data_9B2O
# 
_entry.id   9B2O 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.398 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9B2O         pdb_00009b2o 10.2210/pdb9b2o/pdb 
WWPDB D_1000279116 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-06 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9B2O 
_pdbx_database_status.recvd_initial_deposition_date   2024-03-15 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_database_related.db_name        PDB 
_pdbx_database_related.details        . 
_pdbx_database_related.db_id          6n9i 
_pdbx_database_related.content_type   unspecified 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              mhelias@umn.edu 
_pdbx_contact_author.name_first         Mikael 
_pdbx_contact_author.name_last          Elias 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-0406-7539 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Corbella, M.'     1 ? 
'Bravo, J.A.'      2 ? 
'Demkiv, A.O.'     3 ? 
'Calixto, A.R.'    4 ? 
'Sompiyachoke, K.' 5 ? 
'Bergonzi, C.'     6 ? 
'Kamerlin, S.C.L.' 7 ? 
'Elias, M.'        8 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Jacs Au' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2691-3704 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            4 
_citation.language                  ? 
_citation.page_first                3519 
_citation.page_last                 3536 
_citation.title                     
'Catalytic Redundancies and Conformational Plasticity Drives Selectivity and Promiscuity in Quorum Quenching Lactonases.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/jacsau.4c00404 
_citation.pdbx_database_id_PubMed   39328773 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Corbella, M.'     1 0000-0001-9209-868X 
primary 'Bravo, J.'        2 ?                   
primary 'Demkiv, A.O.'     3 ?                   
primary 'Calixto, A.R.'    4 0000-0002-1123-0413 
primary 'Sompiyachoke, K.' 5 0000-0003-0627-8305 
primary 'Bergonzi, C.'     6 ?                   
primary 'Brownless, A.R.'  7 ?                   
primary 'Elias, M.H.'      8 0000-0003-0406-7539 
primary 'Kamerlin, S.C.L.' 9 0000-0002-3190-1173 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'GcL lactonase'         34378.914 3   ? ? ? ? 
2 non-polymer syn N-octanoyl-L-homoserine 245.315   3   ? ? ? ? 
3 non-polymer syn 'COBALT (II) ION'       58.933    3   ? ? ? ? 
4 non-polymer syn 'SULFATE ION'           96.063    5   ? ? ? ? 
5 non-polymer syn 'FE (III) ION'          55.845    3   ? ? ? ? 
6 water       nat water                   18.015    362 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;WSHPQFEKENLYFQSMANVIKARPKLYVMDNGRMRMDKNWMIAMHNPATIHNPNAQTEFVEFPIYTVLIDHPEGKILFDT
SCNPNSMGPQGRWAESTQQMFPWTATEECYLHNRLEQLKVRPEDIRYVVASHLHLDHAGCLEMFTNATIIVHEDEFNGAL
QCYARNQKEGAYIWADIDAWIKNNLQWRTVKRHEDNILLAEGVKVLNFGSGHAWGMLGLHVELPETGGIILASDAIYTAE
SYGPPIKPPGIIYDSLGYMNTVERIRRIAQETKSQVWFGHDAEQFKKFRKSTEGYYE
;
_entity_poly.pdbx_seq_one_letter_code_can   
;WSHPQFEKENLYFQSMANVIKARPKLYVMDNGRMRMDKNWMIAMHNPATIHNPNAQTEFVEFPIYTVLIDHPEGKILFDT
SCNPNSMGPQGRWAESTQQMFPWTATEECYLHNRLEQLKVRPEDIRYVVASHLHLDHAGCLEMFTNATIIVHEDEFNGAL
QCYARNQKEGAYIWADIDAWIKNNLQWRTVKRHEDNILLAEGVKVLNFGSGHAWGMLGLHVELPETGGIILASDAIYTAE
SYGPPIKPPGIIYDSLGYMNTVERIRRIAQETKSQVWFGHDAEQFKKFRKSTEGYYE
;
_entity_poly.pdbx_strand_id                 X,F,L 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 N-octanoyl-L-homoserine A1AI3 
3 'COBALT (II) ION'       CO    
4 'SULFATE ION'           SO4   
5 'FE (III) ION'          FE    
6 water                   HOH   
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   TRP n 
1 2   SER n 
1 3   HIS n 
1 4   PRO n 
1 5   GLN n 
1 6   PHE n 
1 7   GLU n 
1 8   LYS n 
1 9   GLU n 
1 10  ASN n 
1 11  LEU n 
1 12  TYR n 
1 13  PHE n 
1 14  GLN n 
1 15  SER n 
1 16  MET n 
1 17  ALA n 
1 18  ASN n 
1 19  VAL n 
1 20  ILE n 
1 21  LYS n 
1 22  ALA n 
1 23  ARG n 
1 24  PRO n 
1 25  LYS n 
1 26  LEU n 
1 27  TYR n 
1 28  VAL n 
1 29  MET n 
1 30  ASP n 
1 31  ASN n 
1 32  GLY n 
1 33  ARG n 
1 34  MET n 
1 35  ARG n 
1 36  MET n 
1 37  ASP n 
1 38  LYS n 
1 39  ASN n 
1 40  TRP n 
1 41  MET n 
1 42  ILE n 
1 43  ALA n 
1 44  MET n 
1 45  HIS n 
1 46  ASN n 
1 47  PRO n 
1 48  ALA n 
1 49  THR n 
1 50  ILE n 
1 51  HIS n 
1 52  ASN n 
1 53  PRO n 
1 54  ASN n 
1 55  ALA n 
1 56  GLN n 
1 57  THR n 
1 58  GLU n 
1 59  PHE n 
1 60  VAL n 
1 61  GLU n 
1 62  PHE n 
1 63  PRO n 
1 64  ILE n 
1 65  TYR n 
1 66  THR n 
1 67  VAL n 
1 68  LEU n 
1 69  ILE n 
1 70  ASP n 
1 71  HIS n 
1 72  PRO n 
1 73  GLU n 
1 74  GLY n 
1 75  LYS n 
1 76  ILE n 
1 77  LEU n 
1 78  PHE n 
1 79  ASP n 
1 80  THR n 
1 81  SER n 
1 82  CYS n 
1 83  ASN n 
1 84  PRO n 
1 85  ASN n 
1 86  SER n 
1 87  MET n 
1 88  GLY n 
1 89  PRO n 
1 90  GLN n 
1 91  GLY n 
1 92  ARG n 
1 93  TRP n 
1 94  ALA n 
1 95  GLU n 
1 96  SER n 
1 97  THR n 
1 98  GLN n 
1 99  GLN n 
1 100 MET n 
1 101 PHE n 
1 102 PRO n 
1 103 TRP n 
1 104 THR n 
1 105 ALA n 
1 106 THR n 
1 107 GLU n 
1 108 GLU n 
1 109 CYS n 
1 110 TYR n 
1 111 LEU n 
1 112 HIS n 
1 113 ASN n 
1 114 ARG n 
1 115 LEU n 
1 116 GLU n 
1 117 GLN n 
1 118 LEU n 
1 119 LYS n 
1 120 VAL n 
1 121 ARG n 
1 122 PRO n 
1 123 GLU n 
1 124 ASP n 
1 125 ILE n 
1 126 ARG n 
1 127 TYR n 
1 128 VAL n 
1 129 VAL n 
1 130 ALA n 
1 131 SER n 
1 132 HIS n 
1 133 LEU n 
1 134 HIS n 
1 135 LEU n 
1 136 ASP n 
1 137 HIS n 
1 138 ALA n 
1 139 GLY n 
1 140 CYS n 
1 141 LEU n 
1 142 GLU n 
1 143 MET n 
1 144 PHE n 
1 145 THR n 
1 146 ASN n 
1 147 ALA n 
1 148 THR n 
1 149 ILE n 
1 150 ILE n 
1 151 VAL n 
1 152 HIS n 
1 153 GLU n 
1 154 ASP n 
1 155 GLU n 
1 156 PHE n 
1 157 ASN n 
1 158 GLY n 
1 159 ALA n 
1 160 LEU n 
1 161 GLN n 
1 162 CYS n 
1 163 TYR n 
1 164 ALA n 
1 165 ARG n 
1 166 ASN n 
1 167 GLN n 
1 168 LYS n 
1 169 GLU n 
1 170 GLY n 
1 171 ALA n 
1 172 TYR n 
1 173 ILE n 
1 174 TRP n 
1 175 ALA n 
1 176 ASP n 
1 177 ILE n 
1 178 ASP n 
1 179 ALA n 
1 180 TRP n 
1 181 ILE n 
1 182 LYS n 
1 183 ASN n 
1 184 ASN n 
1 185 LEU n 
1 186 GLN n 
1 187 TRP n 
1 188 ARG n 
1 189 THR n 
1 190 VAL n 
1 191 LYS n 
1 192 ARG n 
1 193 HIS n 
1 194 GLU n 
1 195 ASP n 
1 196 ASN n 
1 197 ILE n 
1 198 LEU n 
1 199 LEU n 
1 200 ALA n 
1 201 GLU n 
1 202 GLY n 
1 203 VAL n 
1 204 LYS n 
1 205 VAL n 
1 206 LEU n 
1 207 ASN n 
1 208 PHE n 
1 209 GLY n 
1 210 SER n 
1 211 GLY n 
1 212 HIS n 
1 213 ALA n 
1 214 TRP n 
1 215 GLY n 
1 216 MET n 
1 217 LEU n 
1 218 GLY n 
1 219 LEU n 
1 220 HIS n 
1 221 VAL n 
1 222 GLU n 
1 223 LEU n 
1 224 PRO n 
1 225 GLU n 
1 226 THR n 
1 227 GLY n 
1 228 GLY n 
1 229 ILE n 
1 230 ILE n 
1 231 LEU n 
1 232 ALA n 
1 233 SER n 
1 234 ASP n 
1 235 ALA n 
1 236 ILE n 
1 237 TYR n 
1 238 THR n 
1 239 ALA n 
1 240 GLU n 
1 241 SER n 
1 242 TYR n 
1 243 GLY n 
1 244 PRO n 
1 245 PRO n 
1 246 ILE n 
1 247 LYS n 
1 248 PRO n 
1 249 PRO n 
1 250 GLY n 
1 251 ILE n 
1 252 ILE n 
1 253 TYR n 
1 254 ASP n 
1 255 SER n 
1 256 LEU n 
1 257 GLY n 
1 258 TYR n 
1 259 MET n 
1 260 ASN n 
1 261 THR n 
1 262 VAL n 
1 263 GLU n 
1 264 ARG n 
1 265 ILE n 
1 266 ARG n 
1 267 ARG n 
1 268 ILE n 
1 269 ALA n 
1 270 GLN n 
1 271 GLU n 
1 272 THR n 
1 273 LYS n 
1 274 SER n 
1 275 GLN n 
1 276 VAL n 
1 277 TRP n 
1 278 PHE n 
1 279 GLY n 
1 280 HIS n 
1 281 ASP n 
1 282 ALA n 
1 283 GLU n 
1 284 GLN n 
1 285 PHE n 
1 286 LYS n 
1 287 LYS n 
1 288 PHE n 
1 289 ARG n 
1 290 LYS n 
1 291 SER n 
1 292 THR n 
1 293 GLU n 
1 294 GLY n 
1 295 TYR n 
1 296 TYR n 
1 297 GLU n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   297 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 GCA01S_030_00190 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Parageobacillus caldoxylosilyticus' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     81408 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1AI3 non-polymer         . N-octanoyl-L-homoserine ? 'C12 H23 N O4'   245.315 
ALA   'L-peptide linking' y ALANINE                 ? 'C3 H7 N O2'     89.093  
ARG   'L-peptide linking' y ARGININE                ? 'C6 H15 N4 O2 1' 175.209 
ASN   'L-peptide linking' y ASPARAGINE              ? 'C4 H8 N2 O3'    132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID'         ? 'C4 H7 N O4'     133.103 
CO    non-polymer         . 'COBALT (II) ION'       ? 'Co 2'           58.933  
CYS   'L-peptide linking' y CYSTEINE                ? 'C3 H7 N O2 S'   121.158 
FE    non-polymer         . 'FE (III) ION'          ? 'Fe 3'           55.845  
GLN   'L-peptide linking' y GLUTAMINE               ? 'C5 H10 N2 O3'   146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID'         ? 'C5 H9 N O4'     147.129 
GLY   'peptide linking'   y GLYCINE                 ? 'C2 H5 N O2'     75.067  
HIS   'L-peptide linking' y HISTIDINE               ? 'C6 H10 N3 O2 1' 156.162 
HOH   non-polymer         . WATER                   ? 'H2 O'           18.015  
ILE   'L-peptide linking' y ISOLEUCINE              ? 'C6 H13 N O2'    131.173 
LEU   'L-peptide linking' y LEUCINE                 ? 'C6 H13 N O2'    131.173 
LYS   'L-peptide linking' y LYSINE                  ? 'C6 H15 N2 O2 1' 147.195 
MET   'L-peptide linking' y METHIONINE              ? 'C5 H11 N O2 S'  149.211 
PHE   'L-peptide linking' y PHENYLALANINE           ? 'C9 H11 N O2'    165.189 
PRO   'L-peptide linking' y PROLINE                 ? 'C5 H9 N O2'     115.130 
SER   'L-peptide linking' y SERINE                  ? 'C3 H7 N O3'     105.093 
SO4   non-polymer         . 'SULFATE ION'           ? 'O4 S -2'        96.063  
THR   'L-peptide linking' y THREONINE               ? 'C4 H9 N O3'     119.119 
TRP   'L-peptide linking' y TRYPTOPHAN              ? 'C11 H12 N2 O2'  204.225 
TYR   'L-peptide linking' y TYROSINE                ? 'C9 H11 N O3'    181.189 
VAL   'L-peptide linking' y VALINE                  ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   TRP 1   -13 ?   ?   ?   X . n 
A 1 2   SER 2   -12 ?   ?   ?   X . n 
A 1 3   HIS 3   -11 ?   ?   ?   X . n 
A 1 4   PRO 4   -10 ?   ?   ?   X . n 
A 1 5   GLN 5   -9  ?   ?   ?   X . n 
A 1 6   PHE 6   -8  ?   ?   ?   X . n 
A 1 7   GLU 7   -7  ?   ?   ?   X . n 
A 1 8   LYS 8   -6  ?   ?   ?   X . n 
A 1 9   GLU 9   -5  ?   ?   ?   X . n 
A 1 10  ASN 10  -4  ?   ?   ?   X . n 
A 1 11  LEU 11  -3  ?   ?   ?   X . n 
A 1 12  TYR 12  -2  ?   ?   ?   X . n 
A 1 13  PHE 13  -1  ?   ?   ?   X . n 
A 1 14  GLN 14  0   ?   ?   ?   X . n 
A 1 15  SER 15  1   ?   ?   ?   X . n 
A 1 16  MET 16  2   ?   ?   ?   X . n 
A 1 17  ALA 17  3   ?   ?   ?   X . n 
A 1 18  ASN 18  4   ?   ?   ?   X . n 
A 1 19  VAL 19  5   ?   ?   ?   X . n 
A 1 20  ILE 20  6   ?   ?   ?   X . n 
A 1 21  LYS 21  7   ?   ?   ?   X . n 
A 1 22  ALA 22  8   8   ALA ALA X . n 
A 1 23  ARG 23  9   9   ARG ARG X . n 
A 1 24  PRO 24  10  10  PRO PRO X . n 
A 1 25  LYS 25  11  11  LYS LYS X . n 
A 1 26  LEU 26  12  12  LEU LEU X . n 
A 1 27  TYR 27  13  13  TYR TYR X . n 
A 1 28  VAL 28  14  14  VAL VAL X . n 
A 1 29  MET 29  15  15  MET MET X . n 
A 1 30  ASP 30  16  16  ASP ASP X . n 
A 1 31  ASN 31  17  17  ASN ASN X . n 
A 1 32  GLY 32  18  18  GLY GLY X . n 
A 1 33  ARG 33  19  19  ARG ARG X . n 
A 1 34  MET 34  20  20  MET MET X . n 
A 1 35  ARG 35  21  21  ARG ARG X . n 
A 1 36  MET 36  22  22  MET MET X . n 
A 1 37  ASP 37  23  23  ASP ASP X . n 
A 1 38  LYS 38  24  24  LYS LYS X . n 
A 1 39  ASN 39  25  25  ASN ASN X . n 
A 1 40  TRP 40  26  26  TRP TRP X . n 
A 1 41  MET 41  27  27  MET MET X . n 
A 1 42  ILE 42  28  28  ILE ILE X . n 
A 1 43  ALA 43  29  29  ALA ALA X . n 
A 1 44  MET 44  30  30  MET MET X . n 
A 1 45  HIS 45  31  31  HIS HIS X . n 
A 1 46  ASN 46  32  32  ASN ASN X . n 
A 1 47  PRO 47  33  33  PRO PRO X . n 
A 1 48  ALA 48  34  34  ALA ALA X . n 
A 1 49  THR 49  35  35  THR THR X . n 
A 1 50  ILE 50  36  36  ILE ILE X . n 
A 1 51  HIS 51  37  37  HIS HIS X . n 
A 1 52  ASN 52  38  38  ASN ASN X . n 
A 1 53  PRO 53  39  39  PRO PRO X . n 
A 1 54  ASN 54  40  40  ASN ASN X . n 
A 1 55  ALA 55  41  41  ALA ALA X . n 
A 1 56  GLN 56  42  42  GLN GLN X . n 
A 1 57  THR 57  43  43  THR THR X . n 
A 1 58  GLU 58  44  44  GLU GLU X . n 
A 1 59  PHE 59  45  45  PHE PHE X . n 
A 1 60  VAL 60  46  46  VAL VAL X . n 
A 1 61  GLU 61  47  47  GLU GLU X . n 
A 1 62  PHE 62  48  48  PHE PHE X . n 
A 1 63  PRO 63  49  49  PRO PRO X . n 
A 1 64  ILE 64  50  50  ILE ILE X . n 
A 1 65  TYR 65  51  51  TYR TYR X . n 
A 1 66  THR 66  52  52  THR THR X . n 
A 1 67  VAL 67  53  53  VAL VAL X . n 
A 1 68  LEU 68  54  54  LEU LEU X . n 
A 1 69  ILE 69  55  55  ILE ILE X . n 
A 1 70  ASP 70  56  56  ASP ASP X . n 
A 1 71  HIS 71  57  57  HIS HIS X . n 
A 1 72  PRO 72  58  58  PRO PRO X . n 
A 1 73  GLU 73  59  59  GLU GLU X . n 
A 1 74  GLY 74  60  60  GLY GLY X . n 
A 1 75  LYS 75  61  61  LYS LYS X . n 
A 1 76  ILE 76  62  62  ILE ILE X . n 
A 1 77  LEU 77  63  63  LEU LEU X . n 
A 1 78  PHE 78  64  64  PHE PHE X . n 
A 1 79  ASP 79  65  65  ASP ASP X . n 
A 1 80  THR 80  66  66  THR THR X . n 
A 1 81  SER 81  67  67  SER SER X . n 
A 1 82  CYS 82  68  68  CYS CYS X . n 
A 1 83  ASN 83  69  69  ASN ASN X . n 
A 1 84  PRO 84  70  70  PRO PRO X . n 
A 1 85  ASN 85  71  71  ASN ASN X . n 
A 1 86  SER 86  72  72  SER SER X . n 
A 1 87  MET 87  73  73  MET MET X . n 
A 1 88  GLY 88  74  74  GLY GLY X . n 
A 1 89  PRO 89  75  75  PRO PRO X . n 
A 1 90  GLN 90  76  76  GLN GLN X . n 
A 1 91  GLY 91  77  77  GLY GLY X . n 
A 1 92  ARG 92  78  78  ARG ARG X . n 
A 1 93  TRP 93  79  79  TRP TRP X . n 
A 1 94  ALA 94  80  80  ALA ALA X . n 
A 1 95  GLU 95  81  81  GLU GLU X . n 
A 1 96  SER 96  82  82  SER SER X . n 
A 1 97  THR 97  83  83  THR THR X . n 
A 1 98  GLN 98  84  84  GLN GLN X . n 
A 1 99  GLN 99  85  85  GLN GLN X . n 
A 1 100 MET 100 86  86  MET MET X . n 
A 1 101 PHE 101 87  87  PHE PHE X . n 
A 1 102 PRO 102 88  88  PRO PRO X . n 
A 1 103 TRP 103 89  89  TRP TRP X . n 
A 1 104 THR 104 90  90  THR THR X . n 
A 1 105 ALA 105 91  91  ALA ALA X . n 
A 1 106 THR 106 92  92  THR THR X . n 
A 1 107 GLU 107 93  93  GLU GLU X . n 
A 1 108 GLU 108 94  94  GLU GLU X . n 
A 1 109 CYS 109 95  95  CYS CYS X . n 
A 1 110 TYR 110 96  96  TYR TYR X . n 
A 1 111 LEU 111 97  97  LEU LEU X . n 
A 1 112 HIS 112 98  98  HIS HIS X . n 
A 1 113 ASN 113 99  99  ASN ASN X . n 
A 1 114 ARG 114 100 100 ARG ARG X . n 
A 1 115 LEU 115 101 101 LEU LEU X . n 
A 1 116 GLU 116 102 102 GLU GLU X . n 
A 1 117 GLN 117 103 103 GLN GLN X . n 
A 1 118 LEU 118 104 104 LEU LEU X . n 
A 1 119 LYS 119 105 105 LYS LYS X . n 
A 1 120 VAL 120 106 106 VAL VAL X . n 
A 1 121 ARG 121 107 107 ARG ARG X . n 
A 1 122 PRO 122 108 108 PRO PRO X . n 
A 1 123 GLU 123 109 109 GLU GLU X . n 
A 1 124 ASP 124 110 110 ASP ASP X . n 
A 1 125 ILE 125 111 111 ILE ILE X . n 
A 1 126 ARG 126 112 112 ARG ARG X . n 
A 1 127 TYR 127 113 113 TYR TYR X . n 
A 1 128 VAL 128 114 114 VAL VAL X . n 
A 1 129 VAL 129 115 115 VAL VAL X . n 
A 1 130 ALA 130 116 116 ALA ALA X . n 
A 1 131 SER 131 117 117 SER SER X . n 
A 1 132 HIS 132 118 118 HIS HIS X . n 
A 1 133 LEU 133 119 119 LEU LEU X . n 
A 1 134 HIS 134 120 120 HIS HIS X . n 
A 1 135 LEU 135 121 121 LEU LEU X . n 
A 1 136 ASP 136 122 122 ASP ASP X . n 
A 1 137 HIS 137 123 123 HIS HIS X . n 
A 1 138 ALA 138 124 124 ALA ALA X . n 
A 1 139 GLY 139 125 125 GLY GLY X . n 
A 1 140 CYS 140 126 126 CYS CYS X . n 
A 1 141 LEU 141 127 127 LEU LEU X . n 
A 1 142 GLU 142 128 128 GLU GLU X . n 
A 1 143 MET 143 129 129 MET MET X . n 
A 1 144 PHE 144 130 130 PHE PHE X . n 
A 1 145 THR 145 131 131 THR THR X . n 
A 1 146 ASN 146 132 132 ASN ASN X . n 
A 1 147 ALA 147 133 133 ALA ALA X . n 
A 1 148 THR 148 134 134 THR THR X . n 
A 1 149 ILE 149 135 135 ILE ILE X . n 
A 1 150 ILE 150 136 136 ILE ILE X . n 
A 1 151 VAL 151 137 137 VAL VAL X . n 
A 1 152 HIS 152 138 138 HIS HIS X . n 
A 1 153 GLU 153 139 139 GLU GLU X . n 
A 1 154 ASP 154 140 140 ASP ASP X . n 
A 1 155 GLU 155 141 141 GLU GLU X . n 
A 1 156 PHE 156 142 142 PHE PHE X . n 
A 1 157 ASN 157 143 143 ASN ASN X . n 
A 1 158 GLY 158 144 144 GLY GLY X . n 
A 1 159 ALA 159 145 145 ALA ALA X . n 
A 1 160 LEU 160 146 146 LEU LEU X . n 
A 1 161 GLN 161 147 147 GLN GLN X . n 
A 1 162 CYS 162 148 148 CYS CYS X . n 
A 1 163 TYR 163 149 149 TYR TYR X . n 
A 1 164 ALA 164 150 150 ALA ALA X . n 
A 1 165 ARG 165 151 151 ARG ARG X . n 
A 1 166 ASN 166 152 152 ASN ASN X . n 
A 1 167 GLN 167 153 153 GLN GLN X . n 
A 1 168 LYS 168 154 154 LYS LYS X . n 
A 1 169 GLU 169 155 155 GLU GLU X . n 
A 1 170 GLY 170 156 156 GLY GLY X . n 
A 1 171 ALA 171 157 157 ALA ALA X . n 
A 1 172 TYR 172 158 158 TYR TYR X . n 
A 1 173 ILE 173 159 159 ILE ILE X . n 
A 1 174 TRP 174 160 160 TRP TRP X . n 
A 1 175 ALA 175 161 161 ALA ALA X . n 
A 1 176 ASP 176 162 162 ASP ASP X . n 
A 1 177 ILE 177 163 163 ILE ILE X . n 
A 1 178 ASP 178 164 164 ASP ASP X . n 
A 1 179 ALA 179 165 165 ALA ALA X . n 
A 1 180 TRP 180 166 166 TRP TRP X . n 
A 1 181 ILE 181 167 167 ILE ILE X . n 
A 1 182 LYS 182 168 168 LYS LYS X . n 
A 1 183 ASN 183 169 169 ASN ASN X . n 
A 1 184 ASN 184 170 170 ASN ASN X . n 
A 1 185 LEU 185 171 171 LEU LEU X . n 
A 1 186 GLN 186 172 172 GLN GLN X . n 
A 1 187 TRP 187 173 173 TRP TRP X . n 
A 1 188 ARG 188 174 174 ARG ARG X . n 
A 1 189 THR 189 175 175 THR THR X . n 
A 1 190 VAL 190 176 176 VAL VAL X . n 
A 1 191 LYS 191 177 177 LYS LYS X . n 
A 1 192 ARG 192 178 178 ARG ARG X . n 
A 1 193 HIS 193 179 179 HIS HIS X . n 
A 1 194 GLU 194 180 180 GLU GLU X . n 
A 1 195 ASP 195 181 181 ASP ASP X . n 
A 1 196 ASN 196 182 182 ASN ASN X . n 
A 1 197 ILE 197 183 183 ILE ILE X . n 
A 1 198 LEU 198 184 184 LEU LEU X . n 
A 1 199 LEU 199 185 185 LEU LEU X . n 
A 1 200 ALA 200 186 186 ALA ALA X . n 
A 1 201 GLU 201 187 187 GLU GLU X . n 
A 1 202 GLY 202 188 188 GLY GLY X . n 
A 1 203 VAL 203 189 189 VAL VAL X . n 
A 1 204 LYS 204 190 190 LYS LYS X . n 
A 1 205 VAL 205 191 191 VAL VAL X . n 
A 1 206 LEU 206 192 192 LEU LEU X . n 
A 1 207 ASN 207 193 193 ASN ASN X . n 
A 1 208 PHE 208 194 194 PHE PHE X . n 
A 1 209 GLY 209 195 195 GLY GLY X . n 
A 1 210 SER 210 196 196 SER SER X . n 
A 1 211 GLY 211 197 197 GLY GLY X . n 
A 1 212 HIS 212 198 198 HIS HIS X . n 
A 1 213 ALA 213 199 199 ALA ALA X . n 
A 1 214 TRP 214 200 200 TRP TRP X . n 
A 1 215 GLY 215 201 201 GLY GLY X . n 
A 1 216 MET 216 202 202 MET MET X . n 
A 1 217 LEU 217 203 203 LEU LEU X . n 
A 1 218 GLY 218 204 204 GLY GLY X . n 
A 1 219 LEU 219 205 205 LEU LEU X . n 
A 1 220 HIS 220 206 206 HIS HIS X . n 
A 1 221 VAL 221 207 207 VAL VAL X . n 
A 1 222 GLU 222 208 208 GLU GLU X . n 
A 1 223 LEU 223 209 209 LEU LEU X . n 
A 1 224 PRO 224 210 210 PRO PRO X . n 
A 1 225 GLU 225 211 211 GLU GLU X . n 
A 1 226 THR 226 212 212 THR THR X . n 
A 1 227 GLY 227 213 213 GLY GLY X . n 
A 1 228 GLY 228 214 214 GLY GLY X . n 
A 1 229 ILE 229 215 215 ILE ILE X . n 
A 1 230 ILE 230 216 216 ILE ILE X . n 
A 1 231 LEU 231 217 217 LEU LEU X . n 
A 1 232 ALA 232 218 218 ALA ALA X . n 
A 1 233 SER 233 219 219 SER SER X . n 
A 1 234 ASP 234 220 220 ASP ASP X . n 
A 1 235 ALA 235 221 221 ALA ALA X . n 
A 1 236 ILE 236 222 222 ILE ILE X . n 
A 1 237 TYR 237 223 223 TYR TYR X . n 
A 1 238 THR 238 224 224 THR THR X . n 
A 1 239 ALA 239 225 225 ALA ALA X . n 
A 1 240 GLU 240 226 226 GLU GLU X . n 
A 1 241 SER 241 227 227 SER SER X . n 
A 1 242 TYR 242 228 228 TYR TYR X . n 
A 1 243 GLY 243 229 229 GLY GLY X . n 
A 1 244 PRO 244 230 230 PRO PRO X . n 
A 1 245 PRO 245 231 231 PRO PRO X . n 
A 1 246 ILE 246 232 232 ILE ILE X . n 
A 1 247 LYS 247 233 233 LYS LYS X . n 
A 1 248 PRO 248 234 234 PRO PRO X . n 
A 1 249 PRO 249 235 235 PRO PRO X . n 
A 1 250 GLY 250 236 236 GLY GLY X . n 
A 1 251 ILE 251 237 237 ILE ILE X . n 
A 1 252 ILE 252 238 238 ILE ILE X . n 
A 1 253 TYR 253 239 239 TYR TYR X . n 
A 1 254 ASP 254 240 240 ASP ASP X . n 
A 1 255 SER 255 241 241 SER SER X . n 
A 1 256 LEU 256 242 242 LEU LEU X . n 
A 1 257 GLY 257 243 243 GLY GLY X . n 
A 1 258 TYR 258 244 244 TYR TYR X . n 
A 1 259 MET 259 245 245 MET MET X . n 
A 1 260 ASN 260 246 246 ASN ASN X . n 
A 1 261 THR 261 247 247 THR THR X . n 
A 1 262 VAL 262 248 248 VAL VAL X . n 
A 1 263 GLU 263 249 249 GLU GLU X . n 
A 1 264 ARG 264 250 250 ARG ARG X . n 
A 1 265 ILE 265 251 251 ILE ILE X . n 
A 1 266 ARG 266 252 252 ARG ARG X . n 
A 1 267 ARG 267 253 253 ARG ARG X . n 
A 1 268 ILE 268 254 254 ILE ILE X . n 
A 1 269 ALA 269 255 255 ALA ALA X . n 
A 1 270 GLN 270 256 256 GLN GLN X . n 
A 1 271 GLU 271 257 257 GLU GLU X . n 
A 1 272 THR 272 258 258 THR THR X . n 
A 1 273 LYS 273 259 259 LYS LYS X . n 
A 1 274 SER 274 260 260 SER SER X . n 
A 1 275 GLN 275 261 261 GLN GLN X . n 
A 1 276 VAL 276 262 262 VAL VAL X . n 
A 1 277 TRP 277 263 263 TRP TRP X . n 
A 1 278 PHE 278 264 264 PHE PHE X . n 
A 1 279 GLY 279 265 265 GLY GLY X . n 
A 1 280 HIS 280 266 266 HIS HIS X . n 
A 1 281 ASP 281 267 267 ASP ASP X . n 
A 1 282 ALA 282 268 268 ALA ALA X . n 
A 1 283 GLU 283 269 269 GLU GLU X . n 
A 1 284 GLN 284 270 270 GLN GLN X . n 
A 1 285 PHE 285 271 271 PHE PHE X . n 
A 1 286 LYS 286 272 272 LYS LYS X . n 
A 1 287 LYS 287 273 273 LYS LYS X . n 
A 1 288 PHE 288 274 274 PHE PHE X . n 
A 1 289 ARG 289 275 275 ARG ARG X . n 
A 1 290 LYS 290 276 276 LYS LYS X . n 
A 1 291 SER 291 277 277 SER SER X . n 
A 1 292 THR 292 278 278 THR THR X . n 
A 1 293 GLU 293 279 279 GLU GLU X . n 
A 1 294 GLY 294 280 280 GLY GLY X . n 
A 1 295 TYR 295 281 281 TYR TYR X . n 
A 1 296 TYR 296 282 282 TYR TYR X . n 
A 1 297 GLU 297 283 283 GLU GLU X . n 
B 1 1   TRP 1   -13 ?   ?   ?   F . n 
B 1 2   SER 2   -12 ?   ?   ?   F . n 
B 1 3   HIS 3   -11 ?   ?   ?   F . n 
B 1 4   PRO 4   -10 ?   ?   ?   F . n 
B 1 5   GLN 5   -9  ?   ?   ?   F . n 
B 1 6   PHE 6   -8  ?   ?   ?   F . n 
B 1 7   GLU 7   -7  ?   ?   ?   F . n 
B 1 8   LYS 8   -6  ?   ?   ?   F . n 
B 1 9   GLU 9   -5  ?   ?   ?   F . n 
B 1 10  ASN 10  -4  ?   ?   ?   F . n 
B 1 11  LEU 11  -3  ?   ?   ?   F . n 
B 1 12  TYR 12  -2  ?   ?   ?   F . n 
B 1 13  PHE 13  -1  ?   ?   ?   F . n 
B 1 14  GLN 14  0   ?   ?   ?   F . n 
B 1 15  SER 15  1   ?   ?   ?   F . n 
B 1 16  MET 16  2   ?   ?   ?   F . n 
B 1 17  ALA 17  3   ?   ?   ?   F . n 
B 1 18  ASN 18  4   ?   ?   ?   F . n 
B 1 19  VAL 19  5   ?   ?   ?   F . n 
B 1 20  ILE 20  6   ?   ?   ?   F . n 
B 1 21  LYS 21  7   ?   ?   ?   F . n 
B 1 22  ALA 22  8   8   ALA ALA F . n 
B 1 23  ARG 23  9   9   ARG ARG F . n 
B 1 24  PRO 24  10  10  PRO PRO F . n 
B 1 25  LYS 25  11  11  LYS LYS F . n 
B 1 26  LEU 26  12  12  LEU LEU F . n 
B 1 27  TYR 27  13  13  TYR TYR F . n 
B 1 28  VAL 28  14  14  VAL VAL F . n 
B 1 29  MET 29  15  15  MET MET F . n 
B 1 30  ASP 30  16  16  ASP ASP F . n 
B 1 31  ASN 31  17  17  ASN ASN F . n 
B 1 32  GLY 32  18  18  GLY GLY F . n 
B 1 33  ARG 33  19  19  ARG ARG F . n 
B 1 34  MET 34  20  20  MET MET F . n 
B 1 35  ARG 35  21  21  ARG ARG F . n 
B 1 36  MET 36  22  22  MET MET F . n 
B 1 37  ASP 37  23  23  ASP ASP F . n 
B 1 38  LYS 38  24  24  LYS LYS F . n 
B 1 39  ASN 39  25  25  ASN ASN F . n 
B 1 40  TRP 40  26  26  TRP TRP F . n 
B 1 41  MET 41  27  27  MET MET F . n 
B 1 42  ILE 42  28  28  ILE ILE F . n 
B 1 43  ALA 43  29  29  ALA ALA F . n 
B 1 44  MET 44  30  30  MET MET F . n 
B 1 45  HIS 45  31  31  HIS HIS F . n 
B 1 46  ASN 46  32  32  ASN ASN F . n 
B 1 47  PRO 47  33  33  PRO PRO F . n 
B 1 48  ALA 48  34  34  ALA ALA F . n 
B 1 49  THR 49  35  35  THR THR F . n 
B 1 50  ILE 50  36  36  ILE ILE F . n 
B 1 51  HIS 51  37  37  HIS HIS F . n 
B 1 52  ASN 52  38  38  ASN ASN F . n 
B 1 53  PRO 53  39  39  PRO PRO F . n 
B 1 54  ASN 54  40  40  ASN ASN F . n 
B 1 55  ALA 55  41  41  ALA ALA F . n 
B 1 56  GLN 56  42  42  GLN GLN F . n 
B 1 57  THR 57  43  43  THR THR F . n 
B 1 58  GLU 58  44  44  GLU GLU F . n 
B 1 59  PHE 59  45  45  PHE PHE F . n 
B 1 60  VAL 60  46  46  VAL VAL F . n 
B 1 61  GLU 61  47  47  GLU GLU F . n 
B 1 62  PHE 62  48  48  PHE PHE F . n 
B 1 63  PRO 63  49  49  PRO PRO F . n 
B 1 64  ILE 64  50  50  ILE ILE F . n 
B 1 65  TYR 65  51  51  TYR TYR F . n 
B 1 66  THR 66  52  52  THR THR F . n 
B 1 67  VAL 67  53  53  VAL VAL F . n 
B 1 68  LEU 68  54  54  LEU LEU F . n 
B 1 69  ILE 69  55  55  ILE ILE F . n 
B 1 70  ASP 70  56  56  ASP ASP F . n 
B 1 71  HIS 71  57  57  HIS HIS F . n 
B 1 72  PRO 72  58  58  PRO PRO F . n 
B 1 73  GLU 73  59  59  GLU GLU F . n 
B 1 74  GLY 74  60  60  GLY GLY F . n 
B 1 75  LYS 75  61  61  LYS LYS F . n 
B 1 76  ILE 76  62  62  ILE ILE F . n 
B 1 77  LEU 77  63  63  LEU LEU F . n 
B 1 78  PHE 78  64  64  PHE PHE F . n 
B 1 79  ASP 79  65  65  ASP ASP F . n 
B 1 80  THR 80  66  66  THR THR F . n 
B 1 81  SER 81  67  67  SER SER F . n 
B 1 82  CYS 82  68  68  CYS CYS F . n 
B 1 83  ASN 83  69  69  ASN ASN F . n 
B 1 84  PRO 84  70  70  PRO PRO F . n 
B 1 85  ASN 85  71  71  ASN ASN F . n 
B 1 86  SER 86  72  72  SER SER F . n 
B 1 87  MET 87  73  73  MET MET F . n 
B 1 88  GLY 88  74  74  GLY GLY F . n 
B 1 89  PRO 89  75  75  PRO PRO F . n 
B 1 90  GLN 90  76  76  GLN GLN F . n 
B 1 91  GLY 91  77  77  GLY GLY F . n 
B 1 92  ARG 92  78  78  ARG ARG F . n 
B 1 93  TRP 93  79  79  TRP TRP F . n 
B 1 94  ALA 94  80  80  ALA ALA F . n 
B 1 95  GLU 95  81  81  GLU GLU F . n 
B 1 96  SER 96  82  82  SER SER F . n 
B 1 97  THR 97  83  83  THR THR F . n 
B 1 98  GLN 98  84  84  GLN GLN F . n 
B 1 99  GLN 99  85  85  GLN GLN F . n 
B 1 100 MET 100 86  86  MET MET F . n 
B 1 101 PHE 101 87  87  PHE PHE F . n 
B 1 102 PRO 102 88  88  PRO PRO F . n 
B 1 103 TRP 103 89  89  TRP TRP F . n 
B 1 104 THR 104 90  90  THR THR F . n 
B 1 105 ALA 105 91  91  ALA ALA F . n 
B 1 106 THR 106 92  92  THR THR F . n 
B 1 107 GLU 107 93  93  GLU GLU F . n 
B 1 108 GLU 108 94  94  GLU GLU F . n 
B 1 109 CYS 109 95  95  CYS CYS F . n 
B 1 110 TYR 110 96  96  TYR TYR F . n 
B 1 111 LEU 111 97  97  LEU LEU F . n 
B 1 112 HIS 112 98  98  HIS HIS F . n 
B 1 113 ASN 113 99  99  ASN ASN F . n 
B 1 114 ARG 114 100 100 ARG ARG F . n 
B 1 115 LEU 115 101 101 LEU LEU F . n 
B 1 116 GLU 116 102 102 GLU GLU F . n 
B 1 117 GLN 117 103 103 GLN GLN F . n 
B 1 118 LEU 118 104 104 LEU LEU F . n 
B 1 119 LYS 119 105 105 LYS LYS F . n 
B 1 120 VAL 120 106 106 VAL VAL F . n 
B 1 121 ARG 121 107 107 ARG ARG F . n 
B 1 122 PRO 122 108 108 PRO PRO F . n 
B 1 123 GLU 123 109 109 GLU GLU F . n 
B 1 124 ASP 124 110 110 ASP ASP F . n 
B 1 125 ILE 125 111 111 ILE ILE F . n 
B 1 126 ARG 126 112 112 ARG ARG F . n 
B 1 127 TYR 127 113 113 TYR TYR F . n 
B 1 128 VAL 128 114 114 VAL VAL F . n 
B 1 129 VAL 129 115 115 VAL VAL F . n 
B 1 130 ALA 130 116 116 ALA ALA F . n 
B 1 131 SER 131 117 117 SER SER F . n 
B 1 132 HIS 132 118 118 HIS HIS F . n 
B 1 133 LEU 133 119 119 LEU LEU F . n 
B 1 134 HIS 134 120 120 HIS HIS F . n 
B 1 135 LEU 135 121 121 LEU LEU F . n 
B 1 136 ASP 136 122 122 ASP ASP F . n 
B 1 137 HIS 137 123 123 HIS HIS F . n 
B 1 138 ALA 138 124 124 ALA ALA F . n 
B 1 139 GLY 139 125 125 GLY GLY F . n 
B 1 140 CYS 140 126 126 CYS CYS F . n 
B 1 141 LEU 141 127 127 LEU LEU F . n 
B 1 142 GLU 142 128 128 GLU GLU F . n 
B 1 143 MET 143 129 129 MET MET F . n 
B 1 144 PHE 144 130 130 PHE PHE F . n 
B 1 145 THR 145 131 131 THR THR F . n 
B 1 146 ASN 146 132 132 ASN ASN F . n 
B 1 147 ALA 147 133 133 ALA ALA F . n 
B 1 148 THR 148 134 134 THR THR F . n 
B 1 149 ILE 149 135 135 ILE ILE F . n 
B 1 150 ILE 150 136 136 ILE ILE F . n 
B 1 151 VAL 151 137 137 VAL VAL F . n 
B 1 152 HIS 152 138 138 HIS HIS F . n 
B 1 153 GLU 153 139 139 GLU GLU F . n 
B 1 154 ASP 154 140 140 ASP ASP F . n 
B 1 155 GLU 155 141 141 GLU GLU F . n 
B 1 156 PHE 156 142 142 PHE PHE F . n 
B 1 157 ASN 157 143 143 ASN ASN F . n 
B 1 158 GLY 158 144 144 GLY GLY F . n 
B 1 159 ALA 159 145 145 ALA ALA F . n 
B 1 160 LEU 160 146 146 LEU LEU F . n 
B 1 161 GLN 161 147 147 GLN GLN F . n 
B 1 162 CYS 162 148 148 CYS CYS F . n 
B 1 163 TYR 163 149 149 TYR TYR F . n 
B 1 164 ALA 164 150 150 ALA ALA F . n 
B 1 165 ARG 165 151 151 ARG ARG F . n 
B 1 166 ASN 166 152 152 ASN ASN F . n 
B 1 167 GLN 167 153 153 GLN GLN F . n 
B 1 168 LYS 168 154 154 LYS LYS F . n 
B 1 169 GLU 169 155 155 GLU GLU F . n 
B 1 170 GLY 170 156 156 GLY GLY F . n 
B 1 171 ALA 171 157 157 ALA ALA F . n 
B 1 172 TYR 172 158 158 TYR TYR F . n 
B 1 173 ILE 173 159 159 ILE ILE F . n 
B 1 174 TRP 174 160 160 TRP TRP F . n 
B 1 175 ALA 175 161 161 ALA ALA F . n 
B 1 176 ASP 176 162 162 ASP ASP F . n 
B 1 177 ILE 177 163 163 ILE ILE F . n 
B 1 178 ASP 178 164 164 ASP ASP F . n 
B 1 179 ALA 179 165 165 ALA ALA F . n 
B 1 180 TRP 180 166 166 TRP TRP F . n 
B 1 181 ILE 181 167 167 ILE ILE F . n 
B 1 182 LYS 182 168 168 LYS LYS F . n 
B 1 183 ASN 183 169 169 ASN ASN F . n 
B 1 184 ASN 184 170 170 ASN ASN F . n 
B 1 185 LEU 185 171 171 LEU LEU F . n 
B 1 186 GLN 186 172 172 GLN GLN F . n 
B 1 187 TRP 187 173 173 TRP TRP F . n 
B 1 188 ARG 188 174 174 ARG ARG F . n 
B 1 189 THR 189 175 175 THR THR F . n 
B 1 190 VAL 190 176 176 VAL VAL F . n 
B 1 191 LYS 191 177 177 LYS LYS F . n 
B 1 192 ARG 192 178 178 ARG ARG F . n 
B 1 193 HIS 193 179 179 HIS HIS F . n 
B 1 194 GLU 194 180 180 GLU GLU F . n 
B 1 195 ASP 195 181 181 ASP ASP F . n 
B 1 196 ASN 196 182 182 ASN ASN F . n 
B 1 197 ILE 197 183 183 ILE ILE F . n 
B 1 198 LEU 198 184 184 LEU LEU F . n 
B 1 199 LEU 199 185 185 LEU LEU F . n 
B 1 200 ALA 200 186 186 ALA ALA F . n 
B 1 201 GLU 201 187 187 GLU GLU F . n 
B 1 202 GLY 202 188 188 GLY GLY F . n 
B 1 203 VAL 203 189 189 VAL VAL F . n 
B 1 204 LYS 204 190 190 LYS LYS F . n 
B 1 205 VAL 205 191 191 VAL VAL F . n 
B 1 206 LEU 206 192 192 LEU LEU F . n 
B 1 207 ASN 207 193 193 ASN ASN F . n 
B 1 208 PHE 208 194 194 PHE PHE F . n 
B 1 209 GLY 209 195 195 GLY GLY F . n 
B 1 210 SER 210 196 196 SER SER F . n 
B 1 211 GLY 211 197 197 GLY GLY F . n 
B 1 212 HIS 212 198 198 HIS HIS F . n 
B 1 213 ALA 213 199 199 ALA ALA F . n 
B 1 214 TRP 214 200 200 TRP TRP F . n 
B 1 215 GLY 215 201 201 GLY GLY F . n 
B 1 216 MET 216 202 202 MET MET F . n 
B 1 217 LEU 217 203 203 LEU LEU F . n 
B 1 218 GLY 218 204 204 GLY GLY F . n 
B 1 219 LEU 219 205 205 LEU LEU F . n 
B 1 220 HIS 220 206 206 HIS HIS F . n 
B 1 221 VAL 221 207 207 VAL VAL F . n 
B 1 222 GLU 222 208 208 GLU GLU F . n 
B 1 223 LEU 223 209 209 LEU LEU F . n 
B 1 224 PRO 224 210 210 PRO PRO F . n 
B 1 225 GLU 225 211 211 GLU GLU F . n 
B 1 226 THR 226 212 212 THR THR F . n 
B 1 227 GLY 227 213 213 GLY GLY F . n 
B 1 228 GLY 228 214 214 GLY GLY F . n 
B 1 229 ILE 229 215 215 ILE ILE F . n 
B 1 230 ILE 230 216 216 ILE ILE F . n 
B 1 231 LEU 231 217 217 LEU LEU F . n 
B 1 232 ALA 232 218 218 ALA ALA F . n 
B 1 233 SER 233 219 219 SER SER F . n 
B 1 234 ASP 234 220 220 ASP ASP F . n 
B 1 235 ALA 235 221 221 ALA ALA F . n 
B 1 236 ILE 236 222 222 ILE ILE F . n 
B 1 237 TYR 237 223 223 TYR TYR F . n 
B 1 238 THR 238 224 224 THR THR F . n 
B 1 239 ALA 239 225 225 ALA ALA F . n 
B 1 240 GLU 240 226 226 GLU GLU F . n 
B 1 241 SER 241 227 227 SER SER F . n 
B 1 242 TYR 242 228 228 TYR TYR F . n 
B 1 243 GLY 243 229 229 GLY GLY F . n 
B 1 244 PRO 244 230 230 PRO PRO F . n 
B 1 245 PRO 245 231 231 PRO PRO F . n 
B 1 246 ILE 246 232 232 ILE ILE F . n 
B 1 247 LYS 247 233 233 LYS LYS F . n 
B 1 248 PRO 248 234 234 PRO PRO F . n 
B 1 249 PRO 249 235 235 PRO PRO F . n 
B 1 250 GLY 250 236 236 GLY GLY F . n 
B 1 251 ILE 251 237 237 ILE ILE F . n 
B 1 252 ILE 252 238 238 ILE ILE F . n 
B 1 253 TYR 253 239 239 TYR TYR F . n 
B 1 254 ASP 254 240 240 ASP ASP F . n 
B 1 255 SER 255 241 241 SER SER F . n 
B 1 256 LEU 256 242 242 LEU LEU F . n 
B 1 257 GLY 257 243 243 GLY GLY F . n 
B 1 258 TYR 258 244 244 TYR TYR F . n 
B 1 259 MET 259 245 245 MET MET F . n 
B 1 260 ASN 260 246 246 ASN ASN F . n 
B 1 261 THR 261 247 247 THR THR F . n 
B 1 262 VAL 262 248 248 VAL VAL F . n 
B 1 263 GLU 263 249 249 GLU GLU F . n 
B 1 264 ARG 264 250 250 ARG ARG F . n 
B 1 265 ILE 265 251 251 ILE ILE F . n 
B 1 266 ARG 266 252 252 ARG ARG F . n 
B 1 267 ARG 267 253 253 ARG ARG F . n 
B 1 268 ILE 268 254 254 ILE ILE F . n 
B 1 269 ALA 269 255 255 ALA ALA F . n 
B 1 270 GLN 270 256 256 GLN GLN F . n 
B 1 271 GLU 271 257 257 GLU GLU F . n 
B 1 272 THR 272 258 258 THR THR F . n 
B 1 273 LYS 273 259 259 LYS LYS F . n 
B 1 274 SER 274 260 260 SER SER F . n 
B 1 275 GLN 275 261 261 GLN GLN F . n 
B 1 276 VAL 276 262 262 VAL VAL F . n 
B 1 277 TRP 277 263 263 TRP TRP F . n 
B 1 278 PHE 278 264 264 PHE PHE F . n 
B 1 279 GLY 279 265 265 GLY GLY F . n 
B 1 280 HIS 280 266 266 HIS HIS F . n 
B 1 281 ASP 281 267 267 ASP ASP F . n 
B 1 282 ALA 282 268 268 ALA ALA F . n 
B 1 283 GLU 283 269 269 GLU GLU F . n 
B 1 284 GLN 284 270 270 GLN GLN F . n 
B 1 285 PHE 285 271 271 PHE PHE F . n 
B 1 286 LYS 286 272 272 LYS LYS F . n 
B 1 287 LYS 287 273 273 LYS LYS F . n 
B 1 288 PHE 288 274 274 PHE PHE F . n 
B 1 289 ARG 289 275 275 ARG ARG F . n 
B 1 290 LYS 290 276 276 LYS LYS F . n 
B 1 291 SER 291 277 277 SER SER F . n 
B 1 292 THR 292 278 278 THR THR F . n 
B 1 293 GLU 293 279 279 GLU GLU F . n 
B 1 294 GLY 294 280 280 GLY GLY F . n 
B 1 295 TYR 295 281 281 TYR TYR F . n 
B 1 296 TYR 296 282 282 TYR TYR F . n 
B 1 297 GLU 297 283 283 GLU GLU F . n 
C 1 1   TRP 1   -13 ?   ?   ?   L . n 
C 1 2   SER 2   -12 ?   ?   ?   L . n 
C 1 3   HIS 3   -11 ?   ?   ?   L . n 
C 1 4   PRO 4   -10 ?   ?   ?   L . n 
C 1 5   GLN 5   -9  ?   ?   ?   L . n 
C 1 6   PHE 6   -8  ?   ?   ?   L . n 
C 1 7   GLU 7   -7  ?   ?   ?   L . n 
C 1 8   LYS 8   -6  ?   ?   ?   L . n 
C 1 9   GLU 9   -5  ?   ?   ?   L . n 
C 1 10  ASN 10  -4  ?   ?   ?   L . n 
C 1 11  LEU 11  -3  ?   ?   ?   L . n 
C 1 12  TYR 12  -2  ?   ?   ?   L . n 
C 1 13  PHE 13  -1  ?   ?   ?   L . n 
C 1 14  GLN 14  0   ?   ?   ?   L . n 
C 1 15  SER 15  1   ?   ?   ?   L . n 
C 1 16  MET 16  2   ?   ?   ?   L . n 
C 1 17  ALA 17  3   ?   ?   ?   L . n 
C 1 18  ASN 18  4   ?   ?   ?   L . n 
C 1 19  VAL 19  5   ?   ?   ?   L . n 
C 1 20  ILE 20  6   ?   ?   ?   L . n 
C 1 21  LYS 21  7   ?   ?   ?   L . n 
C 1 22  ALA 22  8   8   ALA ALA L . n 
C 1 23  ARG 23  9   9   ARG ARG L . n 
C 1 24  PRO 24  10  10  PRO PRO L . n 
C 1 25  LYS 25  11  11  LYS LYS L . n 
C 1 26  LEU 26  12  12  LEU LEU L . n 
C 1 27  TYR 27  13  13  TYR TYR L . n 
C 1 28  VAL 28  14  14  VAL VAL L . n 
C 1 29  MET 29  15  15  MET MET L . n 
C 1 30  ASP 30  16  16  ASP ASP L . n 
C 1 31  ASN 31  17  17  ASN ASN L . n 
C 1 32  GLY 32  18  18  GLY GLY L . n 
C 1 33  ARG 33  19  19  ARG ARG L . n 
C 1 34  MET 34  20  20  MET MET L . n 
C 1 35  ARG 35  21  21  ARG ARG L . n 
C 1 36  MET 36  22  22  MET MET L . n 
C 1 37  ASP 37  23  23  ASP ASP L . n 
C 1 38  LYS 38  24  24  LYS LYS L . n 
C 1 39  ASN 39  25  25  ASN ASN L . n 
C 1 40  TRP 40  26  26  TRP TRP L . n 
C 1 41  MET 41  27  27  MET MET L . n 
C 1 42  ILE 42  28  28  ILE ILE L . n 
C 1 43  ALA 43  29  29  ALA ALA L . n 
C 1 44  MET 44  30  30  MET MET L . n 
C 1 45  HIS 45  31  31  HIS HIS L . n 
C 1 46  ASN 46  32  32  ASN ASN L . n 
C 1 47  PRO 47  33  33  PRO PRO L . n 
C 1 48  ALA 48  34  34  ALA ALA L . n 
C 1 49  THR 49  35  35  THR THR L . n 
C 1 50  ILE 50  36  36  ILE ILE L . n 
C 1 51  HIS 51  37  37  HIS HIS L . n 
C 1 52  ASN 52  38  38  ASN ASN L . n 
C 1 53  PRO 53  39  39  PRO PRO L . n 
C 1 54  ASN 54  40  40  ASN ASN L . n 
C 1 55  ALA 55  41  41  ALA ALA L . n 
C 1 56  GLN 56  42  42  GLN GLN L . n 
C 1 57  THR 57  43  43  THR THR L . n 
C 1 58  GLU 58  44  44  GLU GLU L . n 
C 1 59  PHE 59  45  45  PHE PHE L . n 
C 1 60  VAL 60  46  46  VAL VAL L . n 
C 1 61  GLU 61  47  47  GLU GLU L . n 
C 1 62  PHE 62  48  48  PHE PHE L . n 
C 1 63  PRO 63  49  49  PRO PRO L . n 
C 1 64  ILE 64  50  50  ILE ILE L . n 
C 1 65  TYR 65  51  51  TYR TYR L . n 
C 1 66  THR 66  52  52  THR THR L . n 
C 1 67  VAL 67  53  53  VAL VAL L . n 
C 1 68  LEU 68  54  54  LEU LEU L . n 
C 1 69  ILE 69  55  55  ILE ILE L . n 
C 1 70  ASP 70  56  56  ASP ASP L . n 
C 1 71  HIS 71  57  57  HIS HIS L . n 
C 1 72  PRO 72  58  58  PRO PRO L . n 
C 1 73  GLU 73  59  59  GLU GLU L . n 
C 1 74  GLY 74  60  60  GLY GLY L . n 
C 1 75  LYS 75  61  61  LYS LYS L . n 
C 1 76  ILE 76  62  62  ILE ILE L . n 
C 1 77  LEU 77  63  63  LEU LEU L . n 
C 1 78  PHE 78  64  64  PHE PHE L . n 
C 1 79  ASP 79  65  65  ASP ASP L . n 
C 1 80  THR 80  66  66  THR THR L . n 
C 1 81  SER 81  67  67  SER SER L . n 
C 1 82  CYS 82  68  68  CYS CYS L . n 
C 1 83  ASN 83  69  69  ASN ASN L . n 
C 1 84  PRO 84  70  70  PRO PRO L . n 
C 1 85  ASN 85  71  71  ASN ASN L . n 
C 1 86  SER 86  72  72  SER SER L . n 
C 1 87  MET 87  73  73  MET MET L . n 
C 1 88  GLY 88  74  74  GLY GLY L . n 
C 1 89  PRO 89  75  75  PRO PRO L . n 
C 1 90  GLN 90  76  76  GLN GLN L . n 
C 1 91  GLY 91  77  77  GLY GLY L . n 
C 1 92  ARG 92  78  78  ARG ARG L . n 
C 1 93  TRP 93  79  79  TRP TRP L . n 
C 1 94  ALA 94  80  80  ALA ALA L . n 
C 1 95  GLU 95  81  81  GLU GLU L . n 
C 1 96  SER 96  82  82  SER SER L . n 
C 1 97  THR 97  83  83  THR THR L . n 
C 1 98  GLN 98  84  84  GLN GLN L . n 
C 1 99  GLN 99  85  85  GLN GLN L . n 
C 1 100 MET 100 86  86  MET MET L . n 
C 1 101 PHE 101 87  87  PHE PHE L . n 
C 1 102 PRO 102 88  88  PRO PRO L . n 
C 1 103 TRP 103 89  89  TRP TRP L . n 
C 1 104 THR 104 90  90  THR THR L . n 
C 1 105 ALA 105 91  91  ALA ALA L . n 
C 1 106 THR 106 92  92  THR THR L . n 
C 1 107 GLU 107 93  93  GLU GLU L . n 
C 1 108 GLU 108 94  94  GLU GLU L . n 
C 1 109 CYS 109 95  95  CYS CYS L . n 
C 1 110 TYR 110 96  96  TYR TYR L . n 
C 1 111 LEU 111 97  97  LEU LEU L . n 
C 1 112 HIS 112 98  98  HIS HIS L . n 
C 1 113 ASN 113 99  99  ASN ASN L . n 
C 1 114 ARG 114 100 100 ARG ARG L . n 
C 1 115 LEU 115 101 101 LEU LEU L . n 
C 1 116 GLU 116 102 102 GLU GLU L . n 
C 1 117 GLN 117 103 103 GLN GLN L . n 
C 1 118 LEU 118 104 104 LEU LEU L . n 
C 1 119 LYS 119 105 105 LYS LYS L . n 
C 1 120 VAL 120 106 106 VAL VAL L . n 
C 1 121 ARG 121 107 107 ARG ARG L . n 
C 1 122 PRO 122 108 108 PRO PRO L . n 
C 1 123 GLU 123 109 109 GLU GLU L . n 
C 1 124 ASP 124 110 110 ASP ASP L . n 
C 1 125 ILE 125 111 111 ILE ILE L . n 
C 1 126 ARG 126 112 112 ARG ARG L . n 
C 1 127 TYR 127 113 113 TYR TYR L . n 
C 1 128 VAL 128 114 114 VAL VAL L . n 
C 1 129 VAL 129 115 115 VAL VAL L . n 
C 1 130 ALA 130 116 116 ALA ALA L . n 
C 1 131 SER 131 117 117 SER SER L . n 
C 1 132 HIS 132 118 118 HIS HIS L . n 
C 1 133 LEU 133 119 119 LEU LEU L . n 
C 1 134 HIS 134 120 120 HIS HIS L . n 
C 1 135 LEU 135 121 121 LEU LEU L . n 
C 1 136 ASP 136 122 122 ASP ASP L . n 
C 1 137 HIS 137 123 123 HIS HIS L . n 
C 1 138 ALA 138 124 124 ALA ALA L . n 
C 1 139 GLY 139 125 125 GLY GLY L . n 
C 1 140 CYS 140 126 126 CYS CYS L . n 
C 1 141 LEU 141 127 127 LEU LEU L . n 
C 1 142 GLU 142 128 128 GLU GLU L . n 
C 1 143 MET 143 129 129 MET MET L . n 
C 1 144 PHE 144 130 130 PHE PHE L . n 
C 1 145 THR 145 131 131 THR THR L . n 
C 1 146 ASN 146 132 132 ASN ASN L . n 
C 1 147 ALA 147 133 133 ALA ALA L . n 
C 1 148 THR 148 134 134 THR THR L . n 
C 1 149 ILE 149 135 135 ILE ILE L . n 
C 1 150 ILE 150 136 136 ILE ILE L . n 
C 1 151 VAL 151 137 137 VAL VAL L . n 
C 1 152 HIS 152 138 138 HIS HIS L . n 
C 1 153 GLU 153 139 139 GLU GLU L . n 
C 1 154 ASP 154 140 140 ASP ASP L . n 
C 1 155 GLU 155 141 141 GLU GLU L . n 
C 1 156 PHE 156 142 142 PHE PHE L . n 
C 1 157 ASN 157 143 143 ASN ASN L . n 
C 1 158 GLY 158 144 144 GLY GLY L . n 
C 1 159 ALA 159 145 145 ALA ALA L . n 
C 1 160 LEU 160 146 146 LEU LEU L . n 
C 1 161 GLN 161 147 147 GLN GLN L . n 
C 1 162 CYS 162 148 148 CYS CYS L . n 
C 1 163 TYR 163 149 149 TYR TYR L . n 
C 1 164 ALA 164 150 150 ALA ALA L . n 
C 1 165 ARG 165 151 151 ARG ARG L . n 
C 1 166 ASN 166 152 152 ASN ASN L . n 
C 1 167 GLN 167 153 153 GLN GLN L . n 
C 1 168 LYS 168 154 154 LYS LYS L . n 
C 1 169 GLU 169 155 155 GLU GLU L . n 
C 1 170 GLY 170 156 156 GLY GLY L . n 
C 1 171 ALA 171 157 157 ALA ALA L . n 
C 1 172 TYR 172 158 158 TYR TYR L . n 
C 1 173 ILE 173 159 159 ILE ILE L . n 
C 1 174 TRP 174 160 160 TRP TRP L . n 
C 1 175 ALA 175 161 161 ALA ALA L . n 
C 1 176 ASP 176 162 162 ASP ASP L . n 
C 1 177 ILE 177 163 163 ILE ILE L . n 
C 1 178 ASP 178 164 164 ASP ASP L . n 
C 1 179 ALA 179 165 165 ALA ALA L . n 
C 1 180 TRP 180 166 166 TRP TRP L . n 
C 1 181 ILE 181 167 167 ILE ILE L . n 
C 1 182 LYS 182 168 168 LYS LYS L . n 
C 1 183 ASN 183 169 169 ASN ASN L . n 
C 1 184 ASN 184 170 170 ASN ASN L . n 
C 1 185 LEU 185 171 171 LEU LEU L . n 
C 1 186 GLN 186 172 172 GLN GLN L . n 
C 1 187 TRP 187 173 173 TRP TRP L . n 
C 1 188 ARG 188 174 174 ARG ARG L . n 
C 1 189 THR 189 175 175 THR THR L . n 
C 1 190 VAL 190 176 176 VAL VAL L . n 
C 1 191 LYS 191 177 177 LYS LYS L . n 
C 1 192 ARG 192 178 178 ARG ARG L . n 
C 1 193 HIS 193 179 179 HIS HIS L . n 
C 1 194 GLU 194 180 180 GLU GLU L . n 
C 1 195 ASP 195 181 181 ASP ASP L . n 
C 1 196 ASN 196 182 182 ASN ASN L . n 
C 1 197 ILE 197 183 183 ILE ILE L . n 
C 1 198 LEU 198 184 184 LEU LEU L . n 
C 1 199 LEU 199 185 185 LEU LEU L . n 
C 1 200 ALA 200 186 186 ALA ALA L . n 
C 1 201 GLU 201 187 187 GLU GLU L . n 
C 1 202 GLY 202 188 188 GLY GLY L . n 
C 1 203 VAL 203 189 189 VAL VAL L . n 
C 1 204 LYS 204 190 190 LYS LYS L . n 
C 1 205 VAL 205 191 191 VAL VAL L . n 
C 1 206 LEU 206 192 192 LEU LEU L . n 
C 1 207 ASN 207 193 193 ASN ASN L . n 
C 1 208 PHE 208 194 194 PHE PHE L . n 
C 1 209 GLY 209 195 195 GLY GLY L . n 
C 1 210 SER 210 196 196 SER SER L . n 
C 1 211 GLY 211 197 197 GLY GLY L . n 
C 1 212 HIS 212 198 198 HIS HIS L . n 
C 1 213 ALA 213 199 199 ALA ALA L . n 
C 1 214 TRP 214 200 200 TRP TRP L . n 
C 1 215 GLY 215 201 201 GLY GLY L . n 
C 1 216 MET 216 202 202 MET MET L . n 
C 1 217 LEU 217 203 203 LEU LEU L . n 
C 1 218 GLY 218 204 204 GLY GLY L . n 
C 1 219 LEU 219 205 205 LEU LEU L . n 
C 1 220 HIS 220 206 206 HIS HIS L . n 
C 1 221 VAL 221 207 207 VAL VAL L . n 
C 1 222 GLU 222 208 208 GLU GLU L . n 
C 1 223 LEU 223 209 209 LEU LEU L . n 
C 1 224 PRO 224 210 210 PRO PRO L . n 
C 1 225 GLU 225 211 211 GLU GLU L . n 
C 1 226 THR 226 212 212 THR THR L . n 
C 1 227 GLY 227 213 213 GLY GLY L . n 
C 1 228 GLY 228 214 214 GLY GLY L . n 
C 1 229 ILE 229 215 215 ILE ILE L . n 
C 1 230 ILE 230 216 216 ILE ILE L . n 
C 1 231 LEU 231 217 217 LEU LEU L . n 
C 1 232 ALA 232 218 218 ALA ALA L . n 
C 1 233 SER 233 219 219 SER SER L . n 
C 1 234 ASP 234 220 220 ASP ASP L . n 
C 1 235 ALA 235 221 221 ALA ALA L . n 
C 1 236 ILE 236 222 222 ILE ILE L . n 
C 1 237 TYR 237 223 223 TYR TYR L . n 
C 1 238 THR 238 224 224 THR THR L . n 
C 1 239 ALA 239 225 225 ALA ALA L . n 
C 1 240 GLU 240 226 226 GLU GLU L . n 
C 1 241 SER 241 227 227 SER SER L . n 
C 1 242 TYR 242 228 228 TYR TYR L . n 
C 1 243 GLY 243 229 229 GLY GLY L . n 
C 1 244 PRO 244 230 230 PRO PRO L . n 
C 1 245 PRO 245 231 231 PRO PRO L . n 
C 1 246 ILE 246 232 232 ILE ILE L . n 
C 1 247 LYS 247 233 233 LYS LYS L . n 
C 1 248 PRO 248 234 234 PRO PRO L . n 
C 1 249 PRO 249 235 235 PRO PRO L . n 
C 1 250 GLY 250 236 236 GLY GLY L . n 
C 1 251 ILE 251 237 237 ILE ILE L . n 
C 1 252 ILE 252 238 238 ILE ILE L . n 
C 1 253 TYR 253 239 239 TYR TYR L . n 
C 1 254 ASP 254 240 240 ASP ASP L . n 
C 1 255 SER 255 241 241 SER SER L . n 
C 1 256 LEU 256 242 242 LEU LEU L . n 
C 1 257 GLY 257 243 243 GLY GLY L . n 
C 1 258 TYR 258 244 244 TYR TYR L . n 
C 1 259 MET 259 245 245 MET MET L . n 
C 1 260 ASN 260 246 246 ASN ASN L . n 
C 1 261 THR 261 247 247 THR THR L . n 
C 1 262 VAL 262 248 248 VAL VAL L . n 
C 1 263 GLU 263 249 249 GLU GLU L . n 
C 1 264 ARG 264 250 250 ARG ARG L . n 
C 1 265 ILE 265 251 251 ILE ILE L . n 
C 1 266 ARG 266 252 252 ARG ARG L . n 
C 1 267 ARG 267 253 253 ARG ARG L . n 
C 1 268 ILE 268 254 254 ILE ILE L . n 
C 1 269 ALA 269 255 255 ALA ALA L . n 
C 1 270 GLN 270 256 256 GLN GLN L . n 
C 1 271 GLU 271 257 257 GLU GLU L . n 
C 1 272 THR 272 258 258 THR THR L . n 
C 1 273 LYS 273 259 259 LYS LYS L . n 
C 1 274 SER 274 260 260 SER SER L . n 
C 1 275 GLN 275 261 261 GLN GLN L . n 
C 1 276 VAL 276 262 262 VAL VAL L . n 
C 1 277 TRP 277 263 263 TRP TRP L . n 
C 1 278 PHE 278 264 264 PHE PHE L . n 
C 1 279 GLY 279 265 265 GLY GLY L . n 
C 1 280 HIS 280 266 266 HIS HIS L . n 
C 1 281 ASP 281 267 267 ASP ASP L . n 
C 1 282 ALA 282 268 268 ALA ALA L . n 
C 1 283 GLU 283 269 269 GLU GLU L . n 
C 1 284 GLN 284 270 270 GLN GLN L . n 
C 1 285 PHE 285 271 271 PHE PHE L . n 
C 1 286 LYS 286 272 272 LYS LYS L . n 
C 1 287 LYS 287 273 273 LYS LYS L . n 
C 1 288 PHE 288 274 274 PHE PHE L . n 
C 1 289 ARG 289 275 275 ARG ARG L . n 
C 1 290 LYS 290 276 276 LYS LYS L . n 
C 1 291 SER 291 277 277 SER SER L . n 
C 1 292 THR 292 278 278 THR THR L . n 
C 1 293 GLU 293 279 279 GLU GLU L . n 
C 1 294 GLY 294 280 280 GLY GLY L . n 
C 1 295 TYR 295 281 281 TYR TYR L . n 
C 1 296 TYR 296 282 282 TYR TYR L . n 
C 1 297 GLU 297 283 283 GLU GLU L . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 FE ? ? FE ? ? 'SUBJECT OF INVESTIGATION' ? 
2 CO ? ? CO ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
D 2 A1AI3 1   301 301 A1AI3 DRG X . 
E 3 CO    1   302 301 CO    CO  X . 
F 4 SO4   1   303 303 SO4   SO4 X . 
G 4 SO4   1   304 304 SO4   SO4 X . 
H 5 FE    1   305 303 FE    FE  X . 
I 2 A1AI3 1   301 301 A1AI3 DRG F . 
J 3 CO    1   302 301 CO    CO  F . 
K 5 FE    1   303 302 FE    FE  F . 
L 4 SO4   1   304 303 SO4   SO4 F . 
M 4 SO4   1   305 304 SO4   SO4 F . 
N 2 A1AI3 1   301 301 A1AI3 DRG L . 
O 3 CO    1   302 301 CO    CO  L . 
P 5 FE    1   303 302 FE    FE  L . 
Q 4 SO4   1   304 303 SO4   SO4 L . 
R 6 HOH   1   401 91  HOH   HOH X . 
R 6 HOH   2   402 255 HOH   HOH X . 
R 6 HOH   3   403 292 HOH   HOH X . 
R 6 HOH   4   404 284 HOH   HOH X . 
R 6 HOH   5   405 348 HOH   HOH X . 
R 6 HOH   6   406 76  HOH   HOH X . 
R 6 HOH   7   407 60  HOH   HOH X . 
R 6 HOH   8   408 90  HOH   HOH X . 
R 6 HOH   9   409 112 HOH   HOH X . 
R 6 HOH   10  410 46  HOH   HOH X . 
R 6 HOH   11  411 36  HOH   HOH X . 
R 6 HOH   12  412 173 HOH   HOH X . 
R 6 HOH   13  413 233 HOH   HOH X . 
R 6 HOH   14  414 336 HOH   HOH X . 
R 6 HOH   15  415 102 HOH   HOH X . 
R 6 HOH   16  416 252 HOH   HOH X . 
R 6 HOH   17  417 117 HOH   HOH X . 
R 6 HOH   18  418 31  HOH   HOH X . 
R 6 HOH   19  419 29  HOH   HOH X . 
R 6 HOH   20  420 16  HOH   HOH X . 
R 6 HOH   21  421 178 HOH   HOH X . 
R 6 HOH   22  422 174 HOH   HOH X . 
R 6 HOH   23  423 202 HOH   HOH X . 
R 6 HOH   24  424 297 HOH   HOH X . 
R 6 HOH   25  425 149 HOH   HOH X . 
R 6 HOH   26  426 161 HOH   HOH X . 
R 6 HOH   27  427 134 HOH   HOH X . 
R 6 HOH   28  428 109 HOH   HOH X . 
R 6 HOH   29  429 279 HOH   HOH X . 
R 6 HOH   30  430 98  HOH   HOH X . 
R 6 HOH   31  431 193 HOH   HOH X . 
R 6 HOH   32  432 358 HOH   HOH X . 
R 6 HOH   33  433 93  HOH   HOH X . 
R 6 HOH   34  434 107 HOH   HOH X . 
R 6 HOH   35  435 87  HOH   HOH X . 
R 6 HOH   36  436 229 HOH   HOH X . 
R 6 HOH   37  437 290 HOH   HOH X . 
R 6 HOH   38  438 327 HOH   HOH X . 
R 6 HOH   39  439 27  HOH   HOH X . 
R 6 HOH   40  440 138 HOH   HOH X . 
R 6 HOH   41  441 221 HOH   HOH X . 
R 6 HOH   42  442 189 HOH   HOH X . 
R 6 HOH   43  443 146 HOH   HOH X . 
R 6 HOH   44  444 72  HOH   HOH X . 
R 6 HOH   45  445 303 HOH   HOH X . 
R 6 HOH   46  446 15  HOH   HOH X . 
R 6 HOH   47  447 155 HOH   HOH X . 
R 6 HOH   48  448 356 HOH   HOH X . 
R 6 HOH   49  449 116 HOH   HOH X . 
R 6 HOH   50  450 355 HOH   HOH X . 
R 6 HOH   51  451 94  HOH   HOH X . 
R 6 HOH   52  452 95  HOH   HOH X . 
R 6 HOH   53  453 80  HOH   HOH X . 
R 6 HOH   54  454 217 HOH   HOH X . 
R 6 HOH   55  455 67  HOH   HOH X . 
R 6 HOH   56  456 305 HOH   HOH X . 
R 6 HOH   57  457 24  HOH   HOH X . 
R 6 HOH   58  458 332 HOH   HOH X . 
R 6 HOH   59  459 9   HOH   HOH X . 
R 6 HOH   60  460 54  HOH   HOH X . 
R 6 HOH   61  461 51  HOH   HOH X . 
R 6 HOH   62  462 53  HOH   HOH X . 
R 6 HOH   63  463 295 HOH   HOH X . 
R 6 HOH   64  464 225 HOH   HOH X . 
R 6 HOH   65  465 145 HOH   HOH X . 
R 6 HOH   66  466 136 HOH   HOH X . 
R 6 HOH   67  467 160 HOH   HOH X . 
R 6 HOH   68  468 119 HOH   HOH X . 
R 6 HOH   69  469 344 HOH   HOH X . 
R 6 HOH   70  470 7   HOH   HOH X . 
R 6 HOH   71  471 11  HOH   HOH X . 
R 6 HOH   72  472 222 HOH   HOH X . 
R 6 HOH   73  473 33  HOH   HOH X . 
R 6 HOH   74  474 249 HOH   HOH X . 
R 6 HOH   75  475 206 HOH   HOH X . 
R 6 HOH   76  476 287 HOH   HOH X . 
R 6 HOH   77  477 58  HOH   HOH X . 
R 6 HOH   78  478 276 HOH   HOH X . 
R 6 HOH   79  479 183 HOH   HOH X . 
R 6 HOH   80  480 257 HOH   HOH X . 
R 6 HOH   81  481 293 HOH   HOH X . 
R 6 HOH   82  482 345 HOH   HOH X . 
R 6 HOH   83  483 294 HOH   HOH X . 
R 6 HOH   84  484 320 HOH   HOH X . 
R 6 HOH   85  485 171 HOH   HOH X . 
R 6 HOH   86  486 175 HOH   HOH X . 
R 6 HOH   87  487 22  HOH   HOH X . 
R 6 HOH   88  488 300 HOH   HOH X . 
R 6 HOH   89  489 346 HOH   HOH X . 
R 6 HOH   90  490 280 HOH   HOH X . 
R 6 HOH   91  491 196 HOH   HOH X . 
R 6 HOH   92  492 70  HOH   HOH X . 
R 6 HOH   93  493 135 HOH   HOH X . 
R 6 HOH   94  494 62  HOH   HOH X . 
R 6 HOH   95  495 253 HOH   HOH X . 
R 6 HOH   96  496 334 HOH   HOH X . 
R 6 HOH   97  497 340 HOH   HOH X . 
R 6 HOH   98  498 127 HOH   HOH X . 
R 6 HOH   99  499 213 HOH   HOH X . 
R 6 HOH   100 500 168 HOH   HOH X . 
R 6 HOH   101 501 273 HOH   HOH X . 
R 6 HOH   102 502 23  HOH   HOH X . 
R 6 HOH   103 503 240 HOH   HOH X . 
R 6 HOH   104 504 302 HOH   HOH X . 
R 6 HOH   105 505 122 HOH   HOH X . 
R 6 HOH   106 506 4   HOH   HOH X . 
R 6 HOH   107 507 266 HOH   HOH X . 
R 6 HOH   108 508 312 HOH   HOH X . 
R 6 HOH   109 509 333 HOH   HOH X . 
R 6 HOH   110 510 271 HOH   HOH X . 
R 6 HOH   111 511 298 HOH   HOH X . 
R 6 HOH   112 512 86  HOH   HOH X . 
R 6 HOH   113 513 132 HOH   HOH X . 
R 6 HOH   114 514 306 HOH   HOH X . 
R 6 HOH   115 515 263 HOH   HOH X . 
R 6 HOH   116 516 349 HOH   HOH X . 
R 6 HOH   117 517 326 HOH   HOH X . 
R 6 HOH   118 518 264 HOH   HOH X . 
R 6 HOH   119 519 238 HOH   HOH X . 
R 6 HOH   120 520 363 HOH   HOH X . 
R 6 HOH   121 521 209 HOH   HOH X . 
R 6 HOH   122 522 188 HOH   HOH X . 
R 6 HOH   123 523 144 HOH   HOH X . 
R 6 HOH   124 524 359 HOH   HOH X . 
R 6 HOH   125 525 235 HOH   HOH X . 
R 6 HOH   126 526 360 HOH   HOH X . 
R 6 HOH   127 527 314 HOH   HOH X . 
R 6 HOH   128 528 258 HOH   HOH X . 
R 6 HOH   129 529 362 HOH   HOH X . 
R 6 HOH   130 530 339 HOH   HOH X . 
R 6 HOH   131 531 210 HOH   HOH X . 
S 6 HOH   1   401 269 HOH   HOH F . 
S 6 HOH   2   402 230 HOH   HOH F . 
S 6 HOH   3   403 41  HOH   HOH F . 
S 6 HOH   4   404 296 HOH   HOH F . 
S 6 HOH   5   405 250 HOH   HOH F . 
S 6 HOH   6   406 44  HOH   HOH F . 
S 6 HOH   7   407 251 HOH   HOH F . 
S 6 HOH   8   408 59  HOH   HOH F . 
S 6 HOH   9   409 45  HOH   HOH F . 
S 6 HOH   10  410 101 HOH   HOH F . 
S 6 HOH   11  411 73  HOH   HOH F . 
S 6 HOH   12  412 71  HOH   HOH F . 
S 6 HOH   13  413 324 HOH   HOH F . 
S 6 HOH   14  414 317 HOH   HOH F . 
S 6 HOH   15  415 43  HOH   HOH F . 
S 6 HOH   16  416 111 HOH   HOH F . 
S 6 HOH   17  417 64  HOH   HOH F . 
S 6 HOH   18  418 150 HOH   HOH F . 
S 6 HOH   19  419 84  HOH   HOH F . 
S 6 HOH   20  420 68  HOH   HOH F . 
S 6 HOH   21  421 103 HOH   HOH F . 
S 6 HOH   22  422 128 HOH   HOH F . 
S 6 HOH   23  423 137 HOH   HOH F . 
S 6 HOH   24  424 163 HOH   HOH F . 
S 6 HOH   25  425 162 HOH   HOH F . 
S 6 HOH   26  426 50  HOH   HOH F . 
S 6 HOH   27  427 85  HOH   HOH F . 
S 6 HOH   28  428 66  HOH   HOH F . 
S 6 HOH   29  429 56  HOH   HOH F . 
S 6 HOH   30  430 227 HOH   HOH F . 
S 6 HOH   31  431 165 HOH   HOH F . 
S 6 HOH   32  432 299 HOH   HOH F . 
S 6 HOH   33  433 5   HOH   HOH F . 
S 6 HOH   34  434 179 HOH   HOH F . 
S 6 HOH   35  435 167 HOH   HOH F . 
S 6 HOH   36  436 114 HOH   HOH F . 
S 6 HOH   37  437 204 HOH   HOH F . 
S 6 HOH   38  438 354 HOH   HOH F . 
S 6 HOH   39  439 47  HOH   HOH F . 
S 6 HOH   40  440 115 HOH   HOH F . 
S 6 HOH   41  441 321 HOH   HOH F . 
S 6 HOH   42  442 275 HOH   HOH F . 
S 6 HOH   43  443 37  HOH   HOH F . 
S 6 HOH   44  444 335 HOH   HOH F . 
S 6 HOH   45  445 120 HOH   HOH F . 
S 6 HOH   46  446 351 HOH   HOH F . 
S 6 HOH   47  447 81  HOH   HOH F . 
S 6 HOH   48  448 212 HOH   HOH F . 
S 6 HOH   49  449 125 HOH   HOH F . 
S 6 HOH   50  450 108 HOH   HOH F . 
S 6 HOH   51  451 176 HOH   HOH F . 
S 6 HOH   52  452 140 HOH   HOH F . 
S 6 HOH   53  453 181 HOH   HOH F . 
S 6 HOH   54  454 20  HOH   HOH F . 
S 6 HOH   55  455 63  HOH   HOH F . 
S 6 HOH   56  456 106 HOH   HOH F . 
S 6 HOH   57  457 166 HOH   HOH F . 
S 6 HOH   58  458 226 HOH   HOH F . 
S 6 HOH   59  459 239 HOH   HOH F . 
S 6 HOH   60  460 352 HOH   HOH F . 
S 6 HOH   61  461 156 HOH   HOH F . 
S 6 HOH   62  462 99  HOH   HOH F . 
S 6 HOH   63  463 248 HOH   HOH F . 
S 6 HOH   64  464 267 HOH   HOH F . 
S 6 HOH   65  465 285 HOH   HOH F . 
S 6 HOH   66  466 105 HOH   HOH F . 
S 6 HOH   67  467 242 HOH   HOH F . 
S 6 HOH   68  468 124 HOH   HOH F . 
S 6 HOH   69  469 3   HOH   HOH F . 
S 6 HOH   70  470 28  HOH   HOH F . 
S 6 HOH   71  471 236 HOH   HOH F . 
S 6 HOH   72  472 278 HOH   HOH F . 
S 6 HOH   73  473 308 HOH   HOH F . 
S 6 HOH   74  474 152 HOH   HOH F . 
S 6 HOH   75  475 203 HOH   HOH F . 
S 6 HOH   76  476 19  HOH   HOH F . 
S 6 HOH   77  477 192 HOH   HOH F . 
S 6 HOH   78  478 30  HOH   HOH F . 
S 6 HOH   79  479 254 HOH   HOH F . 
S 6 HOH   80  480 231 HOH   HOH F . 
S 6 HOH   81  481 130 HOH   HOH F . 
S 6 HOH   82  482 1   HOH   HOH F . 
S 6 HOH   83  483 291 HOH   HOH F . 
S 6 HOH   84  484 34  HOH   HOH F . 
S 6 HOH   85  485 224 HOH   HOH F . 
S 6 HOH   86  486 184 HOH   HOH F . 
S 6 HOH   87  487 313 HOH   HOH F . 
S 6 HOH   88  488 48  HOH   HOH F . 
S 6 HOH   89  489 282 HOH   HOH F . 
S 6 HOH   90  490 147 HOH   HOH F . 
S 6 HOH   91  491 197 HOH   HOH F . 
S 6 HOH   92  492 139 HOH   HOH F . 
S 6 HOH   93  493 241 HOH   HOH F . 
S 6 HOH   94  494 223 HOH   HOH F . 
S 6 HOH   95  495 40  HOH   HOH F . 
S 6 HOH   96  496 32  HOH   HOH F . 
S 6 HOH   97  497 307 HOH   HOH F . 
S 6 HOH   98  498 169 HOH   HOH F . 
S 6 HOH   99  499 304 HOH   HOH F . 
S 6 HOH   100 500 25  HOH   HOH F . 
S 6 HOH   101 501 270 HOH   HOH F . 
S 6 HOH   102 502 13  HOH   HOH F . 
S 6 HOH   103 503 338 HOH   HOH F . 
S 6 HOH   104 504 281 HOH   HOH F . 
S 6 HOH   105 505 247 HOH   HOH F . 
S 6 HOH   106 506 311 HOH   HOH F . 
S 6 HOH   107 507 353 HOH   HOH F . 
S 6 HOH   108 508 77  HOH   HOH F . 
S 6 HOH   109 509 268 HOH   HOH F . 
S 6 HOH   110 510 289 HOH   HOH F . 
S 6 HOH   111 511 283 HOH   HOH F . 
S 6 HOH   112 512 286 HOH   HOH F . 
S 6 HOH   113 513 243 HOH   HOH F . 
S 6 HOH   114 514 154 HOH   HOH F . 
S 6 HOH   115 515 219 HOH   HOH F . 
S 6 HOH   116 516 361 HOH   HOH F . 
S 6 HOH   117 517 246 HOH   HOH F . 
T 6 HOH   1   401 318 HOH   HOH L . 
T 6 HOH   2   402 309 HOH   HOH L . 
T 6 HOH   3   403 310 HOH   HOH L . 
T 6 HOH   4   404 245 HOH   HOH L . 
T 6 HOH   5   405 78  HOH   HOH L . 
T 6 HOH   6   406 316 HOH   HOH L . 
T 6 HOH   7   407 201 HOH   HOH L . 
T 6 HOH   8   408 55  HOH   HOH L . 
T 6 HOH   9   409 234 HOH   HOH L . 
T 6 HOH   10  410 180 HOH   HOH L . 
T 6 HOH   11  411 237 HOH   HOH L . 
T 6 HOH   12  412 42  HOH   HOH L . 
T 6 HOH   13  413 118 HOH   HOH L . 
T 6 HOH   14  414 198 HOH   HOH L . 
T 6 HOH   15  415 205 HOH   HOH L . 
T 6 HOH   16  416 153 HOH   HOH L . 
T 6 HOH   17  417 214 HOH   HOH L . 
T 6 HOH   18  418 92  HOH   HOH L . 
T 6 HOH   19  419 75  HOH   HOH L . 
T 6 HOH   20  420 89  HOH   HOH L . 
T 6 HOH   21  421 26  HOH   HOH L . 
T 6 HOH   22  422 96  HOH   HOH L . 
T 6 HOH   23  423 343 HOH   HOH L . 
T 6 HOH   24  424 129 HOH   HOH L . 
T 6 HOH   25  425 110 HOH   HOH L . 
T 6 HOH   26  426 82  HOH   HOH L . 
T 6 HOH   27  427 49  HOH   HOH L . 
T 6 HOH   28  428 195 HOH   HOH L . 
T 6 HOH   29  429 170 HOH   HOH L . 
T 6 HOH   30  430 199 HOH   HOH L . 
T 6 HOH   31  431 157 HOH   HOH L . 
T 6 HOH   32  432 337 HOH   HOH L . 
T 6 HOH   33  433 12  HOH   HOH L . 
T 6 HOH   34  434 185 HOH   HOH L . 
T 6 HOH   35  435 69  HOH   HOH L . 
T 6 HOH   36  436 220 HOH   HOH L . 
T 6 HOH   37  437 88  HOH   HOH L . 
T 6 HOH   38  438 97  HOH   HOH L . 
T 6 HOH   39  439 104 HOH   HOH L . 
T 6 HOH   40  440 341 HOH   HOH L . 
T 6 HOH   41  441 74  HOH   HOH L . 
T 6 HOH   42  442 277 HOH   HOH L . 
T 6 HOH   43  443 52  HOH   HOH L . 
T 6 HOH   44  444 17  HOH   HOH L . 
T 6 HOH   45  445 141 HOH   HOH L . 
T 6 HOH   46  446 133 HOH   HOH L . 
T 6 HOH   47  447 18  HOH   HOH L . 
T 6 HOH   48  448 142 HOH   HOH L . 
T 6 HOH   49  449 177 HOH   HOH L . 
T 6 HOH   50  450 83  HOH   HOH L . 
T 6 HOH   51  451 39  HOH   HOH L . 
T 6 HOH   52  452 216 HOH   HOH L . 
T 6 HOH   53  453 21  HOH   HOH L . 
T 6 HOH   54  454 190 HOH   HOH L . 
T 6 HOH   55  455 319 HOH   HOH L . 
T 6 HOH   56  456 200 HOH   HOH L . 
T 6 HOH   57  457 331 HOH   HOH L . 
T 6 HOH   58  458 315 HOH   HOH L . 
T 6 HOH   59  459 6   HOH   HOH L . 
T 6 HOH   60  460 131 HOH   HOH L . 
T 6 HOH   61  461 65  HOH   HOH L . 
T 6 HOH   62  462 288 HOH   HOH L . 
T 6 HOH   63  463 207 HOH   HOH L . 
T 6 HOH   64  464 38  HOH   HOH L . 
T 6 HOH   65  465 187 HOH   HOH L . 
T 6 HOH   66  466 342 HOH   HOH L . 
T 6 HOH   67  467 121 HOH   HOH L . 
T 6 HOH   68  468 158 HOH   HOH L . 
T 6 HOH   69  469 164 HOH   HOH L . 
T 6 HOH   70  470 143 HOH   HOH L . 
T 6 HOH   71  471 301 HOH   HOH L . 
T 6 HOH   72  472 244 HOH   HOH L . 
T 6 HOH   73  473 35  HOH   HOH L . 
T 6 HOH   74  474 14  HOH   HOH L . 
T 6 HOH   75  475 123 HOH   HOH L . 
T 6 HOH   76  476 113 HOH   HOH L . 
T 6 HOH   77  477 215 HOH   HOH L . 
T 6 HOH   78  478 79  HOH   HOH L . 
T 6 HOH   79  479 330 HOH   HOH L . 
T 6 HOH   80  480 151 HOH   HOH L . 
T 6 HOH   81  481 186 HOH   HOH L . 
T 6 HOH   82  482 100 HOH   HOH L . 
T 6 HOH   83  483 8   HOH   HOH L . 
T 6 HOH   84  484 218 HOH   HOH L . 
T 6 HOH   85  485 211 HOH   HOH L . 
T 6 HOH   86  486 347 HOH   HOH L . 
T 6 HOH   87  487 172 HOH   HOH L . 
T 6 HOH   88  488 328 HOH   HOH L . 
T 6 HOH   89  489 126 HOH   HOH L . 
T 6 HOH   90  490 272 HOH   HOH L . 
T 6 HOH   91  491 57  HOH   HOH L . 
T 6 HOH   92  492 182 HOH   HOH L . 
T 6 HOH   93  493 228 HOH   HOH L . 
T 6 HOH   94  494 10  HOH   HOH L . 
T 6 HOH   95  495 322 HOH   HOH L . 
T 6 HOH   96  496 148 HOH   HOH L . 
T 6 HOH   97  497 208 HOH   HOH L . 
T 6 HOH   98  498 357 HOH   HOH L . 
T 6 HOH   99  499 2   HOH   HOH L . 
T 6 HOH   100 500 329 HOH   HOH L . 
T 6 HOH   101 501 232 HOH   HOH L . 
T 6 HOH   102 502 191 HOH   HOH L . 
T 6 HOH   103 503 61  HOH   HOH L . 
T 6 HOH   104 504 159 HOH   HOH L . 
T 6 HOH   105 505 325 HOH   HOH L . 
T 6 HOH   106 506 350 HOH   HOH L . 
T 6 HOH   107 507 265 HOH   HOH L . 
T 6 HOH   108 508 262 HOH   HOH L . 
T 6 HOH   109 509 274 HOH   HOH L . 
T 6 HOH   110 510 323 HOH   HOH L . 
T 6 HOH   111 511 259 HOH   HOH L . 
T 6 HOH   112 512 260 HOH   HOH L . 
T 6 HOH   113 513 261 HOH   HOH L . 
T 6 HOH   114 514 256 HOH   HOH L . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC ? ? ? 5.8.0266 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? XSCALE ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? MOLREP ? ? ? .        4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   116.35 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9B2O 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     161.360 
_cell.length_a_esd                 ? 
_cell.length_b                     109.810 
_cell.length_b_esd                 ? 
_cell.length_c                     97.370 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        12 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9B2O 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                5 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'C 1 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9B2O 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.75 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          67.18 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '1.0 - 1.25 M ammonium sulfate and 0.1 M sodium acetate pH 4.0 - 5.5' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            292 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2017-08-23 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.03321 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'APS BEAMLINE 23-ID-D' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.03321 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   23-ID-D 
_diffrn_source.pdbx_synchrotron_site       APS 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9B2O 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.85 
_reflns.d_resolution_low                               74.13 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     124206 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           95.8 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                4.62 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          14.19 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.999 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.85 
_reflns_shell.d_res_low                                     1.95 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             17767 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.927 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            0.00 
_refine.aniso_B[1][2]                            -0.00 
_refine.aniso_B[1][3]                            -0.01 
_refine.aniso_B[2][2]                            -0.00 
_refine.aniso_B[2][3]                            -0.00 
_refine.aniso_B[3][3]                            0.01 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               41.042 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.969 
_refine.correlation_coeff_Fo_to_Fc_free          0.959 
_refine.details                                  'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9B2O 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.85 
_refine.ls_d_res_low                             74.13 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     117995 
_refine.ls_number_reflns_R_free                  6211 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    95.93 
_refine.ls_percent_reflns_R_free                 5.0 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.18814 
_refine.ls_R_factor_R_free                       0.21475 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.18674 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    MASK 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'MAXIMUM LIKELIHOOD' 
_refine.pdbx_R_Free_selection_details            RANDOM 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.101 
_refine.pdbx_overall_ESU_R_Free                  0.101 
_refine.pdbx_solvent_vdw_probe_radii             1.20 
_refine.pdbx_solvent_ion_probe_radii             0.80 
_refine.pdbx_solvent_shrinkage_radii             0.80 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             3.134 
_refine.overall_SU_ML                            0.087 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         1 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.85 
_refine_hist.d_res_low                        74.13 
_refine_hist.number_atoms_solvent             362 
_refine_hist.number_atoms_total               7155 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        6711 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         82 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.012  0.013  6968  ? r_bond_refined_d             ? ? 
'X-RAY DIFFRACTION' ? 0.004  0.017  6366  ? r_bond_other_d               ? ? 
'X-RAY DIFFRACTION' ? 1.702  1.647  9450  ? r_angle_refined_deg          ? ? 
'X-RAY DIFFRACTION' ? 1.503  1.595  14661 ? r_angle_other_deg            ? ? 
'X-RAY DIFFRACTION' ? 7.079  5.000  825   ? r_dihedral_angle_1_deg       ? ? 
'X-RAY DIFFRACTION' ? 36.256 22.576 396   ? r_dihedral_angle_2_deg       ? ? 
'X-RAY DIFFRACTION' ? 14.483 15.000 1143  ? r_dihedral_angle_3_deg       ? ? 
'X-RAY DIFFRACTION' ? 19.585 15.000 42    ? r_dihedral_angle_4_deg       ? ? 
'X-RAY DIFFRACTION' ? 0.081  0.200  879   ? r_chiral_restr               ? ? 
'X-RAY DIFFRACTION' ? 0.010  0.020  7956  ? r_gen_planes_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.020  1668  ? r_gen_planes_other           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbd_refined                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbd_other                  ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbtor_refined              ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbtor_other                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_xyhbond_nbd_refined        ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_xyhbond_nbd_other          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_metal_ion_refined          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_metal_ion_other            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_vdw_refined       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_vdw_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_hbond_refined     ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_hbond_other       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_metal_ion_refined ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_metal_ion_other   ? ? 
'X-RAY DIFFRACTION' ? 3.421  3.965  3318  ? r_mcbond_it                  ? ? 
'X-RAY DIFFRACTION' ? 3.400  3.964  3317  ? r_mcbond_other               ? ? 
'X-RAY DIFFRACTION' ? 4.160  5.926  4137  ? r_mcangle_it                 ? ? 
'X-RAY DIFFRACTION' ? 4.160  5.927  4138  ? r_mcangle_other              ? ? 
'X-RAY DIFFRACTION' ? 5.549  4.625  3650  ? r_scbond_it                  ? ? 
'X-RAY DIFFRACTION' ? 5.527  4.621  3646  ? r_scbond_other               ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_scangle_it                 ? ? 
'X-RAY DIFFRACTION' ? 7.875  6.690  5308  ? r_scangle_other              ? ? 
'X-RAY DIFFRACTION' ? 9.000  45.451 7629  ? r_long_range_B_refined       ? ? 
'X-RAY DIFFRACTION' ? 9.013  45.344 7584  ? r_long_range_B_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_rigid_bond_restr           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_sphericity_free            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_sphericity_bonded          ? ? 
# 
_refine_ls_shell.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_ls_shell.d_res_high                       1.850 
_refine_ls_shell.d_res_low                        1.898 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.number_reflns_obs                ? 
_refine_ls_shell.number_reflns_R_free             448 
_refine_ls_shell.number_reflns_R_work             8510 
_refine_ls_shell.percent_reflns_obs               94.18 
_refine_ls_shell.percent_reflns_R_free            ? 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.R_factor_obs                     ? 
_refine_ls_shell.R_factor_R_free_error            ? 
_refine_ls_shell.R_factor_R_work                  0.332 
_refine_ls_shell.redundancy_reflns_all            ? 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.wR_factor_all                    ? 
_refine_ls_shell.wR_factor_obs                    ? 
_refine_ls_shell.wR_factor_R_free                 ? 
_refine_ls_shell.wR_factor_R_work                 ? 
_refine_ls_shell.pdbx_R_complete                  ? 
_refine_ls_shell.pdbx_total_number_of_bins_used   20 
_refine_ls_shell.pdbx_phase_error                 ? 
_refine_ls_shell.pdbx_fsc_work                    ? 
_refine_ls_shell.pdbx_fsc_free                    ? 
_refine_ls_shell.R_factor_R_free                  0.347 
# 
_struct.entry_id                     9B2O 
_struct.title                        
'Structure of the quorum quenching lactonase GcL bound to the hydrolysis product of N-octanoyl-L-homoserine lactone' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9B2O 
_struct_keywords.text            'quorum sensing, quorum quenching, lactonase, metalloenzyme, HYDROLASE, HYDROLASE-PRODUCT complex' 
_struct_keywords.pdbx_keywords   HYDROLASE/PRODUCT 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 2 ? 
E N N 3 ? 
F N N 4 ? 
G N N 4 ? 
H N N 5 ? 
I N N 2 ? 
J N N 3 ? 
K N N 5 ? 
L N N 4 ? 
M N N 4 ? 
N N N 2 ? 
O N N 3 ? 
P N N 5 ? 
Q N N 4 ? 
R N N 6 ? 
S N N 6 ? 
T N N 6 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A023DFE8_9BACI 
_struct_ref.pdbx_db_accession          A0A023DFE8 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MANVIKARPKLYVMDNGRMRMDKNWMIAMHNPATIHNPNAQTEFVEFPIYTVLIDHPEGKILFDTSCNPNSMGPQGRWAE
STQQMFPWTATEECYLHNRLEQLKVRPEDIRYVVASHLHLDHAGCLEMFTNATIIVHEDEFNGALQCYARNQKEGAYIWA
DIDAWIKNNLQWRTVKRHEDNILLAEGVKVLNFGSGHAWGMLGLHVELPETGGIILASDAIYTAESYGPPIKPPGIIYDS
LGYMNTVERIRRIAQETKSQVWFGHDAEQFKKFRKSTEGYYE
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9B2O X 16 ? 297 ? A0A023DFE8 1 ? 282 ? 2 283 
2 1 9B2O F 16 ? 297 ? A0A023DFE8 1 ? 282 ? 2 283 
3 1 9B2O L 16 ? 297 ? A0A023DFE8 1 ? 282 ? 2 283 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9B2O TRP X 1  ? UNP A0A023DFE8 ? ? 'expression tag' -13 1  
1 9B2O SER X 2  ? UNP A0A023DFE8 ? ? 'expression tag' -12 2  
1 9B2O HIS X 3  ? UNP A0A023DFE8 ? ? 'expression tag' -11 3  
1 9B2O PRO X 4  ? UNP A0A023DFE8 ? ? 'expression tag' -10 4  
1 9B2O GLN X 5  ? UNP A0A023DFE8 ? ? 'expression tag' -9  5  
1 9B2O PHE X 6  ? UNP A0A023DFE8 ? ? 'expression tag' -8  6  
1 9B2O GLU X 7  ? UNP A0A023DFE8 ? ? 'expression tag' -7  7  
1 9B2O LYS X 8  ? UNP A0A023DFE8 ? ? 'expression tag' -6  8  
1 9B2O GLU X 9  ? UNP A0A023DFE8 ? ? 'expression tag' -5  9  
1 9B2O ASN X 10 ? UNP A0A023DFE8 ? ? 'expression tag' -4  10 
1 9B2O LEU X 11 ? UNP A0A023DFE8 ? ? 'expression tag' -3  11 
1 9B2O TYR X 12 ? UNP A0A023DFE8 ? ? 'expression tag' -2  12 
1 9B2O PHE X 13 ? UNP A0A023DFE8 ? ? 'expression tag' -1  13 
1 9B2O GLN X 14 ? UNP A0A023DFE8 ? ? 'expression tag' 0   14 
1 9B2O SER X 15 ? UNP A0A023DFE8 ? ? 'expression tag' 1   15 
2 9B2O TRP F 1  ? UNP A0A023DFE8 ? ? 'expression tag' -13 16 
2 9B2O SER F 2  ? UNP A0A023DFE8 ? ? 'expression tag' -12 17 
2 9B2O HIS F 3  ? UNP A0A023DFE8 ? ? 'expression tag' -11 18 
2 9B2O PRO F 4  ? UNP A0A023DFE8 ? ? 'expression tag' -10 19 
2 9B2O GLN F 5  ? UNP A0A023DFE8 ? ? 'expression tag' -9  20 
2 9B2O PHE F 6  ? UNP A0A023DFE8 ? ? 'expression tag' -8  21 
2 9B2O GLU F 7  ? UNP A0A023DFE8 ? ? 'expression tag' -7  22 
2 9B2O LYS F 8  ? UNP A0A023DFE8 ? ? 'expression tag' -6  23 
2 9B2O GLU F 9  ? UNP A0A023DFE8 ? ? 'expression tag' -5  24 
2 9B2O ASN F 10 ? UNP A0A023DFE8 ? ? 'expression tag' -4  25 
2 9B2O LEU F 11 ? UNP A0A023DFE8 ? ? 'expression tag' -3  26 
2 9B2O TYR F 12 ? UNP A0A023DFE8 ? ? 'expression tag' -2  27 
2 9B2O PHE F 13 ? UNP A0A023DFE8 ? ? 'expression tag' -1  28 
2 9B2O GLN F 14 ? UNP A0A023DFE8 ? ? 'expression tag' 0   29 
2 9B2O SER F 15 ? UNP A0A023DFE8 ? ? 'expression tag' 1   30 
3 9B2O TRP L 1  ? UNP A0A023DFE8 ? ? 'expression tag' -13 31 
3 9B2O SER L 2  ? UNP A0A023DFE8 ? ? 'expression tag' -12 32 
3 9B2O HIS L 3  ? UNP A0A023DFE8 ? ? 'expression tag' -11 33 
3 9B2O PRO L 4  ? UNP A0A023DFE8 ? ? 'expression tag' -10 34 
3 9B2O GLN L 5  ? UNP A0A023DFE8 ? ? 'expression tag' -9  35 
3 9B2O PHE L 6  ? UNP A0A023DFE8 ? ? 'expression tag' -8  36 
3 9B2O GLU L 7  ? UNP A0A023DFE8 ? ? 'expression tag' -7  37 
3 9B2O LYS L 8  ? UNP A0A023DFE8 ? ? 'expression tag' -6  38 
3 9B2O GLU L 9  ? UNP A0A023DFE8 ? ? 'expression tag' -5  39 
3 9B2O ASN L 10 ? UNP A0A023DFE8 ? ? 'expression tag' -4  40 
3 9B2O LEU L 11 ? UNP A0A023DFE8 ? ? 'expression tag' -3  41 
3 9B2O TYR L 12 ? UNP A0A023DFE8 ? ? 'expression tag' -2  42 
3 9B2O PHE L 13 ? UNP A0A023DFE8 ? ? 'expression tag' -1  43 
3 9B2O GLN L 14 ? UNP A0A023DFE8 ? ? 'expression tag' 0   44 
3 9B2O SER L 15 ? UNP A0A023DFE8 ? ? 'expression tag' 1   45 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_and_software_defined_assembly PISA dimeric 2 
2 author_and_software_defined_assembly PISA dimeric 2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 5010  ? 
1 MORE         -127  ? 
1 'SSA (A^2)'  23070 ? 
2 'ABSA (A^2)' 4760  ? 
2 MORE         -107  ? 
2 'SSA (A^2)'  23080 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1   A,B,D,E,F,G,H,I,J,K,L,M,R,S 
2 1,2 C,N,O,P,Q,T                 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
1 'identity operation'         1_555 x,y,z   1.0000000000  0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 
0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000  0.0000000000 
2 'crystal symmetry operation' 2_555 -x,y,-z -1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 
0.0000000000 0.0000000000 0.0000000000 0.0000000000 -1.0000000000 0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 LYS A 38  ? ILE A 42  ? LYS X 24  ILE X 28  1 ? 5  
HELX_P HELX_P2  AA2 ALA A 94  ? PHE A 101 ? ALA X 80  PHE X 87  1 ? 8  
HELX_P HELX_P3  AA3 THR A 106 ? CYS A 109 ? THR X 92  CYS X 95  5 ? 4  
HELX_P HELX_P4  AA4 TYR A 110 ? LEU A 118 ? TYR X 96  LEU X 104 1 ? 9  
HELX_P HELX_P5  AA5 ARG A 121 ? GLU A 123 ? ARG X 107 GLU X 109 5 ? 3  
HELX_P HELX_P6  AA6 CYS A 140 ? PHE A 144 ? CYS X 126 PHE X 130 5 ? 5  
HELX_P HELX_P7  AA7 GLU A 153 ? ARG A 165 ? GLU X 139 ARG X 151 1 ? 13 
HELX_P HELX_P8  AA8 ILE A 173 ? ASN A 183 ? ILE X 159 ASN X 169 1 ? 11 
HELX_P HELX_P9  AA9 ASP A 234 ? ILE A 236 ? ASP X 220 ILE X 222 5 ? 3  
HELX_P HELX_P10 AB1 THR A 238 ? GLY A 243 ? THR X 224 GLY X 229 1 ? 6  
HELX_P HELX_P11 AB2 ASP A 254 ? LYS A 273 ? ASP X 240 LYS X 259 1 ? 20 
HELX_P HELX_P12 AB3 ASP A 281 ? PHE A 288 ? ASP X 267 PHE X 274 1 ? 8  
HELX_P HELX_P13 AB4 LYS B 38  ? ILE B 42  ? LYS F 24  ILE F 28  1 ? 5  
HELX_P HELX_P14 AB5 ALA B 94  ? PHE B 101 ? ALA F 80  PHE F 87  1 ? 8  
HELX_P HELX_P15 AB6 THR B 106 ? CYS B 109 ? THR F 92  CYS F 95  5 ? 4  
HELX_P HELX_P16 AB7 TYR B 110 ? LEU B 118 ? TYR F 96  LEU F 104 1 ? 9  
HELX_P HELX_P17 AB8 ARG B 121 ? GLU B 123 ? ARG F 107 GLU F 109 5 ? 3  
HELX_P HELX_P18 AB9 CYS B 140 ? PHE B 144 ? CYS F 126 PHE F 130 5 ? 5  
HELX_P HELX_P19 AC1 GLU B 153 ? ARG B 165 ? GLU F 139 ARG F 151 1 ? 13 
HELX_P HELX_P20 AC2 ILE B 173 ? ASN B 183 ? ILE F 159 ASN F 169 1 ? 11 
HELX_P HELX_P21 AC3 ASP B 234 ? ILE B 236 ? ASP F 220 ILE F 222 5 ? 3  
HELX_P HELX_P22 AC4 THR B 238 ? GLY B 243 ? THR F 224 GLY F 229 1 ? 6  
HELX_P HELX_P23 AC5 ASP B 254 ? LYS B 273 ? ASP F 240 LYS F 259 1 ? 20 
HELX_P HELX_P24 AC6 ASP B 281 ? PHE B 288 ? ASP F 267 PHE F 274 1 ? 8  
HELX_P HELX_P25 AC7 LYS C 38  ? ILE C 42  ? LYS L 24  ILE L 28  1 ? 5  
HELX_P HELX_P26 AC8 ALA C 94  ? PHE C 101 ? ALA L 80  PHE L 87  1 ? 8  
HELX_P HELX_P27 AC9 THR C 106 ? CYS C 109 ? THR L 92  CYS L 95  5 ? 4  
HELX_P HELX_P28 AD1 TYR C 110 ? GLN C 117 ? TYR L 96  GLN L 103 1 ? 8  
HELX_P HELX_P29 AD2 ARG C 121 ? GLU C 123 ? ARG L 107 GLU L 109 5 ? 3  
HELX_P HELX_P30 AD3 CYS C 140 ? PHE C 144 ? CYS L 126 PHE L 130 5 ? 5  
HELX_P HELX_P31 AD4 GLU C 153 ? ARG C 165 ? GLU L 139 ARG L 151 1 ? 13 
HELX_P HELX_P32 AD5 ILE C 173 ? ASN C 183 ? ILE L 159 ASN L 169 1 ? 11 
HELX_P HELX_P33 AD6 ASP C 234 ? ILE C 236 ? ASP L 220 ILE L 222 5 ? 3  
HELX_P HELX_P34 AD7 THR C 238 ? GLY C 243 ? THR L 224 GLY L 229 1 ? 6  
HELX_P HELX_P35 AD8 ASP C 254 ? LYS C 273 ? ASP L 240 LYS L 259 1 ? 20 
HELX_P HELX_P36 AD9 ASP C 281 ? PHE C 288 ? ASP L 267 PHE L 274 1 ? 8  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1  metalc ? ? A HIS   132 NE2 ? ? ? 1_555 E CO . CO ? ? X HIS   118 X CO 302 1_555 ? ? ? ? ? ? ? 2.026 ? ? 
metalc2  metalc ? ? A HIS   134 ND1 ? ? ? 1_555 E CO . CO ? ? X HIS   120 X CO 302 1_555 ? ? ? ? ? ? ? 2.046 ? ? 
metalc3  metalc ? ? A ASP   136 OD2 ? ? ? 1_555 H FE . FE ? ? X ASP   122 X FE 305 1_555 ? ? ? ? ? ? ? 2.125 ? ? 
metalc4  metalc ? ? A HIS   137 NE2 ? ? ? 1_555 H FE . FE ? ? X HIS   123 X FE 305 1_555 ? ? ? ? ? ? ? 2.145 ? ? 
metalc5  metalc ? ? A HIS   212 NE2 ? ? ? 1_555 E CO . CO ? ? X HIS   198 X CO 302 1_555 ? ? ? ? ? ? ? 2.117 ? ? 
metalc6  metalc ? ? A ASP   234 OD2 ? ? ? 1_555 E CO . CO ? ? X ASP   220 X CO 302 1_555 ? ? ? ? ? ? ? 2.407 ? ? 
metalc7  metalc ? ? A ASP   234 OD2 ? ? ? 1_555 H FE . FE ? ? X ASP   220 X FE 305 1_555 ? ? ? ? ? ? ? 2.206 ? ? 
metalc8  metalc ? ? A HIS   280 NE2 ? ? ? 1_555 H FE . FE ? ? X HIS   266 X FE 305 1_555 ? ? ? ? ? ? ? 2.107 ? ? 
metalc9  metalc ? ? D A1AI3 .   OXT ? ? ? 1_555 E CO . CO ? ? X A1AI3 301 X CO 302 1_555 ? ? ? ? ? ? ? 2.283 ? ? 
metalc10 metalc ? ? D A1AI3 .   O   ? ? ? 1_555 E CO . CO ? ? X A1AI3 301 X CO 302 1_555 ? ? ? ? ? ? ? 2.581 ? ? 
metalc11 metalc ? ? D A1AI3 .   OXT ? ? ? 1_555 H FE . FE ? ? X A1AI3 301 X FE 305 1_555 ? ? ? ? ? ? ? 2.644 ? ? 
metalc12 metalc ? ? D A1AI3 .   OAQ ? ? ? 1_555 H FE . FE ? ? X A1AI3 301 X FE 305 1_555 ? ? ? ? ? ? ? 2.449 ? ? 
metalc13 metalc ? ? B HIS   132 NE2 ? ? ? 1_555 J CO . CO ? ? F HIS   118 F CO 302 1_555 ? ? ? ? ? ? ? 2.046 ? ? 
metalc14 metalc ? ? B HIS   134 ND1 ? ? ? 1_555 J CO . CO ? ? F HIS   120 F CO 302 1_555 ? ? ? ? ? ? ? 2.026 ? ? 
metalc15 metalc ? ? B ASP   136 OD2 ? ? ? 1_555 K FE . FE ? ? F ASP   122 F FE 303 1_555 ? ? ? ? ? ? ? 2.111 ? ? 
metalc16 metalc ? ? B HIS   137 NE2 ? ? ? 1_555 K FE . FE ? ? F HIS   123 F FE 303 1_555 ? ? ? ? ? ? ? 2.201 ? ? 
metalc17 metalc ? ? B HIS   212 NE2 ? ? ? 1_555 J CO . CO ? ? F HIS   198 F CO 302 1_555 ? ? ? ? ? ? ? 2.097 ? ? 
metalc18 metalc ? ? B ASP   234 OD2 ? ? ? 1_555 J CO . CO ? ? F ASP   220 F CO 302 1_555 ? ? ? ? ? ? ? 2.435 ? ? 
metalc19 metalc ? ? B ASP   234 OD2 ? ? ? 1_555 K FE . FE ? ? F ASP   220 F FE 303 1_555 ? ? ? ? ? ? ? 2.207 ? ? 
metalc20 metalc ? ? B HIS   280 NE2 ? ? ? 1_555 K FE . FE ? ? F HIS   266 F FE 303 1_555 ? ? ? ? ? ? ? 2.220 ? ? 
metalc21 metalc ? ? I A1AI3 .   OXT ? ? ? 1_555 J CO . CO ? ? F A1AI3 301 F CO 302 1_555 ? ? ? ? ? ? ? 2.669 ? ? 
metalc22 metalc ? ? I A1AI3 .   O   ? ? ? 1_555 J CO . CO ? ? F A1AI3 301 F CO 302 1_555 ? ? ? ? ? ? ? 2.058 ? ? 
metalc23 metalc ? ? I A1AI3 .   O   ? ? ? 1_555 K FE . FE ? ? F A1AI3 301 F FE 303 1_555 ? ? ? ? ? ? ? 2.624 ? ? 
metalc24 metalc ? ? I A1AI3 .   OAQ ? ? ? 1_555 K FE . FE ? ? F A1AI3 301 F FE 303 1_555 ? ? ? ? ? ? ? 2.422 ? ? 
metalc25 metalc ? ? C HIS   132 NE2 ? ? ? 1_555 O CO . CO ? ? L HIS   118 L CO 302 1_555 ? ? ? ? ? ? ? 2.084 ? ? 
metalc26 metalc ? ? C HIS   134 ND1 ? ? ? 1_555 O CO . CO ? ? L HIS   120 L CO 302 1_555 ? ? ? ? ? ? ? 2.099 ? ? 
metalc27 metalc ? ? C ASP   136 OD2 ? ? ? 1_555 P FE . FE ? ? L ASP   122 L FE 303 1_555 ? ? ? ? ? ? ? 2.166 ? ? 
metalc28 metalc ? ? C HIS   137 NE2 ? ? ? 1_555 P FE . FE ? ? L HIS   123 L FE 303 1_555 ? ? ? ? ? ? ? 2.179 ? ? 
metalc29 metalc ? ? C HIS   212 NE2 ? ? ? 1_555 O CO . CO ? ? L HIS   198 L CO 302 1_555 ? ? ? ? ? ? ? 2.099 ? ? 
metalc30 metalc ? ? C ASP   234 OD2 ? ? ? 1_555 O CO . CO ? ? L ASP   220 L CO 302 1_555 ? ? ? ? ? ? ? 2.352 ? ? 
metalc31 metalc ? ? C ASP   234 OD2 ? ? ? 1_555 P FE . FE ? ? L ASP   220 L FE 303 1_555 ? ? ? ? ? ? ? 2.236 ? ? 
metalc32 metalc ? ? C HIS   280 NE2 ? ? ? 1_555 P FE . FE ? ? L HIS   266 L FE 303 1_555 ? ? ? ? ? ? ? 2.252 ? ? 
metalc33 metalc ? ? N A1AI3 .   O   ? ? ? 1_555 O CO . CO ? ? L A1AI3 301 L CO 302 1_555 ? ? ? ? ? ? ? 2.044 ? ? 
metalc34 metalc ? ? N A1AI3 .   O   ? ? ? 1_555 P FE . FE ? ? L A1AI3 301 L FE 303 1_555 ? ? ? ? ? ? ? 2.798 ? ? 
metalc35 metalc ? ? N A1AI3 .   OAQ ? ? ? 1_555 P FE . FE ? ? L A1AI3 301 L FE 303 1_555 ? ? ? ? ? ? ? 2.671 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  NE2 ? A HIS   132 ? X HIS   118 ? 1_555 CO ? E CO . ? X CO 302 ? 1_555 ND1 ? A HIS   134 ? X HIS   120 ? 1_555 93.7  ? 
2  NE2 ? A HIS   132 ? X HIS   118 ? 1_555 CO ? E CO . ? X CO 302 ? 1_555 NE2 ? A HIS   212 ? X HIS   198 ? 1_555 109.9 ? 
3  ND1 ? A HIS   134 ? X HIS   120 ? 1_555 CO ? E CO . ? X CO 302 ? 1_555 NE2 ? A HIS   212 ? X HIS   198 ? 1_555 94.7  ? 
4  NE2 ? A HIS   132 ? X HIS   118 ? 1_555 CO ? E CO . ? X CO 302 ? 1_555 OD2 ? A ASP   234 ? X ASP   220 ? 1_555 95.0  ? 
5  ND1 ? A HIS   134 ? X HIS   120 ? 1_555 CO ? E CO . ? X CO 302 ? 1_555 OD2 ? A ASP   234 ? X ASP   220 ? 1_555 166.8 ? 
6  NE2 ? A HIS   212 ? X HIS   198 ? 1_555 CO ? E CO . ? X CO 302 ? 1_555 OD2 ? A ASP   234 ? X ASP   220 ? 1_555 91.7  ? 
7  NE2 ? A HIS   132 ? X HIS   118 ? 1_555 CO ? E CO . ? X CO 302 ? 1_555 OXT ? D A1AI3 .   ? X A1AI3 301 ? 1_555 123.5 ? 
8  ND1 ? A HIS   134 ? X HIS   120 ? 1_555 CO ? E CO . ? X CO 302 ? 1_555 OXT ? D A1AI3 .   ? X A1AI3 301 ? 1_555 93.3  ? 
9  NE2 ? A HIS   212 ? X HIS   198 ? 1_555 CO ? E CO . ? X CO 302 ? 1_555 OXT ? D A1AI3 .   ? X A1AI3 301 ? 1_555 125.3 ? 
10 OD2 ? A ASP   234 ? X ASP   220 ? 1_555 CO ? E CO . ? X CO 302 ? 1_555 OXT ? D A1AI3 .   ? X A1AI3 301 ? 1_555 73.6  ? 
11 NE2 ? A HIS   132 ? X HIS   118 ? 1_555 CO ? E CO . ? X CO 302 ? 1_555 O   ? D A1AI3 .   ? X A1AI3 301 ? 1_555 177.0 ? 
12 ND1 ? A HIS   134 ? X HIS   120 ? 1_555 CO ? E CO . ? X CO 302 ? 1_555 O   ? D A1AI3 .   ? X A1AI3 301 ? 1_555 85.5  ? 
13 NE2 ? A HIS   212 ? X HIS   198 ? 1_555 CO ? E CO . ? X CO 302 ? 1_555 O   ? D A1AI3 .   ? X A1AI3 301 ? 1_555 73.1  ? 
14 OD2 ? A ASP   234 ? X ASP   220 ? 1_555 CO ? E CO . ? X CO 302 ? 1_555 O   ? D A1AI3 .   ? X A1AI3 301 ? 1_555 85.3  ? 
15 OXT ? D A1AI3 .   ? X A1AI3 301 ? 1_555 CO ? E CO . ? X CO 302 ? 1_555 O   ? D A1AI3 .   ? X A1AI3 301 ? 1_555 53.7  ? 
16 OD2 ? A ASP   136 ? X ASP   122 ? 1_555 FE ? H FE . ? X FE 305 ? 1_555 NE2 ? A HIS   137 ? X HIS   123 ? 1_555 87.5  ? 
17 OD2 ? A ASP   136 ? X ASP   122 ? 1_555 FE ? H FE . ? X FE 305 ? 1_555 OD2 ? A ASP   234 ? X ASP   220 ? 1_555 147.0 ? 
18 NE2 ? A HIS   137 ? X HIS   123 ? 1_555 FE ? H FE . ? X FE 305 ? 1_555 OD2 ? A ASP   234 ? X ASP   220 ? 1_555 89.0  ? 
19 OD2 ? A ASP   136 ? X ASP   122 ? 1_555 FE ? H FE . ? X FE 305 ? 1_555 NE2 ? A HIS   280 ? X HIS   266 ? 1_555 90.8  ? 
20 NE2 ? A HIS   137 ? X HIS   123 ? 1_555 FE ? H FE . ? X FE 305 ? 1_555 NE2 ? A HIS   280 ? X HIS   266 ? 1_555 106.4 ? 
21 OD2 ? A ASP   234 ? X ASP   220 ? 1_555 FE ? H FE . ? X FE 305 ? 1_555 NE2 ? A HIS   280 ? X HIS   266 ? 1_555 121.6 ? 
22 OD2 ? A ASP   136 ? X ASP   122 ? 1_555 FE ? H FE . ? X FE 305 ? 1_555 OXT ? D A1AI3 .   ? X A1AI3 301 ? 1_555 78.4  ? 
23 NE2 ? A HIS   137 ? X HIS   123 ? 1_555 FE ? H FE . ? X FE 305 ? 1_555 OXT ? D A1AI3 .   ? X A1AI3 301 ? 1_555 101.4 ? 
24 OD2 ? A ASP   234 ? X ASP   220 ? 1_555 FE ? H FE . ? X FE 305 ? 1_555 OXT ? D A1AI3 .   ? X A1AI3 301 ? 1_555 70.2  ? 
25 NE2 ? A HIS   280 ? X HIS   266 ? 1_555 FE ? H FE . ? X FE 305 ? 1_555 OXT ? D A1AI3 .   ? X A1AI3 301 ? 1_555 149.7 ? 
26 OD2 ? A ASP   136 ? X ASP   122 ? 1_555 FE ? H FE . ? X FE 305 ? 1_555 OAQ ? D A1AI3 .   ? X A1AI3 301 ? 1_555 87.6  ? 
27 NE2 ? A HIS   137 ? X HIS   123 ? 1_555 FE ? H FE . ? X FE 305 ? 1_555 OAQ ? D A1AI3 .   ? X A1AI3 301 ? 1_555 168.6 ? 
28 OD2 ? A ASP   234 ? X ASP   220 ? 1_555 FE ? H FE . ? X FE 305 ? 1_555 OAQ ? D A1AI3 .   ? X A1AI3 301 ? 1_555 89.5  ? 
29 NE2 ? A HIS   280 ? X HIS   266 ? 1_555 FE ? H FE . ? X FE 305 ? 1_555 OAQ ? D A1AI3 .   ? X A1AI3 301 ? 1_555 84.0  ? 
30 OXT ? D A1AI3 .   ? X A1AI3 301 ? 1_555 FE ? H FE . ? X FE 305 ? 1_555 OAQ ? D A1AI3 .   ? X A1AI3 301 ? 1_555 67.5  ? 
31 NE2 ? B HIS   132 ? F HIS   118 ? 1_555 CO ? J CO . ? F CO 302 ? 1_555 ND1 ? B HIS   134 ? F HIS   120 ? 1_555 93.5  ? 
32 NE2 ? B HIS   132 ? F HIS   118 ? 1_555 CO ? J CO . ? F CO 302 ? 1_555 NE2 ? B HIS   212 ? F HIS   198 ? 1_555 107.1 ? 
33 ND1 ? B HIS   134 ? F HIS   120 ? 1_555 CO ? J CO . ? F CO 302 ? 1_555 NE2 ? B HIS   212 ? F HIS   198 ? 1_555 96.7  ? 
34 NE2 ? B HIS   132 ? F HIS   118 ? 1_555 CO ? J CO . ? F CO 302 ? 1_555 OD2 ? B ASP   234 ? F ASP   220 ? 1_555 92.2  ? 
35 ND1 ? B HIS   134 ? F HIS   120 ? 1_555 CO ? J CO . ? F CO 302 ? 1_555 OD2 ? B ASP   234 ? F ASP   220 ? 1_555 170.0 ? 
36 NE2 ? B HIS   212 ? F HIS   198 ? 1_555 CO ? J CO . ? F CO 302 ? 1_555 OD2 ? B ASP   234 ? F ASP   220 ? 1_555 89.5  ? 
37 NE2 ? B HIS   132 ? F HIS   118 ? 1_555 CO ? J CO . ? F CO 302 ? 1_555 OXT ? I A1AI3 .   ? F A1AI3 301 ? 1_555 176.9 ? 
38 ND1 ? B HIS   134 ? F HIS   120 ? 1_555 CO ? J CO . ? F CO 302 ? 1_555 OXT ? I A1AI3 .   ? F A1AI3 301 ? 1_555 83.3  ? 
39 NE2 ? B HIS   212 ? F HIS   198 ? 1_555 CO ? J CO . ? F CO 302 ? 1_555 OXT ? I A1AI3 .   ? F A1AI3 301 ? 1_555 73.1  ? 
40 OD2 ? B ASP   234 ? F ASP   220 ? 1_555 CO ? J CO . ? F CO 302 ? 1_555 OXT ? I A1AI3 .   ? F A1AI3 301 ? 1_555 91.0  ? 
41 NE2 ? B HIS   132 ? F HIS   118 ? 1_555 CO ? J CO . ? F CO 302 ? 1_555 O   ? I A1AI3 .   ? F A1AI3 301 ? 1_555 127.1 ? 
42 ND1 ? B HIS   134 ? F HIS   120 ? 1_555 CO ? J CO . ? F CO 302 ? 1_555 O   ? I A1AI3 .   ? F A1AI3 301 ? 1_555 95.0  ? 
43 NE2 ? B HIS   212 ? F HIS   198 ? 1_555 CO ? J CO . ? F CO 302 ? 1_555 O   ? I A1AI3 .   ? F A1AI3 301 ? 1_555 123.5 ? 
44 OD2 ? B ASP   234 ? F ASP   220 ? 1_555 CO ? J CO . ? F CO 302 ? 1_555 O   ? I A1AI3 .   ? F A1AI3 301 ? 1_555 75.0  ? 
45 OXT ? I A1AI3 .   ? F A1AI3 301 ? 1_555 CO ? J CO . ? F CO 302 ? 1_555 O   ? I A1AI3 .   ? F A1AI3 301 ? 1_555 53.8  ? 
46 OD2 ? B ASP   136 ? F ASP   122 ? 1_555 FE ? K FE . ? F FE 303 ? 1_555 NE2 ? B HIS   137 ? F HIS   123 ? 1_555 84.7  ? 
47 OD2 ? B ASP   136 ? F ASP   122 ? 1_555 FE ? K FE . ? F FE 303 ? 1_555 OD2 ? B ASP   234 ? F ASP   220 ? 1_555 151.4 ? 
48 NE2 ? B HIS   137 ? F HIS   123 ? 1_555 FE ? K FE . ? F FE 303 ? 1_555 OD2 ? B ASP   234 ? F ASP   220 ? 1_555 87.0  ? 
49 OD2 ? B ASP   136 ? F ASP   122 ? 1_555 FE ? K FE . ? F FE 303 ? 1_555 NE2 ? B HIS   280 ? F HIS   266 ? 1_555 88.5  ? 
50 NE2 ? B HIS   137 ? F HIS   123 ? 1_555 FE ? K FE . ? F FE 303 ? 1_555 NE2 ? B HIS   280 ? F HIS   266 ? 1_555 102.2 ? 
51 OD2 ? B ASP   234 ? F ASP   220 ? 1_555 FE ? K FE . ? F FE 303 ? 1_555 NE2 ? B HIS   280 ? F HIS   266 ? 1_555 120.0 ? 
52 OD2 ? B ASP   136 ? F ASP   122 ? 1_555 FE ? K FE . ? F FE 303 ? 1_555 O   ? I A1AI3 .   ? F A1AI3 301 ? 1_555 86.9  ? 
53 NE2 ? B HIS   137 ? F HIS   123 ? 1_555 FE ? K FE . ? F FE 303 ? 1_555 O   ? I A1AI3 .   ? F A1AI3 301 ? 1_555 104.7 ? 
54 OD2 ? B ASP   234 ? F ASP   220 ? 1_555 FE ? K FE . ? F FE 303 ? 1_555 O   ? I A1AI3 .   ? F A1AI3 301 ? 1_555 68.8  ? 
55 NE2 ? B HIS   280 ? F HIS   266 ? 1_555 FE ? K FE . ? F FE 303 ? 1_555 O   ? I A1AI3 .   ? F A1AI3 301 ? 1_555 152.2 ? 
56 OD2 ? B ASP   136 ? F ASP   122 ? 1_555 FE ? K FE . ? F FE 303 ? 1_555 OAQ ? I A1AI3 .   ? F A1AI3 301 ? 1_555 93.6  ? 
57 NE2 ? B HIS   137 ? F HIS   123 ? 1_555 FE ? K FE . ? F FE 303 ? 1_555 OAQ ? I A1AI3 .   ? F A1AI3 301 ? 1_555 171.7 ? 
58 OD2 ? B ASP   234 ? F ASP   220 ? 1_555 FE ? K FE . ? F FE 303 ? 1_555 OAQ ? I A1AI3 .   ? F A1AI3 301 ? 1_555 90.6  ? 
59 NE2 ? B HIS   280 ? F HIS   266 ? 1_555 FE ? K FE . ? F FE 303 ? 1_555 OAQ ? I A1AI3 .   ? F A1AI3 301 ? 1_555 85.9  ? 
60 O   ? I A1AI3 .   ? F A1AI3 301 ? 1_555 FE ? K FE . ? F FE 303 ? 1_555 OAQ ? I A1AI3 .   ? F A1AI3 301 ? 1_555 67.1  ? 
61 NE2 ? C HIS   132 ? L HIS   118 ? 1_555 CO ? O CO . ? L CO 302 ? 1_555 ND1 ? C HIS   134 ? L HIS   120 ? 1_555 92.6  ? 
62 NE2 ? C HIS   132 ? L HIS   118 ? 1_555 CO ? O CO . ? L CO 302 ? 1_555 NE2 ? C HIS   212 ? L HIS   198 ? 1_555 106.9 ? 
63 ND1 ? C HIS   134 ? L HIS   120 ? 1_555 CO ? O CO . ? L CO 302 ? 1_555 NE2 ? C HIS   212 ? L HIS   198 ? 1_555 96.6  ? 
64 NE2 ? C HIS   132 ? L HIS   118 ? 1_555 CO ? O CO . ? L CO 302 ? 1_555 OD2 ? C ASP   234 ? L ASP   220 ? 1_555 92.8  ? 
65 ND1 ? C HIS   134 ? L HIS   120 ? 1_555 CO ? O CO . ? L CO 302 ? 1_555 OD2 ? C ASP   234 ? L ASP   220 ? 1_555 169.5 ? 
66 NE2 ? C HIS   212 ? L HIS   198 ? 1_555 CO ? O CO . ? L CO 302 ? 1_555 OD2 ? C ASP   234 ? L ASP   220 ? 1_555 90.5  ? 
67 NE2 ? C HIS   132 ? L HIS   118 ? 1_555 CO ? O CO . ? L CO 302 ? 1_555 O   ? N A1AI3 .   ? L A1AI3 301 ? 1_555 121.1 ? 
68 ND1 ? C HIS   134 ? L HIS   120 ? 1_555 CO ? O CO . ? L CO 302 ? 1_555 O   ? N A1AI3 .   ? L A1AI3 301 ? 1_555 86.7  ? 
69 NE2 ? C HIS   212 ? L HIS   198 ? 1_555 CO ? O CO . ? L CO 302 ? 1_555 O   ? N A1AI3 .   ? L A1AI3 301 ? 1_555 131.7 ? 
70 OD2 ? C ASP   234 ? L ASP   220 ? 1_555 CO ? O CO . ? L CO 302 ? 1_555 O   ? N A1AI3 .   ? L A1AI3 301 ? 1_555 82.8  ? 
71 OD2 ? C ASP   136 ? L ASP   122 ? 1_555 FE ? P FE . ? L FE 303 ? 1_555 NE2 ? C HIS   137 ? L HIS   123 ? 1_555 87.8  ? 
72 OD2 ? C ASP   136 ? L ASP   122 ? 1_555 FE ? P FE . ? L FE 303 ? 1_555 OD2 ? C ASP   234 ? L ASP   220 ? 1_555 151.9 ? 
73 NE2 ? C HIS   137 ? L HIS   123 ? 1_555 FE ? P FE . ? L FE 303 ? 1_555 OD2 ? C ASP   234 ? L ASP   220 ? 1_555 85.8  ? 
74 OD2 ? C ASP   136 ? L ASP   122 ? 1_555 FE ? P FE . ? L FE 303 ? 1_555 NE2 ? C HIS   280 ? L HIS   266 ? 1_555 88.6  ? 
75 NE2 ? C HIS   137 ? L HIS   123 ? 1_555 FE ? P FE . ? L FE 303 ? 1_555 NE2 ? C HIS   280 ? L HIS   266 ? 1_555 99.8  ? 
76 OD2 ? C ASP   234 ? L ASP   220 ? 1_555 FE ? P FE . ? L FE 303 ? 1_555 NE2 ? C HIS   280 ? L HIS   266 ? 1_555 119.4 ? 
77 OD2 ? C ASP   136 ? L ASP   122 ? 1_555 FE ? P FE . ? L FE 303 ? 1_555 O   ? N A1AI3 .   ? L A1AI3 301 ? 1_555 84.5  ? 
78 NE2 ? C HIS   137 ? L HIS   123 ? 1_555 FE ? P FE . ? L FE 303 ? 1_555 O   ? N A1AI3 .   ? L A1AI3 301 ? 1_555 99.9  ? 
79 OD2 ? C ASP   234 ? L ASP   220 ? 1_555 FE ? P FE . ? L FE 303 ? 1_555 O   ? N A1AI3 .   ? L A1AI3 301 ? 1_555 69.8  ? 
80 NE2 ? C HIS   280 ? L HIS   266 ? 1_555 FE ? P FE . ? L FE 303 ? 1_555 O   ? N A1AI3 .   ? L A1AI3 301 ? 1_555 158.8 ? 
81 OD2 ? C ASP   136 ? L ASP   122 ? 1_555 FE ? P FE . ? L FE 303 ? 1_555 OAQ ? N A1AI3 .   ? L A1AI3 301 ? 1_555 84.2  ? 
82 NE2 ? C HIS   137 ? L HIS   123 ? 1_555 FE ? P FE . ? L FE 303 ? 1_555 OAQ ? N A1AI3 .   ? L A1AI3 301 ? 1_555 171.9 ? 
83 OD2 ? C ASP   234 ? L ASP   220 ? 1_555 FE ? P FE . ? L FE 303 ? 1_555 OAQ ? N A1AI3 .   ? L A1AI3 301 ? 1_555 100.6 ? 
84 NE2 ? C HIS   280 ? L HIS   266 ? 1_555 FE ? P FE . ? L FE 303 ? 1_555 OAQ ? N A1AI3 .   ? L A1AI3 301 ? 1_555 81.6  ? 
85 O   ? N A1AI3 .   ? L A1AI3 301 ? 1_555 FE ? P FE . ? L FE 303 ? 1_555 OAQ ? N A1AI3 .   ? L A1AI3 301 ? 1_555 77.8  ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 GLY 243 A . ? GLY 229 X PRO 244 A ? PRO 230 X 1 8.28 
2 PRO 244 A . ? PRO 230 X PRO 245 A ? PRO 231 X 1 0.75 
3 GLY 243 B . ? GLY 229 F PRO 244 B ? PRO 230 F 1 5.53 
4 PRO 244 B . ? PRO 230 F PRO 245 B ? PRO 231 F 1 1.15 
5 GLY 243 C . ? GLY 229 L PRO 244 C ? PRO 230 L 1 8.39 
6 PRO 244 C . ? PRO 230 L PRO 245 C ? PRO 231 L 1 5.13 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 7 ? 
AA2 ? 5 ? 
AA3 ? 7 ? 
AA4 ? 5 ? 
AA5 ? 7 ? 
AA6 ? 5 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA1 6 7 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? parallel      
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA3 4 5 ? parallel      
AA3 5 6 ? parallel      
AA3 6 7 ? parallel      
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? parallel      
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? parallel      
AA5 5 6 ? parallel      
AA5 6 7 ? parallel      
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA6 4 5 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 TRP A 103 ? THR A 104 ? TRP X 89  THR X 90  
AA1 2 LYS A 25  ? ASP A 37  ? LYS X 11  ASP X 23  
AA1 3 PHE A 59  ? ASP A 70  ? PHE X 45  ASP X 56  
AA1 4 LYS A 75  ? PHE A 78  ? LYS X 61  PHE X 64  
AA1 5 ILE A 125 ? VAL A 129 ? ILE X 111 VAL X 115 
AA1 6 THR A 148 ? HIS A 152 ? THR X 134 HIS X 138 
AA1 7 GLN A 186 ? VAL A 190 ? GLN X 172 VAL X 176 
AA2 1 ILE A 197 ? ALA A 200 ? ILE X 183 ALA X 186 
AA2 2 VAL A 203 ? GLY A 209 ? VAL X 189 GLY X 195 
AA2 3 MET A 216 ? LEU A 223 ? MET X 202 LEU X 209 
AA2 4 GLY A 227 ? SER A 233 ? GLY X 213 SER X 219 
AA2 5 SER A 274 ? PHE A 278 ? SER X 260 PHE X 264 
AA3 1 TRP B 103 ? THR B 104 ? TRP F 89  THR F 90  
AA3 2 LYS B 25  ? ASP B 37  ? LYS F 11  ASP F 23  
AA3 3 PHE B 59  ? ASP B 70  ? PHE F 45  ASP F 56  
AA3 4 LYS B 75  ? PHE B 78  ? LYS F 61  PHE F 64  
AA3 5 ILE B 125 ? VAL B 129 ? ILE F 111 VAL F 115 
AA3 6 THR B 148 ? HIS B 152 ? THR F 134 HIS F 138 
AA3 7 GLN B 186 ? VAL B 190 ? GLN F 172 VAL F 176 
AA4 1 ILE B 197 ? ALA B 200 ? ILE F 183 ALA F 186 
AA4 2 VAL B 203 ? GLY B 209 ? VAL F 189 GLY F 195 
AA4 3 MET B 216 ? LEU B 223 ? MET F 202 LEU F 209 
AA4 4 GLY B 227 ? SER B 233 ? GLY F 213 SER F 219 
AA4 5 SER B 274 ? PHE B 278 ? SER F 260 PHE F 264 
AA5 1 TRP C 103 ? THR C 104 ? TRP L 89  THR L 90  
AA5 2 LYS C 25  ? ASP C 37  ? LYS L 11  ASP L 23  
AA5 3 PHE C 59  ? ASP C 70  ? PHE L 45  ASP L 56  
AA5 4 LYS C 75  ? PHE C 78  ? LYS L 61  PHE L 64  
AA5 5 ILE C 125 ? VAL C 129 ? ILE L 111 VAL L 115 
AA5 6 THR C 148 ? HIS C 152 ? THR L 134 HIS L 138 
AA5 7 GLN C 186 ? VAL C 190 ? GLN L 172 VAL L 176 
AA6 1 ILE C 197 ? ALA C 200 ? ILE L 183 ALA L 186 
AA6 2 VAL C 203 ? GLY C 209 ? VAL L 189 GLY L 195 
AA6 3 MET C 216 ? LEU C 223 ? MET L 202 LEU L 209 
AA6 4 GLY C 227 ? SER C 233 ? GLY L 213 SER L 219 
AA6 5 SER C 274 ? PHE C 278 ? SER L 260 PHE L 264 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O THR A 104 ? O THR X 90  N ARG A 33  ? N ARG X 19  
AA1 2 3 N LYS A 25  ? N LYS X 11  O ASP A 70  ? O ASP X 56  
AA1 3 4 N ILE A 69  ? N ILE X 55  O ILE A 76  ? O ILE X 62  
AA1 4 5 N LEU A 77  ? N LEU X 63  O VAL A 129 ? O VAL X 115 
AA1 5 6 N VAL A 128 ? N VAL X 114 O ILE A 150 ? O ILE X 136 
AA1 6 7 N ILE A 149 ? N ILE X 135 O GLN A 186 ? O GLN X 172 
AA2 1 2 N ILE A 197 ? N ILE X 183 O VAL A 205 ? O VAL X 191 
AA2 2 3 N LYS A 204 ? N LYS X 190 O HIS A 220 ? O HIS X 206 
AA2 3 4 N VAL A 221 ? N VAL X 207 O ILE A 229 ? O ILE X 215 
AA2 4 5 N ILE A 230 ? N ILE X 216 O TRP A 277 ? O TRP X 263 
AA3 1 2 O THR B 104 ? O THR F 90  N ARG B 33  ? N ARG F 19  
AA3 2 3 N LYS B 25  ? N LYS F 11  O ASP B 70  ? O ASP F 56  
AA3 3 4 N ILE B 69  ? N ILE F 55  O ILE B 76  ? O ILE F 62  
AA3 4 5 N LEU B 77  ? N LEU F 63  O VAL B 129 ? O VAL F 115 
AA3 5 6 N VAL B 128 ? N VAL F 114 O ILE B 150 ? O ILE F 136 
AA3 6 7 N ILE B 149 ? N ILE F 135 O GLN B 186 ? O GLN F 172 
AA4 1 2 N ILE B 197 ? N ILE F 183 O VAL B 205 ? O VAL F 191 
AA4 2 3 N LYS B 204 ? N LYS F 190 O HIS B 220 ? O HIS F 206 
AA4 3 4 N VAL B 221 ? N VAL F 207 O ILE B 229 ? O ILE F 215 
AA4 4 5 N ILE B 230 ? N ILE F 216 O TRP B 277 ? O TRP F 263 
AA5 1 2 O THR C 104 ? O THR L 90  N ARG C 33  ? N ARG L 19  
AA5 2 3 N LYS C 25  ? N LYS L 11  O ASP C 70  ? O ASP L 56  
AA5 3 4 N ILE C 69  ? N ILE L 55  O ILE C 76  ? O ILE L 62  
AA5 4 5 N LEU C 77  ? N LEU L 63  O VAL C 129 ? O VAL L 115 
AA5 5 6 N VAL C 128 ? N VAL L 114 O ILE C 150 ? O ILE L 136 
AA5 6 7 N ILE C 149 ? N ILE L 135 O GLN C 186 ? O GLN L 172 
AA6 1 2 N ILE C 197 ? N ILE L 183 O VAL C 205 ? O VAL L 191 
AA6 2 3 N LYS C 204 ? N LYS L 190 O HIS C 220 ? O HIS L 206 
AA6 3 4 N VAL C 221 ? N VAL L 207 O ILE C 229 ? O ILE L 215 
AA6 4 5 N ILE C 230 ? N ILE L 216 O TRP C 277 ? O TRP L 263 
# 
_pdbx_entry_details.entry_id                   9B2O 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   O 
_pdbx_validate_close_contact.auth_asym_id_1   L 
_pdbx_validate_close_contact.auth_comp_id_1   HOH 
_pdbx_validate_close_contact.auth_seq_id_1    402 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   O 
_pdbx_validate_close_contact.auth_asym_id_2   L 
_pdbx_validate_close_contact.auth_comp_id_2   HOH 
_pdbx_validate_close_contact.auth_seq_id_2    496 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             2.13 
# 
loop_
_pdbx_validate_symm_contact.id 
_pdbx_validate_symm_contact.PDB_model_num 
_pdbx_validate_symm_contact.auth_atom_id_1 
_pdbx_validate_symm_contact.auth_asym_id_1 
_pdbx_validate_symm_contact.auth_comp_id_1 
_pdbx_validate_symm_contact.auth_seq_id_1 
_pdbx_validate_symm_contact.PDB_ins_code_1 
_pdbx_validate_symm_contact.label_alt_id_1 
_pdbx_validate_symm_contact.site_symmetry_1 
_pdbx_validate_symm_contact.auth_atom_id_2 
_pdbx_validate_symm_contact.auth_asym_id_2 
_pdbx_validate_symm_contact.auth_comp_id_2 
_pdbx_validate_symm_contact.auth_seq_id_2 
_pdbx_validate_symm_contact.PDB_ins_code_2 
_pdbx_validate_symm_contact.label_alt_id_2 
_pdbx_validate_symm_contact.site_symmetry_2 
_pdbx_validate_symm_contact.dist 
1 1 O F HOH 464 ? ? 1_555 O F HOH 464 ? ? 2_556 1.72 
2 1 O X HOH 518 ? ? 1_555 O X HOH 518 ? ? 2_555 2.16 
# 
loop_
_pdbx_validate_rmsd_bond.id 
_pdbx_validate_rmsd_bond.PDB_model_num 
_pdbx_validate_rmsd_bond.auth_atom_id_1 
_pdbx_validate_rmsd_bond.auth_asym_id_1 
_pdbx_validate_rmsd_bond.auth_comp_id_1 
_pdbx_validate_rmsd_bond.auth_seq_id_1 
_pdbx_validate_rmsd_bond.PDB_ins_code_1 
_pdbx_validate_rmsd_bond.label_alt_id_1 
_pdbx_validate_rmsd_bond.auth_atom_id_2 
_pdbx_validate_rmsd_bond.auth_asym_id_2 
_pdbx_validate_rmsd_bond.auth_comp_id_2 
_pdbx_validate_rmsd_bond.auth_seq_id_2 
_pdbx_validate_rmsd_bond.PDB_ins_code_2 
_pdbx_validate_rmsd_bond.label_alt_id_2 
_pdbx_validate_rmsd_bond.bond_value 
_pdbx_validate_rmsd_bond.bond_target_value 
_pdbx_validate_rmsd_bond.bond_deviation 
_pdbx_validate_rmsd_bond.bond_standard_deviation 
_pdbx_validate_rmsd_bond.linker_flag 
1 1 CD F GLU 139 ? ? OE2 F GLU 139 ? ? 1.336 1.252 0.084 0.011 N 
2 1 CD L GLU 139 ? ? OE2 L GLU 139 ? ? 1.340 1.252 0.088 0.011 N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 CA X GLU 283 ? ? C X GLU 283 ? ? O X GLU 283 ? ? 103.21 120.10 -16.89 2.10 N 
2 1 CA F GLU 283 ? ? C F GLU 283 ? ? O F GLU 283 ? ? 101.71 120.10 -18.39 2.10 N 
3 1 CA L GLU 283 ? ? C L GLU 283 ? ? O L GLU 283 ? ? 100.28 120.10 -19.82 2.10 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ASP X 65  ? ? 74.78   166.94  
2  1 SER X 67  ? ? 59.63   -151.67 
3  1 HIS X 123 ? ? -131.05 -31.35  
4  1 ASP X 181 ? ? -38.32  -172.85 
5  1 SER X 219 ? ? 46.89   -137.15 
6  1 HIS X 266 ? ? -150.86 47.07   
7  1 ASP F 65  ? ? 73.87   167.69  
8  1 SER F 67  ? ? 60.27   -154.96 
9  1 HIS F 118 ? ? -171.24 -179.15 
10 1 ASP F 181 ? ? -40.45  -178.06 
11 1 SER F 219 ? ? 46.94   -134.61 
12 1 HIS F 266 ? ? -149.63 45.83   
13 1 ASN L 32  ? ? -153.02 71.78   
14 1 ASP L 65  ? ? 70.78   168.30  
15 1 SER L 67  ? ? 61.40   -154.44 
16 1 HIS L 118 ? ? -171.69 -178.11 
17 1 SER L 219 ? ? 46.46   -133.63 
18 1 HIS L 266 ? ? -150.54 47.59   
# 
loop_
_pdbx_struct_special_symmetry.id 
_pdbx_struct_special_symmetry.PDB_model_num 
_pdbx_struct_special_symmetry.auth_asym_id 
_pdbx_struct_special_symmetry.auth_comp_id 
_pdbx_struct_special_symmetry.auth_seq_id 
_pdbx_struct_special_symmetry.PDB_ins_code 
_pdbx_struct_special_symmetry.label_asym_id 
_pdbx_struct_special_symmetry.label_comp_id 
_pdbx_struct_special_symmetry.label_seq_id 
1 1 L HOH 411 ? T HOH . 
