data_9AZV
# 
_entry.id   9AZV 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9AZV         pdb_00009azv 10.2210/pdb9azv/pdb 
WWPDB D_1000282347 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-03-12 ? 
2 'Structure model' 1 1 2025-03-19 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
_pdbx_audit_revision_category.ordinal             1 
_pdbx_audit_revision_category.revision_ordinal    2 
_pdbx_audit_revision_category.data_content_type   'Structure model' 
_pdbx_audit_revision_category.category            citation 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.journal_volume' 
2 2 'Structure model' '_citation.page_first'     
3 2 'Structure model' '_citation.page_last'      
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9AZV 
_pdbx_database_status.recvd_initial_deposition_date   2024-03-11 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              aschmidt@crystal.harvard.edu 
_pdbx_contact_author.name_first         Aaron 
_pdbx_contact_author.name_last          Schmidt 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-3627-2553 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Maurer, D.P.'  1 ? 
'Schmidt, A.G.' 2 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Immunity 
_citation.journal_id_ASTM           IUNIEH 
_citation.journal_id_CSD            2048 
_citation.journal_id_ISSN           1074-7613 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            58 
_citation.language                  ? 
_citation.page_first                716 
_citation.page_last                 727.e6 
_citation.title                     'Antigenic drift expands influenza viral escape pathways from recalled humoral immunity.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.immuni.2025.02.006 
_citation.pdbx_database_id_PubMed   40023162 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Maurer, D.P.'  1 ? 
primary 'Vu, M.'        2 ? 
primary 'Schmidt, A.G.' 3 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'CH67 Fab heavy chain'                   26988.180 1 ? ?     ?             ? 
2 polymer     man 'CH67 Fab light chain'                   22828.133 1 ? ?     ?             ? 
3 polymer     man 'Hemagglutinin HA1 chain'                25462.266 1 ? G189E 'head domain' ? 
4 non-polymer man 2-acetamido-2-deoxy-beta-D-glucopyranose 221.208   1 ? ?     ?             ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;QVQLVQSGAEVRKPGASVKVSCKASGYTFTDNYIHWVRQAPGQGLEWMGWIHPNSGATKYAQKFEGWVTMTRDTSISTVY
MELSRSRSDDTAVYYCARAGLEPRSVDYYFYGLDVWGQGTAVTVSGASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFP
EPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKGSSLEVLFQ
GPLGHHHHHH
;
;QVQLVQSGAEVRKPGASVKVSCKASGYTFTDNYIHWVRQAPGQGLEWMGWIHPNSGATKYAQKFEGWVTMTRDTSISTVY
MELSRSRSDDTAVYYCARAGLEPRSVDYYFYGLDVWGQGTAVTVSGASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFP
EPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKGSSLEVLFQ
GPLGHHHHHH
;
H ? 
2 'polypeptide(L)' no no 
;QSVLTQPPSVSVAPGQTATITCGGNNIGRKRVDWFQQKPGQAPVLVVYEDSDRPSGIPERFSDSNSGTTATLTISRVEAG
DEADYYCQVWDSDSDHVVFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAG
VETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS
;
;QSVLTQPPSVSVAPGQTATITCGGNNIGRKRVDWFQQKPGQAPVLVVYEDSDRPSGIPERFSDSNSGTTATLTISRVEAG
DEADYYCQVWDSDSDHVVFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAG
VETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS
;
L ? 
3 'polypeptide(L)' no no 
;APLQLGNCSIAGWILGNPECESLFSKESWSYIAETPNSENGTCYPGYFADYEELREQLSSVSSFERFEIFPKESSWPNHT
VTKGVTASCSHNGKSSFYRNLLWLTEKNGLYPNLSKSYVNNKEKEVLVLWGVHHPSNIEDQRAIYHTENAYVSVVSSHYS
RRFTPEIAKRPKVRDQEGRINYYWTLLEPGDTIIFEANGNLIAPWYAFALSRGGAGSSLEVLFQ
;
;APLQLGNCSIAGWILGNPECESLFSKESWSYIAETPNSENGTCYPGYFADYEELREQLSSVSSFERFEIFPKESSWPNHT
VTKGVTASCSHNGKSSFYRNLLWLTEKNGLYPNLSKSYVNNKEKEVLVLWGVHHPSNIEDQRAIYHTENAYVSVVSSHYS
RRFTPEIAKRPKVRDQEGRINYYWTLLEPGDTIIFEANGNLIAPWYAFALSRGGAGSSLEVLFQ
;
E ? 
# 
_pdbx_entity_nonpoly.entity_id   4 
_pdbx_entity_nonpoly.name        2-acetamido-2-deoxy-beta-D-glucopyranose 
_pdbx_entity_nonpoly.comp_id     NAG 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLN n 
1 2   VAL n 
1 3   GLN n 
1 4   LEU n 
1 5   VAL n 
1 6   GLN n 
1 7   SER n 
1 8   GLY n 
1 9   ALA n 
1 10  GLU n 
1 11  VAL n 
1 12  ARG n 
1 13  LYS n 
1 14  PRO n 
1 15  GLY n 
1 16  ALA n 
1 17  SER n 
1 18  VAL n 
1 19  LYS n 
1 20  VAL n 
1 21  SER n 
1 22  CYS n 
1 23  LYS n 
1 24  ALA n 
1 25  SER n 
1 26  GLY n 
1 27  TYR n 
1 28  THR n 
1 29  PHE n 
1 30  THR n 
1 31  ASP n 
1 32  ASN n 
1 33  TYR n 
1 34  ILE n 
1 35  HIS n 
1 36  TRP n 
1 37  VAL n 
1 38  ARG n 
1 39  GLN n 
1 40  ALA n 
1 41  PRO n 
1 42  GLY n 
1 43  GLN n 
1 44  GLY n 
1 45  LEU n 
1 46  GLU n 
1 47  TRP n 
1 48  MET n 
1 49  GLY n 
1 50  TRP n 
1 51  ILE n 
1 52  HIS n 
1 53  PRO n 
1 54  ASN n 
1 55  SER n 
1 56  GLY n 
1 57  ALA n 
1 58  THR n 
1 59  LYS n 
1 60  TYR n 
1 61  ALA n 
1 62  GLN n 
1 63  LYS n 
1 64  PHE n 
1 65  GLU n 
1 66  GLY n 
1 67  TRP n 
1 68  VAL n 
1 69  THR n 
1 70  MET n 
1 71  THR n 
1 72  ARG n 
1 73  ASP n 
1 74  THR n 
1 75  SER n 
1 76  ILE n 
1 77  SER n 
1 78  THR n 
1 79  VAL n 
1 80  TYR n 
1 81  MET n 
1 82  GLU n 
1 83  LEU n 
1 84  SER n 
1 85  ARG n 
1 86  SER n 
1 87  ARG n 
1 88  SER n 
1 89  ASP n 
1 90  ASP n 
1 91  THR n 
1 92  ALA n 
1 93  VAL n 
1 94  TYR n 
1 95  TYR n 
1 96  CYS n 
1 97  ALA n 
1 98  ARG n 
1 99  ALA n 
1 100 GLY n 
1 101 LEU n 
1 102 GLU n 
1 103 PRO n 
1 104 ARG n 
1 105 SER n 
1 106 VAL n 
1 107 ASP n 
1 108 TYR n 
1 109 TYR n 
1 110 PHE n 
1 111 TYR n 
1 112 GLY n 
1 113 LEU n 
1 114 ASP n 
1 115 VAL n 
1 116 TRP n 
1 117 GLY n 
1 118 GLN n 
1 119 GLY n 
1 120 THR n 
1 121 ALA n 
1 122 VAL n 
1 123 THR n 
1 124 VAL n 
1 125 SER n 
1 126 GLY n 
1 127 ALA n 
1 128 SER n 
1 129 THR n 
1 130 LYS n 
1 131 GLY n 
1 132 PRO n 
1 133 SER n 
1 134 VAL n 
1 135 PHE n 
1 136 PRO n 
1 137 LEU n 
1 138 ALA n 
1 139 PRO n 
1 140 SER n 
1 141 SER n 
1 142 LYS n 
1 143 SER n 
1 144 THR n 
1 145 SER n 
1 146 GLY n 
1 147 GLY n 
1 148 THR n 
1 149 ALA n 
1 150 ALA n 
1 151 LEU n 
1 152 GLY n 
1 153 CYS n 
1 154 LEU n 
1 155 VAL n 
1 156 LYS n 
1 157 ASP n 
1 158 TYR n 
1 159 PHE n 
1 160 PRO n 
1 161 GLU n 
1 162 PRO n 
1 163 VAL n 
1 164 THR n 
1 165 VAL n 
1 166 SER n 
1 167 TRP n 
1 168 ASN n 
1 169 SER n 
1 170 GLY n 
1 171 ALA n 
1 172 LEU n 
1 173 THR n 
1 174 SER n 
1 175 GLY n 
1 176 VAL n 
1 177 HIS n 
1 178 THR n 
1 179 PHE n 
1 180 PRO n 
1 181 ALA n 
1 182 VAL n 
1 183 LEU n 
1 184 GLN n 
1 185 SER n 
1 186 SER n 
1 187 GLY n 
1 188 LEU n 
1 189 TYR n 
1 190 SER n 
1 191 LEU n 
1 192 SER n 
1 193 SER n 
1 194 VAL n 
1 195 VAL n 
1 196 THR n 
1 197 VAL n 
1 198 PRO n 
1 199 SER n 
1 200 SER n 
1 201 SER n 
1 202 LEU n 
1 203 GLY n 
1 204 THR n 
1 205 GLN n 
1 206 THR n 
1 207 TYR n 
1 208 ILE n 
1 209 CYS n 
1 210 ASN n 
1 211 VAL n 
1 212 ASN n 
1 213 HIS n 
1 214 LYS n 
1 215 PRO n 
1 216 SER n 
1 217 ASN n 
1 218 THR n 
1 219 LYS n 
1 220 VAL n 
1 221 ASP n 
1 222 LYS n 
1 223 ARG n 
1 224 VAL n 
1 225 GLU n 
1 226 PRO n 
1 227 LYS n 
1 228 SER n 
1 229 CYS n 
1 230 ASP n 
1 231 LYS n 
1 232 GLY n 
1 233 SER n 
1 234 SER n 
1 235 LEU n 
1 236 GLU n 
1 237 VAL n 
1 238 LEU n 
1 239 PHE n 
1 240 GLN n 
1 241 GLY n 
1 242 PRO n 
1 243 LEU n 
1 244 GLY n 
1 245 HIS n 
1 246 HIS n 
1 247 HIS n 
1 248 HIS n 
1 249 HIS n 
1 250 HIS n 
2 1   GLN n 
2 2   SER n 
2 3   VAL n 
2 4   LEU n 
2 5   THR n 
2 6   GLN n 
2 7   PRO n 
2 8   PRO n 
2 9   SER n 
2 10  VAL n 
2 11  SER n 
2 12  VAL n 
2 13  ALA n 
2 14  PRO n 
2 15  GLY n 
2 16  GLN n 
2 17  THR n 
2 18  ALA n 
2 19  THR n 
2 20  ILE n 
2 21  THR n 
2 22  CYS n 
2 23  GLY n 
2 24  GLY n 
2 25  ASN n 
2 26  ASN n 
2 27  ILE n 
2 28  GLY n 
2 29  ARG n 
2 30  LYS n 
2 31  ARG n 
2 32  VAL n 
2 33  ASP n 
2 34  TRP n 
2 35  PHE n 
2 36  GLN n 
2 37  GLN n 
2 38  LYS n 
2 39  PRO n 
2 40  GLY n 
2 41  GLN n 
2 42  ALA n 
2 43  PRO n 
2 44  VAL n 
2 45  LEU n 
2 46  VAL n 
2 47  VAL n 
2 48  TYR n 
2 49  GLU n 
2 50  ASP n 
2 51  SER n 
2 52  ASP n 
2 53  ARG n 
2 54  PRO n 
2 55  SER n 
2 56  GLY n 
2 57  ILE n 
2 58  PRO n 
2 59  GLU n 
2 60  ARG n 
2 61  PHE n 
2 62  SER n 
2 63  ASP n 
2 64  SER n 
2 65  ASN n 
2 66  SER n 
2 67  GLY n 
2 68  THR n 
2 69  THR n 
2 70  ALA n 
2 71  THR n 
2 72  LEU n 
2 73  THR n 
2 74  ILE n 
2 75  SER n 
2 76  ARG n 
2 77  VAL n 
2 78  GLU n 
2 79  ALA n 
2 80  GLY n 
2 81  ASP n 
2 82  GLU n 
2 83  ALA n 
2 84  ASP n 
2 85  TYR n 
2 86  TYR n 
2 87  CYS n 
2 88  GLN n 
2 89  VAL n 
2 90  TRP n 
2 91  ASP n 
2 92  SER n 
2 93  ASP n 
2 94  SER n 
2 95  ASP n 
2 96  HIS n 
2 97  VAL n 
2 98  VAL n 
2 99  PHE n 
2 100 GLY n 
2 101 GLY n 
2 102 GLY n 
2 103 THR n 
2 104 LYS n 
2 105 LEU n 
2 106 THR n 
2 107 VAL n 
2 108 LEU n 
2 109 GLY n 
2 110 GLN n 
2 111 PRO n 
2 112 LYS n 
2 113 ALA n 
2 114 ALA n 
2 115 PRO n 
2 116 SER n 
2 117 VAL n 
2 118 THR n 
2 119 LEU n 
2 120 PHE n 
2 121 PRO n 
2 122 PRO n 
2 123 SER n 
2 124 SER n 
2 125 GLU n 
2 126 GLU n 
2 127 LEU n 
2 128 GLN n 
2 129 ALA n 
2 130 ASN n 
2 131 LYS n 
2 132 ALA n 
2 133 THR n 
2 134 LEU n 
2 135 VAL n 
2 136 CYS n 
2 137 LEU n 
2 138 ILE n 
2 139 SER n 
2 140 ASP n 
2 141 PHE n 
2 142 TYR n 
2 143 PRO n 
2 144 GLY n 
2 145 ALA n 
2 146 VAL n 
2 147 THR n 
2 148 VAL n 
2 149 ALA n 
2 150 TRP n 
2 151 LYS n 
2 152 ALA n 
2 153 ASP n 
2 154 SER n 
2 155 SER n 
2 156 PRO n 
2 157 VAL n 
2 158 LYS n 
2 159 ALA n 
2 160 GLY n 
2 161 VAL n 
2 162 GLU n 
2 163 THR n 
2 164 THR n 
2 165 THR n 
2 166 PRO n 
2 167 SER n 
2 168 LYS n 
2 169 GLN n 
2 170 SER n 
2 171 ASN n 
2 172 ASN n 
2 173 LYS n 
2 174 TYR n 
2 175 ALA n 
2 176 ALA n 
2 177 SER n 
2 178 SER n 
2 179 TYR n 
2 180 LEU n 
2 181 SER n 
2 182 LEU n 
2 183 THR n 
2 184 PRO n 
2 185 GLU n 
2 186 GLN n 
2 187 TRP n 
2 188 LYS n 
2 189 SER n 
2 190 HIS n 
2 191 ARG n 
2 192 SER n 
2 193 TYR n 
2 194 SER n 
2 195 CYS n 
2 196 GLN n 
2 197 VAL n 
2 198 THR n 
2 199 HIS n 
2 200 GLU n 
2 201 GLY n 
2 202 SER n 
2 203 THR n 
2 204 VAL n 
2 205 GLU n 
2 206 LYS n 
2 207 THR n 
2 208 VAL n 
2 209 ALA n 
2 210 PRO n 
2 211 THR n 
2 212 GLU n 
2 213 CYS n 
2 214 SER n 
3 1   ALA n 
3 2   PRO n 
3 3   LEU n 
3 4   GLN n 
3 5   LEU n 
3 6   GLY n 
3 7   ASN n 
3 8   CYS n 
3 9   SER n 
3 10  ILE n 
3 11  ALA n 
3 12  GLY n 
3 13  TRP n 
3 14  ILE n 
3 15  LEU n 
3 16  GLY n 
3 17  ASN n 
3 18  PRO n 
3 19  GLU n 
3 20  CYS n 
3 21  GLU n 
3 22  SER n 
3 23  LEU n 
3 24  PHE n 
3 25  SER n 
3 26  LYS n 
3 27  GLU n 
3 28  SER n 
3 29  TRP n 
3 30  SER n 
3 31  TYR n 
3 32  ILE n 
3 33  ALA n 
3 34  GLU n 
3 35  THR n 
3 36  PRO n 
3 37  ASN n 
3 38  SER n 
3 39  GLU n 
3 40  ASN n 
3 41  GLY n 
3 42  THR n 
3 43  CYS n 
3 44  TYR n 
3 45  PRO n 
3 46  GLY n 
3 47  TYR n 
3 48  PHE n 
3 49  ALA n 
3 50  ASP n 
3 51  TYR n 
3 52  GLU n 
3 53  GLU n 
3 54  LEU n 
3 55  ARG n 
3 56  GLU n 
3 57  GLN n 
3 58  LEU n 
3 59  SER n 
3 60  SER n 
3 61  VAL n 
3 62  SER n 
3 63  SER n 
3 64  PHE n 
3 65  GLU n 
3 66  ARG n 
3 67  PHE n 
3 68  GLU n 
3 69  ILE n 
3 70  PHE n 
3 71  PRO n 
3 72  LYS n 
3 73  GLU n 
3 74  SER n 
3 75  SER n 
3 76  TRP n 
3 77  PRO n 
3 78  ASN n 
3 79  HIS n 
3 80  THR n 
3 81  VAL n 
3 82  THR n 
3 83  LYS n 
3 84  GLY n 
3 85  VAL n 
3 86  THR n 
3 87  ALA n 
3 88  SER n 
3 89  CYS n 
3 90  SER n 
3 91  HIS n 
3 92  ASN n 
3 93  GLY n 
3 94  LYS n 
3 95  SER n 
3 96  SER n 
3 97  PHE n 
3 98  TYR n 
3 99  ARG n 
3 100 ASN n 
3 101 LEU n 
3 102 LEU n 
3 103 TRP n 
3 104 LEU n 
3 105 THR n 
3 106 GLU n 
3 107 LYS n 
3 108 ASN n 
3 109 GLY n 
3 110 LEU n 
3 111 TYR n 
3 112 PRO n 
3 113 ASN n 
3 114 LEU n 
3 115 SER n 
3 116 LYS n 
3 117 SER n 
3 118 TYR n 
3 119 VAL n 
3 120 ASN n 
3 121 ASN n 
3 122 LYS n 
3 123 GLU n 
3 124 LYS n 
3 125 GLU n 
3 126 VAL n 
3 127 LEU n 
3 128 VAL n 
3 129 LEU n 
3 130 TRP n 
3 131 GLY n 
3 132 VAL n 
3 133 HIS n 
3 134 HIS n 
3 135 PRO n 
3 136 SER n 
3 137 ASN n 
3 138 ILE n 
3 139 GLU n 
3 140 ASP n 
3 141 GLN n 
3 142 ARG n 
3 143 ALA n 
3 144 ILE n 
3 145 TYR n 
3 146 HIS n 
3 147 THR n 
3 148 GLU n 
3 149 ASN n 
3 150 ALA n 
3 151 TYR n 
3 152 VAL n 
3 153 SER n 
3 154 VAL n 
3 155 VAL n 
3 156 SER n 
3 157 SER n 
3 158 HIS n 
3 159 TYR n 
3 160 SER n 
3 161 ARG n 
3 162 ARG n 
3 163 PHE n 
3 164 THR n 
3 165 PRO n 
3 166 GLU n 
3 167 ILE n 
3 168 ALA n 
3 169 LYS n 
3 170 ARG n 
3 171 PRO n 
3 172 LYS n 
3 173 VAL n 
3 174 ARG n 
3 175 ASP n 
3 176 GLN n 
3 177 GLU n 
3 178 GLY n 
3 179 ARG n 
3 180 ILE n 
3 181 ASN n 
3 182 TYR n 
3 183 TYR n 
3 184 TRP n 
3 185 THR n 
3 186 LEU n 
3 187 LEU n 
3 188 GLU n 
3 189 PRO n 
3 190 GLY n 
3 191 ASP n 
3 192 THR n 
3 193 ILE n 
3 194 ILE n 
3 195 PHE n 
3 196 GLU n 
3 197 ALA n 
3 198 ASN n 
3 199 GLY n 
3 200 ASN n 
3 201 LEU n 
3 202 ILE n 
3 203 ALA n 
3 204 PRO n 
3 205 TRP n 
3 206 TYR n 
3 207 ALA n 
3 208 PHE n 
3 209 ALA n 
3 210 LEU n 
3 211 SER n 
3 212 ARG n 
3 213 GLY n 
3 214 GLY n 
3 215 ALA n 
3 216 GLY n 
3 217 SER n 
3 218 SER n 
3 219 LEU n 
3 220 GLU n 
3 221 VAL n 
3 222 LEU n 
3 223 PHE n 
3 224 GLN n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 250 ? ? ?  ? ?                              ? ? ? ? 'Homo sapiens'      9606   ? ? ? ? ? ? ? ? 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 214 ? ? ?  ? ?                              ? ? ? ? 'Homo sapiens'      9606   ? ? ? ? ? ? ? ? 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 224 ? ? HA ? 'A/Massachusetts/1/1990(H1N1)' ? ? ? ? 'Influenza A virus' 387165 ? ? ? ? ? ? ? ? 
'Homo sapiens' 9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'          y ALANINE                                  ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'          y ARGININE                                 ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'          y ASPARAGINE                               ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'          y 'ASPARTIC ACID'                          ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking'          y CYSTEINE                                 ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking'          y GLUTAMINE                                ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'          y 'GLUTAMIC ACID'                          ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'            y GLYCINE                                  ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'          y HISTIDINE                                ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking'          y ISOLEUCINE                               ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'          y LEUCINE                                  ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'          y LYSINE                                   ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking'          y METHIONINE                               ? 'C5 H11 N O2 S'  149.211 
NAG 'D-saccharide, beta linking' . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'    221.208 
PHE 'L-peptide linking'          y PHENYLALANINE                            ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'          y PROLINE                                  ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'          y SERINE                                   ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking'          y THREONINE                                ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'          y TRYPTOPHAN                               ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'          y TYROSINE                                 ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'          y VALINE                                   ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLN 1   1   1   GLN GLN H . n 
A 1 2   VAL 2   2   2   VAL VAL H . n 
A 1 3   GLN 3   3   3   GLN GLN H . n 
A 1 4   LEU 4   4   4   LEU LEU H . n 
A 1 5   VAL 5   5   5   VAL VAL H . n 
A 1 6   GLN 6   6   6   GLN GLN H . n 
A 1 7   SER 7   7   7   SER SER H . n 
A 1 8   GLY 8   8   8   GLY GLY H . n 
A 1 9   ALA 9   9   9   ALA ALA H . n 
A 1 10  GLU 10  10  10  GLU GLU H . n 
A 1 11  VAL 11  11  11  VAL VAL H . n 
A 1 12  ARG 12  12  12  ARG ARG H . n 
A 1 13  LYS 13  13  13  LYS LYS H . n 
A 1 14  PRO 14  14  14  PRO PRO H . n 
A 1 15  GLY 15  15  15  GLY GLY H . n 
A 1 16  ALA 16  16  16  ALA ALA H . n 
A 1 17  SER 17  17  17  SER SER H . n 
A 1 18  VAL 18  18  18  VAL VAL H . n 
A 1 19  LYS 19  19  19  LYS LYS H . n 
A 1 20  VAL 20  20  20  VAL VAL H . n 
A 1 21  SER 21  21  21  SER SER H . n 
A 1 22  CYS 22  22  22  CYS CYS H . n 
A 1 23  LYS 23  23  23  LYS LYS H . n 
A 1 24  ALA 24  24  24  ALA ALA H . n 
A 1 25  SER 25  25  25  SER SER H . n 
A 1 26  GLY 26  26  26  GLY GLY H . n 
A 1 27  TYR 27  27  27  TYR TYR H . n 
A 1 28  THR 28  28  28  THR THR H . n 
A 1 29  PHE 29  29  29  PHE PHE H . n 
A 1 30  THR 30  30  30  THR THR H . n 
A 1 31  ASP 31  31  31  ASP ASP H . n 
A 1 32  ASN 32  32  32  ASN ASN H . n 
A 1 33  TYR 33  33  33  TYR TYR H . n 
A 1 34  ILE 34  34  34  ILE ILE H . n 
A 1 35  HIS 35  35  35  HIS HIS H . n 
A 1 36  TRP 36  36  36  TRP TRP H . n 
A 1 37  VAL 37  37  37  VAL VAL H . n 
A 1 38  ARG 38  38  38  ARG ARG H . n 
A 1 39  GLN 39  39  39  GLN GLN H . n 
A 1 40  ALA 40  40  40  ALA ALA H . n 
A 1 41  PRO 41  41  41  PRO PRO H . n 
A 1 42  GLY 42  42  42  GLY GLY H . n 
A 1 43  GLN 43  43  43  GLN GLN H . n 
A 1 44  GLY 44  44  44  GLY GLY H . n 
A 1 45  LEU 45  45  45  LEU LEU H . n 
A 1 46  GLU 46  46  46  GLU GLU H . n 
A 1 47  TRP 47  47  47  TRP TRP H . n 
A 1 48  MET 48  48  48  MET MET H . n 
A 1 49  GLY 49  49  49  GLY GLY H . n 
A 1 50  TRP 50  50  50  TRP TRP H . n 
A 1 51  ILE 51  51  51  ILE ILE H . n 
A 1 52  HIS 52  52  52  HIS HIS H . n 
A 1 53  PRO 53  53  53  PRO PRO H . n 
A 1 54  ASN 54  54  54  ASN ASN H . n 
A 1 55  SER 55  55  55  SER SER H . n 
A 1 56  GLY 56  56  56  GLY GLY H . n 
A 1 57  ALA 57  57  57  ALA ALA H . n 
A 1 58  THR 58  58  58  THR THR H . n 
A 1 59  LYS 59  59  59  LYS LYS H . n 
A 1 60  TYR 60  60  60  TYR TYR H . n 
A 1 61  ALA 61  61  61  ALA ALA H . n 
A 1 62  GLN 62  62  62  GLN GLN H . n 
A 1 63  LYS 63  63  63  LYS LYS H . n 
A 1 64  PHE 64  64  64  PHE PHE H . n 
A 1 65  GLU 65  65  65  GLU GLU H . n 
A 1 66  GLY 66  66  66  GLY GLY H . n 
A 1 67  TRP 67  67  67  TRP TRP H . n 
A 1 68  VAL 68  68  68  VAL VAL H . n 
A 1 69  THR 69  69  69  THR THR H . n 
A 1 70  MET 70  70  70  MET MET H . n 
A 1 71  THR 71  71  71  THR THR H . n 
A 1 72  ARG 72  72  72  ARG ARG H . n 
A 1 73  ASP 73  73  73  ASP ASP H . n 
A 1 74  THR 74  74  74  THR THR H . n 
A 1 75  SER 75  75  75  SER SER H . n 
A 1 76  ILE 76  76  76  ILE ILE H . n 
A 1 77  SER 77  77  77  SER SER H . n 
A 1 78  THR 78  78  78  THR THR H . n 
A 1 79  VAL 79  79  79  VAL VAL H . n 
A 1 80  TYR 80  80  80  TYR TYR H . n 
A 1 81  MET 81  81  81  MET MET H . n 
A 1 82  GLU 82  82  82  GLU GLU H . n 
A 1 83  LEU 83  83  83  LEU LEU H . n 
A 1 84  SER 84  84  84  SER SER H . n 
A 1 85  ARG 85  85  85  ARG ARG H . n 
A 1 86  SER 86  86  86  SER SER H . n 
A 1 87  ARG 87  87  87  ARG ARG H . n 
A 1 88  SER 88  88  88  SER SER H . n 
A 1 89  ASP 89  89  89  ASP ASP H . n 
A 1 90  ASP 90  90  90  ASP ASP H . n 
A 1 91  THR 91  91  91  THR THR H . n 
A 1 92  ALA 92  92  92  ALA ALA H . n 
A 1 93  VAL 93  93  93  VAL VAL H . n 
A 1 94  TYR 94  94  94  TYR TYR H . n 
A 1 95  TYR 95  95  95  TYR TYR H . n 
A 1 96  CYS 96  96  96  CYS CYS H . n 
A 1 97  ALA 97  97  97  ALA ALA H . n 
A 1 98  ARG 98  98  98  ARG ARG H . n 
A 1 99  ALA 99  99  99  ALA ALA H . n 
A 1 100 GLY 100 100 100 GLY GLY H . n 
A 1 101 LEU 101 101 101 LEU LEU H . n 
A 1 102 GLU 102 102 102 GLU GLU H . n 
A 1 103 PRO 103 103 103 PRO PRO H . n 
A 1 104 ARG 104 104 104 ARG ARG H . n 
A 1 105 SER 105 105 105 SER SER H . n 
A 1 106 VAL 106 106 106 VAL VAL H . n 
A 1 107 ASP 107 107 107 ASP ASP H . n 
A 1 108 TYR 108 108 108 TYR TYR H . n 
A 1 109 TYR 109 109 109 TYR TYR H . n 
A 1 110 PHE 110 110 110 PHE PHE H . n 
A 1 111 TYR 111 111 111 TYR TYR H . n 
A 1 112 GLY 112 112 112 GLY GLY H . n 
A 1 113 LEU 113 113 113 LEU LEU H . n 
A 1 114 ASP 114 114 114 ASP ASP H . n 
A 1 115 VAL 115 115 115 VAL VAL H . n 
A 1 116 TRP 116 116 116 TRP TRP H . n 
A 1 117 GLY 117 117 117 GLY GLY H . n 
A 1 118 GLN 118 118 118 GLN GLN H . n 
A 1 119 GLY 119 119 119 GLY GLY H . n 
A 1 120 THR 120 120 120 THR THR H . n 
A 1 121 ALA 121 121 121 ALA ALA H . n 
A 1 122 VAL 122 122 122 VAL VAL H . n 
A 1 123 THR 123 123 123 THR THR H . n 
A 1 124 VAL 124 124 124 VAL VAL H . n 
A 1 125 SER 125 125 125 SER SER H . n 
A 1 126 GLY 126 126 126 GLY GLY H . n 
A 1 127 ALA 127 127 127 ALA ALA H . n 
A 1 128 SER 128 128 128 SER SER H . n 
A 1 129 THR 129 129 129 THR THR H . n 
A 1 130 LYS 130 130 130 LYS LYS H . n 
A 1 131 GLY 131 131 131 GLY GLY H . n 
A 1 132 PRO 132 132 132 PRO PRO H . n 
A 1 133 SER 133 133 133 SER SER H . n 
A 1 134 VAL 134 134 134 VAL VAL H . n 
A 1 135 PHE 135 135 135 PHE PHE H . n 
A 1 136 PRO 136 136 136 PRO PRO H . n 
A 1 137 LEU 137 137 137 LEU LEU H . n 
A 1 138 ALA 138 138 138 ALA ALA H . n 
A 1 139 PRO 139 139 139 PRO PRO H . n 
A 1 140 SER 140 140 140 SER SER H . n 
A 1 141 SER 141 141 141 SER SER H . n 
A 1 142 LYS 142 142 142 LYS LYS H . n 
A 1 143 SER 143 143 143 SER SER H . n 
A 1 144 THR 144 144 144 THR THR H . n 
A 1 145 SER 145 145 145 SER SER H . n 
A 1 146 GLY 146 146 146 GLY GLY H . n 
A 1 147 GLY 147 147 147 GLY GLY H . n 
A 1 148 THR 148 148 148 THR THR H . n 
A 1 149 ALA 149 149 149 ALA ALA H . n 
A 1 150 ALA 150 150 150 ALA ALA H . n 
A 1 151 LEU 151 151 151 LEU LEU H . n 
A 1 152 GLY 152 152 152 GLY GLY H . n 
A 1 153 CYS 153 153 153 CYS CYS H . n 
A 1 154 LEU 154 154 154 LEU LEU H . n 
A 1 155 VAL 155 155 155 VAL VAL H . n 
A 1 156 LYS 156 156 156 LYS LYS H . n 
A 1 157 ASP 157 157 157 ASP ASP H . n 
A 1 158 TYR 158 158 158 TYR TYR H . n 
A 1 159 PHE 159 159 159 PHE PHE H . n 
A 1 160 PRO 160 160 160 PRO PRO H . n 
A 1 161 GLU 161 161 161 GLU GLU H . n 
A 1 162 PRO 162 162 162 PRO PRO H . n 
A 1 163 VAL 163 163 163 VAL VAL H . n 
A 1 164 THR 164 164 164 THR THR H . n 
A 1 165 VAL 165 165 165 VAL VAL H . n 
A 1 166 SER 166 166 166 SER SER H . n 
A 1 167 TRP 167 167 167 TRP TRP H . n 
A 1 168 ASN 168 168 168 ASN ASN H . n 
A 1 169 SER 169 169 169 SER SER H . n 
A 1 170 GLY 170 170 170 GLY GLY H . n 
A 1 171 ALA 171 171 171 ALA ALA H . n 
A 1 172 LEU 172 172 172 LEU LEU H . n 
A 1 173 THR 173 173 173 THR THR H . n 
A 1 174 SER 174 174 174 SER SER H . n 
A 1 175 GLY 175 175 175 GLY GLY H . n 
A 1 176 VAL 176 176 176 VAL VAL H . n 
A 1 177 HIS 177 177 177 HIS HIS H . n 
A 1 178 THR 178 178 178 THR THR H . n 
A 1 179 PHE 179 179 179 PHE PHE H . n 
A 1 180 PRO 180 180 180 PRO PRO H . n 
A 1 181 ALA 181 181 181 ALA ALA H . n 
A 1 182 VAL 182 182 182 VAL VAL H . n 
A 1 183 LEU 183 183 183 LEU LEU H . n 
A 1 184 GLN 184 184 184 GLN GLN H . n 
A 1 185 SER 185 185 185 SER SER H . n 
A 1 186 SER 186 186 186 SER SER H . n 
A 1 187 GLY 187 187 187 GLY GLY H . n 
A 1 188 LEU 188 188 188 LEU LEU H . n 
A 1 189 TYR 189 189 189 TYR TYR H . n 
A 1 190 SER 190 190 190 SER SER H . n 
A 1 191 LEU 191 191 191 LEU LEU H . n 
A 1 192 SER 192 192 192 SER SER H . n 
A 1 193 SER 193 193 193 SER SER H . n 
A 1 194 VAL 194 194 194 VAL VAL H . n 
A 1 195 VAL 195 195 195 VAL VAL H . n 
A 1 196 THR 196 196 196 THR THR H . n 
A 1 197 VAL 197 197 197 VAL VAL H . n 
A 1 198 PRO 198 198 198 PRO PRO H . n 
A 1 199 SER 199 199 199 SER SER H . n 
A 1 200 SER 200 200 200 SER SER H . n 
A 1 201 SER 201 201 201 SER SER H . n 
A 1 202 LEU 202 202 202 LEU LEU H . n 
A 1 203 GLY 203 203 203 GLY GLY H . n 
A 1 204 THR 204 204 204 THR THR H . n 
A 1 205 GLN 205 205 205 GLN GLN H . n 
A 1 206 THR 206 206 206 THR THR H . n 
A 1 207 TYR 207 207 207 TYR TYR H . n 
A 1 208 ILE 208 208 208 ILE ILE H . n 
A 1 209 CYS 209 209 209 CYS CYS H . n 
A 1 210 ASN 210 210 210 ASN ASN H . n 
A 1 211 VAL 211 211 211 VAL VAL H . n 
A 1 212 ASN 212 212 212 ASN ASN H . n 
A 1 213 HIS 213 213 213 HIS HIS H . n 
A 1 214 LYS 214 214 214 LYS LYS H . n 
A 1 215 PRO 215 215 215 PRO PRO H . n 
A 1 216 SER 216 216 216 SER SER H . n 
A 1 217 ASN 217 217 217 ASN ASN H . n 
A 1 218 THR 218 218 218 THR THR H . n 
A 1 219 LYS 219 219 219 LYS LYS H . n 
A 1 220 VAL 220 220 220 VAL VAL H . n 
A 1 221 ASP 221 221 221 ASP ASP H . n 
A 1 222 LYS 222 222 222 LYS LYS H . n 
A 1 223 ARG 223 223 223 ARG ARG H . n 
A 1 224 VAL 224 224 224 VAL VAL H . n 
A 1 225 GLU 225 225 225 GLU GLU H . n 
A 1 226 PRO 226 226 226 PRO PRO H . n 
A 1 227 LYS 227 227 227 LYS LYS H . n 
A 1 228 SER 228 228 ?   ?   ?   H . n 
A 1 229 CYS 229 229 ?   ?   ?   H . n 
A 1 230 ASP 230 230 ?   ?   ?   H . n 
A 1 231 LYS 231 231 ?   ?   ?   H . n 
A 1 232 GLY 232 232 ?   ?   ?   H . n 
A 1 233 SER 233 233 ?   ?   ?   H . n 
A 1 234 SER 234 234 ?   ?   ?   H . n 
A 1 235 LEU 235 235 ?   ?   ?   H . n 
A 1 236 GLU 236 236 ?   ?   ?   H . n 
A 1 237 VAL 237 237 ?   ?   ?   H . n 
A 1 238 LEU 238 238 ?   ?   ?   H . n 
A 1 239 PHE 239 239 ?   ?   ?   H . n 
A 1 240 GLN 240 240 ?   ?   ?   H . n 
A 1 241 GLY 241 241 ?   ?   ?   H . n 
A 1 242 PRO 242 242 ?   ?   ?   H . n 
A 1 243 LEU 243 243 ?   ?   ?   H . n 
A 1 244 GLY 244 244 ?   ?   ?   H . n 
A 1 245 HIS 245 245 ?   ?   ?   H . n 
A 1 246 HIS 246 246 ?   ?   ?   H . n 
A 1 247 HIS 247 247 ?   ?   ?   H . n 
A 1 248 HIS 248 248 ?   ?   ?   H . n 
A 1 249 HIS 249 249 ?   ?   ?   H . n 
A 1 250 HIS 250 250 ?   ?   ?   H . n 
B 2 1   GLN 1   1   ?   ?   ?   L . n 
B 2 2   SER 2   2   2   SER SER L . n 
B 2 3   VAL 3   3   3   VAL VAL L . n 
B 2 4   LEU 4   4   4   LEU LEU L . n 
B 2 5   THR 5   5   5   THR THR L . n 
B 2 6   GLN 6   6   6   GLN GLN L . n 
B 2 7   PRO 7   7   7   PRO PRO L . n 
B 2 8   PRO 8   8   8   PRO PRO L . n 
B 2 9   SER 9   9   9   SER SER L . n 
B 2 10  VAL 10  10  10  VAL VAL L . n 
B 2 11  SER 11  11  11  SER SER L . n 
B 2 12  VAL 12  12  12  VAL VAL L . n 
B 2 13  ALA 13  13  13  ALA ALA L . n 
B 2 14  PRO 14  14  14  PRO PRO L . n 
B 2 15  GLY 15  15  15  GLY GLY L . n 
B 2 16  GLN 16  16  16  GLN GLN L . n 
B 2 17  THR 17  17  17  THR THR L . n 
B 2 18  ALA 18  18  18  ALA ALA L . n 
B 2 19  THR 19  19  19  THR THR L . n 
B 2 20  ILE 20  20  20  ILE ILE L . n 
B 2 21  THR 21  21  21  THR THR L . n 
B 2 22  CYS 22  22  22  CYS CYS L . n 
B 2 23  GLY 23  23  23  GLY GLY L . n 
B 2 24  GLY 24  24  24  GLY GLY L . n 
