 . TYR C 1 98  ? 94.818  186.747 92.844  1.00 119.27 ? 98  TYR C CE2 1 
ATOM   9991  C CZ  . TYR C 1 98  ? 93.627  187.499 92.868  1.00 119.24 ? 98  TYR C CZ  1 
ATOM   9992  O OH  . TYR C 1 98  ? 92.920  187.632 94.019  1.00 119.59 ? 98  TYR C OH  1 
ATOM   9993  N N   . LEU C 1 99  ? 98.647  188.435 89.800  1.00 118.21 ? 99  LEU C N   1 
ATOM   9994  C CA  . LEU C 1 99  ? 99.698  188.950 90.682  1.00 118.72 ? 99  LEU C CA  1 
ATOM   9995  C C   . LEU C 1 99  ? 100.004 190.427 90.395  1.00 118.30 ? 99  LEU C C   1 
ATOM   9996  O O   . LEU C 1 99  ? 99.981  191.255 91.306  1.00 117.34 ? 99  LEU C O   1 
ATOM   9997  C CB  . LEU C 1 99  ? 100.974 188.110 90.495  1.00 118.65 ? 99  LEU C CB  1 
ATOM   9998  C CG  . LEU C 1 99  ? 100.928 186.700 91.106  1.00 118.03 ? 99  LEU C CG  1 
ATOM   9999  C CD1 . LEU C 1 99  ? 102.169 185.932 90.653  1.00 116.65 ? 99  LEU C CD1 1 
ATOM   10000 C CD2 . LEU C 1 99  ? 100.912 186.713 92.632  1.00 117.05 ? 99  LEU C CD2 1 
ATOM   10001 N N   . ARG C 1 100 ? 100.265 190.768 89.129  1.00 119.31 ? 100 ARG C N   1 
ATOM   10002 C CA  . ARG C 1 100 ? 100.729 192.106 88.723  1.00 119.54 ? 100 ARG C CA  1 
ATOM   10003 C C   . ARG C 1 100 ? 99.608  193.152 88.677  1.00 119.57 ? 100 ARG C C   1 
ATOM   10004 O O   . ARG C 1 100 ? 99.879  194.331 88.893  1.00 118.82 ? 100 ARG C O   1 
ATOM   10005 C CB  . ARG C 1 100 ? 101.500 191.956 87.398  1.00 119.18 ? 100 ARG C CB  1 
ATOM   10006 C CG  . ARG C 1 100 ? 102.410 193.147 87.072  1.00 118.90 ? 100 ARG C CG  1 
ATOM   10007 C CD  . ARG C 1 100 ? 103.477 192.774 86.034  1.00 118.50 ? 100 ARG C CD  1 
ATOM   10008 N NE  . ARG C 1 100 ? 102.897 192.378 84.742  1.00 119.54 ? 100 ARG C NE  1 
ATOM   10009 C CZ  . ARG C 1 100 ? 103.548 191.907 83.695  1.00 119.45 ? 100 ARG C CZ  1 
ATOM   10010 N NH1 . ARG C 1 100 ? 102.913 191.652 82.591  1.00 118.72 ? 100 ARG C NH1 1 
ATOM   10011 N NH2 . ARG C 1 100 ? 104.827 191.671 83.711  1.00 118.79 ? 100 ARG C NH2 1 
ATOM   10012 N N   . TRP C 1 101 ? 98.351  192.745 88.476  1.00 122.09 ? 101 TRP C N   1 
ATOM   10013 C CA  . TRP C 1 101 ? 97.185  193.629 88.598  1.00 122.35 ? 101 TRP C CA  1 
ATOM   10014 C C   . TRP C 1 101 ? 96.737  193.868 90.049  1.00 122.56 ? 101 TRP C C   1 
ATOM   10015 O O   . TRP C 1 101 ? 96.193  194.932 90.350  1.00 122.61 ? 101 TRP C O   1 
ATOM   10016 C CB  . TRP C 1 101 ? 96.029  193.041 87.798  1.00 121.13 ? 101 TRP C CB  1 
ATOM   10017 N N   . ASN C 1 102 ? 96.970  192.918 90.965  1.00 121.10 ? 102 ASN C N   1 
ATOM   10018 C CA  . ASN C 1 102 ? 96.629  193.046 92.389  1.00 120.92 ? 102 ASN C CA  1 
ATOM   10019 C C   . ASN C 1 102 ? 97.832  193.436 93.283  1.00 121.31 ? 102 ASN C C   1 
ATOM   10020 O O   . ASN C 1 102 ? 97.701  193.463 94.504  1.00 120.65 ? 102 ASN C O   1 
ATOM   10021 C CB  . ASN C 1 102 ? 95.928  191.748 92.843  1.00 121.43 ? 102 ASN C CB  1 
ATOM   10022 C CG  . ASN C 1 102 ? 95.026  191.908 94.060  1.00 121.61 ? 102 ASN C CG  1 
ATOM   10023 O OD1 . ASN C 1 102 ? 95.087  191.152 95.017  1.00 121.74 ? 102 ASN C OD1 1 
ATOM   10024 N ND2 . ASN C 1 102 ? 94.142  192.873 94.069  1.00 120.82 ? 102 ASN C ND2 1 
ATOM   10025 N N   . SER C 1 103 ? 98.989  193.751 92.687  1.00 120.75 ? 103 SER C N   1 
ATOM   10026 C CA  . SER C 1 103 ? 100.227 194.181 93.366  1.00 120.64 ? 103 SER C CA  1 
ATOM   10027 C C   . SER C 1 103 ? 100.748 193.186 94.416  1.00 120.86 ? 103 SER C C   1 
ATOM   10028 O O   . SER C 1 103 ? 101.040 193.557 95.557  1.00 119.69 ? 103 SER C O   1 
ATOM   10029 C CB  . SER C 1 103 ? 100.095 195.611 93.916  1.00 120.25 ? 103 SER C CB  1 
ATOM   10030 O OG  . SER C 1 103 ? 99.769  196.512 92.875  1.00 120.01 ? 103 SER C OG  1 
ATOM   10031 N N   . LYS C 1 104 ? 100.846 191.906 94.030  1.00 118.71 ? 104 LYS C N   1 
ATOM   10032 C CA  . LYS C 1 104 ? 101.238 190.764 94.879  1.00 118.04 ? 104 LYS C CA  1 
ATOM   10033 C C   . LYS C 1 104 ? 102.323 189.905 94.228  1.00 118.00 ? 104 LYS C C   1 
ATOM   10034 O O   . LYS C 1 104 ? 102.508 189.947 93.014  1.00 117.40 ? 104 LYS C O   1 
ATOM   10035 C CB  . LYS C 1 104 ? 100.005 189.908 95.210  1.00 117.33 ? 104 LYS C CB  1 
ATOM   10036 C CG  . LYS C 1 104 ? 99.162  190.554 96.313  1.00 117.46 ? 104 LYS C CG  1 
ATOM   10037 C CD  . LYS C 1 104 ? 97.864  189.786 96.555  1.00 118.29 ? 104 LYS C CD  1 
ATOM   10038 C CE  . LYS C 1 104 ? 97.050  190.508 97.634  1.00 118.23 ? 104 LYS C CE  1 
ATOM   10039 N NZ  . LYS C 1 104 ? 95.645  190.052 97.658  1.00 116.88 ? 104 LYS C NZ  1 
ATOM   10040 N N   . TYR C 1 105 ? 103.021 189.108 95.032  1.00 113.16 ? 105 TYR C N   1 
ATOM   10041 C CA  . TYR C 1 105 ? 104.148 188.265 94.613  1.00 112.44 ? 105 TYR C CA  1 
ATOM   10042 C C   . TYR C 1 105 ? 104.080 186.855 95.220  1.00 111.33 ? 105 TYR C C   1 
ATOM   10043 O O   . TYR C 1 105 ? 103.522 186.652 96.297  1.00 110.97 ? 105 TYR C O   1 
ATOM   10044 C CB  . TYR C 1 105 ? 105.473 188.929 95.012  1.00 111.65 ? 105 TYR C CB  1 
ATOM   10045 C CG  . TYR C 1 105 ? 105.573 190.422 94.774  1.00 112.52 ? 105 TYR C CG  1 
ATOM   10046 C CD1 . TYR C 1 105 ? 105.608 190.931 93.463  1.00 112.11 ? 105 TYR C CD1 1 
ATOM   10047 C CD2 . TYR C 1 105 ? 105.626 191.306 95.866  1.00 111.75 ? 105 TYR C CD2 1 
ATOM   10048 C CE1 . TYR C 1 105 ? 105.706 192.317 93.251  1.00 111.96 ? 105 TYR C CE1 1 
ATOM   10049 C CE2 . TYR C 1 105 ? 105.731 192.691 95.656  1.00 112.68 ? 105 TYR C CE2 1 
ATOM   10050 C CZ  . TYR C 1 105 ? 105.768 193.201 94.342  1.00 112.53 ? 105 TYR C CZ  1 
ATOM   10051 O OH  . TYR C 1 105 ? 105.851 194.537 94.126  1.00 111.09 ? 105 TYR C OH  1 
ATOM   10052 N N   . LEU C 1 106 ? 104.723 185.873 94.584  1.00 104.46 ? 106 LEU C N   1 
ATOM   10053 C CA  . LEU C 1 106 ? 104.774 184.489 95.078  1.00 103.94 ? 106 LEU C CA  1 
ATOM   10054 C C   . LEU C 1 106 ? 105.524 184.321 96.417  1.00 104.37 ? 106 LEU C C   1 
ATOM   10055 O O   . LEU C 1 106 ? 105.334 183.318 97.099  1.00 104.37 ? 106 LEU C O   1 
ATOM   10056 C CB  . LEU C 1 106 ? 105.381 183.596 93.985  1.00 103.68 ? 106 LEU C CB  1 
ATOM   10057 C CG  . LEU C 1 106 ? 104.532 183.499 92.706  1.00 103.78 ? 106 LEU C CG  1 
ATOM   10058 C CD1 . LEU C 1 106 ? 105.232 182.642 91.656  1.00 103.65 ? 106 LEU C CD1 1 
ATOM   10059 C CD2 . LEU C 1 106 ? 103.166 182.885 93.001  1.00 104.92 ? 106 LEU C CD2 1 
ATOM   10060 N N   . THR C 1 107 ? 106.343 185.298 96.823  1.00 106.89 ? 107 THR C N   1 
ATOM   10061 C CA  . THR C 1 107 ? 106.994 185.348 98.148  1.00 106.88 ? 107 THR C CA  1 
ATOM   10062 C C   . THR C 1 107 ? 106.049 185.836 99.261  1.00 106.69 ? 107 THR C C   1 
ATOM   10063 O O   . THR C 1 107 ? 106.352 185.673 100.443 1.00 106.20 ? 107 THR C O   1 
ATOM   10064 C CB  . THR C 1 107 ? 108.268 186.219 98.092  1.00 107.43 ? 107 THR C CB  1 
ATOM   10065 O OG1 . THR C 1 107 ? 109.144 185.714 97.115  1.00 107.14 ? 107 THR C OG1 1 
ATOM   10066 C CG2 . THR C 1 107 ? 109.095 186.250 99.374  1.00 106.27 ? 107 THR C CG2 1 
ATOM   10067 N N   . ASP C 1 108 ? 104.899 186.432 98.931  1.00 110.99 ? 108 ASP C N   1 
ATOM   10068 C CA  . ASP C 1 108 ? 103.938 186.935 99.929  1.00 110.82 ? 108 ASP C CA  1 
ATOM   10069 C C   . ASP C 1 108 ? 103.268 185.796 100.710 1.00 110.07 ? 108 ASP C C   1 
ATOM   10070 O O   . ASP C 1 108 ? 102.982 184.735 100.156 1.00 110.29 ? 108 ASP C O   1 
ATOM   10071 C CB  . ASP C 1 108 ? 102.850 187.805 99.279  1.00 110.68 ? 108 ASP C CB  1 
ATOM   10072 C CG  . ASP C 1 108 ? 103.367 189.081 98.605  1.00 110.92 ? 108 ASP C CG  1 
ATOM   10073 O OD1 . ASP C 1 108 ? 104.464 189.556 98.965  1.00 110.70 ? 108 ASP C OD1 1 
ATOM   10074 O OD2 . ASP C 1 108 ? 102.629 189.645 97.772  1.00 111.02 ? 108 ASP C OD2 1 
ATOM   10075 N N   . SER C 1 109 ? 102.950 186.037 101.986 1.00 107.64 ? 109 SER C N   1 
ATOM   10076 C CA  . SER C 1 109 ? 102.426 185.021 102.919 1.00 108.90 ? 109 SER C CA  1 
ATOM   10077 C C   . SER C 1 109 ? 101.226 184.236 102.370 1.00 108.21 ? 109 SER C C   1 
ATOM   10078 O O   . SER C 1 109 ? 101.163 183.015 102.529 1.00 107.47 ? 109 SER C O   1 
ATOM   10079 C CB  . SER C 1 109 ? 102.063 185.700 104.246 1.00 107.50 ? 109 SER C CB  1 
ATOM   10080 O OG  . SER C 1 109 ? 101.596 184.757 105.188 1.00 106.76 ? 109 SER C OG  1 
ATOM   10081 N N   . ALA C 1 110 ? 100.329 184.898 101.635 1.00 110.05 ? 110 ALA C N   1 
ATOM   10082 C CA  . ALA C 1 110 ? 99.160  184.285 101.005 1.00 109.78 ? 110 ALA C CA  1 
ATOM   10083 C C   . ALA C 1 110 ? 99.482  183.091 100.082 1.00 110.38 ? 110 ALA C C   1 
ATOM   10084 O O   . ALA C 1 110 ? 98.682  182.162 100.000 1.00 110.68 ? 110 ALA C O   1 
ATOM   10085 C CB  . ALA C 1 110 ? 98.429  185.381 100.226 1.00 108.63 ? 110 ALA C CB  1 
ATOM   10086 N N   . TYR C 1 111 ? 100.651 183.080 99.427  1.00 107.69 ? 111 TYR C N   1 
ATOM   10087 C CA  . TYR C 1 111 ? 101.104 182.003 98.535  1.00 107.38 ? 111 TYR C CA  1 
ATOM   10088 C C   . TYR C 1 111 ? 102.038 180.985 99.225  1.00 106.70 ? 111 TYR C C   1 
ATOM   10089 O O   . TYR C 1 111 ? 102.744 180.232 98.555  1.00 106.91 ? 111 TYR C O   1 
ATOM   10090 C CB  . TYR C 1 111 ? 101.689 182.607 97.248  1.00 107.86 ? 111 TYR C CB  1 
ATOM   10091 C CG  . TYR C 1 111 ? 100.659 183.291 96.366  1.00 108.31 ? 111 TYR C CG  1 
ATOM   10092 C CD1 . TYR C 1 111 ? 99.824  182.513 95.539  1.00 107.74 ? 111 TYR C CD1 1 
ATOM   10093 C CD2 . TYR C 1 111 ? 100.528 184.690 96.369  1.00 109.10 ? 111 TYR C CD2 1 
ATOM   10094 C CE1 . TYR C 1 111 ? 98.862  183.127 94.716  1.00 108.56 ? 111 TYR C CE1 1 
ATOM   10095 C CE2 . TYR C 1 111 ? 99.550  185.307 95.564  1.00 108.60 ? 111 TYR C CE2 1 
ATOM   10096 C CZ  . TYR C 1 111 ? 98.714  184.528 94.737  1.00 109.01 ? 111 TYR C CZ  1 
ATOM   10097 O OH  . TYR C 1 111 ? 97.762  185.132 93.979  1.00 109.27 ? 111 TYR C OH  1 
ATOM   10098 N N   . THR C 1 112 ? 102.030 180.911 100.561 1.00 98.27  ? 112 THR C N   1 
ATOM   10099 C CA  . THR C 1 112 ? 102.875 180.002 101.360 1.00 98.01  ? 112 THR C CA  1 
ATOM   10100 C C   . THR C 1 112 ? 102.063 179.001 102.187 1.00 97.99  ? 112 THR C C   1 
ATOM   10101 O O   . THR C 1 112 ? 100.917 179.272 102.530 1.00 99.37  ? 112 THR C O   1 
ATOM   10102 C CB  . THR C 1 112 ? 103.834 180.767 102.282 1.00 97.28  ? 112 THR C CB  1 
ATOM   10103 O OG1 . THR C 1 112 ? 103.162 181.342 103.377 1.00 97.07  ? 112 THR C OG1 1 
ATOM   10104 C CG2 . THR C 1 112 ? 104.618 181.867 101.577 1.00 96.67  ? 112 THR C CG2 1 
ATOM   10105 N N   . GLU C 1 113 ? 102.655 177.861 102.571 1.00 91.89  ? 113 GLU C N   1 
ATOM   10106 C CA  . GLU C 1 113 ? 101.989 176.856 103.430 1.00 91.95  ? 113 GLU C CA  1 
ATOM   10107 C C   . GLU C 1 113 ? 101.607 177.377 104.835 1.00 91.71  ? 113 GLU C C   1 
ATOM   10108 O O   . GLU C 1 113 ? 100.861 176.716 105.556 1.00 92.32  ? 113 GLU C O   1 
ATOM   10109 C CB  . GLU C 1 113 ? 102.830 175.567 103.550 1.00 90.83  ? 113 GLU C CB  1 
ATOM   10110 C CG  . GLU C 1 113 ? 103.065 174.858 102.206 1.00 92.23  ? 113 GLU C CG  1 
ATOM   10111 C CD  . GLU C 1 113 ? 102.871 173.333 102.265 1.00 93.31  ? 113 GLU C CD  1 
ATOM   10112 O OE1 . GLU C 1 113 ? 103.672 172.629 102.918 1.00 92.52  ? 113 GLU C OE1 1 
ATOM   10113 O OE2 . GLU C 1 113 ? 101.942 172.820 101.599 1.00 93.27  ? 113 GLU C OE2 1 
ATOM   10114 N N   . GLY C 1 114 ? 102.076 178.566 105.228 1.00 85.24  ? 114 GLY C N   1 
ATOM   10115 C CA  . GLY C 1 114 ? 101.591 179.324 106.390 1.00 86.53  ? 114 GLY C CA  1 
ATOM   10116 C C   . GLY C 1 114 ? 102.098 178.853 107.754 1.00 84.79  ? 114 GLY C C   1 
ATOM   10117 O O   . GLY C 1 114 ? 102.520 179.672 108.570 1.00 82.57  ? 114 GLY C O   1 
ATOM   10118 N N   . SER C 1 115 ? 102.125 177.543 107.998 1.00 82.00  ? 115 SER C N   1 
ATOM   10119 C CA  . SER C 1 115 ? 102.715 176.946 109.204 1.00 82.72  ? 115 SER C CA  1 
ATOM   10120 C C   . SER C 1 115 ? 104.240 177.103 109.257 1.00 84.08  ? 115 SER C C   1 
ATOM   10121 O O   . SER C 1 115 ? 104.809 177.240 110.339 1.00 80.97  ? 115 SER C O   1 
ATOM   10122 C CB  . SER C 1 115 ? 102.326 175.465 109.280 1.00 80.42  ? 115 SER C CB  1 
ATOM   10123 O OG  . SER C 1 115 ? 102.728 174.765 108.117 1.00 80.27  ? 115 SER C OG  1 
ATOM   10124 N N   . THR C 1 116 ? 104.897 177.132 108.092 1.00 79.80  ? 116 THR C N   1 
ATOM   10125 C CA  . THR C 1 116 ? 106.362 177.225 107.942 1.00 77.34  ? 116 THR C CA  1 
ATOM   10126 C C   . THR C 1 116 ? 106.837 178.375 107.050 1.00 75.68  ? 116 THR C C   1 
ATOM   10127 O O   . THR C 1 116 ? 108.020 178.693 107.046 1.00 77.45  ? 116 THR C O   1 
ATOM   10128 C CB  . THR C 1 116 ? 106.921 175.913 107.372 1.00 76.51  ? 116 THR C CB  1 
ATOM   10129 O OG1 . THR C 1 116 ? 106.355 175.699 106.097 1.00 76.06  ? 116 THR C OG1 1 
ATOM   10130 C CG2 . THR C 1 116 ? 106.589 174.678 108.205 1.00 76.21  ? 116 THR C CG2 1 
ATOM   10131 N N   . GLY C 1 117 ? 105.967 179.025 106.267 1.00 77.21  ? 117 GLY C N   1 
ATOM   10132 C CA  . GLY C 1 117 ? 106.431 180.040 105.297 1.00 77.79  ? 117 GLY C CA  1 
ATOM   10133 C C   . GLY C 1 117 ? 107.069 179.368 104.089 1.00 77.65  ? 117 GLY C C   1 
ATOM   10134 O O   . GLY C 1 117 ? 107.976 179.980 103.491 1.00 78.08  ? 117 GLY C O   1 
ATOM   10135 N N   . LYS C 1 118 ? 106.618 178.157 103.742 1.00 78.99  ? 118 LYS C N   1 
ATOM   10136 C CA  . LYS C 1 118 ? 107.184 177.382 102.598 1.00 78.36  ? 118 LYS C CA  1 
ATOM   10137 C C   . LYS C 1 118 ? 106.464 177.796 101.320 1.00 78.60  ? 118 LYS C C   1 
ATOM   10138 O O   . LYS C 1 118 ? 105.235 177.972 101.403 1.00 82.27  ? 118 LYS C O   1 
ATOM   10139 C CB  . LYS C 1 118 ? 107.019 175.909 102.928 1.00 78.39  ? 118 LYS C CB  1 
ATOM   10140 C CG  . LYS C 1 118 ? 107.147 174.880 101.801 1.00 79.70  ? 118 LYS C CG  1 
ATOM   10141 C CD  . LYS C 1 118 ? 106.723 173.488 102.212 1.00 80.69  ? 118 LYS C CD  1 
ATOM   10142 C CE  . LYS C 1 118 ? 106.649 172.524 101.047 1.00 80.63  ? 118 LYS C CE  1 
ATOM   10143 N NZ  . LYS C 1 118 ? 106.162 171.190 101.473 1.00 81.28  ? 118 LYS C NZ  1 
ATOM   10144 N N   . THR C 1 119 ? 107.146 177.948 100.185 1.00 80.46  ? 119 THR C N   1 
ATOM   10145 C CA  . THR C 1 119 ? 106.601 178.556 98.951  1.00 80.65  ? 119 THR C CA  1 
ATOM   10146 C C   . THR C 1 119 ? 106.232 177.543 97.860  1.00 79.21  ? 119 THR C C   1 
ATOM   10147 O O   . THR C 1 119 ? 106.583 176.363 97.929  1.00 77.95  ? 119 THR C O   1 
ATOM   10148 C CB  . THR C 1 119 ? 107.595 179.585 98.374  1.00 82.00  ? 119 THR C CB  1 
ATOM   10149 O OG1 . THR C 1 119 ? 108.749 178.938 97.884  1.00 80.18  ? 119 THR C OG1 1 
ATOM   10150 C CG2 . THR C 1 119 ? 108.039 180.630 99.390  1.00 80.48  ? 119 THR C CG2 1 
ATOM   10151 N N   . CYS C 1 120 ? 105.572 178.010 96.799  1.00 85.58  ? 120 CYS C N   1 
ATOM   10152 C CA  . CYS C 1 120 ? 105.262 177.225 95.604  1.00 87.13  ? 120 CYS C CA  1 
ATOM   10153 C C   . CYS C 1 120 ? 106.517 176.663 94.922  1.00 84.99  ? 120 CYS C C   1 
ATOM   10154 O O   . CYS C 1 120 ? 106.490 175.524 94.475  1.00 83.99  ? 120 CYS C O   1 
ATOM   10155 C CB  . CYS C 1 120 ? 104.455 178.111 94.643  1.00 86.44  ? 120 CYS C CB  1 
ATOM   10156 S SG  . CYS C 1 120 ? 105.362 179.639 94.302  1.00 87.55  ? 120 CYS C SG  1 
ATOM   10157 N N   . LEU C 1 121 ? 107.635 177.401 94.900  1.00 80.77  ? 121 LEU C N   1 
ATOM   10158 C CA  . LEU C 1 121 ? 108.911 176.909 94.363  1.00 80.01  ? 121 LEU C CA  1 
ATOM   10159 C C   . LEU C 1 121 ? 109.466 175.746 95.190  1.00 78.17  ? 121 LEU C C   1 
ATOM   10160 O O   . LEU C 1 121 ? 109.872 174.739 94.624  1.00 77.39  ? 121 LEU C O   1 
ATOM   10161 C CB  . LEU C 1 121 ? 109.913 178.070 94.268  1.00 78.46  ? 121 LEU C CB  1 
ATOM   10162 C CG  . LEU C 1 121 ? 111.317 177.653 93.802  1.00 78.65  ? 121 LEU C CG  1 
ATOM   10163 C CD1 . LEU C 1 121 ? 111.312 177.125 92.375  1.00 78.23  ? 121 LEU C CD1 1 
ATOM   10164 C CD2 . LEU C 1 121 ? 112.247 178.854 93.855  1.00 78.05  ? 121 LEU C CD2 1 
ATOM   10165 N N   . MET C 1 122 ? 109.425 175.815 96.521  1.00 73.09  ? 122 MET C N   1 
ATOM   10166 C CA  . MET C 1 122 ? 109.798 174.668 97.355  1.00 73.38  ? 122 MET C CA  1 
ATOM   10167 C C   . MET C 1 122 ? 108.897 173.464 97.072  1.00 75.13  ? 122 MET C C   1 
ATOM   10168 O O   . MET C 1 122 ? 109.387 172.347 96.912  1.00 72.75  ? 122 MET C O   1 
ATOM   10169 C CB  . MET C 1 122 ? 109.717 175.031 98.836  1.00 72.11  ? 122 MET C CB  1 
ATOM   10170 C CG  . MET C 1 122 ? 110.687 176.140 99.220  1.00 70.76  ? 122 MET C CG  1 
ATOM   10171 S SD  . MET C 1 122 ? 110.558 176.578 100.961 1.00 76.71  ? 122 MET C SD  1 
ATOM   10172 C CE  . MET C 1 122 ? 111.262 178.232 100.907 1.00 71.77  ? 122 MET C CE  1 
ATOM   10173 N N   . LYS C 1 123 ? 107.584 173.687 96.937  1.00 82.09  ? 123 LYS C N   1 
ATOM   10174 C CA  . LYS C 1 123 ? 106.630 172.623 96.592  1.00 80.91  ? 123 LYS C CA  1 
ATOM   10175 C C   . LYS C 1 123 ? 106.784 172.099 95.151  1.00 79.18  ? 123 LYS C C   1 
ATOM   10176 O O   . LYS C 1 123 ? 106.404 170.964 94.896  1.00 79.42  ? 123 LYS C O   1 
ATOM   10177 C CB  . LYS C 1 123 ? 105.206 173.094 96.940  1.00 81.91  ? 123 LYS C CB  1 
ATOM   10178 C CG  . LYS C 1 123 ? 104.276 171.915 97.249  1.00 82.47  ? 123 LYS C CG  1 
ATOM   10179 C CD  . LYS C 1 123 ? 103.016 172.342 98.007  1.00 82.52  ? 123 LYS C CD  1 
ATOM   10180 C CE  . LYS C 1 123 ? 102.224 171.101 98.433  1.00 82.96  ? 123 LYS C CE  1 
ATOM   10181 N NZ  . LYS C 1 123 ? 101.128 171.410 99.382  1.00 83.82  ? 123 LYS C NZ  1 
ATOM   10182 N N   . ALA C 1 124 ? 107.375 172.875 94.243  1.00 79.04  ? 124 ALA C N   1 
ATOM   10183 C CA  . ALA C 1 124 ? 107.780 172.450 92.899  1.00 79.68  ? 124 ALA C CA  1 
ATOM   10184 C C   . ALA C 1 124 ? 109.071 171.604 92.906  1.00 79.53  ? 124 ALA C C   1 
ATOM   10185 O O   . ALA C 1 124 ? 109.201 170.667 92.122  1.00 80.54  ? 124 ALA C O   1 
ATOM   10186 C CB  . ALA C 1 124 ? 107.987 173.697 92.030  1.00 78.54  ? 124 ALA C CB  1 
ATOM   10187 N N   . VAL C 1 125 ? 110.041 171.944 93.764  1.00 74.40  ? 125 VAL C N   1 
ATOM   10188 C CA  . VAL C 1 125 ? 111.305 171.204 93.917  1.00 72.94  ? 125 VAL C CA  1 
ATOM   10189 C C   . VAL C 1 125 ? 111.093 169.876 94.662  1.00 73.58  ? 125 VAL C C   1 
ATOM   10190 O O   . VAL C 1 125 ? 111.790 168.899 94.404  1.00 73.37  ? 125 VAL C O   1 
ATOM   10191 C CB  . VAL C 1 125 ? 112.363 172.095 94.598  1.00 70.50  ? 125 VAL C CB  1 
ATOM   10192 C CG1 . VAL C 1 125 ? 113.665 171.355 94.875  1.00 69.26  ? 125 VAL C CG1 1 
ATOM   10193 C CG2 . VAL C 1 125 ? 112.740 173.286 93.711  1.00 71.38  ? 125 VAL C CG2 1 
ATOM   10194 N N   . LEU C 1 126 ? 110.098 169.784 95.545  1.00 71.90  ? 126 LEU C N   1 
ATOM   10195 C CA  . LEU C 1 126 ? 109.576 168.495 96.017  1.00 71.31  ? 126 LEU C CA  1 
ATOM   10196 C C   . LEU C 1 126 ? 108.851 167.739 94.883  1.00 74.39  ? 126 LEU C C   1 
ATOM   10197 O O   . LEU C 1 126 ? 108.240 168.339 94.008  1.00 77.05  ? 126 LEU C O   1 
ATOM   10198 C CB  . LEU C 1 126 ? 108.662 168.732 97.228  1.00 71.57  ? 126 LEU C CB  1 
ATOM   10199 C CG  . LEU C 1 126 ? 109.407 169.307 98.446  1.00 69.04  ? 126 LEU C CG  1 
ATOM   10200 C CD1 . LEU C 1 126 ? 108.424 169.817 99.487  1.00 67.47  ? 126 LEU C CD1 1 
ATOM   10201 C CD2 . LEU C 1 126 ? 110.301 168.257 99.092  1.00 68.13  ? 126 LEU C CD2 1 
ATOM   10202 N N   . ASN C 1 127 ? 108.915 166.401 94.897  1.00 81.78  ? 127 ASN C N   1 
ATOM   10203 C CA  . ASN C 1 127 ? 108.270 165.556 93.849  1.00 84.68  ? 127 ASN C CA  1 
ATOM   10204 C C   . ASN C 1 127 ? 108.785 165.961 92.460  1.00 83.67  ? 127 ASN C C   1 
ATOM   10205 O O   . ASN C 1 127 ? 108.040 166.639 91.725  1.00 81.53  ? 127 ASN C O   1 
ATOM   10206 C CB  . ASN C 1 127 ? 106.737 165.514 93.967  1.00 84.29  ? 127 ASN C CB  1 
ATOM   10207 C CG  . ASN C 1 127 ? 106.051 166.863 93.900  1.00 84.06  ? 127 ASN C CG  1 
ATOM   10208 O OD1 . ASN C 1 127 ? 105.679 167.325 92.824  1.00 84.79  ? 127 ASN C OD1 1 
ATOM   10209 N ND2 . ASN C 1 127 ? 105.866 167.495 95.047  1.00 82.51  ? 127 ASN C ND2 1 
ATOM   10210 N N   . LEU C 1 128 ? 110.013 165.555 92.119  1.00 88.67  ? 128 LEU C N   1 
ATOM   10211 C CA  . LEU C 1 128 ? 110.565 165.834 90.764  1.00 86.50  ? 128 LEU C CA  1 
ATOM   10212 C C   . LEU C 1 128 ? 110.417 164.571 89.911  1.00 88.71  ? 128 LEU C C   1 
ATOM   10213 O O   . LEU C 1 128 ? 110.714 163.476 90.428  1.00 88.00  ? 128 LEU C O   1 
ATOM   10214 C CB  . LEU C 1 128 ? 112.036 166.240 90.890  1.00 88.40  ? 128 LEU C CB  1 
ATOM   10215 C CG  . LEU C 1 128 ? 112.297 167.533 91.660  1.00 87.99  ? 128 LEU C CG  1 
ATOM   10216 C CD1 . LEU C 1 128 ? 113.784 167.851 91.696  1.00 86.78  ? 128 LEU C CD1 1 
ATOM   10217 C CD2 . LEU C 1 128 ? 111.522 168.690 91.049  1.00 86.79  ? 128 LEU C CD2 1 
ATOM   10218 N N   . GLN C 1 129 ? 109.978 164.718 88.658  1.00 99.13  ? 129 GLN C N   1 
ATOM   10219 C CA  . GLN C 1 129 ? 109.752 163.556 87.792  1.00 98.53  ? 129 GLN C CA  1 
ATOM   10220 C C   . GLN C 1 129 ? 111.007 163.285 86.951  1.00 98.99  ? 129 GLN C C   1 
ATOM   10221 O O   . GLN C 1 129 ? 111.504 164.180 86.269  1.00 99.43  ? 129 GLN C O   1 
ATOM   10222 C CB  . GLN C 1 129 ? 108.524 163.804 86.899  1.00 98.10  ? 129 GLN C CB  1 
ATOM   10223 C CG  . GLN C 1 129 ? 107.238 164.073 87.700  1.00 97.97  ? 129 GLN C CG  1 
ATOM   10224 C CD  . GLN C 1 129 ? 105.989 164.205 86.831  1.00 100.35 ? 129 GLN C CD  1 
ATOM   10225 O OE1 . GLN C 1 129 ? 106.012 164.138 85.610  1.00 99.99  ? 129 GLN C OE1 1 
ATOM   10226 N NE2 . GLN C 1 129 ? 104.837 164.395 87.430  1.00 99.45  ? 129 GLN C NE2 1 
ATOM   10227 N N   . ASP C 1 130 ? 111.590 162.085 87.024  1.00 98.50  ? 130 ASP C N   1 
ATOM   10228 C CA  . ASP C 1 130 ? 112.865 161.761 86.359  1.00 99.35  ? 130 ASP C CA  1 
ATOM   10229 C C   . ASP C 1 130 ? 114.019 162.749 86.651  1.00 98.79  ? 130 ASP C C   1 
ATOM   10230 O O   . ASP C 1 130 ? 114.902 162.971 85.819  1.00 98.45  ? 130 ASP C O   1 
ATOM   10231 C CB  . ASP C 1 130 ? 112.626 161.567 84.862  1.00 98.90  ? 130 ASP C CB  1 
ATOM   10232 N N   . GLY C 1 131 ? 114.004 163.376 87.833  1.00 92.19  ? 131 GLY C N   1 
ATOM   10233 C CA  . GLY C 1 131 ? 114.991 164.360 88.280  1.00 92.49  ? 131 GLY C CA  1 
ATOM   10234 C C   . GLY C 1 131 ? 114.719 165.824 87.903  1.00 92.69  ? 131 GLY C C   1 
ATOM   10235 O O   . GLY C 1 131 ? 115.544 166.674 88.230  1.00 92.12  ? 131 GLY C O   1 
ATOM   10236 N N   . VAL C 1 132 ? 113.591 166.155 87.261  1.00 93.37  ? 132 VAL C N   1 
ATOM   10237 C CA  . VAL C 1 132 ? 113.252 167.530 86.831  1.00 94.39  ? 132 VAL C CA  1 
ATOM   10238 C C   . VAL C 1 132 ? 111.764 167.868 87.037  1.00 93.30  ? 132 VAL C C   1 
ATOM   10239 O O   . VAL C 1 132 ? 110.928 166.989 87.216  1.00 92.56  ? 132 VAL C O   1 
ATOM   10240 C CB  . VAL C 1 132 ? 113.738 167.741 85.381  1.00 95.87  ? 132 VAL C CB  1 
ATOM   10241 C CG1 . VAL C 1 132 ? 112.914 166.968 84.352  1.00 94.85  ? 132 VAL C CG1 1 
ATOM   10242 C CG2 . VAL C 1 132 ? 113.791 169.216 84.971  1.00 93.64  ? 132 VAL C CG2 1 
ATOM   10243 N N   . ASN C 1 133 ? 111.416 169.155 87.035  1.00 94.06  ? 133 ASN C N   1 
ATOM   10244 C CA  . ASN C 1 133 ? 110.029 169.621 87.038  1.00 94.69  ? 133 ASN C CA  1 
ATOM   10245 C C   . ASN C 1 133 ? 109.875 170.814 86.080  1.00 94.20  ? 133 ASN C C   1 
ATOM   10246 O O   . ASN C 1 133 ? 110.442 171.887 86.308  1.00 94.08  ? 133 ASN C O   1 
ATOM   10247 C CB  . ASN C 1 133 ? 109.611 169.937 88.485  1.00 94.48  ? 133 ASN C CB  1 
ATOM   10248 C CG  . ASN C 1 133 ? 108.183 170.431 88.622  1.00 93.51  ? 133 ASN C CG  1 
ATOM   10249 O OD1 . ASN C 1 133 ? 107.531 170.825 87.669  1.00 95.02  ? 133 ASN C OD1 1 
ATOM   10250 N ND2 . ASN C 1 133 ? 107.652 170.420 89.812  1.00 92.72  ? 133 ASN C ND2 1 
ATOM   10251 N N   . ALA C 1 134 ? 109.083 170.634 85.023  1.00 96.21  ? 134 ALA C N   1 
ATOM   10252 C CA  . ALA C 1 134 ? 108.864 171.633 83.974  1.00 96.93  ? 134 ALA C CA  1 
ATOM   10253 C C   . ALA C 1 134 ? 108.232 172.949 84.466  1.00 97.70  ? 134 ALA C C   1 
ATOM   10254 O O   . ALA C 1 134 ? 108.326 173.963 83.780  1.00 98.40  ? 134 ALA C O   1 
ATOM   10255 C CB  . ALA C 1 134 ? 107.995 170.987 82.890  1.00 97.40  ? 134 ALA C CB  1 
ATOM   10256 N N   . CYS C 1 135 ? 107.614 172.962 85.649  1.00 97.37  ? 135 CYS C N   1 
ATOM   10257 C CA  . CYS C 1 135 ? 106.999 174.146 86.248  1.00 97.56  ? 135 CYS C CA  1 
ATOM   10258 C C   . CYS C 1 135 ? 108.007 175.130 86.884  1.00 99.00  ? 135 CYS C C   1 
ATOM   10259 O O   . CYS C 1 135 ? 107.706 176.314 87.013  1.00 98.08  ? 135 CYS C O   1 
ATOM   10260 C CB  . CYS C 1 135 ? 105.959 173.637 87.252  1.00 98.69  ? 135 CYS C CB  1 
ATOM   10261 S SG  . CYS C 1 135 ? 104.903 174.982 87.832  1.00 103.17 ? 135 CYS C SG  1 
ATOM   10262 N N   . ILE C 1 136 ? 109.226 174.692 87.242  1.00 96.04  ? 136 ILE C N   1 
ATOM   10263 C CA  . ILE C 1 136 ? 110.182 175.536 87.989  1.00 94.57  ? 136 ILE C CA  1 
ATOM   10264 C C   . ILE C 1 136 ? 110.604 176.782 87.190  1.00 94.76  ? 136 ILE C C   1 
ATOM   10265 O O   . ILE C 1 136 ? 110.523 177.898 87.707  1.00 94.69  ? 136 ILE C O   1 
ATOM   10266 C CB  . ILE C 1 136 ? 111.388 174.703 88.486  1.00 94.45  ? 136 ILE C CB  1 
ATOM   10267 C CG1 . ILE C 1 136 ? 110.920 173.679 89.542  1.00 93.41  ? 136 ILE C CG1 1 
ATOM   10268 C CG2 . ILE C 1 136 ? 112.462 175.614 89.100  1.00 94.90  ? 136 ILE C CG2 1 
ATOM   10269 C CD1 . ILE C 1 136 ? 111.989 172.661 89.954  1.00 92.27  ? 136 ILE C CD1 1 
ATOM   10270 N N   . MET C 1 137 ? 111.011 176.634 85.922  1.00 98.27  ? 137 MET C N   1 
ATOM   10271 C CA  . MET C 1 137 ? 111.346 177.791 85.078  1.00 98.89  ? 137 MET C CA  1 
ATOM   10272 C C   . MET C 1 137 ? 110.163 178.772 84.915  1.00 99.81  ? 137 MET C C   1 
ATOM   10273 O O   . MET C 1 137 ? 110.353 179.946 85.218  1.00 98.91  ? 137 MET C O   1 
ATOM   10274 C CB  . MET C 1 137 ? 111.926 177.362 83.720  1.00 98.90  ? 137 MET C CB  1 
ATOM   10275 C CG  . MET C 1 137 ? 113.360 176.855 83.804  1.00 99.18  ? 137 MET C CG  1 
ATOM   10276 S SD  . MET C 1 137 ? 114.050 176.445 82.180  1.00 103.27 ? 137 MET C SD  1 
ATOM   10277 C CE  . MET C 1 137 ? 115.679 175.823 82.650  1.00 98.88  ? 137 MET C CE  1 
ATOM   10278 N N   . PRO C 1 138 ? 108.941 178.345 84.531  1.00 100.30 ? 138 PRO C N   1 
ATOM   10279 C CA  . PRO C 1 138 ? 107.742 179.183 84.555  1.00 99.91  ? 138 PRO C CA  1 
ATOM   10280 C C   . PRO C 1 138 ? 107.494 179.946 85.861  1.00 100.71 ? 138 PRO C C   1 
ATOM   10281 O O   . PRO C 1 138 ? 107.205 181.140 85.804  1.00 100.65 ? 138 PRO C O   1 
ATOM   10282 C CB  . PRO C 1 138 ? 106.582 178.234 84.259  1.00 101.14 ? 138 PRO C CB  1 
ATOM   10283 C CG  . PRO C 1 138 ? 107.215 177.201 83.342  1.00 100.45 ? 138 PRO C CG  1 
ATOM   10284 C CD  . PRO C 1 138 ? 108.639 177.088 83.868  1.00 99.80  ? 138 PRO C CD  1 
ATOM   10285 N N   . LEU C 1 139 ? 107.647 179.327 87.039  1.00 98.66  ? 139 LEU C N   1 
ATOM   10286 C CA  . LEU C 1 139 ? 107.512 180.034 88.326  1.00 98.69  ? 139 LEU C CA  1 
ATOM   10287 C C   . LEU C 1 139 ? 108.546 181.156 88.477  1.00 99.71  ? 139 LEU C C   1 
ATOM   10288 O O   . LEU C 1 139 ? 108.201 182.271 88.860  1.00 99.21  ? 139 LEU C O   1 
ATOM   10289 C CB  . LEU C 1 139 ? 107.684 179.057 89.501  1.00 99.01  ? 139 LEU C CB  1 
ATOM   10290 C CG  . LEU C 1 139 ? 106.551 178.040 89.677  1.00 99.85  ? 139 LEU C CG  1 
ATOM   10291 C CD1 . LEU C 1 139 ? 107.016 176.958 90.648  1.00 99.03  ? 139 LEU C CD1 1 
ATOM   10292 C CD2 . LEU C 1 139 ? 105.295 178.705 90.248  1.00 100.37 ? 139 LEU C CD2 1 
ATOM   10293 N N   . LEU C 1 140 ? 109.814 180.877 88.162  1.00 98.12  ? 140 LEU C N   1 
ATOM   10294 C CA  . LEU C 1 140 ? 110.899 181.858 88.233  1.00 98.40  ? 140 LEU C CA  1 
ATOM   10295 C C   . LEU C 1 140 ? 110.730 182.974 87.187  1.00 97.90  ? 140 LEU C C   1 
ATOM   10296 O O   . LEU C 1 140 ? 110.994 184.138 87.475  1.00 97.83  ? 140 LEU C O   1 
ATOM   10297 C CB  . LEU C 1 140 ? 112.243 181.124 88.073  1.00 97.32  ? 140 LEU C CB  1 
ATOM   10298 C CG  . LEU C 1 140 ? 112.574 180.157 89.231  1.00 96.23  ? 140 LEU C CG  1 
ATOM   10299 C CD1 . LEU C 1 140 ? 113.732 179.244 88.846  1.00 95.62  ? 140 LEU C CD1 1 
ATOM   10300 C CD2 . LEU C 1 140 ? 112.954 180.916 90.495  1.00 95.66  ? 140 LEU C CD2 1 
ATOM   10301 N N   . GLN C 1 141 ? 110.243 182.651 85.986  1.00 101.73 ? 141 GLN C N   1 
ATOM   10302 C CA  . GLN C 1 141 ? 109.875 183.624 84.960  1.00 102.82 ? 141 GLN C CA  1 
ATOM   10303 C C   . GLN C 1 141 ? 108.741 184.533 85.449  1.00 102.24 ? 141 GLN C C   1 
ATOM   10304 O O   . GLN C 1 141 ? 108.889 185.749 85.420  1.00 102.65 ? 141 GLN C O   1 
ATOM   10305 C CB  . GLN C 1 141 ? 109.482 182.897 83.666  1.00 102.16 ? 141 GLN C CB  1 
ATOM   10306 C CG  . GLN C 1 141 ? 110.695 182.264 82.964  1.00 102.59 ? 141 GLN C CG  1 
ATOM   10307 C CD  . GLN C 1 141 ? 110.325 181.234 81.897  1.00 102.54 ? 141 GLN C CD  1 
ATOM   10308 O OE1 . GLN C 1 141 ? 109.173 180.997 81.561  1.00 101.91 ? 141 GLN C OE1 1 
ATOM   10309 N NE2 . GLN C 1 141 ? 111.301 180.581 81.306  1.00 101.78 ? 141 GLN C NE2 1 
ATOM   10310 N N   . ILE C 1 142 ? 107.646 183.971 85.970  1.00 103.52 ? 142 ILE C N   1 
ATOM   10311 C CA  . ILE C 1 142 ? 106.523 184.743 86.525  1.00 104.66 ? 142 ILE C CA  1 
ATOM   10312 C C   . ILE C 1 142 ? 106.981 185.621 87.698  1.00 104.15 ? 142 ILE C C   1 
ATOM   10313 O O   . ILE C 1 142 ? 106.530 186.756 87.826  1.00 103.82 ? 142 ILE C O   1 
ATOM   10314 C CB  . ILE C 1 142 ? 105.368 183.789 86.914  1.00 104.24 ? 142 ILE C CB  1 
ATOM   10315 C CG1 . ILE C 1 142 ? 104.717 183.233 85.628  1.00 104.41 ? 142 ILE C CG1 1 
ATOM   10316 C CG2 . ILE C 1 142 ? 104.305 184.467 87.792  1.00 103.86 ? 142 ILE C CG2 1 
ATOM   10317 C CD1 . ILE C 1 142 ? 103.763 182.066 85.863  1.00 104.64 ? 142 ILE C CD1 1 
ATOM   10318 N N   . ASP C 1 143 ? 107.884 185.151 88.559  1.00 103.46 ? 143 ASP C N   1 
ATOM   10319 C CA  . ASP C 1 143 ? 108.402 185.957 89.669  1.00 102.99 ? 143 ASP C CA  1 
ATOM   10320 C C   . ASP C 1 143 ? 109.240 187.160 89.188  1.00 103.96 ? 143 ASP C C   1 
ATOM   10321 O O   . ASP C 1 143 ? 109.031 188.288 89.636  1.00 103.29 ? 143 ASP C O   1 
ATOM   10322 C CB  . ASP C 1 143 ? 109.226 185.071 90.608  1.00 102.31 ? 143 ASP C CB  1 
ATOM   10323 C CG  . ASP C 1 143 ? 109.564 185.823 91.897  1.00 103.79 ? 143 ASP C CG  1 
ATOM   10324 O OD1 . ASP C 1 143 ? 108.626 186.337 92.544  1.00 103.82 ? 143 ASP C OD1 1 
ATOM   10325 O OD2 . ASP C 1 143 ? 110.756 185.872 92.265  1.00 103.77 ? 143 ASP C OD2 1 
ATOM   10326 N N   . LYS C 1 144 ? 110.146 186.941 88.224  1.00 105.63 ? 144 LYS C N   1 
ATOM   10327 C CA  . LYS C 1 144 ? 110.940 188.012 87.586  1.00 104.84 ? 144 LYS C CA  1 
ATOM   10328 C C   . LYS C 1 144 ? 110.056 188.994 86.811  1.00 104.99 ? 144 LYS C C   1 
ATOM   10329 O O   . LYS C 1 144 ? 110.211 190.205 86.949  1.00 104.31 ? 144 LYS C O   1 
ATOM   10330 C CB  . LYS C 1 144 ? 112.015 187.392 86.674  1.00 104.36 ? 144 LYS C CB  1 
ATOM   10331 C CG  . LYS C 1 144 ? 113.131 186.712 87.482  1.00 105.16 ? 144 LYS C CG  1 
ATOM   10332 C CD  . LYS C 1 144 ? 114.221 186.055 86.621  1.00 104.04 ? 144 LYS C CD  1 
ATOM   10333 C CE  . LYS C 1 144 ? 113.689 184.925 85.731  1.00 104.11 ? 144 LYS C CE  1 
ATOM   10334 N NZ  . LYS C 1 144 ? 114.789 184.209 85.032  1.00 103.81 ? 144 LYS C NZ  1 
ATOM   10335 N N   . ASP C 1 145 ? 109.075 188.492 86.060  1.00 109.07 ? 145 ASP C N   1 
ATOM   10336 C CA  . ASP C 1 145 ? 108.077 189.298 85.345  1.00 108.90 ? 145 ASP C CA  1 
ATOM   10337 C C   . ASP C 1 145 ? 107.141 190.086 86.281  1.00 108.59 ? 145 ASP C C   1 
ATOM   10338 O O   . ASP C 1 145 ? 106.622 191.133 85.894  1.00 109.56 ? 145 ASP C O   1 
ATOM   10339 C CB  . ASP C 1 145 ? 107.249 188.403 84.407  1.00 108.84 ? 145 ASP C CB  1 
ATOM   10340 C CG  . ASP C 1 145 ? 108.037 187.783 83.240  1.00 108.99 ? 145 ASP C CG  1 
ATOM   10341 O OD1 . ASP C 1 145 ? 109.156 188.256 82.930  1.00 109.19 ? 145 ASP C OD1 1 
ATOM   10342 O OD2 . ASP C 1 145 ? 107.495 186.876 82.569  1.00 107.95 ? 145 ASP C OD2 1 
ATOM   10343 N N   . SER C 1 146 ? 106.943 189.635 87.520  1.00 109.43 ? 146 SER C N   1 
ATOM   10344 C CA  . SER C 1 146 ? 106.180 190.368 88.543  1.00 110.01 ? 146 SER C CA  1 
ATOM   10345 C C   . SER C 1 146 ? 106.957 191.534 89.173  1.00 109.75 ? 146 SER C C   1 
ATOM   10346 O O   . SER C 1 146 ? 106.349 192.378 89.827  1.00 109.08 ? 146 SER C O   1 
ATOM   10347 C CB  . SER C 1 146 ? 105.725 189.422 89.661  1.00 110.34 ? 146 SER C CB  1 
ATOM   10348 O OG  . SER C 1 146 ? 104.923 188.379 89.154  1.00 111.83 ? 146 SER C OG  1 
ATOM   10349 N N   . GLY C 1 147 ? 108.283 191.611 89.008  1.00 107.54 ? 147 GLY C N   1 
ATOM   10350 C CA  . GLY C 1 147 ? 109.110 192.664 89.614  1.00 107.60 ? 147 GLY C CA  1 
ATOM   10351 C C   . GLY C 1 147 ? 109.284 192.543 91.134  1.00 108.39 ? 147 GLY C C   1 
ATOM   10352 O O   . GLY C 1 147 ? 109.423 193.553 91.826  1.00 108.18 ? 147 GLY C O   1 
ATOM   10353 N N   . ASN C 1 148 ? 109.238 191.324 91.677  1.00 107.57 ? 148 ASN C N   1 
ATOM   10354 C CA  . ASN C 1 148 ? 109.288 191.100 93.149  1.00 107.49 ? 148 ASN C CA  1 
ATOM   10355 C C   . ASN C 1 148 ? 110.660 191.479 93.711  1.00 107.05 ? 148 ASN C C   1 
ATOM   10356 O O   . ASN C 1 148 ? 111.670 190.937 93.225  1.00 105.15 ? 148 ASN C O   1 
ATOM   10357 C CB  . ASN C 1 148 ? 108.943 189.649 93.494  1.00 107.11 ? 148 ASN C CB  1 
ATOM   10358 C CG  . ASN C 1 148 ? 109.042 189.334 94.972  1.00 106.35 ? 148 ASN C CG  1 
ATOM   10359 O OD1 . ASN C 1 148 ? 109.069 190.234 95.808  1.00 105.86 ? 148 ASN C OD1 1 
ATOM   10360 N ND2 . ASN C 1 148 ? 109.087 188.054 95.304  1.00 105.53 ? 148 ASN C ND2 1 
ATOM   10361 N N   . PRO C 1 149 ? 110.749 192.379 94.719  1.00 107.28 ? 149 PRO C N   1 
ATOM   10362 C CA  . PRO C 1 149 ? 112.032 192.700 95.347  1.00 107.01 ? 149 PRO C CA  1 
ATOM   10363 C C   . PRO C 1 149 ? 112.604 191.490 96.100  1.00 106.96 ? 149 PRO C C   1 
ATOM   10364 O O   . PRO C 1 149 ? 113.808 191.320 96.080  1.00 106.34 ? 149 PRO C O   1 
ATOM   10365 C CB  . PRO C 1 149 ? 111.693 193.808 96.358  1.00 106.71 ? 149 PRO C CB  1 
ATOM   10366 C CG  . PRO C 1 149 ? 110.369 194.361 95.881  1.00 106.63 ? 149 PRO C CG  1 
ATOM   10367 C CD  . PRO C 1 149 ? 109.650 193.169 95.289  1.00 106.23 ? 149 PRO C CD  1 
ATOM   10368 N N   . LYS C 1 150 ? 111.744 190.687 96.736  1.00 105.24 ? 150 LYS C N   1 
ATOM   10369 C CA  . LYS C 1 150 ? 112.256 189.566 97.545  1.00 103.39 ? 150 LYS C CA  1 
ATOM   10370 C C   . LYS C 1 150 ? 112.120 188.269 96.750  1.00 103.07 ? 150 LYS C C   1 
ATOM   10371 O O   . LYS C 1 150 ? 111.166 187.511 96.937  1.00 103.30 ? 150 LYS C O   1 
ATOM   10372 C CB  . LYS C 1 150 ? 111.509 189.506 98.889  1.00 102.20 ? 150 LYS C CB  1 
ATOM   10373 C CG  . LYS C 1 150 ? 111.801 190.716 99.783  1.00 102.41 ? 150 LYS C CG  1 
ATOM   10374 C CD  . LYS C 1 150 ? 111.021 190.634 101.095 1.00 103.25 ? 150 LYS C CD  1 
ATOM   10375 C CE  . LYS C 1 150 ? 111.329 191.835 101.986 1.00 103.31 ? 150 LYS C CE  1 
ATOM   10376 N NZ  . LYS C 1 150 ? 110.532 191.827 103.223 1.00 103.56 ? 150 LYS C NZ  1 
ATOM   10377 N N   . LEU C 1 151 ? 113.047 188.052 95.816  1.00 96.15  ? 151 LEU C N   1 
ATOM   10378 C CA  . LEU C 1 151 ? 112.950 187.014 94.785  1.00 96.38  ? 151 LEU C CA  1 
ATOM   10379 C C   . LEU C 1 151 ? 112.642 185.624 95.364  1.00 94.37  ? 151 LEU C C   1 
ATOM   10380 O O   . LEU C 1 151 ? 113.239 185.193 96.352  1.00 93.23  ? 151 LEU C O   1 
ATOM   10381 C CB  . LEU C 1 151 ? 114.248 186.970 93.955  1.00 95.56  ? 151 LEU C CB  1 
ATOM   10382 C CG  . LEU C 1 151 ? 114.564 188.239 93.148  1.00 96.59  ? 151 LEU C CG  1 
ATOM   10383 C CD1 . LEU C 1 151 ? 115.950 188.117 92.530  1.00 95.10  ? 151 LEU C CD1 1 
ATOM   10384 C CD2 . LEU C 1 151 ? 113.564 188.471 92.018  1.00 96.82  ? 151 LEU C CD2 1 
ATOM   10385 N N   . LEU C 1 152 ? 111.735 184.901 94.708  1.00 87.55  ? 152 LEU C N   1 
ATOM   10386 C CA  . LEU C 1 152 ? 111.200 183.604 95.132  1.00 87.00  ? 152 LEU C CA  1 
ATOM   10387 C C   . LEU C 1 152 ? 112.290 182.541 95.328  1.00 86.63  ? 152 LEU C C   1 
ATOM   10388 O O   . LEU C 1 152 ? 112.187 181.704 96.219  1.00 86.90  ? 152 LEU C O   1 
ATOM   10389 C CB  . LEU C 1 152 ? 110.178 183.174 94.064  1.00 87.73  ? 152 LEU C CB  1 
ATOM   10390 C CG  . LEU C 1 152 ? 109.518 181.803 94.253  1.00 86.20  ? 152 LEU C CG  1 
ATOM   10391 C CD1 . LEU C 1 152 ? 108.648 181.762 95.503  1.00 86.08  ? 152 LEU C CD1 1 
ATOM   10392 C CD2 . LEU C 1 152 ? 108.663 181.492 93.029  1.00 87.20  ? 152 LEU C CD2 1 
ATOM   10393 N N   . VAL C 1 153 ? 113.363 182.597 94.536  1.00 77.36  ? 153 VAL C N   1 
ATOM   10394 C CA  . VAL C 1 153 ? 114.475 181.636 94.581  1.00 76.09  ? 153 VAL C CA  1 
ATOM   10395 C C   . VAL C 1 153 ? 115.224 181.630 95.927  1.00 74.36  ? 153 VAL C C   1 
ATOM   10396 O O   . VAL C 1 153 ? 115.731 180.594 96.343  1.00 73.12  ? 153 VAL C O   1 
ATOM   10397 C CB  . VAL C 1 153 ? 115.400 181.876 93.373  1.00 73.05  ? 153 VAL C CB  1 
ATOM   10398 C CG1 . VAL C 1 153 ? 116.285 183.113 93.519  1.00 74.16  ? 153 VAL C CG1 1 
ATOM   10399 C CG2 . VAL C 1 153 ? 116.269 180.658 93.082  1.00 71.94  ? 153 VAL C CG2 1 
ATOM   10400 N N   . ASN C 1 154 ? 115.225 182.760 96.643  1.00 72.56  ? 154 ASN C N   1 
ATOM   10401 C CA  . ASN C 1 154 ? 115.876 182.939 97.944  1.00 71.99  ? 154 ASN C CA  1 
ATOM   10402 C C   . ASN C 1 154 ? 114.881 183.048 99.111  1.00 73.30  ? 154 ASN C C   1 
ATOM   10403 O O   . ASN C 1 154 ? 115.274 183.384 100.230 1.00 73.55  ? 154 ASN C O   1 
ATOM   10404 C CB  . ASN C 1 154 ? 116.842 184.136 97.866  1.00 72.62  ? 154 ASN C CB  1 
ATOM   10405 C CG  . ASN C 1 154 ? 117.972 183.870 96.897  1.00 73.60  ? 154 ASN C CG  1 
ATOM   10406 O OD1 . ASN C 1 154 ? 118.468 182.765 96.814  1.00 74.96  ? 154 ASN C OD1 1 
ATOM   10407 N ND2 . ASN C 1 154 ? 118.400 184.831 96.119  1.00 73.67  ? 154 ASN C ND2 1 
ATOM   10408 N N   . ALA C 1 155 ? 113.600 182.764 98.878  1.00 70.02  ? 155 ALA C N   1 
ATOM   10409 C CA  . ALA C 1 155 ? 112.629 182.622 99.956  1.00 67.45  ? 155 ALA C CA  1 
ATOM   10410 C C   . ALA C 1 155 ? 113.012 181.435 100.855 1.00 68.85  ? 155 ALA C C   1 
ATOM   10411 O O   . ALA C 1 155 ? 113.531 180.420 100.386 1.00 67.66  ? 155 ALA C O   1 
ATOM   10412 C CB  . ALA C 1 155 ? 111.224 182.474 99.368  1.00 70.06  ? 155 ALA C CB  1 
ATOM   10413 N N   . GLN C 1 156 ? 112.755 181.566 102.152 1.00 63.39  ? 156 GLN C N   1 
ATOM   10414 C CA  . GLN C 1 156 ? 113.109 180.561 103.153 1.00 59.38  ? 156 GLN C CA  1 
ATOM   10415 C C   . GLN C 1 156 ? 111.944 180.304 104.109 1.00 62.55  ? 156 GLN C C   1 
ATOM   10416 O O   . GLN C 1 156 ? 111.123 181.196 104.331 1.00 65.46  ? 156 GLN C O   1 
ATOM   10417 C CB  . GLN C 1 156 ? 114.349 181.000 103.924 1.00 58.11  ? 156 GLN C CB  1 
ATOM   10418 C CG  . GLN C 1 156 ? 115.645 180.909 103.137 1.00 60.23  ? 156 GLN C CG  1 
ATOM   10419 C CD  . GLN C 1 156 ? 116.770 181.527 103.926 1.00 61.86  ? 156 GLN C CD  1 
ATOM   10420 O OE1 . GLN C 1 156 ? 116.667 182.650 104.411 1.00 60.25  ? 156 GLN C OE1 1 
ATOM   10421 N NE2 . GLN C 1 156 ? 117.852 180.784 104.081 1.00 60.86  ? 156 GLN C NE2 1 
ATOM   10422 N N   . CYS C 1 157 ? 111.896 179.125 104.723 1.00 60.25  ? 157 CYS C N   1 
ATOM   10423 C CA  . CYS C 1 157 ? 111.009 178.846 105.856 1.00 60.53  ? 157 CYS C CA  1 
ATOM   10424 C C   . CYS C 1 157 ? 111.340 179.744 107.069 1.00 63.97  ? 157 CYS C C   1 
ATOM   10425 O O   . CYS C 1 157 ? 112.477 180.195 107.234 1.00 65.44  ? 157 CYS C O   1 
ATOM   10426 C CB  . CYS C 1 157 ? 111.079 177.363 106.218 1.00 59.44  ? 157 CYS C CB  1 
ATOM   10427 S SG  . CYS C 1 157 ? 110.516 176.328 104.841 1.00 66.27  ? 157 CYS C SG  1 
ATOM   10428 N N   . THR C 1 158 ? 110.353 179.991 107.931 1.00 64.48  ? 158 THR C N   1 
ATOM   10429 C CA  . THR C 1 158 ? 110.370 181.078 108.932 1.00 63.84  ? 158 THR C CA  1 
ATOM   10430 C C   . THR C 1 158 ? 110.077 180.605 110.363 1.00 63.94  ? 158 THR C C   1 
ATOM   10431 O O   . THR C 1 158 ? 110.379 181.312 111.320 1.00 64.53  ? 158 THR C O   1 
ATOM   10432 C CB  . THR C 1 158 ? 109.354 182.160 108.512 1.00 63.89  ? 158 THR C CB  1 
ATOM   10433 O OG1 . THR C 1 158 ? 109.619 182.593 107.196 1.00 63.58  ? 158 THR C OG1 1 
ATOM   10434 C CG2 . THR C 1 158 ? 109.360 183.421 109.375 1.00 63.35  ? 158 THR C CG2 1 
ATOM   10435 N N   . ASP C 1 159 ? 109.505 179.415 110.550 1.00 59.73  ? 159 ASP C N   1 
ATOM   10436 C CA  . ASP C 1 159 ? 109.174 178.873 111.877 1.00 61.46  ? 159 ASP C CA  1 
ATOM   10437 C C   . ASP C 1 159 ? 110.406 178.429 112.685 1.00 60.26  ? 159 ASP C C   1 
ATOM   10438 O O   . ASP C 1 159 ? 111.487 178.222 112.145 1.00 63.11  ? 159 ASP C O   1 
ATOM   10439 C CB  . ASP C 1 159 ? 108.227 177.689 111.722 1.00 64.05  ? 159 ASP C CB  1 
ATOM   10440 C CG  . ASP C 1 159 ? 108.947 176.502 111.085 1.00 63.66  ? 159 ASP C CG  1 
ATOM   10441 O OD1 . ASP C 1 159 ? 109.088 176.495 109.845 1.00 62.13  ? 159 ASP C OD1 1 
ATOM   10442 O OD2 . ASP C 1 159 ? 109.386 175.623 111.856 1.00 61.39  ? 159 ASP C OD2 1 
ATOM   10443 N N   . GLU C 1 160 ? 110.236 178.212 113.991 1.00 58.47  ? 160 GLU C N   1 
ATOM   10444 C CA  . GLU C 1 160 ? 111.322 177.851 114.905 1.00 58.11  ? 160 GLU C CA  1 
ATOM   10445 C C   . GLU C 1 160 ? 112.082 176.565 114.525 1.00 60.35  ? 160 GLU C C   1 
ATOM   10446 O O   . GLU C 1 160 ? 113.278 176.470 114.793 1.00 60.48  ? 160 GLU C O   1 
ATOM   10447 C CB  . GLU C 1 160 ? 110.733 177.751 116.324 1.00 58.56  ? 160 GLU C CB  1 
ATOM   10448 C CG  . GLU C 1 160 ? 111.755 177.377 117.404 1.00 60.84  ? 160 GLU C CG  1 
ATOM   10449 C CD  . GLU C 1 160 ? 111.241 177.551 118.844 1.00 64.73  ? 160 GLU C CD  1 
ATOM   10450 O OE1 . GLU C 1 160 ? 110.025 177.721 119.071 1.00 62.53  ? 160 GLU C OE1 1 
ATOM   10451 O OE2 . GLU C 1 160 ? 112.065 177.506 119.773 1.00 64.50  ? 160 GLU C OE2 1 
ATOM   10452 N N   . PHE C 1 161 ? 111.440 175.573 113.900 1.00 52.76  ? 161 PHE C N   1 
ATOM   10453 C CA  . PHE C 1 161 ? 112.101 174.317 113.541 1.00 48.94  ? 161 PHE C CA  1 
ATOM   10454 C C   . PHE C 1 161 ? 112.801 174.382 112.193 1.00 50.48  ? 161 PHE C C   1 
ATOM   10455 O O   . PHE C 1 161 ? 113.939 173.919 112.106 1.00 52.55  ? 161 PHE C O   1 
ATOM   10456 C CB  . PHE C 1 161 ? 111.139 173.131 113.627 1.00 45.27  ? 161 PHE C CB  1 
ATOM   10457 C CG  . PHE C 1 161 ? 111.104 172.566 115.028 1.00 51.87  ? 161 PHE C CG  1 
ATOM   10458 C CD1 . PHE C 1 161 ? 110.356 173.201 116.034 1.00 53.50  ? 161 PHE C CD1 1 
ATOM   10459 C CD2 . PHE C 1 161 ? 111.906 171.457 115.348 1.00 51.46  ? 161 PHE C CD2 1 
ATOM   10460 C CE1 . PHE C 1 161 ? 110.412 172.727 117.355 1.00 54.39  ? 161 PHE C CE1 1 
ATOM   10461 C CE2 . PHE C 1 161 ? 111.963 170.983 116.666 1.00 53.28  ? 161 PHE C CE2 1 
ATOM   10462 C CZ  . PHE C 1 161 ? 111.215 171.621 117.672 1.00 55.25  ? 161 PHE C CZ  1 
ATOM   10463 N N   . TYR C 1 162 ? 112.190 174.976 111.170 1.00 46.24  ? 162 TYR C N   1 
ATOM   10464 C CA  . TYR C 1 162 ? 112.745 174.964 109.816 1.00 42.24  ? 162 TYR C CA  1 
ATOM   10465 C C   . TYR C 1 162 ? 113.323 176.305 109.338 1.00 49.28  ? 162 TYR C C   1 
ATOM   10466 O O   . TYR C 1 162 ? 113.621 176.440 108.157 1.00 49.20  ? 162 TYR C O   1 
ATOM   10467 C CB  . TYR C 1 162 ? 111.767 174.315 108.830 1.00 46.28  ? 162 TYR C CB  1 
ATOM   10468 C CG  . TYR C 1 162 ? 111.225 172.987 109.322 1.00 48.50  ? 162 TYR C CG  1 
ATOM   10469 C CD1 . TYR C 1 162 ? 112.073 171.862 109.376 1.00 47.06  ? 162 TYR C CD1 1 
ATOM   10470 C CD2 . TYR C 1 162 ? 109.911 172.892 109.802 1.00 49.83  ? 162 TYR C CD2 1 
ATOM   10471 C CE1 . TYR C 1 162 ? 111.606 170.657 109.919 1.00 45.25  ? 162 TYR C CE1 1 
ATOM   10472 C CE2 . TYR C 1 162 ? 109.439 171.683 110.350 1.00 45.66  ? 162 TYR C CE2 1 
ATOM   10473 C CZ  . TYR C 1 162 ? 110.294 170.569 110.414 1.00 44.97  ? 162 TYR C CZ  1 
ATOM   10474 O OH  . TYR C 1 162 ? 109.857 169.413 110.967 1.00 50.00  ? 162 TYR C OH  1 
ATOM   10475 N N   . GLN C 1 163 ? 113.537 177.288 110.224 1.00 51.48  ? 163 GLN C N   1 
ATOM   10476 C CA  . GLN C 1 163 ? 114.062 178.612 109.866 1.00 51.99  ? 163 GLN C CA  1 
ATOM   10477 C C   . GLN C 1 163 ? 115.265 178.557 108.908 1.00 52.81  ? 163 GLN C C   1 
ATOM   10478 O O   . GLN C 1 163 ? 116.253 177.868 109.159 1.00 55.12  ? 163 GLN C O   1 
ATOM   10479 C CB  . GLN C 1 163 ? 114.432 179.399 111.132 1.00 52.23  ? 163 GLN C CB  1 
ATOM   10480 C CG  . GLN C 1 163 ? 114.773 180.863 110.823 1.00 54.51  ? 163 GLN C CG  1 
ATOM   10481 C CD  . GLN C 1 163 ? 114.889 181.727 112.072 1.00 57.59  ? 163 GLN C CD  1 
ATOM   10482 O OE1 . GLN C 1 163 ? 115.043 181.260 113.190 1.00 55.68  ? 163 GLN C OE1 1 
ATOM   10483 N NE2 . GLN C 1 163 ? 114.824 183.028 111.932 1.00 56.54  ? 163 GLN C NE2 1 
ATOM   10484 N N   . GLY C 1 164 ? 115.191 179.309 107.814 1.00 52.46  ? 164 GLY C N   1 
ATOM   10485 C CA  . GLY C 1 164 ? 116.275 179.439 106.844 1.00 48.54  ? 164 GLY C CA  1 
ATOM   10486 C C   . GLY C 1 164 ? 116.376 178.315 105.810 1.00 47.22  ? 164 GLY C C   1 
ATOM   10487 O O   . GLY C 1 164 ? 117.187 178.412 104.892 1.00 54.57  ? 164 GLY C O   1 
ATOM   10488 N N   . HIS C 1 165 ? 115.478 177.339 105.884 1.00 44.24  ? 165 HIS C N   1 
ATOM   10489 C CA  . HIS C 1 165 ? 115.422 176.244 104.881 1.00 42.67  ? 165 HIS C CA  1 
ATOM   10490 C C   . HIS C 1 165 ? 115.008 176.847 103.550 1.00 48.32  ? 165 HIS C C   1 
ATOM   10491 O O   . HIS C 1 165 ? 114.218 177.771 103.577 1.00 54.20  ? 165 HIS C O   1 
ATOM   10492 C CB  . HIS C 1 165 ? 114.479 175.143 105.349 1.00 48.71  ? 165 HIS C CB  1 
ATOM   10493 C CG  . HIS C 1 165 ? 114.500 173.889 104.548 1.00 48.72  ? 165 HIS C CG  1 
ATOM   10494 N ND1 . HIS C 1 165 ? 115.655 173.367 104.027 1.00 50.04  ? 165 HIS C ND1 1 
ATOM   10495 C CD2 . HIS C 1 165 ? 113.513 173.040 104.206 1.00 47.28  ? 165 HIS C CD2 1 
ATOM   10496 C CE1 . HIS C 1 165 ? 115.378 172.256 103.384 1.00 49.19  ? 165 HIS C CE1 1 
ATOM   10497 N NE2 . HIS C 1 165 ? 114.075 172.031 103.481 1.00 45.32  ? 165 HIS C NE2 1 
ATOM   10498 N N   . SER C 1 166 ? 115.481 176.306 102.433 1.00 47.04  ? 166 SER C N   1 
ATOM   10499 C CA  . SER C 1 166 ? 115.281 176.940 101.123 1.00 46.49  ? 166 SER C CA  1 
ATOM   10500 C C   . SER C 1 166 ? 115.134 175.924 99.992  1.00 47.33  ? 166 SER C C   1 
ATOM   10501 O O   . SER C 1 166 ? 115.493 174.757 100.135 1.00 49.33  ? 166 SER C O   1 
ATOM   10502 C CB  . SER C 1 166 ? 116.433 177.911 100.829 1.00 51.74  ? 166 SER C CB  1 
ATOM   10503 O OG  . SER C 1 166 ? 117.598 177.230 100.411 1.00 52.60  ? 166 SER C OG  1 
ATOM   10504 N N   . ALA C 1 167 ? 114.643 176.356 98.829  1.00 47.91  ? 167 ALA C N   1 
ATOM   10505 C CA  . ALA C 1 167 ? 114.502 175.484 97.666  1.00 49.85  ? 167 ALA C CA  1 
ATOM   10506 C C   . ALA C 1 167 ? 115.831 174.840 97.224  1.00 49.78  ? 167 ALA C C   1 
ATOM   10507 O O   . ALA C 1 167 ? 115.835 173.696 96.781  1.00 48.28  ? 167 ALA C O   1 
ATOM   10508 C CB  . ALA C 1 167 ? 113.873 176.306 96.535  1.00 49.79  ? 167 ALA C CB  1 
ATOM   10509 N N   . LEU C 1 168 ? 116.967 175.525 97.404  1.00 47.31  ? 168 LEU C N   1 
ATOM   10510 C CA  . LEU C 1 168 ? 118.292 174.981 97.094  1.00 47.78  ? 168 LEU C CA  1 
ATOM   10511 C C   . LEU C 1 168 ? 118.693 173.840 98.042  1.00 42.89  ? 168 LEU C C   1 
ATOM   10512 O O   . LEU C 1 168 ? 119.186 172.815 97.585  1.00 42.13  ? 168 LEU C O   1 
ATOM   10513 C CB  . LEU C 1 168 ? 119.307 176.136 97.077  1.00 47.83  ? 168 LEU C CB  1 
ATOM   10514 C CG  . LEU C 1 168 ? 120.748 175.706 96.749  1.00 47.91  ? 168 LEU C CG  1 
ATOM   10515 C CD1 . LEU C 1 168 ? 120.873 175.037 95.383  1.00 42.36  ? 168 LEU C CD1 1 
ATOM   10516 C CD2 . LEU C 1 168 ? 121.665 176.923 96.755  1.00 47.90  ? 168 LEU C CD2 1 
ATOM   10517 N N   . HIS C 1 169 ? 118.417 173.957 99.343  1.00 37.43  ? 169 HIS C N   1 
ATOM   10518 C CA  . HIS C 1 169 ? 118.596 172.845 100.280 1.00 37.14  ? 169 HIS C CA  1 
ATOM   10519 C C   . HIS C 1 169 ? 117.744 171.635 99.893  1.00 41.28  ? 169 HIS C C   1 
ATOM   10520 O O   . HIS C 1 169 ? 118.273 170.507 99.948  1.00 41.83  ? 169 HIS C O   1 
ATOM   10521 C CB  . HIS C 1 169 ? 118.260 173.305 101.707 1.00 38.00  ? 169 HIS C CB  1 
ATOM   10522 C CG  . HIS C 1 169 ? 119.275 174.219 102.311 1.00 40.71  ? 169 HIS C CG  1 
ATOM   10523 N ND1 . HIS C 1 169 ? 118.963 175.503 102.716 1.00 38.21  ? 169 HIS C ND1 1 
ATOM   10524 C CD2 . HIS C 1 169 ? 120.584 174.041 102.590 1.00 37.10  ? 169 HIS C CD2 1 
ATOM   10525 C CE1 . HIS C 1 169 ? 120.039 176.079 103.215 1.00 37.16  ? 169 HIS C CE1 1 
ATOM   10526 N NE2 . HIS C 1 169 ? 121.047 175.201 103.150 1.00 40.97  ? 169 HIS C NE2 1 
ATOM   10527 N N   . ILE C 1 170 ? 116.487 171.853 99.495  1.00 45.07  ? 170 ILE C N   1 
ATOM   10528 C CA  . ILE C 1 170 ? 115.602 170.775 99.029  1.00 40.02  ? 170 ILE C CA  1 
ATOM   10529 C C   . ILE C 1 170 ? 116.140 170.135 97.745  1.00 43.81  ? 170 ILE C C   1 
ATOM   10530 O O   . ILE C 1 170 ? 116.196 168.912 97.670  1.00 44.41  ? 170 ILE C O   1 
ATOM   10531 C CB  . ILE C 1 170 ? 114.148 171.259 98.857  1.00 47.81  ? 170 ILE C CB  1 
ATOM   10532 C CG1 . ILE C 1 170 ? 113.589 171.860 100.161 1.00 44.88  ? 170 ILE C CG1 1 
ATOM   10533 C CG2 . ILE C 1 170 ? 113.235 170.100 98.428  1.00 45.86  ? 170 ILE C CG2 1 
ATOM   10534 C CD1 . ILE C 1 170 ? 112.273 172.615 99.976  1.00 46.62  ? 170 ILE C CD1 1 
ATOM   10535 N N   . ALA C 1 171 ? 116.575 170.914 96.750  1.00 42.00  ? 171 ALA C N   1 
ATOM   10536 C CA  . ALA C 1 171 ? 117.129 170.379 95.507  1.00 39.18  ? 171 ALA C CA  1 
ATOM   10537 C C   . ALA C 1 171 ? 118.378 169.512 95.746  1.00 43.51  ? 171 ALA C C   1 
ATOM   10538 O O   . ALA C 1 171 ? 118.524 168.449 95.143  1.00 41.92  ? 171 ALA C O   1 
ATOM   10539 C CB  . ALA C 1 171 ? 117.443 171.549 94.573  1.00 40.49  ? 171 ALA C CB  1 
ATOM   10540 N N   . ILE C 1 172 ? 119.253 169.944 96.661  1.00 46.49  ? 172 ILE C N   1 
ATOM   10541 C CA  . ILE C 1 172 ? 120.440 169.189 97.063  1.00 39.84  ? 172 ILE C CA  1 
ATOM   10542 C C   . ILE C 1 172 ? 120.033 167.894 97.764  1.00 42.36  ? 172 ILE C C   1 
ATOM   10543 O O   . ILE C 1 172 ? 120.453 166.834 97.323  1.00 43.71  ? 172 ILE C O   1 
ATOM   10544 C CB  . ILE C 1 172 ? 121.388 170.058 97.912  1.00 40.89  ? 172 ILE C CB  1 
ATOM   10545 C CG1 . ILE C 1 172 ? 121.932 171.207 97.041  1.00 42.53  ? 172 ILE C CG1 1 
ATOM   10546 C CG2 . ILE C 1 172 ? 122.561 169.249 98.486  1.00 34.68  ? 172 ILE C CG2 1 
ATOM   10547 C CD1 . ILE C 1 172 ? 122.652 172.290 97.823  1.00 40.21  ? 172 ILE C CD1 1 
ATOM   10548 N N   . GLU C 1 173 ? 119.179 167.918 98.785  1.00 40.71  ? 173 GLU C N   1 
ATOM   10549 C CA  . GLU C 1 173 ? 118.738 166.688 99.468  1.00 38.66  ? 173 GLU C CA  1 
ATOM   10550 C C   . GLU C 1 173 ? 117.936 165.743 98.551  1.00 44.94  ? 173 GLU C C   1 
ATOM   10551 O O   . GLU C 1 173 ? 118.085 164.525 98.643  1.00 46.37  ? 173 GLU C O   1 
ATOM   10552 C CB  . GLU C 1 173 ? 117.979 167.075 100.744 1.00 44.81  ? 173 GLU C CB  1 
ATOM   10553 C CG  . GLU C 1 173 ? 117.138 165.986 101.432 1.00 46.59  ? 173 GLU C CG  1 
ATOM   10554 C CD  . GLU C 1 173 ? 117.779 164.604 101.589 1.00 49.52  ? 173 GLU C CD  1 
ATOM   10555 O OE1 . GLU C 1 173 ? 119.022 164.512 101.728 1.00 51.02  ? 173 GLU C OE1 1 
ATOM   10556 O OE2 . GLU C 1 173 ? 117.010 163.617 101.629 1.00 46.27  ? 173 GLU C OE2 1 
ATOM   10557 N N   . LYS C 1 174 ? 117.147 166.250 97.596  1.00 48.54  ? 174 LYS C N   1 
ATOM   10558 C CA  . LYS C 1 174 ? 116.491 165.441 96.553  1.00 44.59  ? 174 LYS C CA  1 
ATOM   10559 C C   . LYS C 1 174 ? 117.442 164.929 95.457  1.00 47.17  ? 174 LYS C C   1 
ATOM   10560 O O   . LYS C 1 174 ? 116.996 164.237 94.546  1.00 50.48  ? 174 LYS C O   1 
ATOM   10561 C CB  . LYS C 1 174 ? 115.280 166.197 95.983  1.00 46.75  ? 174 LYS C CB  1 
ATOM   10562 C CG  . LYS C 1 174 ? 114.100 166.295 96.973  1.00 48.95  ? 174 LYS C CG  1 
ATOM   10563 C CD  . LYS C 1 174 ? 113.407 164.941 97.178  1.00 47.01  ? 174 LYS C CD  1 
ATOM   10564 C CE  . LYS C 1 174 ? 112.267 165.024 98.199  1.00 48.20  ? 174 LYS C CE  1 
ATOM   10565 N NZ  . LYS C 1 174 ? 111.739 163.673 98.515  1.00 50.28  ? 174 LYS C NZ  1 
ATOM   10566 N N   . ARG C 1 175 ? 118.746 165.220 95.560  1.00 46.26  ? 175 ARG C N   1 
ATOM   10567 C CA  . ARG C 1 175 ? 119.854 164.736 94.709  1.00 40.97  ? 175 ARG C CA  1 
ATOM   10568 C C   . ARG C 1 175 ? 119.761 165.128 93.228  1.00 45.43  ? 175 ARG C C   1 
ATOM   10569 O O   . ARG C 1 175 ? 120.344 164.458 92.378  1.00 48.21  ? 175 ARG C O   1 
ATOM   10570 C CB  . ARG C 1 175 ? 120.128 163.232 94.937  1.00 42.41  ? 175 ARG C CB  1 
ATOM   10571 C CG  . ARG C 1 175 ? 120.294 162.855 96.412  1.00 42.95  ? 175 ARG C CG  1 
ATOM   10572 C CD  . ARG C 1 175 ? 120.682 161.388 96.636  1.00 41.98  ? 175 ARG C CD  1 
ATOM   10573 N NE  . ARG C 1 175 ? 122.080 161.082 96.272  1.00 46.21  ? 175 ARG C NE  1 
ATOM   10574 C CZ  . ARG C 1 175 ? 123.151 161.188 97.036  1.00 48.84  ? 175 ARG C CZ  1 
ATOM   10575 N NH1 . ARG C 1 175 ? 124.303 160.750 96.635  1.00 46.57  ? 175 ARG C NH1 1 
ATOM   10576 N NH2 . ARG C 1 175 ? 123.103 161.747 98.205  1.00 45.51  ? 175 ARG C NH2 1 
ATOM   10577 N N   . SER C 1 176 ? 119.059 166.213 92.901  1.00 53.84  ? 176 SER C N   1 
ATOM   10578 C CA  . SER C 1 176 ? 118.941 166.697 91.520  1.00 55.41  ? 176 SER C CA  1 
ATOM   10579 C C   . SER C 1 176 ? 119.968 167.784 91.210  1.00 59.60  ? 176 SER C C   1 
ATOM   10580 O O   . SER C 1 176 ? 119.759 168.966 91.482  1.00 62.21  ? 176 SER C O   1 
ATOM   10581 C CB  . SER C 1 176 ? 117.518 167.167 91.219  1.00 57.59  ? 176 SER C CB  1 
ATOM   10582 O OG  . SER C 1 176 ? 117.464 167.658 89.891  1.00 60.39  ? 176 SER C OG  1 
ATOM   10583 N N   . LEU C 1 177 ? 121.079 167.400 90.579  1.00 53.30  ? 177 LEU C N   1 
ATOM   10584 C CA  . LEU C 1 177 ? 122.043 168.356 90.040  1.00 54.95  ? 177 LEU C CA  1 
ATOM   10585 C C   . LEU C 1 177 ? 121.420 169.232 88.942  1.00 58.77  ? 177 LEU C C   1 
ATOM   10586 O O   . LEU C 1 177 ? 121.717 170.419 88.873  1.00 60.49  ? 177 LEU C O   1 
ATOM   10587 C CB  . LEU C 1 177 ? 123.278 167.586 89.556  1.00 58.41  ? 177 LEU C CB  1 
ATOM   10588 C CG  . LEU C 1 177 ? 124.356 168.456 88.890  1.00 58.50  ? 177 LEU C CG  1 
ATOM   10589 C CD1 . LEU C 1 177 ? 124.898 169.533 89.826  1.00 55.66  ? 177 LEU C CD1 1 
ATOM   10590 C CD2 . LEU C 1 177 ? 125.512 167.560 88.467  1.00 55.77  ? 177 LEU C CD2 1 
ATOM   10591 N N   . GLN C 1 178 ? 120.501 168.693 88.138  1.00 60.63  ? 178 GLN C N   1 
ATOM   10592 C CA  . GLN C 1 178 ? 119.716 169.453 87.162  1.00 57.39  ? 178 GLN C CA  1 
ATOM   10593 C C   . GLN C 1 178 ? 118.946 170.600 87.824  1.00 59.61  ? 178 GLN C C   1 
ATOM   10594 O O   . GLN C 1 178 ? 118.978 171.730 87.347  1.00 60.93  ? 178 GLN C O   1 
ATOM   10595 C CB  . GLN C 1 178 ? 118.727 168.524 86.431  1.00 60.02  ? 178 GLN C CB  1 
ATOM   10596 C CG  . GLN C 1 178 ? 119.368 167.407 85.591  1.00 60.93  ? 178 GLN C CG  1 
ATOM   10597 C CD  . GLN C 1 178 ? 119.594 166.090 86.331  1.00 63.10  ? 178 GLN C CD  1 
ATOM   10598 O OE1 . GLN C 1 178 ? 119.864 166.034 87.521  1.00 63.21  ? 178 GLN C OE1 1 
ATOM   10599 N NE2 . GLN C 1 178 ? 119.514 164.970 85.649  1.00 62.38  ? 178 GLN C NE2 1 
ATOM   10600 N N   . CYS C 1 179 ? 118.280 170.336 88.949  1.00 57.63  ? 179 CYS C N   1 
ATOM   10601 C CA  . CYS C 1 179 ? 117.540 171.350 89.689  1.00 58.37  ? 179 CYS C CA  1 
ATOM   10602 C C   . CYS C 1 179 ? 118.469 172.340 90.413  1.00 61.15  ? 179 CYS C C   1 
ATOM   10603 O O   . CYS C 1 179 ? 118.213 173.542 90.387  1.00 58.28  ? 179 CYS C O   1 
ATOM   10604 C CB  . CYS C 1 179 ? 116.577 170.628 90.636  1.00 57.64  ? 179 CYS C CB  1 
ATOM   10605 S SG  . CYS C 1 179 ? 115.412 171.804 91.355  1.00 65.71  ? 179 CYS C SG  1 
ATOM   10606 N N   . VAL C 1 180 ? 119.593 171.882 90.983  1.00 56.94  ? 180 VAL C N   1 
ATOM   10607 C CA  . VAL C 1 180 ? 120.613 172.767 91.575  1.00 55.94  ? 180 VAL C CA  1 
ATOM   10608 C C   . VAL C 1 180 ? 121.182 173.731 90.534  1.00 55.90  ? 180 VAL C C   1 
ATOM   10609 O O   . VAL C 1 180 ? 121.201 174.938 90.771  1.00 51.90  ? 180 VAL C O   1 
ATOM   10610 C CB  . VAL C 1 180 ? 121.736 171.957 92.255  1.00 56.80  ? 180 VAL C CB  1 
ATOM   10611 C CG1 . VAL C 1 180 ? 122.918 172.834 92.668  1.00 56.73  ? 180 VAL C CG1 1 
ATOM   10612 C CG2 . VAL C 1 180 ? 121.211 171.262 93.513  1.00 50.70  ? 180 VAL C CG2 1 
ATOM   10613 N N   . LYS C 1 181 ? 121.572 173.236 89.351  1.00 57.73  ? 181 LYS C N   1 
ATOM   10614 C CA  . LYS C 1 181 ? 122.010 174.066 88.226  1.00 54.72  ? 181 LYS C CA  1 
ATOM   10615 C C   . LYS C 1 181 ? 120.954 175.104 87.849  1.00 56.10  ? 181 LYS C C   1 
ATOM   10616 O O   . LYS C 1 181 ? 121.263 176.284 87.760  1.00 58.39  ? 181 LYS C O   1 
ATOM   10617 C CB  . LYS C 1 181 ? 122.338 173.188 87.010  1.00 54.77  ? 181 LYS C CB  1 
ATOM   10618 C CG  . LYS C 1 181 ? 123.671 172.451 87.156  1.00 57.95  ? 181 LYS C CG  1 
ATOM   10619 C CD  . LYS C 1 181 ? 123.951 171.566 85.943  1.00 55.32  ? 181 LYS C CD  1 
ATOM   10620 C CE  . LYS C 1 181 ? 125.335 170.929 86.065  1.00 58.46  ? 181 LYS C CE  1 
ATOM   10621 N NZ  . LYS C 1 181 ? 125.700 170.177 84.845  1.00 59.62  ? 181 LYS C NZ  1 
ATOM   10622 N N   . LEU C 1 182 ? 119.703 174.677 87.681  1.00 62.48  ? 182 LEU C N   1 
ATOM   10623 C CA  . LEU C 1 182 ? 118.579 175.539 87.309  1.00 63.59  ? 182 LEU C CA  1 
ATOM   10624 C C   . LEU C 1 182 ? 118.340 176.663 88.334  1.00 64.68  ? 182 LEU C C   1 
ATOM   10625 O O   . LEU C 1 182 ? 118.161 177.817 87.952  1.00 65.73  ? 182 LEU C O   1 
ATOM   10626 C CB  . LEU C 1 182 ? 117.360 174.611 87.118  1.00 63.05  ? 182 LEU C CB  1 
ATOM   10627 C CG  . LEU C 1 182 ? 116.147 175.165 86.359  1.00 64.99  ? 182 LEU C CG  1 
ATOM   10628 C CD1 . LEU C 1 182 ? 115.208 173.996 86.081  1.00 65.72  ? 182 LEU C CD1 1 
ATOM   10629 C CD2 . LEU C 1 182 ? 115.359 176.214 87.130  1.00 64.85  ? 182 LEU C CD2 1 
ATOM   10630 N N   . LEU C 1 183 ? 118.385 176.353 89.629  1.00 62.07  ? 183 LEU C N   1 
ATOM   10631 C CA  . LEU C 1 183 ? 118.247 177.333 90.710  1.00 62.44  ? 183 LEU C CA  1 
ATOM   10632 C C   . LEU C 1 183 ? 119.436 178.304 90.775  1.00 62.36  ? 183 LEU C C   1 
ATOM   10633 O O   . LEU C 1 183 ? 119.239 179.515 90.867  1.00 62.52  ? 183 LEU C O   1 
ATOM   10634 C CB  . LEU C 1 183 ? 118.074 176.582 92.041  1.00 64.28  ? 183 LEU C CB  1 
ATOM   10635 C CG  . LEU C 1 183 ? 116.731 175.846 92.210  1.00 63.77  ? 183 LEU C CG  1 
ATOM   10636 C CD1 . LEU C 1 183 ? 116.805 174.977 93.459  1.00 59.74  ? 183 LEU C CD1 1 
ATOM   10637 C CD2 . LEU C 1 183 ? 115.558 176.801 92.390  1.00 63.64  ? 183 LEU C CD2 1 
ATOM   10638 N N   . VAL C 1 184 ? 120.673 177.807 90.691  1.00 65.58  ? 184 VAL C N   1 
ATOM   10639 C CA  . VAL C 1 184 ? 121.880 178.645 90.771  1.00 65.10  ? 184 VAL C CA  1 
ATOM   10640 C C   . VAL C 1 184 ? 122.028 179.552 89.542  1.00 66.00  ? 184 VAL C C   1 
ATOM   10641 O O   . VAL C 1 184 ? 122.324 180.734 89.696  1.00 66.98  ? 184 VAL C O   1 
ATOM   10642 C CB  . VAL C 1 184 ? 123.117 177.765 91.029  1.00 62.91  ? 184 VAL C CB  1 
ATOM   10643 C CG1 . VAL C 1 184 ? 124.435 178.528 90.893  1.00 61.25  ? 184 VAL C CG1 1 
ATOM   10644 C CG2 . VAL C 1 184 ? 123.065 177.203 92.457  1.00 61.08  ? 184 VAL C CG2 1 
ATOM   10645 N N   . GLU C 1 185 ? 121.708 179.067 88.339  1.00 64.04  ? 185 GLU C N   1 
ATOM   10646 C CA  . GLU C 1 185 ? 121.586 179.899 87.131  1.00 63.27  ? 185 GLU C CA  1 
ATOM   10647 C C   . GLU C 1 185 ? 120.590 181.058 87.284  1.00 67.14  ? 185 GLU C C   1 
ATOM   10648 O O   . GLU C 1 185 ? 120.762 182.108 86.667  1.00 68.44  ? 185 GLU C O   1 
ATOM   10649 C CB  . GLU C 1 185 ? 121.131 179.026 85.949  1.00 64.04  ? 185 GLU C CB  1 
ATOM   10650 C CG  . GLU C 1 185 ? 122.246 178.127 85.400  1.00 64.30  ? 185 GLU C CG  1 
ATOM   10651 C CD  . GLU C 1 185 ? 121.735 176.953 84.544  1.00 67.63  ? 185 GLU C CD  1 
ATOM   10652 O OE1 . GLU C 1 185 ? 120.576 176.973 84.073  1.00 67.54  ? 185 GLU C OE1 1 
ATOM   10653 O OE2 . GLU C 1 185 ? 122.531 176.021 84.280  1.00 67.10  ? 185 GLU C OE2 1 
ATOM   10654 N N   . ASN C 1 186 ? 119.550 180.890 88.107  1.00 67.55  ? 186 ASN C N   1 
ATOM   10655 C CA  . ASN C 1 186 ? 118.513 181.890 88.365  1.00 66.16  ? 186 ASN C CA  1 
ATOM   10656 C C   . ASN C 1 186 ? 118.739 182.723 89.643  1.00 67.95  ? 186 ASN C C   1 
ATOM   10657 O O   . ASN C 1 186 ? 117.847 183.453 90.070  1.00 68.18  ? 186 ASN C O   1 
ATOM   10658 C CB  . ASN C 1 186 ? 117.141 181.208 88.303  1.00 67.82  ? 186 ASN C CB  1 
ATOM   10659 C CG  . ASN C 1 186 ? 116.724 180.994 86.867  1.00 69.56  ? 186 ASN C CG  1 
ATOM   10660 O OD1 . ASN C 1 186 ? 116.205 181.896 86.219  1.00 71.14  ? 186 ASN C OD1 1 
ATOM   10661 N ND2 . ASN C 1 186 ? 116.946 179.826 86.316  1.00 68.22  ? 186 ASN C ND2 1 
ATOM   10662 N N   . GLY C 1 187 ? 119.923 182.659 90.253  1.00 67.30  ? 187 GLY C N   1 
ATOM   10663 C CA  . GLY C 1 187 ? 120.293 183.527 91.375  1.00 65.30  ? 187 GLY C CA  1 
ATOM   10664 C C   . GLY C 1 187 ? 120.002 182.974 92.774  1.00 66.03  ? 187 GLY C C   1 
ATOM   10665 O O   . GLY C 1 187 ? 119.881 183.758 93.719  1.00 64.72  ? 187 GLY C O   1 
ATOM   10666 N N   . ALA C 1 188 ? 119.906 181.650 92.936  1.00 65.30  ? 188 ALA C N   1 
ATOM   10667 C CA  . ALA C 1 188 ? 119.902 181.025 94.259  1.00 62.54  ? 188 ALA C CA  1 
ATOM   10668 C C   . ALA C 1 188 ? 121.189 181.358 95.035  1.00 65.14  ? 188 ALA C C   1 
ATOM   10669 O O   . ALA C 1 188 ? 122.294 181.058 94.589  1.00 67.46  ? 188 ALA C O   1 
ATOM   10670 C CB  . ALA C 1 188 ? 119.738 179.511 94.120  1.00 61.67  ? 188 ALA C CB  1 
ATOM   10671 N N   . ASP C 1 189 ? 121.050 181.964 96.208  1.00 62.71  ? 189 ASP C N   1 
ATOM   10672 C CA  . ASP C 1 189 ? 122.159 182.261 97.107  1.00 57.50  ? 189 ASP C CA  1 
ATOM   10673 C C   . ASP C 1 189 ? 122.687 180.970 97.749  1.00 61.34  ? 189 ASP C C   1 
ATOM   10674 O O   . ASP C 1 189 ? 121.990 180.287 98.498  1.00 63.15  ? 189 ASP C O   1 
ATOM   10675 C CB  . ASP C 1 189 ? 121.714 183.292 98.155  1.00 56.93  ? 189 ASP C CB  1 
ATOM   10676 C CG  . ASP C 1 189 ? 122.836 183.688 99.127  1.00 63.87  ? 189 ASP C CG  1 
ATOM   10677 O OD1 . ASP C 1 189 ? 123.995 183.272 98.914  1.00 65.06  ? 189 ASP C OD1 1 
ATOM   10678 O OD2 . ASP C 1 189 ? 122.557 184.458 100.070 1.00 64.28  ? 189 ASP C OD2 1 
ATOM   10679 N N   . VAL C 1 190 ? 123.939 180.631 97.460  1.00 55.81  ? 190 VAL C N   1 
ATOM   10680 C CA  . VAL C 1 190 ? 124.584 179.410 97.947  1.00 52.62  ? 190 VAL C CA  1 
ATOM   10681 C C   . VAL C 1 190 ? 125.003 179.521 99.423  1.00 51.90  ? 190 VAL C C   1 
ATOM   10682 O O   . VAL C 1 190 ? 125.440 178.543 100.015 1.00 54.55  ? 190 VAL C O   1 
ATOM   10683 C CB  . VAL C 1 190 ? 125.739 179.005 97.006  1.00 53.18  ? 190 VAL C CB  1 
ATOM   10684 C CG1 . VAL C 1 190 ? 126.223 177.582 97.271  1.00 55.26  ? 190 VAL C CG1 1 
ATOM   10685 C CG2 . VAL C 1 190 ? 125.309 179.032 95.534  1.00 50.73  ? 190 VAL C CG2 1 
ATOM   10686 N N   . HIS C 1 191 ? 124.846 180.689 100.056 1.00 53.07  ? 191 HIS C N   1 
ATOM   10687 C CA  . HIS C 1 191 ? 125.232 180.941 101.450 1.00 51.70  ? 191 HIS C CA  1 
ATOM   10688 C C   . HIS C 1 191 ? 124.056 181.099 102.422 1.00 53.46  ? 191 HIS C C   1 
ATOM   10689 O O   . HIS C 1 191 ? 124.226 181.654 103.508 1.00 55.90  ? 191 HIS C O   1 
ATOM   10690 C CB  . HIS C 1 191 ? 126.168 182.159 101.501 1.00 55.35  ? 191 HIS C CB  1 
ATOM   10691 C CG  . HIS C 1 191 ? 127.401 181.981 100.679 1.00 56.76  ? 191 HIS C CG  1 
ATOM   10692 N ND1 . HIS C 1 191 ? 128.578 181.488 101.209 1.00 53.20  ? 191 HIS C ND1 1 
ATOM   10693 C CD2 . HIS C 1 191 ? 127.643 182.214 99.370  1.00 54.86  ? 191 HIS C CD2 1 
ATOM   10694 C CE1 . HIS C 1 191 ? 129.494 181.430 100.263 1.00 54.53  ? 191 HIS C CE1 1 
ATOM   10695 N NE2 . HIS C 1 191 ? 128.943 181.870 99.125  1.00 56.23  ? 191 HIS C NE2 1 
ATOM   10696 N N   . LEU C 1 192 ? 122.852 180.629 102.078 1.00 55.46  ? 192 LEU C N   1 
ATOM   10697 C CA  . LEU C 1 192 ? 121.718 180.606 103.013 1.00 50.97  ? 192 LEU C CA  1 
ATOM   10698 C C   . LEU C 1 192 ? 121.929 179.567 104.124 1.00 50.27  ? 192 LEU C C   1 
ATOM   10699 O O   . LEU C 1 192 ? 122.238 178.412 103.839 1.00 51.79  ? 192 LEU C O   1 
ATOM   10700 C CB  . LEU C 1 192 ? 120.415 180.309 102.249 1.00 50.96  ? 192 LEU C CB  1 
ATOM   10701 C CG  . LEU C 1 192 ? 120.044 181.351 101.182 1.00 55.37  ? 192 LEU C CG  1 
ATOM   10702 C CD1 . LEU C 1 192 ? 118.768 180.926 100.462 1.00 53.04  ? 192 LEU C CD1 1 
ATOM   10703 C CD2 . LEU C 1 192 ? 119.824 182.737 101.778 1.00 53.25  ? 192 LEU C CD2 1 
ATOM   10704 N N   . ARG C 1 193 ? 121.616 179.932 105.380 1.00 46.32  ? 193 ARG C N   1 
ATOM   10705 C CA  . ARG C 1 193 ? 121.840 178.992 106.522 1.00 45.39  ? 193 ARG C CA  1 
ATOM   10706 C C   . ARG C 1 193 ? 120.563 178.390 107.098 1.00 45.01  ? 193 ARG C C   1 
ATOM   10707 O O   . ARG C 1 193 ? 119.877 179.094 107.866 1.00 49.62  ? 193 ARG C O   1 
ATOM   10708 C CB  . ARG C 1 193 ? 122.488 179.646 107.757 1.00 51.26  ? 193 ARG C CB  1 
ATOM   10709 C CG  . ARG C 1 193 ? 124.009 179.837 107.718 1.00 44.87  ? 193 ARG C CG  1 
ATOM   10710 C CD  . ARG C 1 193 ? 124.450 180.937 106.754 1.00 48.83  ? 193 ARG C CD  1 
ATOM   10711 N NE  . ARG C 1 193 ? 125.901 180.968 106.635 1.00 52.18  ? 193 ARG C NE  1 
ATOM   10712 C CZ  . ARG C 1 193 ? 126.582 181.822 105.879 1.00 49.70  ? 193 ARG C CZ  1 
ATOM   10713 N NH1 . ARG C 1 193 ? 127.902 181.763 105.840 1.00 48.34  ? 193 ARG C NH1 1 
ATOM   10714 N NH2 . ARG C 1 193 ? 125.942 182.729 105.164 1.00 48.53  ? 193 ARG C NH2 1 
ATOM   10715 N N   . ALA C 1 194 ? 120.260 177.147 106.749 1.00 37.89  ? 194 ALA C N   1 
ATOM   10716 C CA  . ALA C 1 194 ? 119.184 176.400 107.390 1.00 32.82  ? 194 ALA C CA  1 
ATOM   10717 C C   . ALA C 1 194 ? 119.517 176.223 108.877 1.00 39.43  ? 194 ALA C C   1 
ATOM   10718 O O   . ALA C 1 194 ? 120.306 175.362 109.247 1.00 41.45  ? 194 ALA C O   1 
ATOM   10719 C CB  . ALA C 1 194 ? 119.010 175.066 106.664 1.00 30.93  ? 194 ALA C CB  1 
ATOM   10720 N N   . CYS C 1 195 ? 118.985 177.089 109.738 1.00 41.11  ? 195 CYS C N   1 
ATOM   10721 C CA  . CYS C 1 195 ? 119.447 177.295 111.116 1.00 40.11  ? 195 CYS C CA  1 
ATOM   10722 C C   . CYS C 1 195 ? 118.376 177.038 112.195 1.00 49.12  ? 195 CYS C C   1 
ATOM   10723 O O   . CYS C 1 195 ? 118.688 177.082 113.387 1.00 51.56  ? 195 CYS C O   1 
ATOM   10724 C CB  . CYS C 1 195 ? 120.015 178.718 111.213 1.00 43.03  ? 195 CYS C CB  1 
ATOM   10725 S SG  . CYS C 1 195 ? 118.740 179.949 110.824 1.00 60.88  ? 195 CYS C SG  1 
ATOM   10726 N N   . GLY C 1 196 ? 117.126 176.754 111.808 1.00 44.92  ? 196 GLY C N   1 
ATOM   10727 C CA  . GLY C 1 196 ? 116.061 176.380 112.737 1.00 41.01  ? 196 GLY C CA  1 
ATOM   10728 C C   . GLY C 1 196 ? 116.363 175.112 113.546 1.00 40.83  ? 196 GLY C C   1 
ATOM   10729 O O   . GLY C 1 196 ? 117.283 174.357 113.243 1.00 44.42  ? 196 GLY C O   1 
ATOM   10730 N N   . ARG C 1 197 ? 115.583 174.854 114.601 1.00 40.01  ? 197 ARG C N   1 
ATOM   10731 C CA  . ARG C 1 197 ? 115.850 173.793 115.581 1.00 42.34  ? 197 ARG C CA  1 
ATOM   10732 C C   . ARG C 1 197 ? 115.977 172.388 114.984 1.00 41.54  ? 197 ARG C C   1 
ATOM   10733 O O   . ARG C 1 197 ? 116.698 171.571 115.541 1.00 42.13  ? 197 ARG C O   1 
ATOM   10734 C CB  . ARG C 1 197 ? 114.771 173.856 116.679 1.00 42.99  ? 197 ARG C CB  1 
ATOM   10735 C CG  . ARG C 1 197 ? 115.038 172.978 117.909 1.00 41.25  ? 197 ARG C CG  1 
ATOM   10736 C CD  . ARG C 1 197 ? 116.385 173.310 118.552 1.00 41.36  ? 197 ARG C CD  1 
ATOM   10737 N NE  . ARG C 1 197 ? 116.608 172.570 119.799 1.00 49.80  ? 197 ARG C NE  1 
ATOM   10738 C CZ  . ARG C 1 197 ? 117.737 172.535 120.478 1.00 51.78  ? 197 ARG C CZ  1 
ATOM   10739 N NH1 . ARG C 1 197 ? 117.819 171.835 121.567 1.00 46.12  ? 197 ARG C NH1 1 
ATOM   10740 N NH2 . ARG C 1 197 ? 118.798 173.188 120.098 1.00 48.39  ? 197 ARG C NH2 1 
ATOM   10741 N N   . PHE C 1 198 ? 115.354 172.089 113.847 1.00 36.53  ? 198 PHE C N   1 
ATOM   10742 C CA  . PHE C 1 198 ? 115.541 170.812 113.152 1.00 34.34  ? 198 PHE C CA  1 
ATOM   10743 C C   . PHE C 1 198 ? 116.963 170.627 112.592 1.00 36.80  ? 198 PHE C C   1 
ATOM   10744 O O   . PHE C 1 198 ? 117.454 169.511 112.476 1.00 31.80  ? 198 PHE C O   1 
ATOM   10745 C CB  . PHE C 1 198 ? 114.517 170.720 112.018 1.00 29.26  ? 198 PHE C CB  1 
ATOM   10746 C CG  . PHE C 1 198 ? 114.651 169.444 111.222 1.00 32.98  ? 198 PHE C CG  1 
ATOM   10747 C CD1 . PHE C 1 198 ? 114.325 168.217 111.812 1.00 31.96  ? 198 PHE C CD1 1 
ATOM   10748 C CD2 . PHE C 1 198 ? 115.196 169.479 109.930 1.00 31.66  ? 198 PHE C CD2 1 
ATOM   10749 C CE1 . PHE C 1 198 ? 114.560 167.025 111.119 1.00 25.65  ? 198 PHE C CE1 1 
ATOM   10750 C CE2 . PHE C 1 198 ? 115.422 168.284 109.229 1.00 28.53  ? 198 PHE C CE2 1 
ATOM   10751 C CZ  . PHE C 1 198 ? 115.105 167.060 109.819 1.00 31.14  ? 198 PHE C CZ  1 
ATOM   10752 N N   . PHE C 1 199 ? 117.643 171.716 112.249 1.00 39.37  ? 199 PHE C N   1 
ATOM   10753 C CA  . PHE C 1 199 ? 118.969 171.696 111.640 1.00 28.27  ? 199 PHE C CA  1 
ATOM   10754 C C   . PHE C 1 199 ? 120.117 171.830 112.642 1.00 34.31  ? 199 PHE C C   1 
ATOM   10755 O O   . PHE C 1 199 ? 121.278 171.732 112.261 1.00 38.75  ? 199 PHE C O   1 
ATOM   10756 C CB  . PHE C 1 199 ? 119.017 172.811 110.604 1.00 24.88  ? 199 PHE C CB  1 
ATOM   10757 C CG  . PHE C 1 199 ? 117.944 172.684 109.559 1.00 30.56  ? 199 PHE C CG  1 
ATOM   10758 C CD1 . PHE C 1 199 ? 117.987 171.619 108.649 1.00 31.32  ? 199 PHE C CD1 1 
ATOM   10759 C CD2 . PHE C 1 199 ? 116.896 173.616 109.500 1.00 32.22  ? 199 PHE C CD2 1 
ATOM   10760 C CE1 . PHE C 1 199 ? 117.006 171.504 107.651 1.00 31.58  ? 199 PHE C CE1 1 
ATOM   10761 C CE2 . PHE C 1 199 ? 115.922 173.495 108.504 1.00 30.84  ? 199 PHE C CE2 1 
ATOM   10762 C CZ  . PHE C 1 199 ? 115.975 172.446 107.581 1.00 29.86  ? 199 PHE C CZ  1 
ATOM   10763 N N   . GLN C 1 200 ? 119.821 172.069 113.914 1.00 38.32  ? 200 GLN C N   1 
ATOM   10764 C CA  . GLN C 1 200 ? 120.792 172.121 115.002 1.00 33.63  ? 200 GLN C CA  1 
ATOM   10765 C C   . GLN C 1 200 ? 121.128 170.711 115.501 1.00 38.74  ? 200 GLN C C   1 
ATOM   10766 O O   . GLN C 1 200 ? 120.326 169.793 115.375 1.00 40.13  ? 200 GLN C O   1 
ATOM   10767 C CB  . GLN C 1 200 ? 120.237 173.000 116.131 1.00 36.97  ? 200 GLN C CB  1 
ATOM   10768 C CG  . GLN C 1 200 ? 120.068 174.465 115.696 1.00 37.38  ? 200 GLN C CG  1 
ATOM   10769 C CD  . GLN C 1 200 ? 119.276 175.308 116.687 1.00 41.48  ? 200 GLN C CD  1 
ATOM   10770 O OE1 . GLN C 1 200 ? 119.089 174.964 117.847 1.00 44.86  ? 200 GLN C OE1 1 
ATOM   10771 N NE2 . GLN C 1 200 ? 118.749 176.432 116.260 1.00 38.94  ? 200 GLN C NE2 1 
ATOM   10772 N N   . LYS C 1 201 ? 122.300 170.516 116.111 1.00 42.97  ? 201 LYS C N   1 
ATOM   10773 C CA  . LYS C 1 201 ? 122.667 169.252 116.760 1.00 40.51  ? 201 LYS C CA  1 
ATOM   10774 C C   . LYS C 1 201 ? 122.127 169.226 118.196 1.00 46.35  ? 201 LYS C C   1 
ATOM   10775 O O   . LYS C 1 201 ? 122.463 170.088 119.001 1.00 50.81  ? 201 LYS C O   1 
ATOM   10776 C CB  . LYS C 1 201 ? 124.191 169.081 116.677 1.00 45.47  ? 201 LYS C CB  1 
ATOM   10777 C CG  . LYS C 1 201 ? 124.729 167.754 117.224 1.00 47.23  ? 201 LYS C CG  1 
ATOM   10778 C CD  . LYS C 1 201 ? 124.190 166.514 116.509 1.00 50.49  ? 201 LYS C CD  1 
ATOM   10779 C CE  . LYS C 1 201 ? 124.879 165.268 117.065 1.00 52.40  ? 201 LYS C CE  1 
ATOM   10780 N NZ  . LYS C 1 201 ? 124.369 164.027 116.454 1.00 51.61  ? 201 LYS C NZ  1 
ATOM   10781 N N   . HIS C 1 202 ? 121.289 168.244 118.521 1.00 42.54  ? 202 HIS C N   1 
ATOM   10782 C CA  . HIS C 1 202 ? 120.731 167.983 119.854 1.00 42.16  ? 202 HIS C CA  1 
ATOM   10783 C C   . HIS C 1 202 ? 120.245 166.535 119.946 1.00 46.50  ? 202 HIS C C   1 
ATOM   10784 O O   . HIS C 1 202 ? 120.293 165.797 118.962 1.00 48.39  ? 202 HIS C O   1 
ATOM   10785 C CB  . HIS C 1 202 ? 119.603 168.979 120.159 1.00 42.71  ? 202 HIS C CB  1 
ATOM   10786 C CG  . HIS C 1 202 ? 118.556 169.044 119.098 1.00 45.17  ? 202 HIS C CG  1 
ATOM   10787 N ND1 . HIS C 1 202 ? 117.539 168.113 119.006 1.00 47.80  ? 202 HIS C ND1 1 
ATOM   10788 C CD2 . HIS C 1 202 ? 118.361 169.919 118.089 1.00 44.55  ? 202 HIS C CD2 1 
ATOM   10789 C CE1 . HIS C 1 202 ? 116.764 168.412 117.984 1.00 43.22  ? 202 HIS C CE1 1 
ATOM   10790 N NE2 . HIS C 1 202 ? 117.247 169.518 117.405 1.00 39.99  ? 202 HIS C NE2 1 
ATOM   10791 N N   . GLN C 1 203 ? 119.798 166.102 121.133 1.00 57.48  ? 203 GLN C N   1 
ATOM   10792 C CA  . GLN C 1 203 ? 119.421 164.668 121.347 1.00 57.27  ? 203 GLN C CA  1 
ATOM   10793 C C   . GLN C 1 203 ? 118.065 164.338 120.706 1.00 56.93  ? 203 GLN C C   1 
ATOM   10794 O O   . GLN C 1 203 ? 117.787 163.137 120.526 1.00 56.55  ? 203 GLN C O   1 
ATOM   10795 C CB  . GLN C 1 203 ? 119.449 164.370 122.851 1.00 54.65  ? 203 GLN C CB  1 
ATOM   10796 C CG  . GLN C 1 203 ? 120.868 164.428 123.440 1.00 55.07  ? 203 GLN C CG  1 
ATOM   10797 C CD  . GLN C 1 203 ? 120.884 164.115 124.916 1.00 60.45  ? 203 GLN C CD  1 
ATOM   10798 O OE1 . GLN C 1 203 ? 121.927 164.143 125.566 1.00 61.84  ? 203 GLN C OE1 1 
ATOM   10799 N NE2 . GLN C 1 203 ? 119.716 163.815 125.460 1.00 58.07  ? 203 GLN C NE2 1 
ATOM   10800 N N   . GLY C 1 204 ? 117.261 165.348 120.375 1.00 49.41  ? 204 GLY C N   1 
ATOM   10801 C CA  . GLY C 1 204 ? 115.947 165.192 119.756 1.00 46.63  ? 204 GLY C CA  1 
ATOM   10802 C C   . GLY C 1 204 ? 115.980 164.897 118.257 1.00 45.77  ? 204 GLY C C   1 
ATOM   10803 O O   . GLY C 1 204 ? 116.979 164.444 117.701 1.00 52.01  ? 204 GLY C O   1 
ATOM   10804 N N   . THR C 1 205 ? 114.858 165.126 117.584 1.00 45.69  ? 205 THR C N   1 
ATOM   10805 C CA  . THR C 1 205 ? 114.697 164.863 116.148 1.00 46.05  ? 205 THR C CA  1 
ATOM   10806 C C   . THR C 1 205 ? 115.301 166.001 115.320 1.00 42.92  ? 205 THR C C   1 
ATOM   10807 O O   . THR C 1 205 ? 114.769 167.109 115.261 1.00 43.37  ? 205 THR C O   1 
ATOM   10808 C CB  . THR C 1 205 ? 113.224 164.554 115.805 1.00 46.43  ? 205 THR C CB  1 
ATOM   10809 O OG1 . THR C 1 205 ? 112.340 165.515 116.331 1.00 53.17  ? 205 THR C OG1 1 
ATOM   10810 C CG2 . THR C 1 205 ? 112.822 163.217 116.406 1.00 45.87  ? 205 THR C CG2 1 
ATOM   10811 N N   . CYS C 1 206 ? 116.455 165.746 114.701 1.00 36.44  ? 206 CYS C N   1 
ATOM   10812 C CA  . CYS C 1 206 ? 117.217 166.736 113.946 1.00 31.21  ? 206 CYS C CA  1 
ATOM   10813 C C   . CYS C 1 206 ? 118.119 166.122 112.869 1.00 28.99  ? 206 CYS C C   1 
ATOM   10814 O O   . CYS C 1 206 ? 118.436 164.933 112.881 1.00 33.97  ? 206 CYS C O   1 
ATOM   10815 C CB  . CYS C 1 206 ? 118.033 167.598 114.918 1.00 34.69  ? 206 CYS C CB  1 
ATOM   10816 S SG  . CYS C 1 206 ? 119.464 166.742 115.618 1.00 30.25  ? 206 CYS C SG  1 
ATOM   10817 N N   . PHE C 1 207 ? 118.578 166.971 111.958 1.00 26.59  ? 207 PHE C N   1 
ATOM   10818 C CA  . PHE C 1 207 ? 119.564 166.673 110.929 1.00 22.30  ? 207 PHE C CA  1 
ATOM   10819 C C   . PHE C 1 207 ? 120.564 167.829 110.850 1.00 22.78  ? 207 PHE C C   1 
ATOM   10820 O O   . PHE C 1 207 ? 120.385 168.775 110.092 1.00 30.79  ? 207 PHE C O   1 
ATOM   10821 C CB  . PHE C 1 207 ? 118.828 166.411 109.608 1.00 24.89  ? 207 PHE C CB  1 
ATOM   10822 C CG  . PHE C 1 207 ? 119.671 166.168 108.370 1.00 23.88  ? 207 PHE C CG  1 
ATOM   10823 C CD1 . PHE C 1 207 ? 120.939 165.563 108.424 1.00 26.38  ? 207 PHE C CD1 1 
ATOM   10824 C CD2 . PHE C 1 207 ? 119.129 166.501 107.119 1.00 30.94  ? 207 PHE C CD2 1 
ATOM   10825 C CE1 . PHE C 1 207 ? 121.649 165.304 107.241 1.00 21.95  ? 207 PHE C CE1 1 
ATOM   10826 C CE2 . PHE C 1 207 ? 119.840 166.251 105.936 1.00 24.61  ? 207 PHE C CE2 1 
ATOM   10827 C CZ  . PHE C 1 207 ? 121.102 165.643 105.998 1.00 28.13  ? 207 PHE C CZ  1 
ATOM   10828 N N   . TYR C 1 208 ? 121.619 167.765 111.660 1.00 22.04  ? 208 TYR C N   1 
ATOM   10829 C CA  . TYR C 1 208 ? 122.771 168.649 111.518 1.00 28.34  ? 208 TYR C CA  1 
ATOM   10830 C C   . TYR C 1 208 ? 123.686 168.189 110.375 1.00 30.84  ? 208 TYR C C   1 
ATOM   10831 O O   . TYR C 1 208 ? 124.127 167.046 110.340 1.00 34.14  ? 208 TYR C O   1 
ATOM   10832 C CB  . TYR C 1 208 ? 123.532 168.760 112.847 1.00 24.31  ? 208 TYR C CB  1 
ATOM   10833 C CG  . TYR C 1 208 ? 124.697 169.723 112.776 1.00 24.46  ? 208 TYR C CG  1 
ATOM   10834 C CD1 . TYR C 1 208 ? 124.472 171.102 112.892 1.00 27.59  ? 208 TYR C CD1 1 
ATOM   10835 C CD2 . TYR C 1 208 ? 125.990 169.252 112.487 1.00 28.51  ? 208 TYR C CD2 1 
ATOM   10836 C CE1 . TYR C 1 208 ? 125.519 172.018 112.695 1.00 32.19  ? 208 TYR C CE1 1 
ATOM   10837 C CE2 . TYR C 1 208 ? 127.036 170.167 112.276 1.00 26.46  ? 208 TYR C CE2 1 
ATOM   10838 C CZ  . TYR C 1 208 ? 126.803 171.549 112.381 1.00 32.07  ? 208 TYR C CZ  1 
ATOM   10839 O OH  . TYR C 1 208 ? 127.808 172.422 112.137 1.00 37.95  ? 208 TYR C OH  1 
ATOM   10840 N N   . PHE C 1 209 ? 124.029 169.101 109.470 1.00 27.39  ? 209 PHE C N   1 
ATOM   10841 C CA  . PHE C 1 209 ? 124.924 168.886 108.329 1.00 29.65  ? 209 PHE C CA  1 
ATOM   10842 C C   . PHE C 1 209 ? 125.823 170.110 108.110 1.00 27.13  ? 209 PHE C C   1 
ATOM   10843 O O   . PHE C 1 209 ? 126.294 170.374 107.011 1.00 38.68  ? 209 PHE C O   1 
ATOM   10844 C CB  . PHE C 1 209 ? 124.084 168.572 107.077 1.00 25.78  ? 209 PHE C CB  1 
ATOM   10845 C CG  . PHE C 1 209 ? 122.998 169.587 106.738 1.00 23.16  ? 209 PHE C CG  1 
ATOM   10846 C CD1 . PHE C 1 209 ? 123.303 170.819 106.126 1.00 24.16  ? 209 PHE C CD1 1 
ATOM   10847 C CD2 . PHE C 1 209 ? 121.659 169.288 107.036 1.00 22.88  ? 209 PHE C CD2 1 
ATOM   10848 C CE1 . PHE C 1 209 ? 122.285 171.751 105.853 1.00 27.74  ? 209 PHE C CE1 1 
ATOM   10849 C CE2 . PHE C 1 209 ? 120.640 170.198 106.721 1.00 29.89  ? 209 PHE C CE2 1 
ATOM   10850 C CZ  . PHE C 1 209 ? 120.951 171.440 106.148 1.00 27.63  ? 209 PHE C CZ  1 
ATOM   10851 N N   . GLY C 1 210 ? 126.046 170.903 109.150 1.00 23.23  ? 210 GLY C N   1 
ATOM   10852 C CA  . GLY C 1 210 ? 126.305 172.321 108.968 1.00 27.90  ? 210 GLY C CA  1 
ATOM   10853 C C   . GLY C 1 210 ? 124.952 172.992 108.746 1.00 41.48  ? 210 GLY C C   1 
ATOM   10854 O O   . GLY C 1 210 ? 123.916 172.438 109.117 1.00 52.52  ? 210 GLY C O   1 
ATOM   10855 N N   . GLU C 1 211 ? 124.920 174.152 108.102 1.00 36.84  ? 211 GLU C N   1 
ATOM   10856 C CA  . GLU C 1 211 ? 123.647 174.819 107.782 1.00 31.99  ? 211 GLU C CA  1 
ATOM   10857 C C   . GLU C 1 211 ? 123.552 175.237 106.311 1.00 33.69  ? 211 GLU C C   1 
ATOM   10858 O O   . GLU C 1 211 ? 122.513 175.683 105.844 1.00 35.37  ? 211 GLU C O   1 
ATOM   10859 C CB  . GLU C 1 211 ? 123.463 176.022 108.715 1.00 32.02  ? 211 GLU C CB  1 
ATOM   10860 C CG  . GLU C 1 211 ? 123.410 175.600 110.191 1.00 30.49  ? 211 GLU C CG  1 
ATOM   10861 C CD  . GLU C 1 211 ? 123.299 176.787 111.151 1.00 40.22  ? 211 GLU C CD  1 
ATOM   10862 O OE1 . GLU C 1 211 ? 123.623 177.937 110.774 1.00 43.91  ? 211 GLU C OE1 1 
ATOM   10863 O OE2 . GLU C 1 211 ? 122.951 176.564 112.327 1.00 42.80  ? 211 GLU C OE2 1 
ATOM   10864 N N   . LEU C 1 212 ? 124.648 175.108 105.563 1.00 38.64  ? 212 LEU C N   1 
ATOM   10865 C CA  . LEU C 1 212 ? 124.642 175.678 104.185 1.00 33.70  ? 212 LEU C CA  1 
ATOM   10866 C C   . LEU C 1 212 ? 124.569 174.600 103.102 1.00 33.76  ? 212 LEU C C   1 
ATOM   10867 O O   . LEU C 1 212 ? 124.929 173.439 103.382 1.00 40.09  ? 212 LEU C O   1 
ATOM   10868 C CB  . LEU C 1 212 ? 125.897 176.544 104.012 1.00 38.55  ? 212 LEU C CB  1 
ATOM   10869 C CG  . LEU C 1 212 ? 125.979 177.767 104.923 1.00 41.52  ? 212 LEU C CG  1 
ATOM   10870 C CD1 . LEU C 1 212 ? 126.176 177.349 106.374 1.00 40.34  ? 212 LEU C CD1 1 
ATOM   10871 C CD2 . LEU C 1 212 ? 127.100 178.696 104.484 1.00 38.83  ? 212 LEU C CD2 1 
ATOM   10872 N N   . PRO C 1 213 ? 124.120 174.955 101.878 1.00 36.26  ? 213 PRO C N   1 
ATOM   10873 C CA  . PRO C 1 213 ? 124.066 174.006 100.765 1.00 37.61  ? 213 PRO C CA  1 
ATOM   10874 C C   . PRO C 1 213 ? 125.374 173.217 100.623 1.00 37.40  ? 213 PRO C C   1 
ATOM   10875 O O   . PRO C 1 213 ? 125.305 172.002 100.569 1.00 35.74  ? 213 PRO C O   1 
ATOM   10876 C CB  . PRO C 1 213 ? 123.882 174.927 99.551  1.00 40.37  ? 213 PRO C CB  1 
ATOM   10877 C CG  . PRO C 1 213 ? 123.093 176.094 100.099 1.00 32.93  ? 213 PRO C CG  1 
ATOM   10878 C CD  . PRO C 1 213 ? 123.620 176.281 101.506 1.00 33.68  ? 213 PRO C CD  1 
ATOM   10879 N N   . LEU C 1 214 ? 126.519 173.905 100.562 1.00 34.17  ? 214 LEU C N   1 
ATOM   10880 C CA  . LEU C 1 214 ? 127.759 173.159 100.333 1.00 32.87  ? 214 LEU C CA  1 
ATOM   10881 C C   . LEU C 1 214 ? 128.011 172.092 101.406 1.00 26.47  ? 214 LEU C C   1 
ATOM   10882 O O   . LEU C 1 214 ? 128.408 170.974 101.090 1.00 32.33  ? 214 LEU C O   1 
ATOM   10883 C CB  . LEU C 1 214 ? 128.935 174.142 100.229 1.00 38.33  ? 214 LEU C CB  1 
ATOM   10884 C CG  . LEU C 1 214 ? 130.284 173.454 99.957  1.00 33.63  ? 214 LEU C CG  1 
ATOM   10885 C CD1 . LEU C 1 214 ? 130.324 172.840 98.566  1.00 34.10  ? 214 LEU C CD1 1 
ATOM   10886 C CD2 . LEU C 1 214 ? 131.426 174.446 100.079 1.00 32.84  ? 214 LEU C CD2 1 
ATOM   10887 N N   . SER C 1 215 ? 127.753 172.416 102.670 1.00 20.77  ? 215 SER C N   1 
ATOM   10888 C CA  . SER C 1 215 ? 127.898 171.462 103.766 1.00 14.71  ? 215 SER C CA  1 
ATOM   10889 C C   . SER C 1 215 ? 126.871 170.340 103.685 1.00 22.18  ? 215 SER C C   1 
ATOM   10890 O O   . SER C 1 215 ? 127.234 169.188 103.884 1.00 23.95  ? 215 SER C O   1 
ATOM   10891 C CB  . SER C 1 215 ? 127.830 172.153 105.121 1.00 26.47  ? 215 SER C CB  1 
ATOM   10892 O OG  . SER C 1 215 ? 128.686 173.277 105.151 1.00 34.27  ? 215 SER C OG  1 
ATOM   10893 N N   . LEU C 1 216 ? 125.632 170.628 103.279 1.00 36.54  ? 216 LEU C N   1 
ATOM   10894 C CA  . LEU C 1 216 ? 124.642 169.613 102.937 1.00 23.43  ? 216 LEU C CA  1 
ATOM   10895 C C   . LEU C 1 216 ? 125.162 168.704 101.821 1.00 28.15  ? 216 LEU C C   1 
ATOM   10896 O O   . LEU C 1 216 ? 125.276 167.508 102.039 1.00 38.38  ? 216 LEU C O   1 
ATOM   10897 C CB  . LEU C 1 216 ? 123.318 170.301 102.578 1.00 26.52  ? 216 LEU C CB  1 
ATOM   10898 C CG  . LEU C 1 216 ? 122.156 169.351 102.246 1.00 27.29  ? 216 LEU C CG  1 
ATOM   10899 C CD1 . LEU C 1 216 ? 121.771 168.416 103.387 1.00 23.30  ? 216 LEU C CD1 1 
ATOM   10900 C CD2 . LEU C 1 216 ? 120.946 170.200 101.891 1.00 25.38  ? 216 LEU C CD2 1 
ATOM   10901 N N   . ALA C 1 217 ? 125.563 169.249 100.669 1.00 26.06  ? 217 ALA C N   1 
ATOM   10902 C CA  . ALA C 1 217 ? 126.061 168.458 99.546  1.00 22.88  ? 217 ALA C CA  1 
ATOM   10903 C C   . ALA C 1 217 ? 127.271 167.573 99.907  1.00 31.61  ? 217 ALA C C   1 
ATOM   10904 O O   . ALA C 1 217 ? 127.382 166.442 99.437  1.00 31.82  ? 217 ALA C O   1 
ATOM   10905 C CB  . ALA C 1 217 ? 126.393 169.415 98.398  1.00 26.51  ? 217 ALA C CB  1 
ATOM   10906 N N   . ALA C 1 218 ? 128.170 168.054 100.771 1.00 32.97  ? 218 ALA C N   1 
ATOM   10907 C CA  . ALA C 1 218 ? 129.274 167.269 101.303 1.00 24.68  ? 218 ALA C CA  1 
ATOM   10908 C C   . ALA C 1 218 ? 128.800 166.177 102.276 1.00 24.51  ? 218 ALA C C   1 
ATOM   10909 O O   . ALA C 1 218 ? 129.213 165.026 102.159 1.00 29.46  ? 218 ALA C O   1 
ATOM   10910 C CB  . ALA C 1 218 ? 130.264 168.220 101.966 1.00 27.04  ? 218 ALA C CB  1 
ATOM   10911 N N   . CYS C 1 219 ? 127.906 166.496 103.210 1.00 28.54  ? 219 CYS C N   1 
ATOM   10912 C CA  . CYS C 1 219 ? 127.410 165.540 104.200 1.00 28.74  ? 219 CYS C CA  1 
ATOM   10913 C C   . CYS C 1 219 ? 126.521 164.441 103.601 1.00 33.23  ? 219 CYS C C   1 
ATOM   10914 O O   . CYS C 1 219 ? 126.463 163.335 104.130 1.00 32.12  ? 219 CYS C O   1 
ATOM   10915 C CB  . CYS C 1 219 ? 126.693 166.279 105.339 1.00 32.38  ? 219 CYS C CB  1 
ATOM   10916 S SG  . CYS C 1 219 ? 127.816 167.388 106.259 1.00 36.50  ? 219 CYS C SG  1 
ATOM   10917 N N   . THR C 1 220 ? 125.971 164.717 102.411 1.00 40.44  ? 220 THR C N   1 
ATOM   10918 C CA  . THR C 1 220 ? 125.148 163.708 101.691 1.00 33.81  ? 220 THR C CA  1 
ATOM   10919 C C   . THR C 1 220 ? 126.020 162.941 100.686 1.00 38.69  ? 220 THR C C   1 
ATOM   10920 O O   . THR C 1 220 ? 125.501 161.960 100.122 1.00 48.03  ? 220 THR C O   1 
ATOM   10921 C CB  . THR C 1 220 ? 123.962 164.375 100.982 1.00 38.80  ? 220 THR C CB  1 
ATOM   10922 O OG1 . THR C 1 220 ? 124.489 165.322 100.052 1.00 43.27  ? 220 THR C OG1 1 
ATOM   10923 C CG2 . THR C 1 220 ? 123.018 165.068 101.940 1.00 37.39  ? 220 THR C CG2 1 
ATOM   10924 N N   . LYS C 1 221 ? 127.259 163.390 100.439 1.00 41.73  ? 221 LYS C N   1 
ATOM   10925 C CA  . LYS C 1 221 ? 128.225 162.676 99.541  1.00 40.12  ? 221 LYS C CA  1 
ATOM   10926 C C   . LYS C 1 221 ? 127.930 162.965 98.057  1.00 43.09  ? 221 LYS C C   1 
ATOM   10927 O O   . LYS C 1 221 ? 128.294 162.126 97.209  1.00 43.36  ? 221 LYS C O   1 
ATOM   10928 C CB  . LYS C 1 221 ? 128.286 161.180 99.882  1.00 37.84  ? 221 LYS C CB  1 
ATOM   10929 C CG  . LYS C 1 221 ? 127.447 160.238 99.027  1.00 44.63  ? 221 LYS C CG  1 
ATOM   10930 C CD  . LYS C 1 221 ? 127.673 158.780 99.358  1.00 45.46  ? 221 LYS C CD  1 
ATOM   10931 C CE  . LYS C 1 221 ? 127.140 157.841 98.297  1.00 49.55  ? 221 LYS C CE  1 
ATOM   10932 N NZ  . LYS C 1 221 ? 127.324 156.421 98.679  1.00 50.93  ? 221 LYS C NZ  1 
ATOM   10933 N N   . GLN C 1 222 ? 127.350 164.126 97.744  1.00 44.99  ? 222 GLN C N   1 
ATOM   10934 C CA  . GLN C 1 222 ? 127.072 164.514 96.360  1.00 43.83  ? 222 GLN C CA  1 
ATOM   10935 C C   . GLN C 1 222 ? 128.258 165.269 95.760  1.00 40.13  ? 222 GLN C C   1 
ATOM   10936 O O   . GLN C 1 222 ? 128.235 166.488 95.612  1.00 41.93  ? 222 GLN C O   1 
ATOM   10937 C CB  . GLN C 1 222 ? 125.776 165.323 96.295  1.00 45.16  ? 222 GLN C CB  1 
ATOM   10938 C CG  . GLN C 1 222 ? 124.580 164.416 96.579  1.00 38.59  ? 222 GLN C CG  1 
ATOM   10939 C CD  . GLN C 1 222 ? 123.354 165.206 96.976  1.00 40.34  ? 222 GLN C CD  1 
ATOM   10940 O OE1 . GLN C 1 222 ? 122.801 165.024 98.042  1.00 47.11  ? 222 GLN C OE1 1 
ATOM   10941 N NE2 . GLN C 1 222 ? 122.886 166.116 96.164  1.00 45.84  ? 222 GLN C NE2 1 
ATOM   10942 N N   . TRP C 1 223 ? 129.323 164.544 95.436  1.00 41.89  ? 223 TRP C N   1 
ATOM   10943 C CA  . TRP C 1 223 ? 130.582 165.140 94.989  1.00 50.21  ? 223 TRP C CA  1 
ATOM   10944 C C   . TRP C 1 223 ? 130.453 165.951 93.688  1.00 50.27  ? 223 TRP C C   1 
ATOM   10945 O O   . TRP C 1 223 ? 131.116 166.966 93.521  1.00 50.28  ? 223 TRP C O   1 
ATOM   10946 C CB  . TRP C 1 223 ? 131.623 164.021 94.881  1.00 47.55  ? 223 TRP C CB  1 
ATOM   10947 C CG  . TRP C 1 223 ? 133.005 164.499 94.590  1.00 48.26  ? 223 TRP C CG  1 
ATOM   10948 C CD1 . TRP C 1 223 ? 133.754 164.162 93.516  1.00 50.98  ? 223 TRP C CD1 1 
ATOM   10949 C CD2 . TRP C 1 223 ? 133.819 165.417 95.377  1.00 51.71  ? 223 TRP C CD2 1 
ATOM   10950 N NE1 . TRP C 1 223 ? 134.970 164.814 93.583  1.00 52.41  ? 223 TRP C NE1 1 
ATOM   10951 C CE2 . TRP C 1 223 ? 135.058 165.614 94.701  1.00 53.70  ? 223 TRP C CE2 1 
ATOM   10952 C CE3 . TRP C 1 223 ? 133.628 166.119 96.585  1.00 48.93  ? 223 TRP C CE3 1 
ATOM   10953 C CZ2 . TRP C 1 223 ? 136.043 166.477 95.188  1.00 48.71  ? 223 TRP C CZ2 1 
ATOM   10954 C CZ3 . TRP C 1 223 ? 134.600 167.010 97.071  1.00 44.18  ? 223 TRP C CZ3 1 
ATOM   10955 C CH2 . TRP C 1 223 ? 135.786 167.215 96.353  1.00 50.56  ? 223 TRP C CH2 1 
ATOM   10956 N N   . ASP C 1 224 ? 129.537 165.561 92.801  1.00 50.09  ? 224 ASP C N   1 
ATOM   10957 C CA  . ASP C 1 224 ? 129.184 166.310 91.552  1.00 49.31  ? 224 ASP C CA  1 
ATOM   10958 C C   . ASP C 1 224 ? 128.371 167.583 91.856  1.00 49.15  ? 224 ASP C C   1 
ATOM   10959 O O   . ASP C 1 224 ? 128.485 168.523 91.046  1.00 48.67  ? 224 ASP C O   1 
ATOM   10960 C CB  . ASP C 1 224 ? 128.421 165.416 90.571  1.00 51.64  ? 224 ASP C CB  1 
ATOM   10961 C CG  . ASP C 1 224 ? 127.086 164.934 91.114  1.00 56.26  ? 224 ASP C CG  1 
ATOM   10962 O OD1 . ASP C 1 224 ? 126.824 165.167 92.311  1.00 54.71  ? 224 ASP C OD1 1 
ATOM   10963 O OD2 . ASP C 1 224 ? 126.320 164.335 90.335  1.00 57.67  ? 224 ASP C OD2 1 
ATOM   10964 N N   . VAL C 1 225 ? 127.602 167.655 92.946  1.00 48.37  ? 225 VAL C N   1 
ATOM   10965 C CA  . VAL C 1 225 ? 126.984 168.905 93.407  1.00 45.62  ? 225 VAL C CA  1 
ATOM   10966 C C   . VAL C 1 225 ? 128.012 169.799 94.101  1.00 48.98  ? 225 VAL C C   1 
ATOM   10967 O O   . VAL C 1 225 ? 128.012 171.004 93.876  1.00 48.56  ? 225 VAL C O   1 
ATOM   10968 C CB  . VAL C 1 225 ? 125.778 168.635 94.325  1.00 46.89  ? 225 VAL C CB  1 
ATOM   10969 C CG1 . VAL C 1 225 ? 125.185 169.924 94.888  1.00 46.82  ? 225 VAL C CG1 1 
ATOM   10970 C CG2 . VAL C 1 225 ? 124.655 167.917 93.573  1.00 45.09  ? 225 VAL C CG2 1 
ATOM   10971 N N   . VAL C 1 226 ? 128.918 169.230 94.901  1.00 47.35  ? 226 VAL C N   1 
ATOM   10972 C CA  . VAL C 1 226 ? 130.010 169.963 95.554  1.00 46.28  ? 226 VAL C CA  1 
ATOM   10973 C C   . VAL C 1 226 ? 130.885 170.692 94.532  1.00 45.28  ? 226 VAL C C   1 
ATOM   10974 O O   . VAL C 1 226 ? 131.058 171.904 94.639  1.00 46.38  ? 226 VAL C O   1 
ATOM   10975 C CB  . VAL C 1 226 ? 130.840 169.014 96.440  1.00 44.68  ? 226 VAL C CB  1 
ATOM   10976 C CG1 . VAL C 1 226 ? 132.165 169.614 96.902  1.00 47.51  ? 226 VAL C CG1 1 
ATOM   10977 C CG2 . VAL C 1 226 ? 130.060 168.610 97.688  1.00 41.76  ? 226 VAL C CG2 1 
ATOM   10978 N N   . THR C 1 227 ? 131.392 169.991 93.512  1.00 51.29  ? 227 THR C N   1 
ATOM   10979 C CA  . THR C 1 227 ? 132.204 170.639 92.474  1.00 51.12  ? 227 THR C CA  1 
ATOM   10980 C C   . THR C 1 227 ? 131.410 171.672 91.685  1.00 50.49  ? 227 THR C C   1 
ATOM   10981 O O   . THR C 1 227 ? 131.939 172.740 91.410  1.00 54.87  ? 227 THR C O   1 
ATOM   10982 C CB  . THR C 1 227 ? 132.858 169.640 91.514  1.00 53.14  ? 227 THR C CB  1 
ATOM   10983 O OG1 . THR C 1 227 ? 131.892 168.845 90.884  1.00 55.88  ? 227 THR C OG1 1 
ATOM   10984 C CG2 . THR C 1 227 ? 133.844 168.735 92.236  1.00 51.72  ? 227 THR C CG2 1 
ATOM   10985 N N   . TYR C 1 228 ? 130.133 171.441 91.376  1.00 48.60  ? 228 TYR C N   1 
ATOM   10986 C CA  . TYR C 1 228 ? 129.290 172.461 90.757  1.00 46.01  ? 228 TYR C CA  1 
ATOM   10987 C C   . TYR C 1 228 ? 129.113 173.700 91.644  1.00 46.16  ? 228 TYR C C   1 
ATOM   10988 O O   . TYR C 1 228 ? 129.363 174.822 91.203  1.00 49.22  ? 228 TYR C O   1 
ATOM   10989 C CB  . TYR C 1 228 ? 127.902 171.944 90.375  1.00 50.00  ? 228 TYR C CB  1 
ATOM   10990 C CG  . TYR C 1 228 ? 127.006 173.050 89.882  1.00 54.69  ? 228 TYR C CG  1 
ATOM   10991 C CD1 . TYR C 1 228 ? 127.070 173.498 88.573  1.00 52.37  ? 228 TYR C CD1 1 
ATOM   10992 C CD2 . TYR C 1 228 ? 126.143 173.703 90.745  1.00 50.90  ? 228 TYR C CD2 1 
ATOM   10993 C CE1 . TYR C 1 228 ? 126.277 174.542 88.127  1.00 48.91  ? 228 TYR C CE1 1 
ATOM   10994 C CE2 . TYR C 1 228 ? 125.342 174.746 90.317  1.00 45.62  ? 228 TYR C CE2 1 
ATOM   10995 C CZ  . TYR C 1 228 ? 125.410 175.168 89.004  1.00 51.33  ? 228 TYR C CZ  1 
ATOM   10996 O OH  . TYR C 1 228 ? 124.625 176.197 88.581  1.00 56.03  ? 228 TYR C OH  1 
ATOM   10997 N N   . LEU C 1 229 ? 128.727 173.538 92.909  1.00 50.38  ? 229 LEU C N   1 
ATOM   10998 C CA  . LEU C 1 229 ? 128.549 174.662 93.827  1.00 49.19  ? 229 LEU C CA  1 
ATOM   10999 C C   . LEU C 1 229 ? 129.844 175.459 93.999  1.00 54.21  ? 229 LEU C C   1 
ATOM   11000 O O   . LEU C 1 229 ? 129.780 176.677 94.071  1.00 54.88  ? 229 LEU C O   1 
ATOM   11001 C CB  . LEU C 1 229 ? 128.044 174.174 95.193  1.00 48.81  ? 229 LEU C CB  1 
ATOM   11002 C CG  . LEU C 1 229 ? 126.594 173.662 95.234  1.00 52.30  ? 229 LEU C CG  1 
ATOM   11003 C CD1 . LEU C 1 229 ? 126.267 173.247 96.665  1.00 46.38  ? 229 LEU C CD1 1 
ATOM   11004 C CD2 . LEU C 1 229 ? 125.568 174.703 94.785  1.00 51.42  ? 229 LEU C CD2 1 
ATOM   11005 N N   . LEU C 1 230 ? 131.002 174.802 94.029  1.00 52.98  ? 230 LEU C N   1 
ATOM   11006 C CA  . LEU C 1 230 ? 132.310 175.445 94.114  1.00 50.07  ? 230 LEU C CA  1 
ATOM   11007 C C   . LEU C 1 230 ? 132.754 176.128 92.807  1.00 53.51  ? 230 LEU C C   1 
ATOM   11008 O O   . LEU C 1 230 ? 133.252 177.250 92.848  1.00 56.90  ? 230 LEU C O   1 
ATOM   11009 C CB  . LEU C 1 230 ? 133.332 174.383 94.545  1.00 51.46  ? 230 LEU C CB  1 
ATOM   11010 C CG  . LEU C 1 230 ? 133.215 173.922 96.008  1.00 46.94  ? 230 LEU C CG  1 
ATOM   11011 C CD1 . LEU C 1 230 ? 134.131 172.729 96.260  1.00 46.96  ? 230 LEU C CD1 1 
ATOM   11012 C CD2 . LEU C 1 230 ? 133.609 175.021 96.982  1.00 45.33  ? 230 LEU C CD2 1 
ATOM   11013 N N   . GLU C 1 231 ? 132.609 175.475 91.656  1.00 59.08  ? 231 GLU C N   1 
ATOM   11014 C CA  . GLU C 1 231 ? 133.235 175.890 90.392  1.00 57.35  ? 231 GLU C CA  1 
ATOM   11015 C C   . GLU C 1 231 ? 132.317 176.636 89.407  1.00 60.43  ? 231 GLU C C   1 
ATOM   11016 O O   . GLU C 1 231 ? 132.812 177.127 88.389  1.00 66.58  ? 231 GLU C O   1 
ATOM   11017 C CB  . GLU C 1 231 ? 133.877 174.673 89.708  1.00 58.53  ? 231 GLU C CB  1 
ATOM   11018 C CG  . GLU C 1 231 ? 134.966 174.025 90.572  1.00 60.62  ? 231 GLU C CG  1 
ATOM   11019 C CD  . GLU C 1 231 ? 135.779 172.989 89.792  1.00 61.83  ? 231 GLU C CD  1 
ATOM   11020 O OE1 . GLU C 1 231 ? 135.187 172.104 89.136  1.00 62.92  ? 231 GLU C OE1 1 
ATOM   11021 O OE2 . GLU C 1 231 ? 137.028 173.054 89.836  1.00 63.22  ? 231 GLU C OE2 1 
ATOM   11022 N N   . ASN C 1 232 ? 131.006 176.737 89.650  1.00 57.16  ? 232 ASN C N   1 
ATOM   11023 C CA  . ASN C 1 232 ? 130.097 177.439 88.738  1.00 59.33  ? 232 ASN C CA  1 
ATOM   11024 C C   . ASN C 1 232 ? 130.407 178.954 88.627  1.00 60.58  ? 232 ASN C C   1 
ATOM   11025 O O   . ASN C 1 232 ? 130.928 179.549 89.574  1.00 60.33  ? 232 ASN C O   1 
ATOM   11026 C CB  . ASN C 1 232 ? 128.631 177.192 89.137  1.00 58.36  ? 232 ASN C CB  1 
ATOM   11027 C CG  . ASN C 1 232 ? 128.169 178.060 90.289  1.00 59.93  ? 232 ASN C CG  1 
ATOM   11028 O OD1 . ASN C 1 232 ? 127.733 179.182 90.096  1.00 60.95  ? 232 ASN C OD1 1 
ATOM   11029 N ND2 . ASN C 1 232 ? 128.259 177.585 91.502  1.00 54.49  ? 232 ASN C ND2 1 
ATOM   11030 N N   . PRO C 1 233 ? 130.063 179.608 87.501  1.00 62.00  ? 233 PRO C N   1 
ATOM   11031 C CA  . PRO C 1 233 ? 130.333 181.030 87.292  1.00 61.49  ? 233 PRO C CA  1 
ATOM   11032 C C   . PRO C 1 233 ? 129.297 181.983 87.921  1.00 63.66  ? 233 PRO C C   1 
ATOM   11033 O O   . PRO C 1 233 ? 129.586 183.166 88.085  1.00 63.41  ? 233 PRO C O   1 
ATOM   11034 C CB  . PRO C 1 233 ? 130.361 181.187 85.774  1.00 60.40  ? 233 PRO C CB  1 
ATOM   11035 C CG  . PRO C 1 233 ? 129.346 180.155 85.294  1.00 61.39  ? 233 PRO C CG  1 
ATOM   11036 C CD  . PRO C 1 233 ? 129.547 179.008 86.279  1.00 59.44  ? 233 PRO C CD  1 
ATOM   11037 N N   . HIS C 1 234 ? 128.087 181.519 88.236  1.00 64.62  ? 234 HIS C N   1 
ATOM   11038 C CA  . HIS C 1 234 ? 126.949 182.366 88.632  1.00 64.80  ? 234 HIS C CA  1 
ATOM   11039 C C   . HIS C 1 234 ? 127.071 182.864 90.073  1.00 63.52  ? 234 HIS C C   1 
ATOM   11040 O O   . HIS C 1 234 ? 126.954 184.084 90.292  1.00 63.23  ? 234 HIS C O   1 
ATOM   11041 C CB  . HIS C 1 234 ? 125.637 181.593 88.435  1.00 63.55  ? 234 HIS C CB  1 
ATOM   11042 C CG  . HIS C 1 234 ? 125.777 180.402 87.548  1.00 65.40  ? 234 HIS C CG  1 
ATOM   11043 N ND1 . HIS C 1 234 ? 125.884 180.512 86.176  1.00 65.39  ? 234 HIS C ND1 1 
ATOM   11044 C CD2 . HIS C 1 234 ? 125.829 179.082 87.827  1.00 65.37  ? 234 HIS C CD2 1 
ATOM   11045 C CE1 . HIS C 1 234 ? 125.994 179.310 85.648  1.00 65.63  ? 234 HIS C CE1 1 
ATOM   11046 N NE2 . HIS C 1 234 ? 125.966 178.415 86.641  1.00 65.51  ? 234 HIS C NE2 1 
ATOM   11047 N N   . GLN C 1 235 ? 127.308 181.941 91.002  1.00 64.12  ? 235 GLN C N   1 
ATOM   11048 C CA  . GLN C 1 235 ? 127.715 182.223 92.375  1.00 62.88  ? 235 GLN C CA  1 
ATOM   11049 C C   . GLN C 1 235 ? 128.460 180.998 92.923  1.00 63.19  ? 235 GLN C C   1 
ATOM   11050 O O   . GLN C 1 235 ? 127.824 179.976 93.200  1.00 60.94  ? 235 GLN C O   1 
ATOM   11051 C CB  . GLN C 1 235 ? 126.507 182.591 93.256  1.00 59.15  ? 235 GLN C CB  1 
ATOM   11052 C CG  . GLN C 1 235 ? 126.957 182.911 94.690  1.00 61.24  ? 235 GLN C CG  1 
ATOM   11053 C CD  . GLN C 1 235 ? 125.828 183.355 95.615  1.00 64.73  ? 235 GLN C CD  1 
ATOM   11054 O OE1 . GLN C 1 235 ? 124.857 183.978 95.219  1.00 64.60  ? 235 GLN C OE1 1 
ATOM   11055 N NE2 . GLN C 1 235 ? 125.927 183.047 96.891  1.00 64.37  ? 235 GLN C NE2 1 
ATOM   11056 N N   . PRO C 1 236 ? 129.788 181.064 93.109  1.00 64.19  ? 236 PRO C N   1 
ATOM   11057 C CA  . PRO C 1 236 ? 130.533 179.978 93.725  1.00 58.92  ? 236 PRO C CA  1 
ATOM   11058 C C   . PRO C 1 236 ? 130.323 179.951 95.244  1.00 57.63  ? 236 PRO C C   1 
ATOM   11059 O O   . PRO C 1 236 ? 130.330 180.988 95.910  1.00 57.68  ? 236 PRO C O   1 
ATOM   11060 C CB  . PRO C 1 236 ? 131.988 180.230 93.333  1.00 57.66  ? 236 PRO C CB  1 
ATOM   11061 C CG  . PRO C 1 236 ? 132.063 181.749 93.214  1.00 59.47  ? 236 PRO C CG  1 
ATOM   11062 C CD  . PRO C 1 236 ? 130.681 182.135 92.697  1.00 58.85  ? 236 PRO C CD  1 
ATOM   11063 N N   . ALA C 1 237 ? 130.184 178.760 95.813  1.00 53.18  ? 237 ALA C N   1 
ATOM   11064 C CA  . ALA C 1 237 ? 130.337 178.517 97.238  1.00 52.62  ? 237 ALA C CA  1 
ATOM   11065 C C   . ALA C 1 237 ? 131.797 178.752 97.663  1.00 54.60  ? 237 ALA C C   1 
ATOM   11066 O O   . ALA C 1 237 ? 132.726 178.500 96.894  1.00 56.16  ? 237 ALA C O   1 
ATOM   11067 C CB  . ALA C 1 237 ? 129.908 177.087 97.558  1.00 51.41  ? 237 ALA C CB  1 
ATOM   11068 N N   . SER C 1 238 ? 132.013 179.193 98.899  1.00 44.30  ? 238 SER C N   1 
ATOM   11069 C CA  . SER C 1 238 ? 133.343 179.279 99.492  1.00 46.74  ? 238 SER C CA  1 
ATOM   11070 C C   . SER C 1 238 ? 133.507 178.198 100.555 1.00 46.04  ? 238 SER C C   1 
ATOM   11071 O O   . SER C 1 238 ? 132.643 177.998 101.405 1.00 49.21  ? 238 SER C O   1 
ATOM   11072 C CB  . SER C 1 238 ? 133.650 180.688 100.004 1.00 48.04  ? 238 SER C CB  1 
ATOM   11073 O OG  . SER C 1 238 ? 132.749 181.112 100.999 1.00 48.60  ? 238 SER C OG  1 
ATOM   11074 N N   . LEU C 1 239 ? 134.648 177.510 100.526 1.00 42.88  ? 239 LEU C N   1 
ATOM   11075 C CA  . LEU C 1 239 ? 135.023 176.526 101.546 1.00 42.11  ? 239 LEU C CA  1 
ATOM   11076 C C   . LEU C 1 239 ? 135.213 177.185 102.922 1.00 43.31  ? 239 LEU C C   1 
ATOM   11077 O O   . LEU C 1 239 ? 135.089 176.531 103.952 1.00 44.60  ? 239 LEU C O   1 
ATOM   11078 C CB  . LEU C 1 239 ? 136.303 175.811 101.081 1.00 38.98  ? 239 LEU C CB  1 
ATOM   11079 C CG  . LEU C 1 239 ? 136.074 174.936 99.839  1.00 42.76  ? 239 LEU C CG  1 
ATOM   11080 C CD1 . LEU C 1 239 ? 137.363 174.658 99.095  1.00 43.81  ? 239 LEU C CD1 1 
ATOM   11081 C CD2 . LEU C 1 239 ? 135.461 173.601 100.218 1.00 41.72  ? 239 LEU C CD2 1 
ATOM   11082 N N   . GLU C 1 240 ? 135.466 178.492 102.933 1.00 44.40  ? 240 GLU C N   1 
ATOM   11083 C CA  . GLU C 1 240 ? 135.594 179.338 104.116 1.00 42.92  ? 240 GLU C CA  1 
ATOM   11084 C C   . GLU C 1 240 ? 134.269 179.650 104.818 1.00 44.65  ? 240 GLU C C   1 
ATOM   11085 O O   . GLU C 1 240 ? 134.296 180.128 105.948 1.00 50.87  ? 240 GLU C O   1 
ATOM   11086 C CB  . GLU C 1 240 ? 136.193 180.690 103.711 1.00 45.86  ? 240 GLU C CB  1 
ATOM   11087 C CG  . GLU C 1 240 ? 137.528 180.621 102.975 1.00 46.07  ? 240 GLU C CG  1 
ATOM   11088 C CD  . GLU C 1 240 ? 138.044 182.041 102.716 1.00 52.24  ? 240 GLU C CD  1 
ATOM   11089 O OE1 . GLU C 1 240 ? 138.367 182.758 103.687 1.00 50.19  ? 240 GLU C OE1 1 
ATOM   11090 O OE2 . GLU C 1 240 ? 138.084 182.461 101.538 1.00 54.52  ? 240 GLU C OE2 1 
ATOM   11091 N N   . ALA C 1 241 ? 133.118 179.465 104.169 1.00 42.09  ? 241 ALA C N   1 
ATOM   11092 C CA  . ALA C 1 241 ? 131.829 179.876 104.722 1.00 39.61  ? 241 ALA C CA  1 
ATOM   11093 C C   . ALA C 1 241 ? 131.454 179.073 105.977 1.00 36.97  ? 241 ALA C C   1 
ATOM   11094 O O   . ALA C 1 241 ? 131.645 177.859 106.036 1.00 39.55  ? 241 ALA C O   1 
ATOM   11095 C CB  . ALA C 1 241 ? 130.753 179.768 103.643 1.00 41.33  ? 241 ALA C CB  1 
ATOM   11096 N N   . THR C 1 242 ? 130.887 179.750 106.974 1.00 37.09  ? 242 THR C N   1 
ATOM   11097 C CA  . THR C 1 242 ? 130.589 179.181 108.298 1.00 38.69  ? 242 THR C CA  1 
ATOM   11098 C C   . THR C 1 242 ? 129.113 179.259 108.676 1.00 36.50  ? 242 THR C C   1 
ATOM   11099 O O   . THR C 1 242 ? 128.385 180.166 108.266 1.00 41.05  ? 242 THR C O   1 
ATOM   11100 C CB  . THR C 1 242 ? 131.437 179.815 109.409 1.00 39.06  ? 242 THR C CB  1 
ATOM   11101 O OG1 . THR C 1 242 ? 131.254 181.207 109.452 1.00 44.88  ? 242 THR C OG1 1 
ATOM   11102 C CG2 . THR C 1 242 ? 132.924 179.534 109.257 1.00 34.83  ? 242 THR C CG2 1 
ATOM   11103 N N   . ASP C 1 243 ? 128.662 178.282 109.463 1.00 34.90  ? 243 ASP C N   1 
ATOM   11104 C CA  . ASP C 1 243 ? 127.263 178.297 109.979 1.00 31.94  ? 243 ASP C CA  1 
ATOM   11105 C C   . ASP C 1 243 ? 127.145 179.025 111.332 1.00 37.80  ? 243 ASP C C   1 
ATOM   11106 O O   . ASP C 1 243 ? 128.130 179.671 111.740 1.00 46.01  ? 243 ASP C O   1 
ATOM   11107 C CB  . ASP C 1 243 ? 126.712 176.874 110.102 1.00 33.87  ? 243 ASP C CB  1 
ATOM   11108 C CG  . ASP C 1 243 ? 127.365 176.068 111.212 1.00 38.18  ? 243 ASP C CG  1 
ATOM   11109 O OD1 . ASP C 1 243 ? 128.233 176.631 111.909 1.00 42.62  ? 243 ASP C OD1 1 
ATOM   11110 O OD2 . ASP C 1 243 ? 126.998 174.888 111.371 1.00 42.72  ? 243 ASP C OD2 1 
ATOM   11111 N N   . SER C 1 244 ? 125.990 178.917 111.994 1.00 40.28  ? 244 SER C N   1 
ATOM   11112 C CA  . SER C 1 244 ? 125.694 179.609 113.258 1.00 40.03  ? 244 SER C CA  1 
ATOM   11113 C C   . SER C 1 244 ? 126.546 179.176 114.463 1.00 42.75  ? 244 SER C C   1 
ATOM   11114 O O   . SER C 1 244 ? 126.542 179.871 115.475 1.00 47.88  ? 244 SER C O   1 
ATOM   11115 C CB  . SER C 1 244 ? 124.220 179.427 113.622 1.00 44.79  ? 244 SER C CB  1 
ATOM   11116 O OG  . SER C 1 244 ? 123.377 179.806 112.553 1.00 49.99  ? 244 SER C OG  1 
ATOM   11117 N N   . LEU C 1 245 ? 127.270 178.056 114.384 1.00 43.98  ? 245 LEU C N   1 
ATOM   11118 C CA  . LEU C 1 245 ? 128.282 177.614 115.358 1.00 35.77  ? 245 LEU C CA  1 
ATOM   11119 C C   . LEU C 1 245 ? 129.704 178.026 114.946 1.00 36.71  ? 245 LEU C C   1 
ATOM   11120 O O   . LEU C 1 245 ? 130.665 177.723 115.650 1.00 38.00  ? 245 LEU C O   1 
ATOM   11121 C CB  . LEU C 1 245 ? 128.221 176.086 115.527 1.00 37.06  ? 245 LEU C CB  1 
ATOM   11122 C CG  . LEU C 1 245 ? 126.912 175.525 116.094 1.00 39.58  ? 245 LEU C CG  1 
ATOM   11123 C CD1 . LEU C 1 245 ? 126.959 174.001 116.077 1.00 40.08  ? 245 LEU C CD1 1 
ATOM   11124 C CD2 . LEU C 1 245 ? 126.681 175.972 117.534 1.00 36.18  ? 245 LEU C CD2 1 
ATOM   11125 N N   . GLY C 1 246 ? 129.867 178.679 113.795 1.00 33.08  ? 246 GLY C N   1 
ATOM   11126 C CA  . GLY C 1 246 ? 131.152 178.981 113.181 1.00 25.62  ? 246 GLY C CA  1 
ATOM   11127 C C   . GLY C 1 246 ? 131.782 177.793 112.449 1.00 34.06  ? 246 GLY C C   1 
ATOM   11128 O O   . GLY C 1 246 ? 132.941 177.872 112.067 1.00 39.09  ? 246 GLY C O   1 
ATOM   11129 N N   . ASN C 1 247 ? 131.069 176.685 112.260 1.00 33.88  ? 247 ASN C N   1 
ATOM   11130 C CA  . ASN C 1 247 ? 131.595 175.503 111.589 1.00 25.19  ? 247 ASN C CA  1 
ATOM   11131 C C   . ASN C 1 247 ? 131.668 175.703 110.070 1.00 29.26  ? 247 ASN C C   1 
ATOM   11132 O O   . ASN C 1 247 ? 130.683 176.082 109.443 1.00 38.12  ? 247 ASN C O   1 
ATOM   11133 C CB  . ASN C 1 247 ? 130.735 174.285 111.967 1.00 24.05  ? 247 ASN C CB  1 
ATOM   11134 C CG  . ASN C 1 247 ? 130.951 173.801 113.383 1.00 26.15  ? 247 ASN C CG  1 
ATOM   11135 O OD1 . ASN C 1 247 ? 131.916 174.126 114.044 1.00 27.63  ? 247 ASN C OD1 1 
ATOM   11136 N ND2 . ASN C 1 247 ? 130.093 172.963 113.891 1.00 31.94  ? 247 ASN C ND2 1 
ATOM   11137 N N   . THR C 1 248 ? 132.824 175.417 109.475 1.00 30.79  ? 248 THR C N   1 
ATOM   11138 C CA  . THR C 1 248 ? 132.988 175.249 108.022 1.00 27.78  ? 248 THR C CA  1 
ATOM   11139 C C   . THR C 1 248 ? 132.468 173.883 107.567 1.00 20.28  ? 248 THR C C   1 
ATOM   11140 O O   . THR C 1 248 ? 132.094 173.042 108.380 1.00 33.21  ? 248 THR C O   1 
ATOM   11141 C CB  . THR C 1 248 ? 134.457 175.394 107.593 1.00 30.34  ? 248 THR C CB  1 
ATOM   11142 O OG1 . THR C 1 248 ? 135.234 174.314 108.066 1.00 34.73  ? 248 THR C OG1 1 
ATOM   11143 C CG2 . THR C 1 248 ? 135.107 176.699 108.031 1.00 27.88  ? 248 THR C CG2 1 
ATOM   11144 N N   . VAL C 1 249 ? 132.495 173.599 106.266 1.00 20.48  ? 249 VAL C N   1 
ATOM   11145 C CA  . VAL C 1 249 ? 132.201 172.252 105.752 1.00 24.97  ? 249 VAL C CA  1 
ATOM   11146 C C   . VAL C 1 249 ? 133.141 171.171 106.313 1.00 21.26  ? 249 VAL C C   1 
ATOM   11147 O O   . VAL C 1 249 ? 132.713 170.041 106.521 1.00 22.01  ? 249 VAL C O   1 
ATOM   11148 C CB  . VAL C 1 249 ? 132.172 172.268 104.214 1.00 25.94  ? 249 VAL C CB  1 
ATOM   11149 C CG1 . VAL C 1 249 ? 133.499 172.685 103.579 1.00 21.65  ? 249 VAL C CG1 1 
ATOM   11150 C CG2 . VAL C 1 249 ? 131.760 170.911 103.655 1.00 24.17  ? 249 VAL C CG2 1 
ATOM   11151 N N   . LEU C 1 250 ? 134.396 171.493 106.645 1.00 29.96  ? 250 LEU C N   1 
ATOM   11152 C CA  . LEU C 1 250 ? 135.329 170.537 107.252 1.00 23.13  ? 250 LEU C CA  1 
ATOM   11153 C C   . LEU C 1 250 ? 134.994 170.246 108.716 1.00 24.29  ? 250 LEU C C   1 
ATOM   11154 O O   . LEU C 1 250 ? 135.097 169.103 109.152 1.00 27.98  ? 250 LEU C O   1 
ATOM   11155 C CB  . LEU C 1 250 ? 136.773 171.041 107.122 1.00 21.02  ? 250 LEU C CB  1 
ATOM   11156 C CG  . LEU C 1 250 ? 137.297 171.194 105.688 1.00 25.33  ? 250 LEU C CG  1 
ATOM   11157 C CD1 . LEU C 1 250 ? 138.755 171.643 105.749 1.00 30.18  ? 250 LEU C CD1 1 
ATOM   11158 C CD2 . LEU C 1 250 ? 137.238 169.903 104.876 1.00 20.23  ? 250 LEU C CD2 1 
ATOM   11159 N N   . HIS C 1 251 ? 134.524 171.239 109.469 1.00 27.71  ? 251 HIS C N   1 
ATOM   11160 C CA  . HIS C 1 251 ? 133.954 171.021 110.799 1.00 15.90  ? 251 HIS C CA  1 
ATOM   11161 C C   . HIS C 1 251 ? 132.661 170.208 110.739 1.00 23.68  ? 251 HIS C C   1 
ATOM   11162 O O   . HIS C 1 251 ? 132.512 169.293 111.572 1.00 31.90  ? 251 HIS C O   1 
ATOM   11163 C CB  . HIS C 1 251 ? 133.684 172.367 111.488 1.00 19.81  ? 251 HIS C CB  1 
ATOM   11164 C CG  . HIS C 1 251 ? 134.907 173.168 111.789 1.00 18.53  ? 251 HIS C CG  1 
ATOM   11165 N ND1 . HIS C 1 251 ? 135.368 174.156 110.940 1.00 20.49  ? 251 HIS C ND1 1 
ATOM   11166 C CD2 . HIS C 1 251 ? 135.754 173.143 112.841 1.00 23.02  ? 251 HIS C CD2 1 
ATOM   11167 C CE1 . HIS C 1 251 ? 136.452 174.701 111.454 1.00 27.82  ? 251 HIS C CE1 1 
ATOM   11168 N NE2 . HIS C 1 251 ? 136.708 174.097 112.621 1.00 34.92  ? 251 HIS C NE2 1 
ATOM   11169 N N   . ALA C 1 252 ? 131.768 170.511 109.796 1.00 28.18  ? 252 ALA C N   1 
ATOM   11170 C CA  . ALA C 1 252 ? 130.539 169.762 109.578 1.00 11.95  ? 252 ALA C CA  1 
ATOM   11171 C C   . ALA C 1 252 ? 130.805 168.286 109.242 1.00 15.52  ? 252 ALA C C   1 
ATOM   11172 O O   . ALA C 1 252 ? 130.134 167.417 109.781 1.00 26.86  ? 252 ALA C O   1 
ATOM   11173 C CB  . ALA C 1 252 ? 129.727 170.456 108.488 1.00 18.76  ? 252 ALA C CB  1 
ATOM   11174 N N   . LEU C 1 253 ? 131.813 167.968 108.439 1.00 23.12  ? 253 LEU C N   1 
ATOM   11175 C CA  . LEU C 1 253 ? 132.207 166.585 108.173 1.00 20.48  ? 253 LEU C CA  1 
ATOM   11176 C C   . LEU C 1 253 ? 132.678 165.840 109.425 1.00 25.50  ? 253 LEU C C   1 
ATOM   11177 O O   . LEU C 1 253 ? 132.292 164.699 109.643 1.00 35.87  ? 253 LEU C O   1 
ATOM   11178 C CB  . LEU C 1 253 ? 133.289 166.589 107.089 1.00 22.31  ? 253 LEU C CB  1 
ATOM   11179 C CG  . LEU C 1 253 ? 132.684 166.669 105.685 1.00 27.24  ? 253 LEU C CG  1 
ATOM   11180 C CD1 . LEU C 1 253 ? 133.744 167.103 104.696 1.00 29.89  ? 253 LEU C CD1 1 
ATOM   11181 C CD2 . LEU C 1 253 ? 132.178 165.303 105.239 1.00 28.53  ? 253 LEU C CD2 1 
ATOM   11182 N N   . VAL C 1 254 ? 133.454 166.489 110.291 1.00 23.38  ? 254 VAL C N   1 
ATOM   11183 C CA  . VAL C 1 254 ? 133.803 165.946 111.609 1.00 19.83  ? 254 VAL C CA  1 
ATOM   11184 C C   . VAL C 1 254 ? 132.553 165.733 112.475 1.00 26.60  ? 254 VAL C C   1 
ATOM   11185 O O   . VAL C 1 254 ? 132.429 164.711 113.147 1.00 33.89  ? 254 VAL C O   1 
ATOM   11186 C CB  . VAL C 1 254 ? 134.848 166.854 112.283 1.00 23.87  ? 254 VAL C CB  1 
ATOM   11187 C CG1 . VAL C 1 254 ? 135.081 166.497 113.744 1.00 21.26  ? 254 VAL C CG1 1 
ATOM   11188 C CG2 . VAL C 1 254 ? 136.192 166.746 111.557 1.00 16.74  ? 254 VAL C CG2 1 
ATOM   11189 N N   . MET C 1 255 ? 131.578 166.638 112.433 1.00 22.15  ? 255 MET C N   1 
ATOM   11190 C CA  . MET C 1 255 ? 130.307 166.490 113.139 1.00 14.53  ? 255 MET C CA  1 
ATOM   11191 C C   . MET C 1 255 ? 129.423 165.345 112.619 1.00 23.85  ? 255 MET C C   1 
ATOM   11192 O O   . MET C 1 255 ? 128.788 164.703 113.447 1.00 31.57  ? 255 MET C O   1 
ATOM   11193 C CB  . MET C 1 255 ? 129.533 167.808 113.131 1.00 24.33  ? 255 MET C CB  1 
ATOM   11194 C CG  . MET C 1 255 ? 130.180 168.896 113.986 1.00 22.89  ? 255 MET C CG  1 
ATOM   11195 S SD  . MET C 1 255 ? 130.252 168.514 115.755 1.00 45.65  ? 255 MET C SD  1 
ATOM   11196 C CE  . MET C 1 255 ? 130.144 170.188 116.437 1.00 29.01  ? 255 MET C CE  1 
ATOM   11197 N N   . ILE C 1 256 ? 129.416 165.009 111.321 1.00 27.68  ? 256 ILE C N   1 
ATOM   11198 C CA  . ILE C 1 256 ? 128.642 163.827 110.820 1.00 25.01  ? 256 ILE C CA  1 
ATOM   11199 C C   . ILE C 1 256 ? 129.376 162.486 111.044 1.00 30.62  ? 256 ILE C C   1 
ATOM   11200 O O   . ILE C 1 256 ? 128.754 161.452 110.734 1.00 41.06  ? 256 ILE C O   1 
ATOM   11201 C CB  . ILE C 1 256 ? 128.288 164.017 109.330 1.00 27.54  ? 256 ILE C CB  1 
ATOM   11202 C CG1 . ILE C 1 256 ? 129.534 163.977 108.443 1.00 27.38  ? 256 ILE C CG1 1 
ATOM   11203 C CG2 . ILE C 1 256 ? 127.486 165.294 109.125 1.00 27.03  ? 256 ILE C CG2 1 
ATOM   11204 C CD1 . ILE C 1 256 ? 129.237 164.063 106.965 1.00 27.01  ? 256 ILE C CD1 1 
ATOM   11205 N N   . ALA C 1 257 ? 130.621 162.465 111.545 1.00 28.72  ? 257 ALA C N   1 
ATOM   11206 C CA  . ALA C 1 257 ? 131.343 161.217 111.695 1.00 25.99  ? 257 ALA C CA  1 
ATOM   11207 C C   . ALA C 1 257 ? 130.845 160.363 112.869 1.00 34.53  ? 257 ALA C C   1 
ATOM   11208 O O   . ALA C 1 257 ? 130.784 160.824 114.009 1.00 37.47  ? 257 ALA C O   1 
ATOM   11209 C CB  . ALA C 1 257 ? 132.835 161.541 111.812 1.00 24.71  ? 257 ALA C CB  1 
ATOM   11210 N N   . ASP C 1 258 ? 130.511 159.110 112.603 1.00 43.05  ? 258 ASP C N   1 
ATOM   11211 C CA  . ASP C 1 258 ? 130.481 157.997 113.575 1.00 43.07  ? 258 ASP C CA  1 
ATOM   11212 C C   . ASP C 1 258 ? 131.792 157.180 113.290 1.00 48.74  ? 258 ASP C C   1 
ATOM   11213 O O   . ASP C 1 258 ? 132.459 157.466 112.276 1.00 49.14  ? 258 ASP C O   1 
ATOM   11214 C CB  . ASP C 1 258 ? 129.208 157.159 113.450 1.00 47.09  ? 258 ASP C CB  1 
ATOM   11215 C CG  . ASP C 1 258 ? 129.230 156.205 112.268 1.00 51.53  ? 258 ASP C CG  1 
ATOM   11216 O OD1 . ASP C 1 258 ? 130.337 155.885 111.796 1.00 53.99  ? 258 ASP C OD1 1 
ATOM   11217 O OD2 . ASP C 1 258 ? 128.138 155.790 111.831 1.00 47.82  ? 258 ASP C OD2 1 
ATOM   11218 N N   . ASN C 1 259 ? 132.118 156.237 114.166 1.00 44.34  ? 259 ASN C N   1 
ATOM   11219 C CA  . ASN C 1 259 ? 133.378 155.500 114.064 1.00 45.47  ? 259 ASN C CA  1 
ATOM   11220 C C   . ASN C 1 259 ? 133.237 154.151 113.334 1.00 51.16  ? 259 ASN C C   1 
ATOM   11221 O O   . ASN C 1 259 ? 134.139 153.318 113.395 1.00 53.07  ? 259 ASN C O   1 