2 1 L HOH 435 ? T HOH . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 X TRP -13 ? A TRP 1  
2  1 Y 1 X SER -12 ? A SER 2  
3  1 Y 1 X HIS -11 ? A HIS 3  
4  1 Y 1 X PRO -10 ? A PRO 4  
5  1 Y 1 X GLN -9  ? A GLN 5  
6  1 Y 1 X PHE -8  ? A PHE 6  
7  1 Y 1 X GLU -7  ? A GLU 7  
8  1 Y 1 X LYS -6  ? A LYS 8  
9  1 Y 1 X GLU -5  ? A GLU 9  
10 1 Y 1 X ASN -4  ? A ASN 10 
11 1 Y 1 X LEU -3  ? A LEU 11 
12 1 Y 1 X TYR -2  ? A TYR 12 
13 1 Y 1 X PHE -1  ? A PHE 13 
14 1 Y 1 X GLN 0   ? A GLN 14 
15 1 Y 1 X SER 1   ? A SER 15 
16 1 Y 1 X MET 2   ? A MET 16 
17 1 Y 1 X ALA 3   ? A ALA 17 
18 1 Y 1 X ASN 4   ? A ASN 18 
19 1 Y 1 X VAL 5   ? A VAL 19 
20 1 Y 1 X ILE 6   ? A ILE 20 
21 1 Y 1 X LYS 7   ? A LYS 21 
22 1 Y 1 F TRP -13 ? B TRP 1  
23 1 Y 1 F SER -12 ? B SER 2  
24 1 Y 1 F HIS -11 ? B HIS 3  
25 1 Y 1 F PRO -10 ? B PRO 4  
26 1 Y 1 F GLN -9  ? B GLN 5  
27 1 Y 1 F PHE -8  ? B PHE 6  
28 1 Y 1 F GLU -7  ? B GLU 7  
29 1 Y 1 F LYS -6  ? B LYS 8  
30 1 Y 1 F GLU -5  ? B GLU 9  
31 1 Y 1 F ASN -4  ? B ASN 10 
32 1 Y 1 F LEU -3  ? B LEU 11 
33 1 Y 1 F TYR -2  ? B TYR 12 
34 1 Y 1 F PHE -1  ? B PHE 13 
35 1 Y 1 F GLN 0   ? B GLN 14 
36 1 Y 1 F SER 1   ? B SER 15 
37 1 Y 1 F MET 2   ? B MET 16 
38 1 Y 1 F ALA 3   ? B ALA 17 
39 1 Y 1 F ASN 4   ? B ASN 18 
40 1 Y 1 F VAL 5   ? B VAL 19 
41 1 Y 1 F ILE 6   ? B ILE 20 
42 1 Y 1 F LYS 7   ? B LYS 21 
43 1 Y 1 L TRP -13 ? C TRP 1  
44 1 Y 1 L SER -12 ? C SER 2  
45 1 Y 1 L HIS -11 ? C HIS 3  
46 1 Y 1 L PRO -10 ? C PRO 4  
47 1 Y 1 L GLN -9  ? C GLN 5  
48 1 Y 1 L PHE -8  ? C PHE 6  
49 1 Y 1 L GLU -7  ? C GLU 7  
50 1 Y 1 L LYS -6  ? C LYS 8  
51 1 Y 1 L GLU -5  ? C GLU 9  
52 1 Y 1 L ASN -4  ? C ASN 10 
53 1 Y 1 L LEU -3  ? C LEU 11 
54 1 Y 1 L TYR -2  ? C TYR 12 
55 1 Y 1 L PHE -1  ? C PHE 13 
56 1 Y 1 L GLN 0   ? C GLN 14 
57 1 Y 1 L SER 1   ? C SER 15 
58 1 Y 1 L MET 2   ? C MET 16 
59 1 Y 1 L ALA 3   ? C ALA 17 
60 1 Y 1 L ASN 4   ? C ASN 18 
61 1 Y 1 L VAL 5   ? C VAL 19 
62 1 Y 1 L ILE 6   ? C ILE 20 
63 1 Y 1 L LYS 7   ? C LYS 21 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1AI3 CAJ  C  N N 1   
A1AI3 CAI  C  N N 2   
A1AI3 CAH  C  N N 3   
A1AI3 CAG  C  N N 4   
A1AI3 CAF  C  N N 5   
A1AI3 CAE  C  N N 6   
A1AI3 CAD  C  N N 7   
A1AI3 CAC  C  N N 8   
A1AI3 OAO  O  N N 9   
A1AI3 N    N  N N 10  
A1AI3 CA   C  N S 11  
A1AI3 C    C  N N 12  
A1AI3 OXT  O  N N 13  
A1AI3 O    O  N N 14  
A1AI3 CB   C  N N 15  
A1AI3 CAL  C  N N 16  
A1AI3 OAQ  O  N N 17  
A1AI3 H1   H  N N 18  
A1AI3 H2   H  N N 19  
A1AI3 H3   H  N N 20  
A1AI3 H4   H  N N 21  
A1AI3 H5   H  N N 22  
A1AI3 H6   H  N N 23  
A1AI3 H7   H  N N 24  
A1AI3 H8   H  N N 25  
A1AI3 H9   H  N N 26  
A1AI3 H10  H  N N 27  
A1AI3 H11  H  N N 28  
A1AI3 H12  H  N N 29  
A1AI3 H13  H  N N 30  
A1AI3 H14  H  N N 31  
A1AI3 H15  H  N N 32  
A1AI3 H16  H  N N 33  
A1AI3 H17  H  N N 34  
A1AI3 H18  H  N N 35  
A1AI3 H19  H  N N 36  
A1AI3 H20  H  N N 37  
A1AI3 H21  H  N N 38  
A1AI3 H22  H  N N 39  
A1AI3 H23  H  N N 40  
ALA   N    N  N N 41  
ALA   CA   C  N S 42  
ALA   C    C  N N 43  
ALA   O    O  N N 44  
ALA   CB   C  N N 45  
ALA   OXT  O  N N 46  
ALA   H    H  N N 47  
ALA   H2   H  N N 48  
ALA   HA   H  N N 49  
ALA   HB1  H  N N 50  
ALA   HB2  H  N N 51  
ALA   HB3  H  N N 52  
ALA   HXT  H  N N 53  
ARG   N    N  N N 54  
ARG   CA   C  N S 55  
ARG   C    C  N N 56  
ARG   O    O  N N 57  
ARG   CB   C  N N 58  
ARG   CG   C  N N 59  
ARG   CD   C  N N 60  
ARG   NE   N  N N 61  
ARG   CZ   C  N N 62  
ARG   NH1  N  N N 63  
ARG   NH2  N  N N 64  
ARG   OXT  O  N N 65  
ARG   H    H  N N 66  
ARG   H2   H  N N 67  
ARG   HA   H  N N 68  
ARG   HB2  H  N N 69  
ARG   HB3  H  N N 70  
ARG   HG2  H  N N 71  
ARG   HG3  H  N N 72  
ARG   HD2  H  N N 73  
ARG   HD3  H  N N 74  
ARG   HE   H  N N 75  
ARG   HH11 H  N N 76  
ARG   HH12 H  N N 77  
ARG   HH21 H  N N 78  
ARG   HH22 H  N N 79  
ARG   HXT  H  N N 80  
ASN   N    N  N N 81  
ASN   CA   C  N S 82  
ASN   C    C  N N 83  
ASN   O    O  N N 84  
ASN   CB   C  N N 85  
ASN   CG   C  N N 86  
ASN   OD1  O  N N 87  
ASN   ND2  N  N N 88  
ASN   OXT  O  N N 89  
ASN   H    H  N N 90  
ASN   H2   H  N N 91  
ASN   HA   H  N N 92  
ASN   HB2  H  N N 93  
ASN   HB3  H  N N 94  
ASN   HD21 H  N N 95  
ASN   HD22 H  N N 96  
ASN   HXT  H  N N 97  
ASP   N    N  N N 98  
ASP   CA   C  N S 99  
ASP   C    C  N N 100 
ASP   O    O  N N 101 
ASP   CB   C  N N 102 
ASP   CG   C  N N 103 
ASP   OD1  O  N N 104 
ASP   OD2  O  N N 105 
ASP   OXT  O  N N 106 
ASP   H    H  N N 107 
ASP   H2   H  N N 108 
ASP   HA   H  N N 109 
ASP   HB2  H  N N 110 
ASP   HB3  H  N N 111 
ASP   HD2  H  N N 112 
ASP   HXT  H  N N 113 
CO    CO   CO N N 114 
CYS   N    N  N N 115 
CYS   CA   C  N R 116 
CYS   C    C  N N 117 
CYS   O    O  N N 118 
CYS   CB   C  N N 119 
CYS   SG   S  N N 120 
CYS   OXT  O  N N 121 
CYS   H    H  N N 122 
CYS   H2   H  N N 123 
CYS   HA   H  N N 124 
CYS   HB2  H  N N 125 
CYS   HB3  H  N N 126 
CYS   HG   H  N N 127 
CYS   HXT  H  N N 128 
FE    FE   FE N N 129 
GLN   N    N  N N 130 
GLN   CA   C  N S 131 
GLN   C    C  N N 132 
GLN   O    O  N N 133 
GLN   CB   C  N N 134 
GLN   CG   C  N N 135 
GLN   CD   C  N N 136 
GLN   OE1  O  N N 137 
GLN   NE2  N  N N 138 
GLN   OXT  O  N N 139 
GLN   H    H  N N 140 
GLN   H2   H  N N 141 
GLN   HA   H  N N 142 
GLN   HB2  H  N N 143 
GLN   HB3  H  N N 144 
GLN   HG2  H  N N 145 
GLN   HG3  H  N N 146 
GLN   HE21 H  N N 147 
GLN   HE22 H  N N 148 
GLN   HXT  H  N N 149 
GLU   N    N  N N 150 
GLU   CA   C  N S 151 
GLU   C    C  N N 152 
GLU   O    O  N N 153 
GLU   CB   C  N N 154 
GLU   CG   C  N N 155 
GLU   CD   C  N N 156 
GLU   OE1  O  N N 157 
GLU   OE2  O  N N 158 
GLU   OXT  O  N N 159 
GLU   H    H  N N 160 
GLU   H2   H  N N 161 
GLU   HA   H  N N 162 
GLU   HB2  H  N N 163 
GLU   HB3  H  N N 164 
GLU   HG2  H  N N 165 
GLU   HG3  H  N N 166 
GLU   HE2  H  N N 167 
GLU   HXT  H  N N 168 
GLY   N    N  N N 169 
GLY   CA   C  N N 170 
GLY   C    C  N N 171 
GLY   O    O  N N 172 
GLY   OXT  O  N N 173 
GLY   H    H  N N 174 
GLY   H2   H  N N 175 
GLY   HA2  H  N N 176 
GLY   HA3  H  N N 177 
GLY   HXT  H  N N 178 
HIS   N    N  N N 179 
HIS   CA   C  N S 180 
HIS   C    C  N N 181 
HIS   O    O  N N 182 
HIS   CB   C  N N 183 
HIS   CG   C  Y N 184 
HIS   ND1  N  Y N 185 
HIS   CD2  C  Y N 186 
HIS   CE1  C  Y N 187 
HIS   NE2  N  Y N 188 
HIS   OXT  O  N N 189 
HIS   H    H  N N 190 
HIS   H2   H  N N 191 
HIS   HA   H  N N 192 
HIS   HB2  H  N N 193 
HIS   HB3  H  N N 194 
HIS   HD1  H  N N 195 
HIS   HD2  H  N N 196 
HIS   HE1  H  N N 197 
HIS   HE2  H  N N 198 
HIS   HXT  H  N N 199 
HOH   O    O  N N 200 
HOH   H1   H  N N 201 
HOH   H2   H  N N 202 
ILE   N    N  N N 203 
ILE   CA   C  N S 204 
ILE   C    C  N N 205 
ILE   O    O  N N 206 
ILE   CB   C  N S 207 
ILE   CG1  C  N N 208 
ILE   CG2  C  N N 209 
ILE   CD1  C  N N 210 
ILE   OXT  O  N N 211 
ILE   H    H  N N 212 
ILE   H2   H  N N 213 
ILE   HA   H  N N 214 
ILE   HB   H  N N 215 
ILE   HG12 H  N N 216 
ILE   HG13 H  N N 217 
ILE   HG21 H  N N 218 
ILE   HG22 H  N N 219 
ILE   HG23 H  N N 220 
ILE   HD11 H  N N 221 
ILE   HD12 H  N N 222 
ILE   HD13 H  N N 223 
ILE   HXT  H  N N 224 
LEU   N    N  N N 225 
LEU   CA   C  N S 226 
LEU   C    C  N N 227 
LEU   O    O  N N 228 
LEU   CB   C  N N 229 
LEU   CG   C  N N 230 
LEU   CD1  C  N N 231 
LEU   CD2  C  N N 232 
LEU   OXT  O  N N 233 
LEU   H    H  N N 234 
LEU   H2   H  N N 235 
LEU   HA   H  N N 236 
LEU   HB2  H  N N 237 
LEU   HB3  H  N N 238 
LEU   HG   H  N N 239 
LEU   HD11 H  N N 240 
LEU   HD12 H  N N 241 
LEU   HD13 H  N N 242 
LEU   HD21 H  N N 243 
LEU   HD22 H  N N 244 
LEU   HD23 H  N N 245 
LEU   HXT  H  N N 246 
LYS   N    N  N N 247 
LYS   CA   C  N S 248 
LYS   C    C  N N 249 
LYS   O    O  N N 250 
LYS   CB   C  N N 251 
LYS   CG   C  N N 252 
LYS   CD   C  N N 253 
LYS   CE   C  N N 254 
LYS   NZ   N  N N 255 
LYS   OXT  O  N N 256 
LYS   H    H  N N 257 
LYS   H2   H  N N 258 
LYS   HA   H  N N 259 
LYS   HB2  H  N N 260 
LYS   HB3  H  N N 261 
LYS   HG2  H  N N 262 
LYS   HG3  H  N N 263 
LYS   HD2  H  N N 264 
LYS   HD3  H  N N 265 
LYS   HE2  H  N N 266 
LYS   HE3  H  N N 267 
LYS   HZ1  H  N N 268 
LYS   HZ2  H  N N 269 
LYS   HZ3  H  N N 270 
LYS   HXT  H  N N 271 
MET   N    N  N N 272 
MET   CA   C  N S 273 
MET   C    C  N N 274 
MET   O    O  N N 275 
MET   CB   C  N N 276 
MET   CG   C  N N 277 
MET   SD   S  N N 278 
MET   CE   C  N N 279 
MET   OXT  O  N N 280 
MET   H    H  N N 281 
MET   H2   H  N N 282 
MET   HA   H  N N 283 
MET   HB2  H  N N 284 
MET   HB3  H  N N 285 
MET   HG2  H  N N 286 
MET   HG3  H  N N 287 
MET   HE1  H  N N 288 
MET   HE2  H  N N 289 
MET   HE3  H  N N 290 
MET   HXT  H  N N 291 
PHE   N    N  N N 292 
PHE   CA   C  N S 293 
PHE   C    C  N N 294 
PHE   O    O  N N 295 
PHE   CB   C  N N 296 
PHE   CG   C  Y N 297 
PHE   CD1  C  Y N 298 
PHE   CD2  C  Y N 299 
PHE   CE1  C  Y N 300 
PHE   CE2  C  Y N 301 
PHE   CZ   C  Y N 302 
PHE   OXT  O  N N 303 
PHE   H    H  N N 304 
PHE   H2   H  N N 305 
PHE   HA   H  N N 306 
PHE   HB2  H  N N 307 
PHE   HB3  H  N N 308 
PHE   HD1  H  N N 309 
PHE   HD2  H  N N 310 
PHE   HE1  H  N N 311 
PHE   HE2  H  N N 312 
PHE   HZ   H  N N 313 
PHE   HXT  H  N N 314 
PRO   N    N  N N 315 
PRO   CA   C  N S 316 
PRO   C    C  N N 317 
PRO   O    O  N N 318 
PRO   CB   C  N N 319 
PRO   CG   C  N N 320 
PRO   CD   C  N N 321 
PRO   OXT  O  N N 322 
PRO   H    H  N N 323 
PRO   HA   H  N N 324 
PRO   HB2  H  N N 325 
PRO   HB3  H  N N 326 
PRO   HG2  H  N N 327 
PRO   HG3  H  N N 328 
PRO   HD2  H  N N 329 
PRO   HD3  H  N N 330 
PRO   HXT  H  N N 331 
SER   N    N  N N 332 
SER   CA   C  N S 333 
SER   C    C  N N 334 
SER   O    O  N N 335 
SER   CB   C  N N 336 
SER   OG   O  N N 337 
SER   OXT  O  N N 338 
SER   H    H  N N 339 
SER   H2   H  N N 340 
SER   HA   H  N N 341 
SER   HB2  H  N N 342 
SER   HB3  H  N N 343 
SER   HG   H  N N 344 
SER   HXT  H  N N 345 
SO4   S    S  N N 346 
SO4   O1   O  N N 347 
SO4   O2   O  N N 348 
SO4   O3   O  N N 349 
SO4   O4   O  N N 350 
THR   N    N  N N 351 
THR   CA   C  N S 352 
THR   C    C  N N 353 
THR   O    O  N N 354 
THR   CB   C  N R 355 
THR   OG1  O  N N 356 
THR   CG2  C  N N 357 
THR   OXT  O  N N 358 
THR   H    H  N N 359 
THR   H2   H  N N 360 
THR   HA   H  N N 361 
THR   HB   H  N N 362 
THR   HG1  H  N N 363 
THR   HG21 H  N N 364 
THR   HG22 H  N N 365 
THR   HG23 H  N N 366 
THR   HXT  H  N N 367 
TRP   N    N  N N 368 
TRP   CA   C  N S 369 
TRP   C    C  N N 370 
TRP   O    O  N N 371 
TRP   CB   C  N N 372 
TRP   CG   C  Y N 373 
TRP   CD1  C  Y N 374 
TRP   CD2  C  Y N 375 
TRP   NE1  N  Y N 376 
TRP   CE2  C  Y N 377 
TRP   CE3  C  Y N 378 
TRP   CZ2  C  Y N 379 
TRP   CZ3  C  Y N 380 
TRP   CH2  C  Y N 381 
TRP   OXT  O  N N 382 
TRP   H    H  N N 383 
TRP   H2   H  N N 384 
TRP   HA   H  N N 385 
TRP   HB2  H  N N 386 
TRP   HB3  H  N N 387 
TRP   HD1  H  N N 388 
TRP   HE1  H  N N 389 
TRP   HE3  H  N N 390 
TRP   HZ2  H  N N 391 
TRP   HZ3  H  N N 392 
TRP   HH2  H  N N 393 
TRP   HXT  H  N N 394 
TYR   N    N  N N 395 
TYR   CA   C  N S 396 
TYR   C    C  N N 397 
TYR   O    O  N N 398 
TYR   CB   C  N N 399 
TYR   CG   C  Y N 400 
TYR   CD1  C  Y N 401 
TYR   CD2  C  Y N 402 
TYR   CE1  C  Y N 403 
TYR   CE2  C  Y N 404 
TYR   CZ   C  Y N 405 
TYR   OH   O  N N 406 
TYR   OXT  O  N N 407 
TYR   H    H  N N 408 
TYR   H2   H  N N 409 
TYR   HA   H  N N 410 
TYR   HB2  H  N N 411 
TYR   HB3  H  N N 412 
TYR   HD1  H  N N 413 
TYR   HD2  H  N N 414 
TYR   HE1  H  N N 415 
TYR   HE2  H  N N 416 
TYR   HH   H  N N 417 
TYR   HXT  H  N N 418 
VAL   N    N  N N 419 
VAL   CA   C  N S 420 
VAL   C    C  N N 421 
VAL   O    O  N N 422 
VAL   CB   C  N N 423 
VAL   CG1  C  N N 424 
VAL   CG2  C  N N 425 
VAL   OXT  O  N N 426 
VAL   H    H  N N 427 
VAL   H2   H  N N 428 
VAL   HA   H  N N 429 
VAL   HB   H  N N 430 
VAL   HG11 H  N N 431 
VAL   HG12 H  N N 432 
VAL   HG13 H  N N 433 
VAL   HG21 H  N N 434 
VAL   HG22 H  N N 435 
VAL   HG23 H  N N 436 
VAL   HXT  H  N N 437 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1AI3 CAE CAF  sing N N 1   
A1AI3 CAE CAD  sing N N 2   
A1AI3 CAF CAG  sing N N 3   
A1AI3 CAG CAH  sing N N 4   
A1AI3 OAO CAC  doub N N 5   
A1AI3 OXT C    doub N N 6   
A1AI3 CAI CAH  sing N N 7   
A1AI3 CAI CAJ  sing N N 8   
A1AI3 CAD CAC  sing N N 9   
A1AI3 CAC N    sing N N 10  
A1AI3 C   O    sing N N 11  
A1AI3 C   CA   sing N N 12  
A1AI3 N   CA   sing N N 13  
A1AI3 CA  CB   sing N N 14  
A1AI3 OAQ CAL  sing N N 15  
A1AI3 CB  CAL  sing N N 16  
A1AI3 CAJ H1   sing N N 17  
A1AI3 CAJ H2   sing N N 18  
A1AI3 CAJ H3   sing N N 19  
A1AI3 CAI H4   sing N N 20  
A1AI3 CAI H5   sing N N 21  
A1AI3 CAH H6   sing N N 22  
A1AI3 CAH H7   sing N N 23  
A1AI3 CAG H8   sing N N 24  
A1AI3 CAG H9   sing N N 25  
A1AI3 CAF H10  sing N N 26  
A1AI3 CAF H11  sing N N 27  
A1AI3 CAE H12  sing N N 28  
A1AI3 CAE H13  sing N N 29  
A1AI3 CAD H14  sing N N 30  
A1AI3 CAD H15  sing N N 31  
A1AI3 N   H16  sing N N 32  
A1AI3 CA  H17  sing N N 33  
A1AI3 O   H18  sing N N 34  
A1AI3 CB  H19  sing N N 35  
A1AI3 CB  H20  sing N N 36  
A1AI3 CAL H21  sing N N 37  
A1AI3 CAL H22  sing N N 38  
A1AI3 OAQ H23  sing N N 39  
ALA   N   CA   sing N N 40  
ALA   N   H    sing N N 41  
ALA   N   H2   sing N N 42  
ALA   CA  C    sing N N 43  
ALA   CA  CB   sing N N 44  
ALA   CA  HA   sing N N 45  
ALA   C   O    doub N N 46  
ALA   C   OXT  sing N N 47  
ALA   CB  HB1  sing N N 48  
ALA   CB  HB2  sing N N 49  
ALA   CB  HB3  sing N N 50  
ALA   OXT HXT  sing N N 51  
ARG   N   CA   sing N N 52  
ARG   N   H    sing N N 53  
ARG   N   H2   sing N N 54  
ARG   CA  C    sing N N 55  
ARG   CA  CB   sing N N 56  
ARG   CA  HA   sing N N 57  
ARG   C   O    doub N N 58  
ARG   C   OXT  sing N N 59  
ARG   CB  CG   sing N N 60  
ARG   CB  HB2  sing N N 61  
ARG   CB  HB3  sing N N 62  
ARG   CG  CD   sing N N 63  
ARG   CG  HG2  sing N N 64  
ARG   CG  HG3  sing N N 65  
ARG   CD  NE   sing N N 66  
ARG   CD  HD2  sing N N 67  
ARG   CD  HD3  sing N N 68  
ARG   NE  CZ   sing N N 69  
ARG   NE  HE   sing N N 70  
ARG   CZ  NH1  sing N N 71  
ARG   CZ  NH2  doub N N 72  
ARG   NH1 HH11 sing N N 73  
ARG   NH1 HH12 sing N N 74  
ARG   NH2 HH21 sing N N 75  
ARG   NH2 HH22 sing N N 76  
ARG   OXT HXT  sing N N 77  
ASN   N   CA   sing N N 78  
ASN   N   H    sing N N 79  
ASN   N   H2   sing N N 80  
ASN   CA  C    sing N N 81  
ASN   CA  CB   sing N N 82  
ASN   CA  HA   sing N N 83  
ASN   C   O    doub N N 84  
ASN   C   OXT  sing N N 85  
ASN   CB  CG   sing N N 86  
ASN   CB  HB2  sing N N 87  
ASN   CB  HB3  sing N N 88  
ASN   CG  OD1  doub N N 89  
ASN   CG  ND2  sing N N 90  
ASN   ND2 HD21 sing N N 91  
ASN   ND2 HD22 sing N N 92  
ASN   OXT HXT  sing N N 93  
ASP   N   CA   sing N N 94  
ASP   N   H    sing N N 95  
ASP   N   H2   sing N N 96  
ASP   CA  C    sing N N 97  
ASP   CA  CB   sing N N 98  
ASP   CA  HA   sing N N 99  
ASP   C   O    doub N N 100 
ASP   C   OXT  sing N N 101 
ASP   CB  CG   sing N N 102 
ASP   CB  HB2  sing N N 103 
ASP   CB  HB3  sing N N 104 
ASP   CG  OD1  doub N N 105 
ASP   CG  OD2  sing N N 106 
ASP   OD2 HD2  sing N N 107 
ASP   OXT HXT  sing N N 108 
CYS   N   CA   sing N N 109 
CYS   N   H    sing N N 110 
CYS   N   H2   sing N N 111 
CYS   CA  C    sing N N 112 
CYS   CA  CB   sing N N 113 
CYS   CA  HA   sing N N 114 
CYS   C   O    doub N N 115 
CYS   C   OXT  sing N N 116 
CYS   CB  SG   sing N N 117 
CYS   CB  HB2  sing N N 118 
CYS   CB  HB3  sing N N 119 
CYS   SG  HG   sing N N 120 
CYS   OXT HXT  sing N N 121 
GLN   N   CA   sing N N 122 
GLN   N   H    sing N N 123 
GLN   N   H2   sing N N 124 
GLN   CA  C    sing N N 125 
GLN   CA  CB   sing N N 126 
GLN   CA  HA   sing N N 127 
GLN   C   O    doub N N 128 
GLN   C   OXT  sing N N 129 
GLN   CB  CG   sing N N 130 
GLN   CB  HB2  sing N N 131 
GLN   CB  HB3  sing N N 132 
GLN   CG  CD   sing N N 133 
GLN   CG  HG2  sing N N 134 
GLN   CG  HG3  sing N N 135 
GLN   CD  OE1  doub N N 136 
GLN   CD  NE2  sing N N 137 
GLN   NE2 HE21 sing N N 138 
GLN   NE2 HE22 sing N N 139 
GLN   OXT HXT  sing N N 140 
GLU   N   CA   sing N N 141 
GLU   N   H    sing N N 142 
GLU   N   H2   sing N N 143 
GLU   CA  C    sing N N 144 
GLU   CA  CB   sing N N 145 
GLU   CA  HA   sing N N 146 
GLU   C   O    doub N N 147 
GLU   C   OXT  sing N N 148 
GLU   CB  CG   sing N N 149 
GLU   CB  HB2  sing N N 150 
GLU   CB  HB3  sing N N 151 
GLU   CG  CD   sing N N 152 
GLU   CG  HG2  sing N N 153 
GLU   CG  HG3  sing N N 154 
GLU   CD  OE1  doub N N 155 
GLU   CD  OE2  sing N N 156 
GLU   OE2 HE2  sing N N 157 
GLU   OXT HXT  sing N N 158 
GLY   N   CA   sing N N 159 
GLY   N   H    sing N N 160 
GLY   N   H2   sing N N 161 
GLY   CA  C    sing N N 162 
GLY   CA  HA2  sing N N 163 
GLY   CA  HA3  sing N N 164 
GLY   C   O    doub N N 165 
GLY   C   OXT  sing N N 166 
GLY   OXT HXT  sing N N 167 
HIS   N   CA   sing N N 168 
HIS   N   H    sing N N 169 
HIS   N   H2   sing N N 170 
HIS   CA  C    sing N N 171 
HIS   CA  CB   sing N N 172 
HIS   CA  HA   sing N N 173 
HIS   C   O    doub N N 174 
HIS   C   OXT  sing N N 175 
HIS   CB  CG   sing N N 176 
HIS   CB  HB2  sing N N 177 
HIS   CB  HB3  sing N N 178 
HIS   CG  ND1  sing Y N 179 
HIS   CG  CD2  doub Y N 180 
HIS   ND1 CE1  doub Y N 181 
HIS   ND1 HD1  sing N N 182 
HIS   CD2 NE2  sing Y N 183 
HIS   CD2 HD2  sing N N 184 
HIS   CE1 NE2  sing Y N 185 
HIS   CE1 HE1  sing N N 186 
HIS   NE2 HE2  sing N N 187 
HIS   OXT HXT  sing N N 188 
HOH   O   H1   sing N N 189 
HOH   O   H2   sing N N 190 
ILE   N   CA   sing N N 191 
ILE   N   H    sing N N 192 
ILE   N   H2   sing N N 193 
ILE   CA  C    sing N N 194 
ILE   CA  CB   sing N N 195 
ILE   CA  HA   sing N N 196 
ILE   C   O    doub N N 197 
ILE   C   OXT  sing N N 198 
ILE   CB  CG1  sing N N 199 
ILE   CB  CG2  sing N N 200 
ILE   CB  HB   sing N N 201 
ILE   CG1 CD1  sing N N 202 
ILE   CG1 HG12 sing N N 203 
ILE   CG1 HG13 sing N N 204 
ILE   CG2 HG21 sing N N 205 
ILE   CG2 HG22 sing N N 206 
ILE   CG2 HG23 sing N N 207 
ILE   CD1 HD11 sing N N 208 
ILE   CD1 HD12 sing N N 209 
ILE   CD1 HD13 sing N N 210 
ILE   OXT HXT  sing N N 211 
LEU   N   CA   sing N N 212 
LEU   N   H    sing N N 213 
LEU   N   H2   sing N N 214 
LEU   CA  C    sing N N 215 
LEU   CA  CB   sing N N 216 
LEU   CA  HA   sing N N 217 
LEU   C   O    doub N N 218 
LEU   C   OXT  sing N N 219 
LEU   CB  CG   sing N N 220 
LEU   CB  HB2  sing N N 221 
LEU   CB  HB3  sing N N 222 
LEU   CG  CD1  sing N N 223 
LEU   CG  CD2  sing N N 224 
LEU   CG  HG   sing N N 225 
LEU   CD1 HD11 sing N N 226 
LEU   CD1 HD12 sing N N 227 
LEU   CD1 HD13 sing N N 228 
LEU   CD2 HD21 sing N N 229 
LEU   CD2 HD22 sing N N 230 
LEU   CD2 HD23 sing N N 231 
LEU   OXT HXT  sing N N 232 
LYS   N   CA   sing N N 233 
LYS   N   H    sing N N 234 
LYS   N   H2   sing N N 235 
LYS   CA  C    sing N N 236 
LYS   CA  CB   sing N N 237 
LYS   CA  HA   sing N N 238 
LYS   C   O    doub N N 239 
LYS   C   OXT  sing N N 240 
LYS   CB  CG   sing N N 241 
LYS   CB  HB2  sing N N 242 
LYS   CB  HB3  sing N N 243 
LYS   CG  CD   sing N N 244 
LYS   CG  HG2  sing N N 245 
LYS   CG  HG3  sing N N 246 
LYS   CD  CE   sing N N 247 
LYS   CD  HD2  sing N N 248 
LYS   CD  HD3  sing N N 249 
LYS   CE  NZ   sing N N 250 
LYS   CE  HE2  sing N N 251 
LYS   CE  HE3  sing N N 252 
LYS   NZ  HZ1  sing N N 253 
LYS   NZ  HZ2  sing N N 254 
LYS   NZ  HZ3  sing N N 255 
LYS   OXT HXT  sing N N 256 
MET   N   CA   sing N N 257 
MET   N   H    sing N N 258 
MET   N   H2   sing N N 259 
MET   CA  C    sing N N 260 
MET   CA  CB   sing N N 261 
MET   CA  HA   sing N N 262 
MET   C   O    doub N N 263 
MET   C   OXT  sing N N 264 
MET   CB  CG   sing N N 265 
MET   CB  HB2  sing N N 266 
MET   CB  HB3  sing N N 267 
MET   CG  SD   sing N N 268 
MET   CG  HG2  sing N N 269 
MET   CG  HG3  sing N N 270 
MET   SD  CE   sing N N 271 
MET   CE  HE1  sing N N 272 
MET   CE  HE2  sing N N 273 
MET   CE  HE3  sing N N 274 
MET   OXT HXT  sing N N 275 
PHE   N   CA   sing N N 276 
PHE   N   H    sing N N 277 
PHE   N   H2   sing N N 278 
PHE   CA  C    sing N N 279 
PHE   CA  CB   sing N N 280 
PHE   CA  HA   sing N N 281 
PHE   C   O    doub N N 282 
PHE   C   OXT  sing N N 283 
PHE   CB  CG   sing N N 284 
PHE   CB  HB2  sing N N 285 
PHE   CB  HB3  sing N N 286 
PHE   CG  CD1  doub Y N 287 
PHE   CG  CD2  sing Y N 288 
PHE   CD1 CE1  sing Y N 289 
PHE   CD1 HD1  sing N N 290 
PHE   CD2 CE2  doub Y N 291 
PHE   CD2 HD2  sing N N 292 
PHE   CE1 CZ   doub Y N 293 
PHE   CE1 HE1  sing N N 294 
PHE   CE2 CZ   sing Y N 295 
PHE   CE2 HE2  sing N N 296 
PHE   CZ  HZ   sing N N 297 
PHE   OXT HXT  sing N N 298 
PRO   N   CA   sing N N 299 
PRO   N   CD   sing N N 300 
PRO   N   H    sing N N 301 
PRO   CA  C    sing N N 302 
PRO   CA  CB   sing N N 303 
PRO   CA  HA   sing N N 304 
PRO   C   O    doub N N 305 
PRO   C   OXT  sing N N 306 
PRO   CB  CG   sing N N 307 
PRO   CB  HB2  sing N N 308 
PRO   CB  HB3  sing N N 309 
PRO   CG  CD   sing N N 310 
PRO   CG  HG2  sing N N 311 
PRO   CG  HG3  sing N N 312 
PRO   CD  HD2  sing N N 313 
PRO   CD  HD3  sing N N 314 
PRO   OXT HXT  sing N N 315 
SER   N   CA   sing N N 316 
SER   N   H    sing N N 317 
SER   N   H2   sing N N 318 
SER   CA  C    sing N N 319 
SER   CA  CB   sing N N 320 
SER   CA  HA   sing N N 321 
SER   C   O    doub N N 322 
SER   C   OXT  sing N N 323 
SER   CB  OG   sing N N 324 
SER   CB  HB2  sing N N 325 
SER   CB  HB3  sing N N 326 
SER   OG  HG   sing N N 327 
SER   OXT HXT  sing N N 328 
SO4   S   O1   doub N N 329 
SO4   S   O2   doub N N 330 
SO4   S   O3   sing N N 331 
SO4   S   O4   sing N N 332 
THR   N   CA   sing N N 333 
THR   N   H    sing N N 334 
THR   N   H2   sing N N 335 
THR   CA  C    sing N N 336 
THR   CA  CB   sing N N 337 
THR   CA  HA   sing N N 338 
THR   C   O    doub N N 339 
THR   C   OXT  sing N N 340 
THR   CB  OG1  sing N N 341 
THR   CB  CG2  sing N N 342 
THR   CB  HB   sing N N 343 
THR   OG1 HG1  sing N N 344 
THR   CG2 HG21 sing N N 345 
THR   CG2 HG22 sing N N 346 
THR   CG2 HG23 sing N N 347 
THR   OXT HXT  sing N N 348 
TRP   N   CA   sing N N 349 
TRP   N   H    sing N N 350 
TRP   N   H2   sing N N 351 
TRP   CA  C    sing N N 352 
TRP   CA  CB   sing N N 353 
TRP   CA  HA   sing N N 354 
TRP   C   O    doub N N 355 
TRP   C   OXT  sing N N 356 
TRP   CB  CG   sing N N 357 
TRP   CB  HB2  sing N N 358 
TRP   CB  HB3  sing N N 359 
TRP   CG  CD1  doub Y N 360 
TRP   CG  CD2  sing Y N 361 
TRP   CD1 NE1  sing Y N 362 
TRP   CD1 HD1  sing N N 363 
TRP   CD2 CE2  doub Y N 364 
TRP   CD2 CE3  sing Y N 365 
TRP   NE1 CE2  sing Y N 366 
TRP   NE1 HE1  sing N N 367 
TRP   CE2 CZ2  sing Y N 368 
TRP   CE3 CZ3  doub Y N 369 
TRP   CE3 HE3  sing N N 370 
TRP   CZ2 CH2  doub Y N 371 
TRP   CZ2 HZ2  sing N N 372 
TRP   CZ3 CH2  sing Y N 373 
TRP   CZ3 HZ3  sing N N 374 
TRP   CH2 HH2  sing N N 375 
TRP   OXT HXT  sing N N 376 
TYR   N   CA   sing N N 377 
TYR   N   H    sing N N 378 
TYR   N   H2   sing N N 379 
TYR   CA  C    sing N N 380 
TYR   CA  CB   sing N N 381 
TYR   CA  HA   sing N N 382 
TYR   C   O    doub N N 383 
TYR   C   OXT  sing N N 384 
TYR   CB  CG   sing N N 385 
TYR   CB  HB2  sing N N 386 
TYR   CB  HB3  sing N N 387 
TYR   CG  CD1  doub Y N 388 
TYR   CG  CD2  sing Y N 389 
TYR   CD1 CE1  sing Y N 390 
TYR   CD1 HD1  sing N N 391 
TYR   CD2 CE2  doub Y N 392 
TYR   CD2 HD2  sing N N 393 
TYR   CE1 CZ   doub Y N 394 
TYR   CE1 HE1  sing N N 395 
TYR   CE2 CZ   sing Y N 396 
TYR   CE2 HE2  sing N N 397 
TYR   CZ  OH   sing N N 398 
TYR   OH  HH   sing N N 399 
TYR   OXT HXT  sing N N 400 
VAL   N   CA   sing N N 401 
VAL   N   H    sing N N 402 
VAL   N   H2   sing N N 403 
VAL   CA  C    sing N N 404 
VAL   CA  CB   sing N N 405 
VAL   CA  HA   sing N N 406 
VAL   C   O    doub N N 407 
VAL   C   OXT  sing N N 408 
VAL   CB  CG1  sing N N 409 
VAL   CB  CG2  sing N N 410 
VAL   CB  HB   sing N N 411 
VAL   CG1 HG11 sing N N 412 
VAL   CG1 HG12 sing N N 413 
VAL   CG1 HG13 sing N N 414 
VAL   CG2 HG21 sing N N 415 
VAL   CG2 HG22 sing N N 416 
VAL   CG2 HG23 sing N N 417 
VAL   OXT HXT  sing N N 418 
# 
_pdbx_audit_support.funding_organization   
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           R35GM133487 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6n9i 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9B2O 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.006197 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.003069 
_atom_sites.fract_transf_matrix[2][1]   -0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.009107 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   -0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.011461 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
CO 
FE 
N  
O  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . ALA   A 1 22  ? 34.580  -6.552  -14.180 1.00 64.42  ? 8   ALA   X N   1 
ATOM   2    C  CA  . ALA   A 1 22  ? 34.222  -5.265  -13.420 1.00 69.38  ? 8   ALA   X CA  1 
ATOM   3    C  C   . ALA   A 1 22  ? 35.111  -5.135  -12.175 1.00 64.20  ? 8   ALA   X C   1 
ATOM   4    O  O   . ALA   A 1 22  ? 35.266  -6.167  -11.470 1.00 58.75  ? 8   ALA   X O   1 
ATOM   5    C  CB  . ALA   A 1 22  ? 32.751  -5.246  -13.032 1.00 67.44  ? 8   ALA   X CB  1 
ATOM   6    N  N   . ARG   A 1 23  ? 35.626  -3.917  -11.904 1.00 64.27  ? 9   ARG   X N   1 
ATOM   7    C  CA  . ARG   A 1 23  ? 36.502  -3.555  -10.746 1.00 56.27  ? 9   ARG   X CA  1 
ATOM   8    C  C   . ARG   A 1 23  ? 35.826  -2.448  -9.939  1.00 50.35  ? 9   ARG   X C   1 
ATOM   9    O  O   . ARG   A 1 23  ? 36.260  -1.278  -9.909  1.00 43.00  ? 9   ARG   X O   1 
ATOM   10   C  CB  . ARG   A 1 23  ? 37.895  -3.072  -11.179 1.00 61.57  ? 9   ARG   X CB  1 
ATOM   11   C  CG  . ARG   A 1 23  ? 38.753  -4.067  -11.955 1.00 68.39  ? 9   ARG   X CG  1 
ATOM   12   C  CD  . ARG   A 1 23  ? 38.639  -5.493  -11.458 1.00 86.03  ? 9   ARG   X CD  1 
ATOM   13   N  NE  . ARG   A 1 23  ? 39.880  -6.281  -11.466 1.00 103.16 ? 9   ARG   X NE  1 
ATOM   14   C  CZ  . ARG   A 1 23  ? 39.957  -7.610  -11.654 1.00 97.88  ? 9   ARG   X CZ  1 
ATOM   15   N  NH1 . ARG   A 1 23  ? 38.877  -8.335  -11.916 1.00 100.28 ? 9   ARG   X NH1 1 
ATOM   16   N  NH2 . ARG   A 1 23  ? 41.131  -8.213  -11.607 1.00 101.04 ? 9   ARG   X NH2 1 
ATOM   17   N  N   . PRO   A 1 24  ? 34.739  -2.794  -9.224  1.00 47.02  ? 10  PRO   X N   1 
ATOM   18   C  CA  . PRO   A 1 24  ? 34.050  -1.826  -8.384  1.00 41.50  ? 10  PRO   X CA  1 
ATOM   19   C  C   . PRO   A 1 24  ? 34.848  -1.405  -7.158  1.00 41.59  ? 10  PRO   X C   1 
ATOM   20   O  O   . PRO   A 1 24  ? 35.741  -2.117  -6.728  1.00 43.60  ? 10  PRO   X O   1 
ATOM   21   C  CB  . PRO   A 1 24  ? 32.784  -2.535  -7.872  1.00 45.72  ? 10  PRO   X CB  1 
ATOM   22   C  CG  . PRO   A 1 24  ? 32.820  -3.938  -8.441  1.00 50.22  ? 10  PRO   X CG  1 
ATOM   23   C  CD  . PRO   A 1 24  ? 34.107  -4.126  -9.207  1.00 49.70  ? 10  PRO   X CD  1 
ATOM   24   N  N   . LYS   A 1 25  ? 34.435  -0.291  -6.582  1.00 38.52  ? 11  LYS   X N   1 
ATOM   25   C  CA  . LYS   A 1 25  ? 34.873  0.149   -5.245  1.00 38.86  ? 11  LYS   X CA  1 
ATOM   26   C  C   . LYS   A 1 25  ? 33.662  0.319   -4.322  1.00 37.13  ? 11  LYS   X C   1 
ATOM   27   O  O   . LYS   A 1 25  ? 32.731  1.055   -4.664  1.00 37.46  ? 11  LYS   X O   1 
ATOM   28   C  CB  . LYS   A 1 25  ? 35.625  1.478   -5.357  1.00 43.92  ? 11  LYS   X CB  1 
ATOM   29   C  CG  . LYS   A 1 25  ? 36.989  1.425   -6.038  1.00 42.02  ? 11  LYS   X CG  1 
ATOM   30   C  CD  . LYS   A 1 25  ? 37.419  2.851   -6.335  1.00 51.71  ? 11  LYS   X CD  1 
ATOM   31   C  CE  . LYS   A 1 25  ? 38.895  3.000   -6.596  1.00 51.17  ? 11  LYS   X CE  1 
ATOM   32   N  NZ  . LYS   A 1 25  ? 39.284  2.180   -7.750  1.00 52.96  ? 11  LYS   X NZ  1 
ATOM   33   N  N   . LEU   A 1 26  ? 33.696  -0.325  -3.167  1.00 38.16  ? 12  LEU   X N   1 
ATOM   34   C  CA  . LEU   A 1 26  ? 32.599  -0.284  -2.173  1.00 35.32  ? 12  LEU   X CA  1 
ATOM   35   C  C   . LEU   A 1 26  ? 33.050  0.568   -0.984  1.00 33.12  ? 12  LEU   X C   1 
ATOM   36   O  O   . LEU   A 1 26  ? 34.144  0.329   -0.465  1.00 34.99  ? 12  LEU   X O   1 
ATOM   37   C  CB  . LEU   A 1 26  ? 32.220  -1.715  -1.773  1.00 36.50  ? 12  LEU   X CB  1 
ATOM   38   C  CG  . LEU   A 1 26  ? 31.083  -1.875  -0.771  1.00 36.44  ? 12  LEU   X CG  1 
ATOM   39   C  CD1 . LEU   A 1 26  ? 30.412  -3.236  -0.940  1.00 38.71  ? 12  LEU   X CD1 1 
ATOM   40   C  CD2 . LEU   A 1 26  ? 31.564  -1.718  0.653   1.00 36.69  ? 12  LEU   X CD2 1 
ATOM   41   N  N   . TYR   A 1 27  ? 32.236  1.552   -0.631  1.00 32.80  ? 13  TYR   X N   1 
ATOM   42   C  CA  . TYR   A 1 27  ? 32.498  2.531   0.445   1.00 33.66  ? 13  TYR   X CA  1 
ATOM   43   C  C   . TYR   A 1 27  ? 31.480  2.359   1.565   1.00 38.07  ? 13  TYR   X C   1 
ATOM   44   O  O   . TYR   A 1 27  ? 30.267  2.310   1.279   1.00 37.70  ? 13  TYR   X O   1 
ATOM   45   C  CB  . TYR   A 1 27  ? 32.336  3.959   -0.049  1.00 33.15  ? 13  TYR   X CB  1 
ATOM   46   C  CG  . TYR   A 1 27  ? 33.250  4.336   -1.173  1.00 39.23  ? 13  TYR   X CG  1 
ATOM   47   C  CD1 . TYR   A 1 27  ? 32.967  3.997   -2.492  1.00 40.30  ? 13  TYR   X CD1 1 
ATOM   48   C  CD2 . TYR   A 1 27  ? 34.406  5.061   -0.916  1.00 39.36  ? 13  TYR   X CD2 1 
ATOM   49   C  CE1 . TYR   A 1 27  ? 33.817  4.368   -3.532  1.00 38.03  ? 13  TYR   X CE1 1 
ATOM   50   C  CE2 . TYR   A 1 27  ? 35.256  5.428   -1.940  1.00 37.37  ? 13  TYR   X CE2 1 
ATOM   51   C  CZ  . TYR   A 1 27  ? 34.937  5.125   -3.249  1.00 38.44  ? 13  TYR   X CZ  1 
ATOM   52   O  OH  . TYR   A 1 27  ? 35.823  5.457   -4.220  1.00 44.83  ? 13  TYR   X OH  1 
ATOM   53   N  N   . VAL   A 1 28  ? 31.957  2.368   2.793   1.00 35.59  ? 14  VAL   X N   1 
ATOM   54   C  CA  . VAL   A 1 28  ? 31.131  2.445   4.026   1.00 35.05  ? 14  VAL   X CA  1 
ATOM   55   C  C   . VAL   A 1 28  ? 31.091  3.901   4.466   1.00 40.09  ? 14  VAL   X C   1 
ATOM   56   O  O   . VAL   A 1 28  ? 32.162  4.435   4.773   1.00 39.18  ? 14  VAL   X O   1 
ATOM   57   C  CB  . VAL   A 1 28  ? 31.727  1.538   5.101   1.00 36.51  ? 14  VAL   X CB  1 
ATOM   58   C  CG1 . VAL   A 1 28  ? 30.991  1.671   6.432   1.00 38.08  ? 14  VAL   X CG1 1 
ATOM   59   C  CG2 . VAL   A 1 28  ? 31.721  0.089   4.622   1.00 41.10  ? 14  VAL   X CG2 1 
ATOM   60   N  N   . MET   A 1 29  ? 29.899  4.494   4.519   1.00 35.21  ? 15  MET   X N   1 
ATOM   61   C  CA  . MET   A 1 29  ? 29.729  5.898   4.926   1.00 36.46  ? 15  MET   X CA  1 
ATOM   62   C  C   . MET   A 1 29  ? 29.123  5.975   6.326   1.00 41.14  ? 15  MET   X C   1 
ATOM   63   O  O   . MET   A 1 29  ? 28.057  5.389   6.593   1.00 38.96  ? 15  MET   X O   1 
ATOM   64   C  CB  . MET   A 1 29  ? 28.882  6.638   3.893   1.00 40.05  ? 15  MET   X CB  1 
ATOM   65   C  CG  . MET   A 1 29  ? 29.572  6.729   2.536   1.00 37.70  ? 15  MET   X CG  1 
ATOM   66   S  SD  . MET   A 1 29  ? 28.515  7.463   1.275   1.00 39.43  ? 15  MET   X SD  1 
ATOM   67   C  CE  . MET   A 1 29  ? 27.397  6.062   1.023   1.00 41.71  ? 15  MET   X CE  1 
ATOM   68   N  N   . ASP   A 1 30  ? 29.809  6.679   7.216   1.00 36.45  ? 16  ASP   X N   1 
ATOM   69   C  CA  . ASP   A 1 30  ? 29.394  6.852   8.626   1.00 40.57  ? 16  ASP   X CA  1 
ATOM   70   C  C   . ASP   A 1 30  ? 28.313  7.944   8.675   1.00 43.02  ? 16  ASP   X C   1 
ATOM   71   O  O   . ASP   A 1 30  ? 28.633  9.125   8.396   1.00 38.23  ? 16  ASP   X O   1 
ATOM   72   C  CB  . ASP   A 1 30  ? 30.644  7.145   9.443   1.00 43.45  ? 16  ASP   X CB  1 
ATOM   73   C  CG  . ASP   A 1 30  ? 30.430  7.257   10.935  1.00 49.04  ? 16  ASP   X CG  1 
ATOM   74   O  OD1 . ASP   A 1 30  ? 29.289  7.532   11.344  1.00 42.54  ? 16  ASP   X OD1 1 
ATOM   75   O  OD2 . ASP   A 1 30  ? 31.425  7.052   11.670  1.00 48.33  ? 16  ASP   X OD2 1 
ATOM   76   N  N   . ASN   A 1 31  ? 27.067  7.582   9.039   1.00 38.24  ? 17  ASN   X N   1 
ATOM   77   C  CA  . ASN   A 1 31  ? 25.926  8.536   9.064   1.00 36.88  ? 17  ASN   X CA  1 
ATOM   78   C  C   . ASN   A 1 31  ? 25.496  8.796   10.504  1.00 40.74  ? 17  ASN   X C   1 
ATOM   79   O  O   . ASN   A 1 31  ? 24.325  9.215   10.726  1.00 42.62  ? 17  ASN   X O   1 
ATOM   80   C  CB  . ASN   A 1 31  ? 24.765  8.090   8.168   1.00 38.47  ? 17  ASN   X CB  1 
ATOM   81   C  CG  . ASN   A 1 31  ? 25.196  7.867   6.747   1.00 40.29  ? 17  ASN   X CG  1 
ATOM   82   O  OD1 . ASN   A 1 31  ? 25.013  6.787   6.195   1.00 39.59  ? 17  ASN   X OD1 1 
ATOM   83   N  ND2 . ASN   A 1 31  ? 25.800  8.884   6.154   1.00 43.78  ? 17  ASN   X ND2 1 
ATOM   84   N  N   . GLY   A 1 32  ? 26.415  8.659   11.448  1.00 38.89  ? 18  GLY   X N   1 
ATOM   85   C  CA  . GLY   A 1 32  ? 26.192  9.085   12.842  1.00 37.91  ? 18  GLY   X CA  1 
ATOM   86   C  C   . GLY   A 1 32  ? 25.753  7.940   13.721  1.00 38.78  ? 18  GLY   X C   1 
ATOM   87   O  O   . GLY   A 1 32  ? 26.025  6.792   13.363  1.00 39.07  ? 18  GLY   X O   1 
ATOM   88   N  N   . ARG   A 1 33  ? 25.156  8.268   14.857  1.00 36.16  ? 19  ARG   X N   1 
ATOM   89   C  CA  . ARG   A 1 33  ? 24.976  7.354   16.015  1.00 42.08  ? 19  ARG   X CA  1 
ATOM   90   C  C   . ARG   A 1 33  ? 23.550  7.527   16.543  1.00 40.34  ? 19  ARG   X C   1 
ATOM   91   O  O   . ARG   A 1 33  ? 23.021  8.663   16.538  1.00 41.76  ? 19  ARG   X O   1 
ATOM   92   C  CB  . ARG   A 1 33  ? 25.978  7.669   17.131  1.00 44.89  ? 19  ARG   X CB  1 
ATOM   93   C  CG  . ARG   A 1 33  ? 27.443  7.541   16.744  1.00 44.89  ? 19  ARG   X CG  1 
ATOM   94   C  CD  . ARG   A 1 33  ? 27.924  6.108   16.620  1.00 47.70  ? 19  ARG   X CD  1 
ATOM   95   N  NE  . ARG   A 1 33  ? 29.294  6.097   16.100  1.00 47.82  ? 19  ARG   X NE  1 
ATOM   96   C  CZ  . ARG   A 1 33  ? 29.629  6.277   14.819  1.00 51.10  ? 19  ARG   X CZ  1 
ATOM   97   N  NH1 . ARG   A 1 33  ? 28.701  6.466   13.887  1.00 48.72  ? 19  ARG   X NH1 1 
ATOM   98   N  NH2 . ARG   A 1 33  ? 30.906  6.273   14.463  1.00 49.28  ? 19  ARG   X NH2 1 
ATOM   99   N  N   . MET   A 1 34  ? 22.922  6.416   16.903  1.00 42.62  ? 20  MET   X N   1 
ATOM   100  C  CA  . MET   A 1 34  ? 21.601  6.397   17.558  1.00 40.00  ? 20  MET   X CA  1 
ATOM   101  C  C   . MET   A 1 34  ? 21.767  5.678   18.888  1.00 36.55  ? 20  MET   X C   1 
ATOM   102  O  O   . MET   A 1 34  ? 22.695  4.848   19.043  1.00 40.10  ? 20  MET   X O   1 
ATOM   103  C  CB  . MET   A 1 34  ? 20.591  5.678   16.663  1.00 43.68  ? 20  MET   X CB  1 
ATOM   104  C  CG  . MET   A 1 34  ? 19.167  5.662   17.178  1.00 50.30  ? 20  MET   X CG  1 
ATOM   105  S  SD  . MET   A 1 34  ? 17.969  5.062   15.893  1.00 47.62  ? 20  MET   X SD  1 
ATOM   106  C  CE  . MET   A 1 34  ? 17.925  6.442   14.760  1.00 38.71  ? 20  MET   X CE  1 
ATOM   107  N  N   . ARG   A 1 35  ? 20.859  5.972   19.800  1.00 39.55  ? 21  ARG   X N   1 
ATOM   108  C  CA  . ARG   A 1 35  ? 20.720  5.259   21.079  1.00 41.97  ? 21  ARG   X CA  1 
ATOM   109  C  C   . ARG   A 1 35  ? 19.267  4.802   21.218  1.00 39.40  ? 21  ARG   X C   1 
ATOM   110  O  O   . ARG   A 1 35  ? 18.336  5.523   20.764  1.00 41.61  ? 21  ARG   X O   1 
ATOM   111  C  CB  . ARG   A 1 35  ? 21.131  6.191   22.219  1.00 45.70  ? 21  ARG   X CB  1 
ATOM   112  C  CG  . ARG   A 1 35  ? 22.617  6.541   22.197  1.00 51.69  ? 21  ARG   X CG  1 
ATOM   113  C  CD  . ARG   A 1 35  ? 23.011  7.420   23.383  1.00 51.81  ? 21  ARG   X CD  1 
ATOM   114  N  NE  . ARG   A 1 35  ? 22.363  8.734   23.326  1.00 59.38  ? 21  ARG   X NE  1 
ATOM   115  C  CZ  . ARG   A 1 35  ? 22.114  9.513   24.403  1.00 63.45  ? 21  ARG   X CZ  1 
ATOM   116  N  NH1 . ARG   A 1 35  ? 22.461  9.129   25.629  1.00 62.50  ? 21  ARG   X NH1 1 
ATOM   117  N  NH2 . ARG   A 1 35  ? 21.515  10.671  24.249  1.00 56.95  ? 21  ARG   X NH2 1 
ATOM   118  N  N   . MET   A 1 36  ? 19.097  3.669   21.867  1.00 38.10  ? 22  MET   X N   1 
ATOM   119  C  CA  . MET   A 1 36  ? 17.759  3.209   22.281  1.00 36.56  ? 22  MET   X CA  1 
ATOM   120  C  C   . MET   A 1 36  ? 17.891  2.182   23.405  1.00 39.44  ? 22  MET   X C   1 
ATOM   121  O  O   . MET   A 1 36  ? 18.997  1.647   23.653  1.00 36.66  ? 22  MET   X O   1 
ATOM   122  C  CB  . MET   A 1 36  ? 17.049  2.625   21.050  1.00 37.83  ? 22  MET   X CB  1 
ATOM   123  C  CG  . MET   A 1 36  ? 17.629  1.297   20.558  1.00 37.97  ? 22  MET   X CG  1 
ATOM   124  S  SD  . MET   A 1 36  ? 16.836  0.806   19.003  1.00 42.58  ? 22  MET   X SD  1 
ATOM   125  C  CE  . MET   A 1 36  ? 17.743  -0.704  18.674  1.00 42.13  ? 22  MET   X CE  1 
ATOM   126  N  N   . ASP   A 1 37  ? 16.770  1.897   24.056  1.00 39.36  ? 23  ASP   X N   1 
ATOM   127  C  CA  . ASP   A 1 37  ? 16.646  0.798   25.039  1.00 37.20  ? 23  ASP   X CA  1 
ATOM   128  C  C   . ASP   A 1 37  ? 17.284  -0.438  24.435  1.00 34.99  ? 23  ASP   X C   1 
ATOM   129  O  O   . ASP   A 1 37  ? 16.915  -0.790  23.289  1.00 41.11  ? 23  ASP   X O   1 
ATOM   130  C  CB  . ASP   A 1 37  ? 15.170  0.626   25.388  1.00 38.11  ? 23  ASP   X CB  1 
ATOM   131  C  CG  . ASP   A 1 37  ? 14.854  -0.229  26.580  1.00 34.88  ? 23  ASP   X CG  1 
ATOM   132  O  OD1 . ASP   A 1 37  ? 15.567  -1.282  26.826  1.00 37.65  ? 23  ASP   X OD1 1 
ATOM   133  O  OD2 . ASP   A 1 37  ? 13.828  0.111   27.218  1.00 39.90  ? 23  ASP   X OD2 1 
ATOM   134  N  N   . LYS   A 1 38  ? 18.153  -1.126  25.168  1.00 35.24  ? 24  LYS   X N   1 
ATOM   135  C  CA  . LYS   A 1 38  ? 18.795  -2.354  24.651  1.00 41.23  ? 24  LYS   X CA  1 
ATOM   136  C  C   . LYS   A 1 38  ? 17.745  -3.458  24.426  1.00 42.03  ? 24  LYS   X C   1 
ATOM   137  O  O   . LYS   A 1 38  ? 18.031  -4.384  23.653  1.00 43.49  ? 24  LYS   X O   1 
ATOM   138  C  CB  . LYS   A 1 38  ? 19.837  -2.908  25.623  1.00 43.34  ? 24  LYS   X CB  1 
ATOM   139  C  CG  . LYS   A 1 38  ? 20.781  -3.950  25.016  1.00 49.24  ? 24  LYS   X CG  1 
ATOM   140  C  CD  . LYS   A 1 38  ? 21.789  -4.490  26.024  1.00 64.25  ? 24  LYS   X CD  1 
ATOM   141  C  CE  . LYS   A 1 38  ? 22.492  -5.775  25.617  1.00 65.69  ? 24  LYS   X CE  1 
ATOM   142  N  NZ  . LYS   A 1 38  ? 23.199  -5.629  24.333  1.00 61.66  ? 24  LYS   X NZ  1 
ATOM   143  N  N   . ASN   A 1 39  ? 16.618  -3.409  25.131  1.00 40.08  ? 25  ASN   X N   1 
ATOM   144  C  CA  . ASN   A 1 39  ? 15.505  -4.397  24.941  1.00 40.70  ? 25  ASN   X CA  1 
ATOM   145  C  C   . ASN   A 1 39  ? 14.947  -4.331  23.510  1.00 39.26  ? 25  ASN   X C   1 
ATOM   146  O  O   . ASN   A 1 39  ? 14.444  -5.346  23.062  1.00 39.38  ? 25  ASN   X O   1 
ATOM   147  C  CB  . ASN   A 1 39  ? 14.391  -4.254  25.977  1.00 40.21  ? 25  ASN   X CB  1 
ATOM   148  C  CG  . ASN   A 1 39  ? 14.775  -4.815  27.327  1.00 44.27  ? 25  ASN   X CG  1 
ATOM   149  O  OD1 . ASN   A 1 39  ? 14.606  -4.153  28.353  1.00 55.98  ? 25  ASN   X OD1 1 
ATOM   150  N  ND2 . ASN   A 1 39  ? 15.275  -6.029  27.338  1.00 37.52  ? 25  ASN   X ND2 1 
ATOM   151  N  N   . TRP   A 1 40  ? 15.004  -3.194  22.822  1.00 37.33  ? 26  TRP   X N   1 
ATOM   152  C  CA  . TRP   A 1 40  ? 14.673  -3.127  21.374  1.00 38.52  ? 26  TRP   X CA  1 
ATOM   153  C  C   . TRP   A 1 40  ? 15.648  -4.014  20.595  1.00 40.60  ? 26  TRP   X C   1 
ATOM   154  O  O   . TRP   A 1 40  ? 15.237  -4.573  19.558  1.00 39.15  ? 26  TRP   X O   1 
ATOM   155  C  CB  . TRP   A 1 40  ? 14.718  -1.720  20.783  1.00 35.81  ? 26  TRP   X CB  1 
ATOM   156  C  CG  . TRP   A 1 40  ? 13.753  -0.710  21.322  1.00 40.52  ? 26  TRP   X CG  1 
ATOM   157  C  CD1 . TRP   A 1 40  ? 14.083  0.466   21.931  1.00 44.49  ? 26  TRP   X CD1 1 
ATOM   158  C  CD2 . TRP   A 1 40  ? 12.327  -0.691  21.189  1.00 42.67  ? 26  TRP   X CD2 1 
ATOM   159  N  NE1 . TRP   A 1 40  ? 12.965  1.181   22.253  1.00 42.19  ? 26  TRP   X NE1 1 
ATOM   160  C  CE2 . TRP   A 1 40  ? 11.870  0.510   21.780  1.00 48.35  ? 26  TRP   X CE2 1 
ATOM   161  C  CE3 . TRP   A 1 40  ? 11.391  -1.554  20.600  1.00 47.10  ? 26  TRP   X CE3 1 
ATOM   162  C  CZ2 . TRP   A 1 40  ? 10.516  0.855   21.828  1.00 46.72  ? 26  TRP   X CZ2 1 
ATOM   163  C  CZ3 . TRP   A 1 40  ? 10.058  -1.211  20.642  1.00 46.93  ? 26  TRP   X CZ3 1 
ATOM   164  C  CH2 . TRP   A 1 40  ? 9.621   -0.044  21.283  1.00 49.47  ? 26  TRP   X CH2 1 
ATOM   165  N  N   . MET   A 1 41  ? 16.927  -4.001  20.973  1.00 38.77  ? 27  MET   X N   1 
ATOM   166  C  CA  . MET   A 1 41  ? 18.019  -4.652  20.212  1.00 42.54  ? 27  MET   X CA  1 
ATOM   167  C  C   . MET   A 1 41  ? 18.017  -6.153  20.493  1.00 42.13  ? 27  MET   X C   1 
ATOM   168  O  O   . MET   A 1 41  ? 18.218  -6.933  19.536  1.00 39.07  ? 27  MET   X O   1 
ATOM   169  C  CB  . MET   A 1 41  ? 19.374  -4.066  20.628  1.00 50.45  ? 27  MET   X CB  1 
ATOM   170  C  CG  . MET   A 1 41  ? 20.529  -4.449  19.733  1.00 60.03  ? 27  MET   X CG  1 
ATOM   171  S  SD  . MET   A 1 41  ? 20.858  -3.133  18.517  1.00 89.09  ? 27  MET   X SD  1 
ATOM   172  C  CE  . MET   A 1 41  ? 21.803  -1.985  19.509  1.00 72.17  ? 27  MET   X CE  1 
ATOM   173  N  N   . ILE   A 1 42  ? 17.877  -6.514  21.771  1.00 38.39  ? 28  ILE   X N   1 
ATOM   174  C  CA  . ILE   A 1 42  ? 17.969  -7.900  22.306  1.00 40.35  ? 28  ILE   X CA  1 
ATOM   175  C  C   . ILE   A 1 42  ? 16.800  -8.110  23.289  1.00 45.63  ? 28  ILE   X C   1 
ATOM   176  O  O   . ILE   A 1 42  ? 16.864  -7.625  24.459  1.00 41.60  ? 28  ILE   X O   1 
ATOM   177  C  CB  . ILE   A 1 42  ? 19.350  -8.158  22.943  1.00 40.72  ? 28  ILE   X CB  1 
ATOM   178  C  CG1 . ILE   A 1 42  ? 20.518  -7.851  21.995  1.00 44.39  ? 28  ILE   X CG1 1 
ATOM   179  C  CG2 . ILE   A 1 42  ? 19.412  -9.573  23.487  1.00 38.41  ? 28  ILE   X CG2 1 
ATOM   180  C  CD1 . ILE   A 1 42  ? 20.668  -8.853  20.853  1.00 44.43  ? 28  ILE   X CD1 1 
ATOM   181  N  N   . ALA   A 1 43  ? 15.731  -8.745  22.811  1.00 41.13  ? 29  ALA   X N   1 
ATOM   182  C  CA  . ALA   A 1 43  ? 14.492  -9.018  23.581  1.00 41.61  ? 29  ALA   X CA  1 
ATOM   183  C  C   . ALA   A 1 43  ? 14.852  -9.627  24.932  1.00 39.48  ? 29  ALA   X C   1 
ATOM   184  O  O   . ALA   A 1 43  ? 15.631  -10.612 24.931  1.00 41.17  ? 29  ALA   X O   1 
ATOM   185  C  CB  . ALA   A 1 43  ? 13.572  -9.943  22.823  1.00 40.03  ? 29  ALA   X CB  1 
ATOM   186  N  N   . MET   A 1 44  ? 14.315  -9.061  26.026  1.00 41.02  ? 30  MET   X N   1 
ATOM   187  C  CA  . MET   A 1 44  ? 14.409  -9.662  27.386  1.00 39.15  ? 30  MET   X CA  1 
ATOM   188  C  C   . MET   A 1 44  ? 15.862  -9.950  27.729  1.00 38.57  ? 30  MET   X C   1 
ATOM   189  O  O   . MET   A 1 44  ? 16.168  -11.042 28.221  1.00 47.34  ? 30  MET   X O   1 
ATOM   190  C  CB  . MET   A 1 44  ? 13.593  -10.955 27.462  1.00 41.10  ? 30  MET   X CB  1 
ATOM   191  C  CG  . MET   A 1 44  ? 12.142  -10.763 27.139  1.00 41.09  ? 30  MET   X CG  1 
ATOM   192  S  SD  . MET   A 1 44  ? 11.222  -9.507  28.124  1.00 46.03  ? 30  MET   X SD  1 
ATOM   193  C  CE  . MET   A 1 44  ? 11.771  -10.021 29.756  1.00 45.83  ? 30  MET   X CE  1 
ATOM   194  N  N   . HIS   A 1 45  ? 16.746  -8.984  27.481  1.00 43.72  ? 31  HIS   X N   1 
ATOM   195  C  CA  . HIS   A 1 45  ? 18.201  -9.176  27.663  1.00 47.12  ? 31  HIS   X CA  1 
ATOM   196  C  C   . HIS   A 1 45  ? 18.526  -9.318  29.145  1.00 47.11  ? 31  HIS   X C   1 
ATOM   197  O  O   . HIS   A 1 45  ? 19.574  -9.876  29.409  1.00 48.41  ? 31  HIS   X O   1 
ATOM   198  C  CB  . HIS   A 1 45  ? 19.019  -8.039  27.035  1.00 48.49  ? 31  HIS   X CB  1 
ATOM   199  C  CG  . HIS   A 1 45  ? 19.074  -6.790  27.839  1.00 47.24  ? 31  HIS   X CG  1 
ATOM   200  N  ND1 . HIS   A 1 45  ? 20.177  -6.462  28.607  1.00 54.14  ? 31  HIS   X ND1 1 
ATOM   201  C  CD2 . HIS   A 1 45  ? 18.211  -5.760  27.954  1.00 51.01  ? 31  HIS   X CD2 1 
ATOM   202  C  CE1 . HIS   A 1 45  ? 19.969  -5.281  29.180  1.00 47.99  ? 31  HIS   X CE1 1 
ATOM   203  N  NE2 . HIS   A 1 45  ? 18.776  -4.824  28.791  1.00 49.65  ? 31  HIS   X NE2 1 
ATOM   204  N  N   . ASN   A 1 46  ? 17.701  -8.775  30.048  1.00 45.84  ? 32  ASN   X N   1 
ATOM   205  C  CA  . ASN   A 1 46  ? 18.026  -8.724  31.504  1.00 46.36  ? 32  ASN   X CA  1 
ATOM   206  C  C   . ASN   A 1 46  ? 16.718  -8.809  32.295  1.00 42.02  ? 32  ASN   X C   1 
ATOM   207  O  O   . ASN   A 1 46  ? 16.271  -7.839  32.912  1.00 44.38  ? 32  ASN   X O   1 
ATOM   208  C  CB  . ASN   A 1 46  ? 18.885  -7.495  31.817  1.00 51.78  ? 32  ASN   X CB  1 
ATOM   209  C  CG  . ASN   A 1 46  ? 19.303  -7.423  33.273  1.00 55.55  ? 32  ASN   X CG  1 
ATOM   210  O  OD1 . ASN   A 1 46  ? 19.541  -8.448  33.900  1.00 51.17  ? 32  ASN   X OD1 1 
ATOM   211  N  ND2 . ASN   A 1 46  ? 19.286  -6.231  33.842  1.00 55.89  ? 32  ASN   X ND2 1 
ATOM   212  N  N   . PRO   A 1 47  ? 16.056  -9.984  32.298  1.00 44.16  ? 33  PRO   X N   1 
ATOM   213  C  CA  . PRO   A 1 47  ? 14.732  -10.106 32.907  1.00 44.42  ? 33  PRO   X CA  1 
ATOM   214  C  C   . PRO   A 1 47  ? 14.775  -9.884  34.428  1.00 45.44  ? 33  PRO   X C   1 
ATOM   215  O  O   . PRO   A 1 47  ? 15.696  -10.317 35.066  1.00 42.58  ? 33  PRO   X O   1 
ATOM   216  C  CB  . PRO   A 1 47  ? 14.302  -11.548 32.609  1.00 45.66  ? 33  PRO   X CB  1 
ATOM   217  C  CG  . PRO   A 1 47  ? 15.261  -12.008 31.488  1.00 51.34  ? 33  PRO   X CG  1 
ATOM   218  C  CD  . PRO   A 1 47  ? 16.553  -11.265 31.761  1.00 47.43  ? 33  PRO   X CD  1 
ATOM   219  N  N   . ALA   A 1 48  ? 13.764  -9.218  34.965  1.00 45.60  ? 34  ALA   X N   1 
ATOM   220  C  CA  . ALA   A 1 48  ? 13.511  -9.132  36.414  1.00 42.00  ? 34  ALA   X CA  1 
ATOM   221  C  C   . ALA   A 1 48  ? 13.478  -10.533 37.027  1.00 44.16  ? 34  ALA   X C   1 
ATOM   222  O  O   . ALA   A 1 48  ? 13.034  -11.527 36.364  1.00 42.89  ? 34  ALA   X O   1 
ATOM   223  C  CB  . ALA   A 1 48  ? 12.239  -8.359  36.670  1.00 46.47  ? 34  ALA   X CB  1 
ATOM   224  N  N   . THR   A 1 49  ? 13.953  -10.628 38.268  1.00 45.04  ? 35  THR   X N   1 
ATOM   225  C  CA  . THR   A 1 49  ? 13.981  -11.852 39.112  1.00 47.78  ? 35  THR   X CA  1 
ATOM   226  C  C   . THR   A 1 49  ? 13.476  -11.454 40.518  1.00 45.27  ? 35  THR   X C   1 
ATOM   227  O  O   . THR   A 1 49  ? 13.308  -10.243 40.795  1.00 45.47  ? 35  THR   X O   1 
ATOM   228  C  CB  . THR   A 1 49  ? 15.381  -12.489 39.209  1.00 48.25  ? 35  THR   X CB  1 
ATOM   229  O  OG1 . THR   A 1 49  ? 16.239  -11.504 39.785  1.00 54.21  ? 35  THR   X OG1 1 
ATOM   230  C  CG2 . THR   A 1 49  ? 15.973  -12.939 37.893  1.00 48.99  ? 35  THR   X CG2 1 
ATOM   231  N  N   . ILE   A 1 50  ? 13.149  -12.453 41.323  1.00 47.68  ? 36  ILE   X N   1 
ATOM   232  C  CA  . ILE   A 1 50  ? 12.764  -12.281 42.752  1.00 54.51  ? 36  ILE   X CA  1 
ATOM   233  C  C   . ILE   A 1 50  ? 13.843  -11.399 43.431  1.00 55.64  ? 36  ILE   X C   1 
ATOM   234  O  O   . ILE   A 1 50  ? 13.453  -10.398 44.064  1.00 54.05  ? 36  ILE   X O   1 
ATOM   235  C  CB  . ILE   A 1 50  ? 12.527  -13.679 43.368  1.00 61.07  ? 36  ILE   X CB  1 
ATOM   236  C  CG1 . ILE   A 1 50  ? 11.690  -13.607 44.649  1.00 72.25  ? 36  ILE   X CG1 1 
ATOM   237  C  CG2 . ILE   A 1 50  ? 13.842  -14.425 43.556  1.00 59.04  ? 36  ILE   X CG2 1 
ATOM   238  C  CD1 . ILE   A 1 50  ? 11.289  -14.963 45.217  1.00 72.44  ? 36  ILE   X CD1 1 
ATOM   239  N  N   . HIS   A 1 51  ? 15.135  -11.602 43.135  1.00 52.51  ? 37  HIS   X N   1 
ATOM   240  C  CA  . HIS   A 1 51  ? 16.267  -10.816 43.707  1.00 58.10  ? 37  HIS   X CA  1 
ATOM   241  C  C   . HIS   A 1 51  ? 16.429  -9.461  43.003  1.00 64.55  ? 37  HIS   X C   1 
ATOM   242  O  O   . HIS   A 1 51  ? 16.922  -8.529  43.663  1.00 57.86  ? 37  HIS   X O   1 
ATOM   243  C  CB  . HIS   A 1 51  ? 17.536  -11.684 43.793  1.00 64.23  ? 37  HIS   X CB  1 
ATOM   244  C  CG  . HIS   A 1 51  ? 17.378  -12.752 44.834  1.00 83.73  ? 37  HIS   X CG  1 
ATOM   245  N  ND1 . HIS   A 1 51  ? 17.459  -14.115 44.534  1.00 94.34  ? 37  HIS   X ND1 1 
ATOM   246  C  CD2 . HIS   A 1 51  ? 17.047  -12.676 46.150  1.00 85.35  ? 37  HIS   X CD2 1 
ATOM   247  C  CE1 . HIS   A 1 51  ? 17.233  -14.823 45.626  1.00 87.09  ? 37  HIS   X CE1 1 
ATOM   248  N  NE2 . HIS   A 1 51  ? 16.983  -13.960 46.635  1.00 91.93  ? 37  HIS   X NE2 1 
ATOM   249  N  N   . ASN   A 1 52  ? 15.994  -9.301  41.748  1.00 55.67  ? 38  ASN   X N   1 
ATOM   250  C  CA  . ASN   A 1 52  ? 16.130  -8.013  41.011  1.00 48.83  ? 38  ASN   X CA  1 
ATOM   251  C  C   . ASN   A 1 52  ? 14.785  -7.677  40.371  1.00 53.28  ? 38  ASN   X C   1 
ATOM   252  O  O   . ASN   A 1 52  ? 14.654  -7.687  39.144  1.00 48.32  ? 38  ASN   X O   1 
ATOM   253  C  CB  . ASN   A 1 52  ? 17.326  -8.041  40.040  1.00 54.47  ? 38  ASN   X CB  1 
ATOM   254  C  CG  . ASN   A 1 52  ? 17.653  -6.684  39.449  1.00 51.93  ? 38  ASN   X CG  1 
ATOM   255  O  OD1 . ASN   A 1 52  ? 17.301  -5.659  40.027  1.00 53.57  ? 38  ASN   X OD1 1 
ATOM   256  N  ND2 . ASN   A 1 52  ? 18.258  -6.656  38.269  1.00 54.62  ? 38  ASN   X ND2 1 
ATOM   257  N  N   . PRO   A 1 53  ? 13.744  -7.375  41.189  1.00 52.28  ? 39  PRO   X N   1 
ATOM   258  C  CA  . PRO   A 1 53  ? 12.367  -7.277  40.696  1.00 54.28  ? 39  PRO   X CA  1 
ATOM   259  C  C   . PRO   A 1 53  ? 12.094  -5.996  39.889  1.00 51.45  ? 39  PRO   X C   1 
ATOM   260  O  O   . PRO   A 1 53  ? 11.093  -5.934  39.143  1.00 50.78  ? 39  PRO   X O   1 
ATOM   261  C  CB  . PRO   A 1 53  ? 11.516  -7.351  41.985  1.00 53.32  ? 39  PRO   X CB  1 
ATOM   262  C  CG  . PRO   A 1 53  ? 12.433  -6.787  43.065  1.00 55.39  ? 39  PRO   X CG  1 
ATOM   263  C  CD  . PRO   A 1 53  ? 13.823  -7.241  42.660  1.00 55.02  ? 39  PRO   X CD  1 
ATOM   264  N  N   . ASN   A 1 54  ? 12.974  -5.013  40.015  1.00 44.47  ? 40  ASN   X N   1 
ATOM   265  C  CA  . ASN   A 1 54  ? 12.872  -3.730  39.271  1.00 47.22  ? 40  ASN   X CA  1 
ATOM   266  C  C   . ASN   A 1 54  ? 14.073  -3.580  38.349  1.00 46.87  ? 40  ASN   X C   1 
ATOM   267  O  O   . ASN   A 1 54  ? 14.604  -2.457  38.250  1.00 47.67  ? 40  ASN   X O   1 
ATOM   268  C  CB  . ASN   A 1 54  ? 12.766  -2.540  40.218  1.00 57.16  ? 40  ASN   X CB  1 
ATOM   269  C  CG  . ASN   A 1 54  ? 11.589  -2.701  41.150  1.00 56.59  ? 40  ASN   X CG  1 
ATOM   270  O  OD1 . ASN   A 1 54  ? 10.462  -2.868  40.693  1.00 53.72  ? 40  ASN   X OD1 1 
ATOM   271  N  ND2 . ASN   A 1 54  ? 11.849  -2.699  42.442  1.00 66.58  ? 40  ASN   X ND2 1 
ATOM   272  N  N   . ALA   A 1 55  ? 14.474  -4.672  37.702  1.00 48.37  ? 41  ALA   X N   1 
ATOM   273  C  CA  . ALA   A 1 55  ? 15.662  -4.714  36.820  1.00 44.30  ? 41  ALA   X CA  1 
ATOM   274  C  C   . ALA   A 1 55  ? 15.656  -3.496  35.909  1.00 43.52  ? 41  ALA   X C   1 
ATOM   275  O  O   . ALA   A 1 55  ? 14.571  -3.098  35.387  1.00 45.21  ? 41  ALA   X O   1 
ATOM   276  C  CB  . ALA   A 1 55  ? 15.739  -5.977  36.016  1.00 43.61  ? 41  ALA   X CB  1 
ATOM   277  N  N   . GLN   A 1 56  ? 16.849  -2.949  35.739  1.00 44.16  ? 42  GLN   X N   1 
ATOM   278  C  CA  . GLN   A 1 56  ? 17.112  -1.763  34.901  1.00 50.10  ? 42  GLN   X CA  1 
ATOM   279  C  C   . GLN   A 1 56  ? 17.575  -2.233  33.528  1.00 39.87  ? 42  GLN   X C   1 
ATOM   280  O  O   . GLN   A 1 56  ? 18.352  -3.223  33.416  1.00 44.49  ? 42  GLN   X O   1 
ATOM   281  C  CB  . GLN   A 1 56  ? 18.185  -0.875  35.535  1.00 51.83  ? 42  GLN   X CB  1 
ATOM   282  C  CG  . GLN   A 1 56  ? 17.615  -0.035  36.663  1.00 64.15  ? 42  GLN   X CG  1 
ATOM   283  C  CD  . GLN   A 1 56  ? 18.721  0.654   37.419  1.00 64.60  ? 42  GLN   X CD  1 
ATOM   284  O  OE1 . GLN   A 1 56  ? 19.722  1.079   36.835  1.00 59.52  ? 42  GLN   X OE1 1 
ATOM   285  N  NE2 . GLN   A 1 56  ? 18.560  0.697   38.731  1.00 65.01  ? 42  GLN   X NE2 1 
ATOM   286  N  N   . THR   A 1 57  ? 17.127  -1.516  32.525  1.00 43.45  ? 43  THR   X N   1 
ATOM   287  C  CA  . THR   A 1 57  ? 17.690  -1.647  31.166  1.00 45.83  ? 43  THR   X CA  1 
ATOM   288  C  C   . THR   A 1 57  ? 18.858  -0.656  31.034  1.00 47.98  ? 43  THR   X C   1 
ATOM   289  O  O   . THR   A 1 57  ? 19.218  0.015   32.036  1.00 45.02  ? 43  THR   X O   1 
ATOM   290  C  CB  . THR   A 1 57  ? 16.589  -1.476  30.113  1.00 44.65  ? 43  THR   X CB  1 
ATOM   291  O  OG1 . THR   A 1 57  ? 17.123  -1.937  28.877  1.00 44.29  ? 43  THR   X OG1 1 
ATOM   292  C  CG2 . THR   A 1 57  ? 16.100  -0.054  29.973  1.00 46.43  ? 43  THR   X CG2 1 
ATOM   293  N  N   . GLU   A 1 58  ? 19.400  -0.575  29.825  1.00 47.85  ? 44  GLU   X N   1 
ATOM   294  C  CA  . GLU   A 1 58  ? 20.503  0.327   29.410  1.00 54.99  ? 44  GLU   X CA  1 
ATOM   295  C  C   . GLU   A 1 58  ? 20.057  1.030   28.144  1.00 49.01  ? 44  GLU   X C   1 
ATOM   296  O  O   . GLU   A 1 58  ? 19.198  0.487   27.440  1.00 43.25  ? 44  GLU   X O   1 
ATOM   297  C  CB  . GLU   A 1 58  ? 21.774  -0.438  29.027  1.00 62.28  ? 44  GLU   X CB  1 
ATOM   298  C  CG  . GLU   A 1 58  ? 22.418  -1.170  30.173  1.00 71.38  ? 44  GLU   X CG  1 
ATOM   299  C  CD  . GLU   A 1 58  ? 22.257  -2.672  30.076  1.00 89.50  ? 44  GLU   X CD  1 
ATOM   300  O  OE1 . GLU   A 1 58  ? 21.480  -3.229  30.903  1.00 82.00  ? 44  GLU   X OE1 1 
ATOM   301  O  OE2 . GLU   A 1 58  ? 22.907  -3.270  29.166  1.00 94.79  ? 44  GLU   X OE2 1 
ATOM   302  N  N   . PHE   A 1 59  ? 20.691  2.149   27.848  1.00 42.39  ? 45  PHE   X N   1 
ATOM   303  C  CA  . PHE   A 1 59  ? 20.427  2.997   26.673  1.00 43.53  ? 45  PHE   X CA  1 
ATOM   304  C  C   . PHE   A 1 59  ? 21.679  2.914   25.808  1.00 53.78  ? 45  PHE   X C   1 
ATOM   305  O  O   . PHE   A 1 59  ? 22.642  3.606   26.156  1.00 51.00  ? 45  PHE   X O   1 
ATOM   306  C  CB  . PHE   A 1 59  ? 20.078  4.394   27.167  1.00 42.33  ? 45  PHE   X CB  1 
ATOM   307  C  CG  . PHE   A 1 59  ? 19.256  5.244   26.240  1.00 43.22  ? 45  PHE   X CG  1 
ATOM   308  C  CD1 . PHE   A 1 59  ? 18.007  4.820   25.821  1.00 44.10  ? 45  PHE   X CD1 1 
ATOM   309  C  CD2 . PHE   A 1 59  ? 19.704  6.493   25.837  1.00 45.21  ? 45  PHE   X CD2 1 
ATOM   310  C  CE1 . PHE   A 1 59  ? 17.223  5.614   25.003  1.00 43.16  ? 45  PHE   X CE1 1 
ATOM   311  C  CE2 . PHE   A 1 59  ? 18.919  7.293   25.023  1.00 48.17  ? 45  PHE   X CE2 1 
ATOM   312  C  CZ  . PHE   A 1 59  ? 17.683  6.847   24.601  1.00 51.85  ? 45  PHE   X CZ  1 
ATOM   313  N  N   . VAL   A 1 60  ? 21.680  2.044   24.789  1.00 45.84  ? 46  VAL   X N   1 
ATOM   314  C  CA  . VAL   A 1 60  ? 22.916  1.612   24.076  1.00 43.91  ? 46  VAL   X CA  1 
ATOM   315  C  C   . VAL   A 1 60  ? 23.038  2.401   22.781  1.00 42.32  ? 46  VAL   X C   1 
ATOM   316  O  O   . VAL   A 1 60  ? 22.022  2.772   22.190  1.00 39.61  ? 46  VAL   X O   1 
ATOM   317  C  CB  . VAL   A 1 60  ? 22.972  0.097   23.804  1.00 50.77  ? 46  VAL   X CB  1 
ATOM   318  C  CG1 . VAL   A 1 60  ? 23.091  -0.680  25.095  1.00 53.92  ? 46  VAL   X CG1 1 
ATOM   319  C  CG2 . VAL   A 1 60  ? 21.790  -0.384  22.977  1.00 48.43  ? 46  VAL   X CG2 1 
ATOM   320  N  N   . GLU   A 1 61  ? 24.280  2.690   22.410  1.00 43.77  ? 47  GLU   X N   1 
ATOM   321  C  CA  . GLU   A 1 61  ? 24.649  3.519   21.250  1.00 41.75  ? 47  GLU   X CA  1 
ATOM   322  C  C   . GLU   A 1 61  ? 25.068  2.618   20.084  1.00 38.71  ? 47  GLU   X C   1 
ATOM   323  O  O   . GLU   A 1 61  ? 25.778  1.643   20.289  1.00 42.22  ? 47  GLU   X O   1 
ATOM   324  C  CB  . GLU   A 1 61  ? 25.814  4.445   21.603  1.00 46.49  ? 47  GLU   X CB  1 
ATOM   325  C  CG  . GLU   A 1 61  ? 25.963  5.534   20.560  1.00 50.11  ? 47  GLU   X CG  1 
ATOM   326  C  CD  . GLU   A 1 61  ? 27.087  6.530   20.776  1.00 52.15  ? 47  GLU   X CD  1 
ATOM   327  O  OE1 . GLU   A 1 61  ? 28.232  6.104   20.774  1.00 56.51  ? 47  GLU   X OE1 1 
ATOM   328  O  OE2 . GLU   A 1 61  ? 26.793  7.724   20.812  1.00 55.30  ? 47  GLU   X OE2 1 
ATOM   329  N  N   . PHE   A 1 62  ? 24.719  2.979   18.870  1.00 40.48  ? 48  PHE   X N   1 
ATOM   330  C  CA  . PHE   A 1 62  ? 25.055  2.136   17.704  1.00 39.89  ? 48  PHE   X CA  1 
ATOM   331  C  C   . PHE   A 1 62  ? 25.156  3.014   16.465  1.00 38.08  ? 48  PHE   X C   1 
ATOM   332  O  O   . PHE   A 1 62  ? 24.565  4.097   16.383  1.00 40.14  ? 48  PHE   X O   1 
ATOM   333  C  CB  . PHE   A 1 62  ? 24.034  0.987   17.619  1.00 40.68  ? 48  PHE   X CB  1 
ATOM   334  C  CG  . PHE   A 1 62  ? 22.607  1.435   17.483  1.00 38.56  ? 48  PHE   X CG  1 
ATOM   335  C  CD1 . PHE   A 1 62  ? 22.064  1.723   16.239  1.00 38.50  ? 48  PHE   X CD1 1 
ATOM   336  C  CD2 . PHE   A 1 62  ? 21.800  1.556   18.604  1.00 40.73  ? 48  PHE   X CD2 1 
ATOM   337  C  CE1 . PHE   A 1 62  ? 20.743  2.147   16.120  1.00 42.34  ? 48  PHE   X CE1 1 
ATOM   338  C  CE2 . PHE   A 1 62  ? 20.491  1.992   18.487  1.00 43.12  ? 48  PHE   X CE2 1 
ATOM   339  C  CZ  . PHE   A 1 62  ? 19.958  2.286   17.246  1.00 40.74  ? 48  PHE   X CZ  1 
ATOM   340  N  N   . PRO   A 1 63  ? 25.914  2.548   15.457  1.00 37.43  ? 49  PRO   X N   1 
ATOM   341  C  CA  . PRO   A 1 63  ? 26.073  3.275   14.219  1.00 36.52  ? 49  PRO   X CA  1 
ATOM   342  C  C   . PRO   A 1 63  ? 24.881  3.134   13.273  1.00 38.15  ? 49  PRO   X C   1 
ATOM   343  O  O   . PRO   A 1 63  ? 24.259  2.063   13.162  1.00 40.06  ? 49  PRO   X O   1 
ATOM   344  C  CB  . PRO   A 1 63  ? 27.308  2.607   13.581  1.00 39.24  ? 49  PRO   X CB  1 
ATOM   345  C  CG  . PRO   A 1 63  ? 27.251  1.203   14.081  1.00 38.25  ? 49  PRO   X CG  1 
ATOM   346  C  CD  . PRO   A 1 63  ? 26.683  1.295   15.477  1.00 39.73  ? 49  PRO   X CD  1 
ATOM   347  N  N   . ILE   A 1 64  ? 24.647  4.217   12.563  1.00 37.26  ? 50  ILE   X N   1 
ATOM   348  C  CA  . ILE   A 1 64  ? 23.819  4.264   11.325  1.00 38.67  ? 50  ILE   X CA  1 
ATOM   349  C  C   . ILE   A 1 64  ? 24.800  4.422   10.179  1.00 40.62  ? 50  ILE   X C   1 
ATOM   350  O  O   . ILE   A 1 64  ? 25.619  5.386   10.234  1.00 39.60  ? 50  ILE   X O   1 
ATOM   351  C  CB  . ILE   A 1 64  ? 22.835  5.443   11.373  1.00 38.80  ? 50  ILE   X CB  1 
ATOM   352  C  CG1 . ILE   A 1 64  ? 22.104  5.543   12.719  1.00 41.61  ? 50  ILE   X CG1 1 
ATOM   353  C  CG2 . ILE   A 1 64  ? 21.889  5.418   10.194  1.00 40.12  ? 50  ILE   X CG2 1 
ATOM   354  C  CD1 . ILE   A 1 64  ? 21.276  4.372   13.058  1.00 45.91  ? 50  ILE   X CD1 1 
ATOM   355  N  N   . TYR   A 1 65  ? 24.718  3.566   9.167   1.00 35.24  ? 51  TYR   X N   1 
ATOM   356  C  CA  . TYR   A 1 65  ? 25.624  3.659   8.002   1.00 35.02  ? 51  TYR   X CA  1 
ATOM   357  C  C   . TYR   A 1 65  ? 24.923  3.220   6.728   1.00 38.84  ? 51  TYR   X C   1 
ATOM   358  O  O   . TYR   A 1 65  ? 23.838  2.643   6.810   1.00 35.89  ? 51  TYR   X O   1 
ATOM   359  C  CB  . TYR   A 1 65  ? 26.887  2.833   8.247   1.00 34.15  ? 51  TYR   X CB  1 
ATOM   360  C  CG  . TYR   A 1 65  ? 26.777  1.335   8.151   1.00 33.48  ? 51  TYR   X CG  1 
ATOM   361  C  CD1 . TYR   A 1 65  ? 26.320  0.572   9.219   1.00 39.58  ? 51  TYR   X CD1 1 
ATOM   362  C  CD2 . TYR   A 1 65  ? 27.211  0.665   7.024   1.00 35.47  ? 51  TYR   X CD2 1 
ATOM   363  C  CE1 . TYR   A 1 65  ? 26.261  -0.819  9.139   1.00 36.15  ? 51  TYR   X CE1 1 
ATOM   364  C  CE2 . TYR   A 1 65  ? 27.148  -0.717  6.919   1.00 39.22  ? 51  TYR   X CE2 1 
ATOM   365  C  CZ  . TYR   A 1 65  ? 26.699  -1.471  7.989   1.00 37.45  ? 51  TYR   X CZ  1 
ATOM   366  O  OH  . TYR   A 1 65  ? 26.701  -2.841  7.849   1.00 36.94  ? 51  TYR   X OH  1 
ATOM   367  N  N   . THR   A 1 66  ? 25.552  3.571   5.622   1.00 33.86  ? 52  THR   X N   1 
ATOM   368  C  CA  . THR   A 1 66  ? 25.134  3.342   4.240   1.00 35.61  ? 52  THR   X CA  1 
ATOM   369  C  C   . THR   A 1 66  ? 26.336  2.815   3.451   1.00 38.89  ? 52  THR   X C   1 
ATOM   370  O  O   . THR   A 1 66  ? 27.502  2.981   3.897   1.00 35.28  ? 52  THR   X O   1 
ATOM   371  C  CB  . THR   A 1 66  ? 24.563  4.626   3.629   1.00 40.90  ? 52  THR   X CB  1 
ATOM   372  O  OG1 . THR   A 1 66  ? 25.511  5.677   3.812   1.00 39.81  ? 52  THR   X OG1 1 
ATOM   373  C  CG2 . THR   A 1 66  ? 23.241  5.026   4.253   1.00 38.79  ? 52  THR   X CG2 1 
ATOM   374  N  N   . VAL   A 1 67  ? 26.059  2.126   2.351   1.00 36.62  ? 53  VAL   X N   1 
ATOM   375  C  CA  . VAL   A 1 67  ? 27.101  1.502   1.501   1.00 35.46  ? 53  VAL   X CA  1 
ATOM   376  C  C   . VAL   A 1 67  ? 26.885  2.018   0.085   1.00 36.77  ? 53  VAL   X C   1 
ATOM   377  O  O   . VAL   A 1 67  ? 25.752  1.918   -0.409  1.00 37.60  ? 53  VAL   X O   1 
ATOM   378  C  CB  . VAL   A 1 67  ? 27.091  -0.037  1.565   1.00 33.91  ? 53  VAL   X CB  1 
ATOM   379  C  CG1 . VAL   A 1 67  ? 28.022  -0.640  0.531   1.00 34.88  ? 53  VAL   X CG1 1 
ATOM   380  C  CG2 . VAL   A 1 67  ? 27.457  -0.551  2.951   1.00 36.50  ? 53  VAL   X CG2 1 
ATOM   381  N  N   . LEU   A 1 68  ? 27.934  2.589   -0.511  1.00 35.46  ? 54  LEU   X N   1 
ATOM   382  C  CA  . LEU   A 1 68  ? 27.987  2.959   -1.948  1.00 35.39  ? 54  LEU   X CA  1 
ATOM   383  C  C   . LEU   A 1 68  ? 28.808  1.918   -2.687  1.00 34.85  ? 54  LEU   X C   1 
ATOM   384  O  O   . LEU   A 1 68  ? 29.961  1.695   -2.295  1.00 36.52  ? 54  LEU   X O   1 
ATOM   385  C  CB  . LEU   A 1 68  ? 28.619  4.342   -2.118  1.00 36.88  ? 54  LEU   X CB  1 
ATOM   386  C  CG  . LEU   A 1 68  ? 28.795  4.809   -3.564  1.00 36.74  ? 54  LEU   X CG  1 
ATOM   387  C  CD1 . LEU   A 1 68  ? 27.430  5.065   -4.180  1.00 39.24  ? 54  LEU   X CD1 1 
ATOM   388  C  CD2 . LEU   A 1 68  ? 29.623  6.107   -3.613  1.00 39.40  ? 54  LEU   X CD2 1 
ATOM   389  N  N   . ILE   A 1 69  ? 28.250  1.338   -3.750  1.00 35.10  ? 55  ILE   X N   1 
ATOM   390  C  CA  . ILE   A 1 69  ? 29.008  0.492   -4.694  1.00 39.51  ? 55  ILE   X CA  1 
ATOM   391  C  C   . ILE   A 1 69  ? 29.226  1.344   -5.946  1.00 42.06  ? 55  ILE   X C   1 
ATOM   392  O  O   . ILE   A 1 69  ? 28.261  1.591   -6.691  1.00 37.13  ? 55  ILE   X O   1 
ATOM   393  C  CB  . ILE   A 1 69  ? 28.324  -0.863  -4.962  1.00 42.48  ? 55  ILE   X CB  1 
ATOM   394  C  CG1 . ILE   A 1 69  ? 28.088  -1.677  -3.682  1.00 45.19  ? 55  ILE   X CG1 1 
ATOM   395  C  CG2 . ILE   A 1 69  ? 29.144  -1.676  -5.952  1.00 42.42  ? 55  ILE   X CG2 1 
ATOM   396  C  CD1 . ILE   A 1 69  ? 26.859  -1.312  -2.924  1.00 53.55  ? 55  ILE   X CD1 1 
ATOM   397  N  N   . ASP   A 1 70  ? 30.443  1.859   -6.131  1.00 40.15  ? 56  ASP   X N   1 
ATOM   398  C  CA  . ASP   A 1 70  ? 30.835  2.573   -7.377  1.00 41.07  ? 56  ASP   X CA  1 
ATOM   399  C  C   . ASP   A 1 70  ? 31.160  1.513   -8.423  1.00 38.00  ? 56  ASP   X C   1 
ATOM   400  O  O   . ASP   A 1 70  ? 32.255  1.007   -8.460  1.00 38.32  ? 56  ASP   X O   1 
ATOM   401  C  CB  . ASP   A 1 70  ? 31.975  3.569   -7.132  1.00 44.44  ? 56  ASP   X CB  1 
ATOM   402  C  CG  . ASP   A 1 70  ? 32.280  4.413   -8.350  1.00 46.92  ? 56  ASP   X CG  1 
ATOM   403  O  OD1 . ASP   A 1 70  ? 31.463  4.402   -9.282  1.00 49.00  ? 56  ASP   X OD1 1 
ATOM   404  O  OD2 . ASP   A 1 70  ? 33.338  5.049   -8.357  1.00 51.05  ? 56  ASP   X OD2 1 
ATOM   405  N  N   . HIS   A 1 71  ? 30.166  1.144   -9.212  1.00 40.10  ? 57  HIS   X N   1 
ATOM   406  C  CA  . HIS   A 1 71  ? 30.228  0.022   -10.177 1.00 40.57  ? 57  HIS   X CA  1 
ATOM   407  C  C   . HIS   A 1 71  ? 30.312  0.627   -11.574 1.00 36.35  ? 57  HIS   X C   1 
ATOM   408  O  O   . HIS   A 1 71  ? 29.618  1.601   -11.868 1.00 44.89  ? 57  HIS   X O   1 
ATOM   409  C  CB  . HIS   A 1 71  ? 28.977  -0.868  -9.998  1.00 39.53  ? 57  HIS   X CB  1 
ATOM   410  C  CG  . HIS   A 1 71  ? 29.111  -2.239  -10.552 1.00 42.85  ? 57  HIS   X CG  1 
ATOM   411  N  ND1 . HIS   A 1 71  ? 29.104  -2.481  -11.905 1.00 39.48  ? 57  HIS   X ND1 1 
ATOM   412  C  CD2 . HIS   A 1 71  ? 29.295  -3.431  -9.934  1.00 42.24  ? 57  HIS   X CD2 1 
ATOM   413  C  CE1 . HIS   A 1 71  ? 29.256  -3.775  -12.102 1.00 41.75  ? 57  HIS   X CE1 1 
ATOM   414  N  NE2 . HIS   A 1 71  ? 29.414  -4.381  -10.899 1.00 39.31  ? 57  HIS   X NE2 1 
ATOM   415  N  N   . PRO   A 1 72  ? 31.091  0.059   -12.504 1.00 43.46  ? 58  PRO   X N   1 
ATOM   416  C  CA  . PRO   A 1 72  ? 31.092  0.577   -13.877 1.00 45.92  ? 58  PRO   X CA  1 
ATOM   417  C  C   . PRO   A 1 72  ? 29.712  0.573   -14.550 1.00 51.94  ? 58  PRO   X C   1 
ATOM   418  O  O   . PRO   A 1 72  ? 29.476  1.406   -15.441 1.00 44.34  ? 58  PRO   X O   1 
ATOM   419  C  CB  . PRO   A 1 72  ? 32.060  -0.356  -14.621 1.00 48.36  ? 58  PRO   X CB  1 
ATOM   420  C  CG  . PRO   A 1 72  ? 32.314  -1.527  -13.706 1.00 49.28  ? 58  PRO   X CG  1 
ATOM   421  C  CD  . PRO   A 1 72  ? 32.021  -1.062  -12.296 1.00 46.14  ? 58  PRO   X CD  1 
ATOM   422  N  N   . GLU   A 1 73  ? 28.803  -0.327  -14.129 1.00 42.37  ? 59  GLU   X N   1 
ATOM   423  C  CA  . GLU   A 1 73  ? 27.455  -0.379  -14.747 1.00 42.86  ? 59  GLU   X CA  1 
ATOM   424  C  C   . GLU   A 1 73  ? 26.552  0.667   -14.109 1.00 42.16  ? 59  GLU   X C   1 
ATOM   425  O  O   . GLU   A 1 73  ? 25.451  0.800   -14.591 1.00 46.96  ? 59  GLU   X O   1 
ATOM   426  C  CB  . GLU   A 1 73  ? 26.831  -1.768  -14.633 1.00 45.92  ? 59  GLU   X CB  1 
ATOM   427  C  CG  . GLU   A 1 73  ? 27.578  -2.851  -15.383 1.00 47.01  ? 59  GLU   X CG  1 
ATOM   428  C  CD  . GLU   A 1 73  ? 26.982  -4.222  -15.084 1.00 51.69  ? 59  GLU   X CD  1 
ATOM   429  O  OE1 . GLU   A 1 73  ? 25.758  -4.333  -15.143 1.00 53.24  ? 59  GLU   X OE1 1 
ATOM   430  O  OE2 . GLU   A 1 73  ? 27.738  -5.184  -14.793 1.00 46.71  ? 59  GLU   X OE2 1 
ATOM   431  N  N   . GLY   A 1 74  ? 27.003  1.388   -13.082 1.00 38.24  ? 60  GLY   X N   1 
ATOM   432  C  CA  . GLY   A 1 74  ? 26.240  2.483   -12.446 1.00 40.85  ? 60  GLY   X CA  1 
ATOM   433  C  C   . GLY   A 1 74  ? 26.332  2.382   -10.935 1.00 41.15  ? 60  GLY   X C   1 
ATOM   434  O  O   . GLY   A 1 74  ? 26.585  1.284   -10.432 1.00 48.17  ? 60  GLY   X O   1 
ATOM   435  N  N   . LYS   A 1 75  ? 26.221  3.501   -10.244 1.00 38.80  ? 61  LYS   X N   1 
ATOM   436  C  CA  . LYS   A 1 75  ? 26.395  3.596   -8.787  1.00 38.23  ? 61  LYS   X CA  1 
ATOM   437  C  C   . LYS   A 1 75  ? 25.150  3.037   -8.093  1.00 36.38  ? 61  LYS   X C   1 
ATOM   438  O  O   . LYS   A 1 75  ? 24.008  3.414   -8.466  1.00 38.19  ? 61  LYS   X O   1 
ATOM   439  C  CB  . LYS   A 1 75  ? 26.700  5.051   -8.450  1.00 43.37  ? 61  LYS   X CB  1 
ATOM   440  C  CG  . LYS   A 1 75  ? 28.070  5.516   -8.965  1.00 45.86  ? 61  LYS   X CG  1 
ATOM   441  C  CD  . LYS   A 1 75  ? 28.358  6.980   -8.688  1.00 51.18  ? 61  LYS   X CD  1 
ATOM   442  C  CE  . LYS   A 1 75  ? 29.777  7.453   -9.005  1.00 49.89  ? 61  LYS   X CE  1 
ATOM   443  N  NZ  . LYS   A 1 75  ? 30.319  6.881   -10.261 1.00 48.50  ? 61  LYS   X NZ  1 
ATOM   444  N  N   . ILE   A 1 76  ? 25.377  2.166   -7.127  1.00 37.71  ? 62  ILE   X N   1 
ATOM   445  C  CA  . ILE   A 1 76  ? 24.323  1.508   -6.302  1.00 36.84  ? 62  ILE   X CA  1 
ATOM   446  C  C   . ILE   A 1 76  ? 24.514  1.963   -4.855  1.00 38.15  ? 62  ILE   X C   1 
ATOM   447  O  O   . ILE   A 1 76  ? 25.581  1.752   -4.292  1.00 38.20  ? 62  ILE   X O   1 
ATOM   448  C  CB  . ILE   A 1 76  ? 24.382  -0.033  -6.455  1.00 40.23  ? 62  ILE   X CB  1 
ATOM   449  C  CG1 . ILE   A 1 76  ? 24.184  -0.459  -7.912  1.00 38.58  ? 62  ILE   X CG1 1 
ATOM   450  C  CG2 . ILE   A 1 76  ? 23.360  -0.715  -5.549  1.00 39.65  ? 62  ILE   X CG2 1 
ATOM   451  C  CD1 . ILE   A 1 76  ? 24.799  -1.761  -8.182  1.00 38.93  ? 62  ILE   X CD1 1 
ATOM   452  N  N   . LEU   A 1 77  ? 23.458  2.495   -4.250  1.00 34.90  ? 63  LEU   X N   1 
ATOM   453  C  CA  . LEU   A 1 77  ? 23.439  2.868   -2.828  1.00 34.92  ? 63  LEU   X CA  1 
ATOM   454  C  C   . LEU   A 1 77  ? 22.574  1.859   -2.049  1.00 36.72  ? 63  LEU   X C   1 
ATOM   455  O  O   . LEU   A 1 77  ? 21.421  1.668   -2.434  1.00 35.78  ? 63  LEU   X O   1 
ATOM   456  C  CB  . LEU   A 1 77  ? 22.855  4.274   -2.755  1.00 34.57  ? 63  LEU   X CB  1 
ATOM   457  C  CG  . LEU   A 1 77  ? 22.835  4.925   -1.376  1.00 37.39  ? 63  LEU   X CG  1 
ATOM   458  C  CD1 . LEU   A 1 77  ? 24.222  4.982   -0.791  1.00 46.12  ? 63  LEU   X CD1 1 
ATOM   459  C  CD2 . LEU   A 1 77  ? 22.256  6.318   -1.480  1.00 40.31  ? 63  LEU   X CD2 1 
ATOM   460  N  N   . PHE   A 1 78  ? 23.073  1.331   -0.945  1.00 34.79  ? 64  PHE   X N   1 
ATOM   461  C  CA  . PHE   A 1 78  ? 22.315  0.459   -0.008  1.00 33.94  ? 64  PHE   X CA  1 
ATOM   462  C  C   . PHE   A 1 78  ? 21.990  1.278   1.241   1.00 36.48  ? 64  PHE   X C   1 
ATOM   463  O  O   . PHE   A 1 78  ? 22.921  1.691   1.967   1.00 34.60  ? 64  PHE   X O   1 
ATOM   464  C  CB  . PHE   A 1 78  ? 23.106  -0.828  0.270   1.00 34.11  ? 64  PHE   X CB  1 
ATOM   465  C  CG  . PHE   A 1 78  ? 22.388  -1.804  1.166   1.00 31.58  ? 64  PHE   X CG  1 
ATOM   466  C  CD1 . PHE   A 1 78  ? 21.445  -2.675  0.641   1.00 34.04  ? 64  PHE   X CD1 1 
ATOM   467  C  CD2 . PHE   A 1 78  ? 22.618  -1.822  2.532   1.00 32.60  ? 64  PHE   X CD2 1 
ATOM   468  C  CE1 . PHE   A 1 78  ? 20.768  -3.578  1.456   1.00 35.58  ? 64  PHE   X CE1 1 
ATOM   469  C  CE2 . PHE   A 1 78  ? 21.934  -2.707  3.357   1.00 33.81  ? 64  PHE   X CE2 1 
ATOM   470  C  CZ  . PHE   A 1 78  ? 21.010  -3.596  2.809   1.00 35.37  ? 64  PHE   X CZ  1 
ATOM   471  N  N   . ASP   A 1 79  ? 20.710  1.595   1.438   1.00 31.40  ? 65  ASP   X N   1 
ATOM   472  C  CA  . ASP   A 1 79  ? 20.175  2.365   2.607   1.00 35.54  ? 65  ASP   X CA  1 
ATOM   473  C  C   . ASP   A 1 79  ? 20.539  3.853   2.436   1.00 35.77  ? 65  ASP   X C   1 
ATOM   474  O  O   . ASP   A 1 79  ? 21.346  4.145   1.549   1.00 32.17  ? 65  ASP   X O   1 
ATOM   475  C  CB  . ASP   A 1 79  ? 20.592  1.813   3.981   1.00 35.85  ? 65  ASP   X CB  1 
ATOM   476  C  CG  . ASP   A 1 79  ? 19.773  0.607   4.474   1.00 44.07  ? 65  ASP   X CG  1 
ATOM   477  O  OD1 . ASP   A 1 79  ? 18.701  0.360   3.877   1.00 38.95  ? 65  ASP   X OD1 1 
ATOM   478  O  OD2 . ASP   A 1 79  ? 20.204  -0.106  5.442   1.00 41.27  ? 65  ASP   X OD2 1 
ATOM   479  N  N   . THR   A 1 80  ? 19.933  4.740   3.225   1.00 35.54  ? 66  THR   X N   1 
ATOM   480  C  CA  . THR   A 1 80  ? 20.064  6.204   3.013   1.00 36.40  ? 66  THR   X CA  1 
ATOM   481  C  C   . THR   A 1 80  ? 20.137  6.948   4.346   1.00 34.46  ? 66  THR   X C   1 
ATOM   482  O  O   . THR   A 1 80  ? 20.022  8.193   4.299   1.00 41.09  ? 66  THR   X O   1 
ATOM   483  C  CB  . THR   A 1 80  ? 18.946  6.766   2.124   1.00 35.81  ? 66  THR   X CB  1 
ATOM   484  O  OG1 . THR   A 1 80  ? 17.743  6.781   2.888   1.00 34.89  ? 66  THR   X OG1 1 
ATOM   485  C  CG2 . THR   A 1 80  ? 18.741  6.003   0.839   1.00 39.22  ? 66  THR   X CG2 1 
ATOM   486  N  N   . SER   A 1 81  ? 20.222  6.234   5.471   1.00 33.04  ? 67  SER   X N   1 
ATOM   487  C  CA  . SER   A 1 81  ? 20.344  6.795   6.833   1.00 35.66  ? 67  SER   X CA  1 
ATOM   488  C  C   . SER   A 1 81  ? 19.135  7.688   7.152   1.00 38.02  ? 67  SER   X C   1 
ATOM   489  O  O   . SER   A 1 81  ? 18.006  7.333   6.726   1.00 40.28  ? 67  SER   X O   1 
ATOM   490  C  CB  . SER   A 1 81  ? 21.708  7.512   7.020   1.00 38.60  ? 67  SER   X CB  1 
ATOM   491  O  OG  . SER   A 1 81  ? 21.738  8.737   6.311   1.00 38.72  ? 67  SER   X OG  1 
ATOM   492  N  N   . CYS   A 1 82  ? 19.312  8.691   8.016   1.00 34.59  ? 68  CYS   X N   1 
ATOM   493  C  CA  . CYS   A 1 82  ? 18.210  9.522   8.587   1.00 37.39  ? 68  CYS   X CA  1 
ATOM   494  C  C   . CYS   A 1 82  ? 18.158  10.860  7.838   1.00 39.79  ? 68  CYS   X C   1 
ATOM   495  O  O   . CYS   A 1 82  ? 19.205  11.331  7.305   1.00 38.35  ? 68  CYS   X O   1 
ATOM   496  C  CB  . CYS   A 1 82  ? 18.384  9.783   10.083  1.00 35.98  ? 68  CYS   X CB  1 
ATOM   497  S  SG  . CYS   A 1 82  ? 18.750  8.326   11.094  1.00 39.01  ? 68  CYS   X SG  1 
ATOM   498  N  N   . ASN   A 1 83  ? 16.994  11.481  7.770   1.00 35.56  ? 69  ASN   X N   1 
ATOM   499  C  CA  . ASN   A 1 83  ? 16.919  12.800  7.106   1.00 39.29  ? 69  ASN   X CA  1 
ATOM   500  C  C   . ASN   A 1 83  ? 17.670  13.815  7.978   1.00 37.47  ? 69  ASN   X C   1 
ATOM   501  O  O   . ASN   A 1 83  ? 17.559  13.810  9.200   1.00 35.33  ? 69  ASN   X O   1 
ATOM   502  C  CB  . ASN   A 1 83  ? 15.474  13.230  6.838   1.00 39.13  ? 69  ASN   X CB  1 
ATOM   503  C  CG  . ASN   A 1 83  ? 15.436  14.332  5.808   1.00 39.83  ? 69  ASN   X CG  1 
ATOM   504  O  OD1 . ASN   A 1 83  ? 15.469  14.098  4.592   1.00 40.56  ? 69  ASN   X OD1 1 
ATOM   505  N  ND2 . ASN   A 1 83  ? 15.394  15.545  6.303   1.00 37.89  ? 69  ASN   X ND2 1 
ATOM   506  N  N   . PRO   A 1 84  ? 18.465  14.736  7.398   1.00 40.20  ? 70  PRO   X N   1 
ATOM   507  C  CA  . PRO   A 1 84  ? 19.061  15.829  8.193   1.00 45.75  ? 70  PRO   X CA  1 
ATOM   508  C  C   . PRO   A 1 84  ? 18.068  16.668  9.023   1.00 46.97  ? 70  PRO   X C   1 
ATOM   509  O  O   . PRO   A 1 84  ? 18.447  17.284  9.982   1.00 44.90  ? 70  PRO   X O   1 
ATOM   510  C  CB  . PRO   A 1 84  ? 19.715  16.745  7.142   1.00 40.92  ? 70  PRO   X CB  1 
ATOM   511  C  CG  . PRO   A 1 84  ? 19.952  15.832  5.951   1.00 46.59  ? 70  PRO   X CG  1 
ATOM   512  C  CD  . PRO   A 1 84  ? 18.800  14.826  5.968   1.00 40.88  ? 70  PRO   X CD  1 
ATOM   513  N  N   . ASN   A 1 85  ? 16.791  16.686  8.658   1.00 43.58  ? 71  ASN   X N   1 
ATOM   514  C  CA  . ASN   A 1 85  ? 15.763  17.463  9.402   1.00 43.43  ? 71  ASN   X CA  1 
ATOM   515  C  C   . ASN   A 1 85  ? 14.998  16.561  10.372  1.00 42.78  ? 71  ASN   X C   1 
ATOM   516  O  O   . ASN   A 1 85  ? 13.853  16.918  10.704  1.00 42.93  ? 71  ASN   X O   1 
ATOM   517  C  CB  . ASN   A 1 85  ? 14.736  18.095  8.468   1.00 52.89  ? 71  ASN   X CB  1 
ATOM   518  C  CG  . ASN   A 1 85  ? 15.392  18.844  7.335   1.00 61.30  ? 71  ASN   X CG  1 
ATOM   519  O  OD1 . ASN   A 1 85  ? 15.358  18.420  6.163   1.00 69.77  ? 71  ASN   X OD1 1 
ATOM   520  N  ND2 . ASN   A 1 85  ? 16.039  19.935  7.708   1.00 59.99  ? 71  ASN   X ND2 1 
ATOM   521  N  N   . SER   A 1 86  ? 15.582  15.448  10.825  1.00 40.63  ? 72  SER   X N   1 
ATOM   522  C  CA  . SER   A 1 86  ? 14.849  14.480  11.688  1.00 40.38  ? 72  SER   X CA  1 
ATOM   523  C  C   . SER   A 1 86  ? 14.632  15.093  13.076  1.00 40.64  ? 72  SER   X C   1 
ATOM   524  O  O   . SER   A 1 86  ? 13.483  15.068  13.580  1.00 41.53  ? 72  SER   X O   1 
ATOM   525  C  CB  . SER   A 1 86  ? 15.560  13.176  11.788  1.00 37.25  ? 72  SER   X CB  1 
ATOM   526  O  OG  . SER   A 1 86  ? 15.670  12.567  10.507  1.00 40.21  ? 72  SER   X OG  1 
ATOM   527  N  N   . MET   A 1 87  ? 15.703  15.611  13.666  1.00 39.25  ? 73  MET   X N   1 
ATOM   528  C  CA  . MET   A 1 87  ? 15.754  15.898  15.114  1.00 41.55  ? 73  MET   X CA  1 
ATOM   529  C  C   . MET   A 1 87  ? 15.461  17.387  15.346  1.00 44.61  ? 73  MET   X C   1 
ATOM   530  O  O   . MET   A 1 87  ? 15.592  18.182  14.412  1.00 43.43  ? 73  MET   X O   1 
ATOM   531  C  CB  . MET   A 1 87  ? 17.122  15.528  15.710  1.00 47.29  ? 73  MET   X CB  1 
ATOM   532  C  CG  . MET   A 1 87  ? 17.440  14.024  15.683  1.00 43.07  ? 73  MET   X CG  1 
ATOM   533  S  SD  . MET   A 1 87  ? 16.523  13.066  16.880  1.00 43.36  ? 73  MET   X SD  1 
ATOM   534  C  CE  . MET   A 1 87  ? 17.041  13.743  18.465  1.00 52.03  ? 73  MET   X CE  1 
ATOM   535  N  N   . GLY   A 1 88  ? 15.069  17.731  16.567  1.00 48.16  ? 74  GLY   X N   1 
ATOM   536  C  CA  . GLY   A 1 88  ? 14.958  19.124  17.008  1.00 54.14  ? 74  GLY   X CA  1 
ATOM   537  C  C   . GLY   A 1 88  ? 13.508  19.565  17.101  1.00 56.98  ? 74  GLY   X C   1 
ATOM   538  O  O   . GLY   A 1 88  ? 12.596  18.845  16.675  1.00 54.05  ? 74  GLY   X O   1 
ATOM   539  N  N   . PRO   A 1 89  ? 13.268  20.771  17.658  1.00 54.73  ? 75  PRO   X N   1 
ATOM   540  C  CA  . PRO   A 1 89  ? 11.903  21.268  17.874  1.00 57.90  ? 75  PRO   X CA  1 
ATOM   541  C  C   . PRO   A 1 89  ? 11.076  21.392  16.581  1.00 50.48  ? 75  PRO   X C   1 
ATOM   542  O  O   . PRO   A 1 89  ? 9.899   21.153  16.659  1.00 51.74  ? 75  PRO   X O   1 
ATOM   543  C  CB  . PRO   A 1 89  ? 12.100  22.661  18.518  1.00 61.30  ? 75  PRO   X CB  1 
ATOM   544  C  CG  . PRO   A 1 89  ? 13.541  23.045  18.152  1.00 66.33  ? 75  PRO   X CG  1 
ATOM   545  C  CD  . PRO   A 1 89  ? 14.301  21.729  18.095  1.00 57.44  ? 75  PRO   X CD  1 
ATOM   546  N  N   . GLN   A 1 90  ? 11.707  21.748  15.449  1.00 52.59  ? 76  GLN   X N   1 
ATOM   547  C  CA  . GLN   A 1 90  ? 11.094  21.787  14.077  1.00 56.20  ? 76  GLN   X CA  1 
ATOM   548  C  C   . GLN   A 1 90  ? 11.364  20.477  13.288  1.00 49.66  ? 76  GLN   X C   1 
ATOM   549  O  O   . GLN   A 1 90  ? 11.262  20.497  12.070  1.00 48.15  ? 76  GLN   X O   1 
ATOM   550  C  CB  . GLN   A 1 90  ? 11.685  22.937  13.251  1.00 64.43  ? 76  GLN   X CB  1 
ATOM   551  C  CG  . GLN   A 1 90  ? 11.089  24.305  13.550  1.00 73.57  ? 76  GLN   X CG  1 
ATOM   552  C  CD  . GLN   A 1 90  ? 11.714  24.950  14.760  1.00 85.52  ? 76  GLN   X CD  1 
ATOM   553  O  OE1 . GLN   A 1 90  ? 12.877  24.722  15.093  1.00 85.76  ? 76  GLN   X OE1 1 
ATOM   554  N  NE2 . GLN   A 1 90  ? 10.935  25.781  15.425  1.00 97.71  ? 76  GLN   X NE2 1 
ATOM   555  N  N   . GLY   A 1 91  ? 11.741  19.390  13.954  1.00 48.27  ? 77  GLY   X N   1 
ATOM   556  C  CA  . GLY   A 1 91  ? 12.166  18.150  13.282  1.00 49.12  ? 77  GLY   X CA  1 
ATOM   557  C  C   . GLY   A 1 91  ? 10.970  17.371  12.748  1.00 42.78  ? 77  GLY   X C   1 
ATOM   558  O  O   . GLY   A 1 91  ? 9.882   17.559  13.271  1.00 43.88  ? 77  GLY   X O   1 
ATOM   559  N  N   . ARG   A 1 92  ? 11.192  16.521  11.747  1.00 41.15  ? 78  ARG   X N   1 
ATOM   560  C  CA  . ARG   A 1 92  ? 10.169  15.614  11.154  1.00 41.23  ? 78  ARG   X CA  1 
ATOM   561  C  C   . ARG   A 1 92  ? 9.817   14.494  12.136  1.00 39.73  ? 78  ARG   X C   1 
ATOM   562  O  O   . ARG   A 1 92  ? 8.716   13.971  12.049  1.00 44.12  ? 78  ARG   X O   1 
ATOM   563  C  CB  . ARG   A 1 92  ? 10.705  15.022  9.852   1.00 41.53  ? 78  ARG   X CB  1 
ATOM   564  C  CG  . ARG   A 1 92  ? 10.863  16.036  8.733   1.00 41.53  ? 78  ARG   X CG  1 
ATOM   565  C  CD  . ARG   A 1 92  ? 11.329  15.328  7.501   1.00 39.23  ? 78  ARG   X CD  1 
ATOM   566  N  NE  . ARG   A 1 92  ? 11.545  16.191  6.358   1.00 37.65  ? 78  ARG   X NE  1 
ATOM   567  C  CZ  . ARG   A 1 92  ? 11.940  15.765  5.178   1.00 43.38  ? 78  ARG   X CZ  1 
ATOM   568  N  NH1 . ARG   A 1 92  ? 12.127  14.461  4.970   1.00 39.59  ? 78  ARG   X NH1 1 
ATOM   569  N  NH2 . ARG   A 1 92  ? 12.165  16.634  4.210   1.00 42.53  ? 78  ARG   X NH2 1 
ATOM   570  N  N   . TRP   A 1 93  ? 10.725  14.083  13.007  1.00 38.86  ? 79  TRP   X N   1 
ATOM   571  C  CA  . TRP   A 1 93  ? 10.433  12.984  13.942  1.00 40.59  ? 79  TRP   X CA  1 
ATOM   572  C  C   . TRP   A 1 93  ? 9.554   13.552  15.054  1.00 45.18  ? 79  TRP   X C   1 
ATOM   573  O  O   . TRP   A 1 93  ? 9.859   14.645  15.561  1.00 43.87  ? 79  TRP   X O   1 
ATOM   574  C  CB  . TRP   A 1 93  ? 11.711  12.363  14.498  1.00 39.70  ? 79  TRP   X CB  1 
ATOM   575  C  CG  . TRP   A 1 93  ? 12.560  11.620  13.504  1.00 40.61  ? 79  TRP   X CG  1 
ATOM   576  C  CD1 . TRP   A 1 93  ? 12.393  11.530  12.152  1.00 36.74  ? 79  TRP   X CD1 1 
ATOM   577  C  CD2 . TRP   A 1 93  ? 13.721  10.829  13.804  1.00 38.08  ? 79  TRP   X CD2 1 
ATOM   578  N  NE1 . TRP   A 1 93  ? 13.382  10.767  11.591  1.00 37.64  ? 79  TRP   X NE1 1 
ATOM   579  C  CE2 . TRP   A 1 93  ? 14.205  10.317  12.583  1.00 36.25  ? 79  TRP   X CE2 1 
ATOM   580  C  CE3 . TRP   A 1 93  ? 14.409  10.532  14.976  1.00 40.10  ? 79  TRP   X CE3 1 
ATOM   581  C  CZ2 . TRP   A 1 93  ? 15.354  9.543   12.503  1.00 38.38  ? 79  TRP   X CZ2 1 
ATOM   582  C  CZ3 . TRP   A 1 93  ? 15.514  9.723   14.906  1.00 40.21  ? 79  TRP   X CZ3 1 
ATOM   583  C  CH2 . TRP   A 1 93  ? 15.990  9.253   13.686  1.00 38.88  ? 79  TRP   X CH2 1 
ATOM   584  N  N   . ALA   A 1 94  ? 8.509   12.827  15.420  1.00 44.33  ? 80  ALA   X N   1 
ATOM   585  C  CA  . ALA   A 1 94  ? 7.649   13.115  16.585  1.00 45.12  ? 80  ALA   X CA  1 
ATOM   586  C  C   . ALA   A 1 94  ? 8.525   13.172  17.846  1.00 49.38  ? 80  ALA   X C   1 
ATOM   587  O  O   . ALA   A 1 94  ? 9.561   12.475  17.916  1.00 43.16  ? 80  ALA   X O   1 
ATOM   588  C  CB  . ALA   A 1 94  ? 6.575   12.053  16.693  1.00 45.83  ? 80  ALA   X CB  1 
ATOM   589  N  N   . GLU   A 1 95  ? 8.090   13.918  18.851  1.00 48.73  ? 81  GLU   X N   1 
ATOM   590  C  CA  . GLU   A 1 95  ? 8.866   14.157  20.093  1.00 52.86  ? 81  GLU   X CA  1 
ATOM   591  C  C   . GLU   A 1 95  ? 9.144   12.823  20.793  1.00 45.59  ? 81  GLU   X C   1 
ATOM   592  O  O   . GLU   A 1 95  ? 10.279  12.628  21.211  1.00 49.89  ? 81  GLU   X O   1 
ATOM   593  C  CB  . GLU   A 1 95  ? 8.126   15.173  20.985  1.00 58.40  ? 81  GLU   X CB  1 
ATOM   594  C  CG  . GLU   A 1 95  ? 8.917   15.615  22.217  1.00 66.83  ? 81  GLU   X CG  1 
ATOM   595  C  CD  . GLU   A 1 95  ? 10.338  16.098  21.941  1.00 70.79  ? 81  GLU   X CD  1 
ATOM   596  O  OE1 . GLU   A 1 95  ? 10.546  16.837  20.932  1.00 74.62  ? 81  GLU   X OE1 1 
ATOM   597  O  OE2 . GLU   A 1 95  ? 11.247  15.717  22.718  1.00 70.99  ? 81  GLU   X OE2 1 
ATOM   598  N  N   . SER   A 1 96  ? 8.163   11.931  20.897  1.00 41.92  ? 82  SER   X N   1 
ATOM   599  C  CA  . SER   A 1 96  ? 8.326   10.599  21.520  1.00 44.30  ? 82  SER   X CA  1 
ATOM   600  C  C   . SER   A 1 96  ? 9.397   9.800   20.763  1.00 42.59  ? 82  SER   X C   1 
ATOM   601  O  O   . SER   A 1 96  ? 10.168  9.109   21.408  1.00 43.99  ? 82  SER   X O   1 
ATOM   602  C  CB  . SER   A 1 96  ? 7.009   9.834   21.562  1.00 49.33  ? 82  SER   X CB  1 
ATOM   603  O  OG  . SER   A 1 96  ? 6.514   9.642   20.243  1.00 45.83  ? 82  SER   X OG  1 
ATOM   604  N  N   . THR   A 1 97  ? 9.435   9.881   19.433  1.00 42.45  ? 83  THR   X N   1 
ATOM   605  C  CA  . THR   A 1 97  ? 10.454  9.204   18.594  1.00 42.49  ? 83  THR   X CA  1 
ATOM   606  C  C   . THR   A 1 97  ? 11.854  9.778   18.908  1.00 45.19  ? 83  THR   X C   1 
ATOM   607  O  O   . THR   A 1 97  ? 12.801  9.009   19.143  1.00 41.61  ? 83  THR   X O   1 
ATOM   608  C  CB  . THR   A 1 97  ? 10.091  9.369   17.123  1.00 43.41  ? 83  THR   X CB  1 
ATOM   609  O  OG1 . THR   A 1 97  ? 8.731   8.957   17.005  1.00 38.14  ? 83  THR   X OG1 1 
ATOM   610  C  CG2 . THR   A 1 97  ? 11.003  8.575   16.218  1.00 42.65  ? 83  THR   X CG2 1 
ATOM   611  N  N   . GLN   A 1 98  ? 11.975  11.095  18.979  1.00 40.79  ? 84  GLN   X N   1 
ATOM   612  C  CA  . GLN   A 1 98  ? 13.291  11.749  19.255  1.00 41.04  ? 84  GLN   X CA  1 
ATOM   613  C  C   . GLN   A 1 98  ? 13.834  11.355  20.626  1.00 43.59  ? 84  GLN   X C   1 
ATOM   614  O  O   . GLN   A 1 98  ? 15.070  11.236  20.756  1.00 46.36  ? 84  GLN   X O   1 
ATOM   615  C  CB  . GLN   A 1 98  ? 13.162  13.257  19.214  1.00 40.37  ? 84  GLN   X CB  1 
ATOM   616  C  CG  . GLN   A 1 98  ? 12.777  13.724  17.838  1.00 39.80  ? 84  GLN   X CG  1 
ATOM   617  C  CD  . GLN   A 1 98  ? 12.979  15.214  17.712  1.00 44.89  ? 84  GLN   X CD  1 
ATOM   618  O  OE1 . GLN   A 1 98  ? 13.939  15.770  18.236  1.00 46.74  ? 84  GLN   X OE1 1 
ATOM   619  N  NE2 . GLN   A 1 98  ? 12.113  15.846  16.941  1.00 41.18  ? 84  GLN   X NE2 1 
ATOM   620  N  N   . GLN   A 1 99  ? 12.944  11.065  21.580  1.00 43.87  ? 85  GLN   X N   1 
ATOM   621  C  CA  . GLN   A 1 99  ? 13.326  10.739  22.972  1.00 45.85  ? 85  GLN   X CA  1 
ATOM   622  C  C   . GLN   A 1 99  ? 13.668  9.249   23.117  1.00 45.34  ? 85  GLN   X C   1 
ATOM   623  O  O   . GLN   A 1 99  ? 14.492  8.921   23.996  1.00 44.04  ? 85  GLN   X O   1 
ATOM   624  C  CB  . GLN   A 1 99  ? 12.220  11.225  23.912  1.00 51.61  ? 85  GLN   X CB  1 
ATOM   625  C  CG  . GLN   A 1 99  ? 12.201  12.749  24.063  1.00 65.12  ? 85  GLN   X CG  1 
ATOM   626  C  CD  . GLN   A 1 99  ? 11.398  13.189  25.263  1.00 75.95  ? 85  GLN   X CD  1 
ATOM   627  O  OE1 . GLN   A 1 99  ? 10.457  13.970  25.141  1.00 86.89  ? 85  GLN   X OE1 1 
ATOM   628  N  NE2 . GLN   A 1 99  ? 11.755  12.681  26.435  1.00 80.75  ? 85  GLN   X NE2 1 
ATOM   629  N  N   . MET   A 1 100 ? 13.050  8.361   22.333  1.00 43.49  ? 86  MET   X N   1 
ATOM   630  C  CA  . MET   A 1 100 ? 13.305  6.897   22.440  1.00 42.83  ? 86  MET   X CA  1 
ATOM   631  C  C   . MET   A 1 100 ? 14.435  6.461   21.487  1.00 40.03  ? 86  MET   X C   1 
ATOM   632  O  O   . MET   A 1 100 ? 15.096  5.443   21.792  1.00 39.24  ? 86  MET   X O   1 
ATOM   633  C  CB  . MET   A 1 100 ? 12.040  6.093   22.103  1.00 45.19  ? 86  MET   X CB  1 
ATOM   634  C  CG  . MET   A 1 100 ? 11.096  5.927   23.249  1.00 50.28  ? 86  MET   X CG  1 
ATOM   635  S  SD  . MET   A 1 100 ? 9.748   4.735   22.824  1.00 51.53  ? 86  MET   X SD  1 
ATOM   636  C  CE  . MET   A 1 100 ? 8.799   5.734   21.668  1.00 55.21  ? 86  MET   X CE  1 
ATOM   637  N  N   . PHE   A 1 101 ? 14.641  7.173   20.378  1.00 36.63  ? 87  PHE   X N   1 
ATOM   638  C  CA  . PHE   A 1 101 ? 15.598  6.808   19.296  1.00 38.69  ? 87  PHE   X CA  1 
ATOM   639  C  C   . PHE   A 1 101 ? 16.422  8.022   18.868  1.00 37.95  ? 87  PHE   X C   1 
ATOM   640  O  O   . PHE   A 1 101 ? 16.644  8.236   17.687  1.00 40.07  ? 87  PHE   X O   1 
ATOM   641  C  CB  . PHE   A 1 101 ? 14.853  6.196   18.098  1.00 40.10  ? 87  PHE   X CB  1 
ATOM   642  C  CG  . PHE   A 1 101 ? 13.885  5.100   18.482  1.00 41.54  ? 87  PHE   X CG  1 
ATOM   643  C  CD1 . PHE   A 1 101 ? 14.342  3.831   18.805  1.00 44.43  ? 87  PHE   X CD1 1 
ATOM   644  C  CD2 . PHE   A 1 101 ? 12.511  5.337   18.514  1.00 47.33  ? 87  PHE   X CD2 1 
ATOM   645  C  CE1 . PHE   A 1 101 ? 13.456  2.829   19.182  1.00 48.84  ? 87  PHE   X CE1 1 
ATOM   646  C  CE2 . PHE   A 1 101 ? 11.619  4.328   18.859  1.00 48.63  ? 87  PHE   X CE2 1 
ATOM   647  C  CZ  . PHE   A 1 101 ? 12.097  3.075   19.204  1.00 50.19  ? 87  PHE   X CZ  1 
ATOM   648  N  N   . PRO   A 1 102 ? 16.982  8.827   19.807  1.00 38.81  ? 88  PRO   X N   1 
ATOM   649  C  CA  . PRO   A 1 102 ? 17.739  10.019  19.415  1.00 39.62  ? 88  PRO   X CA  1 
ATOM   650  C  C   . PRO   A 1 102 ? 18.889  9.689   18.450  1.00 34.88  ? 88  PRO   X C   1 
ATOM   651  O  O   . PRO   A 1 102 ? 19.696  8.799   18.713  1.00 38.68  ? 88  PRO   X O   1 
ATOM   652  C  CB  . PRO   A 1 102 ? 18.282  10.590  20.751  1.00 39.90  ? 88  PRO   X CB  1 
ATOM   653  C  CG  . PRO   A 1 102 ? 18.253  9.391   21.692  1.00 46.81  ? 88  PRO   X CG  1 
ATOM   654  C  CD  . PRO   A 1 102 ? 17.023  8.583   21.256  1.00 42.59  ? 88  PRO   X CD  1 
ATOM   655  N  N   . TRP   A 1 103 ? 18.972  10.450  17.364  1.00 35.77  ? 89  TRP   X N   1 
ATOM   656  C  CA  . TRP   A 1 103 ? 20.077  10.385  16.376  1.00 38.97  ? 89  TRP   X CA  1 
ATOM   657  C  C   . TRP   A 1 103 ? 21.055  11.549  16.618  1.00 43.31  ? 89  TRP   X C   1 
ATOM   658  O  O   . TRP   A 1 103 ? 20.601  12.701  16.672  1.00 38.15  ? 89  TRP   X O   1 
ATOM   659  C  CB  . TRP   A 1 103 ? 19.489  10.508  14.978  1.00 36.23  ? 89  TRP   X CB  1 
ATOM   660  C  CG  . TRP   A 1 103 ? 20.479  10.454  13.861  1.00 36.63  ? 89  TRP   X CG  1 
ATOM   661  C  CD1 . TRP   A 1 103 ? 21.501  9.576   13.707  1.00 36.13  ? 89  TRP   X CD1 1 
ATOM   662  C  CD2 . TRP   A 1 103 ? 20.474  11.276  12.686  1.00 38.68  ? 89  TRP   X CD2 1 
ATOM   663  N  NE1 . TRP   A 1 103 ? 22.148  9.809   12.535  1.00 36.04  ? 89  TRP   X NE1 1 
ATOM   664  C  CE2 . TRP   A 1 103 ? 21.540  10.847  11.880  1.00 36.25  ? 89  TRP   X CE2 1 
ATOM   665  C  CE3 . TRP   A 1 103 ? 19.727  12.386  12.281  1.00 39.28  ? 89  TRP   X CE3 1 
ATOM   666  C  CZ2 . TRP   A 1 103 ? 21.862  11.465  10.671  1.00 38.73  ? 89  TRP   X CZ2 1 
ATOM   667  C  CZ3 . TRP   A 1 103 ? 20.019  12.966  11.073  1.00 37.90  ? 89  TRP   X CZ3 1 
ATOM   668  C  CH2 . TRP   A 1 103 ? 21.078  12.517  10.278  1.00 36.99  ? 89  TRP   X CH2 1 
ATOM   669  N  N   . THR   A 1 104 ? 22.342  11.278  16.676  1.00 39.99  ? 90  THR   X N   1 
ATOM   670  C  CA  . THR   A 1 104 ? 23.360  12.368  16.794  1.00 46.24  ? 90  THR   X CA  1 
ATOM   671  C  C   . THR   A 1 104 ? 24.269  12.266  15.579  1.00 45.22  ? 90  THR   X C   1 
ATOM   672  O  O   . THR   A 1 104 ? 24.784  11.152  15.291  1.00 43.28  ? 90  THR   X O   1 
ATOM   673  C  CB  . THR   A 1 104 ? 24.162  12.269  18.098  1.00 45.90  ? 90  THR   X CB  1 
ATOM   674  O  OG1 . THR   A 1 104 ? 24.795  11.004  18.044  1.00 51.54  ? 90  THR   X OG1 1 
ATOM   675  C  CG2 . THR   A 1 104 ? 23.339  12.284  19.361  1.00 50.40  ? 90  THR   X CG2 1 
ATOM   676  N  N   . ALA   A 1 105 ? 24.464  13.377  14.891  1.00 44.43  ? 91  ALA   X N   1 
ATOM   677  C  CA  . ALA   A 1 105 ? 25.307  13.440  13.689  1.00 50.51  ? 91  ALA   X CA  1 
ATOM   678  C  C   . ALA   A 1 105 ? 25.874  14.852  13.546  1.00 48.43  ? 91  ALA   X C   1 
ATOM   679  O  O   . ALA   A 1 105 ? 25.100  15.801  13.588  1.00 46.98  ? 91  ALA   X O   1 
ATOM   680  C  CB  . ALA   A 1 105 ? 24.466  13.065  12.493  1.00 52.71  ? 91  ALA   X CB  1 
ATOM   681  N  N   . THR   A 1 106 ? 27.156  14.948  13.273  1.00 48.15  ? 92  THR   X N   1 
ATOM   682  C  CA  . THR   A 1 106 ? 27.812  16.195  12.793  1.00 54.25  ? 92  THR   X CA  1 
ATOM   683  C  C   . THR   A 1 106 ? 27.430  16.379  11.318  1.00 57.65  ? 92  THR   X C   1 
ATOM   684  O  O   . THR   A 1 106 ? 27.033  15.345  10.670  1.00 50.21  ? 92  THR   X O   1 
ATOM   685  C  CB  . THR   A 1 106 ? 29.320  16.077  13.041  1.00 58.45  ? 92  THR   X CB  1 
ATOM   686  O  OG1 . THR   A 1 106 ? 29.812  14.981  12.275  1.00 57.43  ? 92  THR   X OG1 1 
ATOM   687  C  CG2 . THR   A 1 106 ? 29.670  15.839  14.498  1.00 56.01  ? 92  THR   X CG2 1 
ATOM   688  N  N   . GLU   A 1 107 ? 27.522  17.599  10.768  1.00 46.93  ? 93  GLU   X N   1 
ATOM   689  C  CA  . GLU   A 1 107 ? 27.160  17.841  9.340   1.00 52.46  ? 93  GLU   X CA  1 
ATOM   690  C  C   . GLU   A 1 107 ? 27.947  16.917  8.406   1.00 46.87  ? 93  GLU   X C   1 
ATOM   691  O  O   . GLU   A 1 107 ? 27.407  16.610  7.287   1.00 42.58  ? 93  GLU   X O   1 
ATOM   692  C  CB  . GLU   A 1 107 ? 27.393  19.283  8.895   1.00 61.37  ? 93  GLU   X CB  1 
ATOM   693  C  CG  . GLU   A 1 107 ? 26.119  20.111  8.954   1.00 78.04  ? 93  GLU   X CG  1 
ATOM   694  C  CD  . GLU   A 1 107 ? 26.294  21.593  8.690   1.00 94.27  ? 93  GLU   X CD  1 
ATOM   695  O  OE1 . GLU   A 1 107 ? 27.401  22.128  8.945   1.00 107.92 ? 93  GLU   X OE1 1 
ATOM   696  O  OE2 . GLU   A 1 107 ? 25.317  22.207  8.230   1.00 112.79 ? 93  GLU   X OE2 1 
ATOM   697  N  N   . GLU   A 1 108 ? 29.184  16.541  8.765   1.00 44.35  ? 94  GLU   X N   1 
ATOM   698  C  CA  . GLU   A 1 108 ? 30.018  15.670  7.881   1.00 48.62  ? 94  GLU   X CA  1 
ATOM   699  C  C   . GLU   A 1 108 ? 29.363  14.260  7.749   1.00 42.68  ? 94  GLU   X C   1 
ATOM   700  O  O   . GLU   A 1 108 ? 29.659  13.550  6.757   1.00 39.80  ? 94  GLU   X O   1 
ATOM   701  C  CB  . GLU   A 1 108 ? 31.471  15.630  8.356   1.00 55.32  ? 94  GLU   X CB  1 
ATOM   702  C  CG  . GLU   A 1 108 ? 31.665  15.072  9.754   1.00 74.85  ? 94  GLU   X CG  1 
ATOM   703  C  CD  . GLU   A 1 108 ? 33.049  14.499  10.062  1.00 91.10  ? 94  GLU   X CD  1 
ATOM   704  O  OE1 . GLU   A 1 108 ? 33.306  14.177  11.255  1.00 92.24  ? 94  GLU   X OE1 1 
ATOM   705  O  OE2 . GLU   A 1 108 ? 33.864  14.349  9.115   1.00 92.24  ? 94  GLU   X OE2 1 
ATOM   706  N  N   . CYS   A 1 109 ? 28.468  13.908  8.677   1.00 40.01  ? 95  CYS   X N   1 
ATOM   707  C  CA  . CYS   A 1 109 ? 27.785  12.590  8.762   1.00 45.35  ? 95  CYS   X CA  1 
ATOM   708  C  C   . CYS   A 1 109 ? 26.549  12.561  7.865   1.00 41.81  ? 95  CYS   X C   1 
ATOM   709  O  O   . CYS   A 1 109 ? 26.119  11.414  7.535   1.00 42.03  ? 95  CYS   X O   1 
ATOM   710  C  CB  . CYS   A 1 109 ? 27.367  12.243  10.184  1.00 44.27  ? 95  CYS   X CB  1 
ATOM   711  S  SG  . CYS   A 1 109 ? 28.753  11.739  11.232  1.00 52.73  ? 95  CYS   X SG  1 
ATOM   712  N  N   . TYR   A 1 110 ? 26.027  13.714  7.420   1.00 39.31  ? 96  TYR   X N   1 
ATOM   713  C  CA  . TYR   A 1 110 ? 24.808  13.705  6.560   1.00 43.28  ? 96  TYR   X CA  1 
ATOM   714  C  C   . TYR   A 1 110 ? 25.169  13.005  5.257   1.00 43.40  ? 96  TYR   X C   1 
ATOM   715  O  O   . TYR   A 1 110 ? 26.262  13.224  4.743   1.00 40.92  ? 96  TYR   X O   1 
ATOM   716  C  CB  . TYR   A 1 110 ? 24.209  15.087  6.292   1.00 41.19  ? 96  TYR   X CB  1 
ATOM   717  C  CG  . TYR   A 1 110 ? 23.771  15.838  7.523   1.00 48.40  ? 96  TYR   X CG  1 
ATOM   718  C  CD1 . TYR   A 1 110 ? 23.406  15.168  8.678   1.00 48.42  ? 96  TYR   X CD1 1 
ATOM   719  C  CD2 . TYR   A 1 110 ? 23.689  17.223  7.524   1.00 52.09  ? 96  TYR   X CD2 1 
ATOM   720  C  CE1 . TYR   A 1 110 ? 23.004  15.853  9.815   1.00 52.74  ? 96  TYR   X CE1 1 
ATOM   721  C  CE2 . TYR   A 1 110 ? 23.272  17.922  8.645   1.00 47.51  ? 96  TYR   X CE2 1 
ATOM   722  C  CZ  . TYR   A 1 110 ? 22.946  17.232  9.795   1.00 51.49  ? 96  TYR   X CZ  1 
ATOM   723  O  OH  . TYR   A 1 110 ? 22.512  17.874  10.901  1.00 54.58  ? 96  TYR   X OH  1 
ATOM   724  N  N   . LEU   A 1 111 ? 24.280  12.143  4.753   1.00 40.63  ? 97  LEU   X N   1 
ATOM   725  C  CA  . LEU   A 1 111 ? 24.585  11.352  3.535   1.00 40.65  ? 97  LEU   X CA  1 
ATOM   726  C  C   . LEU   A 1 111 ? 24.990  12.274  2.371   1.00 38.67  ? 97  LEU   X C   1 
ATOM   727  O  O   . LEU   A 1 111 ? 25.936  11.923  1.666   1.00 36.20  ? 97  LEU   X O   1 
ATOM   728  C  CB  . LEU   A 1 111 ? 23.375  10.488  3.161   1.00 39.75  ? 97  LEU   X CB  1 
ATOM   729  C  CG  . LEU   A 1 111 ? 23.537  9.671   1.884   1.00 37.81  ? 97  LEU   X CG  1 
ATOM   730  C  CD1 . LEU   A 1 111 ? 24.675  8.653   2.021   1.00 39.64  ? 97  LEU   X CD1 1 
ATOM   731  C  CD2 . LEU   A 1 111 ? 22.195  8.971   1.569   1.00 41.55  ? 97  LEU   X CD2 1 
ATOM   732  N  N   . HIS   A 1 112 ? 24.291  13.393  2.158   1.00 38.85  ? 98  HIS   X N   1 
ATOM   733  C  CA  . HIS   A 1 112 ? 24.590  14.361  1.063   1.00 42.20  ? 98  HIS   X CA  1 
ATOM   734  C  C   . HIS   A 1 112 ? 26.087  14.778  1.112   1.00 34.99  ? 98  HIS   X C   1 
ATOM   735  O  O   . HIS   A 1 112 ? 26.737  14.775  0.069   1.00 39.69  ? 98  HIS   X O   1 
ATOM   736  C  CB  . HIS   A 1 112 ? 23.651  15.596  1.144   1.00 53.18  ? 98  HIS   X CB  1 
ATOM   737  C  CG  . HIS   A 1 112 ? 23.860  16.541  0.005   1.00 77.41  ? 98  HIS   X CG  1 
ATOM   738  N  ND1 . HIS   A 1 112 ? 23.099  16.476  -1.165  1.00 95.70  ? 98  HIS   X ND1 1 
ATOM   739  C  CD2 . HIS   A 1 112 ? 24.784  17.510  -0.202  1.00 88.63  ? 98  HIS   X CD2 1 
ATOM   740  C  CE1 . HIS   A 1 112 ? 23.524  17.382  -2.026  1.00 88.55  ? 98  HIS   X CE1 1 
ATOM   741  N  NE2 . HIS   A 1 112 ? 24.563  18.027  -1.459  1.00 99.18  ? 98  HIS   X NE2 1 
ATOM   742  N  N   . ASN   A 1 113 ? 26.596  15.064  2.300   1.00 36.92  ? 99  ASN   X N   1 
ATOM   743  C  CA  . ASN   A 1 113 ? 28.014  15.478  2.497   1.00 43.01  ? 99  ASN   X CA  1 
ATOM   744  C  C   . ASN   A 1 113 ? 28.969  14.286  2.320   1.00 45.39  ? 99  ASN   X C   1 
ATOM   745  O  O   . ASN   A 1 113 ? 30.008  14.472  1.639   1.00 42.00  ? 99  ASN   X O   1 
ATOM   746  C  CB  . ASN   A 1 113 ? 28.194  16.183  3.828   1.00 37.89  ? 99  ASN   X CB  1 
ATOM   747  C  CG  . ASN   A 1 113 ? 27.424  17.484  3.844   1.00 43.17  ? 99  ASN   X CG  1 
ATOM   748  O  OD1 . ASN   A 1 113 ? 27.225  18.079  2.792   1.00 47.42  ? 99  ASN   X OD1 1 
ATOM   749  N  ND2 . ASN   A 1 113 ? 26.969  17.896  5.012   1.00 47.68  ? 99  ASN   X ND2 1 
ATOM   750  N  N   . ARG   A 1 114 ? 28.642  13.106  2.865   1.00 43.51  ? 100 ARG   X N   1 
ATOM   751  C  CA  . ARG   A 1 114 ? 29.507  11.906  2.699   1.00 40.08  ? 100 ARG   X CA  1 
ATOM   752  C  C   . ARG   A 1 114 ? 29.668  11.646  1.211   1.00 39.45  ? 100 ARG   X C   1 
ATOM   753  O  O   . ARG   A 1 114 ? 30.802  11.369  0.753   1.00 40.08  ? 100 ARG   X O   1 
ATOM   754  C  CB  . ARG   A 1 114 ? 28.913  10.674  3.393   1.00 41.11  ? 100 ARG   X CB  1 
ATOM   755  C  CG  . ARG   A 1 114 ? 28.972  10.733  4.905   1.00 40.37  ? 100 ARG   X CG  1 
ATOM   756  C  CD  . ARG   A 1 114 ? 30.407  10.599  5.423   1.00 41.01  ? 100 ARG   X CD  1 
ATOM   757  N  NE  . ARG   A 1 114 ? 30.459  10.532  6.885   1.00 38.57  ? 100 ARG   X NE  1 
ATOM   758  C  CZ  . ARG   A 1 114 ? 31.477  10.992  7.615   1.00 42.07  ? 100 ARG   X CZ  1 
ATOM   759  N  NH1 . ARG   A 1 114 ? 32.546  11.500  7.011   1.00 44.89  ? 100 ARG   X NH1 1 
ATOM   760  N  NH2 . ARG   A 1 114 ? 31.459  10.863  8.916   1.00 40.26  ? 100 ARG   X NH2 1 
ATOM   761  N  N   . LEU   A 1 115 ? 28.588  11.742  0.431   1.00 40.93  ? 101 LEU   X N   1 
ATOM   762  C  CA  . LEU   A 1 115 ? 28.674  11.444  -1.027  1.00 37.44  ? 101 LEU   X CA  1 
ATOM   763  C  C   . LEU   A 1 115 ? 29.476  12.570  -1.750  1.00 40.08  ? 101 LEU   X C   1 
ATOM   764  O  O   . LEU   A 1 115 ? 30.263  12.250  -2.675  1.00 41.61  ? 101 LEU   X O   1 
ATOM   765  C  CB  . LEU   A 1 115 ? 27.281  11.309  -1.640  1.00 38.32  ? 101 LEU   X CB  1 
ATOM   766  C  CG  . LEU   A 1 115 ? 26.473  10.074  -1.209  1.00 37.34  ? 101 LEU   X CG  1 
ATOM   767  C  CD1 . LEU   A 1 115 ? 25.017  10.195  -1.673  1.00 39.95  ? 101 LEU   X CD1 1 
ATOM   768  C  CD2 . LEU   A 1 115 ? 27.106  8.834   -1.786  1.00 36.63  ? 101 LEU   X CD2 1 
ATOM   769  N  N   . GLU   A 1 116 ? 29.218  13.831  -1.432  1.00 39.79  ? 102 GLU   X N   1 
ATOM   770  C  CA  . GLU   A 1 116 ? 29.951  14.997  -2.023  1.00 48.68  ? 102 GLU   X CA  1 
ATOM   771  C  C   . GLU   A 1 116 ? 31.479  14.819  -1.835  1.00 43.96  ? 102 GLU   X C   1 
ATOM   772  O  O   . GLU   A 1 116 ? 32.223  15.069  -2.802  1.00 41.98  ? 102 GLU   X O   1 
ATOM   773  C  CB  . GLU   A 1 116 ? 29.453  16.283  -1.372  1.00 52.55  ? 102 GLU   X CB  1 
ATOM   774  C  CG  . GLU   A 1 116 ? 30.128  17.551  -1.879  1.00 59.70  ? 102 GLU   X CG  1 
ATOM   775  C  CD  . GLU   A 1 116 ? 29.569  18.798  -1.200  1.00 79.43  ? 102 GLU   X CD  1 
ATOM   776  O  OE1 . GLU   A 1 116 ? 28.582  18.675  -0.427  1.00 88.71  ? 102 GLU   X OE1 1 
ATOM   777  O  OE2 . GLU   A 1 116 ? 30.110  19.893  -1.436  1.00 96.00  ? 102 GLU   X OE2 1 
ATOM   778  N  N   . GLN   A 1 117 ? 31.922  14.324  -0.678  1.00 44.39  ? 103 GLN   X N   1 
ATOM   779  C  CA  . GLN   A 1 117 ? 33.363  14.107  -0.365  1.00 43.64  ? 103 GLN   X CA  1 
ATOM   780  C  C   . GLN   A 1 117 ? 33.917  13.014  -1.269  1.00 47.42  ? 103 GLN   X C   1 
ATOM   781  O  O   . GLN   A 1 117 ? 35.136  12.972  -1.445  1.00 47.03  ? 103 GLN   X O   1 
ATOM   782  C  CB  . GLN   A 1 117 ? 33.590  13.807  1.115   1.00 44.71  ? 103 GLN   X CB  1 
ATOM   783  C  CG  . GLN   A 1 117 ? 33.513  15.045  1.996   1.00 45.09  ? 103 GLN   X CG  1 
ATOM   784  C  CD  . GLN   A 1 117 ? 34.392  16.164  1.474   1.00 54.11  ? 103 GLN   X CD  1 
ATOM   785  O  OE1 . GLN   A 1 117 ? 33.908  17.244  1.129   1.00 56.06  ? 103 GLN   X OE1 1 
ATOM   786  N  NE2 . GLN   A 1 117 ? 35.688  15.910  1.398   1.00 52.32  ? 103 GLN   X NE2 1 
ATOM   787  N  N   . LEU   A 1 118 ? 33.063  12.173  -1.854  1.00 40.27  ? 104 LEU   X N   1 
ATOM   788  C  CA  . LEU   A 1 118 ? 33.498  11.168  -2.859  1.00 40.06  ? 104 LEU   X CA  1 
ATOM   789  C  C   . LEU   A 1 118 ? 33.270  11.713  -4.272  1.00 36.18  ? 104 LEU   X C   1 
ATOM   790  O  O   . LEU   A 1 118 ? 33.471  10.941  -5.224  1.00 40.24  ? 104 LEU   X O   1 
ATOM   791  C  CB  . LEU   A 1 118 ? 32.744  9.849   -2.632  1.00 38.98  ? 104 LEU   X CB  1 
ATOM   792  C  CG  . LEU   A 1 118 ? 32.893  9.248   -1.238  1.00 39.53  ? 104 LEU   X CG  1 
ATOM   793  C  CD1 . LEU   A 1 118 ? 31.973  8.037   -1.032  1.00 41.46  ? 104 LEU   X CD1 1 
ATOM   794  C  CD2 . LEU   A 1 118 ? 34.346  8.848   -0.988  1.00 44.34  ? 104 LEU   X CD2 1 