B 2 25  ASN 25  25  25  ASN ASN L . n 
B 2 26  ASN 26  26  26  ASN ASN L . n 
B 2 27  ILE 27  27  27  ILE ILE L . n 
B 2 28  GLY 28  28  28  GLY GLY L . n 
B 2 29  ARG 29  29  29  ARG ARG L . n 
B 2 30  LYS 30  30  30  LYS LYS L . n 
B 2 31  ARG 31  31  31  ARG ARG L . n 
B 2 32  VAL 32  32  32  VAL VAL L . n 
B 2 33  ASP 33  33  33  ASP ASP L . n 
B 2 34  TRP 34  34  34  TRP TRP L . n 
B 2 35  PHE 35  35  35  PHE PHE L . n 
B 2 36  GLN 36  36  36  GLN GLN L . n 
B 2 37  GLN 37  37  37  GLN GLN L . n 
B 2 38  LYS 38  38  38  LYS LYS L . n 
B 2 39  PRO 39  39  39  PRO PRO L . n 
B 2 40  GLY 40  40  40  GLY GLY L . n 
B 2 41  GLN 41  41  41  GLN GLN L . n 
B 2 42  ALA 42  42  42  ALA ALA L . n 
B 2 43  PRO 43  43  43  PRO PRO L . n 
B 2 44  VAL 44  44  44  VAL VAL L . n 
B 2 45  LEU 45  45  45  LEU LEU L . n 
B 2 46  VAL 46  46  46  VAL VAL L . n 
B 2 47  VAL 47  47  47  VAL VAL L . n 
B 2 48  TYR 48  48  48  TYR TYR L . n 
B 2 49  GLU 49  49  49  GLU GLU L . n 
B 2 50  ASP 50  50  50  ASP ASP L . n 
B 2 51  SER 51  51  51  SER SER L . n 
B 2 52  ASP 52  52  52  ASP ASP L . n 
B 2 53  ARG 53  53  53  ARG ARG L . n 
B 2 54  PRO 54  54  54  PRO PRO L . n 
B 2 55  SER 55  55  55  SER SER L . n 
B 2 56  GLY 56  56  56  GLY GLY L . n 
B 2 57  ILE 57  57  57  ILE ILE L . n 
B 2 58  PRO 58  58  58  PRO PRO L . n 
B 2 59  GLU 59  59  59  GLU GLU L . n 
B 2 60  ARG 60  60  60  ARG ARG L . n 
B 2 61  PHE 61  61  61  PHE PHE L . n 
B 2 62  SER 62  62  62  SER SER L . n 
B 2 63  ASP 63  63  63  ASP ASP L . n 
B 2 64  SER 64  64  64  SER SER L . n 
B 2 65  ASN 65  65  65  ASN ASN L . n 
B 2 66  SER 66  66  66  SER SER L . n 
B 2 67  GLY 67  67  67  GLY GLY L . n 
B 2 68  THR 68  68  68  THR THR L . n 
B 2 69  THR 69  69  69  THR THR L . n 
B 2 70  ALA 70  70  70  ALA ALA L . n 
B 2 71  THR 71  71  71  THR THR L . n 
B 2 72  LEU 72  72  72  LEU LEU L . n 
B 2 73  THR 73  73  73  THR THR L . n 
B 2 74  ILE 74  74  74  ILE ILE L . n 
B 2 75  SER 75  75  75  SER SER L . n 
B 2 76  ARG 76  76  76  ARG ARG L . n 
B 2 77  VAL 77  77  77  VAL VAL L . n 
B 2 78  GLU 78  78  78  GLU GLU L . n 
B 2 79  ALA 79  79  79  ALA ALA L . n 
B 2 80  GLY 80  80  80  GLY GLY L . n 
B 2 81  ASP 81  81  81  ASP ASP L . n 
B 2 82  GLU 82  82  82  GLU GLU L . n 
B 2 83  ALA 83  83  83  ALA ALA L . n 
B 2 84  ASP 84  84  84  ASP ASP L . n 
B 2 85  TYR 85  85  85  TYR TYR L . n 
B 2 86  TYR 86  86  86  TYR TYR L . n 
B 2 87  CYS 87  87  87  CYS CYS L . n 
B 2 88  GLN 88  88  88  GLN GLN L . n 
B 2 89  VAL 89  89  89  VAL VAL L . n 
B 2 90  TRP 90  90  90  TRP TRP L . n 
B 2 91  ASP 91  91  91  ASP ASP L . n 
B 2 92  SER 92  92  92  SER SER L . n 
B 2 93  ASP 93  93  93  ASP ASP L . n 
B 2 94  SER 94  94  94  SER SER L . n 
B 2 95  ASP 95  95  95  ASP ASP L . n 
B 2 96  HIS 96  96  96  HIS HIS L . n 
B 2 97  VAL 97  97  97  VAL VAL L . n 
B 2 98  VAL 98  98  98  VAL VAL L . n 
B 2 99  PHE 99  99  99  PHE PHE L . n 
B 2 100 GLY 100 100 100 GLY GLY L . n 
B 2 101 GLY 101 101 101 GLY GLY L . n 
B 2 102 GLY 102 102 102 GLY GLY L . n 
B 2 103 THR 103 103 103 THR THR L . n 
B 2 104 LYS 104 104 104 LYS LYS L . n 
B 2 105 LEU 105 105 105 LEU LEU L . n 
B 2 106 THR 106 106 106 THR THR L . n 
B 2 107 VAL 107 107 107 VAL VAL L . n 
B 2 108 LEU 108 108 108 LEU LEU L . n 
B 2 109 GLY 109 109 109 GLY GLY L . n 
B 2 110 GLN 110 110 110 GLN GLN L . n 
B 2 111 PRO 111 111 111 PRO PRO L . n 
B 2 112 LYS 112 112 112 LYS LYS L . n 
B 2 113 ALA 113 113 113 ALA ALA L . n 
B 2 114 ALA 114 114 114 ALA ALA L . n 
B 2 115 PRO 115 115 115 PRO PRO L . n 
B 2 116 SER 116 116 116 SER SER L . n 
B 2 117 VAL 117 117 117 VAL VAL L . n 
B 2 118 THR 118 118 118 THR THR L . n 
B 2 119 LEU 119 119 119 LEU LEU L . n 
B 2 120 PHE 120 120 120 PHE PHE L . n 
B 2 121 PRO 121 121 121 PRO PRO L . n 
B 2 122 PRO 122 122 122 PRO PRO L . n 
B 2 123 SER 123 123 123 SER SER L . n 
B 2 124 SER 124 124 124 SER SER L . n 
B 2 125 GLU 125 125 125 GLU GLU L . n 
B 2 126 GLU 126 126 126 GLU GLU L . n 
B 2 127 LEU 127 127 127 LEU LEU L . n 
B 2 128 GLN 128 128 128 GLN GLN L . n 
B 2 129 ALA 129 129 129 ALA ALA L . n 
B 2 130 ASN 130 130 130 ASN ASN L . n 
B 2 131 LYS 131 131 131 LYS LYS L . n 
B 2 132 ALA 132 132 132 ALA ALA L . n 
B 2 133 THR 133 133 133 THR THR L . n 
B 2 134 LEU 134 134 134 LEU LEU L . n 
B 2 135 VAL 135 135 135 VAL VAL L . n 
B 2 136 CYS 136 136 136 CYS CYS L . n 
B 2 137 LEU 137 137 137 LEU LEU L . n 
B 2 138 ILE 138 138 138 ILE ILE L . n 
B 2 139 SER 139 139 139 SER SER L . n 
B 2 140 ASP 140 140 140 ASP ASP L . n 
B 2 141 PHE 141 141 141 PHE PHE L . n 
B 2 142 TYR 142 142 142 TYR TYR L . n 
B 2 143 PRO 143 143 143 PRO PRO L . n 
B 2 144 GLY 144 144 144 GLY GLY L . n 
B 2 145 ALA 145 145 145 ALA ALA L . n 
B 2 146 VAL 146 146 146 VAL VAL L . n 
B 2 147 THR 147 147 147 THR THR L . n 
B 2 148 VAL 148 148 148 VAL VAL L . n 
B 2 149 ALA 149 149 149 ALA ALA L . n 
B 2 150 TRP 150 150 150 TRP TRP L . n 
B 2 151 LYS 151 151 151 LYS LYS L . n 
B 2 152 ALA 152 152 152 ALA ALA L . n 
B 2 153 ASP 153 153 153 ASP ASP L . n 
B 2 154 SER 154 154 154 SER SER L . n 
B 2 155 SER 155 155 155 SER SER L . n 
B 2 156 PRO 156 156 156 PRO PRO L . n 
B 2 157 VAL 157 157 157 VAL VAL L . n 
B 2 158 LYS 158 158 158 LYS LYS L . n 
B 2 159 ALA 159 159 159 ALA ALA L . n 
B 2 160 GLY 160 160 160 GLY GLY L . n 
B 2 161 VAL 161 161 161 VAL VAL L . n 
B 2 162 GLU 162 162 162 GLU GLU L . n 
B 2 163 THR 163 163 163 THR THR L . n 
B 2 164 THR 164 164 164 THR THR L . n 
B 2 165 THR 165 165 165 THR THR L . n 
B 2 166 PRO 166 166 166 PRO PRO L . n 
B 2 167 SER 167 167 167 SER SER L . n 
B 2 168 LYS 168 168 168 LYS LYS L . n 
B 2 169 GLN 169 169 169 GLN GLN L . n 
B 2 170 SER 170 170 170 SER SER L . n 
B 2 171 ASN 171 171 171 ASN ASN L . n 
B 2 172 ASN 172 172 172 ASN ASN L . n 
B 2 173 LYS 173 173 173 LYS LYS L . n 
B 2 174 TYR 174 174 174 TYR TYR L . n 
B 2 175 ALA 175 175 175 ALA ALA L . n 
B 2 176 ALA 176 176 176 ALA ALA L . n 
B 2 177 SER 177 177 177 SER SER L . n 
B 2 178 SER 178 178 178 SER SER L . n 
B 2 179 TYR 179 179 179 TYR TYR L . n 
B 2 180 LEU 180 180 180 LEU LEU L . n 
B 2 181 SER 181 181 181 SER SER L . n 
B 2 182 LEU 182 182 182 LEU LEU L . n 
B 2 183 THR 183 183 183 THR THR L . n 
B 2 184 PRO 184 184 184 PRO PRO L . n 
B 2 185 GLU 185 185 185 GLU GLU L . n 
B 2 186 GLN 186 186 186 GLN GLN L . n 
B 2 187 TRP 187 187 187 TRP TRP L . n 
B 2 188 LYS 188 188 188 LYS LYS L . n 
B 2 189 SER 189 189 189 SER SER L . n 
B 2 190 HIS 190 190 190 HIS HIS L . n 
B 2 191 ARG 191 191 191 ARG ARG L . n 
B 2 192 SER 192 192 192 SER SER L . n 
B 2 193 TYR 193 193 193 TYR TYR L . n 
B 2 194 SER 194 194 194 SER SER L . n 
B 2 195 CYS 195 195 195 CYS CYS L . n 
B 2 196 GLN 196 196 196 GLN GLN L . n 
B 2 197 VAL 197 197 197 VAL VAL L . n 
B 2 198 THR 198 198 198 THR THR L . n 
B 2 199 HIS 199 199 199 HIS HIS L . n 
B 2 200 GLU 200 200 200 GLU GLU L . n 
B 2 201 GLY 201 201 201 GLY GLY L . n 
B 2 202 SER 202 202 202 SER SER L . n 
B 2 203 THR 203 203 203 THR THR L . n 
B 2 204 VAL 204 204 204 VAL VAL L . n 
B 2 205 GLU 205 205 205 GLU GLU L . n 
B 2 206 LYS 206 206 206 LYS LYS L . n 
B 2 207 THR 207 207 207 THR THR L . n 
B 2 208 VAL 208 208 208 VAL VAL L . n 
B 2 209 ALA 209 209 209 ALA ALA L . n 
B 2 210 PRO 210 210 210 PRO PRO L . n 
B 2 211 THR 211 211 211 THR THR L . n 
B 2 212 GLU 212 212 ?   ?   ?   L . n 
B 2 213 CYS 213 213 ?   ?   ?   L . n 
B 2 214 SER 214 214 ?   ?   ?   L . n 
C 3 1   ALA 1   52  52  ALA ALA E . n 
C 3 2   PRO 2   53  53  PRO PRO E . n 
C 3 3   LEU 3   54  54  LEU LEU E . n 
C 3 4   GLN 4   55  55  GLN GLN E . n 
C 3 5   LEU 5   56  56  LEU LEU E . n 
C 3 6   GLY 6   57  57  GLY GLY E . n 
C 3 7   ASN 7   58  58  ASN ASN E . n 
C 3 8   CYS 8   59  59  CYS CYS E . n 
C 3 9   SER 9   60  60  SER SER E . n 
C 3 10  ILE 10  61  61  ILE ILE E . n 
C 3 11  ALA 11  62  62  ALA ALA E . n 
C 3 12  GLY 12  63  63  GLY GLY E . n 
C 3 13  TRP 13  64  64  TRP TRP E . n 
C 3 14  ILE 14  65  65  ILE ILE E . n 
C 3 15  LEU 15  66  66  LEU LEU E . n 
C 3 16  GLY 16  67  67  GLY GLY E . n 
C 3 17  ASN 17  68  68  ASN ASN E . n 
C 3 18  PRO 18  69  69  PRO PRO E . n 
C 3 19  GLU 19  70  70  GLU GLU E . n 
C 3 20  CYS 20  71  71  CYS CYS E . n 
C 3 21  GLU 21  72  72  GLU GLU E . n 
C 3 22  SER 22  73  73  SER SER E . n 
C 3 23  LEU 23  74  74  LEU LEU E . n 
C 3 24  PHE 24  75  75  PHE PHE E . n 
C 3 25  SER 25  76  76  SER SER E . n 
C 3 26  LYS 26  77  77  LYS LYS E . n 
C 3 27  GLU 27  78  78  GLU GLU E . n 
C 3 28  SER 28  79  79  SER SER E . n 
C 3 29  TRP 29  80  80  TRP TRP E . n 
C 3 30  SER 30  81  81  SER SER E . n 
C 3 31  TYR 31  82  82  TYR TYR E . n 
C 3 32  ILE 32  83  83  ILE ILE E . n 
C 3 33  ALA 33  84  84  ALA ALA E . n 
C 3 34  GLU 34  85  85  GLU GLU E . n 
C 3 35  THR 35  86  86  THR THR E . n 
C 3 36  PRO 36  87  87  PRO PRO E . n 
C 3 37  ASN 37  88  88  ASN ASN E . n 
C 3 38  SER 38  89  89  SER SER E . n 
C 3 39  GLU 39  90  90  GLU GLU E . n 
C 3 40  ASN 40  91  91  ASN ASN E . n 
C 3 41  GLY 41  92  92  GLY GLY E . n 
C 3 42  THR 42  93  93  THR THR E . n 
C 3 43  CYS 43  94  94  CYS CYS E . n 
C 3 44  TYR 44  95  95  TYR TYR E . n 
C 3 45  PRO 45  96  96  PRO PRO E . n 
C 3 46  GLY 46  97  97  GLY GLY E . n 
C 3 47  TYR 47  98  98  TYR TYR E . n 
C 3 48  PHE 48  99  99  PHE PHE E . n 
C 3 49  ALA 49  100 100 ALA ALA E . n 
C 3 50  ASP 50  101 101 ASP ASP E . n 
C 3 51  TYR 51  102 102 TYR TYR E . n 
C 3 52  GLU 52  103 103 GLU GLU E . n 
C 3 53  GLU 53  104 104 GLU GLU E . n 
C 3 54  LEU 54  105 105 LEU LEU E . n 
C 3 55  ARG 55  106 106 ARG ARG E . n 
C 3 56  GLU 56  107 107 GLU GLU E . n 
C 3 57  GLN 57  108 108 GLN GLN E . n 
C 3 58  LEU 58  109 109 LEU LEU E . n 
C 3 59  SER 59  110 110 SER SER E . n 
C 3 60  SER 60  111 111 SER SER E . n 
C 3 61  VAL 61  112 112 VAL VAL E . n 
C 3 62  SER 62  113 113 SER SER E . n 
C 3 63  SER 63  114 114 SER SER E . n 
C 3 64  PHE 64  115 115 PHE PHE E . n 
C 3 65  GLU 65  116 116 GLU GLU E . n 
C 3 66  ARG 66  117 117 ARG ARG E . n 
C 3 67  PHE 67  118 118 PHE PHE E . n 
C 3 68  GLU 68  119 119 GLU GLU E . n 
C 3 69  ILE 69  120 120 ILE ILE E . n 
C 3 70  PHE 70  121 121 PHE PHE E . n 
C 3 71  PRO 71  122 122 PRO PRO E . n 
C 3 72  LYS 72  123 123 LYS LYS E . n 
C 3 73  GLU 73  124 124 GLU GLU E . n 
C 3 74  SER 74  125 125 SER SER E . n 
C 3 75  SER 75  126 126 SER SER E . n 
C 3 76  TRP 76  127 127 TRP TRP E . n 
C 3 77  PRO 77  128 128 PRO PRO E . n 
C 3 78  ASN 78  129 129 ASN ASN E . n 
C 3 79  HIS 79  130 130 HIS HIS E . n 
C 3 80  THR 80  131 131 THR THR E . n 
C 3 81  VAL 81  132 132 VAL VAL E . n 
C 3 82  THR 82  133 133 THR THR E . n 
C 3 83  LYS 83  133 133 LYS LYS E a n 
C 3 84  GLY 84  134 134 GLY GLY E . n 
C 3 85  VAL 85  135 135 VAL VAL E . n 
C 3 86  THR 86  136 136 THR THR E . n 
C 3 87  ALA 87  137 137 ALA ALA E . n 
C 3 88  SER 88  138 138 SER SER E . n 
C 3 89  CYS 89  139 139 CYS CYS E . n 
C 3 90  SER 90  140 140 SER SER E . n 
C 3 91  HIS 91  141 141 HIS HIS E . n 
C 3 92  ASN 92  142 142 ASN ASN E . n 
C 3 93  GLY 93  143 143 GLY GLY E . n 
C 3 94  LYS 94  144 144 LYS LYS E . n 
C 3 95  SER 95  145 145 SER SER E . n 
C 3 96  SER 96  146 146 SER SER E . n 
C 3 97  PHE 97  147 147 PHE PHE E . n 
C 3 98  TYR 98  148 148 TYR TYR E . n 
C 3 99  ARG 99  149 149 ARG ARG E . n 
C 3 100 ASN 100 150 150 ASN ASN E . n 
C 3 101 LEU 101 151 151 LEU LEU E . n 
C 3 102 LEU 102 152 152 LEU LEU E . n 
C 3 103 TRP 103 153 153 TRP TRP E . n 
C 3 104 LEU 104 154 154 LEU LEU E . n 
C 3 105 THR 105 155 155 THR THR E . n 
C 3 106 GLU 106 156 156 GLU GLU E . n 
C 3 107 LYS 107 157 157 LYS LYS E . n 
C 3 108 ASN 108 158 158 ASN ASN E . n 
C 3 109 GLY 109 159 159 GLY GLY E . n 
C 3 110 LEU 110 160 160 LEU LEU E . n 
C 3 111 TYR 111 161 161 TYR TYR E . n 
C 3 112 PRO 112 162 162 PRO PRO E . n 
C 3 113 ASN 113 163 163 ASN ASN E . n 
C 3 114 LEU 114 164 164 LEU LEU E . n 
C 3 115 SER 115 165 165 SER SER E . n 
C 3 116 LYS 116 166 166 LYS LYS E . n 
C 3 117 SER 117 167 167 SER SER E . n 
C 3 118 TYR 118 168 168 TYR TYR E . n 
C 3 119 VAL 119 169 169 VAL VAL E . n 
C 3 120 ASN 120 170 170 ASN ASN E . n 
C 3 121 ASN 121 171 171 ASN ASN E . n 
C 3 122 LYS 122 172 172 LYS LYS E . n 
C 3 123 GLU 123 173 173 GLU GLU E . n 
C 3 124 LYS 124 174 174 LYS LYS E . n 
C 3 125 GLU 125 175 175 GLU GLU E . n 
C 3 126 VAL 126 176 176 VAL VAL E . n 
C 3 127 LEU 127 177 177 LEU LEU E . n 
C 3 128 VAL 128 178 178 VAL VAL E . n 
C 3 129 LEU 129 179 179 LEU LEU E . n 
C 3 130 TRP 130 180 180 TRP TRP E . n 
C 3 131 GLY 131 181 181 GLY GLY E . n 
C 3 132 VAL 132 182 182 VAL VAL E . n 
C 3 133 HIS 133 183 183 HIS HIS E . n 
C 3 134 HIS 134 184 184 HIS HIS E . n 
C 3 135 PRO 135 185 185 PRO PRO E . n 
C 3 136 SER 136 186 186 SER SER E . n 
C 3 137 ASN 137 187 187 ASN ASN E . n 
C 3 138 ILE 138 188 188 ILE ILE E . n 
C 3 139 GLU 139 189 189 GLU GLU E . n 
C 3 140 ASP 140 190 190 ASP ASP E . n 
C 3 141 GLN 141 191 191 GLN GLN E . n 
C 3 142 ARG 142 192 192 ARG ARG E . n 
C 3 143 ALA 143 193 193 ALA ALA E . n 
C 3 144 ILE 144 194 194 ILE ILE E . n 
C 3 145 TYR 145 195 195 TYR TYR E . n 
C 3 146 HIS 146 196 196 HIS HIS E . n 
C 3 147 THR 147 197 197 THR THR E . n 
C 3 148 GLU 148 198 198 GLU GLU E . n 
C 3 149 ASN 149 199 199 ASN ASN E . n 
C 3 150 ALA 150 200 200 ALA ALA E . n 
C 3 151 TYR 151 201 201 TYR TYR E . n 
C 3 152 VAL 152 202 202 VAL VAL E . n 
C 3 153 SER 153 203 203 SER SER E . n 
C 3 154 VAL 154 204 204 VAL VAL E . n 
C 3 155 VAL 155 205 205 VAL VAL E . n 
C 3 156 SER 156 206 206 SER SER E . n 
C 3 157 SER 157 207 207 SER SER E . n 
C 3 158 HIS 158 208 208 HIS HIS E . n 
C 3 159 TYR 159 209 209 TYR TYR E . n 
C 3 160 SER 160 210 210 SER SER E . n 
C 3 161 ARG 161 211 211 ARG ARG E . n 
C 3 162 ARG 162 212 212 ARG ARG E . n 
C 3 163 PHE 163 213 213 PHE PHE E . n 
C 3 164 THR 164 214 214 THR THR E . n 
C 3 165 PRO 165 215 215 PRO PRO E . n 
C 3 166 GLU 166 216 216 GLU GLU E . n 
C 3 167 ILE 167 217 217 ILE ILE E . n 
C 3 168 ALA 168 218 218 ALA ALA E . n 
C 3 169 LYS 169 219 219 LYS LYS E . n 
C 3 170 ARG 170 220 220 ARG ARG E . n 
C 3 171 PRO 171 221 221 PRO PRO E . n 
C 3 172 LYS 172 222 222 LYS LYS E . n 
C 3 173 VAL 173 223 223 VAL VAL E . n 
C 3 174 ARG 174 224 224 ARG ARG E . n 
C 3 175 ASP 175 225 225 ASP ASP E . n 
C 3 176 GLN 176 226 226 GLN GLN E . n 
C 3 177 GLU 177 227 227 GLU GLU E . n 
C 3 178 GLY 178 228 228 GLY GLY E . n 
C 3 179 ARG 179 229 229 ARG ARG E . n 
C 3 180 ILE 180 230 230 ILE ILE E . n 
C 3 181 ASN 181 231 231 ASN ASN E . n 
C 3 182 TYR 182 232 232 TYR TYR E . n 
C 3 183 TYR 183 233 233 TYR TYR E . n 
C 3 184 TRP 184 234 234 TRP TRP E . n 
C 3 185 THR 185 235 235 THR THR E . n 
C 3 186 LEU 186 236 236 LEU LEU E . n 
C 3 187 LEU 187 237 237 LEU LEU E . n 
C 3 188 GLU 188 238 238 GLU GLU E . n 
C 3 189 PRO 189 239 239 PRO PRO E . n 
C 3 190 GLY 190 240 240 GLY GLY E . n 
C 3 191 ASP 191 241 241 ASP ASP E . n 
C 3 192 THR 192 242 242 THR THR E . n 
C 3 193 ILE 193 243 243 ILE ILE E . n 
C 3 194 ILE 194 244 244 ILE ILE E . n 
C 3 195 PHE 195 245 245 PHE PHE E . n 
C 3 196 GLU 196 246 246 GLU GLU E . n 
C 3 197 ALA 197 247 247 ALA ALA E . n 
C 3 198 ASN 198 248 248 ASN ASN E . n 
C 3 199 GLY 199 249 249 GLY GLY E . n 
C 3 200 ASN 200 250 250 ASN ASN E . n 
C 3 201 LEU 201 251 251 LEU LEU E . n 
C 3 202 ILE 202 252 252 ILE ILE E . n 
C 3 203 ALA 203 253 253 ALA ALA E . n 
C 3 204 PRO 204 254 254 PRO PRO E . n 
C 3 205 TRP 205 255 255 TRP TRP E . n 
C 3 206 TYR 206 256 256 TYR TYR E . n 
C 3 207 ALA 207 257 257 ALA ALA E . n 
C 3 208 PHE 208 258 258 PHE PHE E . n 
C 3 209 ALA 209 259 259 ALA ALA E . n 
C 3 210 LEU 210 260 260 LEU LEU E . n 
C 3 211 SER 211 261 261 SER SER E . n 
C 3 212 ARG 212 262 262 ARG ARG E . n 
C 3 213 GLY 213 263 263 GLY GLY E . n 
C 3 214 GLY 214 264 ?   ?   ?   E . n 
C 3 215 ALA 215 265 ?   ?   ?   E . n 
C 3 216 GLY 216 266 ?   ?   ?   E . n 
C 3 217 SER 217 267 ?   ?   ?   E . n 
C 3 218 SER 218 268 ?   ?   ?   E . n 
C 3 219 LEU 219 269 ?   ?   ?   E . n 
C 3 220 GLU 220 270 ?   ?   ?   E . n 
C 3 221 VAL 221 271 ?   ?   ?   E . n 
C 3 222 LEU 222 272 ?   ?   ?   E . n 
C 3 223 PHE 223 273 ?   ?   ?   E . n 
C 3 224 GLN 224 274 ?   ?   ?   E . n 
# 
_pdbx_nonpoly_scheme.asym_id         D 
_pdbx_nonpoly_scheme.entity_id       4 
_pdbx_nonpoly_scheme.mon_id          NAG 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     301 
_pdbx_nonpoly_scheme.auth_seq_num    264 
_pdbx_nonpoly_scheme.pdb_mon_id      NAG 
_pdbx_nonpoly_scheme.auth_mon_id     NAG 
_pdbx_nonpoly_scheme.pdb_strand_id   E 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.20.1_4487 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .           2 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? .           3 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .           4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9AZV 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     76.277 
_cell.length_a_esd                 ? 
_cell.length_b                     93.467 
_cell.length_b_esd                 ? 
_cell.length_c                     108.852 
_cell.length_c_esd                 ? 
_cell.volume                       776047.529 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9AZV 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                18 
_symmetry.space_group_name_Hall            'P 2 2ab' 
_symmetry.space_group_name_H-M             'P 21 21 2' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9AZV 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.58 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          52.27 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '20% PEG 8K, 100 mM HEPES, pH 7, 100 mM MgSO4' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            291 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2021-11-24 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97918 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'APS BEAMLINE 24-ID-E' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97918 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   24-ID-E 
_diffrn_source.pdbx_synchrotron_site       APS 
# 
_reflns.B_iso_Wilson_estimate                          89.38 
_reflns.entry_id                                       9AZV 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              3.16 
_reflns.d_resolution_low                               47.03 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     13883 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.7 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                5.8 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          10.81 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.996 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    3.16 
_reflns_shell.d_res_low                                     3.35 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           2.18 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2181 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.901 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               96.79 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9AZV 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            3.16 
_refine.ls_d_res_low                             47.03 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     13861 
_refine.ls_number_reflns_R_free                  1385 
_refine.ls_number_reflns_R_work                  12476 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.58 
_refine.ls_percent_reflns_R_free                 9.99 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2421 
_refine.ls_R_factor_R_free                       0.2873 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2371 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.36 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 32.5724 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.4806 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       3.16 
_refine_hist.d_res_low                        47.03 
_refine_hist.number_atoms_solvent             0 
_refine_hist.number_atoms_total               5032 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        5018 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         14 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0018 ? 5169 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.4840 ? 7053 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0440 ? 775  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0049 ? 907  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 4.0224 ? 709  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 3.16 3.27  . . 132 1207 98.10  . . . . 0.3488 . . . . . . . . . . . 0.4253 
'X-RAY DIFFRACTION' 3.27 3.40  . . 135 1216 99.56  . . . . 0.2885 . . . . . . . . . . . 0.3955 
'X-RAY DIFFRACTION' 3.40 3.56  . . 136 1222 99.49  . . . . 0.2623 . . . . . . . . . . . 0.3084 
'X-RAY DIFFRACTION' 3.56 3.74  . . 138 1239 99.85  . . . . 0.2656 . . . . . . . . . . . 0.3373 
'X-RAY DIFFRACTION' 3.74 3.98  . . 136 1226 99.63  . . . . 0.2540 . . . . . . . . . . . 0.2897 
'X-RAY DIFFRACTION' 3.98 4.28  . . 139 1243 99.93  . . . . 0.2159 . . . . . . . . . . . 0.2915 
'X-RAY DIFFRACTION' 4.28 4.71  . . 139 1247 99.93  . . . . 0.2028 . . . . . . . . . . . 0.2576 
'X-RAY DIFFRACTION' 4.72 5.40  . . 139 1251 99.64  . . . . 0.1982 . . . . . . . . . . . 0.2453 
'X-RAY DIFFRACTION' 5.40 6.79  . . 140 1276 100.00 . . . . 0.2554 . . . . . . . . . . . 0.2963 
'X-RAY DIFFRACTION' 6.80 47.03 . . 151 1349 99.67  . . . . 0.2301 . . . . . . . . . . . 0.2634 
# 
_struct.entry_id                     9AZV 
_struct.title                        
'CH67 Fab bound to A/Massachusetts/1/1990 influenza hemagglutinin head with a G189E mutation (2)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9AZV 
_struct_keywords.text            'antibody, influenza, hemagglutinin, UCA, ANTIVIRAL PROTEIN, VIRAL PROTEIN-IMMUNE SYSTEM complex' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN/IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 9AZV         9AZV   ? 1 ? 1  
2 PDB 9AZV         9AZV   ? 2 ? 1  
3 UNP Q07775_9INFA Q07775 ? 3 
;APLQLGNCSIAGWILGNPECESLFSKESWSYIAETPNSENGTCYPGYFADYEELREQLSSVSSFERFEIFPKESSWPNHT
VTKGVTASCSHNGKSSFYRNLLWLTEKNGLYPNLSKSYVNNKEKEVLVLWGVHHPSNIGDQRAIYHTENAYVSVVSSHYS
RRFTPEIAKRPKVRDQEGRINYYWTLLEPGDTIIFEANGNLIAPWYAFALSRG
;
65 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9AZV H 1 ? 250 ? 9AZV   1  ? 250 ? 1  250 
2 2 9AZV L 1 ? 214 ? 9AZV   1  ? 214 ? 1  214 
3 3 9AZV E 1 ? 213 ? Q07775 65 ? 277 ? 52 263 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
3 9AZV GLU E 139 ? UNP Q07775 GLY 203 'engineered mutation' 189 1  
3 9AZV GLY E 214 ? UNP Q07775 ?   ?   'expression tag'      264 2  
3 9AZV ALA E 215 ? UNP Q07775 ?   ?   'expression tag'      265 3  
3 9AZV GLY E 216 ? UNP Q07775 ?   ?   'expression tag'      266 4  
3 9AZV SER E 217 ? UNP Q07775 ?   ?   'expression tag'      267 5  
3 9AZV SER E 218 ? UNP Q07775 ?   ?   'expression tag'      268 6  
3 9AZV LEU E 219 ? UNP Q07775 ?   ?   'expression tag'      269 7  
3 9AZV GLU E 220 ? UNP Q07775 ?   ?   'expression tag'      270 8  
3 9AZV VAL E 221 ? UNP Q07775 ?   ?   'expression tag'      271 9  
3 9AZV LEU E 222 ? UNP Q07775 ?   ?   'expression tag'      272 10 
3 9AZV PHE E 223 ? UNP Q07775 ?   ?   'expression tag'      273 11 
3 9AZV GLN E 224 ? UNP Q07775 ?   ?   'expression tag'      274 12 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   trimeric 
_pdbx_struct_assembly.oligomeric_count     3 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ARG A 87  ? THR A 91  ? ARG H 87  THR H 91  5 ? 5  
HELX_P HELX_P2  AA2 SER A 105 ? TYR A 109 ? SER H 105 TYR H 109 5 ? 5  
HELX_P HELX_P3  AA3 SER A 169 ? ALA A 171 ? SER H 169 ALA H 171 5 ? 3  
HELX_P HELX_P4  AA4 LYS A 214 ? ASN A 217 ? LYS H 214 ASN H 217 5 ? 4  
HELX_P HELX_P5  AA5 GLU B 78  ? GLU B 82  ? GLU L 78  GLU L 82  5 ? 5  
HELX_P HELX_P6  AA6 SER B 123 ? GLN B 128 ? SER L 123 GLN L 128 1 ? 6  
HELX_P HELX_P7  AA7 THR B 183 ? HIS B 190 ? THR L 183 HIS L 190 1 ? 8  
HELX_P HELX_P8  AA8 SER C 9   ? GLY C 16  ? SER E 60  GLY E 67  1 ? 8  
HELX_P HELX_P9  AA9 ASP C 50  ? SER C 59  ? ASP E 101 SER E 110 1 ? 10 
HELX_P HELX_P10 AB1 PRO C 71  ? TRP C 76  ? PRO E 122 TRP E 127 1 ? 6  
HELX_P HELX_P11 AB2 ASN C 137 ? HIS C 146 ? ASN E 187 HIS E 196 1 ? 10 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ?   ? A CYS 22  SG  ? ? ? 1_555 A CYS 96  SG ? ? H CYS 22  H CYS 96  1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf2 disulf ?   ? A CYS 153 SG  ? ? ? 1_555 A CYS 209 SG ? ? H CYS 153 H CYS 209 1_555 ? ? ? ? ? ? ? 2.033 ? ?               
disulf3 disulf ?   ? B CYS 22  SG  ? ? ? 1_555 B CYS 87  SG ? ? L CYS 22  L CYS 87  1_555 ? ? ? ? ? ? ? 2.033 ? ?               
disulf4 disulf ?   ? B CYS 136 SG  ? ? ? 1_555 B CYS 195 SG ? ? L CYS 136 L CYS 195 1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf5 disulf ?   ? C CYS 8   SG  ? ? ? 1_555 C CYS 20  SG ? ? E CYS 59  E CYS 71  1_555 ? ? ? ? ? ? ? 2.028 ? ?               
disulf6 disulf ?   ? C CYS 43  SG  ? ? ? 1_555 C CYS 89  SG ? ? E CYS 94  E CYS 139 1_555 ? ? ? ? ? ? ? 2.030 ? ?               
covale1 covale one ? C ASN 7   ND2 ? ? ? 1_555 D NAG .   C1 ? ? E ASN 58  E NAG 301 1_555 ? ? ? ? ? ? ? 1.446 ? N-Glycosylation 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 NAG D .   ? ASN C 7   ? NAG E 301 ? 1_555 ASN E 58  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2 CYS A 22  ? CYS A 96  ? CYS H 22  ? 1_555 CYS H 96  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
3 CYS A 153 ? CYS A 209 ? CYS H 153 ? 1_555 CYS H 209 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
4 CYS B 22  ? CYS B 87  ? CYS L 22  ? 1_555 CYS L 87  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
5 CYS B 136 ? CYS B 195 ? CYS L 136 ? 1_555 CYS L 195 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
6 CYS C 8   ? CYS C 20  ? CYS E 59  ? 1_555 CYS E 71  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
7 CYS C 43  ? CYS C 89  ? CYS E 94  ? 1_555 CYS E 139 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 PHE 159 A . ? PHE 159 H PRO 160 A ? PRO 160 H 1 -4.78 
2 GLU 161 A . ? GLU 161 H PRO 162 A ? PRO 162 H 1 -0.92 
3 TYR 142 B . ? TYR 142 L PRO 143 B ? PRO 143 L 1 0.78  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 6 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 3 ? 
AA6 ? 5 ? 
AA7 ? 3 ? 
AA8 ? 4 ? 
AA9 ? 4 ? 
AB1 ? 4 ? 
AB2 ? 5 ? 
AB3 ? 4 ? 
AB4 ? 2 ? 