ATOM   11222 C CB  . ASN C 1 259 ? 134.030 155.466 115.454 1.00 47.98  ? 259 ASN C CB  1 
ATOM   11223 C CG  . ASN C 1 259 ? 134.269 156.873 115.976 1.00 42.84  ? 259 ASN C CG  1 
ATOM   11224 O OD1 . ASN C 1 259 ? 135.039 157.642 115.430 1.00 42.71  ? 259 ASN C OD1 1 
ATOM   11225 N ND2 . ASN C 1 259 ? 133.599 157.274 117.029 1.00 43.99  ? 259 ASN C ND2 1 
ATOM   11226 N N   . SER C 1 260 ? 132.123 153.919 112.628 1.00 53.19  ? 260 SER C N   1 
ATOM   11227 C CA  . SER C 1 260 ? 131.953 152.767 111.732 1.00 52.24  ? 260 SER C CA  1 
ATOM   11228 C C   . SER C 1 260 ? 132.820 152.919 110.469 1.00 52.92  ? 260 SER C C   1 
ATOM   11229 O O   . SER C 1 260 ? 133.100 154.047 110.047 1.00 51.49  ? 260 SER C O   1 
ATOM   11230 C CB  . SER C 1 260 ? 130.480 152.579 111.364 1.00 55.32  ? 260 SER C CB  1 
ATOM   11231 O OG  . SER C 1 260 ? 130.040 153.594 110.496 1.00 54.95  ? 260 SER C OG  1 
ATOM   11232 N N   . PRO C 1 261 ? 133.281 151.820 109.846 1.00 58.49  ? 261 PRO C N   1 
ATOM   11233 C CA  . PRO C 1 261 ? 134.287 151.894 108.786 1.00 56.57  ? 261 PRO C CA  1 
ATOM   11234 C C   . PRO C 1 261 ? 133.764 152.516 107.488 1.00 54.33  ? 261 PRO C C   1 
ATOM   11235 O O   . PRO C 1 261 ? 134.494 153.258 106.834 1.00 54.56  ? 261 PRO C O   1 
ATOM   11236 C CB  . PRO C 1 261 ? 134.776 150.457 108.589 1.00 54.71  ? 261 PRO C CB  1 
ATOM   11237 C CG  . PRO C 1 261 ? 133.628 149.599 109.108 1.00 54.24  ? 261 PRO C CG  1 
ATOM   11238 C CD  . PRO C 1 261 ? 133.051 150.440 110.237 1.00 52.77  ? 261 PRO C CD  1 
ATOM   11239 N N   . GLU C 1 262 ? 132.500 152.283 107.129 1.00 55.90  ? 262 GLU C N   1 
ATOM   11240 C CA  . GLU C 1 262 ? 131.884 152.880 105.940 1.00 57.87  ? 262 GLU C CA  1 
ATOM   11241 C C   . GLU C 1 262 ? 131.673 154.388 106.113 1.00 58.14  ? 262 GLU C C   1 
ATOM   11242 O O   . GLU C 1 262 ? 132.131 155.169 105.286 1.00 61.30  ? 262 GLU C O   1 
ATOM   11243 C CB  . GLU C 1 262 ? 130.586 152.144 105.573 1.00 58.17  ? 262 GLU C CB  1 
ATOM   11244 C CG  . GLU C 1 262 ? 129.932 152.730 104.311 1.00 61.81  ? 262 GLU C CG  1 
ATOM   11245 C CD  . GLU C 1 262 ? 128.883 151.815 103.664 1.00 64.93  ? 262 GLU C CD  1 
ATOM   11246 O OE1 . GLU C 1 262 ? 128.317 150.934 104.347 1.00 61.46  ? 262 GLU C OE1 1 
ATOM   11247 O OE2 . GLU C 1 262 ? 128.611 151.984 102.452 1.00 63.73  ? 262 GLU C OE2 1 
ATOM   11248 N N   . ASN C 1 263 ? 131.066 154.828 107.215 1.00 49.25  ? 263 ASN C N   1 
ATOM   11249 C CA  . ASN C 1 263 ? 130.915 156.258 107.483 1.00 46.54  ? 263 ASN C CA  1 
ATOM   11250 C C   . ASN C 1 263 ? 132.273 156.975 107.548 1.00 47.73  ? 263 ASN C C   1 
ATOM   11251 O O   . ASN C 1 263 ? 132.420 158.066 107.002 1.00 47.51  ? 263 ASN C O   1 
ATOM   11252 C CB  . ASN C 1 263 ? 130.141 156.447 108.787 1.00 45.76  ? 263 ASN C CB  1 
ATOM   11253 C CG  . ASN C 1 263 ? 129.989 157.914 109.111 1.00 46.36  ? 263 ASN C CG  1 
ATOM   11254 O OD1 . ASN C 1 263 ? 130.778 158.498 109.829 1.00 48.67  ? 263 ASN C OD1 1 
ATOM   11255 N ND2 . ASN C 1 263 ? 129.008 158.580 108.571 1.00 47.46  ? 263 ASN C ND2 1 
ATOM   11256 N N   . SER C 1 264 ? 133.284 156.341 108.142 1.00 47.72  ? 264 SER C N   1 
ATOM   11257 C CA  . SER C 1 264 ? 134.634 156.892 108.199 1.00 42.28  ? 264 SER C CA  1 
ATOM   11258 C C   . SER C 1 264 ? 135.233 157.050 106.807 1.00 41.62  ? 264 SER C C   1 
ATOM   11259 O O   . SER C 1 264 ? 135.688 158.138 106.475 1.00 42.97  ? 264 SER C O   1 
ATOM   11260 C CB  . SER C 1 264 ? 135.545 156.028 109.064 1.00 46.36  ? 264 SER C CB  1 
ATOM   11261 O OG  . SER C 1 264 ? 135.019 155.929 110.364 1.00 46.80  ? 264 SER C OG  1 
ATOM   11262 N N   . ALA C 1 265 ? 135.192 156.021 105.958 1.00 49.65  ? 265 ALA C N   1 
ATOM   11263 C CA  . ALA C 1 265 ? 135.710 156.099 104.593 1.00 49.28  ? 265 ALA C CA  1 
ATOM   11264 C C   . ALA C 1 265 ? 135.051 157.222 103.780 1.00 45.20  ? 265 ALA C C   1 
ATOM   11265 O O   . ALA C 1 265 ? 135.730 157.944 103.056 1.00 49.34  ? 265 ALA C O   1 
ATOM   11266 C CB  . ALA C 1 265 ? 135.507 154.740 103.920 1.00 46.66  ? 265 ALA C CB  1 
ATOM   11267 N N   . LEU C 1 266 ? 133.741 157.416 103.940 1.00 39.15  ? 266 LEU C N   1 
ATOM   11268 C CA  . LEU C 1 266 ? 132.987 158.458 103.249 1.00 43.73  ? 266 LEU C CA  1 
ATOM   11269 C C   . LEU C 1 266 ? 133.282 159.869 103.771 1.00 42.38  ? 266 LEU C C   1 
ATOM   11270 O O   . LEU C 1 266 ? 133.505 160.773 102.967 1.00 44.06  ? 266 LEU C O   1 
ATOM   11271 C CB  . LEU C 1 266 ? 131.492 158.104 103.304 1.00 48.84  ? 266 LEU C CB  1 
ATOM   11272 C CG  . LEU C 1 266 ? 131.159 156.778 102.591 1.00 49.43  ? 266 LEU C CG  1 
ATOM   11273 C CD1 . LEU C 1 266 ? 129.688 156.440 102.796 1.00 48.26  ? 266 LEU C CD1 1 
ATOM   11274 C CD2 . LEU C 1 266 ? 131.494 156.820 101.104 1.00 44.61  ? 266 LEU C CD2 1 
ATOM   11275 N N   . VAL C 1 267 ? 133.369 160.072 105.086 1.00 42.74  ? 267 VAL C N   1 
ATOM   11276 C CA  . VAL C 1 267 ? 133.811 161.354 105.664 1.00 38.93  ? 267 VAL C CA  1 
ATOM   11277 C C   . VAL C 1 267 ? 135.249 161.686 105.254 1.00 38.13  ? 267 VAL C C   1 
ATOM   11278 O O   . VAL C 1 267 ? 135.519 162.803 104.834 1.00 41.74  ? 267 VAL C O   1 
ATOM   11279 C CB  . VAL C 1 267 ? 133.642 161.363 107.195 1.00 38.99  ? 267 VAL C CB  1 
ATOM   11280 C CG1 . VAL C 1 267 ? 134.341 162.545 107.863 1.00 41.37  ? 267 VAL C CG1 1 
ATOM   11281 C CG2 . VAL C 1 267 ? 132.163 161.454 107.554 1.00 32.21  ? 267 VAL C CG2 1 
ATOM   11282 N N   . ILE C 1 268 ? 136.162 160.718 105.312 1.00 30.75  ? 268 ILE C N   1 
ATOM   11283 C CA  . ILE C 1 268 ? 137.569 160.873 104.935 1.00 35.51  ? 268 ILE C CA  1 
ATOM   11284 C C   . ILE C 1 268 ? 137.731 161.236 103.449 1.00 39.25  ? 268 ILE C C   1 
ATOM   11285 O O   . ILE C 1 268 ? 138.444 162.185 103.132 1.00 41.13  ? 268 ILE C O   1 
ATOM   11286 C CB  . ILE C 1 268 ? 138.347 159.602 105.345 1.00 35.82  ? 268 ILE C CB  1 
ATOM   11287 C CG1 . ILE C 1 268 ? 138.518 159.592 106.882 1.00 27.95  ? 268 ILE C CG1 1 
ATOM   11288 C CG2 . ILE C 1 268 ? 139.699 159.489 104.634 1.00 30.70  ? 268 ILE C CG2 1 
ATOM   11289 C CD1 . ILE C 1 268 ? 138.958 158.251 107.464 1.00 31.66  ? 268 ILE C CD1 1 
ATOM   11290 N N   . HIS C 1 269 ? 137.044 160.552 102.526 1.00 39.45  ? 269 HIS C N   1 
ATOM   11291 C CA  . HIS C 1 269 ? 137.110 160.893 101.100 1.00 41.19  ? 269 HIS C CA  1 
ATOM   11292 C C   . HIS C 1 269 ? 136.600 162.303 100.815 1.00 40.24  ? 269 HIS C C   1 
ATOM   11293 O O   . HIS C 1 269 ? 137.209 163.045 100.050 1.00 42.38  ? 269 HIS C O   1 
ATOM   11294 C CB  . HIS C 1 269 ? 136.330 159.878 100.248 1.00 45.24  ? 269 HIS C CB  1 
ATOM   11295 C CG  . HIS C 1 269 ? 137.060 158.582 100.007 1.00 49.32  ? 269 HIS C CG  1 
ATOM   11296 N ND1 . HIS C 1 269 ? 138.337 158.471 99.457  1.00 50.39  ? 269 HIS C ND1 1 
ATOM   11297 C CD2 . HIS C 1 269 ? 136.546 157.326 100.163 1.00 49.68  ? 269 HIS C CD2 1 
ATOM   11298 C CE1 . HIS C 1 269 ? 138.579 157.156 99.335  1.00 48.70  ? 269 HIS C CE1 1 
ATOM   11299 N NE2 . HIS C 1 269 ? 137.521 156.446 99.752  1.00 51.32  ? 269 HIS C NE2 1 
ATOM   11300 N N   . MET C 1 270 ? 135.495 162.697 101.442 1.00 37.54  ? 270 MET C N   1 
ATOM   11301 C CA  . MET C 1 270 ? 134.918 164.024 101.269 1.00 35.45  ? 270 MET C CA  1 
ATOM   11302 C C   . MET C 1 270 ? 135.813 165.120 101.857 1.00 34.54  ? 270 MET C C   1 
ATOM   11303 O O   . MET C 1 270 ? 136.050 166.138 101.211 1.00 35.64  ? 270 MET C O   1 
ATOM   11304 C CB  . MET C 1 270 ? 133.528 164.018 101.904 1.00 30.50  ? 270 MET C CB  1 
ATOM   11305 C CG  . MET C 1 270 ? 132.636 165.166 101.428 1.00 33.33  ? 270 MET C CG  1 
ATOM   11306 S SD  . MET C 1 270 ? 132.141 165.184 99.678  1.00 50.01  ? 270 MET C SD  1 
ATOM   11307 C CE  . MET C 1 270 ? 131.808 163.438 99.352  1.00 33.81  ? 270 MET C CE  1 
ATOM   11308 N N   . TYR C 1 271 ? 136.377 164.888 103.043 1.00 32.75  ? 271 TYR C N   1 
ATOM   11309 C CA  . TYR C 1 271 ? 137.302 165.793 103.719 1.00 24.68  ? 271 TYR C CA  1 
ATOM   11310 C C   . TYR C 1 271 ? 138.584 166.031 102.900 1.00 33.32  ? 271 TYR C C   1 
ATOM   11311 O O   . TYR C 1 271 ? 138.963 167.177 102.677 1.00 32.03  ? 271 TYR C O   1 
ATOM   11312 C CB  . TYR C 1 271 ? 137.589 165.215 105.115 1.00 29.68  ? 271 TYR C CB  1 
ATOM   11313 C CG  . TYR C 1 271 ? 138.307 166.154 106.057 1.00 28.78  ? 271 TYR C CG  1 
ATOM   11314 C CD1 . TYR C 1 271 ? 139.677 166.411 105.882 1.00 29.57  ? 271 TYR C CD1 1 
ATOM   11315 C CD2 . TYR C 1 271 ? 137.603 166.778 107.105 1.00 27.27  ? 271 TYR C CD2 1 
ATOM   11316 C CE1 . TYR C 1 271 ? 140.332 167.325 106.717 1.00 27.51  ? 271 TYR C CE1 1 
ATOM   11317 C CE2 . TYR C 1 271 ? 138.265 167.682 107.953 1.00 34.58  ? 271 TYR C CE2 1 
ATOM   11318 C CZ  . TYR C 1 271 ? 139.626 167.971 107.747 1.00 30.57  ? 271 TYR C CZ  1 
ATOM   11319 O OH  . TYR C 1 271 ? 140.273 168.848 108.544 1.00 31.93  ? 271 TYR C OH  1 
ATOM   11320 N N   . ASP C 1 272 ? 139.221 164.972 102.399 1.00 34.76  ? 272 ASP C N   1 
ATOM   11321 C CA  . ASP C 1 272 ? 140.399 165.087 101.536 1.00 31.24  ? 272 ASP C CA  1 
ATOM   11322 C C   . ASP C 1 272 ? 140.088 165.768 100.205 1.00 37.95  ? 272 ASP C C   1 
ATOM   11323 O O   . ASP C 1 272 ? 140.856 166.617 99.758  1.00 41.13  ? 272 ASP C O   1 
ATOM   11324 C CB  . ASP C 1 272 ? 140.994 163.704 101.255 1.00 39.06  ? 272 ASP C CB  1 
ATOM   11325 C CG  . ASP C 1 272 ? 141.747 163.079 102.430 1.00 44.94  ? 272 ASP C CG  1 
ATOM   11326 O OD1 . ASP C 1 272 ? 141.976 163.750 103.459 1.00 38.57  ? 272 ASP C OD1 1 
ATOM   11327 O OD2 . ASP C 1 272 ? 142.180 161.915 102.276 1.00 48.63  ? 272 ASP C OD2 1 
ATOM   11328 N N   . GLY C 1 273 ? 138.950 165.446 99.584  1.00 42.45  ? 273 GLY C N   1 
ATOM   11329 C CA  . GLY C 1 273 ? 138.488 166.092 98.367  1.00 31.66  ? 273 GLY C CA  1 
ATOM   11330 C C   . GLY C 1 273 ? 138.326 167.595 98.547  1.00 34.31  ? 273 GLY C C   1 
ATOM   11331 O O   . GLY C 1 273 ? 138.786 168.367 97.711  1.00 40.70  ? 273 GLY C O   1 
ATOM   11332 N N   . LEU C 1 274 ? 137.719 168.048 99.642  1.00 34.18  ? 274 LEU C N   1 
ATOM   11333 C CA  . LEU C 1 274 ? 137.531 169.473 99.901  1.00 35.65  ? 274 LEU C CA  1 
ATOM   11334 C C   . LEU C 1 274 ? 138.842 170.208 100.206 1.00 39.69  ? 274 LEU C C   1 
ATOM   11335 O O   . LEU C 1 274 ? 138.997 171.347 99.778  1.00 40.38  ? 274 LEU C O   1 
ATOM   11336 C CB  . LEU C 1 274 ? 136.525 169.649 101.036 1.00 33.09  ? 274 LEU C CB  1 
ATOM   11337 C CG  . LEU C 1 274 ? 135.098 169.233 100.660 1.00 34.17  ? 274 LEU C CG  1 
ATOM   11338 C CD1 . LEU C 1 274 ? 134.316 169.081 101.944 1.00 36.90  ? 274 LEU C CD1 1 
ATOM   11339 C CD2 . LEU C 1 274 ? 134.365 170.257 99.804  1.00 30.35  ? 274 LEU C CD2 1 
ATOM   11340 N N   . LEU C 1 275 ? 139.819 169.584 100.869 1.00 40.52  ? 275 LEU C N   1 
ATOM   11341 C CA  . LEU C 1 275 ? 141.159 170.167 100.985 1.00 37.48  ? 275 LEU C CA  1 
ATOM   11342 C C   . LEU C 1 275 ? 141.857 170.307 99.633  1.00 37.73  ? 275 LEU C C   1 
ATOM   11343 O O   . LEU C 1 275 ? 142.428 171.355 99.348  1.00 40.51  ? 275 LEU C O   1 
ATOM   11344 C CB  . LEU C 1 275 ? 142.047 169.319 101.898 1.00 39.89  ? 275 LEU C CB  1 
ATOM   11345 C CG  . LEU C 1 275 ? 141.740 169.414 103.390 1.00 36.61  ? 275 LEU C CG  1 
ATOM   11346 C CD1 . LEU C 1 275 ? 142.761 168.547 104.112 1.00 33.31  ? 275 LEU C CD1 1 
ATOM   11347 C CD2 . LEU C 1 275 ? 141.879 170.835 103.923 1.00 33.25  ? 275 LEU C CD2 1 
ATOM   11348 N N   . GLN C 1 276 ? 141.746 169.272 98.799  1.00 41.74  ? 276 GLN C N   1 
ATOM   11349 C CA  . GLN C 1 276 ? 142.334 169.328 97.431  1.00 38.63  ? 276 GLN C CA  1 
ATOM   11350 C C   . GLN C 1 276 ? 141.648 170.455 96.656  1.00 47.72  ? 276 GLN C C   1 
ATOM   11351 O O   . GLN C 1 276 ? 142.375 171.243 96.019  1.00 51.34  ? 276 GLN C O   1 
ATOM   11352 C CB  . GLN C 1 276 ? 142.199 167.971 96.740  1.00 41.81  ? 276 GLN C CB  1 
ATOM   11353 C CG  . GLN C 1 276 ? 143.007 166.877 97.422  1.00 42.18  ? 276 GLN C CG  1 
ATOM   11354 C CD  . GLN C 1 276 ? 143.257 165.693 96.522  1.00 49.93  ? 276 GLN C CD  1 
ATOM   11355 O OE1 . GLN C 1 276 ? 142.699 165.587 95.433  1.00 52.54  ? 276 GLN C OE1 1 
ATOM   11356 N NE2 . GLN C 1 276 ? 144.111 164.789 96.974  1.00 48.66  ? 276 GLN C NE2 1 
ATOM   11357 N N   . MET C 1 277 ? 140.313 170.548 96.704  1.00 49.97  ? 277 MET C N   1 
ATOM   11358 C CA  . MET C 1 277 ? 139.580 171.662 96.099  1.00 48.63  ? 277 MET C CA  1 
ATOM   11359 C C   . MET C 1 277 ? 140.045 173.018 96.631  1.00 46.20  ? 277 MET C C   1 
ATOM   11360 O O   . MET C 1 277 ? 140.294 173.923 95.841  1.00 51.66  ? 277 MET C O   1 
ATOM   11361 C CB  . MET C 1 277 ? 138.069 171.502 96.327  1.00 50.79  ? 277 MET C CB  1 
ATOM   11362 C CG  . MET C 1 277 ? 137.460 170.399 95.469  1.00 48.27  ? 277 MET C CG  1 
ATOM   11363 S SD  . MET C 1 277 ? 137.261 170.854 93.734  1.00 69.24  ? 277 MET C SD  1 
ATOM   11364 C CE  . MET C 1 277 ? 137.364 169.214 92.990  1.00 58.70  ? 277 MET C CE  1 
ATOM   11365 N N   . GLY C 1 278 ? 140.228 173.185 97.940  1.00 46.73  ? 278 GLY C N   1 
ATOM   11366 C CA  . GLY C 1 278 ? 140.737 174.423 98.527  1.00 47.91  ? 278 GLY C CA  1 
ATOM   11367 C C   . GLY C 1 278 ? 142.133 174.794 98.032  1.00 48.92  ? 278 GLY C C   1 
ATOM   11368 O O   . GLY C 1 278 ? 142.396 175.956 97.733  1.00 49.41  ? 278 GLY C O   1 
ATOM   11369 N N   . ALA C 1 279 ? 143.003 173.806 97.826  1.00 49.60  ? 279 ALA C N   1 
ATOM   11370 C CA  . ALA C 1 279 ? 144.319 173.985 97.227  1.00 48.29  ? 279 ALA C CA  1 
ATOM   11371 C C   . ALA C 1 279 ? 144.288 174.500 95.770  1.00 54.46  ? 279 ALA C C   1 
ATOM   11372 O O   . ALA C 1 279 ? 145.294 175.018 95.290  1.00 56.63  ? 279 ALA C O   1 
ATOM   11373 C CB  . ALA C 1 279 ? 145.063 172.654 97.344  1.00 46.44  ? 279 ALA C CB  1 
ATOM   11374 N N   . ARG C 1 280 ? 143.092 174.482 95.143  1.00 57.81  ? 280 ARG C N   1 
ATOM   11375 C CA  . ARG C 1 280 ? 142.905 174.969 93.739  1.00 52.49  ? 280 ARG C CA  1 
ATOM   11376 C C   . ARG C 1 280 ? 142.028 176.218 93.673  1.00 55.16  ? 280 ARG C C   1 
ATOM   11377 O O   . ARG C 1 280 ? 142.225 177.017 92.739  1.00 59.55  ? 280 ARG C O   1 
ATOM   11378 C CB  . ARG C 1 280 ? 142.122 173.963 92.884  1.00 54.75  ? 280 ARG C CB  1 
ATOM   11379 C CG  . ARG C 1 280 ? 142.891 172.661 92.610  1.00 56.41  ? 280 ARG C CG  1 
ATOM   11380 C CD  . ARG C 1 280 ? 141.995 171.587 91.987  1.00 58.94  ? 280 ARG C CD  1 
ATOM   11381 N NE  . ARG C 1 280 ? 141.321 172.081 90.795  1.00 61.25  ? 280 ARG C NE  1 
ATOM   11382 C CZ  . ARG C 1 280 ? 140.152 172.710 90.799  1.00 60.77  ? 280 ARG C CZ  1 
ATOM   11383 N NH1 . ARG C 1 280 ? 139.620 173.123 89.661  1.00 57.67  ? 280 ARG C NH1 1 
ATOM   11384 N NH2 . ARG C 1 280 ? 139.518 172.925 91.938  1.00 57.95  ? 280 ARG C NH2 1 
ATOM   11385 N N   . LEU C 1 281 ? 141.098 176.383 94.611  1.00 54.01  ? 281 LEU C N   1 
ATOM   11386 C CA  . LEU C 1 281 ? 140.093 177.454 94.580  1.00 52.67  ? 281 LEU C CA  1 
ATOM   11387 C C   . LEU C 1 281 ? 140.353 178.606 95.555  1.00 52.16  ? 281 LEU C C   1 
ATOM   11388 O O   . LEU C 1 281 ? 139.904 179.725 95.313  1.00 55.13  ? 281 LEU C O   1 
ATOM   11389 C CB  . LEU C 1 281 ? 138.717 176.842 94.868  1.00 51.21  ? 281 LEU C CB  1 
ATOM   11390 C CG  . LEU C 1 281 ? 138.263 175.783 93.852  1.00 54.03  ? 281 LEU C CG  1 
ATOM   11391 C CD1 . LEU C 1 281 ? 136.980 175.152 94.360  1.00 55.20  ? 281 LEU C CD1 1 
ATOM   11392 C CD2 . LEU C 1 281 ? 138.001 176.382 92.475  1.00 52.03  ? 281 LEU C CD2 1 
ATOM   11393 N N   . CYS C 1 282 ? 141.077 178.359 96.642  1.00 53.10  ? 282 CYS C N   1 
ATOM   11394 C CA  . CYS C 1 282 ? 141.491 179.370 97.613  1.00 51.35  ? 282 CYS C CA  1 
ATOM   11395 C C   . CYS C 1 282 ? 142.889 179.036 98.172  1.00 54.30  ? 282 CYS C C   1 
ATOM   11396 O O   . CYS C 1 282 ? 143.053 178.869 99.381  1.00 57.03  ? 282 CYS C O   1 
ATOM   11397 C CB  . CYS C 1 282 ? 140.385 179.551 98.673  1.00 53.08  ? 282 CYS C CB  1 
ATOM   11398 S SG  . CYS C 1 282 ? 139.906 178.001 99.491  1.00 55.21  ? 282 CYS C SG  1 
ATOM   11399 N N   . PRO C 1 283 ? 143.936 178.951 97.326  1.00 58.04  ? 283 PRO C N   1 
ATOM   11400 C CA  . PRO C 1 283 ? 145.244 178.406 97.704  1.00 57.18  ? 283 PRO C CA  1 
ATOM   11401 C C   . PRO C 1 283 ? 145.979 179.218 98.783  1.00 57.37  ? 283 PRO C C   1 
ATOM   11402 O O   . PRO C 1 283 ? 146.827 178.683 99.493  1.00 57.58  ? 283 PRO C O   1 
ATOM   11403 C CB  . PRO C 1 283 ? 146.046 178.353 96.402  1.00 54.58  ? 283 PRO C CB  1 
ATOM   11404 C CG  . PRO C 1 283 ? 145.409 179.423 95.526  1.00 57.67  ? 283 PRO C CG  1 
ATOM   11405 C CD  . PRO C 1 283 ? 143.942 179.353 95.926  1.00 57.53  ? 283 PRO C CD  1 
ATOM   11406 N N   . THR C 1 284 ? 145.640 180.497 98.942  1.00 58.52  ? 284 THR C N   1 
ATOM   11407 C CA  . THR C 1 284 ? 146.139 181.359 100.023 1.00 59.03  ? 284 THR C CA  1 
ATOM   11408 C C   . THR C 1 284 ? 145.569 181.004 101.411 1.00 58.07  ? 284 THR C C   1 
ATOM   11409 O O   . THR C 1 284 ? 146.129 181.405 102.432 1.00 58.47  ? 284 THR C O   1 
ATOM   11410 C CB  . THR C 1 284 ? 145.891 182.834 99.655  1.00 61.76  ? 284 THR C CB  1 
ATOM   11411 O OG1 . THR C 1 284 ? 146.639 183.692 100.478 1.00 63.95  ? 284 THR C OG1 1 
ATOM   11412 C CG2 . THR C 1 284 ? 144.433 183.281 99.766  1.00 58.13  ? 284 THR C CG2 1 
ATOM   11413 N N   . VAL C 1 285 ? 144.477 180.235 101.486 1.00 54.61  ? 285 VAL C N   1 
ATOM   11414 C CA  . VAL C 1 285 ? 143.732 179.979 102.730 1.00 52.48  ? 285 VAL C CA  1 
ATOM   11415 C C   . VAL C 1 285 ? 144.038 178.599 103.306 1.00 52.63  ? 285 VAL C C   1 
ATOM   11416 O O   . VAL C 1 285 ? 143.864 177.572 102.652 1.00 53.61  ? 285 VAL C O   1 
ATOM   11417 C CB  . VAL C 1 285 ? 142.215 180.144 102.531 1.00 53.07  ? 285 VAL C CB  1 
ATOM   11418 C CG1 . VAL C 1 285 ? 141.462 179.947 103.847 1.00 52.30  ? 285 VAL C CG1 1 
ATOM   11419 C CG2 . VAL C 1 285 ? 141.875 181.536 102.004 1.00 52.40  ? 285 VAL C CG2 1 
ATOM   11420 N N   . GLN C 1 286 ? 144.442 178.577 104.575 1.00 51.26  ? 286 GLN C N   1 
ATOM   11421 C CA  . GLN C 1 286 ? 144.578 177.373 105.389 1.00 49.21  ? 286 GLN C CA  1 
ATOM   11422 C C   . GLN C 1 286 ? 143.214 176.980 105.988 1.00 47.29  ? 286 GLN C C   1 
ATOM   11423 O O   . GLN C 1 286 ? 142.847 177.431 107.071 1.00 47.30  ? 286 GLN C O   1 
ATOM   11424 C CB  . GLN C 1 286 ? 145.620 177.642 106.488 1.00 50.01  ? 286 GLN C CB  1 
ATOM   11425 C CG  . GLN C 1 286 ? 147.049 177.873 105.974 1.00 49.38  ? 286 GLN C CG  1 
ATOM   11426 C CD  . GLN C 1 286 ? 147.784 176.562 105.723 1.00 56.44  ? 286 GLN C CD  1 
ATOM   11427 O OE1 . GLN C 1 286 ? 147.845 176.051 104.615 1.00 55.17  ? 286 GLN C OE1 1 
ATOM   11428 N NE2 . GLN C 1 286 ? 148.359 175.966 106.742 1.00 54.56  ? 286 GLN C NE2 1 
ATOM   11429 N N   . LEU C 1 287 ? 142.439 176.138 105.297 1.00 41.88  ? 287 LEU C N   1 
ATOM   11430 C CA  . LEU C 1 287 ? 141.070 175.784 105.713 1.00 36.66  ? 287 LEU C CA  1 
ATOM   11431 C C   . LEU C 1 287 ? 140.997 175.071 107.072 1.00 42.31  ? 287 LEU C C   1 
ATOM   11432 O O   . LEU C 1 287 ? 140.031 175.236 107.809 1.00 43.55  ? 287 LEU C O   1 
ATOM   11433 C CB  . LEU C 1 287 ? 140.413 174.896 104.646 1.00 38.54  ? 287 LEU C CB  1 
ATOM   11434 C CG  . LEU C 1 287 ? 140.181 175.549 103.278 1.00 40.81  ? 287 LEU C CG  1 
ATOM   11435 C CD1 . LEU C 1 287 ? 139.612 174.501 102.330 1.00 38.96  ? 287 LEU C CD1 1 
ATOM   11436 C CD2 . LEU C 1 287 ? 139.196 176.709 103.347 1.00 41.07  ? 287 LEU C CD2 1 
ATOM   11437 N N   . GLU C 1 288 ? 142.024 174.309 107.434 1.00 39.27  ? 288 GLU C N   1 
ATOM   11438 C CA  . GLU C 1 288 ? 142.117 173.637 108.733 1.00 29.86  ? 288 GLU C CA  1 
ATOM   11439 C C   . GLU C 1 288 ? 142.581 174.544 109.878 1.00 35.20  ? 288 GLU C C   1 
ATOM   11440 O O   . GLU C 1 288 ? 142.611 174.103 111.019 1.00 44.90  ? 288 GLU C O   1 
ATOM   11441 C CB  . GLU C 1 288 ? 143.066 172.446 108.648 1.00 35.90  ? 288 GLU C CB  1 
ATOM   11442 C CG  . GLU C 1 288 ? 142.626 171.420 107.618 1.00 31.43  ? 288 GLU C CG  1 
ATOM   11443 C CD  . GLU C 1 288 ? 143.418 170.133 107.799 1.00 40.78  ? 288 GLU C CD  1 
ATOM   11444 O OE1 . GLU C 1 288 ? 144.665 170.180 107.763 1.00 47.11  ? 288 GLU C OE1 1 
ATOM   11445 O OE2 . GLU C 1 288 ? 142.807 169.061 107.975 1.00 38.59  ? 288 GLU C OE2 1 
ATOM   11446 N N   . GLU C 1 289 ? 142.965 175.793 109.619 1.00 38.07  ? 289 GLU C N   1 
ATOM   11447 C CA  . GLU C 1 289 ? 143.296 176.764 110.672 1.00 40.72  ? 289 GLU C CA  1 
ATOM   11448 C C   . GLU C 1 289 ? 142.095 177.630 111.074 1.00 43.23  ? 289 GLU C C   1 
ATOM   11449 O O   . GLU C 1 289 ? 142.168 178.369 112.054 1.00 48.39  ? 289 GLU C O   1 
ATOM   11450 C CB  . GLU C 1 289 ? 144.486 177.638 110.255 1.00 44.13  ? 289 GLU C CB  1 
ATOM   11451 C CG  . GLU C 1 289 ? 145.790 176.834 110.192 1.00 43.46  ? 289 GLU C CG  1 
ATOM   11452 C CD  . GLU C 1 289 ? 147.018 177.701 109.860 1.00 51.38  ? 289 GLU C CD  1 
ATOM   11453 O OE1 . GLU C 1 289 ? 147.055 178.893 110.236 1.00 50.78  ? 289 GLU C OE1 1 
ATOM   11454 O OE2 . GLU C 1 289 ? 147.960 177.176 109.233 1.00 54.53  ? 289 GLU C OE2 1 
ATOM   11455 N N   . ILE C 1 290 ? 140.979 177.541 110.345 1.00 42.16  ? 290 ILE C N   1 
ATOM   11456 C CA  . ILE C 1 290 ? 139.737 178.237 110.679 1.00 35.38  ? 290 ILE C CA  1 
ATOM   11457 C C   . ILE C 1 290 ? 139.170 177.642 111.972 1.00 33.93  ? 290 ILE C C   1 
ATOM   11458 O O   . ILE C 1 290 ? 138.953 176.437 112.071 1.00 39.00  ? 290 ILE C O   1 
ATOM   11459 C CB  . ILE C 1 290 ? 138.726 178.173 109.509 1.00 37.21  ? 290 ILE C CB  1 
ATOM   11460 C CG1 . ILE C 1 290 ? 139.308 178.829 108.239 1.00 33.88  ? 290 ILE C CG1 1 
ATOM   11461 C CG2 . ILE C 1 290 ? 137.410 178.863 109.908 1.00 36.23  ? 290 ILE C CG2 1 
ATOM   11462 C CD1 . ILE C 1 290 ? 138.497 178.589 106.970 1.00 36.59  ? 290 ILE C CD1 1 
ATOM   11463 N N   . SER C 1 291 ? 138.900 178.491 112.963 1.00 33.53  ? 291 SER C N   1 
ATOM   11464 C CA  . SER C 1 291 ? 138.302 178.096 114.238 1.00 27.98  ? 291 SER C CA  1 
ATOM   11465 C C   . SER C 1 291 ? 136.811 178.411 114.277 1.00 36.38  ? 291 SER C C   1 
ATOM   11466 O O   . SER C 1 291 ? 136.391 179.496 113.877 1.00 44.46  ? 291 SER C O   1 
ATOM   11467 C CB  . SER C 1 291 ? 139.007 178.776 115.408 1.00 28.48  ? 291 SER C CB  1 
ATOM   11468 O OG  . SER C 1 291 ? 140.308 178.259 115.547 1.00 37.22  ? 291 SER C OG  1 
ATOM   11469 N N   . ASN C 1 292 ? 136.002 177.483 114.770 1.00 31.91  ? 292 ASN C N   1 
ATOM   11470 C CA  . ASN C 1 292 ? 134.590 177.734 115.052 1.00 32.35  ? 292 ASN C CA  1 
ATOM   11471 C C   . ASN C 1 292 ? 134.404 178.639 116.294 1.00 29.53  ? 292 ASN C C   1 
ATOM   11472 O O   . ASN C 1 292 ? 135.377 179.084 116.904 1.00 39.16  ? 292 ASN C O   1 
ATOM   11473 C CB  . ASN C 1 292 ? 133.846 176.386 115.096 1.00 26.06  ? 292 ASN C CB  1 
ATOM   11474 C CG  . ASN C 1 292 ? 134.084 175.536 116.319 1.00 25.93  ? 292 ASN C CG  1 
ATOM   11475 O OD1 . ASN C 1 292 ? 134.708 175.937 117.285 1.00 33.55  ? 292 ASN C OD1 1 
ATOM   11476 N ND2 . ASN C 1 292 ? 133.564 174.345 116.329 1.00 28.64  ? 292 ASN C ND2 1 
ATOM   11477 N N   . HIS C 1 293 ? 133.169 178.933 116.703 1.00 34.59  ? 293 HIS C N   1 
ATOM   11478 C CA  . HIS C 1 293 ? 132.903 179.814 117.857 1.00 35.06  ? 293 HIS C CA  1 
ATOM   11479 C C   . HIS C 1 293 ? 133.394 179.262 119.201 1.00 33.97  ? 293 HIS C C   1 
ATOM   11480 O O   . HIS C 1 293 ? 133.623 180.035 120.126 1.00 40.06  ? 293 HIS C O   1 
ATOM   11481 C CB  . HIS C 1 293 ? 131.404 180.137 117.929 1.00 33.07  ? 293 HIS C CB  1 
ATOM   11482 C CG  . HIS C 1 293 ? 130.854 180.903 116.752 1.00 34.90  ? 293 HIS C CG  1 
ATOM   11483 N ND1 . HIS C 1 293 ? 129.499 181.103 116.503 1.00 42.46  ? 293 HIS C ND1 1 
ATOM   11484 C CD2 . HIS C 1 293 ? 131.572 181.560 115.796 1.00 34.43  ? 293 HIS C CD2 1 
ATOM   11485 C CE1 . HIS C 1 293 ? 129.427 181.849 115.391 1.00 40.23  ? 293 HIS C CE1 1 
ATOM   11486 N NE2 . HIS C 1 293 ? 130.659 182.135 114.947 1.00 36.34  ? 293 HIS C NE2 1 
ATOM   11487 N N   . GLN C 1 294 ? 133.598 177.946 119.322 1.00 37.59  ? 294 GLN C N   1 
ATOM   11488 C CA  . GLN C 1 294 ? 134.238 177.311 120.480 1.00 37.26  ? 294 GLN C CA  1 
ATOM   11489 C C   . GLN C 1 294 ? 135.781 177.376 120.441 1.00 41.81  ? 294 GLN C C   1 
ATOM   11490 O O   . GLN C 1 294 ? 136.442 176.841 121.329 1.00 43.28  ? 294 GLN C O   1 
ATOM   11491 C CB  . GLN C 1 294 ? 133.751 175.861 120.637 1.00 36.68  ? 294 GLN C CB  1 
ATOM   11492 C CG  . GLN C 1 294 ? 132.237 175.759 120.841 1.00 41.30  ? 294 GLN C CG  1 
ATOM   11493 C CD  . GLN C 1 294 ? 131.751 174.351 121.181 1.00 48.68  ? 294 GLN C CD  1 
ATOM   11494 O OE1 . GLN C 1 294 ? 132.506 173.444 121.505 1.00 49.02  ? 294 GLN C OE1 1 
ATOM   11495 N NE2 . GLN C 1 294 ? 130.462 174.113 121.139 1.00 44.33  ? 294 GLN C NE2 1 
ATOM   11496 N N   . GLY C 1 295 ? 136.373 178.003 119.418 1.00 38.61  ? 295 GLY C N   1 
ATOM   11497 C CA  . GLY C 1 295 ? 137.819 178.104 119.235 1.00 33.27  ? 295 GLY C CA  1 
ATOM   11498 C C   . GLY C 1 295 ? 138.473 176.824 118.710 1.00 38.98  ? 295 GLY C C   1 
ATOM   11499 O O   . GLY C 1 295 ? 139.667 176.625 118.911 1.00 44.31  ? 295 GLY C O   1 
ATOM   11500 N N   . LEU C 1 296 ? 137.710 175.937 118.071 1.00 33.55  ? 296 LEU C N   1 
ATOM   11501 C CA  . LEU C 1 296 ? 138.192 174.641 117.598 1.00 24.93  ? 296 LEU C CA  1 
ATOM   11502 C C   . LEU C 1 296 ? 138.402 174.658 116.084 1.00 22.90  ? 296 LEU C C   1 
ATOM   11503 O O   . LEU C 1 296 ? 137.520 175.041 115.323 1.00 31.16  ? 296 LEU C O   1 
ATOM   11504 C CB  . LEU C 1 296 ? 137.208 173.529 117.994 1.00 24.38  ? 296 LEU C CB  1 
ATOM   11505 C CG  . LEU C 1 296 ? 136.919 173.422 119.498 1.00 25.97  ? 296 LEU C CG  1 
ATOM   11506 C CD1 . LEU C 1 296 ? 135.712 172.527 119.714 1.00 30.68  ? 296 LEU C CD1 1 
ATOM   11507 C CD2 . LEU C 1 296 ? 138.083 172.832 120.276 1.00 23.43  ? 296 LEU C CD2 1 
ATOM   11508 N N   . THR C 1 297 ? 139.561 174.197 115.633 1.00 29.86  ? 297 THR C N   1 
ATOM   11509 C CA  . THR C 1 297 ? 139.803 173.778 114.250 1.00 24.33  ? 297 THR C CA  1 
ATOM   11510 C C   . THR C 1 297 ? 139.196 172.390 113.997 1.00 20.55  ? 297 THR C C   1 
ATOM   11511 O O   . THR C 1 297 ? 138.845 171.711 114.961 1.00 31.00  ? 297 THR C O   1 
ATOM   11512 C CB  . THR C 1 297 ? 141.309 173.749 113.976 1.00 27.18  ? 297 THR C CB  1 
ATOM   11513 O OG1 . THR C 1 297 ? 141.959 172.820 114.808 1.00 33.94  ? 297 THR C OG1 1 
ATOM   11514 C CG2 . THR C 1 297 ? 141.971 175.102 114.186 1.00 20.54  ? 297 THR C CG2 1 
ATOM   11515 N N   . PRO C 1 298 ? 139.066 171.902 112.751 1.00 18.71  ? 298 PRO C N   1 
ATOM   11516 C CA  . PRO C 1 298 ? 138.537 170.560 112.501 1.00 17.52  ? 298 PRO C CA  1 
ATOM   11517 C C   . PRO C 1 298 ? 139.265 169.426 113.251 1.00 17.44  ? 298 PRO C C   1 
ATOM   11518 O O   . PRO C 1 298 ? 138.606 168.534 113.769 1.00 22.84  ? 298 PRO C O   1 
ATOM   11519 C CB  . PRO C 1 298 ? 138.610 170.389 110.989 1.00 20.19  ? 298 PRO C CB  1 
ATOM   11520 C CG  . PRO C 1 298 ? 138.513 171.810 110.450 1.00 10.15  ? 298 PRO C CG  1 
ATOM   11521 C CD  . PRO C 1 298 ? 139.256 172.621 111.498 1.00 14.12  ? 298 PRO C CD  1 
ATOM   11522 N N   . LEU C 1 299 ? 140.597 169.475 113.399 1.00 17.48  ? 299 LEU C N   1 
ATOM   11523 C CA  . LEU C 1 299 ? 141.367 168.493 114.181 1.00 13.01  ? 299 LEU C CA  1 
ATOM   11524 C C   . LEU C 1 299 ? 141.075 168.564 115.688 1.00 22.21  ? 299 LEU C C   1 
ATOM   11525 O O   . LEU C 1 299 ? 140.902 167.537 116.336 1.00 22.81  ? 299 LEU C O   1 
ATOM   11526 C CB  . LEU C 1 299 ? 142.866 168.706 113.901 1.00 15.92  ? 299 LEU C CB  1 
ATOM   11527 C CG  . LEU C 1 299 ? 143.805 167.779 114.691 1.00 18.92  ? 299 LEU C CG  1 
ATOM   11528 C CD1 . LEU C 1 299 ? 143.669 166.312 114.307 1.00 16.51  ? 299 LEU C CD1 1 
ATOM   11529 C CD2 . LEU C 1 299 ? 145.250 168.202 114.486 1.00 17.57  ? 299 LEU C CD2 1 
ATOM   11530 N N   . LYS C 1 300 ? 140.980 169.772 116.249 1.00 23.63  ? 300 LYS C N   1 
ATOM   11531 C CA  . LYS C 1 300 ? 140.598 169.996 117.649 1.00 8.45   ? 300 LYS C CA  1 
ATOM   11532 C C   . LYS C 1 300 ? 139.155 169.586 117.930 1.00 18.42  ? 300 LYS C C   1 
ATOM   11533 O O   . LYS C 1 300 ? 138.877 169.025 118.980 1.00 19.93  ? 300 LYS C O   1 
ATOM   11534 C CB  . LYS C 1 300 ? 140.830 171.464 118.013 1.00 21.30  ? 300 LYS C CB  1 
ATOM   11535 C CG  . LYS C 1 300 ? 142.314 171.820 118.128 1.00 19.51  ? 300 LYS C CG  1 
ATOM   11536 C CD  . LYS C 1 300 ? 142.479 173.256 118.632 1.00 19.44  ? 300 LYS C CD  1 
ATOM   11537 C CE  . LYS C 1 300 ? 143.949 173.664 118.603 1.00 21.92  ? 300 LYS C CE  1 
ATOM   11538 N NZ  . LYS C 1 300 ? 144.165 174.984 119.241 1.00 30.28  ? 300 LYS C NZ  1 
ATOM   11539 N N   . LEU C 1 301 ? 138.237 169.814 116.993 1.00 25.60  ? 301 LEU C N   1 
ATOM   11540 C CA  . LEU C 1 301 ? 136.865 169.324 117.067 1.00 10.90  ? 301 LEU C CA  1 
ATOM   11541 C C   . LEU C 1 301 ? 136.792 167.796 116.960 1.00 17.34  ? 301 LEU C C   1 
ATOM   11542 O O   . LEU C 1 301 ? 136.042 167.178 117.704 1.00 26.60  ? 301 LEU C O   1 
ATOM   11543 C CB  . LEU C 1 301 ? 136.039 170.037 115.989 1.00 28.60  ? 301 LEU C CB  1 
ATOM   11544 C CG  . LEU C 1 301 ? 134.540 169.703 116.038 1.00 25.01  ? 301 LEU C CG  1 
ATOM   11545 C CD1 . LEU C 1 301 ? 133.879 170.275 117.282 1.00 22.47  ? 301 LEU C CD1 1 
ATOM   11546 C CD2 . LEU C 1 301 ? 133.848 170.292 114.821 1.00 18.00  ? 301 LEU C CD2 1 
ATOM   11547 N N   . ALA C 1 302 ? 137.599 167.160 116.111 1.00 21.02  ? 302 ALA C N   1 
ATOM   11548 C CA  . ALA C 1 302 ? 137.660 165.703 116.036 1.00 21.88  ? 302 ALA C CA  1 
ATOM   11549 C C   . ALA C 1 302 ? 138.173 165.086 117.346 1.00 18.90  ? 302 ALA C C   1 
ATOM   11550 O O   . ALA C 1 302 ? 137.607 164.112 117.828 1.00 21.27  ? 302 ALA C O   1 
ATOM   11551 C CB  . ALA C 1 302 ? 138.501 165.291 114.824 1.00 12.83  ? 302 ALA C CB  1 
ATOM   11552 N N   . ALA C 1 303 ? 139.177 165.703 117.977 1.00 22.88  ? 303 ALA C N   1 
ATOM   11553 C CA  . ALA C 1 303 ? 139.639 165.354 119.315 1.00 15.38  ? 303 ALA C CA  1 
ATOM   11554 C C   . ALA C 1 303 ? 138.564 165.582 120.396 1.00 24.60  ? 303 ALA C C   1 
ATOM   11555 O O   . ALA C 1 303 ? 138.332 164.704 121.218 1.00 29.84  ? 303 ALA C O   1 
ATOM   11556 C CB  . ALA C 1 303 ? 140.900 166.165 119.611 1.00 24.93  ? 303 ALA C CB  1 
ATOM   11557 N N   . LYS C 1 304 ? 137.868 166.726 120.408 1.00 29.96  ? 304 LYS C N   1 
ATOM   11558 C CA  . LYS C 1 304 ? 136.849 167.029 121.420 1.00 20.38  ? 304 LYS C CA  1 
ATOM   11559 C C   . LYS C 1 304 ? 135.654 166.093 121.342 1.00 18.54  ? 304 LYS C C   1 
ATOM   11560 O O   . LYS C 1 304 ? 135.204 165.570 122.355 1.00 32.35  ? 304 LYS C O   1 
ATOM   11561 C CB  . LYS C 1 304 ? 136.402 168.492 121.311 1.00 21.09  ? 304 LYS C CB  1 
ATOM   11562 C CG  . LYS C 1 304 ? 135.520 168.857 122.509 1.00 30.04  ? 304 LYS C CG  1 
ATOM   11563 C CD  . LYS C 1 304 ? 135.089 170.316 122.470 1.00 34.83  ? 304 LYS C CD  1 
ATOM   11564 C CE  . LYS C 1 304 ? 134.153 170.615 123.640 1.00 34.85  ? 304 LYS C CE  1 
ATOM   11565 N NZ  . LYS C 1 304 ? 133.720 172.032 123.646 1.00 36.77  ? 304 LYS C NZ  1 
ATOM   11566 N N   . GLU C 1 305 ? 135.139 165.861 120.145 1.00 28.13  ? 305 GLU C N   1 
ATOM   11567 C CA  . GLU C 1 305 ? 133.951 165.043 119.915 1.00 21.07  ? 305 GLU C CA  1 
ATOM   11568 C C   . GLU C 1 305 ? 134.254 163.536 119.843 1.00 25.61  ? 305 GLU C C   1 
ATOM   11569 O O   . GLU C 1 305 ? 133.351 162.740 119.604 1.00 33.40  ? 305 GLU C O   1 
ATOM   11570 C CB  . GLU C 1 305 ? 133.215 165.564 118.674 1.00 21.28  ? 305 GLU C CB  1 
ATOM   11571 C CG  . GLU C 1 305 ? 132.790 167.040 118.734 1.00 25.37  ? 305 GLU C CG  1 
ATOM   11572 C CD  . GLU C 1 305 ? 131.886 167.394 119.924 1.00 32.00  ? 305 GLU C CD  1 
ATOM   11573 O OE1 . GLU C 1 305 ? 131.171 166.504 120.440 1.00 36.97  ? 305 GLU C OE1 1 
ATOM   11574 O OE2 . GLU C 1 305 ? 131.866 168.571 120.336 1.00 36.71  ? 305 GLU C OE2 1 
ATOM   11575 N N   . GLY C 1 306 ? 135.504 163.121 120.059 1.00 11.72  ? 306 GLY C N   1 
ATOM   11576 C CA  . GLY C 1 306 ? 135.914 161.717 120.099 1.00 9.37   ? 306 GLY C CA  1 
ATOM   11577 C C   . GLY C 1 306 ? 135.843 160.994 118.757 1.00 19.24  ? 306 GLY C C   1 
ATOM   11578 O O   . GLY C 1 306 ? 135.588 159.793 118.716 1.00 30.45  ? 306 GLY C O   1 
ATOM   11579 N N   . LYS C 1 307 ? 136.011 161.713 117.643 1.00 27.57  ? 307 LYS C N   1 
ATOM   11580 C CA  . LYS C 1 307 ? 135.849 161.186 116.283 1.00 22.61  ? 307 LYS C CA  1 
ATOM   11581 C C   . LYS C 1 307 ? 137.143 160.531 115.827 1.00 20.17  ? 307 LYS C C   1 
ATOM   11582 O O   . LYS C 1 307 ? 137.854 161.057 114.985 1.00 23.49  ? 307 LYS C O   1 
ATOM   11583 C CB  . LYS C 1 307 ? 135.355 162.295 115.338 1.00 18.76  ? 307 LYS C CB  1 
ATOM   11584 C CG  . LYS C 1 307 ? 134.109 163.033 115.824 1.00 13.17  ? 307 LYS C CG  1 
ATOM   11585 C CD  . LYS C 1 307 ? 132.959 162.082 116.167 1.00 17.47  ? 307 LYS C CD  1 
ATOM   11586 C CE  . LYS C 1 307 ? 131.656 162.822 116.466 1.00 24.71  ? 307 LYS C CE  1 
ATOM   11587 N NZ  . LYS C 1 307 ? 130.974 163.291 115.239 1.00 21.56  ? 307 LYS C NZ  1 
ATOM   11588 N N   . ILE C 1 308 ? 137.494 159.414 116.447 1.00 24.81  ? 308 ILE C N   1 
ATOM   11589 C CA  . ILE C 1 308 ? 138.833 158.830 116.381 1.00 27.76  ? 308 ILE C CA  1 
ATOM   11590 C C   . ILE C 1 308 ? 139.283 158.455 114.966 1.00 25.90  ? 308 ILE C C   1 
ATOM   11591 O O   . ILE C 1 308 ? 140.461 158.582 114.649 1.00 30.17  ? 308 ILE C O   1 
ATOM   11592 C CB  . ILE C 1 308 ? 138.958 157.662 117.380 1.00 33.40  ? 308 ILE C CB  1 
ATOM   11593 C CG1 . ILE C 1 308 ? 140.407 157.151 117.374 1.00 35.40  ? 308 ILE C CG1 1 
ATOM   11594 C CG2 . ILE C 1 308 ? 137.967 156.523 117.106 1.00 25.71  ? 308 ILE C CG2 1 
ATOM   11595 C CD1 . ILE C 1 308 ? 140.738 156.256 118.554 1.00 26.87  ? 308 ILE C CD1 1 
ATOM   11596 N N   . GLU C 1 309 ? 138.376 158.026 114.094 1.00 33.00  ? 309 GLU C N   1 
ATOM   11597 C CA  . GLU C 1 309 ? 138.727 157.599 112.740 1.00 31.64  ? 309 GLU C CA  1 
ATOM   11598 C C   . GLU C 1 309 ? 139.143 158.779 111.843 1.00 28.67  ? 309 GLU C C   1 
ATOM   11599 O O   . GLU C 1 309 ? 140.195 158.729 111.210 1.00 33.10  ? 309 GLU C O   1 
ATOM   11600 C CB  . GLU C 1 309 ? 137.561 156.804 112.143 1.00 34.52  ? 309 GLU C CB  1 
ATOM   11601 C CG  . GLU C 1 309 ? 137.172 155.569 112.977 1.00 29.62  ? 309 GLU C CG  1 
ATOM   11602 C CD  . GLU C 1 309 ? 138.325 154.570 113.116 1.00 39.76  ? 309 GLU C CD  1 
ATOM   11603 O OE1 . GLU C 1 309 ? 138.976 154.255 112.097 1.00 38.84  ? 309 GLU C OE1 1 
ATOM   11604 O OE2 . GLU C 1 309 ? 138.637 154.113 114.238 1.00 42.35  ? 309 GLU C OE2 1 
ATOM   11605 N N   . ILE C 1 310 ? 138.380 159.875 111.837 1.00 20.17  ? 310 ILE C N   1 
ATOM   11606 C CA  . ILE C 1 310 ? 138.759 161.111 111.134 1.00 17.68  ? 310 ILE C CA  1 
ATOM   11607 C C   . ILE C 1 310 ? 139.880 161.864 111.862 1.00 21.24  ? 310 ILE C C   1 
ATOM   11608 O O   . ILE C 1 310 ? 140.725 162.466 111.213 1.00 34.42  ? 310 ILE C O   1 
ATOM   11609 C CB  . ILE C 1 310 ? 137.521 161.986 110.820 1.00 23.57  ? 310 ILE C CB  1 
ATOM   11610 C CG1 . ILE C 1 310 ? 137.819 163.238 109.969 1.00 31.86  ? 310 ILE C CG1 1 
ATOM   11611 C CG2 . ILE C 1 310 ? 136.805 162.470 112.083 1.00 20.72  ? 310 ILE C CG2 1 
ATOM   11612 C CD1 . ILE C 1 310 ? 138.428 162.947 108.598 1.00 28.47  ? 310 ILE C CD1 1 
ATOM   11613 N N   . PHE C 1 311 ? 139.962 161.779 113.189 1.00 25.94  ? 311 PHE C N   1 
ATOM   11614 C CA  . PHE C 1 311 ? 141.066 162.323 113.973 1.00 16.36  ? 311 PHE C CA  1 
ATOM   11615 C C   . PHE C 1 311 ? 142.398 161.667 113.599 1.00 19.12  ? 311 PHE C C   1 
ATOM   11616 O O   . PHE C 1 311 ? 143.323 162.371 113.213 1.00 23.88  ? 311 PHE C O   1 
ATOM   11617 C CB  . PHE C 1 311 ? 140.755 162.159 115.466 1.00 17.49  ? 311 PHE C CB  1 
ATOM   11618 C CG  . PHE C 1 311 ? 141.879 162.574 116.381 1.00 14.11  ? 311 PHE C CG  1 
ATOM   11619 C CD1 . PHE C 1 311 ? 142.169 163.935 116.551 1.00 16.57  ? 311 PHE C CD1 1 
ATOM   11620 C CD2 . PHE C 1 311 ? 142.664 161.604 117.029 1.00 13.75  ? 311 PHE C CD2 1 
ATOM   11621 C CE1 . PHE C 1 311 ? 143.267 164.326 117.322 1.00 18.21  ? 311 PHE C CE1 1 
ATOM   11622 C CE2 . PHE C 1 311 ? 143.747 161.999 117.826 1.00 16.90  ? 311 PHE C CE2 1 
ATOM   11623 C CZ  . PHE C 1 311 ? 144.058 163.356 117.954 1.00 22.51  ? 311 PHE C CZ  1 
ATOM   11624 N N   . ARG C 1 312 ? 142.477 160.329 113.614 1.00 19.19  ? 312 ARG C N   1 
ATOM   11625 C CA  . ARG C 1 312 ? 143.646 159.569 113.161 1.00 12.33  ? 312 ARG C CA  1 
ATOM   11626 C C   . ARG C 1 312 ? 144.006 159.913 111.724 1.00 27.71  ? 312 ARG C C   1 
ATOM   11627 O O   . ARG C 1 312 ? 145.174 160.136 111.434 1.00 34.01  ? 312 ARG C O   1 
ATOM   11628 C CB  . ARG C 1 312 ? 143.366 158.064 113.279 1.00 21.53  ? 312 ARG C CB  1 
ATOM   11629 C CG  . ARG C 1 312 ? 144.625 157.220 113.042 1.00 23.09  ? 312 ARG C CG  1 
ATOM   11630 C CD  . ARG C 1 312 ? 144.341 155.737 112.796 1.00 28.73  ? 312 ARG C CD  1 
ATOM   11631 N NE  . ARG C 1 312 ? 143.416 155.155 113.787 1.00 37.09  ? 312 ARG C NE  1 
ATOM   11632 C CZ  . ARG C 1 312 ? 142.154 154.817 113.584 1.00 36.45  ? 312 ARG C CZ  1 
ATOM   11633 N NH1 . ARG C 1 312 ? 141.415 154.408 114.567 1.00 30.38  ? 312 ARG C NH1 1 
ATOM   11634 N NH2 . ARG C 1 312 ? 141.609 154.882 112.411 1.00 29.65  ? 312 ARG C NH2 1 
ATOM   11635 N N   . HIS C 1 313 ? 143.012 159.980 110.838 1.00 25.52  ? 313 HIS C N   1 
ATOM   11636 C CA  . HIS C 1 313 ? 143.234 160.323 109.448 1.00 23.12  ? 313 HIS C CA  1 
ATOM   11637 C C   . HIS C 1 313 ? 143.882 161.695 109.298 1.00 23.51  ? 313 HIS C C   1 
ATOM   11638 O O   . HIS C 1 313 ? 144.945 161.749 108.650 1.00 32.28  ? 313 HIS C O   1 
ATOM   11639 C CB  . HIS C 1 313 ? 141.898 160.272 108.692 1.00 25.43  ? 313 HIS C CB  1 
ATOM   11640 C CG  . HIS C 1 313 ? 141.892 161.081 107.441 1.00 37.42  ? 313 HIS C CG  1 
ATOM   11641 N ND1 . HIS C 1 313 ? 142.450 160.623 106.264 1.00 22.71  ? 313 HIS C ND1 1 
ATOM   11642 C CD2 . HIS C 1 313 ? 141.407 162.314 107.179 1.00 39.50  ? 313 HIS C CD2 1 
ATOM   11643 C CE1 . HIS C 1 313 ? 142.306 161.539 105.329 1.00 26.56  ? 313 HIS C CE1 1 
ATOM   11644 N NE2 . HIS C 1 313 ? 141.668 162.585 105.865 1.00 37.15  ? 313 HIS C NE2 1 
ATOM   11645 N N   . ILE C 1 314 ? 143.307 162.765 109.858 1.00 19.37  ? 314 ILE C N   1 
ATOM   11646 C CA  . ILE C 1 314 ? 143.878 164.114 109.763 1.00 20.66  ? 314 ILE C CA  1 
ATOM   11647 C C   . ILE C 1 314 ? 145.293 164.103 110.361 1.00 19.02  ? 314 ILE C C   1 
ATOM   11648 O O   . ILE C 1 314 ? 146.215 164.587 109.678 1.00 29.86  ? 314 ILE C O   1 
ATOM   11649 C CB  . ILE C 1 314 ? 143.008 165.155 110.506 1.00 23.89  ? 314 ILE C CB  1 
ATOM   11650 C CG1 . ILE C 1 314 ? 141.601 165.256 109.915 1.00 23.14  ? 314 ILE C CG1 1 
ATOM   11651 C CG2 . ILE C 1 314 ? 143.718 166.520 110.543 1.00 19.76  ? 314 ILE C CG2 1 
ATOM   11652 C CD1 . ILE C 1 314 ? 140.687 166.200 110.662 1.00 22.05  ? 314 ILE C CD1 1 
ATOM   11653 N N   . LEU C 1 315 ? 145.459 163.570 111.576 1.00 23.75  ? 315 LEU C N   1 
ATOM   11654 C CA  . LEU C 1 315 ? 146.765 163.613 112.301 1.00 25.28  ? 315 LEU C CA  1 
ATOM   11655 C C   . LEU C 1 315 ? 147.883 162.880 111.550 1.00 27.09  ? 315 LEU C C   1 
ATOM   11656 O O   . LEU C 1 315 ? 149.018 163.343 111.617 1.00 25.44  ? 315 LEU C O   1 
ATOM   11657 C CB  . LEU C 1 315 ? 146.533 162.974 113.674 1.00 24.64  ? 315 LEU C CB  1 
ATOM   11658 C CG  . LEU C 1 315 ? 147.760 162.857 114.574 1.00 35.98  ? 315 LEU C CG  1 
ATOM   11659 C CD1 . LEU C 1 315 ? 148.226 164.232 115.028 1.00 32.44  ? 315 LEU C CD1 1 
ATOM   11660 C CD2 . LEU C 1 315 ? 147.451 161.976 115.774 1.00 25.32  ? 315 LEU C CD2 1 
ATOM   11661 N N   . GLN C 1 316 ? 147.606 161.797 110.826 1.00 33.59  ? 316 GLN C N   1 
ATOM   11662 C CA  . GLN C 1 316 ? 148.586 160.967 110.124 1.00 26.49  ? 316 GLN C CA  1 
ATOM   11663 C C   . GLN C 1 316 ? 148.580 161.142 108.593 1.00 21.29  ? 316 GLN C C   1 
ATOM   11664 O O   . GLN C 1 316 ? 149.148 160.317 107.878 1.00 32.62  ? 316 GLN C O   1 
ATOM   11665 C CB  . GLN C 1 316 ? 148.385 159.498 110.526 1.00 20.24  ? 316 GLN C CB  1 
ATOM   11666 C CG  . GLN C 1 316 ? 148.370 159.281 112.046 1.00 30.59  ? 316 GLN C CG  1 
ATOM   11667 C CD  . GLN C 1 316 ? 148.197 157.831 112.450 1.00 29.59  ? 316 GLN C CD  1 
ATOM   11668 O OE1 . GLN C 1 316 ? 147.869 156.952 111.668 1.00 32.37  ? 316 GLN C OE1 1 
ATOM   11669 N NE2 . GLN C 1 316 ? 148.397 157.530 113.708 1.00 24.62  ? 316 GLN C NE2 1 
ATOM   11670 N N   . ARG C 1 317 ? 147.896 162.179 108.090 1.00 22.22  ? 317 ARG C N   1 
ATOM   11671 C CA  . ARG C 1 317 ? 147.678 162.372 106.621 1.00 33.27  ? 317 ARG C CA  1 
ATOM   11672 C C   . ARG C 1 317 ? 148.961 162.634 105.827 1.00 30.60  ? 317 ARG C C   1 
ATOM   11673 O O   . ARG C 1 317 ? 149.771 163.468 106.275 1.00 32.73  ? 317 ARG C O   1 
ATOM   11674 C CB  . ARG C 1 317 ? 146.705 163.542 106.480 1.00 29.30  ? 317 ARG C CB  1 
ATOM   11675 C CG  . ARG C 1 317 ? 146.140 163.705 105.072 1.00 25.10  ? 317 ARG C CG  1 
ATOM   11676 C CD  . ARG C 1 317 ? 145.072 164.797 105.091 1.00 35.92  ? 317 ARG C CD  1 
ATOM   11677 N NE  . ARG C 1 317 ? 145.620 166.124 105.335 1.00 34.36  ? 317 ARG C NE  1 
ATOM   11678 C CZ  . ARG C 1 317 ? 145.724 166.689 106.533 1.00 28.56  ? 317 ARG C CZ  1 
ATOM   11679 N NH1 . ARG C 1 317 ? 146.235 167.901 106.653 1.00 30.45  ? 317 ARG C NH1 1 
ATOM   11680 N NH2 . ARG C 1 317 ? 145.313 166.039 107.608 1.00 40.48  ? 317 ARG C NH2 1 
ATOM   11681 N N   . GLU C 1 318 ? 149.132 161.947 104.694 1.00 34.63  ? 318 GLU C N   1 
ATOM   11682 C CA  . GLU C 1 318 ? 150.248 162.152 103.765 1.00 30.10  ? 318 GLU C CA  1 
ATOM   11683 C C   . GLU C 1 318 ? 149.806 162.162 102.291 1.00 36.37  ? 318 GLU C C   1 
ATOM   11684 O O   . GLU C 1 318 ? 148.958 161.369 101.887 1.00 38.19  ? 318 GLU C O   1 
ATOM   11685 C CB  . GLU C 1 318 ? 151.343 161.107 104.038 1.00 36.17  ? 318 GLU C CB  1 
ATOM   11686 C CG  . GLU C 1 318 ? 152.595 161.365 103.190 1.00 38.84  ? 318 GLU C CG  1 
ATOM   11687 C CD  . GLU C 1 318 ? 153.835 160.590 103.658 1.00 42.73  ? 318 GLU C CD  1 
ATOM   11688 O OE1 . GLU C 1 318 ? 153.694 159.541 104.325 1.00 46.32  ? 318 GLU C OE1 1 
ATOM   11689 O OE2 . GLU C 1 318 ? 154.956 161.008 103.298 1.00 38.33  ? 318 GLU C OE2 1 
ATOM   11690 N N   . PHE C 1 319 ? 150.416 163.035 101.483 1.00 44.55  ? 319 PHE C N   1 
ATOM   11691 C CA  . PHE C 1 319 ? 150.221 163.166 100.016 1.00 37.85  ? 319 PHE C CA  1 
ATOM   11692 C C   . PHE C 1 319 ? 151.569 163.432 99.305  1.00 46.51  ? 319 PHE C C   1 
ATOM   11693 O O   . PHE C 1 319 ? 152.570 163.700 99.998  1.00 47.26  ? 319 PHE C O   1 
ATOM   11694 C CB  . PHE C 1 319 ? 149.282 164.327 99.685  1.00 36.75  ? 319 PHE C CB  1 
ATOM   11695 C CG  . PHE C 1 319 ? 147.986 164.365 100.453 1.00 42.37  ? 319 PHE C CG  1 
ATOM   11696 C CD1 . PHE C 1 319 ? 146.967 163.471 100.171 1.00 45.23  ? 319 PHE C CD1 1 
ATOM   11697 C CD2 . PHE C 1 319 ? 147.777 165.313 101.441 1.00 41.95  ? 319 PHE C CD2 1 
ATOM   11698 C CE1 . PHE C 1 319 ? 145.772 163.513 100.871 1.00 40.34  ? 319 PHE C CE1 1 
ATOM   11699 C CE2 . PHE C 1 319 ? 146.582 165.357 102.140 1.00 40.43  ? 319 PHE C CE2 1 
ATOM   11700 C CZ  . PHE C 1 319 ? 145.581 164.457 101.853 1.00 40.88  ? 319 PHE C CZ  1 
ATOM   11701 N N   . SER C 1 320 ? 151.574 163.364 97.968  1.00 57.85  ? 320 SER C N   1 
ATOM   11702 C CA  . SER C 1 320 ? 152.750 163.530 97.087  1.00 56.28  ? 320 SER C CA  1 
ATOM   11703 C C   . SER C 1 320 ? 152.413 164.322 95.810  1.00 56.01  ? 320 SER C C   1 
ATOM   11704 O O   . SER C 1 320 ? 151.236 164.474 95.470  1.00 55.32  ? 320 SER C O   1 
ATOM   11705 C CB  . SER C 1 320 ? 153.332 162.155 96.754  1.00 53.75  ? 320 SER C CB  1 
ATOM   11706 O OG  . SER C 1 320 ? 152.375 161.342 96.106  1.00 58.82  ? 320 SER C OG  1 
ATOM   11707 N N   . GLY C 1 321 ? 153.405 164.877 95.121  1.00 57.85  ? 321 GLY C N   1 
ATOM   11708 C CA  . GLY C 1 321 ? 153.147 165.756 93.980  1.00 57.04  ? 321 GLY C CA  1 
ATOM   11709 C C   . GLY C 1 321 ? 152.483 167.068 94.420  1.00 57.26  ? 321 GLY C C   1 
ATOM   11710 O O   . GLY C 1 321 ? 152.997 167.719 95.334  1.00 58.67  ? 321 GLY C O   1 
ATOM   11711 N N   . PRO C 1 322 ? 151.359 167.491 93.814  1.00 56.12  ? 322 PRO C N   1 
ATOM   11712 C CA  . PRO C 1 322 ? 150.807 168.829 94.028  1.00 54.60  ? 322 PRO C CA  1 
ATOM   11713 C C   . PRO C 1 322 ? 150.220 169.034 95.431  1.00 53.71  ? 322 PRO C C   1 
ATOM   11714 O O   . PRO C 1 322 ? 150.233 170.144 95.955  1.00 54.93  ? 322 PRO C O   1 
ATOM   11715 C CB  . PRO C 1 322 ? 149.736 168.988 92.945  1.00 52.56  ? 322 PRO C CB  1 
ATOM   11716 C CG  . PRO C 1 322 ? 149.282 167.559 92.662  1.00 53.50  ? 322 PRO C CG  1 
ATOM   11717 C CD  . PRO C 1 322 ? 150.563 166.756 92.844  1.00 52.15  ? 322 PRO C CD  1 
ATOM   11718 N N   . TYR C 1 323 ? 149.719 167.961 96.052  1.00 48.59  ? 323 TYR C N   1 
ATOM   11719 C CA  . TYR C 1 323 ? 149.026 167.998 97.340  1.00 45.39  ? 323 TYR C CA  1 
ATOM   11720 C C   . TYR C 1 323 ? 149.922 167.728 98.550  1.00 49.38  ? 323 TYR C C   1 
ATOM   11721 O O   . TYR C 1 323 ? 149.441 167.751 99.674  1.00 49.70  ? 323 TYR C O   1 
ATOM   11722 C CB  . TYR C 1 323 ? 147.813 167.057 97.281  1.00 45.00  ? 323 TYR C CB  1 
ATOM   11723 C CG  . TYR C 1 323 ? 146.807 167.420 96.202  1.00 49.38  ? 323 TYR C CG  1 
ATOM   11724 C CD1 . TYR C 1 323 ? 146.304 168.735 96.106  1.00 48.18  ? 323 TYR C CD1 1 
ATOM   11725 C CD2 . TYR C 1 323 ? 146.371 166.438 95.294  1.00 47.60  ? 323 TYR C CD2 1 
ATOM   11726 C CE1 . TYR C 1 323 ? 145.382 169.066 95.098  1.00 46.48  ? 323 TYR C CE1 1 
ATOM   11727 C CE2 . TYR C 1 323 ? 145.440 166.764 94.293  1.00 45.79  ? 323 TYR C CE2 1 
ATOM   11728 C CZ  . TYR C 1 323 ? 144.947 168.078 94.193  1.00 50.01  ? 323 TYR C CZ  1 
ATOM   11729 O OH  . TYR C 1 323 ? 144.026 168.391 93.244  1.00 50.53  ? 323 TYR C OH  1 
ATOM   11730 N N   . GLN C 1 324 ? 151.222 167.511 98.359  1.00 48.14  ? 324 GLN C N   1 
ATOM   11731 C CA  . GLN C 1 324 ? 152.163 167.243 99.447  1.00 42.85  ? 324 GLN C CA  1 
ATOM   11732 C C   . GLN C 1 324 ? 152.103 168.272 100.601 1.00 44.68  ? 324 GLN C C   1 
ATOM   11733 O O   . GLN C 1 324 ? 152.093 167.826 101.749 1.00 43.91  ? 324 GLN C O   1 
ATOM   11734 C CB  . GLN C 1 324 ? 153.564 167.039 98.849  1.00 46.74  ? 324 GLN C CB  1 
ATOM   11735 C CG  . GLN C 1 324 ? 154.609 166.495 99.837  1.00 47.44  ? 324 GLN C CG  1 
ATOM   11736 C CD  . GLN C 1 324 ? 155.459 167.560 100.520 1.00 47.99  ? 324 GLN C CD  1 
ATOM   11737 O OE1 . GLN C 1 324 ? 155.185 168.748 100.495 1.00 50.34  ? 324 GLN C OE1 1 
ATOM   11738 N NE2 . GLN C 1 324 ? 156.537 167.165 101.151 1.00 46.16  ? 324 GLN C NE2 1 
ATOM   11739 N N   . PRO C 1 325 ? 151.938 169.593 100.372 1.00 46.69  ? 325 PRO C N   1 
ATOM   11740 C CA  . PRO C 1 325 ? 151.764 170.573 101.448 1.00 45.60  ? 325 PRO C CA  1 
ATOM   11741 C C   . PRO C 1 325 ? 150.522 170.364 102.330 1.00 41.63  ? 325 PRO C C   1 
ATOM   11742 O O   . PRO C 1 325 ? 150.483 170.853 103.456 1.00 45.69  ? 325 PRO C O   1 
ATOM   11743 C CB  . PRO C 1 325 ? 151.691 171.940 100.760 1.00 45.82  ? 325 PRO C CB  1 
ATOM   11744 C CG  . PRO C 1 325 ? 152.406 171.717 99.439  1.00 45.17  ? 325 PRO C CG  1 
ATOM   11745 C CD  . PRO C 1 325 ? 152.024 170.285 99.097  1.00 38.94  ? 325 PRO C CD  1 
ATOM   11746 N N   . LEU C 1 326 ? 149.505 169.632 101.872 1.00 41.86  ? 326 LEU C N   1 
ATOM   11747 C CA  . LEU C 1 326 ? 148.337 169.277 102.684 1.00 36.72  ? 326 LEU C CA  1 
ATOM   11748 C C   . LEU C 1 326 ? 148.618 168.128 103.667 1.00 38.91  ? 326 LEU C C   1 
ATOM   11749 O O   . LEU C 1 326 ? 147.744 167.759 104.441 1.00 46.61  ? 326 LEU C O   1 
ATOM   11750 C CB  . LEU C 1 326 ? 147.144 168.932 101.774 1.00 40.92  ? 326 LEU C CB  1 
ATOM   11751 C CG  . LEU C 1 326 ? 146.618 170.057 100.875 1.00 38.39  ? 326 LEU C CG  1 
ATOM   11752 C CD1 . LEU C 1 326 ? 145.593 169.460 99.913  1.00 38.11  ? 326 LEU C CD1 1 
ATOM   11753 C CD2 . LEU C 1 326 ? 145.953 171.151 101.698 1.00 36.75  ? 326 LEU C CD2 1 
ATOM   11754 N N   . SER C 1 327 ? 149.804 167.527 103.657 1.00 36.25  ? 327 SER C N   1 
ATOM   11755 C CA  . SER C 1 327 ? 150.187 166.466 104.594 1.00 29.97  ? 327 SER C CA  1 
ATOM   11756 C C   . SER C 1 327 ? 150.382 166.991 106.017 1.00 31.75  ? 327 SER C C   1 
ATOM   11757 O O   . SER C 1 327 ? 150.816 168.122 106.218 1.00 32.83  ? 327 SER C O   1 
ATOM   11758 C CB  . SER C 1 327 ? 151.487 165.792 104.156 1.00 32.56  ? 327 SER C CB  1 
ATOM   11759 O OG  . SER C 1 327 ? 151.433 165.413 102.804 1.00 36.29  ? 327 SER C OG  1 
ATOM   11760 N N   . ARG C 1 328 ? 150.121 166.141 107.015 1.00 31.08  ? 328 ARG C N   1 
ATOM   11761 C CA  . ARG C 1 328 ? 150.610 166.287 108.395 1.00 23.68  ? 328 ARG C CA  1 
ATOM   11762 C C   . ARG C 1 328 ? 151.718 165.289 108.741 1.00 28.08  ? 328 ARG C C   1 
ATOM   11763 O O   . ARG C 1 328 ? 152.501 165.558 109.637 1.00 25.13  ? 328 ARG C O   1 
ATOM   11764 C CB  . ARG C 1 328 ? 149.453 166.167 109.397 1.00 25.11  ? 328 ARG C CB  1 
ATOM   11765 C CG  . ARG C 1 328 ? 148.505 167.371 109.358 1.00 19.59  ? 328 ARG C CG  1 
ATOM   11766 C CD  . ARG C 1 328 ? 147.607 167.452 110.598 1.00 29.13  ? 328 ARG C CD  1 
ATOM   11767 N NE  . ARG C 1 328 ? 148.355 167.826 111.812 1.00 24.99  ? 328 ARG C NE  1 
ATOM   11768 C CZ  . ARG C 1 328 ? 148.482 169.033 112.313 1.00 25.27  ? 328 ARG C CZ  1 
ATOM   11769 N NH1 . ARG C 1 328 ? 149.303 169.252 113.285 1.00 24.88  ? 328 ARG C NH1 1 
ATOM   11770 N NH2 . ARG C 1 328 ? 147.830 170.051 111.846 1.00 31.15  ? 328 ARG C NH2 1 
ATOM   11771 N N   . LYS C 1 329 ? 151.810 164.169 108.031 1.00 28.15  ? 329 LYS C N   1 
ATOM   11772 C CA  . LYS C 1 329 ? 152.885 163.182 108.124 1.00 25.81  ? 329 LYS C CA  1 
ATOM   11773 C C   . LYS C 1 329 ? 153.743 163.264 106.866 1.00 24.79  ? 329 LYS C C   1 
ATOM   11774 O O   . LYS C 1 329 ? 153.210 163.289 105.768 1.00 33.60  ? 329 LYS C O   1 
ATOM   11775 C CB  . LYS C 1 329 ? 152.250 161.801 108.306 1.00 22.68  ? 329 LYS C CB  1 
ATOM   11776 C CG  . LYS C 1 329 ? 153.266 160.671 108.478 1.00 18.43  ? 329 LYS C CG  1 
ATOM   11777 C CD  . LYS C 1 329 ? 152.541 159.330 108.527 1.00 23.14  ? 329 LYS C CD  1 
ATOM   11778 C CE  . LYS C 1 329 ? 153.540 158.191 108.713 1.00 24.53  ? 329 LYS C CE  1 
ATOM   11779 N NZ  . LYS C 1 329 ? 152.860 156.881 108.812 1.00 28.35  ? 329 LYS C NZ  1 
ATOM   11780 N N   . PHE C 1 330 ? 155.059 163.280 107.019 1.00 25.43  ? 330 PHE C N   1 
ATOM   11781 C CA  . PHE C 1 330 ? 156.027 163.257 105.928 1.00 20.80  ? 330 PHE C CA  1 
ATOM   11782 C C   . PHE C 1 330 ? 156.986 162.086 106.123 1.00 26.90  ? 330 PHE C C   1 
ATOM   11783 O O   . PHE C 1 330 ? 157.704 162.057 107.117 1.00 34.63  ? 330 PHE C O   1 
ATOM   11784 C CB  . PHE C 1 330 ? 156.791 164.588 105.890 1.00 24.02  ? 330 PHE C CB  1 
ATOM   11785 C CG  . PHE C 1 330 ? 155.905 165.814 105.819 1.00 35.48  ? 330 PHE C CG  1 
ATOM   11786 C CD1 . PHE C 1 330 ? 155.413 166.406 106.998 1.00 36.04  ? 330 PHE C CD1 1 
ATOM   11787 C CD2 . PHE C 1 330 ? 155.535 166.332 104.570 1.00 29.88  ? 330 PHE C CD2 1 
ATOM   11788 C CE1 . PHE C 1 330 ? 154.535 167.494 106.923 1.00 32.97  ? 330 PHE C CE1 1 
ATOM   11789 C CE2 . PHE C 1 330 ? 154.674 167.433 104.493 1.00 29.71  ? 330 PHE C CE2 1 
ATOM   11790 C CZ  . PHE C 1 330 ? 154.165 168.002 105.669 1.00 33.65  ? 330 PHE C CZ  1 
ATOM   11791 N N   . THR C 1 331 ? 157.053 161.130 105.205 1.00 37.38  ? 331 THR C N   1 
ATOM   11792 C CA  . THR C 1 331 ? 158.100 160.099 105.247 1.00 27.60  ? 331 THR C CA  1 
ATOM   11793 C C   . THR C 1 331 ? 159.474 160.728 105.019 1.00 26.87  ? 331 THR C C   1 
ATOM   11794 O O   . THR C 1 331 ? 159.675 161.501 104.088 1.00 35.26  ? 331 THR C O   1 
ATOM   11795 C CB  . THR C 1 331 ? 157.813 158.944 104.284 1.00 30.41  ? 331 THR C CB  1 
ATOM   11796 O OG1 . THR C 1 331 ? 158.720 157.908 104.551 1.00 30.29  ? 331 THR C OG1 1 
ATOM   11797 C CG2 . THR C 1 331 ? 157.957 159.271 102.800 1.00 39.58  ? 331 THR C CG2 1 
ATOM   11798 N N   . GLU C 1 332 ? 160.426 160.447 105.897 1.00 33.92  ? 332 GLU C N   1 
ATOM   11799 C CA  . GLU C 1 332 ? 161.785 160.972 105.824 1.00 32.38  ? 332 GLU C CA  1 
ATOM   11800 C C   . GLU C 1 332 ? 162.724 159.977 105.138 1.00 34.65  ? 332 GLU C C   1 
ATOM   11801 O O   . GLU C 1 332 ? 163.461 160.347 104.227 1.00 41.90  ? 332 GLU C O   1 
ATOM   11802 C CB  . GLU C 1 332 ? 162.253 161.321 107.237 1.00 32.51  ? 332 GLU C CB  1 
ATOM   11803 C CG  . GLU C 1 332 ? 163.576 162.088 107.215 1.00 37.65  ? 332 GLU C CG  1 
ATOM   11804 C CD  . GLU C 1 332 ? 163.931 162.623 108.602 1.00 45.11  ? 332 GLU C CD  1 
ATOM   11805 O OE1 . GLU C 1 332 ? 163.735 161.900 109.595 1.00 41.83  ? 332 GLU C OE1 1 
ATOM   11806 O OE2 . GLU C 1 332 ? 164.443 163.762 108.720 1.00 48.48  ? 332 GLU C OE2 1 
ATOM   11807 N N   . TRP C 1 333 ? 162.648 158.705 105.529 1.00 34.79  ? 333 TRP C N   1 
ATOM   11808 C CA  . TRP C 1 333 ? 163.221 157.570 104.807 1.00 30.29  ? 333 TRP C CA  1 
ATOM   11809 C C   . TRP C 1 333 ? 162.511 156.266 105.174 1.00 30.89  ? 333 TRP C C   1 
ATOM   11810 O O   . TRP C 1 333 ? 161.876 156.148 106.220 1.00 35.80  ? 333 TRP C O   1 
ATOM   11811 C CB  . TRP C 1 333 ? 164.737 157.466 105.033 1.00 26.23  ? 333 TRP C CB  1 
ATOM   11812 C CG  . TRP C 1 333 ? 165.239 157.312 106.435 1.00 28.35  ? 333 TRP C CG  1 
ATOM   11813 C CD1 . TRP C 1 333 ? 165.682 158.326 107.207 1.00 30.22  ? 333 TRP C CD1 1 
ATOM   11814 C CD2 . TRP C 1 333 ? 165.414 156.100 107.232 1.00 33.81  ? 333 TRP C CD2 1 
ATOM   11815 N NE1 . TRP C 1 333 ? 166.137 157.830 108.406 1.00 33.66  ? 333 TRP C NE1 1 
ATOM   11816 C CE2 . TRP C 1 333 ? 166.041 156.461 108.461 1.00 32.15  ? 333 TRP C CE2 1 
ATOM   11817 C CE3 . TRP C 1 333 ? 165.138 154.729 107.044 1.00 33.16  ? 333 TRP C CE3 1 
ATOM   11818 C CZ2 . TRP C 1 333 ? 166.407 155.519 109.428 1.00 27.43  ? 333 TRP C CZ2 1 
ATOM   11819 C CZ3 . TRP C 1 333 ? 165.453 153.781 108.033 1.00 32.88  ? 333 TRP C CZ3 1 
ATOM   11820 C CH2 . TRP C 1 333 ? 166.103 154.171 109.215 1.00 32.98  ? 333 TRP C CH2 1 
ATOM   11821 N N   . CYS C 1 334 ? 162.613 155.271 104.300 1.00 39.47  ? 334 CYS C N   1 
ATOM   11822 C CA  . CYS C 1 334 ? 162.058 153.940 104.494 1.00 33.46  ? 334 CYS C CA  1 
ATOM   11823 C C   . CYS C 1 334 ? 163.080 152.896 104.031 1.00 35.78  ? 334 CYS C C   1 
ATOM   11824 O O   . CYS C 1 334 ? 163.603 152.995 102.925 1.00 44.07  ? 334 CYS C O   1 
ATOM   11825 C CB  . CYS C 1 334 ? 160.732 153.894 103.727 1.00 33.36  ? 334 CYS C CB  1 
ATOM   11826 S SG  . CYS C 1 334 ? 159.889 152.318 103.963 1.00 58.05  ? 334 CYS C SG  1 
ATOM   11827 N N   . TYR C 1 335 ? 163.379 151.897 104.856 1.00 30.38  ? 335 TYR C N   1 
ATOM   11828 C CA  . TYR C 1 335 ? 164.394 150.883 104.572 1.00 30.98  ? 335 TYR C CA  1 
ATOM   11829 C C   . TYR C 1 335 ? 163.988 149.563 105.227 1.00 34.11  ? 335 TYR C C   1 
ATOM   11830 O O   . TYR C 1 335 ? 163.989 149.423 106.449 1.00 36.00  ? 335 TYR C O   1 
ATOM   11831 C CB  . TYR C 1 335 ? 165.773 151.371 105.034 1.00 34.36  ? 335 TYR C CB  1 
ATOM   11832 C CG  . TYR C 1 335 ? 166.930 150.464 104.673 1.00 33.63  ? 335 TYR C CG  1 
ATOM   11833 C CD1 . TYR C 1 335 ? 167.308 149.425 105.537 1.00 34.68  ? 335 TYR C CD1 1 
ATOM   11834 C CD2 . TYR C 1 335 ? 167.652 150.675 103.487 1.00 34.02  ? 335 TYR C CD2 1 
ATOM   11835 C CE1 . TYR C 1 335 ? 168.383 148.576 105.203 1.00 29.85  ? 335 TYR C CE1 1 
ATOM   11836 C CE2 . TYR C 1 335 ? 168.714 149.819 103.138 1.00 35.97  ? 335 TYR C CE2 1 
ATOM   11837 C CZ  . TYR C 1 335 ? 169.080 148.767 103.997 1.00 36.22  ? 335 TYR C CZ  1 
ATOM   11838 O OH  . TYR C 1 335 ? 170.110 147.949 103.668 1.00 36.21  ? 335 TYR C OH  1 
ATOM   11839 N N   . GLY C 1 336 ? 163.583 148.591 104.418 1.00 37.97  ? 336 GLY C N   1 
ATOM   11840 C CA  . GLY C 1 336 ? 163.031 147.338 104.904 1.00 29.88  ? 336 GLY C CA  1 
ATOM   11841 C C   . GLY C 1 336 ? 161.775 147.571 105.753 1.00 31.06  ? 336 GLY C C   1 
ATOM   11842 O O   . GLY C 1 336 ? 160.924 148.376 105.372 1.00 40.15  ? 336 GLY C O   1 
ATOM   11843 N N   . PRO C 1 337 ? 161.640 146.918 106.918 1.00 32.92  ? 337 PRO C N   1 
ATOM   11844 C CA  . PRO C 1 337 ? 160.485 147.063 107.801 1.00 32.92  ? 337 PRO C CA  1 
ATOM   11845 C C   . PRO C 1 337 ? 160.436 148.401 108.552 1.00 35.80  ? 337 PRO C C   1 
ATOM   11846 O O   . PRO C 1 337 ? 159.496 148.627 109.305 1.00 36.84  ? 337 PRO C O   1 
ATOM   11847 C CB  . PRO C 1 337 ? 160.585 145.875 108.753 1.00 29.27  ? 337 PRO C CB  1 
ATOM   11848 C CG  . PRO C 1 337 ? 162.090 145.655 108.869 1.00 31.07  ? 337 PRO C CG  1 
ATOM   11849 C CD  . PRO C 1 337 ? 162.591 145.981 107.476 1.00 30.80  ? 337 PRO C CD  1 
ATOM   11850 N N   . VAL C 1 338 ? 161.427 149.280 108.380 1.00 36.91  ? 338 VAL C N   1 
ATOM   11851 C CA  . VAL C 1 338 ? 161.561 150.544 109.108 1.00 32.08  ? 338 VAL C CA  1 
ATOM   11852 C C   . VAL C 1 338 ? 161.089 151.723 108.257 1.00 34.98  ? 338 VAL C C   1 
ATOM   11853 O O   . VAL C 1 338 ? 161.595 151.949 107.161 1.00 35.76  ? 338 VAL C O   1 
ATOM   11854 C CB  . VAL C 1 338 ? 163.016 150.771 109.560 1.00 36.95  ? 338 VAL C CB  1 
ATOM   11855 C CG1 . VAL C 1 338 ? 163.122 151.989 110.485 1.00 32.48  ? 338 VAL C CG1 1 
ATOM   11856 C CG2 . VAL C 1 338 ? 163.580 149.545 110.289 1.00 33.46  ? 338 VAL C CG2 1 
ATOM   11857 N N   . ARG C 1 339 ? 160.151 152.507 108.791 1.00 35.48  ? 339 ARG C N   1 
ATOM   11858 C CA  . ARG C 1 339 ? 159.714 153.812 108.272 1.00 27.93  ? 339 ARG C CA  1 
ATOM   11859 C C   . ARG C 1 339 ? 160.059 154.890 109.281 1.00 27.60  ? 339 ARG C C   1 
ATOM   11860 O O   . ARG C 1 339 ? 159.606 154.830 110.416 1.00 33.31  ? 339 ARG C O   1 
ATOM   11861 C CB  . ARG C 1 339 ? 158.202 153.796 108.013 1.00 34.42  ? 339 ARG C CB  1 
ATOM   11862 C CG  . ARG C 1 339 ? 157.850 153.024 106.746 1.00 37.98  ? 339 ARG C CG  1 
ATOM   11863 C CD  . ARG C 1 339 ? 156.339 152.975 106.521 1.00 36.89  ? 339 ARG C CD  1 
ATOM   11864 N NE  . ARG C 1 339 ? 156.013 152.333 105.234 1.00 40.28  ? 339 ARG C NE  1 
ATOM   11865 C CZ  . ARG C 1 339 ? 155.918 152.912 104.056 1.00 46.29  ? 339 ARG C CZ  1 
ATOM   11866 N NH1 . ARG C 1 339 ? 155.647 152.206 102.998 1.00 44.76  ? 339 ARG C NH1 1 
ATOM   11867 N NH2 . ARG C 1 339 ? 156.071 154.196 103.891 1.00 44.45  ? 339 ARG C NH2 1 
ATOM   11868 N N   . VAL C 1 340 ? 160.798 155.910 108.877 1.00 27.34  ? 340 VAL C N   1 
ATOM   11869 C CA  . VAL C 1 340 ? 161.011 157.109 109.688 1.00 26.58  ? 340 VAL C CA  1 
ATOM   11870 C C   . VAL C 1 340 ? 160.189 158.243 109.104 1.00 28.65  ? 340 VAL C C   1 
ATOM   11871 O O   . VAL C 1 340 ? 160.307 158.552 107.926 1.00 28.79  ? 340 VAL C O   1 
ATOM   11872 C CB  . VAL C 1 340 ? 162.500 157.451 109.804 1.00 25.84  ? 340 VAL C CB  1 
ATOM   11873 C CG1 . VAL C 1 340 ? 162.709 158.699 110.661 1.00 24.74  ? 340 VAL C CG1 1 
ATOM   11874 C CG2 . VAL C 1 340 ? 163.233 156.280 110.454 1.00 24.82  ? 340 VAL C CG2 1 
ATOM   11875 N N   . SER C 1 341 ? 159.328 158.846 109.915 1.00 32.48  ? 341 SER C N   1 
ATOM   11876 C CA  . SER C 1 341 ? 158.421 159.916 109.501 1.00 25.77  ? 341 SER C CA  1 
ATOM   11877 C C   . SER C 1 341 ? 158.551 161.132 110.395 1.00 24.67  ? 341 SER C C   1 
ATOM   11878 O O   . SER C 1 341 ? 158.759 161.006 111.593 1.00 27.60  ? 341 SER C O   1 
ATOM   11879 C CB  . SER C 1 341 ? 156.968 159.453 109.524 1.00 30.97  ? 341 SER C CB  1 
ATOM   11880 O OG  . SER C 1 341 ? 156.772 158.353 108.666 1.00 35.52  ? 341 SER C OG  1 
ATOM   11881 N N   . LEU C 1 342 ? 158.343 162.309 109.827 1.00 25.72  ? 342 LEU C N   1 
ATOM   11882 C CA  . LEU C 1 342 ? 158.101 163.547 110.554 1.00 25.86  ? 342 LEU C CA  1 
ATOM   11883 C C   . LEU C 1 342 ? 156.594 163.790 110.641 1.00 22.68  ? 342 LEU C C   1 
ATOM   11884 O O   . LEU C 1 342 ? 155.911 163.783 109.625 1.00 25.10  ? 342 LEU C O   1 
ATOM   11885 C CB  . LEU C 1 342 ? 158.780 164.706 109.814 1.00 29.61  ? 342 LEU C CB  1 
ATOM   11886 C CG  . LEU C 1 342 ? 160.312 164.651 109.770 1.00 27.78  ? 342 LEU C CG  1 
ATOM   11887 C CD1 . LEU C 1 342 ? 160.832 165.805 108.915 1.00 28.52  ? 342 LEU C CD1 1 
ATOM   11888 C CD2 . LEU C 1 342 ? 160.924 164.757 111.161 1.00 24.13  ? 342 LEU C CD2 1 
ATOM   11889 N N   . TYR C 1 343 ? 156.071 164.028 111.835 1.00 30.00  ? 343 TYR C N   1 
ATOM   11890 C CA  . TYR C 1 343 ? 154.689 164.449 112.058 1.00 20.08  ? 343 TYR C CA  1 
ATOM   11891 C C   . TYR C 1 343 ? 154.617 165.909 112.490 1.00 22.39  ? 343 TYR C C   1 
ATOM   11892 O O   . TYR C 1 343 ? 155.304 166.318 113.417 1.00 27.10  ? 343 TYR C O   1 
ATOM   11893 C CB  . TYR C 1 343 ? 154.033 163.587 113.127 1.00 15.35  ? 343 TYR C CB  1 
ATOM   11894 C CG  . TYR C 1 343 ? 153.732 162.164 112.726 1.00 17.42  ? 343 TYR C CG  1 
ATOM   11895 C CD1 . TYR C 1 343 ? 154.687 161.150 112.901 1.00 16.41  ? 343 TYR C CD1 1 
ATOM   11896 C CD2 . TYR C 1 343 ? 152.453 161.852 112.240 1.00 14.89  ? 343 TYR C CD2 1 
ATOM   11897 C CE1 . TYR C 1 343 ? 154.345 159.812 112.628 1.00 12.58  ? 343 TYR C CE1 1 
ATOM   11898 C CE2 . TYR C 1 343 ? 152.112 160.521 111.981 1.00 14.83  ? 343 TYR C CE2 1 
ATOM   11899 C CZ  . TYR C 1 343 ? 153.048 159.495 112.191 1.00 21.08  ? 343 TYR C CZ  1 
ATOM   11900 O OH  . TYR C 1 343 ? 152.689 158.210 111.952 1.00 32.08  ? 343 TYR C OH  1 
ATOM   11901 N N   . ASP C 1 344 ? 153.749 166.679 111.858 1.00 25.80  ? 344 ASP C N   1 
ATOM   11902 C CA  . ASP C 1 344 ? 153.431 168.065 112.185 1.00 27.02  ? 344 ASP C CA  1 
ATOM   11903 C C   . ASP C 1 344 ? 152.729 168.179 113.554 1.00 27.95  ? 344 ASP C C   1 
ATOM   11904 O O   . ASP C 1 344 ? 151.623 167.668 113.744 1.00 35.52  ? 344 ASP C O   1 
ATOM   11905 C CB  . ASP C 1 344 ? 152.567 168.579 111.026 1.00 22.53  ? 344 ASP C CB  1 
ATOM   11906 C CG  . ASP C 1 344 ? 152.097 170.026 111.125 1.00 30.51  ? 344 ASP C CG  1 
ATOM   11907 O OD1 . ASP C 1 344 ? 152.273 170.675 112.175 1.00 38.11  ? 344 ASP C OD1 1 
ATOM   11908 O OD2 . ASP C 1 344 ? 151.516 170.506 110.130 1.00 31.30  ? 344 ASP C OD2 1 
ATOM   11909 N N   . LEU C 1 345 ? 153.360 168.864 114.508 1.00 20.36  ? 345 LEU C N   1 
ATOM   11910 C CA  . LEU C 1 345 ? 152.846 169.068 115.865 1.00 21.61  ? 345 LEU C CA  1 
ATOM   11911 C C   . LEU C 1 345 ? 152.086 170.382 116.084 1.00 24.73  ? 345 LEU C C   1 
ATOM   11912 O O   . LEU C 1 345 ? 151.718 170.678 117.218 1.00 36.33  ? 345 LEU C O   1 
ATOM   11913 C CB  . LEU C 1 345 ? 154.004 168.963 116.871 1.00 28.45  ? 345 LEU C CB  1 
ATOM   11914 C CG  . LEU C 1 345 ? 154.651 167.585 117.039 1.00 25.07  ? 345 LEU C CG  1 
ATOM   11915 C CD1 . LEU C 1 345 ? 155.473 167.643 118.326 1.00 24.04  ? 345 LEU C CD1 1 
ATOM   11916 C CD2 . LEU C 1 345 ? 153.638 166.451 117.170 1.00 30.03  ? 345 LEU C CD2 1 
ATOM   11917 N N   . SER C 1 346 ? 151.841 171.183 115.048 1.00 30.17  ? 346 SER C N   1 
ATOM   11918 C CA  . SER C 1 346 ? 151.412 172.596 115.135 1.00 36.47  ? 346 SER C CA  1 
ATOM   11919 C C   . SER C 1 346 ? 150.311 172.921 116.160 1.00 43.13  ? 346 SER C C   1 
ATOM   11920 O O   . SER C 1 346 ? 150.488 173.816 116.988 1.00 46.70  ? 346 SER C O   1 
ATOM   11921 C CB  . SER C 1 346 ? 150.997 173.099 113.749 1.00 28.64  ? 346 SER C CB  1 
ATOM   11922 O OG  . SER C 1 346 ? 150.264 172.114 113.053 1.00 36.15  ? 346 SER C OG  1 
ATOM   11923 N N   . SER C 1 347 ? 149.198 172.189 116.144 1.00 28.09  ? 347 SER C N   1 
ATOM   11924 C CA  . SER C 1 347 ? 148.092 172.339 117.107 1.00 24.99  ? 347 SER C CA  1 
ATOM   11925 C C   . SER C 1 347 ? 147.981 171.181 118.112 1.00 28.30  ? 347 SER C C   1 
ATOM   11926 O O   . SER C 1 347 ? 146.983 171.038 118.817 1.00 27.09  ? 347 SER C O   1 
ATOM   11927 C CB  . SER C 1 347 ? 146.796 172.562 116.329 1.00 27.98  ? 347 SER C CB  1 
ATOM   11928 O OG  . SER C 1 347 ? 146.588 171.518 115.401 1.00 38.89  ? 347 SER C OG  1 
ATOM   11929 N N   . VAL C 1 348 ? 149.011 170.337 118.185 1.00 32.11  ? 348 VAL C N   1 
ATOM   11930 C CA  . VAL C 1 348 ? 149.051 169.100 118.967 1.00 26.66  ? 348 VAL C CA  1 
ATOM   11931 C C   . VAL C 1 348 ? 149.819 169.261 120.274 1.00 28.55  ? 348 VAL C C   1 
ATOM   11932 O O   . VAL C 1 348 ? 149.309 168.888 121.326 1.00 27.33  ? 348 VAL C O   1 
ATOM   11933 C CB  . VAL C 1 348 ? 149.590 167.932 118.123 1.00 29.12  ? 348 VAL C CB  1 
ATOM   11934 C CG1 . VAL C 1 348 ? 149.710 166.640 118.929 1.00 28.49  ? 348 VAL C CG1 1 
ATOM   11935 C CG2 . VAL C 1 348 ? 148.681 167.644 116.928 1.00 18.74  ? 348 VAL C CG2 1 
ATOM   11936 N N   . ASP C 1 349 ? 151.027 169.817 120.221 1.00 34.25  ? 349 ASP C N   1 
ATOM   11937 C CA  . ASP C 1 349 ? 151.905 169.947 121.385 1.00 35.97  ? 349 ASP C CA  1 
ATOM   11938 C C   . ASP C 1 349 ? 151.292 170.862 122.462 1.00 36.18  ? 349 ASP C C   1 
ATOM   11939 O O   . ASP C 1 349 ? 150.753 171.928 122.168 1.00 44.84  ? 349 ASP C O   1 
ATOM   11940 C CB  . ASP C 1 349 ? 153.284 170.432 120.920 1.00 34.90  ? 349 ASP C CB  1 
ATOM   11941 C CG  . ASP C 1 349 ? 154.355 170.463 122.019 1.00 44.47  ? 349 ASP C CG  1 
ATOM   11942 O OD1 . ASP C 1 349 ? 154.171 169.810 123.074 1.00 41.19  ? 349 ASP C OD1 1 
ATOM   11943 O OD2 . ASP C 1 349 ? 155.369 171.155 121.801 1.00 49.03  ? 349 ASP C OD2 1 
ATOM   11944 N N   . SER C 1 350 ? 151.391 170.453 123.723 1.00 33.59  ? 350 SER C N   1 
ATOM   11945 C CA  . SER C 1 350 ? 150.863 171.129 124.914 1.00 32.69  ? 350 SER C CA  1 
ATOM   11946 C C   . SER C 1 350 ? 151.597 172.419 125.306 1.00 36.35  ? 350 SER C C   1 
ATOM   11947 O O   . SER C 1 350 ? 151.189 173.096 126.250 1.00 39.80  ? 350 SER C O   1 
ATOM   11948 C CB  . SER C 1 350 ? 150.894 170.133 126.069 1.00 34.43  ? 350 SER C CB  1 
ATOM   11949 O OG  . SER C 1 350 ? 152.185 169.583 126.191 1.00 41.87  ? 350 SER C OG  1 
ATOM   11950 N N   . TRP C 1 351 ? 152.657 172.795 124.587 1.00 39.40  ? 351 TRP C N   1 
ATOM   11951 C CA  . TRP C 1 351 ? 153.277 174.118 124.671 1.00 39.52  ? 351 TRP C CA  1 
ATOM   11952 C C   . TRP C 1 351 ? 152.298 175.239 124.306 1.00 43.73  ? 351 TRP C C   1 
ATOM   11953 O O   . TRP C 1 351 ? 152.321 176.304 124.914 1.00 44.59  ? 351 TRP C O   1 
ATOM   11954 C CB  . TRP C 1 351 ? 154.497 174.134 123.747 1.00 41.65  ? 351 TRP C CB  1 
ATOM   11955 C CG  . TRP C 1 351 ? 155.158 175.461 123.559 1.00 46.52  ? 351 TRP C CG  1 
ATOM   11956 C CD1 . TRP C 1 351 ? 156.120 175.985 124.347 1.00 42.19  ? 351 TRP C CD1 1 
ATOM   11957 C CD2 . TRP C 1 351 ? 154.894 176.471 122.536 1.00 44.75  ? 351 TRP C CD2 1 
ATOM   11958 N NE1 . TRP C 1 351 ? 156.486 177.230 123.880 1.00 42.79  ? 351 TRP C NE1 1 
ATOM   11959 C CE2 . TRP C 1 351 ? 155.757 177.584 122.766 1.00 43.02  ? 351 TRP C CE2 1 
ATOM   11960 C CE3 . TRP C 1 351 ? 154.035 176.541 121.421 1.00 38.80  ? 351 TRP C CE3 1 
ATOM   11961 C CZ2 . TRP C 1 351 ? 155.749 178.719 121.947 1.00 42.38  ? 351 TRP C CZ2 1 
ATOM   11962 C CZ3 . TRP C 1 351 ? 154.009 177.681 120.601 1.00 43.16  ? 351 TRP C CZ3 1 
ATOM   11963 C CH2 . TRP C 1 351 ? 154.858 178.769 120.863 1.00 46.16  ? 351 TRP C CH2 1 
ATOM   11964 N N   . GLU C 1 352 ? 151.418 174.996 123.335 1.00 46.79  ? 352 GLU C N   1 
ATOM   11965 C CA  . GLU C 1 352 ? 150.371 175.928 122.918 1.00 41.40  ? 352 GLU C CA  1 
ATOM   11966 C C   . GLU C 1 352 ? 149.091 175.753 123.751 1.00 43.03  ? 352 GLU C C   1 
ATOM   11967 O O   . GLU C 1 352 ? 148.724 174.649 124.154 1.00 42.01  ? 352 GLU C O   1 
ATOM   11968 C CB  . GLU C 1 352 ? 150.130 175.737 121.409 1.00 45.07  ? 352 GLU C CB  1 
ATOM   11969 C CG  . GLU C 1 352 ? 149.098 176.648 120.741 1.00 46.36  ? 352 GLU C CG  1 
ATOM   11970 C CD  . GLU C 1 352 ? 149.396 178.148 120.891 1.00 53.21  ? 352 GLU C CD  1 
ATOM   11971 O OE1 . GLU C 1 352 ? 149.392 178.657 122.035 1.00 51.00  ? 352 GLU C OE1 1 
ATOM   11972 O OE2 . GLU C 1 352 ? 149.600 178.820 119.860 1.00 52.49  ? 352 GLU C OE2 1 
ATOM   11973 N N   . LYS C 1 353 ? 148.373 176.847 124.000 1.00 45.08  ? 353 LYS C N   1 
ATOM   11974 C CA  . LYS C 1 353 ? 147.085 176.833 124.704 1.00 46.63  ? 353 LYS C CA  1 
ATOM   11975 C C   . LYS C 1 353 ? 146.037 176.039 123.912 1.00 47.55  ? 353 LYS C C   1 
ATOM   11976 O O   . LYS C 1 353 ? 145.945 176.181 122.694 1.00 43.78  ? 353 LYS C O   1 
ATOM   11977 C CB  . LYS C 1 353 ? 146.641 178.287 124.934 1.00 46.56  ? 353 LYS C CB  1 
ATOM   11978 C CG  . LYS C 1 353 ? 145.376 178.407 125.786 1.00 49.58  ? 353 LYS C CG  1 
ATOM   11979 C CD  . LYS C 1 353 ? 144.930 179.856 125.933 1.00 49.77  ? 353 LYS C CD  1 
ATOM   11980 C CE  . LYS C 1 353 ? 143.612 179.949 126.685 1.00 51.18  ? 353 LYS C CE  1 
ATOM   11981 N NZ  . LYS C 1 353 ? 143.107 181.325 126.770 1.00 49.38  ? 353 LYS C NZ  1 
ATOM   11982 N N   . ASN C 1 354 ? 145.193 175.266 124.601 1.00 40.45  ? 354 ASN C N   1 
ATOM   11983 C CA  . ASN C 1 354 ? 144.045 174.567 124.010 1.00 34.00  ? 354 ASN C CA  1 
ATOM   11984 C C   . ASN C 1 354 ? 144.454 173.607 122.872 1.00 33.99  ? 354 ASN C C   1 
ATOM   11985 O O   . ASN C 1 354 ? 143.851 173.590 121.803 1.00 45.33  ? 354 ASN C O   1 
ATOM   11986 C CB  . ASN C 1 354 ? 142.972 175.612 123.632 1.00 39.77  ? 354 ASN C CB  1 
ATOM   11987 C CG  . ASN C 1 354 ? 141.628 175.010 123.262 1.00 46.37  ? 354 ASN C CG  1 
ATOM   11988 O OD1 . ASN C 1 354 ? 141.089 174.181 123.969 1.00 45.96  ? 354 ASN C OD1 1 
ATOM   11989 N ND2 . ASN C 1 354 ? 141.023 175.431 122.180 1.00 43.65  ? 354 ASN C ND2 1 
ATOM   11990 N N   . SER C 1 355 ? 145.542 172.861 123.057 1.00 29.65  ? 355 SER C N   1 
ATOM   11991 C CA  . SER C 1 355 ? 146.050 171.906 122.072 1.00 21.78  ? 355 SER C CA  1 
ATOM   11992 C C   . SER C 1 355 ? 145.228 170.619 122.045 1.00 19.27  ? 355 SER C C   1 
ATOM   11993 O O   . SER C 1 355 ? 144.426 170.356 122.937 1.00 28.48  ? 355 SER C O   1 
ATOM   11994 C CB  . SER C 1 355 ? 147.525 171.615 122.331 1.00 20.95  ? 355 SER C CB  1 
ATOM   11995 O OG  . SER C 1 355 ? 147.711 170.655 123.345 1.00 27.57  ? 355 SER C OG  1 
ATOM   11996 N N   . VAL C 1 356 ? 145.444 169.770 121.043 1.00 21.92  ? 356 VAL C N   1 
ATOM   11997 C CA  . VAL C 1 356 ? 144.800 168.446 120.961 1.00 18.73  ? 356 VAL C CA  1 
ATOM   11998 C C   . VAL C 1 356 ? 145.040 167.593 122.206 1.00 15.30  ? 356 VAL C C   1 
ATOM   11999 O O   . VAL C 1 356 ? 144.125 166.909 122.650 1.00 30.37  ? 356 VAL C O   1 
ATOM   12000 C CB  . VAL C 1 356 ? 145.258 167.735 119.681 1.00 25.48  ? 356 VAL C CB  1 
ATOM   12001 C CG1 . VAL C 1 356 ? 145.099 166.223 119.656 1.00 25.95  ? 356 VAL C CG1 1 
ATOM   12002 C CG2 . VAL C 1 356 ? 144.523 168.319 118.476 1.00 19.97  ? 356 VAL C CG2 1 
ATOM   12003 N N   . LEU C 1 357 ? 146.228 167.648 122.810 1.00 35.64  ? 357 LEU C N   1 
ATOM   12004 C CA  . LEU C 1 357 ? 146.516 166.920 124.046 1.00 19.10  ? 357 LEU C CA  1 
ATOM   12005 C C   . LEU C 1 357 ? 145.690 167.422 125.232 1.00 17.29  ? 357 LEU C C   1 
ATOM   12006 O O   . LEU C 1 357 ? 145.091 166.620 125.939 1.00 25.97  ? 357 LEU C O   1 
ATOM   12007 C CB  . LEU C 1 357 ? 148.012 167.023 124.359 1.00 22.65  ? 357 LEU C CB  1 
ATOM   12008 C CG  . LEU C 1 357 ? 148.939 166.239 123.421 1.00 23.00  ? 357 LEU C CG  1 
ATOM   12009 C CD1 . LEU C 1 357 ? 150.379 166.500 123.844 1.00 22.52  ? 357 LEU C CD1 1 
ATOM   12010 C CD2 . LEU C 1 357 ? 148.685 164.737 123.485 1.00 25.16  ? 357 LEU C CD2 1 
ATOM   12011 N N   . GLU C 1 358 ? 145.604 168.738 125.435 1.00 25.47  ? 358 GLU C N   1 
ATOM   12012 C CA  . GLU C 1 358 ? 144.754 169.331 126.469 1.00 20.32  ? 358 GLU C CA  1 
ATOM   12013 C C   . GLU C 1 358 ? 143.267 169.022 126.241 1.00 29.36  ? 358 GLU C C   1 
ATOM   12014 O O   . GLU C 1 358 ? 142.548 168.701 127.186 1.00 36.00  ? 358 GLU C O   1 
ATOM   12015 C CB  . GLU C 1 358 ? 145.034 170.841 126.554 1.00 26.23  ? 358 GLU C CB  1 
ATOM   12016 C CG  . GLU C 1 358 ? 144.147 171.523 127.602 1.00 35.82  ? 358 GLU C CG  1 
ATOM   12017 C CD  . GLU C 1 358 ? 144.696 172.856 128.126 1.00 45.71  ? 358 GLU C CD  1 
ATOM   12018 O OE1 . GLU C 1 358 ? 145.054 173.734 127.309 1.00 46.33  ? 358 GLU C OE1 1 
ATOM   12019 O OE2 . GLU C 1 358 ? 144.737 173.026 129.367 1.00 41.00  ? 358 GLU C OE2 1 
ATOM   12020 N N   . ILE C 1 359 ? 142.806 169.035 124.991 1.00 25.01  ? 359 ILE C N   1 
ATOM   12021 C CA  . ILE C 1 359 ? 141.435 168.681 124.628 1.00 24.21  ? 359 ILE C CA  1 
ATOM   12022 C C   . ILE C 1 359 ? 141.131 167.211 124.911 1.00 23.34  ? 359 ILE C C   1 
ATOM   12023 O O   . ILE C 1 359 ? 140.121 166.930 125.544 1.00 35.36  ? 359 ILE C O   1 
ATOM   12024 C CB  . ILE C 1 359 ? 141.136 169.067 123.168 1.00 23.54  ? 359 ILE C CB  1 
ATOM   12025 C CG1 . ILE C 1 359 ? 141.065 170.601 123.052 1.00 18.08  ? 359 ILE C CG1 1 
ATOM   12026 C CG2 . ILE C 1 359 ? 139.828 168.445 122.662 1.00 22.39  ? 359 ILE C CG2 1 
ATOM   12027 C CD1 . ILE C 1 359 ? 141.196 171.100 121.625 1.00 22.31  ? 359 ILE C CD1 1 
ATOM   12028 N N   . ILE C 1 360 ? 141.962 166.250 124.499 1.00 26.23  ? 360 ILE C N   1 
ATOM   12029 C CA  . ILE C 1 360 ? 141.709 164.827 124.782 1.00 23.61  ? 360 ILE C CA  1 
ATOM   12030 C C   . ILE C 1 360 ? 141.693 164.555 126.290 1.00 26.51  ? 360 ILE C C   1 
ATOM   12031 O O   . ILE C 1 360 ? 140.814 163.850 126.784 1.00 34.65  ? 360 ILE C O   1 
ATOM   12032 C CB  . ILE C 1 360 ? 142.728 163.914 124.068 1.00 28.36  ? 360 ILE C CB  1 
ATOM   12033 C CG1 . ILE C 1 360 ? 142.565 163.995 122.542 1.00 21.88  ? 360 ILE C CG1 1 
ATOM   12034 C CG2 . ILE C 1 360 ? 142.562 162.449 124.512 1.00 21.69  ? 360 ILE C CG2 1 
ATOM   12035 C CD1 . ILE C 1 360 ? 143.782 163.480 121.772 1.00 22.19  ? 360 ILE C CD1 1 
ATOM   12036 N N   . ALA C 1 361 ? 142.635 165.130 127.037 1.00 27.43  ? 361 ALA C N   1 
ATOM   12037 C CA  . ALA C 1 361 ? 142.737 164.913 128.469 1.00 15.71  ? 361 ALA C CA  1 
ATOM   12038 C C   . ALA C 1 361 ? 141.557 165.517 129.252 1.00 23.10  ? 361 ALA C C   1 
ATOM   12039 O O   . ALA C 1 361 ? 140.988 164.821 130.089 1.00 29.44  ? 361 ALA C O   1 
ATOM   12040 C CB  . ALA C 1 361 ? 144.085 165.452 128.932 1.00 19.33  ? 361 ALA C CB  1 
ATOM   12041 N N   . PHE C 1 362 ? 141.167 166.767 128.978 1.00 26.02  ? 362 PHE C N   1 
ATOM   12042 C CA  . PHE C 1 362 ? 140.285 167.532 129.866 1.00 15.26  ? 362 PHE C CA  1 
ATOM   12043 C C   . PHE C 1 362 ? 138.973 168.038 129.263 1.00 25.99  ? 362 PHE C C   1 
ATOM   12044 O O   . PHE C 1 362 ? 138.061 168.336 130.030 1.00 39.19  ? 362 PHE C O   1 
ATOM   12045 C CB  . PHE C 1 362 ? 141.074 168.709 130.453 1.00 20.23  ? 362 PHE C CB  1 
ATOM   12046 C CG  . PHE C 1 362 ? 142.349 168.305 131.158 1.00 25.61  ? 362 PHE C CG  1 
ATOM   12047 C CD1 . PHE C 1 362 ? 142.295 167.599 132.371 1.00 24.75  ? 362 PHE C CD1 1 
ATOM   12048 C CD2 . PHE C 1 362 ? 143.594 168.583 130.572 1.00 29.32  ? 362 PHE C CD2 1 
ATOM   12049 C CE1 . PHE C 1 362 ? 143.480 167.176 132.991 1.00 25.99  ? 362 PHE C CE1 1 
ATOM   12050 C CE2 . PHE C 1 362 ? 144.779 168.160 131.191 1.00 23.42  ? 362 PHE C CE2 1 
ATOM   12051 C CZ  . PHE C 1 362 ? 144.722 167.449 132.398 1.00 27.02  ? 362 PHE C CZ  1 
ATOM   12052 N N   . HIS C 1 363 ? 138.840 168.186 127.941 1.00 26.53  ? 363 HIS C N   1 
ATOM   12053 C CA  . HIS C 1 363 ? 137.635 168.765 127.320 1.00 26.29  ? 363 HIS C CA  1 
ATOM   12054 C C   . HIS C 1 363 ? 136.770 167.718 126.618 1.00 30.54  ? 363 HIS C C   1 
ATOM   12055 O O   . HIS C 1 363 ? 135.566 167.892 126.483 1.00 38.18  ? 363 HIS C O   1 
ATOM   12056 C CB  . HIS C 1 363 ? 138.016 169.863 126.329 1.00 22.45  ? 363 HIS C CB  1 
ATOM   12057 C CG  . HIS C 1 363 ? 138.884 170.977 126.851 1.00 25.72  ? 363 HIS C CG  1 
ATOM   12058 N ND1 . HIS C 1 363 ? 139.471 171.945 126.040 1.00 40.84  ? 363 HIS C ND1 1 
ATOM   12059 C CD2 . HIS C 1 363 ? 139.202 171.257 128.145 1.00 30.29  ? 363 HIS C CD2 1 
ATOM   12060 C CE1 . HIS C 1 363 ? 140.152 172.759 126.857 1.00 36.77  ? 363 HIS C CE1 1 
ATOM   12061 N NE2 . HIS C 1 363 ? 140.006 172.367 128.126 1.00 36.73  ? 363 HIS C NE2 1 
ATOM   12062 N N   . CYS C 1 364 ? 137.372 166.631 126.162 1.00 29.79  ? 364 CYS C N   1 
ATOM   12063 C CA  . CYS C 1 364 ? 136.675 165.493 125.595 1.00 26.62  ? 364 CYS C CA  1 
ATOM   12064 C C   . CYS C 1 364 ? 135.962 164.696 126.703 1.00 34.81  ? 364 CYS C C   1 
ATOM   12065 O O   . CYS C 1 364 ? 136.514 164.501 127.783 1.00 32.33  ? 364 CYS C O   1 
ATOM   12066 C CB  . CYS C 1 364 ? 137.699 164.662 124.817 1.00 24.75  ? 364 CYS C CB  1 
ATOM   12067 S SG  . CYS C 1 364 ? 136.878 163.314 123.951 1.00 25.19  ? 364 CYS C SG  1 
ATOM   12068 N N   . LYS C 1 365 ? 134.758 164.192 126.422 1.00 41.48  ? 365 LYS C N   1 
ATOM   12069 C CA  . LYS C 1 365 ? 133.987 163.299 127.307 1.00 35.42  ? 365 LYS C CA  1 
ATOM   12070 C C   . LYS C 1 365 ? 133.540 161.992 126.651 1.00 34.83  ? 365 LYS C C   1 
ATOM   12071 O O   . LYS C 1 365 ? 132.671 161.294 127.163 1.00 44.31  ? 365 LYS C O   1 
ATOM   12072 C CB  . LYS C 1 365 ? 132.868 164.083 128.006 1.00 41.38  ? 365 LYS C CB  1 
ATOM   12073 C CG  . LYS C 1 365 ? 131.792 164.635 127.069 1.00 41.92  ? 365 LYS C CG  1 
ATOM   12074 C CD  . LYS C 1 365 ? 130.751 165.421 127.869 1.00 42.97  ? 365 LYS C CD  1 
ATOM   12075 C CE  . LYS C 1 365 ? 129.650 165.951 126.953 1.00 44.51  ? 365 LYS C CE  1 
ATOM   12076 N NZ  . LYS C 1 365 ? 128.615 166.680 127.719 1.00 43.68  ? 365 LYS C NZ  1 
ATOM   12077 N N   . SER C 1 366 ? 134.145 161.652 125.520 1.00 34.77  ? 366 SER C N   1 
ATOM   12078 C CA  . SER C 1 366 ? 133.930 160.394 124.804 1.00 33.52  ? 366 SER C CA  1 
ATOM   12079 C C   . SER C 1 366 ? 134.593 159.206 125.520 1.00 28.32  ? 366 SER C C   1 
ATOM   12080 O O   . SER C 1 366 ? 135.676 159.374 126.081 1.00 35.10  ? 366 SER C O   1 
ATOM   12081 C CB  . SER C 1 366 ? 134.491 160.551 123.390 1.00 32.52  ? 366 SER C CB  1 
ATOM   12082 O OG  . SER C 1 366 ? 134.292 159.388 122.626 1.00 33.45  ? 366 SER C OG  1 
ATOM   12083 N N   . PRO C 1 367 ? 134.040 157.981 125.474 1.00 37.32  ? 367 PRO C N   1 
ATOM   12084 C CA  . PRO C 1 367 ? 134.671 156.800 126.072 1.00 37.80  ? 367 PRO C CA  1 
ATOM   12085 C C   . PRO C 1 367 ? 135.966 156.346 125.379 1.00 40.74  ? 367 PRO C C   1 
ATOM   12086 O O   . PRO C 1 367 ? 136.709 155.542 125.932 1.00 48.45  ? 367 PRO C O   1 
ATOM   12087 C CB  . PRO C 1 367 ? 133.599 155.712 126.020 1.00 41.59  ? 367 PRO C CB  1 
ATOM   12088 C CG  . PRO C 1 367 ? 132.723 156.117 124.842 1.00 38.19  ? 367 PRO C CG  1 
ATOM   12089 C CD  . PRO C 1 367 ? 132.735 157.637 124.930 1.00 39.45  ? 367 PRO C CD  1 
ATOM   12090 N N   . ASN C 1 368 ? 136.241 156.829 124.164 1.00 34.15  ? 368 ASN C N   1 
ATOM   12091 C CA  . ASN C 1 368 ? 137.406 156.444 123.360 1.00 34.84  ? 368 ASN C CA  1 
ATOM   12092 C C   . ASN C 1 368 ? 138.616 157.389 123.487 1.00 36.18  ? 368 ASN C C   1 
ATOM   12093 O O   . ASN C 1 368 ? 139.559 157.279 122.704 1.00 44.69  ? 368 ASN C O   1 
ATOM   12094 C CB  . ASN C 1 368 ? 136.970 156.183 121.903 1.00 39.74  ? 368 ASN C CB  1 
ATOM   12095 C CG  . ASN C 1 368 ? 136.470 157.402 121.163 1.00 38.85  ? 368 ASN C CG  1 
ATOM   12096 O OD1 . ASN C 1 368 ? 136.583 158.534 121.605 1.00 46.06  ? 368 ASN C OD1 1 
ATOM   12097 N ND2 . ASN C 1 368 ? 135.855 157.219 120.028 1.00 33.67  ? 368 ASN C ND2 1 
ATOM   12098 N N   . ARG C 1 369 ? 138.659 158.272 124.494 1.00 27.25  ? 369 ARG C N   1 
ATOM   12099 C CA  . ARG C 1 369 ? 139.829 159.120 124.807 1.00 29.07  ? 369 ARG C CA  1 
ATOM   12100 C C   . ARG C 1 369 ? 141.121 158.325 124.931 1.00 28.00  ? 369 ARG C C   1 
ATOM   12101 O O   . ARG C 1 369 ? 142.164 158.743 124.441 1.00 29.83  ? 369 ARG C O   1 
ATOM   12102 C CB  . ARG C 1 369 ? 139.581 159.882 126.117 1.00 28.58  ? 369 ARG C CB  1 
ATOM   12103 C CG  . ARG C 1 369 ? 138.657 161.074 125.904 1.00 28.78  ? 369 ARG C CG  1 
ATOM   12104 C CD  . ARG C 1 369 ? 138.028 161.560 127.206 1.00 33.15  ? 369 ARG C CD  1 
ATOM   12105 N NE  . ARG C 1 369 ? 139.014 162.031 128.197 1.00 33.56  ? 369 ARG C NE  1 
ATOM   12106 C CZ  . ARG C 1 369 ? 139.243 161.516 129.390 1.00 29.11  ? 369 ARG C CZ  1 
ATOM   12107 N NH1 . ARG C 1 369 ? 140.022 162.085 130.251 1.00 21.79  ? 369 ARG C NH1 1 
ATOM   12108 N NH2 . ARG C 1 369 ? 138.709 160.398 129.774 1.00 31.11  ? 369 ARG C NH2 1 
ATOM   12109 N N   . HIS C 1 370 ? 141.061 157.145 125.543 1.00 31.40  ? 370 HIS C N   1 
ATOM   12110 C CA  . HIS C 1 370 ? 142.230 156.293 125.738 1.00 28.29  ? 370 HIS C CA  1 
ATOM   12111 C C   . HIS C 1 370 ? 142.748 155.664 124.438 1.00 28.19  ? 370 HIS C C   1 
ATOM   12112 O O   . HIS C 1 370 ? 143.953 155.348 124.393 1.00 36.87  ? 370 HIS C O   1 
ATOM   12113 C CB  . HIS C 1 370 ? 141.908 155.197 126.764 1.00 27.88  ? 370 HIS C CB  1 
ATOM   12114 C CG  . HIS C 1 370 ? 140.912 154.198 126.278 1.00 28.58  ? 370 HIS C CG  1 
ATOM   12115 N ND1 . HIS C 1 370 ? 141.288 152.971 125.769 1.00 27.18  ? 370 HIS C ND1 1 
ATOM   12116 C CD2 . HIS C 1 370 ? 139.564 154.239 126.214 1.00 32.07  ? 370 HIS C CD2 1 
ATOM   12117 C CE1 . HIS C 1 370 ? 140.213 152.296 125.416 1.00 33.53  ? 370 HIS C CE1 1 
ATOM   12118 N NE2 . HIS C 1 370 ? 139.140 153.053 125.679 1.00 36.00  ? 370 HIS C NE2 1 
ATOM   12119 N N   . ARG C 1 371 ? 141.894 155.491 123.423 1.00 31.10  ? 371 ARG C N   1 
ATOM   12120 C CA  . ARG C 1 371 ? 142.304 155.068 122.079 1.00 29.03  ? 371 ARG C CA  1 
ATOM   12121 C C   . ARG C 1 371 ? 142.975 156.196 121.287 1.00 31.75  ? 371 ARG C C   1 
ATOM   12122 O O   . ARG C 1 371 ? 143.879 155.921 120.512 1.00 28.95  ? 371 ARG C O   1 
ATOM   12123 C CB  . ARG C 1 371 ? 141.092 154.493 121.330 1.00 28.97  ? 371 ARG C CB  1 
ATOM   12124 C CG  . ARG C 1 371 ? 140.649 153.122 121.844 1.00 27.08  ? 371 ARG C CG  1 
ATOM   12125 C CD  . ARG C 1 371 ? 139.239 152.705 121.394 1.00 38.21  ? 371 ARG C CD  1 
ATOM   12126 N NE  . ARG C 1 371 ? 138.913 152.953 119.968 1.00 38.63  ? 371 ARG C NE  1 
ATOM   12127 C CZ  . ARG C 1 371 ? 139.410 152.364 118.895 1.00 38.70  ? 371 ARG C CZ  1 
ATOM   12128 N NH1 . ARG C 1 371 ? 138.912 152.607 117.723 1.00 36.80  ? 371 ARG C NH1 1 
ATOM   12129 N NH2 . ARG C 1 371 ? 140.397 151.524 118.952 1.00 37.65  ? 371 ARG C NH2 1 
ATOM   12130 N N   . MET C 1 372 ? 142.593 157.457 121.495 1.00 30.92  ? 372 MET C N   1 
ATOM   12131 C CA  . MET C 1 372 ? 143.222 158.607 120.834 1.00 20.81  ? 372 MET C CA  1 
ATOM   12132 C C   . MET C 1 372 ? 144.646 158.911 121.315 1.00 29.09  ? 372 MET C C   1 
ATOM   12133 O O   . MET C 1 372 ? 145.491 159.261 120.498 1.00 40.22  ? 372 MET C O   1 
ATOM   12134 C CB  . MET C 1 372 ? 142.355 159.861 120.968 1.00 20.21  ? 372 MET C CB  1 
ATOM   12135 C CG  . MET C 1 372 ? 141.078 159.756 120.139 1.00 34.13  ? 372 MET C CG  1 
ATOM   12136 S SD  . MET C 1 372 ? 140.136 161.288 119.985 1.00 47.10  ? 372 MET C SD  1 
ATOM   12137 C CE  . MET C 1 372 ? 139.468 161.412 121.660 1.00 27.45  ? 372 MET C CE  1 
ATOM   12138 N N   . VAL C 1 373 ? 144.960 158.766 122.607 1.00 27.91  ? 373 VAL C N   1 
ATOM   12139 C CA  . VAL C 1 373 ? 146.306 159.081 123.136 1.00 24.47  ? 373 VAL C CA  1 
ATOM   12140 C C   . VAL C 1 373 ? 147.390 158.082 122.720 1.00 27.27  ? 373 VAL C C   1 
ATOM   12141 O O   . VAL C 1 373 ? 148.570 158.384 122.850 1.00 33.42  ? 373 VAL C O   1 
ATOM   12142 C CB  . VAL C 1 373 ? 146.336 159.258 124.668 1.00 31.43  ? 373 VAL C CB  1 
ATOM   12143 C CG1 . VAL C 1 373 ? 145.441 160.401 125.121 1.00 27.63  ? 373 VAL C CG1 1 
ATOM   12144 C CG2 . VAL C 1 373 ? 145.966 157.994 125.433 1.00 19.54  ? 373 VAL C CG2 1 
ATOM   12145 N N   . VAL C 1 374 ? 147.013 156.906 122.215 1.00 21.51  ? 374 VAL C N   1 
ATOM   12146 C CA  . VAL C 1 374 ? 147.946 155.855 121.778 1.00 18.12  ? 374 VAL C CA  1 
ATOM   12147 C C   . VAL C 1 374 ? 148.176 155.828 120.260 1.00 23.25  ? 374 VAL C C   1 
ATOM   12148 O O   . VAL C 1 374 ? 148.844 154.930 119.758 1.00 31.19  ? 374 VAL C O   1 
ATOM   12149 C CB  . VAL C 1 374 ? 147.578 154.473 122.360 1.00 23.21  ? 374 VAL C CB  1 
ATOM   12150 C CG1 . VAL C 1 374 ? 147.564 154.498 123.889 1.00 29.00  ? 374 VAL C CG1 1 
ATOM   12151 C CG2 . VAL C 1 374 ? 146.234 153.947 121.872 1.00 23.29  ? 374 VAL C CG2 1 
ATOM   12152 N N   . LEU C 1 375 ? 147.662 156.811 119.515 1.00 25.16  ? 375 LEU C N   1 
ATOM   12153 C CA  . LEU C 1 375 ? 147.954 157.007 118.090 1.00 26.60  ? 375 LEU C CA  1 
ATOM   12154 C C   . LEU C 1 375 ? 149.320 157.680 117.888 1.00 27.96  ? 375 LEU C C   1 
ATOM   12155 O O   . LEU C 1 375 ? 149.723 158.495 118.706 1.00 30.74  ? 375 LEU C O   1 
ATOM   12156 C CB  . LEU C 1 375 ? 146.842 157.867 117.464 1.00 28.46  ? 375 LEU C CB  1 
ATOM   12157 C CG  . LEU C 1 375 ? 145.422 157.303 117.596 1.00 23.47  ? 375 LEU C CG  1 
ATOM   12158 C CD1 . LEU C 1 375 ? 144.434 158.257 116.952 1.00 23.02  ? 375 LEU C CD1 1 
ATOM   12159 C CD2 . LEU C 1 375 ? 145.274 155.938 116.941 1.00 26.31  ? 375 LEU C CD2 1 
ATOM   12160 N N   . GLU C 1 376 ? 150.027 157.435 116.784 1.00 31.53  ? 376 GLU C N   1 
ATOM   12161 C CA  . GLU C 1 376 ? 151.131 158.320 116.372 1.00 32.11  ? 376 GLU C CA  1 
ATOM   12162 C C   . GLU C 1 376 ? 150.594 159.680 115.889 1.00 26.50  ? 376 GLU C C   1 
ATOM   12163 O O   . GLU C 1 376 ? 149.555 159.704 115.226 1.00 34.91  ? 376 GLU C O   1 
ATOM   12164 C CB  . GLU C 1 376 ? 151.982 157.692 115.261 1.00 32.34  ? 376 GLU C CB  1 
ATOM   12165 C CG  . GLU C 1 376 ? 152.787 156.474 115.718 1.00 34.25  ? 376 GLU C CG  1 
ATOM   12166 C CD  . GLU C 1 376 ? 153.581 155.796 114.575 1.00 46.17  ? 376 GLU C CD  1 
ATOM   12167 O OE1 . GLU C 1 376 ? 153.776 156.410 113.499 1.00 44.27  ? 376 GLU C OE1 1 
ATOM   12168 O OE2 . GLU C 1 376 ? 154.008 154.638 114.773 1.00 46.32  ? 376 GLU C OE2 1 
ATOM   12169 N N   . PRO C 1 377 ? 151.282 160.809 116.156 1.00 22.39  ? 377 PRO C N   1 
ATOM   12170 C CA  . PRO C 1 377 ? 152.518 160.937 116.931 1.00 21.06  ? 377 PRO C CA  1 
ATOM   12171 C C   . PRO C 1 377 ? 152.268 161.123 118.442 1.00 24.64  ? 377 PRO C C   1 
ATOM   12172 O O   . PRO C 1 377 ? 153.241 161.329 119.144 1.00 28.92  ? 377 PRO C O   1 
ATOM   12173 C CB  . PRO C 1 377 ? 153.129 162.249 116.442 1.00 21.74  ? 377 PRO C CB  1 
ATOM   12174 C CG  . PRO C 1 377 ? 151.903 163.112 116.173 1.00 27.01  ? 377 PRO C CG  1 
ATOM   12175 C CD  . PRO C 1 377 ? 150.900 162.106 115.620 1.00 15.73  ? 377 PRO C CD  1 
ATOM   12176 N N   . LEU C 1 378 ? 151.014 161.042 118.915 1.00 30.89  ? 378 LEU C N   1 
ATOM   12177 C CA  . LEU C 1 378 ? 150.673 161.322 120.350 1.00 23.66  ? 378 LEU C CA  1 
ATOM   12178 C C   . LEU C 1 378 ? 151.315 160.301 121.300 1.00 28.91  ? 378 LEU C C   1 
ATOM   12179 O O   . LEU C 1 378 ? 151.818 160.698 122.342 1.00 35.48  ? 378 LEU C O   1 
ATOM   12180 C CB  . LEU C 1 378 ? 149.148 161.313 120.506 1.00 26.44  ? 378 LEU C CB  1 
ATOM   12181 C CG  . LEU C 1 378 ? 148.431 162.603 120.110 1.00 29.37  ? 378 LEU C CG  1 
ATOM   12182 C CD1 . LEU C 1 378 ? 148.677 162.942 118.648 1.00 26.46  ? 378 LEU C CD1 1 
ATOM   12183 C CD2 . LEU C 1 378 ? 146.938 162.496 120.385 1.00 29.92  ? 378 LEU C CD2 1 
ATOM   12184 N N   . ASN C 1 379 ? 151.368 159.023 120.940 1.00 27.56  ? 379 ASN C N   1 
ATOM   12185 C CA  . ASN C 1 379 ? 151.975 157.966 121.736 1.00 13.97  ? 379 ASN C CA  1 
ATOM   12186 C C   . ASN C 1 379 ? 153.448 158.251 122.080 1.00 19.97  ? 379 ASN C C   1 
ATOM   12187 O O   . ASN C 1 379 ? 153.808 158.322 123.250 1.00 36.01  ? 379 ASN C O   1 
ATOM   12188 C CB  . ASN C 1 379 ? 151.807 156.649 120.970 1.00 20.00  ? 379 ASN C CB  1 
ATOM   12189 C CG  . ASN C 1 379 ? 152.224 155.439 121.783 1.00 33.20  ? 379 ASN C CG  1 
ATOM   12190 O OD1 . ASN C 1 379 ? 151.754 155.207 122.881 1.00 36.70  ? 379 ASN C OD1 1 
ATOM   12191 N ND2 . ASN C 1 379 ? 153.119 154.634 121.279 1.00 30.42  ? 379 ASN C ND2 1 
ATOM   12192 N N   . LYS C 1 380 ? 154.309 158.452 121.074 1.00 32.46  ? 380 LYS C N   1 
ATOM   12193 C CA  . LYS C 1 380 ? 155.735 158.732 121.286 1.00 24.60  ? 380 LYS C CA  1 
ATOM   12194 C C   . LYS C 1 380 ? 155.949 160.125 121.875 1.00 22.87  ? 380 LYS C C   1 
ATOM   12195 O O   . LYS C 1 380 ? 156.830 160.298 122.707 1.00 33.77  ? 380 LYS C O   1 
ATOM   12196 C CB  . LYS C 1 380 ? 156.538 158.494 119.989 1.00 27.43  ? 380 LYS C CB  1 
ATOM   12197 C CG  . LYS C 1 380 ? 158.053 158.644 120.247 1.00 36.01  ? 380 LYS C CG  1 
ATOM   12198 C CD  . LYS C 1 380 ? 158.935 158.736 119.001 1.00 32.56  ? 380 LYS C CD  1 
ATOM   12199 C CE  . LYS C 1 380 ? 160.357 159.098 119.459 1.00 35.04  ? 380 LYS C CE  1 
ATOM   12200 N NZ  . LYS C 1 380 ? 161.289 159.307 118.325 1.00 34.60  ? 380 LYS C NZ  1 
ATOM   12201 N N   . LEU C 1 381 ? 155.131 161.105 121.508 1.00 16.57  ? 381 LEU C N   1 
ATOM   12202 C CA  . LEU C 1 381 ? 155.191 162.452 122.071 1.00 19.42  ? 381 LEU C CA  1 
ATOM   12203 C C   . LEU C 1 381 ? 154.887 162.458 123.575 1.00 23.99  ? 381 LEU C C   1 
ATOM   12204 O O   . LEU C 1 381 ? 155.606 163.060 124.362 1.00 35.47  ? 381 LEU C O   1 
ATOM   12205 C CB  . LEU C 1 381 ? 154.216 163.332 121.273 1.00 25.64  ? 381 LEU C CB  1 
ATOM   12206 C CG  . LEU C 1 381 ? 154.159 164.796 121.718 1.00 30.04  ? 381 LEU C CG  1 
ATOM   12207 C CD1 . LEU C 1 381 ? 155.475 165.505 121.452 1.00 28.72  ? 381 LEU C CD1 1 
ATOM   12208 C CD2 . LEU C 1 381 ? 153.052 165.506 120.950 1.00 27.08  ? 381 LEU C CD2 1 
ATOM   12209 N N   . LEU C 1 382 ? 153.851 161.744 124.006 1.00 30.48  ? 382 LEU C N   1 
ATOM   12210 C CA  . LEU C 1 382 ? 153.518 161.579 125.417 1.00 18.83  ? 382 LEU C CA  1 
ATOM   12211 C C   . LEU C 1 382 ? 154.552 160.742 126.161 1.00 20.21  ? 382 LEU C C   1 
ATOM   12212 O O   . LEU C 1 382 ? 154.846 161.058 127.307 1.00 35.02  ? 382 LEU C O   1 
ATOM   12213 C CB  . LEU C 1 382 ? 152.112 160.985 125.552 1.00 20.59  ? 382 LEU C CB  1 
ATOM   12214 C CG  . LEU C 1 382 ? 150.997 161.999 125.254 1.00 19.70  ? 382 LEU C CG  1 
ATOM   12215 C CD1 . LEU C 1 382 ? 149.678 161.262 125.092 1.00 16.69  ? 382 LEU C CD1 1 
ATOM   12216 C CD2 . LEU C 1 382 ? 150.858 163.030 126.374 1.00 22.15  ? 382 LEU C CD2 1 
ATOM   12217 N N   . GLN C 1 383 ? 155.187 159.788 125.477 1.00 23.11  ? 383 GLN C N   1 
ATOM   12218 C CA  . GLN C 1 383 ? 156.285 159.025 126.132 1.00 16.96  ? 383 GLN C CA  1 
ATOM   12219 C C   . GLN C 1 383 ? 157.481 159.972 126.338 1.00 18.80  ? 383 GLN C C   1 
ATOM   12220 O O   . GLN C 1 383 ? 158.032 159.967 127.457 1.00 36.27  ? 383 GLN C O   1 
ATOM   12221 C CB  . GLN C 1 383 ? 156.584 157.748 125.336 1.00 20.50  ? 383 GLN C CB  1 
ATOM   12222 C CG  . GLN C 1 383 ? 157.539 156.795 126.067 1.00 27.15  ? 383 GLN C CG  1 
ATOM   12223 C CD  . GLN C 1 383 ? 157.017 156.394 127.424 1.00 34.10  ? 383 GLN C CD  1 
ATOM   12224 O OE1 . GLN C 1 383 ? 155.816 156.418 127.683 1.00 37.34  ? 383 GLN C OE1 1 
ATOM   12225 N NE2 . GLN C 1 383 ? 157.925 156.011 128.307 1.00 27.25  ? 383 GLN C NE2 1 
ATOM   12226 N N   . GLU C 1 384 ? 157.868 160.758 125.322 1.00 29.60  ? 384 GLU C N   1 
ATOM   12227 C CA  . GLU C 1 384 ? 158.927 161.757 125.467 1.00 29.50  ? 384 GLU C CA  1 
ATOM   12228 C C   . GLU C 1 384 ? 158.663 162.746 126.607 1.00 28.08  ? 384 GLU C C   1 
ATOM   12229 O O   . GLU C 1 384 ? 159.583 163.085 127.350 1.00 34.91  ? 384 GLU C O   1 
ATOM   12230 C CB  . GLU C 1 384 ? 159.084 162.526 124.144 1.00 32.49  ? 384 GLU C CB  1 
ATOM   12231 C CG  . GLU C 1 384 ? 159.955 161.780 123.125 1.00 33.51  ? 384 GLU C CG  1 
ATOM   12232 C CD  . GLU C 1 384 ? 161.459 161.898 123.395 1.00 44.15  ? 384 GLU C CD  1 
ATOM   12233 O OE1 . GLU C 1 384 ? 161.870 162.562 124.375 1.00 46.48  ? 384 GLU C OE1 1 
ATOM   12234 O OE2 . GLU C 1 384 ? 162.243 161.337 122.599 1.00 43.34  ? 384 GLU C OE2 1 
ATOM   12235 N N   . LYS C 1 385 ? 157.417 163.199 126.780 1.00 30.69  ? 385 LYS C N   1 
ATOM   12236 C CA  . LYS C 1 385 ? 157.017 164.044 127.907 1.00 22.34  ? 385 LYS C CA  1 
ATOM   12237 C C   . LYS C 1 385 ? 157.075 163.293 129.235 1.00 24.81  ? 385 LYS C C   1 
ATOM   12238 O O   . LYS C 1 385 ? 157.573 163.840 130.211 1.00 26.52  ? 385 LYS C O   1 
ATOM   12239 C CB  . LYS C 1 385 ? 155.616 164.607 127.668 1.00 24.31  ? 385 LYS C CB  1 
ATOM   12240 C CG  . LYS C 1 385 ? 155.563 165.664 126.565 1.00 22.06  ? 385 LYS C CG  1 
ATOM   12241 C CD  . LYS C 1 385 ? 154.126 166.083 126.247 1.00 23.09  ? 385 LYS C CD  1 
ATOM   12242 C CE  . LYS C 1 385 ? 154.055 167.078 125.089 1.00 25.88  ? 385 LYS C CE  1 
ATOM   12243 N NZ  . LYS C 1 385 ? 154.719 168.353 125.398 1.00 28.25  ? 385 LYS C NZ  1 
ATOM   12244 N N   . TRP C 1 386 ? 156.614 162.045 129.290 1.00 20.72  ? 386 TRP C N   1 
ATOM   12245 C CA  . TRP C 1 386 ? 156.714 161.212 130.490 1.00 13.26  ? 386 TRP C CA  1 
ATOM   12246 C C   . TRP C 1 386 ? 158.166 160.974 130.905 1.00 25.03  ? 386 TRP C C   1 
ATOM   12247 O O   . TRP C 1 386 ? 158.512 161.195 132.059 1.00 38.22  ? 386 TRP C O   1 
ATOM   12248 C CB  . TRP C 1 386 ? 155.991 159.873 130.306 1.00 23.45  ? 386 TRP C CB  1 
ATOM   12249 C CG  . TRP C 1 386 ? 156.081 158.994 131.520 1.00 22.59  ? 386 TRP C CG  1 
ATOM   12250 C CD1 . TRP C 1 386 ? 157.039 158.071 131.745 1.00 26.97  ? 386 TRP C CD1 1 
ATOM   12251 C CD2 . TRP C 1 386 ? 155.326 159.078 132.766 1.00 28.25  ? 386 TRP C CD2 1 
ATOM   12252 N NE1 . TRP C 1 386 ? 156.957 157.620 133.044 1.00 31.92  ? 386 TRP C NE1 1 
ATOM   12253 C CE2 . TRP C 1 386 ? 155.927 158.225 133.728 1.00 27.81  ? 386 TRP C CE2 1 
ATOM   12254 C CE3 . TRP C 1 386 ? 154.205 159.818 133.189 1.00 26.85  ? 386 TRP C CE3 1 
ATOM   12255 C CZ2 . TRP C 1 386 ? 155.452 158.120 135.044 1.00 23.15  ? 386 TRP C CZ2 1 
ATOM   12256 C CZ3 . TRP C 1 386 ? 153.725 159.739 134.506 1.00 19.05  ? 386 TRP C CZ3 1 
ATOM   12257 C CH2 . TRP C 1 386 ? 154.343 158.886 135.433 1.00 26.45  ? 386 TRP C CH2 1 
ATOM   12258 N N   . ASP C 1 387 ? 159.042 160.581 129.989 1.00 29.94  ? 387 ASP C N   1 
ATOM   12259 C CA  . ASP C 1 387 ? 160.438 160.271 130.293 1.00 26.01  ? 387 ASP C CA  1 
ATOM   12260 C C   . ASP C 1 387 ? 161.214 161.464 130.877 1.00 28.46  ? 387 ASP C C   1 
ATOM   12261 O O   . ASP C 1 387 ? 162.088 161.267 131.711 1.00 38.32  ? 387 ASP C O   1 
ATOM   12262 C CB  . ASP C 1 387 ? 161.145 159.743 129.038 1.00 28.09  ? 387 ASP C CB  1 
ATOM   12263 C CG  . ASP C 1 387 ? 160.674 158.365 128.553 1.00 35.08  ? 387 ASP C CG  1 
ATOM   12264 O OD1 . ASP C 1 387 ? 159.937 157.662 129.277 1.00 37.03  ? 387 ASP C OD1 1 
ATOM   12265 O OD2 . ASP C 1 387 ? 161.115 157.937 127.463 1.00 40.49  ? 387 ASP C OD2 1 
ATOM   12266 N N   . ARG C 1 388 ? 160.874 162.703 130.514 1.00 36.49  ? 388 ARG C N   1 
ATOM   12267 C CA  . ARG C 1 388 ? 161.461 163.916 131.111 1.00 35.98  ? 388 ARG C CA  1 
ATOM   12268 C C   . ARG C 1 388 ? 160.741 164.440 132.360 1.00 38.06  ? 388 ARG C C   1 
ATOM   12269 O O   . ARG C 1 388 ? 161.207 165.401 132.963 1.00 49.12  ? 388 ARG C O   1 
ATOM   12270 C CB  . ARG C 1 388 ? 161.693 164.985 130.034 1.00 34.95  ? 388 ARG C CB  1 
ATOM   12271 C CG  . ARG C 1 388 ? 160.417 165.643 129.505 1.00 39.96  ? 388 ARG C CG  1 
ATOM   12272 C CD  . ARG C 1 388 ? 160.684 166.511 128.271 1.00 42.49  ? 388 ARG C CD  1 
ATOM   12273 N NE  . ARG C 1 388 ? 161.106 165.702 127.108 1.00 48.12  ? 388 ARG C NE  1 
ATOM   12274 C CZ  . ARG C 1 388 ? 162.044 165.993 126.227 1.00 52.15  ? 388 ARG C CZ  1 
ATOM   12275 N NH1 . ARG C 1 388 ? 162.347 165.176 125.264 1.00 45.50  ? 388 ARG C NH1 1 
ATOM   12276 N NH2 . ARG C 1 388 ? 162.718 167.103 126.275 1.00 49.05  ? 388 ARG C NH2 1 
ATOM   12277 N N   . LEU C 1 389 ? 159.633 163.820 132.769 1.00 29.75  ? 389 LEU C N   1 
ATOM   12278 C CA  . LEU C 1 389 ? 158.843 164.183 133.954 1.00 22.38  ? 389 LEU C CA  1 
ATOM   12279 C C   . LEU C 1 389 ? 158.743 163.074 135.004 1.00 27.58  ? 389 LEU C C   1 
ATOM   12280 O O   . LEU C 1 389 ? 158.333 163.347 136.125 1.00 35.04  ? 389 LEU C O   1 
ATOM   12281 C CB  . LEU C 1 389 ? 157.438 164.621 133.525 1.00 28.34  ? 389 LEU C CB  1 
ATOM   12282 C CG  . LEU C 1 389 ? 157.388 165.995 132.851 1.00 27.26  ? 389 LEU C CG  1 
ATOM   12283 C CD1 . LEU C 1 389 ? 156.008 166.225 132.255 1.00 27.99  ? 389 LEU C CD1 1 
ATOM   12284 C CD2 . LEU C 1 389 ? 157.668 167.111 133.852 1.00 26.30  ? 389 LEU C CD2 1 
ATOM   12285 N N   . VAL C 1 390 ? 159.140 161.842 134.702 1.00 24.53  ? 390 VAL C N   1 
ATOM   12286 C CA  . VAL C 1 390 ? 159.047 160.703 135.626 1.00 26.50  ? 390 VAL C CA  1 
ATOM   12287 C C   . VAL C 1 390 ? 159.798 160.929 136.942 1.00 28.24  ? 390 VAL C C   1 
ATOM   12288 O O   . VAL C 1 390 ? 159.331 160.528 138.001 1.00 37.10  ? 390 VAL C O   1 
ATOM   12289 C CB  . VAL C 1 390 ? 159.489 159.417 134.909 1.00 28.26  ? 390 VAL C CB  1 
ATOM   12290 C CG1 . VAL C 1 390 ? 160.973 159.387 134.544 1.00 27.47  ? 390 VAL C CG1 1 
ATOM   12291 C CG2 . VAL C 1 390 ? 159.187 158.177 135.745 1.00 30.02  ? 390 VAL C CG2 1 
ATOM   12292 N N   . SER C 1 391 ? 160.918 161.650 136.919 1.00 31.34  ? 391 SER C N   1 
ATOM   12293 C CA  . SER C 1 391 ? 161.659 162.033 138.125 1.00 23.98  ? 391 SER C CA  1 
ATOM   12294 C C   . SER C 1 391 ? 160.875 163.019 139.004 1.00 26.49  ? 391 SER C C   1 
ATOM   12295 O O   . SER C 1 391 ? 160.886 162.887 140.225 1.00 34.89  ? 391 SER C O   1 
ATOM   12296 C CB  . SER C 1 391 ? 163.013 162.618 137.732 1.00 24.82  ? 391 SER C CB  1 
ATOM   12297 O OG  . SER C 1 391 ? 162.855 163.734 136.877 1.00 35.23  ? 391 SER C OG  1 
ATOM   12298 N N   . ARG C 1 392 ? 160.140 163.965 138.406 1.00 28.35  ? 392 ARG C N   1 
ATOM   12299 C CA  . ARG C 1 392 ? 159.218 164.874 139.100 1.00 20.04  ? 392 ARG C CA  1 
ATOM   12300 C C   . ARG C 1 392 ? 158.002 164.143 139.655 1.00 20.35  ? 392 ARG C C   1 
ATOM   12301 O O   . ARG C 1 392 ? 157.599 164.417 140.775 1.00 35.11  ? 392 ARG C O   1 
ATOM   12302 C CB  . ARG C 1 392 ? 158.824 166.018 138.161 1.00 27.91  ? 392 ARG C CB  1 
ATOM   12303 C CG  . ARG C 1 392 ? 157.911 167.044 138.844 1.00 22.94  ? 392 ARG C CG  1 
ATOM   12304 C CD  . ARG C 1 392 ? 157.709 168.296 137.994 1.00 33.01  ? 392 ARG C CD  1 
ATOM   12305 N NE  . ARG C 1 392 ? 158.954 169.090 137.892 1.00 45.97  ? 392 ARG C NE  1 
ATOM   12306 C CZ  . ARG C 1 392 ? 159.136 170.360 138.205 1.00 42.44  ? 392 ARG C CZ  1 
ATOM   12307 N NH1 . ARG C 1 392 ? 160.321 170.884 138.150 1.00 39.39  ? 392 ARG C NH1 1 
ATOM   12308 N NH2 . ARG C 1 392 ? 158.165 171.139 138.572 1.00 37.13  ? 392 ARG C NH2 1 
ATOM   12309 N N   . PHE C 1 393 ? 157.463 163.161 138.943 1.00 24.34  ? 393 PHE C N   1 
ATOM   12310 C CA  . PHE C 1 393 ? 156.379 162.315 139.439 1.00 10.16  ? 393 PHE C CA  1 
ATOM   12311 C C   . PHE C 1 393 ? 156.758 161.581 140.734 1.00 17.33  ? 393 PHE C C   1 
ATOM   12312 O O   . PHE C 1 393 ? 156.031 161.622 141.722 1.00 29.00  ? 393 PHE C O   1 
ATOM   12313 C CB  . PHE C 1 393 ? 155.966 161.317 138.354 1.00 14.00  ? 393 PHE C CB  1 
ATOM   12314 C CG  . PHE C 1 393 ? 154.720 160.536 138.696 1.00 17.89  ? 393 PHE C CG  1 
ATOM   12315 C CD1 . PHE C 1 393 ? 153.455 161.117 138.490 1.00 10.85  ? 393 PHE C CD1 1 
ATOM   12316 C CD2 . PHE C 1 393 ? 154.813 159.256 139.266 1.00 16.94  ? 393 PHE C CD2 1 
ATOM   12317 C CE1 . PHE C 1 393 ? 152.293 160.414 138.835 1.00 9.51   ? 393 PHE C CE1 1 
ATOM   12318 C CE2 . PHE C 1 393 ? 153.647 158.562 139.629 1.00 17.30  ? 393 PHE C CE2 1 
ATOM   12319 C CZ  . PHE C 1 393 ? 152.390 159.139 139.405 1.00 12.15  ? 393 PHE C CZ  1 
ATOM   12320 N N   . PHE C 1 394 ? 157.929 160.948 140.762 1.00 26.46  ? 394 PHE C N   1 
ATOM   12321 C CA  . PHE C 1 394 ? 158.400 160.236 141.944 1.00 15.58  ? 394 PHE C CA  1 
ATOM   12322 C C   . PHE C 1 394 ? 158.965 161.152 143.040 1.00 15.63  ? 394 PHE C C   1 
ATOM   12323 O O   . PHE C 1 394 ? 158.869 160.799 144.209 1.00 24.16  ? 394 PHE C O   1 
ATOM   12324 C CB  . PHE C 1 394 ? 159.326 159.097 141.530 1.00 17.93  ? 394 PHE C CB  1 
ATOM   12325 C CG  . PHE C 1 394 ? 158.567 157.968 140.860 1.00 19.60  ? 394 PHE C CG  1 
ATOM   12326 C CD1 . PHE C 1 394 ? 157.624 157.230 141.598 1.00 23.67  ? 394 PHE C CD1 1 
ATOM   12327 C CD2 . PHE C 1 394 ? 158.774 157.661 139.506 1.00 22.61  ? 394 PHE C CD2 1 
ATOM   12328 C CE1 . PHE C 1 394 ? 156.891 156.200 140.987 1.00 26.07  ? 394 PHE C CE1 1 
ATOM   12329 C CE2 . PHE C 1 394 ? 158.053 156.620 138.898 1.00 18.06  ? 394 PHE C CE2 1 
ATOM   12330 C CZ  . PHE C 1 394 ? 157.115 155.892 139.639 1.00 20.79  ? 394 PHE C CZ  1 
ATOM   12331 N N   . PHE C 1 395 ? 159.414 162.369 142.733 1.00 21.41  ? 395 PHE C N   1 
ATOM   12332 C CA  . PHE C 1 395 ? 159.607 163.413 143.736 1.00 16.85  ? 395 PHE C CA  1 
ATOM   12333 C C   . PHE C 1 395 ? 158.287 163.845 144.397 1.00 21.55  ? 395 PHE C C   1 
ATOM   12334 O O   . PHE C 1 395 ? 158.216 163.954 145.619 1.00 29.03  ? 395 PHE C O   1 
ATOM   12335 C CB  . PHE C 1 395 ? 160.319 164.608 143.103 1.00 19.00  ? 395 PHE C CB  1 
ATOM   12336 C CG  . PHE C 1 395 ? 160.454 165.791 144.033 1.00 25.43  ? 395 PHE C CG  1 
ATOM   12337 C CD1 . PHE C 1 395 ? 161.420 165.771 145.053 1.00 20.72  ? 395 PHE C CD1 1 
ATOM   12338 C CD2 . PHE C 1 395 ? 159.594 166.898 143.909 1.00 23.55  ? 395 PHE C CD2 1 
ATOM   12339 C CE1 . PHE C 1 395 ? 161.527 166.851 145.941 1.00 25.07  ? 395 PHE C CE1 1 
ATOM   12340 C CE2 . PHE C 1 395 ? 159.708 167.979 144.790 1.00 24.62  ? 395 PHE C CE2 1 
ATOM   12341 C CZ  . PHE C 1 395 ? 160.675 167.958 145.809 1.00 26.14  ? 395 PHE C CZ  1 
ATOM   12342 N N   . ASN C 1 396 ? 157.215 164.045 143.630 1.00 30.67  ? 396 ASN C N   1 
ATOM   12343 C CA  . ASN C 1 396 ? 155.889 164.354 144.168 1.00 18.26  ? 396 ASN C CA  1 
ATOM   12344 C C   . ASN C 1 396 ? 155.350 163.216 145.055 1.00 17.73  ? 396 ASN C C   1 
ATOM   12345 O O   . ASN C 1 396 ? 154.830 163.476 146.136 1.00 28.15  ? 396 ASN C O   1 
ATOM   12346 C CB  . ASN C 1 396 ? 154.921 164.644 143.012 1.00 17.22  ? 396 ASN C CB  1 
ATOM   12347 C CG  . ASN C 1 396 ? 155.200 165.920 142.247 1.00 20.73  ? 396 ASN C CG  1 
ATOM   12348 O OD1 . ASN C 1 396 ? 155.952 166.785 142.659 1.00 28.69  ? 396 ASN C OD1 1 
ATOM   12349 N ND2 . ASN C 1 396 ? 154.564 166.096 141.113 1.00 26.65  ? 396 ASN C ND2 1 
ATOM   12350 N N   . PHE C 1 397 ? 155.527 161.959 144.643 1.00 19.54  ? 397 PHE C N   1 
ATOM   12351 C CA  . PHE C 1 397 ? 155.223 160.776 145.447 1.00 8.69   ? 397 PHE C CA  1 
ATOM   12352 C C   . PHE C 1 397 ? 156.027 160.728 146.747 1.00 27.68  ? 397 PHE C C   1 
ATOM   12353 O O   . PHE C 1 397 ? 155.453 160.508 147.808 1.00 36.59  ? 397 PHE C O   1 
ATOM   12354 C CB  . PHE C 1 397 ? 155.508 159.519 144.626 1.00 13.60  ? 397 PHE C CB  1 
ATOM   12355 C CG  . PHE C 1 397 ? 155.448 158.222 145.399 1.00 23.85  ? 397 PHE C CG  1 
ATOM   12356 C CD1 . PHE C 1 397 ? 154.266 157.833 146.051 1.00 23.01  ? 397 PHE C CD1 1 
ATOM   12357 C CD2 . PHE C 1 397 ? 156.585 157.400 145.489 1.00 26.90  ? 397 PHE C CD2 1 
ATOM   12358 C CE1 . PHE C 1 397 ? 154.193 156.603 146.719 1.00 16.03  ? 397 PHE C CE1 1 
ATOM   12359 C CE2 . PHE C 1 397 ? 156.526 156.188 146.195 1.00 28.46  ? 397 PHE C CE2 1 
ATOM   12360 C CZ  . PHE C 1 397 ? 155.325 155.781 146.793 1.00 27.22  ? 397 PHE C CZ  1 
ATOM   12361 N N   . ALA C 1 398 ? 157.342 160.958 146.699 1.00 30.91  ? 398 ALA C N   1 
ATOM   12362 C CA  . ALA C 1 398 ? 158.193 160.979 147.880 1.00 11.33  ? 398 ALA C CA  1 
ATOM   12363 C C   . ALA C 1 398 ? 157.791 162.077 148.875 1.00 19.45  ? 398 ALA C C   1 
ATOM   12364 O O   . ALA C 1 398 ? 157.763 161.834 150.076 1.00 32.40  ? 398 ALA C O   1 
ATOM   12365 C CB  . ALA C 1 398 ? 159.642 161.140 147.423 1.00 23.88  ? 398 ALA C CB  1 
ATOM   12366 N N   . CYS C 1 399 ? 157.409 163.264 148.403 1.00 26.04  ? 399 CYS C N   1 
ATOM   12367 C CA  . CYS C 1 399 ? 156.893 164.328 149.261 1.00 23.70  ? 399 CYS C CA  1 
ATOM   12368 C C   . CYS C 1 399 ? 155.557 163.953 149.909 1.00 22.52  ? 399 CYS C C   1 
ATOM   12369 O O   . CYS C 1 399 ? 155.354 164.242 151.087 1.00 33.30  ? 399 CYS C O   1 
ATOM   12370 C CB  . CYS C 1 399 ? 156.785 165.633 148.466 1.00 27.96  ? 399 CYS C CB  1 
ATOM   12371 S SG  . CYS C 1 399 ? 158.436 166.145 147.949 1.00 38.78  ? 399 CYS C SG  1 
ATOM   12372 N N   . TYR C 1 400 ? 154.664 163.261 149.193 1.00 20.58  ? 400 TYR C N   1 
ATOM   12373 C CA  . TYR C 1 400 ? 153.411 162.781 149.773 1.00 14.04  ? 400 TYR C CA  1 
ATOM   12374 C C   . TYR C 1 400 ? 153.627 161.619 150.752 1.00 21.68  ? 400 TYR C C   1 
ATOM   12375 O O   . TYR C 1 400 ? 153.004 161.588 151.805 1.00 31.27  ? 400 TYR C O   1 
ATOM   12376 C CB  . TYR C 1 400 ? 152.395 162.443 148.677 1.00 11.33  ? 400 TYR C CB  1 
ATOM   12377 C CG  . TYR C 1 400 ? 150.973 162.367 149.204 1.00 20.38  ? 400 TYR C CG  1 
ATOM   12378 C CD1 . TYR C 1 400 ? 150.332 163.546 149.622 1.00 19.76  ? 400 TYR C CD1 1 
ATOM   12379 C CD2 . TYR C 1 400 ? 150.296 161.142 149.313 1.00 5.90   ? 400 TYR C CD2 1 
ATOM   12380 C CE1 . TYR C 1 400 ? 149.045 163.499 150.171 1.00 19.78  ? 400 TYR C CE1 1 
ATOM   12381 C CE2 . TYR C 1 400 ? 148.992 161.092 149.839 1.00 6.35   ? 400 TYR C CE2 1 
ATOM   12382 C CZ  . TYR C 1 400 ? 148.370 162.275 150.275 1.00 22.64  ? 400 TYR C CZ  1 
ATOM   12383 O OH  . TYR C 1 400 ? 147.119 162.270 150.799 1.00 31.03  ? 400 TYR C OH  1 
ATOM   12384 N N   . LEU C 1 401 ? 154.571 160.713 150.482 1.00 15.73  ? 401 LEU C N   1 
ATOM   12385 C CA  . LEU C 1 401 ? 155.005 159.696 151.439 1.00 18.62  ? 401 LEU C CA  1 
ATOM   12386 C C   . LEU C 1 401 ? 155.561 160.313 152.717 1.00 16.93  ? 401 LEU C C   1 
ATOM   12387 O O   . LEU C 1 401 ? 155.183 159.878 153.796 1.00 32.21  ? 401 LEU C O   1 
ATOM   12388 C CB  . LEU C 1 401 ? 156.103 158.799 150.843 1.00 25.57  ? 401 LEU C CB  1 
ATOM   12389 C CG  . LEU C 1 401 ? 155.639 157.521 150.149 1.00 24.97  ? 401 LEU C CG  1 
ATOM   12390 C CD1 . LEU C 1 401 ? 156.894 156.771 149.712 1.00 25.86  ? 401 LEU C CD1 1 
ATOM   12391 C CD2 . LEU C 1 401 ? 154.859 156.586 151.069 1.00 20.32  ? 401 LEU C CD2 1 
ATOM   12392 N N   . VAL C 1 402 ? 156.437 161.313 152.631 1.00 25.55  ? 402 VAL C N   1 
ATOM   12393 C CA  . VAL C 1 402 ? 156.991 161.982 153.814 1.00 22.25  ? 402 VAL C CA  1 
ATOM   12394 C C   . VAL C 1 402 ? 155.893 162.704 154.594 1.00 21.72  ? 402 VAL C C   1 
ATOM   12395 O O   . VAL C 1 402 ? 155.806 162.541 155.806 1.00 35.64  ? 402 VAL C O   1 
ATOM   12396 C CB  . VAL C 1 402 ? 158.149 162.914 153.424 1.00 26.62  ? 402 VAL C CB  1 
ATOM   12397 C CG1 . VAL C 1 402 ? 158.596 163.836 154.560 1.00 25.52  ? 402 VAL C CG1 1 
ATOM   12398 C CG2 . VAL C 1 402 ? 159.363 162.079 153.013 1.00 21.81  ? 402 VAL C CG2 1 
ATOM   12399 N N   . TYR C 1 403 ? 154.996 163.422 153.926 1.00 24.12  ? 403 TYR C N   1 
ATOM   12400 C CA  . TYR C 1 403 ? 153.819 164.004 154.562 1.00 20.00  ? 403 TYR C CA  1 
ATOM   12401 C C   . TYR C 1 403 ? 152.951 162.943 155.257 1.00 22.16  ? 403 TYR C C   1 
ATOM   12402 O O   . TYR C 1 403 ? 152.633 163.112 156.425 1.00 35.89  ? 403 TYR C O   1 
ATOM   12403 C CB  . TYR C 1 403 ? 153.058 164.836 153.524 1.00 20.24  ? 403 TYR C CB  1 
ATOM   12404 C CG  . TYR C 1 403 ? 151.656 165.260 153.905 1.00 26.76  ? 403 TYR C CG  1 
ATOM   12405 C CD1 . TYR C 1 403 ? 151.432 166.338 154.785 1.00 19.73  ? 403 TYR C CD1 1 
ATOM   12406 C CD2 . TYR C 1 403 ? 150.563 164.575 153.342 1.00 29.12  ? 403 TYR C CD2 1 
ATOM   12407 C CE1 . TYR C 1 403 ? 150.113 166.763 155.052 1.00 22.70  ? 403 TYR C CE1 1 
ATOM   12408 C CE2 . TYR C 1 403 ? 149.251 164.991 153.612 1.00 27.04  ? 403 TYR C CE2 1 
ATOM   12409 C CZ  . TYR C 1 403 ? 149.024 166.110 154.438 1.00 27.71  ? 403 TYR C CZ  1 
ATOM   12410 O OH  . TYR C 1 403 ? 147.757 166.578 154.598 1.00 37.47  ? 403 TYR C OH  1 
ATOM   12411 N N   . MET C 1 404 ? 152.626 161.820 154.617 1.00 23.17  ? 404 MET C N   1 
ATOM   12412 C CA  . MET C 1 404 ? 151.813 160.759 155.220 1.00 18.24  ? 404 MET C CA  1 
ATOM   12413 C C   . MET C 1 404 ? 152.521 159.944 156.300 1.00 18.31  ? 404 MET C C   1 
ATOM   12414 O O   . MET C 1 404 ? 151.872 159.491 157.241 1.00 27.92  ? 404 MET C O   1 
ATOM   12415 C CB  . MET C 1 404 ? 151.241 159.826 154.144 1.00 24.33  ? 404 MET C CB  1 
ATOM   12416 C CG  . MET C 1 404 ? 150.106 160.475 153.356 1.00 8.67   ? 404 MET C CG  1 
ATOM   12417 S SD  . MET C 1 404 ? 148.788 161.247 154.335 1.00 25.37  ? 404 MET C SD  1 
ATOM   12418 C CE  . MET C 1 404 ? 148.350 159.913 155.470 1.00 19.69  ? 404 MET C CE  1 
ATOM   12419 N N   . PHE C 1 405 ? 153.839 159.791 156.235 1.00 34.05  ? 405 PHE C N   1 
ATOM   12420 C CA  . PHE C 1 405 ? 154.646 159.255 157.326 1.00 19.76  ? 405 PHE C CA  1 
ATOM   12421 C C   . PHE C 1 405 ? 154.580 160.167 158.558 1.00 24.21  ? 405 PHE C C   1 
ATOM   12422 O O   . PHE C 1 405 ? 154.238 159.695 159.638 1.00 35.22  ? 405 PHE C O   1 
ATOM   12423 C CB  . PHE C 1 405 ? 156.084 159.053 156.844 1.00 22.76  ? 405 PHE C CB  1 
ATOM   12424 C CG  . PHE C 1 405 ? 157.033 158.628 157.939 1.00 37.81  ? 405 PHE C CG  1 
ATOM   12425 C CD1 . PHE C 1 405 ? 157.057 157.294 158.378 1.00 36.47  ? 405 PHE C CD1 1 
ATOM   12426 C CD2 . PHE C 1 405 ? 157.868 159.578 158.558 1.00 37.17  ? 405 PHE C CD2 1 
ATOM   12427 C CE1 . PHE C 1 405 ? 157.901 156.910 159.429 1.00 32.69  ? 405 PHE C CE1 1 
ATOM   12428 C CE2 . PHE C 1 405 ? 158.707 159.194 159.618 1.00 35.47  ? 405 PHE C CE2 1 
ATOM   12429 C CZ  . PHE C 1 405 ? 158.724 157.860 160.052 1.00 35.71  ? 405 PHE C CZ  1 
ATOM   12430 N N   . ILE C 1 406 ? 154.810 161.475 158.407 1.00 26.15  ? 406 ILE C N   1 
ATOM   12431 C CA  . ILE C 1 406 ? 154.673 162.450 159.501 1.00 25.43  ? 406 ILE C CA  1 
ATOM   12432 C C   . ILE C 1 406 ? 153.240 162.457 160.039 1.00 22.60  ? 406 ILE C C   1 
ATOM   12433 O O   . ILE C 1 406 ? 153.048 162.398 161.246 1.00 41.51  ? 406 ILE C O   1 
ATOM   12434 C CB  . ILE C 1 406 ? 155.134 163.856 159.055 1.00 32.73  ? 406 ILE C CB  1 
ATOM   12435 C CG1 . ILE C 1 406 ? 156.656 163.866 158.801 1.00 27.65  ? 406 ILE C CG1 1 
ATOM   12436 C CG2 . ILE C 1 406 ? 154.788 164.945 160.087 1.00 29.96  ? 406 ILE C CG2 1 
ATOM   12437 C CD1 . ILE C 1 406 ? 157.124 165.055 157.960 1.00 29.37  ? 406 ILE C CD1 1 
ATOM   12438 N N   . PHE C 1 407 ? 152.228 162.439 159.171 1.00 24.51  ? 407 PHE C N   1 
ATOM   12439 C CA  . PHE C 1 407 ? 150.821 162.350 159.553 1.00 19.44  ? 407 PHE C CA  1 
ATOM   12440 C C   . PHE C 1 407 ? 150.552 161.134 160.441 1.00 27.59  ? 407 PHE C C   1 
ATOM   12441 O O   . PHE C 1 407 ? 149.913 161.253 161.478 1.00 33.62  ? 407 PHE C O   1 
ATOM   12442 C CB  . PHE C 1 407 ? 149.949 162.315 158.287 1.00 21.91  ? 407 PHE C CB  1 
ATOM   12443 C CG  . PHE C 1 407 ? 148.590 162.969 158.406 1.00 26.88  ? 407 PHE C CG  1 
ATOM   12444 C CD1 . PHE C 1 407 ? 147.666 162.589 159.395 1.00 30.28  ? 407 PHE C CD1 1 
ATOM   12445 C CD2 . PHE C 1 407 ? 148.252 163.988 157.507 1.00 21.37  ? 407 PHE C CD2 1 
ATOM   12446 C CE1 . PHE C 1 407 ? 146.424 163.231 159.488 1.00 22.49  ? 407 PHE C CE1 1 
ATOM   12447 C CE2 . PHE C 1 407 ? 147.013 164.629 157.599 1.00 27.36  ? 407 PHE C CE2 1 
ATOM   12448 C CZ  . PHE C 1 407 ? 146.102 164.260 158.595 1.00 31.92  ? 407 PHE C CZ  1 
ATOM   12449 N N   . THR C 1 408 ? 151.074 159.969 160.068 1.00 29.24  ? 408 THR C N   1 
ATOM   12450 C CA  . THR C 1 408 ? 150.886 158.711 160.796 1.00 20.34  ? 408 THR C CA  1 
ATOM   12451 C C   . THR C 1 408 ? 151.596 158.711 162.138 1.00 25.95  ? 408 THR C C   1 
ATOM   12452 O O   . THR C 1 408 ? 150.987 158.360 163.142 1.00 41.51  ? 408 THR C O   1 