ATOM   795  N  N   . LYS   A 1 119 ? 32.888  12.993  -4.418  1.00 41.17  ? 105 LYS   X N   1 
ATOM   796  C  CA  . LYS   A 1 119 ? 32.569  13.620  -5.740  1.00 45.80  ? 105 LYS   X CA  1 
ATOM   797  C  C   . LYS   A 1 119 ? 31.358  12.896  -6.372  1.00 41.44  ? 105 LYS   X C   1 
ATOM   798  O  O   . LYS   A 1 119 ? 31.323  12.705  -7.594  1.00 38.40  ? 105 LYS   X O   1 
ATOM   799  C  CB  . LYS   A 1 119 ? 33.796  13.657  -6.667  1.00 55.16  ? 105 LYS   X CB  1 
ATOM   800  C  CG  . LYS   A 1 119 ? 34.998  14.470  -6.167  1.00 61.71  ? 105 LYS   X CG  1 
ATOM   801  C  CD  . LYS   A 1 119 ? 36.195  13.628  -5.673  1.00 85.43  ? 105 LYS   X CD  1 
ATOM   802  C  CE  . LYS   A 1 119 ? 37.559  14.061  -6.202  1.00 92.53  ? 105 LYS   X CE  1 
ATOM   803  N  NZ  . LYS   A 1 119 ? 37.902  13.433  -7.504  1.00 99.13  ? 105 LYS   X NZ  1 
ATOM   804  N  N   . VAL   A 1 120 ? 30.401  12.472  -5.544  1.00 41.17  ? 106 VAL   X N   1 
ATOM   805  C  CA  . VAL   A 1 120 ? 29.182  11.730  -6.003  1.00 45.40  ? 106 VAL   X CA  1 
ATOM   806  C  C   . VAL   A 1 120 ? 28.007  12.654  -5.714  1.00 40.62  ? 106 VAL   X C   1 
ATOM   807  O  O   . VAL   A 1 120 ? 27.830  13.025  -4.543  1.00 44.63  ? 106 VAL   X O   1 
ATOM   808  C  CB  . VAL   A 1 120 ? 29.005  10.356  -5.323  1.00 42.52  ? 106 VAL   X CB  1 
ATOM   809  C  CG1 . VAL   A 1 120 ? 27.686  9.679   -5.769  1.00 43.22  ? 106 VAL   X CG1 1 
ATOM   810  C  CG2 . VAL   A 1 120 ? 30.190  9.436   -5.593  1.00 41.58  ? 106 VAL   X CG2 1 
ATOM   811  N  N   . ARG   A 1 121 ? 27.340  13.093  -6.779  1.00 41.21  ? 107 ARG   X N   1 
ATOM   812  C  CA  . ARG   A 1 121 ? 26.080  13.877  -6.700  1.00 51.70  ? 107 ARG   X CA  1 
ATOM   813  C  C   . ARG   A 1 121 ? 24.886  12.921  -6.573  1.00 42.63  ? 107 ARG   X C   1 
ATOM   814  O  O   . ARG   A 1 121 ? 24.911  11.839  -7.149  1.00 41.29  ? 107 ARG   X O   1 
ATOM   815  C  CB  . ARG   A 1 121 ? 25.944  14.709  -7.975  1.00 53.75  ? 107 ARG   X CB  1 
ATOM   816  C  CG  . ARG   A 1 121 ? 27.065  15.722  -8.184  1.00 68.64  ? 107 ARG   X CG  1 
ATOM   817  C  CD  . ARG   A 1 121 ? 26.573  16.997  -8.839  1.00 81.79  ? 107 ARG   X CD  1 
ATOM   818  N  NE  . ARG   A 1 121 ? 25.365  17.462  -8.155  1.00 102.92 ? 107 ARG   X NE  1 
ATOM   819  C  CZ  . ARG   A 1 121 ? 24.588  18.473  -8.538  1.00 114.31 ? 107 ARG   X CZ  1 
ATOM   820  N  NH1 . ARG   A 1 121 ? 23.513  18.767  -7.821  1.00 112.73 ? 107 ARG   X NH1 1 
ATOM   821  N  NH2 . ARG   A 1 121 ? 24.886  19.185  -9.617  1.00 111.39 ? 107 ARG   X NH2 1 
ATOM   822  N  N   . PRO   A 1 122 ? 23.786  13.328  -5.908  1.00 47.16  ? 108 PRO   X N   1 
ATOM   823  C  CA  . PRO   A 1 122 ? 22.572  12.503  -5.860  1.00 48.10  ? 108 PRO   X CA  1 
ATOM   824  C  C   . PRO   A 1 122 ? 22.159  11.981  -7.237  1.00 47.51  ? 108 PRO   X C   1 
ATOM   825  O  O   . PRO   A 1 122 ? 21.876  10.816  -7.368  1.00 45.58  ? 108 PRO   X O   1 
ATOM   826  C  CB  . PRO   A 1 122 ? 21.539  13.482  -5.306  1.00 46.55  ? 108 PRO   X CB  1 
ATOM   827  C  CG  . PRO   A 1 122 ? 22.376  14.356  -4.366  1.00 50.41  ? 108 PRO   X CG  1 
ATOM   828  C  CD  . PRO   A 1 122 ? 23.658  14.582  -5.126  1.00 45.03  ? 108 PRO   X CD  1 
ATOM   829  N  N   . GLU   A 1 123 ? 22.205  12.844  -8.256  1.00 46.28  ? 109 GLU   X N   1 
ATOM   830  C  CA  . GLU   A 1 123 ? 21.822  12.468  -9.641  1.00 44.51  ? 109 GLU   X CA  1 
ATOM   831  C  C   . GLU   A 1 123 ? 22.733  11.371  -10.196 1.00 44.00  ? 109 GLU   X C   1 
ATOM   832  O  O   . GLU   A 1 123 ? 22.346  10.775  -11.187 1.00 42.72  ? 109 GLU   X O   1 
ATOM   833  C  CB  . GLU   A 1 123 ? 21.821  13.691  -10.563 1.00 55.22  ? 109 GLU   X CB  1 
ATOM   834  C  CG  . GLU   A 1 123 ? 23.214  14.168  -10.931 1.00 58.78  ? 109 GLU   X CG  1 
ATOM   835  C  CD  . GLU   A 1 123 ? 23.236  15.560  -11.520 1.00 69.67  ? 109 GLU   X CD  1 
ATOM   836  O  OE1 . GLU   A 1 123 ? 23.003  15.682  -12.734 1.00 75.79  ? 109 GLU   X OE1 1 
ATOM   837  O  OE2 . GLU   A 1 123 ? 23.471  16.507  -10.748 1.00 75.11  ? 109 GLU   X OE2 1 
ATOM   838  N  N   . ASP   A 1 124 ? 23.924  11.118  -9.642  1.00 45.46  ? 110 ASP   X N   1 
ATOM   839  C  CA  . ASP   A 1 124 ? 24.816  10.042  -10.180 1.00 46.68  ? 110 ASP   X CA  1 
ATOM   840  C  C   . ASP   A 1 124 ? 24.379  8.641   -9.681  1.00 42.07  ? 110 ASP   X C   1 
ATOM   841  O  O   . ASP   A 1 124 ? 24.977  7.642   -10.119 1.00 41.31  ? 110 ASP   X O   1 
ATOM   842  C  CB  . ASP   A 1 124 ? 26.292  10.308  -9.834  1.00 46.25  ? 110 ASP   X CB  1 
ATOM   843  C  CG  . ASP   A 1 124 ? 26.817  11.654  -10.322 1.00 56.16  ? 110 ASP   X CG  1 
ATOM   844  O  OD1 . ASP   A 1 124 ? 26.401  12.070  -11.432 1.00 55.27  ? 110 ASP   X OD1 1 
ATOM   845  O  OD2 . ASP   A 1 124 ? 27.612  12.286  -9.569  1.00 53.24  ? 110 ASP   X OD2 1 
ATOM   846  N  N   . ILE   A 1 125 ? 23.402  8.541   -8.789  1.00 40.52  ? 111 ILE   X N   1 
ATOM   847  C  CA  . ILE   A 1 125 ? 22.962  7.207   -8.262  1.00 42.82  ? 111 ILE   X CA  1 
ATOM   848  C  C   . ILE   A 1 125 ? 21.952  6.604   -9.236  1.00 38.73  ? 111 ILE   X C   1 
ATOM   849  O  O   . ILE   A 1 125 ? 20.925  7.214   -9.485  1.00 44.18  ? 111 ILE   X O   1 
ATOM   850  C  CB  . ILE   A 1 125 ? 22.419  7.300   -6.822  1.00 42.51  ? 111 ILE   X CB  1 
ATOM   851  C  CG1 . ILE   A 1 125 ? 23.413  7.978   -5.874  1.00 38.73  ? 111 ILE   X CG1 1 
ATOM   852  C  CG2 . ILE   A 1 125 ? 22.021  5.914   -6.318  1.00 40.77  ? 111 ILE   X CG2 1 
ATOM   853  C  CD1 . ILE   A 1 125 ? 24.743  7.289   -5.752  1.00 35.52  ? 111 ILE   X CD1 1 
ATOM   854  N  N   . ARG   A 1 126 ? 22.267  5.446   -9.795  1.00 37.22  ? 112 ARG   X N   1 
ATOM   855  C  CA  . ARG   A 1 126 ? 21.365  4.691   -10.699 1.00 41.15  ? 112 ARG   X CA  1 
ATOM   856  C  C   . ARG   A 1 126 ? 20.334  3.880   -9.885  1.00 43.59  ? 112 ARG   X C   1 
ATOM   857  O  O   . ARG   A 1 126 ? 19.135  3.844   -10.302 1.00 38.55  ? 112 ARG   X O   1 
ATOM   858  C  CB  . ARG   A 1 126 ? 22.179  3.718   -11.542 1.00 41.20  ? 112 ARG   X CB  1 
ATOM   859  C  CG  . ARG   A 1 126 ? 21.364  3.002   -12.603 1.00 44.39  ? 112 ARG   X CG  1 
ATOM   860  C  CD  . ARG   A 1 126 ? 22.188  2.021   -13.409 1.00 49.27  ? 112 ARG   X CD  1 
ATOM   861  N  NE  . ARG   A 1 126 ? 21.400  1.413   -14.474 1.00 59.60  ? 112 ARG   X NE  1 
ATOM   862  C  CZ  . ARG   A 1 126 ? 21.716  0.304   -15.133 1.00 56.95  ? 112 ARG   X CZ  1 
ATOM   863  N  NH1 . ARG   A 1 126 ? 22.830  -0.349  -14.867 1.00 57.72  ? 112 ARG   X NH1 1 
ATOM   864  N  NH2 . ARG   A 1 126 ? 20.906  -0.158  -16.065 1.00 61.43  ? 112 ARG   X NH2 1 
ATOM   865  N  N   . TYR   A 1 127 ? 20.786  3.185   -8.829  1.00 38.65  ? 113 TYR   X N   1 
ATOM   866  C  CA  . TYR   A 1 127 ? 19.915  2.336   -7.970  1.00 37.92  ? 113 TYR   X CA  1 
ATOM   867  C  C   . TYR   A 1 127 ? 20.115  2.676   -6.499  1.00 36.84  ? 113 TYR   X C   1 
ATOM   868  O  O   . TYR   A 1 127 ? 21.246  2.761   -6.036  1.00 36.15  ? 113 TYR   X O   1 
ATOM   869  C  CB  . TYR   A 1 127 ? 20.226  0.856   -8.160  1.00 35.39  ? 113 TYR   X CB  1 
ATOM   870  C  CG  . TYR   A 1 127 ? 19.941  0.334   -9.533  1.00 37.61  ? 113 TYR   X CG  1 
ATOM   871  C  CD1 . TYR   A 1 127 ? 18.641  0.331   -10.027 1.00 41.84  ? 113 TYR   X CD1 1 
ATOM   872  C  CD2 . TYR   A 1 127 ? 20.950  -0.188  -10.327 1.00 39.09  ? 113 TYR   X CD2 1 
ATOM   873  C  CE1 . TYR   A 1 127 ? 18.342  -0.189  -11.282 1.00 43.72  ? 113 TYR   X CE1 1 
ATOM   874  C  CE2 . TYR   A 1 127 ? 20.678  -0.689  -11.585 1.00 43.72  ? 113 TYR   X CE2 1 
ATOM   875  C  CZ  . TYR   A 1 127 ? 19.371  -0.703  -12.052 1.00 47.57  ? 113 TYR   X CZ  1 
ATOM   876  O  OH  . TYR   A 1 127 ? 19.112  -1.240  -13.267 1.00 50.19  ? 113 TYR   X OH  1 
ATOM   877  N  N   . VAL   A 1 128 ? 19.004  2.772   -5.787  1.00 35.07  ? 114 VAL   X N   1 
ATOM   878  C  CA  . VAL   A 1 128 ? 18.957  2.803   -4.307  1.00 34.10  ? 114 VAL   X CA  1 
ATOM   879  C  C   . VAL   A 1 128 ? 18.241  1.524   -3.870  1.00 36.07  ? 114 VAL   X C   1 
ATOM   880  O  O   . VAL   A 1 128 ? 17.123  1.272   -4.373  1.00 35.15  ? 114 VAL   X O   1 
ATOM   881  C  CB  . VAL   A 1 128 ? 18.259  4.057   -3.770  1.00 35.67  ? 114 VAL   X CB  1 
ATOM   882  C  CG1 . VAL   A 1 128 ? 18.327  4.093   -2.263  1.00 36.86  ? 114 VAL   X CG1 1 
ATOM   883  C  CG2 . VAL   A 1 128 ? 18.850  5.330   -4.349  1.00 40.30  ? 114 VAL   X CG2 1 
ATOM   884  N  N   . VAL   A 1 129 ? 18.908  0.703   -3.076  1.00 32.90  ? 115 VAL   X N   1 
ATOM   885  C  CA  . VAL   A 1 129 ? 18.254  -0.473  -2.444  1.00 35.28  ? 115 VAL   X CA  1 
ATOM   886  C  C   . VAL   A 1 129 ? 17.847  -0.038  -1.035  1.00 34.35  ? 115 VAL   X C   1 
ATOM   887  O  O   . VAL   A 1 129 ? 18.696  0.209   -0.225  1.00 32.13  ? 115 VAL   X O   1 
ATOM   888  C  CB  . VAL   A 1 129 ? 19.148  -1.725  -2.491  1.00 33.80  ? 115 VAL   X CB  1 
ATOM   889  C  CG1 . VAL   A 1 129 ? 18.459  -2.876  -1.774  1.00 34.70  ? 115 VAL   X CG1 1 
ATOM   890  C  CG2 . VAL   A 1 129 ? 19.527  -2.090  -3.929  1.00 37.47  ? 115 VAL   X CG2 1 
ATOM   891  N  N   . ALA   A 1 130 ? 16.548  0.074   -0.755  1.00 35.85  ? 116 ALA   X N   1 
ATOM   892  C  CA  . ALA   A 1 130 ? 16.021  0.360   0.593   1.00 35.13  ? 116 ALA   X CA  1 
ATOM   893  C  C   . ALA   A 1 130 ? 15.820  -0.963  1.311   1.00 37.54  ? 116 ALA   X C   1 
ATOM   894  O  O   . ALA   A 1 130 ? 14.876  -1.709  0.925   1.00 38.23  ? 116 ALA   X O   1 
ATOM   895  C  CB  . ALA   A 1 130 ? 14.743  1.132   0.467   1.00 37.30  ? 116 ALA   X CB  1 
ATOM   896  N  N   . SER   A 1 131 ? 16.699  -1.305  2.249   1.00 34.13  ? 117 SER   X N   1 
ATOM   897  C  CA  . SER   A 1 131 ? 16.608  -2.583  3.004   1.00 37.35  ? 117 SER   X CA  1 
ATOM   898  C  C   . SER   A 1 131 ? 15.161  -2.724  3.528   1.00 34.11  ? 117 SER   X C   1 
ATOM   899  O  O   . SER   A 1 131 ? 14.635  -3.804  3.572   1.00 33.53  ? 117 SER   X O   1 
ATOM   900  C  CB  . SER   A 1 131 ? 17.694  -2.646  4.100   1.00 36.15  ? 117 SER   X CB  1 
ATOM   901  O  OG  . SER   A 1 131 ? 17.494  -1.710  5.162   1.00 36.18  ? 117 SER   X OG  1 
ATOM   902  N  N   . HIS   A 1 132 ? 14.608  -1.610  3.989   1.00 32.82  ? 118 HIS   X N   1 
ATOM   903  C  CA  . HIS   A 1 132 ? 13.262  -1.392  4.544   1.00 33.14  ? 118 HIS   X CA  1 
ATOM   904  C  C   . HIS   A 1 132 ? 13.065  0.122   4.722   1.00 33.52  ? 118 HIS   X C   1 
ATOM   905  O  O   . HIS   A 1 132 ? 13.956  0.881   4.314   1.00 32.92  ? 118 HIS   X O   1 
ATOM   906  C  CB  . HIS   A 1 132 ? 13.002  -2.234  5.797   1.00 31.56  ? 118 HIS   X CB  1 
ATOM   907  C  CG  . HIS   A 1 132 ? 13.835  -1.901  6.963   1.00 30.79  ? 118 HIS   X CG  1 
ATOM   908  N  ND1 . HIS   A 1 132 ? 15.233  -1.894  6.932   1.00 31.89  ? 118 HIS   X ND1 1 
ATOM   909  C  CD2 . HIS   A 1 132 ? 13.471  -1.640  8.236   1.00 31.81  ? 118 HIS   X CD2 1 
ATOM   910  C  CE1 . HIS   A 1 132 ? 15.675  -1.595  8.153   1.00 36.59  ? 118 HIS   X CE1 1 
ATOM   911  N  NE2 . HIS   A 1 132 ? 14.619  -1.446  8.955   1.00 32.26  ? 118 HIS   X NE2 1 
ATOM   912  N  N   . LEU   A 1 133 ? 11.900  0.554   5.204   1.00 33.03  ? 119 LEU   X N   1 
ATOM   913  C  CA  . LEU   A 1 133 ? 11.538  2.000   5.152   1.00 31.28  ? 119 LEU   X CA  1 
ATOM   914  C  C   . LEU   A 1 133 ? 11.477  2.621   6.547   1.00 29.89  ? 119 LEU   X C   1 
ATOM   915  O  O   . LEU   A 1 133 ? 10.834  3.670   6.687   1.00 30.71  ? 119 LEU   X O   1 
ATOM   916  C  CB  . LEU   A 1 133 ? 10.213  2.080   4.392   1.00 32.04  ? 119 LEU   X CB  1 
ATOM   917  C  CG  . LEU   A 1 133 ? 10.329  1.787   2.901   1.00 28.93  ? 119 LEU   X CG  1 
ATOM   918  C  CD1 . LEU   A 1 133 ? 8.985   1.926   2.202   1.00 33.57  ? 119 LEU   X CD1 1 
ATOM   919  C  CD2 . LEU   A 1 133 ? 11.378  2.657   2.250   1.00 32.12  ? 119 LEU   X CD2 1 
ATOM   920  N  N   . HIS   A 1 134 ? 12.127  2.026   7.548   1.00 30.06  ? 120 HIS   X N   1 
ATOM   921  C  CA  . HIS   A 1 134 ? 12.295  2.623   8.888   1.00 32.13  ? 120 HIS   X CA  1 
ATOM   922  C  C   . HIS   A 1 134 ? 13.061  3.959   8.793   1.00 33.41  ? 120 HIS   X C   1 
ATOM   923  O  O   . HIS   A 1 134 ? 13.812  4.146   7.848   1.00 31.24  ? 120 HIS   X O   1 
ATOM   924  C  CB  . HIS   A 1 134 ? 13.005  1.681   9.850   1.00 31.90  ? 120 HIS   X CB  1 
ATOM   925  C  CG  . HIS   A 1 134 ? 12.144  0.676   10.500  1.00 32.42  ? 120 HIS   X CG  1 
ATOM   926  N  ND1 . HIS   A 1 134 ? 12.656  -0.506  10.976  1.00 36.01  ? 120 HIS   X ND1 1 
ATOM   927  C  CD2 . HIS   A 1 134 ? 10.794  0.595   10.614  1.00 35.60  ? 120 HIS   X CD2 1 
ATOM   928  C  CE1 . HIS   A 1 134 ? 11.632  -1.230  11.475  1.00 35.55  ? 120 HIS   X CE1 1 
ATOM   929  N  NE2 . HIS   A 1 134 ? 10.497  -0.548  11.282  1.00 34.01  ? 120 HIS   X NE2 1 
ATOM   930  N  N   . LEU   A 1 135 ? 12.862  4.817   9.804   1.00 32.89  ? 121 LEU   X N   1 
ATOM   931  C  CA  . LEU   A 1 135 ? 13.396  6.195   9.922   1.00 37.02  ? 121 LEU   X CA  1 
ATOM   932  C  C   . LEU   A 1 135 ? 14.916  6.252   9.718   1.00 35.35  ? 121 LEU   X C   1 
ATOM   933  O  O   . LEU   A 1 135 ? 15.360  7.284   9.203   1.00 35.49  ? 121 LEU   X O   1 
ATOM   934  C  CB  . LEU   A 1 135 ? 12.946  6.792   11.263  1.00 36.55  ? 121 LEU   X CB  1 
ATOM   935  C  CG  . LEU   A 1 135 ? 13.600  6.312   12.545  1.00 38.90  ? 121 LEU   X CG  1 
ATOM   936  C  CD1 . LEU   A 1 135 ? 12.993  7.064   13.736  1.00 39.39  ? 121 LEU   X CD1 1 
ATOM   937  C  CD2 . LEU   A 1 135 ? 13.464  4.814   12.754  1.00 40.64  ? 121 LEU   X CD2 1 
ATOM   938  N  N   . ASP   A 1 136 ? 15.662  5.194   10.079  1.00 37.25  ? 122 ASP   X N   1 
ATOM   939  C  CA  . ASP   A 1 136 ? 17.151  5.181   10.131  1.00 36.49  ? 122 ASP   X CA  1 
ATOM   940  C  C   . ASP   A 1 136 ? 17.710  4.575   8.849   1.00 38.52  ? 122 ASP   X C   1 
ATOM   941  O  O   . ASP   A 1 136 ? 18.927  4.415   8.794   1.00 40.80  ? 122 ASP   X O   1 
ATOM   942  C  CB  . ASP   A 1 136 ? 17.662  4.472   11.391  1.00 38.54  ? 122 ASP   X CB  1 
ATOM   943  C  CG  . ASP   A 1 136 ? 17.125  3.063   11.584  1.00 40.07  ? 122 ASP   X CG  1 
ATOM   944  O  OD1 . ASP   A 1 136 ? 15.884  2.847   11.399  1.00 33.66  ? 122 ASP   X OD1 1 
ATOM   945  O  OD2 . ASP   A 1 136 ? 17.920  2.214   11.945  1.00 41.54  ? 122 ASP   X OD2 1 
ATOM   946  N  N   . HIS   A 1 137 ? 16.871  4.267   7.852   1.00 33.46  ? 123 HIS   X N   1 
ATOM   947  C  CA  . HIS   A 1 137 ? 17.293  3.611   6.589   1.00 33.76  ? 123 HIS   X CA  1 
ATOM   948  C  C   . HIS   A 1 137 ? 16.745  4.339   5.370   1.00 31.63  ? 123 HIS   X C   1 
ATOM   949  O  O   . HIS   A 1 137 ? 17.406  4.277   4.315   1.00 33.44  ? 123 HIS   X O   1 
ATOM   950  C  CB  . HIS   A 1 137 ? 16.935  2.114   6.577   1.00 34.57  ? 123 HIS   X CB  1 
ATOM   951  C  CG  . HIS   A 1 137 ? 17.556  1.350   7.688   1.00 34.70  ? 123 HIS   X CG  1 
ATOM   952  N  ND1 . HIS   A 1 137 ? 18.741  0.666   7.516   1.00 36.37  ? 123 HIS   X ND1 1 
ATOM   953  C  CD2 . HIS   A 1 137 ? 17.189  1.200   8.995   1.00 37.93  ? 123 HIS   X CD2 1 
ATOM   954  C  CE1 . HIS   A 1 137 ? 19.074  0.100   8.643   1.00 35.75  ? 123 HIS   X CE1 1 
ATOM   955  N  NE2 . HIS   A 1 137 ? 18.156  0.434   9.602   1.00 34.06  ? 123 HIS   X NE2 1 
ATOM   956  N  N   . ALA   A 1 138 ? 15.569  4.960   5.468   1.00 36.24  ? 124 ALA   X N   1 
ATOM   957  C  CA  . ALA   A 1 138 ? 14.871  5.559   4.303   1.00 36.31  ? 124 ALA   X CA  1 
ATOM   958  C  C   . ALA   A 1 138 ? 14.841  7.092   4.420   1.00 36.04  ? 124 ALA   X C   1 
ATOM   959  O  O   . ALA   A 1 138 ? 14.181  7.697   3.587   1.00 34.34  ? 124 ALA   X O   1 
ATOM   960  C  CB  . ALA   A 1 138 ? 13.450  5.004   4.213   1.00 35.54  ? 124 ALA   X CB  1 
ATOM   961  N  N   . GLY   A 1 139 ? 15.521  7.678   5.403   1.00 35.92  ? 125 GLY   X N   1 
ATOM   962  C  CA  . GLY   A 1 139 ? 15.514  9.129   5.685   1.00 37.63  ? 125 GLY   X CA  1 
ATOM   963  C  C   . GLY   A 1 139 ? 15.910  10.041  4.518   1.00 38.84  ? 125 GLY   X C   1 
ATOM   964  O  O   . GLY   A 1 139 ? 15.325  11.150  4.421   1.00 43.67  ? 125 GLY   X O   1 
ATOM   965  N  N   . CYS   A 1 140 ? 16.811  9.632   3.616   1.00 36.72  ? 126 CYS   X N   1 
ATOM   966  C  CA  . CYS   A 1 140 ? 17.213  10.514  2.480   1.00 38.67  ? 126 CYS   X CA  1 
ATOM   967  C  C   . CYS   A 1 140 ? 16.818  9.942   1.133   1.00 38.31  ? 126 CYS   X C   1 
ATOM   968  O  O   . CYS   A 1 140 ? 17.376  10.408  0.106   1.00 37.53  ? 126 CYS   X O   1 
ATOM   969  C  CB  . CYS   A 1 140 ? 18.710  10.852  2.489   1.00 41.56  ? 126 CYS   X CB  1 
ATOM   970  S  SG  . CYS   A 1 140 ? 19.278  11.527  4.069   1.00 41.46  ? 126 CYS   X SG  1 
ATOM   971  N  N   . LEU   A 1 141 ? 15.847  9.026   1.050   1.00 36.33  ? 127 LEU   X N   1 
ATOM   972  C  CA  . LEU   A 1 141 ? 15.411  8.579   -0.303  1.00 33.00  ? 127 LEU   X CA  1 
ATOM   973  C  C   . LEU   A 1 141 ? 15.039  9.782   -1.171  1.00 29.78  ? 127 LEU   X C   1 
ATOM   974  O  O   . LEU   A 1 141 ? 15.207  9.699   -2.394  1.00 33.39  ? 127 LEU   X O   1 
ATOM   975  C  CB  . LEU   A 1 141 ? 14.184  7.641   -0.233  1.00 33.63  ? 127 LEU   X CB  1 
ATOM   976  C  CG  . LEU   A 1 141 ? 14.439  6.252   0.335   1.00 36.42  ? 127 LEU   X CG  1 
ATOM   977  C  CD1 . LEU   A 1 141 ? 13.101  5.533   0.520   1.00 41.38  ? 127 LEU   X CD1 1 
ATOM   978  C  CD2 . LEU   A 1 141 ? 15.360  5.455   -0.577  1.00 37.56  ? 127 LEU   X CD2 1 
ATOM   979  N  N   . GLU   A 1 142 ? 14.424  10.808  -0.604  1.00 36.42  ? 128 GLU   X N   1 
ATOM   980  C  CA  . GLU   A 1 142 ? 13.889  11.964  -1.398  1.00 39.11  ? 128 GLU   X CA  1 
ATOM   981  C  C   . GLU   A 1 142 ? 14.977  12.659  -2.240  1.00 38.09  ? 128 GLU   X C   1 
ATOM   982  O  O   . GLU   A 1 142 ? 14.630  13.279  -3.236  1.00 38.63  ? 128 GLU   X O   1 
ATOM   983  C  CB  . GLU   A 1 142 ? 13.223  12.998  -0.483  1.00 43.70  ? 128 GLU   X CB  1 
ATOM   984  C  CG  . GLU   A 1 142 ? 14.175  13.685  0.468   1.00 41.18  ? 128 GLU   X CG  1 
ATOM   985  C  CD  . GLU   A 1 142 ? 13.411  14.370  1.583   1.00 44.21  ? 128 GLU   X CD  1 
ATOM   986  O  OE1 . GLU   A 1 142 ? 13.297  15.592  1.566   1.00 46.44  ? 128 GLU   X OE1 1 
ATOM   987  O  OE2 . GLU   A 1 142 ? 12.929  13.682  2.473   1.00 47.44  ? 128 GLU   X OE2 1 
ATOM   988  N  N   . MET   A 1 143 ? 16.248  12.534  -1.888  1.00 40.31  ? 129 MET   X N   1 
ATOM   989  C  CA  . MET   A 1 143 ? 17.373  13.104  -2.694  1.00 41.83  ? 129 MET   X CA  1 
ATOM   990  C  C   . MET   A 1 143 ? 17.480  12.436  -4.063  1.00 40.91  ? 129 MET   X C   1 
ATOM   991  O  O   . MET   A 1 143 ? 17.997  13.061  -5.026  1.00 39.38  ? 129 MET   X O   1 
ATOM   992  C  CB  . MET   A 1 143 ? 18.709  12.884  -1.973  1.00 46.95  ? 129 MET   X CB  1 
ATOM   993  C  CG  . MET   A 1 143 ? 18.959  13.830  -0.810  1.00 54.87  ? 129 MET   X CG  1 
ATOM   994  S  SD  . MET   A 1 143 ? 20.407  13.288  0.160   1.00 58.40  ? 129 MET   X SD  1 
ATOM   995  C  CE  . MET   A 1 143 ? 21.606  12.973  -1.128  1.00 58.75  ? 129 MET   X CE  1 
ATOM   996  N  N   . PHE   A 1 144 ? 17.081  11.173  -4.192  1.00 38.48  ? 130 PHE   X N   1 
ATOM   997  C  CA  . PHE   A 1 144 ? 17.520  10.344  -5.341  1.00 39.10  ? 130 PHE   X CA  1 
ATOM   998  C  C   . PHE   A 1 144 ? 16.427  10.300  -6.409  1.00 44.61  ? 130 PHE   X C   1 
ATOM   999  O  O   . PHE   A 1 144 ? 15.924  9.202   -6.757  1.00 41.87  ? 130 PHE   X O   1 
ATOM   1000 C  CB  . PHE   A 1 144 ? 18.043  9.005   -4.850  1.00 37.72  ? 130 PHE   X CB  1 
ATOM   1001 C  CG  . PHE   A 1 144 ? 19.125  9.147   -3.828  1.00 42.48  ? 130 PHE   X CG  1 
ATOM   1002 C  CD1 . PHE   A 1 144 ? 20.391  9.586   -4.203  1.00 40.83  ? 130 PHE   X CD1 1 
ATOM   1003 C  CD2 . PHE   A 1 144 ? 18.876  8.887   -2.497  1.00 36.59  ? 130 PHE   X CD2 1 
ATOM   1004 C  CE1 . PHE   A 1 144 ? 21.379  9.750   -3.259  1.00 37.49  ? 130 PHE   X CE1 1 
ATOM   1005 C  CE2 . PHE   A 1 144 ? 19.873  9.078   -1.554  1.00 42.04  ? 130 PHE   X CE2 1 
ATOM   1006 C  CZ  . PHE   A 1 144 ? 21.117  9.516   -1.938  1.00 39.34  ? 130 PHE   X CZ  1 
ATOM   1007 N  N   . THR   A 1 145 ? 16.202  11.453  -7.041  1.00 39.17  ? 131 THR   X N   1 
ATOM   1008 C  CA  . THR   A 1 145 ? 15.174  11.684  -8.087  1.00 42.32  ? 131 THR   X CA  1 
ATOM   1009 C  C   . THR   A 1 145 ? 15.621  11.134  -9.436  1.00 44.21  ? 131 THR   X C   1 
ATOM   1010 O  O   . THR   A 1 145 ? 14.788  11.085  -10.342 1.00 41.74  ? 131 THR   X O   1 
ATOM   1011 C  CB  . THR   A 1 145 ? 14.841  13.178  -8.165  1.00 42.74  ? 131 THR   X CB  1 
ATOM   1012 O  OG1 . THR   A 1 145 ? 16.092  13.849  -8.312  1.00 43.61  ? 131 THR   X OG1 1 
ATOM   1013 C  CG2 . THR   A 1 145 ? 14.176  13.694  -6.918  1.00 42.64  ? 131 THR   X CG2 1 
ATOM   1014 N  N   . ASN   A 1 146 ? 16.860  10.684  -9.591  1.00 41.79  ? 132 ASN   X N   1 
ATOM   1015 C  CA  . ASN   A 1 146 ? 17.340  10.171  -10.895 1.00 45.00  ? 132 ASN   X CA  1 
ATOM   1016 C  C   . ASN   A 1 146 ? 17.543  8.652   -10.823 1.00 43.65  ? 132 ASN   X C   1 
ATOM   1017 O  O   . ASN   A 1 146 ? 17.931  8.056   -11.829 1.00 45.77  ? 132 ASN   X O   1 
ATOM   1018 C  CB  . ASN   A 1 146 ? 18.581  10.957  -11.334 1.00 51.72  ? 132 ASN   X CB  1 
ATOM   1019 C  CG  . ASN   A 1 146 ? 18.842  10.902  -12.819 1.00 54.64  ? 132 ASN   X CG  1 
ATOM   1020 O  OD1 . ASN   A 1 146 ? 20.001  10.970  -13.228 1.00 65.49  ? 132 ASN   X OD1 1 
ATOM   1021 N  ND2 . ASN   A 1 146 ? 17.808  10.750  -13.633 1.00 55.31  ? 132 ASN   X ND2 1 
ATOM   1022 N  N   . ALA   A 1 147 ? 17.260  8.047   -9.672  1.00 40.27  ? 133 ALA   X N   1 
ATOM   1023 C  CA  . ALA   A 1 147 ? 17.476  6.609   -9.414  1.00 40.10  ? 133 ALA   X CA  1 
ATOM   1024 C  C   . ALA   A 1 147 ? 16.163  5.837   -9.610  1.00 39.74  ? 133 ALA   X C   1 
ATOM   1025 O  O   . ALA   A 1 147 ? 15.052  6.441   -9.560  1.00 36.28  ? 133 ALA   X O   1 
ATOM   1026 C  CB  . ALA   A 1 147 ? 18.022  6.442   -8.011  1.00 40.51  ? 133 ALA   X CB  1 
ATOM   1027 N  N   . THR   A 1 148 ? 16.301  4.521   -9.796  1.00 38.10  ? 134 THR   X N   1 
ATOM   1028 C  CA  . THR   A 1 148 ? 15.254  3.519   -9.470  1.00 38.91  ? 134 THR   X CA  1 
ATOM   1029 C  C   . THR   A 1 148 ? 15.400  3.104   -8.000  1.00 36.61  ? 134 THR   X C   1 
ATOM   1030 O  O   . THR   A 1 148 ? 16.510  2.701   -7.628  1.00 33.92  ? 134 THR   X O   1 
ATOM   1031 C  CB  . THR   A 1 148 ? 15.358  2.307   -10.381 1.00 40.30  ? 134 THR   X CB  1 
ATOM   1032 O  OG1 . THR   A 1 148 ? 15.271  2.844   -11.696 1.00 39.82  ? 134 THR   X OG1 1 
ATOM   1033 C  CG2 . THR   A 1 148 ? 14.274  1.291   -10.081 1.00 45.84  ? 134 THR   X CG2 1 
ATOM   1034 N  N   . ILE   A 1 149 ? 14.345  3.271   -7.198  1.00 32.36  ? 135 ILE   X N   1 
ATOM   1035 C  CA  . ILE   A 1 149 ? 14.315  2.930   -5.763  1.00 33.79  ? 135 ILE   X CA  1 
ATOM   1036 C  C   . ILE   A 1 149 ? 13.744  1.513   -5.663  1.00 36.22  ? 135 ILE   X C   1 
ATOM   1037 O  O   . ILE   A 1 149 ? 12.562  1.315   -5.983  1.00 35.49  ? 135 ILE   X O   1 
ATOM   1038 C  CB  . ILE   A 1 149 ? 13.478  3.905   -4.921  1.00 35.15  ? 135 ILE   X CB  1 
ATOM   1039 C  CG1 . ILE   A 1 149 ? 13.799  5.372   -5.216  1.00 38.35  ? 135 ILE   X CG1 1 
ATOM   1040 C  CG2 . ILE   A 1 149 ? 13.645  3.545   -3.461  1.00 39.10  ? 135 ILE   X CG2 1 
ATOM   1041 C  CD1 . ILE   A 1 149 ? 15.223  5.808   -4.891  1.00 38.01  ? 135 ILE   X CD1 1 
ATOM   1042 N  N   . ILE   A 1 150 ? 14.592  0.578   -5.282  1.00 34.23  ? 136 ILE   X N   1 
ATOM   1043 C  CA  . ILE   A 1 150 ? 14.238  -0.848  -5.075  1.00 35.09  ? 136 ILE   X CA  1 
ATOM   1044 C  C   . ILE   A 1 150 ? 13.825  -1.050  -3.615  1.00 34.25  ? 136 ILE   X C   1 
ATOM   1045 O  O   . ILE   A 1 150 ? 14.569  -0.707  -2.676  1.00 34.01  ? 136 ILE   X O   1 
ATOM   1046 C  CB  . ILE   A 1 150 ? 15.375  -1.760  -5.549  1.00 34.78  ? 136 ILE   X CB  1 
ATOM   1047 C  CG1 . ILE   A 1 150 ? 15.743  -1.466  -7.013  1.00 36.12  ? 136 ILE   X CG1 1 
ATOM   1048 C  CG2 . ILE   A 1 150 ? 14.979  -3.211  -5.346  1.00 32.97  ? 136 ILE   X CG2 1 
ATOM   1049 C  CD1 . ILE   A 1 150 ? 17.052  -2.004  -7.408  1.00 41.63  ? 136 ILE   X CD1 1 
ATOM   1050 N  N   . VAL   A 1 151 ? 12.620  -1.575  -3.431  1.00 30.32  ? 137 VAL   X N   1 
ATOM   1051 C  CA  . VAL   A 1 151 ? 12.013  -1.725  -2.089  1.00 30.53  ? 137 VAL   X CA  1 
ATOM   1052 C  C   . VAL   A 1 151 ? 11.143  -2.981  -2.134  1.00 30.49  ? 137 VAL   X C   1 
ATOM   1053 O  O   . VAL   A 1 151 ? 10.617  -3.287  -3.206  1.00 30.28  ? 137 VAL   X O   1 
ATOM   1054 C  CB  . VAL   A 1 151 ? 11.199  -0.480  -1.689  1.00 32.52  ? 137 VAL   X CB  1 
ATOM   1055 C  CG1 . VAL   A 1 151 ? 9.970   -0.284  -2.556  1.00 38.03  ? 137 VAL   X CG1 1 
ATOM   1056 C  CG2 . VAL   A 1 151 ? 10.835  -0.512  -0.223  1.00 34.21  ? 137 VAL   X CG2 1 
ATOM   1057 N  N   . HIS   A 1 152 ? 10.975  -3.671  -1.004  1.00 30.97  ? 138 HIS   X N   1 
ATOM   1058 C  CA  . HIS   A 1 152 ? 10.021  -4.799  -0.907  1.00 28.55  ? 138 HIS   X CA  1 
ATOM   1059 C  C   . HIS   A 1 152 ? 8.574   -4.282  -1.035  1.00 32.54  ? 138 HIS   X C   1 
ATOM   1060 O  O   . HIS   A 1 152 ? 8.189   -3.324  -0.338  1.00 29.05  ? 138 HIS   X O   1 
ATOM   1061 C  CB  . HIS   A 1 152 ? 10.217  -5.554  0.392   1.00 30.96  ? 138 HIS   X CB  1 
ATOM   1062 C  CG  . HIS   A 1 152 ? 9.660   -6.934  0.327   1.00 31.21  ? 138 HIS   X CG  1 
ATOM   1063 N  ND1 . HIS   A 1 152 ? 8.296   -7.161  0.365   1.00 31.41  ? 138 HIS   X ND1 1 
ATOM   1064 C  CD2 . HIS   A 1 152 ? 10.261  -8.138  0.198   1.00 34.19  ? 138 HIS   X CD2 1 
ATOM   1065 C  CE1 . HIS   A 1 152 ? 8.066   -8.465  0.258   1.00 34.86  ? 138 HIS   X CE1 1 
ATOM   1066 N  NE2 . HIS   A 1 152 ? 9.260   -9.103  0.169   1.00 33.09  ? 138 HIS   X NE2 1 
ATOM   1067 N  N   . GLU   A 1 153 ? 7.767   -4.917  -1.873  1.00 30.65  ? 139 GLU   X N   1 
ATOM   1068 C  CA  . GLU   A 1 153 ? 6.369   -4.475  -2.108  1.00 33.10  ? 139 GLU   X CA  1 
ATOM   1069 C  C   . GLU   A 1 153 ? 5.598   -4.420  -0.778  1.00 31.43  ? 139 GLU   X C   1 
ATOM   1070 O  O   . GLU   A 1 153 ? 4.833   -3.476  -0.611  1.00 30.31  ? 139 GLU   X O   1 
ATOM   1071 C  CB  . GLU   A 1 153 ? 5.663   -5.311  -3.171  1.00 37.13  ? 139 GLU   X CB  1 
ATOM   1072 C  CG  . GLU   A 1 153 ? 5.137   -6.639  -2.715  1.00 43.05  ? 139 GLU   X CG  1 
ATOM   1073 C  CD  . GLU   A 1 153 ? 4.348   -7.372  -3.813  1.00 52.57  ? 139 GLU   X CD  1 
ATOM   1074 O  OE1 . GLU   A 1 153 ? 3.848   -6.641  -4.697  1.00 50.84  ? 139 GLU   X OE1 1 
ATOM   1075 O  OE2 . GLU   A 1 153 ? 4.261   -8.683  -3.793  1.00 42.12  ? 139 GLU   X OE2 1 
ATOM   1076 N  N   . ASP   A 1 154 ? 5.838   -5.338  0.157   1.00 28.31  ? 140 ASP   X N   1 
ATOM   1077 C  CA  . ASP   A 1 154 ? 5.034   -5.398  1.411   1.00 31.41  ? 140 ASP   X CA  1 
ATOM   1078 C  C   . ASP   A 1 154 ? 5.504   -4.266  2.330   1.00 30.05  ? 140 ASP   X C   1 
ATOM   1079 O  O   . ASP   A 1 154 ? 4.683   -3.695  3.077   1.00 29.68  ? 140 ASP   X O   1 
ATOM   1080 C  CB  . ASP   A 1 154 ? 5.123   -6.773  2.077   1.00 29.87  ? 140 ASP   X CB  1 
ATOM   1081 C  CG  . ASP   A 1 154 ? 4.444   -7.870  1.297   1.00 31.76  ? 140 ASP   X CG  1 
ATOM   1082 O  OD1 . ASP   A 1 154 ? 3.350   -7.600  0.802   1.00 33.83  ? 140 ASP   X OD1 1 
ATOM   1083 O  OD2 . ASP   A 1 154 ? 5.011   -9.016  1.210   1.00 32.28  ? 140 ASP   X OD2 1 
ATOM   1084 N  N   . GLU   A 1 155 ? 6.774   -3.869  2.218   1.00 32.44  ? 141 GLU   X N   1 
ATOM   1085 C  CA  . GLU   A 1 155 ? 7.301   -2.745  3.030   1.00 27.79  ? 141 GLU   X CA  1 
ATOM   1086 C  C   . GLU   A 1 155 ? 6.699   -1.434  2.529   1.00 30.63  ? 141 GLU   X C   1 
ATOM   1087 O  O   . GLU   A 1 155 ? 6.261   -0.601  3.357   1.00 30.56  ? 141 GLU   X O   1 
ATOM   1088 C  CB  . GLU   A 1 155 ? 8.822   -2.782  3.011   1.00 29.97  ? 141 GLU   X CB  1 
ATOM   1089 C  CG  . GLU   A 1 155 ? 9.430   -1.766  3.949   1.00 28.95  ? 141 GLU   X CG  1 
ATOM   1090 C  CD  . GLU   A 1 155 ? 9.335   -2.090  5.420   1.00 33.73  ? 141 GLU   X CD  1 
ATOM   1091 O  OE1 . GLU   A 1 155 ? 8.796   -3.156  5.760   1.00 30.18  ? 141 GLU   X OE1 1 
ATOM   1092 O  OE2 . GLU   A 1 155 ? 9.825   -1.275  6.239   1.00 33.47  ? 141 GLU   X OE2 1 
ATOM   1093 N  N   . PHE   A 1 156 ? 6.690   -1.255  1.222   1.00 30.52  ? 142 PHE   X N   1 
ATOM   1094 C  CA  . PHE   A 1 156 ? 6.116   -0.054  0.563   1.00 31.90  ? 142 PHE   X CA  1 
ATOM   1095 C  C   . PHE   A 1 156 ? 4.643   0.076   0.947   1.00 34.57  ? 142 PHE   X C   1 
ATOM   1096 O  O   . PHE   A 1 156 ? 4.239   1.147   1.393   1.00 32.07  ? 142 PHE   X O   1 
ATOM   1097 C  CB  . PHE   A 1 156 ? 6.366   -0.171  -0.940  1.00 33.19  ? 142 PHE   X CB  1 
ATOM   1098 C  CG  . PHE   A 1 156 ? 6.154   1.060   -1.783  1.00 31.29  ? 142 PHE   X CG  1 
ATOM   1099 C  CD1 . PHE   A 1 156 ? 6.680   2.279   -1.401  1.00 34.84  ? 142 PHE   X CD1 1 
ATOM   1100 C  CD2 . PHE   A 1 156 ? 5.523   0.987   -3.004  1.00 31.81  ? 142 PHE   X CD2 1 
ATOM   1101 C  CE1 . PHE   A 1 156 ? 6.508   3.406   -2.188  1.00 36.26  ? 142 PHE   X CE1 1 
ATOM   1102 C  CE2 . PHE   A 1 156 ? 5.351   2.116   -3.790  1.00 32.29  ? 142 PHE   X CE2 1 
ATOM   1103 C  CZ  . PHE   A 1 156 ? 5.888   3.310   -3.398  1.00 34.56  ? 142 PHE   X CZ  1 
ATOM   1104 N  N   . ASN   A 1 157 ? 3.863   -1.015  0.813   1.00 29.76  ? 143 ASN   X N   1 
ATOM   1105 C  CA  . ASN   A 1 157 ? 2.422   -1.023  1.144   1.00 30.13  ? 143 ASN   X CA  1 
ATOM   1106 C  C   . ASN   A 1 157 ? 2.240   -0.562  2.581   1.00 32.23  ? 143 ASN   X C   1 
ATOM   1107 O  O   . ASN   A 1 157 ? 1.339   0.290   2.824   1.00 32.35  ? 143 ASN   X O   1 
ATOM   1108 C  CB  . ASN   A 1 157 ? 1.776   -2.384  0.845   1.00 33.64  ? 143 ASN   X CB  1 
ATOM   1109 C  CG  . ASN   A 1 157 ? 1.696   -2.649  -0.641  1.00 33.27  ? 143 ASN   X CG  1 
ATOM   1110 O  OD1 . ASN   A 1 157 ? 1.838   -1.751  -1.464  1.00 35.47  ? 143 ASN   X OD1 1 
ATOM   1111 N  ND2 . ASN   A 1 157 ? 1.426   -3.875  -1.019  1.00 36.92  ? 143 ASN   X ND2 1 
ATOM   1112 N  N   . GLY   A 1 158 ? 2.981   -1.156  3.518   1.00 30.82  ? 144 GLY   X N   1 
ATOM   1113 C  CA  . GLY   A 1 158 ? 2.840   -0.872  4.954   1.00 31.27  ? 144 GLY   X CA  1 
ATOM   1114 C  C   . GLY   A 1 158 ? 3.144   0.600   5.232   1.00 31.61  ? 144 GLY   X C   1 
ATOM   1115 O  O   . GLY   A 1 158 ? 2.398   1.263   5.995   1.00 33.11  ? 144 GLY   X O   1 
ATOM   1116 N  N   . ALA   A 1 159 ? 4.200   1.124   4.649   1.00 32.69  ? 145 ALA   X N   1 
ATOM   1117 C  CA  . ALA   A 1 159 ? 4.612   2.532   4.881   1.00 32.64  ? 145 ALA   X CA  1 
ATOM   1118 C  C   . ALA   A 1 159 ? 3.526   3.441   4.290   1.00 31.77  ? 145 ALA   X C   1 
ATOM   1119 O  O   . ALA   A 1 159 ? 3.127   4.423   4.915   1.00 33.52  ? 145 ALA   X O   1 
ATOM   1120 C  CB  . ALA   A 1 159 ? 5.989   2.807   4.300   1.00 32.65  ? 145 ALA   X CB  1 
ATOM   1121 N  N   . LEU   A 1 160 ? 3.061   3.132   3.107   1.00 30.18  ? 146 LEU   X N   1 
ATOM   1122 C  CA  . LEU   A 1 160 ? 2.031   3.980   2.465   1.00 32.79  ? 146 LEU   X CA  1 
ATOM   1123 C  C   . LEU   A 1 160 ? 0.723   3.955   3.281   1.00 36.29  ? 146 LEU   X C   1 
ATOM   1124 O  O   . LEU   A 1 160 ? 0.069   5.027   3.343   1.00 33.35  ? 146 LEU   X O   1 
ATOM   1125 C  CB  . LEU   A 1 160 ? 1.815   3.549   1.018   1.00 31.09  ? 146 LEU   X CB  1 
ATOM   1126 C  CG  . LEU   A 1 160 ? 2.942   3.773   0.026   1.00 31.70  ? 146 LEU   X CG  1 
ATOM   1127 C  CD1 . LEU   A 1 160 ? 2.536   3.202   -1.322  1.00 32.74  ? 146 LEU   X CD1 1 
ATOM   1128 C  CD2 . LEU   A 1 160 ? 3.303   5.242   -0.116  1.00 35.24  ? 146 LEU   X CD2 1 
ATOM   1129 N  N   . GLN   A 1 161 ? 0.337   2.834   3.917   1.00 33.28  ? 147 GLN   X N   1 
ATOM   1130 C  CA  . GLN   A 1 161 ? -0.824  2.833   4.844   1.00 33.77  ? 147 GLN   X CA  1 
ATOM   1131 C  C   . GLN   A 1 161 ? -0.544  3.739   6.059   1.00 34.76  ? 147 GLN   X C   1 
ATOM   1132 O  O   . GLN   A 1 161 ? -1.474  4.400   6.525   1.00 34.22  ? 147 GLN   X O   1 
ATOM   1133 C  CB  . GLN   A 1 161 ? -1.207  1.441   5.340   1.00 33.12  ? 147 GLN   X CB  1 
ATOM   1134 C  CG  . GLN   A 1 161 ? -1.884  0.567   4.285   1.00 35.68  ? 147 GLN   X CG  1 
ATOM   1135 C  CD  . GLN   A 1 161 ? -2.679  -0.550  4.925   1.00 36.46  ? 147 GLN   X CD  1 
ATOM   1136 O  OE1 . GLN   A 1 161 ? -3.207  -0.382  6.017   1.00 36.16  ? 147 GLN   X OE1 1 
ATOM   1137 N  NE2 . GLN   A 1 161 ? -2.758  -1.694  4.262   1.00 35.02  ? 147 GLN   X NE2 1 
ATOM   1138 N  N   . CYS   A 1 162 ? 0.661   3.746   6.615   1.00 32.45  ? 148 CYS   X N   1 
ATOM   1139 C  CA  . CYS   A 1 162 ? 0.997   4.644   7.757   1.00 36.71  ? 148 CYS   X CA  1 
ATOM   1140 C  C   . CYS   A 1 162 ? 0.731   6.090   7.318   1.00 34.52  ? 148 CYS   X C   1 
ATOM   1141 O  O   . CYS   A 1 162 ? 0.141   6.822   8.088   1.00 38.89  ? 148 CYS   X O   1 
ATOM   1142 C  CB  . CYS   A 1 162 ? 2.440   4.504   8.186   1.00 36.31  ? 148 CYS   X CB  1 
ATOM   1143 S  SG  . CYS   A 1 162 ? 2.801   2.944   9.029   1.00 40.06  ? 148 CYS   X SG  1 
ATOM   1144 N  N   . TYR   A 1 163 ? 1.127   6.427   6.095   1.00 35.49  ? 149 TYR   X N   1 
ATOM   1145 C  CA  . TYR   A 1 163 ? 0.973   7.772   5.495   1.00 36.83  ? 149 TYR   X CA  1 
ATOM   1146 C  C   . TYR   A 1 163 ? -0.511  8.107   5.363   1.00 34.91  ? 149 TYR   X C   1 
ATOM   1147 O  O   . TYR   A 1 163 ? -0.953  9.202   5.800   1.00 37.00  ? 149 TYR   X O   1 
ATOM   1148 C  CB  . TYR   A 1 163 ? 1.612   7.847   4.116   1.00 36.14  ? 149 TYR   X CB  1 
ATOM   1149 C  CG  . TYR   A 1 163 ? 1.543   9.215   3.481   1.00 35.84  ? 149 TYR   X CG  1 
ATOM   1150 C  CD1 . TYR   A 1 163 ? 2.307   10.260  3.961   1.00 40.16  ? 149 TYR   X CD1 1 
ATOM   1151 C  CD2 . TYR   A 1 163 ? 0.699   9.469   2.416   1.00 37.06  ? 149 TYR   X CD2 1 
ATOM   1152 C  CE1 . TYR   A 1 163 ? 2.223   11.531  3.410   1.00 40.75  ? 149 TYR   X CE1 1 
ATOM   1153 C  CE2 . TYR   A 1 163 ? 0.606   10.727  1.842   1.00 41.75  ? 149 TYR   X CE2 1 
ATOM   1154 C  CZ  . TYR   A 1 163 ? 1.383   11.760  2.341   1.00 41.41  ? 149 TYR   X CZ  1 
ATOM   1155 O  OH  . TYR   A 1 163 ? 1.330   12.997  1.778   1.00 43.02  ? 149 TYR   X OH  1 
ATOM   1156 N  N   . ALA   A 1 164 ? -1.250  7.204   4.720   1.00 34.21  ? 150 ALA   X N   1 
ATOM   1157 C  CA  . ALA   A 1 164 ? -2.688  7.378   4.410   1.00 37.63  ? 150 ALA   X CA  1 
ATOM   1158 C  C   . ALA   A 1 164 ? -3.513  7.491   5.690   1.00 39.10  ? 150 ALA   X C   1 
ATOM   1159 O  O   . ALA   A 1 164 ? -4.477  8.235   5.631   1.00 37.39  ? 150 ALA   X O   1 
ATOM   1160 C  CB  . ALA   A 1 164 ? -3.213  6.268   3.534   1.00 36.96  ? 150 ALA   X CB  1 
ATOM   1161 N  N   . ARG   A 1 165 ? -3.147  6.800   6.773   1.00 32.15  ? 151 ARG   X N   1 
ATOM   1162 C  CA  . ARG   A 1 165 ? -3.870  6.807   8.076   1.00 39.23  ? 151 ARG   X CA  1 
ATOM   1163 C  C   . ARG   A 1 165 ? -3.383  7.982   8.935   1.00 39.14  ? 151 ARG   X C   1 
ATOM   1164 O  O   . ARG   A 1 165 ? -3.737  8.027   10.108  1.00 41.72  ? 151 ARG   X O   1 
ATOM   1165 C  CB  . ARG   A 1 165 ? -3.622  5.500   8.844   1.00 39.76  ? 151 ARG   X CB  1 
ATOM   1166 C  CG  . ARG   A 1 165 ? -4.165  4.256   8.155   1.00 41.48  ? 151 ARG   X CG  1 
ATOM   1167 C  CD  . ARG   A 1 165 ? -3.685  2.965   8.809   1.00 44.20  ? 151 ARG   X CD  1 
ATOM   1168 N  NE  . ARG   A 1 165 ? -4.135  1.739   8.116   1.00 47.37  ? 151 ARG   X NE  1 
ATOM   1169 C  CZ  . ARG   A 1 165 ? -5.291  1.129   8.366   1.00 47.64  ? 151 ARG   X CZ  1 
ATOM   1170 N  NH1 . ARG   A 1 165 ? -6.116  1.646   9.246   1.00 49.99  ? 151 ARG   X NH1 1 
ATOM   1171 N  NH2 . ARG   A 1 165 ? -5.632  0.013   7.751   1.00 44.06  ? 151 ARG   X NH2 1 
ATOM   1172 N  N   . ASN   A 1 166 ? -2.487  8.814   8.398   1.00 39.28  ? 152 ASN   X N   1 
ATOM   1173 C  CA  . ASN   A 1 166 ? -1.933  9.994   9.107   1.00 43.11  ? 152 ASN   X CA  1 
ATOM   1174 C  C   . ASN   A 1 166 ? -1.271  9.579   10.429  1.00 45.08  ? 152 ASN   X C   1 
ATOM   1175 O  O   . ASN   A 1 166 ? -1.429  10.309  11.409  1.00 45.03  ? 152 ASN   X O   1 
ATOM   1176 C  CB  . ASN   A 1 166 ? -3.008  11.077  9.293   1.00 44.22  ? 152 ASN   X CB  1 
ATOM   1177 C  CG  . ASN   A 1 166 ? -3.306  11.781  7.986   1.00 45.43  ? 152 ASN   X CG  1 
ATOM   1178 O  OD1 . ASN   A 1 166 ? -2.473  12.507  7.424   1.00 42.08  ? 152 ASN   X OD1 1 
ATOM   1179 N  ND2 . ASN   A 1 166 ? -4.483  11.531  7.441   1.00 45.26  ? 152 ASN   X ND2 1 
ATOM   1180 N  N   . GLN   A 1 167 ? -0.504  8.488   10.469  1.00 44.12  ? 153 GLN   X N   1 
ATOM   1181 C  CA  . GLN   A 1 167 ? 0.233   8.109   11.707  1.00 45.12  ? 153 GLN   X CA  1 
ATOM   1182 C  C   . GLN   A 1 167 ? 1.474   9.014   11.856  1.00 43.85  ? 153 GLN   X C   1 
ATOM   1183 O  O   . GLN   A 1 167 ? 2.324   9.038   10.964  1.00 41.69  ? 153 GLN   X O   1 
ATOM   1184 C  CB  . GLN   A 1 167 ? 0.601   6.628   11.710  1.00 49.00  ? 153 GLN   X CB  1 
ATOM   1185 C  CG  . GLN   A 1 167 ? -0.645  5.773   11.896  1.00 74.11  ? 153 GLN   X CG  1 
ATOM   1186 C  CD  . GLN   A 1 167 ? -0.365  4.347   12.305  1.00 85.77  ? 153 GLN   X CD  1 
ATOM   1187 O  OE1 . GLN   A 1 167 ? -0.113  4.063   13.479  1.00 97.47  ? 153 GLN   X OE1 1 
ATOM   1188 N  NE2 . GLN   A 1 167 ? -0.445  3.442   11.337  1.00 63.00  ? 153 GLN   X NE2 1 
ATOM   1189 N  N   . LYS   A 1 168 ? 1.620   9.667   12.996  1.00 48.47  ? 154 LYS   X N   1 
ATOM   1190 C  CA  . LYS   A 1 168 ? 2.705   10.649  13.288  1.00 53.02  ? 154 LYS   X CA  1 
ATOM   1191 C  C   . LYS   A 1 168 ? 3.804   10.045  14.155  1.00 51.09  ? 154 LYS   X C   1 
ATOM   1192 O  O   . LYS   A 1 168 ? 4.909   10.575  14.121  1.00 56.12  ? 154 LYS   X O   1 
ATOM   1193 C  CB  . LYS   A 1 168 ? 2.103   11.858  14.008  1.00 62.03  ? 154 LYS   X CB  1 
ATOM   1194 C  CG  . LYS   A 1 168 ? 1.285   12.770  13.101  1.00 67.53  ? 154 LYS   X CG  1 
ATOM   1195 C  CD  . LYS   A 1 168 ? 1.950   12.965  11.752  1.00 67.70  ? 154 LYS   X CD  1 
ATOM   1196 C  CE  . LYS   A 1 168 ? 1.536   14.214  11.020  1.00 72.32  ? 154 LYS   X CE  1 
ATOM   1197 N  NZ  . LYS   A 1 168 ? 0.480   13.921  10.021  1.00 79.43  ? 154 LYS   X NZ  1 
ATOM   1198 N  N   . GLU   A 1 169 ? 3.491   9.012   14.928  1.00 49.92  ? 155 GLU   X N   1 
ATOM   1199 C  CA  . GLU   A 1 169 ? 4.437   8.350   15.858  1.00 57.14  ? 155 GLU   X CA  1 
ATOM   1200 C  C   . GLU   A 1 169 ? 4.952   7.080   15.180  1.00 53.53  ? 155 GLU   X C   1 
ATOM   1201 O  O   . GLU   A 1 169 ? 4.439   6.755   14.102  1.00 54.45  ? 155 GLU   X O   1 
ATOM   1202 C  CB  . GLU   A 1 169 ? 3.721   8.043   17.167  1.00 61.96  ? 155 GLU   X CB  1 
ATOM   1203 C  CG  . GLU   A 1 169 ? 2.879   9.215   17.628  1.00 72.14  ? 155 GLU   X CG  1 
ATOM   1204 C  CD  . GLU   A 1 169 ? 3.011   9.536   19.096  1.00 77.55  ? 155 GLU   X CD  1 
ATOM   1205 O  OE1 . GLU   A 1 169 ? 2.079   9.191   19.848  1.00 93.41  ? 155 GLU   X OE1 1 
ATOM   1206 O  OE2 . GLU   A 1 169 ? 4.034   10.128  19.473  1.00 74.28  ? 155 GLU   X OE2 1 
ATOM   1207 N  N   . GLY   A 1 170 ? 5.928   6.421   15.790  1.00 47.90  ? 156 GLY   X N   1 
ATOM   1208 C  CA  . GLY   A 1 170 ? 6.479   5.148   15.308  1.00 51.51  ? 156 GLY   X CA  1 
ATOM   1209 C  C   . GLY   A 1 170 ? 7.592   5.349   14.294  1.00 51.89  ? 156 GLY   X C   1 
ATOM   1210 O  O   . GLY   A 1 170 ? 8.091   6.484   14.110  1.00 43.05  ? 156 GLY   X O   1 
ATOM   1211 N  N   . ALA   A 1 171 ? 8.012   4.247   13.678  1.00 45.24  ? 157 ALA   X N   1 
ATOM   1212 C  CA  . ALA   A 1 171 ? 9.297   4.160   12.965  1.00 45.26  ? 157 ALA   X CA  1 
ATOM   1213 C  C   . ALA   A 1 171 ? 9.151   4.563   11.492  1.00 39.57  ? 157 ALA   X C   1 
ATOM   1214 O  O   . ALA   A 1 171 ? 10.203  4.559   10.792  1.00 41.84  ? 157 ALA   X O   1 
ATOM   1215 C  CB  . ALA   A 1 171 ? 9.818   2.755   13.152  1.00 43.98  ? 157 ALA   X CB  1 
ATOM   1216 N  N   . TYR   A 1 172 ? 7.927   4.864   11.017  1.00 35.24  ? 158 TYR   X N   1 
ATOM   1217 C  CA  . TYR   A 1 172 ? 7.642   5.240   9.615   1.00 34.41  ? 158 TYR   X CA  1 
ATOM   1218 C  C   . TYR   A 1 172 ? 7.318   6.736   9.594   1.00 37.71  ? 158 TYR   X C   1 
ATOM   1219 O  O   . TYR   A 1 172 ? 6.311   7.093   10.177  1.00 37.33  ? 158 TYR   X O   1 
ATOM   1220 C  CB  . TYR   A 1 172 ? 6.542   4.353   9.000   1.00 35.47  ? 158 TYR   X CB  1 
ATOM   1221 C  CG  . TYR   A 1 172 ? 7.009   2.926   8.830   1.00 33.89  ? 158 TYR   X CG  1 
ATOM   1222 C  CD1 . TYR   A 1 172 ? 7.841   2.569   7.780   1.00 31.05  ? 158 TYR   X CD1 1 
ATOM   1223 C  CD2 . TYR   A 1 172 ? 6.756   1.983   9.809   1.00 36.22  ? 158 TYR   X CD2 1 
ATOM   1224 C  CE1 . TYR   A 1 172 ? 8.371   1.292   7.683   1.00 33.85  ? 158 TYR   X CE1 1 
ATOM   1225 C  CE2 . TYR   A 1 172 ? 7.282   0.700   9.726   1.00 37.21  ? 158 TYR   X CE2 1 
ATOM   1226 C  CZ  . TYR   A 1 172 ? 8.060   0.334   8.632   1.00 34.72  ? 158 TYR   X CZ  1 
ATOM   1227 O  OH  . TYR   A 1 172 ? 8.586   -0.938  8.558   1.00 35.20  ? 158 TYR   X OH  1 
ATOM   1228 N  N   . ILE   A 1 173 ? 8.192   7.572   9.038   1.00 35.85  ? 159 ILE   X N   1 
ATOM   1229 C  CA  . ILE   A 1 173 ? 8.121   9.054   9.280   1.00 34.87  ? 159 ILE   X CA  1 
ATOM   1230 C  C   . ILE   A 1 173 ? 7.235   9.708   8.229   1.00 32.52  ? 159 ILE   X C   1 
ATOM   1231 O  O   . ILE   A 1 173 ? 7.584   9.684   7.014   1.00 32.79  ? 159 ILE   X O   1 
ATOM   1232 C  CB  . ILE   A 1 173 ? 9.525   9.703   9.283   1.00 34.08  ? 159 ILE   X CB  1 
ATOM   1233 C  CG1 . ILE   A 1 173 ? 10.469  9.065   10.300  1.00 36.38  ? 159 ILE   X CG1 1 
ATOM   1234 C  CG2 . ILE   A 1 173 ? 9.381   11.203  9.501   1.00 37.34  ? 159 ILE   X CG2 1 
ATOM   1235 C  CD1 . ILE   A 1 173 ? 9.934   9.035   11.736  1.00 40.72  ? 159 ILE   X CD1 1 
ATOM   1236 N  N   . TRP   A 1 174 ? 6.096   10.236  8.657   1.00 32.84  ? 160 TRP   X N   1 
ATOM   1237 C  CA  . TRP   A 1 174 ? 5.060   10.796  7.747   1.00 37.78  ? 160 TRP   X CA  1 
ATOM   1238 C  C   . TRP   A 1 174 ? 5.714   11.793  6.769   1.00 36.05  ? 160 TRP   X C   1 
ATOM   1239 O  O   . TRP   A 1 174 ? 5.436   11.758  5.522   1.00 34.11  ? 160 TRP   X O   1 
ATOM   1240 C  CB  . TRP   A 1 174 ? 3.948   11.448  8.592   1.00 40.04  ? 160 TRP   X CB  1 
ATOM   1241 C  CG  . TRP   A 1 174 ? 2.714   11.698  7.790   1.00 37.48  ? 160 TRP   X CG  1 
ATOM   1242 C  CD1 . TRP   A 1 174 ? 1.689   10.816  7.617   1.00 43.07  ? 160 TRP   X CD1 1 
ATOM   1243 C  CD2 . TRP   A 1 174 ? 2.385   12.867  7.012   1.00 39.90  ? 160 TRP   X CD2 1 
ATOM   1244 N  NE1 . TRP   A 1 174 ? 0.754   11.351  6.782   1.00 39.32  ? 160 TRP   X NE1 1 
ATOM   1245 C  CE2 . TRP   A 1 174 ? 1.142   12.606  6.396   1.00 43.45  ? 160 TRP   X CE2 1 
ATOM   1246 C  CE3 . TRP   A 1 174 ? 3.036   14.075  6.726   1.00 39.99  ? 160 TRP   X CE3 1 
ATOM   1247 C  CZ2 . TRP   A 1 174 ? 0.521   13.522  5.543   1.00 43.67  ? 160 TRP   X CZ2 1 
ATOM   1248 C  CZ3 . TRP   A 1 174 ? 2.427   14.983  5.888   1.00 43.87  ? 160 TRP   X CZ3 1 
ATOM   1249 C  CH2 . TRP   A 1 174 ? 1.177   14.714  5.314   1.00 44.75  ? 160 TRP   X CH2 1 
ATOM   1250 N  N   . ALA   A 1 175 ? 6.548   12.702  7.306   1.00 37.26  ? 161 ALA   X N   1 
ATOM   1251 C  CA  . ALA   A 1 175 ? 7.109   13.828  6.534   1.00 39.57  ? 161 ALA   X CA  1 
ATOM   1252 C  C   . ALA   A 1 175 ? 8.153   13.277  5.547   1.00 38.06  ? 161 ALA   X C   1 
ATOM   1253 O  O   . ALA   A 1 175 ? 8.263   13.834  4.432   1.00 37.24  ? 161 ALA   X O   1 
ATOM   1254 C  CB  . ALA   A 1 175 ? 7.639   14.909  7.471   1.00 41.23  ? 161 ALA   X CB  1 
ATOM   1255 N  N   . ASP   A 1 176 ? 8.809   12.141  5.855   1.00 33.85  ? 162 ASP   X N   1 
ATOM   1256 C  CA  . ASP   A 1 176 ? 9.743   11.518  4.879   1.00 33.97  ? 162 ASP   X CA  1 
ATOM   1257 C  C   . ASP   A 1 176 ? 8.911   10.952  3.717   1.00 35.00  ? 162 ASP   X C   1 
ATOM   1258 O  O   . ASP   A 1 176 ? 9.257   11.179  2.531   1.00 34.50  ? 162 ASP   X O   1 
ATOM   1259 C  CB  . ASP   A 1 176 ? 10.652  10.461  5.524   1.00 35.07  ? 162 ASP   X CB  1 
ATOM   1260 C  CG  . ASP   A 1 176 ? 11.737  10.976  6.486   1.00 39.44  ? 162 ASP   X CG  1 
ATOM   1261 O  OD1 . ASP   A 1 176 ? 11.882  12.216  6.613   1.00 41.20  ? 162 ASP   X OD1 1 
ATOM   1262 O  OD2 . ASP   A 1 176 ? 12.459  10.108  7.130   1.00 38.25  ? 162 ASP   X OD2 1 
ATOM   1263 N  N   . ILE   A 1 177 ? 7.812   10.254  4.039   1.00 37.71  ? 163 ILE   X N   1 
ATOM   1264 C  CA  . ILE   A 1 177 ? 6.964   9.600   3.005   1.00 36.78  ? 163 ILE   X CA  1 
ATOM   1265 C  C   . ILE   A 1 177 ? 6.364   10.718  2.152   1.00 33.71  ? 163 ILE   X C   1 
ATOM   1266 O  O   . ILE   A 1 177 ? 6.402   10.592  0.910   1.00 34.71  ? 163 ILE   X O   1 
ATOM   1267 C  CB  . ILE   A 1 177 ? 5.899   8.680   3.634   1.00 34.49  ? 163 ILE   X CB  1 
ATOM   1268 C  CG1 . ILE   A 1 177 ? 6.525   7.579   4.494   1.00 34.66  ? 163 ILE   X CG1 1 
ATOM   1269 C  CG2 . ILE   A 1 177 ? 5.040   8.066   2.527   1.00 34.10  ? 163 ILE   X CG2 1 
ATOM   1270 C  CD1 . ILE   A 1 177 ? 5.572   6.947   5.470   1.00 35.48  ? 163 ILE   X CD1 1 
ATOM   1271 N  N   . ASP   A 1 178 ? 5.885   11.788  2.807   1.00 36.42  ? 164 ASP   X N   1 
ATOM   1272 C  CA  . ASP   A 1 178 ? 5.370   13.013  2.121   1.00 35.92  ? 164 ASP   X CA  1 
ATOM   1273 C  C   . ASP   A 1 178 ? 6.391   13.484  1.077   1.00 36.36  ? 164 ASP   X C   1 
ATOM   1274 O  O   . ASP   A 1 178 ? 6.007   13.687  -0.106  1.00 36.54  ? 164 ASP   X O   1 
ATOM   1275 C  CB  . ASP   A 1 178 ? 4.987   14.113  3.121   1.00 40.27  ? 164 ASP   X CB  1 
ATOM   1276 C  CG  . ASP   A 1 178 ? 4.065   15.189  2.538   1.00 51.74  ? 164 ASP   X CG  1 
ATOM   1277 O  OD1 . ASP   A 1 178 ? 3.037   14.846  1.961   1.00 45.57  ? 164 ASP   X OD1 1 
ATOM   1278 O  OD2 . ASP   A 1 178 ? 4.429   16.359  2.590   1.00 49.66  ? 164 ASP   X OD2 1 
ATOM   1279 N  N   . ALA   A 1 179 ? 7.666   13.603  1.433   1.00 39.51  ? 165 ALA   X N   1 
ATOM   1280 C  CA  . ALA   A 1 179 ? 8.699   14.089  0.481   1.00 37.77  ? 165 ALA   X CA  1 
ATOM   1281 C  C   . ALA   A 1 179 ? 8.966   13.046  -0.629  1.00 37.39  ? 165 ALA   X C   1 
ATOM   1282 O  O   . ALA   A 1 179 ? 9.218   13.433  -1.831  1.00 36.98  ? 165 ALA   X O   1 
ATOM   1283 C  CB  . ALA   A 1 179 ? 9.934   14.449  1.267   1.00 38.96  ? 165 ALA   X CB  1 
ATOM   1284 N  N   . TRP   A 1 180 ? 8.873   11.745  -0.337  1.00 36.42  ? 166 TRP   X N   1 
ATOM   1285 C  CA  . TRP   A 1 180 ? 9.073   10.727  -1.417  1.00 39.13  ? 166 TRP   X CA  1 
ATOM   1286 C  C   . TRP   A 1 180 ? 8.075   10.935  -2.538  1.00 36.22  ? 166 TRP   X C   1 
ATOM   1287 O  O   . TRP   A 1 180 ? 8.463   10.765  -3.703  1.00 41.54  ? 166 TRP   X O   1 
ATOM   1288 C  CB  . TRP   A 1 180 ? 8.992   9.280   -0.929  1.00 38.54  ? 166 TRP   X CB  1 
ATOM   1289 C  CG  . TRP   A 1 180 ? 9.846   8.987   0.255   1.00 36.13  ? 166 TRP   X CG  1 
ATOM   1290 C  CD1 . TRP   A 1 180 ? 10.932  9.698   0.686   1.00 40.52  ? 166 TRP   X CD1 1 
ATOM   1291 C  CD2 . TRP   A 1 180 ? 9.691   7.882   1.161   1.00 39.34  ? 166 TRP   X CD2 1 
ATOM   1292 N  NE1 . TRP   A 1 180 ? 11.428  9.140   1.830   1.00 37.43  ? 166 TRP   X NE1 1 
ATOM   1293 C  CE2 . TRP   A 1 180 ? 10.707  8.013   2.135   1.00 39.75  ? 166 TRP   X CE2 1 
ATOM   1294 C  CE3 . TRP   A 1 180 ? 8.789   6.809   1.246   1.00 38.71  ? 166 TRP   X CE3 1 
ATOM   1295 C  CZ2 . TRP   A 1 180 ? 10.826  7.130   3.211   1.00 37.61  ? 166 TRP   X CZ2 1 
ATOM   1296 C  CZ3 . TRP   A 1 180 ? 8.931   5.924   2.293   1.00 37.73  ? 166 TRP   X CZ3 1 
ATOM   1297 C  CH2 . TRP   A 1 180 ? 9.907   6.096   3.266   1.00 38.27  ? 166 TRP   X CH2 1 
ATOM   1298 N  N   . ILE   A 1 181 ? 6.828   11.232  -2.179  1.00 36.34  ? 167 ILE   X N   1 
ATOM   1299 C  CA  . ILE   A 1 181 ? 5.703   11.383  -3.143  1.00 40.52  ? 167 ILE   X CA  1 
ATOM   1300 C  C   . ILE   A 1 181 ? 5.829   12.753  -3.842  1.00 41.37  ? 167 ILE   X C   1 
ATOM   1301 O  O   . ILE   A 1 181 ? 5.772   12.804  -5.062  1.00 41.55  ? 167 ILE   X O   1 
ATOM   1302 C  CB  . ILE   A 1 181 ? 4.363   11.247  -2.388  1.00 39.90  ? 167 ILE   X CB  1 
ATOM   1303 C  CG1 . ILE   A 1 181 ? 4.247   9.896   -1.682  1.00 38.66  ? 167 ILE   X CG1 1 
ATOM   1304 C  CG2 . ILE   A 1 181 ? 3.183   11.535  -3.312  1.00 38.70  ? 167 ILE   X CG2 1 
ATOM   1305 C  CD1 . ILE   A 1 181 ? 3.035   9.770   -0.806  1.00 42.52  ? 167 ILE   X CD1 1 
ATOM   1306 N  N   . LYS   A 1 182 ? 6.038   13.831  -3.099  1.00 42.42  ? 168 LYS   X N   1 
ATOM   1307 C  CA  . LYS   A 1 182 ? 6.229   15.171  -3.737  1.00 45.59  ? 168 LYS   X CA  1 
ATOM   1308 C  C   . LYS   A 1 182 ? 7.417   15.174  -4.711  1.00 44.60  ? 168 LYS   X C   1 
ATOM   1309 O  O   . LYS   A 1 182 ? 7.329   15.867  -5.758  1.00 42.66  ? 168 LYS   X O   1 
ATOM   1310 C  CB  . LYS   A 1 182 ? 6.334   16.236  -2.652  1.00 51.70  ? 168 LYS   X CB  1 
ATOM   1311 C  CG  . LYS   A 1 182 ? 4.982   16.614  -2.063  1.00 58.97  ? 168 LYS   X CG  1 
ATOM   1312 C  CD  . LYS   A 1 182 ? 5.105   17.508  -0.860  1.00 67.35  ? 168 LYS   X CD  1 
ATOM   1313 C  CE  . LYS   A 1 182 ? 3.762   17.798  -0.221  1.00 70.40  ? 168 LYS   X CE  1 
ATOM   1314 N  NZ  . LYS   A 1 182 ? 3.946   18.436  1.101   1.00 78.34  ? 168 LYS   X NZ  1 
ATOM   1315 N  N   . ASN   A 1 183 ? 8.474   14.401  -4.434  1.00 42.05  ? 169 ASN   X N   1 
ATOM   1316 C  CA  . ASN   A 1 183 ? 9.715   14.407  -5.249  1.00 40.32  ? 169 ASN   X CA  1 
ATOM   1317 C  C   . ASN   A 1 183 ? 9.585   13.434  -6.398  1.00 40.09  ? 169 ASN   X C   1 
ATOM   1318 O  O   . ASN   A 1 183 ? 10.521  13.334  -7.168  1.00 37.85  ? 169 ASN   X O   1 
ATOM   1319 C  CB  . ASN   A 1 183 ? 10.964  14.143  -4.404  1.00 46.11  ? 169 ASN   X CB  1 
ATOM   1320 C  CG  . ASN   A 1 183 ? 11.342  15.334  -3.534  1.00 49.92  ? 169 ASN   X CG  1 
ATOM   1321 O  OD1 . ASN   A 1 183 ? 10.606  16.278  -3.404  1.00 54.94  ? 169 ASN   X OD1 1 
ATOM   1322 N  ND2 . ASN   A 1 183 ? 12.470  15.279  -2.875  1.00 61.77  ? 169 ASN   X ND2 1 
ATOM   1323 N  N   . ASN   A 1 184 ? 8.488   12.686  -6.493  1.00 40.51  ? 170 ASN   X N   1 
ATOM   1324 C  CA  . ASN   A 1 184 ? 8.219   11.849  -7.673  1.00 37.59  ? 170 ASN   X CA  1 
ATOM   1325 C  C   . ASN   A 1 184 ? 9.322   10.788  -7.847  1.00 36.76  ? 170 ASN   X C   1 
ATOM   1326 O  O   . ASN   A 1 184 ? 9.823   10.586  -8.965  1.00 38.84  ? 170 ASN   X O   1 
ATOM   1327 C  CB  . ASN   A 1 184 ? 8.062   12.711  -8.930  1.00 43.92  ? 170 ASN   X CB  1 
ATOM   1328 C  CG  . ASN   A 1 184 ? 7.293   11.936  -9.969  1.00 52.04  ? 170 ASN   X CG  1 
ATOM   1329 O  OD1 . ASN   A 1 184 ? 6.414   11.141  -9.622  1.00 53.71  ? 170 ASN   X OD1 1 
ATOM   1330 N  ND2 . ASN   A 1 184 ? 7.668   12.090  -11.220 1.00 55.61  ? 170 ASN   X ND2 1 
ATOM   1331 N  N   . LEU   A 1 185 ? 9.678   10.094  -6.777  1.00 38.06  ? 171 LEU   X N   1 
ATOM   1332 C  CA  . LEU   A 1 185 ? 10.638  8.972   -6.858  1.00 36.93  ? 171 LEU   X CA  1 
ATOM   1333 C  C   . LEU   A 1 185 ? 10.084  7.901   -7.783  1.00 41.32  ? 171 LEU   X C   1 
ATOM   1334 O  O   . LEU   A 1 185 ? 8.866   7.767   -7.888  1.00 37.85  ? 171 LEU   X O   1 
ATOM   1335 C  CB  . LEU   A 1 185 ? 10.932  8.417   -5.465  1.00 37.79  ? 171 LEU   X CB  1 
ATOM   1336 C  CG  . LEU   A 1 185 ? 11.554  9.452   -4.521  1.00 38.53  ? 171 LEU   X CG  1 
ATOM   1337 C  CD1 . LEU   A 1 185 ? 11.960  8.853   -3.184  1.00 35.84  ? 171 LEU   X CD1 1 
ATOM   1338 C  CD2 . LEU   A 1 185 ? 12.761  10.107  -5.186  1.00 39.44  ? 171 LEU   X CD2 1 
ATOM   1339 N  N   . GLN   A 1 186 ? 10.997  7.197   -8.434  1.00 38.87  ? 172 GLN   X N   1 
ATOM   1340 C  CA  . GLN   A 1 186 ? 10.706  6.075   -9.359  1.00 39.59  ? 172 GLN   X CA  1 
ATOM   1341 C  C   . GLN   A 1 186 ? 10.935  4.742   -8.610  1.00 44.82  ? 172 GLN   X C   1 
ATOM   1342 O  O   . GLN   A 1 186 ? 12.077  4.425   -8.276  1.00 40.66  ? 172 GLN   X O   1 
ATOM   1343 C  CB  . GLN   A 1 186 ? 11.596  6.210   -10.594 1.00 39.94  ? 172 GLN   X CB  1 
ATOM   1344 C  CG  . GLN   A 1 186 ? 11.366  7.522   -11.358 1.00 45.27  ? 172 GLN   X CG  1 
ATOM   1345 C  CD  . GLN   A 1 186 ? 9.914   7.685   -11.774 1.00 43.87  ? 172 GLN   X CD  1 
ATOM   1346 O  OE1 . GLN   A 1 186 ? 9.362   6.886   -12.523 1.00 49.82  ? 172 GLN   X OE1 1 
ATOM   1347 N  NE2 . GLN   A 1 186 ? 9.249   8.667   -11.208 1.00 46.67  ? 172 GLN   X NE2 1 
ATOM   1348 N  N   . TRP   A 1 187 ? 9.866   4.003   -8.340  1.00 37.33  ? 173 TRP   X N   1 
ATOM   1349 C  CA  . TRP   A 1 187 ? 9.908   2.771   -7.523  1.00 39.12  ? 173 TRP   X CA  1 
ATOM   1350 C  C   . TRP   A 1 187 ? 9.913   1.529   -8.407  1.00 36.07  ? 173 TRP   X C   1 
ATOM   1351 O  O   . TRP   A 1 187 ? 9.207   1.483   -9.381  1.00 36.49  ? 173 TRP   X O   1 
ATOM   1352 C  CB  . TRP   A 1 187 ? 8.724   2.764   -6.561  1.00 36.76  ? 173 TRP   X CB  1 
ATOM   1353 C  CG  . TRP   A 1 187 ? 8.634   3.961   -5.673  1.00 35.02  ? 173 TRP   X CG  1 
ATOM   1354 C  CD1 . TRP   A 1 187 ? 7.975   5.134   -5.900  1.00 38.04  ? 173 TRP   X CD1 1 
ATOM   1355 C  CD2 . TRP   A 1 187 ? 9.196   4.069   -4.360  1.00 35.10  ? 173 TRP   X CD2 1 
ATOM   1356 N  NE1 . TRP   A 1 187 ? 8.097   5.950   -4.814  1.00 36.12  ? 173 TRP   X NE1 1 
ATOM   1357 C  CE2 . TRP   A 1 187 ? 8.812   5.328   -3.843  1.00 36.75  ? 173 TRP   X CE2 1 
ATOM   1358 C  CE3 . TRP   A 1 187 ? 9.948   3.206   -3.565  1.00 35.42  ? 173 TRP   X CE3 1 
ATOM   1359 C  CZ2 . TRP   A 1 187 ? 9.194   5.768   -2.585  1.00 35.27  ? 173 TRP   X CZ2 1 
ATOM   1360 C  CZ3 . TRP   A 1 187 ? 10.310  3.628   -2.305  1.00 36.70  ? 173 TRP   X CZ3 1 
ATOM   1361 C  CH2 . TRP   A 1 187 ? 9.907   4.881   -1.821  1.00 37.08  ? 173 TRP   X CH2 1 
ATOM   1362 N  N   . ARG   A 1 188 ? 10.724  0.552   -8.044  1.00 36.18  ? 174 ARG   X N   1 
ATOM   1363 C  CA  . ARG   A 1 188 ? 10.596  -0.846  -8.488  1.00 35.13  ? 174 ARG   X CA  1 
ATOM   1364 C  C   . ARG   A 1 188 ? 10.343  -1.683  -7.226  1.00 34.54  ? 174 ARG   X C   1 
ATOM   1365 O  O   . ARG   A 1 188 ? 11.250  -1.773  -6.378  1.00 34.05  ? 174 ARG   X O   1 
ATOM   1366 C  CB  . ARG   A 1 188 ? 11.837  -1.335  -9.246  1.00 40.73  ? 174 ARG   X CB  1 
ATOM   1367 C  CG  . ARG   A 1 188 ? 11.640  -2.721  -9.866  1.00 45.96  ? 174 ARG   X CG  1 
ATOM   1368 C  CD  . ARG   A 1 188 ? 12.673  -3.722  -9.415  1.00 60.85  ? 174 ARG   X CD  1 
ATOM   1369 N  NE  . ARG   A 1 188 ? 12.737  -4.963  -10.171 1.00 55.14  ? 174 ARG   X NE  1 
ATOM   1370 C  CZ  . ARG   A 1 188 ? 12.009  -6.055  -9.959  1.00 58.46  ? 174 ARG   X CZ  1 
ATOM   1371 N  NH1 . ARG   A 1 188 ? 11.051  -6.120  -9.037  1.00 51.32  ? 174 ARG   X NH1 1 
ATOM   1372 N  NH2 . ARG   A 1 188 ? 12.251  -7.108  -10.717 1.00 55.98  ? 174 ARG   X NH2 1 
ATOM   1373 N  N   . THR   A 1 189 ? 9.153   -2.259  -7.071  1.00 32.60  ? 175 THR   X N   1 
ATOM   1374 C  CA  . THR   A 1 189 ? 8.852   -3.087  -5.883  1.00 33.26  ? 175 THR   X CA  1 
ATOM   1375 C  C   . THR   A 1 189 ? 9.316   -4.515  -6.148  1.00 33.03  ? 175 THR   X C   1 
ATOM   1376 O  O   . THR   A 1 189 ? 9.134   -5.033  -7.267  1.00 34.86  ? 175 THR   X O   1 
ATOM   1377 C  CB  . THR   A 1 189 ? 7.387   -2.990  -5.487  1.00 34.46  ? 175 THR   X CB  1 
ATOM   1378 O  OG1 . THR   A 1 189 ? 6.639   -3.432  -6.609  1.00 36.65  ? 175 THR   X OG1 1 
ATOM   1379 C  CG2 . THR   A 1 189 ? 6.964   -1.607  -5.069  1.00 39.57  ? 175 THR   X CG2 1 
ATOM   1380 N  N   . VAL   A 1 190 ? 9.968   -5.099  -5.160  1.00 32.14  ? 176 VAL   X N   1 
ATOM   1381 C  CA  . VAL   A 1 190 ? 10.277  -6.547  -5.158  1.00 31.73  ? 176 VAL   X CA  1 
ATOM   1382 C  C   . VAL   A 1 190 ? 9.015   -7.295  -4.676  1.00 30.70  ? 176 VAL   X C   1 
ATOM   1383 O  O   . VAL   A 1 190 ? 8.523   -7.058  -3.565  1.00 31.23  ? 176 VAL   X O   1 
ATOM   1384 C  CB  . VAL   A 1 190 ? 11.547  -6.824  -4.327  1.00 33.58  ? 176 VAL   X CB  1 
ATOM   1385 C  CG1 . VAL   A 1 190 ? 11.886  -8.307  -4.347  1.00 32.78  ? 176 VAL   X CG1 1 
ATOM   1386 C  CG2 . VAL   A 1 190 ? 12.731  -5.992  -4.850  1.00 35.12  ? 176 VAL   X CG2 1 
ATOM   1387 N  N   . LYS   A 1 191 ? 8.498   -8.183  -5.513  1.00 31.78  ? 177 LYS   X N   1 
ATOM   1388 C  CA  . LYS   A 1 191 ? 7.248   -8.916  -5.215  1.00 31.17  ? 177 LYS   X CA  1 
ATOM   1389 C  C   . LYS   A 1 191 ? 7.539   -9.978  -4.168  1.00 33.98  ? 177 LYS   X C   1 
ATOM   1390 O  O   . LYS   A 1 191 ? 8.691   -10.482 -4.050  1.00 33.33  ? 177 LYS   X O   1 
ATOM   1391 C  CB  . LYS   A 1 191 ? 6.667   -9.577  -6.474  1.00 34.73  ? 177 LYS   X CB  1 
ATOM   1392 C  CG  . LYS   A 1 191 ? 6.360   -8.630  -7.642  1.00 46.55  ? 177 LYS   X CG  1 
ATOM   1393 C  CD  . LYS   A 1 191 ? 5.513   -7.398  -7.304  1.00 54.62  ? 177 LYS   X CD  1 
ATOM   1394 C  CE  . LYS   A 1 191 ? 5.325   -6.406  -8.459  1.00 51.85  ? 177 LYS   X CE  1 
ATOM   1395 N  NZ  . LYS   A 1 191 ? 6.513   -5.547  -8.722  1.00 48.33  ? 177 LYS   X NZ  1 
ATOM   1396 N  N   . ARG   A 1 192 ? 6.515   -10.301 -3.408  1.00 35.06  ? 178 ARG   X N   1 
ATOM   1397 C  CA  . ARG   A 1 192 ? 6.614   -11.247 -2.289  1.00 34.09  ? 178 ARG   X CA  1 
ATOM   1398 C  C   . ARG   A 1 192 ? 7.299   -12.546 -2.726  1.00 41.31  ? 178 ARG   X C   1 
ATOM   1399 O  O   . ARG   A 1 192 ? 8.128   -13.034 -1.973  1.00 43.83  ? 178 ARG   X O   1 
ATOM   1400 C  CB  . ARG   A 1 192 ? 5.226   -11.468 -1.676  1.00 33.56  ? 178 ARG   X CB  1 
ATOM   1401 C  CG  . ARG   A 1 192 ? 5.276   -12.253 -0.380  1.00 38.18  ? 178 ARG   X CG  1 
ATOM   1402 C  CD  . ARG   A 1 192 ? 3.896   -12.478 0.164   1.00 38.07  ? 178 ARG   X CD  1 
ATOM   1403 N  NE  . ARG   A 1 192 ? 3.329   -11.240 0.678   1.00 33.35  ? 178 ARG   X NE  1 
ATOM   1404 C  CZ  . ARG   A 1 192 ? 2.100   -11.138 1.106   1.00 35.69  ? 178 ARG   X CZ  1 
ATOM   1405 N  NH1 . ARG   A 1 192 ? 1.328   -12.211 1.113   1.00 33.41  ? 178 ARG   X NH1 1 
ATOM   1406 N  NH2 . ARG   A 1 192 ? 1.631   -9.969  1.534   1.00 34.42  ? 178 ARG   X NH2 1 
ATOM   1407 N  N   . HIS   A 1 193 ? 7.023   -13.131 -3.884  1.00 45.31  ? 179 HIS   X N   1 
ATOM   1408 C  CA  . HIS   A 1 193 ? 7.661   -14.450 -4.199  1.00 55.24  ? 179 HIS   X CA  1 
ATOM   1409 C  C   . HIS   A 1 193 ? 8.808   -14.238 -5.213  1.00 59.04  ? 179 HIS   X C   1 
ATOM   1410 O  O   . HIS   A 1 193 ? 9.266   -15.191 -5.855  1.00 56.69  ? 179 HIS   X O   1 
ATOM   1411 C  CB  . HIS   A 1 193 ? 6.566   -15.498 -4.545  1.00 55.85  ? 179 HIS   X CB  1 
ATOM   1412 C  CG  . HIS   A 1 193 ? 5.625   -15.729 -3.399  1.00 62.25  ? 179 HIS   X CG  1 
ATOM   1413 N  ND1 . HIS   A 1 193 ? 6.086   -16.121 -2.131  1.00 63.12  ? 179 HIS   X ND1 1 
ATOM   1414 C  CD2 . HIS   A 1 193 ? 4.282   -15.542 -3.278  1.00 64.41  ? 179 HIS   X CD2 1 
ATOM   1415 C  CE1 . HIS   A 1 193 ? 5.060   -16.188 -1.288  1.00 59.33  ? 179 HIS   X CE1 1 
ATOM   1416 N  NE2 . HIS   A 1 193 ? 3.938   -15.836 -1.969  1.00 71.62  ? 179 HIS   X NE2 1 
ATOM   1417 N  N   . GLU   A 1 194 ? 9.340   -13.027 -5.313  1.00 45.17  ? 180 GLU   X N   1 
ATOM   1418 C  CA  . GLU   A 1 194 ? 10.306  -12.720 -6.385  1.00 43.49  ? 180 GLU   X CA  1 
ATOM   1419 C  C   . GLU   A 1 194 ? 11.686  -13.143 -5.944  1.00 47.85  ? 180 GLU   X C   1 
ATOM   1420 O  O   . GLU   A 1 194 ? 12.117  -12.757 -4.847  1.00 45.39  ? 180 GLU   X O   1 
ATOM   1421 C  CB  . GLU   A 1 194 ? 10.369  -11.238 -6.716  1.00 45.31  ? 180 GLU   X CB  1 
ATOM   1422 C  CG  . GLU   A 1 194 ? 10.924  -10.964 -8.093  1.00 44.46  ? 180 GLU   X CG  1 
ATOM   1423 C  CD  . GLU   A 1 194 ? 10.836  -9.510  -8.538  1.00 46.74  ? 180 GLU   X CD  1 
ATOM   1424 O  OE1 . GLU   A 1 194 ? 10.034  -8.731  -7.970  1.00 40.21  ? 180 GLU   X OE1 1 
ATOM   1425 O  OE2 . GLU   A 1 194 ? 11.588  -9.163  -9.446  1.00 48.56  ? 180 GLU   X OE2 1 
ATOM   1426 N  N   . ASP   A 1 195 ? 12.287  -13.910 -6.833  1.00 59.63  ? 181 ASP   X N   1 
ATOM   1427 C  CA  . ASP   A 1 195 ? 13.698  -14.338 -6.881  1.00 76.92  ? 181 ASP   X CA  1 
ATOM   1428 C  C   . ASP   A 1 195 ? 14.596  -13.179 -6.434  1.00 63.61  ? 181 ASP   X C   1 
ATOM   1429 O  O   . ASP   A 1 195 ? 14.098  -12.160 -6.000  1.00 81.18  ? 181 ASP   X O   1 
ATOM   1430 C  CB  . ASP   A 1 195 ? 14.009  -14.830 -8.309  1.00 84.18  ? 181 ASP   X CB  1 
ATOM   1431 C  CG  . ASP   A 1 195 ? 13.797  -16.320 -8.580  1.00 88.89  ? 181 ASP   X CG  1 
ATOM   1432 O  OD1 . ASP   A 1 195 ? 12.990  -16.969 -7.850  1.00 73.10  ? 181 ASP   X OD1 1 
ATOM   1433 O  OD2 . ASP   A 1 195 ? 14.447  -16.820 -9.535  1.00 82.21  ? 181 ASP   X OD2 1 
ATOM   1434 N  N   . ASN   A 1 196 ? 15.888  -13.384 -6.572  1.00 46.13  ? 182 ASN   X N   1 
ATOM   1435 C  CA  . ASN   A 1 196 ? 16.985  -12.475 -6.181  1.00 47.04  ? 182 ASN   X CA  1 
ATOM   1436 C  C   . ASN   A 1 196 ? 17.598  -11.817 -7.445  1.00 47.94  ? 182 ASN   X C   1 
ATOM   1437 O  O   . ASN   A 1 196 ? 18.185  -12.471 -8.339  1.00 46.64  ? 182 ASN   X O   1 
ATOM   1438 C  CB  . ASN   A 1 196 ? 18.114  -13.195 -5.492  1.00 57.04  ? 182 ASN   X CB  1 
ATOM   1439 C  CG  . ASN   A 1 196 ? 17.709  -14.066 -4.322  1.00 75.06  ? 182 ASN   X CG  1 
ATOM   1440 O  OD1 . ASN   A 1 196 ? 18.356  -15.125 -4.212  1.00 63.89  ? 182 ASN   X OD1 1 
ATOM   1441 N  ND2 . ASN   A 1 196 ? 16.701  -13.663 -3.499  1.00 52.87  ? 182 ASN   X ND2 1 
ATOM   1442 N  N   . ILE   A 1 197 ? 17.554  -10.512 -7.450  1.00 38.25  ? 183 ILE   X N   1 
ATOM   1443 C  CA  . ILE   A 1 197 ? 17.614  -9.655  -8.650  1.00 41.20  ? 183 ILE   X CA  1 
ATOM   1444 C  C   . ILE   A 1 197 ? 19.060  -9.278  -8.909  1.00 37.65  ? 183 ILE   X C   1 
ATOM   1445 O  O   . ILE   A 1 197 ? 19.689  -8.729  -7.992  1.00 35.54  ? 183 ILE   X O   1 
ATOM   1446 C  CB  . ILE   A 1 197 ? 16.736  -8.420  -8.430  1.00 45.05  ? 183 ILE   X CB  1 
ATOM   1447 C  CG1 . ILE   A 1 197 ? 15.294  -8.832  -8.129  1.00 51.73  ? 183 ILE   X CG1 1 
ATOM   1448 C  CG2 . ILE   A 1 197 ? 16.861  -7.456  -9.603  1.00 52.16  ? 183 ILE   X CG2 1 
ATOM   1449 C  CD1 . ILE   A 1 197 ? 14.527  -7.747  -7.407  1.00 56.09  ? 183 ILE   X CD1 1 
ATOM   1450 N  N   . LEU   A 1 198 ? 19.559  -9.629  -10.094 1.00 37.40  ? 184 LEU   X N   1 
ATOM   1451 C  CA  . LEU   A 1 198 ? 20.910  -9.262  -10.564 1.00 45.19  ? 184 LEU   X CA  1 
ATOM   1452 C  C   . LEU   A 1 198 ? 20.845  -7.774  -10.920 1.00 44.96  ? 184 LEU   X C   1 
ATOM   1453 O  O   . LEU   A 1 198 ? 20.080  -7.405  -11.764 1.00 44.62  ? 184 LEU   X O   1 
ATOM   1454 C  CB  . LEU   A 1 198 ? 21.311  -10.119 -11.765 1.00 50.80  ? 184 LEU   X CB  1 
ATOM   1455 C  CG  . LEU   A 1 198 ? 22.743  -9.850  -12.264 1.00 63.71  ? 184 LEU   X CG  1 
ATOM   1456 C  CD1 . LEU   A 1 198 ? 23.758  -10.251 -11.196 1.00 61.10  ? 184 LEU   X CD1 1 
ATOM   1457 C  CD2 . LEU   A 1 198 ? 23.050  -10.582 -13.573 1.00 67.94  ? 184 LEU   X CD2 1 
ATOM   1458 N  N   . LEU   A 1 199 ? 21.514  -6.909  -10.181 1.00 43.82  ? 185 LEU   X N   1 
ATOM   1459 C  CA  . LEU   A 1 199 ? 21.515  -5.458  -10.483 1.00 40.79  ? 185 LEU   X CA  1 
ATOM   1460 C  C   . LEU   A 1 199 ? 22.672  -5.107  -11.410 1.00 41.00  ? 185 LEU   X C   1 
ATOM   1461 O  O   . LEU   A 1 199 ? 22.536  -4.146  -12.159 1.00 47.31  ? 185 LEU   X O   1 
ATOM   1462 C  CB  . LEU   A 1 199 ? 21.668  -4.692  -9.172  1.00 42.63  ? 185 LEU   X CB  1 
ATOM   1463 C  CG  . LEU   A 1 199 ? 20.401  -4.276  -8.454  1.00 47.51  ? 185 LEU   X CG  1 
ATOM   1464 C  CD1 . LEU   A 1 199 ? 20.771  -3.293  -7.342  1.00 45.01  ? 185 LEU   X CD1 1 
ATOM   1465 C  CD2 . LEU   A 1 199 ? 19.380  -3.681  -9.425  1.00 49.04  ? 185 LEU   X CD2 1 
ATOM   1466 N  N   . ALA   A 1 200 ? 23.813  -5.787  -11.258 1.00 40.56  ? 186 ALA   X N   1 
ATOM   1467 C  CA  . ALA   A 1 200 ? 25.073  -5.531  -11.981 1.00 43.26  ? 186 ALA   X CA  1 
ATOM   1468 C  C   . ALA   A 1 200 ? 25.983  -6.725  -11.744 1.00 42.88  ? 186 ALA   X C   1 
ATOM   1469 O  O   . ALA   A 1 200 ? 25.666  -7.529  -10.884 1.00 37.81  ? 186 ALA   X O   1 
ATOM   1470 C  CB  . ALA   A 1 200 ? 25.694  -4.224  -11.519 1.00 44.53  ? 186 ALA   X CB  1 
ATOM   1471 N  N   . GLU   A 1 201 ? 27.049  -6.875  -12.510 1.00 39.32  ? 187 GLU   X N   1 
ATOM   1472 C  CA  . GLU   A 1 201 ? 27.999  -7.986  -12.284 1.00 41.08  ? 187 GLU   X CA  1 
ATOM   1473 C  C   . GLU   A 1 201 ? 28.409  -8.038  -10.801 1.00 42.01  ? 187 GLU   X C   1 
ATOM   1474 O  O   . GLU   A 1 201 ? 28.880  -7.011  -10.270 1.00 40.09  ? 187 GLU   X O   1 
ATOM   1475 C  CB  . GLU   A 1 201 ? 29.224  -7.802  -13.180 1.00 45.76  ? 187 GLU   X CB  1 
ATOM   1476 C  CG  . GLU   A 1 201 ? 30.019  -9.078  -13.354 1.00 50.41  ? 187 GLU   X CG  1 
ATOM   1477 C  CD  . GLU   A 1 201 ? 31.312  -8.812  -14.097 1.00 56.81  ? 187 GLU   X CD  1 
ATOM   1478 O  OE1 . GLU   A 1 201 ? 31.438  -7.701  -14.676 1.00 60.00  ? 187 GLU   X OE1 1 
ATOM   1479 O  OE2 . GLU   A 1 201 ? 32.177  -9.697  -14.088 1.00 62.49  ? 187 GLU   X OE2 1 
ATOM   1480 N  N   . GLY   A 1 202 ? 28.201  -9.196  -10.169 1.00 38.81  ? 188 GLY   X N   1 
ATOM   1481 C  CA  . GLY   A 1 202 ? 28.515  -9.473  -8.759  1.00 39.82  ? 188 GLY   X CA  1 
ATOM   1482 C  C   . GLY   A 1 202 ? 27.686  -8.686  -7.762  1.00 39.75  ? 188 GLY   X C   1 
ATOM   1483 O  O   . GLY   A 1 202 ? 28.175  -8.547  -6.646  1.00 39.50  ? 188 GLY   X O   1 
ATOM   1484 N  N   . VAL   A 1 203 ? 26.508  -8.157  -8.132  1.00 36.45  ? 189 VAL   X N   1 
ATOM   1485 C  CA  . VAL   A 1 203 ? 25.617  -7.434  -7.182  1.00 36.21  ? 189 VAL   X CA  1 
ATOM   1486 C  C   . VAL   A 1 203 ? 24.193  -7.995  -7.334  1.00 37.52  ? 189 VAL   X C   1 
ATOM   1487 O  O   . VAL   A 1 203 ? 23.571  -7.826  -8.413  1.00 35.65  ? 189 VAL   X O   1 
ATOM   1488 C  CB  . VAL   A 1 203 ? 25.618  -5.908  -7.354  1.00 38.27  ? 189 VAL   X CB  1 
ATOM   1489 C  CG1 . VAL   A 1 203 ? 24.755  -5.277  -6.278  1.00 38.42  ? 189 VAL   X CG1 1 
ATOM   1490 C  CG2 . VAL   A 1 203 ? 27.037  -5.327  -7.294  1.00 37.10  ? 189 VAL   X CG2 1 
ATOM   1491 N  N   . LYS   A 1 204 ? 23.709  -8.619  -6.273  1.00 36.19  ? 190 LYS   X N   1 
ATOM   1492 C  CA  . LYS   A 1 204 ? 22.425  -9.342  -6.269  1.00 40.15  ? 190 LYS   X CA  1 
ATOM   1493 C  C   . LYS   A 1 204 ? 21.605  -8.767  -5.109  1.00 33.92  ? 190 LYS   X C   1 
ATOM   1494 O  O   . LYS   A 1 204 ? 22.134  -8.757  -3.976  1.00 35.99  ? 190 LYS   X O   1 
ATOM   1495 C  CB  . LYS   A 1 204 ? 22.747  -10.835 -6.133  1.00 40.48  ? 190 LYS   X CB  1 
ATOM   1496 C  CG  . LYS   A 1 204 ? 21.593  -11.782 -6.352  1.00 53.51  ? 190 LYS   X CG  1 
ATOM   1497 C  CD  . LYS   A 1 204 ? 21.807  -13.159 -5.767  1.00 56.97  ? 190 LYS   X CD  1 
ATOM   1498 C  CE  . LYS   A 1 204 ? 22.904  -13.921 -6.459  1.00 66.06  ? 190 LYS   X CE  1 
ATOM   1499 N  NZ  . LYS   A 1 204 ? 22.871  -15.321 -5.989  1.00 66.54  ? 190 LYS   X NZ  1 
ATOM   1500 N  N   . VAL   A 1 205 ? 20.344  -8.414  -5.361  1.00 34.14  ? 191 VAL   X N   1 
ATOM   1501 C  CA  . VAL   A 1 205 ? 19.388  -8.066  -4.281  1.00 32.64  ? 191 VAL   X CA  1 
ATOM   1502 C  C   . VAL   A 1 205 ? 18.816  -9.370  -3.740  1.00 32.42  ? 191 VAL   X C   1 
ATOM   1503 O  O   . VAL   A 1 205 ? 18.240  -10.152 -4.541  1.00 37.22  ? 191 VAL   X O   1 
ATOM   1504 C  CB  . VAL   A 1 205 ? 18.267  -7.122  -4.763  1.00 35.50  ? 191 VAL   X CB  1 
ATOM   1505 C  CG1 . VAL   A 1 205 ? 17.336  -6.805  -3.596  1.00 38.05  ? 191 VAL   X CG1 1 
ATOM   1506 C  CG2 . VAL   A 1 205 ? 18.800  -5.865  -5.408  1.00 34.32  ? 191 VAL   X CG2 1 
ATOM   1507 N  N   . LEU   A 1 206 ? 18.883  -9.570  -2.440  1.00 34.82  ? 192 LEU   X N   1 
ATOM   1508 C  CA  . LEU   A 1 206 ? 18.301  -10.744 -1.756  1.00 32.74  ? 192 LEU   X CA  1 
ATOM   1509 C  C   . LEU   A 1 206 ? 16.930  -10.352 -1.197  1.00 31.78  ? 192 LEU   X C   1 
ATOM   1510 O  O   . LEU   A 1 206 ? 16.832  -9.402  -0.418  1.00 34.86  ? 192 LEU   X O   1 
ATOM   1511 C  CB  . LEU   A 1 206 ? 19.217  -11.163 -0.624  1.00 32.35  ? 192 LEU   X CB  1 
ATOM   1512 C  CG  . LEU   A 1 206 ? 20.646  -11.508 -1.042  1.00 39.06  ? 192 LEU   X CG  1 
ATOM   1513 C  CD1 . LEU   A 1 206 ? 21.539  -11.659 0.183   1.00 39.11  ? 192 LEU   X CD1 1 
ATOM   1514 C  CD2 . LEU   A 1 206 ? 20.677  -12.783 -1.880  1.00 40.69  ? 192 LEU   X CD2 1 
ATOM   1515 N  N   . ASN   A 1 207 ? 15.911  -11.123 -1.485  1.00 31.11  ? 193 ASN   X N   1 
ATOM   1516 C  CA  . ASN   A 1 207 ? 14.572  -10.875 -0.918  1.00 34.62  ? 193 ASN   X CA  1 
ATOM   1517 C  C   . ASN   A 1 207 ? 14.438  -11.710 0.351   1.00 35.35  ? 193 ASN   X C   1 
ATOM   1518 O  O   . ASN   A 1 207 ? 14.129  -12.919 0.266   1.00 31.84  ? 193 ASN   X O   1 
ATOM   1519 C  CB  . ASN   A 1 207 ? 13.490  -11.181 -1.937  1.00 37.29  ? 193 ASN   X CB  1 
ATOM   1520 C  CG  . ASN   A 1 207 ? 12.097  -10.889 -1.407  1.00 30.89  ? 193 ASN   X CG  1 
ATOM   1521 O  OD1 . ASN   A 1 207 ? 11.919  -10.553 -0.247  1.00 33.97  ? 193 ASN   X OD1 1 
ATOM   1522 N  ND2 . ASN   A 1 207 ? 11.105  -11.199 -2.199  1.00 38.20  ? 193 ASN   X ND2 1 
ATOM   1523 N  N   . PHE   A 1 208 ? 14.677  -11.086 1.496   1.00 32.62  ? 194 PHE   X N   1 
ATOM   1524 C  CA  . PHE   A 1 208 ? 14.555  -11.747 2.821   1.00 34.61  ? 194 PHE   X CA  1 
ATOM   1525 C  C   . PHE   A 1 208 ? 13.088  -11.926 3.240   1.00 35.80  ? 194 PHE   X C   1 
ATOM   1526 O  O   . PHE   A 1 208 ? 12.811  -12.799 4.057   1.00 35.67  ? 194 PHE   X O   1 
ATOM   1527 C  CB  . PHE   A 1 208 ? 15.363  -11.000 3.876   1.00 35.12  ? 194 PHE   X CB  1 
ATOM   1528 C  CG  . PHE   A 1 208 ? 16.862  -10.990 3.665   1.00 35.98  ? 194 PHE   X CG  1 
ATOM   1529 C  CD1 . PHE   A 1 208 ? 17.544  -12.108 3.164   1.00 33.63  ? 194 PHE   X CD1 1 
ATOM   1530 C  CD2 . PHE   A 1 208 ? 17.602  -9.894  4.093   1.00 38.67  ? 194 PHE   X CD2 1 
ATOM   1531 C  CE1 . PHE   A 1 208 ? 18.922  -12.092 3.048   1.00 32.22  ? 194 PHE   X CE1 1 
ATOM   1532 C  CE2 . PHE   A 1 208 ? 18.979  -9.880  3.955   1.00 34.03  ? 194 PHE   X CE2 1 
ATOM   1533 C  CZ  . PHE   A 1 208 ? 19.631  -10.974 3.432   1.00 33.22  ? 194 PHE   X CZ  1 
ATOM   1534 N  N   . GLY   A 1 209 ? 12.176  -11.102 2.736   1.00 36.67  ? 195 GLY   X N   1 
ATOM   1535 C  CA  . GLY   A 1 209 ? 10.758  -11.125 3.106   1.00 37.51  ? 195 GLY   X CA  1 
ATOM   1536 C  C   . GLY   A 1 209 ? 10.521  -10.571 4.501   1.00 34.64  ? 195 GLY   X C   1 
ATOM   1537 O  O   . GLY   A 1 209 ? 11.383  -9.827  5.024   1.00 33.11  ? 195 GLY   X O   1 
ATOM   1538 N  N   . SER   A 1 210 ? 9.384   -10.925 5.105   1.00 33.06  ? 196 SER   X N   1 
ATOM   1539 C  CA  . SER   A 1 210 ? 8.919   -10.336 6.384   1.00 32.53  ? 196 SER   X CA  1 
ATOM   1540 C  C   . SER   A 1 210 ? 9.789   -10.896 7.514   1.00 32.88  ? 196 SER   X C   1 
ATOM   1541 O  O   . SER   A 1 210 ? 10.264  -12.048 7.423   1.00 32.92  ? 196 SER   X O   1 
ATOM   1542 C  CB  . SER   A 1 210 ? 7.445   -10.623 6.622   1.00 32.91  ? 196 SER   X CB  1 
ATOM   1543 O  OG  . SER   A 1 210 ? 7.187   -11.995 6.374   1.00 32.09  ? 196 SER   X OG  1 
ATOM   1544 N  N   . GLY   A 1 211 ? 10.047  -10.076 8.518   1.00 33.01  ? 197 GLY   X N   1 
ATOM   1545 C  CA  . GLY   A 1 211 ? 10.790  -10.471 9.709   1.00 33.68  ? 197 GLY   X CA  1 
ATOM   1546 C  C   . GLY   A 1 211 ? 10.859  -9.316  10.670  1.00 32.69  ? 197 GLY   X C   1 
ATOM   1547 O  O   . GLY   A 1 211 ? 9.837   -9.012  11.300  1.00 32.20  ? 197 GLY   X O   1 
ATOM   1548 N  N   . HIS   A 1 212 ? 11.993  -8.613  10.690  1.00 31.02  ? 198 HIS   X N   1 
ATOM   1549 C  CA  . HIS   A 1 212 ? 12.146  -7.345  11.436  1.00 32.00  ? 198 HIS   X CA  1 
ATOM   1550 C  C   . HIS   A 1 212 ? 11.015  -6.378  11.060  1.00 34.32  ? 198 HIS   X C   1 
ATOM   1551 O  O   . HIS   A 1 212 ? 10.434  -5.833  11.964  1.00 33.80  ? 198 HIS   X O   1 
ATOM   1552 C  CB  . HIS   A 1 212 ? 13.508  -6.707  11.122  1.00 33.51  ? 198 HIS   X CB  1 
ATOM   1553 C  CG  . HIS   A 1 212 ? 13.697  -5.306  11.578  1.00 33.27  ? 198 HIS   X CG  1 
ATOM   1554 N  ND1 . HIS   A 1 212 ? 13.929  -5.025  12.903  1.00 34.31  ? 198 HIS   X ND1 1 
ATOM   1555 C  CD2 . HIS   A 1 212 ? 13.715  -4.120  10.909  1.00 34.96  ? 198 HIS   X CD2 1 
ATOM   1556 C  CE1 . HIS   A 1 212 ? 14.091  -3.710  13.046  1.00 35.99  ? 198 HIS   X CE1 1 
ATOM   1557 N  NE2 . HIS   A 1 212 ? 13.987  -3.129  11.831  1.00 36.07  ? 198 HIS   X NE2 1 
ATOM   1558 N  N   . ALA   A 1 213 ? 10.758  -6.185  9.769   1.00 33.89  ? 199 ALA   X N   1 
ATOM   1559 C  CA  . ALA   A 1 213 ? 9.699   -5.291  9.245   1.00 37.16  ? 199 ALA   X CA  1 
ATOM   1560 C  C   . ALA   A 1 213 ? 8.834   -6.080  8.246   1.00 31.50  ? 199 ALA   X C   1 
ATOM   1561 O  O   . ALA   A 1 213 ? 9.010   -7.346  8.140   1.00 33.27  ? 199 ALA   X O   1 
ATOM   1562 C  CB  . ALA   A 1 213 ? 10.312  -4.033  8.659   1.00 34.75  ? 199 ALA   X CB  1 
ATOM   1563 N  N   . TRP   A 1 214 ? 7.928   -5.399  7.561   1.00 31.38  ? 200 TRP   X N   1 
ATOM   1564 C  CA  . TRP   A 1 214 ? 7.024   -6.024  6.551   1.00 33.03  ? 200 TRP   X CA  1 
ATOM   1565 C  C   . TRP   A 1 214 ? 7.819   -6.729  5.458   1.00 33.78  ? 200 TRP   X C   1 
ATOM   1566 O  O   . TRP   A 1 214 ? 7.391   -7.780  5.023   1.00 31.58  ? 200 TRP   X O   1 
ATOM   1567 C  CB  . TRP   A 1 214 ? 6.052   -5.014  5.954   1.00 31.44  ? 200 TRP   X CB  1 
ATOM   1568 C  CG  . TRP   A 1 214 ? 5.116   -4.432  6.970   1.00 36.31  ? 200 TRP   X CG  1 
ATOM   1569 C  CD1 . TRP   A 1 214 ? 4.241   -5.131  7.740   1.00 38.97  ? 200 TRP   X CD1 1 
ATOM   1570 C  CD2 . TRP   A 1 214 ? 4.961   -3.047  7.332   1.00 35.81  ? 200 TRP   X CD2 1 
ATOM   1571 N  NE1 . TRP   A 1 214 ? 3.577   -4.282  8.584   1.00 39.99  ? 200 TRP   X NE1 1 
ATOM   1572 C  CE2 . TRP   A 1 214 ? 3.987   -3.002  8.353   1.00 40.48  ? 200 TRP   X CE2 1 
ATOM   1573 C  CE3 . TRP   A 1 214 ? 5.553   -1.845  6.916   1.00 35.69  ? 200 TRP   X CE3 1 
ATOM   1574 C  CZ2 . TRP   A 1 214 ? 3.562   -1.802  8.932   1.00 41.73  ? 200 TRP   X CZ2 1 
ATOM   1575 C  CZ3 . TRP   A 1 214 ? 5.137   -0.665  7.490   1.00 36.65  ? 200 TRP   X CZ3 1 
ATOM   1576 C  CH2 . TRP   A 1 214 ? 4.146   -0.640  8.478   1.00 37.31  ? 200 TRP   X CH2 1 
ATOM   1577 N  N   . GLY   A 1 215 ? 8.910   -6.144  4.976   1.00 29.44  ? 201 GLY   X N   1 
ATOM   1578 C  CA  . GLY   A 1 215 ? 9.655   -6.727  3.850   1.00 30.57  ? 201 GLY   X CA  1 
ATOM   1579 C  C   . GLY   A 1 215 ? 11.094  -6.235  3.801   1.00 31.95  ? 201 GLY   X C   1 
ATOM   1580 O  O   . GLY   A 1 215 ? 11.310  -5.032  3.617   1.00 32.89  ? 201 GLY   X O   1 
ATOM   1581 N  N   . MET   A 1 216 ? 12.040  -7.149  3.968   1.00 33.06  ? 202 MET   X N   1 
ATOM   1582 C  CA  . MET   A 1 216 ? 13.467  -6.829  4.153   1.00 32.64  ? 202 MET   X CA  1 
ATOM   1583 C  C   . MET   A 1 216 ? 14.220  -7.187  2.855   1.00 35.47  ? 202 MET   X C   1 
ATOM   1584 O  O   . MET   A 1 216 ? 13.992  -8.280  2.309   1.00 31.77  ? 202 MET   X O   1 
ATOM   1585 C  CB  . MET   A 1 216 ? 14.070  -7.596  5.336   1.00 32.57  ? 202 MET   X CB  1 
ATOM   1586 C  CG  . MET   A 1 216 ? 13.369  -7.401  6.663   1.00 33.96  ? 202 MET   X CG  1 
ATOM   1587 S  SD  . MET   A 1 216 ? 13.366  -5.701  7.217   1.00 36.95  ? 202 MET   X SD  1 
ATOM   1588 C  CE  . MET   A 1 216 ? 15.086  -5.376  7.603   1.00 36.61  ? 202 MET   X CE  1 
ATOM   1589 N  N   . LEU   A 1 217 ? 15.106  -6.295  2.387   1.00 30.30  ? 203 LEU   X N   1 
ATOM   1590 C  CA  . LEU   A 1 217 ? 16.033  -6.635  1.271   1.00 30.42  ? 203 LEU   X CA  1 
ATOM   1591 C  C   . LEU   A 1 217 ? 17.456  -6.588  1.786   1.00 33.43  ? 203 LEU   X C   1 
ATOM   1592 O  O   . LEU   A 1 217 ? 17.775  -5.753  2.665   1.00 31.61  ? 203 LEU   X O   1 
ATOM   1593 C  CB  . LEU   A 1 217 ? 15.879  -5.700  0.079   1.00 31.94  ? 203 LEU   X CB  1 
ATOM   1594 C  CG  . LEU   A 1 217 ? 14.483  -5.550  -0.507  1.00 35.36  ? 203 LEU   X CG  1 
ATOM   1595 C  CD1 . LEU   A 1 217 ? 14.507  -4.509  -1.649  1.00 34.14  ? 203 LEU   X CD1 1 
ATOM   1596 C  CD2 . LEU   A 1 217 ? 13.970  -6.900  -0.983  1.00 32.90  ? 203 LEU   X CD2 1 
ATOM   1597 N  N   . GLY   A 1 218 ? 18.250  -7.520  1.285   1.00 34.16  ? 204 GLY   X N   1 
ATOM   1598 C  CA  . GLY   A 1 218 ? 19.675  -7.521  1.533   1.00 31.22  ? 204 GLY   X CA  1 
ATOM   1599 C  C   . GLY   A 1 218 ? 20.382  -7.360  0.218   1.00 30.58  ? 204 GLY   X C   1 
ATOM   1600 O  O   . GLY   A 1 218 ? 19.711  -7.341  -0.810  1.00 32.31  ? 204 GLY   X O   1 
ATOM   1601 N  N   . LEU   A 1 219 ? 21.706  -7.388  0.263   1.00 32.01  ? 205 LEU   X N   1 
ATOM   1602 C  CA  . LEU   A 1 219 ? 22.569  -7.331  -0.927  1.00 33.07  ? 205 LEU   X CA  1 
ATOM   1603 C  C   . LEU   A 1 219 ? 23.656  -8.383  -0.773  1.00 35.20  ? 205 LEU   X C   1 
ATOM   1604 O  O   . LEU   A 1 219 ? 24.185  -8.525  0.323   1.00 32.61  ? 205 LEU   X O   1 
ATOM   1605 C  CB  . LEU   A 1 219 ? 23.138  -5.915  -1.051  1.00 34.99  ? 205 LEU   X CB  1 
ATOM   1606 C  CG  . LEU   A 1 219 ? 23.326  -5.401  -2.477  1.00 40.64  ? 205 LEU   X CG  1 
ATOM   1607 C  CD1 . LEU   A 1 219 ? 21.987  -5.220  -3.195  1.00 38.54  ? 205 LEU   X CD1 1 
ATOM   1608 C  CD2 . LEU   A 1 219 ? 24.094  -4.072  -2.481  1.00 42.35  ? 205 LEU   X CD2 1 
ATOM   1609 N  N   . HIS   A 1 220 ? 23.933  -9.105  -1.837  1.00 31.06  ? 206 HIS   X N   1 
ATOM   1610 C  CA  . HIS   A 1 220 ? 25.136  -9.964  -1.904  1.00 32.36  ? 206 HIS   X CA  1 
ATOM   1611 C  C   . HIS   A 1 220 ? 26.062  -9.358  -2.955  1.00 35.80  ? 206 HIS   X C   1 
ATOM   1612 O  O   . HIS   A 1 220 ? 25.655  -9.224  -4.105  1.00 36.79  ? 206 HIS   X O   1 
ATOM   1613 C  CB  . HIS   A 1 220 ? 24.819  -11.429 -2.174  1.00 37.31  ? 206 HIS   X CB  1 
ATOM   1614 C  CG  . HIS   A 1 220 ? 26.092  -12.205 -2.089  1.00 49.32  ? 206 HIS   X CG  1 
ATOM   1615 N  ND1 . HIS   A 1 220 ? 27.049  -12.174 -3.118  1.00 60.62  ? 206 HIS   X ND1 1 
ATOM   1616 C  CD2 . HIS   A 1 220 ? 26.670  -12.855 -1.064  1.00 50.34  ? 206 HIS   X CD2 1 
ATOM   1617 C  CE1 . HIS   A 1 220 ? 28.116  -12.854 -2.740  1.00 54.35  ? 206 HIS   X CE1 1 
ATOM   1618 N  NE2 . HIS   A 1 220 ? 27.893  -13.278 -1.476  1.00 50.39  ? 206 HIS   X NE2 1 
ATOM   1619 N  N   . VAL   A 1 221 ? 27.226  -8.909  -2.512  1.00 36.52  ? 207 VAL   X N   1 
ATOM   1620 C  CA  . VAL   A 1 221 ? 28.240  -8.255  -3.379  1.00 34.76  ? 207 VAL   X CA  1 
ATOM   1621 C  C   . VAL   A 1 221 ? 29.427  -9.214  -3.510  1.00 34.30  ? 207 VAL   X C   1 
ATOM   1622 O  O   . VAL   A 1 221 ? 29.966  -9.656  -2.474  1.00 37.23  ? 207 VAL   X O   1 
ATOM   1623 C  CB  . VAL   A 1 221 ? 28.643  -6.907  -2.765  1.00 36.70  ? 207 VAL   X CB  1 
ATOM   1624 C  CG1 . VAL   A 1 221 ? 29.703  -6.214  -3.610  1.00 37.97  ? 207 VAL   X CG1 1 
ATOM   1625 C  CG2 . VAL   A 1 221 ? 27.427  -6.009  -2.618  1.00 39.85  ? 207 VAL   X CG2 1 
ATOM   1626 N  N   . GLU   A 1 222 ? 29.857  -9.485  -4.728  1.00 34.04  ? 208 GLU   X N   1 
ATOM   1627 C  CA  . GLU   A 1 222 ? 31.072  -10.302 -4.973  1.00 39.60  ? 208 GLU   X CA  1 
ATOM   1628 C  C   . GLU   A 1 222 ? 32.162  -9.339  -5.493  1.00 38.25  ? 208 GLU   X C   1 
ATOM   1629 O  O   . GLU   A 1 222 ? 32.063  -8.900  -6.649  1.00 37.75  ? 208 GLU   X O   1 
ATOM   1630 C  CB  . GLU   A 1 222 ? 30.764  -11.483 -5.904  1.00 38.55  ? 208 GLU   X CB  1 
ATOM   1631 C  CG  . GLU   A 1 222 ? 31.967  -12.416 -6.080  1.00 47.67  ? 208 GLU   X CG  1 
ATOM   1632 C  CD  . GLU   A 1 222 ? 32.313  -13.196 -4.815  1.00 52.01  ? 208 GLU   X CD  1 
ATOM   1633 O  OE1 . GLU   A 1 222 ? 31.378  -13.534 -4.070  1.00 56.35  ? 208 GLU   X OE1 1 
ATOM   1634 O  OE2 . GLU   A 1 222 ? 33.513  -13.439 -4.560  1.00 58.36  ? 208 GLU   X OE2 1 
ATOM   1635 N  N   . LEU   A 1 223 ? 33.149  -8.995  -4.668  1.00 39.30  ? 209 LEU   X N   1 
ATOM   1636 C  CA  . LEU   A 1 223 ? 34.266  -8.116  -5.123  1.00 40.97  ? 209 LEU   X CA  1 
ATOM   1637 C  C   . LEU   A 1 223 ? 35.468  -8.984  -5.495  1.00 40.16  ? 209 LEU   X C   1 
ATOM   1638 O  O   . LEU   A 1 223 ? 35.785  -9.900  -4.761  1.00 41.24  ? 209 LEU   X O   1 
ATOM   1639 C  CB  . LEU   A 1 223 ? 34.653  -7.157  -4.003  1.00 39.87  ? 209 LEU   X CB  1 
ATOM   1640 C  CG  . LEU   A 1 223 ? 33.578  -6.168  -3.573  1.00 42.92  ? 209 LEU   X CG  1 
ATOM   1641 C  CD1 . LEU   A 1 223 ? 34.026  -5.455  -2.331  1.00 43.40  ? 209 LEU   X CD1 1 
ATOM   1642 C  CD2 . LEU   A 1 223 ? 33.267  -5.182  -4.694  1.00 44.76  ? 209 LEU   X CD2 1 
ATOM   1643 N  N   . PRO   A 1 224 ? 36.221  -8.639  -6.558  1.00 41.69  ? 210 PRO   X N   1 
ATOM   1644 C  CA  . PRO   A 1 224 ? 37.404  -9.397  -6.975  1.00 48.95  ? 210 PRO   X CA  1 
ATOM   1645 C  C   . PRO   A 1 224 ? 38.479  -9.609  -5.905  1.00 46.36  ? 210 PRO   X C   1 
ATOM   1646 O  O   . PRO   A 1 224 ? 38.987  -10.686 -5.852  1.00 47.83  ? 210 PRO   X O   1 
ATOM   1647 C  CB  . PRO   A 1 224 ? 38.066  -8.521  -8.052  1.00 49.74  ? 210 PRO   X CB  1 
ATOM   1648 C  CG  . PRO   A 1 224 ? 36.961  -7.605  -8.539  1.00 54.30  ? 210 PRO   X CG  1 
ATOM   1649 C  CD  . PRO   A 1 224 ? 35.967  -7.467  -7.408  1.00 50.35  ? 210 PRO   X CD  1 
ATOM   1650 N  N   . GLU   A 1 225 ? 38.793  -8.581  -5.097  1.00 46.29  ? 211 GLU   X N   1 
ATOM   1651 C  CA  . GLU   A 1 225 ? 39.862  -8.676  -4.075  1.00 51.97  ? 211 GLU   X CA  1 
ATOM   1652 C  C   . GLU   A 1 225 ? 39.263  -9.150  -2.761  1.00 50.14  ? 211 GLU   X C   1 
ATOM   1653 O  O   . GLU   A 1 225 ? 39.860  -10.023 -2.142  1.00 47.89  ? 211 GLU   X O   1 
ATOM   1654 C  CB  . GLU   A 1 225 ? 40.630  -7.358  -3.878  1.00 57.39  ? 211 GLU   X CB  1 
ATOM   1655 C  CG  . GLU   A 1 225 ? 41.269  -6.833  -5.151  1.00 88.73  ? 211 GLU   X CG  1 
ATOM   1656 C  CD  . GLU   A 1 225 ? 42.306  -7.736  -5.819  1.00 109.20 ? 211 GLU   X CD  1 
ATOM   1657 O  OE1 . GLU   A 1 225 ? 42.841  -7.321  -6.869  1.00 120.04 ? 211 GLU   X OE1 1 
ATOM   1658 O  OE2 . GLU   A 1 225 ? 42.587  -8.849  -5.297  1.00 113.68 ? 211 GLU   X OE2 1 
ATOM   1659 N  N   . THR   A 1 226 ? 38.149  -8.563  -2.328  1.00 43.76  ? 212 THR   X N   1 
ATOM   1660 C  CA  . THR   A 1 226 ? 37.628  -8.753  -0.960  1.00 42.46  ? 212 THR   X CA  1 
ATOM   1661 C  C   . THR   A 1 226 ? 36.851  -10.085 -0.909  1.00 39.62  ? 212 THR   X C   1 
ATOM   1662 O  O   . THR   A 1 226 ? 36.806  -10.680 0.170   1.00 40.59  ? 212 THR   X O   1 
ATOM   1663 C  CB  . THR   A 1 226 ? 36.843  -7.508  -0.517  1.00 46.34  ? 212 THR   X CB  1 
ATOM   1664 O  OG1 . THR   A 1 226 ? 37.680  -6.344  -0.549  1.00 48.80  ? 212 THR   X OG1 1 
ATOM   1665 C  CG2 . THR   A 1 226 ? 36.299  -7.628  0.888   1.00 43.84  ? 212 THR   X CG2 1 
ATOM   1666 N  N   . GLY   A 1 227 ? 36.279  -10.539 -2.025  1.00 40.67  ? 213 GLY   X N   1 
ATOM   1667 C  CA  . GLY   A 1 227 ? 35.381  -11.711 -2.064  1.00 40.81  ? 213 GLY   X CA  1 
ATOM   1668 C  C   . GLY   A 1 227 ? 33.959  -11.310 -1.704  1.00 39.87  ? 213 GLY   X C   1 
ATOM   1669 O  O   . GLY   A 1 227 ? 33.556  -10.192 -2.066  1.00 38.91  ? 213 GLY   X O   1 
ATOM   1670 N  N   . GLY   A 1 228 ? 33.200  -12.199 -1.042  1.00 41.83  ? 214 GLY   X N   1 
ATOM   1671 C  CA  . GLY   A 1 228 ? 31.743  -12.045 -0.840  1.00 38.45  ? 214 GLY   X CA  1 
ATOM   1672 C  C   . GLY   A 1 228 ? 31.382  -11.231 0.404   1.00 36.17  ? 214 GLY   X C   1 
ATOM   1673 O  O   . GLY   A 1 228 ? 32.016  -11.391 1.462   1.00 34.73  ? 214 GLY   X O   1 
ATOM   1674 N  N   . ILE   A 1 229 ? 30.389  -10.348 0.280   1.00 34.00  ? 215 ILE   X N   1 
ATOM   1675 C  CA  . ILE   A 1 229 ? 29.848  -9.528  1.394   1.00 35.62  ? 215 ILE   X CA  1 
ATOM   1676 C  C   . ILE   A 1 229 ? 28.328  -9.658  1.338   1.00 34.09  ? 215 ILE   X C   1 
ATOM   1677 O  O   . ILE   A 1 229 ? 27.765  -9.353  0.256   1.00 34.94  ? 215 ILE   X O   1 
ATOM   1678 C  CB  . ILE   A 1 229 ? 30.275  -8.058  1.274   1.00 34.63  ? 215 ILE   X CB  1 
ATOM   1679 C  CG1 . ILE   A 1 229 ? 31.807  -7.899  1.221   1.00 39.09  ? 215 ILE   X CG1 1 
ATOM   1680 C  CG2 . ILE   A 1 229 ? 29.642  -7.234  2.396   1.00 39.38  ? 215 ILE   X CG2 1 
ATOM   1681 C  CD1 . ILE   A 1 229 ? 32.263  -6.499  0.923   1.00 41.96  ? 215 ILE   X CD1 1 
ATOM   1682 N  N   . ILE   A 1 230 ? 27.704  -9.999  2.466   1.00 33.76  ? 216 ILE   X N   1 
ATOM   1683 C  CA  . ILE   A 1 230 ? 26.236  -9.909  2.631   1.00 33.48  ? 216 ILE   X CA  1 
ATOM   1684 C  C   . ILE   A 1 230 ? 25.914  -8.655  3.446   1.00 32.11  ? 216 ILE   X C   1 
ATOM   1685 O  O   . ILE   A 1 230 ? 26.366  -8.568  4.584   1.00 33.70  ? 216 ILE   X O   1 
ATOM   1686 C  CB  . ILE   A 1 230 ? 25.660  -11.191 3.238   1.00 35.97  ? 216 ILE   X CB  1 
ATOM   1687 C  CG1 . ILE   A 1 230 ? 25.926  -12.415 2.357   1.00 40.26  ? 216 ILE   X CG1 1 
ATOM   1688 C  CG2 . ILE   A 1 230 ? 24.174  -11.023 3.515   1.00 36.93  ? 216 ILE   X CG2 1 
ATOM   1689 C  CD1 . ILE   A 1 230 ? 25.956  -13.757 3.144   1.00 39.90  ? 216 ILE   X CD1 1 
ATOM   1690 N  N   . LEU   A 1 231 ? 25.162  -7.700  2.881   1.00 32.13  ? 217 LEU   X N   1 
ATOM   1691 C  CA  . LEU   A 1 231 ? 24.593  -6.575  3.661   1.00 32.89  ? 217 LEU   X CA  1 
ATOM   1692 C  C   . LEU   A 1 231 ? 23.244  -7.030  4.191   1.00 33.60  ? 217 LEU   X C   1 
ATOM   1693 O  O   . LEU   A 1 231 ? 22.294  -7.184  3.385   1.00 34.36  ? 217 LEU   X O   1 
ATOM   1694 C  CB  . LEU   A 1 231 ? 24.460  -5.331  2.786   1.00 34.58  ? 217 LEU   X CB  1 
ATOM   1695 C  CG  . LEU   A 1 231 ? 25.742  -4.910  2.065   1.00 36.91  ? 217 LEU   X CG  1 
ATOM   1696 C  CD1 . LEU   A 1 231 ? 25.527  -3.630  1.280   1.00 40.27  ? 217 LEU   X CD1 1 
ATOM   1697 C  CD2 . LEU   A 1 231 ? 26.901  -4.759  3.036   1.00 35.73  ? 217 LEU   X CD2 1 
ATOM   1698 N  N   . ALA   A 1 232 ? 23.184  -7.282  5.481   1.00 33.33  ? 218 ALA   X N   1 
ATOM   1699 C  CA  . ALA   A 1 232 ? 21.987  -7.840  6.146   1.00 36.52  ? 218 ALA   X CA  1 
ATOM   1700 C  C   . ALA   A 1 232 ? 21.049  -6.732  6.621   1.00 34.77  ? 218 ALA   X C   1 
ATOM   1701 O  O   . ALA   A 1 232 ? 19.861  -7.036  6.905   1.00 34.80  ? 218 ALA   X O   1 
ATOM   1702 C  CB  . ALA   A 1 232 ? 22.449  -8.705  7.288   1.00 37.87  ? 218 ALA   X CB  1 
ATOM   1703 N  N   . SER   A 1 233 ? 21.572  -5.520  6.839   1.00 34.91  ? 219 SER   X N   1 
ATOM   1704 C  CA  . SER   A 1 233 ? 20.825  -4.419  7.492   1.00 35.31  ? 219 SER   X CA  1 
ATOM   1705 C  C   . SER   A 1 233 ? 20.131  -4.975  8.762   1.00 36.60  ? 219 SER   X C   1 
ATOM   1706 O  O   . SER   A 1 233 ? 20.756  -5.794  9.487   1.00 32.79  ? 219 SER   X O   1 
ATOM   1707 C  CB  . SER   A 1 233 ? 19.845  -3.799  6.515   1.00 38.44  ? 219 SER   X CB  1 
ATOM   1708 O  OG  . SER   A 1 233 ? 19.100  -2.747  7.123   1.00 36.28  ? 219 SER   X OG  1 
ATOM   1709 N  N   . ASP   A 1 234 ? 18.871  -4.614  9.026   1.00 35.00  ? 220 ASP   X N   1 
ATOM   1710 C  CA  . ASP   A 1 234 ? 18.190  -5.017  10.291  1.00 34.02  ? 220 ASP   X CA  1 
ATOM   1711 C  C   . ASP   A 1 234 ? 17.633  -6.445  10.272  1.00 34.30  ? 220 ASP   X C   1 
ATOM   1712 O  O   . ASP   A 1 234 ? 16.993  -6.829  11.293  1.00 34.69  ? 220 ASP   X O   1 
ATOM   1713 C  CB  . ASP   A 1 234 ? 17.117  -4.029  10.703  1.00 33.97  ? 220 ASP   X CB  1 
ATOM   1714 C  CG  . ASP   A 1 234 ? 17.672  -2.654  11.121  1.00 37.35  ? 220 ASP   X CG  1 
ATOM   1715 O  OD1 . ASP   A 1 234 ? 18.905  -2.520  11.205  1.00 38.11  ? 220 ASP   X OD1 1 
ATOM   1716 O  OD2 . ASP   A 1 234 ? 16.887  -1.756  11.303  1.00 42.29  ? 220 ASP   X OD2 1 
ATOM   1717 N  N   . ALA   A 1 235 ? 17.899  -7.247  9.249   1.00 35.43  ? 221 ALA   X N   1 
ATOM   1718 C  CA  . ALA   A 1 235 ? 17.698  -8.717  9.334   1.00 33.90  ? 221 ALA   X CA  1 
ATOM   1719 C  C   . ALA   A 1 235 ? 18.559  -9.247  10.495  1.00 36.90  ? 221 ALA   X C   1 
ATOM   1720 O  O   . ALA   A 1 235 ? 18.160  -10.249 11.146  1.00 34.00  ? 221 ALA   X O   1 
ATOM   1721 C  CB  . ALA   A 1 235 ? 18.041  -9.404  8.032   1.00 32.28  ? 221 ALA   X CB  1 
ATOM   1722 N  N   . ILE   A 1 236 ? 19.705  -8.598  10.761  1.00 33.26  ? 222 ILE   X N   1 
ATOM   1723 C  CA  . ILE   A 1 236 ? 20.616  -8.980  11.879  1.00 33.82  ? 222 ILE   X CA  1 
ATOM   1724 C  C   . ILE   A 1 236 ? 21.228  -7.705  12.479  1.00 37.30  ? 222 ILE   X C   1 
ATOM   1725 O  O   . ILE   A 1 236 ? 22.162  -7.113  11.893  1.00 32.09  ? 222 ILE   X O   1 
ATOM   1726 C  CB  . ILE   A 1 236 ? 21.727  -9.964  11.453  1.00 38.12  ? 222 ILE   X CB  1 
ATOM   1727 C  CG1 . ILE   A 1 236 ? 21.213  -11.092 10.551  1.00 36.37  ? 222 ILE   X CG1 1 
ATOM   1728 C  CG2 . ILE   A 1 236 ? 22.451  -10.504 12.691  1.00 40.17  ? 222 ILE   X CG2 1 
ATOM   1729 C  CD1 . ILE   A 1 236 ? 22.338  -11.948 9.923   1.00 35.71  ? 222 ILE   X CD1 1 
ATOM   1730 N  N   . TYR   A 1 237 ? 20.785  -7.324  13.662  1.00 35.57  ? 223 TYR   X N   1 
ATOM   1731 C  CA  . TYR   A 1 237 ? 21.253  -6.067  14.290  1.00 38.42  ? 223 TYR   X CA  1 
ATOM   1732 C  C   . TYR   A 1 237 ? 22.765  -6.136  14.587  1.00 38.32  ? 223 TYR   X C   1 
ATOM   1733 O  O   . TYR   A 1 237 ? 23.474  -5.159  14.263  1.00 37.30  ? 223 TYR   X O   1 
ATOM   1734 C  CB  . TYR   A 1 237 ? 20.444  -5.844  15.565  1.00 38.63  ? 223 TYR   X CB  1 
ATOM   1735 C  CG  . TYR   A 1 237 ? 19.149  -5.089  15.477  1.00 33.88  ? 223 TYR   X CG  1 
ATOM   1736 C  CD1 . TYR   A 1 237 ? 18.904  -4.157  14.499  1.00 35.34  ? 223 TYR   X CD1 1 
ATOM   1737 C  CD2 . TYR   A 1 237 ? 18.230  -5.192  16.514  1.00 35.39  ? 223 TYR   X CD2 1 
ATOM   1738 C  CE1 . TYR   A 1 237 ? 17.749  -3.382  14.491  1.00 36.10  ? 223 TYR   X CE1 1 
ATOM   1739 C  CE2 . TYR   A 1 237 ? 17.071  -4.420  16.538  1.00 36.86  ? 223 TYR   X CE2 1 
ATOM   1740 C  CZ  . TYR   A 1 237 ? 16.846  -3.494  15.537  1.00 35.62  ? 223 TYR   X CZ  1 
ATOM   1741 O  OH  . TYR   A 1 237 ? 15.733  -2.728  15.572  1.00 34.95  ? 223 TYR   X OH  1 
ATOM   1742 N  N   . THR   A 1 238 ? 23.229  -7.204  15.264  1.00 33.58  ? 224 THR   X N   1 
ATOM   1743 C  CA  . THR   A 1 238 ? 24.594  -7.315  15.838  1.00 39.06  ? 224 THR   X CA  1 
ATOM   1744 C  C   . THR   A 1 238 ? 25.064  -8.768  15.841  1.00 38.04  ? 224 THR   X C   1 
ATOM   1745 O  O   . THR   A 1 238 ? 24.252  -9.666  15.649  1.00 36.71  ? 224 THR   X O   1 
ATOM   1746 C  CB  . THR   A 1 238 ? 24.665  -6.810  17.298  1.00 40.21  ? 224 THR   X CB  1 
ATOM   1747 O  OG1 . THR   A 1 238 ? 24.003  -7.738  18.168  1.00 40.48  ? 224 THR   X OG1 1 
ATOM   1748 C  CG2 . THR   A 1 238 ? 24.047  -5.448  17.483  1.00 40.36  ? 224 THR   X CG2 1 
ATOM   1749 N  N   . ALA   A 1 239 ? 26.328  -8.984  16.206  1.00 36.32  ? 225 ALA   X N   1 
ATOM   1750 C  CA  . ALA   A 1 239 ? 26.934  -10.324 16.385  1.00 41.17  ? 225 ALA   X CA  1 
ATOM   1751 C  C   . ALA   A 1 239 ? 26.182  -11.061 17.501  1.00 38.67  ? 225 ALA   X C   1 
ATOM   1752 O  O   . ALA   A 1 239 ? 26.055  -12.310 17.427  1.00 39.73  ? 225 ALA   X O   1 
ATOM   1753 C  CB  . ALA   A 1 239 ? 28.440  -10.218 16.625  1.00 39.55  ? 225 ALA   X CB  1 
ATOM   1754 N  N   . GLU   A 1 240 ? 25.678  -10.332 18.481  1.00 38.85  ? 226 GLU   X N   1 
ATOM   1755 C  CA  . GLU   A 1 240 ? 24.923  -10.926 19.609  1.00 42.45  ? 226 GLU   X CA  1 
ATOM   1756 C  C   . GLU   A 1 240 ? 23.592  -11.516 19.063  1.00 41.24  ? 226 GLU   X C   1 
ATOM   1757 O  O   . GLU   A 1 240 ? 23.220  -12.665 19.437  1.00 39.17  ? 226 GLU   X O   1 
ATOM   1758 C  CB  . GLU   A 1 240 ? 24.736  -9.856  20.691  1.00 44.66  ? 226 GLU   X CB  1 
ATOM   1759 C  CG  . GLU   A 1 240 ? 24.151  -10.440 21.975  1.00 50.19  ? 226 GLU   X CG  1 
ATOM   1760 C  CD  . GLU   A 1 240 ? 23.794  -9.477  23.102  1.00 56.19  ? 226 GLU   X CD  1 
ATOM   1761 O  OE1 . GLU   A 1 240 ? 24.099  -8.270  23.006  1.00 49.48  ? 226 GLU   X OE1 1 
ATOM   1762 O  OE2 . GLU   A 1 240 ? 23.192  -9.951  24.077  1.00 55.61  ? 226 GLU   X OE2 1 
ATOM   1763 N  N   . SER   A 1 241 ? 22.900  -10.763 18.186  1.00 39.31  ? 227 SER   X N   1 
ATOM   1764 C  CA  . SER   A 1 241 ? 21.690  -11.224 17.443  1.00 39.96  ? 227 SER   X CA  1 
ATOM   1765 C  C   . SER   A 1 241 ? 22.008  -12.543 16.732  1.00 38.12  ? 227 SER   X C   1 
ATOM   1766 O  O   . SER   A 1 241 ? 21.205  -13.519 16.823  1.00 36.52  ? 227 SER   X O   1 
ATOM   1767 C  CB  . SER   A 1 241 ? 21.195  -10.172 16.447  1.00 36.71  ? 227 SER   X CB  1 
ATOM   1768 O  OG  . SER   A 1 241 ? 21.142  -8.874  17.036  1.00 32.98  ? 227 SER   X OG  1 
ATOM   1769 N  N   . TYR   A 1 242 ? 23.132  -12.560 16.036  1.00 33.01  ? 228 TYR   X N   1 
ATOM   1770 C  CA  . TYR   A 1 242 ? 23.548  -13.614 15.091  1.00 37.08  ? 228 TYR   X CA  1 
ATOM   1771 C  C   . TYR   A 1 242 ? 23.897  -14.901 15.837  1.00 35.74  ? 228 TYR   X C   1 
ATOM   1772 O  O   . TYR   A 1 242 ? 23.550  -15.965 15.311  1.00 37.68  ? 228 TYR   X O   1 
ATOM   1773 C  CB  . TYR   A 1 242 ? 24.764  -13.150 14.304  1.00 36.92  ? 228 TYR   X CB  1 
ATOM   1774 C  CG  . TYR   A 1 242 ? 25.085  -13.928 13.062  1.00 39.11  ? 228 TYR   X CG  1 
ATOM   1775 C  CD1 . TYR   A 1 242 ? 24.120  -14.192 12.110  1.00 41.63  ? 228 TYR   X CD1 1 
ATOM   1776 C  CD2 . TYR   A 1 242 ? 26.382  -14.363 12.803  1.00 39.17  ? 228 TYR   X CD2 1 
ATOM   1777 C  CE1 . TYR   A 1 242 ? 24.426  -14.862 10.938  1.00 40.85  ? 228 TYR   X CE1 1 
ATOM   1778 C  CE2 . TYR   A 1 242 ? 26.710  -14.983 11.611  1.00 39.51  ? 228 TYR   X CE2 1 
ATOM   1779 C  CZ  . TYR   A 1 242 ? 25.730  -15.236 10.675  1.00 43.09  ? 228 TYR   X CZ  1 
ATOM   1780 O  OH  . TYR   A 1 242 ? 26.040  -15.851 9.504   1.00 39.95  ? 228 TYR   X OH  1 
ATOM   1781 N  N   . GLY   A 1 243 ? 24.511  -14.805 17.023  1.00 37.31  ? 229 GLY   X N   1 
ATOM   1782 C  CA  . GLY   A 1 243 ? 24.948  -16.001 17.784  1.00 41.99  ? 229 GLY   X CA  1 
ATOM   1783 C  C   . GLY   A 1 243 ? 25.773  -16.939 16.900  1.00 41.86  ? 229 GLY   X C   1 
ATOM   1784 O  O   . GLY   A 1 243 ? 26.685  -16.479 16.192  1.00 44.35  ? 229 GLY   X O   1 
ATOM   1785 N  N   . PRO   A 1 244 ? 25.509  -18.268 16.855  1.00 43.14  ? 230 PRO   X N   1 
ATOM   1786 C  CA  . PRO   A 1 244 ? 24.344  -18.894 17.480  1.00 51.09  ? 230 PRO   X CA  1 
ATOM   1787 C  C   . PRO   A 1 244 ? 24.485  -19.075 18.987  1.00 50.41  ? 230 PRO   X C   1 
ATOM   1788 O  O   . PRO   A 1 244 ? 25.591  -19.073 19.507  1.00 53.23  ? 230 PRO   X O   1 
ATOM   1789 C  CB  . PRO   A 1 244 ? 24.244  -20.275 16.820  1.00 50.69  ? 230 PRO   X CB  1 
ATOM   1790 C  CG  . PRO   A 1 244 ? 25.640  -20.573 16.297  1.00 55.29  ? 230 PRO   X CG  1 
ATOM   1791 C  CD  . PRO   A 1 244 ? 26.374  -19.247 16.178  1.00 47.96  ? 230 PRO   X CD  1 
ATOM   1792 N  N   . PRO   A 1 245 ? 23.386  -19.221 19.746  1.00 47.79  ? 231 PRO   X N   1 
ATOM   1793 C  CA  . PRO   A 1 245 ? 22.040  -19.231 19.190  1.00 48.07  ? 231 PRO   X CA  1 
ATOM   1794 C  C   . PRO   A 1 245 ? 21.533  -17.802 18.900  1.00 46.02  ? 231 PRO   X C   1 
ATOM   1795 O  O   . PRO   A 1 245 ? 22.105  -16.824 19.339  1.00 43.16  ? 231 PRO   X O   1 
ATOM   1796 C  CB  . PRO   A 1 245 ? 21.262  -19.916 20.324  1.00 50.74  ? 231 PRO   X CB  1 
ATOM   1797 C  CG  . PRO   A 1 245 ? 21.914  -19.335 21.578  1.00 58.02  ? 231 PRO   X CG  1 
ATOM   1798 C  CD  . PRO   A 1 245 ? 23.386  -19.288 21.220  1.00 57.40  ? 231 PRO   X CD  1 
ATOM   1799 N  N   . ILE   A 1 246 ? 20.429  -17.696 18.165  1.00 45.71  ? 232 ILE   X N   1 
ATOM   1800 C  CA  . ILE   A 1 246 ? 19.897  -16.377 17.716  1.00 39.04  ? 232 ILE   X CA  1 
ATOM   1801 C  C   . ILE   A 1 246 ? 19.312  -15.659 18.924  1.00 40.96  ? 232 ILE   X C   1 
ATOM   1802 O  O   . ILE   A 1 246 ? 18.615  -16.298 19.691  1.00 47.58  ? 232 ILE   X O   1 
ATOM   1803 C  CB  . ILE   A 1 246 ? 18.873  -16.578 16.596  1.00 39.91  ? 232 ILE   X CB  1 
ATOM   1804 C  CG1 . ILE   A 1 246 ? 19.542  -17.210 15.374  1.00 37.43  ? 232 ILE   X CG1 1 
ATOM   1805 C  CG2 . ILE   A 1 246 ? 18.180  -15.255 16.297  1.00 41.48  ? 232 ILE   X CG2 1 
ATOM   1806 C  CD1 . ILE   A 1 246 ? 18.586  -17.700 14.337  1.00 41.47  ? 232 ILE   X CD1 1 
ATOM   1807 N  N   . LYS   A 1 247 ? 19.582  -14.375 19.075  1.00 39.81  ? 233 LYS   X N   1 
ATOM   1808 C  CA  . LYS   A 1 247 ? 18.889  -13.511 20.057  1.00 39.28  ? 233 LYS   X CA  1 
ATOM   1809 C  C   . LYS   A 1 247 ? 18.050  -12.486 19.309  1.00 38.90  ? 233 LYS   X C   1 
ATOM   1810 O  O   . LYS   A 1 247 ? 18.553  -11.466 18.814  1.00 40.43  ? 233 LYS   X O   1 
ATOM   1811 C  CB  . LYS   A 1 247 ? 19.923  -12.893 20.998  1.00 41.39  ? 233 LYS   X CB  1 
ATOM   1812 C  CG  . LYS   A 1 247 ? 20.715  -13.911 21.816  1.00 45.01  ? 233 LYS   X CG  1 
ATOM   1813 C  CD  . LYS   A 1 247 ? 21.148  -13.352 23.184  1.00 56.55  ? 233 LYS   X CD  1 
ATOM   1814 C  CE  . LYS   A 1 247 ? 22.348  -14.037 23.810  1.00 66.80  ? 233 LYS   X CE  1 
ATOM   1815 N  NZ  . LYS   A 1 247 ? 22.972  -13.178 24.850  1.00 66.54  ? 233 LYS   X NZ  1 
ATOM   1816 N  N   . PRO   A 1 248 ? 16.731  -12.707 19.211  1.00 36.36  ? 234 PRO   X N   1 
ATOM   1817 C  CA  . PRO   A 1 248 ? 15.884  -11.789 18.472  1.00 39.74  ? 234 PRO   X CA  1 
ATOM   1818 C  C   . PRO   A 1 248 ? 15.656  -10.449 19.153  1.00 38.24  ? 234 PRO   X C   1 
ATOM   1819 O  O   . PRO   A 1 248 ? 15.879  -10.306 20.352  1.00 40.70  ? 234 PRO   X O   1 
ATOM   1820 C  CB  . PRO   A 1 248 ? 14.536  -12.540 18.347  1.00 40.27  ? 234 PRO   X CB  1 
ATOM   1821 C  CG  . PRO   A 1 248 ? 14.538  -13.481 19.524  1.00 44.94  ? 234 PRO   X CG  1 
ATOM   1822 C  CD  . PRO   A 1 248 ? 15.983  -13.869 19.754  1.00 41.37  ? 234 PRO   X CD  1 
ATOM   1823 N  N   . PRO   A 1 249 ? 15.262  -9.434  18.364  1.00 37.93  ? 235 PRO   X N   1 
ATOM   1824 C  CA  . PRO   A 1 249 ? 14.960  -8.099  18.875  1.00 39.62  ? 235 PRO   X CA  1 
ATOM   1825 C  C   . PRO   A 1 249 ? 13.637  -8.009  19.657  1.00 46.87  ? 235 PRO   X C   1 
ATOM   1826 O  O   . PRO   A 1 249 ? 12.811  -8.945  19.606  1.00 41.03  ? 235 PRO   X O   1 
ATOM   1827 C  CB  . PRO   A 1 249 ? 14.956  -7.236  17.598  1.00 43.45  ? 235 PRO   X CB  1 
ATOM   1828 C  CG  . PRO   A 1 249 ? 14.562  -8.196  16.495  1.00 41.46  ? 235 PRO   X CG  1 
ATOM   1829 C  CD  . PRO   A 1 249 ? 15.189  -9.510  16.894  1.00 39.88  ? 235 PRO   X CD  1 
ATOM   1830 N  N   . GLY   A 1 250 ? 13.483  -6.914  20.422  1.00 41.15  ? 236 GLY   X N   1 
ATOM   1831 C  CA  . GLY   A 1 250 ? 12.438  -6.808  21.467  1.00 46.45  ? 236 GLY   X CA  1 
ATOM   1832 C  C   . GLY   A 1 250 ? 11.052  -6.650  20.870  1.00 52.31  ? 236 GLY   X C   1 
ATOM   1833 O  O   . GLY   A 1 250 ? 10.028  -6.879  21.573  1.00 50.45  ? 236 GLY   X O   1 
ATOM   1834 N  N   . ILE   A 1 251 ? 11.002  -6.148  19.644  1.00 50.29  ? 237 ILE   X N   1 
ATOM   1835 C  CA  . ILE   A 1 251 ? 9.747   -6.063  18.873  1.00 56.53  ? 237 ILE   X CA  1 
ATOM   1836 C  C   . ILE   A 1 251 ? 10.074  -6.591  17.470  1.00 61.51  ? 237 ILE   X C   1 
ATOM   1837 O  O   . ILE   A 1 251 ? 11.224  -6.454  16.978  1.00 53.79  ? 237 ILE   X O   1 
ATOM   1838 C  CB  . ILE   A 1 251 ? 9.189   -4.622  18.914  1.00 64.24  ? 237 ILE   X CB  1 
ATOM   1839 C  CG1 . ILE   A 1 251 ? 7.671   -4.585  18.663  1.00 68.53  ? 237 ILE   X CG1 1 
ATOM   1840 C  CG2 . ILE   A 1 251 ? 9.999   -3.698  17.994  1.00 60.73  ? 237 ILE   X CG2 1 
ATOM   1841 C  CD1 . ILE   A 1 251 ? 7.248   -4.279  17.225  1.00 72.91  ? 237 ILE   X CD1 1 
ATOM   1842 N  N   . ILE   A 1 252 ? 9.093   -7.202  16.835  1.00 56.87  ? 238 ILE   X N   1 
ATOM   1843 C  CA  . ILE   A 1 252 ? 9.353   -7.920  15.570  1.00 53.87  ? 238 ILE   X CA  1 
ATOM   1844 C  C   . ILE   A 1 252 ? 8.035   -7.901  14.804  1.00 51.25  ? 238 ILE   X C   1 
ATOM   1845 O  O   . ILE   A 1 252 ? 7.011   -8.095  15.447  1.00 56.12  ? 238 ILE   X O   1 
ATOM   1846 C  CB  . ILE   A 1 252 ? 9.839   -9.320  15.995  1.00 54.07  ? 238 ILE   X CB  1 
ATOM   1847 C  CG1 . ILE   A 1 252 ? 10.747  -9.985  14.968  1.00 52.33  ? 238 ILE   X CG1 1 
ATOM   1848 C  CG2 . ILE   A 1 252 ? 8.670   -10.210 16.389  1.00 63.77  ? 238 ILE   X CG2 1 
ATOM   1849 C  CD1 . ILE   A 1 252 ? 11.677  -10.998 15.616  1.00 64.06  ? 238 ILE   X CD1 1 
ATOM   1850 N  N   . TYR   A 1 253 ? 8.035   -7.724  13.488  1.00 36.70  ? 239 TYR   X N   1 
ATOM   1851 C  CA  . TYR   A 1 253 ? 6.776   -7.923  12.748  1.00 38.09  ? 239 TYR   X CA  1 
ATOM   1852 C  C   . TYR   A 1 253 ? 6.471   -9.436  12.644  1.00 38.44  ? 239 TYR   X C   1 
ATOM   1853 O  O   . TYR   A 1 253 ? 5.367   -9.842  13.042  1.00 37.65  ? 239 TYR   X O   1 
ATOM   1854 C  CB  . TYR   A 1 253 ? 6.810   -7.257  11.375  1.00 34.90  ? 239 TYR   X CB  1 