AB5 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA2 5 6 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA6 1 2 ? parallel      
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA6 4 5 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB2 4 5 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLN A 3   ? GLN A 6   ? GLN H 3   GLN H 6   
AA1 2 VAL A 18  ? SER A 25  ? VAL H 18  SER H 25  
AA1 3 THR A 78  ? LEU A 83  ? THR H 78  LEU H 83  
AA1 4 VAL A 68  ? ASP A 73  ? VAL H 68  ASP H 73  
AA2 1 GLU A 10  ? VAL A 11  ? GLU H 10  VAL H 11  
AA2 2 THR A 120 ? THR A 123 ? THR H 120 THR H 123 
AA2 3 ALA A 92  ? ARG A 98  ? ALA H 92  ARG H 98  
AA2 4 ILE A 34  ? GLN A 39  ? ILE H 34  GLN H 39  
AA2 5 LEU A 45  ? ILE A 51  ? LEU H 45  ILE H 51  
AA2 6 THR A 58  ? TYR A 60  ? THR H 58  TYR H 60  
AA3 1 SER A 133 ? LEU A 137 ? SER H 133 LEU H 137 
AA3 2 THR A 148 ? TYR A 158 ? THR H 148 TYR H 158 
AA3 3 TYR A 189 ? PRO A 198 ? TYR H 189 PRO H 198 
AA3 4 VAL A 176 ? THR A 178 ? VAL H 176 THR H 178 
AA4 1 SER A 133 ? LEU A 137 ? SER H 133 LEU H 137 
AA4 2 THR A 148 ? TYR A 158 ? THR H 148 TYR H 158 
AA4 3 TYR A 189 ? PRO A 198 ? TYR H 189 PRO H 198 
AA4 4 VAL A 182 ? LEU A 183 ? VAL H 182 LEU H 183 
AA5 1 THR A 164 ? TRP A 167 ? THR H 164 TRP H 167 
AA5 2 ILE A 208 ? HIS A 213 ? ILE H 208 HIS H 213 
AA5 3 THR A 218 ? ARG A 223 ? THR H 218 ARG H 223 
AA6 1 SER B 9   ? VAL B 12  ? SER L 9   VAL L 12  
AA6 2 THR B 103 ? VAL B 107 ? THR L 103 VAL L 107 
AA6 3 ALA B 83  ? GLN B 88  ? ALA L 83  GLN L 88  
AA6 4 ASP B 33  ? GLN B 37  ? ASP L 33  GLN L 37  
AA6 5 VAL B 44  ? VAL B 47  ? VAL L 44  VAL L 47  
AA7 1 ALA B 18  ? GLY B 23  ? ALA L 18  GLY L 23  
AA7 2 THR B 69  ? ILE B 74  ? THR L 69  ILE L 74  
AA7 3 PHE B 61  ? SER B 64  ? PHE L 61  SER L 64  
AA8 1 SER B 116 ? PHE B 120 ? SER L 116 PHE L 120 
AA8 2 ALA B 132 ? PHE B 141 ? ALA L 132 PHE L 141 
AA8 3 TYR B 174 ? LEU B 182 ? TYR L 174 LEU L 182 
AA8 4 VAL B 161 ? THR B 163 ? VAL L 161 THR L 163 
AA9 1 SER B 116 ? PHE B 120 ? SER L 116 PHE L 120 
AA9 2 ALA B 132 ? PHE B 141 ? ALA L 132 PHE L 141 
AA9 3 TYR B 174 ? LEU B 182 ? TYR L 174 LEU L 182 
AA9 4 SER B 167 ? LYS B 168 ? SER L 167 LYS L 168 
AB1 1 SER B 155 ? VAL B 157 ? SER L 155 VAL L 157 
AB1 2 THR B 147 ? ALA B 152 ? THR L 147 ALA L 152 
AB1 3 TYR B 193 ? HIS B 199 ? TYR L 193 HIS L 199 
AB1 4 SER B 202 ? VAL B 208 ? SER L 202 VAL L 208 
AB2 1 SER C 63  ? PHE C 67  ? SER E 114 PHE E 118 
AB2 2 ALA C 207 ? SER C 211 ? ALA E 257 SER E 261 
AB2 3 GLU C 125 ? HIS C 134 ? GLU E 175 HIS E 184 
AB2 4 LEU C 201 ? PRO C 204 ? LEU E 251 PRO E 254 
AB2 5 LEU C 101 ? TRP C 103 ? LEU E 151 TRP E 153 
AB3 1 SER C 63  ? PHE C 67  ? SER E 114 PHE E 118 
AB3 2 ALA C 207 ? SER C 211 ? ALA E 257 SER E 261 
AB3 3 GLU C 125 ? HIS C 134 ? GLU E 175 HIS E 184 
AB3 4 ARG C 179 ? LEU C 187 ? ARG E 229 LEU E 237 
AB4 1 THR C 86  ? HIS C 91  ? THR E 136 HIS E 141 
AB4 2 LYS C 94  ? SER C 96  ? LYS E 144 SER E 146 
AB5 1 LEU C 114 ? VAL C 119 ? LEU E 164 VAL E 169 
AB5 2 THR C 192 ? ALA C 197 ? THR E 242 ALA E 247 
AB5 3 VAL C 152 ? VAL C 155 ? VAL E 202 VAL E 205 
AB5 4 SER C 160 ? PHE C 163 ? SER E 210 PHE E 213 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N VAL A 5   ? N VAL H 5   O LYS A 23  ? O LYS H 23  
AA1 2 3 N VAL A 18  ? N VAL H 18  O LEU A 83  ? O LEU H 83  
AA1 3 4 O GLU A 82  ? O GLU H 82  N THR A 69  ? N THR H 69  
AA2 1 2 N GLU A 10  ? N GLU H 10  O ALA A 121 ? O ALA H 121 
AA2 2 3 O VAL A 122 ? O VAL H 122 N ALA A 92  ? N ALA H 92  
AA2 3 4 O ALA A 97  ? O ALA H 97  N HIS A 35  ? N HIS H 35  
AA2 4 5 N TRP A 36  ? N TRP H 36  O MET A 48  ? O MET H 48  
AA2 5 6 N TRP A 50  ? N TRP H 50  O LYS A 59  ? O LYS H 59  
AA3 1 2 N PHE A 135 ? N PHE H 135 O LEU A 154 ? O LEU H 154 
AA3 2 3 N ALA A 149 ? N ALA H 149 O VAL A 197 ? O VAL H 197 
AA3 3 4 O VAL A 194 ? O VAL H 194 N HIS A 177 ? N HIS H 177 
AA4 1 2 N PHE A 135 ? N PHE H 135 O LEU A 154 ? O LEU H 154 
AA4 2 3 N ALA A 149 ? N ALA H 149 O VAL A 197 ? O VAL H 197 
AA4 3 4 O SER A 190 ? O SER H 190 N VAL A 182 ? N VAL H 182 
AA5 1 2 N SER A 166 ? N SER H 166 O ASN A 210 ? O ASN H 210 
AA5 2 3 N HIS A 213 ? N HIS H 213 O THR A 218 ? O THR H 218 
AA6 1 2 N VAL B 10  ? N VAL L 10  O THR B 106 ? O THR L 106 
AA6 2 3 O LEU B 105 ? O LEU L 105 N ALA B 83  ? N ALA L 83  
AA6 3 4 O GLN B 88  ? O GLN L 88  N ASP B 33  ? N ASP L 33  
AA6 4 5 N GLN B 36  ? N GLN L 36  O VAL B 44  ? O VAL L 44  
AA7 1 2 N CYS B 22  ? N CYS L 22  O ALA B 70  ? O ALA L 70  
AA7 2 3 O THR B 73  ? O THR L 73  N SER B 62  ? N SER L 62  
AA8 1 2 N PHE B 120 ? N PHE L 120 O VAL B 135 ? O VAL L 135 
AA8 2 3 N ILE B 138 ? N ILE L 138 O ALA B 176 ? O ALA L 176 
AA8 3 4 O TYR B 179 ? O TYR L 179 N GLU B 162 ? N GLU L 162 
AA9 1 2 N PHE B 120 ? N PHE L 120 O VAL B 135 ? O VAL L 135 
AA9 2 3 N ILE B 138 ? N ILE L 138 O ALA B 176 ? O ALA L 176 
AA9 3 4 O ALA B 175 ? O ALA L 175 N SER B 167 ? N SER L 167 
AB1 1 2 O SER B 155 ? O SER L 155 N ALA B 152 ? N ALA L 152 
AB1 2 3 N THR B 147 ? N THR L 147 O THR B 198 ? O THR L 198 
AB1 3 4 N CYS B 195 ? N CYS L 195 O LYS B 206 ? O LYS L 206 
AB2 1 2 N PHE C 67  ? N PHE E 118 O ALA C 207 ? O ALA E 257 
AB2 2 3 O PHE C 208 ? O PHE E 258 N LEU C 127 ? N LEU E 177 
AB2 3 4 N GLY C 131 ? N GLY E 181 O ILE C 202 ? O ILE E 252 
AB2 4 5 O ALA C 203 ? O ALA E 253 N LEU C 102 ? N LEU E 152 
AB3 1 2 N PHE C 67  ? N PHE E 118 O ALA C 207 ? O ALA E 257 
AB3 2 3 O PHE C 208 ? O PHE E 258 N LEU C 127 ? N LEU E 177 
AB3 3 4 N HIS C 134 ? N HIS E 184 O ARG C 179 ? O ARG E 229 
AB4 1 2 N HIS C 91  ? N HIS E 141 O LYS C 94  ? O LYS E 144 
AB5 1 2 N LYS C 116 ? N LYS E 166 O PHE C 195 ? O PHE E 245 
AB5 2 3 O GLU C 196 ? O GLU E 246 N SER C 153 ? N SER E 203 
AB5 3 4 N VAL C 152 ? N VAL E 202 O PHE C 163 ? O PHE E 213 
# 
_pdbx_entry_details.entry_id                   9AZV 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 VAL H 124 ? ? -87.49  -78.76  
2  1 SER H 125 ? ? 30.79   49.58   
3  1 SER H 140 ? ? -69.21  -178.98 
4  1 SER H 141 ? ? 63.13   -177.15 
5  1 ILE L 27  ? ? 58.45   -160.69 
6  1 LYS L 30  ? ? 38.52   47.61   
7  1 ARG L 31  ? ? 58.41   -77.70  
8  1 VAL L 32  ? ? 61.40   98.87   
9  1 GLU L 49  ? ? 54.04   -119.28 
10 1 SER L 51  ? ? 56.41   -103.56 
11 1 SER L 55  ? ? -120.13 -60.48  
12 1 THR L 68  ? ? -93.99  33.01   
13 1 LEU E 74  ? ? -94.99  -60.24  
14 1 ASN E 91  ? ? -68.59  5.54    
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z           
2 x+1/2,-y+1/2,-z 
3 -x+1/2,y+1/2,-z 
4 -x,-y,z         
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 H SER 228 ? A SER 228 
2  1 Y 1 H CYS 229 ? A CYS 229 
3  1 Y 1 H ASP 230 ? A ASP 230 
4  1 Y 1 H LYS 231 ? A LYS 231 
5  1 Y 1 H GLY 232 ? A GLY 232 
6  1 Y 1 H SER 233 ? A SER 233 
7  1 Y 1 H SER 234 ? A SER 234 
8  1 Y 1 H LEU 235 ? A LEU 235 
9  1 Y 1 H GLU 236 ? A GLU 236 
10 1 Y 1 H VAL 237 ? A VAL 237 
11 1 Y 1 H LEU 238 ? A LEU 238 
12 1 Y 1 H PHE 239 ? A PHE 239 
13 1 Y 1 H GLN 240 ? A GLN 240 
14 1 Y 1 H GLY 241 ? A GLY 241 
15 1 Y 1 H PRO 242 ? A PRO 242 
16 1 Y 1 H LEU 243 ? A LEU 243 
17 1 Y 1 H GLY 244 ? A GLY 244 
18 1 Y 1 H HIS 245 ? A HIS 245 
19 1 Y 1 H HIS 246 ? A HIS 246 
20 1 Y 1 H HIS 247 ? A HIS 247 
21 1 Y 1 H HIS 248 ? A HIS 248 
22 1 Y 1 H HIS 249 ? A HIS 249 
23 1 Y 1 H HIS 250 ? A HIS 250 
24 1 Y 1 L GLN 1   ? B GLN 1   
25 1 Y 1 L GLU 212 ? B GLU 212 
26 1 Y 1 L CYS 213 ? B CYS 213 
27 1 Y 1 L SER 214 ? B SER 214 
28 1 Y 1 E GLY 264 ? C GLY 214 
29 1 Y 1 E ALA 265 ? C ALA 215 
30 1 Y 1 E GLY 266 ? C GLY 216 
31 1 Y 1 E SER 267 ? C SER 217 
32 1 Y 1 E SER 268 ? C SER 218 
33 1 Y 1 E LEU 269 ? C LEU 219 
34 1 Y 1 E GLU 270 ? C GLU 220 
35 1 Y 1 E VAL 271 ? C VAL 221 
36 1 Y 1 E LEU 272 ? C LEU 222 
37 1 Y 1 E PHE 273 ? C PHE 223 
38 1 Y 1 E GLN 274 ? C GLN 224 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
NAG C1   C N R 247 
NAG C2   C N R 248 
NAG C3   C N R 249 
NAG C4   C N S 250 
NAG C5   C N R 251 
NAG C6   C N N 252 
NAG C7   C N N 253 
NAG C8   C N N 254 
NAG N2   N N N 255 
NAG O1   O N N 256 
NAG O3   O N N 257 
NAG O4   O N N 258 
NAG O5   O N N 259 
NAG O6   O N N 260 
NAG O7   O N N 261 
NAG H1   H N N 262 
NAG H2   H N N 263 
NAG H3   H N N 264 
NAG H4   H N N 265 
NAG H5   H N N 266 
NAG H61  H N N 267 
NAG H62  H N N 268 
NAG H81  H N N 269 
NAG H82  H N N 270 
NAG H83  H N N 271 
NAG HN2  H N N 272 
NAG HO1  H N N 273 
NAG HO3  H N N 274 
NAG HO4  H N N 275 
NAG HO6  H N N 276 
PHE N    N N N 277 
PHE CA   C N S 278 
PHE C    C N N 279 
PHE O    O N N 280 
PHE CB   C N N 281 
PHE CG   C Y N 282 
PHE CD1  C Y N 283 
PHE CD2  C Y N 284 
PHE CE1  C Y N 285 
PHE CE2  C Y N 286 
PHE CZ   C Y N 287 
PHE OXT  O N N 288 
PHE H    H N N 289 
PHE H2   H N N 290 
PHE HA   H N N 291 
PHE HB2  H N N 292 
PHE HB3  H N N 293 
PHE HD1  H N N 294 
PHE HD2  H N N 295 
PHE HE1  H N N 296 
PHE HE2  H N N 297 
PHE HZ   H N N 298 
PHE HXT  H N N 299 
PRO N    N N N 300 
PRO CA   C N S 301 
PRO C    C N N 302 
PRO O    O N N 303 
PRO CB   C N N 304 
PRO CG   C N N 305 
PRO CD   C N N 306 
PRO OXT  O N N 307 
PRO H    H N N 308 
PRO HA   H N N 309 
PRO HB2  H N N 310 
PRO HB3  H N N 311 
PRO HG2  H N N 312 
PRO HG3  H N N 313 
PRO HD2  H N N 314 
PRO HD3  H N N 315 
PRO HXT  H N N 316 
SER N    N N N 317 
SER CA   C N S 318 
SER C    C N N 319 
SER O    O N N 320 
SER CB   C N N 321 
SER OG   O N N 322 
SER OXT  O N N 323 
SER H    H N N 324 
SER H2   H N N 325 
SER HA   H N N 326 
SER HB2  H N N 327 
SER HB3  H N N 328 
SER HG   H N N 329 
SER HXT  H N N 330 
THR N    N N N 331 
THR CA   C N S 332 
THR C    C N N 333 
THR O    O N N 334 
THR CB   C N R 335 
THR OG1  O N N 336 
THR CG2  C N N 337 
THR OXT  O N N 338 
THR H    H N N 339 
THR H2   H N N 340 
THR HA   H N N 341 
THR HB   H N N 342 
THR HG1  H N N 343 
THR HG21 H N N 344 
THR HG22 H N N 345 
THR HG23 H N N 346 
THR HXT  H N N 347 
TRP N    N N N 348 
TRP CA   C N S 349 
TRP C    C N N 350 
TRP O    O N N 351 
TRP CB   C N N 352 
TRP CG   C Y N 353 
TRP CD1  C Y N 354 
TRP CD2  C Y N 355 
TRP NE1  N Y N 356 
TRP CE2  C Y N 357 
TRP CE3  C Y N 358 
TRP CZ2  C Y N 359 
TRP CZ3  C Y N 360 
TRP CH2  C Y N 361 
TRP OXT  O N N 362 
TRP H    H N N 363 
TRP H2   H N N 364 
TRP HA   H N N 365 
TRP HB2  H N N 366 
TRP HB3  H N N 367 
TRP HD1  H N N 368 
TRP HE1  H N N 369 
TRP HE3  H N N 370 
TRP HZ2  H N N 371 
TRP HZ3  H N N 372 
TRP HH2  H N N 373 
TRP HXT  H N N 374 
TYR N    N N N 375 
TYR CA   C N S 376 
TYR C    C N N 377 
TYR O    O N N 378 
TYR CB   C N N 379 
TYR CG   C Y N 380 
TYR CD1  C Y N 381 
TYR CD2  C Y N 382 
TYR CE1  C Y N 383 
TYR CE2  C Y N 384 
TYR CZ   C Y N 385 
TYR OH   O N N 386 
TYR OXT  O N N 387 
TYR H    H N N 388 
TYR H2   H N N 389 
TYR HA   H N N 390 
TYR HB2  H N N 391 
TYR HB3  H N N 392 
TYR HD1  H N N 393 
TYR HD2  H N N 394 
TYR HE1  H N N 395 
TYR HE2  H N N 396 
TYR HH   H N N 397 
TYR HXT  H N N 398 
VAL N    N N N 399 
VAL CA   C N S 400 
VAL C    C N N 401 
VAL O    O N N 402 
VAL CB   C N N 403 
VAL CG1  C N N 404 
VAL CG2  C N N 405 
VAL OXT  O N N 406 
VAL H    H N N 407 
VAL H2   H N N 408 
VAL HA   H N N 409 
VAL HB   H N N 410 
VAL HG11 H N N 411 
VAL HG12 H N N 412 
VAL HG13 H N N 413 
VAL HG21 H N N 414 
VAL HG22 H N N 415 
VAL HG23 H N N 416 
VAL HXT  H N N 417 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
NAG C1  C2   sing N N 235 
NAG C1  O1   sing N N 236 
NAG C1  O5   sing N N 237 
NAG C1  H1   sing N N 238 
NAG C2  C3   sing N N 239 
NAG C2  N2   sing N N 240 
NAG C2  H2   sing N N 241 
NAG C3  C4   sing N N 242 
NAG C3  O3   sing N N 243 
NAG C3  H3   sing N N 244 
NAG C4  C5   sing N N 245 
NAG C4  O4   sing N N 246 
NAG C4  H4   sing N N 247 
NAG C5  C6   sing N N 248 
NAG C5  O5   sing N N 249 
NAG C5  H5   sing N N 250 
NAG C6  O6   sing N N 251 
NAG C6  H61  sing N N 252 
NAG C6  H62  sing N N 253 
NAG C7  C8   sing N N 254 
NAG C7  N2   sing N N 255 
NAG C7  O7   doub N N 256 
NAG C8  H81  sing N N 257 
NAG C8  H82  sing N N 258 
NAG C8  H83  sing N N 259 
NAG N2  HN2  sing N N 260 
NAG O1  HO1  sing N N 261 
NAG O3  HO3  sing N N 262 
NAG O4  HO4  sing N N 263 
NAG O6  HO6  sing N N 264 
PHE N   CA   sing N N 265 
PHE N   H    sing N N 266 
PHE N   H2   sing N N 267 
PHE CA  C    sing N N 268 
PHE CA  CB   sing N N 269 
PHE CA  HA   sing N N 270 
PHE C   O    doub N N 271 
PHE C   OXT  sing N N 272 
PHE CB  CG   sing N N 273 
PHE CB  HB2  sing N N 274 
PHE CB  HB3  sing N N 275 
PHE CG  CD1  doub Y N 276 
PHE CG  CD2  sing Y N 277 
PHE CD1 CE1  sing Y N 278 
PHE CD1 HD1  sing N N 279 
PHE CD2 CE2  doub Y N 280 
PHE CD2 HD2  sing N N 281 
PHE CE1 CZ   doub Y N 282 
PHE CE1 HE1  sing N N 283 
PHE CE2 CZ   sing Y N 284 
PHE CE2 HE2  sing N N 285 
PHE CZ  HZ   sing N N 286 
PHE OXT HXT  sing N N 287 
PRO N   CA   sing N N 288 
PRO N   CD   sing N N 289 
PRO N   H    sing N N 290 
PRO CA  C    sing N N 291 
PRO CA  CB   sing N N 292 
PRO CA  HA   sing N N 293 
PRO C   O    doub N N 294 
PRO C   OXT  sing N N 295 
PRO CB  CG   sing N N 296 
PRO CB  HB2  sing N N 297 
PRO CB  HB3  sing N N 298 
PRO CG  CD   sing N N 299 
PRO CG  HG2  sing N N 300 
PRO CG  HG3  sing N N 301 
PRO CD  HD2  sing N N 302 
PRO CD  HD3  sing N N 303 
PRO OXT HXT  sing N N 304 
SER N   CA   sing N N 305 
SER N   H    sing N N 306 
SER N   H2   sing N N 307 
SER CA  C    sing N N 308 
SER CA  CB   sing N N 309 
SER CA  HA   sing N N 310 
SER C   O    doub N N 311 
SER C   OXT  sing N N 312 
SER CB  OG   sing N N 313 
SER CB  HB2  sing N N 314 
SER CB  HB3  sing N N 315 
SER OG  HG   sing N N 316 
SER OXT HXT  sing N N 317 
THR N   CA   sing N N 318 
THR N   H    sing N N 319 
THR N   H2   sing N N 320 
THR CA  C    sing N N 321 
THR CA  CB   sing N N 322 
THR CA  HA   sing N N 323 
THR C   O    doub N N 324 
THR C   OXT  sing N N 325 
THR CB  OG1  sing N N 326 
THR CB  CG2  sing N N 327 
THR CB  HB   sing N N 328 
THR OG1 HG1  sing N N 329 
THR CG2 HG21 sing N N 330 
THR CG2 HG22 sing N N 331 
THR CG2 HG23 sing N N 332 
THR OXT HXT  sing N N 333 
TRP N   CA   sing N N 334 
TRP N   H    sing N N 335 
TRP N   H2   sing N N 336 
TRP CA  C    sing N N 337 
TRP CA  CB   sing N N 338 
TRP CA  HA   sing N N 339 
TRP C   O    doub N N 340 
TRP C   OXT  sing N N 341 
TRP CB  CG   sing N N 342 
TRP CB  HB2  sing N N 343 
TRP CB  HB3  sing N N 344 
TRP CG  CD1  doub Y N 345 
TRP CG  CD2  sing Y N 346 
TRP CD1 NE1  sing Y N 347 
TRP CD1 HD1  sing N N 348 
TRP CD2 CE2  doub Y N 349 
TRP CD2 CE3  sing Y N 350 
TRP NE1 CE2  sing Y N 351 
TRP NE1 HE1  sing N N 352 
TRP CE2 CZ2  sing Y N 353 
TRP CE3 CZ3  doub Y N 354 
TRP CE3 HE3  sing N N 355 
TRP CZ2 CH2  doub Y N 356 
TRP CZ2 HZ2  sing N N 357 
TRP CZ3 CH2  sing Y N 358 
TRP CZ3 HZ3  sing N N 359 
TRP CH2 HH2  sing N N 360 
TRP OXT HXT  sing N N 361 
TYR N   CA   sing N N 362 
TYR N   H    sing N N 363 
TYR N   H2   sing N N 364 
TYR CA  C    sing N N 365 
TYR CA  CB   sing N N 366 
TYR CA  HA   sing N N 367 
TYR C   O    doub N N 368 
TYR C   OXT  sing N N 369 
TYR CB  CG   sing N N 370 
TYR CB  HB2  sing N N 371 
TYR CB  HB3  sing N N 372 
TYR CG  CD1  doub Y N 373 
TYR CG  CD2  sing Y N 374 
TYR CD1 CE1  sing Y N 375 
TYR CD1 HD1  sing N N 376 
TYR CD2 CE2  doub Y N 377 
TYR CD2 HD2  sing N N 378 
TYR CE1 CZ   doub Y N 379 
TYR CE1 HE1  sing N N 380 
TYR CE2 CZ   sing Y N 381 
TYR CE2 HE2  sing N N 382 
TYR CZ  OH   sing N N 383 
TYR OH  HH   sing N N 384 
TYR OXT HXT  sing N N 385 
VAL N   CA   sing N N 386 
VAL N   H    sing N N 387 
VAL N   H2   sing N N 388 
VAL CA  C    sing N N 389 
VAL CA  CB   sing N N 390 
VAL CA  HA   sing N N 391 
VAL C   O    doub N N 392 
VAL C   OXT  sing N N 393 
VAL CB  CG1  sing N N 394 
VAL CB  CG2  sing N N 395 
VAL CB  HB   sing N N 396 
VAL CG1 HG11 sing N N 397 
VAL CG1 HG12 sing N N 398 
VAL CG1 HG13 sing N N 399 
VAL CG2 HG21 sing N N 400 
VAL CG2 HG22 sing N N 401 
VAL CG2 HG23 sing N N 402 
VAL OXT HXT  sing N N 403 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)' 'United States' 'R01 AI146779' 1 
'National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)' 'United States' 'P01 AI089618' 2 
# 
loop_
_pdbx_initial_refinement_model.id 
_pdbx_initial_refinement_model.entity_id_list 
_pdbx_initial_refinement_model.type 
_pdbx_initial_refinement_model.source_name 
_pdbx_initial_refinement_model.accession_code 
_pdbx_initial_refinement_model.details 
1 ? 'experimental model' PDB 4HKX ? 
2 ? 'experimental model' PDB 9AZR ? 
# 
_space_group.name_H-M_alt     'P 21 21 2' 
_space_group.name_Hall        'P 2 2ab' 
_space_group.IT_number        18 
_space_group.crystal_system   orthorhombic 
_space_group.id               1 
# 
_atom_sites.entry_id                    9AZV 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.013110 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.010699 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.009187 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 6.96715 ?       ? ? 11.43723 ?        ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 7.96527 ?       ? ? 9.05267  ?        ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . GLN A 1 1   ? 1.82149  -7.27291  25.47175  1.000 76.76457  ? 1   GLN H N   1 
ATOM   2    C CA  . GLN A 1 1   ? 2.32961  -6.27742  24.53582  1.000 109.98724 ? 1   GLN H CA  1 
ATOM   3    C C   . GLN A 1 1   ? 3.85808  -6.30815  24.53219  1.000 101.73025 ? 1   GLN H C   1 
ATOM   4    O O   . GLN A 1 1   ? 4.47318  -6.80183  25.47822  1.000 103.74412 ? 1   GLN H O   1 
ATOM   5    C CB  . GLN A 1 1   ? 1.80389  -4.88268  24.90089  1.000 111.02503 ? 1   GLN H CB  1 
ATOM   6    C CG  . GLN A 1 1   ? 2.15064  -3.78108  23.90593  1.000 98.20691  ? 1   GLN H CG  1 
ATOM   7    C CD  . GLN A 1 1   ? 0.93967  -2.97195  23.48256  1.000 125.56748 ? 1   GLN H CD  1 
ATOM   8    O OE1 . GLN A 1 1   ? -0.18600 -3.25710  23.89209  1.000 141.83033 ? 1   GLN H OE1 1 
ATOM   9    N NE2 . GLN A 1 1   ? 1.16495  -1.95753  22.65569  1.000 126.29602 ? 1   GLN H NE2 1 
ATOM   10   N N   . VAL A 1 2   ? 4.46214  -5.79600  23.45577  1.000 95.41774  ? 2   VAL H N   1 
ATOM   11   C CA  . VAL A 1 2   ? 5.91575  -5.77620  23.34479  1.000 84.88382  ? 2   VAL H CA  1 
ATOM   12   C C   . VAL A 1 2   ? 6.50785  -4.97543  24.49382  1.000 91.51225  ? 2   VAL H C   1 
ATOM   13   O O   . VAL A 1 2   ? 6.12039  -3.82619  24.74024  1.000 101.58980 ? 2   VAL H O   1 
ATOM   14   C CB  . VAL A 1 2   ? 6.33818  -5.19655  21.98694  1.000 84.18151  ? 2   VAL H CB  1 
ATOM   15   C CG1 . VAL A 1 2   ? 7.85396  -5.10668  21.89622  1.000 84.97231  ? 2   VAL H CG1 1 
ATOM   16   C CG2 . VAL A 1 2   ? 5.77640  -6.03729  20.85131  1.000 90.02634  ? 2   VAL H CG2 1 
ATOM   17   N N   . GLN A 1 3   ? 7.45456  -5.58325  25.20525  1.000 84.41768  ? 3   GLN H N   1 
ATOM   18   C CA  . GLN A 1 3   ? 8.10022  -4.93193  26.33393  1.000 77.76120  ? 3   GLN H CA  1 
ATOM   19   C C   . GLN A 1 3   ? 9.48936  -5.52146  26.52302  1.000 76.33533  ? 3   GLN H C   1 
ATOM   20   O O   . GLN A 1 3   ? 9.79442  -6.61468  26.03933  1.000 73.73661  ? 3   GLN H O   1 
ATOM   21   C CB  . GLN A 1 3   ? 7.27773  -5.08427  27.61915  1.000 91.67477  ? 3   GLN H CB  1 
ATOM   22   C CG  . GLN A 1 3   ? 7.31132  -6.48486  28.20995  1.000 85.21030  ? 3   GLN H CG  1 
ATOM   23   C CD  . GLN A 1 3   ? 6.11404  -6.77553  29.09232  1.000 101.07366 ? 3   GLN H CD  1 
ATOM   24   O OE1 . GLN A 1 3   ? 5.34617  -5.87582  29.43347  1.000 102.16086 ? 3   GLN H OE1 1 
ATOM   25   N NE2 . GLN A 1 3   ? 5.94740  -8.03909  29.46552  1.000 110.06508 ? 3   GLN H NE2 1 
ATOM   26   N N   . LEU A 1 4   ? 10.33198 -4.77616  27.23529  1.000 81.36432  ? 4   LEU H N   1 
ATOM   27   C CA  . LEU A 1 4   ? 11.67324 -5.22078  27.59498  1.000 81.46164  ? 4   LEU H CA  1 
ATOM   28   C C   . LEU A 1 4   ? 11.83893 -5.08638  29.10055  1.000 89.58244  ? 4   LEU H C   1 
ATOM   29   O O   . LEU A 1 4   ? 11.77788 -3.97479  29.63620  1.000 98.71052  ? 4   LEU H O   1 
ATOM   30   C CB  . LEU A 1 4   ? 12.74573 -4.41056  26.85968  1.000 71.01734  ? 4   LEU H CB  1 
ATOM   31   C CG  . LEU A 1 4   ? 12.57306 -4.24120  25.34898  1.000 75.21063  ? 4   LEU H CG  1 
ATOM   32   C CD1 . LEU A 1 4   ? 13.65715 -3.33903  24.77952  1.000 61.68776  ? 4   LEU H CD1 1 
ATOM   33   C CD2 . LEU A 1 4   ? 12.58792 -5.59555  24.65963  1.000 68.51663  ? 4   LEU H CD2 1 
ATOM   34   N N   . VAL A 1 5   ? 12.04629 -6.21137  29.77851  1.000 77.47291  ? 5   VAL H N   1 
ATOM   35   C CA  . VAL A 1 5   ? 12.24230 -6.23672  31.22344  1.000 76.48711  ? 5   VAL H CA  1 
ATOM   36   C C   . VAL A 1 5   ? 13.73065 -6.40077  31.50033  1.000 75.11384  ? 5   VAL H C   1 
ATOM   37   O O   . VAL A 1 5   ? 14.35989 -7.35708  31.03110  1.000 70.98741  ? 5   VAL H O   1 
ATOM   38   C CB  . VAL A 1 5   ? 11.41981 -7.35354  31.88630  1.000 73.41542  ? 5   VAL H CB  1 
ATOM   39   C CG1 . VAL A 1 5   ? 9.97459  -6.91458  32.04951  1.000 88.04181  ? 5   VAL H CG1 1 
ATOM   40   C CG2 . VAL A 1 5   ? 11.48595 -8.62825  31.06243  1.000 93.99034  ? 5   VAL H CG2 1 
ATOM   41   N N   . GLN A 1 6   ? 14.29371 -5.46583  32.25653  1.000 77.74510  ? 6   GLN H N   1 
ATOM   42   C CA  . GLN A 1 6   ? 15.71848 -5.43645  32.54501  1.000 78.87940  ? 6   GLN H CA  1 
ATOM   43   C C   . GLN A 1 6   ? 16.01183 -6.10737  33.88321  1.000 81.25266  ? 6   GLN H C   1 
ATOM   44   O O   . GLN A 1 6   ? 15.11067 -6.46715  34.64413  1.000 70.98219  ? 6   GLN H O   1 
ATOM   45   C CB  . GLN A 1 6   ? 16.23043 -3.99310  32.54516  1.000 73.99827  ? 6   GLN H CB  1 
ATOM   46   C CG  . GLN A 1 6   ? 15.89580 -3.22447  31.27928  1.000 71.55273  ? 6   GLN H CG  1 
ATOM   47   C CD  . GLN A 1 6   ? 16.71141 -1.95601  31.13079  1.000 82.60571  ? 6   GLN H CD  1 
ATOM   48   O OE1 . GLN A 1 6   ? 16.20007 -0.92282  30.69770  1.000 76.01029  ? 6   GLN H OE1 1 
ATOM   49   N NE2 . GLN A 1 6   ? 17.98814 -2.02760  31.48984  1.000 75.95739  ? 6   GLN H NE2 1 
ATOM   50   N N   . SER A 1 7   ? 17.30232 -6.27134  34.16269  1.000 75.49253  ? 7   SER H N   1 
ATOM   51   C CA  . SER A 1 7   ? 17.73419 -6.87141  35.41363  1.000 75.30938  ? 7   SER H CA  1 
ATOM   52   C C   . SER A 1 7   ? 17.53673 -5.89257  36.57149  1.000 88.53553  ? 7   SER H C   1 
ATOM   53   O O   . SER A 1 7   ? 17.25973 -4.70429  36.38335  1.000 94.25016  ? 7   SER H O   1 
ATOM   54   C CB  . SER A 1 7   ? 19.19644 -7.30591  35.32052  1.000 77.25501  ? 7   SER H CB  1 
ATOM   55   O OG  . SER A 1 7   ? 20.05407 -6.18597  35.18836  1.000 92.24080  ? 7   SER H OG  1 
ATOM   56   N N   . GLY A 1 8   ? 17.68457 -6.41134  37.78932  1.000 77.67375  ? 8   GLY H N   1 
ATOM   57   C CA  . GLY A 1 8   ? 17.48425 -5.61830  38.98173  1.000 74.76737  ? 8   GLY H CA  1 
ATOM   58   C C   . GLY A 1 8   ? 18.65328 -4.69905  39.28134  1.000 80.06235  ? 8   GLY H C   1 
ATOM   59   O O   . GLY A 1 8   ? 19.63894 -4.62297  38.54799  1.000 87.08301  ? 8   GLY H O   1 
ATOM   60   N N   . ALA A 1 9   ? 18.52638 -3.98238  40.39658  1.000 69.88368  ? 9   ALA H N   1 
ATOM   61   C CA  . ALA A 1 9   ? 19.55353 -3.03308  40.80236  1.000 79.22216  ? 9   ALA H CA  1 
ATOM   62   C C   . ALA A 1 9   ? 20.85614 -3.75413  41.13164  1.000 79.60788  ? 9   ALA H C   1 
ATOM   63   O O   . ALA A 1 9   ? 20.86116 -4.87372  41.65059  1.000 82.15702  ? 9   ALA H O   1 
ATOM   64   C CB  . ALA A 1 9   ? 19.08141 -2.22098  42.00868  1.000 84.88037  ? 9   ALA H CB  1 
ATOM   65   N N   . GLU A 1 10  ? 21.97252 -3.09708  40.82132  1.000 84.42193  ? 10  GLU H N   1 
ATOM   66   C CA  . GLU A 1 10  ? 23.29734 -3.67091  41.00590  1.000 80.01920  ? 10  GLU H CA  1 
ATOM   67   C C   . GLU A 1 10  ? 24.19938 -2.69709  41.74895  1.000 82.53350  ? 10  GLU H C   1 
ATOM   68   O O   . GLU A 1 10  ? 24.17653 -1.48994  41.48974  1.000 78.44288  ? 10  GLU H O   1 
ATOM   69   C CB  . GLU A 1 10  ? 23.93583 -4.03836  39.66088  1.000 77.57150  ? 10  GLU H CB  1 
ATOM   70   C CG  . GLU A 1 10  ? 23.74434 -5.48912  39.26434  1.000 93.95289  ? 10  GLU H CG  1 
ATOM   71   C CD  . GLU A 1 10  ? 24.77811 -5.96413  38.26345  1.000 104.54675 ? 10  GLU H CD  1 
ATOM   72   O OE1 . GLU A 1 10  ? 25.82103 -5.29272  38.11815  1.000 105.99776 ? 10  GLU H OE1 1 
ATOM   73   O OE2 . GLU A 1 10  ? 24.55113 -7.01481  37.62815  1.000 93.95303  ? 10  GLU H OE2 1 
ATOM   74   N N   . VAL A 1 11  ? 24.99016 -3.23322  42.67649  1.000 79.61413  ? 11  VAL H N   1 
ATOM   75   C CA  . VAL A 1 11  ? 26.02565 -2.48554  43.37977  1.000 75.25793  ? 11  VAL H CA  1 
ATOM   76   C C   . VAL A 1 11  ? 27.33984 -3.23262  43.20239  1.000 82.12723  ? 11  VAL H C   1 
ATOM   77   O O   . VAL A 1 11  ? 27.41589 -4.43429  43.48180  1.000 99.36379  ? 11  VAL H O   1 
ATOM   78   C CB  . VAL A 1 11  ? 25.69862 -2.31051  44.87555  1.000 73.37219  ? 11  VAL H CB  1 
ATOM   79   C CG1 . VAL A 1 11  ? 26.70223 -1.37549  45.53095  1.000 64.18252  ? 11  VAL H CG1 1 
ATOM   80   C CG2 . VAL A 1 11  ? 24.28042 -1.78980  45.05620  1.000 72.04108  ? 11  VAL H CG2 1 
ATOM   81   N N   . ARG A 1 12  ? 28.36989 -2.52678  42.73945  1.000 67.28943  ? 12  ARG H N   1 
ATOM   82   C CA  . ARG A 1 12  ? 29.64932 -3.14675  42.42585  1.000 74.88374  ? 12  ARG H CA  1 
ATOM   83   C C   . ARG A 1 12  ? 30.78283 -2.27651  42.94537  1.000 71.81567  ? 12  ARG H C   1 
ATOM   84   O O   . ARG A 1 12  ? 30.62581 -1.07383  43.14340  1.000 73.89748  ? 12  ARG H O   1 
ATOM   85   C CB  . ARG A 1 12  ? 29.81627 -3.36191  40.91618  1.000 78.16309  ? 12  ARG H CB  1 
ATOM   86   C CG  . ARG A 1 12  ? 28.92438 -4.43982  40.33664  1.000 84.51806  ? 12  ARG H CG  1 
ATOM   87   C CD  . ARG A 1 12  ? 29.33245 -5.81460  40.83021  1.000 90.09709  ? 12  ARG H CD  1 
ATOM   88   N NE  . ARG A 1 12  ? 28.95312 -6.85693  39.88500  1.000 99.70542  ? 12  ARG H NE  1 
ATOM   89   C CZ  . ARG A 1 12  ? 27.78589 -7.48534  39.89368  1.000 106.50563 ? 12  ARG H CZ  1 
ATOM   90   N NH1 . ARG A 1 12  ? 26.85572 -7.20283  40.79120  1.000 97.54509  ? 12  ARG H NH1 1 
ATOM   91   N NH2 . ARG A 1 12  ? 27.54466 -8.41842  38.97710  1.000 100.88668 ? 12  ARG H NH2 1 
ATOM   92   N N   . LYS A 1 13  ? 31.92502 -2.89772  43.17250  1.000 81.84413  ? 13  LYS H N   1 
ATOM   93   C CA  . LYS A 1 13  ? 33.12688 -2.14865  43.50132  1.000 89.17928  ? 13  LYS H CA  1 
ATOM   94   C C   . LYS A 1 13  ? 33.84845 -1.73142  42.22729  1.000 77.04917  ? 13  LYS H C   1 
ATOM   95   O O   . LYS A 1 13  ? 33.60302 -2.29112  41.15499  1.000 77.29607  ? 13  LYS H O   1 
ATOM   96   C CB  . LYS A 1 13  ? 34.04190 -2.99087  44.38856  1.000 79.98962  ? 13  LYS H CB  1 