ATOM   12453 C CB  . THR C 1 408 ? 151.363 157.523 159.960 1.00 21.68  ? 408 THR C CB  1 
ATOM   12454 O OG1 . THR C 1 408 ? 150.728 157.564 158.720 1.00 29.67  ? 408 THR C OG1 1 
ATOM   12455 C CG2 . THR C 1 408 ? 151.026 156.176 160.576 1.00 22.10  ? 408 THR C CG2 1 
ATOM   12456 N N   . VAL C 1 409 ? 152.855 159.146 162.184 1.00 29.71  ? 409 VAL C N   1 
ATOM   12457 C CA  . VAL C 1 409 ? 153.616 159.286 163.427 1.00 28.52  ? 409 VAL C CA  1 
ATOM   12458 C C   . VAL C 1 409 ? 152.920 160.252 164.381 1.00 31.65  ? 409 VAL C C   1 
ATOM   12459 O O   . VAL C 1 409 ? 152.786 159.945 165.556 1.00 44.04  ? 409 VAL C O   1 
ATOM   12460 C CB  . VAL C 1 409 ? 155.063 159.721 163.138 1.00 30.59  ? 409 VAL C CB  1 
ATOM   12461 C CG1 . VAL C 1 409 ? 155.830 160.135 164.393 1.00 34.77  ? 409 VAL C CG1 1 
ATOM   12462 C CG2 . VAL C 1 409 ? 155.830 158.570 162.487 1.00 31.85  ? 409 VAL C CG2 1 
ATOM   12463 N N   . VAL C 1 410 ? 152.384 161.372 163.907 1.00 26.27  ? 410 VAL C N   1 
ATOM   12464 C CA  . VAL C 1 410 ? 151.665 162.343 164.742 1.00 32.22  ? 410 VAL C CA  1 
ATOM   12465 C C   . VAL C 1 410 ? 150.299 161.841 165.197 1.00 33.06  ? 410 VAL C C   1 
ATOM   12466 O O   . VAL C 1 410 ? 149.940 162.020 166.357 1.00 43.98  ? 410 VAL C O   1 
ATOM   12467 C CB  . VAL C 1 410 ? 151.530 163.674 163.991 1.00 34.58  ? 410 VAL C CB  1 
ATOM   12468 C CG1 . VAL C 1 410 ? 150.623 164.697 164.679 1.00 35.90  ? 410 VAL C CG1 1 
ATOM   12469 C CG2 . VAL C 1 410 ? 152.902 164.332 163.837 1.00 30.99  ? 410 VAL C CG2 1 
ATOM   12470 N N   . ALA C 1 411 ? 149.517 161.192 164.335 1.00 38.29  ? 411 ALA C N   1 
ATOM   12471 C CA  . ALA C 1 411 ? 148.218 160.641 164.716 1.00 35.52  ? 411 ALA C CA  1 
ATOM   12472 C C   . ALA C 1 411 ? 148.335 159.507 165.749 1.00 39.06  ? 411 ALA C C   1 
ATOM   12473 O O   . ALA C 1 411 ? 147.529 159.421 166.669 1.00 43.69  ? 411 ALA C O   1 
ATOM   12474 C CB  . ALA C 1 411 ? 147.501 160.180 163.449 1.00 35.36  ? 411 ALA C CB  1 
ATOM   12475 N N   . TYR C 1 412 ? 149.379 158.683 165.659 1.00 40.82  ? 412 TYR C N   1 
ATOM   12476 C CA  . TYR C 1 412 ? 149.648 157.609 166.608 1.00 37.29  ? 412 TYR C CA  1 
ATOM   12477 C C   . TYR C 1 412 ? 150.113 158.104 167.996 1.00 43.20  ? 412 TYR C C   1 
ATOM   12478 O O   . TYR C 1 412 ? 149.949 157.384 168.980 1.00 49.97  ? 412 TYR C O   1 
ATOM   12479 C CB  . TYR C 1 412 ? 150.661 156.661 165.965 1.00 38.24  ? 412 TYR C CB  1 
ATOM   12480 C CG  . TYR C 1 412 ? 150.916 155.386 166.743 1.00 45.39  ? 412 TYR C CG  1 
ATOM   12481 C CD1 . TYR C 1 412 ? 150.077 154.273 166.564 1.00 43.62  ? 412 TYR C CD1 1 
ATOM   12482 C CD2 . TYR C 1 412 ? 152.002 155.304 167.629 1.00 47.21  ? 412 TYR C CD2 1 
ATOM   12483 C CE1 . TYR C 1 412 ? 150.347 153.071 167.246 1.00 44.42  ? 412 TYR C CE1 1 
ATOM   12484 C CE2 . TYR C 1 412 ? 152.271 154.111 168.319 1.00 47.45  ? 412 TYR C CE2 1 
ATOM   12485 C CZ  . TYR C 1 412 ? 151.453 152.984 168.118 1.00 49.03  ? 412 TYR C CZ  1 
ATOM   12486 O OH  . TYR C 1 412 ? 151.720 151.837 168.793 1.00 49.61  ? 412 TYR C OH  1 
ATOM   12487 N N   . HIS C 1 413 ? 150.640 159.326 168.114 1.00 43.23  ? 413 HIS C N   1 
ATOM   12488 C CA  . HIS C 1 413 ? 151.162 159.908 169.360 1.00 42.12  ? 413 HIS C CA  1 
ATOM   12489 C C   . HIS C 1 413 ? 150.312 161.057 169.929 1.00 46.09  ? 413 HIS C C   1 
ATOM   12490 O O   . HIS C 1 413 ? 150.809 161.850 170.726 1.00 54.82  ? 413 HIS C O   1 
ATOM   12491 C CB  . HIS C 1 413 ? 152.640 160.294 169.203 1.00 40.56  ? 413 HIS C CB  1 
ATOM   12492 C CG  . HIS C 1 413 ? 153.559 159.135 168.942 1.00 41.51  ? 413 HIS C CG  1 
ATOM   12493 N ND1 . HIS C 1 413 ? 153.935 158.659 167.715 1.00 45.94  ? 413 HIS C ND1 1 
ATOM   12494 C CD2 . HIS C 1 413 ? 154.169 158.347 169.875 1.00 44.67  ? 413 HIS C CD2 1 
ATOM   12495 C CE1 . HIS C 1 413 ? 154.772 157.631 167.891 1.00 47.38  ? 413 HIS C CE1 1 
ATOM   12496 N NE2 . HIS C 1 413 ? 154.936 157.387 169.201 1.00 45.05  ? 413 HIS C NE2 1 
ATOM   12497 N N   . GLN C 1 414 ? 149.025 161.125 169.599 1.00 44.89  ? 414 GLN C N   1 
ATOM   12498 C CA  . GLN C 1 414 ? 148.101 162.067 170.231 1.00 48.82  ? 414 GLN C CA  1 
ATOM   12499 C C   . GLN C 1 414 ? 147.986 161.815 171.749 1.00 53.51  ? 414 GLN C C   1 
ATOM   12500 O O   . GLN C 1 414 ? 147.828 160.660 172.159 1.00 55.14  ? 414 GLN C O   1 
ATOM   12501 C CB  . GLN C 1 414 ? 146.711 161.955 169.589 1.00 49.37  ? 414 GLN C CB  1 
ATOM   12502 C CG  . GLN C 1 414 ? 146.714 162.367 168.114 1.00 48.87  ? 414 GLN C CG  1 
ATOM   12503 C CD  . GLN C 1 414 ? 147.092 163.821 167.915 1.00 52.71  ? 414 GLN C CD  1 
ATOM   12504 O OE1 . GLN C 1 414 ? 146.476 164.721 168.451 1.00 54.97  ? 414 GLN C OE1 1 
ATOM   12505 N NE2 . GLN C 1 414 ? 148.109 164.105 167.148 1.00 50.97  ? 414 GLN C NE2 1 
ATOM   12506 N N   . PRO C 1 415 ? 148.034 162.859 172.597 1.00 61.82  ? 415 PRO C N   1 
ATOM   12507 C CA  . PRO C 1 415 ? 147.842 162.725 174.038 1.00 61.01  ? 415 PRO C CA  1 
ATOM   12508 C C   . PRO C 1 415 ? 146.371 162.462 174.391 1.00 61.39  ? 415 PRO C C   1 
ATOM   12509 O O   . PRO C 1 415 ? 145.471 162.708 173.588 1.00 61.65  ? 415 PRO C O   1 
ATOM   12510 C CB  . PRO C 1 415 ? 148.343 164.049 174.625 1.00 60.53  ? 415 PRO C CB  1 
ATOM   12511 C CG  . PRO C 1 415 ? 148.018 165.057 173.528 1.00 59.50  ? 415 PRO C CG  1 
ATOM   12512 C CD  . PRO C 1 415 ? 148.252 164.257 172.249 1.00 59.05  ? 415 PRO C CD  1 
ATOM   12513 N N   . SER C 1 416 ? 146.116 162.001 175.616 1.00 66.75  ? 416 SER C N   1 
ATOM   12514 C CA  . SER C 1 416 ? 144.760 161.903 176.168 1.00 68.58  ? 416 SER C CA  1 
ATOM   12515 C C   . SER C 1 416 ? 144.096 163.284 176.272 1.00 70.01  ? 416 SER C C   1 
ATOM   12516 O O   . SER C 1 416 ? 144.763 164.282 176.556 1.00 69.71  ? 416 SER C O   1 
ATOM   12517 C CB  . SER C 1 416 ? 144.810 161.225 177.540 1.00 68.79  ? 416 SER C CB  1 
ATOM   12518 O OG  . SER C 1 416 ? 143.506 161.050 178.059 1.00 69.23  ? 416 SER C OG  1 
ATOM   12519 N N   . LEU C 1 417 ? 142.786 163.362 176.027 1.00 70.25  ? 417 LEU C N   1 
ATOM   12520 C CA  . LEU C 1 417 ? 142.043 164.626 175.988 1.00 71.33  ? 417 LEU C CA  1 
ATOM   12521 C C   . LEU C 1 417 ? 141.714 165.163 177.392 1.00 71.83  ? 417 LEU C C   1 
ATOM   12522 O O   . LEU C 1 417 ? 141.157 164.461 178.242 1.00 69.22  ? 417 LEU C O   1 
ATOM   12523 C CB  . LEU C 1 417 ? 140.785 164.499 175.107 1.00 69.38  ? 417 LEU C CB  1 
ATOM   12524 C CG  . LEU C 1 417 ? 141.026 163.945 173.687 1.00 70.14  ? 417 LEU C CG  1 
ATOM   12525 C CD1 . LEU C 1 417 ? 139.778 164.150 172.832 1.00 71.08  ? 417 LEU C CD1 1 
ATOM   12526 C CD2 . LEU C 1 417 ? 142.181 164.637 172.973 1.00 70.39  ? 417 LEU C CD2 1 
ATOM   12527 N N   . PHE C 1 429 ? 161.095 166.947 175.217 1.00 75.29  ? 429 PHE C N   1 
ATOM   12528 C CA  . PHE C 1 429 ? 161.509 166.979 173.817 1.00 76.49  ? 429 PHE C CA  1 
ATOM   12529 C C   . PHE C 1 429 ? 160.422 166.441 172.879 1.00 76.10  ? 429 PHE C C   1 
ATOM   12530 O O   . PHE C 1 429 ? 160.078 167.097 171.891 1.00 76.57  ? 429 PHE C O   1 
ATOM   12531 C CB  . PHE C 1 429 ? 162.808 166.176 173.662 1.00 75.45  ? 429 PHE C CB  1 
ATOM   12532 C CG  . PHE C 1 429 ? 163.228 165.938 172.223 1.00 75.47  ? 429 PHE C CG  1 
ATOM   12533 C CD1 . PHE C 1 429 ? 163.674 167.013 171.435 1.00 74.70  ? 429 PHE C CD1 1 
ATOM   12534 C CD2 . PHE C 1 429 ? 163.182 164.643 171.671 1.00 76.37  ? 429 PHE C CD2 1 
ATOM   12535 C CE1 . PHE C 1 429 ? 164.097 166.791 170.114 1.00 75.62  ? 429 PHE C CE1 1 
ATOM   12536 C CE2 . PHE C 1 429 ? 163.606 164.422 170.354 1.00 75.86  ? 429 PHE C CE2 1 
ATOM   12537 C CZ  . PHE C 1 429 ? 164.075 165.497 169.578 1.00 75.61  ? 429 PHE C CZ  1 
ATOM   12538 N N   . GLY C 1 430 ? 159.830 165.295 173.210 1.00 75.31  ? 430 GLY C N   1 
ATOM   12539 C CA  . GLY C 1 430 ? 158.803 164.634 172.402 1.00 73.39  ? 430 GLY C CA  1 
ATOM   12540 C C   . GLY C 1 430 ? 157.541 165.480 172.215 1.00 73.23  ? 430 GLY C C   1 
ATOM   12541 O O   . GLY C 1 430 ? 156.948 165.467 171.139 1.00 75.17  ? 430 GLY C O   1 
ATOM   12542 N N   . GLU C 1 431 ? 157.174 166.301 173.198 1.00 70.66  ? 431 GLU C N   1 
ATOM   12543 C CA  . GLU C 1 431 ? 156.079 167.266 173.076 1.00 69.47  ? 431 GLU C CA  1 
ATOM   12544 C C   . GLU C 1 431 ? 156.373 168.382 172.064 1.00 70.48  ? 431 GLU C C   1 
ATOM   12545 O O   . GLU C 1 431 ? 155.473 168.813 171.345 1.00 71.10  ? 431 GLU C O   1 
ATOM   12546 C CB  . GLU C 1 431 ? 155.805 167.861 174.455 1.00 68.59  ? 431 GLU C CB  1 
ATOM   12547 N N   . SER C 1 432 ? 157.633 168.818 171.937 1.00 70.20  ? 432 SER C N   1 
ATOM   12548 C CA  . SER C 1 432 ? 158.041 169.800 170.920 1.00 70.70  ? 432 SER C CA  1 
ATOM   12549 C C   . SER C 1 432 ? 158.066 169.198 169.509 1.00 70.93  ? 432 SER C C   1 
ATOM   12550 O O   . SER C 1 432 ? 157.595 169.816 168.561 1.00 70.10  ? 432 SER C O   1 
ATOM   12551 C CB  . SER C 1 432 ? 159.388 170.440 171.287 1.00 71.11  ? 432 SER C CB  1 
ATOM   12552 O OG  . SER C 1 432 ? 160.502 169.621 170.981 1.00 73.10  ? 432 SER C OG  1 
ATOM   12553 N N   . MET C 1 433 ? 158.522 167.948 169.366 1.00 67.85  ? 433 MET C N   1 
ATOM   12554 C CA  . MET C 1 433 ? 158.451 167.217 168.100 1.00 65.56  ? 433 MET C CA  1 
ATOM   12555 C C   . MET C 1 433 ? 157.011 166.918 167.677 1.00 65.22  ? 433 MET C C   1 
ATOM   12556 O O   . MET C 1 433 ? 156.698 166.976 166.491 1.00 68.18  ? 433 MET C O   1 
ATOM   12557 C CB  . MET C 1 433 ? 159.272 165.923 168.189 1.00 65.66  ? 433 MET C CB  1 
ATOM   12558 C CG  . MET C 1 433 ? 160.765 166.202 168.016 1.00 68.60  ? 433 MET C CG  1 
ATOM   12559 S SD  . MET C 1 433 ? 161.179 166.782 166.349 1.00 78.83  ? 433 MET C SD  1 
ATOM   12560 C CE  . MET C 1 433 ? 162.952 167.074 166.534 1.00 67.37  ? 433 MET C CE  1 
ATOM   12561 N N   . LEU C 1 434 ? 156.103 166.674 168.622 1.00 56.02  ? 434 LEU C N   1 
ATOM   12562 C CA  . LEU C 1 434 ? 154.681 166.536 168.329 1.00 56.03  ? 434 LEU C CA  1 
ATOM   12563 C C   . LEU C 1 434 ? 154.055 167.863 167.863 1.00 58.14  ? 434 LEU C C   1 
ATOM   12564 O O   . LEU C 1 434 ? 153.267 167.857 166.923 1.00 60.37  ? 434 LEU C O   1 
ATOM   12565 C CB  . LEU C 1 434 ? 153.968 165.942 169.556 1.00 57.75  ? 434 LEU C CB  1 
ATOM   12566 C CG  . LEU C 1 434 ? 152.507 165.556 169.283 1.00 57.04  ? 434 LEU C CG  1 
ATOM   12567 C CD1 . LEU C 1 434 ? 152.388 164.376 168.316 1.00 56.19  ? 434 LEU C CD1 1 
ATOM   12568 C CD2 . LEU C 1 434 ? 151.812 165.172 170.578 1.00 56.70  ? 434 LEU C CD2 1 
ATOM   12569 N N   . LEU C 1 435 ? 154.422 169.005 168.455 1.00 57.91  ? 435 LEU C N   1 
ATOM   12570 C CA  . LEU C 1 435 ? 154.013 170.333 167.973 1.00 59.40  ? 435 LEU C CA  1 
ATOM   12571 C C   . LEU C 1 435 ? 154.536 170.620 166.555 1.00 58.86  ? 435 LEU C C   1 
ATOM   12572 O O   . LEU C 1 435 ? 153.771 171.059 165.699 1.00 56.11  ? 435 LEU C O   1 
ATOM   12573 C CB  . LEU C 1 435 ? 154.483 171.398 168.977 1.00 61.73  ? 435 LEU C CB  1 
ATOM   12574 C CG  . LEU C 1 435 ? 154.202 172.853 168.563 1.00 60.67  ? 435 LEU C CG  1 
ATOM   12575 C CD1 . LEU C 1 435 ? 152.707 173.155 168.529 1.00 57.75  ? 435 LEU C CD1 1 
ATOM   12576 C CD2 . LEU C 1 435 ? 154.873 173.804 169.546 1.00 60.66  ? 435 LEU C CD2 1 
ATOM   12577 N N   . LEU C 1 436 ? 155.811 170.319 166.285 1.00 52.84  ? 436 LEU C N   1 
ATOM   12578 C CA  . LEU C 1 436 ? 156.394 170.436 164.948 1.00 50.75  ? 436 LEU C CA  1 
ATOM   12579 C C   . LEU C 1 436 ? 155.618 169.580 163.934 1.00 53.43  ? 436 LEU C C   1 
ATOM   12580 O O   . LEU C 1 436 ? 155.241 170.062 162.871 1.00 54.14  ? 436 LEU C O   1 
ATOM   12581 C CB  . LEU C 1 436 ? 157.886 170.056 164.997 1.00 50.72  ? 436 LEU C CB  1 
ATOM   12582 C CG  . LEU C 1 436 ? 158.580 170.089 163.623 1.00 51.81  ? 436 LEU C CG  1 
ATOM   12583 C CD1 . LEU C 1 436 ? 158.595 171.494 163.022 1.00 53.49  ? 436 LEU C CD1 1 
ATOM   12584 C CD2 . LEU C 1 436 ? 160.021 169.608 163.748 1.00 49.99  ? 436 LEU C CD2 1 
ATOM   12585 N N   . GLY C 1 437 ? 155.305 168.335 164.286 1.00 46.77  ? 437 GLY C N   1 
ATOM   12586 C CA  . GLY C 1 437 ? 154.485 167.455 163.465 1.00 41.77  ? 437 GLY C CA  1 
ATOM   12587 C C   . GLY C 1 437 ? 153.093 168.010 163.157 1.00 42.20  ? 437 GLY C C   1 
ATOM   12588 O O   . GLY C 1 437 ? 152.644 167.917 162.020 1.00 49.59  ? 437 GLY C O   1 
ATOM   12589 N N   . HIS C 1 438 ? 152.415 168.650 164.110 1.00 40.39  ? 438 HIS C N   1 
ATOM   12590 C CA  . HIS C 1 438 ? 151.122 169.292 163.844 1.00 43.77  ? 438 HIS C CA  1 
ATOM   12591 C C   . HIS C 1 438 ? 151.216 170.481 162.884 1.00 47.43  ? 438 HIS C C   1 
ATOM   12592 O O   . HIS C 1 438 ? 150.373 170.603 161.999 1.00 49.93  ? 438 HIS C O   1 
ATOM   12593 C CB  . HIS C 1 438 ? 150.441 169.732 165.142 1.00 48.39  ? 438 HIS C CB  1 
ATOM   12594 C CG  . HIS C 1 438 ? 149.861 168.595 165.932 1.00 48.02  ? 438 HIS C CG  1 
ATOM   12595 N ND1 . HIS C 1 438 ? 150.488 167.883 166.917 1.00 49.15  ? 438 HIS C ND1 1 
ATOM   12596 C CD2 . HIS C 1 438 ? 148.630 168.033 165.757 1.00 46.70  ? 438 HIS C CD2 1 
ATOM   12597 C CE1 . HIS C 1 438 ? 149.652 166.934 167.352 1.00 49.90  ? 438 HIS C CE1 1 
ATOM   12598 N NE2 . HIS C 1 438 ? 148.501 166.984 166.667 1.00 50.94  ? 438 HIS C NE2 1 
ATOM   12599 N N   . ILE C 1 439 ? 152.227 171.345 162.998 1.00 47.25  ? 439 ILE C N   1 
ATOM   12600 C CA  . ILE C 1 439 ? 152.370 172.465 162.057 1.00 45.54  ? 439 ILE C CA  1 
ATOM   12601 C C   . ILE C 1 439 ? 152.860 172.000 160.678 1.00 44.21  ? 439 ILE C C   1 
ATOM   12602 O O   . ILE C 1 439 ? 152.408 172.548 159.680 1.00 44.65  ? 439 ILE C O   1 
ATOM   12603 C CB  . ILE C 1 439 ? 153.179 173.644 162.634 1.00 49.87  ? 439 ILE C CB  1 
ATOM   12604 C CG1 . ILE C 1 439 ? 154.649 173.296 162.908 1.00 49.05  ? 439 ILE C CG1 1 
ATOM   12605 C CG2 . ILE C 1 439 ? 152.468 174.183 163.884 1.00 46.25  ? 439 ILE C CG2 1 
ATOM   12606 C CD1 . ILE C 1 439 ? 155.484 174.450 163.452 1.00 49.34  ? 439 ILE C CD1 1 
ATOM   12607 N N   . LEU C 1 440 ? 153.678 170.946 160.570 1.00 38.85  ? 440 LEU C N   1 
ATOM   12608 C CA  . LEU C 1 440 ? 153.981 170.314 159.281 1.00 37.92  ? 440 LEU C CA  1 
ATOM   12609 C C   . LEU C 1 440 ? 152.732 169.707 158.624 1.00 34.57  ? 440 LEU C C   1 
ATOM   12610 O O   . LEU C 1 440 ? 152.552 169.852 157.421 1.00 45.17  ? 440 LEU C O   1 
ATOM   12611 C CB  . LEU C 1 440 ? 155.092 169.262 159.449 1.00 41.19  ? 440 LEU C CB  1 
ATOM   12612 C CG  . LEU C 1 440 ? 156.476 169.838 159.803 1.00 40.88  ? 440 LEU C CG  1 
ATOM   12613 C CD1 . LEU C 1 440 ? 157.451 168.697 160.052 1.00 36.05  ? 440 LEU C CD1 1 
ATOM   12614 C CD2 . LEU C 1 440 ? 157.060 170.710 158.701 1.00 41.82  ? 440 LEU C CD2 1 
ATOM   12615 N N   . ILE C 1 441 ? 151.832 169.084 159.388 1.00 33.24  ? 441 ILE C N   1 
ATOM   12616 C CA  . ILE C 1 441 ? 150.537 168.589 158.888 1.00 35.26  ? 441 ILE C CA  1 
ATOM   12617 C C   . ILE C 1 441 ? 149.615 169.737 158.475 1.00 35.49  ? 441 ILE C C   1 
ATOM   12618 O O   . ILE C 1 441 ? 148.982 169.656 157.429 1.00 42.52  ? 441 ILE C O   1 
ATOM   12619 C CB  . ILE C 1 441 ? 149.876 167.681 159.946 1.00 40.87  ? 441 ILE C CB  1 
ATOM   12620 C CG1 . ILE C 1 441 ? 150.619 166.340 159.953 1.00 33.92  ? 441 ILE C CG1 1 
ATOM   12621 C CG2 . ILE C 1 441 ? 148.378 167.427 159.722 1.00 39.97  ? 441 ILE C CG2 1 
ATOM   12622 C CD1 . ILE C 1 441 ? 150.350 165.566 161.231 1.00 41.73  ? 441 ILE C CD1 1 
ATOM   12623 N N   . LEU C 1 442 ? 149.563 170.826 159.242 1.00 33.96  ? 442 LEU C N   1 
ATOM   12624 C CA  . LEU C 1 442 ? 148.818 172.029 158.870 1.00 34.35  ? 442 LEU C CA  1 
ATOM   12625 C C   . LEU C 1 442 ? 149.333 172.640 157.558 1.00 36.95  ? 442 LEU C C   1 
ATOM   12626 O O   . LEU C 1 442 ? 148.550 172.885 156.649 1.00 41.91  ? 442 LEU C O   1 
ATOM   12627 C CB  . LEU C 1 442 ? 148.876 173.038 160.027 1.00 36.29  ? 442 LEU C CB  1 
ATOM   12628 C CG  . LEU C 1 442 ? 148.156 174.366 159.755 1.00 36.85  ? 442 LEU C CG  1 
ATOM   12629 C CD1 . LEU C 1 442 ? 146.680 174.186 159.425 1.00 35.73  ? 442 LEU C CD1 1 
ATOM   12630 C CD2 . LEU C 1 442 ? 148.260 175.249 160.988 1.00 36.20  ? 442 LEU C CD2 1 
ATOM   12631 N N   . LEU C 1 443 ? 150.642 172.849 157.428 1.00 38.27  ? 443 LEU C N   1 
ATOM   12632 C CA  . LEU C 1 443 ? 151.260 173.423 156.232 1.00 36.53  ? 443 LEU C CA  1 
ATOM   12633 C C   . LEU C 1 443 ? 151.127 172.510 155.013 1.00 33.14  ? 443 LEU C C   1 
ATOM   12634 O O   . LEU C 1 443 ? 150.767 172.992 153.944 1.00 42.78  ? 443 LEU C O   1 
ATOM   12635 C CB  . LEU C 1 443 ? 152.738 173.738 156.508 1.00 38.93  ? 443 LEU C CB  1 
ATOM   12636 C CG  . LEU C 1 443 ? 152.962 174.896 157.492 1.00 39.46  ? 443 LEU C CG  1 
ATOM   12637 C CD1 . LEU C 1 443 ? 154.441 174.954 157.853 1.00 37.38  ? 443 LEU C CD1 1 
ATOM   12638 C CD2 . LEU C 1 443 ? 152.557 176.246 156.903 1.00 37.28  ? 443 LEU C CD2 1 
ATOM   12639 N N   . GLY C 1 444 ? 151.338 171.200 155.161 1.00 27.99  ? 444 GLY C N   1 
ATOM   12640 C CA  . GLY C 1 444 ? 151.082 170.224 154.104 1.00 21.98  ? 444 GLY C CA  1 
ATOM   12641 C C   . GLY C 1 444 ? 149.614 170.168 153.690 1.00 23.34  ? 444 GLY C C   1 
ATOM   12642 O O   . GLY C 1 444 ? 149.314 170.127 152.504 1.00 36.02  ? 444 GLY C O   1 
ATOM   12643 N N   . GLY C 1 445 ? 148.690 170.272 154.641 1.00 29.28  ? 445 GLY C N   1 
ATOM   12644 C CA  . GLY C 1 445 ? 147.262 170.391 154.376 1.00 29.43  ? 445 GLY C CA  1 
ATOM   12645 C C   . GLY C 1 445 ? 146.893 171.667 153.627 1.00 28.20  ? 445 GLY C C   1 
ATOM   12646 O O   . GLY C 1 445 ? 146.161 171.594 152.650 1.00 36.99  ? 445 GLY C O   1 
ATOM   12647 N N   . ILE C 1 446 ? 147.428 172.826 154.016 1.00 33.74  ? 446 ILE C N   1 
ATOM   12648 C CA  . ILE C 1 446 ? 147.231 174.094 153.298 1.00 33.25  ? 446 ILE C CA  1 
ATOM   12649 C C   . ILE C 1 446 ? 147.829 174.018 151.890 1.00 33.32  ? 446 ILE C C   1 
ATOM   12650 O O   . ILE C 1 446 ? 147.163 174.376 150.927 1.00 35.91  ? 446 ILE C O   1 
ATOM   12651 C CB  . ILE C 1 446 ? 147.809 175.282 154.103 1.00 34.57  ? 446 ILE C CB  1 
ATOM   12652 C CG1 . ILE C 1 446 ? 146.965 175.536 155.368 1.00 30.51  ? 446 ILE C CG1 1 
ATOM   12653 C CG2 . ILE C 1 446 ? 147.863 176.570 153.262 1.00 30.88  ? 446 ILE C CG2 1 
ATOM   12654 C CD1 . ILE C 1 446 ? 147.694 176.383 156.416 1.00 31.51  ? 446 ILE C CD1 1 
ATOM   12655 N N   . TYR C 1 447 ? 149.049 173.511 151.738 1.00 26.21  ? 447 TYR C N   1 
ATOM   12656 C CA  . TYR C 1 447 ? 149.702 173.362 150.444 1.00 23.97  ? 447 TYR C CA  1 
ATOM   12657 C C   . TYR C 1 447 ? 148.906 172.478 149.479 1.00 32.00  ? 447 TYR C C   1 
ATOM   12658 O O   . TYR C 1 447 ? 148.667 172.867 148.338 1.00 47.99  ? 447 TYR C O   1 
ATOM   12659 C CB  . TYR C 1 447 ? 151.095 172.780 150.665 1.00 27.58  ? 447 TYR C CB  1 
ATOM   12660 C CG  . TYR C 1 447 ? 151.873 172.590 149.385 1.00 39.32  ? 447 TYR C CG  1 
ATOM   12661 C CD1 . TYR C 1 447 ? 152.662 173.644 148.905 1.00 32.78  ? 447 TYR C CD1 1 
ATOM   12662 C CD2 . TYR C 1 447 ? 151.784 171.387 148.655 1.00 35.10  ? 447 TYR C CD2 1 
ATOM   12663 C CE1 . TYR C 1 447 ? 153.377 173.497 147.713 1.00 34.84  ? 447 TYR C CE1 1 
ATOM   12664 C CE2 . TYR C 1 447 ? 152.493 171.241 147.449 1.00 34.28  ? 447 TYR C CE2 1 
ATOM   12665 C CZ  . TYR C 1 447 ? 153.290 172.300 146.978 1.00 38.42  ? 447 TYR C CZ  1 
ATOM   12666 O OH  . TYR C 1 447 ? 153.958 172.189 145.807 1.00 40.61  ? 447 TYR C OH  1 
ATOM   12667 N N   . LEU C 1 448 ? 148.458 171.309 149.932 1.00 18.73  ? 448 LEU C N   1 
ATOM   12668 C CA  . LEU C 1 448 ? 147.627 170.415 149.135 1.00 19.00  ? 448 LEU C CA  1 
ATOM   12669 C C   . LEU C 1 448 ? 146.267 171.038 148.824 1.00 24.44  ? 448 LEU C C   1 
ATOM   12670 O O   . LEU C 1 448 ? 145.793 170.920 147.699 1.00 31.24  ? 448 LEU C O   1 
ATOM   12671 C CB  . LEU C 1 448 ? 147.470 169.078 149.867 1.00 23.73  ? 448 LEU C CB  1 
ATOM   12672 C CG  . LEU C 1 448 ? 148.761 168.251 149.914 1.00 30.49  ? 448 LEU C CG  1 
ATOM   12673 C CD1 . LEU C 1 448 ? 148.621 167.168 150.971 1.00 27.41  ? 448 LEU C CD1 1 
ATOM   12674 C CD2 . LEU C 1 448 ? 149.069 167.585 148.577 1.00 31.78  ? 448 LEU C CD2 1 
ATOM   12675 N N   . LEU C 1 449 ? 145.658 171.750 149.771 1.00 28.61  ? 449 LEU C N   1 
ATOM   12676 C CA  . LEU C 1 449 ? 144.398 172.459 149.581 1.00 29.67  ? 449 LEU C CA  1 
ATOM   12677 C C   . LEU C 1 449 ? 144.531 173.540 148.501 1.00 27.67  ? 449 LEU C C   1 
ATOM   12678 O O   . LEU C 1 449 ? 143.748 173.549 147.562 1.00 33.28  ? 449 LEU C O   1 
ATOM   12679 C CB  . LEU C 1 449 ? 143.935 173.025 150.936 1.00 33.70  ? 449 LEU C CB  1 
ATOM   12680 C CG  . LEU C 1 449 ? 142.628 173.817 150.918 1.00 31.24  ? 449 LEU C CG  1 
ATOM   12681 C CD1 . LEU C 1 449 ? 141.475 172.967 150.412 1.00 28.21  ? 449 LEU C CD1 1 
ATOM   12682 C CD2 . LEU C 1 449 ? 142.305 174.283 152.331 1.00 29.05  ? 449 LEU C CD2 1 
ATOM   12683 N N   . LEU C 1 450 ? 145.553 174.395 148.570 1.00 32.41  ? 450 LEU C N   1 
ATOM   12684 C CA  . LEU C 1 450 ? 145.818 175.422 147.559 1.00 30.01  ? 450 LEU C CA  1 
ATOM   12685 C C   . LEU C 1 450 ? 146.101 174.811 146.188 1.00 28.05  ? 450 LEU C C   1 
ATOM   12686 O O   . LEU C 1 450 ? 145.522 175.250 145.199 1.00 41.04  ? 450 LEU C O   1 
ATOM   12687 C CB  . LEU C 1 450 ? 146.988 176.312 148.004 1.00 29.88  ? 450 LEU C CB  1 
ATOM   12688 C CG  . LEU C 1 450 ? 146.671 177.204 149.213 1.00 31.33  ? 450 LEU C CG  1 
ATOM   12689 C CD1 . LEU C 1 450 ? 147.947 177.886 149.686 1.00 30.20  ? 450 LEU C CD1 1 
ATOM   12690 C CD2 . LEU C 1 450 ? 145.648 178.284 148.886 1.00 29.99  ? 450 LEU C CD2 1 
ATOM   12691 N N   . GLY C 1 451 ? 146.920 173.763 146.119 1.00 26.14  ? 451 GLY C N   1 
ATOM   12692 C CA  . GLY C 1 451 ? 147.203 173.068 144.869 1.00 19.13  ? 451 GLY C CA  1 
ATOM   12693 C C   . GLY C 1 451 ? 145.969 172.443 144.220 1.00 23.95  ? 451 GLY C C   1 
ATOM   12694 O O   . GLY C 1 451 ? 145.838 172.457 143.000 1.00 37.48  ? 451 GLY C O   1 
ATOM   12695 N N   . GLN C 1 452 ? 145.040 171.963 145.050 1.00 27.07  ? 452 GLN C N   1 
ATOM   12696 C CA  . GLN C 1 452 ? 143.817 171.297 144.519 1.00 25.63  ? 452 GLN C CA  1 
ATOM   12697 C C   . GLN C 1 452 ? 142.785 172.368 144.130 1.00 27.30  ? 452 GLN C C   1 
ATOM   12698 O O   . GLN C 1 452 ? 142.200 172.231 143.037 1.00 39.57  ? 452 GLN C O   1 
ATOM   12699 C CB  . GLN C 1 452 ? 143.374 170.224 145.521 1.00 30.95  ? 452 GLN C CB  1 
ATOM   12700 C CG  . GLN C 1 452 ? 144.360 169.047 145.546 1.00 27.79  ? 452 GLN C CG  1 
ATOM   12701 C CD  . GLN C 1 452 ? 144.202 168.148 144.344 1.00 28.95  ? 452 GLN C CD  1 
ATOM   12702 O OE1 . GLN C 1 452 ? 143.246 168.263 143.579 1.00 36.07  ? 452 GLN C OE1 1 
ATOM   12703 N NE2 . GLN C 1 452 ? 145.142 167.234 144.173 1.00 39.24  ? 452 GLN C NE2 1 
ATOM   12704 N N   . LEU C 1 453 ? 142.569 173.391 144.965 1.00 32.99  ? 453 LEU C N   1 
ATOM   12705 C CA  . LEU C 1 453 ? 141.695 174.501 144.581 1.00 31.52  ? 453 LEU C CA  1 
ATOM   12706 C C   . LEU C 1 453 ? 142.165 175.141 143.271 1.00 29.21  ? 453 LEU C C   1 
ATOM   12707 O O   . LEU C 1 453 ? 141.349 175.462 142.415 1.00 37.05  ? 453 LEU C O   1 
ATOM   12708 C CB  . LEU C 1 453 ? 141.634 175.544 145.710 1.00 32.78  ? 453 LEU C CB  1 
ATOM   12709 C CG  . LEU C 1 453 ? 140.925 175.068 146.984 1.00 32.27  ? 453 LEU C CG  1 
ATOM   12710 C CD1 . LEU C 1 453 ? 141.100 176.118 148.074 1.00 32.35  ? 453 LEU C CD1 1 
ATOM   12711 C CD2 . LEU C 1 453 ? 139.433 174.837 146.769 1.00 29.54  ? 453 LEU C CD2 1 
ATOM   12712 N N   . TRP C 1 454 ? 143.479 175.266 143.074 1.00 30.12  ? 454 TRP C N   1 
ATOM   12713 C CA  . TRP C 1 454 ? 144.069 175.719 141.819 1.00 29.15  ? 454 TRP C CA  1 
ATOM   12714 C C   . TRP C 1 454 ? 143.807 174.762 140.648 1.00 29.78  ? 454 TRP C C   1 
ATOM   12715 O O   . TRP C 1 454 ? 143.472 175.226 139.563 1.00 41.71  ? 454 TRP C O   1 
ATOM   12716 C CB  . TRP C 1 454 ? 145.563 175.964 142.030 1.00 29.99  ? 454 TRP C CB  1 
ATOM   12717 C CG  . TRP C 1 454 ? 146.317 176.458 140.837 1.00 39.68  ? 454 TRP C CG  1 
ATOM   12718 C CD1 . TRP C 1 454 ? 146.104 177.639 140.213 1.00 38.20  ? 454 TRP C CD1 1 
ATOM   12719 C CD2 . TRP C 1 454 ? 147.408 175.820 140.109 1.00 38.97  ? 454 TRP C CD2 1 
ATOM   12720 N NE1 . TRP C 1 454 ? 146.999 177.782 139.174 1.00 33.21  ? 454 TRP C NE1 1 
ATOM   12721 C CE2 . TRP C 1 454 ? 147.845 176.704 139.084 1.00 37.17  ? 454 TRP C CE2 1 
ATOM   12722 C CE3 . TRP C 1 454 ? 148.077 174.580 140.215 1.00 34.63  ? 454 TRP C CE3 1 
ATOM   12723 C CZ2 . TRP C 1 454 ? 148.899 176.386 138.218 1.00 40.94  ? 454 TRP C CZ2 1 
ATOM   12724 C CZ3 . TRP C 1 454 ? 149.150 174.261 139.363 1.00 41.27  ? 454 TRP C CZ3 1 
ATOM   12725 C CH2 . TRP C 1 454 ? 149.567 175.161 138.368 1.00 38.92  ? 454 TRP C CH2 1 
ATOM   12726 N N   . TYR C 1 455 ? 143.856 173.443 140.851 1.00 35.86  ? 455 TYR C N   1 
ATOM   12727 C CA  . TYR C 1 455 ? 143.438 172.469 139.840 1.00 32.60  ? 455 TYR C CA  1 
ATOM   12728 C C   . TYR C 1 455 ? 141.988 172.696 139.405 1.00 32.49  ? 455 TYR C C   1 
ATOM   12729 O O   . TYR C 1 455 ? 141.719 172.887 138.221 1.00 40.82  ? 455 TYR C O   1 
ATOM   12730 C CB  . TYR C 1 455 ? 143.630 171.031 140.344 1.00 34.39  ? 455 TYR C CB  1 
ATOM   12731 C CG  . TYR C 1 455 ? 143.126 169.976 139.376 1.00 36.31  ? 455 TYR C CG  1 
ATOM   12732 C CD1 . TYR C 1 455 ? 143.962 169.516 138.344 1.00 33.92  ? 455 TYR C CD1 1 
ATOM   12733 C CD2 . TYR C 1 455 ? 141.808 169.488 139.469 1.00 33.24  ? 455 TYR C CD2 1 
ATOM   12734 C CE1 . TYR C 1 455 ? 143.491 168.578 137.412 1.00 33.68  ? 455 TYR C CE1 1 
ATOM   12735 C CE2 . TYR C 1 455 ? 141.322 168.565 138.527 1.00 37.03  ? 455 TYR C CE2 1 
ATOM   12736 C CZ  . TYR C 1 455 ? 142.171 168.096 137.501 1.00 40.58  ? 455 TYR C CZ  1 
ATOM   12737 O OH  . TYR C 1 455 ? 141.735 167.170 136.607 1.00 41.54  ? 455 TYR C OH  1 
ATOM   12738 N N   . PHE C 1 456 ? 141.045 172.738 140.346 1.00 33.35  ? 456 PHE C N   1 
ATOM   12739 C CA  . PHE C 1 456 ? 139.639 172.942 140.009 1.00 31.80  ? 456 PHE C CA  1 
ATOM   12740 C C   . PHE C 1 456 ? 139.340 174.331 139.445 1.00 37.82  ? 456 PHE C C   1 
ATOM   12741 O O   . PHE C 1 456 ? 138.448 174.448 138.613 1.00 44.84  ? 456 PHE C O   1 
ATOM   12742 C CB  . PHE C 1 456 ? 138.752 172.599 141.204 1.00 33.13  ? 456 PHE C CB  1 
ATOM   12743 C CG  . PHE C 1 456 ? 138.674 171.110 141.460 1.00 37.52  ? 456 PHE C CG  1 
ATOM   12744 C CD1 . PHE C 1 456 ? 138.150 170.262 140.468 1.00 39.77  ? 456 PHE C CD1 1 
ATOM   12745 C CD2 . PHE C 1 456 ? 139.147 170.565 142.664 1.00 34.64  ? 456 PHE C CD2 1 
ATOM   12746 C CE1 . PHE C 1 456 ? 138.103 168.876 140.674 1.00 38.82  ? 456 PHE C CE1 1 
ATOM   12747 C CE2 . PHE C 1 456 ? 139.096 169.178 142.872 1.00 32.52  ? 456 PHE C CE2 1 
ATOM   12748 C CZ  . PHE C 1 456 ? 138.573 168.336 141.879 1.00 36.83  ? 456 PHE C CZ  1 
ATOM   12749 N N   . TRP C 1 457 ? 140.102 175.367 139.797 1.00 39.02  ? 457 TRP C N   1 
ATOM   12750 C CA  . TRP C 1 457 ? 140.025 176.663 139.127 1.00 38.16  ? 457 TRP C CA  1 
ATOM   12751 C C   . TRP C 1 457 ? 140.483 176.595 137.667 1.00 43.87  ? 457 TRP C C   1 
ATOM   12752 O O   . TRP C 1 457 ? 139.762 177.026 136.768 1.00 48.05  ? 457 TRP C O   1 
ATOM   12753 C CB  . TRP C 1 457 ? 140.826 177.711 139.895 1.00 44.26  ? 457 TRP C CB  1 
ATOM   12754 C CG  . TRP C 1 457 ? 140.712 179.077 139.300 1.00 48.56  ? 457 TRP C CG  1 
ATOM   12755 C CD1 . TRP C 1 457 ? 141.699 179.757 138.678 1.00 47.80  ? 457 TRP C CD1 1 
ATOM   12756 C CD2 . TRP C 1 457 ? 139.532 179.933 139.244 1.00 45.67  ? 457 TRP C CD2 1 
ATOM   12757 N NE1 . TRP C 1 457 ? 141.212 180.971 138.243 1.00 48.59  ? 457 TRP C NE1 1 
ATOM   12758 C CE2 . TRP C 1 457 ? 139.879 181.133 138.558 1.00 46.65  ? 457 TRP C CE2 1 
ATOM   12759 C CE3 . TRP C 1 457 ? 138.202 179.813 139.698 1.00 45.69  ? 457 TRP C CE3 1 
ATOM   12760 C CZ2 . TRP C 1 457 ? 138.956 182.159 138.338 1.00 46.50  ? 457 TRP C CZ2 1 
ATOM   12761 C CZ3 . TRP C 1 457 ? 137.263 180.838 139.474 1.00 46.27  ? 457 TRP C CZ3 1 
ATOM   12762 C CH2 . TRP C 1 457 ? 137.639 182.007 138.795 1.00 46.80  ? 457 TRP C CH2 1 
ATOM   12763 N N   . ARG C 1 458 ? 141.641 175.982 137.403 1.00 38.90  ? 458 ARG C N   1 
ATOM   12764 C CA  . ARG C 1 458 ? 142.133 175.844 136.000 1.00 37.22  ? 458 ARG C CA  1 
ATOM   12765 C C   . ARG C 1 458 ? 141.153 175.014 135.165 1.00 40.39  ? 458 ARG C C   1 
ATOM   12766 O O   . ARG C 1 458 ? 140.946 175.365 133.987 1.00 48.20  ? 458 ARG C O   1 
ATOM   12767 C CB  . ARG C 1 458 ? 143.534 175.236 135.997 1.00 37.89  ? 458 ARG C CB  1 
ATOM   12768 C CG  . ARG C 1 458 ? 144.593 176.265 136.389 1.00 33.03  ? 458 ARG C CG  1 
ATOM   12769 C CD  . ARG C 1 458 ? 145.993 175.698 136.147 1.00 35.18  ? 458 ARG C CD  1 
ATOM   12770 N NE  . ARG C 1 458 ? 146.322 174.674 137.129 1.00 36.16  ? 458 ARG C NE  1 
ATOM   12771 C CZ  . ARG C 1 458 ? 146.005 173.389 137.018 1.00 40.16  ? 458 ARG C CZ  1 
ATOM   12772 N NH1 . ARG C 1 458 ? 146.350 172.538 137.968 1.00 40.88  ? 458 ARG C NH1 1 
ATOM   12773 N NH2 . ARG C 1 458 ? 145.340 172.959 135.960 1.00 40.85  ? 458 ARG C NH2 1 
ATOM   12774 N N   . ARG C 1 459 ? 140.556 173.986 135.788 1.00 39.12  ? 459 ARG C N   1 
ATOM   12775 C CA  . ARG C 1 459 ? 139.629 173.058 135.086 1.00 40.05  ? 459 ARG C CA  1 
ATOM   12776 C C   . ARG C 1 459 ? 138.158 173.420 135.381 1.00 46.58  ? 459 ARG C C   1 
ATOM   12777 O O   . ARG C 1 459 ? 137.325 172.493 135.344 1.00 50.00  ? 459 ARG C O   1 
ATOM   12778 C CB  . ARG C 1 459 ? 139.902 171.612 135.554 1.00 35.85  ? 459 ARG C CB  1 
ATOM   12779 C CG  . ARG C 1 459 ? 141.356 171.129 135.354 1.00 36.77  ? 459 ARG C CG  1 
ATOM   12780 C CD  . ARG C 1 459 ? 141.810 171.158 133.892 1.00 38.05  ? 459 ARG C CD  1 
ATOM   12781 N NE  . ARG C 1 459 ? 143.246 170.952 133.764 1.00 37.44  ? 459 ARG C NE  1 
ATOM   12782 C CZ  . ARG C 1 459 ? 143.934 171.123 132.641 1.00 43.68  ? 459 ARG C CZ  1 
ATOM   12783 N NH1 . ARG C 1 459 ? 145.239 170.912 132.626 1.00 43.29  ? 459 ARG C NH1 1 
ATOM   12784 N NH2 . ARG C 1 459 ? 143.317 171.511 131.541 1.00 41.17  ? 459 ARG C NH2 1 
ATOM   12785 N N   . ARG C 1 460 ? 137.839 174.712 135.590 1.00 52.55  ? 460 ARG C N   1 
ATOM   12786 C CA  . ARG C 1 460 ? 136.455 175.144 135.986 1.00 50.21  ? 460 ARG C CA  1 
ATOM   12787 C C   . ARG C 1 460 ? 135.468 175.064 134.812 1.00 53.20  ? 460 ARG C C   1 
ATOM   12788 O O   . ARG C 1 460 ? 134.299 174.714 135.061 1.00 53.61  ? 460 ARG C O   1 
ATOM   12789 C CB  . ARG C 1 460 ? 136.469 176.532 136.650 1.00 49.37  ? 460 ARG C CB  1 
ATOM   12790 C CG  . ARG C 1 460 ? 136.826 177.680 135.698 1.00 47.51  ? 460 ARG C CG  1 
ATOM   12791 C CD  . ARG C 1 460 ? 137.120 178.958 136.479 1.00 49.21  ? 460 ARG C CD  1 
ATOM   12792 N NE  . ARG C 1 460 ? 137.633 180.035 135.646 1.00 52.75  ? 460 ARG C NE  1 
ATOM   12793 C CZ  . ARG C 1 460 ? 138.921 180.254 135.406 1.00 54.17  ? 460 ARG C CZ  1 
ATOM   12794 N NH1 . ARG C 1 460 ? 139.289 181.263 134.635 1.00 51.21  ? 460 ARG C NH1 1 
ATOM   12795 N NH2 . ARG C 1 460 ? 139.837 179.464 135.938 1.00 54.53  ? 460 ARG C NH2 1 
ATOM   12796 N N   . LEU C 1 461 ? 135.914 175.364 133.595 1.00 52.83  ? 461 LEU C N   1 
ATOM   12797 C CA  . LEU C 1 461 ? 135.066 175.363 132.391 1.00 52.06  ? 461 LEU C CA  1 
ATOM   12798 C C   . LEU C 1 461 ? 134.554 173.961 132.013 1.00 52.62  ? 461 LEU C C   1 
ATOM   12799 O O   . LEU C 1 461 ? 133.548 173.833 131.320 1.00 54.38  ? 461 LEU C O   1 
ATOM   12800 C CB  . LEU C 1 461 ? 135.835 175.989 131.212 1.00 55.68  ? 461 LEU C CB  1 
ATOM   12801 C CG  . LEU C 1 461 ? 136.320 177.437 131.420 1.00 56.25  ? 461 LEU C CG  1 
ATOM   12802 C CD1 . LEU C 1 461 ? 137.120 177.894 130.208 1.00 51.91  ? 461 LEU C CD1 1 
ATOM   12803 C CD2 . LEU C 1 461 ? 135.167 178.409 131.617 1.00 53.10  ? 461 LEU C CD2 1 
ATOM   12804 N N   . PHE C 1 462 ? 135.227 172.912 132.493 1.00 50.24  ? 462 PHE C N   1 
ATOM   12805 C CA  . PHE C 1 462 ? 134.916 171.500 132.244 1.00 51.06  ? 462 PHE C CA  1 
ATOM   12806 C C   . PHE C 1 462 ? 134.864 170.704 133.558 1.00 49.29  ? 462 PHE C C   1 
ATOM   12807 O O   . PHE C 1 462 ? 135.216 169.524 133.619 1.00 51.17  ? 462 PHE C O   1 
ATOM   12808 C CB  . PHE C 1 462 ? 135.913 170.927 131.219 1.00 49.11  ? 462 PHE C CB  1 
ATOM   12809 C CG  . PHE C 1 462 ? 135.807 171.568 129.851 1.00 46.83  ? 462 PHE C CG  1 
ATOM   12810 C CD1 . PHE C 1 462 ? 134.891 171.068 128.911 1.00 47.83  ? 462 PHE C CD1 1 
ATOM   12811 C CD2 . PHE C 1 462 ? 136.597 172.686 129.527 1.00 48.81  ? 462 PHE C CD2 1 
ATOM   12812 C CE1 . PHE C 1 462 ? 134.754 171.688 127.656 1.00 49.97  ? 462 PHE C CE1 1 
ATOM   12813 C CE2 . PHE C 1 462 ? 136.457 173.309 128.276 1.00 52.02  ? 462 PHE C CE2 1 
ATOM   12814 C CZ  . PHE C 1 462 ? 135.540 172.810 127.341 1.00 49.41  ? 462 PHE C CZ  1 
ATOM   12815 N N   . ILE C 1 463 ? 134.455 171.348 134.653 1.00 51.99  ? 463 ILE C N   1 
ATOM   12816 C CA  . ILE C 1 463 ? 134.661 170.803 135.996 1.00 56.47  ? 463 ILE C CA  1 
ATOM   12817 C C   . ILE C 1 463 ? 133.950 169.461 136.210 1.00 54.74  ? 463 ILE C C   1 
ATOM   12818 O O   . ILE C 1 463 ? 134.575 168.539 136.723 1.00 54.98  ? 463 ILE C O   1 
ATOM   12819 C CB  . ILE C 1 463 ? 134.334 171.860 137.069 1.00 54.84  ? 463 ILE C CB  1 
ATOM   12820 C CG1 . ILE C 1 463 ? 134.901 171.414 138.430 1.00 53.67  ? 463 ILE C CG1 1 
ATOM   12821 C CG2 . ILE C 1 463 ? 132.838 172.190 137.168 1.00 54.74  ? 463 ILE C CG2 1 
ATOM   12822 C CD1 . ILE C 1 463 ? 135.018 172.547 139.452 1.00 54.57  ? 463 ILE C CD1 1 
ATOM   12823 N N   . TRP C 1 464 ? 132.720 169.298 135.717 1.00 60.40  ? 464 TRP C N   1 
ATOM   12824 C CA  . TRP C 1 464 ? 131.930 168.066 135.836 1.00 58.36  ? 464 TRP C CA  1 
ATOM   12825 C C   . TRP C 1 464 ? 132.539 166.836 135.142 1.00 60.81  ? 464 TRP C C   1 
ATOM   12826 O O   . TRP C 1 464 ? 132.127 165.710 135.417 1.00 61.27  ? 464 TRP C O   1 
ATOM   12827 C CB  . TRP C 1 464 ? 130.540 168.332 135.268 1.00 55.43  ? 464 TRP C CB  1 
ATOM   12828 N N   . ILE C 1 465 ? 133.528 167.037 134.266 1.00 62.50  ? 465 ILE C N   1 
ATOM   12829 C CA  . ILE C 1 465 ? 134.333 165.969 133.657 1.00 61.57  ? 465 ILE C CA  1 
ATOM   12830 C C   . ILE C 1 465 ? 135.797 165.960 134.136 1.00 59.78  ? 465 ILE C C   1 
ATOM   12831 O O   . ILE C 1 465 ? 136.449 164.925 134.086 1.00 60.51  ? 465 ILE C O   1 
ATOM   12832 C CB  . ILE C 1 465 ? 134.174 165.971 132.119 1.00 60.68  ? 465 ILE C CB  1 
ATOM   12833 C CG1 . ILE C 1 465 ? 134.724 167.229 131.431 1.00 58.73  ? 465 ILE C CG1 1 
ATOM   12834 C CG2 . ILE C 1 465 ? 132.702 165.707 131.762 1.00 59.27  ? 465 ILE C CG2 1 
ATOM   12835 C CD1 . ILE C 1 465 ? 134.738 167.125 129.908 1.00 49.76  ? 465 ILE C CD1 1 
ATOM   12836 N N   . SER C 1 466 ? 136.308 167.050 134.719 1.00 57.90  ? 466 SER C N   1 
ATOM   12837 C CA  . SER C 1 466 ? 137.674 167.155 135.270 1.00 60.94  ? 466 SER C CA  1 
ATOM   12838 C C   . SER C 1 466 ? 138.018 166.155 136.394 1.00 61.67  ? 466 SER C C   1 
ATOM   12839 O O   . SER C 1 466 ? 139.195 165.998 136.738 1.00 58.77  ? 466 SER C O   1 
ATOM   12840 C CB  . SER C 1 466 ? 137.903 168.566 135.808 1.00 59.24  ? 466 SER C CB  1 
ATOM   12841 O OG  . SER C 1 466 ? 137.245 168.755 137.046 1.00 59.01  ? 466 SER C OG  1 
ATOM   12842 N N   . PHE C 1 467 ? 137.008 165.492 136.964 1.00 64.14  ? 467 PHE C N   1 
ATOM   12843 C CA  . PHE C 1 467 ? 137.122 164.471 138.008 1.00 63.38  ? 467 PHE C CA  1 
ATOM   12844 C C   . PHE C 1 467 ? 136.535 163.098 137.607 1.00 64.85  ? 467 PHE C C   1 
ATOM   12845 O O   . PHE C 1 467 ? 136.504 162.193 138.437 1.00 66.48  ? 467 PHE C O   1 
ATOM   12846 C CB  . PHE C 1 467 ? 136.516 165.012 139.307 1.00 61.77  ? 467 PHE C CB  1 
ATOM   12847 C CG  . PHE C 1 467 ? 135.056 165.413 139.244 1.00 63.94  ? 467 PHE C CG  1 
ATOM   12848 C CD1 . PHE C 1 467 ? 134.047 164.433 139.245 1.00 65.46  ? 467 PHE C CD1 1 
ATOM   12849 C CD2 . PHE C 1 467 ? 134.697 166.772 139.275 1.00 61.80  ? 467 PHE C CD2 1 
ATOM   12850 C CE1 . PHE C 1 467 ? 132.695 164.809 139.274 1.00 65.01  ? 467 PHE C CE1 1 
ATOM   12851 C CE2 . PHE C 1 467 ? 133.349 167.149 139.315 1.00 63.57  ? 467 PHE C CE2 1 
ATOM   12852 C CZ  . PHE C 1 467 ? 132.345 166.169 139.311 1.00 62.69  ? 467 PHE C CZ  1 
ATOM   12853 N N   . MET C 1 468 ? 136.031 162.905 136.381 1.00 63.70  ? 468 MET C N   1 
ATOM   12854 C CA  . MET C 1 468 ? 135.203 161.727 136.055 1.00 64.67  ? 468 MET C CA  1 
ATOM   12855 C C   . MET C 1 468 ? 135.980 160.400 136.060 1.00 67.25  ? 468 MET C C   1 
ATOM   12856 O O   . MET C 1 468 ? 135.511 159.413 136.618 1.00 65.80  ? 468 MET C O   1 
ATOM   12857 C CB  . MET C 1 468 ? 134.458 161.949 134.729 1.00 65.54  ? 468 MET C CB  1 
ATOM   12858 C CG  . MET C 1 468 ? 135.334 161.890 133.479 1.00 66.00  ? 468 MET C CG  1 
ATOM   12859 S SD  . MET C 1 468 ? 134.493 162.450 131.981 1.00 77.49  ? 468 MET C SD  1 
ATOM   12860 C CE  . MET C 1 468 ? 135.944 162.694 130.933 1.00 61.89  ? 468 MET C CE  1 
ATOM   12861 N N   . ASP C 1 469 ? 137.192 160.388 135.498 1.00 60.77  ? 469 ASP C N   1 
ATOM   12862 C CA  . ASP C 1 469 ? 138.167 159.285 135.577 1.00 58.04  ? 469 ASP C CA  1 
ATOM   12863 C C   . ASP C 1 469 ? 139.345 159.636 136.506 1.00 52.71  ? 469 ASP C C   1 
ATOM   12864 O O   . ASP C 1 469 ? 140.326 158.897 136.606 1.00 53.60  ? 469 ASP C O   1 
ATOM   12865 C CB  . ASP C 1 469 ? 138.631 158.879 134.167 1.00 57.92  ? 469 ASP C CB  1 
ATOM   12866 C CG  . ASP C 1 469 ? 139.324 159.984 133.362 1.00 56.12  ? 469 ASP C CG  1 
ATOM   12867 O OD1 . ASP C 1 469 ? 139.452 161.125 133.847 1.00 57.25  ? 469 ASP C OD1 1 
ATOM   12868 O OD2 . ASP C 1 469 ? 139.710 159.709 132.209 1.00 59.63  ? 469 ASP C OD2 1 
ATOM   12869 N N   . SER C 1 470 ? 139.209 160.738 137.238 1.00 49.46  ? 470 SER C N   1 
ATOM   12870 C CA  . SER C 1 470 ? 140.221 161.462 138.013 1.00 49.45  ? 470 SER C CA  1 
ATOM   12871 C C   . SER C 1 470 ? 139.658 161.922 139.368 1.00 47.94  ? 470 SER C C   1 
ATOM   12872 O O   . SER C 1 470 ? 139.908 163.029 139.839 1.00 48.78  ? 470 SER C O   1 
ATOM   12873 C CB  . SER C 1 470 ? 140.739 162.625 137.163 1.00 49.69  ? 470 SER C CB  1 
ATOM   12874 O OG  . SER C 1 470 ? 139.635 163.343 136.661 1.00 54.89  ? 470 SER C OG  1 
ATOM   12875 N N   . TYR C 1 471 ? 138.886 161.049 140.024 1.00 39.18  ? 471 TYR C N   1 
ATOM   12876 C CA  . TYR C 1 471 ? 138.310 161.293 141.348 1.00 36.55  ? 471 TYR C CA  1 
ATOM   12877 C C   . TYR C 1 471 ? 139.365 161.490 142.442 1.00 32.12  ? 471 TYR C C   1 
ATOM   12878 O O   . TYR C 1 471 ? 139.049 162.021 143.497 1.00 37.34  ? 471 TYR C O   1 
ATOM   12879 C CB  . TYR C 1 471 ? 137.343 160.153 141.713 1.00 42.33  ? 471 TYR C CB  1 
ATOM   12880 C CG  . TYR C 1 471 ? 137.981 158.791 141.915 1.00 41.07  ? 471 TYR C CG  1 
ATOM   12881 C CD1 . TYR C 1 471 ? 138.890 158.593 142.971 1.00 40.91  ? 471 TYR C CD1 1 
ATOM   12882 C CD2 . TYR C 1 471 ? 137.650 157.710 141.081 1.00 44.05  ? 471 TYR C CD2 1 
ATOM   12883 C CE1 . TYR C 1 471 ? 139.557 157.376 143.130 1.00 39.87  ? 471 TYR C CE1 1 
ATOM   12884 C CE2 . TYR C 1 471 ? 138.256 156.454 141.292 1.00 46.66  ? 471 TYR C CE2 1 
ATOM   12885 C CZ  . TYR C 1 471 ? 139.239 156.297 142.295 1.00 45.92  ? 471 TYR C CZ  1 
ATOM   12886 O OH  . TYR C 1 471 ? 139.822 155.102 142.520 1.00 41.70  ? 471 TYR C OH  1 
ATOM   12887 N N   . PHE C 1 472 ? 140.627 161.106 142.230 1.00 29.54  ? 472 PHE C N   1 
ATOM   12888 C CA  . PHE C 1 472 ? 141.710 161.436 143.150 1.00 18.15  ? 472 PHE C CA  1 
ATOM   12889 C C   . PHE C 1 472 ? 141.887 162.939 143.319 1.00 18.77  ? 472 PHE C C   1 
ATOM   12890 O O   . PHE C 1 472 ? 142.322 163.362 144.376 1.00 37.88  ? 472 PHE C O   1 
ATOM   12891 C CB  . PHE C 1 472 ? 143.027 160.787 142.712 1.00 23.48  ? 472 PHE C CB  1 
ATOM   12892 C CG  . PHE C 1 472 ? 143.204 159.373 143.207 1.00 17.85  ? 472 PHE C CG  1 
ATOM   12893 C CD1 . PHE C 1 472 ? 143.298 159.139 144.588 1.00 20.34  ? 472 PHE C CD1 1 
ATOM   12894 C CD2 . PHE C 1 472 ? 143.306 158.301 142.307 1.00 21.46  ? 472 PHE C CD2 1 
ATOM   12895 C CE1 . PHE C 1 472 ? 143.467 157.836 145.070 1.00 17.43  ? 472 PHE C CE1 1 
ATOM   12896 C CE2 . PHE C 1 472 ? 143.506 157.000 142.792 1.00 19.70  ? 472 PHE C CE2 1 
ATOM   12897 C CZ  . PHE C 1 472 ? 143.585 156.773 144.173 1.00 22.00  ? 472 PHE C CZ  1 
ATOM   12898 N N   . GLU C 1 473 ? 141.496 163.778 142.367 1.00 28.40  ? 473 GLU C N   1 
ATOM   12899 C CA  . GLU C 1 473 ? 141.496 165.227 142.582 1.00 28.14  ? 473 GLU C CA  1 
ATOM   12900 C C   . GLU C 1 473 ? 140.420 165.650 143.603 1.00 29.94  ? 473 GLU C C   1 
ATOM   12901 O O   . GLU C 1 473 ? 140.631 166.536 144.421 1.00 34.40  ? 473 GLU C O   1 
ATOM   12902 C CB  . GLU C 1 473 ? 141.346 165.960 141.238 1.00 30.66  ? 473 GLU C CB  1 
ATOM   12903 C CG  . GLU C 1 473 ? 142.392 165.555 140.181 1.00 27.04  ? 473 GLU C CG  1 
ATOM   12904 C CD  . GLU C 1 473 ? 143.854 165.759 140.613 1.00 38.11  ? 473 GLU C CD  1 
ATOM   12905 O OE1 . GLU C 1 473 ? 144.240 166.860 141.051 1.00 39.24  ? 473 GLU C OE1 1 
ATOM   12906 O OE2 . GLU C 1 473 ? 144.642 164.786 140.521 1.00 47.14  ? 473 GLU C OE2 1 
ATOM   12907 N N   . ILE C 1 474 ? 139.276 164.965 143.658 1.00 34.79  ? 474 ILE C N   1 
ATOM   12908 C CA  . ILE C 1 474 ? 138.307 165.135 144.749 1.00 25.72  ? 474 ILE C CA  1 
ATOM   12909 C C   . ILE C 1 474 ? 138.869 164.579 146.066 1.00 27.11  ? 474 ILE C C   1 
ATOM   12910 O O   . ILE C 1 474 ? 138.786 165.249 147.088 1.00 37.13  ? 474 ILE C O   1 
ATOM   12911 C CB  . ILE C 1 474 ? 136.932 164.523 144.383 1.00 32.78  ? 474 ILE C CB  1 
ATOM   12912 C CG1 . ILE C 1 474 ? 136.307 165.338 143.235 1.00 32.02  ? 474 ILE C CG1 1 
ATOM   12913 C CG2 . ILE C 1 474 ? 135.991 164.488 145.601 1.00 28.37  ? 474 ILE C CG2 1 
ATOM   12914 C CD1 . ILE C 1 474 ? 134.973 164.807 142.712 1.00 36.89  ? 474 ILE C CD1 1 
ATOM   12915 N N   . LEU C 1 475 ? 139.460 163.381 146.075 1.00 25.68  ? 475 LEU C N   1 
ATOM   12916 C CA  . LEU C 1 475 ? 139.956 162.755 147.303 1.00 17.93  ? 475 LEU C CA  1 
ATOM   12917 C C   . LEU C 1 475 ? 141.167 163.473 147.915 1.00 19.70  ? 475 LEU C C   1 
ATOM   12918 O O   . LEU C 1 475 ? 141.254 163.574 149.136 1.00 30.74  ? 475 LEU C O   1 
ATOM   12919 C CB  . LEU C 1 475 ? 140.278 161.274 147.074 1.00 28.40  ? 475 LEU C CB  1 
ATOM   12920 C CG  . LEU C 1 475 ? 139.116 160.392 146.590 1.00 26.69  ? 475 LEU C CG  1 
ATOM   12921 C CD1 . LEU C 1 475 ? 139.627 158.977 146.366 1.00 29.50  ? 475 LEU C CD1 1 
ATOM   12922 C CD2 . LEU C 1 475 ? 137.942 160.332 147.557 1.00 17.91  ? 475 LEU C CD2 1 
ATOM   12923 N N   . PHE C 1 476 ? 142.087 164.016 147.116 1.00 13.50  ? 476 PHE C N   1 
ATOM   12924 C CA  . PHE C 1 476 ? 143.175 164.864 147.606 1.00 9.69   ? 476 PHE C CA  1 
ATOM   12925 C C   . PHE C 1 476 ? 142.660 166.202 148.146 1.00 11.47  ? 476 PHE C C   1 
ATOM   12926 O O   . PHE C 1 476 ? 143.133 166.636 149.191 1.00 22.61  ? 476 PHE C O   1 
ATOM   12927 C CB  . PHE C 1 476 ? 144.238 165.071 146.522 1.00 13.93  ? 476 PHE C CB  1 
ATOM   12928 C CG  . PHE C 1 476 ? 145.332 164.017 146.473 1.00 11.99  ? 476 PHE C CG  1 
ATOM   12929 C CD1 . PHE C 1 476 ? 145.113 162.762 145.883 1.00 13.79  ? 476 PHE C CD1 1 
ATOM   12930 C CD2 . PHE C 1 476 ? 146.600 164.309 147.003 1.00 9.56   ? 476 PHE C CD2 1 
ATOM   12931 C CE1 . PHE C 1 476 ? 146.154 161.830 145.780 1.00 10.13  ? 476 PHE C CE1 1 
ATOM   12932 C CE2 . PHE C 1 476 ? 147.639 163.374 146.910 1.00 13.54  ? 476 PHE C CE2 1 
ATOM   12933 C CZ  . PHE C 1 476 ? 147.420 162.138 146.289 1.00 9.53   ? 476 PHE C CZ  1 
ATOM   12934 N N   . LEU C 1 477 ? 141.660 166.828 147.511 1.00 24.46  ? 477 LEU C N   1 
ATOM   12935 C CA  . LEU C 1 477 ? 141.012 168.027 148.043 1.00 27.82  ? 477 LEU C CA  1 
ATOM   12936 C C   . LEU C 1 477 ? 140.316 167.758 149.382 1.00 22.59  ? 477 LEU C C   1 
ATOM   12937 O O   . LEU C 1 477 ? 140.515 168.498 150.341 1.00 31.90  ? 477 LEU C O   1 
ATOM   12938 C CB  . LEU C 1 477 ? 140.014 168.586 147.007 1.00 27.64  ? 477 LEU C CB  1 
ATOM   12939 C CG  . LEU C 1 477 ? 139.287 169.863 147.462 1.00 29.88  ? 477 LEU C CG  1 
ATOM   12940 C CD1 . LEU C 1 477 ? 140.216 171.063 147.503 1.00 27.58  ? 477 LEU C CD1 1 
ATOM   12941 C CD2 . LEU C 1 477 ? 138.137 170.183 146.522 1.00 29.74  ? 477 LEU C CD2 1 
ATOM   12942 N N   . LEU C 1 478 ? 139.530 166.683 149.469 1.00 25.68  ? 478 LEU C N   1 
ATOM   12943 C CA  . LEU C 1 478 ? 138.833 166.289 150.687 1.00 20.98  ? 478 LEU C CA  1 
ATOM   12944 C C   . LEU C 1 478 ? 139.806 165.976 151.828 1.00 18.21  ? 478 LEU C C   1 
ATOM   12945 O O   . LEU C 1 478 ? 139.598 166.437 152.945 1.00 31.35  ? 478 LEU C O   1 
ATOM   12946 C CB  . LEU C 1 478 ? 137.891 165.124 150.363 1.00 28.45  ? 478 LEU C CB  1 
ATOM   12947 C CG  . LEU C 1 478 ? 137.082 164.606 151.559 1.00 36.43  ? 478 LEU C CG  1 
ATOM   12948 C CD1 . LEU C 1 478 ? 136.131 165.654 152.118 1.00 27.98  ? 478 LEU C CD1 1 
ATOM   12949 C CD2 . LEU C 1 478 ? 136.286 163.378 151.142 1.00 27.32  ? 478 LEU C CD2 1 
ATOM   12950 N N   . GLN C 1 479 ? 140.907 165.268 151.572 1.00 17.57  ? 479 GLN C N   1 
ATOM   12951 C CA  . GLN C 1 479 ? 141.924 164.996 152.588 1.00 17.28  ? 479 GLN C CA  1 
ATOM   12952 C C   . GLN C 1 479 ? 142.558 166.272 153.133 1.00 20.46  ? 479 GLN C C   1 
ATOM   12953 O O   . GLN C 1 479 ? 142.725 166.413 154.340 1.00 28.93  ? 479 GLN C O   1 
ATOM   12954 C CB  . GLN C 1 479 ? 142.993 164.071 151.996 1.00 19.84  ? 479 GLN C CB  1 
ATOM   12955 C CG  . GLN C 1 479 ? 143.819 163.322 153.048 1.00 19.43  ? 479 GLN C CG  1 
ATOM   12956 C CD  . GLN C 1 479 ? 145.065 164.007 153.608 1.00 21.70  ? 479 GLN C CD  1 
ATOM   12957 O OE1 . GLN C 1 479 ? 145.620 164.952 153.074 1.00 23.79  ? 479 GLN C OE1 1 
ATOM   12958 N NE2 . GLN C 1 479 ? 145.585 163.498 154.696 1.00 30.31  ? 479 GLN C NE2 1 
ATOM   12959 N N   . ALA C 1 480 ? 142.870 167.229 152.263 1.00 28.61  ? 480 ALA C N   1 
ATOM   12960 C CA  . ALA C 1 480 ? 143.434 168.509 152.638 1.00 24.18  ? 480 ALA C CA  1 
ATOM   12961 C C   . ALA C 1 480 ? 142.445 169.372 153.442 1.00 24.10  ? 480 ALA C C   1 
ATOM   12962 O O   . ALA C 1 480 ? 142.820 169.927 154.470 1.00 27.06  ? 480 ALA C O   1 
ATOM   12963 C CB  . ALA C 1 480 ? 143.895 169.186 151.358 1.00 29.88  ? 480 ALA C CB  1 
ATOM   12964 N N   . LEU C 1 481 ? 141.165 169.426 153.050 1.00 24.01  ? 481 LEU C N   1 
ATOM   12965 C CA  . LEU C 1 481 ? 140.105 170.078 153.825 1.00 28.63  ? 481 LEU C CA  1 
ATOM   12966 C C   . LEU C 1 481 ? 139.955 169.473 155.225 1.00 29.78  ? 481 LEU C C   1 
ATOM   12967 O O   . LEU C 1 481 ? 140.036 170.198 156.212 1.00 33.93  ? 481 LEU C O   1 
ATOM   12968 C CB  . LEU C 1 481 ? 138.761 169.984 153.081 1.00 31.27  ? 481 LEU C CB  1 
ATOM   12969 C CG  . LEU C 1 481 ? 138.600 170.962 151.911 1.00 35.54  ? 481 LEU C CG  1 
ATOM   12970 C CD1 . LEU C 1 481 ? 137.326 170.629 151.141 1.00 35.61  ? 481 LEU C CD1 1 
ATOM   12971 C CD2 . LEU C 1 481 ? 138.490 172.405 152.399 1.00 31.02  ? 481 LEU C CD2 1 
ATOM   12972 N N   . LEU C 1 482 ? 139.776 168.155 155.327 1.00 33.85  ? 482 LEU C N   1 
ATOM   12973 C CA  . LEU C 1 482 ? 139.629 167.467 156.611 1.00 26.18  ? 482 LEU C CA  1 
ATOM   12974 C C   . LEU C 1 482 ? 140.878 167.621 157.486 1.00 19.12  ? 482 LEU C C   1 
ATOM   12975 O O   . LEU C 1 482 ? 140.762 167.762 158.700 1.00 32.65  ? 482 LEU C O   1 
ATOM   12976 C CB  . LEU C 1 482 ? 139.297 165.990 156.373 1.00 30.20  ? 482 LEU C CB  1 
ATOM   12977 C CG  . LEU C 1 482 ? 137.956 165.711 155.684 1.00 30.29  ? 482 LEU C CG  1 
ATOM   12978 C CD1 . LEU C 1 482 ? 137.879 164.224 155.357 1.00 28.26  ? 482 LEU C CD1 1 
ATOM   12979 C CD2 . LEU C 1 482 ? 136.763 166.072 156.555 1.00 29.62  ? 482 LEU C CD2 1 
ATOM   12980 N N   . THR C 1 483 ? 142.065 167.696 156.884 1.00 25.03  ? 483 THR C N   1 
ATOM   12981 C CA  . THR C 1 483 ? 143.305 167.991 157.600 1.00 25.83  ? 483 THR C CA  1 
ATOM   12982 C C   . THR C 1 483 ? 143.289 169.390 158.196 1.00 30.04  ? 483 THR C C   1 
ATOM   12983 O O   . THR C 1 483 ? 143.496 169.528 159.395 1.00 40.80  ? 483 THR C O   1 
ATOM   12984 C CB  . THR C 1 483 ? 144.528 167.833 156.698 1.00 27.38  ? 483 THR C CB  1 
ATOM   12985 O OG1 . THR C 1 483 ? 144.575 166.523 156.220 1.00 38.10  ? 483 THR C OG1 1 
ATOM   12986 C CG2 . THR C 1 483 ? 145.826 168.086 157.449 1.00 29.80  ? 483 THR C CG2 1 
ATOM   12987 N N   . VAL C 1 484 ? 142.997 170.428 157.411 1.00 40.82  ? 484 VAL C N   1 
ATOM   12988 C CA  . VAL C 1 484 ? 142.933 171.809 157.901 1.00 37.48  ? 484 VAL C CA  1 
ATOM   12989 C C   . VAL C 1 484 ? 141.830 171.966 158.947 1.00 37.25  ? 484 VAL C C   1 
ATOM   12990 O O   . VAL C 1 484 ? 142.094 172.488 160.025 1.00 46.32  ? 484 VAL C O   1 
ATOM   12991 C CB  . VAL C 1 484 ? 142.790 172.796 156.725 1.00 37.10  ? 484 VAL C CB  1 
ATOM   12992 C CG1 . VAL C 1 484 ? 142.576 174.237 157.186 1.00 39.12  ? 484 VAL C CG1 1 
ATOM   12993 C CG2 . VAL C 1 484 ? 144.060 172.780 155.876 1.00 37.14  ? 484 VAL C CG2 1 
ATOM   12994 N N   . LEU C 1 485 ? 140.637 171.421 158.712 1.00 38.90  ? 485 LEU C N   1 
ATOM   12995 C CA  . LEU C 1 485 ? 139.558 171.414 159.698 1.00 39.37  ? 485 LEU C CA  1 
ATOM   12996 C C   . LEU C 1 485 ? 139.966 170.709 160.995 1.00 41.24  ? 485 LEU C C   1 
ATOM   12997 O O   . LEU C 1 485 ? 139.716 171.246 162.065 1.00 44.83  ? 485 LEU C O   1 
ATOM   12998 C CB  . LEU C 1 485 ? 138.292 170.784 159.102 1.00 37.67  ? 485 LEU C CB  1 
ATOM   12999 C CG  . LEU C 1 485 ? 137.609 171.659 158.043 1.00 48.38  ? 485 LEU C CG  1 
ATOM   13000 C CD1 . LEU C 1 485 ? 136.561 170.840 157.296 1.00 45.48  ? 485 LEU C CD1 1 
ATOM   13001 C CD2 . LEU C 1 485 ? 136.930 172.874 158.672 1.00 46.90  ? 485 LEU C CD2 1 
ATOM   13002 N N   . SER C 1 486 ? 140.653 169.567 160.943 1.00 40.41  ? 486 SER C N   1 
ATOM   13003 C CA  . SER C 1 486 ? 141.129 168.896 162.160 1.00 34.06  ? 486 SER C CA  1 
ATOM   13004 C C   . SER C 1 486 ? 142.086 169.771 162.972 1.00 40.08  ? 486 SER C C   1 
ATOM   13005 O O   . SER C 1 486 ? 142.000 169.789 164.192 1.00 47.40  ? 486 SER C O   1 
ATOM   13006 C CB  . SER C 1 486 ? 141.770 167.545 161.843 1.00 34.81  ? 486 SER C CB  1 
ATOM   13007 O OG  . SER C 1 486 ? 143.056 167.677 161.287 1.00 41.13  ? 486 SER C OG  1 
ATOM   13008 N N   . GLN C 1 487 ? 142.948 170.563 162.332 1.00 45.19  ? 487 GLN C N   1 
ATOM   13009 C CA  . GLN C 1 487 ? 143.846 171.486 163.029 1.00 44.12  ? 487 GLN C CA  1 
ATOM   13010 C C   . GLN C 1 487 ? 143.116 172.711 163.593 1.00 44.29  ? 487 GLN C C   1 
ATOM   13011 O O   . GLN C 1 487 ? 143.413 173.135 164.705 1.00 47.22  ? 487 GLN C O   1 
ATOM   13012 C CB  . GLN C 1 487 ? 144.986 171.906 162.097 1.00 44.22  ? 487 GLN C CB  1 
ATOM   13013 C CG  . GLN C 1 487 ? 145.838 170.721 161.626 1.00 43.31  ? 487 GLN C CG  1 
ATOM   13014 C CD  . GLN C 1 487 ? 146.352 169.861 162.769 1.00 45.13  ? 487 GLN C CD  1 
ATOM   13015 O OE1 . GLN C 1 487 ? 146.954 170.339 163.716 1.00 51.78  ? 487 GLN C OE1 1 
ATOM   13016 N NE2 . GLN C 1 487 ? 146.119 168.568 162.741 1.00 45.83  ? 487 GLN C NE2 1 
ATOM   13017 N N   . VAL C 1 488 ? 142.099 173.229 162.898 1.00 48.48  ? 488 VAL C N   1 
ATOM   13018 C CA  . VAL C 1 488 ? 141.207 174.274 163.424 1.00 49.13  ? 488 VAL C CA  1 
ATOM   13019 C C   . VAL C 1 488 ? 140.444 173.778 164.656 1.00 51.61  ? 488 VAL C C   1 
ATOM   13020 O O   . VAL C 1 488 ? 140.467 174.431 165.696 1.00 53.86  ? 488 VAL C O   1 
ATOM   13021 C CB  . VAL C 1 488 ? 140.245 174.763 162.323 1.00 48.60  ? 488 VAL C CB  1 
ATOM   13022 C CG1 . VAL C 1 488 ? 139.165 175.707 162.852 1.00 50.61  ? 488 VAL C CG1 1 
ATOM   13023 C CG2 . VAL C 1 488 ? 141.017 175.509 161.231 1.00 45.73  ? 488 VAL C CG2 1 
ATOM   13024 N N   . LEU C 1 489 ? 139.832 172.592 164.598 1.00 49.63  ? 489 LEU C N   1 
ATOM   13025 C CA  . LEU C 1 489 ? 139.141 172.002 165.747 1.00 44.98  ? 489 LEU C CA  1 
ATOM   13026 C C   . LEU C 1 489 ? 140.098 171.702 166.909 1.00 44.76  ? 489 LEU C C   1 
ATOM   13027 O O   . LEU C 1 489 ? 139.723 171.876 168.066 1.00 53.42  ? 489 LEU C O   1 
ATOM   13028 C CB  . LEU C 1 489 ? 138.391 170.728 165.324 1.00 48.57  ? 489 LEU C CB  1 
ATOM   13029 C CG  . LEU C 1 489 ? 137.213 170.895 164.350 1.00 47.46  ? 489 LEU C CG  1 
ATOM   13030 C CD1 . LEU C 1 489 ? 136.317 169.663 164.457 1.00 45.55  ? 489 LEU C CD1 1 
ATOM   13031 C CD2 . LEU C 1 489 ? 136.343 172.122 164.617 1.00 47.28  ? 489 LEU C CD2 1 
ATOM   13032 N N   . ARG C 1 490 ? 141.343 171.308 166.629 1.00 42.08  ? 490 ARG C N   1 
ATOM   13033 C CA  . ARG C 1 490 ? 142.384 171.113 167.645 1.00 47.42  ? 490 ARG C CA  1 
ATOM   13034 C C   . ARG C 1 490 ? 142.762 172.424 168.340 1.00 52.44  ? 490 ARG C C   1 
ATOM   13035 O O   . ARG C 1 490 ? 142.897 172.436 169.559 1.00 58.06  ? 490 ARG C O   1 
ATOM   13036 C CB  . ARG C 1 490 ? 143.589 170.439 166.984 1.00 49.96  ? 490 ARG C CB  1 
ATOM   13037 C CG  . ARG C 1 490 ? 144.660 170.047 167.995 1.00 44.81  ? 490 ARG C CG  1 
ATOM   13038 C CD  . ARG C 1 490 ? 145.881 169.487 167.272 1.00 50.55  ? 490 ARG C CD  1 
ATOM   13039 N NE  . ARG C 1 490 ? 147.029 169.380 168.187 1.00 57.82  ? 490 ARG C NE  1 
ATOM   13040 C CZ  . ARG C 1 490 ? 147.862 170.338 168.543 1.00 54.27  ? 490 ARG C CZ  1 
ATOM   13041 N NH1 . ARG C 1 490 ? 148.796 170.110 169.412 1.00 53.12  ? 490 ARG C NH1 1 
ATOM   13042 N NH2 . ARG C 1 490 ? 147.783 171.538 168.066 1.00 49.85  ? 490 ARG C NH2 1 
ATOM   13043 N N   . PHE C 1 491 ? 142.874 173.540 167.614 1.00 57.86  ? 491 PHE C N   1 
ATOM   13044 C CA  . PHE C 1 491 ? 143.068 174.867 168.225 1.00 57.35  ? 491 PHE C CA  1 
ATOM   13045 C C   . PHE C 1 491 ? 141.853 175.328 169.054 1.00 60.68  ? 491 PHE C C   1 
ATOM   13046 O O   . PHE C 1 491 ? 142.030 175.937 170.107 1.00 62.21  ? 491 PHE C O   1 
ATOM   13047 C CB  . PHE C 1 491 ? 143.401 175.906 167.146 1.00 56.81  ? 491 PHE C CB  1 
ATOM   13048 C CG  . PHE C 1 491 ? 144.664 175.679 166.330 1.00 60.54  ? 491 PHE C CG  1 
ATOM   13049 C CD1 . PHE C 1 491 ? 145.812 175.088 166.893 1.00 60.16  ? 491 PHE C CD1 1 
ATOM   13050 C CD2 . PHE C 1 491 ? 144.708 176.126 164.992 1.00 60.86  ? 491 PHE C CD2 1 
ATOM   13051 C CE1 . PHE C 1 491 ? 146.980 174.937 166.127 1.00 58.92  ? 491 PHE C CE1 1 
ATOM   13052 C CE2 . PHE C 1 491 ? 145.875 175.968 164.226 1.00 60.13  ? 491 PHE C CE2 1 
ATOM   13053 C CZ  . PHE C 1 491 ? 147.015 175.378 164.795 1.00 60.90  ? 491 PHE C CZ  1 
ATOM   13054 N N   . MET C 1 492 ? 140.629 174.989 168.643 1.00 59.42  ? 492 MET C N   1 
ATOM   13055 C CA  . MET C 1 492 ? 139.410 175.172 169.450 1.00 58.85  ? 492 MET C CA  1 
ATOM   13056 C C   . MET C 1 492 ? 139.292 174.205 170.645 1.00 60.65  ? 492 MET C C   1 
ATOM   13057 O O   . MET C 1 492 ? 138.369 174.334 171.446 1.00 63.29  ? 492 MET C O   1 
ATOM   13058 C CB  . MET C 1 492 ? 138.169 175.037 168.557 1.00 59.12  ? 492 MET C CB  1 
ATOM   13059 C CG  . MET C 1 492 ? 138.065 176.135 167.501 1.00 61.62  ? 492 MET C CG  1 
ATOM   13060 S SD  . MET C 1 492 ? 136.613 175.935 166.441 1.00 73.56  ? 492 MET C SD  1 
ATOM   13061 C CE  . MET C 1 492 ? 136.809 177.402 165.407 1.00 60.99  ? 492 MET C CE  1 
ATOM   13062 N N   . GLU C 1 493 ? 140.207 173.244 170.781 1.00 60.82  ? 493 GLU C N   1 
ATOM   13063 C CA  . GLU C 1 493 ? 140.225 172.210 171.818 1.00 61.95  ? 493 GLU C CA  1 
ATOM   13064 C C   . GLU C 1 493 ? 138.973 171.311 171.902 1.00 61.67  ? 493 GLU C C   1 
ATOM   13065 O O   . GLU C 1 493 ? 138.730 170.699 172.942 1.00 62.54  ? 493 GLU C O   1 
ATOM   13066 C CB  . GLU C 1 493 ? 140.588 172.850 173.157 1.00 59.14  ? 493 GLU C CB  1 
ATOM   13067 N N   . THR C 1 494 ? 138.166 171.202 170.840 1.00 56.06  ? 494 THR C N   1 
ATOM   13068 C CA  . THR C 1 494 ? 137.003 170.290 170.818 1.00 58.27  ? 494 THR C CA  1 
ATOM   13069 C C   . THR C 1 494 ? 137.425 168.846 170.543 1.00 56.70  ? 494 THR C C   1 
ATOM   13070 O O   . THR C 1 494 ? 138.340 168.608 169.759 1.00 59.02  ? 494 THR C O   1 
ATOM   13071 C CB  . THR C 1 494 ? 135.913 170.769 169.847 1.00 57.68  ? 494 THR C CB  1 
ATOM   13072 O OG1 . THR C 1 494 ? 134.766 169.964 169.975 1.00 58.53  ? 494 THR C OG1 1 
ATOM   13073 C CG2 . THR C 1 494 ? 136.292 170.722 168.372 1.00 54.73  ? 494 THR C CG2 1 
ATOM   13074 N N   . GLU C 1 495 ? 136.772 167.851 171.151 1.00 57.16  ? 495 GLU C N   1 
ATOM   13075 C CA  . GLU C 1 495 ? 137.145 166.433 171.002 1.00 56.33  ? 495 GLU C CA  1 
ATOM   13076 C C   . GLU C 1 495 ? 137.045 165.920 169.555 1.00 56.47  ? 495 GLU C C   1 
ATOM   13077 O O   . GLU C 1 495 ? 137.797 165.037 169.145 1.00 59.53  ? 495 GLU C O   1 
ATOM   13078 C CB  . GLU C 1 495 ? 136.293 165.572 171.948 1.00 57.57  ? 495 GLU C CB  1 
ATOM   13079 C CG  . GLU C 1 495 ? 134.816 165.449 171.531 1.00 58.05  ? 495 GLU C CG  1 
ATOM   13080 C CD  . GLU C 1 495 ? 133.980 164.643 172.534 1.00 60.80  ? 495 GLU C CD  1 
ATOM   13081 O OE1 . GLU C 1 495 ? 134.473 163.646 173.100 1.00 58.61  ? 495 GLU C OE1 1 
ATOM   13082 O OE2 . GLU C 1 495 ? 132.803 164.991 172.770 1.00 62.34  ? 495 GLU C OE2 1 
ATOM   13083 N N   . TRP C 1 496 ? 136.157 166.507 168.754 1.00 48.41  ? 496 TRP C N   1 
ATOM   13084 C CA  . TRP C 1 496 ? 135.884 166.106 167.376 1.00 47.81  ? 496 TRP C CA  1 
ATOM   13085 C C   . TRP C 1 496 ? 137.036 166.357 166.401 1.00 50.21  ? 496 TRP C C   1 
ATOM   13086 O O   . TRP C 1 496 ? 136.973 165.916 165.255 1.00 51.33  ? 496 TRP C O   1 
ATOM   13087 C CB  . TRP C 1 496 ? 134.572 166.755 166.923 1.00 48.86  ? 496 TRP C CB  1 
ATOM   13088 C CG  . TRP C 1 496 ? 133.419 166.257 167.729 1.00 54.42  ? 496 TRP C CG  1 
ATOM   13089 C CD1 . TRP C 1 496 ? 132.829 166.907 168.757 1.00 52.13  ? 496 TRP C CD1 1 
ATOM   13090 C CD2 . TRP C 1 496 ? 132.811 164.932 167.686 1.00 57.48  ? 496 TRP C CD2 1 
ATOM   13091 N NE1 . TRP C 1 496 ? 131.926 166.062 169.372 1.00 52.46  ? 496 TRP C NE1 1 
ATOM   13092 C CE2 . TRP C 1 496 ? 131.900 164.821 168.774 1.00 56.74  ? 496 TRP C CE2 1 
ATOM   13093 C CE3 . TRP C 1 496 ? 132.970 163.799 166.858 1.00 51.11  ? 496 TRP C CE3 1 
ATOM   13094 C CZ2 . TRP C 1 496 ? 131.211 163.635 169.052 1.00 53.74  ? 496 TRP C CZ2 1 
ATOM   13095 C CZ3 . TRP C 1 496 ? 132.283 162.602 167.126 1.00 52.30  ? 496 TRP C CZ3 1 
ATOM   13096 C CH2 . TRP C 1 496 ? 131.414 162.516 168.229 1.00 53.97  ? 496 TRP C CH2 1 
ATOM   13097 N N   . TYR C 1 497 ? 138.121 166.999 166.838 1.00 44.51  ? 497 TYR C N   1 
ATOM   13098 C CA  . TYR C 1 497 ? 139.336 167.067 166.038 1.00 41.00  ? 497 TYR C CA  1 
ATOM   13099 C C   . TYR C 1 497 ? 139.906 165.672 165.744 1.00 41.34  ? 497 TYR C C   1 
ATOM   13100 O O   . TYR C 1 497 ? 140.398 165.450 164.641 1.00 44.27  ? 497 TYR C O   1 
ATOM   13101 C CB  . TYR C 1 497 ? 140.364 167.980 166.720 1.00 40.74  ? 497 TYR C CB  1 
ATOM   13102 C CG  . TYR C 1 497 ? 141.431 167.277 167.525 1.00 38.88  ? 497 TYR C CG  1 
ATOM   13103 C CD1 . TYR C 1 497 ? 142.615 166.834 166.902 1.00 40.78  ? 497 TYR C CD1 1 
ATOM   13104 C CD2 . TYR C 1 497 ? 141.217 167.021 168.885 1.00 39.73  ? 497 TYR C CD2 1 
ATOM   13105 C CE1 . TYR C 1 497 ? 143.576 166.119 167.642 1.00 38.91  ? 497 TYR C CE1 1 
ATOM   13106 C CE2 . TYR C 1 497 ? 142.171 166.314 169.626 1.00 44.05  ? 497 TYR C CE2 1 
ATOM   13107 C CZ  . TYR C 1 497 ? 143.346 165.853 169.008 1.00 45.76  ? 497 TYR C CZ  1 
ATOM   13108 O OH  . TYR C 1 497 ? 144.250 165.163 169.741 1.00 48.24  ? 497 TYR C OH  1 
ATOM   13109 N N   . LEU C 1 498 ? 139.814 164.724 166.684 1.00 35.89  ? 498 LEU C N   1 
ATOM   13110 C CA  . LEU C 1 498 ? 140.463 163.421 166.555 1.00 32.29  ? 498 LEU C CA  1 
ATOM   13111 C C   . LEU C 1 498 ? 139.796 162.517 165.498 1.00 34.76  ? 498 LEU C C   1 
ATOM   13112 O O   . LEU C 1 498 ? 140.513 162.014 164.638 1.00 33.51  ? 498 LEU C O   1 
ATOM   13113 C CB  . LEU C 1 498 ? 140.650 162.778 167.943 1.00 34.90  ? 498 LEU C CB  1 
ATOM   13114 C CG  . LEU C 1 498 ? 141.436 161.458 167.913 1.00 36.78  ? 498 LEU C CG  1 
ATOM   13115 C CD1 . LEU C 1 498 ? 142.898 161.682 167.542 1.00 35.26  ? 498 LEU C CD1 1 
ATOM   13116 C CD2 . LEU C 1 498 ? 141.389 160.781 169.276 1.00 34.72  ? 498 LEU C CD2 1 
ATOM   13117 N N   . PRO C 1 499 ? 138.461 162.364 165.441 1.00 34.18  ? 499 PRO C N   1 
ATOM   13118 C CA  . PRO C 1 499 ? 137.776 161.775 164.291 1.00 30.00  ? 499 PRO C CA  1 
ATOM   13119 C C   . PRO C 1 499 ? 138.126 162.404 162.936 1.00 32.61  ? 499 PRO C C   1 
ATOM   13120 O O   . PRO C 1 499 ? 138.333 161.668 161.977 1.00 34.63  ? 499 PRO C O   1 
ATOM   13121 C CB  . PRO C 1 499 ? 136.286 161.930 164.593 1.00 31.86  ? 499 PRO C CB  1 
ATOM   13122 C CG  . PRO C 1 499 ? 136.243 161.860 166.107 1.00 28.66  ? 499 PRO C CG  1 
ATOM   13123 C CD  . PRO C 1 499 ? 137.518 162.570 166.526 1.00 26.88  ? 499 PRO C CD  1 
ATOM   13124 N N   . LEU C 1 500 ? 138.247 163.735 162.826 1.00 31.27  ? 500 LEU C N   1 
ATOM   13125 C CA  . LEU C 1 500 ? 138.657 164.380 161.571 1.00 28.70  ? 500 LEU C CA  1 
ATOM   13126 C C   . LEU C 1 500 ? 140.118 164.100 161.214 1.00 28.93  ? 500 LEU C C   1 
ATOM   13127 O O   . LEU C 1 500 ? 140.414 163.833 160.053 1.00 35.11  ? 500 LEU C O   1 
ATOM   13128 C CB  . LEU C 1 500 ? 138.436 165.901 161.611 1.00 34.27  ? 500 LEU C CB  1 
ATOM   13129 C CG  . LEU C 1 500 ? 136.988 166.394 161.695 1.00 37.55  ? 500 LEU C CG  1 
ATOM   13130 C CD1 . LEU C 1 500 ? 136.996 167.902 161.452 1.00 38.08  ? 500 LEU C CD1 1 
ATOM   13131 C CD2 . LEU C 1 500 ? 136.082 165.765 160.646 1.00 33.87  ? 500 LEU C CD2 1 
ATOM   13132 N N   . LEU C 1 501 ? 141.033 164.129 162.181 1.00 20.11  ? 501 LEU C N   1 
ATOM   13133 C CA  . LEU C 1 501 ? 142.440 163.794 161.973 1.00 22.94  ? 501 LEU C CA  1 
ATOM   13134 C C   . LEU C 1 501 ? 142.596 162.344 161.508 1.00 22.34  ? 501 LEU C C   1 
ATOM   13135 O O   . LEU C 1 501 ? 143.328 162.061 160.566 1.00 31.03  ? 501 LEU C O   1 
ATOM   13136 C CB  . LEU C 1 501 ? 143.207 164.048 163.282 1.00 23.64  ? 501 LEU C CB  1 
ATOM   13137 C CG  . LEU C 1 501 ? 144.724 163.829 163.167 1.00 24.14  ? 501 LEU C CG  1 
ATOM   13138 C CD1 . LEU C 1 501 ? 145.384 165.002 162.449 1.00 26.78  ? 501 LEU C CD1 1 
ATOM   13139 C CD2 . LEU C 1 501 ? 145.349 163.694 164.546 1.00 27.36  ? 501 LEU C CD2 1 
ATOM   13140 N N   . VAL C 1 502 ? 141.871 161.425 162.129 1.00 32.50  ? 502 VAL C N   1 
ATOM   13141 C CA  . VAL C 1 502 ? 141.872 159.999 161.800 1.00 26.40  ? 502 VAL C CA  1 
ATOM   13142 C C   . VAL C 1 502 ? 141.200 159.716 160.451 1.00 22.48  ? 502 VAL C C   1 
ATOM   13143 O O   . VAL C 1 502 ? 141.723 158.925 159.676 1.00 33.73  ? 502 VAL C O   1 
ATOM   13144 C CB  . VAL C 1 502 ? 141.258 159.217 162.975 1.00 27.86  ? 502 VAL C CB  1 
ATOM   13145 C CG1 . VAL C 1 502 ? 140.997 157.763 162.635 1.00 25.75  ? 502 VAL C CG1 1 
ATOM   13146 C CG2 . VAL C 1 502 ? 142.231 159.229 164.159 1.00 19.38  ? 502 VAL C CG2 1 
ATOM   13147 N N   . LEU C 1 503 ? 140.112 160.396 160.093 1.00 17.67  ? 503 LEU C N   1 
ATOM   13148 C CA  . LEU C 1 503 ? 139.518 160.281 158.758 1.00 22.29  ? 503 LEU C CA  1 
ATOM   13149 C C   . LEU C 1 503 ? 140.453 160.829 157.665 1.00 24.64  ? 503 LEU C C   1 
ATOM   13150 O O   . LEU C 1 503 ? 140.595 160.221 156.608 1.00 33.37  ? 503 LEU C O   1 
ATOM   13151 C CB  . LEU C 1 503 ? 138.140 160.965 158.757 1.00 29.73  ? 503 LEU C CB  1 
ATOM   13152 C CG  . LEU C 1 503 ? 137.403 160.909 157.405 1.00 33.12  ? 503 LEU C CG  1 
ATOM   13153 C CD1 . LEU C 1 503 ? 137.128 159.487 156.928 1.00 31.91  ? 503 LEU C CD1 1 
ATOM   13154 C CD2 . LEU C 1 503 ? 136.075 161.648 157.514 1.00 27.39  ? 503 LEU C CD2 1 
ATOM   13155 N N   . SER C 1 504 ? 141.156 161.929 157.936 1.00 26.84  ? 504 SER C N   1 
ATOM   13156 C CA  . SER C 1 504 ? 142.194 162.484 157.060 1.00 18.01  ? 504 SER C CA  1 
ATOM   13157 C C   . SER C 1 504 ? 143.381 161.548 156.891 1.00 18.47  ? 504 SER C C   1 
ATOM   13158 O O   . SER C 1 504 ? 143.938 161.465 155.805 1.00 27.40  ? 504 SER C O   1 
ATOM   13159 C CB  . SER C 1 504 ? 142.748 163.785 157.634 1.00 22.38  ? 504 SER C CB  1 
ATOM   13160 O OG  . SER C 1 504 ? 141.718 164.684 157.908 1.00 35.72  ? 504 SER C OG  1 
ATOM   13161 N N   . LEU C 1 505 ? 143.782 160.838 157.941 1.00 18.08  ? 505 LEU C N   1 
ATOM   13162 C CA  . LEU C 1 505 ? 144.842 159.841 157.913 1.00 20.29  ? 505 LEU C CA  1 
ATOM   13163 C C   . LEU C 1 505 ? 144.482 158.646 157.020 1.00 18.80  ? 505 LEU C C   1 
ATOM   13164 O O   . LEU C 1 505 ? 145.265 158.292 156.145 1.00 26.87  ? 505 LEU C O   1 
ATOM   13165 C CB  . LEU C 1 505 ? 145.125 159.425 159.364 1.00 23.03  ? 505 LEU C CB  1 
ATOM   13166 C CG  . LEU C 1 505 ? 146.145 158.301 159.559 1.00 21.68  ? 505 LEU C CG  1 
ATOM   13167 C CD1 . LEU C 1 505 ? 147.559 158.780 159.279 1.00 15.78  ? 505 LEU C CD1 1 
ATOM   13168 C CD2 . LEU C 1 505 ? 146.059 157.817 161.000 1.00 18.06  ? 505 LEU C CD2 1 
ATOM   13169 N N   . VAL C 1 506 ? 143.297 158.054 157.190 1.00 19.36  ? 506 VAL C N   1 
ATOM   13170 C CA  . VAL C 1 506 ? 142.828 156.946 156.345 1.00 21.50  ? 506 VAL C CA  1 
ATOM   13171 C C   . VAL C 1 506 ? 142.759 157.391 154.891 1.00 18.10  ? 506 VAL C C   1 
ATOM   13172 O O   . VAL C 1 506 ? 143.349 156.763 154.018 1.00 22.74  ? 506 VAL C O   1 
ATOM   13173 C CB  . VAL C 1 506 ? 141.455 156.417 156.798 1.00 17.91  ? 506 VAL C CB  1 
ATOM   13174 C CG1 . VAL C 1 506 ? 140.896 155.347 155.861 1.00 21.90  ? 506 VAL C CG1 1 
ATOM   13175 C CG2 . VAL C 1 506 ? 141.536 155.783 158.174 1.00 18.27  ? 506 VAL C CG2 1 
ATOM   13176 N N   . LEU C 1 507 ? 142.096 158.518 154.632 1.00 17.51  ? 507 LEU C N   1 
ATOM   13177 C CA  . LEU C 1 507 ? 141.952 159.064 153.295 1.00 13.80  ? 507 LEU C CA  1 
ATOM   13178 C C   . LEU C 1 507 ? 143.306 159.403 152.653 1.00 8.21   ? 507 LEU C C   1 
ATOM   13179 O O   . LEU C 1 507 ? 143.496 159.176 151.470 1.00 30.62  ? 507 LEU C O   1 
ATOM   13180 C CB  . LEU C 1 507 ? 140.997 160.255 153.399 1.00 22.46  ? 507 LEU C CB  1 
ATOM   13181 C CG  . LEU C 1 507 ? 140.606 160.888 152.064 1.00 28.93  ? 507 LEU C CG  1 
ATOM   13182 C CD1 . LEU C 1 507 ? 139.944 159.911 151.105 1.00 28.20  ? 507 LEU C CD1 1 
ATOM   13183 C CD2 . LEU C 1 507 ? 139.624 162.016 152.335 1.00 27.25  ? 507 LEU C CD2 1 
ATOM   13184 N N   . GLY C 1 508 ? 144.290 159.848 153.433 1.00 7.75   ? 508 GLY C N   1 
ATOM   13185 C CA  . GLY C 1 508 ? 145.652 160.077 152.970 1.00 0.00   ? 508 GLY C CA  1 
ATOM   13186 C C   . GLY C 1 508 ? 146.433 158.819 152.603 1.00 9.08   ? 508 GLY C C   1 
ATOM   13187 O O   . GLY C 1 508 ? 147.203 158.840 151.650 1.00 22.83  ? 508 GLY C O   1 
ATOM   13188 N N   . TRP C 1 509 ? 146.224 157.686 153.267 1.00 22.55  ? 509 TRP C N   1 
ATOM   13189 C CA  . TRP C 1 509 ? 146.815 156.414 152.840 1.00 10.17  ? 509 TRP C CA  1 
ATOM   13190 C C   . TRP C 1 509 ? 146.168 155.864 151.568 1.00 10.41  ? 509 TRP C C   1 
ATOM   13191 O O   . TRP C 1 509 ? 146.869 155.387 150.691 1.00 23.34  ? 509 TRP C O   1 
ATOM   13192 C CB  . TRP C 1 509 ? 146.830 155.412 153.999 1.00 16.41  ? 509 TRP C CB  1 
ATOM   13193 C CG  . TRP C 1 509 ? 147.951 155.678 154.949 1.00 17.24  ? 509 TRP C CG  1 
ATOM   13194 C CD1 . TRP C 1 509 ? 147.853 156.239 156.171 1.00 16.52  ? 509 TRP C CD1 1 
ATOM   13195 C CD2 . TRP C 1 509 ? 149.380 155.482 154.720 1.00 26.27  ? 509 TRP C CD2 1 
ATOM   13196 N NE1 . TRP C 1 509 ? 149.117 156.445 156.680 1.00 17.42  ? 509 TRP C NE1 1 
ATOM   13197 C CE2 . TRP C 1 509 ? 150.096 156.041 155.813 1.00 23.38  ? 509 TRP C CE2 1 
ATOM   13198 C CE3 . TRP C 1 509 ? 150.150 154.902 153.687 1.00 28.04  ? 509 TRP C CE3 1 
ATOM   13199 C CZ2 . TRP C 1 509 ? 151.497 156.094 155.852 1.00 18.55  ? 509 TRP C CZ2 1 
ATOM   13200 C CZ3 . TRP C 1 509 ? 151.557 154.941 153.722 1.00 28.77  ? 509 TRP C CZ3 1 
ATOM   13201 C CH2 . TRP C 1 509 ? 152.232 155.562 154.785 1.00 24.48  ? 509 TRP C CH2 1 
ATOM   13202 N N   . LEU C 1 510 ? 144.847 155.991 151.453 1.00 16.98  ? 510 LEU C N   1 
ATOM   13203 C CA  . LEU C 1 510 ? 144.111 155.651 150.242 1.00 15.45  ? 510 LEU C CA  1 
ATOM   13204 C C   . LEU C 1 510 ? 144.545 156.526 149.060 1.00 17.71  ? 510 LEU C C   1 
ATOM   13205 O O   . LEU C 1 510 ? 144.672 156.029 147.948 1.00 31.40  ? 510 LEU C O   1 
ATOM   13206 C CB  . LEU C 1 510 ? 142.604 155.754 150.515 1.00 25.60  ? 510 LEU C CB  1 
ATOM   13207 C CG  . LEU C 1 510 ? 142.074 154.797 151.596 1.00 21.98  ? 510 LEU C CG  1 
ATOM   13208 C CD1 . LEU C 1 510 ? 140.596 155.050 151.834 1.00 17.29  ? 510 LEU C CD1 1 
ATOM   13209 C CD2 . LEU C 1 510 ? 142.271 153.341 151.219 1.00 22.35  ? 510 LEU C CD2 1 
ATOM   13210 N N   . ASN C 1 511 ? 144.863 157.796 149.296 1.00 16.52  ? 511 ASN C N   1 
ATOM   13211 C CA  . ASN C 1 511 ? 145.419 158.702 148.297 1.00 4.47   ? 511 ASN C CA  1 
ATOM   13212 C C   . ASN C 1 511 ? 146.780 158.273 147.744 1.00 4.09   ? 511 ASN C C   1 
ATOM   13213 O O   . ASN C 1 511 ? 147.041 158.534 146.576 1.00 29.61  ? 511 ASN C O   1 
ATOM   13214 C CB  . ASN C 1 511 ? 145.485 160.114 148.874 1.00 9.82   ? 511 ASN C CB  1 
ATOM   13215 C CG  . ASN C 1 511 ? 144.155 160.830 148.899 1.00 11.41  ? 511 ASN C CG  1 
ATOM   13216 O OD1 . ASN C 1 511 ? 143.166 160.394 148.341 1.00 21.80  ? 511 ASN C OD1 1 
ATOM   13217 N ND2 . ASN C 1 511 ? 144.097 161.984 149.508 1.00 8.75   ? 511 ASN C ND2 1 
ATOM   13218 N N   . LEU C 1 512 ? 147.631 157.563 148.488 1.00 14.32  ? 512 LEU C N   1 
ATOM   13219 C CA  . LEU C 1 512 ? 148.890 157.035 147.940 1.00 7.02   ? 512 LEU C CA  1 
ATOM   13220 C C   . LEU C 1 512 ? 148.684 156.041 146.792 1.00 13.89  ? 512 LEU C C   1 
ATOM   13221 O O   . LEU C 1 512 ? 149.584 155.866 145.978 1.00 19.91  ? 512 LEU C O   1 
ATOM   13222 C CB  . LEU C 1 512 ? 149.749 156.404 149.047 1.00 15.26  ? 512 LEU C CB  1 
ATOM   13223 C CG  . LEU C 1 512 ? 150.517 157.451 149.860 1.00 21.07  ? 512 LEU C CG  1 
ATOM   13224 C CD1 . LEU C 1 512 ? 150.831 156.928 151.246 1.00 32.24  ? 512 LEU C CD1 1 
ATOM   13225 C CD2 . LEU C 1 512 ? 151.844 157.804 149.198 1.00 15.70  ? 512 LEU C CD2 1 
ATOM   13226 N N   . LEU C 1 513 ? 147.504 155.436 146.657 1.00 13.74  ? 513 LEU C N   1 
ATOM   13227 C CA  . LEU C 1 513 ? 147.187 154.562 145.534 1.00 14.71  ? 513 LEU C CA  1 
ATOM   13228 C C   . LEU C 1 513 ? 147.111 155.292 144.189 1.00 14.48  ? 513 LEU C C   1 
ATOM   13229 O O   . LEU C 1 513 ? 147.233 154.634 143.161 1.00 28.09  ? 513 LEU C O   1 
ATOM   13230 C CB  . LEU C 1 513 ? 145.904 153.776 145.815 1.00 25.49  ? 513 LEU C CB  1 
ATOM   13231 C CG  . LEU C 1 513 ? 146.021 152.833 147.023 1.00 21.25  ? 513 LEU C CG  1 
ATOM   13232 C CD1 . LEU C 1 513 ? 144.637 152.320 147.385 1.00 19.06  ? 513 LEU C CD1 1 
ATOM   13233 C CD2 . LEU C 1 513 ? 146.935 151.646 146.726 1.00 12.81  ? 513 LEU C CD2 1 
ATOM   13234 N N   . TYR C 1 514 ? 147.012 156.624 144.175 1.00 14.47  ? 514 TYR C N   1 
ATOM   13235 C CA  . TYR C 1 514 ? 147.166 157.439 142.975 1.00 5.89   ? 514 TYR C CA  1 
ATOM   13236 C C   . TYR C 1 514 ? 148.489 157.153 142.252 1.00 11.67  ? 514 TYR C C   1 
ATOM   13237 O O   . TYR C 1 514 ? 148.511 156.926 141.047 1.00 30.46  ? 514 TYR C O   1 
ATOM   13238 C CB  . TYR C 1 514 ? 147.080 158.915 143.373 1.00 12.68  ? 514 TYR C CB  1 
ATOM   13239 C CG  . TYR C 1 514 ? 147.423 159.872 142.258 1.00 16.49  ? 514 TYR C CG  1 
ATOM   13240 C CD1 . TYR C 1 514 ? 146.471 160.194 141.278 1.00 12.12  ? 514 TYR C CD1 1 
ATOM   13241 C CD2 . TYR C 1 514 ? 148.730 160.378 142.162 1.00 15.27  ? 514 TYR C CD2 1 
ATOM   13242 C CE1 . TYR C 1 514 ? 146.838 161.011 140.194 1.00 11.45  ? 514 TYR C CE1 1 
ATOM   13243 C CE2 . TYR C 1 514 ? 149.108 161.174 141.074 1.00 6.72   ? 514 TYR C CE2 1 
ATOM   13244 C CZ  . TYR C 1 514 ? 148.159 161.484 140.081 1.00 11.98  ? 514 TYR C CZ  1 
ATOM   13245 O OH  . TYR C 1 514 ? 148.506 162.249 139.020 1.00 30.84  ? 514 TYR C OH  1 
ATOM   13246 N N   . TYR C 1 515 ? 149.598 157.107 142.990 1.00 21.80  ? 515 TYR C N   1 
ATOM   13247 C CA  . TYR C 1 515 ? 150.943 156.988 142.434 1.00 13.81  ? 515 TYR C CA  1 
ATOM   13248 C C   . TYR C 1 515 ? 151.267 155.604 141.874 1.00 9.76   ? 515 TYR C C   1 
ATOM   13249 O O   . TYR C 1 515 ? 152.290 155.424 141.227 1.00 21.92  ? 515 TYR C O   1 
ATOM   13250 C CB  . TYR C 1 515 ? 151.977 157.452 143.459 1.00 12.60  ? 515 TYR C CB  1 
ATOM   13251 C CG  . TYR C 1 515 ? 151.758 158.867 143.939 1.00 17.10  ? 515 TYR C CG  1 
ATOM   13252 C CD1 . TYR C 1 515 ? 152.241 159.962 143.198 1.00 15.80  ? 515 TYR C CD1 1 
ATOM   13253 C CD2 . TYR C 1 515 ? 151.049 159.084 145.132 1.00 7.40   ? 515 TYR C CD2 1 
ATOM   13254 C CE1 . TYR C 1 515 ? 152.022 161.275 143.653 1.00 11.60  ? 515 TYR C CE1 1 
ATOM   13255 C CE2 . TYR C 1 515 ? 150.833 160.389 145.589 1.00 13.61  ? 515 TYR C CE2 1 
ATOM   13256 C CZ  . TYR C 1 515 ? 151.315 161.486 144.852 1.00 15.97  ? 515 TYR C CZ  1 
ATOM   13257 O OH  . TYR C 1 515 ? 151.074 162.732 145.315 1.00 20.50  ? 515 TYR C OH  1 
ATOM   13258 N N   . THR C 1 516 ? 150.362 154.633 142.001 1.00 10.98  ? 516 THR C N   1 
ATOM   13259 C CA  . THR C 1 516 ? 150.505 153.332 141.336 1.00 17.12  ? 516 THR C CA  1 
ATOM   13260 C C   . THR C 1 516 ? 150.562 153.448 139.813 1.00 21.82  ? 516 THR C C   1 
ATOM   13261 O O   . THR C 1 516 ? 151.161 152.580 139.187 1.00 37.61  ? 516 THR C O   1 
ATOM   13262 C CB  . THR C 1 516 ? 149.406 152.341 141.732 1.00 22.25  ? 516 THR C CB  1 
ATOM   13263 O OG1 . THR C 1 516 ? 148.134 152.795 141.359 1.00 31.57  ? 516 THR C OG1 1 
ATOM   13264 C CG2 . THR C 1 516 ? 149.411 151.998 143.212 1.00 11.50  ? 516 THR C CG2 1 
ATOM   13265 N N   . ARG C 1 517 ? 150.039 154.524 139.208 1.00 17.60  ? 517 ARG C N   1 
ATOM   13266 C CA  . ARG C 1 517 ? 150.144 154.835 137.768 1.00 9.33   ? 517 ARG C CA  1 
ATOM   13267 C C   . ARG C 1 517 ? 151.554 155.157 137.261 1.00 18.53  ? 517 ARG C C   1 
ATOM   13268 O O   . ARG C 1 517 ? 151.761 155.162 136.051 1.00 32.44  ? 517 ARG C O   1 
ATOM   13269 C CB  . ARG C 1 517 ? 149.144 155.941 137.407 1.00 17.52  ? 517 ARG C CB  1 
ATOM   13270 C CG  . ARG C 1 517 ? 149.552 157.336 137.907 1.00 19.87  ? 517 ARG C CG  1 
ATOM   13271 C CD  . ARG C 1 517 ? 148.437 158.368 137.802 1.00 5.49   ? 517 ARG C CD  1 
ATOM   13272 N NE  . ARG C 1 517 ? 147.255 157.932 138.560 1.00 19.08  ? 517 ARG C NE  1 
ATOM   13273 C CZ  . ARG C 1 517 ? 145.998 158.166 138.266 1.00 17.22  ? 517 ARG C CZ  1 
ATOM   13274 N NH1 . ARG C 1 517 ? 145.052 157.497 138.838 1.00 12.05  ? 517 ARG C NH1 1 
ATOM   13275 N NH2 . ARG C 1 517 ? 145.657 159.060 137.390 1.00 24.62  ? 517 ARG C NH2 1 
ATOM   13276 N N   . GLY C 1 518 ? 152.526 155.394 138.141 1.00 27.90  ? 518 GLY C N   1 
ATOM   13277 C CA  . GLY C 1 518 ? 153.910 155.680 137.766 1.00 21.23  ? 518 GLY C CA  1 
ATOM   13278 C C   . GLY C 1 518 ? 154.664 154.497 137.158 1.00 21.86  ? 518 GLY C C   1 
ATOM   13279 O O   . GLY C 1 518 ? 155.611 154.704 136.405 1.00 39.14  ? 518 GLY C O   1 
ATOM   13280 N N   . PHE C 1 519 ? 154.234 153.268 137.432 1.00 10.80  ? 519 PHE C N   1 
ATOM   13281 C CA  . PHE C 1 519 ? 154.825 152.045 136.894 1.00 21.77  ? 519 PHE C CA  1 
ATOM   13282 C C   . PHE C 1 519 ? 153.813 151.299 136.042 1.00 28.02  ? 519 PHE C C   1 
ATOM   13283 O O   . PHE C 1 519 ? 152.640 151.238 136.395 1.00 31.45  ? 519 PHE C O   1 
ATOM   13284 C CB  . PHE C 1 519 ? 155.313 151.129 138.021 1.00 25.26  ? 519 PHE C CB  1 
ATOM   13285 C CG  . PHE C 1 519 ? 156.282 151.767 138.988 1.00 24.89  ? 519 PHE C CG  1 
ATOM   13286 C CD1 . PHE C 1 519 ? 157.609 152.004 138.594 1.00 23.56  ? 519 PHE C CD1 1 
ATOM   13287 C CD2 . PHE C 1 519 ? 155.858 152.115 140.279 1.00 25.48  ? 519 PHE C CD2 1 
ATOM   13288 C CE1 . PHE C 1 519 ? 158.514 152.586 139.494 1.00 27.79  ? 519 PHE C CE1 1 
ATOM   13289 C CE2 . PHE C 1 519 ? 156.766 152.685 141.182 1.00 32.69  ? 519 PHE C CE2 1 
ATOM   13290 C CZ  . PHE C 1 519 ? 158.094 152.919 140.790 1.00 29.14  ? 519 PHE C CZ  1 
ATOM   13291 N N   . GLN C 1 520 ? 154.252 150.681 134.953 1.00 40.23  ? 520 GLN C N   1 
ATOM   13292 C CA  . GLN C 1 520 ? 153.363 149.924 134.073 1.00 34.08  ? 520 GLN C CA  1 
ATOM   13293 C C   . GLN C 1 520 ? 152.681 148.763 134.794 1.00 35.19  ? 520 GLN C C   1 
ATOM   13294 O O   . GLN C 1 520 ? 151.482 148.562 134.647 1.00 35.74  ? 520 GLN C O   1 
ATOM   13295 C CB  . GLN C 1 520 ? 154.172 149.456 132.858 1.00 33.61  ? 520 GLN C CB  1 
ATOM   13296 C CG  . GLN C 1 520 ? 153.287 148.776 131.810 1.00 35.52  ? 520 GLN C CG  1 
ATOM   13297 C CD  . GLN C 1 520 ? 153.961 148.598 130.452 1.00 39.99  ? 520 GLN C CD  1 
ATOM   13298 O OE1 . GLN C 1 520 ? 154.830 149.348 130.035 1.00 43.46  ? 520 GLN C OE1 1 
ATOM   13299 N NE2 . GLN C 1 520 ? 153.577 147.598 129.700 1.00 43.24  ? 520 GLN C NE2 1 
ATOM   13300 N N   . HIS C 1 521 ? 153.426 148.028 135.621 1.00 38.54  ? 521 HIS C N   1 
ATOM   13301 C CA  . HIS C 1 521 ? 152.946 146.821 136.292 1.00 36.47  ? 521 HIS C CA  1 
ATOM   13302 C C   . HIS C 1 521 ? 151.807 147.109 137.276 1.00 35.33  ? 521 HIS C C   1 
ATOM   13303 O O   . HIS C 1 521 ? 150.733 146.506 137.106 1.00 37.80  ? 521 HIS C O   1 
ATOM   13304 C CB  . HIS C 1 521 ? 154.095 146.095 137.007 1.00 36.51  ? 521 HIS C CB  1 
ATOM   13305 C CG  . HIS C 1 521 ? 153.735 144.707 137.418 1.00 42.93  ? 521 HIS C CG  1 
ATOM   13306 N ND1 . HIS C 1 521 ? 154.055 144.194 138.661 1.00 45.28  ? 521 HIS C ND1 1 
ATOM   13307 C CD2 . HIS C 1 521 ? 153.074 143.727 136.764 1.00 37.78  ? 521 HIS C CD2 1 
ATOM   13308 C CE1 . HIS C 1 521 ? 153.614 142.955 138.750 1.00 44.11  ? 521 HIS C CE1 1 
ATOM   13309 N NE2 . HIS C 1 521 ? 153.007 142.645 137.599 1.00 44.67  ? 521 HIS C NE2 1 
ATOM   13310 N N   . THR C 1 522 ? 151.997 148.032 138.222 1.00 34.79  ? 522 THR C N   1 
ATOM   13311 C CA  . THR C 1 522 ? 150.918 148.411 139.173 1.00 32.05  ? 522 THR C CA  1 
ATOM   13312 C C   . THR C 1 522 ? 149.880 149.277 138.451 1.00 32.05  ? 522 THR C C   1 
ATOM   13313 O O   . THR C 1 522 ? 148.675 149.005 138.616 1.00 25.81  ? 522 THR C O   1 
ATOM   13314 C CB  . THR C 1 522 ? 151.494 149.136 140.396 1.00 33.41  ? 522 THR C CB  1 
ATOM   13315 O OG1 . THR C 1 522 ? 152.151 150.318 139.938 1.00 32.17  ? 522 THR C OG1 1 
ATOM   13316 C CG2 . THR C 1 522 ? 152.467 148.282 141.179 1.00 26.45  ? 522 THR C CG2 1 
ATOM   13317 N N   . GLY C 1 523 ? 150.336 150.274 137.685 1.00 36.86  ? 523 GLY C N   1 
ATOM   13318 C CA  . GLY C 1 523 ? 149.414 151.169 136.959 1.00 24.07  ? 523 GLY C CA  1 
ATOM   13319 C C   . GLY C 1 523 ? 148.323 150.396 136.241 1.00 31.16  ? 523 GLY C C   1 
ATOM   13320 O O   . GLY C 1 523 ? 147.145 150.549 136.621 1.00 49.85  ? 523 GLY C O   1 
ATOM   13321 N N   . ILE C 1 524 ? 148.697 149.593 135.241 1.00 29.92  ? 524 ILE C N   1 
ATOM   13322 C CA  . ILE C 1 524 ? 147.713 148.817 134.478 1.00 31.74  ? 524 ILE C CA  1 
ATOM   13323 C C   . ILE C 1 524 ? 146.830 147.979 135.415 1.00 41.79  ? 524 ILE C C   1 
ATOM   13324 O O   . ILE C 1 524 ? 145.626 147.877 135.179 1.00 42.74  ? 524 ILE C O   1 
ATOM   13325 C CB  . ILE C 1 524 ? 148.437 147.974 133.408 1.00 41.04  ? 524 ILE C CB  1 
ATOM   13326 C CG1 . ILE C 1 524 ? 149.040 148.925 132.353 1.00 34.90  ? 524 ILE C CG1 1 
ATOM   13327 C CG2 . ILE C 1 524 ? 147.502 146.963 132.734 1.00 35.45  ? 524 ILE C CG2 1 
ATOM   13328 C CD1 . ILE C 1 524 ? 149.817 148.227 131.244 1.00 31.89  ? 524 ILE C CD1 1 
ATOM   13329 N N   . TYR C 1 525 ? 147.360 147.427 136.511 1.00 37.19  ? 525 TYR C N   1 
ATOM   13330 C CA  . TYR C 1 525 ? 146.528 146.676 137.455 1.00 33.71  ? 525 TYR C CA  1 
ATOM   13331 C C   . TYR C 1 525 ? 145.505 147.551 138.177 1.00 37.89  ? 525 TYR C C   1 
ATOM   13332 O O   . TYR C 1 525 ? 144.342 147.173 138.296 1.00 44.93  ? 525 TYR C O   1 
ATOM   13333 C CB  . TYR C 1 525 ? 147.386 145.918 138.458 1.00 40.27  ? 525 TYR C CB  1 
ATOM   13334 C CG  . TYR C 1 525 ? 146.592 144.872 139.208 1.00 34.78  ? 525 TYR C CG  1 
ATOM   13335 C CD1 . TYR C 1 525 ? 146.127 143.744 138.511 1.00 31.38  ? 525 TYR C CD1 1 
ATOM   13336 C CD2 . TYR C 1 525 ? 146.251 145.056 140.561 1.00 32.65  ? 525 TYR C CD2 1 
ATOM   13337 C CE1 . TYR C 1 525 ? 145.338 142.784 139.161 1.00 43.21  ? 525 TYR C CE1 1 
ATOM   13338 C CE2 . TYR C 1 525 ? 145.456 144.096 141.213 1.00 41.04  ? 525 TYR C CE2 1 
ATOM   13339 C CZ  . TYR C 1 525 ? 144.999 142.956 140.518 1.00 43.96  ? 525 TYR C CZ  1 
ATOM   13340 O OH  . TYR C 1 525 ? 144.209 142.046 141.141 1.00 32.72  ? 525 TYR C OH  1 
ATOM   13341 N N   . SER C 1 526 ? 145.885 148.759 138.577 1.00 26.86  ? 526 SER C N   1 
ATOM   13342 C CA  . SER C 1 526 ? 144.948 149.752 139.096 1.00 34.60  ? 526 SER C CA  1 
ATOM   13343 C C   . SER C 1 526 ? 143.784 150.042 138.134 1.00 39.72  ? 526 SER C C   1 
ATOM   13344 O O   . SER C 1 526 ? 142.664 150.247 138.589 1.00 48.34  ? 526 SER C O   1 
ATOM   13345 C CB  . SER C 1 526 ? 145.728 151.015 139.441 1.00 40.06  ? 526 SER C CB  1 
ATOM   13346 O OG  . SER C 1 526 ? 146.404 150.813 140.661 1.00 46.67  ? 526 SER C OG  1 
ATOM   13347 N N   . VAL C 1 527 ? 143.995 149.934 136.820 1.00 39.54  ? 527 VAL C N   1 
ATOM   13348 C CA  . VAL C 1 527 ? 142.941 150.014 135.799 1.00 40.11  ? 527 VAL C CA  1 
ATOM   13349 C C   . VAL C 1 527 ? 142.116 148.724 135.667 1.00 40.47  ? 527 VAL C C   1 
ATOM   13350 O O   . VAL C 1 527 ? 140.893 148.787 135.607 1.00 42.00  ? 527 VAL C O   1 
ATOM   13351 C CB  . VAL C 1 527 ? 143.552 150.407 134.445 1.00 40.79  ? 527 VAL C CB  1 
ATOM   13352 C CG1 . VAL C 1 527 ? 142.513 150.379 133.336 1.00 42.41  ? 527 VAL C CG1 1 
ATOM   13353 C CG2 . VAL C 1 527 ? 144.135 151.817 134.483 1.00 35.77  ? 527 VAL C CG2 1 
ATOM   13354 N N   . MET C 1 528 ? 142.744 147.545 135.667 1.00 47.86  ? 528 MET C N   1 
ATOM   13355 C CA  . MET C 1 528 ? 142.042 146.248 135.678 1.00 47.15  ? 528 MET C CA  1 
ATOM   13356 C C   . MET C 1 528 ? 141.099 146.108 136.888 1.00 48.01  ? 528 MET C C   1 
ATOM   13357 O O   . MET C 1 528 ? 139.988 145.603 136.770 1.00 49.95  ? 528 MET C O   1 
ATOM   13358 C CB  . MET C 1 528 ? 143.069 145.107 135.703 1.00 47.41  ? 528 MET C CB  1 
ATOM   13359 C CG  . MET C 1 528 ? 143.901 145.013 134.423 1.00 49.07  ? 528 MET C CG  1 
ATOM   13360 S SD  . MET C 1 528 ? 145.361 143.954 134.613 1.00 66.06  ? 528 MET C SD  1 
ATOM   13361 C CE  . MET C 1 528 ? 145.656 143.552 132.873 1.00 50.00  ? 528 MET C CE  1 
ATOM   13362 N N   . ILE C 1 529 ? 141.513 146.623 138.043 1.00 51.56  ? 529 ILE C N   1 
ATOM   13363 C CA  . ILE C 1 529 ? 140.722 146.610 139.319 1.00 51.31  ? 529 ILE C CA  1 
ATOM   13364 C C   . ILE C 1 529 ? 139.554 147.614 139.316 1.00 51.87  ? 529 ILE C C   1 
ATOM   13365 O O   . ILE C 1 529 ? 138.806 147.632 140.284 1.00 60.31  ? 529 ILE C O   1 
ATOM   13366 C CB  . ILE C 1 529 ? 141.653 146.846 140.525 1.00 52.74  ? 529 ILE C CB  1 
ATOM   13367 C CG1 . ILE C 1 529 ? 142.586 145.655 140.752 1.00 54.40  ? 529 ILE C CG1 1 
ATOM   13368 C CG2 . ILE C 1 529 ? 140.847 147.174 141.773 1.00 53.01  ? 529 ILE C CG2 1 
ATOM   13369 C CD1 . ILE C 1 529 ? 141.861 144.347 140.966 1.00 46.50  ? 529 ILE C CD1 1 
ATOM   13370 N N   . GLN C 1 530 ? 139.279 148.374 138.253 1.00 47.24  ? 530 GLN C N   1 
ATOM   13371 C CA  . GLN C 1 530 ? 138.051 149.184 138.146 1.00 41.59  ? 530 GLN C CA  1 
ATOM   13372 C C   . GLN C 1 530 ? 136.815 148.407 137.641 1.00 45.96  ? 530 GLN C C   1 
ATOM   13373 O O   . GLN C 1 530 ? 135.733 148.985 137.620 1.00 48.08  ? 530 GLN C O   1 
ATOM   13374 C CB  . GLN C 1 530 ? 138.283 150.400 137.236 1.00 51.71  ? 530 GLN C CB  1 
ATOM   13375 C CG  . GLN C 1 530 ? 139.500 151.263 137.580 1.00 53.26  ? 530 GLN C CG  1 
ATOM   13376 C CD  . GLN C 1 530 ? 139.463 151.847 138.981 1.00 50.21  ? 530 GLN C CD  1 
ATOM   13377 O OE1 . GLN C 1 530 ? 138.546 152.549 139.373 1.00 57.01  ? 530 GLN C OE1 1 
ATOM   13378 N NE2 . GLN C 1 530 ? 140.494 151.635 139.759 1.00 48.20  ? 530 GLN C NE2 1 
ATOM   13379 N N   . LYS C 1 531 ? 136.937 147.143 137.203 1.00 47.06  ? 531 LYS C N   1 
ATOM   13380 C CA  . LYS C 1 531 ? 135.892 146.340 136.519 1.00 46.17  ? 531 LYS C CA  1 
ATOM   13381 C C   . LYS C 1 531 ? 134.470 146.549 137.048 1.00 49.37  ? 531 LYS C C   1 
ATOM   13382 O O   . LYS C 1 531 ? 133.560 146.869 136.289 1.00 51.03  ? 531 LYS C O   1 
ATOM   13383 C CB  . LYS C 1 531 ? 136.246 144.834 136.633 1.00 46.33  ? 531 LYS C CB  1 
ATOM   13384 C CG  . LYS C 1 531 ? 137.132 144.288 135.507 1.00 46.96  ? 531 LYS C CG  1 
ATOM   13385 C CD  . LYS C 1 531 ? 136.342 144.018 134.222 1.00 48.94  ? 531 LYS C CD  1 
ATOM   13386 C CE  . LYS C 1 531 ? 137.236 143.345 133.174 1.00 52.22  ? 531 LYS C CE  1 
ATOM   13387 N NZ  . LYS C 1 531 ? 136.498 143.036 131.918 1.00 52.14  ? 531 LYS C NZ  1 
ATOM   13388 N N   . VAL C 1 532 ? 134.274 146.324 138.342 1.00 54.32  ? 532 VAL C N   1 
ATOM   13389 C CA  . VAL C 1 532 ? 133.004 146.430 139.066 1.00 49.39  ? 532 VAL C CA  1 
ATOM   13390 C C   . VAL C 1 532 ? 132.844 147.867 139.554 1.00 54.18  ? 532 VAL C C   1 
ATOM   13391 O O   . VAL C 1 532 ? 133.323 148.259 140.620 1.00 57.59  ? 532 VAL C O   1 
ATOM   13392 C CB  . VAL C 1 532 ? 132.945 145.400 140.209 1.00 50.48  ? 532 VAL C CB  1 
ATOM   13393 C CG1 . VAL C 1 532 ? 131.626 145.493 140.971 1.00 51.39  ? 532 VAL C CG1 1 
ATOM   13394 C CG2 . VAL C 1 532 ? 133.094 143.976 139.656 1.00 49.75  ? 532 VAL C CG2 1 
ATOM   13395 N N   . ILE C 1 533 ? 132.194 148.680 138.724 1.00 59.56  ? 533 ILE C N   1 
ATOM   13396 C CA  . ILE C 1 533 ? 131.883 150.082 139.013 1.00 58.40  ? 533 ILE C CA  1 
ATOM   13397 C C   . ILE C 1 533 ? 130.874 150.140 140.175 1.00 51.11  ? 533 ILE C C   1 
ATOM   13398 O O   . ILE C 1 533 ? 130.107 149.202 140.399 1.00 49.52  ? 533 ILE C O   1 
ATOM   13399 C CB  . ILE C 1 533 ? 131.355 150.775 137.721 1.00 53.51  ? 533 ILE C CB  1 
ATOM   13400 C CG1 . ILE C 1 533 ? 132.254 150.545 136.482 1.00 50.59  ? 533 ILE C CG1 1 
ATOM   13401 C CG2 . ILE C 1 533 ? 131.156 152.294 137.875 1.00 52.75  ? 533 ILE C CG2 1 
ATOM   13402 C CD1 . ILE C 1 533 ? 133.636 151.197 136.555 1.00 48.41  ? 533 ILE C CD1 1 
ATOM   13403 N N   . LEU C 1 534 ? 130.769 151.275 140.864 1.00 46.49  ? 534 LEU C N   1 
ATOM   13404 C CA  . LEU C 1 534 ? 129.629 151.541 141.750 1.00 47.81  ? 534 LEU C CA  1 
ATOM   13405 C C   . LEU C 1 534 ? 128.269 151.485 141.032 1.00 49.02  ? 534 LEU C C   1 
ATOM   13406 O O   . LEU C 1 534 ? 127.253 151.416 141.702 1.00 55.50  ? 534 LEU C O   1 
ATOM   13407 C CB  . LEU C 1 534 ? 129.803 152.898 142.455 1.00 52.10  ? 534 LEU C CB  1 
ATOM   13408 C CG  . LEU C 1 534 ? 131.032 153.004 143.371 1.00 54.72  ? 534 LEU C CG  1 
ATOM   13409 C CD1 . LEU C 1 534 ? 131.100 154.418 143.941 1.00 53.65  ? 534 LEU C CD1 1 
ATOM   13410 C CD2 . LEU C 1 534 ? 130.976 152.008 144.527 1.00 52.05  ? 534 LEU C CD2 1 
ATOM   13411 N N   . ARG C 1 535 ? 128.262 151.455 139.694 1.00 47.02  ? 535 ARG C N   1 
ATOM   13412 C CA  . ARG C 1 535 ? 127.003 151.412 138.887 1.00 47.10  ? 535 ARG C CA  1 
ATOM   13413 C C   . ARG C 1 535 ? 126.094 150.274 139.365 1.00 47.08  ? 535 ARG C C   1 
ATOM   13414 O O   . ARG C 1 535 ? 124.895 150.537 139.584 1.00 48.92  ? 535 ARG C O   1 
ATOM   13415 C CB  . ARG C 1 535 ? 127.405 151.269 137.411 1.00 49.32  ? 535 ARG C CB  1 
ATOM   13416 C CG  . ARG C 1 535 ? 126.234 151.464 136.437 1.00 47.93  ? 535 ARG C CG  1 
ATOM   13417 C CD  . ARG C 1 535 ? 126.522 150.800 135.092 1.00 47.60  ? 535 ARG C CD  1 
ATOM   13418 N NE  . ARG C 1 535 ? 126.595 149.353 135.243 1.00 50.84  ? 535 ARG C NE  1 
ATOM   13419 C CZ  . ARG C 1 535 ? 126.773 148.494 134.246 1.00 51.33  ? 535 ARG C CZ  1 
ATOM   13420 N NH1 . ARG C 1 535 ? 126.823 147.197 134.494 1.00 45.90  ? 535 ARG C NH1 1 
ATOM   13421 N NH2 . ARG C 1 535 ? 126.898 148.935 133.007 1.00 49.27  ? 535 ARG C NH2 1 
ATOM   13422 N N   . ASP C 1 536 ? 126.640 149.065 139.517 1.00 41.47  ? 536 ASP C N   1 
ATOM   13423 C CA  . ASP C 1 536 ? 125.840 147.906 139.926 1.00 37.39  ? 536 ASP C CA  1 
ATOM   13424 C C   . ASP C 1 536 ? 125.782 147.746 141.440 1.00 40.90  ? 536 ASP C C   1 
ATOM   13425 O O   . ASP C 1 536 ? 124.712 147.505 141.982 1.00 46.81  ? 536 ASP C O   1 
ATOM   13426 C CB  . ASP C 1 536 ? 126.297 146.633 139.212 1.00 40.80  ? 536 ASP C CB  1 
ATOM   13427 C CG  . ASP C 1 536 ? 125.996 146.664 137.707 1.00 46.75  ? 536 ASP C CG  1 
ATOM   13428 O OD1 . ASP C 1 536 ? 125.446 147.673 137.214 1.00 46.54  ? 536 ASP C OD1 1 
ATOM   13429 O OD2 . ASP C 1 536 ? 126.314 145.700 136.989 1.00 47.40  ? 536 ASP C OD2 1 
ATOM   13430 N N   . LEU C 1 537 ? 126.880 147.957 142.162 1.00 39.50  ? 537 LEU C N   1 
ATOM   13431 C CA  . LEU C 1 537 ? 126.873 147.828 143.617 1.00 33.77  ? 537 LEU C CA  1 
ATOM   13432 C C   . LEU C 1 537 ? 126.018 148.886 144.322 1.00 40.21  ? 537 LEU C C   1 
ATOM   13433 O O   . LEU C 1 537 ? 125.388 148.551 145.314 1.00 49.38  ? 537 LEU C O   1 
ATOM   13434 C CB  . LEU C 1 537 ? 128.311 147.762 144.153 1.00 36.89  ? 537 LEU C CB  1 
ATOM   13435 C CG  . LEU C 1 537 ? 128.716 146.311 144.430 1.00 41.91  ? 537 LEU C CG  1 
ATOM   13436 C CD1 . LEU C 1 537 ? 128.671 145.424 143.192 1.00 41.74  ? 537 LEU C CD1 1 
ATOM   13437 C CD2 . LEU C 1 537 ? 130.121 146.275 145.000 1.00 44.21  ? 537 LEU C CD2 1 
ATOM   13438 N N   . LEU C 1 538 ? 125.893 150.113 143.809 1.00 40.83  ? 538 LEU C N   1 
ATOM   13439 C CA  . LEU C 1 538 ? 124.962 151.110 144.347 1.00 43.94  ? 538 LEU C CA  1 
ATOM   13440 C C   . LEU C 1 538 ? 123.489 150.753 144.076 1.00 40.94  ? 538 LEU C C   1 
ATOM   13441 O O   . LEU C 1 538 ? 122.608 151.114 144.851 1.00 45.46  ? 538 LEU C O   1 
ATOM   13442 C CB  . LEU C 1 538 ? 125.337 152.493 143.775 1.00 44.76  ? 538 LEU C CB  1 
ATOM   13443 C CG  . LEU C 1 538 ? 124.555 153.694 144.319 1.00 46.80  ? 538 LEU C CG  1 
ATOM   13444 C CD1 . LEU C 1 538 ? 124.691 153.854 145.823 1.00 43.12  ? 538 LEU C CD1 1 
ATOM   13445 C CD2 . LEU C 1 538 ? 125.074 154.964 143.664 1.00 43.33  ? 538 LEU C CD2 1 
ATOM   13446 N N   . ARG C 1 539 ? 123.248 149.975 143.007 1.00 32.43  ? 539 ARG C N   1 
ATOM   13447 C CA  . ARG C 1 539 ? 121.863 149.510 142.679 1.00 30.20  ? 539 ARG C CA  1 
ATOM   13448 C C   . ARG C 1 539 ? 121.546 148.308 143.579 1.00 34.69  ? 539 ARG C C   1 
ATOM   13449 O O   . ARG C 1 539 ? 120.469 148.320 144.207 1.00 46.82  ? 539 ARG C O   1 
ATOM   13450 C CB  . ARG C 1 539 ? 121.729 149.347 141.162 1.00 41.51  ? 539 ARG C CB  1 
ATOM   13451 C CG  . ARG C 1 539 ? 121.807 150.688 140.426 1.00 42.33  ? 539 ARG C CG  1 
ATOM   13452 C CD  . ARG C 1 539 ? 121.414 150.544 138.956 1.00 38.32  ? 539 ARG C CD  1 
ATOM   13453 N NE  . ARG C 1 539 ? 122.333 149.677 138.233 1.00 40.36  ? 539 ARG C NE  1 
ATOM   13454 C CZ  . ARG C 1 539 ? 122.259 149.417 136.932 1.00 41.43  ? 539 ARG C CZ  1 
ATOM   13455 N NH1 . ARG C 1 539 ? 123.143 148.614 136.366 1.00 39.17  ? 539 ARG C NH1 1 
ATOM   13456 N NH2 . ARG C 1 539 ? 121.303 149.963 136.202 1.00 36.79  ? 539 ARG C NH2 1 
ATOM   13457 N N   . PHE C 1 540 ? 122.441 147.323 143.652 1.00 36.16  ? 540 PHE C N   1 
ATOM   13458 C CA  . PHE C 1 540 ? 122.311 146.198 144.584 1.00 31.41  ? 540 PHE C CA  1 
ATOM   13459 C C   . PHE C 1 540 ? 122.122 146.691 146.020 1.00 25.90  ? 540 PHE C C   1 
ATOM   13460 O O   . PHE C 1 540 ? 121.281 146.160 146.741 1.00 28.93  ? 540 PHE C O   1 
ATOM   13461 C CB  . PHE C 1 540 ? 123.541 145.285 144.454 1.00 31.28  ? 540 PHE C CB  1 
ATOM   13462 C CG  . PHE C 1 540 ? 123.948 144.573 145.729 1.00 38.71  ? 540 PHE C CG  1 
ATOM   13463 C CD1 . PHE C 1 540 ? 123.303 143.387 146.133 1.00 36.41  ? 540 PHE C CD1 1 
ATOM   13464 C CD2 . PHE C 1 540 ? 124.948 145.133 146.547 1.00 35.25  ? 540 PHE C CD2 1 
ATOM   13465 C CE1 . PHE C 1 540 ? 123.647 142.782 147.350 1.00 27.55  ? 540 PHE C CE1 1 
ATOM   13466 C CE2 . PHE C 1 540 ? 125.269 144.545 147.776 1.00 32.86  ? 540 PHE C CE2 1 
ATOM   13467 C CZ  . PHE C 1 540 ? 124.617 143.369 148.176 1.00 33.03  ? 540 PHE C CZ  1 
ATOM   13468 N N   . LEU C 1 541 ? 122.844 147.738 146.421 1.00 19.20  ? 541 LEU C N   1 
ATOM   13469 C CA  . LEU C 1 541 ? 122.748 148.323 147.746 1.00 28.68  ? 541 LEU C CA  1 
ATOM   13470 C C   . LEU C 1 541 ? 121.337 148.814 148.068 1.00 29.19  ? 541 LEU C C   1 
ATOM   13471 O O   . LEU C 1 541 ? 120.877 148.610 149.179 1.00 37.90  ? 541 LEU C O   1 
ATOM   13472 C CB  . LEU C 1 541 ? 123.793 149.444 147.868 1.00 33.04  ? 541 LEU C CB  1 
ATOM   13473 C CG  . LEU C 1 541 ? 123.860 150.113 149.246 1.00 32.91  ? 541 LEU C CG  1 
ATOM   13474 C CD1 . LEU C 1 541 ? 124.400 149.159 150.310 1.00 30.39  ? 541 LEU C CD1 1 
ATOM   13475 C CD2 . LEU C 1 541 ? 124.782 151.320 149.168 1.00 32.93  ? 541 LEU C CD2 1 
ATOM   13476 N N   . LEU C 1 542 ? 120.604 149.384 147.108 1.00 26.34  ? 542 LEU C N   1 
ATOM   13477 C CA  . LEU C 1 542 ? 119.206 149.758 147.298 1.00 22.34  ? 542 LEU C CA  1 
ATOM   13478 C C   . LEU C 1 542 ? 118.333 148.559 147.693 1.00 20.49  ? 542 LEU C C   1 
ATOM   13479 O O   . LEU C 1 542 ? 117.605 148.621 148.676 1.00 32.24  ? 542 LEU C O   1 
ATOM   13480 C CB  . LEU C 1 542 ? 118.708 150.450 146.015 1.00 28.65  ? 542 LEU C CB  1 
ATOM   13481 C CG  . LEU C 1 542 ? 117.229 150.871 146.033 1.00 29.21  ? 542 LEU C CG  1 
ATOM   13482 C CD1 . LEU C 1 542 ? 116.941 151.933 147.085 1.00 31.51  ? 542 LEU C CD1 1 
ATOM   13483 C CD2 . LEU C 1 542 ? 116.851 151.435 144.673 1.00 23.63  ? 542 LEU C CD2 1 
ATOM   13484 N N   . VAL C 1 543 ? 118.438 147.442 146.975 1.00 21.26  ? 543 VAL C N   1 
ATOM   13485 C CA  . VAL C 1 543 ? 117.692 146.217 147.294 1.00 19.67  ? 543 VAL C CA  1 
ATOM   13486 C C   . VAL C 1 543 ? 118.133 145.630 148.631 1.00 21.93  ? 543 VAL C C   1 
ATOM   13487 O O   . VAL C 1 543 ? 117.298 145.307 149.473 1.00 30.93  ? 543 VAL C O   1 
ATOM   13488 C CB  . VAL C 1 543 ? 117.826 145.172 146.170 1.00 22.11  ? 543 VAL C CB  1 
ATOM   13489 C CG1 . VAL C 1 543 ? 116.994 143.926 146.459 1.00 20.68  ? 543 VAL C CG1 1 
ATOM   13490 C CG2 . VAL C 1 543 ? 117.356 145.757 144.840 1.00 24.61  ? 543 VAL C CG2 1 
ATOM   13491 N N   . TYR C 1 544 ? 119.442 145.544 148.857 1.00 29.66  ? 544 TYR C N   1 
ATOM   13492 C CA  . TYR C 1 544 ? 120.007 145.032 150.091 1.00 11.40  ? 544 TYR C CA  1 
ATOM   13493 C C   . TYR C 1 544 ? 119.613 145.855 151.325 1.00 14.48  ? 544 TYR C C   1 
ATOM   13494 O O   . TYR C 1 544 ? 119.281 145.276 152.350 1.00 29.68  ? 544 TYR C O   1 
ATOM   13495 C CB  . TYR C 1 544 ? 121.526 144.890 149.971 1.00 19.05  ? 544 TYR C CB  1 
ATOM   13496 C CG  . TYR C 1 544 ? 122.151 144.416 151.255 1.00 30.63  ? 544 TYR C CG  1 
ATOM   13497 C CD1 . TYR C 1 544 ? 122.095 143.083 151.618 1.00 25.03  ? 544 TYR C CD1 1 
ATOM   13498 C CD2 . TYR C 1 544 ? 122.735 145.307 152.136 1.00 23.56  ? 544 TYR C CD2 1 
ATOM   13499 C CE1 . TYR C 1 544 ? 122.630 142.641 152.813 1.00 22.27  ? 544 TYR C CE1 1 
ATOM   13500 C CE2 . TYR C 1 544 ? 123.271 144.882 153.338 1.00 16.54  ? 544 TYR C CE2 1 
ATOM   13501 C CZ  . TYR C 1 544 ? 123.224 143.544 153.673 1.00 28.73  ? 544 TYR C CZ  1 
ATOM   13502 O OH  . TYR C 1 544 ? 123.758 143.114 154.849 1.00 39.08  ? 544 TYR C OH  1 
ATOM   13503 N N   . LEU C 1 545 ? 119.608 147.186 151.259 1.00 10.84  ? 545 LEU C N   1 
ATOM   13504 C CA  . LEU C 1 545 ? 119.222 148.025 152.394 1.00 16.93  ? 545 LEU C CA  1 
ATOM   13505 C C   . LEU C 1 545 ? 117.727 147.954 152.699 1.00 17.13  ? 545 LEU C C   1 
ATOM   13506 O O   . LEU C 1 545 ? 117.343 148.029 153.861 1.00 27.95  ? 545 LEU C O   1 
ATOM   13507 C CB  . LEU C 1 545 ? 119.672 149.472 152.164 1.00 24.28  ? 545 LEU C CB  1 
ATOM   13508 C CG  . LEU C 1 545 ? 121.192 149.701 152.237 1.00 26.90  ? 545 LEU C CG  1 
ATOM   13509 C CD1 . LEU C 1 545 ? 121.465 151.182 152.003 1.00 26.33  ? 545 LEU C CD1 1 
ATOM   13510 C CD2 . LEU C 1 545 ? 121.805 149.306 153.576 1.00 18.91  ? 545 LEU C CD2 1 
ATOM   13511 N N   . VAL C 1 546 ? 116.870 147.746 151.700 1.00 26.76  ? 546 VAL C N   1 
ATOM   13512 C CA  . VAL C 1 546 ? 115.449 147.457 151.932 1.00 17.52  ? 546 VAL C CA  1 
ATOM   13513 C C   . VAL C 1 546 ? 115.267 146.115 152.644 1.00 24.60  ? 546 VAL C C   1 
ATOM   13514 O O   . VAL C 1 546 ? 114.504 146.051 153.603 1.00 32.21  ? 546 VAL C O   1 
ATOM   13515 C CB  . VAL C 1 546 ? 114.648 147.540 150.622 1.00 22.01  ? 546 VAL C CB  1 
ATOM   13516 C CG1 . VAL C 1 546 ? 113.213 147.043 150.785 1.00 19.88  ? 546 VAL C CG1 1 
ATOM   13517 C CG2 . VAL C 1 546 ? 114.572 148.991 150.147 1.00 21.98  ? 546 VAL C CG2 1 
ATOM   13518 N N   . PHE C 1 547 ? 115.994 145.066 152.246 1.00 26.33  ? 547 PHE C N   1 
ATOM   13519 C CA  . PHE C 1 547 ? 115.945 143.778 152.988 1.00 13.54  ? 547 PHE C CA  1 
ATOM   13520 C C   . PHE C 1 547 ? 116.496 143.989 154.403 1.00 18.12  ? 547 PHE C C   1 
ATOM   13521 O O   . PHE C 1 547 ? 115.822 143.606 155.350 1.00 34.33  ? 547 PHE C O   1 
ATOM   13522 C CB  . PHE C 1 547 ? 116.726 142.695 152.238 1.00 18.05  ? 547 PHE C CB  1 
ATOM   13523 C CG  . PHE C 1 547 ? 115.986 142.061 151.086 1.00 23.53  ? 547 PHE C CG  1 
ATOM   13524 C CD1 . PHE C 1 547 ? 115.829 142.736 149.887 1.00 30.28  ? 547 PHE C CD1 1 
ATOM   13525 C CD2 . PHE C 1 547 ? 115.452 140.788 151.201 1.00 34.62  ? 547 PHE C CD2 1 
ATOM   13526 C CE1 . PHE C 1 547 ? 115.148 142.153 148.828 1.00 29.57  ? 547 PHE C CE1 1 
ATOM   13527 C CE2 . PHE C 1 547 ? 114.774 140.206 150.142 1.00 30.59  ? 547 PHE C CE2 1 
ATOM   13528 C CZ  . PHE C 1 547 ? 114.623 140.889 148.958 1.00 24.93  ? 547 PHE C CZ  1 
ATOM   13529 N N   . LEU C 1 548 ? 117.657 144.620 154.570 1.00 25.17  ? 548 LEU C N   1 
ATOM   13530 C CA  . LEU C 1 548 ? 118.288 144.863 155.858 1.00 16.53  ? 548 LEU C CA  1 
ATOM   13531 C C   . LEU C 1 548 ? 117.361 145.598 156.820 1.00 15.31  ? 548 LEU C C   1 
ATOM   13532 O O   . LEU C 1 548 ? 117.082 145.099 157.904 1.00 33.86  ? 548 LEU C O   1 
ATOM   13533 C CB  . LEU C 1 548 ? 119.591 145.642 155.626 1.00 26.07  ? 548 LEU C CB  1 
ATOM   13534 C CG  . LEU C 1 548 ? 120.395 145.903 156.907 1.00 29.16  ? 548 LEU C CG  1 
ATOM   13535 C CD1 . LEU C 1 548 ? 120.981 144.603 157.436 1.00 22.31  ? 548 LEU C CD1 1 
ATOM   13536 C CD2 . LEU C 1 548 ? 121.525 146.880 156.622 1.00 26.04  ? 548 LEU C CD2 1 
ATOM   13537 N N   . PHE C 1 549 ? 116.853 146.769 156.447 1.00 20.69  ? 549 PHE C N   1 
ATOM   13538 C CA  . PHE C 1 549 ? 116.036 147.563 157.350 1.00 22.94  ? 549 PHE C CA  1 
ATOM   13539 C C   . PHE C 1 549 ? 114.626 147.002 157.540 1.00 21.46  ? 549 PHE C C   1 
ATOM   13540 O O   . PHE C 1 549 ? 114.120 147.055 158.656 1.00 37.55  ? 549 PHE C O   1 
ATOM   13541 C CB  . PHE C 1 549 ? 116.053 149.033 156.921 1.00 23.52  ? 549 PHE C CB  1 
ATOM   13542 C CG  . PHE C 1 549 ? 117.444 149.652 156.896 1.00 32.21  ? 549 PHE C CG  1 
ATOM   13543 C CD1 . PHE C 1 549 ? 118.346 149.449 157.961 1.00 28.05  ? 549 PHE C CD1 1 
ATOM   13544 C CD2 . PHE C 1 549 ? 117.841 150.448 155.808 1.00 35.09  ? 549 PHE C CD2 1 
ATOM   13545 C CE1 . PHE C 1 549 ? 119.630 150.011 157.925 1.00 26.13  ? 549 PHE C CE1 1 
ATOM   13546 C CE2 . PHE C 1 549 ? 119.126 151.016 155.776 1.00 30.84  ? 549 PHE C CE2 1 
ATOM   13547 C CZ  . PHE C 1 549 ? 120.022 150.794 156.828 1.00 27.61  ? 549 PHE C CZ  1 
ATOM   13548 N N   . GLY C 1 550 ? 114.021 146.382 156.525 1.00 17.43  ? 550 GLY C N   1 
ATOM   13549 C CA  . GLY C 1 550 ? 112.742 145.690 156.657 1.00 14.65  ? 550 GLY C CA  1 
ATOM   13550 C C   . GLY C 1 550 ? 112.786 144.543 157.667 1.00 22.20  ? 550 GLY C C   1 
ATOM   13551 O O   . GLY C 1 550 ? 111.928 144.465 158.543 1.00 32.42  ? 550 GLY C O   1 
ATOM   13552 N N   . PHE C 1 551 ? 113.808 143.683 157.613 1.00 19.87  ? 551 PHE C N   1 
ATOM   13553 C CA  . PHE C 1 551 ? 113.992 142.637 158.615 1.00 11.81  ? 551 PHE C CA  1 
ATOM   13554 C C   . PHE C 1 551 ? 114.502 143.173 159.963 1.00 15.32  ? 551 PHE C C   1 
ATOM   13555 O O   . PHE C 1 551 ? 114.125 142.631 160.995 1.00 26.23  ? 551 PHE C O   1 
ATOM   13556 C CB  . PHE C 1 551 ? 114.880 141.521 158.056 1.00 10.67  ? 551 PHE C CB  1 
ATOM   13557 C CG  . PHE C 1 551 ? 114.153 140.539 157.161 1.00 12.88  ? 551 PHE C CG  1 
ATOM   13558 C CD1 . PHE C 1 551 ? 113.511 139.425 157.728 1.00 12.08  ? 551 PHE C CD1 1 
ATOM   13559 C CD2 . PHE C 1 551 ? 114.144 140.693 155.762 1.00 11.13  ? 551 PHE C CD2 1 
ATOM   13560 C CE1 . PHE C 1 551 ? 112.886 138.474 156.912 1.00 12.39  ? 551 PHE C CE1 1 
ATOM   13561 C CE2 . PHE C 1 551 ? 113.528 139.742 154.946 1.00 7.38   ? 551 PHE C CE2 1 
ATOM   13562 C CZ  . PHE C 1 551 ? 112.900 138.624 155.518 1.00 17.30  ? 551 PHE C CZ  1 
ATOM   13563 N N   . ALA C 1 552 ? 115.286 144.252 160.013 1.00 21.79  ? 552 ALA C N   1 
ATOM   13564 C CA  . ALA C 1 552 ? 115.706 144.854 161.273 1.00 18.96  ? 552 ALA C CA  1 
ATOM   13565 C C   . ALA C 1 552 ? 114.530 145.421 162.086 1.00 24.72  ? 552 ALA C C   1 
ATOM   13566 O O   . ALA C 1 552 ? 114.420 145.113 163.269 1.00 32.93  ? 552 ALA C O   1 
ATOM   13567 C CB  . ALA C 1 552 ? 116.763 145.928 161.008 1.00 20.55  ? 552 ALA C CB  1 
ATOM   13568 N N   . VAL C 1 553 ? 113.615 146.196 161.484 1.00 27.90  ? 553 VAL C N   1 
ATOM   13569 C CA  . VAL C 1 553 ? 112.430 146.705 162.203 1.00 23.67  ? 553 VAL C CA  1 
ATOM   13570 C C   . VAL C 1 553 ? 111.540 145.567 162.693 1.00 21.27  ? 553 VAL C C   1 
ATOM   13571 O O   . VAL C 1 553 ? 111.028 145.623 163.807 1.00 25.54  ? 553 VAL C O   1 
ATOM   13572 C CB  . VAL C 1 553 ? 111.614 147.743 161.396 1.00 23.54  ? 553 VAL C CB  1 
ATOM   13573 C CG1 . VAL C 1 553 ? 112.435 148.992 161.088 1.00 23.23  ? 553 VAL C CG1 1 
ATOM   13574 C CG2 . VAL C 1 553 ? 111.007 147.244 160.084 1.00 22.05  ? 553 VAL C CG2 1 
ATOM   13575 N N   . ALA C 1 554 ? 111.410 144.502 161.908 1.00 22.00  ? 554 ALA C N   1 
ATOM   13576 C CA  . ALA C 1 554 ? 110.646 143.314 162.256 1.00 17.02  ? 554 ALA C CA  1 
ATOM   13577 C C   . ALA C 1 554 ? 111.231 142.525 163.435 1.00 22.95  ? 554 ALA C C   1 
ATOM   13578 O O   . ALA C 1 554 ? 110.504 142.225 164.381 1.00 27.73  ? 554 ALA C O   1 
ATOM   13579 C CB  . ALA C 1 554 ? 110.554 142.465 160.999 1.00 17.90  ? 554 ALA C CB  1 
ATOM   13580 N N   . LEU C 1 555 ? 112.536 142.238 163.434 1.00 30.11  ? 555 LEU C N   1 
ATOM   13581 C CA  . LEU C 1 555 ? 113.207 141.556 164.542 1.00 24.47  ? 555 LEU C CA  1 
ATOM   13582 C C   . LEU C 1 555 ? 113.165 142.356 165.838 1.00 25.43  ? 555 LEU C C   1 
ATOM   13583 O O   . LEU C 1 555 ? 112.875 141.783 166.883 1.00 30.90  ? 555 LEU C O   1 
ATOM   13584 C CB  . LEU C 1 555 ? 114.664 141.239 164.174 1.00 26.90  ? 555 LEU C CB  1 
ATOM   13585 C CG  . LEU C 1 555 ? 114.804 140.108 163.149 1.00 28.28  ? 555 LEU C CG  1 
ATOM   13586 C CD1 . LEU C 1 555 ? 116.259 140.014 162.726 1.00 32.03  ? 555 LEU C CD1 1 
ATOM   13587 C CD2 . LEU C 1 555 ? 114.403 138.749 163.711 1.00 27.83  ? 555 LEU C CD2 1 
ATOM   13588 N N   . VAL C 1 556 ? 113.391 143.669 165.795 1.00 22.70  ? 556 VAL C N   1 
ATOM   13589 C CA  . VAL C 1 556 ? 113.291 144.517 166.989 1.00 27.39  ? 556 VAL C CA  1 
ATOM   13590 C C   . VAL C 1 556 ? 111.878 144.511 167.558 1.00 29.23  ? 556 VAL C C   1 
ATOM   13591 O O   . VAL C 1 556 ? 111.705 144.305 168.753 1.00 34.43  ? 556 VAL C O   1 
ATOM   13592 C CB  . VAL C 1 556 ? 113.766 145.948 166.697 1.00 27.41  ? 556 VAL C CB  1 
ATOM   13593 C CG1 . VAL C 1 556 ? 113.542 146.905 167.866 1.00 27.23  ? 556 VAL C CG1 1 
ATOM   13594 C CG2 . VAL C 1 556 ? 115.260 145.934 166.410 1.00 29.29  ? 556 VAL C CG2 1 
ATOM   13595 N N   . SER C 1 557 ? 110.860 144.662 166.710 1.00 35.18  ? 557 SER C N   1 
ATOM   13596 C CA  . SER C 1 557 ? 109.453 144.660 167.127 1.00 27.01  ? 557 SER C CA  1 
ATOM   13597 C C   . SER C 1 557 ? 109.027 143.341 167.774 1.00 30.70  ? 557 SER C C   1 
ATOM   13598 O O   . SER C 1 557 ? 108.342 143.340 168.791 1.00 36.43  ? 557 SER C O   1 
ATOM   13599 C CB  . SER C 1 557 ? 108.544 144.945 165.930 1.00 25.48  ? 557 SER C CB  1 
ATOM   13600 O OG  . SER C 1 557 ? 108.897 146.167 165.317 1.00 35.32  ? 557 SER C OG  1 
ATOM   13601 N N   . LEU C 1 558 ? 109.447 142.208 167.207 1.00 30.28  ? 558 LEU C N   1 
ATOM   13602 C CA  . LEU C 1 558 ? 109.038 140.887 167.663 1.00 28.12  ? 558 LEU C CA  1 
ATOM   13603 C C   . LEU C 1 558 ? 109.820 140.386 168.892 1.00 36.05  ? 558 LEU C C   1 
ATOM   13604 O O   . LEU C 1 558 ? 109.300 139.610 169.684 1.00 40.88  ? 558 LEU C O   1 
ATOM   13605 C CB  . LEU C 1 558 ? 109.141 139.937 166.462 1.00 22.27  ? 558 LEU C CB  1 
ATOM   13606 C CG  . LEU C 1 558 ? 108.374 138.622 166.627 1.00 29.64  ? 558 LEU C CG  1 
ATOM   13607 C CD1 . LEU C 1 558 ? 106.866 138.821 166.784 1.00 31.65  ? 558 LEU C CD1 1 
ATOM   13608 C CD2 . LEU C 1 558 ? 108.583 137.774 165.385 1.00 30.92  ? 558 LEU C CD2 1 
ATOM   13609 N N   . SER C 1 559 ? 111.044 140.871 169.103 1.00 41.73  ? 559 SER C N   1 
ATOM   13610 C CA  . SER C 1 559 ? 111.902 140.504 170.242 1.00 35.44  ? 559 SER C CA  1 
ATOM   13611 C C   . SER C 1 559 ? 111.605 141.271 171.540 1.00 42.84  ? 559 SER C C   1 
ATOM   13612 O O   . SER C 1 559 ? 112.273 141.046 172.548 1.00 50.01  ? 559 SER C O   1 
ATOM   13613 C CB  . SER C 1 559 ? 113.375 140.681 169.875 1.00 38.85  ? 559 SER C CB  1 
ATOM   13614 O OG  . SER C 1 559 ? 113.651 140.004 168.671 1.00 42.50  ? 559 SER C OG  1 
ATOM   13615 N N   . ARG C 1 560 ? 110.618 142.172 171.557 1.00 46.05  ? 560 ARG C N   1 
ATOM   13616 C CA  . ARG C 1 560 ? 110.210 142.932 172.756 1.00 46.31  ? 560 ARG C CA  1 
ATOM   13617 C C   . ARG C 1 560 ? 109.655 142.060 173.883 1.00 50.34  ? 560 ARG C C   1 
ATOM   13618 O O   . ARG C 1 560 ? 109.706 142.454 175.044 1.00 53.44  ? 560 ARG C O   1 
ATOM   13619 C CB  . ARG C 1 560 ? 109.123 143.945 172.375 1.00 46.41  ? 560 ARG C CB  1 
ATOM   13620 C CG  . ARG C 1 560 ? 109.614 145.087 171.491 1.00 44.38  ? 560 ARG C CG  1 
ATOM   13621 C CD  . ARG C 1 560 ? 110.443 146.107 172.272 1.00 47.20  ? 560 ARG C CD  1 
ATOM   13622 N NE  . ARG C 1 560 ? 111.056 147.122 171.396 1.00 52.18  ? 560 ARG C NE  1 
ATOM   13623 C CZ  . ARG C 1 560 ? 110.442 148.031 170.670 1.00 48.53  ? 560 ARG C CZ  1 
ATOM   13624 N NH1 . ARG C 1 560 ? 111.124 148.905 169.995 1.00 46.96  ? 560 ARG C NH1 1 
ATOM   13625 N NH2 . ARG C 1 560 ? 109.148 148.109 170.613 1.00 47.72  ? 560 ARG C NH2 1 
ATOM   13626 N N   . GLU C 1 561 ? 109.101 140.901 173.543 1.00 52.51  ? 561 GLU C N   1 
ATOM   13627 C CA  . GLU C 1 561 ? 108.410 140.015 174.473 1.00 54.27  ? 561 GLU C CA  1 
ATOM   13628 C C   . GLU C 1 561 ? 109.287 138.838 174.913 1.00 58.06  ? 561 GLU C C   1 
ATOM   13629 O O   . GLU C 1 561 ? 109.761 138.055 174.092 1.00 56.00  ? 561 GLU C O   1 
ATOM   13630 C CB  . GLU C 1 561 ? 107.126 139.495 173.803 1.00 55.99  ? 561 GLU C CB  1 
ATOM   13631 C CG  . GLU C 1 561 ? 106.026 140.556 173.642 1.00 57.52  ? 561 GLU C CG  1 
ATOM   13632 C CD  . GLU C 1 561 ? 105.540 141.140 174.978 1.00 60.26  ? 561 GLU C CD  1 
ATOM   13633 O OE1 . GLU C 1 561 ? 105.642 140.453 176.019 1.00 60.36  ? 561 GLU C OE1 1 
ATOM   13634 O OE2 . GLU C 1 561 ? 105.042 142.287 174.979 1.00 60.18  ? 561 GLU C OE2 1 
ATOM   13635 N N   . ALA C 1 562 ? 109.480 138.679 176.225 1.00 61.93  ? 562 ALA C N   1 
ATOM   13636 C CA  . ALA C 1 562 ? 110.183 137.549 176.820 1.00 60.80  ? 562 ALA C CA  1 
ATOM   13637 C C   . ALA C 1 562 ? 109.253 136.352 177.120 1.00 59.90  ? 562 ALA C C   1 
ATOM   13638 O O   . ALA C 1 562 ? 108.047 136.521 177.298 1.00 62.46  ? 562 ALA C O   1 
ATOM   13639 C CB  . ALA C 1 562 ? 110.899 138.044 178.076 1.00 59.37  ? 562 ALA C CB  1 
ATOM   13640 N N   . ARG C 1 563 ? 109.812 135.147 177.220 1.00 59.73  ? 563 ARG C N   1 
ATOM   13641 C CA  . ARG C 1 563 ? 109.099 133.924 177.606 1.00 62.22  ? 563 ARG C CA  1 
ATOM   13642 C C   . ARG C 1 563 ? 110.004 132.901 178.304 1.00 64.54  ? 563 ARG C C   1 
ATOM   13643 O O   . ARG C 1 563 ? 111.207 132.820 178.042 1.00 64.27  ? 563 ARG C O   1 
ATOM   13644 C CB  . ARG C 1 563 ? 108.464 133.282 176.376 1.00 59.90  ? 563 ARG C CB  1 
ATOM   13645 N N   . PRO C 1 589 ? 120.010 141.112 171.890 1.00 54.87  ? 589 PRO C N   1 
ATOM   13646 C CA  . PRO C 1 589 ? 118.603 140.758 172.018 1.00 54.32  ? 589 PRO C CA  1 
ATOM   13647 C C   . PRO C 1 589 ? 117.687 141.438 170.991 1.00 51.55  ? 589 PRO C C   1 
ATOM   13648 O O   . PRO C 1 589 ? 116.474 141.473 171.184 1.00 53.95  ? 589 PRO C O   1 
ATOM   13649 C CB  . PRO C 1 589 ? 118.231 141.125 173.459 1.00 50.66  ? 589 PRO C CB  1 
ATOM   13650 C CG  . PRO C 1 589 ? 119.553 141.030 174.209 1.00 48.34  ? 589 PRO C CG  1 
ATOM   13651 C CD  . PRO C 1 589 ? 120.553 141.519 173.167 1.00 52.58  ? 589 PRO C CD  1 
ATOM   13652 N N   . TYR C 1 590 ? 118.259 142.032 169.938 1.00 40.57  ? 590 TYR C N   1 
ATOM   13653 C CA  . TYR C 1 590 ? 117.595 142.939 168.989 1.00 37.04  ? 590 TYR C CA  1 
ATOM   13654 C C   . TYR C 1 590 ? 116.955 144.141 169.704 1.00 39.51  ? 590 TYR C C   1 
ATOM   13655 O O   . TYR C 1 590 ? 115.756 144.387 169.608 1.00 43.89  ? 590 TYR C O   1 
ATOM   13656 C CB  . TYR C 1 590 ? 116.638 142.182 168.054 1.00 36.79  ? 590 TYR C CB  1 
ATOM   13657 C CG  . TYR C 1 590 ? 117.268 140.983 167.382 1.00 36.66  ? 590 TYR C CG  1 
ATOM   13658 C CD1 . TYR C 1 590 ? 118.294 141.185 166.445 1.00 38.44  ? 590 TYR C CD1 1 
ATOM   13659 C CD2 . TYR C 1 590 ? 116.885 139.675 167.727 1.00 38.44  ? 590 TYR C CD2 1 
ATOM   13660 C CE1 . TYR C 1 590 ? 118.942 140.093 165.854 1.00 35.87  ? 590 TYR C CE1 1 
ATOM   13661 C CE2 . TYR C 1 590 ? 117.539 138.575 167.148 1.00 40.32  ? 590 TYR C CE2 1 
ATOM   13662 C CZ  . TYR C 1 590 ? 118.574 138.784 166.216 1.00 39.25  ? 590 TYR C CZ  1 
ATOM   13663 O OH  . TYR C 1 590 ? 119.249 137.735 165.690 1.00 47.47  ? 590 TYR C OH  1 
ATOM   13664 N N   . ARG C 1 591 ? 117.750 144.879 170.476 1.00 39.79  ? 591 ARG C N   1 
ATOM   13665 C CA  . ARG C 1 591 ? 117.259 145.949 171.347 1.00 40.13  ? 591 ARG C CA  1 
ATOM   13666 C C   . ARG C 1 591 ? 116.990 147.283 170.631 1.00 39.55  ? 591 ARG C C   1 
ATOM   13667 O O   . ARG C 1 591 ? 116.218 148.106 171.119 1.00 44.83  ? 591 ARG C O   1 
ATOM   13668 C CB  . ARG C 1 591 ? 118.287 146.151 172.453 1.00 39.14  ? 591 ARG C CB  1 
ATOM   13669 N N   . SER C 1 592 ? 117.610 147.517 169.477 1.00 32.75  ? 592 SER C N   1 
ATOM   13670 C CA  . SER C 1 592 ? 117.522 148.752 168.695 1.00 32.74  ? 592 SER C CA  1 
ATOM   13671 C C   . SER C 1 592 ? 117.698 148.466 167.207 1.00 33.88  ? 592 SER C C   1 
ATOM   13672 O O   . SER C 1 592 ? 118.145 147.384 166.828 1.00 39.31  ? 592 SER C O   1 
ATOM   13673 C CB  . SER C 1 592 ? 118.545 149.783 169.197 1.00 40.07  ? 592 SER C CB  1 
ATOM   13674 O OG  . SER C 1 592 ? 119.871 149.450 168.830 1.00 40.96  ? 592 SER C OG  1 
ATOM   13675 N N   . ILE C 1 593 ? 117.336 149.410 166.332 1.00 32.70  ? 593 ILE C N   1 
ATOM   13676 C CA  . ILE C 1 593 ? 117.503 149.239 164.883 1.00 27.61  ? 593 ILE C CA  1 
ATOM   13677 C C   . ILE C 1 593 ? 118.982 149.117 164.506 1.00 33.02  ? 593 ILE C C   1 
ATOM   13678 O O   . ILE C 1 593 ? 119.305 148.306 163.644 1.00 37.29  ? 593 ILE C O   1 
ATOM   13679 C CB  . ILE C 1 593 ? 116.800 150.367 164.093 1.00 33.30  ? 593 ILE C CB  1 
ATOM   13680 C CG1 . ILE C 1 593 ? 115.287 150.439 164.370 1.00 34.25  ? 593 ILE C CG1 1 
ATOM   13681 C CG2 . ILE C 1 593 ? 117.034 150.239 162.576 1.00 29.16  ? 593 ILE C CG2 1 
ATOM   13682 C CD1 . ILE C 1 593 ? 114.505 149.172 164.036 1.00 34.18  ? 593 ILE C CD1 1 
ATOM   13683 N N   . LEU C 1 594 ? 119.897 149.840 165.161 1.00 36.49  ? 594 LEU C N   1 
ATOM   13684 C CA  . LEU C 1 594 ? 121.340 149.700 164.928 1.00 31.29  ? 594 LEU C CA  1 