ATOM   1855 C  CG  . TYR   A 1 253 ? 5.615   -7.630  10.557  1.00 32.20  ? 239 TYR   X CG  1 
ATOM   1856 C  CD1 . TYR   A 1 253 ? 4.335   -7.205  10.926  1.00 38.21  ? 239 TYR   X CD1 1 
ATOM   1857 C  CD2 . TYR   A 1 253 ? 5.752   -8.401  9.421   1.00 33.72  ? 239 TYR   X CD2 1 
ATOM   1858 C  CE1 . TYR   A 1 253 ? 3.213   -7.541  10.178  1.00 35.29  ? 239 TYR   X CE1 1 
ATOM   1859 C  CE2 . TYR   A 1 253 ? 4.644   -8.771  8.686   1.00 31.82  ? 239 TYR   X CE2 1 
ATOM   1860 C  CZ  . TYR   A 1 253 ? 3.386   -8.320  9.042   1.00 36.53  ? 239 TYR   X CZ  1 
ATOM   1861 O  OH  . TYR   A 1 253 ? 2.345   -8.715  8.259   1.00 38.25  ? 239 TYR   X OH  1 
ATOM   1862 N  N   . ASP   A 1 254 ? 7.372   -10.236 12.057  1.00 34.02  ? 240 ASP   X N   1 
ATOM   1863 C  CA  . ASP   A 1 254 ? 7.147   -11.673 11.764  1.00 33.40  ? 240 ASP   X CA  1 
ATOM   1864 C  C   . ASP   A 1 254 ? 8.248   -12.479 12.457  1.00 34.41  ? 240 ASP   X C   1 
ATOM   1865 O  O   . ASP   A 1 254 ? 9.346   -12.605 11.884  1.00 35.36  ? 240 ASP   X O   1 
ATOM   1866 C  CB  . ASP   A 1 254 ? 7.140   -11.860 10.243  1.00 34.18  ? 240 ASP   X CB  1 
ATOM   1867 C  CG  . ASP   A 1 254 ? 7.051   -13.295 9.757   1.00 34.85  ? 240 ASP   X CG  1 
ATOM   1868 O  OD1 . ASP   A 1 254 ? 6.773   -14.177 10.586  1.00 33.17  ? 240 ASP   X OD1 1 
ATOM   1869 O  OD2 . ASP   A 1 254 ? 7.308   -13.532 8.543   1.00 35.10  ? 240 ASP   X OD2 1 
ATOM   1870 N  N   . SER   A 1 255 ? 8.043   -12.944 13.676  1.00 34.36  ? 241 SER   X N   1 
ATOM   1871 C  CA  . SER   A 1 255 ? 9.102   -13.677 14.420  1.00 33.92  ? 241 SER   X CA  1 
ATOM   1872 C  C   . SER   A 1 255 ? 9.600   -14.887 13.613  1.00 31.69  ? 241 SER   X C   1 
ATOM   1873 O  O   . SER   A 1 255 ? 10.811  -15.105 13.603  1.00 34.41  ? 241 SER   X O   1 
ATOM   1874 C  CB  . SER   A 1 255 ? 8.643   -14.110 15.793  1.00 37.84  ? 241 SER   X CB  1 
ATOM   1875 O  OG  . SER   A 1 255 ? 7.470   -14.908 15.699  1.00 33.15  ? 241 SER   X OG  1 
ATOM   1876 N  N   . LEU   A 1 256 ? 8.724   -15.693 13.006  1.00 34.01  ? 242 LEU   X N   1 
ATOM   1877 C  CA  . LEU   A 1 256 ? 9.110   -16.931 12.285  1.00 33.06  ? 242 LEU   X CA  1 
ATOM   1878 C  C   . LEU   A 1 256 ? 9.984   -16.521 11.104  1.00 35.49  ? 242 LEU   X C   1 
ATOM   1879 O  O   . LEU   A 1 256 ? 11.039  -17.167 10.880  1.00 32.66  ? 242 LEU   X O   1 
ATOM   1880 C  CB  . LEU   A 1 256 ? 7.877   -17.722 11.823  1.00 35.59  ? 242 LEU   X CB  1 
ATOM   1881 C  CG  . LEU   A 1 256 ? 7.101   -18.442 12.939  1.00 39.68  ? 242 LEU   X CG  1 
ATOM   1882 C  CD1 . LEU   A 1 256 ? 5.981   -19.321 12.354  1.00 38.58  ? 242 LEU   X CD1 1 
ATOM   1883 C  CD2 . LEU   A 1 256 ? 8.016   -19.312 13.807  1.00 40.25  ? 242 LEU   X CD2 1 
ATOM   1884 N  N   . GLY   A 1 257 ? 9.554   -15.499 10.355  1.00 31.92  ? 243 GLY   X N   1 
ATOM   1885 C  CA  . GLY   A 1 257 ? 10.322  -15.030 9.185   1.00 32.66  ? 243 GLY   X CA  1 
ATOM   1886 C  C   . GLY   A 1 257 ? 11.680  -14.478 9.601   1.00 31.44  ? 243 GLY   X C   1 
ATOM   1887 O  O   . GLY   A 1 257 ? 12.674  -14.702 8.892   1.00 33.05  ? 243 GLY   X O   1 
ATOM   1888 N  N   . TYR   A 1 258 ? 11.729  -13.793 10.723  1.00 31.84  ? 244 TYR   X N   1 
ATOM   1889 C  CA  . TYR   A 1 258 ? 12.988  -13.249 11.280  1.00 35.32  ? 244 TYR   X CA  1 
ATOM   1890 C  C   . TYR   A 1 258 ? 13.966  -14.413 11.498  1.00 35.05  ? 244 TYR   X C   1 
ATOM   1891 O  O   . TYR   A 1 258 ? 15.086  -14.388 10.995  1.00 34.06  ? 244 TYR   X O   1 
ATOM   1892 C  CB  . TYR   A 1 258 ? 12.742  -12.466 12.576  1.00 34.34  ? 244 TYR   X CB  1 
ATOM   1893 C  CG  . TYR   A 1 258 ? 14.030  -12.044 13.231  1.00 34.02  ? 244 TYR   X CG  1 
ATOM   1894 C  CD1 . TYR   A 1 258 ? 14.673  -10.864 12.867  1.00 33.58  ? 244 TYR   X CD1 1 
ATOM   1895 C  CD2 . TYR   A 1 258 ? 14.648  -12.871 14.145  1.00 33.16  ? 244 TYR   X CD2 1 
ATOM   1896 C  CE1 . TYR   A 1 258 ? 15.905  -10.516 13.398  1.00 32.53  ? 244 TYR   X CE1 1 
ATOM   1897 C  CE2 . TYR   A 1 258 ? 15.871  -12.524 14.693  1.00 34.44  ? 244 TYR   X CE2 1 
ATOM   1898 C  CZ  . TYR   A 1 258 ? 16.496  -11.345 14.327  1.00 34.60  ? 244 TYR   X CZ  1 
ATOM   1899 O  OH  . TYR   A 1 258 ? 17.703  -11.053 14.875  1.00 36.21  ? 244 TYR   X OH  1 
ATOM   1900 N  N   . MET   A 1 259 ? 13.534  -15.425 12.247  1.00 32.63  ? 245 MET   X N   1 
ATOM   1901 C  CA  . MET   A 1 259 ? 14.399  -16.585 12.628  1.00 33.33  ? 245 MET   X CA  1 
ATOM   1902 C  C   . MET   A 1 259 ? 14.827  -17.320 11.353  1.00 35.94  ? 245 MET   X C   1 
ATOM   1903 O  O   . MET   A 1 259 ? 16.016  -17.674 11.261  1.00 36.77  ? 245 MET   X O   1 
ATOM   1904 C  CB  . MET   A 1 259 ? 13.655  -17.566 13.549  1.00 35.87  ? 245 MET   X CB  1 
ATOM   1905 C  CG  . MET   A 1 259 ? 13.218  -16.968 14.870  1.00 39.20  ? 245 MET   X CG  1 
ATOM   1906 S  SD  . MET   A 1 259 ? 14.601  -16.320 15.848  1.00 42.62  ? 245 MET   X SD  1 
ATOM   1907 C  CE  . MET   A 1 259 ? 15.332  -17.883 16.330  1.00 50.88  ? 245 MET   X CE  1 
ATOM   1908 N  N   . ASN   A 1 260 ? 13.901  -17.599 10.420  1.00 32.83  ? 246 ASN   X N   1 
ATOM   1909 C  CA  . ASN   A 1 260 ? 14.267  -18.243 9.137   1.00 34.61  ? 246 ASN   X CA  1 
ATOM   1910 C  C   . ASN   A 1 260 ? 15.293  -17.380 8.387   1.00 36.64  ? 246 ASN   X C   1 
ATOM   1911 O  O   . ASN   A 1 260 ? 16.228  -17.979 7.806   1.00 33.14  ? 246 ASN   X O   1 
ATOM   1912 C  CB  . ASN   A 1 260 ? 13.071  -18.532 8.231   1.00 39.53  ? 246 ASN   X CB  1 
ATOM   1913 C  CG  . ASN   A 1 260 ? 12.124  -19.540 8.854   1.00 43.83  ? 246 ASN   X CG  1 
ATOM   1914 O  OD1 . ASN   A 1 260 ? 12.513  -20.330 9.693   1.00 39.94  ? 246 ASN   X OD1 1 
ATOM   1915 N  ND2 . ASN   A 1 260 ? 10.864  -19.472 8.501   1.00 48.50  ? 246 ASN   X ND2 1 
ATOM   1916 N  N   . THR   A 1 261 ? 15.116  -16.061 8.367   1.00 33.07  ? 247 THR   X N   1 
ATOM   1917 C  CA  . THR   A 1 261 ? 16.015  -15.135 7.615   1.00 33.33  ? 247 THR   X CA  1 
ATOM   1918 C  C   . THR   A 1 261 ? 17.429  -15.251 8.187   1.00 34.65  ? 247 THR   X C   1 
ATOM   1919 O  O   . THR   A 1 261 ? 18.403  -15.333 7.378   1.00 33.17  ? 247 THR   X O   1 
ATOM   1920 C  CB  . THR   A 1 261 ? 15.493  -13.693 7.595   1.00 33.72  ? 247 THR   X CB  1 
ATOM   1921 O  OG1 . THR   A 1 261 ? 14.325  -13.735 6.780   1.00 32.29  ? 247 THR   X OG1 1 
ATOM   1922 C  CG2 . THR   A 1 261 ? 16.475  -12.689 7.016   1.00 34.57  ? 247 THR   X CG2 1 
ATOM   1923 N  N   . VAL   A 1 262 ? 17.580  -15.252 9.512   1.00 33.03  ? 248 VAL   X N   1 
ATOM   1924 C  CA  . VAL   A 1 262 ? 18.954  -15.278 10.100  1.00 33.68  ? 248 VAL   X CA  1 
ATOM   1925 C  C   . VAL   A 1 262 ? 19.667  -16.567 9.693   1.00 36.04  ? 248 VAL   X C   1 
ATOM   1926 O  O   . VAL   A 1 262 ? 20.831  -16.486 9.292   1.00 32.27  ? 248 VAL   X O   1 
ATOM   1927 C  CB  . VAL   A 1 262 ? 18.954  -15.081 11.623  1.00 32.61  ? 248 VAL   X CB  1 
ATOM   1928 C  CG1 . VAL   A 1 262 ? 20.375  -15.120 12.156  1.00 35.53  ? 248 VAL   X CG1 1 
ATOM   1929 C  CG2 . VAL   A 1 262 ? 18.276  -13.770 12.036  1.00 34.58  ? 248 VAL   X CG2 1 
ATOM   1930 N  N   . GLU   A 1 263 ? 18.970  -17.708 9.723   1.00 34.70  ? 249 GLU   X N   1 
ATOM   1931 C  CA  . GLU   A 1 263 ? 19.567  -19.028 9.410   1.00 36.23  ? 249 GLU   X CA  1 
ATOM   1932 C  C   . GLU   A 1 263 ? 19.860  -19.091 7.914   1.00 36.33  ? 249 GLU   X C   1 
ATOM   1933 O  O   . GLU   A 1 263 ? 20.844  -19.724 7.510   1.00 37.83  ? 249 GLU   X O   1 
ATOM   1934 C  CB  . GLU   A 1 263 ? 18.643  -20.159 9.903   1.00 40.47  ? 249 GLU   X CB  1 
ATOM   1935 C  CG  . GLU   A 1 263 ? 18.705  -20.396 11.411  1.00 45.72  ? 249 GLU   X CG  1 
ATOM   1936 C  CD  . GLU   A 1 263 ? 20.130  -20.493 11.994  1.00 53.56  ? 249 GLU   X CD  1 
ATOM   1937 O  OE1 . GLU   A 1 263 ? 21.072  -20.984 11.289  1.00 50.30  ? 249 GLU   X OE1 1 
ATOM   1938 O  OE2 . GLU   A 1 263 ? 20.319  -20.078 13.149  1.00 58.44  ? 249 GLU   X OE2 1 
ATOM   1939 N  N   . ARG   A 1 264 ? 19.026  -18.462 7.091   1.00 35.99  ? 250 ARG   X N   1 
ATOM   1940 C  CA  . ARG   A 1 264 ? 19.255  -18.420 5.630   1.00 34.35  ? 250 ARG   X CA  1 
ATOM   1941 C  C   . ARG   A 1 264 ? 20.543  -17.630 5.352   1.00 32.18  ? 250 ARG   X C   1 
ATOM   1942 O  O   . ARG   A 1 264 ? 21.362  -18.080 4.536   1.00 33.06  ? 250 ARG   X O   1 
ATOM   1943 C  CB  . ARG   A 1 264 ? 18.070  -17.769 4.918   1.00 37.00  ? 250 ARG   X CB  1 
ATOM   1944 C  CG  . ARG   A 1 264 ? 18.273  -17.590 3.418   1.00 36.40  ? 250 ARG   X CG  1 
ATOM   1945 C  CD  . ARG   A 1 264 ? 17.065  -16.940 2.799   1.00 39.47  ? 250 ARG   X CD  1 
ATOM   1946 N  NE  . ARG   A 1 264 ? 17.394  -16.560 1.454   1.00 41.15  ? 250 ARG   X NE  1 
ATOM   1947 C  CZ  . ARG   A 1 264 ? 16.711  -15.704 0.706   1.00 41.25  ? 250 ARG   X CZ  1 
ATOM   1948 N  NH1 . ARG   A 1 264 ? 15.624  -15.114 1.168   1.00 38.09  ? 250 ARG   X NH1 1 
ATOM   1949 N  NH2 . ARG   A 1 264 ? 17.147  -15.455 -0.507  1.00 42.26  ? 250 ARG   X NH2 1 
ATOM   1950 N  N   . ILE   A 1 265 ? 20.698  -16.485 5.996   1.00 31.61  ? 251 ILE   X N   1 
ATOM   1951 C  CA  . ILE   A 1 265 ? 21.922  -15.658 5.861   1.00 31.72  ? 251 ILE   X CA  1 
ATOM   1952 C  C   . ILE   A 1 265 ? 23.156  -16.483 6.298   1.00 31.32  ? 251 ILE   X C   1 
ATOM   1953 O  O   . ILE   A 1 265 ? 24.164  -16.448 5.569   1.00 33.87  ? 251 ILE   X O   1 
ATOM   1954 C  CB  . ILE   A 1 265 ? 21.773  -14.330 6.616   1.00 32.52  ? 251 ILE   X CB  1 
ATOM   1955 C  CG1 . ILE   A 1 265 ? 20.723  -13.425 5.951   1.00 31.84  ? 251 ILE   X CG1 1 
ATOM   1956 C  CG2 . ILE   A 1 265 ? 23.145  -13.632 6.732   1.00 35.64  ? 251 ILE   X CG2 1 
ATOM   1957 C  CD1 . ILE   A 1 265 ? 20.330  -12.258 6.783   1.00 33.77  ? 251 ILE   X CD1 1 
ATOM   1958 N  N   . ARG   A 1 266 ? 23.076  -17.171 7.438   1.00 37.43  ? 252 ARG   X N   1 
ATOM   1959 C  CA  . ARG   A 1 266 ? 24.149  -18.073 7.946   1.00 35.38  ? 252 ARG   X CA  1 
ATOM   1960 C  C   . ARG   A 1 266 ? 24.534  -19.103 6.884   1.00 40.36  ? 252 ARG   X C   1 
ATOM   1961 O  O   . ARG   A 1 266 ? 25.759  -19.263 6.661   1.00 35.63  ? 252 ARG   X O   1 
ATOM   1962 C  CB  . ARG   A 1 266 ? 23.771  -18.721 9.276   1.00 37.13  ? 252 ARG   X CB  1 
ATOM   1963 C  CG  . ARG   A 1 266 ? 24.981  -19.261 10.029  1.00 42.14  ? 252 ARG   X CG  1 
ATOM   1964 C  CD  . ARG   A 1 266 ? 24.619  -20.121 11.226  1.00 40.97  ? 252 ARG   X CD  1 
ATOM   1965 N  NE  . ARG   A 1 266 ? 23.539  -19.549 12.024  1.00 39.30  ? 252 ARG   X NE  1 
ATOM   1966 C  CZ  . ARG   A 1 266 ? 23.646  -18.521 12.870  1.00 39.97  ? 252 ARG   X CZ  1 
ATOM   1967 N  NH1 . ARG   A 1 266 ? 24.792  -17.876 13.031  1.00 37.91  ? 252 ARG   X NH1 1 
ATOM   1968 N  NH2 . ARG   A 1 266 ? 22.582  -18.147 13.572  1.00 43.81  ? 252 ARG   X NH2 1 
ATOM   1969 N  N   . ARG   A 1 267 ? 23.563  -19.730 6.204   1.00 36.13  ? 253 ARG   X N   1 
ATOM   1970 C  CA  . ARG   A 1 267 ? 23.848  -20.793 5.210   1.00 39.70  ? 253 ARG   X CA  1 
ATOM   1971 C  C   . ARG   A 1 267 ? 24.498  -20.155 3.956   1.00 38.75  ? 253 ARG   X C   1 
ATOM   1972 O  O   . ARG   A 1 267 ? 25.494  -20.680 3.411   1.00 36.46  ? 253 ARG   X O   1 
ATOM   1973 C  CB  . ARG   A 1 267 ? 22.583  -21.605 4.897   1.00 44.19  ? 253 ARG   X CB  1 
ATOM   1974 C  CG  . ARG   A 1 267 ? 22.645  -22.270 3.528   1.00 61.81  ? 253 ARG   X CG  1 
ATOM   1975 C  CD  . ARG   A 1 267 ? 21.375  -22.789 2.867   1.00 72.18  ? 253 ARG   X CD  1 
ATOM   1976 N  NE  . ARG   A 1 267 ? 20.352  -21.802 2.500   1.00 77.62  ? 253 ARG   X NE  1 
ATOM   1977 C  CZ  . ARG   A 1 267 ? 20.329  -21.046 1.393   1.00 71.85  ? 253 ARG   X CZ  1 
ATOM   1978 N  NH1 . ARG   A 1 267 ? 21.311  -21.081 0.509   1.00 66.74  ? 253 ARG   X NH1 1 
ATOM   1979 N  NH2 . ARG   A 1 267 ? 19.303  -20.239 1.182   1.00 70.87  ? 253 ARG   X NH2 1 
ATOM   1980 N  N   . ILE   A 1 268 ? 23.939  -19.067 3.455   1.00 35.84  ? 254 ILE   X N   1 
ATOM   1981 C  CA  . ILE   A 1 268 ? 24.523  -18.331 2.300   1.00 39.28  ? 254 ILE   X CA  1 
ATOM   1982 C  C   . ILE   A 1 268 ? 25.969  -17.938 2.615   1.00 36.69  ? 254 ILE   X C   1 
ATOM   1983 O  O   . ILE   A 1 268 ? 26.811  -18.167 1.756   1.00 38.27  ? 254 ILE   X O   1 
ATOM   1984 C  CB  . ILE   A 1 268 ? 23.695  -17.087 1.930   1.00 41.43  ? 254 ILE   X CB  1 
ATOM   1985 C  CG1 . ILE   A 1 268 ? 22.265  -17.463 1.499   1.00 45.50  ? 254 ILE   X CG1 1 
ATOM   1986 C  CG2 . ILE   A 1 268 ? 24.420  -16.299 0.846   1.00 39.19  ? 254 ILE   X CG2 1 
ATOM   1987 C  CD1 . ILE   A 1 268 ? 21.336  -16.263 1.349   1.00 41.12  ? 254 ILE   X CD1 1 
ATOM   1988 N  N   . ALA   A 1 269 ? 26.250  -17.369 3.791   1.00 35.36  ? 255 ALA   X N   1 
ATOM   1989 C  CA  . ALA   A 1 269 ? 27.615  -16.977 4.196   1.00 36.63  ? 255 ALA   X CA  1 
ATOM   1990 C  C   . ALA   A 1 269 ? 28.553  -18.199 4.142   1.00 37.65  ? 255 ALA   X C   1 
ATOM   1991 O  O   . ALA   A 1 269 ? 29.704  -18.053 3.657   1.00 35.68  ? 255 ALA   X O   1 
ATOM   1992 C  CB  . ALA   A 1 269 ? 27.623  -16.360 5.557   1.00 34.89  ? 255 ALA   X CB  1 
ATOM   1993 N  N   . GLN   A 1 270 ? 28.085  -19.345 4.629   1.00 39.66  ? 256 GLN   X N   1 
ATOM   1994 C  CA  . GLN   A 1 270 ? 28.845  -20.624 4.686   1.00 41.68  ? 256 GLN   X CA  1 
ATOM   1995 C  C   . GLN   A 1 270 ? 29.098  -21.146 3.268   1.00 39.49  ? 256 GLN   X C   1 
ATOM   1996 O  O   . GLN   A 1 270 ? 30.248  -21.449 2.941   1.00 42.67  ? 256 GLN   X O   1 
ATOM   1997 C  CB  . GLN   A 1 270 ? 28.111  -21.629 5.566   1.00 46.77  ? 256 GLN   X CB  1 
ATOM   1998 C  CG  . GLN   A 1 270 ? 28.893  -22.918 5.795   1.00 54.81  ? 256 GLN   X CG  1 
ATOM   1999 C  CD  . GLN   A 1 270 ? 28.076  -24.161 5.521   1.00 61.31  ? 256 GLN   X CD  1 
ATOM   2000 O  OE1 . GLN   A 1 270 ? 26.843  -24.142 5.455   1.00 62.05  ? 256 GLN   X OE1 1 
ATOM   2001 N  NE2 . GLN   A 1 270 ? 28.773  -25.265 5.341   1.00 64.20  ? 256 GLN   X NE2 1 
ATOM   2002 N  N   . GLU   A 1 271 ? 28.081  -21.200 2.423   1.00 40.78  ? 257 GLU   X N   1 
ATOM   2003 C  CA  . GLU   A 1 271 ? 28.138  -21.814 1.074   1.00 42.06  ? 257 GLU   X CA  1 
ATOM   2004 C  C   . GLU   A 1 271 ? 28.925  -20.901 0.123   1.00 45.26  ? 257 GLU   X C   1 
ATOM   2005 O  O   . GLU   A 1 271 ? 29.504  -21.428 -0.806  1.00 48.92  ? 257 GLU   X O   1 
ATOM   2006 C  CB  . GLU   A 1 271 ? 26.722  -22.095 0.550   1.00 45.03  ? 257 GLU   X CB  1 
ATOM   2007 C  CG  . GLU   A 1 271 ? 26.017  -23.245 1.280   1.00 47.25  ? 257 GLU   X CG  1 
ATOM   2008 C  CD  . GLU   A 1 271 ? 24.554  -23.500 0.903   1.00 54.31  ? 257 GLU   X CD  1 
ATOM   2009 O  OE1 . GLU   A 1 271 ? 24.012  -22.815 0.012   1.00 52.45  ? 257 GLU   X OE1 1 
ATOM   2010 O  OE2 . GLU   A 1 271 ? 23.942  -24.346 1.544   1.00 53.94  ? 257 GLU   X OE2 1 
ATOM   2011 N  N   . THR   A 1 272 ? 29.010  -19.590 0.366   1.00 42.93  ? 258 THR   X N   1 
ATOM   2012 C  CA  . THR   A 1 272 ? 29.654  -18.636 -0.572  1.00 45.05  ? 258 THR   X CA  1 
ATOM   2013 C  C   . THR   A 1 272 ? 30.931  -18.038 0.028   1.00 44.72  ? 258 THR   X C   1 
ATOM   2014 O  O   . THR   A 1 272 ? 31.549  -17.222 -0.652  1.00 44.03  ? 258 THR   X O   1 
ATOM   2015 C  CB  . THR   A 1 272 ? 28.651  -17.557 -1.012  1.00 45.55  ? 258 THR   X CB  1 
ATOM   2016 O  OG1 . THR   A 1 272 ? 28.421  -16.707 0.115   1.00 38.09  ? 258 THR   X OG1 1 
ATOM   2017 C  CG2 . THR   A 1 272 ? 27.357  -18.140 -1.562  1.00 42.55  ? 258 THR   X CG2 1 
ATOM   2018 N  N   . LYS   A 1 273 ? 31.315  -18.424 1.247   1.00 41.42  ? 259 LYS   X N   1 
ATOM   2019 C  CA  . LYS   A 1 273 ? 32.463  -17.848 2.022   1.00 42.43  ? 259 LYS   X CA  1 
ATOM   2020 C  C   . LYS   A 1 273 ? 32.362  -16.322 2.032   1.00 41.05  ? 259 LYS   X C   1 
ATOM   2021 O  O   . LYS   A 1 273 ? 33.355  -15.606 1.732   1.00 42.03  ? 259 LYS   X O   1 
ATOM   2022 C  CB  . LYS   A 1 273 ? 33.807  -18.375 1.505   1.00 51.33  ? 259 LYS   X CB  1 
ATOM   2023 C  CG  . LYS   A 1 273 ? 33.828  -19.850 1.097   1.00 64.04  ? 259 LYS   X CG  1 
ATOM   2024 C  CD  . LYS   A 1 273 ? 34.883  -20.138 0.017   1.00 78.24  ? 259 LYS   X CD  1 
ATOM   2025 C  CE  . LYS   A 1 273 ? 34.634  -21.384 -0.813  1.00 91.61  ? 259 LYS   X CE  1 
ATOM   2026 N  NZ  . LYS   A 1 273 ? 34.941  -22.613 -0.045  1.00 97.69  ? 259 LYS   X NZ  1 
ATOM   2027 N  N   . SER   A 1 274 ? 31.210  -15.810 2.450   1.00 37.18  ? 260 SER   X N   1 
ATOM   2028 C  CA  . SER   A 1 274 ? 30.943  -14.348 2.488   1.00 35.77  ? 260 SER   X CA  1 
ATOM   2029 C  C   . SER   A 1 274 ? 30.995  -13.882 3.938   1.00 37.07  ? 260 SER   X C   1 
ATOM   2030 O  O   . SER   A 1 274 ? 30.514  -14.593 4.808   1.00 37.88  ? 260 SER   X O   1 
ATOM   2031 C  CB  . SER   A 1 274 ? 29.641  -13.970 1.853   1.00 37.82  ? 260 SER   X CB  1 
ATOM   2032 O  OG  . SER   A 1 274 ? 29.607  -14.320 0.482   1.00 37.98  ? 260 SER   X OG  1 
ATOM   2033 N  N   . GLN   A 1 275 ? 31.474  -12.666 4.143   1.00 36.69  ? 261 GLN   X N   1 
ATOM   2034 C  CA  . GLN   A 1 275 ? 31.319  -11.905 5.408   1.00 38.79  ? 261 GLN   X CA  1 
ATOM   2035 C  C   . GLN   A 1 275 ? 29.867  -11.440 5.530   1.00 35.88  ? 261 GLN   X C   1 
ATOM   2036 O  O   . GLN   A 1 275 ? 29.203  -11.222 4.482   1.00 37.55  ? 261 GLN   X O   1 
ATOM   2037 C  CB  . GLN   A 1 275 ? 32.175  -10.635 5.396   1.00 39.45  ? 261 GLN   X CB  1 
ATOM   2038 C  CG  . GLN   A 1 275 ? 33.663  -10.859 5.303   1.00 42.77  ? 261 GLN   X CG  1 
ATOM   2039 C  CD  . GLN   A 1 275 ? 34.317  -9.504  5.122   1.00 48.80  ? 261 GLN   X CD  1 
ATOM   2040 O  OE1 . GLN   A 1 275 ? 34.101  -8.598  5.925   1.00 40.15  ? 261 GLN   X OE1 1 
ATOM   2041 N  NE2 . GLN   A 1 275 ? 35.101  -9.340  4.066   1.00 46.49  ? 261 GLN   X NE2 1 
ATOM   2042 N  N   . VAL   A 1 276 ? 29.375  -11.325 6.750   1.00 35.55  ? 262 VAL   X N   1 
ATOM   2043 C  CA  . VAL   A 1 276 ? 28.021  -10.809 7.028   1.00 35.79  ? 262 VAL   X CA  1 
ATOM   2044 C  C   . VAL   A 1 276 ? 28.208  -9.459  7.723   1.00 37.13  ? 262 VAL   X C   1 
ATOM   2045 O  O   . VAL   A 1 276 ? 28.737  -9.418  8.823   1.00 34.88  ? 262 VAL   X O   1 
ATOM   2046 C  CB  . VAL   A 1 276 ? 27.203  -11.809 7.847   1.00 37.09  ? 262 VAL   X CB  1 
ATOM   2047 C  CG1 . VAL   A 1 276 ? 25.856  -11.235 8.188   1.00 37.88  ? 262 VAL   X CG1 1 
ATOM   2048 C  CG2 . VAL   A 1 276 ? 27.070  -13.164 7.132   1.00 37.57  ? 262 VAL   X CG2 1 
ATOM   2049 N  N   . TRP   A 1 277 ? 27.720  -8.392  7.111   1.00 34.70  ? 263 TRP   X N   1 
ATOM   2050 C  CA  . TRP   A 1 277 ? 27.772  -7.035  7.707   1.00 34.93  ? 263 TRP   X CA  1 
ATOM   2051 C  C   . TRP   A 1 277 ? 26.400  -6.741  8.346   1.00 35.74  ? 263 TRP   X C   1 
ATOM   2052 O  O   . TRP   A 1 277 ? 25.390  -6.668  7.649   1.00 35.86  ? 263 TRP   X O   1 
ATOM   2053 C  CB  . TRP   A 1 277 ? 28.169  -6.021  6.654   1.00 34.33  ? 263 TRP   X CB  1 
ATOM   2054 C  CG  . TRP   A 1 277 ? 29.585  -6.124  6.194   1.00 39.96  ? 263 TRP   X CG  1 
ATOM   2055 C  CD1 . TRP   A 1 277 ? 30.478  -7.117  6.452   1.00 41.53  ? 263 TRP   X CD1 1 
ATOM   2056 C  CD2 . TRP   A 1 277 ? 30.281  -5.178  5.365   1.00 34.75  ? 263 TRP   X CD2 1 
ATOM   2057 N  NE1 . TRP   A 1 277 ? 31.686  -6.833  5.861   1.00 42.67  ? 263 TRP   X NE1 1 
ATOM   2058 C  CE2 . TRP   A 1 277 ? 31.582  -5.666  5.174   1.00 36.09  ? 263 TRP   X CE2 1 
ATOM   2059 C  CE3 . TRP   A 1 277 ? 29.930  -3.959  4.788   1.00 37.87  ? 263 TRP   X CE3 1 
ATOM   2060 C  CZ2 . TRP   A 1 277 ? 32.528  -4.981  4.416   1.00 40.37  ? 263 TRP   X CZ2 1 
ATOM   2061 C  CZ3 . TRP   A 1 277 ? 30.876  -3.266  4.074   1.00 36.96  ? 263 TRP   X CZ3 1 
ATOM   2062 C  CH2 . TRP   A 1 277 ? 32.152  -3.770  3.895   1.00 37.95  ? 263 TRP   X CH2 1 
ATOM   2063 N  N   . PHE   A 1 278 ? 26.395  -6.565  9.651   1.00 33.13  ? 264 PHE   X N   1 
ATOM   2064 C  CA  . PHE   A 1 278 ? 25.188  -6.396  10.498  1.00 33.99  ? 264 PHE   X CA  1 
ATOM   2065 C  C   . PHE   A 1 278 ? 24.696  -4.962  10.313  1.00 36.82  ? 264 PHE   X C   1 
ATOM   2066 O  O   . PHE   A 1 278 ? 25.461  -4.061  9.842   1.00 35.81  ? 264 PHE   X O   1 
ATOM   2067 C  CB  . PHE   A 1 278 ? 25.533  -6.799  11.938  1.00 32.54  ? 264 PHE   X CB  1 
ATOM   2068 C  CG  . PHE   A 1 278 ? 26.141  -8.179  12.090  1.00 36.18  ? 264 PHE   X CG  1 
ATOM   2069 C  CD1 . PHE   A 1 278 ? 25.525  -9.306  11.553  1.00 33.14  ? 264 PHE   X CD1 1 
ATOM   2070 C  CD2 . PHE   A 1 278 ? 27.343  -8.366  12.759  1.00 39.30  ? 264 PHE   X CD2 1 
ATOM   2071 C  CE1 . PHE   A 1 278 ? 26.033  -10.581 11.760  1.00 37.42  ? 264 PHE   X CE1 1 
ATOM   2072 C  CE2 . PHE   A 1 278 ? 27.901  -9.638  12.883  1.00 40.76  ? 264 PHE   X CE2 1 
ATOM   2073 C  CZ  . PHE   A 1 278 ? 27.227  -10.752 12.412  1.00 37.59  ? 264 PHE   X CZ  1 
ATOM   2074 N  N   . GLY   A 1 279 ? 23.433  -4.739  10.663  1.00 34.66  ? 265 GLY   X N   1 
ATOM   2075 C  CA  . GLY   A 1 279 ? 22.815  -3.401  10.575  1.00 36.53  ? 265 GLY   X CA  1 
ATOM   2076 C  C   . GLY   A 1 279 ? 23.480  -2.380  11.504  1.00 36.24  ? 265 GLY   X C   1 
ATOM   2077 O  O   . GLY   A 1 279 ? 23.668  -1.231  11.091  1.00 35.92  ? 265 GLY   X O   1 
ATOM   2078 N  N   . HIS   A 1 280 ? 23.776  -2.747  12.754  1.00 35.06  ? 266 HIS   X N   1 
ATOM   2079 C  CA  . HIS   A 1 280 ? 24.050  -1.737  13.812  1.00 36.02  ? 266 HIS   X CA  1 
ATOM   2080 C  C   . HIS   A 1 280 ? 25.011  -2.295  14.864  1.00 33.76  ? 266 HIS   X C   1 
ATOM   2081 O  O   . HIS   A 1 280 ? 24.727  -2.173  16.060  1.00 38.93  ? 266 HIS   X O   1 
ATOM   2082 C  CB  . HIS   A 1 280 ? 22.730  -1.266  14.444  1.00 35.31  ? 266 HIS   X CB  1 
ATOM   2083 C  CG  . HIS   A 1 280 ? 21.746  -0.587  13.551  1.00 37.58  ? 266 HIS   X CG  1 
ATOM   2084 N  ND1 . HIS   A 1 280 ? 22.051  0.572   12.823  1.00 32.24  ? 266 HIS   X ND1 1 
ATOM   2085 C  CD2 . HIS   A 1 280 ? 20.448  -0.888  13.289  1.00 35.78  ? 266 HIS   X CD2 1 
ATOM   2086 C  CE1 . HIS   A 1 280 ? 20.986  0.945   12.167  1.00 38.56  ? 266 HIS   X CE1 1 
ATOM   2087 N  NE2 . HIS   A 1 280 ? 19.972  0.067   12.458  1.00 32.60  ? 266 HIS   X NE2 1 
ATOM   2088 N  N   . ASP   A 1 281 ? 26.104  -2.920  14.439  1.00 36.71  ? 267 ASP   X N   1 
ATOM   2089 C  CA  . ASP   A 1 281 ? 27.076  -3.554  15.371  1.00 37.54  ? 267 ASP   X CA  1 
ATOM   2090 C  C   . ASP   A 1 281 ? 28.237  -2.560  15.592  1.00 37.91  ? 267 ASP   X C   1 
ATOM   2091 O  O   . ASP   A 1 281 ? 29.095  -2.447  14.722  1.00 38.90  ? 267 ASP   X O   1 
ATOM   2092 C  CB  . ASP   A 1 281 ? 27.517  -4.917  14.848  1.00 39.74  ? 267 ASP   X CB  1 
ATOM   2093 C  CG  . ASP   A 1 281 ? 28.364  -5.727  15.830  1.00 40.46  ? 267 ASP   X CG  1 
ATOM   2094 O  OD1 . ASP   A 1 281 ? 29.161  -5.123  16.573  1.00 45.30  ? 267 ASP   X OD1 1 
ATOM   2095 O  OD2 . ASP   A 1 281 ? 28.209  -6.939  15.827  1.00 48.07  ? 267 ASP   X OD2 1 
ATOM   2096 N  N   . ALA   A 1 282 ? 28.258  -1.860  16.724  1.00 38.34  ? 268 ALA   X N   1 
ATOM   2097 C  CA  . ALA   A 1 282 ? 29.338  -0.878  17.052  1.00 42.93  ? 268 ALA   X CA  1 
ATOM   2098 C  C   . ALA   A 1 282 ? 30.732  -1.528  16.902  1.00 39.86  ? 268 ALA   X C   1 
ATOM   2099 O  O   . ALA   A 1 282 ? 31.630  -0.867  16.349  1.00 42.08  ? 268 ALA   X O   1 
ATOM   2100 C  CB  . ALA   A 1 282 ? 29.133  -0.276  18.446  1.00 39.57  ? 268 ALA   X CB  1 
ATOM   2101 N  N   . GLU   A 1 283 ? 30.941  -2.746  17.391  1.00 38.97  ? 269 GLU   X N   1 
ATOM   2102 C  CA  . GLU   A 1 283 ? 32.300  -3.355  17.370  1.00 45.33  ? 269 GLU   X CA  1 
ATOM   2103 C  C   . GLU   A 1 283 ? 32.667  -3.702  15.926  1.00 47.81  ? 269 GLU   X C   1 
ATOM   2104 O  O   . GLU   A 1 283 ? 33.809  -3.428  15.533  1.00 40.43  ? 269 GLU   X O   1 
ATOM   2105 C  CB  . GLU   A 1 283 ? 32.412  -4.555  18.314  1.00 54.17  ? 269 GLU   X CB  1 
ATOM   2106 C  CG  . GLU   A 1 283 ? 32.177  -4.166  19.763  1.00 68.53  ? 269 GLU   X CG  1 
ATOM   2107 C  CD  . GLU   A 1 283 ? 32.400  -5.261  20.800  1.00 88.98  ? 269 GLU   X CD  1 
ATOM   2108 O  OE1 . GLU   A 1 283 ? 32.717  -6.415  20.404  1.00 103.94 ? 269 GLU   X OE1 1 
ATOM   2109 O  OE2 . GLU   A 1 283 ? 32.255  -4.959  22.015  1.00 102.92 ? 269 GLU   X OE2 1 
ATOM   2110 N  N   . GLN   A 1 284 ? 31.743  -4.269  15.131  1.00 41.95  ? 270 GLN   X N   1 
ATOM   2111 C  CA  . GLN   A 1 284 ? 32.064  -4.557  13.713  1.00 40.10  ? 270 GLN   X CA  1 
ATOM   2112 C  C   . GLN   A 1 284 ? 32.350  -3.257  12.933  1.00 37.74  ? 270 GLN   X C   1 
ATOM   2113 O  O   . GLN   A 1 284 ? 33.262  -3.241  12.026  1.00 39.62  ? 270 GLN   X O   1 
ATOM   2114 C  CB  . GLN   A 1 284 ? 30.934  -5.345  13.064  1.00 38.01  ? 270 GLN   X CB  1 
ATOM   2115 C  CG  . GLN   A 1 284 ? 31.229  -5.712  11.626  1.00 38.40  ? 270 GLN   X CG  1 
ATOM   2116 C  CD  . GLN   A 1 284 ? 30.046  -6.453  11.024  1.00 45.12  ? 270 GLN   X CD  1 
ATOM   2117 O  OE1 . GLN   A 1 284 ? 28.934  -5.926  10.925  1.00 40.15  ? 270 GLN   X OE1 1 
ATOM   2118 N  NE2 . GLN   A 1 284 ? 30.280  -7.690  10.607  1.00 38.05  ? 270 GLN   X NE2 1 
ATOM   2119 N  N   . PHE   A 1 285 ? 31.534  -2.232  13.158  1.00 32.98  ? 271 PHE   X N   1 
ATOM   2120 C  CA  . PHE   A 1 285 ? 31.568  -0.968  12.396  1.00 37.02  ? 271 PHE   X CA  1 
ATOM   2121 C  C   . PHE   A 1 285 ? 32.928  -0.283  12.630  1.00 40.96  ? 271 PHE   X C   1 
ATOM   2122 O  O   . PHE   A 1 285 ? 33.533  0.254   11.659  1.00 40.23  ? 271 PHE   X O   1 
ATOM   2123 C  CB  . PHE   A 1 285 ? 30.447  -0.040  12.850  1.00 39.70  ? 271 PHE   X CB  1 
ATOM   2124 C  CG  . PHE   A 1 285 ? 30.385  1.221   12.050  1.00 40.28  ? 271 PHE   X CG  1 
ATOM   2125 C  CD1 . PHE   A 1 285 ? 29.914  1.197   10.748  1.00 43.56  ? 271 PHE   X CD1 1 
ATOM   2126 C  CD2 . PHE   A 1 285 ? 30.838  2.427   12.586  1.00 42.34  ? 271 PHE   X CD2 1 
ATOM   2127 C  CE1 . PHE   A 1 285 ? 29.872  2.369   9.996   1.00 44.59  ? 271 PHE   X CE1 1 
ATOM   2128 C  CE2 . PHE   A 1 285 ? 30.800  3.588   11.835  1.00 41.77  ? 271 PHE   X CE2 1 
ATOM   2129 C  CZ  . PHE   A 1 285 ? 30.328  3.556   10.534  1.00 46.94  ? 271 PHE   X CZ  1 
ATOM   2130 N  N   . LYS   A 1 286 ? 33.420  -0.346  13.869  1.00 45.37  ? 272 LYS   X N   1 
ATOM   2131 C  CA  . LYS   A 1 286 ? 34.738  0.248   14.234  1.00 53.64  ? 272 LYS   X CA  1 
ATOM   2132 C  C   . LYS   A 1 286 ? 35.830  -0.367  13.357  1.00 50.91  ? 272 LYS   X C   1 
ATOM   2133 O  O   . LYS   A 1 286 ? 36.779  0.347   13.025  1.00 50.38  ? 272 LYS   X O   1 
ATOM   2134 C  CB  . LYS   A 1 286 ? 34.996  -0.017  15.714  1.00 65.22  ? 272 LYS   X CB  1 
ATOM   2135 C  CG  . LYS   A 1 286 ? 36.309  0.521   16.260  1.00 80.24  ? 272 LYS   X CG  1 
ATOM   2136 C  CD  . LYS   A 1 286 ? 36.163  1.142   17.641  1.00 89.24  ? 272 LYS   X CD  1 
ATOM   2137 C  CE  . LYS   A 1 286 ? 35.031  0.544   18.455  1.00 88.90  ? 272 LYS   X CE  1 
ATOM   2138 N  NZ  . LYS   A 1 286 ? 33.970  1.544   18.705  1.00 97.97  ? 272 LYS   X NZ  1 
ATOM   2139 N  N   . LYS   A 1 287 ? 35.715  -1.651  12.996  1.00 43.00  ? 273 LYS   X N   1 
ATOM   2140 C  CA  . LYS   A 1 287 ? 36.790  -2.345  12.244  1.00 45.98  ? 273 LYS   X CA  1 
ATOM   2141 C  C   . LYS   A 1 287 ? 36.650  -2.066  10.742  1.00 46.76  ? 273 LYS   X C   1 
ATOM   2142 O  O   . LYS   A 1 287 ? 37.622  -2.338  10.045  1.00 45.59  ? 273 LYS   X O   1 
ATOM   2143 C  CB  . LYS   A 1 287 ? 36.828  -3.830  12.614  1.00 51.44  ? 273 LYS   X CB  1 
ATOM   2144 C  CG  . LYS   A 1 287 ? 37.109  -4.056  14.102  1.00 63.77  ? 273 LYS   X CG  1 
ATOM   2145 C  CD  . LYS   A 1 287 ? 36.820  -5.448  14.622  1.00 74.44  ? 273 LYS   X CD  1 
ATOM   2146 C  CE  . LYS   A 1 287 ? 37.894  -6.443  14.247  1.00 84.71  ? 273 LYS   X CE  1 
ATOM   2147 N  NZ  . LYS   A 1 287 ? 37.314  -7.771  13.932  1.00 99.10  ? 273 LYS   X NZ  1 
ATOM   2148 N  N   . PHE   A 1 288 ? 35.526  -1.524  10.242  1.00 37.68  ? 274 PHE   X N   1 
ATOM   2149 C  CA  . PHE   A 1 288 ? 35.375  -1.257  8.784   1.00 38.90  ? 274 PHE   X CA  1 
ATOM   2150 C  C   . PHE   A 1 288 ? 36.337  -0.121  8.417   1.00 39.97  ? 274 PHE   X C   1 
ATOM   2151 O  O   . PHE   A 1 288 ? 36.580  0.764   9.247   1.00 42.23  ? 274 PHE   X O   1 
ATOM   2152 C  CB  . PHE   A 1 288 ? 33.968  -0.813  8.362   1.00 40.08  ? 274 PHE   X CB  1 
ATOM   2153 C  CG  . PHE   A 1 288 ? 32.850  -1.837  8.468   1.00 40.24  ? 274 PHE   X CG  1 
ATOM   2154 C  CD1 . PHE   A 1 288 ? 33.070  -3.186  8.206   1.00 43.72  ? 274 PHE   X CD1 1 
ATOM   2155 C  CD2 . PHE   A 1 288 ? 31.563  -1.431  8.772   1.00 38.49  ? 274 PHE   X CD2 1 
ATOM   2156 C  CE1 . PHE   A 1 288 ? 32.040  -4.118  8.281   1.00 42.83  ? 274 PHE   X CE1 1 
ATOM   2157 C  CE2 . PHE   A 1 288 ? 30.522  -2.359  8.832   1.00 41.79  ? 274 PHE   X CE2 1 
ATOM   2158 C  CZ  . PHE   A 1 288 ? 30.767  -3.701  8.611   1.00 42.57  ? 274 PHE   X CZ  1 
ATOM   2159 N  N   . ARG   A 1 289 ? 36.799  -0.110  7.184   1.00 41.80  ? 275 ARG   X N   1 
ATOM   2160 C  CA  . ARG   A 1 289 ? 37.466  1.062   6.560   1.00 43.72  ? 275 ARG   X CA  1 
ATOM   2161 C  C   . ARG   A 1 289 ? 36.341  1.932   6.028   1.00 38.24  ? 275 ARG   X C   1 
ATOM   2162 O  O   . ARG   A 1 289 ? 35.599  1.464   5.115   1.00 40.97  ? 275 ARG   X O   1 
ATOM   2163 C  CB  . ARG   A 1 289 ? 38.385  0.536   5.450   1.00 51.79  ? 275 ARG   X CB  1 
ATOM   2164 C  CG  . ARG   A 1 289 ? 39.256  1.563   4.748   1.00 57.28  ? 275 ARG   X CG  1 
ATOM   2165 C  CD  . ARG   A 1 289 ? 39.987  0.933   3.567   1.00 60.60  ? 275 ARG   X CD  1 
ATOM   2166 N  NE  . ARG   A 1 289 ? 40.514  -0.346  3.958   1.00 63.56  ? 275 ARG   X NE  1 
ATOM   2167 C  CZ  . ARG   A 1 289 ? 40.370  -1.510  3.342   1.00 56.79  ? 275 ARG   X CZ  1 
ATOM   2168 N  NH1 . ARG   A 1 289 ? 39.734  -1.643  2.208   1.00 60.32  ? 275 ARG   X NH1 1 
ATOM   2169 N  NH2 . ARG   A 1 289 ? 40.908  -2.578  3.878   1.00 65.22  ? 275 ARG   X NH2 1 
ATOM   2170 N  N   . LYS   A 1 290 ? 36.201  3.138   6.548   1.00 35.75  ? 276 LYS   X N   1 
ATOM   2171 C  CA  . LYS   A 1 290 ? 35.124  4.072   6.136   1.00 37.14  ? 276 LYS   X CA  1 
ATOM   2172 C  C   . LYS   A 1 290 ? 35.564  4.964   4.991   1.00 39.01  ? 276 LYS   X C   1 
ATOM   2173 O  O   . LYS   A 1 290 ? 36.776  4.990   4.675   1.00 38.39  ? 276 LYS   X O   1 
ATOM   2174 C  CB  . LYS   A 1 290 ? 34.713  4.984   7.272   1.00 41.44  ? 276 LYS   X CB  1 
ATOM   2175 C  CG  . LYS   A 1 290 ? 34.873  4.364   8.627   1.00 56.39  ? 276 LYS   X CG  1 
ATOM   2176 C  CD  . LYS   A 1 290 ? 33.855  3.316   8.935   1.00 44.12  ? 276 LYS   X CD  1 
ATOM   2177 C  CE  . LYS   A 1 290 ? 33.867  3.208   10.447  1.00 53.85  ? 276 LYS   X CE  1 
ATOM   2178 N  NZ  . LYS   A 1 290 ? 35.151  2.672   10.947  1.00 47.63  ? 276 LYS   X NZ  1 
ATOM   2179 N  N   . SER   A 1 291 ? 34.635  5.806   4.533   1.00 37.83  ? 277 SER   X N   1 
ATOM   2180 C  CA  . SER   A 1 291 ? 34.773  6.555   3.267   1.00 36.68  ? 277 SER   X CA  1 
ATOM   2181 C  C   . SER   A 1 291 ? 35.850  7.646   3.427   1.00 38.36  ? 277 SER   X C   1 
ATOM   2182 O  O   . SER   A 1 291 ? 36.244  8.236   2.393   1.00 41.26  ? 277 SER   X O   1 
ATOM   2183 C  CB  . SER   A 1 291 ? 33.474  7.148   2.815   1.00 34.49  ? 277 SER   X CB  1 
ATOM   2184 O  OG  . SER   A 1 291 ? 32.952  8.060   3.777   1.00 35.75  ? 277 SER   X OG  1 
ATOM   2185 N  N   . THR   A 1 292 ? 36.297  7.925   4.642   1.00 37.25  ? 278 THR   X N   1 
ATOM   2186 C  CA  . THR   A 1 292 ? 37.359  8.960   4.890   1.00 43.03  ? 278 THR   X CA  1 
ATOM   2187 C  C   . THR   A 1 292 ? 38.754  8.328   4.775   1.00 43.59  ? 278 THR   X C   1 
ATOM   2188 O  O   . THR   A 1 292 ? 39.746  9.080   4.749   1.00 42.14  ? 278 THR   X O   1 
ATOM   2189 C  CB  . THR   A 1 292 ? 37.133  9.655   6.242   1.00 44.82  ? 278 THR   X CB  1 
ATOM   2190 O  OG1 . THR   A 1 292 ? 36.828  8.644   7.209   1.00 51.16  ? 278 THR   X OG1 1 
ATOM   2191 C  CG2 . THR   A 1 292 ? 35.999  10.658  6.186   1.00 49.07  ? 278 THR   X CG2 1 
ATOM   2192 N  N   . GLU   A 1 293 ? 38.841  6.995   4.728   1.00 41.10  ? 279 GLU   X N   1 
ATOM   2193 C  CA  . GLU   A 1 293 ? 40.115  6.230   4.686   1.00 43.35  ? 279 GLU   X CA  1 
ATOM   2194 C  C   . GLU   A 1 293 ? 40.214  5.414   3.396   1.00 42.01  ? 279 GLU   X C   1 
ATOM   2195 O  O   . GLU   A 1 293 ? 41.349  5.027   3.025   1.00 36.62  ? 279 GLU   X O   1 
ATOM   2196 C  CB  . GLU   A 1 293 ? 40.225  5.318   5.917   1.00 45.31  ? 279 GLU   X CB  1 
ATOM   2197 C  CG  . GLU   A 1 293 ? 40.475  6.043   7.223   1.00 57.59  ? 279 GLU   X CG  1 
ATOM   2198 C  CD  . GLU   A 1 293 ? 39.182  6.334   7.968   1.00 81.04  ? 279 GLU   X CD  1 
ATOM   2199 O  OE1 . GLU   A 1 293 ? 38.927  7.549   8.275   1.00 86.57  ? 279 GLU   X OE1 1 
ATOM   2200 O  OE2 . GLU   A 1 293 ? 38.412  5.326   8.227   1.00 78.12  ? 279 GLU   X OE2 1 
ATOM   2201 N  N   . GLY   A 1 294 ? 39.089  5.030   2.784   1.00 35.86  ? 280 GLY   X N   1 
ATOM   2202 C  CA  . GLY   A 1 294 ? 39.136  4.183   1.592   1.00 35.20  ? 280 GLY   X CA  1 
ATOM   2203 C  C   . GLY   A 1 294 ? 37.880  3.373   1.348   1.00 38.80  ? 280 GLY   X C   1 
ATOM   2204 O  O   . GLY   A 1 294 ? 36.772  3.888   1.544   1.00 37.04  ? 280 GLY   X O   1 
ATOM   2205 N  N   . TYR   A 1 295 ? 38.080  2.180   0.823   1.00 36.38  ? 281 TYR   X N   1 
ATOM   2206 C  CA  . TYR   A 1 295 ? 37.049  1.408   0.093   1.00 37.16  ? 281 TYR   X CA  1 
ATOM   2207 C  C   . TYR   A 1 295 ? 37.501  -0.044  0.001   1.00 40.21  ? 281 TYR   X C   1 
ATOM   2208 O  O   . TYR   A 1 295 ? 38.644  -0.337  0.337   1.00 37.25  ? 281 TYR   X O   1 
ATOM   2209 C  CB  . TYR   A 1 295 ? 36.847  1.953   -1.316  1.00 36.25  ? 281 TYR   X CB  1 
ATOM   2210 C  CG  . TYR   A 1 295 ? 38.111  2.382   -2.018  1.00 39.37  ? 281 TYR   X CG  1 
ATOM   2211 C  CD1 . TYR   A 1 295 ? 39.021  1.470   -2.533  1.00 42.02  ? 281 TYR   X CD1 1 
ATOM   2212 C  CD2 . TYR   A 1 295 ? 38.385  3.735   -2.179  1.00 41.80  ? 281 TYR   X CD2 1 
ATOM   2213 C  CE1 . TYR   A 1 295 ? 40.191  1.881   -3.164  1.00 41.42  ? 281 TYR   X CE1 1 
ATOM   2214 C  CE2 . TYR   A 1 295 ? 39.498  4.160   -2.887  1.00 38.85  ? 281 TYR   X CE2 1 
ATOM   2215 C  CZ  . TYR   A 1 295 ? 40.418  3.239   -3.360  1.00 43.06  ? 281 TYR   X CZ  1 
ATOM   2216 O  OH  . TYR   A 1 295 ? 41.524  3.744   -4.013  1.00 46.86  ? 281 TYR   X OH  1 
ATOM   2217 N  N   . TYR   A 1 296 ? 36.633  -0.903  -0.521  1.00 37.17  ? 282 TYR   X N   1 
ATOM   2218 C  CA  . TYR   A 1 296 ? 36.852  -2.352  -0.667  1.00 39.13  ? 282 TYR   X CA  1 
ATOM   2219 C  C   . TYR   A 1 296 ? 36.764  -2.631  -2.166  1.00 37.75  ? 282 TYR   X C   1 
ATOM   2220 O  O   . TYR   A 1 296 ? 35.817  -2.142  -2.787  1.00 38.88  ? 282 TYR   X O   1 
ATOM   2221 C  CB  . TYR   A 1 296 ? 35.803  -3.133  0.145   1.00 37.63  ? 282 TYR   X CB  1 
ATOM   2222 C  CG  . TYR   A 1 296 ? 35.909  -3.007  1.641   1.00 37.08  ? 282 TYR   X CG  1 
ATOM   2223 C  CD1 . TYR   A 1 296 ? 35.333  -1.947  2.310   1.00 41.01  ? 282 TYR   X CD1 1 
ATOM   2224 C  CD2 . TYR   A 1 296 ? 36.631  -3.924  2.395   1.00 40.79  ? 282 TYR   X CD2 1 
ATOM   2225 C  CE1 . TYR   A 1 296 ? 35.444  -1.814  3.685   1.00 35.95  ? 282 TYR   X CE1 1 
ATOM   2226 C  CE2 . TYR   A 1 296 ? 36.781  -3.792  3.768   1.00 37.74  ? 282 TYR   X CE2 1 
ATOM   2227 C  CZ  . TYR   A 1 296 ? 36.143  -2.752  4.414   1.00 39.35  ? 282 TYR   X CZ  1 
ATOM   2228 O  OH  . TYR   A 1 296 ? 36.297  -2.565  5.751   1.00 40.58  ? 282 TYR   X OH  1 
ATOM   2229 N  N   . GLU   A 1 297 ? 37.784  -3.271  -2.732  1.00 39.09  ? 283 GLU   X N   1 
ATOM   2230 C  CA  . GLU   A 1 297 ? 37.718  -3.856  -4.080  1.00 44.63  ? 283 GLU   X CA  1 
ATOM   2231 C  C   . GLU   A 1 297 ? 37.809  -5.396  -3.933  1.00 39.39  ? 283 GLU   X C   1 
ATOM   2232 O  O   . GLU   A 1 297 ? 37.722  -5.816  -5.156  1.00 41.77  ? 283 GLU   X O   1 
ATOM   2233 C  CB  . GLU   A 1 297 ? 38.646  -3.092  -5.042  1.00 53.18  ? 283 GLU   X CB  1 
ATOM   2234 C  CG  . GLU   A 1 297 ? 40.118  -3.090  -4.781  1.00 65.49  ? 283 GLU   X CG  1 
ATOM   2235 C  CD  . GLU   A 1 297 ? 40.887  -2.284  -5.848  1.00 60.34  ? 283 GLU   X CD  1 
ATOM   2236 O  OE1 . GLU   A 1 297 ? 41.840  -2.827  -6.420  1.00 65.49  ? 283 GLU   X OE1 1 
ATOM   2237 O  OE2 . GLU   A 1 297 ? 40.539  -1.105  -6.092  1.00 53.12  ? 283 GLU   X OE2 1 
ATOM   2238 N  N   . ALA   B 1 22  ? -28.584 -30.857 27.985  1.00 66.33  ? 8   ALA   F N   1 
ATOM   2239 C  CA  . ALA   B 1 22  ? -27.463 -30.991 29.019  1.00 67.72  ? 8   ALA   F CA  1 
ATOM   2240 C  C   . ALA   B 1 22  ? -27.435 -29.752 29.924  1.00 62.88  ? 8   ALA   F C   1 
ATOM   2241 O  O   . ALA   B 1 22  ? -27.550 -28.617 29.365  1.00 54.34  ? 8   ALA   F O   1 
ATOM   2242 C  CB  . ALA   B 1 22  ? -26.120 -31.184 28.339  1.00 64.30  ? 8   ALA   F CB  1 
ATOM   2243 N  N   . ARG   B 1 23  ? -27.255 -29.966 31.246  1.00 67.27  ? 9   ARG   F N   1 
ATOM   2244 C  CA  . ARG   B 1 23  ? -27.188 -28.920 32.320  1.00 61.25  ? 9   ARG   F CA  1 
ATOM   2245 C  C   . ARG   B 1 23  ? -25.856 -29.033 33.066  1.00 54.21  ? 9   ARG   F C   1 
ATOM   2246 O  O   . ARG   B 1 23  ? -25.793 -29.344 34.268  1.00 43.58  ? 9   ARG   F O   1 
ATOM   2247 C  CB  . ARG   B 1 23  ? -28.373 -28.996 33.295  1.00 63.30  ? 9   ARG   F CB  1 
ATOM   2248 C  CG  . ARG   B 1 23  ? -29.751 -28.757 32.682  1.00 70.61  ? 9   ARG   F CG  1 
ATOM   2249 C  CD  . ARG   B 1 23  ? -29.797 -27.628 31.664  1.00 86.47  ? 9   ARG   F CD  1 
ATOM   2250 N  NE  . ARG   B 1 23  ? -31.020 -26.812 31.672  1.00 107.28 ? 9   ARG   F NE  1 
ATOM   2251 C  CZ  . ARG   B 1 23  ? -31.641 -26.307 30.590  1.00 105.33 ? 9   ARG   F CZ  1 
ATOM   2252 N  NH1 . ARG   B 1 23  ? -31.207 -26.552 29.360  1.00 106.89 ? 9   ARG   F NH1 1 
ATOM   2253 N  NH2 . ARG   B 1 23  ? -32.726 -25.568 30.747  1.00 110.87 ? 9   ARG   F NH2 1 
ATOM   2254 N  N   . PRO   B 1 24  ? -24.748 -28.677 32.381  1.00 49.41  ? 10  PRO   F N   1 
ATOM   2255 C  CA  . PRO   B 1 24  ? -23.421 -28.727 32.983  1.00 43.52  ? 10  PRO   F CA  1 
ATOM   2256 C  C   . PRO   B 1 24  ? -23.208 -27.683 34.077  1.00 43.10  ? 10  PRO   F C   1 
ATOM   2257 O  O   . PRO   B 1 24  ? -23.924 -26.695 34.141  1.00 42.28  ? 10  PRO   F O   1 
ATOM   2258 C  CB  . PRO   B 1 24  ? -22.436 -28.426 31.836  1.00 48.51  ? 10  PRO   F CB  1 
ATOM   2259 C  CG  . PRO   B 1 24  ? -23.271 -28.124 30.615  1.00 50.26  ? 10  PRO   F CG  1 
ATOM   2260 C  CD  . PRO   B 1 24  ? -24.726 -28.190 30.987  1.00 51.21  ? 10  PRO   F CD  1 
ATOM   2261 N  N   . LYS   B 1 25  ? -22.205 -27.925 34.910  1.00 36.59  ? 11  LYS   F N   1 
ATOM   2262 C  CA  . LYS   B 1 25  ? -21.681 -26.921 35.855  1.00 35.82  ? 11  LYS   F CA  1 
ATOM   2263 C  C   . LYS   B 1 25  ? -20.204 -26.666 35.574  1.00 34.88  ? 11  LYS   F C   1 
ATOM   2264 O  O   . LYS   B 1 25  ? -19.427 -27.624 35.534  1.00 36.93  ? 11  LYS   F O   1 
ATOM   2265 C  CB  . LYS   B 1 25  ? -21.879 -27.395 37.299  1.00 38.51  ? 11  LYS   F CB  1 
ATOM   2266 C  CG  . LYS   B 1 25  ? -23.326 -27.447 37.789  1.00 38.93  ? 11  LYS   F CG  1 
ATOM   2267 C  CD  . LYS   B 1 25  ? -23.371 -28.218 39.097  1.00 49.29  ? 11  LYS   F CD  1 
ATOM   2268 C  CE  . LYS   B 1 25  ? -24.584 -27.934 39.927  1.00 46.97  ? 11  LYS   F CE  1 
ATOM   2269 N  NZ  . LYS   B 1 25  ? -25.786 -28.322 39.193  1.00 54.78  ? 11  LYS   F NZ  1 
ATOM   2270 N  N   . LEU   B 1 26  ? -19.833 -25.407 35.389  1.00 36.63  ? 12  LEU   F N   1 
ATOM   2271 C  CA  . LEU   B 1 26  ? -18.434 -25.007 35.082  1.00 34.33  ? 12  LEU   F CA  1 
ATOM   2272 C  C   . LEU   B 1 26  ? -17.850 -24.321 36.318  1.00 32.80  ? 12  LEU   F C   1 
ATOM   2273 O  O   . LEU   B 1 26  ? -18.501 -23.399 36.851  1.00 35.12  ? 12  LEU   F O   1 
ATOM   2274 C  CB  . LEU   B 1 26  ? -18.415 -24.091 33.854  1.00 36.44  ? 12  LEU   F CB  1 
ATOM   2275 C  CG  . LEU   B 1 26  ? -17.057 -23.594 33.367  1.00 36.96  ? 12  LEU   F CG  1 
ATOM   2276 C  CD1 . LEU   B 1 26  ? -17.097 -23.299 31.858  1.00 38.91  ? 12  LEU   F CD1 1 
ATOM   2277 C  CD2 . LEU   B 1 26  ? -16.610 -22.342 34.131  1.00 37.40  ? 12  LEU   F CD2 1 
ATOM   2278 N  N   . TYR   B 1 27  ? -16.725 -24.844 36.786  1.00 31.80  ? 13  TYR   F N   1 
ATOM   2279 C  CA  . TYR   B 1 27  ? -15.984 -24.355 37.976  1.00 31.06  ? 13  TYR   F CA  1 
ATOM   2280 C  C   . TYR   B 1 27  ? -14.662 -23.729 37.570  1.00 35.96  ? 13  TYR   F C   1 
ATOM   2281 O  O   . TYR   B 1 27  ? -13.910 -24.351 36.802  1.00 37.05  ? 13  TYR   F O   1 
ATOM   2282 C  CB  . TYR   B 1 27  ? -15.677 -25.509 38.915  1.00 31.64  ? 13  TYR   F CB  1 
ATOM   2283 C  CG  . TYR   B 1 27  ? -16.860 -26.296 39.400  1.00 37.96  ? 13  TYR   F CG  1 
ATOM   2284 C  CD1 . TYR   B 1 27  ? -17.443 -27.281 38.618  1.00 39.09  ? 13  TYR   F CD1 1 
ATOM   2285 C  CD2 . TYR   B 1 27  ? -17.370 -26.076 40.685  1.00 36.57  ? 13  TYR   F CD2 1 
ATOM   2286 C  CE1 . TYR   B 1 27  ? -18.514 -28.032 39.092  1.00 38.06  ? 13  TYR   F CE1 1 
ATOM   2287 C  CE2 . TYR   B 1 27  ? -18.409 -26.843 41.173  1.00 35.70  ? 13  TYR   F CE2 1 
ATOM   2288 C  CZ  . TYR   B 1 27  ? -18.972 -27.827 40.382  1.00 39.56  ? 13  TYR   F CZ  1 
ATOM   2289 O  OH  . TYR   B 1 27  ? -20.052 -28.503 40.849  1.00 43.62  ? 13  TYR   F OH  1 
ATOM   2290 N  N   . VAL   B 1 28  ? -14.364 -22.583 38.163  1.00 33.18  ? 14  VAL   F N   1 
ATOM   2291 C  CA  . VAL   B 1 28  ? -13.042 -21.920 38.135  1.00 33.81  ? 14  VAL   F CA  1 
ATOM   2292 C  C   . VAL   B 1 28  ? -12.282 -22.317 39.399  1.00 35.92  ? 14  VAL   F C   1 
ATOM   2293 O  O   . VAL   B 1 28  ? -12.738 -21.946 40.509  1.00 38.39  ? 14  VAL   F O   1 
ATOM   2294 C  CB  . VAL   B 1 28  ? -13.219 -20.398 38.042  1.00 34.81  ? 14  VAL   F CB  1 
ATOM   2295 C  CG1 . VAL   B 1 28  ? -11.871 -19.690 38.035  1.00 37.70  ? 14  VAL   F CG1 1 
ATOM   2296 C  CG2 . VAL   B 1 28  ? -14.044 -20.006 36.818  1.00 39.39  ? 14  VAL   F CG2 1 
ATOM   2297 N  N   . MET   B 1 29  ? -11.114 -22.934 39.241  1.00 34.30  ? 15  MET   F N   1 
ATOM   2298 C  CA  . MET   B 1 29  ? -10.288 -23.386 40.382  1.00 37.43  ? 15  MET   F CA  1 
ATOM   2299 C  C   . MET   B 1 29  ? -9.032  -22.524 40.487  1.00 39.84  ? 15  MET   F C   1 
ATOM   2300 O  O   . MET   B 1 29  ? -8.293  -22.352 39.480  1.00 39.37  ? 15  MET   F O   1 
ATOM   2301 C  CB  . MET   B 1 29  ? -9.954  -24.872 40.246  1.00 37.36  ? 15  MET   F CB  1 
ATOM   2302 C  CG  . MET   B 1 29  ? -11.205 -25.748 40.321  1.00 38.17  ? 15  MET   F CG  1 
ATOM   2303 S  SD  . MET   B 1 29  ? -10.846 -27.472 39.972  1.00 39.63  ? 15  MET   F SD  1 
ATOM   2304 C  CE  . MET   B 1 29  ? -10.537 -27.351 38.198  1.00 40.57  ? 15  MET   F CE  1 
ATOM   2305 N  N   . ASP   B 1 30  ? -8.815  -21.942 41.661  1.00 38.08  ? 16  ASP   F N   1 
ATOM   2306 C  CA  . ASP   B 1 30  ? -7.671  -21.031 41.941  1.00 41.97  ? 16  ASP   F CA  1 
ATOM   2307 C  C   . ASP   B 1 30  ? -6.445  -21.901 42.236  1.00 43.90  ? 16  ASP   F C   1 
ATOM   2308 O  O   . ASP   B 1 30  ? -6.467  -22.623 43.271  1.00 37.09  ? 16  ASP   F O   1 
ATOM   2309 C  CB  . ASP   B 1 30  ? -8.062  -20.102 43.088  1.00 44.63  ? 16  ASP   F CB  1 
ATOM   2310 C  CG  . ASP   B 1 30  ? -7.059  -19.022 43.420  1.00 48.27  ? 16  ASP   F CG  1 
ATOM   2311 O  OD1 . ASP   B 1 30  ? -5.880  -19.230 43.152  1.00 43.10  ? 16  ASP   F OD1 1 
ATOM   2312 O  OD2 . ASP   B 1 30  ? -7.490  -17.979 43.959  1.00 48.06  ? 16  ASP   F OD2 1 
ATOM   2313 N  N   . ASN   B 1 31  ? -5.410  -21.847 41.377  1.00 38.74  ? 17  ASN   F N   1 
ATOM   2314 C  CA  . ASN   B 1 31  ? -4.208  -22.712 41.522  1.00 35.62  ? 17  ASN   F CA  1 
ATOM   2315 C  C   . ASN   B 1 31  ? -3.001  -21.858 41.883  1.00 38.77  ? 17  ASN   F C   1 
ATOM   2316 O  O   . ASN   B 1 31  ? -1.864  -22.278 41.607  1.00 42.11  ? 17  ASN   F O   1 
ATOM   2317 C  CB  . ASN   B 1 31  ? -3.959  -23.587 40.294  1.00 38.18  ? 17  ASN   F CB  1 
ATOM   2318 C  CG  . ASN   B 1 31  ? -5.125  -24.474 39.964  1.00 39.40  ? 17  ASN   F CG  1 
ATOM   2319 O  OD1 . ASN   B 1 31  ? -5.628  -24.459 38.846  1.00 38.25  ? 17  ASN   F OD1 1 
ATOM   2320 N  ND2 . ASN   B 1 31  ? -5.580  -25.238 40.942  1.00 41.29  ? 17  ASN   F ND2 1 
ATOM   2321 N  N   . GLY   B 1 32  ? -3.228  -20.720 42.527  1.00 37.23  ? 18  GLY   F N   1 
ATOM   2322 C  CA  . GLY   B 1 32  ? -2.146  -19.903 43.101  1.00 36.42  ? 18  GLY   F CA  1 
ATOM   2323 C  C   . GLY   B 1 32  ? -1.761  -18.746 42.201  1.00 37.15  ? 18  GLY   F C   1 
ATOM   2324 O  O   . GLY   B 1 32  ? -2.574  -18.377 41.349  1.00 38.35  ? 18  GLY   F O   1 
ATOM   2325 N  N   . ARG   B 1 33  ? -0.585  -18.175 42.437  1.00 37.52  ? 19  ARG   F N   1 
ATOM   2326 C  CA  . ARG   B 1 33  ? -0.127  -16.881 41.882  1.00 42.26  ? 19  ARG   F CA  1 
ATOM   2327 C  C   . ARG   B 1 33  ? 1.316   -17.058 41.387  1.00 41.04  ? 19  ARG   F C   1 
ATOM   2328 O  O   . ARG   B 1 33  ? 2.131   -17.798 42.013  1.00 43.01  ? 19  ARG   F O   1 
ATOM   2329 C  CB  . ARG   B 1 33  ? -0.184  -15.769 42.937  1.00 43.92  ? 19  ARG   F CB  1 
ATOM   2330 C  CG  . ARG   B 1 33  ? -1.548  -15.536 43.567  1.00 46.33  ? 19  ARG   F CG  1 
ATOM   2331 C  CD  . ARG   B 1 33  ? -2.508  -14.754 42.699  1.00 49.62  ? 19  ARG   F CD  1 
ATOM   2332 N  NE  . ARG   B 1 33  ? -3.845  -14.706 43.300  1.00 52.02  ? 19  ARG   F NE  1 
ATOM   2333 C  CZ  . ARG   B 1 33  ? -4.723  -15.727 43.324  1.00 56.13  ? 19  ARG   F CZ  1 
ATOM   2334 N  NH1 . ARG   B 1 33  ? -4.449  -16.892 42.746  1.00 47.82  ? 19  ARG   F NH1 1 
ATOM   2335 N  NH2 . ARG   B 1 33  ? -5.897  -15.570 43.915  1.00 52.58  ? 19  ARG   F NH2 1 
ATOM   2336 N  N   . MET   B 1 34  ? 1.633   -16.396 40.291  1.00 40.74  ? 20  MET   F N   1 
ATOM   2337 C  CA  . MET   B 1 34  ? 3.001   -16.314 39.747  1.00 40.19  ? 20  MET   F CA  1 
ATOM   2338 C  C   . MET   B 1 34  ? 3.378   -14.843 39.629  1.00 37.80  ? 20  MET   F C   1 
ATOM   2339 O  O   . MET   B 1 34  ? 2.473   -13.951 39.521  1.00 42.64  ? 20  MET   F O   1 
ATOM   2340 C  CB  . MET   B 1 34  ? 3.034   -17.025 38.394  1.00 42.97  ? 20  MET   F CB  1 
ATOM   2341 C  CG  . MET   B 1 34  ? 4.381   -17.048 37.732  1.00 44.74  ? 20  MET   F CG  1 
ATOM   2342 S  SD  . MET   B 1 34  ? 4.364   -18.169 36.274  1.00 46.09  ? 20  MET   F SD  1 
ATOM   2343 C  CE  . MET   B 1 34  ? 4.233   -19.790 37.030  1.00 38.30  ? 20  MET   F CE  1 
ATOM   2344 N  N   . ARG   B 1 35  ? 4.674   -14.580 39.654  1.00 37.86  ? 21  ARG   F N   1 
ATOM   2345 C  CA  . ARG   B 1 35  ? 5.202   -13.253 39.331  1.00 40.69  ? 21  ARG   F CA  1 
ATOM   2346 C  C   . ARG   B 1 35  ? 6.219   -13.423 38.211  1.00 40.22  ? 21  ARG   F C   1 
ATOM   2347 O  O   . ARG   B 1 35  ? 6.905   -14.490 38.167  1.00 38.34  ? 21  ARG   F O   1 
ATOM   2348 C  CB  . ARG   B 1 35  ? 5.838   -12.629 40.571  1.00 42.38  ? 21  ARG   F CB  1 
ATOM   2349 C  CG  . ARG   B 1 35  ? 4.850   -12.409 41.710  1.00 50.16  ? 21  ARG   F CG  1 
ATOM   2350 C  CD  . ARG   B 1 35  ? 5.526   -11.813 42.941  1.00 51.59  ? 21  ARG   F CD  1 
ATOM   2351 N  NE  . ARG   B 1 35  ? 6.384   -12.784 43.631  1.00 56.67  ? 21  ARG   F NE  1 
ATOM   2352 C  CZ  . ARG   B 1 35  ? 7.462   -12.464 44.385  1.00 60.33  ? 21  ARG   F CZ  1 
ATOM   2353 N  NH1 . ARG   B 1 35  ? 7.805   -11.198 44.583  1.00 59.49  ? 21  ARG   F NH1 1 
ATOM   2354 N  NH2 . ARG   B 1 35  ? 8.179   -13.414 44.949  1.00 60.42  ? 21  ARG   F NH2 1 
ATOM   2355 N  N   . MET   B 1 36  ? 6.320   -12.398 37.383  1.00 36.85  ? 22  MET   F N   1 
ATOM   2356 C  CA  . MET   B 1 36  ? 7.438   -12.289 36.426  1.00 37.62  ? 22  MET   F CA  1 
ATOM   2357 C  C   . MET   B 1 36  ? 7.569   -10.839 35.969  1.00 39.00  ? 22  MET   F C   1 
ATOM   2358 O  O   . MET   B 1 36  ? 6.653   -10.031 36.226  1.00 37.43  ? 22  MET   F O   1 
ATOM   2359 C  CB  . MET   B 1 36  ? 7.151   -13.197 35.232  1.00 38.19  ? 22  MET   F CB  1 
ATOM   2360 C  CG  . MET   B 1 36  ? 5.966   -12.727 34.395  1.00 36.43  ? 22  MET   F CG  1 
ATOM   2361 S  SD  . MET   B 1 36  ? 5.517   -13.997 33.154  1.00 43.89  ? 22  MET   F SD  1 
ATOM   2362 C  CE  . MET   B 1 36  ? 4.179   -13.116 32.358  1.00 45.20  ? 22  MET   F CE  1 
ATOM   2363 N  N   . ASP   B 1 37  ? 8.669   -10.557 35.272  1.00 40.60  ? 23  ASP   F N   1 
ATOM   2364 C  CA  . ASP   B 1 37  ? 8.934   -9.259  34.600  1.00 37.65  ? 23  ASP   F CA  1 
ATOM   2365 C  C   . ASP   B 1 37  ? 7.694   -8.898  33.796  1.00 37.36  ? 23  ASP   F C   1 
ATOM   2366 O  O   . ASP   B 1 37  ? 7.249   -9.743  32.982  1.00 39.31  ? 23  ASP   F O   1 
ATOM   2367 C  CB  . ASP   B 1 37  ? 10.214  -9.393  33.755  1.00 38.87  ? 23  ASP   F CB  1 
ATOM   2368 C  CG  . ASP   B 1 37  ? 10.805  -8.112  33.241  1.00 36.40  ? 23  ASP   F CG  1 
ATOM   2369 O  OD1 . ASP   B 1 37  ? 10.014  -7.161  32.932  1.00 39.38  ? 23  ASP   F OD1 1 
ATOM   2370 O  OD2 . ASP   B 1 37  ? 12.060  -8.097  33.095  1.00 39.91  ? 23  ASP   F OD2 1 
ATOM   2371 N  N   . LYS   B 1 38  ? 7.184   -7.673  33.935  1.00 36.77  ? 24  LYS   F N   1 
ATOM   2372 C  CA  . LYS   B 1 38  ? 6.003   -7.238  33.166  1.00 42.09  ? 24  LYS   F CA  1 
ATOM   2373 C  C   . LYS   B 1 38  ? 6.327   -7.245  31.663  1.00 39.53  ? 24  LYS   F C   1 
ATOM   2374 O  O   . LYS   B 1 38  ? 5.367   -7.321  30.865  1.00 39.52  ? 24  LYS   F O   1 
ATOM   2375 C  CB  . LYS   B 1 38  ? 5.550   -5.834  33.561  1.00 43.16  ? 24  LYS   F CB  1 
ATOM   2376 C  CG  . LYS   B 1 38  ? 4.121   -5.492  33.137  1.00 49.91  ? 24  LYS   F CG  1 
ATOM   2377 C  CD  . LYS   B 1 38  ? 3.788   -4.045  33.443  1.00 63.67  ? 24  LYS   F CD  1 
ATOM   2378 C  CE  . LYS   B 1 38  ? 2.596   -3.452  32.715  1.00 66.46  ? 24  LYS   F CE  1 
ATOM   2379 N  NZ  . LYS   B 1 38  ? 1.374   -4.249  32.913  1.00 64.26  ? 24  LYS   F NZ  1 
ATOM   2380 N  N   . ASN   B 1 39  ? 7.593   -7.085  31.276  1.00 43.84  ? 25  ASN   F N   1 
ATOM   2381 C  CA  . ASN   B 1 39  ? 8.000   -7.136  29.831  1.00 41.20  ? 25  ASN   F CA  1 
ATOM   2382 C  C   . ASN   B 1 39  ? 7.663   -8.490  29.195  1.00 37.76  ? 25  ASN   F C   1 
ATOM   2383 O  O   . ASN   B 1 39  ? 7.491   -8.491  27.989  1.00 41.73  ? 25  ASN   F O   1 
ATOM   2384 C  CB  . ASN   B 1 39  ? 9.465   -6.789  29.589  1.00 40.55  ? 25  ASN   F CB  1 
ATOM   2385 C  CG  . ASN   B 1 39  ? 9.722   -5.311  29.746  1.00 45.98  ? 25  ASN   F CG  1 
ATOM   2386 O  OD1 . ASN   B 1 39  ? 10.652  -4.897  30.447  1.00 58.20  ? 25  ASN   F OD1 1 
ATOM   2387 N  ND2 . ASN   B 1 39  ? 8.901   -4.516  29.111  1.00 40.21  ? 25  ASN   F ND2 1 
ATOM   2388 N  N   . TRP   B 1 40  ? 7.617   -9.592  29.945  1.00 37.96  ? 26  TRP   F N   1 
ATOM   2389 C  CA  . TRP   B 1 40  ? 7.133   -10.903 29.434  1.00 37.81  ? 26  TRP   F CA  1 
ATOM   2390 C  C   . TRP   B 1 40  ? 5.665   -10.731 29.048  1.00 41.06  ? 26  TRP   F C   1 
ATOM   2391 O  O   . TRP   B 1 40  ? 5.219   -11.403 28.112  1.00 36.97  ? 26  TRP   F O   1 
ATOM   2392 C  CB  . TRP   B 1 40  ? 7.275   -12.077 30.413  1.00 37.83  ? 26  TRP   F CB  1 
ATOM   2393 C  CG  . TRP   B 1 40  ? 8.665   -12.456 30.835  1.00 40.58  ? 26  TRP   F CG  1 
ATOM   2394 C  CD1 . TRP   B 1 40  ? 9.166   -12.379 32.110  1.00 47.10  ? 26  TRP   F CD1 1 
ATOM   2395 C  CD2 . TRP   B 1 40  ? 9.680   -13.105 30.060  1.00 43.84  ? 26  TRP   F CD2 1 
ATOM   2396 N  NE1 . TRP   B 1 40  ? 10.445  -12.862 32.169  1.00 44.52  ? 26  TRP   F NE1 1 
ATOM   2397 C  CE2 . TRP   B 1 40  ? 10.792  -13.313 30.916  1.00 52.97  ? 26  TRP   F CE2 1 
ATOM   2398 C  CE3 . TRP   B 1 40  ? 9.781   -13.522 28.728  1.00 47.12  ? 26  TRP   F CE3 1 
ATOM   2399 C  CZ2 . TRP   B 1 40  ? 11.977  -13.916 30.475  1.00 48.20  ? 26  TRP   F CZ2 1 
ATOM   2400 C  CZ3 . TRP   B 1 40  ? 10.956  -14.106 28.297  1.00 46.78  ? 26  TRP   F CZ3 1 
ATOM   2401 C  CH2 . TRP   B 1 40  ? 12.045  -14.281 29.152  1.00 47.85  ? 26  TRP   F CH2 1 
ATOM   2402 N  N   . MET   B 1 41  ? 4.920   -9.935  29.813  1.00 39.12  ? 27  MET   F N   1 
ATOM   2403 C  CA  . MET   B 1 41  ? 3.442   -9.891  29.739  1.00 43.16  ? 27  MET   F CA  1 
ATOM   2404 C  C   . MET   B 1 41  ? 3.047   -8.909  28.642  1.00 43.26  ? 27  MET   F C   1 
ATOM   2405 O  O   . MET   B 1 41  ? 2.122   -9.244  27.874  1.00 37.15  ? 27  MET   F O   1 
ATOM   2406 C  CB  . MET   B 1 41  ? 2.840   -9.418  31.068  1.00 51.22  ? 27  MET   F CB  1 
ATOM   2407 C  CG  . MET   B 1 41  ? 1.337   -9.494  31.137  1.00 60.45  ? 27  MET   F CG  1 
ATOM   2408 S  SD  . MET   B 1 41  ? 0.861   -11.032 31.965  1.00 90.74  ? 27  MET   F SD  1 
ATOM   2409 C  CE  . MET   B 1 41  ? 1.073   -10.542 33.671  1.00 67.11  ? 27  MET   F CE  1 
ATOM   2410 N  N   . ILE   B 1 42  ? 3.670   -7.721  28.651  1.00 38.16  ? 28  ILE   F N   1 
ATOM   2411 C  CA  . ILE   B 1 42  ? 3.444   -6.594  27.707  1.00 40.55  ? 28  ILE   F CA  1 
ATOM   2412 C  C   . ILE   B 1 42  ? 4.812   -6.132  27.151  1.00 45.40  ? 28  ILE   F C   1 
ATOM   2413 O  O   . ILE   B 1 42  ? 5.587   -5.460  27.898  1.00 37.90  ? 28  ILE   F O   1 
ATOM   2414 C  CB  . ILE   B 1 42  ? 2.664   -5.457  28.418  1.00 41.26  ? 28  ILE   F CB  1 
ATOM   2415 C  CG1 . ILE   B 1 42  ? 1.349   -5.908  29.069  1.00 43.92  ? 28  ILE   F CG1 1 
ATOM   2416 C  CG2 . ILE   B 1 42  ? 2.424   -4.328  27.462  1.00 37.82  ? 28  ILE   F CG2 1 
ATOM   2417 C  CD1 . ILE   B 1 42  ? 0.263   -6.348  28.070  1.00 44.47  ? 28  ILE   F CD1 1 
ATOM   2418 N  N   . ALA   B 1 43  ? 5.161   -6.533  25.919  1.00 42.60  ? 29  ALA   F N   1 
ATOM   2419 C  CA  . ALA   B 1 43  ? 6.480   -6.239  25.295  1.00 41.62  ? 29  ALA   F CA  1 
ATOM   2420 C  C   . ALA   B 1 43  ? 6.736   -4.732  25.351  1.00 42.41  ? 29  ALA   F C   1 
ATOM   2421 O  O   . ALA   B 1 43  ? 5.807   -3.956  25.002  1.00 42.91  ? 29  ALA   F O   1 
ATOM   2422 C  CB  . ALA   B 1 43  ? 6.542   -6.715  23.860  1.00 43.13  ? 29  ALA   F CB  1 
ATOM   2423 N  N   . MET   B 1 44  ? 7.943   -4.334  25.761  1.00 42.19  ? 30  MET   F N   1 
ATOM   2424 C  CA  . MET   B 1 44  ? 8.404   -2.924  25.713  1.00 41.64  ? 30  MET   F CA  1 
ATOM   2425 C  C   . MET   B 1 44  ? 7.364   -2.025  26.373  1.00 39.50  ? 30  MET   F C   1 
ATOM   2426 O  O   . MET   B 1 44  ? 7.017   -1.014  25.808  1.00 45.63  ? 30  MET   F O   1 
ATOM   2427 C  CB  . MET   B 1 44  ? 8.629   -2.494  24.265  1.00 44.49  ? 30  MET   F CB  1 
ATOM   2428 C  CG  . MET   B 1 44  ? 9.610   -3.398  23.562  1.00 43.29  ? 30  MET   F CG  1 
ATOM   2429 S  SD  . MET   B 1 44  ? 11.257  -3.499  24.313  1.00 47.55  ? 30  MET   F SD  1 
ATOM   2430 C  CE  . MET   B 1 44  ? 11.527  -1.748  24.612  1.00 46.25  ? 30  MET   F CE  1 
ATOM   2431 N  N   . HIS   B 1 45  ? 6.892   -2.386  27.560  1.00 42.76  ? 31  HIS   F N   1 
ATOM   2432 C  CA  . HIS   B 1 45  ? 5.783   -1.662  28.213  1.00 46.20  ? 31  HIS   F CA  1 
ATOM   2433 C  C   . HIS   B 1 45  ? 6.257   -0.295  28.686  1.00 44.86  ? 31  HIS   F C   1 
ATOM   2434 O  O   . HIS   B 1 45  ? 5.385   0.543   28.846  1.00 51.45  ? 31  HIS   F O   1 
ATOM   2435 C  CB  . HIS   B 1 45  ? 5.180   -2.447  29.388  1.00 48.41  ? 31  HIS   F CB  1 
ATOM   2436 C  CG  . HIS   B 1 45  ? 6.003   -2.414  30.633  1.00 49.77  ? 31  HIS   F CG  1 
ATOM   2437 N  ND1 . HIS   B 1 45  ? 5.667   -1.616  31.731  1.00 52.50  ? 31  HIS   F ND1 1 
ATOM   2438 C  CD2 . HIS   B 1 45  ? 7.117   -3.097  30.982  1.00 49.83  ? 31  HIS   F CD2 1 
ATOM   2439 C  CE1 . HIS   B 1 45  ? 6.566   -1.807  32.693  1.00 47.62  ? 31  HIS   F CE1 1 
ATOM   2440 N  NE2 . HIS   B 1 45  ? 7.459   -2.722  32.261  1.00 52.88  ? 31  HIS   F NE2 1 
ATOM   2441 N  N   . ASN   B 1 46  ? 7.559   -0.100  28.935  1.00 46.87  ? 32  ASN   F N   1 
ATOM   2442 C  CA  . ASN   B 1 46  ? 8.089   1.171   29.521  1.00 46.79  ? 32  ASN   F CA  1 
ATOM   2443 C  C   . ASN   B 1 46  ? 9.496   1.437   28.977  1.00 43.80  ? 32  ASN   F C   1 
ATOM   2444 O  O   . ASN   B 1 46  ? 10.492  1.289   29.693  1.00 45.42  ? 32  ASN   F O   1 
ATOM   2445 C  CB  . ASN   B 1 46  ? 8.017   1.117   31.051  1.00 50.10  ? 32  ASN   F CB  1 
ATOM   2446 C  CG  . ASN   B 1 46  ? 8.553   2.374   31.694  1.00 53.29  ? 32  ASN   F CG  1 
ATOM   2447 O  OD1 . ASN   B 1 46  ? 8.369   3.466   31.166  1.00 49.89  ? 32  ASN   F OD1 1 
ATOM   2448 N  ND2 . ASN   B 1 46  ? 9.310   2.213   32.761  1.00 58.24  ? 32  ASN   F ND2 1 
ATOM   2449 N  N   . PRO   B 1 47  ? 9.637   1.770   27.670  1.00 42.43  ? 33  PRO   F N   1 
ATOM   2450 C  CA  . PRO   B 1 47  ? 10.959  1.823   27.047  1.00 44.36  ? 33  PRO   F CA  1 
ATOM   2451 C  C   . PRO   B 1 47  ? 11.809  2.953   27.648  1.00 43.99  ? 33  PRO   F C   1 
ATOM   2452 O  O   . PRO   B 1 47  ? 11.263  3.990   27.980  1.00 38.78  ? 33  PRO   F O   1 
ATOM   2453 C  CB  . PRO   B 1 47  ? 10.682  2.118   25.567  1.00 45.57  ? 33  PRO   F CB  1 
ATOM   2454 C  CG  . PRO   B 1 47  ? 9.186   1.819   25.380  1.00 50.30  ? 33  PRO   F CG  1 
ATOM   2455 C  CD  . PRO   B 1 47  ? 8.553   2.100   26.729  1.00 47.97  ? 33  PRO   F CD  1 
ATOM   2456 N  N   . ALA   B 1 48  ? 13.108  2.711   27.755  1.00 46.20  ? 34  ALA   F N   1 
ATOM   2457 C  CA  . ALA   B 1 48  ? 14.135  3.722   28.072  1.00 44.83  ? 34  ALA   F CA  1 
ATOM   2458 C  C   . ALA   B 1 48  ? 14.030  4.919   27.115  1.00 45.03  ? 34  ALA   F C   1 
ATOM   2459 O  O   . ALA   B 1 48  ? 13.729  4.758   25.893  1.00 43.21  ? 34  ALA   F O   1 
ATOM   2460 C  CB  . ALA   B 1 48  ? 15.503  3.082   28.042  1.00 49.44  ? 34  ALA   F CB  1 
ATOM   2461 N  N   . THR   B 1 49  ? 14.274  6.113   27.664  1.00 46.26  ? 35  THR   F N   1 
ATOM   2462 C  CA  . THR   B 1 49  ? 14.314  7.416   26.953  1.00 45.17  ? 35  THR   F CA  1 
ATOM   2463 C  C   . THR   B 1 49  ? 15.610  8.161   27.349  1.00 44.44  ? 35  THR   F C   1 
ATOM   2464 O  O   . THR   B 1 49  ? 16.300  7.741   28.305  1.00 44.99  ? 35  THR   F O   1 
ATOM   2465 C  CB  . THR   B 1 49  ? 13.095  8.298   27.263  1.00 49.00  ? 35  THR   F CB  1 
ATOM   2466 O  OG1 . THR   B 1 49  ? 13.068  8.411   28.688  1.00 50.67  ? 35  THR   F OG1 1 
ATOM   2467 C  CG2 . THR   B 1 49  ? 11.779  7.749   26.747  1.00 46.16  ? 35  THR   F CG2 1 
ATOM   2468 N  N   . ILE   B 1 50  ? 15.963  9.190   26.589  1.00 44.36  ? 36  ILE   F N   1 
ATOM   2469 C  CA  . ILE   B 1 50  ? 17.157  10.042  26.875  1.00 50.27  ? 36  ILE   F CA  1 
ATOM   2470 C  C   . ILE   B 1 50  ? 17.029  10.581  28.322  1.00 55.14  ? 36  ILE   F C   1 
ATOM   2471 O  O   . ILE   B 1 50  ? 18.034  10.573  29.048  1.00 54.46  ? 36  ILE   F O   1 
ATOM   2472 C  CB  . ILE   B 1 50  ? 17.292  11.112  25.773  1.00 59.57  ? 36  ILE   F CB  1 
ATOM   2473 C  CG1 . ILE   B 1 50  ? 18.671  11.779  25.794  1.00 67.52  ? 36  ILE   F CG1 1 
ATOM   2474 C  CG2 . ILE   B 1 50  ? 16.145  12.116  25.836  1.00 58.71  ? 36  ILE   F CG2 1 
ATOM   2475 C  CD1 . ILE   B 1 50  ? 18.946  12.677  24.597  1.00 75.14  ? 36  ILE   F CD1 1 
ATOM   2476 N  N   . HIS   B 1 51  ? 15.810  10.869  28.797  1.00 53.15  ? 37  HIS   F N   1 
ATOM   2477 C  CA  . HIS   B 1 51  ? 15.521  11.298  30.194  1.00 58.14  ? 37  HIS   F CA  1 
ATOM   2478 C  C   . HIS   B 1 51  ? 15.480  10.108  31.166  1.00 61.91  ? 37  HIS   F C   1 
ATOM   2479 O  O   . HIS   B 1 51  ? 15.815  10.311  32.329  1.00 56.15  ? 37  HIS   F O   1 
ATOM   2480 C  CB  . HIS   B 1 51  ? 14.281  12.206  30.204  1.00 65.72  ? 37  HIS   F CB  1 
ATOM   2481 C  CG  . HIS   B 1 51  ? 14.582  13.528  29.567  1.00 81.18  ? 37  HIS   F CG  1 
ATOM   2482 N  ND1 . HIS   B 1 51  ? 14.047  13.913  28.336  1.00 94.16  ? 37  HIS   F ND1 1 
ATOM   2483 C  CD2 . HIS   B 1 51  ? 15.439  14.515  29.925  1.00 85.23  ? 37  HIS   F CD2 1 
ATOM   2484 C  CE1 . HIS   B 1 51  ? 14.524  15.094  27.993  1.00 81.09  ? 37  HIS   F CE1 1 
ATOM   2485 N  NE2 . HIS   B 1 51  ? 15.375  15.487  28.955  1.00 88.65  ? 37  HIS   F NE2 1 
ATOM   2486 N  N   . ASN   B 1 52  ? 15.127  8.893   30.744  1.00 56.41  ? 38  ASN   F N   1 
ATOM   2487 C  CA  . ASN   B 1 52  ? 15.064  7.719   31.657  1.00 47.36  ? 38  ASN   F CA  1 
ATOM   2488 C  C   . ASN   B 1 52  ? 15.855  6.579   31.020  1.00 50.01  ? 38  ASN   F C   1 
ATOM   2489 O  O   . ASN   B 1 52  ? 15.276  5.536   30.718  1.00 47.61  ? 38  ASN   F O   1 
ATOM   2490 C  CB  . ASN   B 1 52  ? 13.606  7.386   32.060  1.00 49.73  ? 38  ASN   F CB  1 
ATOM   2491 C  CG  . ASN   B 1 52  ? 13.470  6.295   33.113  1.00 49.59  ? 38  ASN   F CG  1 
ATOM   2492 O  OD1 . ASN   B 1 52  ? 14.397  6.014   33.860  1.00 51.87  ? 38  ASN   F OD1 1 
ATOM   2493 N  ND2 . ASN   B 1 52  ? 12.343  5.601   33.143  1.00 53.45  ? 38  ASN   F ND2 1 
ATOM   2494 N  N   . PRO   B 1 53  ? 17.194  6.734   30.834  1.00 50.49  ? 39  PRO   F N   1 
ATOM   2495 C  CA  . PRO   B 1 53  ? 18.002  5.790   30.058  1.00 51.79  ? 39  PRO   F CA  1 
ATOM   2496 C  C   . PRO   B 1 53  ? 18.158  4.418   30.721  1.00 48.34  ? 39  PRO   F C   1 
ATOM   2497 O  O   . PRO   B 1 53  ? 18.525  3.471   30.016  1.00 51.70  ? 39  PRO   F O   1 
ATOM   2498 C  CB  . PRO   B 1 53  ? 19.383  6.477   29.930  1.00 51.18  ? 39  PRO   F CB  1 
ATOM   2499 C  CG  . PRO   B 1 53  ? 19.451  7.380   31.150  1.00 54.10  ? 39  PRO   F CG  1 
ATOM   2500 C  CD  . PRO   B 1 53  ? 18.020  7.844   31.356  1.00 54.69  ? 39  PRO   F CD  1 
ATOM   2501 N  N   . ASN   B 1 54  ? 17.937  4.340   32.031  1.00 42.83  ? 40  ASN   F N   1 
ATOM   2502 C  CA  . ASN   B 1 54  ? 18.064  3.077   32.803  1.00 48.16  ? 40  ASN   F CA  1 
ATOM   2503 C  C   . ASN   B 1 54  ? 16.694  2.677   33.349  1.00 49.08  ? 40  ASN   F C   1 
ATOM   2504 O  O   . ASN   B 1 54  ? 16.632  2.194   34.490  1.00 45.78  ? 40  ASN   F O   1 
ATOM   2505 C  CB  . ASN   B 1 54  ? 19.107  3.195   33.911  1.00 57.31  ? 40  ASN   F CB  1 
ATOM   2506 C  CG  . ASN   B 1 54  ? 20.465  3.503   33.328  1.00 53.59  ? 40  ASN   F CG  1 
ATOM   2507 O  OD1 . ASN   B 1 54  ? 20.996  2.718   32.549  1.00 54.29  ? 40  ASN   F OD1 1 
ATOM   2508 N  ND2 . ASN   B 1 54  ? 20.985  4.673   33.634  1.00 58.48  ? 40  ASN   F ND2 1 
ATOM   2509 N  N   . ALA   B 1 55  ? 15.654  2.825   32.527  1.00 47.31  ? 41  ALA   F N   1 
ATOM   2510 C  CA  . ALA   B 1 55  ? 14.246  2.544   32.895  1.00 45.20  ? 41  ALA   F CA  1 
ATOM   2511 C  C   . ALA   B 1 55  ? 14.137  1.170   33.562  1.00 45.57  ? 41  ALA   F C   1 
ATOM   2512 O  O   . ALA   B 1 55  ? 14.813  0.188   33.144  1.00 44.58  ? 41  ALA   F O   1 
ATOM   2513 C  CB  . ALA   B 1 55  ? 13.326  2.660   31.711  1.00 43.80  ? 41  ALA   F CB  1 
ATOM   2514 N  N   . GLN   B 1 56  ? 13.342  1.159   34.620  1.00 44.82  ? 42  GLN   F N   1 
ATOM   2515 C  CA  . GLN   B 1 56  ? 13.103  -0.004  35.497  1.00 50.79  ? 42  GLN   F CA  1 
ATOM   2516 C  C   . GLN   B 1 56  ? 11.855  -0.718  35.013  1.00 40.40  ? 42  GLN   F C   1 
ATOM   2517 O  O   . GLN   B 1 56  ? 10.896  -0.045  34.623  1.00 43.51  ? 42  GLN   F O   1 
ATOM   2518 C  CB  . GLN   B 1 56  ? 12.878  0.456   36.940  1.00 54.28  ? 42  GLN   F CB  1 
ATOM   2519 C  CG  . GLN   B 1 56  ? 14.181  0.743   37.660  1.00 64.08  ? 42  GLN   F CG  1 
ATOM   2520 C  CD  . GLN   B 1 56  ? 13.923  1.380   38.999  1.00 64.46  ? 42  GLN   F CD  1 
ATOM   2521 O  OE1 . GLN   B 1 56  ? 12.994  1.001   39.717  1.00 61.13  ? 42  GLN   F OE1 1 
ATOM   2522 N  NE2 . GLN   B 1 56  ? 14.741  2.370   39.315  1.00 63.80  ? 42  GLN   F NE2 1 
ATOM   2523 N  N   . THR   B 1 57  ? 11.859  -2.030  35.091  1.00 43.88  ? 43  THR   F N   1 
ATOM   2524 C  CA  . THR   B 1 57  ? 10.628  -2.816  34.879  1.00 47.22  ? 43  THR   F CA  1 
ATOM   2525 C  C   . THR   B 1 57  ? 9.951   -2.956  36.254  1.00 50.71  ? 43  THR   F C   1 
ATOM   2526 O  O   . THR   B 1 57  ? 10.371  -2.279  37.229  1.00 46.45  ? 43  THR   F O   1 
ATOM   2527 C  CB  . THR   B 1 57  ? 10.947  -4.139  34.163  1.00 42.59  ? 43  THR   F CB  1 
ATOM   2528 O  OG1 . THR   B 1 57  ? 9.714   -4.771  33.818  1.00 40.70  ? 43  THR   F OG1 1 
ATOM   2529 C  CG2 . THR   B 1 57  ? 11.782  -5.080  34.996  1.00 42.10  ? 43  THR   F CG2 1 
ATOM   2530 N  N   . GLU   B 1 58  ? 8.966   -3.833  36.341  1.00 46.80  ? 44  GLU   F N   1 
ATOM   2531 C  CA  . GLU   B 1 58  ? 8.303   -4.215  37.619  1.00 56.08  ? 44  GLU   F CA  1 
ATOM   2532 C  C   . GLU   B 1 58  ? 8.003   -5.711  37.546  1.00 48.03  ? 44  GLU   F C   1 
ATOM   2533 O  O   . GLU   B 1 58  ? 8.063   -6.272  36.441  1.00 41.70  ? 44  GLU   F O   1 
ATOM   2534 C  CB  . GLU   B 1 58  ? 7.068   -3.341  37.873  1.00 57.34  ? 44  GLU   F CB  1 
ATOM   2535 C  CG  . GLU   B 1 58  ? 6.261   -3.103  36.632  1.00 65.55  ? 44  GLU   F CG  1 
ATOM   2536 C  CD  . GLU   B 1 58  ? 4.921   -2.414  36.816  1.00 87.24  ? 44  GLU   F CD  1 
ATOM   2537 O  OE1 . GLU   B 1 58  ? 4.181   -2.770  37.770  1.00 90.22  ? 44  GLU   F OE1 1 
ATOM   2538 O  OE2 . GLU   B 1 58  ? 4.597   -1.558  35.964  1.00 94.79  ? 44  GLU   F OE2 1 
ATOM   2539 N  N   . PHE   B 1 59  ? 7.768   -6.323  38.703  1.00 41.62  ? 45  PHE   F N   1 
ATOM   2540 C  CA  . PHE   B 1 59  ? 7.669   -7.786  38.886  1.00 43.74  ? 45  PHE   F CA  1 
ATOM   2541 C  C   . PHE   B 1 59  ? 6.215   -8.046  39.264  1.00 51.24  ? 45  PHE   F C   1 
ATOM   2542 O  O   . PHE   B 1 59  ? 5.872   -7.799  40.448  1.00 51.49  ? 45  PHE   F O   1 
ATOM   2543 C  CB  . PHE   B 1 59  ? 8.687   -8.229  39.934  1.00 43.54  ? 45  PHE   F CB  1 
ATOM   2544 C  CG  . PHE   B 1 59  ? 9.117   -9.669  39.900  1.00 45.25  ? 45  PHE   F CG  1 
ATOM   2545 C  CD1 . PHE   B 1 59  ? 9.688   -10.218 38.761  1.00 42.10  ? 45  PHE   F CD1 1 
ATOM   2546 C  CD2 . PHE   B 1 59  ? 8.975   -10.477 41.017  1.00 46.01  ? 45  PHE   F CD2 1 
ATOM   2547 C  CE1 . PHE   B 1 59  ? 10.120  -11.535 38.749  1.00 43.91  ? 45  PHE   F CE1 1 
ATOM   2548 C  CE2 . PHE   B 1 59  ? 9.387   -11.803 40.997  1.00 48.60  ? 45  PHE   F CE2 1 
ATOM   2549 C  CZ  . PHE   B 1 59  ? 9.960   -12.331 39.860  1.00 51.39  ? 45  PHE   F CZ  1 
ATOM   2550 N  N   . VAL   B 1 60  ? 5.377   -8.413  38.288  1.00 46.47  ? 46  VAL   F N   1 
ATOM   2551 C  CA  . VAL   B 1 60  ? 3.894   -8.327  38.422  1.00 42.27  ? 46  VAL   F CA  1 
ATOM   2552 C  C   . VAL   B 1 60  ? 3.342   -9.697  38.776  1.00 42.95  ? 46  VAL   F C   1 
ATOM   2553 O  O   . VAL   B 1 60  ? 3.899   -10.718 38.357  1.00 41.04  ? 46  VAL   F O   1 
ATOM   2554 C  CB  . VAL   B 1 60  ? 3.188   -7.774  37.172  1.00 50.49  ? 46  VAL   F CB  1 
ATOM   2555 C  CG1 . VAL   B 1 60  ? 3.480   -6.306  36.966  1.00 53.86  ? 46  VAL   F CG1 1 
ATOM   2556 C  CG2 . VAL   B 1 60  ? 3.520   -8.580  35.923  1.00 48.67  ? 46  VAL   F CG2 1 
ATOM   2557 N  N   . GLU   B 1 61  ? 2.273   -9.685  39.562  1.00 42.73  ? 47  GLU   F N   1 
ATOM   2558 C  CA  . GLU   B 1 61  ? 1.631   -10.890 40.123  1.00 41.40  ? 47  GLU   F CA  1 
ATOM   2559 C  C   . GLU   B 1 61  ? 0.374   -11.230 39.321  1.00 37.45  ? 47  GLU   F C   1 
ATOM   2560 O  O   . GLU   B 1 61  ? -0.392  -10.340 38.962  1.00 42.09  ? 47  GLU   F O   1 
ATOM   2561 C  CB  . GLU   B 1 61  ? 1.285   -10.703 41.608  1.00 44.84  ? 47  GLU   F CB  1 
ATOM   2562 C  CG  . GLU   B 1 61  ? 0.944   -12.041 42.245  1.00 49.81  ? 47  GLU   F CG  1 
ATOM   2563 C  CD  . GLU   B 1 61  ? 0.518   -12.068 43.704  1.00 52.57  ? 47  GLU   F CD  1 
ATOM   2564 O  OE1 . GLU   B 1 61  ? -0.582  -11.586 44.030  1.00 56.86  ? 47  GLU   F OE1 1 
ATOM   2565 O  OE2 . GLU   B 1 61  ? 1.260   -12.665 44.476  1.00 50.02  ? 47  GLU   F OE2 1 
ATOM   2566 N  N   . PHE   B 1 62  ? 0.120   -12.509 39.097  1.00 39.43  ? 48  PHE   F N   1 
ATOM   2567 C  CA  . PHE   B 1 62  ? -1.033  -12.923 38.269  1.00 39.17  ? 48  PHE   F CA  1 
ATOM   2568 C  C   . PHE   B 1 62  ? -1.478  -14.317 38.699  1.00 36.13  ? 48  PHE   F C   1 
ATOM   2569 O  O   . PHE   B 1 62  ? -0.690  -15.114 39.194  1.00 41.12  ? 48  PHE   F O   1 
ATOM   2570 C  CB  . PHE   B 1 62  ? -0.660  -12.780 36.777  1.00 40.17  ? 48  PHE   F CB  1 
ATOM   2571 C  CG  . PHE   B 1 62  ? 0.504   -13.616 36.322  1.00 38.69  ? 48  PHE   F CG  1 
ATOM   2572 C  CD1 . PHE   B 1 62  ? 0.335   -14.934 35.919  1.00 39.52  ? 48  PHE   F CD1 1 
ATOM   2573 C  CD2 . PHE   B 1 62  ? 1.785   -13.091 36.331  1.00 41.43  ? 48  PHE   F CD2 1 
ATOM   2574 C  CE1 . PHE   B 1 62  ? 1.418   -15.698 35.491  1.00 41.72  ? 48  PHE   F CE1 1 
ATOM   2575 C  CE2 . PHE   B 1 62  ? 2.862   -13.855 35.914  1.00 43.66  ? 48  PHE   F CE2 1 
ATOM   2576 C  CZ  . PHE   B 1 62  ? 2.683   -15.159 35.506  1.00 41.99  ? 48  PHE   F CZ  1 
ATOM   2577 N  N   . PRO   B 1 63  ? -2.765  -14.635 38.484  1.00 36.76  ? 49  PRO   F N   1 
ATOM   2578 C  CA  . PRO   B 1 63  ? -3.331  -15.924 38.817  1.00 35.41  ? 49  PRO   F CA  1 
ATOM   2579 C  C   . PRO   B 1 63  ? -2.996  -17.035 37.824  1.00 38.47  ? 49  PRO   F C   1 
ATOM   2580 O  O   . PRO   B 1 63  ? -2.919  -16.791 36.637  1.00 38.85  ? 49  PRO   F O   1 
ATOM   2581 C  CB  . PRO   B 1 63  ? -4.837  -15.678 38.727  1.00 36.51  ? 49  PRO   F CB  1 
ATOM   2582 C  CG  . PRO   B 1 63  ? -4.966  -14.601 37.711  1.00 37.03  ? 49  PRO   F CG  1 
ATOM   2583 C  CD  . PRO   B 1 63  ? -3.751  -13.728 37.871  1.00 39.54  ? 49  PRO   F CD  1 
ATOM   2584 N  N   . ILE   B 1 64  ? -2.842  -18.230 38.366  1.00 36.39  ? 50  ILE   F N   1 
ATOM   2585 C  CA  . ILE   B 1 64  ? -2.844  -19.498 37.594  1.00 37.41  ? 50  ILE   F CA  1 
ATOM   2586 C  C   . ILE   B 1 64  ? -4.176  -20.142 37.937  1.00 41.86  ? 50  ILE   F C   1 
ATOM   2587 O  O   . ILE   B 1 64  ? -4.453  -20.266 39.169  1.00 40.30  ? 50  ILE   F O   1 
ATOM   2588 C  CB  . ILE   B 1 64  ? -1.666  -20.402 37.996  1.00 38.59  ? 50  ILE   F CB  1 
ATOM   2589 C  CG1 . ILE   B 1 64  ? -0.327  -19.647 38.069  1.00 41.78  ? 50  ILE   F CG1 1 
ATOM   2590 C  CG2 . ILE   B 1 64  ? -1.600  -21.633 37.111  1.00 39.10  ? 50  ILE   F CG2 1 
ATOM   2591 C  CD1 . ILE   B 1 64  ? 0.166   -19.122 36.771  1.00 43.20  ? 50  ILE   F CD1 1 
ATOM   2592 N  N   . TYR   B 1 65  ? -4.960  -20.544 36.936  1.00 33.96  ? 51  TYR   F N   1 
ATOM   2593 C  CA  . TYR   B 1 65  ? -6.240  -21.234 37.176  1.00 34.01  ? 51  TYR   F CA  1 
ATOM   2594 C  C   . TYR   B 1 65  ? -6.535  -22.274 36.112  1.00 35.51  ? 51  TYR   F C   1 
ATOM   2595 O  O   . TYR   B 1 65  ? -5.878  -22.331 35.085  1.00 32.87  ? 51  TYR   F O   1 
ATOM   2596 C  CB  . TYR   B 1 65  ? -7.400  -20.246 37.273  1.00 33.50  ? 51  TYR   F CB  1 
ATOM   2597 C  CG  . TYR   B 1 65  ? -7.858  -19.588 36.003  1.00 34.69  ? 51  TYR   F CG  1 
ATOM   2598 C  CD1 . TYR   B 1 65  ? -7.226  -18.460 35.495  1.00 37.33  ? 51  TYR   F CD1 1 
ATOM   2599 C  CD2 . TYR   B 1 65  ? -9.000  -20.040 35.357  1.00 37.13  ? 51  TYR   F CD2 1 
ATOM   2600 C  CE1 . TYR   B 1 65  ? -7.697  -17.833 34.346  1.00 35.74  ? 51  TYR   F CE1 1 
ATOM   2601 C  CE2 . TYR   B 1 65  ? -9.483  -19.436 34.206  1.00 38.86  ? 51  TYR   F CE2 1 
ATOM   2602 C  CZ  . TYR   B 1 65  ? -8.833  -18.321 33.698  1.00 37.13  ? 51  TYR   F CZ  1 
ATOM   2603 O  OH  . TYR   B 1 65  ? -9.362  -17.749 32.566  1.00 34.62  ? 51  TYR   F OH  1 
ATOM   2604 N  N   . THR   B 1 66  ? -7.521  -23.085 36.428  1.00 32.65  ? 52  THR   F N   1 
ATOM   2605 C  CA  . THR   B 1 66  ? -7.992  -24.222 35.632  1.00 32.99  ? 52  THR   F CA  1 
ATOM   2606 C  C   . THR   B 1 66  ? -9.518  -24.195 35.657  1.00 36.32  ? 52  THR   F C   1 
ATOM   2607 O  O   . THR   B 1 66  ? -10.114 -23.522 36.535  1.00 34.20  ? 52  THR   F O   1 
ATOM   2608 C  CB  . THR   B 1 66  ? -7.425  -25.549 36.143  1.00 40.87  ? 52  THR   F CB  1 
ATOM   2609 O  OG1 . THR   B 1 66  ? -7.779  -25.675 37.511  1.00 38.62  ? 52  THR   F OG1 1 
ATOM   2610 C  CG2 . THR   B 1 66  ? -5.925  -25.681 35.983  1.00 39.53  ? 52  THR   F CG2 1 
ATOM   2611 N  N   . VAL   B 1 67  ? -10.144 -24.825 34.677  1.00 36.33  ? 53  VAL   F N   1 
ATOM   2612 C  CA  . VAL   B 1 67  ? -11.617 -24.831 34.557  1.00 35.32  ? 53  VAL   F CA  1 
ATOM   2613 C  C   . VAL   B 1 67  ? -12.047 -26.287 34.461  1.00 35.26  ? 53  VAL   F C   1 
ATOM   2614 O  O   . VAL   B 1 67  ? -11.492 -27.009 33.615  1.00 35.39  ? 53  VAL   F O   1 
ATOM   2615 C  CB  . VAL   B 1 67  ? -12.087 -23.998 33.358  1.00 35.61  ? 53  VAL   F CB  1 
ATOM   2616 C  CG1 . VAL   B 1 67  ? -13.554 -24.223 33.076  1.00 36.66  ? 53  VAL   F CG1 1 
ATOM   2617 C  CG2 . VAL   B 1 67  ? -11.793 -22.505 33.543  1.00 36.01  ? 53  VAL   F CG2 1 
ATOM   2618 N  N   . LEU   B 1 68  ? -13.009 -26.682 35.296  1.00 33.82  ? 54  LEU   F N   1 
ATOM   2619 C  CA  . LEU   B 1 68  ? -13.681 -28.003 35.241  1.00 33.33  ? 54  LEU   F CA  1 
ATOM   2620 C  C   . LEU   B 1 68  ? -15.080 -27.821 34.680  1.00 35.81  ? 54  LEU   F C   1 
ATOM   2621 O  O   . LEU   B 1 68  ? -15.855 -27.012 35.220  1.00 35.04  ? 54  LEU   F O   1 
ATOM   2622 C  CB  . LEU   B 1 68  ? -13.745 -28.639 36.631  1.00 36.26  ? 54  LEU   F CB  1 
ATOM   2623 C  CG  . LEU   B 1 68  ? -14.526 -29.953 36.702  1.00 36.80  ? 54  LEU   F CG  1 
ATOM   2624 C  CD1 . LEU   B 1 68  ? -13.745 -31.071 36.028  1.00 41.32  ? 54  LEU   F CD1 1 
ATOM   2625 C  CD2 . LEU   B 1 68  ? -14.816 -30.332 38.169  1.00 40.70  ? 54  LEU   F CD2 1 
ATOM   2626 N  N   . ILE   B 1 69  ? -15.407 -28.566 33.626  1.00 35.29  ? 55  ILE   F N   1 
ATOM   2627 C  CA  . ILE   B 1 69  ? -16.792 -28.640 33.127  1.00 38.91  ? 55  ILE   F CA  1 
ATOM   2628 C  C   . ILE   B 1 69  ? -17.345 -29.989 33.572  1.00 43.04  ? 55  ILE   F C   1 
ATOM   2629 O  O   . ILE   B 1 69  ? -16.969 -31.039 32.995  1.00 37.92  ? 55  ILE   F O   1 
ATOM   2630 C  CB  . ILE   B 1 69  ? -16.878 -28.405 31.607  1.00 43.42  ? 55  ILE   F CB  1 
ATOM   2631 C  CG1 . ILE   B 1 69  ? -16.256 -27.059 31.199  1.00 46.14  ? 55  ILE   F CG1 1 
ATOM   2632 C  CG2 . ILE   B 1 69  ? -18.312 -28.483 31.152  1.00 40.14  ? 55  ILE   F CG2 1 
ATOM   2633 C  CD1 . ILE   B 1 69  ? -14.783 -27.111 30.944  1.00 55.57  ? 55  ILE   F CD1 1 
ATOM   2634 N  N   . ASP   B 1 70  ? -18.193 -29.965 34.597  1.00 40.22  ? 56  ASP   F N   1 
ATOM   2635 C  CA  . ASP   B 1 70  ? -18.930 -31.179 35.032  1.00 41.00  ? 56  ASP   F CA  1 
ATOM   2636 C  C   . ASP   B 1 70  ? -20.120 -31.346 34.080  1.00 40.53  ? 56  ASP   F C   1 
ATOM   2637 O  O   . ASP   B 1 70  ? -21.145 -30.734 34.272  1.00 40.79  ? 56  ASP   F O   1 
ATOM   2638 C  CB  . ASP   B 1 70  ? -19.301 -31.108 36.513  1.00 43.44  ? 56  ASP   F CB  1 
ATOM   2639 C  CG  . ASP   B 1 70  ? -19.960 -32.381 37.007  1.00 47.45  ? 56  ASP   F CG  1 
ATOM   2640 O  OD1 . ASP   B 1 70  ? -19.909 -33.400 36.276  1.00 44.85  ? 56  ASP   F OD1 1 
ATOM   2641 O  OD2 . ASP   B 1 70  ? -20.532 -32.338 38.108  1.00 50.27  ? 56  ASP   F OD2 1 
ATOM   2642 N  N   . HIS   B 1 71  ? -19.935 -32.137 33.037  1.00 41.55  ? 57  HIS   F N   1 
ATOM   2643 C  CA  . HIS   B 1 71  ? -20.891 -32.332 31.930  1.00 42.29  ? 57  HIS   F CA  1 
ATOM   2644 C  C   . HIS   B 1 71  ? -21.489 -33.721 32.066  1.00 36.50  ? 57  HIS   F C   1 
ATOM   2645 O  O   . HIS   B 1 71  ? -20.768 -34.666 32.386  1.00 43.67  ? 57  HIS   F O   1 
ATOM   2646 C  CB  . HIS   B 1 71  ? -20.138 -32.207 30.590  1.00 38.24  ? 57  HIS   F CB  1 
ATOM   2647 C  CG  . HIS   B 1 71  ? -21.007 -31.873 29.436  1.00 43.10  ? 57  HIS   F CG  1 
ATOM   2648 N  ND1 . HIS   B 1 71  ? -21.818 -32.817 28.846  1.00 39.59  ? 57  HIS   F ND1 1 
ATOM   2649 C  CD2 . HIS   B 1 71  ? -21.165 -30.720 28.745  1.00 41.73  ? 57  HIS   F CD2 1 
ATOM   2650 C  CE1 . HIS   B 1 71  ? -22.458 -32.263 27.847  1.00 42.11  ? 57  HIS   F CE1 1 
ATOM   2651 N  NE2 . HIS   B 1 71  ? -22.069 -30.971 27.755  1.00 41.20  ? 57  HIS   F NE2 1 
ATOM   2652 N  N   . PRO   B 1 72  ? -22.779 -33.912 31.767  1.00 43.17  ? 58  PRO   F N   1 
ATOM   2653 C  CA  . PRO   B 1 72  ? -23.367 -35.251 31.807  1.00 45.46  ? 58  PRO   F CA  1 
ATOM   2654 C  C   . PRO   B 1 72  ? -22.696 -36.256 30.862  1.00 49.71  ? 58  PRO   F C   1 
ATOM   2655 O  O   . PRO   B 1 72  ? -22.727 -37.451 31.140  1.00 45.06  ? 58  PRO   F O   1 
ATOM   2656 C  CB  . PRO   B 1 72  ? -24.828 -35.025 31.416  1.00 46.67  ? 58  PRO   F CB  1 
ATOM   2657 C  CG  . PRO   B 1 72  ? -24.886 -33.646 30.821  1.00 50.69  ? 58  PRO   F CG  1 
ATOM   2658 C  CD  . PRO   B 1 72  ? -23.753 -32.860 31.442  1.00 46.23  ? 58  PRO   F CD  1 
ATOM   2659 N  N   . GLU   B 1 73  ? -22.049 -35.782 29.786  1.00 41.73  ? 59  GLU   F N   1 
ATOM   2660 C  CA  . GLU   B 1 73  ? -21.385 -36.722 28.857  1.00 43.43  ? 59  GLU   F CA  1 
ATOM   2661 C  C   . GLU   B 1 73  ? -20.004 -37.071 29.376  1.00 43.06  ? 59  GLU   F C   1 
ATOM   2662 O  O   . GLU   B 1 73  ? -19.417 -37.936 28.769  1.00 48.59  ? 59  GLU   F O   1 
ATOM   2663 C  CB  . GLU   B 1 73  ? -21.287 -36.162 27.441  1.00 46.31  ? 59  GLU   F CB  1 
ATOM   2664 C  CG  . GLU   B 1 73  ? -22.624 -35.919 26.790  1.00 49.07  ? 59  GLU   F CG  1 
ATOM   2665 C  CD  . GLU   B 1 73  ? -22.470 -35.218 25.450  1.00 49.42  ? 59  GLU   F CD  1 
ATOM   2666 O  OE1 . GLU   B 1 73  ? -21.631 -35.663 24.675  1.00 52.53  ? 59  GLU   F OE1 1 
ATOM   2667 O  OE2 . GLU   B 1 73  ? -23.175 -34.218 25.203  1.00 46.18  ? 59  GLU   F OE2 1 
ATOM   2668 N  N   . GLY   B 1 74  ? -19.517 -36.418 30.430  1.00 39.35  ? 60  GLY   F N   1 
ATOM   2669 C  CA  . GLY   B 1 74  ? -18.208 -36.723 31.035  1.00 41.26  ? 60  GLY   F CA  1 
ATOM   2670 C  C   . GLY   B 1 74  ? -17.491 -35.434 31.393  1.00 44.26  ? 60  GLY   F C   1 
ATOM   2671 O  O   . GLY   B 1 74  ? -17.726 -34.410 30.735  1.00 47.28  ? 60  GLY   F O   1 
ATOM   2672 N  N   . LYS   B 1 75  ? -16.711 -35.474 32.452  1.00 36.97  ? 61  LYS   F N   1 
ATOM   2673 C  CA  . LYS   B 1 75  ? -15.995 -34.322 33.021  1.00 38.49  ? 61  LYS   F CA  1 
ATOM   2674 C  C   . LYS   B 1 75  ? -14.854 -33.908 32.090  1.00 36.45  ? 61  LYS   F C   1 
ATOM   2675 O  O   . LYS   B 1 75  ? -14.041 -34.780 31.671  1.00 38.06  ? 61  LYS   F O   1 
ATOM   2676 C  CB  . LYS   B 1 75  ? -15.537 -34.699 34.420  1.00 43.76  ? 61  LYS   F CB  1 
ATOM   2677 C  CG  . LYS   B 1 75  ? -16.703 -34.798 35.410  1.00 45.89  ? 61  LYS   F CG  1 
ATOM   2678 C  CD  . LYS   B 1 75  ? -16.317 -35.240 36.796  1.00 51.09  ? 61  LYS   F CD  1 
ATOM   2679 C  CE  . LYS   B 1 75  ? -17.455 -35.214 37.814  1.00 51.92  ? 61  LYS   F CE  1 
ATOM   2680 N  NZ  . LYS   B 1 75  ? -18.712 -35.832 37.321  1.00 50.45  ? 61  LYS   F NZ  1 
ATOM   2681 N  N   . ILE   B 1 76  ? -14.783 -32.621 31.822  1.00 37.74  ? 62  ILE   F N   1 
ATOM   2682 C  CA  . ILE   B 1 76  ? -13.740 -32.008 30.954  1.00 38.71  ? 62  ILE   F CA  1 
ATOM   2683 C  C   . ILE   B 1 76  ? -12.952 -31.004 31.797  1.00 38.76  ? 62  ILE   F C   1 
ATOM   2684 O  O   . ILE   B 1 76  ? -13.565 -30.102 32.407  1.00 39.97  ? 62  ILE   F O   1 
ATOM   2685 C  CB  . ILE   B 1 76  ? -14.399 -31.333 29.727  1.00 38.78  ? 62  ILE   F CB  1 
ATOM   2686 C  CG1 . ILE   B 1 76  ? -15.187 -32.331 28.873  1.00 37.33  ? 62  ILE   F CG1 1 
ATOM   2687 C  CG2 . ILE   B 1 76  ? -13.376 -30.586 28.886  1.00 39.22  ? 62  ILE   F CG2 1 
ATOM   2688 C  CD1 . ILE   B 1 76  ? -16.262 -31.661 28.109  1.00 38.65  ? 62  ILE   F CD1 1 
ATOM   2689 N  N   . LEU   B 1 77  ? -11.633 -31.114 31.774  1.00 33.59  ? 63  LEU   F N   1 
ATOM   2690 C  CA  . LEU   B 1 77  ? -10.725 -30.195 32.480  1.00 35.42  ? 63  LEU   F CA  1 
ATOM   2691 C  C   . LEU   B 1 77  ? -9.946  -29.380 31.431  1.00 35.47  ? 63  LEU   F C   1 
ATOM   2692 O  O   . LEU   B 1 77  ? -9.357  -29.998 30.531  1.00 36.29  ? 63  LEU   F O   1 
ATOM   2693 C  CB  . LEU   B 1 77  ? -9.776  -31.039 33.332  1.00 36.56  ? 63  LEU   F CB  1 
ATOM   2694 C  CG  . LEU   B 1 77  ? -8.780  -30.242 34.156  1.00 39.39  ? 63  LEU   F CG  1 
ATOM   2695 C  CD1 . LEU   B 1 77  ? -9.509  -29.347 35.142  1.00 43.75  ? 63  LEU   F CD1 1 
ATOM   2696 C  CD2 . LEU   B 1 77  ? -7.830  -31.166 34.885  1.00 43.52  ? 63  LEU   F CD2 1 
ATOM   2697 N  N   . PHE   B 1 78  ? -9.867  -28.077 31.619  1.00 33.92  ? 64  PHE   F N   1 
ATOM   2698 C  CA  . PHE   B 1 78  ? -9.112  -27.142 30.752  1.00 34.19  ? 64  PHE   F CA  1 
ATOM   2699 C  C   . PHE   B 1 78  ? -7.916  -26.647 31.553  1.00 36.03  ? 64  PHE   F C   1 
ATOM   2700 O  O   . PHE   B 1 78  ? -8.113  -25.941 32.572  1.00 35.64  ? 64  PHE   F O   1 
ATOM   2701 C  CB  . PHE   B 1 78  ? -10.030 -26.047 30.180  1.00 34.90  ? 64  PHE   F CB  1 
ATOM   2702 C  CG  . PHE   B 1 78  ? -9.331  -25.091 29.243  1.00 30.08  ? 64  PHE   F CG  1 
ATOM   2703 C  CD1 . PHE   B 1 78  ? -9.191  -25.392 27.898  1.00 32.79  ? 64  PHE   F CD1 1 
ATOM   2704 C  CD2 . PHE   B 1 78  ? -8.765  -23.913 29.714  1.00 32.61  ? 64  PHE   F CD2 1 
ATOM   2705 C  CE1 . PHE   B 1 78  ? -8.553  -24.518 27.027  1.00 34.08  ? 64  PHE   F CE1 1 
ATOM   2706 C  CE2 . PHE   B 1 78  ? -8.112  -23.039 28.852  1.00 34.89  ? 64  PHE   F CE2 1 
ATOM   2707 C  CZ  . PHE   B 1 78  ? -8.013  -23.342 27.494  1.00 34.07  ? 64  PHE   F CZ  1 
ATOM   2708 N  N   . ASP   B 1 79  ? -6.712  -27.076 31.152  1.00 32.19  ? 65  ASP   F N   1 
ATOM   2709 C  CA  . ASP   B 1 79  ? -5.410  -26.720 31.778  1.00 35.33  ? 65  ASP   F CA  1 
ATOM   2710 C  C   . ASP   B 1 79  ? -5.292  -27.484 33.113  1.00 35.90  ? 65  ASP   F C   1 
ATOM   2711 O  O   . ASP   B 1 79  ? -6.305  -28.113 33.527  1.00 32.76  ? 65  ASP   F O   1 
ATOM   2712 C  CB  . ASP   B 1 79  ? -5.173  -25.198 31.914  1.00 36.75  ? 65  ASP   F CB  1 
ATOM   2713 C  CG  . ASP   B 1 79  ? -4.692  -24.484 30.642  1.00 42.46  ? 65  ASP   F CG  1 
ATOM   2714 O  OD1 . ASP   B 1 79  ? -4.318  -25.209 29.680  1.00 37.73  ? 65  ASP   F OD1 1 
ATOM   2715 O  OD2 . ASP   B 1 79  ? -4.731  -23.197 30.581  1.00 40.91  ? 65  ASP   F OD2 1 
ATOM   2716 N  N   . THR   B 1 80  ? -4.088  -27.492 33.697  1.00 35.48  ? 66  THR   F N   1 
ATOM   2717 C  CA  . THR   B 1 80  ? -3.772  -28.359 34.866  1.00 34.63  ? 66  THR   F CA  1 
ATOM   2718 C  C   . THR   B 1 80  ? -2.864  -27.641 35.859  1.00 35.43  ? 66  THR   F C   1 
ATOM   2719 O  O   . THR   B 1 80  ? -2.406  -28.351 36.786  1.00 38.39  ? 66  THR   F O   1 
ATOM   2720 C  CB  . THR   B 1 80  ? -3.190  -29.714 34.455  1.00 33.81  ? 66  THR   F CB  1 
ATOM   2721 O  OG1 . THR   B 1 80  ? -1.845  -29.504 34.015  1.00 34.52  ? 66  THR   F OG1 1 
ATOM   2722 C  CG2 . THR   B 1 80  ? -4.029  -30.441 33.431  1.00 36.24  ? 66  THR   F CG2 1 
ATOM   2723 N  N   . SER   B 1 81  ? -2.555  -26.354 35.642  1.00 33.29  ? 67  SER   F N   1 
ATOM   2724 C  CA  . SER   B 1 81  ? -1.710  -25.516 36.527  1.00 37.49  ? 67  SER   F CA  1 
ATOM   2725 C  C   . SER   B 1 81  ? -0.293  -26.117 36.656  1.00 39.81  ? 67  SER   F C   1 
ATOM   2726 O  O   . SER   B 1 81  ? 0.206   -26.705 35.645  1.00 39.96  ? 67  SER   F O   1 
ATOM   2727 C  CB  . SER   B 1 81  ? -2.399  -25.260 37.900  1.00 38.97  ? 67  SER   F CB  1 
ATOM   2728 O  OG  . SER   B 1 81  ? -2.483  -26.446 38.665  1.00 37.56  ? 67  SER   F OG  1 
ATOM   2729 N  N   . CYS   B 1 82  ? 0.403   -25.815 37.760  1.00 36.12  ? 68  CYS   F N   1 
ATOM   2730 C  CA  . CYS   B 1 82  ? 1.818   -26.201 38.021  1.00 36.20  ? 68  CYS   F CA  1 
ATOM   2731 C  C   . CYS   B 1 82  ? 1.877   -27.483 38.856  1.00 37.64  ? 68  CYS   F C   1 
ATOM   2732 O  O   . CYS   B 1 82  ? 0.950   -27.779 39.658  1.00 36.83  ? 68  CYS   F O   1 
ATOM   2733 C  CB  . CYS   B 1 82  ? 2.598   -25.102 38.722  1.00 37.15  ? 68  CYS   F CB  1 
ATOM   2734 S  SG  . CYS   B 1 82  ? 2.292   -23.458 38.037  1.00 38.33  ? 68  CYS   F SG  1 
ATOM   2735 N  N   . ASN   B 1 83  ? 2.934   -28.255 38.691  1.00 34.99  ? 69  ASN   F N   1 
ATOM   2736 C  CA  . ASN   B 1 83  ? 3.055   -29.493 39.487  1.00 37.09  ? 69  ASN   F CA  1 
ATOM   2737 C  C   . ASN   B 1 83  ? 3.293   -29.054 40.939  1.00 37.38  ? 69  ASN   F C   1 
ATOM   2738 O  O   . ASN   B 1 83  ? 4.037   -28.111 41.202  1.00 34.23  ? 69  ASN   F O   1 
ATOM   2739 C  CB  . ASN   B 1 83  ? 4.170   -30.411 38.989  1.00 35.79  ? 69  ASN   F CB  1 
ATOM   2740 C  CG  . ASN   B 1 83  ? 4.026   -31.788 39.584  1.00 40.27  ? 69  ASN   F CG  1 
ATOM   2741 O  OD1 . ASN   B 1 83  ? 3.276   -32.664 39.101  1.00 40.55  ? 69  ASN   F OD1 1 
ATOM   2742 N  ND2 . ASN   B 1 83  ? 4.731   -31.950 40.675  1.00 36.91  ? 69  ASN   F ND2 1 
ATOM   2743 N  N   . PRO   B 1 84  ? 2.707   -29.735 41.934  1.00 39.84  ? 70  PRO   F N   1 
ATOM   2744 C  CA  . PRO   B 1 84  ? 3.029   -29.429 43.346  1.00 47.20  ? 70  PRO   F CA  1 
ATOM   2745 C  C   . PRO   B 1 84  ? 4.531   -29.472 43.689  1.00 47.15  ? 70  PRO   F C   1 
ATOM   2746 O  O   . PRO   B 1 84  ? 4.969   -28.839 44.603  1.00 45.31  ? 70  PRO   F O   1 
ATOM   2747 C  CB  . PRO   B 1 84  ? 2.287   -30.523 44.133  1.00 43.08  ? 70  PRO   F CB  1 
ATOM   2748 C  CG  . PRO   B 1 84  ? 1.136   -30.949 43.185  1.00 48.06  ? 70  PRO   F CG  1 
ATOM   2749 C  CD  . PRO   B 1 84  ? 1.725   -30.828 41.782  1.00 43.06  ? 70  PRO   F CD  1 
ATOM   2750 N  N   . ASN   B 1 85  ? 5.336   -30.179 42.902  1.00 45.16  ? 71  ASN   F N   1 
ATOM   2751 C  CA  . ASN   B 1 85  ? 6.782   -30.373 43.190  1.00 45.13  ? 71  ASN   F CA  1 
ATOM   2752 C  C   . ASN   B 1 85  ? 7.634   -29.433 42.345  1.00 42.49  ? 71  ASN   F C   1 
ATOM   2753 O  O   . ASN   B 1 85  ? 8.776   -29.802 42.103  1.00 42.09  ? 71  ASN   F O   1 
ATOM   2754 C  CB  . ASN   B 1 85  ? 7.263   -31.784 42.864  1.00 52.92  ? 71  ASN   F CB  1 
ATOM   2755 C  CG  . ASN   B 1 85  ? 6.421   -32.837 43.533  1.00 61.41  ? 71  ASN   F CG  1 
ATOM   2756 O  OD1 . ASN   B 1 85  ? 5.614   -33.539 42.893  1.00 72.44  ? 71  ASN   F OD1 1 
ATOM   2757 N  ND2 . ASN   B 1 85  ? 6.586   -32.904 44.840  1.00 61.97  ? 71  ASN   F ND2 1 
ATOM   2758 N  N   . SER   B 1 86  ? 7.091   -28.295 41.905  1.00 40.31  ? 72  SER   F N   1 
ATOM   2759 C  CA  . SER   B 1 86  ? 7.757   -27.365 40.952  1.00 40.20  ? 72  SER   F CA  1 
ATOM   2760 C  C   . SER   B 1 86  ? 8.888   -26.609 41.665  1.00 42.95  ? 72  SER   F C   1 
ATOM   2761 O  O   . SER   B 1 86  ? 10.026  -26.544 41.124  1.00 41.39  ? 72  SER   F O   1 
ATOM   2762 C  CB  . SER   B 1 86  ? 6.765   -26.411 40.322  1.00 37.81  ? 72  SER   F CB  1 
ATOM   2763 O  OG  . SER   B 1 86  ? 5.774   -27.118 39.573  1.00 41.91  ? 72  SER   F OG  1 
ATOM   2764 N  N   . MET   B 1 87  ? 8.595   -26.071 42.844  1.00 38.34  ? 73  MET   F N   1 
ATOM   2765 C  CA  . MET   B 1 87  ? 9.415   -25.022 43.479  1.00 39.41  ? 73  MET   F CA  1 
ATOM   2766 C  C   . MET   B 1 87  ? 10.280  -25.677 44.569  1.00 42.02  ? 73  MET   F C   1 
ATOM   2767 O  O   . MET   B 1 87  ? 9.983   -26.792 44.975  1.00 41.35  ? 73  MET   F O   1 
ATOM   2768 C  CB  . MET   B 1 87  ? 8.530   -23.930 44.102  1.00 47.91  ? 73  MET   F CB  1 
ATOM   2769 C  CG  . MET   B 1 87  ? 7.738   -23.084 43.091  1.00 44.31  ? 73  MET   F CG  1 
ATOM   2770 S  SD  . MET   B 1 87  ? 8.759   -21.965 42.132  1.00 41.20  ? 73  MET   F SD  1 
ATOM   2771 C  CE  . MET   B 1 87  ? 9.467   -20.827 43.332  1.00 48.45  ? 73  MET   F CE  1 
ATOM   2772 N  N   . GLY   B 1 88  ? 11.327  -24.995 44.998  1.00 48.10  ? 74  GLY   F N   1 
ATOM   2773 C  CA  . GLY   B 1 88  ? 12.122  -25.411 46.162  1.00 51.29  ? 74  GLY   F CA  1 
ATOM   2774 C  C   . GLY   B 1 88  ? 13.457  -26.009 45.742  1.00 56.95  ? 74  GLY   F C   1 
ATOM   2775 O  O   . GLY   B 1 88  ? 13.688  -26.263 44.563  1.00 51.86  ? 74  GLY   F O   1 
ATOM   2776 N  N   . PRO   B 1 89  ? 14.364  -26.276 46.703  1.00 53.35  ? 75  PRO   F N   1 
ATOM   2777 C  CA  . PRO   B 1 89  ? 15.687  -26.815 46.380  1.00 55.50  ? 75  PRO   F CA  1 
ATOM   2778 C  C   . PRO   B 1 89  ? 15.622  -28.195 45.710  1.00 51.99  ? 75  PRO   F C   1 
ATOM   2779 O  O   . PRO   B 1 89  ? 16.465  -28.443 44.901  1.00 56.28  ? 75  PRO   F O   1 
ATOM   2780 C  CB  . PRO   B 1 89  ? 16.385  -26.917 47.746  1.00 62.06  ? 75  PRO   F CB  1 
ATOM   2781 C  CG  . PRO   B 1 89  ? 15.231  -26.997 48.745  1.00 64.57  ? 75  PRO   F CG  1 
ATOM   2782 C  CD  . PRO   B 1 89  ? 14.127  -26.143 48.147  1.00 57.74  ? 75  PRO   F CD  1 
ATOM   2783 N  N   . GLN   B 1 90  ? 14.608  -29.009 46.032  1.00 55.39  ? 76  GLN   F N   1 
ATOM   2784 C  CA  . GLN   B 1 90  ? 14.323  -30.348 45.424  1.00 59.83  ? 76  GLN   F CA  1 
ATOM   2785 C  C   . GLN   B 1 90  ? 13.273  -30.238 44.295  1.00 52.46  ? 76  GLN   F C   1 
ATOM   2786 O  O   . GLN   B 1 90  ? 12.716  -31.273 43.910  1.00 49.04  ? 76  GLN   F O   1 
ATOM   2787 C  CB  . GLN   B 1 90  ? 13.776  -31.323 46.474  1.00 64.66  ? 76  GLN   F CB  1 
ATOM   2788 C  CG  . GLN   B 1 90  ? 14.848  -32.115 47.211  1.00 75.25  ? 76  GLN   F CG  1 
ATOM   2789 C  CD  . GLN   B 1 90  ? 15.526  -31.293 48.276  1.00 84.08  ? 76  GLN   F CD  1 
ATOM   2790 O  OE1 . GLN   B 1 90  ? 14.937  -30.414 48.901  1.00 94.88  ? 76  GLN   F OE1 1 
ATOM   2791 N  NE2 . GLN   B 1 90  ? 16.790  -31.584 48.503  1.00 95.32  ? 76  GLN   F NE2 1 
ATOM   2792 N  N   . GLY   B 1 91  ? 13.003  -29.030 43.807  1.00 50.50  ? 77  GLY   F N   1 
ATOM   2793 C  CA  . GLY   B 1 91  ? 11.929  -28.763 42.831  1.00 52.75  ? 77  GLY   F CA  1 
ATOM   2794 C  C   . GLY   B 1 91  ? 12.260  -29.261 41.432  1.00 45.30  ? 77  GLY   F C   1 
ATOM   2795 O  O   . GLY   B 1 91  ? 13.441  -29.376 41.112  1.00 44.49  ? 77  GLY   F O   1 
ATOM   2796 N  N   . ARG   B 1 92  ? 11.233  -29.549 40.626  1.00 41.62  ? 78  ARG   F N   1 
ATOM   2797 C  CA  . ARG   B 1 92  ? 11.395  -29.932 39.204  1.00 38.82  ? 78  ARG   F CA  1 
ATOM   2798 C  C   . ARG   B 1 92  ? 11.852  -28.737 38.382  1.00 41.00  ? 78  ARG   F C   1 
ATOM   2799 O  O   . ARG   B 1 92  ? 12.446  -28.953 37.328  1.00 43.87  ? 78  ARG   F O   1 
ATOM   2800 C  CB  . ARG   B 1 92  ? 10.086  -30.484 38.661  1.00 40.19  ? 78  ARG   F CB  1 
ATOM   2801 C  CG  . ARG   B 1 92  ? 9.648   -31.795 39.300  1.00 41.35  ? 78  ARG   F CG  1 
ATOM   2802 C  CD  . ARG   B 1 92  ? 8.416   -32.296 38.614  1.00 38.70  ? 78  ARG   F CD  1 
ATOM   2803 N  NE  . ARG   B 1 92  ? 7.967   -33.598 39.084  1.00 37.15  ? 78  ARG   F NE  1 
ATOM   2804 C  CZ  . ARG   B 1 92  ? 6.901   -34.212 38.631  1.00 42.67  ? 78  ARG   F CZ  1 
ATOM   2805 N  NH1 . ARG   B 1 92  ? 6.163   -33.680 37.652  1.00 39.37  ? 78  ARG   F NH1 1 
ATOM   2806 N  NH2 . ARG   B 1 92  ? 6.564   -35.371 39.158  1.00 40.21  ? 78  ARG   F NH2 1 
ATOM   2807 N  N   . TRP   B 1 93  ? 11.503  -27.521 38.775  1.00 39.45  ? 79  TRP   F N   1 
ATOM   2808 C  CA  . TRP   B 1 93  ? 11.842  -26.340 37.966  1.00 39.71  ? 79  TRP   F CA  1 
ATOM   2809 C  C   . TRP   B 1 93  ? 13.306  -26.010 38.222  1.00 44.38  ? 79  TRP   F C   1 
ATOM   2810 O  O   . TRP   B 1 93  ? 13.692  -25.982 39.381  1.00 44.91  ? 79  TRP   F O   1 
ATOM   2811 C  CB  . TRP   B 1 93  ? 10.934  -25.152 38.282  1.00 39.50  ? 79  TRP   F CB  1 
ATOM   2812 C  CG  . TRP   B 1 93  ? 9.488   -25.278 37.886  1.00 39.40  ? 79  TRP   F CG  1 
ATOM   2813 C  CD1 . TRP   B 1 93  ? 8.831   -26.360 37.363  1.00 38.04  ? 79  TRP   F CD1 1 
ATOM   2814 C  CD2 . TRP   B 1 93  ? 8.498   -24.245 37.999  1.00 38.02  ? 79  TRP   F CD2 1 
ATOM   2815 N  NE1 . TRP   B 1 93  ? 7.501   -26.074 37.162  1.00 38.14  ? 79  TRP   F NE1 1 
ATOM   2816 C  CE2 . TRP   B 1 93  ? 7.277   -24.777 37.524  1.00 34.47  ? 79  TRP   F CE2 1 
ATOM   2817 C  CE3 . TRP   B 1 93  ? 8.530   -22.921 38.448  1.00 40.79  ? 79  TRP   F CE3 1 
ATOM   2818 C  CZ2 . TRP   B 1 93  ? 6.097   -24.042 37.529  1.00 37.31  ? 79  TRP   F CZ2 1 
ATOM   2819 C  CZ3 . TRP   B 1 93  ? 7.372   -22.180 38.412  1.00 39.39  ? 79  TRP   F CZ3 1 
ATOM   2820 C  CH2 . TRP   B 1 93  ? 6.170   -22.741 37.981  1.00 40.53  ? 79  TRP   F CH2 1 
ATOM   2821 N  N   . ALA   B 1 94  ? 14.059  -25.701 37.173  1.00 43.25  ? 80  ALA   F N   1 
ATOM   2822 C  CA  . ALA   B 1 94  ? 15.455  -25.225 37.252  1.00 44.99  ? 80  ALA   F CA  1 
ATOM   2823 C  C   . ALA   B 1 94  ? 15.498  -23.957 38.116  1.00 45.56  ? 80  ALA   F C   1 
ATOM   2824 O  O   . ALA   B 1 94  ? 14.488  -23.218 38.180  1.00 42.26  ? 80  ALA   F O   1 
ATOM   2825 C  CB  . ALA   B 1 94  ? 15.983  -24.955 35.852  1.00 45.93  ? 80  ALA   F CB  1 
ATOM   2826 N  N   . GLU   B 1 95  ? 16.641  -23.683 38.733  1.00 45.66  ? 81  GLU   F N   1 
ATOM   2827 C  CA  . GLU   B 1 95  ? 16.797  -22.569 39.696  1.00 51.79  ? 81  GLU   F CA  1 
ATOM   2828 C  C   . GLU   B 1 95  ? 16.510  -21.248 38.974  1.00 45.83  ? 81  GLU   F C   1 
ATOM   2829 O  O   . GLU   B 1 95  ? 15.791  -20.407 39.571  1.00 48.40  ? 81  GLU   F O   1 
ATOM   2830 C  CB  . GLU   B 1 95  ? 18.172  -22.663 40.379  1.00 58.59  ? 81  GLU   F CB  1 
ATOM   2831 C  CG  . GLU   B 1 95  ? 18.396  -21.638 41.498  1.00 68.37  ? 81  GLU   F CG  1 
ATOM   2832 C  CD  . GLU   B 1 95  ? 17.323  -21.538 42.582  1.00 72.99  ? 81  GLU   F CD  1 
ATOM   2833 O  OE1 . GLU   B 1 95  ? 16.768  -22.590 43.004  1.00 74.90  ? 81  GLU   F OE1 1 
ATOM   2834 O  OE2 . GLU   B 1 95  ? 17.029  -20.401 42.997  1.00 72.30  ? 81  GLU   F OE2 1 
ATOM   2835 N  N   . SER   B 1 96  ? 16.995  -21.064 37.742  1.00 41.20  ? 82  SER   F N   1 
ATOM   2836 C  CA  . SER   B 1 96  ? 16.756  -19.822 36.955  1.00 42.76  ? 82  SER   F CA  1 
ATOM   2837 C  C   . SER   B 1 96  ? 15.242  -19.614 36.733  1.00 44.08  ? 82  SER   F C   1 
ATOM   2838 O  O   . SER   B 1 96  ? 14.762  -18.466 36.826  1.00 42.64  ? 82  SER   F O   1 
ATOM   2839 C  CB  . SER   B 1 96  ? 17.495  -19.838 35.618  1.00 48.37  ? 82  SER   F CB  1 
ATOM   2840 O  OG  . SER   B 1 96  ? 17.081  -20.958 34.836  1.00 44.30  ? 82  SER   F OG  1 
ATOM   2841 N  N   . THR   B 1 97  ? 14.516  -20.686 36.406  1.00 42.76  ? 83  THR   F N   1 
ATOM   2842 C  CA  . THR   B 1 97  ? 13.049  -20.678 36.183  1.00 42.30  ? 83  THR   F CA  1 
ATOM   2843 C  C   . THR   B 1 97  ? 12.333  -20.236 37.475  1.00 46.48  ? 83  THR   F C   1 
ATOM   2844 O  O   . THR   B 1 97  ? 11.477  -19.329 37.431  1.00 41.23  ? 83  THR   F O   1 
ATOM   2845 C  CB  . THR   B 1 97  ? 12.613  -22.070 35.732  1.00 42.83  ? 83  THR   F CB  1 
ATOM   2846 O  OG1 . THR   B 1 97  ? 13.413  -22.414 34.605  1.00 39.58  ? 83  THR   F OG1 1 
ATOM   2847 C  CG2 . THR   B 1 97  ? 11.142  -22.150 35.399  1.00 43.87  ? 83  THR   F CG2 1 
ATOM   2848 N  N   . GLN   B 1 98  ? 12.688  -20.848 38.601  1.00 42.98  ? 84  GLN   F N   1 
ATOM   2849 C  CA  . GLN   B 1 98  ? 12.104  -20.514 39.933  1.00 42.49  ? 84  GLN   F CA  1 
ATOM   2850 C  C   . GLN   B 1 98  ? 12.339  -19.046 40.287  1.00 43.35  ? 84  GLN   F C   1 
ATOM   2851 O  O   . GLN   B 1 98  ? 11.465  -18.452 40.929  1.00 45.07  ? 84  GLN   F O   1 
ATOM   2852 C  CB  . GLN   B 1 98  ? 12.737  -21.378 41.010  1.00 43.05  ? 84  GLN   F CB  1 
ATOM   2853 C  CG  . GLN   B 1 98  ? 12.407  -22.835 40.827  1.00 42.15  ? 84  GLN   F CG  1 
ATOM   2854 C  CD  . GLN   B 1 98  ? 12.669  -23.590 42.103  1.00 47.50  ? 84  GLN   F CD  1 
ATOM   2855 O  OE1 . GLN   B 1 98  ? 12.413  -23.086 43.193  1.00 43.76  ? 84  GLN   F OE1 1 
ATOM   2856 N  NE2 . GLN   B 1 98  ? 13.134  -24.820 41.966  1.00 42.29  ? 84  GLN   F NE2 1 
ATOM   2857 N  N   . GLN   B 1 99  ? 13.437  -18.447 39.836  1.00 45.06  ? 85  GLN   F N   1 
ATOM   2858 C  CA  . GLN   B 1 99  ? 13.769  -17.035 40.167  1.00 46.40  ? 85  GLN   F CA  1 
ATOM   2859 C  C   . GLN   B 1 99  ? 13.062  -16.049 39.214  1.00 46.35  ? 85  GLN   F C   1 
ATOM   2860 O  O   . GLN   B 1 99  ? 12.752  -14.913 39.652  1.00 44.17  ? 85  GLN   F O   1 
ATOM   2861 C  CB  . GLN   B 1 99  ? 15.294  -16.870 40.186  1.00 50.53  ? 85  GLN   F CB  1 
ATOM   2862 C  CG  . GLN   B 1 99  ? 15.942  -17.567 41.384  1.00 63.22  ? 85  GLN   F CG  1 
ATOM   2863 C  CD  . GLN   B 1 99  ? 17.357  -17.106 41.657  1.00 75.46  ? 85  GLN   F CD  1 
ATOM   2864 O  OE1 . GLN   B 1 99  ? 18.257  -17.916 41.873  1.00 88.84  ? 85  GLN   F OE1 1 
ATOM   2865 N  NE2 . GLN   B 1 99  ? 17.569  -15.796 41.665  1.00 83.81  ? 85  GLN   F NE2 1 
ATOM   2866 N  N   . MET   B 1 100 ? 12.805  -16.420 37.959  1.00 43.32  ? 86  MET   F N   1 
ATOM   2867 C  CA  . MET   B 1 100 ? 12.158  -15.492 36.991  1.00 40.83  ? 86  MET   F CA  1 
ATOM   2868 C  C   . MET   B 1 100 ? 10.624  -15.631 37.012  1.00 39.36  ? 86  MET   F C   1 
ATOM   2869 O  O   . MET   B 1 100 ? 9.951   -14.661 36.624  1.00 38.45  ? 86  MET   F O   1 
ATOM   2870 C  CB  . MET   B 1 100 ? 12.632  -15.758 35.554  1.00 42.41  ? 86  MET   F CB  1 
ATOM   2871 C  CG  . MET   B 1 100 ? 13.900  -15.064 35.194  1.00 50.15  ? 86  MET   F CG  1 
ATOM   2872 S  SD  . MET   B 1 100 ? 14.354  -15.332 33.439  1.00 50.23  ? 86  MET   F SD  1 
ATOM   2873 C  CE  . MET   B 1 100 ? 14.809  -17.068 33.422  1.00 51.68  ? 86  MET   F CE  1 
ATOM   2874 N  N   . PHE   B 1 101 ? 10.098  -16.796 37.367  1.00 37.80  ? 87  PHE   F N   1 
ATOM   2875 C  CA  . PHE   B 1 101 ? 8.655   -17.164 37.283  1.00 40.30  ? 87  PHE   F CA  1 
ATOM   2876 C  C   . PHE   B 1 101 ? 8.195   -17.861 38.566  1.00 41.77  ? 87  PHE   F C   1 
ATOM   2877 O  O   . PHE   B 1 101 ? 7.519   -18.879 38.516  1.00 40.98  ? 87  PHE   F O   1 
ATOM   2878 C  CB  . PHE   B 1 101 ? 8.394   -18.098 36.093  1.00 44.08  ? 87  PHE   F CB  1 
ATOM   2879 C  CG  . PHE   B 1 101 ? 8.950   -17.573 34.799  1.00 39.94  ? 87  PHE   F CG  1 
ATOM   2880 C  CD1 . PHE   B 1 101 ? 8.323   -16.544 34.127  1.00 42.80  ? 87  PHE   F CD1 1 
ATOM   2881 C  CD2 . PHE   B 1 101 ? 10.130  -18.089 34.276  1.00 45.53  ? 87  PHE   F CD2 1 
ATOM   2882 C  CE1 . PHE   B 1 101 ? 8.858   -16.051 32.946  1.00 46.44  ? 87  PHE   F CE1 1 
ATOM   2883 C  CE2 . PHE   B 1 101 ? 10.659  -17.599 33.092  1.00 46.80  ? 87  PHE   F CE2 1 
ATOM   2884 C  CZ  . PHE   B 1 101 ? 10.023  -16.574 32.432  1.00 44.44  ? 87  PHE   F CZ  1 
ATOM   2885 N  N   . PRO   B 1 102 ? 8.525   -17.314 39.758  1.00 41.46  ? 88  PRO   F N   1 
ATOM   2886 C  CA  . PRO   B 1 102 ? 8.147   -17.957 41.012  1.00 38.57  ? 88  PRO   F CA  1 
ATOM   2887 C  C   . PRO   B 1 102 ? 6.626   -18.156 41.153  1.00 35.09  ? 88  PRO   F C   1 
ATOM   2888 O  O   . PRO   B 1 102 ? 5.828   -17.238 40.951  1.00 40.65  ? 88  PRO   F O   1 
ATOM   2889 C  CB  . PRO   B 1 102 ? 8.723   -16.996 42.087  1.00 39.79  ? 88  PRO   F CB  1 
ATOM   2890 C  CG  . PRO   B 1 102 ? 8.776   -15.654 41.378  1.00 44.32  ? 88  PRO   F CG  1 
ATOM   2891 C  CD  . PRO   B 1 102 ? 9.199   -16.010 39.951  1.00 41.00  ? 88  PRO   F CD  1 
ATOM   2892 N  N   . TRP   B 1 103 ? 6.252   -19.368 41.536  1.00 34.60  ? 89  TRP   F N   1 
ATOM   2893 C  CA  . TRP   B 1 103 ? 4.865   -19.780 41.803  1.00 36.46  ? 89  TRP   F CA  1 
ATOM   2894 C  C   . TRP   B 1 103 ? 4.661   -19.859 43.327  1.00 44.35  ? 89  TRP   F C   1 
ATOM   2895 O  O   . TRP   B 1 103 ? 5.435   -20.570 43.997  1.00 40.46  ? 89  TRP   F O   1 
ATOM   2896 C  CB  . TRP   B 1 103 ? 4.631   -21.149 41.171  1.00 38.58  ? 89  TRP   F CB  1 
ATOM   2897 C  CG  . TRP   B 1 103 ? 3.249   -21.673 41.332  1.00 36.73  ? 89  TRP   F CG  1 
ATOM   2898 C  CD1 . TRP   B 1 103 ? 2.084   -20.990 41.184  1.00 38.22  ? 89  TRP   F CD1 1 
ATOM   2899 C  CD2 . TRP   B 1 103 ? 2.889   -23.007 41.705  1.00 40.34  ? 89  TRP   F CD2 1 
ATOM   2900 N  NE1 . TRP   B 1 103 ? 1.025   -21.826 41.401  1.00 37.70  ? 89  TRP   F NE1 1 
ATOM   2901 C  CE2 . TRP   B 1 103 ? 1.484   -23.064 41.730  1.00 35.11  ? 89  TRP   F CE2 1 
ATOM   2902 C  CE3 . TRP   B 1 103 ? 3.615   -24.148 42.044  1.00 40.02  ? 89  TRP   F CE3 1 
ATOM   2903 C  CZ2 . TRP   B 1 103 ? 0.786   -24.215 42.065  1.00 40.41  ? 89  TRP   F CZ2 1 
ATOM   2904 C  CZ3 . TRP   B 1 103 ? 2.921   -25.285 42.363  1.00 39.63  ? 89  TRP   F CZ3 1 
ATOM   2905 C  CH2 . TRP   B 1 103 ? 1.526   -25.325 42.352  1.00 37.42  ? 89  TRP   F CH2 1 
ATOM   2906 N  N   . THR   B 1 104 ? 3.631   -19.215 43.840  1.00 40.66  ? 90  THR   F N   1 
ATOM   2907 C  CA  . THR   B 1 104 ? 3.275   -19.303 45.285  1.00 44.21  ? 90  THR   F CA  1 
ATOM   2908 C  C   . THR   B 1 104 ? 1.894   -19.938 45.365  1.00 47.22  ? 90  THR   F C   1 
ATOM   2909 O  O   . THR   B 1 104 ? 0.965   -19.482 44.664  1.00 43.99  ? 90  THR   F O   1 
ATOM   2910 C  CB  . THR   B 1 104 ? 3.375   -17.932 45.963  1.00 48.99  ? 90  THR   F CB  1 
ATOM   2911 O  OG1 . THR   B 1 104 ? 2.376   -17.187 45.299  1.00 50.12  ? 90  THR   F OG1 1 
ATOM   2912 C  CG2 . THR   B 1 104 ? 4.701   -17.226 45.799  1.00 49.61  ? 90  THR   F CG2 1 
ATOM   2913 N  N   . ALA   B 1 105 ? 1.767   -21.005 46.131  1.00 43.44  ? 91  ALA   F N   1 
ATOM   2914 C  CA  . ALA   B 1 105 ? 0.492   -21.725 46.280  1.00 51.20  ? 91  ALA   F CA  1 
ATOM   2915 C  C   . ALA   B 1 105 ? 0.457   -22.387 47.655  1.00 51.06  ? 91  ALA   F C   1 