ATOM   97   C CG  . LYS A 1 13  ? 33.30896 -3.70606  45.51039  1.000 69.00050  ? 13  LYS H CG  1 
ATOM   98   C CD  . LYS A 1 13  ? 33.38633 -2.90599  46.80206  1.000 95.21084  ? 13  LYS H CD  1 
ATOM   99   C CE  . LYS A 1 13  ? 32.31201 -3.33322  47.78848  1.000 92.17712  ? 13  LYS H CE  1 
ATOM   100  N NZ  . LYS A 1 13  ? 31.84012 -2.18787  48.61686  1.000 90.46433  ? 13  LYS H NZ  1 
ATOM   101  N N   . PRO A 1 14  ? 34.72503 -0.72730  42.29752  1.000 79.26591  ? 14  PRO H N   1 
ATOM   102  C CA  . PRO A 1 14  ? 35.47045 -0.32669  41.09776  1.000 78.55243  ? 14  PRO H CA  1 
ATOM   103  C C   . PRO A 1 14  ? 36.28405 -1.48500  40.53923  1.000 87.20342  ? 14  PRO H C   1 
ATOM   104  O O   . PRO A 1 14  ? 36.87535 -2.27129  41.28233  1.000 83.73415  ? 14  PRO H O   1 
ATOM   105  C CB  . PRO A 1 14  ? 36.37333 0.80841   41.60044  1.000 73.12110  ? 14  PRO H CB  1 
ATOM   106  C CG  . PRO A 1 14  ? 36.35220 0.69273   43.10111  1.000 87.20928  ? 14  PRO H CG  1 
ATOM   107  C CD  . PRO A 1 14  ? 34.98717 0.18661   43.41989  1.000 84.98157  ? 14  PRO H CD  1 
ATOM   108  N N   . GLY A 1 15  ? 36.30668 -1.58261  39.21151  1.000 73.55482  ? 15  GLY H N   1 
ATOM   109  C CA  . GLY A 1 15  ? 36.97619 -2.67072  38.53385  1.000 72.24253  ? 15  GLY H CA  1 
ATOM   110  C C   . GLY A 1 15  ? 36.17044 -3.94442  38.40271  1.000 74.99290  ? 15  GLY H C   1 
ATOM   111  O O   . GLY A 1 15  ? 36.66970 -4.91345  37.81765  1.000 96.12778  ? 15  GLY H O   1 
ATOM   112  N N   . ALA A 1 16  ? 34.94469 -3.97978  38.91675  1.000 69.86966  ? 16  ALA H N   1 
ATOM   113  C CA  . ALA A 1 16  ? 34.13614 -5.18419  38.83806  1.000 92.43954  ? 16  ALA H CA  1 
ATOM   114  C C   . ALA A 1 16  ? 33.48140 -5.30492  37.46388  1.000 96.79041  ? 16  ALA H C   1 
ATOM   115  O O   . ALA A 1 16  ? 33.51064 -4.38514  36.64173  1.000 83.95697  ? 16  ALA H O   1 
ATOM   116  C CB  . ALA A 1 16  ? 33.07359 -5.19395  39.93577  1.000 94.75945  ? 16  ALA H CB  1 
ATOM   117  N N   . SER A 1 17  ? 32.88283 -6.46761  37.22103  1.000 115.47764 ? 17  SER H N   1 
ATOM   118  C CA  . SER A 1 17  ? 32.19225 -6.75605  35.96965  1.000 104.73075 ? 17  SER H CA  1 
ATOM   119  C C   . SER A 1 17  ? 30.70335 -6.49622  36.16994  1.000 103.73502 ? 17  SER H C   1 
ATOM   120  O O   . SER A 1 17  ? 30.02770 -7.23898  36.89008  1.000 105.80094 ? 17  SER H O   1 
ATOM   121  C CB  . SER A 1 17  ? 32.44650 -8.19596  35.52906  1.000 110.80166 ? 17  SER H CB  1 
ATOM   122  O OG  . SER A 1 17  ? 33.73036 -8.33114  34.94546  1.000 116.49868 ? 17  SER H OG  1 
ATOM   123  N N   . VAL A 1 18  ? 30.19730 -5.44222  35.53701  1.000 85.75473  ? 18  VAL H N   1 
ATOM   124  C CA  . VAL A 1 18  ? 28.78813 -5.07688  35.61109  1.000 89.38486  ? 18  VAL H CA  1 
ATOM   125  C C   . VAL A 1 18  ? 28.08208 -5.67339  34.40219  1.000 84.29209  ? 18  VAL H C   1 
ATOM   126  O O   . VAL A 1 18  ? 28.42470 -5.35864  33.25660  1.000 91.80484  ? 18  VAL H O   1 
ATOM   127  C CB  . VAL A 1 18  ? 28.60636 -3.55246  35.66087  1.000 85.35614  ? 18  VAL H CB  1 
ATOM   128  C CG1 . VAL A 1 18  ? 27.13322 -3.19099  35.53743  1.000 91.75343  ? 18  VAL H CG1 1 
ATOM   129  C CG2 . VAL A 1 18  ? 29.19816 -2.99012  36.94406  1.000 97.96701  ? 18  VAL H CG2 1 
ATOM   130  N N   . LYS A 1 19  ? 27.09743 -6.53288  34.65287  1.000 79.56583  ? 19  LYS H N   1 
ATOM   131  C CA  . LYS A 1 19  ? 26.34801 -7.20611  33.60086  1.000 74.66113  ? 19  LYS H CA  1 
ATOM   132  C C   . LYS A 1 19  ? 24.86715 -6.89347  33.75652  1.000 77.81223  ? 19  LYS H C   1 
ATOM   133  O O   . LYS A 1 19  ? 24.29913 -7.08140  34.83705  1.000 91.43614  ? 19  LYS H O   1 
ATOM   134  C CB  . LYS A 1 19  ? 26.58129 -8.71920  33.64170  1.000 74.13278  ? 19  LYS H CB  1 
ATOM   135  C CG  . LYS A 1 19  ? 26.12047 -9.45320  32.39163  1.000 101.72085 ? 19  LYS H CG  1 
ATOM   136  C CD  . LYS A 1 19  ? 26.40672 -10.94728 32.47414  1.000 108.39338 ? 19  LYS H CD  1 
ATOM   137  C CE  . LYS A 1 19  ? 27.84340 -11.27231 32.08348  1.000 102.74930 ? 19  LYS H CE  1 
ATOM   138  N NZ  . LYS A 1 19  ? 28.81716 -11.00749 33.18088  1.000 135.17750 ? 19  LYS H NZ  1 
ATOM   139  N N   . VAL A 1 20  ? 24.24619 -6.42358  32.67772  1.000 77.12988  ? 20  VAL H N   1 
ATOM   140  C CA  . VAL A 1 20  ? 22.83774 -6.04725  32.66942  1.000 70.66374  ? 20  VAL H CA  1 
ATOM   141  C C   . VAL A 1 20  ? 22.12408 -6.88458  31.61850  1.000 71.00744  ? 20  VAL H C   1 
ATOM   142  O O   . VAL A 1 20  ? 22.59513 -6.99428  30.48060  1.000 86.90430  ? 20  VAL H O   1 
ATOM   143  C CB  . VAL A 1 20  ? 22.65146 -4.54446  32.39040  1.000 82.49083  ? 20  VAL H CB  1 
ATOM   144  C CG1 . VAL A 1 20  ? 21.17901 -4.17329  32.45106  1.000 91.27607  ? 20  VAL H CG1 1 
ATOM   145  C CG2 . VAL A 1 20  ? 23.45734 -3.71509  33.37982  1.000 59.77084  ? 20  VAL H CG2 1 
ATOM   146  N N   . SER A 1 21  ? 20.99737 -7.47501  32.00027  1.000 73.75038  ? 21  SER H N   1 
ATOM   147  C CA  . SER A 1 21  ? 20.19968 -8.29866  31.10553  1.000 84.42925  ? 21  SER H CA  1 
ATOM   148  C C   . SER A 1 21  ? 19.01165 -7.50879  30.56813  1.000 85.32085  ? 21  SER H C   1 
ATOM   149  O O   . SER A 1 21  ? 18.58448 -6.50693  31.14724  1.000 82.20799  ? 21  SER H O   1 
ATOM   150  C CB  . SER A 1 21  ? 19.70954 -9.56039  31.82159  1.000 85.75998  ? 21  SER H CB  1 
ATOM   151  O OG  . SER A 1 21  ? 18.47661 -9.32668  32.48060  1.000 79.56013  ? 21  SER H OG  1 
ATOM   152  N N   . CYS A 1 22  ? 18.47974 -7.97843  29.43887  1.000 77.66136  ? 22  CYS H N   1 
ATOM   153  C CA  . CYS A 1 22  ? 17.33023 -7.33417  28.80457  1.000 82.16754  ? 22  CYS H CA  1 
ATOM   154  C C   . CYS A 1 22  ? 16.52213 -8.42133  28.10074  1.000 84.04017  ? 22  CYS H C   1 
ATOM   155  O O   . CYS A 1 22  ? 16.87009 -8.83821  26.99189  1.000 76.48369  ? 22  CYS H O   1 
ATOM   156  C CB  . CYS A 1 22  ? 17.77349 -6.24588  27.83577  1.000 78.14355  ? 22  CYS H CB  1 
ATOM   157  S SG  . CYS A 1 22  ? 16.41916 -5.34050  27.04739  1.000 82.29244  ? 22  CYS H SG  1 
ATOM   158  N N   . LYS A 1 23  ? 15.45379 -8.87280  28.75238  1.000 85.96746  ? 23  LYS H N   1 
ATOM   159  C CA  . LYS A 1 23  ? 14.57796 -9.88541  28.18092  1.000 83.65393  ? 23  LYS H CA  1 
ATOM   160  C C   . LYS A 1 23  ? 13.54143 -9.23667  27.27208  1.000 89.98790  ? 23  LYS H C   1 
ATOM   161  O O   . LYS A 1 23  ? 12.99593 -8.17535  27.58667  1.000 96.03195  ? 23  LYS H O   1 
ATOM   162  C CB  . LYS A 1 23  ? 13.88350 -10.67359 29.29228  1.000 101.08301 ? 23  LYS H CB  1 
ATOM   163  C CG  . LYS A 1 23  ? 13.02771 -11.83085 28.80660  1.000 108.79762 ? 23  LYS H CG  1 
ATOM   164  C CD  . LYS A 1 23  ? 13.79814 -13.13791 28.84737  1.000 93.33030  ? 23  LYS H CD  1 
ATOM   165  C CE  . LYS A 1 23  ? 12.86473 -14.32291 29.03168  1.000 105.62773 ? 23  LYS H CE  1 
ATOM   166  N NZ  . LYS A 1 23  ? 11.78286 -14.33840 28.00859  1.000 121.91338 ? 23  LYS H NZ  1 
ATOM   167  N N   . ALA A 1 24  ? 13.27017 -9.88189  26.14120  1.000 85.86558  ? 24  ALA H N   1 
ATOM   168  C CA  . ALA A 1 24  ? 12.32955 -9.37723  25.15174  1.000 82.06333  ? 24  ALA H CA  1 
ATOM   169  C C   . ALA A 1 24  ? 11.12648 -10.30492 25.04957  1.000 84.06172  ? 24  ALA H C   1 
ATOM   170  O O   . ALA A 1 24  ? 11.26892 -11.53074 25.10065  1.000 89.20321  ? 24  ALA H O   1 
ATOM   171  C CB  . ALA A 1 24  ? 12.99731 -9.23629  23.78160  1.000 82.42652  ? 24  ALA H CB  1 
ATOM   172  N N   . SER A 1 25  ? 9.94186  -9.71331  24.90594  1.000 88.09615  ? 25  SER H N   1 
ATOM   173  C CA  . SER A 1 25  ? 8.71210  -10.48113 24.77805  1.000 89.91454  ? 25  SER H CA  1 
ATOM   174  C C   . SER A 1 25  ? 7.70835  -9.68550  23.95683  1.000 89.39636  ? 25  SER H C   1 
ATOM   175  O O   . SER A 1 25  ? 7.80517  -8.46143  23.83544  1.000 85.83751  ? 25  SER H O   1 
ATOM   176  C CB  . SER A 1 25  ? 8.12129  -10.83453 26.14862  1.000 92.22241  ? 25  SER H CB  1 
ATOM   177  O OG  . SER A 1 25  ? 8.10758  -9.70584  27.00539  1.000 102.32935 ? 25  SER H OG  1 
ATOM   178  N N   . GLY A 1 26  ? 6.73602  -10.40143 23.39388  1.000 94.41850  ? 26  GLY H N   1 
ATOM   179  C CA  . GLY A 1 26  ? 5.69076  -9.79358  22.59861  1.000 102.32244 ? 26  GLY H CA  1 
ATOM   180  C C   . GLY A 1 26  ? 5.99835  -9.64035  21.12472  1.000 98.83167  ? 26  GLY H C   1 
ATOM   181  O O   . GLY A 1 26  ? 5.11806  -9.20927  20.36826  1.000 90.95883  ? 26  GLY H O   1 
ATOM   182  N N   . TYR A 1 27  ? 7.20933  -9.97874  20.68955  1.000 77.29400  ? 27  TYR H N   1 
ATOM   183  C CA  . TYR A 1 27  ? 7.58697  -9.82901  19.29166  1.000 84.99137  ? 27  TYR H CA  1 
ATOM   184  C C   . TYR A 1 27  ? 8.70604  -10.81201 18.98427  1.000 90.12125  ? 27  TYR H C   1 
ATOM   185  O O   . TYR A 1 27  ? 9.33238  -11.36841 19.88999  1.000 91.72246  ? 27  TYR H O   1 
ATOM   186  C CB  . TYR A 1 27  ? 8.01967  -8.39164  18.97937  1.000 86.93612  ? 27  TYR H CB  1 
ATOM   187  C CG  . TYR A 1 27  ? 9.42016  -8.05430  19.44023  1.000 76.34829  ? 27  TYR H CG  1 
ATOM   188  C CD1 . TYR A 1 27  ? 9.72644  -7.95959  20.79090  1.000 74.91988  ? 27  TYR H CD1 1 
ATOM   189  C CD2 . TYR A 1 27  ? 10.43259 -7.81463  18.52224  1.000 86.43782  ? 27  TYR H CD2 1 
ATOM   190  C CE1 . TYR A 1 27  ? 11.00586 -7.64903  21.21328  1.000 74.72957  ? 27  TYR H CE1 1 
ATOM   191  C CE2 . TYR A 1 27  ? 11.71417 -7.50390  18.93452  1.000 87.02610  ? 27  TYR H CE2 1 
ATOM   192  C CZ  . TYR A 1 27  ? 11.99526 -7.42160  20.28042  1.000 67.30132  ? 27  TYR H CZ  1 
ATOM   193  O OH  . TYR A 1 27  ? 13.27053 -7.11028  20.69249  1.000 63.78600  ? 27  TYR H OH  1 
ATOM   194  N N   . THR A 1 28  ? 8.94441  -11.02410 17.69133  1.000 83.94043  ? 28  THR H N   1 
ATOM   195  C CA  . THR A 1 28  ? 10.00755 -11.92491 17.26192  1.000 89.23703  ? 28  THR H CA  1 
ATOM   196  C C   . THR A 1 28  ? 11.36069 -11.34250 17.65420  1.000 88.23732  ? 28  THR H C   1 
ATOM   197  O O   . THR A 1 28  ? 11.71386 -10.23521 17.23587  1.000 89.07264  ? 28  THR H O   1 
ATOM   198  C CB  . THR A 1 28  ? 9.93441  -12.15739 15.75508  1.000 89.86558  ? 28  THR H CB  1 
ATOM   199  O OG1 . THR A 1 28  ? 8.60401  -12.55062 15.39493  1.000 76.01400  ? 28  THR H OG1 1 
ATOM   200  C CG2 . THR A 1 28  ? 10.90938 -13.24855 15.33732  1.000 77.65266  ? 28  THR H CG2 1 
ATOM   201  N N   . PHE A 1 29  ? 12.12199 -12.10209 18.44543  1.000 74.74557  ? 29  PHE H N   1 
ATOM   202  C CA  . PHE A 1 29  ? 13.32654 -11.56567 19.07324  1.000 82.82692  ? 29  PHE H CA  1 
ATOM   203  C C   . PHE A 1 29  ? 14.36963 -11.15131 18.04150  1.000 88.27202  ? 29  PHE H C   1 
ATOM   204  O O   . PHE A 1 29  ? 15.04355 -10.12770 18.20724  1.000 91.64667  ? 29  PHE H O   1 
ATOM   205  C CB  . PHE A 1 29  ? 13.90658 -12.59857 20.03859  1.000 85.88039  ? 29  PHE H CB  1 
ATOM   206  C CG  . PHE A 1 29  ? 15.20806 -12.18657 20.66086  1.000 79.99580  ? 29  PHE H CG  1 
ATOM   207  C CD1 . PHE A 1 29  ? 15.31619 -10.98787 21.34652  1.000 83.99193  ? 29  PHE H CD1 1 
ATOM   208  C CD2 . PHE A 1 29  ? 16.32329 -13.00207 20.56457  1.000 80.24035  ? 29  PHE H CD2 1 
ATOM   209  C CE1 . PHE A 1 29  ? 16.51387 -10.60940 21.92194  1.000 79.25204  ? 29  PHE H CE1 1 
ATOM   210  C CE2 . PHE A 1 29  ? 17.52224 -12.63028 21.13894  1.000 89.06186  ? 29  PHE H CE2 1 
ATOM   211  C CZ  . PHE A 1 29  ? 17.61771 -11.43291 21.81758  1.000 85.22742  ? 29  PHE H CZ  1 
ATOM   212  N N   . THR A 1 30  ? 14.51589 -11.92741 16.96927  1.000 73.78621  ? 30  THR H N   1 
ATOM   213  C CA  . THR A 1 30  ? 15.56802 -11.71297 15.98578  1.000 81.99715  ? 30  THR H CA  1 
ATOM   214  C C   . THR A 1 30  ? 15.17405 -10.71769 14.89799  1.000 92.27976  ? 30  THR H C   1 
ATOM   215  O O   . THR A 1 30  ? 15.72414 -10.77432 13.79266  1.000 93.44346  ? 30  THR H O   1 
ATOM   216  C CB  . THR A 1 30  ? 15.97305 -13.04501 15.35052  1.000 87.07463  ? 30  THR H CB  1 
ATOM   217  O OG1 . THR A 1 30  ? 14.80033 -13.74732 14.92041  1.000 87.02845  ? 30  THR H OG1 1 
ATOM   218  C CG2 . THR A 1 30  ? 16.73140 -13.90222 16.35177  1.000 82.39746  ? 30  THR H CG2 1 
ATOM   219  N N   . ASP A 1 31  ? 14.23817 -9.81204  15.18061  1.000 93.00259  ? 31  ASP H N   1 
ATOM   220  C CA  . ASP A 1 31  ? 13.75615 -8.87872  14.16610  1.000 90.69403  ? 31  ASP H CA  1 
ATOM   221  C C   . ASP A 1 31  ? 14.57742 -7.59095  14.12025  1.000 84.97360  ? 31  ASP H C   1 
ATOM   222  O O   . ASP A 1 31  ? 15.14458 -7.24796  13.07829  1.000 79.27507  ? 31  ASP H O   1 
ATOM   223  C CB  . ASP A 1 31  ? 12.27724 -8.55775  14.41007  1.000 98.43752  ? 31  ASP H CB  1 
ATOM   224  C CG  . ASP A 1 31  ? 11.35215 -9.62109  13.85504  1.000 96.99963  ? 31  ASP H CG  1 
ATOM   225  O OD1 . ASP A 1 31  ? 11.85589 -10.67052 13.40220  1.000 92.22179  ? 31  ASP H OD1 1 
ATOM   226  O OD2 . ASP A 1 31  ? 10.12157 -9.40676  13.86826  1.000 100.42701 ? 31  ASP H OD2 1 
ATOM   227  N N   . ASN A 1 32  ? 14.65040 -6.87130  15.23723  1.000 84.63433  ? 32  ASN H N   1 
ATOM   228  C CA  . ASN A 1 32  ? 15.20553 -5.52686  15.25992  1.000 91.46025  ? 32  ASN H CA  1 
ATOM   229  C C   . ASN A 1 32  ? 16.42614 -5.45025  16.16827  1.000 85.02200  ? 32  ASN H C   1 
ATOM   230  O O   . ASN A 1 32  ? 16.68062 -6.33802  16.98678  1.000 70.85037  ? 32  ASN H O   1 
ATOM   231  C CB  . ASN A 1 32  ? 14.15701 -4.50723  15.72331  1.000 93.79018  ? 32  ASN H CB  1 
ATOM   232  C CG  . ASN A 1 32  ? 12.75555 -4.86639  15.27241  1.000 97.23262  ? 32  ASN H CG  1 
ATOM   233  O OD1 . ASN A 1 32  ? 12.40505 -4.70060  14.10373  1.000 110.44407 ? 32  ASN H OD1 1 
ATOM   234  N ND2 . ASN A 1 32  ? 11.94501 -5.36346  16.19971  1.000 76.38135  ? 32  ASN H ND2 1 
ATOM   235  N N   . TYR A 1 33  ? 17.17759 -4.36215  16.01106  1.000 87.69704  ? 33  TYR H N   1 
ATOM   236  C CA  . TYR A 1 33  ? 18.33679 -4.10604  16.85037  1.000 74.55655  ? 33  TYR H CA  1 
ATOM   237  C C   . TYR A 1 33  ? 17.90656 -3.78783  18.27931  1.000 83.17768  ? 33  TYR H C   1 
ATOM   238  O O   . TYR A 1 33  ? 16.76745 -3.39356  18.54507  1.000 80.70683  ? 33  TYR H O   1 
ATOM   239  C CB  . TYR A 1 33  ? 19.16348 -2.93543  16.30977  1.000 84.87752  ? 33  TYR H CB  1 
ATOM   240  C CG  . TYR A 1 33  ? 19.48945 -2.98455  14.83240  1.000 82.10502  ? 33  TYR H CG  1 
ATOM   241  C CD1 . TYR A 1 33  ? 18.57012 -2.56128  13.88098  1.000 68.51692  ? 33  TYR H CD1 1 
ATOM   242  C CD2 . TYR A 1 33  ? 20.72971 -3.42679  14.39207  1.000 75.01562  ? 33  TYR H CD2 1 
ATOM   243  C CE1 . TYR A 1 33  ? 18.87039 -2.59604  12.53324  1.000 89.52443  ? 33  TYR H CE1 1 
ATOM   244  C CE2 . TYR A 1 33  ? 21.03939 -3.46469  13.04674  1.000 69.93586  ? 33  TYR H CE2 1 
ATOM   245  C CZ  . TYR A 1 33  ? 20.10646 -3.04809  12.12152  1.000 92.68123  ? 33  TYR H CZ  1 
ATOM   246  O OH  . TYR A 1 33  ? 20.41012 -3.08366  10.77949  1.000 104.50326 ? 33  TYR H OH  1 
ATOM   247  N N   . ILE A 1 34  ? 18.84396 -3.96238  19.20649  1.000 89.34226  ? 34  ILE H N   1 
ATOM   248  C CA  . ILE A 1 34  ? 18.67210 -3.55955  20.59718  1.000 70.14991  ? 34  ILE H CA  1 
ATOM   249  C C   . ILE A 1 34  ? 19.76776 -2.55613  20.92442  1.000 74.99161  ? 34  ILE H C   1 
ATOM   250  O O   . ILE A 1 34  ? 20.95791 -2.86087  20.77907  1.000 74.69957  ? 34  ILE H O   1 
ATOM   251  C CB  . ILE A 1 34  ? 18.71973 -4.75850  21.55700  1.000 67.79077  ? 34  ILE H CB  1 
ATOM   252  C CG1 . ILE A 1 34  ? 17.73882 -5.84361  21.10730  1.000 74.71058  ? 34  ILE H CG1 1 
ATOM   253  C CG2 . ILE A 1 34  ? 18.41816 -4.31154  22.97966  1.000 79.30534  ? 34  ILE H CG2 1 
ATOM   254  C CD1 . ILE A 1 34  ? 16.29168 -5.53446  21.43083  1.000 65.18777  ? 34  ILE H CD1 1 
ATOM   255  N N   . HIS A 1 35  ? 19.36920 -1.36720  21.36502  1.000 81.45772  ? 35  HIS H N   1 
ATOM   256  C CA  . HIS A 1 35  ? 20.29947 -0.29916  21.69699  1.000 78.11511  ? 35  HIS H CA  1 
ATOM   257  C C   . HIS A 1 35  ? 20.41673 -0.14973  23.20892  1.000 78.79516  ? 35  HIS H C   1 
ATOM   258  O O   . HIS A 1 35  ? 19.48652 -0.46135  23.95640  1.000 68.48588  ? 35  HIS H O   1 
ATOM   259  C CB  . HIS A 1 35  ? 19.85251 1.02797   21.07852  1.000 79.99255  ? 35  HIS H CB  1 
ATOM   260  C CG  . HIS A 1 35  ? 19.88602 1.04159   19.58159  1.000 84.24127  ? 35  HIS H CG  1 
ATOM   261  N ND1 . HIS A 1 35  ? 20.75302 1.83715   18.86364  1.000 78.86228  ? 35  HIS H ND1 1 
ATOM   262  C CD2 . HIS A 1 35  ? 19.15625 0.36024   18.66683  1.000 85.30358  ? 35  HIS H CD2 1 
ATOM   263  C CE1 . HIS A 1 35  ? 20.55765 1.64358   17.57153  1.000 84.59979  ? 35  HIS H CE1 1 
ATOM   264  N NE2 . HIS A 1 35  ? 19.59395 0.75221   17.42499  1.000 89.07805  ? 35  HIS H NE2 1 
ATOM   265  N N   . TRP A 1 36  ? 21.57567 0.33177   23.65248  1.000 85.88817  ? 36  TRP H N   1 
ATOM   266  C CA  . TRP A 1 36  ? 21.85255 0.55805   25.06481  1.000 68.81084  ? 36  TRP H CA  1 
ATOM   267  C C   . TRP A 1 36  ? 22.26302 2.00794   25.27044  1.000 66.24361  ? 36  TRP H C   1 
ATOM   268  O O   . TRP A 1 36  ? 23.12419 2.52081   24.54838  1.000 81.29005  ? 36  TRP H O   1 
ATOM   269  C CB  . TRP A 1 36  ? 22.95708 -0.37409  25.57298  1.000 72.55007  ? 36  TRP H CB  1 
ATOM   270  C CG  . TRP A 1 36  ? 22.55196 -1.81262  25.65837  1.000 85.22354  ? 36  TRP H CG  1 
ATOM   271  C CD1 . TRP A 1 36  ? 22.59952 -2.73896  24.65777  1.000 85.57535  ? 36  TRP H CD1 1 
ATOM   272  C CD2 . TRP A 1 36  ? 22.03463 -2.49117  26.80934  1.000 80.44129  ? 36  TRP H CD2 1 
ATOM   273  N NE1 . TRP A 1 36  ? 22.14602 -3.95266  25.11477  1.000 86.15991  ? 36  TRP H NE1 1 
ATOM   274  C CE2 . TRP A 1 36  ? 21.79232 -3.82678  26.43257  1.000 82.19044  ? 36  TRP H CE2 1 
ATOM   275  C CE3 . TRP A 1 36  ? 21.75251 -2.09868  28.12146  1.000 81.37764  ? 36  TRP H CE3 1 
ATOM   276  C CZ2 . TRP A 1 36  ? 21.28153 -4.77166  27.31995  1.000 84.47814  ? 36  TRP H CZ2 1 
ATOM   277  C CZ3 . TRP A 1 36  ? 21.24581 -3.03833  29.00085  1.000 77.12073  ? 36  TRP H CZ3 1 
ATOM   278  C CH2 . TRP A 1 36  ? 21.01555 -4.35871  28.59640  1.000 80.36351  ? 36  TRP H CH2 1 
ATOM   279  N N   . VAL A 1 37  ? 21.64901 2.66449   26.25252  1.000 69.96639  ? 37  VAL H N   1 
ATOM   280  C CA  . VAL A 1 37  ? 21.98696 4.03687   26.60438  1.000 83.49963  ? 37  VAL H CA  1 
ATOM   281  C C   . VAL A 1 37  ? 22.23756 4.11436   28.10312  1.000 73.56963  ? 37  VAL H C   1 
ATOM   282  O O   . VAL A 1 37  ? 21.73174 3.30060   28.88310  1.000 61.12359  ? 37  VAL H O   1 
ATOM   283  C CB  . VAL A 1 37  ? 20.88788 5.04193   26.18501  1.000 74.58384  ? 37  VAL H CB  1 
ATOM   284  C CG1 . VAL A 1 37  ? 20.57006 4.90671   24.70239  1.000 79.80542  ? 37  VAL H CG1 1 
ATOM   285  C CG2 . VAL A 1 37  ? 19.63746 4.85148   27.02676  1.000 81.08057  ? 37  VAL H CG2 1 
ATOM   286  N N   . ARG A 1 38  ? 23.02832 5.10713   28.50257  1.000 76.20718  ? 38  ARG H N   1 
ATOM   287  C CA  . ARG A 1 38  ? 23.41440 5.30792   29.89198  1.000 63.19559  ? 38  ARG H CA  1 
ATOM   288  C C   . ARG A 1 38  ? 23.08337 6.73676   30.29276  1.000 70.67958  ? 38  ARG H C   1 
ATOM   289  O O   . ARG A 1 38  ? 23.40947 7.67901   29.56382  1.000 75.67119  ? 38  ARG H O   1 
ATOM   290  C CB  . ARG A 1 38  ? 24.90766 5.01856   30.08737  1.000 55.59073  ? 38  ARG H CB  1 
ATOM   291  C CG  . ARG A 1 38  ? 25.56691 5.79412   31.21197  1.000 74.82337  ? 38  ARG H CG  1 
ATOM   292  C CD  . ARG A 1 38  ? 26.96670 5.26647   31.48353  1.000 79.30493  ? 38  ARG H CD  1 
ATOM   293  N NE  . ARG A 1 38  ? 27.91805 6.33995   31.74520  1.000 87.90914  ? 38  ARG H NE  1 
ATOM   294  C CZ  . ARG A 1 38  ? 29.23088 6.17239   31.82944  1.000 94.60452  ? 38  ARG H CZ  1 
ATOM   295  N NH1 . ARG A 1 38  ? 29.78619 4.98032   31.68402  1.000 85.10026  ? 38  ARG H NH1 1 
ATOM   296  N NH2 . ARG A 1 38  ? 30.00617 7.22718   32.06590  1.000 91.63329  ? 38  ARG H NH2 1 
ATOM   297  N N   . GLN A 1 39  ? 22.43505 6.89683   31.44477  1.000 76.43787  ? 39  GLN H N   1 
ATOM   298  C CA  . GLN A 1 39  ? 22.00751 8.20459   31.93319  1.000 72.51362  ? 39  GLN H CA  1 
ATOM   299  C C   . GLN A 1 39  ? 22.57608 8.43242   33.32692  1.000 69.04270  ? 39  GLN H C   1 
ATOM   300  O O   . GLN A 1 39  ? 22.10165 7.83767   34.30102  1.000 72.54259  ? 39  GLN H O   1 
ATOM   301  C CB  . GLN A 1 39  ? 20.48412 8.31657   31.94691  1.000 64.49038  ? 39  GLN H CB  1 
ATOM   302  C CG  . GLN A 1 39  ? 19.97258 9.71566   31.64999  1.000 69.35415  ? 39  GLN H CG  1 
ATOM   303  C CD  . GLN A 1 39  ? 18.53648 9.91666   32.08772  1.000 66.00833  ? 39  GLN H CD  1 
ATOM   304  O OE1 . GLN A 1 39  ? 17.85283 8.96597   32.46613  1.000 71.70208  ? 39  GLN H OE1 1 
ATOM   305  N NE2 . GLN A 1 39  ? 18.07075 11.15991  32.03923  1.000 72.63820  ? 39  GLN H NE2 1 
ATOM   306  N N   . ALA A 1 40  ? 23.57483 9.30725   33.41945  1.000 84.09714  ? 40  ALA H N   1 
ATOM   307  C CA  . ALA A 1 40  ? 24.10460 9.71013   34.71104  1.000 84.24336  ? 40  ALA H CA  1 
ATOM   308  C C   . ALA A 1 40  ? 23.01357 10.43010  35.50654  1.000 75.07314  ? 40  ALA H C   1 
ATOM   309  O O   . ALA A 1 40  ? 22.09808 11.01566  34.91977  1.000 84.19269  ? 40  ALA H O   1 
ATOM   310  C CB  . ALA A 1 40  ? 25.32175 10.61545  34.51907  1.000 89.15756  ? 40  ALA H CB  1 
ATOM   311  N N   . PRO A 1 41  ? 23.07430 10.39755  36.84009  1.000 81.30610  ? 41  PRO H N   1 
ATOM   312  C CA  . PRO A 1 41  ? 21.96037 10.94015  37.63703  1.000 83.18045  ? 41  PRO H CA  1 
ATOM   313  C C   . PRO A 1 41  ? 21.75359 12.42465  37.37677  1.000 82.39157  ? 41  PRO H C   1 
ATOM   314  O O   . PRO A 1 41  ? 22.64272 13.24829  37.60718  1.000 73.67662  ? 41  PRO H O   1 
ATOM   315  C CB  . PRO A 1 41  ? 22.38765 10.66244  39.08676  1.000 65.03263  ? 41  PRO H CB  1 
ATOM   316  C CG  . PRO A 1 41  ? 23.61174 9.78672   38.99694  1.000 82.39812  ? 41  PRO H CG  1 
ATOM   317  C CD  . PRO A 1 41  ? 24.23837 10.09662  37.68806  1.000 86.91585  ? 41  PRO H CD  1 
ATOM   318  N N   . GLY A 1 42  ? 20.56095 12.75808  36.88898  1.000 68.98055  ? 42  GLY H N   1 
ATOM   319  C CA  . GLY A 1 42  ? 20.24634 14.12329  36.51496  1.000 66.23875  ? 42  GLY H CA  1 
ATOM   320  C C   . GLY A 1 42  ? 21.05488 14.65083  35.35292  1.000 79.16020  ? 42  GLY H C   1 
ATOM   321  O O   . GLY A 1 42  ? 21.37881 15.84214  35.32108  1.000 83.52545  ? 42  GLY H O   1 
ATOM   322  N N   . GLN A 1 43  ? 21.38915 13.79371  34.39190  1.000 76.67793  ? 43  GLN H N   1 
ATOM   323  C CA  . GLN A 1 43  ? 22.17264 14.16984  33.22504  1.000 70.98854  ? 43  GLN H CA  1 
ATOM   324  C C   . GLN A 1 43  ? 21.48298 13.64356  31.97203  1.000 62.92892  ? 43  GLN H C   1 
ATOM   325  O O   . GLN A 1 43  ? 20.39815 13.05689  32.03100  1.000 58.38901  ? 43  GLN H O   1 
ATOM   326  C CB  . GLN A 1 43  ? 23.60930 13.64104  33.32775  1.000 78.90523  ? 43  GLN H CB  1 
ATOM   327  C CG  . GLN A 1 43  ? 24.35920 14.11420  34.56372  1.000 77.43823  ? 43  GLN H CG  1 
ATOM   328  C CD  . GLN A 1 43  ? 25.78215 14.53595  34.25633  1.000 92.18019  ? 43  GLN H CD  1 
ATOM   329  O OE1 . GLN A 1 43  ? 26.47767 13.88984  33.47262  1.000 117.60651 ? 43  GLN H OE1 1 
ATOM   330  N NE2 . GLN A 1 43  ? 26.22266 15.62650  34.87309  1.000 87.09480  ? 43  GLN H NE2 1 
ATOM   331  N N   . GLY A 1 44  ? 22.12407 13.85948  30.82574  1.000 61.53364  ? 44  GLY H N   1 
ATOM   332  C CA  . GLY A 1 44  ? 21.56995 13.44590  29.55632  1.000 81.68111  ? 44  GLY H CA  1 
ATOM   333  C C   . GLY A 1 44  ? 21.81028 11.97881  29.25512  1.000 81.52753  ? 44  GLY H C   1 
ATOM   334  O O   . GLY A 1 44  ? 22.41986 11.23559  30.02422  1.000 67.52490  ? 44  GLY H O   1 
ATOM   335  N N   . LEU A 1 45  ? 21.30903 11.56191  28.09523  1.000 73.07178  ? 45  LEU H N   1 
ATOM   336  C CA  . LEU A 1 45  ? 21.45666 10.19165  27.62680  1.000 63.30272  ? 45  LEU H CA  1 
ATOM   337  C C   . LEU A 1 45  ? 22.72313 10.05517  26.79161  1.000 57.46330  ? 45  LEU H C   1 
ATOM   338  O O   . LEU A 1 45  ? 23.02193 10.90772  25.95070  1.000 76.38548  ? 45  LEU H O   1 
ATOM   339  C CB  . LEU A 1 45  ? 20.23800 9.77301   26.80195  1.000 52.82594  ? 45  LEU H CB  1 
ATOM   340  C CG  . LEU A 1 45  ? 18.86612 10.12425  27.38209  1.000 54.03604  ? 45  LEU H CG  1 
ATOM   341  C CD1 . LEU A 1 45  ? 17.81272 10.17926  26.28875  1.000 43.49313  ? 45  LEU H CD1 1 
ATOM   342  C CD2 . LEU A 1 45  ? 18.46849 9.11664   28.44542  1.000 68.24516  ? 45  LEU H CD2 1 
ATOM   343  N N   . GLU A 1 46  ? 23.47074 8.98102   27.03552  1.000 43.88358  ? 46  GLU H N   1 
ATOM   344  C CA  . GLU A 1 46  ? 24.69130 8.68187   26.29602  1.000 58.75991  ? 46  GLU H CA  1 
ATOM   345  C C   . GLU A 1 46  ? 24.52249 7.34339   25.59202  1.000 79.25766  ? 46  GLU H C   1 
ATOM   346  O O   . GLU A 1 46  ? 24.27756 6.32265   26.24377  1.000 69.69001  ? 46  GLU H O   1 
ATOM   347  C CB  . GLU A 1 46  ? 25.90815 8.65255   27.22384  1.000 51.49974  ? 46  GLU H CB  1 
ATOM   348  C CG  . GLU A 1 46  ? 26.02285 9.85727   28.14504  1.000 81.81183  ? 46  GLU H CG  1 
ATOM   349  C CD  . GLU A 1 46  ? 26.47374 9.48116   29.54558  1.000 111.87159 ? 46  GLU H CD  1 
ATOM   350  O OE1 . GLU A 1 46  ? 27.56114 8.88051   29.68057  1.000 101.56361 ? 46  GLU H OE1 1 
ATOM   351  O OE2 . GLU A 1 46  ? 25.74154 9.78656   30.51153  1.000 98.12325  ? 46  GLU H OE2 1 
ATOM   352  N N   . TRP A 1 47  ? 24.65444 7.34995   24.26819  1.000 76.54979  ? 47  TRP H N   1 
ATOM   353  C CA  . TRP A 1 47  ? 24.53174 6.12157   23.49611  1.000 68.38555  ? 47  TRP H CA  1 
ATOM   354  C C   . TRP A 1 47  ? 25.76253 5.24546   23.68865  1.000 74.65956  ? 47  TRP H C   1 
ATOM   355  O O   . TRP A 1 47  ? 26.89835 5.72743   23.66530  1.000 72.61759  ? 47  TRP H O   1 
ATOM   356  C CB  . TRP A 1 47  ? 24.35178 6.44406   22.01640  1.000 74.77109  ? 47  TRP H CB  1 
ATOM   357  C CG  . TRP A 1 47  ? 24.19605 5.23957   21.13942  1.000 78.03579  ? 47  TRP H CG  1 
ATOM   358  C CD1 . TRP A 1 47  ? 23.13179 4.38706   21.09781  1.000 83.67861  ? 47  TRP H CD1 1 
ATOM   359  C CD2 . TRP A 1 47  ? 25.14277 4.74602   20.18407  1.000 80.02386  ? 47  TRP H CD2 1 
ATOM   360  N NE1 . TRP A 1 47  ? 23.35269 3.39860   20.16861  1.000 84.77908  ? 47  TRP H NE1 1 
ATOM   361  C CE2 . TRP A 1 47  ? 24.58142 3.59538   19.59566  1.000 74.71145  ? 47  TRP H CE2 1 
ATOM   362  C CE3 . TRP A 1 47  ? 26.40945 5.16667   19.76794  1.000 70.47129  ? 47  TRP H CE3 1 
ATOM   363  C CZ2 . TRP A 1 47  ? 25.24205 2.86186   18.61378  1.000 62.26132  ? 47  TRP H CZ2 1 
ATOM   364  C CZ3 . TRP A 1 47  ? 27.06430 4.43555   18.79623  1.000 69.49752  ? 47  TRP H CZ3 1 
ATOM   365  C CH2 . TRP A 1 47  ? 26.47977 3.29672   18.22883  1.000 80.80064  ? 47  TRP H CH2 1 
ATOM   366  N N   . MET A 1 48  ? 25.53230 3.94667   23.86878  1.000 73.18284  ? 48  MET H N   1 