ATOM   13685 C C   . LEU C 1 594 ? 121.841 148.312 165.344 1.00 30.72  ? 594 LEU C C   1 
ATOM   13686 O O   . LEU C 1 594 ? 122.543 147.666 164.579 1.00 37.09  ? 594 LEU C O   1 
ATOM   13687 C CB  . LEU C 1 594 ? 122.100 150.829 165.648 1.00 38.53  ? 594 LEU C CB  1 
ATOM   13688 C CG  . LEU C 1 594 ? 123.639 150.733 165.551 1.00 41.12  ? 594 LEU C CG  1 
ATOM   13689 C CD1 . LEU C 1 594 ? 124.142 150.818 164.114 1.00 38.84  ? 594 LEU C CD1 1 
ATOM   13690 C CD2 . LEU C 1 594 ? 124.284 151.859 166.343 1.00 35.80  ? 594 LEU C CD2 1 
ATOM   13691 N N   . ASP C 1 595 ? 121.429 147.828 166.515 1.00 27.66  ? 595 ASP C N   1 
ATOM   13692 C CA  . ASP C 1 595 ? 121.764 146.495 167.009 1.00 27.82  ? 595 ASP C CA  1 
ATOM   13693 C C   . ASP C 1 595 ? 121.313 145.400 166.028 1.00 31.34  ? 595 ASP C C   1 
ATOM   13694 O O   . ASP C 1 595 ? 122.128 144.611 165.559 1.00 36.15  ? 595 ASP C O   1 
ATOM   13695 C CB  . ASP C 1 595 ? 121.113 146.326 168.391 1.00 33.90  ? 595 ASP C CB  1 
ATOM   13696 C CG  . ASP C 1 595 ? 121.395 144.988 169.070 1.00 42.60  ? 595 ASP C CG  1 
ATOM   13697 O OD1 . ASP C 1 595 ? 122.555 144.530 169.049 1.00 43.02  ? 595 ASP C OD1 1 
ATOM   13698 O OD2 . ASP C 1 595 ? 120.450 144.431 169.672 1.00 43.44  ? 595 ASP C OD2 1 
ATOM   13699 N N   . ALA C 1 596 ? 120.040 145.395 165.632 1.00 30.10  ? 596 ALA C N   1 
ATOM   13700 C CA  . ALA C 1 596 ? 119.512 144.418 164.692 1.00 19.23  ? 596 ALA C CA  1 
ATOM   13701 C C   . ALA C 1 596 ? 120.078 144.556 163.275 1.00 24.64  ? 596 ALA C C   1 
ATOM   13702 O O   . ALA C 1 596 ? 120.327 143.550 162.627 1.00 31.15  ? 596 ALA C O   1 
ATOM   13703 C CB  . ALA C 1 596 ? 117.987 144.511 164.702 1.00 24.65  ? 596 ALA C CB  1 
ATOM   13704 N N   . SER C 1 597 ? 120.341 145.773 162.792 1.00 28.40  ? 597 SER C N   1 
ATOM   13705 C CA  . SER C 1 597 ? 120.994 145.980 161.493 1.00 19.72  ? 597 SER C CA  1 
ATOM   13706 C C   . SER C 1 597 ? 122.404 145.411 161.477 1.00 21.65  ? 597 SER C C   1 
ATOM   13707 O O   . SER C 1 597 ? 122.810 144.827 160.484 1.00 30.35  ? 597 SER C O   1 
ATOM   13708 C CB  . SER C 1 597 ? 121.093 147.458 161.131 1.00 23.46  ? 597 SER C CB  1 
ATOM   13709 O OG  . SER C 1 597 ? 119.815 148.030 161.056 1.00 35.54  ? 597 SER C OG  1 
ATOM   13710 N N   . LEU C 1 598 ? 123.162 145.565 162.557 1.00 22.32  ? 598 LEU C N   1 
ATOM   13711 C CA  . LEU C 1 598 ? 124.522 145.054 162.626 1.00 21.00  ? 598 LEU C CA  1 
ATOM   13712 C C   . LEU C 1 598 ? 124.545 143.524 162.743 1.00 19.07  ? 598 LEU C C   1 
ATOM   13713 O O   . LEU C 1 598 ? 125.320 142.870 162.054 1.00 24.35  ? 598 LEU C O   1 
ATOM   13714 C CB  . LEU C 1 598 ? 125.257 145.785 163.757 1.00 26.83  ? 598 LEU C CB  1 
ATOM   13715 C CG  . LEU C 1 598 ? 126.781 145.658 163.671 1.00 30.36  ? 598 LEU C CG  1 
ATOM   13716 C CD1 . LEU C 1 598 ? 127.326 146.394 162.448 1.00 20.74  ? 598 LEU C CD1 1 
ATOM   13717 C CD2 . LEU C 1 598 ? 127.407 146.252 164.925 1.00 22.68  ? 598 LEU C CD2 1 
ATOM   13718 N N   . GLU C 1 599 ? 123.647 142.929 163.527 1.00 21.27  ? 599 GLU C N   1 
ATOM   13719 C CA  . GLU C 1 599 ? 123.453 141.477 163.562 1.00 14.57  ? 599 GLU C CA  1 
ATOM   13720 C C   . GLU C 1 599 ? 123.021 140.891 162.215 1.00 21.83  ? 599 GLU C C   1 
ATOM   13721 O O   . GLU C 1 599 ? 123.556 139.869 161.791 1.00 33.85  ? 599 GLU C O   1 
ATOM   13722 C CB  . GLU C 1 599 ? 122.419 141.106 164.636 1.00 25.85  ? 599 GLU C CB  1 
ATOM   13723 C CG  . GLU C 1 599 ? 122.898 141.302 166.080 1.00 24.81  ? 599 GLU C CG  1 
ATOM   13724 C CD  . GLU C 1 599 ? 124.228 140.605 166.389 1.00 36.56  ? 599 GLU C CD  1 
ATOM   13725 O OE1 . GLU C 1 599 ? 124.436 139.461 165.937 1.00 36.58  ? 599 GLU C OE1 1 
ATOM   13726 O OE2 . GLU C 1 599 ? 125.095 141.206 167.059 1.00 37.37  ? 599 GLU C OE2 1 
ATOM   13727 N N   . LEU C 1 600 ? 122.109 141.538 161.492 1.00 23.09  ? 600 LEU C N   1 
ATOM   13728 C CA  . LEU C 1 600 ? 121.737 141.123 160.146 1.00 7.60   ? 600 LEU C CA  1 
ATOM   13729 C C   . LEU C 1 600 ? 122.857 141.323 159.126 1.00 7.70   ? 600 LEU C C   1 
ATOM   13730 O O   . LEU C 1 600 ? 123.022 140.498 158.228 1.00 27.63  ? 600 LEU C O   1 
ATOM   13731 C CB  . LEU C 1 600 ? 120.484 141.878 159.698 1.00 20.99  ? 600 LEU C CB  1 
ATOM   13732 C CG  . LEU C 1 600 ? 119.176 141.430 160.358 1.00 7.03   ? 600 LEU C CG  1 
ATOM   13733 C CD1 . LEU C 1 600 ? 118.037 142.199 159.722 1.00 14.06  ? 600 LEU C CD1 1 
ATOM   13734 C CD2 . LEU C 1 600 ? 118.911 139.949 160.165 1.00 13.98  ? 600 LEU C CD2 1 
ATOM   13735 N N   . PHE C 1 601 ? 123.644 142.389 159.226 1.00 18.83  ? 601 PHE C N   1 
ATOM   13736 C CA  . PHE C 1 601 ? 124.778 142.615 158.341 1.00 16.41  ? 601 PHE C CA  1 
ATOM   13737 C C   . PHE C 1 601 ? 125.889 141.568 158.533 1.00 16.51  ? 601 PHE C C   1 
ATOM   13738 O O   . PHE C 1 601 ? 126.505 141.132 157.562 1.00 14.51  ? 601 PHE C O   1 
ATOM   13739 C CB  . PHE C 1 601 ? 125.294 144.047 158.519 1.00 14.10  ? 601 PHE C CB  1 
ATOM   13740 C CG  . PHE C 1 601 ? 126.433 144.365 157.577 1.00 17.13  ? 601 PHE C CG  1 
ATOM   13741 C CD1 . PHE C 1 601 ? 126.184 144.493 156.199 1.00 19.85  ? 601 PHE C CD1 1 
ATOM   13742 C CD2 . PHE C 1 601 ? 127.749 144.442 158.055 1.00 15.76  ? 601 PHE C CD2 1 
ATOM   13743 C CE1 . PHE C 1 601 ? 127.244 144.675 155.304 1.00 18.40  ? 601 PHE C CE1 1 
ATOM   13744 C CE2 . PHE C 1 601 ? 128.809 144.634 157.160 1.00 19.77  ? 601 PHE C CE2 1 
ATOM   13745 C CZ  . PHE C 1 601 ? 128.560 144.747 155.786 1.00 18.40  ? 601 PHE C CZ  1 
ATOM   13746 N N   . LYS C 1 602 ? 126.089 141.075 159.761 1.00 22.08  ? 602 LYS C N   1 
ATOM   13747 C CA  . LYS C 1 602 ? 127.076 140.038 160.077 1.00 9.24   ? 602 LYS C CA  1 
ATOM   13748 C C   . LYS C 1 602 ? 126.932 138.744 159.280 1.00 11.40  ? 602 LYS C C   1 
ATOM   13749 O O   . LYS C 1 602 ? 127.940 138.104 159.003 1.00 26.61  ? 602 LYS C O   1 
ATOM   13750 C CB  . LYS C 1 602 ? 127.128 139.785 161.590 1.00 8.83   ? 602 LYS C CB  1 
ATOM   13751 C CG  . LYS C 1 602 ? 128.078 140.810 162.214 1.00 13.86  ? 602 LYS C CG  1 
ATOM   13752 C CD  . LYS C 1 602 ? 128.387 140.568 163.688 1.00 17.19  ? 602 LYS C CD  1 
ATOM   13753 C CE  . LYS C 1 602 ? 127.220 140.934 164.591 1.00 13.84  ? 602 LYS C CE  1 
ATOM   13754 N NZ  . LYS C 1 602 ? 127.640 140.990 166.009 1.00 27.33  ? 602 LYS C NZ  1 
ATOM   13755 N N   . PHE C 1 603 ? 125.746 138.386 158.802 1.00 19.17  ? 603 PHE C N   1 
ATOM   13756 C CA  . PHE C 1 603 ? 125.570 137.260 157.884 1.00 19.97  ? 603 PHE C CA  1 
ATOM   13757 C C   . PHE C 1 603 ? 126.311 137.420 156.552 1.00 22.43  ? 603 PHE C C   1 
ATOM   13758 O O   . PHE C 1 603 ? 126.760 136.432 155.984 1.00 30.66  ? 603 PHE C O   1 
ATOM   13759 C CB  . PHE C 1 603 ? 124.082 137.033 157.628 1.00 9.82   ? 603 PHE C CB  1 
ATOM   13760 C CG  . PHE C 1 603 ? 123.354 136.465 158.818 1.00 14.63  ? 603 PHE C CG  1 
ATOM   13761 C CD1 . PHE C 1 603 ? 123.363 135.079 159.040 1.00 15.60  ? 603 PHE C CD1 1 
ATOM   13762 C CD2 . PHE C 1 603 ? 122.684 137.304 159.719 1.00 10.91  ? 603 PHE C CD2 1 
ATOM   13763 C CE1 . PHE C 1 603 ? 122.707 134.553 160.156 1.00 14.42  ? 603 PHE C CE1 1 
ATOM   13764 C CE2 . PHE C 1 603 ? 122.026 136.773 160.835 1.00 12.25  ? 603 PHE C CE2 1 
ATOM   13765 C CZ  . PHE C 1 603 ? 122.037 135.392 161.057 1.00 16.30  ? 603 PHE C CZ  1 
ATOM   13766 N N   . THR C 1 604 ? 126.494 138.641 156.055 1.00 26.75  ? 604 THR C N   1 
ATOM   13767 C CA  . THR C 1 604 ? 127.197 138.890 154.787 1.00 15.06  ? 604 THR C CA  1 
ATOM   13768 C C   . THR C 1 604 ? 128.718 138.736 154.894 1.00 13.86  ? 604 THR C C   1 
ATOM   13769 O O   . THR C 1 604 ? 129.380 138.505 153.889 1.00 28.67  ? 604 THR C O   1 
ATOM   13770 C CB  . THR C 1 604 ? 126.856 140.271 154.213 1.00 26.86  ? 604 THR C CB  1 
ATOM   13771 O OG1 . THR C 1 604 ? 127.417 141.300 154.987 1.00 32.71  ? 604 THR C OG1 1 
ATOM   13772 C CG2 . THR C 1 604 ? 125.353 140.512 154.116 1.00 23.28  ? 604 THR C CG2 1 
ATOM   13773 N N   . ILE C 1 605 ? 129.273 138.819 156.104 1.00 17.95  ? 605 ILE C N   1 
ATOM   13774 C CA  . ILE C 1 605 ? 130.706 138.691 156.392 1.00 15.20  ? 605 ILE C CA  1 
ATOM   13775 C C   . ILE C 1 605 ? 131.071 137.346 157.047 1.00 15.06  ? 605 ILE C C   1 
ATOM   13776 O O   . ILE C 1 605 ? 132.170 137.178 157.560 1.00 26.29  ? 605 ILE C O   1 
ATOM   13777 C CB  . ILE C 1 605 ? 131.232 139.913 157.172 1.00 11.53  ? 605 ILE C CB  1 
ATOM   13778 C CG1 . ILE C 1 605 ? 130.582 140.055 158.555 1.00 14.17  ? 605 ILE C CG1 1 
ATOM   13779 C CG2 . ILE C 1 605 ? 131.056 141.203 156.370 1.00 12.61  ? 605 ILE C CG2 1 
ATOM   13780 C CD1 . ILE C 1 605 ? 131.430 140.843 159.542 1.00 10.18  ? 605 ILE C CD1 1 
ATOM   13781 N N   . GLY C 1 606 ? 130.156 136.377 157.045 1.00 10.51  ? 606 GLY C N   1 
ATOM   13782 C CA  . GLY C 1 606 ? 130.376 135.047 157.607 1.00 0.00   ? 606 GLY C CA  1 
ATOM   13783 C C   . GLY C 1 606 ? 130.320 134.965 159.132 1.00 3.54   ? 606 GLY C C   1 
ATOM   13784 O O   . GLY C 1 606 ? 130.895 134.050 159.692 1.00 26.13  ? 606 GLY C O   1 
ATOM   13785 N N   . MET C 1 607 ? 129.649 135.900 159.807 1.00 15.85  ? 607 MET C N   1 
ATOM   13786 C CA  . MET C 1 607 ? 129.653 136.049 161.269 1.00 0.83   ? 607 MET C CA  1 
ATOM   13787 C C   . MET C 1 607 ? 128.265 136.065 161.926 1.00 13.35  ? 607 MET C C   1 
ATOM   13788 O O   . MET C 1 607 ? 128.140 136.407 163.097 1.00 15.20  ? 607 MET C O   1 
ATOM   13789 C CB  . MET C 1 607 ? 130.467 137.298 161.638 1.00 16.92  ? 607 MET C CB  1 
ATOM   13790 C CG  . MET C 1 607 ? 131.966 137.062 161.480 1.00 0.00   ? 607 MET C CG  1 
ATOM   13791 S SD  . MET C 1 607 ? 132.700 135.978 162.736 1.00 23.99  ? 607 MET C SD  1 
ATOM   13792 C CE  . MET C 1 607 ? 132.633 137.013 164.205 1.00 9.31   ? 607 MET C CE  1 
ATOM   13793 N N   . GLY C 1 608 ? 127.202 135.734 161.190 1.00 13.82  ? 608 GLY C N   1 
ATOM   13794 C CA  . GLY C 1 608 ? 125.824 135.841 161.665 1.00 5.67   ? 608 GLY C CA  1 
ATOM   13795 C C   . GLY C 1 608 ? 125.406 134.749 162.648 1.00 17.97  ? 608 GLY C C   1 
ATOM   13796 O O   . GLY C 1 608 ? 125.524 133.566 162.367 1.00 30.12  ? 608 GLY C O   1 
ATOM   13797 N N   . GLU C 1 609 ? 124.870 135.121 163.803 1.00 32.67  ? 609 GLU C N   1 
ATOM   13798 C CA  . GLU C 1 609 ? 124.389 134.160 164.797 1.00 28.62  ? 609 GLU C CA  1 
ATOM   13799 C C   . GLU C 1 609 ? 122.960 133.678 164.500 1.00 33.45  ? 609 GLU C C   1 
ATOM   13800 O O   . GLU C 1 609 ? 122.009 134.456 164.562 1.00 39.59  ? 609 GLU C O   1 
ATOM   13801 C CB  . GLU C 1 609 ? 124.489 134.764 166.204 1.00 31.73  ? 609 GLU C CB  1 
ATOM   13802 C CG  . GLU C 1 609 ? 125.933 134.953 166.699 1.00 36.83  ? 609 GLU C CG  1 
ATOM   13803 C CD  . GLU C 1 609 ? 126.660 133.650 167.082 1.00 47.46  ? 609 GLU C CD  1 
ATOM   13804 O OE1 . GLU C 1 609 ? 126.090 132.547 166.926 1.00 47.74  ? 609 GLU C OE1 1 
ATOM   13805 O OE2 . GLU C 1 609 ? 127.802 133.730 167.576 1.00 41.00  ? 609 GLU C OE2 1 
ATOM   13806 N N   . LEU C 1 610 ? 122.791 132.375 164.252 1.00 34.60  ? 610 LEU C N   1 
ATOM   13807 C CA  . LEU C 1 610 ? 121.496 131.689 164.303 1.00 27.87  ? 610 LEU C CA  1 
ATOM   13808 C C   . LEU C 1 610 ? 121.383 130.875 165.590 1.00 34.29  ? 610 LEU C C   1 
ATOM   13809 O O   . LEU C 1 610 ? 122.211 130.009 165.876 1.00 38.89  ? 610 LEU C O   1 
ATOM   13810 C CB  . LEU C 1 610 ? 121.305 130.723 163.127 1.00 28.23  ? 610 LEU C CB  1 
ATOM   13811 C CG  . LEU C 1 610 ? 121.202 131.356 161.746 1.00 32.26  ? 610 LEU C CG  1 
ATOM   13812 C CD1 . LEU C 1 610 ? 121.229 130.261 160.690 1.00 35.78  ? 610 LEU C CD1 1 
ATOM   13813 C CD2 . LEU C 1 610 ? 119.914 132.150 161.550 1.00 32.25  ? 610 LEU C CD2 1 
ATOM   13814 N N   . ALA C 1 611 ? 120.313 131.107 166.332 1.00 43.95  ? 611 ALA C N   1 
ATOM   13815 C CA  . ALA C 1 611 ? 119.953 130.324 167.499 1.00 42.09  ? 611 ALA C CA  1 
ATOM   13816 C C   . ALA C 1 611 ? 118.435 130.249 167.611 1.00 44.77  ? 611 ALA C C   1 
ATOM   13817 O O   . ALA C 1 611 ? 117.743 131.226 167.325 1.00 47.94  ? 611 ALA C O   1 
ATOM   13818 C CB  . ALA C 1 611 ? 120.577 130.982 168.732 1.00 39.91  ? 611 ALA C CB  1 
ATOM   13819 N N   . PHE C 1 612 ? 117.902 129.122 168.083 1.00 51.49  ? 612 PHE C N   1 
ATOM   13820 C CA  . PHE C 1 612 ? 116.551 129.080 168.629 1.00 49.69  ? 612 PHE C CA  1 
ATOM   13821 C C   . PHE C 1 612 ? 116.585 129.763 170.004 1.00 50.93  ? 612 PHE C C   1 
ATOM   13822 O O   . PHE C 1 612 ? 116.975 129.173 171.010 1.00 51.66  ? 612 PHE C O   1 
ATOM   13823 C CB  . PHE C 1 612 ? 116.069 127.629 168.654 1.00 49.42  ? 612 PHE C CB  1 
ATOM   13824 C CG  . PHE C 1 612 ? 114.613 127.471 169.023 1.00 52.15  ? 612 PHE C CG  1 
ATOM   13825 C CD1 . PHE C 1 612 ? 113.613 127.815 168.097 1.00 48.62  ? 612 PHE C CD1 1 
ATOM   13826 C CD2 . PHE C 1 612 ? 114.249 126.928 170.268 1.00 52.67  ? 612 PHE C CD2 1 
ATOM   13827 C CE1 . PHE C 1 612 ? 112.261 127.600 168.405 1.00 52.96  ? 612 PHE C CE1 1 
ATOM   13828 C CE2 . PHE C 1 612 ? 112.897 126.702 170.573 1.00 51.27  ? 612 PHE C CE2 1 
ATOM   13829 C CZ  . PHE C 1 612 ? 111.904 127.033 169.639 1.00 53.44  ? 612 PHE C CZ  1 
ATOM   13830 N N   . GLN C 1 613 ? 116.308 131.064 170.010 1.00 55.85  ? 613 GLN C N   1 
ATOM   13831 C CA  . GLN C 1 613 ? 116.660 131.978 171.096 1.00 56.87  ? 613 GLN C CA  1 
ATOM   13832 C C   . GLN C 1 613 ? 115.662 131.896 172.261 1.00 58.17  ? 613 GLN C C   1 
ATOM   13833 O O   . GLN C 1 613 ? 114.661 132.607 172.294 1.00 58.22  ? 613 GLN C O   1 
ATOM   13834 C CB  . GLN C 1 613 ? 116.803 133.376 170.476 1.00 54.32  ? 613 GLN C CB  1 
ATOM   13835 C CG  . GLN C 1 613 ? 117.524 134.366 171.394 1.00 55.43  ? 613 GLN C CG  1 
ATOM   13836 C CD  . GLN C 1 613 ? 118.237 135.470 170.619 1.00 59.42  ? 613 GLN C CD  1 
ATOM   13837 O OE1 . GLN C 1 613 ? 117.942 135.774 169.475 1.00 56.55  ? 613 GLN C OE1 1 
ATOM   13838 N NE2 . GLN C 1 613 ? 119.217 136.113 171.208 1.00 60.31  ? 613 GLN C NE2 1 
ATOM   13839 N N   . GLU C 1 614 ? 115.910 130.984 173.204 1.00 63.21  ? 614 GLU C N   1 
ATOM   13840 C CA  . GLU C 1 614 ? 114.894 130.475 174.139 1.00 61.27  ? 614 GLU C CA  1 
ATOM   13841 C C   . GLU C 1 614 ? 114.196 131.532 175.012 1.00 63.59  ? 614 GLU C C   1 
ATOM   13842 O O   . GLU C 1 614 ? 113.024 131.353 175.335 1.00 62.79  ? 614 GLU C O   1 
ATOM   13843 C CB  . GLU C 1 614 ? 115.483 129.380 175.037 1.00 60.87  ? 614 GLU C CB  1 
ATOM   13844 C CG  . GLU C 1 614 ? 115.835 128.094 174.275 1.00 60.22  ? 614 GLU C CG  1 
ATOM   13845 C CD  . GLU C 1 614 ? 115.775 126.835 175.162 1.00 64.79  ? 614 GLU C CD  1 
ATOM   13846 O OE1 . GLU C 1 614 ? 115.974 126.930 176.393 1.00 65.08  ? 614 GLU C OE1 1 
ATOM   13847 O OE2 . GLU C 1 614 ? 115.524 125.737 174.628 1.00 63.71  ? 614 GLU C OE2 1 
ATOM   13848 N N   . GLN C 1 615 ? 114.872 132.653 175.296 1.00 62.95  ? 615 GLN C N   1 
ATOM   13849 C CA  . GLN C 1 615 ? 114.325 133.691 176.225 1.00 59.32  ? 615 GLN C CA  1 
ATOM   13850 C C   . GLN C 1 615 ? 113.201 134.525 175.587 1.00 62.86  ? 615 GLN C C   1 
ATOM   13851 O O   . GLN C 1 615 ? 112.507 135.229 176.348 1.00 64.23  ? 615 GLN C O   1 
ATOM   13852 C CB  . GLN C 1 615 ? 115.471 134.587 176.711 1.00 61.20  ? 615 GLN C CB  1 
ATOM   13853 C CG  . GLN C 1 615 ? 116.085 135.483 175.620 1.00 61.61  ? 615 GLN C CG  1 
ATOM   13854 C CD  . GLN C 1 615 ? 117.162 136.392 176.160 1.00 64.79  ? 615 GLN C CD  1 
ATOM   13855 O OE1 . GLN C 1 615 ? 117.457 136.396 177.354 1.00 64.43  ? 615 GLN C OE1 1 
ATOM   13856 N NE2 . GLN C 1 615 ? 117.759 137.176 175.278 1.00 64.41  ? 615 GLN C NE2 1 
ATOM   13857 N N   . LEU C 1 616 ? 113.017 134.459 174.266 1.00 59.15  ? 616 LEU C N   1 
ATOM   13858 C CA  . LEU C 1 616 ? 112.002 135.239 173.554 1.00 53.20  ? 616 LEU C CA  1 
ATOM   13859 C C   . LEU C 1 616 ? 110.661 134.501 173.490 1.00 53.29  ? 616 LEU C C   1 
ATOM   13860 O O   . LEU C 1 616 ? 110.603 133.296 173.264 1.00 55.78  ? 616 LEU C O   1 
ATOM   13861 C CB  . LEU C 1 616 ? 112.497 135.593 172.140 1.00 55.45  ? 616 LEU C CB  1 
ATOM   13862 C CG  . LEU C 1 616 ? 113.769 136.441 172.064 1.00 55.14  ? 616 LEU C CG  1 
ATOM   13863 C CD1 . LEU C 1 616 ? 114.116 136.714 170.604 1.00 49.36  ? 616 LEU C CD1 1 
ATOM   13864 C CD2 . LEU C 1 616 ? 113.621 137.777 172.781 1.00 53.97  ? 616 LEU C CD2 1 
ATOM   13865 N N   . ARG C 1 617 ? 109.612 135.343 173.393 1.00 50.29  ? 617 ARG C N   1 
ATOM   13866 C CA  . ARG C 1 617 ? 108.257 134.858 173.041 1.00 48.29  ? 617 ARG C CA  1 
ATOM   13867 C C   . ARG C 1 617 ? 108.306 134.974 171.521 1.00 55.05  ? 617 ARG C C   1 
ATOM   13868 O O   . ARG C 1 617 ? 109.010 135.883 171.038 1.00 57.28  ? 617 ARG C O   1 
ATOM   13869 C CB  . ARG C 1 617 ? 107.206 135.798 173.629 1.00 50.25  ? 617 ARG C CB  1 
ATOM   13870 C CG  . ARG C 1 617 ? 105.753 135.326 173.533 1.00 48.10  ? 617 ARG C CG  1 
ATOM   13871 C CD  . ARG C 1 617 ? 104.887 136.408 174.183 1.00 53.85  ? 617 ARG C CD  1 
ATOM   13872 N NE  . ARG C 1 617 ? 103.472 136.075 174.244 1.00 55.88  ? 617 ARG C NE  1 
ATOM   13873 C CZ  . ARG C 1 617 ? 102.555 136.820 174.852 1.00 57.83  ? 617 ARG C CZ  1 
ATOM   13874 N NH1 . ARG C 1 617 ? 101.290 136.440 174.858 1.00 55.30  ? 617 ARG C NH1 1 
ATOM   13875 N NH2 . ARG C 1 617 ? 102.910 137.939 175.457 1.00 58.19  ? 617 ARG C NH2 1 
ATOM   13876 N N   . PHE C 1 618 ? 107.614 134.116 170.790 1.00 48.42  ? 618 PHE C N   1 
ATOM   13877 C CA  . PHE C 1 618 ? 107.705 134.060 169.321 1.00 46.14  ? 618 PHE C CA  1 
ATOM   13878 C C   . PHE C 1 618 ? 109.114 133.724 168.791 1.00 45.71  ? 618 PHE C C   1 
ATOM   13879 O O   . PHE C 1 618 ? 109.435 134.025 167.643 1.00 51.18  ? 618 PHE C O   1 
ATOM   13880 C CB  . PHE C 1 618 ? 107.107 135.319 168.665 1.00 40.68  ? 618 PHE C CB  1 
ATOM   13881 C CG  . PHE C 1 618 ? 105.820 135.828 169.270 1.00 39.63  ? 618 PHE C CG  1 
ATOM   13882 C CD1 . PHE C 1 618 ? 104.640 135.079 169.134 1.00 39.29  ? 618 PHE C CD1 1 
ATOM   13883 C CD2 . PHE C 1 618 ? 105.797 137.052 169.957 1.00 40.58  ? 618 PHE C CD2 1 
ATOM   13884 C CE1 . PHE C 1 618 ? 103.439 135.562 169.667 1.00 40.53  ? 618 PHE C CE1 1 
ATOM   13885 C CE2 . PHE C 1 618 ? 104.596 137.530 170.496 1.00 41.63  ? 618 PHE C CE2 1 
ATOM   13886 C CZ  . PHE C 1 618 ? 103.417 136.790 170.345 1.00 41.41  ? 618 PHE C CZ  1 
ATOM   13887 N N   . ARG C 1 619 ? 109.913 132.999 169.597 1.00 49.16  ? 619 ARG C N   1 
ATOM   13888 C CA  . ARG C 1 619 ? 111.318 132.613 169.231 1.00 46.22  ? 619 ARG C CA  1 
ATOM   13889 C C   . ARG C 1 619 ? 111.348 131.864 167.894 1.00 45.16  ? 619 ARG C C   1 
ATOM   13890 O O   . ARG C 1 619 ? 112.278 132.117 167.103 1.00 49.02  ? 619 ARG C O   1 
ATOM   13891 C CB  . ARG C 1 619 ? 111.955 131.870 170.420 1.00 49.60  ? 619 ARG C CB  1 
ATOM   13892 C CG  . ARG C 1 619 ? 111.192 130.617 170.872 1.00 47.42  ? 619 ARG C CG  1 
ATOM   13893 C CD  . ARG C 1 619 ? 111.837 130.044 172.132 1.00 53.03  ? 619 ARG C CD  1 
ATOM   13894 N NE  . ARG C 1 619 ? 111.260 128.750 172.467 1.00 55.32  ? 619 ARG C NE  1 
ATOM   13895 C CZ  . ARG C 1 619 ? 111.575 128.034 173.539 1.00 54.39  ? 619 ARG C CZ  1 
ATOM   13896 N NH1 . ARG C 1 619 ? 110.992 126.866 173.749 1.00 53.38  ? 619 ARG C NH1 1 
ATOM   13897 N NH2 . ARG C 1 619 ? 112.467 128.488 174.400 1.00 51.50  ? 619 ARG C NH2 1 
ATOM   13898 N N   . GLY C 1 620 ? 110.374 130.991 167.650 1.00 38.48  ? 620 GLY C N   1 
ATOM   13899 C CA  . GLY C 1 620 ? 110.271 130.246 166.395 1.00 36.24  ? 620 GLY C CA  1 
ATOM   13900 C C   . GLY C 1 620 ? 110.018 131.149 165.191 1.00 35.65  ? 620 GLY C C   1 
ATOM   13901 O O   . GLY C 1 620 ? 110.625 130.959 164.144 1.00 40.80  ? 620 GLY C O   1 
ATOM   13902 N N   . VAL C 1 621 ? 109.205 132.197 165.341 1.00 37.08  ? 621 VAL C N   1 
ATOM   13903 C CA  . VAL C 1 621 ? 108.985 133.206 164.297 1.00 35.81  ? 621 VAL C CA  1 
ATOM   13904 C C   . VAL C 1 621 ? 110.222 134.094 164.114 1.00 29.44  ? 621 VAL C C   1 
ATOM   13905 O O   . VAL C 1 621 ? 110.583 134.390 162.984 1.00 33.63  ? 621 VAL C O   1 
ATOM   13906 C CB  . VAL C 1 621 ? 107.723 134.042 164.572 1.00 35.39  ? 621 VAL C CB  1 
ATOM   13907 C CG1 . VAL C 1 621 ? 107.438 135.047 163.447 1.00 35.33  ? 621 VAL C CG1 1 
ATOM   13908 C CG2 . VAL C 1 621 ? 106.479 133.156 164.708 1.00 33.60  ? 621 VAL C CG2 1 
ATOM   13909 N N   . VAL C 1 622 ? 110.936 134.442 165.187 1.00 29.69  ? 622 VAL C N   1 
ATOM   13910 C CA  . VAL C 1 622 ? 112.234 135.137 165.117 1.00 24.91  ? 622 VAL C CA  1 
ATOM   13911 C C   . VAL C 1 622 ? 113.271 134.310 164.353 1.00 30.18  ? 622 VAL C C   1 
ATOM   13912 O O   . VAL C 1 622 ? 113.942 134.836 163.472 1.00 34.00  ? 622 VAL C O   1 
ATOM   13913 C CB  . VAL C 1 622 ? 112.718 135.520 166.528 1.00 25.76  ? 622 VAL C CB  1 
ATOM   13914 C CG1 . VAL C 1 622 ? 114.163 136.021 166.571 1.00 31.88  ? 622 VAL C CG1 1 
ATOM   13915 C CG2 . VAL C 1 622 ? 111.833 136.629 167.101 1.00 27.91  ? 622 VAL C CG2 1 
ATOM   13916 N N   . LEU C 1 623 ? 113.366 133.001 164.604 1.00 31.67  ? 623 LEU C N   1 
ATOM   13917 C CA  . LEU C 1 623 ? 114.232 132.113 163.838 1.00 24.31  ? 623 LEU C CA  1 
ATOM   13918 C C   . LEU C 1 623 ? 113.804 131.997 162.366 1.00 25.46  ? 623 LEU C C   1 
ATOM   13919 O O   . LEU C 1 623 ? 114.655 132.024 161.487 1.00 36.29  ? 623 LEU C O   1 
ATOM   13920 C CB  . LEU C 1 623 ? 114.307 130.741 164.532 1.00 32.22  ? 623 LEU C CB  1 
ATOM   13921 C CG  . LEU C 1 623 ? 115.223 129.734 163.811 1.00 33.08  ? 623 LEU C CG  1 
ATOM   13922 C CD1 . LEU C 1 623 ? 116.672 130.210 163.763 1.00 30.82  ? 623 LEU C CD1 1 
ATOM   13923 C CD2 . LEU C 1 623 ? 115.193 128.385 164.515 1.00 31.54  ? 623 LEU C CD2 1 
ATOM   13924 N N   . LEU C 1 624 ? 112.508 131.907 162.068 1.00 26.84  ? 624 LEU C N   1 
ATOM   13925 C CA  . LEU C 1 624 ? 112.019 131.894 160.691 1.00 23.45  ? 624 LEU C CA  1 
ATOM   13926 C C   . LEU C 1 624 ? 112.264 133.215 159.953 1.00 27.42  ? 624 LEU C C   1 
ATOM   13927 O O   . LEU C 1 624 ? 112.599 133.176 158.775 1.00 30.91  ? 624 LEU C O   1 
ATOM   13928 C CB  . LEU C 1 624 ? 110.529 131.518 160.663 1.00 33.65  ? 624 LEU C CB  1 
ATOM   13929 C CG  . LEU C 1 624 ? 110.247 130.048 161.006 1.00 36.55  ? 624 LEU C CG  1 
ATOM   13930 C CD1 . LEU C 1 624 ? 108.743 129.861 161.185 1.00 32.51  ? 624 LEU C CD1 1 
ATOM   13931 C CD2 . LEU C 1 624 ? 110.723 129.090 159.914 1.00 27.71  ? 624 LEU C CD2 1 
ATOM   13932 N N   . LEU C 1 625 ? 112.162 134.374 160.613 1.00 30.25  ? 625 LEU C N   1 
ATOM   13933 C CA  . LEU C 1 625 ? 112.580 135.661 160.052 1.00 19.89  ? 625 LEU C CA  1 
ATOM   13934 C C   . LEU C 1 625 ? 114.073 135.680 159.721 1.00 19.98  ? 625 LEU C C   1 
ATOM   13935 O O   . LEU C 1 625 ? 114.443 136.116 158.637 1.00 32.40  ? 625 LEU C O   1 
ATOM   13936 C CB  . LEU C 1 625 ? 112.262 136.814 161.023 1.00 30.12  ? 625 LEU C CB  1 
ATOM   13937 C CG  . LEU C 1 625 ? 110.789 137.228 161.101 1.00 28.72  ? 625 LEU C CG  1 
ATOM   13938 C CD1 . LEU C 1 625 ? 110.612 138.257 162.219 1.00 28.41  ? 625 LEU C CD1 1 
ATOM   13939 C CD2 . LEU C 1 625 ? 110.303 137.863 159.801 1.00 26.71  ? 625 LEU C CD2 1 
ATOM   13940 N N   . LEU C 1 626 ? 114.938 135.192 160.615 1.00 20.32  ? 626 LEU C N   1 
ATOM   13941 C CA  . LEU C 1 626 ? 116.371 135.088 160.350 1.00 19.10  ? 626 LEU C CA  1 
ATOM   13942 C C   . LEU C 1 626 ? 116.675 134.131 159.199 1.00 18.91  ? 626 LEU C C   1 
ATOM   13943 O O   . LEU C 1 626 ? 117.416 134.493 158.297 1.00 30.86  ? 626 LEU C O   1 
ATOM   13944 C CB  . LEU C 1 626 ? 117.118 134.650 161.615 1.00 28.01  ? 626 LEU C CB  1 
ATOM   13945 C CG  . LEU C 1 626 ? 117.198 135.729 162.696 1.00 22.99  ? 626 LEU C CG  1 
ATOM   13946 C CD1 . LEU C 1 626 ? 117.694 135.103 163.994 1.00 25.86  ? 626 LEU C CD1 1 
ATOM   13947 C CD2 . LEU C 1 626 ? 118.154 136.842 162.287 1.00 18.17  ? 626 LEU C CD2 1 
ATOM   13948 N N   . LEU C 1 627 ? 116.080 132.939 159.173 1.00 21.80  ? 627 LEU C N   1 
ATOM   13949 C CA  . LEU C 1 627 ? 116.253 132.001 158.070 1.00 17.73  ? 627 LEU C CA  1 
ATOM   13950 C C   . LEU C 1 627 ? 115.741 132.578 156.744 1.00 12.70  ? 627 LEU C C   1 
ATOM   13951 O O   . LEU C 1 627 ? 116.422 132.456 155.737 1.00 30.79  ? 627 LEU C O   1 
ATOM   13952 C CB  . LEU C 1 627 ? 115.587 130.655 158.401 1.00 22.68  ? 627 LEU C CB  1 
ATOM   13953 C CG  . LEU C 1 627 ? 116.284 129.857 159.519 1.00 25.55  ? 627 LEU C CG  1 
ATOM   13954 C CD1 . LEU C 1 627 ? 115.426 128.654 159.889 1.00 22.00  ? 627 LEU C CD1 1 
ATOM   13955 C CD2 . LEU C 1 627 ? 117.665 129.362 159.114 1.00 20.39  ? 627 LEU C CD2 1 
ATOM   13956 N N   . ALA C 1 628 ? 114.592 133.258 156.726 1.00 23.87  ? 628 ALA C N   1 
ATOM   13957 C CA  . ALA C 1 628 ? 114.107 133.968 155.548 1.00 9.93   ? 628 ALA C CA  1 
ATOM   13958 C C   . ALA C 1 628 ? 115.058 135.084 155.095 1.00 16.87  ? 628 ALA C C   1 
ATOM   13959 O O   . ALA C 1 628 ? 115.388 135.142 153.918 1.00 26.01  ? 628 ALA C O   1 
ATOM   13960 C CB  . ALA C 1 628 ? 112.707 134.507 155.822 1.00 19.84  ? 628 ALA C CB  1 
ATOM   13961 N N   . TYR C 1 629 ? 115.558 135.935 155.996 1.00 16.75  ? 629 TYR C N   1 
ATOM   13962 C CA  . TYR C 1 629 ? 116.546 136.948 155.653 1.00 6.28   ? 629 TYR C CA  1 
ATOM   13963 C C   . TYR C 1 629 ? 117.822 136.337 155.062 1.00 15.99  ? 629 TYR C C   1 
ATOM   13964 O O   . TYR C 1 629 ? 118.314 136.824 154.048 1.00 23.77  ? 629 TYR C O   1 
ATOM   13965 C CB  . TYR C 1 629 ? 116.875 137.807 156.880 1.00 5.28   ? 629 TYR C CB  1 
ATOM   13966 C CG  . TYR C 1 629 ? 118.079 138.701 156.682 1.00 15.81  ? 629 TYR C CG  1 
ATOM   13967 C CD1 . TYR C 1 629 ? 117.953 139.962 156.067 1.00 9.76   ? 629 TYR C CD1 1 
ATOM   13968 C CD2 . TYR C 1 629 ? 119.351 138.218 157.042 1.00 17.01  ? 629 TYR C CD2 1 
ATOM   13969 C CE1 . TYR C 1 629 ? 119.096 140.745 155.833 1.00 5.27   ? 629 TYR C CE1 1 
ATOM   13970 C CE2 . TYR C 1 629 ? 120.487 138.994 156.803 1.00 7.54   ? 629 TYR C CE2 1 
ATOM   13971 C CZ  . TYR C 1 629 ? 120.368 140.257 156.194 1.00 15.97  ? 629 TYR C CZ  1 
ATOM   13972 O OH  . TYR C 1 629 ? 121.482 141.006 156.022 1.00 29.31  ? 629 TYR C OH  1 
ATOM   13973 N N   . VAL C 1 630 ? 118.359 135.264 155.648 1.00 17.51  ? 630 VAL C N   1 
ATOM   13974 C CA  . VAL C 1 630 ? 119.557 134.580 155.146 1.00 18.70  ? 630 VAL C CA  1 
ATOM   13975 C C   . VAL C 1 630 ? 119.333 134.041 153.740 1.00 18.25  ? 630 VAL C C   1 
ATOM   13976 O O   . VAL C 1 630 ? 120.113 134.338 152.839 1.00 28.99  ? 630 VAL C O   1 
ATOM   13977 C CB  . VAL C 1 630 ? 119.985 133.460 156.109 1.00 26.54  ? 630 VAL C CB  1 
ATOM   13978 C CG1 . VAL C 1 630 ? 121.031 132.519 155.510 1.00 26.33  ? 630 VAL C CG1 1 
ATOM   13979 C CG2 . VAL C 1 630 ? 120.589 134.061 157.375 1.00 11.69  ? 630 VAL C CG2 1 
ATOM   13980 N N   . LEU C 1 631 ? 118.251 133.298 153.516 1.00 19.24  ? 631 LEU C N   1 
ATOM   13981 C CA  . LEU C 1 631 ? 117.939 132.728 152.211 1.00 12.55  ? 631 LEU C CA  1 
ATOM   13982 C C   . LEU C 1 631 ? 117.672 133.810 151.152 1.00 23.87  ? 631 LEU C C   1 
ATOM   13983 O O   . LEU C 1 631 ? 118.211 133.725 150.057 1.00 33.83  ? 631 LEU C O   1 
ATOM   13984 C CB  . LEU C 1 631 ? 116.768 131.747 152.353 1.00 23.19  ? 631 LEU C CB  1 
ATOM   13985 C CG  . LEU C 1 631 ? 117.083 130.507 153.215 1.00 27.07  ? 631 LEU C CG  1 
ATOM   13986 C CD1 . LEU C 1 631 ? 115.801 129.727 153.478 1.00 25.75  ? 631 LEU C CD1 1 
ATOM   13987 C CD2 . LEU C 1 631 ? 118.093 129.574 152.553 1.00 22.48  ? 631 LEU C CD2 1 
ATOM   13988 N N   . LEU C 1 632 ? 116.926 134.871 151.467 1.00 18.97  ? 632 LEU C N   1 
ATOM   13989 C CA  . LEU C 1 632 ? 116.728 136.009 150.562 1.00 11.83  ? 632 LEU C CA  1 
ATOM   13990 C C   . LEU C 1 632 ? 118.028 136.745 150.244 1.00 8.93   ? 632 LEU C C   1 
ATOM   13991 O O   . LEU C 1 632 ? 118.290 137.082 149.098 1.00 29.87  ? 632 LEU C O   1 
ATOM   13992 C CB  . LEU C 1 632 ? 115.728 136.994 151.183 1.00 23.81  ? 632 LEU C CB  1 
ATOM   13993 C CG  . LEU C 1 632 ? 114.285 136.481 151.240 1.00 22.99  ? 632 LEU C CG  1 
ATOM   13994 C CD1 . LEU C 1 632 ? 113.428 137.421 152.068 1.00 20.41  ? 632 LEU C CD1 1 
ATOM   13995 C CD2 . LEU C 1 632 ? 113.670 136.397 149.856 1.00 18.01  ? 632 LEU C CD2 1 
ATOM   13996 N N   . THR C 1 633 ? 118.874 136.973 151.244 1.00 27.45  ? 633 THR C N   1 
ATOM   13997 C CA  . THR C 1 633 ? 120.159 137.660 151.080 1.00 18.98  ? 633 THR C CA  1 
ATOM   13998 C C   . THR C 1 633 ? 121.134 136.834 150.251 1.00 14.74  ? 633 THR C C   1 
ATOM   13999 O O   . THR C 1 633 ? 121.839 137.384 149.416 1.00 28.45  ? 633 THR C O   1 
ATOM   14000 C CB  . THR C 1 633 ? 120.746 137.992 152.454 1.00 17.84  ? 633 THR C CB  1 
ATOM   14001 O OG1 . THR C 1 633 ? 119.851 138.842 153.106 1.00 23.68  ? 633 THR C OG1 1 
ATOM   14002 C CG2 . THR C 1 633 ? 122.088 138.707 152.418 1.00 24.95  ? 633 THR C CG2 1 
ATOM   14003 N N   . TYR C 1 634 ? 121.154 135.515 150.412 1.00 20.58  ? 634 TYR C N   1 
ATOM   14004 C CA  . TYR C 1 634 ? 122.010 134.631 149.627 1.00 15.36  ? 634 TYR C CA  1 
ATOM   14005 C C   . TYR C 1 634 ? 121.514 134.499 148.180 1.00 20.26  ? 634 TYR C C   1 
ATOM   14006 O O   . TYR C 1 634 ? 122.339 134.496 147.270 1.00 29.47  ? 634 TYR C O   1 
ATOM   14007 C CB  . TYR C 1 634 ? 122.191 133.270 150.303 1.00 22.68  ? 634 TYR C CB  1 
ATOM   14008 C CG  . TYR C 1 634 ? 123.205 133.307 151.419 1.00 33.91  ? 634 TYR C CG  1 
ATOM   14009 C CD1 . TYR C 1 634 ? 123.390 134.463 152.163 1.00 36.83  ? 634 TYR C CD1 1 
ATOM   14010 C CD2 . TYR C 1 634 ? 123.989 132.210 151.731 1.00 30.24  ? 634 TYR C CD2 1 
ATOM   14011 C CE1 . TYR C 1 634 ? 124.316 134.532 153.187 1.00 25.80  ? 634 TYR C CE1 1 
ATOM   14012 C CE2 . TYR C 1 634 ? 124.925 132.260 152.752 1.00 26.82  ? 634 TYR C CE2 1 
ATOM   14013 C CZ  . TYR C 1 634 ? 125.088 133.426 153.481 1.00 30.48  ? 634 TYR C CZ  1 
ATOM   14014 O OH  . TYR C 1 634 ? 126.000 133.499 154.491 1.00 37.21  ? 634 TYR C OH  1 
ATOM   14015 N N   . VAL C 1 635 ? 120.197 134.484 147.951 1.00 24.04  ? 635 VAL C N   1 
ATOM   14016 C CA  . VAL C 1 635 ? 119.596 134.619 146.621 1.00 18.90  ? 635 VAL C CA  1 
ATOM   14017 C C   . VAL C 1 635 ? 119.979 135.959 145.990 1.00 17.54  ? 635 VAL C C   1 
ATOM   14018 O O   . VAL C 1 635 ? 120.415 135.977 144.847 1.00 27.82  ? 635 VAL C O   1 
ATOM   14019 C CB  . VAL C 1 635 ? 118.066 134.455 146.682 1.00 24.50  ? 635 VAL C CB  1 
ATOM   14020 C CG1 . VAL C 1 635 ? 117.365 134.782 145.359 1.00 24.17  ? 635 VAL C CG1 1 
ATOM   14021 C CG2 . VAL C 1 635 ? 117.653 133.030 147.025 1.00 24.95  ? 635 VAL C CG2 1 
ATOM   14022 N N   . LEU C 1 636 ? 119.872 137.081 146.706 1.00 15.80  ? 636 LEU C N   1 
ATOM   14023 C CA  . LEU C 1 636 ? 120.267 138.400 146.212 1.00 12.37  ? 636 LEU C CA  1 
ATOM   14024 C C   . LEU C 1 636 ? 121.767 138.504 145.903 1.00 18.40  ? 636 LEU C C   1 
ATOM   14025 O O   . LEU C 1 636 ? 122.123 138.995 144.841 1.00 31.14  ? 636 LEU C O   1 
ATOM   14026 C CB  . LEU C 1 636 ? 119.819 139.457 147.236 1.00 23.96  ? 636 LEU C CB  1 
ATOM   14027 C CG  . LEU C 1 636 ? 120.287 140.893 146.930 1.00 28.74  ? 636 LEU C CG  1 
ATOM   14028 C CD1 . LEU C 1 636 ? 119.600 141.470 145.702 1.00 26.57  ? 636 LEU C CD1 1 
ATOM   14029 C CD2 . LEU C 1 636 ? 119.996 141.800 148.117 1.00 30.03  ? 636 LEU C CD2 1 
ATOM   14030 N N   . LEU C 1 637 ? 122.649 138.040 146.790 1.00 18.86  ? 637 LEU C N   1 
ATOM   14031 C CA  . LEU C 1 637 ? 124.096 138.072 146.580 1.00 14.46  ? 637 LEU C CA  1 
ATOM   14032 C C   . LEU C 1 637 ? 124.513 137.183 145.409 1.00 20.10  ? 637 LEU C C   1 
ATOM   14033 O O   . LEU C 1 637 ? 125.301 137.597 144.572 1.00 23.17  ? 637 LEU C O   1 
ATOM   14034 C CB  . LEU C 1 637 ? 124.823 137.656 147.869 1.00 24.62  ? 637 LEU C CB  1 
ATOM   14035 C CG  . LEU C 1 637 ? 124.781 138.717 148.987 1.00 28.24  ? 637 LEU C CG  1 
ATOM   14036 C CD1 . LEU C 1 637 ? 125.263 138.105 150.302 1.00 25.87  ? 637 LEU C CD1 1 
ATOM   14037 C CD2 . LEU C 1 637 ? 125.669 139.914 148.671 1.00 23.64  ? 637 LEU C CD2 1 
ATOM   14038 N N   . LEU C 1 638 ? 123.945 135.990 145.295 1.00 22.53  ? 638 LEU C N   1 
ATOM   14039 C CA  . LEU C 1 638 ? 124.201 135.081 144.189 1.00 18.92  ? 638 LEU C CA  1 
ATOM   14040 C C   . LEU C 1 638 ? 123.715 135.641 142.848 1.00 15.03  ? 638 LEU C C   1 
ATOM   14041 O O   . LEU C 1 638 ? 124.445 135.614 141.869 1.00 29.96  ? 638 LEU C O   1 
ATOM   14042 C CB  . LEU C 1 638 ? 123.551 133.744 144.560 1.00 25.88  ? 638 LEU C CB  1 
ATOM   14043 C CG  . LEU C 1 638 ? 123.679 132.624 143.531 1.00 21.05  ? 638 LEU C CG  1 
ATOM   14044 C CD1 . LEU C 1 638 ? 125.117 132.377 143.112 1.00 22.24  ? 638 LEU C CD1 1 
ATOM   14045 C CD2 . LEU C 1 638 ? 123.126 131.351 144.154 1.00 17.90  ? 638 LEU C CD2 1 
ATOM   14046 N N   . ASN C 1 639 ? 122.521 136.227 142.810 1.00 24.10  ? 639 ASN C N   1 
ATOM   14047 C CA  . ASN C 1 639 ? 122.019 136.964 141.654 1.00 18.52  ? 639 ASN C CA  1 
ATOM   14048 C C   . ASN C 1 639 ? 122.916 138.158 141.281 1.00 18.20  ? 639 ASN C C   1 
ATOM   14049 O O   . ASN C 1 639 ? 123.252 138.324 140.118 1.00 23.90  ? 639 ASN C O   1 
ATOM   14050 C CB  . ASN C 1 639 ? 120.595 137.434 141.953 1.00 19.15  ? 639 ASN C CB  1 
ATOM   14051 C CG  . ASN C 1 639 ? 119.529 136.439 141.545 1.00 24.18  ? 639 ASN C CG  1 
ATOM   14052 O OD1 . ASN C 1 639 ? 119.267 136.201 140.384 1.00 31.22  ? 639 ASN C OD1 1 
ATOM   14053 N ND2 . ASN C 1 639 ? 118.869 135.811 142.477 1.00 30.95  ? 639 ASN C ND2 1 
ATOM   14054 N N   . MET C 1 640 ? 123.348 138.963 142.247 1.00 25.09  ? 640 MET C N   1 
ATOM   14055 C CA  . MET C 1 640 ? 124.262 140.083 142.041 1.00 18.01  ? 640 MET C CA  1 
ATOM   14056 C C   . MET C 1 640 ? 125.615 139.645 141.471 1.00 21.18  ? 640 MET C C   1 
ATOM   14057 O O   . MET C 1 640 ? 126.089 140.236 140.508 1.00 31.21  ? 640 MET C O   1 
ATOM   14058 C CB  . MET C 1 640 ? 124.398 140.836 143.372 1.00 24.23  ? 640 MET C CB  1 
ATOM   14059 C CG  . MET C 1 640 ? 125.300 142.071 143.328 1.00 26.88  ? 640 MET C CG  1 
ATOM   14060 S SD  . MET C 1 640 ? 127.057 141.844 143.657 1.00 40.73  ? 640 MET C SD  1 
ATOM   14061 C CE  . MET C 1 640 ? 127.042 141.377 145.399 1.00 27.25  ? 640 MET C CE  1 
ATOM   14062 N N   . LEU C 1 641 ? 126.218 138.580 142.001 1.00 24.58  ? 641 LEU C N   1 
ATOM   14063 C CA  . LEU C 1 641 ? 127.492 138.050 141.510 1.00 21.40  ? 641 LEU C CA  1 
ATOM   14064 C C   . LEU C 1 641 ? 127.381 137.490 140.091 1.00 19.67  ? 641 LEU C C   1 
ATOM   14065 O O   . LEU C 1 641 ? 128.215 137.792 139.247 1.00 26.59  ? 641 LEU C O   1 
ATOM   14066 C CB  . LEU C 1 641 ? 128.018 136.983 142.484 1.00 26.34  ? 641 LEU C CB  1 
ATOM   14067 C CG  . LEU C 1 641 ? 128.465 137.544 143.844 1.00 30.82  ? 641 LEU C CG  1 
ATOM   14068 C CD1 . LEU C 1 641 ? 128.731 136.406 144.820 1.00 27.86  ? 641 LEU C CD1 1 
ATOM   14069 C CD2 . LEU C 1 641 ? 129.722 138.390 143.730 1.00 24.89  ? 641 LEU C CD2 1 
ATOM   14070 N N   . ILE C 1 642 ? 126.347 136.706 139.805 1.00 24.89  ? 642 ILE C N   1 
ATOM   14071 C CA  . ILE C 1 642 ? 126.099 136.175 138.465 1.00 19.62  ? 642 ILE C CA  1 
ATOM   14072 C C   . ILE C 1 642 ? 125.800 137.306 137.467 1.00 19.82  ? 642 ILE C C   1 
ATOM   14073 O O   . ILE C 1 642 ? 126.360 137.310 136.374 1.00 32.42  ? 642 ILE C O   1 
ATOM   14074 C CB  . ILE C 1 642 ? 124.982 135.114 138.543 1.00 27.53  ? 642 ILE C CB  1 
ATOM   14075 C CG1 . ILE C 1 642 ? 125.436 133.811 139.241 1.00 21.68  ? 642 ILE C CG1 1 
ATOM   14076 C CG2 . ILE C 1 642 ? 124.421 134.793 137.162 1.00 26.55  ? 642 ILE C CG2 1 
ATOM   14077 C CD1 . ILE C 1 642 ? 126.483 132.972 138.506 1.00 23.53  ? 642 ILE C CD1 1 
ATOM   14078 N N   . ALA C 1 643 ? 125.007 138.313 137.834 1.00 23.64  ? 643 ALA C N   1 
ATOM   14079 C CA  . ALA C 1 643 ? 124.774 139.484 136.997 1.00 12.63  ? 643 ALA C CA  1 
ATOM   14080 C C   . ALA C 1 643 ? 126.047 140.313 136.741 1.00 18.95  ? 643 ALA C C   1 
ATOM   14081 O O   . ALA C 1 643 ? 126.217 140.818 135.637 1.00 35.66  ? 643 ALA C O   1 
ATOM   14082 C CB  . ALA C 1 643 ? 123.664 140.330 137.626 1.00 21.55  ? 643 ALA C CB  1 
ATOM   14083 N N   . LEU C 1 644 ? 126.979 140.425 137.696 1.00 30.99  ? 644 LEU C N   1 
ATOM   14084 C CA  . LEU C 1 644 ? 128.298 141.014 137.438 1.00 24.98  ? 644 LEU C CA  1 
ATOM   14085 C C   . LEU C 1 644 ? 129.124 140.186 136.461 1.00 24.51  ? 644 LEU C C   1 
ATOM   14086 O O   . LEU C 1 644 ? 129.724 140.763 135.563 1.00 34.03  ? 644 LEU C O   1 
ATOM   14087 C CB  . LEU C 1 644 ? 129.096 141.192 138.735 1.00 26.64  ? 644 LEU C CB  1 
ATOM   14088 C CG  . LEU C 1 644 ? 128.640 142.351 139.622 1.00 31.14  ? 644 LEU C CG  1 
ATOM   14089 C CD1 . LEU C 1 644 ? 129.474 142.326 140.894 1.00 27.84  ? 644 LEU C CD1 1 
ATOM   14090 C CD2 . LEU C 1 644 ? 128.840 143.710 138.955 1.00 34.04  ? 644 LEU C CD2 1 
ATOM   14091 N N   . MET C 1 645 ? 129.165 138.858 136.578 1.00 32.70  ? 645 MET C N   1 
ATOM   14092 C CA  . MET C 1 645 ? 129.882 138.007 135.623 1.00 28.86  ? 645 MET C CA  1 
ATOM   14093 C C   . MET C 1 645 ? 129.338 138.152 134.198 1.00 31.61  ? 645 MET C C   1 
ATOM   14094 O O   . MET C 1 645 ? 130.120 138.384 133.283 1.00 37.35  ? 645 MET C O   1 
ATOM   14095 C CB  . MET C 1 645 ? 129.842 136.544 136.055 1.00 29.17  ? 645 MET C CB  1 
ATOM   14096 C CG  . MET C 1 645 ? 130.650 136.303 137.322 1.00 32.65  ? 645 MET C CG  1 
ATOM   14097 S SD  . MET C 1 645 ? 130.450 134.641 137.997 1.00 52.21  ? 645 MET C SD  1 
ATOM   14098 C CE  . MET C 1 645 ? 130.954 134.984 139.700 1.00 37.43  ? 645 MET C CE  1 
ATOM   14099 N N   . SER C 1 646 ? 128.015 138.113 134.002 1.00 33.02  ? 646 SER C N   1 
ATOM   14100 C CA  . SER C 1 646 ? 127.375 138.319 132.697 1.00 32.03  ? 646 SER C CA  1 
ATOM   14101 C C   . SER C 1 646 ? 127.717 139.671 132.059 1.00 37.47  ? 646 SER C C   1 
ATOM   14102 O O   . SER C 1 646 ? 127.761 139.782 130.840 1.00 45.37  ? 646 SER C O   1 
ATOM   14103 C CB  . SER C 1 646 ? 125.850 138.235 132.816 1.00 27.85  ? 646 SER C CB  1 
ATOM   14104 O OG  . SER C 1 646 ? 125.428 137.010 133.374 1.00 36.36  ? 646 SER C OG  1 
ATOM   14105 N N   . GLU C 1 647 ? 127.956 140.715 132.846 1.00 36.15  ? 647 GLU C N   1 
ATOM   14106 C CA  . GLU C 1 647 ? 128.307 142.041 132.332 1.00 36.22  ? 647 GLU C CA  1 
ATOM   14107 C C   . GLU C 1 647 ? 129.817 142.226 132.088 1.00 39.21  ? 647 GLU C C   1 
ATOM   14108 O O   . GLU C 1 647 ? 130.220 142.940 131.174 1.00 44.20  ? 647 GLU C O   1 
ATOM   14109 C CB  . GLU C 1 647 ? 127.764 143.088 133.313 1.00 35.63  ? 647 GLU C CB  1 
ATOM   14110 C CG  . GLU C 1 647 ? 127.995 144.551 132.907 1.00 45.33  ? 647 GLU C CG  1 
ATOM   14111 C CD  . GLU C 1 647 ? 127.085 145.056 131.772 1.00 50.47  ? 647 GLU C CD  1 
ATOM   14112 O OE1 . GLU C 1 647 ? 126.813 144.313 130.803 1.00 50.08  ? 647 GLU C OE1 1 
ATOM   14113 O OE2 . GLU C 1 647 ? 126.636 146.219 131.858 1.00 47.95  ? 647 GLU C OE2 1 
ATOM   14114 N N   . THR C 1 648 ? 130.668 141.595 132.898 1.00 35.61  ? 648 THR C N   1 
ATOM   14115 C CA  . THR C 1 648 ? 132.106 141.903 132.959 1.00 34.31  ? 648 THR C CA  1 
ATOM   14116 C C   . THR C 1 648 ? 133.025 140.869 132.305 1.00 35.08  ? 648 THR C C   1 
ATOM   14117 O O   . THR C 1 648 ? 134.142 141.225 131.935 1.00 40.24  ? 648 THR C O   1 
ATOM   14118 C CB  . THR C 1 648 ? 132.556 142.135 134.411 1.00 36.55  ? 648 THR C CB  1 
ATOM   14119 O OG1 . THR C 1 648 ? 132.308 141.008 135.203 1.00 40.46  ? 648 THR C OG1 1 
ATOM   14120 C CG2 . THR C 1 648 ? 131.904 143.341 135.084 1.00 28.28  ? 648 THR C CG2 1 
ATOM   14121 N N   . VAL C 1 649 ? 132.599 139.615 132.131 1.00 36.00  ? 649 VAL C N   1 
ATOM   14122 C CA  . VAL C 1 649 ? 133.440 138.495 131.657 1.00 38.52  ? 649 VAL C CA  1 
ATOM   14123 C C   . VAL C 1 649 ? 133.029 138.086 130.232 1.00 38.34  ? 649 VAL C C   1 
ATOM   14124 O O   . VAL C 1 649 ? 132.548 136.988 129.988 1.00 40.52  ? 649 VAL C O   1 
ATOM   14125 C CB  . VAL C 1 649 ? 133.457 137.325 132.674 1.00 39.25  ? 649 VAL C CB  1 
ATOM   14126 C CG1 . VAL C 1 649 ? 134.508 136.258 132.331 1.00 39.42  ? 649 VAL C CG1 1 
ATOM   14127 C CG2 . VAL C 1 649 ? 133.795 137.797 134.096 1.00 31.13  ? 649 VAL C CG2 1 
ATOM   14128 N N   . ASN C 1 650 ? 133.174 139.015 129.284 1.00 42.21  ? 650 ASN C N   1 
ATOM   14129 C CA  . ASN C 1 650 ? 132.657 138.928 127.910 1.00 39.29  ? 650 ASN C CA  1 
ATOM   14130 C C   . ASN C 1 650 ? 133.726 138.851 126.800 1.00 41.39  ? 650 ASN C C   1 
ATOM   14131 O O   . ASN C 1 650 ? 133.410 139.042 125.631 1.00 43.19  ? 650 ASN C O   1 
ATOM   14132 C CB  . ASN C 1 650 ? 131.644 140.070 127.693 1.00 44.19  ? 650 ASN C CB  1 
ATOM   14133 C CG  . ASN C 1 650 ? 130.322 139.803 128.393 1.00 48.36  ? 650 ASN C CG  1 
ATOM   14134 O OD1 . ASN C 1 650 ? 129.733 138.743 128.259 1.00 47.24  ? 650 ASN C OD1 1 
ATOM   14135 N ND2 . ASN C 1 650 ? 129.799 140.736 129.139 1.00 44.72  ? 650 ASN C ND2 1 
ATOM   14136 N N   . HIS C 1 651 ? 134.985 138.573 127.140 1.00 43.37  ? 651 HIS C N   1 
ATOM   14137 C CA  . HIS C 1 651 ? 136.116 138.392 126.202 1.00 39.98  ? 651 HIS C CA  1 
ATOM   14138 C C   . HIS C 1 651 ? 136.440 139.591 125.300 1.00 42.66  ? 651 HIS C C   1 
ATOM   14139 O O   . HIS C 1 651 ? 137.126 139.449 124.287 1.00 50.25  ? 651 HIS C O   1 
ATOM   14140 C CB  . HIS C 1 651 ? 135.864 137.138 125.347 1.00 42.40  ? 651 HIS C CB  1 
ATOM   14141 C CG  . HIS C 1 651 ? 135.465 135.945 126.150 1.00 41.23  ? 651 HIS C CG  1 
ATOM   14142 N ND1 . HIS C 1 651 ? 136.387 135.032 126.625 1.00 44.34  ? 651 HIS C ND1 1 
ATOM   14143 C CD2 . HIS C 1 651 ? 134.255 135.517 126.570 1.00 44.88  ? 651 HIS C CD2 1 
ATOM   14144 C CE1 . HIS C 1 651 ? 135.761 134.090 127.300 1.00 43.64  ? 651 HIS C CE1 1 
ATOM   14145 N NE2 . HIS C 1 651 ? 134.451 134.364 127.281 1.00 42.42  ? 651 HIS C NE2 1 
ATOM   14146 N N   . VAL C 1 652 ? 135.979 140.787 125.664 1.00 47.14  ? 652 VAL C N   1 
ATOM   14147 C CA  . VAL C 1 652 ? 136.399 142.040 125.028 1.00 44.64  ? 652 VAL C CA  1 
ATOM   14148 C C   . VAL C 1 652 ? 137.898 142.264 125.236 1.00 46.23  ? 652 VAL C C   1 
ATOM   14149 O O   . VAL C 1 652 ? 138.463 141.838 126.246 1.00 45.90  ? 652 VAL C O   1 
ATOM   14150 C CB  . VAL C 1 652 ? 135.574 143.239 125.522 1.00 45.38  ? 652 VAL C CB  1 
ATOM   14151 C CG1 . VAL C 1 652 ? 134.090 143.055 125.172 1.00 43.86  ? 652 VAL C CG1 1 
ATOM   14152 C CG2 . VAL C 1 652 ? 135.697 143.495 127.028 1.00 47.71  ? 652 VAL C CG2 1 
ATOM   14153 N N   . ALA C 1 653 ? 138.558 142.914 124.283 1.00 51.36  ? 653 ALA C N   1 
ATOM   14154 C CA  . ALA C 1 653 ? 139.994 143.171 124.357 1.00 51.38  ? 653 ALA C CA  1 
ATOM   14155 C C   . ALA C 1 653 ? 140.367 143.999 125.603 1.00 53.52  ? 653 ALA C C   1 
ATOM   14156 O O   . ALA C 1 653 ? 139.665 144.937 125.986 1.00 52.14  ? 653 ALA C O   1 
ATOM   14157 C CB  . ALA C 1 653 ? 140.441 143.844 123.059 1.00 49.84  ? 653 ALA C CB  1 
ATOM   14158 N N   . ASP C 1 654 ? 141.485 143.652 126.236 1.00 52.55  ? 654 ASP C N   1 
ATOM   14159 C CA  . ASP C 1 654 ? 141.979 144.305 127.449 1.00 50.58  ? 654 ASP C CA  1 
ATOM   14160 C C   . ASP C 1 654 ? 142.579 145.693 127.154 1.00 51.43  ? 654 ASP C C   1 
ATOM   14161 O O   . ASP C 1 654 ? 143.774 145.848 126.912 1.00 51.33  ? 654 ASP C O   1 
ATOM   14162 C CB  . ASP C 1 654 ? 142.989 143.363 128.123 1.00 52.20  ? 654 ASP C CB  1 
ATOM   14163 C CG  . ASP C 1 654 ? 143.570 143.950 129.408 1.00 57.76  ? 654 ASP C CG  1 
ATOM   14164 O OD1 . ASP C 1 654 ? 142.961 144.880 129.989 1.00 58.12  ? 654 ASP C OD1 1 
ATOM   14165 O OD2 . ASP C 1 654 ? 144.653 143.502 129.831 1.00 57.40  ? 654 ASP C OD2 1 
ATOM   14166 N N   . ASN C 1 655 ? 141.741 146.726 127.180 1.00 45.82  ? 655 ASN C N   1 
ATOM   14167 C CA  . ASN C 1 655 ? 142.104 148.127 126.943 1.00 42.19  ? 655 ASN C CA  1 
ATOM   14168 C C   . ASN C 1 655 ? 142.787 148.819 128.143 1.00 40.98  ? 655 ASN C C   1 
ATOM   14169 O O   . ASN C 1 655 ? 142.940 150.041 128.159 1.00 44.53  ? 655 ASN C O   1 
ATOM   14170 C CB  . ASN C 1 655 ? 140.862 148.884 126.444 1.00 40.98  ? 655 ASN C CB  1 
ATOM   14171 C CG  . ASN C 1 655 ? 139.719 148.960 127.440 1.00 45.38  ? 655 ASN C CG  1 
ATOM   14172 O OD1 . ASN C 1 655 ? 139.807 148.539 128.580 1.00 50.39  ? 655 ASN C OD1 1 
ATOM   14173 N ND2 . ASN C 1 655 ? 138.584 149.472 127.032 1.00 44.54  ? 655 ASN C ND2 1 
ATOM   14174 N N   . SER C 1 656 ? 143.218 148.072 129.161 1.00 42.05  ? 656 SER C N   1 
ATOM   14175 C CA  . SER C 1 656 ? 143.796 148.642 130.379 1.00 38.78  ? 656 SER C CA  1 
ATOM   14176 C C   . SER C 1 656 ? 145.141 149.338 130.152 1.00 37.66  ? 656 SER C C   1 
ATOM   14177 O O   . SER C 1 656 ? 145.395 150.362 130.779 1.00 41.50  ? 656 SER C O   1 
ATOM   14178 C CB  . SER C 1 656 ? 143.916 147.562 131.454 1.00 37.31  ? 656 SER C CB  1 
ATOM   14179 O OG  . SER C 1 656 ? 144.714 146.505 130.986 1.00 45.08  ? 656 SER C OG  1 
ATOM   14180 N N   . TRP C 1 657 ? 145.966 148.870 129.205 1.00 28.79  ? 657 TRP C N   1 
ATOM   14181 C CA  . TRP C 1 657 ? 147.201 149.558 128.795 1.00 25.07  ? 657 TRP C CA  1 
ATOM   14182 C C   . TRP C 1 657 ? 146.929 150.957 128.228 1.00 28.34  ? 657 TRP C C   1 
ATOM   14183 O O   . TRP C 1 657 ? 147.574 151.921 128.627 1.00 34.27  ? 657 TRP C O   1 
ATOM   14184 C CB  . TRP C 1 657 ? 147.977 148.689 127.801 1.00 21.15  ? 657 TRP C CB  1 
ATOM   14185 C CG  . TRP C 1 657 ? 149.210 149.322 127.228 1.00 26.85  ? 657 TRP C CG  1 
ATOM   14186 C CD1 . TRP C 1 657 ? 150.458 149.234 127.746 1.00 27.87  ? 657 TRP C CD1 1 
ATOM   14187 C CD2 . TRP C 1 657 ? 149.346 150.138 126.031 1.00 30.03  ? 657 TRP C CD2 1 
ATOM   14188 N NE1 . TRP C 1 657 ? 151.336 149.972 126.983 1.00 29.05  ? 657 TRP C NE1 1 
ATOM   14189 C CE2 . TRP C 1 657 ? 150.703 150.559 125.910 1.00 31.31  ? 657 TRP C CE2 1 
ATOM   14190 C CE3 . TRP C 1 657 ? 148.467 150.531 124.995 1.00 24.84  ? 657 TRP C CE3 1 
ATOM   14191 C CZ2 . TRP C 1 657 ? 151.157 151.351 124.852 1.00 29.13  ? 657 TRP C CZ2 1 
ATOM   14192 C CZ3 . TRP C 1 657 ? 148.920 151.303 123.918 1.00 28.94  ? 657 TRP C CZ3 1 
ATOM   14193 C CH2 . TRP C 1 657 ? 150.255 151.736 123.848 1.00 31.67  ? 657 TRP C CH2 1 
ATOM   14194 N N   . SER C 1 658 ? 145.925 151.096 127.365 1.00 33.66  ? 658 SER C N   1 
ATOM   14195 C CA  . SER C 1 658 ? 145.515 152.375 126.789 1.00 21.31  ? 658 SER C CA  1 
ATOM   14196 C C   . SER C 1 658 ? 144.958 153.331 127.841 1.00 25.95  ? 658 SER C C   1 
ATOM   14197 O O   . SER C 1 658 ? 145.288 154.514 127.853 1.00 31.89  ? 658 SER C O   1 
ATOM   14198 C CB  . SER C 1 658 ? 144.437 152.154 125.723 1.00 27.71  ? 658 SER C CB  1 
ATOM   14199 O OG  . SER C 1 658 ? 144.858 151.178 124.792 1.00 41.52  ? 658 SER C OG  1 
ATOM   14200 N N   . ILE C 1 659 ? 144.124 152.838 128.760 1.00 29.32  ? 659 ILE C N   1 
ATOM   14201 C CA  . ILE C 1 659 ? 143.558 153.656 129.842 1.00 31.60  ? 659 ILE C CA  1 
ATOM   14202 C C   . ILE C 1 659 ? 144.651 154.115 130.819 1.00 21.00  ? 659 ILE C C   1 
ATOM   14203 O O   . ILE C 1 659 ? 144.631 155.254 131.271 1.00 23.27  ? 659 ILE C O   1 
ATOM   14204 C CB  . ILE C 1 659 ? 142.409 152.894 130.528 1.00 28.00  ? 659 ILE C CB  1 
ATOM   14205 C CG1 . ILE C 1 659 ? 141.207 152.746 129.581 1.00 26.93  ? 659 ILE C CG1 1 
ATOM   14206 C CG2 . ILE C 1 659 ? 141.967 153.580 131.832 1.00 27.78  ? 659 ILE C CG2 1 
ATOM   14207 C CD1 . ILE C 1 659 ? 140.176 151.724 130.047 1.00 27.73  ? 659 ILE C CD1 1 
ATOM   14208 N N   . TRP C 1 660 ? 145.663 153.297 131.086 1.00 17.28  ? 660 TRP C N   1 
ATOM   14209 C CA  . TRP C 1 660 ? 146.857 153.716 131.807 1.00 10.55  ? 660 TRP C CA  1 
ATOM   14210 C C   . TRP C 1 660 ? 147.711 154.744 131.044 1.00 22.08  ? 660 TRP C C   1 
ATOM   14211 O O   . TRP C 1 660 ? 148.159 155.724 131.635 1.00 29.40  ? 660 TRP C O   1 
ATOM   14212 C CB  . TRP C 1 660 ? 147.652 152.474 132.186 1.00 17.93  ? 660 TRP C CB  1 
ATOM   14213 C CG  . TRP C 1 660 ? 149.017 152.755 132.709 1.00 26.63  ? 660 TRP C CG  1 
ATOM   14214 C CD1 . TRP C 1 660 ? 149.307 153.377 133.870 1.00 15.35  ? 660 TRP C CD1 1 
ATOM   14215 C CD2 . TRP C 1 660 ? 150.287 152.534 132.039 1.00 23.18  ? 660 TRP C CD2 1 
ATOM   14216 N NE1 . TRP C 1 660 ? 150.674 153.488 133.995 1.00 16.84  ? 660 TRP C NE1 1 
ATOM   14217 C CE2 . TRP C 1 660 ? 151.326 152.963 132.906 1.00 21.55  ? 660 TRP C CE2 1 
ATOM   14218 C CE3 . TRP C 1 660 ? 150.660 152.007 130.786 1.00 25.93  ? 660 TRP C CE3 1 
ATOM   14219 C CZ2 . TRP C 1 660 ? 152.679 152.819 132.573 1.00 19.79  ? 660 TRP C CZ2 1 
ATOM   14220 C CZ3 . TRP C 1 660 ? 152.010 151.890 130.428 1.00 28.74  ? 660 TRP C CZ3 1 
ATOM   14221 C CH2 . TRP C 1 660 ? 153.018 152.289 131.320 1.00 28.98  ? 660 TRP C CH2 1 
ATOM   14222 N N   . LYS C 1 661 ? 147.889 154.617 129.723 1.00 26.49  ? 661 LYS C N   1 
ATOM   14223 C CA  . LYS C 1 661 ? 148.541 155.660 128.910 1.00 12.24  ? 661 LYS C CA  1 
ATOM   14224 C C   . LYS C 1 661 ? 147.780 156.986 128.959 1.00 13.22  ? 661 LYS C C   1 
ATOM   14225 O O   . LYS C 1 661 ? 148.412 158.036 128.991 1.00 23.78  ? 661 LYS C O   1 
ATOM   14226 C CB  . LYS C 1 661 ? 148.721 155.196 127.456 1.00 18.81  ? 661 LYS C CB  1 
ATOM   14227 C CG  . LYS C 1 661 ? 149.800 154.134 127.232 1.00 13.68  ? 661 LYS C CG  1 
ATOM   14228 C CD  . LYS C 1 661 ? 151.199 154.560 127.688 1.00 16.52  ? 661 LYS C CD  1 
ATOM   14229 C CE  . LYS C 1 661 ? 152.230 153.598 127.097 1.00 27.22  ? 661 LYS C CE  1 
ATOM   14230 N NZ  . LYS C 1 661 ? 153.602 153.840 127.611 1.00 30.44  ? 661 LYS C NZ  1 
ATOM   14231 N N   . LEU C 1 662 ? 146.453 156.971 129.056 1.00 16.36  ? 662 LEU C N   1 
ATOM   14232 C CA  . LEU C 1 662 ? 145.647 158.165 129.313 1.00 12.57  ? 662 LEU C CA  1 
ATOM   14233 C C   . LEU C 1 662 ? 145.842 158.734 130.730 1.00 15.77  ? 662 LEU C C   1 
ATOM   14234 O O   . LEU C 1 662 ? 145.951 159.944 130.879 1.00 28.76  ? 662 LEU C O   1 
ATOM   14235 C CB  . LEU C 1 662 ? 144.181 157.852 128.984 1.00 16.98  ? 662 LEU C CB  1 
ATOM   14236 C CG  . LEU C 1 662 ? 143.195 159.007 129.219 1.00 20.55  ? 662 LEU C CG  1 
ATOM   14237 C CD1 . LEU C 1 662 ? 143.433 160.193 128.296 1.00 16.72  ? 662 LEU C CD1 1 
ATOM   14238 C CD2 . LEU C 1 662 ? 141.788 158.503 128.983 1.00 14.86  ? 662 LEU C CD2 1 
ATOM   14239 N N   . GLN C 1 663 ? 145.968 157.909 131.768 1.00 25.38  ? 663 GLN C N   1 
ATOM   14240 C CA  . GLN C 1 663 ? 146.322 158.379 133.115 1.00 9.62   ? 663 GLN C CA  1 
ATOM   14241 C C   . GLN C 1 663 ? 147.687 159.064 133.155 1.00 15.61  ? 663 GLN C C   1 
ATOM   14242 O O   . GLN C 1 663 ? 147.818 160.139 133.742 1.00 25.43  ? 663 GLN C O   1 
ATOM   14243 C CB  . GLN C 1 663 ? 146.331 157.219 134.109 1.00 15.15  ? 663 GLN C CB  1 
ATOM   14244 C CG  . GLN C 1 663 ? 144.942 156.675 134.419 1.00 12.53  ? 663 GLN C CG  1 
ATOM   14245 C CD  . GLN C 1 663 ? 145.009 155.486 135.360 1.00 16.31  ? 663 GLN C CD  1 
ATOM   14246 O OE1 . GLN C 1 663 ? 146.065 154.964 135.668 1.00 30.67  ? 663 GLN C OE1 1 
ATOM   14247 N NE2 . GLN C 1 663 ? 143.887 155.037 135.857 1.00 24.77  ? 663 GLN C NE2 1 
ATOM   14248 N N   . LYS C 1 664 ? 148.692 158.477 132.495 1.00 24.83  ? 664 LYS C N   1 
ATOM   14249 C CA  . LYS C 1 664 ? 150.003 159.101 132.289 1.00 4.45   ? 664 LYS C CA  1 
ATOM   14250 C C   . LYS C 1 664 ? 149.909 160.411 131.519 1.00 17.62  ? 664 LYS C C   1 
ATOM   14251 O O   . LYS C 1 664 ? 150.537 161.369 131.935 1.00 34.20  ? 664 LYS C O   1 
ATOM   14252 C CB  . LYS C 1 664 ? 150.963 158.134 131.596 1.00 15.21  ? 664 LYS C CB  1 
ATOM   14253 C CG  . LYS C 1 664 ? 151.544 157.116 132.575 1.00 15.92  ? 664 LYS C CG  1 
ATOM   14254 C CD  . LYS C 1 664 ? 152.755 156.408 131.965 1.00 17.77  ? 664 LYS C CD  1 
ATOM   14255 C CE  . LYS C 1 664 ? 153.617 155.870 133.111 1.00 33.85  ? 664 LYS C CE  1 
ATOM   14256 N NZ  . LYS C 1 664 ? 154.921 155.338 132.625 1.00 37.07  ? 664 LYS C NZ  1 
ATOM   14257 N N   . ALA C 1 665 ? 149.092 160.493 130.471 1.00 20.17  ? 665 ALA C N   1 
ATOM   14258 C CA  . ALA C 1 665 ? 148.862 161.719 129.715 1.00 7.71   ? 665 ALA C CA  1 
ATOM   14259 C C   . ALA C 1 665 ? 148.277 162.840 130.579 1.00 16.96  ? 665 ALA C C   1 
ATOM   14260 O O   . ALA C 1 665 ? 148.807 163.943 130.581 1.00 26.32  ? 665 ALA C O   1 
ATOM   14261 C CB  . ALA C 1 665 ? 147.971 161.407 128.510 1.00 10.43  ? 665 ALA C CB  1 
ATOM   14262 N N   . ILE C 1 666 ? 147.237 162.567 131.365 1.00 18.55  ? 666 ILE C N   1 
ATOM   14263 C CA  . ILE C 1 666 ? 146.629 163.529 132.296 1.00 20.00  ? 666 ILE C CA  1 
ATOM   14264 C C   . ILE C 1 666 ? 147.642 164.001 133.347 1.00 18.44  ? 666 ILE C C   1 
ATOM   14265 O O   . ILE C 1 666 ? 147.769 165.194 133.599 1.00 27.29  ? 666 ILE C O   1 
ATOM   14266 C CB  . ILE C 1 666 ? 145.372 162.889 132.932 1.00 18.56  ? 666 ILE C CB  1 
ATOM   14267 C CG1 . ILE C 1 666 ? 144.257 162.760 131.877 1.00 20.01  ? 666 ILE C CG1 1 
ATOM   14268 C CG2 . ILE C 1 666 ? 144.857 163.681 134.140 1.00 22.12  ? 666 ILE C CG2 1 
ATOM   14269 C CD1 . ILE C 1 666 ? 143.214 161.698 132.219 1.00 27.66  ? 666 ILE C CD1 1 
ATOM   14270 N N   . SER C 1 667 ? 148.362 163.049 133.947 1.00 25.73  ? 667 SER C N   1 
ATOM   14271 C CA  . SER C 1 667 ? 149.393 163.402 134.958 1.00 19.55  ? 667 SER C CA  1 
ATOM   14272 C C   . SER C 1 667 ? 150.428 164.339 134.330 1.00 18.07  ? 667 SER C C   1 
ATOM   14273 O O   . SER C 1 667 ? 150.720 165.389 134.935 1.00 31.07  ? 667 SER C O   1 
ATOM   14274 C CB  . SER C 1 667 ? 150.044 162.164 135.518 1.00 19.35  ? 667 SER C CB  1 
ATOM   14275 O OG  . SER C 1 667 ? 151.098 162.507 136.405 1.00 40.37  ? 667 SER C OG  1 
ATOM   14276 N N   . VAL C 1 668 ? 150.956 163.968 133.160 1.00 19.77  ? 668 VAL C N   1 
ATOM   14277 C CA  . VAL C 1 668 ? 151.998 164.796 132.479 1.00 20.02  ? 668 VAL C CA  1 
ATOM   14278 C C   . VAL C 1 668 ? 151.425 166.186 132.188 1.00 21.86  ? 668 VAL C C   1 
ATOM   14279 O O   . VAL C 1 668 ? 152.037 167.177 132.635 1.00 32.11  ? 668 VAL C O   1 
ATOM   14280 C CB  . VAL C 1 668 ? 152.497 164.117 131.189 1.00 22.81  ? 668 VAL C CB  1 
ATOM   14281 C CG1 . VAL C 1 668 ? 153.248 165.089 130.292 1.00 28.11  ? 668 VAL C CG1 1 
ATOM   14282 C CG2 . VAL C 1 668 ? 153.347 162.891 131.486 1.00 19.96  ? 668 VAL C CG2 1 
ATOM   14283 N N   . LEU C 1 669 ? 150.300 166.257 131.470 1.00 26.68  ? 669 LEU C N   1 
ATOM   14284 C CA  . LEU C 1 669 ? 149.743 167.549 131.093 1.00 21.37  ? 669 LEU C CA  1 
ATOM   14285 C C   . LEU C 1 669 ? 149.493 168.448 132.307 1.00 27.76  ? 669 LEU C C   1 
ATOM   14286 O O   . LEU C 1 669 ? 149.528 169.665 132.173 1.00 34.29  ? 669 LEU C O   1 
ATOM   14287 C CB  . LEU C 1 669 ? 148.472 167.313 130.269 1.00 24.50  ? 669 LEU C CB  1 
ATOM   14288 C CG  . LEU C 1 669 ? 148.764 166.664 128.904 1.00 25.97  ? 669 LEU C CG  1 
ATOM   14289 C CD1 . LEU C 1 669 ? 147.494 166.066 128.320 1.00 24.15  ? 669 LEU C CD1 1 
ATOM   14290 C CD2 . LEU C 1 669 ? 149.314 167.669 127.903 1.00 26.69  ? 669 LEU C CD2 1 
ATOM   14291 N N   . GLU C 1 670 ? 149.303 167.882 133.500 1.00 35.20  ? 670 GLU C N   1 
ATOM   14292 C CA  . GLU C 1 670 ? 149.311 168.627 134.755 1.00 22.19  ? 670 GLU C CA  1 
ATOM   14293 C C   . GLU C 1 670 ? 150.717 169.027 135.213 1.00 31.54  ? 670 GLU C C   1 
ATOM   14294 O O   . GLU C 1 670 ? 150.955 170.208 135.459 1.00 37.59  ? 670 GLU C O   1 
ATOM   14295 C CB  . GLU C 1 670 ? 148.581 167.821 135.837 1.00 30.07  ? 670 GLU C CB  1 
ATOM   14296 C CG  . GLU C 1 670 ? 147.066 168.014 135.734 1.00 36.49  ? 670 GLU C CG  1 
ATOM   14297 C CD  . GLU C 1 670 ? 146.683 169.484 135.939 1.00 43.32  ? 670 GLU C CD  1 
ATOM   14298 O OE1 . GLU C 1 670 ? 147.150 170.102 136.918 1.00 43.48  ? 670 GLU C OE1 1 
ATOM   14299 O OE2 . GLU C 1 670 ? 145.950 170.063 135.106 1.00 44.29  ? 670 GLU C OE2 1 
ATOM   14300 N N   . MET C 1 671 ? 151.662 168.084 135.273 1.00 30.15  ? 671 MET C N   1 
ATOM   14301 C CA  . MET C 1 671 ? 153.050 168.345 135.662 1.00 23.28  ? 671 MET C CA  1 
ATOM   14302 C C   . MET C 1 671 ? 153.771 169.361 134.773 1.00 32.08  ? 671 MET C C   1 
ATOM   14303 O O   . MET C 1 671 ? 154.597 170.117 135.273 1.00 35.75  ? 671 MET C O   1 
ATOM   14304 C CB  . MET C 1 671 ? 153.851 167.046 135.659 1.00 26.41  ? 671 MET C CB  1 
ATOM   14305 C CG  . MET C 1 671 ? 153.527 166.143 136.841 1.00 27.40  ? 671 MET C CG  1 
ATOM   14306 S SD  . MET C 1 671 ? 154.687 164.774 136.988 1.00 31.61  ? 671 MET C SD  1 
ATOM   14307 C CE  . MET C 1 671 ? 154.241 163.764 135.559 1.00 24.18  ? 671 MET C CE  1 
ATOM   14308 N N   . GLU C 1 672 ? 153.457 169.429 133.478 1.00 34.85  ? 672 GLU C N   1 
ATOM   14309 C CA  . GLU C 1 672 ? 154.021 170.421 132.561 1.00 27.38  ? 672 GLU C CA  1 
ATOM   14310 C C   . GLU C 1 672 ? 153.734 171.877 132.966 1.00 34.76  ? 672 GLU C C   1 
ATOM   14311 O O   . GLU C 1 672 ? 154.527 172.749 132.616 1.00 36.70  ? 672 GLU C O   1 
ATOM   14312 C CB  . GLU C 1 672 ? 153.502 170.186 131.137 1.00 34.24  ? 672 GLU C CB  1 
ATOM   14313 C CG  . GLU C 1 672 ? 154.283 169.099 130.399 1.00 32.34  ? 672 GLU C CG  1 
ATOM   14314 C CD  . GLU C 1 672 ? 153.874 169.018 128.924 1.00 40.21  ? 672 GLU C CD  1 
ATOM   14315 O OE1 . GLU C 1 672 ? 152.670 168.914 128.618 1.00 37.22  ? 672 GLU C OE1 1 
ATOM   14316 O OE2 . GLU C 1 672 ? 154.757 169.105 128.043 1.00 49.10  ? 672 GLU C OE2 1 
ATOM   14317 N N   . ASN C 1 673 ? 152.662 172.155 133.717 1.00 40.12  ? 673 ASN C N   1 
ATOM   14318 C CA  . ASN C 1 673 ? 152.375 173.491 134.266 1.00 39.97  ? 673 ASN C CA  1 
ATOM   14319 C C   . ASN C 1 673 ? 153.228 173.847 135.498 1.00 41.63  ? 673 ASN C C   1 
ATOM   14320 O O   . ASN C 1 673 ? 153.244 175.000 135.925 1.00 46.28  ? 673 ASN C O   1 
ATOM   14321 C CB  . ASN C 1 673 ? 150.887 173.591 134.640 1.00 37.24  ? 673 ASN C CB  1 
ATOM   14322 C CG  . ASN C 1 673 ? 149.954 173.284 133.490 1.00 40.21  ? 673 ASN C CG  1 
ATOM   14323 O OD1 . ASN C 1 673 ? 150.082 173.801 132.391 1.00 43.54  ? 673 ASN C OD1 1 
ATOM   14324 N ND2 . ASN C 1 673 ? 148.990 172.430 133.699 1.00 42.89  ? 673 ASN C ND2 1 
ATOM   14325 N N   . GLY C 1 674 ? 153.916 172.873 136.100 1.00 37.14  ? 674 GLY C N   1 
ATOM   14326 C CA  . GLY C 1 674 ? 154.573 173.012 137.393 1.00 36.85  ? 674 GLY C CA  1 
ATOM   14327 C C   . GLY C 1 674 ? 153.586 173.120 138.553 1.00 32.26  ? 674 GLY C C   1 
ATOM   14328 O O   . GLY C 1 674 ? 152.450 172.660 138.477 1.00 38.21  ? 674 GLY C O   1 
ATOM   14329 N N   . TYR C 1 675 ? 154.032 173.706 139.653 1.00 37.80  ? 675 TYR C N   1 
ATOM   14330 C CA  . TYR C 1 675 ? 153.251 173.844 140.884 1.00 39.83  ? 675 TYR C CA  1 
ATOM   14331 C C   . TYR C 1 675 ? 152.469 175.161 140.958 1.00 37.77  ? 675 TYR C C   1 
ATOM   14332 O O   . TYR C 1 675 ? 152.845 176.141 140.311 1.00 48.94  ? 675 TYR C O   1 
ATOM   14333 C CB  . TYR C 1 675 ? 154.195 173.693 142.076 1.00 33.74  ? 675 TYR C CB  1 
ATOM   14334 C CG  . TYR C 1 675 ? 155.032 172.433 142.045 1.00 34.83  ? 675 TYR C CG  1 
ATOM   14335 C CD1 . TYR C 1 675 ? 154.403 171.178 142.145 1.00 33.98  ? 675 TYR C CD1 1 
ATOM   14336 C CD2 . TYR C 1 675 ? 156.427 172.507 141.915 1.00 39.07  ? 675 TYR C CD2 1 
ATOM   14337 C CE1 . TYR C 1 675 ? 155.165 170.001 142.106 1.00 32.58  ? 675 TYR C CE1 1 
ATOM   14338 C CE2 . TYR C 1 675 ? 157.195 171.328 141.893 1.00 38.54  ? 675 TYR C CE2 1 
ATOM   14339 C CZ  . TYR C 1 675 ? 156.566 170.075 141.985 1.00 34.97  ? 675 TYR C CZ  1 
ATOM   14340 O OH  . TYR C 1 675 ? 157.316 168.945 141.960 1.00 34.66  ? 675 TYR C OH  1 
ATOM   14341 N N   . TRP C 1 676 ? 151.440 175.226 141.804 1.00 33.06  ? 676 TRP C N   1 
ATOM   14342 C CA  . TRP C 1 676 ? 150.579 176.409 141.958 1.00 32.98  ? 676 TRP C CA  1 
ATOM   14343 C C   . TRP C 1 676 ? 151.360 177.683 142.317 1.00 36.33  ? 676 TRP C C   1 
ATOM   14344 O O   . TRP C 1 676 ? 151.003 178.773 141.875 1.00 45.04  ? 676 TRP C O   1 
ATOM   14345 C CB  . TRP C 1 676 ? 149.486 176.113 143.000 1.00 34.51  ? 676 TRP C CB  1 
ATOM   14346 C CG  . TRP C 1 676 ? 149.922 175.882 144.417 1.00 34.40  ? 676 TRP C CG  1 
ATOM   14347 C CD1 . TRP C 1 676 ? 150.194 174.681 144.970 1.00 35.81  ? 676 TRP C CD1 1 
ATOM   14348 C CD2 . TRP C 1 676 ? 150.175 176.862 145.471 1.00 37.28  ? 676 TRP C CD2 1 
ATOM   14349 N NE1 . TRP C 1 676 ? 150.588 174.845 146.280 1.00 33.64  ? 676 TRP C NE1 1 
ATOM   14350 C CE2 . TRP C 1 676 ? 150.632 176.172 146.631 1.00 35.62  ? 676 TRP C CE2 1 
ATOM   14351 C CE3 . TRP C 1 676 ? 150.093 178.268 145.559 1.00 38.08  ? 676 TRP C CE3 1 
ATOM   14352 C CZ2 . TRP C 1 676 ? 151.017 176.838 147.799 1.00 40.63  ? 676 TRP C CZ2 1 
ATOM   14353 C CZ3 . TRP C 1 676 ? 150.481 178.947 146.728 1.00 36.13  ? 676 TRP C CZ3 1 
ATOM   14354 C CH2 . TRP C 1 676 ? 150.953 178.238 147.841 1.00 40.41  ? 676 TRP C CH2 1 
ATOM   14355 N N   . TRP C 1 677 ? 152.450 177.543 143.065 1.00 36.99  ? 677 TRP C N   1 
ATOM   14356 C CA  . TRP C 1 677 ? 153.351 178.607 143.505 1.00 36.20  ? 677 TRP C CA  1 
ATOM   14357 C C   . TRP C 1 677 ? 154.532 178.868 142.555 1.00 41.49  ? 677 TRP C C   1 
ATOM   14358 O O   . TRP C 1 677 ? 155.212 179.881 142.708 1.00 45.96  ? 677 TRP C O   1 
ATOM   14359 C CB  . TRP C 1 677 ? 153.869 178.205 144.892 1.00 38.41  ? 677 TRP C CB  1 
ATOM   14360 C CG  . TRP C 1 677 ? 154.629 176.918 144.921 1.00 36.04  ? 677 TRP C CG  1 
ATOM   14361 C CD1 . TRP C 1 677 ? 154.085 175.697 145.108 1.00 29.48  ? 677 TRP C CD1 1 
ATOM   14362 C CD2 . TRP C 1 677 ? 156.055 176.685 144.715 1.00 37.91  ? 677 TRP C CD2 1 
ATOM   14363 N NE1 . TRP C 1 677 ? 155.063 174.735 145.014 1.00 29.14  ? 677 TRP C NE1 1 
ATOM   14364 C CE2 . TRP C 1 677 ? 156.291 175.281 144.735 1.00 35.67  ? 677 TRP C CE2 1 
ATOM   14365 C CE3 . TRP C 1 677 ? 157.174 177.518 144.502 1.00 37.55  ? 677 TRP C CE3 1 
ATOM   14366 C CZ2 . TRP C 1 677 ? 157.560 174.727 144.529 1.00 37.12  ? 677 TRP C CZ2 1 
ATOM   14367 C CZ3 . TRP C 1 677 ? 158.456 176.972 144.314 1.00 40.16  ? 677 TRP C CZ3 1 
ATOM   14368 C CH2 . TRP C 1 677 ? 158.651 175.580 144.322 1.00 39.88  ? 677 TRP C CH2 1 
ATOM   14369 N N   . CYS C 1 678 ? 154.816 177.973 141.600 1.00 46.18  ? 678 CYS C N   1 
ATOM   14370 C CA  . CYS C 1 678 ? 156.042 177.997 140.792 1.00 45.03  ? 678 CYS C CA  1 
ATOM   14371 C C   . CYS C 1 678 ? 155.798 178.314 139.306 1.00 50.06  ? 678 CYS C C   1 
ATOM   14372 O O   . CYS C 1 678 ? 156.577 179.051 138.703 1.00 54.39  ? 678 CYS C O   1 
ATOM   14373 C CB  . CYS C 1 678 ? 156.778 176.666 140.984 1.00 48.15  ? 678 CYS C CB  1 
ATOM   14374 S SG  . CYS C 1 678 ? 158.471 176.790 140.344 1.00 62.86  ? 678 CYS C SG  1 
ATOM   14375 N N   . ARG C 1 679 ? 154.612 177.896 138.799 1.00 53.64  ? 679 ARG C N   1 
ATOM   14376 C CA  . ARG C 1 679 ? 154.126 178.313 137.447 1.00 55.54  ? 679 ARG C CA  1 
ATOM   14377 C C   . ARG C 1 679 ? 155.301 178.323 136.460 1.00 52.92  ? 679 ARG C C   1 
ATOM   14378 O O   . ARG C 1 679 ? 155.760 179.429 136.115 1.00 54.57  ? 679 ARG C O   1 
ATOM   14379 C CB  . ARG C 1 679 ? 153.493 179.696 137.730 1.00 57.64  ? 679 ARG C CB  1 
ATOM   14380 C CG  . ARG C 1 679 ? 152.217 179.979 136.931 1.00 56.69  ? 679 ARG C CG  1 
ATOM   14381 C CD  . ARG C 1 679 ? 151.012 179.175 137.434 1.00 55.39  ? 679 ARG C CD  1 
ATOM   14382 N NE  . ARG C 1 679 ? 150.676 179.424 138.829 1.00 55.28  ? 679 ARG C NE  1 
ATOM   14383 C CZ  . ARG C 1 679 ? 149.751 180.284 139.236 1.00 59.48  ? 679 ARG C CZ  1 
ATOM   14384 N NH1 . ARG C 1 679 ? 149.513 180.441 140.527 1.00 58.47  ? 679 ARG C NH1 1 
ATOM   14385 N NH2 . ARG C 1 679 ? 149.062 180.983 138.352 1.00 56.61  ? 679 ARG C NH2 1 
ATOM   14386 N N   . ARG C 1 680 ? 155.762 177.149 136.016 1.00 53.43  ? 680 ARG C N   1 
ATOM   14387 C CA  . ARG C 1 680 ? 156.920 176.997 135.108 1.00 53.71  ? 680 ARG C CA  1 
ATOM   14388 C C   . ARG C 1 680 ? 156.647 177.320 133.627 1.00 54.05  ? 680 ARG C C   1 
ATOM   14389 O O   . ARG C 1 680 ? 155.556 177.086 133.111 1.00 53.98  ? 680 ARG C O   1 
ATOM   14390 C CB  . ARG C 1 680 ? 157.572 175.609 135.276 1.00 52.08  ? 680 ARG C CB  1 
ATOM   14391 C CG  . ARG C 1 680 ? 156.944 174.497 134.428 1.00 48.15  ? 680 ARG C CG  1 
ATOM   14392 C CD  . ARG C 1 680 ? 157.638 173.154 134.641 1.00 48.73  ? 680 ARG C CD  1 
ATOM   14393 N NE  . ARG C 1 680 ? 157.382 172.251 133.508 1.00 57.88  ? 680 ARG C NE  1 
ATOM   14394 C CZ  . ARG C 1 680 ? 158.134 171.237 133.118 1.00 54.36  ? 680 ARG C CZ  1 
ATOM   14395 N NH1 . ARG C 1 680 ? 157.910 170.645 131.985 1.00 49.68  ? 680 ARG C NH1 1 
ATOM   14396 N NH2 . ARG C 1 680 ? 159.129 170.801 133.828 1.00 50.11  ? 680 ARG C NH2 1 
ATOM   14397 N N   . LYS C 1 681 ? 157.683 177.789 132.924 1.00 60.46  ? 681 LYS C N   1 
ATOM   14398 C CA  . LYS C 1 681 ? 157.708 178.001 131.463 1.00 62.30  ? 681 LYS C CA  1 
ATOM   14399 C C   . LYS C 1 681 ? 157.838 176.667 130.709 1.00 61.38  ? 681 LYS C C   1 
ATOM   14400 O O   . LYS C 1 681 ? 158.621 175.806 131.105 1.00 56.75  ? 681 LYS C O   1 
ATOM   14401 C CB  . LYS C 1 681 ? 158.871 178.956 131.129 1.00 62.13  ? 681 LYS C CB  1 
ATOM   14402 C CG  . LYS C 1 681 ? 158.886 179.515 129.697 1.00 63.11  ? 681 LYS C CG  1 
ATOM   14403 C CD  . LYS C 1 681 ? 157.737 180.498 129.429 1.00 64.18  ? 681 LYS C CD  1 
ATOM   14404 C CE  . LYS C 1 681 ? 157.913 181.140 128.050 1.00 64.25  ? 681 LYS C CE  1 
ATOM   14405 N NZ  . LYS C 1 681 ? 156.871 182.156 127.777 1.00 63.38  ? 681 LYS C NZ  1 
ATOM   14406 N N   . LYS C 1 682 ? 157.080 176.497 129.621 1.00 55.28  ? 682 LYS C N   1 
ATOM   14407 C CA  . LYS C 1 682 ? 157.084 175.298 128.760 1.00 56.31  ? 682 LYS C CA  1 
ATOM   14408 C C   . LYS C 1 682 ? 158.088 175.410 127.608 1.00 56.33  ? 682 LYS C C   1 
ATOM   14409 O O   . LYS C 1 682 ? 158.472 176.509 127.215 1.00 58.56  ? 682 LYS C O   1 
ATOM   14410 C CB  . LYS C 1 682 ? 155.659 175.040 128.236 1.00 53.05  ? 682 LYS C CB  1 
ATOM   14411 C CG  . LYS C 1 682 ? 154.679 174.791 129.388 1.00 51.98  ? 682 LYS C CG  1 
ATOM   14412 C CD  . LYS C 1 682 ? 153.284 174.429 128.890 1.00 52.69  ? 682 LYS C CD  1 
ATOM   14413 C CE  . LYS C 1 682 ? 152.363 174.256 130.095 1.00 53.91  ? 682 LYS C CE  1 
ATOM   14414 N NZ  . LYS C 1 682 ? 150.959 174.028 129.699 1.00 55.29  ? 682 LYS C NZ  1 
ATOM   14415 N N   . HIS C 1 683 ? 158.471 174.281 127.013 1.00 49.53  ? 683 HIS C N   1 
ATOM   14416 C CA  . HIS C 1 683 ? 159.314 174.219 125.812 1.00 51.95  ? 683 HIS C CA  1 
ATOM   14417 C C   . HIS C 1 683 ? 158.594 173.499 124.661 1.00 53.17  ? 683 HIS C C   1 
ATOM   14418 O O   . HIS C 1 683 ? 157.784 172.597 124.948 1.00 53.04  ? 683 HIS C O   1 
ATOM   14419 C CB  . HIS C 1 683 ? 160.636 173.510 126.132 1.00 55.29  ? 683 HIS C CB  1 
ATOM   14420 C CG  . HIS C 1 683 ? 160.511 172.024 126.202 1.00 55.70  ? 683 HIS C CG  1 
ATOM   14421 N ND1 . HIS C 1 683 ? 160.173 171.366 127.368 1.00 55.07  ? 683 HIS C ND1 1 
ATOM   14422 C CD2 . HIS C 1 683 ? 160.668 171.070 125.259 1.00 52.58  ? 683 HIS C CD2 1 
ATOM   14423 C CE1 . HIS C 1 683 ? 160.132 170.068 127.141 1.00 55.80  ? 683 HIS C CE1 1 
ATOM   14424 N NE2 . HIS C 1 683 ? 160.433 169.861 125.854 1.00 53.51  ? 683 HIS C NE2 1 
ATOM   14425 N N   . ARG C 1 684 ? 158.882 173.888 123.413 1.00 45.86  ? 684 ARG C N   1 
ATOM   14426 C CA  . ARG C 1 684 ? 158.360 173.204 122.222 1.00 38.72  ? 684 ARG C CA  1 
ATOM   14427 C C   . ARG C 1 684 ? 159.021 171.847 122.028 1.00 42.71  ? 684 ARG C C   1 
ATOM   14428 O O   . ARG C 1 684 ? 160.226 171.710 122.234 1.00 42.33  ? 684 ARG C O   1 
ATOM   14429 C CB  . ARG C 1 684 ? 158.571 174.037 120.953 1.00 41.19  ? 684 ARG C CB  1 
ATOM   14430 C CG  . ARG C 1 684 ? 157.811 175.355 121.016 1.00 42.45  ? 684 ARG C CG  1 
ATOM   14431 C CD  . ARG C 1 684 ? 157.668 176.025 119.655 1.00 39.06  ? 684 ARG C CD  1 
ATOM   14432 N NE  . ARG C 1 684 ? 156.642 175.352 118.842 1.00 35.80  ? 684 ARG C NE  1 
ATOM   14433 C CZ  . ARG C 1 684 ? 155.802 175.923 118.004 1.00 42.11  ? 684 ARG C CZ  1 
ATOM   14434 N NH1 . ARG C 1 684 ? 154.855 175.226 117.453 1.00 44.63  ? 684 ARG C NH1 1 
ATOM   14435 N NH2 . ARG C 1 684 ? 155.867 177.185 117.704 1.00 42.48  ? 684 ARG C NH2 1 
ATOM   14436 N N   . GLU C 1 685 ? 158.261 170.882 121.535 1.00 42.30  ? 685 GLU C N   1 
ATOM   14437 C CA  . GLU C 1 685 ? 158.785 169.588 121.112 1.00 38.72  ? 685 GLU C CA  1 
ATOM   14438 C C   . GLU C 1 685 ? 158.759 169.391 119.596 1.00 45.53  ? 685 GLU C C   1 
ATOM   14439 O O   . GLU C 1 685 ? 158.167 170.167 118.846 1.00 50.64  ? 685 GLU C O   1 
ATOM   14440 C CB  . GLU C 1 685 ? 158.104 168.469 121.900 1.00 39.49  ? 685 GLU C CB  1 
ATOM   14441 C CG  . GLU C 1 685 ? 158.627 168.566 123.338 1.00 46.41  ? 685 GLU C CG  1 
ATOM   14442 C CD  . GLU C 1 685 ? 157.966 167.561 124.262 1.00 45.56  ? 685 GLU C CD  1 
ATOM   14443 O OE1 . GLU C 1 685 ? 158.024 166.353 123.956 1.00 44.43  ? 685 GLU C OE1 1 
ATOM   14444 O OE2 . GLU C 1 685 ? 157.421 168.001 125.298 1.00 51.88  ? 685 GLU C OE2 1 
ATOM   14445 N N   . GLY C 1 686 ? 159.495 168.383 119.130 1.00 39.36  ? 686 GLY C N   1 
ATOM   14446 C CA  . GLY C 1 686 ? 159.945 168.329 117.746 1.00 37.17  ? 686 GLY C CA  1 
ATOM   14447 C C   . GLY C 1 686 ? 160.988 169.402 117.432 1.00 37.92  ? 686 GLY C C   1 
ATOM   14448 O O   . GLY C 1 686 ? 161.581 170.006 118.328 1.00 42.37  ? 686 GLY C O   1 
ATOM   14449 N N   . ARG C 1 687 ? 161.234 169.631 116.148 1.00 45.69  ? 687 ARG C N   1 
ATOM   14450 C CA  . ARG C 1 687 ? 162.167 170.630 115.615 1.00 45.41  ? 687 ARG C CA  1 
ATOM   14451 C C   . ARG C 1 687 ? 161.490 171.428 114.519 1.00 44.80  ? 687 ARG C C   1 
ATOM   14452 O O   . ARG C 1 687 ? 160.685 170.879 113.772 1.00 49.27  ? 687 ARG C O   1 
ATOM   14453 C CB  . ARG C 1 687 ? 163.425 169.952 115.058 1.00 47.02  ? 687 ARG C CB  1 
ATOM   14454 C CG  . ARG C 1 687 ? 164.307 169.329 116.144 1.00 48.17  ? 687 ARG C CG  1 
ATOM   14455 C CD  . ARG C 1 687 ? 165.583 168.717 115.556 1.00 52.84  ? 687 ARG C CD  1 
ATOM   14456 N NE  . ARG C 1 687 ? 166.451 169.735 114.931 1.00 56.40  ? 687 ARG C NE  1 
ATOM   14457 C CZ  . ARG C 1 687 ? 167.639 169.545 114.394 1.00 54.61  ? 687 ARG C CZ  1 
ATOM   14458 N NH1 . ARG C 1 687 ? 168.265 170.527 113.819 1.00 54.95  ? 687 ARG C NH1 1 
ATOM   14459 N NH2 . ARG C 1 687 ? 168.233 168.387 114.412 1.00 52.05  ? 687 ARG C NH2 1 
ATOM   14460 N N   . LEU C 1 688 ? 161.837 172.701 114.377 1.00 41.32  ? 688 LEU C N   1 
ATOM   14461 C CA  . LEU C 1 688 ? 161.466 173.483 113.199 1.00 41.24  ? 688 LEU C CA  1 
ATOM   14462 C C   . LEU C 1 688 ? 162.240 172.971 111.975 1.00 42.89  ? 688 LEU C C   1 
ATOM   14463 O O   . LEU C 1 688 ? 163.458 173.115 111.908 1.00 49.03  ? 688 LEU C O   1 
ATOM   14464 C CB  . LEU C 1 688 ? 161.727 174.967 113.489 1.00 45.49  ? 688 LEU C CB  1 
ATOM   14465 C CG  . LEU C 1 688 ? 161.345 175.918 112.349 1.00 42.36  ? 688 LEU C CG  1 
ATOM   14466 C CD1 . LEU C 1 688 ? 159.873 175.788 111.964 1.00 43.14  ? 688 LEU C CD1 1 
ATOM   14467 C CD2 . LEU C 1 688 ? 161.593 177.353 112.798 1.00 46.61  ? 688 LEU C CD2 1 
ATOM   14468 N N   . LEU C 1 689 ? 161.543 172.351 111.023 1.00 44.88  ? 689 LEU C N   1 
ATOM   14469 C CA  . LEU C 1 689 ? 162.113 171.708 109.835 1.00 47.47  ? 689 LEU C CA  1 
ATOM   14470 C C   . LEU C 1 689 ? 161.365 172.136 108.571 1.00 50.99  ? 689 LEU C C   1 
ATOM   14471 O O   . LEU C 1 689 ? 160.143 172.286 108.587 1.00 53.69  ? 689 LEU C O   1 
ATOM   14472 C CB  . LEU C 1 689 ? 162.063 170.173 109.979 1.00 46.69  ? 689 LEU C CB  1 
ATOM   14473 C CG  . LEU C 1 689 ? 162.885 169.590 111.139 1.00 52.28  ? 689 LEU C CG  1 
ATOM   14474 C CD1 . LEU C 1 689 ? 162.607 168.098 111.261 1.00 50.58  ? 689 LEU C CD1 1 
ATOM   14475 C CD2 . LEU C 1 689 ? 164.389 169.770 110.946 1.00 51.59  ? 689 LEU C CD2 1 
ATOM   14476 N N   . LYS C 1 690 ? 162.086 172.294 107.457 1.00 59.06  ? 690 LYS C N   1 
ATOM   14477 C CA  . LYS C 1 690 ? 161.491 172.458 106.125 1.00 60.16  ? 690 LYS C CA  1 
ATOM   14478 C C   . LYS C 1 690 ? 160.980 171.113 105.603 1.00 58.89  ? 690 LYS C C   1 
ATOM   14479 O O   . LYS C 1 690 ? 161.729 170.140 105.577 1.00 57.43  ? 690 LYS C O   1 
ATOM   14480 C CB  . LYS C 1 690 ? 162.512 173.094 105.168 1.00 60.92  ? 690 LYS C CB  1 
ATOM   14481 C CG  . LYS C 1 690 ? 161.877 173.453 103.816 1.00 61.74  ? 690 LYS C CG  1 
ATOM   14482 C CD  . LYS C 1 690 ? 162.918 174.035 102.857 1.00 61.97  ? 690 LYS C CD  1 
ATOM   14483 C CE  . LYS C 1 690 ? 162.314 174.212 101.466 1.00 63.99  ? 690 LYS C CE  1 
ATOM   14484 N NZ  . LYS C 1 690 ? 163.325 174.666 100.487 1.00 62.31  ? 690 LYS C NZ  1 
ATOM   14485 N N   . VAL C 1 691 ? 159.727 171.069 105.154 1.00 55.27  ? 691 VAL C N   1 
ATOM   14486 C CA  . VAL C 1 691 ? 159.074 169.863 104.608 1.00 57.78  ? 691 VAL C CA  1 
ATOM   14487 C C   . VAL C 1 691 ? 158.698 169.986 103.122 1.00 56.02  ? 691 VAL C C   1 
ATOM   14488 O O   . VAL C 1 691 ? 158.380 168.983 102.486 1.00 53.82  ? 691 VAL C O   1 
ATOM   14489 C CB  . VAL C 1 691 ? 157.866 169.438 105.471 1.00 52.48  ? 691 VAL C CB  1 
ATOM   14490 C CG1 . VAL C 1 691 ? 158.286 169.078 106.899 1.00 46.28  ? 691 VAL C CG1 1 
ATOM   14491 C CG2 . VAL C 1 691 ? 156.773 170.503 105.552 1.00 50.63  ? 691 VAL C CG2 1 
ATOM   14492 N N   . GLY C 1 692 ? 158.777 171.184 102.537 1.00 63.77  ? 692 GLY C N   1 
ATOM   14493 C CA  . GLY C 1 692 ? 158.477 171.437 101.124 1.00 64.55  ? 692 GLY C CA  1 
ATOM   14494 C C   . GLY C 1 692 ? 158.378 172.929 100.806 1.00 69.59  ? 692 GLY C C   1 
ATOM   14495 O O   . GLY C 1 692 ? 159.066 173.741 101.426 1.00 69.93  ? 692 GLY C O   1 
ATOM   14496 N N   . THR C 1 693 ? 157.490 173.306 99.879  1.00 75.77  ? 693 THR C N   1 
ATOM   14497 C CA  . THR C 1 693 ? 157.114 174.703 99.572  1.00 75.33  ? 693 THR C CA  1 
ATOM   14498 C C   . THR C 1 693 ? 155.596 174.884 99.706  1.00 74.67  ? 693 THR C C   1 
ATOM   14499 O O   . THR C 1 693 ? 154.839 173.991 99.322  1.00 75.02  ? 693 THR C O   1 
ATOM   14500 C CB  . THR C 1 693 ? 157.600 175.111 98.171  1.00 76.07  ? 693 THR C CB  1 
ATOM   14501 O OG1 . THR C 1 693 ? 159.002 174.969 98.085  1.00 75.68  ? 693 THR C OG1 1 
ATOM   14502 C CG2 . THR C 1 693 ? 157.287 176.567 97.830  1.00 75.35  ? 693 THR C CG2 1 
ATOM   14503 N N   . ARG C 1 694 ? 155.134 176.006 100.276 1.00 77.02  ? 694 ARG C N   1 
ATOM   14504 C CA  . ARG C 1 694 ? 153.719 176.208 100.648 1.00 78.69  ? 694 ARG C CA  1 
ATOM   14505 C C   . ARG C 1 694 ? 152.788 176.305 99.432  1.00 80.35  ? 694 ARG C C   1 
ATOM   14506 O O   . ARG C 1 694 ? 153.182 176.778 98.365  1.00 78.44  ? 694 ARG C O   1 
ATOM   14507 C CB  . ARG C 1 694 ? 153.557 177.452 101.541 1.00 77.78  ? 694 ARG C CB  1 
ATOM   14508 C CG  . ARG C 1 694 ? 154.365 177.354 102.842 1.00 77.72  ? 694 ARG C CG  1 
ATOM   14509 C CD  . ARG C 1 694 ? 154.103 178.539 103.777 1.00 78.66  ? 694 ARG C CD  1 
ATOM   14510 N NE  . ARG C 1 694 ? 152.772 178.462 104.407 1.00 81.21  ? 694 ARG C NE  1 
ATOM   14511 C CZ  . ARG C 1 694 ? 152.214 179.376 105.178 1.00 81.40  ? 694 ARG C CZ  1 
ATOM   14512 N NH1 . ARG C 1 694 ? 151.041 179.167 105.697 1.00 78.98  ? 694 ARG C NH1 1 
ATOM   14513 N NH2 . ARG C 1 694 ? 152.794 180.508 105.449 1.00 78.90  ? 694 ARG C NH2 1 
ATOM   14514 N N   . GLY C 1 695 ? 151.533 175.899 99.611  1.00 78.83  ? 695 GLY C N   1 
ATOM   14515 C CA  . GLY C 1 695 ? 150.504 175.954 98.571  1.00 78.52  ? 695 GLY C CA  1 
ATOM   14516 C C   . GLY C 1 695 ? 149.191 175.290 98.981  1.00 78.43  ? 695 GLY C C   1 
ATOM   14517 O O   . GLY C 1 695 ? 149.152 174.459 99.894  1.00 77.61  ? 695 GLY C O   1 
ATOM   14518 N N   . PRO C 1 699 ? 159.199 178.733 101.476 1.00 77.00  ? 699 PRO C N   1 
ATOM   14519 C CA  . PRO C 1 699 ? 159.399 177.415 102.060 1.00 78.11  ? 699 PRO C CA  1 
ATOM   14520 C C   . PRO C 1 699 ? 158.314 177.057 103.086 1.00 77.42  ? 699 PRO C C   1 
ATOM   14521 O O   . PRO C 1 699 ? 157.793 177.914 103.801 1.00 74.98  ? 699 PRO C O   1 
ATOM   14522 C CB  . PRO C 1 699 ? 160.787 177.468 102.699 1.00 76.40  ? 699 PRO C CB  1 
ATOM   14523 C CG  . PRO C 1 699 ? 160.940 178.938 103.074 1.00 75.94  ? 699 PRO C CG  1 
ATOM   14524 C CD  . PRO C 1 699 ? 160.217 179.653 101.939 1.00 76.68  ? 699 PRO C CD  1 
ATOM   14525 N N   . ASP C 1 700 ? 157.981 175.769 103.170 1.00 67.57  ? 700 ASP C N   1 
ATOM   14526 C CA  . ASP C 1 700 ? 157.064 175.210 104.169 1.00 67.15  ? 700 ASP C CA  1 
ATOM   14527 C C   . ASP C 1 700 ? 157.868 174.685 105.364 1.00 66.10  ? 700 ASP C C   1 
ATOM   14528 O O   . ASP C 1 700 ? 158.435 173.593 105.307 1.00 64.84  ? 700 ASP C O   1 
ATOM   14529 C CB  . ASP C 1 700 ? 156.208 174.119 103.503 1.00 66.65  ? 700 ASP C CB  1 
ATOM   14530 C CG  . ASP C 1 700 ? 155.077 173.574 104.379 1.00 69.39  ? 700 ASP C CG  1 
ATOM   14531 O OD1 . ASP C 1 700 ? 154.893 174.021 105.529 1.00 66.68  ? 700 ASP C OD1 1 
ATOM   14532 O OD2 . ASP C 1 700 ? 154.329 172.699 103.896 1.00 67.74  ? 700 ASP C OD2 1 
ATOM   14533 N N   . GLU C 1 701 ? 157.983 175.491 106.420 1.00 61.62  ? 701 GLU C N   1 
ATOM   14534 C CA  . GLU C 1 701 ? 158.694 175.144 107.653 1.00 61.01  ? 701 GLU C CA  1 
ATOM   14535 C C   . GLU C 1 701 ? 157.717 174.916 108.805 1.00 59.21  ? 701 GLU C C   1 
ATOM   14536 O O   . GLU C 1 701 ? 156.859 175.759 109.073 1.00 61.25  ? 701 GLU C O   1 
ATOM   14537 C CB  . GLU C 1 701 ? 159.716 176.226 108.028 1.00 62.17  ? 701 GLU C CB  1 
ATOM   14538 C CG  . GLU C 1 701 ? 160.862 176.332 107.018 1.00 62.52  ? 701 GLU C CG  1 
ATOM   14539 C CD  . GLU C 1 701 ? 161.994 177.229 107.537 1.00 64.57  ? 701 GLU C CD  1 
ATOM   14540 O OE1 . GLU C 1 701 ? 161.725 178.375 107.954 1.00 63.18  ? 701 GLU C OE1 1 
ATOM   14541 O OE2 . GLU C 1 701 ? 163.165 176.799 107.516 1.00 62.51  ? 701 GLU C OE2 1 
ATOM   14542 N N   . ARG C 1 702 ? 157.854 173.790 109.507 1.00 48.02  ? 702 ARG C N   1 
ATOM   14543 C CA  . ARG C 1 702 ? 156.938 173.362 110.574 1.00 39.04  ? 702 ARG C CA  1 
ATOM   14544 C C   . ARG C 1 702 ? 157.670 172.751 111.747 1.00 38.77  ? 702 ARG C C   1 
ATOM   14545 O O   . ARG C 1 702 ? 158.730 172.164 111.581 1.00 44.04  ? 702 ARG C O   1 
ATOM   14546 C CB  . ARG C 1 702 ? 155.950 172.318 110.047 1.00 40.84  ? 702 ARG C CB  1 
ATOM   14547 C CG  . ARG C 1 702 ? 155.241 172.753 108.772 1.00 43.13  ? 702 ARG C CG  1 
ATOM   14548 C CD  . ARG C 1 702 ? 154.081 171.815 108.519 1.00 40.16  ? 702 ARG C CD  1 
ATOM   14549 N NE  . ARG C 1 702 ? 153.578 171.983 107.163 1.00 41.94  ? 702 ARG C NE  1 
ATOM   14550 C CZ  . ARG C 1 702 ? 152.617 171.277 106.621 1.00 40.72  ? 702 ARG C CZ  1 
ATOM   14551 N NH1 . ARG C 1 702 ? 152.452 171.329 105.343 1.00 39.35  ? 702 ARG C NH1 1 
ATOM   14552 N NH2 . ARG C 1 702 ? 151.839 170.501 107.320 1.00 41.77  ? 702 ARG C NH2 1 
ATOM   14553 N N   . TRP C 1 703 ? 157.070 172.840 112.925 1.00 41.81  ? 703 TRP C N   1 
ATOM   14554 C CA  . TRP C 1 703 ? 157.490 172.067 114.087 1.00 38.11  ? 703 TRP C CA  1 
ATOM   14555 C C   . TRP C 1 703 ? 157.050 170.618 113.917 1.00 35.52  ? 703 TRP C C   1 
ATOM   14556 O O   . TRP C 1 703 ? 155.869 170.284 113.977 1.00 34.30  ? 703 TRP C O   1 
ATOM   14557 C CB  . TRP C 1 703 ? 156.972 172.719 115.360 1.00 37.41  ? 703 TRP C CB  1 
ATOM   14558 C CG  . TRP C 1 703 ? 157.751 173.948 115.689 1.00 37.16  ? 703 TRP C CG  1 
ATOM   14559 C CD1 . TRP C 1 703 ? 157.551 175.179 115.166 1.00 38.88  ? 703 TRP C CD1 1 
ATOM   14560 C CD2 . TRP C 1 703 ? 158.935 174.063 116.527 1.00 39.16  ? 703 TRP C CD2 1 
ATOM   14561 N NE1 . TRP C 1 703 ? 158.518 176.043 115.630 1.00 40.56  ? 703 TRP C NE1 1 
ATOM   14562 C CE2 . TRP C 1 703 ? 159.401 175.409 116.471 1.00 38.91  ? 703 TRP C CE2 1 
ATOM   14563 C CE3 . TRP C 1 703 ? 159.655 173.169 117.348 1.00 37.66  ? 703 TRP C CE3 1 
ATOM   14564 C CZ2 . TRP C 1 703 ? 160.523 175.846 117.185 1.00 35.37  ? 703 TRP C CZ2 1 
ATOM   14565 C CZ3 . TRP C 1 703 ? 160.776 173.599 118.079 1.00 38.85  ? 703 TRP C CZ3 1 
ATOM   14566 C CH2 . TRP C 1 703 ? 161.210 174.934 117.998 1.00 40.49  ? 703 TRP C CH2 1 
ATOM   14567 N N   . CYS C 1 704 ? 158.032 169.771 113.652 1.00 39.05  ? 704 CYS C N   1 
ATOM   14568 C CA  . CYS C 1 704 ? 157.850 168.391 113.249 1.00 32.65  ? 704 CYS C CA  1 
ATOM   14569 C C   . CYS C 1 704 ? 158.535 167.457 114.235 1.00 30.99  ? 704 CYS C C   1 
ATOM   14570 O O   . CYS C 1 704 ? 159.626 167.731 114.726 1.00 42.15  ? 704 CYS C O   1 
ATOM   14571 C CB  . CYS C 1 704 ? 158.393 168.206 111.828 1.00 33.76  ? 704 CYS C CB  1 
ATOM   14572 S SG  . CYS C 1 704 ? 157.081 168.538 110.630 1.00 52.07  ? 704 CYS C SG  1 
ATOM   14573 N N   . PHE C 1 705 ? 157.905 166.328 114.498 1.00 23.79  ? 705 PHE C N   1 
ATOM   14574 C CA  . PHE C 1 705 ? 158.370 165.325 115.438 1.00 22.82  ? 705 PHE C CA  1 
ATOM   14575 C C   . PHE C 1 705 ? 158.682 164.014 114.728 1.00 23.91  ? 705 PHE C C   1 
ATOM   14576 O O   . PHE C 1 705 ? 157.821 163.446 114.058 1.00 26.27  ? 705 PHE C O   1 
ATOM   14577 C CB  . PHE C 1 705 ? 157.288 165.205 116.496 1.00 26.86  ? 705 PHE C CB  1 
ATOM   14578 C CG  . PHE C 1 705 ? 157.558 164.243 117.624 1.00 27.04  ? 705 PHE C CG  1 
ATOM   14579 C CD1 . PHE C 1 705 ? 158.396 164.621 118.683 1.00 27.43  ? 705 PHE C CD1 1 
ATOM   14580 C CD2 . PHE C 1 705 ? 156.907 163.003 117.645 1.00 25.57  ? 705 PHE C CD2 1 
ATOM   14581 C CE1 . PHE C 1 705 ? 158.599 163.745 119.761 1.00 27.12  ? 705 PHE C CE1 1 
ATOM   14582 C CE2 . PHE C 1 705 ? 157.110 162.132 118.719 1.00 28.26  ? 705 PHE C CE2 1 
ATOM   14583 C CZ  . PHE C 1 705 ? 157.961 162.497 119.772 1.00 24.70  ? 705 PHE C CZ  1 
ATOM   14584 N N   . ARG C 1 706 ? 159.925 163.550 114.852 1.00 30.98  ? 706 ARG C N   1 
ATOM   14585 C CA  . ARG C 1 706 ? 160.423 162.327 114.230 1.00 25.36  ? 706 ARG C CA  1 
ATOM   14586 C C   . ARG C 1 706 ? 159.966 161.089 114.988 1.00 23.96  ? 706 ARG C C   1 
ATOM   14587 O O   . ARG C 1 706 ? 160.284 160.918 116.161 1.00 32.09  ? 706 ARG C O   1 
ATOM   14588 C CB  . ARG C 1 706 ? 161.948 162.431 114.119 1.00 30.40  ? 706 ARG C CB  1 
ATOM   14589 C CG  . ARG C 1 706 ? 162.564 161.266 113.346 1.00 31.63  ? 706 ARG C CG  1 
ATOM   14590 C CD  . ARG C 1 706 ? 164.066 161.463 113.149 1.00 34.00  ? 706 ARG C CD  1 
ATOM   14591 N NE  . ARG C 1 706 ? 164.346 162.518 112.165 1.00 35.80  ? 706 ARG C NE  1 
ATOM   14592 C CZ  . ARG C 1 706 ? 164.856 163.716 112.346 1.00 39.58  ? 706 ARG C CZ  1 
ATOM   14593 N NH1 . ARG C 1 706 ? 165.016 164.512 111.338 1.00 32.26  ? 706 ARG C NH1 1 
ATOM   14594 N NH2 . ARG C 1 706 ? 165.207 164.149 113.518 1.00 39.62  ? 706 ARG C NH2 1 
ATOM   14595 N N   . VAL C 1 707 ? 159.267 160.202 114.299 1.00 29.09  ? 707 VAL C N   1 
ATOM   14596 C CA  . VAL C 1 707 ? 158.825 158.896 114.792 1.00 27.48  ? 707 VAL C CA  1 
ATOM   14597 C C   . VAL C 1 707 ? 159.423 157.812 113.900 1.00 32.06  ? 707 VAL C C   1 
ATOM   14598 O O   . VAL C 1 707 ? 159.404 157.919 112.678 1.00 36.12  ? 707 VAL C O   1 
ATOM   14599 C CB  . VAL C 1 707 ? 157.291 158.807 114.846 1.00 32.19  ? 707 VAL C CB  1 
ATOM   14600 C CG1 . VAL C 1 707 ? 156.811 157.472 115.416 1.00 25.98  ? 707 VAL C CG1 1 
ATOM   14601 C CG2 . VAL C 1 707 ? 156.663 159.914 115.696 1.00 32.26  ? 707 VAL C CG2 1 
ATOM   14602 N N   . GLU C 1 708 ? 159.968 156.768 114.508 1.00 40.98  ? 708 GLU C N   1 
ATOM   14603 C CA  . GLU C 1 708 ? 160.524 155.619 113.805 1.00 31.70  ? 708 GLU C CA  1 
ATOM   14604 C C   . GLU C 1 708 ? 159.608 154.426 114.073 1.00 36.03  ? 708 GLU C C   1 
ATOM   14605 O O   . GLU C 1 708 ? 159.469 153.980 115.209 1.00 45.02  ? 708 GLU C O   1 
ATOM   14606 C CB  . GLU C 1 708 ? 161.961 155.345 114.284 1.00 35.70  ? 708 GLU C CB  1 
ATOM   14607 C CG  . GLU C 1 708 ? 162.869 156.585 114.299 1.00 37.57  ? 708 GLU C CG  1 
ATOM   14608 C CD  . GLU C 1 708 ? 164.267 156.310 114.871 1.00 46.39  ? 708 GLU C CD  1 
ATOM   14609 O OE1 . GLU C 1 708 ? 164.420 155.402 115.719 1.00 48.97  ? 708 GLU C OE1 1 
ATOM   14610 O OE2 . GLU C 1 708 ? 165.215 157.047 114.516 1.00 47.67  ? 708 GLU C OE2 1 
ATOM   14611 N N   . GLU C 1 709 ? 158.960 153.907 113.040 1.00 41.77  ? 709 GLU C N   1 
ATOM   14612 C CA  . GLU C 1 709 ? 158.110 152.722 113.117 1.00 40.39  ? 709 GLU C CA  1 
ATOM   14613 C C   . GLU C 1 709 ? 158.889 151.544 112.543 1.00 43.47  ? 709 GLU C C   1 
ATOM   14614 O O   . GLU C 1 709 ? 159.388 151.619 111.423 1.00 42.80  ? 709 GLU C O   1 
ATOM   14615 C CB  . GLU C 1 709 ? 156.791 152.954 112.355 1.00 41.51  ? 709 GLU C CB  1 
ATOM   14616 C CG  . GLU C 1 709 ? 155.902 151.697 112.332 1.00 45.40  ? 709 GLU C CG  1 
ATOM   14617 C CD  . GLU C 1 709 ? 154.609 151.821 111.506 1.00 51.18  ? 709 GLU C CD  1 
ATOM   14618 O OE1 . GLU C 1 709 ? 154.455 152.774 110.710 1.00 51.45  ? 709 GLU C OE1 1 
ATOM   14619 O OE2 . GLU C 1 709 ? 153.750 150.914 111.620 1.00 48.74  ? 709 GLU C OE2 1 
ATOM   14620 N N   . VAL C 1 710 ? 158.954 150.434 113.278 1.00 43.86  ? 710 VAL C N   1 
ATOM   14621 C CA  . VAL C 1 710 ? 159.376 149.142 112.739 1.00 40.85  ? 710 VAL C CA  1 
ATOM   14622 C C   . VAL C 1 710 ? 158.153 148.239 112.681 1.00 37.06  ? 710 VAL C C   1 
ATOM   14623 O O   . VAL C 1 710 ? 157.495 148.025 113.696 1.00 42.17  ? 710 VAL C O   1 
ATOM   14624 C CB  . VAL C 1 710 ? 160.506 148.502 113.558 1.00 39.94  ? 710 VAL C CB  1 
ATOM   14625 C CG1 . VAL C 1 710 ? 161.052 147.276 112.824 1.00 39.21  ? 710 VAL C CG1 1 
ATOM   14626 C CG2 . VAL C 1 710 ? 161.651 149.483 113.821 1.00 39.17  ? 710 VAL C CG2 1 
ATOM   14627 N N   . ASN C 1 711 ? 157.818 147.718 111.505 1.00 39.11  ? 711 ASN C N   1 
ATOM   14628 C CA  . ASN C 1 711 ? 156.606 146.928 111.301 1.00 37.09  ? 711 ASN C CA  1 
ATOM   14629 C C   . ASN C 1 711 ? 156.830 145.860 110.222 1.00 40.16  ? 711 ASN C C   1 
ATOM   14630 O O   . ASN C 1 711 ? 156.518 146.053 109.051 1.00 47.70  ? 711 ASN C O   1 
ATOM   14631 C CB  . ASN C 1 711 ? 155.453 147.898 111.000 1.00 40.55  ? 711 ASN C CB  1 
ATOM   14632 C CG  . ASN C 1 711 ? 154.081 147.268 111.131 1.00 43.15  ? 711 ASN C CG  1 
ATOM   14633 O OD1 . ASN C 1 711 ? 153.903 146.062 111.060 1.00 43.03  ? 711 ASN C OD1 1 
ATOM   14634 N ND2 . ASN C 1 711 ? 153.075 148.080 111.340 1.00 45.57  ? 711 ASN C ND2 1 
ATOM   14635 N N   . TRP C 1 712 ? 157.390 144.722 110.627 1.00 37.99  ? 712 TRP C N   1 
ATOM   14636 C CA  . TRP C 1 712 ? 157.662 143.574 109.761 1.00 37.64  ? 712 TRP C CA  1 
ATOM   14637 C C   . TRP C 1 712 ? 156.400 142.986 109.139 1.00 39.17  ? 712 TRP C C   1 
ATOM   14638 O O   . TRP C 1 712 ? 156.385 142.703 107.947 1.00 42.13  ? 712 TRP C O   1 
ATOM   14639 C CB  . TRP C 1 712 ? 158.369 142.492 110.581 1.00 41.29  ? 712 TRP C CB  1 
ATOM   14640 C CG  . TRP C 1 712 ? 159.781 142.779 110.960 1.00 39.45  ? 712 TRP C CG  1 
ATOM   14641 C CD1 . TRP C 1 712 ? 160.192 143.486 112.032 1.00 41.04  ? 712 TRP C CD1 1 
ATOM   14642 C CD2 . TRP C 1 712 ? 160.996 142.330 110.285 1.00 38.26  ? 712 TRP C CD2 1 
ATOM   14643 N NE1 . TRP C 1 712 ? 161.570 143.519 112.065 1.00 42.60  ? 712 TRP C NE1 1 
ATOM   14644 C CE2 . TRP C 1 712 ? 162.115 142.794 111.034 1.00 41.39  ? 712 TRP C CE2 1 
ATOM   14645 C CE3 . TRP C 1 712 ? 161.257 141.533 109.155 1.00 34.27  ? 712 TRP C CE3 1 
ATOM   14646 C CZ2 . TRP C 1 712 ? 163.431 142.477 110.678 1.00 40.61  ? 712 TRP C CZ2 1 
ATOM   14647 C CZ3 . TRP C 1 712 ? 162.577 141.207 108.791 1.00 34.62  ? 712 TRP C CZ3 1 
ATOM   14648 C CH2 . TRP C 1 712 ? 163.658 141.673 109.556 1.00 39.78  ? 712 TRP C CH2 1 
ATOM   14649 N N   . ALA C 1 713 ? 155.331 142.842 109.917 1.00 44.85  ? 713 ALA C N   1 
ATOM   14650 C CA  . ALA C 1 713 ? 154.076 142.271 109.446 1.00 43.61  ? 713 ALA C CA  1 
ATOM   14651 C C   . ALA C 1 713 ? 153.430 143.114 108.335 1.00 45.88  ? 713 ALA C C   1 
ATOM   14652 O O   . ALA C 1 713 ? 152.987 142.565 107.332 1.00 49.51  ? 713 ALA C O   1 
ATOM   14653 C CB  . ALA C 1 713 ? 153.147 142.094 110.650 1.00 43.41  ? 713 ALA C CB  1 
ATOM   14654 N N   . ALA C 1 714 ? 153.414 144.444 108.465 1.00 44.29  ? 714 ALA C N   1 
ATOM   14655 C CA  . ALA C 1 714 ? 152.935 145.323 107.407 1.00 40.89  ? 714 ALA C CA  1 
ATOM   14656 C C   . ALA C 1 714 ? 153.872 145.346 106.192 1.00 44.56  ? 714 ALA C C   1 
ATOM   14657 O O   . ALA C 1 714 ? 153.405 145.380 105.057 1.00 48.15  ? 714 ALA C O   1 
ATOM   14658 C CB  . ALA C 1 714 ? 152.742 146.729 107.974 1.00 42.47  ? 714 ALA C CB  1 
ATOM   14659 N N   . TRP C 1 715 ? 155.187 145.306 106.406 1.00 41.71  ? 715 TRP C N   1 
ATOM   14660 C CA  . TRP C 1 715 ? 156.175 145.343 105.330 1.00 42.93  ? 715 TRP C CA  1 
ATOM   14661 C C   . TRP C 1 715 ? 156.177 144.079 104.472 1.00 42.69  ? 715 TRP C C   1 
ATOM   14662 O O   . TRP C 1 715 ? 156.092 144.180 103.252 1.00 46.29  ? 715 TRP C O   1 
ATOM   14663 C CB  . TRP C 1 715 ? 157.551 145.624 105.926 1.00 38.51  ? 715 TRP C CB  1 
ATOM   14664 C CG  . TRP C 1 715 ? 158.695 145.481 104.979 1.00 38.24  ? 715 TRP C CG  1 
ATOM   14665 C CD1 . TRP C 1 715 ? 158.940 146.270 103.915 1.00 36.87  ? 715 TRP C CD1 1 
ATOM   14666 C CD2 . TRP C 1 715 ? 159.749 144.477 104.983 1.00 41.69  ? 715 TRP C CD2 1 
ATOM   14667 N NE1 . TRP C 1 715 ? 160.086 145.842 103.277 1.00 40.10  ? 715 TRP C NE1 1 
ATOM   14668 C CE2 . TRP C 1 715 ? 160.641 144.752 103.910 1.00 39.79  ? 715 TRP C CE2 1 
ATOM   14669 C CE3 . TRP C 1 715 ? 160.057 143.376 105.807 1.00 34.42  ? 715 TRP C CE3 1 
ATOM   14670 C CZ2 . TRP C 1 715 ? 161.796 143.999 103.675 1.00 38.79  ? 715 TRP C CZ2 1 
ATOM   14671 C CZ3 . TRP C 1 715 ? 161.208 142.610 105.581 1.00 38.19  ? 715 TRP C CZ3 1 
ATOM   14672 C CH2 . TRP C 1 715 ? 162.083 142.922 104.529 1.00 38.69  ? 715 TRP C CH2 1 
ATOM   14673 N N   . GLU C 1 716 ? 156.193 142.886 105.067 1.00 49.29  ? 716 GLU C N   1 
ATOM   14674 C CA  . GLU C 1 716 ? 156.239 141.626 104.315 1.00 51.15  ? 716 GLU C CA  1 
ATOM   14675 C C   . GLU C 1 716 ? 155.040 141.429 103.378 1.00 55.42  ? 716 GLU C C   1 
ATOM   14676 O O   . GLU C 1 716 ? 155.189 140.899 102.280 1.00 58.35  ? 716 GLU C O   1 
ATOM   14677 C CB  . GLU C 1 716 ? 156.346 140.440 105.276 1.00 50.87  ? 716 GLU C CB  1 
ATOM   14678 C CG  . GLU C 1 716 ? 157.758 140.317 105.857 1.00 56.54  ? 716 GLU C CG  1 
ATOM   14679 C CD  . GLU C 1 716 ? 157.987 138.948 106.511 1.00 57.04  ? 716 GLU C CD  1 
ATOM   14680 O OE1 . GLU C 1 716 ? 157.080 138.455 107.213 1.00 55.54  ? 716 GLU C OE1 1 
ATOM   14681 O OE2 . GLU C 1 716 ? 159.067 138.358 106.284 1.00 56.04  ? 716 GLU C OE2 1 
ATOM   14682 N N   . LYS C 1 717 ? 153.862 141.942 103.753 1.00 52.19  ? 717 LYS C N   1 
ATOM   14683 C CA  . LYS C 1 717 ? 152.658 141.938 102.908 1.00 51.99  ? 717 LYS C CA  1 
ATOM   14684 C C   . LYS C 1 717 ? 152.799 142.774 101.632 1.00 54.51  ? 717 LYS C C   1 
ATOM   14685 O O   . LYS C 1 717 ? 152.056 142.540 100.682 1.00 59.27  ? 717 LYS C O   1 
ATOM   14686 C CB  . LYS C 1 717 ? 151.458 142.409 103.740 1.00 52.36  ? 717 LYS C CB  1 
ATOM   14687 C CG  . LYS C 1 717 ? 151.091 141.374 104.814 1.00 55.04  ? 717 LYS C CG  1 
ATOM   14688 C CD  . LYS C 1 717 ? 149.999 141.899 105.750 1.00 56.54  ? 717 LYS C CD  1 
ATOM   14689 C CE  . LYS C 1 717 ? 149.789 140.900 106.891 1.00 56.49  ? 717 LYS C CE  1 
ATOM   14690 N NZ  . LYS C 1 717 ? 148.727 141.343 107.822 1.00 55.74  ? 717 LYS C NZ  1 
ATOM   14691 N N   . THR C 1 718 ? 153.748 143.707 101.569 1.00 49.56  ? 718 THR C N   1 
ATOM   14692 C CA  . THR C 1 718 ? 154.027 144.522 100.369 1.00 50.56  ? 718 THR C CA  1 
ATOM   14693 C C   . THR C 1 718 ? 154.952 143.841 99.355  1.00 52.71  ? 718 THR C C   1 
ATOM   14694 O O   . THR C 1 718 ? 155.043 144.295 98.213  1.00 54.89  ? 718 THR C O   1 
ATOM   14695 C CB  . THR C 1 718 ? 154.614 145.902 100.711 1.00 54.54  ? 718 THR C CB  1 
ATOM   14696 O OG1 . THR C 1 718 ? 155.946 145.829 101.165 1.00 53.65  ? 718 THR C OG1 1 
ATOM   14697 C CG2 . THR C 1 718 ? 153.796 146.648 101.760 1.00 53.69  ? 718 THR C CG2 1 
ATOM   14698 N N   . LEU C 1 719 ? 155.655 142.773 99.733  1.00 49.98  ? 719 LEU C N   1 
ATOM   14699 C CA  . LEU C 1 719 ? 156.689 142.154 98.900  1.00 52.53  ? 719 LEU C CA  1 
ATOM   14700 C C   . LEU C 1 719 ? 156.072 141.319 97.772  1.00 55.35  ? 719 LEU C C   1 
ATOM   14701 O O   . LEU C 1 719 ? 156.645 141.204 96.686  1.00 54.07  ? 719 LEU C O   1 
ATOM   14702 C CB  . LEU C 1 719 ? 157.648 141.321 99.777  1.00 54.46  ? 719 LEU C CB  1 
ATOM   14703 C CG  . LEU C 1 719 ? 158.273 142.080 100.964 1.00 52.49  ? 719 LEU C CG  1 
ATOM   14704 C CD1 . LEU C 1 719 ? 159.241 141.165 101.710 1.00 50.33  ? 719 LEU C CD1 1 
ATOM   14705 C CD2 . LEU C 1 719 ? 159.015 143.340 100.540 1.00 48.63  ? 719 LEU C CD2 1 
ATOM   14706 N N   . ARG D 1 74  ? 185.273 174.645 88.724  1.00 118.61 ? 74  ARG D N   1 
ATOM   14707 C CA  . ARG D 1 74  ? 185.389 173.577 89.755  1.00 119.70 ? 74  ARG D CA  1 
ATOM   14708 C C   . ARG D 1 74  ? 184.128 172.712 89.758  1.00 119.77 ? 74  ARG D C   1 
ATOM   14709 O O   . ARG D 1 74  ? 183.266 172.919 88.878  1.00 119.17 ? 74  ARG D O   1 
ATOM   14710 C CB  . ARG D 1 74  ? 185.600 174.182 91.146  1.00 119.43 ? 74  ARG D CB  1 
ATOM   14711 C CG  . ARG D 1 74  ? 184.332 174.708 91.803  1.00 118.70 ? 74  ARG D CG  1 
ATOM   14712 C CD  . ARG D 1 74  ? 184.638 175.693 92.913  1.00 118.82 ? 74  ARG D CD  1 
ATOM   14713 N NE  . ARG D 1 74  ? 185.658 175.216 93.835  1.00 119.66 ? 74  ARG D NE  1 
ATOM   14714 C CZ  . ARG D 1 74  ? 185.408 174.583 94.975  1.00 119.51 ? 74  ARG D CZ  1 
ATOM   14715 N NH1 . ARG D 1 74  ? 186.408 174.189 95.747  1.00 119.04 ? 74  ARG D NH1 1 
ATOM   14716 N NH2 . ARG D 1 74  ? 184.161 174.347 95.343  1.00 118.94 ? 74  ARG D NH2 1 
ATOM   14717 N N   . PHE D 1 75  ? 184.027 171.796 90.725  1.00 116.99 ? 75  PHE D N   1 
ATOM   14718 C CA  . PHE D 1 75  ? 182.862 170.902 90.828  1.00 116.91 ? 75  PHE D CA  1 
ATOM   14719 C C   . PHE D 1 75  ? 182.710 170.421 92.281  1.00 116.45 ? 75  PHE D C   1 
ATOM   14720 O O   . PHE D 1 75  ? 183.678 169.988 92.899  1.00 115.50 ? 75  PHE D O   1 
ATOM   14721 C CB  . PHE D 1 75  ? 183.000 169.729 89.846  1.00 116.08 ? 75  PHE D CB  1 
ATOM   14722 C CG  . PHE D 1 75  ? 181.677 169.202 89.317  1.00 115.97 ? 75  PHE D CG  1 
ATOM   14723 C CD1 . PHE D 1 75  ? 180.711 168.645 90.176  1.00 115.54 ? 75  PHE D CD1 1 
ATOM   14724 C CD2 . PHE D 1 75  ? 181.418 169.259 87.936  1.00 115.49 ? 75  PHE D CD2 1 
ATOM   14725 C CE1 . PHE D 1 75  ? 179.508 168.139 89.659  1.00 115.90 ? 75  PHE D CE1 1 
ATOM   14726 C CE2 . PHE D 1 75  ? 180.230 168.725 87.417  1.00 115.28 ? 75  PHE D CE2 1 
ATOM   14727 C CZ  . PHE D 1 75  ? 179.271 168.163 88.278  1.00 115.32 ? 75  PHE D CZ  1 
ATOM   14728 N N   . ASP D 1 76  ? 181.510 170.502 92.850  1.00 114.73 ? 76  ASP D N   1 
ATOM   14729 C CA  . ASP D 1 76  ? 181.317 170.442 94.304  1.00 114.26 ? 76  ASP D CA  1 
ATOM   14730 C C   . ASP D 1 76  ? 180.080 169.618 94.705  1.00 115.33 ? 76  ASP D C   1 
ATOM   14731 O O   . ASP D 1 76  ? 179.187 169.373 93.895  1.00 114.72 ? 76  ASP D O   1 
ATOM   14732 C CB  . ASP D 1 76  ? 181.267 171.886 94.836  1.00 113.94 ? 76  ASP D CB  1 
ATOM   14733 C CG  . ASP D 1 76  ? 181.822 172.040 96.255  1.00 115.37 ? 76  ASP D CG  1 
ATOM   14734 O OD1 . ASP D 1 76  ? 181.891 171.036 96.997  1.00 115.09 ? 76  ASP D OD1 1 
ATOM   14735 O OD2 . ASP D 1 76  ? 182.205 173.177 96.606  1.00 115.34 ? 76  ASP D OD2 1 
ATOM   14736 N N   . ARG D 1 77  ? 180.043 169.174 95.967  1.00 109.43 ? 77  ARG D N   1 
ATOM   14737 C CA  . ARG D 1 77  ? 179.089 168.185 96.498  1.00 107.82 ? 77  ARG D CA  1 
ATOM   14738 C C   . ARG D 1 77  ? 177.626 168.559 96.272  1.00 107.81 ? 77  ARG D C   1 
ATOM   14739 O O   . ARG D 1 77  ? 176.858 167.736 95.784  1.00 108.19 ? 77  ARG D O   1 
ATOM   14740 C CB  . ARG D 1 77  ? 179.406 167.951 97.986  1.00 107.25 ? 77  ARG D CB  1 
ATOM   14741 C CG  . ARG D 1 77  ? 178.292 167.209 98.734  1.00 107.65 ? 77  ARG D CG  1 
ATOM   14742 C CD  . ARG D 1 77  ? 178.743 166.581 100.054 1.00 107.52 ? 77  ARG D CD  1 
ATOM   14743 N NE  . ARG D 1 77  ? 179.536 167.487 100.902 1.00 108.01 ? 77  ARG D NE  1 
ATOM   14744 C CZ  . ARG D 1 77  ? 179.157 168.105 102.004 1.00 108.37 ? 77  ARG D CZ  1 
ATOM   14745 N NH1 . ARG D 1 77  ? 180.034 168.729 102.729 1.00 108.42 ? 77  ARG D NH1 1 
ATOM   14746 N NH2 . ARG D 1 77  ? 177.921 168.136 102.401 1.00 107.36 ? 77  ARG D NH2 1 
ATOM   14747 N N   . ASP D 1 78  ? 177.238 169.790 96.590  1.00 109.09 ? 78  ASP D N   1 
ATOM   14748 C CA  . ASP D 1 78  ? 175.843 170.236 96.489  1.00 109.11 ? 78  ASP D CA  1 
ATOM   14749 C C   . ASP D 1 78  ? 175.338 170.308 95.036  1.00 108.60 ? 78  ASP D C   1 
ATOM   14750 O O   . ASP D 1 78  ? 174.161 170.066 94.781  1.00 107.75 ? 78  ASP D O   1 
ATOM   14751 C CB  . ASP D 1 78  ? 175.679 171.582 97.208  1.00 109.08 ? 78  ASP D CB  1 
ATOM   14752 C CG  . ASP D 1 78  ? 176.053 171.523 98.696  1.00 108.73 ? 78  ASP D CG  1 
ATOM   14753 O OD1 . ASP D 1 78  ? 175.870 170.467 99.334  1.00 108.59 ? 78  ASP D OD1 1 
ATOM   14754 O OD2 . ASP D 1 78  ? 176.521 172.549 99.231  1.00 108.76 ? 78  ASP D OD2 1 
ATOM   14755 N N   . ARG D 1 79  ? 176.230 170.571 94.069  1.00 111.67 ? 79  ARG D N   1 
ATOM   14756 C CA  . ARG D 1 79  ? 175.943 170.405 92.634  1.00 113.14 ? 79  ARG D CA  1 
ATOM   14757 C C   . ARG D 1 79  ? 175.820 168.925 92.304  1.00 113.16 ? 79  ARG D C   1 
ATOM   14758 O O   . ARG D 1 79  ? 174.787 168.490 91.796  1.00 112.36 ? 79  ARG D O   1 
ATOM   14759 C CB  . ARG D 1 79  ? 177.028 171.108 91.790  1.00 113.00 ? 79  ARG D CB  1 
ATOM   14760 C CG  . ARG D 1 79  ? 176.881 170.888 90.277  1.00 112.19 ? 79  ARG D CG  1 
ATOM   14761 C CD  . ARG D 1 79  ? 177.992 171.611 89.502  1.00 111.84 ? 79  ARG D CD  1 
ATOM   14762 N NE  . ARG D 1 79  ? 178.062 171.155 88.099  1.00 113.72 ? 79  ARG D NE  1 
ATOM   14763 C CZ  . ARG D 1 79  ? 177.993 171.883 87.002  1.00 113.09 ? 79  ARG D CZ  1 
ATOM   14764 N NH1 . ARG D 1 79  ? 178.064 171.322 85.833  1.00 112.24 ? 79  ARG D NH1 1 
ATOM   14765 N NH2 . ARG D 1 79  ? 177.865 173.174 87.034  1.00 112.29 ? 79  ARG D NH2 1 
ATOM   14766 N N   . LEU D 1 80  ? 176.836 168.124 92.637  1.00 109.89 ? 80  LEU D N   1 
ATOM   14767 C CA  . LEU D 1 80  ? 176.919 166.697 92.306  1.00 108.95 ? 80  LEU D CA  1 
ATOM   14768 C C   . LEU D 1 80  ? 175.715 165.888 92.806  1.00 108.06 ? 80  LEU D C   1 
ATOM   14769 O O   . LEU D 1 80  ? 175.079 165.177 92.032  1.00 108.57 ? 80  LEU D O   1 
ATOM   14770 C CB  . LEU D 1 80  ? 178.245 166.151 92.872  1.00 108.09 ? 80  LEU D CB  1 
ATOM   14771 C CG  . LEU D 1 80  ? 178.465 164.653 92.624  1.00 108.19 ? 80  LEU D CG  1 
ATOM   14772 C CD1 . LEU D 1 80  ? 178.455 164.312 91.139  1.00 108.96 ? 80  LEU D CD1 1 
ATOM   14773 C CD2 . LEU D 1 80  ? 179.808 164.241 93.208  1.00 107.98 ? 80  LEU D CD2 1 
ATOM   14774 N N   . PHE D 1 81  ? 175.354 166.031 94.080  1.00 101.81 ? 81  PHE D N   1 
ATOM   14775 C CA  . PHE D 1 81  ? 174.181 165.376 94.671  1.00 101.83 ? 81  PHE D CA  1 
ATOM   14776 C C   . PHE D 1 81  ? 172.861 165.773 93.991  1.00 103.63 ? 81  PHE D C   1 
ATOM   14777 O O   . PHE D 1 81  ? 171.896 165.008 94.024  1.00 102.72 ? 81  PHE D O   1 
ATOM   14778 C CB  . PHE D 1 81  ? 174.117 165.723 96.160  1.00 100.91 ? 81  PHE D CB  1 
ATOM   14779 C CG  . PHE D 1 81  ? 175.141 165.071 97.071  1.00 102.04 ? 81  PHE D CG  1 
ATOM   14780 C CD1 . PHE D 1 81  ? 176.105 164.148 96.610  1.00 101.54 ? 81  PHE D CD1 1 
ATOM   14781 C CD2 . PHE D 1 81  ? 175.079 165.372 98.443  1.00 102.30 ? 81  PHE D CD2 1 
ATOM   14782 C CE1 . PHE D 1 81  ? 176.975 163.526 97.520  1.00 101.23 ? 81  PHE D CE1 1 
ATOM   14783 C CE2 . PHE D 1 81  ? 175.948 164.744 99.349  1.00 101.18 ? 81  PHE D CE2 1 
ATOM   14784 C CZ  . PHE D 1 81  ? 176.887 163.810 98.890  1.00 101.26 ? 81  PHE D CZ  1 
ATOM   14785 N N   . SER D 1 82  ? 172.803 166.941 93.350  1.00 107.93 ? 82  SER D N   1 
ATOM   14786 C CA  . SER D 1 82  ? 171.635 167.346 92.564  1.00 107.33 ? 82  SER D CA  1 
ATOM   14787 C C   . SER D 1 82  ? 171.627 166.672 91.185  1.00 106.80 ? 82  SER D C   1 
ATOM   14788 O O   . SER D 1 82  ? 170.589 166.178 90.747  1.00 106.41 ? 82  SER D O   1 
ATOM   14789 C CB  . SER D 1 82  ? 171.609 168.875 92.451  1.00 107.69 ? 82  SER D CB  1 
ATOM   14790 O OG  . SER D 1 82  ? 170.355 169.341 91.992  1.00 107.59 ? 82  SER D OG  1 
ATOM   14791 N N   . VAL D 1 83  ? 172.802 166.530 90.557  1.00 105.97 ? 83  VAL D N   1 
ATOM   14792 C CA  . VAL D 1 83  ? 172.972 165.805 89.285  1.00 106.99 ? 83  VAL D CA  1 
ATOM   14793 C C   . VAL D 1 83  ? 172.647 164.316 89.420  1.00 107.18 ? 83  VAL D C   1 
ATOM   14794 O O   . VAL D 1 83  ? 171.899 163.793 88.602  1.00 106.68 ? 83  VAL D O   1 
ATOM   14795 C CB  . VAL D 1 83  ? 174.392 165.975 88.710  1.00 107.33 ? 83  VAL D CB  1 
ATOM   14796 C CG1 . VAL D 1 83  ? 174.551 165.246 87.370  1.00 107.66 ? 83  VAL D CG1 1 
ATOM   14797 C CG2 . VAL D 1 83  ? 174.716 167.446 88.467  1.00 107.11 ? 83  VAL D CG2 1 
ATOM   14798 N N   . VAL D 1 84  ? 173.143 163.619 90.452  1.00 100.60 ? 84  VAL D N   1 
ATOM   14799 C CA  . VAL D 1 84  ? 172.924 162.162 90.579  1.00 99.16  ? 84  VAL D CA  1 
ATOM   14800 C C   . VAL D 1 84  ? 171.457 161.753 90.766  1.00 98.71  ? 84  VAL D C   1 
ATOM   14801 O O   . VAL D 1 84  ? 171.124 160.591 90.560  1.00 98.07  ? 84  VAL D O   1 
ATOM   14802 C CB  . VAL D 1 84  ? 173.797 161.508 91.663  1.00 97.82  ? 84  VAL D CB  1 
ATOM   14803 C CG1 . VAL D 1 84  ? 175.283 161.802 91.480  1.00 97.74  ? 84  VAL D CG1 1 
ATOM   14804 C CG2 . VAL D 1 84  ? 173.388 161.885 93.083  1.00 97.36  ? 84  VAL D CG2 1 
ATOM   14805 N N   . SER D 1 85  ? 170.564 162.677 91.127  1.00 102.32 ? 85  SER D N   1 
ATOM   14806 C CA  . SER D 1 85  ? 169.114 162.444 91.187  1.00 102.53 ? 85  SER D CA  1 
ATOM   14807 C C   . SER D 1 85  ? 168.375 162.741 89.860  1.00 103.46 ? 85  SER D C   1 
ATOM   14808 O O   . SER D 1 85  ? 167.231 162.316 89.681  1.00 102.75 ? 85  SER D O   1 
ATOM   14809 C CB  . SER D 1 85  ? 168.542 163.258 92.355  1.00 101.12 ? 85  SER D CB  1 
ATOM   14810 O OG  . SER D 1 85  ? 167.181 162.961 92.583  1.00 101.53 ? 85  SER D OG  1 
ATOM   14811 N N   . ARG D 1 86  ? 169.055 163.385 88.893  1.00 109.96 ? 86  ARG D N   1 
ATOM   14812 C CA  . ARG D 1 86  ? 168.430 163.726 87.572  1.00 111.01 ? 86  ARG D CA  1 
ATOM   14813 C C   . ARG D 1 86  ? 168.614 162.597 86.558  1.00 112.11 ? 86  ARG D C   1 
ATOM   14814 O O   . ARG D 1 86  ? 169.587 161.830 86.691  1.00 110.05 ? 86  ARG D O   1 
ATOM   14815 C CB  . ARG D 1 86  ? 168.995 165.045 87.000  1.00 111.50 ? 86  ARG D CB  1 
ATOM   14816 C CG  . ARG D 1 86  ? 168.260 166.258 87.578  1.00 110.38 ? 86  ARG D CG  1 
ATOM   14817 C CD  . ARG D 1 86  ? 168.774 167.576 87.029  1.00 110.85 ? 86  ARG D CD  1 
ATOM   14818 N NE  . ARG D 1 86  ? 170.144 167.873 87.424  1.00 111.18 ? 86  ARG D NE  1 
ATOM   14819 C CZ  . ARG D 1 86  ? 170.481 168.522 88.532  1.00 110.34 ? 86  ARG D CZ  1 
ATOM   14820 N NH1 . ARG D 1 86  ? 171.754 168.753 88.803  1.00 110.51 ? 86  ARG D NH1 1 
ATOM   14821 N NH2 . ARG D 1 86  ? 169.546 168.937 89.367  1.00 109.54 ? 86  ARG D NH2 1 
ATOM   14822 N N   . GLY D 1 87  ? 167.710 162.514 85.587  1.00 117.59 ? 87  GLY D N   1 
ATOM   14823 C CA  . GLY D 1 87  ? 167.728 161.522 84.504  1.00 116.19 ? 87  GLY D CA  1 
ATOM   14824 C C   . GLY D 1 87  ? 168.755 161.792 83.393  1.00 116.91 ? 87  GLY D C   1 
ATOM   14825 O O   . GLY D 1 87  ? 169.019 160.910 82.580  1.00 116.95 ? 87  GLY D O   1 
ATOM   14826 N N   . VAL D 1 88  ? 169.354 162.988 83.362  1.00 119.52 ? 88  VAL D N   1 
ATOM   14827 C CA  . VAL D 1 88  ? 170.448 163.353 82.444  1.00 120.18 ? 88  VAL D CA  1 
ATOM   14828 C C   . VAL D 1 88  ? 171.783 163.481 83.202  1.00 119.70 ? 88  VAL D C   1 
ATOM   14829 O O   . VAL D 1 88  ? 171.895 164.314 84.102  1.00 118.63 ? 88  VAL D O   1 
ATOM   14830 C CB  . VAL D 1 88  ? 170.135 164.638 81.647  1.00 119.64 ? 88  VAL D CB  1 
ATOM   14831 C CG1 . VAL D 1 88  ? 169.175 164.324 80.501  1.00 118.55 ? 88  VAL D CG1 1 
ATOM   14832 C CG2 . VAL D 1 88  ? 169.535 165.785 82.468  1.00 118.97 ? 88  VAL D CG2 1 
ATOM   14833 N N   . PRO D 1 89  ? 172.821 162.701 82.850  1.00 117.63 ? 89  PRO D N   1 
ATOM   14834 C CA  . PRO D 1 89  ? 174.131 162.760 83.503  1.00 117.44 ? 89  PRO D CA  1 
ATOM   14835 C C   . PRO D 1 89  ? 175.082 163.840 82.951  1.00 118.00 ? 89  PRO D C   1 
ATOM   14836 O O   . PRO D 1 89  ? 176.162 164.029 83.500  1.00 117.15 ? 89  PRO D O   1 
ATOM   14837 C CB  . PRO D 1 89  ? 174.718 161.367 83.295  1.00 115.87 ? 89  PRO D CB  1 
ATOM   14838 C CG  . PRO D 1 89  ? 174.168 160.957 81.932  1.00 115.67 ? 89  PRO D CG  1 
ATOM   14839 C CD  . PRO D 1 89  ? 172.769 161.565 81.937  1.00 115.86 ? 89  PRO D CD  1 
ATOM   14840 N N   . GLU D 1 90  ? 174.740 164.549 81.870  1.00 117.58 ? 90  GLU D N   1 
ATOM   14841 C CA  . GLU D 1 90  ? 175.695 165.430 81.177  1.00 117.59 ? 90  GLU D CA  1 
ATOM   14842 C C   . GLU D 1 90  ? 176.240 166.579 82.042  1.00 117.74 ? 90  GLU D C   1 
ATOM   14843 O O   . GLU D 1 90  ? 177.347 167.069 81.818  1.00 117.52 ? 90  GLU D O   1 
ATOM   14844 C CB  . GLU D 1 90  ? 175.034 166.005 79.911  1.00 117.25 ? 90  GLU D CB  1 
ATOM   14845 C CG  . GLU D 1 90  ? 174.460 164.956 78.941  1.00 117.18 ? 90  GLU D CG  1 
ATOM   14846 C CD  . GLU D 1 90  ? 175.482 163.950 78.386  1.00 117.73 ? 90  GLU D CD  1 
ATOM   14847 O OE1 . GLU D 1 90  ? 176.705 164.214 78.423  1.00 117.23 ? 90  GLU D OE1 1 
ATOM   14848 O OE2 . GLU D 1 90  ? 175.053 162.894 77.877  1.00 117.08 ? 90  GLU D OE2 1 
ATOM   14849 N N   . GLU D 1 91  ? 175.503 166.990 83.076  1.00 114.74 ? 91  GLU D N   1 
ATOM   14850 C CA  . GLU D 1 91  ? 175.924 168.031 84.024  1.00 115.05 ? 91  GLU D CA  1 
ATOM   14851 C C   . GLU D 1 91  ? 177.156 167.621 84.861  1.00 114.93 ? 91  GLU D C   1 
ATOM   14852 O O   . GLU D 1 91  ? 177.797 168.483 85.464  1.00 114.87 ? 91  GLU D O   1 
ATOM   14853 C CB  . GLU D 1 91  ? 174.703 168.438 84.868  1.00 114.36 ? 91  GLU D CB  1 
ATOM   14854 C CG  . GLU D 1 91  ? 174.918 169.719 85.691  1.00 114.52 ? 91  GLU D CG  1 
ATOM   14855 C CD  . GLU D 1 91  ? 173.631 170.291 86.314  1.00 114.80 ? 91  GLU D CD  1 
ATOM   14856 O OE1 . GLU D 1 91  ? 172.555 169.652 86.256  1.00 114.73 ? 91  GLU D OE1 1 
ATOM   14857 O OE2 . GLU D 1 91  ? 173.696 171.398 86.885  1.00 113.93 ? 91  GLU D OE2 1 
ATOM   14858 N N   . LEU D 1 92  ? 177.561 166.340 84.839  1.00 114.17 ? 92  LEU D N   1 
ATOM   14859 C CA  . LEU D 1 92  ? 178.844 165.856 85.368  1.00 114.97 ? 92  LEU D CA  1 
ATOM   14860 C C   . LEU D 1 92  ? 180.072 166.374 84.592  1.00 114.75 ? 92  LEU D C   1 
ATOM   14861 O O   . LEU D 1 92  ? 181.194 166.246 85.078  1.00 114.30 ? 92  LEU D O   1 
ATOM   14862 C CB  . LEU D 1 92  ? 178.883 164.314 85.358  1.00 115.20 ? 92  LEU D CB  1 
ATOM   14863 C CG  . LEU D 1 92  ? 177.853 163.584 86.235  1.00 115.12 ? 92  LEU D CG  1 
ATOM   14864 C CD1 . LEU D 1 92  ? 177.991 162.091 85.989  1.00 113.63 ? 92  LEU D CD1 1 
ATOM   14865 C CD2 . LEU D 1 92  ? 178.048 163.840 87.726  1.00 113.56 ? 92  LEU D CD2 1 
ATOM   14866 N N   . THR D 1 93  ? 179.907 166.927 83.387  1.00 116.02 ? 93  THR D N   1 
ATOM   14867 C CA  . THR D 1 93  ? 181.040 167.432 82.584  1.00 115.27 ? 93  THR D CA  1 
ATOM   14868 C C   . THR D 1 93  ? 181.849 168.494 83.341  1.00 116.21 ? 93  THR D C   1 
ATOM   14869 O O   . THR D 1 93  ? 181.298 169.446 83.893  1.00 116.61 ? 93  THR D O   1 
ATOM   14870 C CB  . THR D 1 93  ? 180.584 167.960 81.216  1.00 114.55 ? 93  THR D CB  1 
ATOM   14871 O OG1 . THR D 1 93  ? 179.424 168.756 81.304  1.00 114.62 ? 93  THR D OG1 1 
ATOM   14872 C CG2 . THR D 1 93  ? 180.278 166.817 80.257  1.00 114.86 ? 93  THR D CG2 1 
ATOM   14873 N N   . GLY D 1 94  ? 183.171 168.310 83.405  1.00 116.70 ? 94  GLY D N   1 
ATOM   14874 C CA  . GLY D 1 94  ? 184.090 169.098 84.238  1.00 116.50 ? 94  GLY D CA  1 
ATOM   14875 C C   . GLY D 1 94  ? 184.494 168.435 85.565  1.00 117.33 ? 94  GLY D C   1 
ATOM   14876 O O   . GLY D 1 94  ? 185.486 168.851 86.170  1.00 117.01 ? 94  GLY D O   1 
ATOM   14877 N N   . LEU D 1 95  ? 183.758 167.421 86.046  1.00 117.26 ? 95  LEU D N   1 
ATOM   14878 C CA  . LEU D 1 95  ? 184.022 166.760 87.337  1.00 116.27 ? 95  LEU D CA  1 
ATOM   14879 C C   . LEU D 1 95  ? 185.353 165.993 87.345  1.00 115.86 ? 95  LEU D C   1 
ATOM   14880 O O   . LEU D 1 95  ? 186.148 166.174 88.263  1.00 115.25 ? 95  LEU D O   1 
ATOM   14881 C CB  . LEU D 1 95  ? 182.833 165.845 87.686  1.00 115.55 ? 95  LEU D CB  1 
ATOM   14882 C CG  . LEU D 1 95  ? 182.960 165.023 88.981  1.00 116.35 ? 95  LEU D CG  1 
ATOM   14883 C CD1 . LEU D 1 95  ? 183.142 165.879 90.231  1.00 115.36 ? 95  LEU D CD1 1 
ATOM   14884 C CD2 . LEU D 1 95  ? 181.683 164.211 89.158  1.00 115.43 ? 95  LEU D CD2 1 
ATOM   14885 N N   . LEU D 1 96  ? 185.611 165.183 86.319  1.00 116.63 ? 96  LEU D N   1 
ATOM   14886 C CA  . LEU D 1 96  ? 186.869 164.449 86.199  1.00 117.64 ? 96  LEU D CA  1 
ATOM   14887 C C   . LEU D 1 96  ? 188.069 165.407 86.117  1.00 118.75 ? 96  LEU D C   1 
ATOM   14888 O O   . LEU D 1 96  ? 189.073 165.187 86.791  1.00 118.59 ? 96  LEU D O   1 
ATOM   14889 C CB  . LEU D 1 96  ? 186.773 163.517 84.981  1.00 117.16 ? 96  LEU D CB  1 
ATOM   14890 C CG  . LEU D 1 96  ? 188.053 162.717 84.690  1.00 117.58 ? 96  LEU D CG  1 
ATOM   14891 C CD1 . LEU D 1 96  ? 188.448 161.800 85.846  1.00 116.49 ? 96  LEU D CD1 1 
ATOM   14892 C CD2 . LEU D 1 96  ? 187.828 161.871 83.441  1.00 116.98 ? 96  LEU D CD2 1 
ATOM   14893 N N   . GLU D 1 97  ? 187.960 166.499 85.354  1.00 118.70 ? 97  GLU D N   1 
ATOM   14894 C CA  . GLU D 1 97  ? 188.982 167.538 85.268  1.00 118.25 ? 97  GLU D CA  1 
ATOM   14895 C C   . GLU D 1 97  ? 189.252 168.186 86.634  1.00 118.29 ? 97  GLU D C   1 
ATOM   14896 O O   . GLU D 1 97  ? 190.409 168.309 87.037  1.00 117.53 ? 97  GLU D O   1 
ATOM   14897 C CB  . GLU D 1 97  ? 188.580 168.606 84.238  1.00 118.30 ? 97  GLU D CB  1 
ATOM   14898 C CG  . GLU D 1 97  ? 188.415 168.072 82.805  1.00 118.56 ? 97  GLU D CG  1 
ATOM   14899 C CD  . GLU D 1 97  ? 186.968 167.709 82.424  1.00 118.47 ? 97  GLU D CD  1 
ATOM   14900 O OE1 . GLU D 1 97  ? 186.264 167.055 83.225  1.00 117.38 ? 97  GLU D OE1 1 
ATOM   14901 O OE2 . GLU D 1 97  ? 186.544 168.074 81.309  1.00 118.49 ? 97  GLU D OE2 1 
ATOM   14902 N N   . TYR D 1 98  ? 188.209 168.547 87.385  1.00 119.30 ? 98  TYR D N   1 
ATOM   14903 C CA  . TYR D 1 98  ? 188.374 169.161 88.703  1.00 119.54 ? 98  TYR D CA  1 
ATOM   14904 C C   . TYR D 1 98  ? 188.936 168.190 89.752  1.00 119.53 ? 98  TYR D C   1 
ATOM   14905 O O   . TYR D 1 98  ? 189.861 168.543 90.482  1.00 119.13 ? 98  TYR D O   1 
ATOM   14906 C CB  . TYR D 1 98  ? 187.046 169.763 89.166  1.00 118.86 ? 98  TYR D CB  1 
ATOM   14907 C CG  . TYR D 1 98  ? 187.183 170.540 90.456  1.00 119.31 ? 98  TYR D CG  1 
ATOM   14908 C CD1 . TYR D 1 98  ? 187.936 171.727 90.482  1.00 119.44 ? 98  TYR D CD1 1 
ATOM   14909 C CD2 . TYR D 1 98  ? 186.596 170.064 91.641  1.00 119.34 ? 98  TYR D CD2 1 
ATOM   14910 C CE1 . TYR D 1 98  ? 188.097 172.441 91.685  1.00 119.27 ? 98  TYR D CE1 1 
ATOM   14911 C CE2 . TYR D 1 98  ? 186.747 170.782 92.844  1.00 119.27 ? 98  TYR D CE2 1 
ATOM   14912 C CZ  . TYR D 1 98  ? 187.499 171.973 92.868  1.00 119.24 ? 98  TYR D CZ  1 
ATOM   14913 O OH  . TYR D 1 98  ? 187.632 172.680 94.019  1.00 119.59 ? 98  TYR D OH  1 
ATOM   14914 N N   . LEU D 1 99  ? 188.435 166.953 89.800  1.00 118.21 ? 99  LEU D N   1 
ATOM   14915 C CA  . LEU D 1 99  ? 188.950 165.902 90.682  1.00 118.72 ? 99  LEU D CA  1 
ATOM   14916 C C   . LEU D 1 99  ? 190.427 165.596 90.395  1.00 118.30 ? 99  LEU D C   1 