ATOM   2916 O  O   . ALA   B 1 105 ? 1.406   -23.119 47.958  1.00 45.63  ? 91  ALA   F O   1 
ATOM   2917 C  CB  . ALA   B 1 105 ? 0.362   -22.774 45.197  1.00 51.67  ? 91  ALA   F CB  1 
ATOM   2918 N  N   . THR   B 1 106 ? -0.642  -22.209 48.365  1.00 47.03  ? 92  THR   F N   1 
ATOM   2919 C  CA  . THR   B 1 106 ? -0.989  -23.001 49.575  1.00 54.72  ? 92  THR   F CA  1 
ATOM   2920 C  C   . THR   B 1 106 ? -1.465  -24.387 49.114  1.00 61.11  ? 92  THR   F C   1 
ATOM   2921 O  O   . THR   B 1 106 ? -1.850  -24.534 47.895  1.00 50.60  ? 92  THR   F O   1 
ATOM   2922 C  CB  . THR   B 1 106 ? -2.041  -22.246 50.396  1.00 53.31  ? 92  THR   F CB  1 
ATOM   2923 O  OG1 . THR   B 1 106 ? -3.234  -22.217 49.620  1.00 57.20  ? 92  THR   F OG1 1 
ATOM   2924 C  CG2 . THR   B 1 106 ? -1.622  -20.833 50.752  1.00 52.87  ? 92  THR   F CG2 1 
ATOM   2925 N  N   . GLU   B 1 107 ? -1.467  -25.382 50.010  1.00 47.48  ? 93  GLU   F N   1 
ATOM   2926 C  CA  . GLU   B 1 107 ? -1.896  -26.769 49.662  1.00 54.28  ? 93  GLU   F CA  1 
ATOM   2927 C  C   . GLU   B 1 107 ? -3.323  -26.779 49.100  1.00 52.22  ? 93  GLU   F C   1 
ATOM   2928 O  O   . GLU   B 1 107 ? -3.614  -27.678 48.248  1.00 44.09  ? 93  GLU   F O   1 
ATOM   2929 C  CB  . GLU   B 1 107 ? -1.802  -27.732 50.842  1.00 64.01  ? 93  GLU   F CB  1 
ATOM   2930 C  CG  . GLU   B 1 107 ? -0.451  -28.417 50.873  1.00 79.72  ? 93  GLU   F CG  1 
ATOM   2931 C  CD  . GLU   B 1 107 ? -0.275  -29.452 51.958  1.00 92.04  ? 93  GLU   F CD  1 
ATOM   2932 O  OE1 . GLU   B 1 107 ? -1.090  -29.475 52.914  1.00 105.25 ? 93  GLU   F OE1 1 
ATOM   2933 O  OE2 . GLU   B 1 107 ? 0.672   -30.242 51.818  1.00 102.87 ? 93  GLU   F OE2 1 
ATOM   2934 N  N   . GLU   B 1 108 ? -4.193  -25.862 49.544  1.00 45.38  ? 94  GLU   F N   1 
ATOM   2935 C  CA  . GLU   B 1 108 ? -5.608  -25.843 49.074  1.00 53.92  ? 94  GLU   F CA  1 
ATOM   2936 C  C   . GLU   B 1 108 ? -5.663  -25.416 47.571  1.00 42.34  ? 94  GLU   F C   1 
ATOM   2937 O  O   . GLU   B 1 108 ? -6.650  -25.773 46.900  1.00 40.13  ? 94  GLU   F O   1 
ATOM   2938 C  CB  . GLU   B 1 108 ? -6.483  -25.025 50.042  1.00 63.06  ? 94  GLU   F CB  1 
ATOM   2939 C  CG  . GLU   B 1 108 ? -6.210  -23.527 50.079  1.00 74.51  ? 94  GLU   F CG  1 
ATOM   2940 C  CD  . GLU   B 1 108 ? -7.417  -22.636 50.404  1.00 88.55  ? 94  GLU   F CD  1 
ATOM   2941 O  OE1 . GLU   B 1 108 ? -7.193  -21.505 50.895  1.00 88.68  ? 94  GLU   F OE1 1 
ATOM   2942 O  OE2 . GLU   B 1 108 ? -8.585  -23.039 50.129  1.00 78.89  ? 94  GLU   F OE2 1 
ATOM   2943 N  N   . CYS   B 1 109 ? -4.604  -24.787 47.063  1.00 40.15  ? 95  CYS   F N   1 
ATOM   2944 C  CA  . CYS   B 1 109 ? -4.465  -24.317 45.662  1.00 43.39  ? 95  CYS   F CA  1 
ATOM   2945 C  C   . CYS   B 1 109 ? -4.022  -25.448 44.728  1.00 41.35  ? 95  CYS   F C   1 
ATOM   2946 O  O   . CYS   B 1 109 ? -4.276  -25.296 43.511  1.00 41.46  ? 95  CYS   F O   1 
ATOM   2947 C  CB  . CYS   B 1 109 ? -3.489  -23.160 45.562  1.00 44.06  ? 95  CYS   F CB  1 
ATOM   2948 S  SG  . CYS   B 1 109 ? -4.167  -21.616 46.211  1.00 50.91  ? 95  CYS   F SG  1 
ATOM   2949 N  N   . TYR   B 1 110 ? -3.471  -26.557 45.230  1.00 36.92  ? 96  TYR   F N   1 
ATOM   2950 C  CA  . TYR   B 1 110 ? -3.006  -27.647 44.333  1.00 43.15  ? 96  TYR   F CA  1 
ATOM   2951 C  C   . TYR   B 1 110 ? -4.221  -28.247 43.631  1.00 44.83  ? 96  TYR   F C   1 
ATOM   2952 O  O   . TYR   B 1 110 ? -5.273  -28.401 44.244  1.00 41.29  ? 96  TYR   F O   1 
ATOM   2953 C  CB  . TYR   B 1 110 ? -2.206  -28.755 45.032  1.00 43.69  ? 96  TYR   F CB  1 
ATOM   2954 C  CG  . TYR   B 1 110 ? -0.940  -28.317 45.726  1.00 49.26  ? 96  TYR   F CG  1 
ATOM   2955 C  CD1 . TYR   B 1 110 ? -0.245  -27.191 45.319  1.00 49.31  ? 96  TYR   F CD1 1 
ATOM   2956 C  CD2 . TYR   B 1 110 ? -0.406  -29.072 46.761  1.00 51.73  ? 96  TYR   F CD2 1 
ATOM   2957 C  CE1 . TYR   B 1 110 ? 0.905   -26.780 45.969  1.00 50.29  ? 96  TYR   F CE1 1 
ATOM   2958 C  CE2 . TYR   B 1 110 ? 0.775   -28.705 47.385  1.00 46.68  ? 96  TYR   F CE2 1 
ATOM   2959 C  CZ  . TYR   B 1 110 ? 1.416   -27.549 46.992  1.00 52.06  ? 96  TYR   F CZ  1 
ATOM   2960 O  OH  . TYR   B 1 110 ? 2.562   -27.134 47.565  1.00 50.81  ? 96  TYR   F OH  1 
ATOM   2961 N  N   . LEU   B 1 111 ? -4.075  -28.570 42.349  1.00 40.63  ? 97  LEU   F N   1 
ATOM   2962 C  CA  . LEU   B 1 111 ? -5.232  -29.022 41.537  1.00 40.25  ? 97  LEU   F CA  1 
ATOM   2963 C  C   . LEU   B 1 111 ? -5.858  -30.270 42.169  1.00 39.18  ? 97  LEU   F C   1 
ATOM   2964 O  O   . LEU   B 1 111 ? -7.073  -30.334 42.211  1.00 36.30  ? 97  LEU   F O   1 
ATOM   2965 C  CB  . LEU   B 1 111 ? -4.807  -29.307 40.093  1.00 38.78  ? 97  LEU   F CB  1 
ATOM   2966 C  CG  . LEU   B 1 111 ? -5.910  -29.798 39.156  1.00 38.86  ? 97  LEU   F CG  1 
ATOM   2967 C  CD1 . LEU   B 1 111 ? -6.974  -28.727 38.938  1.00 41.65  ? 97  LEU   F CD1 1 
ATOM   2968 C  CD2 . LEU   B 1 111 ? -5.294  -30.241 37.825  1.00 42.45  ? 97  LEU   F CD2 1 
ATOM   2969 N  N   . HIS   B 1 112 ? -5.071  -31.231 42.655  1.00 39.76  ? 98  HIS   F N   1 
ATOM   2970 C  CA  . HIS   B 1 112 ? -5.671  -32.470 43.219  1.00 41.76  ? 98  HIS   F CA  1 
ATOM   2971 C  C   . HIS   B 1 112 ? -6.574  -32.107 44.428  1.00 36.36  ? 98  HIS   F C   1 
ATOM   2972 O  O   . HIS   B 1 112 ? -7.627  -32.728 44.537  1.00 41.77  ? 98  HIS   F O   1 
ATOM   2973 C  CB  . HIS   B 1 112 ? -4.612  -33.569 43.493  1.00 48.18  ? 98  HIS   F CB  1 
ATOM   2974 C  CG  . HIS   B 1 112 ? -3.786  -33.382 44.717  1.00 65.40  ? 98  HIS   F CG  1 
ATOM   2975 N  ND1 . HIS   B 1 112 ? -2.683  -32.521 44.759  1.00 79.60  ? 98  HIS   F ND1 1 
ATOM   2976 C  CD2 . HIS   B 1 112 ? -3.870  -33.947 45.943  1.00 72.94  ? 98  HIS   F CD2 1 
ATOM   2977 C  CE1 . HIS   B 1 112 ? -2.141  -32.553 45.959  1.00 72.24  ? 98  HIS   F CE1 1 
ATOM   2978 N  NE2 . HIS   B 1 112 ? -2.854  -33.420 46.705  1.00 72.69  ? 98  HIS   F NE2 1 
ATOM   2979 N  N   . ASN   B 1 113 ? -6.195  -31.130 45.250  1.00 39.06  ? 99  ASN   F N   1 
ATOM   2980 C  CA  . ASN   B 1 113 ? -7.036  -30.722 46.413  1.00 43.63  ? 99  ASN   F CA  1 
ATOM   2981 C  C   . ASN   B 1 113 ? -8.267  -29.942 45.922  1.00 47.40  ? 99  ASN   F C   1 
ATOM   2982 O  O   . ASN   B 1 113 ? -9.368  -30.219 46.437  1.00 41.97  ? 99  ASN   F O   1 
ATOM   2983 C  CB  . ASN   B 1 113 ? -6.242  -29.951 47.459  1.00 41.19  ? 99  ASN   F CB  1 
ATOM   2984 C  CG  . ASN   B 1 113 ? -5.158  -30.829 48.053  1.00 47.08  ? 99  ASN   F CG  1 
ATOM   2985 O  OD1 . ASN   B 1 113 ? -5.347  -32.038 48.131  1.00 48.21  ? 99  ASN   F OD1 1 
ATOM   2986 N  ND2 . ASN   B 1 113 ? -4.029  -30.237 48.412  1.00 43.03  ? 99  ASN   F ND2 1 
ATOM   2987 N  N   . ARG   B 1 114 ? -8.115  -29.014 44.966  1.00 42.27  ? 100 ARG   F N   1 
ATOM   2988 C  CA  . ARG   B 1 114 ? -9.283  -28.277 44.414  1.00 40.57  ? 100 ARG   F CA  1 
ATOM   2989 C  C   . ARG   B 1 114 ? -10.296 -29.285 43.885  1.00 38.83  ? 100 ARG   F C   1 
ATOM   2990 O  O   . ARG   B 1 114 ? -11.490 -29.117 44.133  1.00 38.89  ? 100 ARG   F O   1 
ATOM   2991 C  CB  . ARG   B 1 114 ? -8.840  -27.307 43.318  1.00 40.95  ? 100 ARG   F CB  1 
ATOM   2992 C  CG  . ARG   B 1 114 ? -8.074  -26.107 43.830  1.00 39.04  ? 100 ARG   F CG  1 
ATOM   2993 C  CD  . ARG   B 1 114 ? -8.953  -25.207 44.712  1.00 40.15  ? 100 ARG   F CD  1 
ATOM   2994 N  NE  . ARG   B 1 114 ? -8.239  -23.966 45.013  1.00 38.55  ? 100 ARG   F NE  1 
ATOM   2995 C  CZ  . ARG   B 1 114 ? -8.436  -23.212 46.090  1.00 39.68  ? 100 ARG   F CZ  1 
ATOM   2996 N  NH1 . ARG   B 1 114 ? -9.356  -23.561 46.975  1.00 40.52  ? 100 ARG   F NH1 1 
ATOM   2997 N  NH2 . ARG   B 1 114 ? -7.751  -22.103 46.247  1.00 40.54  ? 100 ARG   F NH2 1 
ATOM   2998 N  N   . LEU   B 1 115 ? -9.855  -30.336 43.183  1.00 41.29  ? 101 LEU   F N   1 
ATOM   2999 C  CA  . LEU   B 1 115 ? -10.799 -31.330 42.599  1.00 37.35  ? 101 LEU   F CA  1 
ATOM   3000 C  C   . LEU   B 1 115 ? -11.418 -32.180 43.743  1.00 38.54  ? 101 LEU   F C   1 
ATOM   3001 O  O   . LEU   B 1 115 ? -12.623 -32.499 43.672  1.00 39.27  ? 101 LEU   F O   1 
ATOM   3002 C  CB  . LEU   B 1 115 ? -10.064 -32.231 41.599  1.00 40.56  ? 101 LEU   F CB  1 
ATOM   3003 C  CG  . LEU   B 1 115 ? -9.699  -31.566 40.263  1.00 38.17  ? 101 LEU   F CG  1 
ATOM   3004 C  CD1 . LEU   B 1 115 ? -8.794  -32.482 39.454  1.00 39.24  ? 101 LEU   F CD1 1 
ATOM   3005 C  CD2 . LEU   B 1 115 ? -10.941 -31.231 39.477  1.00 38.07  ? 101 LEU   F CD2 1 
ATOM   3006 N  N   . GLU   B 1 116 ? -10.615 -32.577 44.725  1.00 38.93  ? 102 GLU   F N   1 
ATOM   3007 C  CA  . GLU   B 1 116 ? -11.094 -33.418 45.868  1.00 46.78  ? 102 GLU   F CA  1 
ATOM   3008 C  C   . GLU   B 1 116 ? -12.228 -32.655 46.601  1.00 41.57  ? 102 GLU   F C   1 
ATOM   3009 O  O   . GLU   B 1 116 ? -13.250 -33.273 46.915  1.00 41.69  ? 102 GLU   F O   1 
ATOM   3010 C  CB  . GLU   B 1 116 ? -9.916  -33.750 46.792  1.00 49.22  ? 102 GLU   F CB  1 
ATOM   3011 C  CG  . GLU   B 1 116 ? -10.306 -34.493 48.067  1.00 53.87  ? 102 GLU   F CG  1 
ATOM   3012 C  CD  . GLU   B 1 116 ? -9.125  -34.940 48.924  1.00 75.31  ? 102 GLU   F CD  1 
ATOM   3013 O  OE1 . GLU   B 1 116 ? -8.045  -34.267 48.896  1.00 79.29  ? 102 GLU   F OE1 1 
ATOM   3014 O  OE2 . GLU   B 1 116 ? -9.275  -35.974 49.619  1.00 91.01  ? 102 GLU   F OE2 1 
ATOM   3015 N  N   . GLN   B 1 117 ? -12.101 -31.333 46.758  1.00 43.12  ? 103 GLN   F N   1 
ATOM   3016 C  CA  . GLN   B 1 117 ? -13.123 -30.488 47.424  1.00 41.61  ? 103 GLN   F CA  1 
ATOM   3017 C  C   . GLN   B 1 117 ? -14.407 -30.494 46.611  1.00 45.42  ? 103 GLN   F C   1 
ATOM   3018 O  O   . GLN   B 1 117 ? -15.452 -30.203 47.188  1.00 46.80  ? 103 GLN   F O   1 
ATOM   3019 C  CB  . GLN   B 1 117 ? -12.572 -29.092 47.690  1.00 44.87  ? 103 GLN   F CB  1 
ATOM   3020 C  CG  . GLN   B 1 117 ? -11.655 -29.063 48.902  1.00 44.17  ? 103 GLN   F CG  1 
ATOM   3021 C  CD  . GLN   B 1 117 ? -12.326 -29.642 50.138  1.00 55.20  ? 103 GLN   F CD  1 
ATOM   3022 O  OE1 . GLN   B 1 117 ? -11.925 -30.685 50.634  1.00 57.97  ? 103 GLN   F OE1 1 
ATOM   3023 N  NE2 . GLN   B 1 117 ? -13.352 -28.980 50.654  1.00 53.13  ? 103 GLN   F NE2 1 
ATOM   3024 N  N   . LEU   B 1 118 ? -14.361 -30.847 45.330  1.00 39.61  ? 104 LEU   F N   1 
ATOM   3025 C  CA  . LEU   B 1 118 ? -15.580 -30.968 44.497  1.00 39.19  ? 104 LEU   F CA  1 
ATOM   3026 C  C   . LEU   B 1 118 ? -16.005 -32.432 44.411  1.00 37.16  ? 104 LEU   F C   1 
ATOM   3027 O  O   . LEU   B 1 118 ? -16.955 -32.738 43.639  1.00 41.82  ? 104 LEU   F O   1 
ATOM   3028 C  CB  . LEU   B 1 118 ? -15.304 -30.371 43.113  1.00 38.43  ? 104 LEU   F CB  1 
ATOM   3029 C  CG  . LEU   B 1 118 ? -14.896 -28.899 43.094  1.00 38.50  ? 104 LEU   F CG  1 
ATOM   3030 C  CD1 . LEU   B 1 118 ? -14.586 -28.430 41.667  1.00 39.49  ? 104 LEU   F CD1 1 
ATOM   3031 C  CD2 . LEU   B 1 118 ? -16.016 -28.043 43.680  1.00 40.75  ? 104 LEU   F CD2 1 
ATOM   3032 N  N   . LYS   B 1 119 ? -15.364 -33.310 45.178  1.00 41.81  ? 105 LYS   F N   1 
ATOM   3033 C  CA  . LYS   B 1 119 ? -15.648 -34.783 45.146  1.00 47.79  ? 105 LYS   F CA  1 
ATOM   3034 C  C   . LYS   B 1 119 ? -15.288 -35.355 43.758  1.00 40.78  ? 105 LYS   F C   1 
ATOM   3035 O  O   . LYS   B 1 119 ? -15.978 -36.240 43.258  1.00 38.45  ? 105 LYS   F O   1 
ATOM   3036 C  CB  . LYS   B 1 119 ? -17.095 -35.122 45.547  1.00 54.63  ? 105 LYS   F CB  1 
ATOM   3037 C  CG  . LYS   B 1 119 ? -17.513 -34.702 46.967  1.00 68.30  ? 105 LYS   F CG  1 
ATOM   3038 C  CD  . LYS   B 1 119 ? -18.334 -33.383 47.045  1.00 90.66  ? 105 LYS   F CD  1 
ATOM   3039 C  CE  . LYS   B 1 119 ? -19.583 -33.430 47.919  1.00 92.91  ? 105 LYS   F CE  1 
ATOM   3040 N  NZ  . LYS   B 1 119 ? -20.724 -34.075 47.227  1.00 99.49  ? 105 LYS   F NZ  1 
ATOM   3041 N  N   . VAL   B 1 120 ? -14.234 -34.846 43.139  1.00 40.94  ? 106 VAL   F N   1 
ATOM   3042 C  CA  . VAL   B 1 120 ? -13.809 -35.278 41.772  1.00 42.34  ? 106 VAL   F CA  1 
ATOM   3043 C  C   . VAL   B 1 120 ? -12.428 -35.885 41.940  1.00 41.76  ? 106 VAL   F C   1 
ATOM   3044 O  O   . VAL   B 1 120 ? -11.524 -35.172 42.445  1.00 45.26  ? 106 VAL   F O   1 
ATOM   3045 C  CB  . VAL   B 1 120 ? -13.779 -34.106 40.769  1.00 42.95  ? 106 VAL   F CB  1 
ATOM   3046 C  CG1 . VAL   B 1 120 ? -13.211 -34.542 39.408  1.00 42.49  ? 106 VAL   F CG1 1 
ATOM   3047 C  CG2 . VAL   B 1 120 ? -15.158 -33.489 40.595  1.00 45.19  ? 106 VAL   F CG2 1 
ATOM   3048 N  N   . ARG   B 1 121 ? -12.329 -37.187 41.690  1.00 43.25  ? 107 ARG   F N   1 
ATOM   3049 C  CA  . ARG   B 1 121 ? -11.018 -37.888 41.718  1.00 52.07  ? 107 ARG   F CA  1 
ATOM   3050 C  C   . ARG   B 1 121 ? -10.403 -37.732 40.320  1.00 46.56  ? 107 ARG   F C   1 
ATOM   3051 O  O   . ARG   B 1 121 ? -11.123 -37.716 39.333  1.00 41.75  ? 107 ARG   F O   1 
ATOM   3052 C  CB  . ARG   B 1 121 ? -11.135 -39.400 41.934  1.00 54.98  ? 107 ARG   F CB  1 
ATOM   3053 C  CG  . ARG   B 1 121 ? -11.763 -39.878 43.235  1.00 64.73  ? 107 ARG   F CG  1 
ATOM   3054 C  CD  . ARG   B 1 121 ? -13.070 -40.549 42.857  1.00 74.17  ? 107 ARG   F CD  1 
ATOM   3055 N  NE  . ARG   B 1 121 ? -12.982 -41.997 42.866  1.00 79.99  ? 107 ARG   F NE  1 
ATOM   3056 C  CZ  . ARG   B 1 121 ? -13.720 -42.818 42.121  1.00 83.64  ? 107 ARG   F CZ  1 
ATOM   3057 N  NH1 . ARG   B 1 121 ? -14.610 -42.346 41.267  1.00 69.50  ? 107 ARG   F NH1 1 
ATOM   3058 N  NH2 . ARG   B 1 121 ? -13.559 -44.126 42.234  1.00 88.11  ? 107 ARG   F NH2 1 
ATOM   3059 N  N   . PRO   B 1 122 ? -9.068  -37.750 40.167  1.00 47.74  ? 108 PRO   F N   1 
ATOM   3060 C  CA  . PRO   B 1 122 ? -8.424  -37.714 38.847  1.00 48.99  ? 108 PRO   F CA  1 
ATOM   3061 C  C   . PRO   B 1 122 ? -9.013  -38.706 37.841  1.00 48.35  ? 108 PRO   F C   1 
ATOM   3062 O  O   . PRO   B 1 122 ? -9.208  -38.346 36.707  1.00 43.52  ? 108 PRO   F O   1 
ATOM   3063 C  CB  . PRO   B 1 122 ? -6.979  -38.090 39.163  1.00 48.12  ? 108 PRO   F CB  1 
ATOM   3064 C  CG  . PRO   B 1 122 ? -6.772  -37.547 40.570  1.00 54.98  ? 108 PRO   F CG  1 
ATOM   3065 C  CD  . PRO   B 1 122 ? -8.086  -37.810 41.264  1.00 48.44  ? 108 PRO   F CD  1 
ATOM   3066 N  N   . GLU   B 1 123 ? -9.336  -39.920 38.293  1.00 44.91  ? 109 GLU   F N   1 
ATOM   3067 C  CA  . GLU   B 1 123 ? -9.868  -40.980 37.397  1.00 46.08  ? 109 GLU   F CA  1 
ATOM   3068 C  C   . GLU   B 1 123 ? -11.245 -40.612 36.848  1.00 44.09  ? 109 GLU   F C   1 
ATOM   3069 O  O   . GLU   B 1 123 ? -11.696 -41.302 35.936  1.00 41.56  ? 109 GLU   F O   1 
ATOM   3070 C  CB  . GLU   B 1 123 ? -9.947  -42.322 38.120  1.00 55.53  ? 109 GLU   F CB  1 
ATOM   3071 C  CG  . GLU   B 1 123 ? -11.035 -42.380 39.170  1.00 63.57  ? 109 GLU   F CG  1 
ATOM   3072 C  CD  . GLU   B 1 123 ? -10.853 -43.582 40.070  1.00 74.34  ? 109 GLU   F CD  1 
ATOM   3073 O  OE1 . GLU   B 1 123 ? -11.232 -44.695 39.651  1.00 78.39  ? 109 GLU   F OE1 1 
ATOM   3074 O  OE2 . GLU   B 1 123 ? -10.278 -43.400 41.153  1.00 79.04  ? 109 GLU   F OE2 1 
ATOM   3075 N  N   . ASP   B 1 124 ? -11.950 -39.634 37.429  1.00 46.94  ? 110 ASP   F N   1 
ATOM   3076 C  CA  . ASP   B 1 124 ? -13.298 -39.232 36.932  1.00 47.64  ? 110 ASP   F CA  1 
ATOM   3077 C  C   . ASP   B 1 124 ? -13.169 -38.283 35.721  1.00 40.24  ? 110 ASP   F C   1 
ATOM   3078 O  O   . ASP   B 1 124 ? -14.201 -37.929 35.172  1.00 41.26  ? 110 ASP   F O   1 
ATOM   3079 C  CB  . ASP   B 1 124 ? -14.162 -38.585 38.033  1.00 46.48  ? 110 ASP   F CB  1 
ATOM   3080 C  CG  . ASP   B 1 124 ? -14.359 -39.465 39.270  1.00 56.98  ? 110 ASP   F CG  1 
ATOM   3081 O  OD1 . ASP   B 1 124 ? -14.517 -40.705 39.087  1.00 51.98  ? 110 ASP   F OD1 1 
ATOM   3082 O  OD2 . ASP   B 1 124 ? -14.303 -38.910 40.397  1.00 55.34  ? 110 ASP   F OD2 1 
ATOM   3083 N  N   . ILE   B 1 125 ? -11.975 -37.848 35.347  1.00 41.06  ? 111 ILE   F N   1 
ATOM   3084 C  CA  . ILE   B 1 125 ? -11.808 -36.900 34.186  1.00 42.26  ? 111 ILE   F CA  1 
ATOM   3085 C  C   . ILE   B 1 125 ? -11.766 -37.711 32.895  1.00 37.11  ? 111 ILE   F C   1 
ATOM   3086 O  O   . ILE   B 1 125 ? -10.889 -38.555 32.748  1.00 44.27  ? 111 ILE   F O   1 
ATOM   3087 C  CB  . ILE   B 1 125 ? -10.600 -35.962 34.356  1.00 40.94  ? 111 ILE   F CB  1 
ATOM   3088 C  CG1 . ILE   B 1 125 ? -10.601 -35.253 35.717  1.00 39.09  ? 111 ILE   F CG1 1 
ATOM   3089 C  CG2 . ILE   B 1 125 ? -10.507 -34.947 33.215  1.00 42.68  ? 111 ILE   F CG2 1 
ATOM   3090 C  CD1 . ILE   B 1 125 ? -11.795 -34.385 35.971  1.00 37.60  ? 111 ILE   F CD1 1 
ATOM   3091 N  N   . ARG   B 1 126 ? -12.722 -37.478 32.012  1.00 39.08  ? 112 ARG   F N   1 
ATOM   3092 C  CA  . ARG   B 1 126 ? -12.790 -38.119 30.673  1.00 41.29  ? 112 ARG   F CA  1 
ATOM   3093 C  C   . ARG   B 1 126 ? -11.852 -37.403 29.679  1.00 40.91  ? 112 ARG   F C   1 
ATOM   3094 O  O   . ARG   B 1 126 ? -11.184 -38.109 28.932  1.00 37.79  ? 112 ARG   F O   1 
ATOM   3095 C  CB  . ARG   B 1 126 ? -14.208 -38.056 30.137  1.00 40.70  ? 112 ARG   F CB  1 
ATOM   3096 C  CG  . ARG   B 1 126 ? -14.419 -38.844 28.857  1.00 46.38  ? 112 ARG   F CG  1 
ATOM   3097 C  CD  . ARG   B 1 126 ? -15.825 -38.660 28.294  1.00 49.68  ? 112 ARG   F CD  1 
ATOM   3098 N  NE  . ARG   B 1 126 ? -16.022 -39.442 27.080  1.00 57.77  ? 112 ARG   F NE  1 
ATOM   3099 C  CZ  . ARG   B 1 126 ? -16.996 -39.272 26.193  1.00 57.32  ? 112 ARG   F CZ  1 
ATOM   3100 N  NH1 . ARG   B 1 126 ? -17.909 -38.335 26.355  1.00 60.42  ? 112 ARG   F NH1 1 
ATOM   3101 N  NH2 . ARG   B 1 126 ? -17.054 -40.049 25.129  1.00 59.24  ? 112 ARG   F NH2 1 
ATOM   3102 N  N   . TYR   B 1 127 ? -11.822 -36.064 29.674  1.00 36.70  ? 113 TYR   F N   1 
ATOM   3103 C  CA  . TYR   B 1 127 ? -10.939 -35.261 28.781  1.00 38.97  ? 113 TYR   F CA  1 
ATOM   3104 C  C   . TYR   B 1 127 ? -10.180 -34.182 29.543  1.00 36.96  ? 113 TYR   F C   1 
ATOM   3105 O  O   . TYR   B 1 127 ? -10.746 -33.457 30.358  1.00 34.12  ? 113 TYR   F O   1 
ATOM   3106 C  CB  . TYR   B 1 127 ? -11.756 -34.564 27.690  1.00 35.97  ? 113 TYR   F CB  1 
ATOM   3107 C  CG  . TYR   B 1 127 ? -12.478 -35.489 26.755  1.00 37.74  ? 113 TYR   F CG  1 
ATOM   3108 C  CD1 . TYR   B 1 127 ? -11.763 -36.334 25.921  1.00 44.18  ? 113 TYR   F CD1 1 
ATOM   3109 C  CD2 . TYR   B 1 127 ? -13.859 -35.519 26.679  1.00 40.80  ? 113 TYR   F CD2 1 
ATOM   3110 C  CE1 . TYR   B 1 127 ? -12.404 -37.167 25.010  1.00 44.23  ? 113 TYR   F CE1 1 
ATOM   3111 C  CE2 . TYR   B 1 127 ? -14.520 -36.371 25.808  1.00 43.31  ? 113 TYR   F CE2 1 
ATOM   3112 C  CZ  . TYR   B 1 127 ? -13.787 -37.185 24.962  1.00 46.15  ? 113 TYR   F CZ  1 
ATOM   3113 O  OH  . TYR   B 1 127 ? -14.417 -37.976 24.058  1.00 52.37  ? 113 TYR   F OH  1 
ATOM   3114 N  N   . VAL   B 1 128 ? -8.913  -34.033 29.188  1.00 34.38  ? 114 VAL   F N   1 
ATOM   3115 C  CA  . VAL   B 1 128 ? -8.075  -32.879 29.595  1.00 35.01  ? 114 VAL   F CA  1 
ATOM   3116 C  C   . VAL   B 1 128 ? -7.706  -32.148 28.310  1.00 35.52  ? 114 VAL   F C   1 
ATOM   3117 O  O   . VAL   B 1 128 ? -7.206  -32.840 27.386  1.00 36.28  ? 114 VAL   F O   1 
ATOM   3118 C  CB  . VAL   B 1 128 ? -6.823  -33.317 30.353  1.00 36.10  ? 114 VAL   F CB  1 
ATOM   3119 C  CG1 . VAL   B 1 128 ? -6.037  -32.103 30.810  1.00 38.56  ? 114 VAL   F CG1 1 
ATOM   3120 C  CG2 . VAL   B 1 128 ? -7.154  -34.216 31.523  1.00 40.85  ? 114 VAL   F CG2 1 
ATOM   3121 N  N   . VAL   B 1 129 ? -8.092  -30.888 28.210  1.00 30.80  ? 115 VAL   F N   1 
ATOM   3122 C  CA  . VAL   B 1 129 ? -7.659  -29.991 27.104  1.00 33.86  ? 115 VAL   F CA  1 
ATOM   3123 C  C   . VAL   B 1 129 ? -6.438  -29.223 27.605  1.00 34.24  ? 115 VAL   F C   1 
ATOM   3124 O  O   . VAL   B 1 129 ? -6.573  -28.412 28.505  1.00 33.09  ? 115 VAL   F O   1 
ATOM   3125 C  CB  . VAL   B 1 129 ? -8.803  -29.090 26.605  1.00 32.99  ? 115 VAL   F CB  1 
ATOM   3126 C  CG1 . VAL   B 1 129 ? -8.281  -28.154 25.515  1.00 33.90  ? 115 VAL   F CG1 1 
ATOM   3127 C  CG2 . VAL   B 1 129 ? -9.981  -29.931 26.119  1.00 37.89  ? 115 VAL   F CG2 1 
ATOM   3128 N  N   . ALA   B 1 130 ? -5.253  -29.507 27.061  1.00 35.18  ? 116 ALA   F N   1 
ATOM   3129 C  CA  . ALA   B 1 130 ? -4.015  -28.765 27.355  1.00 35.05  ? 116 ALA   F CA  1 
ATOM   3130 C  C   . ALA   B 1 130 ? -3.954  -27.579 26.402  1.00 38.36  ? 116 ALA   F C   1 
ATOM   3131 O  O   . ALA   B 1 130 ? -3.688  -27.832 25.202  1.00 35.55  ? 116 ALA   F O   1 
ATOM   3132 C  CB  . ALA   B 1 130 ? -2.826  -29.668 27.171  1.00 34.54  ? 116 ALA   F CB  1 
ATOM   3133 N  N   . SER   B 1 131 ? -4.181  -26.359 26.889  1.00 34.64  ? 117 SER   F N   1 
ATOM   3134 C  CA  . SER   B 1 131 ? -4.126  -25.140 26.053  1.00 35.21  ? 117 SER   F CA  1 
ATOM   3135 C  C   . SER   B 1 131 ? -2.781  -25.170 25.286  1.00 33.15  ? 117 SER   F C   1 
ATOM   3136 O  O   . SER   B 1 131 ? -2.719  -24.820 24.096  1.00 33.23  ? 117 SER   F O   1 
ATOM   3137 C  CB  . SER   B 1 131 ? -4.375  -23.851 26.886  1.00 37.36  ? 117 SER   F CB  1 
ATOM   3138 O  OG  . SER   B 1 131 ? -3.304  -23.528 27.778  1.00 35.18  ? 117 SER   F OG  1 
ATOM   3139 N  N   . HIS   B 1 132 ? -1.737  -25.559 26.009  1.00 30.94  ? 118 HIS   F N   1 
ATOM   3140 C  CA  . HIS   B 1 132 ? -0.331  -25.678 25.578  1.00 32.74  ? 118 HIS   F CA  1 
ATOM   3141 C  C   . HIS   B 1 132 ? 0.443   -26.370 26.702  1.00 34.61  ? 118 HIS   F C   1 
ATOM   3142 O  O   . HIS   B 1 132 ? -0.184  -26.786 27.701  1.00 32.07  ? 118 HIS   F O   1 
ATOM   3143 C  CB  . HIS   B 1 132 ? 0.268   -24.350 25.112  1.00 31.87  ? 118 HIS   F CB  1 
ATOM   3144 C  CG  . HIS   B 1 132 ? 0.403   -23.299 26.138  1.00 31.32  ? 118 HIS   F CG  1 
ATOM   3145 N  ND1 . HIS   B 1 132 ? -0.663  -22.845 26.886  1.00 34.03  ? 118 HIS   F ND1 1 
ATOM   3146 C  CD2 . HIS   B 1 132 ? 1.455   -22.516 26.464  1.00 32.15  ? 118 HIS   F CD2 1 
ATOM   3147 C  CE1 . HIS   B 1 132 ? -0.244  -21.871 27.681  1.00 35.91  ? 118 HIS   F CE1 1 
ATOM   3148 N  NE2 . HIS   B 1 132 ? 1.050   -21.656 27.452  1.00 29.62  ? 118 HIS   F NE2 1 
ATOM   3149 N  N   . LEU   B 1 133 ? 1.734   -26.566 26.537  1.00 32.05  ? 119 LEU   F N   1 
ATOM   3150 C  CA  . LEU   B 1 133 ? 2.468   -27.465 27.475  1.00 30.96  ? 119 LEU   F CA  1 
ATOM   3151 C  C   . LEU   B 1 133 ? 3.502   -26.700 28.303  1.00 29.16  ? 119 LEU   F C   1 
ATOM   3152 O  O   . LEU   B 1 133 ? 4.427   -27.337 28.828  1.00 32.46  ? 119 LEU   F O   1 
ATOM   3153 C  CB  . LEU   B 1 133 ? 3.094   -28.570 26.627  1.00 30.63  ? 119 LEU   F CB  1 
ATOM   3154 C  CG  . LEU   B 1 133 ? 2.093   -29.546 26.018  1.00 29.46  ? 119 LEU   F CG  1 
ATOM   3155 C  CD1 . LEU   B 1 133 ? 2.789   -30.638 25.224  1.00 32.86  ? 119 LEU   F CD1 1 
ATOM   3156 C  CD2 . LEU   B 1 133 ? 1.151   -30.139 27.032  1.00 31.44  ? 119 LEU   F CD2 1 
ATOM   3157 N  N   . HIS   B 1 134 ? 3.325   -25.393 28.468  1.00 30.81  ? 120 HIS   F N   1 
ATOM   3158 C  CA  . HIS   B 1 134 ? 4.122   -24.549 29.389  1.00 32.16  ? 120 HIS   F CA  1 
ATOM   3159 C  C   . HIS   B 1 134 ? 3.938   -25.027 30.839  1.00 33.25  ? 120 HIS   F C   1 
ATOM   3160 O  O   . HIS   B 1 134 ? 2.906   -25.621 31.138  1.00 32.40  ? 120 HIS   F O   1 
ATOM   3161 C  CB  . HIS   B 1 134 ? 3.755   -23.070 29.251  1.00 32.38  ? 120 HIS   F CB  1 
ATOM   3162 C  CG  . HIS   B 1 134 ? 4.437   -22.358 28.149  1.00 30.62  ? 120 HIS   F CG  1 
ATOM   3163 N  ND1 . HIS   B 1 134 ? 3.968   -21.155 27.647  1.00 33.97  ? 120 HIS   F ND1 1 
ATOM   3164 C  CD2 . HIS   B 1 134 ? 5.532   -22.690 27.419  1.00 35.18  ? 120 HIS   F CD2 1 
ATOM   3165 C  CE1 . HIS   B 1 134 ? 4.813   -20.748 26.682  1.00 32.05  ? 120 HIS   F CE1 1 
ATOM   3166 N  NE2 . HIS   B 1 134 ? 5.772   -21.669 26.541  1.00 32.91  ? 120 HIS   F NE2 1 
ATOM   3167 N  N   . LEU   B 1 135 ? 4.921   -24.704 31.684  1.00 31.88  ? 121 LEU   F N   1 
ATOM   3168 C  CA  . LEU   B 1 135 ? 5.066   -25.145 33.091  1.00 36.54  ? 121 LEU   F CA  1 
ATOM   3169 C  C   . LEU   B 1 135 ? 3.811   -24.803 33.903  1.00 35.94  ? 121 LEU   F C   1 
ATOM   3170 O  O   . LEU   B 1 135 ? 3.516   -25.564 34.833  1.00 34.70  ? 121 LEU   F O   1 
ATOM   3171 C  CB  . LEU   B 1 135 ? 6.337   -24.522 33.685  1.00 36.28  ? 121 LEU   F CB  1 
ATOM   3172 C  CG  . LEU   B 1 135 ? 6.382   -23.029 33.986  1.00 38.45  ? 121 LEU   F CG  1 
ATOM   3173 C  CD1 . LEU   B 1 135 ? 7.740   -22.676 34.625  1.00 39.65  ? 121 LEU   F CD1 1 
ATOM   3174 C  CD2 . LEU   B 1 135 ? 6.152   -22.158 32.765  1.00 41.14  ? 121 LEU   F CD2 1 
ATOM   3175 N  N   . ASP   B 1 136 ? 3.116   -23.703 33.576  1.00 36.75  ? 122 ASP   F N   1 
ATOM   3176 C  CA  . ASP   B 1 136 ? 1.967   -23.187 34.366  1.00 36.34  ? 122 ASP   F CA  1 
ATOM   3177 C  C   . ASP   B 1 136 ? 0.632   -23.691 33.805  1.00 38.21  ? 122 ASP   F C   1 
ATOM   3178 O  O   . ASP   B 1 136 ? -0.405  -23.279 34.371  1.00 36.72  ? 122 ASP   F O   1 
ATOM   3179 C  CB  . ASP   B 1 136 ? 2.010   -21.656 34.449  1.00 38.88  ? 122 ASP   F CB  1 
ATOM   3180 C  CG  . ASP   B 1 136 ? 2.021   -21.005 33.079  1.00 40.27  ? 122 ASP   F CG  1 
ATOM   3181 O  OD1 . ASP   B 1 136 ? 2.761   -21.495 32.185  1.00 36.00  ? 122 ASP   F OD1 1 
ATOM   3182 O  OD2 . ASP   B 1 136 ? 1.311   -20.019 32.921  1.00 41.81  ? 122 ASP   F OD2 1 
ATOM   3183 N  N   . HIS   B 1 137 ? 0.626   -24.598 32.821  1.00 33.06  ? 123 HIS   F N   1 
ATOM   3184 C  CA  . HIS   B 1 137 ? -0.606  -25.167 32.225  1.00 30.91  ? 123 HIS   F CA  1 
ATOM   3185 C  C   . HIS   B 1 137 ? -0.586  -26.691 32.210  1.00 31.78  ? 123 HIS   F C   1 
ATOM   3186 O  O   . HIS   B 1 137 ? -1.701  -27.288 32.236  1.00 31.53  ? 123 HIS   F O   1 
ATOM   3187 C  CB  . HIS   B 1 137 ? -0.922  -24.556 30.830  1.00 32.90  ? 123 HIS   F CB  1 
ATOM   3188 C  CG  . HIS   B 1 137 ? -1.024  -23.070 30.859  1.00 33.22  ? 123 HIS   F CG  1 
ATOM   3189 N  ND1 . HIS   B 1 137 ? -2.247  -22.427 30.910  1.00 34.95  ? 123 HIS   F ND1 1 
ATOM   3190 C  CD2 . HIS   B 1 137 ? -0.062  -22.102 30.910  1.00 34.09  ? 123 HIS   F CD2 1 
ATOM   3191 C  CE1 . HIS   B 1 137 ? -2.046  -21.128 30.997  1.00 32.99  ? 123 HIS   F CE1 1 
ATOM   3192 N  NE2 . HIS   B 1 137 ? -0.697  -20.884 31.007  1.00 31.99  ? 123 HIS   F NE2 1 
ATOM   3193 N  N   . ALA   B 1 138 ? 0.585   -27.339 32.122  1.00 35.96  ? 124 ALA   F N   1 
ATOM   3194 C  CA  . ALA   B 1 138 ? 0.678   -28.805 31.885  1.00 37.16  ? 124 ALA   F CA  1 
ATOM   3195 C  C   . ALA   B 1 138 ? 1.269   -29.502 33.129  1.00 37.79  ? 124 ALA   F C   1 
ATOM   3196 O  O   . ALA   B 1 138 ? 1.512   -30.700 33.047  1.00 34.65  ? 124 ALA   F O   1 
ATOM   3197 C  CB  . ALA   B 1 138 ? 1.527   -29.095 30.645  1.00 36.34  ? 124 ALA   F CB  1 
ATOM   3198 N  N   . GLY   B 1 139 ? 1.487   -28.771 34.227  1.00 37.21  ? 125 GLY   F N   1 
ATOM   3199 C  CA  . GLY   B 1 139 ? 2.107   -29.277 35.471  1.00 38.96  ? 125 GLY   F CA  1 
ATOM   3200 C  C   . GLY   B 1 139 ? 1.491   -30.536 36.081  1.00 38.99  ? 125 GLY   F C   1 
ATOM   3201 O  O   . GLY   B 1 139 ? 2.283   -31.393 36.602  1.00 40.65  ? 125 GLY   F O   1 
ATOM   3202 N  N   . CYS   B 1 140 ? 0.178   -30.754 35.976  1.00 35.44  ? 126 CYS   F N   1 
ATOM   3203 C  CA  . CYS   B 1 140 ? -0.459  -31.944 36.592  1.00 37.76  ? 126 CYS   F CA  1 
ATOM   3204 C  C   . CYS   B 1 140 ? -1.081  -32.870 35.577  1.00 35.36  ? 126 CYS   F C   1 
ATOM   3205 O  O   . CYS   B 1 140 ? -1.908  -33.732 35.988  1.00 36.73  ? 126 CYS   F O   1 
ATOM   3206 C  CB  . CYS   B 1 140 ? -1.490  -31.569 37.660  1.00 40.68  ? 126 CYS   F CB  1 
ATOM   3207 S  SG  . CYS   B 1 140 ? -0.823  -30.448 38.907  1.00 41.31  ? 126 CYS   F SG  1 
ATOM   3208 N  N   . LEU   B 1 141 ? -0.697  -32.800 34.299  1.00 36.07  ? 127 LEU   F N   1 
ATOM   3209 C  CA  . LEU   B 1 141 ? -1.220  -33.800 33.340  1.00 31.44  ? 127 LEU   F CA  1 
ATOM   3210 C  C   . LEU   B 1 141 ? -1.001  -35.232 33.844  1.00 31.69  ? 127 LEU   F C   1 
ATOM   3211 O  O   . LEU   B 1 141 ? -1.834  -36.085 33.570  1.00 34.39  ? 127 LEU   F O   1 
ATOM   3212 C  CB  . LEU   B 1 141 ? -0.531  -33.646 31.971  1.00 36.07  ? 127 LEU   F CB  1 
ATOM   3213 C  CG  . LEU   B 1 141 ? -0.929  -32.428 31.142  1.00 38.42  ? 127 LEU   F CG  1 
ATOM   3214 C  CD1 . LEU   B 1 141 ? -0.062  -32.388 29.875  1.00 44.11  ? 127 LEU   F CD1 1 
ATOM   3215 C  CD2 . LEU   B 1 141 ? -2.415  -32.452 30.790  1.00 39.35  ? 127 LEU   F CD2 1 
ATOM   3216 N  N   . GLU   B 1 142 ? 0.128   -35.506 34.475  1.00 37.69  ? 128 GLU   F N   1 
ATOM   3217 C  CA  . GLU   B 1 142 ? 0.503   -36.885 34.903  1.00 41.56  ? 128 GLU   F CA  1 
ATOM   3218 C  C   . GLU   B 1 142 ? -0.557  -37.532 35.818  1.00 40.08  ? 128 GLU   F C   1 
ATOM   3219 O  O   . GLU   B 1 142 ? -0.590  -38.759 35.850  1.00 39.18  ? 128 GLU   F O   1 
ATOM   3220 C  CB  . GLU   B 1 142 ? 1.866   -36.915 35.604  1.00 42.84  ? 128 GLU   F CB  1 
ATOM   3221 C  CG  . GLU   B 1 142 ? 1.902   -36.164 36.910  1.00 43.23  ? 128 GLU   F CG  1 
ATOM   3222 C  CD  . GLU   B 1 142 ? 3.329   -35.857 37.319  1.00 46.82  ? 128 GLU   F CD  1 
ATOM   3223 O  OE1 . GLU   B 1 142 ? 3.840   -36.495 38.259  1.00 48.56  ? 128 GLU   F OE1 1 
ATOM   3224 O  OE2 . GLU   B 1 142 ? 3.899   -34.940 36.749  1.00 48.07  ? 128 GLU   F OE2 1 
ATOM   3225 N  N   . MET   B 1 143 ? -1.402  -36.759 36.502  1.00 42.35  ? 129 MET   F N   1 
ATOM   3226 C  CA  . MET   B 1 143 ? -2.513  -37.308 37.338  1.00 44.20  ? 129 MET   F CA  1 
ATOM   3227 C  C   . MET   B 1 143 ? -3.561  -38.031 36.490  1.00 43.51  ? 129 MET   F C   1 
ATOM   3228 O  O   . MET   B 1 143 ? -4.264  -38.903 37.048  1.00 39.65  ? 129 MET   F O   1 
ATOM   3229 C  CB  . MET   B 1 143 ? -3.246  -36.190 38.092  1.00 48.76  ? 129 MET   F CB  1 
ATOM   3230 C  CG  . MET   B 1 143 ? -2.481  -35.584 39.266  1.00 53.93  ? 129 MET   F CG  1 
ATOM   3231 S  SD  . MET   B 1 143 ? -3.302  -34.051 39.854  1.00 56.89  ? 129 MET   F SD  1 
ATOM   3232 C  CE  . MET   B 1 143 ? -5.010  -34.570 39.931  1.00 64.96  ? 129 MET   F CE  1 
ATOM   3233 N  N   . PHE   B 1 144 ? -3.783  -37.645 35.228  1.00 39.62  ? 130 PHE   F N   1 
ATOM   3234 C  CA  . PHE   B 1 144 ? -5.039  -37.996 34.515  1.00 38.65  ? 130 PHE   F CA  1 
ATOM   3235 C  C   . PHE   B 1 144 ? -4.808  -39.214 33.611  1.00 43.52  ? 130 PHE   F C   1 
ATOM   3236 O  O   . PHE   B 1 144 ? -4.949  -39.145 32.365  1.00 39.35  ? 130 PHE   F O   1 
ATOM   3237 C  CB  . PHE   B 1 144 ? -5.624  -36.751 33.857  1.00 38.57  ? 130 PHE   F CB  1 
ATOM   3238 C  CG  . PHE   B 1 144 ? -5.849  -35.639 34.837  1.00 38.25  ? 130 PHE   F CG  1 
ATOM   3239 C  CD1 . PHE   B 1 144 ? -6.882  -35.717 35.767  1.00 38.99  ? 130 PHE   F CD1 1 
ATOM   3240 C  CD2 . PHE   B 1 144 ? -4.987  -34.559 34.891  1.00 36.40  ? 130 PHE   F CD2 1 
ATOM   3241 C  CE1 . PHE   B 1 144 ? -7.054  -34.723 36.708  1.00 37.34  ? 130 PHE   F CE1 1 
ATOM   3242 C  CE2 . PHE   B 1 144 ? -5.158  -33.580 35.853  1.00 40.75  ? 130 PHE   F CE2 1 
ATOM   3243 C  CZ  . PHE   B 1 144 ? -6.194  -33.663 36.753  1.00 38.04  ? 130 PHE   F CZ  1 
ATOM   3244 N  N   . THR   B 1 145 ? -4.579  -40.360 34.246  1.00 38.94  ? 131 THR   F N   1 
ATOM   3245 C  CA  . THR   B 1 145 ? -4.245  -41.650 33.593  1.00 40.87  ? 131 THR   F CA  1 
ATOM   3246 C  C   . THR   B 1 145 ? -5.489  -42.312 33.023  1.00 42.19  ? 131 THR   F C   1 
ATOM   3247 O  O   . THR   B 1 145 ? -5.328  -43.293 32.275  1.00 41.51  ? 131 THR   F O   1 
ATOM   3248 C  CB  . THR   B 1 145 ? -3.505  -42.571 34.569  1.00 42.45  ? 131 THR   F CB  1 
ATOM   3249 O  OG1 . THR   B 1 145 ? -4.271  -42.588 35.771  1.00 43.82  ? 131 THR   F OG1 1 
ATOM   3250 C  CG2 . THR   B 1 145 ? -2.107  -42.103 34.877  1.00 44.42  ? 131 THR   F CG2 1 
ATOM   3251 N  N   . ASN   B 1 146 ? -6.686  -41.790 33.297  1.00 41.10  ? 132 ASN   F N   1 
ATOM   3252 C  CA  . ASN   B 1 146 ? -7.930  -42.395 32.779  1.00 44.76  ? 132 ASN   F CA  1 
ATOM   3253 C  C   . ASN   B 1 146 ? -8.551  -41.479 31.713  1.00 45.66  ? 132 ASN   F C   1 
ATOM   3254 O  O   . ASN   B 1 146 ? -9.615  -41.834 31.187  1.00 44.54  ? 132 ASN   F O   1 
ATOM   3255 C  CB  . ASN   B 1 146 ? -8.858  -42.725 33.958  1.00 54.15  ? 132 ASN   F CB  1 
ATOM   3256 C  CG  . ASN   B 1 146 ? -9.908  -43.775 33.652  1.00 57.27  ? 132 ASN   F CG  1 
ATOM   3257 O  OD1 . ASN   B 1 146 ? -11.002 -43.719 34.213  1.00 63.52  ? 132 ASN   F OD1 1 
ATOM   3258 N  ND2 . ASN   B 1 146 ? -9.635  -44.698 32.743  1.00 57.99  ? 132 ASN   F ND2 1 
ATOM   3259 N  N   . ALA   B 1 147 ? -7.922  -40.337 31.417  1.00 41.57  ? 133 ALA   F N   1 
ATOM   3260 C  CA  . ALA   B 1 147 ? -8.436  -39.338 30.456  1.00 40.69  ? 133 ALA   F CA  1 
ATOM   3261 C  C   . ALA   B 1 147 ? -7.787  -39.545 29.070  1.00 40.35  ? 133 ALA   F C   1 
ATOM   3262 O  O   . ALA   B 1 147 ? -6.696  -40.210 28.959  1.00 38.73  ? 133 ALA   F O   1 
ATOM   3263 C  CB  . ALA   B 1 147 ? -8.204  -37.948 31.009  1.00 40.21  ? 133 ALA   F CB  1 
ATOM   3264 N  N   . THR   B 1 148 ? -8.427  -38.972 28.047  1.00 41.37  ? 134 THR   F N   1 
ATOM   3265 C  CA  . THR   B 1 148 ? -7.784  -38.589 26.757  1.00 38.44  ? 134 THR   F CA  1 
ATOM   3266 C  C   . THR   B 1 148 ? -7.239  -37.165 26.905  1.00 37.27  ? 134 THR   F C   1 
ATOM   3267 O  O   . THR   B 1 148 ? -7.992  -36.314 27.308  1.00 33.74  ? 134 THR   F O   1 
ATOM   3268 C  CB  . THR   B 1 148 ? -8.739  -38.678 25.579  1.00 40.35  ? 134 THR   F CB  1 
ATOM   3269 O  OG1 . THR   B 1 148 ? -9.265  -40.000 25.629  1.00 37.72  ? 134 THR   F OG1 1 
ATOM   3270 C  CG2 . THR   B 1 148 ? -8.073  -38.396 24.244  1.00 43.98  ? 134 THR   F CG2 1 
ATOM   3271 N  N   . ILE   B 1 149 ? -5.936  -36.992 26.709  1.00 33.26  ? 135 ILE   F N   1 
ATOM   3272 C  CA  . ILE   B 1 149 ? -5.252  -35.687 26.768  1.00 32.52  ? 135 ILE   F CA  1 
ATOM   3273 C  C   . ILE   B 1 149 ? -5.263  -35.106 25.363  1.00 35.02  ? 135 ILE   F C   1 
ATOM   3274 O  O   . ILE   B 1 149 ? -4.593  -35.666 24.497  1.00 34.14  ? 135 ILE   F O   1 
ATOM   3275 C  CB  . ILE   B 1 149 ? -3.833  -35.786 27.305  1.00 36.34  ? 135 ILE   F CB  1 
ATOM   3276 C  CG1 . ILE   B 1 149 ? -3.757  -36.631 28.586  1.00 36.07  ? 135 ILE   F CG1 1 
ATOM   3277 C  CG2 . ILE   B 1 149 ? -3.306  -34.371 27.506  1.00 35.93  ? 135 ILE   F CG2 1 
ATOM   3278 C  CD1 . ILE   B 1 149 ? -4.600  -36.110 29.740  1.00 36.78  ? 135 ILE   F CD1 1 
ATOM   3279 N  N   . ILE   B 1 150 ? -6.010  -34.021 25.201  1.00 32.08  ? 136 ILE   F N   1 
ATOM   3280 C  CA  . ILE   B 1 150 ? -6.142  -33.277 23.933  1.00 32.38  ? 136 ILE   F CA  1 
ATOM   3281 C  C   . ILE   B 1 150 ? -5.103  -32.155 23.919  1.00 34.23  ? 136 ILE   F C   1 
ATOM   3282 O  O   . ILE   B 1 150 ? -5.103  -31.274 24.803  1.00 34.20  ? 136 ILE   F O   1 
ATOM   3283 C  CB  . ILE   B 1 150 ? -7.576  -32.811 23.716  1.00 35.55  ? 136 ILE   F CB  1 
ATOM   3284 C  CG1 . ILE   B 1 150 ? -8.539  -34.011 23.766  1.00 37.67  ? 136 ILE   F CG1 1 
ATOM   3285 C  CG2 . ILE   B 1 150 ? -7.654  -32.070 22.395  1.00 34.34  ? 136 ILE   F CG2 1 
ATOM   3286 C  CD1 . ILE   B 1 150 ? -9.964  -33.624 23.788  1.00 43.48  ? 136 ILE   F CD1 1 
ATOM   3287 N  N   . VAL   B 1 151 ? -4.233  -32.195 22.914  1.00 30.63  ? 137 VAL   F N   1 
ATOM   3288 C  CA  . VAL   B 1 151 ? -3.117  -31.234 22.817  1.00 30.34  ? 137 VAL   F CA  1 
ATOM   3289 C  C   . VAL   B 1 151 ? -2.882  -30.958 21.338  1.00 32.61  ? 137 VAL   F C   1 
ATOM   3290 O  O   . VAL   B 1 151 ? -3.094  -31.861 20.529  1.00 30.72  ? 137 VAL   F O   1 
ATOM   3291 C  CB  . VAL   B 1 151 ? -1.860  -31.785 23.511  1.00 30.92  ? 137 VAL   F CB  1 
ATOM   3292 C  CG1 . VAL   B 1 151 ? -1.320  -33.018 22.800  1.00 34.62  ? 137 VAL   F CG1 1 
ATOM   3293 C  CG2 . VAL   B 1 151 ? -0.803  -30.726 23.660  1.00 33.11  ? 137 VAL   F CG2 1 
ATOM   3294 N  N   . HIS   B 1 152 ? -2.390  -29.761 21.020  1.00 30.51  ? 138 HIS   F N   1 
ATOM   3295 C  CA  . HIS   B 1 152 ? -1.977  -29.434 19.636  1.00 30.29  ? 138 HIS   F CA  1 
ATOM   3296 C  C   . HIS   B 1 152 ? -0.772  -30.295 19.242  1.00 30.91  ? 138 HIS   F C   1 
ATOM   3297 O  O   . HIS   B 1 152 ? 0.221   -30.339 19.962  1.00 29.13  ? 138 HIS   F O   1 
ATOM   3298 C  CB  . HIS   B 1 152 ? -1.705  -27.940 19.498  1.00 31.06  ? 138 HIS   F CB  1 
ATOM   3299 C  CG  . HIS   B 1 152 ? -1.757  -27.512 18.078  1.00 31.10  ? 138 HIS   F CG  1 
ATOM   3300 N  ND1 . HIS   B 1 152 ? -0.718  -27.800 17.194  1.00 32.09  ? 138 HIS   F ND1 1 
ATOM   3301 C  CD2 . HIS   B 1 152 ? -2.706  -26.849 17.386  1.00 34.77  ? 138 HIS   F CD2 1 
ATOM   3302 C  CE1 . HIS   B 1 152 ? -1.033  -27.339 15.995  1.00 35.55  ? 138 HIS   F CE1 1 
ATOM   3303 N  NE2 . HIS   B 1 152 ? -2.257  -26.710 16.082  1.00 32.88  ? 138 HIS   F NE2 1 
ATOM   3304 N  N   . GLU   B 1 153 ? -0.810  -30.896 18.066  1.00 31.68  ? 139 GLU   F N   1 
ATOM   3305 C  CA  . GLU   B 1 153 ? 0.296   -31.767 17.579  1.00 32.20  ? 139 GLU   F CA  1 
ATOM   3306 C  C   . GLU   B 1 153 ? 1.625   -30.998 17.560  1.00 29.88  ? 139 GLU   F C   1 
ATOM   3307 O  O   . GLU   B 1 153 ? 2.637   -31.590 17.920  1.00 29.57  ? 139 GLU   F O   1 
ATOM   3308 C  CB  . GLU   B 1 153 ? -0.068  -32.413 16.238  1.00 35.81  ? 139 GLU   F CB  1 
ATOM   3309 C  CG  . GLU   B 1 153 ? 0.280   -31.618 15.004  1.00 40.53  ? 139 GLU   F CG  1 
ATOM   3310 C  CD  . GLU   B 1 153 ? -0.071  -32.362 13.711  1.00 47.08  ? 139 GLU   F CD  1 
ATOM   3311 O  OE1 . GLU   B 1 153 ? 0.004   -33.606 13.803  1.00 43.31  ? 139 GLU   F OE1 1 
ATOM   3312 O  OE2 . GLU   B 1 153 ? -0.478  -31.703 12.622  1.00 37.36  ? 139 GLU   F OE2 1 
ATOM   3313 N  N   . ASP   B 1 154 ? 1.644   -29.725 17.191  1.00 28.82  ? 140 ASP   F N   1 
ATOM   3314 C  CA  . ASP   B 1 154 ? 2.915   -28.963 17.079  1.00 31.05  ? 140 ASP   F CA  1 
ATOM   3315 C  C   . ASP   B 1 154 ? 3.439   -28.663 18.496  1.00 31.95  ? 140 ASP   F C   1 
ATOM   3316 O  O   . ASP   B 1 154 ? 4.663   -28.614 18.709  1.00 30.01  ? 140 ASP   F O   1 
ATOM   3317 C  CB  . ASP   B 1 154 ? 2.763   -27.704 16.233  1.00 31.52  ? 140 ASP   F CB  1 
ATOM   3318 C  CG  . ASP   B 1 154 ? 2.490   -27.986 14.763  1.00 32.10  ? 140 ASP   F CG  1 
ATOM   3319 O  OD1 . ASP   B 1 154 ? 3.098   -28.934 14.227  1.00 34.05  ? 140 ASP   F OD1 1 
ATOM   3320 O  OD2 . ASP   B 1 154 ? 1.606   -27.313 14.179  1.00 34.34  ? 140 ASP   F OD2 1 
ATOM   3321 N  N   . GLU   B 1 155 ? 2.539   -28.476 19.452  1.00 31.24  ? 141 GLU   F N   1 
ATOM   3322 C  CA  . GLU   B 1 155 ? 2.944   -28.221 20.850  1.00 28.36  ? 141 GLU   F CA  1 
ATOM   3323 C  C   . GLU   B 1 155 ? 3.573   -29.492 21.430  1.00 29.34  ? 141 GLU   F C   1 
ATOM   3324 O  O   . GLU   B 1 155 ? 4.625   -29.413 22.075  1.00 30.87  ? 141 GLU   F O   1 
ATOM   3325 C  CB  . GLU   B 1 155 ? 1.756   -27.712 21.629  1.00 26.90  ? 141 GLU   F CB  1 
ATOM   3326 C  CG  . GLU   B 1 155 ? 2.119   -27.285 23.019  1.00 29.93  ? 141 GLU   F CG  1 
ATOM   3327 C  CD  . GLU   B 1 155 ? 2.897   -25.984 23.099  1.00 33.69  ? 141 GLU   F CD  1 
ATOM   3328 O  OE1 . GLU   B 1 155 ? 3.098   -25.343 22.023  1.00 30.89  ? 141 GLU   F OE1 1 
ATOM   3329 O  OE2 . GLU   B 1 155 ? 3.261   -25.585 24.241  1.00 33.19  ? 141 GLU   F OE2 1 
ATOM   3330 N  N   . PHE   B 1 156 ? 2.943   -30.615 21.192  1.00 30.20  ? 142 PHE   F N   1 
ATOM   3331 C  CA  . PHE   B 1 156 ? 3.423   -31.932 21.659  1.00 31.35  ? 142 PHE   F CA  1 
ATOM   3332 C  C   . PHE   B 1 156 ? 4.794   -32.189 21.051  1.00 32.27  ? 142 PHE   F C   1 
ATOM   3333 O  O   . PHE   B 1 156 ? 5.715   -32.515 21.770  1.00 31.46  ? 142 PHE   F O   1 
ATOM   3334 C  CB  . PHE   B 1 156 ? 2.390   -32.990 21.311  1.00 33.14  ? 142 PHE   F CB  1 
ATOM   3335 C  CG  . PHE   B 1 156 ? 2.556   -34.339 21.955  1.00 31.98  ? 142 PHE   F CG  1 
ATOM   3336 C  CD1 . PHE   B 1 156 ? 2.761   -34.439 23.325  1.00 35.65  ? 142 PHE   F CD1 1 
ATOM   3337 C  CD2 . PHE   B 1 156 ? 2.330   -35.494 21.234  1.00 33.59  ? 142 PHE   F CD2 1 
ATOM   3338 C  CE1 . PHE   B 1 156 ? 2.837   -35.678 23.941  1.00 38.78  ? 142 PHE   F CE1 1 
ATOM   3339 C  CE2 . PHE   B 1 156 ? 2.417   -36.734 21.852  1.00 35.46  ? 142 PHE   F CE2 1 
ATOM   3340 C  CZ  . PHE   B 1 156 ? 2.628   -36.818 23.208  1.00 34.13  ? 142 PHE   F CZ  1 
ATOM   3341 N  N   . ASN   B 1 157 ? 4.958   -31.966 19.744  1.00 30.35  ? 143 ASN   F N   1 
ATOM   3342 C  CA  . ASN   B 1 157 ? 6.246   -32.236 19.068  1.00 29.79  ? 143 ASN   F CA  1 
ATOM   3343 C  C   . ASN   B 1 157 ? 7.347   -31.395 19.702  1.00 33.33  ? 143 ASN   F C   1 
ATOM   3344 O  O   . ASN   B 1 157 ? 8.466   -31.947 19.949  1.00 31.47  ? 143 ASN   F O   1 
ATOM   3345 C  CB  . ASN   B 1 157 ? 6.145   -32.046 17.561  1.00 30.72  ? 143 ASN   F CB  1 
ATOM   3346 C  CG  . ASN   B 1 157 ? 5.301   -33.112 16.899  1.00 31.93  ? 143 ASN   F CG  1 
ATOM   3347 O  OD1 . ASN   B 1 157 ? 4.997   -34.149 17.476  1.00 34.10  ? 143 ASN   F OD1 1 
ATOM   3348 N  ND2 . ASN   B 1 157 ? 4.886   -32.858 15.671  1.00 37.01  ? 143 ASN   F ND2 1 
ATOM   3349 N  N   . GLY   B 1 158 ? 7.072   -30.106 19.904  1.00 30.75  ? 144 GLY   F N   1 
ATOM   3350 C  CA  . GLY   B 1 158 ? 8.055   -29.153 20.426  1.00 30.26  ? 144 GLY   F CA  1 
ATOM   3351 C  C   . GLY   B 1 158 ? 8.454   -29.548 21.841  1.00 31.94  ? 144 GLY   F C   1 
ATOM   3352 O  O   . GLY   B 1 158 ? 9.673   -29.551 22.180  1.00 33.43  ? 144 GLY   F O   1 
ATOM   3353 N  N   . ALA   B 1 159 ? 7.495   -29.915 22.663  1.00 32.25  ? 145 ALA   F N   1 
ATOM   3354 C  CA  . ALA   B 1 159 ? 7.805   -30.294 24.063  1.00 33.55  ? 145 ALA   F CA  1 
ATOM   3355 C  C   . ALA   B 1 159 ? 8.646   -31.593 24.043  1.00 31.34  ? 145 ALA   F C   1 
ATOM   3356 O  O   . ALA   B 1 159 ? 9.595   -31.717 24.787  1.00 32.40  ? 145 ALA   F O   1 
ATOM   3357 C  CB  . ALA   B 1 159 ? 6.527   -30.445 24.844  1.00 33.52  ? 145 ALA   F CB  1 
ATOM   3358 N  N   . LEU   B 1 160 ? 8.252   -32.564 23.254  1.00 29.58  ? 146 LEU   F N   1 
ATOM   3359 C  CA  . LEU   B 1 160 ? 8.991   -33.843 23.194  1.00 32.59  ? 146 LEU   F CA  1 
ATOM   3360 C  C   . LEU   B 1 160 ? 10.424  -33.599 22.684  1.00 33.75  ? 146 LEU   F C   1 
ATOM   3361 O  O   . LEU   B 1 160 ? 11.334  -34.300 23.148  1.00 32.03  ? 146 LEU   F O   1 
ATOM   3362 C  CB  . LEU   B 1 160 ? 8.236   -34.863 22.328  1.00 31.50  ? 146 LEU   F CB  1 
ATOM   3363 C  CG  . LEU   B 1 160 ? 6.906   -35.383 22.841  1.00 31.41  ? 146 LEU   F CG  1 
ATOM   3364 C  CD1 . LEU   B 1 160 ? 6.267   -36.341 21.851  1.00 31.30  ? 146 LEU   F CD1 1 
ATOM   3365 C  CD2 . LEU   B 1 160 ? 7.052   -36.080 24.181  1.00 36.33  ? 146 LEU   F CD2 1 
ATOM   3366 N  N   . GLN   B 1 161 ? 10.678  -32.643 21.784  1.00 34.32  ? 147 GLN   F N   1 
ATOM   3367 C  CA  . GLN   B 1 161 ? 12.073  -32.335 21.375  1.00 34.57  ? 147 GLN   F CA  1 
ATOM   3368 C  C   . GLN   B 1 161 ? 12.833  -31.725 22.573  1.00 34.75  ? 147 GLN   F C   1 
ATOM   3369 O  O   . GLN   B 1 161 ? 14.030  -32.007 22.748  1.00 33.85  ? 147 GLN   F O   1 
ATOM   3370 C  CB  . GLN   B 1 161 ? 12.140  -31.408 20.155  1.00 32.72  ? 147 GLN   F CB  1 
ATOM   3371 C  CG  . GLN   B 1 161 ? 11.843  -32.079 18.813  1.00 34.74  ? 147 GLN   F CG  1 
ATOM   3372 C  CD  . GLN   B 1 161 ? 12.383  -31.247 17.672  1.00 38.16  ? 147 GLN   F CD  1 
ATOM   3373 O  OE1 . GLN   B 1 161 ? 13.379  -30.543 17.825  1.00 37.06  ? 147 GLN   F OE1 1 
ATOM   3374 N  NE2 . GLN   B 1 161 ? 11.696  -31.265 16.538  1.00 35.13  ? 147 GLN   F NE2 1 
ATOM   3375 N  N   . CYS   B 1 162 ? 12.210  -30.881 23.381  1.00 33.63  ? 148 CYS   F N   1 
ATOM   3376 C  CA  . CYS   B 1 162 ? 12.892  -30.307 24.579  1.00 35.73  ? 148 CYS   F CA  1 
ATOM   3377 C  C   . CYS   B 1 162 ? 13.349  -31.471 25.471  1.00 36.35  ? 148 CYS   F C   1 
ATOM   3378 O  O   . CYS   B 1 162 ? 14.462  -31.406 25.940  1.00 39.92  ? 148 CYS   F O   1 
ATOM   3379 C  CB  . CYS   B 1 162 ? 11.992  -29.386 25.378  1.00 37.78  ? 148 CYS   F CB  1 
ATOM   3380 S  SG  . CYS   B 1 162 ? 11.649  -27.833 24.527  1.00 40.97  ? 148 CYS   F SG  1 
ATOM   3381 N  N   . TYR   B 1 163 ? 12.499  -32.491 25.625  1.00 34.90  ? 149 TYR   F N   1 
ATOM   3382 C  CA  . TYR   B 1 163 ? 12.746  -33.695 26.456  1.00 37.28  ? 149 TYR   F CA  1 
ATOM   3383 C  C   . TYR   B 1 163 ? 13.913  -34.493 25.867  1.00 36.54  ? 149 TYR   F C   1 
ATOM   3384 O  O   . TYR   B 1 163 ? 14.888  -34.828 26.593  1.00 39.40  ? 149 TYR   F O   1 
ATOM   3385 C  CB  . TYR   B 1 163 ? 11.511  -34.585 26.551  1.00 37.36  ? 149 TYR   F CB  1 
ATOM   3386 C  CG  . TYR   B 1 163 ? 11.695  -35.825 27.391  1.00 36.59  ? 149 TYR   F CG  1 
ATOM   3387 C  CD1 . TYR   B 1 163 ? 11.718  -35.741 28.777  1.00 40.20  ? 149 TYR   F CD1 1 
ATOM   3388 C  CD2 . TYR   B 1 163 ? 11.855  -37.074 26.815  1.00 39.91  ? 149 TYR   F CD2 1 
ATOM   3389 C  CE1 . TYR   B 1 163 ? 11.929  -36.858 29.567  1.00 40.15  ? 149 TYR   F CE1 1 
ATOM   3390 C  CE2 . TYR   B 1 163 ? 12.070  -38.202 27.596  1.00 40.90  ? 149 TYR   F CE2 1 
ATOM   3391 C  CZ  . TYR   B 1 163 ? 12.072  -38.095 28.979  1.00 41.25  ? 149 TYR   F CZ  1 
ATOM   3392 O  OH  . TYR   B 1 163 ? 12.243  -39.189 29.786  1.00 43.12  ? 149 TYR   F OH  1 
ATOM   3393 N  N   . ALA   B 1 164 ? 13.834  -34.774 24.570  1.00 34.48  ? 150 ALA   F N   1 
ATOM   3394 C  CA  . ALA   B 1 164 ? 14.823  -35.614 23.860  1.00 37.32  ? 150 ALA   F CA  1 
ATOM   3395 C  C   . ALA   B 1 164 ? 16.181  -34.935 23.847  1.00 39.05  ? 150 ALA   F C   1 
ATOM   3396 O  O   . ALA   B 1 164 ? 17.183  -35.683 23.882  1.00 38.72  ? 150 ALA   F O   1 
ATOM   3397 C  CB  . ALA   B 1 164 ? 14.359  -35.932 22.466  1.00 37.01  ? 150 ALA   F CB  1 
ATOM   3398 N  N   . ARG   B 1 165 ? 16.218  -33.601 23.814  1.00 34.03  ? 151 ARG   F N   1 
ATOM   3399 C  CA  . ARG   B 1 165 ? 17.477  -32.812 23.778  1.00 38.67  ? 151 ARG   F CA  1 
ATOM   3400 C  C   . ARG   B 1 165 ? 17.974  -32.585 25.209  1.00 38.61  ? 151 ARG   F C   1 
ATOM   3401 O  O   . ARG   B 1 165 ? 18.937  -31.847 25.357  1.00 41.85  ? 151 ARG   F O   1 
ATOM   3402 C  CB  . ARG   B 1 165 ? 17.264  -31.456 23.085  1.00 40.29  ? 151 ARG   F CB  1 
ATOM   3403 C  CG  . ARG   B 1 165 ? 16.919  -31.565 21.600  1.00 42.35  ? 151 ARG   F CG  1 
ATOM   3404 C  CD  . ARG   B 1 165 ? 16.502  -30.234 20.984  1.00 45.88  ? 151 ARG   F CD  1 
ATOM   3405 N  NE  . ARG   B 1 165 ? 16.056  -30.347 19.584  1.00 47.83  ? 151 ARG   F NE  1 
ATOM   3406 C  CZ  . ARG   B 1 165 ? 16.870  -30.226 18.532  1.00 50.24  ? 151 ARG   F CZ  1 
ATOM   3407 N  NH1 . ARG   B 1 165 ? 18.157  -30.031 18.715  1.00 51.66  ? 151 ARG   F NH1 1 
ATOM   3408 N  NH2 . ARG   B 1 165 ? 16.412  -30.300 17.302  1.00 46.75  ? 151 ARG   F NH2 1 
ATOM   3409 N  N   . ASN   B 1 166 ? 17.262  -33.094 26.226  1.00 37.09  ? 152 ASN   F N   1 
ATOM   3410 C  CA  . ASN   B 1 166 ? 17.656  -32.927 27.655  1.00 42.18  ? 152 ASN   F CA  1 
ATOM   3411 C  C   . ASN   B 1 166 ? 17.729  -31.434 27.998  1.00 43.59  ? 152 ASN   F C   1 
ATOM   3412 O  O   . ASN   B 1 166 ? 18.668  -31.014 28.687  1.00 45.16  ? 152 ASN   F O   1 
ATOM   3413 C  CB  . ASN   B 1 166 ? 18.960  -33.697 27.961  1.00 42.99  ? 152 ASN   F CB  1 
ATOM   3414 C  CG  . ASN   B 1 166 ? 18.728  -35.195 27.976  1.00 46.16  ? 152 ASN   F CG  1 
ATOM   3415 O  OD1 . ASN   B 1 166 ? 18.044  -35.720 28.866  1.00 41.63  ? 152 ASN   F OD1 1 
ATOM   3416 N  ND2 . ASN   B 1 166 ? 19.221  -35.887 26.954  1.00 46.99  ? 152 ASN   F ND2 1 
ATOM   3417 N  N   . GLN   B 1 167 ? 16.770  -30.621 27.556  1.00 41.72  ? 153 GLN   F N   1 
ATOM   3418 C  CA  . GLN   B 1 167 ? 16.775  -29.178 27.948  1.00 46.11  ? 153 GLN   F CA  1 
ATOM   3419 C  C   . GLN   B 1 167 ? 16.230  -29.080 29.385  1.00 47.05  ? 153 GLN   F C   1 
ATOM   3420 O  O   . GLN   B 1 167 ? 15.138  -29.590 29.647  1.00 43.32  ? 153 GLN   F O   1 
ATOM   3421 C  CB  . GLN   B 1 167 ? 16.000  -28.321 26.948  1.00 51.56  ? 153 GLN   F CB  1 
ATOM   3422 C  CG  . GLN   B 1 167 ? 16.783  -28.160 25.645  1.00 75.56  ? 153 GLN   F CG  1 
ATOM   3423 C  CD  . GLN   B 1 167 ? 16.289  -27.055 24.740  1.00 87.25  ? 153 GLN   F CD  1 
ATOM   3424 O  OE1 . GLN   B 1 167 ? 16.793  -25.929 24.779  1.00 99.25  ? 153 GLN   F OE1 1 
ATOM   3425 N  NE2 . GLN   B 1 167 ? 15.308  -27.375 23.908  1.00 67.24  ? 153 GLN   F NE2 1 
ATOM   3426 N  N   . LYS   B 1 168 ? 16.972  -28.450 30.284  1.00 49.65  ? 154 LYS   F N   1 
ATOM   3427 C  CA  . LYS   B 1 168 ? 16.646  -28.353 31.740  1.00 55.26  ? 154 LYS   F CA  1 
ATOM   3428 C  C   . LYS   B 1 168 ? 16.097  -26.982 32.105  1.00 50.12  ? 154 LYS   F C   1 
ATOM   3429 O  O   . LYS   B 1 168 ? 15.421  -26.897 33.124  1.00 56.82  ? 154 LYS   F O   1 
ATOM   3430 C  CB  . LYS   B 1 168 ? 17.894  -28.644 32.579  1.00 62.13  ? 154 LYS   F CB  1 
ATOM   3431 C  CG  . LYS   B 1 168 ? 18.318  -30.111 32.598  1.00 67.85  ? 154 LYS   F CG  1 
ATOM   3432 C  CD  . LYS   B 1 168 ? 17.143  -31.083 32.693  1.00 67.26  ? 154 LYS   F CD  1 
ATOM   3433 C  CE  . LYS   B 1 168 ? 17.477  -32.420 33.310  1.00 70.49  ? 154 LYS   F CE  1 
ATOM   3434 N  NZ  . LYS   B 1 168 ? 17.718  -33.445 32.267  1.00 76.89  ? 154 LYS   F NZ  1 
ATOM   3435 N  N   . GLU   B 1 169 ? 16.364  -25.959 31.307  1.00 48.23  ? 155 GLU   F N   1 
ATOM   3436 C  CA  . GLU   B 1 169 ? 15.894  -24.578 31.571  1.00 57.91  ? 155 GLU   F CA  1 
ATOM   3437 C  C   . GLU   B 1 169 ? 14.698  -24.302 30.662  1.00 55.30  ? 155 GLU   F C   1 
ATOM   3438 O  O   . GLU   B 1 169 ? 14.379  -25.177 29.856  1.00 59.04  ? 155 GLU   F O   1 
ATOM   3439 C  CB  . GLU   B 1 169 ? 17.038  -23.603 31.318  1.00 62.10  ? 155 GLU   F CB  1 
ATOM   3440 C  CG  . GLU   B 1 169 ? 18.326  -24.097 31.946  1.00 73.10  ? 155 GLU   F CG  1 
ATOM   3441 C  CD  . GLU   B 1 169 ? 19.123  -23.018 32.642  1.00 77.57  ? 155 GLU   F CD  1 
ATOM   3442 O  OE1 . GLU   B 1 169 ? 20.179  -22.636 32.100  1.00 92.01  ? 155 GLU   F OE1 1 
ATOM   3443 O  OE2 . GLU   B 1 169 ? 18.664  -22.548 33.696  1.00 72.24  ? 155 GLU   F OE2 1 
ATOM   3444 N  N   . GLY   B 1 170 ? 14.082  -23.133 30.792  1.00 51.26  ? 156 GLY   F N   1 
ATOM   3445 C  CA  . GLY   B 1 170 ? 12.960  -22.718 29.935  1.00 49.82  ? 156 GLY   F CA  1 
ATOM   3446 C  C   . GLY   B 1 170 ? 11.627  -23.269 30.427  1.00 48.49  ? 156 GLY   F C   1 
ATOM   3447 O  O   . GLY   B 1 170 ? 11.530  -23.800 31.564  1.00 41.42  ? 156 GLY   F O   1 
ATOM   3448 N  N   . ALA   B 1 171 ? 10.591  -23.090 29.614  1.00 42.36  ? 157 ALA   F N   1 
ATOM   3449 C  CA  . ALA   B 1 171 ? 9.193   -23.110 30.061  1.00 43.33  ? 157 ALA   F CA  1 
ATOM   3450 C  C   . ALA   B 1 171 ? 8.616   -24.512 29.884  1.00 41.20  ? 157 ALA   F C   1 
ATOM   3451 O  O   . ALA   B 1 171 ? 7.432   -24.694 30.231  1.00 42.08  ? 157 ALA   F O   1 
ATOM   3452 C  CB  . ALA   B 1 171 ? 8.446   -22.036 29.302  1.00 47.58  ? 157 ALA   F CB  1 
ATOM   3453 N  N   . TYR   B 1 172 ? 9.422   -25.452 29.358  1.00 33.76  ? 158 TYR   F N   1 
ATOM   3454 C  CA  . TYR   B 1 172 ? 9.014   -26.852 29.120  1.00 33.96  ? 158 TYR   F CA  1 
ATOM   3455 C  C   . TYR   B 1 172 ? 9.767   -27.709 30.146  1.00 37.29  ? 158 TYR   F C   1 
ATOM   3456 O  O   . TYR   B 1 172 ? 10.977  -27.761 30.055  1.00 37.13  ? 158 TYR   F O   1 
ATOM   3457 C  CB  . TYR   B 1 172 ? 9.218   -27.263 27.646  1.00 35.49  ? 158 TYR   F CB  1 
ATOM   3458 C  CG  . TYR   B 1 172 ? 8.263   -26.520 26.736  1.00 33.42  ? 158 TYR   F CG  1 
ATOM   3459 C  CD1 . TYR   B 1 172 ? 6.953   -26.937 26.568  1.00 31.65  ? 158 TYR   F CD1 1 
ATOM   3460 C  CD2 . TYR   B 1 172 ? 8.653   -25.346 26.125  1.00 35.93  ? 158 TYR   F CD2 1 
ATOM   3461 C  CE1 . TYR   B 1 172 ? 6.047   -26.202 25.811  1.00 33.73  ? 158 TYR   F CE1 1 
ATOM   3462 C  CE2 . TYR   B 1 172 ? 7.773   -24.602 25.350  1.00 35.32  ? 158 TYR   F CE2 1 
ATOM   3463 C  CZ  . TYR   B 1 172 ? 6.469   -25.041 25.175  1.00 34.19  ? 158 TYR   F CZ  1 
ATOM   3464 O  OH  . TYR   B 1 172 ? 5.578   -24.312 24.439  1.00 34.02  ? 158 TYR   F OH  1 
ATOM   3465 N  N   . ILE   B 1 173 ? 9.076   -28.276 31.131  1.00 35.44  ? 159 ILE   F N   1 
ATOM   3466 C  CA  . ILE   B 1 173 ? 9.744   -28.848 32.349  1.00 32.30  ? 159 ILE   F CA  1 
ATOM   3467 C  C   . ILE   B 1 173 ? 10.068  -30.316 32.106  1.00 34.18  ? 159 ILE   F C   1 
ATOM   3468 O  O   . ILE   B 1 173 ? 9.120   -31.149 31.975  1.00 32.75  ? 159 ILE   F O   1 
ATOM   3469 C  CB  . ILE   B 1 173 ? 8.839   -28.692 33.579  1.00 34.14  ? 159 ILE   F CB  1 
ATOM   3470 C  CG1 . ILE   B 1 173 ? 8.441   -27.235 33.850  1.00 36.89  ? 159 ILE   F CG1 1 
ATOM   3471 C  CG2 . ILE   B 1 173 ? 9.534   -29.343 34.777  1.00 37.89  ? 159 ILE   F CG2 1 
ATOM   3472 C  CD1 . ILE   B 1 173 ? 9.625   -26.263 33.917  1.00 40.54  ? 159 ILE   F CD1 1 
ATOM   3473 N  N   . TRP   B 1 174 ? 11.349  -30.633 32.004  1.00 34.12  ? 160 TRP   F N   1 
ATOM   3474 C  CA  . TRP   B 1 174 ? 11.849  -31.996 31.681  1.00 37.27  ? 160 TRP   F CA  1 
ATOM   3475 C  C   . TRP   B 1 174 ? 11.178  -33.042 32.567  1.00 36.28  ? 160 TRP   F C   1 
ATOM   3476 O  O   . TRP   B 1 174 ? 10.735  -34.082 32.050  1.00 35.31  ? 160 TRP   F O   1 
ATOM   3477 C  CB  . TRP   B 1 174 ? 13.371  -32.047 31.839  1.00 38.26  ? 160 TRP   F CB  1 
ATOM   3478 C  CG  . TRP   B 1 174 ? 13.947  -33.230 31.130  1.00 38.43  ? 160 TRP   F CG  1 
ATOM   3479 C  CD1 . TRP   B 1 174 ? 14.326  -33.266 29.822  1.00 42.42  ? 160 TRP   F CD1 1 
ATOM   3480 C  CD2 . TRP   B 1 174 ? 14.171  -34.550 31.662  1.00 41.37  ? 160 TRP   F CD2 1 
ATOM   3481 N  NE1 . TRP   B 1 174 ? 14.789  -34.517 29.511  1.00 40.51  ? 160 TRP   F NE1 1 
ATOM   3482 C  CE2 . TRP   B 1 174 ? 14.719  -35.323 30.613  1.00 43.51  ? 160 TRP   F CE2 1 
ATOM   3483 C  CE3 . TRP   B 1 174 ? 13.969  -35.159 32.914  1.00 41.18  ? 160 TRP   F CE3 1 
ATOM   3484 C  CZ2 . TRP   B 1 174 ? 15.049  -36.673 30.767  1.00 42.38  ? 160 TRP   F CZ2 1 
ATOM   3485 C  CZ3 . TRP   B 1 174 ? 14.300  -36.490 33.067  1.00 43.24  ? 160 TRP   F CZ3 1 
ATOM   3486 C  CH2 . TRP   B 1 174 ? 14.843  -37.231 32.010  1.00 44.54  ? 160 TRP   F CH2 1 
ATOM   3487 N  N   . ALA   B 1 175 ? 11.150  -32.802 33.891  1.00 38.01  ? 161 ALA   F N   1 
ATOM   3488 C  CA  . ALA   B 1 175 ? 10.649  -33.792 34.866  1.00 37.70  ? 161 ALA   F CA  1 
ATOM   3489 C  C   . ALA   B 1 175 ? 9.135   -33.940 34.712  1.00 36.83  ? 161 ALA   F C   1 
ATOM   3490 O  O   . ALA   B 1 175 ? 8.627   -35.061 34.928  1.00 37.38  ? 161 ALA   F O   1 
ATOM   3491 C  CB  . ALA   B 1 175 ? 11.077  -33.380 36.264  1.00 43.30  ? 161 ALA   F CB  1 
ATOM   3492 N  N   . ASP   B 1 176 ? 8.419   -32.885 34.276  1.00 36.01  ? 162 ASP   F N   1 
ATOM   3493 C  CA  . ASP   B 1 176 ? 6.961   -33.017 34.020  1.00 34.69  ? 162 ASP   F CA  1 
ATOM   3494 C  C   . ASP   B 1 176 ? 6.776   -33.994 32.841  1.00 35.49  ? 162 ASP   F C   1 
ATOM   3495 O  O   . ASP   B 1 176 ? 5.948   -34.942 32.906  1.00 34.00  ? 162 ASP   F O   1 
ATOM   3496 C  CB  . ASP   B 1 176 ? 6.277   -31.650 33.817  1.00 34.97  ? 162 ASP   F CB  1 
ATOM   3497 C  CG  . ASP   B 1 176 ? 6.065   -30.790 35.066  1.00 39.19  ? 162 ASP   F CG  1 
ATOM   3498 O  OD1 . ASP   B 1 176 ? 6.414   -31.251 36.179  1.00 41.91  ? 162 ASP   F OD1 1 
ATOM   3499 O  OD2 . ASP   B 1 176 ? 5.539   -29.633 34.931  1.00 38.75  ? 162 ASP   F OD2 1 
ATOM   3500 N  N   . ILE   B 1 177 ? 7.516   -33.768 31.759  1.00 35.94  ? 163 ILE   F N   1 
ATOM   3501 C  CA  . ILE   B 1 177 ? 7.371   -34.583 30.523  1.00 33.69  ? 163 ILE   F CA  1 
ATOM   3502 C  C   . ILE   B 1 177 ? 7.776   -36.026 30.848  1.00 32.71  ? 163 ILE   F C   1 
ATOM   3503 O  O   . ILE   B 1 177 ? 7.065   -36.981 30.423  1.00 32.67  ? 163 ILE   F O   1 
ATOM   3504 C  CB  . ILE   B 1 177 ? 8.203   -33.957 29.382  1.00 35.03  ? 163 ILE   F CB  1 
ATOM   3505 C  CG1 . ILE   B 1 177 ? 7.805   -32.498 29.120  1.00 35.75  ? 163 ILE   F CG1 1 
ATOM   3506 C  CG2 . ILE   B 1 177 ? 8.059   -34.789 28.116  1.00 34.63  ? 163 ILE   F CG2 1 
ATOM   3507 C  CD1 . ILE   B 1 177 ? 8.836   -31.724 28.352  1.00 37.15  ? 163 ILE   F CD1 1 
ATOM   3508 N  N   . ASP   B 1 178 ? 8.869   -36.175 31.604  1.00 37.43  ? 164 ASP   F N   1 
ATOM   3509 C  CA  . ASP   B 1 178 ? 9.324   -37.506 32.088  1.00 38.31  ? 164 ASP   F CA  1 
ATOM   3510 C  C   . ASP   B 1 178 ? 8.128   -38.232 32.721  1.00 36.85  ? 164 ASP   F C   1 
ATOM   3511 O  O   . ASP   B 1 178 ? 7.842   -39.416 32.331  1.00 34.81  ? 164 ASP   F O   1 
ATOM   3512 C  CB  . ASP   B 1 178 ? 10.538  -37.376 33.009  1.00 41.89  ? 164 ASP   F CB  1 
ATOM   3513 C  CG  . ASP   B 1 178 ? 11.252  -38.704 33.236  1.00 50.61  ? 164 ASP   F CG  1 
ATOM   3514 O  OD1 . ASP   B 1 178 ? 11.552  -39.391 32.253  1.00 43.93  ? 164 ASP   F OD1 1 
ATOM   3515 O  OD2 . ASP   B 1 178 ? 11.416  -39.074 34.383  1.00 49.44  ? 164 ASP   F OD2 1 
ATOM   3516 N  N   . ALA   B 1 179 ? 7.379   -37.553 33.598  1.00 40.64  ? 165 ALA   F N   1 
ATOM   3517 C  CA  . ALA   B 1 179 ? 6.227   -38.178 34.300  1.00 37.77  ? 165 ALA   F CA  1 
ATOM   3518 C  C   . ALA   B 1 179 ? 5.086   -38.481 33.317  1.00 36.32  ? 165 ALA   F C   1 
ATOM   3519 O  O   . ALA   B 1 179 ? 4.434   -39.561 33.438  1.00 36.86  ? 165 ALA   F O   1 
ATOM   3520 C  CB  . ALA   B 1 179 ? 5.802   -37.324 35.467  1.00 38.10  ? 165 ALA   F CB  1 
ATOM   3521 N  N   . TRP   B 1 180 ? 4.828   -37.626 32.318  1.00 38.12  ? 166 TRP   F N   1 
ATOM   3522 C  CA  . TRP   B 1 180 ? 3.745   -37.928 31.331  1.00 37.73  ? 166 TRP   F CA  1 
ATOM   3523 C  C   . TRP   B 1 180 ? 4.019   -39.259 30.649  1.00 37.67  ? 166 TRP   F C   1 
ATOM   3524 O  O   . TRP   B 1 180 ? 3.071   -40.006 30.452  1.00 39.96  ? 166 TRP   F O   1 
ATOM   3525 C  CB  . TRP   B 1 180 ? 3.548   -36.843 30.266  1.00 37.05  ? 166 TRP   F CB  1 
ATOM   3526 C  CG  . TRP   B 1 180 ? 3.473   -35.456 30.808  1.00 35.14  ? 166 TRP   F CG  1 
ATOM   3527 C  CD1 . TRP   B 1 180 ? 3.091   -35.089 32.075  1.00 36.67  ? 166 TRP   F CD1 1 
ATOM   3528 C  CD2 . TRP   B 1 180 ? 3.709   -34.239 30.081  1.00 37.75  ? 166 TRP   F CD2 1 
ATOM   3529 N  NE1 . TRP   B 1 180 ? 3.173   -33.729 32.205  1.00 36.47  ? 166 TRP   F NE1 1 
ATOM   3530 C  CE2 . TRP   B 1 180 ? 3.516   -33.176 30.991  1.00 38.81  ? 166 TRP   F CE2 1 
ATOM   3531 C  CE3 . TRP   B 1 180 ? 4.078   -33.949 28.750  1.00 38.21  ? 166 TRP   F CE3 1 
ATOM   3532 C  CZ2 . TRP   B 1 180 ? 3.718   -31.837 30.634  1.00 38.84  ? 166 TRP   F CZ2 1 
ATOM   3533 C  CZ3 . TRP   B 1 180 ? 4.255   -32.625 28.399  1.00 37.27  ? 166 TRP   F CZ3 1 
ATOM   3534 C  CH2 . TRP   B 1 180 ? 4.114   -31.597 29.331  1.00 38.71  ? 166 TRP   F CH2 1 
ATOM   3535 N  N   . ILE   B 1 181 ? 5.265   -39.513 30.255  1.00 38.29  ? 167 ILE   F N   1 
ATOM   3536 C  CA  . ILE   B 1 181 ? 5.648   -40.760 29.529  1.00 41.28  ? 167 ILE   F CA  1 
ATOM   3537 C  C   . ILE   B 1 181 ? 5.635   -41.954 30.504  1.00 39.36  ? 167 ILE   F C   1 
ATOM   3538 O  O   . ILE   B 1 181 ? 5.034   -42.985 30.188  1.00 42.05  ? 167 ILE   F O   1 
ATOM   3539 C  CB  . ILE   B 1 181 ? 7.040   -40.569 28.885  1.00 41.17  ? 167 ILE   F CB  1 
ATOM   3540 C  CG1 . ILE   B 1 181 ? 7.031   -39.387 27.921  1.00 40.93  ? 167 ILE   F CG1 1 
ATOM   3541 C  CG2 . ILE   B 1 181 ? 7.562   -41.868 28.246  1.00 39.88  ? 167 ILE   F CG2 1 
ATOM   3542 C  CD1 . ILE   B 1 181 ? 8.403   -38.991 27.473  1.00 45.33  ? 167 ILE   F CD1 1 
ATOM   3543 N  N   . LYS   B 1 182 ? 6.226   -41.812 31.685  1.00 43.06  ? 168 LYS   F N   1 
ATOM   3544 C  CA  . LYS   B 1 182 ? 6.207   -42.924 32.676  1.00 43.68  ? 168 LYS   F CA  1 
ATOM   3545 C  C   . LYS   B 1 182 ? 4.780   -43.293 33.084  1.00 45.72  ? 168 LYS   F C   1 
ATOM   3546 O  O   . LYS   B 1 182 ? 4.531   -44.496 33.269  1.00 43.05  ? 168 LYS   F O   1 
ATOM   3547 C  CB  . LYS   B 1 182 ? 7.087   -42.555 33.864  1.00 54.73  ? 168 LYS   F CB  1 
ATOM   3548 C  CG  . LYS   B 1 182 ? 8.566   -42.734 33.561  1.00 54.53  ? 168 LYS   F CG  1 
ATOM   3549 C  CD  . LYS   B 1 182 ? 9.449   -42.095 34.567  1.00 63.83  ? 168 LYS   F CD  1 
ATOM   3550 C  CE  . LYS   B 1 182 ? 10.918  -42.262 34.230  1.00 68.22  ? 168 LYS   F CE  1 
ATOM   3551 N  NZ  . LYS   B 1 182 ? 11.737  -41.584 35.264  1.00 72.38  ? 168 LYS   F NZ  1 
ATOM   3552 N  N   . ASN   B 1 183 ? 3.852   -42.323 33.165  1.00 43.40  ? 169 ASN   F N   1 
ATOM   3553 C  CA  . ASN   B 1 183 ? 2.456   -42.578 33.605  1.00 42.69  ? 169 ASN   F CA  1 
ATOM   3554 C  C   . ASN   B 1 183 ? 1.600   -43.059 32.437  1.00 41.93  ? 169 ASN   F C   1 
ATOM   3555 O  O   . ASN   B 1 183 ? 0.422   -43.342 32.660  1.00 40.31  ? 169 ASN   F O   1 
ATOM   3556 C  CB  . ASN   B 1 183 ? 1.836   -41.372 34.322  1.00 46.54  ? 169 ASN   F CB  1 
ATOM   3557 C  CG  . ASN   B 1 183 ? 2.431   -41.107 35.697  1.00 50.62  ? 169 ASN   F CG  1 
ATOM   3558 O  OD1 . ASN   B 1 183 ? 3.538   -41.489 35.999  1.00 53.38  ? 169 ASN   F OD1 1 
ATOM   3559 N  ND2 . ASN   B 1 183 ? 1.760   -40.333 36.516  1.00 61.86  ? 169 ASN   F ND2 1 
ATOM   3560 N  N   . ASN   B 1 184 ? 2.148   -43.182 31.227  1.00 44.21  ? 170 ASN   F N   1 
ATOM   3561 C  CA  . ASN   B 1 184 ? 1.418   -43.765 30.078  1.00 39.36  ? 170 ASN   F CA  1 
ATOM   3562 C  C   . ASN   B 1 184 ? 0.112   -42.983 29.803  1.00 36.38  ? 170 ASN   F C   1 
ATOM   3563 O  O   . ASN   B 1 184 ? -0.957  -43.590 29.576  1.00 39.15  ? 170 ASN   F O   1 
ATOM   3564 C  CB  . ASN   B 1 184 ? 1.156   -45.246 30.345  1.00 44.59  ? 170 ASN   F CB  1 
ATOM   3565 C  CG  . ASN   B 1 184 ? 0.894   -45.967 29.054  1.00 50.51  ? 170 ASN   F CG  1 
ATOM   3566 O  OD1 . ASN   B 1 184 ? 1.418   -45.584 28.016  1.00 55.09  ? 170 ASN   F OD1 1 
ATOM   3567 N  ND2 . ASN   B 1 184 ? 0.034   -46.959 29.101  1.00 57.64  ? 170 ASN   F ND2 1 
ATOM   3568 N  N   . LEU   B 1 185 ? 0.197   -41.660 29.735  1.00 37.03  ? 171 LEU   F N   1 
ATOM   3569 C  CA  . LEU   B 1 185 ? -0.963  -40.826 29.332  1.00 36.02  ? 171 LEU   F CA  1 
ATOM   3570 C  C   . LEU   B 1 185 ? -1.408  -41.228 27.935  1.00 42.86  ? 171 LEU   F C   1 
ATOM   3571 O  O   . LEU   B 1 185 ? -0.547  -41.692 27.134  1.00 38.51  ? 171 LEU   F O   1 
ATOM   3572 C  CB  . LEU   B 1 185 ? -0.622  -39.338 29.428  1.00 35.88  ? 171 LEU   F CB  1 
ATOM   3573 C  CG  . LEU   B 1 185 ? -0.233  -38.903 30.846  1.00 36.93  ? 171 LEU   F CG  1 
ATOM   3574 C  CD1 . LEU   B 1 185 ? 0.007   -37.399 30.937  1.00 33.38  ? 171 LEU   F CD1 1 
ATOM   3575 C  CD2 . LEU   B 1 185 ? -1.308  -39.347 31.828  1.00 37.93  ? 171 LEU   F CD2 1 
ATOM   3576 N  N   . GLN   B 1 186 ? -2.715  -41.080 27.696  1.00 38.09  ? 172 GLN   F N   1 
ATOM   3577 C  CA  . GLN   B 1 186 ? -3.383  -41.356 26.398  1.00 39.72  ? 172 GLN   F CA  1 
ATOM   3578 C  C   . GLN   B 1 186 ? -3.612  -40.021 25.662  1.00 42.91  ? 172 GLN   F C   1 
ATOM   3579 O  O   . GLN   B 1 186 ? -4.441  -39.214 26.113  1.00 40.05  ? 172 GLN   F O   1 
ATOM   3580 C  CB  . GLN   B 1 186 ? -4.699  -42.098 26.629  1.00 40.97  ? 172 GLN   F CB  1 
ATOM   3581 C  CG  . GLN   B 1 186 ? -4.502  -43.448 27.320  1.00 45.34  ? 172 GLN   F CG  1 
ATOM   3582 C  CD  . GLN   B 1 186 ? -3.547  -44.330 26.551  1.00 40.50  ? 172 GLN   F CD  1 
ATOM   3583 O  OE1 . GLN   B 1 186 ? -3.824  -44.755 25.442  1.00 48.40  ? 172 GLN   F OE1 1 
ATOM   3584 N  NE2 . GLN   B 1 186 ? -2.410  -44.611 27.139  1.00 44.74  ? 172 GLN   F NE2 1 
ATOM   3585 N  N   . TRP   B 1 187 ? -2.904  -39.811 24.558  1.00 37.94  ? 173 TRP   F N   1 
ATOM   3586 C  CA  . TRP   B 1 187 ? -2.913  -38.525 23.817  1.00 38.78  ? 173 TRP   F CA  1 
ATOM   3587 C  C   . TRP   B 1 187 ? -3.810  -38.601 22.590  1.00 38.98  ? 173 TRP   F C   1 
ATOM   3588 O  O   . TRP   B 1 187 ? -3.770  -39.595 21.887  1.00 37.27  ? 173 TRP   F O   1 
ATOM   3589 C  CB  . TRP   B 1 187 ? -1.482  -38.138 23.432  1.00 35.42  ? 173 TRP   F CB  1 
ATOM   3590 C  CG  . TRP   B 1 187 ? -0.528  -38.050 24.582  1.00 35.45  ? 173 TRP   F CG  1 
ATOM   3591 C  CD1 . TRP   B 1 187 ? 0.244   -39.039 25.107  1.00 39.62  ? 173 TRP   F CD1 1 
ATOM   3592 C  CD2 . TRP   B 1 187 ? -0.214  -36.864 25.317  1.00 35.69  ? 173 TRP   F CD2 1 
ATOM   3593 N  NE1 . TRP   B 1 187 ? 1.045   -38.533 26.091  1.00 37.15  ? 173 TRP   F NE1 1 
ATOM   3594 C  CE2 . TRP   B 1 187 ? 0.777   -37.211 26.262  1.00 37.41  ? 173 TRP   F CE2 1 
ATOM   3595 C  CE3 . TRP   B 1 187 ? -0.636  -35.533 25.217  1.00 35.98  ? 173 TRP   F CE3 1 
ATOM   3596 C  CZ2 . TRP   B 1 187 ? 1.337   -36.287 27.135  1.00 38.66  ? 173 TRP   F CZ2 1 
ATOM   3597 C  CZ3 . TRP   B 1 187 ? -0.114  -34.622 26.112  1.00 38.53  ? 173 TRP   F CZ3 1 
ATOM   3598 C  CH2 . TRP   B 1 187 ? 0.875   -34.994 27.037  1.00 38.86  ? 173 TRP   F CH2 1 
ATOM   3599 N  N   . ARG   B 1 188 ? -4.554  -37.526 22.343  1.00 36.78  ? 174 ARG   F N   1 
ATOM   3600 C  CA  . ARG   B 1 188 ? -5.199  -37.237 21.041  1.00 38.38  ? 174 ARG   F CA  1 
ATOM   3601 C  C   . ARG   B 1 188 ? -4.618  -35.894 20.600  1.00 35.38  ? 174 ARG   F C   1 
ATOM   3602 O  O   . ARG   B 1 188 ? -4.922  -34.859 21.246  1.00 35.61  ? 174 ARG   F O   1 
ATOM   3603 C  CB  . ARG   B 1 188 ? -6.734  -37.199 21.100  1.00 43.98  ? 174 ARG   F CB  1 
ATOM   3604 C  CG  . ARG   B 1 188 ? -7.388  -37.050 19.723  1.00 50.80  ? 174 ARG   F CG  1 
ATOM   3605 C  CD  . ARG   B 1 188 ? -8.344  -35.884 19.611  1.00 60.43  ? 174 ARG   F CD  1 
ATOM   3606 N  NE  . ARG   B 1 188 ? -9.201  -35.846 18.429  1.00 53.71  ? 174 ARG   F NE  1 
ATOM   3607 C  CZ  . ARG   B 1 188 ? -8.909  -35.297 17.248  1.00 58.33  ? 174 ARG   F CZ  1 
ATOM   3608 N  NH1 . ARG   B 1 188 ? -7.723  -34.762 16.990  1.00 50.44  ? 174 ARG   F NH1 1 
ATOM   3609 N  NH2 . ARG   B 1 188 ? -9.829  -35.300 16.300  1.00 53.30  ? 174 ARG   F NH2 1 
ATOM   3610 N  N   . THR   B 1 189 ? -3.801  -35.899 19.547  1.00 31.41  ? 175 THR   F N   1 
ATOM   3611 C  CA  . THR   B 1 189 ? -3.218  -34.638 19.027  1.00 31.60  ? 175 THR   F CA  1 
ATOM   3612 C  C   . THR   B 1 189 ? -4.216  -33.989 18.071  1.00 33.24  ? 175 THR   F C   1 
ATOM   3613 O  O   . THR   B 1 189 ? -4.880  -34.702 17.276  1.00 33.68  ? 175 THR   F O   1 
ATOM   3614 C  CB  . THR   B 1 189 ? -1.850  -34.867 18.400  1.00 34.23  ? 175 THR   F CB  1 
ATOM   3615 O  OG1 . THR   B 1 189 ? -2.006  -35.898 17.435  1.00 34.74  ? 175 THR   F OG1 1 
ATOM   3616 C  CG2 . THR   B 1 189 ? -0.810  -35.239 19.430  1.00 36.66  ? 175 THR   F CG2 1 
ATOM   3617 N  N   . VAL   B 1 190 ? -4.384  -32.681 18.204  1.00 30.82  ? 176 VAL   F N   1 
ATOM   3618 C  CA  . VAL   B 1 190 ? -5.129  -31.853 17.210  1.00 30.29  ? 176 VAL   F CA  1 
ATOM   3619 C  C   . VAL   B 1 190 ? -4.155  -31.498 16.074  1.00 31.06  ? 176 VAL   F C   1 
ATOM   3620 O  O   . VAL   B 1 190 ? -3.103  -30.873 16.329  1.00 31.78  ? 176 VAL   F O   1 
ATOM   3621 C  CB  . VAL   B 1 190 ? -5.727  -30.619 17.911  1.00 33.02  ? 176 VAL   F CB  1 
ATOM   3622 C  CG1 . VAL   B 1 190 ? -6.497  -29.747 16.915  1.00 34.31  ? 176 VAL   F CG1 1 
ATOM   3623 C  CG2 . VAL   B 1 190 ? -6.609  -31.050 19.084  1.00 31.83  ? 176 VAL   F CG2 1 
ATOM   3624 N  N   . LYS   B 1 191 ? -4.482  -31.902 14.854  1.00 34.53  ? 177 LYS   F N   1 
ATOM   3625 C  CA  . LYS   B 1 191 ? -3.592  -31.711 13.680  1.00 33.68  ? 177 LYS   F CA  1 
ATOM   3626 C  C   . LYS   B 1 191 ? -3.603  -30.240 13.291  1.00 35.29  ? 177 LYS   F C   1 
ATOM   3627 O  O   . LYS   B 1 191 ? -4.593  -29.492 13.579  1.00 33.52  ? 177 LYS   F O   1 
ATOM   3628 C  CB  . LYS   B 1 191 ? -4.000  -32.589 12.494  1.00 35.15  ? 177 LYS   F CB  1 
ATOM   3629 C  CG  . LYS   B 1 191 ? -4.163  -34.081 12.797  1.00 46.67  ? 177 LYS   F CG  1 
ATOM   3630 C  CD  . LYS   B 1 191 ? -2.959  -34.752 13.437  1.00 53.65  ? 177 LYS   F CD  1 
ATOM   3631 C  CE  . LYS   B 1 191 ? -3.151  -36.244 13.721  1.00 54.05  ? 177 LYS   F CE  1 
ATOM   3632 N  NZ  . LYS   B 1 191 ? -3.825  -36.524 15.024  1.00 49.91  ? 177 LYS   F NZ  1 
ATOM   3633 N  N   . ARG   B 1 192 ? -2.512  -29.827 12.681  1.00 35.52  ? 178 ARG   F N   1 
ATOM   3634 C  CA  . ARG   B 1 192 ? -2.292  -28.426 12.309  1.00 40.01  ? 178 ARG   F CA  1 
ATOM   3635 C  C   . ARG   B 1 192 ? -3.523  -27.868 11.576  1.00 42.90  ? 178 ARG   F C   1 
ATOM   3636 O  O   . ARG   B 1 192 ? -3.907  -26.769 11.878  1.00 45.91  ? 178 ARG   F O   1 
ATOM   3637 C  CB  . ARG   B 1 192 ? -0.985  -28.324 11.525  1.00 37.50  ? 178 ARG   F CB  1 
ATOM   3638 C  CG  . ARG   B 1 192 ? -0.560  -26.880 11.295  1.00 40.65  ? 178 ARG   F CG  1 
ATOM   3639 C  CD  . ARG   B 1 192 ? 0.708   -26.801 10.463  1.00 39.44  ? 178 ARG   F CD  1 
ATOM   3640 N  NE  . ARG   B 1 192 ? 1.846   -27.205 11.258  1.00 33.15  ? 178 ARG   F NE  1 
ATOM   3641 C  CZ  . ARG   B 1 192 ? 3.053   -27.299 10.790  1.00 36.45  ? 178 ARG   F CZ  1 
ATOM   3642 N  NH1 . ARG   B 1 192 ? 3.279   -27.052 9.506   1.00 33.07  ? 178 ARG   F NH1 1 
ATOM   3643 N  NH2 . ARG   B 1 192 ? 4.025   -27.688 11.593  1.00 35.15  ? 178 ARG   F NH2 1 
ATOM   3644 N  N   . HIS   B 1 193 ? -4.153  -28.578 10.645  1.00 45.21  ? 179 HIS   F N   1 
ATOM   3645 C  CA  . HIS   B 1 193 ? -5.231  -27.948 9.821   1.00 53.95  ? 179 HIS   F CA  1 
ATOM   3646 C  C   . HIS   B 1 193 ? -6.585  -28.487 10.314  1.00 57.09  ? 179 HIS   F C   1 
ATOM   3647 O  O   . HIS   B 1 193 ? -7.571  -28.439 9.574   1.00 55.28  ? 179 HIS   F O   1 
ATOM   3648 C  CB  . HIS   B 1 193 ? -4.903  -28.106 8.305   1.00 57.39  ? 179 HIS   F CB  1 
ATOM   3649 C  CG  . HIS   B 1 193 ? -3.615  -27.436 7.918   1.00 63.91  ? 179 HIS   F CG  1 
ATOM   3650 N  ND1 . HIS   B 1 193 ? -3.378  -26.077 8.192   1.00 61.50  ? 179 HIS   F ND1 1 
ATOM   3651 C  CD2 . HIS   B 1 193 ? -2.469  -27.919 7.369   1.00 66.05  ? 179 HIS   F CD2 1 
ATOM   3652 C  CE1 . HIS   B 1 193 ? -2.147  -25.755 7.808   1.00 61.24  ? 179 HIS   F CE1 1 
ATOM   3653 N  NE2 . HIS   B 1 193 ? -1.569  -26.867 7.289   1.00 65.67  ? 179 HIS   F NE2 1 
ATOM   3654 N  N   . GLU   B 1 194 ? -6.644  -28.980 11.550  1.00 43.18  ? 180 GLU   F N   1 
ATOM   3655 C  CA  . GLU   B 1 194 ? -7.832  -29.704 12.025  1.00 43.29  ? 180 GLU   F CA  1 
ATOM   3656 C  C   . GLU   B 1 194 ? -8.802  -28.686 12.577  1.00 48.78  ? 180 GLU   F C   1 
ATOM   3657 O  O   . GLU   B 1 194 ? -8.401  -27.833 13.386  1.00 43.78  ? 180 GLU   F O   1 
ATOM   3658 C  CB  . GLU   B 1 194 ? -7.537  -30.746 13.087  1.00 46.81  ? 180 GLU   F CB  1 
ATOM   3659 C  CG  . GLU   B 1 194 ? -8.661  -31.729 13.277  1.00 44.43  ? 180 GLU   F CG  1 
ATOM   3660 C  CD  . GLU   B 1 194 ? -8.357  -32.892 14.223  1.00 50.15  ? 180 GLU   F CD  1 
ATOM   3661 O  OE1 . GLU   B 1 194 ? -7.163  -33.143 14.581  1.00 41.67  ? 180 GLU   F OE1 1 
ATOM   3662 O  OE2 . GLU   B 1 194 ? -9.332  -33.510 14.651  1.00 50.58  ? 180 GLU   F OE2 1 
ATOM   3663 N  N   . ASP   B 1 195 ? -9.997  -28.813 12.040  1.00 56.60  ? 181 ASP   F N   1 
ATOM   3664 C  CA  . ASP   B 1 195 ? -11.256 -28.163 12.432  1.00 74.31  ? 181 ASP   F CA  1 
ATOM   3665 C  C   . ASP   B 1 195 ? -11.326 -28.137 13.953  1.00 60.05  ? 181 ASP   F C   1 
ATOM   3666 O  O   . ASP   B 1 195 ? -10.435 -28.643 14.599  1.00 79.76  ? 181 ASP   F O   1 
ATOM   3667 C  CB  . ASP   B 1 195 ? -12.427 -28.931 11.792  1.00 75.03  ? 181 ASP   F CB  1 
ATOM   3668 C  CG  . ASP   B 1 195 ? -12.820 -28.485 10.387  1.00 84.12  ? 181 ASP   F CG  1 
ATOM   3669 O  OD1 . ASP   B 1 195 ? -12.026 -27.752 9.736   1.00 75.78  ? 181 ASP   F OD1 1 
ATOM   3670 O  OD2 . ASP   B 1 195 ? -13.920 -28.889 9.953   1.00 75.62  ? 181 ASP   F OD2 1 
ATOM   3671 N  N   . ASN   B 1 196 ? -12.423 -27.617 14.448  1.00 42.96  ? 182 ASN   F N   1 
ATOM   3672 C  CA  . ASN   B 1 196 ? -12.731 -27.345 15.866  1.00 44.13  ? 182 ASN   F CA  1 
ATOM   3673 C  C   . ASN   B 1 196 ? -13.682 -28.449 16.406  1.00 48.07  ? 182 ASN   F C   1 
ATOM   3674 O  O   . ASN   B 1 196 ? -14.821 -28.596 15.982  1.00 48.06  ? 182 ASN   F O   1 
ATOM   3675 C  CB  . ASN   B 1 196 ? -13.392 -26.000 16.044  1.00 58.38  ? 182 ASN   F CB  1 
ATOM   3676 C  CG  . ASN   B 1 196 ? -12.612 -24.817 15.500  1.00 71.90  ? 182 ASN   F CG  1 
ATOM   3677 O  OD1 . ASN   B 1 196 ? -13.302 -23.899 15.044  1.00 81.31  ? 182 ASN   F OD1 1 
ATOM   3678 N  ND2 . ASN   B 1 196 ? -11.258 -24.806 15.522  1.00 48.00  ? 182 ASN   F ND2 1 
ATOM   3679 N  N   . ILE   B 1 197 ? -13.231 -29.159 17.408  1.00 36.67  ? 183 ILE   F N   1 
ATOM   3680 C  CA  . ILE   B 1 197 ? -13.656 -30.532 17.760  1.00 37.52  ? 183 ILE   F CA  1 
ATOM   3681 C  C   . ILE   B 1 197 ? -14.773 -30.459 18.791  1.00 36.18  ? 183 ILE   F C   1 
ATOM   3682 O  O   . ILE   B 1 197 ? -14.587 -29.792 19.846  1.00 36.49  ? 183 ILE   F O   1 
ATOM   3683 C  CB  . ILE   B 1 197 ? -12.432 -31.290 18.296  1.00 43.19  ? 183 ILE   F CB  1 
ATOM   3684 C  CG1 . ILE   B 1 197 ? -11.299 -31.302 17.266  1.00 46.30  ? 183 ILE   F CG1 1 
ATOM   3685 C  CG2 . ILE   B 1 197 ? -12.800 -32.684 18.782  1.00 45.65  ? 183 ILE   F CG2 1 
ATOM   3686 C  CD1 . ILE   B 1 197 ? -9.963  -31.556 17.897  1.00 50.40  ? 183 ILE   F CD1 1 
ATOM   3687 N  N   . LEU   B 1 198 ? -15.907 -31.077 18.464  1.00 35.97  ? 184 LEU   F N   1 
ATOM   3688 C  CA  . LEU   B 1 198 ? -17.089 -31.173 19.351  1.00 45.87  ? 184 LEU   F CA  1 
ATOM   3689 C  C   . LEU   B 1 198 ? -16.769 -32.237 20.399  1.00 43.12  ? 184 LEU   F C   1 
ATOM   3690 O  O   . LEU   B 1 198 ? -16.588 -33.393 20.040  1.00 45.30  ? 184 LEU   F O   1 
ATOM   3691 C  CB  . LEU   B 1 198 ? -18.350 -31.524 18.556  1.00 53.92  ? 184 LEU   F CB  1 
ATOM   3692 C  CG  . LEU   B 1 198 ? -19.636 -31.422 19.392  1.00 66.69  ? 184 LEU   F CG  1 
ATOM   3693 C  CD1 . LEU   B 1 198 ? -19.869 -29.973 19.834  1.00 67.80  ? 184 LEU   F CD1 1 
ATOM   3694 C  CD2 . LEU   B 1 198 ? -20.851 -31.955 18.631  1.00 70.76  ? 184 LEU   F CD2 1 
ATOM   3695 N  N   . LEU   B 1 199 ? -16.569 -31.831 21.645  1.00 42.94  ? 185 LEU   F N   1 
ATOM   3696 C  CA  . LEU   B 1 199 ? -16.216 -32.759 22.738  1.00 40.31  ? 185 LEU   F CA  1 
ATOM   3697 C  C   . LEU   B 1 199 ? -17.479 -33.311 23.388  1.00 40.35  ? 185 LEU   F C   1 
ATOM   3698 O  O   . LEU   B 1 199 ? -17.464 -34.452 23.835  1.00 44.93  ? 185 LEU   F O   1 
ATOM   3699 C  CB  . LEU   B 1 199 ? -15.391 -32.001 23.768  1.00 43.46  ? 185 LEU   F CB  1 
ATOM   3700 C  CG  . LEU   B 1 199 ? -13.882 -32.122 23.658  1.00 48.42  ? 185 LEU   F CG  1 
ATOM   3701 C  CD1 . LEU   B 1 199 ? -13.259 -31.683 24.977  1.00 46.90  ? 185 LEU   F CD1 1 
ATOM   3702 C  CD2 . LEU   B 1 199 ? -13.453 -33.547 23.299  1.00 50.24  ? 185 LEU   F CD2 1 
ATOM   3703 N  N   . ALA   B 1 200 ? -18.520 -32.485 23.472  1.00 39.86  ? 186 ALA   F N   1 
ATOM   3704 C  CA  . ALA   B 1 200 ? -19.775 -32.756 24.180  1.00 40.74  ? 186 ALA   F CA  1 
ATOM   3705 C  C   . ALA   B 1 200 ? -20.742 -31.653 23.811  1.00 39.27  ? 186 ALA   F C   1 
ATOM   3706 O  O   . ALA   B 1 200 ? -20.285 -30.637 23.284  1.00 39.37  ? 186 ALA   F O   1 
ATOM   3707 C  CB  . ALA   B 1 200 ? -19.516 -32.820 25.678  1.00 46.20  ? 186 ALA   F CB  1 
ATOM   3708 N  N   . GLU   B 1 201 ? -22.029 -31.836 24.075  1.00 39.84  ? 187 GLU   F N   1 
ATOM   3709 C  CA  . GLU   B 1 201 ? -23.026 -30.770 23.779  1.00 43.19  ? 187 GLU   F CA  1 
ATOM   3710 C  C   . GLU   B 1 201 ? -22.581 -29.418 24.368  1.00 42.31  ? 187 GLU   F C   1 
ATOM   3711 O  O   . GLU   B 1 201 ? -22.335 -29.342 25.579  1.00 36.01  ? 187 GLU   F O   1 
ATOM   3712 C  CB  . GLU   B 1 201 ? -24.392 -31.174 24.332  1.00 47.08  ? 187 GLU   F CB  1 
ATOM   3713 C  CG  . GLU   B 1 201 ? -25.499 -30.300 23.797  1.00 53.06  ? 187 GLU   F CG  1 
ATOM   3714 C  CD  . GLU   B 1 201 ? -26.823 -30.577 24.467  1.00 56.41  ? 187 GLU   F CD  1 
ATOM   3715 O  OE1 . GLU   B 1 201 ? -26.925 -31.624 25.135  1.00 56.33  ? 187 GLU   F OE1 1 
ATOM   3716 O  OE2 . GLU   B 1 201 ? -27.725 -29.739 24.326  1.00 63.01  ? 187 GLU   F OE2 1 
ATOM   3717 N  N   . GLY   B 1 202 ? -22.475 -28.397 23.516  1.00 37.72  ? 188 GLY   F N   1 
ATOM   3718 C  CA  . GLY   B 1 202 ? -22.053 -27.032 23.871  1.00 40.66  ? 188 GLY   F CA  1 
ATOM   3719 C  C   . GLY   B 1 202 ? -20.599 -26.904 24.296  1.00 38.69  ? 188 GLY   F C   1 
ATOM   3720 O  O   . GLY   B 1 202 ? -20.319 -25.913 24.956  1.00 39.77  ? 188 GLY   F O   1 
ATOM   3721 N  N   . VAL   B 1 203 ? -19.713 -27.856 23.959  1.00 35.95  ? 189 VAL   F N   1 
ATOM   3722 C  CA  . VAL   B 1 203 ? -18.263 -27.761 24.274  1.00 37.37  ? 189 VAL   F CA  1 
ATOM   3723 C  C   . VAL   B 1 203 ? -17.437 -28.126 23.030  1.00 38.20  ? 189 VAL   F C   1 
ATOM   3724 O  O   . VAL   B 1 203 ? -17.479 -29.300 22.555  1.00 36.37  ? 189 VAL   F O   1 
ATOM   3725 C  CB  . VAL   B 1 203 ? -17.835 -28.621 25.471  1.00 38.88  ? 189 VAL   F CB  1 
ATOM   3726 C  CG1 . VAL   B 1 203 ? -16.368 -28.390 25.773  1.00 38.62  ? 189 VAL   F CG1 1 
ATOM   3727 C  CG2 . VAL   B 1 203 ? -18.681 -28.327 26.711  1.00 37.79  ? 189 VAL   F CG2 1 
ATOM   3728 N  N   . LYS   B 1 204 ? -16.678 -27.143 22.569  1.00 35.48  ? 190 LYS   F N   1 
ATOM   3729 C  CA  . LYS   B 1 204 ? -15.941 -27.190 21.295  1.00 40.06  ? 190 LYS   F CA  1 
ATOM   3730 C  C   . LYS   B 1 204 ? -14.491 -26.839 21.631  1.00 33.04  ? 190 LYS   F C   1 
ATOM   3731 O  O   . LYS   B 1 204 ? -14.290 -25.751 22.210  1.00 33.72  ? 190 LYS   F O   1 
ATOM   3732 C  CB  . LYS   B 1 204 ? -16.620 -26.188 20.348  1.00 41.10  ? 190 LYS   F CB  1 
ATOM   3733 C  CG  . LYS   B 1 204 ? -16.212 -26.257 18.889  1.00 54.29  ? 190 LYS   F CG  1 
ATOM   3734 C  CD  . LYS   B 1 204 ? -16.548 -25.032 18.050  1.00 57.70  ? 190 LYS   F CD  1 
ATOM   3735 C  CE  . LYS   B 1 204 ? -18.030 -24.823 17.867  1.00 68.78  ? 190 LYS   F CE  1 
ATOM   3736 N  NZ  . LYS   B 1 204 ? -18.267 -23.799 16.826  1.00 72.18  ? 190 LYS   F NZ  1 
ATOM   3737 N  N   . VAL   B 1 205 ? -13.532 -27.648 21.163  1.00 33.56  ? 191 VAL   F N   1 
ATOM   3738 C  CA  . VAL   B 1 205 ? -12.094 -27.280 21.201  1.00 32.86  ? 191 VAL   F CA  1 
ATOM   3739 C  C   . VAL   B 1 205 ? -11.823 -26.374 20.000  1.00 32.32  ? 191 VAL   F C   1 
ATOM   3740 O  O   . VAL   B 1 205 ? -12.044 -26.821 18.841  1.00 33.86  ? 191 VAL   F O   1 
ATOM   3741 C  CB  . VAL   B 1 205 ? -11.175 -28.520 21.187  1.00 37.99  ? 191 VAL   F CB  1 
ATOM   3742 C  CG1 . VAL   B 1 205 ? -9.719  -28.085 21.298  1.00 42.16  ? 191 VAL   F CG1 1 
ATOM   3743 C  CG2 . VAL   B 1 205 ? -11.539 -29.511 22.285  1.00 35.24  ? 191 VAL   F CG2 1 
ATOM   3744 N  N   . LEU   B 1 206 ? -11.279 -25.200 20.243  1.00 32.53  ? 192 LEU   F N   1 
ATOM   3745 C  CA  . LEU   B 1 206 ? -10.813 -24.269 19.175  1.00 32.34  ? 192 LEU   F CA  1 
ATOM   3746 C  C   . LEU   B 1 206 ? -9.324  -24.501 18.890  1.00 32.46  ? 192 LEU   F C   1 
ATOM   3747 O  O   . LEU   B 1 206 ? -8.489  -24.451 19.811  1.00 34.86  ? 192 LEU   F O   1 
ATOM   3748 C  CB  . LEU   B 1 206 ? -11.036 -22.841 19.641  1.00 32.71  ? 192 LEU   F CB  1 
ATOM   3749 C  CG  . LEU   B 1 206 ? -12.492 -22.537 20.017  1.00 38.82  ? 192 LEU   F CG  1 
ATOM   3750 C  CD1 . LEU   B 1 206 ? -12.603 -21.180 20.690  1.00 38.39  ? 192 LEU   F CD1 1 
ATOM   3751 C  CD2 . LEU   B 1 206 ? -13.387 -22.590 18.784  1.00 42.35  ? 192 LEU   F CD2 1 
ATOM   3752 N  N   . ASN   B 1 207 ? -8.972  -24.725 17.646  1.00 32.01  ? 193 ASN   F N   1 
ATOM   3753 C  CA  . ASN   B 1 207 ? -7.556  -24.833 17.246  1.00 33.30  ? 193 ASN   F CA  1 
ATOM   3754 C  C   . ASN   B 1 207 ? -7.029  -23.444 16.877  1.00 34.41  ? 193 ASN   F C   1 
ATOM   3755 O  O   . ASN   B 1 207 ? -7.234  -22.995 15.730  1.00 32.08  ? 193 ASN   F O   1 
ATOM   3756 C  CB  . ASN   B 1 207 ? -7.402  -25.806 16.087  1.00 38.33  ? 193 ASN   F CB  1 
ATOM   3757 C  CG  . ASN   B 1 207 ? -5.945  -26.059 15.738  1.00 33.16  ? 193 ASN   F CG  1 
ATOM   3758 O  OD1 . ASN   B 1 207 ? -5.054  -25.395 16.249  1.00 33.46  ? 193 ASN   F OD1 1 
ATOM   3759 N  ND2 . ASN   B 1 207 ? -5.721  -26.925 14.780  1.00 38.26  ? 193 ASN   F ND2 1 
ATOM   3760 N  N   . PHE   B 1 208 ? -6.356  -22.769 17.802  1.00 32.10  ? 194 PHE   F N   1 
ATOM   3761 C  CA  . PHE   B 1 208 ? -5.797  -21.415 17.559  1.00 34.81  ? 194 PHE   F CA  1 
ATOM   3762 C  C   . PHE   B 1 208 ? -4.504  -21.482 16.730  1.00 35.64  ? 194 PHE   F C   1 
ATOM   3763 O  O   . PHE   B 1 208 ? -4.160  -20.491 16.099  1.00 36.31  ? 194 PHE   F O   1 
ATOM   3764 C  CB  . PHE   B 1 208 ? -5.574  -20.651 18.863  1.00 34.55  ? 194 PHE   F CB  1 
ATOM   3765 C  CG  . PHE   B 1 208 ? -6.829  -20.306 19.627  1.00 33.30  ? 194 PHE   F CG  1 
ATOM   3766 C  CD1 . PHE   B 1 208 ? -8.015  -19.945 18.979  1.00 33.33  ? 194 PHE   F CD1 1 
ATOM   3767 C  CD2 . PHE   B 1 208 ? -6.808  -20.281 21.008  1.00 35.24  ? 194 PHE   F CD2 1 
ATOM   3768 C  CE1 . PHE   B 1 208 ? -9.151  -19.615 19.698  1.00 30.78  ? 194 PHE   F CE1 1 
ATOM   3769 C  CE2 . PHE   B 1 208 ? -7.939  -19.926 21.722  1.00 34.15  ? 194 PHE   F CE2 1 
ATOM   3770 C  CZ  . PHE   B 1 208 ? -9.098  -19.580 21.073  1.00 35.01  ? 194 PHE   F CZ  1 
ATOM   3771 N  N   . GLY   B 1 209 ? -3.802  -22.609 16.755  1.00 36.55  ? 195 GLY   F N   1 
ATOM   3772 C  CA  . GLY   B 1 209 ? -2.514  -22.786 16.079  1.00 39.44  ? 195 GLY   F CA  1 
ATOM   3773 C  C   . GLY   B 1 209 ? -1.386  -22.035 16.772  1.00 35.48  ? 195 GLY   F C   1 
ATOM   3774 O  O   . GLY   B 1 209 ? -1.501  -21.729 17.994  1.00 34.90  ? 195 GLY   F O   1 
ATOM   3775 N  N   . SER   B 1 210 ? -0.302  -21.761 16.033  1.00 33.06  ? 196 SER   F N   1 
ATOM   3776 C  CA  . SER   B 1 210 ? 0.961   -21.177 16.567  1.00 32.09  ? 196 SER   F CA  1 
ATOM   3777 C  C   . SER   B 1 210 ? 0.712   -19.707 16.916  1.00 31.28  ? 196 SER   F C   1 
ATOM   3778 O  O   . SER   B 1 210 ? -0.114  -19.055 16.245  1.00 31.83  ? 196 SER   F O   1 
ATOM   3779 C  CB  . SER   B 1 210 ? 2.106   -21.326 15.577  1.00 31.42  ? 196 SER   F CB  1 
ATOM   3780 O  OG  . SER   B 1 210 ? 1.671   -20.957 14.277  1.00 34.61  ? 196 SER   F OG  1 
ATOM   3781 N  N   . GLY   B 1 211 ? 1.352   -19.222 17.966  1.00 30.80  ? 197 GLY   F N   1 
ATOM   3782 C  CA  . GLY   B 1 211 ? 1.270   -17.818 18.373  1.00 34.76  ? 197 GLY   F CA  1 
ATOM   3783 C  C   . GLY   B 1 211 ? 2.111   -17.631 19.601  1.00 32.81  ? 197 GLY   F C   1 
ATOM   3784 O  O   . GLY   B 1 211 ? 3.333   -17.646 19.491  1.00 31.63  ? 197 GLY   F O   1 
ATOM   3785 N  N   . HIS   B 1 212 ? 1.475   -17.613 20.768  1.00 30.60  ? 198 HIS   F N   1 
ATOM   3786 C  CA  . HIS   B 1 212 ? 2.187   -17.606 22.062  1.00 33.04  ? 198 HIS   F CA  1 
ATOM   3787 C  C   . HIS   B 1 212 ? 3.179   -18.782 22.128  1.00 34.69  ? 198 HIS   F C   1 
ATOM   3788 O  O   . HIS   B 1 212 ? 4.288   -18.542 22.493  1.00 33.82  ? 198 HIS   F O   1 
ATOM   3789 C  CB  . HIS   B 1 212 ? 1.180   -17.683 23.206  1.00 33.85  ? 198 HIS   F CB  1 
ATOM   3790 C  CG  . HIS   B 1 212 ? 1.772   -17.966 24.539  1.00 31.19  ? 198 HIS   F CG  1 
ATOM   3791 N  ND1 . HIS   B 1 212 ? 2.446   -16.981 25.247  1.00 32.09  ? 198 HIS   F ND1 1 
ATOM   3792 C  CD2 . HIS   B 1 212 ? 1.745   -19.067 25.326  1.00 34.16  ? 198 HIS   F CD2 1 
ATOM   3793 C  CE1 . HIS   B 1 212 ? 2.825   -17.478 26.424  1.00 33.61  ? 198 HIS   F CE1 1 
ATOM   3794 N  NE2 . HIS   B 1 212 ? 2.401   -18.759 26.512  1.00 35.56  ? 198 HIS   F NE2 1 
ATOM   3795 N  N   . ALA   B 1 213 ? 2.743   -19.998 21.788  1.00 32.31  ? 199 ALA   F N   1 
ATOM   3796 C  CA  . ALA   B 1 213 ? 3.598   -21.200 21.789  1.00 33.41  ? 199 ALA   F CA  1 
ATOM   3797 C  C   . ALA   B 1 213 ? 3.445   -21.894 20.435  1.00 30.77  ? 199 ALA   F C   1 
ATOM   3798 O  O   . ALA   B 1 213 ? 2.855   -21.279 19.491  1.00 31.47  ? 199 ALA   F O   1 
ATOM   3799 C  CB  . ALA   B 1 213 ? 3.280   -22.063 23.002  1.00 32.97  ? 199 ALA   F CB  1 
ATOM   3800 N  N   . TRP   B 1 214 ? 3.983   -23.102 20.297  1.00 32.26  ? 200 TRP   F N   1 
ATOM   3801 C  CA  . TRP   B 1 214 ? 3.939   -23.875 19.025  1.00 33.16  ? 200 TRP   F CA  1 
ATOM   3802 C  C   . TRP   B 1 214 ? 2.503   -24.152 18.608  1.00 33.43  ? 200 TRP   F C   1 
ATOM   3803 O  O   . TRP   B 1 214 ? 2.212   -24.142 17.414  1.00 31.79  ? 200 TRP   F O   1 
ATOM   3804 C  CB  . TRP   B 1 214 ? 4.743   -25.176 19.126  1.00 33.06  ? 200 TRP   F CB  1 
ATOM   3805 C  CG  . TRP   B 1 214 ? 6.203   -24.966 19.360  1.00 36.50  ? 200 TRP   F CG  1 
ATOM   3806 C  CD1 . TRP   B 1 214 ? 7.059   -24.299 18.533  1.00 41.05  ? 200 TRP   F CD1 1 
ATOM   3807 C  CD2 . TRP   B 1 214 ? 6.998   -25.437 20.466  1.00 36.29  ? 200 TRP   F CD2 1 
ATOM   3808 N  NE1 . TRP   B 1 214 ? 8.319   -24.285 19.068  1.00 42.80  ? 200 TRP   F NE1 1 
ATOM   3809 C  CE2 . TRP   B 1 214 ? 8.321   -24.992 20.237  1.00 40.46  ? 200 TRP   F CE2 1 
ATOM   3810 C  CE3 . TRP   B 1 214 ? 6.730   -26.188 21.621  1.00 37.97  ? 200 TRP   F CE3 1 
ATOM   3811 C  CZ2 . TRP   B 1 214 ? 9.371   -25.279 21.110  1.00 40.80  ? 200 TRP   F CZ2 1 
ATOM   3812 C  CZ3 . TRP   B 1 214 ? 7.769   -26.497 22.466  1.00 36.47  ? 200 TRP   F CZ3 1 
ATOM   3813 C  CH2 . TRP   B 1 214 ? 9.068   -26.039 22.218  1.00 38.25  ? 200 TRP   F CH2 1 
ATOM   3814 N  N   . GLY   B 1 215 ? 1.610   -24.462 19.544  1.00 29.52  ? 201 GLY   F N   1 
ATOM   3815 C  CA  . GLY   B 1 215 ? 0.234   -24.784 19.162  1.00 33.04  ? 201 GLY   F CA  1 
ATOM   3816 C  C   . GLY   B 1 215 ? -0.728  -24.564 20.309  1.00 32.95  ? 201 GLY   F C   1 
ATOM   3817 O  O   . GLY   B 1 215 ? -0.583  -25.210 21.348  1.00 32.05  ? 201 GLY   F O   1 
ATOM   3818 N  N   . MET   B 1 216 ? -1.672  -23.667 20.126  1.00 31.15  ? 202 MET   F N   1 
ATOM   3819 C  CA  . MET   B 1 216 ? -2.547  -23.222 21.219  1.00 33.21  ? 202 MET   F CA  1 
ATOM   3820 C  C   . MET   B 1 216 ? -3.944  -23.836 20.988  1.00 32.73  ? 202 MET   F C   1 
ATOM   3821 O  O   . MET   B 1 216 ? -4.496  -23.715 19.862  1.00 31.55  ? 202 MET   F O   1 
ATOM   3822 C  CB  . MET   B 1 216 ? -2.655  -21.692 21.259  1.00 32.33  ? 202 MET   F CB  1 
ATOM   3823 C  CG  . MET   B 1 216 ? -1.313  -20.964 21.357  1.00 35.72  ? 202 MET   F CG  1 
ATOM   3824 S  SD  . MET   B 1 216 ? -0.430  -21.340 22.897  1.00 37.10  ? 202 MET   F SD  1 
ATOM   3825 C  CE  . MET   B 1 216 ? -1.500  -20.641 24.151  1.00 36.71  ? 202 MET   F CE  1 
ATOM   3826 N  N   . LEU   B 1 217 ? -4.574  -24.333 22.053  1.00 29.26  ? 203 LEU   F N   1 
ATOM   3827 C  CA  . LEU   B 1 217 ? -6.004  -24.699 21.985  1.00 28.87  ? 203 LEU   F CA  1 
ATOM   3828 C  C   . LEU   B 1 217 ? -6.807  -23.831 22.934  1.00 32.86  ? 203 LEU   F C   1 
ATOM   3829 O  O   . LEU   B 1 217 ? -6.317  -23.480 24.046  1.00 30.62  ? 203 LEU   F O   1 
ATOM   3830 C  CB  . LEU   B 1 217 ? -6.213  -26.171 22.302  1.00 28.83  ? 203 LEU   F CB  1 
ATOM   3831 C  CG  . LEU   B 1 217 ? -5.393  -27.164 21.485  1.00 32.01  ? 203 LEU   F CG  1 
ATOM   3832 C  CD1 . LEU   B 1 217 ? -5.616  -28.571 22.043  1.00 33.16  ? 203 LEU   F CD1 1 
ATOM   3833 C  CD2 . LEU   B 1 217 ? -5.768  -27.096 20.019  1.00 31.28  ? 203 LEU   F CD2 1 
ATOM   3834 N  N   . GLY   B 1 218 ? -8.006  -23.535 22.493  1.00 34.10  ? 204 GLY   F N   1 
ATOM   3835 C  CA  . GLY   B 1 218 ? -8.983  -22.861 23.325  1.00 30.05  ? 204 GLY   F CA  1 
ATOM   3836 C  C   . GLY   B 1 218 ? -10.189 -23.725 23.511  1.00 31.33  ? 204 GLY   F C   1 
ATOM   3837 O  O   . GLY   B 1 218 ? -10.248 -24.784 22.894  1.00 32.97  ? 204 GLY   F O   1 
ATOM   3838 N  N   . LEU   B 1 219 ? -11.182 -23.203 24.251  1.00 31.01  ? 205 LEU   F N   1 
ATOM   3839 C  CA  . LEU   B 1 219 ? -12.474 -23.883 24.448  1.00 34.37  ? 205 LEU   F CA  1 
ATOM   3840 C  C   . LEU   B 1 219 ? -13.603 -22.867 24.252  1.00 35.03  ? 205 LEU   F C   1 
ATOM   3841 O  O   . LEU   B 1 219 ? -13.455 -21.732 24.720  1.00 32.15  ? 205 LEU   F O   1 
ATOM   3842 C  CB  . LEU   B 1 219 ? -12.517 -24.489 25.847  1.00 35.48  ? 205 LEU   F CB  1 
ATOM   3843 C  CG  . LEU   B 1 219 ? -13.251 -25.814 25.959  1.00 38.63  ? 205 LEU   F CG  1 
ATOM   3844 C  CD1 . LEU   B 1 219 ? -12.575 -26.932 25.148  1.00 37.60  ? 205 LEU   F CD1 1 
ATOM   3845 C  CD2 . LEU   B 1 219 ? -13.364 -26.212 27.435  1.00 41.66  ? 205 LEU   F CD2 1 
ATOM   3846 N  N   . HIS   B 1 220 ? -14.625 -23.262 23.512  1.00 29.70  ? 206 HIS   F N   1 
ATOM   3847 C  CA  . HIS   B 1 220 ? -15.881 -22.488 23.429  1.00 31.71  ? 206 HIS   F CA  1 
ATOM   3848 C  C   . HIS   B 1 220 ? -16.939 -23.321 24.149  1.00 34.61  ? 206 HIS   F C   1 
ATOM   3849 O  O   . HIS   B 1 220 ? -17.213 -24.474 23.734  1.00 35.79  ? 206 HIS   F O   1 
ATOM   3850 C  CB  . HIS   B 1 220 ? -16.282 -22.080 22.016  1.00 37.64  ? 206 HIS   F CB  1 
ATOM   3851 C  CG  . HIS   B 1 220 ? -17.439 -21.143 22.102  1.00 47.81  ? 206 HIS   F CG  1 
ATOM   3852 N  ND1 . HIS   B 1 220 ? -18.743 -21.604 22.346  1.00 63.55  ? 206 HIS   F ND1 1 
ATOM   3853 C  CD2 . HIS   B 1 220 ? -17.498 -19.800 22.192  1.00 49.64  ? 206 HIS   F CD2 1 
ATOM   3854 C  CE1 . HIS   B 1 220 ? -19.551 -20.563 22.480  1.00 58.23  ? 206 HIS   F CE1 1 
ATOM   3855 N  NE2 . HIS   B 1 220 ? -18.793 -19.444 22.384  1.00 51.16  ? 206 HIS   F NE2 1 
ATOM   3856 N  N   . VAL   B 1 221 ? -17.467 -22.768 25.231  1.00 37.49  ? 207 VAL   F N   1 
ATOM   3857 C  CA  . VAL   B 1 221 ? -18.491 -23.446 26.063  1.00 33.79  ? 207 VAL   F CA  1 
ATOM   3858 C  C   . VAL   B 1 221 ? -19.797 -22.653 25.936  1.00 35.11  ? 207 VAL   F C   1 
ATOM   3859 O  O   . VAL   B 1 221 ? -19.786 -21.423 26.181  1.00 35.29  ? 207 VAL   F O   1 
ATOM   3860 C  CB  . VAL   B 1 221 ? -18.021 -23.518 27.526  1.00 38.19  ? 207 VAL   F CB  1 
ATOM   3861 C  CG1 . VAL   B 1 221 ? -19.043 -24.245 28.388  1.00 38.89  ? 207 VAL   F CG1 1 
ATOM   3862 C  CG2 . VAL   B 1 221 ? -16.672 -24.206 27.637  1.00 42.87  ? 207 VAL   F CG2 1 
ATOM   3863 N  N   . GLU   B 1 222 ? -20.891 -23.350 25.662  1.00 31.88  ? 208 GLU   F N   1 
ATOM   3864 C  CA  . GLU   B 1 222 ? -22.241 -22.726 25.593  1.00 40.21  ? 208 GLU   F CA  1 
ATOM   3865 C  C   . GLU   B 1 222 ? -23.038 -23.236 26.805  1.00 39.18  ? 208 GLU   F C   1 
ATOM   3866 O  O   . GLU   B 1 222 ? -23.401 -24.415 26.829  1.00 37.41  ? 208 GLU   F O   1 
ATOM   3867 C  CB  . GLU   B 1 222 ? -22.917 -23.028 24.246  1.00 39.43  ? 208 GLU   F CB  1 
ATOM   3868 C  CG  . GLU   B 1 222 ? -24.231 -22.258 24.066  1.00 51.46  ? 208 GLU   F CG  1 
ATOM   3869 C  CD  . GLU   B 1 222 ? -24.008 -20.759 23.935  1.00 51.32  ? 208 GLU   F CD  1 
ATOM   3870 O  OE1 . GLU   B 1 222 ? -22.973 -20.387 23.348  1.00 57.77  ? 208 GLU   F OE1 1 
ATOM   3871 O  OE2 . GLU   B 1 222 ? -24.848 -19.982 24.433  1.00 58.79  ? 208 GLU   F OE2 1 
ATOM   3872 N  N   . LEU   B 1 223 ? -23.294 -22.378 27.774  1.00 41.17  ? 209 LEU   F N   1 
ATOM   3873 C  CA  . LEU   B 1 223 ? -24.034 -22.785 28.996  1.00 43.50  ? 209 LEU   F CA  1 
ATOM   3874 C  C   . LEU   B 1 223 ? -25.466 -22.260 28.875  1.00 39.43  ? 209 LEU   F C   1 
ATOM   3875 O  O   . LEU   B 1 223 ? -25.646 -21.115 28.501  1.00 41.92  ? 209 LEU   F O   1 
ATOM   3876 C  CB  . LEU   B 1 223 ? -23.332 -22.200 30.223  1.00 43.39  ? 209 LEU   F CB  1 
ATOM   3877 C  CG  . LEU   B 1 223 ? -21.950 -22.760 30.558  1.00 44.24  ? 209 LEU   F CG  1 
ATOM   3878 C  CD1 . LEU   B 1 223 ? -21.376 -22.010 31.730  1.00 45.25  ? 209 LEU   F CD1 1 
ATOM   3879 C  CD2 . LEU   B 1 223 ? -22.009 -24.259 30.842  1.00 45.58  ? 209 LEU   F CD2 1 
ATOM   3880 N  N   . PRO   B 1 224 ? -26.492 -23.062 29.231  1.00 40.82  ? 210 PRO   F N   1 
ATOM   3881 C  CA  . PRO   B 1 224 ? -27.894 -22.632 29.184  1.00 47.18  ? 210 PRO   F CA  1 
ATOM   3882 C  C   . PRO   B 1 224 ? -28.211 -21.326 29.916  1.00 46.02  ? 210 PRO   F C   1 
ATOM   3883 O  O   . PRO   B 1 224 ? -28.930 -20.562 29.354  1.00 50.15  ? 210 PRO   F O   1 
ATOM   3884 C  CB  . PRO   B 1 224 ? -28.660 -23.746 29.911  1.00 49.06  ? 210 PRO   F CB  1 
ATOM   3885 C  CG  . PRO   B 1 224 ? -27.761 -24.961 29.784  1.00 49.73  ? 210 PRO   F CG  1 
ATOM   3886 C  CD  . PRO   B 1 224 ? -26.343 -24.442 29.713  1.00 46.72  ? 210 PRO   F CD  1 
ATOM   3887 N  N   . GLU   B 1 225 ? -27.642 -21.082 31.108  1.00 45.69  ? 211 GLU   F N   1 
ATOM   3888 C  CA  . GLU   B 1 225 ? -27.915 -19.839 31.872  1.00 49.87  ? 211 GLU   F CA  1 
ATOM   3889 C  C   . GLU   B 1 225 ? -26.920 -18.754 31.467  1.00 47.58  ? 211 GLU   F C   1 
ATOM   3890 O  O   . GLU   B 1 225 ? -27.348 -17.635 31.259  1.00 45.05  ? 211 GLU   F O   1 
ATOM   3891 C  CB  . GLU   B 1 225 ? -27.860 -20.057 33.391  1.00 56.99  ? 211 GLU   F CB  1 
ATOM   3892 C  CG  . GLU   B 1 225 ? -28.798 -21.135 33.904  1.00 86.01  ? 211 GLU   F CG  1 
ATOM   3893 C  CD  . GLU   B 1 225 ? -30.275 -20.765 33.972  1.00 110.59 ? 211 GLU   F CD  1 
ATOM   3894 O  OE1 . GLU   B 1 225 ? -31.000 -21.430 34.750  1.00 116.68 ? 211 GLU   F OE1 1 
ATOM   3895 O  OE2 . GLU   B 1 225 ? -30.698 -19.812 33.264  1.00 122.51 ? 211 GLU   F OE2 1 
ATOM   3896 N  N   . THR   B 1 226 ? -25.624 -19.052 31.478  1.00 40.91  ? 212 THR   F N   1 
ATOM   3897 C  CA  . THR   B 1 226 ? -24.561 -18.023 31.440  1.00 41.19  ? 212 THR   F CA  1 
ATOM   3898 C  C   . THR   B 1 226 ? -24.361 -17.591 29.975  1.00 39.87  ? 212 THR   F C   1 
ATOM   3899 O  O   . THR   B 1 226 ? -23.885 -16.456 29.748  1.00 41.47  ? 212 THR   F O   1 
ATOM   3900 C  CB  . THR   B 1 226 ? -23.273 -18.545 32.093  1.00 45.34  ? 212 THR   F CB  1 
ATOM   3901 O  OG1 . THR   B 1 226 ? -23.535 -18.869 33.462  1.00 50.76  ? 212 THR   F OG1 1 
ATOM   3902 C  CG2 . THR   B 1 226 ? -22.137 -17.545 32.048  1.00 45.04  ? 212 THR   F CG2 1 
ATOM   3903 N  N   . GLY   B 1 227 ? -24.719 -18.451 29.024  1.00 39.72  ? 213 GLY   F N   1 
ATOM   3904 C  CA  . GLY   B 1 227 ? -24.451 -18.227 27.587  1.00 39.91  ? 213 GLY   F CA  1 
ATOM   3905 C  C   . GLY   B 1 227 ? -23.032 -18.625 27.226  1.00 41.01  ? 213 GLY   F C   1 
ATOM   3906 O  O   . GLY   B 1 227 ? -22.515 -19.610 27.814  1.00 38.14  ? 213 GLY   F O   1 
ATOM   3907 N  N   . GLY   B 1 228 ? -22.405 -17.941 26.258  1.00 39.58  ? 214 GLY   F N   1 
ATOM   3908 C  CA  . GLY   B 1 228 ? -21.111 -18.390 25.704  1.00 37.38  ? 214 GLY   F CA  1 
ATOM   3909 C  C   . GLY   B 1 228 ? -19.885 -17.924 26.491  1.00 35.31  ? 214 GLY   F C   1 
ATOM   3910 O  O   . GLY   B 1 228 ? -19.804 -16.745 26.956  1.00 33.18  ? 214 GLY   F O   1 
ATOM   3911 N  N   . ILE   B 1 229 ? -18.887 -18.797 26.585  1.00 33.78  ? 215 ILE   F N   1 
ATOM   3912 C  CA  . ILE   B 1 229 ? -17.580 -18.462 27.197  1.00 37.21  ? 215 ILE   F CA  1 
ATOM   3913 C  C   . ILE   B 1 229 ? -16.488 -18.978 26.269  1.00 34.71  ? 215 ILE   F C   1 
ATOM   3914 O  O   . ILE   B 1 229 ? -16.542 -20.199 25.926  1.00 36.68  ? 215 ILE   F O   1 
ATOM   3915 C  CB  . ILE   B 1 229 ? -17.464 -19.107 28.583  1.00 35.99  ? 215 ILE   F CB  1 
ATOM   3916 C  CG1 . ILE   B 1 229 ? -18.560 -18.640 29.556  1.00 40.18  ? 215 ILE   F CG1 1 
ATOM   3917 C  CG2 . ILE   B 1 229 ? -16.056 -18.896 29.137  1.00 40.76  ? 215 ILE   F CG2 1 
ATOM   3918 C  CD1 . ILE   B 1 229 ? -18.665 -19.486 30.805  1.00 42.09  ? 215 ILE   F CD1 1 
ATOM   3919 N  N   . ILE   B 1 230 ? -15.509 -18.116 25.983  1.00 34.19  ? 216 ILE   F N   1 
ATOM   3920 C  CA  . ILE   B 1 230 ? -14.249 -18.531 25.325  1.00 35.10  ? 216 ILE   F CA  1 
ATOM   3921 C  C   . ILE   B 1 230 ? -13.142 -18.594 26.380  1.00 33.35  ? 216 ILE   F C   1 
ATOM   3922 O  O   . ILE   B 1 230 ? -12.855 -17.579 27.007  1.00 33.81  ? 216 ILE   F O   1 
ATOM   3923 C  CB  . ILE   B 1 230 ? -13.907 -17.604 24.151  1.00 36.90  ? 216 ILE   F CB  1 
ATOM   3924 C  CG1 . ILE   B 1 230 ? -15.006 -17.621 23.091  1.00 41.83  ? 216 ILE   F CG1 1 
ATOM   3925 C  CG2 . ILE   B 1 230 ? -12.559 -17.964 23.559  1.00 39.12  ? 216 ILE   F CG2 1 
ATOM   3926 C  CD1 . ILE   B 1 230 ? -14.960 -16.405 22.158  1.00 42.95  ? 216 ILE   F CD1 1 
ATOM   3927 N  N   . LEU   B 1 231 ? -12.505 -19.767 26.537  1.00 33.95  ? 217 LEU   F N   1 
ATOM   3928 C  CA  . LEU   B 1 231 ? -11.280 -19.900 27.341  1.00 32.52  ? 217 LEU   F CA  1 
ATOM   3929 C  C   . LEU   B 1 231 ? -10.122 -19.701 26.385  1.00 33.26  ? 217 LEU   F C   1 
ATOM   3930 O  O   . LEU   B 1 231 ? -9.917  -20.585 25.520  1.00 32.49  ? 217 LEU   F O   1 
ATOM   3931 C  CB  . LEU   B 1 231 ? -11.241 -21.275 28.014  1.00 35.48  ? 217 LEU   F CB  1 
ATOM   3932 C  CG  . LEU   B 1 231 ? -12.481 -21.610 28.837  1.00 36.95  ? 217 LEU   F CG  1 
ATOM   3933 C  CD1 . LEU   B 1 231 ? -12.335 -22.965 29.514  1.00 39.90  ? 217 LEU   F CD1 1 
ATOM   3934 C  CD2 . LEU   B 1 231 ? -12.786 -20.511 29.853  1.00 36.15  ? 217 LEU   F CD2 1 
ATOM   3935 N  N   . ALA   B 1 232 ? -9.453  -18.559 26.503  1.00 33.45  ? 218 ALA   F N   1 
ATOM   3936 C  CA  . ALA   B 1 232 ? -8.376  -18.120 25.586  1.00 35.74  ? 218 ALA   F CA  1 
ATOM   3937 C  C   . ALA   B 1 232 ? -7.023  -18.640 26.065  1.00 37.92  ? 218 ALA   F C   1 
ATOM   3938 O  O   . ALA   B 1 232 ? -6.095  -18.700 25.227  1.00 34.58  ? 218 ALA   F O   1 
ATOM   3939 C  CB  . ALA   B 1 232 ? -8.363  -16.618 25.527  1.00 36.68  ? 218 ALA   F CB  1 
ATOM   3940 N  N   . SER   B 1 233 ? -6.891  -18.886 27.377  1.00 34.46  ? 219 SER   F N   1 
ATOM   3941 C  CA  . SER   B 1 233 ? -5.601  -19.178 28.038  1.00 35.98  ? 219 SER   F CA  1 
ATOM   3942 C  C   . SER   B 1 233 ? -4.552  -18.141 27.562  1.00 36.31  ? 219 SER   F C   1 
ATOM   3943 O  O   . SER   B 1 233 ? -4.880  -16.934 27.418  1.00 33.30  ? 219 SER   F O   1 
ATOM   3944 C  CB  . SER   B 1 233 ? -5.207  -20.625 27.718  1.00 37.06  ? 219 SER   F CB  1 
ATOM   3945 O  OG  . SER   B 1 233 ? -3.988  -20.983 28.343  1.00 35.28  ? 219 SER   F OG  1 
ATOM   3946 N  N   . ASP   B 1 234 ? -3.346  -18.575 27.210  1.00 32.26  ? 220 ASP   F N   1 
ATOM   3947 C  CA  . ASP   B 1 234 ? -2.254  -17.612 26.882  1.00 34.07  ? 220 ASP   F CA  1 
ATOM   3948 C  C   . ASP   B 1 234 ? -2.327  -17.089 25.444  1.00 32.45  ? 220 ASP   F C   1 
ATOM   3949 O  O   . ASP   B 1 234 ? -1.406  -16.325 25.076  1.00 34.82  ? 220 ASP   F O   1 
ATOM   3950 C  CB  . ASP   B 1 234 ? -0.879  -18.197 27.187  1.00 33.95  ? 220 ASP   F CB  1 
ATOM   3951 C  CG  . ASP   B 1 234 ? -0.597  -18.280 28.688  1.00 37.53  ? 220 ASP   F CG  1 
ATOM   3952 O  OD1 . ASP   B 1 234 ? -1.468  -17.849 29.472  1.00 39.02  ? 220 ASP   F OD1 1 
ATOM   3953 O  OD2 . ASP   B 1 234 ? 0.393   -18.887 28.999  1.00 39.60  ? 220 ASP   F OD2 1 
ATOM   3954 N  N   . ALA   B 1 235 ? -3.345  -17.420 24.671  1.00 33.98  ? 221 ALA   F N   1 
ATOM   3955 C  CA  . ALA   B 1 235 ? -3.637  -16.676 23.423  1.00 32.94  ? 221 ALA   F CA  1 
ATOM   3956 C  C   . ALA   B 1 235 ? -3.843  -15.189 23.778  1.00 33.53  ? 221 ALA   F C   1 
ATOM   3957 O  O   . ALA   B 1 235 ? -3.512  -14.323 22.947  1.00 32.99  ? 221 ALA   F O   1 
ATOM   3958 C  CB  . ALA   B 1 235 ? -4.825  -17.241 22.722  1.00 29.27  ? 221 ALA   F CB  1 
ATOM   3959 N  N   . ILE   B 1 236 ? -4.368  -14.896 24.982  1.00 34.38  ? 222 ILE   F N   1 
ATOM   3960 C  CA  . ILE   B 1 236 ? -4.566  -13.498 25.467  1.00 33.46  ? 222 ILE   F CA  1 
ATOM   3961 C  C   . ILE   B 1 236 ? -4.276  -13.442 26.965  1.00 35.52  ? 222 ILE   F C   1 
ATOM   3962 O  O   . ILE   B 1 236 ? -5.110  -13.881 27.751  1.00 31.77  ? 222 ILE   F O   1 
ATOM   3963 C  CB  . ILE   B 1 236 ? -5.986  -12.961 25.184  1.00 36.92  ? 222 ILE   F CB  1 
ATOM   3964 C  CG1 . ILE   B 1 236 ? -6.462  -13.275 23.768  1.00 37.04  ? 222 ILE   F CG1 1 
ATOM   3965 C  CG2 . ILE   B 1 236 ? -6.050  -11.455 25.494  1.00 38.54  ? 222 ILE   F CG2 1 
ATOM   3966 C  CD1 . ILE   B 1 236 ? -7.967  -13.016 23.536  1.00 38.27  ? 222 ILE   F CD1 1 
ATOM   3967 N  N   . TYR   B 1 237 ? -3.149  -12.876 27.361  1.00 34.11  ? 223 TYR   F N   1 
ATOM   3968 C  CA  . TYR   B 1 237 ? -2.754  -12.818 28.788  1.00 36.39  ? 223 TYR   F CA  1 
ATOM   3969 C  C   . TYR   B 1 237 ? -3.789  -12.029 29.629  1.00 36.87  ? 223 TYR   F C   1 
ATOM   3970 O  O   . TYR   B 1 237 ? -4.161  -12.502 30.729  1.00 35.82  ? 223 TYR   F O   1 
ATOM   3971 C  CB  . TYR   B 1 237 ? -1.369  -12.176 28.895  1.00 36.27  ? 223 TYR   F CB  1 
ATOM   3972 C  CG  . TYR   B 1 237 ? -0.156  -13.058 28.765  1.00 33.42  ? 223 TYR   F CG  1 
ATOM   3973 C  CD1 . TYR   B 1 237 ? -0.177  -14.388 29.113  1.00 32.98  ? 223 TYR   F CD1 1 
ATOM   3974 C  CD2 . TYR   B 1 237 ? 1.067   -12.498 28.421  1.00 34.29  ? 223 TYR   F CD2 1 
ATOM   3975 C  CE1 . TYR   B 1 237 ? 0.961   -15.183 29.059  1.00 35.10  ? 223 TYR   F CE1 1 