ATOM   367  C CA  . MET A 1 48  ? 26.60392 2.98586   24.09558  1.000 76.80497  ? 48  MET H CA  1 
ATOM   368  C C   . MET A 1 48  ? 26.85119 2.07967   22.89965  1.000 67.43723  ? 48  MET H C   1 
ATOM   369  O O   . MET A 1 48  ? 28.00226 1.89126   22.49464  1.000 80.50150  ? 48  MET H O   1 
ATOM   370  C CB  . MET A 1 48  ? 26.29178 2.13725   25.33637  1.000 83.59690  ? 48  MET H CB  1 
ATOM   371  C CG  . MET A 1 48  ? 26.04045 2.95171   26.59356  1.000 60.23360  ? 48  MET H CG  1 
ATOM   372  S SD  . MET A 1 48  ? 25.81365 1.91485   28.04923  1.000 74.35510  ? 48  MET H SD  1 
ATOM   373  C CE  . MET A 1 48  ? 27.43353 1.16290   28.18510  1.000 66.41546  ? 48  MET H CE  1 
ATOM   374  N N   . GLY A 1 49  ? 25.80130 1.51024   22.32357  1.000 74.50452  ? 49  GLY H N   1 
ATOM   375  C CA  . GLY A 1 49  ? 25.96323 0.63802   21.17887  1.000 85.38847  ? 49  GLY H CA  1 
ATOM   376  C C   . GLY A 1 49  ? 24.65961 -0.05001  20.84132  1.000 80.97011  ? 49  GLY H C   1 
ATOM   377  O O   . GLY A 1 49  ? 23.61791 0.19293   21.45918  1.000 77.09997  ? 49  GLY H O   1 
ATOM   378  N N   . TRP A 1 50  ? 24.73787 -0.91951  19.83598  1.000 68.96346  ? 50  TRP H N   1 
ATOM   379  C CA  . TRP A 1 50  ? 23.59249 -1.71381  19.42097  1.000 74.17246  ? 50  TRP H CA  1 
ATOM   380  C C   . TRP A 1 50  ? 24.04684 -3.12467  19.07864  1.000 82.68931  ? 50  TRP H C   1 
ATOM   381  O O   . TRP A 1 50  ? 25.19677 -3.34938  18.69187  1.000 81.23180  ? 50  TRP H O   1 
ATOM   382  C CB  . TRP A 1 50  ? 22.85869 -1.08059  18.22533  1.000 94.38657  ? 50  TRP H CB  1 
ATOM   383  C CG  . TRP A 1 50  ? 23.70825 -0.85900  17.00221  1.000 95.55087  ? 50  TRP H CG  1 
ATOM   384  C CD1 . TRP A 1 50  ? 24.26330 0.31979   16.59584  1.000 93.08662  ? 50  TRP H CD1 1 
ATOM   385  C CD2 . TRP A 1 50  ? 24.06474 -1.83150  16.00917  1.000 78.20016  ? 50  TRP H CD2 1 
ATOM   386  N NE1 . TRP A 1 50  ? 24.95935 0.13848   15.42580  1.000 76.80044  ? 50  TRP H NE1 1 
ATOM   387  C CE2 . TRP A 1 50  ? 24.85152 -1.17257  15.04373  1.000 78.89055  ? 50  TRP H CE2 1 
ATOM   388  C CE3 . TRP A 1 50  ? 23.80266 -3.19568  15.84756  1.000 87.26013  ? 50  TRP H CE3 1 
ATOM   389  C CZ2 . TRP A 1 50  ? 25.37788 -1.83060  13.93423  1.000 97.50010  ? 50  TRP H CZ2 1 
ATOM   390  C CZ3 . TRP A 1 50  ? 24.32722 -3.84700  14.74600  1.000 94.60918  ? 50  TRP H CZ3 1 
ATOM   391  C CH2 . TRP A 1 50  ? 25.10530 -3.16432  13.80391  1.000 97.82019  ? 50  TRP H CH2 1 
ATOM   392  N N   . ILE A 1 51  ? 23.12882 -4.07459  19.23811  1.000 81.12639  ? 51  ILE H N   1 
ATOM   393  C CA  . ILE A 1 51  ? 23.35626 -5.47049  18.88349  1.000 85.08956  ? 51  ILE H CA  1 
ATOM   394  C C   . ILE A 1 51  ? 22.09205 -6.00761  18.22544  1.000 86.22046  ? 51  ILE H C   1 
ATOM   395  O O   . ILE A 1 51  ? 20.97823 -5.75340  18.69673  1.000 77.71405  ? 51  ILE H O   1 
ATOM   396  C CB  . ILE A 1 51  ? 23.75178 -6.31546  20.11576  1.000 62.01890  ? 51  ILE H CB  1 
ATOM   397  C CG1 . ILE A 1 51  ? 23.87689 -7.79498  19.74252  1.000 72.91455  ? 51  ILE H CG1 1 
ATOM   398  C CG2 . ILE A 1 51  ? 22.76005 -6.11677  21.25572  1.000 82.21418  ? 51  ILE H CG2 1 
ATOM   399  C CD1 . ILE A 1 51  ? 24.79213 -8.58069  20.65323  1.000 58.93241  ? 51  ILE H CD1 1 
ATOM   400  N N   . HIS A 1 52  ? 22.26188 -6.73708  17.12066  1.000 83.61617  ? 52  HIS H N   1 
ATOM   401  C CA  . HIS A 1 52  ? 21.12870 -7.33340  16.42818  1.000 84.84062  ? 52  HIS H CA  1 
ATOM   402  C C   . HIS A 1 52  ? 21.05319 -8.81565  16.74924  1.000 79.51495  ? 52  HIS H C   1 
ATOM   403  O O   . HIS A 1 52  ? 22.02058 -9.54688  16.48457  1.000 77.80112  ? 52  HIS H O   1 
ATOM   404  C CB  . HIS A 1 52  ? 21.23385 -7.12571  14.92254  1.000 80.01796  ? 52  HIS H CB  1 
ATOM   405  C CG  . HIS A 1 52  ? 19.91455 -7.19443  14.21870  1.000 78.32976  ? 52  HIS H CG  1 
ATOM   406  N ND1 . HIS A 1 52  ? 19.22243 -8.37450  14.05212  1.000 82.48026  ? 52  HIS H ND1 1 
ATOM   407  C CD2 . HIS A 1 52  ? 19.15049 -6.22810  13.65694  1.000 71.92857  ? 52  HIS H CD2 1 
ATOM   408  C CE1 . HIS A 1 52  ? 18.09339 -8.13366  13.41014  1.000 74.28810  ? 52  HIS H CE1 1 
ATOM   409  N NE2 . HIS A 1 52  ? 18.02505 -6.83873  13.15941  1.000 77.49759  ? 52  HIS H NE2 1 
ATOM   410  N N   . PRO A 1 53  ? 19.94795 -9.29541  17.32677  1.000 76.45048  ? 53  PRO H N   1 
ATOM   411  C CA  . PRO A 1 53  ? 19.85489 -10.72796 17.65787  1.000 82.67583  ? 53  PRO H CA  1 
ATOM   412  C C   . PRO A 1 53  ? 20.01646 -11.65264 16.46280  1.000 84.86331  ? 53  PRO H C   1 
ATOM   413  O O   . PRO A 1 53  ? 20.59949 -12.73539 16.60130  1.000 91.80455  ? 53  PRO H O   1 
ATOM   414  C CB  . PRO A 1 53  ? 18.45362 -10.83869 18.27179  1.000 86.78917  ? 53  PRO H CB  1 
ATOM   415  C CG  . PRO A 1 53  ? 18.21439 -9.49202  18.86717  1.000 80.18107  ? 53  PRO H CG  1 
ATOM   416  C CD  . PRO A 1 53  ? 18.82563 -8.52590  17.88977  1.000 59.63082  ? 53  PRO H CD  1 
ATOM   417  N N   . ASN A 1 54  ? 19.50735 -11.26159 15.29172  1.000 79.95988  ? 54  ASN H N   1 
ATOM   418  C CA  . ASN A 1 54  ? 19.55529 -12.14600 14.13044  1.000 86.81222  ? 54  ASN H CA  1 
ATOM   419  C C   . ASN A 1 54  ? 20.98684 -12.40899 13.67773  1.000 86.40269  ? 54  ASN H C   1 
ATOM   420  O O   . ASN A 1 54  ? 21.33910 -13.54781 13.34903  1.000 88.87944  ? 54  ASN H O   1 
ATOM   421  C CB  . ASN A 1 54  ? 18.73562 -11.55438 12.98469  1.000 92.10146  ? 54  ASN H CB  1 
ATOM   422  C CG  . ASN A 1 54  ? 17.81118 -12.57097 12.34652  1.000 94.55918  ? 54  ASN H CG  1 
ATOM   423  O OD1 . ASN A 1 54  ? 18.02429 -13.77759 12.46260  1.000 90.87507  ? 54  ASN H OD1 1 
ATOM   424  N ND2 . ASN A 1 54  ? 16.77777 -12.08813 11.66598  1.000 101.37824 ? 54  ASN H ND2 1 
ATOM   425  N N   . SER A 1 55  ? 21.82470 -11.37423 13.64957  1.000 80.16039  ? 55  SER H N   1 
ATOM   426  C CA  . SER A 1 55  ? 23.18309 -11.49694 13.13816  1.000 82.59196  ? 55  SER H CA  1 
ATOM   427  C C   . SER A 1 55  ? 24.25093 -11.51033 14.21845  1.000 89.51032  ? 55  SER H C   1 
ATOM   428  O O   . SER A 1 55  ? 25.31996 -12.08430 14.00136  1.000 87.98837  ? 55  SER H O   1 
ATOM   429  C CB  . SER A 1 55  ? 23.48807 -10.35352 12.16211  1.000 96.36809  ? 55  SER H CB  1 
ATOM   430  O OG  . SER A 1 55  ? 23.34354 -9.09352  12.79409  1.000 96.83477  ? 55  SER H OG  1 
ATOM   431  N N   . GLY A 1 56  ? 23.99280 -10.89909 15.37110  1.000 95.89061  ? 56  GLY H N   1 
ATOM   432  C CA  . GLY A 1 56  ? 25.00705 -10.78286 16.39614  1.000 82.60410  ? 56  GLY H CA  1 
ATOM   433  C C   . GLY A 1 56  ? 25.99267 -9.65736  16.18844  1.000 87.27646  ? 56  GLY H C   1 
ATOM   434  O O   . GLY A 1 56  ? 26.95622 -9.55062  16.95563  1.000 79.42155  ? 56  GLY H O   1 
ATOM   435  N N   . ALA A 1 57  ? 25.78784 -8.81948  15.17473  1.000 95.20922  ? 57  ALA H N   1 
ATOM   436  C CA  . ALA A 1 57  ? 26.69670 -7.71236  14.91571  1.000 93.45693  ? 57  ALA H CA  1 
ATOM   437  C C   . ALA A 1 57  ? 26.63053 -6.68914  16.04186  1.000 92.57184  ? 57  ALA H C   1 
ATOM   438  O O   . ALA A 1 57  ? 25.56548 -6.43255  16.61038  1.000 81.57791  ? 57  ALA H O   1 
ATOM   439  C CB  . ALA A 1 57  ? 26.35951 -7.04853  13.58145  1.000 79.08773  ? 57  ALA H CB  1 
ATOM   440  N N   . THR A 1 58  ? 27.78223 -6.10538  16.36511  1.000 85.63904  ? 58  THR H N   1 
ATOM   441  C CA  . THR A 1 58  ? 27.89238 -5.12580  17.43669  1.000 85.18516  ? 58  THR H CA  1 
ATOM   442  C C   . THR A 1 58  ? 28.67534 -3.91987  16.94316  1.000 96.00284  ? 58  THR H C   1 
ATOM   443  O O   . THR A 1 58  ? 29.73896 -4.07232  16.33390  1.000 101.34473 ? 58  THR H O   1 
ATOM   444  C CB  . THR A 1 58  ? 28.57952 -5.72246  18.67054  1.000 91.93452  ? 58  THR H CB  1 
ATOM   445  O OG1 . THR A 1 58  ? 29.77291 -6.40854  18.27123  1.000 93.24651  ? 58  THR H OG1 1 
ATOM   446  C CG2 . THR A 1 58  ? 27.65259 -6.69640  19.38048  1.000 97.76998  ? 58  THR H CG2 1 
ATOM   447  N N   . LYS A 1 59  ? 28.14662 -2.72675  17.20571  1.000 92.46808  ? 59  LYS H N   1 
ATOM   448  C CA  . LYS A 1 59  ? 28.84379 -1.47344  16.93431  1.000 88.68262  ? 59  LYS H CA  1 
ATOM   449  C C   . LYS A 1 59  ? 28.72190 -0.59280  18.16963  1.000 95.50923  ? 59  LYS H C   1 
ATOM   450  O O   . LYS A 1 59  ? 27.62837 -0.11642  18.49114  1.000 88.20710  ? 59  LYS H O   1 
ATOM   451  C CB  . LYS A 1 59  ? 28.27600 -0.77073  15.70133  1.000 85.68620  ? 59  LYS H CB  1 
ATOM   452  C CG  . LYS A 1 59  ? 29.00975 0.50952   15.33262  1.000 99.33787  ? 59  LYS H CG  1 
ATOM   453  C CD  . LYS A 1 59  ? 30.42131 0.21558   14.84888  1.000 119.87284 ? 59  LYS H CD  1 
ATOM   454  C CE  . LYS A 1 59  ? 31.16139 1.49252   14.48145  1.000 119.46300 ? 59  LYS H CE  1 
ATOM   455  N NZ  . LYS A 1 59  ? 30.54566 2.18111   13.31312  1.000 113.08060 ? 59  LYS H NZ  1 
ATOM   456  N N   . TYR A 1 60  ? 29.83695 -0.38137  18.85881  1.000 93.59712  ? 60  TYR H N   1 
ATOM   457  C CA  . TYR A 1 60  ? 29.87285 0.41497   20.07474  1.000 72.95448  ? 60  TYR H CA  1 
ATOM   458  C C   . TYR A 1 60  ? 30.30207 1.84432   19.76570  1.000 74.77029  ? 60  TYR H C   1 
ATOM   459  O O   . TYR A 1 60  ? 30.88204 2.13433   18.71643  1.000 88.39923  ? 60  TYR H O   1 
ATOM   460  C CB  . TYR A 1 60  ? 30.82887 -0.20191  21.10015  1.000 78.73015  ? 60  TYR H CB  1 
ATOM   461  C CG  . TYR A 1 60  ? 30.66619 -1.69377  21.28674  1.000 92.03945  ? 60  TYR H CG  1 
ATOM   462  C CD1 . TYR A 1 60  ? 29.46064 -2.23455  21.71409  1.000 99.41412  ? 60  TYR H CD1 1 
ATOM   463  C CD2 . TYR A 1 60  ? 31.72107 -2.56182  21.03536  1.000 87.66100  ? 60  TYR H CD2 1 
ATOM   464  C CE1 . TYR A 1 60  ? 29.31094 -3.59865  21.88636  1.000 93.97404  ? 60  TYR H CE1 1 
ATOM   465  C CE2 . TYR A 1 60  ? 31.58088 -3.92588  21.20360  1.000 76.32595  ? 60  TYR H CE2 1 
ATOM   466  C CZ  . TYR A 1 60  ? 30.37430 -4.43898  21.62915  1.000 87.52517  ? 60  TYR H CZ  1 
ATOM   467  O OH  . TYR A 1 60  ? 30.23020 -5.79674  21.79850  1.000 97.65529  ? 60  TYR H OH  1 
ATOM   468  N N   . ALA A 1 61  ? 30.00420 2.74059   20.70088  1.000 78.40508  ? 61  ALA H N   1 
ATOM   469  C CA  . ALA A 1 61  ? 30.46866 4.11289   20.60066  1.000 64.93208  ? 61  ALA H CA  1 
ATOM   470  C C   . ALA A 1 61  ? 31.94945 4.19592   20.95995  1.000 74.76939  ? 61  ALA H C   1 
ATOM   471  O O   . ALA A 1 61  ? 32.51538 3.29793   21.58968  1.000 96.19784  ? 61  ALA H O   1 
ATOM   472  C CB  . ALA A 1 61  ? 29.65090 5.02954   21.51061  1.000 72.85107  ? 61  ALA H CB  1 
ATOM   473  N N   . GLN A 1 62  ? 32.57951 5.29588   20.54135  1.000 76.02443  ? 62  GLN H N   1 
ATOM   474  C CA  . GLN A 1 62  ? 34.00660 5.47157   20.79413  1.000 86.60466  ? 62  GLN H CA  1 
ATOM   475  C C   . GLN A 1 62  ? 34.29919 5.55420   22.28744  1.000 91.44432  ? 62  GLN H C   1 
ATOM   476  O O   . GLN A 1 62  ? 35.30166 5.00714   22.76262  1.000 95.17183  ? 62  GLN H O   1 
ATOM   477  C CB  . GLN A 1 62  ? 34.51616 6.72098   20.07491  1.000 106.51787 ? 62  GLN H CB  1 
ATOM   478  C CG  . GLN A 1 62  ? 35.95699 7.08592   20.40063  1.000 123.08518 ? 62  GLN H CG  1 
ATOM   479  C CD  . GLN A 1 62  ? 36.94519 6.50232   19.40942  1.000 129.87619 ? 62  GLN H CD  1 
ATOM   480  O OE1 . GLN A 1 62  ? 36.80356 5.35985   18.97300  1.000 142.95552 ? 62  GLN H OE1 1 
ATOM   481  N NE2 . GLN A 1 62  ? 37.95402 7.28688   19.04805  1.000 110.59532 ? 62  GLN H NE2 1 
ATOM   482  N N   . LYS A 1 63  ? 33.43312 6.23341   23.04398  1.000 95.09810  ? 63  LYS H N   1 
ATOM   483  C CA  . LYS A 1 63  ? 33.65997 6.38475   24.47840  1.000 90.47892  ? 63  LYS H CA  1 
ATOM   484  C C   . LYS A 1 63  ? 33.62207 5.03901   25.19355  1.000 86.95255  ? 63  LYS H C   1 
ATOM   485  O O   . LYS A 1 63  ? 34.37273 4.81489   26.15062  1.000 93.27050  ? 63  LYS H O   1 
ATOM   486  C CB  . LYS A 1 63  ? 32.62407 7.33767   25.07613  1.000 91.30504  ? 63  LYS H CB  1 
ATOM   487  C CG  . LYS A 1 63  ? 32.90642 7.74190   26.51475  1.000 101.33087 ? 63  LYS H CG  1 
ATOM   488  C CD  . LYS A 1 63  ? 32.19175 9.03483   26.87833  1.000 100.39961 ? 63  LYS H CD  1 
ATOM   489  C CE  . LYS A 1 63  ? 32.97207 10.25197  26.40645  1.000 105.31849 ? 63  LYS H CE  1 
ATOM   490  N NZ  . LYS A 1 63  ? 34.43316 9.97966   26.31172  1.000 98.98953  ? 63  LYS H NZ  1 
ATOM   491  N N   . PHE A 1 64  ? 32.75701 4.13085   24.74513  1.000 90.83783  ? 64  PHE H N   1 
ATOM   492  C CA  . PHE A 1 64  ? 32.56961 2.84171   25.39689  1.000 77.42279  ? 64  PHE H CA  1 
ATOM   493  C C   . PHE A 1 64  ? 33.30559 1.70162   24.70575  1.000 81.93481  ? 64  PHE H C   1 
ATOM   494  O O   . PHE A 1 64  ? 33.23886 0.56609   25.18435  1.000 92.02117  ? 64  PHE H O   1 
ATOM   495  C CB  . PHE A 1 64  ? 31.07602 2.50785   25.47903  1.000 67.56793  ? 64  PHE H CB  1 
ATOM   496  C CG  . PHE A 1 64  ? 30.26956 3.52414   26.23556  1.000 82.33604  ? 64  PHE H CG  1 
ATOM   497  C CD1 . PHE A 1 64  ? 30.22705 3.50297   27.61931  1.000 89.71103  ? 64  PHE H CD1 1 
ATOM   498  C CD2 . PHE A 1 64  ? 29.55417 4.50100   25.56331  1.000 82.99626  ? 64  PHE H CD2 1 
ATOM   499  C CE1 . PHE A 1 64  ? 29.48772 4.43762   28.31899  1.000 81.57351  ? 64  PHE H CE1 1 
ATOM   500  C CE2 . PHE A 1 64  ? 28.81212 5.43794   26.25666  1.000 76.44129  ? 64  PHE H CE2 1 
ATOM   501  C CZ  . PHE A 1 64  ? 28.77889 5.40626   27.63608  1.000 89.39691  ? 64  PHE H CZ  1 
ATOM   502  N N   . GLU A 1 65  ? 34.01030 1.97192   23.60868  1.000 76.49816  ? 65  GLU H N   1 
ATOM   503  C CA  . GLU A 1 65  ? 34.64662 0.90399   22.84738  1.000 83.57187  ? 65  GLU H CA  1 
ATOM   504  C C   . GLU A 1 65  ? 35.67935 0.16504   23.69107  1.000 80.46413  ? 65  GLU H C   1 
ATOM   505  O O   . GLU A 1 65  ? 36.44582 0.77298   24.44337  1.000 76.31994  ? 65  GLU H O   1 
ATOM   506  C CB  . GLU A 1 65  ? 35.30707 1.47150   21.59003  1.000 85.75416  ? 65  GLU H CB  1 
ATOM   507  C CG  . GLU A 1 65  ? 35.37080 0.49340   20.42715  1.000 83.58616  ? 65  GLU H CG  1 
ATOM   508  C CD  . GLU A 1 65  ? 34.22124 0.66536   19.45254  1.000 117.58932 ? 65  GLU H CD  1 
ATOM   509  O OE1 . GLU A 1 65  ? 34.05982 1.77909   18.91030  1.000 110.70598 ? 65  GLU H OE1 1 
ATOM   510  O OE2 . GLU A 1 65  ? 33.48049 -0.31489  19.22561  1.000 132.42800 ? 65  GLU H OE2 1 
ATOM   511  N N   . GLY A 1 66  ? 35.69583 -1.15932  23.55591  1.000 63.67980  ? 66  GLY H N   1 
ATOM   512  C CA  . GLY A 1 66  ? 36.65775 -1.98731  24.25567  1.000 66.87700  ? 66  GLY H CA  1 
ATOM   513  C C   . GLY A 1 66  ? 36.17301 -2.55742  25.57327  1.000 85.94724  ? 66  GLY H C   1 
ATOM   514  O O   . GLY A 1 66  ? 36.06534 -3.77879  25.71999  1.000 83.15276  ? 66  GLY H O   1 
ATOM   515  N N   . TRP A 1 67  ? 35.87639 -1.68987  26.54199  1.000 79.74832  ? 67  TRP H N   1 
ATOM   516  C CA  . TRP A 1 67  ? 35.52342 -2.15014  27.87940  1.000 85.47408  ? 67  TRP H CA  1 
ATOM   517  C C   . TRP A 1 67  ? 34.05802 -2.54393  28.02086  1.000 89.12337  ? 67  TRP H C   1 
ATOM   518  O O   . TRP A 1 67  ? 33.68372 -3.08808  29.06532  1.000 105.39718 ? 67  TRP H O   1 
ATOM   519  C CB  . TRP A 1 67  ? 35.87309 -1.08341  28.92358  1.000 88.09785  ? 67  TRP H CB  1 
ATOM   520  C CG  . TRP A 1 67  ? 35.40132 0.30242   28.59782  1.000 70.86736  ? 67  TRP H CG  1 
ATOM   521  C CD1 . TRP A 1 67  ? 35.86244 1.11590   27.60357  1.000 66.04522  ? 67  TRP H CD1 1 
ATOM   522  C CD2 . TRP A 1 67  ? 34.38236 1.04287   29.28044  1.000 75.71878  ? 67  TRP H CD2 1 
ATOM   523  N NE1 . TRP A 1 67  ? 35.19117 2.31373   27.62194  1.000 77.32417  ? 67  TRP H NE1 1 
ATOM   524  C CE2 . TRP A 1 67  ? 34.27737 2.29473   28.64230  1.000 75.05131  ? 67  TRP H CE2 1 
ATOM   525  C CE3 . TRP A 1 67  ? 33.54804 0.76848   30.36843  1.000 82.25494  ? 67  TRP H CE3 1 
ATOM   526  C CZ2 . TRP A 1 67  ? 33.37187 3.26960   29.05509  1.000 71.46378  ? 67  TRP H CZ2 1 
ATOM   527  C CZ3 . TRP A 1 67  ? 32.65072 1.73875   30.77731  1.000 90.77828  ? 67  TRP H CZ3 1 
ATOM   528  C CH2 . TRP A 1 67  ? 32.56884 2.97277   30.12134  1.000 82.00005  ? 67  TRP H CH2 1 
ATOM   529  N N   . VAL A 1 68  ? 33.22413 -2.29040  27.01644  1.000 77.41595  ? 68  VAL H N   1 
ATOM   530  C CA  . VAL A 1 68  ? 31.84490 -2.76115  27.02145  1.000 81.04630  ? 68  VAL H CA  1 
ATOM   531  C C   . VAL A 1 68  ? 31.72972 -3.89384  26.01086  1.000 80.54768  ? 68  VAL H C   1 
ATOM   532  O O   . VAL A 1 68  ? 32.45643 -3.94138  25.01114  1.000 79.95836  ? 68  VAL H O   1 
ATOM   533  C CB  . VAL A 1 68  ? 30.83054 -1.63593  26.71455  1.000 78.05032  ? 68  VAL H CB  1 
ATOM   534  C CG1 . VAL A 1 68  ? 30.78662 -1.32878  25.22467  1.000 109.62889 ? 68  VAL H CG1 1 
ATOM   535  C CG2 . VAL A 1 68  ? 29.44746 -2.00327  27.23440  1.000 77.89512  ? 68  VAL H CG2 1 
ATOM   536  N N   . THR A 1 69  ? 30.82434 -4.82795  26.29006  1.000 70.95036  ? 69  THR H N   1 
ATOM   537  C CA  . THR A 1 69  ? 30.61748 -5.98037  25.42441  1.000 79.62974  ? 69  THR H CA  1 
ATOM   538  C C   . THR A 1 69  ? 29.14177 -6.34226  25.42322  1.000 89.88316  ? 69  THR H C   1 
ATOM   539  O O   . THR A 1 69  ? 28.54153 -6.51434  26.48831  1.000 83.67147  ? 69  THR H O   1 
ATOM   540  C CB  . THR A 1 69  ? 31.45862 -7.17923  25.88145  1.000 81.33934  ? 69  THR H CB  1 
ATOM   541  O OG1 . THR A 1 69  ? 32.82917 -6.96804  25.52000  1.000 76.11204  ? 69  THR H OG1 1 
ATOM   542  C CG2 . THR A 1 69  ? 30.96271 -8.46246  25.22959  1.000 66.29414  ? 69  THR H CG2 1 
ATOM   543  N N   . MET A 1 70  ? 28.56370 -6.45264  24.23108  1.000 74.69402  ? 70  MET H N   1 
ATOM   544  C CA  . MET A 1 70  ? 27.16457 -6.81551  24.06105  1.000 69.76042  ? 70  MET H CA  1 
ATOM   545  C C   . MET A 1 70  ? 27.07473 -8.23602  23.52204  1.000 77.15470  ? 70  MET H C   1 
ATOM   546  O O   . MET A 1 70  ? 27.69346 -8.55770  22.50218  1.000 99.01576  ? 70  MET H O   1 
ATOM   547  C CB  . MET A 1 70  ? 26.45748 -5.84269  23.11480  1.000 74.32292  ? 70  MET H CB  1 
ATOM   548  C CG  . MET A 1 70  ? 25.77449 -4.67751  23.81265  1.000 74.64603  ? 70  MET H CG  1 
ATOM   549  S SD  . MET A 1 70  ? 25.77910 -3.17629  22.81284  1.000 73.24044  ? 70  MET H SD  1 
ATOM   550  C CE  . MET A 1 70  ? 26.34184 -1.96977  24.01030  1.000 91.32457  ? 70  MET H CE  1 
ATOM   551  N N   . THR A 1 71  ? 26.31263 -9.08024  24.20997  1.000 70.80476  ? 71  THR H N   1 
ATOM   552  C CA  . THR A 1 71  ? 26.06585 -10.45236 23.79413  1.000 68.38737  ? 71  THR H CA  1 
ATOM   553  C C   . THR A 1 71  ? 24.56477 -10.67616 23.65571  1.000 76.92962  ? 71  THR H C   1 
ATOM   554  O O   . THR A 1 71  ? 23.74839 -9.83228  24.03496  1.000 76.48425  ? 71  THR H O   1 
ATOM   555  C CB  . THR A 1 71  ? 26.66907 -11.45719 24.78711  1.000 97.20884  ? 71  THR H CB  1 
ATOM   556  O OG1 . THR A 1 71  ? 25.82641 -11.56167 25.94101  1.000 94.34267  ? 71  THR H OG1 1 
ATOM   557  C CG2 . THR A 1 71  ? 28.06229 -11.01854 25.21977  1.000 83.52964  ? 71  THR H CG2 1 
ATOM   558  N N   . ARG A 1 72  ? 24.20231 -11.83197 23.10338  1.000 76.64775  ? 72  ARG H N   1 
ATOM   559  C CA  . ARG A 1 72  ? 22.80324 -12.13727 22.84545  1.000 77.17075  ? 72  ARG H CA  1 
ATOM   560  C C   . ARG A 1 72  ? 22.56521 -13.62807 23.03402  1.000 86.35526  ? 72  ARG H C   1 
ATOM   561  O O   . ARG A 1 72  ? 23.49263 -14.43968 22.97573  1.000 98.18263  ? 72  ARG H O   1 
ATOM   562  C CB  . ARG A 1 72  ? 22.38667 -11.69858 21.43578  1.000 89.85796  ? 72  ARG H CB  1 
ATOM   563  C CG  . ARG A 1 72  ? 22.49358 -12.79127 20.38346  1.000 90.48896  ? 72  ARG H CG  1 
ATOM   564  C CD  . ARG A 1 72  ? 22.85390 -12.21124 19.02521  1.000 99.18946  ? 72  ARG H CD  1 
ATOM   565  N NE  . ARG A 1 72  ? 22.92412 -13.22984 17.98346  1.000 109.78505 ? 72  ARG H NE  1 
ATOM   566  C CZ  . ARG A 1 72  ? 23.88676 -14.13630 17.87801  1.000 108.05272 ? 72  ARG H CZ  1 
ATOM   567  N NH1 . ARG A 1 72  ? 24.89658 -14.17707 18.73237  1.000 99.06687  ? 72  ARG H NH1 1 
ATOM   568  N NH2 . ARG A 1 72  ? 23.83816 -15.02116 16.88621  1.000 98.39483  ? 72  ARG H NH2 1 
ATOM   569  N N   . ASP A 1 73  ? 21.29854 -13.97688 23.26787  1.000 89.06128  ? 73  ASP H N   1 
ATOM   570  C CA  . ASP A 1 73  ? 20.89371 -15.37276 23.43059  1.000 98.49721  ? 73  ASP H CA  1 
ATOM   571  C C   . ASP A 1 73  ? 19.49547 -15.51264 22.83331  1.000 104.68608 ? 73  ASP H C   1 
ATOM   572  O O   . ASP A 1 73  ? 18.51292 -15.07644 23.44044  1.000 103.04303 ? 73  ASP H O   1 
ATOM   573  C CB  . ASP A 1 73  ? 20.92222 -15.78850 24.89478  1.000 106.62278 ? 73  ASP H CB  1 
ATOM   574  C CG  . ASP A 1 73  ? 21.42363 -17.20660 25.08862  1.000 116.60196 ? 73  ASP H CG  1 
ATOM   575  O OD1 . ASP A 1 73  ? 21.07010 -18.08215 24.26962  1.000 120.74900 ? 73  ASP H OD1 1 
ATOM   576  O OD2 . ASP A 1 73  ? 22.16903 -17.44648 26.06198  1.000 114.18231 ? 73  ASP H OD2 1 
ATOM   577  N N   . THR A 1 74  ? 19.41728 -16.11780 21.64593  1.000 94.33636  ? 74  THR H N   1 
ATOM   578  C CA  . THR A 1 74  ? 18.13217 -16.27928 20.97595  1.000 99.61760  ? 74  THR H CA  1 
ATOM   579  C C   . THR A 1 74  ? 17.23499 -17.29345 21.67263  1.000 102.63010 ? 74  THR H C   1 
ATOM   580  O O   . THR A 1 74  ? 16.01035 -17.21929 21.52529  1.000 97.50122  ? 74  THR H O   1 
ATOM   581  C CB  . THR A 1 74  ? 18.34281 -16.69548 19.51900  1.000 98.92250  ? 74  THR H CB  1 
ATOM   582  O OG1 . THR A 1 74  ? 18.91071 -18.01037 19.47266  1.000 111.51036 ? 74  THR H OG1 1 
ATOM   583  C CG2 . THR A 1 74  ? 19.27532 -15.71978 18.81615  1.000 94.78100  ? 74  THR H CG2 1 
ATOM   584  N N   . SER A 1 75  ? 17.81394 -18.23878 22.41806  1.000 108.00101 ? 75  SER H N   1 
ATOM   585  C CA  . SER A 1 75  ? 17.00683 -19.25281 23.09030  1.000 114.74611 ? 75  SER H CA  1 
ATOM   586  C C   . SER A 1 75  ? 16.08392 -18.62963 24.13042  1.000 112.15188 ? 75  SER H C   1 
ATOM   587  O O   . SER A 1 75  ? 14.91636 -19.01997 24.24953  1.000 114.83418 ? 75  SER H O   1 
ATOM   588  C CB  . SER A 1 75  ? 17.91396 -20.30004 23.73660  1.000 100.69943 ? 75  SER H CB  1 
ATOM   589  O OG  . SER A 1 75  ? 18.82569 -19.69768 24.63884  1.000 101.24844 ? 75  SER H OG  1 
ATOM   590  N N   . ILE A 1 76  ? 16.58728 -17.65931 24.89179  1.000 107.73411 ? 76  ILE H N   1 
ATOM   591  C CA  . ILE A 1 76  ? 15.81401 -17.00123 25.93774  1.000 104.66424 ? 76  ILE H CA  1 
ATOM   592  C C   . ILE A 1 76  ? 15.40354 -15.59063 25.55816  1.000 103.45029 ? 76  ILE H C   1 
ATOM   593  O O   . ILE A 1 76  ? 14.79327 -14.89499 26.38326  1.000 116.49598 ? 76  ILE H O   1 
ATOM   594  C CB  . ILE A 1 76  ? 16.57745 -16.99181 27.27536  1.000 94.98022  ? 76  ILE H CB  1 
ATOM   595  C CG1 . ILE A 1 76  ? 18.02160 -16.53508 27.06100  1.000 101.33205 ? 76  ILE H CG1 1 
ATOM   596  C CG2 . ILE A 1 76  ? 16.53712 -18.36849 27.91976  1.000 106.10895 ? 76  ILE H CG2 1 
ATOM   597  C CD1 . ILE A 1 76  ? 18.87806 -16.61657 28.30296  1.000 96.59954  ? 76  ILE H CD1 1 
ATOM   598  N N   . SER A 1 77  ? 15.71248 -15.14489 24.33770  1.000 92.51795  ? 77  SER H N   1 
ATOM   599  C CA  . SER A 1 77  ? 15.35840 -13.80355 23.86585  1.000 94.15349  ? 77  SER H CA  1 
ATOM   600  C C   . SER A 1 77  ? 15.91642 -12.72093 24.78809  1.000 85.13380  ? 77  SER H C   1 
ATOM   601  O O   . SER A 1 77  ? 15.23849 -11.74286 25.10991  1.000 85.12463  ? 77  SER H O   1 
ATOM   602  C CB  . SER A 1 77  ? 13.84254 -13.65378 23.70836  1.000 87.53142  ? 77  SER H CB  1 
ATOM   603  O OG  . SER A 1 77  ? 13.35910 -14.43365 22.62909  1.000 82.15658  ? 77  SER H OG  1 
ATOM   604  N N   . THR A 1 78  ? 17.16425 -12.89565 25.21654  1.000 80.53272  ? 78  THR H N   1 
ATOM   605  C CA  . THR A 1 78  ? 17.81580 -11.98266 26.14597  1.000 86.88351  ? 78  THR H CA  1 
ATOM   606  C C   . THR A 1 78  ? 19.10635 -11.45998 25.53332  1.000 84.03399  ? 78  THR H C   1 
ATOM   607  O O   . THR A 1 78  ? 19.89769 -12.23609 24.98773  1.000 93.38822  ? 78  THR H O   1 
ATOM   608  C CB  . THR A 1 78  ? 18.11696 -12.67265 27.48085  1.000 90.72380  ? 78  THR H CB  1 
ATOM   609  O OG1 . THR A 1 78  ? 16.95402 -13.37752 27.93296  1.000 85.31142  ? 78  THR H OG1 1 
ATOM   610  C CG2 . THR A 1 78  ? 18.52151 -11.64821 28.53030  1.000 97.95494  ? 78  THR H CG2 1 
ATOM   611  N N   . VAL A 1 79  ? 19.31391 -10.14858 25.62351  1.000 80.70316  ? 79  VAL H N   1 
ATOM   612  C CA  . VAL A 1 79  ? 20.56837 -9.51410  25.23676  1.000 83.82353  ? 79  VAL H CA  1 
ATOM   613  C C   . VAL A 1 79  ? 21.26501 -9.03173  26.50131  1.000 73.67723  ? 79  VAL H C   1 
ATOM   614  O O   . VAL A 1 79  ? 20.61288 -8.57987  27.45065  1.000 83.39439  ? 79  VAL H O   1 
ATOM   615  C CB  . VAL A 1 79  ? 20.35570 -8.35702  24.23699  1.000 83.80463  ? 79  VAL H CB  1 
ATOM   616  C CG1 . VAL A 1 79  ? 19.57165 -8.83481  23.02813  1.000 70.62769  ? 79  VAL H CG1 1 
ATOM   617  C CG2 . VAL A 1 79  ? 19.64503 -7.18591  24.89501  1.000 79.38961  ? 79  VAL H CG2 1 
ATOM   618  N N   . TYR A 1 80  ? 22.58781 -9.15741  26.52558  1.000 68.21717  ? 80  TYR H N   1 
ATOM   619  C CA  . TYR A 1 80  ? 23.38338 -8.78540  27.68328  1.000 77.46247  ? 80  TYR H CA  1 
ATOM   620  C C   . TYR A 1 80  ? 24.31169 -7.63079  27.33443  1.000 74.65488  ? 80  TYR H C   1 
ATOM   621  O O   . TYR A 1 80  ? 24.66127 -7.41167  26.17181  1.000 91.25867  ? 80  TYR H O   1 
ATOM   622  C CB  . TYR A 1 80  ? 24.20740 -9.97092  28.20437  1.000 89.62598  ? 80  TYR H CB  1 
ATOM   623  C CG  . TYR A 1 80  ? 23.39320 -11.20440 28.52345  1.000 93.23764  ? 80  TYR H CG  1 
ATOM   624  C CD1 . TYR A 1 80  ? 22.82674 -11.37980 29.77916  1.000 82.05270  ? 80  TYR H CD1 1 
ATOM   625  C CD2 . TYR A 1 80  ? 23.19802 -12.19749 27.57206  1.000 89.45649  ? 80  TYR H CD2 1 
ATOM   626  C CE1 . TYR A 1 80  ? 22.08442 -12.50724 30.07717  1.000 85.31112  ? 80  TYR H CE1 1 
ATOM   627  C CE2 . TYR A 1 80  ? 22.45721 -13.32827 27.86066  1.000 94.88957  ? 80  TYR H CE2 1 
ATOM   628  C CZ  . TYR A 1 80  ? 21.90313 -13.47784 29.11433  1.000 100.37203 ? 80  TYR H CZ  1 
ATOM   629  O OH  . TYR A 1 80  ? 21.16551 -14.60206 29.40549  1.000 111.64527 ? 80  TYR H OH  1 
ATOM   630  N N   . MET A 1 81  ? 24.70566 -6.88938  28.36800  1.000 81.56891  ? 81  MET H N   1 
ATOM   631  C CA  . MET A 1 81  ? 25.64429 -5.77547  28.23221  1.000 86.86027  ? 81  MET H CA  1 
ATOM   632  C C   . MET A 1 81  ? 26.57755 -5.82600  29.43712  1.000 82.54716  ? 81  MET H C   1 
ATOM   633  O O   . MET A 1 81  ? 26.18518 -5.45908  30.54907  1.000 78.28554  ? 81  MET H O   1 
ATOM   634  C CB  . MET A 1 81  ? 24.91772 -4.43909  28.14638  1.000 92.33276  ? 81  MET H CB  1 
ATOM   635  C CG  . MET A 1 81  ? 25.81064 -3.27501  27.74751  1.000 98.35917  ? 81  MET H CG  1 
ATOM   636  S SD  . MET A 1 81  ? 26.39474 -2.34537  29.17651  1.000 93.67839  ? 81  MET H SD  1 