ATOM   14917 O O   . LEU D 1 99  ? 191.255 165.619 91.306  1.00 117.34 ? 99  LEU D O   1 
ATOM   14918 C CB  . LEU D 1 99  ? 188.110 164.626 90.495  1.00 118.65 ? 99  LEU D CB  1 
ATOM   14919 C CG  . LEU D 1 99  ? 186.700 164.672 91.106  1.00 118.03 ? 99  LEU D CG  1 
ATOM   14920 C CD1 . LEU D 1 99  ? 185.932 163.431 90.653  1.00 116.65 ? 99  LEU D CD1 1 
ATOM   14921 C CD2 . LEU D 1 99  ? 186.713 164.688 92.632  1.00 117.05 ? 99  LEU D CD2 1 
ATOM   14922 N N   . ARG D 1 100 ? 190.768 165.335 89.129  1.00 119.31 ? 100 ARG D N   1 
ATOM   14923 C CA  . ARG D 1 100 ? 192.106 164.871 88.723  1.00 119.54 ? 100 ARG D CA  1 
ATOM   14924 C C   . ARG D 1 100 ? 193.152 165.992 88.677  1.00 119.57 ? 100 ARG D C   1 
ATOM   14925 O O   . ARG D 1 100 ? 194.331 165.721 88.893  1.00 118.82 ? 100 ARG D O   1 
ATOM   14926 C CB  . ARG D 1 100 ? 191.956 164.100 87.398  1.00 119.18 ? 100 ARG D CB  1 
ATOM   14927 C CG  . ARG D 1 100 ? 193.147 163.190 87.072  1.00 118.90 ? 100 ARG D CG  1 
ATOM   14928 C CD  . ARG D 1 100 ? 192.774 162.123 86.034  1.00 118.50 ? 100 ARG D CD  1 
ATOM   14929 N NE  . ARG D 1 100 ? 192.378 162.703 84.742  1.00 119.54 ? 100 ARG D NE  1 
ATOM   14930 C CZ  . ARG D 1 100 ? 191.907 162.052 83.695  1.00 119.45 ? 100 ARG D CZ  1 
ATOM   14931 N NH1 . ARG D 1 100 ? 191.652 162.687 82.591  1.00 118.72 ? 100 ARG D NH1 1 
ATOM   14932 N NH2 . ARG D 1 100 ? 191.671 160.773 83.711  1.00 118.79 ? 100 ARG D NH2 1 
ATOM   14933 N N   . TRP D 1 101 ? 192.745 167.249 88.476  1.00 122.09 ? 101 TRP D N   1 
ATOM   14934 C CA  . TRP D 1 101 ? 193.629 168.415 88.598  1.00 122.35 ? 101 TRP D CA  1 
ATOM   14935 C C   . TRP D 1 101 ? 193.868 168.863 90.049  1.00 122.56 ? 101 TRP D C   1 
ATOM   14936 O O   . TRP D 1 101 ? 194.932 169.407 90.350  1.00 122.61 ? 101 TRP D O   1 
ATOM   14937 C CB  . TRP D 1 101 ? 193.041 169.571 87.798  1.00 121.13 ? 101 TRP D CB  1 
ATOM   14938 N N   . ASN D 1 102 ? 192.918 168.630 90.965  1.00 121.10 ? 102 ASN D N   1 
ATOM   14939 C CA  . ASN D 1 102 ? 193.046 168.971 92.389  1.00 120.92 ? 102 ASN D CA  1 
ATOM   14940 C C   . ASN D 1 102 ? 193.436 167.768 93.283  1.00 121.31 ? 102 ASN D C   1 
ATOM   14941 O O   . ASN D 1 102 ? 193.463 167.899 94.504  1.00 120.65 ? 102 ASN D O   1 
ATOM   14942 C CB  . ASN D 1 102 ? 191.748 169.672 92.843  1.00 121.43 ? 102 ASN D CB  1 
ATOM   14943 C CG  . ASN D 1 102 ? 191.908 170.574 94.060  1.00 121.61 ? 102 ASN D CG  1 
ATOM   14944 O OD1 . ASN D 1 102 ? 191.152 170.513 95.017  1.00 121.74 ? 102 ASN D OD1 1 
ATOM   14945 N ND2 . ASN D 1 102 ? 192.873 171.458 94.069  1.00 120.82 ? 102 ASN D ND2 1 
ATOM   14946 N N   . SER D 1 103 ? 193.751 166.611 92.687  1.00 120.75 ? 103 SER D N   1 
ATOM   14947 C CA  . SER D 1 103 ? 194.181 165.373 93.366  1.00 120.64 ? 103 SER D CA  1 
ATOM   14948 C C   . SER D 1 103 ? 193.186 164.852 94.416  1.00 120.86 ? 103 SER D C   1 
ATOM   14949 O O   . SER D 1 103 ? 193.557 164.560 95.557  1.00 119.69 ? 103 SER D O   1 
ATOM   14950 C CB  . SER D 1 103 ? 195.611 165.505 93.916  1.00 120.25 ? 103 SER D CB  1 
ATOM   14951 O OG  . SER D 1 103 ? 196.512 165.831 92.875  1.00 120.01 ? 103 SER D OG  1 
ATOM   14952 N N   . LYS D 1 104 ? 191.906 164.754 94.030  1.00 118.71 ? 104 LYS D N   1 
ATOM   14953 C CA  . LYS D 1 104 ? 190.764 164.362 94.879  1.00 118.04 ? 104 LYS D CA  1 
ATOM   14954 C C   . LYS D 1 104 ? 189.905 163.277 94.228  1.00 118.00 ? 104 LYS D C   1 
ATOM   14955 O O   . LYS D 1 104 ? 189.947 163.092 93.014  1.00 117.40 ? 104 LYS D O   1 
ATOM   14956 C CB  . LYS D 1 104 ? 189.908 165.595 95.210  1.00 117.33 ? 104 LYS D CB  1 
ATOM   14957 C CG  . LYS D 1 104 ? 190.554 166.438 96.313  1.00 117.46 ? 104 LYS D CG  1 
ATOM   14958 C CD  . LYS D 1 104 ? 189.786 167.736 96.555  1.00 118.29 ? 104 LYS D CD  1 
ATOM   14959 C CE  . LYS D 1 104 ? 190.508 168.550 97.634  1.00 118.23 ? 104 LYS D CE  1 
ATOM   14960 N NZ  . LYS D 1 104 ? 190.052 169.955 97.658  1.00 116.88 ? 104 LYS D NZ  1 
ATOM   14961 N N   . TYR D 1 105 ? 189.108 162.579 95.032  1.00 113.16 ? 105 TYR D N   1 
ATOM   14962 C CA  . TYR D 1 105 ? 188.265 161.452 94.613  1.00 112.44 ? 105 TYR D CA  1 
ATOM   14963 C C   . TYR D 1 105 ? 186.855 161.520 95.220  1.00 111.33 ? 105 TYR D C   1 
ATOM   14964 O O   . TYR D 1 105 ? 186.652 162.078 96.297  1.00 110.97 ? 105 TYR D O   1 
ATOM   14965 C CB  . TYR D 1 105 ? 188.929 160.127 95.012  1.00 111.65 ? 105 TYR D CB  1 
ATOM   14966 C CG  . TYR D 1 105 ? 190.422 160.027 94.774  1.00 112.52 ? 105 TYR D CG  1 
ATOM   14967 C CD1 . TYR D 1 105 ? 190.931 159.992 93.463  1.00 112.11 ? 105 TYR D CD1 1 
ATOM   14968 C CD2 . TYR D 1 105 ? 191.306 159.974 95.866  1.00 111.75 ? 105 TYR D CD2 1 
ATOM   14969 C CE1 . TYR D 1 105 ? 192.317 159.894 93.251  1.00 111.96 ? 105 TYR D CE1 1 
ATOM   14970 C CE2 . TYR D 1 105 ? 192.691 159.869 95.656  1.00 112.68 ? 105 TYR D CE2 1 
ATOM   14971 C CZ  . TYR D 1 105 ? 193.201 159.832 94.342  1.00 112.53 ? 105 TYR D CZ  1 
ATOM   14972 O OH  . TYR D 1 105 ? 194.537 159.749 94.126  1.00 111.09 ? 105 TYR D OH  1 
ATOM   14973 N N   . LEU D 1 106 ? 185.873 160.877 94.584  1.00 104.46 ? 106 LEU D N   1 
ATOM   14974 C CA  . LEU D 1 106 ? 184.489 160.826 95.078  1.00 103.94 ? 106 LEU D CA  1 
ATOM   14975 C C   . LEU D 1 106 ? 184.321 160.076 96.417  1.00 104.37 ? 106 LEU D C   1 
ATOM   14976 O O   . LEU D 1 106 ? 183.318 160.266 97.099  1.00 104.37 ? 106 LEU D O   1 
ATOM   14977 C CB  . LEU D 1 106 ? 183.596 160.219 93.985  1.00 103.68 ? 106 LEU D CB  1 
ATOM   14978 C CG  . LEU D 1 106 ? 183.499 161.068 92.706  1.00 103.78 ? 106 LEU D CG  1 
ATOM   14979 C CD1 . LEU D 1 106 ? 182.642 160.368 91.656  1.00 103.65 ? 106 LEU D CD1 1 
ATOM   14980 C CD2 . LEU D 1 106 ? 182.885 162.434 93.001  1.00 104.92 ? 106 LEU D CD2 1 
ATOM   14981 N N   . THR D 1 107 ? 185.298 159.257 96.823  1.00 106.89 ? 107 THR D N   1 
ATOM   14982 C CA  . THR D 1 107 ? 185.348 158.606 98.148  1.00 106.88 ? 107 THR D CA  1 
ATOM   14983 C C   . THR D 1 107 ? 185.836 159.551 99.261  1.00 106.69 ? 107 THR D C   1 
ATOM   14984 O O   . THR D 1 107 ? 185.673 159.248 100.443 1.00 106.20 ? 107 THR D O   1 
ATOM   14985 C CB  . THR D 1 107 ? 186.219 157.332 98.092  1.00 107.43 ? 107 THR D CB  1 
ATOM   14986 O OG1 . THR D 1 107 ? 185.714 156.456 97.115  1.00 107.14 ? 107 THR D OG1 1 
ATOM   14987 C CG2 . THR D 1 107 ? 186.250 156.505 99.374  1.00 106.27 ? 107 THR D CG2 1 
ATOM   14988 N N   . ASP D 1 108 ? 186.432 160.701 98.931  1.00 110.99 ? 108 ASP D N   1 
ATOM   14989 C CA  . ASP D 1 108 ? 186.935 161.662 99.929  1.00 110.82 ? 108 ASP D CA  1 
ATOM   14990 C C   . ASP D 1 108 ? 185.796 162.332 100.710 1.00 110.07 ? 108 ASP D C   1 
ATOM   14991 O O   . ASP D 1 108 ? 184.735 162.618 100.156 1.00 110.29 ? 108 ASP D O   1 
ATOM   14992 C CB  . ASP D 1 108 ? 187.805 162.750 99.279  1.00 110.68 ? 108 ASP D CB  1 
ATOM   14993 C CG  . ASP D 1 108 ? 189.081 162.233 98.605  1.00 110.92 ? 108 ASP D CG  1 
ATOM   14994 O OD1 . ASP D 1 108 ? 189.556 161.136 98.965  1.00 110.70 ? 108 ASP D OD1 1 
ATOM   14995 O OD2 . ASP D 1 108 ? 189.645 162.971 97.772  1.00 111.02 ? 108 ASP D OD2 1 
ATOM   14996 N N   . SER D 1 109 ? 186.037 162.650 101.986 1.00 107.64 ? 109 SER D N   1 
ATOM   14997 C CA  . SER D 1 109 ? 185.021 163.174 102.919 1.00 108.90 ? 109 SER D CA  1 
ATOM   14998 C C   . SER D 1 109 ? 184.236 164.374 102.370 1.00 108.21 ? 109 SER D C   1 
ATOM   14999 O O   . SER D 1 109 ? 183.015 164.437 102.529 1.00 107.47 ? 109 SER D O   1 
ATOM   15000 C CB  . SER D 1 109 ? 185.700 163.537 104.246 1.00 107.50 ? 109 SER D CB  1 
ATOM   15001 O OG  . SER D 1 109 ? 184.757 164.004 105.188 1.00 106.76 ? 109 SER D OG  1 
ATOM   15002 N N   . ALA D 1 110 ? 184.898 165.271 101.635 1.00 110.05 ? 110 ALA D N   1 
ATOM   15003 C CA  . ALA D 1 110 ? 184.285 166.440 101.005 1.00 109.78 ? 110 ALA D CA  1 
ATOM   15004 C C   . ALA D 1 110 ? 183.091 166.118 100.082 1.00 110.38 ? 110 ALA D C   1 
ATOM   15005 O O   . ALA D 1 110 ? 182.162 166.918 100.000 1.00 110.68 ? 110 ALA D O   1 
ATOM   15006 C CB  . ALA D 1 110 ? 185.381 167.171 100.226 1.00 108.63 ? 110 ALA D CB  1 
ATOM   15007 N N   . TYR D 1 111 ? 183.080 164.949 99.427  1.00 107.69 ? 111 TYR D N   1 
ATOM   15008 C CA  . TYR D 1 111 ? 182.003 164.496 98.535  1.00 107.38 ? 111 TYR D CA  1 
ATOM   15009 C C   . TYR D 1 111 ? 180.985 163.562 99.225  1.00 106.70 ? 111 TYR D C   1 
ATOM   15010 O O   . TYR D 1 111 ? 180.232 162.856 98.555  1.00 106.91 ? 111 TYR D O   1 
ATOM   15011 C CB  . TYR D 1 111 ? 182.607 163.911 97.248  1.00 107.86 ? 111 TYR D CB  1 
ATOM   15012 C CG  . TYR D 1 111 ? 183.291 164.941 96.366  1.00 108.31 ? 111 TYR D CG  1 
ATOM   15013 C CD1 . TYR D 1 111 ? 182.513 165.776 95.539  1.00 107.74 ? 111 TYR D CD1 1 
ATOM   15014 C CD2 . TYR D 1 111 ? 184.690 165.072 96.369  1.00 109.10 ? 111 TYR D CD2 1 
ATOM   15015 C CE1 . TYR D 1 111 ? 183.127 166.738 94.716  1.00 108.56 ? 111 TYR D CE1 1 
ATOM   15016 C CE2 . TYR D 1 111 ? 185.307 166.050 95.564  1.00 108.60 ? 111 TYR D CE2 1 
ATOM   15017 C CZ  . TYR D 1 111 ? 184.528 166.886 94.737  1.00 109.01 ? 111 TYR D CZ  1 
ATOM   15018 O OH  . TYR D 1 111 ? 185.132 167.838 93.979  1.00 109.27 ? 111 TYR D OH  1 
ATOM   15019 N N   . THR D 1 112 ? 180.911 163.570 100.561 1.00 98.27  ? 112 THR D N   1 
ATOM   15020 C CA  . THR D 1 112 ? 180.002 162.725 101.360 1.00 98.01  ? 112 THR D CA  1 
ATOM   15021 C C   . THR D 1 112 ? 179.001 163.537 102.187 1.00 97.99  ? 112 THR D C   1 
ATOM   15022 O O   . THR D 1 112 ? 179.272 164.683 102.530 1.00 99.37  ? 112 THR D O   1 
ATOM   15023 C CB  . THR D 1 112 ? 180.767 161.766 102.282 1.00 97.28  ? 112 THR D CB  1 
ATOM   15024 O OG1 . THR D 1 112 ? 181.342 162.438 103.377 1.00 97.07  ? 112 THR D OG1 1 
ATOM   15025 C CG2 . THR D 1 112 ? 181.867 160.982 101.577 1.00 96.67  ? 112 THR D CG2 1 
ATOM   15026 N N   . GLU D 1 113 ? 177.861 162.945 102.571 1.00 91.89  ? 113 GLU D N   1 
ATOM   15027 C CA  . GLU D 1 113 ? 176.856 163.611 103.430 1.00 91.95  ? 113 GLU D CA  1 
ATOM   15028 C C   . GLU D 1 113 ? 177.377 163.993 104.835 1.00 91.71  ? 113 GLU D C   1 
ATOM   15029 O O   . GLU D 1 113 ? 176.716 164.739 105.556 1.00 92.32  ? 113 GLU D O   1 
ATOM   15030 C CB  . GLU D 1 113 ? 175.567 162.770 103.550 1.00 90.83  ? 113 GLU D CB  1 
ATOM   15031 C CG  . GLU D 1 113 ? 174.858 162.535 102.206 1.00 92.23  ? 113 GLU D CG  1 
ATOM   15032 C CD  . GLU D 1 113 ? 173.333 162.729 102.265 1.00 93.31  ? 113 GLU D CD  1 
ATOM   15033 O OE1 . GLU D 1 113 ? 172.629 161.928 102.918 1.00 92.52  ? 113 GLU D OE1 1 
ATOM   15034 O OE2 . GLU D 1 113 ? 172.820 163.658 101.599 1.00 93.27  ? 113 GLU D OE2 1 
ATOM   15035 N N   . GLY D 1 114 ? 178.566 163.524 105.228 1.00 85.24  ? 114 GLY D N   1 
ATOM   15036 C CA  . GLY D 1 114 ? 179.324 164.009 106.390 1.00 86.53  ? 114 GLY D CA  1 
ATOM   15037 C C   . GLY D 1 114 ? 178.853 163.502 107.754 1.00 84.79  ? 114 GLY D C   1 
ATOM   15038 O O   . GLY D 1 114 ? 179.672 163.080 108.570 1.00 82.57  ? 114 GLY D O   1 
ATOM   15039 N N   . SER D 1 115 ? 177.543 163.475 107.998 1.00 82.00  ? 115 SER D N   1 
ATOM   15040 C CA  . SER D 1 115 ? 176.946 162.885 109.204 1.00 82.72  ? 115 SER D CA  1 
ATOM   15041 C C   . SER D 1 115 ? 177.103 161.360 109.257 1.00 84.08  ? 115 SER D C   1 
ATOM   15042 O O   . SER D 1 115 ? 177.240 160.791 110.339 1.00 80.97  ? 115 SER D O   1 
ATOM   15043 C CB  . SER D 1 115 ? 175.465 163.274 109.280 1.00 80.42  ? 115 SER D CB  1 
ATOM   15044 O OG  . SER D 1 115 ? 174.765 162.872 108.117 1.00 80.27  ? 115 SER D OG  1 
ATOM   15045 N N   . THR D 1 116 ? 177.132 160.703 108.092 1.00 79.80  ? 116 THR D N   1 
ATOM   15046 C CA  . THR D 1 116 ? 177.225 159.238 107.942 1.00 77.34  ? 116 THR D CA  1 
ATOM   15047 C C   . THR D 1 116 ? 178.375 158.763 107.050 1.00 75.68  ? 116 THR D C   1 
ATOM   15048 O O   . THR D 1 116 ? 178.693 157.580 107.046 1.00 77.45  ? 116 THR D O   1 
ATOM   15049 C CB  . THR D 1 116 ? 175.913 158.679 107.372 1.00 76.51  ? 116 THR D CB  1 
ATOM   15050 O OG1 . THR D 1 116 ? 175.699 159.245 106.097 1.00 76.06  ? 116 THR D OG1 1 
ATOM   15051 C CG2 . THR D 1 116 ? 174.678 159.011 108.205 1.00 76.21  ? 116 THR D CG2 1 
ATOM   15052 N N   . GLY D 1 117 ? 179.025 159.633 106.267 1.00 77.21  ? 117 GLY D N   1 
ATOM   15053 C CA  . GLY D 1 117 ? 180.040 159.169 105.297 1.00 77.79  ? 117 GLY D CA  1 
ATOM   15054 C C   . GLY D 1 117 ? 179.368 158.531 104.089 1.00 77.65  ? 117 GLY D C   1 
ATOM   15055 O O   . GLY D 1 117 ? 179.980 157.624 103.491 1.00 78.08  ? 117 GLY D O   1 
ATOM   15056 N N   . LYS D 1 118 ? 178.157 158.982 103.742 1.00 78.99  ? 118 LYS D N   1 
ATOM   15057 C CA  . LYS D 1 118 ? 177.382 158.416 102.598 1.00 78.36  ? 118 LYS D CA  1 
ATOM   15058 C C   . LYS D 1 118 ? 177.796 159.136 101.320 1.00 78.60  ? 118 LYS D C   1 
ATOM   15059 O O   . LYS D 1 118 ? 177.972 160.365 101.403 1.00 82.27  ? 118 LYS D O   1 
ATOM   15060 C CB  . LYS D 1 118 ? 175.909 158.581 102.928 1.00 78.39  ? 118 LYS D CB  1 
ATOM   15061 C CG  . LYS D 1 118 ? 174.880 158.453 101.801 1.00 79.70  ? 118 LYS D CG  1 
ATOM   15062 C CD  . LYS D 1 118 ? 173.488 158.877 102.212 1.00 80.69  ? 118 LYS D CD  1 
ATOM   15063 C CE  . LYS D 1 118 ? 172.524 158.951 101.047 1.00 80.63  ? 118 LYS D CE  1 
ATOM   15064 N NZ  . LYS D 1 118 ? 171.190 159.438 101.473 1.00 81.28  ? 118 LYS D NZ  1 
ATOM   15065 N N   . THR D 1 119 ? 177.948 158.454 100.185 1.00 80.46  ? 119 THR D N   1 
ATOM   15066 C CA  . THR D 1 119 ? 178.556 158.999 98.951  1.00 80.65  ? 119 THR D CA  1 
ATOM   15067 C C   . THR D 1 119 ? 177.543 159.368 97.860  1.00 79.21  ? 119 THR D C   1 
ATOM   15068 O O   . THR D 1 119 ? 176.363 159.017 97.929  1.00 77.95  ? 119 THR D O   1 
ATOM   15069 C CB  . THR D 1 119 ? 179.585 158.005 98.374  1.00 82.00  ? 119 THR D CB  1 
ATOM   15070 O OG1 . THR D 1 119 ? 178.938 156.851 97.884  1.00 80.18  ? 119 THR D OG1 1 
ATOM   15071 C CG2 . THR D 1 119 ? 180.630 157.561 99.390  1.00 80.48  ? 119 THR D CG2 1 
ATOM   15072 N N   . CYS D 1 120 ? 178.010 160.028 96.799  1.00 85.58  ? 120 CYS D N   1 
ATOM   15073 C CA  . CYS D 1 120 ? 177.225 160.338 95.604  1.00 87.13  ? 120 CYS D CA  1 
ATOM   15074 C C   . CYS D 1 120 ? 176.663 159.083 94.922  1.00 84.99  ? 120 CYS D C   1 
ATOM   15075 O O   . CYS D 1 120 ? 175.524 159.110 94.475  1.00 83.99  ? 120 CYS D O   1 
ATOM   15076 C CB  . CYS D 1 120 ? 178.111 161.145 94.643  1.00 86.44  ? 120 CYS D CB  1 
ATOM   15077 S SG  . CYS D 1 120 ? 179.639 160.238 94.302  1.00 87.55  ? 120 CYS D SG  1 
ATOM   15078 N N   . LEU D 1 121 ? 177.401 157.965 94.900  1.00 80.77  ? 121 LEU D N   1 
ATOM   15079 C CA  . LEU D 1 121 ? 176.909 156.689 94.363  1.00 80.01  ? 121 LEU D CA  1 
ATOM   15080 C C   . LEU D 1 121 ? 175.746 156.134 95.190  1.00 78.17  ? 121 LEU D C   1 
ATOM   15081 O O   . LEU D 1 121 ? 174.739 155.728 94.624  1.00 77.39  ? 121 LEU D O   1 
ATOM   15082 C CB  . LEU D 1 121 ? 178.070 155.687 94.268  1.00 78.46  ? 121 LEU D CB  1 
ATOM   15083 C CG  . LEU D 1 121 ? 177.653 154.283 93.802  1.00 78.65  ? 121 LEU D CG  1 
ATOM   15084 C CD1 . LEU D 1 121 ? 177.125 154.288 92.375  1.00 78.23  ? 121 LEU D CD1 1 
ATOM   15085 C CD2 . LEU D 1 121 ? 178.854 153.353 93.855  1.00 78.05  ? 121 LEU D CD2 1 
ATOM   15086 N N   . MET D 1 122 ? 175.815 156.175 96.521  1.00 73.09  ? 122 MET D N   1 
ATOM   15087 C CA  . MET D 1 122 ? 174.668 155.802 97.355  1.00 73.38  ? 122 MET D CA  1 
ATOM   15088 C C   . MET D 1 122 ? 173.464 156.703 97.072  1.00 75.13  ? 122 MET D C   1 
ATOM   15089 O O   . MET D 1 122 ? 172.347 156.213 96.912  1.00 72.75  ? 122 MET D O   1 
ATOM   15090 C CB  . MET D 1 122 ? 175.031 155.883 98.836  1.00 72.11  ? 122 MET D CB  1 
ATOM   15091 C CG  . MET D 1 122 ? 176.140 154.913 99.220  1.00 70.76  ? 122 MET D CG  1 
ATOM   15092 S SD  . MET D 1 122 ? 176.578 155.042 100.961 1.00 76.71  ? 122 MET D SD  1 
ATOM   15093 C CE  . MET D 1 122 ? 178.232 154.338 100.907 1.00 71.77  ? 122 MET D CE  1 
ATOM   15094 N N   . LYS D 1 123 ? 173.687 158.016 96.937  1.00 82.09  ? 123 LYS D N   1 
ATOM   15095 C CA  . LYS D 1 123 ? 172.623 158.970 96.592  1.00 80.91  ? 123 LYS D CA  1 
ATOM   15096 C C   . LYS D 1 123 ? 172.099 158.816 95.151  1.00 79.18  ? 123 LYS D C   1 
ATOM   15097 O O   . LYS D 1 123 ? 170.964 159.196 94.896  1.00 79.42  ? 123 LYS D O   1 
ATOM   15098 C CB  . LYS D 1 123 ? 173.094 160.394 96.940  1.00 81.91  ? 123 LYS D CB  1 
ATOM   15099 C CG  . LYS D 1 123 ? 171.915 161.324 97.249  1.00 82.47  ? 123 LYS D CG  1 
ATOM   15100 C CD  . LYS D 1 123 ? 172.342 162.584 98.007  1.00 82.52  ? 123 LYS D CD  1 
ATOM   15101 C CE  . LYS D 1 123 ? 171.101 163.376 98.433  1.00 82.96  ? 123 LYS D CE  1 
ATOM   15102 N NZ  . LYS D 1 123 ? 171.410 164.472 99.382  1.00 83.82  ? 123 LYS D NZ  1 
ATOM   15103 N N   . ALA D 1 124 ? 172.875 158.225 94.243  1.00 79.04  ? 124 ALA D N   1 
ATOM   15104 C CA  . ALA D 1 124 ? 172.450 157.820 92.899  1.00 79.68  ? 124 ALA D CA  1 
ATOM   15105 C C   . ALA D 1 124 ? 171.604 156.529 92.906  1.00 79.53  ? 124 ALA D C   1 
ATOM   15106 O O   . ALA D 1 124 ? 170.667 156.399 92.122  1.00 80.54  ? 124 ALA D O   1 
ATOM   15107 C CB  . ALA D 1 124 ? 173.697 157.613 92.030  1.00 78.54  ? 124 ALA D CB  1 
ATOM   15108 N N   . VAL D 1 125 ? 171.944 155.559 93.764  1.00 74.40  ? 125 VAL D N   1 
ATOM   15109 C CA  . VAL D 1 125 ? 171.204 154.295 93.917  1.00 72.94  ? 125 VAL D CA  1 
ATOM   15110 C C   . VAL D 1 125 ? 169.876 154.507 94.662  1.00 73.58  ? 125 VAL D C   1 
ATOM   15111 O O   . VAL D 1 125 ? 168.899 153.810 94.404  1.00 73.37  ? 125 VAL D O   1 
ATOM   15112 C CB  . VAL D 1 125 ? 172.095 153.237 94.598  1.00 70.50  ? 125 VAL D CB  1 
ATOM   15113 C CG1 . VAL D 1 125 ? 171.355 151.935 94.875  1.00 69.26  ? 125 VAL D CG1 1 
ATOM   15114 C CG2 . VAL D 1 125 ? 173.286 152.860 93.711  1.00 71.38  ? 125 VAL D CG2 1 
ATOM   15115 N N   . LEU D 1 126 ? 169.784 155.502 95.545  1.00 71.90  ? 126 LEU D N   1 
ATOM   15116 C CA  . LEU D 1 126 ? 168.495 156.024 96.017  1.00 71.31  ? 126 LEU D CA  1 
ATOM   15117 C C   . LEU D 1 126 ? 167.739 156.749 94.883  1.00 74.39  ? 126 LEU D C   1 
ATOM   15118 O O   . LEU D 1 126 ? 168.339 157.360 94.008  1.00 77.05  ? 126 LEU D O   1 
ATOM   15119 C CB  . LEU D 1 126 ? 168.732 156.938 97.228  1.00 71.57  ? 126 LEU D CB  1 
ATOM   15120 C CG  . LEU D 1 126 ? 169.307 156.193 98.446  1.00 69.04  ? 126 LEU D CG  1 
ATOM   15121 C CD1 . LEU D 1 126 ? 169.817 157.176 99.487  1.00 67.47  ? 126 LEU D CD1 1 
ATOM   15122 C CD2 . LEU D 1 126 ? 168.257 155.299 99.092  1.00 68.13  ? 126 LEU D CD2 1 
ATOM   15123 N N   . ASN D 1 127 ? 166.401 156.685 94.897  1.00 81.78  ? 127 ASN D N   1 
ATOM   15124 C CA  . ASN D 1 127 ? 165.556 157.330 93.849  1.00 84.68  ? 127 ASN D CA  1 
ATOM   15125 C C   . ASN D 1 127 ? 165.961 156.815 92.460  1.00 83.67  ? 127 ASN D C   1 
ATOM   15126 O O   . ASN D 1 127 ? 166.639 157.560 91.725  1.00 81.53  ? 127 ASN D O   1 
ATOM   15127 C CB  . ASN D 1 127 ? 165.514 158.863 93.967  1.00 84.29  ? 127 ASN D CB  1 
ATOM   15128 C CG  . ASN D 1 127 ? 166.863 159.549 93.900  1.00 84.06  ? 127 ASN D CG  1 
ATOM   15129 O OD1 . ASN D 1 127 ? 167.325 159.921 92.824  1.00 84.79  ? 127 ASN D OD1 1 
ATOM   15130 N ND2 . ASN D 1 127 ? 167.495 159.734 95.047  1.00 82.51  ? 127 ASN D ND2 1 
ATOM   15131 N N   . LEU D 1 128 ? 165.555 155.587 92.119  1.00 88.67  ? 128 LEU D N   1 
ATOM   15132 C CA  . LEU D 1 128 ? 165.834 155.035 90.764  1.00 86.50  ? 128 LEU D CA  1 
ATOM   15133 C C   . LEU D 1 128 ? 164.571 155.183 89.911  1.00 88.71  ? 128 LEU D C   1 
ATOM   15134 O O   . LEU D 1 128 ? 163.476 154.886 90.428  1.00 88.00  ? 128 LEU D O   1 
ATOM   15135 C CB  . LEU D 1 128 ? 166.240 153.564 90.890  1.00 88.40  ? 128 LEU D CB  1 
ATOM   15136 C CG  . LEU D 1 128 ? 167.533 153.303 91.660  1.00 87.99  ? 128 LEU D CG  1 
ATOM   15137 C CD1 . LEU D 1 128 ? 167.851 151.816 91.696  1.00 86.78  ? 128 LEU D CD1 1 
ATOM   15138 C CD2 . LEU D 1 128 ? 168.690 154.078 91.049  1.00 86.79  ? 128 LEU D CD2 1 
ATOM   15139 N N   . GLN D 1 129 ? 164.718 155.622 88.658  1.00 99.13  ? 129 GLN D N   1 
ATOM   15140 C CA  . GLN D 1 129 ? 163.556 155.848 87.792  1.00 98.53  ? 129 GLN D CA  1 
ATOM   15141 C C   . GLN D 1 129 ? 163.285 154.593 86.951  1.00 98.99  ? 129 GLN D C   1 
ATOM   15142 O O   . GLN D 1 129 ? 164.180 154.096 86.269  1.00 99.43  ? 129 GLN D O   1 
ATOM   15143 C CB  . GLN D 1 129 ? 163.804 157.076 86.899  1.00 98.10  ? 129 GLN D CB  1 
ATOM   15144 C CG  . GLN D 1 129 ? 164.073 158.362 87.700  1.00 97.97  ? 129 GLN D CG  1 
ATOM   15145 C CD  . GLN D 1 129 ? 164.205 159.611 86.831  1.00 100.35 ? 129 GLN D CD  1 
ATOM   15146 O OE1 . GLN D 1 129 ? 164.138 159.588 85.610  1.00 99.99  ? 129 GLN D OE1 1 
ATOM   15147 N NE2 . GLN D 1 129 ? 164.395 160.763 87.430  1.00 99.45  ? 129 GLN D NE2 1 
ATOM   15148 N N   . ASP D 1 130 ? 162.085 154.010 87.024  1.00 98.50  ? 130 ASP D N   1 
ATOM   15149 C CA  . ASP D 1 130 ? 161.761 152.735 86.359  1.00 99.35  ? 130 ASP D CA  1 
ATOM   15150 C C   . ASP D 1 130 ? 162.749 151.581 86.651  1.00 98.79  ? 130 ASP D C   1 
ATOM   15151 O O   . ASP D 1 130 ? 162.971 150.698 85.819  1.00 98.45  ? 130 ASP D O   1 
ATOM   15152 C CB  . ASP D 1 130 ? 161.567 152.974 84.862  1.00 98.90  ? 130 ASP D CB  1 
ATOM   15153 N N   . GLY D 1 131 ? 163.376 151.596 87.833  1.00 92.19  ? 131 GLY D N   1 
ATOM   15154 C CA  . GLY D 1 131 ? 164.360 150.609 88.280  1.00 92.49  ? 131 GLY D CA  1 
ATOM   15155 C C   . GLY D 1 131 ? 165.824 150.881 87.903  1.00 92.69  ? 131 GLY D C   1 
ATOM   15156 O O   . GLY D 1 131 ? 166.674 150.056 88.230  1.00 92.12  ? 131 GLY D O   1 
ATOM   15157 N N   . VAL D 1 132 ? 166.155 152.009 87.261  1.00 93.37  ? 132 VAL D N   1 
ATOM   15158 C CA  . VAL D 1 132 ? 167.530 152.348 86.831  1.00 94.39  ? 132 VAL D CA  1 
ATOM   15159 C C   . VAL D 1 132 ? 167.868 153.836 87.037  1.00 93.30  ? 132 VAL D C   1 
ATOM   15160 O O   . VAL D 1 132 ? 166.989 154.672 87.216  1.00 92.56  ? 132 VAL D O   1 
ATOM   15161 C CB  . VAL D 1 132 ? 167.741 151.862 85.381  1.00 95.87  ? 132 VAL D CB  1 
ATOM   15162 C CG1 . VAL D 1 132 ? 166.968 152.686 84.352  1.00 94.85  ? 132 VAL D CG1 1 
ATOM   15163 C CG2 . VAL D 1 132 ? 169.216 151.809 84.971  1.00 93.64  ? 132 VAL D CG2 1 
ATOM   15164 N N   . ASN D 1 133 ? 169.155 154.184 87.035  1.00 94.06  ? 133 ASN D N   1 
ATOM   15165 C CA  . ASN D 1 133 ? 169.621 155.571 87.038  1.00 94.69  ? 133 ASN D CA  1 
ATOM   15166 C C   . ASN D 1 133 ? 170.814 155.725 86.080  1.00 94.20  ? 133 ASN D C   1 
ATOM   15167 O O   . ASN D 1 133 ? 171.887 155.158 86.308  1.00 94.08  ? 133 ASN D O   1 
ATOM   15168 C CB  . ASN D 1 133 ? 169.937 155.989 88.485  1.00 94.48  ? 133 ASN D CB  1 
ATOM   15169 C CG  . ASN D 1 133 ? 170.431 157.417 88.622  1.00 93.51  ? 133 ASN D CG  1 
ATOM   15170 O OD1 . ASN D 1 133 ? 170.825 158.069 87.669  1.00 95.02  ? 133 ASN D OD1 1 
ATOM   15171 N ND2 . ASN D 1 133 ? 170.420 157.948 89.812  1.00 92.72  ? 133 ASN D ND2 1 
ATOM   15172 N N   . ALA D 1 134 ? 170.634 156.517 85.023  1.00 96.21  ? 134 ALA D N   1 
ATOM   15173 C CA  . ALA D 1 134 ? 171.633 156.736 83.974  1.00 96.93  ? 134 ALA D CA  1 
ATOM   15174 C C   . ALA D 1 134 ? 172.949 157.368 84.466  1.00 97.70  ? 134 ALA D C   1 
ATOM   15175 O O   . ALA D 1 134 ? 173.963 157.274 83.780  1.00 98.40  ? 134 ALA D O   1 
ATOM   15176 C CB  . ALA D 1 134 ? 170.987 157.605 82.890  1.00 97.40  ? 134 ALA D CB  1 
ATOM   15177 N N   . CYS D 1 135 ? 172.962 157.986 85.649  1.00 97.37  ? 135 CYS D N   1 
ATOM   15178 C CA  . CYS D 1 135 ? 174.146 158.601 86.248  1.00 97.56  ? 135 CYS D CA  1 
ATOM   15179 C C   . CYS D 1 135 ? 175.130 157.593 86.884  1.00 99.00  ? 135 CYS D C   1 
ATOM   15180 O O   . CYS D 1 135 ? 176.314 157.894 87.013  1.00 98.08  ? 135 CYS D O   1 
ATOM   15181 C CB  . CYS D 1 135 ? 173.637 159.641 87.252  1.00 98.69  ? 135 CYS D CB  1 
ATOM   15182 S SG  . CYS D 1 135 ? 174.982 160.697 87.832  1.00 103.17 ? 135 CYS D SG  1 
ATOM   15183 N N   . ILE D 1 136 ? 174.692 156.374 87.242  1.00 96.04  ? 136 ILE D N   1 
ATOM   15184 C CA  . ILE D 1 136 ? 175.536 155.418 87.989  1.00 94.57  ? 136 ILE D CA  1 
ATOM   15185 C C   . ILE D 1 136 ? 176.782 154.996 87.190  1.00 94.76  ? 136 ILE D C   1 
ATOM   15186 O O   . ILE D 1 136 ? 177.898 155.077 87.707  1.00 94.69  ? 136 ILE D O   1 
ATOM   15187 C CB  . ILE D 1 136 ? 174.703 154.212 88.486  1.00 94.45  ? 136 ILE D CB  1 
ATOM   15188 C CG1 . ILE D 1 136 ? 173.679 154.680 89.542  1.00 93.41  ? 136 ILE D CG1 1 
ATOM   15189 C CG2 . ILE D 1 136 ? 175.614 153.138 89.100  1.00 94.90  ? 136 ILE D CG2 1 
ATOM   15190 C CD1 . ILE D 1 136 ? 172.661 153.611 89.954  1.00 92.27  ? 136 ILE D CD1 1 
ATOM   15191 N N   . MET D 1 137 ? 176.634 154.589 85.922  1.00 98.27  ? 137 MET D N   1 
ATOM   15192 C CA  . MET D 1 137 ? 177.791 154.254 85.078  1.00 98.89  ? 137 MET D CA  1 
ATOM   15193 C C   . MET D 1 137 ? 178.772 155.437 84.915  1.00 99.81  ? 137 MET D C   1 
ATOM   15194 O O   . MET D 1 137 ? 179.946 155.247 85.218  1.00 98.91  ? 137 MET D O   1 
ATOM   15195 C CB  . MET D 1 137 ? 177.362 153.674 83.720  1.00 98.90  ? 137 MET D CB  1 
ATOM   15196 C CG  . MET D 1 137 ? 176.855 152.240 83.804  1.00 99.18  ? 137 MET D CG  1 
ATOM   15197 S SD  . MET D 1 137 ? 176.445 151.550 82.180  1.00 103.27 ? 137 MET D SD  1 
ATOM   15198 C CE  . MET D 1 137 ? 175.823 149.921 82.650  1.00 98.88  ? 137 MET D CE  1 
ATOM   15199 N N   . PRO D 1 138 ? 178.345 156.659 84.531  1.00 100.30 ? 138 PRO D N   1 
ATOM   15200 C CA  . PRO D 1 138 ? 179.183 157.858 84.555  1.00 99.91  ? 138 PRO D CA  1 
ATOM   15201 C C   . PRO D 1 138 ? 179.946 158.106 85.861  1.00 100.71 ? 138 PRO D C   1 
ATOM   15202 O O   . PRO D 1 138 ? 181.140 158.395 85.804  1.00 100.65 ? 138 PRO D O   1 
ATOM   15203 C CB  . PRO D 1 138 ? 178.234 159.018 84.259  1.00 101.14 ? 138 PRO D CB  1 
ATOM   15204 C CG  . PRO D 1 138 ? 177.201 158.385 83.342  1.00 100.45 ? 138 PRO D CG  1 
ATOM   15205 C CD  . PRO D 1 138 ? 177.088 156.961 83.868  1.00 99.80  ? 138 PRO D CD  1 
ATOM   15206 N N   . LEU D 1 139 ? 179.327 157.953 87.039  1.00 98.66  ? 139 LEU D N   1 
ATOM   15207 C CA  . LEU D 1 139 ? 180.034 158.088 88.326  1.00 98.69  ? 139 LEU D CA  1 
ATOM   15208 C C   . LEU D 1 139 ? 181.156 157.054 88.477  1.00 99.71  ? 139 LEU D C   1 
ATOM   15209 O O   . LEU D 1 139 ? 182.271 157.399 88.860  1.00 99.21  ? 139 LEU D O   1 
ATOM   15210 C CB  . LEU D 1 139 ? 179.057 157.916 89.501  1.00 99.01  ? 139 LEU D CB  1 
ATOM   15211 C CG  . LEU D 1 139 ? 178.040 159.049 89.677  1.00 99.85  ? 139 LEU D CG  1 
ATOM   15212 C CD1 . LEU D 1 139 ? 176.958 158.584 90.648  1.00 99.03  ? 139 LEU D CD1 1 
ATOM   15213 C CD2 . LEU D 1 139 ? 178.705 160.305 90.248  1.00 100.37 ? 139 LEU D CD2 1 
ATOM   15214 N N   . LEU D 1 140 ? 180.877 155.786 88.162  1.00 98.12  ? 140 LEU D N   1 
ATOM   15215 C CA  . LEU D 1 140 ? 181.858 154.701 88.233  1.00 98.40  ? 140 LEU D CA  1 
ATOM   15216 C C   . LEU D 1 140 ? 182.974 154.870 87.187  1.00 97.90  ? 140 LEU D C   1 
ATOM   15217 O O   . LEU D 1 140 ? 184.138 154.606 87.475  1.00 97.83  ? 140 LEU D O   1 
ATOM   15218 C CB  . LEU D 1 140 ? 181.124 153.357 88.073  1.00 97.32  ? 140 LEU D CB  1 
ATOM   15219 C CG  . LEU D 1 140 ? 180.157 153.026 89.231  1.00 96.23  ? 140 LEU D CG  1 
ATOM   15220 C CD1 . LEU D 1 140 ? 179.244 151.868 88.846  1.00 95.62  ? 140 LEU D CD1 1 
ATOM   15221 C CD2 . LEU D 1 140 ? 180.916 152.646 90.495  1.00 95.66  ? 140 LEU D CD2 1 
ATOM   15222 N N   . GLN D 1 141 ? 182.651 155.357 85.986  1.00 101.73 ? 141 GLN D N   1 
ATOM   15223 C CA  . GLN D 1 141 ? 183.624 155.725 84.960  1.00 102.82 ? 141 GLN D CA  1 
ATOM   15224 C C   . GLN D 1 141 ? 184.533 156.859 85.449  1.00 102.24 ? 141 GLN D C   1 
ATOM   15225 O O   . GLN D 1 141 ? 185.749 156.711 85.420  1.00 102.65 ? 141 GLN D O   1 
ATOM   15226 C CB  . GLN D 1 141 ? 182.897 156.118 83.666  1.00 102.16 ? 141 GLN D CB  1 
ATOM   15227 C CG  . GLN D 1 141 ? 182.264 154.905 82.964  1.00 102.59 ? 141 GLN D CG  1 
ATOM   15228 C CD  . GLN D 1 141 ? 181.234 155.275 81.897  1.00 102.54 ? 141 GLN D CD  1 
ATOM   15229 O OE1 . GLN D 1 141 ? 180.997 156.427 81.561  1.00 101.91 ? 141 GLN D OE1 1 
ATOM   15230 N NE2 . GLN D 1 141 ? 180.581 154.299 81.306  1.00 101.78 ? 141 GLN D NE2 1 
ATOM   15231 N N   . ILE D 1 142 ? 183.971 157.954 85.970  1.00 103.52 ? 142 ILE D N   1 
ATOM   15232 C CA  . ILE D 1 142 ? 184.743 159.077 86.525  1.00 104.66 ? 142 ILE D CA  1 
ATOM   15233 C C   . ILE D 1 142 ? 185.621 158.619 87.698  1.00 104.15 ? 142 ILE D C   1 
ATOM   15234 O O   . ILE D 1 142 ? 186.756 159.070 87.826  1.00 103.82 ? 142 ILE D O   1 
ATOM   15235 C CB  . ILE D 1 142 ? 183.789 160.232 86.914  1.00 104.24 ? 142 ILE D CB  1 
ATOM   15236 C CG1 . ILE D 1 142 ? 183.233 160.883 85.628  1.00 104.41 ? 142 ILE D CG1 1 
ATOM   15237 C CG2 . ILE D 1 142 ? 184.467 161.295 87.792  1.00 103.86 ? 142 ILE D CG2 1 
ATOM   15238 C CD1 . ILE D 1 142 ? 182.066 161.837 85.863  1.00 104.64 ? 142 ILE D CD1 1 
ATOM   15239 N N   . ASP D 1 143 ? 185.151 157.716 88.559  1.00 103.46 ? 143 ASP D N   1 
ATOM   15240 C CA  . ASP D 1 143 ? 185.957 157.198 89.669  1.00 102.99 ? 143 ASP D CA  1 
ATOM   15241 C C   . ASP D 1 143 ? 187.160 156.360 89.188  1.00 103.96 ? 143 ASP D C   1 
ATOM   15242 O O   . ASP D 1 143 ? 188.288 156.569 89.636  1.00 103.29 ? 143 ASP D O   1 
ATOM   15243 C CB  . ASP D 1 143 ? 185.071 156.374 90.608  1.00 102.31 ? 143 ASP D CB  1 
ATOM   15244 C CG  . ASP D 1 143 ? 185.823 156.036 91.897  1.00 103.79 ? 143 ASP D CG  1 
ATOM   15245 O OD1 . ASP D 1 143 ? 186.337 156.974 92.544  1.00 103.82 ? 143 ASP D OD1 1 
ATOM   15246 O OD2 . ASP D 1 143 ? 185.872 154.844 92.265  1.00 103.77 ? 143 ASP D OD2 1 
ATOM   15247 N N   . LYS D 1 144 ? 186.941 155.454 88.224  1.00 105.63 ? 144 LYS D N   1 
ATOM   15248 C CA  . LYS D 1 144 ? 188.012 154.660 87.586  1.00 104.84 ? 144 LYS D CA  1 
ATOM   15249 C C   . LYS D 1 144 ? 188.994 155.544 86.811  1.00 104.99 ? 144 LYS D C   1 
ATOM   15250 O O   . LYS D 1 144 ? 190.205 155.389 86.949  1.00 104.31 ? 144 LYS D O   1 
ATOM   15251 C CB  . LYS D 1 144 ? 187.392 153.585 86.674  1.00 104.36 ? 144 LYS D CB  1 
ATOM   15252 C CG  . LYS D 1 144 ? 186.712 152.469 87.482  1.00 105.16 ? 144 LYS D CG  1 
ATOM   15253 C CD  . LYS D 1 144 ? 186.055 151.379 86.621  1.00 104.04 ? 144 LYS D CD  1 
ATOM   15254 C CE  . LYS D 1 144 ? 184.925 151.911 85.731  1.00 104.11 ? 144 LYS D CE  1 
ATOM   15255 N NZ  . LYS D 1 144 ? 184.209 150.811 85.032  1.00 103.81 ? 144 LYS D NZ  1 
ATOM   15256 N N   . ASP D 1 145 ? 188.492 156.525 86.060  1.00 109.07 ? 145 ASP D N   1 
ATOM   15257 C CA  . ASP D 1 145 ? 189.298 157.523 85.345  1.00 108.90 ? 145 ASP D CA  1 
ATOM   15258 C C   . ASP D 1 145 ? 190.086 158.459 86.281  1.00 108.59 ? 145 ASP D C   1 
ATOM   15259 O O   . ASP D 1 145 ? 191.133 158.978 85.894  1.00 109.56 ? 145 ASP D O   1 
ATOM   15260 C CB  . ASP D 1 145 ? 188.403 158.351 84.407  1.00 108.84 ? 145 ASP D CB  1 
ATOM   15261 C CG  . ASP D 1 145 ? 187.783 157.563 83.240  1.00 108.99 ? 145 ASP D CG  1 
ATOM   15262 O OD1 . ASP D 1 145 ? 188.256 156.444 82.930  1.00 109.19 ? 145 ASP D OD1 1 
ATOM   15263 O OD2 . ASP D 1 145 ? 186.876 158.105 82.569  1.00 107.95 ? 145 ASP D OD2 1 
ATOM   15264 N N   . SER D 1 146 ? 189.635 158.657 87.520  1.00 109.43 ? 146 SER D N   1 
ATOM   15265 C CA  . SER D 1 146 ? 190.368 159.420 88.543  1.00 110.01 ? 146 SER D CA  1 
ATOM   15266 C C   . SER D 1 146 ? 191.534 158.643 89.173  1.00 109.75 ? 146 SER D C   1 
ATOM   15267 O O   . SER D 1 146 ? 192.378 159.251 89.827  1.00 109.08 ? 146 SER D O   1 
ATOM   15268 C CB  . SER D 1 146 ? 189.422 159.875 89.661  1.00 110.34 ? 146 SER D CB  1 
ATOM   15269 O OG  . SER D 1 146 ? 188.379 160.677 89.154  1.00 111.83 ? 146 SER D OG  1 
ATOM   15270 N N   . GLY D 1 147 ? 191.611 157.317 89.008  1.00 107.54 ? 147 GLY D N   1 
ATOM   15271 C CA  . GLY D 1 147 ? 192.664 156.490 89.614  1.00 107.60 ? 147 GLY D CA  1 
ATOM   15272 C C   . GLY D 1 147 ? 192.543 156.316 91.134  1.00 108.39 ? 147 GLY D C   1 
ATOM   15273 O O   . GLY D 1 147 ? 193.553 156.177 91.826  1.00 108.18 ? 147 GLY D O   1 
ATOM   15274 N N   . ASN D 1 148 ? 191.324 156.362 91.677  1.00 107.57 ? 148 ASN D N   1 
ATOM   15275 C CA  . ASN D 1 148 ? 191.100 156.312 93.149  1.00 107.49 ? 148 ASN D CA  1 
ATOM   15276 C C   . ASN D 1 148 ? 191.479 154.940 93.711  1.00 107.05 ? 148 ASN D C   1 
ATOM   15277 O O   . ASN D 1 148 ? 190.937 153.930 93.225  1.00 105.15 ? 148 ASN D O   1 
ATOM   15278 C CB  . ASN D 1 148 ? 189.649 156.657 93.494  1.00 107.11 ? 148 ASN D CB  1 
ATOM   15279 C CG  . ASN D 1 148 ? 189.334 156.558 94.972  1.00 106.35 ? 148 ASN D CG  1 
ATOM   15280 O OD1 . ASN D 1 148 ? 190.234 156.531 95.808  1.00 105.86 ? 148 ASN D OD1 1 
ATOM   15281 N ND2 . ASN D 1 148 ? 188.054 156.513 95.304  1.00 105.53 ? 148 ASN D ND2 1 
ATOM   15282 N N   . PRO D 1 149 ? 192.379 154.851 94.719  1.00 107.28 ? 149 PRO D N   1 
ATOM   15283 C CA  . PRO D 1 149 ? 192.700 153.568 95.347  1.00 107.01 ? 149 PRO D CA  1 
ATOM   15284 C C   . PRO D 1 149 ? 191.490 152.996 96.100  1.00 106.96 ? 149 PRO D C   1 
ATOM   15285 O O   . PRO D 1 149 ? 191.320 151.792 96.080  1.00 106.34 ? 149 PRO D O   1 
ATOM   15286 C CB  . PRO D 1 149 ? 193.808 153.907 96.358  1.00 106.71 ? 149 PRO D CB  1 
ATOM   15287 C CG  . PRO D 1 149 ? 194.361 155.231 95.881  1.00 106.63 ? 149 PRO D CG  1 
ATOM   15288 C CD  . PRO D 1 149 ? 193.169 155.950 95.289  1.00 106.23 ? 149 PRO D CD  1 
ATOM   15289 N N   . LYS D 1 150 ? 190.687 153.856 96.736  1.00 105.24 ? 150 LYS D N   1 
ATOM   15290 C CA  . LYS D 1 150 ? 189.566 153.344 97.545  1.00 103.39 ? 150 LYS D CA  1 
ATOM   15291 C C   . LYS D 1 150 ? 188.269 153.480 96.750  1.00 103.07 ? 150 LYS D C   1 
ATOM   15292 O O   . LYS D 1 150 ? 187.511 154.434 96.937  1.00 103.30 ? 150 LYS D O   1 
ATOM   15293 C CB  . LYS D 1 150 ? 189.506 154.091 98.889  1.00 102.20 ? 150 LYS D CB  1 
ATOM   15294 C CG  . LYS D 1 150 ? 190.716 153.799 99.783  1.00 102.41 ? 150 LYS D CG  1 
ATOM   15295 C CD  . LYS D 1 150 ? 190.634 154.579 101.095 1.00 103.25 ? 150 LYS D CD  1 
ATOM   15296 C CE  . LYS D 1 150 ? 191.835 154.271 101.986 1.00 103.31 ? 150 LYS D CE  1 
ATOM   15297 N NZ  . LYS D 1 150 ? 191.827 155.068 103.223 1.00 103.56 ? 150 LYS D NZ  1 
ATOM   15298 N N   . LEU D 1 151 ? 188.052 152.553 95.816  1.00 96.15  ? 151 LEU D N   1 
ATOM   15299 C CA  . LEU D 1 151 ? 187.014 152.650 94.785  1.00 96.38  ? 151 LEU D CA  1 
ATOM   15300 C C   . LEU D 1 151 ? 185.624 152.958 95.364  1.00 94.37  ? 151 LEU D C   1 
ATOM   15301 O O   . LEU D 1 151 ? 185.193 152.361 96.352  1.00 93.23  ? 151 LEU D O   1 
ATOM   15302 C CB  . LEU D 1 151 ? 186.970 151.352 93.955  1.00 95.56  ? 151 LEU D CB  1 
ATOM   15303 C CG  . LEU D 1 151 ? 188.239 151.036 93.148  1.00 96.59  ? 151 LEU D CG  1 
ATOM   15304 C CD1 . LEU D 1 151 ? 188.117 149.650 92.530  1.00 95.10  ? 151 LEU D CD1 1 
ATOM   15305 C CD2 . LEU D 1 151 ? 188.471 152.036 92.018  1.00 96.82  ? 151 LEU D CD2 1 
ATOM   15306 N N   . LEU D 1 152 ? 184.901 153.865 94.708  1.00 87.55  ? 152 LEU D N   1 
ATOM   15307 C CA  . LEU D 1 152 ? 183.604 154.400 95.132  1.00 87.00  ? 152 LEU D CA  1 
ATOM   15308 C C   . LEU D 1 152 ? 182.541 153.310 95.328  1.00 86.63  ? 152 LEU D C   1 
ATOM   15309 O O   . LEU D 1 152 ? 181.704 153.413 96.219  1.00 86.90  ? 152 LEU D O   1 
ATOM   15310 C CB  . LEU D 1 152 ? 183.174 155.422 94.064  1.00 87.73  ? 152 LEU D CB  1 
ATOM   15311 C CG  . LEU D 1 152 ? 181.803 156.082 94.253  1.00 86.20  ? 152 LEU D CG  1 
ATOM   15312 C CD1 . LEU D 1 152 ? 181.762 156.952 95.503  1.00 86.08  ? 152 LEU D CD1 1 
ATOM   15313 C CD2 . LEU D 1 152 ? 181.492 156.937 93.029  1.00 87.20  ? 152 LEU D CD2 1 
ATOM   15314 N N   . VAL D 1 153 ? 182.597 152.237 94.536  1.00 77.36  ? 153 VAL D N   1 
ATOM   15315 C CA  . VAL D 1 153 ? 181.636 151.125 94.581  1.00 76.09  ? 153 VAL D CA  1 
ATOM   15316 C C   . VAL D 1 153 ? 181.630 150.376 95.927  1.00 74.36  ? 153 VAL D C   1 
ATOM   15317 O O   . VAL D 1 153 ? 180.594 149.869 96.343  1.00 73.12  ? 153 VAL D O   1 
ATOM   15318 C CB  . VAL D 1 153 ? 181.876 150.200 93.373  1.00 73.05  ? 153 VAL D CB  1 
ATOM   15319 C CG1 . VAL D 1 153 ? 183.113 149.315 93.519  1.00 74.16  ? 153 VAL D CG1 1 
ATOM   15320 C CG2 . VAL D 1 153 ? 180.658 149.331 93.082  1.00 71.94  ? 153 VAL D CG2 1 
ATOM   15321 N N   . ASN D 1 154 ? 182.760 150.375 96.643  1.00 72.56  ? 154 ASN D N   1 
ATOM   15322 C CA  . ASN D 1 154 ? 182.939 149.724 97.944  1.00 71.99  ? 154 ASN D CA  1 
ATOM   15323 C C   . ASN D 1 154 ? 183.048 150.719 99.111  1.00 73.30  ? 154 ASN D C   1 
ATOM   15324 O O   . ASN D 1 154 ? 183.384 150.326 100.230 1.00 73.55  ? 154 ASN D O   1 
ATOM   15325 C CB  . ASN D 1 154 ? 184.136 148.758 97.866  1.00 72.62  ? 154 ASN D CB  1 
ATOM   15326 C CG  . ASN D 1 154 ? 183.870 147.628 96.897  1.00 73.60  ? 154 ASN D CG  1 
ATOM   15327 O OD1 . ASN D 1 154 ? 182.765 147.132 96.814  1.00 74.96  ? 154 ASN D OD1 1 
ATOM   15328 N ND2 . ASN D 1 154 ? 184.831 147.200 96.119  1.00 73.67  ? 154 ASN D ND2 1 
ATOM   15329 N N   . ALA D 1 155 ? 182.764 152.000 98.878  1.00 70.02  ? 155 ALA D N   1 
ATOM   15330 C CA  . ALA D 1 155 ? 182.622 152.971 99.956  1.00 67.45  ? 155 ALA D CA  1 
ATOM   15331 C C   . ALA D 1 155 ? 181.435 152.588 100.855 1.00 68.85  ? 155 ALA D C   1 
ATOM   15332 O O   . ALA D 1 155 ? 180.420 152.069 100.386 1.00 67.66  ? 155 ALA D O   1 
ATOM   15333 C CB  . ALA D 1 155 ? 182.474 154.376 99.368  1.00 70.06  ? 155 ALA D CB  1 
ATOM   15334 N N   . GLN D 1 156 ? 181.566 152.845 102.152 1.00 63.39  ? 156 GLN D N   1 
ATOM   15335 C CA  . GLN D 1 156 ? 180.561 152.491 103.153 1.00 59.38  ? 156 GLN D CA  1 
ATOM   15336 C C   . GLN D 1 156 ? 180.304 153.656 104.109 1.00 62.55  ? 156 GLN D C   1 
ATOM   15337 O O   . GLN D 1 156 ? 181.196 154.477 104.331 1.00 65.46  ? 156 GLN D O   1 
ATOM   15338 C CB  . GLN D 1 156 ? 181.000 151.251 103.924 1.00 58.11  ? 156 GLN D CB  1 
ATOM   15339 C CG  . GLN D 1 156 ? 180.909 149.955 103.137 1.00 60.23  ? 156 GLN D CG  1 
ATOM   15340 C CD  . GLN D 1 156 ? 181.527 148.830 103.926 1.00 61.86  ? 156 GLN D CD  1 
ATOM   15341 O OE1 . GLN D 1 156 ? 182.650 148.933 104.411 1.00 60.25  ? 156 GLN D OE1 1 
ATOM   15342 N NE2 . GLN D 1 156 ? 180.784 147.748 104.081 1.00 60.86  ? 156 GLN D NE2 1 
ATOM   15343 N N   . CYS D 1 157 ? 179.125 153.704 104.723 1.00 60.25  ? 157 CYS D N   1 
ATOM   15344 C CA  . CYS D 1 157 ? 178.846 154.591 105.856 1.00 60.53  ? 157 CYS D CA  1 
ATOM   15345 C C   . CYS D 1 157 ? 179.744 154.260 107.069 1.00 63.97  ? 157 CYS D C   1 
ATOM   15346 O O   . CYS D 1 157 ? 180.195 153.123 107.234 1.00 65.44  ? 157 CYS D O   1 
ATOM   15347 C CB  . CYS D 1 157 ? 177.363 154.521 106.218 1.00 59.44  ? 157 CYS D CB  1 
ATOM   15348 S SG  . CYS D 1 157 ? 176.328 155.084 104.841 1.00 66.27  ? 157 CYS D SG  1 
ATOM   15349 N N   . THR D 1 158 ? 179.991 155.247 107.931 1.00 64.48  ? 158 THR D N   1 
ATOM   15350 C CA  . THR D 1 158 ? 181.078 155.230 108.932 1.00 63.84  ? 158 THR D CA  1 
ATOM   15351 C C   . THR D 1 158 ? 180.605 155.523 110.363 1.00 63.94  ? 158 THR D C   1 
ATOM   15352 O O   . THR D 1 158 ? 181.312 155.221 111.320 1.00 64.53  ? 158 THR D O   1 
ATOM   15353 C CB  . THR D 1 158 ? 182.160 156.246 108.512 1.00 63.89  ? 158 THR D CB  1 
ATOM   15354 O OG1 . THR D 1 158 ? 182.593 155.981 107.196 1.00 63.58  ? 158 THR D OG1 1 
ATOM   15355 C CG2 . THR D 1 158 ? 183.421 156.240 109.375 1.00 63.35  ? 158 THR D CG2 1 
ATOM   15356 N N   . ASP D 1 159 ? 179.415 156.095 110.550 1.00 59.73  ? 159 ASP D N   1 
ATOM   15357 C CA  . ASP D 1 159 ? 178.873 156.426 111.877 1.00 61.46  ? 159 ASP D CA  1 
ATOM   15358 C C   . ASP D 1 159 ? 178.429 155.194 112.685 1.00 60.26  ? 159 ASP D C   1 
ATOM   15359 O O   . ASP D 1 159 ? 178.222 154.113 112.145 1.00 63.11  ? 159 ASP D O   1 
ATOM   15360 C CB  . ASP D 1 159 ? 177.689 157.373 111.722 1.00 64.05  ? 159 ASP D CB  1 
ATOM   15361 C CG  . ASP D 1 159 ? 176.502 156.653 111.085 1.00 63.66  ? 159 ASP D CG  1 
ATOM   15362 O OD1 . ASP D 1 159 ? 176.495 156.512 109.845 1.00 62.13  ? 159 ASP D OD1 1 
ATOM   15363 O OD2 . ASP D 1 159 ? 175.623 156.214 111.856 1.00 61.39  ? 159 ASP D OD2 1 
ATOM   15364 N N   . GLU D 1 160 ? 178.212 155.364 113.991 1.00 58.47  ? 160 GLU D N   1 
ATOM   15365 C CA  . GLU D 1 160 ? 177.851 154.278 114.905 1.00 58.11  ? 160 GLU D CA  1 
ATOM   15366 C C   . GLU D 1 160 ? 176.565 153.518 114.525 1.00 60.35  ? 160 GLU D C   1 
ATOM   15367 O O   . GLU D 1 160 ? 176.470 152.322 114.793 1.00 60.48  ? 160 GLU D O   1 
ATOM   15368 C CB  . GLU D 1 160 ? 177.751 154.867 116.324 1.00 58.56  ? 160 GLU D CB  1 
ATOM   15369 C CG  . GLU D 1 160 ? 177.377 153.845 117.404 1.00 60.84  ? 160 GLU D CG  1 
ATOM   15370 C CD  . GLU D 1 160 ? 177.551 154.359 118.844 1.00 64.73  ? 160 GLU D CD  1 
ATOM   15371 O OE1 . GLU D 1 160 ? 177.721 155.575 119.071 1.00 62.53  ? 160 GLU D OE1 1 
ATOM   15372 O OE2 . GLU D 1 160 ? 177.506 153.535 119.773 1.00 64.50  ? 160 GLU D OE2 1 
ATOM   15373 N N   . PHE D 1 161 ? 175.573 154.160 113.900 1.00 52.76  ? 161 PHE D N   1 
ATOM   15374 C CA  . PHE D 1 161 ? 174.317 153.499 113.541 1.00 48.94  ? 161 PHE D CA  1 
ATOM   15375 C C   . PHE D 1 161 ? 174.382 152.799 112.193 1.00 50.48  ? 161 PHE D C   1 
ATOM   15376 O O   . PHE D 1 161 ? 173.919 151.661 112.106 1.00 52.55  ? 161 PHE D O   1 
ATOM   15377 C CB  . PHE D 1 161 ? 173.131 154.461 113.627 1.00 45.27  ? 161 PHE D CB  1 
ATOM   15378 C CG  . PHE D 1 161 ? 172.566 154.496 115.028 1.00 51.87  ? 161 PHE D CG  1 
ATOM   15379 C CD1 . PHE D 1 161 ? 173.201 155.244 116.034 1.00 53.50  ? 161 PHE D CD1 1 
ATOM   15380 C CD2 . PHE D 1 161 ? 171.457 153.694 115.348 1.00 51.46  ? 161 PHE D CD2 1 
ATOM   15381 C CE1 . PHE D 1 161 ? 172.727 155.188 117.355 1.00 54.39  ? 161 PHE D CE1 1 
ATOM   15382 C CE2 . PHE D 1 161 ? 170.983 153.637 116.666 1.00 53.28  ? 161 PHE D CE2 1 
ATOM   15383 C CZ  . PHE D 1 161 ? 171.621 154.385 117.672 1.00 55.25  ? 161 PHE D CZ  1 
ATOM   15384 N N   . TYR D 1 162 ? 174.976 153.410 111.170 1.00 46.24  ? 162 TYR D N   1 
ATOM   15385 C CA  . TYR D 1 162 ? 174.964 152.855 109.816 1.00 42.24  ? 162 TYR D CA  1 
ATOM   15386 C C   . TYR D 1 162 ? 176.305 152.277 109.338 1.00 49.28  ? 162 TYR D C   1 
ATOM   15387 O O   . TYR D 1 162 ? 176.440 151.979 108.157 1.00 49.20  ? 162 TYR D O   1 
ATOM   15388 C CB  . TYR D 1 162 ? 174.315 153.833 108.830 1.00 46.28  ? 162 TYR D CB  1 
ATOM   15389 C CG  . TYR D 1 162 ? 172.987 154.375 109.322 1.00 48.50  ? 162 TYR D CG  1 
ATOM   15390 C CD1 . TYR D 1 162 ? 171.862 153.527 109.376 1.00 47.06  ? 162 TYR D CD1 1 
ATOM   15391 C CD2 . TYR D 1 162 ? 172.892 155.689 109.802 1.00 49.83  ? 162 TYR D CD2 1 
ATOM   15392 C CE1 . TYR D 1 162 ? 170.657 153.994 109.919 1.00 45.25  ? 162 TYR D CE1 1 
ATOM   15393 C CE2 . TYR D 1 162 ? 171.683 156.161 110.350 1.00 45.66  ? 162 TYR D CE2 1 
ATOM   15394 C CZ  . TYR D 1 162 ? 170.569 155.306 110.414 1.00 44.97  ? 162 TYR D CZ  1 
ATOM   15395 O OH  . TYR D 1 162 ? 169.413 155.743 110.967 1.00 50.00  ? 162 TYR D OH  1 
ATOM   15396 N N   . GLN D 1 163 ? 177.288 152.063 110.224 1.00 51.48  ? 163 GLN D N   1 
ATOM   15397 C CA  . GLN D 1 163 ? 178.612 151.538 109.866 1.00 51.99  ? 163 GLN D CA  1 
ATOM   15398 C C   . GLN D 1 163 ? 178.557 150.335 108.908 1.00 52.81  ? 163 GLN D C   1 
ATOM   15399 O O   . GLN D 1 163 ? 177.868 149.347 109.159 1.00 55.12  ? 163 GLN D O   1 
ATOM   15400 C CB  . GLN D 1 163 ? 179.399 151.168 111.132 1.00 52.23  ? 163 GLN D CB  1 
ATOM   15401 C CG  . GLN D 1 163 ? 180.863 150.827 110.823 1.00 54.51  ? 163 GLN D CG  1 
ATOM   15402 C CD  . GLN D 1 163 ? 181.727 150.711 112.072 1.00 57.59  ? 163 GLN D CD  1 
ATOM   15403 O OE1 . GLN D 1 163 ? 181.260 150.557 113.190 1.00 55.68  ? 163 GLN D OE1 1 
ATOM   15404 N NE2 . GLN D 1 163 ? 183.028 150.776 111.932 1.00 56.54  ? 163 GLN D NE2 1 
ATOM   15405 N N   . GLY D 1 164 ? 179.309 150.409 107.814 1.00 52.46  ? 164 GLY D N   1 
ATOM   15406 C CA  . GLY D 1 164 ? 179.439 149.325 106.844 1.00 48.54  ? 164 GLY D CA  1 
ATOM   15407 C C   . GLY D 1 164 ? 178.315 149.224 105.810 1.00 47.22  ? 164 GLY D C   1 
ATOM   15408 O O   . GLY D 1 164 ? 178.412 148.413 104.892 1.00 54.57  ? 164 GLY D O   1 
ATOM   15409 N N   . HIS D 1 165 ? 177.339 150.122 105.884 1.00 44.24  ? 165 HIS D N   1 
ATOM   15410 C CA  . HIS D 1 165 ? 176.244 150.178 104.881 1.00 42.67  ? 165 HIS D CA  1 
ATOM   15411 C C   . HIS D 1 165 ? 176.847 150.592 103.550 1.00 48.32  ? 165 HIS D C   1 
ATOM   15412 O O   . HIS D 1 165 ? 177.771 151.382 103.577 1.00 54.20  ? 165 HIS D O   1 
ATOM   15413 C CB  . HIS D 1 165 ? 175.143 151.121 105.349 1.00 48.71  ? 165 HIS D CB  1 
ATOM   15414 C CG  . HIS D 1 165 ? 173.889 151.100 104.548 1.00 48.72  ? 165 HIS D CG  1 
ATOM   15415 N ND1 . HIS D 1 165 ? 173.367 149.945 104.027 1.00 50.04  ? 165 HIS D ND1 1 
ATOM   15416 C CD2 . HIS D 1 165 ? 173.040 152.087 104.206 1.00 47.28  ? 165 HIS D CD2 1 
ATOM   15417 C CE1 . HIS D 1 165 ? 172.256 150.222 103.384 1.00 49.19  ? 165 HIS D CE1 1 
ATOM   15418 N NE2 . HIS D 1 165 ? 172.031 151.525 103.481 1.00 45.32  ? 165 HIS D NE2 1 
ATOM   15419 N N   . SER D 1 166 ? 176.306 150.119 102.433 1.00 47.04  ? 166 SER D N   1 
ATOM   15420 C CA  . SER D 1 166 ? 176.940 150.319 101.123 1.00 46.49  ? 166 SER D CA  1 
ATOM   15421 C C   . SER D 1 166 ? 175.924 150.466 99.992  1.00 47.33  ? 166 SER D C   1 
ATOM   15422 O O   . SER D 1 166 ? 174.757 150.107 100.135 1.00 49.33  ? 166 SER D O   1 
ATOM   15423 C CB  . SER D 1 166 ? 177.911 149.167 100.829 1.00 51.74  ? 166 SER D CB  1 
ATOM   15424 O OG  . SER D 1 166 ? 177.230 148.002 100.411 1.00 52.60  ? 166 SER D OG  1 
ATOM   15425 N N   . ALA D 1 167 ? 176.356 150.957 98.829  1.00 47.91  ? 167 ALA D N   1 
ATOM   15426 C CA  . ALA D 1 167 ? 175.484 151.098 97.666  1.00 49.85  ? 167 ALA D CA  1 
ATOM   15427 C C   . ALA D 1 167 ? 174.840 149.769 97.224  1.00 49.78  ? 167 ALA D C   1 
ATOM   15428 O O   . ALA D 1 167 ? 173.696 149.765 96.781  1.00 48.28  ? 167 ALA D O   1 
ATOM   15429 C CB  . ALA D 1 167 ? 176.306 151.727 96.535  1.00 49.79  ? 167 ALA D CB  1 
ATOM   15430 N N   . LEU D 1 168 ? 175.525 148.633 97.404  1.00 47.31  ? 168 LEU D N   1 
ATOM   15431 C CA  . LEU D 1 168 ? 174.981 147.308 97.094  1.00 47.78  ? 168 LEU D CA  1 
ATOM   15432 C C   . LEU D 1 168 ? 173.840 146.907 98.042  1.00 42.89  ? 168 LEU D C   1 
ATOM   15433 O O   . LEU D 1 168 ? 172.815 146.414 97.585  1.00 42.13  ? 168 LEU D O   1 
ATOM   15434 C CB  . LEU D 1 168 ? 176.136 146.293 97.077  1.00 47.83  ? 168 LEU D CB  1 
ATOM   15435 C CG  . LEU D 1 168 ? 175.706 144.852 96.749  1.00 47.91  ? 168 LEU D CG  1 
ATOM   15436 C CD1 . LEU D 1 168 ? 175.037 144.727 95.383  1.00 42.36  ? 168 LEU D CD1 1 
ATOM   15437 C CD2 . LEU D 1 168 ? 176.923 143.935 96.755  1.00 47.90  ? 168 LEU D CD2 1 
ATOM   15438 N N   . HIS D 1 169 ? 173.957 147.183 99.343  1.00 37.43  ? 169 HIS D N   1 
ATOM   15439 C CA  . HIS D 1 169 ? 172.845 147.004 100.280 1.00 37.14  ? 169 HIS D CA  1 
ATOM   15440 C C   . HIS D 1 169 ? 171.635 147.856 99.893  1.00 41.28  ? 169 HIS D C   1 
ATOM   15441 O O   . HIS D 1 169 ? 170.507 147.327 99.948  1.00 41.83  ? 169 HIS D O   1 
ATOM   15442 C CB  . HIS D 1 169 ? 173.305 147.340 101.707 1.00 38.00  ? 169 HIS D CB  1 
ATOM   15443 C CG  . HIS D 1 169 ? 174.219 146.325 102.311 1.00 40.71  ? 169 HIS D CG  1 
ATOM   15444 N ND1 . HIS D 1 169 ? 175.503 146.637 102.716 1.00 38.21  ? 169 HIS D ND1 1 
ATOM   15445 C CD2 . HIS D 1 169 ? 174.041 145.016 102.590 1.00 37.10  ? 169 HIS D CD2 1 
ATOM   15446 C CE1 . HIS D 1 169 ? 176.079 145.561 103.215 1.00 37.16  ? 169 HIS D CE1 1 
ATOM   15447 N NE2 . HIS D 1 169 ? 175.201 144.553 103.150 1.00 40.97  ? 169 HIS D NE2 1 
ATOM   15448 N N   . ILE D 1 170 ? 171.853 149.113 99.495  1.00 45.07  ? 170 ILE D N   1 
ATOM   15449 C CA  . ILE D 1 170 ? 170.775 149.998 99.029  1.00 40.02  ? 170 ILE D CA  1 
ATOM   15450 C C   . ILE D 1 170 ? 170.135 149.460 97.745  1.00 43.81  ? 170 ILE D C   1 
ATOM   15451 O O   . ILE D 1 170 ? 168.912 149.404 97.670  1.00 44.41  ? 170 ILE D O   1 
ATOM   15452 C CB  . ILE D 1 170 ? 171.259 151.452 98.857  1.00 47.81  ? 170 ILE D CB  1 
ATOM   15453 C CG1 . ILE D 1 170 ? 171.860 152.011 100.161 1.00 44.88  ? 170 ILE D CG1 1 
ATOM   15454 C CG2 . ILE D 1 170 ? 170.100 152.365 98.428  1.00 45.86  ? 170 ILE D CG2 1 
ATOM   15455 C CD1 . ILE D 1 170 ? 172.615 153.327 99.976  1.00 46.62  ? 170 ILE D CD1 1 
ATOM   15456 N N   . ALA D 1 171 ? 170.914 149.025 96.750  1.00 42.00  ? 171 ALA D N   1 
ATOM   15457 C CA  . ALA D 1 171 ? 170.379 148.471 95.507  1.00 39.18  ? 171 ALA D CA  1 
ATOM   15458 C C   . ALA D 1 171 ? 169.512 147.222 95.746  1.00 43.51  ? 171 ALA D C   1 
ATOM   15459 O O   . ALA D 1 171 ? 168.449 147.076 95.143  1.00 41.92  ? 171 ALA D O   1 
ATOM   15460 C CB  . ALA D 1 171 ? 171.549 148.157 94.573  1.00 40.49  ? 171 ALA D CB  1 
ATOM   15461 N N   . ILE D 1 172 ? 169.944 146.347 96.661  1.00 46.49  ? 172 ILE D N   1 
ATOM   15462 C CA  . ILE D 1 172 ? 169.189 145.160 97.063  1.00 39.84  ? 172 ILE D CA  1 
ATOM   15463 C C   . ILE D 1 172 ? 167.894 145.567 97.764  1.00 42.36  ? 172 ILE D C   1 
ATOM   15464 O O   . ILE D 1 172 ? 166.834 145.147 97.323  1.00 43.71  ? 172 ILE D O   1 
ATOM   15465 C CB  . ILE D 1 172 ? 170.058 144.212 97.912  1.00 40.89  ? 172 ILE D CB  1 
ATOM   15466 C CG1 . ILE D 1 172 ? 171.207 143.668 97.041  1.00 42.53  ? 172 ILE D CG1 1 
ATOM   15467 C CG2 . ILE D 1 172 ? 169.249 143.039 98.486  1.00 34.68  ? 172 ILE D CG2 1 
ATOM   15468 C CD1 . ILE D 1 172 ? 172.290 142.948 97.823  1.00 40.21  ? 172 ILE D CD1 1 
ATOM   15469 N N   . GLU D 1 173 ? 167.918 146.421 98.785  1.00 40.71  ? 173 GLU D N   1 
ATOM   15470 C CA  . GLU D 1 173 ? 166.688 146.862 99.468  1.00 38.66  ? 173 GLU D CA  1 
ATOM   15471 C C   . GLU D 1 173 ? 165.743 147.664 98.551  1.00 44.94  ? 173 GLU D C   1 
ATOM   15472 O O   . GLU D 1 173 ? 164.525 147.515 98.643  1.00 46.37  ? 173 GLU D O   1 
ATOM   15473 C CB  . GLU D 1 173 ? 167.075 147.621 100.744 1.00 44.81  ? 173 GLU D CB  1 
ATOM   15474 C CG  . GLU D 1 173 ? 165.986 148.462 101.432 1.00 46.59  ? 173 GLU D CG  1 
ATOM   15475 C CD  . GLU D 1 173 ? 164.604 147.821 101.589 1.00 49.52  ? 173 GLU D CD  1 
ATOM   15476 O OE1 . GLU D 1 173 ? 164.512 146.578 101.728 1.00 51.02  ? 173 GLU D OE1 1 
ATOM   15477 O OE2 . GLU D 1 173 ? 163.617 148.590 101.629 1.00 46.27  ? 173 GLU D OE2 1 
ATOM   15478 N N   . LYS D 1 174 ? 166.250 148.453 97.596  1.00 48.54  ? 174 LYS D N   1 
ATOM   15479 C CA  . LYS D 1 174 ? 165.441 149.109 96.553  1.00 44.59  ? 174 LYS D CA  1 
ATOM   15480 C C   . LYS D 1 174 ? 164.929 148.158 95.457  1.00 47.17  ? 174 LYS D C   1 
ATOM   15481 O O   . LYS D 1 174 ? 164.237 148.604 94.546  1.00 50.48  ? 174 LYS D O   1 
ATOM   15482 C CB  . LYS D 1 174 ? 166.197 150.320 95.983  1.00 46.75  ? 174 LYS D CB  1 
ATOM   15483 C CG  . LYS D 1 174 ? 166.295 151.500 96.973  1.00 48.95  ? 174 LYS D CG  1 
ATOM   15484 C CD  . LYS D 1 174 ? 164.941 152.193 97.178  1.00 47.01  ? 174 LYS D CD  1 
ATOM   15485 C CE  . LYS D 1 174 ? 165.024 153.333 98.199  1.00 48.20  ? 174 LYS D CE  1 
ATOM   15486 N NZ  . LYS D 1 174 ? 163.673 153.861 98.515  1.00 50.28  ? 174 LYS D NZ  1 
ATOM   15487 N N   . ARG D 1 175 ? 165.220 146.854 95.560  1.00 46.26  ? 175 ARG D N   1 
ATOM   15488 C CA  . ARG D 1 175 ? 164.736 145.746 94.709  1.00 40.97  ? 175 ARG D CA  1 
ATOM   15489 C C   . ARG D 1 175 ? 165.128 145.839 93.228  1.00 45.43  ? 175 ARG D C   1 
ATOM   15490 O O   . ARG D 1 175 ? 164.458 145.256 92.378  1.00 48.21  ? 175 ARG D O   1 
ATOM   15491 C CB  . ARG D 1 175 ? 163.232 145.472 94.937  1.00 42.41  ? 175 ARG D CB  1 
ATOM   15492 C CG  . ARG D 1 175 ? 162.855 145.306 96.412  1.00 42.95  ? 175 ARG D CG  1 
ATOM   15493 C CD  . ARG D 1 175 ? 161.388 144.918 96.636  1.00 41.98  ? 175 ARG D CD  1 
ATOM   15494 N NE  . ARG D 1 175 ? 161.082 143.520 96.272  1.00 46.21  ? 175 ARG D NE  1 
ATOM   15495 C CZ  . ARG D 1 175 ? 161.188 142.449 97.036  1.00 48.84  ? 175 ARG D CZ  1 
ATOM   15496 N NH1 . ARG D 1 175 ? 160.750 141.297 96.635  1.00 46.57  ? 175 ARG D NH1 1 
ATOM   15497 N NH2 . ARG D 1 175 ? 161.747 142.497 98.205  1.00 45.51  ? 175 ARG D NH2 1 
ATOM   15498 N N   . SER D 1 176 ? 166.213 146.541 92.901  1.00 53.84  ? 176 SER D N   1 
ATOM   15499 C CA  . SER D 1 176 ? 166.697 146.659 91.520  1.00 55.41  ? 176 SER D CA  1 
ATOM   15500 C C   . SER D 1 176 ? 167.784 145.632 91.210  1.00 59.60  ? 176 SER D C   1 
ATOM   15501 O O   . SER D 1 176 ? 168.966 145.841 91.482  1.00 62.21  ? 176 SER D O   1 
ATOM   15502 C CB  . SER D 1 176 ? 167.167 148.082 91.219  1.00 57.59  ? 176 SER D CB  1 
ATOM   15503 O OG  . SER D 1 176 ? 167.658 148.136 89.891  1.00 60.39  ? 176 SER D OG  1 
ATOM   15504 N N   . LEU D 1 177 ? 167.400 144.521 90.579  1.00 53.30  ? 177 LEU D N   1 
ATOM   15505 C CA  . LEU D 1 177 ? 168.356 143.557 90.040  1.00 54.95  ? 177 LEU D CA  1 
ATOM   15506 C C   . LEU D 1 177 ? 169.232 144.180 88.942  1.00 58.77  ? 177 LEU D C   1 
ATOM   15507 O O   . LEU D 1 177 ? 170.419 143.883 88.873  1.00 60.49  ? 177 LEU D O   1 
ATOM   15508 C CB  . LEU D 1 177 ? 167.586 142.322 89.556  1.00 58.41  ? 177 LEU D CB  1 
ATOM   15509 C CG  . LEU D 1 177 ? 168.456 141.244 88.890  1.00 58.50  ? 177 LEU D CG  1 
ATOM   15510 C CD1 . LEU D 1 177 ? 169.533 140.702 89.826  1.00 55.66  ? 177 LEU D CD1 1 
ATOM   15511 C CD2 . LEU D 1 177 ? 167.560 140.088 88.467  1.00 55.77  ? 177 LEU D CD2 1 
ATOM   15512 N N   . GLN D 1 178 ? 168.693 145.099 88.138  1.00 60.63  ? 178 GLN D N   1 
ATOM   15513 C CA  . GLN D 1 178 ? 169.453 145.884 87.162  1.00 57.39  ? 178 GLN D CA  1 
ATOM   15514 C C   . GLN D 1 178 ? 170.600 146.654 87.824  1.00 59.61  ? 178 GLN D C   1 
ATOM   15515 O O   . GLN D 1 178 ? 171.730 146.622 87.347  1.00 60.93  ? 178 GLN D O   1 
ATOM   15516 C CB  . GLN D 1 178 ? 168.524 146.873 86.431  1.00 60.02  ? 178 GLN D CB  1 
ATOM   15517 C CG  . GLN D 1 178 ? 167.407 146.232 85.591  1.00 60.93  ? 178 GLN D CG  1 
ATOM   15518 C CD  . GLN D 1 178 ? 166.090 146.006 86.331  1.00 63.10  ? 178 GLN D CD  1 
ATOM   15519 O OE1 . GLN D 1 178 ? 166.034 145.736 87.521  1.00 63.21  ? 178 GLN D OE1 1 
ATOM   15520 N NE2 . GLN D 1 178 ? 164.970 146.086 85.649  1.00 62.38  ? 178 GLN D NE2 1 
ATOM   15521 N N   . CYS D 1 179 ? 170.336 147.320 88.949  1.00 57.63  ? 179 CYS D N   1 
ATOM   15522 C CA  . CYS D 1 179 ? 171.350 148.060 89.689  1.00 58.37  ? 179 CYS D CA  1 
ATOM   15523 C C   . CYS D 1 179 ? 172.340 147.131 90.413  1.00 61.15  ? 179 CYS D C   1 
ATOM   15524 O O   . CYS D 1 179 ? 173.542 147.387 90.387  1.00 58.28  ? 179 CYS D O   1 
ATOM   15525 C CB  . CYS D 1 179 ? 170.628 149.023 90.636  1.00 57.64  ? 179 CYS D CB  1 
ATOM   15526 S SG  . CYS D 1 179 ? 171.804 150.188 91.355  1.00 65.71  ? 179 CYS D SG  1 
ATOM   15527 N N   . VAL D 1 180 ? 171.882 146.007 90.983  1.00 56.94  ? 180 VAL D N   1 
ATOM   15528 C CA  . VAL D 1 180 ? 172.767 144.987 91.575  1.00 55.94  ? 180 VAL D CA  1 
ATOM   15529 C C   . VAL D 1 180 ? 173.731 144.418 90.534  1.00 55.90  ? 180 VAL D C   1 
ATOM   15530 O O   . VAL D 1 180 ? 174.938 144.399 90.771  1.00 51.90  ? 180 VAL D O   1 
ATOM   15531 C CB  . VAL D 1 180 ? 171.957 143.864 92.255  1.00 56.80  ? 180 VAL D CB  1 
ATOM   15532 C CG1 . VAL D 1 180 ? 172.834 142.682 92.668  1.00 56.73  ? 180 VAL D CG1 1 
ATOM   15533 C CG2 . VAL D 1 180 ? 171.262 144.389 93.513  1.00 50.70  ? 180 VAL D CG2 1 
ATOM   15534 N N   . LYS D 1 181 ? 173.236 144.028 89.351  1.00 57.73  ? 181 LYS D N   1 
ATOM   15535 C CA  . LYS D 1 181 ? 174.066 143.590 88.226  1.00 54.72  ? 181 LYS D CA  1 
ATOM   15536 C C   . LYS D 1 181 ? 175.104 144.646 87.849  1.00 56.10  ? 181 LYS D C   1 
ATOM   15537 O O   . LYS D 1 181 ? 176.284 144.337 87.760  1.00 58.39  ? 181 LYS D O   1 
ATOM   15538 C CB  . LYS D 1 181 ? 173.188 143.262 87.010  1.00 54.77  ? 181 LYS D CB  1 
ATOM   15539 C CG  . LYS D 1 181 ? 172.451 141.929 87.156  1.00 57.95  ? 181 LYS D CG  1 
ATOM   15540 C CD  . LYS D 1 181 ? 171.566 141.649 85.943  1.00 55.32  ? 181 LYS D CD  1 
ATOM   15541 C CE  . LYS D 1 181 ? 170.929 140.265 86.065  1.00 58.46  ? 181 LYS D CE  1 
ATOM   15542 N NZ  . LYS D 1 181 ? 170.177 139.900 84.845  1.00 59.62  ? 181 LYS D NZ  1 
ATOM   15543 N N   . LEU D 1 182 ? 174.677 145.897 87.681  1.00 62.48  ? 182 LEU D N   1 
ATOM   15544 C CA  . LEU D 1 182 ? 175.539 147.021 87.309  1.00 63.59  ? 182 LEU D CA  1 
ATOM   15545 C C   . LEU D 1 182 ? 176.663 147.260 88.334  1.00 64.68  ? 182 LEU D C   1 
ATOM   15546 O O   . LEU D 1 182 ? 177.817 147.439 87.952  1.00 65.73  ? 182 LEU D O   1 
ATOM   15547 C CB  . LEU D 1 182 ? 174.611 148.240 87.118  1.00 63.05  ? 182 LEU D CB  1 
ATOM   15548 C CG  . LEU D 1 182 ? 175.165 149.453 86.359  1.00 64.99  ? 182 LEU D CG  1 
ATOM   15549 C CD1 . LEU D 1 182 ? 173.996 150.392 86.081  1.00 65.72  ? 182 LEU D CD1 1 
ATOM   15550 C CD2 . LEU D 1 182 ? 176.214 150.241 87.130  1.00 64.85  ? 182 LEU D CD2 1 
ATOM   15551 N N   . LEU D 1 183 ? 176.353 147.215 89.629  1.00 62.07  ? 183 LEU D N   1 
ATOM   15552 C CA  . LEU D 1 183 ? 177.333 147.353 90.710  1.00 62.44  ? 183 LEU D CA  1 
ATOM   15553 C C   . LEU D 1 183 ? 178.304 146.164 90.775  1.00 62.36  ? 183 LEU D C   1 
ATOM   15554 O O   . LEU D 1 183 ? 179.515 146.361 90.867  1.00 62.52  ? 183 LEU D O   1 
ATOM   15555 C CB  . LEU D 1 183 ? 176.582 147.526 92.041  1.00 64.28  ? 183 LEU D CB  1 
ATOM   15556 C CG  . LEU D 1 183 ? 175.846 148.869 92.210  1.00 63.77  ? 183 LEU D CG  1 
ATOM   15557 C CD1 . LEU D 1 183 ? 174.977 148.795 93.459  1.00 59.74  ? 183 LEU D CD1 1 
ATOM   15558 C CD2 . LEU D 1 183 ? 176.801 150.042 92.390  1.00 63.64  ? 183 LEU D CD2 1 
ATOM   15559 N N   . VAL D 1 184 ? 177.807 144.927 90.691  1.00 65.58  ? 184 VAL D N   1 
ATOM   15560 C CA  . VAL D 1 184 ? 178.645 143.720 90.771  1.00 65.10  ? 184 VAL D CA  1 
ATOM   15561 C C   . VAL D 1 184 ? 179.552 143.572 89.542  1.00 66.00  ? 184 VAL D C   1 
ATOM   15562 O O   . VAL D 1 184 ? 180.734 143.276 89.696  1.00 66.98  ? 184 VAL D O   1 
ATOM   15563 C CB  . VAL D 1 184 ? 177.765 142.483 91.029  1.00 62.91  ? 184 VAL D CB  1 
ATOM   15564 C CG1 . VAL D 1 184 ? 178.528 141.165 90.893  1.00 61.25  ? 184 VAL D CG1 1 
ATOM   15565 C CG2 . VAL D 1 184 ? 177.203 142.535 92.457  1.00 61.08  ? 184 VAL D CG2 1 
ATOM   15566 N N   . GLU D 1 185 ? 179.067 143.892 88.339  1.00 64.04  ? 185 GLU D N   1 
ATOM   15567 C CA  . GLU D 1 185 ? 179.899 144.014 87.131  1.00 63.27  ? 185 GLU D CA  1 
ATOM   15568 C C   . GLU D 1 185 ? 181.058 145.010 87.284  1.00 67.14  ? 185 GLU D C   1 
ATOM   15569 O O   . GLU D 1 185 ? 182.108 144.838 86.667  1.00 68.44  ? 185 GLU D O   1 
ATOM   15570 C CB  . GLU D 1 185 ? 179.026 144.469 85.949  1.00 64.04  ? 185 GLU D CB  1 
ATOM   15571 C CG  . GLU D 1 185 ? 178.127 143.354 85.400  1.00 64.30  ? 185 GLU D CG  1 
ATOM   15572 C CD  . GLU D 1 185 ? 176.953 143.865 84.544  1.00 67.63  ? 185 GLU D CD  1 
ATOM   15573 O OE1 . GLU D 1 185 ? 176.973 145.024 84.073  1.00 67.54  ? 185 GLU D OE1 1 
ATOM   15574 O OE2 . GLU D 1 185 ? 176.021 143.069 84.280  1.00 67.10  ? 185 GLU D OE2 1 
ATOM   15575 N N   . ASN D 1 186 ? 180.890 146.050 88.107  1.00 67.55  ? 186 ASN D N   1 
ATOM   15576 C CA  . ASN D 1 186 ? 181.890 147.087 88.365  1.00 66.16  ? 186 ASN D CA  1 
ATOM   15577 C C   . ASN D 1 186 ? 182.723 146.861 89.643  1.00 67.95  ? 186 ASN D C   1 
ATOM   15578 O O   . ASN D 1 186 ? 183.453 147.753 90.070  1.00 68.18  ? 186 ASN D O   1 
ATOM   15579 C CB  . ASN D 1 186 ? 181.208 148.459 88.303  1.00 67.82  ? 186 ASN D CB  1 
ATOM   15580 C CG  . ASN D 1 186 ? 180.994 148.876 86.867  1.00 69.56  ? 186 ASN D CG  1 
ATOM   15581 O OD1 . ASN D 1 186 ? 181.896 149.395 86.219  1.00 71.14  ? 186 ASN D OD1 1 
ATOM   15582 N ND2 . ASN D 1 186 ? 179.826 148.654 86.316  1.00 68.22  ? 186 ASN D ND2 1 
ATOM   15583 N N   . GLY D 1 187 ? 182.659 145.677 90.253  1.00 67.30  ? 187 GLY D N   1 
ATOM   15584 C CA  . GLY D 1 187 ? 183.527 145.307 91.375  1.00 65.30  ? 187 GLY D CA  1 
ATOM   15585 C C   . GLY D 1 187 ? 182.974 145.598 92.774  1.00 66.03  ? 187 GLY D C   1 
ATOM   15586 O O   . GLY D 1 187 ? 183.758 145.719 93.719  1.00 64.72  ? 187 GLY D O   1 
ATOM   15587 N N   . ALA D 1 188 ? 181.650 145.694 92.936  1.00 65.30  ? 188 ALA D N   1 
ATOM   15588 C CA  . ALA D 1 188 ? 181.025 145.698 94.259  1.00 62.54  ? 188 ALA D CA  1 
ATOM   15589 C C   . ALA D 1 188 ? 181.358 144.411 95.035  1.00 65.14  ? 188 ALA D C   1 
ATOM   15590 O O   . ALA D 1 188 ? 181.058 143.306 94.589  1.00 67.46  ? 188 ALA D O   1 
ATOM   15591 C CB  . ALA D 1 188 ? 179.511 145.862 94.120  1.00 61.67  ? 188 ALA D CB  1 
ATOM   15592 N N   . ASP D 1 189 ? 181.964 144.550 96.208  1.00 62.71  ? 189 ASP D N   1 
ATOM   15593 C CA  . ASP D 1 189 ? 182.261 143.441 97.107  1.00 57.50  ? 189 ASP D CA  1 
ATOM   15594 C C   . ASP D 1 189 ? 180.970 142.913 97.749  1.00 61.34  ? 189 ASP D C   1 
ATOM   15595 O O   . ASP D 1 189 ? 180.287 143.610 98.498  1.00 63.15  ? 189 ASP D O   1 
ATOM   15596 C CB  . ASP D 1 189 ? 183.292 143.886 98.155  1.00 56.93  ? 189 ASP D CB  1 
ATOM   15597 C CG  . ASP D 1 189 ? 183.688 142.764 99.127  1.00 63.87  ? 189 ASP D CG  1 
ATOM   15598 O OD1 . ASP D 1 189 ? 183.272 141.605 98.914  1.00 65.06  ? 189 ASP D OD1 1 
ATOM   15599 O OD2 . ASP D 1 189 ? 184.458 143.043 100.070 1.00 64.28  ? 189 ASP D OD2 1 
ATOM   15600 N N   . VAL D 1 190 ? 180.631 141.661 97.460  1.00 55.81  ? 190 VAL D N   1 
ATOM   15601 C CA  . VAL D 1 190 ? 179.410 141.016 97.947  1.00 52.62  ? 190 VAL D CA  1 
ATOM   15602 C C   . VAL D 1 190 ? 179.521 140.597 99.423  1.00 51.90  ? 190 VAL D C   1 
ATOM   15603 O O   . VAL D 1 190 ? 178.543 140.160 100.015 1.00 54.55  ? 190 VAL D O   1 
ATOM   15604 C CB  . VAL D 1 190 ? 179.005 139.861 97.006  1.00 53.18  ? 190 VAL D CB  1 
ATOM   15605 C CG1 . VAL D 1 190 ? 177.582 139.377 97.271  1.00 55.26  ? 190 VAL D CG1 1 
ATOM   15606 C CG2 . VAL D 1 190 ? 179.032 140.291 95.534  1.00 50.73  ? 190 VAL D CG2 1 
ATOM   15607 N N   . HIS D 1 191 ? 180.689 140.754 100.056 1.00 53.07  ? 191 HIS D N   1 
ATOM   15608 C CA  . HIS D 1 191 ? 180.941 140.368 101.450 1.00 51.70  ? 191 HIS D CA  1 
ATOM   15609 C C   . HIS D 1 191 ? 181.099 141.544 102.422 1.00 53.46  ? 191 HIS D C   1 
ATOM   15610 O O   . HIS D 1 191 ? 181.654 141.374 103.508 1.00 55.90  ? 191 HIS D O   1 
ATOM   15611 C CB  . HIS D 1 191 ? 182.159 139.432 101.501 1.00 55.35  ? 191 HIS D CB  1 
ATOM   15612 C CG  . HIS D 1 191 ? 181.981 138.199 100.679 1.00 56.76  ? 191 HIS D CG  1 
ATOM   15613 N ND1 . HIS D 1 191 ? 181.488 137.022 101.209 1.00 53.20  ? 191 HIS D ND1 1 
ATOM   15614 C CD2 . HIS D 1 191 ? 182.214 137.957 99.370  1.00 54.86  ? 191 HIS D CD2 1 
ATOM   15615 C CE1 . HIS D 1 191 ? 181.430 136.106 100.263 1.00 54.53  ? 191 HIS D CE1 1 
ATOM   15616 N NE2 . HIS D 1 191 ? 181.870 136.657 99.125  1.00 56.23  ? 191 HIS D NE2 1 
ATOM   15617 N N   . LEU D 1 192 ? 180.629 142.748 102.078 1.00 55.46  ? 192 LEU D N   1 
ATOM   15618 C CA  . LEU D 1 192 ? 180.606 143.882 103.013 1.00 50.97  ? 192 LEU D CA  1 
ATOM   15619 C C   . LEU D 1 192 ? 179.567 143.671 104.124 1.00 50.27  ? 192 LEU D C   1 
ATOM   15620 O O   . LEU D 1 192 ? 178.412 143.362 103.839 1.00 51.79  ? 192 LEU D O   1 
ATOM   15621 C CB  . LEU D 1 192 ? 180.309 145.185 102.249 1.00 50.96  ? 192 LEU D CB  1 
ATOM   15622 C CG  . LEU D 1 192 ? 181.351 145.556 101.182 1.00 55.37  ? 192 LEU D CG  1 
ATOM   15623 C CD1 . LEU D 1 192 ? 180.926 146.832 100.462 1.00 53.04  ? 192 LEU D CD1 1 
ATOM   15624 C CD2 . LEU D 1 192 ? 182.737 145.776 101.778 1.00 53.25  ? 192 LEU D CD2 1 
ATOM   15625 N N   . ARG D 1 193 ? 179.932 143.984 105.380 1.00 46.32  ? 193 ARG D N   1 
ATOM   15626 C CA  . ARG D 1 193 ? 178.992 143.760 106.522 1.00 45.39  ? 193 ARG D CA  1 
ATOM   15627 C C   . ARG D 1 193 ? 178.390 145.037 107.098 1.00 45.01  ? 193 ARG D C   1 
ATOM   15628 O O   . ARG D 1 193 ? 179.094 145.723 107.866 1.00 49.62  ? 193 ARG D O   1 
ATOM   15629 C CB  . ARG D 1 193 ? 179.646 143.112 107.757 1.00 51.26  ? 193 ARG D CB  1 
ATOM   15630 C CG  . ARG D 1 193 ? 179.837 141.591 107.718 1.00 44.87  ? 193 ARG D CG  1 
ATOM   15631 C CD  . ARG D 1 193 ? 180.937 141.150 106.754 1.00 48.83  ? 193 ARG D CD  1 
ATOM   15632 N NE  . ARG D 1 193 ? 180.968 139.699 106.635 1.00 52.18  ? 193 ARG D NE  1 
ATOM   15633 C CZ  . ARG D 1 193 ? 181.822 139.018 105.879 1.00 49.70  ? 193 ARG D CZ  1 
ATOM   15634 N NH1 . ARG D 1 193 ? 181.763 137.698 105.840 1.00 48.34  ? 193 ARG D NH1 1 
ATOM   15635 N NH2 . ARG D 1 193 ? 182.729 139.658 105.164 1.00 48.53  ? 193 ARG D NH2 1 
ATOM   15636 N N   . ALA D 1 194 ? 177.147 145.340 106.749 1.00 37.89  ? 194 ALA D N   1 
ATOM   15637 C CA  . ALA D 1 194 ? 176.400 146.416 107.390 1.00 32.82  ? 194 ALA D CA  1 
ATOM   15638 C C   . ALA D 1 194 ? 176.223 146.083 108.877 1.00 39.43  ? 194 ALA D C   1 
ATOM   15639 O O   . ALA D 1 194 ? 175.362 145.294 109.247 1.00 41.45  ? 194 ALA D O   1 
ATOM   15640 C CB  . ALA D 1 194 ? 175.066 146.590 106.664 1.00 30.93  ? 194 ALA D CB  1 
ATOM   15641 N N   . CYS D 1 195 ? 177.089 146.615 109.738 1.00 41.11  ? 195 CYS D N   1 
ATOM   15642 C CA  . CYS D 1 195 ? 177.295 146.153 111.116 1.00 40.11  ? 195 CYS D CA  1 
ATOM   15643 C C   . CYS D 1 195 ? 177.038 147.224 112.195 1.00 49.12  ? 195 CYS D C   1 
ATOM   15644 O O   . CYS D 1 195 ? 177.082 146.912 113.387 1.00 51.56  ? 195 CYS D O   1 
ATOM   15645 C CB  . CYS D 1 195 ? 178.718 145.585 111.213 1.00 43.03  ? 195 CYS D CB  1 
ATOM   15646 S SG  . CYS D 1 195 ? 179.949 146.860 110.824 1.00 60.88  ? 195 CYS D SG  1 
ATOM   15647 N N   . GLY D 1 196 ? 176.754 148.474 111.808 1.00 44.92  ? 196 GLY D N   1 
ATOM   15648 C CA  . GLY D 1 196 ? 176.380 149.539 112.737 1.00 41.01  ? 196 GLY D CA  1 
ATOM   15649 C C   . GLY D 1 196 ? 175.112 149.237 113.546 1.00 40.83  ? 196 GLY D C   1 
ATOM   15650 O O   . GLY D 1 196 ? 174.357 148.317 113.243 1.00 44.42  ? 196 GLY D O   1 
ATOM   15651 N N   . ARG D 1 197 ? 174.854 150.017 114.601 1.00 40.01  ? 197 ARG D N   1 
ATOM   15652 C CA  . ARG D 1 197 ? 173.793 149.750 115.581 1.00 42.34  ? 197 ARG D CA  1 
ATOM   15653 C C   . ARG D 1 197 ? 172.388 149.623 114.984 1.00 41.54  ? 197 ARG D C   1 
ATOM   15654 O O   . ARG D 1 197 ? 171.571 148.902 115.541 1.00 42.13  ? 197 ARG D O   1 
ATOM   15655 C CB  . ARG D 1 197 ? 173.856 150.829 116.679 1.00 42.99  ? 197 ARG D CB  1 
ATOM   15656 C CG  . ARG D 1 197 ? 172.978 150.562 117.909 1.00 41.25  ? 197 ARG D CG  1 
ATOM   15657 C CD  . ARG D 1 197 ? 173.310 149.215 118.552 1.00 41.36  ? 197 ARG D CD  1 
ATOM   15658 N NE  . ARG D 1 197 ? 172.570 148.992 119.799 1.00 49.80  ? 197 ARG D NE  1 
ATOM   15659 C CZ  . ARG D 1 197 ? 172.535 147.863 120.478 1.00 51.78  ? 197 ARG D CZ  1 
ATOM   15660 N NH1 . ARG D 1 197 ? 171.835 147.781 121.567 1.00 46.12  ? 197 ARG D NH1 1 
ATOM   15661 N NH2 . ARG D 1 197 ? 173.188 146.802 120.098 1.00 48.39  ? 197 ARG D NH2 1 
ATOM   15662 N N   . PHE D 1 198 ? 172.089 150.246 113.847 1.00 36.53  ? 198 PHE D N   1 
ATOM   15663 C CA  . PHE D 1 198 ? 170.812 150.059 113.152 1.00 34.34  ? 198 PHE D CA  1 
ATOM   15664 C C   . PHE D 1 198 ? 170.627 148.637 112.592 1.00 36.80  ? 198 PHE D C   1 
ATOM   15665 O O   . PHE D 1 198 ? 169.511 148.146 112.476 1.00 31.80  ? 198 PHE D O   1 
ATOM   15666 C CB  . PHE D 1 198 ? 170.720 151.083 112.018 1.00 29.26  ? 198 PHE D CB  1 
ATOM   15667 C CG  . PHE D 1 198 ? 169.444 150.949 111.222 1.00 32.98  ? 198 PHE D CG  1 
ATOM   15668 C CD1 . PHE D 1 198 ? 168.217 151.275 111.812 1.00 31.96  ? 198 PHE D CD1 1 
ATOM   15669 C CD2 . PHE D 1 198 ? 169.479 150.404 109.930 1.00 31.66  ? 198 PHE D CD2 1 
ATOM   15670 C CE1 . PHE D 1 198 ? 167.025 151.040 111.119 1.00 25.65  ? 198 PHE D CE1 1 
ATOM   15671 C CE2 . PHE D 1 198 ? 168.284 150.178 109.229 1.00 28.53  ? 198 PHE D CE2 1 
ATOM   15672 C CZ  . PHE D 1 198 ? 167.060 150.495 109.819 1.00 31.14  ? 198 PHE D CZ  1 
ATOM   15673 N N   . PHE D 1 199 ? 171.716 147.957 112.249 1.00 39.37  ? 199 PHE D N   1 
ATOM   15674 C CA  . PHE D 1 199 ? 171.696 146.631 111.640 1.00 28.27  ? 199 PHE D CA  1 
ATOM   15675 C C   . PHE D 1 199 ? 171.830 145.483 112.642 1.00 34.31  ? 199 PHE D C   1 
ATOM   15676 O O   . PHE D 1 199 ? 171.732 144.322 112.261 1.00 38.75  ? 199 PHE D O   1 
ATOM   15677 C CB  . PHE D 1 199 ? 172.811 146.583 110.604 1.00 24.88  ? 199 PHE D CB  1 
ATOM   15678 C CG  . PHE D 1 199 ? 172.684 147.656 109.559 1.00 30.56  ? 199 PHE D CG  1 
ATOM   15679 C CD1 . PHE D 1 199 ? 171.619 147.613 108.649 1.00 31.32  ? 199 PHE D CD1 1 
ATOM   15680 C CD2 . PHE D 1 199 ? 173.616 148.704 109.500 1.00 32.22  ? 199 PHE D CD2 1 
ATOM   15681 C CE1 . PHE D 1 199 ? 171.504 148.594 107.651 1.00 31.58  ? 199 PHE D CE1 1 
ATOM   15682 C CE2 . PHE D 1 199 ? 173.495 149.678 108.504 1.00 30.84  ? 199 PHE D CE2 1 
ATOM   15683 C CZ  . PHE D 1 199 ? 172.446 149.625 107.581 1.00 29.86  ? 199 PHE D CZ  1 
ATOM   15684 N N   . GLN D 1 200 ? 172.069 145.779 113.914 1.00 38.32  ? 200 GLN D N   1 
ATOM   15685 C CA  . GLN D 1 200 ? 172.121 144.808 115.002 1.00 33.63  ? 200 GLN D CA  1 
ATOM   15686 C C   . GLN D 1 200 ? 170.711 144.472 115.501 1.00 38.74  ? 200 GLN D C   1 
ATOM   15687 O O   . GLN D 1 200 ? 169.793 145.274 115.375 1.00 40.13  ? 200 GLN D O   1 
ATOM   15688 C CB  . GLN D 1 200 ? 173.000 145.363 116.131 1.00 36.97  ? 200 GLN D CB  1 
ATOM   15689 C CG  . GLN D 1 200 ? 174.465 145.532 115.696 1.00 37.38  ? 200 GLN D CG  1 
ATOM   15690 C CD  . GLN D 1 200 ? 175.308 146.324 116.687 1.00 41.48  ? 200 GLN D CD  1 
ATOM   15691 O OE1 . GLN D 1 200 ? 174.964 146.511 117.847 1.00 44.86  ? 200 GLN D OE1 1 
ATOM   15692 N NE2 . GLN D 1 200 ? 176.432 146.851 116.260 1.00 38.94  ? 200 GLN D NE2 1 
ATOM   15693 N N   . LYS D 1 201 ? 170.516 143.300 116.111 1.00 42.97  ? 201 LYS D N   1 
ATOM   15694 C CA  . LYS D 1 201 ? 169.252 142.933 116.760 1.00 40.51  ? 201 LYS D CA  1 
ATOM   15695 C C   . LYS D 1 201 ? 169.226 143.473 118.196 1.00 46.35  ? 201 LYS D C   1 
ATOM   15696 O O   . LYS D 1 201 ? 170.088 143.137 119.001 1.00 50.81  ? 201 LYS D O   1 
ATOM   15697 C CB  . LYS D 1 201 ? 169.081 141.409 116.677 1.00 45.47  ? 201 LYS D CB  1 
ATOM   15698 C CG  . LYS D 1 201 ? 167.754 140.871 117.224 1.00 47.23  ? 201 LYS D CG  1 
ATOM   15699 C CD  . LYS D 1 201 ? 166.514 141.410 116.509 1.00 50.49  ? 201 LYS D CD  1 
ATOM   15700 C CE  . LYS D 1 201 ? 165.268 140.721 117.065 1.00 52.40  ? 201 LYS D CE  1 
ATOM   15701 N NZ  . LYS D 1 201 ? 164.027 141.231 116.454 1.00 51.61  ? 201 LYS D NZ  1 
ATOM   15702 N N   . HIS D 1 202 ? 168.244 144.311 118.521 1.00 42.54  ? 202 HIS D N   1 
ATOM   15703 C CA  . HIS D 1 202 ? 167.983 144.869 119.854 1.00 42.16  ? 202 HIS D CA  1 
ATOM   15704 C C   . HIS D 1 202 ? 166.535 145.355 119.946 1.00 46.50  ? 202 HIS D C   1 
ATOM   15705 O O   . HIS D 1 202 ? 165.797 145.307 118.962 1.00 48.39  ? 202 HIS D O   1 
ATOM   15706 C CB  . HIS D 1 202 ? 168.979 145.997 120.159 1.00 42.71  ? 202 HIS D CB  1 
ATOM   15707 C CG  . HIS D 1 202 ? 169.044 147.044 119.098 1.00 45.17  ? 202 HIS D CG  1 
ATOM   15708 N ND1 . HIS D 1 202 ? 168.113 148.061 119.006 1.00 47.80  ? 202 HIS D ND1 1 
ATOM   15709 C CD2 . HIS D 1 202 ? 169.919 147.239 118.089 1.00 44.55  ? 202 HIS D CD2 1 
ATOM   15710 C CE1 . HIS D 1 202 ? 168.412 148.836 117.984 1.00 43.22  ? 202 HIS D CE1 1 
ATOM   15711 N NE2 . HIS D 1 202 ? 169.518 148.353 117.405 1.00 39.99  ? 202 HIS D NE2 1 
ATOM   15712 N N   . GLN D 1 203 ? 166.102 145.802 121.133 1.00 57.48  ? 203 GLN D N   1 
ATOM   15713 C CA  . GLN D 1 203 ? 164.668 146.179 121.347 1.00 57.27  ? 203 GLN D CA  1 
ATOM   15714 C C   . GLN D 1 203 ? 164.338 147.535 120.706 1.00 56.93  ? 203 GLN D C   1 
ATOM   15715 O O   . GLN D 1 203 ? 163.137 147.813 120.526 1.00 56.55  ? 203 GLN D O   1 
ATOM   15716 C CB  . GLN D 1 203 ? 164.370 146.151 122.851 1.00 54.65  ? 203 GLN D CB  1 
ATOM   15717 C CG  . GLN D 1 203 ? 164.428 144.732 123.440 1.00 55.07  ? 203 GLN D CG  1 
ATOM   15718 C CD  . GLN D 1 203 ? 164.115 144.716 124.916 1.00 60.45  ? 203 GLN D CD  1 
ATOM   15719 O OE1 . GLN D 1 203 ? 164.143 143.673 125.566 1.00 61.84  ? 203 GLN D OE1 1 
ATOM   15720 N NE2 . GLN D 1 203 ? 163.815 145.884 125.460 1.00 58.07  ? 203 GLN D NE2 1 
ATOM   15721 N N   . GLY D 1 204 ? 165.348 148.339 120.375 1.00 49.41  ? 204 GLY D N   1 
ATOM   15722 C CA  . GLY D 1 204 ? 165.192 149.653 119.756 1.00 46.63  ? 204 GLY D CA  1 
ATOM   15723 C C   . GLY D 1 204 ? 164.897 149.620 118.257 1.00 45.77  ? 204 GLY D C   1 
ATOM   15724 O O   . GLY D 1 204 ? 164.444 148.621 117.701 1.00 52.01  ? 204 GLY D O   1 
ATOM   15725 N N   . THR D 1 205 ? 165.126 150.742 117.584 1.00 45.69  ? 205 THR D N   1 
ATOM   15726 C CA  . THR D 1 205 ? 164.863 150.903 116.148 1.00 46.05  ? 205 THR D CA  1 
ATOM   15727 C C   . THR D 1 205 ? 166.001 150.299 115.320 1.00 42.92  ? 205 THR D C   1 
ATOM   15728 O O   . THR D 1 205 ? 167.109 150.831 115.261 1.00 43.37  ? 205 THR D O   1 
ATOM   15729 C CB  . THR D 1 205 ? 164.554 152.376 115.805 1.00 46.43  ? 205 THR D CB  1 
ATOM   15730 O OG1 . THR D 1 205 ? 165.515 153.260 116.331 1.00 53.17  ? 205 THR D OG1 1 
ATOM   15731 C CG2 . THR D 1 205 ? 163.217 152.778 116.406 1.00 45.87  ? 205 THR D CG2 1 
ATOM   15732 N N   . CYS D 1 206 ? 165.746 149.145 114.701 1.00 36.44  ? 206 CYS D N   1 
ATOM   15733 C CA  . CYS D 1 206 ? 166.736 148.383 113.946 1.00 31.21  ? 206 CYS D CA  1 
ATOM   15734 C C   . CYS D 1 206 ? 166.122 147.481 112.869 1.00 28.99  ? 206 CYS D C   1 
ATOM   15735 O O   . CYS D 1 206 ? 164.933 147.164 112.881 1.00 33.97  ? 206 CYS D O   1 
ATOM   15736 C CB  . CYS D 1 206 ? 167.598 147.567 114.918 1.00 34.69  ? 206 CYS D CB  1 
ATOM   15737 S SG  . CYS D 1 206 ? 166.742 146.136 115.618 1.00 30.25  ? 206 CYS D SG  1 
ATOM   15738 N N   . PHE D 1 207 ? 166.971 147.022 111.958 1.00 26.59  ? 207 PHE D N   1 
ATOM   15739 C CA  . PHE D 1 207 ? 166.673 146.036 110.929 1.00 22.30  ? 207 PHE D CA  1 
ATOM   15740 C C   . PHE D 1 207 ? 167.829 145.036 110.850 1.00 22.78  ? 207 PHE D C   1 
ATOM   15741 O O   . PHE D 1 207 ? 168.775 145.215 110.092 1.00 30.79  ? 207 PHE D O   1 
ATOM   15742 C CB  . PHE D 1 207 ? 166.411 146.772 109.608 1.00 24.89  ? 207 PHE D CB  1 
ATOM   15743 C CG  . PHE D 1 207 ? 166.168 145.929 108.370 1.00 23.88  ? 207 PHE D CG  1 
ATOM   15744 C CD1 . PHE D 1 207 ? 165.563 144.661 108.424 1.00 26.38  ? 207 PHE D CD1 1 
ATOM   15745 C CD2 . PHE D 1 207 ? 166.501 146.471 107.119 1.00 30.94  ? 207 PHE D CD2 1 
ATOM   15746 C CE1 . PHE D 1 207 ? 165.304 143.951 107.241 1.00 21.95  ? 207 PHE D CE1 1 
ATOM   15747 C CE2 . PHE D 1 207 ? 166.251 145.760 105.936 1.00 24.61  ? 207 PHE D CE2 1 
ATOM   15748 C CZ  . PHE D 1 207 ? 165.643 144.498 105.998 1.00 28.13  ? 207 PHE D CZ  1 
ATOM   15749 N N   . TYR D 1 208 ? 167.765 143.981 111.660 1.00 22.04  ? 208 TYR D N   1 
ATOM   15750 C CA  . TYR D 1 208 ? 168.649 142.829 111.518 1.00 28.34  ? 208 TYR D CA  1 
ATOM   15751 C C   . TYR D 1 208 ? 168.189 141.914 110.375 1.00 30.84  ? 208 TYR D C   1 
ATOM   15752 O O   . TYR D 1 208 ? 167.046 141.473 110.340 1.00 34.14  ? 208 TYR D O   1 
ATOM   15753 C CB  . TYR D 1 208 ? 168.760 142.068 112.847 1.00 24.31  ? 208 TYR D CB  1 
ATOM   15754 C CG  . TYR D 1 208 ? 169.723 140.903 112.776 1.00 24.46  ? 208 TYR D CG  1 
ATOM   15755 C CD1 . TYR D 1 208 ? 171.102 141.128 112.892 1.00 27.59  ? 208 TYR D CD1 1 
ATOM   15756 C CD2 . TYR D 1 208 ? 169.252 139.610 112.487 1.00 28.51  ? 208 TYR D CD2 1 
ATOM   15757 C CE1 . TYR D 1 208 ? 172.018 140.081 112.695 1.00 32.19  ? 208 TYR D CE1 1 
ATOM   15758 C CE2 . TYR D 1 208 ? 170.167 138.564 112.276 1.00 26.46  ? 208 TYR D CE2 1 
ATOM   15759 C CZ  . TYR D 1 208 ? 171.549 138.797 112.381 1.00 32.07  ? 208 TYR D CZ  1 
ATOM   15760 O OH  . TYR D 1 208 ? 172.422 137.792 112.137 1.00 37.95  ? 208 TYR D OH  1 
ATOM   15761 N N   . PHE D 1 209 ? 169.101 141.571 109.470 1.00 27.39  ? 209 PHE D N   1 
ATOM   15762 C CA  . PHE D 1 209 ? 168.886 140.676 108.329 1.00 29.65  ? 209 PHE D CA  1 
ATOM   15763 C C   . PHE D 1 209 ? 170.110 139.777 108.110 1.00 27.13  ? 209 PHE D C   1 
ATOM   15764 O O   . PHE D 1 209 ? 170.374 139.306 107.011 1.00 38.68  ? 209 PHE D O   1 
ATOM   15765 C CB  . PHE D 1 209 ? 168.572 141.516 107.077 1.00 25.78  ? 209 PHE D CB  1 
ATOM   15766 C CG  . PHE D 1 209 ? 169.587 142.602 106.738 1.00 23.16  ? 209 PHE D CG  1 
ATOM   15767 C CD1 . PHE D 1 209 ? 170.819 142.297 106.126 1.00 24.16  ? 209 PHE D CD1 1 
ATOM   15768 C CD2 . PHE D 1 209 ? 169.288 143.941 107.036 1.00 22.88  ? 209 PHE D CD2 1 
ATOM   15769 C CE1 . PHE D 1 209 ? 171.751 143.315 105.853 1.00 27.74  ? 209 PHE D CE1 1 
ATOM   15770 C CE2 . PHE D 1 209 ? 170.198 144.960 106.721 1.00 29.89  ? 209 PHE D CE2 1 
ATOM   15771 C CZ  . PHE D 1 209 ? 171.440 144.649 106.148 1.00 27.63  ? 209 PHE D CZ  1 
ATOM   15772 N N   . GLY D 1 210 ? 170.903 139.554 109.150 1.00 23.23  ? 210 GLY D N   1 
ATOM   15773 C CA  . GLY D 1 210 ? 172.321 139.295 108.968 1.00 27.90  ? 210 GLY D CA  1 
ATOM   15774 C C   . GLY D 1 210 ? 172.992 140.648 108.746 1.00 41.48  ? 210 GLY D C   1 
ATOM   15775 O O   . GLY D 1 210 ? 172.438 141.684 109.117 1.00 52.52  ? 210 GLY D O   1 
ATOM   15776 N N   . GLU D 1 211 ? 174.152 140.680 108.102 1.00 36.84  ? 211 GLU D N   1 
ATOM   15777 C CA  . GLU D 1 211 ? 174.819 141.953 107.782 1.00 31.99  ? 211 GLU D CA  1 
ATOM   15778 C C   . GLU D 1 211 ? 175.237 142.048 106.311 1.00 33.69  ? 211 GLU D C   1 
ATOM   15779 O O   . GLU D 1 211 ? 175.683 143.087 105.844 1.00 35.37  ? 211 GLU D O   1 
ATOM   15780 C CB  . GLU D 1 211 ? 176.022 142.137 108.715 1.00 32.02  ? 211 GLU D CB  1 
ATOM   15781 C CG  . GLU D 1 211 ? 175.600 142.190 110.191 1.00 30.49  ? 211 GLU D CG  1 
ATOM   15782 C CD  . GLU D 1 211 ? 176.787 142.301 111.151 1.00 40.22  ? 211 GLU D CD  1 
ATOM   15783 O OE1 . GLU D 1 211 ? 177.937 141.977 110.774 1.00 43.91  ? 211 GLU D OE1 1 
ATOM   15784 O OE2 . GLU D 1 211 ? 176.564 142.649 112.327 1.00 42.80  ? 211 GLU D OE2 1 
ATOM   15785 N N   . LEU D 1 212 ? 175.108 140.952 105.563 1.00 38.64  ? 212 LEU D N   1 
ATOM   15786 C CA  . LEU D 1 212 ? 175.678 140.958 104.185 1.00 33.70  ? 212 LEU D CA  1 
ATOM   15787 C C   . LEU D 1 212 ? 174.600 141.031 103.102 1.00 33.76  ? 212 LEU D C   1 
ATOM   15788 O O   . LEU D 1 212 ? 173.439 140.671 103.382 1.00 40.09  ? 212 LEU D O   1 
ATOM   15789 C CB  . LEU D 1 212 ? 176.544 139.703 104.012 1.00 38.55  ? 212 LEU D CB  1 
ATOM   15790 C CG  . LEU D 1 212 ? 177.767 139.621 104.923 1.00 41.52  ? 212 LEU D CG  1 
ATOM   15791 C CD1 . LEU D 1 212 ? 177.349 139.424 106.374 1.00 40.34  ? 212 LEU D CD1 1 
ATOM   15792 C CD2 . LEU D 1 212 ? 178.696 138.500 104.484 1.00 38.83  ? 212 LEU D CD2 1 
ATOM   15793 N N   . PRO D 1 213 ? 174.955 141.480 101.878 1.00 36.26  ? 213 PRO D N   1 
ATOM   15794 C CA  . PRO D 1 213 ? 174.006 141.534 100.765 1.00 37.61  ? 213 PRO D CA  1 
ATOM   15795 C C   . PRO D 1 213 ? 173.217 140.226 100.623 1.00 37.40  ? 213 PRO D C   1 
ATOM   15796 O O   . PRO D 1 213 ? 172.002 140.295 100.569 1.00 35.74  ? 213 PRO D O   1 
ATOM   15797 C CB  . PRO D 1 213 ? 174.927 141.718 99.551  1.00 40.37  ? 213 PRO D CB  1 
ATOM   15798 C CG  . PRO D 1 213 ? 176.094 142.507 100.099 1.00 32.93  ? 213 PRO D CG  1 
ATOM   15799 C CD  . PRO D 1 213 ? 176.281 141.980 101.506 1.00 33.68  ? 213 PRO D CD  1 
ATOM   15800 N N   . LEU D 1 214 ? 173.905 139.081 100.562 1.00 34.17  ? 214 LEU D N   1 
ATOM   15801 C CA  . LEU D 1 214 ? 173.159 137.841 100.333 1.00 32.87  ? 214 LEU D CA  1 
ATOM   15802 C C   . LEU D 1 214 ? 172.092 137.589 101.406 1.00 26.47  ? 214 LEU D C   1 
ATOM   15803 O O   . LEU D 1 214 ? 170.974 137.192 101.090 1.00 32.33  ? 214 LEU D O   1 
ATOM   15804 C CB  . LEU D 1 214 ? 174.142 136.665 100.229 1.00 38.33  ? 214 LEU D CB  1 
ATOM   15805 C CG  . LEU D 1 214 ? 173.454 135.316 99.957  1.00 33.63  ? 214 LEU D CG  1 
ATOM   15806 C CD1 . LEU D 1 214 ? 172.840 135.276 98.566  1.00 34.10  ? 214 LEU D CD1 1 
ATOM   15807 C CD2 . LEU D 1 214 ? 174.446 134.174 100.079 1.00 32.84  ? 214 LEU D CD2 1 
ATOM   15808 N N   . SER D 1 215 ? 172.416 137.847 102.670 1.00 20.77  ? 215 SER D N   1 
ATOM   15809 C CA  . SER D 1 215 ? 171.462 137.702 103.766 1.00 14.71  ? 215 SER D CA  1 
ATOM   15810 C C   . SER D 1 215 ? 170.340 138.729 103.685 1.00 22.18  ? 215 SER D C   1 
ATOM   15811 O O   . SER D 1 215 ? 169.188 138.366 103.884 1.00 23.95  ? 215 SER D O   1 
ATOM   15812 C CB  . SER D 1 215 ? 172.153 137.770 105.121 1.00 26.47  ? 215 SER D CB  1 
ATOM   15813 O OG  . SER D 1 215 ? 173.277 136.914 105.151 1.00 34.27  ? 215 SER D OG  1 
ATOM   15814 N N   . LEU D 1 216 ? 170.628 139.968 103.279 1.00 36.54  ? 216 LEU D N   1 
ATOM   15815 C CA  . LEU D 1 216 ? 169.613 140.958 102.937 1.00 23.43  ? 216 LEU D CA  1 
ATOM   15816 C C   . LEU D 1 216 ? 168.704 140.438 101.821 1.00 28.15  ? 216 LEU D C   1 
ATOM   15817 O O   . LEU D 1 216 ? 167.508 140.324 102.039 1.00 38.38  ? 216 LEU D O   1 
ATOM   15818 C CB  . LEU D 1 216 ? 170.301 142.282 102.578 1.00 26.52  ? 216 LEU D CB  1 
ATOM   15819 C CG  . LEU D 1 216 ? 169.351 143.444 102.246 1.00 27.29  ? 216 LEU D CG  1 
ATOM   15820 C CD1 . LEU D 1 216 ? 168.416 143.829 103.387 1.00 23.30  ? 216 LEU D CD1 1 
ATOM   15821 C CD2 . LEU D 1 216 ? 170.200 144.654 101.891 1.00 25.38  ? 216 LEU D CD2 1 
ATOM   15822 N N   . ALA D 1 217 ? 169.249 140.037 100.669 1.00 26.06  ? 217 ALA D N   1 
ATOM   15823 C CA  . ALA D 1 217 ? 168.458 139.539 99.546  1.00 22.88  ? 217 ALA D CA  1 
ATOM   15824 C C   . ALA D 1 217 ? 167.573 138.329 99.907  1.00 31.61  ? 217 ALA D C   1 
ATOM   15825 O O   . ALA D 1 217 ? 166.442 138.218 99.437  1.00 31.82  ? 217 ALA D O   1 
ATOM   15826 C CB  . ALA D 1 217 ? 169.415 139.207 98.398  1.00 26.51  ? 217 ALA D CB  1 
ATOM   15827 N N   . ALA D 1 218 ? 168.054 137.430 100.771 1.00 32.97  ? 218 ALA D N   1 
ATOM   15828 C CA  . ALA D 1 218 ? 167.269 136.326 101.303 1.00 24.68  ? 218 ALA D CA  1 
ATOM   15829 C C   . ALA D 1 218 ? 166.177 136.800 102.276 1.00 24.51  ? 218 ALA D C   1 
ATOM   15830 O O   . ALA D 1 218 ? 165.026 136.387 102.159 1.00 29.46  ? 218 ALA D O   1 
ATOM   15831 C CB  . ALA D 1 218 ? 168.220 135.336 101.966 1.00 27.04  ? 218 ALA D CB  1 
ATOM   15832 N N   . CYS D 1 219 ? 166.496 137.694 103.210 1.00 28.54  ? 219 CYS D N   1 
ATOM   15833 C CA  . CYS D 1 219 ? 165.540 138.190 104.200 1.00 28.74  ? 219 CYS D CA  1 
ATOM   15834 C C   . CYS D 1 219 ? 164.441 139.079 103.601 1.00 33.23  ? 219 CYS D C   1 
ATOM   15835 O O   . CYS D 1 219 ? 163.335 139.137 104.130 1.00 32.12  ? 219 CYS D O   1 
ATOM   15836 C CB  . CYS D 1 219 ? 166.279 138.907 105.339 1.00 32.38  ? 219 CYS D CB  1 
ATOM   15837 S SG  . CYS D 1 219 ? 167.388 137.784 106.259 1.00 36.50  ? 219 CYS D SG  1 
ATOM   15838 N N   . THR D 1 220 ? 164.717 139.629 102.411 1.00 40.44  ? 220 THR D N   1 
ATOM   15839 C CA  . THR D 1 220 ? 163.708 140.452 101.691 1.00 33.81  ? 220 THR D CA  1 
ATOM   15840 C C   . THR D 1 220 ? 162.941 139.580 100.686 1.00 38.69  ? 220 THR D C   1 
ATOM   15841 O O   . THR D 1 220 ? 161.960 140.099 100.122 1.00 48.03  ? 220 THR D O   1 
ATOM   15842 C CB  . THR D 1 220 ? 164.375 141.638 100.982 1.00 38.80  ? 220 THR D CB  1 
ATOM   15843 O OG1 . THR D 1 220 ? 165.322 141.111 100.052 1.00 43.27  ? 220 THR D OG1 1 
ATOM   15844 C CG2 . THR D 1 220 ? 165.068 142.582 101.940 1.00 37.39  ? 220 THR D CG2 1 
ATOM   15845 N N   . LYS D 1 221 ? 163.390 138.341 100.439 1.00 41.73  ? 221 LYS D N   1 
ATOM   15846 C CA  . LYS D 1 221 ? 162.676 137.375 99.541  1.00 40.12  ? 221 LYS D CA  1 
ATOM   15847 C C   . LYS D 1 221 ? 162.965 137.670 98.057  1.00 43.09  ? 221 LYS D C   1 
ATOM   15848 O O   . LYS D 1 221 ? 162.126 137.306 97.209  1.00 43.36  ? 221 LYS D O   1 
ATOM   15849 C CB  . LYS D 1 221 ? 161.180 137.314 99.882  1.00 37.84  ? 221 LYS D CB  1 
ATOM   15850 C CG  . LYS D 1 221 ? 160.238 138.153 99.027  1.00 44.63  ? 221 LYS D CG  1 
ATOM   15851 C CD  . LYS D 1 221 ? 158.780 137.927 99.358  1.00 45.46  ? 221 LYS D CD  1 
ATOM   15852 C CE  . LYS D 1 221 ? 157.841 138.460 98.297  1.00 49.55  ? 221 LYS D CE  1 
ATOM   15853 N NZ  . LYS D 1 221 ? 156.421 138.276 98.679  1.00 50.93  ? 221 LYS D NZ  1 
ATOM   15854 N N   . GLN D 1 222 ? 164.126 138.250 97.744  1.00 44.99  ? 222 GLN D N   1 
ATOM   15855 C CA  . GLN D 1 222 ? 164.514 138.528 96.360  1.00 43.83  ? 222 GLN D CA  1 
ATOM   15856 C C   . GLN D 1 222 ? 165.269 137.342 95.760  1.00 40.13  ? 222 GLN D C   1 
ATOM   15857 O O   . GLN D 1 222 ? 166.488 137.365 95.612  1.00 41.93  ? 222 GLN D O   1 
ATOM   15858 C CB  . GLN D 1 222 ? 165.323 139.824 96.295  1.00 45.16  ? 222 GLN D CB  1 
ATOM   15859 C CG  . GLN D 1 222 ? 164.416 141.020 96.579  1.00 38.59  ? 222 GLN D CG  1 
ATOM   15860 C CD  . GLN D 1 222 ? 165.206 142.246 96.976  1.00 40.34  ? 222 GLN D CD  1 
ATOM   15861 O OE1 . GLN D 1 222 ? 165.024 142.799 98.042  1.00 47.11  ? 222 GLN D OE1 1 
ATOM   15862 N NE2 . GLN D 1 222 ? 166.116 142.714 96.164  1.00 45.84  ? 222 GLN D NE2 1 
ATOM   15863 N N   . TRP D 1 223 ? 164.544 136.277 95.436  1.00 41.89  ? 223 TRP D N   1 
ATOM   15864 C CA  . TRP D 1 223 ? 165.140 135.018 94.989  1.00 50.21  ? 223 TRP D CA  1 
ATOM   15865 C C   . TRP D 1 223 ? 165.951 135.147 93.688  1.00 50.27  ? 223 TRP D C   1 
ATOM   15866 O O   . TRP D 1 223 ? 166.966 134.484 93.521  1.00 50.28  ? 223 TRP D O   1 
ATOM   15867 C CB  . TRP D 1 223 ? 164.021 133.977 94.881  1.00 47.55  ? 223 TRP D CB  1 
ATOM   15868 C CG  . TRP D 1 223 ? 164.499 132.595 94.590  1.00 48.26  ? 223 TRP D CG  1 
ATOM   15869 C CD1 . TRP D 1 223 ? 164.162 131.846 93.516  1.00 50.98  ? 223 TRP D CD1 1 
ATOM   15870 C CD2 . TRP D 1 223 ? 165.417 131.781 95.377  1.00 51.71  ? 223 TRP D CD2 1 
ATOM   15871 N NE1 . TRP D 1 223 ? 164.814 130.630 93.583  1.00 52.41  ? 223 TRP D NE1 1 
ATOM   15872 C CE2 . TRP D 1 223 ? 165.614 130.542 94.701  1.00 53.70  ? 223 TRP D CE2 1 
ATOM   15873 C CE3 . TRP D 1 223 ? 166.119 131.972 96.585  1.00 48.93  ? 223 TRP D CE3 1 
ATOM   15874 C CZ2 . TRP D 1 223 ? 166.477 129.557 95.188  1.00 48.71  ? 223 TRP D CZ2 1 
ATOM   15875 C CZ3 . TRP D 1 223 ? 167.010 131.000 97.071  1.00 44.18  ? 223 TRP D CZ3 1 
ATOM   15876 C CH2 . TRP D 1 223 ? 167.215 129.814 96.353  1.00 50.56  ? 223 TRP D CH2 1 
ATOM   15877 N N   . ASP D 1 224 ? 165.561 136.063 92.801  1.00 50.09  ? 224 ASP D N   1 
ATOM   15878 C CA  . ASP D 1 224 ? 166.310 136.416 91.552  1.00 49.31  ? 224 ASP D CA  1 
ATOM   15879 C C   . ASP D 1 224 ? 167.583 137.229 91.856  1.00 49.15  ? 224 ASP D C   1 
ATOM   15880 O O   . ASP D 1 224 ? 168.523 137.115 91.046  1.00 48.67  ? 224 ASP D O   1 
ATOM   15881 C CB  . ASP D 1 224 ? 165.416 137.179 90.571  1.00 51.64  ? 224 ASP D CB  1 
ATOM   15882 C CG  . ASP D 1 224 ? 164.934 138.514 91.114  1.00 56.26  ? 224 ASP D CG  1 
ATOM   15883 O OD1 . ASP D 1 224 ? 165.167 138.776 92.311  1.00 54.71  ? 224 ASP D OD1 1 
ATOM   15884 O OD2 . ASP D 1 224 ? 164.335 139.280 90.335  1.00 57.67  ? 224 ASP D OD2 1 
ATOM   15885 N N   . VAL D 1 225 ? 167.655 137.998 92.946  1.00 48.37  ? 225 VAL D N   1 
ATOM   15886 C CA  . VAL D 1 225 ? 168.905 138.616 93.407  1.00 45.62  ? 225 VAL D CA  1 
ATOM   15887 C C   . VAL D 1 225 ? 169.799 137.588 94.101  1.00 48.98  ? 225 VAL D C   1 
ATOM   15888 O O   . VAL D 1 225 ? 171.004 137.588 93.876  1.00 48.56  ? 225 VAL D O   1 
ATOM   15889 C CB  . VAL D 1 225 ? 168.635 139.822 94.325  1.00 46.89  ? 225 VAL D CB  1 
ATOM   15890 C CG1 . VAL D 1 225 ? 169.924 140.415 94.888  1.00 46.82  ? 225 VAL D CG1 1 
ATOM   15891 C CG2 . VAL D 1 225 ? 167.917 140.945 93.573  1.00 45.09  ? 225 VAL D CG2 1 
ATOM   15892 N N   . VAL D 1 226 ? 169.230 136.682 94.901  1.00 47.35  ? 226 VAL D N   1 
ATOM   15893 C CA  . VAL D 1 226 ? 169.963 135.590 95.554  1.00 46.28  ? 226 VAL D CA  1 
ATOM   15894 C C   . VAL D 1 226 ? 170.692 134.715 94.532  1.00 45.28  ? 226 VAL D C   1 
ATOM   15895 O O   . VAL D 1 226 ? 171.904 134.542 94.639  1.00 46.38  ? 226 VAL D O   1 
ATOM   15896 C CB  . VAL D 1 226 ? 169.014 134.760 96.440  1.00 44.68  ? 226 VAL D CB  1 
ATOM   15897 C CG1 . VAL D 1 226 ? 169.614 133.435 96.902  1.00 47.51  ? 226 VAL D CG1 1 
ATOM   15898 C CG2 . VAL D 1 226 ? 168.610 135.540 97.688  1.00 41.76  ? 226 VAL D CG2 1 
ATOM   15899 N N   . THR D 1 227 ? 169.991 134.208 93.512  1.00 51.29  ? 227 THR D N   1 
ATOM   15900 C CA  . THR D 1 227 ? 170.639 133.396 92.474  1.00 51.12  ? 227 THR D CA  1 
ATOM   15901 C C   . THR D 1 227 ? 171.672 134.190 91.685  1.00 50.49  ? 227 THR D C   1 
ATOM   15902 O O   . THR D 1 227 ? 172.740 133.661 91.410  1.00 54.87  ? 227 THR D O   1 
ATOM   15903 C CB  . THR D 1 227 ? 169.640 132.742 91.514  1.00 53.14  ? 227 THR D CB  1 
ATOM   15904 O OG1 . THR D 1 227 ? 168.845 133.708 90.884  1.00 55.88  ? 227 THR D OG1 1 
ATOM   15905 C CG2 . THR D 1 227 ? 168.735 131.756 92.236  1.00 51.72  ? 227 THR D CG2 1 
ATOM   15906 N N   . TYR D 1 228 ? 171.441 135.467 91.376  1.00 48.60  ? 228 TYR D N   1 
ATOM   15907 C CA  . TYR D 1 228 ? 172.461 136.310 90.757  1.00 46.01  ? 228 TYR D CA  1 
ATOM   15908 C C   . TYR D 1 228 ? 173.700 136.487 91.644  1.00 46.16  ? 228 TYR D C   1 
ATOM   15909 O O   . TYR D 1 228 ? 174.822 136.237 91.203  1.00 49.22  ? 228 TYR D O   1 
ATOM   15910 C CB  . TYR D 1 228 ? 171.944 137.698 90.375  1.00 50.00  ? 228 TYR D CB  1 
ATOM   15911 C CG  . TYR D 1 228 ? 173.050 138.594 89.882  1.00 54.69  ? 228 TYR D CG  1 
ATOM   15912 C CD1 . TYR D 1 228 ? 173.498 138.530 88.573  1.00 52.37  ? 228 TYR D CD1 1 
ATOM   15913 C CD2 . TYR D 1 228 ? 173.703 139.457 90.745  1.00 50.90  ? 228 TYR D CD2 1 
ATOM   15914 C CE1 . TYR D 1 228 ? 174.542 139.323 88.127  1.00 48.91  ? 228 TYR D CE1 1 
ATOM   15915 C CE2 . TYR D 1 228 ? 174.746 140.258 90.317  1.00 45.62  ? 228 TYR D CE2 1 
ATOM   15916 C CZ  . TYR D 1 228 ? 175.168 140.190 89.004  1.00 51.33  ? 228 TYR D CZ  1 
ATOM   15917 O OH  . TYR D 1 228 ? 176.197 140.975 88.581  1.00 56.03  ? 228 TYR D OH  1 
ATOM   15918 N N   . LEU D 1 229 ? 173.538 136.873 92.909  1.00 50.38  ? 229 LEU D N   1 
ATOM   15919 C CA  . LEU D 1 229 ? 174.662 137.051 93.827  1.00 49.19  ? 229 LEU D CA  1 
ATOM   15920 C C   . LEU D 1 229 ? 175.459 135.756 93.999  1.00 54.21  ? 229 LEU D C   1 
ATOM   15921 O O   . LEU D 1 229 ? 176.677 135.820 94.071  1.00 54.88  ? 229 LEU D O   1 
ATOM   15922 C CB  . LEU D 1 229 ? 174.174 137.556 95.193  1.00 48.81  ? 229 LEU D CB  1 
ATOM   15923 C CG  . LEU D 1 229 ? 173.662 139.006 95.234  1.00 52.30  ? 229 LEU D CG  1 
ATOM   15924 C CD1 . LEU D 1 229 ? 173.247 139.333 96.665  1.00 46.38  ? 229 LEU D CD1 1 
ATOM   15925 C CD2 . LEU D 1 229 ? 174.703 140.032 94.785  1.00 51.42  ? 229 LEU D CD2 1 
ATOM   15926 N N   . LEU D 1 230 ? 174.802 134.598 94.029  1.00 52.98  ? 230 LEU D N   1 
ATOM   15927 C CA  . LEU D 1 230 ? 175.445 133.290 94.114  1.00 50.07  ? 230 LEU D CA  1 
ATOM   15928 C C   . LEU D 1 230 ? 176.128 132.846 92.807  1.00 53.51  ? 230 LEU D C   1 
ATOM   15929 O O   . LEU D 1 230 ? 177.250 132.348 92.848  1.00 56.90  ? 230 LEU D O   1 
ATOM   15930 C CB  . LEU D 1 230 ? 174.383 132.268 94.545  1.00 51.46  ? 230 LEU D CB  1 
ATOM   15931 C CG  . LEU D 1 230 ? 173.922 132.385 96.008  1.00 46.94  ? 230 LEU D CG  1 
ATOM   15932 C CD1 . LEU D 1 230 ? 172.729 131.469 96.260  1.00 46.96  ? 230 LEU D CD1 1 
ATOM   15933 C CD2 . LEU D 1 230 ? 175.021 131.991 96.982  1.00 45.33  ? 230 LEU D CD2 1 
ATOM   15934 N N   . GLU D 1 231 ? 175.475 132.991 91.656  1.00 59.08  ? 231 GLU D N   1 
ATOM   15935 C CA  . GLU D 1 231 ? 175.890 132.365 90.392  1.00 57.35  ? 231 GLU D CA  1 
ATOM   15936 C C   . GLU D 1 231 ? 176.636 133.283 89.407  1.00 60.43  ? 231 GLU D C   1 
ATOM   15937 O O   . GLU D 1 231 ? 177.127 132.788 88.389  1.00 66.58  ? 231 GLU D O   1 
ATOM   15938 C CB  . GLU D 1 231 ? 174.673 131.723 89.708  1.00 58.53  ? 231 GLU D CB  1 
ATOM   15939 C CG  . GLU D 1 231 ? 174.025 130.634 90.572  1.00 60.62  ? 231 GLU D CG  1 
ATOM   15940 C CD  . GLU D 1 231 ? 172.989 129.821 89.792  1.00 61.83  ? 231 GLU D CD  1 
ATOM   15941 O OE1 . GLU D 1 231 ? 172.104 130.413 89.136  1.00 62.92  ? 231 GLU D OE1 1 
ATOM   15942 O OE2 . GLU D 1 231 ? 173.054 128.572 89.836  1.00 63.22  ? 231 GLU D OE2 1 
ATOM   15943 N N   . ASN D 1 232 ? 176.737 134.594 89.650  1.00 57.16  ? 232 ASN D N   1 
ATOM   15944 C CA  . ASN D 1 232 ? 177.439 135.503 88.738  1.00 59.33  ? 232 ASN D CA  1 
ATOM   15945 C C   . ASN D 1 232 ? 178.954 135.193 88.627  1.00 60.58  ? 232 ASN D C   1 
ATOM   15946 O O   . ASN D 1 232 ? 179.549 134.672 89.574  1.00 60.33  ? 232 ASN D O   1 
ATOM   15947 C CB  . ASN D 1 232 ? 177.192 136.969 89.137  1.00 58.36  ? 232 ASN D CB  1 
ATOM   15948 C CG  . ASN D 1 232 ? 178.060 137.431 90.289  1.00 59.93  ? 232 ASN D CG  1 
ATOM   15949 O OD1 . ASN D 1 232 ? 179.182 137.867 90.096  1.00 60.95  ? 232 ASN D OD1 1 
ATOM   15950 N ND2 . ASN D 1 232 ? 177.585 137.341 91.502  1.00 54.49  ? 232 ASN D ND2 1 
ATOM   15951 N N   . PRO D 1 233 ? 179.608 135.537 87.501  1.00 62.00  ? 233 PRO D N   1 
ATOM   15952 C CA  . PRO D 1 233 ? 181.030 135.267 87.292  1.00 61.49  ? 233 PRO D CA  1 
ATOM   15953 C C   . PRO D 1 233 ? 181.983 136.303 87.921  1.00 63.66  ? 233 PRO D C   1 
ATOM   15954 O O   . PRO D 1 233 ? 183.166 136.014 88.085  1.00 63.41  ? 233 PRO D O   1 
ATOM   15955 C CB  . PRO D 1 233 ? 181.187 135.239 85.774  1.00 60.40  ? 233 PRO D CB  1 
ATOM   15956 C CG  . PRO D 1 233 ? 180.155 136.254 85.294  1.00 61.39  ? 233 PRO D CG  1 
ATOM   15957 C CD  . PRO D 1 233 ? 179.008 136.053 86.279  1.00 59.44  ? 233 PRO D CD  1 
ATOM   15958 N N   . HIS D 1 234 ? 181.519 137.513 88.236  1.00 64.62  ? 234 HIS D N   1 
ATOM   15959 C CA  . HIS D 1 234 ? 182.366 138.651 88.632  1.00 64.80  ? 234 HIS D CA  1 
ATOM   15960 C C   . HIS D 1 234 ? 182.864 138.529 90.073  1.00 63.52  ? 234 HIS D C   1 
ATOM   15961 O O   . HIS D 1 234 ? 184.084 138.646 90.292  1.00 63.23  ? 234 HIS D O   1 
ATOM   15962 C CB  . HIS D 1 234 ? 181.593 139.963 88.435  1.00 63.55  ? 234 HIS D CB  1 
ATOM   15963 C CG  . HIS D 1 234 ? 180.402 139.823 87.548  1.00 65.40  ? 234 HIS D CG  1 
ATOM   15964 N ND1 . HIS D 1 234 ? 180.512 139.716 86.176  1.00 65.39  ? 234 HIS D ND1 1 
ATOM   15965 C CD2 . HIS D 1 234 ? 179.082 139.771 87.827  1.00 65.37  ? 234 HIS D CD2 1 
ATOM   15966 C CE1 . HIS D 1 234 ? 179.310 139.606 85.648  1.00 65.63  ? 234 HIS D CE1 1 
ATOM   15967 N NE2 . HIS D 1 234 ? 178.415 139.634 86.641  1.00 65.51  ? 234 HIS D NE2 1 
ATOM   15968 N N   . GLN D 1 235 ? 181.941 138.292 91.002  1.00 64.12  ? 235 GLN D N   1 
ATOM   15969 C CA  . GLN D 1 235 ? 182.223 137.885 92.375  1.00 62.88  ? 235 GLN D CA  1 
ATOM   15970 C C   . GLN D 1 235 ? 180.998 137.140 92.923  1.00 63.19  ? 235 GLN D C   1 
ATOM   15971 O O   . GLN D 1 235 ? 179.976 137.776 93.200  1.00 60.94  ? 235 GLN D O   1 
ATOM   15972 C CB  . GLN D 1 235 ? 182.591 139.093 93.256  1.00 59.15  ? 235 GLN D CB  1 
ATOM   15973 C CG  . GLN D 1 235 ? 182.911 138.643 94.690  1.00 61.24  ? 235 GLN D CG  1 
ATOM   15974 C CD  . GLN D 1 235 ? 183.355 139.772 95.615  1.00 64.73  ? 235 GLN D CD  1 
ATOM   15975 O OE1 . GLN D 1 235 ? 183.978 140.743 95.219  1.00 64.60  ? 235 GLN D OE1 1 
ATOM   15976 N NE2 . GLN D 1 235 ? 183.047 139.673 96.891  1.00 64.37  ? 235 GLN D NE2 1 
ATOM   15977 N N   . PRO D 1 236 ? 181.064 135.812 93.109  1.00 64.19  ? 236 PRO D N   1 
ATOM   15978 C CA  . PRO D 1 236 ? 179.978 135.067 93.725  1.00 58.92  ? 236 PRO D CA  1 
ATOM   15979 C C   . PRO D 1 236 ? 179.951 135.277 95.244  1.00 57.63  ? 236 PRO D C   1 
ATOM   15980 O O   . PRO D 1 236 ? 180.988 135.270 95.910  1.00 57.68  ? 236 PRO D O   1 
ATOM   15981 C CB  . PRO D 1 236 ? 180.230 133.612 93.333  1.00 57.66  ? 236 PRO D CB  1 
ATOM   15982 C CG  . PRO D 1 236 ? 181.749 133.537 93.214  1.00 59.47  ? 236 PRO D CG  1 
ATOM   15983 C CD  . PRO D 1 236 ? 182.135 134.919 92.697  1.00 58.85  ? 236 PRO D CD  1 
ATOM   15984 N N   . ALA D 1 237 ? 178.760 135.416 95.813  1.00 53.18  ? 237 ALA D N   1 
ATOM   15985 C CA  . ALA D 1 237 ? 178.517 135.263 97.238  1.00 52.62  ? 237 ALA D CA  1 
ATOM   15986 C C   . ALA D 1 237 ? 178.752 133.803 97.663  1.00 54.60  ? 237 ALA D C   1 
ATOM   15987 O O   . ALA D 1 237 ? 178.500 132.874 96.894  1.00 56.16  ? 237 ALA D O   1 
ATOM   15988 C CB  . ALA D 1 237 ? 177.087 135.692 97.558  1.00 51.41  ? 237 ALA D CB  1 
ATOM   15989 N N   . SER D 1 238 ? 179.193 133.587 98.899  1.00 44.30  ? 238 SER D N   1 
ATOM   15990 C CA  . SER D 1 238 ? 179.279 132.257 99.492  1.00 46.74  ? 238 SER D CA  1 
ATOM   15991 C C   . SER D 1 238 ? 178.198 132.093 100.555 1.00 46.04  ? 238 SER D C   1 
ATOM   15992 O O   . SER D 1 238 ? 177.998 132.957 101.405 1.00 49.21  ? 238 SER D O   1 
ATOM   15993 C CB  . SER D 1 238 ? 180.688 131.950 100.004 1.00 48.04  ? 238 SER D CB  1 
ATOM   15994 O OG  . SER D 1 238 ? 181.112 132.851 100.999 1.00 48.60  ? 238 SER D OG  1 
ATOM   15995 N N   . LEU D 1 239 ? 177.510 130.952 100.526 1.00 42.88  ? 239 LEU D N   1 
ATOM   15996 C CA  . LEU D 1 239 ? 176.526 130.577 101.546 1.00 42.11  ? 239 LEU D CA  1 
ATOM   15997 C C   . LEU D 1 239 ? 177.185 130.387 102.922 1.00 43.31  ? 239 LEU D C   1 
ATOM   15998 O O   . LEU D 1 239 ? 176.531 130.511 103.952 1.00 44.60  ? 239 LEU D O   1 
ATOM   15999 C CB  . LEU D 1 239 ? 175.811 129.297 101.081 1.00 38.98  ? 239 LEU D CB  1 
ATOM   16000 C CG  . LEU D 1 239 ? 174.936 129.526 99.839  1.00 42.76  ? 239 LEU D CG  1 
ATOM   16001 C CD1 . LEU D 1 239 ? 174.658 128.237 99.095  1.00 43.81  ? 239 LEU D CD1 1 
ATOM   16002 C CD2 . LEU D 1 239 ? 173.601 130.139 100.218 1.00 41.72  ? 239 LEU D CD2 1 
ATOM   16003 N N   . GLU D 1 240 ? 178.492 130.134 102.933 1.00 44.40  ? 240 GLU D N   1 
ATOM   16004 C CA  . GLU D 1 240 ? 179.338 130.006 104.116 1.00 42.92  ? 240 GLU D CA  1 
ATOM   16005 C C   . GLU D 1 240 ? 179.650 131.331 104.818 1.00 44.65  ? 240 GLU D C   1 
ATOM   16006 O O   . GLU D 1 240 ? 180.128 131.304 105.948 1.00 50.87  ? 240 GLU D O   1 
ATOM   16007 C CB  . GLU D 1 240 ? 180.690 129.407 103.711 1.00 45.86  ? 240 GLU D CB  1 
ATOM   16008 C CG  . GLU D 1 240 ? 180.621 128.072 102.975 1.00 46.07  ? 240 GLU D CG  1 
ATOM   16009 C CD  . GLU D 1 240 ? 182.041 127.556 102.716 1.00 52.24  ? 240 GLU D CD  1 
ATOM   16010 O OE1 . GLU D 1 240 ? 182.758 127.233 103.687 1.00 50.19  ? 240 GLU D OE1 1 
ATOM   16011 O OE2 . GLU D 1 240 ? 182.461 127.516 101.538 1.00 54.52  ? 240 GLU D OE2 1 
ATOM   16012 N N   . ALA D 1 241 ? 179.465 132.482 104.169 1.00 42.09  ? 241 ALA D N   1 
ATOM   16013 C CA  . ALA D 1 241 ? 179.876 133.771 104.722 1.00 39.61  ? 241 ALA D CA  1 
ATOM   16014 C C   . ALA D 1 241 ? 179.073 134.146 105.977 1.00 36.97  ? 241 ALA D C   1 
ATOM   16015 O O   . ALA D 1 241 ? 177.859 133.955 106.036 1.00 39.55  ? 241 ALA D O   1 
ATOM   16016 C CB  . ALA D 1 241 ? 179.768 134.847 103.643 1.00 41.33  ? 241 ALA D CB  1 
ATOM   16017 N N   . THR D 1 242 ? 179.750 134.713 106.974 1.00 37.09  ? 242 THR D N   1 
ATOM   16018 C CA  . THR D 1 242 ? 179.181 135.011 108.298 1.00 38.69  ? 242 THR D CA  1 
ATOM   16019 C C   . THR D 1 242 ? 179.259 136.487 108.676 1.00 36.50  ? 242 THR D C   1 
ATOM   16020 O O   . THR D 1 242 ? 180.166 137.215 108.266 1.00 41.05  ? 242 THR D O   1 
ATOM   16021 C CB  . THR D 1 242 ? 179.815 134.163 109.409 1.00 39.06  ? 242 THR D CB  1 
ATOM   16022 O OG1 . THR D 1 242 ? 181.207 134.346 109.452 1.00 44.88  ? 242 THR D OG1 1 
ATOM   16023 C CG2 . THR D 1 242 ? 179.534 132.676 109.257 1.00 34.83  ? 242 THR D CG2 1 
ATOM   16024 N N   . ASP D 1 243 ? 178.282 136.938 109.463 1.00 34.90  ? 243 ASP D N   1 
ATOM   16025 C CA  . ASP D 1 243 ? 178.297 138.337 109.979 1.00 31.94  ? 243 ASP D CA  1 
ATOM   16026 C C   . ASP D 1 243 ? 179.025 138.455 111.332 1.00 37.80  ? 243 ASP D C   1 
ATOM   16027 O O   . ASP D 1 243 ? 179.671 137.470 111.740 1.00 46.01  ? 243 ASP D O   1 
ATOM   16028 C CB  . ASP D 1 243 ? 176.874 138.888 110.102 1.00 33.87  ? 243 ASP D CB  1 
ATOM   16029 C CG  . ASP D 1 243 ? 176.068 138.235 111.212 1.00 38.18  ? 243 ASP D CG  1 
ATOM   16030 O OD1 . ASP D 1 243 ? 176.631 137.367 111.909 1.00 42.62  ? 243 ASP D OD1 1 
ATOM   16031 O OD2 . ASP D 1 243 ? 174.888 138.602 111.371 1.00 42.72  ? 243 ASP D OD2 1 
ATOM   16032 N N   . SER D 1 244 ? 178.917 139.610 111.994 1.00 40.28  ? 244 SER D N   1 
ATOM   16033 C CA  . SER D 1 244 ? 179.609 139.906 113.258 1.00 40.03  ? 244 SER D CA  1 
ATOM   16034 C C   . SER D 1 244 ? 179.176 139.054 114.463 1.00 42.75  ? 244 SER D C   1 
ATOM   16035 O O   . SER D 1 244 ? 179.871 139.058 115.475 1.00 47.88  ? 244 SER D O   1 
ATOM   16036 C CB  . SER D 1 244 ? 179.427 141.380 113.622 1.00 44.79  ? 244 SER D CB  1 
ATOM   16037 O OG  . SER D 1 244 ? 179.806 142.223 112.553 1.00 49.99  ? 244 SER D OG  1 
ATOM   16038 N N   . LEU D 1 245 ? 178.056 138.330 114.384 1.00 43.98  ? 245 LEU D N   1 
ATOM   16039 C CA  . LEU D 1 245 ? 177.614 137.318 115.358 1.00 35.77  ? 245 LEU D CA  1 
ATOM   16040 C C   . LEU D 1 245 ? 178.026 135.896 114.946 1.00 36.71  ? 245 LEU D C   1 
ATOM   16041 O O   . LEU D 1 245 ? 177.723 134.935 115.650 1.00 38.00  ? 245 LEU D O   1 
ATOM   16042 C CB  . LEU D 1 245 ? 176.086 137.379 115.527 1.00 37.06  ? 245 LEU D CB  1 
ATOM   16043 C CG  . LEU D 1 245 ? 175.525 138.688 116.094 1.00 39.58  ? 245 LEU D CG  1 
ATOM   16044 C CD1 . LEU D 1 245 ? 174.001 138.641 116.077 1.00 40.08  ? 245 LEU D CD1 1 
ATOM   16045 C CD2 . LEU D 1 245 ? 175.972 138.919 117.534 1.00 36.18  ? 245 LEU D CD2 1 
ATOM   16046 N N   . GLY D 1 246 ? 178.679 135.733 113.795 1.00 33.08  ? 246 GLY D N   1 
ATOM   16047 C CA  . GLY D 1 246 ? 178.981 134.448 113.181 1.00 25.62  ? 246 GLY D CA  1 
ATOM   16048 C C   . GLY D 1 246 ? 177.793 133.818 112.449 1.00 34.06  ? 246 GLY D C   1 
ATOM   16049 O O   . GLY D 1 246 ? 177.872 132.659 112.067 1.00 39.09  ? 246 GLY D O   1 
ATOM   16050 N N   . ASN D 1 247 ? 176.685 134.531 112.260 1.00 33.88  ? 247 ASN D N   1 
ATOM   16051 C CA  . ASN D 1 247 ? 175.503 134.005 111.589 1.00 25.19  ? 247 ASN D CA  1 
ATOM   16052 C C   . ASN D 1 247 ? 175.703 133.932 110.070 1.00 29.26  ? 247 ASN D C   1 
ATOM   16053 O O   . ASN D 1 247 ? 176.082 134.917 109.443 1.00 38.12  ? 247 ASN D O   1 
ATOM   16054 C CB  . ASN D 1 247 ? 174.285 134.865 111.967 1.00 24.05  ? 247 ASN D CB  1 
ATOM   16055 C CG  . ASN D 1 247 ? 173.801 134.649 113.383 1.00 26.15  ? 247 ASN D CG  1 
ATOM   16056 O OD1 . ASN D 1 247 ? 174.126 133.684 114.044 1.00 27.63  ? 247 ASN D OD1 1 
ATOM   16057 N ND2 . ASN D 1 247 ? 172.963 135.507 113.891 1.00 31.94  ? 247 ASN D ND2 1 
ATOM   16058 N N   . THR D 1 248 ? 175.417 132.776 109.475 1.00 30.79  ? 248 THR D N   1 
ATOM   16059 C CA  . THR D 1 248 ? 175.249 132.612 108.022 1.00 27.78  ? 248 THR D CA  1 
ATOM   16060 C C   . THR D 1 248 ? 173.883 133.132 107.567 1.00 20.28  ? 248 THR D C   1 
ATOM   16061 O O   . THR D 1 248 ? 173.042 133.506 108.380 1.00 33.21  ? 248 THR D O   1 
ATOM   16062 C CB  . THR D 1 248 ? 175.394 131.143 107.593 1.00 30.34  ? 248 THR D CB  1 
ATOM   16063 O OG1 . THR D 1 248 ? 174.314 130.366 108.066 1.00 34.73  ? 248 THR D OG1 1 
ATOM   16064 C CG2 . THR D 1 248 ? 176.699 130.493 108.031 1.00 27.88  ? 248 THR D CG2 1 
ATOM   16065 N N   . VAL D 1 249 ? 173.599 133.105 106.266 1.00 20.48  ? 249 VAL D N   1 
ATOM   16066 C CA  . VAL D 1 249 ? 172.252 133.399 105.752 1.00 24.97  ? 249 VAL D CA  1 
ATOM   16067 C C   . VAL D 1 249 ? 171.171 132.459 106.313 1.00 21.26  ? 249 VAL D C   1 
ATOM   16068 O O   . VAL D 1 249 ? 170.041 132.887 106.521 1.00 22.01  ? 249 VAL D O   1 
ATOM   16069 C CB  . VAL D 1 249 ? 172.268 133.428 104.214 1.00 25.94  ? 249 VAL D CB  1 
ATOM   16070 C CG1 . VAL D 1 249 ? 172.685 132.101 103.579 1.00 21.65  ? 249 VAL D CG1 1 
ATOM   16071 C CG2 . VAL D 1 249 ? 170.911 133.840 103.655 1.00 24.17  ? 249 VAL D CG2 1 
ATOM   16072 N N   . LEU D 1 250 ? 171.493 131.204 106.645 1.00 29.96  ? 250 LEU D N   1 
ATOM   16073 C CA  . LEU D 1 250 ? 170.537 130.271 107.252 1.00 23.13  ? 250 LEU D CA  1 
ATOM   16074 C C   . LEU D 1 250 ? 170.246 130.606 108.716 1.00 24.29  ? 250 LEU D C   1 
ATOM   16075 O O   . LEU D 1 250 ? 169.103 130.503 109.152 1.00 27.98  ? 250 LEU D O   1 
ATOM   16076 C CB  . LEU D 1 250 ? 171.041 128.827 107.122 1.00 21.02  ? 250 LEU D CB  1 
ATOM   16077 C CG  . LEU D 1 250 ? 171.194 128.303 105.688 1.00 25.33  ? 250 LEU D CG  1 
ATOM   16078 C CD1 . LEU D 1 250 ? 171.643 126.845 105.749 1.00 30.18  ? 250 LEU D CD1 1 
ATOM   16079 C CD2 . LEU D 1 250 ? 169.903 128.362 104.876 1.00 20.23  ? 250 LEU D CD2 1 
ATOM   16080 N N   . HIS D 1 251 ? 171.239 131.076 109.469 1.00 27.71  ? 251 HIS D N   1 
ATOM   16081 C CA  . HIS D 1 251 ? 171.021 131.646 110.799 1.00 15.90  ? 251 HIS D CA  1 
ATOM   16082 C C   . HIS D 1 251 ? 170.208 132.939 110.739 1.00 23.68  ? 251 HIS D C   1 
ATOM   16083 O O   . HIS D 1 251 ? 169.293 133.088 111.572 1.00 31.90  ? 251 HIS D O   1 
ATOM   16084 C CB  . HIS D 1 251 ? 172.367 131.916 111.488 1.00 19.81  ? 251 HIS D CB  1 
ATOM   16085 C CG  . HIS D 1 251 ? 173.168 130.693 111.789 1.00 18.53  ? 251 HIS D CG  1 
ATOM   16086 N ND1 . HIS D 1 251 ? 174.156 130.232 110.940 1.00 20.49  ? 251 HIS D ND1 1 
ATOM   16087 C CD2 . HIS D 1 251 ? 173.143 129.846 112.841 1.00 23.02  ? 251 HIS D CD2 1 
ATOM   16088 C CE1 . HIS D 1 251 ? 174.701 129.148 111.454 1.00 27.82  ? 251 HIS D CE1 1 
ATOM   16089 N NE2 . HIS D 1 251 ? 174.097 128.892 112.621 1.00 34.92  ? 251 HIS D NE2 1 
ATOM   16090 N N   . ALA D 1 252 ? 170.511 133.832 109.796 1.00 28.18  ? 252 ALA D N   1 
ATOM   16091 C CA  . ALA D 1 252 ? 169.762 135.061 109.578 1.00 11.95  ? 252 ALA D CA  1 
ATOM   16092 C C   . ALA D 1 252 ? 168.286 134.795 109.242 1.00 15.52  ? 252 ALA D C   1 
ATOM   16093 O O   . ALA D 1 252 ? 167.417 135.466 109.781 1.00 26.86  ? 252 ALA D O   1 
ATOM   16094 C CB  . ALA D 1 252 ? 170.456 135.873 108.488 1.00 18.76  ? 252 ALA D CB  1 
ATOM   16095 N N   . LEU D 1 253 ? 167.968 133.787 108.439 1.00 23.12  ? 253 LEU D N   1 
ATOM   16096 C CA  . LEU D 1 253 ? 166.585 133.393 108.173 1.00 20.48  ? 253 LEU D CA  1 
ATOM   16097 C C   . LEU D 1 253 ? 165.840 132.922 109.425 1.00 25.50  ? 253 LEU D C   1 
ATOM   16098 O O   . LEU D 1 253 ? 164.699 133.308 109.643 1.00 35.87  ? 253 LEU D O   1 
ATOM   16099 C CB  . LEU D 1 253 ? 166.589 132.311 107.089 1.00 22.31  ? 253 LEU D CB  1 
ATOM   16100 C CG  . LEU D 1 253 ? 166.669 132.916 105.685 1.00 27.24  ? 253 LEU D CG  1 
ATOM   16101 C CD1 . LEU D 1 253 ? 167.103 131.856 104.696 1.00 29.89  ? 253 LEU D CD1 1 
ATOM   16102 C CD2 . LEU D 1 253 ? 165.303 133.422 105.239 1.00 28.53  ? 253 LEU D CD2 1 
ATOM   16103 N N   . VAL D 1 254 ? 166.489 132.146 110.291 1.00 23.38  ? 254 VAL D N   1 
ATOM   16104 C CA  . VAL D 1 254 ? 165.946 131.797 111.609 1.00 19.83  ? 254 VAL D CA  1 
ATOM   16105 C C   . VAL D 1 254 ? 165.733 133.047 112.475 1.00 26.60  ? 254 VAL D C   1 
ATOM   16106 O O   . VAL D 1 254 ? 164.711 133.171 113.147 1.00 33.89  ? 254 VAL D O   1 
ATOM   16107 C CB  . VAL D 1 254 ? 166.854 130.752 112.283 1.00 23.87  ? 254 VAL D CB  1 
ATOM   16108 C CG1 . VAL D 1 254 ? 166.497 130.519 113.744 1.00 21.26  ? 254 VAL D CG1 1 
ATOM   16109 C CG2 . VAL D 1 254 ? 166.746 129.408 111.557 1.00 16.74  ? 254 VAL D CG2 1 
ATOM   16110 N N   . MET D 1 255 ? 166.638 134.022 112.433 1.00 22.15  ? 255 MET D N   1 
ATOM   16111 C CA  . MET D 1 255 ? 166.490 135.293 113.139 1.00 14.53  ? 255 MET D CA  1 
ATOM   16112 C C   . MET D 1 255 ? 165.345 136.177 112.619 1.00 23.85  ? 255 MET D C   1 
ATOM   16113 O O   . MET D 1 255 ? 164.703 136.812 113.447 1.00 31.57  ? 255 MET D O   1 
ATOM   16114 C CB  . MET D 1 255 ? 167.808 136.067 113.131 1.00 24.33  ? 255 MET D CB  1 
ATOM   16115 C CG  . MET D 1 255 ? 168.896 135.420 113.986 1.00 22.89  ? 255 MET D CG  1 
ATOM   16116 S SD  . MET D 1 255 ? 168.514 135.348 115.755 1.00 45.65  ? 255 MET D SD  1 
ATOM   16117 C CE  . MET D 1 255 ? 170.188 135.456 116.437 1.00 29.01  ? 255 MET D CE  1 
ATOM   16118 N N   . ILE D 1 256 ? 165.009 136.184 111.321 1.00 27.68  ? 256 ILE D N   1 
ATOM   16119 C CA  . ILE D 1 256 ? 163.827 136.958 110.820 1.00 25.01  ? 256 ILE D CA  1 
ATOM   16120 C C   . ILE D 1 256 ? 162.486 136.224 111.044 1.00 30.62  ? 256 ILE D C   1 
ATOM   16121 O O   . ILE D 1 256 ? 161.452 136.846 110.734 1.00 41.06  ? 256 ILE D O   1 
ATOM   16122 C CB  . ILE D 1 256 ? 164.017 137.312 109.330 1.00 27.54  ? 256 ILE D CB  1 
ATOM   16123 C CG1 . ILE D 1 256 ? 163.977 136.066 108.443 1.00 27.38  ? 256 ILE D CG1 1 
ATOM   16124 C CG2 . ILE D 1 256 ? 165.294 138.114 109.125 1.00 27.03  ? 256 ILE D CG2 1 
ATOM   16125 C CD1 . ILE D 1 256 ? 164.063 136.363 106.965 1.00 27.01  ? 256 ILE D CD1 1 
ATOM   16126 N N   . ALA D 1 257 ? 162.465 134.979 111.545 1.00 28.72  ? 257 ALA D N   1 
ATOM   16127 C CA  . ALA D 1 257 ? 161.217 134.257 111.695 1.00 25.99  ? 257 ALA D CA  1 
ATOM   16128 C C   . ALA D 1 257 ? 160.363 134.755 112.869 1.00 34.53  ? 257 ALA D C   1 
ATOM   16129 O O   . ALA D 1 257 ? 160.824 134.816 114.009 1.00 37.47  ? 257 ALA D O   1 
ATOM   16130 C CB  . ALA D 1 257 ? 161.541 132.765 111.812 1.00 24.71  ? 257 ALA D CB  1 
ATOM   16131 N N   . ASP D 1 258 ? 159.110 135.089 112.603 1.00 43.05  ? 258 ASP D N   1 
ATOM   16132 C CA  . ASP D 1 258 ? 157.997 135.119 113.575 1.00 43.07  ? 258 ASP D CA  1 
ATOM   16133 C C   . ASP D 1 258 ? 157.180 133.808 113.290 1.00 48.74  ? 258 ASP D C   1 
ATOM   16134 O O   . ASP D 1 258 ? 157.466 133.141 112.276 1.00 49.14  ? 258 ASP D O   1 
ATOM   16135 C CB  . ASP D 1 258 ? 157.159 136.392 113.450 1.00 47.09  ? 258 ASP D CB  1 
ATOM   16136 C CG  . ASP D 1 258 ? 156.205 136.370 112.268 1.00 51.53  ? 258 ASP D CG  1 
ATOM   16137 O OD1 . ASP D 1 258 ? 155.885 135.263 111.796 1.00 53.99  ? 258 ASP D OD1 1 
ATOM   16138 O OD2 . ASP D 1 258 ? 155.790 137.462 111.831 1.00 47.82  ? 258 ASP D OD2 1 
ATOM   16139 N N   . ASN D 1 259 ? 156.237 133.482 114.166 1.00 44.34  ? 259 ASN D N   1 
ATOM   16140 C CA  . ASN D 1 259 ? 155.500 132.222 114.064 1.00 45.47  ? 259 ASN D CA  1 
ATOM   16141 C C   . ASN D 1 259 ? 154.151 132.363 113.334 1.00 51.16  ? 259 ASN D C   1 
ATOM   16142 O O   . ASN D 1 259 ? 153.318 131.461 113.395 1.00 53.07  ? 259 ASN D O   1 
ATOM   16143 C CB  . ASN D 1 259 ? 155.466 131.570 115.454 1.00 47.98  ? 259 ASN D CB  1 
ATOM   16144 C CG  . ASN D 1 259 ? 156.873 131.331 115.976 1.00 42.84  ? 259 ASN D CG  1 
ATOM   16145 O OD1 . ASN D 1 259 ? 157.642 130.561 115.430 1.00 42.71  ? 259 ASN D OD1 1 
ATOM   16146 N ND2 . ASN D 1 259 ? 157.274 132.001 117.029 1.00 43.99  ? 259 ASN D ND2 1 
ATOM   16147 N N   . SER D 1 260 ? 153.919 133.477 112.628 1.00 53.19  ? 260 SER D N   1 