ATOM   3976 C  CE2 . TYR   B 1 237 ? 2.231   -13.269 28.413  1.00 36.86  ? 223 TYR   F CE2 1 
ATOM   3977 C  CZ  . TYR   B 1 237 ? 2.178   -14.614 28.751  1.00 35.69  ? 223 TYR   F CZ  1 
ATOM   3978 O  OH  . TYR   B 1 237 ? 3.287   -15.405 28.747  1.00 35.88  ? 223 TYR   F OH  1 
ATOM   3979 N  N   . THR   B 1 238 ? -4.183  -10.826 29.189  1.00 32.72  ? 224 THR   F N   1 
ATOM   3980 C  CA  . THR   B 1 238 ? -4.945  -9.850  30.021  1.00 36.43  ? 224 THR   F CA  1 
ATOM   3981 C  C   . THR   B 1 238 ? -5.761  -8.938  29.116  1.00 38.06  ? 224 THR   F C   1 
ATOM   3982 O  O   . THR   B 1 238 ? -5.536  -8.937  27.916  1.00 36.21  ? 224 THR   F O   1 
ATOM   3983 C  CB  . THR   B 1 238 ? -4.020  -8.938  30.862  1.00 39.22  ? 224 THR   F CB  1 
ATOM   3984 O  OG1 . THR   B 1 238 ? -3.345  -8.013  29.998  1.00 40.02  ? 224 THR   F OG1 1 
ATOM   3985 C  CG2 . THR   B 1 238 ? -2.959  -9.690  31.634  1.00 40.21  ? 224 THR   F CG2 1 
ATOM   3986 N  N   . ALA   B 1 239 ? -6.621  -8.127  29.720  1.00 35.59  ? 225 ALA   F N   1 
ATOM   3987 C  CA  . ALA   B 1 239 ? -7.452  -7.099  29.071  1.00 38.70  ? 225 ALA   F CA  1 
ATOM   3988 C  C   . ALA   B 1 239 ? -6.542  -6.089  28.372  1.00 36.87  ? 225 ALA   F C   1 
ATOM   3989 O  O   . ALA   B 1 239 ? -6.949  -5.559  27.305  1.00 38.61  ? 225 ALA   F O   1 
ATOM   3990 C  CB  . ALA   B 1 239 ? -8.422  -6.459  30.084  1.00 37.49  ? 225 ALA   F CB  1 
ATOM   3991 N  N   . GLU   B 1 240 ? -5.381  -5.820  28.937  1.00 39.29  ? 226 GLU   F N   1 
ATOM   3992 C  CA  . GLU   B 1 240 ? -4.396  -4.888  28.327  1.00 41.94  ? 226 GLU   F CA  1 
ATOM   3993 C  C   . GLU   B 1 240 ? -3.834  -5.513  27.017  1.00 42.01  ? 226 GLU   F C   1 
ATOM   3994 O  O   . GLU   B 1 240 ? -3.698  -4.787  26.008  1.00 40.74  ? 226 GLU   F O   1 
ATOM   3995 C  CB  . GLU   B 1 240 ? -3.326  -4.560  29.377  1.00 43.68  ? 226 GLU   F CB  1 
ATOM   3996 C  CG  . GLU   B 1 240 ? -2.252  -3.609  28.839  1.00 50.88  ? 226 GLU   F CG  1 
ATOM   3997 C  CD  . GLU   B 1 240 ? -1.147  -3.149  29.786  1.00 56.03  ? 226 GLU   F CD  1 
ATOM   3998 O  OE1 . GLU   B 1 240 ? -0.969  -3.756  30.860  1.00 49.61  ? 226 GLU   F OE1 1 
ATOM   3999 O  OE2 . GLU   B 1 240 ? -0.455  -2.178  29.426  1.00 56.46  ? 226 GLU   F OE2 1 
ATOM   4000 N  N   . SER   B 1 241 ? -3.526  -6.824  27.012  1.00 39.45  ? 227 SER   F N   1 
ATOM   4001 C  CA  . SER   B 1 241 ? -3.128  -7.583  25.793  1.00 38.84  ? 227 SER   F CA  1 
ATOM   4002 C  C   . SER   B 1 241 ? -4.216  -7.384  24.726  1.00 36.41  ? 227 SER   F C   1 
ATOM   4003 O  O   . SER   B 1 241 ? -3.920  -7.128  23.537  1.00 34.73  ? 227 SER   F O   1 
ATOM   4004 C  CB  . SER   B 1 241 ? -2.919  -9.072  26.093  1.00 36.48  ? 227 SER   F CB  1 
ATOM   4005 O  OG  . SER   B 1 241 ? -2.112  -9.282  27.265  1.00 35.52  ? 227 SER   F OG  1 
ATOM   4006 N  N   . TYR   B 1 242 ? -5.468  -7.534  25.141  1.00 32.16  ? 228 TYR   F N   1 
ATOM   4007 C  CA  . TYR   B 1 242 ? -6.654  -7.612  24.253  1.00 35.94  ? 228 TYR   F CA  1 
ATOM   4008 C  C   . TYR   B 1 242 ? -6.999  -6.255  23.632  1.00 36.45  ? 228 TYR   F C   1 
ATOM   4009 O  O   . TYR   B 1 242 ? -7.419  -6.249  22.463  1.00 36.80  ? 228 TYR   F O   1 
ATOM   4010 C  CB  . TYR   B 1 242 ? -7.851  -8.089  25.062  1.00 36.52  ? 228 TYR   F CB  1 
ATOM   4011 C  CG  . TYR   B 1 242 ? -9.035  -8.567  24.283  1.00 37.07  ? 228 TYR   F CG  1 
ATOM   4012 C  CD1 . TYR   B 1 242 ? -8.902  -9.511  23.278  1.00 41.06  ? 228 TYR   F CD1 1 
ATOM   4013 C  CD2 . TYR   B 1 242 ? -10.324 -8.140  24.603  1.00 38.92  ? 228 TYR   F CD2 1 
ATOM   4014 C  CE1 . TYR   B 1 242 ? -10.014 -10.013 22.614  1.00 38.95  ? 228 TYR   F CE1 1 
ATOM   4015 C  CE2 . TYR   B 1 242 ? -11.440 -8.631  23.948  1.00 39.25  ? 228 TYR   F CE2 1 
ATOM   4016 C  CZ  . TYR   B 1 242 ? -11.286 -9.581  22.955  1.00 41.38  ? 228 TYR   F CZ  1 
ATOM   4017 O  OH  . TYR   B 1 242 ? -12.385 -10.096 22.324  1.00 38.02  ? 228 TYR   F OH  1 
ATOM   4018 N  N   . GLY   B 1 243 ? -6.721  -5.142  24.314  1.00 38.47  ? 229 GLY   F N   1 
ATOM   4019 C  CA  . GLY   B 1 243 ? -7.067  -3.795  23.792  1.00 43.02  ? 229 GLY   F CA  1 
ATOM   4020 C  C   . GLY   B 1 243 ? -8.503  -3.750  23.254  1.00 41.43  ? 229 GLY   F C   1 
ATOM   4021 O  O   . GLY   B 1 243 ? -9.429  -4.230  23.918  1.00 45.87  ? 229 GLY   F O   1 
ATOM   4022 N  N   . PRO   B 1 244 ? -8.780  -3.239  22.032  1.00 43.19  ? 230 PRO   F N   1 
ATOM   4023 C  CA  . PRO   B 1 244 ? -7.750  -2.803  21.086  1.00 49.82  ? 230 PRO   F CA  1 
ATOM   4024 C  C   . PRO   B 1 244 ? -7.119  -1.469  21.466  1.00 50.83  ? 230 PRO   F C   1 
ATOM   4025 O  O   . PRO   B 1 244 ? -7.705  -0.698  22.211  1.00 53.35  ? 230 PRO   F O   1 
ATOM   4026 C  CB  . PRO   B 1 244 ? -8.484  -2.662  19.737  1.00 53.34  ? 230 PRO   F CB  1 
ATOM   4027 C  CG  . PRO   B 1 244 ? -9.963  -2.536  20.087  1.00 57.15  ? 230 PRO   F CG  1 
ATOM   4028 C  CD  . PRO   B 1 244 ? -10.143 -3.062  21.504  1.00 48.86  ? 230 PRO   F CD  1 
ATOM   4029 N  N   . PRO   B 1 245 ? -5.905  -1.163  20.981  1.00 47.55  ? 231 PRO   F N   1 
ATOM   4030 C  CA  . PRO   B 1 245 ? -5.180  -2.055  20.082  1.00 47.46  ? 231 PRO   F CA  1 
ATOM   4031 C  C   . PRO   B 1 245 ? -4.468  -3.174  20.861  1.00 44.00  ? 231 PRO   F C   1 
ATOM   4032 O  O   . PRO   B 1 245 ? -4.309  -3.078  22.063  1.00 39.78  ? 231 PRO   F O   1 
ATOM   4033 C  CB  . PRO   B 1 245 ? -4.198  -1.081  19.415  1.00 52.02  ? 231 PRO   F CB  1 
ATOM   4034 C  CG  . PRO   B 1 245 ? -3.846  -0.126  20.548  1.00 58.04  ? 231 PRO   F CG  1 
ATOM   4035 C  CD  . PRO   B 1 245 ? -5.144  0.049   21.318  1.00 55.83  ? 231 PRO   F CD  1 
ATOM   4036 N  N   . ILE   B 1 246 ? -4.032  -4.218  20.158  1.00 44.07  ? 232 ILE   F N   1 
ATOM   4037 C  CA  . ILE   B 1 246 ? -3.386  -5.401  20.791  1.00 39.19  ? 232 ILE   F CA  1 
ATOM   4038 C  C   . ILE   B 1 246 ? -2.030  -4.987  21.352  1.00 40.90  ? 232 ILE   F C   1 
ATOM   4039 O  O   . ILE   B 1 246 ? -1.298  -4.320  20.668  1.00 46.60  ? 232 ILE   F O   1 
ATOM   4040 C  CB  . ILE   B 1 246 ? -3.249  -6.548  19.786  1.00 39.93  ? 232 ILE   F CB  1 
ATOM   4041 C  CG1 . ILE   B 1 246 ? -4.623  -7.015  19.299  1.00 38.29  ? 232 ILE   F CG1 1 
ATOM   4042 C  CG2 . ILE   B 1 246 ? -2.416  -7.676  20.401  1.00 41.59  ? 232 ILE   F CG2 1 
ATOM   4043 C  CD1 . ILE   B 1 246 ? -4.563  -7.825  18.041  1.00 45.49  ? 232 ILE   F CD1 1 
ATOM   4044 N  N   . LYS   B 1 247 ? -1.705  -5.411  22.560  1.00 41.53  ? 233 LYS   F N   1 
ATOM   4045 C  CA  . LYS   B 1 247 ? -0.343  -5.287  23.115  1.00 42.21  ? 233 LYS   F CA  1 
ATOM   4046 C  C   . LYS   B 1 247 ? 0.242   -6.688  23.275  1.00 40.40  ? 233 LYS   F C   1 
ATOM   4047 O  O   . LYS   B 1 247 ? -0.093  -7.419  24.219  1.00 41.08  ? 233 LYS   F O   1 
ATOM   4048 C  CB  . LYS   B 1 247 ? -0.427  -4.502  24.422  1.00 43.86  ? 233 LYS   F CB  1 
ATOM   4049 C  CG  . LYS   B 1 247 ? -0.989  -3.095  24.280  1.00 47.44  ? 233 LYS   F CG  1 
ATOM   4050 C  CD  . LYS   B 1 247 ? -0.255  -2.138  25.219  1.00 60.78  ? 233 LYS   F CD  1 
ATOM   4051 C  CE  . LYS   B 1 247 ? -1.031  -0.904  25.601  1.00 67.38  ? 233 LYS   F CE  1 
ATOM   4052 N  NZ  . LYS   B 1 247 ? -0.610  -0.461  26.953  1.00 70.06  ? 233 LYS   F NZ  1 
ATOM   4053 N  N   . PRO   B 1 248 ? 1.130   -7.114  22.357  1.00 36.57  ? 234 PRO   F N   1 
ATOM   4054 C  CA  . PRO   B 1 248 ? 1.649   -8.471  22.425  1.00 39.53  ? 234 PRO   F CA  1 
ATOM   4055 C  C   . PRO   B 1 248 ? 2.638   -8.690  23.553  1.00 37.92  ? 234 PRO   F C   1 
ATOM   4056 O  O   . PRO   B 1 248 ? 3.210   -7.742  24.094  1.00 40.23  ? 234 PRO   F O   1 
ATOM   4057 C  CB  . PRO   B 1 248 ? 2.362   -8.640  21.075  1.00 40.41  ? 234 PRO   F CB  1 
ATOM   4058 C  CG  . PRO   B 1 248 ? 2.796   -7.227  20.725  1.00 45.18  ? 234 PRO   F CG  1 
ATOM   4059 C  CD  . PRO   B 1 248 ? 1.654   -6.352  21.202  1.00 39.61  ? 234 PRO   F CD  1 
ATOM   4060 N  N   . PRO   B 1 249 ? 2.849   -9.956  23.937  1.00 37.94  ? 235 PRO   F N   1 
ATOM   4061 C  CA  . PRO   B 1 249 ? 3.846   -10.307 24.943  1.00 41.96  ? 235 PRO   F CA  1 
ATOM   4062 C  C   . PRO   B 1 249 ? 5.307   -10.147 24.475  1.00 47.42  ? 235 PRO   F C   1 
ATOM   4063 O  O   . PRO   B 1 249 ? 5.562   -10.028 23.265  1.00 43.55  ? 235 PRO   F O   1 
ATOM   4064 C  CB  . PRO   B 1 249 ? 3.489   -11.776 25.248  1.00 44.47  ? 235 PRO   F CB  1 
ATOM   4065 C  CG  . PRO   B 1 249 ? 2.871   -12.292 23.973  1.00 43.21  ? 235 PRO   F CG  1 
ATOM   4066 C  CD  . PRO   B 1 249 ? 2.068   -11.118 23.471  1.00 41.60  ? 235 PRO   F CD  1 
ATOM   4067 N  N   . GLY   B 1 250 ? 6.228   -10.107 25.445  1.00 41.97  ? 236 GLY   F N   1 
ATOM   4068 C  CA  . GLY   B 1 250 ? 7.646   -9.708  25.256  1.00 45.12  ? 236 GLY   F CA  1 
ATOM   4069 C  C   . GLY   B 1 250 ? 8.455   -10.776 24.549  1.00 49.68  ? 236 GLY   F C   1 
ATOM   4070 O  O   . GLY   B 1 250 ? 9.576   -10.480 24.041  1.00 51.14  ? 236 GLY   F O   1 
ATOM   4071 N  N   . ILE   B 1 251 ? 7.984   -12.012 24.613  1.00 48.02  ? 237 ILE   F N   1 
ATOM   4072 C  CA  . ILE   B 1 251 ? 8.542   -13.090 23.767  1.00 55.30  ? 237 ILE   F CA  1 
ATOM   4073 C  C   . ILE   B 1 251 ? 7.345   -13.843 23.174  1.00 62.91  ? 237 ILE   F C   1 
ATOM   4074 O  O   . ILE   B 1 251 ? 6.252   -13.933 23.802  1.00 57.70  ? 237 ILE   F O   1 
ATOM   4075 C  CB  . ILE   B 1 251 ? 9.521   -13.966 24.579  1.00 60.23  ? 237 ILE   F CB  1 
ATOM   4076 C  CG1 . ILE   B 1 251 ? 10.580  -14.656 23.700  1.00 65.80  ? 237 ILE   F CG1 1 
ATOM   4077 C  CG2 . ILE   B 1 251 ? 8.734   -14.933 25.477  1.00 60.87  ? 237 ILE   F CG2 1 
ATOM   4078 C  CD1 . ILE   B 1 251 ? 10.327  -16.138 23.417  1.00 73.43  ? 237 ILE   F CD1 1 
ATOM   4079 N  N   . ILE   B 1 252 ? 7.544   -14.388 21.987  1.00 57.88  ? 238 ILE   F N   1 
ATOM   4080 C  CA  . ILE   B 1 252 ? 6.421   -14.970 21.223  1.00 55.25  ? 238 ILE   F CA  1 
ATOM   4081 C  C   . ILE   B 1 252 ? 7.025   -16.019 20.304  1.00 48.75  ? 238 ILE   F C   1 
ATOM   4082 O  O   . ILE   B 1 252 ? 8.108   -15.768 19.802  1.00 54.17  ? 238 ILE   F O   1 
ATOM   4083 C  CB  . ILE   B 1 252 ? 5.795   -13.772 20.501  1.00 52.30  ? 238 ILE   F CB  1 
ATOM   4084 C  CG1 . ILE   B 1 252 ? 4.321   -13.960 20.178  1.00 52.26  ? 238 ILE   F CG1 1 
ATOM   4085 C  CG2 . ILE   B 1 252 ? 6.620   -13.390 19.287  1.00 58.38  ? 238 ILE   F CG2 1 
ATOM   4086 C  CD1 . ILE   B 1 252 ? 3.636   -12.620 20.030  1.00 63.29  ? 238 ILE   F CD1 1 
ATOM   4087 N  N   . TYR   B 1 253 ? 6.359   -17.135 20.067  1.00 37.31  ? 239 TYR   F N   1 
ATOM   4088 C  CA  . TYR   B 1 253 ? 6.860   -18.078 19.052  1.00 37.85  ? 239 TYR   F CA  1 
ATOM   4089 C  C   . TYR   B 1 253 ? 6.544   -17.521 17.647  1.00 36.96  ? 239 TYR   F C   1 
ATOM   4090 O  O   . TYR   B 1 253 ? 7.468   -17.406 16.820  1.00 37.59  ? 239 TYR   F O   1 
ATOM   4091 C  CB  . TYR   B 1 253 ? 6.273   -19.478 19.227  1.00 35.06  ? 239 TYR   F CB  1 
ATOM   4092 C  CG  . TYR   B 1 253 ? 6.642   -20.351 18.075  1.00 33.11  ? 239 TYR   F CG  1 
ATOM   4093 C  CD1 . TYR   B 1 253 ? 7.977   -20.659 17.796  1.00 38.31  ? 239 TYR   F CD1 1 
ATOM   4094 C  CD2 . TYR   B 1 253 ? 5.660   -20.857 17.241  1.00 33.84  ? 239 TYR   F CD2 1 
ATOM   4095 C  CE1 . TYR   B 1 253 ? 8.322   -21.472 16.716  1.00 35.18  ? 239 TYR   F CE1 1 
ATOM   4096 C  CE2 . TYR   B 1 253 ? 5.997   -21.663 16.170  1.00 34.70  ? 239 TYR   F CE2 1 
ATOM   4097 C  CZ  . TYR   B 1 253 ? 7.320   -21.966 15.904  1.00 33.99  ? 239 TYR   F CZ  1 
ATOM   4098 O  OH  . TYR   B 1 253 ? 7.576   -22.747 14.814  1.00 39.25  ? 239 TYR   F OH  1 
ATOM   4099 N  N   . ASP   B 1 254 ? 5.268   -17.223 17.361  1.00 33.56  ? 240 ASP   F N   1 
ATOM   4100 C  CA  . ASP   B 1 254 ? 4.778   -16.829 16.015  1.00 33.34  ? 240 ASP   F CA  1 
ATOM   4101 C  C   . ASP   B 1 254 ? 4.002   -15.513 16.121  1.00 35.99  ? 240 ASP   F C   1 
ATOM   4102 O  O   . ASP   B 1 254 ? 2.848   -15.555 16.506  1.00 34.09  ? 240 ASP   F O   1 
ATOM   4103 C  CB  . ASP   B 1 254 ? 3.899   -17.956 15.466  1.00 34.44  ? 240 ASP   F CB  1 
ATOM   4104 C  CG  . ASP   B 1 254 ? 3.226   -17.635 14.146  1.00 35.27  ? 240 ASP   F CG  1 
ATOM   4105 O  OD1 . ASP   B 1 254 ? 3.578   -16.604 13.539  1.00 34.85  ? 240 ASP   F OD1 1 
ATOM   4106 O  OD2 . ASP   B 1 254 ? 2.313   -18.410 13.759  1.00 34.55  ? 240 ASP   F OD2 1 
ATOM   4107 N  N   . SER   B 1 255 ? 4.632   -14.370 15.920  1.00 35.31  ? 241 SER   F N   1 
ATOM   4108 C  CA  . SER   B 1 255 ? 4.007   -13.048 16.198  1.00 35.52  ? 241 SER   F CA  1 
ATOM   4109 C  C   . SER   B 1 255 ? 2.777   -12.887 15.304  1.00 33.13  ? 241 SER   F C   1 
ATOM   4110 O  O   . SER   B 1 255 ? 1.758   -12.403 15.787  1.00 35.80  ? 241 SER   F O   1 
ATOM   4111 C  CB  . SER   B 1 255 ? 4.972   -11.913 16.001  1.00 36.85  ? 241 SER   F CB  1 
ATOM   4112 O  OG  . SER   B 1 255 ? 5.580   -11.992 14.715  1.00 34.51  ? 241 SER   F OG  1 
ATOM   4113 N  N   . LEU   B 1 256 ? 2.852   -13.303 14.039  1.00 32.85  ? 242 LEU   F N   1 
ATOM   4114 C  CA  . LEU   B 1 256 ? 1.743   -13.141 13.064  1.00 34.45  ? 242 LEU   F CA  1 
ATOM   4115 C  C   . LEU   B 1 256 ? 0.568   -13.992 13.548  1.00 35.62  ? 242 LEU   F C   1 
ATOM   4116 O  O   . LEU   B 1 256 ? -0.550  -13.486 13.553  1.00 32.38  ? 242 LEU   F O   1 
ATOM   4117 C  CB  . LEU   B 1 256 ? 2.171   -13.554 11.652  1.00 34.86  ? 242 LEU   F CB  1 
ATOM   4118 C  CG  . LEU   B 1 256 ? 3.180   -12.628 10.959  1.00 39.12  ? 242 LEU   F CG  1 
ATOM   4119 C  CD1 . LEU   B 1 256 ? 3.417   -13.079 9.516   1.00 39.32  ? 242 LEU   F CD1 1 
ATOM   4120 C  CD2 . LEU   B 1 256 ? 2.717   -11.175 10.955  1.00 41.77  ? 242 LEU   F CD2 1 
ATOM   4121 N  N   . GLY   B 1 257 ? 0.818   -15.261 13.896  1.00 31.25  ? 243 GLY   F N   1 
ATOM   4122 C  CA  . GLY   B 1 257 ? -0.240  -16.167 14.361  1.00 32.69  ? 243 GLY   F CA  1 
ATOM   4123 C  C   . GLY   B 1 257 ? -0.863  -15.627 15.655  1.00 31.22  ? 243 GLY   F C   1 
ATOM   4124 O  O   . GLY   B 1 257 ? -2.093  -15.709 15.816  1.00 31.73  ? 243 GLY   F O   1 
ATOM   4125 N  N   . TYR   B 1 258 ? -0.042  -15.076 16.542  1.00 32.11  ? 244 TYR   F N   1 
ATOM   4126 C  CA  . TYR   B 1 258 ? -0.515  -14.477 17.810  1.00 33.58  ? 244 TYR   F CA  1 
ATOM   4127 C  C   . TYR   B 1 258 ? -1.540  -13.375 17.476  1.00 35.28  ? 244 TYR   F C   1 
ATOM   4128 O  O   . TYR   B 1 258 ? -2.672  -13.370 17.963  1.00 33.72  ? 244 TYR   F O   1 
ATOM   4129 C  CB  . TYR   B 1 258 ? 0.646   -13.929 18.645  1.00 31.79  ? 244 TYR   F CB  1 
ATOM   4130 C  CG  . TYR   B 1 258 ? 0.184   -13.121 19.834  1.00 34.12  ? 244 TYR   F CG  1 
ATOM   4131 C  CD1 . TYR   B 1 258 ? -0.105  -13.755 21.036  1.00 35.37  ? 244 TYR   F CD1 1 
ATOM   4132 C  CD2 . TYR   B 1 258 ? -0.100  -11.771 19.728  1.00 35.84  ? 244 TYR   F CD2 1 
ATOM   4133 C  CE1 . TYR   B 1 258 ? -0.624  -13.064 22.116  1.00 34.88  ? 244 TYR   F CE1 1 
ATOM   4134 C  CE2 . TYR   B 1 258 ? -0.603  -11.060 20.811  1.00 35.36  ? 244 TYR   F CE2 1 
ATOM   4135 C  CZ  . TYR   B 1 258 ? -0.899  -11.719 21.993  1.00 35.90  ? 244 TYR   F CZ  1 
ATOM   4136 O  OH  . TYR   B 1 258 ? -1.404  -11.064 23.062  1.00 35.37  ? 244 TYR   F OH  1 
ATOM   4137 N  N   . MET   B 1 259 ? -1.139  -12.419 16.648  1.00 33.56  ? 245 MET   F N   1 
ATOM   4138 C  CA  . MET   B 1 259 ? -2.004  -11.246 16.319  1.00 33.75  ? 245 MET   F CA  1 
ATOM   4139 C  C   . MET   B 1 259 ? -3.272  -11.750 15.622  1.00 35.91  ? 245 MET   F C   1 
ATOM   4140 O  O   . MET   B 1 259 ? -4.344  -11.250 15.966  1.00 37.15  ? 245 MET   F O   1 
ATOM   4141 C  CB  . MET   B 1 259 ? -1.279  -10.263 15.394  1.00 36.80  ? 245 MET   F CB  1 
ATOM   4142 C  CG  . MET   B 1 259 ? -0.041  -9.665  15.983  1.00 38.54  ? 245 MET   F CG  1 
ATOM   4143 S  SD  . MET   B 1 259 ? -0.369  -8.685  17.467  1.00 43.66  ? 245 MET   F SD  1 
ATOM   4144 C  CE  . MET   B 1 259 ? -1.168  -7.285  16.668  1.00 51.77  ? 245 MET   F CE  1 
ATOM   4145 N  N   . ASN   B 1 260 ? -3.168  -12.662 14.642  1.00 32.46  ? 246 ASN   F N   1 
ATOM   4146 C  CA  . ASN   B 1 260 ? -4.347  -13.239 13.963  1.00 34.68  ? 246 ASN   F CA  1 
ATOM   4147 C  C   . ASN   B 1 260 ? -5.268  -13.926 14.996  1.00 35.92  ? 246 ASN   F C   1 
ATOM   4148 O  O   . ASN   B 1 260 ? -6.494  -13.773 14.862  1.00 33.86  ? 246 ASN   F O   1 
ATOM   4149 C  CB  . ASN   B 1 260 ? -4.038  -14.237 12.853  1.00 37.73  ? 246 ASN   F CB  1 
ATOM   4150 C  CG  . ASN   B 1 260 ? -3.288  -13.601 11.693  1.00 45.94  ? 246 ASN   F CG  1 
ATOM   4151 O  OD1 . ASN   B 1 260 ? -3.360  -12.401 11.469  1.00 40.97  ? 246 ASN   F OD1 1 
ATOM   4152 N  ND2 . ASN   B 1 260 ? -2.493  -14.393 11.009  1.00 47.82  ? 246 ASN   F ND2 1 
ATOM   4153 N  N   . THR   B 1 261 ? -4.704  -14.646 15.958  1.00 32.67  ? 247 THR   F N   1 
ATOM   4154 C  CA  . THR   B 1 261 ? -5.488  -15.400 16.970  1.00 33.92  ? 247 THR   F CA  1 
ATOM   4155 C  C   . THR   B 1 261 ? -6.286  -14.395 17.812  1.00 34.29  ? 247 THR   F C   1 
ATOM   4156 O  O   . THR   B 1 261 ? -7.499  -14.642 18.045  1.00 32.89  ? 247 THR   F O   1 
ATOM   4157 C  CB  . THR   B 1 261 ? -4.617  -16.358 17.787  1.00 32.61  ? 247 THR   F CB  1 
ATOM   4158 O  OG1 . THR   B 1 261 ? -4.130  -17.388 16.928  1.00 32.02  ? 247 THR   F OG1 1 
ATOM   4159 C  CG2 . THR   B 1 261 ? -5.388  -17.023 18.909  1.00 33.18  ? 247 THR   F CG2 1 
ATOM   4160 N  N   . VAL   B 1 262 ? -5.688  -13.299 18.254  1.00 32.12  ? 248 VAL   F N   1 
ATOM   4161 C  CA  . VAL   B 1 262 ? -6.448  -12.355 19.134  1.00 32.03  ? 248 VAL   F CA  1 
ATOM   4162 C  C   . VAL   B 1 262 ? -7.650  -11.798 18.374  1.00 32.75  ? 248 VAL   F C   1 
ATOM   4163 O  O   . VAL   B 1 262 ? -8.764  -11.751 18.944  1.00 31.82  ? 248 VAL   F O   1 
ATOM   4164 C  CB  . VAL   B 1 262 ? -5.548  -11.247 19.680  1.00 31.55  ? 248 VAL   F CB  1 
ATOM   4165 C  CG1 . VAL   B 1 262 ? -6.373  -10.258 20.512  1.00 33.68  ? 248 VAL   F CG1 1 
ATOM   4166 C  CG2 . VAL   B 1 262 ? -4.368  -11.798 20.468  1.00 33.95  ? 248 VAL   F CG2 1 
ATOM   4167 N  N   . GLU   B 1 263 ? -7.456  -11.404 17.113  1.00 34.06  ? 249 GLU   F N   1 
ATOM   4168 C  CA  . GLU   B 1 263 ? -8.539  -10.819 16.282  1.00 38.07  ? 249 GLU   F CA  1 
ATOM   4169 C  C   . GLU   B 1 263 ? -9.572  -11.900 15.978  1.00 35.18  ? 249 GLU   F C   1 
ATOM   4170 O  O   . GLU   B 1 263 ? -10.745 -11.593 15.929  1.00 35.40  ? 249 GLU   F O   1 
ATOM   4171 C  CB  . GLU   B 1 263 ? -7.968  -10.152 15.019  1.00 40.85  ? 249 GLU   F CB  1 
ATOM   4172 C  CG  . GLU   B 1 263 ? -7.264  -8.830  15.324  1.00 46.21  ? 249 GLU   F CG  1 
ATOM   4173 C  CD  . GLU   B 1 263 ? -8.094  -7.822  16.148  1.00 52.43  ? 249 GLU   F CD  1 
ATOM   4174 O  OE1 . GLU   B 1 263 ? -9.370  -7.809  16.052  1.00 48.63  ? 249 GLU   F OE1 1 
ATOM   4175 O  OE2 . GLU   B 1 263 ? -7.482  -7.022  16.871  1.00 54.91  ? 249 GLU   F OE2 1 
ATOM   4176 N  N   . ARG   B 1 264 ? -9.173  -13.159 15.829  1.00 36.58  ? 250 ARG   F N   1 
ATOM   4177 C  CA  . ARG   B 1 264 ? -10.150 -14.247 15.561  1.00 34.15  ? 250 ARG   F CA  1 
ATOM   4178 C  C   . ARG   B 1 264 ? -11.040 -14.429 16.801  1.00 33.35  ? 250 ARG   F C   1 
ATOM   4179 O  O   . ARG   B 1 264 ? -12.240 -14.539 16.665  1.00 32.37  ? 250 ARG   F O   1 
ATOM   4180 C  CB  . ARG   B 1 264 ? -9.433  -15.551 15.231  1.00 38.48  ? 250 ARG   F CB  1 
ATOM   4181 C  CG  . ARG   B 1 264 ? -10.335 -16.775 15.162  1.00 37.54  ? 250 ARG   F CG  1 
ATOM   4182 C  CD  . ARG   B 1 264 ? -9.513  -17.995 14.849  1.00 40.91  ? 250 ARG   F CD  1 
ATOM   4183 N  NE  . ARG   B 1 264 ? -10.345 -19.177 14.932  1.00 40.06  ? 250 ARG   F NE  1 
ATOM   4184 C  CZ  . ARG   B 1 264 ? -9.908  -20.417 15.045  1.00 41.18  ? 250 ARG   F CZ  1 
ATOM   4185 N  NH1 . ARG   B 1 264 ? -8.617  -20.678 15.071  1.00 41.52  ? 250 ARG   F NH1 1 
ATOM   4186 N  NH2 . ARG   B 1 264 ? -10.780 -21.395 15.100  1.00 43.66  ? 250 ARG   F NH2 1 
ATOM   4187 N  N   . ILE   B 1 265 ? -10.426 -14.444 17.971  1.00 30.13  ? 251 ILE   F N   1 
ATOM   4188 C  CA  . ILE   B 1 265 ? -11.149 -14.524 19.263  1.00 33.52  ? 251 ILE   F CA  1 
ATOM   4189 C  C   . ILE   B 1 265 ? -12.103 -13.312 19.394  1.00 31.32  ? 251 ILE   F C   1 
ATOM   4190 O  O   . ILE   B 1 265 ? -13.250 -13.536 19.772  1.00 34.39  ? 251 ILE   F O   1 
ATOM   4191 C  CB  . ILE   B 1 265 ? -10.181 -14.650 20.447  1.00 33.44  ? 251 ILE   F CB  1 
ATOM   4192 C  CG1 . ILE   B 1 265 ? -9.411  -15.980 20.411  1.00 32.87  ? 251 ILE   F CG1 1 
ATOM   4193 C  CG2 . ILE   B 1 265 ? -10.931 -14.444 21.765  1.00 36.78  ? 251 ILE   F CG2 1 
ATOM   4194 C  CD1 . ILE   B 1 265 ? -8.271  -16.054 21.364  1.00 33.64  ? 251 ILE   F CD1 1 
ATOM   4195 N  N   . ARG   B 1 266 ? -11.639 -12.092 19.128  1.00 36.02  ? 252 ARG   F N   1 
ATOM   4196 C  CA  . ARG   B 1 266 ? -12.501 -10.881 19.145  1.00 35.69  ? 252 ARG   F CA  1 
ATOM   4197 C  C   . ARG   B 1 266 ? -13.734 -11.081 18.252  1.00 41.08  ? 252 ARG   F C   1 
ATOM   4198 O  O   . ARG   B 1 266 ? -14.844 -10.715 18.705  1.00 36.18  ? 252 ARG   F O   1 
ATOM   4199 C  CB  . ARG   B 1 266 ? -11.712 -9.636  18.756  1.00 39.03  ? 252 ARG   F CB  1 
ATOM   4200 C  CG  . ARG   B 1 266 ? -12.408 -8.364  19.225  1.00 45.86  ? 252 ARG   F CG  1 
ATOM   4201 C  CD  . ARG   B 1 266 ? -11.795 -7.112  18.646  1.00 43.13  ? 252 ARG   F CD  1 
ATOM   4202 N  NE  . ARG   B 1 266 ? -10.336 -7.126  18.729  1.00 39.82  ? 252 ARG   F NE  1 
ATOM   4203 C  CZ  . ARG   B 1 266 ? -9.623  -6.924  19.822  1.00 39.44  ? 252 ARG   F CZ  1 
ATOM   4204 N  NH1 . ARG   B 1 266 ? -10.222 -6.724  20.988  1.00 38.86  ? 252 ARG   F NH1 1 
ATOM   4205 N  NH2 . ARG   B 1 266 ? -8.302  -6.919  19.735  1.00 42.28  ? 252 ARG   F NH2 1 
ATOM   4206 N  N   . ARG   B 1 267 ? -13.571 -11.632 17.043  1.00 36.52  ? 253 ARG   F N   1 
ATOM   4207 C  CA  . ARG   B 1 267 ? -14.675 -11.818 16.070  1.00 40.90  ? 253 ARG   F CA  1 
ATOM   4208 C  C   . ARG   B 1 267 ? -15.641 -12.916 16.591  1.00 41.78  ? 253 ARG   F C   1 
ATOM   4209 O  O   . ARG   B 1 267 ? -16.872 -12.737 16.527  1.00 37.09  ? 253 ARG   F O   1 
ATOM   4210 C  CB  . ARG   B 1 267 ? -14.129 -12.107 14.664  1.00 43.23  ? 253 ARG   F CB  1 
ATOM   4211 C  CG  . ARG   B 1 267 ? -15.140 -12.781 13.745  1.00 57.46  ? 253 ARG   F CG  1 
ATOM   4212 C  CD  . ARG   B 1 267 ? -14.654 -13.514 12.499  1.00 69.97  ? 253 ARG   F CD  1 
ATOM   4213 N  NE  . ARG   B 1 267 ? -13.757 -14.671 12.673  1.00 73.98  ? 253 ARG   F NE  1 
ATOM   4214 C  CZ  . ARG   B 1 267 ? -14.115 -15.919 13.006  1.00 66.20  ? 253 ARG   F CZ  1 
ATOM   4215 N  NH1 . ARG   B 1 267 ? -15.372 -16.220 13.279  1.00 62.12  ? 253 ARG   F NH1 1 
ATOM   4216 N  NH2 . ARG   B 1 267 ? -13.191 -16.861 13.091  1.00 68.97  ? 253 ARG   F NH2 1 
ATOM   4217 N  N   . ILE   B 1 268 ? -15.123 -14.050 17.046  1.00 36.65  ? 254 ILE   F N   1 
ATOM   4218 C  CA  . ILE   B 1 268 ? -15.965 -15.146 17.605  1.00 38.52  ? 254 ILE   F CA  1 
ATOM   4219 C  C   . ILE   B 1 268 ? -16.776 -14.588 18.780  1.00 37.05  ? 254 ILE   F C   1 
ATOM   4220 O  O   . ILE   B 1 268 ? -17.949 -14.896 18.836  1.00 38.61  ? 254 ILE   F O   1 
ATOM   4221 C  CB  . ILE   B 1 268 ? -15.128 -16.360 18.044  1.00 38.57  ? 254 ILE   F CB  1 
ATOM   4222 C  CG1 . ILE   B 1 268 ? -14.386 -17.007 16.862  1.00 41.58  ? 254 ILE   F CG1 1 
ATOM   4223 C  CG2 . ILE   B 1 268 ? -16.020 -17.358 18.765  1.00 37.75  ? 254 ILE   F CG2 1 
ATOM   4224 C  CD1 . ILE   B 1 268 ? -13.345 -18.015 17.291  1.00 40.76  ? 254 ILE   F CD1 1 
ATOM   4225 N  N   . ALA   B 1 269 ? -16.185 -13.796 19.673  1.00 35.72  ? 255 ALA   F N   1 
ATOM   4226 C  CA  . ALA   B 1 269 ? -16.900 -13.251 20.840  1.00 37.50  ? 255 ALA   F CA  1 
ATOM   4227 C  C   . ALA   B 1 269 ? -18.078 -12.367 20.369  1.00 39.88  ? 255 ALA   F C   1 
ATOM   4228 O  O   . ALA   B 1 269 ? -19.167 -12.447 20.972  1.00 36.07  ? 255 ALA   F O   1 
ATOM   4229 C  CB  . ALA   B 1 269 ? -15.940 -12.473 21.711  1.00 36.16  ? 255 ALA   F CB  1 
ATOM   4230 N  N   . GLN   B 1 270 ? -17.837 -11.506 19.381  1.00 39.54  ? 256 GLN   F N   1 
ATOM   4231 C  CA  . GLN   B 1 270 ? -18.835 -10.596 18.742  1.00 39.19  ? 256 GLN   F CA  1 
ATOM   4232 C  C   . GLN   B 1 270 ? -19.964 -11.414 18.108  1.00 39.83  ? 256 GLN   F C   1 
ATOM   4233 O  O   . GLN   B 1 270 ? -21.142 -11.196 18.451  1.00 40.75  ? 256 GLN   F O   1 
ATOM   4234 C  CB  . GLN   B 1 270 ? -18.130 -9.681  17.740  1.00 45.03  ? 256 GLN   F CB  1 
ATOM   4235 C  CG  . GLN   B 1 270 ? -19.027 -8.572  17.181  1.00 51.98  ? 256 GLN   F CG  1 
ATOM   4236 C  CD  . GLN   B 1 270 ? -18.913 -8.438  15.677  1.00 62.97  ? 256 GLN   F CD  1 
ATOM   4237 O  OE1 . GLN   B 1 270 ? -17.945 -8.880  15.047  1.00 62.23  ? 256 GLN   F OE1 1 
ATOM   4238 N  NE2 . GLN   B 1 270 ? -19.937 -7.856  15.076  1.00 59.48  ? 256 GLN   F NE2 1 
ATOM   4239 N  N   . GLU   B 1 271 ? -19.636 -12.382 17.275  1.00 37.61  ? 257 GLU   F N   1 
ATOM   4240 C  CA  . GLU   B 1 271 ? -20.618 -13.129 16.456  1.00 44.03  ? 257 GLU   F CA  1 
ATOM   4241 C  C   . GLU   B 1 271 ? -21.423 -14.078 17.356  1.00 46.77  ? 257 GLU   F C   1 
ATOM   4242 O  O   . GLU   B 1 271 ? -22.577 -14.324 17.017  1.00 45.12  ? 257 GLU   F O   1 
ATOM   4243 C  CB  . GLU   B 1 271 ? -19.910 -13.882 15.314  1.00 46.68  ? 257 GLU   F CB  1 
ATOM   4244 C  CG  . GLU   B 1 271 ? -19.393 -12.968 14.202  1.00 47.95  ? 257 GLU   F CG  1 
ATOM   4245 C  CD  . GLU   B 1 271 ? -18.576 -13.631 13.094  1.00 52.14  ? 257 GLU   F CD  1 
ATOM   4246 O  OE1 . GLU   B 1 271 ? -18.495 -14.887 13.054  1.00 54.03  ? 257 GLU   F OE1 1 
ATOM   4247 O  OE2 . GLU   B 1 271 ? -17.949 -12.881 12.314  1.00 55.31  ? 257 GLU   F OE2 1 
ATOM   4248 N  N   . THR   B 1 272 ? -20.881 -14.575 18.479  1.00 43.31  ? 258 THR   F N   1 
ATOM   4249 C  CA  . THR   B 1 272 ? -21.583 -15.563 19.332  1.00 43.92  ? 258 THR   F CA  1 
ATOM   4250 C  C   . THR   B 1 272 ? -22.028 -14.942 20.661  1.00 43.73  ? 258 THR   F C   1 
ATOM   4251 O  O   . THR   B 1 272 ? -22.617 -15.670 21.442  1.00 41.45  ? 258 THR   F O   1 
ATOM   4252 C  CB  . THR   B 1 272 ? -20.722 -16.816 19.552  1.00 47.72  ? 258 THR   F CB  1 
ATOM   4253 O  OG1 . THR   B 1 272 ? -19.671 -16.373 20.412  1.00 37.58  ? 258 THR   F OG1 1 
ATOM   4254 C  CG2 . THR   B 1 272 ? -20.216 -17.430 18.255  1.00 41.24  ? 258 THR   F CG2 1 
ATOM   4255 N  N   . LYS   B 1 273 ? -21.768 -13.654 20.897  1.00 40.78  ? 259 LYS   F N   1 
ATOM   4256 C  CA  . LYS   B 1 273 ? -22.034 -12.925 22.179  1.00 42.93  ? 259 LYS   F CA  1 
ATOM   4257 C  C   . LYS   B 1 273 ? -21.428 -13.695 23.364  1.00 42.03  ? 259 LYS   F C   1 
ATOM   4258 O  O   . LYS   B 1 273 ? -22.141 -13.972 24.348  1.00 44.81  ? 259 LYS   F O   1 
ATOM   4259 C  CB  . LYS   B 1 273 ? -23.539 -12.658 22.321  1.00 53.04  ? 259 LYS   F CB  1 
ATOM   4260 C  CG  . LYS   B 1 273 ? -24.242 -12.231 21.027  1.00 68.28  ? 259 LYS   F CG  1 
ATOM   4261 C  CD  . LYS   B 1 273 ? -25.743 -12.529 21.024  1.00 84.97  ? 259 LYS   F CD  1 
ATOM   4262 C  CE  . LYS   B 1 273 ? -26.366 -12.641 19.643  1.00 97.87  ? 259 LYS   F CE  1 
ATOM   4263 N  NZ  . LYS   B 1 273 ? -26.511 -11.314 18.994  1.00 103.79 ? 259 LYS   F NZ  1 
ATOM   4264 N  N   . SER   B 1 274 ? -20.134 -14.019 23.293  1.00 37.07  ? 260 SER   F N   1 
ATOM   4265 C  CA  . SER   B 1 274 ? -19.437 -14.826 24.324  1.00 36.56  ? 260 SER   F CA  1 
ATOM   4266 C  C   . SER   B 1 274 ? -18.564 -13.879 25.140  1.00 37.13  ? 260 SER   F C   1 
ATOM   4267 O  O   . SER   B 1 274 ? -17.990 -12.978 24.565  1.00 37.82  ? 260 SER   F O   1 
ATOM   4268 C  CB  . SER   B 1 274 ? -18.634 -15.959 23.747  1.00 38.28  ? 260 SER   F CB  1 
ATOM   4269 O  OG  . SER   B 1 274 ? -19.457 -16.856 22.998  1.00 38.41  ? 260 SER   F OG  1 
ATOM   4270 N  N   . GLN   B 1 275 ? -18.389 -14.181 26.414  1.00 34.96  ? 261 GLN   F N   1 
ATOM   4271 C  CA  . GLN   B 1 275 ? -17.326 -13.585 27.255  1.00 38.09  ? 261 GLN   F CA  1 
ATOM   4272 C  C   . GLN   B 1 275 ? -15.982 -14.198 26.847  1.00 36.26  ? 261 GLN   F C   1 
ATOM   4273 O  O   . GLN   B 1 275 ? -15.965 -15.375 26.385  1.00 37.53  ? 261 GLN   F O   1 
ATOM   4274 C  CB  . GLN   B 1 275 ? -17.538 -13.937 28.726  1.00 36.53  ? 261 GLN   F CB  1 
ATOM   4275 C  CG  . GLN   B 1 275 ? -18.842 -13.440 29.319  1.00 42.58  ? 261 GLN   F CG  1 
ATOM   4276 C  CD  . GLN   B 1 275 ? -18.972 -14.003 30.722  1.00 47.30  ? 261 GLN   F CD  1 
ATOM   4277 O  OE1 . GLN   B 1 275 ? -18.066 -13.852 31.544  1.00 39.59  ? 261 GLN   F OE1 1 
ATOM   4278 N  NE2 . GLN   B 1 275 ? -20.065 -14.687 30.997  1.00 46.43  ? 261 GLN   F NE2 1 
ATOM   4279 N  N   . VAL   B 1 276 ? -14.910 -13.431 26.980  1.00 35.40  ? 262 VAL   F N   1 
ATOM   4280 C  CA  . VAL   B 1 276 ? -13.547 -13.946 26.754  1.00 38.16  ? 262 VAL   F CA  1 
ATOM   4281 C  C   . VAL   B 1 276 ? -12.862 -14.017 28.124  1.00 37.82  ? 262 VAL   F C   1 
ATOM   4282 O  O   . VAL   B 1 276 ? -12.657 -12.991 28.739  1.00 36.57  ? 262 VAL   F O   1 
ATOM   4283 C  CB  . VAL   B 1 276 ? -12.808 -13.089 25.721  1.00 38.24  ? 262 VAL   F CB  1 
ATOM   4284 C  CG1 . VAL   B 1 276 ? -11.395 -13.585 25.532  1.00 38.81  ? 262 VAL   F CG1 1 
ATOM   4285 C  CG2 . VAL   B 1 276 ? -13.548 -13.055 24.375  1.00 38.55  ? 262 VAL   F CG2 1 
ATOM   4286 N  N   . TRP   B 1 277 ? -12.456 -15.205 28.536  1.00 35.47  ? 263 TRP   F N   1 
ATOM   4287 C  CA  . TRP   B 1 277 ? -11.669 -15.416 29.776  1.00 34.92  ? 263 TRP   F CA  1 
ATOM   4288 C  C   . TRP   B 1 277 ? -10.172 -15.514 29.426  1.00 34.80  ? 263 TRP   F C   1 
ATOM   4289 O  O   . TRP   B 1 277 ? -9.769  -16.464 28.738  1.00 35.51  ? 263 TRP   F O   1 
ATOM   4290 C  CB  . TRP   B 1 277 ? -12.185 -16.643 30.507  1.00 33.67  ? 263 TRP   F CB  1 
ATOM   4291 C  CG  . TRP   B 1 277 ? -13.544 -16.446 31.094  1.00 36.71  ? 263 TRP   F CG  1 
ATOM   4292 C  CD1 . TRP   B 1 277 ? -14.385 -15.402 30.893  1.00 39.15  ? 263 TRP   F CD1 1 
ATOM   4293 C  CD2 . TRP   B 1 277 ? -14.239 -17.342 31.987  1.00 34.45  ? 263 TRP   F CD2 1 
ATOM   4294 N  NE1 . TRP   B 1 277 ? -15.558 -15.590 31.593  1.00 41.07  ? 263 TRP   F NE1 1 
ATOM   4295 C  CE2 . TRP   B 1 277 ? -15.495 -16.773 32.264  1.00 34.73  ? 263 TRP   F CE2 1 
ATOM   4296 C  CE3 . TRP   B 1 277 ? -13.911 -18.564 32.586  1.00 39.16  ? 263 TRP   F CE3 1 
ATOM   4297 C  CZ2 . TRP   B 1 277 ? -16.420 -17.371 33.125  1.00 39.06  ? 263 TRP   F CZ2 1 
ATOM   4298 C  CZ3 . TRP   B 1 277 ? -14.813 -19.144 33.448  1.00 37.14  ? 263 TRP   F CZ3 1 
ATOM   4299 C  CH2 . TRP   B 1 277 ? -16.037 -18.544 33.733  1.00 38.80  ? 263 TRP   F CH2 1 
ATOM   4300 N  N   . PHE   B 1 278 ? -9.414  -14.537 29.892  1.00 31.59  ? 264 PHE   F N   1 
ATOM   4301 C  CA  . PHE   B 1 278 ? -7.975  -14.326 29.618  1.00 33.38  ? 264 PHE   F CA  1 
ATOM   4302 C  C   . PHE   B 1 278 ? -7.210  -15.359 30.443  1.00 35.98  ? 264 PHE   F C   1 
ATOM   4303 O  O   . PHE   B 1 278 ? -7.749  -15.953 31.420  1.00 35.74  ? 264 PHE   F O   1 
ATOM   4304 C  CB  . PHE   B 1 278 ? -7.619  -12.862 29.885  1.00 33.36  ? 264 PHE   F CB  1 
ATOM   4305 C  CG  . PHE   B 1 278 ? -8.480  -11.843 29.161  1.00 35.12  ? 264 PHE   F CG  1 
ATOM   4306 C  CD1 . PHE   B 1 278 ? -8.667  -11.900 27.785  1.00 33.40  ? 264 PHE   F CD1 1 
ATOM   4307 C  CD2 . PHE   B 1 278 ? -9.128  -10.827 29.848  1.00 38.23  ? 264 PHE   F CD2 1 
ATOM   4308 C  CE1 . PHE   B 1 278 ? -9.400  -10.931 27.105  1.00 36.34  ? 264 PHE   F CE1 1 
ATOM   4309 C  CE2 . PHE   B 1 278 ? -9.919  -9.894  29.178  1.00 39.68  ? 264 PHE   F CE2 1 
ATOM   4310 C  CZ  . PHE   B 1 278 ? -10.033 -9.928  27.798  1.00 35.97  ? 264 PHE   F CZ  1 
ATOM   4311 N  N   . GLY   B 1 279 ? -5.984  -15.630 30.034  1.00 31.49  ? 265 GLY   F N   1 
ATOM   4312 C  CA  . GLY   B 1 279 ? -5.140  -16.589 30.758  1.00 34.92  ? 265 GLY   F CA  1 
ATOM   4313 C  C   . GLY   B 1 279 ? -4.761  -16.124 32.160  1.00 36.98  ? 265 GLY   F C   1 
ATOM   4314 O  O   . GLY   B 1 279 ? -4.729  -16.981 33.057  1.00 33.92  ? 265 GLY   F O   1 
ATOM   4315 N  N   . HIS   B 1 280 ? -4.422  -14.841 32.366  1.00 36.60  ? 266 HIS   F N   1 
ATOM   4316 C  CA  . HIS   B 1 280 ? -3.701  -14.414 33.602  1.00 36.64  ? 266 HIS   F CA  1 
ATOM   4317 C  C   . HIS   B 1 280 ? -4.059  -12.967 34.002  1.00 35.53  ? 266 HIS   F C   1 
ATOM   4318 O  O   . HIS   B 1 280 ? -3.144  -12.157 34.253  1.00 38.96  ? 266 HIS   F O   1 
ATOM   4319 C  CB  . HIS   B 1 280 ? -2.187  -14.575 33.393  1.00 36.24  ? 266 HIS   F CB  1 
ATOM   4320 C  CG  . HIS   B 1 280 ? -1.674  -15.968 33.195  1.00 40.23  ? 266 HIS   F CG  1 
ATOM   4321 N  ND1 . HIS   B 1 280 ? -1.914  -17.014 34.100  1.00 33.97  ? 266 HIS   F ND1 1 
ATOM   4322 C  CD2 . HIS   B 1 280 ? -0.946  -16.501 32.184  1.00 34.06  ? 266 HIS   F CD2 1 
ATOM   4323 C  CE1 . HIS   B 1 280 ? -1.313  -18.095 33.651  1.00 35.63  ? 266 HIS   F CE1 1 
ATOM   4324 N  NE2 . HIS   B 1 280 ? -0.689  -17.790 32.510  1.00 35.87  ? 266 HIS   F NE2 1 
ATOM   4325 N  N   . ASP   B 1 281 ? -5.338  -12.626 33.987  1.00 37.60  ? 267 ASP   F N   1 
ATOM   4326 C  CA  . ASP   B 1 281 ? -5.810  -11.239 34.251  1.00 39.04  ? 267 ASP   F CA  1 
ATOM   4327 C  C   . ASP   B 1 281 ? -6.248  -11.157 35.722  1.00 38.22  ? 267 ASP   F C   1 
ATOM   4328 O  O   . ASP   B 1 281 ? -7.340  -11.627 36.033  1.00 37.92  ? 267 ASP   F O   1 
ATOM   4329 C  CB  . ASP   B 1 281 ? -6.942  -10.831 33.324  1.00 40.49  ? 267 ASP   F CB  1 
ATOM   4330 C  CG  . ASP   B 1 281 ? -7.252  -9.332  33.366  1.00 42.81  ? 267 ASP   F CG  1 
ATOM   4331 O  OD1 . ASP   B 1 281 ? -7.294  -8.749  34.466  1.00 44.04  ? 267 ASP   F OD1 1 
ATOM   4332 O  OD2 . ASP   B 1 281 ? -7.400  -8.773  32.291  1.00 47.87  ? 267 ASP   F OD2 1 
ATOM   4333 N  N   . ALA   B 1 282 ? -5.400  -10.613 36.583  1.00 38.55  ? 268 ALA   F N   1 
ATOM   4334 C  CA  . ALA   B 1 282 ? -5.690  -10.453 38.037  1.00 42.82  ? 268 ALA   F CA  1 
ATOM   4335 C  C   . ALA   B 1 282 ? -7.066  -9.766  38.233  1.00 39.56  ? 268 ALA   F C   1 
ATOM   4336 O  O   . ALA   B 1 282 ? -7.848  -10.240 39.052  1.00 42.19  ? 268 ALA   F O   1 
ATOM   4337 C  CB  . ALA   B 1 282 ? -4.551  -9.700  38.729  1.00 39.52  ? 268 ALA   F CB  1 
ATOM   4338 N  N   . GLU   B 1 283 ? -7.375  -8.698  37.512  1.00 39.65  ? 269 GLU   F N   1 
ATOM   4339 C  CA  . GLU   B 1 283 ? -8.642  -7.942  37.751  1.00 43.79  ? 269 GLU   F CA  1 
ATOM   4340 C  C   . GLU   B 1 283 ? -9.825  -8.798  37.291  1.00 47.46  ? 269 GLU   F C   1 
ATOM   4341 O  O   . GLU   B 1 283 ? -10.800 -8.918  38.037  1.00 40.64  ? 269 GLU   F O   1 
ATOM   4342 C  CB  . GLU   B 1 283 ? -8.582  -6.551  37.123  1.00 48.70  ? 269 GLU   F CB  1 
ATOM   4343 C  CG  . GLU   B 1 283 ? -7.512  -5.706  37.790  1.00 66.59  ? 269 GLU   F CG  1 
ATOM   4344 C  CD  . GLU   B 1 283 ? -7.349  -4.279  37.297  1.00 90.84  ? 269 GLU   F CD  1 
ATOM   4345 O  OE1 . GLU   B 1 283 ? -7.790  -3.977  36.159  1.00 104.84 ? 269 GLU   F OE1 1 
ATOM   4346 O  OE2 . GLU   B 1 283 ? -6.757  -3.470  38.053  1.00 111.48 ? 269 GLU   F OE2 1 
ATOM   4347 N  N   . GLN   B 1 284 ? -9.756  -9.434  36.121  1.00 41.27  ? 270 GLN   F N   1 
ATOM   4348 C  CA  . GLN   B 1 284 ? -10.863 -10.327 35.692  1.00 39.75  ? 270 GLN   F CA  1 
ATOM   4349 C  C   . GLN   B 1 284 ? -11.045 -11.503 36.671  1.00 37.96  ? 270 GLN   F C   1 
ATOM   4350 O  O   . GLN   B 1 284 ? -12.214 -11.900 36.956  1.00 39.38  ? 270 GLN   F O   1 
ATOM   4351 C  CB  . GLN   B 1 284 ? -10.606 -10.864 34.290  1.00 38.59  ? 270 GLN   F CB  1 
ATOM   4352 C  CG  . GLN   B 1 284 ? -11.748 -11.725 33.755  1.00 38.06  ? 270 GLN   F CG  1 
ATOM   4353 C  CD  . GLN   B 1 284 ? -11.470 -12.256 32.355  1.00 43.69  ? 270 GLN   F CD  1 
ATOM   4354 O  OE1 . GLN   B 1 284 ? -10.483 -12.943 32.104  1.00 39.39  ? 270 GLN   F OE1 1 
ATOM   4355 N  NE2 . GLN   B 1 284 ? -12.339 -11.921 31.415  1.00 39.84  ? 270 GLN   F NE2 1 
ATOM   4356 N  N   . PHE   B 1 285 ? -9.952  -12.104 37.124  1.00 34.84  ? 271 PHE   F N   1 
ATOM   4357 C  CA  . PHE   B 1 285 ? -9.999  -13.338 37.940  1.00 39.35  ? 271 PHE   F CA  1 
ATOM   4358 C  C   . PHE   B 1 285 ? -10.680 -13.022 39.284  1.00 42.52  ? 271 PHE   F C   1 
ATOM   4359 O  O   . PHE   B 1 285 ? -11.477 -13.848 39.819  1.00 39.75  ? 271 PHE   F O   1 
ATOM   4360 C  CB  . PHE   B 1 285 ? -8.584  -13.855 38.169  1.00 40.98  ? 271 PHE   F CB  1 
ATOM   4361 C  CG  . PHE   B 1 285 ? -8.555  -15.143 38.920  1.00 39.50  ? 271 PHE   F CG  1 
ATOM   4362 C  CD1 . PHE   B 1 285 ? -8.916  -16.324 38.291  1.00 43.16  ? 271 PHE   F CD1 1 
ATOM   4363 C  CD2 . PHE   B 1 285 ? -8.181  -15.175 40.258  1.00 41.64  ? 271 PHE   F CD2 1 
ATOM   4364 C  CE1 . PHE   B 1 285 ? -8.889  -17.525 38.988  1.00 41.92  ? 271 PHE   F CE1 1 
ATOM   4365 C  CE2 . PHE   B 1 285 ? -8.140  -16.377 40.943  1.00 42.52  ? 271 PHE   F CE2 1 
ATOM   4366 C  CZ  . PHE   B 1 285 ? -8.503  -17.548 40.307  1.00 44.89  ? 271 PHE   F CZ  1 
ATOM   4367 N  N   . LYS   B 1 286 ? -10.406 -11.831 39.812  1.00 46.17  ? 272 LYS   F N   1 
ATOM   4368 C  CA  . LYS   B 1 286 ? -11.005 -11.377 41.102  1.00 51.98  ? 272 LYS   F CA  1 
ATOM   4369 C  C   . LYS   B 1 286 ? -12.521 -11.464 41.004  1.00 45.50  ? 272 LYS   F C   1 
ATOM   4370 O  O   . LYS   B 1 286 ? -13.171 -11.779 42.005  1.00 47.28  ? 272 LYS   F O   1 
ATOM   4371 C  CB  . LYS   B 1 286 ? -10.664 -9.914  41.387  1.00 57.45  ? 272 LYS   F CB  1 
ATOM   4372 C  CG  . LYS   B 1 286 ? -9.510  -9.704  42.343  1.00 73.07  ? 272 LYS   F CG  1 
ATOM   4373 C  CD  . LYS   B 1 286 ? -9.571  -8.370  43.051  1.00 82.01  ? 272 LYS   F CD  1 
ATOM   4374 C  CE  . LYS   B 1 286 ? -9.529  -8.521  44.560  1.00 91.01  ? 272 LYS   F CE  1 
ATOM   4375 N  NZ  . LYS   B 1 286 ? -9.866  -7.253  45.247  1.00 97.36  ? 272 LYS   F NZ  1 
ATOM   4376 N  N   . LYS   B 1 287 ? -13.067 -11.160 39.835  1.00 41.09  ? 273 LYS   F N   1 
ATOM   4377 C  CA  . LYS   B 1 287 ? -14.530 -11.039 39.633  1.00 45.47  ? 273 LYS   F CA  1 
ATOM   4378 C  C   . LYS   B 1 287 ? -15.144 -12.424 39.420  1.00 44.29  ? 273 LYS   F C   1 
ATOM   4379 O  O   . LYS   B 1 287 ? -16.362 -12.494 39.526  1.00 43.19  ? 273 LYS   F O   1 
ATOM   4380 C  CB  . LYS   B 1 287 ? -14.848 -10.046 38.508  1.00 52.61  ? 273 LYS   F CB  1 
ATOM   4381 C  CG  . LYS   B 1 287 ? -14.350 -8.628  38.810  1.00 65.40  ? 273 LYS   F CG  1 
ATOM   4382 C  CD  . LYS   B 1 287 ? -14.276 -7.686  37.627  1.00 74.71  ? 273 LYS   F CD  1 
ATOM   4383 C  CE  . LYS   B 1 287 ? -15.578 -6.959  37.370  1.00 87.22  ? 273 LYS   F CE  1 
ATOM   4384 N  NZ  . LYS   B 1 287 ? -15.725 -6.576  35.943  1.00 100.67 ? 273 LYS   F NZ  1 
ATOM   4385 N  N   . PHE   B 1 288 ? -14.376 -13.482 39.116  1.00 37.45  ? 274 PHE   F N   1 
ATOM   4386 C  CA  . PHE   B 1 288 ? -14.967 -14.819 38.826  1.00 37.53  ? 274 PHE   F CA  1 
ATOM   4387 C  C   . PHE   B 1 288 ? -15.553 -15.346 40.136  1.00 39.13  ? 274 PHE   F C   1 
ATOM   4388 O  O   . PHE   B 1 288 ? -14.998 -15.042 41.189  1.00 44.14  ? 274 PHE   F O   1 
ATOM   4389 C  CB  . PHE   B 1 288 ? -13.944 -15.847 38.304  1.00 38.99  ? 274 PHE   F CB  1 
ATOM   4390 C  CG  . PHE   B 1 288 ? -13.408 -15.627 36.897  1.00 39.17  ? 274 PHE   F CG  1 
ATOM   4391 C  CD1 . PHE   B 1 288 ? -14.168 -15.024 35.901  1.00 42.15  ? 274 PHE   F CD1 1 
ATOM   4392 C  CD2 . PHE   B 1 288 ? -12.134 -16.060 36.564  1.00 36.73  ? 274 PHE   F CD2 1 
ATOM   4393 C  CE1 . PHE   B 1 288 ? -13.646 -14.815 34.622  1.00 44.00  ? 274 PHE   F CE1 1 
ATOM   4394 C  CE2 . PHE   B 1 288 ? -11.614 -15.874 35.285  1.00 41.00  ? 274 PHE   F CE2 1 
ATOM   4395 C  CZ  . PHE   B 1 288 ? -12.370 -15.245 34.315  1.00 41.82  ? 274 PHE   F CZ  1 
ATOM   4396 N  N   . ARG   B 1 289 ? -16.571 -16.185 40.048  1.00 42.28  ? 275 ARG   F N   1 
ATOM   4397 C  CA  . ARG   B 1 289 ? -17.016 -17.053 41.161  1.00 42.61  ? 275 ARG   F CA  1 
ATOM   4398 C  C   . ARG   B 1 289 ? -16.122 -18.284 41.093  1.00 39.67  ? 275 ARG   F C   1 
ATOM   4399 O  O   . ARG   B 1 289 ? -16.162 -19.009 40.058  1.00 38.75  ? 275 ARG   F O   1 
ATOM   4400 C  CB  . ARG   B 1 289 ? -18.505 -17.360 40.925  1.00 52.52  ? 275 ARG   F CB  1 
ATOM   4401 C  CG  . ARG   B 1 289 ? -19.243 -18.104 42.028  1.00 55.98  ? 275 ARG   F CG  1 
ATOM   4402 C  CD  . ARG   B 1 289 ? -20.681 -18.431 41.614  1.00 56.69  ? 275 ARG   F CD  1 
ATOM   4403 N  NE  . ARG   B 1 289 ? -21.283 -17.288 40.969  1.00 64.22  ? 275 ARG   F NE  1 
ATOM   4404 C  CZ  . ARG   B 1 289 ? -21.873 -17.242 39.777  1.00 57.40  ? 275 ARG   F CZ  1 
ATOM   4405 N  NH1 . ARG   B 1 289 ? -22.034 -18.305 39.025  1.00 57.83  ? 275 ARG   F NH1 1 
ATOM   4406 N  NH2 . ARG   B 1 289 ? -22.330 -16.090 39.337  1.00 67.85  ? 275 ARG   F NH2 1 
ATOM   4407 N  N   . LYS   B 1 290 ? -15.335 -18.529 42.125  1.00 35.70  ? 276 LYS   F N   1 
ATOM   4408 C  CA  . LYS   B 1 290 ? -14.411 -19.688 42.168  1.00 35.92  ? 276 LYS   F CA  1 
ATOM   4409 C  C   . LYS   B 1 290 ? -15.064 -20.885 42.837  1.00 38.32  ? 276 LYS   F C   1 
ATOM   4410 O  O   . LYS   B 1 290 ? -16.171 -20.737 43.407  1.00 36.99  ? 276 LYS   F O   1 
ATOM   4411 C  CB  . LYS   B 1 290 ? -13.118 -19.382 42.900  1.00 41.54  ? 276 LYS   F CB  1 
ATOM   4412 C  CG  . LYS   B 1 290 ? -12.755 -17.928 42.898  1.00 55.31  ? 276 LYS   F CG  1 
ATOM   4413 C  CD  . LYS   B 1 290 ? -12.102 -17.488 41.648  1.00 45.45  ? 276 LYS   F CD  1 
ATOM   4414 C  CE  . LYS   B 1 290 ? -11.315 -16.240 42.013  1.00 53.50  ? 276 LYS   F CE  1 
ATOM   4415 N  NZ  . LYS   B 1 290 ? -12.213 -15.157 42.466  1.00 48.04  ? 276 LYS   F NZ  1 
ATOM   4416 N  N   . SER   B 1 291 ? -14.332 -22.002 42.846  1.00 38.05  ? 277 SER   F N   1 
ATOM   4417 C  CA  . SER   B 1 291 ? -14.852 -23.346 43.182  1.00 35.70  ? 277 SER   F CA  1 
ATOM   4418 C  C   . SER   B 1 291 ? -15.240 -23.381 44.673  1.00 37.50  ? 277 SER   F C   1 
ATOM   4419 O  O   . SER   B 1 291 ? -15.929 -24.372 45.078  1.00 38.88  ? 277 SER   F O   1 
ATOM   4420 C  CB  . SER   B 1 291 ? -13.865 -24.453 42.849  1.00 32.21  ? 277 SER   F CB  1 
ATOM   4421 O  OG  . SER   B 1 291 ? -12.631 -24.315 43.547  1.00 35.32  ? 277 SER   F OG  1 
ATOM   4422 N  N   . THR   B 1 292 ? -14.765 -22.421 45.472  1.00 35.96  ? 278 THR   F N   1 
ATOM   4423 C  CA  . THR   B 1 292 ? -15.096 -22.334 46.929  1.00 44.77  ? 278 THR   F CA  1 
ATOM   4424 C  C   . THR   B 1 292 ? -16.454 -21.649 47.134  1.00 45.11  ? 278 THR   F C   1 
ATOM   4425 O  O   . THR   B 1 292 ? -16.956 -21.688 48.273  1.00 43.33  ? 278 THR   F O   1 
ATOM   4426 C  CB  . THR   B 1 292 ? -13.966 -21.638 47.704  1.00 42.03  ? 278 THR   F CB  1 
ATOM   4427 O  OG1 . THR   B 1 292 ? -13.571 -20.530 46.885  1.00 52.01  ? 278 THR   F OG1 1 
ATOM   4428 C  CG2 . THR   B 1 292 ? -12.791 -22.569 47.938  1.00 48.51  ? 278 THR   F CG2 1 
ATOM   4429 N  N   . GLU   B 1 293 ? -17.031 -21.031 46.099  1.00 41.42  ? 279 GLU   F N   1 
ATOM   4430 C  CA  . GLU   B 1 293 ? -18.295 -20.247 46.211  1.00 43.32  ? 279 GLU   F CA  1 
ATOM   4431 C  C   . GLU   B 1 293 ? -19.356 -20.818 45.278  1.00 39.39  ? 279 GLU   F C   1 
ATOM   4432 O  O   . GLU   B 1 293 ? -20.536 -20.531 45.504  1.00 36.22  ? 279 GLU   F O   1 
ATOM   4433 C  CB  . GLU   B 1 293 ? -18.089 -18.765 45.863  1.00 46.22  ? 279 GLU   F CB  1 
ATOM   4434 C  CG  . GLU   B 1 293 ? -17.341 -17.942 46.890  1.00 55.08  ? 279 GLU   F CG  1 
ATOM   4435 C  CD  . GLU   B 1 293 ? -15.887 -17.758 46.474  1.00 76.00  ? 279 GLU   F CD  1 
ATOM   4436 O  OE1 . GLU   B 1 293 ? -15.020 -18.183 47.288  1.00 82.29  ? 279 GLU   F OE1 1 
ATOM   4437 O  OE2 . GLU   B 1 293 ? -15.615 -17.247 45.292  1.00 64.18  ? 279 GLU   F OE2 1 
ATOM   4438 N  N   . GLY   B 1 294 ? -18.965 -21.493 44.192  1.00 35.53  ? 280 GLY   F N   1 
ATOM   4439 C  CA  . GLY   B 1 294 ? -19.922 -22.058 43.238  1.00 35.92  ? 280 GLY   F CA  1 
ATOM   4440 C  C   . GLY   B 1 294 ? -19.373 -22.222 41.822  1.00 37.17  ? 280 GLY   F C   1 
ATOM   4441 O  O   . GLY   B 1 294 ? -18.218 -22.645 41.672  1.00 35.92  ? 280 GLY   F O   1 
ATOM   4442 N  N   . TYR   B 1 295 ? -20.229 -21.985 40.842  1.00 36.18  ? 281 TYR   F N   1 
ATOM   4443 C  CA  . TYR   B 1 295 ? -20.102 -22.529 39.466  1.00 36.28  ? 281 TYR   F CA  1 
ATOM   4444 C  C   . TYR   B 1 295 ? -20.976 -21.700 38.538  1.00 38.94  ? 281 TYR   F C   1 
ATOM   4445 O  O   . TYR   B 1 295 ? -21.756 -20.896 39.018  1.00 37.96  ? 281 TYR   F O   1 
ATOM   4446 C  CB  . TYR   B 1 295 ? -20.491 -24.007 39.397  1.00 36.35  ? 281 TYR   F CB  1 
ATOM   4447 C  CG  . TYR   B 1 295 ? -21.690 -24.381 40.233  1.00 37.85  ? 281 TYR   F CG  1 
ATOM   4448 C  CD1 . TYR   B 1 295 ? -22.970 -23.969 39.892  1.00 40.72  ? 281 TYR   F CD1 1 
ATOM   4449 C  CD2 . TYR   B 1 295 ? -21.533 -25.102 41.415  1.00 43.43  ? 281 TYR   F CD2 1 
ATOM   4450 C  CE1 . TYR   B 1 295 ? -24.075 -24.270 40.679  1.00 38.21  ? 281 TYR   F CE1 1 
ATOM   4451 C  CE2 . TYR   B 1 295 ? -22.639 -25.460 42.182  1.00 38.02  ? 281 TYR   F CE2 1 
ATOM   4452 C  CZ  . TYR   B 1 295 ? -23.910 -25.037 41.824  1.00 41.46  ? 281 TYR   F CZ  1 
ATOM   4453 O  OH  . TYR   B 1 295 ? -24.987 -25.402 42.598  1.00 44.32  ? 281 TYR   F OH  1 
ATOM   4454 N  N   . TYR   B 1 296 ? -20.825 -21.937 37.240  1.00 36.82  ? 282 TYR   F N   1 
ATOM   4455 C  CA  . TYR   B 1 296 ? -21.597 -21.296 36.168  1.00 40.84  ? 282 TYR   F CA  1 
ATOM   4456 C  C   . TYR   B 1 296 ? -22.451 -22.387 35.522  1.00 38.63  ? 282 TYR   F C   1 
ATOM   4457 O  O   . TYR   B 1 296 ? -21.907 -23.451 35.193  1.00 37.41  ? 282 TYR   F O   1 
ATOM   4458 C  CB  . TYR   B 1 296 ? -20.641 -20.600 35.194  1.00 37.72  ? 282 TYR   F CB  1 
ATOM   4459 C  CG  . TYR   B 1 296 ? -19.898 -19.429 35.775  1.00 38.49  ? 282 TYR   F CG  1 
ATOM   4460 C  CD1 . TYR   B 1 296 ? -18.726 -19.633 36.477  1.00 40.61  ? 282 TYR   F CD1 1 
ATOM   4461 C  CD2 . TYR   B 1 296 ? -20.363 -18.122 35.654  1.00 41.54  ? 282 TYR   F CD2 1 
ATOM   4462 C  CE1 . TYR   B 1 296 ? -18.007 -18.576 37.003  1.00 35.85  ? 282 TYR   F CE1 1 
ATOM   4463 C  CE2 . TYR   B 1 296 ? -19.665 -17.044 36.195  1.00 40.80  ? 282 TYR   F CE2 1 
ATOM   4464 C  CZ  . TYR   B 1 296 ? -18.461 -17.280 36.844  1.00 41.41  ? 282 TYR   F CZ  1 
ATOM   4465 O  OH  . TYR   B 1 296 ? -17.759 -16.290 37.452  1.00 40.84  ? 282 TYR   F OH  1 
ATOM   4466 N  N   . GLU   B 1 297 ? -23.760 -22.166 35.434  1.00 40.06  ? 283 GLU   F N   1 
ATOM   4467 C  CA  . GLU   B 1 297 ? -24.614 -22.950 34.511  1.00 44.62  ? 283 GLU   F CA  1 
ATOM   4468 C  C   . GLU   B 1 297 ? -25.102 -22.012 33.369  1.00 38.38  ? 283 GLU   F C   1 
ATOM   4469 O  O   . GLU   B 1 297 ? -25.859 -22.808 32.680  1.00 43.10  ? 283 GLU   F O   1 
ATOM   4470 C  CB  . GLU   B 1 297 ? -25.627 -23.828 35.263  1.00 50.46  ? 283 GLU   F CB  1 
ATOM   4471 C  CG  . GLU   B 1 297 ? -26.344 -23.246 36.447  1.00 63.05  ? 283 GLU   F CG  1 
ATOM   4472 C  CD  . GLU   B 1 297 ? -27.241 -24.259 37.175  1.00 56.98  ? 283 GLU   F CD  1 
ATOM   4473 O  OE1 . GLU   B 1 297 ? -28.447 -24.117 37.083  1.00 58.94  ? 283 GLU   F OE1 1 
ATOM   4474 O  OE2 . GLU   B 1 297 ? -26.730 -25.155 37.861  1.00 52.42  ? 283 GLU   F OE2 1 
ATOM   4475 N  N   . ALA   C 1 22  ? 39.882  -31.716 -1.833  1.00 67.22  ? 8   ALA   L N   1 
ATOM   4476 C  CA  . ALA   C 1 22  ? 39.662  -32.841 -0.826  1.00 69.63  ? 8   ALA   L CA  1 
ATOM   4477 C  C   . ALA   C 1 22  ? 39.713  -34.190 -1.557  1.00 62.59  ? 8   ALA   L C   1 
ATOM   4478 O  O   . ALA   C 1 22  ? 39.126  -34.254 -2.666  1.00 56.33  ? 8   ALA   L O   1 
ATOM   4479 C  CB  . ALA   C 1 22  ? 38.338  -32.664 -0.096  1.00 63.02  ? 8   ALA   L CB  1 
ATOM   4480 N  N   . ARG   C 1 23  ? 40.350  -35.207 -0.939  1.00 63.33  ? 9   ARG   L N   1 
ATOM   4481 C  CA  . ARG   C 1 23  ? 40.509  -36.611 -1.432  1.00 55.59  ? 9   ARG   L CA  1 
ATOM   4482 C  C   . ARG   C 1 23  ? 39.921  -37.572 -0.395  1.00 53.34  ? 9   ARG   L C   1 
ATOM   4483 O  O   . ARG   C 1 23  ? 40.623  -38.350 0.266   1.00 44.29  ? 9   ARG   L O   1 
ATOM   4484 C  CB  . ARG   C 1 23  ? 41.979  -36.968 -1.701  1.00 61.16  ? 9   ARG   L CB  1 
ATOM   4485 C  CG  . ARG   C 1 23  ? 42.712  -36.114 -2.736  1.00 68.42  ? 9   ARG   L CG  1 
ATOM   4486 C  CD  . ARG   C 1 23  ? 41.887  -35.777 -3.965  1.00 85.55  ? 9   ARG   L CD  1 
ATOM   4487 N  NE  . ARG   C 1 23  ? 42.586  -35.830 -5.256  1.00 104.60 ? 9   ARG   L NE  1 
ATOM   4488 C  CZ  . ARG   C 1 23  ? 42.340  -35.030 -6.308  1.00 99.24  ? 9   ARG   L CZ  1 
ATOM   4489 N  NH1 . ARG   C 1 23  ? 41.441  -34.058 -6.240  1.00 100.83 ? 9   ARG   L NH1 1 
ATOM   4490 N  NH2 . ARG   C 1 23  ? 43.019  -35.187 -7.430  1.00 102.08 ? 9   ARG   L NH2 1 
ATOM   4491 N  N   . PRO   C 1 24  ? 38.583  -37.572 -0.242  1.00 47.61  ? 10  PRO   L N   1 
ATOM   4492 C  CA  . PRO   C 1 24  ? 37.926  -38.467 0.697   1.00 44.58  ? 10  PRO   L CA  1 
ATOM   4493 C  C   . PRO   C 1 24  ? 37.978  -39.929 0.274   1.00 41.87  ? 10  PRO   L C   1 
ATOM   4494 O  O   . PRO   C 1 24  ? 38.198  -40.225 -0.878  1.00 43.59  ? 10  PRO   L O   1 
ATOM   4495 C  CB  . PRO   C 1 24  ? 36.442  -38.056 0.695   1.00 46.67  ? 10  PRO   L CB  1 
ATOM   4496 C  CG  . PRO   C 1 24  ? 36.306  -36.939 -0.309  1.00 49.96  ? 10  PRO   L CG  1 
ATOM   4497 C  CD  . PRO   C 1 24  ? 37.647  -36.697 -0.963  1.00 50.78  ? 10  PRO   L CD  1 
ATOM   4498 N  N   . LYS   C 1 25  ? 37.697  -40.804 1.220   1.00 39.68  ? 11  LYS   L N   1 
ATOM   4499 C  CA  . LYS   C 1 25  ? 37.502  -42.243 0.957   1.00 36.73  ? 11  LYS   L CA  1 
ATOM   4500 C  C   . LYS   C 1 25  ? 36.132  -42.674 1.476   1.00 35.40  ? 11  LYS   L C   1 
ATOM   4501 O  O   . LYS   C 1 25  ? 35.833  -42.474 2.679   1.00 36.90  ? 11  LYS   L O   1 
ATOM   4502 C  CB  . LYS   C 1 25  ? 38.626  -43.058 1.622   1.00 41.08  ? 11  LYS   L CB  1 
ATOM   4503 C  CG  . LYS   C 1 25  ? 40.021  -42.955 0.986   1.00 39.10  ? 11  LYS   L CG  1 
ATOM   4504 C  CD  . LYS   C 1 25  ? 41.016  -43.699 1.865   1.00 45.96  ? 11  LYS   L CD  1 
ATOM   4505 C  CE  . LYS   C 1 25  ? 42.318  -44.020 1.187   1.00 47.64  ? 11  LYS   L CE  1 
ATOM   4506 N  NZ  . LYS   C 1 25  ? 43.001  -42.764 0.854   1.00 50.25  ? 11  LYS   L NZ  1 
ATOM   4507 N  N   . LEU   C 1 26  ? 35.344  -43.312 0.630   1.00 37.14  ? 12  LEU   L N   1 
ATOM   4508 C  CA  . LEU   C 1 26  ? 33.968  -43.751 0.984   1.00 35.08  ? 12  LEU   L CA  1 
ATOM   4509 C  C   . LEU   C 1 26  ? 33.944  -45.278 1.082   1.00 33.67  ? 12  LEU   L C   1 
ATOM   4510 O  O   . LEU   C 1 26  ? 34.446  -45.949 0.143   1.00 35.35  ? 12  LEU   L O   1 
ATOM   4511 C  CB  . LEU   C 1 26  ? 32.974  -43.212 -0.054  1.00 34.90  ? 12  LEU   L CB  1 
ATOM   4512 C  CG  . LEU   C 1 26  ? 31.496  -43.574 0.124   1.00 35.93  ? 12  LEU   L CG  1 
ATOM   4513 C  CD1 . LEU   C 1 26  ? 30.605  -42.554 -0.593  1.00 38.34  ? 12  LEU   L CD1 1 
ATOM   4514 C  CD2 . LEU   C 1 26  ? 31.160  -44.968 -0.395  1.00 35.31  ? 12  LEU   L CD2 1 
ATOM   4515 N  N   . TYR   C 1 27  ? 33.453  -45.771 2.215   1.00 31.85  ? 13  TYR   L N   1 
ATOM   4516 C  CA  . TYR   C 1 27  ? 33.391  -47.210 2.561   1.00 33.32  ? 13  TYR   L CA  1 
ATOM   4517 C  C   . TYR   C 1 27  ? 31.946  -47.671 2.676   1.00 37.11  ? 13  TYR   L C   1 
ATOM   4518 O  O   . TYR   C 1 27  ? 31.121  -47.020 3.359   1.00 36.67  ? 13  TYR   L O   1 
ATOM   4519 C  CB  . TYR   C 1 27  ? 34.067  -47.492 3.902   1.00 33.34  ? 13  TYR   L CB  1 
ATOM   4520 C  CG  . TYR   C 1 27  ? 35.509  -47.093 4.017   1.00 37.67  ? 13  TYR   L CG  1 
ATOM   4521 C  CD1 . TYR   C 1 27  ? 35.872  -45.775 4.277   1.00 38.78  ? 13  TYR   L CD1 1 
ATOM   4522 C  CD2 . TYR   C 1 27  ? 36.519  -48.056 3.923   1.00 38.81  ? 13  TYR   L CD2 1 
ATOM   4523 C  CE1 . TYR   C 1 27  ? 37.202  -45.408 4.408   1.00 38.64  ? 13  TYR   L CE1 1 
ATOM   4524 C  CE2 . TYR   C 1 27  ? 37.845  -47.701 4.055   1.00 36.77  ? 13  TYR   L CE2 1 
ATOM   4525 C  CZ  . TYR   C 1 27  ? 38.182  -46.387 4.325   1.00 40.29  ? 13  TYR   L CZ  1 
ATOM   4526 O  OH  . TYR   C 1 27  ? 39.497  -46.062 4.382   1.00 43.70  ? 13  TYR   L OH  1 
ATOM   4527 N  N   . VAL   C 1 28  ? 31.662  -48.813 2.079   1.00 36.69  ? 14  VAL   L N   1 
ATOM   4528 C  CA  . VAL   C 1 28  ? 30.396  -49.566 2.251   1.00 33.99  ? 14  VAL   L CA  1 
ATOM   4529 C  C   . VAL   C 1 28  ? 30.625  -50.634 3.316   1.00 39.32  ? 14  VAL   L C   1 
ATOM   4530 O  O   . VAL   C 1 28  ? 31.479  -51.548 3.083   1.00 35.92  ? 14  VAL   L O   1 
ATOM   4531 C  CB  . VAL   C 1 28  ? 29.980  -50.185 0.912   1.00 37.14  ? 14  VAL   L CB  1 
ATOM   4532 C  CG1 . VAL   C 1 28  ? 28.747  -51.062 1.046   1.00 37.95  ? 14  VAL   L CG1 1 
ATOM   4533 C  CG2 . VAL   C 1 28  ? 29.774  -49.105 -0.134  1.00 42.15  ? 14  VAL   L CG2 1 
ATOM   4534 N  N   . MET   C 1 29  ? 29.850  -50.577 4.403   1.00 35.92  ? 15  MET   L N   1 
ATOM   4535 C  CA  . MET   C 1 29  ? 29.970  -51.533 5.523   1.00 35.07  ? 15  MET   L CA  1 
ATOM   4536 C  C   . MET   C 1 29  ? 28.767  -52.468 5.544   1.00 41.01  ? 15  MET   L C   1 
ATOM   4537 O  O   . MET   C 1 29  ? 27.596  -52.005 5.551   1.00 39.06  ? 15  MET   L O   1 
ATOM   4538 C  CB  . MET   C 1 29  ? 30.132  -50.784 6.843   1.00 38.61  ? 15  MET   L CB  1 
ATOM   4539 C  CG  . MET   C 1 29  ? 31.441  -49.976 6.894   1.00 37.84  ? 15  MET   L CG  1 
ATOM   4540 S  SD  . MET   C 1 29  ? 31.609  -48.989 8.392   1.00 40.00  ? 15  MET   L SD  1 
ATOM   4541 C  CE  . MET   C 1 29  ? 30.407  -47.693 8.022   1.00 43.74  ? 15  MET   L CE  1 
ATOM   4542 N  N   . ASP   C 1 30  ? 29.052  -53.763 5.505   1.00 35.88  ? 16  ASP   L N   1 
ATOM   4543 C  CA  . ASP   C 1 30  ? 28.032  -54.845 5.504   1.00 39.63  ? 16  ASP   L CA  1 
ATOM   4544 C  C   . ASP   C 1 30  ? 27.548  -55.042 6.946   1.00 40.49  ? 16  ASP   L C   1 
ATOM   4545 O  O   . ASP   C 1 30  ? 28.361  -55.492 7.770   1.00 37.84  ? 16  ASP   L O   1 
ATOM   4546 C  CB  . ASP   C 1 30  ? 28.656  -56.100 4.883   1.00 44.62  ? 16  ASP   L CB  1 
ATOM   4547 C  CG  . ASP   C 1 30  ? 27.703  -57.251 4.639   1.00 47.39  ? 16  ASP   L CG  1 
ATOM   4548 O  OD1 . ASP   C 1 30  ? 26.696  -57.341 5.352   1.00 44.78  ? 16  ASP   L OD1 1 
ATOM   4549 O  OD2 . ASP   C 1 30  ? 27.946  -58.004 3.698   1.00 46.70  ? 16  ASP   L OD2 1 
ATOM   4550 N  N   . ASN   C 1 31  ? 26.268  -54.749 7.249   1.00 37.16  ? 17  ASN   L N   1 
ATOM   4551 C  CA  . ASN   C 1 31  ? 25.714  -54.865 8.628   1.00 34.18  ? 17  ASN   L CA  1 
ATOM   4552 C  C   . ASN   C 1 31  ? 24.676  -55.981 8.655   1.00 39.46  ? 17  ASN   L C   1 
ATOM   4553 O  O   . ASN   C 1 31  ? 23.758  -55.950 9.491   1.00 42.75  ? 17  ASN   L O   1 
ATOM   4554 C  CB  . ASN   C 1 31  ? 25.198  -53.533 9.175   1.00 35.97  ? 17  ASN   L CB  1 
ATOM   4555 C  CG  . ASN   C 1 31  ? 26.197  -52.415 9.053   1.00 37.94  ? 17  ASN   L CG  1 
ATOM   4556 O  OD1 . ASN   C 1 31  ? 25.955  -51.396 8.401   1.00 38.03  ? 17  ASN   L OD1 1 
ATOM   4557 N  ND2 . ASN   C 1 31  ? 27.349  -52.592 9.669   1.00 41.29  ? 17  ASN   L ND2 1 
ATOM   4558 N  N   . GLY   C 1 32  ? 24.850  -56.992 7.817   1.00 38.87  ? 18  GLY   L N   1 
ATOM   4559 C  CA  . GLY   C 1 32  ? 24.034  -58.213 7.923   1.00 39.18  ? 18  GLY   L CA  1 
ATOM   4560 C  C   . GLY   C 1 32  ? 22.861  -58.223 6.961   1.00 37.62  ? 18  GLY   L C   1 
ATOM   4561 O  O   . GLY   C 1 32  ? 22.859  -57.424 6.016   1.00 38.62  ? 18  GLY   L O   1 
ATOM   4562 N  N   . ARG   C 1 33  ? 21.906  -59.102 7.215   1.00 37.27  ? 19  ARG   L N   1 
ATOM   4563 C  CA  . ARG   C 1 33  ? 20.815  -59.468 6.277   1.00 43.34  ? 19  ARG   L CA  1 
ATOM   4564 C  C   . ARG   C 1 33  ? 19.494  -59.474 7.059   1.00 39.70  ? 19  ARG   L C   1 
ATOM   4565 O  O   . ARG   C 1 33  ? 19.463  -59.912 8.248   1.00 40.92  ? 19  ARG   L O   1 
ATOM   4566 C  CB  . ARG   C 1 33  ? 21.048  -60.845 5.637   1.00 44.29  ? 19  ARG   L CB  1 
ATOM   4567 C  CG  . ARG   C 1 33  ? 22.334  -61.015 4.841   1.00 46.31  ? 19  ARG   L CG  1 
ATOM   4568 C  CD  . ARG   C 1 33  ? 22.361  -60.353 3.473   1.00 50.25  ? 19  ARG   L CD  1 
ATOM   4569 N  NE  . ARG   C 1 33  ? 23.711  -60.388 2.899   1.00 48.31  ? 19  ARG   L NE  1 
ATOM   4570 C  CZ  . ARG   C 1 33  ? 24.726  -59.591 3.255   1.00 53.42  ? 19  ARG   L CZ  1 
ATOM   4571 N  NH1 . ARG   C 1 33  ? 24.583  -58.646 4.187   1.00 47.73  ? 19  ARG   L NH1 1 
ATOM   4572 N  NH2 . ARG   C 1 33  ? 25.911  -59.757 2.682   1.00 51.28  ? 19  ARG   L NH2 1 
ATOM   4573 N  N   . MET   C 1 34  ? 18.428  -58.993 6.433   1.00 40.92  ? 20  MET   L N   1 
ATOM   4574 C  CA  . MET   C 1 34  ? 17.044  -59.081 6.961   1.00 39.57  ? 20  MET   L CA  1 
ATOM   4575 C  C   . MET   C 1 34  ? 16.204  -59.854 5.952   1.00 38.77  ? 20  MET   L C   1 
ATOM   4576 O  O   . MET   C 1 34  ? 16.546  -59.902 4.749   1.00 42.01  ? 20  MET   L O   1 
ATOM   4577 C  CB  . MET   C 1 34  ? 16.508  -57.670 7.195   1.00 42.34  ? 20  MET   L CB  1 
ATOM   4578 C  CG  . MET   C 1 34  ? 15.124  -57.575 7.781   1.00 46.53  ? 20  MET   L CG  1 
ATOM   4579 S  SD  . MET   C 1 34  ? 14.744  -55.838 8.277   1.00 47.66  ? 20  MET   L SD  1 
ATOM   4580 C  CE  . MET   C 1 34  ? 15.754  -55.609 9.729   1.00 38.35  ? 20  MET   L CE  1 
ATOM   4581 N  N   . ARG   C 1 35  ? 15.137  -60.465 6.438   1.00 38.81  ? 21  ARG   L N   1 
ATOM   4582 C  CA  . ARG   C 1 35  ? 14.074  -61.051 5.606   1.00 41.10  ? 21  ARG   L CA  1 
ATOM   4583 C  C   . ARG   C 1 35  ? 12.731  -60.423 5.998   1.00 38.13  ? 21  ARG   L C   1 
ATOM   4584 O  O   . ARG   C 1 35  ? 12.519  -60.070 7.205   1.00 40.41  ? 21  ARG   L O   1 
ATOM   4585 C  CB  . ARG   C 1 35  ? 14.046  -62.569 5.799   1.00 44.86  ? 21  ARG   L CB  1 
ATOM   4586 C  CG  . ARG   C 1 35  ? 15.306  -63.246 5.267   1.00 50.89  ? 21  ARG   L CG  1 
ATOM   4587 C  CD  . ARG   C 1 35  ? 15.324  -64.745 5.497   1.00 52.30  ? 21  ARG   L CD  1 
ATOM   4588 N  NE  . ARG   C 1 35  ? 15.344  -65.094 6.921   1.00 57.42  ? 21  ARG   L NE  1 
ATOM   4589 C  CZ  . ARG   C 1 35  ? 14.820  -66.228 7.443   1.00 62.25  ? 21  ARG   L CZ  1 
ATOM   4590 N  NH1 . ARG   C 1 35  ? 14.245  -67.143 6.668   1.00 64.01  ? 21  ARG   L NH1 1 
ATOM   4591 N  NH2 . ARG   C 1 35  ? 14.880  -66.441 8.738   1.00 59.47  ? 21  ARG   L NH2 1 
ATOM   4592 N  N   . MET   C 1 36  ? 11.858  -60.325 5.021   1.00 38.49  ? 22  MET   L N   1 
ATOM   4593 C  CA  . MET   C 1 36  ? 10.446  -59.974 5.264   1.00 37.82  ? 22  MET   L CA  1 
ATOM   4594 C  C   . MET   C 1 36  ? 9.620   -60.401 4.061   1.00 39.17  ? 22  MET   L C   1 
ATOM   4595 O  O   . MET   C 1 36  ? 10.199  -60.685 2.993   1.00 39.33  ? 22  MET   L O   1 
ATOM   4596 C  CB  . MET   C 1 36  ? 10.325  -58.462 5.506   1.00 41.53  ? 22  MET   L CB  1 
ATOM   4597 C  CG  . MET   C 1 36  ? 10.598  -57.614 4.277   1.00 39.25  ? 22  MET   L CG  1 
ATOM   4598 S  SD  . MET   C 1 36  ? 10.706  -55.855 4.723   1.00 44.21  ? 22  MET   L SD  1 
ATOM   4599 C  CE  . MET   C 1 36  ? 11.024  -55.173 3.095   1.00 46.51  ? 22  MET   L CE  1 
ATOM   4600 N  N   . ASP   C 1 37  ? 8.300   -60.408 4.238   1.00 40.46  ? 23  ASP   L N   1 
ATOM   4601 C  CA  . ASP   C 1 37  ? 7.302   -60.573 3.150   1.00 37.78  ? 23  ASP   L CA  1 
ATOM   4602 C  C   . ASP   C 1 37  ? 7.674   -59.672 1.980   1.00 37.57  ? 23  ASP   L C   1 
ATOM   4603 O  O   . ASP   C 1 37  ? 7.867   -58.472 2.209   1.00 41.32  ? 23  ASP   L O   1 
ATOM   4604 C  CB  . ASP   C 1 37  ? 5.913   -60.244 3.714   1.00 38.63  ? 23  ASP   L CB  1 
ATOM   4605 C  CG  . ASP   C 1 37  ? 4.748   -60.675 2.874   1.00 35.11  ? 23  ASP   L CG  1 
ATOM   4606 O  OD1 . ASP   C 1 37  ? 4.852   -60.616 1.595   1.00 40.57  ? 23  ASP   L OD1 1 
ATOM   4607 O  OD2 . ASP   C 1 37  ? 3.696   -61.021 3.513   1.00 40.29  ? 23  ASP   L OD2 1 
ATOM   4608 N  N   . LYS   C 1 38  ? 7.689   -60.194 0.757   1.00 38.09  ? 24  LYS   L N   1 
ATOM   4609 C  CA  . LYS   C 1 38  ? 8.040   -59.388 -0.428  1.00 43.53  ? 24  LYS   L CA  1 
ATOM   4610 C  C   . LYS   C 1 38  ? 6.977   -58.299 -0.663  1.00 40.70  ? 24  LYS   L C   1 
ATOM   4611 O  O   . LYS   C 1 38  ? 7.319   -57.274 -1.291  1.00 42.47  ? 24  LYS   L O   1 
ATOM   4612 C  CB  . LYS   C 1 38  ? 8.163   -60.234 -1.694  1.00 45.81  ? 24  LYS   L CB  1 
ATOM   4613 C  CG  . LYS   C 1 38  ? 8.852   -59.518 -2.863  1.00 52.10  ? 24  LYS   L CG  1 
ATOM   4614 C  CD  . LYS   C 1 38  ? 9.001   -60.386 -4.091  1.00 66.06  ? 24  LYS   L CD  1 
ATOM   4615 C  CE  . LYS   C 1 38  ? 9.247   -59.630 -5.380  1.00 67.28  ? 24  LYS   L CE  1 
ATOM   4616 N  NZ  . LYS   C 1 38  ? 10.590  -59.034 -5.410  1.00 71.39  ? 24  LYS   L NZ  1 
ATOM   4617 N  N   . ASN   C 1 39  ? 5.741   -58.532 -0.235  1.00 42.95  ? 25  ASN   L N   1 
ATOM   4618 C  CA  . ASN   C 1 39  ? 4.648   -57.516 -0.315  1.00 41.12  ? 25  ASN   L CA  1 
ATOM   4619 C  C   . ASN   C 1 39  ? 5.051   -56.220 0.410   1.00 39.55  ? 25  ASN   L C   1 
ATOM   4620 O  O   . ASN   C 1 39  ? 4.610   -55.197 -0.047  1.00 40.97  ? 25  ASN   L O   1 
ATOM   4621 C  CB  . ASN   C 1 39  ? 3.301   -58.060 0.163   1.00 43.46  ? 25  ASN   L CB  1 
ATOM   4622 C  CG  . ASN   C 1 39  ? 2.640   -58.940 -0.885  1.00 47.58  ? 25  ASN   L CG  1 
ATOM   4623 O  OD1 . ASN   C 1 39  ? 2.093   -60.017 -0.593  1.00 59.51  ? 25  ASN   L OD1 1 
ATOM   4624 N  ND2 . ASN   C 1 39  ? 2.686   -58.493 -2.118  1.00 41.40  ? 25  ASN   L ND2 1 
ATOM   4625 N  N   . TRP   C 1 40  ? 5.841   -56.262 1.482   1.00 37.79  ? 26  TRP   L N   1 
ATOM   4626 C  CA  . TRP   C 1 40  ? 6.401   -55.034 2.104   1.00 39.70  ? 26  TRP   L CA  1 
ATOM   4627 C  C   . TRP   C 1 40  ? 7.269   -54.300 1.071   1.00 43.56  ? 26  TRP   L C   1 
ATOM   4628 O  O   . TRP   C 1 40  ? 7.269   -53.062 1.107   1.00 39.54  ? 26  TRP   L O   1 
ATOM   4629 C  CB  . TRP   C 1 40  ? 7.222   -55.271 3.379   1.00 37.66  ? 26  TRP   L CB  1 
ATOM   4630 C  CG  . TRP   C 1 40  ? 6.529   -55.864 4.571   1.00 41.64  ? 26  TRP   L CG  1 
ATOM   4631 C  CD1 . TRP   C 1 40  ? 6.829   -57.070 5.153   1.00 43.97  ? 26  TRP   L CD1 1 
ATOM   4632 C  CD2 . TRP   C 1 40  ? 5.537   -55.263 5.417   1.00 45.31  ? 26  TRP   L CD2 1 
ATOM   4633 N  NE1 . TRP   C 1 40  ? 6.052   -57.294 6.258   1.00 43.68  ? 26  TRP   L NE1 1 
ATOM   4634 C  CE2 . TRP   C 1 40  ? 5.245   -56.200 6.445   1.00 49.73  ? 26  TRP   L CE2 1 
ATOM   4635 C  CE3 . TRP   C 1 40  ? 4.848   -54.046 5.406   1.00 48.10  ? 26  TRP   L CE3 1 
ATOM   4636 C  CZ2 . TRP   C 1 40  ? 4.308   -55.949 7.445   1.00 47.38  ? 26  TRP   L CZ2 1 
ATOM   4637 C  CZ3 . TRP   C 1 40  ? 3.920   -53.804 6.396   1.00 47.35  ? 26  TRP   L CZ3 1 
ATOM   4638 C  CH2 . TRP   C 1 40  ? 3.634   -54.752 7.382   1.00 50.01  ? 26  TRP   L CH2 1 
ATOM   4639 N  N   . MET   C 1 41  ? 8.077   -55.027 0.296   1.00 40.95  ? 27  MET   L N   1 
ATOM   4640 C  CA  . MET   C 1 41  ? 9.103   -54.464 -0.612  1.00 43.73  ? 27  MET   L CA  1 
ATOM   4641 C  C   . MET   C 1 41  ? 8.427   -53.938 -1.875  1.00 44.13  ? 27  MET   L C   1 
ATOM   4642 O  O   . MET   C 1 41  ? 8.741   -52.800 -2.288  1.00 38.58  ? 27  MET   L O   1 
ATOM   4643 C  CB  . MET   C 1 41  ? 10.121  -55.548 -0.992  1.00 51.52  ? 27  MET   L CB  1 
ATOM   4644 C  CG  . MET   C 1 41  ? 11.353  -55.039 -1.696  1.00 61.36  ? 27  MET   L CG  1 
ATOM   4645 S  SD  . MET   C 1 41  ? 12.673  -54.752 -0.491  1.00 86.41  ? 27  MET   L SD  1 
ATOM   4646 C  CE  . MET   C 1 41  ? 13.250  -56.430 -0.263  1.00 63.00  ? 27  MET   L CE  1 
ATOM   4647 N  N   . ILE   C 1 42  ? 7.576   -54.769 -2.484  1.00 38.41  ? 28  ILE   L N   1 
ATOM   4648 C  CA  . ILE   C 1 42  ? 6.837   -54.501 -3.747  1.00 41.50  ? 28  ILE   L CA  1 
ATOM   4649 C  C   . ILE   C 1 42  ? 5.336   -54.760 -3.512  1.00 46.25  ? 28  ILE   L C   1 
ATOM   4650 O  O   . ILE   C 1 42  ? 4.917   -55.948 -3.469  1.00 40.78  ? 28  ILE   L O   1 
ATOM   4651 C  CB  . ILE   C 1 42  ? 7.412   -55.371 -4.884  1.00 40.87  ? 28  ILE   L CB  1 
ATOM   4652 C  CG1 . ILE   C 1 42  ? 8.925   -55.204 -5.073  1.00 45.04  ? 28  ILE   L CG1 1 
ATOM   4653 C  CG2 . ILE   C 1 42  ? 6.654   -55.092 -6.157  1.00 40.13  ? 28  ILE   L CG2 1 
ATOM   4654 C  CD1 . ILE   C 1 42  ? 9.339   -53.809 -5.591  1.00 47.31  ? 28  ILE   L CD1 1 
ATOM   4655 N  N   . ALA   C 1 43  ? 4.541   -53.700 -3.341  1.00 42.17  ? 29  ALA   L N   1 
ATOM   4656 C  CA  . ALA   C 1 43  ? 3.085   -53.782 -3.059  1.00 40.33  ? 29  ALA   L CA  1 
ATOM   4657 C  C   . ALA   C 1 43  ? 2.404   -54.677 -4.102  1.00 42.95  ? 29  ALA   L C   1 
ATOM   4658 O  O   . ALA   C 1 43  ? 2.679   -54.509 -5.309  1.00 43.28  ? 29  ALA   L O   1 
ATOM   4659 C  CB  . ALA   C 1 43  ? 2.454   -52.407 -3.050  1.00 39.93  ? 29  ALA   L CB  1 
ATOM   4660 N  N   . MET   C 1 44  ? 1.547   -55.596 -3.648  1.00 41.11  ? 30  MET   L N   1 
ATOM   4661 C  CA  . MET   C 1 44  ? 0.678   -56.426 -4.517  1.00 41.17  ? 30  MET   L CA  1 
ATOM   4662 C  C   . MET   C 1 44  ? 1.520   -57.074 -5.603  1.00 37.98  ? 30  MET   L C   1 
ATOM   4663 O  O   . MET   C 1 44  ? 1.114   -57.057 -6.729  1.00 43.94  ? 30  MET   L O   1 
ATOM   4664 C  CB  . MET   C 1 44  ? -0.428  -55.576 -5.146  1.00 44.43  ? 30  MET   L CB  1 
ATOM   4665 C  CG  . MET   C 1 44  ? -1.288  -54.885 -4.098  1.00 45.20  ? 30  MET   L CG  1 
ATOM   4666 S  SD  . MET   C 1 44  ? -2.067  -55.998 -2.842  1.00 47.10  ? 30  MET   L SD  1 
ATOM   4667 C  CE  . MET   C 1 44  ? -2.743  -57.238 -3.963  1.00 45.47  ? 30  MET   L CE  1 
ATOM   4668 N  N   . HIS   C 1 45  ? 2.662   -57.662 -5.252  1.00 40.37  ? 31  HIS   L N   1 
ATOM   4669 C  CA  . HIS   C 1 45  ? 3.622   -58.176 -6.253  1.00 45.11  ? 31  HIS   L CA  1 
ATOM   4670 C  C   . HIS   C 1 45  ? 3.058   -59.421 -6.939  1.00 46.77  ? 31  HIS   L C   1 
ATOM   4671 O  O   . HIS   C 1 45  ? 3.555   -59.726 -8.025  1.00 47.01  ? 31  HIS   L O   1 
ATOM   4672 C  CB  . HIS   C 1 45  ? 4.986   -58.482 -5.636  1.00 46.29  ? 31  HIS   L CB  1 
ATOM   4673 C  CG  . HIS   C 1 45  ? 5.051   -59.791 -4.928  1.00 46.79  ? 31  HIS   L CG  1 
ATOM   4674 N  ND1 . HIS   C 1 45  ? 5.626   -60.936 -5.508  1.00 51.88  ? 31  HIS   L ND1 1 
ATOM   4675 C  CD2 . HIS   C 1 45  ? 4.655   -60.149 -3.687  1.00 48.88  ? 31  HIS   L CD2 1 
ATOM   4676 C  CE1 . HIS   C 1 45  ? 5.542   -61.947 -4.647  1.00 48.30  ? 31  HIS   L CE1 1 
ATOM   4677 N  NE2 . HIS   C 1 45  ? 4.963   -61.487 -3.515  1.00 52.40  ? 31  HIS   L NE2 1 
ATOM   4678 N  N   . ASN   C 1 46  ? 2.089   -60.116 -6.337  1.00 43.76  ? 32  ASN   L N   1 
ATOM   4679 C  CA  . ASN   C 1 46  ? 1.589   -61.405 -6.893  1.00 48.01  ? 32  ASN   L CA  1 
ATOM   4680 C  C   . ASN   C 1 46  ? 0.140   -61.606 -6.446  1.00 43.09  ? 32  ASN   L C   1 
ATOM   4681 O  O   . ASN   C 1 46  ? -0.149  -62.424 -5.554  1.00 43.89  ? 32  ASN   L O   1 
ATOM   4682 C  CB  . ASN   C 1 46  ? 2.517   -62.565 -6.519  1.00 48.55  ? 32  ASN   L CB  1 
ATOM   4683 C  CG  . ASN   C 1 46  ? 2.029   -63.882 -7.080  1.00 51.24  ? 32  ASN   L CG  1 
ATOM   4684 O  OD1 . ASN   C 1 46  ? 1.514   -63.930 -8.183  1.00 48.33  ? 32  ASN   L OD1 1 
ATOM   4685 N  ND2 . ASN   C 1 46  ? 2.120   -64.933 -6.294  1.00 55.73  ? 32  ASN   L ND2 1 
ATOM   4686 N  N   . PRO   C 1 47  ? -0.801  -60.810 -7.020  1.00 44.41  ? 33  PRO   L N   1 
ATOM   4687 C  CA  . PRO   C 1 47  ? -2.181  -60.781 -6.531  1.00 45.28  ? 33  PRO   L CA  1 
ATOM   4688 C  C   . PRO   C 1 47  ? -2.893  -62.123 -6.804  1.00 45.50  ? 33  PRO   L C   1 
ATOM   4689 O  O   . PRO   C 1 47  ? -2.635  -62.738 -7.817  1.00 40.05  ? 33  PRO   L O   1 
ATOM   4690 C  CB  . PRO   C 1 47  ? -2.849  -59.636 -7.316  1.00 45.36  ? 33  PRO   L CB  1 
ATOM   4691 C  CG  . PRO   C 1 47  ? -1.675  -58.850 -7.926  1.00 50.03  ? 33  PRO   L CG  1 
ATOM   4692 C  CD  . PRO   C 1 47  ? -0.604  -59.895 -8.159  1.00 47.69  ? 33  PRO   L CD  1 
ATOM   4693 N  N   . ALA   C 1 48  ? -3.771  -62.520 -5.891  1.00 43.69  ? 34  ALA   L N   1 
ATOM   4694 C  CA  . ALA   C 1 48  ? -4.725  -63.626 -6.048  1.00 43.62  ? 34  ALA   L CA  1 
ATOM   4695 C  C   . ALA   C 1 48  ? -5.571  -63.409 -7.306  1.00 47.06  ? 34  ALA   L C   1 
ATOM   4696 O  O   . ALA   C 1 48  ? -5.900  -62.244 -7.691  1.00 43.18  ? 34  ALA   L O   1 
ATOM   4697 C  CB  . ALA   C 1 48  ? -5.568  -63.754 -4.801  1.00 47.69  ? 34  ALA   L CB  1 
ATOM   4698 N  N   . THR   C 1 49  ? -5.869  -64.518 -7.974  1.00 46.54  ? 35  THR   L N   1 
ATOM   4699 C  CA  . THR   C 1 49  ? -6.722  -64.594 -9.185  1.00 46.36  ? 35  THR   L CA  1 
ATOM   4700 C  C   . THR   C 1 49  ? -7.729  -65.743 -8.980  1.00 45.07  ? 35  THR   L C   1 
ATOM   4701 O  O   . THR   C 1 49  ? -7.598  -66.511 -8.019  1.00 41.52  ? 35  THR   L O   1 
ATOM   4702 C  CB  . THR   C 1 49  ? -5.923  -64.813 -10.476 1.00 50.23  ? 35  THR   L CB  1 
ATOM   4703 O  OG1 . THR   C 1 49  ? -5.215  -66.044 -10.313 1.00 51.76  ? 35  THR   L OG1 1 
ATOM   4704 C  CG2 . THR   C 1 49  ? -4.948  -63.700 -10.801 1.00 47.34  ? 35  THR   L CG2 1 
ATOM   4705 N  N   . ILE   C 1 50  ? -8.751  -65.771 -9.814  1.00 44.83  ? 36  ILE   L N   1 
ATOM   4706 C  CA  . ILE   C 1 50  ? -9.794  -66.834 -9.813  1.00 52.03  ? 36  ILE   L CA  1 
ATOM   4707 C  C   . ILE   C 1 50  ? -9.077  -68.205 -9.930  1.00 52.44  ? 36  ILE   L C   1 
ATOM   4708 O  O   . ILE   C 1 50  ? -9.464  -69.114 -9.181  1.00 53.76  ? 36  ILE   L O   1 
ATOM   4709 C  CB  . ILE   C 1 50  ? -10.828 -66.489 -10.908 1.00 61.26  ? 36  ILE   L CB  1 
ATOM   4710 C  CG1 . ILE   C 1 50  ? -12.162 -67.215 -10.701 1.00 70.73  ? 36  ILE   L CG1 1 
ATOM   4711 C  CG2 . ILE   C 1 50  ? -10.243 -66.703 -12.303 1.00 62.85  ? 36  ILE   L CG2 1 
ATOM   4712 C  CD1 . ILE   C 1 50  ? -13.282 -66.734 -11.615 1.00 73.58  ? 36  ILE   L CD1 1 
ATOM   4713 N  N   . HIS   C 1 51  ? -7.943  -68.307 -10.647 1.00 52.56  ? 37  HIS   L N   1 
ATOM   4714 C  CA  . HIS   C 1 51  ? -7.133  -69.558 -10.772 1.00 55.96  ? 37  HIS   L CA  1 
ATOM   4715 C  C   . HIS   C 1 51  ? -6.171  -69.740 -9.589  1.00 62.01  ? 37  HIS   L C   1 
ATOM   4716 O  O   . HIS   C 1 51  ? -5.808  -70.900 -9.290  1.00 58.47  ? 37  HIS   L O   1 
ATOM   4717 C  CB  . HIS   C 1 51  ? -6.458  -69.617 -12.151 1.00 63.95  ? 37  HIS   L CB  1 
ATOM   4718 C  CG  . HIS   C 1 51  ? -7.460  -69.822 -13.243 1.00 81.05  ? 37  HIS   L CG  1 
ATOM   4719 N  ND1 . HIS   C 1 51  ? -7.873  -68.788 -14.086 1.00 96.16  ? 37  HIS   L ND1 1 
ATOM   4720 C  CD2 . HIS   C 1 51  ? -8.198  -70.902 -13.590 1.00 84.93  ? 37  HIS   L CD2 1 
ATOM   4721 C  CE1 . HIS   C 1 51  ? -8.787  -69.235 -14.926 1.00 83.12  ? 37  HIS   L CE1 1 
ATOM   4722 N  NE2 . HIS   C 1 51  ? -9.006  -70.531 -14.641 1.00 88.40  ? 37  HIS   L NE2 1 
ATOM   4723 N  N   . ASN   C 1 52  ? -5.764  -68.666 -8.910  1.00 56.59  ? 38  ASN   L N   1 
ATOM   4724 C  CA  . ASN   C 1 52  ? -4.817  -68.740 -7.765  1.00 50.43  ? 38  ASN   L CA  1 
ATOM   4725 C  C   . ASN   C 1 52  ? -5.390  -67.917 -6.609  1.00 53.20  ? 38  ASN   L C   1 
ATOM   4726 O  O   . ASN   C 1 52  ? -4.763  -66.950 -6.173  1.00 46.86  ? 38  ASN   L O   1 
ATOM   4727 C  CB  . ASN   C 1 52  ? -3.381  -68.372 -8.185  1.00 51.46  ? 38  ASN   L CB  1 
ATOM   4728 C  CG  . ASN   C 1 52  ? -2.332  -68.680 -7.133  1.00 48.08  ? 38  ASN   L CG  1 
ATOM   4729 O  OD1 . ASN   C 1 52  ? -2.557  -69.496 -6.251  1.00 51.44  ? 38  ASN   L OD1 1 
ATOM   4730 N  ND2 . ASN   C 1 52  ? -1.202  -67.996 -7.175  1.00 50.86  ? 38  ASN   L ND2 1 
ATOM   4731 N  N   . PRO   C 1 53  ? -6.553  -68.337 -6.041  1.00 53.56  ? 39  PRO   L N   1 
ATOM   4732 C  CA  . PRO   C 1 53  ? -7.306  -67.536 -5.069  1.00 54.45  ? 39  PRO   L CA  1 
ATOM   4733 C  C   . PRO   C 1 53  ? -6.599  -67.433 -3.704  1.00 48.95  ? 39  PRO   L C   1 
ATOM   4734 O  O   . PRO   C 1 53  ? -6.930  -66.553 -2.885  1.00 52.01  ? 39  PRO   L O   1 
ATOM   4735 C  CB  . PRO   C 1 53  ? -8.666  -68.277 -4.944  1.00 51.76  ? 39  PRO   L CB  1 
ATOM   4736 C  CG  . PRO   C 1 53  ? -8.330  -69.728 -5.294  1.00 55.93  ? 39  PRO   L CG  1 
ATOM   4737 C  CD  . PRO   C 1 53  ? -7.223  -69.627 -6.330  1.00 57.02  ? 39  PRO   L CD  1 
ATOM   4738 N  N   . ASN   C 1 54  ? -5.669  -68.344 -3.444  1.00 43.80  ? 40  ASN   L N   1 
ATOM   4739 C  CA  . ASN   C 1 54  ? -4.919  -68.368 -2.160  1.00 47.90  ? 40  ASN   L CA  1 
ATOM   4740 C  C   . ASN   C 1 54  ? -3.437  -68.126 -2.457  1.00 49.73  ? 40  ASN   L C   1 
ATOM   4741 O  O   . ASN   C 1 54  ? -2.578  -68.809 -1.870  1.00 45.81  ? 40  ASN   L O   1 
ATOM   4742 C  CB  . ASN   C 1 54  ? -5.160  -69.656 -1.379  1.00 55.76  ? 40  ASN   L CB  1 
ATOM   4743 C  CG  . ASN   C 1 54  ? -6.624  -69.840 -1.042  1.00 53.37  ? 40  ASN   L CG  1 
ATOM   4744 O  OD1 . ASN   C 1 54  ? -7.231  -68.992 -0.396  1.00 55.20  ? 40  ASN   L OD1 1 
ATOM   4745 N  ND2 . ASN   C 1 54  ? -7.202  -70.931 -1.497  1.00 60.94  ? 40  ASN   L ND2 1 
ATOM   4746 N  N   . ALA   C 1 55  ? -3.152  -67.180 -3.350  1.00 46.44  ? 41  ALA   L N   1 
ATOM   4747 C  CA  . ALA   C 1 55  ? -1.775  -66.861 -3.786  1.00 45.86  ? 41  ALA   L CA  1 
ATOM   4748 C  C   . ALA   C 1 55  ? -0.864  -66.721 -2.569  1.00 46.40  ? 41  ALA   L C   1 
ATOM   4749 O  O   . ALA   C 1 55  ? -1.267  -66.145 -1.511  1.00 45.30  ? 41  ALA   L O   1 
ATOM   4750 C  CB  . ALA   C 1 55  ? -1.725  -65.640 -4.667  1.00 45.58  ? 41  ALA   L CB  1 
ATOM   4751 N  N   . GLN   C 1 56  ? 0.336   -67.252 -2.746  1.00 44.48  ? 42  GLN   L N   1 
ATOM   4752 C  CA  . GLN   C 1 56  ? 1.399   -67.296 -1.725  1.00 49.65  ? 42  GLN   L CA  1 
ATOM   4753 C  C   . GLN   C 1 56  ? 2.340   -66.130 -1.968  1.00 42.59  ? 42  GLN   L C   1 
ATOM   4754 O  O   . GLN   C 1 56  ? 2.613   -65.807 -3.145  1.00 47.09  ? 42  GLN   L O   1 
ATOM   4755 C  CB  . GLN   C 1 56  ? 2.163   -68.618 -1.826  1.00 52.82  ? 42  GLN   L CB  1 
ATOM   4756 C  CG  . GLN   C 1 56  ? 1.383   -69.754 -1.209  1.00 61.33  ? 42  GLN   L CG  1 
ATOM   4757 C  CD  . GLN   C 1 56  ? 2.109   -71.059 -1.404  1.00 63.72  ? 42  GLN   L CD  1 
ATOM   4758 O  OE1 . GLN   C 1 56  ? 3.333   -71.136 -1.269  1.00 66.44  ? 42  GLN   L OE1 1 
ATOM   4759 N  NE2 . GLN   C 1 56  ? 1.350   -72.075 -1.767  1.00 59.44  ? 42  GLN   L NE2 1 
ATOM   4760 N  N   . THR   C 1 57  ? 2.835   -65.546 -0.891  1.00 45.21  ? 43  THR   L N   1 
ATOM   4761 C  CA  . THR   C 1 57  ? 3.944   -64.571 -0.971  1.00 45.85  ? 43  THR   L CA  1 
ATOM   4762 C  C   . THR   C 1 57  ? 5.249   -65.359 -0.783  1.00 46.68  ? 43  THR   L C   1 
ATOM   4763 O  O   . THR   C 1 57  ? 5.200   -66.609 -0.731  1.00 46.00  ? 43  THR   L O   1 
ATOM   4764 C  CB  . THR   C 1 57  ? 3.748   -63.420 0.025   1.00 43.72  ? 43  THR   L CB  1 
ATOM   4765 O  OG1 . THR   C 1 57  ? 4.739   -62.434 -0.257  1.00 42.29  ? 43  THR   L OG1 1 
ATOM   4766 C  CG2 . THR   C 1 57  ? 3.862   -63.847 1.469   1.00 43.55  ? 43  THR   L CG2 1 
ATOM   4767 N  N   . GLU   C 1 58  ? 6.356   -64.643 -0.662  1.00 45.75  ? 44  GLU   L N   1 
ATOM   4768 C  CA  . GLU   C 1 58  ? 7.705   -65.213 -0.403  1.00 53.17  ? 44  GLU   L CA  1 
ATOM   4769 C  C   . GLU   C 1 58  ? 8.364   -64.306 0.642   1.00 45.88  ? 44  GLU   L C   1 
ATOM   4770 O  O   . GLU   C 1 58  ? 7.898   -63.167 0.847   1.00 43.01  ? 44  GLU   L O   1 
ATOM   4771 C  CB  . GLU   C 1 58  ? 8.456   -65.387 -1.733  1.00 58.55  ? 44  GLU   L CB  1 
ATOM   4772 C  CG  . GLU   C 1 58  ? 8.264   -64.216 -2.677  1.00 71.39  ? 44  GLU   L CG  1 
ATOM   4773 C  CD  . GLU   C 1 58  ? 9.159   -64.124 -3.906  1.00 86.36  ? 44  GLU   L CD  1 
ATOM   4774 O  OE1 . GLU   C 1 58  ? 10.390  -64.343 -3.780  1.00 87.12  ? 44  GLU   L OE1 1 
ATOM   4775 O  OE2 . GLU   C 1 58  ? 8.628   -63.767 -4.984  1.00 95.42  ? 44  GLU   L OE2 1 
ATOM   4776 N  N   . PHE   C 1 59  ? 9.336   -64.854 1.350   1.00 40.25  ? 45  PHE   L N   1 
ATOM   4777 C  CA  . PHE   C 1 59  ? 10.062  -64.238 2.478   1.00 43.11  ? 45  PHE   L CA  1 
ATOM   4778 C  C   . PHE   C 1 59  ? 11.461  -63.959 1.934   1.00 50.57  ? 45  PHE   L C   1 
ATOM   4779 O  O   . PHE   C 1 59  ? 12.233  -64.923 1.799   1.00 50.16  ? 45  PHE   L O   1 
ATOM   4780 C  CB  . PHE   C 1 59  ? 9.985   -65.217 3.647   1.00 42.95  ? 45  PHE   L CB  1 
ATOM   4781 C  CG  . PHE   C 1 59  ? 10.146  -64.649 5.028   1.00 44.94  ? 45  PHE   L CG  1 
ATOM   4782 C  CD1 . PHE   C 1 59  ? 9.308   -63.644 5.477   1.00 42.72  ? 45  PHE   L CD1 1 
ATOM   4783 C  CD2 . PHE   C 1 59  ? 11.111  -65.152 5.895   1.00 46.84  ? 45  PHE   L CD2 1 
ATOM   4784 C  CE1 . PHE   C 1 59  ? 9.442   -63.144 6.763   1.00 46.52  ? 45  PHE   L CE1 1 
ATOM   4785 C  CE2 . PHE   C 1 59  ? 11.240  -64.650 7.182   1.00 49.05  ? 45  PHE   L CE2 1 
ATOM   4786 C  CZ  . PHE   C 1 59  ? 10.410  -63.638 7.610   1.00 49.68  ? 45  PHE   L CZ  1 
ATOM   4787 N  N   . VAL   C 1 60  ? 11.714  -62.727 1.498   1.00 44.27  ? 46  VAL   L N   1 
ATOM   4788 C  CA  . VAL   C 1 60  ? 12.909  -62.345 0.690   1.00 42.36  ? 46  VAL   L CA  1 
ATOM   4789 C  C   . VAL   C 1 60  ? 13.978  -61.764 1.599   1.00 41.49  ? 46  VAL   L C   1 
ATOM   4790 O  O   . VAL   C 1 60  ? 13.639  -61.117 2.596   1.00 42.75  ? 46  VAL   L O   1 
ATOM   4791 C  CB  . VAL   C 1 60  ? 12.581  -61.346 -0.435  1.00 49.16  ? 46  VAL   L CB  1 
ATOM   4792 C  CG1 . VAL   C 1 60  ? 11.700  -61.968 -1.492  1.00 53.65  ? 46  VAL   L CG1 1 
ATOM   4793 C  CG2 . VAL   C 1 60  ? 11.950  -60.061 0.090   1.00 51.34  ? 46  VAL   L CG2 1 
ATOM   4794 N  N   . GLU   C 1 61  ? 15.236  -61.988 1.226   1.00 41.43  ? 47  GLU   L N   1 
ATOM   4795 C  CA  . GLU   C 1 61  ? 16.432  -61.636 2.027   1.00 43.61  ? 47  GLU   L CA  1 
ATOM   4796 C  C   . GLU   C 1 61  ? 17.077  -60.394 1.413   1.00 37.73  ? 47  GLU   L C   1 
ATOM   4797 O  O   . GLU   C 1 61  ? 17.134  -60.283 0.199   1.00 39.23  ? 47  GLU   L O   1 
ATOM   4798 C  CB  . GLU   C 1 61  ? 17.448  -62.788 2.049   1.00 43.84  ? 47  GLU   L CB  1 
ATOM   4799 C  CG  . GLU   C 1 61  ? 18.513  -62.556 3.099   1.00 50.71  ? 47  GLU   L CG  1 
ATOM   4800 C  CD  . GLU   C 1 61  ? 19.596  -63.616 3.227   1.00 55.69  ? 47  GLU   L CD  1 
ATOM   4801 O  OE1 . GLU   C 1 61  ? 20.368  -63.807 2.273   1.00 58.99  ? 47  GLU   L OE1 1 
ATOM   4802 O  OE2 . GLU   C 1 61  ? 19.696  -64.171 4.303   1.00 53.45  ? 47  GLU   L OE2 1 
ATOM   4803 N  N   . PHE   C 1 62  ? 17.613  -59.501 2.221   1.00 37.76  ? 48  PHE   L N   1 
ATOM   4804 C  CA  . PHE   C 1 62  ? 18.192  -58.257 1.678   1.00 38.06  ? 48  PHE   L CA  1 
ATOM   4805 C  C   . PHE   C 1 62  ? 19.238  -57.719 2.648   1.00 37.00  ? 48  PHE   L C   1 
ATOM   4806 O  O   . PHE   C 1 62  ? 19.212  -57.975 3.853   1.00 41.65  ? 48  PHE   L O   1 
ATOM   4807 C  CB  . PHE   C 1 62  ? 17.041  -57.290 1.328   1.00 38.39  ? 48  PHE   L CB  1 
ATOM   4808 C  CG  . PHE   C 1 62  ? 16.195  -56.873 2.496   1.00 37.23  ? 48  PHE   L CG  1 
ATOM   4809 C  CD1 . PHE   C 1 62  ? 16.592  -55.849 3.332   1.00 36.72  ? 48  PHE   L CD1 1 
ATOM   4810 C  CD2 . PHE   C 1 62  ? 15.015  -57.547 2.783   1.00 40.59  ? 48  PHE   L CD2 1 
ATOM   4811 C  CE1 . PHE   C 1 62  ? 15.806  -55.470 4.413   1.00 41.32  ? 48  PHE   L CE1 1 
ATOM   4812 C  CE2 . PHE   C 1 62  ? 14.244  -57.188 3.877   1.00 43.39  ? 48  PHE   L CE2 1 
ATOM   4813 C  CZ  . PHE   C 1 62  ? 14.640  -56.154 4.695   1.00 40.68  ? 48  PHE   L CZ  1 
ATOM   4814 N  N   . PRO   C 1 63  ? 20.217  -56.968 2.127   1.00 36.82  ? 49  PRO   L N   1 
ATOM   4815 C  CA  . PRO   C 1 63  ? 21.257  -56.378 2.941   1.00 36.39  ? 49  PRO   L CA  1 
ATOM   4816 C  C   . PRO   C 1 63  ? 20.823  -55.150 3.751   1.00 38.13  ? 49  PRO   L C   1 
ATOM   4817 O  O   . PRO   C 1 63  ? 20.037  -54.361 3.303   1.00 38.94  ? 49  PRO   L O   1 
ATOM   4818 C  CB  . PRO   C 1 63  ? 22.303  -55.890 1.926   1.00 36.59  ? 49  PRO   L CB  1 
ATOM   4819 C  CG  . PRO   C 1 63  ? 21.517  -55.657 0.675   1.00 40.51  ? 49  PRO   L CG  1 
ATOM   4820 C  CD  . PRO   C 1 63  ? 20.379  -56.667 0.691   1.00 40.86  ? 49  PRO   L CD  1 
ATOM   4821 N  N   . ILE   C 1 64  ? 21.378  -55.051 4.944   1.00 35.99  ? 50  ILE   L N   1 
ATOM   4822 C  CA  . ILE   C 1 64  ? 21.426  -53.818 5.761   1.00 36.97  ? 50  ILE   L CA  1 
ATOM   4823 C  C   . ILE   C 1 64  ? 22.854  -53.323 5.631   1.00 39.51  ? 50  ILE   L C   1 
ATOM   4824 O  O   . ILE   C 1 64  ? 23.788  -54.141 5.906   1.00 38.21  ? 50  ILE   L O   1 
ATOM   4825 C  CB  . ILE   C 1 64  ? 21.045  -54.108 7.221   1.00 37.81  ? 50  ILE   L CB  1 
ATOM   4826 C  CG1 . ILE   C 1 64  ? 19.789  -54.981 7.337   1.00 40.42  ? 50  ILE   L CG1 1 
ATOM   4827 C  CG2 . ILE   C 1 64  ? 20.940  -52.817 8.011   1.00 40.80  ? 50  ILE   L CG2 1 
ATOM   4828 C  CD1 . ILE   C 1 64  ? 18.549  -54.395 6.747   1.00 41.93  ? 50  ILE   L CD1 1 
ATOM   4829 N  N   . TYR   C 1 65  ? 23.038  -52.061 5.252   1.00 32.78  ? 51  TYR   L N   1 
ATOM   4830 C  CA  . TYR   C 1 65  ? 24.390  -51.476 5.147   1.00 34.03  ? 51  TYR   L CA  1 
ATOM   4831 C  C   . TYR   C 1 65  ? 24.401  -50.010 5.544   1.00 36.80  ? 51  TYR   L C   1 
ATOM   4832 O  O   . TYR   C 1 65  ? 23.332  -49.389 5.645   1.00 34.68  ? 51  TYR   L O   1 
ATOM   4833 C  CB  . TYR   C 1 65  ? 24.936  -51.671 3.736   1.00 35.14  ? 51  TYR   L CB  1 
ATOM   4834 C  CG  . TYR   C 1 65  ? 24.394  -50.790 2.641   1.00 34.11  ? 51  TYR   L CG  1 
ATOM   4835 C  CD1 . TYR   C 1 65  ? 23.245  -51.131 1.946   1.00 38.43  ? 51  TYR   L CD1 1 
ATOM   4836 C  CD2 . TYR   C 1 65  ? 25.114  -49.699 2.197   1.00 38.36  ? 51  TYR   L CD2 1 
ATOM   4837 C  CE1 . TYR   C 1 65  ? 22.783  -50.348 0.896   1.00 37.36  ? 51  TYR   L CE1 1 
ATOM   4838 C  CE2 . TYR   C 1 65  ? 24.673  -48.898 1.152   1.00 40.23  ? 51  TYR   L CE2 1 
ATOM   4839 C  CZ  . TYR   C 1 65  ? 23.509  -49.236 0.483   1.00 37.31  ? 51  TYR   L CZ  1 
ATOM   4840 O  OH  . TYR   C 1 65  ? 23.093  -48.426 -0.548  1.00 36.45  ? 51  TYR   L OH  1 
ATOM   4841 N  N   . THR   C 1 66  ? 25.614  -49.512 5.724   1.00 33.35  ? 52  THR   L N   1 
ATOM   4842 C  CA  . THR   C 1 66  ? 25.945  -48.143 6.131   1.00 33.46  ? 52  THR   L CA  1 
ATOM   4843 C  C   . THR   C 1 66  ? 27.120  -47.664 5.284   1.00 36.14  ? 52  THR   L C   1 
ATOM   4844 O  O   . THR   C 1 66  ? 27.876  -48.504 4.706   1.00 33.09  ? 52  THR   L O   1 
ATOM   4845 C  CB  . THR   C 1 66  ? 26.260  -48.066 7.629   1.00 39.79  ? 52  THR   L CB  1 
ATOM   4846 O  OG1 . THR   C 1 66  ? 27.306  -48.982 7.904   1.00 39.23  ? 52  THR   L OG1 1 
ATOM   4847 C  CG2 . THR   C 1 66  ? 25.071  -48.399 8.512   1.00 39.46  ? 52  THR   L CG2 1 
ATOM   4848 N  N   . VAL   C 1 67  ? 27.266  -46.350 5.186   1.00 35.56  ? 53  VAL   L N   1 
ATOM   4849 C  CA  . VAL   C 1 67  ? 28.345  -45.735 4.376   1.00 34.38  ? 53  VAL   L CA  1 
ATOM   4850 C  C   . VAL   C 1 67  ? 29.118  -44.794 5.272   1.00 36.44  ? 53  VAL   L C   1 
ATOM   4851 O  O   . VAL   C 1 67  ? 28.483  -43.927 5.904   1.00 38.21  ? 53  VAL   L O   1 
ATOM   4852 C  CB  . VAL   C 1 67  ? 27.777  -45.036 3.126   1.00 35.13  ? 53  VAL   L CB  1 
ATOM   4853 C  CG1 . VAL   C 1 67  ? 28.840  -44.261 2.373   1.00 34.91  ? 53  VAL   L CG1 1 
ATOM   4854 C  CG2 . VAL   C 1 67  ? 27.092  -46.039 2.218   1.00 36.91  ? 53  VAL   L CG2 1 
ATOM   4855 N  N   . LEU   C 1 68  ? 30.445  -44.925 5.287   1.00 34.09  ? 54  LEU   L N   1 
ATOM   4856 C  CA  . LEU   C 1 68  ? 31.353  -43.976 5.981   1.00 33.44  ? 54  LEU   L CA  1 
ATOM   4857 C  C   . LEU   C 1 68  ? 32.060  -43.149 4.925   1.00 36.37  ? 54  LEU   L C   1 
ATOM   4858 O  O   . LEU   C 1 68  ? 32.683  -43.741 4.023   1.00 35.41  ? 54  LEU   L O   1 
ATOM   4859 C  CB  . LEU   C 1 68  ? 32.374  -44.748 6.832   1.00 35.94  ? 54  LEU   L CB  1 
ATOM   4860 C  CG  . LEU   C 1 68  ? 33.485  -43.892 7.458   1.00 38.11  ? 54  LEU   L CG  1 
ATOM   4861 C  CD1 . LEU   C 1 68  ? 32.897  -43.088 8.612   1.00 39.99  ? 54  LEU   L CD1 1 
ATOM   4862 C  CD2 . LEU   C 1 68  ? 34.624  -44.787 7.991   1.00 40.50  ? 54  LEU   L CD2 1 
ATOM   4863 N  N   . ILE   C 1 69  ? 32.017  -41.826 5.063   1.00 34.49  ? 55  ILE   L N   1 
ATOM   4864 C  CA  . ILE   C 1 69  ? 32.837  -40.915 4.245   1.00 38.36  ? 55  ILE   L CA  1 
ATOM   4865 C  C   . ILE   C 1 69  ? 33.965  -40.414 5.136   1.00 41.69  ? 55  ILE   L C   1 
ATOM   4866 O  O   . ILE   C 1 69  ? 33.718  -39.613 6.057   1.00 37.56  ? 55  ILE   L O   1 
ATOM   4867 C  CB  . ILE   C 1 69  ? 31.991  -39.790 3.614   1.00 41.32  ? 55  ILE   L CB  1 
ATOM   4868 C  CG1 . ILE   C 1 69  ? 30.838  -40.343 2.761   1.00 46.98  ? 55  ILE   L CG1 1 
ATOM   4869 C  CG2 . ILE   C 1 69  ? 32.859  -38.873 2.789   1.00 40.49  ? 55  ILE   L CG2 1 
ATOM   4870 C  CD1 . ILE   C 1 69  ? 29.578  -40.652 3.513   1.00 55.92  ? 55  ILE   L CD1 1 
ATOM   4871 N  N   . ASP   C 1 70  ? 35.170  -40.930 4.912   1.00 40.98  ? 56  ASP   L N   1 
ATOM   4872 C  CA  . ASP   C 1 70  ? 36.398  -40.436 5.589   1.00 40.53  ? 56  ASP   L CA  1 
ATOM   4873 C  C   . ASP   C 1 70  ? 36.847  -39.177 4.851   1.00 39.12  ? 56  ASP   L C   1 
ATOM   4874 O  O   . ASP   C 1 70  ? 37.500  -39.272 3.829   1.00 39.27  ? 56  ASP   L O   1 
ATOM   4875 C  CB  . ASP   C 1 70  ? 37.456  -41.532 5.686   1.00 43.65  ? 56  ASP   L CB  1 
ATOM   4876 C  CG  . ASP   C 1 70  ? 38.643  -41.131 6.539   1.00 45.68  ? 56  ASP   L CG  1 
ATOM   4877 O  OD1 . ASP   C 1 70  ? 38.606  -40.040 7.140   1.00 47.17  ? 56  ASP   L OD1 1 
ATOM   4878 O  OD2 . ASP   C 1 70  ? 39.594  -41.907 6.571   1.00 50.52  ? 56  ASP   L OD2 1 
ATOM   4879 N  N   . HIS   C 1 71  ? 36.397  -38.027 5.323   1.00 38.67  ? 57  HIS   L N   1 
ATOM   4880 C  CA  . HIS   C 1 71  ? 36.587  -36.717 4.660   1.00 41.86  ? 57  HIS   L CA  1 
ATOM   4881 C  C   . HIS   C 1 71  ? 37.614  -35.936 5.461   1.00 37.22  ? 57  HIS   L C   1 
ATOM   4882 O  O   . HIS   C 1 71  ? 37.568  -35.978 6.681   1.00 41.69  ? 57  HIS   L O   1 
ATOM   4883 C  CB  . HIS   C 1 71  ? 35.251  -35.961 4.625   1.00 37.56  ? 57  HIS   L CB  1 
ATOM   4884 C  CG  . HIS   C 1 71  ? 35.189  -34.890 3.606   1.00 41.90  ? 57  HIS   L CG  1 
ATOM   4885 N  ND1 . HIS   C 1 71  ? 35.886  -33.701 3.740   1.00 40.68  ? 57  HIS   L ND1 1 
ATOM   4886 C  CD2 . HIS   C 1 71  ? 34.545  -34.845 2.414   1.00 42.22  ? 57  HIS   L CD2 1 
ATOM   4887 C  CE1 . HIS   C 1 71  ? 35.664  -32.955 2.679   1.00 38.66  ? 57  HIS   L CE1 1 
ATOM   4888 N  NE2 . HIS   C 1 71  ? 34.857  -33.646 1.835   1.00 38.02  ? 57  HIS   L NE2 1 
ATOM   4889 N  N   . PRO   C 1 72  ? 38.511  -35.154 4.836   1.00 42.14  ? 58  PRO   L N   1 
ATOM   4890 C  CA  . PRO   C 1 72  ? 39.426  -34.305 5.605   1.00 43.33  ? 58  PRO   L CA  1 
ATOM   4891 C  C   . PRO   C 1 72  ? 38.738  -33.302 6.535   1.00 48.38  ? 58  PRO   L C   1 
ATOM   4892 O  O   . PRO   C 1 72  ? 39.340  -32.933 7.528   1.00 44.17  ? 58  PRO   L O   1 
ATOM   4893 C  CB  . PRO   C 1 72  ? 40.243  -33.545 4.550   1.00 47.15  ? 58  PRO   L CB  1 
ATOM   4894 C  CG  . PRO   C 1 72  ? 39.607  -33.861 3.204   1.00 49.12  ? 58  PRO   L CG  1 
ATOM   4895 C  CD  . PRO   C 1 72  ? 38.734  -35.084 3.381   1.00 45.16  ? 58  PRO   L CD  1 
ATOM   4896 N  N   . GLU   C 1 73  ? 37.504  -32.878 6.218   1.00 41.05  ? 59  GLU   L N   1 
ATOM   4897 C  CA  . GLU   C 1 73  ? 36.774  -31.906 7.071   1.00 43.69  ? 59  GLU   L CA  1 
ATOM   4898 C  C   . GLU   C 1 73  ? 36.104  -32.638 8.230   1.00 43.86  ? 59  GLU   L C   1 
ATOM   4899 O  O   . GLU   C 1 73  ? 35.581  -31.948 9.081   1.00 49.52  ? 59  GLU   L O   1 
ATOM   4900 C  CB  . GLU   C 1 73  ? 35.760  -31.084 6.270   1.00 45.19  ? 59  GLU   L CB  1 
ATOM   4901 C  CG  . GLU   C 1 73  ? 36.369  -30.350 5.091   1.00 47.58  ? 59  GLU   L CG  1 
ATOM   4902 C  CD  . GLU   C 1 73  ? 35.343  -29.580 4.279   1.00 48.66  ? 59  GLU   L CD  1 
ATOM   4903 O  OE1 . GLU   C 1 73  ? 34.497  -28.954 4.899   1.00 49.96  ? 59  GLU   L OE1 1 
ATOM   4904 O  OE2 . GLU   C 1 73  ? 35.393  -29.608 3.020   1.00 47.31  ? 59  GLU   L OE2 1 
ATOM   4905 N  N   . GLY   C 1 74  ? 36.120  -33.970 8.266   1.00 39.41  ? 60  GLY   L N   1 
ATOM   4906 C  CA  . GLY   C 1 74  ? 35.533  -34.762 9.359   1.00 41.88  ? 60  GLY   L CA  1 
ATOM   4907 C  C   . GLY   C 1 74  ? 34.759  -35.956 8.821   1.00 42.31  ? 60  GLY   L C   1 
ATOM   4908 O  O   . GLY   C 1 74  ? 34.279  -35.898 7.691   1.00 48.46  ? 60  GLY   L O   1 
ATOM   4909 N  N   . LYS   C 1 75  ? 34.749  -37.045 9.570   1.00 38.29  ? 61  LYS   L N   1 
ATOM   4910 C  CA  . LYS   C 1 75  ? 34.104  -38.317 9.201   1.00 36.61  ? 61  LYS   L CA  1 
ATOM   4911 C  C   . LYS   C 1 75  ? 32.579  -38.146 9.256   1.00 39.72  ? 61  LYS   L C   1 
ATOM   4912 O  O   . LYS   C 1 75  ? 32.060  -37.564 10.244  1.00 41.80  ? 61  LYS   L O   1 
ATOM   4913 C  CB  . LYS   C 1 75  ? 34.641  -39.391 10.132  1.00 41.27  ? 61  LYS   L CB  1 
ATOM   4914 C  CG  . LYS   C 1 75  ? 36.112  -39.716 9.869   1.00 43.96  ? 61  LYS   L CG  1 
ATOM   4915 C  CD  . LYS   C 1 75  ? 36.696  -40.786 10.760  1.00 49.11  ? 61  LYS   L CD  1 
ATOM   4916 C  CE  . LYS   C 1 75  ? 38.125  -41.192 10.412  1.00 49.99  ? 61  LYS   L CE  1 
ATOM   4917 N  NZ  . LYS   C 1 75  ? 39.020  -40.038 10.148  1.00 49.87  ? 61  LYS   L NZ  1 
ATOM   4918 N  N   . ILE   C 1 76  ? 31.921  -38.574 8.194   1.00 38.26  ? 62  ILE   L N   1 
ATOM   4919 C  CA  . ILE   C 1 76  ? 30.444  -38.543 8.023   1.00 38.70  ? 62  ILE   L CA  1 
ATOM   4920 C  C   . ILE   C 1 76  ? 29.968  -39.998 7.865   1.00 38.53  ? 62  ILE   L C   1 
ATOM   4921 O  O   . ILE   C 1 76  ? 30.480  -40.755 6.992   1.00 38.89  ? 62  ILE   L O   1 
ATOM   4922 C  CB  . ILE   C 1 76  ? 30.058  -37.680 6.796   1.00 39.01  ? 62  ILE   L CB  1 
ATOM   4923 C  CG1 . ILE   C 1 76  ? 30.572  -36.240 6.905   1.00 38.11  ? 62  ILE   L CG1 1 
ATOM   4924 C  CG2 . ILE   C 1 76  ? 28.555  -37.701 6.579   1.00 40.08  ? 62  ILE   L CG2 1 
ATOM   4925 C  CD1 . ILE   C 1 76  ? 30.693  -35.592 5.586   1.00 38.96  ? 62  ILE   L CD1 1 
ATOM   4926 N  N   . LEU   C 1 77  ? 28.983  -40.373 8.667   1.00 33.81  ? 63  LEU   L N   1 
ATOM   4927 C  CA  . LEU   C 1 77  ? 28.347  -41.691 8.585   1.00 34.92  ? 63  LEU   L CA  1 
ATOM   4928 C  C   . LEU   C 1 77  ? 26.918  -41.530 8.050   1.00 36.25  ? 63  LEU   L C   1 
ATOM   4929 O  O   . LEU   C 1 77  ? 26.184  -40.733 8.610   1.00 35.91  ? 63  LEU   L O   1 
ATOM   4930 C  CB  . LEU   C 1 77  ? 28.358  -42.272 9.999   1.00 35.79  ? 63  LEU   L CB  1 
ATOM   4931 C  CG  . LEU   C 1 77  ? 27.796  -43.677 10.130  1.00 38.81  ? 63  LEU   L CG  1 
ATOM   4932 C  CD1 . LEU   C 1 77  ? 28.541  -44.653 9.229   1.00 43.88  ? 63  LEU   L CD1 1 
ATOM   4933 C  CD2 . LEU   C 1 77  ? 27.867  -44.123 11.573  1.00 43.89  ? 63  LEU   L CD2 1 
ATOM   4934 N  N   . PHE   C 1 78  ? 26.519  -42.344 7.091   1.00 34.05  ? 64  PHE   L N   1 
ATOM   4935 C  CA  . PHE   C 1 78  ? 25.134  -42.384 6.563   1.00 33.88  ? 64  PHE   L CA  1 
ATOM   4936 C  C   . PHE   C 1 78  ? 24.482  -43.671 7.051   1.00 36.37  ? 64  PHE   L C   1 
ATOM   4937 O  O   . PHE   C 1 78  ? 24.971  -44.784 6.699   1.00 32.93  ? 64  PHE   L O   1 
ATOM   4938 C  CB  . PHE   C 1 78  ? 25.151  -42.208 5.037   1.00 37.96  ? 64  PHE   L CB  1 
ATOM   4939 C  CG  . PHE   C 1 78  ? 23.787  -42.152 4.411   1.00 31.68  ? 64  PHE   L CG  1 
ATOM   4940 C  CD1 . PHE   C 1 78  ? 23.073  -40.969 4.383   1.00 34.40  ? 64  PHE   L CD1 1 
ATOM   4941 C  CD2 . PHE   C 1 78  ? 23.190  -43.294 3.908   1.00 33.65  ? 64  PHE   L CD2 1 
ATOM   4942 C  CE1 . PHE   C 1 78  ? 21.806  -40.903 3.820   1.00 35.25  ? 64  PHE   L CE1 1 
ATOM   4943 C  CE2 . PHE   C 1 78  ? 21.928  -43.237 3.329   1.00 34.37  ? 64  PHE   L CE2 1 
ATOM   4944 C  CZ  . PHE   C 1 78  ? 21.232  -42.025 3.278   1.00 33.87  ? 64  PHE   L CZ  1 
ATOM   4945 N  N   . ASP   C 1 79  ? 23.466  -43.527 7.908   1.00 32.93  ? 65  ASP   L N   1 
ATOM   4946 C  CA  . ASP   C 1 79  ? 22.687  -44.643 8.519   1.00 35.77  ? 65  ASP   L CA  1 
ATOM   4947 C  C   . ASP   C 1 79  ? 23.582  -45.374 9.541   1.00 34.64  ? 65  ASP   L C   1 
ATOM   4948 O  O   . ASP   C 1 79  ? 24.790  -45.066 9.589   1.00 34.48  ? 65  ASP   L O   1 
ATOM   4949 C  CB  . ASP   C 1 79  ? 22.061  -45.609 7.496   1.00 38.34  ? 65  ASP   L CB  1 
ATOM   4950 C  CG  . ASP   C 1 79  ? 20.765  -45.110 6.847   1.00 47.18  ? 65  ASP   L CG  1 
ATOM   4951 O  OD1 . ASP   C 1 79  ? 20.212  -44.094 7.362   1.00 38.98  ? 65  ASP   L OD1 1 
ATOM   4952 O  OD2 . ASP   C 1 79  ? 20.339  -45.693 5.785   1.00 41.01  ? 65  ASP   L OD2 1 
ATOM   4953 N  N   . THR   C 1 80  ? 22.990  -46.247 10.361  1.00 36.08  ? 66  THR   L N   1 
ATOM   4954 C  CA  . THR   C 1 80  ? 23.694  -46.879 11.501  1.00 34.58  ? 66  THR   L CA  1 
ATOM   4955 C  C   . THR   C 1 80  ? 23.266  -48.331 11.685  1.00 34.70  ? 66  THR   L C   1 
ATOM   4956 O  O   . THR   C 1 80  ? 23.662  -48.893 12.713  1.00 39.68  ? 66  THR   L O   1 
ATOM   4957 C  CB  . THR   C 1 80  ? 23.515  -46.084 12.801  1.00 36.08  ? 66  THR   L CB  1 
ATOM   4958 O  OG1 . THR   C 1 80  ? 22.183  -46.273 13.276  1.00 35.61  ? 66  THR   L OG1 1 
ATOM   4959 C  CG2 . THR   C 1 80  ? 23.812  -44.615 12.652  1.00 36.02  ? 66  THR   L CG2 1 
ATOM   4960 N  N   . SER   C 1 81  ? 22.457  -48.894 10.782  1.00 33.57  ? 67  SER   L N   1 
ATOM   4961 C  CA  . SER   C 1 81  ? 22.020  -50.306 10.819  1.00 34.59  ? 67  SER   L CA  1 
ATOM   4962 C  C   . SER   C 1 81  ? 21.219  -50.589 12.110  1.00 38.73  ? 67  SER   L C   1 
ATOM   4963 O  O   . SER   C 1 81  ? 20.448  -49.679 12.567  1.00 40.43  ? 67  SER   L O   1 
ATOM   4964 C  CB  . SER   C 1 81  ? 23.225  -51.282 10.597  1.00 37.61  ? 67  SER   L CB  1 
ATOM   4965 O  OG  . SER   C 1 81  ? 24.088  -51.293 11.716  1.00 36.67  ? 67  SER   L OG  1 
ATOM   4966 N  N   . CYS   C 1 82  ? 21.207  -51.846 12.553  1.00 36.82  ? 68  CYS   L N   1 
ATOM   4967 C  CA  . CYS   C 1 82  ? 20.387  -52.349 13.687  1.00 36.68  ? 68  CYS   L CA  1 
ATOM   4968 C  C   . CYS   C 1 82  ? 21.226  -52.386 14.967  1.00 38.10  ? 68  CYS   L C   1 
ATOM   4969 O  O   . CYS   C 1 82  ? 22.471  -52.553 14.907  1.00 39.01  ? 68  CYS   L O   1 
ATOM   4970 C  CB  . CYS   C 1 82  ? 19.837  -53.742 13.427  1.00 39.63  ? 68  CYS   L CB  1 
ATOM   4971 S  SG  . CYS   C 1 82  ? 19.058  -53.946 11.810  1.00 38.95  ? 68  CYS   L SG  1 
ATOM   4972 N  N   . ASN   C 1 83  ? 20.584  -52.266 16.119  1.00 34.29  ? 69  ASN   L N   1 
ATOM   4973 C  CA  . ASN   C 1 83  ? 21.346  -52.359 17.386  1.00 39.36  ? 69  ASN   L CA  1 
ATOM   4974 C  C   . ASN   C 1 83  ? 21.796  -53.822 17.569  1.00 35.87  ? 69  ASN   L C   1 
ATOM   4975 O  O   . ASN   C 1 83  ? 21.046  -54.744 17.296  1.00 34.13  ? 69  ASN   L O   1 
ATOM   4976 C  CB  . ASN   C 1 83  ? 20.529  -51.819 18.566  1.00 38.12  ? 69  ASN   L CB  1 
ATOM   4977 C  CG  . ASN   C 1 83  ? 21.417  -51.563 19.760  1.00 41.04  ? 69  ASN   L CG  1 
ATOM   4978 O  OD1 . ASN   C 1 83  ? 22.019  -50.485 19.923  1.00 41.84  ? 69  ASN   L OD1 1 
ATOM   4979 N  ND2 . ASN   C 1 83  ? 21.511  -52.578 20.588  1.00 39.78  ? 69  ASN   L ND2 1 
ATOM   4980 N  N   . PRO   C 1 84  ? 23.028  -54.094 18.030  1.00 41.60  ? 70  PRO   L N   1 
ATOM   4981 C  CA  . PRO   C 1 84  ? 23.443  -55.483 18.316  1.00 46.23  ? 70  PRO   L CA  1 
ATOM   4982 C  C   . PRO   C 1 84  ? 22.506  -56.223 19.286  1.00 46.18  ? 70  PRO   L C   1 
ATOM   4983 O  O   . PRO   C 1 84  ? 22.411  -57.433 19.252  1.00 44.99  ? 70  PRO   L O   1 
ATOM   4984 C  CB  . PRO   C 1 84  ? 24.832  -55.333 18.961  1.00 44.03  ? 70  PRO   L CB  1 
ATOM   4985 C  CG  . PRO   C 1 84  ? 25.336  -53.972 18.476  1.00 46.83  ? 70  PRO   L CG  1 
ATOM   4986 C  CD  . PRO   C 1 84  ? 24.082  -53.105 18.324  1.00 40.26  ? 70  PRO   L CD  1 
ATOM   4987 N  N   . ASN   C 1 85  ? 21.751  -55.492 20.107  1.00 43.24  ? 71  ASN   L N   1 
ATOM   4988 C  CA  . ASN   C 1 85  ? 20.812  -56.110 21.081  1.00 42.32  ? 71  ASN   L CA  1 
ATOM   4989 C  C   . ASN   C 1 85  ? 19.390  -56.179 20.531  1.00 42.11  ? 71  ASN   L C   1 
ATOM   4990 O  O   . ASN   C 1 85  ? 18.468  -56.213 21.359  1.00 42.23  ? 71  ASN   L O   1 
ATOM   4991 C  CB  . ASN   C 1 85  ? 20.743  -55.326 22.393  1.00 52.92  ? 71  ASN   L CB  1 
ATOM   4992 C  CG  . ASN   C 1 85  ? 22.112  -55.039 22.954  1.00 57.62  ? 71  ASN   L CG  1 
ATOM   4993 O  OD1 . ASN   C 1 85  ? 22.596  -53.896 22.922  1.00 69.96  ? 71  ASN   L OD1 1 
ATOM   4994 N  ND2 . ASN   C 1 85  ? 22.757  -56.100 23.403  1.00 60.68  ? 71  ASN   L ND2 1 
ATOM   4995 N  N   . SER   C 1 86  ? 19.193  -56.183 19.210  1.00 40.04  ? 72  SER   L N   1 
ATOM   4996 C  CA  . SER   C 1 86  ? 17.826  -56.134 18.627  1.00 40.06  ? 72  SER   L CA  1 
ATOM   4997 C  C   . SER   C 1 86  ? 17.111  -57.472 18.857  1.00 43.17  ? 72  SER   L C   1 
ATOM   4998 O  O   . SER   C 1 86  ? 15.931  -57.474 19.284  1.00 40.69  ? 72  SER   L O   1 
ATOM   4999 C  CB  . SER   C 1 86  ? 17.859  -55.769 17.169  1.00 37.14  ? 72  SER   L CB  1 
ATOM   5000 O  OG  . SER   C 1 86  ? 18.455  -54.490 16.996  1.00 41.26  ? 72  SER   L OG  1 
ATOM   5001 N  N   . MET   C 1 87  ? 17.793  -58.564 18.538  1.00 40.03  ? 73  MET   L N   1 
ATOM   5002 C  CA  . MET   C 1 87  ? 17.143  -59.875 18.306  1.00 41.03  ? 73  MET   L CA  1 
ATOM   5003 C  C   . MET   C 1 87  ? 17.281  -60.722 19.583  1.00 43.68  ? 73  MET   L C   1 
ATOM   5004 O  O   . MET   C 1 87  ? 18.154  -60.427 20.396  1.00 40.38  ? 73  MET   L O   1 
ATOM   5005 C  CB  . MET   C 1 87  ? 17.793  -60.619 17.126  1.00 46.43  ? 73  MET   L CB  1 
ATOM   5006 C  CG  . MET   C 1 87  ? 17.512  -59.994 15.743  1.00 45.46  ? 73  MET   L CG  1 
ATOM   5007 S  SD  . MET   C 1 87  ? 15.809  -60.138 15.184  1.00 43.09  ? 73  MET   L SD  1 
ATOM   5008 C  CE  . MET   C 1 87  ? 15.579  -61.915 14.975  1.00 50.05  ? 73  MET   L CE  1 
ATOM   5009 N  N   . GLY   C 1 88  ? 16.460  -61.753 19.721  1.00 46.86  ? 74  GLY   L N   1 
ATOM   5010 C  CA  . GLY   C 1 88  ? 16.597  -62.745 20.795  1.00 53.27  ? 74  GLY   L CA  1 
ATOM   5011 C  C   . GLY   C 1 88  ? 15.580  -62.537 21.909  1.00 56.65  ? 74  GLY   L C   1 
ATOM   5012 O  O   . GLY   C 1 88  ? 14.873  -61.526 21.966  1.00 51.22  ? 74  GLY   L O   1 
ATOM   5013 N  N   . PRO   C 1 89  ? 15.509  -63.491 22.856  1.00 54.72  ? 75  PRO   L N   1 
ATOM   5014 C  CA  . PRO   C 1 89  ? 14.502  -63.433 23.920  1.00 57.32  ? 75  PRO   L CA  1 
ATOM   5015 C  C   . PRO   C 1 89  ? 14.660  -62.206 24.837  1.00 50.80  ? 75  PRO   L C   1 
ATOM   5016 O  O   . PRO   C 1 89  ? 13.661  -61.740 25.325  1.00 54.27  ? 75  PRO   L O   1 
ATOM   5017 C  CB  . PRO   C 1 89  ? 14.732  -64.749 24.694  1.00 63.58  ? 75  PRO   L CB  1 
ATOM   5018 C  CG  . PRO   C 1 89  ? 16.185  -65.116 24.387  1.00 65.81  ? 75  PRO   L CG  1 
ATOM   5019 C  CD  . PRO   C 1 89  ? 16.425  -64.640 22.967  1.00 56.11  ? 75  PRO   L CD  1 
ATOM   5020 N  N   . GLN   C 1 90  ? 15.894  -61.717 25.026  1.00 53.20  ? 76  GLN   L N   1 
ATOM   5021 C  CA  . GLN   C 1 90  ? 16.225  -60.464 25.765  1.00 57.13  ? 76  GLN   L CA  1 
ATOM   5022 C  C   . GLN   C 1 90  ? 16.330  -59.277 24.787  1.00 53.72  ? 76  GLN   L C   1 
ATOM   5023 O  O   . GLN   C 1 90  ? 16.877  -58.267 25.187  1.00 48.97  ? 76  GLN   L O   1 
ATOM   5024 C  CB  . GLN   C 1 90  ? 17.557  -60.594 26.515  1.00 66.87  ? 76  GLN   L CB  1 
ATOM   5025 C  CG  . GLN   C 1 90  ? 17.448  -61.244 27.895  1.00 79.24  ? 76  GLN   L CG  1 
ATOM   5026 C  CD  . GLN   C 1 90  ? 17.456  -62.752 27.833  1.00 88.98  ? 76  GLN   L CD  1 
ATOM   5027 O  OE1 . GLN   C 1 90  ? 18.124  -63.360 26.998  1.00 96.05  ? 76  GLN   L OE1 1 
ATOM   5028 N  NE2 . GLN   C 1 90  ? 16.714  -63.376 28.730  1.00 93.72  ? 76  GLN   L NE2 1 
ATOM   5029 N  N   . GLY   C 1 91  ? 15.846  -59.409 23.551  1.00 48.91  ? 77  GLY   L N   1 
ATOM   5030 C  CA  . GLY   C 1 91  ? 16.038  -58.378 22.512  1.00 53.72  ? 77  GLY   L CA  1 
ATOM   5031 C  C   . GLY   C 1 91  ? 15.221  -57.108 22.769  1.00 43.42  ? 77  GLY   L C   1 
ATOM   5032 O  O   . GLY   C 1 91  ? 14.170  -57.190 23.399  1.00 45.16  ? 77  GLY   L O   1 
ATOM   5033 N  N   . ARG   C 1 92  ? 15.685  -55.966 22.260  1.00 44.10  ? 78  ARG   L N   1 
ATOM   5034 C  CA  . ARG   C 1 92  ? 14.913  -54.691 22.208  1.00 40.32  ? 78  ARG   L CA  1 
ATOM   5035 C  C   . ARG   C 1 92  ? 13.722  -54.805 21.252  1.00 41.24  ? 78  ARG   L C   1 