ATOM   637  C CE  . MET A 1 81  ? 24.85898 -2.08730  30.06067  1.000 101.20215 ? 81  MET H CE  1 
ATOM   638  N N   . GLU A 1 82  ? 27.80719 -6.27820  29.21404  1.000 95.97810  ? 82  GLU H N   1 
ATOM   639  C CA  . GLU A 1 82  ? 28.78284 -6.46297  30.27839  1.000 95.41154  ? 82  GLU H CA  1 
ATOM   640  C C   . GLU A 1 82  ? 29.86940 -5.40252  30.17571  1.000 92.54781  ? 82  GLU H C   1 
ATOM   641  O O   . GLU A 1 82  ? 30.46829 -5.22003  29.11021  1.000 98.87813  ? 82  GLU H O   1 
ATOM   642  C CB  . GLU A 1 82  ? 29.40447 -7.85953  30.21579  1.000 106.72133 ? 82  GLU H CB  1 
ATOM   643  C CG  . GLU A 1 82  ? 30.24270 -8.21814  31.43207  1.000 97.04227  ? 82  GLU H CG  1 
ATOM   644  C CD  . GLU A 1 82  ? 31.52369 -8.93998  31.06536  1.000 104.58410 ? 82  GLU H CD  1 
ATOM   645  O OE1 . GLU A 1 82  ? 32.38292 -8.32489  30.39981  1.000 111.95547 ? 82  GLU H OE1 1 
ATOM   646  O OE2 . GLU A 1 82  ? 31.67041 -10.12302 31.43902  1.000 107.72456 ? 82  GLU H OE2 1 
ATOM   647  N N   . LEU A 1 83  ? 30.11934 -4.70909  31.28327  1.000 92.21309  ? 83  LEU H N   1 
ATOM   648  C CA  . LEU A 1 83  ? 31.21090 -3.74770  31.38508  1.000 97.94322  ? 83  LEU H CA  1 
ATOM   649  C C   . LEU A 1 83  ? 32.37338 -4.44092  32.08658  1.000 111.90384 ? 83  LEU H C   1 
ATOM   650  O O   . LEU A 1 83  ? 32.30149 -4.72379  33.28716  1.000 119.01019 ? 83  LEU H O   1 
ATOM   651  C CB  . LEU A 1 83  ? 30.77054 -2.49718  32.14287  1.000 88.80821  ? 83  LEU H CB  1 
ATOM   652  C CG  . LEU A 1 83  ? 29.57392 -1.74367  31.55706  1.000 98.23786  ? 83  LEU H CG  1 
ATOM   653  C CD1 . LEU A 1 83  ? 28.64086 -1.27007  32.66188  1.000 91.93690  ? 83  LEU H CD1 1 
ATOM   654  C CD2 . LEU A 1 83  ? 30.03123 -0.57677  30.69853  1.000 108.02036 ? 83  LEU H CD2 1 
ATOM   655  N N   . SER A 1 84  ? 33.43968 -4.72126  31.33239  1.000 109.82322 ? 84  SER H N   1 
ATOM   656  C CA  . SER A 1 84  ? 34.56491 -5.46872  31.88648  1.000 104.18467 ? 84  SER H CA  1 
ATOM   657  C C   . SER A 1 84  ? 35.22314 -4.71364  33.03404  1.000 111.69722 ? 84  SER H C   1 
ATOM   658  O O   . SER A 1 84  ? 35.56465 -5.30756  34.06386  1.000 103.72280 ? 84  SER H O   1 
ATOM   659  C CB  . SER A 1 84  ? 35.58464 -5.76949  30.78845  1.000 104.26553 ? 84  SER H CB  1 
ATOM   660  O OG  . SER A 1 84  ? 36.07609 -4.57281  30.21000  1.000 86.75223  ? 84  SER H OG  1 
ATOM   661  N N   . ARG A 1 85  ? 35.40850 -3.40687  32.87703  1.000 105.97929 ? 85  ARG H N   1 
ATOM   662  C CA  . ARG A 1 85  ? 36.01144 -2.56722  33.90013  1.000 94.34346  ? 85  ARG H CA  1 
ATOM   663  C C   . ARG A 1 85  ? 35.03587 -1.46152  34.27538  1.000 92.48483  ? 85  ARG H C   1 
ATOM   664  O O   . ARG A 1 85  ? 34.32683 -0.92891  33.41535  1.000 96.50873  ? 85  ARG H O   1 
ATOM   665  C CB  . ARG A 1 85  ? 37.33470 -1.97273  33.41280  1.000 104.52544 ? 85  ARG H CB  1 
ATOM   666  C CG  . ARG A 1 85  ? 38.35968 -1.74723  34.50977  1.000 94.21750  ? 85  ARG H CG  1 
ATOM   667  C CD  . ARG A 1 85  ? 39.76452 -1.71280  33.93239  1.000 101.90231 ? 85  ARG H CD  1 
ATOM   668  N NE  . ARG A 1 85  ? 40.30248 -3.05155  33.72246  1.000 103.42910 ? 85  ARG H NE  1 
ATOM   669  C CZ  . ARG A 1 85  ? 40.66465 -3.53856  32.54383  1.000 78.96864  ? 85  ARG H CZ  1 
ATOM   670  N NH1 . ARG A 1 85  ? 40.52644 -2.83399  31.43362  1.000 79.99796  ? 85  ARG H NH1 1 
ATOM   671  N NH2 . ARG A 1 85  ? 41.17286 -4.76592  32.47700  1.000 81.17415  ? 85  ARG H NH2 1 
ATOM   672  N N   . SER A 1 86  ? 35.00139 -1.12011  35.56090  1.000 84.09331  ? 86  SER H N   1 
ATOM   673  C CA  . SER A 1 86  ? 34.02379 -0.18245  36.09009  1.000 87.69854  ? 86  SER H CA  1 
ATOM   674  C C   . SER A 1 86  ? 34.72476 0.92764   36.86015  1.000 78.50237  ? 86  SER H C   1 
ATOM   675  O O   . SER A 1 86  ? 35.84475 0.76524   37.35138  1.000 71.15526  ? 86  SER H O   1 
ATOM   676  C CB  . SER A 1 86  ? 33.00486 -0.88886  36.99663  1.000 69.48693  ? 86  SER H CB  1 
ATOM   677  O OG  . SER A 1 86  ? 33.65486 -1.60210  38.03389  1.000 75.02021  ? 86  SER H OG  1 
ATOM   678  N N   . ARG A 1 87  ? 34.04277 2.06753   36.95488  1.000 78.16746  ? 87  ARG H N   1 
ATOM   679  C CA  . ARG A 1 87  ? 34.55097 3.23024   37.66542  1.000 77.12075  ? 87  ARG H CA  1 
ATOM   680  C C   . ARG A 1 87  ? 33.38869 3.93904   38.34646  1.000 86.61571  ? 87  ARG H C   1 
ATOM   681  O O   . ARG A 1 87  ? 32.21906 3.60441   38.13890  1.000 83.91231  ? 87  ARG H O   1 
ATOM   682  C CB  . ARG A 1 87  ? 35.29231 4.18768   36.72385  1.000 76.48423  ? 87  ARG H CB  1 
ATOM   683  C CG  . ARG A 1 87  ? 36.48529 4.87954   37.35934  1.000 98.95909  ? 87  ARG H CG  1 
ATOM   684  C CD  . ARG A 1 87  ? 36.70862 6.26560   36.77531  1.000 105.07573 ? 87  ARG H CD  1 
ATOM   685  N NE  . ARG A 1 87  ? 35.83622 7.26297   37.38419  1.000 122.77453 ? 87  ARG H NE  1 
ATOM   686  C CZ  . ARG A 1 87  ? 36.15127 7.98600   38.45037  1.000 111.20839 ? 87  ARG H CZ  1 
ATOM   687  N NH1 . ARG A 1 87  ? 37.31830 7.84915   39.05854  1.000 118.45954 ? 87  ARG H NH1 1 
ATOM   688  N NH2 . ARG A 1 87  ? 35.27284 8.86817   38.91858  1.000 90.08322  ? 87  ARG H NH2 1 
ATOM   689  N N   . SER A 1 88  ? 33.72665 4.93018   39.17512  1.000 91.54967  ? 88  SER H N   1 
ATOM   690  C CA  . SER A 1 88  ? 32.70200 5.67196   39.90350  1.000 87.69622  ? 88  SER H CA  1 
ATOM   691  C C   . SER A 1 88  ? 31.80636 6.46401   38.95779  1.000 95.49331  ? 88  SER H C   1 
ATOM   692  O O   . SER A 1 88  ? 30.60327 6.60348   39.20768  1.000 88.31292  ? 88  SER H O   1 
ATOM   693  C CB  . SER A 1 88  ? 33.35455 6.60067   40.92654  1.000 91.07648  ? 88  SER H CB  1 
ATOM   694  O OG  . SER A 1 88  ? 32.59579 7.78574   41.09302  1.000 109.48482 ? 88  SER H OG  1 
ATOM   695  N N   . ASP A 1 89  ? 32.37227 6.99428   37.86919  1.000 91.99230  ? 89  ASP H N   1 
ATOM   696  C CA  . ASP A 1 89  ? 31.58184 7.78112   36.92830  1.000 76.74225  ? 89  ASP H CA  1 
ATOM   697  C C   . ASP A 1 89  ? 30.56701 6.93672   36.16848  1.000 76.20082  ? 89  ASP H C   1 
ATOM   698  O O   . ASP A 1 89  ? 29.64681 7.49531   35.56184  1.000 69.16399  ? 89  ASP H O   1 
ATOM   699  C CB  . ASP A 1 89  ? 32.49702 8.50718   35.93809  1.000 76.30644  ? 89  ASP H CB  1 
ATOM   700  C CG  . ASP A 1 89  ? 33.54438 7.59368   35.32396  1.000 115.15998 ? 89  ASP H CG  1 
ATOM   701  O OD1 . ASP A 1 89  ? 33.30864 6.36949   35.24553  1.000 123.34722 ? 89  ASP H OD1 1 
ATOM   702  O OD2 . ASP A 1 89  ? 34.60771 8.10433   34.91238  1.000 115.62557 ? 89  ASP H OD2 1 
ATOM   703  N N   . ASP A 1 90  ? 30.71020 5.61111   36.18914  1.000 77.43408  ? 90  ASP H N   1 
ATOM   704  C CA  . ASP A 1 90  ? 29.77988 4.72979   35.49688  1.000 75.86554  ? 90  ASP H CA  1 
ATOM   705  C C   . ASP A 1 90  ? 28.47755 4.52579   36.25864  1.000 70.42174  ? 90  ASP H C   1 
ATOM   706  O O   . ASP A 1 90  ? 27.57021 3.87205   35.73264  1.000 74.16533  ? 90  ASP H O   1 
ATOM   707  C CB  . ASP A 1 90  ? 30.43973 3.37476   35.22795  1.000 69.06999  ? 90  ASP H CB  1 
ATOM   708  C CG  . ASP A 1 90  ? 31.62924 3.48161   34.29144  1.000 85.33481  ? 90  ASP H CG  1 
ATOM   709  O OD1 . ASP A 1 90  ? 31.72636 4.49207   33.56315  1.000 79.59090  ? 90  ASP H OD1 1 
ATOM   710  O OD2 . ASP A 1 90  ? 32.46759 2.55573   34.28315  1.000 88.03583  ? 90  ASP H OD2 1 
ATOM   711  N N   . THR A 1 91  ? 28.36607 5.05820   37.47602  1.000 68.40161  ? 91  THR H N   1 
ATOM   712  C CA  . THR A 1 91  ? 27.12041 4.99754   38.23094  1.000 72.03498  ? 91  THR H CA  1 
ATOM   713  C C   . THR A 1 91  ? 26.01117 5.72268   37.48095  1.000 71.71299  ? 91  THR H C   1 
ATOM   714  O O   . THR A 1 91  ? 26.03662 6.95225   37.36165  1.000 80.43358  ? 91  THR H O   1 
ATOM   715  C CB  . THR A 1 91  ? 27.30275 5.60612   39.62407  1.000 80.59846  ? 91  THR H CB  1 
ATOM   716  O OG1 . THR A 1 91  ? 28.27850 4.85283   40.35598  1.000 88.20999  ? 91  THR H OG1 1 
ATOM   717  C CG2 . THR A 1 91  ? 25.98406 5.61447   40.38502  1.000 61.45224  ? 91  THR H CG2 1 
ATOM   718  N N   . ALA A 1 92  ? 25.03530 4.97398   36.97917  1.000 66.83052  ? 92  ALA H N   1 
ATOM   719  C CA  . ALA A 1 92  ? 23.98201 5.53491   36.14023  1.000 60.13769  ? 92  ALA H CA  1 
ATOM   720  C C   . ALA A 1 92  ? 22.85317 4.51554   36.03825  1.000 62.35654  ? 92  ALA H C   1 
ATOM   721  O O   . ALA A 1 92  ? 22.93091 3.41265   36.58869  1.000 69.53851  ? 92  ALA H O   1 
ATOM   722  C CB  . ALA A 1 92  ? 24.52043 5.90958   34.75836  1.000 66.62873  ? 92  ALA H CB  1 
ATOM   723  N N   . VAL A 1 93  ? 21.79666 4.89999   35.32639  1.000 53.97178  ? 93  VAL H N   1 
ATOM   724  C CA  . VAL A 1 93  ? 20.68938 4.00995   34.99705  1.000 61.13486  ? 93  VAL H CA  1 
ATOM   725  C C   . VAL A 1 93  ? 20.83480 3.59601   33.54043  1.000 70.06516  ? 93  VAL H C   1 
ATOM   726  O O   . VAL A 1 93  ? 20.92055 4.45085   32.64956  1.000 77.98314  ? 93  VAL H O   1 
ATOM   727  C CB  . VAL A 1 93  ? 19.33151 4.68807   35.24492  1.000 62.77394  ? 93  VAL H CB  1 
ATOM   728  C CG1 . VAL A 1 93  ? 18.21611 3.65587   35.23964  1.000 66.11370  ? 93  VAL H CG1 1 
ATOM   729  C CG2 . VAL A 1 93  ? 19.35234 5.44900   36.55837  1.000 64.44057  ? 93  VAL H CG2 1 
ATOM   730  N N   . TYR A 1 94  ? 20.86206 2.29012   33.29488  1.000 70.96951  ? 94  TYR H N   1 
ATOM   731  C CA  . TYR A 1 94  ? 21.13276 1.74185   31.97321  1.000 62.56822  ? 94  TYR H CA  1 
ATOM   732  C C   . TYR A 1 94  ? 19.83998 1.22315   31.35985  1.000 71.26298  ? 94  TYR H C   1 
ATOM   733  O O   . TYR A 1 94  ? 19.13468 0.41693   31.97597  1.000 71.91931  ? 94  TYR H O   1 
ATOM   734  C CB  . TYR A 1 94  ? 22.17500 0.62406   32.05383  1.000 53.20300  ? 94  TYR H CB  1 
ATOM   735  C CG  . TYR A 1 94  ? 23.55514 1.11391   32.43365  1.000 57.70986  ? 94  TYR H CG  1 
ATOM   736  C CD1 . TYR A 1 94  ? 23.86486 1.41947   33.75347  1.000 70.18825  ? 94  TYR H CD1 1 
ATOM   737  C CD2 . TYR A 1 94  ? 24.54612 1.27540   31.47518  1.000 62.47063  ? 94  TYR H CD2 1 
ATOM   738  C CE1 . TYR A 1 94  ? 25.12141 1.87058   34.10824  1.000 65.12560  ? 94  TYR H CE1 1 
ATOM   739  C CE2 . TYR A 1 94  ? 25.80831 1.72580   31.82115  1.000 78.16664  ? 94  TYR H CE2 1 
ATOM   740  C CZ  . TYR A 1 94  ? 26.08944 2.02152   33.13977  1.000 75.68873  ? 94  TYR H CZ  1 
ATOM   741  O OH  . TYR A 1 94  ? 27.34163 2.47026   33.49372  1.000 67.01159  ? 94  TYR H OH  1 
ATOM   742  N N   . TYR A 1 95  ? 19.53829 1.68302   30.14847  1.000 72.41750  ? 95  TYR H N   1 
ATOM   743  C CA  . TYR A 1 95  ? 18.32057 1.31958   29.43875  1.000 72.86375  ? 95  TYR H CA  1 
ATOM   744  C C   . TYR A 1 95  ? 18.65556 0.49479   28.20362  1.000 67.23194  ? 95  TYR H C   1 
ATOM   745  O O   . TYR A 1 95  ? 19.67827 0.72377   27.54999  1.000 66.66459  ? 95  TYR H O   1 
ATOM   746  C CB  . TYR A 1 95  ? 17.53259 2.56522   29.01936  1.000 65.57626  ? 95  TYR H CB  1 
ATOM   747  C CG  . TYR A 1 95  ? 17.18093 3.50047   30.15365  1.000 69.96887  ? 95  TYR H CG  1 
ATOM   748  C CD1 . TYR A 1 95  ? 16.04486 3.29179   30.92434  1.000 79.20576  ? 95  TYR H CD1 1 
ATOM   749  C CD2 . TYR A 1 95  ? 17.98363 4.59364   30.45252  1.000 80.75209  ? 95  TYR H CD2 1 
ATOM   750  C CE1 . TYR A 1 95  ? 15.71751 4.14554   31.96158  1.000 84.31310  ? 95  TYR H CE1 1 
ATOM   751  C CE2 . TYR A 1 95  ? 17.66547 5.45240   31.48877  1.000 76.69157  ? 95  TYR H CE2 1 
ATOM   752  C CZ  . TYR A 1 95  ? 16.53151 5.22339   32.23959  1.000 80.89117  ? 95  TYR H CZ  1 
ATOM   753  O OH  . TYR A 1 95  ? 16.20997 6.07502   33.27156  1.000 88.91633  ? 95  TYR H OH  1 
ATOM   754  N N   . CYS A 1 96  ? 17.78998 -0.46509  27.89082  1.000 62.46576  ? 96  CYS H N   1 
ATOM   755  C CA  . CYS A 1 96  ? 17.85592 -1.21729  26.64555  1.000 75.44247  ? 96  CYS H CA  1 
ATOM   756  C C   . CYS A 1 96  ? 16.61911 -0.89384  25.81893  1.000 83.07872  ? 96  CYS H C   1 
ATOM   757  O O   . CYS A 1 96  ? 15.49606 -0.93126  26.33343  1.000 82.02550  ? 96  CYS H O   1 
ATOM   758  C CB  . CYS A 1 96  ? 17.95996 -2.72357  26.90587  1.000 72.85232  ? 96  CYS H CB  1 
ATOM   759  S SG  . CYS A 1 96  ? 16.56408 -3.45558  27.79167  1.000 98.85156  ? 96  CYS H SG  1 
ATOM   760  N N   . ALA A 1 97  ? 16.82708 -0.55967  24.54742  1.000 88.41411  ? 97  ALA H N   1 
ATOM   761  C CA  . ALA A 1 97  ? 15.75187 -0.10117  23.68080  1.000 78.74265  ? 97  ALA H CA  1 
ATOM   762  C C   . ALA A 1 97  ? 15.72040 -0.92050  22.40067  1.000 78.35205  ? 97  ALA H C   1 
ATOM   763  O O   . ALA A 1 97  ? 16.76647 -1.29203  21.86126  1.000 70.73731  ? 97  ALA H O   1 
ATOM   764  C CB  . ALA A 1 97  ? 15.90577 1.38513   23.34440  1.000 67.62473  ? 97  ALA H CB  1 
ATOM   765  N N   . ARG A 1 98  ? 14.51178 -1.18711  21.91749  1.000 77.22765  ? 98  ARG H N   1 
ATOM   766  C CA  . ARG A 1 98  ? 14.28939 -1.96526  20.70734  1.000 65.73683  ? 98  ARG H CA  1 
ATOM   767  C C   . ARG A 1 98  ? 14.08647 -1.02383  19.52730  1.000 75.76776  ? 98  ARG H C   1 
ATOM   768  O O   . ARG A 1 98  ? 13.35592 -0.03363  19.63519  1.000 66.18268  ? 98  ARG H O   1 
ATOM   769  C CB  . ARG A 1 98  ? 13.07886 -2.88377  20.88297  1.000 71.89961  ? 98  ARG H CB  1 
ATOM   770  C CG  . ARG A 1 98  ? 12.43009 -3.35458  19.59523  1.000 74.15235  ? 98  ARG H CG  1 
ATOM   771  C CD  . ARG A 1 98  ? 10.91991 -3.42367  19.76412  1.000 71.05900  ? 98  ARG H CD  1 
ATOM   772  N NE  . ARG A 1 98  ? 10.29433 -4.34408  18.82335  1.000 74.09153  ? 98  ARG H NE  1 
ATOM   773  C CZ  . ARG A 1 98  ? 9.07189  -4.19181  18.33361  1.000 81.45767  ? 98  ARG H CZ  1 
ATOM   774  N NH1 . ARG A 1 98  ? 8.31364  -3.16315  18.67667  1.000 75.77651  ? 98  ARG H NH1 1 
ATOM   775  N NH2 . ARG A 1 98  ? 8.59798  -5.09383  17.47885  1.000 99.35205  ? 98  ARG H NH2 1 
ATOM   776  N N   . ALA A 1 99  ? 14.74256 -1.32835  18.40916  1.000 80.60820  ? 99  ALA H N   1 
ATOM   777  C CA  . ALA A 1 99  ? 14.66558 -0.49243  17.21104  1.000 60.92791  ? 99  ALA H CA  1 
ATOM   778  C C   . ALA A 1 99  ? 13.54797 -0.98016  16.28617  1.000 74.24619  ? 99  ALA H C   1 
ATOM   779  O O   . ALA A 1 99  ? 13.76858 -1.40011  15.15077  1.000 80.92928  ? 99  ALA H O   1 
ATOM   780  C CB  . ALA A 1 99  ? 16.01247 -0.46972  16.49733  1.000 60.08688  ? 99  ALA H CB  1 
ATOM   781  N N   . GLY A 1 100 ? 12.32166 -0.90436  16.79921  1.000 71.52779  ? 100 GLY H N   1 
ATOM   782  C CA  . GLY A 1 100 ? 11.15103 -1.36827  16.08394  1.000 75.22921  ? 100 GLY H CA  1 
ATOM   783  C C   . GLY A 1 100 ? 10.56545 -0.40805  15.07586  1.000 82.55920  ? 100 GLY H C   1 
ATOM   784  O O   . GLY A 1 100 ? 9.56652  -0.73909  14.43101  1.000 83.03819  ? 100 GLY H O   1 
ATOM   785  N N   . LEU A 1 101 ? 11.15164 0.77658   14.91905  1.000 91.47681  ? 101 LEU H N   1 
ATOM   786  C CA  . LEU A 1 101 ? 10.66656 1.77226   13.96484  1.000 85.49748  ? 101 LEU H CA  1 
ATOM   787  C C   . LEU A 1 101 ? 11.37628 1.55020   12.63547  1.000 90.21905  ? 101 LEU H C   1 
ATOM   788  O O   . LEU A 1 101 ? 12.54132 1.91837   12.47073  1.000 88.01156  ? 101 LEU H O   1 
ATOM   789  C CB  . LEU A 1 101 ? 10.90333 3.18166   14.49257  1.000 91.33920  ? 101 LEU H CB  1 
ATOM   790  C CG  . LEU A 1 101 ? 9.95539  4.27373   13.99918  1.000 92.58355  ? 101 LEU H CG  1 
ATOM   791  C CD1 . LEU A 1 101 ? 8.55954  4.08836   14.57506  1.000 71.90639  ? 101 LEU H CD1 1 
ATOM   792  C CD2 . LEU A 1 101 ? 10.51535 5.63652   14.35732  1.000 101.00425 ? 101 LEU H CD2 1 
ATOM   793  N N   . GLU A 1 102 ? 10.67170 0.94799   11.68342  1.000 100.01935 ? 102 GLU H N   1 
ATOM   794  C CA  . GLU A 1 102 ? 11.26390 0.67711   10.38286  1.000 89.09101  ? 102 GLU H CA  1 
ATOM   795  C C   . GLU A 1 102 ? 11.48691 1.98167   9.61977   1.000 87.57311  ? 102 GLU H C   1 
ATOM   796  O O   . GLU A 1 102 ? 10.68487 2.91437   9.73297   1.000 99.03168  ? 102 GLU H O   1 
ATOM   797  C CB  . GLU A 1 102 ? 10.36679 -0.25557  9.57139   1.000 96.10050  ? 102 GLU H CB  1 
ATOM   798  C CG  . GLU A 1 102 ? 10.40909 -1.70409  10.02540  1.000 100.57718 ? 102 GLU H CG  1 
ATOM   799  C CD  . GLU A 1 102 ? 10.41873 -2.67686  8.86391   1.000 122.09593 ? 102 GLU H CD  1 
ATOM   800  O OE1 . GLU A 1 102 ? 9.44572  -2.67830  8.08073   1.000 122.93361 ? 102 GLU H OE1 1 
ATOM   801  O OE2 . GLU A 1 102 ? 11.39874 -3.44018  8.73395   1.000 131.12204 ? 102 GLU H OE2 1 
ATOM   802  N N   . PRO A 1 103 ? 12.56440 2.07962   8.83572   1.000 84.57975  ? 103 PRO H N   1 
ATOM   803  C CA  . PRO A 1 103 ? 12.78602 3.29106   8.03367   1.000 91.96394  ? 103 PRO H CA  1 
ATOM   804  C C   . PRO A 1 103 ? 11.81314 3.39635   6.87067   1.000 88.52426  ? 103 PRO H C   1 
ATOM   805  O O   . PRO A 1 103 ? 10.94180 2.53811   6.70135   1.000 92.82334  ? 103 PRO H O   1 
ATOM   806  C CB  . PRO A 1 103 ? 14.23059 3.12808   7.54447   1.000 83.67346  ? 103 PRO H CB  1 
ATOM   807  C CG  . PRO A 1 103 ? 14.45603 1.65314   7.54213   1.000 85.05675  ? 103 PRO H CG  1 
ATOM   808  C CD  . PRO A 1 103 ? 13.67228 1.11750   8.70769   1.000 84.22416  ? 103 PRO H CD  1 
ATOM   809  N N   . ARG A 1 104 ? 11.94827 4.44608   6.06492   1.000 93.49593  ? 104 ARG H N   1 
ATOM   810  C CA  . ARG A 1 104 ? 11.10250 4.63424   4.89487   1.000 89.33688  ? 104 ARG H CA  1 
ATOM   811  C C   . ARG A 1 104 ? 11.87204 4.77546   3.59185   1.000 73.03504  ? 104 ARG H C   1 
ATOM   812  O O   . ARG A 1 104 ? 11.35241 4.38352   2.54556   1.000 72.51126  ? 104 ARG H O   1 
ATOM   813  C CB  . ARG A 1 104 ? 10.20293 5.86821   5.07317   1.000 79.22361  ? 104 ARG H CB  1 
ATOM   814  C CG  . ARG A 1 104 ? 9.32154  5.81933   6.30961   1.000 100.50634 ? 104 ARG H CG  1 
ATOM   815  C CD  . ARG A 1 104 ? 7.91654  5.35077   5.95997   1.000 110.55026 ? 104 ARG H CD  1 
ATOM   816  N NE  . ARG A 1 104 ? 7.19700  4.85239   7.12619   1.000 128.39806 ? 104 ARG H NE  1 
ATOM   817  C CZ  . ARG A 1 104 ? 6.04378  4.19977   7.07251   1.000 130.08682 ? 104 ARG H CZ  1 
ATOM   818  N NH1 . ARG A 1 104 ? 5.44553  3.94670   5.91989   1.000 116.59473 ? 104 ARG H NH1 1 
ATOM   819  N NH2 . ARG A 1 104 ? 5.47656  3.79037   8.20373   1.000 148.53413 ? 104 ARG H NH2 1 
ATOM   820  N N   . SER A 1 105 ? 13.08919 5.31230   3.62205   1.000 74.51852  ? 105 SER H N   1 
ATOM   821  C CA  . SER A 1 105 ? 13.86917 5.54172   2.41631   1.000 79.28537  ? 105 SER H CA  1 
ATOM   822  C C   . SER A 1 105 ? 15.30231 5.07866   2.62940   1.000 75.50860  ? 105 SER H C   1 
ATOM   823  O O   . SER A 1 105 ? 15.80247 5.04869   3.75682   1.000 87.56107  ? 105 SER H O   1 
ATOM   824  C CB  . SER A 1 105 ? 13.85537 7.02384   2.01363   1.000 86.96468  ? 105 SER H CB  1 
ATOM   825  O OG  . SER A 1 105 ? 14.35989 7.20243   0.70189   1.000 84.24304  ? 105 SER H OG  1 
ATOM   826  N N   . VAL A 1 106 ? 15.95850 4.71191   1.52618   1.000 84.33460  ? 106 VAL H N   1 
ATOM   827  C CA  . VAL A 1 106 ? 17.35831 4.30700   1.59806   1.000 81.21802  ? 106 VAL H CA  1 
ATOM   828  C C   . VAL A 1 106 ? 18.24633 5.49159   1.95347   1.000 79.53106  ? 106 VAL H C   1 
ATOM   829  O O   . VAL A 1 106 ? 19.32721 5.31431   2.52848   1.000 94.24898  ? 106 VAL H O   1 
ATOM   830  C CB  . VAL A 1 106 ? 17.79604 3.65008   0.27656   1.000 85.04102  ? 106 VAL H CB  1 
ATOM   831  C CG1 . VAL A 1 106 ? 17.25207 2.23268   0.18564   1.000 84.91632  ? 106 VAL H CG1 1 
ATOM   832  C CG2 . VAL A 1 106 ? 17.33173 4.48191   -0.90866  1.000 81.73841  ? 106 VAL H CG2 1 
ATOM   833  N N   . ASP A 1 107 ? 17.82078 6.71124   1.61347   1.000 73.56606  ? 107 ASP H N   1 
ATOM   834  C CA  . ASP A 1 107 ? 18.58484 7.89646   1.98521   1.000 82.45102  ? 107 ASP H CA  1 
ATOM   835  C C   . ASP A 1 107 ? 18.63426 8.09745   3.49357   1.000 95.61067  ? 107 ASP H C   1 
ATOM   836  O O   . ASP A 1 107 ? 19.56285 8.74202   3.99320   1.000 100.66245 ? 107 ASP H O   1 
ATOM   837  C CB  . ASP A 1 107 ? 17.99342 9.14024   1.31647   1.000 95.35548  ? 107 ASP H CB  1 
ATOM   838  C CG  . ASP A 1 107 ? 17.55490 8.88453   -0.11451  1.000 103.05685 ? 107 ASP H CG  1 
ATOM   839  O OD1 . ASP A 1 107 ? 18.35517 8.32663   -0.89470  1.000 96.25709  ? 107 ASP H OD1 1 
ATOM   840  O OD2 . ASP A 1 107 ? 16.40959 9.24677   -0.46017  1.000 83.64624  ? 107 ASP H OD2 1 
ATOM   841  N N   . TYR A 1 108 ? 17.66105 7.56255   4.22549   1.000 99.32776  ? 108 TYR H N   1 
ATOM   842  C CA  . TYR A 1 108 ? 17.56180 7.70359   5.67480   1.000 94.10749  ? 108 TYR H CA  1 
ATOM   843  C C   . TYR A 1 108 ? 17.26700 6.35227   6.31340   1.000 91.52486  ? 108 TYR H C   1 
ATOM   844  O O   . TYR A 1 108 ? 16.36558 6.20199   7.14107   1.000 84.97147  ? 108 TYR H O   1 
ATOM   845  C CB  . TYR A 1 108 ? 16.49950 8.73734   6.03238   1.000 96.81978  ? 108 TYR H CB  1 
ATOM   846  C CG  . TYR A 1 108 ? 16.76130 10.09327  5.41665   1.000 104.90360 ? 108 TYR H CG  1 
ATOM   847  C CD1 . TYR A 1 108 ? 17.84483 10.86304  5.81987   1.000 108.65177 ? 108 TYR H CD1 1 
ATOM   848  C CD2 . TYR A 1 108 ? 15.93943 10.59303  4.41515   1.000 96.32778  ? 108 TYR H CD2 1 
ATOM   849  C CE1 . TYR A 1 108 ? 18.09238 12.10015  5.25484   1.000 96.94067  ? 108 TYR H CE1 1 
ATOM   850  C CE2 . TYR A 1 108 ? 16.18086 11.82749  3.84180   1.000 94.88452  ? 108 TYR H CE2 1 
ATOM   851  C CZ  . TYR A 1 108 ? 17.25701 12.57718  4.26681   1.000 100.24409 ? 108 TYR H CZ  1 
ATOM   852  O OH  . TYR A 1 108 ? 17.49975 13.80711  3.69985   1.000 118.35827 ? 108 TYR H OH  1 
ATOM   853  N N   . TYR A 1 109 ? 18.03922 5.33955   5.91704   1.000 84.47558  ? 109 TYR H N   1 
ATOM   854  C CA  . TYR A 1 109 ? 17.82325 3.95936   6.35156   1.000 83.54482  ? 109 TYR H CA  1 
ATOM   855  C C   . TYR A 1 109 ? 18.35139 3.78626   7.77393   1.000 84.95970  ? 109 TYR H C   1 
ATOM   856  O O   . TYR A 1 109 ? 19.47933 3.34611   8.01079   1.000 81.92891  ? 109 TYR H O   1 
ATOM   857  C CB  . TYR A 1 109 ? 18.49014 2.99084   5.38287   1.000 84.55876  ? 109 TYR H CB  1 
ATOM   858  C CG  . TYR A 1 109 ? 17.83179 1.63322   5.31575   1.000 78.65442  ? 109 TYR H CG  1 
ATOM   859  C CD1 . TYR A 1 109 ? 16.69688 1.42805   4.54313   1.000 87.75874  ? 109 TYR H CD1 1 
ATOM   860  C CD2 . TYR A 1 109 ? 18.35198 0.55356   6.01537   1.000 77.02919  ? 109 TYR H CD2 1 
ATOM   861  C CE1 . TYR A 1 109 ? 16.09239 0.18747   4.47730   1.000 83.81632  ? 109 TYR H CE1 1 
ATOM   862  C CE2 . TYR A 1 109 ? 17.75587 -0.69063  5.95443   1.000 80.85612  ? 109 TYR H CE2 1 
ATOM   863  C CZ  . TYR A 1 109 ? 16.62656 -0.86816  5.18437   1.000 75.88344  ? 109 TYR H CZ  1 
ATOM   864  O OH  . TYR A 1 109 ? 16.02899 -2.10570  5.12080   1.000 81.46346  ? 109 TYR H OH  1 
ATOM   865  N N   . PHE A 1 110 ? 17.50619 4.14180   8.74083   1.000 90.35441  ? 110 PHE H N   1 
ATOM   866  C CA  . PHE A 1 110 ? 17.79215 3.93905   10.15439  1.000 77.79777  ? 110 PHE H CA  1 
ATOM   867  C C   . PHE A 1 110 ? 16.56448 3.35952   10.84074  1.000 74.23954  ? 110 PHE H C   1 
ATOM   868  O O   . PHE A 1 110 ? 15.43069 3.71776   10.50879  1.000 70.48499  ? 110 PHE H O   1 
ATOM   869  C CB  . PHE A 1 110 ? 18.20253 5.24485   10.85083  1.000 73.06256  ? 110 PHE H CB  1 
ATOM   870  C CG  . PHE A 1 110 ? 19.08653 6.13048   10.01992  1.000 93.56266  ? 110 PHE H CG  1 
ATOM   871  C CD1 . PHE A 1 110 ? 20.42679 5.82595   9.84440   1.000 99.56798  ? 110 PHE H CD1 1 
ATOM   872  C CD2 . PHE A 1 110 ? 18.58255 7.27891   9.43122   1.000 93.64856  ? 110 PHE H CD2 1 
ATOM   873  C CE1 . PHE A 1 110 ? 21.24522 6.64269   9.08545   1.000 80.94270  ? 110 PHE H CE1 1 
ATOM   874  C CE2 . PHE A 1 110 ? 19.39615 8.10078   8.67305   1.000 94.68548  ? 110 PHE H CE2 1 
ATOM   875  C CZ  . PHE A 1 110 ? 20.72895 7.78160   8.49962   1.000 94.70010  ? 110 PHE H CZ  1 
ATOM   876  N N   . TYR A 1 111 ? 16.79503 2.46629   11.80110  1.000 70.88200  ? 111 TYR H N   1 
ATOM   877  C CA  . TYR A 1 111 ? 15.72392 1.84697   12.57486  1.000 77.14118  ? 111 TYR H CA  1 
ATOM   878  C C   . TYR A 1 111 ? 15.57594 2.60447   13.89059  1.000 82.02886  ? 111 TYR H C   1 
ATOM   879  O O   . TYR A 1 111 ? 16.40775 2.46386   14.79301  1.000 70.20981  ? 111 TYR H O   1 
ATOM   880  C CB  . TYR A 1 111 ? 16.01103 0.36691   12.81692  1.000 71.41500  ? 111 TYR H CB  1 
ATOM   881  C CG  . TYR A 1 111 ? 15.69163 -0.51745  11.63243  1.000 85.79366  ? 111 TYR H CG  1 
ATOM   882  C CD1 . TYR A 1 111 ? 16.57897 -0.63739  10.57049  1.000 76.27894  ? 111 TYR H CD1 1 
ATOM   883  C CD2 . TYR A 1 111 ? 14.50026 -1.22878  11.57389  1.000 97.28692  ? 111 TYR H CD2 1 
ATOM   884  C CE1 . TYR A 1 111 ? 16.29063 -1.44407  9.48609   1.000 67.46449  ? 111 TYR H CE1 1 
ATOM   885  C CE2 . TYR A 1 111 ? 14.20269 -2.03732  10.49299  1.000 79.63327  ? 111 TYR H CE2 1 
ATOM   886  C CZ  . TYR A 1 111 ? 15.10100 -2.14122  9.45256   1.000 82.60348  ? 111 TYR H CZ  1 
ATOM   887  O OH  . TYR A 1 111 ? 14.80793 -2.94561  8.37504   1.000 102.81801 ? 111 TYR H OH  1 
ATOM   888  N N   . GLY A 1 112 ? 14.50956 3.39561   14.00012  1.000 81.05627  ? 112 GLY H N   1 
ATOM   889  C CA  . GLY A 1 112 ? 14.32915 4.23714   15.16370  1.000 75.19305  ? 112 GLY H CA  1 
ATOM   890  C C   . GLY A 1 112 ? 13.98538 3.45214   16.41503  1.000 78.87081  ? 112 GLY H C   1 
ATOM   891  O O   . GLY A 1 112 ? 13.46943 2.33531   16.37233  1.000 77.18025  ? 112 GLY H O   1 
ATOM   892  N N   . LEU A 1 113 ? 14.27464 4.07140   17.55726  1.000 84.73267  ? 113 LEU H N   1 
ATOM   893  C CA  . LEU A 1 113 ? 14.06723 3.45836   18.86401  1.000 65.63166  ? 113 LEU H CA  1 
ATOM   894  C C   . LEU A 1 113 ? 12.66175 3.78709   19.35528  1.000 69.44965  ? 113 LEU H C   1 
ATOM   895  O O   . LEU A 1 113 ? 12.34380 4.95629   19.59896  1.000 76.52940  ? 113 LEU H O   1 
ATOM   896  C CB  . LEU A 1 113 ? 15.11517 3.95956   19.85778  1.000 53.17305  ? 113 LEU H CB  1 
ATOM   897  C CG  . LEU A 1 113 ? 16.46006 3.23258   19.94528  1.000 65.69792  ? 113 LEU H CG  1 
ATOM   898  C CD1 . LEU A 1 113 ? 17.22470 3.31131   18.63381  1.000 67.11823  ? 113 LEU H CD1 1 
ATOM   899  C CD2 . LEU A 1 113 ? 17.29252 3.82199   21.07083  1.000 79.46484  ? 113 LEU H CD2 1 
ATOM   900  N N   . ASP A 1 114 ? 11.82566 2.76288   19.50551  1.000 70.62711  ? 114 ASP H N   1 
ATOM   901  C CA  . ASP A 1 114 ? 10.43422 2.96632   19.89500  1.000 73.20147  ? 114 ASP H CA  1 
ATOM   902  C C   . ASP A 1 114 ? 10.06876 2.32231   21.22280  1.000 63.60443  ? 114 ASP H C   1 
ATOM   903  O O   . ASP A 1 114 ? 9.37123  2.94410   22.02795  1.000 66.27473  ? 114 ASP H O   1 
ATOM   904  C CB  . ASP A 1 114 ? 9.49292  2.44234   18.79651  1.000 71.37271  ? 114 ASP H CB  1 
ATOM   905  C CG  . ASP A 1 114 ? 9.65087  0.95464   18.54843  1.000 78.73692  ? 114 ASP H CG  1 