ATOM   16148 C CA  . SER D 1 260 ? 152.767 133.647 111.732 1.00 52.24  ? 260 SER D CA  1 
ATOM   16149 C C   . SER D 1 260 ? 152.919 132.780 110.469 1.00 52.92  ? 260 SER D C   1 
ATOM   16150 O O   . SER D 1 260 ? 154.047 132.500 110.047 1.00 51.49  ? 260 SER D O   1 
ATOM   16151 C CB  . SER D 1 260 ? 152.579 135.120 111.364 1.00 55.32  ? 260 SER D CB  1 
ATOM   16152 O OG  . SER D 1 260 ? 153.594 135.560 110.496 1.00 54.95  ? 260 SER D OG  1 
ATOM   16153 N N   . PRO D 1 261 ? 151.820 132.319 109.846 1.00 58.49  ? 261 PRO D N   1 
ATOM   16154 C CA  . PRO D 1 261 ? 151.894 131.313 108.786 1.00 56.57  ? 261 PRO D CA  1 
ATOM   16155 C C   . PRO D 1 261 ? 152.516 131.836 107.488 1.00 54.33  ? 261 PRO D C   1 
ATOM   16156 O O   . PRO D 1 261 ? 153.258 131.106 106.834 1.00 54.56  ? 261 PRO D O   1 
ATOM   16157 C CB  . PRO D 1 261 ? 150.457 130.824 108.589 1.00 54.71  ? 261 PRO D CB  1 
ATOM   16158 C CG  . PRO D 1 261 ? 149.599 131.972 109.108 1.00 54.24  ? 261 PRO D CG  1 
ATOM   16159 C CD  . PRO D 1 261 ? 150.440 132.549 110.237 1.00 52.77  ? 261 PRO D CD  1 
ATOM   16160 N N   . GLU D 1 262 ? 152.283 133.100 107.129 1.00 55.90  ? 262 GLU D N   1 
ATOM   16161 C CA  . GLU D 1 262 ? 152.880 133.716 105.940 1.00 57.87  ? 262 GLU D CA  1 
ATOM   16162 C C   . GLU D 1 262 ? 154.388 133.927 106.113 1.00 58.14  ? 262 GLU D C   1 
ATOM   16163 O O   . GLU D 1 262 ? 155.169 133.469 105.286 1.00 61.30  ? 262 GLU D O   1 
ATOM   16164 C CB  . GLU D 1 262 ? 152.144 135.014 105.573 1.00 58.17  ? 262 GLU D CB  1 
ATOM   16165 C CG  . GLU D 1 262 ? 152.730 135.668 104.311 1.00 61.81  ? 262 GLU D CG  1 
ATOM   16166 C CD  . GLU D 1 262 ? 151.815 136.717 103.664 1.00 64.93  ? 262 GLU D CD  1 
ATOM   16167 O OE1 . GLU D 1 262 ? 150.934 137.283 104.347 1.00 61.46  ? 262 GLU D OE1 1 
ATOM   16168 O OE2 . GLU D 1 262 ? 151.984 136.989 102.452 1.00 63.73  ? 262 GLU D OE2 1 
ATOM   16169 N N   . ASN D 1 263 ? 154.828 134.534 107.215 1.00 49.25  ? 263 ASN D N   1 
ATOM   16170 C CA  . ASN D 1 263 ? 156.258 134.685 107.483 1.00 46.54  ? 263 ASN D CA  1 
ATOM   16171 C C   . ASN D 1 263 ? 156.975 133.327 107.548 1.00 47.73  ? 263 ASN D C   1 
ATOM   16172 O O   . ASN D 1 263 ? 158.066 133.180 107.002 1.00 47.51  ? 263 ASN D O   1 
ATOM   16173 C CB  . ASN D 1 263 ? 156.447 135.459 108.787 1.00 45.76  ? 263 ASN D CB  1 
ATOM   16174 C CG  . ASN D 1 263 ? 157.914 135.611 109.111 1.00 46.36  ? 263 ASN D CG  1 
ATOM   16175 O OD1 . ASN D 1 263 ? 158.498 134.822 109.829 1.00 48.67  ? 263 ASN D OD1 1 
ATOM   16176 N ND2 . ASN D 1 263 ? 158.580 136.592 108.571 1.00 47.46  ? 263 ASN D ND2 1 
ATOM   16177 N N   . SER D 1 264 ? 156.341 132.316 108.142 1.00 47.72  ? 264 SER D N   1 
ATOM   16178 C CA  . SER D 1 264 ? 156.892 130.966 108.199 1.00 42.28  ? 264 SER D CA  1 
ATOM   16179 C C   . SER D 1 264 ? 157.050 130.367 106.807 1.00 41.62  ? 264 SER D C   1 
ATOM   16180 O O   . SER D 1 264 ? 158.138 129.912 106.475 1.00 42.97  ? 264 SER D O   1 
ATOM   16181 C CB  . SER D 1 264 ? 156.028 130.055 109.064 1.00 46.36  ? 264 SER D CB  1 
ATOM   16182 O OG  . SER D 1 264 ? 155.929 130.581 110.364 1.00 46.80  ? 264 SER D OG  1 
ATOM   16183 N N   . ALA D 1 265 ? 156.021 130.408 105.958 1.00 49.65  ? 265 ALA D N   1 
ATOM   16184 C CA  . ALA D 1 265 ? 156.099 129.890 104.593 1.00 49.28  ? 265 ALA D CA  1 
ATOM   16185 C C   . ALA D 1 265 ? 157.222 130.549 103.780 1.00 45.20  ? 265 ALA D C   1 
ATOM   16186 O O   . ALA D 1 265 ? 157.944 129.870 103.056 1.00 49.34  ? 265 ALA D O   1 
ATOM   16187 C CB  . ALA D 1 265 ? 154.740 130.093 103.920 1.00 46.66  ? 265 ALA D CB  1 
ATOM   16188 N N   . LEU D 1 266 ? 157.416 131.859 103.940 1.00 39.15  ? 266 LEU D N   1 
ATOM   16189 C CA  . LEU D 1 266 ? 158.458 132.613 103.249 1.00 43.73  ? 266 LEU D CA  1 
ATOM   16190 C C   . LEU D 1 266 ? 159.869 132.318 103.771 1.00 42.38  ? 266 LEU D C   1 
ATOM   16191 O O   . LEU D 1 266 ? 160.773 132.095 102.967 1.00 44.06  ? 266 LEU D O   1 
ATOM   16192 C CB  . LEU D 1 266 ? 158.104 134.108 103.304 1.00 48.84  ? 266 LEU D CB  1 
ATOM   16193 C CG  . LEU D 1 266 ? 156.778 134.441 102.591 1.00 49.43  ? 266 LEU D CG  1 
ATOM   16194 C CD1 . LEU D 1 266 ? 156.440 135.912 102.796 1.00 48.26  ? 266 LEU D CD1 1 
ATOM   16195 C CD2 . LEU D 1 266 ? 156.820 134.106 101.104 1.00 44.61  ? 266 LEU D CD2 1 
ATOM   16196 N N   . VAL D 1 267 ? 160.072 132.231 105.086 1.00 42.74  ? 267 VAL D N   1 
ATOM   16197 C CA  . VAL D 1 267 ? 161.354 131.789 105.664 1.00 38.93  ? 267 VAL D CA  1 
ATOM   16198 C C   . VAL D 1 267 ? 161.686 130.351 105.254 1.00 38.13  ? 267 VAL D C   1 
ATOM   16199 O O   . VAL D 1 267 ? 162.803 130.081 104.834 1.00 41.74  ? 267 VAL D O   1 
ATOM   16200 C CB  . VAL D 1 267 ? 161.363 131.958 107.195 1.00 38.99  ? 267 VAL D CB  1 
ATOM   16201 C CG1 . VAL D 1 267 ? 162.545 131.259 107.863 1.00 41.37  ? 267 VAL D CG1 1 
ATOM   16202 C CG2 . VAL D 1 267 ? 161.454 133.437 107.554 1.00 32.21  ? 267 VAL D CG2 1 
ATOM   16203 N N   . ILE D 1 268 ? 160.718 129.438 105.312 1.00 30.75  ? 268 ILE D N   1 
ATOM   16204 C CA  . ILE D 1 268 ? 160.873 128.031 104.935 1.00 35.51  ? 268 ILE D CA  1 
ATOM   16205 C C   . ILE D 1 268 ? 161.236 127.869 103.449 1.00 39.25  ? 268 ILE D C   1 
ATOM   16206 O O   . ILE D 1 268 ? 162.185 127.156 103.132 1.00 41.13  ? 268 ILE D O   1 
ATOM   16207 C CB  . ILE D 1 268 ? 159.602 127.253 105.345 1.00 35.82  ? 268 ILE D CB  1 
ATOM   16208 C CG1 . ILE D 1 268 ? 159.592 127.082 106.882 1.00 27.95  ? 268 ILE D CG1 1 
ATOM   16209 C CG2 . ILE D 1 268 ? 159.489 125.901 104.634 1.00 30.70  ? 268 ILE D CG2 1 
ATOM   16210 C CD1 . ILE D 1 268 ? 158.251 126.642 107.464 1.00 31.66  ? 268 ILE D CD1 1 
ATOM   16211 N N   . HIS D 1 269 ? 160.552 128.556 102.526 1.00 39.45  ? 269 HIS D N   1 
ATOM   16212 C CA  . HIS D 1 269 ? 160.893 128.490 101.100 1.00 41.19  ? 269 HIS D CA  1 
ATOM   16213 C C   . HIS D 1 269 ? 162.303 129.000 100.815 1.00 40.24  ? 269 HIS D C   1 
ATOM   16214 O O   . HIS D 1 269 ? 163.045 128.391 100.050 1.00 42.38  ? 269 HIS D O   1 
ATOM   16215 C CB  . HIS D 1 269 ? 159.878 129.270 100.248 1.00 45.24  ? 269 HIS D CB  1 
ATOM   16216 C CG  . HIS D 1 269 ? 158.582 128.540 100.007 1.00 49.32  ? 269 HIS D CG  1 
ATOM   16217 N ND1 . HIS D 1 269 ? 158.471 127.263 99.457  1.00 50.39  ? 269 HIS D ND1 1 
ATOM   16218 C CD2 . HIS D 1 269 ? 157.326 129.054 100.163 1.00 49.68  ? 269 HIS D CD2 1 
ATOM   16219 C CE1 . HIS D 1 269 ? 157.156 127.021 99.335  1.00 48.70  ? 269 HIS D CE1 1 
ATOM   16220 N NE2 . HIS D 1 269 ? 156.446 128.079 99.752  1.00 51.32  ? 269 HIS D NE2 1 
ATOM   16221 N N   . MET D 1 270 ? 162.697 130.105 101.442 1.00 37.54  ? 270 MET D N   1 
ATOM   16222 C CA  . MET D 1 270 ? 164.024 130.682 101.269 1.00 35.45  ? 270 MET D CA  1 
ATOM   16223 C C   . MET D 1 270 ? 165.120 129.787 101.857 1.00 34.54  ? 270 MET D C   1 
ATOM   16224 O O   . MET D 1 270 ? 166.138 129.550 101.211 1.00 35.64  ? 270 MET D O   1 
ATOM   16225 C CB  . MET D 1 270 ? 164.018 132.072 101.904 1.00 30.50  ? 270 MET D CB  1 
ATOM   16226 C CG  . MET D 1 270 ? 165.166 132.964 101.428 1.00 33.33  ? 270 MET D CG  1 
ATOM   16227 S SD  . MET D 1 270 ? 165.184 133.459 99.678  1.00 50.01  ? 270 MET D SD  1 
ATOM   16228 C CE  . MET D 1 270 ? 163.438 133.792 99.352  1.00 33.81  ? 270 MET D CE  1 
ATOM   16229 N N   . TYR D 1 271 ? 164.888 129.223 103.043 1.00 32.75  ? 271 TYR D N   1 
ATOM   16230 C CA  . TYR D 1 271 ? 165.793 128.298 103.719 1.00 24.68  ? 271 TYR D CA  1 
ATOM   16231 C C   . TYR D 1 271 ? 166.031 127.016 102.900 1.00 33.32  ? 271 TYR D C   1 
ATOM   16232 O O   . TYR D 1 271 ? 167.177 126.637 102.677 1.00 32.03  ? 271 TYR D O   1 
ATOM   16233 C CB  . TYR D 1 271 ? 165.215 128.011 105.115 1.00 29.68  ? 271 TYR D CB  1 
ATOM   16234 C CG  . TYR D 1 271 ? 166.154 127.293 106.057 1.00 28.78  ? 271 TYR D CG  1 
ATOM   16235 C CD1 . TYR D 1 271 ? 166.411 125.923 105.882 1.00 29.57  ? 271 TYR D CD1 1 
ATOM   16236 C CD2 . TYR D 1 271 ? 166.778 127.997 107.105 1.00 27.27  ? 271 TYR D CD2 1 
ATOM   16237 C CE1 . TYR D 1 271 ? 167.325 125.268 106.717 1.00 27.51  ? 271 TYR D CE1 1 
ATOM   16238 C CE2 . TYR D 1 271 ? 167.682 127.335 107.953 1.00 34.58  ? 271 TYR D CE2 1 
ATOM   16239 C CZ  . TYR D 1 271 ? 167.971 125.974 107.747 1.00 30.57  ? 271 TYR D CZ  1 
ATOM   16240 O OH  . TYR D 1 271 ? 168.848 125.327 108.544 1.00 31.93  ? 271 TYR D OH  1 
ATOM   16241 N N   . ASP D 1 272 ? 164.972 126.379 102.399 1.00 34.76  ? 272 ASP D N   1 
ATOM   16242 C CA  . ASP D 1 272 ? 165.087 125.201 101.536 1.00 31.24  ? 272 ASP D CA  1 
ATOM   16243 C C   . ASP D 1 272 ? 165.768 125.512 100.205 1.00 37.95  ? 272 ASP D C   1 
ATOM   16244 O O   . ASP D 1 272 ? 166.617 124.744 99.758  1.00 41.13  ? 272 ASP D O   1 
ATOM   16245 C CB  . ASP D 1 272 ? 163.704 124.606 101.255 1.00 39.06  ? 272 ASP D CB  1 
ATOM   16246 C CG  . ASP D 1 272 ? 163.079 123.853 102.430 1.00 44.94  ? 272 ASP D CG  1 
ATOM   16247 O OD1 . ASP D 1 272 ? 163.750 123.624 103.459 1.00 38.57  ? 272 ASP D OD1 1 
ATOM   16248 O OD2 . ASP D 1 272 ? 161.915 123.420 102.276 1.00 48.63  ? 272 ASP D OD2 1 
ATOM   16249 N N   . GLY D 1 273 ? 165.446 126.650 99.584  1.00 42.45  ? 273 GLY D N   1 
ATOM   16250 C CA  . GLY D 1 273 ? 166.092 127.112 98.367  1.00 31.66  ? 273 GLY D CA  1 
ATOM   16251 C C   . GLY D 1 273 ? 167.595 127.274 98.547  1.00 34.31  ? 273 GLY D C   1 
ATOM   16252 O O   . GLY D 1 273 ? 168.367 126.814 97.711  1.00 40.70  ? 273 GLY D O   1 
ATOM   16253 N N   . LEU D 1 274 ? 168.048 127.881 99.642  1.00 34.18  ? 274 LEU D N   1 
ATOM   16254 C CA  . LEU D 1 274 ? 169.473 128.069 99.901  1.00 35.65  ? 274 LEU D CA  1 
ATOM   16255 C C   . LEU D 1 274 ? 170.208 126.758 100.206 1.00 39.69  ? 274 LEU D C   1 
ATOM   16256 O O   . LEU D 1 274 ? 171.347 126.603 99.778  1.00 40.38  ? 274 LEU D O   1 
ATOM   16257 C CB  . LEU D 1 274 ? 169.649 129.075 101.036 1.00 33.09  ? 274 LEU D CB  1 
ATOM   16258 C CG  . LEU D 1 274 ? 169.233 130.502 100.660 1.00 34.17  ? 274 LEU D CG  1 
ATOM   16259 C CD1 . LEU D 1 274 ? 169.081 131.284 101.944 1.00 36.90  ? 274 LEU D CD1 1 
ATOM   16260 C CD2 . LEU D 1 274 ? 170.257 131.235 99.804  1.00 30.35  ? 274 LEU D CD2 1 
ATOM   16261 N N   . LEU D 1 275 ? 169.584 125.781 100.869 1.00 40.52  ? 275 LEU D N   1 
ATOM   16262 C CA  . LEU D 1 275 ? 170.167 124.441 100.985 1.00 37.48  ? 275 LEU D CA  1 
ATOM   16263 C C   . LEU D 1 275 ? 170.307 123.743 99.633  1.00 37.73  ? 275 LEU D C   1 
ATOM   16264 O O   . LEU D 1 275 ? 171.355 123.172 99.348  1.00 40.51  ? 275 LEU D O   1 
ATOM   16265 C CB  . LEU D 1 275 ? 169.319 123.553 101.898 1.00 39.89  ? 275 LEU D CB  1 
ATOM   16266 C CG  . LEU D 1 275 ? 169.414 123.860 103.390 1.00 36.61  ? 275 LEU D CG  1 
ATOM   16267 C CD1 . LEU D 1 275 ? 168.547 122.839 104.112 1.00 33.31  ? 275 LEU D CD1 1 
ATOM   16268 C CD2 . LEU D 1 275 ? 170.835 123.721 103.923 1.00 33.25  ? 275 LEU D CD2 1 
ATOM   16269 N N   . GLN D 1 276 ? 169.272 123.854 98.799  1.00 41.74  ? 276 GLN D N   1 
ATOM   16270 C CA  . GLN D 1 276 ? 169.328 123.266 97.431  1.00 38.63  ? 276 GLN D CA  1 
ATOM   16271 C C   . GLN D 1 276 ? 170.455 123.952 96.656  1.00 47.72  ? 276 GLN D C   1 
ATOM   16272 O O   . GLN D 1 276 ? 171.243 123.225 96.019  1.00 51.34  ? 276 GLN D O   1 
ATOM   16273 C CB  . GLN D 1 276 ? 167.971 123.401 96.740  1.00 41.81  ? 276 GLN D CB  1 
ATOM   16274 C CG  . GLN D 1 276 ? 166.877 122.593 97.422  1.00 42.18  ? 276 GLN D CG  1 
ATOM   16275 C CD  . GLN D 1 276 ? 165.693 122.343 96.522  1.00 49.93  ? 276 GLN D CD  1 
ATOM   16276 O OE1 . GLN D 1 276 ? 165.587 122.901 95.433  1.00 52.54  ? 276 GLN D OE1 1 
ATOM   16277 N NE2 . GLN D 1 276 ? 164.789 121.489 96.974  1.00 48.66  ? 276 GLN D NE2 1 
ATOM   16278 N N   . MET D 1 277 ? 170.548 125.287 96.704  1.00 49.97  ? 277 MET D N   1 
ATOM   16279 C CA  . MET D 1 277 ? 171.662 126.020 96.099  1.00 48.63  ? 277 MET D CA  1 
ATOM   16280 C C   . MET D 1 277 ? 173.018 125.555 96.631  1.00 46.20  ? 277 MET D C   1 
ATOM   16281 O O   . MET D 1 277 ? 173.923 125.306 95.841  1.00 51.66  ? 277 MET D O   1 
ATOM   16282 C CB  . MET D 1 277 ? 171.502 127.531 96.327  1.00 50.79  ? 277 MET D CB  1 
ATOM   16283 C CG  . MET D 1 277 ? 170.399 128.140 95.469  1.00 48.27  ? 277 MET D CG  1 
ATOM   16284 S SD  . MET D 1 277 ? 170.854 128.339 93.734  1.00 69.24  ? 277 MET D SD  1 
ATOM   16285 C CE  . MET D 1 277 ? 169.214 128.236 92.990  1.00 58.70  ? 277 MET D CE  1 
ATOM   16286 N N   . GLY D 1 278 ? 173.185 125.372 97.940  1.00 46.73  ? 278 GLY D N   1 
ATOM   16287 C CA  . GLY D 1 278 ? 174.423 124.863 98.527  1.00 47.91  ? 278 GLY D CA  1 
ATOM   16288 C C   . GLY D 1 278 ? 174.794 123.467 98.032  1.00 48.92  ? 278 GLY D C   1 
ATOM   16289 O O   . GLY D 1 278 ? 175.956 123.204 97.733  1.00 49.41  ? 278 GLY D O   1 
ATOM   16290 N N   . ALA D 1 279 ? 173.806 122.597 97.826  1.00 49.60  ? 279 ALA D N   1 
ATOM   16291 C CA  . ALA D 1 279 ? 173.985 121.281 97.227  1.00 48.29  ? 279 ALA D CA  1 
ATOM   16292 C C   . ALA D 1 279 ? 174.500 121.312 95.770  1.00 54.46  ? 279 ALA D C   1 
ATOM   16293 O O   . ALA D 1 279 ? 175.018 120.306 95.290  1.00 56.63  ? 279 ALA D O   1 
ATOM   16294 C CB  . ALA D 1 279 ? 172.654 120.537 97.344  1.00 46.44  ? 279 ALA D CB  1 
ATOM   16295 N N   . ARG D 1 280 ? 174.482 122.508 95.143  1.00 57.81  ? 280 ARG D N   1 
ATOM   16296 C CA  . ARG D 1 280 ? 174.969 122.695 93.739  1.00 52.49  ? 280 ARG D CA  1 
ATOM   16297 C C   . ARG D 1 280 ? 176.218 123.572 93.673  1.00 55.16  ? 280 ARG D C   1 
ATOM   16298 O O   . ARG D 1 280 ? 177.017 123.375 92.739  1.00 59.55  ? 280 ARG D O   1 
ATOM   16299 C CB  . ARG D 1 280 ? 173.963 123.478 92.884  1.00 54.75  ? 280 ARG D CB  1 
ATOM   16300 C CG  . ARG D 1 280 ? 172.661 122.709 92.610  1.00 56.41  ? 280 ARG D CG  1 
ATOM   16301 C CD  . ARG D 1 280 ? 171.587 123.605 91.987  1.00 58.94  ? 280 ARG D CD  1 
ATOM   16302 N NE  . ARG D 1 280 ? 172.081 124.279 90.795  1.00 61.25  ? 280 ARG D NE  1 
ATOM   16303 C CZ  . ARG D 1 280 ? 172.710 125.448 90.799  1.00 60.77  ? 280 ARG D CZ  1 
ATOM   16304 N NH1 . ARG D 1 280 ? 173.123 125.980 89.661  1.00 57.67  ? 280 ARG D NH1 1 
ATOM   16305 N NH2 . ARG D 1 280 ? 172.925 126.082 91.938  1.00 57.95  ? 280 ARG D NH2 1 
ATOM   16306 N N   . LEU D 1 281 ? 176.383 124.502 94.611  1.00 54.01  ? 281 LEU D N   1 
ATOM   16307 C CA  . LEU D 1 281 ? 177.454 125.507 94.580  1.00 52.67  ? 281 LEU D CA  1 
ATOM   16308 C C   . LEU D 1 281 ? 178.606 125.247 95.555  1.00 52.16  ? 281 LEU D C   1 
ATOM   16309 O O   . LEU D 1 281 ? 179.725 125.696 95.313  1.00 55.13  ? 281 LEU D O   1 
ATOM   16310 C CB  . LEU D 1 281 ? 176.842 126.883 94.868  1.00 51.21  ? 281 LEU D CB  1 
ATOM   16311 C CG  . LEU D 1 281 ? 175.783 127.337 93.852  1.00 54.03  ? 281 LEU D CG  1 
ATOM   16312 C CD1 . LEU D 1 281 ? 175.152 128.620 94.360  1.00 55.20  ? 281 LEU D CD1 1 
ATOM   16313 C CD2 . LEU D 1 281 ? 176.382 127.599 92.475  1.00 52.03  ? 281 LEU D CD2 1 
ATOM   16314 N N   . CYS D 1 282 ? 178.359 124.523 96.642  1.00 53.10  ? 282 CYS D N   1 
ATOM   16315 C CA  . CYS D 1 282 ? 179.370 124.109 97.613  1.00 51.35  ? 282 CYS D CA  1 
ATOM   16316 C C   . CYS D 1 282 ? 179.036 122.711 98.172  1.00 54.30  ? 282 CYS D C   1 
ATOM   16317 O O   . CYS D 1 282 ? 178.869 122.547 99.381  1.00 57.03  ? 282 CYS D O   1 
ATOM   16318 C CB  . CYS D 1 282 ? 179.551 125.215 98.673  1.00 53.08  ? 282 CYS D CB  1 
ATOM   16319 S SG  . CYS D 1 282 ? 178.001 125.694 99.491  1.00 55.21  ? 282 CYS D SG  1 
ATOM   16320 N N   . PRO D 1 283 ? 178.951 121.664 97.326  1.00 58.04  ? 283 PRO D N   1 
ATOM   16321 C CA  . PRO D 1 283 ? 178.406 120.356 97.704  1.00 57.18  ? 283 PRO D CA  1 
ATOM   16322 C C   . PRO D 1 283 ? 179.218 119.621 98.783  1.00 57.37  ? 283 PRO D C   1 
ATOM   16323 O O   . PRO D 1 283 ? 178.683 118.773 99.493  1.00 57.58  ? 283 PRO D O   1 
ATOM   16324 C CB  . PRO D 1 283 ? 178.353 119.554 96.402  1.00 54.58  ? 283 PRO D CB  1 
ATOM   16325 C CG  . PRO D 1 283 ? 179.423 120.191 95.526  1.00 57.67  ? 283 PRO D CG  1 
ATOM   16326 C CD  . PRO D 1 283 ? 179.353 121.658 95.926  1.00 57.53  ? 283 PRO D CD  1 
ATOM   16327 N N   . THR D 1 284 ? 180.497 119.960 98.942  1.00 58.52  ? 284 THR D N   1 
ATOM   16328 C CA  . THR D 1 284 ? 181.359 119.461 100.023 1.00 59.03  ? 284 THR D CA  1 
ATOM   16329 C C   . THR D 1 284 ? 181.004 120.031 101.411 1.00 58.07  ? 284 THR D C   1 
ATOM   16330 O O   . THR D 1 284 ? 181.405 119.471 102.432 1.00 58.47  ? 284 THR D O   1 
ATOM   16331 C CB  . THR D 1 284 ? 182.834 119.709 99.655  1.00 61.76  ? 284 THR D CB  1 
ATOM   16332 O OG1 . THR D 1 284 ? 183.692 118.961 100.478 1.00 63.95  ? 284 THR D OG1 1 
ATOM   16333 C CG2 . THR D 1 284 ? 183.281 121.167 99.766  1.00 58.13  ? 284 THR D CG2 1 
ATOM   16334 N N   . VAL D 1 285 ? 180.235 121.123 101.486 1.00 54.61  ? 285 VAL D N   1 
ATOM   16335 C CA  . VAL D 1 285 ? 179.979 121.868 102.730 1.00 52.48  ? 285 VAL D CA  1 
ATOM   16336 C C   . VAL D 1 285 ? 178.599 121.562 103.306 1.00 52.63  ? 285 VAL D C   1 
ATOM   16337 O O   . VAL D 1 285 ? 177.572 121.736 102.652 1.00 53.61  ? 285 VAL D O   1 
ATOM   16338 C CB  . VAL D 1 285 ? 180.144 123.385 102.531 1.00 53.07  ? 285 VAL D CB  1 
ATOM   16339 C CG1 . VAL D 1 285 ? 179.947 124.138 103.847 1.00 52.30  ? 285 VAL D CG1 1 
ATOM   16340 C CG2 . VAL D 1 285 ? 181.536 123.725 102.004 1.00 52.40  ? 285 VAL D CG2 1 
ATOM   16341 N N   . GLN D 1 286 ? 178.577 121.158 104.575 1.00 51.26  ? 286 GLN D N   1 
ATOM   16342 C CA  . GLN D 1 286 ? 177.373 121.022 105.389 1.00 49.21  ? 286 GLN D CA  1 
ATOM   16343 C C   . GLN D 1 286 ? 176.980 122.386 105.988 1.00 47.29  ? 286 GLN D C   1 
ATOM   16344 O O   . GLN D 1 286 ? 177.431 122.753 107.071 1.00 47.30  ? 286 GLN D O   1 
ATOM   16345 C CB  . GLN D 1 286 ? 177.642 119.980 106.488 1.00 50.01  ? 286 GLN D CB  1 
ATOM   16346 C CG  . GLN D 1 286 ? 177.873 118.551 105.974 1.00 49.38  ? 286 GLN D CG  1 
ATOM   16347 C CD  . GLN D 1 286 ? 176.562 117.816 105.723 1.00 56.44  ? 286 GLN D CD  1 
ATOM   16348 O OE1 . GLN D 1 286 ? 176.051 117.755 104.615 1.00 55.17  ? 286 GLN D OE1 1 
ATOM   16349 N NE2 . GLN D 1 286 ? 175.966 117.241 106.742 1.00 54.56  ? 286 GLN D NE2 1 
ATOM   16350 N N   . LEU D 1 287 ? 176.138 123.161 105.297 1.00 41.88  ? 287 LEU D N   1 
ATOM   16351 C CA  . LEU D 1 287 ? 175.784 124.530 105.713 1.00 36.66  ? 287 LEU D CA  1 
ATOM   16352 C C   . LEU D 1 287 ? 175.071 124.603 107.072 1.00 42.31  ? 287 LEU D C   1 
ATOM   16353 O O   . LEU D 1 287 ? 175.236 125.569 107.809 1.00 43.55  ? 287 LEU D O   1 
ATOM   16354 C CB  . LEU D 1 287 ? 174.896 125.187 104.646 1.00 38.54  ? 287 LEU D CB  1 
ATOM   16355 C CG  . LEU D 1 287 ? 175.549 125.419 103.278 1.00 40.81  ? 287 LEU D CG  1 
ATOM   16356 C CD1 . LEU D 1 287 ? 174.501 125.988 102.330 1.00 38.96  ? 287 LEU D CD1 1 
ATOM   16357 C CD2 . LEU D 1 287 ? 176.709 126.404 103.347 1.00 41.07  ? 287 LEU D CD2 1 
ATOM   16358 N N   . GLU D 1 288 ? 174.309 123.576 107.434 1.00 39.27  ? 288 GLU D N   1 
ATOM   16359 C CA  . GLU D 1 288 ? 173.637 123.483 108.733 1.00 29.86  ? 288 GLU D CA  1 
ATOM   16360 C C   . GLU D 1 288 ? 174.544 123.019 109.878 1.00 35.20  ? 288 GLU D C   1 
ATOM   16361 O O   . GLU D 1 288 ? 174.103 122.989 111.019 1.00 44.90  ? 288 GLU D O   1 
ATOM   16362 C CB  . GLU D 1 288 ? 172.446 122.534 108.648 1.00 35.90  ? 288 GLU D CB  1 
ATOM   16363 C CG  . GLU D 1 288 ? 171.420 122.974 107.618 1.00 31.43  ? 288 GLU D CG  1 
ATOM   16364 C CD  . GLU D 1 288 ? 170.133 122.182 107.799 1.00 40.78  ? 288 GLU D CD  1 
ATOM   16365 O OE1 . GLU D 1 288 ? 170.180 120.935 107.763 1.00 47.11  ? 288 GLU D OE1 1 
ATOM   16366 O OE2 . GLU D 1 288 ? 169.061 122.793 107.975 1.00 38.59  ? 288 GLU D OE2 1 
ATOM   16367 N N   . GLU D 1 289 ? 175.793 122.635 109.619 1.00 38.07  ? 289 GLU D N   1 
ATOM   16368 C CA  . GLU D 1 289 ? 176.764 122.304 110.672 1.00 40.72  ? 289 GLU D CA  1 
ATOM   16369 C C   . GLU D 1 289 ? 177.630 123.505 111.074 1.00 43.23  ? 289 GLU D C   1 
ATOM   16370 O O   . GLU D 1 289 ? 178.369 123.432 112.054 1.00 48.39  ? 289 GLU D O   1 
ATOM   16371 C CB  . GLU D 1 289 ? 177.638 121.114 110.255 1.00 44.13  ? 289 GLU D CB  1 
ATOM   16372 C CG  . GLU D 1 289 ? 176.834 119.810 110.192 1.00 43.46  ? 289 GLU D CG  1 
ATOM   16373 C CD  . GLU D 1 289 ? 177.701 118.582 109.860 1.00 51.38  ? 289 GLU D CD  1 
ATOM   16374 O OE1 . GLU D 1 289 ? 178.893 118.545 110.236 1.00 50.78  ? 289 GLU D OE1 1 
ATOM   16375 O OE2 . GLU D 1 289 ? 177.176 117.640 109.233 1.00 54.53  ? 289 GLU D OE2 1 
ATOM   16376 N N   . ILE D 1 290 ? 177.541 124.621 110.345 1.00 42.16  ? 290 ILE D N   1 
ATOM   16377 C CA  . ILE D 1 290 ? 178.237 125.863 110.679 1.00 35.38  ? 290 ILE D CA  1 
ATOM   16378 C C   . ILE D 1 290 ? 177.642 126.430 111.972 1.00 33.93  ? 290 ILE D C   1 
ATOM   16379 O O   . ILE D 1 290 ? 176.437 126.647 112.071 1.00 39.00  ? 290 ILE D O   1 
ATOM   16380 C CB  . ILE D 1 290 ? 178.173 126.874 109.509 1.00 37.21  ? 290 ILE D CB  1 
ATOM   16381 C CG1 . ILE D 1 290 ? 178.829 126.292 108.239 1.00 33.88  ? 290 ILE D CG1 1 
ATOM   16382 C CG2 . ILE D 1 290 ? 178.863 128.190 109.908 1.00 36.23  ? 290 ILE D CG2 1 
ATOM   16383 C CD1 . ILE D 1 290 ? 178.589 127.103 106.970 1.00 36.59  ? 290 ILE D CD1 1 
ATOM   16384 N N   . SER D 1 291 ? 178.491 126.700 112.963 1.00 33.53  ? 291 SER D N   1 
ATOM   16385 C CA  . SER D 1 291 ? 178.096 127.298 114.238 1.00 27.98  ? 291 SER D CA  1 
ATOM   16386 C C   . SER D 1 291 ? 178.411 128.789 114.277 1.00 36.38  ? 291 SER D C   1 
ATOM   16387 O O   . SER D 1 291 ? 179.496 129.209 113.877 1.00 44.46  ? 291 SER D O   1 
ATOM   16388 C CB  . SER D 1 291 ? 178.776 126.593 115.408 1.00 28.48  ? 291 SER D CB  1 
ATOM   16389 O OG  . SER D 1 291 ? 178.259 125.292 115.547 1.00 37.22  ? 291 SER D OG  1 
ATOM   16390 N N   . ASN D 1 292 ? 177.483 129.598 114.770 1.00 31.91  ? 292 ASN D N   1 
ATOM   16391 C CA  . ASN D 1 292 ? 177.734 131.010 115.052 1.00 32.35  ? 292 ASN D CA  1 
ATOM   16392 C C   . ASN D 1 292 ? 178.639 131.196 116.294 1.00 29.53  ? 292 ASN D C   1 
ATOM   16393 O O   . ASN D 1 292 ? 179.084 130.223 116.904 1.00 39.16  ? 292 ASN D O   1 
ATOM   16394 C CB  . ASN D 1 292 ? 176.386 131.754 115.096 1.00 26.06  ? 292 ASN D CB  1 
ATOM   16395 C CG  . ASN D 1 292 ? 175.536 131.516 116.319 1.00 25.93  ? 292 ASN D CG  1 
ATOM   16396 O OD1 . ASN D 1 292 ? 175.937 130.892 117.285 1.00 33.55  ? 292 ASN D OD1 1 
ATOM   16397 N ND2 . ASN D 1 292 ? 174.345 132.036 116.329 1.00 28.64  ? 292 ASN D ND2 1 
ATOM   16398 N N   . HIS D 1 293 ? 178.933 132.431 116.703 1.00 34.59  ? 293 HIS D N   1 
ATOM   16399 C CA  . HIS D 1 293 ? 179.814 132.697 117.857 1.00 35.06  ? 293 HIS D CA  1 
ATOM   16400 C C   . HIS D 1 293 ? 179.262 132.206 119.201 1.00 33.97  ? 293 HIS D C   1 
ATOM   16401 O O   . HIS D 1 293 ? 180.035 131.977 120.126 1.00 40.06  ? 293 HIS D O   1 
ATOM   16402 C CB  . HIS D 1 293 ? 180.137 134.196 117.929 1.00 33.07  ? 293 HIS D CB  1 
ATOM   16403 C CG  . HIS D 1 293 ? 180.903 134.746 116.752 1.00 34.90  ? 293 HIS D CG  1 
ATOM   16404 N ND1 . HIS D 1 293 ? 181.103 136.101 116.503 1.00 42.46  ? 293 HIS D ND1 1 
ATOM   16405 C CD2 . HIS D 1 293 ? 181.560 134.028 115.796 1.00 34.43  ? 293 HIS D CD2 1 
ATOM   16406 C CE1 . HIS D 1 293 ? 181.849 136.173 115.391 1.00 40.23  ? 293 HIS D CE1 1 
ATOM   16407 N NE2 . HIS D 1 293 ? 182.135 134.941 114.947 1.00 36.34  ? 293 HIS D NE2 1 
ATOM   16408 N N   . GLN D 1 294 ? 177.946 132.002 119.322 1.00 37.59  ? 294 GLN D N   1 
ATOM   16409 C CA  . GLN D 1 294 ? 177.311 131.362 120.480 1.00 37.26  ? 294 GLN D CA  1 
ATOM   16410 C C   . GLN D 1 294 ? 177.376 129.819 120.441 1.00 41.81  ? 294 GLN D C   1 
ATOM   16411 O O   . GLN D 1 294 ? 176.841 129.158 121.329 1.00 43.28  ? 294 GLN D O   1 
ATOM   16412 C CB  . GLN D 1 294 ? 175.861 131.849 120.637 1.00 36.68  ? 294 GLN D CB  1 
ATOM   16413 C CG  . GLN D 1 294 ? 175.759 133.363 120.841 1.00 41.30  ? 294 GLN D CG  1 
ATOM   16414 C CD  . GLN D 1 294 ? 174.351 133.849 121.181 1.00 48.68  ? 294 GLN D CD  1 
ATOM   16415 O OE1 . GLN D 1 294 ? 173.444 133.094 121.505 1.00 49.02  ? 294 GLN D OE1 1 
ATOM   16416 N NE2 . GLN D 1 294 ? 174.113 135.138 121.139 1.00 44.33  ? 294 GLN D NE2 1 
ATOM   16417 N N   . GLY D 1 295 ? 178.003 129.227 119.418 1.00 38.61  ? 295 GLY D N   1 
ATOM   16418 C CA  . GLY D 1 295 ? 178.104 127.781 119.235 1.00 33.27  ? 295 GLY D CA  1 
ATOM   16419 C C   . GLY D 1 295 ? 176.824 127.127 118.710 1.00 38.98  ? 295 GLY D C   1 
ATOM   16420 O O   . GLY D 1 295 ? 176.625 125.933 118.911 1.00 44.31  ? 295 GLY D O   1 
ATOM   16421 N N   . LEU D 1 296 ? 175.937 127.890 118.071 1.00 33.55  ? 296 LEU D N   1 
ATOM   16422 C CA  . LEU D 1 296 ? 174.641 127.408 117.598 1.00 24.93  ? 296 LEU D CA  1 
ATOM   16423 C C   . LEU D 1 296 ? 174.658 127.198 116.084 1.00 22.90  ? 296 LEU D C   1 
ATOM   16424 O O   . LEU D 1 296 ? 175.041 128.080 115.323 1.00 31.16  ? 296 LEU D O   1 
ATOM   16425 C CB  . LEU D 1 296 ? 173.529 128.392 117.994 1.00 24.38  ? 296 LEU D CB  1 
ATOM   16426 C CG  . LEU D 1 296 ? 173.422 128.681 119.498 1.00 25.97  ? 296 LEU D CG  1 
ATOM   16427 C CD1 . LEU D 1 296 ? 172.527 129.888 119.714 1.00 30.68  ? 296 LEU D CD1 1 
ATOM   16428 C CD2 . LEU D 1 296 ? 172.832 127.517 120.276 1.00 23.43  ? 296 LEU D CD2 1 
ATOM   16429 N N   . THR D 1 297 ? 174.197 126.039 115.633 1.00 29.86  ? 297 THR D N   1 
ATOM   16430 C CA  . THR D 1 297 ? 173.778 125.797 114.250 1.00 24.33  ? 297 THR D CA  1 
ATOM   16431 C C   . THR D 1 297 ? 172.390 126.404 113.997 1.00 20.55  ? 297 THR D C   1 
ATOM   16432 O O   . THR D 1 297 ? 171.711 126.755 114.961 1.00 31.00  ? 297 THR D O   1 
ATOM   16433 C CB  . THR D 1 297 ? 173.749 124.291 113.976 1.00 27.18  ? 297 THR D CB  1 
ATOM   16434 O OG1 . THR D 1 297 ? 172.820 123.641 114.808 1.00 33.94  ? 297 THR D OG1 1 
ATOM   16435 C CG2 . THR D 1 297 ? 175.102 123.629 114.186 1.00 20.54  ? 297 THR D CG2 1 
ATOM   16436 N N   . PRO D 1 298 ? 171.902 126.534 112.751 1.00 18.71  ? 298 PRO D N   1 
ATOM   16437 C CA  . PRO D 1 298 ? 170.560 127.063 112.501 1.00 17.52  ? 298 PRO D CA  1 
ATOM   16438 C C   . PRO D 1 298 ? 169.426 126.335 113.251 1.00 17.44  ? 298 PRO D C   1 
ATOM   16439 O O   . PRO D 1 298 ? 168.534 126.994 113.769 1.00 22.84  ? 298 PRO D O   1 
ATOM   16440 C CB  . PRO D 1 298 ? 170.389 126.990 110.989 1.00 20.19  ? 298 PRO D CB  1 
ATOM   16441 C CG  . PRO D 1 298 ? 171.810 127.087 110.450 1.00 10.15  ? 298 PRO D CG  1 
ATOM   16442 C CD  . PRO D 1 298 ? 172.621 126.344 111.498 1.00 14.12  ? 298 PRO D CD  1 
ATOM   16443 N N   . LEU D 1 299 ? 169.475 125.003 113.399 1.00 17.48  ? 299 LEU D N   1 
ATOM   16444 C CA  . LEU D 1 299 ? 168.493 124.233 114.181 1.00 13.01  ? 299 LEU D CA  1 
ATOM   16445 C C   . LEU D 1 299 ? 168.564 124.525 115.688 1.00 22.21  ? 299 LEU D C   1 
ATOM   16446 O O   . LEU D 1 299 ? 167.537 124.698 116.336 1.00 22.81  ? 299 LEU D O   1 
ATOM   16447 C CB  . LEU D 1 299 ? 168.706 122.734 113.901 1.00 15.92  ? 299 LEU D CB  1 
ATOM   16448 C CG  . LEU D 1 299 ? 167.779 121.795 114.691 1.00 18.92  ? 299 LEU D CG  1 
ATOM   16449 C CD1 . LEU D 1 299 ? 166.312 121.931 114.307 1.00 16.51  ? 299 LEU D CD1 1 
ATOM   16450 C CD2 . LEU D 1 299 ? 168.202 120.350 114.486 1.00 17.57  ? 299 LEU D CD2 1 
ATOM   16451 N N   . LYS D 1 300 ? 169.772 124.620 116.249 1.00 23.63  ? 300 LYS D N   1 
ATOM   16452 C CA  . LYS D 1 300 ? 169.996 125.002 117.649 1.00 8.45   ? 300 LYS D CA  1 
ATOM   16453 C C   . LYS D 1 300 ? 169.586 126.445 117.930 1.00 18.42  ? 300 LYS D C   1 
ATOM   16454 O O   . LYS D 1 300 ? 169.025 126.723 118.980 1.00 19.93  ? 300 LYS D O   1 
ATOM   16455 C CB  . LYS D 1 300 ? 171.464 124.770 118.013 1.00 21.30  ? 300 LYS D CB  1 
ATOM   16456 C CG  . LYS D 1 300 ? 171.820 123.286 118.128 1.00 19.51  ? 300 LYS D CG  1 
ATOM   16457 C CD  . LYS D 1 300 ? 173.256 123.121 118.632 1.00 19.44  ? 300 LYS D CD  1 
ATOM   16458 C CE  . LYS D 1 300 ? 173.664 121.651 118.603 1.00 21.92  ? 300 LYS D CE  1 
ATOM   16459 N NZ  . LYS D 1 300 ? 174.984 121.435 119.241 1.00 30.28  ? 300 LYS D NZ  1 
ATOM   16460 N N   . LEU D 1 301 ? 169.814 127.363 116.993 1.00 25.60  ? 301 LEU D N   1 
ATOM   16461 C CA  . LEU D 1 301 ? 169.324 128.735 117.067 1.00 10.90  ? 301 LEU D CA  1 
ATOM   16462 C C   . LEU D 1 301 ? 167.796 128.808 116.960 1.00 17.34  ? 301 LEU D C   1 
ATOM   16463 O O   . LEU D 1 301 ? 167.178 129.558 117.704 1.00 26.60  ? 301 LEU D O   1 
ATOM   16464 C CB  . LEU D 1 301 ? 170.037 129.561 115.989 1.00 28.60  ? 301 LEU D CB  1 
ATOM   16465 C CG  . LEU D 1 301 ? 169.703 131.060 116.038 1.00 25.01  ? 301 LEU D CG  1 
ATOM   16466 C CD1 . LEU D 1 301 ? 170.275 131.721 117.282 1.00 22.47  ? 301 LEU D CD1 1 
ATOM   16467 C CD2 . LEU D 1 301 ? 170.292 131.752 114.821 1.00 18.00  ? 301 LEU D CD2 1 
ATOM   16468 N N   . ALA D 1 302 ? 167.160 128.001 116.111 1.00 21.02  ? 302 ALA D N   1 
ATOM   16469 C CA  . ALA D 1 302 ? 165.703 127.940 116.036 1.00 21.88  ? 302 ALA D CA  1 
ATOM   16470 C C   . ALA D 1 302 ? 165.086 127.427 117.346 1.00 18.90  ? 302 ALA D C   1 
ATOM   16471 O O   . ALA D 1 302 ? 164.112 127.993 117.828 1.00 21.27  ? 302 ALA D O   1 
ATOM   16472 C CB  . ALA D 1 302 ? 165.291 127.099 114.824 1.00 12.83  ? 302 ALA D CB  1 
ATOM   16473 N N   . ALA D 1 303 ? 165.703 126.423 117.977 1.00 22.88  ? 303 ALA D N   1 
ATOM   16474 C CA  . ALA D 1 303 ? 165.354 125.961 119.315 1.00 15.38  ? 303 ALA D CA  1 
ATOM   16475 C C   . ALA D 1 303 ? 165.582 127.036 120.396 1.00 24.60  ? 303 ALA D C   1 
ATOM   16476 O O   . ALA D 1 303 ? 164.704 127.268 121.218 1.00 29.84  ? 303 ALA D O   1 
ATOM   16477 C CB  . ALA D 1 303 ? 166.165 124.700 119.611 1.00 24.93  ? 303 ALA D CB  1 
ATOM   16478 N N   . LYS D 1 304 ? 166.726 127.732 120.408 1.00 29.96  ? 304 LYS D N   1 
ATOM   16479 C CA  . LYS D 1 304 ? 167.029 128.751 121.420 1.00 20.38  ? 304 LYS D CA  1 
ATOM   16480 C C   . LYS D 1 304 ? 166.093 129.946 121.342 1.00 18.54  ? 304 LYS D C   1 
ATOM   16481 O O   . LYS D 1 304 ? 165.570 130.396 122.355 1.00 32.35  ? 304 LYS D O   1 
ATOM   16482 C CB  . LYS D 1 304 ? 168.492 129.198 121.311 1.00 21.09  ? 304 LYS D CB  1 
ATOM   16483 C CG  . LYS D 1 304 ? 168.857 130.080 122.509 1.00 30.04  ? 304 LYS D CG  1 
ATOM   16484 C CD  . LYS D 1 304 ? 170.316 130.511 122.470 1.00 34.83  ? 304 LYS D CD  1 
ATOM   16485 C CE  . LYS D 1 304 ? 170.615 131.447 123.640 1.00 34.85  ? 304 LYS D CE  1 
ATOM   16486 N NZ  . LYS D 1 304 ? 172.032 131.880 123.646 1.00 36.77  ? 304 LYS D NZ  1 
ATOM   16487 N N   . GLU D 1 305 ? 165.861 130.461 120.145 1.00 28.13  ? 305 GLU D N   1 
ATOM   16488 C CA  . GLU D 1 305 ? 165.043 131.649 119.915 1.00 21.07  ? 305 GLU D CA  1 
ATOM   16489 C C   . GLU D 1 305 ? 163.536 131.346 119.843 1.00 25.61  ? 305 GLU D C   1 
ATOM   16490 O O   . GLU D 1 305 ? 162.740 132.249 119.604 1.00 33.40  ? 305 GLU D O   1 
ATOM   16491 C CB  . GLU D 1 305 ? 165.564 132.385 118.674 1.00 21.28  ? 305 GLU D CB  1 
ATOM   16492 C CG  . GLU D 1 305 ? 167.040 132.810 118.734 1.00 25.37  ? 305 GLU D CG  1 
ATOM   16493 C CD  . GLU D 1 305 ? 167.394 133.714 119.924 1.00 32.00  ? 305 GLU D CD  1 
ATOM   16494 O OE1 . GLU D 1 305 ? 166.504 134.429 120.440 1.00 36.97  ? 305 GLU D OE1 1 
ATOM   16495 O OE2 . GLU D 1 305 ? 168.571 133.734 120.336 1.00 36.71  ? 305 GLU D OE2 1 
ATOM   16496 N N   . GLY D 1 306 ? 163.121 130.096 120.059 1.00 11.72  ? 306 GLY D N   1 
ATOM   16497 C CA  . GLY D 1 306 ? 161.717 129.686 120.099 1.00 9.37   ? 306 GLY D CA  1 
ATOM   16498 C C   . GLY D 1 306 ? 160.994 129.757 118.757 1.00 19.24  ? 306 GLY D C   1 
ATOM   16499 O O   . GLY D 1 306 ? 159.793 130.012 118.716 1.00 30.45  ? 306 GLY D O   1 
ATOM   16500 N N   . LYS D 1 307 ? 161.713 129.589 117.643 1.00 27.57  ? 307 LYS D N   1 
ATOM   16501 C CA  . LYS D 1 307 ? 161.186 129.751 116.283 1.00 22.61  ? 307 LYS D CA  1 
ATOM   16502 C C   . LYS D 1 307 ? 160.531 128.457 115.827 1.00 20.17  ? 307 LYS D C   1 
ATOM   16503 O O   . LYS D 1 307 ? 161.057 127.746 114.985 1.00 23.49  ? 307 LYS D O   1 
ATOM   16504 C CB  . LYS D 1 307 ? 162.295 130.245 115.338 1.00 18.76  ? 307 LYS D CB  1 
ATOM   16505 C CG  . LYS D 1 307 ? 163.033 131.491 115.824 1.00 13.17  ? 307 LYS D CG  1 
ATOM   16506 C CD  . LYS D 1 307 ? 162.082 132.641 116.167 1.00 17.47  ? 307 LYS D CD  1 
ATOM   16507 C CE  . LYS D 1 307 ? 162.822 133.944 116.466 1.00 24.71  ? 307 LYS D CE  1 
ATOM   16508 N NZ  . LYS D 1 307 ? 163.291 134.626 115.239 1.00 21.56  ? 307 LYS D NZ  1 
ATOM   16509 N N   . ILE D 1 308 ? 159.414 128.106 116.447 1.00 24.81  ? 308 ILE D N   1 
ATOM   16510 C CA  . ILE D 1 308 ? 158.830 126.767 116.381 1.00 27.76  ? 308 ILE D CA  1 
ATOM   16511 C C   . ILE D 1 308 ? 158.455 126.317 114.966 1.00 25.90  ? 308 ILE D C   1 
ATOM   16512 O O   . ILE D 1 308 ? 158.582 125.139 114.649 1.00 30.17  ? 308 ILE D O   1 
ATOM   16513 C CB  . ILE D 1 308 ? 157.662 126.642 117.380 1.00 33.40  ? 308 ILE D CB  1 
ATOM   16514 C CG1 . ILE D 1 308 ? 157.151 125.193 117.374 1.00 35.40  ? 308 ILE D CG1 1 
ATOM   16515 C CG2 . ILE D 1 308 ? 156.523 127.633 117.106 1.00 25.71  ? 308 ILE D CG2 1 
ATOM   16516 C CD1 . ILE D 1 308 ? 156.256 124.862 118.554 1.00 26.87  ? 308 ILE D CD1 1 
ATOM   16517 N N   . GLU D 1 309 ? 158.026 127.224 114.094 1.00 33.00  ? 309 GLU D N   1 
ATOM   16518 C CA  . GLU D 1 309 ? 157.599 126.873 112.740 1.00 31.64  ? 309 GLU D CA  1 
ATOM   16519 C C   . GLU D 1 309 ? 158.779 126.457 111.843 1.00 28.67  ? 309 GLU D C   1 
ATOM   16520 O O   . GLU D 1 309 ? 158.729 125.405 111.210 1.00 33.10  ? 309 GLU D O   1 
ATOM   16521 C CB  . GLU D 1 309 ? 156.804 128.039 112.143 1.00 34.52  ? 309 GLU D CB  1 
ATOM   16522 C CG  . GLU D 1 309 ? 155.569 128.428 112.977 1.00 29.62  ? 309 GLU D CG  1 
ATOM   16523 C CD  . GLU D 1 309 ? 154.570 127.275 113.116 1.00 39.76  ? 309 GLU D CD  1 
ATOM   16524 O OE1 . GLU D 1 309 ? 154.255 126.624 112.097 1.00 38.84  ? 309 GLU D OE1 1 
ATOM   16525 O OE2 . GLU D 1 309 ? 154.113 126.963 114.238 1.00 42.35  ? 309 GLU D OE2 1 
ATOM   16526 N N   . ILE D 1 310 ? 159.875 127.220 111.837 1.00 20.17  ? 310 ILE D N   1 
ATOM   16527 C CA  . ILE D 1 310 ? 161.111 126.841 111.134 1.00 17.68  ? 310 ILE D CA  1 
ATOM   16528 C C   . ILE D 1 310 ? 161.864 125.720 111.862 1.00 21.24  ? 310 ILE D C   1 
ATOM   16529 O O   . ILE D 1 310 ? 162.466 124.875 111.213 1.00 34.42  ? 310 ILE D O   1 
ATOM   16530 C CB  . ILE D 1 310 ? 161.986 128.079 110.820 1.00 23.57  ? 310 ILE D CB  1 
ATOM   16531 C CG1 . ILE D 1 310 ? 163.238 127.781 109.969 1.00 31.86  ? 310 ILE D CG1 1 
ATOM   16532 C CG2 . ILE D 1 310 ? 162.470 128.795 112.083 1.00 20.72  ? 310 ILE D CG2 1 
ATOM   16533 C CD1 . ILE D 1 310 ? 162.947 127.172 108.598 1.00 28.47  ? 310 ILE D CD1 1 
ATOM   16534 N N   . PHE D 1 311 ? 161.779 125.638 113.189 1.00 25.94  ? 311 PHE D N   1 
ATOM   16535 C CA  . PHE D 1 311 ? 162.323 124.534 113.973 1.00 16.36  ? 311 PHE D CA  1 
ATOM   16536 C C   . PHE D 1 311 ? 161.667 123.202 113.599 1.00 19.12  ? 311 PHE D C   1 
ATOM   16537 O O   . PHE D 1 311 ? 162.371 122.277 113.213 1.00 23.88  ? 311 PHE D O   1 
ATOM   16538 C CB  . PHE D 1 311 ? 162.159 124.845 115.466 1.00 17.49  ? 311 PHE D CB  1 
ATOM   16539 C CG  . PHE D 1 311 ? 162.574 123.721 116.381 1.00 14.11  ? 311 PHE D CG  1 
ATOM   16540 C CD1 . PHE D 1 311 ? 163.935 123.431 116.551 1.00 16.57  ? 311 PHE D CD1 1 
ATOM   16541 C CD2 . PHE D 1 311 ? 161.604 122.936 117.029 1.00 13.75  ? 311 PHE D CD2 1 
ATOM   16542 C CE1 . PHE D 1 311 ? 164.326 122.333 117.322 1.00 18.21  ? 311 PHE D CE1 1 
ATOM   16543 C CE2 . PHE D 1 311 ? 161.999 121.853 117.826 1.00 16.90  ? 311 PHE D CE2 1 
ATOM   16544 C CZ  . PHE D 1 311 ? 163.356 121.542 117.954 1.00 22.51  ? 311 PHE D CZ  1 
ATOM   16545 N N   . ARG D 1 312 ? 160.329 123.123 113.614 1.00 19.19  ? 312 ARG D N   1 
ATOM   16546 C CA  . ARG D 1 312 ? 159.569 121.954 113.161 1.00 12.33  ? 312 ARG D CA  1 
ATOM   16547 C C   . ARG D 1 312 ? 159.913 121.594 111.724 1.00 27.71  ? 312 ARG D C   1 
ATOM   16548 O O   . ARG D 1 312 ? 160.136 120.426 111.434 1.00 34.01  ? 312 ARG D O   1 
ATOM   16549 C CB  . ARG D 1 312 ? 158.064 122.234 113.279 1.00 21.53  ? 312 ARG D CB  1 
ATOM   16550 C CG  . ARG D 1 312 ? 157.220 120.975 113.042 1.00 23.09  ? 312 ARG D CG  1 
ATOM   16551 C CD  . ARG D 1 312 ? 155.737 121.259 112.796 1.00 28.73  ? 312 ARG D CD  1 
ATOM   16552 N NE  . ARG D 1 312 ? 155.155 122.184 113.787 1.00 37.09  ? 312 ARG D NE  1 
ATOM   16553 C CZ  . ARG D 1 312 ? 154.817 123.446 113.584 1.00 36.45  ? 312 ARG D CZ  1 
ATOM   16554 N NH1 . ARG D 1 312 ? 154.408 124.185 114.567 1.00 30.38  ? 312 ARG D NH1 1 
ATOM   16555 N NH2 . ARG D 1 312 ? 154.882 123.991 112.411 1.00 29.65  ? 312 ARG D NH2 1 
ATOM   16556 N N   . HIS D 1 313 ? 159.980 122.588 110.838 1.00 25.52  ? 313 HIS D N   1 
ATOM   16557 C CA  . HIS D 1 313 ? 160.323 122.366 109.448 1.00 23.12  ? 313 HIS D CA  1 
ATOM   16558 C C   . HIS D 1 313 ? 161.695 121.718 109.298 1.00 23.51  ? 313 HIS D C   1 
ATOM   16559 O O   . HIS D 1 313 ? 161.749 120.655 108.650 1.00 32.28  ? 313 HIS D O   1 
ATOM   16560 C CB  . HIS D 1 313 ? 160.272 123.702 108.692 1.00 25.43  ? 313 HIS D CB  1 
ATOM   16561 C CG  . HIS D 1 313 ? 161.081 123.708 107.441 1.00 37.42  ? 313 HIS D CG  1 
ATOM   16562 N ND1 . HIS D 1 313 ? 160.623 123.150 106.264 1.00 22.71  ? 313 HIS D ND1 1 
ATOM   16563 C CD2 . HIS D 1 313 ? 162.314 124.193 107.179 1.00 39.50  ? 313 HIS D CD2 1 
ATOM   16564 C CE1 . HIS D 1 313 ? 161.539 123.294 105.329 1.00 26.56  ? 313 HIS D CE1 1 
ATOM   16565 N NE2 . HIS D 1 313 ? 162.585 123.932 105.865 1.00 37.15  ? 313 HIS D NE2 1 
ATOM   16566 N N   . ILE D 1 314 ? 162.765 122.293 109.858 1.00 19.37  ? 314 ILE D N   1 
ATOM   16567 C CA  . ILE D 1 314 ? 164.114 121.722 109.763 1.00 20.66  ? 314 ILE D CA  1 
ATOM   16568 C C   . ILE D 1 314 ? 164.103 120.307 110.361 1.00 19.02  ? 314 ILE D C   1 
ATOM   16569 O O   . ILE D 1 314 ? 164.587 119.385 109.678 1.00 29.86  ? 314 ILE D O   1 
ATOM   16570 C CB  . ILE D 1 314 ? 165.155 122.592 110.506 1.00 23.89  ? 314 ILE D CB  1 
ATOM   16571 C CG1 . ILE D 1 314 ? 165.256 123.999 109.915 1.00 23.14  ? 314 ILE D CG1 1 
ATOM   16572 C CG2 . ILE D 1 314 ? 166.520 121.882 110.543 1.00 19.76  ? 314 ILE D CG2 1 
ATOM   16573 C CD1 . ILE D 1 314 ? 166.200 124.913 110.662 1.00 22.05  ? 314 ILE D CD1 1 
ATOM   16574 N N   . LEU D 1 315 ? 163.570 120.141 111.576 1.00 23.75  ? 315 LEU D N   1 
ATOM   16575 C CA  . LEU D 1 315 ? 163.613 118.835 112.301 1.00 25.28  ? 315 LEU D CA  1 
ATOM   16576 C C   . LEU D 1 315 ? 162.880 117.717 111.550 1.00 27.09  ? 315 LEU D C   1 
ATOM   16577 O O   . LEU D 1 315 ? 163.343 116.582 111.617 1.00 25.44  ? 315 LEU D O   1 
ATOM   16578 C CB  . LEU D 1 315 ? 162.974 119.067 113.674 1.00 24.64  ? 315 LEU D CB  1 
ATOM   16579 C CG  . LEU D 1 315 ? 162.857 117.840 114.574 1.00 35.98  ? 315 LEU D CG  1 
ATOM   16580 C CD1 . LEU D 1 315 ? 164.232 117.374 115.028 1.00 32.44  ? 315 LEU D CD1 1 
ATOM   16581 C CD2 . LEU D 1 315 ? 161.976 118.149 115.774 1.00 25.32  ? 315 LEU D CD2 1 
ATOM   16582 N N   . GLN D 1 316 ? 161.797 117.994 110.826 1.00 33.59  ? 316 GLN D N   1 
ATOM   16583 C CA  . GLN D 1 316 ? 160.967 117.014 110.124 1.00 26.49  ? 316 GLN D CA  1 
ATOM   16584 C C   . GLN D 1 316 ? 161.142 117.020 108.593 1.00 21.29  ? 316 GLN D C   1 
ATOM   16585 O O   . GLN D 1 316 ? 160.317 116.452 107.878 1.00 32.62  ? 316 GLN D O   1 
ATOM   16586 C CB  . GLN D 1 316 ? 159.498 117.215 110.526 1.00 20.24  ? 316 GLN D CB  1 
ATOM   16587 C CG  . GLN D 1 316 ? 159.281 117.230 112.046 1.00 30.59  ? 316 GLN D CG  1 
ATOM   16588 C CD  . GLN D 1 316 ? 157.831 117.403 112.450 1.00 29.59  ? 316 GLN D CD  1 
ATOM   16589 O OE1 . GLN D 1 316 ? 156.952 117.731 111.668 1.00 32.37  ? 316 GLN D OE1 1 
ATOM   16590 N NE2 . GLN D 1 316 ? 157.530 117.203 113.708 1.00 24.62  ? 316 GLN D NE2 1 
ATOM   16591 N N   . ARG D 1 317 ? 162.179 117.704 108.090 1.00 22.22  ? 317 ARG D N   1 
ATOM   16592 C CA  . ARG D 1 317 ? 162.372 117.922 106.621 1.00 33.27  ? 317 ARG D CA  1 
ATOM   16593 C C   . ARG D 1 317 ? 162.634 116.639 105.827 1.00 30.60  ? 317 ARG D C   1 
ATOM   16594 O O   . ARG D 1 317 ? 163.468 115.829 106.275 1.00 32.73  ? 317 ARG D O   1 
ATOM   16595 C CB  . ARG D 1 317 ? 163.542 118.895 106.480 1.00 29.30  ? 317 ARG D CB  1 
ATOM   16596 C CG  . ARG D 1 317 ? 163.705 119.460 105.072 1.00 25.10  ? 317 ARG D CG  1 
ATOM   16597 C CD  . ARG D 1 317 ? 164.797 120.528 105.091 1.00 35.92  ? 317 ARG D CD  1 
ATOM   16598 N NE  . ARG D 1 317 ? 166.124 119.980 105.335 1.00 34.36  ? 317 ARG D NE  1 
ATOM   16599 C CZ  . ARG D 1 317 ? 166.689 119.876 106.533 1.00 28.56  ? 317 ARG D CZ  1 
ATOM   16600 N NH1 . ARG D 1 317 ? 167.901 119.365 106.653 1.00 30.45  ? 317 ARG D NH1 1 
ATOM   16601 N NH2 . ARG D 1 317 ? 166.039 120.287 107.608 1.00 40.48  ? 317 ARG D NH2 1 
ATOM   16602 N N   . GLU D 1 318 ? 161.947 116.468 104.694 1.00 34.63  ? 318 GLU D N   1 
ATOM   16603 C CA  . GLU D 1 318 ? 162.152 115.352 103.765 1.00 30.10  ? 318 GLU D CA  1 
ATOM   16604 C C   . GLU D 1 318 ? 162.162 115.794 102.291 1.00 36.37  ? 318 GLU D C   1 
ATOM   16605 O O   . GLU D 1 318 ? 161.369 116.642 101.887 1.00 38.19  ? 318 GLU D O   1 
ATOM   16606 C CB  . GLU D 1 318 ? 161.107 114.257 104.038 1.00 36.17  ? 318 GLU D CB  1 
ATOM   16607 C CG  . GLU D 1 318 ? 161.365 113.005 103.190 1.00 38.84  ? 318 GLU D CG  1 
ATOM   16608 C CD  . GLU D 1 318 ? 160.590 111.765 103.658 1.00 42.73  ? 318 GLU D CD  1 
ATOM   16609 O OE1 . GLU D 1 318 ? 159.541 111.906 104.325 1.00 46.32  ? 318 GLU D OE1 1 
ATOM   16610 O OE2 . GLU D 1 318 ? 161.008 110.644 103.298 1.00 38.33  ? 318 GLU D OE2 1 
ATOM   16611 N N   . PHE D 1 319 ? 163.035 115.184 101.483 1.00 44.55  ? 319 PHE D N   1 
ATOM   16612 C CA  . PHE D 1 319 ? 163.166 115.379 100.016 1.00 37.85  ? 319 PHE D CA  1 
ATOM   16613 C C   . PHE D 1 319 ? 163.432 114.031 99.305  1.00 46.51  ? 319 PHE D C   1 
ATOM   16614 O O   . PHE D 1 319 ? 163.700 113.030 99.998  1.00 47.26  ? 319 PHE D O   1 
ATOM   16615 C CB  . PHE D 1 319 ? 164.327 116.318 99.685  1.00 36.75  ? 319 PHE D CB  1 
ATOM   16616 C CG  . PHE D 1 319 ? 164.365 117.614 100.453 1.00 42.37  ? 319 PHE D CG  1 
ATOM   16617 C CD1 . PHE D 1 319 ? 163.471 118.633 100.171 1.00 45.23  ? 319 PHE D CD1 1 
ATOM   16618 C CD2 . PHE D 1 319 ? 165.313 117.823 101.441 1.00 41.95  ? 319 PHE D CD2 1 
ATOM   16619 C CE1 . PHE D 1 319 ? 163.513 119.828 100.871 1.00 40.34  ? 319 PHE D CE1 1 
ATOM   16620 C CE2 . PHE D 1 319 ? 165.357 119.018 102.140 1.00 40.43  ? 319 PHE D CE2 1 
ATOM   16621 C CZ  . PHE D 1 319 ? 164.457 120.019 101.853 1.00 40.88  ? 319 PHE D CZ  1 
ATOM   16622 N N   . SER D 1 320 ? 163.364 114.026 97.968  1.00 57.85  ? 320 SER D N   1 
ATOM   16623 C CA  . SER D 1 320 ? 163.530 112.850 97.087  1.00 56.28  ? 320 SER D CA  1 
ATOM   16624 C C   . SER D 1 320 ? 164.322 113.187 95.810  1.00 56.01  ? 320 SER D C   1 
ATOM   16625 O O   . SER D 1 320 ? 164.474 114.364 95.470  1.00 55.32  ? 320 SER D O   1 
ATOM   16626 C CB  . SER D 1 320 ? 162.155 112.268 96.754  1.00 53.75  ? 320 SER D CB  1 
ATOM   16627 O OG  . SER D 1 320 ? 161.342 113.225 96.106  1.00 58.82  ? 320 SER D OG  1 
ATOM   16628 N N   . GLY D 1 321 ? 164.877 112.195 95.121  1.00 57.85  ? 321 GLY D N   1 
ATOM   16629 C CA  . GLY D 1 321 ? 165.756 112.453 93.980  1.00 57.04  ? 321 GLY D CA  1 
ATOM   16630 C C   . GLY D 1 321 ? 167.068 113.117 94.420  1.00 57.26  ? 321 GLY D C   1 
ATOM   16631 O O   . GLY D 1 321 ? 167.719 112.603 95.334  1.00 58.67  ? 321 GLY D O   1 
ATOM   16632 N N   . PRO D 1 322 ? 167.491 114.241 93.814  1.00 56.12  ? 322 PRO D N   1 
ATOM   16633 C CA  . PRO D 1 322 ? 168.829 114.793 94.028  1.00 54.60  ? 322 PRO D CA  1 
ATOM   16634 C C   . PRO D 1 322 ? 169.034 115.380 95.431  1.00 53.71  ? 322 PRO D C   1 
ATOM   16635 O O   . PRO D 1 322 ? 170.144 115.367 95.955  1.00 54.93  ? 322 PRO D O   1 
ATOM   16636 C CB  . PRO D 1 322 ? 168.988 115.864 92.945  1.00 52.56  ? 322 PRO D CB  1 
ATOM   16637 C CG  . PRO D 1 322 ? 167.559 116.318 92.662  1.00 53.50  ? 322 PRO D CG  1 
ATOM   16638 C CD  . PRO D 1 322 ? 166.756 115.037 92.844  1.00 52.15  ? 322 PRO D CD  1 
ATOM   16639 N N   . TYR D 1 323 ? 167.961 115.881 96.052  1.00 48.59  ? 323 TYR D N   1 
ATOM   16640 C CA  . TYR D 1 323 ? 167.998 116.574 97.340  1.00 45.39  ? 323 TYR D CA  1 
ATOM   16641 C C   . TYR D 1 323 ? 167.728 115.678 98.550  1.00 49.38  ? 323 TYR D C   1 
ATOM   16642 O O   . TYR D 1 323 ? 167.751 116.159 99.674  1.00 49.70  ? 323 TYR D O   1 
ATOM   16643 C CB  . TYR D 1 323 ? 167.057 117.787 97.281  1.00 45.00  ? 323 TYR D CB  1 
ATOM   16644 C CG  . TYR D 1 323 ? 167.420 118.793 96.202  1.00 49.38  ? 323 TYR D CG  1 
ATOM   16645 C CD1 . TYR D 1 323 ? 168.735 119.296 96.106  1.00 48.18  ? 323 TYR D CD1 1 
ATOM   16646 C CD2 . TYR D 1 323 ? 166.438 119.229 95.294  1.00 47.60  ? 323 TYR D CD2 1 
ATOM   16647 C CE1 . TYR D 1 323 ? 169.066 120.218 95.098  1.00 46.48  ? 323 TYR D CE1 1 
ATOM   16648 C CE2 . TYR D 1 323 ? 166.764 120.160 94.293  1.00 45.79  ? 323 TYR D CE2 1 
ATOM   16649 C CZ  . TYR D 1 323 ? 168.078 120.653 94.193  1.00 50.01  ? 323 TYR D CZ  1 
ATOM   16650 O OH  . TYR D 1 323 ? 168.391 121.574 93.244  1.00 50.53  ? 323 TYR D OH  1 
ATOM   16651 N N   . GLN D 1 324 ? 167.511 114.378 98.359  1.00 48.14  ? 324 GLN D N   1 
ATOM   16652 C CA  . GLN D 1 324 ? 167.243 113.437 99.447  1.00 42.85  ? 324 GLN D CA  1 
ATOM   16653 C C   . GLN D 1 324 ? 168.272 113.497 100.601 1.00 44.68  ? 324 GLN D C   1 
ATOM   16654 O O   . GLN D 1 324 ? 167.826 113.507 101.749 1.00 43.91  ? 324 GLN D O   1 
ATOM   16655 C CB  . GLN D 1 324 ? 167.039 112.036 98.849  1.00 46.74  ? 324 GLN D CB  1 
ATOM   16656 C CG  . GLN D 1 324 ? 166.495 110.991 99.837  1.00 47.44  ? 324 GLN D CG  1 
ATOM   16657 C CD  . GLN D 1 324 ? 167.560 110.141 100.520 1.00 47.99  ? 324 GLN D CD  1 
ATOM   16658 O OE1 . GLN D 1 324 ? 168.748 110.415 100.495 1.00 50.34  ? 324 GLN D OE1 1 
ATOM   16659 N NE2 . GLN D 1 324 ? 167.165 109.063 101.151 1.00 46.16  ? 324 GLN D NE2 1 
ATOM   16660 N N   . PRO D 1 325 ? 169.593 113.662 100.372 1.00 46.69  ? 325 PRO D N   1 
ATOM   16661 C CA  . PRO D 1 325 ? 170.573 113.836 101.448 1.00 45.60  ? 325 PRO D CA  1 
ATOM   16662 C C   . PRO D 1 325 ? 170.364 115.078 102.330 1.00 41.63  ? 325 PRO D C   1 
ATOM   16663 O O   . PRO D 1 325 ? 170.853 115.117 103.456 1.00 45.69  ? 325 PRO D O   1 
ATOM   16664 C CB  . PRO D 1 325 ? 171.940 113.909 100.760 1.00 45.82  ? 325 PRO D CB  1 
ATOM   16665 C CG  . PRO D 1 325 ? 171.717 113.194 99.439  1.00 45.17  ? 325 PRO D CG  1 
ATOM   16666 C CD  . PRO D 1 325 ? 170.285 113.576 99.097  1.00 38.94  ? 325 PRO D CD  1 
ATOM   16667 N N   . LEU D 1 326 ? 169.632 116.095 101.872 1.00 41.86  ? 326 LEU D N   1 
ATOM   16668 C CA  . LEU D 1 326 ? 169.277 117.263 102.684 1.00 36.72  ? 326 LEU D CA  1 
ATOM   16669 C C   . LEU D 1 326 ? 168.128 116.982 103.667 1.00 38.91  ? 326 LEU D C   1 
ATOM   16670 O O   . LEU D 1 326 ? 167.759 117.856 104.441 1.00 46.61  ? 326 LEU D O   1 
ATOM   16671 C CB  . LEU D 1 326 ? 168.932 118.456 101.774 1.00 40.92  ? 326 LEU D CB  1 
ATOM   16672 C CG  . LEU D 1 326 ? 170.057 118.982 100.875 1.00 38.39  ? 326 LEU D CG  1 
ATOM   16673 C CD1 . LEU D 1 326 ? 169.460 120.007 99.913  1.00 38.11  ? 326 LEU D CD1 1 
ATOM   16674 C CD2 . LEU D 1 326 ? 171.151 119.647 101.698 1.00 36.75  ? 326 LEU D CD2 1 
ATOM   16675 N N   . SER D 1 327 ? 167.527 115.796 103.657 1.00 36.25  ? 327 SER D N   1 
ATOM   16676 C CA  . SER D 1 327 ? 166.466 115.413 104.594 1.00 29.97  ? 327 SER D CA  1 
ATOM   16677 C C   . SER D 1 327 ? 166.991 115.218 106.017 1.00 31.75  ? 327 SER D C   1 
ATOM   16678 O O   . SER D 1 327 ? 168.122 114.784 106.218 1.00 32.83  ? 327 SER D O   1 
ATOM   16679 C CB  . SER D 1 327 ? 165.792 114.113 104.156 1.00 32.56  ? 327 SER D CB  1 
ATOM   16680 O OG  . SER D 1 327 ? 165.413 114.167 102.804 1.00 36.29  ? 327 SER D OG  1 
ATOM   16681 N N   . ARG D 1 328 ? 166.141 115.479 107.015 1.00 31.08  ? 328 ARG D N   1 
ATOM   16682 C CA  . ARG D 1 328 ? 166.287 114.990 108.395 1.00 23.68  ? 328 ARG D CA  1 
ATOM   16683 C C   . ARG D 1 328 ? 165.289 113.882 108.741 1.00 28.08  ? 328 ARG D C   1 
ATOM   16684 O O   . ARG D 1 328 ? 165.558 113.099 109.637 1.00 25.13  ? 328 ARG D O   1 
ATOM   16685 C CB  . ARG D 1 328 ? 166.167 116.147 109.397 1.00 25.11  ? 328 ARG D CB  1 
ATOM   16686 C CG  . ARG D 1 328 ? 167.371 117.095 109.358 1.00 19.59  ? 328 ARG D CG  1 
ATOM   16687 C CD  . ARG D 1 328 ? 167.452 117.993 110.598 1.00 29.13  ? 328 ARG D CD  1 
ATOM   16688 N NE  . ARG D 1 328 ? 167.826 117.245 111.812 1.00 24.99  ? 328 ARG D NE  1 
ATOM   16689 C CZ  . ARG D 1 328 ? 169.033 117.118 112.313 1.00 25.27  ? 328 ARG D CZ  1 
ATOM   16690 N NH1 . ARG D 1 328 ? 169.252 116.297 113.285 1.00 24.88  ? 328 ARG D NH1 1 
ATOM   16691 N NH2 . ARG D 1 328 ? 170.051 117.770 111.846 1.00 31.15  ? 328 ARG D NH2 1 
ATOM   16692 N N   . LYS D 1 329 ? 164.169 113.790 108.031 1.00 28.15  ? 329 LYS D N   1 
ATOM   16693 C CA  . LYS D 1 329 ? 163.182 112.715 108.124 1.00 25.81  ? 329 LYS D CA  1 
ATOM   16694 C C   . LYS D 1 329 ? 163.264 111.857 106.866 1.00 24.79  ? 329 LYS D C   1 
ATOM   16695 O O   . LYS D 1 329 ? 163.289 112.390 105.768 1.00 33.60  ? 329 LYS D O   1 
ATOM   16696 C CB  . LYS D 1 329 ? 161.801 113.350 108.306 1.00 22.68  ? 329 LYS D CB  1 
ATOM   16697 C CG  . LYS D 1 329 ? 160.671 112.334 108.478 1.00 18.43  ? 329 LYS D CG  1 
ATOM   16698 C CD  . LYS D 1 329 ? 159.330 113.059 108.527 1.00 23.14  ? 329 LYS D CD  1 
ATOM   16699 C CE  . LYS D 1 329 ? 158.191 112.060 108.713 1.00 24.53  ? 329 LYS D CE  1 
ATOM   16700 N NZ  . LYS D 1 329 ? 156.881 112.740 108.812 1.00 28.35  ? 329 LYS D NZ  1 
ATOM   16701 N N   . PHE D 1 330 ? 163.280 110.541 107.019 1.00 25.43  ? 330 PHE D N   1 
ATOM   16702 C CA  . PHE D 1 330 ? 163.257 109.573 105.928 1.00 20.80  ? 330 PHE D CA  1 
ATOM   16703 C C   . PHE D 1 330 ? 162.086 108.614 106.123 1.00 26.90  ? 330 PHE D C   1 
ATOM   16704 O O   . PHE D 1 330 ? 162.057 107.896 107.117 1.00 34.63  ? 330 PHE D O   1 
ATOM   16705 C CB  . PHE D 1 330 ? 164.588 108.809 105.890 1.00 24.02  ? 330 PHE D CB  1 
ATOM   16706 C CG  . PHE D 1 330 ? 165.814 109.695 105.819 1.00 35.48  ? 330 PHE D CG  1 
ATOM   16707 C CD1 . PHE D 1 330 ? 166.406 110.187 106.998 1.00 36.04  ? 330 PHE D CD1 1 
ATOM   16708 C CD2 . PHE D 1 330 ? 166.332 110.065 104.570 1.00 29.88  ? 330 PHE D CD2 1 
ATOM   16709 C CE1 . PHE D 1 330 ? 167.494 111.065 106.923 1.00 32.97  ? 330 PHE D CE1 1 
ATOM   16710 C CE2 . PHE D 1 330 ? 167.433 110.926 104.493 1.00 29.71  ? 330 PHE D CE2 1 
ATOM   16711 C CZ  . PHE D 1 330 ? 168.002 111.435 105.669 1.00 33.65  ? 330 PHE D CZ  1 
ATOM   16712 N N   . THR D 1 331 ? 161.130 108.547 105.205 1.00 37.38  ? 331 THR D N   1 
ATOM   16713 C CA  . THR D 1 331 ? 160.099 107.500 105.247 1.00 27.60  ? 331 THR D CA  1 
ATOM   16714 C C   . THR D 1 331 ? 160.728 106.126 105.019 1.00 26.87  ? 331 THR D C   1 
ATOM   16715 O O   . THR D 1 331 ? 161.501 105.925 104.088 1.00 35.26  ? 331 THR D O   1 
ATOM   16716 C CB  . THR D 1 331 ? 158.944 107.787 104.284 1.00 30.41  ? 331 THR D CB  1 
ATOM   16717 O OG1 . THR D 1 331 ? 157.908 106.880 104.551 1.00 30.29  ? 331 THR D OG1 1 
ATOM   16718 C CG2 . THR D 1 331 ? 159.271 107.643 102.800 1.00 39.58  ? 331 THR D CG2 1 
ATOM   16719 N N   . GLU D 1 332 ? 160.447 105.174 105.897 1.00 33.92  ? 332 GLU D N   1 
ATOM   16720 C CA  . GLU D 1 332 ? 160.972 103.815 105.824 1.00 32.38  ? 332 GLU D CA  1 
ATOM   16721 C C   . GLU D 1 332 ? 159.977 102.876 105.138 1.00 34.65  ? 332 GLU D C   1 
ATOM   16722 O O   . GLU D 1 332 ? 160.347 102.139 104.227 1.00 41.90  ? 332 GLU D O   1 
ATOM   16723 C CB  . GLU D 1 332 ? 161.321 103.347 107.237 1.00 32.51  ? 332 GLU D CB  1 
ATOM   16724 C CG  . GLU D 1 332 ? 162.088 102.024 107.215 1.00 37.65  ? 332 GLU D CG  1 
ATOM   16725 C CD  . GLU D 1 332 ? 162.623 101.669 108.602 1.00 45.11  ? 332 GLU D CD  1 
ATOM   16726 O OE1 . GLU D 1 332 ? 161.900 101.865 109.595 1.00 41.83  ? 332 GLU D OE1 1 
ATOM   16727 O OE2 . GLU D 1 332 ? 163.762 101.157 108.720 1.00 48.48  ? 332 GLU D OE2 1 
ATOM   16728 N N   . TRP D 1 333 ? 158.705 102.952 105.529 1.00 34.79  ? 333 TRP D N   1 
ATOM   16729 C CA  . TRP D 1 333 ? 157.570 102.379 104.807 1.00 30.29  ? 333 TRP D CA  1 
ATOM   16730 C C   . TRP D 1 333 ? 156.266 103.089 105.174 1.00 30.89  ? 333 TRP D C   1 
ATOM   16731 O O   . TRP D 1 333 ? 156.148 103.724 106.220 1.00 35.80  ? 333 TRP D O   1 
ATOM   16732 C CB  . TRP D 1 333 ? 157.466 100.863 105.033 1.00 26.23  ? 333 TRP D CB  1 
ATOM   16733 C CG  . TRP D 1 333 ? 157.312 100.361 106.435 1.00 28.35  ? 333 TRP D CG  1 
ATOM   16734 C CD1 . TRP D 1 333 ? 158.326 99.918  107.207 1.00 30.22  ? 333 TRP D CD1 1 
ATOM   16735 C CD2 . TRP D 1 333 ? 156.100 100.186 107.232 1.00 33.81  ? 333 TRP D CD2 1 
ATOM   16736 N NE1 . TRP D 1 333 ? 157.830 99.463  108.406 1.00 33.66  ? 333 TRP D NE1 1 
ATOM   16737 C CE2 . TRP D 1 333 ? 156.461 99.559  108.461 1.00 32.15  ? 333 TRP D CE2 1 
ATOM   16738 C CE3 . TRP D 1 333 ? 154.729 100.462 107.044 1.00 33.16  ? 333 TRP D CE3 1 
ATOM   16739 C CZ2 . TRP D 1 333 ? 155.519 99.193  109.428 1.00 27.43  ? 333 TRP D CZ2 1 
ATOM   16740 C CZ3 . TRP D 1 333 ? 153.781 100.147 108.033 1.00 32.88  ? 333 TRP D CZ3 1 
ATOM   16741 C CH2 . TRP D 1 333 ? 154.171 99.497  109.215 1.00 32.98  ? 333 TRP D CH2 1 
ATOM   16742 N N   . CYS D 1 334 ? 155.271 102.987 104.300 1.00 39.47  ? 334 CYS D N   1 
ATOM   16743 C CA  . CYS D 1 334 ? 153.940 103.542 104.494 1.00 33.46  ? 334 CYS D CA  1 
ATOM   16744 C C   . CYS D 1 334 ? 152.896 102.520 104.031 1.00 35.78  ? 334 CYS D C   1 
ATOM   16745 O O   . CYS D 1 334 ? 152.995 101.997 102.925 1.00 44.07  ? 334 CYS D O   1 
ATOM   16746 C CB  . CYS D 1 334 ? 153.894 104.868 103.727 1.00 33.36  ? 334 CYS D CB  1 
ATOM   16747 S SG  . CYS D 1 334 ? 152.318 105.711 103.963 1.00 58.05  ? 334 CYS D SG  1 
ATOM   16748 N N   . TYR D 1 335 ? 151.897 102.221 104.856 1.00 30.38  ? 335 TYR D N   1 
ATOM   16749 C CA  . TYR D 1 335 ? 150.883 101.206 104.572 1.00 30.98  ? 335 TYR D CA  1 
ATOM   16750 C C   . TYR D 1 335 ? 149.563 101.612 105.227 1.00 34.11  ? 335 TYR D C   1 
ATOM   16751 O O   . TYR D 1 335 ? 149.423 101.611 106.449 1.00 36.00  ? 335 TYR D O   1 
ATOM   16752 C CB  . TYR D 1 335 ? 151.371 99.827  105.034 1.00 34.36  ? 335 TYR D CB  1 
ATOM   16753 C CG  . TYR D 1 335 ? 150.464 98.670  104.673 1.00 33.63  ? 335 TYR D CG  1 
ATOM   16754 C CD1 . TYR D 1 335 ? 149.425 98.292  105.537 1.00 34.68  ? 335 TYR D CD1 1 
ATOM   16755 C CD2 . TYR D 1 335 ? 150.675 97.948  103.487 1.00 34.02  ? 335 TYR D CD2 1 
ATOM   16756 C CE1 . TYR D 1 335 ? 148.576 97.217  105.203 1.00 29.85  ? 335 TYR D CE1 1 
ATOM   16757 C CE2 . TYR D 1 335 ? 149.819 96.886  103.138 1.00 35.97  ? 335 TYR D CE2 1 
ATOM   16758 C CZ  . TYR D 1 335 ? 148.767 96.520  103.997 1.00 36.22  ? 335 TYR D CZ  1 
ATOM   16759 O OH  . TYR D 1 335 ? 147.949 95.490  103.668 1.00 36.21  ? 335 TYR D OH  1 
ATOM   16760 N N   . GLY D 1 336 ? 148.591 102.017 104.418 1.00 37.97  ? 336 GLY D N   1 
ATOM   16761 C CA  . GLY D 1 336 ? 147.338 102.569 104.904 1.00 29.88  ? 336 GLY D CA  1 
ATOM   16762 C C   . GLY D 1 336 ? 147.571 103.825 105.753 1.00 31.06  ? 336 GLY D C   1 
ATOM   16763 O O   . GLY D 1 336 ? 148.376 104.676 105.372 1.00 40.15  ? 336 GLY D O   1 
ATOM   16764 N N   . PRO D 1 337 ? 146.918 103.960 106.918 1.00 32.92  ? 337 PRO D N   1 
ATOM   16765 C CA  . PRO D 1 337 ? 147.063 105.115 107.801 1.00 32.92  ? 337 PRO D CA  1 
ATOM   16766 C C   . PRO D 1 337 ? 148.401 105.164 108.552 1.00 35.80  ? 337 PRO D C   1 
ATOM   16767 O O   . PRO D 1 337 ? 148.627 106.104 109.305 1.00 36.84  ? 337 PRO D O   1 
ATOM   16768 C CB  . PRO D 1 337 ? 145.875 105.015 108.753 1.00 29.27  ? 337 PRO D CB  1 
ATOM   16769 C CG  . PRO D 1 337 ? 145.655 103.510 108.869 1.00 31.07  ? 337 PRO D CG  1 
ATOM   16770 C CD  . PRO D 1 337 ? 145.981 103.009 107.476 1.00 30.80  ? 337 PRO D CD  1 
ATOM   16771 N N   . VAL D 1 338 ? 149.280 104.173 108.380 1.00 36.91  ? 338 VAL D N   1 
ATOM   16772 C CA  . VAL D 1 338 ? 150.544 104.039 109.108 1.00 32.08  ? 338 VAL D CA  1 
ATOM   16773 C C   . VAL D 1 338 ? 151.723 104.511 108.257 1.00 34.98  ? 338 VAL D C   1 
ATOM   16774 O O   . VAL D 1 338 ? 151.949 104.005 107.161 1.00 35.76  ? 338 VAL D O   1 
ATOM   16775 C CB  . VAL D 1 338 ? 150.771 102.584 109.560 1.00 36.95  ? 338 VAL D CB  1 
ATOM   16776 C CG1 . VAL D 1 338 ? 151.989 102.478 110.485 1.00 32.48  ? 338 VAL D CG1 1 
ATOM   16777 C CG2 . VAL D 1 338 ? 149.545 102.020 110.289 1.00 33.46  ? 338 VAL D CG2 1 
ATOM   16778 N N   . ARG D 1 339 ? 152.507 105.449 108.791 1.00 35.48  ? 339 ARG D N   1 
ATOM   16779 C CA  . ARG D 1 339 ? 153.812 105.886 108.272 1.00 27.93  ? 339 ARG D CA  1 
ATOM   16780 C C   . ARG D 1 339 ? 154.890 105.541 109.281 1.00 27.60  ? 339 ARG D C   1 
ATOM   16781 O O   . ARG D 1 339 ? 154.830 105.994 110.416 1.00 33.31  ? 339 ARG D O   1 
ATOM   16782 C CB  . ARG D 1 339 ? 153.796 107.398 108.013 1.00 34.42  ? 339 ARG D CB  1 
ATOM   16783 C CG  . ARG D 1 339 ? 153.024 107.750 106.746 1.00 37.98  ? 339 ARG D CG  1 
ATOM   16784 C CD  . ARG D 1 339 ? 152.975 109.261 106.521 1.00 36.89  ? 339 ARG D CD  1 
ATOM   16785 N NE  . ARG D 1 339 ? 152.333 109.587 105.234 1.00 40.28  ? 339 ARG D NE  1 
ATOM   16786 C CZ  . ARG D 1 339 ? 152.912 109.682 104.056 1.00 46.29  ? 339 ARG D CZ  1 
ATOM   16787 N NH1 . ARG D 1 339 ? 152.206 109.953 102.998 1.00 44.76  ? 339 ARG D NH1 1 
ATOM   16788 N NH2 . ARG D 1 339 ? 154.196 109.529 103.891 1.00 44.45  ? 339 ARG D NH2 1 
ATOM   16789 N N   . VAL D 1 340 ? 155.910 104.802 108.877 1.00 27.34  ? 340 VAL D N   1 
ATOM   16790 C CA  . VAL D 1 340 ? 157.109 104.589 109.688 1.00 26.58  ? 340 VAL D CA  1 
ATOM   16791 C C   . VAL D 1 340 ? 158.243 105.411 109.104 1.00 28.65  ? 340 VAL D C   1 
ATOM   16792 O O   . VAL D 1 340 ? 158.552 105.293 107.926 1.00 28.79  ? 340 VAL D O   1 
ATOM   16793 C CB  . VAL D 1 340 ? 157.451 103.100 109.804 1.00 25.84  ? 340 VAL D CB  1 
ATOM   16794 C CG1 . VAL D 1 340 ? 158.699 102.891 110.661 1.00 24.74  ? 340 VAL D CG1 1 
ATOM   16795 C CG2 . VAL D 1 340 ? 156.280 102.367 110.454 1.00 24.82  ? 340 VAL D CG2 1 
ATOM   16796 N N   . SER D 1 341 ? 158.846 106.272 109.915 1.00 32.48  ? 341 SER D N   1 
ATOM   16797 C CA  . SER D 1 341 ? 159.916 107.179 109.501 1.00 25.77  ? 341 SER D CA  1 
ATOM   16798 C C   . SER D 1 341 ? 161.132 107.049 110.395 1.00 24.67  ? 341 SER D C   1 
ATOM   16799 O O   . SER D 1 341 ? 161.006 106.841 111.593 1.00 27.60  ? 341 SER D O   1 
ATOM   16800 C CB  . SER D 1 341 ? 159.453 108.632 109.524 1.00 30.97  ? 341 SER D CB  1 
ATOM   16801 O OG  . SER D 1 341 ? 158.353 108.828 108.666 1.00 35.52  ? 341 SER D OG  1 
ATOM   16802 N N   . LEU D 1 342 ? 162.309 107.257 109.827 1.00 25.72  ? 342 LEU D N   1 
ATOM   16803 C CA  . LEU D 1 342 ? 163.547 107.499 110.554 1.00 25.86  ? 342 LEU D CA  1 
ATOM   16804 C C   . LEU D 1 342 ? 163.790 109.006 110.641 1.00 22.68  ? 342 LEU D C   1 
ATOM   16805 O O   . LEU D 1 342 ? 163.783 109.689 109.625 1.00 25.10  ? 342 LEU D O   1 
ATOM   16806 C CB  . LEU D 1 342 ? 164.706 106.820 109.814 1.00 29.61  ? 342 LEU D CB  1 
ATOM   16807 C CG  . LEU D 1 342 ? 164.651 105.288 109.770 1.00 27.78  ? 342 LEU D CG  1 
ATOM   16808 C CD1 . LEU D 1 342 ? 165.805 104.768 108.915 1.00 28.52  ? 342 LEU D CD1 1 
ATOM   16809 C CD2 . LEU D 1 342 ? 164.757 104.676 111.161 1.00 24.13  ? 342 LEU D CD2 1 
ATOM   16810 N N   . TYR D 1 343 ? 164.028 109.529 111.835 1.00 30.00  ? 343 TYR D N   1 
ATOM   16811 C CA  . TYR D 1 343 ? 164.449 110.911 112.058 1.00 20.08  ? 343 TYR D CA  1 
ATOM   16812 C C   . TYR D 1 343 ? 165.909 110.983 112.490 1.00 22.39  ? 343 TYR D C   1 
ATOM   16813 O O   . TYR D 1 343 ? 166.318 110.296 113.417 1.00 27.10  ? 343 TYR D O   1 
ATOM   16814 C CB  . TYR D 1 343 ? 163.587 111.567 113.127 1.00 15.35  ? 343 TYR D CB  1 
ATOM   16815 C CG  . TYR D 1 343 ? 162.164 111.868 112.726 1.00 17.42  ? 343 TYR D CG  1 
ATOM   16816 C CD1 . TYR D 1 343 ? 161.150 110.913 112.901 1.00 16.41  ? 343 TYR D CD1 1 
ATOM   16817 C CD2 . TYR D 1 343 ? 161.852 113.147 112.240 1.00 14.89  ? 343 TYR D CD2 1 
ATOM   16818 C CE1 . TYR D 1 343 ? 159.812 111.255 112.628 1.00 12.58  ? 343 TYR D CE1 1 
ATOM   16819 C CE2 . TYR D 1 343 ? 160.521 113.488 111.981 1.00 14.83  ? 343 TYR D CE2 1 
ATOM   16820 C CZ  . TYR D 1 343 ? 159.495 112.552 112.191 1.00 21.08  ? 343 TYR D CZ  1 
ATOM   16821 O OH  . TYR D 1 343 ? 158.210 112.911 111.952 1.00 32.08  ? 343 TYR D OH  1 
ATOM   16822 N N   . ASP D 1 344 ? 166.679 111.851 111.858 1.00 25.80  ? 344 ASP D N   1 
ATOM   16823 C CA  . ASP D 1 344 ? 168.065 112.169 112.185 1.00 27.02  ? 344 ASP D CA  1 
ATOM   16824 C C   . ASP D 1 344 ? 168.179 112.871 113.554 1.00 27.95  ? 344 ASP D C   1 
ATOM   16825 O O   . ASP D 1 344 ? 167.668 113.977 113.744 1.00 35.52  ? 344 ASP D O   1 
ATOM   16826 C CB  . ASP D 1 344 ? 168.579 113.033 111.026 1.00 22.53  ? 344 ASP D CB  1 
ATOM   16827 C CG  . ASP D 1 344 ? 170.026 113.503 111.125 1.00 30.51  ? 344 ASP D CG  1 
ATOM   16828 O OD1 . ASP D 1 344 ? 170.675 113.327 112.175 1.00 38.11  ? 344 ASP D OD1 1 
ATOM   16829 O OD2 . ASP D 1 344 ? 170.506 114.084 110.130 1.00 31.30  ? 344 ASP D OD2 1 
ATOM   16830 N N   . LEU D 1 345 ? 168.864 112.240 114.508 1.00 20.36  ? 345 LEU D N   1 
ATOM   16831 C CA  . LEU D 1 345 ? 169.068 112.754 115.865 1.00 21.61  ? 345 LEU D CA  1 
ATOM   16832 C C   . LEU D 1 345 ? 170.382 113.514 116.084 1.00 24.73  ? 345 LEU D C   1 
ATOM   16833 O O   . LEU D 1 345 ? 170.678 113.882 117.218 1.00 36.33  ? 345 LEU D O   1 
ATOM   16834 C CB  . LEU D 1 345 ? 168.963 111.596 116.871 1.00 28.45  ? 345 LEU D CB  1 
ATOM   16835 C CG  . LEU D 1 345 ? 167.585 110.949 117.039 1.00 25.07  ? 345 LEU D CG  1 
ATOM   16836 C CD1 . LEU D 1 345 ? 167.643 110.127 118.326 1.00 24.04  ? 345 LEU D CD1 1 
ATOM   16837 C CD2 . LEU D 1 345 ? 166.451 111.962 117.170 1.00 30.03  ? 345 LEU D CD2 1 
ATOM   16838 N N   . SER D 1 346 ? 171.183 113.759 115.048 1.00 30.17  ? 346 SER D N   1 
ATOM   16839 C CA  . SER D 1 346 ? 172.596 114.188 115.135 1.00 36.47  ? 346 SER D CA  1 
ATOM   16840 C C   . SER D 1 346 ? 172.921 115.289 116.160 1.00 43.13  ? 346 SER D C   1 
ATOM   16841 O O   . SER D 1 346 ? 173.816 115.112 116.988 1.00 46.70  ? 346 SER D O   1 
ATOM   16842 C CB  . SER D 1 346 ? 173.099 114.603 113.749 1.00 28.64  ? 346 SER D CB  1 
ATOM   16843 O OG  . SER D 1 346 ? 172.114 115.336 113.053 1.00 36.15  ? 346 SER D OG  1 
ATOM   16844 N N   . SER D 1 347 ? 172.189 116.402 116.144 1.00 28.09  ? 347 SER D N   1 
ATOM   16845 C CA  . SER D 1 347 ? 172.339 117.508 117.107 1.00 24.99  ? 347 SER D CA  1 
ATOM   16846 C C   . SER D 1 347 ? 171.181 117.619 118.112 1.00 28.30  ? 347 SER D C   1 
ATOM   16847 O O   . SER D 1 347 ? 171.038 118.617 118.817 1.00 27.09  ? 347 SER D O   1 
ATOM   16848 C CB  . SER D 1 347 ? 172.562 118.804 116.329 1.00 27.98  ? 347 SER D CB  1 
ATOM   16849 O OG  . SER D 1 347 ? 171.518 119.012 115.401 1.00 38.89  ? 347 SER D OG  1 
ATOM   16850 N N   . VAL D 1 348 ? 170.337 116.589 118.185 1.00 32.11  ? 348 VAL D N   1 
ATOM   16851 C CA  . VAL D 1 348 ? 169.100 116.549 118.967 1.00 26.66  ? 348 VAL D CA  1 
ATOM   16852 C C   . VAL D 1 348 ? 169.261 115.781 120.274 1.00 28.55  ? 348 VAL D C   1 
ATOM   16853 O O   . VAL D 1 348 ? 168.888 116.291 121.326 1.00 27.33  ? 348 VAL D O   1 
ATOM   16854 C CB  . VAL D 1 348 ? 167.932 116.010 118.123 1.00 29.12  ? 348 VAL D CB  1 
ATOM   16855 C CG1 . VAL D 1 348 ? 166.640 115.890 118.929 1.00 28.49  ? 348 VAL D CG1 1 
ATOM   16856 C CG2 . VAL D 1 348 ? 167.644 116.919 116.928 1.00 18.74  ? 348 VAL D CG2 1 
ATOM   16857 N N   . ASP D 1 349 ? 169.817 114.573 120.221 1.00 34.25  ? 349 ASP D N   1 
ATOM   16858 C CA  . ASP D 1 349 ? 169.947 113.695 121.385 1.00 35.97  ? 349 ASP D CA  1 
ATOM   16859 C C   . ASP D 1 349 ? 170.862 114.308 122.462 1.00 36.18  ? 349 ASP D C   1 
ATOM   16860 O O   . ASP D 1 349 ? 171.928 114.847 122.168 1.00 44.84  ? 349 ASP D O   1 
ATOM   16861 C CB  . ASP D 1 349 ? 170.432 112.316 120.920 1.00 34.90  ? 349 ASP D CB  1 
ATOM   16862 C CG  . ASP D 1 349 ? 170.463 111.245 122.019 1.00 44.47  ? 349 ASP D CG  1 
ATOM   16863 O OD1 . ASP D 1 349 ? 169.810 111.429 123.074 1.00 41.19  ? 349 ASP D OD1 1 
ATOM   16864 O OD2 . ASP D 1 349 ? 171.155 110.231 121.801 1.00 49.03  ? 349 ASP D OD2 1 
ATOM   16865 N N   . SER D 1 350 ? 170.453 114.209 123.723 1.00 33.59  ? 350 SER D N   1 
ATOM   16866 C CA  . SER D 1 350 ? 171.129 114.737 124.914 1.00 32.69  ? 350 SER D CA  1 
ATOM   16867 C C   . SER D 1 350 ? 172.419 114.003 125.306 1.00 36.35  ? 350 SER D C   1 
ATOM   16868 O O   . SER D 1 350 ? 173.096 114.411 126.250 1.00 39.80  ? 350 SER D O   1 
ATOM   16869 C CB  . SER D 1 350 ? 170.133 114.706 126.069 1.00 34.43  ? 350 SER D CB  1 
ATOM   16870 O OG  . SER D 1 350 ? 169.583 113.415 126.191 1.00 41.87  ? 350 SER D OG  1 
ATOM   16871 N N   . TRP D 1 351 ? 172.795 112.943 124.587 1.00 39.40  ? 351 TRP D N   1 
ATOM   16872 C CA  . TRP D 1 351 ? 174.118 112.323 124.671 1.00 39.52  ? 351 TRP D CA  1 
ATOM   16873 C C   . TRP D 1 351 ? 175.239 113.302 124.306 1.00 43.73  ? 351 TRP D C   1 
ATOM   16874 O O   . TRP D 1 351 ? 176.304 113.279 124.914 1.00 44.59  ? 351 TRP D O   1 
ATOM   16875 C CB  . TRP D 1 351 ? 174.134 111.103 123.747 1.00 41.65  ? 351 TRP D CB  1 
ATOM   16876 C CG  . TRP D 1 351 ? 175.461 110.442 123.559 1.00 46.52  ? 351 TRP D CG  1 
ATOM   16877 C CD1 . TRP D 1 351 ? 175.985 109.480 124.347 1.00 42.19  ? 351 TRP D CD1 1 
ATOM   16878 C CD2 . TRP D 1 351 ? 176.471 110.706 122.536 1.00 44.75  ? 351 TRP D CD2 1 
ATOM   16879 N NE1 . TRP D 1 351 ? 177.230 109.114 123.880 1.00 42.79  ? 351 TRP D NE1 1 
ATOM   16880 C CE2 . TRP D 1 351 ? 177.584 109.843 122.766 1.00 43.02  ? 351 TRP D CE2 1 
ATOM   16881 C CE3 . TRP D 1 351 ? 176.541 111.565 121.421 1.00 38.80  ? 351 TRP D CE3 1 
ATOM   16882 C CZ2 . TRP D 1 351 ? 178.719 109.851 121.947 1.00 42.38  ? 351 TRP D CZ2 1 
ATOM   16883 C CZ3 . TRP D 1 351 ? 177.681 111.591 120.601 1.00 43.16  ? 351 TRP D CZ3 1 
ATOM   16884 C CH2 . TRP D 1 351 ? 178.769 110.742 120.863 1.00 46.16  ? 351 TRP D CH2 1 
ATOM   16885 N N   . GLU D 1 352 ? 174.996 114.182 123.335 1.00 46.79  ? 352 GLU D N   1 
ATOM   16886 C CA  . GLU D 1 352 ? 175.928 115.229 122.918 1.00 41.40  ? 352 GLU D CA  1 
ATOM   16887 C C   . GLU D 1 352 ? 175.753 116.509 123.751 1.00 43.03  ? 352 GLU D C   1 
ATOM   16888 O O   . GLU D 1 352 ? 174.649 116.876 124.154 1.00 42.01  ? 352 GLU D O   1 
ATOM   16889 C CB  . GLU D 1 352 ? 175.737 115.470 121.409 1.00 45.07  ? 352 GLU D CB  1 
ATOM   16890 C CG  . GLU D 1 352 ? 176.648 116.502 120.741 1.00 46.36  ? 352 GLU D CG  1 
ATOM   16891 C CD  . GLU D 1 352 ? 178.148 116.204 120.891 1.00 53.21  ? 352 GLU D CD  1 
ATOM   16892 O OE1 . GLU D 1 352 ? 178.657 116.208 122.035 1.00 51.00  ? 352 GLU D OE1 1 
ATOM   16893 O OE2 . GLU D 1 352 ? 178.820 116.000 119.860 1.00 52.49  ? 352 GLU D OE2 1 
ATOM   16894 N N   . LYS D 1 353 ? 176.847 117.227 124.000 1.00 45.08  ? 353 LYS D N   1 
ATOM   16895 C CA  . LYS D 1 353 ? 176.833 118.515 124.704 1.00 46.63  ? 353 LYS D CA  1 
ATOM   16896 C C   . LYS D 1 353 ? 176.039 119.563 123.912 1.00 47.55  ? 353 LYS D C   1 
ATOM   16897 O O   . LYS D 1 353 ? 176.181 119.655 122.694 1.00 43.78  ? 353 LYS D O   1 
ATOM   16898 C CB  . LYS D 1 353 ? 178.287 118.959 124.934 1.00 46.56  ? 353 LYS D CB  1 
ATOM   16899 C CG  . LYS D 1 353 ? 178.407 120.224 125.786 1.00 49.58  ? 353 LYS D CG  1 
ATOM   16900 C CD  . LYS D 1 353 ? 179.856 120.670 125.933 1.00 49.77  ? 353 LYS D CD  1 
ATOM   16901 C CE  . LYS D 1 353 ? 179.949 121.988 126.685 1.00 51.18  ? 353 LYS D CE  1 
ATOM   16902 N NZ  . LYS D 1 353 ? 181.325 122.493 126.770 1.00 49.38  ? 353 LYS D NZ  1 
ATOM   16903 N N   . ASN D 1 354 ? 175.266 120.407 124.601 1.00 40.45  ? 354 ASN D N   1 
ATOM   16904 C CA  . ASN D 1 354 ? 174.567 121.555 124.010 1.00 34.00  ? 354 ASN D CA  1 
ATOM   16905 C C   . ASN D 1 354 ? 173.607 121.146 122.872 1.00 33.99  ? 354 ASN D C   1 
ATOM   16906 O O   . ASN D 1 354 ? 173.590 121.749 121.803 1.00 45.33  ? 354 ASN D O   1 
ATOM   16907 C CB  . ASN D 1 354 ? 175.612 122.628 123.632 1.00 39.77  ? 354 ASN D CB  1 
ATOM   16908 C CG  . ASN D 1 354 ? 175.010 123.972 123.262 1.00 46.37  ? 354 ASN D CG  1 
ATOM   16909 O OD1 . ASN D 1 354 ? 174.181 124.511 123.969 1.00 45.96  ? 354 ASN D OD1 1 
ATOM   16910 N ND2 . ASN D 1 354 ? 175.431 124.577 122.180 1.00 43.65  ? 354 ASN D ND2 1 
ATOM   16911 N N   . SER D 1 355 ? 172.861 120.058 123.057 1.00 29.65  ? 355 SER D N   1 
ATOM   16912 C CA  . SER D 1 355 ? 171.906 119.550 122.072 1.00 21.78  ? 355 SER D CA  1 
ATOM   16913 C C   . SER D 1 355 ? 170.619 120.372 122.045 1.00 19.27  ? 355 SER D C   1 
ATOM   16914 O O   . SER D 1 355 ? 170.356 121.174 122.937 1.00 28.48  ? 355 SER D O   1 
ATOM   16915 C CB  . SER D 1 355 ? 171.615 118.075 122.331 1.00 20.95  ? 355 SER D CB  1 
ATOM   16916 O OG  . SER D 1 355 ? 170.655 117.889 123.345 1.00 27.57  ? 355 SER D OG  1 
ATOM   16917 N N   . VAL D 1 356 ? 169.770 120.156 121.043 1.00 21.92  ? 356 VAL D N   1 
ATOM   16918 C CA  . VAL D 1 356 ? 168.446 120.800 120.961 1.00 18.73  ? 356 VAL D CA  1 
ATOM   16919 C C   . VAL D 1 356 ? 167.593 120.560 122.206 1.00 15.30  ? 356 VAL D C   1 
ATOM   16920 O O   . VAL D 1 356 ? 166.909 121.475 122.650 1.00 30.37  ? 356 VAL D O   1 
ATOM   16921 C CB  . VAL D 1 356 ? 167.735 120.342 119.681 1.00 25.48  ? 356 VAL D CB  1 
ATOM   16922 C CG1 . VAL D 1 356 ? 166.223 120.501 119.656 1.00 25.95  ? 356 VAL D CG1 1 
ATOM   16923 C CG2 . VAL D 1 356 ? 168.319 121.077 118.476 1.00 19.97  ? 356 VAL D CG2 1 
ATOM   16924 N N   . LEU D 1 357 ? 167.648 119.372 122.810 1.00 35.64  ? 357 LEU D N   1 
ATOM   16925 C CA  . LEU D 1 357 ? 166.920 119.084 124.046 1.00 19.10  ? 357 LEU D CA  1 
ATOM   16926 C C   . LEU D 1 357 ? 167.422 119.910 125.232 1.00 17.29  ? 357 LEU D C   1 
ATOM   16927 O O   . LEU D 1 357 ? 166.620 120.509 125.939 1.00 25.97  ? 357 LEU D O   1 
ATOM   16928 C CB  . LEU D 1 357 ? 167.023 117.588 124.359 1.00 22.65  ? 357 LEU D CB  1 
ATOM   16929 C CG  . LEU D 1 357 ? 166.239 116.661 123.421 1.00 23.00  ? 357 LEU D CG  1 
ATOM   16930 C CD1 . LEU D 1 357 ? 166.500 115.221 123.844 1.00 22.52  ? 357 LEU D CD1 1 
ATOM   16931 C CD2 . LEU D 1 357 ? 164.737 116.915 123.485 1.00 25.16  ? 357 LEU D CD2 1 
ATOM   16932 N N   . GLU D 1 358 ? 168.738 119.996 125.435 1.00 25.47  ? 358 GLU D N   1 
ATOM   16933 C CA  . GLU D 1 358 ? 169.331 120.846 126.469 1.00 20.32  ? 358 GLU D CA  1 
ATOM   16934 C C   . GLU D 1 358 ? 169.022 122.333 126.241 1.00 29.36  ? 358 GLU D C   1 
ATOM   16935 O O   . GLU D 1 358 ? 168.701 123.052 127.186 1.00 36.00  ? 358 GLU D O   1 
ATOM   16936 C CB  . GLU D 1 358 ? 170.841 120.566 126.554 1.00 26.23  ? 358 GLU D CB  1 
ATOM   16937 C CG  . GLU D 1 358 ? 171.523 121.453 127.602 1.00 35.82  ? 358 GLU D CG  1 
ATOM   16938 C CD  . GLU D 1 358 ? 172.856 120.904 128.126 1.00 45.71  ? 358 GLU D CD  1 
ATOM   16939 O OE1 . GLU D 1 358 ? 173.734 120.546 127.309 1.00 46.33  ? 358 GLU D OE1 1 
ATOM   16940 O OE2 . GLU D 1 358 ? 173.026 120.863 129.367 1.00 41.00  ? 358 GLU D OE2 1 
ATOM   16941 N N   . ILE D 1 359 ? 169.035 122.794 124.991 1.00 25.01  ? 359 ILE D N   1 
ATOM   16942 C CA  . ILE D 1 359 ? 168.681 124.165 124.628 1.00 24.21  ? 359 ILE D CA  1 
ATOM   16943 C C   . ILE D 1 359 ? 167.211 124.469 124.911 1.00 23.34  ? 359 ILE D C   1 
ATOM   16944 O O   . ILE D 1 359 ? 166.930 125.479 125.544 1.00 35.36  ? 359 ILE D O   1 
ATOM   16945 C CB  . ILE D 1 359 ? 169.067 124.464 123.168 1.00 23.54  ? 359 ILE D CB  1 
ATOM   16946 C CG1 . ILE D 1 359 ? 170.601 124.535 123.052 1.00 18.08  ? 359 ILE D CG1 1 
ATOM   16947 C CG2 . ILE D 1 359 ? 168.445 125.772 122.662 1.00 22.39  ? 359 ILE D CG2 1 
ATOM   16948 C CD1 . ILE D 1 359 ? 171.100 124.404 121.625 1.00 22.31  ? 359 ILE D CD1 1 
ATOM   16949 N N   . ILE D 1 360 ? 166.250 123.638 124.499 1.00 26.23  ? 360 ILE D N   1 
ATOM   16950 C CA  . ILE D 1 360 ? 164.827 123.891 124.782 1.00 23.61  ? 360 ILE D CA  1 
ATOM   16951 C C   . ILE D 1 360 ? 164.555 123.907 126.290 1.00 26.51  ? 360 ILE D C   1 
ATOM   16952 O O   . ILE D 1 360 ? 163.850 124.786 126.784 1.00 34.65  ? 360 ILE D O   1 
ATOM   16953 C CB  . ILE D 1 360 ? 163.914 122.872 124.068 1.00 28.36  ? 360 ILE D CB  1 
ATOM   16954 C CG1 . ILE D 1 360 ? 163.995 123.035 122.542 1.00 21.88  ? 360 ILE D CG1 1 
ATOM   16955 C CG2 . ILE D 1 360 ? 162.449 123.038 124.512 1.00 21.69  ? 360 ILE D CG2 1 
ATOM   16956 C CD1 . ILE D 1 360 ? 163.480 121.818 121.772 1.00 22.19  ? 360 ILE D CD1 1 
ATOM   16957 N N   . ALA D 1 361 ? 165.130 122.965 127.037 1.00 27.43  ? 361 ALA D N   1 
ATOM   16958 C CA  . ALA D 1 361 ? 164.913 122.863 128.469 1.00 15.71  ? 361 ALA D CA  1 
ATOM   16959 C C   . ALA D 1 361 ? 165.517 124.043 129.252 1.00 23.10  ? 361 ALA D C   1 
ATOM   16960 O O   . ALA D 1 361 ? 164.821 124.612 130.089 1.00 29.44  ? 361 ALA D O   1 
ATOM   16961 C CB  . ALA D 1 361 ? 165.452 121.515 128.932 1.00 19.33  ? 361 ALA D CB  1 
ATOM   16962 N N   . PHE D 1 362 ? 166.767 124.433 128.978 1.00 26.02  ? 362 PHE D N   1 
ATOM   16963 C CA  . PHE D 1 362 ? 167.532 125.315 129.866 1.00 15.26  ? 362 PHE D CA  1 
ATOM   16964 C C   . PHE D 1 362 ? 168.038 126.627 129.263 1.00 25.99  ? 362 PHE D C   1 
ATOM   16965 O O   . PHE D 1 362 ? 168.336 127.539 130.030 1.00 39.19  ? 362 PHE D O   1 
ATOM   16966 C CB  . PHE D 1 362 ? 168.709 124.526 130.453 1.00 20.23  ? 362 PHE D CB  1 
ATOM   16967 C CG  . PHE D 1 362 ? 168.305 123.251 131.158 1.00 25.61  ? 362 PHE D CG  1 
ATOM   16968 C CD1 . PHE D 1 362 ? 167.599 123.305 132.371 1.00 24.75  ? 362 PHE D CD1 1 
ATOM   16969 C CD2 . PHE D 1 362 ? 168.583 122.006 130.572 1.00 29.32  ? 362 PHE D CD2 1 
ATOM   16970 C CE1 . PHE D 1 362 ? 167.176 122.120 132.991 1.00 25.99  ? 362 PHE D CE1 1 
ATOM   16971 C CE2 . PHE D 1 362 ? 168.160 120.821 131.191 1.00 23.42  ? 362 PHE D CE2 1 
ATOM   16972 C CZ  . PHE D 1 362 ? 167.449 120.878 132.398 1.00 27.02  ? 362 PHE D CZ  1 
ATOM   16973 N N   . HIS D 1 363 ? 168.186 126.760 127.941 1.00 26.53  ? 363 HIS D N   1 
ATOM   16974 C CA  . HIS D 1 363 ? 168.765 127.965 127.320 1.00 26.29  ? 363 HIS D CA  1 
ATOM   16975 C C   . HIS D 1 363 ? 167.718 128.830 126.618 1.00 30.54  ? 363 HIS D C   1 
ATOM   16976 O O   . HIS D 1 363 ? 167.892 130.034 126.483 1.00 38.18  ? 363 HIS D O   1 
ATOM   16977 C CB  . HIS D 1 363 ? 169.863 127.584 126.329 1.00 22.45  ? 363 HIS D CB  1 
ATOM   16978 C CG  . HIS D 1 363 ? 170.977 126.716 126.851 1.00 25.72  ? 363 HIS D CG  1 
ATOM   16979 N ND1 . HIS D 1 363 ? 171.945 126.129 126.040 1.00 40.84  ? 363 HIS D ND1 1 
ATOM   16980 C CD2 . HIS D 1 363 ? 171.257 126.398 128.145 1.00 30.29  ? 363 HIS D CD2 1 
ATOM   16981 C CE1 . HIS D 1 363 ? 172.759 125.448 126.857 1.00 36.77  ? 363 HIS D CE1 1 
ATOM   16982 N NE2 . HIS D 1 363 ? 172.367 125.594 128.126 1.00 36.73  ? 363 HIS D NE2 1 
ATOM   16983 N N   . CYS D 1 364 ? 166.631 128.228 126.162 1.00 29.79  ? 364 CYS D N   1 
ATOM   16984 C CA  . CYS D 1 364 ? 165.493 128.925 125.595 1.00 26.62  ? 364 CYS D CA  1 
ATOM   16985 C C   . CYS D 1 364 ? 164.696 129.638 126.703 1.00 34.81  ? 364 CYS D C   1 
ATOM   16986 O O   . CYS D 1 364 ? 164.501 129.086 127.783 1.00 32.33  ? 364 CYS D O   1 
ATOM   16987 C CB  . CYS D 1 364 ? 164.662 127.901 124.817 1.00 24.75  ? 364 CYS D CB  1 
ATOM   16988 S SG  . CYS D 1 364 ? 163.314 128.722 123.951 1.00 25.19  ? 364 CYS D SG  1 
ATOM   16989 N N   . LYS D 1 365 ? 164.192 130.842 126.422 1.00 41.48  ? 365 LYS D N   1 
ATOM   16990 C CA  . LYS D 1 365 ? 163.299 131.613 127.307 1.00 35.42  ? 365 LYS D CA  1 
ATOM   16991 C C   . LYS D 1 365 ? 161.992 132.060 126.651 1.00 34.83  ? 365 LYS D C   1 
ATOM   16992 O O   . LYS D 1 365 ? 161.294 132.929 127.163 1.00 44.31  ? 365 LYS D O   1 
ATOM   16993 C CB  . LYS D 1 365 ? 164.083 132.732 128.006 1.00 41.38  ? 365 LYS D CB  1 
ATOM   16994 C CG  . LYS D 1 365 ? 164.635 133.808 127.069 1.00 41.92  ? 365 LYS D CG  1 
ATOM   16995 C CD  . LYS D 1 365 ? 165.421 134.849 127.869 1.00 42.97  ? 365 LYS D CD  1 
ATOM   16996 C CE  . LYS D 1 365 ? 165.951 135.950 126.953 1.00 44.51  ? 365 LYS D CE  1 
ATOM   16997 N NZ  . LYS D 1 365 ? 166.680 136.985 127.719 1.00 43.68  ? 365 LYS D NZ  1 
ATOM   16998 N N   . SER D 1 366 ? 161.652 131.455 125.520 1.00 34.77  ? 366 SER D N   1 
ATOM   16999 C CA  . SER D 1 366 ? 160.394 131.670 124.804 1.00 33.52  ? 366 SER D CA  1 
ATOM   17000 C C   . SER D 1 366 ? 159.206 131.007 125.520 1.00 28.32  ? 366 SER D C   1 
ATOM   17001 O O   . SER D 1 366 ? 159.374 129.924 126.081 1.00 35.10  ? 366 SER D O   1 
ATOM   17002 C CB  . SER D 1 366 ? 160.551 131.109 123.390 1.00 32.52  ? 366 SER D CB  1 
ATOM   17003 O OG  . SER D 1 366 ? 159.388 131.308 122.626 1.00 33.45  ? 366 SER D OG  1 
ATOM   17004 N N   . PRO D 1 367 ? 157.981 131.560 125.474 1.00 37.32  ? 367 PRO D N   1 
ATOM   17005 C CA  . PRO D 1 367 ? 156.800 130.929 126.072 1.00 37.80  ? 367 PRO D CA  1 
ATOM   17006 C C   . PRO D 1 367 ? 156.346 129.634 125.379 1.00 40.74  ? 367 PRO D C   1 
ATOM   17007 O O   . PRO D 1 367 ? 155.542 128.891 125.932 1.00 48.45  ? 367 PRO D O   1 
ATOM   17008 C CB  . PRO D 1 367 ? 155.712 132.001 126.020 1.00 41.59  ? 367 PRO D CB  1 
ATOM   17009 C CG  . PRO D 1 367 ? 156.117 132.877 124.842 1.00 38.19  ? 367 PRO D CG  1 
ATOM   17010 C CD  . PRO D 1 367 ? 157.637 132.865 124.930 1.00 39.45  ? 367 PRO D CD  1 
ATOM   17011 N N   . ASN D 1 368 ? 156.829 129.359 124.164 1.00 34.15  ? 368 ASN D N   1 
ATOM   17012 C CA  . ASN D 1 368 ? 156.444 128.194 123.360 1.00 34.84  ? 368 ASN D CA  1 
ATOM   17013 C C   . ASN D 1 368 ? 157.389 126.984 123.487 1.00 36.18  ? 368 ASN D C   1 
ATOM   17014 O O   . ASN D 1 368 ? 157.279 126.041 122.704 1.00 44.69  ? 368 ASN D O   1 
ATOM   17015 C CB  . ASN D 1 368 ? 156.183 128.630 121.903 1.00 39.74  ? 368 ASN D CB  1 
ATOM   17016 C CG  . ASN D 1 368 ? 157.402 129.130 121.163 1.00 38.85  ? 368 ASN D CG  1 
ATOM   17017 O OD1 . ASN D 1 368 ? 158.534 129.017 121.605 1.00 46.06  ? 368 ASN D OD1 1 
ATOM   17018 N ND2 . ASN D 1 368 ? 157.219 129.745 120.028 1.00 33.67  ? 368 ASN D ND2 1 
ATOM   17019 N N   . ARG D 1 369 ? 158.272 126.941 124.494 1.00 27.25  ? 369 ARG D N   1 
ATOM   17020 C CA  . ARG D 1 369 ? 159.120 125.771 124.807 1.00 29.07  ? 369 ARG D CA  1 
ATOM   17021 C C   . ARG D 1 369 ? 158.325 124.479 124.931 1.00 28.00  ? 369 ARG D C   1 
ATOM   17022 O O   . ARG D 1 369 ? 158.743 123.436 124.441 1.00 29.83  ? 369 ARG D O   1 
ATOM   17023 C CB  . ARG D 1 369 ? 159.882 126.019 126.117 1.00 28.58  ? 369 ARG D CB  1 
ATOM   17024 C CG  . ARG D 1 369 ? 161.074 126.943 125.904 1.00 28.78  ? 369 ARG D CG  1 
ATOM   17025 C CD  . ARG D 1 369 ? 161.560 127.572 127.206 1.00 33.15  ? 369 ARG D CD  1 
ATOM   17026 N NE  . ARG D 1 369 ? 162.031 126.586 128.197 1.00 33.56  ? 369 ARG D NE  1 
ATOM   17027 C CZ  . ARG D 1 369 ? 161.516 126.357 129.390 1.00 29.11  ? 369 ARG D CZ  1 
ATOM   17028 N NH1 . ARG D 1 369 ? 162.085 125.578 130.251 1.00 21.79  ? 369 ARG D NH1 1 
ATOM   17029 N NH2 . ARG D 1 369 ? 160.398 126.891 129.774 1.00 31.11  ? 369 ARG D NH2 1 
ATOM   17030 N N   . HIS D 1 370 ? 157.145 124.539 125.543 1.00 31.40  ? 370 HIS D N   1 
ATOM   17031 C CA  . HIS D 1 370 ? 156.293 123.370 125.738 1.00 28.29  ? 370 HIS D CA  1 
ATOM   17032 C C   . HIS D 1 370 ? 155.664 122.852 124.438 1.00 28.19  ? 370 HIS D C   1 
ATOM   17033 O O   . HIS D 1 370 ? 155.348 121.647 124.393 1.00 36.87  ? 370 HIS D O   1 
ATOM   17034 C CB  . HIS D 1 370 ? 155.197 123.692 126.764 1.00 27.88  ? 370 HIS D CB  1 
ATOM   17035 C CG  . HIS D 1 370 ? 154.198 124.688 126.278 1.00 28.58  ? 370 HIS D CG  1 
ATOM   17036 N ND1 . HIS D 1 370 ? 152.971 124.312 125.769 1.00 27.18  ? 370 HIS D ND1 1 
ATOM   17037 C CD2 . HIS D 1 370 ? 154.239 126.036 126.214 1.00 32.07  ? 370 HIS D CD2 1 
ATOM   17038 C CE1 . HIS D 1 370 ? 152.296 125.387 125.416 1.00 33.53  ? 370 HIS D CE1 1 
ATOM   17039 N NE2 . HIS D 1 370 ? 153.053 126.460 125.679 1.00 36.00  ? 370 HIS D NE2 1 
ATOM   17040 N N   . ARG D 1 371 ? 155.491 123.706 123.423 1.00 31.10  ? 371 ARG D N   1 
ATOM   17041 C CA  . ARG D 1 371 ? 155.068 123.296 122.079 1.00 29.03  ? 371 ARG D CA  1 
ATOM   17042 C C   . ARG D 1 371 ? 156.196 122.625 121.287 1.00 31.75  ? 371 ARG D C   1 
ATOM   17043 O O   . ARG D 1 371 ? 155.921 121.721 120.512 1.00 28.95  ? 371 ARG D O   1 
ATOM   17044 C CB  . ARG D 1 371 ? 154.493 124.508 121.330 1.00 28.97  ? 371 ARG D CB  1 
ATOM   17045 C CG  . ARG D 1 371 ? 153.122 124.951 121.844 1.00 27.08  ? 371 ARG D CG  1 
ATOM   17046 C CD  . ARG D 1 371 ? 152.705 126.361 121.394 1.00 38.21  ? 371 ARG D CD  1 
ATOM   17047 N NE  . ARG D 1 371 ? 152.953 126.687 119.968 1.00 38.63  ? 371 ARG D NE  1 
ATOM   17048 C CZ  . ARG D 1 371 ? 152.364 126.190 118.895 1.00 38.70  ? 371 ARG D CZ  1 
ATOM   17049 N NH1 . ARG D 1 371 ? 152.607 126.688 117.723 1.00 36.80  ? 371 ARG D NH1 1 
ATOM   17050 N NH2 . ARG D 1 371 ? 151.524 125.203 118.952 1.00 37.65  ? 371 ARG D NH2 1 
ATOM   17051 N N   . MET D 1 372 ? 157.457 123.007 121.495 1.00 30.92  ? 372 MET D N   1 
ATOM   17052 C CA  . MET D 1 372 ? 158.607 122.378 120.834 1.00 20.81  ? 372 MET D CA  1 
ATOM   17053 C C   . MET D 1 372 ? 158.911 120.954 121.315 1.00 29.09  ? 372 MET D C   1 
ATOM   17054 O O   . MET D 1 372 ? 159.261 120.109 120.498 1.00 40.22  ? 372 MET D O   1 
ATOM   17055 C CB  . MET D 1 372 ? 159.861 123.245 120.968 1.00 20.21  ? 372 MET D CB  1 
ATOM   17056 C CG  . MET D 1 372 ? 159.756 124.522 120.139 1.00 34.13  ? 372 MET D CG  1 
ATOM   17057 S SD  . MET D 1 372 ? 161.288 125.464 119.985 1.00 47.10  ? 372 MET D SD  1 
ATOM   17058 C CE  . MET D 1 372 ? 161.412 126.132 121.660 1.00 27.45  ? 372 MET D CE  1 
ATOM   17059 N N   . VAL D 1 373 ? 158.766 120.640 122.607 1.00 27.91  ? 373 VAL D N   1 
ATOM   17060 C CA  . VAL D 1 373 ? 159.081 119.294 123.136 1.00 24.47  ? 373 VAL D CA  1 
ATOM   17061 C C   . VAL D 1 373 ? 158.082 118.210 122.720 1.00 27.27  ? 373 VAL D C   1 
ATOM   17062 O O   . VAL D 1 373 ? 158.384 117.030 122.850 1.00 33.42  ? 373 VAL D O   1 
ATOM   17063 C CB  . VAL D 1 373 ? 159.258 119.264 124.668 1.00 31.43  ? 373 VAL D CB  1 
ATOM   17064 C CG1 . VAL D 1 373 ? 160.401 120.159 125.121 1.00 27.63  ? 373 VAL D CG1 1 
ATOM   17065 C CG2 . VAL D 1 373 ? 157.994 119.634 125.433 1.00 19.54  ? 373 VAL D CG2 1 
ATOM   17066 N N   . VAL D 1 374 ? 156.906 118.587 122.215 1.00 21.51  ? 374 VAL D N   1 
ATOM   17067 C CA  . VAL D 1 374 ? 155.855 117.654 121.778 1.00 18.12  ? 374 VAL D CA  1 
ATOM   17068 C C   . VAL D 1 374 ? 155.828 117.424 120.260 1.00 23.25  ? 374 VAL D C   1 
ATOM   17069 O O   . VAL D 1 374 ? 154.930 116.756 119.758 1.00 31.19  ? 374 VAL D O   1 
ATOM   17070 C CB  . VAL D 1 374 ? 154.473 118.022 122.360 1.00 23.21  ? 374 VAL D CB  1 
ATOM   17071 C CG1 . VAL D 1 374 ? 154.498 118.036 123.889 1.00 29.00  ? 374 VAL D CG1 1 
ATOM   17072 C CG2 . VAL D 1 374 ? 153.947 119.366 121.872 1.00 23.29  ? 374 VAL D CG2 1 
ATOM   17073 N N   . LEU D 1 375 ? 156.811 117.938 119.515 1.00 25.16  ? 375 LEU D N   1 
ATOM   17074 C CA  . LEU D 1 375 ? 157.007 117.646 118.090 1.00 26.60  ? 375 LEU D CA  1 
ATOM   17075 C C   . LEU D 1 375 ? 157.680 116.280 117.888 1.00 27.96  ? 375 LEU D C   1 
ATOM   17076 O O   . LEU D 1 375 ? 158.495 115.877 118.706 1.00 30.74  ? 375 LEU D O   1 
ATOM   17077 C CB  . LEU D 1 375 ? 157.867 118.758 117.464 1.00 28.46  ? 375 LEU D CB  1 
ATOM   17078 C CG  . LEU D 1 375 ? 157.303 120.178 117.596 1.00 23.47  ? 375 LEU D CG  1 
ATOM   17079 C CD1 . LEU D 1 375 ? 158.257 121.166 116.952 1.00 23.02  ? 375 LEU D CD1 1 
ATOM   17080 C CD2 . LEU D 1 375 ? 155.938 120.326 116.941 1.00 26.31  ? 375 LEU D CD2 1 
ATOM   17081 N N   . GLU D 1 376 ? 157.435 115.573 116.784 1.00 31.53  ? 376 GLU D N   1 
ATOM   17082 C CA  . GLU D 1 376 ? 158.320 114.469 116.372 1.00 32.11  ? 376 GLU D CA  1 
ATOM   17083 C C   . GLU D 1 376 ? 159.680 115.006 115.889 1.00 26.50  ? 376 GLU D C   1 
ATOM   17084 O O   . GLU D 1 376 ? 159.704 116.045 115.226 1.00 34.91  ? 376 GLU D O   1 
ATOM   17085 C CB  . GLU D 1 376 ? 157.692 113.618 115.261 1.00 32.34  ? 376 GLU D CB  1 
ATOM   17086 C CG  . GLU D 1 376 ? 156.474 112.813 115.718 1.00 34.25  ? 376 GLU D CG  1 
ATOM   17087 C CD  . GLU D 1 376 ? 155.796 112.019 114.575 1.00 46.17  ? 376 GLU D CD  1 
ATOM   17088 O OE1 . GLU D 1 376 ? 156.410 111.824 113.499 1.00 44.27  ? 376 GLU D OE1 1 
ATOM   17089 O OE2 . GLU D 1 376 ? 154.638 111.592 114.773 1.00 46.32  ? 376 GLU D OE2 1 
ATOM   17090 N N   . PRO D 1 377 ? 160.809 114.318 116.156 1.00 22.39  ? 377 PRO D N   1 
ATOM   17091 C CA  . PRO D 1 377 ? 160.937 113.082 116.931 1.00 21.06  ? 377 PRO D CA  1 
ATOM   17092 C C   . PRO D 1 377 ? 161.123 113.332 118.442 1.00 24.64  ? 377 PRO D C   1 
ATOM   17093 O O   . PRO D 1 377 ? 161.329 112.359 119.144 1.00 28.92  ? 377 PRO D O   1 
ATOM   17094 C CB  . PRO D 1 377 ? 162.249 112.471 116.442 1.00 21.74  ? 377 PRO D CB  1 
ATOM   17095 C CG  . PRO D 1 377 ? 163.112 113.697 116.173 1.00 27.01  ? 377 PRO D CG  1 
ATOM   17096 C CD  . PRO D 1 377 ? 162.106 114.700 115.620 1.00 15.73  ? 377 PRO D CD  1 
ATOM   17097 N N   . LEU D 1 378 ? 161.042 114.586 118.915 1.00 30.89  ? 378 LEU D N   1 
ATOM   17098 C CA  . LEU D 1 378 ? 161.322 114.927 120.350 1.00 23.66  ? 378 LEU D CA  1 
ATOM   17099 C C   . LEU D 1 378 ? 160.301 114.285 121.300 1.00 28.91  ? 378 LEU D C   1 
ATOM   17100 O O   . LEU D 1 378 ? 160.698 113.782 122.342 1.00 35.48  ? 378 LEU D O   1 
ATOM   17101 C CB  . LEU D 1 378 ? 161.313 116.452 120.506 1.00 26.44  ? 378 LEU D CB  1 
ATOM   17102 C CG  . LEU D 1 378 ? 162.603 117.169 120.110 1.00 29.37  ? 378 LEU D CG  1 
ATOM   17103 C CD1 . LEU D 1 378 ? 162.942 116.923 118.648 1.00 26.46  ? 378 LEU D CD1 1 
ATOM   17104 C CD2 . LEU D 1 378 ? 162.496 118.662 120.385 1.00 29.92  ? 378 LEU D CD2 1 
ATOM   17105 N N   . ASN D 1 379 ? 159.023 114.232 120.940 1.00 27.56  ? 379 ASN D N   1 
ATOM   17106 C CA  . ASN D 1 379 ? 157.966 113.625 121.736 1.00 13.97  ? 379 ASN D CA  1 
ATOM   17107 C C   . ASN D 1 379 ? 158.251 112.152 122.080 1.00 19.97  ? 379 ASN D C   1 
ATOM   17108 O O   . ASN D 1 379 ? 158.322 111.792 123.250 1.00 36.01  ? 379 ASN D O   1 
ATOM   17109 C CB  . ASN D 1 379 ? 156.649 113.793 120.970 1.00 20.00  ? 379 ASN D CB  1 
ATOM   17110 C CG  . ASN D 1 379 ? 155.439 113.376 121.783 1.00 33.20  ? 379 ASN D CG  1 
ATOM   17111 O OD1 . ASN D 1 379 ? 155.207 113.846 122.881 1.00 36.70  ? 379 ASN D OD1 1 
ATOM   17112 N ND2 . ASN D 1 379 ? 154.634 112.481 121.279 1.00 30.42  ? 379 ASN D ND2 1 
ATOM   17113 N N   . LYS D 1 380 ? 158.452 111.291 121.074 1.00 32.46  ? 380 LYS D N   1 
ATOM   17114 C CA  . LYS D 1 380 ? 158.732 109.865 121.286 1.00 24.60  ? 380 LYS D CA  1 
ATOM   17115 C C   . LYS D 1 380 ? 160.125 109.651 121.875 1.00 22.87  ? 380 LYS D C   1 
ATOM   17116 O O   . LYS D 1 380 ? 160.298 108.770 122.707 1.00 33.77  ? 380 LYS D O   1 
ATOM   17117 C CB  . LYS D 1 380 ? 158.494 109.062 119.989 1.00 27.43  ? 380 LYS D CB  1 
ATOM   17118 C CG  . LYS D 1 380 ? 158.644 107.547 120.247 1.00 36.01  ? 380 LYS D CG  1 
ATOM   17119 C CD  . LYS D 1 380 ? 158.736 106.665 119.001 1.00 32.56  ? 380 LYS D CD  1 
ATOM   17120 C CE  . LYS D 1 380 ? 159.098 105.243 119.459 1.00 35.04  ? 380 LYS D CE  1 
ATOM   17121 N NZ  . LYS D 1 380 ? 159.307 104.311 118.325 1.00 34.60  ? 380 LYS D NZ  1 
ATOM   17122 N N   . LEU D 1 381 ? 161.105 110.469 121.508 1.00 16.57  ? 381 LEU D N   1 
ATOM   17123 C CA  . LEU D 1 381 ? 162.452 110.409 122.071 1.00 19.42  ? 381 LEU D CA  1 
ATOM   17124 C C   . LEU D 1 381 ? 162.458 110.713 123.575 1.00 23.99  ? 381 LEU D C   1 
ATOM   17125 O O   . LEU D 1 381 ? 163.060 109.994 124.362 1.00 35.47  ? 381 LEU D O   1 
ATOM   17126 C CB  . LEU D 1 381 ? 163.332 111.384 121.273 1.00 25.64  ? 381 LEU D CB  1 
ATOM   17127 C CG  . LEU D 1 381 ? 164.796 111.441 121.718 1.00 30.04  ? 381 LEU D CG  1 
ATOM   17128 C CD1 . LEU D 1 381 ? 165.505 110.125 121.452 1.00 28.72  ? 381 LEU D CD1 1 
ATOM   17129 C CD2 . LEU D 1 381 ? 165.506 112.548 120.950 1.00 27.08  ? 381 LEU D CD2 1 
ATOM   17130 N N   . LEU D 1 382 ? 161.744 111.749 124.006 1.00 30.48  ? 382 LEU D N   1 
ATOM   17131 C CA  . LEU D 1 382 ? 161.579 112.082 125.417 1.00 18.83  ? 382 LEU D CA  1 
ATOM   17132 C C   . LEU D 1 382 ? 160.742 111.048 126.161 1.00 20.21  ? 382 LEU D C   1 
ATOM   17133 O O   . LEU D 1 382 ? 161.058 110.754 127.307 1.00 35.02  ? 382 LEU D O   1 
ATOM   17134 C CB  . LEU D 1 382 ? 160.985 113.488 125.552 1.00 20.59  ? 382 LEU D CB  1 
ATOM   17135 C CG  . LEU D 1 382 ? 161.999 114.603 125.254 1.00 19.70  ? 382 LEU D CG  1 
ATOM   17136 C CD1 . LEU D 1 382 ? 161.262 115.922 125.092 1.00 16.69  ? 382 LEU D CD1 1 
ATOM   17137 C CD2 . LEU D 1 382 ? 163.030 114.742 126.374 1.00 22.15  ? 382 LEU D CD2 1 
ATOM   17138 N N   . GLN D 1 383 ? 159.788 110.413 125.477 1.00 23.11  ? 383 GLN D N   1 
ATOM   17139 C CA  . GLN D 1 383 ? 159.025 109.315 126.132 1.00 16.96  ? 383 GLN D CA  1 
ATOM   17140 C C   . GLN D 1 383 ? 159.972 108.119 126.338 1.00 18.80  ? 383 GLN D C   1 
ATOM   17141 O O   . GLN D 1 383 ? 159.967 107.568 127.457 1.00 36.27  ? 383 GLN D O   1 
ATOM   17142 C CB  . GLN D 1 383 ? 157.748 109.016 125.336 1.00 20.50  ? 383 GLN D CB  1 
ATOM   17143 C CG  . GLN D 1 383 ? 156.795 108.061 126.067 1.00 27.15  ? 383 GLN D CG  1 
ATOM   17144 C CD  . GLN D 1 383 ? 156.394 108.583 127.424 1.00 34.10  ? 383 GLN D CD  1 
ATOM   17145 O OE1 . GLN D 1 383 ? 156.418 109.784 127.683 1.00 37.34  ? 383 GLN D OE1 1 
ATOM   17146 N NE2 . GLN D 1 383 ? 156.011 107.675 128.307 1.00 27.25  ? 383 GLN D NE2 1 
ATOM   17147 N N   . GLU D 1 384 ? 160.758 107.732 125.322 1.00 29.60  ? 384 GLU D N   1 
ATOM   17148 C CA  . GLU D 1 384 ? 161.757 106.673 125.467 1.00 29.50  ? 384 GLU D CA  1 
ATOM   17149 C C   . GLU D 1 384 ? 162.746 106.937 126.607 1.00 28.08  ? 384 GLU D C   1 
ATOM   17150 O O   . GLU D 1 384 ? 163.085 106.017 127.350 1.00 34.91  ? 384 GLU D O   1 
ATOM   17151 C CB  . GLU D 1 384 ? 162.526 106.516 124.144 1.00 32.49  ? 384 GLU D CB  1 
ATOM   17152 C CG  . GLU D 1 384 ? 161.780 105.645 123.125 1.00 33.51  ? 384 GLU D CG  1 
ATOM   17153 C CD  . GLU D 1 384 ? 161.898 104.141 123.395 1.00 44.15  ? 384 GLU D CD  1 
ATOM   17154 O OE1 . GLU D 1 384 ? 162.562 103.730 124.375 1.00 46.48  ? 384 GLU D OE1 1 
ATOM   17155 O OE2 . GLU D 1 384 ? 161.337 103.357 122.599 1.00 43.34  ? 384 GLU D OE2 1 
ATOM   17156 N N   . LYS D 1 385 ? 163.199 108.183 126.780 1.00 30.69  ? 385 LYS D N   1 
ATOM   17157 C CA  . LYS D 1 385 ? 164.044 108.583 127.907 1.00 22.34  ? 385 LYS D CA  1 
ATOM   17158 C C   . LYS D 1 385 ? 163.293 108.525 129.235 1.00 24.81  ? 385 LYS D C   1 
ATOM   17159 O O   . LYS D 1 385 ? 163.840 108.027 130.211 1.00 26.52  ? 385 LYS D O   1 
ATOM   17160 C CB  . LYS D 1 385 ? 164.607 109.984 127.668 1.00 24.31  ? 385 LYS D CB  1 
ATOM   17161 C CG  . LYS D 1 385 ? 165.664 110.037 126.565 1.00 22.06  ? 385 LYS D CG  1 
ATOM   17162 C CD  . LYS D 1 385 ? 166.083 111.474 126.247 1.00 23.09  ? 385 LYS D CD  1 
ATOM   17163 C CE  . LYS D 1 385 ? 167.078 111.545 125.089 1.00 25.88  ? 385 LYS D CE  1 
ATOM   17164 N NZ  . LYS D 1 385 ? 168.353 110.881 125.398 1.00 28.25  ? 385 LYS D NZ  1 
ATOM   17165 N N   . TRP D 1 386 ? 162.045 108.986 129.290 1.00 20.72  ? 386 TRP D N   1 
ATOM   17166 C CA  . TRP D 1 386 ? 161.212 108.886 130.490 1.00 13.26  ? 386 TRP D CA  1 
ATOM   17167 C C   . TRP D 1 386 ? 160.974 107.434 130.905 1.00 25.03  ? 386 TRP D C   1 
ATOM   17168 O O   . TRP D 1 386 ? 161.195 107.088 132.059 1.00 38.22  ? 386 TRP D O   1 
ATOM   17169 C CB  . TRP D 1 386 ? 159.873 109.609 130.306 1.00 23.45  ? 386 TRP D CB  1 
ATOM   17170 C CG  . TRP D 1 386 ? 158.994 109.519 131.520 1.00 22.59  ? 386 TRP D CG  1 
ATOM   17171 C CD1 . TRP D 1 386 ? 158.071 108.561 131.745 1.00 26.97  ? 386 TRP D CD1 1 
ATOM   17172 C CD2 . TRP D 1 386 ? 159.078 110.274 132.766 1.00 28.25  ? 386 TRP D CD2 1 
ATOM   17173 N NE1 . TRP D 1 386 ? 157.620 108.643 133.044 1.00 31.92  ? 386 TRP D NE1 1 
ATOM   17174 C CE2 . TRP D 1 386 ? 158.225 109.673 133.728 1.00 27.81  ? 386 TRP D CE2 1 
ATOM   17175 C CE3 . TRP D 1 386 ? 159.818 111.395 133.189 1.00 26.85  ? 386 TRP D CE3 1 
ATOM   17176 C CZ2 . TRP D 1 386 ? 158.120 110.148 135.044 1.00 23.15  ? 386 TRP D CZ2 1 
ATOM   17177 C CZ3 . TRP D 1 386 ? 159.739 111.875 134.506 1.00 19.05  ? 386 TRP D CZ3 1 
ATOM   17178 C CH2 . TRP D 1 386 ? 158.886 111.257 135.433 1.00 26.45  ? 386 TRP D CH2 1 
ATOM   17179 N N   . ASP D 1 387 ? 160.581 106.558 129.989 1.00 29.94  ? 387 ASP D N   1 
ATOM   17180 C CA  . ASP D 1 387 ? 160.271 105.162 130.293 1.00 26.01  ? 387 ASP D CA  1 
ATOM   17181 C C   . ASP D 1 387 ? 161.464 104.386 130.877 1.00 28.46  ? 387 ASP D C   1 
ATOM   17182 O O   . ASP D 1 387 ? 161.267 103.512 131.711 1.00 38.32  ? 387 ASP D O   1 
ATOM   17183 C CB  . ASP D 1 387 ? 159.743 104.455 129.038 1.00 28.09  ? 387 ASP D CB  1 
ATOM   17184 C CG  . ASP D 1 387 ? 158.365 104.926 128.553 1.00 35.08  ? 387 ASP D CG  1 
ATOM   17185 O OD1 . ASP D 1 387 ? 157.662 105.663 129.277 1.00 37.03  ? 387 ASP D OD1 1 
ATOM   17186 O OD2 . ASP D 1 387 ? 157.937 104.485 127.463 1.00 40.49  ? 387 ASP D OD2 1 
ATOM   17187 N N   . ARG D 1 388 ? 162.703 104.726 130.514 1.00 36.49  ? 388 ARG D N   1 
ATOM   17188 C CA  . ARG D 1 388 ? 163.916 104.139 131.111 1.00 35.98  ? 388 ARG D CA  1 
ATOM   17189 C C   . ARG D 1 388 ? 164.440 104.859 132.360 1.00 38.06  ? 388 ARG D C   1 
ATOM   17190 O O   . ARG D 1 388 ? 165.401 104.393 132.963 1.00 49.12  ? 388 ARG D O   1 
ATOM   17191 C CB  . ARG D 1 388 ? 164.985 103.907 130.034 1.00 34.95  ? 388 ARG D CB  1 
ATOM   17192 C CG  . ARG D 1 388 ? 165.643 105.183 129.505 1.00 39.96  ? 388 ARG D CG  1 
ATOM   17193 C CD  . ARG D 1 388 ? 166.511 104.916 128.271 1.00 42.49  ? 388 ARG D CD  1 
ATOM   17194 N NE  . ARG D 1 388 ? 165.702 104.494 127.108 1.00 48.12  ? 388 ARG D NE  1 
ATOM   17195 C CZ  . ARG D 1 388 ? 165.993 103.556 126.227 1.00 52.15  ? 388 ARG D CZ  1 
ATOM   17196 N NH1 . ARG D 1 388 ? 165.176 103.253 125.264 1.00 45.50  ? 388 ARG D NH1 1 
ATOM   17197 N NH2 . ARG D 1 388 ? 167.103 102.882 126.275 1.00 49.05  ? 388 ARG D NH2 1 
ATOM   17198 N N   . LEU D 1 389 ? 163.820 105.967 132.769 1.00 29.75  ? 389 LEU D N   1 
ATOM   17199 C CA  . LEU D 1 389 ? 164.183 106.757 133.954 1.00 22.38  ? 389 LEU D CA  1 
ATOM   17200 C C   . LEU D 1 389 ? 163.074 106.857 135.004 1.00 27.58  ? 389 LEU D C   1 
ATOM   17201 O O   . LEU D 1 389 ? 163.347 107.267 136.125 1.00 35.04  ? 389 LEU D O   1 
ATOM   17202 C CB  . LEU D 1 389 ? 164.621 108.162 133.525 1.00 28.34  ? 389 LEU D CB  1 
ATOM   17203 C CG  . LEU D 1 389 ? 165.995 108.212 132.851 1.00 27.26  ? 389 LEU D CG  1 
ATOM   17204 C CD1 . LEU D 1 389 ? 166.225 109.592 132.255 1.00 27.99  ? 389 LEU D CD1 1 
ATOM   17205 C CD2 . LEU D 1 389 ? 167.111 107.932 133.852 1.00 26.30  ? 389 LEU D CD2 1 
ATOM   17206 N N   . VAL D 1 390 ? 161.842 106.460 134.702 1.00 24.53  ? 390 VAL D N   1 
ATOM   17207 C CA  . VAL D 1 390 ? 160.703 106.553 135.626 1.00 26.50  ? 390 VAL D CA  1 
ATOM   17208 C C   . VAL D 1 390 ? 160.929 105.802 136.942 1.00 28.24  ? 390 VAL D C   1 
ATOM   17209 O O   . VAL D 1 390 ? 160.528 106.269 138.001 1.00 37.10  ? 390 VAL D O   1 
ATOM   17210 C CB  . VAL D 1 390 ? 159.417 106.111 134.909 1.00 28.26  ? 390 VAL D CB  1 
ATOM   17211 C CG1 . VAL D 1 390 ? 159.387 104.627 134.544 1.00 27.47  ? 390 VAL D CG1 1 
ATOM   17212 C CG2 . VAL D 1 390 ? 158.177 106.413 135.745 1.00 30.02  ? 390 VAL D CG2 1 
ATOM   17213 N N   . SER D 1 391 ? 161.650 104.682 136.919 1.00 31.34  ? 391 SER D N   1 
ATOM   17214 C CA  . SER D 1 391 ? 162.033 103.941 138.125 1.00 23.98  ? 391 SER D CA  1 
ATOM   17215 C C   . SER D 1 391 ? 163.019 104.725 139.004 1.00 26.49  ? 391 SER D C   1 
ATOM   17216 O O   . SER D 1 391 ? 162.887 104.714 140.225 1.00 34.89  ? 391 SER D O   1 
ATOM   17217 C CB  . SER D 1 391 ? 162.618 102.587 137.732 1.00 24.82  ? 391 SER D CB  1 
ATOM   17218 O OG  . SER D 1 391 ? 163.734 102.745 136.877 1.00 35.23  ? 391 SER D OG  1 
ATOM   17219 N N   . ARG D 1 392 ? 163.965 105.460 138.406 1.00 28.35  ? 392 ARG D N   1 
ATOM   17220 C CA  . ARG D 1 392 ? 164.874 106.382 139.100 1.00 20.04  ? 392 ARG D CA  1 
ATOM   17221 C C   . ARG D 1 392 ? 164.143 107.598 139.655 1.00 20.35  ? 392 ARG D C   1 
ATOM   17222 O O   . ARG D 1 392 ? 164.417 108.001 140.775 1.00 35.11  ? 392 ARG D O   1 
ATOM   17223 C CB  . ARG D 1 392 ? 166.018 106.776 138.161 1.00 27.91  ? 392 ARG D CB  1 
ATOM   17224 C CG  . ARG D 1 392 ? 167.044 107.689 138.844 1.00 22.94  ? 392 ARG D CG  1 
ATOM   17225 C CD  . ARG D 1 392 ? 168.296 107.891 137.994 1.00 33.01  ? 392 ARG D CD  1 
ATOM   17226 N NE  . ARG D 1 392 ? 169.090 106.646 137.892 1.00 45.97  ? 392 ARG D NE  1 
ATOM   17227 C CZ  . ARG D 1 392 ? 170.360 106.464 138.205 1.00 42.44  ? 392 ARG D CZ  1 
ATOM   17228 N NH1 . ARG D 1 392 ? 170.884 105.279 138.150 1.00 39.39  ? 392 ARG D NH1 1 
ATOM   17229 N NH2 . ARG D 1 392 ? 171.139 107.435 138.572 1.00 37.13  ? 392 ARG D NH2 1 
ATOM   17230 N N   . PHE D 1 393 ? 163.161 108.137 138.943 1.00 24.34  ? 393 PHE D N   1 
ATOM   17231 C CA  . PHE D 1 393 ? 162.315 109.221 139.439 1.00 10.16  ? 393 PHE D CA  1 
ATOM   17232 C C   . PHE D 1 393 ? 161.581 108.842 140.734 1.00 17.33  ? 393 PHE D C   1 
ATOM   17233 O O   . PHE D 1 393 ? 161.622 109.569 141.722 1.00 29.00  ? 393 PHE D O   1 
ATOM   17234 C CB  . PHE D 1 393 ? 161.317 109.634 138.354 1.00 14.00  ? 393 PHE D CB  1 
ATOM   17235 C CG  . PHE D 1 393 ? 160.536 110.880 138.696 1.00 17.89  ? 393 PHE D CG  1 
ATOM   17236 C CD1 . PHE D 1 393 ? 161.117 112.145 138.490 1.00 10.85  ? 393 PHE D CD1 1 
ATOM   17237 C CD2 . PHE D 1 393 ? 159.256 110.787 139.266 1.00 16.94  ? 393 PHE D CD2 1 
ATOM   17238 C CE1 . PHE D 1 393 ? 160.414 113.307 138.835 1.00 9.51   ? 393 PHE D CE1 1 
ATOM   17239 C CE2 . PHE D 1 393 ? 158.562 111.953 139.629 1.00 17.30  ? 393 PHE D CE2 1 
ATOM   17240 C CZ  . PHE D 1 393 ? 159.139 113.210 139.405 1.00 12.15  ? 393 PHE D CZ  1 
ATOM   17241 N N   . PHE D 1 394 ? 160.948 107.671 140.762 1.00 26.46  ? 394 PHE D N   1 
ATOM   17242 C CA  . PHE D 1 394 ? 160.236 107.200 141.944 1.00 15.58  ? 394 PHE D CA  1 
ATOM   17243 C C   . PHE D 1 394 ? 161.152 106.635 143.040 1.00 15.63  ? 394 PHE D C   1 
ATOM   17244 O O   . PHE D 1 394 ? 160.799 106.731 144.209 1.00 24.16  ? 394 PHE D O   1 
ATOM   17245 C CB  . PHE D 1 394 ? 159.097 106.274 141.530 1.00 17.93  ? 394 PHE D CB  1 
ATOM   17246 C CG  . PHE D 1 394 ? 157.968 107.033 140.860 1.00 19.60  ? 394 PHE D CG  1 
ATOM   17247 C CD1 . PHE D 1 394 ? 157.230 107.976 141.598 1.00 23.67  ? 394 PHE D CD1 1 
ATOM   17248 C CD2 . PHE D 1 394 ? 157.661 106.826 139.506 1.00 22.61  ? 394 PHE D CD2 1 
ATOM   17249 C CE1 . PHE D 1 394 ? 156.200 108.709 140.987 1.00 26.07  ? 394 PHE D CE1 1 
ATOM   17250 C CE2 . PHE D 1 394 ? 156.620 107.547 138.898 1.00 18.06  ? 394 PHE D CE2 1 
ATOM   17251 C CZ  . PHE D 1 394 ? 155.892 108.485 139.639 1.00 20.79  ? 394 PHE D CZ  1 
ATOM   17252 N N   . PHE D 1 395 ? 162.369 106.186 142.733 1.00 21.41  ? 395 PHE D N   1 
ATOM   17253 C CA  . PHE D 1 395 ? 163.413 105.993 143.736 1.00 16.85  ? 395 PHE D CA  1 
ATOM   17254 C C   . PHE D 1 395 ? 163.845 107.313 144.397 1.00 21.55  ? 395 PHE D C   1 
ATOM   17255 O O   . PHE D 1 395 ? 163.954 107.384 145.619 1.00 29.03  ? 395 PHE D O   1 
ATOM   17256 C CB  . PHE D 1 395 ? 164.608 105.281 143.103 1.00 19.00  ? 395 PHE D CB  1 
ATOM   17257 C CG  . PHE D 1 395 ? 165.791 105.146 144.033 1.00 25.43  ? 395 PHE D CG  1 
ATOM   17258 C CD1 . PHE D 1 395 ? 165.771 104.180 145.053 1.00 20.72  ? 395 PHE D CD1 1 
ATOM   17259 C CD2 . PHE D 1 395 ? 166.898 106.006 143.909 1.00 23.55  ? 395 PHE D CD2 1 
ATOM   17260 C CE1 . PHE D 1 395 ? 166.851 104.073 145.941 1.00 25.07  ? 395 PHE D CE1 1 
ATOM   17261 C CE2 . PHE D 1 395 ? 167.979 105.892 144.790 1.00 24.62  ? 395 PHE D CE2 1 
ATOM   17262 C CZ  . PHE D 1 395 ? 167.958 104.925 145.809 1.00 26.14  ? 395 PHE D CZ  1 
ATOM   17263 N N   . ASN D 1 396 ? 164.045 108.385 143.630 1.00 30.67  ? 396 ASN D N   1 
ATOM   17264 C CA  . ASN D 1 396 ? 164.354 109.711 144.168 1.00 18.26  ? 396 ASN D CA  1 
ATOM   17265 C C   . ASN D 1 396 ? 163.216 110.250 145.055 1.00 17.73  ? 396 ASN D C   1 
ATOM   17266 O O   . ASN D 1 396 ? 163.476 110.770 146.136 1.00 28.15  ? 396 ASN D O   1 
ATOM   17267 C CB  . ASN D 1 396 ? 164.644 110.679 143.012 1.00 17.22  ? 396 ASN D CB  1 
ATOM   17268 C CG  . ASN D 1 396 ? 165.920 110.400 142.247 1.00 20.73  ? 396 ASN D CG  1 
ATOM   17269 O OD1 . ASN D 1 396 ? 166.785 109.648 142.659 1.00 28.69  ? 396 ASN D OD1 1 
ATOM   17270 N ND2 . ASN D 1 396 ? 166.096 111.036 141.113 1.00 26.65  ? 396 ASN D ND2 1 
ATOM   17271 N N   . PHE D 1 397 ? 161.959 110.073 144.643 1.00 19.54  ? 397 PHE D N   1 
ATOM   17272 C CA  . PHE D 1 397 ? 160.776 110.377 145.447 1.00 8.69   ? 397 PHE D CA  1 
ATOM   17273 C C   . PHE D 1 397 ? 160.728 109.573 146.747 1.00 27.68  ? 397 PHE D C   1 
ATOM   17274 O O   . PHE D 1 397 ? 160.508 110.147 147.808 1.00 36.59  ? 397 PHE D O   1 
ATOM   17275 C CB  . PHE D 1 397 ? 159.519 110.092 144.626 1.00 13.60  ? 397 PHE D CB  1 
ATOM   17276 C CG  . PHE D 1 397 ? 158.222 110.152 145.399 1.00 23.85  ? 397 PHE D CG  1 
ATOM   17277 C CD1 . PHE D 1 397 ? 157.833 111.334 146.051 1.00 23.01  ? 397 PHE D CD1 1 
ATOM   17278 C CD2 . PHE D 1 397 ? 157.400 109.015 145.489 1.00 26.90  ? 397 PHE D CD2 1 
ATOM   17279 C CE1 . PHE D 1 397 ? 156.603 111.407 146.719 1.00 16.03  ? 397 PHE D CE1 1 
ATOM   17280 C CE2 . PHE D 1 397 ? 156.188 109.074 146.195 1.00 28.46  ? 397 PHE D CE2 1 
ATOM   17281 C CZ  . PHE D 1 397 ? 155.781 110.275 146.793 1.00 27.22  ? 397 PHE D CZ  1 
ATOM   17282 N N   . ALA D 1 398 ? 160.958 108.258 146.699 1.00 30.91  ? 398 ALA D N   1 
ATOM   17283 C CA  . ALA D 1 398 ? 160.979 107.407 147.880 1.00 11.33  ? 398 ALA D CA  1 
ATOM   17284 C C   . ALA D 1 398 ? 162.077 107.809 148.875 1.00 19.45  ? 398 ALA D C   1 
ATOM   17285 O O   . ALA D 1 398 ? 161.834 107.837 150.076 1.00 32.40  ? 398 ALA D O   1 
ATOM   17286 C CB  . ALA D 1 398 ? 161.140 105.958 147.423 1.00 23.88  ? 398 ALA D CB  1 
ATOM   17287 N N   . CYS D 1 399 ? 163.264 108.191 148.403 1.00 26.04  ? 399 CYS D N   1 
ATOM   17288 C CA  . CYS D 1 399 ? 164.328 108.707 149.261 1.00 23.70  ? 399 CYS D CA  1 
ATOM   17289 C C   . CYS D 1 399 ? 163.953 110.043 149.909 1.00 22.52  ? 399 CYS D C   1 
ATOM   17290 O O   . CYS D 1 399 ? 164.242 110.246 151.087 1.00 33.30  ? 399 CYS D O   1 
ATOM   17291 C CB  . CYS D 1 399 ? 165.633 108.815 148.466 1.00 27.96  ? 399 CYS D CB  1 
ATOM   17292 S SG  . CYS D 1 399 ? 166.145 107.164 147.949 1.00 38.78  ? 399 CYS D SG  1 
ATOM   17293 N N   . TYR D 1 400 ? 163.261 110.936 149.193 1.00 20.58  ? 400 TYR D N   1 
ATOM   17294 C CA  . TYR D 1 400 ? 162.781 112.189 149.773 1.00 14.04  ? 400 TYR D CA  1 
ATOM   17295 C C   . TYR D 1 400 ? 161.619 111.973 150.752 1.00 21.68  ? 400 TYR D C   1 
ATOM   17296 O O   . TYR D 1 400 ? 161.588 112.596 151.805 1.00 31.27  ? 400 TYR D O   1 
ATOM   17297 C CB  . TYR D 1 400 ? 162.443 113.205 148.677 1.00 11.33  ? 400 TYR D CB  1 
ATOM   17298 C CG  . TYR D 1 400 ? 162.367 114.627 149.204 1.00 20.38  ? 400 TYR D CG  1 
ATOM   17299 C CD1 . TYR D 1 400 ? 163.546 115.268 149.622 1.00 19.76  ? 400 TYR D CD1 1 
ATOM   17300 C CD2 . TYR D 1 400 ? 161.142 115.304 149.313 1.00 5.90   ? 400 TYR D CD2 1 
ATOM   17301 C CE1 . TYR D 1 400 ? 163.499 116.555 150.171 1.00 19.78  ? 400 TYR D CE1 1 
ATOM   17302 C CE2 . TYR D 1 400 ? 161.092 116.608 149.839 1.00 6.35   ? 400 TYR D CE2 1 
ATOM   17303 C CZ  . TYR D 1 400 ? 162.275 117.230 150.275 1.00 22.64  ? 400 TYR D CZ  1 
ATOM   17304 O OH  . TYR D 1 400 ? 162.270 118.481 150.799 1.00 31.03  ? 400 TYR D OH  1 
ATOM   17305 N N   . LEU D 1 401 ? 160.713 111.029 150.482 1.00 15.73  ? 401 LEU D N   1 
ATOM   17306 C CA  . LEU D 1 401 ? 159.696 110.595 151.439 1.00 18.62  ? 401 LEU D CA  1 
ATOM   17307 C C   . LEU D 1 401 ? 160.313 110.039 152.717 1.00 16.93  ? 401 LEU D C   1 
ATOM   17308 O O   . LEU D 1 401 ? 159.878 110.417 153.796 1.00 32.21  ? 401 LEU D O   1 
ATOM   17309 C CB  . LEU D 1 401 ? 158.799 109.497 150.843 1.00 25.57  ? 401 LEU D CB  1 
ATOM   17310 C CG  . LEU D 1 401 ? 157.521 109.961 150.149 1.00 24.97  ? 401 LEU D CG  1 
ATOM   17311 C CD1 . LEU D 1 401 ? 156.771 108.706 149.712 1.00 25.86  ? 401 LEU D CD1 1 
ATOM   17312 C CD2 . LEU D 1 401 ? 156.586 110.741 151.069 1.00 20.32  ? 401 LEU D CD2 1 
ATOM   17313 N N   . VAL D 1 402 ? 161.313 109.163 152.631 1.00 25.55  ? 402 VAL D N   1 
ATOM   17314 C CA  . VAL D 1 402 ? 161.982 108.609 153.814 1.00 22.25  ? 402 VAL D CA  1 
ATOM   17315 C C   . VAL D 1 402 ? 162.704 109.707 154.594 1.00 21.72  ? 402 VAL D C   1 
ATOM   17316 O O   . VAL D 1 402 ? 162.541 109.794 155.806 1.00 35.64  ? 402 VAL D O   1 
ATOM   17317 C CB  . VAL D 1 402 ? 162.914 107.451 153.424 1.00 26.62  ? 402 VAL D CB  1 
ATOM   17318 C CG1 . VAL D 1 402 ? 163.836 107.004 154.560 1.00 25.52  ? 402 VAL D CG1 1 
ATOM   17319 C CG2 . VAL D 1 402 ? 162.079 106.237 153.013 1.00 21.81  ? 402 VAL D CG2 1 
ATOM   17320 N N   . TYR D 1 403 ? 163.422 110.604 153.926 1.00 24.12  ? 403 TYR D N   1 
ATOM   17321 C CA  . TYR D 1 403 ? 164.004 111.781 154.562 1.00 20.00  ? 403 TYR D CA  1 
ATOM   17322 C C   . TYR D 1 403 ? 162.943 112.649 155.257 1.00 22.16  ? 403 TYR D C   1 
ATOM   17323 O O   . TYR D 1 403 ? 163.112 112.967 156.425 1.00 35.89  ? 403 TYR D O   1 
ATOM   17324 C CB  . TYR D 1 403 ? 164.836 112.542 153.524 1.00 20.24  ? 403 TYR D CB  1 
ATOM   17325 C CG  . TYR D 1 403 ? 165.260 113.944 153.905 1.00 26.76  ? 403 TYR D CG  1 
ATOM   17326 C CD1 . TYR D 1 403 ? 166.338 114.168 154.785 1.00 19.73  ? 403 TYR D CD1 1 
ATOM   17327 C CD2 . TYR D 1 403 ? 164.575 115.037 153.342 1.00 29.12  ? 403 TYR D CD2 1 
ATOM   17328 C CE1 . TYR D 1 403 ? 166.763 115.487 155.052 1.00 22.70  ? 403 TYR D CE1 1 
ATOM   17329 C CE2 . TYR D 1 403 ? 164.991 116.349 153.612 1.00 27.04  ? 403 TYR D CE2 1 
ATOM   17330 C CZ  . TYR D 1 403 ? 166.110 116.576 154.438 1.00 27.71  ? 403 TYR D CZ  1 
ATOM   17331 O OH  . TYR D 1 403 ? 166.578 117.843 154.598 1.00 37.47  ? 403 TYR D OH  1 
ATOM   17332 N N   . MET D 1 404 ? 161.820 112.974 154.617 1.00 23.17  ? 404 MET D N   1 
ATOM   17333 C CA  . MET D 1 404 ? 160.759 113.787 155.220 1.00 18.24  ? 404 MET D CA  1 
ATOM   17334 C C   . MET D 1 404 ? 159.944 113.079 156.300 1.00 18.31  ? 404 MET D C   1 
ATOM   17335 O O   . MET D 1 404 ? 159.491 113.728 157.241 1.00 27.92  ? 404 MET D O   1 
ATOM   17336 C CB  . MET D 1 404 ? 159.826 114.359 154.144 1.00 24.33  ? 404 MET D CB  1 
ATOM   17337 C CG  . MET D 1 404 ? 160.475 115.494 153.356 1.00 8.67   ? 404 MET D CG  1 
ATOM   17338 S SD  . MET D 1 404 ? 161.247 116.812 154.335 1.00 25.37  ? 404 MET D SD  1 
ATOM   17339 C CE  . MET D 1 404 ? 159.913 117.250 155.470 1.00 19.69  ? 404 MET D CE  1 
ATOM   17340 N N   . PHE D 1 405 ? 159.791 111.761 156.235 1.00 34.05  ? 405 PHE D N   1 
ATOM   17341 C CA  . PHE D 1 405 ? 159.255 110.954 157.326 1.00 19.76  ? 405 PHE D CA  1 
ATOM   17342 C C   . PHE D 1 405 ? 160.167 111.020 158.558 1.00 24.21  ? 405 PHE D C   1 
ATOM   17343 O O   . PHE D 1 405 ? 159.695 111.362 159.638 1.00 35.22  ? 405 PHE D O   1 
ATOM   17344 C CB  . PHE D 1 405 ? 159.053 109.516 156.844 1.00 22.76  ? 405 PHE D CB  1 
ATOM   17345 C CG  . PHE D 1 405 ? 158.628 108.567 157.939 1.00 37.81  ? 405 PHE D CG  1 
ATOM   17346 C CD1 . PHE D 1 405 ? 157.294 108.543 158.378 1.00 36.47  ? 405 PHE D CD1 1 
ATOM   17347 C CD2 . PHE D 1 405 ? 159.578 107.732 158.558 1.00 37.17  ? 405 PHE D CD2 1 
ATOM   17348 C CE1 . PHE D 1 405 ? 156.910 107.699 159.429 1.00 32.69  ? 405 PHE D CE1 1 
ATOM   17349 C CE2 . PHE D 1 405 ? 159.194 106.893 159.618 1.00 35.47  ? 405 PHE D CE2 1 
ATOM   17350 C CZ  . PHE D 1 405 ? 157.860 106.876 160.052 1.00 35.71  ? 405 PHE D CZ  1 
ATOM   17351 N N   . ILE D 1 406 ? 161.475 110.790 158.407 1.00 26.15  ? 406 ILE D N   1 
ATOM   17352 C CA  . ILE D 1 406 ? 162.450 110.927 159.501 1.00 25.43  ? 406 ILE D CA  1 
ATOM   17353 C C   . ILE D 1 406 ? 162.457 112.360 160.039 1.00 22.60  ? 406 ILE D C   1 
ATOM   17354 O O   . ILE D 1 406 ? 162.398 112.552 161.246 1.00 41.51  ? 406 ILE D O   1 
ATOM   17355 C CB  . ILE D 1 406 ? 163.856 110.466 159.055 1.00 32.73  ? 406 ILE D CB  1 
ATOM   17356 C CG1 . ILE D 1 406 ? 163.866 108.944 158.801 1.00 27.65  ? 406 ILE D CG1 1 
ATOM   17357 C CG2 . ILE D 1 406 ? 164.945 110.812 160.087 1.00 29.96  ? 406 ILE D CG2 1 
ATOM   17358 C CD1 . ILE D 1 406 ? 165.055 108.476 157.960 1.00 29.37  ? 406 ILE D CD1 1 
ATOM   17359 N N   . PHE D 1 407 ? 162.439 113.372 159.171 1.00 24.51  ? 407 PHE D N   1 
ATOM   17360 C CA  . PHE D 1 407 ? 162.350 114.779 159.553 1.00 19.44  ? 407 PHE D CA  1 
ATOM   17361 C C   . PHE D 1 407 ? 161.134 115.048 160.441 1.00 27.59  ? 407 PHE D C   1 
ATOM   17362 O O   . PHE D 1 407 ? 161.253 115.687 161.478 1.00 33.62  ? 407 PHE D O   1 
ATOM   17363 C CB  . PHE D 1 407 ? 162.315 115.651 158.287 1.00 21.91  ? 407 PHE D CB  1 
ATOM   17364 C CG  . PHE D 1 407 ? 162.969 117.010 158.406 1.00 26.88  ? 407 PHE D CG  1 
ATOM   17365 C CD1 . PHE D 1 407 ? 162.589 117.934 159.395 1.00 30.28  ? 407 PHE D CD1 1 
ATOM   17366 C CD2 . PHE D 1 407 ? 163.988 117.348 157.507 1.00 21.37  ? 407 PHE D CD2 1 
ATOM   17367 C CE1 . PHE D 1 407 ? 163.231 119.176 159.488 1.00 22.49  ? 407 PHE D CE1 1 
ATOM   17368 C CE2 . PHE D 1 407 ? 164.629 118.587 157.599 1.00 27.36  ? 407 PHE D CE2 1 
ATOM   17369 C CZ  . PHE D 1 407 ? 164.260 119.498 158.595 1.00 31.92  ? 407 PHE D CZ  1 
ATOM   17370 N N   . THR D 1 408 ? 159.969 114.526 160.068 1.00 29.24  ? 408 THR D N   1 
ATOM   17371 C CA  . THR D 1 408 ? 158.711 114.714 160.796 1.00 20.34  ? 408 THR D CA  1 
ATOM   17372 C C   . THR D 1 408 ? 158.711 114.004 162.138 1.00 25.95  ? 408 THR D C   1 
ATOM   17373 O O   . THR D 1 408 ? 158.360 114.613 163.142 1.00 41.51  ? 408 THR D O   1 
ATOM   17374 C CB  . THR D 1 408 ? 157.523 114.237 159.960 1.00 21.68  ? 408 THR D CB  1 
ATOM   17375 O OG1 . THR D 1 408 ? 157.564 114.872 158.720 1.00 29.67  ? 408 THR D OG1 1 
ATOM   17376 C CG2 . THR D 1 408 ? 156.176 114.574 160.576 1.00 22.10  ? 408 THR D CG2 1 
ATOM   17377 N N   . VAL D 1 409 ? 159.146 112.745 162.184 1.00 29.71  ? 409 VAL D N   1 
ATOM   17378 C CA  . VAL D 1 409 ? 159.286 111.984 163.427 1.00 28.52  ? 409 VAL D CA  1 
ATOM   17379 C C   . VAL D 1 409 ? 160.252 112.680 164.381 1.00 31.65  ? 409 VAL D C   1 