ATOM   5036 O  O   . ARG   C 1 92  ? 12.754  -54.060 21.441  1.00 47.27  ? 78  ARG   L O   1 
ATOM   5037 C  CB  . ARG   C 1 92  ? 15.830  -53.548 21.778  1.00 41.80  ? 78  ARG   L CB  1 
ATOM   5038 C  CG  . ARG   C 1 92  ? 16.939  -53.249 22.773  1.00 42.40  ? 78  ARG   L CG  1 
ATOM   5039 C  CD  . ARG   C 1 92  ? 17.723  -52.073 22.265  1.00 38.70  ? 78  ARG   L CD  1 
ATOM   5040 N  NE  . ARG   C 1 92  ? 18.754  -51.636 23.198  1.00 38.24  ? 78  ARG   L NE  1 
ATOM   5041 C  CZ  . ARG   C 1 92  ? 19.523  -50.581 23.008  1.00 42.77  ? 78  ARG   L CZ  1 
ATOM   5042 N  NH1 . ARG   C 1 92  ? 19.382  -49.813 21.929  1.00 40.99  ? 78  ARG   L NH1 1 
ATOM   5043 N  NH2 . ARG   C 1 92  ? 20.441  -50.277 23.899  1.00 41.03  ? 78  ARG   L NH2 1 
ATOM   5044 N  N   . TRP   C 1 93  ? 13.800  -55.616 20.202  1.00 40.02  ? 79  TRP   L N   1 
ATOM   5045 C  CA  . TRP   C 1 93  ? 12.701  -55.700 19.222  1.00 38.42  ? 79  TRP   L CA  1 
ATOM   5046 C  C   . TRP   C 1 93  ? 11.617  -56.568 19.850  1.00 46.01  ? 79  TRP   L C   1 
ATOM   5047 O  O   . TRP   C 1 93  ? 11.965  -57.607 20.438  1.00 45.85  ? 79  TRP   L O   1 
ATOM   5048 C  CB  . TRP   C 1 93  ? 13.162  -56.259 17.866  1.00 40.13  ? 79  TRP   L CB  1 
ATOM   5049 C  CG  . TRP   C 1 93  ? 14.095  -55.387 17.068  1.00 40.29  ? 79  TRP   L CG  1 
ATOM   5050 C  CD1 . TRP   C 1 93  ? 14.680  -54.209 17.448  1.00 35.14  ? 79  TRP   L CD1 1 
ATOM   5051 C  CD2 . TRP   C 1 93  ? 14.570  -55.643 15.735  1.00 37.58  ? 79  TRP   L CD2 1 
ATOM   5052 N  NE1 . TRP   C 1 93  ? 15.500  -53.733 16.451  1.00 37.34  ? 79  TRP   L NE1 1 
ATOM   5053 C  CE2 . TRP   C 1 93  ? 15.434  -54.580 15.382  1.00 35.04  ? 79  TRP   L CE2 1 
ATOM   5054 C  CE3 . TRP   C 1 93  ? 14.358  -56.664 14.807  1.00 40.02  ? 79  TRP   L CE3 1 
ATOM   5055 C  CZ2 . TRP   C 1 93  ? 16.115  -54.538 14.168  1.00 36.53  ? 79  TRP   L CZ2 1 
ATOM   5056 C  CZ3 . TRP   C 1 93  ? 14.987  -56.595 13.586  1.00 38.97  ? 79  TRP   L CZ3 1 
ATOM   5057 C  CH2 . TRP   C 1 93  ? 15.881  -55.566 13.288  1.00 39.10  ? 79  TRP   L CH2 1 
ATOM   5058 N  N   . ALA   C 1 94  ? 10.366  -56.145 19.752  1.00 42.97  ? 80  ALA   L N   1 
ATOM   5059 C  CA  . ALA   C 1 94  ? 9.178   -56.931 20.134  1.00 46.41  ? 80  ALA   L CA  1 
ATOM   5060 C  C   . ALA   C 1 94  ? 9.177   -58.251 19.357  1.00 46.68  ? 80  ALA   L C   1 
ATOM   5061 O  O   . ALA   C 1 94  ? 9.678   -58.296 18.223  1.00 44.56  ? 80  ALA   L O   1 
ATOM   5062 C  CB  . ALA   C 1 94  ? 7.932   -56.117 19.862  1.00 49.32  ? 80  ALA   L CB  1 
ATOM   5063 N  N   . GLU   C 1 95  ? 8.560   -59.288 19.914  1.00 47.39  ? 81  GLU   L N   1 
ATOM   5064 C  CA  . GLU   C 1 95  ? 8.571   -60.653 19.340  1.00 51.57  ? 81  GLU   L CA  1 
ATOM   5065 C  C   . GLU   C 1 95  ? 7.908   -60.635 17.950  1.00 49.39  ? 81  GLU   L C   1 
ATOM   5066 O  O   . GLU   C 1 95  ? 8.448   -61.299 17.032  1.00 46.57  ? 81  GLU   L O   1 
ATOM   5067 C  CB  . GLU   C 1 95  ? 7.928   -61.618 20.347  1.00 57.91  ? 81  GLU   L CB  1 
ATOM   5068 C  CG  . GLU   C 1 95  ? 7.918   -63.083 19.903  1.00 62.39  ? 81  GLU   L CG  1 
ATOM   5069 C  CD  . GLU   C 1 95  ? 9.273   -63.670 19.540  1.00 63.33  ? 81  GLU   L CD  1 
ATOM   5070 O  OE1 . GLU   C 1 95  ? 10.275  -63.339 20.211  1.00 70.19  ? 81  GLU   L OE1 1 
ATOM   5071 O  OE2 . GLU   C 1 95  ? 9.333   -64.435 18.572  1.00 71.38  ? 81  GLU   L OE2 1 
ATOM   5072 N  N   . SER   C 1 96  ? 6.793   -59.918 17.767  1.00 42.09  ? 82  SER   L N   1 
ATOM   5073 C  CA  . SER   C 1 96  ? 6.128   -59.781 16.448  1.00 45.29  ? 82  SER   L CA  1 
ATOM   5074 C  C   . SER   C 1 96  ? 7.115   -59.183 15.426  1.00 40.79  ? 82  SER   L C   1 
ATOM   5075 O  O   . SER   C 1 96  ? 7.136   -59.652 14.284  1.00 42.44  ? 82  SER   L O   1 
ATOM   5076 C  CB  . SER   C 1 96  ? 4.858   -58.936 16.526  1.00 50.61  ? 82  SER   L CB  1 
ATOM   5077 O  OG  . SER   C 1 96  ? 5.165   -57.617 16.969  1.00 46.20  ? 82  SER   L OG  1 
ATOM   5078 N  N   . THR   C 1 97  ? 7.875   -58.156 15.803  1.00 40.69  ? 83  THR   L N   1 
ATOM   5079 C  CA  . THR   C 1 97  ? 8.869   -57.492 14.920  1.00 40.70  ? 83  THR   L CA  1 
ATOM   5080 C  C   . THR   C 1 97  ? 9.954   -58.519 14.513  1.00 46.06  ? 83  THR   L C   1 
ATOM   5081 O  O   . THR   C 1 97  ? 10.260  -58.672 13.294  1.00 41.44  ? 83  THR   L O   1 
ATOM   5082 C  CB  . THR   C 1 97  ? 9.460   -56.292 15.644  1.00 41.61  ? 83  THR   L CB  1 
ATOM   5083 O  OG1 . THR   C 1 97  ? 8.382   -55.501 16.143  1.00 38.51  ? 83  THR   L OG1 1 
ATOM   5084 C  CG2 . THR   C 1 97  ? 10.392  -55.482 14.765  1.00 41.36  ? 83  THR   L CG2 1 
ATOM   5085 N  N   . GLN   C 1 98  ? 10.464  -59.264 15.484  1.00 42.42  ? 84  GLN   L N   1 
ATOM   5086 C  CA  . GLN   C 1 98  ? 11.535  -60.275 15.246  1.00 43.02  ? 84  GLN   L CA  1 
ATOM   5087 C  C   . GLN   C 1 98  ? 11.053  -61.355 14.284  1.00 42.69  ? 84  GLN   L C   1 
ATOM   5088 O  O   . GLN   C 1 98  ? 11.874  -61.845 13.492  1.00 44.76  ? 84  GLN   L O   1 
ATOM   5089 C  CB  . GLN   C 1 98  ? 11.977  -60.936 16.539  1.00 42.30  ? 84  GLN   L CB  1 
ATOM   5090 C  CG  . GLN   C 1 98  ? 12.599  -59.951 17.502  1.00 39.34  ? 84  GLN   L CG  1 
ATOM   5091 C  CD  . GLN   C 1 98  ? 13.366  -60.675 18.584  1.00 45.15  ? 84  GLN   L CD  1 
ATOM   5092 O  OE1 . GLN   C 1 98  ? 13.985  -61.700 18.334  1.00 44.85  ? 84  GLN   L OE1 1 
ATOM   5093 N  NE2 . GLN   C 1 98  ? 13.378  -60.109 19.784  1.00 41.29  ? 84  GLN   L NE2 1 
ATOM   5094 N  N   . GLN   C 1 99  ? 9.765   -61.671 14.287  1.00 43.67  ? 85  GLN   L N   1 
ATOM   5095 C  CA  . GLN   C 1 99  ? 9.233   -62.759 13.436  1.00 46.90  ? 85  GLN   L CA  1 
ATOM   5096 C  C   . GLN   C 1 99  ? 8.931   -62.248 12.013  1.00 46.45  ? 85  GLN   L C   1 
ATOM   5097 O  O   . GLN   C 1 99  ? 8.984   -63.064 11.046  1.00 46.11  ? 85  GLN   L O   1 
ATOM   5098 C  CB  . GLN   C 1 99  ? 8.031   -63.379 14.143  1.00 50.61  ? 85  GLN   L CB  1 
ATOM   5099 C  CG  . GLN   C 1 99  ? 8.426   -64.197 15.375  1.00 62.48  ? 85  GLN   L CG  1 
ATOM   5100 C  CD  . GLN   C 1 99  ? 7.373   -65.203 15.780  1.00 73.95  ? 85  GLN   L CD  1 
ATOM   5101 O  OE1 . GLN   C 1 99  ? 7.014   -65.306 16.951  1.00 88.28  ? 85  GLN   L OE1 1 
ATOM   5102 N  NE2 . GLN   C 1 99  ? 6.872   -65.968 14.819  1.00 82.75  ? 85  GLN   L NE2 1 
ATOM   5103 N  N   . MET   C 1 100 ? 8.596   -60.969 11.847  1.00 41.76  ? 86  MET   L N   1 
ATOM   5104 C  CA  . MET   C 1 100 ? 8.227   -60.427 10.508  1.00 42.52  ? 86  MET   L CA  1 
ATOM   5105 C  C   . MET   C 1 100 ? 9.445   -59.815 9.794   1.00 37.25  ? 86  MET   L C   1 
ATOM   5106 O  O   . MET   C 1 100 ? 9.410   -59.768 8.561   1.00 38.39  ? 86  MET   L O   1 
ATOM   5107 C  CB  . MET   C 1 100 ? 7.164   -59.327 10.626  1.00 44.52  ? 86  MET   L CB  1 
ATOM   5108 C  CG  . MET   C 1 100 ? 5.752   -59.817 10.576  1.00 53.06  ? 86  MET   L CG  1 
ATOM   5109 S  SD  . MET   C 1 100 ? 4.544   -58.424 10.623  1.00 51.69  ? 86  MET   L SD  1 
ATOM   5110 C  CE  . MET   C 1 100 ? 4.859   -57.725 12.246  1.00 54.95  ? 86  MET   L CE  1 
ATOM   5111 N  N   . PHE   C 1 101 ? 10.449  -59.366 10.542  1.00 38.44  ? 87  PHE   L N   1 
ATOM   5112 C  CA  . PHE   C 1 101 ? 11.650  -58.616 10.060  1.00 40.04  ? 87  PHE   L CA  1 
ATOM   5113 C  C   . PHE   C 1 101 ? 12.930  -59.170 10.692  1.00 38.88  ? 87  PHE   L C   1 
ATOM   5114 O  O   . PHE   C 1 101 ? 13.812  -58.415 11.064  1.00 40.11  ? 87  PHE   L O   1 
ATOM   5115 C  CB  . PHE   C 1 101 ? 11.481  -57.123 10.372  1.00 42.91  ? 87  PHE   L CB  1 
ATOM   5116 C  CG  . PHE   C 1 101 ? 10.161  -56.564 9.890   1.00 39.74  ? 87  PHE   L CG  1 
ATOM   5117 C  CD1 . PHE   C 1 101 ? 9.947   -56.313 8.550   1.00 42.57  ? 87  PHE   L CD1 1 
ATOM   5118 C  CD2 . PHE   C 1 101 ? 9.123   -56.306 10.784  1.00 46.55  ? 87  PHE   L CD2 1 
ATOM   5119 C  CE1 . PHE   C 1 101 ? 8.738   -55.783 8.117   1.00 51.28  ? 87  PHE   L CE1 1 
ATOM   5120 C  CE2 . PHE   C 1 101 ? 7.914   -55.776 10.352  1.00 44.69  ? 87  PHE   L CE2 1 
ATOM   5121 C  CZ  . PHE   C 1 101 ? 7.716   -55.534 9.011   1.00 45.91  ? 87  PHE   L CZ  1 
ATOM   5122 N  N   . PRO   C 1 102 ? 13.121  -60.513 10.780  1.00 38.00  ? 88  PRO   L N   1 
ATOM   5123 C  CA  . PRO   C 1 102 ? 14.328  -61.059 11.408  1.00 38.20  ? 88  PRO   L CA  1 
ATOM   5124 C  C   . PRO   C 1 102 ? 15.637  -60.547 10.768  1.00 37.61  ? 88  PRO   L C   1 
ATOM   5125 O  O   . PRO   C 1 102 ? 15.802  -60.571 9.550   1.00 41.96  ? 88  PRO   L O   1 
ATOM   5126 C  CB  . PRO   C 1 102 ? 14.173  -62.596 11.228  1.00 40.81  ? 88  PRO   L CB  1 
ATOM   5127 C  CG  . PRO   C 1 102 ? 13.239  -62.739 10.047  1.00 44.24  ? 88  PRO   L CG  1 
ATOM   5128 C  CD  . PRO   C 1 102 ? 12.282  -61.546 10.160  1.00 41.35  ? 88  PRO   L CD  1 
ATOM   5129 N  N   . TRP   C 1 103 ? 16.554  -60.076 11.614  1.00 37.46  ? 89  TRP   L N   1 
ATOM   5130 C  CA  . TRP   C 1 103 ? 17.909  -59.624 11.241  1.00 37.75  ? 89  TRP   L CA  1 
ATOM   5131 C  C   . TRP   C 1 103 ? 18.917  -60.729 11.600  1.00 45.73  ? 89  TRP   L C   1 
ATOM   5132 O  O   . TRP   C 1 103 ? 18.950  -61.151 12.777  1.00 38.33  ? 89  TRP   L O   1 
ATOM   5133 C  CB  . TRP   C 1 103 ? 18.221  -58.355 12.019  1.00 37.42  ? 89  TRP   L CB  1 
ATOM   5134 C  CG  . TRP   C 1 103 ? 19.562  -57.775 11.736  1.00 37.04  ? 89  TRP   L CG  1 
ATOM   5135 C  CD1 . TRP   C 1 103 ? 20.129  -57.576 10.517  1.00 38.94  ? 89  TRP   L CD1 1 
ATOM   5136 C  CD2 . TRP   C 1 103 ? 20.496  -57.273 12.697  1.00 40.98  ? 89  TRP   L CD2 1 
ATOM   5137 N  NE1 . TRP   C 1 103 ? 21.360  -57.014 10.663  1.00 35.96  ? 89  TRP   L NE1 1 
ATOM   5138 C  CE2 . TRP   C 1 103 ? 21.613  -56.810 11.984  1.00 35.84  ? 89  TRP   L CE2 1 
ATOM   5139 C  CE3 . TRP   C 1 103 ? 20.521  -57.219 14.089  1.00 38.72  ? 89  TRP   L CE3 1 
ATOM   5140 C  CZ2 . TRP   C 1 103 ? 22.717  -56.235 12.608  1.00 41.69  ? 89  TRP   L CZ2 1 
ATOM   5141 C  CZ3 . TRP   C 1 103 ? 21.609  -56.666 14.700  1.00 37.76  ? 89  TRP   L CZ3 1 
ATOM   5142 C  CH2 . TRP   C 1 103 ? 22.692  -56.167 13.976  1.00 37.08  ? 89  TRP   L CH2 1 
ATOM   5143 N  N   . THR   C 1 104 ? 19.730  -61.152 10.654  1.00 41.40  ? 90  THR   L N   1 
ATOM   5144 C  CA  . THR   C 1 104 ? 20.822  -62.130 10.939  1.00 45.68  ? 90  THR   L CA  1 
ATOM   5145 C  C   . THR   C 1 104 ? 22.140  -61.408 10.698  1.00 44.88  ? 90  THR   L C   1 
ATOM   5146 O  O   . THR   C 1 104 ? 22.290  -60.743 9.638   1.00 44.63  ? 90  THR   L O   1 
ATOM   5147 C  CB  . THR   C 1 104 ? 20.717  -63.387 10.065  1.00 48.66  ? 90  THR   L CB  1 
ATOM   5148 O  OG1 . THR   C 1 104 ? 20.874  -62.876 8.755   1.00 52.16  ? 90  THR   L OG1 1 
ATOM   5149 C  CG2 . THR   C 1 104 ? 19.406  -64.132 10.138  1.00 50.24  ? 90  THR   L CG2 1 
ATOM   5150 N  N   . ALA   C 1 105 ? 23.047  -61.479 11.661  1.00 41.95  ? 91  ALA   L N   1 
ATOM   5151 C  CA  . ALA   C 1 105 ? 24.357  -60.814 11.604  1.00 48.85  ? 91  ALA   L CA  1 
ATOM   5152 C  C   . ALA   C 1 105 ? 25.358  -61.597 12.466  1.00 48.57  ? 91  ALA   L C   1 
ATOM   5153 O  O   . ALA   C 1 105 ? 25.068  -61.871 13.608  1.00 46.67  ? 91  ALA   L O   1 
ATOM   5154 C  CB  . ALA   C 1 105 ? 24.231  -59.382 12.089  1.00 48.75  ? 91  ALA   L CB  1 
ATOM   5155 N  N   . THR   C 1 106 ? 26.536  -61.830 11.929  1.00 49.08  ? 92  THR   L N   1 
ATOM   5156 C  CA  . THR   C 1 106 ? 27.740  -62.262 12.673  1.00 52.73  ? 92  THR   L CA  1 
ATOM   5157 C  C   . THR   C 1 106 ? 28.290  -61.044 13.419  1.00 55.92  ? 92  THR   L C   1 
ATOM   5158 O  O   . THR   C 1 106 ? 27.997  -59.875 12.994  1.00 47.96  ? 92  THR   L O   1 
ATOM   5159 C  CB  . THR   C 1 106 ? 28.728  -62.877 11.669  1.00 56.25  ? 92  THR   L CB  1 
ATOM   5160 O  OG1 . THR   C 1 106 ? 29.144  -61.882 10.732  1.00 57.25  ? 92  THR   L OG1 1 
ATOM   5161 C  CG2 . THR   C 1 106 ? 28.131  -64.045 10.912  1.00 53.64  ? 92  THR   L CG2 1 
ATOM   5162 N  N   . GLU   C 1 107 ? 29.069  -61.254 14.483  1.00 48.03  ? 93  GLU   L N   1 
ATOM   5163 C  CA  . GLU   C 1 107 ? 29.688  -60.120 15.240  1.00 52.03  ? 93  GLU   L CA  1 
ATOM   5164 C  C   . GLU   C 1 107 ? 30.505  -59.201 14.326  1.00 48.67  ? 93  GLU   L C   1 
ATOM   5165 O  O   . GLU   C 1 107 ? 30.613  -57.980 14.668  1.00 44.56  ? 93  GLU   L O   1 
ATOM   5166 C  CB  . GLU   C 1 107 ? 30.619  -60.589 16.356  1.00 61.54  ? 93  GLU   L CB  1 
ATOM   5167 C  CG  . GLU   C 1 107 ? 29.879  -60.755 17.664  1.00 80.69  ? 93  GLU   L CG  1 
ATOM   5168 C  CD  . GLU   C 1 107 ? 30.668  -61.446 18.753  1.00 97.00  ? 93  GLU   L CD  1 
ATOM   5169 O  OE1 . GLU   C 1 107 ? 31.569  -62.270 18.430  1.00 108.37 ? 93  GLU   L OE1 1 
ATOM   5170 O  OE2 . GLU   C 1 107 ? 30.379  -61.145 19.922  1.00 109.49 ? 93  GLU   L OE2 1 
ATOM   5171 N  N   . GLU   C 1 108 ? 31.119  -59.730 13.259  1.00 44.60  ? 94  GLU   L N   1 
ATOM   5172 C  CA  . GLU   C 1 108 ? 31.948  -58.878 12.357  1.00 48.94  ? 94  GLU   L CA  1 
ATOM   5173 C  C   . GLU   C 1 108 ? 31.023  -57.861 11.613  1.00 45.36  ? 94  GLU   L C   1 
ATOM   5174 O  O   . GLU   C 1 108 ? 31.540  -56.798 11.178  1.00 40.47  ? 94  GLU   L O   1 
ATOM   5175 C  CB  . GLU   C 1 108 ? 32.840  -59.738 11.449  1.00 58.36  ? 94  GLU   L CB  1 
ATOM   5176 C  CG  . GLU   C 1 108 ? 32.085  -60.584 10.426  1.00 76.63  ? 94  GLU   L CG  1 
ATOM   5177 C  CD  . GLU   C 1 108 ? 32.816  -60.937 9.125   1.00 89.99  ? 94  GLU   L CD  1 
ATOM   5178 O  OE1 . GLU   C 1 108 ? 32.314  -61.834 8.393   1.00 86.29  ? 94  GLU   L OE1 1 
ATOM   5179 O  OE2 . GLU   C 1 108 ? 33.854  -60.293 8.809   1.00 85.82  ? 94  GLU   L OE2 1 
ATOM   5180 N  N   . CYS   C 1 109 ? 29.715  -58.134 11.546  1.00 39.46  ? 95  CYS   L N   1 
ATOM   5181 C  CA  . CYS   C 1 109 ? 28.708  -57.306 10.844  1.00 44.53  ? 95  CYS   L CA  1 
ATOM   5182 C  C   . CYS   C 1 109 ? 28.239  -56.135 11.716  1.00 42.94  ? 95  CYS   L C   1 
ATOM   5183 O  O   . CYS   C 1 109 ? 27.702  -55.163 11.112  1.00 42.26  ? 95  CYS   L O   1 
ATOM   5184 C  CB  . CYS   C 1 109 ? 27.502  -58.124 10.417  1.00 43.65  ? 95  CYS   L CB  1 
ATOM   5185 S  SG  . CYS   C 1 109 ? 27.787  -59.203 8.990   1.00 51.37  ? 95  CYS   L SG  1 
ATOM   5186 N  N   . TYR   C 1 110 ? 28.483  -56.140 13.038  1.00 40.68  ? 96  TYR   L N   1 
ATOM   5187 C  CA  . TYR   C 1 110 ? 27.990  -55.050 13.929  1.00 42.14  ? 96  TYR   L CA  1 
ATOM   5188 C  C   . TYR   C 1 110 ? 28.750  -53.786 13.597  1.00 44.05  ? 96  TYR   L C   1 
ATOM   5189 O  O   . TYR   C 1 110 ? 29.951  -53.871 13.349  1.00 43.06  ? 96  TYR   L O   1 
ATOM   5190 C  CB  . TYR   C 1 110 ? 28.160  -55.317 15.422  1.00 42.12  ? 96  TYR   L CB  1 
ATOM   5191 C  CG  . TYR   C 1 110 ? 27.429  -56.525 15.942  1.00 46.72  ? 96  TYR   L CG  1 
ATOM   5192 C  CD1 . TYR   C 1 110 ? 26.291  -57.000 15.314  1.00 49.41  ? 96  TYR   L CD1 1 
ATOM   5193 C  CD2 . TYR   C 1 110 ? 27.842  -57.154 17.106  1.00 51.48  ? 96  TYR   L CD2 1 
ATOM   5194 C  CE1 . TYR   C 1 110 ? 25.610  -58.105 15.793  1.00 49.38  ? 96  TYR   L CE1 1 
ATOM   5195 C  CE2 . TYR   C 1 110 ? 27.160  -58.248 17.609  1.00 48.95  ? 96  TYR   L CE2 1 
ATOM   5196 C  CZ  . TYR   C 1 110 ? 26.057  -58.731 16.937  1.00 48.90  ? 96  TYR   L CZ  1 
ATOM   5197 O  OH  . TYR   C 1 110 ? 25.355  -59.775 17.424  1.00 50.69  ? 96  TYR   L OH  1 
ATOM   5198 N  N   . LEU   C 1 111 ? 28.044  -52.653 13.541  1.00 39.83  ? 97  LEU   L N   1 
ATOM   5199 C  CA  . LEU   C 1 111 ? 28.652  -51.405 13.037  1.00 40.77  ? 97  LEU   L CA  1 
ATOM   5200 C  C   . LEU   C 1 111 ? 29.891  -51.066 13.862  1.00 39.73  ? 97  LEU   L C   1 
ATOM   5201 O  O   . LEU   C 1 111 ? 30.867  -50.616 13.270  1.00 37.72  ? 97  LEU   L O   1 
ATOM   5202 C  CB  . LEU   C 1 111 ? 27.630  -50.261 13.089  1.00 41.08  ? 97  LEU   L CB  1 
ATOM   5203 C  CG  . LEU   C 1 111 ? 28.175  -48.887 12.719  1.00 37.73  ? 97  LEU   L CG  1 
ATOM   5204 C  CD1 . LEU   C 1 111 ? 28.636  -48.853 11.256  1.00 40.51  ? 97  LEU   L CD1 1 
ATOM   5205 C  CD2 . LEU   C 1 111 ? 27.091  -47.834 12.983  1.00 41.38  ? 97  LEU   L CD2 1 
ATOM   5206 N  N   . HIS   C 1 112 ? 29.863  -51.254 15.189  1.00 39.92  ? 98  HIS   L N   1 
ATOM   5207 C  CA  . HIS   C 1 112 ? 31.041  -50.893 16.037  1.00 44.77  ? 98  HIS   L CA  1 
ATOM   5208 C  C   . HIS   C 1 112 ? 32.284  -51.711 15.595  1.00 36.86  ? 98  HIS   L C   1 
ATOM   5209 O  O   . HIS   C 1 112 ? 33.340  -51.100 15.486  1.00 40.64  ? 98  HIS   L O   1 
ATOM   5210 C  CB  . HIS   C 1 112 ? 30.744  -50.913 17.567  1.00 48.15  ? 98  HIS   L CB  1 
ATOM   5211 C  CG  . HIS   C 1 112 ? 30.637  -52.260 18.197  1.00 65.45  ? 98  HIS   L CG  1 
ATOM   5212 N  ND1 . HIS   C 1 112 ? 29.467  -53.021 18.150  1.00 79.03  ? 98  HIS   L ND1 1 
ATOM   5213 C  CD2 . HIS   C 1 112 ? 31.529  -52.985 18.910  1.00 67.87  ? 98  HIS   L CD2 1 
ATOM   5214 C  CE1 . HIS   C 1 112 ? 29.649  -54.162 18.781  1.00 72.40  ? 98  HIS   L CE1 1 
ATOM   5215 N  NE2 . HIS   C 1 112 ? 30.911  -54.163 19.261  1.00 72.24  ? 98  HIS   L NE2 1 
ATOM   5216 N  N   . ASN   C 1 113 ? 32.132  -52.983 15.246  1.00 37.57  ? 99  ASN   L N   1 
ATOM   5217 C  CA  . ASN   C 1 113 ? 33.274  -53.813 14.754  1.00 42.77  ? 99  ASN   L CA  1 
ATOM   5218 C  C   . ASN   C 1 113 ? 33.694  -53.413 13.332  1.00 44.95  ? 99  ASN   L C   1 
ATOM   5219 O  O   . ASN   C 1 113 ? 34.913  -53.257 13.099  1.00 42.67  ? 99  ASN   L O   1 
ATOM   5220 C  CB  . ASN   C 1 113 ? 32.934  -55.289 14.855  1.00 38.84  ? 99  ASN   L CB  1 
ATOM   5221 C  CG  . ASN   C 1 113 ? 32.780  -55.659 16.309  1.00 44.02  ? 99  ASN   L CG  1 
ATOM   5222 O  OD1 . ASN   C 1 113 ? 33.424  -55.035 17.147  1.00 49.06  ? 99  ASN   L OD1 1 
ATOM   5223 N  ND2 . ASN   C 1 113 ? 31.907  -56.607 16.601  1.00 45.19  ? 99  ASN   L ND2 1 
ATOM   5224 N  N   . ARG   C 1 114 ? 32.742  -53.176 12.425  1.00 44.79  ? 100 ARG   L N   1 
ATOM   5225 C  CA  . ARG   C 1 114 ? 33.073  -52.703 11.052  1.00 41.20  ? 100 ARG   L CA  1 
ATOM   5226 C  C   . ARG   C 1 114 ? 33.920  -51.444 11.167  1.00 38.87  ? 100 ARG   L C   1 
ATOM   5227 O  O   . ARG   C 1 114 ? 34.935  -51.318 10.446  1.00 39.18  ? 100 ARG   L O   1 
ATOM   5228 C  CB  . ARG   C 1 114 ? 31.798  -52.429 10.247  1.00 40.30  ? 100 ARG   L CB  1 
ATOM   5229 C  CG  . ARG   C 1 114 ? 31.092  -53.671 9.765   1.00 39.85  ? 100 ARG   L CG  1 
ATOM   5230 C  CD  . ARG   C 1 114 ? 31.930  -54.516 8.804   1.00 41.96  ? 100 ARG   L CD  1 
ATOM   5231 N  NE  . ARG   C 1 114 ? 31.139  -55.656 8.338   1.00 41.63  ? 100 ARG   L NE  1 
ATOM   5232 C  CZ  . ARG   C 1 114 ? 31.651  -56.816 7.929   1.00 42.99  ? 100 ARG   L CZ  1 
ATOM   5233 N  NH1 . ARG   C 1 114 ? 32.964  -57.005 7.954   1.00 42.24  ? 100 ARG   L NH1 1 
ATOM   5234 N  NH2 . ARG   C 1 114 ? 30.843  -57.756 7.493   1.00 44.77  ? 100 ARG   L NH2 1 
ATOM   5235 N  N   . LEU   C 1 115 ? 33.560  -50.513 12.052  1.00 40.44  ? 101 LEU   L N   1 
ATOM   5236 C  CA  . LEU   C 1 115 ? 34.310  -49.233 12.154  1.00 37.60  ? 101 LEU   L CA  1 
ATOM   5237 C  C   . LEU   C 1 115 ? 35.700  -49.491 12.800  1.00 40.40  ? 101 LEU   L C   1 
ATOM   5238 O  O   . LEU   C 1 115 ? 36.703  -48.873 12.370  1.00 42.62  ? 101 LEU   L O   1 
ATOM   5239 C  CB  . LEU   C 1 115 ? 33.514  -48.219 12.983  1.00 38.06  ? 101 LEU   L CB  1 
ATOM   5240 C  CG  . LEU   C 1 115 ? 32.273  -47.614 12.295  1.00 37.07  ? 101 LEU   L CG  1 
ATOM   5241 C  CD1 . LEU   C 1 115 ? 31.420  -46.831 13.287  1.00 39.10  ? 101 LEU   L CD1 1 
ATOM   5242 C  CD2 . LEU   C 1 115 ? 32.676  -46.693 11.158  1.00 37.71  ? 101 LEU   L CD2 1 
ATOM   5243 N  N   . GLU   C 1 116 ? 35.748  -50.289 13.856  1.00 39.91  ? 102 GLU   L N   1 
ATOM   5244 C  CA  . GLU   C 1 116 ? 37.020  -50.631 14.557  1.00 46.70  ? 102 GLU   L CA  1 
ATOM   5245 C  C   . GLU   C 1 116 ? 38.016  -51.219 13.525  1.00 43.73  ? 102 GLU   L C   1 
ATOM   5246 O  O   . GLU   C 1 116 ? 39.198  -50.829 13.536  1.00 42.35  ? 102 GLU   L O   1 
ATOM   5247 C  CB  . GLU   C 1 116 ? 36.713  -51.619 15.689  1.00 51.17  ? 102 GLU   L CB  1 
ATOM   5248 C  CG  . GLU   C 1 116 ? 37.957  -52.198 16.365  1.00 55.11  ? 102 GLU   L CG  1 
ATOM   5249 C  CD  . GLU   C 1 116 ? 37.642  -53.200 17.471  1.00 74.83  ? 102 GLU   L CD  1 
ATOM   5250 O  OE1 . GLU   C 1 116 ? 36.446  -53.549 17.671  1.00 80.45  ? 102 GLU   L OE1 1 
ATOM   5251 O  OE2 . GLU   C 1 116 ? 38.596  -53.637 18.140  1.00 96.51  ? 102 GLU   L OE2 1 
ATOM   5252 N  N   . GLN   C 1 117 ? 37.551  -52.058 12.602  1.00 43.64  ? 103 GLN   L N   1 
ATOM   5253 C  CA  . GLN   C 1 117 ? 38.437  -52.678 11.581  1.00 42.29  ? 103 GLN   L CA  1 
ATOM   5254 C  C   . GLN   C 1 117 ? 38.965  -51.599 10.661  1.00 46.63  ? 103 GLN   L C   1 
ATOM   5255 O  O   . GLN   C 1 117 ? 39.903  -51.878 9.941   1.00 46.99  ? 103 GLN   L O   1 
ATOM   5256 C  CB  . GLN   C 1 117 ? 37.703  -53.766 10.815  1.00 45.80  ? 103 GLN   L CB  1 
ATOM   5257 C  CG  . GLN   C 1 117 ? 37.601  -55.068 11.582  1.00 46.98  ? 103 GLN   L CG  1 
ATOM   5258 C  CD  . GLN   C 1 117 ? 38.973  -55.506 12.056  1.00 56.13  ? 103 GLN   L CD  1 
ATOM   5259 O  OE1 . GLN   C 1 117 ? 39.227  -55.527 13.251  1.00 58.68  ? 103 GLN   L OE1 1 
ATOM   5260 N  NE2 . GLN   C 1 117 ? 39.870  -55.808 11.131  1.00 54.20  ? 103 GLN   L NE2 1 
ATOM   5261 N  N   . LEU   C 1 118 ? 38.353  -50.414 10.641  1.00 39.65  ? 104 LEU   L N   1 
ATOM   5262 C  CA  . LEU   C 1 118 ? 38.882  -49.284 9.844   1.00 39.91  ? 104 LEU   L CA  1 
ATOM   5263 C  C   . LEU   C 1 118 ? 39.645  -48.328 10.754  1.00 36.46  ? 104 LEU   L C   1 
ATOM   5264 O  O   . LEU   C 1 118 ? 40.054  -47.244 10.269  1.00 40.20  ? 104 LEU   L O   1 
ATOM   5265 C  CB  . LEU   C 1 118 ? 37.722  -48.579 9.126   1.00 41.53  ? 104 LEU   L CB  1 
ATOM   5266 C  CG  . LEU   C 1 118 ? 36.922  -49.429 8.144   1.00 41.16  ? 104 LEU   L CG  1 
ATOM   5267 C  CD1 . LEU   C 1 118 ? 35.711  -48.651 7.604   1.00 43.11  ? 104 LEU   L CD1 1 
ATOM   5268 C  CD2 . LEU   C 1 118 ? 37.814  -49.872 6.987   1.00 43.21  ? 104 LEU   L CD2 1 
ATOM   5269 N  N   . LYS   C 1 119 ? 39.880  -48.721 12.009  1.00 40.83  ? 105 LYS   L N   1 
ATOM   5270 C  CA  . LYS   C 1 119 ? 40.570  -47.875 13.026  1.00 45.79  ? 105 LYS   L CA  1 
ATOM   5271 C  C   . LYS   C 1 119 ? 39.748  -46.595 13.224  1.00 43.89  ? 105 LYS   L C   1 
ATOM   5272 O  O   . LYS   C 1 119 ? 40.320  -45.499 13.391  1.00 38.33  ? 105 LYS   L O   1 
ATOM   5273 C  CB  . LYS   C 1 119 ? 42.051  -47.633 12.684  1.00 54.11  ? 105 LYS   L CB  1 
ATOM   5274 C  CG  . LYS   C 1 119 ? 42.849  -48.919 12.442  1.00 62.25  ? 105 LYS   L CG  1 
ATOM   5275 C  CD  . LYS   C 1 119 ? 44.328  -48.818 12.792  1.00 75.25  ? 105 LYS   L CD  1 
ATOM   5276 C  CE  . LYS   C 1 119 ? 45.246  -49.457 11.763  1.00 80.69  ? 105 LYS   L CE  1 
ATOM   5277 N  NZ  . LYS   C 1 119 ? 46.610  -49.665 12.308  1.00 82.97  ? 105 LYS   L NZ  1 
ATOM   5278 N  N   . VAL   C 1 120 ? 38.425  -46.738 13.218  1.00 42.72  ? 106 VAL   L N   1 
ATOM   5279 C  CA  . VAL   C 1 120 ? 37.515  -45.570 13.407  1.00 46.02  ? 106 VAL   L CA  1 
ATOM   5280 C  C   . VAL   C 1 120 ? 36.750  -45.840 14.687  1.00 43.29  ? 106 VAL   L C   1 
ATOM   5281 O  O   . VAL   C 1 120 ? 36.081  -46.890 14.758  1.00 47.30  ? 106 VAL   L O   1 
ATOM   5282 C  CB  . VAL   C 1 120 ? 36.563  -45.332 12.223  1.00 43.89  ? 106 VAL   L CB  1 
ATOM   5283 C  CG1 . VAL   C 1 120 ? 35.528  -44.253 12.575  1.00 44.99  ? 106 VAL   L CG1 1 
ATOM   5284 C  CG2 . VAL   C 1 120 ? 37.330  -44.949 10.963  1.00 43.31  ? 106 VAL   L CG2 1 
ATOM   5285 N  N   . ARG   C 1 121 ? 36.930  -44.948 15.660  1.00 44.30  ? 107 ARG   L N   1 
ATOM   5286 C  CA  . ARG   C 1 121 ? 36.217  -44.989 16.962  1.00 52.41  ? 107 ARG   L CA  1 
ATOM   5287 C  C   . ARG   C 1 121 ? 34.909  -44.213 16.814  1.00 44.79  ? 107 ARG   L C   1 
ATOM   5288 O  O   . ARG   C 1 121 ? 34.883  -43.230 16.083  1.00 40.60  ? 107 ARG   L O   1 
ATOM   5289 C  CB  . ARG   C 1 121 ? 37.081  -44.322 18.036  1.00 58.63  ? 107 ARG   L CB  1 
ATOM   5290 C  CG  . ARG   C 1 121 ? 38.438  -44.986 18.255  1.00 72.81  ? 107 ARG   L CG  1 
ATOM   5291 C  CD  . ARG   C 1 121 ? 38.869  -45.018 19.711  1.00 84.21  ? 107 ARG   L CD  1 
ATOM   5292 N  NE  . ARG   C 1 121 ? 37.768  -45.507 20.545  1.00 106.00 ? 107 ARG   L NE  1 
ATOM   5293 C  CZ  . ARG   C 1 121 ? 37.742  -45.533 21.876  1.00 113.62 ? 107 ARG   L CZ  1 
ATOM   5294 N  NH1 . ARG   C 1 121 ? 36.657  -45.986 22.490  1.00 104.21 ? 107 ARG   L NH1 1 
ATOM   5295 N  NH2 . ARG   C 1 121 ? 38.785  -45.113 22.580  1.00 113.92 ? 107 ARG   L NH2 1 
ATOM   5296 N  N   . PRO   C 1 122 ? 33.844  -44.576 17.556  1.00 46.71  ? 108 PRO   L N   1 
ATOM   5297 C  CA  . PRO   C 1 122 ? 32.606  -43.787 17.557  1.00 46.16  ? 108 PRO   L CA  1 
ATOM   5298 C  C   . PRO   C 1 122 ? 32.850  -42.288 17.741  1.00 44.26  ? 108 PRO   L C   1 
ATOM   5299 O  O   . PRO   C 1 122 ? 32.307  -41.514 16.983  1.00 40.96  ? 108 PRO   L O   1 
ATOM   5300 C  CB  . PRO   C 1 122 ? 31.837  -44.374 18.741  1.00 47.31  ? 108 PRO   L CB  1 
ATOM   5301 C  CG  . PRO   C 1 122 ? 32.291  -45.835 18.756  1.00 49.84  ? 108 PRO   L CG  1 
ATOM   5302 C  CD  . PRO   C 1 122 ? 33.760  -45.770 18.431  1.00 45.10  ? 108 PRO   L CD  1 
ATOM   5303 N  N   . GLU   C 1 123 ? 33.708  -41.909 18.697  1.00 43.59  ? 109 GLU   L N   1 
ATOM   5304 C  CA  . GLU   C 1 123 ? 34.031  -40.489 18.984  1.00 43.95  ? 109 GLU   L CA  1 
ATOM   5305 C  C   . GLU   C 1 123 ? 34.675  -39.795 17.784  1.00 44.82  ? 109 GLU   L C   1 
ATOM   5306 O  O   . GLU   C 1 123 ? 34.774  -38.564 17.832  1.00 43.00  ? 109 GLU   L O   1 
ATOM   5307 C  CB  . GLU   C 1 123 ? 34.971  -40.362 20.182  1.00 56.77  ? 109 GLU   L CB  1 
ATOM   5308 C  CG  . GLU   C 1 123 ? 36.389  -40.817 19.873  1.00 61.63  ? 109 GLU   L CG  1 
ATOM   5309 C  CD  . GLU   C 1 123 ? 37.193  -41.171 21.104  1.00 69.44  ? 109 GLU   L CD  1 
ATOM   5310 O  OE1 . GLU   C 1 123 ? 37.542  -40.243 21.838  1.00 74.76  ? 109 GLU   L OE1 1 
ATOM   5311 O  OE2 . GLU   C 1 123 ? 37.445  -42.371 21.318  1.00 77.36  ? 109 GLU   L OE2 1 
ATOM   5312 N  N   . ASP   C 1 124 ? 35.199  -40.524 16.787  1.00 45.96  ? 110 ASP   L N   1 
ATOM   5313 C  CA  . ASP   C 1 124 ? 35.827  -39.888 15.593  1.00 46.33  ? 110 ASP   L CA  1 
ATOM   5314 C  C   . ASP   C 1 124 ? 34.758  -39.381 14.593  1.00 42.17  ? 110 ASP   L C   1 
ATOM   5315 O  O   . ASP   C 1 124 ? 35.137  -38.663 13.631  1.00 42.73  ? 110 ASP   L O   1 
ATOM   5316 C  CB  . ASP   C 1 124 ? 36.811  -40.852 14.904  1.00 49.17  ? 110 ASP   L CB  1 
ATOM   5317 C  CG  . ASP   C 1 124 ? 37.987  -41.264 15.783  1.00 59.33  ? 110 ASP   L CG  1 
ATOM   5318 O  OD1 . ASP   C 1 124 ? 38.456  -40.386 16.560  1.00 56.46  ? 110 ASP   L OD1 1 
ATOM   5319 O  OD2 . ASP   C 1 124 ? 38.380  -42.463 15.728  1.00 50.71  ? 110 ASP   L OD2 1 
ATOM   5320 N  N   . ILE   C 1 125 ? 33.489  -39.749 14.757  1.00 41.47  ? 111 ILE   L N   1 
ATOM   5321 C  CA  . ILE   C 1 125 ? 32.424  -39.375 13.773  1.00 44.80  ? 111 ILE   L CA  1 
ATOM   5322 C  C   . ILE   C 1 125 ? 31.950  -37.949 14.086  1.00 39.94  ? 111 ILE   L C   1 
ATOM   5323 O  O   . ILE   C 1 125 ? 31.432  -37.716 15.165  1.00 46.36  ? 111 ILE   L O   1 
ATOM   5324 C  CB  . ILE   C 1 125 ? 31.258  -40.384 13.767  1.00 42.35  ? 111 ILE   L CB  1 
ATOM   5325 C  CG1 . ILE   C 1 125 ? 31.727  -41.832 13.556  1.00 39.86  ? 111 ILE   L CG1 1 
ATOM   5326 C  CG2 . ILE   C 1 125 ? 30.214  -39.966 12.731  1.00 42.26  ? 111 ILE   L CG2 1 
ATOM   5327 C  CD1 . ILE   C 1 125 ? 32.455  -42.081 12.268  1.00 37.45  ? 111 ILE   L CD1 1 
ATOM   5328 N  N   . ARG   C 1 126 ? 32.098  -37.037 13.148  1.00 39.98  ? 112 ARG   L N   1 
ATOM   5329 C  CA  . ARG   C 1 126 ? 31.664  -35.639 13.283  1.00 41.52  ? 112 ARG   L CA  1 
ATOM   5330 C  C   . ARG   C 1 126 ? 30.165  -35.500 12.948  1.00 43.86  ? 112 ARG   L C   1 
ATOM   5331 O  O   . ARG   C 1 126 ? 29.461  -34.744 13.688  1.00 37.83  ? 112 ARG   L O   1 
ATOM   5332 C  CB  . ARG   C 1 126 ? 32.434  -34.772 12.301  1.00 41.62  ? 112 ARG   L CB  1 
ATOM   5333 C  CG  . ARG   C 1 126 ? 32.133  -33.299 12.467  1.00 47.17  ? 112 ARG   L CG  1 
ATOM   5334 C  CD  . ARG   C 1 126 ? 32.856  -32.459 11.441  1.00 52.60  ? 112 ARG   L CD  1 
ATOM   5335 N  NE  . ARG   C 1 126 ? 32.613  -31.053 11.707  1.00 62.91  ? 112 ARG   L NE  1 
ATOM   5336 C  CZ  . ARG   C 1 126 ? 32.841  -30.059 10.853  1.00 62.48  ? 112 ARG   L CZ  1 
ATOM   5337 N  NH1 . ARG   C 1 126 ? 33.338  -30.297 9.654   1.00 60.65  ? 112 ARG   L NH1 1 
ATOM   5338 N  NH2 . ARG   C 1 126 ? 32.559  -28.820 11.203  1.00 62.00  ? 112 ARG   L NH2 1 
ATOM   5339 N  N   . TYR   C 1 127 ? 29.700  -36.133 11.856  1.00 39.62  ? 113 TYR   L N   1 
ATOM   5340 C  CA  . TYR   C 1 127 ? 28.255  -36.140 11.491  1.00 37.16  ? 113 TYR   L CA  1 
ATOM   5341 C  C   . TYR   C 1 127 ? 27.725  -37.547 11.274  1.00 37.41  ? 113 TYR   L C   1 
ATOM   5342 O  O   . TYR   C 1 127 ? 28.349  -38.364 10.569  1.00 35.78  ? 113 TYR   L O   1 
ATOM   5343 C  CB  . TYR   C 1 127 ? 28.037  -35.359 10.202  1.00 36.23  ? 113 TYR   L CB  1 
ATOM   5344 C  CG  . TYR   C 1 127 ? 28.396  -33.910 10.304  1.00 36.92  ? 113 TYR   L CG  1 
ATOM   5345 C  CD1 . TYR   C 1 127 ? 27.680  -33.073 11.141  1.00 41.34  ? 113 TYR   L CD1 1 
ATOM   5346 C  CD2 . TYR   C 1 127 ? 29.452  -33.376 9.585   1.00 40.20  ? 113 TYR   L CD2 1 
ATOM   5347 C  CE1 . TYR   C 1 127 ? 27.967  -31.718 11.222  1.00 41.02  ? 113 TYR   L CE1 1 
ATOM   5348 C  CE2 . TYR   C 1 127 ? 29.773  -32.033 9.675   1.00 42.51  ? 113 TYR   L CE2 1 
ATOM   5349 C  CZ  . TYR   C 1 127 ? 29.016  -31.205 10.482  1.00 44.91  ? 113 TYR   L CZ  1 
ATOM   5350 O  OH  . TYR   C 1 127 ? 29.318  -29.893 10.562  1.00 48.34  ? 113 TYR   L OH  1 
ATOM   5351 N  N   . VAL   C 1 128 ? 26.511  -37.760 11.765  1.00 33.41  ? 114 VAL   L N   1 
ATOM   5352 C  CA  . VAL   C 1 128 ? 25.673  -38.922 11.394  1.00 32.86  ? 114 VAL   L CA  1 
ATOM   5353 C  C   . VAL   C 1 128 ? 24.443  -38.401 10.652  1.00 37.84  ? 114 VAL   L C   1 
ATOM   5354 O  O   . VAL   C 1 128 ? 23.755  -37.509 11.202  1.00 36.73  ? 114 VAL   L O   1 
ATOM   5355 C  CB  . VAL   C 1 128 ? 25.275  -39.762 12.607  1.00 34.81  ? 114 VAL   L CB  1 
ATOM   5356 C  CG1 . VAL   C 1 128 ? 24.565  -41.015 12.165  1.00 36.32  ? 114 VAL   L CG1 1 
ATOM   5357 C  CG2 . VAL   C 1 128 ? 26.486  -40.113 13.461  1.00 40.83  ? 114 VAL   L CG2 1 
ATOM   5358 N  N   . VAL   C 1 129 ? 24.255  -38.853 9.418   1.00 30.98  ? 115 VAL   L N   1 
ATOM   5359 C  CA  . VAL   C 1 129 ? 23.019  -38.554 8.648   1.00 34.31  ? 115 VAL   L CA  1 
ATOM   5360 C  C   . VAL   C 1 129 ? 22.101  -39.766 8.818   1.00 36.34  ? 115 VAL   L C   1 
ATOM   5361 O  O   . VAL   C 1 129 ? 22.422  -40.849 8.352   1.00 32.48  ? 115 VAL   L O   1 
ATOM   5362 C  CB  . VAL   C 1 129 ? 23.307  -38.174 7.185   1.00 32.66  ? 115 VAL   L CB  1 
ATOM   5363 C  CG1 . VAL   C 1 129 ? 22.004  -37.909 6.442   1.00 34.23  ? 115 VAL   L CG1 1 
ATOM   5364 C  CG2 . VAL   C 1 129 ? 24.259  -36.981 7.082   1.00 38.13  ? 115 VAL   L CG2 1 
ATOM   5365 N  N   . ALA   C 1 130 ? 20.997  -39.594 9.550   1.00 35.22  ? 116 ALA   L N   1 
ATOM   5366 C  CA  . ALA   C 1 130 ? 19.945  -40.621 9.693   1.00 33.32  ? 116 ALA   L CA  1 
ATOM   5367 C  C   . ALA   C 1 130 ? 18.958  -40.464 8.544   1.00 37.32  ? 116 ALA   L C   1 
ATOM   5368 O  O   . ALA   C 1 130 ? 18.193  -39.477 8.575   1.00 36.45  ? 116 ALA   L O   1 
ATOM   5369 C  CB  . ALA   C 1 130 ? 19.299  -40.433 11.022  1.00 34.27  ? 116 ALA   L CB  1 
ATOM   5370 N  N   . SER   C 1 131 ? 18.989  -41.357 7.555   1.00 34.86  ? 117 SER   L N   1 
ATOM   5371 C  CA  . SER   C 1 131 ? 18.065  -41.339 6.394   1.00 34.62  ? 117 SER   L CA  1 
ATOM   5372 C  C   . SER   C 1 131 ? 16.632  -41.182 6.933   1.00 33.77  ? 117 SER   L C   1 
ATOM   5373 O  O   . SER   C 1 131 ? 15.821  -40.492 6.326   1.00 33.37  ? 117 SER   L O   1 
ATOM   5374 C  CB  . SER   C 1 131 ? 18.253  -42.586 5.490   1.00 36.85  ? 117 SER   L CB  1 
ATOM   5375 O  OG  . SER   C 1 131 ? 17.785  -43.778 6.107   1.00 36.66  ? 117 SER   L OG  1 
ATOM   5376 N  N   . HIS   C 1 132 ? 16.347  -41.913 7.999   1.00 32.72  ? 118 HIS   L N   1 
ATOM   5377 C  CA  . HIS   C 1 132 ? 15.085  -41.977 8.758   1.00 31.13  ? 118 HIS   L CA  1 
ATOM   5378 C  C   . HIS   C 1 132 ? 15.338  -42.808 10.014  1.00 32.35  ? 118 HIS   L C   1 
ATOM   5379 O  O   . HIS   C 1 132 ? 16.501  -43.165 10.272  1.00 33.28  ? 118 HIS   L O   1 
ATOM   5380 C  CB  . HIS   C 1 132 ? 13.927  -42.443 7.895   1.00 31.38  ? 118 HIS   L CB  1 
ATOM   5381 C  CG  . HIS   C 1 132 ? 14.030  -43.836 7.420   1.00 30.04  ? 118 HIS   L CG  1 
ATOM   5382 N  ND1 . HIS   C 1 132 ? 15.145  -44.322 6.714   1.00 32.76  ? 118 HIS   L ND1 1 
ATOM   5383 C  CD2 . HIS   C 1 132 ? 13.126  -44.828 7.451   1.00 31.94  ? 118 HIS   L CD2 1 
ATOM   5384 C  CE1 . HIS   C 1 132 ? 14.888  -45.560 6.354   1.00 33.28  ? 118 HIS   L CE1 1 
ATOM   5385 N  NE2 . HIS   C 1 132 ? 13.693  -45.913 6.849   1.00 31.03  ? 118 HIS   L NE2 1 
ATOM   5386 N  N   . LEU   C 1 133 ? 14.328  -43.034 10.836  1.00 33.27  ? 119 LEU   L N   1 
ATOM   5387 C  CA  . LEU   C 1 133 ? 14.577  -43.554 12.211  1.00 30.98  ? 119 LEU   L CA  1 
ATOM   5388 C  C   . LEU   C 1 133 ? 13.976  -44.949 12.388  1.00 29.28  ? 119 LEU   L C   1 
ATOM   5389 O  O   . LEU   C 1 133 ? 13.780  -45.387 13.531  1.00 32.46  ? 119 LEU   L O   1 
ATOM   5390 C  CB  . LEU   C 1 133 ? 14.000  -42.504 13.164  1.00 31.06  ? 119 LEU   L CB  1 
ATOM   5391 C  CG  . LEU   C 1 133 ? 14.810  -41.220 13.291  1.00 30.47  ? 119 LEU   L CG  1 
ATOM   5392 C  CD1 . LEU   C 1 133 ? 14.201  -40.280 14.315  1.00 33.13  ? 119 LEU   L CD1 1 
ATOM   5393 C  CD2 . LEU   C 1 133 ? 16.260  -41.478 13.632  1.00 33.35  ? 119 LEU   L CD2 1 
ATOM   5394 N  N   . HIS   C 1 134 ? 13.757  -45.661 11.301  1.00 31.18  ? 120 HIS   L N   1 
ATOM   5395 C  CA  . HIS   C 1 134 ? 13.323  -47.075 11.321  1.00 32.56  ? 120 HIS   L CA  1 
ATOM   5396 C  C   . HIS   C 1 134 ? 14.415  -47.944 11.979  1.00 32.61  ? 120 HIS   L C   1 
ATOM   5397 O  O   . HIS   C 1 134 ? 15.554  -47.541 11.961  1.00 31.43  ? 120 HIS   L O   1 
ATOM   5398 C  CB  . HIS   C 1 134 ? 13.021  -47.580 9.914   1.00 31.77  ? 120 HIS   L CB  1 
ATOM   5399 C  CG  . HIS   C 1 134 ? 11.653  -47.319 9.431   1.00 32.14  ? 120 HIS   L CG  1 
ATOM   5400 N  ND1 . HIS   C 1 134 ? 11.341  -47.346 8.095   1.00 34.54  ? 120 HIS   L ND1 1 
ATOM   5401 C  CD2 . HIS   C 1 134 ? 10.528  -46.945 10.094  1.00 37.08  ? 120 HIS   L CD2 1 
ATOM   5402 C  CE1 . HIS   C 1 134 ? 10.043  -47.090 7.968   1.00 33.48  ? 120 HIS   L CE1 1 
ATOM   5403 N  NE2 . HIS   C 1 134 ? 9.538   -46.820 9.180   1.00 33.58  ? 120 HIS   L NE2 1 
ATOM   5404 N  N   . LEU   C 1 135 ? 14.017  -49.112 12.503  1.00 32.57  ? 121 LEU   L N   1 
ATOM   5405 C  CA  . LEU   C 1 135 ? 14.828  -50.086 13.291  1.00 35.19  ? 121 LEU   L CA  1 
ATOM   5406 C  C   . LEU   C 1 135 ? 16.113  -50.500 12.566  1.00 36.70  ? 121 LEU   L C   1 
ATOM   5407 O  O   . LEU   C 1 135 ? 17.118  -50.725 13.270  1.00 35.53  ? 121 LEU   L O   1 
ATOM   5408 C  CB  . LEU   C 1 135 ? 13.963  -51.295 13.659  1.00 33.97  ? 121 LEU   L CB  1 
ATOM   5409 C  CG  . LEU   C 1 135 ? 13.570  -52.288 12.571  1.00 36.12  ? 121 LEU   L CG  1 
ATOM   5410 C  CD1 . LEU   C 1 135 ? 12.686  -53.396 13.166  1.00 37.31  ? 121 LEU   L CD1 1 
ATOM   5411 C  CD2 . LEU   C 1 135 ? 12.842  -51.638 11.407  1.00 40.41  ? 121 LEU   L CD2 1 
ATOM   5412 N  N   . ASP   C 1 136 ? 16.125  -50.513 11.234  1.00 37.44  ? 122 ASP   L N   1 
ATOM   5413 C  CA  . ASP   C 1 136 ? 17.259  -51.036 10.429  1.00 36.12  ? 122 ASP   L CA  1 
ATOM   5414 C  C   . ASP   C 1 136 ? 18.178  -49.897 9.964   1.00 40.57  ? 122 ASP   L C   1 
ATOM   5415 O  O   . ASP   C 1 136 ? 19.132  -50.202 9.218   1.00 36.63  ? 122 ASP   L O   1 
ATOM   5416 C  CB  . ASP   C 1 136 ? 16.716  -51.891 9.274   1.00 39.24  ? 122 ASP   L CB  1 
ATOM   5417 C  CG  . ASP   C 1 136 ? 15.746  -51.159 8.363   1.00 39.70  ? 122 ASP   L CG  1 
ATOM   5418 O  OD1 . ASP   C 1 136 ? 14.851  -50.435 8.889   1.00 35.59  ? 122 ASP   L OD1 1 
ATOM   5419 O  OD2 . ASP   C 1 136 ? 15.846  -51.345 7.145   1.00 41.35  ? 122 ASP   L OD2 1 
ATOM   5420 N  N   . HIS   C 1 137 ? 17.954  -48.648 10.401  1.00 32.91  ? 123 HIS   L N   1 
ATOM   5421 C  CA  . HIS   C 1 137 ? 18.753  -47.466 9.994   1.00 31.74  ? 123 HIS   L CA  1 
ATOM   5422 C  C   . HIS   C 1 137 ? 19.247  -46.673 11.201  1.00 30.37  ? 123 HIS   L C   1 
ATOM   5423 O  O   . HIS   C 1 137 ? 20.307  -46.026 11.096  1.00 31.24  ? 123 HIS   L O   1 
ATOM   5424 C  CB  . HIS   C 1 137 ? 17.982  -46.574 8.985   1.00 36.05  ? 123 HIS   L CB  1 
ATOM   5425 C  CG  . HIS   C 1 137 ? 17.570  -47.296 7.746   1.00 34.44  ? 123 HIS   L CG  1 
ATOM   5426 N  ND1 . HIS   C 1 137 ? 18.310  -47.226 6.588   1.00 34.92  ? 123 HIS   L ND1 1 
ATOM   5427 C  CD2 . HIS   C 1 137 ? 16.547  -48.165 7.502   1.00 33.21  ? 123 HIS   L CD2 1 
ATOM   5428 C  CE1 . HIS   C 1 137 ? 17.747  -47.986 5.669   1.00 33.78  ? 123 HIS   L CE1 1 
ATOM   5429 N  NE2 . HIS   C 1 137 ? 16.666  -48.604 6.200   1.00 32.76  ? 123 HIS   L NE2 1 
ATOM   5430 N  N   . ALA   C 1 138 ? 18.516  -46.662 12.308  1.00 36.02  ? 124 ALA   L N   1 
ATOM   5431 C  CA  . ALA   C 1 138 ? 18.824  -45.789 13.464  1.00 36.77  ? 124 ALA   L CA  1 
ATOM   5432 C  C   . ALA   C 1 138 ? 19.264  -46.628 14.685  1.00 36.76  ? 124 ALA   L C   1 
ATOM   5433 O  O   . ALA   C 1 138 ? 19.409  -46.045 15.766  1.00 34.94  ? 124 ALA   L O   1 
ATOM   5434 C  CB  . ALA   C 1 138 ? 17.599  -44.929 13.772  1.00 35.99  ? 124 ALA   L CB  1 
ATOM   5435 N  N   . GLY   C 1 139 ? 19.486  -47.935 14.515  1.00 38.71  ? 125 GLY   L N   1 
ATOM   5436 C  CA  . GLY   C 1 139 ? 19.809  -48.878 15.609  1.00 40.16  ? 125 GLY   L CA  1 
ATOM   5437 C  C   . GLY   C 1 139 ? 21.041  -48.532 16.443  1.00 41.19  ? 125 GLY   L C   1 
ATOM   5438 O  O   . GLY   C 1 139 ? 21.003  -48.802 17.688  1.00 43.28  ? 125 GLY   L O   1 
ATOM   5439 N  N   . CYS   C 1 140 ? 22.084  -47.908 15.873  1.00 35.86  ? 126 CYS   L N   1 
ATOM   5440 C  CA  . CYS   C 1 140 ? 23.318  -47.586 16.642  1.00 34.43  ? 126 CYS   L CA  1 
ATOM   5441 C  C   . CYS   C 1 140 ? 23.558  -46.100 16.750  1.00 33.86  ? 126 CYS   L C   1 
ATOM   5442 O  O   . CYS   C 1 140 ? 24.685  -45.693 17.108  1.00 36.73  ? 126 CYS   L O   1 
ATOM   5443 C  CB  . CYS   C 1 140 ? 24.558  -48.292 16.098  1.00 38.62  ? 126 CYS   L CB  1 
ATOM   5444 S  SG  . CYS   C 1 140 ? 24.327  -50.067 15.889  1.00 42.43  ? 126 CYS   L SG  1 
ATOM   5445 N  N   . LEU   C 1 141 ? 22.538  -45.263 16.566  1.00 35.31  ? 127 LEU   L N   1 
ATOM   5446 C  CA  . LEU   C 1 141 ? 22.751  -43.808 16.816  1.00 32.18  ? 127 LEU   L CA  1 
ATOM   5447 C  C   . LEU   C 1 141 ? 23.344  -43.570 18.208  1.00 32.04  ? 127 LEU   L C   1 
ATOM   5448 O  O   . LEU   C 1 141 ? 24.119  -42.618 18.351  1.00 33.54  ? 127 LEU   L O   1 
ATOM   5449 C  CB  . LEU   C 1 141 ? 21.413  -43.054 16.710  1.00 35.00  ? 127 LEU   L CB  1 
ATOM   5450 C  CG  . LEU   C 1 141 ? 20.901  -42.819 15.296  1.00 37.72  ? 127 LEU   L CG  1 
ATOM   5451 C  CD1 . LEU   C 1 141 ? 19.525  -42.132 15.376  1.00 42.30  ? 127 LEU   L CD1 1 
ATOM   5452 C  CD2 . LEU   C 1 141 ? 21.884  -41.982 14.507  1.00 38.05  ? 127 LEU   L CD2 1 
ATOM   5453 N  N   . GLU   C 1 142 ? 22.914  -44.336 19.215  1.00 37.95  ? 128 GLU   L N   1 
ATOM   5454 C  CA  . GLU   C 1 142 ? 23.331  -44.128 20.639  1.00 42.53  ? 128 GLU   L CA  1 
ATOM   5455 C  C   . GLU   C 1 142 ? 24.864  -44.179 20.824  1.00 41.74  ? 128 GLU   L C   1 
ATOM   5456 O  O   . GLU   C 1 142 ? 25.330  -43.567 21.778  1.00 39.67  ? 128 GLU   L O   1 
ATOM   5457 C  CB  . GLU   C 1 142 ? 22.700  -45.156 21.588  1.00 42.12  ? 128 GLU   L CB  1 
ATOM   5458 C  CG  . GLU   C 1 142 ? 23.083  -46.583 21.309  1.00 42.24  ? 128 GLU   L CG  1 
ATOM   5459 C  CD  . GLU   C 1 142 ? 22.136  -47.546 22.011  1.00 45.45  ? 128 GLU   L CD  1 
ATOM   5460 O  OE1 . GLU   C 1 142 ? 22.504  -48.140 23.062  1.00 47.30  ? 128 GLU   L OE1 1 
ATOM   5461 O  OE2 . GLU   C 1 142 ? 21.035  -47.718 21.523  1.00 43.07  ? 128 GLU   L OE2 1 
ATOM   5462 N  N   . MET   C 1 143 ? 25.627  -44.819 19.927  1.00 40.22  ? 129 MET   L N   1 
ATOM   5463 C  CA  . MET   C 1 143 ? 27.125  -44.831 19.997  1.00 42.61  ? 129 MET   L CA  1 
ATOM   5464 C  C   . MET   C 1 143 ? 27.705  -43.436 19.772  1.00 40.86  ? 129 MET   L C   1 
ATOM   5465 O  O   . MET   C 1 143 ? 28.865  -43.153 20.190  1.00 39.82  ? 129 MET   L O   1 
ATOM   5466 C  CB  . MET   C 1 143 ? 27.721  -45.728 18.899  1.00 46.40  ? 129 MET   L CB  1 
ATOM   5467 C  CG  . MET   C 1 143 ? 27.547  -47.226 19.136  1.00 54.83  ? 129 MET   L CG  1 
ATOM   5468 S  SD  . MET   C 1 143 ? 27.963  -48.198 17.637  1.00 56.14  ? 129 MET   L SD  1 
ATOM   5469 C  CE  . MET   C 1 143 ? 29.511  -47.447 17.147  1.00 60.33  ? 129 MET   L CE  1 
ATOM   5470 N  N   . PHE   C 1 144 ? 27.035  -42.581 19.000  1.00 38.66  ? 130 PHE   L N   1 
ATOM   5471 C  CA  . PHE   C 1 144 ? 27.736  -41.403 18.429  1.00 36.82  ? 130 PHE   L CA  1 
ATOM   5472 C  C   . PHE   C 1 144 ? 27.455  -40.170 19.275  1.00 44.03  ? 130 PHE   L C   1 
ATOM   5473 O  O   . PHE   C 1 144 ? 26.880  -39.178 18.785  1.00 41.45  ? 130 PHE   L O   1 
ATOM   5474 C  CB  . PHE   C 1 144 ? 27.430  -41.290 16.940  1.00 36.29  ? 130 PHE   L CB  1 
ATOM   5475 C  CG  . PHE   C 1 144 ? 27.749  -42.558 16.197  1.00 39.27  ? 130 PHE   L CG  1 
ATOM   5476 C  CD1 . PHE   C 1 144 ? 29.073  -42.928 15.967  1.00 38.09  ? 130 PHE   L CD1 1 
ATOM   5477 C  CD2 . PHE   C 1 144 ? 26.738  -43.404 15.777  1.00 35.76  ? 130 PHE   L CD2 1 
ATOM   5478 C  CE1 . PHE   C 1 144 ? 29.364  -44.100 15.296  1.00 38.37  ? 130 PHE   L CE1 1 
ATOM   5479 C  CE2 . PHE   C 1 144 ? 27.046  -44.600 15.150  1.00 40.96  ? 130 PHE   L CE2 1 
ATOM   5480 C  CZ  . PHE   C 1 144 ? 28.356  -44.956 14.926  1.00 38.72  ? 130 PHE   L CZ  1 
ATOM   5481 N  N   . THR   C 1 145 ? 28.017  -40.169 20.479  1.00 38.29  ? 131 THR   L N   1 
ATOM   5482 C  CA  . THR   C 1 145 ? 27.852  -39.103 21.488  1.00 39.79  ? 131 THR   L CA  1 
ATOM   5483 C  C   . THR   C 1 145 ? 28.715  -37.881 21.183  1.00 43.42  ? 131 THR   L C   1 
ATOM   5484 O  O   . THR   C 1 145 ? 28.474  -36.856 21.835  1.00 41.68  ? 131 THR   L O   1 
ATOM   5485 C  CB  . THR   C 1 145 ? 28.142  -39.666 22.881  1.00 44.41  ? 131 THR   L CB  1 
ATOM   5486 O  OG1 . THR   C 1 145 ? 29.382  -40.367 22.800  1.00 43.79  ? 131 THR   L OG1 1 
ATOM   5487 C  CG2 . THR   C 1 145 ? 27.078  -40.622 23.346  1.00 44.72  ? 131 THR   L CG2 1 
ATOM   5488 N  N   . ASN   C 1 146 ? 29.633  -37.943 20.216  1.00 39.48  ? 132 ASN   L N   1 
ATOM   5489 C  CA  . ASN   C 1 146 ? 30.537  -36.818 19.867  1.00 43.95  ? 132 ASN   L CA  1 
ATOM   5490 C  C   . ASN   C 1 146 ? 30.124  -36.193 18.517  1.00 46.34  ? 132 ASN   L C   1 
ATOM   5491 O  O   . ASN   C 1 146 ? 30.785  -35.226 18.076  1.00 43.51  ? 132 ASN   L O   1 
ATOM   5492 C  CB  . ASN   C 1 146 ? 32.000  -37.286 19.903  1.00 50.38  ? 132 ASN   L CB  1 
ATOM   5493 C  CG  . ASN   C 1 146 ? 32.998  -36.170 20.122  1.00 56.53  ? 132 ASN   L CG  1 
ATOM   5494 O  OD1 . ASN   C 1 146 ? 34.126  -36.258 19.640  1.00 63.65  ? 132 ASN   L OD1 1 
ATOM   5495 N  ND2 . ASN   C 1 146 ? 32.604  -35.100 20.792  1.00 53.36  ? 132 ASN   L ND2 1 
ATOM   5496 N  N   . ALA   C 1 147 ? 29.056  -36.702 17.900  1.00 38.73  ? 133 ALA   L N   1 
ATOM   5497 C  CA  . ALA   C 1 147 ? 28.601  -36.306 16.552  1.00 40.12  ? 133 ALA   L CA  1 
ATOM   5498 C  C   . ALA   C 1 147 ? 27.428  -35.315 16.671  1.00 38.84  ? 133 ALA   L C   1 
ATOM   5499 O  O   . ALA   C 1 147 ? 26.743  -35.295 17.726  1.00 38.01  ? 133 ALA   L O   1 
ATOM   5500 C  CB  . ALA   C 1 147 ? 28.220  -37.552 15.788  1.00 42.32  ? 133 ALA   L CB  1 
ATOM   5501 N  N   . THR   C 1 148 ? 27.197  -34.534 15.610  1.00 37.89  ? 134 THR   L N   1 
ATOM   5502 C  CA  . THR   C 1 148 ? 25.875  -33.898 15.313  1.00 37.50  ? 134 THR   L CA  1 
ATOM   5503 C  C   . THR   C 1 148 ? 25.045  -34.912 14.522  1.00 36.06  ? 134 THR   L C   1 
ATOM   5504 O  O   . THR   C 1 148 ? 25.564  -35.415 13.532  1.00 33.18  ? 134 THR   L O   1 
ATOM   5505 C  CB  . THR   C 1 148 ? 26.033  -32.586 14.560  1.00 39.36  ? 134 THR   L CB  1 
ATOM   5506 O  OG1 . THR   C 1 148 ? 26.882  -31.819 15.391  1.00 39.98  ? 134 THR   L OG1 1 
ATOM   5507 C  CG2 . THR   C 1 148 ? 24.720  -31.874 14.289  1.00 42.66  ? 134 THR   L CG2 1 
ATOM   5508 N  N   . ILE   C 1 149 ? 23.877  -35.296 15.036  1.00 32.10  ? 135 ILE   L N   1 
ATOM   5509 C  CA  . ILE   C 1 149 ? 22.961  -36.267 14.380  1.00 33.38  ? 135 ILE   L CA  1 
ATOM   5510 C  C   . ILE   C 1 149 ? 21.993  -35.446 13.527  1.00 34.82  ? 135 ILE   L C   1 
ATOM   5511 O  O   . ILE   C 1 149 ? 21.173  -34.712 14.099  1.00 34.18  ? 135 ILE   L O   1 
ATOM   5512 C  CB  . ILE   C 1 149 ? 22.206  -37.144 15.388  1.00 35.26  ? 135 ILE   L CB  1 
ATOM   5513 C  CG1 . ILE   C 1 149 ? 23.121  -37.778 16.443  1.00 36.69  ? 135 ILE   L CG1 1 
ATOM   5514 C  CG2 . ILE   C 1 149 ? 21.415  -38.191 14.626  1.00 36.73  ? 135 ILE   L CG2 1 
ATOM   5515 C  CD1 . ILE   C 1 149 ? 24.229  -38.673 15.886  1.00 38.71  ? 135 ILE   L CD1 1 
ATOM   5516 N  N   . ILE   C 1 150 ? 22.115  -35.570 12.211  1.00 32.26  ? 136 ILE   L N   1 
ATOM   5517 C  CA  . ILE   C 1 150 ? 21.249  -34.903 11.222  1.00 33.35  ? 136 ILE   L CA  1 
ATOM   5518 C  C   . ILE   C 1 150 ? 20.068  -35.811 10.902  1.00 33.87  ? 136 ILE   L C   1 
ATOM   5519 O  O   . ILE   C 1 150 ? 20.239  -36.975 10.480  1.00 33.33  ? 136 ILE   L O   1 
ATOM   5520 C  CB  . ILE   C 1 150 ? 22.048  -34.443 10.005  1.00 34.23  ? 136 ILE   L CB  1 
ATOM   5521 C  CG1 . ILE   C 1 150 ? 23.212  -33.542 10.456  1.00 35.08  ? 136 ILE   L CG1 1 
ATOM   5522 C  CG2 . ILE   C 1 150 ? 21.117  -33.719 9.038   1.00 34.80  ? 136 ILE   L CG2 1 
ATOM   5523 C  CD1 . ILE   C 1 150 ? 24.217  -33.340 9.421   1.00 40.27  ? 136 ILE   L CD1 1 
ATOM   5524 N  N   . VAL   C 1 151 ? 18.872  -35.289 11.160  1.00 29.82  ? 137 VAL   L N   1 
ATOM   5525 C  CA  . VAL   C 1 151 ? 17.626  -36.057 10.954  1.00 30.45  ? 137 VAL   L CA  1 
ATOM   5526 C  C   . VAL   C 1 151 ? 16.541  -35.093 10.471  1.00 31.51  ? 137 VAL   L C   1 
ATOM   5527 O  O   . VAL   C 1 151 ? 16.587  -33.904 10.818  1.00 31.44  ? 137 VAL   L O   1 
ATOM   5528 C  CB  . VAL   C 1 151 ? 17.224  -36.785 12.243  1.00 31.32  ? 137 VAL   L CB  1 
ATOM   5529 C  CG1 . VAL   C 1 151 ? 16.811  -35.785 13.301  1.00 36.22  ? 137 VAL   L CG1 1 
ATOM   5530 C  CG2 . VAL   C 1 151 ? 16.159  -37.819 11.989  1.00 32.79  ? 137 VAL   L CG2 1 
ATOM   5531 N  N   . HIS   C 1 152 ? 15.576  -35.606 9.707   1.00 29.90  ? 138 HIS   L N   1 
ATOM   5532 C  CA  . HIS   C 1 152 ? 14.416  -34.791 9.275   1.00 28.80  ? 138 HIS   L CA  1 
ATOM   5533 C  C   . HIS   C 1 152 ? 13.563  -34.466 10.512  1.00 29.93  ? 138 HIS   L C   1 
ATOM   5534 O  O   . HIS   C 1 152 ? 13.182  -35.383 11.248  1.00 29.77  ? 138 HIS   L O   1 
ATOM   5535 C  CB  . HIS   C 1 152 ? 13.589  -35.522 8.202   1.00 31.07  ? 138 HIS   L CB  1 
ATOM   5536 C  CG  . HIS   C 1 152 ? 12.684  -34.601 7.449   1.00 30.51  ? 138 HIS   L CG  1 
ATOM   5537 N  ND1 . HIS   C 1 152 ? 11.531  -34.086 8.024   1.00 30.81  ? 138 HIS   L ND1 1 
ATOM   5538 C  CD2 . HIS   C 1 152 ? 12.775  -34.082 6.209   1.00 33.81  ? 138 HIS   L CD2 1 
ATOM   5539 C  CE1 . HIS   C 1 152 ? 10.937  -33.279 7.150   1.00 34.42  ? 138 HIS   L CE1 1 
ATOM   5540 N  NE2 . HIS   C 1 152 ? 11.700  -33.236 6.017   1.00 33.70  ? 138 HIS   L NE2 1 
ATOM   5541 N  N   . GLU   C 1 153 ? 13.142  -33.221 10.661  1.00 29.78  ? 139 GLU   L N   1 
ATOM   5542 C  CA  . GLU   C 1 153 ? 12.342  -32.789 11.830  1.00 31.39  ? 139 GLU   L CA  1 
ATOM   5543 C  C   . GLU   C 1 153 ? 11.037  -33.600 11.919  1.00 29.89  ? 139 GLU   L C   1 
ATOM   5544 O  O   . GLU   C 1 153 ? 10.670  -33.947 13.021  1.00 30.28  ? 139 GLU   L O   1 
ATOM   5545 C  CB  . GLU   C 1 153 ? 12.117  -31.275 11.833  1.00 36.37  ? 139 GLU   L CB  1 
ATOM   5546 C  CG  . GLU   C 1 153 ? 11.000  -30.797 10.955  1.00 41.31  ? 139 GLU   L CG  1 
ATOM   5547 C  CD  . GLU   C 1 153 ? 10.714  -29.302 11.093  1.00 47.78  ? 139 GLU   L CD  1 
ATOM   5548 O  OE1 . GLU   C 1 153 ? 11.082  -28.809 12.184  1.00 49.95  ? 139 GLU   L OE1 1 
ATOM   5549 O  OE2 . GLU   C 1 153 ? 10.126  -28.629 10.094  1.00 38.91  ? 139 GLU   L OE2 1 
ATOM   5550 N  N   . ASP   C 1 154 ? 10.366  -33.921 10.825  1.00 29.24  ? 140 ASP   L N   1 
ATOM   5551 C  CA  . ASP   C 1 154 ? 9.068   -34.652 10.861  1.00 30.09  ? 140 ASP   L CA  1 
ATOM   5552 C  C   . ASP   C 1 154 ? 9.332   -36.116 11.274  1.00 30.82  ? 140 ASP   L C   1 
ATOM   5553 O  O   . ASP   C 1 154 ? 8.500   -36.709 11.973  1.00 29.09  ? 140 ASP   L O   1 
ATOM   5554 C  CB  . ASP   C 1 154 ? 8.305   -34.531 9.553   1.00 32.03  ? 140 ASP   L CB  1 
ATOM   5555 C  CG  . ASP   C 1 154 ? 7.826   -33.131 9.212   1.00 32.70  ? 140 ASP   L CG  1 
ATOM   5556 O  OD1 . ASP   C 1 154 ? 7.361   -32.441 10.138  1.00 34.00  ? 140 ASP   L OD1 1 
ATOM   5557 O  OD2 . ASP   C 1 154 ? 7.966   -32.723 8.025   1.00 32.49  ? 140 ASP   L OD2 1 
ATOM   5558 N  N   . GLU   C 1 155 ? 10.481  -36.676 10.901  1.00 30.32  ? 141 GLU   L N   1 
ATOM   5559 C  CA  . GLU   C 1 155 ? 10.848  -38.053 11.302  1.00 26.70  ? 141 GLU   L CA  1 
ATOM   5560 C  C   . GLU   C 1 155 ? 11.118  -38.073 12.811  1.00 28.83  ? 141 GLU   L C   1 
ATOM   5561 O  O   . GLU   C 1 155 ? 10.646  -38.978 13.497  1.00 30.58  ? 141 GLU   L O   1 
ATOM   5562 C  CB  . GLU   C 1 155 ? 12.044  -38.530 10.487  1.00 28.62  ? 141 GLU   L CB  1 
ATOM   5563 C  CG  . GLU   C 1 155 ? 12.362  -39.991 10.713  1.00 29.00  ? 141 GLU   L CG  1 
ATOM   5564 C  CD  . GLU   C 1 155 ? 11.369  -40.974 10.119  1.00 33.51  ? 141 GLU   L CD  1 
ATOM   5565 O  OE1 . GLU   C 1 155 ? 10.405  -40.522 9.449   1.00 32.87  ? 141 GLU   L OE1 1 
ATOM   5566 O  OE2 . GLU   C 1 155 ? 11.555  -42.193 10.308  1.00 34.44  ? 141 GLU   L OE2 1 
ATOM   5567 N  N   . PHE   C 1 156 ? 11.889  -37.125 13.295  1.00 28.23  ? 142 PHE   L N   1 
ATOM   5568 C  CA  . PHE   C 1 156 ? 12.212  -37.014 14.733  1.00 30.40  ? 142 PHE   L CA  1 
ATOM   5569 C  C   . PHE   C 1 156 ? 10.902  -36.889 15.518  1.00 32.96  ? 142 PHE   L C   1 
ATOM   5570 O  O   . PHE   C 1 156 ? 10.722  -37.600 16.523  1.00 31.48  ? 142 PHE   L O   1 
ATOM   5571 C  CB  . PHE   C 1 156 ? 13.157  -35.830 14.945  1.00 29.84  ? 142 PHE   L CB  1 
ATOM   5572 C  CG  . PHE   C 1 156 ? 13.848  -35.709 16.281  1.00 30.19  ? 142 PHE   L CG  1 
ATOM   5573 C  CD1 . PHE   C 1 156 ? 14.428  -36.827 16.870  1.00 33.37  ? 142 PHE   L CD1 1 
ATOM   5574 C  CD2 . PHE   C 1 156 ? 14.037  -34.478 16.874  1.00 31.54  ? 142 PHE   L CD2 1 
ATOM   5575 C  CE1 . PHE   C 1 156 ? 15.138  -36.716 18.047  1.00 37.96  ? 142 PHE   L CE1 1 
ATOM   5576 C  CE2 . PHE   C 1 156 ? 14.714  -34.379 18.078  1.00 34.43  ? 142 PHE   L CE2 1 
ATOM   5577 C  CZ  . PHE   C 1 156 ? 15.306  -35.493 18.629  1.00 34.04  ? 142 PHE   L CZ  1 
ATOM   5578 N  N   . ASN   C 1 157 ? 10.007  -35.970 15.108  1.00 30.63  ? 143 ASN   L N   1 
ATOM   5579 C  CA  . ASN   C 1 157 ? 8.750   -35.736 15.855  1.00 30.18  ? 143 ASN   L CA  1 
ATOM   5580 C  C   . ASN   C 1 157 ? 7.967   -37.038 15.928  1.00 32.84  ? 143 ASN   L C   1 
ATOM   5581 O  O   . ASN   C 1 157 ? 7.400   -37.342 17.014  1.00 33.21  ? 143 ASN   L O   1 
ATOM   5582 C  CB  . ASN   C 1 157 ? 7.898   -34.613 15.253  1.00 31.94  ? 143 ASN   L CB  1 
ATOM   5583 C  CG  . ASN   C 1 157 ? 8.557   -33.266 15.409  1.00 33.64  ? 143 ASN   L CG  1 
ATOM   5584 O  OD1 . ASN   C 1 157 ? 9.448   -33.096 16.230  1.00 37.80  ? 143 ASN   L OD1 1 
ATOM   5585 N  ND2 . ASN   C 1 157 ? 8.109   -32.280 14.654  1.00 36.84  ? 143 ASN   L ND2 1 
ATOM   5586 N  N   . GLY   C 1 158 ? 7.864   -37.758 14.818  1.00 30.23  ? 144 GLY   L N   1 
ATOM   5587 C  CA  . GLY   C 1 158 ? 7.043   -38.971 14.736  1.00 31.41  ? 144 GLY   L CA  1 
ATOM   5588 C  C   . GLY   C 1 158 ? 7.619   -40.061 15.623  1.00 33.61  ? 144 GLY   L C   1 
ATOM   5589 O  O   . GLY   C 1 158 ? 6.855   -40.733 16.353  1.00 34.52  ? 144 GLY   L O   1 
ATOM   5590 N  N   . ALA   C 1 159 ? 8.930   -40.208 15.641  1.00 32.44  ? 145 ALA   L N   1 
ATOM   5591 C  CA  . ALA   C 1 159 ? 9.572   -41.246 16.487  1.00 33.67  ? 145 ALA   L CA  1 
ATOM   5592 C  C   . ALA   C 1 159 ? 9.365   -40.877 17.967  1.00 32.15  ? 145 ALA   L C   1 
ATOM   5593 O  O   . ALA   C 1 159 ? 9.023   -41.719 18.807  1.00 32.74  ? 145 ALA   L O   1 
ATOM   5594 C  CB  . ALA   C 1 159 ? 11.030  -41.349 16.119  1.00 33.67  ? 145 ALA   L CB  1 
ATOM   5595 N  N   . LEU   C 1 160 ? 9.617   -39.635 18.311  1.00 30.61  ? 146 LEU   L N   1 
ATOM   5596 C  CA  . LEU   C 1 160 ? 9.412   -39.168 19.695  1.00 31.61  ? 146 LEU   L CA  1 
ATOM   5597 C  C   . LEU   C 1 160 ? 7.954   -39.381 20.124  1.00 35.73  ? 146 LEU   L C   1 
ATOM   5598 O  O   . LEU   C 1 160 ? 7.759   -39.738 21.302  1.00 32.77  ? 146 LEU   L O   1 
ATOM   5599 C  CB  . LEU   C 1 160 ? 9.833   -37.702 19.841  1.00 31.69  ? 146 LEU   L CB  1 
ATOM   5600 C  CG  . LEU   C 1 160 ? 11.311  -37.389 19.675  1.00 30.48  ? 146 LEU   L CG  1 
ATOM   5601 C  CD1 . LEU   C 1 160 ? 11.576  -35.920 19.846  1.00 33.38  ? 146 LEU   L CD1 1 
ATOM   5602 C  CD2 . LEU   C 1 160 ? 12.190  -38.166 20.637  1.00 36.71  ? 146 LEU   L CD2 1 
ATOM   5603 N  N   . GLN   C 1 161 ? 6.951   -39.188 19.262  1.00 32.45  ? 147 GLN   L N   1 
ATOM   5604 C  CA  . GLN   C 1 161 ? 5.546   -39.512 19.638  1.00 34.70  ? 147 GLN   L CA  1 
ATOM   5605 C  C   . GLN   C 1 161 ? 5.394   -41.029 19.899  1.00 35.63  ? 147 GLN   L C   1 
ATOM   5606 O  O   . GLN   C 1 161 ? 4.650   -41.420 20.841  1.00 34.35  ? 147 GLN   L O   1 
ATOM   5607 C  CB  . GLN   C 1 161 ? 4.512   -39.051 18.604  1.00 32.16  ? 147 GLN   L CB  1 
ATOM   5608 C  CG  . GLN   C 1 161 ? 4.246   -37.539 18.616  1.00 35.51  ? 147 GLN   L CG  1 
ATOM   5609 C  CD  . GLN   C 1 161 ? 2.921   -37.222 17.959  1.00 37.95  ? 147 GLN   L CD  1 
ATOM   5610 O  OE1 . GLN   C 1 161 ? 1.980   -38.008 18.053  1.00 37.25  ? 147 GLN   L OE1 1 
ATOM   5611 N  NE2 . GLN   C 1 161 ? 2.844   -36.092 17.270  1.00 36.37  ? 147 GLN   L NE2 1 
ATOM   5612 N  N   . CYS   C 1 162 ? 6.015   -41.888 19.103  1.00 33.75  ? 148 CYS   L N   1 
ATOM   5613 C  CA  . CYS   C 1 162 ? 5.975   -43.358 19.356  1.00 35.91  ? 148 CYS   L CA  1 
ATOM   5614 C  C   . CYS   C 1 162 ? 6.477   -43.642 20.774  1.00 35.87  ? 148 CYS   L C   1 
ATOM   5615 O  O   . CYS   C 1 162 ? 5.825   -44.433 21.448  1.00 37.49  ? 148 CYS   L O   1 
ATOM   5616 C  CB  . CYS   C 1 162 ? 6.816   -44.136 18.370  1.00 34.86  ? 148 CYS   L CB  1 
ATOM   5617 S  SG  . CYS   C 1 162 ? 6.111   -44.106 16.711  1.00 39.85  ? 148 CYS   L SG  1 
ATOM   5618 N  N   . TYR   C 1 163 ? 7.571   -43.000 21.174  1.00 34.59  ? 149 TYR   L N   1 
ATOM   5619 C  CA  . TYR   C 1 163 ? 8.234   -43.154 22.484  1.00 36.75  ? 149 TYR   L CA  1 
ATOM   5620 C  C   . TYR   C 1 163 ? 7.288   -42.660 23.576  1.00 36.49  ? 149 TYR   L C   1 
ATOM   5621 O  O   . TYR   C 1 163 ? 7.060   -43.397 24.550  1.00 35.95  ? 149 TYR   L O   1 
ATOM   5622 C  CB  . TYR   C 1 163 ? 9.554   -42.388 22.544  1.00 36.47  ? 149 TYR   L CB  1 
ATOM   5623 C  CG  . TYR   C 1 163 ? 10.293  -42.507 23.851  1.00 37.39  ? 149 TYR   L CG  1 
ATOM   5624 C  CD1 . TYR   C 1 163 ? 10.996  -43.658 24.162  1.00 39.75  ? 149 TYR   L CD1 1 
ATOM   5625 C  CD2 . TYR   C 1 163 ? 10.287  -41.480 24.786  1.00 39.90  ? 149 TYR   L CD2 1 
ATOM   5626 C  CE1 . TYR   C 1 163 ? 11.651  -43.803 25.379  1.00 41.87  ? 149 TYR   L CE1 1 
ATOM   5627 C  CE2 . TYR   C 1 163 ? 10.933  -41.613 26.010  1.00 42.22  ? 149 TYR   L CE2 1 
ATOM   5628 C  CZ  . TYR   C 1 163 ? 11.641  -42.773 26.297  1.00 43.09  ? 149 TYR   L CZ  1 
ATOM   5629 O  OH  . TYR   C 1 163 ? 12.331  -42.895 27.472  1.00 43.94  ? 149 TYR   L OH  1 
ATOM   5630 N  N   . ALA   C 1 164 ? 6.754   -41.446 23.407  1.00 32.75  ? 150 ALA   L N   1 
ATOM   5631 C  CA  . ALA   C 1 164 ? 5.877   -40.785 24.396  1.00 35.77  ? 150 ALA   L CA  1 
ATOM   5632 C  C   . ALA   C 1 164 ? 4.596   -41.577 24.608  1.00 37.35  ? 150 ALA   L C   1 
ATOM   5633 O  O   . ALA   C 1 164 ? 4.133   -41.578 25.731  1.00 36.55  ? 150 ALA   L O   1 
ATOM   5634 C  CB  . ALA   C 1 164 ? 5.546   -39.369 24.007  1.00 37.11  ? 150 ALA   L CB  1 
ATOM   5635 N  N   . ARG   C 1 165 ? 4.080   -42.243 23.578  1.00 34.37  ? 151 ARG   L N   1 
ATOM   5636 C  CA  . ARG   C 1 165 ? 2.844   -43.051 23.637  1.00 40.31  ? 151 ARG   L CA  1 
ATOM   5637 C  C   . ARG   C 1 165 ? 3.195   -44.470 24.077  1.00 38.82  ? 151 ARG   L C   1 
ATOM   5638 O  O   . ARG   C 1 165 ? 2.301   -45.278 24.062  1.00 40.79  ? 151 ARG   L O   1 
ATOM   5639 C  CB  . ARG   C 1 165 ? 2.127   -43.102 22.280  1.00 41.87  ? 151 ARG   L CB  1 
ATOM   5640 C  CG  . ARG   C 1 165 ? 1.627   -41.744 21.786  1.00 44.19  ? 151 ARG   L CG  1 
ATOM   5641 C  CD  . ARG   C 1 165 ? 1.210   -41.772 20.315  1.00 44.64  ? 151 ARG   L CD  1 
ATOM   5642 N  NE  . ARG   C 1 165 ? 0.832   -40.461 19.739  1.00 46.28  ? 151 ARG   L NE  1 
ATOM   5643 C  CZ  . ARG   C 1 165 ? -0.409  -39.959 19.758  1.00 47.95  ? 151 ARG   L CZ  1 
ATOM   5644 N  NH1 . ARG   C 1 165 ? -1.376  -40.622 20.356  1.00 49.15  ? 151 ARG   L NH1 1 
ATOM   5645 N  NH2 . ARG   C 1 165 ? -0.696  -38.800 19.195  1.00 44.79  ? 151 ARG   L NH2 1 
ATOM   5646 N  N   . ASN   C 1 166 ? 4.458   -44.767 24.383  1.00 39.66  ? 152 ASN   L N   1 
ATOM   5647 C  CA  . ASN   C 1 166 ? 4.869   -46.119 24.847  1.00 43.27  ? 152 ASN   L CA  1 
ATOM   5648 C  C   . ASN   C 1 166 ? 4.502   -47.161 23.784  1.00 45.77  ? 152 ASN   L C   1 
ATOM   5649 O  O   . ASN   C 1 166 ? 3.997   -48.226 24.155  1.00 46.31  ? 152 ASN   L O   1 
ATOM   5650 C  CB  . ASN   C 1 166 ? 4.280   -46.431 26.239  1.00 46.37  ? 152 ASN   L CB  1 
ATOM   5651 C  CG  . ASN   C 1 166 ? 4.977   -45.611 27.304  1.00 47.28  ? 152 ASN   L CG  1 
ATOM   5652 O  OD1 . ASN   C 1 166 ? 6.171   -45.780 27.543  1.00 43.04  ? 152 ASN   L OD1 1 
ATOM   5653 N  ND2 . ASN   C 1 166 ? 4.285   -44.636 27.875  1.00 48.05  ? 152 ASN   L ND2 1 
ATOM   5654 N  N   . GLN   C 1 167 ? 4.693   -46.876 22.492  1.00 40.68  ? 153 GLN   L N   1 
ATOM   5655 C  CA  . GLN   C 1 167 ? 4.418   -47.911 21.452  1.00 43.96  ? 153 GLN   L CA  1 
ATOM   5656 C  C   . GLN   C 1 167 ? 5.571   -48.924 21.474  1.00 44.76  ? 153 GLN   L C   1 
ATOM   5657 O  O   . GLN   C 1 167 ? 6.726   -48.509 21.292  1.00 47.54  ? 153 GLN   L O   1 
ATOM   5658 C  CB  . GLN   C 1 167 ? 4.228   -47.303 20.067  1.00 50.53  ? 153 GLN   L CB  1 
ATOM   5659 C  CG  . GLN   C 1 167 ? 2.897   -46.570 19.978  1.00 75.82  ? 153 GLN   L CG  1 
ATOM   5660 C  CD  . GLN   C 1 167 ? 2.405   -46.334 18.572  1.00 87.88  ? 153 GLN   L CD  1 
ATOM   5661 O  OE1 . GLN   C 1 167 ? 1.803   -47.210 17.954  1.00 100.07 ? 153 GLN   L OE1 1 
ATOM   5662 N  NE2 . GLN   C 1 167 ? 2.639   -45.133 18.067  1.00 72.64  ? 153 GLN   L NE2 1 
ATOM   5663 N  N   . LYS   C 1 168 ? 5.268   -50.198 21.676  1.00 52.11  ? 154 LYS   L N   1 
ATOM   5664 C  CA  . LYS   C 1 168 ? 6.260   -51.303 21.831  1.00 57.40  ? 154 LYS   L CA  1 
ATOM   5665 C  C   . LYS   C 1 168 ? 6.455   -52.106 20.547  1.00 54.40  ? 154 LYS   L C   1 
ATOM   5666 O  O   . LYS   C 1 168 ? 7.509   -52.744 20.432  1.00 59.75  ? 154 LYS   L O   1 
ATOM   5667 C  CB  . LYS   C 1 168 ? 5.811   -52.240 22.953  1.00 63.21  ? 154 LYS   L CB  1 
ATOM   5668 C  CG  . LYS   C 1 168 ? 6.053   -51.691 24.353  1.00 66.34  ? 154 LYS   L CG  1 
ATOM   5669 C  CD  . LYS   C 1 168 ? 7.331   -50.867 24.487  1.00 64.32  ? 154 LYS   L CD  1 
ATOM   5670 C  CE  . LYS   C 1 168 ? 7.895   -50.811 25.889  1.00 71.38  ? 154 LYS   L CE  1 
ATOM   5671 N  NZ  . LYS   C 1 168 ? 7.418   -49.611 26.621  1.00 73.70  ? 154 LYS   L NZ  1 
ATOM   5672 N  N   . GLU   C 1 169 ? 5.486   -52.078 19.636  1.00 50.28  ? 155 GLU   L N   1 
ATOM   5673 C  CA  . GLU   C 1 169 ? 5.523   -52.828 18.361  1.00 56.63  ? 155 GLU   L CA  1 
ATOM   5674 C  C   . GLU   C 1 169 ? 5.815   -51.847 17.227  1.00 55.88  ? 155 GLU   L C   1 
ATOM   5675 O  O   . GLU   C 1 169 ? 5.873   -50.634 17.495  1.00 59.35  ? 155 GLU   L O   1 
ATOM   5676 C  CB  . GLU   C 1 169 ? 4.186   -53.512 18.122  1.00 62.02  ? 155 GLU   L CB  1 
ATOM   5677 C  CG  . GLU   C 1 169 ? 3.692   -54.246 19.351  1.00 75.03  ? 155 GLU   L CG  1 
ATOM   5678 C  CD  . GLU   C 1 169 ? 3.024   -55.567 19.037  1.00 81.67  ? 155 GLU   L CD  1 
ATOM   5679 O  OE1 . GLU   C 1 169 ? 1.781   -55.573 18.886  1.00 90.13  ? 155 GLU   L OE1 1 
ATOM   5680 O  OE2 . GLU   C 1 169 ? 3.751   -56.576 18.929  1.00 76.53  ? 155 GLU   L OE2 1 
ATOM   5681 N  N   . GLY   C 1 170 ? 6.007   -52.365 16.022  1.00 49.61  ? 156 GLY   L N   1 
ATOM   5682 C  CA  . GLY   C 1 170 ? 6.289   -51.554 14.828  1.00 50.73  ? 156 GLY   L CA  1 
ATOM   5683 C  C   . GLY   C 1 170 ? 7.760   -51.209 14.670  1.00 48.14  ? 156 GLY   L C   1 
ATOM   5684 O  O   . GLY   C 1 170 ? 8.643   -51.797 15.369  1.00 43.97  ? 156 GLY   L O   1 
ATOM   5685 N  N   . ALA   C 1 171 ? 8.013   -50.297 13.729  1.00 42.70  ? 157 ALA   L N   1 
ATOM   5686 C  CA  . ALA   C 1 171 ? 9.319   -50.100 13.082  1.00 44.40  ? 157 ALA   L CA  1 
ATOM   5687 C  C   . ALA   C 1 171 ? 10.133  -49.042 13.834  1.00 38.01  ? 157 ALA   L C   1 
ATOM   5688 O  O   . ALA   C 1 171 ? 11.316  -48.862 13.434  1.00 41.86  ? 157 ALA   L O   1 
ATOM   5689 C  CB  . ALA   C 1 171 ? 9.094   -49.760 11.620  1.00 44.75  ? 157 ALA   L CB  1 
ATOM   5690 N  N   . TYR   C 1 172 ? 9.567   -48.409 14.879  1.00 33.60  ? 158 TYR   L N   1 
ATOM   5691 C  CA  . TYR   C 1 172 ? 10.254  -47.403 15.723  1.00 35.58  ? 158 TYR   L CA  1 
ATOM   5692 C  C   . TYR   C 1 172 ? 10.513  -48.069 17.084  1.00 37.11  ? 158 TYR   L C   1 
ATOM   5693 O  O   . TYR   C 1 172 ? 9.530   -48.401 17.771  1.00 40.53  ? 158 TYR   L O   1 
ATOM   5694 C  CB  . TYR   C 1 172 ? 9.447   -46.084 15.781  1.00 34.37  ? 158 TYR   L CB  1 
ATOM   5695 C  CG  . TYR   C 1 172 ? 9.403   -45.415 14.428  1.00 33.63  ? 158 TYR   L CG  1 
ATOM   5696 C  CD1 . TYR   C 1 172 ? 10.462  -44.633 13.994  1.00 31.81  ? 158 TYR   L CD1 1 
ATOM   5697 C  CD2 . TYR   C 1 172 ? 8.351   -45.632 13.555  1.00 33.88  ? 158 TYR   L CD2 1 
ATOM   5698 C  CE1 . TYR   C 1 172 ? 10.485  -44.081 12.717  1.00 34.29  ? 158 TYR   L CE1 1 
ATOM   5699 C  CE2 . TYR   C 1 172 ? 8.356   -45.083 12.267  1.00 36.44  ? 158 TYR   L CE2 1 
ATOM   5700 C  CZ  . TYR   C 1 172 ? 9.421   -44.285 11.854  1.00 32.68  ? 158 TYR   L CZ  1 
ATOM   5701 O  OH  . TYR   C 1 172 ? 9.451   -43.741 10.595  1.00 33.86  ? 158 TYR   L OH  1 
ATOM   5702 N  N   . ILE   C 1 173 ? 11.773  -48.314 17.428  1.00 35.68  ? 159 ILE   L N   1 
ATOM   5703 C  CA  . ILE   C 1 173 ? 12.120  -49.220 18.572  1.00 34.16  ? 159 ILE   L CA  1 
ATOM   5704 C  C   . ILE   C 1 173 ? 12.255  -48.407 19.862  1.00 33.08  ? 159 ILE   L C   1 
ATOM   5705 O  O   . ILE   C 1 173 ? 13.181  -47.573 19.978  1.00 33.79  ? 159 ILE   L O   1 
ATOM   5706 C  CB  . ILE   C 1 173 ? 13.406  -50.013 18.276  1.00 33.77  ? 159 ILE   L CB  1 
ATOM   5707 C  CG1 . ILE   C 1 173 ? 13.307  -50.810 16.974  1.00 35.61  ? 159 ILE   L CG1 1 
ATOM   5708 C  CG2 . ILE   C 1 173 ? 13.738  -50.877 19.492  1.00 37.18  ? 159 ILE   L CG2 1 
ATOM   5709 C  CD1 . ILE   C 1 173 ? 12.105  -51.729 16.906  1.00 39.71  ? 159 ILE   L CD1 1 
ATOM   5710 N  N   . TRP   C 1 174 ? 11.340  -48.615 20.796  1.00 35.32  ? 160 TRP   L N   1 
ATOM   5711 C  CA  . TRP   C 1 174 ? 11.216  -47.825 22.053  1.00 37.42  ? 160 TRP   L CA  1 
ATOM   5712 C  C   . TRP   C 1 174 ? 12.567  -47.761 22.777  1.00 34.56  ? 160 TRP   L C   1 
ATOM   5713 O  O   . TRP   C 1 174 ? 12.995  -46.634 23.208  1.00 34.58  ? 160 TRP   L O   1 
ATOM   5714 C  CB  . TRP   C 1 174 ? 10.099  -48.432 22.938  1.00 38.40  ? 160 TRP   L CB  1 
ATOM   5715 C  CG  . TRP   C 1 174 ? 9.665   -47.492 24.014  1.00 38.64  ? 160 TRP   L CG  1 
ATOM   5716 C  CD1 . TRP   C 1 174 ? 8.684   -46.550 23.904  1.00 42.98  ? 160 TRP   L CD1 1 
ATOM   5717 C  CD2 . TRP   C 1 174 ? 10.228  -47.342 25.331  1.00 42.57  ? 160 TRP   L CD2 1 
ATOM   5718 N  NE1 . TRP   C 1 174 ? 8.602   -45.829 25.059  1.00 39.30  ? 160 TRP   L NE1 1 
ATOM   5719 C  CE2 . TRP   C 1 174 ? 9.525   -46.289 25.957  1.00 41.62  ? 160 TRP   L CE2 1 
ATOM   5720 C  CE3 . TRP   C 1 174 ? 11.249  -47.986 26.050  1.00 42.36  ? 160 TRP   L CE3 1 
ATOM   5721 C  CZ2 . TRP   C 1 174 ? 9.821   -45.852 27.255  1.00 42.31  ? 160 TRP   L CZ2 1 
ATOM   5722 C  CZ3 . TRP   C 1 174 ? 11.544  -47.553 27.324  1.00 46.54  ? 160 TRP   L CZ3 1 
ATOM   5723 C  CH2 . TRP   C 1 174 ? 10.835  -46.501 27.922  1.00 46.75  ? 160 TRP   L CH2 1 
ATOM   5724 N  N   . ALA   C 1 175 ? 13.225  -48.933 22.925  1.00 37.22  ? 161 ALA   L N   1 
ATOM   5725 C  CA  . ALA   C 1 175 ? 14.491  -49.102 23.673  1.00 38.98  ? 161 ALA   L CA  1 
ATOM   5726 C  C   . ALA   C 1 175 ? 15.616  -48.387 22.932  1.00 36.15  ? 161 ALA   L C   1 
ATOM   5727 O  O   . ALA   C 1 175 ? 16.491  -47.806 23.623  1.00 37.19  ? 161 ALA   L O   1 
ATOM   5728 C  CB  . ALA   C 1 175 ? 14.784  -50.583 23.935  1.00 39.41  ? 161 ALA   L CB  1 
ATOM   5729 N  N   . ASP   C 1 176 ? 15.563  -48.296 21.584  1.00 35.13  ? 162 ASP   L N   1 
ATOM   5730 C  CA  . ASP   C 1 176 ? 16.565  -47.503 20.821  1.00 32.11  ? 162 ASP   L CA  1 
ATOM   5731 C  C   . ASP   C 1 176 ? 16.383  -46.015 21.173  1.00 35.30  ? 162 ASP   L C   1 
ATOM   5732 O  O   . ASP   C 1 176 ? 17.383  -45.310 21.517  1.00 31.38  ? 162 ASP   L O   1 
ATOM   5733 C  CB  . ASP   C 1 176 ? 16.502  -47.792 19.311  1.00 33.96  ? 162 ASP   L CB  1 
ATOM   5734 C  CG  . ASP   C 1 176 ? 17.003  -49.177 18.871  1.00 41.61  ? 162 ASP   L CG  1 
ATOM   5735 O  OD1 . ASP   C 1 176 ? 17.456  -49.955 19.748  1.00 41.71  ? 162 ASP   L OD1 1 
ATOM   5736 O  OD2 . ASP   C 1 176 ? 16.944  -49.501 17.635  1.00 38.52  ? 162 ASP   L OD2 1 
ATOM   5737 N  N   . ILE   C 1 177 ? 15.128  -45.536 21.143  1.00 39.78  ? 163 ILE   L N   1 
ATOM   5738 C  CA  . ILE   C 1 177 ? 14.844  -44.089 21.367  1.00 36.44  ? 163 ILE   L CA  1 
ATOM   5739 C  C   . ILE   C 1 177 ? 15.221  -43.756 22.813  1.00 32.80  ? 163 ILE   L C   1 
ATOM   5740 O  O   . ILE   C 1 177 ? 15.859  -42.710 23.057  1.00 31.75  ? 163 ILE   L O   1 
ATOM   5741 C  CB  . ILE   C 1 177 ? 13.378  -43.746 21.013  1.00 35.29  ? 163 ILE   L CB  1 
ATOM   5742 C  CG1 . ILE   C 1 177 ? 13.038  -44.081 19.561  1.00 35.49  ? 163 ILE   L CG1 1 
ATOM   5743 C  CG2 . ILE   C 1 177 ? 13.107  -42.275 21.299  1.00 34.21  ? 163 ILE   L CG2 1 
ATOM   5744 C  CD1 . ILE   C 1 177 ? 11.566  -44.345 19.305  1.00 36.29  ? 163 ILE   L CD1 1 
ATOM   5745 N  N   . ASP   C 1 178 ? 14.849  -44.649 23.736  1.00 36.94  ? 164 ASP   L N   1 
ATOM   5746 C  CA  . ASP   C 1 178 ? 15.228  -44.539 25.163  1.00 38.24  ? 164 ASP   L CA  1 
ATOM   5747 C  C   . ASP   C 1 178 ? 16.738  -44.293 25.254  1.00 37.62  ? 164 ASP   L C   1 
ATOM   5748 O  O   . ASP   C 1 178 ? 17.156  -43.334 25.958  1.00 35.65  ? 164 ASP   L O   1 
ATOM   5749 C  CB  . ASP   C 1 178 ? 14.764  -45.772 25.950  1.00 38.60  ? 164 ASP   L CB  1 
ATOM   5750 C  CG  . ASP   C 1 178 ? 14.774  -45.547 27.460  1.00 50.76  ? 164 ASP   L CG  1 
ATOM   5751 O  OD1 . ASP   C 1 178 ? 14.202  -44.549 27.914  1.00 43.91  ? 164 ASP   L OD1 1 
ATOM   5752 O  OD2 . ASP   C 1 178 ? 15.438  -46.308 28.153  1.00 47.04  ? 164 ASP   L OD2 1 
ATOM   5753 N  N   . ALA   C 1 179 ? 17.560  -45.082 24.543  1.00 41.27  ? 165 ALA   L N   1 
ATOM   5754 C  CA  . ALA   C 1 179 ? 19.037  -44.923 24.603  1.00 39.80  ? 165 ALA   L CA  1 
ATOM   5755 C  C   . ALA   C 1 179 ? 19.476  -43.591 23.971  1.00 35.62  ? 165 ALA   L C   1 
ATOM   5756 O  O   . ALA   C 1 179 ? 20.436  -42.942 24.481  1.00 38.42  ? 165 ALA   L O   1 
ATOM   5757 C  CB  . ALA   C 1 179 ? 19.718  -46.135 23.990  1.00 38.93  ? 165 ALA   L CB  1 
ATOM   5758 N  N   . TRP   C 1 180 ? 18.837  -43.120 22.899  1.00 39.25  ? 166 TRP   L N   1 
ATOM   5759 C  CA  . TRP   C 1 180 ? 19.266  -41.825 22.280  1.00 40.06  ? 166 TRP   L CA  1 
ATOM   5760 C  C   . TRP   C 1 180 ? 19.155  -40.710 23.307  1.00 38.13  ? 166 TRP   L C   1 
ATOM   5761 O  O   . TRP   C 1 180 ? 20.018  -39.806 23.307  1.00 43.06  ? 166 TRP   L O   1 
ATOM   5762 C  CB  . TRP   C 1 180 ? 18.459  -41.448 21.033  1.00 38.48  ? 166 TRP   L CB  1 
ATOM   5763 C  CG  . TRP   C 1 180 ? 18.351  -42.533 20.018  1.00 36.44  ? 166 TRP   L CG  1 
ATOM   5764 C  CD1 . TRP   C 1 180 ? 19.188  -43.612 19.869  1.00 38.11  ? 166 TRP   L CD1 1 
ATOM   5765 C  CD2 . TRP   C 1 180 ? 17.347  -42.635 18.996  1.00 37.39  ? 166 TRP   L CD2 1 
ATOM   5766 N  NE1 . TRP   C 1 180 ? 18.728  -44.413 18.862  1.00 38.76  ? 166 TRP   L NE1 1 
ATOM   5767 C  CE2 . TRP   C 1 180 ? 17.602  -43.838 18.307  1.00 40.21  ? 166 TRP   L CE2 1 
ATOM   5768 C  CE3 . TRP   C 1 180 ? 16.254  -41.831 18.613  1.00 38.11  ? 166 TRP   L CE3 1 
ATOM   5769 C  CZ2 . TRP   C 1 180 ? 16.791  -44.273 17.254  1.00 39.83  ? 166 TRP   L CZ2 1 
ATOM   5770 C  CZ3 . TRP   C 1 180 ? 15.460  -42.267 17.575  1.00 37.40  ? 166 TRP   L CZ3 1 
ATOM   5771 C  CH2 . TRP   C 1 180 ? 15.721  -43.471 16.914  1.00 39.36  ? 166 TRP   L CH2 1 
ATOM   5772 N  N   . ILE   C 1 181 ? 18.064  -40.713 24.073  1.00 39.83  ? 167 ILE   L N   1 
ATOM   5773 C  CA  . ILE   C 1 181 ? 17.806  -39.627 25.061  1.00 42.00  ? 167 ILE   L CA  1 
ATOM   5774 C  C   . ILE   C 1 181 ? 18.772  -39.805 26.251  1.00 40.64  ? 167 ILE   L C   1 
ATOM   5775 O  O   . ILE   C 1 181 ? 19.463  -38.834 26.631  1.00 42.33  ? 167 ILE   L O   1 
ATOM   5776 C  CB  . ILE   C 1 181 ? 16.330  -39.657 25.489  1.00 42.20  ? 167 ILE   L CB  1 
ATOM   5777 C  CG1 . ILE   C 1 181 ? 15.397  -39.504 24.288  1.00 39.66  ? 167 ILE   L CG1 1 
ATOM   5778 C  CG2 . ILE   C 1 181 ? 16.062  -38.619 26.578  1.00 42.21  ? 167 ILE   L CG2 1 
ATOM   5779 C  CD1 . ILE   C 1 181 ? 13.961  -39.780 24.607  1.00 46.08  ? 167 ILE   L CD1 1 
ATOM   5780 N  N   . LYS   C 1 182 ? 18.879  -41.016 26.793  1.00 42.06  ? 168 LYS   L N   1 
ATOM   5781 C  CA  . LYS   C 1 182 ? 19.814  -41.261 27.936  1.00 43.04  ? 168 LYS   L CA  1 
ATOM   5782 C  C   . LYS   C 1 182 ? 21.258  -40.906 27.566  1.00 46.11  ? 168 LYS   L C   1 
ATOM   5783 O  O   . LYS   C 1 182 ? 21.963  -40.383 28.439  1.00 41.71  ? 168 LYS   L O   1 
ATOM   5784 C  CB  . LYS   C 1 182 ? 19.672  -42.703 28.399  1.00 51.99  ? 168 LYS   L CB  1 
ATOM   5785 C  CG  . LYS   C 1 182 ? 18.398  -42.920 29.192  1.00 54.94  ? 168 LYS   L CG  1 
ATOM   5786 C  CD  . LYS   C 1 182 ? 18.202  -44.319 29.649  1.00 64.58  ? 168 LYS   L CD  1 
ATOM   5787 C  CE  . LYS   C 1 182 ? 16.891  -44.460 30.396  1.00 67.72  ? 168 LYS   L CE  1 
ATOM   5788 N  NZ  . LYS   C 1 182 ? 16.543  -45.889 30.547  1.00 75.50  ? 168 LYS   L NZ  1 
ATOM   5789 N  N   . ASN   C 1 183 ? 21.680  -41.107 26.308  1.00 42.31  ? 169 ASN   L N   1 
ATOM   5790 C  CA  . ASN   C 1 183 ? 23.081  -40.857 25.887  1.00 42.25  ? 169 ASN   L CA  1 
ATOM   5791 C  C   . ASN   C 1 183 ? 23.268  -39.409 25.472  1.00 40.56  ? 169 ASN   L C   1 
ATOM   5792 O  O   . ASN   C 1 183 ? 24.376  -39.079 25.104  1.00 37.81  ? 169 ASN   L O   1 
ATOM   5793 C  CB  . ASN   C 1 183 ? 23.538  -41.827 24.799  1.00 45.01  ? 169 ASN   L CB  1 
ATOM   5794 C  CG  . ASN   C 1 183 ? 23.694  -43.240 25.330  1.00 46.27  ? 169 ASN   L CG  1 
ATOM   5795 O  OD1 . ASN   C 1 183 ? 23.208  -43.571 26.388  1.00 52.77  ? 169 ASN   L OD1 1 
ATOM   5796 N  ND2 . ASN   C 1 183 ? 24.285  -44.117 24.561  1.00 61.49  ? 169 ASN   L ND2 1 
ATOM   5797 N  N   . ASN   C 1 184 ? 22.224  -38.575 25.504  1.00 41.03  ? 170 ASN   L N   1 
ATOM   5798 C  CA  . ASN   C 1 184 ? 22.353  -37.111 25.293  1.00 38.05  ? 170 ASN   L CA  1 
ATOM   5799 C  C   . ASN   C 1 184 ? 22.926  -36.807 23.890  1.00 35.95  ? 170 ASN   L C   1 
ATOM   5800 O  O   . ASN   C 1 184 ? 23.822  -35.963 23.733  1.00 39.37  ? 170 ASN   L O   1 
ATOM   5801 C  CB  . ASN   C 1 184 ? 23.214  -36.502 26.400  1.00 42.95  ? 170 ASN   L CB  1 
ATOM   5802 C  CG  . ASN   C 1 184 ? 23.031  -35.008 26.465  1.00 49.42  ? 170 ASN   L CG  1 
ATOM   5803 O  OD1 . ASN   C 1 184 ? 21.951  -34.492 26.194  1.00 52.89  ? 170 ASN   L OD1 1 
ATOM   5804 N  ND2 . ASN   C 1 184 ? 24.102  -34.303 26.746  1.00 52.33  ? 170 ASN   L ND2 1 
ATOM   5805 N  N   . LEU   C 1 185 ? 22.384  -37.442 22.869  1.00 38.05  ? 171 LEU   L N   1 
ATOM   5806 C  CA  . LEU   C 1 185 ? 22.783  -37.172 21.465  1.00 36.02  ? 171 LEU   L CA  1 
ATOM   5807 C  C   . LEU   C 1 185 ? 22.512  -35.713 21.143  1.00 41.04  ? 171 LEU   L C   1 
ATOM   5808 O  O   . LEU   C 1 185 ? 21.593  -35.103 21.748  1.00 36.14  ? 171 LEU   L O   1 
ATOM   5809 C  CB  . LEU   C 1 185 ? 22.052  -38.120 20.527  1.00 36.88  ? 171 LEU   L CB  1 
ATOM   5810 C  CG  . LEU   C 1 185 ? 22.362  -39.602 20.767  1.00 38.40  ? 171 LEU   L CG  1 
ATOM   5811 C  CD1 . LEU   C 1 185 ? 21.702  -40.476 19.724  1.00 35.46  ? 171 LEU   L CD1 1 
ATOM   5812 C  CD2 . LEU   C 1 185 ? 23.868  -39.824 20.770  1.00 39.50  ? 171 LEU   L CD2 1 
ATOM   5813 N  N   . GLN   C 1 186 ? 23.329  -35.169 20.257  1.00 36.52  ? 172 GLN   L N   1 
ATOM   5814 C  CA  . GLN   C 1 186 ? 23.219  -33.765 19.791  1.00 40.99  ? 172 GLN   L CA  1 
ATOM   5815 C  C   . GLN   C 1 186 ? 22.536  -33.763 18.408  1.00 42.34  ? 172 GLN   L C   1 
ATOM   5816 O  O   . GLN   C 1 186 ? 23.139  -34.214 17.412  1.00 39.81  ? 172 GLN   L O   1 
ATOM   5817 C  CB  . GLN   C 1 186 ? 24.607  -33.119 19.774  1.00 42.01  ? 172 GLN   L CB  1 
ATOM   5818 C  CG  . GLN   C 1 186 ? 25.271  -33.122 21.162  1.00 46.76  ? 172 GLN   L CG  1 
ATOM   5819 C  CD  . GLN   C 1 186 ? 24.429  -32.353 22.159  1.00 43.71  ? 172 GLN   L CD  1 
ATOM   5820 O  OE1 . GLN   C 1 186 ? 24.142  -31.176 21.977  1.00 49.28  ? 172 GLN   L OE1 1 
ATOM   5821 N  NE2 . GLN   C 1 186 ? 23.941  -33.029 23.178  1.00 44.58  ? 172 GLN   L NE2 1 
ATOM   5822 N  N   . TRP   C 1 187 ? 21.329  -33.228 18.340  1.00 36.25  ? 173 TRP   L N   1 
ATOM   5823 C  CA  . TRP   C 1 187 ? 20.483  -33.270 17.118  1.00 37.82  ? 173 TRP   L CA  1 
ATOM   5824 C  C   . TRP   C 1 187 ? 20.557  -31.944 16.363  1.00 37.94  ? 173 TRP   L C   1 
ATOM   5825 O  O   . TRP   C 1 187 ? 20.478  -30.891 16.987  1.00 38.07  ? 173 TRP   L O   1 
ATOM   5826 C  CB  . TRP   C 1 187 ? 19.046  -33.618 17.500  1.00 34.56  ? 173 TRP   L CB  1 
ATOM   5827 C  CG  . TRP   C 1 187 ? 18.903  -34.895 18.268  1.00 35.07  ? 173 TRP   L CG  1 
ATOM   5828 C  CD1 . TRP   C 1 187 ? 18.894  -35.082 19.619  1.00 39.18  ? 173 TRP   L CD1 1 
ATOM   5829 C  CD2 . TRP   C 1 187 ? 18.671  -36.182 17.693  1.00 34.98  ? 173 TRP   L CD2 1 
ATOM   5830 N  NE1 . TRP   C 1 187 ? 18.652  -36.399 19.914  1.00 37.25  ? 173 TRP   L NE1 1 
ATOM   5831 C  CE2 . TRP   C 1 187 ? 18.491  -37.096 18.755  1.00 38.68  ? 173 TRP   L CE2 1 
ATOM   5832 C  CE3 . TRP   C 1 187 ? 18.533  -36.633 16.377  1.00 38.66  ? 173 TRP   L CE3 1 
ATOM   5833 C  CZ2 . TRP   C 1 187 ? 18.254  -38.452 18.545  1.00 37.05  ? 173 TRP   L CZ2 1 
ATOM   5834 C  CZ3 . TRP   C 1 187 ? 18.288  -37.974 16.171  1.00 40.23  ? 173 TRP   L CZ3 1 
ATOM   5835 C  CH2 . TRP   C 1 187 ? 18.144  -38.860 17.244  1.00 38.50  ? 173 TRP   L CH2 1 
ATOM   5836 N  N   . ARG   C 1 188 ? 20.668  -32.034 15.053  1.00 38.53  ? 174 ARG   L N   1 
ATOM   5837 C  CA  . ARG   C 1 188 ? 20.320  -30.957 14.110  1.00 37.52  ? 174 ARG   L CA  1 
ATOM   5838 C  C   . ARG   C 1 188 ? 19.166  -31.471 13.236  1.00 35.42  ? 174 ARG   L C   1 
ATOM   5839 O  O   . ARG   C 1 188 ? 19.389  -32.396 12.417  1.00 35.60  ? 174 ARG   L O   1 
ATOM   5840 C  CB  . ARG   C 1 188 ? 21.490  -30.529 13.230  1.00 41.85  ? 174 ARG   L CB  1 
ATOM   5841 C  CG  . ARG   C 1 188 ? 21.159  -29.276 12.417  1.00 46.79  ? 174 ARG   L CG  1 
ATOM   5842 C  CD  . ARG   C 1 188 ? 21.475  -29.461 10.954  1.00 60.02  ? 174 ARG   L CD  1 
ATOM   5843 N  NE  . ARG   C 1 188 ? 21.493  -28.245 10.161  1.00 55.47  ? 174 ARG   L NE  1 
ATOM   5844 C  CZ  . ARG   C 1 188 ? 20.445  -27.644 9.602   1.00 57.88  ? 174 ARG   L CZ  1 
ATOM   5845 N  NH1 . ARG   C 1 188 ? 19.200  -28.074 9.770   1.00 52.76  ? 174 ARG   L NH1 1 
ATOM   5846 N  NH2 . ARG   C 1 188 ? 20.655  -26.566 8.872   1.00 51.81  ? 174 ARG   L NH2 1 
ATOM   5847 N  N   . THR   C 1 189 ? 17.974  -30.891 13.393  1.00 32.01  ? 175 THR   L N   1 
ATOM   5848 C  CA  . THR   C 1 189 ? 16.794  -31.298 12.593  1.00 32.22  ? 175 THR   L CA  1 
ATOM   5849 C  C   . THR   C 1 189 ? 16.802  -30.511 11.283  1.00 32.16  ? 175 THR   L C   1 
ATOM   5850 O  O   . THR   C 1 189 ? 17.161  -29.299 11.263  1.00 33.59  ? 175 THR   L O   1 
ATOM   5851 C  CB  . THR   C 1 189 ? 15.467  -31.144 13.337  1.00 35.29  ? 175 THR   L CB  1 
ATOM   5852 O  OG1 . THR   C 1 189 ? 15.356  -29.784 13.740  1.00 36.55  ? 175 THR   L OG1 1 
ATOM   5853 C  CG2 . THR   C 1 189 ? 15.332  -32.080 14.514  1.00 36.91  ? 175 THR   L CG2 1 
ATOM   5854 N  N   . VAL   C 1 190 ? 16.543  -31.214 10.197  1.00 30.07  ? 176 VAL   L N   1 
ATOM   5855 C  CA  . VAL   C 1 190 ? 16.309  -30.608 8.859   1.00 31.58  ? 176 VAL   L CA  1 
ATOM   5856 C  C   . VAL   C 1 190 ? 14.844  -30.193 8.817   1.00 31.74  ? 176 VAL   L C   1 
ATOM   5857 O  O   . VAL   C 1 190 ? 13.939  -31.045 9.015   1.00 32.35  ? 176 VAL   L O   1 
ATOM   5858 C  CB  . VAL   C 1 190 ? 16.721  -31.573 7.728   1.00 33.62  ? 176 VAL   L CB  1 
ATOM   5859 C  CG1 . VAL   C 1 190 ? 16.540  -30.944 6.357   1.00 33.90  ? 176 VAL   L CG1 1 
ATOM   5860 C  CG2 . VAL   C 1 190 ? 18.175  -32.001 7.919   1.00 34.61  ? 176 VAL   L CG2 1 
ATOM   5861 N  N   . LYS   C 1 191 ? 14.610  -28.903 8.595   1.00 33.41  ? 177 LYS   L N   1 
ATOM   5862 C  CA  . LYS   C 1 191 ? 13.229  -28.344 8.614   1.00 33.58  ? 177 LYS   L CA  1 
ATOM   5863 C  C   . LYS   C 1 191 ? 12.502  -28.782 7.341   1.00 34.49  ? 177 LYS   L C   1 
ATOM   5864 O  O   . LYS   C 1 191 ? 13.136  -29.124 6.283   1.00 32.88  ? 177 LYS   L O   1 
ATOM   5865 C  CB  . LYS   C 1 191 ? 13.226  -26.816 8.780   1.00 37.68  ? 177 LYS   L CB  1 
ATOM   5866 C  CG  . LYS   C 1 191 ? 14.040  -26.261 9.966   1.00 48.07  ? 177 LYS   L CG  1 
ATOM   5867 C  CD  . LYS   C 1 191 ? 13.681  -26.814 11.351  1.00 57.14  ? 177 LYS   L CD  1 
ATOM   5868 C  CE  . LYS   C 1 191 ? 14.525  -26.258 12.509  1.00 54.32  ? 177 LYS   L CE  1 
ATOM   5869 N  NZ  . LYS   C 1 191 ? 15.810  -26.983 12.730  1.00 49.27  ? 177 LYS   L NZ  1 
ATOM   5870 N  N   . ARG   C 1 192 ? 11.195  -28.888 7.455   1.00 35.66  ? 178 ARG   L N   1 
ATOM   5871 C  CA  . ARG   C 1 192 ? 10.327  -29.326 6.348   1.00 39.88  ? 178 ARG   L CA  1 
ATOM   5872 C  C   . ARG   C 1 192 ? 10.692  -28.601 5.047   1.00 44.03  ? 178 ARG   L C   1 
ATOM   5873 O  O   . ARG   C 1 192 ? 10.775  -29.264 4.031   1.00 44.52  ? 178 ARG   L O   1 
ATOM   5874 C  CB  . ARG   C 1 192 ? 8.855   -29.140 6.734   1.00 36.63  ? 178 ARG   L CB  1 
ATOM   5875 C  CG  . ARG   C 1 192 ? 7.925   -29.898 5.810   1.00 38.82  ? 178 ARG   L CG  1 
ATOM   5876 C  CD  . ARG   C 1 192 ? 6.474   -29.724 6.221   1.00 37.47  ? 178 ARG   L CD  1 
ATOM   5877 N  NE  . ARG   C 1 192 ? 6.183   -30.573 7.357   1.00 34.13  ? 178 ARG   L NE  1 
ATOM   5878 C  CZ  . ARG   C 1 192 ? 5.041   -30.544 8.003   1.00 37.76  ? 178 ARG   L CZ  1 
ATOM   5879 N  NH1 . ARG   C 1 192 ? 4.087   -29.701 7.618   1.00 32.68  ? 178 ARG   L NH1 1 
ATOM   5880 N  NH2 . ARG   C 1 192 ? 4.867   -31.326 9.061   1.00 34.22  ? 178 ARG   L NH2 1 
ATOM   5881 N  N   . HIS   C 1 193 ? 10.923  -27.293 5.021   1.00 43.89  ? 179 HIS   L N   1 
ATOM   5882 C  CA  . HIS   C 1 193 ? 11.179  -26.651 3.700   1.00 53.78  ? 179 HIS   L CA  1 
ATOM   5883 C  C   . HIS   C 1 193 ? 12.657  -26.284 3.560   1.00 54.27  ? 179 HIS   L C   1 
ATOM   5884 O  O   . HIS   C 1 193 ? 12.979  -25.418 2.762   1.00 55.91  ? 179 HIS   L O   1 
ATOM   5885 C  CB  . HIS   C 1 193 ? 10.213  -25.464 3.470   1.00 58.33  ? 179 HIS   L CB  1 
ATOM   5886 C  CG  . HIS   C 1 193 ? 8.783   -25.899 3.529   1.00 65.80  ? 179 HIS   L CG  1 
ATOM   5887 N  ND1 . HIS   C 1 193 ? 8.277   -26.901 2.680   1.00 62.75  ? 179 HIS   L ND1 1 
ATOM   5888 C  CD2 . HIS   C 1 193 ? 7.778   -25.561 4.377   1.00 66.49  ? 179 HIS   L CD2 1 
ATOM   5889 C  CE1 . HIS   C 1 193 ? 7.009   -27.135 2.984   1.00 61.99  ? 179 HIS   L CE1 1 
ATOM   5890 N  NE2 . HIS   C 1 193 ? 6.676   -26.318 4.024   1.00 73.18  ? 179 HIS   L NE2 1 
ATOM   5891 N  N   . GLU   C 1 194 ? 13.541  -26.950 4.279   1.00 42.37  ? 180 GLU   L N   1 
ATOM   5892 C  CA  . GLU   C 1 194 ? 14.964  -26.567 4.258   1.00 42.26  ? 180 GLU   L CA  1 
ATOM   5893 C  C   . GLU   C 1 194 ? 15.640  -27.207 3.054   1.00 51.11  ? 180 GLU   L C   1 
ATOM   5894 O  O   . GLU   C 1 194 ? 15.432  -28.403 2.827   1.00 45.46  ? 180 GLU   L O   1 
ATOM   5895 C  CB  . GLU   C 1 194 ? 15.677  -27.036 5.511   1.00 42.98  ? 180 GLU   L CB  1 
ATOM   5896 C  CG  . GLU   C 1 194 ? 16.877  -26.197 5.840   1.00 44.57  ? 180 GLU   L CG  1 
ATOM   5897 C  CD  . GLU   C 1 194 ? 17.538  -26.561 7.161   1.00 46.59  ? 180 GLU   L CD  1 
ATOM   5898 O  OE1 . GLU   C 1 194 ? 16.884  -27.173 8.061   1.00 39.06  ? 180 GLU   L OE1 1 
ATOM   5899 O  OE2 . GLU   C 1 194 ? 18.703  -26.264 7.261   1.00 48.19  ? 180 GLU   L OE2 1 
ATOM   5900 N  N   . ASP   C 1 195 ? 16.493  -26.396 2.436   1.00 57.41  ? 181 ASP   L N   1 
ATOM   5901 C  CA  . ASP   C 1 195 ? 17.337  -26.651 1.246   1.00 76.91  ? 181 ASP   L CA  1 
ATOM   5902 C  C   . ASP   C 1 195 ? 18.330  -27.768 1.560   1.00 53.30  ? 181 ASP   L C   1 
ATOM   5903 O  O   . ASP   C 1 195 ? 18.437  -28.129 2.716   1.00 87.42  ? 181 ASP   L O   1 
ATOM   5904 C  CB  . ASP   C 1 195 ? 18.073  -25.350 0.880   1.00 82.21  ? 181 ASP   L CB  1 
ATOM   5905 C  CG  . ASP   C 1 195 ? 17.204  -24.226 0.319   1.00 86.40  ? 181 ASP   L CG  1 
ATOM   5906 O  OD1 . ASP   C 1 195 ? 15.964  -24.397 0.215   1.00 78.11  ? 181 ASP   L OD1 1 
ATOM   5907 O  OD2 . ASP   C 1 195 ? 17.781  -23.178 -0.016  1.00 79.52  ? 181 ASP   L OD2 1 
ATOM   5908 N  N   . ASN   C 1 196 ? 19.020  -28.265 0.568   1.00 47.61  ? 182 ASN   L N   1 
ATOM   5909 C  CA  . ASN   C 1 196 ? 20.055  -29.310 0.682   1.00 45.87  ? 182 ASN   L CA  1 
ATOM   5910 C  C   . ASN   C 1 196 ? 21.351  -28.730 1.295   1.00 50.22  ? 182 ASN   L C   1 
ATOM   5911 O  O   . ASN   C 1 196 ? 22.027  -27.863 0.724   1.00 49.30  ? 182 ASN   L O   1 
ATOM   5912 C  CB  . ASN   C 1 196 ? 20.385  -29.948 -0.647  1.00 61.93  ? 182 ASN   L CB  1 
ATOM   5913 C  CG  . ASN   C 1 196 ? 19.144  -30.171 -1.472  1.00 72.99  ? 182 ASN   L CG  1 
ATOM   5914 O  OD1 . ASN   C 1 196 ? 19.191  -29.815 -2.663  1.00 67.05  ? 182 ASN   L OD1 1 
ATOM   5915 N  ND2 . ASN   C 1 196 ? 18.058  -30.673 -0.822  1.00 54.08  ? 182 ASN   L ND2 1 
ATOM   5916 N  N   . ILE   C 1 197 ? 21.738  -29.306 2.406   1.00 35.68  ? 183 ILE   L N   1 
ATOM   5917 C  CA  . ILE   C 1 197 ? 22.749  -28.789 3.348   1.00 39.69  ? 183 ILE   L CA  1 
ATOM   5918 C  C   . ILE   C 1 197 ? 24.129  -29.268 2.919   1.00 38.14  ? 183 ILE   L C   1 
ATOM   5919 O  O   . ILE   C 1 197 ? 24.320  -30.483 2.733   1.00 37.14  ? 183 ILE   L O   1 
ATOM   5920 C  CB  . ILE   C 1 197 ? 22.401  -29.254 4.762   1.00 43.23  ? 183 ILE   L CB  1 
ATOM   5921 C  CG1 . ILE   C 1 197 ? 20.991  -28.787 5.136   1.00 46.89  ? 183 ILE   L CG1 1 
ATOM   5922 C  CG2 . ILE   C 1 197 ? 23.463  -28.804 5.761   1.00 49.72  ? 183 ILE   L CG2 1 
ATOM   5923 C  CD1 . ILE   C 1 197 ? 20.270  -29.755 6.036   1.00 54.97  ? 183 ILE   L CD1 1 
ATOM   5924 N  N   . LEU   C 1 198 ? 25.026  -28.302 2.754   1.00 39.52  ? 184 LEU   L N   1 
ATOM   5925 C  CA  . LEU   C 1 198 ? 26.448  -28.556 2.461   1.00 45.63  ? 184 LEU   L CA  1 
ATOM   5926 C  C   . LEU   C 1 198 ? 27.099  -28.989 3.773   1.00 44.90  ? 184 LEU   L C   1 
ATOM   5927 O  O   . LEU   C 1 198 ? 27.165  -28.198 4.693   1.00 46.75  ? 184 LEU   L O   1 
ATOM   5928 C  CB  . LEU   C 1 198 ? 27.095  -27.293 1.899   1.00 52.98  ? 184 LEU   L CB  1 
ATOM   5929 C  CG  . LEU   C 1 198 ? 28.612  -27.415 1.709   1.00 61.29  ? 184 LEU   L CG  1 
ATOM   5930 C  CD1 . LEU   C 1 198 ? 28.925  -28.407 0.593   1.00 62.59  ? 184 LEU   L CD1 1 
ATOM   5931 C  CD2 . LEU   C 1 198 ? 29.252  -26.062 1.422   1.00 61.77  ? 184 LEU   L CD2 1 
ATOM   5932 N  N   . LEU   C 1 199 ? 27.512  -30.242 3.871   1.00 43.88  ? 185 LEU   L N   1 
ATOM   5933 C  CA  . LEU   C 1 199 ? 28.171  -30.773 5.081   1.00 40.71  ? 185 LEU   L CA  1 
ATOM   5934 C  C   . LEU   C 1 199 ? 29.680  -30.587 4.975   1.00 41.57  ? 185 LEU   L C   1 
ATOM   5935 O  O   . LEU   C 1 199 ? 30.327  -30.378 5.990   1.00 46.03  ? 185 LEU   L O   1 
ATOM   5936 C  CB  . LEU   C 1 199 ? 27.836  -32.256 5.177   1.00 43.03  ? 185 LEU   L CB  1 
ATOM   5937 C  CG  . LEU   C 1 199 ? 26.693  -32.654 6.084   1.00 45.85  ? 185 LEU   L CG  1 
ATOM   5938 C  CD1 . LEU   C 1 199 ? 26.792  -34.151 6.377   1.00 44.50  ? 185 LEU   L CD1 1 
ATOM   5939 C  CD2 . LEU   C 1 199 ? 26.685  -31.830 7.371   1.00 51.98  ? 185 LEU   L CD2 1 
ATOM   5940 N  N   . ALA   C 1 200 ? 30.218  -30.752 3.770   1.00 40.84  ? 186 ALA   L N   1 
ATOM   5941 C  CA  . ALA   C 1 200 ? 31.656  -30.732 3.476   1.00 42.16  ? 186 ALA   L CA  1 
ATOM   5942 C  C   . ALA   C 1 200 ? 31.838  -30.649 1.966   1.00 41.63  ? 186 ALA   L C   1 
ATOM   5943 O  O   . ALA   C 1 200 ? 30.859  -30.828 1.246   1.00 39.02  ? 186 ALA   L O   1 
ATOM   5944 C  CB  . ALA   C 1 200 ? 32.307  -31.961 4.073   1.00 46.25  ? 186 ALA   L CB  1 
ATOM   5945 N  N   . GLU   C 1 201 ? 33.043  -30.323 1.493   1.00 39.94  ? 187 GLU   L N   1 
ATOM   5946 C  CA  . GLU   C 1 201 ? 33.290  -30.240 0.034   1.00 42.78  ? 187 GLU   L CA  1 
ATOM   5947 C  C   . GLU   C 1 201 ? 32.806  -31.540 -0.633  1.00 41.15  ? 187 GLU   L C   1 
ATOM   5948 O  O   . GLU   C 1 201 ? 33.227  -32.619 -0.206  1.00 39.17  ? 187 GLU   L O   1 
ATOM   5949 C  CB  . GLU   C 1 201 ? 34.784  -30.017 -0.231  1.00 47.82  ? 187 GLU   L CB  1 
ATOM   5950 C  CG  . GLU   C 1 201 ? 35.048  -29.608 -1.664  1.00 54.21  ? 187 GLU   L CG  1 
ATOM   5951 C  CD  . GLU   C 1 201 ? 36.530  -29.511 -1.963  1.00 57.62  ? 187 GLU   L CD  1 
ATOM   5952 O  OE1 . GLU   C 1 201 ? 37.312  -29.721 -1.035  1.00 53.50  ? 187 GLU   L OE1 1 
ATOM   5953 O  OE2 . GLU   C 1 201 ? 36.879  -29.238 -3.110  1.00 60.62  ? 187 GLU   L OE2 1 
ATOM   5954 N  N   . GLY   C 1 202 ? 31.898  -31.422 -1.597  1.00 37.22  ? 188 GLY   L N   1 
ATOM   5955 C  CA  . GLY   C 1 202 ? 31.311  -32.547 -2.349  1.00 38.55  ? 188 GLY   L CA  1 
ATOM   5956 C  C   . GLY   C 1 202 ? 30.358  -33.422 -1.560  1.00 39.04  ? 188 GLY   L C   1 
ATOM   5957 O  O   . GLY   C 1 202 ? 30.112  -34.506 -2.038  1.00 40.05  ? 188 GLY   L O   1 
ATOM   5958 N  N   . VAL   C 1 203 ? 29.830  -32.991 -0.403  1.00 36.06  ? 189 VAL   L N   1 
ATOM   5959 C  CA  . VAL   C 1 203 ? 28.874  -33.820 0.376   1.00 35.21  ? 189 VAL   L CA  1 
ATOM   5960 C  C   . VAL   C 1 203 ? 27.684  -32.947 0.773   1.00 37.00  ? 189 VAL   L C   1 
ATOM   5961 O  O   . VAL   C 1 203 ? 27.877  -31.965 1.536   1.00 37.38  ? 189 VAL   L O   1 
ATOM   5962 C  CB  . VAL   C 1 203 ? 29.500  -34.454 1.625   1.00 37.97  ? 189 VAL   L CB  1 
ATOM   5963 C  CG1 . VAL   C 1 203 ? 28.451  -35.297 2.328   1.00 39.37  ? 189 VAL   L CG1 1 
ATOM   5964 C  CG2 . VAL   C 1 203 ? 30.737  -35.300 1.259   1.00 36.37  ? 189 VAL   L CG2 1 
ATOM   5965 N  N   . LYS   C 1 204 ? 26.509  -33.335 0.293   1.00 36.31  ? 190 LYS   L N   1 
ATOM   5966 C  CA  . LYS   C 1 204 ? 25.275  -32.528 0.384   1.00 38.57  ? 190 LYS   L CA  1 
ATOM   5967 C  C   . LYS   C 1 204 ? 24.201  -33.453 0.965   1.00 32.57  ? 190 LYS   L C   1 
ATOM   5968 O  O   . LYS   C 1 204 ? 24.025  -34.556 0.406   1.00 34.48  ? 190 LYS   L O   1 
ATOM   5969 C  CB  . LYS   C 1 204 ? 24.962  -32.028 -1.035  1.00 42.03  ? 190 LYS   L CB  1 
ATOM   5970 C  CG  . LYS   C 1 204 ? 23.867  -30.985 -1.150  1.00 54.76  ? 190 LYS   L CG  1 
ATOM   5971 C  CD  . LYS   C 1 204 ? 23.288  -30.819 -2.556  1.00 58.60  ? 190 LYS   L CD  1 
ATOM   5972 C  CE  . LYS   C 1 204 ? 24.313  -30.309 -3.532  1.00 71.87  ? 190 LYS   L CE  1 
ATOM   5973 N  NZ  . LYS   C 1 204 ? 23.649  -29.896 -4.784  1.00 75.93  ? 190 LYS   L NZ  1 
ATOM   5974 N  N   . VAL   C 1 205 ? 23.506  -32.986 1.999   1.00 32.65  ? 191 VAL   L N   1 
ATOM   5975 C  CA  . VAL   C 1 205 ? 22.292  -33.656 2.517   1.00 32.72  ? 191 VAL   L CA  1 
ATOM   5976 C  C   . VAL   C 1 205 ? 21.115  -33.252 1.631   1.00 33.56  ? 191 VAL   L C   1 
ATOM   5977 O  O   . VAL   C 1 205 ? 20.796  -32.029 1.564   1.00 36.54  ? 191 VAL   L O   1 
ATOM   5978 C  CB  . VAL   C 1 205 ? 22.024  -33.322 4.000   1.00 36.94  ? 191 VAL   L CB  1 
ATOM   5979 C  CG1 . VAL   C 1 205 ? 20.775  -34.067 4.471   1.00 39.73  ? 191 VAL   L CG1 1 
ATOM   5980 C  CG2 . VAL   C 1 205 ? 23.214  -33.633 4.900   1.00 36.55  ? 191 VAL   L CG2 1 
ATOM   5981 N  N   . LEU   C 1 206 ? 20.409  -34.233 1.091   1.00 33.10  ? 192 LEU   L N   1 
ATOM   5982 C  CA  . LEU   C 1 206 ? 19.168  -34.014 0.306   1.00 33.31  ? 192 LEU   L CA  1 
ATOM   5983 C  C   . LEU   C 1 206 ? 17.948  -34.197 1.209   1.00 31.55  ? 192 LEU   L C   1 
ATOM   5984 O  O   . LEU   C 1 206 ? 17.799  -35.239 1.846   1.00 34.90  ? 192 LEU   L O   1 
ATOM   5985 C  CB  . LEU   C 1 206 ? 19.126  -34.992 -0.850  1.00 33.14  ? 192 LEU   L CB  1 
ATOM   5986 C  CG  . LEU   C 1 206 ? 20.365  -34.970 -1.747  1.00 39.29  ? 192 LEU   L CG  1 
ATOM   5987 C  CD1 . LEU   C 1 206 ? 20.375  -36.174 -2.684  1.00 38.26  ? 192 LEU   L CD1 1 
ATOM   5988 C  CD2 . LEU   C 1 206 ? 20.427  -33.681 -2.553  1.00 40.42  ? 192 LEU   L CD2 1 
ATOM   5989 N  N   . ASN   C 1 207 ? 17.083  -33.217 1.224   1.00 32.65  ? 193 ASN   L N   1 
ATOM   5990 C  CA  . ASN   C 1 207 ? 15.815  -33.289 1.965   1.00 33.99  ? 193 ASN   L CA  1 
ATOM   5991 C  C   . ASN   C 1 207 ? 14.747  -33.843 1.035   1.00 33.68  ? 193 ASN   L C   1 
ATOM   5992 O  O   . ASN   C 1 207 ? 14.156  -33.092 0.230   1.00 31.75  ? 193 ASN   L O   1 
ATOM   5993 C  CB  . ASN   C 1 207 ? 15.449  -31.945 2.562   1.00 35.16  ? 193 ASN   L CB  1 
ATOM   5994 C  CG  . ASN   C 1 207 ? 14.208  -32.044 3.440   1.00 31.05  ? 193 ASN   L CG  1 
ATOM   5995 O  OD1 . ASN   C 1 207 ? 13.541  -33.073 3.504   1.00 33.64  ? 193 ASN   L OD1 1 
ATOM   5996 N  ND2 . ASN   C 1 207 ? 13.785  -30.924 3.968   1.00 37.73  ? 193 ASN   L ND2 1 
ATOM   5997 N  N   . PHE   C 1 208 ? 14.503  -35.140 1.125   1.00 32.91  ? 194 PHE   L N   1 
ATOM   5998 C  CA  . PHE   C 1 208 ? 13.486  -35.819 0.282   1.00 33.71  ? 194 PHE   L CA  1 
ATOM   5999 C  C   . PHE   C 1 208 ? 12.060  -35.591 0.810   1.00 34.28  ? 194 PHE   L C   1 
ATOM   6000 O  O   . PHE   C 1 208 ? 11.130  -35.750 0.062   1.00 35.17  ? 194 PHE   L O   1 
ATOM   6001 C  CB  . PHE   C 1 208 ? 13.768  -37.312 0.166   1.00 34.91  ? 194 PHE   L CB  1 
ATOM   6002 C  CG  . PHE   C 1 208 ? 15.034  -37.682 -0.566  1.00 34.51  ? 194 PHE   L CG  1 
ATOM   6003 C  CD1 . PHE   C 1 208 ? 15.472  -36.970 -1.689  1.00 33.56  ? 194 PHE   L CD1 1 
ATOM   6004 C  CD2 . PHE   C 1 208 ? 15.726  -38.827 -0.201  1.00 36.14  ? 194 PHE   L CD2 1 
ATOM   6005 C  CE1 . PHE   C 1 208 ? 16.609  -37.360 -2.377  1.00 31.83  ? 194 PHE   L CE1 1 
ATOM   6006 C  CE2 . PHE   C 1 208 ? 16.853  -39.216 -0.904  1.00 35.84  ? 194 PHE   L CE2 1 
ATOM   6007 C  CZ  . PHE   C 1 208 ? 17.289  -38.488 -1.984  1.00 33.94  ? 194 PHE   L CZ  1 
ATOM   6008 N  N   . GLY   C 1 209 ? 11.906  -35.317 2.097   1.00 37.25  ? 195 GLY   L N   1 
ATOM   6009 C  CA  . GLY   C 1 209 ? 10.613  -35.110 2.755   1.00 39.43  ? 195 GLY   L CA  1 
ATOM   6010 C  C   . GLY   C 1 209 ? 9.863   -36.411 2.940   1.00 36.20  ? 195 GLY   L C   1 
ATOM   6011 O  O   . GLY   C 1 209 ? 10.484  -37.514 2.910   1.00 34.92  ? 195 GLY   L O   1 
ATOM   6012 N  N   . SER   C 1 210 ? 8.546   -36.307 3.098   1.00 33.97  ? 196 SER   L N   1 
ATOM   6013 C  CA  . SER   C 1 210 ? 7.696   -37.456 3.486   1.00 33.64  ? 196 SER   L CA  1 
ATOM   6014 C  C   . SER   C 1 210 ? 7.559   -38.393 2.282   1.00 31.34  ? 196 SER   L C   1 
ATOM   6015 O  O   . SER   C 1 210 ? 7.553   -37.941 1.117   1.00 33.11  ? 196 SER   L O   1 
ATOM   6016 C  CB  . SER   C 1 210 ? 6.341   -36.988 4.017   1.00 34.10  ? 196 SER   L CB  1 
ATOM   6017 O  OG  . SER   C 1 210 ? 5.771   -36.064 3.103   1.00 34.17  ? 196 SER   L OG  1 
ATOM   6018 N  N   . GLY   C 1 211 ? 7.486   -39.685 2.539   1.00 30.91  ? 197 GLY   L N   1 
ATOM   6019 C  CA  . GLY   C 1 211 ? 7.315   -40.676 1.478   1.00 32.06  ? 197 GLY   L CA  1 
ATOM   6020 C  C   . GLY   C 1 211 ? 7.213   -42.039 2.103   1.00 31.84  ? 197 GLY   L C   1 
ATOM   6021 O  O   . GLY   C 1 211 ? 6.202   -42.324 2.764   1.00 32.04  ? 197 GLY   L O   1 
ATOM   6022 N  N   . HIS   C 1 212 ? 8.296   -42.809 2.031   1.00 31.82  ? 198 HIS   L N   1 
ATOM   6023 C  CA  . HIS   C 1 212 ? 8.432   -44.077 2.783   1.00 30.95  ? 198 HIS   L CA  1 
ATOM   6024 C  C   . HIS   C 1 212 ? 8.146   -43.871 4.276   1.00 32.40  ? 198 HIS   L C   1 
ATOM   6025 O  O   . HIS   C 1 212 ? 7.450   -44.674 4.808   1.00 33.39  ? 198 HIS   L O   1 
ATOM   6026 C  CB  . HIS   C 1 212 ? 9.832   -44.626 2.599   1.00 33.55  ? 198 HIS   L CB  1 
ATOM   6027 C  CG  . HIS   C 1 212 ? 10.217  -45.724 3.516   1.00 33.94  ? 198 HIS   L CG  1 
ATOM   6028 N  ND1 . HIS   C 1 212 ? 9.772   -47.016 3.300   1.00 35.14  ? 198 HIS   L ND1 1 
ATOM   6029 C  CD2 . HIS   C 1 212 ? 11.085  -45.770 4.558   1.00 35.90  ? 198 HIS   L CD2 1 
ATOM   6030 C  CE1 . HIS   C 1 212 ? 10.347  -47.818 4.185   1.00 34.70  ? 198 HIS   L CE1 1 
ATOM   6031 N  NE2 . HIS   C 1 212 ? 11.157  -47.076 4.977   1.00 36.35  ? 198 HIS   L NE2 1 
ATOM   6032 N  N   . ALA   C 1 213 ? 8.727   -42.847 4.903   1.00 33.20  ? 199 ALA   L N   1 
ATOM   6033 C  CA  . ALA   C 1 213 ? 8.505   -42.514 6.321   1.00 34.70  ? 199 ALA   L CA  1 
ATOM   6034 C  C   . ALA   C 1 213 ? 8.104   -41.040 6.421   1.00 30.74  ? 199 ALA   L C   1 
ATOM   6035 O  O   . ALA   C 1 213 ? 7.818   -40.402 5.368   1.00 32.93  ? 199 ALA   L O   1 
ATOM   6036 C  CB  . ALA   C 1 213 ? 9.717   -42.897 7.157   1.00 32.45  ? 199 ALA   L CB  1 
ATOM   6037 N  N   . TRP   C 1 214 ? 8.003   -40.532 7.640   1.00 31.23  ? 200 TRP   L N   1 
ATOM   6038 C  CA  . TRP   C 1 214 ? 7.625   -39.118 7.897   1.00 34.30  ? 200 TRP   L CA  1 
ATOM   6039 C  C   . TRP   C 1 214 ? 8.599   -38.162 7.221   1.00 35.79  ? 200 TRP   L C   1 
ATOM   6040 O  O   . TRP   C 1 214 ? 8.147   -37.126 6.758   1.00 31.92  ? 200 TRP   L O   1 
ATOM   6041 C  CB  . TRP   C 1 214 ? 7.515   -38.817 9.386   1.00 32.09  ? 200 TRP   L CB  1 
ATOM   6042 C  CG  . TRP   C 1 214 ? 6.469   -39.631 10.067  1.00 37.32  ? 200 TRP   L CG  1 
ATOM   6043 C  CD1 . TRP   C 1 214 ? 5.135   -39.605 9.788   1.00 41.83  ? 200 TRP   L CD1 1 
ATOM   6044 C  CD2 . TRP   C 1 214 ? 6.628   -40.518 11.189  1.00 34.38  ? 200 TRP   L CD2 1 
ATOM   6045 N  NE1 . TRP   C 1 214 ? 4.464   -40.474 10.603  1.00 41.57  ? 200 TRP   L NE1 1 
ATOM   6046 C  CE2 . TRP   C 1 214 ? 5.342   -41.039 11.478  1.00 40.27  ? 200 TRP   L CE2 1 
ATOM   6047 C  CE3 . TRP   C 1 214 ? 7.719   -40.980 11.940  1.00 35.09  ? 200 TRP   L CE3 1 
ATOM   6048 C  CZ2 . TRP   C 1 214 ? 5.115   -41.962 12.500  1.00 39.95  ? 200 TRP   L CZ2 1 
ATOM   6049 C  CZ3 . TRP   C 1 214 ? 7.493   -41.883 12.954  1.00 37.12  ? 200 TRP   L CZ3 1 
ATOM   6050 C  CH2 . TRP   C 1 214 ? 6.209   -42.362 13.234  1.00 39.63  ? 200 TRP   L CH2 1 
ATOM   6051 N  N   . GLY   C 1 215 ? 9.902   -38.437 7.236   1.00 28.70  ? 201 GLY   L N   1 
ATOM   6052 C  CA  . GLY   C 1 215 ? 10.873  -37.504 6.658   1.00 30.68  ? 201 GLY   L CA  1 
ATOM   6053 C  C   . GLY   C 1 215 ? 12.151  -38.224 6.270   1.00 31.36  ? 201 GLY   L C   1 
ATOM   6054 O  O   . GLY   C 1 215 ? 12.860  -38.678 7.147   1.00 34.91  ? 201 GLY   L O   1 
ATOM   6055 N  N   . MET   C 1 216 ? 12.474  -38.220 4.989   1.00 31.85  ? 202 MET   L N   1 
ATOM   6056 C  CA  . MET   C 1 216 ? 13.581  -39.017 4.440   1.00 31.80  ? 202 MET   L CA  1 
ATOM   6057 C  C   . MET   C 1 216 ? 14.738  -38.051 4.118   1.00 33.31  ? 202 MET   L C   1 
ATOM   6058 O  O   . MET   C 1 216 ? 14.487  -37.000 3.493   1.00 31.98  ? 202 MET   L O   1 
ATOM   6059 C  CB  . MET   C 1 216 ? 13.133  -39.746 3.169   1.00 31.26  ? 202 MET   L CB  1 
ATOM   6060 C  CG  . MET   C 1 216 ? 11.944  -40.653 3.385   1.00 36.44  ? 202 MET   L CG  1 
ATOM   6061 S  SD  . MET   C 1 216 ? 12.265  -41.973 4.570   1.00 36.19  ? 202 MET   L SD  1 
ATOM   6062 C  CE  . MET   C 1 216 ? 13.457  -43.023 3.745   1.00 36.44  ? 202 MET   L CE  1 
ATOM   6063 N  N   . LEU   C 1 217 ? 15.972  -38.427 4.465   1.00 29.41  ? 203 LEU   L N   1 
ATOM   6064 C  CA  . LEU   C 1 217 ? 17.166  -37.690 3.967   1.00 30.05  ? 203 LEU   L CA  1 
ATOM   6065 C  C   . LEU   C 1 217 ? 18.006  -38.621 3.099   1.00 34.15  ? 203 LEU   L C   1 
ATOM   6066 O  O   . LEU   C 1 217 ? 18.089  -39.863 3.396   1.00 32.25  ? 203 LEU   L O   1 
ATOM   6067 C  CB  . LEU   C 1 217 ? 17.993  -37.132 5.121   1.00 31.22  ? 203 LEU   L CB  1 
ATOM   6068 C  CG  . LEU   C 1 217 ? 17.296  -36.256 6.166   1.00 33.77  ? 203 LEU   L CG  1 
ATOM   6069 C  CD1 . LEU   C 1 217 ? 18.295  -35.854 7.267   1.00 35.13  ? 203 LEU   L CD1 1 
ATOM   6070 C  CD2 . LEU   C 1 217 ? 16.719  -35.003 5.523   1.00 32.35  ? 203 LEU   L CD2 1 
ATOM   6071 N  N   . GLY   C 1 218 ? 18.561  -38.037 2.049   1.00 32.67  ? 204 GLY   L N   1 
ATOM   6072 C  CA  . GLY   C 1 218 ? 19.554  -38.692 1.217   1.00 29.44  ? 204 GLY   L CA  1 
ATOM   6073 C  C   . GLY   C 1 218 ? 20.864  -37.951 1.306   1.00 30.95  ? 204 GLY   L C   1 
ATOM   6074 O  O   . GLY   C 1 218 ? 20.929  -36.920 1.962   1.00 31.75  ? 204 GLY   L O   1 
ATOM   6075 N  N   . LEU   C 1 219 ? 21.867  -38.457 0.592   1.00 30.64  ? 205 LEU   L N   1 
ATOM   6076 C  CA  . LEU   C 1 219 ? 23.195  -37.834 0.486   1.00 33.63  ? 205 LEU   L CA  1 
ATOM   6077 C  C   . LEU   C 1 219 ? 23.594  -37.826 -0.985  1.00 33.57  ? 205 LEU   L C   1 
ATOM   6078 O  O   . LEU   C 1 219 ? 23.334  -38.817 -1.679  1.00 31.70  ? 205 LEU   L O   1 
ATOM   6079 C  CB  . LEU   C 1 219 ? 24.187  -38.627 1.340   1.00 35.34  ? 205 LEU   L CB  1 
ATOM   6080 C  CG  . LEU   C 1 219 ? 25.261  -37.808 2.046   1.00 40.85  ? 205 LEU   L CG  1 
ATOM   6081 C  CD1 . LEU   C 1 219 ? 24.680  -36.809 3.039   1.00 38.65  ? 205 LEU   L CD1 1 
ATOM   6082 C  CD2 . LEU   C 1 219 ? 26.231  -38.745 2.763   1.00 45.33  ? 205 LEU   L CD2 1 
ATOM   6083 N  N   . HIS   C 1 220 ? 24.132  -36.707 -1.418  1.00 31.76  ? 206 HIS   L N   1 
ATOM   6084 C  CA  . HIS   C 1 220 ? 24.769  -36.575 -2.745  1.00 34.22  ? 206 HIS   L CA  1 
ATOM   6085 C  C   . HIS   C 1 220 ? 26.259  -36.362 -2.497  1.00 35.96  ? 206 HIS   L C   1 
ATOM   6086 O  O   . HIS   C 1 220 ? 26.648  -35.363 -1.862  1.00 36.75  ? 206 HIS   L O   1 
ATOM   6087 C  CB  . HIS   C 1 220 ? 24.165  -35.497 -3.648  1.00 36.75  ? 206 HIS   L CB  1 
ATOM   6088 C  CG  . HIS   C 1 220 ? 24.819  -35.611 -4.986  1.00 44.22  ? 206 HIS   L CG  1 
ATOM   6089 N  ND1 . HIS   C 1 220 ? 26.086  -35.056 -5.239  1.00 56.46  ? 206 HIS   L ND1 1 
ATOM   6090 C  CD2 . HIS   C 1 220 ? 24.546  -36.402 -6.045  1.00 48.31  ? 206 HIS   L CD2 1 
ATOM   6091 C  CE1 . HIS   C 1 220 ? 26.486  -35.419 -6.449  1.00 55.79  ? 206 HIS   L CE1 1 
ATOM   6092 N  NE2 . HIS   C 1 220 ? 25.544  -36.241 -6.961  1.00 49.88  ? 206 HIS   L NE2 1 
ATOM   6093 N  N   . VAL   C 1 221 ? 27.046  -37.345 -2.904  1.00 37.49  ? 207 VAL   L N   1 
ATOM   6094 C  CA  . VAL   C 1 221 ? 28.519  -37.310 -2.723  1.00 36.28  ? 207 VAL   L CA  1 
ATOM   6095 C  C   . VAL   C 1 221 ? 29.183  -37.162 -4.093  1.00 33.74  ? 207 VAL   L C   1 