ATOM   906  O OD1 . ASP A 1 114 ? 10.73043 0.40883   18.85593  1.000 79.67238  ? 114 ASP H OD1 1 
ATOM   907  O OD2 . ASP A 1 114 ? 8.69318  0.33055   18.04517  1.000 78.82045  ? 114 ASP H OD2 1 
ATOM   908  N N   . VAL A 1 115 ? 10.51652 1.09699   21.48000  1.000 65.15893  ? 115 VAL H N   1 
ATOM   909  C CA  . VAL A 1 115 ? 10.17535 0.37342   22.69995  1.000 63.34339  ? 115 VAL H CA  1 
ATOM   910  C C   . VAL A 1 115 ? 11.38483 0.38994   23.62293  1.000 74.71401  ? 115 VAL H C   1 
ATOM   911  O O   . VAL A 1 115 ? 12.47285 -0.06153  23.24491  1.000 75.78617  ? 115 VAL H O   1 
ATOM   912  C CB  . VAL A 1 115 ? 9.73246  -1.06577  22.39613  1.000 68.44640  ? 115 VAL H CB  1 
ATOM   913  C CG1 . VAL A 1 115 ? 9.58434  -1.85638  23.68601  1.000 53.03116  ? 115 VAL H CG1 1 
ATOM   914  C CG2 . VAL A 1 115 ? 8.42726  -1.06217  21.61689  1.000 83.64535  ? 115 VAL H CG2 1 
ATOM   915  N N   . TRP A 1 116 ? 11.19365 0.90165   24.83412  1.000 74.31302  ? 116 TRP H N   1 
ATOM   916  C CA  . TRP A 1 116 ? 12.25447 1.02393   25.81980  1.000 74.24127  ? 116 TRP H CA  1 
ATOM   917  C C   . TRP A 1 116 ? 12.01470 0.06346   26.97673  1.000 78.89690  ? 116 TRP H C   1 
ATOM   918  O O   . TRP A 1 116 ? 10.91064 -0.45283  27.17082  1.000 83.57606  ? 116 TRP H O   1 
ATOM   919  C CB  . TRP A 1 116 ? 12.34722 2.45866   26.35013  1.000 65.65738  ? 116 TRP H CB  1 
ATOM   920  C CG  . TRP A 1 116 ? 12.87318 3.44063   25.35271  1.000 69.45781  ? 116 TRP H CG  1 
ATOM   921  C CD1 . TRP A 1 116 ? 12.25893 3.85463   24.20736  1.000 69.76243  ? 116 TRP H CD1 1 
ATOM   922  C CD2 . TRP A 1 116 ? 14.12169 4.13889   25.41353  1.000 66.65189  ? 116 TRP H CD2 1 
ATOM   923  N NE1 . TRP A 1 116 ? 13.04865 4.76608   23.54980  1.000 88.38137  ? 116 TRP H NE1 1 
ATOM   924  C CE2 . TRP A 1 116 ? 14.19815 4.95784   24.27016  1.000 78.63004  ? 116 TRP H CE2 1 
ATOM   925  C CE3 . TRP A 1 116 ? 15.18256 4.15022   26.32316  1.000 70.38905  ? 116 TRP H CE3 1 
ATOM   926  C CZ2 . TRP A 1 116 ? 15.29331 5.77917   24.01257  1.000 86.31972  ? 116 TRP H CZ2 1 
ATOM   927  C CZ3 . TRP A 1 116 ? 16.26751 4.96575   26.06594  1.000 69.45175  ? 116 TRP H CZ3 1 
ATOM   928  C CH2 . TRP A 1 116 ? 16.31555 5.76856   24.92052  1.000 76.00936  ? 116 TRP H CH2 1 
ATOM   929  N N   . GLY A 1 117 ? 13.07018 -0.16961  27.74729  1.000 71.09373  ? 117 GLY H N   1 
ATOM   930  C CA  . GLY A 1 117 ? 12.99129 -0.96617  28.95197  1.000 71.43597  ? 117 GLY H CA  1 
ATOM   931  C C   . GLY A 1 117 ? 12.55336 -0.13696  30.13982  1.000 84.75906  ? 117 GLY H C   1 
ATOM   932  O O   . GLY A 1 117 ? 11.92562 0.91599   30.00264  1.000 93.57737  ? 117 GLY H O   1 
ATOM   933  N N   . GLN A 1 118 ? 12.89208 -0.62764  31.33126  1.000 85.96703  ? 118 GLN H N   1 
ATOM   934  C CA  . GLN A 1 118 ? 12.58262 0.07470   32.56716  1.000 92.13059  ? 118 GLN H CA  1 
ATOM   935  C C   . GLN A 1 118 ? 13.80548 0.68378   33.23556  1.000 89.89584  ? 118 GLN H C   1 
ATOM   936  O O   . GLN A 1 118 ? 13.64673 1.52922   34.12302  1.000 85.40928  ? 118 GLN H O   1 
ATOM   937  C CB  . GLN A 1 118 ? 11.88289 -0.86868  33.55727  1.000 83.76480  ? 118 GLN H CB  1 
ATOM   938  C CG  . GLN A 1 118 ? 12.83003 -1.63104  34.46802  1.000 71.37846  ? 118 GLN H CG  1 
ATOM   939  C CD  . GLN A 1 118 ? 13.05904 -3.05493  34.00459  1.000 93.30146  ? 118 GLN H CD  1 
ATOM   940  O OE1 . GLN A 1 118 ? 12.65139 -3.43541  32.90709  1.000 92.30209  ? 118 GLN H OE1 1 
ATOM   941  N NE2 . GLN A 1 118 ? 13.71200 -3.85243  34.84193  1.000 97.60991  ? 118 GLN H NE2 1 
ATOM   942  N N   . GLY A 1 119 ? 15.00291 0.28953   32.83730  1.000 89.16735  ? 119 GLY H N   1 
ATOM   943  C CA  . GLY A 1 119 ? 16.21836 0.81226   33.42416  1.000 78.46844  ? 119 GLY H CA  1 
ATOM   944  C C   . GLY A 1 119 ? 16.79801 -0.12291  34.46764  1.000 70.30034  ? 119 GLY H C   1 
ATOM   945  O O   . GLY A 1 119 ? 16.08884 -0.90615  35.10952  1.000 74.01975  ? 119 GLY H O   1 
ATOM   946  N N   . THR A 1 120 ? 18.11571 -0.04597  34.63840  1.000 69.50672  ? 120 THR H N   1 
ATOM   947  C CA  . THR A 1 120 ? 18.82967 -0.82802  35.63993  1.000 71.84791  ? 120 THR H CA  1 
ATOM   948  C C   . THR A 1 120 ? 19.72474 0.11150   36.43061  1.000 70.59153  ? 120 THR H C   1 
ATOM   949  O O   . THR A 1 120 ? 20.59604 0.77190   35.85524  1.000 62.72602  ? 120 THR H O   1 
ATOM   950  C CB  . THR A 1 120 ? 19.65697 -1.94289  34.99378  1.000 81.18339  ? 120 THR H CB  1 
ATOM   951  O OG1 . THR A 1 120 ? 18.78159 -2.88626  34.36352  1.000 80.92614  ? 120 THR H OG1 1 
ATOM   952  C CG2 . THR A 1 120 ? 20.49646 -2.65844  36.04130  1.000 80.89174  ? 120 THR H CG2 1 
ATOM   953  N N   . ALA A 1 121 ? 19.51201 0.16858   37.74283  1.000 80.87965  ? 121 ALA H N   1 
ATOM   954  C CA  . ALA A 1 121 ? 20.27036 1.06551   38.60752  1.000 77.58179  ? 121 ALA H CA  1 
ATOM   955  C C   . ALA A 1 121 ? 21.61565 0.42720   38.92662  1.000 80.39176  ? 121 ALA H C   1 
ATOM   956  O O   . ALA A 1 121 ? 21.69064 -0.52302  39.71246  1.000 85.96550  ? 121 ALA H O   1 
ATOM   957  C CB  . ALA A 1 121 ? 19.48763 1.36767   39.88165  1.000 77.55669  ? 121 ALA H CB  1 
ATOM   958  N N   . VAL A 1 122 ? 22.67747 0.94436   38.31772  1.000 75.08114  ? 122 VAL H N   1 
ATOM   959  C CA  . VAL A 1 122 ? 24.03505 0.47049   38.55410  1.000 78.35953  ? 122 VAL H CA  1 
ATOM   960  C C   . VAL A 1 122 ? 24.76909 1.56057   39.32080  1.000 78.17004  ? 122 VAL H C   1 
ATOM   961  O O   . VAL A 1 122 ? 25.00426 2.65506   38.79425  1.000 66.57821  ? 122 VAL H O   1 
ATOM   962  C CB  . VAL A 1 122 ? 24.75797 0.12244   37.24630  1.000 64.94659  ? 122 VAL H CB  1 
ATOM   963  C CG1 . VAL A 1 122 ? 26.23871 -0.11168  37.50506  1.000 54.85520  ? 122 VAL H CG1 1 
ATOM   964  C CG2 . VAL A 1 122 ? 24.12614 -1.10187  36.60426  1.000 69.72298  ? 122 VAL H CG2 1 
ATOM   965  N N   . THR A 1 123 ? 25.12435 1.26506   40.56787  1.000 74.16764  ? 123 THR H N   1 
ATOM   966  C CA  . THR A 1 123 ? 25.86405 2.17962   41.43130  1.000 75.70549  ? 123 THR H CA  1 
ATOM   967  C C   . THR A 1 123 ? 27.18974 1.51741   41.77213  1.000 74.69238  ? 123 THR H C   1 
ATOM   968  O O   . THR A 1 123 ? 27.22015 0.55984   42.55280  1.000 86.16291  ? 123 THR H O   1 
ATOM   969  C CB  . THR A 1 123 ? 25.07477 2.49526   42.70234  1.000 68.74075  ? 123 THR H CB  1 
ATOM   970  O OG1 . THR A 1 123 ? 23.78321 3.00967   42.35483  1.000 84.41221  ? 123 THR H OG1 1 
ATOM   971  C CG2 . THR A 1 123 ? 25.81495 3.51497   43.55431  1.000 68.12339  ? 123 THR H CG2 1 
ATOM   972  N N   . VAL A 1 124 ? 28.28838 2.00752   41.19688  1.000 76.67260  ? 124 VAL H N   1 
ATOM   973  C CA  . VAL A 1 124 ? 29.54399 1.32546   41.47652  1.000 84.74638  ? 124 VAL H CA  1 
ATOM   974  C C   . VAL A 1 124 ? 30.16380 1.90108   42.74372  1.000 94.33938  ? 124 VAL H C   1 
ATOM   975  O O   . VAL A 1 124 ? 30.00342 1.32377   43.82427  1.000 111.58188 ? 124 VAL H O   1 
ATOM   976  C CB  . VAL A 1 124 ? 30.51047 1.44197   40.28261  1.000 90.95922  ? 124 VAL H CB  1 
ATOM   977  C CG1 . VAL A 1 124 ? 31.77074 0.62603   40.53069  1.000 89.83637  ? 124 VAL H CG1 1 
ATOM   978  C CG2 . VAL A 1 124 ? 29.82207 1.00639   38.99333  1.000 80.47159  ? 124 VAL H CG2 1 
ATOM   979  N N   . SER A 1 125 ? 30.80655 3.07094   42.63365  1.000 91.85572  ? 125 SER H N   1 
ATOM   980  C CA  . SER A 1 125 ? 31.22485 3.90617   43.76269  1.000 124.23247 ? 125 SER H CA  1 
ATOM   981  C C   . SER A 1 125 ? 31.56220 3.10107   45.01737  1.000 114.20174 ? 125 SER H C   1 
ATOM   982  O O   . SER A 1 125 ? 31.07714 3.41843   46.10843  1.000 84.81598  ? 125 SER H O   1 
ATOM   983  C CB  . SER A 1 125 ? 30.15183 4.95379   44.06388  1.000 127.16549 ? 125 SER H CB  1 
ATOM   984  O OG  . SER A 1 125 ? 29.97634 5.81838   42.95287  1.000 119.99262 ? 125 SER H OG  1 
ATOM   985  N N   . GLY A 1 126 ? 32.38822 2.06597   44.87701  1.000 101.65818 ? 126 GLY H N   1 
ATOM   986  C CA  . GLY A 1 126 ? 32.48844 1.02784   45.88845  1.000 84.70361  ? 126 GLY H CA  1 
ATOM   987  C C   . GLY A 1 126 ? 33.02179 1.44084   47.24524  1.000 106.56992 ? 126 GLY H C   1 
ATOM   988  O O   . GLY A 1 126 ? 34.20457 1.76366   47.38689  1.000 112.06692 ? 126 GLY H O   1 
ATOM   989  N N   . ALA A 1 127 ? 32.15333 1.41887   48.25555  1.000 103.98394 ? 127 ALA H N   1 
ATOM   990  C CA  . ALA A 1 127 ? 32.53622 1.70083   49.63075  1.000 79.09613  ? 127 ALA H CA  1 
ATOM   991  C C   . ALA A 1 127 ? 31.76371 0.77559   50.56133  1.000 99.86145  ? 127 ALA H C   1 
ATOM   992  O O   . ALA A 1 127 ? 30.87371 0.03211   50.13912  1.000 94.32341  ? 127 ALA H O   1 
ATOM   993  C CB  . ALA A 1 127 ? 32.28791 3.16964   49.99804  1.000 76.01064  ? 127 ALA H CB  1 
ATOM   994  N N   . SER A 1 128 ? 32.11273 0.83042   51.84301  1.000 109.20717 ? 128 SER H N   1 
ATOM   995  C CA  . SER A 1 128 ? 31.48329 0.01856   52.87248  1.000 80.00418  ? 128 SER H CA  1 
ATOM   996  C C   . SER A 1 128 ? 30.67709 0.90375   53.81400  1.000 78.75772  ? 128 SER H C   1 
ATOM   997  O O   . SER A 1 128 ? 30.82145 2.12930   53.82356  1.000 86.55111  ? 128 SER H O   1 
ATOM   998  C CB  . SER A 1 128 ? 32.52908 -0.77632  53.66240  1.000 61.46259  ? 128 SER H CB  1 
ATOM   999  O OG  . SER A 1 128 ? 31.92231 -1.82364  54.39869  1.000 89.99611  ? 128 SER H OG  1 
ATOM   1000 N N   . THR A 1 129 ? 29.81692 0.26275   54.60544  1.000 85.06261  ? 129 THR H N   1 
ATOM   1001 C CA  . THR A 1 129 ? 28.95386 0.98592   55.53327  1.000 81.59672  ? 129 THR H CA  1 
ATOM   1002 C C   . THR A 1 129 ? 29.78612 1.81746   56.50092  1.000 81.04314  ? 129 THR H C   1 
ATOM   1003 O O   . THR A 1 129 ? 30.65293 1.28913   57.20401  1.000 82.86330  ? 129 THR H O   1 
ATOM   1004 C CB  . THR A 1 129 ? 28.06566 0.00621   56.29878  1.000 89.49027  ? 129 THR H CB  1 
ATOM   1005 O OG1 . THR A 1 129 ? 27.26086 -0.73282  55.37152  1.000 89.29771  ? 129 THR H OG1 1 
ATOM   1006 C CG2 . THR A 1 129 ? 27.15762 0.75240   57.26510  1.000 88.74101  ? 129 THR H CG2 1 
ATOM   1007 N N   . LYS A 1 130 ? 29.51631 3.12065   56.53620  1.000 80.07213  ? 130 LYS H N   1 
ATOM   1008 C CA  . LYS A 1 130 ? 30.31229 4.06159   57.30874  1.000 75.74679  ? 130 LYS H CA  1 
ATOM   1009 C C   . LYS A 1 130 ? 29.39810 5.02773   58.04536  1.000 88.79200  ? 130 LYS H C   1 
ATOM   1010 O O   . LYS A 1 130 ? 28.35780 5.43427   57.51996  1.000 71.96034  ? 130 LYS H O   1 
ATOM   1011 C CB  . LYS A 1 130 ? 31.27779 4.83665   56.40268  1.000 72.45975  ? 130 LYS H CB  1 
ATOM   1012 C CG  . LYS A 1 130 ? 32.41192 5.52727   57.13555  1.000 76.86861  ? 130 LYS H CG  1 
ATOM   1013 C CD  . LYS A 1 130 ? 32.98615 6.66123   56.30182  1.000 72.93390  ? 130 LYS H CD  1 
ATOM   1014 C CE  . LYS A 1 130 ? 33.76854 7.64090   57.15949  1.000 91.88724  ? 130 LYS H CE  1 
ATOM   1015 N NZ  . LYS A 1 130 ? 32.87110 8.46529   58.01565  1.000 73.55424  ? 130 LYS H NZ  1 
ATOM   1016 N N   . GLY A 1 131 ? 29.79348 5.38941   59.26386  1.000 103.78308 ? 131 GLY H N   1 
ATOM   1017 C CA  . GLY A 1 131 ? 29.05231 6.33891   60.05779  1.000 84.80834  ? 131 GLY H CA  1 
ATOM   1018 C C   . GLY A 1 131 ? 29.24353 7.76242   59.57561  1.000 89.25728  ? 131 GLY H C   1 
ATOM   1019 O O   . GLY A 1 131 ? 30.27123 8.11254   58.98644  1.000 93.04442  ? 131 GLY H O   1 
ATOM   1020 N N   . PRO A 1 132 ? 28.25162 8.61551   59.82169  1.000 83.76541  ? 132 PRO H N   1 
ATOM   1021 C CA  . PRO A 1 132 ? 28.34236 10.00481  59.36208  1.000 82.56743  ? 132 PRO H CA  1 
ATOM   1022 C C   . PRO A 1 132 ? 29.14877 10.87157  60.31592  1.000 79.27568  ? 132 PRO H C   1 
ATOM   1023 O O   . PRO A 1 132 ? 29.07250 10.72881  61.53889  1.000 85.68665  ? 132 PRO H O   1 
ATOM   1024 C CB  . PRO A 1 132 ? 26.87700 10.45128  59.31690  1.000 74.47403  ? 132 PRO H CB  1 
ATOM   1025 C CG  . PRO A 1 132 ? 26.21959 9.64570   60.38609  1.000 83.27503  ? 132 PRO H CG  1 
ATOM   1026 C CD  . PRO A 1 132 ? 26.96130 8.32933   60.47319  1.000 91.20907  ? 132 PRO H CD  1 
ATOM   1027 N N   . SER A 1 133 ? 29.92947 11.77981  59.73794  1.000 76.43217  ? 133 SER H N   1 
ATOM   1028 C CA  . SER A 1 133 ? 30.66648 12.78308  60.49471  1.000 76.28259  ? 133 SER H CA  1 
ATOM   1029 C C   . SER A 1 133 ? 29.91392 14.10433  60.40084  1.000 84.46899  ? 133 SER H C   1 
ATOM   1030 O O   . SER A 1 133 ? 29.78012 14.67030  59.31029  1.000 92.25839  ? 133 SER H O   1 
ATOM   1031 C CB  . SER A 1 133 ? 32.09307 12.93233  59.96687  1.000 76.65220  ? 133 SER H CB  1 
ATOM   1032 O OG  . SER A 1 133 ? 32.83370 11.73903  60.15423  1.000 94.93455  ? 133 SER H OG  1 
ATOM   1033 N N   . VAL A 1 134 ? 29.42776 14.59166  61.53804  1.000 84.84904  ? 134 VAL H N   1 
ATOM   1034 C CA  . VAL A 1 134 ? 28.58622 15.78151  61.58981  1.000 83.05227  ? 134 VAL H CA  1 
ATOM   1035 C C   . VAL A 1 134 ? 29.43649 16.96484  62.02803  1.000 91.33928  ? 134 VAL H C   1 
ATOM   1036 O O   . VAL A 1 134 ? 30.06279 16.93200  63.09444  1.000 95.43159  ? 134 VAL H O   1 
ATOM   1037 C CB  . VAL A 1 134 ? 27.38993 15.58224  62.53249  1.000 75.40908  ? 134 VAL H CB  1 
ATOM   1038 C CG1 . VAL A 1 134 ? 26.41788 16.74358  62.40356  1.000 96.53295  ? 134 VAL H CG1 1 
ATOM   1039 C CG2 . VAL A 1 134 ? 26.69280 14.27031  62.22054  1.000 69.77170  ? 134 VAL H CG2 1 
ATOM   1040 N N   . PHE A 1 135 ? 29.45304 18.01266  61.20491  1.000 83.32433  ? 135 PHE H N   1 
ATOM   1041 C CA  . PHE A 1 135 ? 30.15197 19.24961  61.49346  1.000 87.99642  ? 135 PHE H CA  1 
ATOM   1042 C C   . PHE A 1 135 ? 29.16719 20.41194  61.50013  1.000 89.85972  ? 135 PHE H C   1 
ATOM   1043 O O   . PHE A 1 135 ? 28.27025 20.46643  60.65204  1.000 94.65819  ? 135 PHE H O   1 
ATOM   1044 C CB  . PHE A 1 135 ? 31.25587 19.51451  60.45927  1.000 84.39660  ? 135 PHE H CB  1 
ATOM   1045 C CG  . PHE A 1 135 ? 32.23959 18.38833  60.32322  1.000 76.51241  ? 135 PHE H CG  1 
ATOM   1046 C CD1 . PHE A 1 135 ? 33.10187 18.07572  61.36057  1.000 78.94437  ? 135 PHE H CD1 1 
ATOM   1047 C CD2 . PHE A 1 135 ? 32.29858 17.63864  59.16035  1.000 75.84683  ? 135 PHE H CD2 1 
ATOM   1048 C CE1 . PHE A 1 135 ? 34.00793 17.03859  61.23922  1.000 93.44369  ? 135 PHE H CE1 1 
ATOM   1049 C CE2 . PHE A 1 135 ? 33.20205 16.60012  59.03281  1.000 82.75092  ? 135 PHE H CE2 1 
ATOM   1050 C CZ  . PHE A 1 135 ? 34.05766 16.29969  60.07360  1.000 83.76551  ? 135 PHE H CZ  1 
ATOM   1051 N N   . PRO A 1 136 ? 29.30279 21.35135  62.43487  1.000 92.24062  ? 136 PRO H N   1 
ATOM   1052 C CA  . PRO A 1 136 ? 28.29718 22.41292  62.55674  1.000 92.70152  ? 136 PRO H CA  1 
ATOM   1053 C C   . PRO A 1 136 ? 28.56260 23.60655  61.65281  1.000 84.68172  ? 136 PRO H C   1 
ATOM   1054 O O   . PRO A 1 136 ? 29.64516 24.19949  61.68902  1.000 87.68739  ? 136 PRO H O   1 
ATOM   1055 C CB  . PRO A 1 136 ? 28.38554 22.80161  64.03773  1.000 83.54732  ? 136 PRO H CB  1 
ATOM   1056 C CG  . PRO A 1 136 ? 29.78703 22.41329  64.46583  1.000 87.07200  ? 136 PRO H CG  1 
ATOM   1057 C CD  . PRO A 1 136 ? 30.38997 21.50815  63.41508  1.000 97.08530  ? 136 PRO H CD  1 
ATOM   1058 N N   . LEU A 1 137 ? 27.57535 23.96545  60.83645  1.000 76.48312  ? 137 LEU H N   1 
ATOM   1059 C CA  . LEU A 1 137 ? 27.62285 25.20129  60.05921  1.000 91.30394  ? 137 LEU H CA  1 
ATOM   1060 C C   . LEU A 1 137 ? 27.14485 26.32926  60.96271  1.000 84.41514  ? 137 LEU H C   1 
ATOM   1061 O O   . LEU A 1 137 ? 25.94094 26.53335  61.14086  1.000 81.05211  ? 137 LEU H O   1 
ATOM   1062 C CB  . LEU A 1 137 ? 26.76237 25.08865  58.80736  1.000 86.08903  ? 137 LEU H CB  1 
ATOM   1063 C CG  . LEU A 1 137 ? 26.93247 23.81614  57.97779  1.000 68.56932  ? 137 LEU H CG  1 
ATOM   1064 C CD1 . LEU A 1 137 ? 25.83034 23.70878  56.93502  1.000 67.08630  ? 137 LEU H CD1 1 
ATOM   1065 C CD2 . LEU A 1 137 ? 28.30412 23.77609  57.32650  1.000 64.86904  ? 137 LEU H CD2 1 
ATOM   1066 N N   . ALA A 1 138 ? 28.09259 27.06952  61.53119  1.000 86.95697  ? 138 ALA H N   1 
ATOM   1067 C CA  . ALA A 1 138 ? 27.76324 28.04748  62.55256  1.000 101.79206 ? 138 ALA H CA  1 
ATOM   1068 C C   . ALA A 1 138 ? 26.93379 29.19191  61.97431  1.000 111.35353 ? 138 ALA H C   1 
ATOM   1069 O O   . ALA A 1 138 ? 27.10283 29.57601  60.81381  1.000 100.04393 ? 138 ALA H O   1 
ATOM   1070 C CB  . ALA A 1 138 ? 29.03167 28.60687  63.19032  1.000 98.18993  ? 138 ALA H CB  1 
ATOM   1071 N N   . PRO A 1 139 ? 26.02694 29.75454  62.77111  1.000 110.16728 ? 139 PRO H N   1 
ATOM   1072 C CA  . PRO A 1 139 ? 25.29622 30.95666  62.35969  1.000 109.99084 ? 139 PRO H CA  1 
ATOM   1073 C C   . PRO A 1 139 ? 26.11908 32.23409  62.39194  1.000 129.11196 ? 139 PRO H C   1 
ATOM   1074 O O   . PRO A 1 139 ? 25.54851 33.31779  62.24895  1.000 141.68834 ? 139 PRO H O   1 
ATOM   1075 C CB  . PRO A 1 139 ? 24.15459 31.01917  63.38661  1.000 86.08360  ? 139 PRO H CB  1 
ATOM   1076 C CG  . PRO A 1 139 ? 24.69442 30.30996  64.59198  1.000 95.06171  ? 139 PRO H CG  1 
ATOM   1077 C CD  . PRO A 1 139 ? 25.56397 29.21937  64.06244  1.000 95.41988  ? 139 PRO H CD  1 
ATOM   1078 N N   . SER A 1 140 ? 27.43394 32.13354  62.55713  1.000 142.26807 ? 140 SER H N   1 
ATOM   1079 C CA  . SER A 1 140 ? 28.29093 33.29987  62.69089  1.000 154.61620 ? 140 SER H CA  1 
ATOM   1080 C C   . SER A 1 140 ? 28.36702 34.05696  61.36562  1.000 151.68317 ? 140 SER H C   1 
ATOM   1081 O O   . SER A 1 140 ? 27.72938 33.69783  60.37098  1.000 123.09212 ? 140 SER H O   1 
ATOM   1082 C CB  . SER A 1 140 ? 29.68336 32.88477  63.16505  1.000 147.42544 ? 140 SER H CB  1 
ATOM   1083 O OG  . SER A 1 140 ? 30.58714 32.82027  62.07871  1.000 158.03774 ? 140 SER H OG  1 
ATOM   1084 N N   . SER A 1 141 ? 29.15003 35.14010  61.37181  1.000 154.77616 ? 141 SER H N   1 
ATOM   1085 C CA  . SER A 1 141 ? 29.28560 36.04819  60.23583  1.000 154.52273 ? 141 SER H CA  1 
ATOM   1086 C C   . SER A 1 141 ? 27.95268 36.71866  59.92251  1.000 151.36902 ? 141 SER H C   1 
ATOM   1087 O O   . SER A 1 141 ? 26.96080 36.51119  60.62921  1.000 143.55389 ? 141 SER H O   1 
ATOM   1088 C CB  . SER A 1 141 ? 29.82558 35.31588  59.00154  1.000 157.41709 ? 141 SER H CB  1 
ATOM   1089 O OG  . SER A 1 141 ? 31.21751 35.06743  59.11262  1.000 142.34738 ? 141 SER H OG  1 
ATOM   1090 N N   . LYS A 1 142 ? 27.91846 37.53167  58.86809  1.000 158.55624 ? 142 LYS H N   1 
ATOM   1091 C CA  . LYS A 1 142 ? 26.71983 38.29540  58.52298  1.000 159.00605 ? 142 LYS H CA  1 
ATOM   1092 C C   . LYS A 1 142 ? 25.75142 37.38545  57.76988  1.000 167.29312 ? 142 LYS H C   1 
ATOM   1093 O O   . LYS A 1 142 ? 25.70756 37.33908  56.53690  1.000 164.63211 ? 142 LYS H O   1 
ATOM   1094 C CB  . LYS A 1 142 ? 27.08572 39.53103  57.71080  1.000 154.57226 ? 142 LYS H CB  1 
ATOM   1095 C CG  . LYS A 1 142 ? 27.23248 40.81113  58.53434  1.000 151.84140 ? 142 LYS H CG  1 
ATOM   1096 C CD  . LYS A 1 142 ? 27.89610 40.55925  59.88223  1.000 145.34529 ? 142 LYS H CD  1 
ATOM   1097 C CE  . LYS A 1 142 ? 28.11984 41.85867  60.64163  1.000 140.02491 ? 142 LYS H CE  1 
ATOM   1098 N NZ  . LYS A 1 142 ? 26.84218 42.45233  61.12275  1.000 136.62501 ? 142 LYS H NZ  1 
ATOM   1099 N N   . SER A 1 143 ? 24.95304 36.64690  58.54302  1.000 163.38960 ? 143 SER H N   1 
ATOM   1100 C CA  . SER A 1 143 ? 23.91660 35.77311  58.00709  1.000 158.36028 ? 143 SER H CA  1 
ATOM   1101 C C   . SER A 1 143 ? 22.51695 36.31106  58.28233  1.000 155.74293 ? 143 SER H C   1 
ATOM   1102 O O   . SER A 1 143 ? 21.55296 35.53916  58.31683  1.000 148.94328 ? 143 SER H O   1 
ATOM   1103 C CB  . SER A 1 143 ? 24.06145 34.36177  58.57840  1.000 135.20789 ? 143 SER H CB  1 
ATOM   1104 O OG  . SER A 1 143 ? 25.16119 33.68234  57.99890  1.000 146.27266 ? 143 SER H OG  1 
ATOM   1105 N N   . THR A 1 144 ? 22.38795 37.62088  58.47751  1.000 157.42861 ? 144 THR H N   1 
ATOM   1106 C CA  . THR A 1 144 ? 21.12636 38.24340  58.86014  1.000 152.44127 ? 144 THR H CA  1 
ATOM   1107 C C   . THR A 1 144 ? 20.46881 38.85487  57.62790  1.000 157.96484 ? 144 THR H C   1 
ATOM   1108 O O   . THR A 1 144 ? 20.92819 39.87939  57.11276  1.000 164.43934 ? 144 THR H O   1 
ATOM   1109 C CB  . THR A 1 144 ? 21.34981 39.30085  59.93984  1.000 157.71961 ? 144 THR H CB  1 
ATOM   1110 O OG1 . THR A 1 144 ? 22.46645 40.12620  59.58261  1.000 157.35658 ? 144 THR H OG1 1 
ATOM   1111 C CG2 . THR A 1 144 ? 21.62212 38.64021  61.28381  1.000 150.71271 ? 144 THR H CG2 1 
ATOM   1112 N N   . SER A 1 145 ? 19.39295 38.22451  57.15843  1.000 161.14139 ? 145 SER H N   1 
ATOM   1113 C CA  . SER A 1 145 ? 18.53116 38.80427  56.13694  1.000 164.64227 ? 145 SER H CA  1 
ATOM   1114 C C   . SER A 1 145 ? 17.46980 39.72287  56.73453  1.000 156.83589 ? 145 SER H C   1 
ATOM   1115 O O   . SER A 1 145 ? 16.47864 40.04806  56.06916  1.000 155.95726 ? 145 SER H O   1 
ATOM   1116 C CB  . SER A 1 145 ? 17.87562 37.69291  55.31160  1.000 153.96699 ? 145 SER H CB  1 
ATOM   1117 O OG  . SER A 1 145 ? 17.63307 38.10982  53.97927  1.000 139.39904 ? 145 SER H OG  1 
ATOM   1118 N N   . GLY A 1 146 ? 17.67732 40.14116  57.98046  1.000 143.15851 ? 146 GLY H N   1 
ATOM   1119 C CA  . GLY A 1 146 ? 16.74400 40.96327  58.72280  1.000 139.82543 ? 146 GLY H CA  1 
ATOM   1120 C C   . GLY A 1 146 ? 16.03271 40.16252  59.79476  1.000 143.73061 ? 146 GLY H C   1 
ATOM   1121 O O   . GLY A 1 146 ? 15.07987 39.43300  59.50503  1.000 141.75880 ? 146 GLY H O   1 
ATOM   1122 N N   . GLY A 1 147 ? 16.48846 40.28202  61.03899  1.000 122.04631 ? 147 GLY H N   1 
ATOM   1123 C CA  . GLY A 1 147 ? 15.87621 39.56414  62.13969  1.000 105.41709 ? 147 GLY H CA  1 
ATOM   1124 C C   . GLY A 1 147 ? 16.12757 38.06809  62.15923  1.000 121.74246 ? 147 GLY H C   1 
ATOM   1125 O O   . GLY A 1 147 ? 15.99347 37.43829  63.21169  1.000 127.98073 ? 147 GLY H O   1 
ATOM   1126 N N   . THR A 1 148 ? 16.50165 37.48471  61.02082  1.000 122.89481 ? 148 THR H N   1 
ATOM   1127 C CA  . THR A 1 148 ? 16.61618 36.03922  60.87750  1.000 112.42784 ? 148 THR H CA  1 
ATOM   1128 C C   . THR A 1 148 ? 18.04919 35.64527  60.54787  1.000 101.69036 ? 148 THR H C   1 
ATOM   1129 O O   . THR A 1 148 ? 18.75224 36.36349  59.83128  1.000 96.87505  ? 148 THR H O   1 
ATOM   1130 C CB  . THR A 1 148 ? 15.67832 35.51495  59.78346  1.000 97.31236  ? 148 THR H CB  1 
ATOM   1131 O OG1 . THR A 1 148 ? 15.85304 36.28868  58.59009  1.000 107.33402 ? 148 THR H OG1 1 
ATOM   1132 C CG2 . THR A 1 148 ? 14.22981 35.61267  60.23408  1.000 107.69826 ? 148 THR H CG2 1 
ATOM   1133 N N   . ALA A 1 149 ? 18.47059 34.49261  61.06669  1.000 101.75121 ? 149 ALA H N   1 
ATOM   1134 C CA  . ALA A 1 149 ? 19.79645 33.94861  60.81578  1.000 88.33344  ? 149 ALA H CA  1 
ATOM   1135 C C   . ALA A 1 149 ? 19.67788 32.49699  60.37322  1.000 89.50307  ? 149 ALA H C   1 
ATOM   1136 O O   . ALA A 1 149 ? 18.70309 31.81052  60.69256  1.000 88.08515  ? 149 ALA H O   1 
ATOM   1137 C CB  . ALA A 1 149 ? 20.69132 34.04512  62.05872  1.000 100.58280 ? 149 ALA H CB  1 
ATOM   1138 N N   . ALA A 1 150 ? 20.68271 32.03480  59.63453  1.000 87.05106  ? 150 ALA H N   1 
ATOM   1139 C CA  . ALA A 1 150 ? 20.70747 30.68471  59.08814  1.000 73.10748  ? 150 ALA H CA  1 
ATOM   1140 C C   . ALA A 1 150 ? 21.82475 29.88407  59.74123  1.000 65.36532  ? 150 ALA H C   1 
ATOM   1141 O O   . ALA A 1 150 ? 22.96478 30.35340  59.82402  1.000 79.30729  ? 150 ALA H O   1 
ATOM   1142 C CB  . ALA A 1 150 ? 20.89485 30.71165  57.56951  1.000 81.23114  ? 150 ALA H CB  1 
ATOM   1143 N N   . LEU A 1 151 ? 21.49441 28.67882  60.20009  1.000 66.69531  ? 151 LEU H N   1 
ATOM   1144 C CA  . LEU A 1 151 ? 22.47336 27.79406  60.81293  1.000 77.59496  ? 151 LEU H CA  1 
ATOM   1145 C C   . LEU A 1 151 ? 22.09228 26.35388  60.50781  1.000 68.62734  ? 151 LEU H C   1 
ATOM   1146 O O   . LEU A 1 151 ? 20.94258 26.05131  60.17781  1.000 60.81466  ? 151 LEU H O   1 
ATOM   1147 C CB  . LEU A 1 151 ? 22.57843 28.02891  62.32782  1.000 85.94964  ? 151 LEU H CB  1 
ATOM   1148 C CG  . LEU A 1 151 ? 21.41616 27.65855  63.25689  1.000 75.95831  ? 151 LEU H CG  1 
ATOM   1149 C CD1 . LEU A 1 151 ? 21.54028 26.23329  63.78411  1.000 77.75993  ? 151 LEU H CD1 1 
ATOM   1150 C CD2 . LEU A 1 151 ? 21.32158 28.64913  64.40771  1.000 71.81178  ? 151 LEU H CD2 1 
ATOM   1151 N N   . GLY A 1 152 ? 23.07288 25.46766  60.62191  1.000 65.88757  ? 152 GLY H N   1 
ATOM   1152 C CA  . GLY A 1 152 ? 22.82387 24.06548  60.35647  1.000 77.83113  ? 152 GLY H CA  1 
ATOM   1153 C C   . GLY A 1 152 ? 24.04808 23.23003  60.65240  1.000 74.87133  ? 152 GLY H C   1 
ATOM   1154 O O   . GLY A 1 152 ? 25.03185 23.71014  61.21889  1.000 82.09760  ? 152 GLY H O   1 
ATOM   1155 N N   . CYS A 1 153 ? 23.96714 21.95914  60.26583  1.000 66.74267  ? 153 CYS H N   1 
ATOM   1156 C CA  . CYS A 1 153 ? 25.06859 21.02262  60.42088  1.000 86.21034  ? 153 CYS H CA  1 
ATOM   1157 C C   . CYS A 1 153 ? 25.24356 20.22851  59.13480  1.000 83.77431  ? 153 CYS H C   1 
ATOM   1158 O O   . CYS A 1 153 ? 24.29716 20.04458  58.36432  1.000 71.13731  ? 153 CYS H O   1 
ATOM   1159 C CB  . CYS A 1 153 ? 24.84709 20.07158  61.61005  1.000 97.55769  ? 153 CYS H CB  1 
ATOM   1160 S SG  . CYS A 1 153 ? 23.22355 19.27808  61.67334  1.000 116.56014 ? 153 CYS H SG  1 
ATOM   1161 N N   . LEU A 1 154 ? 26.46991 19.76360  58.90927  1.000 86.69528  ? 154 LEU H N   1 
ATOM   1162 C CA  . LEU A 1 154 ? 26.84674 19.06730  57.68376  1.000 72.52405  ? 154 LEU H CA  1 
ATOM   1163 C C   . LEU A 1 154 ? 27.04285 17.58831  57.99334  1.000 86.07174  ? 154 LEU H C   1 
ATOM   1164 O O   . LEU A 1 154 ? 27.95606 17.21960  58.73954  1.000 94.14814  ? 154 LEU H O   1 
ATOM   1165 C CB  . LEU A 1 154 ? 28.11534 19.67348  57.08697  1.000 63.65581  ? 154 LEU H CB  1 
ATOM   1166 C CG  . LEU A 1 154 ? 28.77602 18.89886  55.94470  1.000 68.39892  ? 154 LEU H CG  1 
ATOM   1167 C CD1 . LEU A 1 154 ? 27.87814 18.86761  54.71902  1.000 83.65091  ? 154 LEU H CD1 1 
ATOM   1168 C CD2 . LEU A 1 154 ? 30.13167 19.49866  55.60535  1.000 75.50164  ? 154 LEU H CD2 1 
ATOM   1169 N N   . VAL A 1 155 ? 26.18965 16.74735  57.41754  1.000 84.11591  ? 155 VAL H N   1 
ATOM   1170 C CA  . VAL A 1 155 ? 26.33539 15.29914  57.50744  1.000 76.21436  ? 155 VAL H CA  1 
ATOM   1171 C C   . VAL A 1 155 ? 27.24622 14.86909  56.36373  1.000 82.66556  ? 155 VAL H C   1 
ATOM   1172 O O   . VAL A 1 155 ? 26.87424 14.97036  55.19223  1.000 90.20799  ? 155 VAL H O   1 
ATOM   1173 C CB  . VAL A 1 155 ? 24.97737 14.59116  57.44072  1.000 82.95214  ? 155 VAL H CB  1 
ATOM   1174 C CG1 . VAL A 1 155 ? 25.15318 13.08905  57.58115  1.000 97.36670  ? 155 VAL H CG1 1 
ATOM   1175 C CG2 . VAL A 1 155 ? 24.04759 15.12659  58.51954  1.000 77.68316  ? 155 VAL H CG2 1 