ATOM   17380 O O   . VAL D 1 409 ? 159.945 112.814 165.556 1.00 44.04  ? 409 VAL D O   1 
ATOM   17381 C CB  . VAL D 1 409 ? 159.721 110.537 163.138 1.00 30.59  ? 409 VAL D CB  1 
ATOM   17382 C CG1 . VAL D 1 409 ? 160.135 109.770 164.393 1.00 34.77  ? 409 VAL D CG1 1 
ATOM   17383 C CG2 . VAL D 1 409 ? 158.570 109.770 162.487 1.00 31.85  ? 409 VAL D CG2 1 
ATOM   17384 N N   . VAL D 1 410 ? 161.372 113.216 163.907 1.00 26.27  ? 410 VAL D N   1 
ATOM   17385 C CA  . VAL D 1 410 ? 162.343 113.935 164.742 1.00 32.22  ? 410 VAL D CA  1 
ATOM   17386 C C   . VAL D 1 410 ? 161.841 115.301 165.197 1.00 33.06  ? 410 VAL D C   1 
ATOM   17387 O O   . VAL D 1 410 ? 162.020 115.660 166.357 1.00 43.98  ? 410 VAL D O   1 
ATOM   17388 C CB  . VAL D 1 410 ? 163.674 114.070 163.991 1.00 34.58  ? 410 VAL D CB  1 
ATOM   17389 C CG1 . VAL D 1 410 ? 164.697 114.977 164.679 1.00 35.90  ? 410 VAL D CG1 1 
ATOM   17390 C CG2 . VAL D 1 410 ? 164.332 112.698 163.837 1.00 30.99  ? 410 VAL D CG2 1 
ATOM   17391 N N   . ALA D 1 411 ? 161.192 116.083 164.335 1.00 38.29  ? 411 ALA D N   1 
ATOM   17392 C CA  . ALA D 1 411 ? 160.641 117.382 164.716 1.00 35.52  ? 411 ALA D CA  1 
ATOM   17393 C C   . ALA D 1 411 ? 159.507 117.265 165.749 1.00 39.06  ? 411 ALA D C   1 
ATOM   17394 O O   . ALA D 1 411 ? 159.421 118.071 166.669 1.00 43.69  ? 411 ALA D O   1 
ATOM   17395 C CB  . ALA D 1 411 ? 160.180 118.099 163.449 1.00 35.36  ? 411 ALA D CB  1 
ATOM   17396 N N   . TYR D 1 412 ? 158.683 116.221 165.659 1.00 40.82  ? 412 TYR D N   1 
ATOM   17397 C CA  . TYR D 1 412 ? 157.609 115.952 166.608 1.00 37.29  ? 412 TYR D CA  1 
ATOM   17398 C C   . TYR D 1 412 ? 158.104 115.487 167.996 1.00 43.20  ? 412 TYR D C   1 
ATOM   17399 O O   . TYR D 1 412 ? 157.384 115.651 168.980 1.00 49.97  ? 412 TYR D O   1 
ATOM   17400 C CB  . TYR D 1 412 ? 156.661 114.939 165.965 1.00 38.24  ? 412 TYR D CB  1 
ATOM   17401 C CG  . TYR D 1 412 ? 155.386 114.684 166.743 1.00 45.39  ? 412 TYR D CG  1 
ATOM   17402 C CD1 . TYR D 1 412 ? 154.273 115.523 166.564 1.00 43.62  ? 412 TYR D CD1 1 
ATOM   17403 C CD2 . TYR D 1 412 ? 155.304 113.598 167.629 1.00 47.21  ? 412 TYR D CD2 1 
ATOM   17404 C CE1 . TYR D 1 412 ? 153.071 115.253 167.246 1.00 44.42  ? 412 TYR D CE1 1 
ATOM   17405 C CE2 . TYR D 1 412 ? 154.111 113.329 168.319 1.00 47.45  ? 412 TYR D CE2 1 
ATOM   17406 C CZ  . TYR D 1 412 ? 152.984 114.147 168.118 1.00 49.03  ? 412 TYR D CZ  1 
ATOM   17407 O OH  . TYR D 1 412 ? 151.837 113.880 168.793 1.00 49.61  ? 412 TYR D OH  1 
ATOM   17408 N N   . HIS D 1 413 ? 159.326 114.960 168.114 1.00 43.23  ? 413 HIS D N   1 
ATOM   17409 C CA  . HIS D 1 413 ? 159.908 114.438 169.360 1.00 42.12  ? 413 HIS D CA  1 
ATOM   17410 C C   . HIS D 1 413 ? 161.057 115.288 169.929 1.00 46.09  ? 413 HIS D C   1 
ATOM   17411 O O   . HIS D 1 413 ? 161.850 114.791 170.726 1.00 54.82  ? 413 HIS D O   1 
ATOM   17412 C CB  . HIS D 1 413 ? 160.294 112.960 169.203 1.00 40.56  ? 413 HIS D CB  1 
ATOM   17413 C CG  . HIS D 1 413 ? 159.135 112.041 168.942 1.00 41.51  ? 413 HIS D CG  1 
ATOM   17414 N ND1 . HIS D 1 413 ? 158.659 111.665 167.715 1.00 45.94  ? 413 HIS D ND1 1 
ATOM   17415 C CD2 . HIS D 1 413 ? 158.347 111.431 169.875 1.00 44.67  ? 413 HIS D CD2 1 
ATOM   17416 C CE1 . HIS D 1 413 ? 157.631 110.828 167.891 1.00 47.38  ? 413 HIS D CE1 1 
ATOM   17417 N NE2 . HIS D 1 413 ? 157.387 110.664 169.201 1.00 45.05  ? 413 HIS D NE2 1 
ATOM   17418 N N   . GLN D 1 414 ? 161.125 116.575 169.599 1.00 44.89  ? 414 GLN D N   1 
ATOM   17419 C CA  . GLN D 1 414 ? 162.067 117.499 170.231 1.00 48.82  ? 414 GLN D CA  1 
ATOM   17420 C C   . GLN D 1 414 ? 161.815 117.614 171.749 1.00 53.51  ? 414 GLN D C   1 
ATOM   17421 O O   . GLN D 1 414 ? 160.660 117.772 172.159 1.00 55.14  ? 414 GLN D O   1 
ATOM   17422 C CB  . GLN D 1 414 ? 161.955 118.889 169.589 1.00 49.37  ? 414 GLN D CB  1 
ATOM   17423 C CG  . GLN D 1 414 ? 162.367 118.886 168.114 1.00 48.87  ? 414 GLN D CG  1 
ATOM   17424 C CD  . GLN D 1 414 ? 163.821 118.508 167.915 1.00 52.71  ? 414 GLN D CD  1 
ATOM   17425 O OE1 . GLN D 1 414 ? 164.721 119.124 168.451 1.00 54.97  ? 414 GLN D OE1 1 
ATOM   17426 N NE2 . GLN D 1 414 ? 164.105 117.491 167.148 1.00 50.97  ? 414 GLN D NE2 1 
ATOM   17427 N N   . PRO D 1 415 ? 162.859 117.566 172.597 1.00 61.82  ? 415 PRO D N   1 
ATOM   17428 C CA  . PRO D 1 415 ? 162.725 117.758 174.038 1.00 61.01  ? 415 PRO D CA  1 
ATOM   17429 C C   . PRO D 1 415 ? 162.462 119.229 174.391 1.00 61.39  ? 415 PRO D C   1 
ATOM   17430 O O   . PRO D 1 415 ? 162.708 120.129 173.588 1.00 61.65  ? 415 PRO D O   1 
ATOM   17431 C CB  . PRO D 1 415 ? 164.049 117.257 174.625 1.00 60.53  ? 415 PRO D CB  1 
ATOM   17432 C CG  . PRO D 1 415 ? 165.057 117.582 173.528 1.00 59.50  ? 415 PRO D CG  1 
ATOM   17433 C CD  . PRO D 1 415 ? 164.257 117.348 172.249 1.00 59.05  ? 415 PRO D CD  1 
ATOM   17434 N N   . SER D 1 416 ? 162.001 119.484 175.616 1.00 66.75  ? 416 SER D N   1 
ATOM   17435 C CA  . SER D 1 416 ? 161.903 120.840 176.168 1.00 68.58  ? 416 SER D CA  1 
ATOM   17436 C C   . SER D 1 416 ? 163.284 121.504 176.272 1.00 70.01  ? 416 SER D C   1 
ATOM   17437 O O   . SER D 1 416 ? 164.282 120.837 176.556 1.00 69.71  ? 416 SER D O   1 
ATOM   17438 C CB  . SER D 1 416 ? 161.225 120.790 177.540 1.00 68.79  ? 416 SER D CB  1 
ATOM   17439 O OG  . SER D 1 416 ? 161.050 122.094 178.059 1.00 69.23  ? 416 SER D OG  1 
ATOM   17440 N N   . LEU D 1 417 ? 163.362 122.814 176.027 1.00 70.25  ? 417 LEU D N   1 
ATOM   17441 C CA  . LEU D 1 417 ? 164.626 123.557 175.988 1.00 71.33  ? 417 LEU D CA  1 
ATOM   17442 C C   . LEU D 1 417 ? 165.163 123.886 177.392 1.00 71.83  ? 417 LEU D C   1 
ATOM   17443 O O   . LEU D 1 417 ? 164.461 124.443 178.242 1.00 69.22  ? 417 LEU D O   1 
ATOM   17444 C CB  . LEU D 1 417 ? 164.499 124.815 175.107 1.00 69.38  ? 417 LEU D CB  1 
ATOM   17445 C CG  . LEU D 1 417 ? 163.945 124.574 173.687 1.00 70.14  ? 417 LEU D CG  1 
ATOM   17446 C CD1 . LEU D 1 417 ? 164.150 125.822 172.832 1.00 71.08  ? 417 LEU D CD1 1 
ATOM   17447 C CD2 . LEU D 1 417 ? 164.637 123.419 172.973 1.00 70.39  ? 417 LEU D CD2 1 
ATOM   17448 N N   . PHE D 1 429 ? 166.947 104.505 175.217 1.00 75.29  ? 429 PHE D N   1 
ATOM   17449 C CA  . PHE D 1 429 ? 166.979 104.091 173.817 1.00 76.49  ? 429 PHE D CA  1 
ATOM   17450 C C   . PHE D 1 429 ? 166.441 105.178 172.879 1.00 76.10  ? 429 PHE D C   1 
ATOM   17451 O O   . PHE D 1 429 ? 167.097 105.522 171.891 1.00 76.57  ? 429 PHE D O   1 
ATOM   17452 C CB  . PHE D 1 429 ? 166.176 102.792 173.662 1.00 75.45  ? 429 PHE D CB  1 
ATOM   17453 C CG  . PHE D 1 429 ? 165.938 102.372 172.223 1.00 75.47  ? 429 PHE D CG  1 
ATOM   17454 C CD1 . PHE D 1 429 ? 167.013 101.926 171.435 1.00 74.70  ? 429 PHE D CD1 1 
ATOM   17455 C CD2 . PHE D 1 429 ? 164.643 102.418 171.671 1.00 76.37  ? 429 PHE D CD2 1 
ATOM   17456 C CE1 . PHE D 1 429 ? 166.791 101.503 170.114 1.00 75.62  ? 429 PHE D CE1 1 
ATOM   17457 C CE2 . PHE D 1 429 ? 164.422 101.994 170.354 1.00 75.86  ? 429 PHE D CE2 1 
ATOM   17458 C CZ  . PHE D 1 429 ? 165.497 101.525 169.578 1.00 75.61  ? 429 PHE D CZ  1 
ATOM   17459 N N   . GLY D 1 430 ? 165.295 105.770 173.210 1.00 75.31  ? 430 GLY D N   1 
ATOM   17460 C CA  . GLY D 1 430 ? 164.634 106.797 172.402 1.00 73.39  ? 430 GLY D CA  1 
ATOM   17461 C C   . GLY D 1 430 ? 165.480 108.059 172.215 1.00 73.23  ? 430 GLY D C   1 
ATOM   17462 O O   . GLY D 1 430 ? 165.467 108.652 171.139 1.00 75.17  ? 430 GLY D O   1 
ATOM   17463 N N   . GLU D 1 431 ? 166.301 108.426 173.198 1.00 70.66  ? 431 GLU D N   1 
ATOM   17464 C CA  . GLU D 1 431 ? 167.266 109.521 173.076 1.00 69.47  ? 431 GLU D CA  1 
ATOM   17465 C C   . GLU D 1 431 ? 168.382 109.227 172.064 1.00 70.48  ? 431 GLU D C   1 
ATOM   17466 O O   . GLU D 1 431 ? 168.813 110.127 171.345 1.00 71.10  ? 431 GLU D O   1 
ATOM   17467 C CB  . GLU D 1 431 ? 167.861 109.795 174.455 1.00 68.59  ? 431 GLU D CB  1 
ATOM   17468 N N   . SER D 1 432 ? 168.818 107.967 171.937 1.00 70.20  ? 432 SER D N   1 
ATOM   17469 C CA  . SER D 1 432 ? 169.800 107.559 170.920 1.00 70.70  ? 432 SER D CA  1 
ATOM   17470 C C   . SER D 1 432 ? 169.198 107.534 169.509 1.00 70.93  ? 432 SER D C   1 
ATOM   17471 O O   . SER D 1 432 ? 169.816 108.005 168.561 1.00 70.10  ? 432 SER D O   1 
ATOM   17472 C CB  . SER D 1 432 ? 170.440 106.212 171.287 1.00 71.11  ? 432 SER D CB  1 
ATOM   17473 O OG  . SER D 1 432 ? 169.621 105.098 170.981 1.00 73.10  ? 432 SER D OG  1 
ATOM   17474 N N   . MET D 1 433 ? 167.948 107.078 169.366 1.00 67.85  ? 433 MET D N   1 
ATOM   17475 C CA  . MET D 1 433 ? 167.217 107.149 168.100 1.00 65.56  ? 433 MET D CA  1 
ATOM   17476 C C   . MET D 1 433 ? 166.918 108.589 167.677 1.00 65.22  ? 433 MET D C   1 
ATOM   17477 O O   . MET D 1 433 ? 166.976 108.902 166.491 1.00 68.18  ? 433 MET D O   1 
ATOM   17478 C CB  . MET D 1 433 ? 165.923 106.328 168.189 1.00 65.66  ? 433 MET D CB  1 
ATOM   17479 C CG  . MET D 1 433 ? 166.202 104.835 168.016 1.00 68.60  ? 433 MET D CG  1 
ATOM   17480 S SD  . MET D 1 433 ? 166.782 104.421 166.349 1.00 78.83  ? 433 MET D SD  1 
ATOM   17481 C CE  . MET D 1 433 ? 167.074 102.648 166.534 1.00 67.37  ? 433 MET D CE  1 
ATOM   17482 N N   . LEU D 1 434 ? 166.674 109.497 168.622 1.00 56.02  ? 434 LEU D N   1 
ATOM   17483 C CA  . LEU D 1 434 ? 166.536 110.919 168.329 1.00 56.03  ? 434 LEU D CA  1 
ATOM   17484 C C   . LEU D 1 434 ? 167.863 111.545 167.863 1.00 58.14  ? 434 LEU D C   1 
ATOM   17485 O O   . LEU D 1 434 ? 167.857 112.333 166.923 1.00 60.37  ? 434 LEU D O   1 
ATOM   17486 C CB  . LEU D 1 434 ? 165.942 111.632 169.556 1.00 57.75  ? 434 LEU D CB  1 
ATOM   17487 C CG  . LEU D 1 434 ? 165.556 113.093 169.283 1.00 57.04  ? 434 LEU D CG  1 
ATOM   17488 C CD1 . LEU D 1 434 ? 164.376 113.212 168.316 1.00 56.19  ? 434 LEU D CD1 1 
ATOM   17489 C CD2 . LEU D 1 434 ? 165.172 113.788 170.578 1.00 56.70  ? 434 LEU D CD2 1 
ATOM   17490 N N   . LEU D 1 435 ? 169.005 111.178 168.455 1.00 57.91  ? 435 LEU D N   1 
ATOM   17491 C CA  . LEU D 1 435 ? 170.333 111.587 167.973 1.00 59.40  ? 435 LEU D CA  1 
ATOM   17492 C C   . LEU D 1 435 ? 170.620 111.064 166.555 1.00 58.86  ? 435 LEU D C   1 
ATOM   17493 O O   . LEU D 1 435 ? 171.059 111.829 165.699 1.00 56.11  ? 435 LEU D O   1 
ATOM   17494 C CB  . LEU D 1 435 ? 171.398 111.117 168.977 1.00 61.73  ? 435 LEU D CB  1 
ATOM   17495 C CG  . LEU D 1 435 ? 172.853 111.398 168.563 1.00 60.67  ? 435 LEU D CG  1 
ATOM   17496 C CD1 . LEU D 1 435 ? 173.155 112.893 168.529 1.00 57.75  ? 435 LEU D CD1 1 
ATOM   17497 C CD2 . LEU D 1 435 ? 173.804 110.727 169.546 1.00 60.66  ? 435 LEU D CD2 1 
ATOM   17498 N N   . LEU D 1 436 ? 170.319 109.789 166.285 1.00 52.84  ? 436 LEU D N   1 
ATOM   17499 C CA  . LEU D 1 436 ? 170.436 109.206 164.948 1.00 50.75  ? 436 LEU D CA  1 
ATOM   17500 C C   . LEU D 1 436 ? 169.580 109.982 163.934 1.00 53.43  ? 436 LEU D C   1 
ATOM   17501 O O   . LEU D 1 436 ? 170.062 110.359 162.871 1.00 54.14  ? 436 LEU D O   1 
ATOM   17502 C CB  . LEU D 1 436 ? 170.056 107.714 164.997 1.00 50.72  ? 436 LEU D CB  1 
ATOM   17503 C CG  . LEU D 1 436 ? 170.089 107.020 163.623 1.00 51.81  ? 436 LEU D CG  1 
ATOM   17504 C CD1 . LEU D 1 436 ? 171.494 107.005 163.022 1.00 53.49  ? 436 LEU D CD1 1 
ATOM   17505 C CD2 . LEU D 1 436 ? 169.608 105.579 163.748 1.00 49.99  ? 436 LEU D CD2 1 
ATOM   17506 N N   . GLY D 1 437 ? 168.335 110.295 164.286 1.00 46.77  ? 437 GLY D N   1 
ATOM   17507 C CA  . GLY D 1 437 ? 167.455 111.115 163.465 1.00 41.77  ? 437 GLY D CA  1 
ATOM   17508 C C   . GLY D 1 437 ? 168.010 112.507 163.157 1.00 42.20  ? 437 GLY D C   1 
ATOM   17509 O O   . GLY D 1 437 ? 167.917 112.956 162.020 1.00 49.59  ? 437 GLY D O   1 
ATOM   17510 N N   . HIS D 1 438 ? 168.650 113.185 164.110 1.00 40.39  ? 438 HIS D N   1 
ATOM   17511 C CA  . HIS D 1 438 ? 169.292 114.478 163.844 1.00 43.77  ? 438 HIS D CA  1 
ATOM   17512 C C   . HIS D 1 438 ? 170.481 114.384 162.884 1.00 47.43  ? 438 HIS D C   1 
ATOM   17513 O O   . HIS D 1 438 ? 170.603 115.227 161.999 1.00 49.93  ? 438 HIS D O   1 
ATOM   17514 C CB  . HIS D 1 438 ? 169.732 115.159 165.142 1.00 48.39  ? 438 HIS D CB  1 
ATOM   17515 C CG  . HIS D 1 438 ? 168.595 115.739 165.932 1.00 48.02  ? 438 HIS D CG  1 
ATOM   17516 N ND1 . HIS D 1 438 ? 167.883 115.112 166.917 1.00 49.15  ? 438 HIS D ND1 1 
ATOM   17517 C CD2 . HIS D 1 438 ? 168.033 116.970 165.757 1.00 46.70  ? 438 HIS D CD2 1 
ATOM   17518 C CE1 . HIS D 1 438 ? 166.934 115.948 167.352 1.00 49.90  ? 438 HIS D CE1 1 
ATOM   17519 N NE2 . HIS D 1 438 ? 166.984 117.099 166.667 1.00 50.94  ? 438 HIS D NE2 1 
ATOM   17520 N N   . ILE D 1 439 ? 171.345 113.373 162.998 1.00 47.25  ? 439 ILE D N   1 
ATOM   17521 C CA  . ILE D 1 439 ? 172.465 113.230 162.057 1.00 45.54  ? 439 ILE D CA  1 
ATOM   17522 C C   . ILE D 1 439 ? 172.000 112.740 160.678 1.00 44.21  ? 439 ILE D C   1 
ATOM   17523 O O   . ILE D 1 439 ? 172.548 113.192 159.680 1.00 44.65  ? 439 ILE D O   1 
ATOM   17524 C CB  . ILE D 1 439 ? 173.644 112.421 162.634 1.00 49.87  ? 439 ILE D CB  1 
ATOM   17525 C CG1 . ILE D 1 439 ? 173.296 110.951 162.908 1.00 49.05  ? 439 ILE D CG1 1 
ATOM   17526 C CG2 . ILE D 1 439 ? 174.183 113.132 163.884 1.00 46.25  ? 439 ILE D CG2 1 
ATOM   17527 C CD1 . ILE D 1 439 ? 174.450 110.116 163.452 1.00 49.34  ? 439 ILE D CD1 1 
ATOM   17528 N N   . LEU D 1 440 ? 170.946 111.922 160.570 1.00 38.85  ? 440 LEU D N   1 
ATOM   17529 C CA  . LEU D 1 440 ? 170.314 111.619 159.281 1.00 37.92  ? 440 LEU D CA  1 
ATOM   17530 C C   . LEU D 1 440 ? 169.707 112.868 158.624 1.00 34.57  ? 440 LEU D C   1 
ATOM   17531 O O   . LEU D 1 440 ? 169.852 113.048 157.421 1.00 45.17  ? 440 LEU D O   1 
ATOM   17532 C CB  . LEU D 1 440 ? 169.262 110.508 159.449 1.00 41.19  ? 440 LEU D CB  1 
ATOM   17533 C CG  . LEU D 1 440 ? 169.838 109.124 159.803 1.00 40.88  ? 440 LEU D CG  1 
ATOM   17534 C CD1 . LEU D 1 440 ? 168.697 108.149 160.052 1.00 36.05  ? 440 LEU D CD1 1 
ATOM   17535 C CD2 . LEU D 1 440 ? 170.710 108.540 158.701 1.00 41.82  ? 440 LEU D CD2 1 
ATOM   17536 N N   . ILE D 1 441 ? 169.084 113.768 159.388 1.00 33.24  ? 441 ILE D N   1 
ATOM   17537 C CA  . ILE D 1 441 ? 168.589 115.063 158.888 1.00 35.26  ? 441 ILE D CA  1 
ATOM   17538 C C   . ILE D 1 441 ? 169.737 115.985 158.475 1.00 35.49  ? 441 ILE D C   1 
ATOM   17539 O O   . ILE D 1 441 ? 169.656 116.618 157.429 1.00 42.52  ? 441 ILE D O   1 
ATOM   17540 C CB  . ILE D 1 441 ? 167.681 115.724 159.946 1.00 40.87  ? 441 ILE D CB  1 
ATOM   17541 C CG1 . ILE D 1 441 ? 166.340 114.981 159.953 1.00 33.92  ? 441 ILE D CG1 1 
ATOM   17542 C CG2 . ILE D 1 441 ? 167.427 117.222 159.722 1.00 39.97  ? 441 ILE D CG2 1 
ATOM   17543 C CD1 . ILE D 1 441 ? 165.566 115.250 161.231 1.00 41.73  ? 441 ILE D CD1 1 
ATOM   17544 N N   . LEU D 1 442 ? 170.826 116.037 159.242 1.00 33.96  ? 442 LEU D N   1 
ATOM   17545 C CA  . LEU D 1 442 ? 172.029 116.782 158.870 1.00 34.35  ? 442 LEU D CA  1 
ATOM   17546 C C   . LEU D 1 442 ? 172.640 116.267 157.558 1.00 36.95  ? 442 LEU D C   1 
ATOM   17547 O O   . LEU D 1 442 ? 172.885 117.050 156.649 1.00 41.91  ? 442 LEU D O   1 
ATOM   17548 C CB  . LEU D 1 442 ? 173.038 116.724 160.027 1.00 36.29  ? 442 LEU D CB  1 
ATOM   17549 C CG  . LEU D 1 442 ? 174.366 117.444 159.755 1.00 36.85  ? 442 LEU D CG  1 
ATOM   17550 C CD1 . LEU D 1 442 ? 174.186 118.920 159.425 1.00 35.73  ? 442 LEU D CD1 1 
ATOM   17551 C CD2 . LEU D 1 442 ? 175.249 117.340 160.988 1.00 36.20  ? 442 LEU D CD2 1 
ATOM   17552 N N   . LEU D 1 443 ? 172.849 114.958 157.428 1.00 38.27  ? 443 LEU D N   1 
ATOM   17553 C CA  . LEU D 1 443 ? 173.423 114.340 156.232 1.00 36.53  ? 443 LEU D CA  1 
ATOM   17554 C C   . LEU D 1 443 ? 172.510 114.473 155.013 1.00 33.14  ? 443 LEU D C   1 
ATOM   17555 O O   . LEU D 1 443 ? 172.992 114.833 153.944 1.00 42.78  ? 443 LEU D O   1 
ATOM   17556 C CB  . LEU D 1 443 ? 173.738 112.862 156.508 1.00 38.93  ? 443 LEU D CB  1 
ATOM   17557 C CG  . LEU D 1 443 ? 174.896 112.638 157.492 1.00 39.46  ? 443 LEU D CG  1 
ATOM   17558 C CD1 . LEU D 1 443 ? 174.954 111.159 157.853 1.00 37.38  ? 443 LEU D CD1 1 
ATOM   17559 C CD2 . LEU D 1 443 ? 176.246 113.043 156.903 1.00 37.28  ? 443 LEU D CD2 1 
ATOM   17560 N N   . GLY D 1 444 ? 171.200 114.262 155.161 1.00 27.99  ? 444 GLY D N   1 
ATOM   17561 C CA  . GLY D 1 444 ? 170.224 114.518 154.104 1.00 21.98  ? 444 GLY D CA  1 
ATOM   17562 C C   . GLY D 1 444 ? 170.168 115.986 153.690 1.00 23.34  ? 444 GLY D C   1 
ATOM   17563 O O   . GLY D 1 444 ? 170.127 116.286 152.504 1.00 36.02  ? 444 GLY D O   1 
ATOM   17564 N N   . GLY D 1 445 ? 170.272 116.910 154.641 1.00 29.28  ? 445 GLY D N   1 
ATOM   17565 C CA  . GLY D 1 445 ? 170.391 118.338 154.376 1.00 29.43  ? 445 GLY D CA  1 
ATOM   17566 C C   . GLY D 1 445 ? 171.667 118.707 153.627 1.00 28.20  ? 445 GLY D C   1 
ATOM   17567 O O   . GLY D 1 445 ? 171.594 119.439 152.650 1.00 36.99  ? 445 GLY D O   1 
ATOM   17568 N N   . ILE D 1 446 ? 172.826 118.172 154.016 1.00 33.74  ? 446 ILE D N   1 
ATOM   17569 C CA  . ILE D 1 446 ? 174.094 118.369 153.298 1.00 33.25  ? 446 ILE D CA  1 
ATOM   17570 C C   . ILE D 1 446 ? 174.018 117.771 151.890 1.00 33.32  ? 446 ILE D C   1 
ATOM   17571 O O   . ILE D 1 446 ? 174.376 118.437 150.927 1.00 35.91  ? 446 ILE D O   1 
ATOM   17572 C CB  . ILE D 1 446 ? 175.282 117.791 154.103 1.00 34.57  ? 446 ILE D CB  1 
ATOM   17573 C CG1 . ILE D 1 446 ? 175.536 118.635 155.368 1.00 30.51  ? 446 ILE D CG1 1 
ATOM   17574 C CG2 . ILE D 1 446 ? 176.570 117.737 153.262 1.00 30.88  ? 446 ILE D CG2 1 
ATOM   17575 C CD1 . ILE D 1 446 ? 176.383 117.906 156.416 1.00 31.51  ? 446 ILE D CD1 1 
ATOM   17576 N N   . TYR D 1 447 ? 173.511 116.551 151.738 1.00 26.21  ? 447 TYR D N   1 
ATOM   17577 C CA  . TYR D 1 447 ? 173.362 115.898 150.444 1.00 23.97  ? 447 TYR D CA  1 
ATOM   17578 C C   . TYR D 1 447 ? 172.478 116.694 149.479 1.00 32.00  ? 447 TYR D C   1 
ATOM   17579 O O   . TYR D 1 447 ? 172.867 116.933 148.338 1.00 47.99  ? 447 TYR D O   1 
ATOM   17580 C CB  . TYR D 1 447 ? 172.780 114.505 150.665 1.00 27.58  ? 447 TYR D CB  1 
ATOM   17581 C CG  . TYR D 1 447 ? 172.590 113.727 149.385 1.00 39.32  ? 447 TYR D CG  1 
ATOM   17582 C CD1 . TYR D 1 447 ? 173.644 112.938 148.905 1.00 32.78  ? 447 TYR D CD1 1 
ATOM   17583 C CD2 . TYR D 1 447 ? 171.387 113.816 148.655 1.00 35.10  ? 447 TYR D CD2 1 
ATOM   17584 C CE1 . TYR D 1 447 ? 173.497 112.223 147.713 1.00 34.84  ? 447 TYR D CE1 1 
ATOM   17585 C CE2 . TYR D 1 447 ? 171.241 113.107 147.449 1.00 34.28  ? 447 TYR D CE2 1 
ATOM   17586 C CZ  . TYR D 1 447 ? 172.300 112.310 146.978 1.00 38.42  ? 447 TYR D CZ  1 
ATOM   17587 O OH  . TYR D 1 447 ? 172.189 111.642 145.807 1.00 40.61  ? 447 TYR D OH  1 
ATOM   17588 N N   . LEU D 1 448 ? 171.309 117.142 149.932 1.00 18.73  ? 448 LEU D N   1 
ATOM   17589 C CA  . LEU D 1 448 ? 170.415 117.973 149.135 1.00 19.00  ? 448 LEU D CA  1 
ATOM   17590 C C   . LEU D 1 448 ? 171.038 119.333 148.824 1.00 24.44  ? 448 LEU D C   1 
ATOM   17591 O O   . LEU D 1 448 ? 170.920 119.807 147.699 1.00 31.24  ? 448 LEU D O   1 
ATOM   17592 C CB  . LEU D 1 448 ? 169.078 118.130 149.867 1.00 23.73  ? 448 LEU D CB  1 
ATOM   17593 C CG  . LEU D 1 448 ? 168.251 116.839 149.914 1.00 30.49  ? 448 LEU D CG  1 
ATOM   17594 C CD1 . LEU D 1 448 ? 167.168 116.979 150.971 1.00 27.41  ? 448 LEU D CD1 1 
ATOM   17595 C CD2 . LEU D 1 448 ? 167.585 116.531 148.577 1.00 31.78  ? 448 LEU D CD2 1 
ATOM   17596 N N   . LEU D 1 449 ? 171.750 119.942 149.771 1.00 28.61  ? 449 LEU D N   1 
ATOM   17597 C CA  . LEU D 1 449 ? 172.459 121.202 149.581 1.00 29.67  ? 449 LEU D CA  1 
ATOM   17598 C C   . LEU D 1 449 ? 173.540 121.069 148.501 1.00 27.67  ? 449 LEU D C   1 
ATOM   17599 O O   . LEU D 1 449 ? 173.549 121.852 147.562 1.00 33.28  ? 449 LEU D O   1 
ATOM   17600 C CB  . LEU D 1 449 ? 173.025 121.665 150.936 1.00 33.70  ? 449 LEU D CB  1 
ATOM   17601 C CG  . LEU D 1 449 ? 173.817 122.972 150.918 1.00 31.24  ? 449 LEU D CG  1 
ATOM   17602 C CD1 . LEU D 1 449 ? 172.967 124.125 150.412 1.00 28.21  ? 449 LEU D CD1 1 
ATOM   17603 C CD2 . LEU D 1 449 ? 174.283 123.295 152.331 1.00 29.05  ? 449 LEU D CD2 1 
ATOM   17604 N N   . LEU D 1 450 ? 174.395 120.047 148.570 1.00 32.41  ? 450 LEU D N   1 
ATOM   17605 C CA  . LEU D 1 450 ? 175.422 119.782 147.559 1.00 30.01  ? 450 LEU D CA  1 
ATOM   17606 C C   . LEU D 1 450 ? 174.811 119.499 146.188 1.00 28.05  ? 450 LEU D C   1 
ATOM   17607 O O   . LEU D 1 450 ? 175.250 120.078 145.199 1.00 41.04  ? 450 LEU D O   1 
ATOM   17608 C CB  . LEU D 1 450 ? 176.312 118.612 148.004 1.00 29.88  ? 450 LEU D CB  1 
ATOM   17609 C CG  . LEU D 1 450 ? 177.204 118.929 149.213 1.00 31.33  ? 450 LEU D CG  1 
ATOM   17610 C CD1 . LEU D 1 450 ? 177.886 117.653 149.686 1.00 30.20  ? 450 LEU D CD1 1 
ATOM   17611 C CD2 . LEU D 1 450 ? 178.284 119.952 148.886 1.00 29.99  ? 450 LEU D CD2 1 
ATOM   17612 N N   . GLY D 1 451 ? 173.763 118.680 146.119 1.00 26.14  ? 451 GLY D N   1 
ATOM   17613 C CA  . GLY D 1 451 ? 173.068 118.397 144.869 1.00 19.13  ? 451 GLY D CA  1 
ATOM   17614 C C   . GLY D 1 451 ? 172.443 119.631 144.220 1.00 23.95  ? 451 GLY D C   1 
ATOM   17615 O O   . GLY D 1 451 ? 172.457 119.762 143.000 1.00 37.48  ? 451 GLY D O   1 
ATOM   17616 N N   . GLN D 1 452 ? 171.963 120.560 145.050 1.00 27.07  ? 452 GLN D N   1 
ATOM   17617 C CA  . GLN D 1 452 ? 171.297 121.783 144.519 1.00 25.63  ? 452 GLN D CA  1 
ATOM   17618 C C   . GLN D 1 452 ? 172.368 122.815 144.130 1.00 27.30  ? 452 GLN D C   1 
ATOM   17619 O O   . GLN D 1 452 ? 172.231 123.400 143.037 1.00 39.57  ? 452 GLN D O   1 
ATOM   17620 C CB  . GLN D 1 452 ? 170.224 122.226 145.521 1.00 30.95  ? 452 GLN D CB  1 
ATOM   17621 C CG  . GLN D 1 452 ? 169.047 121.240 145.546 1.00 27.79  ? 452 GLN D CG  1 
ATOM   17622 C CD  . GLN D 1 452 ? 168.148 121.398 144.344 1.00 28.95  ? 452 GLN D CD  1 
ATOM   17623 O OE1 . GLN D 1 452 ? 168.263 122.354 143.579 1.00 36.07  ? 452 GLN D OE1 1 
ATOM   17624 N NE2 . GLN D 1 452 ? 167.234 120.458 144.173 1.00 39.24  ? 452 GLN D NE2 1 
ATOM   17625 N N   . LEU D 1 453 ? 173.391 123.031 144.965 1.00 32.99  ? 453 LEU D N   1 
ATOM   17626 C CA  . LEU D 1 453 ? 174.501 123.905 144.581 1.00 31.52  ? 453 LEU D CA  1 
ATOM   17627 C C   . LEU D 1 453 ? 175.141 123.435 143.271 1.00 29.21  ? 453 LEU D C   1 
ATOM   17628 O O   . LEU D 1 453 ? 175.462 124.251 142.415 1.00 37.05  ? 453 LEU D O   1 
ATOM   17629 C CB  . LEU D 1 453 ? 175.544 123.966 145.710 1.00 32.78  ? 453 LEU D CB  1 
ATOM   17630 C CG  . LEU D 1 453 ? 175.068 124.675 146.984 1.00 32.27  ? 453 LEU D CG  1 
ATOM   17631 C CD1 . LEU D 1 453 ? 176.118 124.500 148.074 1.00 32.35  ? 453 LEU D CD1 1 
ATOM   17632 C CD2 . LEU D 1 453 ? 174.837 126.167 146.769 1.00 29.54  ? 453 LEU D CD2 1 
ATOM   17633 N N   . TRP D 1 454 ? 175.266 122.121 143.074 1.00 30.12  ? 454 TRP D N   1 
ATOM   17634 C CA  . TRP D 1 454 ? 175.719 121.531 141.819 1.00 29.15  ? 454 TRP D CA  1 
ATOM   17635 C C   . TRP D 1 454 ? 174.762 121.793 140.648 1.00 29.78  ? 454 TRP D C   1 
ATOM   17636 O O   . TRP D 1 454 ? 175.226 122.128 139.563 1.00 41.71  ? 454 TRP D O   1 
ATOM   17637 C CB  . TRP D 1 454 ? 175.964 120.037 142.030 1.00 29.99  ? 454 TRP D CB  1 
ATOM   17638 C CG  . TRP D 1 454 ? 176.458 119.283 140.837 1.00 39.68  ? 454 TRP D CG  1 
ATOM   17639 C CD1 . TRP D 1 454 ? 177.639 119.496 140.213 1.00 38.20  ? 454 TRP D CD1 1 
ATOM   17640 C CD2 . TRP D 1 454 ? 175.820 118.192 140.109 1.00 38.97  ? 454 TRP D CD2 1 
ATOM   17641 N NE1 . TRP D 1 454 ? 177.782 118.601 139.174 1.00 33.21  ? 454 TRP D NE1 1 
ATOM   17642 C CE2 . TRP D 1 454 ? 176.704 117.755 139.084 1.00 37.17  ? 454 TRP D CE2 1 
ATOM   17643 C CE3 . TRP D 1 454 ? 174.580 117.523 140.215 1.00 34.63  ? 454 TRP D CE3 1 
ATOM   17644 C CZ2 . TRP D 1 454 ? 176.386 116.701 138.218 1.00 40.94  ? 454 TRP D CZ2 1 
ATOM   17645 C CZ3 . TRP D 1 454 ? 174.261 116.450 139.363 1.00 41.27  ? 454 TRP D CZ3 1 
ATOM   17646 C CH2 . TRP D 1 454 ? 175.161 116.033 138.368 1.00 38.92  ? 454 TRP D CH2 1 
ATOM   17647 N N   . TYR D 1 455 ? 173.443 121.744 140.851 1.00 35.86  ? 455 TYR D N   1 
ATOM   17648 C CA  . TYR D 1 455 ? 172.469 122.162 139.840 1.00 32.60  ? 455 TYR D CA  1 
ATOM   17649 C C   . TYR D 1 455 ? 172.696 123.612 139.405 1.00 32.49  ? 455 TYR D C   1 
ATOM   17650 O O   . TYR D 1 455 ? 172.887 123.881 138.221 1.00 40.82  ? 455 TYR D O   1 
ATOM   17651 C CB  . TYR D 1 455 ? 171.031 121.970 140.344 1.00 34.39  ? 455 TYR D CB  1 
ATOM   17652 C CG  . TYR D 1 455 ? 169.976 122.474 139.376 1.00 36.31  ? 455 TYR D CG  1 
ATOM   17653 C CD1 . TYR D 1 455 ? 169.516 121.638 138.344 1.00 33.92  ? 455 TYR D CD1 1 
ATOM   17654 C CD2 . TYR D 1 455 ? 169.488 123.792 139.469 1.00 33.24  ? 455 TYR D CD2 1 
ATOM   17655 C CE1 . TYR D 1 455 ? 168.578 122.109 137.412 1.00 33.68  ? 455 TYR D CE1 1 
ATOM   17656 C CE2 . TYR D 1 455 ? 168.565 124.278 138.527 1.00 37.03  ? 455 TYR D CE2 1 
ATOM   17657 C CZ  . TYR D 1 455 ? 168.096 123.429 137.501 1.00 40.58  ? 455 TYR D CZ  1 
ATOM   17658 O OH  . TYR D 1 455 ? 167.170 123.865 136.607 1.00 41.54  ? 455 TYR D OH  1 
ATOM   17659 N N   . PHE D 1 456 ? 172.738 124.555 140.346 1.00 33.35  ? 456 PHE D N   1 
ATOM   17660 C CA  . PHE D 1 456 ? 172.942 125.961 140.009 1.00 31.80  ? 456 PHE D CA  1 
ATOM   17661 C C   . PHE D 1 456 ? 174.331 126.260 139.445 1.00 37.82  ? 456 PHE D C   1 
ATOM   17662 O O   . PHE D 1 456 ? 174.448 127.152 138.613 1.00 44.84  ? 456 PHE D O   1 
ATOM   17663 C CB  . PHE D 1 456 ? 172.599 126.848 141.204 1.00 33.13  ? 456 PHE D CB  1 
ATOM   17664 C CG  . PHE D 1 456 ? 171.110 126.926 141.460 1.00 37.52  ? 456 PHE D CG  1 
ATOM   17665 C CD1 . PHE D 1 456 ? 170.262 127.450 140.468 1.00 39.77  ? 456 PHE D CD1 1 
ATOM   17666 C CD2 . PHE D 1 456 ? 170.565 126.453 142.664 1.00 34.64  ? 456 PHE D CD2 1 
ATOM   17667 C CE1 . PHE D 1 456 ? 168.876 127.497 140.674 1.00 38.82  ? 456 PHE D CE1 1 
ATOM   17668 C CE2 . PHE D 1 456 ? 169.178 126.504 142.872 1.00 32.52  ? 456 PHE D CE2 1 
ATOM   17669 C CZ  . PHE D 1 456 ? 168.336 127.027 141.879 1.00 36.83  ? 456 PHE D CZ  1 
ATOM   17670 N N   . TRP D 1 457 ? 175.367 125.498 139.797 1.00 39.02  ? 457 TRP D N   1 
ATOM   17671 C CA  . TRP D 1 457 ? 176.663 125.575 139.127 1.00 38.16  ? 457 TRP D CA  1 
ATOM   17672 C C   . TRP D 1 457 ? 176.595 125.117 137.667 1.00 43.87  ? 457 TRP D C   1 
ATOM   17673 O O   . TRP D 1 457 ? 177.026 125.838 136.768 1.00 48.05  ? 457 TRP D O   1 
ATOM   17674 C CB  . TRP D 1 457 ? 177.711 124.774 139.895 1.00 44.26  ? 457 TRP D CB  1 
ATOM   17675 C CG  . TRP D 1 457 ? 179.077 124.888 139.300 1.00 48.56  ? 457 TRP D CG  1 
ATOM   17676 C CD1 . TRP D 1 457 ? 179.757 123.901 138.678 1.00 47.80  ? 457 TRP D CD1 1 
ATOM   17677 C CD2 . TRP D 1 457 ? 179.933 126.068 139.244 1.00 45.67  ? 457 TRP D CD2 1 
ATOM   17678 N NE1 . TRP D 1 457 ? 180.971 124.388 138.243 1.00 48.59  ? 457 TRP D NE1 1 
ATOM   17679 C CE2 . TRP D 1 457 ? 181.133 125.721 138.558 1.00 46.65  ? 457 TRP D CE2 1 
ATOM   17680 C CE3 . TRP D 1 457 ? 179.813 127.398 139.698 1.00 45.69  ? 457 TRP D CE3 1 
ATOM   17681 C CZ2 . TRP D 1 457 ? 182.159 126.644 138.338 1.00 46.50  ? 457 TRP D CZ2 1 
ATOM   17682 C CZ3 . TRP D 1 457 ? 180.838 128.337 139.474 1.00 46.27  ? 457 TRP D CZ3 1 
ATOM   17683 C CH2 . TRP D 1 457 ? 182.007 127.961 138.795 1.00 46.80  ? 457 TRP D CH2 1 
ATOM   17684 N N   . ARG D 1 458 ? 175.982 123.959 137.403 1.00 38.90  ? 458 ARG D N   1 
ATOM   17685 C CA  . ARG D 1 458 ? 175.844 123.467 136.000 1.00 37.22  ? 458 ARG D CA  1 
ATOM   17686 C C   . ARG D 1 458 ? 175.014 124.447 135.165 1.00 40.39  ? 458 ARG D C   1 
ATOM   17687 O O   . ARG D 1 458 ? 175.365 124.654 133.987 1.00 48.20  ? 458 ARG D O   1 
ATOM   17688 C CB  . ARG D 1 458 ? 175.236 122.066 135.997 1.00 37.89  ? 458 ARG D CB  1 
ATOM   17689 C CG  . ARG D 1 458 ? 176.265 121.007 136.389 1.00 33.03  ? 458 ARG D CG  1 
ATOM   17690 C CD  . ARG D 1 458 ? 175.698 119.607 136.147 1.00 35.18  ? 458 ARG D CD  1 
ATOM   17691 N NE  . ARG D 1 458 ? 174.674 119.278 137.129 1.00 36.16  ? 458 ARG D NE  1 
ATOM   17692 C CZ  . ARG D 1 458 ? 173.389 119.595 137.018 1.00 40.16  ? 458 ARG D CZ  1 
ATOM   17693 N NH1 . ARG D 1 458 ? 172.538 119.250 137.968 1.00 40.88  ? 458 ARG D NH1 1 
ATOM   17694 N NH2 . ARG D 1 458 ? 172.959 120.260 135.960 1.00 40.85  ? 458 ARG D NH2 1 
ATOM   17695 N N   . ARG D 1 459 ? 173.986 125.044 135.788 1.00 39.12  ? 459 ARG D N   1 
ATOM   17696 C CA  . ARG D 1 459 ? 173.058 125.971 135.086 1.00 40.05  ? 459 ARG D CA  1 
ATOM   17697 C C   . ARG D 1 459 ? 173.420 127.442 135.381 1.00 46.58  ? 459 ARG D C   1 
ATOM   17698 O O   . ARG D 1 459 ? 172.493 128.275 135.344 1.00 50.00  ? 459 ARG D O   1 
ATOM   17699 C CB  . ARG D 1 459 ? 171.612 125.698 135.554 1.00 35.85  ? 459 ARG D CB  1 
ATOM   17700 C CG  . ARG D 1 459 ? 171.129 124.244 135.354 1.00 36.77  ? 459 ARG D CG  1 
ATOM   17701 C CD  . ARG D 1 459 ? 171.158 123.790 133.892 1.00 38.05  ? 459 ARG D CD  1 
ATOM   17702 N NE  . ARG D 1 459 ? 170.952 122.354 133.764 1.00 37.44  ? 459 ARG D NE  1 
ATOM   17703 C CZ  . ARG D 1 459 ? 171.123 121.666 132.641 1.00 43.68  ? 459 ARG D CZ  1 
ATOM   17704 N NH1 . ARG D 1 459 ? 170.912 120.361 132.626 1.00 43.29  ? 459 ARG D NH1 1 
ATOM   17705 N NH2 . ARG D 1 459 ? 171.511 122.283 131.541 1.00 41.17  ? 459 ARG D NH2 1 
ATOM   17706 N N   . ARG D 1 460 ? 174.712 127.761 135.590 1.00 52.55  ? 460 ARG D N   1 
ATOM   17707 C CA  . ARG D 1 460 ? 175.144 129.145 135.986 1.00 50.21  ? 460 ARG D CA  1 
ATOM   17708 C C   . ARG D 1 460 ? 175.064 130.132 134.812 1.00 53.20  ? 460 ARG D C   1 
ATOM   17709 O O   . ARG D 1 460 ? 174.714 131.301 135.061 1.00 53.61  ? 460 ARG D O   1 
ATOM   17710 C CB  . ARG D 1 460 ? 176.532 129.131 136.650 1.00 49.37  ? 460 ARG D CB  1 
ATOM   17711 C CG  . ARG D 1 460 ? 177.680 128.774 135.698 1.00 47.51  ? 460 ARG D CG  1 
ATOM   17712 C CD  . ARG D 1 460 ? 178.958 128.480 136.479 1.00 49.21  ? 460 ARG D CD  1 
ATOM   17713 N NE  . ARG D 1 460 ? 180.035 127.967 135.646 1.00 52.75  ? 460 ARG D NE  1 
ATOM   17714 C CZ  . ARG D 1 460 ? 180.254 126.679 135.406 1.00 54.17  ? 460 ARG D CZ  1 
ATOM   17715 N NH1 . ARG D 1 460 ? 181.263 126.311 134.635 1.00 51.21  ? 460 ARG D NH1 1 
ATOM   17716 N NH2 . ARG D 1 460 ? 179.464 125.763 135.938 1.00 54.53  ? 460 ARG D NH2 1 
ATOM   17717 N N   . LEU D 1 461 ? 175.364 129.686 133.595 1.00 52.83  ? 461 LEU D N   1 
ATOM   17718 C CA  . LEU D 1 461 ? 175.363 130.534 132.391 1.00 52.06  ? 461 LEU D CA  1 
ATOM   17719 C C   . LEU D 1 461 ? 173.961 131.046 132.013 1.00 52.62  ? 461 LEU D C   1 
ATOM   17720 O O   . LEU D 1 461 ? 173.833 132.052 131.320 1.00 54.38  ? 461 LEU D O   1 
ATOM   17721 C CB  . LEU D 1 461 ? 175.989 129.765 131.212 1.00 55.68  ? 461 LEU D CB  1 
ATOM   17722 C CG  . LEU D 1 461 ? 177.437 129.280 131.420 1.00 56.25  ? 461 LEU D CG  1 
ATOM   17723 C CD1 . LEU D 1 461 ? 177.894 128.480 130.208 1.00 51.91  ? 461 LEU D CD1 1 
ATOM   17724 C CD2 . LEU D 1 461 ? 178.409 130.433 131.617 1.00 53.10  ? 461 LEU D CD2 1 
ATOM   17725 N N   . PHE D 1 462 ? 172.912 130.373 132.493 1.00 50.24  ? 462 PHE D N   1 
ATOM   17726 C CA  . PHE D 1 462 ? 171.500 130.684 132.244 1.00 51.06  ? 462 PHE D CA  1 
ATOM   17727 C C   . PHE D 1 462 ? 170.704 130.736 133.558 1.00 49.29  ? 462 PHE D C   1 
ATOM   17728 O O   . PHE D 1 462 ? 169.524 130.384 133.619 1.00 51.17  ? 462 PHE D O   1 
ATOM   17729 C CB  . PHE D 1 462 ? 170.927 129.687 131.219 1.00 49.11  ? 462 PHE D CB  1 
ATOM   17730 C CG  . PHE D 1 462 ? 171.568 129.793 129.851 1.00 46.83  ? 462 PHE D CG  1 
ATOM   17731 C CD1 . PHE D 1 462 ? 171.068 130.709 128.911 1.00 47.83  ? 462 PHE D CD1 1 
ATOM   17732 C CD2 . PHE D 1 462 ? 172.686 129.003 129.527 1.00 48.81  ? 462 PHE D CD2 1 
ATOM   17733 C CE1 . PHE D 1 462 ? 171.688 130.846 127.656 1.00 49.97  ? 462 PHE D CE1 1 
ATOM   17734 C CE2 . PHE D 1 462 ? 173.309 129.143 128.276 1.00 52.02  ? 462 PHE D CE2 1 
ATOM   17735 C CZ  . PHE D 1 462 ? 172.810 130.060 127.341 1.00 49.41  ? 462 PHE D CZ  1 
ATOM   17736 N N   . ILE D 1 463 ? 171.348 131.145 134.653 1.00 51.99  ? 463 ILE D N   1 
ATOM   17737 C CA  . ILE D 1 463 ? 170.803 130.939 135.996 1.00 56.47  ? 463 ILE D CA  1 
ATOM   17738 C C   . ILE D 1 463 ? 169.461 131.650 136.210 1.00 54.74  ? 463 ILE D C   1 
ATOM   17739 O O   . ILE D 1 463 ? 168.539 131.025 136.723 1.00 54.98  ? 463 ILE D O   1 
ATOM   17740 C CB  . ILE D 1 463 ? 171.860 131.266 137.069 1.00 54.84  ? 463 ILE D CB  1 
ATOM   17741 C CG1 . ILE D 1 463 ? 171.414 130.699 138.430 1.00 53.67  ? 463 ILE D CG1 1 
ATOM   17742 C CG2 . ILE D 1 463 ? 172.190 132.762 137.168 1.00 54.74  ? 463 ILE D CG2 1 
ATOM   17743 C CD1 . ILE D 1 463 ? 172.547 130.582 139.452 1.00 54.57  ? 463 ILE D CD1 1 
ATOM   17744 N N   . TRP D 1 464 ? 169.298 132.880 135.717 1.00 60.40  ? 464 TRP D N   1 
ATOM   17745 C CA  . TRP D 1 464 ? 168.066 133.670 135.836 1.00 58.36  ? 464 TRP D CA  1 
ATOM   17746 C C   . TRP D 1 464 ? 166.836 133.061 135.142 1.00 60.81  ? 464 TRP D C   1 
ATOM   17747 O O   . TRP D 1 464 ? 165.710 133.473 135.417 1.00 61.27  ? 464 TRP D O   1 
ATOM   17748 C CB  . TRP D 1 464 ? 168.332 135.060 135.268 1.00 55.43  ? 464 TRP D CB  1 
ATOM   17749 N N   . ILE D 1 465 ? 167.037 132.072 134.266 1.00 62.50  ? 465 ILE D N   1 
ATOM   17750 C CA  . ILE D 1 465 ? 165.969 131.267 133.657 1.00 61.57  ? 465 ILE D CA  1 
ATOM   17751 C C   . ILE D 1 465 ? 165.960 129.803 134.136 1.00 59.78  ? 465 ILE D C   1 
ATOM   17752 O O   . ILE D 1 465 ? 164.925 129.151 134.086 1.00 60.51  ? 465 ILE D O   1 
ATOM   17753 C CB  . ILE D 1 465 ? 165.971 131.426 132.119 1.00 60.68  ? 465 ILE D CB  1 
ATOM   17754 C CG1 . ILE D 1 465 ? 167.229 130.876 131.431 1.00 58.73  ? 465 ILE D CG1 1 
ATOM   17755 C CG2 . ILE D 1 465 ? 165.707 132.898 131.762 1.00 59.27  ? 465 ILE D CG2 1 
ATOM   17756 C CD1 . ILE D 1 465 ? 167.125 130.862 129.908 1.00 49.76  ? 465 ILE D CD1 1 
ATOM   17757 N N   . SER D 1 466 ? 167.050 129.292 134.719 1.00 57.90  ? 466 SER D N   1 
ATOM   17758 C CA  . SER D 1 466 ? 167.155 127.926 135.270 1.00 60.94  ? 466 SER D CA  1 
ATOM   17759 C C   . SER D 1 466 ? 166.155 127.582 136.394 1.00 61.67  ? 466 SER D C   1 
ATOM   17760 O O   . SER D 1 466 ? 165.998 126.405 136.738 1.00 58.77  ? 466 SER D O   1 
ATOM   17761 C CB  . SER D 1 466 ? 168.566 127.697 135.808 1.00 59.24  ? 466 SER D CB  1 
ATOM   17762 O OG  . SER D 1 466 ? 168.755 128.355 137.046 1.00 59.01  ? 466 SER D OG  1 
ATOM   17763 N N   . PHE D 1 467 ? 165.492 128.592 136.964 1.00 64.14  ? 467 PHE D N   1 
ATOM   17764 C CA  . PHE D 1 467 ? 164.471 128.478 138.008 1.00 63.38  ? 467 PHE D CA  1 
ATOM   17765 C C   . PHE D 1 467 ? 163.098 129.065 137.607 1.00 64.85  ? 467 PHE D C   1 
ATOM   17766 O O   . PHE D 1 467 ? 162.193 129.096 138.437 1.00 66.48  ? 467 PHE D O   1 
ATOM   17767 C CB  . PHE D 1 467 ? 165.012 129.084 139.307 1.00 61.77  ? 467 PHE D CB  1 
ATOM   17768 C CG  . PHE D 1 467 ? 165.413 130.544 139.244 1.00 63.94  ? 467 PHE D CG  1 
ATOM   17769 C CD1 . PHE D 1 467 ? 164.433 131.553 139.245 1.00 65.46  ? 467 PHE D CD1 1 
ATOM   17770 C CD2 . PHE D 1 467 ? 166.772 130.903 139.275 1.00 61.80  ? 467 PHE D CD2 1 
ATOM   17771 C CE1 . PHE D 1 467 ? 164.809 132.905 139.274 1.00 65.01  ? 467 PHE D CE1 1 
ATOM   17772 C CE2 . PHE D 1 467 ? 167.149 132.251 139.315 1.00 63.57  ? 467 PHE D CE2 1 
ATOM   17773 C CZ  . PHE D 1 467 ? 166.169 133.255 139.311 1.00 62.69  ? 467 PHE D CZ  1 
ATOM   17774 N N   . MET D 1 468 ? 162.905 129.569 136.381 1.00 63.70  ? 468 MET D N   1 
ATOM   17775 C CA  . MET D 1 468 ? 161.727 130.397 136.055 1.00 64.67  ? 468 MET D CA  1 
ATOM   17776 C C   . MET D 1 468 ? 160.400 129.620 136.060 1.00 67.25  ? 468 MET D C   1 
ATOM   17777 O O   . MET D 1 468 ? 159.413 130.089 136.618 1.00 65.80  ? 468 MET D O   1 
ATOM   17778 C CB  . MET D 1 468 ? 161.949 131.142 134.729 1.00 65.54  ? 468 MET D CB  1 
ATOM   17779 C CG  . MET D 1 468 ? 161.890 130.266 133.479 1.00 66.00  ? 468 MET D CG  1 
ATOM   17780 S SD  . MET D 1 468 ? 162.450 131.107 131.981 1.00 77.49  ? 468 MET D SD  1 
ATOM   17781 C CE  . MET D 1 468 ? 162.694 129.656 130.933 1.00 61.89  ? 468 MET D CE  1 
ATOM   17782 N N   . ASP D 1 469 ? 160.388 128.408 135.498 1.00 60.77  ? 469 ASP D N   1 
ATOM   17783 C CA  . ASP D 1 469 ? 159.285 127.433 135.577 1.00 58.04  ? 469 ASP D CA  1 
ATOM   17784 C C   . ASP D 1 469 ? 159.636 126.255 136.506 1.00 52.71  ? 469 ASP D C   1 
ATOM   17785 O O   . ASP D 1 469 ? 158.897 125.274 136.606 1.00 53.60  ? 469 ASP D O   1 
ATOM   17786 C CB  . ASP D 1 469 ? 158.879 126.969 134.167 1.00 57.92  ? 469 ASP D CB  1 
ATOM   17787 C CG  . ASP D 1 469 ? 159.984 126.276 133.362 1.00 56.12  ? 469 ASP D CG  1 
ATOM   17788 O OD1 . ASP D 1 469 ? 161.125 126.148 133.847 1.00 57.25  ? 469 ASP D OD1 1 
ATOM   17789 O OD2 . ASP D 1 469 ? 159.709 125.890 132.209 1.00 59.63  ? 469 ASP D OD2 1 
ATOM   17790 N N   . SER D 1 470 ? 160.738 126.391 137.238 1.00 49.46  ? 470 SER D N   1 
ATOM   17791 C CA  . SER D 1 470 ? 161.462 125.379 138.013 1.00 49.45  ? 470 SER D CA  1 
ATOM   17792 C C   . SER D 1 470 ? 161.922 125.942 139.368 1.00 47.94  ? 470 SER D C   1 
ATOM   17793 O O   . SER D 1 470 ? 163.029 125.692 139.839 1.00 48.78  ? 470 SER D O   1 
ATOM   17794 C CB  . SER D 1 470 ? 162.625 124.861 137.163 1.00 49.69  ? 470 SER D CB  1 
ATOM   17795 O OG  . SER D 1 470 ? 163.343 125.965 136.661 1.00 54.89  ? 470 SER D OG  1 
ATOM   17796 N N   . TYR D 1 471 ? 161.049 126.714 140.024 1.00 39.18  ? 471 TYR D N   1 
ATOM   17797 C CA  . TYR D 1 471 ? 161.293 127.290 141.348 1.00 36.55  ? 471 TYR D CA  1 
ATOM   17798 C C   . TYR D 1 471 ? 161.490 126.235 142.442 1.00 32.12  ? 471 TYR D C   1 
ATOM   17799 O O   . TYR D 1 471 ? 162.021 126.551 143.497 1.00 37.34  ? 471 TYR D O   1 
ATOM   17800 C CB  . TYR D 1 471 ? 160.153 128.257 141.713 1.00 42.33  ? 471 TYR D CB  1 
ATOM   17801 C CG  . TYR D 1 471 ? 158.791 127.619 141.915 1.00 41.07  ? 471 TYR D CG  1 
ATOM   17802 C CD1 . TYR D 1 471 ? 158.593 126.710 142.971 1.00 40.91  ? 471 TYR D CD1 1 
ATOM   17803 C CD2 . TYR D 1 471 ? 157.710 127.950 141.081 1.00 44.05  ? 471 TYR D CD2 1 
ATOM   17804 C CE1 . TYR D 1 471 ? 157.376 126.043 143.130 1.00 39.87  ? 471 TYR D CE1 1 
ATOM   17805 C CE2 . TYR D 1 471 ? 156.454 127.344 141.292 1.00 46.66  ? 471 TYR D CE2 1 
ATOM   17806 C CZ  . TYR D 1 471 ? 156.297 126.361 142.295 1.00 45.92  ? 471 TYR D CZ  1 
ATOM   17807 O OH  . TYR D 1 471 ? 155.102 125.778 142.520 1.00 41.70  ? 471 TYR D OH  1 
ATOM   17808 N N   . PHE D 1 472 ? 161.106 124.973 142.230 1.00 29.54  ? 472 PHE D N   1 
ATOM   17809 C CA  . PHE D 1 472 ? 161.436 123.890 143.150 1.00 18.15  ? 472 PHE D CA  1 
ATOM   17810 C C   . PHE D 1 472 ? 162.939 123.713 143.319 1.00 18.77  ? 472 PHE D C   1 
ATOM   17811 O O   . PHE D 1 472 ? 163.362 123.278 144.376 1.00 37.88  ? 472 PHE D O   1 
ATOM   17812 C CB  . PHE D 1 472 ? 160.787 122.573 142.712 1.00 23.48  ? 472 PHE D CB  1 
ATOM   17813 C CG  . PHE D 1 472 ? 159.373 122.396 143.207 1.00 17.85  ? 472 PHE D CG  1 
ATOM   17814 C CD1 . PHE D 1 472 ? 159.139 122.302 144.588 1.00 20.34  ? 472 PHE D CD1 1 
ATOM   17815 C CD2 . PHE D 1 472 ? 158.301 122.294 142.307 1.00 21.46  ? 472 PHE D CD2 1 
ATOM   17816 C CE1 . PHE D 1 472 ? 157.836 122.133 145.070 1.00 17.43  ? 472 PHE D CE1 1 
ATOM   17817 C CE2 . PHE D 1 472 ? 157.000 122.094 142.792 1.00 19.70  ? 472 PHE D CE2 1 
ATOM   17818 C CZ  . PHE D 1 472 ? 156.773 122.015 144.173 1.00 22.00  ? 472 PHE D CZ  1 
ATOM   17819 N N   . GLU D 1 473 ? 163.778 124.104 142.367 1.00 28.40  ? 473 GLU D N   1 
ATOM   17820 C CA  . GLU D 1 473 ? 165.227 124.104 142.582 1.00 28.14  ? 473 GLU D CA  1 
ATOM   17821 C C   . GLU D 1 473 ? 165.650 125.180 143.603 1.00 29.94  ? 473 GLU D C   1 
ATOM   17822 O O   . GLU D 1 473 ? 166.536 124.969 144.421 1.00 34.40  ? 473 GLU D O   1 
ATOM   17823 C CB  . GLU D 1 473 ? 165.960 124.254 141.238 1.00 30.66  ? 473 GLU D CB  1 
ATOM   17824 C CG  . GLU D 1 473 ? 165.555 123.208 140.181 1.00 27.04  ? 473 GLU D CG  1 
ATOM   17825 C CD  . GLU D 1 473 ? 165.759 121.746 140.613 1.00 38.11  ? 473 GLU D CD  1 
ATOM   17826 O OE1 . GLU D 1 473 ? 166.860 121.360 141.051 1.00 39.24  ? 473 GLU D OE1 1 
ATOM   17827 O OE2 . GLU D 1 473 ? 164.786 120.958 140.521 1.00 47.14  ? 473 GLU D OE2 1 
ATOM   17828 N N   . ILE D 1 474 ? 164.965 126.324 143.658 1.00 34.79  ? 474 ILE D N   1 
ATOM   17829 C CA  . ILE D 1 474 ? 165.135 127.293 144.749 1.00 25.72  ? 474 ILE D CA  1 
ATOM   17830 C C   . ILE D 1 474 ? 164.579 126.731 146.066 1.00 27.11  ? 474 ILE D C   1 
ATOM   17831 O O   . ILE D 1 474 ? 165.249 126.814 147.088 1.00 37.13  ? 474 ILE D O   1 
ATOM   17832 C CB  . ILE D 1 474 ? 164.523 128.668 144.383 1.00 32.78  ? 474 ILE D CB  1 
ATOM   17833 C CG1 . ILE D 1 474 ? 165.338 129.293 143.235 1.00 32.02  ? 474 ILE D CG1 1 
ATOM   17834 C CG2 . ILE D 1 474 ? 164.488 129.609 145.601 1.00 28.37  ? 474 ILE D CG2 1 
ATOM   17835 C CD1 . ILE D 1 474 ? 164.807 130.627 142.712 1.00 36.89  ? 474 ILE D CD1 1 
ATOM   17836 N N   . LEU D 1 475 ? 163.381 126.140 146.075 1.00 25.68  ? 475 LEU D N   1 
ATOM   17837 C CA  . LEU D 1 475 ? 162.755 125.644 147.303 1.00 17.93  ? 475 LEU D CA  1 
ATOM   17838 C C   . LEU D 1 475 ? 163.473 124.433 147.915 1.00 19.70  ? 475 LEU D C   1 
ATOM   17839 O O   . LEU D 1 475 ? 163.574 124.346 149.136 1.00 30.74  ? 475 LEU D O   1 
ATOM   17840 C CB  . LEU D 1 475 ? 161.274 125.322 147.074 1.00 28.40  ? 475 LEU D CB  1 
ATOM   17841 C CG  . LEU D 1 475 ? 160.392 126.484 146.590 1.00 26.69  ? 475 LEU D CG  1 
ATOM   17842 C CD1 . LEU D 1 475 ? 158.977 125.973 146.366 1.00 29.50  ? 475 LEU D CD1 1 
ATOM   17843 C CD2 . LEU D 1 475 ? 160.332 127.658 147.557 1.00 17.91  ? 475 LEU D CD2 1 
ATOM   17844 N N   . PHE D 1 476 ? 164.016 123.513 147.116 1.00 13.50  ? 476 PHE D N   1 
ATOM   17845 C CA  . PHE D 1 476 ? 164.864 122.425 147.606 1.00 9.69   ? 476 PHE D CA  1 
ATOM   17846 C C   . PHE D 1 476 ? 166.202 122.940 148.146 1.00 11.47  ? 476 PHE D C   1 
ATOM   17847 O O   . PHE D 1 476 ? 166.636 122.467 149.191 1.00 22.61  ? 476 PHE D O   1 
ATOM   17848 C CB  . PHE D 1 476 ? 165.071 121.362 146.522 1.00 13.93  ? 476 PHE D CB  1 
ATOM   17849 C CG  . PHE D 1 476 ? 164.017 120.268 146.473 1.00 11.99  ? 476 PHE D CG  1 
ATOM   17850 C CD1 . PHE D 1 476 ? 162.762 120.487 145.883 1.00 13.79  ? 476 PHE D CD1 1 
ATOM   17851 C CD2 . PHE D 1 476 ? 164.309 119.000 147.003 1.00 9.56   ? 476 PHE D CD2 1 
ATOM   17852 C CE1 . PHE D 1 476 ? 161.830 119.446 145.780 1.00 10.13  ? 476 PHE D CE1 1 
ATOM   17853 C CE2 . PHE D 1 476 ? 163.374 117.961 146.910 1.00 13.54  ? 476 PHE D CE2 1 
ATOM   17854 C CZ  . PHE D 1 476 ? 162.138 118.180 146.289 1.00 9.53   ? 476 PHE D CZ  1 
ATOM   17855 N N   . LEU D 1 477 ? 166.828 123.940 147.511 1.00 24.46  ? 477 LEU D N   1 
ATOM   17856 C CA  . LEU D 1 477 ? 168.027 124.588 148.043 1.00 27.82  ? 477 LEU D CA  1 
ATOM   17857 C C   . LEU D 1 477 ? 167.758 125.284 149.382 1.00 22.59  ? 477 LEU D C   1 
ATOM   17858 O O   . LEU D 1 477 ? 168.498 125.085 150.341 1.00 31.90  ? 477 LEU D O   1 
ATOM   17859 C CB  . LEU D 1 477 ? 168.586 125.586 147.007 1.00 27.64  ? 477 LEU D CB  1 
ATOM   17860 C CG  . LEU D 1 477 ? 169.863 126.313 147.462 1.00 29.88  ? 477 LEU D CG  1 
ATOM   17861 C CD1 . LEU D 1 477 ? 171.063 125.384 147.503 1.00 27.58  ? 477 LEU D CD1 1 
ATOM   17862 C CD2 . LEU D 1 477 ? 170.183 127.463 146.522 1.00 29.74  ? 477 LEU D CD2 1 
ATOM   17863 N N   . LEU D 1 478 ? 166.683 126.070 149.469 1.00 25.68  ? 478 LEU D N   1 
ATOM   17864 C CA  . LEU D 1 478 ? 166.289 126.767 150.687 1.00 20.98  ? 478 LEU D CA  1 
ATOM   17865 C C   . LEU D 1 478 ? 165.976 125.794 151.828 1.00 18.21  ? 478 LEU D C   1 
ATOM   17866 O O   . LEU D 1 478 ? 166.437 126.002 152.945 1.00 31.35  ? 478 LEU D O   1 
ATOM   17867 C CB  . LEU D 1 478 ? 165.124 127.709 150.363 1.00 28.45  ? 478 LEU D CB  1 
ATOM   17868 C CG  . LEU D 1 478 ? 164.606 128.518 151.559 1.00 36.43  ? 478 LEU D CG  1 
ATOM   17869 C CD1 . LEU D 1 478 ? 165.654 129.469 152.118 1.00 27.98  ? 478 LEU D CD1 1 
ATOM   17870 C CD2 . LEU D 1 478 ? 163.378 129.314 151.142 1.00 27.32  ? 478 LEU D CD2 1 
ATOM   17871 N N   . GLN D 1 479 ? 165.268 124.693 151.572 1.00 17.57  ? 479 GLN D N   1 
ATOM   17872 C CA  . GLN D 1 479 ? 164.996 123.676 152.588 1.00 17.28  ? 479 GLN D CA  1 
ATOM   17873 C C   . GLN D 1 479 ? 166.272 123.042 153.133 1.00 20.46  ? 479 GLN D C   1 
ATOM   17874 O O   . GLN D 1 479 ? 166.413 122.875 154.340 1.00 28.93  ? 479 GLN D O   1 
ATOM   17875 C CB  . GLN D 1 479 ? 164.071 122.607 151.996 1.00 19.84  ? 479 GLN D CB  1 
ATOM   17876 C CG  . GLN D 1 479 ? 163.322 121.781 153.048 1.00 19.43  ? 479 GLN D CG  1 
ATOM   17877 C CD  . GLN D 1 479 ? 164.007 120.535 153.608 1.00 21.70  ? 479 GLN D CD  1 
ATOM   17878 O OE1 . GLN D 1 479 ? 164.952 119.980 153.074 1.00 23.79  ? 479 GLN D OE1 1 
ATOM   17879 N NE2 . GLN D 1 479 ? 163.498 120.015 154.696 1.00 30.31  ? 479 GLN D NE2 1 
ATOM   17880 N N   . ALA D 1 480 ? 167.229 122.730 152.263 1.00 28.61  ? 480 ALA D N   1 
ATOM   17881 C CA  . ALA D 1 480 ? 168.509 122.166 152.638 1.00 24.18  ? 480 ALA D CA  1 
ATOM   17882 C C   . ALA D 1 480 ? 169.372 123.155 153.442 1.00 24.10  ? 480 ALA D C   1 
ATOM   17883 O O   . ALA D 1 480 ? 169.927 122.780 154.470 1.00 27.06  ? 480 ALA D O   1 
ATOM   17884 C CB  . ALA D 1 480 ? 169.186 121.705 151.358 1.00 29.88  ? 480 ALA D CB  1 
ATOM   17885 N N   . LEU D 1 481 ? 169.426 124.435 153.050 1.00 24.01  ? 481 LEU D N   1 
ATOM   17886 C CA  . LEU D 1 481 ? 170.078 125.495 153.825 1.00 28.63  ? 481 LEU D CA  1 
ATOM   17887 C C   . LEU D 1 481 ? 169.473 125.645 155.225 1.00 29.78  ? 481 LEU D C   1 
ATOM   17888 O O   . LEU D 1 481 ? 170.198 125.564 156.212 1.00 33.93  ? 481 LEU D O   1 
ATOM   17889 C CB  . LEU D 1 481 ? 169.984 126.839 153.081 1.00 31.27  ? 481 LEU D CB  1 
ATOM   17890 C CG  . LEU D 1 481 ? 170.962 127.000 151.911 1.00 35.54  ? 481 LEU D CG  1 
ATOM   17891 C CD1 . LEU D 1 481 ? 170.629 128.274 151.141 1.00 35.61  ? 481 LEU D CD1 1 
ATOM   17892 C CD2 . LEU D 1 481 ? 172.405 127.110 152.399 1.00 31.02  ? 481 LEU D CD2 1 
ATOM   17893 N N   . LEU D 1 482 ? 168.155 125.824 155.327 1.00 33.85  ? 482 LEU D N   1 
ATOM   17894 C CA  . LEU D 1 482 ? 167.467 125.971 156.611 1.00 26.18  ? 482 LEU D CA  1 
ATOM   17895 C C   . LEU D 1 482 ? 167.621 124.722 157.486 1.00 19.12  ? 482 LEU D C   1 
ATOM   17896 O O   . LEU D 1 482 ? 167.762 124.838 158.700 1.00 32.65  ? 482 LEU D O   1 
ATOM   17897 C CB  . LEU D 1 482 ? 165.990 126.303 156.373 1.00 30.20  ? 482 LEU D CB  1 
ATOM   17898 C CG  . LEU D 1 482 ? 165.711 127.644 155.684 1.00 30.29  ? 482 LEU D CG  1 
ATOM   17899 C CD1 . LEU D 1 482 ? 164.224 127.721 155.357 1.00 28.26  ? 482 LEU D CD1 1 
ATOM   17900 C CD2 . LEU D 1 482 ? 166.072 128.837 156.555 1.00 29.62  ? 482 LEU D CD2 1 
ATOM   17901 N N   . THR D 1 483 ? 167.696 123.535 156.884 1.00 25.03  ? 483 THR D N   1 
ATOM   17902 C CA  . THR D 1 483 ? 167.991 122.295 157.600 1.00 25.83  ? 483 THR D CA  1 
ATOM   17903 C C   . THR D 1 483 ? 169.390 122.311 158.196 1.00 30.04  ? 483 THR D C   1 
ATOM   17904 O O   . THR D 1 483 ? 169.528 122.104 159.395 1.00 40.80  ? 483 THR D O   1 
ATOM   17905 C CB  . THR D 1 483 ? 167.833 121.072 156.698 1.00 27.38  ? 483 THR D CB  1 
ATOM   17906 O OG1 . THR D 1 483 ? 166.523 121.025 156.220 1.00 38.10  ? 483 THR D OG1 1 
ATOM   17907 C CG2 . THR D 1 483 ? 168.086 119.774 157.449 1.00 29.80  ? 483 THR D CG2 1 
ATOM   17908 N N   . VAL D 1 484 ? 170.428 122.603 157.411 1.00 40.82  ? 484 VAL D N   1 
ATOM   17909 C CA  . VAL D 1 484 ? 171.809 122.667 157.901 1.00 37.48  ? 484 VAL D CA  1 
ATOM   17910 C C   . VAL D 1 484 ? 171.966 123.770 158.947 1.00 37.25  ? 484 VAL D C   1 
ATOM   17911 O O   . VAL D 1 484 ? 172.488 123.506 160.025 1.00 46.32  ? 484 VAL D O   1 
ATOM   17912 C CB  . VAL D 1 484 ? 172.796 122.810 156.725 1.00 37.10  ? 484 VAL D CB  1 
ATOM   17913 C CG1 . VAL D 1 484 ? 174.237 123.024 157.186 1.00 39.12  ? 484 VAL D CG1 1 
ATOM   17914 C CG2 . VAL D 1 484 ? 172.780 121.540 155.876 1.00 37.14  ? 484 VAL D CG2 1 
ATOM   17915 N N   . LEU D 1 485 ? 171.421 124.963 158.712 1.00 38.90  ? 485 LEU D N   1 
ATOM   17916 C CA  . LEU D 1 485 ? 171.414 126.042 159.698 1.00 39.37  ? 485 LEU D CA  1 
ATOM   17917 C C   . LEU D 1 485 ? 170.709 125.634 160.995 1.00 41.24  ? 485 LEU D C   1 
ATOM   17918 O O   . LEU D 1 485 ? 171.246 125.884 162.065 1.00 44.83  ? 485 LEU D O   1 
ATOM   17919 C CB  . LEU D 1 485 ? 170.784 127.308 159.102 1.00 37.67  ? 485 LEU D CB  1 
ATOM   17920 C CG  . LEU D 1 485 ? 171.659 127.991 158.043 1.00 48.38  ? 485 LEU D CG  1 
ATOM   17921 C CD1 . LEU D 1 485 ? 170.840 129.039 157.296 1.00 45.48  ? 485 LEU D CD1 1 
ATOM   17922 C CD2 . LEU D 1 485 ? 172.874 128.670 158.672 1.00 46.90  ? 485 LEU D CD2 1 
ATOM   17923 N N   . SER D 1 486 ? 169.567 124.947 160.943 1.00 40.41  ? 486 SER D N   1 
ATOM   17924 C CA  . SER D 1 486 ? 168.896 124.471 162.160 1.00 34.06  ? 486 SER D CA  1 
ATOM   17925 C C   . SER D 1 486 ? 169.771 123.514 162.972 1.00 40.08  ? 486 SER D C   1 
ATOM   17926 O O   . SER D 1 486 ? 169.789 123.600 164.192 1.00 47.40  ? 486 SER D O   1 
ATOM   17927 C CB  . SER D 1 486 ? 167.545 123.830 161.843 1.00 34.81  ? 486 SER D CB  1 
ATOM   17928 O OG  . SER D 1 486 ? 167.677 122.544 161.287 1.00 41.13  ? 486 SER D OG  1 
ATOM   17929 N N   . GLN D 1 487 ? 170.563 122.652 162.332 1.00 45.19  ? 487 GLN D N   1 
ATOM   17930 C CA  . GLN D 1 487 ? 171.486 121.754 163.029 1.00 44.12  ? 487 GLN D CA  1 
ATOM   17931 C C   . GLN D 1 487 ? 172.711 122.484 163.593 1.00 44.29  ? 487 GLN D C   1 
ATOM   17932 O O   . GLN D 1 487 ? 173.135 122.187 164.705 1.00 47.22  ? 487 GLN D O   1 
ATOM   17933 C CB  . GLN D 1 487 ? 171.906 120.614 162.097 1.00 44.22  ? 487 GLN D CB  1 
ATOM   17934 C CG  . GLN D 1 487 ? 170.721 119.762 161.626 1.00 43.31  ? 487 GLN D CG  1 
ATOM   17935 C CD  . GLN D 1 487 ? 169.861 119.248 162.769 1.00 45.13  ? 487 GLN D CD  1 
ATOM   17936 O OE1 . GLN D 1 487 ? 170.339 118.646 163.716 1.00 51.78  ? 487 GLN D OE1 1 
ATOM   17937 N NE2 . GLN D 1 487 ? 168.568 119.481 162.741 1.00 45.83  ? 487 GLN D NE2 1 
ATOM   17938 N N   . VAL D 1 488 ? 173.229 123.501 162.898 1.00 48.48  ? 488 VAL D N   1 
ATOM   17939 C CA  . VAL D 1 488 ? 174.274 124.393 163.424 1.00 49.13  ? 488 VAL D CA  1 
ATOM   17940 C C   . VAL D 1 488 ? 173.778 125.156 164.656 1.00 51.61  ? 488 VAL D C   1 
ATOM   17941 O O   . VAL D 1 488 ? 174.431 125.133 165.696 1.00 53.86  ? 488 VAL D O   1 
ATOM   17942 C CB  . VAL D 1 488 ? 174.763 125.355 162.323 1.00 48.60  ? 488 VAL D CB  1 
ATOM   17943 C CG1 . VAL D 1 488 ? 175.707 126.435 162.852 1.00 50.61  ? 488 VAL D CG1 1 
ATOM   17944 C CG2 . VAL D 1 488 ? 175.509 124.583 161.231 1.00 45.73  ? 488 VAL D CG2 1 
ATOM   17945 N N   . LEU D 1 489 ? 172.592 125.768 164.598 1.00 49.63  ? 489 LEU D N   1 
ATOM   17946 C CA  . LEU D 1 489 ? 172.002 126.459 165.747 1.00 44.98  ? 489 LEU D CA  1 
ATOM   17947 C C   . LEU D 1 489 ? 171.702 125.502 166.909 1.00 44.76  ? 489 LEU D C   1 
ATOM   17948 O O   . LEU D 1 489 ? 171.876 125.877 168.066 1.00 53.42  ? 489 LEU D O   1 
ATOM   17949 C CB  . LEU D 1 489 ? 170.728 127.209 165.324 1.00 48.57  ? 489 LEU D CB  1 
ATOM   17950 C CG  . LEU D 1 489 ? 170.895 128.387 164.350 1.00 47.46  ? 489 LEU D CG  1 
ATOM   17951 C CD1 . LEU D 1 489 ? 169.663 129.283 164.457 1.00 45.55  ? 489 LEU D CD1 1 
ATOM   17952 C CD2 . LEU D 1 489 ? 172.122 129.257 164.617 1.00 47.28  ? 489 LEU D CD2 1 
ATOM   17953 N N   . ARG D 1 490 ? 171.308 124.257 166.629 1.00 42.08  ? 490 ARG D N   1 
ATOM   17954 C CA  . ARG D 1 490 ? 171.113 123.216 167.645 1.00 47.42  ? 490 ARG D CA  1 
ATOM   17955 C C   . ARG D 1 490 ? 172.424 122.838 168.340 1.00 52.44  ? 490 ARG D C   1 
ATOM   17956 O O   . ARG D 1 490 ? 172.436 122.703 169.559 1.00 58.06  ? 490 ARG D O   1 
ATOM   17957 C CB  . ARG D 1 490 ? 170.439 122.011 166.984 1.00 49.96  ? 490 ARG D CB  1 
ATOM   17958 C CG  . ARG D 1 490 ? 170.047 120.940 167.995 1.00 44.81  ? 490 ARG D CG  1 
ATOM   17959 C CD  . ARG D 1 490 ? 169.487 119.719 167.272 1.00 50.55  ? 490 ARG D CD  1 
ATOM   17960 N NE  . ARG D 1 490 ? 169.380 118.571 168.187 1.00 57.82  ? 490 ARG D NE  1 
ATOM   17961 C CZ  . ARG D 1 490 ? 170.338 117.738 168.543 1.00 54.27  ? 490 ARG D CZ  1 
ATOM   17962 N NH1 . ARG D 1 490 ? 170.110 116.804 169.412 1.00 53.12  ? 490 ARG D NH1 1 
ATOM   17963 N NH2 . ARG D 1 490 ? 171.538 117.817 168.066 1.00 49.85  ? 490 ARG D NH2 1 
ATOM   17964 N N   . PHE D 1 491 ? 173.540 122.726 167.614 1.00 57.86  ? 491 PHE D N   1 
ATOM   17965 C CA  . PHE D 1 491 ? 174.867 122.532 168.225 1.00 57.35  ? 491 PHE D CA  1 
ATOM   17966 C C   . PHE D 1 491 ? 175.328 123.747 169.054 1.00 60.68  ? 491 PHE D C   1 
ATOM   17967 O O   . PHE D 1 491 ? 175.937 123.570 170.107 1.00 62.21  ? 491 PHE D O   1 
ATOM   17968 C CB  . PHE D 1 491 ? 175.906 122.199 167.146 1.00 56.81  ? 491 PHE D CB  1 
ATOM   17969 C CG  . PHE D 1 491 ? 175.679 120.936 166.330 1.00 60.54  ? 491 PHE D CG  1 
ATOM   17970 C CD1 . PHE D 1 491 ? 175.088 119.788 166.893 1.00 60.16  ? 491 PHE D CD1 1 
ATOM   17971 C CD2 . PHE D 1 491 ? 176.126 120.892 164.992 1.00 60.86  ? 491 PHE D CD2 1 
ATOM   17972 C CE1 . PHE D 1 491 ? 174.937 118.620 166.127 1.00 58.92  ? 491 PHE D CE1 1 
ATOM   17973 C CE2 . PHE D 1 491 ? 175.968 119.725 164.226 1.00 60.13  ? 491 PHE D CE2 1 
ATOM   17974 C CZ  . PHE D 1 491 ? 175.378 118.585 164.795 1.00 60.90  ? 491 PHE D CZ  1 
ATOM   17975 N N   . MET D 1 492 ? 174.989 124.971 168.643 1.00 59.42  ? 492 MET D N   1 
ATOM   17976 C CA  . MET D 1 492 ? 175.172 126.190 169.450 1.00 58.85  ? 492 MET D CA  1 
ATOM   17977 C C   . MET D 1 492 ? 174.205 126.308 170.645 1.00 60.65  ? 492 MET D C   1 
ATOM   17978 O O   . MET D 1 492 ? 174.334 127.231 171.446 1.00 63.29  ? 492 MET D O   1 
ATOM   17979 C CB  . MET D 1 492 ? 175.037 127.431 168.557 1.00 59.12  ? 492 MET D CB  1 
ATOM   17980 C CG  . MET D 1 492 ? 176.135 127.535 167.501 1.00 61.62  ? 492 MET D CG  1 
ATOM   17981 S SD  . MET D 1 492 ? 175.935 128.987 166.441 1.00 73.56  ? 492 MET D SD  1 
ATOM   17982 C CE  . MET D 1 492 ? 177.402 128.791 165.407 1.00 60.99  ? 492 MET D CE  1 
ATOM   17983 N N   . GLU D 1 493 ? 173.244 125.393 170.781 1.00 60.82  ? 493 GLU D N   1 
ATOM   17984 C CA  . GLU D 1 493 ? 172.210 125.375 171.818 1.00 61.95  ? 493 GLU D CA  1 
ATOM   17985 C C   . GLU D 1 493 ? 171.311 126.627 171.902 1.00 61.67  ? 493 GLU D C   1 
ATOM   17986 O O   . GLU D 1 493 ? 170.699 126.870 172.942 1.00 62.54  ? 493 GLU D O   1 
ATOM   17987 C CB  . GLU D 1 493 ? 172.850 125.012 173.157 1.00 59.14  ? 493 GLU D CB  1 
ATOM   17988 N N   . THR D 1 494 ? 171.202 127.434 170.840 1.00 56.06  ? 494 THR D N   1 
ATOM   17989 C CA  . THR D 1 494 ? 170.290 128.597 170.818 1.00 58.27  ? 494 THR D CA  1 
ATOM   17990 C C   . THR D 1 494 ? 168.846 128.175 170.543 1.00 56.70  ? 494 THR D C   1 
ATOM   17991 O O   . THR D 1 494 ? 168.608 127.260 169.759 1.00 59.02  ? 494 THR D O   1 
ATOM   17992 C CB  . THR D 1 494 ? 170.769 129.687 169.847 1.00 57.68  ? 494 THR D CB  1 
ATOM   17993 O OG1 . THR D 1 494 ? 169.964 130.834 169.975 1.00 58.53  ? 494 THR D OG1 1 
ATOM   17994 C CG2 . THR D 1 494 ? 170.722 129.308 168.372 1.00 54.73  ? 494 THR D CG2 1 
ATOM   17995 N N   . GLU D 1 495 ? 167.851 128.828 171.151 1.00 57.16  ? 495 GLU D N   1 
ATOM   17996 C CA  . GLU D 1 495 ? 166.433 128.455 171.002 1.00 56.33  ? 495 GLU D CA  1 
ATOM   17997 C C   . GLU D 1 495 ? 165.920 128.555 169.555 1.00 56.47  ? 495 GLU D C   1 
ATOM   17998 O O   . GLU D 1 495 ? 165.037 127.803 169.145 1.00 59.53  ? 495 GLU D O   1 
ATOM   17999 C CB  . GLU D 1 495 ? 165.572 129.307 171.948 1.00 57.57  ? 495 GLU D CB  1 
ATOM   18000 C CG  . GLU D 1 495 ? 165.449 130.784 171.531 1.00 58.05  ? 495 GLU D CG  1 
ATOM   18001 C CD  . GLU D 1 495 ? 164.643 131.620 172.534 1.00 60.80  ? 495 GLU D CD  1 
ATOM   18002 O OE1 . GLU D 1 495 ? 163.646 131.127 173.100 1.00 58.61  ? 495 GLU D OE1 1 
ATOM   18003 O OE2 . GLU D 1 495 ? 164.991 132.797 172.770 1.00 62.34  ? 495 GLU D OE2 1 
ATOM   18004 N N   . TRP D 1 496 ? 166.507 129.443 168.754 1.00 48.41  ? 496 TRP D N   1 
ATOM   18005 C CA  . TRP D 1 496 ? 166.106 129.716 167.376 1.00 47.81  ? 496 TRP D CA  1 
ATOM   18006 C C   . TRP D 1 496 ? 166.357 128.564 166.401 1.00 50.21  ? 496 TRP D C   1 
ATOM   18007 O O   . TRP D 1 496 ? 165.916 128.627 165.255 1.00 51.33  ? 496 TRP D O   1 
ATOM   18008 C CB  . TRP D 1 496 ? 166.755 131.028 166.923 1.00 48.86  ? 496 TRP D CB  1 
ATOM   18009 C CG  . TRP D 1 496 ? 166.257 132.181 167.729 1.00 54.42  ? 496 TRP D CG  1 
ATOM   18010 C CD1 . TRP D 1 496 ? 166.907 132.771 168.757 1.00 52.13  ? 496 TRP D CD1 1 
ATOM   18011 C CD2 . TRP D 1 496 ? 164.932 132.789 167.686 1.00 57.48  ? 496 TRP D CD2 1 
ATOM   18012 N NE1 . TRP D 1 496 ? 166.062 133.674 169.372 1.00 52.46  ? 496 TRP D NE1 1 
ATOM   18013 C CE2 . TRP D 1 496 ? 164.821 133.700 168.774 1.00 56.74  ? 496 TRP D CE2 1 
ATOM   18014 C CE3 . TRP D 1 496 ? 163.799 132.630 166.858 1.00 51.11  ? 496 TRP D CE3 1 
ATOM   18015 C CZ2 . TRP D 1 496 ? 163.635 134.389 169.052 1.00 53.74  ? 496 TRP D CZ2 1 
ATOM   18016 C CZ3 . TRP D 1 496 ? 162.602 133.317 167.126 1.00 52.30  ? 496 TRP D CZ3 1 
ATOM   18017 C CH2 . TRP D 1 496 ? 162.516 134.186 168.229 1.00 53.97  ? 496 TRP D CH2 1 
ATOM   18018 N N   . TYR D 1 497 ? 166.999 127.479 166.838 1.00 44.51  ? 497 TYR D N   1 
ATOM   18019 C CA  . TYR D 1 497 ? 167.067 126.264 166.038 1.00 41.00  ? 497 TYR D CA  1 
ATOM   18020 C C   . TYR D 1 497 ? 165.672 125.694 165.744 1.00 41.34  ? 497 TYR D C   1 
ATOM   18021 O O   . TYR D 1 497 ? 165.450 125.202 164.641 1.00 44.27  ? 497 TYR D O   1 
ATOM   18022 C CB  . TYR D 1 497 ? 167.980 125.236 166.720 1.00 40.74  ? 497 TYR D CB  1 
ATOM   18023 C CG  . TYR D 1 497 ? 167.277 124.169 167.525 1.00 38.88  ? 497 TYR D CG  1 
ATOM   18024 C CD1 . TYR D 1 497 ? 166.834 122.985 166.902 1.00 40.78  ? 497 TYR D CD1 1 
ATOM   18025 C CD2 . TYR D 1 497 ? 167.021 124.383 168.885 1.00 39.73  ? 497 TYR D CD2 1 
ATOM   18026 C CE1 . TYR D 1 497 ? 166.119 122.024 167.642 1.00 38.91  ? 497 TYR D CE1 1 
ATOM   18027 C CE2 . TYR D 1 497 ? 166.314 123.429 169.626 1.00 44.05  ? 497 TYR D CE2 1 
ATOM   18028 C CZ  . TYR D 1 497 ? 165.853 122.254 169.008 1.00 45.76  ? 497 TYR D CZ  1 
ATOM   18029 O OH  . TYR D 1 497 ? 165.163 121.350 169.741 1.00 48.24  ? 497 TYR D OH  1 
ATOM   18030 N N   . LEU D 1 498 ? 164.724 125.786 166.684 1.00 35.89  ? 498 LEU D N   1 
ATOM   18031 C CA  . LEU D 1 498 ? 163.421 125.137 166.555 1.00 32.29  ? 498 LEU D CA  1 
ATOM   18032 C C   . LEU D 1 498 ? 162.517 125.804 165.498 1.00 34.76  ? 498 LEU D C   1 
ATOM   18033 O O   . LEU D 1 498 ? 162.014 125.087 164.638 1.00 33.51  ? 498 LEU D O   1 
ATOM   18034 C CB  . LEU D 1 498 ? 162.778 124.950 167.943 1.00 34.90  ? 498 LEU D CB  1 
ATOM   18035 C CG  . LEU D 1 498 ? 161.458 124.164 167.913 1.00 36.78  ? 498 LEU D CG  1 
ATOM   18036 C CD1 . LEU D 1 498 ? 161.682 122.702 167.542 1.00 35.26  ? 498 LEU D CD1 1 
ATOM   18037 C CD2 . LEU D 1 498 ? 160.781 124.211 169.276 1.00 34.72  ? 498 LEU D CD2 1 
ATOM   18038 N N   . PRO D 1 499 ? 162.364 127.139 165.441 1.00 34.18  ? 499 PRO D N   1 
ATOM   18039 C CA  . PRO D 1 499 ? 161.775 127.824 164.291 1.00 30.00  ? 499 PRO D CA  1 
ATOM   18040 C C   . PRO D 1 499 ? 162.404 127.474 162.936 1.00 32.61  ? 499 PRO D C   1 
ATOM   18041 O O   . PRO D 1 499 ? 161.668 127.267 161.977 1.00 34.63  ? 499 PRO D O   1 
ATOM   18042 C CB  . PRO D 1 499 ? 161.930 129.314 164.593 1.00 31.86  ? 499 PRO D CB  1 
ATOM   18043 C CG  . PRO D 1 499 ? 161.860 129.357 166.107 1.00 28.66  ? 499 PRO D CG  1 
ATOM   18044 C CD  . PRO D 1 499 ? 162.570 128.082 166.526 1.00 26.88  ? 499 PRO D CD  1 
ATOM   18045 N N   . LEU D 1 500 ? 163.735 127.353 162.826 1.00 31.27  ? 500 LEU D N   1 
ATOM   18046 C CA  . LEU D 1 500 ? 164.380 126.943 161.571 1.00 28.70  ? 500 LEU D CA  1 
ATOM   18047 C C   . LEU D 1 500 ? 164.100 125.482 161.214 1.00 28.93  ? 500 LEU D C   1 
ATOM   18048 O O   . LEU D 1 500 ? 163.833 125.186 160.053 1.00 35.11  ? 500 LEU D O   1 
ATOM   18049 C CB  . LEU D 1 500 ? 165.901 127.164 161.611 1.00 34.27  ? 500 LEU D CB  1 
ATOM   18050 C CG  . LEU D 1 500 ? 166.394 128.612 161.695 1.00 37.55  ? 500 LEU D CG  1 
ATOM   18051 C CD1 . LEU D 1 500 ? 167.902 128.604 161.452 1.00 38.08  ? 500 LEU D CD1 1 
ATOM   18052 C CD2 . LEU D 1 500 ? 165.765 129.518 160.646 1.00 33.87  ? 500 LEU D CD2 1 
ATOM   18053 N N   . LEU D 1 501 ? 164.129 124.567 162.181 1.00 20.11  ? 501 LEU D N   1 
ATOM   18054 C CA  . LEU D 1 501 ? 163.794 123.160 161.973 1.00 22.94  ? 501 LEU D CA  1 
ATOM   18055 C C   . LEU D 1 501 ? 162.344 123.004 161.508 1.00 22.34  ? 501 LEU D C   1 
ATOM   18056 O O   . LEU D 1 501 ? 162.061 122.272 160.566 1.00 31.03  ? 501 LEU D O   1 
ATOM   18057 C CB  . LEU D 1 501 ? 164.048 122.393 163.282 1.00 23.64  ? 501 LEU D CB  1 
ATOM   18058 C CG  . LEU D 1 501 ? 163.829 120.876 163.167 1.00 24.14  ? 501 LEU D CG  1 
ATOM   18059 C CD1 . LEU D 1 501 ? 165.002 120.216 162.449 1.00 26.78  ? 501 LEU D CD1 1 
ATOM   18060 C CD2 . LEU D 1 501 ? 163.694 120.251 164.546 1.00 27.36  ? 501 LEU D CD2 1 
ATOM   18061 N N   . VAL D 1 502 ? 161.425 123.729 162.129 1.00 32.50  ? 502 VAL D N   1 
ATOM   18062 C CA  . VAL D 1 502 ? 159.999 123.728 161.800 1.00 26.40  ? 502 VAL D CA  1 
ATOM   18063 C C   . VAL D 1 502 ? 159.716 124.400 160.451 1.00 22.48  ? 502 VAL D C   1 
ATOM   18064 O O   . VAL D 1 502 ? 158.925 123.877 159.676 1.00 33.73  ? 502 VAL D O   1 
ATOM   18065 C CB  . VAL D 1 502 ? 159.217 124.342 162.975 1.00 27.86  ? 502 VAL D CB  1 
ATOM   18066 C CG1 . VAL D 1 502 ? 157.763 124.603 162.635 1.00 25.75  ? 502 VAL D CG1 1 
ATOM   18067 C CG2 . VAL D 1 502 ? 159.229 123.369 164.159 1.00 19.38  ? 502 VAL D CG2 1 
ATOM   18068 N N   . LEU D 1 503 ? 160.396 125.488 160.093 1.00 17.67  ? 503 LEU D N   1 
ATOM   18069 C CA  . LEU D 1 503 ? 160.281 126.082 158.758 1.00 22.29  ? 503 LEU D CA  1 
ATOM   18070 C C   . LEU D 1 503 ? 160.829 125.147 157.665 1.00 24.64  ? 503 LEU D C   1 
ATOM   18071 O O   . LEU D 1 503 ? 160.221 125.005 156.608 1.00 33.37  ? 503 LEU D O   1 
ATOM   18072 C CB  . LEU D 1 503 ? 160.965 127.460 158.757 1.00 29.73  ? 503 LEU D CB  1 
ATOM   18073 C CG  . LEU D 1 503 ? 160.909 128.197 157.405 1.00 33.12  ? 503 LEU D CG  1 
ATOM   18074 C CD1 . LEU D 1 503 ? 159.487 128.472 156.928 1.00 31.91  ? 503 LEU D CD1 1 
ATOM   18075 C CD2 . LEU D 1 503 ? 161.648 129.525 157.514 1.00 27.39  ? 503 LEU D CD2 1 
ATOM   18076 N N   . SER D 1 504 ? 161.929 124.444 157.936 1.00 26.84  ? 504 SER D N   1 
ATOM   18077 C CA  . SER D 1 504 ? 162.484 123.406 157.060 1.00 18.01  ? 504 SER D CA  1 
ATOM   18078 C C   . SER D 1 504 ? 161.548 122.219 156.891 1.00 18.47  ? 504 SER D C   1 
ATOM   18079 O O   . SER D 1 504 ? 161.465 121.662 155.805 1.00 27.40  ? 504 SER D O   1 
ATOM   18080 C CB  . SER D 1 504 ? 163.785 122.852 157.634 1.00 22.38  ? 504 SER D CB  1 
ATOM   18081 O OG  . SER D 1 504 ? 164.684 123.882 157.908 1.00 35.72  ? 504 SER D OG  1 
ATOM   18082 N N   . LEU D 1 505 ? 160.838 121.818 157.941 1.00 18.08  ? 505 LEU D N   1 
ATOM   18083 C CA  . LEU D 1 505 ? 159.841 120.758 157.913 1.00 20.29  ? 505 LEU D CA  1 
ATOM   18084 C C   . LEU D 1 505 ? 158.646 121.118 157.020 1.00 18.80  ? 505 LEU D C   1 
ATOM   18085 O O   . LEU D 1 505 ? 158.292 120.335 156.145 1.00 26.87  ? 505 LEU D O   1 
ATOM   18086 C CB  . LEU D 1 505 ? 159.425 120.475 159.364 1.00 23.03  ? 505 LEU D CB  1 
ATOM   18087 C CG  . LEU D 1 505 ? 158.301 119.455 159.559 1.00 21.68  ? 505 LEU D CG  1 
ATOM   18088 C CD1 . LEU D 1 505 ? 158.780 118.041 159.279 1.00 15.78  ? 505 LEU D CD1 1 
ATOM   18089 C CD2 . LEU D 1 505 ? 157.817 119.541 161.000 1.00 18.06  ? 505 LEU D CD2 1 
ATOM   18090 N N   . VAL D 1 506 ? 158.054 122.303 157.190 1.00 19.36  ? 506 VAL D N   1 
ATOM   18091 C CA  . VAL D 1 506 ? 156.946 122.772 156.345 1.00 21.50  ? 506 VAL D CA  1 
ATOM   18092 C C   . VAL D 1 506 ? 157.391 122.841 154.891 1.00 18.10  ? 506 VAL D C   1 
ATOM   18093 O O   . VAL D 1 506 ? 156.763 122.251 154.018 1.00 22.74  ? 506 VAL D O   1 
ATOM   18094 C CB  . VAL D 1 506 ? 156.417 124.145 156.798 1.00 17.91  ? 506 VAL D CB  1 
ATOM   18095 C CG1 . VAL D 1 506 ? 155.347 124.704 155.861 1.00 21.90  ? 506 VAL D CG1 1 
ATOM   18096 C CG2 . VAL D 1 506 ? 155.783 124.064 158.174 1.00 18.27  ? 506 VAL D CG2 1 
ATOM   18097 N N   . LEU D 1 507 ? 158.518 123.504 154.632 1.00 17.51  ? 507 LEU D N   1 
ATOM   18098 C CA  . LEU D 1 507 ? 159.064 123.648 153.295 1.00 13.80  ? 507 LEU D CA  1 
ATOM   18099 C C   . LEU D 1 507 ? 159.403 122.294 152.653 1.00 8.21   ? 507 LEU D C   1 
ATOM   18100 O O   . LEU D 1 507 ? 159.176 122.104 151.470 1.00 30.62  ? 507 LEU D O   1 
ATOM   18101 C CB  . LEU D 1 507 ? 160.255 124.603 153.399 1.00 22.46  ? 507 LEU D CB  1 
ATOM   18102 C CG  . LEU D 1 507 ? 160.888 124.994 152.064 1.00 28.93  ? 507 LEU D CG  1 
ATOM   18103 C CD1 . LEU D 1 507 ? 159.911 125.656 151.105 1.00 28.20  ? 507 LEU D CD1 1 
ATOM   18104 C CD2 . LEU D 1 507 ? 162.016 125.976 152.335 1.00 27.25  ? 507 LEU D CD2 1 
ATOM   18105 N N   . GLY D 1 508 ? 159.848 121.310 153.433 1.00 7.75   ? 508 GLY D N   1 
ATOM   18106 C CA  . GLY D 1 508 ? 160.077 119.948 152.970 1.00 0.00   ? 508 GLY D CA  1 
ATOM   18107 C C   . GLY D 1 508 ? 158.819 119.167 152.603 1.00 9.08   ? 508 GLY D C   1 
ATOM   18108 O O   . GLY D 1 508 ? 158.840 118.397 151.650 1.00 22.83  ? 508 GLY D O   1 
ATOM   18109 N N   . TRP D 1 509 ? 157.686 119.376 153.267 1.00 22.55  ? 509 TRP D N   1 
ATOM   18110 C CA  . TRP D 1 509 ? 156.414 118.785 152.840 1.00 10.17  ? 509 TRP D CA  1 
ATOM   18111 C C   . TRP D 1 509 ? 155.864 119.432 151.568 1.00 10.41  ? 509 TRP D C   1 
ATOM   18112 O O   . TRP D 1 509 ? 155.387 118.731 150.691 1.00 23.34  ? 509 TRP D O   1 
ATOM   18113 C CB  . TRP D 1 509 ? 155.412 118.770 153.999 1.00 16.41  ? 509 TRP D CB  1 
ATOM   18114 C CG  . TRP D 1 509 ? 155.678 117.649 154.949 1.00 17.24  ? 509 TRP D CG  1 
ATOM   18115 C CD1 . TRP D 1 509 ? 156.239 117.747 156.171 1.00 16.52  ? 509 TRP D CD1 1 
ATOM   18116 C CD2 . TRP D 1 509 ? 155.482 116.220 154.720 1.00 26.27  ? 509 TRP D CD2 1 
ATOM   18117 N NE1 . TRP D 1 509 ? 156.445 116.483 156.680 1.00 17.42  ? 509 TRP D NE1 1 
ATOM   18118 C CE2 . TRP D 1 509 ? 156.041 115.504 155.813 1.00 23.38  ? 509 TRP D CE2 1 
ATOM   18119 C CE3 . TRP D 1 509 ? 154.902 115.450 153.687 1.00 28.04  ? 509 TRP D CE3 1 
ATOM   18120 C CZ2 . TRP D 1 509 ? 156.094 114.103 155.852 1.00 18.55  ? 509 TRP D CZ2 1 
ATOM   18121 C CZ3 . TRP D 1 509 ? 154.941 114.043 153.722 1.00 28.77  ? 509 TRP D CZ3 1 
ATOM   18122 C CH2 . TRP D 1 509 ? 155.562 113.368 154.785 1.00 24.48  ? 509 TRP D CH2 1 
ATOM   18123 N N   . LEU D 1 510 ? 155.991 120.753 151.453 1.00 16.98  ? 510 LEU D N   1 
ATOM   18124 C CA  . LEU D 1 510 ? 155.651 121.489 150.242 1.00 15.45  ? 510 LEU D CA  1 
ATOM   18125 C C   . LEU D 1 510 ? 156.526 121.055 149.060 1.00 17.71  ? 510 LEU D C   1 
ATOM   18126 O O   . LEU D 1 510 ? 156.029 120.928 147.948 1.00 31.40  ? 510 LEU D O   1 
ATOM   18127 C CB  . LEU D 1 510 ? 155.754 122.996 150.515 1.00 25.60  ? 510 LEU D CB  1 
ATOM   18128 C CG  . LEU D 1 510 ? 154.797 123.526 151.596 1.00 21.98  ? 510 LEU D CG  1 
ATOM   18129 C CD1 . LEU D 1 510 ? 155.050 125.004 151.834 1.00 17.29  ? 510 LEU D CD1 1 
ATOM   18130 C CD2 . LEU D 1 510 ? 153.341 123.329 151.219 1.00 22.35  ? 510 LEU D CD2 1 
ATOM   18131 N N   . ASN D 1 511 ? 157.796 120.737 149.296 1.00 16.52  ? 511 ASN D N   1 
ATOM   18132 C CA  . ASN D 1 511 ? 158.702 120.181 148.297 1.00 4.47   ? 511 ASN D CA  1 
ATOM   18133 C C   . ASN D 1 511 ? 158.273 118.820 147.744 1.00 4.09   ? 511 ASN D C   1 
ATOM   18134 O O   . ASN D 1 511 ? 158.534 118.559 146.576 1.00 29.61  ? 511 ASN D O   1 
ATOM   18135 C CB  . ASN D 1 511 ? 160.114 120.115 148.874 1.00 9.82   ? 511 ASN D CB  1 
ATOM   18136 C CG  . ASN D 1 511 ? 160.830 121.445 148.899 1.00 11.41  ? 511 ASN D CG  1 
ATOM   18137 O OD1 . ASN D 1 511 ? 160.394 122.434 148.341 1.00 21.80  ? 511 ASN D OD1 1 
ATOM   18138 N ND2 . ASN D 1 511 ? 161.984 121.503 149.508 1.00 8.75   ? 511 ASN D ND2 1 
ATOM   18139 N N   . LEU D 1 512 ? 157.563 117.969 148.488 1.00 14.32  ? 512 LEU D N   1 
ATOM   18140 C CA  . LEU D 1 512 ? 157.035 116.710 147.940 1.00 7.02   ? 512 LEU D CA  1 
ATOM   18141 C C   . LEU D 1 512 ? 156.041 116.916 146.792 1.00 13.89  ? 512 LEU D C   1 
ATOM   18142 O O   . LEU D 1 512 ? 155.866 116.016 145.978 1.00 19.91  ? 512 LEU D O   1 
ATOM   18143 C CB  . LEU D 1 512 ? 156.404 115.851 149.047 1.00 15.26  ? 512 LEU D CB  1 
ATOM   18144 C CG  . LEU D 1 512 ? 157.451 115.083 149.860 1.00 21.07  ? 512 LEU D CG  1 
ATOM   18145 C CD1 . LEU D 1 512 ? 156.928 114.769 151.246 1.00 32.24  ? 512 LEU D CD1 1 
ATOM   18146 C CD2 . LEU D 1 512 ? 157.804 113.756 149.198 1.00 15.70  ? 512 LEU D CD2 1 
ATOM   18147 N N   . LEU D 1 513 ? 155.436 118.096 146.657 1.00 13.74  ? 513 LEU D N   1 
ATOM   18148 C CA  . LEU D 1 513 ? 154.562 118.413 145.534 1.00 14.71  ? 513 LEU D CA  1 
ATOM   18149 C C   . LEU D 1 513 ? 155.292 118.489 144.189 1.00 14.48  ? 513 LEU D C   1 
ATOM   18150 O O   . LEU D 1 513 ? 154.634 118.367 143.161 1.00 28.09  ? 513 LEU D O   1 
ATOM   18151 C CB  . LEU D 1 513 ? 153.776 119.696 145.815 1.00 25.49  ? 513 LEU D CB  1 
ATOM   18152 C CG  . LEU D 1 513 ? 152.833 119.579 147.023 1.00 21.25  ? 513 LEU D CG  1 
ATOM   18153 C CD1 . LEU D 1 513 ? 152.320 120.963 147.385 1.00 19.06  ? 513 LEU D CD1 1 
ATOM   18154 C CD2 . LEU D 1 513 ? 151.646 118.665 146.726 1.00 12.81  ? 513 LEU D CD2 1 
ATOM   18155 N N   . TYR D 1 514 ? 156.624 118.588 144.175 1.00 14.47  ? 514 TYR D N   1 
ATOM   18156 C CA  . TYR D 1 514 ? 157.439 118.434 142.975 1.00 5.89   ? 514 TYR D CA  1 
ATOM   18157 C C   . TYR D 1 514 ? 157.153 117.111 142.252 1.00 11.67  ? 514 TYR D C   1 
ATOM   18158 O O   . TYR D 1 514 ? 156.926 117.089 141.047 1.00 30.46  ? 514 TYR D O   1 
ATOM   18159 C CB  . TYR D 1 514 ? 158.915 118.520 143.373 1.00 12.68  ? 514 TYR D CB  1 
ATOM   18160 C CG  . TYR D 1 514 ? 159.872 118.177 142.258 1.00 16.49  ? 514 TYR D CG  1 
ATOM   18161 C CD1 . TYR D 1 514 ? 160.194 119.129 141.278 1.00 12.12  ? 514 TYR D CD1 1 
ATOM   18162 C CD2 . TYR D 1 514 ? 160.378 116.870 142.162 1.00 15.27  ? 514 TYR D CD2 1 
ATOM   18163 C CE1 . TYR D 1 514 ? 161.011 118.762 140.194 1.00 11.45  ? 514 TYR D CE1 1 
ATOM   18164 C CE2 . TYR D 1 514 ? 161.174 116.492 141.074 1.00 6.72   ? 514 TYR D CE2 1 
ATOM   18165 C CZ  . TYR D 1 514 ? 161.484 117.441 140.081 1.00 11.98  ? 514 TYR D CZ  1 
ATOM   18166 O OH  . TYR D 1 514 ? 162.249 117.094 139.020 1.00 30.84  ? 514 TYR D OH  1 
ATOM   18167 N N   . TYR D 1 515 ? 157.107 116.002 142.990 1.00 21.80  ? 515 TYR D N   1 
ATOM   18168 C CA  . TYR D 1 515 ? 156.988 114.657 142.434 1.00 13.81  ? 515 TYR D CA  1 
ATOM   18169 C C   . TYR D 1 515 ? 155.604 114.333 141.874 1.00 9.76   ? 515 TYR D C   1 
ATOM   18170 O O   . TYR D 1 515 ? 155.424 113.310 141.227 1.00 21.92  ? 515 TYR D O   1 
ATOM   18171 C CB  . TYR D 1 515 ? 157.452 113.623 143.459 1.00 12.60  ? 515 TYR D CB  1 
ATOM   18172 C CG  . TYR D 1 515 ? 158.867 113.842 143.939 1.00 17.10  ? 515 TYR D CG  1 
ATOM   18173 C CD1 . TYR D 1 515 ? 159.962 113.359 143.198 1.00 15.80  ? 515 TYR D CD1 1 
ATOM   18174 C CD2 . TYR D 1 515 ? 159.084 114.551 145.132 1.00 7.40   ? 515 TYR D CD2 1 
ATOM   18175 C CE1 . TYR D 1 515 ? 161.275 113.578 143.653 1.00 11.60  ? 515 TYR D CE1 1 
ATOM   18176 C CE2 . TYR D 1 515 ? 160.389 114.767 145.589 1.00 13.61  ? 515 TYR D CE2 1 
ATOM   18177 C CZ  . TYR D 1 515 ? 161.486 114.285 144.852 1.00 15.97  ? 515 TYR D CZ  1 
ATOM   18178 O OH  . TYR D 1 515 ? 162.732 114.526 145.315 1.00 20.50  ? 515 TYR D OH  1 
ATOM   18179 N N   . THR D 1 516 ? 154.633 115.238 142.001 1.00 10.98  ? 516 THR D N   1 
ATOM   18180 C CA  . THR D 1 516 ? 153.332 115.095 141.336 1.00 17.12  ? 516 THR D CA  1 
ATOM   18181 C C   . THR D 1 516 ? 153.448 115.038 139.813 1.00 21.82  ? 516 THR D C   1 
ATOM   18182 O O   . THR D 1 516 ? 152.580 114.439 139.187 1.00 37.61  ? 516 THR D O   1 
ATOM   18183 C CB  . THR D 1 516 ? 152.341 116.194 141.732 1.00 22.25  ? 516 THR D CB  1 
ATOM   18184 O OG1 . THR D 1 516 ? 152.795 117.466 141.359 1.00 31.57  ? 516 THR D OG1 1 
ATOM   18185 C CG2 . THR D 1 516 ? 151.998 116.189 143.212 1.00 11.50  ? 516 THR D CG2 1 
ATOM   18186 N N   . ARG D 1 517 ? 154.524 115.561 139.208 1.00 17.60  ? 517 ARG D N   1 
ATOM   18187 C CA  . ARG D 1 517 ? 154.835 115.456 137.768 1.00 9.33   ? 517 ARG D CA  1 
ATOM   18188 C C   . ARG D 1 517 ? 155.157 114.046 137.261 1.00 18.53  ? 517 ARG D C   1 
ATOM   18189 O O   . ARG D 1 517 ? 155.162 113.839 136.051 1.00 32.44  ? 517 ARG D O   1 
ATOM   18190 C CB  . ARG D 1 517 ? 155.941 116.456 137.407 1.00 17.52  ? 517 ARG D CB  1 
ATOM   18191 C CG  . ARG D 1 517 ? 157.336 116.048 137.907 1.00 19.87  ? 517 ARG D CG  1 
ATOM   18192 C CD  . ARG D 1 517 ? 158.368 117.163 137.802 1.00 5.49   ? 517 ARG D CD  1 
ATOM   18193 N NE  . ARG D 1 517 ? 157.932 118.345 138.560 1.00 19.08  ? 517 ARG D NE  1 
ATOM   18194 C CZ  . ARG D 1 517 ? 158.166 119.602 138.266 1.00 17.22  ? 517 ARG D CZ  1 
ATOM   18195 N NH1 . ARG D 1 517 ? 157.497 120.548 138.838 1.00 12.05  ? 517 ARG D NH1 1 
ATOM   18196 N NH2 . ARG D 1 517 ? 159.060 119.943 137.390 1.00 24.62  ? 517 ARG D NH2 1 
ATOM   18197 N N   . GLY D 1 518 ? 155.394 113.074 138.141 1.00 27.90  ? 518 GLY D N   1 
ATOM   18198 C CA  . GLY D 1 518 ? 155.680 111.690 137.766 1.00 21.23  ? 518 GLY D CA  1 
ATOM   18199 C C   . GLY D 1 518 ? 154.497 110.936 137.158 1.00 21.86  ? 518 GLY D C   1 
ATOM   18200 O O   . GLY D 1 518 ? 154.704 109.989 136.405 1.00 39.14  ? 518 GLY D O   1 
ATOM   18201 N N   . PHE D 1 519 ? 153.268 111.366 137.432 1.00 10.80  ? 519 PHE D N   1 
ATOM   18202 C CA  . PHE D 1 519 ? 152.045 110.775 136.894 1.00 21.77  ? 519 PHE D CA  1 
ATOM   18203 C C   . PHE D 1 519 ? 151.299 111.787 136.042 1.00 28.02  ? 519 PHE D C   1 
ATOM   18204 O O   . PHE D 1 519 ? 151.238 112.960 136.395 1.00 31.45  ? 519 PHE D O   1 
ATOM   18205 C CB  . PHE D 1 519 ? 151.129 110.287 138.021 1.00 25.26  ? 519 PHE D CB  1 
ATOM   18206 C CG  . PHE D 1 519 ? 151.767 109.318 138.988 1.00 24.89  ? 519 PHE D CG  1 
ATOM   18207 C CD1 . PHE D 1 519 ? 152.004 107.991 138.594 1.00 23.56  ? 519 PHE D CD1 1 
ATOM   18208 C CD2 . PHE D 1 519 ? 152.115 109.742 140.279 1.00 25.48  ? 519 PHE D CD2 1 
ATOM   18209 C CE1 . PHE D 1 519 ? 152.586 107.086 139.494 1.00 27.79  ? 519 PHE D CE1 1 
ATOM   18210 C CE2 . PHE D 1 519 ? 152.685 108.834 141.182 1.00 32.69  ? 519 PHE D CE2 1 
ATOM   18211 C CZ  . PHE D 1 519 ? 152.919 107.506 140.790 1.00 29.14  ? 519 PHE D CZ  1 
ATOM   18212 N N   . GLN D 1 520 ? 150.681 111.348 134.953 1.00 40.23  ? 520 GLN D N   1 
ATOM   18213 C CA  . GLN D 1 520 ? 149.924 112.237 134.073 1.00 34.08  ? 520 GLN D CA  1 
ATOM   18214 C C   . GLN D 1 520 ? 148.763 112.919 134.794 1.00 35.19  ? 520 GLN D C   1 
ATOM   18215 O O   . GLN D 1 520 ? 148.562 114.118 134.647 1.00 35.74  ? 520 GLN D O   1 
ATOM   18216 C CB  . GLN D 1 520 ? 149.456 111.428 132.858 1.00 33.61  ? 520 GLN D CB  1 
ATOM   18217 C CG  . GLN D 1 520 ? 148.776 112.313 131.810 1.00 35.52  ? 520 GLN D CG  1 
ATOM   18218 C CD  . GLN D 1 520 ? 148.598 111.639 130.452 1.00 39.99  ? 520 GLN D CD  1 
ATOM   18219 O OE1 . GLN D 1 520 ? 149.348 110.770 130.035 1.00 43.46  ? 520 GLN D OE1 1 
ATOM   18220 N NE2 . GLN D 1 520 ? 147.598 112.023 129.700 1.00 43.24  ? 520 GLN D NE2 1 
ATOM   18221 N N   . HIS D 1 521 ? 148.028 112.174 135.621 1.00 38.54  ? 521 HIS D N   1 
ATOM   18222 C CA  . HIS D 1 521 ? 146.821 112.654 136.292 1.00 36.47  ? 521 HIS D CA  1 
ATOM   18223 C C   . HIS D 1 521 ? 147.109 113.793 137.276 1.00 35.33  ? 521 HIS D C   1 
ATOM   18224 O O   . HIS D 1 521 ? 146.506 114.867 137.106 1.00 37.80  ? 521 HIS D O   1 
ATOM   18225 C CB  . HIS D 1 521 ? 146.095 111.505 137.007 1.00 36.51  ? 521 HIS D CB  1 
ATOM   18226 C CG  . HIS D 1 521 ? 144.707 111.865 137.418 1.00 42.93  ? 521 HIS D CG  1 
ATOM   18227 N ND1 . HIS D 1 521 ? 144.194 111.545 138.661 1.00 45.28  ? 521 HIS D ND1 1 
ATOM   18228 C CD2 . HIS D 1 521 ? 143.727 112.526 136.764 1.00 37.78  ? 521 HIS D CD2 1 
ATOM   18229 C CE1 . HIS D 1 521 ? 142.955 111.986 138.750 1.00 44.11  ? 521 HIS D CE1 1 
ATOM   18230 N NE2 . HIS D 1 521 ? 142.645 112.593 137.599 1.00 44.67  ? 521 HIS D NE2 1 
ATOM   18231 N N   . THR D 1 522 ? 148.032 113.603 138.222 1.00 34.79  ? 522 THR D N   1 
ATOM   18232 C CA  . THR D 1 522 ? 148.411 114.682 139.173 1.00 32.05  ? 522 THR D CA  1 
ATOM   18233 C C   . THR D 1 522 ? 149.277 115.720 138.451 1.00 32.05  ? 522 THR D C   1 
ATOM   18234 O O   . THR D 1 522 ? 149.005 116.925 138.616 1.00 25.81  ? 522 THR D O   1 
ATOM   18235 C CB  . THR D 1 522 ? 149.136 114.106 140.396 1.00 33.41  ? 522 THR D CB  1 
ATOM   18236 O OG1 . THR D 1 522 ? 150.318 113.449 139.938 1.00 32.17  ? 522 THR D OG1 1 
ATOM   18237 C CG2 . THR D 1 522 ? 148.282 113.133 141.179 1.00 26.45  ? 522 THR D CG2 1 
ATOM   18238 N N   . GLY D 1 523 ? 150.274 115.264 137.685 1.00 36.86  ? 523 GLY D N   1 
ATOM   18239 C CA  . GLY D 1 523 ? 151.169 116.186 136.959 1.00 24.07  ? 523 GLY D CA  1 
ATOM   18240 C C   . GLY D 1 523 ? 150.396 117.277 136.241 1.00 31.16  ? 523 GLY D C   1 
ATOM   18241 O O   . GLY D 1 523 ? 150.549 118.455 136.621 1.00 49.85  ? 523 GLY D O   1 
ATOM   18242 N N   . ILE D 1 524 ? 149.593 116.903 135.241 1.00 29.92  ? 524 ILE D N   1 
ATOM   18243 C CA  . ILE D 1 524 ? 148.817 117.887 134.478 1.00 31.74  ? 524 ILE D CA  1 
ATOM   18244 C C   . ILE D 1 524 ? 147.979 118.770 135.415 1.00 41.79  ? 524 ILE D C   1 
ATOM   18245 O O   . ILE D 1 524 ? 147.877 119.974 135.179 1.00 42.74  ? 524 ILE D O   1 
ATOM   18246 C CB  . ILE D 1 524 ? 147.974 117.163 133.408 1.00 41.04  ? 524 ILE D CB  1 
ATOM   18247 C CG1 . ILE D 1 524 ? 148.925 116.560 132.353 1.00 34.90  ? 524 ILE D CG1 1 
ATOM   18248 C CG2 . ILE D 1 524 ? 146.963 118.098 132.734 1.00 35.45  ? 524 ILE D CG2 1 
ATOM   18249 C CD1 . ILE D 1 524 ? 148.227 115.783 131.244 1.00 31.89  ? 524 ILE D CD1 1 
ATOM   18250 N N   . TYR D 1 525 ? 147.427 118.240 136.511 1.00 37.19  ? 525 TYR D N   1 
ATOM   18251 C CA  . TYR D 1 525 ? 146.676 119.072 137.455 1.00 33.71  ? 525 TYR D CA  1 
ATOM   18252 C C   . TYR D 1 525 ? 147.551 120.095 138.177 1.00 37.89  ? 525 TYR D C   1 
ATOM   18253 O O   . TYR D 1 525 ? 147.173 121.258 138.296 1.00 44.93  ? 525 TYR D O   1 
ATOM   18254 C CB  . TYR D 1 525 ? 145.918 118.214 138.458 1.00 40.27  ? 525 TYR D CB  1 
ATOM   18255 C CG  . TYR D 1 525 ? 144.872 119.008 139.208 1.00 34.78  ? 525 TYR D CG  1 
ATOM   18256 C CD1 . TYR D 1 525 ? 143.744 119.473 138.511 1.00 31.38  ? 525 TYR D CD1 1 
ATOM   18257 C CD2 . TYR D 1 525 ? 145.056 119.349 140.561 1.00 32.65  ? 525 TYR D CD2 1 
ATOM   18258 C CE1 . TYR D 1 525 ? 142.784 120.262 139.161 1.00 43.21  ? 525 TYR D CE1 1 
ATOM   18259 C CE2 . TYR D 1 525 ? 144.096 120.144 141.213 1.00 41.04  ? 525 TYR D CE2 1 
ATOM   18260 C CZ  . TYR D 1 525 ? 142.956 120.601 140.518 1.00 43.96  ? 525 TYR D CZ  1 
ATOM   18261 O OH  . TYR D 1 525 ? 142.046 121.391 141.141 1.00 32.72  ? 525 TYR D OH  1 
ATOM   18262 N N   . SER D 1 526 ? 148.759 119.715 138.577 1.00 26.86  ? 526 SER D N   1 
ATOM   18263 C CA  . SER D 1 526 ? 149.752 120.652 139.096 1.00 34.60  ? 526 SER D CA  1 
ATOM   18264 C C   . SER D 1 526 ? 150.042 121.816 138.134 1.00 39.72  ? 526 SER D C   1 
ATOM   18265 O O   . SER D 1 526 ? 150.247 122.936 138.589 1.00 48.34  ? 526 SER D O   1 
ATOM   18266 C CB  . SER D 1 526 ? 151.015 119.872 139.441 1.00 40.06  ? 526 SER D CB  1 
ATOM   18267 O OG  . SER D 1 526 ? 150.813 119.196 140.661 1.00 46.67  ? 526 SER D OG  1 
ATOM   18268 N N   . VAL D 1 527 ? 149.934 121.605 136.820 1.00 39.54  ? 527 VAL D N   1 
ATOM   18269 C CA  . VAL D 1 527 ? 150.014 122.659 135.799 1.00 40.11  ? 527 VAL D CA  1 
ATOM   18270 C C   . VAL D 1 527 ? 148.724 123.484 135.667 1.00 40.47  ? 527 VAL D C   1 
ATOM   18271 O O   . VAL D 1 527 ? 148.787 124.707 135.607 1.00 42.00  ? 527 VAL D O   1 
ATOM   18272 C CB  . VAL D 1 527 ? 150.407 122.048 134.445 1.00 40.79  ? 527 VAL D CB  1 
ATOM   18273 C CG1 . VAL D 1 527 ? 150.379 123.087 133.336 1.00 42.41  ? 527 VAL D CG1 1 
ATOM   18274 C CG2 . VAL D 1 527 ? 151.817 121.465 134.483 1.00 35.77  ? 527 VAL D CG2 1 
ATOM   18275 N N   . MET D 1 528 ? 147.545 122.856 135.667 1.00 47.86  ? 528 MET D N   1 
ATOM   18276 C CA  . MET D 1 528 ? 146.248 123.558 135.678 1.00 47.15  ? 528 MET D CA  1 
ATOM   18277 C C   . MET D 1 528 ? 146.108 124.501 136.888 1.00 48.01  ? 528 MET D C   1 
ATOM   18278 O O   . MET D 1 528 ? 145.603 125.612 136.770 1.00 49.95  ? 528 MET D O   1 
ATOM   18279 C CB  . MET D 1 528 ? 145.107 122.531 135.703 1.00 47.41  ? 528 MET D CB  1 
ATOM   18280 C CG  . MET D 1 528 ? 145.013 121.699 134.423 1.00 49.07  ? 528 MET D CG  1 
ATOM   18281 S SD  . MET D 1 528 ? 143.954 120.239 134.613 1.00 66.06  ? 528 MET D SD  1 
ATOM   18282 C CE  . MET D 1 528 ? 143.552 119.944 132.873 1.00 50.00  ? 528 MET D CE  1 
ATOM   18283 N N   . ILE D 1 529 ? 146.623 124.087 138.043 1.00 51.56  ? 529 ILE D N   1 
ATOM   18284 C CA  . ILE D 1 529 ? 146.610 124.878 139.319 1.00 51.31  ? 529 ILE D CA  1 
ATOM   18285 C C   . ILE D 1 529 ? 147.614 126.046 139.316 1.00 51.87  ? 529 ILE D C   1 
ATOM   18286 O O   . ILE D 1 529 ? 147.632 126.794 140.284 1.00 60.31  ? 529 ILE D O   1 
ATOM   18287 C CB  . ILE D 1 529 ? 146.846 123.947 140.525 1.00 52.74  ? 529 ILE D CB  1 
ATOM   18288 C CG1 . ILE D 1 529 ? 145.655 123.014 140.752 1.00 54.40  ? 529 ILE D CG1 1 
ATOM   18289 C CG2 . ILE D 1 529 ? 147.174 124.753 141.773 1.00 53.01  ? 529 ILE D CG2 1 
ATOM   18290 C CD1 . ILE D 1 529 ? 144.347 123.739 140.966 1.00 46.50  ? 529 ILE D CD1 1 
ATOM   18291 N N   . GLN D 1 530 ? 148.374 126.321 138.253 1.00 47.24  ? 530 GLN D N   1 
ATOM   18292 C CA  . GLN D 1 530 ? 149.184 127.549 138.146 1.00 41.59  ? 530 GLN D CA  1 
ATOM   18293 C C   . GLN D 1 530 ? 148.407 128.785 137.641 1.00 45.96  ? 530 GLN D C   1 
ATOM   18294 O O   . GLN D 1 530 ? 148.985 129.867 137.620 1.00 48.08  ? 530 GLN D O   1 
ATOM   18295 C CB  . GLN D 1 530 ? 150.400 127.317 137.236 1.00 51.71  ? 530 GLN D CB  1 
ATOM   18296 C CG  . GLN D 1 530 ? 151.263 126.100 137.580 1.00 53.26  ? 530 GLN D CG  1 
ATOM   18297 C CD  . GLN D 1 530 ? 151.847 126.137 138.981 1.00 50.21  ? 530 GLN D CD  1 
ATOM   18298 O OE1 . GLN D 1 530 ? 152.549 127.054 139.373 1.00 57.01  ? 530 GLN D OE1 1 
ATOM   18299 N NE2 . GLN D 1 530 ? 151.635 125.106 139.759 1.00 48.20  ? 530 GLN D NE2 1 
ATOM   18300 N N   . LYS D 1 531 ? 147.143 128.663 137.203 1.00 47.06  ? 531 LYS D N   1 
ATOM   18301 C CA  . LYS D 1 531 ? 146.340 129.708 136.519 1.00 46.17  ? 531 LYS D CA  1 
ATOM   18302 C C   . LYS D 1 531 ? 146.549 131.130 137.048 1.00 49.37  ? 531 LYS D C   1 
ATOM   18303 O O   . LYS D 1 531 ? 146.869 132.040 136.289 1.00 51.03  ? 531 LYS D O   1 
ATOM   18304 C CB  . LYS D 1 531 ? 144.834 129.354 136.633 1.00 46.33  ? 531 LYS D CB  1 
ATOM   18305 C CG  . LYS D 1 531 ? 144.288 128.468 135.507 1.00 46.96  ? 531 LYS D CG  1 
ATOM   18306 C CD  . LYS D 1 531 ? 144.018 129.258 134.222 1.00 48.94  ? 531 LYS D CD  1 
ATOM   18307 C CE  . LYS D 1 531 ? 143.345 128.364 133.174 1.00 52.22  ? 531 LYS D CE  1 
ATOM   18308 N NZ  . LYS D 1 531 ? 143.036 129.102 131.918 1.00 52.14  ? 531 LYS D NZ  1 
ATOM   18309 N N   . VAL D 1 532 ? 146.324 131.326 138.342 1.00 54.32  ? 532 VAL D N   1 
ATOM   18310 C CA  . VAL D 1 532 ? 146.430 132.596 139.066 1.00 49.39  ? 532 VAL D CA  1 
ATOM   18311 C C   . VAL D 1 532 ? 147.867 132.756 139.554 1.00 54.18  ? 532 VAL D C   1 
ATOM   18312 O O   . VAL D 1 532 ? 148.259 132.277 140.620 1.00 57.59  ? 532 VAL D O   1 
ATOM   18313 C CB  . VAL D 1 532 ? 145.400 132.655 140.209 1.00 50.48  ? 532 VAL D CB  1 
ATOM   18314 C CG1 . VAL D 1 532 ? 145.493 133.974 140.971 1.00 51.39  ? 532 VAL D CG1 1 
ATOM   18315 C CG2 . VAL D 1 532 ? 143.976 132.506 139.656 1.00 49.75  ? 532 VAL D CG2 1 
ATOM   18316 N N   . ILE D 1 533 ? 148.680 133.406 138.724 1.00 59.56  ? 533 ILE D N   1 
ATOM   18317 C CA  . ILE D 1 533 ? 150.082 133.717 139.013 1.00 58.40  ? 533 ILE D CA  1 
ATOM   18318 C C   . ILE D 1 533 ? 150.140 134.726 140.175 1.00 51.11  ? 533 ILE D C   1 
ATOM   18319 O O   . ILE D 1 533 ? 149.202 135.493 140.399 1.00 49.52  ? 533 ILE D O   1 
ATOM   18320 C CB  . ILE D 1 533 ? 150.775 134.245 137.721 1.00 53.51  ? 533 ILE D CB  1 
ATOM   18321 C CG1 . ILE D 1 533 ? 150.545 133.346 136.482 1.00 50.59  ? 533 ILE D CG1 1 
ATOM   18322 C CG2 . ILE D 1 533 ? 152.294 134.444 137.875 1.00 52.75  ? 533 ILE D CG2 1 
ATOM   18323 C CD1 . ILE D 1 533 ? 151.197 131.964 136.555 1.00 48.41  ? 533 ILE D CD1 1 
ATOM   18324 N N   . LEU D 1 534 ? 151.275 134.831 140.864 1.00 46.49  ? 534 LEU D N   1 
ATOM   18325 C CA  . LEU D 1 534 ? 151.541 135.971 141.750 1.00 47.81  ? 534 LEU D CA  1 
ATOM   18326 C C   . LEU D 1 534 ? 151.485 137.331 141.032 1.00 49.02  ? 534 LEU D C   1 
ATOM   18327 O O   . LEU D 1 534 ? 151.416 138.347 141.702 1.00 55.50  ? 534 LEU D O   1 
ATOM   18328 C CB  . LEU D 1 534 ? 152.898 135.797 142.455 1.00 52.10  ? 534 LEU D CB  1 
ATOM   18329 C CG  . LEU D 1 534 ? 153.004 134.568 143.371 1.00 54.72  ? 534 LEU D CG  1 
ATOM   18330 C CD1 . LEU D 1 534 ? 154.418 134.500 143.941 1.00 53.65  ? 534 LEU D CD1 1 
ATOM   18331 C CD2 . LEU D 1 534 ? 152.008 134.624 144.527 1.00 52.05  ? 534 LEU D CD2 1 
ATOM   18332 N N   . ARG D 1 535 ? 151.455 137.338 139.694 1.00 47.02  ? 535 ARG D N   1 
ATOM   18333 C CA  . ARG D 1 535 ? 151.412 138.597 138.887 1.00 47.10  ? 535 ARG D CA  1 
ATOM   18334 C C   . ARG D 1 535 ? 150.274 139.506 139.365 1.00 47.08  ? 535 ARG D C   1 
ATOM   18335 O O   . ARG D 1 535 ? 150.537 140.705 139.584 1.00 48.92  ? 535 ARG D O   1 
ATOM   18336 C CB  . ARG D 1 535 ? 151.269 138.195 137.411 1.00 49.32  ? 535 ARG D CB  1 
ATOM   18337 C CG  . ARG D 1 535 ? 151.464 139.366 136.437 1.00 47.93  ? 535 ARG D CG  1 
ATOM   18338 C CD  . ARG D 1 535 ? 150.800 139.078 135.092 1.00 47.60  ? 535 ARG D CD  1 
ATOM   18339 N NE  . ARG D 1 535 ? 149.353 139.005 135.243 1.00 50.84  ? 535 ARG D NE  1 
ATOM   18340 C CZ  . ARG D 1 535 ? 148.494 138.827 134.246 1.00 51.33  ? 535 ARG D CZ  1 
ATOM   18341 N NH1 . ARG D 1 535 ? 147.197 138.777 134.494 1.00 45.90  ? 535 ARG D NH1 1 
ATOM   18342 N NH2 . ARG D 1 535 ? 148.935 138.702 133.007 1.00 49.27  ? 535 ARG D NH2 1 
ATOM   18343 N N   . ASP D 1 536 ? 149.065 138.960 139.517 1.00 41.47  ? 536 ASP D N   1 
ATOM   18344 C CA  . ASP D 1 536 ? 147.906 139.760 139.926 1.00 37.39  ? 536 ASP D CA  1 
ATOM   18345 C C   . ASP D 1 536 ? 147.746 139.818 141.440 1.00 40.90  ? 536 ASP D C   1 
ATOM   18346 O O   . ASP D 1 536 ? 147.505 140.888 141.982 1.00 46.81  ? 536 ASP D O   1 
ATOM   18347 C CB  . ASP D 1 536 ? 146.633 139.303 139.212 1.00 40.80  ? 536 ASP D CB  1 
ATOM   18348 C CG  . ASP D 1 536 ? 146.664 139.604 137.707 1.00 46.75  ? 536 ASP D CG  1 
ATOM   18349 O OD1 . ASP D 1 536 ? 147.673 140.154 137.214 1.00 46.54  ? 536 ASP D OD1 1 
ATOM   18350 O OD2 . ASP D 1 536 ? 145.700 139.286 136.989 1.00 47.40  ? 536 ASP D OD2 1 
ATOM   18351 N N   . LEU D 1 537 ? 147.957 138.720 142.162 1.00 39.50  ? 537 LEU D N   1 
ATOM   18352 C CA  . LEU D 1 537 ? 147.828 138.727 143.617 1.00 33.77  ? 537 LEU D CA  1 
ATOM   18353 C C   . LEU D 1 537 ? 148.886 139.582 144.322 1.00 40.21  ? 537 LEU D C   1 
ATOM   18354 O O   . LEU D 1 537 ? 148.551 140.212 145.314 1.00 49.38  ? 537 LEU D O   1 
ATOM   18355 C CB  . LEU D 1 537 ? 147.762 137.289 144.153 1.00 36.89  ? 537 LEU D CB  1 
ATOM   18356 C CG  . LEU D 1 537 ? 146.311 136.884 144.430 1.00 41.91  ? 537 LEU D CG  1 
ATOM   18357 C CD1 . LEU D 1 537 ? 145.424 136.929 143.192 1.00 41.74  ? 537 LEU D CD1 1 
ATOM   18358 C CD2 . LEU D 1 537 ? 146.275 135.479 145.000 1.00 44.21  ? 537 LEU D CD2 1 
ATOM   18359 N N   . LEU D 1 538 ? 150.113 139.707 143.809 1.00 40.83  ? 538 LEU D N   1 
ATOM   18360 C CA  . LEU D 1 538 ? 151.110 140.638 144.347 1.00 43.94  ? 538 LEU D CA  1 
ATOM   18361 C C   . LEU D 1 538 ? 150.753 142.111 144.076 1.00 40.94  ? 538 LEU D C   1 
ATOM   18362 O O   . LEU D 1 538 ? 151.114 142.992 144.851 1.00 45.46  ? 538 LEU D O   1 
ATOM   18363 C CB  . LEU D 1 538 ? 152.493 140.263 143.775 1.00 44.76  ? 538 LEU D CB  1 
ATOM   18364 C CG  . LEU D 1 538 ? 153.694 141.045 144.319 1.00 46.80  ? 538 LEU D CG  1 
ATOM   18365 C CD1 . LEU D 1 538 ? 153.854 140.909 145.823 1.00 43.12  ? 538 LEU D CD1 1 
ATOM   18366 C CD2 . LEU D 1 538 ? 154.964 140.526 143.664 1.00 43.33  ? 538 LEU D CD2 1 
ATOM   18367 N N   . ARG D 1 539 ? 149.975 142.352 143.007 1.00 32.43  ? 539 ARG D N   1 
ATOM   18368 C CA  . ARG D 1 539 ? 149.510 143.737 142.679 1.00 30.20  ? 539 ARG D CA  1 
ATOM   18369 C C   . ARG D 1 539 ? 148.308 144.054 143.579 1.00 34.69  ? 539 ARG D C   1 
ATOM   18370 O O   . ARG D 1 539 ? 148.320 145.131 144.207 1.00 46.82  ? 539 ARG D O   1 
ATOM   18371 C CB  . ARG D 1 539 ? 149.347 143.871 141.162 1.00 41.51  ? 539 ARG D CB  1 
ATOM   18372 C CG  . ARG D 1 539 ? 150.688 143.793 140.426 1.00 42.33  ? 539 ARG D CG  1 
ATOM   18373 C CD  . ARG D 1 539 ? 150.544 144.186 138.956 1.00 38.32  ? 539 ARG D CD  1 
ATOM   18374 N NE  . ARG D 1 539 ? 149.677 143.267 138.233 1.00 40.36  ? 539 ARG D NE  1 
ATOM   18375 C CZ  . ARG D 1 539 ? 149.417 143.341 136.932 1.00 41.43  ? 539 ARG D CZ  1 
ATOM   18376 N NH1 . ARG D 1 539 ? 148.614 142.457 136.366 1.00 39.17  ? 539 ARG D NH1 1 
ATOM   18377 N NH2 . ARG D 1 539 ? 149.963 144.297 136.202 1.00 36.79  ? 539 ARG D NH2 1 
ATOM   18378 N N   . PHE D 1 540 ? 147.323 143.159 143.652 1.00 36.16  ? 540 PHE D N   1 
ATOM   18379 C CA  . PHE D 1 540 ? 146.198 143.289 144.584 1.00 31.41  ? 540 PHE D CA  1 
ATOM   18380 C C   . PHE D 1 540 ? 146.691 143.478 146.020 1.00 25.90  ? 540 PHE D C   1 
ATOM   18381 O O   . PHE D 1 540 ? 146.160 144.319 146.741 1.00 28.93  ? 540 PHE D O   1 
ATOM   18382 C CB  . PHE D 1 540 ? 145.285 142.059 144.454 1.00 31.28  ? 540 PHE D CB  1 
ATOM   18383 C CG  . PHE D 1 540 ? 144.573 141.652 145.729 1.00 38.71  ? 540 PHE D CG  1 
ATOM   18384 C CD1 . PHE D 1 540 ? 143.387 142.297 146.133 1.00 36.41  ? 540 PHE D CD1 1 
ATOM   18385 C CD2 . PHE D 1 540 ? 145.133 140.652 146.547 1.00 35.25  ? 540 PHE D CD2 1 
ATOM   18386 C CE1 . PHE D 1 540 ? 142.782 141.953 147.350 1.00 27.55  ? 540 PHE D CE1 1 
ATOM   18387 C CE2 . PHE D 1 540 ? 144.545 140.331 147.776 1.00 32.86  ? 540 PHE D CE2 1 
ATOM   18388 C CZ  . PHE D 1 540 ? 143.369 140.983 148.176 1.00 33.03  ? 540 PHE D CZ  1 
ATOM   18389 N N   . LEU D 1 541 ? 147.738 142.756 146.421 1.00 19.20  ? 541 LEU D N   1 
ATOM   18390 C CA  . LEU D 1 541 ? 148.323 142.852 147.746 1.00 28.68  ? 541 LEU D CA  1 
ATOM   18391 C C   . LEU D 1 541 ? 148.814 144.263 148.068 1.00 29.19  ? 541 LEU D C   1 
ATOM   18392 O O   . LEU D 1 541 ? 148.610 144.723 149.179 1.00 37.90  ? 541 LEU D O   1 
ATOM   18393 C CB  . LEU D 1 541 ? 149.444 141.807 147.868 1.00 33.04  ? 541 LEU D CB  1 
ATOM   18394 C CG  . LEU D 1 541 ? 150.113 141.740 149.246 1.00 32.91  ? 541 LEU D CG  1 
ATOM   18395 C CD1 . LEU D 1 541 ? 149.159 141.200 150.310 1.00 30.39  ? 541 LEU D CD1 1 
ATOM   18396 C CD2 . LEU D 1 541 ? 151.320 140.818 149.168 1.00 32.93  ? 541 LEU D CD2 1 
ATOM   18397 N N   . LEU D 1 542 ? 149.384 144.996 147.108 1.00 26.34  ? 542 LEU D N   1 
ATOM   18398 C CA  . LEU D 1 542 ? 149.758 146.394 147.298 1.00 22.34  ? 542 LEU D CA  1 
ATOM   18399 C C   . LEU D 1 542 ? 148.559 147.267 147.693 1.00 20.49  ? 542 LEU D C   1 
ATOM   18400 O O   . LEU D 1 542 ? 148.621 147.995 148.676 1.00 32.24  ? 542 LEU D O   1 
ATOM   18401 C CB  . LEU D 1 542 ? 150.450 146.892 146.015 1.00 28.65  ? 542 LEU D CB  1 
ATOM   18402 C CG  . LEU D 1 542 ? 150.871 148.371 146.033 1.00 29.21  ? 542 LEU D CG  1 
ATOM   18403 C CD1 . LEU D 1 542 ? 151.933 148.659 147.085 1.00 31.51  ? 542 LEU D CD1 1 
ATOM   18404 C CD2 . LEU D 1 542 ? 151.435 148.749 144.673 1.00 23.63  ? 542 LEU D CD2 1 
ATOM   18405 N N   . VAL D 1 543 ? 147.442 147.162 146.975 1.00 21.26  ? 543 VAL D N   1 
ATOM   18406 C CA  . VAL D 1 543 ? 146.217 147.908 147.294 1.00 19.67  ? 543 VAL D CA  1 
ATOM   18407 C C   . VAL D 1 543 ? 145.630 147.467 148.631 1.00 21.93  ? 543 VAL D C   1 
ATOM   18408 O O   . VAL D 1 543 ? 145.307 148.302 149.473 1.00 30.93  ? 543 VAL D O   1 
ATOM   18409 C CB  . VAL D 1 543 ? 145.172 147.774 146.170 1.00 22.11  ? 543 VAL D CB  1 
ATOM   18410 C CG1 . VAL D 1 543 ? 143.926 148.606 146.459 1.00 20.68  ? 543 VAL D CG1 1 
ATOM   18411 C CG2 . VAL D 1 543 ? 145.757 148.244 144.840 1.00 24.61  ? 543 VAL D CG2 1 
ATOM   18412 N N   . TYR D 1 544 ? 145.544 146.158 148.857 1.00 29.66  ? 544 TYR D N   1 
ATOM   18413 C CA  . TYR D 1 544 ? 145.032 145.593 150.091 1.00 11.40  ? 544 TYR D CA  1 
ATOM   18414 C C   . TYR D 1 544 ? 145.855 145.987 151.325 1.00 14.48  ? 544 TYR D C   1 
ATOM   18415 O O   . TYR D 1 544 ? 145.276 146.319 152.350 1.00 29.68  ? 544 TYR D O   1 
ATOM   18416 C CB  . TYR D 1 544 ? 144.890 144.074 149.971 1.00 19.05  ? 544 TYR D CB  1 
ATOM   18417 C CG  . TYR D 1 544 ? 144.416 143.449 151.255 1.00 30.63  ? 544 TYR D CG  1 
ATOM   18418 C CD1 . TYR D 1 544 ? 143.083 143.505 151.618 1.00 25.03  ? 544 TYR D CD1 1 
ATOM   18419 C CD2 . TYR D 1 544 ? 145.307 142.865 152.136 1.00 23.56  ? 544 TYR D CD2 1 
ATOM   18420 C CE1 . TYR D 1 544 ? 142.641 142.970 152.813 1.00 22.27  ? 544 TYR D CE1 1 
ATOM   18421 C CE2 . TYR D 1 544 ? 144.882 142.329 153.338 1.00 16.54  ? 544 TYR D CE2 1 
ATOM   18422 C CZ  . TYR D 1 544 ? 143.544 142.376 153.673 1.00 28.73  ? 544 TYR D CZ  1 
ATOM   18423 O OH  . TYR D 1 544 ? 143.114 141.842 154.849 1.00 39.08  ? 544 TYR D OH  1 
ATOM   18424 N N   . LEU D 1 545 ? 147.186 145.992 151.259 1.00 10.84  ? 545 LEU D N   1 
ATOM   18425 C CA  . LEU D 1 545 ? 148.025 146.378 152.394 1.00 16.93  ? 545 LEU D CA  1 
ATOM   18426 C C   . LEU D 1 545 ? 147.954 147.873 152.699 1.00 17.13  ? 545 LEU D C   1 
ATOM   18427 O O   . LEU D 1 545 ? 148.029 148.257 153.861 1.00 27.95  ? 545 LEU D O   1 
ATOM   18428 C CB  . LEU D 1 545 ? 149.472 145.928 152.164 1.00 24.28  ? 545 LEU D CB  1 
ATOM   18429 C CG  . LEU D 1 545 ? 149.701 144.408 152.237 1.00 26.90  ? 545 LEU D CG  1 
ATOM   18430 C CD1 . LEU D 1 545 ? 151.182 144.135 152.003 1.00 26.33  ? 545 LEU D CD1 1 
ATOM   18431 C CD2 . LEU D 1 545 ? 149.306 143.795 153.576 1.00 18.91  ? 545 LEU D CD2 1 
ATOM   18432 N N   . VAL D 1 546 ? 147.746 148.730 151.700 1.00 26.76  ? 546 VAL D N   1 
ATOM   18433 C CA  . VAL D 1 546 ? 147.457 150.151 151.932 1.00 17.52  ? 546 VAL D CA  1 
ATOM   18434 C C   . VAL D 1 546 ? 146.115 150.333 152.644 1.00 24.60  ? 546 VAL D C   1 
ATOM   18435 O O   . VAL D 1 546 ? 146.051 151.096 153.603 1.00 32.21  ? 546 VAL D O   1 
ATOM   18436 C CB  . VAL D 1 546 ? 147.540 150.952 150.622 1.00 22.01  ? 546 VAL D CB  1 
ATOM   18437 C CG1 . VAL D 1 546 ? 147.043 152.387 150.785 1.00 19.88  ? 546 VAL D CG1 1 
ATOM   18438 C CG2 . VAL D 1 546 ? 148.991 151.028 150.147 1.00 21.98  ? 546 VAL D CG2 1 
ATOM   18439 N N   . PHE D 1 547 ? 145.066 149.606 152.246 1.00 26.33  ? 547 PHE D N   1 
ATOM   18440 C CA  . PHE D 1 547 ? 143.778 149.655 152.988 1.00 13.54  ? 547 PHE D CA  1 
ATOM   18441 C C   . PHE D 1 547 ? 143.989 149.104 154.403 1.00 18.12  ? 547 PHE D C   1 
ATOM   18442 O O   . PHE D 1 547 ? 143.606 149.778 155.350 1.00 34.33  ? 547 PHE D O   1 
ATOM   18443 C CB  . PHE D 1 547 ? 142.695 148.874 152.238 1.00 18.05  ? 547 PHE D CB  1 
ATOM   18444 C CG  . PHE D 1 547 ? 142.061 149.614 151.086 1.00 23.53  ? 547 PHE D CG  1 
ATOM   18445 C CD1 . PHE D 1 547 ? 142.736 149.771 149.887 1.00 30.28  ? 547 PHE D CD1 1 
ATOM   18446 C CD2 . PHE D 1 547 ? 140.788 150.148 151.201 1.00 34.62  ? 547 PHE D CD2 1 
ATOM   18447 C CE1 . PHE D 1 547 ? 142.153 150.452 148.828 1.00 29.57  ? 547 PHE D CE1 1 
ATOM   18448 C CE2 . PHE D 1 547 ? 140.206 150.826 150.142 1.00 30.59  ? 547 PHE D CE2 1 
ATOM   18449 C CZ  . PHE D 1 547 ? 140.889 150.977 148.958 1.00 24.93  ? 547 PHE D CZ  1 
ATOM   18450 N N   . LEU D 1 548 ? 144.620 147.943 154.570 1.00 25.17  ? 548 LEU D N   1 
ATOM   18451 C CA  . LEU D 1 548 ? 144.863 147.312 155.858 1.00 16.53  ? 548 LEU D CA  1 
ATOM   18452 C C   . LEU D 1 548 ? 145.598 148.239 156.820 1.00 15.31  ? 548 LEU D C   1 
ATOM   18453 O O   . LEU D 1 548 ? 145.099 148.518 157.904 1.00 33.86  ? 548 LEU D O   1 
ATOM   18454 C CB  . LEU D 1 548 ? 145.642 146.009 155.626 1.00 26.07  ? 548 LEU D CB  1 
ATOM   18455 C CG  . LEU D 1 548 ? 145.903 145.205 156.907 1.00 29.16  ? 548 LEU D CG  1 
ATOM   18456 C CD1 . LEU D 1 548 ? 144.603 144.619 157.436 1.00 22.31  ? 548 LEU D CD1 1 
ATOM   18457 C CD2 . LEU D 1 548 ? 146.880 144.075 156.622 1.00 26.04  ? 548 LEU D CD2 1 
ATOM   18458 N N   . PHE D 1 549 ? 146.769 148.747 156.447 1.00 20.69  ? 549 PHE D N   1 
ATOM   18459 C CA  . PHE D 1 549 ? 147.563 149.564 157.350 1.00 22.94  ? 549 PHE D CA  1 
ATOM   18460 C C   . PHE D 1 549 ? 147.002 150.974 157.540 1.00 21.46  ? 549 PHE D C   1 
ATOM   18461 O O   . PHE D 1 549 ? 147.055 151.480 158.656 1.00 37.55  ? 549 PHE D O   1 
ATOM   18462 C CB  . PHE D 1 549 ? 149.033 149.547 156.921 1.00 23.52  ? 549 PHE D CB  1 
ATOM   18463 C CG  . PHE D 1 549 ? 149.652 148.156 156.896 1.00 32.21  ? 549 PHE D CG  1 
ATOM   18464 C CD1 . PHE D 1 549 ? 149.449 147.254 157.961 1.00 28.05  ? 549 PHE D CD1 1 
ATOM   18465 C CD2 . PHE D 1 549 ? 150.448 147.759 155.808 1.00 35.09  ? 549 PHE D CD2 1 
ATOM   18466 C CE1 . PHE D 1 549 ? 150.011 145.970 157.925 1.00 26.13  ? 549 PHE D CE1 1 
ATOM   18467 C CE2 . PHE D 1 549 ? 151.016 146.474 155.776 1.00 30.84  ? 549 PHE D CE2 1 
ATOM   18468 C CZ  . PHE D 1 549 ? 150.794 145.578 156.828 1.00 27.61  ? 549 PHE D CZ  1 
ATOM   18469 N N   . GLY D 1 550 ? 146.382 151.579 156.525 1.00 17.43  ? 550 GLY D N   1 
ATOM   18470 C CA  . GLY D 1 550 ? 145.690 152.858 156.657 1.00 14.65  ? 550 GLY D CA  1 
ATOM   18471 C C   . GLY D 1 550 ? 144.543 152.814 157.667 1.00 22.20  ? 550 GLY D C   1 
ATOM   18472 O O   . GLY D 1 550 ? 144.465 153.672 158.543 1.00 32.42  ? 550 GLY D O   1 
ATOM   18473 N N   . PHE D 1 551 ? 143.683 151.792 157.613 1.00 19.87  ? 551 PHE D N   1 
ATOM   18474 C CA  . PHE D 1 551 ? 142.637 151.608 158.615 1.00 11.81  ? 551 PHE D CA  1 
ATOM   18475 C C   . PHE D 1 551 ? 143.173 151.098 159.963 1.00 15.32  ? 551 PHE D C   1 
ATOM   18476 O O   . PHE D 1 551 ? 142.631 151.475 160.995 1.00 26.23  ? 551 PHE D O   1 
ATOM   18477 C CB  . PHE D 1 551 ? 141.521 150.720 158.056 1.00 10.67  ? 551 PHE D CB  1 
ATOM   18478 C CG  . PHE D 1 551 ? 140.539 151.447 157.161 1.00 12.88  ? 551 PHE D CG  1 
ATOM   18479 C CD1 . PHE D 1 551 ? 139.425 152.089 157.728 1.00 12.08  ? 551 PHE D CD1 1 
ATOM   18480 C CD2 . PHE D 1 551 ? 140.693 151.456 155.762 1.00 11.13  ? 551 PHE D CD2 1 
ATOM   18481 C CE1 . PHE D 1 551 ? 138.474 152.714 156.912 1.00 12.39  ? 551 PHE D CE1 1 
ATOM   18482 C CE2 . PHE D 1 551 ? 139.742 152.072 154.946 1.00 7.38   ? 551 PHE D CE2 1 
ATOM   18483 C CZ  . PHE D 1 551 ? 138.624 152.700 155.518 1.00 17.30  ? 551 PHE D CZ  1 
ATOM   18484 N N   . ALA D 1 552 ? 144.252 150.314 160.013 1.00 21.79  ? 552 ALA D N   1 
ATOM   18485 C CA  . ALA D 1 552 ? 144.854 149.894 161.273 1.00 18.96  ? 552 ALA D CA  1 
ATOM   18486 C C   . ALA D 1 552 ? 145.421 151.070 162.086 1.00 24.72  ? 552 ALA D C   1 
ATOM   18487 O O   . ALA D 1 552 ? 145.113 151.180 163.269 1.00 32.93  ? 552 ALA D O   1 
ATOM   18488 C CB  . ALA D 1 552 ? 145.928 148.837 161.008 1.00 20.55  ? 552 ALA D CB  1 
ATOM   18489 N N   . VAL D 1 553 ? 146.196 151.985 161.484 1.00 27.90  ? 553 VAL D N   1 
ATOM   18490 C CA  . VAL D 1 553 ? 146.705 153.170 162.203 1.00 23.67  ? 553 VAL D CA  1 
ATOM   18491 C C   . VAL D 1 553 ? 145.567 154.060 162.693 1.00 21.27  ? 553 VAL D C   1 
ATOM   18492 O O   . VAL D 1 553 ? 145.623 154.572 163.807 1.00 25.54  ? 553 VAL D O   1 
ATOM   18493 C CB  . VAL D 1 553 ? 147.743 153.986 161.396 1.00 23.54  ? 553 VAL D CB  1 
ATOM   18494 C CG1 . VAL D 1 553 ? 148.992 153.165 161.088 1.00 23.23  ? 553 VAL D CG1 1 
ATOM   18495 C CG2 . VAL D 1 553 ? 147.244 154.593 160.084 1.00 22.05  ? 553 VAL D CG2 1 
ATOM   18496 N N   . ALA D 1 554 ? 144.502 154.190 161.908 1.00 22.00  ? 554 ALA D N   1 
ATOM   18497 C CA  . ALA D 1 554 ? 143.314 154.954 162.256 1.00 17.02  ? 554 ALA D CA  1 
ATOM   18498 C C   . ALA D 1 554 ? 142.525 154.369 163.435 1.00 22.95  ? 554 ALA D C   1 
ATOM   18499 O O   . ALA D 1 554 ? 142.225 155.096 164.381 1.00 27.73  ? 554 ALA D O   1 
ATOM   18500 C CB  . ALA D 1 554 ? 142.465 155.046 160.999 1.00 17.90  ? 554 ALA D CB  1 
ATOM   18501 N N   . LEU D 1 555 ? 142.238 153.064 163.434 1.00 30.11  ? 555 LEU D N   1 
ATOM   18502 C CA  . LEU D 1 555 ? 141.556 152.393 164.542 1.00 24.47  ? 555 LEU D CA  1 
ATOM   18503 C C   . LEU D 1 555 ? 142.356 152.435 165.838 1.00 25.43  ? 555 LEU D C   1 
ATOM   18504 O O   . LEU D 1 555 ? 141.783 152.725 166.883 1.00 30.90  ? 555 LEU D O   1 
ATOM   18505 C CB  . LEU D 1 555 ? 141.239 150.936 164.174 1.00 26.90  ? 555 LEU D CB  1 
ATOM   18506 C CG  . LEU D 1 555 ? 140.108 150.796 163.149 1.00 28.28  ? 555 LEU D CG  1 
ATOM   18507 C CD1 . LEU D 1 555 ? 140.014 149.341 162.726 1.00 32.03  ? 555 LEU D CD1 1 
ATOM   18508 C CD2 . LEU D 1 555 ? 138.749 151.197 163.711 1.00 27.83  ? 555 LEU D CD2 1 
ATOM   18509 N N   . VAL D 1 556 ? 143.669 152.209 165.795 1.00 22.70  ? 556 VAL D N   1 
ATOM   18510 C CA  . VAL D 1 556 ? 144.517 152.309 166.989 1.00 27.39  ? 556 VAL D CA  1 
ATOM   18511 C C   . VAL D 1 556 ? 144.511 153.722 167.558 1.00 29.23  ? 556 VAL D C   1 
ATOM   18512 O O   . VAL D 1 556 ? 144.305 153.895 168.753 1.00 34.43  ? 556 VAL D O   1 
ATOM   18513 C CB  . VAL D 1 556 ? 145.948 151.834 166.697 1.00 27.41  ? 556 VAL D CB  1 
ATOM   18514 C CG1 . VAL D 1 556 ? 146.905 152.058 167.866 1.00 27.23  ? 556 VAL D CG1 1 
ATOM   18515 C CG2 . VAL D 1 556 ? 145.934 150.340 166.410 1.00 29.29  ? 556 VAL D CG2 1 
ATOM   18516 N N   . SER D 1 557 ? 144.662 154.740 166.710 1.00 35.18  ? 557 SER D N   1 
ATOM   18517 C CA  . SER D 1 557 ? 144.660 156.147 167.127 1.00 27.01  ? 557 SER D CA  1 
ATOM   18518 C C   . SER D 1 557 ? 143.341 156.573 167.774 1.00 30.70  ? 557 SER D C   1 
ATOM   18519 O O   . SER D 1 557 ? 143.340 157.258 168.791 1.00 36.43  ? 557 SER D O   1 
ATOM   18520 C CB  . SER D 1 557 ? 144.945 157.056 165.930 1.00 25.48  ? 557 SER D CB  1 
ATOM   18521 O OG  . SER D 1 557 ? 146.167 156.703 165.317 1.00 35.32  ? 557 SER D OG  1 
ATOM   18522 N N   . LEU D 1 558 ? 142.208 156.153 167.207 1.00 30.28  ? 558 LEU D N   1 
ATOM   18523 C CA  . LEU D 1 558 ? 140.887 156.562 167.663 1.00 28.12  ? 558 LEU D CA  1 
ATOM   18524 C C   . LEU D 1 558 ? 140.386 155.780 168.892 1.00 36.05  ? 558 LEU D C   1 
ATOM   18525 O O   . LEU D 1 558 ? 139.610 156.300 169.684 1.00 40.88  ? 558 LEU D O   1 
ATOM   18526 C CB  . LEU D 1 558 ? 139.937 156.459 166.462 1.00 22.27  ? 558 LEU D CB  1 
ATOM   18527 C CG  . LEU D 1 558 ? 138.622 157.226 166.627 1.00 29.64  ? 558 LEU D CG  1 
ATOM   18528 C CD1 . LEU D 1 558 ? 138.821 158.734 166.784 1.00 31.65  ? 558 LEU D CD1 1 
ATOM   18529 C CD2 . LEU D 1 558 ? 137.774 157.017 165.385 1.00 30.92  ? 558 LEU D CD2 1 
ATOM   18530 N N   . SER D 1 559 ? 140.871 154.556 169.103 1.00 41.73  ? 559 SER D N   1 
ATOM   18531 C CA  . SER D 1 559 ? 140.504 153.698 170.242 1.00 35.44  ? 559 SER D CA  1 
ATOM   18532 C C   . SER D 1 559 ? 141.271 153.995 171.540 1.00 42.84  ? 559 SER D C   1 
ATOM   18533 O O   . SER D 1 559 ? 141.046 153.327 172.548 1.00 50.01  ? 559 SER D O   1 
ATOM   18534 C CB  . SER D 1 559 ? 140.681 152.225 169.875 1.00 38.85  ? 559 SER D CB  1 
ATOM   18535 O OG  . SER D 1 559 ? 140.004 151.949 168.671 1.00 42.50  ? 559 SER D OG  1 
ATOM   18536 N N   . ARG D 1 560 ? 142.172 154.982 171.557 1.00 46.05  ? 560 ARG D N   1 
ATOM   18537 C CA  . ARG D 1 560 ? 142.932 155.390 172.756 1.00 46.31  ? 560 ARG D CA  1 
ATOM   18538 C C   . ARG D 1 560 ? 142.060 155.945 173.883 1.00 50.34  ? 560 ARG D C   1 
ATOM   18539 O O   . ARG D 1 560 ? 142.454 155.894 175.044 1.00 53.44  ? 560 ARG D O   1 
ATOM   18540 C CB  . ARG D 1 560 ? 143.945 156.477 172.375 1.00 46.41  ? 560 ARG D CB  1 
ATOM   18541 C CG  . ARG D 1 560 ? 145.087 155.986 171.491 1.00 44.38  ? 560 ARG D CG  1 
ATOM   18542 C CD  . ARG D 1 560 ? 146.107 155.157 172.272 1.00 47.20  ? 560 ARG D CD  1 
ATOM   18543 N NE  . ARG D 1 560 ? 147.122 154.544 171.396 1.00 52.18  ? 560 ARG D NE  1 
ATOM   18544 C CZ  . ARG D 1 560 ? 148.031 155.158 170.670 1.00 48.53  ? 560 ARG D CZ  1 
ATOM   18545 N NH1 . ARG D 1 560 ? 148.905 154.476 169.995 1.00 46.96  ? 560 ARG D NH1 1 
ATOM   18546 N NH2 . ARG D 1 560 ? 148.109 156.452 170.613 1.00 47.72  ? 560 ARG D NH2 1 
ATOM   18547 N N   . GLU D 1 561 ? 140.901 156.499 173.543 1.00 52.51  ? 561 GLU D N   1 
ATOM   18548 C CA  . GLU D 1 561 ? 140.015 157.190 174.473 1.00 54.27  ? 561 GLU D CA  1 
ATOM   18549 C C   . GLU D 1 561 ? 138.838 156.313 174.913 1.00 58.06  ? 561 GLU D C   1 
ATOM   18550 O O   . GLU D 1 561 ? 138.055 155.839 174.092 1.00 56.00  ? 561 GLU D O   1 
ATOM   18551 C CB  . GLU D 1 561 ? 139.495 158.474 173.803 1.00 55.99  ? 561 GLU D CB  1 
ATOM   18552 C CG  . GLU D 1 561 ? 140.556 159.574 173.642 1.00 57.52  ? 561 GLU D CG  1 
ATOM   18553 C CD  . GLU D 1 561 ? 141.140 160.060 174.978 1.00 60.26  ? 561 GLU D CD  1 
ATOM   18554 O OE1 . GLU D 1 561 ? 140.453 159.958 176.019 1.00 60.36  ? 561 GLU D OE1 1 
ATOM   18555 O OE2 . GLU D 1 561 ? 142.287 160.558 174.979 1.00 60.18  ? 561 GLU D OE2 1 
ATOM   18556 N N   . ALA D 1 562 ? 138.679 156.120 176.225 1.00 61.93  ? 562 ALA D N   1 
ATOM   18557 C CA  . ALA D 1 562 ? 137.549 155.417 176.820 1.00 60.80  ? 562 ALA D CA  1 
ATOM   18558 C C   . ALA D 1 562 ? 136.352 156.347 177.120 1.00 59.90  ? 562 ALA D C   1 
ATOM   18559 O O   . ALA D 1 562 ? 136.521 157.553 177.298 1.00 62.46  ? 562 ALA D O   1 
ATOM   18560 C CB  . ALA D 1 562 ? 138.044 154.701 178.076 1.00 59.37  ? 562 ALA D CB  1 
ATOM   18561 N N   . ARG D 1 563 ? 135.147 155.788 177.220 1.00 59.73  ? 563 ARG D N   1 
ATOM   18562 C CA  . ARG D 1 563 ? 133.924 156.501 177.606 1.00 62.22  ? 563 ARG D CA  1 
ATOM   18563 C C   . ARG D 1 563 ? 132.901 155.596 178.304 1.00 64.54  ? 563 ARG D C   1 
ATOM   18564 O O   . ARG D 1 563 ? 132.820 154.393 178.042 1.00 64.27  ? 563 ARG D O   1 
ATOM   18565 C CB  . ARG D 1 563 ? 133.282 157.136 176.376 1.00 59.90  ? 563 ARG D CB  1 
ATOM   18566 N N   . PRO D 1 589 ? 141.112 145.590 171.890 1.00 54.87  ? 589 PRO D N   1 
ATOM   18567 C CA  . PRO D 1 589 ? 140.758 146.997 172.018 1.00 54.32  ? 589 PRO D CA  1 
ATOM   18568 C C   . PRO D 1 589 ? 141.438 147.913 170.991 1.00 51.55  ? 589 PRO D C   1 
ATOM   18569 O O   . PRO D 1 589 ? 141.473 149.126 171.184 1.00 53.95  ? 589 PRO D O   1 
ATOM   18570 C CB  . PRO D 1 589 ? 141.125 147.369 173.459 1.00 50.66  ? 589 PRO D CB  1 
ATOM   18571 C CG  . PRO D 1 589 ? 141.030 146.047 174.209 1.00 48.34  ? 589 PRO D CG  1 
ATOM   18572 C CD  . PRO D 1 589 ? 141.519 145.047 173.167 1.00 52.58  ? 589 PRO D CD  1 
ATOM   18573 N N   . TYR D 1 590 ? 142.032 147.341 169.938 1.00 40.57  ? 590 TYR D N   1 
ATOM   18574 C CA  . TYR D 1 590 ? 142.939 148.005 168.989 1.00 37.04  ? 590 TYR D CA  1 
ATOM   18575 C C   . TYR D 1 590 ? 144.141 148.645 169.704 1.00 39.51  ? 590 TYR D C   1 
ATOM   18576 O O   . TYR D 1 590 ? 144.387 149.844 169.608 1.00 43.89  ? 590 TYR D O   1 
ATOM   18577 C CB  . TYR D 1 590 ? 142.182 148.962 168.054 1.00 36.79  ? 590 TYR D CB  1 
ATOM   18578 C CG  . TYR D 1 590 ? 140.983 148.332 167.382 1.00 36.66  ? 590 TYR D CG  1 
ATOM   18579 C CD1 . TYR D 1 590 ? 141.185 147.306 166.445 1.00 38.44  ? 590 TYR D CD1 1 
ATOM   18580 C CD2 . TYR D 1 590 ? 139.675 148.715 167.727 1.00 38.44  ? 590 TYR D CD2 1 
ATOM   18581 C CE1 . TYR D 1 590 ? 140.093 146.658 165.854 1.00 35.87  ? 590 TYR D CE1 1 
ATOM   18582 C CE2 . TYR D 1 590 ? 138.575 148.061 167.148 1.00 40.32  ? 590 TYR D CE2 1 
ATOM   18583 C CZ  . TYR D 1 590 ? 138.784 147.026 166.216 1.00 39.25  ? 590 TYR D CZ  1 
ATOM   18584 O OH  . TYR D 1 590 ? 137.735 146.351 165.690 1.00 47.47  ? 590 TYR D OH  1 
ATOM   18585 N N   . ARG D 1 591 ? 144.879 147.850 170.476 1.00 39.79  ? 591 ARG D N   1 
ATOM   18586 C CA  . ARG D 1 591 ? 145.949 148.341 171.347 1.00 40.13  ? 591 ARG D CA  1 
ATOM   18587 C C   . ARG D 1 591 ? 147.283 148.610 170.631 1.00 39.55  ? 591 ARG D C   1 
ATOM   18588 O O   . ARG D 1 591 ? 148.106 149.382 171.119 1.00 44.83  ? 591 ARG D O   1 
ATOM   18589 C CB  . ARG D 1 591 ? 146.151 147.313 172.453 1.00 39.14  ? 591 ARG D CB  1 
ATOM   18590 N N   . SER D 1 592 ? 147.517 147.990 169.477 1.00 32.75  ? 592 SER D N   1 
ATOM   18591 C CA  . SER D 1 592 ? 148.752 148.078 168.695 1.00 32.74  ? 592 SER D CA  1 
ATOM   18592 C C   . SER D 1 592 ? 148.466 147.902 167.207 1.00 33.88  ? 592 SER D C   1 
ATOM   18593 O O   . SER D 1 592 ? 147.384 147.455 166.828 1.00 39.31  ? 592 SER D O   1 
ATOM   18594 C CB  . SER D 1 592 ? 149.783 147.055 169.197 1.00 40.07  ? 592 SER D CB  1 
ATOM   18595 O OG  . SER D 1 592 ? 149.450 145.729 168.830 1.00 40.96  ? 592 SER D OG  1 
ATOM   18596 N N   . ILE D 1 593 ? 149.410 148.264 166.332 1.00 32.70  ? 593 ILE D N   1 
ATOM   18597 C CA  . ILE D 1 593 ? 149.239 148.097 164.883 1.00 27.61  ? 593 ILE D CA  1 
ATOM   18598 C C   . ILE D 1 593 ? 149.117 146.618 164.506 1.00 33.02  ? 593 ILE D C   1 
ATOM   18599 O O   . ILE D 1 593 ? 148.306 146.295 163.644 1.00 37.29  ? 593 ILE D O   1 
ATOM   18600 C CB  . ILE D 1 593 ? 150.367 148.800 164.093 1.00 33.30  ? 593 ILE D CB  1 
ATOM   18601 C CG1 . ILE D 1 593 ? 150.439 150.313 164.370 1.00 34.25  ? 593 ILE D CG1 1 
ATOM   18602 C CG2 . ILE D 1 593 ? 150.239 148.566 162.576 1.00 29.16  ? 593 ILE D CG2 1 
ATOM   18603 C CD1 . ILE D 1 593 ? 149.172 151.095 164.036 1.00 34.18  ? 593 ILE D CD1 1 
ATOM   18604 N N   . LEU D 1 594 ? 149.840 145.703 165.161 1.00 36.49  ? 594 LEU D N   1 
ATOM   18605 C CA  . LEU D 1 594 ? 149.700 144.260 164.928 1.00 31.29  ? 594 LEU D CA  1 
ATOM   18606 C C   . LEU D 1 594 ? 148.312 143.759 165.344 1.00 30.72  ? 594 LEU D C   1 
ATOM   18607 O O   . LEU D 1 594 ? 147.666 143.057 164.579 1.00 37.09  ? 594 LEU D O   1 
ATOM   18608 C CB  . LEU D 1 594 ? 150.829 143.500 165.648 1.00 38.53  ? 594 LEU D CB  1 
ATOM   18609 C CG  . LEU D 1 594 ? 150.733 141.961 165.551 1.00 41.12  ? 594 LEU D CG  1 
ATOM   18610 C CD1 . LEU D 1 594 ? 150.818 141.458 164.114 1.00 38.84  ? 594 LEU D CD1 1 