ATOM   6096 O  O   . VAL   C 1 221 ? 28.901  -37.986 -4.993  1.00 35.44  ? 207 VAL   L O   1 
ATOM   6097 C  CB  . VAL   C 1 221 ? 28.986  -38.584 -1.986  1.00 40.27  ? 207 VAL   L CB  1 
ATOM   6098 C  CG1 . VAL   C 1 221 ? 30.500  -38.573 -1.780  1.00 41.16  ? 207 VAL   L CG1 1 
ATOM   6099 C  CG2 . VAL   C 1 221 ? 28.286  -38.699 -0.627  1.00 41.56  ? 207 VAL   L CG2 1 
ATOM   6100 N  N   . GLU   C 1 222 ? 30.093  -36.207 -4.211  1.00 32.89  ? 208 GLU   L N   1 
ATOM   6101 C  CA  . GLU   C 1 222 ? 30.903  -36.008 -5.447  1.00 39.26  ? 208 GLU   L CA  1 
ATOM   6102 C  C   . GLU   C 1 222 ? 32.351  -36.443 -5.111  1.00 37.27  ? 208 GLU   L C   1 
ATOM   6103 O  O   . GLU   C 1 222 ? 33.047  -35.701 -4.405  1.00 35.71  ? 208 GLU   L O   1 
ATOM   6104 C  CB  . GLU   C 1 222 ? 30.790  -34.561 -5.945  1.00 38.04  ? 208 GLU   L CB  1 
ATOM   6105 C  CG  . GLU   C 1 222 ? 31.393  -34.360 -7.331  1.00 48.72  ? 208 GLU   L CG  1 
ATOM   6106 C  CD  . GLU   C 1 222 ? 30.711  -35.112 -8.474  1.00 52.56  ? 208 GLU   L CD  1 
ATOM   6107 O  OE1 . GLU   C 1 222 ? 29.473  -35.230 -8.450  1.00 57.37  ? 208 GLU   L OE1 1 
ATOM   6108 O  OE2 . GLU   C 1 222 ? 31.426  -35.572 -9.398  1.00 57.95  ? 208 GLU   L OE2 1 
ATOM   6109 N  N   . LEU   C 1 223 ? 32.773  -37.603 -5.583  1.00 40.28  ? 209 LEU   L N   1 
ATOM   6110 C  CA  . LEU   C 1 223 ? 34.166  -38.091 -5.352  1.00 42.83  ? 209 LEU   L CA  1 
ATOM   6111 C  C   . LEU   C 1 223 ? 35.016  -37.754 -6.577  1.00 41.67  ? 209 LEU   L C   1 
ATOM   6112 O  O   . LEU   C 1 223 ? 34.569  -37.966 -7.687  1.00 41.35  ? 209 LEU   L O   1 
ATOM   6113 C  CB  . LEU   C 1 223 ? 34.170  -39.604 -5.116  1.00 42.55  ? 209 LEU   L CB  1 
ATOM   6114 C  CG  . LEU   C 1 223 ? 33.466  -40.104 -3.850  1.00 44.10  ? 209 LEU   L CG  1 
ATOM   6115 C  CD1 . LEU   C 1 223 ? 33.436  -41.610 -3.850  1.00 44.58  ? 209 LEU   L CD1 1 
ATOM   6116 C  CD2 . LEU   C 1 223 ? 34.138  -39.588 -2.597  1.00 46.76  ? 209 LEU   L CD2 1 
ATOM   6117 N  N   . PRO   C 1 224 ? 36.285  -37.324 -6.410  1.00 43.13  ? 210 PRO   L N   1 
ATOM   6118 C  CA  . PRO   C 1 224 ? 37.160  -36.995 -7.543  1.00 51.42  ? 210 PRO   L CA  1 
ATOM   6119 C  C   . PRO   C 1 224 ? 37.362  -38.119 -8.566  1.00 47.64  ? 210 PRO   L C   1 
ATOM   6120 O  O   . PRO   C 1 224 ? 37.353  -37.806 -9.732  1.00 48.27  ? 210 PRO   L O   1 
ATOM   6121 C  CB  . PRO   C 1 224 ? 38.529  -36.718 -6.910  1.00 50.72  ? 210 PRO   L CB  1 
ATOM   6122 C  CG  . PRO   C 1 224 ? 38.212  -36.393 -5.457  1.00 51.83  ? 210 PRO   L CG  1 
ATOM   6123 C  CD  . PRO   C 1 224 ? 36.926  -37.111 -5.107  1.00 50.17  ? 210 PRO   L CD  1 
ATOM   6124 N  N   . GLU   C 1 225 ? 37.482  -39.386 -8.129  1.00 45.28  ? 211 GLU   L N   1 
ATOM   6125 C  CA  . GLU   C 1 225 ? 37.722  -40.511 -9.067  1.00 50.12  ? 211 GLU   L CA  1 
ATOM   6126 C  C   . GLU   C 1 225 ? 36.387  -41.122 -9.505  1.00 47.86  ? 211 GLU   L C   1 
ATOM   6127 O  O   . GLU   C 1 225 ? 36.221  -41.400 -10.685 1.00 46.62  ? 211 GLU   L O   1 
ATOM   6128 C  CB  . GLU   C 1 225 ? 38.657  -41.580 -8.472  1.00 57.24  ? 211 GLU   L CB  1 
ATOM   6129 C  CG  . GLU   C 1 225 ? 40.067  -41.084 -8.194  1.00 85.56  ? 211 GLU   L CG  1 
ATOM   6130 C  CD  . GLU   C 1 225 ? 40.975  -40.839 -9.400  1.00 102.66 ? 211 GLU   L CD  1 
ATOM   6131 O  OE1 . GLU   C 1 225 ? 42.200  -41.064 -9.244  1.00 106.27 ? 211 GLU   L OE1 1 
ATOM   6132 O  OE2 . GLU   C 1 225 ? 40.479  -40.412 -10.487 1.00 98.17  ? 211 GLU   L OE2 1 
ATOM   6133 N  N   . THR   C 1 226 ? 35.487  -41.403 -8.574  1.00 40.28  ? 212 THR   L N   1 
ATOM   6134 C  CA  . THR   C 1 226 ? 34.272  -42.207 -8.834  1.00 41.96  ? 212 THR   L CA  1 
ATOM   6135 C  C   . THR   C 1 226 ? 33.179  -41.302 -9.447  1.00 37.33  ? 212 THR   L C   1 
ATOM   6136 O  O   . THR   C 1 226 ? 32.311  -41.832 -10.175 1.00 40.08  ? 212 THR   L O   1 
ATOM   6137 C  CB  . THR   C 1 226 ? 33.831  -42.915 -7.543  1.00 45.73  ? 212 THR   L CB  1 
ATOM   6138 O  OG1 . THR   C 1 226 ? 34.874  -43.767 -7.038  1.00 50.62  ? 212 THR   L OG1 1 
ATOM   6139 C  CG2 . THR   C 1 226 ? 32.601  -43.765 -7.748  1.00 43.23  ? 212 THR   L CG2 1 
ATOM   6140 N  N   . GLY   C 1 227 ? 33.234  -39.993 -9.199  1.00 39.10  ? 213 GLY   L N   1 
ATOM   6141 C  CA  . GLY   C 1 227 ? 32.192  -39.031 -9.616  1.00 39.09  ? 213 GLY   L CA  1 
ATOM   6142 C  C   . GLY   C 1 227 ? 31.030  -39.060 -8.636  1.00 40.26  ? 213 GLY   L C   1 
ATOM   6143 O  O   . GLY   C 1 227 ? 31.270  -39.197 -7.415  1.00 40.80  ? 213 GLY   L O   1 
ATOM   6144 N  N   . GLY   C 1 228 ? 29.786  -38.932 -9.123  1.00 41.18  ? 214 GLY   L N   1 
ATOM   6145 C  CA  . GLY   C 1 228 ? 28.634  -38.659 -8.253  1.00 37.32  ? 214 GLY   L CA  1 
ATOM   6146 C  C   . GLY   C 1 228 ? 27.945  -39.928 -7.739  1.00 35.23  ? 214 GLY   L C   1 
ATOM   6147 O  O   . GLY   C 1 228 ? 27.765  -40.903 -8.509  1.00 33.64  ? 214 GLY   L O   1 
ATOM   6148 N  N   . ILE   C 1 229 ? 27.516  -39.901 -6.477  1.00 32.93  ? 215 ILE   L N   1 
ATOM   6149 C  CA  . ILE   C 1 229 ? 26.756  -41.008 -5.849  1.00 36.31  ? 215 ILE   L CA  1 
ATOM   6150 C  C   . ILE   C 1 229 ? 25.588  -40.392 -5.075  1.00 33.43  ? 215 ILE   L C   1 
ATOM   6151 O  O   . ILE   C 1 229 ? 25.839  -39.519 -4.220  1.00 35.70  ? 215 ILE   L O   1 
ATOM   6152 C  CB  . ILE   C 1 229 ? 27.659  -41.826 -4.907  1.00 35.67  ? 215 ILE   L CB  1 
ATOM   6153 C  CG1 . ILE   C 1 229 ? 28.904  -42.390 -5.614  1.00 38.39  ? 215 ILE   L CG1 1 
ATOM   6154 C  CG2 . ILE   C 1 229 ? 26.835  -42.908 -4.223  1.00 39.68  ? 215 ILE   L CG2 1 
ATOM   6155 C  CD1 . ILE   C 1 229 ? 29.895  -43.052 -4.662  1.00 41.47  ? 215 ILE   L CD1 1 
ATOM   6156 N  N   . ILE   C 1 230 ? 24.384  -40.909 -5.322  1.00 34.01  ? 216 ILE   L N   1 
ATOM   6157 C  CA  . ILE   C 1 230 ? 23.191  -40.628 -4.489  1.00 35.81  ? 216 ILE   L CA  1 
ATOM   6158 C  C   . ILE   C 1 230 ? 22.933  -41.818 -3.568  1.00 31.57  ? 216 ILE   L C   1 
ATOM   6159 O  O   . ILE   C 1 230 ? 22.685  -42.917 -4.060  1.00 34.47  ? 216 ILE   L O   1 
ATOM   6160 C  CB  . ILE   C 1 230 ? 21.987  -40.287 -5.379  1.00 35.71  ? 216 ILE   L CB  1 
ATOM   6161 C  CG1 . ILE   C 1 230 ? 22.289  -39.079 -6.261  1.00 39.51  ? 216 ILE   L CG1 1 
ATOM   6162 C  CG2 . ILE   C 1 230 ? 20.766  -40.052 -4.535  1.00 35.80  ? 216 ILE   L CG2 1 
ATOM   6163 C  CD1 . ILE   C 1 230 ? 21.299  -38.917 -7.428  1.00 42.89  ? 216 ILE   L CD1 1 
ATOM   6164 N  N   . LEU   C 1 231 ? 22.954  -41.578 -2.253  1.00 33.77  ? 217 LEU   L N   1 
ATOM   6165 C  CA  . LEU   C 1 231 ? 22.476  -42.548 -1.251  1.00 33.74  ? 217 LEU   L CA  1 
ATOM   6166 C  C   . LEU   C 1 231 ? 21.000  -42.274 -1.039  1.00 32.76  ? 217 LEU   L C   1 
ATOM   6167 O  O   . LEU   C 1 231 ? 20.658  -41.203 -0.494  1.00 32.24  ? 217 LEU   L O   1 
ATOM   6168 C  CB  . LEU   C 1 231 ? 23.284  -42.416 0.038   1.00 35.49  ? 217 LEU   L CB  1 
ATOM   6169 C  CG  . LEU   C 1 231 ? 24.800  -42.460 -0.157  1.00 37.41  ? 217 LEU   L CG  1 
ATOM   6170 C  CD1 . LEU   C 1 231 ? 25.491  -42.374 1.172   1.00 40.90  ? 217 LEU   L CD1 1 
ATOM   6171 C  CD2 . LEU   C 1 231 ? 25.243  -43.714 -0.933  1.00 35.16  ? 217 LEU   L CD2 1 
ATOM   6172 N  N   . ALA   C 1 232 ? 20.175  -43.159 -1.567  1.00 31.93  ? 218 ALA   L N   1 
ATOM   6173 C  CA  . ALA   C 1 232 ? 18.701  -43.019 -1.564  1.00 37.04  ? 218 ALA   L CA  1 
ATOM   6174 C  C   . ALA   C 1 232 ? 18.094  -43.605 -0.276  1.00 36.40  ? 218 ALA   L C   1 
ATOM   6175 O  O   . ALA   C 1 232 ? 16.925  -43.250 0.071   1.00 33.17  ? 218 ALA   L O   1 
ATOM   6176 C  CB  . ALA   C 1 232 ? 18.156  -43.705 -2.783  1.00 37.88  ? 218 ALA   L CB  1 
ATOM   6177 N  N   . SER   C 1 233 ? 18.791  -44.551 0.361   1.00 33.60  ? 219 SER   L N   1 
ATOM   6178 C  CA  . SER   C 1 233 ? 18.230  -45.378 1.451   1.00 36.02  ? 219 SER   L CA  1 
ATOM   6179 C  C   . SER   C 1 233 ? 16.829  -45.915 1.062   1.00 37.84  ? 219 SER   L C   1 
ATOM   6180 O  O   . SER   C 1 233 ? 16.643  -46.353 -0.089  1.00 32.72  ? 219 SER   L O   1 
ATOM   6181 C  CB  . SER   C 1 233 ? 18.205  -44.570 2.730   1.00 37.18  ? 219 SER   L CB  1 
ATOM   6182 O  OG  . SER   C 1 233 ? 17.684  -45.341 3.803   1.00 35.68  ? 219 SER   L OG  1 
ATOM   6183 N  N   . ASP   C 1 234 ? 15.838  -45.825 1.953   1.00 36.06  ? 220 ASP   L N   1 
ATOM   6184 C  CA  . ASP   C 1 234 ? 14.485  -46.398 1.688   1.00 35.87  ? 220 ASP   L CA  1 
ATOM   6185 C  C   . ASP   C 1 234 ? 13.596  -45.482 0.841   1.00 34.17  ? 220 ASP   L C   1 
ATOM   6186 O  O   . ASP   C 1 234 ? 12.443  -45.887 0.623   1.00 33.89  ? 220 ASP   L O   1 
ATOM   6187 C  CB  . ASP   C 1 234 ? 13.771  -46.827 2.968   1.00 32.92  ? 220 ASP   L CB  1 
ATOM   6188 C  CG  . ASP   C 1 234 ? 14.433  -48.047 3.607   1.00 37.09  ? 220 ASP   L CG  1 
ATOM   6189 O  OD1 . ASP   C 1 234 ? 15.391  -48.626 2.982   1.00 37.40  ? 220 ASP   L OD1 1 
ATOM   6190 O  OD2 . ASP   C 1 234 ? 14.062  -48.307 4.731   1.00 37.42  ? 220 ASP   L OD2 1 
ATOM   6191 N  N   . ALA   C 1 235 ? 14.088  -44.353 0.334   1.00 33.86  ? 221 ALA   L N   1 
ATOM   6192 C  CA  . ALA   C 1 235 ? 13.377  -43.639 -0.752  1.00 32.50  ? 221 ALA   L CA  1 
ATOM   6193 C  C   . ALA   C 1 235 ? 13.232  -44.600 -1.941  1.00 34.49  ? 221 ALA   L C   1 
ATOM   6194 O  O   . ALA   C 1 235 ? 12.250  -44.476 -2.684  1.00 33.96  ? 221 ALA   L O   1 
ATOM   6195 C  CB  . ALA   C 1 235 ? 14.088  -42.363 -1.127  1.00 30.14  ? 221 ALA   L CB  1 
ATOM   6196 N  N   . ILE   C 1 236 ? 14.172  -45.553 -2.110  1.00 34.10  ? 222 ILE   L N   1 
ATOM   6197 C  CA  . ILE   C 1 236 ? 14.132  -46.560 -3.206  1.00 33.67  ? 222 ILE   L CA  1 
ATOM   6198 C  C   . ILE   C 1 236 ? 14.730  -47.873 -2.705  1.00 37.54  ? 222 ILE   L C   1 
ATOM   6199 O  O   . ILE   C 1 236 ? 15.962  -47.997 -2.579  1.00 32.99  ? 222 ILE   L O   1 
ATOM   6200 C  CB  . ILE   C 1 236 ? 14.879  -46.100 -4.478  1.00 36.80  ? 222 ILE   L CB  1 
ATOM   6201 C  CG1 . ILE   C 1 236 ? 14.596  -44.645 -4.864  1.00 35.69  ? 222 ILE   L CG1 1 
ATOM   6202 C  CG2 . ILE   C 1 236 ? 14.572  -47.072 -5.622  1.00 38.65  ? 222 ILE   L CG2 1 
ATOM   6203 C  CD1 . ILE   C 1 236 ? 15.523  -44.124 -5.960  1.00 37.22  ? 222 ILE   L CD1 1 
ATOM   6204 N  N   . TYR   C 1 237 ? 13.883  -48.847 -2.443  1.00 35.41  ? 223 TYR   L N   1 
ATOM   6205 C  CA  . TYR   C 1 237 ? 14.320  -50.136 -1.879  1.00 37.05  ? 223 TYR   L CA  1 
ATOM   6206 C  C   . TYR   C 1 237 ? 15.300  -50.857 -2.839  1.00 38.08  ? 223 TYR   L C   1 
ATOM   6207 O  O   . TYR   C 1 237 ? 16.376  -51.319 -2.370  1.00 36.45  ? 223 TYR   L O   1 
ATOM   6208 C  CB  . TYR   C 1 237 ? 13.075  -50.981 -1.637  1.00 36.57  ? 223 TYR   L CB  1 
ATOM   6209 C  CG  . TYR   C 1 237 ? 12.401  -50.883 -0.299  1.00 33.87  ? 223 TYR   L CG  1 
ATOM   6210 C  CD1 . TYR   C 1 237 ? 13.062  -50.473 0.835   1.00 34.20  ? 223 TYR   L CD1 1 
ATOM   6211 C  CD2 . TYR   C 1 237 ? 11.082  -51.297 -0.170  1.00 36.06  ? 223 TYR   L CD2 1 
ATOM   6212 C  CE1 . TYR   C 1 237 ? 12.438  -50.462 2.078   1.00 35.59  ? 223 TYR   L CE1 1 
ATOM   6213 C  CE2 . TYR   C 1 237 ? 10.445  -51.305 1.064   1.00 39.25  ? 223 TYR   L CE2 1 
ATOM   6214 C  CZ  . TYR   C 1 237 ? 11.138  -50.909 2.199   1.00 35.56  ? 223 TYR   L CZ  1 
ATOM   6215 O  OH  . TYR   C 1 237 ? 10.520  -50.946 3.405   1.00 37.85  ? 223 TYR   L OH  1 
ATOM   6216 N  N   . THR   C 1 238 ? 14.907  -51.037 -4.107  1.00 33.49  ? 224 THR   L N   1 
ATOM   6217 C  CA  . THR   C 1 238 ? 15.609  -51.906 -5.088  1.00 37.93  ? 224 THR   L CA  1 
ATOM   6218 C  C   . THR   C 1 238 ? 15.477  -51.317 -6.498  1.00 40.29  ? 224 THR   L C   1 
ATOM   6219 O  O   . THR   C 1 238 ? 14.705  -50.388 -6.706  1.00 39.49  ? 224 THR   L O   1 
ATOM   6220 C  CB  . THR   C 1 238 ? 15.041  -53.338 -5.087  1.00 40.51  ? 224 THR   L CB  1 
ATOM   6221 O  OG1 . THR   C 1 238 ? 13.728  -53.280 -5.646  1.00 38.69  ? 224 THR   L OG1 1 
ATOM   6222 C  CG2 . THR   C 1 238 ? 14.944  -53.984 -3.723  1.00 41.64  ? 224 THR   L CG2 1 
ATOM   6223 N  N   . ALA   C 1 239 ? 16.169  -51.921 -7.457  1.00 38.92  ? 225 ALA   L N   1 
ATOM   6224 C  CA  . ALA   C 1 239 ? 16.092  -51.612 -8.898  1.00 41.17  ? 225 ALA   L CA  1 
ATOM   6225 C  C   . ALA   C 1 239 ? 14.661  -51.873 -9.374  1.00 36.80  ? 225 ALA   L C   1 
ATOM   6226 O  O   . ALA   C 1 239 ? 14.213  -51.165 -10.297 1.00 39.46  ? 225 ALA   L O   1 
ATOM   6227 C  CB  . ALA   C 1 239 ? 17.167  -52.404 -9.672  1.00 39.63  ? 225 ALA   L CB  1 
ATOM   6228 N  N   . GLU   C 1 240 ? 13.989  -52.872 -8.819  1.00 39.38  ? 226 GLU   L N   1 
ATOM   6229 C  CA  . GLU   C 1 240 ? 12.586  -53.212 -9.175  1.00 39.62  ? 226 GLU   L CA  1 
ATOM   6230 C  C   . GLU   C 1 240 ? 11.665  -52.033 -8.755  1.00 40.23  ? 226 GLU   L C   1 
ATOM   6231 O  O   . GLU   C 1 240 ? 10.819  -51.593 -9.575  1.00 39.68  ? 226 GLU   L O   1 
ATOM   6232 C  CB  . GLU   C 1 240 ? 12.240  -54.561 -8.534  1.00 44.49  ? 226 GLU   L CB  1 
ATOM   6233 C  CG  . GLU   C 1 240 ? 10.849  -55.046 -8.885  1.00 47.99  ? 226 GLU   L CG  1 
ATOM   6234 C  CD  . GLU   C 1 240 ? 10.369  -56.366 -8.295  1.00 55.34  ? 226 GLU   L CD  1 
ATOM   6235 O  OE1 . GLU   C 1 240 ? 11.069  -56.977 -7.450  1.00 50.84  ? 226 GLU   L OE1 1 
ATOM   6236 O  OE2 . GLU   C 1 240 ? 9.264   -56.775 -8.689  1.00 55.93  ? 226 GLU   L OE2 1 
ATOM   6237 N  N   . SER   C 1 241 ? 11.871  -51.467 -7.550  1.00 38.47  ? 227 SER   L N   1 
ATOM   6238 C  CA  . SER   C 1 241 ? 11.184  -50.228 -7.078  1.00 38.50  ? 227 SER   L CA  1 
ATOM   6239 C  C   . SER   C 1 241 ? 11.378  -49.110 -8.114  1.00 35.75  ? 227 SER   L C   1 
ATOM   6240 O  O   . SER   C 1 241 ? 10.395  -48.394 -8.473  1.00 35.81  ? 227 SER   L O   1 
ATOM   6241 C  CB  . SER   C 1 241 ? 11.675  -49.793 -5.691  1.00 34.80  ? 227 SER   L CB  1 
ATOM   6242 O  OG  . SER   C 1 241 ? 11.797  -50.906 -4.802  1.00 33.60  ? 227 SER   L OG  1 
ATOM   6243 N  N   . TYR   C 1 242 ? 12.619  -48.920 -8.547  1.00 34.00  ? 228 TYR   L N   1 
ATOM   6244 C  CA  . TYR   C 1 242 ? 13.062  -47.777 -9.380  1.00 36.79  ? 228 TYR   L CA  1 
ATOM   6245 C  C   . TYR   C 1 242 ? 12.496  -47.876 -10.801 1.00 37.80  ? 228 TYR   L C   1 
ATOM   6246 O  O   . TYR   C 1 242 ? 12.172  -46.790 -11.367 1.00 38.30  ? 228 TYR   L O   1 
ATOM   6247 C  CB  . TYR   C 1 242 ? 14.584  -47.741 -9.420  1.00 34.94  ? 228 TYR   L CB  1 
ATOM   6248 C  CG  . TYR   C 1 242 ? 15.239  -46.468 -9.859  1.00 38.92  ? 228 TYR   L CG  1 
ATOM   6249 C  CD1 . TYR   C 1 242 ? 14.895  -45.236 -9.332  1.00 38.64  ? 228 TYR   L CD1 1 
ATOM   6250 C  CD2 . TYR   C 1 242 ? 16.251  -46.498 -10.815 1.00 38.15  ? 228 TYR   L CD2 1 
ATOM   6251 C  CE1 . TYR   C 1 242 ? 15.552  -44.081 -9.735  1.00 40.01  ? 228 TYR   L CE1 1 
ATOM   6252 C  CE2 . TYR   C 1 242 ? 16.939  -45.357 -11.189 1.00 38.45  ? 228 TYR   L CE2 1 
ATOM   6253 C  CZ  . TYR   C 1 242 ? 16.599  -44.141 -10.637 1.00 41.79  ? 228 TYR   L CZ  1 
ATOM   6254 O  OH  . TYR   C 1 242 ? 17.295  -43.025 -11.006 1.00 39.45  ? 228 TYR   L OH  1 
ATOM   6255 N  N   . GLY   C 1 243 ? 12.335  -49.091 -11.359 1.00 38.85  ? 229 GLY   L N   1 
ATOM   6256 C  CA  . GLY   C 1 243 ? 11.894  -49.267 -12.768 1.00 42.39  ? 229 GLY   L CA  1 
ATOM   6257 C  C   . GLY   C 1 243 ? 12.675  -48.342 -13.714 1.00 41.50  ? 229 GLY   L C   1 
ATOM   6258 O  O   . GLY   C 1 243 ? 13.910  -48.292 -13.622 1.00 42.89  ? 229 GLY   L O   1 
ATOM   6259 N  N   . PRO   C 1 244 ? 12.044  -47.521 -14.592 1.00 43.00  ? 230 PRO   L N   1 
ATOM   6260 C  CA  . PRO   C 1 244 ? 10.597  -47.294 -14.616 1.00 48.35  ? 230 PRO   L CA  1 
ATOM   6261 C  C   . PRO   C 1 244 ? 9.820   -48.442 -15.250 1.00 48.97  ? 230 PRO   L C   1 
ATOM   6262 O  O   . PRO   C 1 244 ? 10.378  -49.204 -16.023 1.00 57.50  ? 230 PRO   L O   1 
ATOM   6263 C  CB  . PRO   C 1 244 ? 10.404  -45.994 -15.425 1.00 52.73  ? 230 PRO   L CB  1 
ATOM   6264 C  CG  . PRO   C 1 244 ? 11.679  -45.830 -16.243 1.00 54.68  ? 230 PRO   L CG  1 
ATOM   6265 C  CD  . PRO   C 1 244 ? 12.746  -46.703 -15.595 1.00 48.69  ? 230 PRO   L CD  1 
ATOM   6266 N  N   . PRO   C 1 245 ? 8.523   -48.627 -14.932 1.00 48.73  ? 231 PRO   L N   1 
ATOM   6267 C  CA  . PRO   C 1 245 ? 7.779   -47.708 -14.080 1.00 48.25  ? 231 PRO   L CA  1 
ATOM   6268 C  C   . PRO   C 1 245 ? 8.028   -48.018 -12.595 1.00 43.74  ? 231 PRO   L C   1 
ATOM   6269 O  O   . PRO   C 1 245 ? 8.543   -49.067 -12.271 1.00 40.21  ? 231 PRO   L O   1 
ATOM   6270 C  CB  . PRO   C 1 245 ? 6.330   -47.994 -14.509 1.00 50.83  ? 231 PRO   L CB  1 
ATOM   6271 C  CG  . PRO   C 1 245 ? 6.333   -49.497 -14.766 1.00 56.71  ? 231 PRO   L CG  1 
ATOM   6272 C  CD  . PRO   C 1 245 ? 7.712   -49.792 -15.332 1.00 55.92  ? 231 PRO   L CD  1 
ATOM   6273 N  N   . ILE   C 1 246 ? 7.650   -47.098 -11.714 1.00 43.02  ? 232 ILE   L N   1 
ATOM   6274 C  CA  . ILE   C 1 246 ? 7.917   -47.231 -10.254 1.00 39.52  ? 232 ILE   L CA  1 
ATOM   6275 C  C   . ILE   C 1 246 ? 7.049   -48.364 -9.694  1.00 40.50  ? 232 ILE   L C   1 
ATOM   6276 O  O   . ILE   C 1 246 ? 5.899   -48.417 -10.030 1.00 44.23  ? 232 ILE   L O   1 
ATOM   6277 C  CB  . ILE   C 1 246 ? 7.683   -45.901 -9.529  1.00 40.56  ? 232 ILE   L CB  1 
ATOM   6278 C  CG1 . ILE   C 1 246 ? 8.598   -44.797 -10.056 1.00 38.86  ? 232 ILE   L CG1 1 
ATOM   6279 C  CG2 . ILE   C 1 246 ? 7.836   -46.107 -8.027  1.00 39.74  ? 232 ILE   L CG2 1 
ATOM   6280 C  CD1 . ILE   C 1 246 ? 8.156   -43.414 -9.669  1.00 43.50  ? 232 ILE   L CD1 1 
ATOM   6281 N  N   . LYS   C 1 247 ? 7.597   -49.231 -8.856  1.00 40.85  ? 233 LYS   L N   1 
ATOM   6282 C  CA  . LYS   C 1 247 ? 6.815   -50.224 -8.076  1.00 43.26  ? 233 LYS   L CA  1 
ATOM   6283 C  C   . LYS   C 1 247 ? 6.921   -49.850 -6.603  1.00 42.72  ? 233 LYS   L C   1 
ATOM   6284 O  O   . LYS   C 1 247 ? 7.924   -50.146 -5.940  1.00 40.27  ? 233 LYS   L O   1 
ATOM   6285 C  CB  . LYS   C 1 247 ? 7.320   -51.632 -8.375  1.00 43.99  ? 233 LYS   L CB  1 
ATOM   6286 C  CG  . LYS   C 1 247 ? 7.232   -52.027 -9.844  1.00 47.73  ? 233 LYS   L CG  1 
ATOM   6287 C  CD  . LYS   C 1 247 ? 6.864   -53.499 -10.014 1.00 59.39  ? 233 LYS   L CD  1 
ATOM   6288 C  CE  . LYS   C 1 247 ? 7.176   -54.071 -11.378 1.00 69.27  ? 233 LYS   L CE  1 
ATOM   6289 N  NZ  . LYS   C 1 247 ? 7.411   -55.534 -11.282 1.00 68.93  ? 233 LYS   L NZ  1 
ATOM   6290 N  N   . PRO   C 1 248 ? 5.910   -49.160 -6.036  1.00 40.22  ? 234 PRO   L N   1 
ATOM   6291 C  CA  . PRO   C 1 248 ? 5.998   -48.734 -4.647  1.00 40.34  ? 234 PRO   L CA  1 
ATOM   6292 C  C   . PRO   C 1 248 ? 5.919   -49.880 -3.653  1.00 37.83  ? 234 PRO   L C   1 
ATOM   6293 O  O   . PRO   C 1 248 ? 5.436   -50.965 -3.996  1.00 39.23  ? 234 PRO   L O   1 
ATOM   6294 C  CB  . PRO   C 1 248 ? 4.754   -47.836 -4.471  1.00 39.86  ? 234 PRO   L CB  1 
ATOM   6295 C  CG  . PRO   C 1 248 ? 3.770   -48.414 -5.458  1.00 45.50  ? 234 PRO   L CG  1 
ATOM   6296 C  CD  . PRO   C 1 248 ? 4.607   -48.833 -6.652  1.00 43.37  ? 234 PRO   L CD  1 
ATOM   6297 N  N   . PRO   C 1 249 ? 6.398   -49.647 -2.411  1.00 38.93  ? 235 PRO   L N   1 
ATOM   6298 C  CA  . PRO   C 1 249 ? 6.298   -50.614 -1.322  1.00 41.72  ? 235 PRO   L CA  1 
ATOM   6299 C  C   . PRO   C 1 249 ? 4.878   -50.816 -0.771  1.00 47.39  ? 235 PRO   L C   1 
ATOM   6300 O  O   . PRO   C 1 249 ? 3.986   -50.031 -1.103  1.00 42.05  ? 235 PRO   L O   1 
ATOM   6301 C  CB  . PRO   C 1 249 ? 7.227   -50.023 -0.253  1.00 45.22  ? 235 PRO   L CB  1 
ATOM   6302 C  CG  . PRO   C 1 249 ? 7.227   -48.536 -0.527  1.00 43.07  ? 235 PRO   L CG  1 
ATOM   6303 C  CD  . PRO   C 1 249 ? 7.163   -48.439 -2.025  1.00 40.07  ? 235 PRO   L CD  1 
ATOM   6304 N  N   . GLY   C 1 250 ? 4.698   -51.893 0.009   1.00 42.00  ? 236 GLY   L N   1 
ATOM   6305 C  CA  . GLY   C 1 250 ? 3.378   -52.457 0.384   1.00 46.19  ? 236 GLY   L CA  1 
ATOM   6306 C  C   . GLY   C 1 250 ? 2.689   -51.630 1.444   1.00 52.57  ? 236 GLY   L C   1 
ATOM   6307 O  O   . GLY   C 1 250 ? 1.429   -51.726 1.594   1.00 56.85  ? 236 GLY   L O   1 
ATOM   6308 N  N   . ILE   C 1 251 ? 3.490   -50.908 2.219   1.00 47.29  ? 237 ILE   L N   1 
ATOM   6309 C  CA  . ILE   C 1 251 ? 2.988   -49.877 3.153   1.00 55.11  ? 237 ILE   L CA  1 
ATOM   6310 C  C   . ILE   C 1 251 ? 3.840   -48.619 2.917   1.00 62.17  ? 237 ILE   L C   1 
ATOM   6311 O  O   . ILE   C 1 251 ? 5.037   -48.715 2.555   1.00 54.95  ? 237 ILE   L O   1 
ATOM   6312 C  CB  . ILE   C 1 251 ? 3.018   -50.417 4.602   1.00 62.05  ? 237 ILE   L CB  1 
ATOM   6313 C  CG1 . ILE   C 1 251 ? 2.008   -49.706 5.517   1.00 66.45  ? 237 ILE   L CG1 1 
ATOM   6314 C  CG2 . ILE   C 1 251 ? 4.459   -50.411 5.133   1.00 64.77  ? 237 ILE   L CG2 1 
ATOM   6315 C  CD1 . ILE   C 1 251 ? 2.590   -48.599 6.391   1.00 73.48  ? 237 ILE   L CD1 1 
ATOM   6316 N  N   . ILE   C 1 252 ? 3.235   -47.454 3.095   1.00 55.45  ? 238 ILE   L N   1 
ATOM   6317 C  CA  . ILE   C 1 252 ? 3.911   -46.180 2.758   1.00 52.46  ? 238 ILE   L CA  1 
ATOM   6318 C  C   . ILE   C 1 252 ? 3.307   -45.118 3.658   1.00 46.96  ? 238 ILE   L C   1 
ATOM   6319 O  O   . ILE   C 1 252 ? 2.099   -45.168 3.844   1.00 54.01  ? 238 ILE   L O   1 
ATOM   6320 C  CB  . ILE   C 1 252 ? 3.627   -45.963 1.267   1.00 51.31  ? 238 ILE   L CB  1 
ATOM   6321 C  CG1 . ILE   C 1 252 ? 4.638   -45.056 0.580   1.00 48.82  ? 238 ILE   L CG1 1 
ATOM   6322 C  CG2 . ILE   C 1 252 ? 2.189   -45.496 1.057   1.00 63.42  ? 238 ILE   L CG2 1 
ATOM   6323 C  CD1 . ILE   C 1 252 ? 4.703   -45.358 -0.897  1.00 62.21  ? 238 ILE   L CD1 1 
ATOM   6324 N  N   . TYR   C 1 253 ? 4.071   -44.149 4.137   1.00 36.22  ? 239 TYR   L N   1 
ATOM   6325 C  CA  . TYR   C 1 253 ? 3.446   -43.036 4.885   1.00 35.44  ? 239 TYR   L CA  1 
ATOM   6326 C  C   . TYR   C 1 253 ? 2.731   -42.091 3.899   1.00 36.11  ? 239 TYR   L C   1 
ATOM   6327 O  O   . TYR   C 1 253 ? 1.539   -41.806 4.092   1.00 38.03  ? 239 TYR   L O   1 
ATOM   6328 C  CB  . TYR   C 1 253 ? 4.440   -42.286 5.774   1.00 34.97  ? 239 TYR   L CB  1 
ATOM   6329 C  CG  . TYR   C 1 253 ? 3.838   -41.040 6.361   1.00 34.92  ? 239 TYR   L CG  1 
ATOM   6330 C  CD1 . TYR   C 1 253 ? 2.771   -41.104 7.260   1.00 37.74  ? 239 TYR   L CD1 1 
ATOM   6331 C  CD2 . TYR   C 1 253 ? 4.289   -39.788 5.978   1.00 34.14  ? 239 TYR   L CD2 1 
ATOM   6332 C  CE1 . TYR   C 1 253 ? 2.198   -39.953 7.802   1.00 35.82  ? 239 TYR   L CE1 1 
ATOM   6333 C  CE2 . TYR   C 1 253 ? 3.737   -38.635 6.512   1.00 33.17  ? 239 TYR   L CE2 1 
ATOM   6334 C  CZ  . TYR   C 1 253 ? 2.698   -38.716 7.422   1.00 34.36  ? 239 TYR   L CZ  1 
ATOM   6335 O  OH  . TYR   C 1 253 ? 2.179   -37.549 7.877   1.00 38.76  ? 239 TYR   L OH  1 
ATOM   6336 N  N   . ASP   C 1 254 ? 3.448   -41.561 2.898   1.00 33.70  ? 240 ASP   L N   1 
ATOM   6337 C  CA  . ASP   C 1 254 ? 2.938   -40.516 1.977   1.00 35.75  ? 240 ASP   L CA  1 
ATOM   6338 C  C   . ASP   C 1 254 ? 3.146   -41.018 0.548   1.00 34.59  ? 240 ASP   L C   1 
ATOM   6339 O  O   . ASP   C 1 254 ? 4.252   -40.877 0.036   1.00 35.08  ? 240 ASP   L O   1 
ATOM   6340 C  CB  . ASP   C 1 254 ? 3.705   -39.220 2.216   1.00 34.02  ? 240 ASP   L CB  1 
ATOM   6341 C  CG  . ASP   C 1 254 ? 3.389   -38.087 1.270   1.00 36.94  ? 240 ASP   L CG  1 
ATOM   6342 O  OD1 . ASP   C 1 254 ? 2.446   -38.207 0.469   1.00 33.81  ? 240 ASP   L OD1 1 
ATOM   6343 O  OD2 . ASP   C 1 254 ? 4.147   -37.110 1.303   1.00 35.86  ? 240 ASP   L OD2 1 
ATOM   6344 N  N   . SER   C 1 255 ? 2.168   -41.679 -0.047  1.00 34.85  ? 241 SER   L N   1 
ATOM   6345 C  CA  . SER   C 1 255 ? 2.347   -42.295 -1.386  1.00 33.55  ? 241 SER   L CA  1 
ATOM   6346 C  C   . SER   C 1 255 ? 2.760   -41.222 -2.402  1.00 33.95  ? 241 SER   L C   1 
ATOM   6347 O  O   . SER   C 1 255 ? 3.612   -41.511 -3.245  1.00 35.15  ? 241 SER   L O   1 
ATOM   6348 C  CB  . SER   C 1 255 ? 1.108   -43.035 -1.827  1.00 35.50  ? 241 SER   L CB  1 
ATOM   6349 O  OG  . SER   C 1 255 ? -0.033  -42.193 -1.783  1.00 33.66  ? 241 SER   L OG  1 
ATOM   6350 N  N   . LEU   C 1 256 ? 2.130   -40.047 -2.391  1.00 31.77  ? 242 LEU   L N   1 
ATOM   6351 C  CA  . LEU   C 1 256 ? 2.410   -38.986 -3.394  1.00 34.51  ? 242 LEU   L CA  1 
ATOM   6352 C  C   . LEU   C 1 256 ? 3.862   -38.538 -3.222  1.00 33.87  ? 242 LEU   L C   1 
ATOM   6353 O  O   . LEU   C 1 256 ? 4.577   -38.417 -4.244  1.00 31.09  ? 242 LEU   L O   1 
ATOM   6354 C  CB  . LEU   C 1 256 ? 1.454   -37.791 -3.245  1.00 34.61  ? 242 LEU   L CB  1 
ATOM   6355 C  CG  . LEU   C 1 256 ? -0.021  -38.048 -3.574  1.00 39.74  ? 242 LEU   L CG  1 
ATOM   6356 C  CD1 . LEU   C 1 256 ? -0.821  -36.734 -3.517  1.00 38.00  ? 242 LEU   L CD1 1 
ATOM   6357 C  CD2 . LEU   C 1 256 ? -0.173  -38.664 -4.955  1.00 42.04  ? 242 LEU   L CD2 1 
ATOM   6358 N  N   . GLY   C 1 257 ? 4.268   -38.243 -1.978  1.00 32.65  ? 243 GLY   L N   1 
ATOM   6359 C  CA  . GLY   C 1 257 ? 5.652   -37.830 -1.695  1.00 34.07  ? 243 GLY   L CA  1 
ATOM   6360 C  C   . GLY   C 1 257 ? 6.626   -38.920 -2.140  1.00 33.63  ? 243 GLY   L C   1 
ATOM   6361 O  O   . GLY   C 1 257 ? 7.657   -38.578 -2.647  1.00 32.60  ? 243 GLY   L O   1 
ATOM   6362 N  N   . TYR   C 1 258 ? 6.285   -40.194 -1.948  1.00 32.86  ? 244 TYR   L N   1 
ATOM   6363 C  CA  . TYR   C 1 258 ? 7.156   -41.341 -2.315  1.00 35.48  ? 244 TYR   L CA  1 
ATOM   6364 C  C   . TYR   C 1 258 ? 7.404   -41.288 -3.831  1.00 37.05  ? 244 TYR   L C   1 
ATOM   6365 O  O   . TYR   C 1 258 ? 8.559   -41.244 -4.274  1.00 34.23  ? 244 TYR   L O   1 
ATOM   6366 C  CB  . TYR   C 1 258 ? 6.557   -42.677 -1.859  1.00 32.83  ? 244 TYR   L CB  1 
ATOM   6367 C  CG  . TYR   C 1 258 ? 7.314   -43.853 -2.413  1.00 34.79  ? 244 TYR   L CG  1 
ATOM   6368 C  CD1 . TYR   C 1 258 ? 8.422   -44.371 -1.750  1.00 31.57  ? 244 TYR   L CD1 1 
ATOM   6369 C  CD2 . TYR   C 1 258 ? 7.003   -44.358 -3.660  1.00 33.97  ? 244 TYR   L CD2 1 
ATOM   6370 C  CE1 . TYR   C 1 258 ? 9.163   -45.397 -2.306  1.00 34.91  ? 244 TYR   L CE1 1 
ATOM   6371 C  CE2 . TYR   C 1 258 ? 7.735   -45.392 -4.217  1.00 35.52  ? 244 TYR   L CE2 1 
ATOM   6372 C  CZ  . TYR   C 1 258 ? 8.823   -45.905 -3.544  1.00 34.15  ? 244 TYR   L CZ  1 
ATOM   6373 O  OH  . TYR   C 1 258 ? 9.560   -46.911 -4.096  1.00 36.60  ? 244 TYR   L OH  1 
ATOM   6374 N  N   . MET   C 1 259 ? 6.319   -41.224 -4.612  1.00 34.15  ? 245 MET   L N   1 
ATOM   6375 C  CA  . MET   C 1 259 ? 6.388   -41.213 -6.099  1.00 33.34  ? 245 MET   L CA  1 
ATOM   6376 C  C   . MET   C 1 259 ? 7.177   -39.974 -6.548  1.00 36.67  ? 245 MET   L C   1 
ATOM   6377 O  O   . MET   C 1 259 ? 8.018   -40.123 -7.431  1.00 37.00  ? 245 MET   L O   1 
ATOM   6378 C  CB  . MET   C 1 259 ? 4.980   -41.192 -6.722  1.00 37.05  ? 245 MET   L CB  1 
ATOM   6379 C  CG  . MET   C 1 259 ? 4.111   -42.385 -6.374  1.00 38.81  ? 245 MET   L CG  1 
ATOM   6380 S  SD  . MET   C 1 259 ? 4.854   -43.960 -6.862  1.00 42.97  ? 245 MET   L SD  1 
ATOM   6381 C  CE  . MET   C 1 259 ? 4.681   -43.808 -8.641  1.00 51.02  ? 245 MET   L CE  1 
ATOM   6382 N  N   . ASN   C 1 260 ? 6.874   -38.768 -6.031  1.00 34.03  ? 246 ASN   L N   1 
ATOM   6383 C  CA  . ASN   C 1 260 ? 7.619   -37.537 -6.392  1.00 35.34  ? 246 ASN   L CA  1 
ATOM   6384 C  C   . ASN   C 1 260 ? 9.115   -37.712 -6.062  1.00 34.72  ? 246 ASN   L C   1 
ATOM   6385 O  O   . ASN   C 1 260 ? 9.932   -37.240 -6.844  1.00 33.61  ? 246 ASN   L O   1 
ATOM   6386 C  CB  . ASN   C 1 260 ? 7.119   -36.249 -5.728  1.00 38.94  ? 246 ASN   L CB  1 
ATOM   6387 C  CG  . ASN   C 1 260 ? 5.687   -35.925 -6.107  1.00 47.19  ? 246 ASN   L CG  1 
ATOM   6388 O  OD1 . ASN   C 1 260 ? 5.215   -36.332 -7.158  1.00 41.32  ? 246 ASN   L OD1 1 
ATOM   6389 N  ND2 . ASN   C 1 260 ? 4.981   -35.253 -5.226  1.00 48.98  ? 246 ASN   L ND2 1 
ATOM   6390 N  N   . THR   C 1 261 ? 9.443   -38.326 -4.929  1.00 33.28  ? 247 THR   L N   1 
ATOM   6391 C  CA  . THR   C 1 261 ? 10.851  -38.481 -4.485  1.00 34.40  ? 247 THR   L CA  1 
ATOM   6392 C  C   . THR   C 1 261 ? 11.564  -39.387 -5.502  1.00 33.71  ? 247 THR   L C   1 
ATOM   6393 O  O   . THR   C 1 261 ? 12.721  -39.040 -5.902  1.00 32.30  ? 247 THR   L O   1 
ATOM   6394 C  CB  . THR   C 1 261 ? 10.959  -38.956 -3.027  1.00 33.90  ? 247 THR   L CB  1 
ATOM   6395 O  OG1 . THR   C 1 261 ? 10.478  -37.935 -2.150  1.00 31.99  ? 247 THR   L OG1 1 
ATOM   6396 C  CG2 . THR   C 1 261 ? 12.379  -39.310 -2.624  1.00 34.31  ? 247 THR   L CG2 1 
ATOM   6397 N  N   . VAL   C 1 262 ? 10.948  -40.498 -5.915  1.00 29.93  ? 248 VAL   L N   1 
ATOM   6398 C  CA  . VAL   C 1 262 ? 11.667  -41.415 -6.853  1.00 33.17  ? 248 VAL   L CA  1 
ATOM   6399 C  C   . VAL   C 1 262 ? 12.007  -40.669 -8.139  1.00 35.03  ? 248 VAL   L C   1 
ATOM   6400 O  O   . VAL   C 1 262 ? 13.164  -40.767 -8.561  1.00 30.44  ? 248 VAL   L O   1 
ATOM   6401 C  CB  . VAL   C 1 262 ? 10.916  -42.729 -7.107  1.00 32.62  ? 248 VAL   L CB  1 
ATOM   6402 C  CG1 . VAL   C 1 262 ? 11.701  -43.630 -8.051  1.00 35.29  ? 248 VAL   L CG1 1 
ATOM   6403 C  CG2 . VAL   C 1 262 ? 10.648  -43.469 -5.805  1.00 32.28  ? 248 VAL   L CG2 1 
ATOM   6404 N  N   . GLU   C 1 263 ? 11.079  -39.862 -8.684  1.00 35.18  ? 249 GLU   L N   1 
ATOM   6405 C  CA  . GLU   C 1 263 ? 11.290  -39.149 -9.970  1.00 38.23  ? 249 GLU   L CA  1 
ATOM   6406 C  C   . GLU   C 1 263 ? 12.283  -38.016 -9.759  1.00 33.90  ? 249 GLU   L C   1 
ATOM   6407 O  O   . GLU   C 1 263 ? 13.051  -37.697 -10.656 1.00 36.14  ? 249 GLU   L O   1 
ATOM   6408 C  CB  . GLU   C 1 263 ? 9.954   -38.657 -10.550 1.00 43.87  ? 249 GLU   L CB  1 
ATOM   6409 C  CG  . GLU   C 1 263 ? 9.090   -39.782 -11.128 1.00 48.31  ? 249 GLU   L CG  1 
ATOM   6410 C  CD  . GLU   C 1 263 ? 9.820   -40.698 -12.121 1.00 53.60  ? 249 GLU   L CD  1 
ATOM   6411 O  OE1 . GLU   C 1 263 ? 10.753  -40.215 -12.842 1.00 49.06  ? 249 GLU   L OE1 1 
ATOM   6412 O  OE2 . GLU   C 1 263 ? 9.470   -41.894 -12.169 1.00 52.30  ? 249 GLU   L OE2 1 
ATOM   6413 N  N   . ARG   C 1 264 ? 12.304  -37.423 -8.576  1.00 34.34  ? 250 ARG   L N   1 
ATOM   6414 C  CA  . ARG   C 1 264 ? 13.287  -36.364 -8.293  1.00 33.50  ? 250 ARG   L CA  1 
ATOM   6415 C  C   . ARG   C 1 264 ? 14.691  -36.972 -8.315  1.00 33.33  ? 250 ARG   L C   1 
ATOM   6416 O  O   . ARG   C 1 264 ? 15.609  -36.340 -8.847  1.00 33.82  ? 250 ARG   L O   1 
ATOM   6417 C  CB  . ARG   C 1 264 ? 13.014  -35.753 -6.927  1.00 36.35  ? 250 ARG   L CB  1 
ATOM   6418 C  CG  . ARG   C 1 264 ? 14.050  -34.726 -6.498  1.00 36.94  ? 250 ARG   L CG  1 
ATOM   6419 C  CD  . ARG   C 1 264 ? 13.718  -34.208 -5.121  1.00 40.97  ? 250 ARG   L CD  1 
ATOM   6420 N  NE  . ARG   C 1 264 ? 14.802  -33.389 -4.645  1.00 40.78  ? 250 ARG   L NE  1 
ATOM   6421 C  CZ  . ARG   C 1 264 ? 14.940  -32.963 -3.410  1.00 43.00  ? 250 ARG   L CZ  1 
ATOM   6422 N  NH1 . ARG   C 1 264 ? 14.019  -33.245 -2.501  1.00 40.95  ? 250 ARG   L NH1 1 
ATOM   6423 N  NH2 . ARG   C 1 264 ? 15.992  -32.241 -3.110  1.00 43.90  ? 250 ARG   L NH2 1 
ATOM   6424 N  N   . ILE   C 1 265 ? 14.859  -38.103 -7.653  1.00 32.44  ? 251 ILE   L N   1 
ATOM   6425 C  CA  . ILE   C 1 265 ? 16.156  -38.828 -7.603  1.00 31.29  ? 251 ILE   L CA  1 
ATOM   6426 C  C   . ILE   C 1 265 ? 16.563  -39.211 -9.041  1.00 32.22  ? 251 ILE   L C   1 
ATOM   6427 O  O   . ILE   C 1 265 ? 17.754  -38.973 -9.396  1.00 33.17  ? 251 ILE   L O   1 
ATOM   6428 C  CB  . ILE   C 1 265 ? 16.105  -40.053 -6.677  1.00 31.99  ? 251 ILE   L CB  1 
ATOM   6429 C  CG1 . ILE   C 1 265 ? 16.011  -39.636 -5.201  1.00 33.70  ? 251 ILE   L CG1 1 
ATOM   6430 C  CG2 . ILE   C 1 265 ? 17.297  -40.968 -6.932  1.00 35.70  ? 251 ILE   L CG2 1 
ATOM   6431 C  CD1 . ILE   C 1 265 ? 15.537  -40.704 -4.289  1.00 33.17  ? 251 ILE   L CD1 1 
ATOM   6432 N  N   . ARG   C 1 266 ? 15.648  -39.775 -9.828  1.00 36.25  ? 252 ARG   L N   1 
ATOM   6433 C  CA  . ARG   C 1 266 ? 15.911  -40.108 -11.263 1.00 36.12  ? 252 ARG   L CA  1 
ATOM   6434 C  C   . ARG   C 1 266 ? 16.436  -38.882 -12.028 1.00 40.24  ? 252 ARG   L C   1 
ATOM   6435 O  O   . ARG   C 1 266 ? 17.435  -39.037 -12.771 1.00 35.98  ? 252 ARG   L O   1 
ATOM   6436 C  CB  . ARG   C 1 266 ? 14.666  -40.687 -11.922 1.00 37.81  ? 252 ARG   L CB  1 
ATOM   6437 C  CG  . ARG   C 1 266 ? 14.995  -41.394 -13.231 1.00 44.35  ? 252 ARG   L CG  1 
ATOM   6438 C  CD  . ARG   C 1 266 ? 13.781  -41.819 -14.040 1.00 41.11  ? 252 ARG   L CD  1 
ATOM   6439 N  NE  . ARG   C 1 266 ? 12.707  -42.366 -13.218 1.00 40.36  ? 252 ARG   L NE  1 
ATOM   6440 C  CZ  . ARG   C 1 266 ? 12.690  -43.585 -12.680 1.00 39.18  ? 252 ARG   L CZ  1 
ATOM   6441 N  NH1 . ARG   C 1 266 ? 13.714  -44.414 -12.844 1.00 37.61  ? 252 ARG   L NH1 1 
ATOM   6442 N  NH2 . ARG   C 1 266 ? 11.625  -43.978 -12.003 1.00 40.74  ? 252 ARG   L NH2 1 
ATOM   6443 N  N   . ARG   C 1 267 ? 15.842  -37.702 -11.828 1.00 36.51  ? 253 ARG   L N   1 
ATOM   6444 C  CA  . ARG   C 1 267 ? 16.221  -36.461 -12.553 1.00 38.43  ? 253 ARG   L CA  1 
ATOM   6445 C  C   . ARG   C 1 267 ? 17.596  -35.964 -12.047 1.00 41.38  ? 253 ARG   L C   1 
ATOM   6446 O  O   . ARG   C 1 267 ? 18.467  -35.563 -12.854 1.00 35.61  ? 253 ARG   L O   1 
ATOM   6447 C  CB  . ARG   C 1 267 ? 15.114  -35.401 -12.444 1.00 42.22  ? 253 ARG   L CB  1 
ATOM   6448 C  CG  . ARG   C 1 267 ? 15.611  -33.986 -12.721 1.00 54.53  ? 253 ARG   L CG  1 
ATOM   6449 C  CD  . ARG   C 1 267 ? 14.819  -32.826 -12.144 1.00 66.10  ? 253 ARG   L CD  1 
ATOM   6450 N  NE  . ARG   C 1 267 ? 14.662  -32.702 -10.678 1.00 73.05  ? 253 ARG   L NE  1 
ATOM   6451 C  CZ  . ARG   C 1 267 ? 15.531  -32.144 -9.822  1.00 65.57  ? 253 ARG   L CZ  1 
ATOM   6452 N  NH1 . ARG   C 1 267 ? 16.716  -31.721 -10.229 1.00 63.35  ? 253 ARG   L NH1 1 
ATOM   6453 N  NH2 . ARG   C 1 267 ? 15.220  -32.050 -8.540  1.00 66.53  ? 253 ARG   L NH2 1 
ATOM   6454 N  N   . ILE   C 1 268 ? 17.819  -35.954 -10.743 1.00 36.13  ? 254 ILE   L N   1 
ATOM   6455 C  CA  . ILE   C 1 268 ? 19.143  -35.565 -10.182 1.00 39.65  ? 254 ILE   L CA  1 
ATOM   6456 C  C   . ILE   C 1 268 ? 20.218  -36.503 -10.738 1.00 35.63  ? 254 ILE   L C   1 
ATOM   6457 O  O   . ILE   C 1 268 ? 21.265  -35.984 -11.118 1.00 36.57  ? 254 ILE   L O   1 
ATOM   6458 C  CB  . ILE   C 1 268 ? 19.171  -35.585 -8.642  1.00 40.16  ? 254 ILE   L CB  1 
ATOM   6459 C  CG1 . ILE   C 1 268 ? 18.199  -34.560 -8.037  1.00 43.44  ? 254 ILE   L CG1 1 
ATOM   6460 C  CG2 . ILE   C 1 268 ? 20.595  -35.349 -8.147  1.00 41.77  ? 254 ILE   L CG2 1 
ATOM   6461 C  CD1 . ILE   C 1 268 ? 17.927  -34.783 -6.555  1.00 44.20  ? 254 ILE   L CD1 1 
ATOM   6462 N  N   . ALA   C 1 269 ? 19.979  -37.816 -10.800 1.00 35.93  ? 255 ALA   L N   1 
ATOM   6463 C  CA  . ALA   C 1 269 ? 20.974  -38.782 -11.299 1.00 36.03  ? 255 ALA   L CA  1 
ATOM   6464 C  C   . ALA   C 1 269 ? 21.309  -38.458 -12.771 1.00 37.34  ? 255 ALA   L C   1 
ATOM   6465 O  O   . ALA   C 1 269 ? 22.505  -38.510 -13.131 1.00 33.95  ? 255 ALA   L O   1 
ATOM   6466 C  CB  . ALA   C 1 269 ? 20.454  -40.177 -11.151 1.00 35.28  ? 255 ALA   L CB  1 
ATOM   6467 N  N   . GLN   C 1 270 ? 20.293  -38.167 -13.585 1.00 41.07  ? 256 GLN   L N   1 
ATOM   6468 C  CA  . GLN   C 1 270 ? 20.407  -37.761 -15.022 1.00 40.28  ? 256 GLN   L CA  1 
ATOM   6469 C  C   . GLN   C 1 270 ? 21.193  -36.450 -15.153 1.00 37.92  ? 256 GLN   L C   1 
ATOM   6470 O  O   . GLN   C 1 270 ? 22.187  -36.410 -15.872 1.00 40.53  ? 256 GLN   L O   1 
ATOM   6471 C  CB  . GLN   C 1 270 ? 19.026  -37.692 -15.670 1.00 48.07  ? 256 GLN   L CB  1 
ATOM   6472 C  CG  . GLN   C 1 270 ? 19.059  -37.414 -17.182 1.00 52.90  ? 256 GLN   L CG  1 
ATOM   6473 C  CD  . GLN   C 1 270 ? 18.140  -36.283 -17.600 1.00 66.72  ? 256 GLN   L CD  1 
ATOM   6474 O  OE1 . GLN   C 1 270 ? 17.139  -35.976 -16.944 1.00 60.62  ? 256 GLN   L OE1 1 
ATOM   6475 N  NE2 . GLN   C 1 270 ? 18.481  -35.633 -18.702 1.00 61.96  ? 256 GLN   L NE2 1 
ATOM   6476 N  N   . GLU   C 1 271 ? 20.835  -35.410 -14.435 1.00 38.14  ? 257 GLU   L N   1 
ATOM   6477 C  CA  . GLU   C 1 271 ? 21.419  -34.060 -14.604 1.00 41.95  ? 257 GLU   L CA  1 
ATOM   6478 C  C   . GLU   C 1 271 ? 22.861  -34.026 -14.059 1.00 48.86  ? 257 GLU   L C   1 
ATOM   6479 O  O   . GLU   C 1 271 ? 23.642  -33.240 -14.574 1.00 47.56  ? 257 GLU   L O   1 
ATOM   6480 C  CB  . GLU   C 1 271 ? 20.513  -33.020 -13.927 1.00 45.13  ? 257 GLU   L CB  1 
ATOM   6481 C  CG  . GLU   C 1 271 ? 19.184  -32.789 -14.669 1.00 46.86  ? 257 GLU   L CG  1 
ATOM   6482 C  CD  . GLU   C 1 271 ? 18.181  -31.863 -13.983 1.00 52.45  ? 257 GLU   L CD  1 
ATOM   6483 O  OE1 . GLU   C 1 271 ? 18.523  -31.254 -12.928 1.00 54.40  ? 257 GLU   L OE1 1 
ATOM   6484 O  OE2 . GLU   C 1 271 ? 17.038  -31.793 -14.464 1.00 59.22  ? 257 GLU   L OE2 1 
ATOM   6485 N  N   . THR   C 1 272 ? 23.233  -34.829 -13.053 1.00 44.54  ? 258 THR   L N   1 
ATOM   6486 C  CA  . THR   C 1 272 ? 24.587  -34.782 -12.446 1.00 42.28  ? 258 THR   L CA  1 
ATOM   6487 C  C   . THR   C 1 272 ? 25.408  -36.026 -12.841 1.00 45.54  ? 258 THR   L C   1 
ATOM   6488 O  O   . THR   C 1 272 ? 26.529  -36.146 -12.378 1.00 41.53  ? 258 THR   L O   1 
ATOM   6489 C  CB  . THR   C 1 272 ? 24.465  -34.622 -10.923 1.00 45.33  ? 258 THR   L CB  1 
ATOM   6490 O  OG1 . THR   C 1 272 ? 23.950  -35.873 -10.450 1.00 37.45  ? 258 THR   L OG1 1 
ATOM   6491 C  CG2 . THR   C 1 272 ? 23.576  -33.461 -10.505 1.00 43.52  ? 258 THR   L CG2 1 
ATOM   6492 N  N   . LYS   C 1 273 ? 24.872  -36.928 -13.664 1.00 39.22  ? 259 LYS   L N   1 
ATOM   6493 C  CA  . LYS   C 1 273 ? 25.523  -38.215 -14.048 1.00 41.31  ? 259 LYS   L CA  1 
ATOM   6494 C  C   . LYS   C 1 273 ? 25.967  -38.973 -12.789 1.00 40.62  ? 259 LYS   L C   1 
ATOM   6495 O  O   . LYS   C 1 273 ? 27.118  -39.427 -12.722 1.00 43.78  ? 259 LYS   L O   1 
ATOM   6496 C  CB  . LYS   C 1 273 ? 26.682  -37.977 -15.019 1.00 51.92  ? 259 LYS   L CB  1 
ATOM   6497 C  CG  . LYS   C 1 273 ? 26.432  -36.891 -16.073 1.00 66.92  ? 259 LYS   L CG  1 
ATOM   6498 C  CD  . LYS   C 1 273 ? 27.722  -36.263 -16.608 1.00 80.82  ? 259 LYS   L CD  1 
ATOM   6499 C  CE  . LYS   C 1 273 ? 27.591  -34.833 -17.112 1.00 92.49  ? 259 LYS   L CE  1 
ATOM   6500 N  NZ  . LYS   C 1 273 ? 26.911  -34.766 -18.429 1.00 101.65 ? 259 LYS   L NZ  1 
ATOM   6501 N  N   . SER   C 1 274 ? 25.059  -39.207 -11.853 1.00 36.89  ? 260 SER   L N   1 
ATOM   6502 C  CA  . SER   C 1 274 ? 25.359  -39.875 -10.562 1.00 37.53  ? 260 SER   L CA  1 
ATOM   6503 C  C   . SER   C 1 274 ? 24.818  -41.301 -10.590 1.00 36.57  ? 260 SER   L C   1 
ATOM   6504 O  O   . SER   C 1 274 ? 23.734  -41.508 -11.102 1.00 36.00  ? 260 SER   L O   1 
ATOM   6505 C  CB  . SER   C 1 274 ? 24.837  -39.112 -9.368  1.00 37.43  ? 260 SER   L CB  1 
ATOM   6506 O  OG  . SER   C 1 274 ? 25.406  -37.805 -9.299  1.00 38.34  ? 260 SER   L OG  1 
ATOM   6507 N  N   . GLN   C 1 275 ? 25.493  -42.218 -9.908  1.00 37.08  ? 261 GLN   L N   1 
ATOM   6508 C  CA  . GLN   C 1 275 ? 24.929  -43.552 -9.587  1.00 38.09  ? 261 GLN   L CA  1 
ATOM   6509 C  C   . GLN   C 1 275 ? 23.885  -43.387 -8.473  1.00 38.13  ? 261 GLN   L C   1 
ATOM   6510 O  O   . GLN   C 1 275 ? 24.000  -42.430 -7.637  1.00 39.04  ? 261 GLN   L O   1 
ATOM   6511 C  CB  . GLN   C 1 275 ? 25.992  -44.506 -9.049  1.00 38.51  ? 261 GLN   L CB  1 
ATOM   6512 C  CG  . GLN   C 1 275 ? 27.151  -44.785 -9.975  1.00 44.36  ? 261 GLN   L CG  1 
ATOM   6513 C  CD  . GLN   C 1 275 ? 28.186  -45.571 -9.198  1.00 46.19  ? 261 GLN   L CD  1 
ATOM   6514 O  OE1 . GLN   C 1 275 ? 27.890  -46.623 -8.640  1.00 41.73  ? 261 GLN   L OE1 1 
ATOM   6515 N  NE2 . GLN   C 1 275 ? 29.400  -45.065 -9.141  1.00 46.25  ? 261 GLN   L NE2 1 
ATOM   6516 N  N   . VAL   C 1 276 ? 22.892  -44.257 -8.459  1.00 35.03  ? 262 VAL   L N   1 
ATOM   6517 C  CA  . VAL   C 1 276 ? 21.884  -44.301 -7.383  1.00 37.43  ? 262 VAL   L CA  1 
ATOM   6518 C  C   . VAL   C 1 276 ? 22.107  -45.596 -6.597  1.00 38.14  ? 262 VAL   L C   1 
ATOM   6519 O  O   . VAL   C 1 276 ? 21.912  -46.664 -7.148  1.00 35.77  ? 262 VAL   L O   1 
ATOM   6520 C  CB  . VAL   C 1 276 ? 20.462  -44.179 -7.942  1.00 40.64  ? 262 VAL   L CB  1 
ATOM   6521 C  CG1 . VAL   C 1 276 ? 19.452  -44.281 -6.812  1.00 38.05  ? 262 VAL   L CG1 1 
ATOM   6522 C  CG2 . VAL   C 1 276 ? 20.270  -42.883 -8.760  1.00 38.74  ? 262 VAL   L CG2 1 
ATOM   6523 N  N   . TRP   C 1 277 ? 22.425  -45.464 -5.321  1.00 35.63  ? 263 TRP   L N   1 
ATOM   6524 C  CA  . TRP   C 1 277 ? 22.603  -46.607 -4.396  1.00 34.69  ? 263 TRP   L CA  1 
ATOM   6525 C  C   . TRP   C 1 277 ? 21.296  -46.786 -3.594  1.00 35.03  ? 263 TRP   L C   1 
ATOM   6526 O  O   . TRP   C 1 277 ? 20.913  -45.903 -2.805  1.00 35.89  ? 263 TRP   L O   1 
ATOM   6527 C  CB  . TRP   C 1 277 ? 23.813  -46.398 -3.519  1.00 34.51  ? 263 TRP   L CB  1 
ATOM   6528 C  CG  . TRP   C 1 277 ? 25.119  -46.484 -4.240  1.00 40.96  ? 263 TRP   L CG  1 
ATOM   6529 C  CD1 . TRP   C 1 277 ? 25.317  -46.504 -5.583  1.00 42.96  ? 263 TRP   L CD1 1 
ATOM   6530 C  CD2 . TRP   C 1 277 ? 26.431  -46.514 -3.649  1.00 36.00  ? 263 TRP   L CD2 1 
ATOM   6531 N  NE1 . TRP   C 1 277 ? 26.655  -46.583 -5.862  1.00 41.75  ? 263 TRP   L NE1 1 
ATOM   6532 C  CE2 . TRP   C 1 277 ? 27.358  -46.566 -4.698  1.00 37.67  ? 263 TRP   L CE2 1 
ATOM   6533 C  CE3 . TRP   C 1 277 ? 26.905  -46.538 -2.342  1.00 39.42  ? 263 TRP   L CE3 1 
ATOM   6534 C  CZ2 . TRP   C 1 277 ? 28.733  -46.650 -4.486  1.00 42.17  ? 263 TRP   L CZ2 1 
ATOM   6535 C  CZ3 . TRP   C 1 277 ? 28.259  -46.637 -2.124  1.00 39.40  ? 263 TRP   L CZ3 1 
ATOM   6536 C  CH2 . TRP   C 1 277 ? 29.160  -46.688 -3.178  1.00 40.97  ? 263 TRP   L CH2 1 
ATOM   6537 N  N   . PHE   C 1 278 ? 20.667  -47.925 -3.810  1.00 33.05  ? 264 PHE   L N   1 
ATOM   6538 C  CA  . PHE   C 1 278 ? 19.333  -48.272 -3.272  1.00 33.93  ? 264 PHE   L CA  1 
ATOM   6539 C  C   . PHE   C 1 278 ? 19.503  -48.664 -1.814  1.00 34.82  ? 264 PHE   L C   1 
ATOM   6540 O  O   . PHE   C 1 278 ? 20.630  -49.043 -1.380  1.00 37.01  ? 264 PHE   L O   1 
ATOM   6541 C  CB  . PHE   C 1 278 ? 18.683  -49.344 -4.152  1.00 34.25  ? 264 PHE   L CB  1 
ATOM   6542 C  CG  . PHE   C 1 278 ? 18.583  -48.983 -5.620  1.00 35.72  ? 264 PHE   L CG  1 
ATOM   6543 C  CD1 . PHE   C 1 278 ? 17.991  -47.791 -6.031  1.00 33.70  ? 264 PHE   L CD1 1 
ATOM   6544 C  CD2 . PHE   C 1 278 ? 19.089  -49.819 -6.600  1.00 38.04  ? 264 PHE   L CD2 1 
ATOM   6545 C  CE1 . PHE   C 1 278 ? 17.858  -47.472 -7.382  1.00 37.19  ? 264 PHE   L CE1 1 
ATOM   6546 C  CE2 . PHE   C 1 278 ? 19.013  -49.471 -7.952  1.00 40.64  ? 264 PHE   L CE2 1 
ATOM   6547 C  CZ  . PHE   C 1 278 ? 18.370  -48.305 -8.344  1.00 36.96  ? 264 PHE   L CZ  1 
ATOM   6548 N  N   . GLY   C 1 279 ? 18.409  -48.616 -1.073  1.00 34.02  ? 265 GLY   L N   1 
ATOM   6549 C  CA  . GLY   C 1 279 ? 18.429  -49.032 0.344   1.00 34.43  ? 265 GLY   L CA  1 
ATOM   6550 C  C   . GLY   C 1 279 ? 18.803  -50.503 0.536   1.00 39.67  ? 265 GLY   L C   1 
ATOM   6551 O  O   . GLY   C 1 279 ? 19.556  -50.786 1.445   1.00 36.69  ? 265 GLY   L O   1 
ATOM   6552 N  N   . HIS   C 1 280 ? 18.231  -51.440 -0.224  1.00 35.10  ? 266 HIS   L N   1 
ATOM   6553 C  CA  . HIS   C 1 280 ? 18.233  -52.878 0.171   1.00 34.98  ? 266 HIS   L CA  1 
ATOM   6554 C  C   . HIS   C 1 280 ? 18.213  -53.790 -1.068  1.00 34.07  ? 266 HIS   L C   1 
ATOM   6555 O  O   . HIS   C 1 280 ? 17.341  -54.648 -1.178  1.00 39.22  ? 266 HIS   L O   1 
ATOM   6556 C  CB  . HIS   C 1 280 ? 17.033  -53.166 1.063   1.00 33.77  ? 266 HIS   L CB  1 
ATOM   6557 C  CG  . HIS   C 1 280 ? 17.001  -52.460 2.371   1.00 39.83  ? 266 HIS   L CG  1 
ATOM   6558 N  ND1 . HIS   C 1 280 ? 18.006  -52.571 3.314   1.00 33.70  ? 266 HIS   L ND1 1 
ATOM   6559 C  CD2 . HIS   C 1 280 ? 16.076  -51.614 2.885   1.00 37.40  ? 266 HIS   L CD2 1 
ATOM   6560 C  CE1 . HIS   C 1 280 ? 17.650  -51.860 4.374   1.00 37.12  ? 266 HIS   L CE1 1 
ATOM   6561 N  NE2 . HIS   C 1 280 ? 16.476  -51.276 4.124   1.00 35.01  ? 266 HIS   L NE2 1 
ATOM   6562 N  N   . ASP   C 1 281 ? 19.066  -53.514 -2.037  1.00 35.54  ? 267 ASP   L N   1 
ATOM   6563 C  CA  . ASP   C 1 281 ? 19.079  -54.245 -3.324  1.00 35.95  ? 267 ASP   L CA  1 
ATOM   6564 C  C   . ASP   C 1 281 ? 20.177  -55.322 -3.247  1.00 37.96  ? 267 ASP   L C   1 
ATOM   6565 O  O   . ASP   C 1 281 ? 21.351  -54.971 -3.374  1.00 39.12  ? 267 ASP   L O   1 
ATOM   6566 C  CB  . ASP   C 1 281 ? 19.287  -53.300 -4.500  1.00 40.11  ? 267 ASP   L CB  1 
ATOM   6567 C  CG  . ASP   C 1 281 ? 19.094  -53.968 -5.865  1.00 40.06  ? 267 ASP   L CG  1 
ATOM   6568 O  OD1 . ASP   C 1 281 ? 19.542  -55.126 -6.042  1.00 44.34  ? 267 ASP   L OD1 1 
ATOM   6569 O  OD2 . ASP   C 1 281 ? 18.460  -53.331 -6.705  1.00 46.23  ? 267 ASP   L OD2 1 
ATOM   6570 N  N   . ALA   C 1 282 ? 19.793  -56.579 -3.029  1.00 39.21  ? 268 ALA   L N   1 
ATOM   6571 C  CA  . ALA   C 1 282 ? 20.748  -57.718 -2.888  1.00 43.23  ? 268 ALA   L CA  1 
ATOM   6572 C  C   . ALA   C 1 282 ? 21.722  -57.746 -4.087  1.00 40.64  ? 268 ALA   L C   1 
ATOM   6573 O  O   . ALA   C 1 282 ? 22.927  -57.919 -3.842  1.00 41.72  ? 268 ALA   L O   1 
ATOM   6574 C  CB  . ALA   C 1 282 ? 20.016  -59.056 -2.728  1.00 38.67  ? 268 ALA   L CB  1 
ATOM   6575 N  N   . GLU   C 1 283 ? 21.243  -57.586 -5.319  1.00 39.23  ? 269 GLU   L N   1 
ATOM   6576 C  CA  . GLU   C 1 283 ? 22.117  -57.722 -6.522  1.00 47.90  ? 269 GLU   L CA  1 
ATOM   6577 C  C   . GLU   C 1 283 ? 23.052  -56.510 -6.627  1.00 49.28  ? 269 GLU   L C   1 
ATOM   6578 O  O   . GLU   C 1 283 ? 24.250  -56.718 -6.847  1.00 41.97  ? 269 GLU   L O   1 
ATOM   6579 C  CB  . GLU   C 1 283 ? 21.299  -57.952 -7.792  1.00 55.07  ? 269 GLU   L CB  1 
ATOM   6580 C  CG  . GLU   C 1 283 ? 20.431  -59.196 -7.700  1.00 72.25  ? 269 GLU   L CG  1 
ATOM   6581 C  CD  . GLU   C 1 283 ? 19.736  -59.601 -8.992  1.00 97.12  ? 269 GLU   L CD  1 
ATOM   6582 O  OE1 . GLU   C 1 283 ? 19.921  -58.900 -10.021 1.00 113.39 ? 269 GLU   L OE1 1 
ATOM   6583 O  OE2 . GLU   C 1 283 ? 19.017  -60.628 -8.971  1.00 111.79 ? 269 GLU   L OE2 1 
ATOM   6584 N  N   . GLN   C 1 284 ? 22.568  -55.275 -6.436  1.00 41.77  ? 270 GLN   L N   1 
ATOM   6585 C  CA  . GLN   C 1 284 ? 23.472  -54.103 -6.418  1.00 41.40  ? 270 GLN   L CA  1 
ATOM   6586 C  C   . GLN   C 1 284 ? 24.541  -54.254 -5.315  1.00 37.11  ? 270 GLN   L C   1 
ATOM   6587 O  O   . GLN   C 1 284 ? 25.721  -53.883 -5.527  1.00 39.41  ? 270 GLN   L O   1 
ATOM   6588 C  CB  . GLN   C 1 284 ? 22.670  -52.819 -6.216  1.00 40.21  ? 270 GLN   L CB  1 
ATOM   6589 C  CG  . GLN   C 1 284 ? 23.526  -51.568 -6.347  1.00 39.45  ? 270 GLN   L CG  1 
ATOM   6590 C  CD  . GLN   C 1 284 ? 22.712  -50.310 -6.110  1.00 43.42  ? 270 GLN   L CD  1 
ATOM   6591 O  OE1 . GLN   C 1 284 ? 22.106  -50.122 -5.049  1.00 39.16  ? 270 GLN   L OE1 1 
ATOM   6592 N  NE2 . GLN   C 1 284 ? 22.713  -49.424 -7.094  1.00 39.32  ? 270 GLN   L NE2 1 
ATOM   6593 N  N   . PHE   C 1 285 ? 24.143  -54.690 -4.130  1.00 34.07  ? 271 PHE   L N   1 
ATOM   6594 C  CA  . PHE   C 1 285 ? 25.021  -54.687 -2.941  1.00 38.47  ? 271 PHE   L CA  1 
ATOM   6595 C  C   . PHE   C 1 285 ? 26.171  -55.671 -3.201  1.00 42.79  ? 271 PHE   L C   1 
ATOM   6596 O  O   . PHE   C 1 285 ? 27.327  -55.388 -2.814  1.00 39.26  ? 271 PHE   L O   1 
ATOM   6597 C  CB  . PHE   C 1 285 ? 24.252  -55.133 -1.702  1.00 38.93  ? 271 PHE   L CB  1 
ATOM   6598 C  CG  . PHE   C 1 285 ? 25.057  -55.079 -0.446  1.00 40.23  ? 271 PHE   L CG  1 
ATOM   6599 C  CD1 . PHE   C 1 285 ? 25.375  -53.859 0.130   1.00 44.60  ? 271 PHE   L CD1 1 
ATOM   6600 C  CD2 . PHE   C 1 285 ? 25.526  -56.250 0.137   1.00 41.63  ? 271 PHE   L CD2 1 
ATOM   6601 C  CE1 . PHE   C 1 285 ? 26.151  -53.814 1.283   1.00 43.64  ? 271 PHE   L CE1 1 
ATOM   6602 C  CE2 . PHE   C 1 285 ? 26.270  -56.202 1.301   1.00 44.29  ? 271 PHE   L CE2 1 
ATOM   6603 C  CZ  . PHE   C 1 285 ? 26.578  -54.981 1.871   1.00 45.81  ? 271 PHE   L CZ  1 
ATOM   6604 N  N   . LYS   C 1 286 ? 25.844  -56.791 -3.845  1.00 44.75  ? 272 LYS   L N   1 
ATOM   6605 C  CA  . LYS   C 1 286 ? 26.832  -57.850 -4.191  1.00 52.66  ? 272 LYS   L CA  1 
ATOM   6606 C  C   . LYS   C 1 286 ? 27.995  -57.221 -4.962  1.00 49.93  ? 272 LYS   L C   1 
ATOM   6607 O  O   . LYS   C 1 286 ? 29.128  -57.623 -4.756  1.00 48.89  ? 272 LYS   L O   1 
ATOM   6608 C  CB  . LYS   C 1 286 ? 26.163  -58.876 -5.100  1.00 58.98  ? 272 LYS   L CB  1 
ATOM   6609 C  CG  . LYS   C 1 286 ? 26.413  -60.326 -4.757  1.00 71.90  ? 272 LYS   L CG  1 
ATOM   6610 C  CD  . LYS   C 1 286 ? 25.186  -61.166 -5.051  1.00 79.50  ? 272 LYS   L CD  1 
ATOM   6611 C  CE  . LYS   C 1 286 ? 25.393  -62.631 -4.750  1.00 89.53  ? 272 LYS   L CE  1 
ATOM   6612 N  NZ  . LYS   C 1 286 ? 24.594  -63.065 -3.581  1.00 94.47  ? 272 LYS   L NZ  1 
ATOM   6613 N  N   . LYS   C 1 287 ? 27.695  -56.262 -5.836  1.00 40.26  ? 273 LYS   L N   1 
ATOM   6614 C  CA  . LYS   C 1 287 ? 28.675  -55.670 -6.773  1.00 44.89  ? 273 LYS   L CA  1 
ATOM   6615 C  C   . LYS   C 1 287 ? 29.499  -54.585 -6.064  1.00 43.76  ? 273 LYS   L C   1 
ATOM   6616 O  O   . LYS   C 1 287 ? 30.556  -54.242 -6.605  1.00 44.54  ? 273 LYS   L O   1 
ATOM   6617 C  CB  . LYS   C 1 287 ? 27.964  -55.180 -8.039  1.00 51.62  ? 273 LYS   L CB  1 
ATOM   6618 C  CG  . LYS   C 1 287 ? 27.263  -56.298 -8.821  1.00 64.39  ? 273 LYS   L CG  1 
ATOM   6619 C  CD  . LYS   C 1 287 ? 26.262  -55.837 -9.873  1.00 73.44  ? 273 LYS   L CD  1 
ATOM   6620 C  CE  . LYS   C 1 287 ? 26.907  -55.458 -11.191 1.00 87.86  ? 273 LYS   L CE  1 
ATOM   6621 N  NZ  . LYS   C 1 287 ? 26.132  -54.416 -11.912 1.00 98.76  ? 273 LYS   L NZ  1 
ATOM   6622 N  N   . PHE   C 1 288 ? 29.084  -54.063 -4.899  1.00 36.18  ? 274 PHE   L N   1 
ATOM   6623 C  CA  . PHE   C 1 288 ? 29.837  -52.962 -4.239  1.00 36.86  ? 274 PHE   L CA  1 
ATOM   6624 C  C   . PHE   C 1 288 ? 31.160  -53.545 -3.739  1.00 36.78  ? 274 PHE   L C   1 
ATOM   6625 O  O   . PHE   C 1 288 ? 31.172  -54.725 -3.342  1.00 41.97  ? 274 PHE   L O   1 
ATOM   6626 C  CB  . PHE   C 1 288 ? 29.110  -52.375 -3.023  1.00 39.61  ? 274 PHE   L CB  1 
ATOM   6627 C  CG  . PHE   C 1 288 ? 27.867  -51.538 -3.282  1.00 38.39  ? 274 PHE   L CG  1 
ATOM   6628 C  CD1 . PHE   C 1 288 ? 27.729  -50.755 -4.421  1.00 41.23  ? 274 PHE   L CD1 1 
ATOM   6629 C  CD2 . PHE   C 1 288 ? 26.835  -51.537 -2.354  1.00 39.22  ? 274 PHE   L CD2 1 
ATOM   6630 C  CE1 . PHE   C 1 288 ? 26.571  -50.014 -4.643  1.00 43.54  ? 274 PHE   L CE1 1 
ATOM   6631 C  CE2 . PHE   C 1 288 ? 25.686  -50.778 -2.562  1.00 40.67  ? 274 PHE   L CE2 1 
ATOM   6632 C  CZ  . PHE   C 1 288 ? 25.552  -50.023 -3.712  1.00 41.34  ? 274 PHE   L CZ  1 
ATOM   6633 N  N   . ARG   C 1 289 ? 32.203  -52.730 -3.697  1.00 38.34  ? 275 ARG   L N   1 
ATOM   6634 C  CA  . ARG   C 1 289 ? 33.439  -53.022 -2.938  1.00 39.76  ? 275 ARG   L CA  1 
ATOM   6635 C  C   . ARG   C 1 289 ? 33.121  -52.691 -1.484  1.00 36.66  ? 275 ARG   L C   1 
ATOM   6636 O  O   . ARG   C 1 289 ? 32.829  -51.508 -1.177  1.00 41.02  ? 275 ARG   L O   1 
ATOM   6637 C  CB  . ARG   C 1 289 ? 34.565  -52.165 -3.536  1.00 50.10  ? 275 ARG   L CB  1 
ATOM   6638 C  CG  . ARG   C 1 289 ? 35.975  -52.444 -3.037  1.00 53.00  ? 275 ARG   L CG  1 
ATOM   6639 C  CD  . ARG   C 1 289 ? 36.987  -51.485 -3.657  1.00 55.29  ? 275 ARG   L CD  1 
ATOM   6640 N  NE  . ARG   C 1 289 ? 36.726  -51.307 -5.067  1.00 63.82  ? 275 ARG   L NE  1 
ATOM   6641 C  CZ  . ARG   C 1 289 ? 36.536  -50.161 -5.720  1.00 60.30  ? 275 ARG   L CZ  1 
ATOM   6642 N  NH1 . ARG   C 1 289 ? 36.596  -48.989 -5.133  1.00 62.12  ? 275 ARG   L NH1 1 
ATOM   6643 N  NH2 . ARG   C 1 289 ? 36.293  -50.195 -7.010  1.00 71.81  ? 275 ARG   L NH2 1 
ATOM   6644 N  N   . LYS   C 1 290 ? 33.190  -53.662 -0.602  1.00 34.75  ? 276 LYS   L N   1 
ATOM   6645 C  CA  . LYS   C 1 290 ? 32.887  -53.458 0.835   1.00 37.06  ? 276 LYS   L CA  1 
ATOM   6646 C  C   . LYS   C 1 290 ? 34.147  -53.124 1.612   1.00 39.87  ? 276 LYS   L C   1 
ATOM   6647 O  O   . LYS   C 1 290 ? 35.276  -53.295 1.071   1.00 37.18  ? 276 LYS   L O   1 
ATOM   6648 C  CB  . LYS   C 1 290 ? 32.243  -54.673 1.477   1.00 41.02  ? 276 LYS   L CB  1 
ATOM   6649 C  CG  . LYS   C 1 290 ? 31.455  -55.513 0.517   1.00 54.67  ? 276 LYS   L CG  1 
ATOM   6650 C  CD  . LYS   C 1 290 ? 30.146  -54.909 0.150   1.00 46.89  ? 276 LYS   L CD  1 
ATOM   6651 C  CE  . LYS   C 1 290 ? 29.301  -56.061 -0.360  1.00 54.64  ? 276 LYS   L CE  1 
ATOM   6652 N  NZ  . LYS   C 1 290 ? 29.846  -56.629 -1.617  1.00 49.94  ? 276 LYS   L NZ  1 
ATOM   6653 N  N   . SER   C 1 291 ? 33.956  -52.822 2.894   1.00 38.60  ? 277 SER   L N   1 
ATOM   6654 C  CA  . SER   C 1 291 ? 35.007  -52.247 3.764   1.00 37.02  ? 277 SER   L CA  1 
ATOM   6655 C  C   . SER   C 1 291 ? 36.108  -53.297 4.007   1.00 37.64  ? 277 SER   L C   1 
ATOM   6656 O  O   . SER   C 1 291 ? 37.174  -52.900 4.511   1.00 40.09  ? 277 SER   L O   1 
ATOM   6657 C  CB  . SER   C 1 291 ? 34.470  -51.722 5.054   1.00 32.67  ? 277 SER   L CB  1 
ATOM   6658 O  OG  . SER   C 1 291 ? 33.865  -52.761 5.822   1.00 35.15  ? 277 SER   L OG  1 
ATOM   6659 N  N   . THR   C 1 292 ? 35.868  -54.566 3.681   1.00 35.59  ? 278 THR   L N   1 
ATOM   6660 C  CA  . THR   C 1 292 ? 36.880  -55.656 3.859   1.00 44.15  ? 278 THR   L CA  1 
ATOM   6661 C  C   . THR   C 1 292 ? 37.828  -55.709 2.649   1.00 47.35  ? 278 THR   L C   1 
ATOM   6662 O  O   . THR   C 1 292 ? 38.874  -56.379 2.743   1.00 43.15  ? 278 THR   L O   1 
ATOM   6663 C  CB  . THR   C 1 292 ? 36.197  -57.007 4.091   1.00 40.87  ? 278 THR   L CB  1 
ATOM   6664 O  OG1 . THR   C 1 292 ? 35.109  -57.054 3.157   1.00 50.42  ? 278 THR   L OG1 1 
ATOM   6665 C  CG2 . THR   C 1 292 ? 35.702  -57.144 5.515   1.00 47.37  ? 278 THR   L CG2 1 
ATOM   6666 N  N   . GLU   C 1 293 ? 37.495  -55.028 1.553   1.00 41.72  ? 279 GLU   L N   1 
ATOM   6667 C  CA  . GLU   C 1 293 ? 38.306  -55.025 0.311   1.00 44.38  ? 279 GLU   L CA  1 
ATOM   6668 C  C   . GLU   C 1 293 ? 38.772  -53.622 -0.044  1.00 42.57  ? 279 GLU   L C   1 
ATOM   6669 O  O   . GLU   C 1 293 ? 39.764  -53.515 -0.770  1.00 37.66  ? 279 GLU   L O   1 
ATOM   6670 C  CB  . GLU   C 1 293 ? 37.504  -55.641 -0.830  1.00 48.98  ? 279 GLU   L CB  1 
ATOM   6671 C  CG  . GLU   C 1 293 ? 36.721  -56.870 -0.415  1.00 59.47  ? 279 GLU   L CG  1 
ATOM   6672 C  CD  . GLU   C 1 293 ? 35.559  -57.092 -1.371  1.00 80.90  ? 279 GLU   L CD  1 
ATOM   6673 O  OE1 . GLU   C 1 293 ? 35.831  -57.736 -2.408  1.00 79.99  ? 279 GLU   L OE1 1 
ATOM   6674 O  OE2 . GLU   C 1 293 ? 34.405  -56.543 -1.129  1.00 64.17  ? 279 GLU   L OE2 1 
ATOM   6675 N  N   . GLY   C 1 294 ? 38.069  -52.574 0.381   1.00 37.08  ? 280 GLY   L N   1 
ATOM   6676 C  CA  . GLY   C 1 294 ? 38.499  -51.206 0.062   1.00 36.16  ? 280 GLY   L CA  1 
ATOM   6677 C  C   . GLY   C 1 294 ? 37.386  -50.164 0.136   1.00 38.74  ? 280 GLY   L C   1 
ATOM   6678 O  O   . GLY   C 1 294 ? 36.546  -50.247 1.034   1.00 37.37  ? 280 GLY   L O   1 
ATOM   6679 N  N   . TYR   C 1 295 ? 37.419  -49.213 -0.787  1.00 35.29  ? 281 TYR   L N   1 
ATOM   6680 C  CA  . TYR   C 1 295 ? 36.751  -47.892 -0.667  1.00 37.55  ? 281 TYR   L CA  1 
ATOM   6681 C  C   . TYR   C 1 295 ? 36.661  -47.270 -2.058  1.00 39.69  ? 281 TYR   L C   1 
ATOM   6682 O  O   . TYR   C 1 295 ? 37.252  -47.809 -2.994  1.00 38.12  ? 281 TYR   L O   1 
ATOM   6683 C  CB  . TYR   C 1 295 ? 37.515  -46.950 0.272   1.00 36.38  ? 281 TYR   L CB  1 
ATOM   6684 C  CG  . TYR   C 1 295 ? 39.019  -47.016 0.132   1.00 36.03  ? 281 TYR   L CG  1 
ATOM   6685 C  CD1 . TYR   C 1 295 ? 39.676  -46.476 -0.965  1.00 39.94  ? 281 TYR   L CD1 1 
ATOM   6686 C  CD2 . TYR   C 1 295 ? 39.790  -47.668 1.089   1.00 43.30  ? 281 TYR   L CD2 1 
ATOM   6687 C  CE1 . TYR   C 1 295 ? 41.057  -46.572 -1.119  1.00 39.95  ? 281 TYR   L CE1 1 
ATOM   6688 C  CE2 . TYR   C 1 295 ? 41.178  -47.719 0.983   1.00 40.46  ? 281 TYR   L CE2 1 
ATOM   6689 C  CZ  . TYR   C 1 295 ? 41.817  -47.176 -0.129  1.00 42.40  ? 281 TYR   L CZ  1 
ATOM   6690 O  OH  . TYR   C 1 295 ? 43.190  -47.234 -0.241  1.00 46.32  ? 281 TYR   L OH  1 
ATOM   6691 N  N   . TYR   C 1 296 ? 35.939  -46.158 -2.153  1.00 37.74  ? 282 TYR   L N   1 
ATOM   6692 C  CA  . TYR   C 1 296 ? 35.707  -45.362 -3.371  1.00 40.28  ? 282 TYR   L CA  1 
ATOM   6693 C  C   . TYR   C 1 296 ? 36.394  -44.018 -3.126  1.00 38.28  ? 282 TYR   L C   1 
ATOM   6694 O  O   . TYR   C 1 296 ? 36.158  -43.423 -2.069  1.00 39.33  ? 282 TYR   L O   1 
ATOM   6695 C  CB  . TYR   C 1 296 ? 34.201  -45.227 -3.641  1.00 36.16  ? 282 TYR   L CB  1 
ATOM   6696 C  CG  . TYR   C 1 296 ? 33.502  -46.514 -4.000  1.00 36.94  ? 282 TYR   L CG  1 
ATOM   6697 C  CD1 . TYR   C 1 296 ? 33.076  -47.386 -3.016  1.00 40.34  ? 282 TYR   L CD1 1 
ATOM   6698 C  CD2 . TYR   C 1 296 ? 33.343  -46.916 -5.329  1.00 41.06  ? 282 TYR   L CD2 1 
ATOM   6699 C  CE1 . TYR   C 1 296 ? 32.495  -48.609 -3.323  1.00 35.18  ? 282 TYR   L CE1 1 
ATOM   6700 C  CE2 . TYR   C 1 296 ? 32.751  -48.129 -5.655  1.00 40.35  ? 282 TYR   L CE2 1 
ATOM   6701 C  CZ  . TYR   C 1 296 ? 32.297  -48.959 -4.644  1.00 39.41  ? 282 TYR   L CZ  1 
ATOM   6702 O  OH  . TYR   C 1 296 ? 31.753  -50.177 -4.926  1.00 39.03  ? 282 TYR   L OH  1 
ATOM   6703 N  N   . GLU   C 1 297 ? 37.293  -43.613 -4.010  1.00 38.14  ? 283 GLU   L N   1 
ATOM   6704 C  CA  . GLU   C 1 297 ? 37.685  -42.186 -4.120  1.00 44.08  ? 283 GLU   L CA  1 
ATOM   6705 C  C   . GLU   C 1 297 ? 37.098  -41.602 -5.441  1.00 36.01  ? 283 GLU   L C   1 
ATOM   6706 O  O   . GLU   C 1 297 ? 37.604  -40.399 -5.409  1.00 41.46  ? 283 GLU   L O   1 
ATOM   6707 C  CB  . GLU   C 1 297 ? 39.182  -41.982 -3.818  1.00 51.03  ? 283 GLU   L CB  1 
ATOM   6708 C  CG  . GLU   C 1 297 ? 40.177  -42.950 -4.388  1.00 63.98  ? 283 GLU   L CG  1 
ATOM   6709 C  CD  . GLU   C 1 297 ? 41.622  -42.774 -3.872  1.00 56.97  ? 283 GLU   L CD  1 
ATOM   6710 O  OE1 . GLU   C 1 297 ? 42.452  -42.353 -4.649  1.00 58.88  ? 283 GLU   L OE1 1 
ATOM   6711 O  OE2 . GLU   C 1 297 ? 41.918  -43.095 -2.712  1.00 50.65  ? 283 GLU   L OE2 1 
HETATM 6712 C  CAJ . A1AI3 D 2 .   ? 6.601   3.652   18.847  0.80 54.36  ? 301 A1AI3 X CAJ 1 
HETATM 6713 C  CAI . A1AI3 D 2 .   ? 7.312   2.309   18.828  0.80 56.23  ? 301 A1AI3 X CAI 1 
HETATM 6714 C  CAH . A1AI3 D 2 .   ? 8.444   2.352   17.819  0.80 51.39  ? 301 A1AI3 X CAH 1 
HETATM 6715 C  CAG . A1AI3 D 2 .   ? 8.369   1.124   16.929  0.80 51.42  ? 301 A1AI3 X CAG 1 
HETATM 6716 C  CAF . A1AI3 D 2 .   ? 9.444   0.138   17.328  0.80 54.50  ? 301 A1AI3 X CAF 1 
HETATM 6717 C  CAE . A1AI3 D 2 .   ? 10.249  -0.268  16.096  0.80 57.75  ? 301 A1AI3 X CAE 1 
HETATM 6718 C  CAD . A1AI3 D 2 .   ? 11.112  0.907   15.657  0.80 65.82  ? 301 A1AI3 X CAD 1 
HETATM 6719 C  CAC . A1AI3 D 2 .   ? 12.503  0.424   15.270  0.80 59.02  ? 301 A1AI3 X CAC 1 
HETATM 6720 O  OAO . A1AI3 D 2 .   ? 12.805  -0.750  15.445  0.80 65.09  ? 301 A1AI3 X OAO 1 
HETATM 6721 N  N   . A1AI3 D 2 .   ? 13.300  1.394   14.784  0.80 57.61  ? 301 A1AI3 X N   1 
HETATM 6722 C  CA  . A1AI3 D 2 .   ? 14.695  1.291   14.284  0.80 53.41  ? 301 A1AI3 X CA  1 
HETATM 6723 C  C   . A1AI3 D 2 .   ? 14.850  0.201   13.200  0.80 51.20  ? 301 A1AI3 X C   1 
HETATM 6724 O  OXT . A1AI3 D 2 .   ? 15.417  0.496   12.119  0.80 44.10  ? 301 A1AI3 X OXT 1 
HETATM 6725 O  O   . A1AI3 D 2 .   ? 14.479  -0.930  13.529  0.80 43.07  ? 301 A1AI3 X O   1 
HETATM 6726 C  CB  . A1AI3 D 2 .   ? 15.689  1.053   15.405  0.80 43.05  ? 301 A1AI3 X CB  1 
HETATM 6727 C  CAL . A1AI3 D 2 .   ? 17.090  1.109   14.817  0.80 45.58  ? 301 A1AI3 X CAL 1 
HETATM 6728 O  OAQ . A1AI3 D 2 .   ? 17.381  -0.075  14.079  0.80 42.37  ? 301 A1AI3 X OAQ 1 
HETATM 6729 CO CO  . CO    E 3 .   ? 14.551  -1.278  10.973  1.00 35.49  ? 302 CO    X CO  1 
HETATM 6730 S  S   . SO4   F 4 .   ? 19.119  -17.971 -1.774  1.00 95.60  ? 303 SO4   X S   1 
HETATM 6731 O  O1  . SO4   F 4 .   ? 18.000  -18.289 -2.661  1.00 71.62  ? 303 SO4   X O1  1 
HETATM 6732 O  O2  . SO4   F 4 .   ? 20.294  -18.757 -2.139  1.00 81.74  ? 303 SO4   X O2  1 
HETATM 6733 O  O3  . SO4   F 4 .   ? 19.460  -16.542 -1.889  1.00 74.96  ? 303 SO4   X O3  1 
HETATM 6734 O  O4  . SO4   F 4 .   ? 18.737  -18.310 -0.400  1.00 64.30  ? 303 SO4   X O4  1 
HETATM 6735 S  S   . SO4   G 4 .   ? 11.028  -13.283 -11.075 1.00 211.87 ? 304 SO4   X S   1 
HETATM 6736 O  O1  . SO4   G 4 .   ? 11.372  -14.585 -11.585 1.00 211.44 ? 304 SO4   X O1  1 
HETATM 6737 O  O2  . SO4   G 4 .   ? 10.450  -12.485 -12.130 1.00 154.05 ? 304 SO4   X O2  1 
HETATM 6738 O  O3  . SO4   G 4 .   ? 12.213  -12.630 -10.573 1.00 206.96 ? 304 SO4   X O3  1 
HETATM 6739 O  O4  . SO4   G 4 .   ? 10.077  -13.434 -10.004 1.00 222.18 ? 304 SO4   X O4  1 
HETATM 6740 FE FE  . FE    H 5 .   ? 18.000  0.103   11.716  1.00 36.99  ? 305 FE    X FE  1 
HETATM 6741 C  CAJ . A1AI3 I 2 .   ? 14.645  -18.871 29.867  0.70 56.27  ? 301 A1AI3 F CAJ 1 
HETATM 6742 C  CAI . A1AI3 I 2 .   ? 13.544  -18.246 29.033  0.70 55.79  ? 301 A1AI3 F CAI 1 
HETATM 6743 C  CAH . A1AI3 I 2 .   ? 12.203  -18.691 29.579  0.70 52.64  ? 301 A1AI3 F CAH 1 
HETATM 6744 C  CAG . A1AI3 I 2 .   ? 11.233  -18.868 28.426  0.70 52.38  ? 301 A1AI3 F CAG 1 
HETATM 6745 C  CAF . A1AI3 I 2 .   ? 10.299  -17.688 28.339  0.70 53.48  ? 301 A1AI3 F CAF 1 
HETATM 6746 C  CAE . A1AI3 I 2 .   ? 8.889   -18.208 28.114  0.70 53.14  ? 301 A1AI3 F CAE 1 
HETATM 6747 C  CAD . A1AI3 I 2 .   ? 8.331   -18.681 29.452  0.70 60.18  ? 301 A1AI3 F CAD 1 
HETATM 6748 C  CAC . A1AI3 I 2 .   ? 6.866   -18.290 29.560  0.70 53.16  ? 301 A1AI3 F CAC 1 
HETATM 6749 O  OAO . A1AI3 I 2 .   ? 6.412   -17.530 28.721  0.70 61.40  ? 301 A1AI3 F OAO 1 
HETATM 6750 N  N   . A1AI3 I 2 .   ? 6.229   -18.819 30.618  0.70 53.03  ? 301 A1AI3 F N   1 
HETATM 6751 C  CA  . A1AI3 I 2 .   ? 4.804   -18.688 31.033  0.70 51.81  ? 301 A1AI3 F CA  1 
HETATM 6752 C  C   . A1AI3 I 2 .   ? 3.786   -18.924 29.862  0.70 62.21  ? 301 A1AI3 F C   1 
HETATM 6753 O  OXT . A1AI3 I 2 .   ? 3.976   -18.240 28.860  0.70 57.33  ? 301 A1AI3 F OXT 1 
HETATM 6754 O  O   . A1AI3 I 2 .   ? 2.811   -19.709 30.022  0.70 43.24  ? 301 A1AI3 F O   1 
HETATM 6755 C  CB  . A1AI3 I 2 .   ? 4.542   -17.367 31.738  0.70 43.52  ? 301 A1AI3 F CB  1 
HETATM 6756 C  CAL . A1AI3 I 2 .   ? 3.130   -17.362 32.295  0.70 43.99  ? 301 A1AI3 F CAL 1 
HETATM 6757 O  OAQ . A1AI3 I 2 .   ? 2.176   -17.287 31.261  0.70 33.62  ? 301 A1AI3 F OAQ 1 
HETATM 6758 CO CO  . CO    J 3 .   ? 2.270   -20.140 28.084  1.00 32.96  ? 302 CO    F CO  1 
HETATM 6759 FE FE  . FE    K 5 .   ? 0.548   -19.079 31.192  1.00 37.58  ? 303 FE    F FE  1 
HETATM 6760 S  S   . SO4   L 4 .   ? -13.929 -20.358 13.795  1.00 94.25  ? 304 SO4   F S   1 
HETATM 6761 O  O1  . SO4   L 4 .   ? -13.660 -21.309 12.728  1.00 78.75  ? 304 SO4   F O1  1 
HETATM 6762 O  O2  . SO4   L 4 .   ? -12.987 -19.237 13.658  1.00 69.14  ? 304 SO4   F O2  1 
HETATM 6763 O  O3  . SO4   L 4 .   ? -13.775 -21.017 15.100  1.00 71.78  ? 304 SO4   F O3  1 
HETATM 6764 O  O4  . SO4   L 4 .   ? -15.301 -19.866 13.688  1.00 74.62  ? 304 SO4   F O4  1 
HETATM 6765 S  S   . SO4   M 4 .   ? -11.227 -32.616 10.361  1.00 191.49 ? 305 SO4   F S   1 
HETATM 6766 O  O1  . SO4   M 4 .   ? -12.058 -32.353 9.213   1.00 176.27 ? 305 SO4   F O1  1 
HETATM 6767 O  O2  . SO4   M 4 .   ? -9.955  -31.965 10.179  1.00 188.06 ? 305 SO4   F O2  1 
HETATM 6768 O  O3  . SO4   M 4 .   ? -11.038 -34.042 10.505  1.00 151.85 ? 305 SO4   F O3  1 
HETATM 6769 O  O4  . SO4   M 4 .   ? -11.856 -32.101 11.551  1.00 194.73 ? 305 SO4   F O4  1 
HETATM 6770 C  CAJ . A1AI3 N 2 .   ? 3.961   -53.694 12.459  0.75 55.90  ? 301 A1AI3 L CAJ 1 
HETATM 6771 C  CAI . A1AI3 N 2 .   ? 3.954   -53.233 11.016  0.75 56.25  ? 301 A1AI3 L CAI 1 
HETATM 6772 C  CAH . A1AI3 N 2 .   ? 4.982   -52.143 10.845  0.75 53.82  ? 301 A1AI3 L CAH 1 
HETATM 6773 C  CAG . A1AI3 N 2 .   ? 5.762   -52.387 9.577   0.75 55.51  ? 301 A1AI3 L CAG 1 
HETATM 6774 C  CAF . A1AI3 N 2 .   ? 5.625   -51.193 8.662   0.75 55.12  ? 301 A1AI3 L CAF 1 
HETATM 6775 C  CAE . A1AI3 N 2 .   ? 6.958   -50.466 8.546   0.75 59.03  ? 301 A1AI3 L CAE 1 
HETATM 6776 C  CAD . A1AI3 N 2 .   ? 7.715   -50.865 7.288   0.75 53.88  ? 301 A1AI3 L CAD 1 
HETATM 6777 C  CAC . A1AI3 N 2 .   ? 9.096   -51.329 7.714   0.75 59.80  ? 301 A1AI3 L CAC 1 
HETATM 6778 O  OAO . A1AI3 N 2 .   ? 9.254   -52.048 8.683   0.75 60.82  ? 301 A1AI3 L OAO 1 
HETATM 6779 N  N   . A1AI3 N 2 .   ? 10.097  -50.899 6.980   0.75 67.99  ? 301 A1AI3 L N   1 
HETATM 6780 C  CA  . A1AI3 N 2 .   ? 11.479  -51.241 7.280   0.75 53.84  ? 301 A1AI3 L CA  1 
HETATM 6781 C  C   . A1AI3 N 2 .   ? 12.332  -50.189 6.584   0.75 61.39  ? 301 A1AI3 L C   1 
HETATM 6782 O  OXT . A1AI3 N 2 .   ? 12.361  -50.336 5.351   0.75 40.70  ? 301 A1AI3 L OXT 1 
HETATM 6783 O  O   . A1AI3 N 2 .   ? 13.070  -49.433 7.231   0.75 61.89  ? 301 A1AI3 L O   1 
HETATM 6784 C  CB  . A1AI3 N 2 .   ? 11.787  -52.615 6.685   0.75 45.90  ? 301 A1AI3 L CB  1 
HETATM 6785 C  CAL . A1AI3 N 2 .   ? 13.236  -52.731 6.234   0.75 43.25  ? 301 A1AI3 L CAL 1 
HETATM 6786 O  OAQ . A1AI3 N 2 .   ? 13.464  -52.033 5.020   0.75 36.68  ? 301 A1AI3 L OAQ 1 
HETATM 6787 CO CO  . CO    O 3 .   ? 12.578  -47.621 6.422   1.00 34.11  ? 302 CO    L CO  1 
HETATM 6788 FE FE  . FE    P 5 .   ? 15.196  -50.063 5.524   1.00 37.51  ? 303 FE    L FE  1 
HETATM 6789 S  S   . SO4   Q 4 .   ? 17.265  -30.648 -6.006  1.00 90.85  ? 304 SO4   L S   1 
HETATM 6790 O  O1  . SO4   Q 4 .   ? 16.154  -31.519 -6.415  1.00 69.24  ? 304 SO4   L O1  1 
HETATM 6791 O  O2  . SO4   Q 4 .   ? 18.094  -30.339 -7.163  1.00 77.14  ? 304 SO4   L O2  1 
HETATM 6792 O  O3  . SO4   Q 4 .   ? 18.103  -31.321 -5.010  1.00 83.65  ? 304 SO4   L O3  1 
HETATM 6793 O  O4  . SO4   Q 4 .   ? 16.720  -29.419 -5.442  1.00 74.66  ? 304 SO4   L O4  1 
HETATM 6794 O  O   . HOH   R 6 .   ? 24.512  -25.571 3.456   1.00 42.56  ? 401 HOH   X O   1 
HETATM 6795 O  O   . HOH   R 6 .   ? 30.060  -5.286  -15.413 1.00 47.54  ? 402 HOH   X O   1 
HETATM 6796 O  O   . HOH   R 6 .   ? 15.522  -4.665  41.498  1.00 39.33  ? 403 HOH   X O   1 
HETATM 6797 O  O   . HOH   R 6 .   ? 33.783  7.081   10.745  1.00 43.99  ? 404 HOH   X O   1 
HETATM 6798 O  O   . HOH   R 6 .   ? 25.322  -15.654 -6.617  1.00 45.44  ? 405 HOH   X O   1 
HETATM 6799 O  O   . HOH   R 6 .   ? 27.779  -13.873 16.377  1.00 39.83  ? 406 HOH   X O   1 
HETATM 6800 O  O   . HOH   R 6 .   ? 18.396  -8.596  15.057  1.00 33.31  ? 407 HOH   X O   1 
HETATM 6801 O  O   . HOH   R 6 .   ? 12.418  7.602   6.602   1.00 38.96  ? 408 HOH   X O   1 
HETATM 6802 O  O   . HOH   R 6 .   ? 34.297  -14.749 -0.519  1.00 42.20  ? 409 HOH   X O   1 
HETATM 6803 O  O   . HOH   R 6 .   ? 11.002  -13.886 5.730   1.00 33.61  ? 410 HOH   X O   1 
HETATM 6804 O  O   . HOH   R 6 .   ? 1.498   -5.828  1.310   1.00 31.67  ? 411 HOH   X O   1 
HETATM 6805 O  O   . HOH   R 6 .   ? 10.254  -7.913  23.976  1.00 39.49  ? 412 HOH   X O   1 
HETATM 6806 O  O   . HOH   R 6 .   ? 5.139   5.302   12.024  1.00 45.02  ? 413 HOH   X O   1 
HETATM 6807 O  O   . HOH   R 6 .   ? -2.926  14.553  5.830   1.00 44.16  ? 414 HOH   X O   1 
HETATM 6808 O  O   . HOH   R 6 .   ? 13.671  8.186   -8.144  1.00 40.14  ? 415 HOH   X O   1 
HETATM 6809 O  O   . HOH   R 6 .   ? 7.550   -15.605 6.926   1.00 46.80  ? 416 HOH   X O   1 
HETATM 6810 O  O   . HOH   R 6 .   ? 34.780  2.603   2.875   1.00 34.47  ? 417 HOH   X O   1 
HETATM 6811 O  O   . HOH   R 6 .   ? 22.600  0.303   6.655   1.00 40.77  ? 418 HOH   X O   1 
HETATM 6812 O  O   . HOH   R 6 .   ? 16.130  -11.591 10.090  1.00 31.18  ? 419 HOH   X O   1 
HETATM 6813 O  O   . HOH   R 6 .   ? 16.490  -6.765  13.901  1.00 36.17  ? 420 HOH   X O   1 
HETATM 6814 O  O   . HOH   R 6 .   ? 12.865  -1.857  28.729  1.00 42.71  ? 421 HOH   X O   1 
HETATM 6815 O  O   . HOH   R 6 .   ? 39.771  -6.381  1.112   1.00 55.20  ? 422 HOH   X O   1 
HETATM 6816 O  O   . HOH   R 6 .   ? 17.692  3.587   -12.548 1.00 46.47  ? 423 HOH   X O   1 
HETATM 6817 O  O   . HOH   R 6 .   ? 4.204   -3.924  -5.608  1.00 40.02  ? 424 HOH   X O   1 
HETATM 6818 O  O   . HOH   R 6 .   ? 32.377  7.833   6.386   1.00 38.94  ? 425 HOH   X O   1 
HETATM 6819 O  O   . HOH   R 6 .   ? 14.489  10.032  8.880   1.00 35.21  ? 426 HOH   X O   1 
HETATM 6820 O  O   . HOH   R 6 .   ? 25.926  -2.270  18.457  1.00 41.93  ? 427 HOH   X O   1 
HETATM 6821 O  O   . HOH   R 6 .   ? 11.959  11.580  -10.267 1.00 46.32  ? 428 HOH   X O   1 
HETATM 6822 O  O   . HOH   R 6 .   ? 16.159  -20.517 6.906   1.00 39.90  ? 429 HOH   X O   1 
HETATM 6823 O  O   . HOH   R 6 .   ? 18.441  -8.951  17.765  1.00 38.50  ? 430 HOH   X O   1 
HETATM 6824 O  O   . HOH   R 6 .   ? 5.349   -16.136 9.401   1.00 40.46  ? 431 HOH   X O   1 
HETATM 6825 O  O   . HOH   R 6 .   ? 21.568  -22.025 8.849   1.00 42.03  ? 432 HOH   X O   1 
HETATM 6826 O  O   . HOH   R 6 .   ? 34.674  -11.410 1.982   1.00 35.73  ? 433 HOH   X O   1 
HETATM 6827 O  O   . HOH   R 6 .   ? 13.546  11.051  2.283   1.00 40.79  ? 434 HOH   X O   1 
HETATM 6828 O  O   . HOH   R 6 .   ? 32.867  10.440  2.485   1.00 42.76  ? 435 HOH   X O   1 
HETATM 6829 O  O   . HOH   R 6 .   ? 42.932  -1.440  -8.477  1.00 53.63  ? 436 HOH   X O   1 
HETATM 6830 O  O   . HOH   R 6 .   ? 32.789  -10.036 -9.007  1.00 44.89  ? 437 HOH   X O   1 
HETATM 6831 O  O   . HOH   R 6 .   ? 37.110  -4.461  -7.431  1.00 38.53  ? 438 HOH   X O   1 
HETATM 6832 O  O   . HOH   R 6 .   ? 10.371  6.203   7.573   1.00 36.36  ? 439 HOH   X O   1 
HETATM 6833 O  O   . HOH   R 6 .   ? 18.344  16.000  12.385  1.00 43.01  ? 440 HOH   X O   1 
HETATM 6834 O  O   . HOH   R 6 .   ? 3.067   -8.678  13.934  1.00 43.91  ? 441 HOH   X O   1 
HETATM 6835 O  O   . HOH   R 6 .   ? 4.577   -12.787 6.251   1.00 44.40  ? 442 HOH   X O   1 
HETATM 6836 O  O   . HOH   R 6 .   ? 21.871  9.527   20.195  1.00 42.58  ? 443 HOH   X O   1 
HETATM 6837 O  O   . HOH   R 6 .   ? 14.426  3.465   23.554  1.00 36.66  ? 444 HOH   X O   1 
HETATM 6838 O  O   . HOH   R 6 .   ? 38.671  -0.257  -8.845  1.00 42.72  ? 445 HOH   X O   1 
HETATM 6839 O  O   . HOH   R 6 .   ? 19.417  9.882   -8.154  1.00 42.54  ? 446 HOH   X O   1 
HETATM 6840 O  O   . HOH   R 6 .   ? 22.504  15.741  -8.290  1.00 48.39  ? 447 HOH   X O   1 
HETATM 6841 O  O   . HOH   R 6 .   ? 24.642  -6.842  -14.965 1.00 41.39  ? 448 HOH   X O   1 
HETATM 6842 O  O   . HOH   R 6 .   ? 31.347  14.256  4.701   1.00 44.04  ? 449 HOH   X O   1 
HETATM 6843 O  O   . HOH   R 6 .   ? 33.099  -7.728  -10.795 1.00 46.62  ? 450 HOH   X O   1 
HETATM 6844 O  O   . HOH   R 6 .   ? 2.272   -4.841  3.771   1.00 35.93  ? 451 HOH   X O   1 
HETATM 6845 O  O   . HOH   R 6 .   ? 34.275  8.310   8.222   1.00 42.84  ? 452 HOH   X O   1 
HETATM 6846 O  O   . HOH   R 6 .   ? 2.579   -8.778  -1.590  1.00 33.07  ? 453 HOH   X O   1 
HETATM 6847 O  O   . HOH   R 6 .   ? 17.495  -6.574  5.300   1.00 33.52  ? 454 HOH   X O   1 
HETATM 6848 O  O   . HOH   R 6 .   ? 27.455  -3.652  11.728  1.00 39.87  ? 455 HOH   X O   1 
HETATM 6849 O  O   . HOH   R 6 .   ? 28.167  -19.340 8.055   1.00 40.36  ? 456 HOH   X O   1 
HETATM 6850 O  O   . HOH   R 6 .   ? 19.199  -20.093 17.448  1.00 47.38  ? 457 HOH   X O   1 
HETATM 6851 O  O   . HOH   R 6 .   ? 18.851  15.716  -5.117  1.00 41.27  ? 458 HOH   X O   1 
HETATM 6852 O  O   . HOH   R 6 .   ? 7.245   -3.074  9.756   1.00 38.39  ? 459 HOH   X O   1 
HETATM 6853 O  O   . HOH   R 6 .   ? 22.100  11.497  6.637   1.00 39.07  ? 460 HOH   X O   1 
HETATM 6854 O  O   . HOH   R 6 .   ? 8.955   -11.890 0.449   1.00 36.25  ? 461 HOH   X O   1 
HETATM 6855 O  O   . HOH   R 6 .   ? 6.590   13.461  10.287  1.00 39.04  ? 462 HOH   X O   1 
HETATM 6856 O  O   . HOH   R 6 .   ? 4.731   -8.690  5.168   1.00 38.13  ? 463 HOH   X O   1 
HETATM 6857 O  O   . HOH   R 6 .   ? 13.021  12.715  9.150   1.00 41.24  ? 464 HOH   X O   1 
HETATM 6858 O  O   . HOH   R 6 .   ? 16.347  -12.059 22.604  1.00 43.09  ? 465 HOH   X O   1 
HETATM 6859 O  O   . HOH   R 6 .   ? 27.479  -18.403 12.299  1.00 44.80  ? 466 HOH   X O   1 
HETATM 6860 O  O   . HOH   R 6 .   ? 24.079  -4.247  6.433   1.00 37.27  ? 467 HOH   X O   1 
HETATM 6861 O  O   . HOH   R 6 .   ? 31.377  1.963   16.398  1.00 45.60  ? 468 HOH   X O   1 
HETATM 6862 O  O   . HOH   R 6 .   ? 20.425  -3.636  -14.053 1.00 44.68  ? 469 HOH   X O   1 
HETATM 6863 O  O   . HOH   R 6 .   ? 13.302  -10.953 6.797   1.00 35.15  ? 470 HOH   X O   1 
HETATM 6864 O  O   . HOH   R 6 .   ? 26.543  -11.806 -5.898  1.00 51.49  ? 471 HOH   X O   1 
HETATM 6865 O  O   . HOH   R 6 .   ? 40.245  -3.456  -1.298  1.00 43.86  ? 472 HOH   X O   1 
HETATM 6866 O  O   . HOH   R 6 .   ? 14.555  -15.060 4.106   1.00 38.21  ? 473 HOH   X O   1 
HETATM 6867 O  O   . HOH   R 6 .   ? 34.967  -13.760 3.203   1.00 46.14  ? 474 HOH   X O   1 
HETATM 6868 O  O   . HOH   R 6 .   ? 35.611  10.931  1.677   1.00 42.98  ? 475 HOH   X O   1 
HETATM 6869 O  O   . HOH   R 6 .   ? 7.961   16.657  4.058   1.00 40.04  ? 476 HOH   X O   1 
HETATM 6870 O  O   . HOH   R 6 .   ? 33.255  12.385  4.381   1.00 37.91  ? 477 HOH   X O   1 
HETATM 6871 O  O   . HOH   R 6 .   ? 19.075  -4.131  37.176  1.00 43.88  ? 478 HOH   X O   1 
HETATM 6872 O  O   . HOH   R 6 .   ? 28.678  -17.303 14.297  1.00 43.18  ? 479 HOH   X O   1 
HETATM 6873 O  O   . HOH   R 6 .   ? 14.497  21.530  14.778  1.00 57.59  ? 480 HOH   X O   1 
HETATM 6874 O  O   . HOH   R 6 .   ? 7.416   4.531   -9.762  1.00 41.78  ? 481 HOH   X O   1 
HETATM 6875 O  O   . HOH   R 6 .   ? 16.544  -1.178  39.959  1.00 42.37  ? 482 HOH   X O   1 
HETATM 6876 O  O   . HOH   R 6 .   ? 27.166  -11.497 -11.572 1.00 40.93  ? 483 HOH   X O   1 
HETATM 6877 O  O   . HOH   R 6 .   ? 6.284   2.036   14.400  1.00 41.89  ? 484 HOH   X O   1 
HETATM 6878 O  O   . HOH   R 6 .   ? 1.764   -4.847  -3.777  1.00 38.92  ? 485 HOH   X O   1 
HETATM 6879 O  O   . HOH   R 6 .   ? 26.918  14.884  -11.905 1.00 54.14  ? 486 HOH   X O   1 
HETATM 6880 O  O   . HOH   R 6 .   ? 14.172  -9.866  9.208   1.00 32.29  ? 487 HOH   X O   1 
HETATM 6881 O  O   . HOH   R 6 .   ? 31.229  6.139   18.288  1.00 46.55  ? 488 HOH   X O   1 
HETATM 6882 O  O   . HOH   R 6 .   ? 5.843   15.671  18.201  1.00 43.58  ? 489 HOH   X O   1 
HETATM 6883 O  O   . HOH   R 6 .   ? 5.328   12.617  20.297  1.00 42.89  ? 490 HOH   X O   1 
HETATM 6884 O  O   . HOH   R 6 .   ? 12.493  -6.918  25.228  1.00 48.27  ? 491 HOH   X O   1 
HETATM 6885 O  O   . HOH   R 6 .   ? 4.676   -12.490 -5.536  1.00 46.45  ? 492 HOH   X O   1 
HETATM 6886 O  O   . HOH   R 6 .   ? 21.000  3.677   6.717   1.00 35.17  ? 493 HOH   X O   1 
HETATM 6887 O  O   . HOH   R 6 .   ? 12.361  -3.178  1.567   1.00 30.26  ? 494 HOH   X O   1 
HETATM 6888 O  O   . HOH   R 6 .   ? 26.067  -22.763 7.966   1.00 54.29  ? 495 HOH   X O   1 
HETATM 6889 O  O   . HOH   R 6 .   ? 28.593  19.672  12.625  1.00 43.00  ? 496 HOH   X O   1 
HETATM 6890 O  O   . HOH   R 6 .   ? 28.783  9.710   19.815  1.00 44.67  ? 497 HOH   X O   1 
HETATM 6891 O  O   . HOH   R 6 .   ? -1.141  -10.902 2.160   1.00 35.77  ? 498 HOH   X O   1 
HETATM 6892 O  O   . HOH   R 6 .   ? 14.209  -3.785  32.504  1.00 44.83  ? 499 HOH   X O   1 
HETATM 6893 O  O   . HOH   R 6 .   ? 21.756  13.983  3.647   1.00 43.92  ? 500 HOH   X O   1 
HETATM 6894 O  O   . HOH   R 6 .   ? 37.639  -7.754  4.274   1.00 46.08  ? 501 HOH   X O   1 
HETATM 6895 O  O   . HOH   R 6 .   ? 37.768  7.747   -4.058  1.00 61.35  ? 502 HOH   X O   1 
HETATM 6896 O  O   . HOH   R 6 .   ? 22.747  1.103   9.401   1.00 46.29  ? 503 HOH   X O   1 
HETATM 6897 O  O   . HOH   R 6 .   ? 26.528  1.725   24.199  1.00 41.35  ? 504 HOH   X O   1 
HETATM 6898 O  O   . HOH   R 6 .   ? 0.632   -0.049  8.176   1.00 46.70  ? 505 HOH   X O   1 
HETATM 6899 O  O   . HOH   R 6 .   ? 7.651   -12.377 2.958   1.00 34.91  ? 506 HOH   X O   1 
HETATM 6900 O  O   . HOH   R 6 .   ? 7.351   -1.922  -9.605  1.00 37.21  ? 507 HOH   X O   1 
HETATM 6901 O  O   . HOH   R 6 .   ? 18.382  2.223   -14.672 1.00 44.75  ? 508 HOH   X O   1 
HETATM 6902 O  O   . HOH   R 6 .   ? -2.881  -2.897  7.891   1.00 45.51  ? 509 HOH   X O   1 
HETATM 6903 O  O   . HOH   R 6 .   ? 11.471  -14.660 -0.062  1.00 45.75  ? 510 HOH   X O   1 
HETATM 6904 O  O   . HOH   R 6 .   ? 34.466  17.357  -3.113  1.00 44.03  ? 511 HOH   X O   1 
HETATM 6905 O  O   . HOH   R 6 .   ? 2.457   -7.275  5.361   1.00 46.33  ? 512 HOH   X O   1 
HETATM 6906 O  O   . HOH   R 6 .   ? 23.521  -15.558 -2.815  1.00 53.88  ? 513 HOH   X O   1 
HETATM 6907 O  O   . HOH   R 6 .   ? 31.883  -23.700 0.373   1.00 46.28  ? 514 HOH   X O   1 
HETATM 6908 O  O   . HOH   R 6 .   ? 23.934  18.103  2.640   1.00 45.19  ? 515 HOH   X O   1 
HETATM 6909 O  O   . HOH   R 6 .   ? 30.258  -11.608 10.782  1.00 45.24  ? 516 HOH   X O   1 
HETATM 6910 O  O   . HOH   R 6 .   ? 37.851  0.443   -12.281 1.00 46.54  ? 517 HOH   X O   1 
HETATM 6911 O  O   . HOH   R 6 .   ? 1.053   -15.341 -0.231  1.00 42.95  ? 518 HOH   X O   1 
HETATM 6912 O  O   . HOH   R 6 .   ? 14.009  -17.456 5.131   1.00 46.77  ? 519 HOH   X O   1 
HETATM 6913 O  O   . HOH   R 6 .   ? 34.939  1.781   -11.056 1.00 48.33  ? 520 HOH   X O   1 
HETATM 6914 O  O   . HOH   R 6 .   ? 40.547  10.679  8.235   1.00 47.44  ? 521 HOH   X O   1 
HETATM 6915 O  O   . HOH   R 6 .   ? 20.881  15.376  14.269  1.00 61.23  ? 522 HOH   X O   1 
HETATM 6916 O  O   . HOH   R 6 .   ? 0.247   -8.748  4.704   1.00 40.62  ? 523 HOH   X O   1 
HETATM 6917 O  O   . HOH   R 6 .   ? 9.677   -11.022 20.086  1.00 45.50  ? 524 HOH   X O   1 
HETATM 6918 O  O   . HOH   R 6 .   ? 37.253  10.486  -4.673  1.00 59.19  ? 525 HOH   X O   1 
HETATM 6919 O  O   . HOH   R 6 .   ? 18.075  -22.110 6.021   1.00 45.12  ? 526 HOH   X O   1 
HETATM 6920 O  O   . HOH   R 6 .   ? 31.105  -18.688 7.342   1.00 44.54  ? 527 HOH   X O   1 
HETATM 6921 O  O   . HOH   R 6 .   ? -0.125  -2.331  7.734   1.00 44.55  ? 528 HOH   X O   1 
HETATM 6922 O  O   . HOH   R 6 .   ? 31.169  -12.041 -9.701  1.00 46.21  ? 529 HOH   X O   1 
HETATM 6923 O  O   . HOH   R 6 .   ? 27.901  -21.813 9.337   1.00 45.20  ? 530 HOH   X O   1 
HETATM 6924 O  O   . HOH   R 6 .   ? 19.976  15.368  2.213   1.00 54.05  ? 531 HOH   X O   1 
HETATM 6925 O  O   . HOH   S 6 .   ? -17.752 -10.529 12.212  1.00 38.56  ? 401 HOH   F O   1 
HETATM 6926 O  O   . HOH   S 6 .   ? -25.409 -33.998 26.203  1.00 48.61  ? 402 HOH   F O   1 
HETATM 6927 O  O   . HOH   S 6 .   ? -1.056  -11.937 25.394  1.00 31.86  ? 403 HOH   F O   1 
HETATM 6928 O  O   . HOH   S 6 .   ? -26.576 -28.313 36.431  1.00 42.62  ? 404 HOH   F O   1 
HETATM 6929 O  O   . HOH   S 6 .   ? 18.276  -38.068 29.767  1.00 50.96  ? 405 HOH   F O   1 
HETATM 6930 O  O   . HOH   S 6 .   ? -9.355  -5.054  26.706  1.00 41.14  ? 406 HOH   F O   1 
HETATM 6931 O  O   . HOH   S 6 .   ? 12.953  -6.341  31.505  1.00 42.99  ? 407 HOH   F O   1 
HETATM 6932 O  O   . HOH   S 6 .   ? -23.786 -15.869 24.871  1.00 40.28  ? 408 HOH   F O   1 
HETATM 6933 O  O   . HOH   S 6 .   ? -4.339  -40.432 29.946  1.00 40.06  ? 409 HOH   F O   1 
HETATM 6934 O  O   . HOH   S 6 .   ? -8.710  -27.103 47.810  1.00 43.06  ? 410 HOH   F O   1 
HETATM 6935 O  O   . HOH   S 6 .   ? 4.434   -28.751 32.727  1.00 38.30  ? 411 HOH   F O   1 
HETATM 6936 O  O   . HOH   S 6 .   ? -2.902  -9.811  35.393  1.00 41.35  ? 412 HOH   F O   1 
HETATM 6937 O  O   . HOH   S 6 .   ? 5.201   -7.964  42.985  1.00 44.91  ? 413 HOH   F O   1 
HETATM 6938 O  O   . HOH   S 6 .   ? 17.012  6.041   34.148  1.00 40.49  ? 414 HOH   F O   1 
HETATM 6939 O  O   . HOH   S 6 .   ? -2.264  -19.277 14.730  1.00 34.24  ? 415 HOH   F O   1 
HETATM 6940 O  O   . HOH   S 6 .   ? -8.637  -41.361 40.840  1.00 46.74  ? 416 HOH   F O   1 
HETATM 6941 O  O   . HOH   S 6 .   ? -2.976  -15.099 20.477  1.00 31.16  ? 417 HOH   F O   1 
HETATM 6942 O  O   . HOH   S 6 .   ? -15.899 -8.912  20.328  1.00 44.14  ? 418 HOH   F O   1 
HETATM 6943 O  O   . HOH   S 6 .   ? 2.443   -33.589 35.000  1.00 40.80  ? 419 HOH   F O   1 
HETATM 6944 O  O   . HOH   S 6 .   ? 10.711  -12.556 35.198  1.00 37.88  ? 420 HOH   F O   1 
HETATM 6945 O  O   . HOH   S 6 .   ? 4.938   -27.502 36.398  1.00 35.63  ? 421 HOH   F O   1 
HETATM 6946 O  O   . HOH   S 6 .   ? -16.424 -21.653 39.907  1.00 34.97  ? 422 HOH   F O   1 
HETATM 6947 O  O   . HOH   S 6 .   ? 3.342   -21.520 12.282  1.00 43.51  ? 423 HOH   F O   1 
HETATM 6948 O  O   . HOH   S 6 .   ? -10.927 -22.275 43.721  1.00 37.69  ? 424 HOH   F O   1 
HETATM 6949 O  O   . HOH   S 6 .   ? 0.196   -35.691 15.948  1.00 41.56  ? 425 HOH   F O   1 
HETATM 6950 O  O   . HOH   S 6 .   ? 5.549   -14.912 12.942  1.00 36.36  ? 426 HOH   F O   1 
HETATM 6951 O  O   . HOH   S 6 .   ? -12.494 -26.573 44.969  1.00 39.53  ? 427 HOH   F O   1 
HETATM 6952 O  O   . HOH   S 6 .   ? -2.856  -25.183 13.759  1.00 34.86  ? 428 HOH   F O   1 
HETATM 6953 O  O   . HOH   S 6 .   ? -5.735  -21.578 32.510  1.00 38.76  ? 429 HOH   F O   1 
HETATM 6954 O  O   . HOH   S 6 .   ? -7.839  -13.218 12.603  1.00 44.33  ? 430 HOH   F O   1 
HETATM 6955 O  O   . HOH   S 6 .   ? -3.097  -44.353 31.205  1.00 46.06  ? 431 HOH   F O   1 
HETATM 6956 O  O   . HOH   S 6 .   ? -9.906  -17.948 45.146  1.00 44.16  ? 432 HOH   F O   1 
HETATM 6957 O  O   . HOH   S 6 .   ? 5.472   -30.063 14.813  1.00 32.11  ? 433 HOH   F O   1 
HETATM 6958 O  O   . HOH   S 6 .   ? 0.301   -9.579  25.908  1.00 34.96  ? 434 HOH   F O   1 
HETATM 6959 O  O   . HOH   S 6 .   ? -25.542 -25.682 25.778  1.00 50.16  ? 435 HOH   F O   1 
HETATM 6960 O  O   . HOH   S 6 .   ? -11.304 -40.319 27.372  1.00 44.68  ? 436 HOH   F O   1 
HETATM 6961 O  O   . HOH   S 6 .   ? 18.511  -25.646 38.833  1.00 50.13  ? 437 HOH   F O   1 
HETATM 6962 O  O   . HOH   S 6 .   ? 18.650  -37.499 22.499  1.00 37.39  ? 438 HOH   F O   1 
HETATM 6963 O  O   . HOH   S 6 .   ? -21.615 -15.451 28.509  1.00 35.66  ? 439 HOH   F O   1 
HETATM 6964 O  O   . HOH   S 6 .   ? 0.470   -14.390 25.468  1.00 33.75  ? 440 HOH   F O   1 
HETATM 6965 O  O   . HOH   S 6 .   ? 3.070   -35.238 40.567  1.00 44.58  ? 441 HOH   F O   1 
HETATM 6966 O  O   . HOH   S 6 .   ? -3.773  -40.123 39.452  1.00 40.45  ? 442 HOH   F O   1 
HETATM 6967 O  O   . HOH   S 6 .   ? 1.985   -30.472 12.245  1.00 34.51  ? 443 HOH   F O   1 
HETATM 6968 O  O   . HOH   S 6 .   ? -24.132 -16.800 35.165  1.00 43.04  ? 444 HOH   F O   1 
HETATM 6969 O  O   . HOH   S 6 .   ? 6.002   -26.334 44.151  1.00 42.81  ? 445 HOH   F O   1 
HETATM 6970 O  O   . HOH   S 6 .   ? -0.753  -45.357 34.116  1.00 42.81  ? 446 HOH   F O   1 
HETATM 6971 O  O   . HOH   S 6 .   ? 12.935  -30.683 35.245  1.00 39.02  ? 447 HOH   F O   1 
HETATM 6972 O  O   . HOH   S 6 .   ? -1.626  -41.955 23.383  1.00 47.70  ? 448 HOH   F O   1 
HETATM 6973 O  O   . HOH   S 6 .   ? 6.152   -28.008 30.883  1.00 37.82  ? 449 HOH   F O   1 
HETATM 6974 O  O   . HOH   S 6 .   ? -4.986  -21.052 23.931  1.00 35.12  ? 450 HOH   F O   1 
HETATM 6975 O  O   . HOH   S 6 .   ? 3.279   -17.007 10.811  1.00 38.62  ? 451 HOH   F O   1 
HETATM 6976 O  O   . HOH   S 6 .   ? 5.251   -15.642 43.151  1.00 43.37  ? 452 HOH   F O   1 
HETATM 6977 O  O   . HOH   S 6 .   ? -7.986  -14.053 33.434  1.00 41.28  ? 453 HOH   F O   1 
HETATM 6978 O  O   . HOH   S 6 .   ? -4.390  -3.970  17.410  1.00 45.73  ? 454 HOH   F O   1 
HETATM 6979 O  O   . HOH   S 6 .   ? -1.590  -27.394 41.128  1.00 39.69  ? 455 HOH   F O   1 
HETATM 6980 O  O   . HOH   S 6 .   ? 10.191  -18.015 16.799  1.00 46.70  ? 456 HOH   F O   1 
HETATM 6981 O  O   . HOH   S 6 .   ? 7.157   -29.184 37.911  1.00 38.54  ? 457 HOH   F O   1 
HETATM 6982 O  O   . HOH   S 6 .   ? 16.431  3.488   36.966  1.00 54.08  ? 458 HOH   F O   1 
HETATM 6983 O  O   . HOH   S 6 .   ? 9.510   -36.911 36.840  1.00 45.80  ? 459 HOH   F O   1 
HETATM 6984 O  O   . HOH   S 6 .   ? -16.734 -36.883 22.643  1.00 45.47  ? 460 HOH   F O   1 
HETATM 6985 O  O   . HOH   S 6 .   ? -24.928 -20.102 36.943  1.00 43.13  ? 461 HOH   F O   1 
HETATM 6986 O  O   . HOH   S 6 .   ? -11.080 -20.401 45.588  1.00 43.23  ? 462 HOH   F O   1 
HETATM 6987 O  O   . HOH   S 6 .   ? -26.238 -25.664 32.906  1.00 42.45  ? 463 HOH   F O   1 
HETATM 6988 O  O   . HOH   S 6 .   ? -20.749 -28.832 43.566  1.00 47.77  ? 464 HOH   F O   1 
HETATM 6989 O  O   . HOH   S 6 .   ? 11.730  3.725   35.165  1.00 43.03  ? 465 HOH   F O   1 
HETATM 6990 O  O   . HOH   S 6 .   ? -8.115  -39.387 34.309  1.00 43.33  ? 466 HOH   F O   1 
HETATM 6991 O  O   . HOH   S 6 .   ? -12.827 -6.068  21.895  1.00 42.58  ? 467 HOH   F O   1 
HETATM 6992 O  O   . HOH   S 6 .   ? 8.097   -4.760  41.049  1.00 51.99  ? 468 HOH   F O   1 
HETATM 6993 O  O   . HOH   S 6 .   ? 6.614   -22.716 22.333  1.00 36.21  ? 469 HOH   F O   1 
HETATM 6994 O  O   . HOH   S 6 .   ? 6.523   -28.276 16.588  1.00 36.05  ? 470 HOH   F O   1 
HETATM 6995 O  O   . HOH   S 6 .   ? -27.821 -32.500 32.414  1.00 55.23  ? 471 HOH   F O   1 
HETATM 6996 O  O   . HOH   S 6 .   ? -14.971 -26.517 46.701  1.00 40.87  ? 472 HOH   F O   1 
HETATM 6997 O  O   . HOH   S 6 .   ? -22.006 -13.171 27.093  1.00 40.46  ? 473 HOH   F O   1 
HETATM 6998 O  O   . HOH   S 6 .   ? -31.365 -30.987 27.309  1.00 66.09  ? 474 HOH   F O   1 
HETATM 6999 O  O   . HOH   S 6 .   ? 3.450   -4.874  23.655  1.00 42.82  ? 475 HOH   F O   1 
HETATM 7000 O  O   . HOH   S 6 .   ? -6.267  -18.721 15.288  1.00 37.04  ? 476 HOH   F O   1 
HETATM 7001 O  O   . HOH   S 6 .   ? 11.434  -21.924 27.122  1.00 50.23  ? 477 HOH   F O   1 
HETATM 7002 O  O   . HOH   S 6 .   ? -1.392  -17.432 20.539  1.00 31.08  ? 478 HOH   F O   1 
HETATM 7003 O  O   . HOH   S 6 .   ? -4.165  -12.331 44.911  1.00 59.30  ? 479 HOH   F O   1 
HETATM 7004 O  O   . HOH   S 6 .   ? -4.246  -19.757 33.716  1.00 56.20  ? 480 HOH   F O   1 
HETATM 7005 O  O   . HOH   S 6 .   ? -8.638  -19.028 29.685  1.00 35.28  ? 481 HOH   F O   1 
HETATM 7006 O  O   . HOH   S 6 .   ? -19.820 -24.234 21.760  1.00 54.21  ? 482 HOH   F O   1 
HETATM 7007 O  O   . HOH   S 6 .   ? 4.075   -24.416 15.200  1.00 37.50  ? 483 HOH   F O   1 
HETATM 7008 O  O   . HOH   S 6 .   ? -2.425  -19.050 18.661  1.00 33.73  ? 484 HOH   F O   1 
HETATM 7009 O  O   . HOH   S 6 .   ? -23.177 -28.915 20.735  1.00 46.99  ? 485 HOH   F O   1 
HETATM 7010 O  O   . HOH   S 6 .   ? -12.313 -4.658  23.874  1.00 43.20  ? 486 HOH   F O   1 
HETATM 7011 O  O   . HOH   S 6 .   ? 9.915   -1.773  28.479  1.00 39.55  ? 487 HOH   F O   1 
HETATM 7012 O  O   . HOH   S 6 .   ? -11.073 -25.905 47.334  1.00 38.04  ? 488 HOH   F O   1 
HETATM 7013 O  O   . HOH   S 6 .   ? 13.291  -1.842  31.683  1.00 39.61  ? 489 HOH   F O   1 
HETATM 7014 O  O   . HOH   S 6 .   ? -3.381  -23.841 34.361  1.00 37.20  ? 490 HOH   F O   1 
HETATM 7015 O  O   . HOH   S 6 .   ? 2.801   -34.482 14.329  1.00 40.05  ? 491 HOH   F O   1 
HETATM 7016 O  O   . HOH   S 6 .   ? -1.874  -27.480 22.869  1.00 31.60  ? 492 HOH   F O   1 
HETATM 7017 O  O   . HOH   S 6 .   ? 11.742  -27.914 20.774  1.00 47.32  ? 493 HOH   F O   1 
HETATM 7018 O  O   . HOH   S 6 .   ? -2.120  -31.144 42.088  1.00 44.47  ? 494 HOH   F O   1 
HETATM 7019 O  O   . HOH   S 6 .   ? 6.230   -27.703 9.502   1.00 35.30  ? 495 HOH   F O   1 
HETATM 7020 O  O   . HOH   S 6 .   ? -3.590  -38.621 18.244  1.00 38.85  ? 496 HOH   F O   1 
HETATM 7021 O  O   . HOH   S 6 .   ? -20.682 -22.575 18.184  1.00 47.64  ? 497 HOH   F O   1 
HETATM 7022 O  O   . HOH   S 6 .   ? -18.417 -38.508 35.932  1.00 55.94  ? 498 HOH   F O   1 
HETATM 7023 O  O   . HOH   S 6 .   ? 1.322   -6.967  40.525  1.00 41.73  ? 499 HOH   F O   1 
HETATM 7024 O  O   . HOH   S 6 .   ? 18.053  -28.567 15.417  1.00 39.57  ? 500 HOH   F O   1 
HETATM 7025 O  O   . HOH   S 6 .   ? -3.061  -31.095 9.243   1.00 41.62  ? 501 HOH   F O   1 
HETATM 7026 O  O   . HOH   S 6 .   ? -0.569  -23.286 13.343  1.00 36.89  ? 502 HOH   F O   1 
HETATM 7027 O  O   . HOH   S 6 .   ? -13.574 -41.079 26.087  1.00 44.54  ? 503 HOH   F O   1 
HETATM 7028 O  O   . HOH   S 6 .   ? -5.336  -23.211 13.217  1.00 45.29  ? 504 HOH   F O   1 
HETATM 7029 O  O   . HOH   S 6 .   ? 13.287  -27.663 16.517  1.00 54.51  ? 505 HOH   F O   1 
HETATM 7030 O  O   . HOH   S 6 .   ? -13.501 -9.936  28.479  1.00 44.33  ? 506 HOH   F O   1 
HETATM 7031 O  O   . HOH   S 6 .   ? -14.233 -34.139 49.819  1.00 44.83  ? 507 HOH   F O   1 
HETATM 7032 O  O   . HOH   S 6 .   ? 6.471   -25.824 15.181  1.00 45.13  ? 508 HOH   F O   1 
HETATM 7033 O  O   . HOH   S 6 .   ? -16.808 -21.014 17.871  1.00 42.83  ? 509 HOH   F O   1 
HETATM 7034 O  O   . HOH   S 6 .   ? 15.335  -40.383 30.011  1.00 42.73  ? 510 HOH   F O   1 
HETATM 7035 O  O   . HOH   S 6 .   ? -1.237  -21.196 12.505  1.00 39.14  ? 511 HOH   F O   1 
HETATM 7036 O  O   . HOH   S 6 .   ? 7.324   -9.467  20.358  1.00 45.21  ? 512 HOH   F O   1 
HETATM 7037 O  O   . HOH   S 6 .   ? -6.100  -16.934 13.451  1.00 44.88  ? 513 HOH   F O   1 
HETATM 7038 O  O   . HOH   S 6 .   ? 3.507   -32.838 12.330  1.00 38.67  ? 514 HOH   F O   1 
HETATM 7039 O  O   . HOH   S 6 .   ? 7.202   -26.342 12.760  1.00 39.80  ? 515 HOH   F O   1 
HETATM 7040 O  O   . HOH   S 6 .   ? -15.349 -32.219 50.441  1.00 46.66  ? 516 HOH   F O   1 
HETATM 7041 O  O   . HOH   S 6 .   ? 11.349  -27.198 18.402  1.00 44.52  ? 517 HOH   F O   1 
HETATM 7042 O  O   . HOH   T 6 .   ? 35.964  -36.704 12.289  1.00 41.87  ? 401 HOH   L O   1 
HETATM 7043 O  O   . HOH   T 6 .   ? 25.710  -28.963 -5.887  1.00 46.45  ? 402 HOH   L O   1 
HETATM 7044 O  O   . HOH   T 6 .   ? 8.986   -53.431 17.477  1.00 40.51  ? 403 HOH   L O   1 
HETATM 7045 O  O   . HOH   T 6 .   ? 15.528  -50.137 -12.211 1.00 42.89  ? 404 HOH   L O   1 
HETATM 7046 O  O   . HOH   T 6 .   ? 10.869  -48.472 -2.537  1.00 31.87  ? 405 HOH   L O   1 
HETATM 7047 O  O   . HOH   T 6 .   ? -4.396  -70.570 -4.788  1.00 40.47  ? 406 HOH   L O   1 
HETATM 7048 O  O   . HOH   T 6 .   ? 9.455   -35.341 -8.546  1.00 46.79  ? 407 HOH   L O   1 
HETATM 7049 O  O   . HOH   T 6 .   ? 25.552  -36.740 19.522  1.00 40.13  ? 408 HOH   L O   1 
HETATM 7050 O  O   . HOH   T 6 .   ? 1.442   -60.866 2.217   1.00 42.55  ? 409 HOH   L O   1 
HETATM 7051 O  O   . HOH   T 6 .   ? 16.430  -47.784 15.735  1.00 40.86  ? 410 HOH   L O   1 
HETATM 7052 O  O   . HOH   T 6 .   ? 0.000   -53.223 0.000   0.50 40.57  ? 411 HOH   L O   1 
HETATM 7053 O  O   . HOH   T 6 .   ? 8.427   -35.913 -0.284  1.00 33.64  ? 412 HOH   L O   1 
HETATM 7054 O  O   . HOH   T 6 .   ? 9.319   -50.582 -3.548  1.00 35.38  ? 413 HOH   L O   1 
HETATM 7055 O  O   . HOH   T 6 .   ? 17.025  -56.841 -2.570  1.00 40.25  ? 414 HOH   L O   1 
HETATM 7056 O  O   . HOH   T 6 .   ? 12.819  -29.490 14.389  1.00 39.18  ? 415 HOH   L O   1 
HETATM 7057 O  O   . HOH   T 6 .   ? 3.656   -34.704 3.899   1.00 44.07  ? 416 HOH   L O   1 
HETATM 7058 O  O   . HOH   T 6 .   ? 35.626  -45.687 -8.691  1.00 52.78  ? 417 HOH   L O   1 
HETATM 7059 O  O   . HOH   T 6 .   ? 20.806  -46.560 19.076  1.00 40.95  ? 418 HOH   L O   1 
HETATM 7060 O  O   . HOH   T 6 .   ? 29.420  -38.379 -11.950 1.00 41.47  ? 419 HOH   L O   1 
HETATM 7061 O  O   . HOH   T 6 .   ? 17.603  -51.505 16.020  1.00 35.84  ? 420 HOH   L O   1 
HETATM 7062 O  O   . HOH   T 6 .   ? 10.644  -47.795 0.195   1.00 36.95  ? 421 HOH   L O   1 
HETATM 7063 O  O   . HOH   T 6 .   ? 29.513  -42.138 -10.094 1.00 37.83  ? 422 HOH   L O   1 
HETATM 7064 O  O   . HOH   T 6 .   ? 23.871  -50.321 22.372  1.00 44.90  ? 423 HOH   L O   1 
HETATM 7065 O  O   . HOH   T 6 .   ? 7.327   -59.987 6.904   1.00 37.81  ? 424 HOH   L O   1 
HETATM 7066 O  O   . HOH   T 6 .   ? 20.605  -58.623 17.684  1.00 42.69  ? 425 HOH   L O   1 
HETATM 7067 O  O   . HOH   T 6 .   ? 33.860  -49.933 0.719   1.00 33.20  ? 426 HOH   L O   1 
HETATM 7068 O  O   . HOH   T 6 .   ? 10.780  -42.259 -2.418  1.00 30.54  ? 427 HOH   L O   1 
HETATM 7069 O  O   . HOH   T 6 .   ? 26.623  -36.215 23.655  1.00 45.80  ? 428 HOH   L O   1 
HETATM 7070 O  O   . HOH   T 6 .   ? 17.419  -48.614 25.997  1.00 46.01  ? 429 HOH   L O   1 
HETATM 7071 O  O   . HOH   T 6 .   ? 7.103   -48.436 16.561  1.00 43.57  ? 430 HOH   L O   1 
HETATM 7072 O  O   . HOH   T 6 .   ? 1.356   -35.796 -0.032  1.00 40.16  ? 431 HOH   L O   1 
HETATM 7073 O  O   . HOH   T 6 .   ? 36.683  -33.184 -3.056  1.00 45.26  ? 432 HOH   L O   1 
HETATM 7074 O  O   . HOH   T 6 .   ? 7.645   -29.764 10.275  1.00 32.56  ? 433 HOH   L O   1 
HETATM 7075 O  O   . HOH   T 6 .   ? 29.497  -32.310 14.950  1.00 44.64  ? 434 HOH   L O   1 
HETATM 7076 O  O   . HOH   T 6 .   ? 0.000   -39.247 0.000   0.50 38.33  ? 435 HOH   L O   1 
HETATM 7077 O  O   . HOH   T 6 .   ? 18.538  -40.848 -14.442 1.00 45.02  ? 436 HOH   L O   1 
HETATM 7078 O  O   . HOH   T 6 .   ? 21.679  -47.629 4.437   1.00 40.10  ? 437 HOH   L O   1 
HETATM 7079 O  O   . HOH   T 6 .   ? 34.641  -33.575 -4.888  1.00 49.70  ? 438 HOH   L O   1 
HETATM 7080 O  O   . HOH   T 6 .   ? 10.469  -31.948 3.830   1.00 36.60  ? 439 HOH   L O   1 
HETATM 7081 O  O   . HOH   T 6 .   ? 7.847   -51.386 3.307   1.00 43.78  ? 440 HOH   L O   1 
HETATM 7082 O  O   . HOH   T 6 .   ? 34.162  -56.131 11.392  1.00 43.17  ? 441 HOH   L O   1 
HETATM 7083 O  O   . HOH   T 6 .   ? 42.141  -40.553 -0.475  1.00 41.93  ? 442 HOH   L O   1 
HETATM 7084 O  O   . HOH   T 6 .   ? 13.788  -47.209 15.557  1.00 34.57  ? 443 HOH   L O   1 
HETATM 7085 O  O   . HOH   T 6 .   ? 6.249   -33.165 12.538  1.00 33.00  ? 444 HOH   L O   1 
HETATM 7086 O  O   . HOH   T 6 .   ? 5.858   -35.978 12.160  1.00 36.27  ? 445 HOH   L O   1 
HETATM 7087 O  O   . HOH   T 6 .   ? 35.261  -52.876 8.188   1.00 40.57  ? 446 HOH   L O   1 
HETATM 7088 O  O   . HOH   T 6 .   ? 6.291   -44.963 -12.806 1.00 44.77  ? 447 HOH   L O   1 
HETATM 7089 O  O   . HOH   T 6 .   ? 21.273  -51.462 -2.542  1.00 40.70  ? 448 HOH   L O   1 
HETATM 7090 O  O   . HOH   T 6 .   ? 16.934  -62.895 8.583   1.00 43.23  ? 449 HOH   L O   1 
HETATM 7091 O  O   . HOH   T 6 .   ? 25.128  -53.024 13.603  1.00 38.56  ? 450 HOH   L O   1 
HETATM 7092 O  O   . HOH   T 6 .   ? 32.503  -56.944 4.077   1.00 42.13  ? 451 HOH   L O   1 
HETATM 7093 O  O   . HOH   T 6 .   ? 23.692  -62.752 1.437   1.00 59.92  ? 452 HOH   L O   1 
HETATM 7094 O  O   . HOH   T 6 .   ? 11.861  -51.670 22.548  1.00 38.57  ? 453 HOH   L O   1 
HETATM 7095 O  O   . HOH   T 6 .   ? 20.352  -31.514 20.301  1.00 45.27  ? 454 HOH   L O   1 
HETATM 7096 O  O   . HOH   T 6 .   ? 30.371  -44.689 21.954  1.00 40.63  ? 455 HOH   L O   1 
HETATM 7097 O  O   . HOH   T 6 .   ? 23.659  -59.295 -1.535  1.00 44.52  ? 456 HOH   L O   1 
HETATM 7098 O  O   . HOH   T 6 .   ? -1.656  -71.412 -2.250  1.00 42.84  ? 457 HOH   L O   1 
HETATM 7099 O  O   . HOH   T 6 .   ? 38.999  -39.098 -3.310  1.00 40.57  ? 458 HOH   L O   1 
HETATM 7100 O  O   . HOH   T 6 .   ? 7.009   -43.316 9.289   1.00 39.62  ? 459 HOH   L O   1 
HETATM 7101 O  O   . HOH   T 6 .   ? 16.153  -41.449 2.130   1.00 35.07  ? 460 HOH   L O   1 
HETATM 7102 O  O   . HOH   T 6 .   ? 11.719  -35.226 -2.635  1.00 38.71  ? 461 HOH   L O   1 
HETATM 7103 O  O   . HOH   T 6 .   ? 5.244   -58.701 20.002  1.00 42.89  ? 462 HOH   L O   1 
HETATM 7104 O  O   . HOH   T 6 .   ? 31.129  -28.814 -2.325  1.00 49.70  ? 463 HOH   L O   1 
HETATM 7105 O  O   . HOH   T 6 .   ? 30.573  -39.451 17.797  1.00 43.75  ? 464 HOH   L O   1 
HETATM 7106 O  O   . HOH   T 6 .   ? 34.929  -43.543 20.839  1.00 47.60  ? 465 HOH   L O   1 
HETATM 7107 O  O   . HOH   T 6 .   ? 32.637  -27.520 3.342   1.00 42.06  ? 466 HOH   L O   1 
HETATM 7108 O  O   . HOH   T 6 .   ? 9.531   -29.671 14.394  1.00 39.73  ? 467 HOH   L O   1 
HETATM 7109 O  O   . HOH   T 6 .   ? -0.359  -42.377 6.122   1.00 43.92  ? 468 HOH   L O   1 
HETATM 7110 O  O   . HOH   T 6 .   ? 16.121  -47.010 -14.861 1.00 44.87  ? 469 HOH   L O   1 
HETATM 7111 O  O   . HOH   T 6 .   ? 31.839  -54.664 5.201   1.00 38.07  ? 470 HOH   L O   1 
HETATM 7112 O  O   . HOH   T 6 .   ? 5.665   -35.871 7.408   1.00 37.29  ? 471 HOH   L O   1 
HETATM 7113 O  O   . HOH   T 6 .   ? 4.064   -52.125 -6.224  1.00 44.45  ? 472 HOH   L O   1 
HETATM 7114 O  O   . HOH   T 6 .   ? 10.318  -41.753 0.302   1.00 32.00  ? 473 HOH   L O   1 
HETATM 7115 O  O   . HOH   T 6 .   ? 10.670  -39.042 0.495   1.00 34.28  ? 474 HOH   L O   1 
HETATM 7116 O  O   . HOH   T 6 .   ? 38.271  -45.512 -5.939  1.00 44.97  ? 475 HOH   L O   1 
HETATM 7117 O  O   . HOH   T 6 .   ? 21.411  -45.723 0.056   1.00 35.49  ? 476 HOH   L O   1 
HETATM 7118 O  O   . HOH   T 6 .   ? 0.902   -68.577 -5.269  1.00 54.96  ? 477 HOH   L O   1 
HETATM 7119 O  O   . HOH   T 6 .   ? 2.078   -30.302 9.619   1.00 37.60  ? 478 HOH   L O   1 
HETATM 7120 O  O   . HOH   T 6 .   ? 38.147  -53.487 7.178   1.00 40.65  ? 479 HOH   L O   1 
HETATM 7121 O  O   . HOH   T 6 .   ? 21.556  -48.893 8.026   1.00 36.90  ? 480 HOH   L O   1 
HETATM 7122 O  O   . HOH   T 6 .   ? 5.592   -49.179 12.584  1.00 50.92  ? 481 HOH   L O   1 
HETATM 7123 O  O   . HOH   T 6 .   ? 35.263  -55.576 9.025   1.00 39.44  ? 482 HOH   L O   1 
HETATM 7124 O  O   . HOH   T 6 .   ? 27.475  -32.872 -3.901  1.00 52.09  ? 483 HOH   L O   1 
HETATM 7125 O  O   . HOH   T 6 .   ? 27.287  -51.834 16.620  1.00 40.56  ? 484 HOH   L O   1 
HETATM 7126 O  O   . HOH   T 6 .   ? 16.032  -44.547 -14.609 1.00 42.84  ? 485 HOH   L O   1 
HETATM 7127 O  O   . HOH   T 6 .   ? 9.003   -50.217 19.999  1.00 42.90  ? 486 HOH   L O   1 
HETATM 7128 O  O   . HOH   T 6 .   ? 11.569  -58.614 23.171  1.00 65.50  ? 487 HOH   L O   1 
HETATM 7129 O  O   . HOH   T 6 .   ? 28.323  -42.111 -12.533 1.00 40.67  ? 488 HOH   L O   1 
HETATM 7130 O  O   . HOH   T 6 .   ? -9.884  -67.720 -0.726  1.00 53.85  ? 489 HOH   L O   1 
HETATM 7131 O  O   . HOH   T 6 .   ? 29.588  -64.133 15.011  1.00 42.98  ? 490 HOH   L O   1 
HETATM 7132 O  O   . HOH   T 6 .   ? 15.410  -38.416 8.672   1.00 31.09  ? 491 HOH   L O   1 
HETATM 7133 O  O   . HOH   T 6 .   ? 20.533  -50.254 4.215   1.00 48.49  ? 492 HOH   L O   1 
HETATM 7134 O  O   . HOH   T 6 .   ? 38.934  -37.561 11.895  1.00 55.94  ? 493 HOH   L O   1 
HETATM 7135 O  O   . HOH   T 6 .   ? 10.021  -25.435 7.249   1.00 49.11  ? 494 HOH   L O   1 
HETATM 7136 O  O   . HOH   T 6 .   ? 30.753  -30.227 13.963  1.00 44.11  ? 495 HOH   L O   1 
HETATM 7137 O  O   . HOH   T 6 .   ? 25.717  -30.895 -6.783  1.00 64.93  ? 496 HOH   L O   1 
HETATM 7138 O  O   . HOH   T 6 .   ? -0.142  -63.338 -1.129  1.00 46.34  ? 497 HOH   L O   1 
HETATM 7139 O  O   . HOH   T 6 .   ? 15.610  -63.825 -1.186  1.00 41.90  ? 498 HOH   L O   1 
HETATM 7140 O  O   . HOH   T 6 .   ? 7.883   -33.322 3.551   1.00 36.83  ? 499 HOH   L O   1 
HETATM 7141 O  O   . HOH   T 6 .   ? 15.545  -55.357 -7.791  1.00 41.30  ? 500 HOH   L O   1 
HETATM 7142 O  O   . HOH   T 6 .   ? 0.413   -38.386 15.393  1.00 54.73  ? 501 HOH   L O   1 
HETATM 7143 O  O   . HOH   T 6 .   ? 3.829   -41.197 15.706  1.00 45.22  ? 502 HOH   L O   1 
HETATM 7144 O  O   . HOH   T 6 .   ? 40.045  -42.187 18.616  1.00 54.88  ? 503 HOH   L O   1 
HETATM 7145 O  O   . HOH   T 6 .   ? 4.304   -36.012 9.754   1.00 46.25  ? 504 HOH   L O   1 
HETATM 7146 O  O   . HOH   T 6 .   ? 11.514  -31.223 0.527   1.00 45.52  ? 505 HOH   L O   1 
HETATM 7147 O  O   . HOH   T 6 .   ? 48.134  -46.819 12.912  1.00 43.62  ? 506 HOH   L O   1 
HETATM 7148 O  O   . HOH   T 6 .   ? 22.066  -32.530 -6.053  1.00 43.70  ? 507 HOH   L O   1 
HETATM 7149 O  O   . HOH   T 6 .   ? 3.750   -27.028 5.486   1.00 43.77  ? 508 HOH   L O   1 
HETATM 7150 O  O   . HOH   T 6 .   ? 41.438  -39.034 -4.971  1.00 44.87  ? 509 HOH   L O   1 
HETATM 7151 O  O   . HOH   T 6 .   ? 22.355  -60.958 15.501  1.00 47.73  ? 510 HOH   L O   1 
HETATM 7152 O  O   . HOH   T 6 .   ? 2.621   -33.972 10.043  1.00 39.57  ? 511 HOH   L O   1 
HETATM 7153 O  O   . HOH   T 6 .   ? 38.186  -60.171 2.824   1.00 49.74  ? 512 HOH   L O   1 
HETATM 7154 O  O   . HOH   T 6 .   ? 2.796   -39.502 14.435  1.00 44.92  ? 513 HOH   L O   1 
HETATM 7155 O  O   . HOH   T 6 .   ? 34.113  -60.767 1.128   1.00 61.31  ? 514 HOH   L O   1 
# 