ATOM   18611 C CD2 . LEU D 1 594 ? 151.859 141.316 166.343 1.00 35.80  ? 594 LEU D CD2 1 
ATOM   18612 N N   . ASP D 1 595 ? 147.828 144.171 166.515 1.00 27.66  ? 595 ASP D N   1 
ATOM   18613 C CA  . ASP D 1 595 ? 146.495 143.836 167.009 1.00 27.82  ? 595 ASP D CA  1 
ATOM   18614 C C   . ASP D 1 595 ? 145.400 144.287 166.028 1.00 31.34  ? 595 ASP D C   1 
ATOM   18615 O O   . ASP D 1 595 ? 144.611 143.472 165.559 1.00 36.15  ? 595 ASP D O   1 
ATOM   18616 C CB  . ASP D 1 595 ? 146.326 144.487 168.391 1.00 33.90  ? 595 ASP D CB  1 
ATOM   18617 C CG  . ASP D 1 595 ? 144.988 144.205 169.070 1.00 42.60  ? 595 ASP D CG  1 
ATOM   18618 O OD1 . ASP D 1 595 ? 144.530 143.045 169.049 1.00 43.02  ? 595 ASP D OD1 1 
ATOM   18619 O OD2 . ASP D 1 595 ? 144.431 145.150 169.672 1.00 43.44  ? 595 ASP D OD2 1 
ATOM   18620 N N   . ALA D 1 596 ? 145.395 145.560 165.632 1.00 30.10  ? 596 ALA D N   1 
ATOM   18621 C CA  . ALA D 1 596 ? 144.418 146.088 164.692 1.00 19.23  ? 596 ALA D CA  1 
ATOM   18622 C C   . ALA D 1 596 ? 144.556 145.522 163.275 1.00 24.64  ? 596 ALA D C   1 
ATOM   18623 O O   . ALA D 1 596 ? 143.550 145.273 162.627 1.00 31.15  ? 596 ALA D O   1 
ATOM   18624 C CB  . ALA D 1 596 ? 144.511 147.613 164.702 1.00 24.65  ? 596 ALA D CB  1 
ATOM   18625 N N   . SER D 1 597 ? 145.773 145.259 162.792 1.00 28.40  ? 597 SER D N   1 
ATOM   18626 C CA  . SER D 1 597 ? 145.980 144.606 161.493 1.00 19.72  ? 597 SER D CA  1 
ATOM   18627 C C   . SER D 1 597 ? 145.411 143.196 161.477 1.00 21.65  ? 597 SER D C   1 
ATOM   18628 O O   . SER D 1 597 ? 144.827 142.790 160.484 1.00 30.35  ? 597 SER D O   1 
ATOM   18629 C CB  . SER D 1 597 ? 147.458 144.507 161.131 1.00 23.46  ? 597 SER D CB  1 
ATOM   18630 O OG  . SER D 1 597 ? 148.030 145.785 161.056 1.00 35.54  ? 597 SER D OG  1 
ATOM   18631 N N   . LEU D 1 598 ? 145.565 142.438 162.557 1.00 22.32  ? 598 LEU D N   1 
ATOM   18632 C CA  . LEU D 1 598 ? 145.054 141.078 162.626 1.00 21.00  ? 598 LEU D CA  1 
ATOM   18633 C C   . LEU D 1 598 ? 143.524 141.055 162.743 1.00 19.07  ? 598 LEU D C   1 
ATOM   18634 O O   . LEU D 1 598 ? 142.870 140.280 162.054 1.00 24.35  ? 598 LEU D O   1 
ATOM   18635 C CB  . LEU D 1 598 ? 145.785 140.343 163.757 1.00 26.83  ? 598 LEU D CB  1 
ATOM   18636 C CG  . LEU D 1 598 ? 145.658 138.819 163.671 1.00 30.36  ? 598 LEU D CG  1 
ATOM   18637 C CD1 . LEU D 1 598 ? 146.394 138.274 162.448 1.00 20.74  ? 598 LEU D CD1 1 
ATOM   18638 C CD2 . LEU D 1 598 ? 146.252 138.193 164.925 1.00 22.68  ? 598 LEU D CD2 1 
ATOM   18639 N N   . GLU D 1 599 ? 142.929 141.953 163.527 1.00 21.27  ? 599 GLU D N   1 
ATOM   18640 C CA  . GLU D 1 599 ? 141.477 142.147 163.562 1.00 14.57  ? 599 GLU D CA  1 
ATOM   18641 C C   . GLU D 1 599 ? 140.891 142.579 162.215 1.00 21.83  ? 599 GLU D C   1 
ATOM   18642 O O   . GLU D 1 599 ? 139.869 142.044 161.791 1.00 33.85  ? 599 GLU D O   1 
ATOM   18643 C CB  . GLU D 1 599 ? 141.106 143.181 164.636 1.00 25.85  ? 599 GLU D CB  1 
ATOM   18644 C CG  . GLU D 1 599 ? 141.302 142.702 166.080 1.00 24.81  ? 599 GLU D CG  1 
ATOM   18645 C CD  . GLU D 1 599 ? 140.605 141.372 166.389 1.00 36.56  ? 599 GLU D CD  1 
ATOM   18646 O OE1 . GLU D 1 599 ? 139.461 141.164 165.937 1.00 36.58  ? 599 GLU D OE1 1 
ATOM   18647 O OE2 . GLU D 1 599 ? 141.206 140.505 167.059 1.00 37.37  ? 599 GLU D OE2 1 
ATOM   18648 N N   . LEU D 1 600 ? 141.538 143.491 161.492 1.00 23.09  ? 600 LEU D N   1 
ATOM   18649 C CA  . LEU D 1 600 ? 141.123 143.863 160.146 1.00 7.60   ? 600 LEU D CA  1 
ATOM   18650 C C   . LEU D 1 600 ? 141.323 142.743 159.126 1.00 7.70   ? 600 LEU D C   1 
ATOM   18651 O O   . LEU D 1 600 ? 140.498 142.578 158.228 1.00 27.63  ? 600 LEU D O   1 
ATOM   18652 C CB  . LEU D 1 600 ? 141.878 145.116 159.698 1.00 20.99  ? 600 LEU D CB  1 
ATOM   18653 C CG  . LEU D 1 600 ? 141.430 146.424 160.358 1.00 7.03   ? 600 LEU D CG  1 
ATOM   18654 C CD1 . LEU D 1 600 ? 142.199 147.563 159.722 1.00 14.06  ? 600 LEU D CD1 1 
ATOM   18655 C CD2 . LEU D 1 600 ? 139.949 146.689 160.165 1.00 13.98  ? 600 LEU D CD2 1 
ATOM   18656 N N   . PHE D 1 601 ? 142.389 141.956 159.226 1.00 18.83  ? 601 PHE D N   1 
ATOM   18657 C CA  . PHE D 1 601 ? 142.615 140.822 158.341 1.00 16.41  ? 601 PHE D CA  1 
ATOM   18658 C C   . PHE D 1 601 ? 141.568 139.711 158.533 1.00 16.51  ? 601 PHE D C   1 
ATOM   18659 O O   . PHE D 1 601 ? 141.132 139.095 157.562 1.00 14.51  ? 601 PHE D O   1 
ATOM   18660 C CB  . PHE D 1 601 ? 144.047 140.306 158.519 1.00 14.10  ? 601 PHE D CB  1 
ATOM   18661 C CG  . PHE D 1 601 ? 144.365 139.167 157.577 1.00 17.13  ? 601 PHE D CG  1 
ATOM   18662 C CD1 . PHE D 1 601 ? 144.493 139.416 156.199 1.00 19.85  ? 601 PHE D CD1 1 
ATOM   18663 C CD2 . PHE D 1 601 ? 144.442 137.851 158.055 1.00 15.76  ? 601 PHE D CD2 1 
ATOM   18664 C CE1 . PHE D 1 601 ? 144.675 138.356 155.304 1.00 18.40  ? 601 PHE D CE1 1 
ATOM   18665 C CE2 . PHE D 1 601 ? 144.634 136.791 157.160 1.00 19.77  ? 601 PHE D CE2 1 
ATOM   18666 C CZ  . PHE D 1 601 ? 144.747 137.040 155.786 1.00 18.40  ? 601 PHE D CZ  1 
ATOM   18667 N N   . LYS D 1 602 ? 141.075 139.511 159.761 1.00 22.08  ? 602 LYS D N   1 
ATOM   18668 C CA  . LYS D 1 602 ? 140.038 138.524 160.077 1.00 9.24   ? 602 LYS D CA  1 
ATOM   18669 C C   . LYS D 1 602 ? 138.744 138.668 159.280 1.00 11.40  ? 602 LYS D C   1 
ATOM   18670 O O   . LYS D 1 602 ? 138.104 137.660 159.003 1.00 26.61  ? 602 LYS D O   1 
ATOM   18671 C CB  . LYS D 1 602 ? 139.785 138.472 161.590 1.00 8.83   ? 602 LYS D CB  1 
ATOM   18672 C CG  . LYS D 1 602 ? 140.810 137.522 162.214 1.00 13.86  ? 602 LYS D CG  1 
ATOM   18673 C CD  . LYS D 1 602 ? 140.568 137.213 163.688 1.00 17.19  ? 602 LYS D CD  1 
ATOM   18674 C CE  . LYS D 1 602 ? 140.934 138.380 164.591 1.00 13.84  ? 602 LYS D CE  1 
ATOM   18675 N NZ  . LYS D 1 602 ? 140.990 137.960 166.009 1.00 27.33  ? 602 LYS D NZ  1 
ATOM   18676 N N   . PHE D 1 603 ? 138.386 139.854 158.802 1.00 19.17  ? 603 PHE D N   1 
ATOM   18677 C CA  . PHE D 1 603 ? 137.260 140.030 157.884 1.00 19.97  ? 603 PHE D CA  1 
ATOM   18678 C C   . PHE D 1 603 ? 137.420 139.289 156.552 1.00 22.43  ? 603 PHE D C   1 
ATOM   18679 O O   . PHE D 1 603 ? 136.432 138.840 155.984 1.00 30.66  ? 603 PHE D O   1 
ATOM   18680 C CB  . PHE D 1 603 ? 137.033 141.518 157.628 1.00 9.82   ? 603 PHE D CB  1 
ATOM   18681 C CG  . PHE D 1 603 ? 136.465 142.246 158.818 1.00 14.63  ? 603 PHE D CG  1 
ATOM   18682 C CD1 . PHE D 1 603 ? 135.079 142.237 159.040 1.00 15.60  ? 603 PHE D CD1 1 
ATOM   18683 C CD2 . PHE D 1 603 ? 137.304 142.916 159.719 1.00 10.91  ? 603 PHE D CD2 1 
ATOM   18684 C CE1 . PHE D 1 603 ? 134.553 142.893 160.156 1.00 14.42  ? 603 PHE D CE1 1 
ATOM   18685 C CE2 . PHE D 1 603 ? 136.773 143.574 160.835 1.00 12.25  ? 603 PHE D CE2 1 
ATOM   18686 C CZ  . PHE D 1 603 ? 135.392 143.563 161.057 1.00 16.30  ? 603 PHE D CZ  1 
ATOM   18687 N N   . THR D 1 604 ? 138.641 139.106 156.055 1.00 26.75  ? 604 THR D N   1 
ATOM   18688 C CA  . THR D 1 604 ? 138.890 138.403 154.787 1.00 15.06  ? 604 THR D CA  1 
ATOM   18689 C C   . THR D 1 604 ? 138.736 136.882 154.894 1.00 13.86  ? 604 THR D C   1 
ATOM   18690 O O   . THR D 1 604 ? 138.505 136.220 153.889 1.00 28.67  ? 604 THR D O   1 
ATOM   18691 C CB  . THR D 1 604 ? 140.271 138.744 154.213 1.00 26.86  ? 604 THR D CB  1 
ATOM   18692 O OG1 . THR D 1 604 ? 141.300 138.183 154.987 1.00 32.71  ? 604 THR D OG1 1 
ATOM   18693 C CG2 . THR D 1 604 ? 140.512 140.247 154.116 1.00 23.28  ? 604 THR D CG2 1 
ATOM   18694 N N   . ILE D 1 605 ? 138.819 136.327 156.104 1.00 17.95  ? 605 ILE D N   1 
ATOM   18695 C CA  . ILE D 1 605 ? 138.691 134.894 156.392 1.00 15.20  ? 605 ILE D CA  1 
ATOM   18696 C C   . ILE D 1 605 ? 137.346 134.529 157.047 1.00 15.06  ? 605 ILE D C   1 
ATOM   18697 O O   . ILE D 1 605 ? 137.178 133.430 157.560 1.00 26.29  ? 605 ILE D O   1 
ATOM   18698 C CB  . ILE D 1 605 ? 139.913 134.368 157.172 1.00 11.53  ? 605 ILE D CB  1 
ATOM   18699 C CG1 . ILE D 1 605 ? 140.055 135.018 158.555 1.00 14.17  ? 605 ILE D CG1 1 
ATOM   18700 C CG2 . ILE D 1 605 ? 141.203 134.544 156.370 1.00 12.61  ? 605 ILE D CG2 1 
ATOM   18701 C CD1 . ILE D 1 605 ? 140.843 134.170 159.542 1.00 10.18  ? 605 ILE D CD1 1 
ATOM   18702 N N   . GLY D 1 606 ? 136.377 135.444 157.045 1.00 10.51  ? 606 GLY D N   1 
ATOM   18703 C CA  . GLY D 1 606 ? 135.047 135.224 157.607 1.00 0.00   ? 606 GLY D CA  1 
ATOM   18704 C C   . GLY D 1 606 ? 134.965 135.280 159.132 1.00 3.54   ? 606 GLY D C   1 
ATOM   18705 O O   . GLY D 1 606 ? 134.050 134.705 159.692 1.00 26.13  ? 606 GLY D O   1 
ATOM   18706 N N   . MET D 1 607 ? 135.900 135.951 159.807 1.00 15.85  ? 607 MET D N   1 
ATOM   18707 C CA  . MET D 1 607 ? 136.049 135.947 161.269 1.00 0.83   ? 607 MET D CA  1 
ATOM   18708 C C   . MET D 1 607 ? 136.065 137.335 161.926 1.00 13.35  ? 607 MET D C   1 
ATOM   18709 O O   . MET D 1 607 ? 136.407 137.460 163.097 1.00 15.20  ? 607 MET D O   1 
ATOM   18710 C CB  . MET D 1 607 ? 137.298 135.133 161.638 1.00 16.92  ? 607 MET D CB  1 
ATOM   18711 C CG  . MET D 1 607 ? 137.062 133.634 161.480 1.00 0.00   ? 607 MET D CG  1 
ATOM   18712 S SD  . MET D 1 607 ? 135.978 132.900 162.736 1.00 23.99  ? 607 MET D SD  1 
ATOM   18713 C CE  . MET D 1 607 ? 137.013 132.967 164.205 1.00 9.31   ? 607 MET D CE  1 
ATOM   18714 N N   . GLY D 1 608 ? 135.734 138.398 161.190 1.00 13.82  ? 608 GLY D N   1 
ATOM   18715 C CA  . GLY D 1 608 ? 135.841 139.776 161.665 1.00 5.67   ? 608 GLY D CA  1 
ATOM   18716 C C   . GLY D 1 608 ? 134.749 140.194 162.648 1.00 17.97  ? 608 GLY D C   1 
ATOM   18717 O O   . GLY D 1 608 ? 133.566 140.076 162.367 1.00 30.12  ? 608 GLY D O   1 
ATOM   18718 N N   . GLU D 1 609 ? 135.121 140.730 163.803 1.00 32.67  ? 609 GLU D N   1 
ATOM   18719 C CA  . GLU D 1 609 ? 134.160 141.211 164.797 1.00 28.62  ? 609 GLU D CA  1 
ATOM   18720 C C   . GLU D 1 609 ? 133.678 142.640 164.500 1.00 33.45  ? 609 GLU D C   1 
ATOM   18721 O O   . GLU D 1 609 ? 134.456 143.591 164.562 1.00 39.59  ? 609 GLU D O   1 
ATOM   18722 C CB  . GLU D 1 609 ? 134.764 141.111 166.204 1.00 31.73  ? 609 GLU D CB  1 
ATOM   18723 C CG  . GLU D 1 609 ? 134.953 139.667 166.699 1.00 36.83  ? 609 GLU D CG  1 
ATOM   18724 C CD  . GLU D 1 609 ? 133.650 138.940 167.082 1.00 47.46  ? 609 GLU D CD  1 
ATOM   18725 O OE1 . GLU D 1 609 ? 132.547 139.510 166.926 1.00 47.74  ? 609 GLU D OE1 1 
ATOM   18726 O OE2 . GLU D 1 609 ? 133.730 137.798 167.576 1.00 41.00  ? 609 GLU D OE2 1 
ATOM   18727 N N   . LEU D 1 610 ? 132.375 142.809 164.252 1.00 34.60  ? 610 LEU D N   1 
ATOM   18728 C CA  . LEU D 1 610 ? 131.689 144.104 164.303 1.00 27.87  ? 610 LEU D CA  1 
ATOM   18729 C C   . LEU D 1 610 ? 130.875 144.217 165.590 1.00 34.29  ? 610 LEU D C   1 
ATOM   18730 O O   . LEU D 1 610 ? 130.009 143.389 165.876 1.00 38.89  ? 610 LEU D O   1 
ATOM   18731 C CB  . LEU D 1 610 ? 130.723 144.295 163.127 1.00 28.23  ? 610 LEU D CB  1 
ATOM   18732 C CG  . LEU D 1 610 ? 131.356 144.398 161.746 1.00 32.26  ? 610 LEU D CG  1 
ATOM   18733 C CD1 . LEU D 1 610 ? 130.261 144.371 160.690 1.00 35.78  ? 610 LEU D CD1 1 
ATOM   18734 C CD2 . LEU D 1 610 ? 132.150 145.686 161.550 1.00 32.25  ? 610 LEU D CD2 1 
ATOM   18735 N N   . ALA D 1 611 ? 131.107 145.287 166.332 1.00 43.95  ? 611 ALA D N   1 
ATOM   18736 C CA  . ALA D 1 611 ? 130.324 145.647 167.499 1.00 42.09  ? 611 ALA D CA  1 
ATOM   18737 C C   . ALA D 1 611 ? 130.249 147.165 167.611 1.00 44.77  ? 611 ALA D C   1 
ATOM   18738 O O   . ALA D 1 611 ? 131.226 147.857 167.325 1.00 47.94  ? 611 ALA D O   1 
ATOM   18739 C CB  . ALA D 1 611 ? 130.982 145.023 168.732 1.00 39.91  ? 611 ALA D CB  1 
ATOM   18740 N N   . PHE D 1 612 ? 129.122 147.698 168.083 1.00 51.49  ? 612 PHE D N   1 
ATOM   18741 C CA  . PHE D 1 612 ? 129.080 149.049 168.629 1.00 49.69  ? 612 PHE D CA  1 
ATOM   18742 C C   . PHE D 1 612 ? 129.763 149.015 170.004 1.00 50.93  ? 612 PHE D C   1 
ATOM   18743 O O   . PHE D 1 612 ? 129.173 148.625 171.010 1.00 51.66  ? 612 PHE D O   1 
ATOM   18744 C CB  . PHE D 1 612 ? 127.629 149.531 168.654 1.00 49.42  ? 612 PHE D CB  1 
ATOM   18745 C CG  . PHE D 1 612 ? 127.471 150.987 169.023 1.00 52.15  ? 612 PHE D CG  1 
ATOM   18746 C CD1 . PHE D 1 612 ? 127.815 151.987 168.097 1.00 48.62  ? 612 PHE D CD1 1 
ATOM   18747 C CD2 . PHE D 1 612 ? 126.928 151.351 170.268 1.00 52.67  ? 612 PHE D CD2 1 
ATOM   18748 C CE1 . PHE D 1 612 ? 127.600 153.339 168.405 1.00 52.96  ? 612 PHE D CE1 1 
ATOM   18749 C CE2 . PHE D 1 612 ? 126.702 152.703 170.573 1.00 51.27  ? 612 PHE D CE2 1 
ATOM   18750 C CZ  . PHE D 1 612 ? 127.033 153.696 169.639 1.00 53.44  ? 612 PHE D CZ  1 
ATOM   18751 N N   . GLN D 1 613 ? 131.064 149.292 170.010 1.00 55.85  ? 613 GLN D N   1 
ATOM   18752 C CA  . GLN D 1 613 ? 131.978 148.940 171.096 1.00 56.87  ? 613 GLN D CA  1 
ATOM   18753 C C   . GLN D 1 613 ? 131.896 149.938 172.261 1.00 58.17  ? 613 GLN D C   1 
ATOM   18754 O O   . GLN D 1 613 ? 132.607 150.939 172.294 1.00 58.22  ? 613 GLN D O   1 
ATOM   18755 C CB  . GLN D 1 613 ? 133.376 148.797 170.476 1.00 54.32  ? 613 GLN D CB  1 
ATOM   18756 C CG  . GLN D 1 613 ? 134.366 148.076 171.394 1.00 55.43  ? 613 GLN D CG  1 
ATOM   18757 C CD  . GLN D 1 613 ? 135.470 147.363 170.619 1.00 59.42  ? 613 GLN D CD  1 
ATOM   18758 O OE1 . GLN D 1 613 ? 135.774 147.658 169.475 1.00 56.55  ? 613 GLN D OE1 1 
ATOM   18759 N NE2 . GLN D 1 613 ? 136.113 146.383 171.208 1.00 60.31  ? 613 GLN D NE2 1 
ATOM   18760 N N   . GLU D 1 614 ? 130.984 149.690 173.204 1.00 63.21  ? 614 GLU D N   1 
ATOM   18761 C CA  . GLU D 1 614 ? 130.475 150.706 174.139 1.00 61.27  ? 614 GLU D CA  1 
ATOM   18762 C C   . GLU D 1 614 ? 131.532 151.404 175.012 1.00 63.59  ? 614 GLU D C   1 
ATOM   18763 O O   . GLU D 1 614 ? 131.353 152.576 175.335 1.00 62.79  ? 614 GLU D O   1 
ATOM   18764 C CB  . GLU D 1 614 ? 129.380 150.117 175.037 1.00 60.87  ? 614 GLU D CB  1 
ATOM   18765 C CG  . GLU D 1 614 ? 128.094 149.765 174.275 1.00 60.22  ? 614 GLU D CG  1 
ATOM   18766 C CD  . GLU D 1 614 ? 126.835 149.825 175.162 1.00 64.79  ? 614 GLU D CD  1 
ATOM   18767 O OE1 . GLU D 1 614 ? 126.930 149.626 176.393 1.00 65.08  ? 614 GLU D OE1 1 
ATOM   18768 O OE2 . GLU D 1 614 ? 125.737 150.076 174.628 1.00 63.71  ? 614 GLU D OE2 1 
ATOM   18769 N N   . GLN D 1 615 ? 132.653 150.728 175.296 1.00 62.95  ? 615 GLN D N   1 
ATOM   18770 C CA  . GLN D 1 615 ? 133.691 151.275 176.225 1.00 59.32  ? 615 GLN D CA  1 
ATOM   18771 C C   . GLN D 1 615 ? 134.525 152.399 175.587 1.00 62.86  ? 615 GLN D C   1 
ATOM   18772 O O   . GLN D 1 615 ? 135.229 153.093 176.348 1.00 64.23  ? 615 GLN D O   1 
ATOM   18773 C CB  . GLN D 1 615 ? 134.587 150.129 176.711 1.00 61.20  ? 615 GLN D CB  1 
ATOM   18774 C CG  . GLN D 1 615 ? 135.483 149.515 175.620 1.00 61.61  ? 615 GLN D CG  1 
ATOM   18775 C CD  . GLN D 1 615 ? 136.392 148.438 176.160 1.00 64.79  ? 615 GLN D CD  1 
ATOM   18776 O OE1 . GLN D 1 615 ? 136.396 148.143 177.354 1.00 64.43  ? 615 GLN D OE1 1 
ATOM   18777 N NE2 . GLN D 1 615 ? 137.176 147.841 175.278 1.00 64.41  ? 615 GLN D NE2 1 
ATOM   18778 N N   . LEU D 1 616 ? 134.459 152.583 174.266 1.00 59.15  ? 616 LEU D N   1 
ATOM   18779 C CA  . LEU D 1 616 ? 135.239 153.598 173.554 1.00 53.20  ? 616 LEU D CA  1 
ATOM   18780 C C   . LEU D 1 616 ? 134.501 154.939 173.490 1.00 53.29  ? 616 LEU D C   1 
ATOM   18781 O O   . LEU D 1 616 ? 133.296 154.997 173.264 1.00 55.78  ? 616 LEU D O   1 
ATOM   18782 C CB  . LEU D 1 616 ? 135.593 153.103 172.140 1.00 55.45  ? 616 LEU D CB  1 
ATOM   18783 C CG  . LEU D 1 616 ? 136.441 151.831 172.064 1.00 55.14  ? 616 LEU D CG  1 
ATOM   18784 C CD1 . LEU D 1 616 ? 136.714 151.484 170.604 1.00 49.36  ? 616 LEU D CD1 1 
ATOM   18785 C CD2 . LEU D 1 616 ? 137.777 151.979 172.781 1.00 53.97  ? 616 LEU D CD2 1 
ATOM   18786 N N   . ARG D 1 617 ? 135.343 155.988 173.393 1.00 50.29  ? 617 ARG D N   1 
ATOM   18787 C CA  . ARG D 1 617 ? 134.858 157.343 173.041 1.00 48.29  ? 617 ARG D CA  1 
ATOM   18788 C C   . ARG D 1 617 ? 134.974 157.294 171.521 1.00 55.05  ? 617 ARG D C   1 
ATOM   18789 O O   . ARG D 1 617 ? 135.883 156.590 171.038 1.00 57.28  ? 617 ARG D O   1 
ATOM   18790 C CB  . ARG D 1 617 ? 135.798 158.394 173.629 1.00 50.25  ? 617 ARG D CB  1 
ATOM   18791 C CG  . ARG D 1 617 ? 135.326 159.847 173.533 1.00 48.10  ? 617 ARG D CG  1 
ATOM   18792 C CD  . ARG D 1 617 ? 136.408 160.713 174.183 1.00 53.85  ? 617 ARG D CD  1 
ATOM   18793 N NE  . ARG D 1 617 ? 136.075 162.128 174.244 1.00 55.88  ? 617 ARG D NE  1 
ATOM   18794 C CZ  . ARG D 1 617 ? 136.820 163.045 174.852 1.00 57.83  ? 617 ARG D CZ  1 
ATOM   18795 N NH1 . ARG D 1 617 ? 136.440 164.310 174.858 1.00 55.30  ? 617 ARG D NH1 1 
ATOM   18796 N NH2 . ARG D 1 617 ? 137.939 162.690 175.457 1.00 58.19  ? 617 ARG D NH2 1 
ATOM   18797 N N   . PHE D 1 618 ? 134.116 157.986 170.790 1.00 48.42  ? 618 PHE D N   1 
ATOM   18798 C CA  . PHE D 1 618 ? 134.060 157.895 169.321 1.00 46.14  ? 618 PHE D CA  1 
ATOM   18799 C C   . PHE D 1 618 ? 133.724 156.486 168.791 1.00 45.71  ? 618 PHE D C   1 
ATOM   18800 O O   . PHE D 1 618 ? 134.025 156.165 167.643 1.00 51.18  ? 618 PHE D O   1 
ATOM   18801 C CB  . PHE D 1 618 ? 135.319 158.493 168.665 1.00 40.68  ? 618 PHE D CB  1 
ATOM   18802 C CG  . PHE D 1 618 ? 135.828 159.780 169.270 1.00 39.63  ? 618 PHE D CG  1 
ATOM   18803 C CD1 . PHE D 1 618 ? 135.079 160.960 169.134 1.00 39.29  ? 618 PHE D CD1 1 
ATOM   18804 C CD2 . PHE D 1 618 ? 137.052 159.803 169.957 1.00 40.58  ? 618 PHE D CD2 1 
ATOM   18805 C CE1 . PHE D 1 618 ? 135.562 162.161 169.667 1.00 40.53  ? 618 PHE D CE1 1 
ATOM   18806 C CE2 . PHE D 1 618 ? 137.530 161.004 170.496 1.00 41.63  ? 618 PHE D CE2 1 
ATOM   18807 C CZ  . PHE D 1 618 ? 136.790 162.183 170.345 1.00 41.41  ? 618 PHE D CZ  1 
ATOM   18808 N N   . ARG D 1 619 ? 132.999 155.687 169.597 1.00 49.16  ? 619 ARG D N   1 
ATOM   18809 C CA  . ARG D 1 619 ? 132.613 154.282 169.231 1.00 46.22  ? 619 ARG D CA  1 
ATOM   18810 C C   . ARG D 1 619 ? 131.864 154.252 167.894 1.00 45.16  ? 619 ARG D C   1 
ATOM   18811 O O   . ARG D 1 619 ? 132.117 153.322 167.103 1.00 49.02  ? 619 ARG D O   1 
ATOM   18812 C CB  . ARG D 1 619 ? 131.870 153.645 170.420 1.00 49.60  ? 619 ARG D CB  1 
ATOM   18813 C CG  . ARG D 1 619 ? 130.617 154.408 170.872 1.00 47.42  ? 619 ARG D CG  1 
ATOM   18814 C CD  . ARG D 1 619 ? 130.044 153.763 172.132 1.00 53.03  ? 619 ARG D CD  1 
ATOM   18815 N NE  . ARG D 1 619 ? 128.750 154.340 172.467 1.00 55.32  ? 619 ARG D NE  1 
ATOM   18816 C CZ  . ARG D 1 619 ? 128.034 154.025 173.539 1.00 54.39  ? 619 ARG D CZ  1 
ATOM   18817 N NH1 . ARG D 1 619 ? 126.866 154.608 173.749 1.00 53.38  ? 619 ARG D NH1 1 
ATOM   18818 N NH2 . ARG D 1 619 ? 128.488 153.133 174.400 1.00 51.50  ? 619 ARG D NH2 1 
ATOM   18819 N N   . GLY D 1 620 ? 130.991 155.226 167.650 1.00 38.48  ? 620 GLY D N   1 
ATOM   18820 C CA  . GLY D 1 620 ? 130.246 155.329 166.395 1.00 36.24  ? 620 GLY D CA  1 
ATOM   18821 C C   . GLY D 1 620 ? 131.149 155.582 165.191 1.00 35.65  ? 620 GLY D C   1 
ATOM   18822 O O   . GLY D 1 620 ? 130.959 154.975 164.144 1.00 40.80  ? 620 GLY D O   1 
ATOM   18823 N N   . VAL D 1 621 ? 132.197 156.395 165.341 1.00 37.08  ? 621 VAL D N   1 
ATOM   18824 C CA  . VAL D 1 621 ? 133.206 156.615 164.297 1.00 35.81  ? 621 VAL D CA  1 
ATOM   18825 C C   . VAL D 1 621 ? 134.094 155.378 164.114 1.00 29.44  ? 621 VAL D C   1 
ATOM   18826 O O   . VAL D 1 621 ? 134.390 155.017 162.984 1.00 33.63  ? 621 VAL D O   1 
ATOM   18827 C CB  . VAL D 1 621 ? 134.042 157.877 164.572 1.00 35.39  ? 621 VAL D CB  1 
ATOM   18828 C CG1 . VAL D 1 621 ? 135.047 158.162 163.447 1.00 35.33  ? 621 VAL D CG1 1 
ATOM   18829 C CG2 . VAL D 1 621 ? 133.156 159.121 164.708 1.00 33.60  ? 621 VAL D CG2 1 
ATOM   18830 N N   . VAL D 1 622 ? 134.442 154.664 165.187 1.00 29.69  ? 622 VAL D N   1 
ATOM   18831 C CA  . VAL D 1 622 ? 135.137 153.366 165.117 1.00 24.91  ? 622 VAL D CA  1 
ATOM   18832 C C   . VAL D 1 622 ? 134.310 152.329 164.353 1.00 30.18  ? 622 VAL D C   1 
ATOM   18833 O O   . VAL D 1 622 ? 134.836 151.658 163.472 1.00 34.00  ? 622 VAL D O   1 
ATOM   18834 C CB  . VAL D 1 622 ? 135.520 152.882 166.528 1.00 25.76  ? 622 VAL D CB  1 
ATOM   18835 C CG1 . VAL D 1 622 ? 136.021 151.437 166.571 1.00 31.88  ? 622 VAL D CG1 1 
ATOM   18836 C CG2 . VAL D 1 622 ? 136.629 153.767 167.101 1.00 27.91  ? 622 VAL D CG2 1 
ATOM   18837 N N   . LEU D 1 623 ? 133.001 152.234 164.604 1.00 31.67  ? 623 LEU D N   1 
ATOM   18838 C CA  . LEU D 1 623 ? 132.113 151.368 163.838 1.00 24.31  ? 623 LEU D CA  1 
ATOM   18839 C C   . LEU D 1 623 ? 131.997 151.796 162.366 1.00 25.46  ? 623 LEU D C   1 
ATOM   18840 O O   . LEU D 1 623 ? 132.024 150.945 161.487 1.00 36.29  ? 623 LEU D O   1 
ATOM   18841 C CB  . LEU D 1 623 ? 130.741 151.293 164.532 1.00 32.22  ? 623 LEU D CB  1 
ATOM   18842 C CG  . LEU D 1 623 ? 129.734 150.377 163.811 1.00 33.08  ? 623 LEU D CG  1 
ATOM   18843 C CD1 . LEU D 1 623 ? 130.210 148.928 163.763 1.00 30.82  ? 623 LEU D CD1 1 
ATOM   18844 C CD2 . LEU D 1 623 ? 128.385 150.407 164.515 1.00 31.54  ? 623 LEU D CD2 1 
ATOM   18845 N N   . LEU D 1 624 ? 131.907 153.092 162.068 1.00 26.84  ? 624 LEU D N   1 
ATOM   18846 C CA  . LEU D 1 624 ? 131.894 153.581 160.691 1.00 23.45  ? 624 LEU D CA  1 
ATOM   18847 C C   . LEU D 1 624 ? 133.215 153.336 159.953 1.00 27.42  ? 624 LEU D C   1 
ATOM   18848 O O   . LEU D 1 624 ? 133.176 153.001 158.775 1.00 30.91  ? 624 LEU D O   1 
ATOM   18849 C CB  . LEU D 1 624 ? 131.518 155.071 160.663 1.00 33.65  ? 624 LEU D CB  1 
ATOM   18850 C CG  . LEU D 1 624 ? 130.048 155.353 161.006 1.00 36.55  ? 624 LEU D CG  1 
ATOM   18851 C CD1 . LEU D 1 624 ? 129.861 156.857 161.185 1.00 32.51  ? 624 LEU D CD1 1 
ATOM   18852 C CD2 . LEU D 1 624 ? 129.090 154.877 159.914 1.00 27.71  ? 624 LEU D CD2 1 
ATOM   18853 N N   . LEU D 1 625 ? 134.374 153.438 160.613 1.00 30.25  ? 625 LEU D N   1 
ATOM   18854 C CA  . LEU D 1 625 ? 135.661 153.020 160.052 1.00 19.89  ? 625 LEU D CA  1 
ATOM   18855 C C   . LEU D 1 625 ? 135.680 151.527 159.721 1.00 19.98  ? 625 LEU D C   1 
ATOM   18856 O O   . LEU D 1 625 ? 136.116 151.157 158.637 1.00 32.40  ? 625 LEU D O   1 
ATOM   18857 C CB  . LEU D 1 625 ? 136.814 153.338 161.023 1.00 30.12  ? 625 LEU D CB  1 
ATOM   18858 C CG  . LEU D 1 625 ? 137.228 154.811 161.101 1.00 28.72  ? 625 LEU D CG  1 
ATOM   18859 C CD1 . LEU D 1 625 ? 138.257 154.988 162.219 1.00 28.41  ? 625 LEU D CD1 1 
ATOM   18860 C CD2 . LEU D 1 625 ? 137.863 155.297 159.801 1.00 26.71  ? 625 LEU D CD2 1 
ATOM   18861 N N   . LEU D 1 626 ? 135.192 150.662 160.615 1.00 20.32  ? 626 LEU D N   1 
ATOM   18862 C CA  . LEU D 1 626 ? 135.088 149.229 160.350 1.00 19.10  ? 626 LEU D CA  1 
ATOM   18863 C C   . LEU D 1 626 ? 134.131 148.925 159.199 1.00 18.91  ? 626 LEU D C   1 
ATOM   18864 O O   . LEU D 1 626 ? 134.493 148.184 158.297 1.00 30.86  ? 626 LEU D O   1 
ATOM   18865 C CB  . LEU D 1 626 ? 134.650 148.482 161.615 1.00 28.01  ? 626 LEU D CB  1 
ATOM   18866 C CG  . LEU D 1 626 ? 135.729 148.402 162.696 1.00 22.99  ? 626 LEU D CG  1 
ATOM   18867 C CD1 . LEU D 1 626 ? 135.103 147.906 163.994 1.00 25.86  ? 626 LEU D CD1 1 
ATOM   18868 C CD2 . LEU D 1 626 ? 136.842 147.446 162.287 1.00 18.17  ? 626 LEU D CD2 1 
ATOM   18869 N N   . LEU D 1 627 ? 132.939 149.520 159.173 1.00 21.80  ? 627 LEU D N   1 
ATOM   18870 C CA  . LEU D 1 627 ? 132.001 149.347 158.070 1.00 17.73  ? 627 LEU D CA  1 
ATOM   18871 C C   . LEU D 1 627 ? 132.578 149.859 156.744 1.00 12.70  ? 627 LEU D C   1 
ATOM   18872 O O   . LEU D 1 627 ? 132.456 149.178 155.737 1.00 30.79  ? 627 LEU D O   1 
ATOM   18873 C CB  . LEU D 1 627 ? 130.655 150.013 158.401 1.00 22.68  ? 627 LEU D CB  1 
ATOM   18874 C CG  . LEU D 1 627 ? 129.857 149.316 159.519 1.00 25.55  ? 627 LEU D CG  1 
ATOM   18875 C CD1 . LEU D 1 627 ? 128.654 150.174 159.889 1.00 22.00  ? 627 LEU D CD1 1 
ATOM   18876 C CD2 . LEU D 1 627 ? 129.362 147.935 159.114 1.00 20.39  ? 627 LEU D CD2 1 
ATOM   18877 N N   . ALA D 1 628 ? 133.258 151.008 156.726 1.00 23.87  ? 628 ALA D N   1 
ATOM   18878 C CA  . ALA D 1 628 ? 133.968 151.493 155.548 1.00 9.93   ? 628 ALA D CA  1 
ATOM   18879 C C   . ALA D 1 628 ? 135.084 150.542 155.095 1.00 16.87  ? 628 ALA D C   1 
ATOM   18880 O O   . ALA D 1 628 ? 135.142 150.212 153.918 1.00 26.01  ? 628 ALA D O   1 
ATOM   18881 C CB  . ALA D 1 628 ? 134.507 152.893 155.822 1.00 19.84  ? 628 ALA D CB  1 
ATOM   18882 N N   . TYR D 1 629 ? 135.935 150.042 155.996 1.00 16.75  ? 629 TYR D N   1 
ATOM   18883 C CA  . TYR D 1 629 ? 136.948 149.054 155.653 1.00 6.28   ? 629 TYR D CA  1 
ATOM   18884 C C   . TYR D 1 629 ? 136.337 147.778 155.062 1.00 15.99  ? 629 TYR D C   1 
ATOM   18885 O O   . TYR D 1 629 ? 136.824 147.286 154.048 1.00 23.77  ? 629 TYR D O   1 
ATOM   18886 C CB  . TYR D 1 629 ? 137.807 148.725 156.880 1.00 5.28   ? 629 TYR D CB  1 
ATOM   18887 C CG  . TYR D 1 629 ? 138.701 147.521 156.682 1.00 15.81  ? 629 TYR D CG  1 
ATOM   18888 C CD1 . TYR D 1 629 ? 139.962 147.647 156.067 1.00 9.76   ? 629 TYR D CD1 1 
ATOM   18889 C CD2 . TYR D 1 629 ? 138.218 146.249 157.042 1.00 17.01  ? 629 TYR D CD2 1 
ATOM   18890 C CE1 . TYR D 1 629 ? 140.745 146.504 155.833 1.00 5.27   ? 629 TYR D CE1 1 
ATOM   18891 C CE2 . TYR D 1 629 ? 138.994 145.113 156.803 1.00 7.54   ? 629 TYR D CE2 1 
ATOM   18892 C CZ  . TYR D 1 629 ? 140.257 145.232 156.194 1.00 15.97  ? 629 TYR D CZ  1 
ATOM   18893 O OH  . TYR D 1 629 ? 141.006 144.118 156.022 1.00 29.31  ? 629 TYR D OH  1 
ATOM   18894 N N   . VAL D 1 630 ? 135.264 147.241 155.648 1.00 17.51  ? 630 VAL D N   1 
ATOM   18895 C CA  . VAL D 1 630 ? 134.580 146.043 155.146 1.00 18.70  ? 630 VAL D CA  1 
ATOM   18896 C C   . VAL D 1 630 ? 134.041 146.267 153.740 1.00 18.25  ? 630 VAL D C   1 
ATOM   18897 O O   . VAL D 1 630 ? 134.338 145.487 152.839 1.00 28.99  ? 630 VAL D O   1 
ATOM   18898 C CB  . VAL D 1 630 ? 133.460 145.615 156.109 1.00 26.54  ? 630 VAL D CB  1 
ATOM   18899 C CG1 . VAL D 1 630 ? 132.519 144.569 155.510 1.00 26.33  ? 630 VAL D CG1 1 
ATOM   18900 C CG2 . VAL D 1 630 ? 134.061 145.011 157.375 1.00 11.69  ? 630 VAL D CG2 1 
ATOM   18901 N N   . LEU D 1 631 ? 133.298 147.349 153.516 1.00 19.24  ? 631 LEU D N   1 
ATOM   18902 C CA  . LEU D 1 631 ? 132.728 147.661 152.211 1.00 12.55  ? 631 LEU D CA  1 
ATOM   18903 C C   . LEU D 1 631 ? 133.810 147.928 151.152 1.00 23.87  ? 631 LEU D C   1 
ATOM   18904 O O   . LEU D 1 631 ? 133.725 147.389 150.057 1.00 33.83  ? 631 LEU D O   1 
ATOM   18905 C CB  . LEU D 1 631 ? 131.747 148.832 152.353 1.00 23.19  ? 631 LEU D CB  1 
ATOM   18906 C CG  . LEU D 1 631 ? 130.507 148.517 153.215 1.00 27.07  ? 631 LEU D CG  1 
ATOM   18907 C CD1 . LEU D 1 631 ? 129.727 149.799 153.478 1.00 25.75  ? 631 LEU D CD1 1 
ATOM   18908 C CD2 . LEU D 1 631 ? 129.574 147.507 152.553 1.00 22.48  ? 631 LEU D CD2 1 
ATOM   18909 N N   . LEU D 1 632 ? 134.871 148.674 151.467 1.00 18.97  ? 632 LEU D N   1 
ATOM   18910 C CA  . LEU D 1 632 ? 136.009 148.872 150.562 1.00 11.83  ? 632 LEU D CA  1 
ATOM   18911 C C   . LEU D 1 632 ? 136.745 147.572 150.244 1.00 8.93   ? 632 LEU D C   1 
ATOM   18912 O O   . LEU D 1 632 ? 137.082 147.310 149.098 1.00 29.87  ? 632 LEU D O   1 
ATOM   18913 C CB  . LEU D 1 632 ? 136.994 149.872 151.183 1.00 23.81  ? 632 LEU D CB  1 
ATOM   18914 C CG  . LEU D 1 632 ? 136.481 151.315 151.240 1.00 22.99  ? 632 LEU D CG  1 
ATOM   18915 C CD1 . LEU D 1 632 ? 137.421 152.172 152.068 1.00 20.41  ? 632 LEU D CD1 1 
ATOM   18916 C CD2 . LEU D 1 632 ? 136.397 151.930 149.856 1.00 18.01  ? 632 LEU D CD2 1 
ATOM   18917 N N   . THR D 1 633 ? 136.973 146.726 151.244 1.00 27.45  ? 633 THR D N   1 
ATOM   18918 C CA  . THR D 1 633 ? 137.660 145.441 151.080 1.00 18.98  ? 633 THR D CA  1 
ATOM   18919 C C   . THR D 1 633 ? 136.834 144.466 150.251 1.00 14.74  ? 633 THR D C   1 
ATOM   18920 O O   . THR D 1 633 ? 137.384 143.761 149.416 1.00 28.45  ? 633 THR D O   1 
ATOM   18921 C CB  . THR D 1 633 ? 137.992 144.854 152.454 1.00 17.84  ? 633 THR D CB  1 
ATOM   18922 O OG1 . THR D 1 633 ? 138.842 145.749 153.106 1.00 23.68  ? 633 THR D OG1 1 
ATOM   18923 C CG2 . THR D 1 633 ? 138.707 143.512 152.418 1.00 24.95  ? 633 THR D CG2 1 
ATOM   18924 N N   . TYR D 1 634 ? 135.515 144.446 150.412 1.00 20.58  ? 634 TYR D N   1 
ATOM   18925 C CA  . TYR D 1 634 ? 134.631 143.590 149.627 1.00 15.36  ? 634 TYR D CA  1 
ATOM   18926 C C   . TYR D 1 634 ? 134.499 144.086 148.180 1.00 20.26  ? 634 TYR D C   1 
ATOM   18927 O O   . TYR D 1 634 ? 134.496 143.261 147.270 1.00 29.47  ? 634 TYR D O   1 
ATOM   18928 C CB  . TYR D 1 634 ? 133.270 143.409 150.303 1.00 22.68  ? 634 TYR D CB  1 
ATOM   18929 C CG  . TYR D 1 634 ? 133.307 142.395 151.419 1.00 33.91  ? 634 TYR D CG  1 
ATOM   18930 C CD1 . TYR D 1 634 ? 134.463 142.210 152.163 1.00 36.83  ? 634 TYR D CD1 1 
ATOM   18931 C CD2 . TYR D 1 634 ? 132.210 141.611 151.731 1.00 30.24  ? 634 TYR D CD2 1 
ATOM   18932 C CE1 . TYR D 1 634 ? 134.532 141.284 153.187 1.00 25.80  ? 634 TYR D CE1 1 
ATOM   18933 C CE2 . TYR D 1 634 ? 132.260 140.675 152.752 1.00 26.82  ? 634 TYR D CE2 1 
ATOM   18934 C CZ  . TYR D 1 634 ? 133.426 140.512 153.481 1.00 30.48  ? 634 TYR D CZ  1 
ATOM   18935 O OH  . TYR D 1 634 ? 133.499 139.600 154.491 1.00 37.21  ? 634 TYR D OH  1 
ATOM   18936 N N   . VAL D 1 635 ? 134.484 145.403 147.951 1.00 24.04  ? 635 VAL D N   1 
ATOM   18937 C CA  . VAL D 1 635 ? 134.619 146.004 146.621 1.00 18.90  ? 635 VAL D CA  1 
ATOM   18938 C C   . VAL D 1 635 ? 135.959 145.621 145.990 1.00 17.54  ? 635 VAL D C   1 
ATOM   18939 O O   . VAL D 1 635 ? 135.977 145.185 144.847 1.00 27.82  ? 635 VAL D O   1 
ATOM   18940 C CB  . VAL D 1 635 ? 134.455 147.534 146.682 1.00 24.50  ? 635 VAL D CB  1 
ATOM   18941 C CG1 . VAL D 1 635 ? 134.782 148.235 145.359 1.00 24.17  ? 635 VAL D CG1 1 
ATOM   18942 C CG2 . VAL D 1 635 ? 133.030 147.947 147.025 1.00 24.95  ? 635 VAL D CG2 1 
ATOM   18943 N N   . LEU D 1 636 ? 137.081 145.728 146.706 1.00 15.80  ? 636 LEU D N   1 
ATOM   18944 C CA  . LEU D 1 636 ? 138.400 145.333 146.212 1.00 12.37  ? 636 LEU D CA  1 
ATOM   18945 C C   . LEU D 1 636 ? 138.504 143.833 145.903 1.00 18.40  ? 636 LEU D C   1 
ATOM   18946 O O   . LEU D 1 636 ? 138.995 143.477 144.841 1.00 31.14  ? 636 LEU D O   1 
ATOM   18947 C CB  . LEU D 1 636 ? 139.457 145.781 147.236 1.00 23.96  ? 636 LEU D CB  1 
ATOM   18948 C CG  . LEU D 1 636 ? 140.893 145.313 146.930 1.00 28.74  ? 636 LEU D CG  1 
ATOM   18949 C CD1 . LEU D 1 636 ? 141.470 146.000 145.702 1.00 26.57  ? 636 LEU D CD1 1 
ATOM   18950 C CD2 . LEU D 1 636 ? 141.800 145.604 148.117 1.00 30.03  ? 636 LEU D CD2 1 
ATOM   18951 N N   . LEU D 1 637 ? 138.040 142.951 146.790 1.00 18.86  ? 637 LEU D N   1 
ATOM   18952 C CA  . LEU D 1 637 ? 138.072 141.504 146.580 1.00 14.46  ? 637 LEU D CA  1 
ATOM   18953 C C   . LEU D 1 637 ? 137.183 141.087 145.409 1.00 20.10  ? 637 LEU D C   1 
ATOM   18954 O O   . LEU D 1 637 ? 137.597 140.299 144.572 1.00 23.17  ? 637 LEU D O   1 
ATOM   18955 C CB  . LEU D 1 637 ? 137.656 140.777 147.869 1.00 24.62  ? 637 LEU D CB  1 
ATOM   18956 C CG  . LEU D 1 637 ? 138.717 140.819 148.987 1.00 28.24  ? 637 LEU D CG  1 
ATOM   18957 C CD1 . LEU D 1 637 ? 138.105 140.337 150.302 1.00 25.87  ? 637 LEU D CD1 1 
ATOM   18958 C CD2 . LEU D 1 637 ? 139.914 139.931 148.671 1.00 23.64  ? 637 LEU D CD2 1 
ATOM   18959 N N   . LEU D 1 638 ? 135.990 141.655 145.295 1.00 22.53  ? 638 LEU D N   1 
ATOM   18960 C CA  . LEU D 1 638 ? 135.081 141.399 144.189 1.00 18.92  ? 638 LEU D CA  1 
ATOM   18961 C C   . LEU D 1 638 ? 135.641 141.885 142.848 1.00 15.03  ? 638 LEU D C   1 
ATOM   18962 O O   . LEU D 1 638 ? 135.614 141.155 141.869 1.00 29.96  ? 638 LEU D O   1 
ATOM   18963 C CB  . LEU D 1 638 ? 133.744 142.049 144.560 1.00 25.88  ? 638 LEU D CB  1 
ATOM   18964 C CG  . LEU D 1 638 ? 132.624 141.921 143.531 1.00 21.05  ? 638 LEU D CG  1 
ATOM   18965 C CD1 . LEU D 1 638 ? 132.377 140.483 143.112 1.00 22.24  ? 638 LEU D CD1 1 
ATOM   18966 C CD2 . LEU D 1 638 ? 131.351 142.474 144.154 1.00 17.90  ? 638 LEU D CD2 1 
ATOM   18967 N N   . ASN D 1 639 ? 136.227 143.079 142.810 1.00 24.10  ? 639 ASN D N   1 
ATOM   18968 C CA  . ASN D 1 639 ? 136.964 143.581 141.654 1.00 18.52  ? 639 ASN D CA  1 
ATOM   18969 C C   . ASN D 1 639 ? 138.158 142.684 141.281 1.00 18.20  ? 639 ASN D C   1 
ATOM   18970 O O   . ASN D 1 639 ? 138.324 142.348 140.118 1.00 23.90  ? 639 ASN D O   1 
ATOM   18971 C CB  . ASN D 1 639 ? 137.434 145.005 141.953 1.00 19.15  ? 639 ASN D CB  1 
ATOM   18972 C CG  . ASN D 1 639 ? 136.439 146.071 141.545 1.00 24.18  ? 639 ASN D CG  1 
ATOM   18973 O OD1 . ASN D 1 639 ? 136.201 146.333 140.384 1.00 31.22  ? 639 ASN D OD1 1 
ATOM   18974 N ND2 . ASN D 1 639 ? 135.811 146.731 142.477 1.00 30.95  ? 639 ASN D ND2 1 
ATOM   18975 N N   . MET D 1 640 ? 138.963 142.252 142.247 1.00 25.09  ? 640 MET D N   1 
ATOM   18976 C CA  . MET D 1 640 ? 140.083 141.338 142.041 1.00 18.01  ? 640 MET D CA  1 
ATOM   18977 C C   . MET D 1 640 ? 139.645 139.985 141.471 1.00 21.18  ? 640 MET D C   1 
ATOM   18978 O O   . MET D 1 640 ? 140.236 139.511 140.508 1.00 31.21  ? 640 MET D O   1 
ATOM   18979 C CB  . MET D 1 640 ? 140.836 141.202 143.372 1.00 24.23  ? 640 MET D CB  1 
ATOM   18980 C CG  . MET D 1 640 ? 142.071 140.300 143.328 1.00 26.88  ? 640 MET D CG  1 
ATOM   18981 S SD  . MET D 1 640 ? 141.844 138.543 143.657 1.00 40.73  ? 640 MET D SD  1 
ATOM   18982 C CE  . MET D 1 640 ? 141.377 138.558 145.399 1.00 27.25  ? 640 MET D CE  1 
ATOM   18983 N N   . LEU D 1 641 ? 138.580 139.382 142.001 1.00 24.58  ? 641 LEU D N   1 
ATOM   18984 C CA  . LEU D 1 641 ? 138.050 138.108 141.510 1.00 21.40  ? 641 LEU D CA  1 
ATOM   18985 C C   . LEU D 1 641 ? 137.490 138.219 140.091 1.00 19.67  ? 641 LEU D C   1 
ATOM   18986 O O   . LEU D 1 641 ? 137.792 137.385 139.247 1.00 26.59  ? 641 LEU D O   1 
ATOM   18987 C CB  . LEU D 1 641 ? 136.983 137.582 142.484 1.00 26.34  ? 641 LEU D CB  1 
ATOM   18988 C CG  . LEU D 1 641 ? 137.544 137.135 143.844 1.00 30.82  ? 641 LEU D CG  1 
ATOM   18989 C CD1 . LEU D 1 641 ? 136.406 136.869 144.820 1.00 27.86  ? 641 LEU D CD1 1 
ATOM   18990 C CD2 . LEU D 1 641 ? 138.390 135.878 143.730 1.00 24.89  ? 641 LEU D CD2 1 
ATOM   18991 N N   . ILE D 1 642 ? 136.706 139.253 139.805 1.00 24.89  ? 642 ILE D N   1 
ATOM   18992 C CA  . ILE D 1 642 ? 136.175 139.501 138.465 1.00 19.62  ? 642 ILE D CA  1 
ATOM   18993 C C   . ILE D 1 642 ? 137.306 139.800 137.467 1.00 19.82  ? 642 ILE D C   1 
ATOM   18994 O O   . ILE D 1 642 ? 137.310 139.240 136.374 1.00 32.42  ? 642 ILE D O   1 
ATOM   18995 C CB  . ILE D 1 642 ? 135.114 140.618 138.543 1.00 27.53  ? 642 ILE D CB  1 
ATOM   18996 C CG1 . ILE D 1 642 ? 133.811 140.164 139.241 1.00 21.68  ? 642 ILE D CG1 1 
ATOM   18997 C CG2 . ILE D 1 642 ? 134.793 141.179 137.162 1.00 26.55  ? 642 ILE D CG2 1 
ATOM   18998 C CD1 . ILE D 1 642 ? 132.972 139.117 138.506 1.00 23.53  ? 642 ILE D CD1 1 
ATOM   18999 N N   . ALA D 1 643 ? 138.313 140.593 137.834 1.00 23.64  ? 643 ALA D N   1 
ATOM   19000 C CA  . ALA D 1 643 ? 139.484 140.826 136.997 1.00 12.63  ? 643 ALA D CA  1 
ATOM   19001 C C   . ALA D 1 643 ? 140.313 139.553 136.741 1.00 18.95  ? 643 ALA D C   1 
ATOM   19002 O O   . ALA D 1 643 ? 140.818 139.383 135.637 1.00 35.66  ? 643 ALA D O   1 
ATOM   19003 C CB  . ALA D 1 643 ? 140.330 141.936 137.626 1.00 21.55  ? 643 ALA D CB  1 
ATOM   19004 N N   . LEU D 1 644 ? 140.425 138.621 137.696 1.00 30.99  ? 644 LEU D N   1 
ATOM   19005 C CA  . LEU D 1 644 ? 141.014 137.302 137.438 1.00 24.98  ? 644 LEU D CA  1 
ATOM   19006 C C   . LEU D 1 644 ? 140.186 136.476 136.461 1.00 24.51  ? 644 LEU D C   1 
ATOM   19007 O O   . LEU D 1 644 ? 140.763 135.876 135.563 1.00 34.03  ? 644 LEU D O   1 
ATOM   19008 C CB  . LEU D 1 644 ? 141.192 136.504 138.735 1.00 26.64  ? 644 LEU D CB  1 
ATOM   19009 C CG  . LEU D 1 644 ? 142.351 136.960 139.622 1.00 31.14  ? 644 LEU D CG  1 
ATOM   19010 C CD1 . LEU D 1 644 ? 142.326 136.126 140.894 1.00 27.84  ? 644 LEU D CD1 1 
ATOM   19011 C CD2 . LEU D 1 644 ? 143.710 136.760 138.955 1.00 34.04  ? 644 LEU D CD2 1 
ATOM   19012 N N   . MET D 1 645 ? 138.858 136.435 136.578 1.00 32.70  ? 645 MET D N   1 
ATOM   19013 C CA  . MET D 1 645 ? 138.007 135.718 135.623 1.00 28.86  ? 645 MET D CA  1 
ATOM   19014 C C   . MET D 1 645 ? 138.152 136.262 134.198 1.00 31.61  ? 645 MET D C   1 
ATOM   19015 O O   . MET D 1 645 ? 138.384 135.480 133.283 1.00 37.35  ? 645 MET D O   1 
ATOM   19016 C CB  . MET D 1 645 ? 136.544 135.758 136.055 1.00 29.17  ? 645 MET D CB  1 
ATOM   19017 C CG  . MET D 1 645 ? 136.303 134.950 137.322 1.00 32.65  ? 645 MET D CG  1 
ATOM   19018 S SD  . MET D 1 645 ? 134.641 135.150 137.997 1.00 52.21  ? 645 MET D SD  1 
ATOM   19019 C CE  . MET D 1 645 ? 134.984 134.646 139.700 1.00 37.43  ? 645 MET D CE  1 
ATOM   19020 N N   . SER D 1 646 ? 138.113 137.585 134.002 1.00 33.02  ? 646 SER D N   1 
ATOM   19021 C CA  . SER D 1 646 ? 138.319 138.225 132.697 1.00 32.03  ? 646 SER D CA  1 
ATOM   19022 C C   . SER D 1 646 ? 139.671 137.883 132.059 1.00 37.47  ? 646 SER D C   1 
ATOM   19023 O O   . SER D 1 646 ? 139.782 137.839 130.840 1.00 45.37  ? 646 SER D O   1 
ATOM   19024 C CB  . SER D 1 646 ? 138.235 139.750 132.816 1.00 27.85  ? 646 SER D CB  1 
ATOM   19025 O OG  . SER D 1 646 ? 137.010 140.172 133.374 1.00 36.36  ? 646 SER D OG  1 
ATOM   19026 N N   . GLU D 1 647 ? 140.715 137.644 132.846 1.00 36.15  ? 647 GLU D N   1 
ATOM   19027 C CA  . GLU D 1 647 ? 142.041 137.293 132.332 1.00 36.22  ? 647 GLU D CA  1 
ATOM   19028 C C   . GLU D 1 647 ? 142.226 135.783 132.088 1.00 39.21  ? 647 GLU D C   1 
ATOM   19029 O O   . GLU D 1 647 ? 142.940 135.380 131.174 1.00 44.20  ? 647 GLU D O   1 
ATOM   19030 C CB  . GLU D 1 647 ? 143.088 137.836 133.313 1.00 35.63  ? 647 GLU D CB  1 
ATOM   19031 C CG  . GLU D 1 647 ? 144.551 137.605 132.907 1.00 45.33  ? 647 GLU D CG  1 
ATOM   19032 C CD  . GLU D 1 647 ? 145.056 138.515 131.772 1.00 50.47  ? 647 GLU D CD  1 
ATOM   19033 O OE1 . GLU D 1 647 ? 144.313 138.787 130.803 1.00 50.08  ? 647 GLU D OE1 1 
ATOM   19034 O OE2 . GLU D 1 647 ? 146.219 138.964 131.858 1.00 47.95  ? 647 GLU D OE2 1 
ATOM   19035 N N   . THR D 1 648 ? 141.595 134.932 132.898 1.00 35.61  ? 648 THR D N   1 
ATOM   19036 C CA  . THR D 1 648 ? 141.903 133.494 132.959 1.00 34.31  ? 648 THR D CA  1 
ATOM   19037 C C   . THR D 1 648 ? 140.869 132.575 132.305 1.00 35.08  ? 648 THR D C   1 
ATOM   19038 O O   . THR D 1 648 ? 141.225 131.458 131.935 1.00 40.24  ? 648 THR D O   1 
ATOM   19039 C CB  . THR D 1 648 ? 142.135 133.044 134.411 1.00 36.55  ? 648 THR D CB  1 
ATOM   19040 O OG1 . THR D 1 648 ? 141.008 133.292 135.203 1.00 40.46  ? 648 THR D OG1 1 
ATOM   19041 C CG2 . THR D 1 648 ? 143.341 133.696 135.084 1.00 28.28  ? 648 THR D CG2 1 
ATOM   19042 N N   . VAL D 1 649 ? 139.615 133.001 132.131 1.00 36.00  ? 649 VAL D N   1 
ATOM   19043 C CA  . VAL D 1 649 ? 138.495 132.160 131.657 1.00 38.52  ? 649 VAL D CA  1 
ATOM   19044 C C   . VAL D 1 649 ? 138.086 132.571 130.232 1.00 38.34  ? 649 VAL D C   1 
ATOM   19045 O O   . VAL D 1 649 ? 136.988 133.052 129.988 1.00 40.52  ? 649 VAL D O   1 
ATOM   19046 C CB  . VAL D 1 649 ? 137.325 132.143 132.674 1.00 39.25  ? 649 VAL D CB  1 
ATOM   19047 C CG1 . VAL D 1 649 ? 136.258 131.092 132.331 1.00 39.42  ? 649 VAL D CG1 1 
ATOM   19048 C CG2 . VAL D 1 649 ? 137.797 131.805 134.096 1.00 31.13  ? 649 VAL D CG2 1 
ATOM   19049 N N   . ASN D 1 650 ? 139.015 132.426 129.284 1.00 42.21  ? 650 ASN D N   1 
ATOM   19050 C CA  . ASN D 1 650 ? 138.928 132.943 127.910 1.00 39.29  ? 650 ASN D CA  1 
ATOM   19051 C C   . ASN D 1 650 ? 138.851 131.874 126.800 1.00 41.39  ? 650 ASN D C   1 
ATOM   19052 O O   . ASN D 1 650 ? 139.042 132.190 125.631 1.00 43.19  ? 650 ASN D O   1 
ATOM   19053 C CB  . ASN D 1 650 ? 140.070 133.956 127.693 1.00 44.19  ? 650 ASN D CB  1 
ATOM   19054 C CG  . ASN D 1 650 ? 139.803 135.278 128.393 1.00 48.36  ? 650 ASN D CG  1 
ATOM   19055 O OD1 . ASN D 1 650 ? 138.743 135.867 128.259 1.00 47.24  ? 650 ASN D OD1 1 
ATOM   19056 N ND2 . ASN D 1 650 ? 140.736 135.801 129.139 1.00 44.72  ? 650 ASN D ND2 1 
ATOM   19057 N N   . HIS D 1 651 ? 138.573 130.615 127.140 1.00 43.37  ? 651 HIS D N   1 
ATOM   19058 C CA  . HIS D 1 651 ? 138.392 129.484 126.202 1.00 39.98  ? 651 HIS D CA  1 
ATOM   19059 C C   . HIS D 1 651 ? 139.591 129.160 125.300 1.00 42.66  ? 651 HIS D C   1 
ATOM   19060 O O   . HIS D 1 651 ? 139.449 128.474 124.287 1.00 50.25  ? 651 HIS D O   1 
ATOM   19061 C CB  . HIS D 1 651 ? 137.138 129.736 125.347 1.00 42.40  ? 651 HIS D CB  1 
ATOM   19062 C CG  . HIS D 1 651 ? 135.945 130.135 126.150 1.00 41.23  ? 651 HIS D CG  1 
ATOM   19063 N ND1 . HIS D 1 651 ? 135.032 129.213 126.625 1.00 44.34  ? 651 HIS D ND1 1 
ATOM   19064 C CD2 . HIS D 1 651 ? 135.517 131.345 126.570 1.00 44.88  ? 651 HIS D CD2 1 
ATOM   19065 C CE1 . HIS D 1 651 ? 134.090 129.839 127.300 1.00 43.64  ? 651 HIS D CE1 1 
ATOM   19066 N NE2 . HIS D 1 651 ? 134.364 131.149 127.281 1.00 42.42  ? 651 HIS D NE2 1 
ATOM   19067 N N   . VAL D 1 652 ? 140.787 129.621 125.664 1.00 47.14  ? 652 VAL D N   1 
ATOM   19068 C CA  . VAL D 1 652 ? 142.040 129.201 125.028 1.00 44.64  ? 652 VAL D CA  1 
ATOM   19069 C C   . VAL D 1 652 ? 142.264 127.702 125.236 1.00 46.23  ? 652 VAL D C   1 
ATOM   19070 O O   . VAL D 1 652 ? 141.838 127.137 126.246 1.00 45.90  ? 652 VAL D O   1 
ATOM   19071 C CB  . VAL D 1 652 ? 143.239 130.026 125.522 1.00 45.38  ? 652 VAL D CB  1 
ATOM   19072 C CG1 . VAL D 1 652 ? 143.055 131.510 125.172 1.00 43.86  ? 652 VAL D CG1 1 
ATOM   19073 C CG2 . VAL D 1 652 ? 143.495 129.903 127.028 1.00 47.71  ? 652 VAL D CG2 1 
ATOM   19074 N N   . ALA D 1 653 ? 142.914 127.042 124.283 1.00 51.36  ? 653 ALA D N   1 
ATOM   19075 C CA  . ALA D 1 653 ? 143.171 125.606 124.357 1.00 51.38  ? 653 ALA D CA  1 
ATOM   19076 C C   . ALA D 1 653 ? 143.999 125.233 125.603 1.00 53.52  ? 653 ALA D C   1 
ATOM   19077 O O   . ALA D 1 653 ? 144.937 125.935 125.986 1.00 52.14  ? 653 ALA D O   1 
ATOM   19078 C CB  . ALA D 1 653 ? 143.844 125.159 123.059 1.00 49.84  ? 653 ALA D CB  1 
ATOM   19079 N N   . ASP D 1 654 ? 143.652 124.115 126.236 1.00 52.55  ? 654 ASP D N   1 
ATOM   19080 C CA  . ASP D 1 654 ? 144.305 123.621 127.449 1.00 50.58  ? 654 ASP D CA  1 
ATOM   19081 C C   . ASP D 1 654 ? 145.693 123.021 127.154 1.00 51.43  ? 654 ASP D C   1 
ATOM   19082 O O   . ASP D 1 654 ? 145.848 121.826 126.912 1.00 51.33  ? 654 ASP D O   1 
ATOM   19083 C CB  . ASP D 1 654 ? 143.363 122.611 128.123 1.00 52.20  ? 654 ASP D CB  1 
ATOM   19084 C CG  . ASP D 1 654 ? 143.950 122.030 129.408 1.00 57.76  ? 654 ASP D CG  1 
ATOM   19085 O OD1 . ASP D 1 654 ? 144.880 122.639 129.989 1.00 58.12  ? 654 ASP D OD1 1 
ATOM   19086 O OD2 . ASP D 1 654 ? 143.502 120.947 129.831 1.00 57.40  ? 654 ASP D OD2 1 
ATOM   19087 N N   . ASN D 1 655 ? 146.726 123.859 127.180 1.00 45.82  ? 655 ASN D N   1 
ATOM   19088 C CA  . ASN D 1 655 ? 148.127 123.496 126.943 1.00 42.19  ? 655 ASN D CA  1 
ATOM   19089 C C   . ASN D 1 655 ? 148.819 122.813 128.143 1.00 40.98  ? 655 ASN D C   1 
ATOM   19090 O O   . ASN D 1 655 ? 150.041 122.660 128.159 1.00 44.53  ? 655 ASN D O   1 
ATOM   19091 C CB  . ASN D 1 655 ? 148.884 124.738 126.444 1.00 40.98  ? 655 ASN D CB  1 
ATOM   19092 C CG  . ASN D 1 655 ? 148.960 125.881 127.440 1.00 45.38  ? 655 ASN D CG  1 
ATOM   19093 O OD1 . ASN D 1 655 ? 148.539 125.793 128.580 1.00 50.39  ? 655 ASN D OD1 1 
ATOM   19094 N ND2 . ASN D 1 655 ? 149.472 127.016 127.032 1.00 44.54  ? 655 ASN D ND2 1 
ATOM   19095 N N   . SER D 1 656 ? 148.072 122.382 129.161 1.00 42.05  ? 656 SER D N   1 
ATOM   19096 C CA  . SER D 1 656 ? 148.642 121.804 130.379 1.00 38.78  ? 656 SER D CA  1 
ATOM   19097 C C   . SER D 1 656 ? 149.338 120.459 130.152 1.00 37.66  ? 656 SER D C   1 
ATOM   19098 O O   . SER D 1 656 ? 150.362 120.205 130.779 1.00 41.50  ? 656 SER D O   1 
ATOM   19099 C CB  . SER D 1 656 ? 147.562 121.684 131.454 1.00 37.31  ? 656 SER D CB  1 
ATOM   19100 O OG  . SER D 1 656 ? 146.505 120.886 130.986 1.00 45.08  ? 656 SER D OG  1 
ATOM   19101 N N   . TRP D 1 657 ? 148.870 119.634 129.205 1.00 28.79  ? 657 TRP D N   1 
ATOM   19102 C CA  . TRP D 1 657 ? 149.558 118.399 128.795 1.00 25.07  ? 657 TRP D CA  1 
ATOM   19103 C C   . TRP D 1 657 ? 150.957 118.671 128.228 1.00 28.34  ? 657 TRP D C   1 
ATOM   19104 O O   . TRP D 1 657 ? 151.921 118.026 128.627 1.00 34.27  ? 657 TRP D O   1 
ATOM   19105 C CB  . TRP D 1 657 ? 148.689 117.623 127.801 1.00 21.15  ? 657 TRP D CB  1 
ATOM   19106 C CG  . TRP D 1 657 ? 149.322 116.390 127.228 1.00 26.85  ? 657 TRP D CG  1 
ATOM   19107 C CD1 . TRP D 1 657 ? 149.234 115.142 127.746 1.00 27.87  ? 657 TRP D CD1 1 
ATOM   19108 C CD2 . TRP D 1 657 ? 150.138 116.254 126.031 1.00 30.03  ? 657 TRP D CD2 1 
ATOM   19109 N NE1 . TRP D 1 657 ? 149.972 114.264 126.983 1.00 29.05  ? 657 TRP D NE1 1 
ATOM   19110 C CE2 . TRP D 1 657 ? 150.559 114.897 125.910 1.00 31.31  ? 657 TRP D CE2 1 
ATOM   19111 C CE3 . TRP D 1 657 ? 150.531 117.133 124.995 1.00 24.84  ? 657 TRP D CE3 1 
ATOM   19112 C CZ2 . TRP D 1 657 ? 151.351 114.443 124.852 1.00 29.13  ? 657 TRP D CZ2 1 
ATOM   19113 C CZ3 . TRP D 1 657 ? 151.303 116.680 123.918 1.00 28.94  ? 657 TRP D CZ3 1 
ATOM   19114 C CH2 . TRP D 1 657 ? 151.736 115.345 123.848 1.00 31.67  ? 657 TRP D CH2 1 
ATOM   19115 N N   . SER D 1 658 ? 151.096 119.675 127.365 1.00 33.66  ? 658 SER D N   1 
ATOM   19116 C CA  . SER D 1 658 ? 152.375 120.085 126.789 1.00 21.31  ? 658 SER D CA  1 
ATOM   19117 C C   . SER D 1 658 ? 153.331 120.642 127.841 1.00 25.95  ? 658 SER D C   1 
ATOM   19118 O O   . SER D 1 658 ? 154.514 120.312 127.853 1.00 31.89  ? 658 SER D O   1 
ATOM   19119 C CB  . SER D 1 658 ? 152.154 121.163 125.723 1.00 27.71  ? 658 SER D CB  1 
ATOM   19120 O OG  . SER D 1 658 ? 151.178 120.742 124.792 1.00 41.52  ? 658 SER D OG  1 
ATOM   19121 N N   . ILE D 1 659 ? 152.838 121.476 128.760 1.00 29.32  ? 659 ILE D N   1 
ATOM   19122 C CA  . ILE D 1 659 ? 153.656 122.042 129.842 1.00 31.60  ? 659 ILE D CA  1 
ATOM   19123 C C   . ILE D 1 659 ? 154.115 120.949 130.819 1.00 21.00  ? 659 ILE D C   1 
ATOM   19124 O O   . ILE D 1 659 ? 155.254 120.969 131.271 1.00 23.27  ? 659 ILE D O   1 
ATOM   19125 C CB  . ILE D 1 659 ? 152.894 123.191 130.528 1.00 28.00  ? 659 ILE D CB  1 
ATOM   19126 C CG1 . ILE D 1 659 ? 152.746 124.393 129.581 1.00 26.93  ? 659 ILE D CG1 1 
ATOM   19127 C CG2 . ILE D 1 659 ? 153.580 123.633 131.832 1.00 27.78  ? 659 ILE D CG2 1 
ATOM   19128 C CD1 . ILE D 1 659 ? 151.724 125.424 130.047 1.00 27.73  ? 659 ILE D CD1 1 
ATOM   19129 N N   . TRP D 1 660 ? 153.297 119.937 131.086 1.00 17.28  ? 660 TRP D N   1 
ATOM   19130 C CA  . TRP D 1 660 ? 153.716 118.743 131.807 1.00 10.55  ? 660 TRP D CA  1 
ATOM   19131 C C   . TRP D 1 660 ? 154.744 117.889 131.044 1.00 22.08  ? 660 TRP D C   1 
ATOM   19132 O O   . TRP D 1 660 ? 155.724 117.441 131.635 1.00 29.40  ? 660 TRP D O   1 
ATOM   19133 C CB  . TRP D 1 660 ? 152.474 117.948 132.186 1.00 17.93  ? 660 TRP D CB  1 
ATOM   19134 C CG  . TRP D 1 660 ? 152.755 116.583 132.709 1.00 26.63  ? 660 TRP D CG  1 
ATOM   19135 C CD1 . TRP D 1 660 ? 153.377 116.293 133.870 1.00 15.35  ? 660 TRP D CD1 1 
ATOM   19136 C CD2 . TRP D 1 660 ? 152.534 115.313 132.039 1.00 23.18  ? 660 TRP D CD2 1 
ATOM   19137 N NE1 . TRP D 1 660 ? 153.488 114.926 133.995 1.00 16.84  ? 660 TRP D NE1 1 
ATOM   19138 C CE2 . TRP D 1 660 ? 152.963 114.274 132.906 1.00 21.55  ? 660 TRP D CE2 1 
ATOM   19139 C CE3 . TRP D 1 660 ? 152.007 114.940 130.786 1.00 25.93  ? 660 TRP D CE3 1 
ATOM   19140 C CZ2 . TRP D 1 660 ? 152.819 112.921 132.573 1.00 19.79  ? 660 TRP D CZ2 1 
ATOM   19141 C CZ3 . TRP D 1 660 ? 151.890 113.590 130.428 1.00 28.74  ? 660 TRP D CZ3 1 
ATOM   19142 C CH2 . TRP D 1 660 ? 152.289 112.582 131.320 1.00 28.98  ? 660 TRP D CH2 1 
ATOM   19143 N N   . LYS D 1 661 ? 154.617 117.711 129.723 1.00 26.49  ? 661 LYS D N   1 
ATOM   19144 C CA  . LYS D 1 661 ? 155.660 117.059 128.910 1.00 12.24  ? 661 LYS D CA  1 
ATOM   19145 C C   . LYS D 1 661 ? 156.986 117.820 128.959 1.00 13.22  ? 661 LYS D C   1 
ATOM   19146 O O   . LYS D 1 661 ? 158.036 117.188 128.991 1.00 23.78  ? 661 LYS D O   1 
ATOM   19147 C CB  . LYS D 1 661 ? 155.196 116.879 127.456 1.00 18.81  ? 661 LYS D CB  1 
ATOM   19148 C CG  . LYS D 1 661 ? 154.134 115.800 127.232 1.00 13.68  ? 661 LYS D CG  1 
ATOM   19149 C CD  . LYS D 1 661 ? 154.560 114.401 127.688 1.00 16.52  ? 661 LYS D CD  1 
ATOM   19150 C CE  . LYS D 1 661 ? 153.598 113.370 127.097 1.00 27.22  ? 661 LYS D CE  1 
ATOM   19151 N NZ  . LYS D 1 661 ? 153.840 111.998 127.611 1.00 30.44  ? 661 LYS D NZ  1 
ATOM   19152 N N   . LEU D 1 662 ? 156.971 119.147 129.056 1.00 16.36  ? 662 LEU D N   1 
ATOM   19153 C CA  . LEU D 1 662 ? 158.165 119.953 129.313 1.00 12.57  ? 662 LEU D CA  1 
ATOM   19154 C C   . LEU D 1 662 ? 158.734 119.758 130.730 1.00 15.77  ? 662 LEU D C   1 
ATOM   19155 O O   . LEU D 1 662 ? 159.944 119.649 130.879 1.00 28.76  ? 662 LEU D O   1 
ATOM   19156 C CB  . LEU D 1 662 ? 157.852 121.419 128.984 1.00 16.98  ? 662 LEU D CB  1 
ATOM   19157 C CG  . LEU D 1 662 ? 159.007 122.405 129.219 1.00 20.55  ? 662 LEU D CG  1 
ATOM   19158 C CD1 . LEU D 1 662 ? 160.193 122.167 128.296 1.00 16.72  ? 662 LEU D CD1 1 
ATOM   19159 C CD2 . LEU D 1 662 ? 158.503 123.812 128.983 1.00 14.86  ? 662 LEU D CD2 1 
ATOM   19160 N N   . GLN D 1 663 ? 157.909 119.632 131.768 1.00 25.38  ? 663 GLN D N   1 
ATOM   19161 C CA  . GLN D 1 663 ? 158.379 119.278 133.115 1.00 9.62   ? 663 GLN D CA  1 
ATOM   19162 C C   . GLN D 1 663 ? 159.064 117.913 133.155 1.00 15.61  ? 663 GLN D C   1 
ATOM   19163 O O   . GLN D 1 663 ? 160.139 117.782 133.742 1.00 25.43  ? 663 GLN D O   1 
ATOM   19164 C CB  . GLN D 1 663 ? 157.219 119.269 134.109 1.00 15.15  ? 663 GLN D CB  1 
ATOM   19165 C CG  . GLN D 1 663 ? 156.675 120.658 134.419 1.00 12.53  ? 663 GLN D CG  1 
ATOM   19166 C CD  . GLN D 1 663 ? 155.486 120.591 135.360 1.00 16.31  ? 663 GLN D CD  1 
ATOM   19167 O OE1 . GLN D 1 663 ? 154.964 119.535 135.668 1.00 30.67  ? 663 GLN D OE1 1 
ATOM   19168 N NE2 . GLN D 1 663 ? 155.037 121.713 135.857 1.00 24.77  ? 663 GLN D NE2 1 
ATOM   19169 N N   . LYS D 1 664 ? 158.477 116.908 132.495 1.00 24.83  ? 664 LYS D N   1 
ATOM   19170 C CA  . LYS D 1 664 ? 159.101 115.597 132.289 1.00 4.45   ? 664 LYS D CA  1 
ATOM   19171 C C   . LYS D 1 664 ? 160.411 115.691 131.519 1.00 17.62  ? 664 LYS D C   1 
ATOM   19172 O O   . LYS D 1 664 ? 161.369 115.063 131.935 1.00 34.20  ? 664 LYS D O   1 
ATOM   19173 C CB  . LYS D 1 664 ? 158.134 114.637 131.596 1.00 15.21  ? 664 LYS D CB  1 
ATOM   19174 C CG  . LYS D 1 664 ? 157.116 114.056 132.575 1.00 15.92  ? 664 LYS D CG  1 
ATOM   19175 C CD  . LYS D 1 664 ? 156.408 112.845 131.965 1.00 17.77  ? 664 LYS D CD  1 
ATOM   19176 C CE  . LYS D 1 664 ? 155.870 111.983 133.111 1.00 33.85  ? 664 LYS D CE  1 
ATOM   19177 N NZ  . LYS D 1 664 ? 155.338 110.679 132.625 1.00 37.07  ? 664 LYS D NZ  1 
ATOM   19178 N N   . ALA D 1 665 ? 160.493 116.508 130.471 1.00 20.17  ? 665 ALA D N   1 
ATOM   19179 C CA  . ALA D 1 665 ? 161.719 116.738 129.715 1.00 7.71   ? 665 ALA D CA  1 
ATOM   19180 C C   . ALA D 1 665 ? 162.840 117.323 130.579 1.00 16.96  ? 665 ALA D C   1 
ATOM   19181 O O   . ALA D 1 665 ? 163.943 116.793 130.581 1.00 26.32  ? 665 ALA D O   1 
ATOM   19182 C CB  . ALA D 1 665 ? 161.407 117.629 128.510 1.00 10.43  ? 665 ALA D CB  1 
ATOM   19183 N N   . ILE D 1 666 ? 162.567 118.363 131.365 1.00 18.55  ? 666 ILE D N   1 
ATOM   19184 C CA  . ILE D 1 666 ? 163.529 118.971 132.296 1.00 20.00  ? 666 ILE D CA  1 
ATOM   19185 C C   . ILE D 1 666 ? 164.001 117.958 133.347 1.00 18.44  ? 666 ILE D C   1 
ATOM   19186 O O   . ILE D 1 666 ? 165.194 117.831 133.599 1.00 27.29  ? 666 ILE D O   1 
ATOM   19187 C CB  . ILE D 1 666 ? 162.889 120.228 132.932 1.00 18.56  ? 666 ILE D CB  1 
ATOM   19188 C CG1 . ILE D 1 666 ? 162.760 121.343 131.877 1.00 20.01  ? 666 ILE D CG1 1 
ATOM   19189 C CG2 . ILE D 1 666 ? 163.681 120.743 134.140 1.00 22.12  ? 666 ILE D CG2 1 
ATOM   19190 C CD1 . ILE D 1 666 ? 161.698 122.386 132.219 1.00 27.66  ? 666 ILE D CD1 1 
ATOM   19191 N N   . SER D 1 667 ? 163.049 117.238 133.947 1.00 25.73  ? 667 SER D N   1 
ATOM   19192 C CA  . SER D 1 667 ? 163.402 116.207 134.958 1.00 19.55  ? 667 SER D CA  1 
ATOM   19193 C C   . SER D 1 667 ? 164.339 115.172 134.330 1.00 18.07  ? 667 SER D C   1 
ATOM   19194 O O   . SER D 1 667 ? 165.389 114.880 134.935 1.00 31.07  ? 667 SER D O   1 
ATOM   19195 C CB  . SER D 1 667 ? 162.164 115.556 135.518 1.00 19.35  ? 667 SER D CB  1 
ATOM   19196 O OG  . SER D 1 667 ? 162.507 114.502 136.405 1.00 40.37  ? 667 SER D OG  1 
ATOM   19197 N N   . VAL D 1 668 ? 163.968 114.644 133.160 1.00 19.77  ? 668 VAL D N   1 
ATOM   19198 C CA  . VAL D 1 668 ? 164.796 113.602 132.479 1.00 20.02  ? 668 VAL D CA  1 
ATOM   19199 C C   . VAL D 1 668 ? 166.186 114.175 132.188 1.00 21.86  ? 668 VAL D C   1 
ATOM   19200 O O   . VAL D 1 668 ? 167.177 113.563 132.635 1.00 32.11  ? 668 VAL D O   1 
ATOM   19201 C CB  . VAL D 1 668 ? 164.117 113.103 131.189 1.00 22.81  ? 668 VAL D CB  1 
ATOM   19202 C CG1 . VAL D 1 668 ? 165.089 112.352 130.292 1.00 28.11  ? 668 VAL D CG1 1 
ATOM   19203 C CG2 . VAL D 1 668 ? 162.891 112.253 131.486 1.00 19.96  ? 668 VAL D CG2 1 
ATOM   19204 N N   . LEU D 1 669 ? 166.257 115.300 131.470 1.00 26.68  ? 669 LEU D N   1 
ATOM   19205 C CA  . LEU D 1 669 ? 167.549 115.857 131.093 1.00 21.37  ? 669 LEU D CA  1 
ATOM   19206 C C   . LEU D 1 669 ? 168.448 116.107 132.307 1.00 27.76  ? 669 LEU D C   1 
ATOM   19207 O O   . LEU D 1 669 ? 169.665 116.072 132.173 1.00 34.29  ? 669 LEU D O   1 
ATOM   19208 C CB  . LEU D 1 669 ? 167.313 117.128 130.269 1.00 24.50  ? 669 LEU D CB  1 
ATOM   19209 C CG  . LEU D 1 669 ? 166.664 116.836 128.904 1.00 25.97  ? 669 LEU D CG  1 
ATOM   19210 C CD1 . LEU D 1 669 ? 166.066 118.106 128.320 1.00 24.15  ? 669 LEU D CD1 1 
ATOM   19211 C CD2 . LEU D 1 669 ? 167.669 116.286 127.903 1.00 26.69  ? 669 LEU D CD2 1 
ATOM   19212 N N   . GLU D 1 670 ? 167.882 116.297 133.500 1.00 35.20  ? 670 GLU D N   1 
ATOM   19213 C CA  . GLU D 1 670 ? 168.627 116.289 134.755 1.00 22.19  ? 670 GLU D CA  1 
ATOM   19214 C C   . GLU D 1 670 ? 169.027 114.883 135.213 1.00 31.54  ? 670 GLU D C   1 
ATOM   19215 O O   . GLU D 1 670 ? 170.208 114.645 135.459 1.00 37.59  ? 670 GLU D O   1 
ATOM   19216 C CB  . GLU D 1 670 ? 167.821 117.019 135.837 1.00 30.07  ? 670 GLU D CB  1 
ATOM   19217 C CG  . GLU D 1 670 ? 168.014 118.534 135.734 1.00 36.49  ? 670 GLU D CG  1 
ATOM   19218 C CD  . GLU D 1 670 ? 169.484 118.917 135.939 1.00 43.32  ? 670 GLU D CD  1 
ATOM   19219 O OE1 . GLU D 1 670 ? 170.102 118.450 136.918 1.00 43.48  ? 670 GLU D OE1 1 
ATOM   19220 O OE2 . GLU D 1 670 ? 170.063 119.650 135.106 1.00 44.29  ? 670 GLU D OE2 1 
ATOM   19221 N N   . MET D 1 671 ? 168.084 113.938 135.273 1.00 30.15  ? 671 MET D N   1 
ATOM   19222 C CA  . MET D 1 671 ? 168.345 112.550 135.662 1.00 23.28  ? 671 MET D CA  1 
ATOM   19223 C C   . MET D 1 671 ? 169.361 111.829 134.773 1.00 32.08  ? 671 MET D C   1 
ATOM   19224 O O   . MET D 1 671 ? 170.117 111.003 135.273 1.00 35.75  ? 671 MET D O   1 
ATOM   19225 C CB  . MET D 1 671 ? 167.046 111.749 135.659 1.00 26.41  ? 671 MET D CB  1 
ATOM   19226 C CG  . MET D 1 671 ? 166.143 112.073 136.841 1.00 27.40  ? 671 MET D CG  1 
ATOM   19227 S SD  . MET D 1 671 ? 164.774 110.913 136.988 1.00 31.61  ? 671 MET D SD  1 
ATOM   19228 C CE  . MET D 1 671 ? 163.764 111.359 135.559 1.00 24.18  ? 671 MET D CE  1 
ATOM   19229 N N   . GLU D 1 672 ? 169.429 112.143 133.478 1.00 34.85  ? 672 GLU D N   1 
ATOM   19230 C CA  . GLU D 1 672 ? 170.421 111.579 132.561 1.00 27.38  ? 672 GLU D CA  1 
ATOM   19231 C C   . GLU D 1 672 ? 171.877 111.866 132.966 1.00 34.76  ? 672 GLU D C   1 
ATOM   19232 O O   . GLU D 1 672 ? 172.749 111.073 132.616 1.00 36.70  ? 672 GLU D O   1 
ATOM   19233 C CB  . GLU D 1 672 ? 170.186 112.098 131.137 1.00 34.24  ? 672 GLU D CB  1 
ATOM   19234 C CG  . GLU D 1 672 ? 169.099 111.317 130.399 1.00 32.34  ? 672 GLU D CG  1 
ATOM   19235 C CD  . GLU D 1 672 ? 169.018 111.726 128.924 1.00 40.21  ? 672 GLU D CD  1 
ATOM   19236 O OE1 . GLU D 1 672 ? 168.914 112.930 128.618 1.00 37.22  ? 672 GLU D OE1 1 
ATOM   19237 O OE2 . GLU D 1 672 ? 169.105 110.843 128.043 1.00 49.10  ? 672 GLU D OE2 1 
ATOM   19238 N N   . ASN D 1 673 ? 172.155 112.938 133.717 1.00 40.12  ? 673 ASN D N   1 
ATOM   19239 C CA  . ASN D 1 673 ? 173.491 113.225 134.266 1.00 39.97  ? 673 ASN D CA  1 
ATOM   19240 C C   . ASN D 1 673 ? 173.847 112.372 135.498 1.00 41.63  ? 673 ASN D C   1 
ATOM   19241 O O   . ASN D 1 673 ? 175.000 112.356 135.925 1.00 46.28  ? 673 ASN D O   1 
ATOM   19242 C CB  . ASN D 1 673 ? 173.591 114.713 134.640 1.00 37.24  ? 673 ASN D CB  1 
ATOM   19243 C CG  . ASN D 1 673 ? 173.284 115.646 133.490 1.00 40.21  ? 673 ASN D CG  1 
ATOM   19244 O OD1 . ASN D 1 673 ? 173.801 115.518 132.391 1.00 43.54  ? 673 ASN D OD1 1 
ATOM   19245 N ND2 . ASN D 1 673 ? 172.430 116.610 133.699 1.00 42.89  ? 673 ASN D ND2 1 
ATOM   19246 N N   . GLY D 1 674 ? 172.873 111.684 136.100 1.00 37.14  ? 674 GLY D N   1 
ATOM   19247 C CA  . GLY D 1 674 ? 173.012 111.027 137.393 1.00 36.85  ? 674 GLY D CA  1 
ATOM   19248 C C   . GLY D 1 674 ? 173.120 112.014 138.553 1.00 32.26  ? 674 GLY D C   1 
ATOM   19249 O O   . GLY D 1 674 ? 172.660 113.150 138.477 1.00 38.21  ? 674 GLY D O   1 
ATOM   19250 N N   . TYR D 1 675 ? 173.706 111.568 139.653 1.00 37.80  ? 675 TYR D N   1 
ATOM   19251 C CA  . TYR D 1 675 ? 173.844 112.349 140.884 1.00 39.83  ? 675 TYR D CA  1 
ATOM   19252 C C   . TYR D 1 675 ? 175.161 113.131 140.958 1.00 37.77  ? 675 TYR D C   1 
ATOM   19253 O O   . TYR D 1 675 ? 176.141 112.755 140.311 1.00 48.94  ? 675 TYR D O   1 
ATOM   19254 C CB  . TYR D 1 675 ? 173.693 111.405 142.076 1.00 33.74  ? 675 TYR D CB  1 
ATOM   19255 C CG  . TYR D 1 675 ? 172.433 110.568 142.045 1.00 34.83  ? 675 TYR D CG  1 
ATOM   19256 C CD1 . TYR D 1 675 ? 171.178 111.197 142.145 1.00 33.98  ? 675 TYR D CD1 1 
ATOM   19257 C CD2 . TYR D 1 675 ? 172.507 109.173 141.915 1.00 39.07  ? 675 TYR D CD2 1 
ATOM   19258 C CE1 . TYR D 1 675 ? 170.001 110.435 142.106 1.00 32.58  ? 675 TYR D CE1 1 
ATOM   19259 C CE2 . TYR D 1 675 ? 171.328 108.405 141.893 1.00 38.54  ? 675 TYR D CE2 1 
ATOM   19260 C CZ  . TYR D 1 675 ? 170.075 109.034 141.985 1.00 34.97  ? 675 TYR D CZ  1 
ATOM   19261 O OH  . TYR D 1 675 ? 168.945 108.284 141.960 1.00 34.66  ? 675 TYR D OH  1 
ATOM   19262 N N   . TRP D 1 676 ? 175.226 114.160 141.804 1.00 33.06  ? 676 TRP D N   1 
ATOM   19263 C CA  . TRP D 1 676 ? 176.409 115.021 141.958 1.00 32.98  ? 676 TRP D CA  1 
ATOM   19264 C C   . TRP D 1 676 ? 177.683 114.240 142.317 1.00 36.33  ? 676 TRP D C   1 
ATOM   19265 O O   . TRP D 1 676 ? 178.773 114.597 141.875 1.00 45.04  ? 676 TRP D O   1 
ATOM   19266 C CB  . TRP D 1 676 ? 176.113 116.114 143.000 1.00 34.51  ? 676 TRP D CB  1 
ATOM   19267 C CG  . TRP D 1 676 ? 175.882 115.678 144.417 1.00 34.40  ? 676 TRP D CG  1 
ATOM   19268 C CD1 . TRP D 1 676 ? 174.681 115.406 144.970 1.00 35.81  ? 676 TRP D CD1 1 
ATOM   19269 C CD2 . TRP D 1 676 ? 176.862 115.425 145.471 1.00 37.28  ? 676 TRP D CD2 1 
ATOM   19270 N NE1 . TRP D 1 676 ? 174.845 115.012 146.280 1.00 33.64  ? 676 TRP D NE1 1 
ATOM   19271 C CE2 . TRP D 1 676 ? 176.172 114.968 146.631 1.00 35.62  ? 676 TRP D CE2 1 
ATOM   19272 C CE3 . TRP D 1 676 ? 178.268 115.507 145.559 1.00 38.08  ? 676 TRP D CE3 1 
ATOM   19273 C CZ2 . TRP D 1 676 ? 176.838 114.583 147.799 1.00 40.63  ? 676 TRP D CZ2 1 
ATOM   19274 C CZ3 . TRP D 1 676 ? 178.947 115.119 146.728 1.00 36.13  ? 676 TRP D CZ3 1 
ATOM   19275 C CH2 . TRP D 1 676 ? 178.238 114.647 147.841 1.00 40.41  ? 676 TRP D CH2 1 
ATOM   19276 N N   . TRP D 1 677 ? 177.543 113.150 143.065 1.00 36.99  ? 677 TRP D N   1 
ATOM   19277 C CA  . TRP D 1 677 ? 178.607 112.249 143.505 1.00 36.20  ? 677 TRP D CA  1 
ATOM   19278 C C   . TRP D 1 677 ? 178.868 111.068 142.555 1.00 41.49  ? 677 TRP D C   1 
ATOM   19279 O O   . TRP D 1 677 ? 179.881 110.388 142.708 1.00 45.96  ? 677 TRP D O   1 
ATOM   19280 C CB  . TRP D 1 677 ? 178.205 111.731 144.892 1.00 38.41  ? 677 TRP D CB  1 
ATOM   19281 C CG  . TRP D 1 677 ? 176.918 110.971 144.921 1.00 36.04  ? 677 TRP D CG  1 
ATOM   19282 C CD1 . TRP D 1 677 ? 175.697 111.515 145.108 1.00 29.48  ? 677 TRP D CD1 1 
ATOM   19283 C CD2 . TRP D 1 677 ? 176.685 109.545 144.715 1.00 37.91  ? 677 TRP D CD2 1 
ATOM   19284 N NE1 . TRP D 1 677 ? 174.735 110.537 145.014 1.00 29.14  ? 677 TRP D NE1 1 
ATOM   19285 C CE2 . TRP D 1 677 ? 175.281 109.309 144.735 1.00 35.67  ? 677 TRP D CE2 1 
ATOM   19286 C CE3 . TRP D 1 677 ? 177.518 108.426 144.502 1.00 37.55  ? 677 TRP D CE3 1 
ATOM   19287 C CZ2 . TRP D 1 677 ? 174.727 108.040 144.529 1.00 37.12  ? 677 TRP D CZ2 1 
ATOM   19288 C CZ3 . TRP D 1 677 ? 176.972 107.144 144.314 1.00 40.16  ? 677 TRP D CZ3 1 
ATOM   19289 C CH2 . TRP D 1 677 ? 175.580 106.949 144.322 1.00 39.88  ? 677 TRP D CH2 1 
ATOM   19290 N N   . CYS D 1 678 ? 177.973 110.784 141.600 1.00 46.18  ? 678 CYS D N   1 
ATOM   19291 C CA  . CYS D 1 678 ? 177.997 109.558 140.792 1.00 45.03  ? 678 CYS D CA  1 
ATOM   19292 C C   . CYS D 1 678 ? 178.314 109.802 139.306 1.00 50.06  ? 678 CYS D C   1 
ATOM   19293 O O   . CYS D 1 678 ? 179.051 109.023 138.703 1.00 54.39  ? 678 CYS D O   1 
ATOM   19294 C CB  . CYS D 1 678 ? 176.666 108.822 140.984 1.00 48.15  ? 678 CYS D CB  1 
ATOM   19295 S SG  . CYS D 1 678 ? 176.790 107.129 140.344 1.00 62.86  ? 678 CYS D SG  1 
ATOM   19296 N N   . ARG D 1 679 ? 177.896 110.988 138.799 1.00 53.64  ? 679 ARG D N   1 
ATOM   19297 C CA  . ARG D 1 679 ? 178.313 111.474 137.447 1.00 55.54  ? 679 ARG D CA  1 
ATOM   19298 C C   . ARG D 1 679 ? 178.323 110.299 136.460 1.00 52.92  ? 679 ARG D C   1 
ATOM   19299 O O   . ARG D 1 679 ? 179.429 109.840 136.115 1.00 54.57  ? 679 ARG D O   1 
ATOM   19300 C CB  . ARG D 1 679 ? 179.696 112.107 137.730 1.00 57.64  ? 679 ARG D CB  1 
ATOM   19301 C CG  . ARG D 1 679 ? 179.979 113.383 136.931 1.00 56.69  ? 679 ARG D CG  1 
ATOM   19302 C CD  . ARG D 1 679 ? 179.175 114.588 137.434 1.00 55.39  ? 679 ARG D CD  1 
ATOM   19303 N NE  . ARG D 1 679 ? 179.424 114.924 138.829 1.00 55.28  ? 679 ARG D NE  1 
ATOM   19304 C CZ  . ARG D 1 679 ? 180.284 115.849 139.236 1.00 59.48  ? 679 ARG D CZ  1 
ATOM   19305 N NH1 . ARG D 1 679 ? 180.441 116.087 140.527 1.00 58.47  ? 679 ARG D NH1 1 
ATOM   19306 N NH2 . ARG D 1 679 ? 180.983 116.538 138.352 1.00 56.61  ? 679 ARG D NH2 1 
ATOM   19307 N N   . ARG D 1 680 ? 177.149 109.838 136.016 1.00 53.43  ? 680 ARG D N   1 
ATOM   19308 C CA  . ARG D 1 680 ? 176.997 108.680 135.108 1.00 53.71  ? 680 ARG D CA  1 
ATOM   19309 C C   . ARG D 1 680 ? 177.320 108.953 133.627 1.00 54.05  ? 680 ARG D C   1 
ATOM   19310 O O   . ARG D 1 680 ? 177.086 110.044 133.111 1.00 53.98  ? 680 ARG D O   1 
ATOM   19311 C CB  . ARG D 1 680 ? 175.609 108.028 135.276 1.00 52.08  ? 680 ARG D CB  1 
ATOM   19312 C CG  . ARG D 1 680 ? 174.497 108.656 134.428 1.00 48.15  ? 680 ARG D CG  1 
ATOM   19313 C CD  . ARG D 1 680 ? 173.154 107.962 134.641 1.00 48.73  ? 680 ARG D CD  1 
ATOM   19314 N NE  . ARG D 1 680 ? 172.251 108.218 133.508 1.00 57.88  ? 680 ARG D NE  1 
ATOM   19315 C CZ  . ARG D 1 680 ? 171.237 107.466 133.118 1.00 54.36  ? 680 ARG D CZ  1 
ATOM   19316 N NH1 . ARG D 1 680 ? 170.645 107.690 131.985 1.00 49.68  ? 680 ARG D NH1 1 
ATOM   19317 N NH2 . ARG D 1 680 ? 170.801 106.471 133.828 1.00 50.11  ? 680 ARG D NH2 1 
ATOM   19318 N N   . LYS D 1 681 ? 177.789 107.917 132.924 1.00 60.46  ? 681 LYS D N   1 
ATOM   19319 C CA  . LYS D 1 681 ? 178.001 107.892 131.463 1.00 62.30  ? 681 LYS D CA  1 
ATOM   19320 C C   . LYS D 1 681 ? 176.667 107.762 130.709 1.00 61.38  ? 681 LYS D C   1 
ATOM   19321 O O   . LYS D 1 681 ? 175.806 106.979 131.105 1.00 56.75  ? 681 LYS D O   1 
ATOM   19322 C CB  . LYS D 1 681 ? 178.956 106.729 131.129 1.00 62.13  ? 681 LYS D CB  1 
ATOM   19323 C CG  . LYS D 1 681 ? 179.515 106.714 129.697 1.00 63.11  ? 681 LYS D CG  1 
ATOM   19324 C CD  . LYS D 1 681 ? 180.498 107.863 129.429 1.00 64.18  ? 681 LYS D CD  1 
ATOM   19325 C CE  . LYS D 1 681 ? 181.140 107.687 128.050 1.00 64.25  ? 681 LYS D CE  1 
ATOM   19326 N NZ  . LYS D 1 681 ? 182.156 108.729 127.777 1.00 63.38  ? 681 LYS D NZ  1 
ATOM   19327 N N   . LYS D 1 682 ? 176.497 108.520 129.621 1.00 55.28  ? 682 LYS D N   1 
ATOM   19328 C CA  . LYS D 1 682 ? 175.298 108.516 128.760 1.00 56.31  ? 682 LYS D CA  1 
ATOM   19329 C C   . LYS D 1 682 ? 175.410 107.512 127.608 1.00 56.33  ? 682 LYS D C   1 
ATOM   19330 O O   . LYS D 1 682 ? 176.509 107.128 127.215 1.00 58.56  ? 682 LYS D O   1 
ATOM   19331 C CB  . LYS D 1 682 ? 175.040 109.941 128.236 1.00 53.05  ? 682 LYS D CB  1 
ATOM   19332 C CG  . LYS D 1 682 ? 174.791 110.921 129.388 1.00 51.98  ? 682 LYS D CG  1 
ATOM   19333 C CD  . LYS D 1 682 ? 174.429 112.316 128.890 1.00 52.69  ? 682 LYS D CD  1 
ATOM   19334 C CE  . LYS D 1 682 ? 174.256 113.237 130.095 1.00 53.91  ? 682 LYS D CE  1 
ATOM   19335 N NZ  . LYS D 1 682 ? 174.028 114.641 129.699 1.00 55.29  ? 682 LYS D NZ  1 
ATOM   19336 N N   . HIS D 1 683 ? 174.281 107.129 127.013 1.00 49.53  ? 683 HIS D N   1 
ATOM   19337 C CA  . HIS D 1 683 ? 174.219 106.286 125.812 1.00 51.95  ? 683 HIS D CA  1 
ATOM   19338 C C   . HIS D 1 683 ? 173.499 107.006 124.661 1.00 53.17  ? 683 HIS D C   1 
ATOM   19339 O O   . HIS D 1 683 ? 172.597 107.816 124.948 1.00 53.04  ? 683 HIS D O   1 
ATOM   19340 C CB  . HIS D 1 683 ? 173.510 104.964 126.132 1.00 55.29  ? 683 HIS D CB  1 
ATOM   19341 C CG  . HIS D 1 683 ? 172.024 105.089 126.202 1.00 55.70  ? 683 HIS D CG  1 
ATOM   19342 N ND1 . HIS D 1 683 ? 171.366 105.427 127.368 1.00 55.07  ? 683 HIS D ND1 1 
ATOM   19343 C CD2 . HIS D 1 683 ? 171.070 104.932 125.259 1.00 52.58  ? 683 HIS D CD2 1 
ATOM   19344 C CE1 . HIS D 1 683 ? 170.068 105.468 127.141 1.00 55.80  ? 683 HIS D CE1 1 
ATOM   19345 N NE2 . HIS D 1 683 ? 169.861 105.167 125.854 1.00 53.51  ? 683 HIS D NE2 1 
ATOM   19346 N N   . ARG D 1 684 ? 173.888 106.718 123.413 1.00 45.86  ? 684 ARG D N   1 
ATOM   19347 C CA  . ARG D 1 684 ? 173.204 107.240 122.222 1.00 38.72  ? 684 ARG D CA  1 
ATOM   19348 C C   . ARG D 1 684 ? 171.847 106.579 122.028 1.00 42.71  ? 684 ARG D C   1 
ATOM   19349 O O   . ARG D 1 684 ? 171.710 105.374 122.234 1.00 42.33  ? 684 ARG D O   1 
ATOM   19350 C CB  . ARG D 1 684 ? 174.037 107.029 120.953 1.00 41.19  ? 684 ARG D CB  1 
ATOM   19351 C CG  . ARG D 1 684 ? 175.355 107.789 121.016 1.00 42.45  ? 684 ARG D CG  1 
ATOM   19352 C CD  . ARG D 1 684 ? 176.025 107.932 119.655 1.00 39.06  ? 684 ARG D CD  1 
ATOM   19353 N NE  . ARG D 1 684 ? 175.352 108.958 118.842 1.00 35.80  ? 684 ARG D NE  1 
ATOM   19354 C CZ  . ARG D 1 684 ? 175.923 109.798 118.004 1.00 42.11  ? 684 ARG D CZ  1 
ATOM   19355 N NH1 . ARG D 1 684 ? 175.226 110.745 117.453 1.00 44.63  ? 684 ARG D NH1 1 
ATOM   19356 N NH2 . ARG D 1 684 ? 177.185 109.733 117.704 1.00 42.48  ? 684 ARG D NH2 1 
ATOM   19357 N N   . GLU D 1 685 ? 170.882 107.339 121.535 1.00 42.30  ? 685 GLU D N   1 
ATOM   19358 C CA  . GLU D 1 685 ? 169.588 106.815 121.112 1.00 38.72  ? 685 GLU D CA  1 
ATOM   19359 C C   . GLU D 1 685 ? 169.391 106.841 119.596 1.00 45.53  ? 685 GLU D C   1 
ATOM   19360 O O   . GLU D 1 685 ? 170.167 107.433 118.846 1.00 50.64  ? 685 GLU D O   1 
ATOM   19361 C CB  . GLU D 1 685 ? 168.469 107.496 121.900 1.00 39.49  ? 685 GLU D CB  1 
ATOM   19362 C CG  . GLU D 1 685 ? 168.566 106.973 123.338 1.00 46.41  ? 685 GLU D CG  1 
ATOM   19363 C CD  . GLU D 1 685 ? 167.561 107.634 124.262 1.00 45.56  ? 685 GLU D CD  1 
ATOM   19364 O OE1 . GLU D 1 685 ? 166.353 107.576 123.956 1.00 44.43  ? 685 GLU D OE1 1 
ATOM   19365 O OE2 . GLU D 1 685 ? 168.001 108.179 125.298 1.00 51.88  ? 685 GLU D OE2 1 
ATOM   19366 N N   . GLY D 1 686 ? 168.383 106.105 119.130 1.00 39.36  ? 686 GLY D N   1 
ATOM   19367 C CA  . GLY D 1 686 ? 168.329 105.655 117.746 1.00 37.17  ? 686 GLY D CA  1 
ATOM   19368 C C   . GLY D 1 686 ? 169.402 104.612 117.432 1.00 37.92  ? 686 GLY D C   1 
ATOM   19369 O O   . GLY D 1 686 ? 170.006 104.019 118.328 1.00 42.37  ? 686 GLY D O   1 
ATOM   19370 N N   . ARG D 1 687 ? 169.631 104.366 116.148 1.00 45.69  ? 687 ARG D N   1 
ATOM   19371 C CA  . ARG D 1 687 ? 170.630 103.433 115.615 1.00 45.41  ? 687 ARG D CA  1 
ATOM   19372 C C   . ARG D 1 687 ? 171.428 104.110 114.519 1.00 44.80  ? 687 ARG D C   1 
ATOM   19373 O O   . ARG D 1 687 ? 170.879 104.915 113.772 1.00 49.27  ? 687 ARG D O   1 
ATOM   19374 C CB  . ARG D 1 687 ? 169.952 102.175 115.058 1.00 47.02  ? 687 ARG D CB  1 
ATOM   19375 C CG  . ARG D 1 687 ? 169.329 101.293 116.144 1.00 48.17  ? 687 ARG D CG  1 
ATOM   19376 C CD  . ARG D 1 687 ? 168.717 100.017 115.556 1.00 52.84  ? 687 ARG D CD  1 
ATOM   19377 N NE  . ARG D 1 687 ? 169.735 99.149  114.931 1.00 56.40  ? 687 ARG D NE  1 
ATOM   19378 C CZ  . ARG D 1 687 ? 169.545 97.961  114.394 1.00 54.61  ? 687 ARG D CZ  1 
ATOM   19379 N NH1 . ARG D 1 687 ? 170.527 97.335  113.819 1.00 54.95  ? 687 ARG D NH1 1 
ATOM   19380 N NH2 . ARG D 1 687 ? 168.387 97.367  114.412 1.00 52.05  ? 687 ARG D NH2 1 
ATOM   19381 N N   . LEU D 1 688 ? 172.701 103.763 114.377 1.00 41.32  ? 688 LEU D N   1 
ATOM   19382 C CA  . LEU D 1 688 ? 173.483 104.134 113.199 1.00 41.24  ? 688 LEU D CA  1 
ATOM   19383 C C   . LEU D 1 688 ? 172.971 103.360 111.975 1.00 42.89  ? 688 LEU D C   1 
ATOM   19384 O O   . LEU D 1 688 ? 173.115 102.142 111.908 1.00 49.03  ? 688 LEU D O   1 
ATOM   19385 C CB  . LEU D 1 688 ? 174.967 103.873 113.489 1.00 45.49  ? 688 LEU D CB  1 
ATOM   19386 C CG  . LEU D 1 688 ? 175.918 104.255 112.349 1.00 42.36  ? 688 LEU D CG  1 
ATOM   19387 C CD1 . LEU D 1 688 ? 175.788 105.727 111.964 1.00 43.14  ? 688 LEU D CD1 1 
ATOM   19388 C CD2 . LEU D 1 688 ? 177.353 104.007 112.798 1.00 46.61  ? 688 LEU D CD2 1 
ATOM   19389 N N   . LEU D 1 689 ? 172.351 104.057 111.023 1.00 44.88  ? 689 LEU D N   1 
ATOM   19390 C CA  . LEU D 1 689 ? 171.708 103.487 109.835 1.00 47.47  ? 689 LEU D CA  1 
ATOM   19391 C C   . LEU D 1 689 ? 172.136 104.235 108.571 1.00 50.99  ? 689 LEU D C   1 
ATOM   19392 O O   . LEU D 1 689 ? 172.286 105.457 108.587 1.00 53.69  ? 689 LEU D O   1 
ATOM   19393 C CB  . LEU D 1 689 ? 170.173 103.537 109.979 1.00 46.69  ? 689 LEU D CB  1 
ATOM   19394 C CG  . LEU D 1 689 ? 169.590 102.715 111.139 1.00 52.28  ? 689 LEU D CG  1 
ATOM   19395 C CD1 . LEU D 1 689 ? 168.098 102.993 111.261 1.00 50.58  ? 689 LEU D CD1 1 
ATOM   19396 C CD2 . LEU D 1 689 ? 169.770 101.211 110.946 1.00 51.59  ? 689 LEU D CD2 1 
ATOM   19397 N N   . LYS D 1 690 ? 172.294 103.514 107.457 1.00 59.06  ? 690 LYS D N   1 
ATOM   19398 C CA  . LYS D 1 690 ? 172.458 104.109 106.125 1.00 60.16  ? 690 LYS D CA  1 
ATOM   19399 C C   . LYS D 1 690 ? 171.113 104.620 105.603 1.00 58.89  ? 690 LYS D C   1 
ATOM   19400 O O   . LYS D 1 690 ? 170.140 103.871 105.577 1.00 57.43  ? 690 LYS D O   1 
ATOM   19401 C CB  . LYS D 1 690 ? 173.094 103.088 105.168 1.00 60.92  ? 690 LYS D CB  1 
ATOM   19402 C CG  . LYS D 1 690 ? 173.453 103.723 103.816 1.00 61.74  ? 690 LYS D CG  1 
ATOM   19403 C CD  . LYS D 1 690 ? 174.035 102.682 102.857 1.00 61.97  ? 690 LYS D CD  1 
ATOM   19404 C CE  . LYS D 1 690 ? 174.212 103.286 101.466 1.00 63.99  ? 690 LYS D CE  1 
ATOM   19405 N NZ  . LYS D 1 690 ? 174.666 102.275 100.487 1.00 62.31  ? 690 LYS D NZ  1 
ATOM   19406 N N   . VAL D 1 691 ? 171.069 105.873 105.154 1.00 55.27  ? 691 VAL D N   1 
ATOM   19407 C CA  . VAL D 1 691 ? 169.863 106.526 104.608 1.00 57.78  ? 691 VAL D CA  1 
ATOM   19408 C C   . VAL D 1 691 ? 169.986 106.902 103.122 1.00 56.02  ? 691 VAL D C   1 
ATOM   19409 O O   . VAL D 1 691 ? 168.983 107.220 102.486 1.00 53.82  ? 691 VAL D O   1 
ATOM   19410 C CB  . VAL D 1 691 ? 169.438 107.734 105.471 1.00 52.48  ? 691 VAL D CB  1 
ATOM   19411 C CG1 . VAL D 1 691 ? 169.078 107.314 106.899 1.00 46.28  ? 691 VAL D CG1 1 
ATOM   19412 C CG2 . VAL D 1 691 ? 170.503 108.827 105.552 1.00 50.63  ? 691 VAL D CG2 1 
ATOM   19413 N N   . GLY D 1 692 ? 171.184 106.823 102.537 1.00 63.77  ? 692 GLY D N   1 
ATOM   19414 C CA  . GLY D 1 692 ? 171.437 107.123 101.124 1.00 64.55  ? 692 GLY D CA  1 
ATOM   19415 C C   . GLY D 1 692 ? 172.929 107.222 100.806 1.00 69.59  ? 692 GLY D C   1 
ATOM   19416 O O   . GLY D 1 692 ? 173.741 106.534 101.426 1.00 69.93  ? 692 GLY D O   1 
ATOM   19417 N N   . THR D 1 693 ? 173.306 108.110 99.879  1.00 75.77  ? 693 THR D N   1 
ATOM   19418 C CA  . THR D 1 693 ? 174.703 108.486 99.572  1.00 75.33  ? 693 THR D CA  1 
ATOM   19419 C C   . THR D 1 693 ? 174.884 110.004 99.706  1.00 74.67  ? 693 THR D C   1 
ATOM   19420 O O   . THR D 1 693 ? 173.991 110.761 99.322  1.00 75.02  ? 693 THR D O   1 
ATOM   19421 C CB  . THR D 1 693 ? 175.111 108.000 98.171  1.00 76.07  ? 693 THR D CB  1 
ATOM   19422 O OG1 . THR D 1 693 ? 174.969 106.598 98.085  1.00 75.68  ? 693 THR D OG1 1 
ATOM   19423 C CG2 . THR D 1 693 ? 176.567 108.313 97.830  1.00 75.35  ? 693 THR D CG2 1 
ATOM   19424 N N   . ARG D 1 694 ? 176.006 110.466 100.276 1.00 77.02  ? 694 ARG D N   1 
ATOM   19425 C CA  . ARG D 1 694 ? 176.208 111.881 100.648 1.00 78.69  ? 694 ARG D CA  1 
ATOM   19426 C C   . ARG D 1 694 ? 176.305 112.812 99.432  1.00 80.35  ? 694 ARG D C   1 
ATOM   19427 O O   . ARG D 1 694 ? 176.778 112.418 98.365  1.00 78.44  ? 694 ARG D O   1 
ATOM   19428 C CB  . ARG D 1 694 ? 177.452 112.043 101.541 1.00 77.78  ? 694 ARG D CB  1 
ATOM   19429 C CG  . ARG D 1 694 ? 177.354 111.235 102.842 1.00 77.72  ? 694 ARG D CG  1 
ATOM   19430 C CD  . ARG D 1 694 ? 178.539 111.497 103.777 1.00 78.66  ? 694 ARG D CD  1 
ATOM   19431 N NE  . ARG D 1 694 ? 178.462 112.828 104.407 1.00 81.21  ? 694 ARG D NE  1 
ATOM   19432 C CZ  . ARG D 1 694 ? 179.376 113.386 105.178 1.00 81.40  ? 694 ARG D CZ  1 
ATOM   19433 N NH1 . ARG D 1 694 ? 179.167 114.559 105.697 1.00 78.98  ? 694 ARG D NH1 1 
ATOM   19434 N NH2 . ARG D 1 694 ? 180.508 112.806 105.449 1.00 78.90  ? 694 ARG D NH2 1 
ATOM   19435 N N   . GLY D 1 695 ? 175.899 114.067 99.611  1.00 78.83  ? 695 GLY D N   1 
ATOM   19436 C CA  . GLY D 1 695 ? 175.954 115.096 98.571  1.00 78.52  ? 695 GLY D CA  1 
ATOM   19437 C C   . GLY D 1 695 ? 175.290 116.409 98.981  1.00 78.43  ? 695 GLY D C   1 
ATOM   19438 O O   . GLY D 1 695 ? 174.459 116.448 99.894  1.00 77.61  ? 695 GLY D O   1 
ATOM   19439 N N   . PRO D 1 699 ? 178.733 106.401 101.476 1.00 77.00  ? 699 PRO D N   1 
ATOM   19440 C CA  . PRO D 1 699 ? 177.415 106.201 102.060 1.00 78.11  ? 699 PRO D CA  1 
ATOM   19441 C C   . PRO D 1 699 ? 177.057 107.286 103.086 1.00 77.42  ? 699 PRO D C   1 
ATOM   19442 O O   . PRO D 1 699 ? 177.914 107.807 103.801 1.00 74.98  ? 699 PRO D O   1 
ATOM   19443 C CB  . PRO D 1 699 ? 177.468 104.813 102.699 1.00 76.40  ? 699 PRO D CB  1 
ATOM   19444 C CG  . PRO D 1 699 ? 178.938 104.660 103.074 1.00 75.94  ? 699 PRO D CG  1 
ATOM   19445 C CD  . PRO D 1 699 ? 179.653 105.383 101.939 1.00 76.68  ? 699 PRO D CD  1 
ATOM   19446 N N   . ASP D 1 700 ? 175.769 107.619 103.170 1.00 67.57  ? 700 ASP D N   1 
ATOM   19447 C CA  . ASP D 1 700 ? 175.210 108.536 104.169 1.00 67.15  ? 700 ASP D CA  1 
ATOM   19448 C C   . ASP D 1 700 ? 174.685 107.732 105.364 1.00 66.10  ? 700 ASP D C   1 
ATOM   19449 O O   . ASP D 1 700 ? 173.593 107.165 105.307 1.00 64.84  ? 700 ASP D O   1 
ATOM   19450 C CB  . ASP D 1 700 ? 174.119 109.392 103.503 1.00 66.65  ? 700 ASP D CB  1 
ATOM   19451 C CG  . ASP D 1 700 ? 173.574 110.523 104.379 1.00 69.39  ? 700 ASP D CG  1 
ATOM   19452 O OD1 . ASP D 1 700 ? 174.021 110.707 105.529 1.00 66.68  ? 700 ASP D OD1 1 
ATOM   19453 O OD2 . ASP D 1 700 ? 172.699 111.271 103.896 1.00 67.74  ? 700 ASP D OD2 1 
ATOM   19454 N N   . GLU D 1 701 ? 175.491 107.617 106.420 1.00 61.62  ? 701 GLU D N   1 
ATOM   19455 C CA  . GLU D 1 701 ? 175.144 106.906 107.653 1.00 61.01  ? 701 GLU D CA  1 
ATOM   19456 C C   . GLU D 1 701 ? 174.916 107.883 108.805 1.00 59.21  ? 701 GLU D C   1 
ATOM   19457 O O   . GLU D 1 701 ? 175.759 108.741 109.073 1.00 61.25  ? 701 GLU D O   1 
ATOM   19458 C CB  . GLU D 1 701 ? 176.226 105.884 108.028 1.00 62.17  ? 701 GLU D CB  1 
ATOM   19459 C CG  . GLU D 1 701 ? 176.332 104.738 107.018 1.00 62.52  ? 701 GLU D CG  1 
ATOM   19460 C CD  . GLU D 1 701 ? 177.229 103.606 107.537 1.00 64.57  ? 701 GLU D CD  1 
ATOM   19461 O OE1 . GLU D 1 701 ? 178.375 103.875 107.954 1.00 63.18  ? 701 GLU D OE1 1 
ATOM   19462 O OE2 . GLU D 1 701 ? 176.799 102.435 107.516 1.00 62.51  ? 701 GLU D OE2 1 
ATOM   19463 N N   . ARG D 1 702 ? 173.790 107.746 109.507 1.00 48.02  ? 702 ARG D N   1 
ATOM   19464 C CA  . ARG D 1 702 ? 173.362 108.662 110.574 1.00 39.04  ? 702 ARG D CA  1 
ATOM   19465 C C   . ARG D 1 702 ? 172.751 107.930 111.747 1.00 38.77  ? 702 ARG D C   1 
ATOM   19466 O O   . ARG D 1 702 ? 172.164 106.870 111.581 1.00 44.04  ? 702 ARG D O   1 
ATOM   19467 C CB  . ARG D 1 702 ? 172.318 109.650 110.047 1.00 40.84  ? 702 ARG D CB  1 
ATOM   19468 C CG  . ARG D 1 702 ? 172.753 110.359 108.772 1.00 43.13  ? 702 ARG D CG  1 
ATOM   19469 C CD  . ARG D 1 702 ? 171.815 111.519 108.519 1.00 40.16  ? 702 ARG D CD  1 
ATOM   19470 N NE  . ARG D 1 702 ? 171.983 112.022 107.163 1.00 41.94  ? 702 ARG D NE  1 
ATOM   19471 C CZ  . ARG D 1 702 ? 171.277 112.983 106.621 1.00 40.72  ? 702 ARG D CZ  1 
ATOM   19472 N NH1 . ARG D 1 702 ? 171.329 113.148 105.343 1.00 39.35  ? 702 ARG D NH1 1 
ATOM   19473 N NH2 . ARG D 1 702 ? 170.501 113.761 107.320 1.00 41.77  ? 702 ARG D NH2 1 
ATOM   19474 N N   . TRP D 1 703 ? 172.840 108.530 112.925 1.00 41.81  ? 703 TRP D N   1 
ATOM   19475 C CA  . TRP D 1 703 ? 172.067 108.110 114.087 1.00 38.11  ? 703 TRP D CA  1 
ATOM   19476 C C   . TRP D 1 703 ? 170.618 108.550 113.917 1.00 35.52  ? 703 TRP D C   1 
ATOM   19477 O O   . TRP D 1 703 ? 170.284 109.731 113.977 1.00 34.30  ? 703 TRP D O   1 
ATOM   19478 C CB  . TRP D 1 703 ? 172.719 108.628 115.360 1.00 37.41  ? 703 TRP D CB  1 
ATOM   19479 C CG  . TRP D 1 703 ? 173.948 107.849 115.689 1.00 37.16  ? 703 TRP D CG  1 
ATOM   19480 C CD1 . TRP D 1 703 ? 175.179 108.049 115.166 1.00 38.88  ? 703 TRP D CD1 1 
ATOM   19481 C CD2 . TRP D 1 703 ? 174.063 106.665 116.527 1.00 39.16  ? 703 TRP D CD2 1 
ATOM   19482 N NE1 . TRP D 1 703 ? 176.043 107.082 115.630 1.00 40.56  ? 703 TRP D NE1 1 
ATOM   19483 C CE2 . TRP D 1 703 ? 175.409 106.199 116.471 1.00 38.91  ? 703 TRP D CE2 1 
ATOM   19484 C CE3 . TRP D 1 703 ? 173.169 105.945 117.348 1.00 37.66  ? 703 TRP D CE3 1 
ATOM   19485 C CZ2 . TRP D 1 703 ? 175.846 105.077 117.185 1.00 35.37  ? 703 TRP D CZ2 1 
ATOM   19486 C CZ3 . TRP D 1 703 ? 173.599 104.824 118.079 1.00 38.85  ? 703 TRP D CZ3 1 
ATOM   19487 C CH2 . TRP D 1 703 ? 174.934 104.390 117.998 1.00 40.49  ? 703 TRP D CH2 1 
ATOM   19488 N N   . CYS D 1 704 ? 169.771 107.568 113.652 1.00 39.05  ? 704 CYS D N   1 
ATOM   19489 C CA  . CYS D 1 704 ? 168.391 107.750 113.249 1.00 32.65  ? 704 CYS D CA  1 
ATOM   19490 C C   . CYS D 1 704 ? 167.457 107.065 114.235 1.00 30.99  ? 704 CYS D C   1 
ATOM   19491 O O   . CYS D 1 704 ? 167.731 105.974 114.726 1.00 42.15  ? 704 CYS D O   1 
ATOM   19492 C CB  . CYS D 1 704 ? 168.206 107.207 111.828 1.00 33.76  ? 704 CYS D CB  1 
ATOM   19493 S SG  . CYS D 1 704 ? 168.538 108.519 110.630 1.00 52.07  ? 704 CYS D SG  1 
ATOM   19494 N N   . PHE D 1 705 ? 166.328 107.695 114.498 1.00 23.79  ? 705 PHE D N   1 
ATOM   19495 C CA  . PHE D 1 705 ? 165.325 107.230 115.438 1.00 22.82  ? 705 PHE D CA  1 
ATOM   19496 C C   . PHE D 1 705 ? 164.014 106.918 114.728 1.00 23.91  ? 705 PHE D C   1 
ATOM   19497 O O   . PHE D 1 705 ? 163.446 107.779 114.058 1.00 26.27  ? 705 PHE D O   1 
ATOM   19498 C CB  . PHE D 1 705 ? 165.205 108.312 116.496 1.00 26.86  ? 705 PHE D CB  1 
ATOM   19499 C CG  . PHE D 1 705 ? 164.243 108.042 117.624 1.00 27.04  ? 705 PHE D CG  1 
ATOM   19500 C CD1 . PHE D 1 705 ? 164.621 107.204 118.683 1.00 27.43  ? 705 PHE D CD1 1 
ATOM   19501 C CD2 . PHE D 1 705 ? 163.003 108.693 117.645 1.00 25.57  ? 705 PHE D CD2 1 
ATOM   19502 C CE1 . PHE D 1 705 ? 163.745 107.001 119.761 1.00 27.12  ? 705 PHE D CE1 1 
ATOM   19503 C CE2 . PHE D 1 705 ? 162.132 108.490 118.719 1.00 28.26  ? 705 PHE D CE2 1 
ATOM   19504 C CZ  . PHE D 1 705 ? 162.497 107.639 119.772 1.00 24.70  ? 705 PHE D CZ  1 
ATOM   19505 N N   . ARG D 1 706 ? 163.550 105.675 114.852 1.00 30.98  ? 706 ARG D N   1 
ATOM   19506 C CA  . ARG D 1 706 ? 162.327 105.177 114.230 1.00 25.36  ? 706 ARG D CA  1 
ATOM   19507 C C   . ARG D 1 706 ? 161.089 105.634 114.988 1.00 23.96  ? 706 ARG D C   1 
ATOM   19508 O O   . ARG D 1 706 ? 160.918 105.316 116.161 1.00 32.09  ? 706 ARG D O   1 
ATOM   19509 C CB  . ARG D 1 706 ? 162.431 103.652 114.119 1.00 30.40  ? 706 ARG D CB  1 
ATOM   19510 C CG  . ARG D 1 706 ? 161.266 103.036 113.346 1.00 31.63  ? 706 ARG D CG  1 
ATOM   19511 C CD  . ARG D 1 706 ? 161.463 101.534 113.149 1.00 34.00  ? 706 ARG D CD  1 
ATOM   19512 N NE  . ARG D 1 706 ? 162.518 101.254 112.165 1.00 35.80  ? 706 ARG D NE  1 
ATOM   19513 C CZ  . ARG D 1 706 ? 163.716 100.744 112.346 1.00 39.58  ? 706 ARG D CZ  1 
ATOM   19514 N NH1 . ARG D 1 706 ? 164.512 100.584 111.338 1.00 32.26  ? 706 ARG D NH1 1 
ATOM   19515 N NH2 . ARG D 1 706 ? 164.149 100.393 113.518 1.00 39.62  ? 706 ARG D NH2 1 
ATOM   19516 N N   . VAL D 1 707 ? 160.202 106.333 114.299 1.00 29.09  ? 707 VAL D N   1 
ATOM   19517 C CA  . VAL D 1 707 ? 158.896 106.775 114.792 1.00 27.48  ? 707 VAL D CA  1 
ATOM   19518 C C   . VAL D 1 707 ? 157.812 106.177 113.900 1.00 32.06  ? 707 VAL D C   1 
ATOM   19519 O O   . VAL D 1 707 ? 157.919 106.196 112.678 1.00 36.12  ? 707 VAL D O   1 
ATOM   19520 C CB  . VAL D 1 707 ? 158.807 108.309 114.846 1.00 32.19  ? 707 VAL D CB  1 
ATOM   19521 C CG1 . VAL D 1 707 ? 157.472 108.789 115.416 1.00 25.98  ? 707 VAL D CG1 1 
ATOM   19522 C CG2 . VAL D 1 707 ? 159.914 108.937 115.696 1.00 32.26  ? 707 VAL D CG2 1 
ATOM   19523 N N   . GLU D 1 708 ? 156.768 105.632 114.508 1.00 40.98  ? 708 GLU D N   1 
ATOM   19524 C CA  . GLU D 1 708 ? 155.619 105.076 113.805 1.00 31.70  ? 708 GLU D CA  1 
ATOM   19525 C C   . GLU D 1 708 ? 154.426 105.992 114.073 1.00 36.03  ? 708 GLU D C   1 
ATOM   19526 O O   . GLU D 1 708 ? 153.980 106.131 115.209 1.00 45.02  ? 708 GLU D O   1 
ATOM   19527 C CB  . GLU D 1 708 ? 155.345 103.639 114.284 1.00 35.70  ? 708 GLU D CB  1 
ATOM   19528 C CG  . GLU D 1 708 ? 156.585 102.731 114.299 1.00 37.57  ? 708 GLU D CG  1 
ATOM   19529 C CD  . GLU D 1 708 ? 156.310 101.333 114.871 1.00 46.39  ? 708 GLU D CD  1 
ATOM   19530 O OE1 . GLU D 1 708 ? 155.402 101.180 115.719 1.00 48.97  ? 708 GLU D OE1 1 
ATOM   19531 O OE2 . GLU D 1 708 ? 157.047 100.385 114.516 1.00 47.67  ? 708 GLU D OE2 1 
ATOM   19532 N N   . GLU D 1 709 ? 153.907 106.640 113.040 1.00 41.77  ? 709 GLU D N   1 
ATOM   19533 C CA  . GLU D 1 709 ? 152.722 107.490 113.117 1.00 40.39  ? 709 GLU D CA  1 
ATOM   19534 C C   . GLU D 1 709 ? 151.544 106.711 112.543 1.00 43.47  ? 709 GLU D C   1 
ATOM   19535 O O   . GLU D 1 709 ? 151.619 106.212 111.423 1.00 42.80  ? 709 GLU D O   1 
ATOM   19536 C CB  . GLU D 1 709 ? 152.954 108.809 112.355 1.00 41.51  ? 709 GLU D CB  1 
ATOM   19537 C CG  . GLU D 1 709 ? 151.697 109.698 112.332 1.00 45.40  ? 709 GLU D CG  1 
ATOM   19538 C CD  . GLU D 1 709 ? 151.821 110.991 111.506 1.00 51.18  ? 709 GLU D CD  1 
ATOM   19539 O OE1 . GLU D 1 709 ? 152.774 111.145 110.710 1.00 51.45  ? 709 GLU D OE1 1 
ATOM   19540 O OE2 . GLU D 1 709 ? 150.914 111.850 111.620 1.00 48.74  ? 709 GLU D OE2 1 
ATOM   19541 N N   . VAL D 1 710 ? 150.434 106.646 113.278 1.00 43.86  ? 710 VAL D N   1 
ATOM   19542 C CA  . VAL D 1 710 ? 149.142 106.224 112.739 1.00 40.85  ? 710 VAL D CA  1 
ATOM   19543 C C   . VAL D 1 710 ? 148.239 107.447 112.681 1.00 37.06  ? 710 VAL D C   1 
ATOM   19544 O O   . VAL D 1 710 ? 148.025 108.105 113.696 1.00 42.17  ? 710 VAL D O   1 
ATOM   19545 C CB  . VAL D 1 710 ? 148.502 105.094 113.558 1.00 39.94  ? 710 VAL D CB  1 
ATOM   19546 C CG1 . VAL D 1 710 ? 147.276 104.548 112.824 1.00 39.21  ? 710 VAL D CG1 1 
ATOM   19547 C CG2 . VAL D 1 710 ? 149.483 103.949 113.821 1.00 39.17  ? 710 VAL D CG2 1 
ATOM   19548 N N   . ASN D 1 711 ? 147.718 107.782 111.505 1.00 39.11  ? 711 ASN D N   1 
ATOM   19549 C CA  . ASN D 1 711 ? 146.928 108.994 111.301 1.00 37.09  ? 711 ASN D CA  1 
ATOM   19550 C C   . ASN D 1 711 ? 145.860 108.770 110.222 1.00 40.16  ? 711 ASN D C   1 
ATOM   19551 O O   . ASN D 1 711 ? 146.053 109.082 109.051 1.00 47.70  ? 711 ASN D O   1 
ATOM   19552 C CB  . ASN D 1 711 ? 147.898 110.147 111.000 1.00 40.55  ? 711 ASN D CB  1 
ATOM   19553 C CG  . ASN D 1 711 ? 147.268 111.519 111.131 1.00 43.15  ? 711 ASN D CG  1 
ATOM   19554 O OD1 . ASN D 1 711 ? 146.062 111.697 111.060 1.00 43.03  ? 711 ASN D OD1 1 
ATOM   19555 N ND2 . ASN D 1 711 ? 148.080 112.525 111.340 1.00 45.57  ? 711 ASN D ND2 1 
ATOM   19556 N N   . TRP D 1 712 ? 144.722 108.210 110.627 1.00 37.99  ? 712 TRP D N   1 
ATOM   19557 C CA  . TRP D 1 712 ? 143.574 107.938 109.761 1.00 37.64  ? 712 TRP D CA  1 
ATOM   19558 C C   . TRP D 1 712 ? 142.986 109.200 109.139 1.00 39.17  ? 712 TRP D C   1 
ATOM   19559 O O   . TRP D 1 712 ? 142.703 109.215 107.947 1.00 42.13  ? 712 TRP D O   1 
ATOM   19560 C CB  . TRP D 1 712 ? 142.492 107.231 110.581 1.00 41.29  ? 712 TRP D CB  1 
ATOM   19561 C CG  . TRP D 1 712 ? 142.779 105.819 110.960 1.00 39.45  ? 712 TRP D CG  1 
ATOM   19562 C CD1 . TRP D 1 712 ? 143.486 105.408 112.032 1.00 41.04  ? 712 TRP D CD1 1 
ATOM   19563 C CD2 . TRP D 1 712 ? 142.330 104.604 110.285 1.00 38.26  ? 712 TRP D CD2 1 
ATOM   19564 N NE1 . TRP D 1 712 ? 143.519 104.030 112.065 1.00 42.60  ? 712 TRP D NE1 1 
ATOM   19565 C CE2 . TRP D 1 712 ? 142.794 103.485 111.034 1.00 41.39  ? 712 TRP D CE2 1 
ATOM   19566 C CE3 . TRP D 1 712 ? 141.533 104.343 109.155 1.00 34.27  ? 712 TRP D CE3 1 
ATOM   19567 C CZ2 . TRP D 1 712 ? 142.477 102.169 110.678 1.00 40.61  ? 712 TRP D CZ2 1 
ATOM   19568 C CZ3 . TRP D 1 712 ? 141.207 103.023 108.791 1.00 34.62  ? 712 TRP D CZ3 1 
ATOM   19569 C CH2 . TRP D 1 712 ? 141.673 101.942 109.556 1.00 39.78  ? 712 TRP D CH2 1 
ATOM   19570 N N   . ALA D 1 713 ? 142.842 110.269 109.917 1.00 44.85  ? 713 ALA D N   1 
ATOM   19571 C CA  . ALA D 1 713 ? 142.271 111.524 109.446 1.00 43.61  ? 713 ALA D CA  1 
ATOM   19572 C C   . ALA D 1 713 ? 143.114 112.170 108.335 1.00 45.88  ? 713 ALA D C   1 
ATOM   19573 O O   . ALA D 1 713 ? 142.565 112.613 107.332 1.00 49.51  ? 713 ALA D O   1 
ATOM   19574 C CB  . ALA D 1 713 ? 142.094 112.453 110.650 1.00 43.41  ? 713 ALA D CB  1 
ATOM   19575 N N   . ALA D 1 714 ? 144.444 112.186 108.465 1.00 44.29  ? 714 ALA D N   1 
ATOM   19576 C CA  . ALA D 1 714 ? 145.323 112.665 107.407 1.00 40.89  ? 714 ALA D CA  1 
ATOM   19577 C C   . ALA D 1 714 ? 145.346 111.728 106.192 1.00 44.56  ? 714 ALA D C   1 
ATOM   19578 O O   . ALA D 1 714 ? 145.380 112.195 105.057 1.00 48.15  ? 714 ALA D O   1 
ATOM   19579 C CB  . ALA D 1 714 ? 146.729 112.858 107.974 1.00 42.47  ? 714 ALA D CB  1 
ATOM   19580 N N   . TRP D 1 715 ? 145.306 110.413 106.406 1.00 41.71  ? 715 TRP D N   1 
ATOM   19581 C CA  . TRP D 1 715 ? 145.343 109.425 105.330 1.00 42.93  ? 715 TRP D CA  1 
ATOM   19582 C C   . TRP D 1 715 ? 144.079 109.423 104.472 1.00 42.69  ? 715 TRP D C   1 
ATOM   19583 O O   . TRP D 1 715 ? 144.180 109.508 103.252 1.00 46.29  ? 715 TRP D O   1 
ATOM   19584 C CB  . TRP D 1 715 ? 145.624 108.049 105.926 1.00 38.51  ? 715 TRP D CB  1 
ATOM   19585 C CG  . TRP D 1 715 ? 145.481 106.905 104.979 1.00 38.24  ? 715 TRP D CG  1 
ATOM   19586 C CD1 . TRP D 1 715 ? 146.270 106.660 103.915 1.00 36.87  ? 715 TRP D CD1 1 
ATOM   19587 C CD2 . TRP D 1 715 ? 144.477 105.851 104.983 1.00 41.69  ? 715 TRP D CD2 1 
ATOM   19588 N NE1 . TRP D 1 715 ? 145.842 105.514 103.277 1.00 40.10  ? 715 TRP D NE1 1 
ATOM   19589 C CE2 . TRP D 1 715 ? 144.752 104.959 103.910 1.00 39.79  ? 715 TRP D CE2 1 
ATOM   19590 C CE3 . TRP D 1 715 ? 143.376 105.543 105.807 1.00 34.42  ? 715 TRP D CE3 1 
ATOM   19591 C CZ2 . TRP D 1 715 ? 143.999 103.804 103.675 1.00 38.79  ? 715 TRP D CZ2 1 
ATOM   19592 C CZ3 . TRP D 1 715 ? 142.610 104.392 105.581 1.00 38.19  ? 715 TRP D CZ3 1 
ATOM   19593 C CH2 . TRP D 1 715 ? 142.922 103.517 104.529 1.00 38.69  ? 715 TRP D CH2 1 
ATOM   19594 N N   . GLU D 1 716 ? 142.886 109.407 105.067 1.00 49.29  ? 716 GLU D N   1 
ATOM   19595 C CA  . GLU D 1 716 ? 141.626 109.361 104.315 1.00 51.15  ? 716 GLU D CA  1 
ATOM   19596 C C   . GLU D 1 716 ? 141.429 110.560 103.378 1.00 55.42  ? 716 GLU D C   1 
ATOM   19597 O O   . GLU D 1 716 ? 140.899 110.411 102.280 1.00 58.35  ? 716 GLU D O   1 
ATOM   19598 C CB  . GLU D 1 716 ? 140.440 109.254 105.276 1.00 50.87  ? 716 GLU D CB  1 
ATOM   19599 C CG  . GLU D 1 716 ? 140.317 107.842 105.857 1.00 56.54  ? 716 GLU D CG  1 
ATOM   19600 C CD  . GLU D 1 716 ? 138.948 107.613 106.511 1.00 57.04  ? 716 GLU D CD  1 
ATOM   19601 O OE1 . GLU D 1 716 ? 138.455 108.520 107.213 1.00 55.54  ? 716 GLU D OE1 1 
ATOM   19602 O OE2 . GLU D 1 716 ? 138.358 106.533 106.284 1.00 56.04  ? 716 GLU D OE2 1 
ATOM   19603 N N   . LYS D 1 717 ? 141.942 111.738 103.753 1.00 52.19  ? 717 LYS D N   1 
ATOM   19604 C CA  . LYS D 1 717 ? 141.938 112.942 102.908 1.00 51.99  ? 717 LYS D CA  1 
ATOM   19605 C C   . LYS D 1 717 ? 142.774 112.801 101.632 1.00 54.51  ? 717 LYS D C   1 
ATOM   19606 O O   . LYS D 1 717 ? 142.540 113.544 100.682 1.00 59.27  ? 717 LYS D O   1 
ATOM   19607 C CB  . LYS D 1 717 ? 142.409 114.142 103.740 1.00 52.36  ? 717 LYS D CB  1 
ATOM   19608 C CG  . LYS D 1 717 ? 141.374 114.509 104.814 1.00 55.04  ? 717 LYS D CG  1 
ATOM   19609 C CD  . LYS D 1 717 ? 141.899 115.601 105.750 1.00 56.54  ? 717 LYS D CD  1 
ATOM   19610 C CE  . LYS D 1 717 ? 140.900 115.811 106.891 1.00 56.49  ? 717 LYS D CE  1 
ATOM   19611 N NZ  . LYS D 1 717 ? 141.343 116.873 107.822 1.00 55.74  ? 717 LYS D NZ  1 
ATOM   19612 N N   . THR D 1 718 ? 143.707 111.852 101.569 1.00 49.56  ? 718 THR D N   1 
ATOM   19613 C CA  . THR D 1 718 ? 144.522 111.573 100.369 1.00 50.56  ? 718 THR D CA  1 
ATOM   19614 C C   . THR D 1 718 ? 143.841 110.648 99.355  1.00 52.71  ? 718 THR D C   1 
ATOM   19615 O O   . THR D 1 718 ? 144.295 110.557 98.213  1.00 54.89  ? 718 THR D O   1 
ATOM   19616 C CB  . THR D 1 718 ? 145.902 110.986 100.711 1.00 54.54  ? 718 THR D CB  1 
ATOM   19617 O OG1 . THR D 1 718 ? 145.829 109.654 101.165 1.00 53.65  ? 718 THR D OG1 1 
ATOM   19618 C CG2 . THR D 1 718 ? 146.648 111.804 101.760 1.00 53.69  ? 718 THR D CG2 1 
ATOM   19619 N N   . LEU D 1 719 ? 142.773 109.945 99.733  1.00 49.98  ? 719 LEU D N   1 
ATOM   19620 C CA  . LEU D 1 719 ? 142.154 108.911 98.900  1.00 52.53  ? 719 LEU D CA  1 
ATOM   19621 C C   . LEU D 1 719 ? 141.319 109.528 97.772  1.00 55.35  ? 719 LEU D C   1 
ATOM   19622 O O   . LEU D 1 719 ? 141.204 108.955 96.686  1.00 54.07  ? 719 LEU D O   1 
ATOM   19623 C CB  . LEU D 1 719 ? 141.321 107.952 99.777  1.00 54.46  ? 719 LEU D CB  1 
ATOM   19624 C CG  . LEU D 1 719 ? 142.080 107.327 100.964 1.00 52.49  ? 719 LEU D CG  1 
ATOM   19625 C CD1 . LEU D 1 719 ? 141.165 106.359 101.710 1.00 50.33  ? 719 LEU D CD1 1 
ATOM   19626 C CD2 . LEU D 1 719 ? 143.340 106.585 100.540 1.00 48.63  ? 719 LEU D CD2 1 
HETATM 19627 O O1  . PEX E 2 .   ? 114.262 100.402 142.372 1.00 30.36  ? 801 PEX A O1  1 
HETATM 19628 O O2  . PEX E 2 .   ? 114.007 98.172  143.304 1.00 40.41  ? 801 PEX A O2  1 
HETATM 19629 P P1  . PEX E 2 .   ? 114.477 99.548  143.558 1.00 47.47  ? 801 PEX A P1  1 
HETATM 19630 O O3  . PEX E 2 .   ? 113.800 100.183 144.875 1.00 42.01  ? 801 PEX A O3  1 
HETATM 19631 C C1  . PEX E 2 .   ? 113.898 99.523  146.163 1.00 33.07  ? 801 PEX A C1  1 
HETATM 19632 C C2  . PEX E 2 .   ? 112.503 99.055  146.636 1.00 24.62  ? 801 PEX A C2  1 
HETATM 19633 C C3  . PEX E 2 .   ? 111.758 98.262  145.559 1.00 34.11  ? 801 PEX A C3  1 
HETATM 19634 O O4  . PEX E 2 .   ? 110.451 97.996  146.081 1.00 43.43  ? 801 PEX A O4  1 
HETATM 19635 C C4  . PEX E 2 .   ? 109.938 96.760  145.971 1.00 36.76  ? 801 PEX A C4  1 
HETATM 19636 O O5  . PEX E 2 .   ? 110.531 95.819  145.483 1.00 40.18  ? 801 PEX A O5  1 
HETATM 19637 C C5  . PEX E 2 .   ? 108.595 96.671  146.672 1.00 38.99  ? 801 PEX A C5  1 
HETATM 19638 C C6  . PEX E 2 .   ? 107.962 95.264  146.702 1.00 38.74  ? 801 PEX A C6  1 
HETATM 19639 C C7  . PEX E 2 .   ? 108.483 94.412  147.880 1.00 38.70  ? 801 PEX A C7  1 
HETATM 19640 C C8  . PEX E 2 .   ? 108.024 92.948  147.753 1.00 42.02  ? 801 PEX A C8  1 
HETATM 19641 C C9  . PEX E 2 .   ? 108.602 92.038  148.856 1.00 42.63  ? 801 PEX A C9  1 
HETATM 19642 C C10 . PEX E 2 .   ? 108.564 90.548  148.447 1.00 38.78  ? 801 PEX A C10 1 
HETATM 19643 C C11 . PEX E 2 .   ? 109.493 89.659  149.303 1.00 39.93  ? 801 PEX A C11 1 
HETATM 19644 C C12 . PEX E 2 .   ? 109.852 88.346  148.589 1.00 36.28  ? 801 PEX A C12 1 
HETATM 19645 C C13 . PEX E 2 .   ? 110.882 87.520  149.347 1.00 37.26  ? 801 PEX A C13 1 
HETATM 19646 O O6  . PEX E 2 .   ? 112.629 98.166  147.780 1.00 39.90  ? 801 PEX A O6  1 
HETATM 19647 C C14 . PEX E 2 .   ? 112.653 98.677  149.039 1.00 34.98  ? 801 PEX A C14 1 
HETATM 19648 O O7  . PEX E 2 .   ? 112.611 99.854  149.279 1.00 41.26  ? 801 PEX A O7  1 
HETATM 19649 C C15 . PEX E 2 .   ? 112.577 97.625  150.134 1.00 31.79  ? 801 PEX A C15 1 
HETATM 19650 C C16 . PEX E 2 .   ? 111.137 97.482  150.680 1.00 36.28  ? 801 PEX A C16 1 
HETATM 19651 C C17 . PEX E 2 .   ? 111.080 96.853  152.089 1.00 33.71  ? 801 PEX A C17 1 
HETATM 19652 C C18 . PEX E 2 .   ? 111.274 95.319  152.124 1.00 39.51  ? 801 PEX A C18 1 
HETATM 19653 C C19 . PEX E 2 .   ? 110.055 94.516  151.603 1.00 41.91  ? 801 PEX A C19 1 
HETATM 19654 C C20 . PEX E 2 .   ? 109.852 93.169  152.345 1.00 41.59  ? 801 PEX A C20 1 
HETATM 19655 C C21 . PEX E 2 .   ? 111.047 92.201  152.198 1.00 41.56  ? 801 PEX A C21 1 
HETATM 19656 C C22 . PEX E 2 .   ? 110.782 90.811  152.817 1.00 41.75  ? 801 PEX A C22 1 
HETATM 19657 C C23 . PEX E 2 .   ? 111.983 89.857  152.639 1.00 37.24  ? 801 PEX A C23 1 
HETATM 19658 O O8  . PEX E 2 .   ? 116.013 99.563  144.040 1.00 42.43  ? 801 PEX A O8  1 
HETATM 19659 C C24 . PEX E 2 .   ? 116.880 100.700 143.850 1.00 30.99  ? 801 PEX A C24 1 
HETATM 19660 C C25 . PEX E 2 .   ? 117.684 100.524 142.541 1.00 34.75  ? 801 PEX A C25 1 
HETATM 19661 N N1  . PEX E 2 .   ? 118.553 101.675 142.284 1.00 32.57  ? 801 PEX A N1  1 
HETATM 19662 C C13 . RTO F 3 .   ? 154.884 99.667  101.891 1.00 51.90  ? 802 RTO A C13 1 
HETATM 19663 C C15 . RTO F 3 .   ? 157.261 99.228  102.016 1.00 51.76  ? 802 RTO A C15 1 
HETATM 19664 C C17 . RTO F 3 .   ? 156.494 101.463 101.083 1.00 55.66  ? 802 RTO A C17 1 
HETATM 19665 C C01 . RTO F 3 .   ? 151.801 96.174  106.576 1.00 51.19  ? 802 RTO A C01 1 
HETATM 19666 C C02 . RTO F 3 .   ? 153.270 95.787  106.431 1.00 50.32  ? 802 RTO A C02 1 
HETATM 19667 C C03 . RTO F 3 .   ? 154.052 96.741  105.517 1.00 52.91  ? 802 RTO A C03 1 
HETATM 19668 C C05 . RTO F 3 .   ? 156.529 96.441  105.656 1.00 51.57  ? 802 RTO A C05 1 
HETATM 19669 C C06 . RTO F 3 .   ? 156.555 96.056  107.146 1.00 51.26  ? 802 RTO A C06 1 
HETATM 19670 C C07 . RTO F 3 .   ? 157.988 96.019  107.709 1.00 54.11  ? 802 RTO A C07 1 
HETATM 19671 C C11 . RTO F 3 .   ? 155.671 97.536  102.744 1.00 54.19  ? 802 RTO A C11 1 
HETATM 19672 C C12 . RTO F 3 .   ? 154.618 98.398  102.416 1.00 50.73  ? 802 RTO A C12 1 
HETATM 19673 C C14 . RTO F 3 .   ? 156.208 100.103 101.679 1.00 54.11  ? 802 RTO A C14 1 
HETATM 19674 C C16 . RTO F 3 .   ? 156.997 97.959  102.548 1.00 53.79  ? 802 RTO A C16 1 
HETATM 19675 N N04 . RTO F 3 .   ? 155.261 96.069  104.998 1.00 56.81  ? 802 RTO A N04 1 
HETATM 19676 O O09 . RTO F 3 .   ? 153.981 95.461  102.918 1.00 56.57  ? 802 RTO A O09 1 
HETATM 19677 O O10 . RTO F 3 .   ? 156.481 95.016  103.073 1.00 57.93  ? 802 RTO A O10 1 
HETATM 19678 O O18 . RTO F 3 .   ? 157.633 101.893 101.138 1.00 55.76  ? 802 RTO A O18 1 
HETATM 19679 O O19 . RTO F 3 .   ? 155.584 102.051 100.524 1.00 56.11  ? 802 RTO A O19 1 
HETATM 19680 S S08 . RTO F 3 .   ? 155.324 95.878  103.328 1.00 64.69  ? 802 RTO A S08 1 
HETATM 19681 C C13 . RTO G 3 .   ? 99.667  110.716 101.891 1.00 51.90  ? 803 RTO A C13 1 
HETATM 19682 C C15 . RTO G 3 .   ? 99.228  108.339 102.016 1.00 51.76  ? 803 RTO A C15 1 
HETATM 19683 C C17 . RTO G 3 .   ? 101.463 109.106 101.083 1.00 55.66  ? 803 RTO A C17 1 
HETATM 19684 C C01 . RTO G 3 .   ? 96.174  113.799 106.576 1.00 51.19  ? 803 RTO A C01 1 
HETATM 19685 C C02 . RTO G 3 .   ? 95.787  112.330 106.431 1.00 50.32  ? 803 RTO A C02 1 
HETATM 19686 C C03 . RTO G 3 .   ? 96.741  111.548 105.517 1.00 52.91  ? 803 RTO A C03 1 
HETATM 19687 C C05 . RTO G 3 .   ? 96.441  109.071 105.656 1.00 51.57  ? 803 RTO A C05 1 
HETATM 19688 C C06 . RTO G 3 .   ? 96.056  109.045 107.146 1.00 51.26  ? 803 RTO A C06 1 
HETATM 19689 C C07 . RTO G 3 .   ? 96.019  107.612 107.709 1.00 54.11  ? 803 RTO A C07 1 
HETATM 19690 C C11 . RTO G 3 .   ? 97.536  109.929 102.744 1.00 54.19  ? 803 RTO A C11 1 
HETATM 19691 C C12 . RTO G 3 .   ? 98.398  110.982 102.416 1.00 50.73  ? 803 RTO A C12 1 
HETATM 19692 C C14 . RTO G 3 .   ? 100.103 109.392 101.679 1.00 54.11  ? 803 RTO A C14 1 
HETATM 19693 C C16 . RTO G 3 .   ? 97.959  108.603 102.548 1.00 53.79  ? 803 RTO A C16 1 
HETATM 19694 N N04 . RTO G 3 .   ? 96.069  110.339 104.998 1.00 56.81  ? 803 RTO A N04 1 
HETATM 19695 O O09 . RTO G 3 .   ? 95.461  111.619 102.918 1.00 56.57  ? 803 RTO A O09 1 
HETATM 19696 O O10 . RTO G 3 .   ? 95.016  109.119 103.073 1.00 57.93  ? 803 RTO A O10 1 
HETATM 19697 O O18 . RTO G 3 .   ? 101.893 107.967 101.138 1.00 55.76  ? 803 RTO A O18 1 
HETATM 19698 O O19 . RTO G 3 .   ? 102.051 110.016 100.524 1.00 56.11  ? 803 RTO A O19 1 
HETATM 19699 S S08 . RTO G 3 .   ? 95.878  110.276 103.328 1.00 64.69  ? 803 RTO A S08 1 
HETATM 19700 O O1  . PEX H 2 .   ? 100.402 151.338 142.372 1.00 30.36  ? 801 PEX B O1  1 
HETATM 19701 O O2  . PEX H 2 .   ? 98.172  151.593 143.304 1.00 40.41  ? 801 PEX B O2  1 
HETATM 19702 P P1  . PEX H 2 .   ? 99.548  151.123 143.558 1.00 47.47  ? 801 PEX B P1  1 
HETATM 19703 O O3  . PEX H 2 .   ? 100.183 151.800 144.875 1.00 42.01  ? 801 PEX B O3  1 
HETATM 19704 C C1  . PEX H 2 .   ? 99.523  151.702 146.163 1.00 33.07  ? 801 PEX B C1  1 
HETATM 19705 C C2  . PEX H 2 .   ? 99.055  153.097 146.636 1.00 24.62  ? 801 PEX B C2  1 
HETATM 19706 C C3  . PEX H 2 .   ? 98.262  153.842 145.559 1.00 34.11  ? 801 PEX B C3  1 
HETATM 19707 O O4  . PEX H 2 .   ? 97.996  155.149 146.081 1.00 43.43  ? 801 PEX B O4  1 
HETATM 19708 C C4  . PEX H 2 .   ? 96.760  155.662 145.971 1.00 36.76  ? 801 PEX B C4  1 
HETATM 19709 O O5  . PEX H 2 .   ? 95.819  155.069 145.483 1.00 40.18  ? 801 PEX B O5  1 
HETATM 19710 C C5  . PEX H 2 .   ? 96.671  157.005 146.672 1.00 38.99  ? 801 PEX B C5  1 
HETATM 19711 C C6  . PEX H 2 .   ? 95.264  157.638 146.702 1.00 38.74  ? 801 PEX B C6  1 
HETATM 19712 C C7  . PEX H 2 .   ? 94.412  157.117 147.880 1.00 38.70  ? 801 PEX B C7  1 
HETATM 19713 C C8  . PEX H 2 .   ? 92.948  157.576 147.753 1.00 42.02  ? 801 PEX B C8  1 
HETATM 19714 C C9  . PEX H 2 .   ? 92.038  156.998 148.856 1.00 42.63  ? 801 PEX B C9  1 
HETATM 19715 C C10 . PEX H 2 .   ? 90.548  157.036 148.447 1.00 38.78  ? 801 PEX B C10 1 
HETATM 19716 C C11 . PEX H 2 .   ? 89.659  156.107 149.303 1.00 39.93  ? 801 PEX B C11 1 
HETATM 19717 C C12 . PEX H 2 .   ? 88.346  155.748 148.589 1.00 36.28  ? 801 PEX B C12 1 
HETATM 19718 C C13 . PEX H 2 .   ? 87.520  154.718 149.347 1.00 37.26  ? 801 PEX B C13 1 
HETATM 19719 O O6  . PEX H 2 .   ? 98.166  152.971 147.780 1.00 39.90  ? 801 PEX B O6  1 
HETATM 19720 C C14 . PEX H 2 .   ? 98.677  152.947 149.039 1.00 34.98  ? 801 PEX B C14 1 
HETATM 19721 O O7  . PEX H 2 .   ? 99.854  152.989 149.279 1.00 41.26  ? 801 PEX B O7  1 
HETATM 19722 C C15 . PEX H 2 .   ? 97.625  153.023 150.134 1.00 31.79  ? 801 PEX B C15 1 
HETATM 19723 C C16 . PEX H 2 .   ? 97.482  154.463 150.680 1.00 36.28  ? 801 PEX B C16 1 
HETATM 19724 C C17 . PEX H 2 .   ? 96.853  154.520 152.089 1.00 33.71  ? 801 PEX B C17 1 
HETATM 19725 C C18 . PEX H 2 .   ? 95.319  154.326 152.124 1.00 39.51  ? 801 PEX B C18 1 
HETATM 19726 C C19 . PEX H 2 .   ? 94.516  155.545 151.603 1.00 41.91  ? 801 PEX B C19 1 
HETATM 19727 C C20 . PEX H 2 .   ? 93.169  155.748 152.345 1.00 41.59  ? 801 PEX B C20 1 
HETATM 19728 C C21 . PEX H 2 .   ? 92.201  154.553 152.198 1.00 41.56  ? 801 PEX B C21 1 
HETATM 19729 C C22 . PEX H 2 .   ? 90.811  154.818 152.817 1.00 41.75  ? 801 PEX B C22 1 
HETATM 19730 C C23 . PEX H 2 .   ? 89.857  153.617 152.639 1.00 37.24  ? 801 PEX B C23 1 
HETATM 19731 O O8  . PEX H 2 .   ? 99.563  149.587 144.040 1.00 42.43  ? 801 PEX B O8  1 
HETATM 19732 C C24 . PEX H 2 .   ? 100.700 148.720 143.850 1.00 30.99  ? 801 PEX B C24 1 
HETATM 19733 C C25 . PEX H 2 .   ? 100.524 147.916 142.541 1.00 34.75  ? 801 PEX B C25 1 
HETATM 19734 N N1  . PEX H 2 .   ? 101.675 147.047 142.284 1.00 32.57  ? 801 PEX B N1  1 
HETATM 19735 C C13 . RTO I 3 .   ? 110.716 165.933 101.891 1.00 51.90  ? 802 RTO B C13 1 
HETATM 19736 C C15 . RTO I 3 .   ? 108.339 166.372 102.016 1.00 51.76  ? 802 RTO B C15 1 
HETATM 19737 C C17 . RTO I 3 .   ? 109.106 164.137 101.083 1.00 55.66  ? 802 RTO B C17 1 
HETATM 19738 C C01 . RTO I 3 .   ? 113.799 169.426 106.576 1.00 51.19  ? 802 RTO B C01 1 
HETATM 19739 C C02 . RTO I 3 .   ? 112.330 169.813 106.431 1.00 50.32  ? 802 RTO B C02 1 
HETATM 19740 C C03 . RTO I 3 .   ? 111.548 168.859 105.517 1.00 52.91  ? 802 RTO B C03 1 
HETATM 19741 C C05 . RTO I 3 .   ? 109.071 169.159 105.656 1.00 51.57  ? 802 RTO B C05 1 
HETATM 19742 C C06 . RTO I 3 .   ? 109.045 169.544 107.146 1.00 51.26  ? 802 RTO B C06 1 
HETATM 19743 C C07 . RTO I 3 .   ? 107.612 169.581 107.709 1.00 54.11  ? 802 RTO B C07 1 
HETATM 19744 C C11 . RTO I 3 .   ? 109.929 168.064 102.744 1.00 54.19  ? 802 RTO B C11 1 
HETATM 19745 C C12 . RTO I 3 .   ? 110.982 167.202 102.416 1.00 50.73  ? 802 RTO B C12 1 
HETATM 19746 C C14 . RTO I 3 .   ? 109.392 165.497 101.679 1.00 54.11  ? 802 RTO B C14 1 
HETATM 19747 C C16 . RTO I 3 .   ? 108.603 167.641 102.548 1.00 53.79  ? 802 RTO B C16 1 
HETATM 19748 N N04 . RTO I 3 .   ? 110.339 169.531 104.998 1.00 56.81  ? 802 RTO B N04 1 
HETATM 19749 O O09 . RTO I 3 .   ? 111.619 170.139 102.918 1.00 56.57  ? 802 RTO B O09 1 
HETATM 19750 O O10 . RTO I 3 .   ? 109.119 170.584 103.073 1.00 57.93  ? 802 RTO B O10 1 
HETATM 19751 O O18 . RTO I 3 .   ? 107.967 163.707 101.138 1.00 55.76  ? 802 RTO B O18 1 
HETATM 19752 O O19 . RTO I 3 .   ? 110.016 163.549 100.524 1.00 56.11  ? 802 RTO B O19 1 
HETATM 19753 S S08 . RTO I 3 .   ? 110.276 169.722 103.328 1.00 64.69  ? 802 RTO B S08 1 
HETATM 19754 O O1  . PEX J 2 .   ? 151.338 165.198 142.372 1.00 30.36  ? 801 PEX C O1  1 
HETATM 19755 O O2  . PEX J 2 .   ? 151.593 167.428 143.304 1.00 40.41  ? 801 PEX C O2  1 
HETATM 19756 P P1  . PEX J 2 .   ? 151.123 166.052 143.558 1.00 47.47  ? 801 PEX C P1  1 
HETATM 19757 O O3  . PEX J 2 .   ? 151.800 165.417 144.875 1.00 42.01  ? 801 PEX C O3  1 
HETATM 19758 C C1  . PEX J 2 .   ? 151.702 166.077 146.163 1.00 33.07  ? 801 PEX C C1  1 
HETATM 19759 C C2  . PEX J 2 .   ? 153.097 166.545 146.636 1.00 24.62  ? 801 PEX C C2  1 
HETATM 19760 C C3  . PEX J 2 .   ? 153.842 167.338 145.559 1.00 34.11  ? 801 PEX C C3  1 
HETATM 19761 O O4  . PEX J 2 .   ? 155.149 167.604 146.081 1.00 43.43  ? 801 PEX C O4  1 
HETATM 19762 C C4  . PEX J 2 .   ? 155.662 168.840 145.971 1.00 36.76  ? 801 PEX C C4  1 
HETATM 19763 O O5  . PEX J 2 .   ? 155.069 169.781 145.483 1.00 40.18  ? 801 PEX C O5  1 
HETATM 19764 C C5  . PEX J 2 .   ? 157.005 168.929 146.672 1.00 38.99  ? 801 PEX C C5  1 
HETATM 19765 C C6  . PEX J 2 .   ? 157.638 170.336 146.702 1.00 38.74  ? 801 PEX C C6  1 
HETATM 19766 C C7  . PEX J 2 .   ? 157.117 171.188 147.880 1.00 38.70  ? 801 PEX C C7  1 
HETATM 19767 C C8  . PEX J 2 .   ? 157.576 172.652 147.753 1.00 42.02  ? 801 PEX C C8  1 
HETATM 19768 C C9  . PEX J 2 .   ? 156.998 173.562 148.856 1.00 42.63  ? 801 PEX C C9  1 
HETATM 19769 C C10 . PEX J 2 .   ? 157.036 175.052 148.447 1.00 38.78  ? 801 PEX C C10 1 
HETATM 19770 C C11 . PEX J 2 .   ? 156.107 175.941 149.303 1.00 39.93  ? 801 PEX C C11 1 
HETATM 19771 C C12 . PEX J 2 .   ? 155.748 177.254 148.589 1.00 36.28  ? 801 PEX C C12 1 
HETATM 19772 C C13 . PEX J 2 .   ? 154.718 178.080 149.347 1.00 37.26  ? 801 PEX C C13 1 
HETATM 19773 O O6  . PEX J 2 .   ? 152.971 167.434 147.780 1.00 39.90  ? 801 PEX C O6  1 
HETATM 19774 C C14 . PEX J 2 .   ? 152.947 166.923 149.039 1.00 34.98  ? 801 PEX C C14 1 
HETATM 19775 O O7  . PEX J 2 .   ? 152.989 165.746 149.279 1.00 41.26  ? 801 PEX C O7  1 
HETATM 19776 C C15 . PEX J 2 .   ? 153.023 167.975 150.134 1.00 31.79  ? 801 PEX C C15 1 
HETATM 19777 C C16 . PEX J 2 .   ? 154.463 168.118 150.680 1.00 36.28  ? 801 PEX C C16 1 
HETATM 19778 C C17 . PEX J 2 .   ? 154.520 168.747 152.089 1.00 33.71  ? 801 PEX C C17 1 
HETATM 19779 C C18 . PEX J 2 .   ? 154.326 170.281 152.124 1.00 39.51  ? 801 PEX C C18 1 
HETATM 19780 C C19 . PEX J 2 .   ? 155.545 171.084 151.603 1.00 41.91  ? 801 PEX C C19 1 
HETATM 19781 C C20 . PEX J 2 .   ? 155.748 172.431 152.345 1.00 41.59  ? 801 PEX C C20 1 
HETATM 19782 C C21 . PEX J 2 .   ? 154.553 173.399 152.198 1.00 41.56  ? 801 PEX C C21 1 
HETATM 19783 C C22 . PEX J 2 .   ? 154.818 174.789 152.817 1.00 41.75  ? 801 PEX C C22 1 
HETATM 19784 C C23 . PEX J 2 .   ? 153.617 175.743 152.639 1.00 37.24  ? 801 PEX C C23 1 
HETATM 19785 O O8  . PEX J 2 .   ? 149.587 166.037 144.040 1.00 42.43  ? 801 PEX C O8  1 
HETATM 19786 C C24 . PEX J 2 .   ? 148.720 164.900 143.850 1.00 30.99  ? 801 PEX C C24 1 
HETATM 19787 C C25 . PEX J 2 .   ? 147.916 165.076 142.541 1.00 34.75  ? 801 PEX C C25 1 
HETATM 19788 N N1  . PEX J 2 .   ? 147.047 163.925 142.284 1.00 32.57  ? 801 PEX C N1  1 
HETATM 19789 C C13 . RTO K 3 .   ? 165.933 154.884 101.891 1.00 51.90  ? 802 RTO C C13 1 
HETATM 19790 C C15 . RTO K 3 .   ? 166.372 157.261 102.016 1.00 51.76  ? 802 RTO C C15 1 
HETATM 19791 C C17 . RTO K 3 .   ? 164.137 156.494 101.083 1.00 55.66  ? 802 RTO C C17 1 
HETATM 19792 C C01 . RTO K 3 .   ? 169.426 151.801 106.576 1.00 51.19  ? 802 RTO C C01 1 
HETATM 19793 C C02 . RTO K 3 .   ? 169.813 153.270 106.431 1.00 50.32  ? 802 RTO C C02 1 
HETATM 19794 C C03 . RTO K 3 .   ? 168.859 154.052 105.517 1.00 52.91  ? 802 RTO C C03 1 
HETATM 19795 C C05 . RTO K 3 .   ? 169.159 156.529 105.656 1.00 51.57  ? 802 RTO C C05 1 
HETATM 19796 C C06 . RTO K 3 .   ? 169.544 156.555 107.146 1.00 51.26  ? 802 RTO C C06 1 
HETATM 19797 C C07 . RTO K 3 .   ? 169.581 157.988 107.709 1.00 54.11  ? 802 RTO C C07 1 
HETATM 19798 C C11 . RTO K 3 .   ? 168.064 155.671 102.744 1.00 54.19  ? 802 RTO C C11 1 
HETATM 19799 C C12 . RTO K 3 .   ? 167.202 154.618 102.416 1.00 50.73  ? 802 RTO C C12 1 
HETATM 19800 C C14 . RTO K 3 .   ? 165.497 156.208 101.679 1.00 54.11  ? 802 RTO C C14 1 
HETATM 19801 C C16 . RTO K 3 .   ? 167.641 156.997 102.548 1.00 53.79  ? 802 RTO C C16 1 
HETATM 19802 N N04 . RTO K 3 .   ? 169.531 155.261 104.998 1.00 56.81  ? 802 RTO C N04 1 
HETATM 19803 O O09 . RTO K 3 .   ? 170.139 153.981 102.918 1.00 56.57  ? 802 RTO C O09 1 
HETATM 19804 O O10 . RTO K 3 .   ? 170.584 156.481 103.073 1.00 57.93  ? 802 RTO C O10 1 
HETATM 19805 O O18 . RTO K 3 .   ? 163.707 157.633 101.138 1.00 55.76  ? 802 RTO C O18 1 
HETATM 19806 O O19 . RTO K 3 .   ? 163.549 155.584 100.524 1.00 56.11  ? 802 RTO C O19 1 
HETATM 19807 S S08 . RTO K 3 .   ? 169.722 155.324 103.328 1.00 64.69  ? 802 RTO C S08 1 
HETATM 19808 O O1  . PEX L 2 .   ? 165.198 114.262 142.372 1.00 30.36  ? 801 PEX D O1  1 
HETATM 19809 O O2  . PEX L 2 .   ? 167.428 114.007 143.304 1.00 40.41  ? 801 PEX D O2  1 
HETATM 19810 P P1  . PEX L 2 .   ? 166.052 114.477 143.558 1.00 47.47  ? 801 PEX D P1  1 
HETATM 19811 O O3  . PEX L 2 .   ? 165.417 113.800 144.875 1.00 42.01  ? 801 PEX D O3  1 
HETATM 19812 C C1  . PEX L 2 .   ? 166.077 113.898 146.163 1.00 33.07  ? 801 PEX D C1  1 
HETATM 19813 C C2  . PEX L 2 .   ? 166.545 112.503 146.636 1.00 24.62  ? 801 PEX D C2  1 
HETATM 19814 C C3  . PEX L 2 .   ? 167.338 111.758 145.559 1.00 34.11  ? 801 PEX D C3  1 
HETATM 19815 O O4  . PEX L 2 .   ? 167.604 110.451 146.081 1.00 43.43  ? 801 PEX D O4  1 
HETATM 19816 C C4  . PEX L 2 .   ? 168.840 109.938 145.971 1.00 36.76  ? 801 PEX D C4  1 
HETATM 19817 O O5  . PEX L 2 .   ? 169.781 110.531 145.483 1.00 40.18  ? 801 PEX D O5  1 
HETATM 19818 C C5  . PEX L 2 .   ? 168.929 108.595 146.672 1.00 38.99  ? 801 PEX D C5  1 
HETATM 19819 C C6  . PEX L 2 .   ? 170.336 107.962 146.702 1.00 38.74  ? 801 PEX D C6  1 
HETATM 19820 C C7  . PEX L 2 .   ? 171.188 108.483 147.880 1.00 38.70  ? 801 PEX D C7  1 
HETATM 19821 C C8  . PEX L 2 .   ? 172.652 108.024 147.753 1.00 42.02  ? 801 PEX D C8  1 
HETATM 19822 C C9  . PEX L 2 .   ? 173.562 108.602 148.856 1.00 42.63  ? 801 PEX D C9  1 
HETATM 19823 C C10 . PEX L 2 .   ? 175.052 108.564 148.447 1.00 38.78  ? 801 PEX D C10 1 
HETATM 19824 C C11 . PEX L 2 .   ? 175.941 109.493 149.303 1.00 39.93  ? 801 PEX D C11 1 
HETATM 19825 C C12 . PEX L 2 .   ? 177.254 109.852 148.589 1.00 36.28  ? 801 PEX D C12 1 
HETATM 19826 C C13 . PEX L 2 .   ? 178.080 110.882 149.347 1.00 37.26  ? 801 PEX D C13 1 
HETATM 19827 O O6  . PEX L 2 .   ? 167.434 112.629 147.780 1.00 39.90  ? 801 PEX D O6  1 
HETATM 19828 C C14 . PEX L 2 .   ? 166.923 112.653 149.039 1.00 34.98  ? 801 PEX D C14 1 
HETATM 19829 O O7  . PEX L 2 .   ? 165.746 112.611 149.279 1.00 41.26  ? 801 PEX D O7  1 
HETATM 19830 C C15 . PEX L 2 .   ? 167.975 112.577 150.134 1.00 31.79  ? 801 PEX D C15 1 
HETATM 19831 C C16 . PEX L 2 .   ? 168.118 111.137 150.680 1.00 36.28  ? 801 PEX D C16 1 
HETATM 19832 C C17 . PEX L 2 .   ? 168.747 111.080 152.089 1.00 33.71  ? 801 PEX D C17 1 
HETATM 19833 C C18 . PEX L 2 .   ? 170.281 111.274 152.124 1.00 39.51  ? 801 PEX D C18 1 
HETATM 19834 C C19 . PEX L 2 .   ? 171.084 110.055 151.603 1.00 41.91  ? 801 PEX D C19 1 
HETATM 19835 C C20 . PEX L 2 .   ? 172.431 109.852 152.345 1.00 41.59  ? 801 PEX D C20 1 
HETATM 19836 C C21 . PEX L 2 .   ? 173.399 111.047 152.198 1.00 41.56  ? 801 PEX D C21 1 
HETATM 19837 C C22 . PEX L 2 .   ? 174.789 110.782 152.817 1.00 41.75  ? 801 PEX D C22 1 
HETATM 19838 C C23 . PEX L 2 .   ? 175.743 111.983 152.639 1.00 37.24  ? 801 PEX D C23 1 
HETATM 19839 O O8  . PEX L 2 .   ? 166.037 116.013 144.040 1.00 42.43  ? 801 PEX D O8  1 
HETATM 19840 C C24 . PEX L 2 .   ? 164.900 116.880 143.850 1.00 30.99  ? 801 PEX D C24 1 
HETATM 19841 C C25 . PEX L 2 .   ? 165.076 117.684 142.541 1.00 34.75  ? 801 PEX D C25 1 
HETATM 19842 N N1  . PEX L 2 .   ? 163.925 118.553 142.284 1.00 32.57  ? 801 PEX D N1  1 
# 