ATOM   1176 N N   . LYS A 1 156 ? 28.44133 14.38840  56.69970  1.000 77.25615  ? 156 LYS H N   1 
ATOM   1177 C CA  . LYS A 1 156 ? 29.48079 14.14063  55.71149  1.000 85.25829  ? 156 LYS H CA  1 
ATOM   1178 C C   . LYS A 1 156 ? 30.00643 12.71723  55.82067  1.000 81.56782  ? 156 LYS H C   1 
ATOM   1179 O O   . LYS A 1 156 ? 30.13055 12.17239  56.92187  1.000 92.32287  ? 156 LYS H O   1 
ATOM   1180 C CB  . LYS A 1 156 ? 30.64066 15.13230  55.87758  1.000 76.30754  ? 156 LYS H CB  1 
ATOM   1181 C CG  . LYS A 1 156 ? 31.40530 15.41766  54.59661  1.000 91.16158  ? 156 LYS H CG  1 
ATOM   1182 C CD  . LYS A 1 156 ? 32.82702 15.86774  54.89206  1.000 86.55300  ? 156 LYS H CD  1 
ATOM   1183 C CE  . LYS A 1 156 ? 33.73773 15.63681  53.69697  1.000 108.04720 ? 156 LYS H CE  1 
ATOM   1184 N NZ  . LYS A 1 156 ? 33.19120 16.24791  52.45297  1.000 109.97254 ? 156 LYS H NZ  1 
ATOM   1185 N N   . ASP A 1 157 ? 30.31341 12.12633  54.66371  1.000 79.42808  ? 157 ASP H N   1 
ATOM   1186 C CA  . ASP A 1 157 ? 31.01640 10.84654  54.56756  1.000 79.59085  ? 157 ASP H CA  1 
ATOM   1187 C C   . ASP A 1 157 ? 30.25492 9.72904   55.28497  1.000 90.94216  ? 157 ASP H C   1 
ATOM   1188 O O   . ASP A 1 157 ? 30.71701 9.15575   56.27366  1.000 103.81364 ? 157 ASP H O   1 
ATOM   1189 C CB  . ASP A 1 157 ? 32.44602 10.97584  55.10441  1.000 86.89192  ? 157 ASP H CB  1 
ATOM   1190 C CG  . ASP A 1 157 ? 33.30601 11.89011  54.25372  1.000 103.06039 ? 157 ASP H CG  1 
ATOM   1191 O OD1 . ASP A 1 157 ? 32.93306 12.14499  53.08877  1.000 91.12167  ? 157 ASP H OD1 1 
ATOM   1192 O OD2 . ASP A 1 157 ? 34.35247 12.35723  54.75063  1.000 116.11901 ? 157 ASP H OD2 1 
ATOM   1193 N N   . TYR A 1 158 ? 29.06799 9.42575   54.76363  1.000 83.92540  ? 158 TYR H N   1 
ATOM   1194 C CA  . TYR A 1 158 ? 28.24536 8.34517   55.28518  1.000 84.15358  ? 158 TYR H CA  1 
ATOM   1195 C C   . TYR A 1 158 ? 27.75321 7.47692   54.13638  1.000 88.67969  ? 158 TYR H C   1 
ATOM   1196 O O   . TYR A 1 158 ? 27.60101 7.94296   53.00389  1.000 89.91625  ? 158 TYR H O   1 
ATOM   1197 C CB  . TYR A 1 158 ? 27.05135 8.87845   56.09240  1.000 89.26197  ? 158 TYR H CB  1 
ATOM   1198 C CG  . TYR A 1 158 ? 25.91920 9.42317   55.25126  1.000 83.38912  ? 158 TYR H CG  1 
ATOM   1199 C CD1 . TYR A 1 158 ? 25.92237 10.74162  54.81727  1.000 86.28797  ? 158 TYR H CD1 1 
ATOM   1200 C CD2 . TYR A 1 158 ? 24.83615 8.62309   54.90845  1.000 86.77883  ? 158 TYR H CD2 1 
ATOM   1201 C CE1 . TYR A 1 158 ? 24.88636 11.24291  54.05192  1.000 89.46428  ? 158 TYR H CE1 1 
ATOM   1202 C CE2 . TYR A 1 158 ? 23.79853 9.11415   54.14469  1.000 92.84063  ? 158 TYR H CE2 1 
ATOM   1203 C CZ  . TYR A 1 158 ? 23.82711 10.42397  53.72022  1.000 87.75474  ? 158 TYR H CZ  1 
ATOM   1204 O OH  . TYR A 1 158 ? 22.79171 10.91260  52.95928  1.000 75.80447  ? 158 TYR H OH  1 
ATOM   1205 N N   . PHE A 1 159 ? 27.50003 6.20637   54.44573  1.000 96.62631  ? 159 PHE H N   1 
ATOM   1206 C CA  . PHE A 1 159 ? 27.05322 5.22477   53.46586  1.000 96.70382  ? 159 PHE H CA  1 
ATOM   1207 C C   . PHE A 1 159 ? 26.55066 3.99309   54.21049  1.000 98.65232  ? 159 PHE H C   1 
ATOM   1208 O O   . PHE A 1 159 ? 27.15799 3.58931   55.21011  1.000 84.83195  ? 159 PHE H O   1 
ATOM   1209 C CB  . PHE A 1 159 ? 28.19591 4.86183   52.51154  1.000 98.03846  ? 159 PHE H CB  1 
ATOM   1210 C CG  . PHE A 1 159 ? 27.88507 3.71873   51.58251  1.000 105.19778 ? 159 PHE H CG  1 
ATOM   1211 C CD1 . PHE A 1 159 ? 27.12658 3.92184   50.44080  1.000 109.18763 ? 159 PHE H CD1 1 
ATOM   1212 C CD2 . PHE A 1 159 ? 28.35653 2.44310   51.84760  1.000 111.40901 ? 159 PHE H CD2 1 
ATOM   1213 C CE1 . PHE A 1 159 ? 26.84103 2.87408   49.58412  1.000 108.01413 ? 159 PHE H CE1 1 
ATOM   1214 C CE2 . PHE A 1 159 ? 28.07404 1.39183   50.99532  1.000 104.77004 ? 159 PHE H CE2 1 
ATOM   1215 C CZ  . PHE A 1 159 ? 27.31560 1.60781   49.86242  1.000 110.32308 ? 159 PHE H CZ  1 
ATOM   1216 N N   . PRO A 1 160 ? 25.44482 3.37348   53.77605  1.000 112.91548 ? 160 PRO H N   1 
ATOM   1217 C CA  . PRO A 1 160 ? 24.54834 3.78332   52.68348  1.000 100.81186 ? 160 PRO H CA  1 
ATOM   1218 C C   . PRO A 1 160 ? 23.55640 4.85860   53.10727  1.000 106.37041 ? 160 PRO H C   1 
ATOM   1219 O O   . PRO A 1 160 ? 23.72937 5.52790   54.12312  1.000 107.33731 ? 160 PRO H O   1 
ATOM   1220 C CB  . PRO A 1 160 ? 23.82045 2.47434   52.31914  1.000 90.42291  ? 160 PRO H CB  1 
ATOM   1221 C CG  . PRO A 1 160 ? 24.67536 1.37405   52.88842  1.000 112.29392 ? 160 PRO H CG  1 
ATOM   1222 C CD  . PRO A 1 160 ? 25.20433 1.97287   54.15424  1.000 117.12075 ? 160 PRO H CD  1 
ATOM   1223 N N   . GLU A 1 161 ? 22.49388 5.03198   52.31963  1.000 91.56752  ? 161 GLU H N   1 
ATOM   1224 C CA  . GLU A 1 161 ? 21.33971 5.90039   52.47879  1.000 87.62531  ? 161 GLU H CA  1 
ATOM   1225 C C   . GLU A 1 161 ? 20.20993 5.14152   53.17134  1.000 97.06522  ? 161 GLU H C   1 
ATOM   1226 O O   . GLU A 1 161 ? 20.14414 3.91058   53.09292  1.000 111.79795 ? 161 GLU H O   1 
ATOM   1227 C CB  . GLU A 1 161 ? 20.86731 6.40221   51.11470  1.000 103.98541 ? 161 GLU H CB  1 
ATOM   1228 C CG  . GLU A 1 161 ? 21.66492 7.58299   50.56933  1.000 97.81975  ? 161 GLU H CG  1 
ATOM   1229 C CD  . GLU A 1 161 ? 21.00014 8.92379   50.82008  1.000 99.69648  ? 161 GLU H CD  1 
ATOM   1230 O OE1 . GLU A 1 161 ? 19.97803 8.96545   51.53429  1.000 113.16900 ? 161 GLU H OE1 1 
ATOM   1231 O OE2 . GLU A 1 161 ? 21.50439 9.94165   50.30059  1.000 88.56970  ? 161 GLU H OE2 1 
ATOM   1232 N N   . PRO A 1 162 ? 19.29425 5.83290   53.86461  1.000 88.25654  ? 162 PRO H N   1 
ATOM   1233 C CA  . PRO A 1 162 ? 19.21124 7.27660   54.08906  1.000 94.02612  ? 162 PRO H CA  1 
ATOM   1234 C C   . PRO A 1 162 ? 19.70020 7.68944   55.47030  1.000 92.81357  ? 162 PRO H C   1 
ATOM   1235 O O   . PRO A 1 162 ? 20.19555 6.87299   56.24270  1.000 96.42856  ? 162 PRO H O   1 
ATOM   1236 C CB  . PRO A 1 162 ? 17.70761 7.55591   53.92441  1.000 103.87097 ? 162 PRO H CB  1 
ATOM   1237 C CG  . PRO A 1 162 ? 17.00108 6.19922   54.12595  1.000 101.72982 ? 162 PRO H CG  1 
ATOM   1238 C CD  . PRO A 1 162 ? 18.08027 5.16678   54.35562  1.000 91.44000  ? 162 PRO H CD  1 
ATOM   1239 N N   . VAL A 1 163 ? 19.56854 8.97243   55.79586  1.000 87.86057  ? 163 VAL H N   1 
ATOM   1240 C CA  . VAL A 1 163 ? 19.83795 9.48178   57.13211  1.000 83.15411  ? 163 VAL H CA  1 
ATOM   1241 C C   . VAL A 1 163 ? 18.70023 10.41697  57.51690  1.000 83.65954  ? 163 VAL H C   1 
ATOM   1242 O O   . VAL A 1 163 ? 18.05702 11.03061  56.65894  1.000 82.41076  ? 163 VAL H O   1 
ATOM   1243 C CB  . VAL A 1 163 ? 21.20890 10.19558  57.21914  1.000 76.69061  ? 163 VAL H CB  1 
ATOM   1244 C CG1 . VAL A 1 163 ? 21.09439 11.65857  56.81495  1.000 73.64417  ? 163 VAL H CG1 1 
ATOM   1245 C CG2 . VAL A 1 163 ? 21.79018 10.06419  58.61771  1.000 101.20355 ? 163 VAL H CG2 1 
ATOM   1246 N N   . THR A 1 164 ? 18.43527 10.50439  58.81715  1.000 84.12218  ? 164 THR H N   1 
ATOM   1247 C CA  . THR A 1 164 ? 17.35627 11.32706  59.34674  1.000 87.71557  ? 164 THR H CA  1 
ATOM   1248 C C   . THR A 1 164 ? 17.94465 12.43247  60.20973  1.000 87.27131  ? 164 THR H C   1 
ATOM   1249 O O   . THR A 1 164 ? 18.75201 12.16305  61.10529  1.000 88.36223  ? 164 THR H O   1 
ATOM   1250 C CB  . THR A 1 164 ? 16.36610 10.48825  60.16060  1.000 91.09859  ? 164 THR H CB  1 
ATOM   1251 O OG1 . THR A 1 164 ? 17.05417 9.84560   61.24073  1.000 102.86151 ? 164 THR H OG1 1 
ATOM   1252 C CG2 . THR A 1 164 ? 15.71499 9.43178   59.28069  1.000 81.34629  ? 164 THR H CG2 1 
ATOM   1253 N N   . VAL A 1 165 ? 17.53950 13.67084  59.93968  1.000 84.12991  ? 165 VAL H N   1 
ATOM   1254 C CA  . VAL A 1 165 ? 18.02573 14.84036  60.66089  1.000 79.95249  ? 165 VAL H CA  1 
ATOM   1255 C C   . VAL A 1 165 ? 16.83871 15.53823  61.30851  1.000 81.08592  ? 165 VAL H C   1 
ATOM   1256 O O   . VAL A 1 165 ? 15.85226 15.85457  60.63312  1.000 80.51469  ? 165 VAL H O   1 
ATOM   1257 C CB  . VAL A 1 165 ? 18.78807 15.80699  59.73582  1.000 81.58237  ? 165 VAL H CB  1 
ATOM   1258 C CG1 . VAL A 1 165 ? 19.53998 16.84235  60.55805  1.000 68.06250  ? 165 VAL H CG1 1 
ATOM   1259 C CG2 . VAL A 1 165 ? 19.74431 15.03982  58.83488  1.000 86.52936  ? 165 VAL H CG2 1 
ATOM   1260 N N   . SER A 1 166 ? 16.93818 15.77587  62.61393  1.000 94.14623  ? 166 SER H N   1 
ATOM   1261 C CA  . SER A 1 166 ? 15.92833 16.50077  63.36841  1.000 92.47177  ? 166 SER H CA  1 
ATOM   1262 C C   . SER A 1 166 ? 16.61195 17.57145  64.20637  1.000 87.93482  ? 166 SER H C   1 
ATOM   1263 O O   . SER A 1 166 ? 17.82299 17.52892  64.43641  1.000 92.14804  ? 166 SER H O   1 
ATOM   1264 C CB  . SER A 1 166 ? 15.10889 15.56457  64.26802  1.000 95.45889  ? 166 SER H CB  1 
ATOM   1265 O OG  . SER A 1 166 ? 15.95397 14.71618  65.02568  1.000 99.27925  ? 166 SER H OG  1 
ATOM   1266 N N   . TRP A 1 167 ? 15.82324 18.54162  64.65933  1.000 82.26549  ? 167 TRP H N   1 
ATOM   1267 C CA  . TRP A 1 167 ? 16.33585 19.67215  65.42028  1.000 84.32501  ? 167 TRP H CA  1 
ATOM   1268 C C   . TRP A 1 167 ? 15.64994 19.73434  66.77609  1.000 95.78881  ? 167 TRP H C   1 
ATOM   1269 O O   . TRP A 1 167 ? 14.41644 19.73858  66.85215  1.000 102.98965 ? 167 TRP H O   1 
ATOM   1270 C CB  . TRP A 1 167 ? 16.13124 20.98338  64.65834  1.000 84.23832  ? 167 TRP H CB  1 
ATOM   1271 C CG  . TRP A 1 167 ? 17.08584 21.15115  63.52054  1.000 86.08609  ? 167 TRP H CG  1 
ATOM   1272 C CD1 . TRP A 1 167 ? 16.90722 20.73863  62.23234  1.000 92.15276  ? 167 TRP H CD1 1 
ATOM   1273 C CD2 . TRP A 1 167 ? 18.37992 21.76172  63.57085  1.000 80.34118  ? 167 TRP H CD2 1 
ATOM   1274 N NE1 . TRP A 1 167 ? 18.00672 21.06295  61.47510  1.000 89.00813  ? 167 TRP H NE1 1 
ATOM   1275 C CE2 . TRP A 1 167 ? 18.92549 21.69128  62.27424  1.000 85.17132  ? 167 TRP H CE2 1 
ATOM   1276 C CE3 . TRP A 1 167 ? 19.12852 22.36500  64.58572  1.000 93.90296  ? 167 TRP H CE3 1 
ATOM   1277 C CZ2 . TRP A 1 167 ? 20.18440 22.20114  61.96630  1.000 81.08286  ? 167 TRP H CZ2 1 
ATOM   1278 C CZ3 . TRP A 1 167 ? 20.37771 22.87028  64.27784  1.000 84.74077  ? 167 TRP H CZ3 1 
ATOM   1279 C CH2 . TRP A 1 167 ? 20.89294 22.78522  62.97991  1.000 72.30476  ? 167 TRP H CH2 1 
ATOM   1280 N N   . ASN A 1 168 ? 16.45747 19.78822  67.83834  1.000 98.43025  ? 168 ASN H N   1 
ATOM   1281 C CA  . ASN A 1 168 ? 15.96631 19.89775  69.21339  1.000 92.68197  ? 168 ASN H CA  1 
ATOM   1282 C C   . ASN A 1 168 ? 14.98373 18.77795  69.54978  1.000 88.19948  ? 168 ASN H C   1 
ATOM   1283 O O   . ASN A 1 168 ? 13.96621 18.99964  70.20969  1.000 87.42678  ? 168 ASN H O   1 
ATOM   1284 C CB  . ASN A 1 168 ? 15.33695 21.26953  69.46516  1.000 79.04435  ? 168 ASN H CB  1 
ATOM   1285 C CG  . ASN A 1 168 ? 16.33668 22.40057  69.33062  1.000 82.26429  ? 168 ASN H CG  1 
ATOM   1286 O OD1 . ASN A 1 168 ? 17.43609 22.34134  69.88105  1.000 93.98147  ? 168 ASN H OD1 1 
ATOM   1287 N ND2 . ASN A 1 168 ? 15.95925 23.43959  68.59590  1.000 90.17715  ? 168 ASN H ND2 1 
ATOM   1288 N N   . SER A 1 169 ? 15.29849 17.56328  69.09317  1.000 84.79158  ? 169 SER H N   1 
ATOM   1289 C CA  . SER A 1 169 ? 14.46833 16.38057  69.33350  1.000 94.20075  ? 169 SER H CA  1 
ATOM   1290 C C   . SER A 1 169 ? 13.03395 16.59609  68.85346  1.000 90.63214  ? 169 SER H C   1 
ATOM   1291 O O   . SER A 1 169 ? 12.07156 16.19461  69.51069  1.000 106.17401 ? 169 SER H O   1 
ATOM   1292 C CB  . SER A 1 169 ? 14.49376 15.97821  70.81038  1.000 95.20598  ? 169 SER H CB  1 
ATOM   1293 O OG  . SER A 1 169 ? 15.78262 15.53215  71.19558  1.000 87.21362  ? 169 SER H OG  1 
ATOM   1294 N N   . GLY A 1 170 ? 12.88972 17.23512  67.69462  1.000 86.59415  ? 170 GLY H N   1 
ATOM   1295 C CA  . GLY A 1 170 ? 11.58921 17.48967  67.11474  1.000 84.68634  ? 170 GLY H CA  1 
ATOM   1296 C C   . GLY A 1 170 ? 10.91122 18.76255  67.57119  1.000 81.73396  ? 170 GLY H C   1 
ATOM   1297 O O   . GLY A 1 170 ? 9.82115  19.07390  67.07420  1.000 91.32426  ? 170 GLY H O   1 
ATOM   1298 N N   . ALA A 1 171 ? 11.51243 19.50639  68.50255  1.000 92.20861  ? 171 ALA H N   1 
ATOM   1299 C CA  . ALA A 1 171 ? 10.90853 20.75697  68.95158  1.000 92.15820  ? 171 ALA H CA  1 
ATOM   1300 C C   . ALA A 1 171 ? 10.89148 21.79677  67.83809  1.000 104.82872 ? 171 ALA H C   1 
ATOM   1301 O O   . ALA A 1 171 ? 9.91774  22.54550  67.69499  1.000 110.25322 ? 171 ALA H O   1 
ATOM   1302 C CB  . ALA A 1 171 ? 11.65286 21.29202  70.17421  1.000 80.49118  ? 171 ALA H CB  1 
ATOM   1303 N N   . LEU A 1 172 ? 11.95695 21.85975  67.04303  1.000 108.23332 ? 172 LEU H N   1 
ATOM   1304 C CA  . LEU A 1 172 ? 12.08544 22.83669  65.96390  1.000 91.30721  ? 172 LEU H CA  1 
ATOM   1305 C C   . LEU A 1 172 ? 11.67035 22.16906  64.65726  1.000 90.62231  ? 172 LEU H C   1 
ATOM   1306 O O   . LEU A 1 172 ? 12.42308 21.37739  64.08426  1.000 99.51887  ? 172 LEU H O   1 
ATOM   1307 C CB  . LEU A 1 172 ? 13.51129 23.37257  65.88981  1.000 87.84711  ? 172 LEU H CB  1 
ATOM   1308 C CG  . LEU A 1 172 ? 13.72725 24.63776  65.05808  1.000 91.93104  ? 172 LEU H CG  1 
ATOM   1309 C CD1 . LEU A 1 172 ? 12.74821 25.72589  65.46935  1.000 85.19927  ? 172 LEU H CD1 1 
ATOM   1310 C CD2 . LEU A 1 172 ? 15.16194 25.12447  65.18979  1.000 94.68606  ? 172 LEU H CD2 1 
ATOM   1311 N N   . THR A 1 173 ? 10.46716 22.49047  64.18827  1.000 92.08542  ? 173 THR H N   1 
ATOM   1312 C CA  . THR A 1 173 ? 9.96378  21.98456  62.91907  1.000 87.95194  ? 173 THR H CA  1 
ATOM   1313 C C   . THR A 1 173 ? 9.74235  23.06774  61.87657  1.000 77.30446  ? 173 THR H C   1 
ATOM   1314 O O   . THR A 1 173 ? 9.82122  22.77592  60.68144  1.000 106.04603 ? 173 THR H O   1 
ATOM   1315 C CB  . THR A 1 173 ? 8.64343  21.22446  63.12421  1.000 99.32358  ? 173 THR H CB  1 
ATOM   1316 O OG1 . THR A 1 173 ? 7.69428  22.07702  63.77652  1.000 113.48060 ? 173 THR H OG1 1 
ATOM   1317 C CG2 . THR A 1 173 ? 8.86970  19.98095  63.97099  1.000 93.41365  ? 173 THR H CG2 1 
ATOM   1318 N N   . SER A 1 174 ? 9.46825  24.30137  62.29086  1.000 81.29080  ? 174 SER H N   1 
ATOM   1319 C CA  . SER A 1 174 ? 9.29174  25.39697  61.35027  1.000 89.74845  ? 174 SER H CA  1 
ATOM   1320 C C   . SER A 1 174 ? 10.64425 25.90272  60.86736  1.000 92.25431  ? 174 SER H C   1 
ATOM   1321 O O   . SER A 1 174 ? 11.59290 26.02647  61.64727  1.000 91.80225  ? 174 SER H O   1 
ATOM   1322 C CB  . SER A 1 174 ? 8.50647  26.53759  61.99810  1.000 91.83598  ? 174 SER H CB  1 
ATOM   1323 O OG  . SER A 1 174 ? 8.64657  27.73763  61.25772  1.000 96.30139  ? 174 SER H OG  1 
ATOM   1324 N N   . GLY A 1 175 ? 10.72749 26.19506  59.57158  1.000 90.47693  ? 175 GLY H N   1 
ATOM   1325 C CA  . GLY A 1 175 ? 11.96417 26.69223  59.00436  1.000 75.81742  ? 175 GLY H CA  1 
ATOM   1326 C C   . GLY A 1 175 ? 13.04400 25.65259  58.81997  1.000 77.16419  ? 175 GLY H C   1 
ATOM   1327 O O   . GLY A 1 175 ? 14.21868 26.00950  58.70645  1.000 71.42073  ? 175 GLY H O   1 
ATOM   1328 N N   . VAL A 1 176 ? 12.68290 24.37249  58.78584  1.000 84.74242  ? 176 VAL H N   1 
ATOM   1329 C CA  . VAL A 1 176 ? 13.63840 23.28428  58.61503  1.000 76.99509  ? 176 VAL H CA  1 
ATOM   1330 C C   . VAL A 1 176 ? 13.58492 22.81234  57.16997  1.000 97.17111  ? 176 VAL H C   1 
ATOM   1331 O O   . VAL A 1 176 ? 12.50407 22.51866  56.64310  1.000 98.59832  ? 176 VAL H O   1 
ATOM   1332 C CB  . VAL A 1 176 ? 13.34301 22.12415  59.58061  1.000 82.93896  ? 176 VAL H CB  1 
ATOM   1333 C CG1 . VAL A 1 176 ? 14.46857 21.10085  59.53845  1.000 68.93489  ? 176 VAL H CG1 1 
ATOM   1334 C CG2 . VAL A 1 176 ? 13.13461 22.64565  60.99345  1.000 93.43293  ? 176 VAL H CG2 1 
ATOM   1335 N N   . HIS A 1 177 ? 14.74919 22.73939  56.52799  1.000 96.13425  ? 177 HIS H N   1 
ATOM   1336 C CA  . HIS A 1 177 ? 14.85571 22.25416  55.15454  1.000 93.44600  ? 177 HIS H CA  1 
ATOM   1337 C C   . HIS A 1 177 ? 16.12257 21.41903  55.04083  1.000 87.38155  ? 177 HIS H C   1 
ATOM   1338 O O   . HIS A 1 177 ? 17.23135 21.96009  55.09672  1.000 75.93029  ? 177 HIS H O   1 
ATOM   1339 C CB  . HIS A 1 177 ? 14.87245 23.40903  54.15279  1.000 90.53091  ? 177 HIS H CB  1 
ATOM   1340 C CG  . HIS A 1 177 ? 14.65026 22.97991  52.73562  1.000 98.46015  ? 177 HIS H CG  1 
ATOM   1341 N ND1 . HIS A 1 177 ? 15.68684 22.74122  51.85906  1.000 90.14265  ? 177 HIS H ND1 1 
ATOM   1342 C CD2 . HIS A 1 177 ? 13.51072 22.74093  52.04422  1.000 95.19442  ? 177 HIS H CD2 1 
ATOM   1343 C CE1 . HIS A 1 177 ? 15.19573 22.37658  50.68819  1.000 87.81914  ? 177 HIS H CE1 1 
ATOM   1344 N NE2 . HIS A 1 177 ? 13.87768 22.36836  50.77382  1.000 111.08626 ? 177 HIS H NE2 1 
ATOM   1345 N N   . THR A 1 178 ? 15.95922 20.10860  54.88379  1.000 86.16794  ? 178 THR H N   1 
ATOM   1346 C CA  . THR A 1 178 ? 17.07656 19.19292  54.69907  1.000 82.68414  ? 178 THR H CA  1 
ATOM   1347 C C   . THR A 1 178 ? 17.26143 18.92481  53.21131  1.000 79.26706  ? 178 THR H C   1 
ATOM   1348 O O   . THR A 1 178 ? 16.30580 18.56297  52.51685  1.000 85.03841  ? 178 THR H O   1 
ATOM   1349 C CB  . THR A 1 178 ? 16.84350 17.88152  55.45175  1.000 80.22933  ? 178 THR H CB  1 
ATOM   1350 O OG1 . THR A 1 178 ? 16.54787 18.16357  56.82546  1.000 79.70271  ? 178 THR H OG1 1 
ATOM   1351 C CG2 . THR A 1 178 ? 18.07927 16.99691  55.37792  1.000 76.43898  ? 178 THR H CG2 1 
ATOM   1352 N N   . PHE A 1 179 ? 18.49093 19.10675  52.72688  1.000 66.25619  ? 179 PHE H N   1 
ATOM   1353 C CA  . PHE A 1 179 ? 18.78799 18.98661  51.30860  1.000 68.97518  ? 179 PHE H CA  1 
ATOM   1354 C C   . PHE A 1 179 ? 19.15593 17.55054  50.94586  1.000 77.09780  ? 179 PHE H C   1 
ATOM   1355 O O   . PHE A 1 179 ? 19.64560 16.79457  51.79161  1.000 77.82238  ? 179 PHE H O   1 
ATOM   1356 C CB  . PHE A 1 179 ? 19.93638 19.91712  50.92851  1.000 75.26867  ? 179 PHE H CB  1 
ATOM   1357 C CG  . PHE A 1 179 ? 19.56727 21.37215  50.94366  1.000 61.34152  ? 179 PHE H CG  1 
ATOM   1358 C CD1 . PHE A 1 179 ? 19.54855 22.08324  52.13205  1.000 71.34819  ? 179 PHE H CD1 1 
ATOM   1359 C CD2 . PHE A 1 179 ? 19.23740 22.02880  49.77061  1.000 70.31390  ? 179 PHE H CD2 1 
ATOM   1360 C CE1 . PHE A 1 179 ? 19.20948 23.42238  52.14998  1.000 69.84941  ? 179 PHE H CE1 1 
ATOM   1361 C CE2 . PHE A 1 179 ? 18.89700 23.36815  49.78178  1.000 76.37478  ? 179 PHE H CE2 1 
ATOM   1362 C CZ  . PHE A 1 179 ? 18.88318 24.06555  50.97295  1.000 72.00221  ? 179 PHE H CZ  1 
ATOM   1363 N N   . PRO A 1 180 ? 18.92192 17.15235  49.69619  1.000 74.58922  ? 180 PRO H N   1 
ATOM   1364 C CA  . PRO A 1 180 ? 19.36832 15.82888  49.24970  1.000 66.32371  ? 180 PRO H CA  1 
ATOM   1365 C C   . PRO A 1 180 ? 20.88557 15.73514  49.21791  1.000 71.91108  ? 180 PRO H C   1 
ATOM   1366 O O   . PRO A 1 180 ? 21.59294 16.73370  49.06285  1.000 69.41074  ? 180 PRO H O   1 
ATOM   1367 C CB  . PRO A 1 180 ? 18.77145 15.71016  47.84220  1.000 82.18209  ? 180 PRO H CB  1 
ATOM   1368 C CG  . PRO A 1 180 ? 18.57458 17.12961  47.40493  1.000 91.80622  ? 180 PRO H CG  1 
ATOM   1369 C CD  . PRO A 1 180 ? 18.15354 17.84828  48.65079  1.000 74.10203  ? 180 PRO H CD  1 
ATOM   1370 N N   . ALA A 1 181 ? 21.38147 14.51083  49.37139  1.000 63.36544  ? 181 ALA H N   1 
ATOM   1371 C CA  . ALA A 1 181 ? 22.81166 14.27878  49.48747  1.000 70.27706  ? 181 ALA H CA  1 
ATOM   1372 C C   . ALA A 1 181 ? 23.48278 14.23333  48.11616  1.000 69.56384  ? 181 ALA H C   1 
ATOM   1373 O O   . ALA A 1 181 ? 22.83612 14.07294  47.07723  1.000 50.45524  ? 181 ALA H O   1 
ATOM   1374 C CB  . ALA A 1 181 ? 23.08301 12.97759  50.24298  1.000 77.16611  ? 181 ALA H CB  1 
ATOM   1375 N N   . VAL A 1 182 ? 24.80670 14.37992  48.13129  1.000 61.46625  ? 182 VAL H N   1 
ATOM   1376 C CA  . VAL A 1 182 ? 25.64421 14.25834  46.94386  1.000 67.59136  ? 182 VAL H CA  1 
ATOM   1377 C C   . VAL A 1 182 ? 26.44430 12.96926  47.05107  1.000 77.64306  ? 182 VAL H C   1 
ATOM   1378 O O   . VAL A 1 182 ? 26.97492 12.64311  48.11940  1.000 86.92044  ? 182 VAL H O   1 
ATOM   1379 C CB  . VAL A 1 182 ? 26.59078 15.46460  46.77229  1.000 73.07165  ? 182 VAL H CB  1 
ATOM   1380 C CG1 . VAL A 1 182 ? 25.83989 16.67146  46.25207  1.000 70.21686  ? 182 VAL H CG1 1 
ATOM   1381 C CG2 . VAL A 1 182 ? 27.28500 15.79478  48.08421  1.000 63.18600  ? 182 VAL H CG2 1 
ATOM   1382 N N   . LEU A 1 183 ? 26.52353 12.23138  45.94712  1.000 78.64096  ? 183 LEU H N   1 
ATOM   1383 C CA  . LEU A 1 183 ? 27.36569 11.03963  45.87715  1.000 81.45266  ? 183 LEU H CA  1 
ATOM   1384 C C   . LEU A 1 183 ? 28.73509 11.47521  45.37289  1.000 81.80184  ? 183 LEU H C   1 
ATOM   1385 O O   . LEU A 1 183 ? 28.93399 11.67819  44.17294  1.000 100.65246 ? 183 LEU H O   1 
ATOM   1386 C CB  . LEU A 1 183 ? 26.74144 9.97915   44.97774  1.000 84.77199  ? 183 LEU H CB  1 
ATOM   1387 C CG  . LEU A 1 183 ? 27.44101 8.61768   44.98353  1.000 92.05284  ? 183 LEU H CG  1 
ATOM   1388 C CD1 . LEU A 1 183 ? 27.59197 8.09886   46.40510  1.000 90.36888  ? 183 LEU H CD1 1 
ATOM   1389 C CD2 . LEU A 1 183 ? 26.68381 7.61699   44.12466  1.000 97.79986  ? 183 LEU H CD2 1 
ATOM   1390 N N   . GLN A 1 184 ? 29.68200 11.62437  46.29510  1.000 88.30658  ? 184 GLN H N   1 
ATOM   1391 C CA  . GLN A 1 184 ? 31.01510 12.08128  45.94154  1.000 94.56065  ? 184 GLN H CA  1 
ATOM   1392 C C   . GLN A 1 184 ? 31.76565 10.99434  45.17358  1.000 101.67757 ? 184 GLN H C   1 
ATOM   1393 O O   . GLN A 1 184 ? 31.34769 9.83438   45.10689  1.000 102.63878 ? 184 GLN H O   1 
ATOM   1394 C CB  . GLN A 1 184 ? 31.79146 12.48433  47.19535  1.000 94.71644  ? 184 GLN H CB  1 
ATOM   1395 C CG  . GLN A 1 184 ? 30.99378 13.33585  48.17261  1.000 91.07205  ? 184 GLN H CG  1 
ATOM   1396 C CD  . GLN A 1 184 ? 31.56011 13.29885  49.57997  1.000 94.60147  ? 184 GLN H CD  1 
ATOM   1397 O OE1 . GLN A 1 184 ? 31.89644 14.33465  50.15415  1.000 96.89351  ? 184 GLN H OE1 1 
ATOM   1398 N NE2 . GLN A 1 184 ? 31.66667 12.10122  50.14367  1.000 100.81157 ? 184 GLN H NE2 1 
ATOM   1399 N N   . SER A 1 185 ? 32.89396 11.39105  44.57849  1.000 105.68789 ? 185 SER H N   1 
ATOM   1400 C CA  . SER A 1 185 ? 33.72161 10.44363  43.84034  1.000 102.51762 ? 185 SER H CA  1 
ATOM   1401 C C   . SER A 1 185 ? 34.25060 9.32700   44.73033  1.000 101.87170 ? 185 SER H C   1 
ATOM   1402 O O   . SER A 1 185 ? 34.58873 8.25178   44.22333  1.000 82.76454  ? 185 SER H O   1 
ATOM   1403 C CB  . SER A 1 185 ? 34.88480 11.17537  43.16788  1.000 95.18393  ? 185 SER H CB  1 
ATOM   1404 O OG  . SER A 1 185 ? 35.61321 11.94818  44.10612  1.000 110.69399 ? 185 SER H OG  1 
ATOM   1405 N N   . SER A 1 186 ? 34.32837 9.55638   46.04152  1.000 97.55916  ? 186 SER H N   1 
ATOM   1406 C CA  . SER A 1 186 ? 34.73119 8.52311   46.98538  1.000 82.70605  ? 186 SER H CA  1 
ATOM   1407 C C   . SER A 1 186 ? 33.63687 7.49607   47.24290  1.000 86.35658  ? 186 SER H C   1 
ATOM   1408 O O   . SER A 1 186 ? 33.90311 6.48479   47.90131  1.000 83.10633  ? 186 SER H O   1 
ATOM   1409 C CB  . SER A 1 186 ? 35.15451 9.16006   48.31130  1.000 99.14820  ? 186 SER H CB  1 
ATOM   1410 O OG  . SER A 1 186 ? 34.14175 10.01751  48.80913  1.000 102.99420 ? 186 SER H OG  1 
ATOM   1411 N N   . GLY A 1 187 ? 32.42368 7.72638   46.74608  1.000 96.15977  ? 187 GLY H N   1 
ATOM   1412 C CA  . GLY A 1 187 ? 31.32172 6.81851   46.98276  1.000 85.45782  ? 187 GLY H CA  1 
ATOM   1413 C C   . GLY A 1 187 ? 30.59529 7.01828   48.29170  1.000 94.34693  ? 187 GLY H C   1 
ATOM   1414 O O   . GLY A 1 187 ? 29.81004 6.14764   48.68396  1.000 102.95118 ? 187 GLY H O   1 
ATOM   1415 N N   . LEU A 1 188 ? 30.82790 8.13245   48.97936  1.000 90.41520  ? 188 LEU H N   1 
ATOM   1416 C CA  . LEU A 1 188 ? 30.20591 8.41886   50.26455  1.000 85.77403  ? 188 LEU H CA  1 
ATOM   1417 C C   . LEU A 1 188 ? 29.25715 9.60034   50.11572  1.000 79.12705  ? 188 LEU H C   1 
ATOM   1418 O O   . LEU A 1 188 ? 29.61770 10.61993  49.51842  1.000 86.02663  ? 188 LEU H O   1 
ATOM   1419 C CB  . LEU A 1 188 ? 31.26621 8.71720   51.32693  1.000 88.89600  ? 188 LEU H CB  1 
ATOM   1420 C CG  . LEU A 1 188 ? 32.20170 7.56073   51.68695  1.000 74.53515  ? 188 LEU H CG  1 
ATOM   1421 C CD1 . LEU A 1 188 ? 33.43273 8.07276   52.41694  1.000 79.02910  ? 188 LEU H CD1 1 
ATOM   1422 C CD2 . LEU A 1 188 ? 31.47533 6.51939   52.52261  1.000 77.28538  ? 188 LEU H CD2 1 
ATOM   1423 N N   . TYR A 1 189 ? 28.05073 9.46000   50.65706  1.000 75.61264  ? 189 TYR H N   1 
ATOM   1424 C CA  . TYR A 1 189 ? 27.04741 10.50761  50.56209  1.000 77.79141  ? 189 TYR H CA  1 
ATOM   1425 C C   . TYR A 1 189 ? 27.34655 11.63654  51.54584  1.000 81.61504  ? 189 TYR H C   1 
ATOM   1426 O O   . TYR A 1 189 ? 28.11504 11.48145  52.49907  1.000 93.06320  ? 189 TYR H O   1 
ATOM   1427 C CB  . TYR A 1 189 ? 25.65246 9.94061   50.82567  1.000 84.02686  ? 189 TYR H CB  1 
ATOM   1428 C CG  . TYR A 1 189 ? 25.21382 8.89432   49.82693  1.000 89.47062  ? 189 TYR H CG  1 
ATOM   1429 C CD1 . TYR A 1 189 ? 24.55157 9.25394   48.66124  1.000 84.54062  ? 189 TYR H CD1 1 
ATOM   1430 C CD2 . TYR A 1 189 ? 25.46168 7.54642   50.05036  1.000 96.48711  ? 189 TYR H CD2 1 
ATOM   1431 C CE1 . TYR A 1 189 ? 24.14769 8.30070   47.74595  1.000 96.68139  ? 189 TYR H CE1 1 
ATOM   1432 C CE2 . TYR A 1 189 ? 25.06230 6.58610   49.14077  1.000 105.00731 ? 189 TYR H CE2 1 
ATOM   1433 C CZ  . TYR A 1 189 ? 24.40565 6.96863   47.99046  1.000 102.70445 ? 189 TYR H CZ  1 
ATOM   1434 O OH  . TYR A 1 189 ? 24.00580 6.01566   47.08155  1.000 107.18365 ? 189 TYR H OH  1 
ATOM   1435 N N   . SER A 1 190 ? 26.72119 12.78730  51.30004  1.000 80.37759  ? 190 SER H N   1 
ATOM   1436 C CA  . SER A 1 190 ? 26.89352 13.95762  52.15940  1.000 73.54753  ? 190 SER H CA  1 
ATOM   1437 C C   . SER A 1 190 ? 25.74589 14.92024  51.90256  1.000 74.27551  ? 190 SER H C   1 
ATOM   1438 O O   . SER A 1 190 ? 25.56057 15.36540  50.76584  1.000 89.18020  ? 190 SER H O   1 
ATOM   1439 C CB  . SER A 1 190 ? 28.23697 14.63978  51.89269  1.000 62.26524  ? 190 SER H CB  1 
ATOM   1440 O OG  . SER A 1 190 ? 29.31134 13.88714  52.42668  1.000 91.21131  ? 190 SER H OG  1 
ATOM   1441 N N   . LEU A 1 191 ? 24.98421 15.24809  52.94522  1.000 69.71391  ? 191 LEU H N   1 
ATOM   1442 C CA  . LEU A 1 191 ? 23.88977 16.20315  52.83810  1.000 75.88035  ? 191 LEU H CA  1 
ATOM   1443 C C   . LEU A 1 191 ? 24.02122 17.26067  53.92638  1.000 72.71135  ? 191 LEU H C   1 
ATOM   1444 O O   . LEU A 1 191 ? 24.88198 17.18011  54.80712  1.000 72.25966  ? 191 LEU H O   1 
ATOM   1445 C CB  . LEU A 1 191 ? 22.51777 15.51371  52.92331  1.000 66.53396  ? 191 LEU H CB  1 
ATOM   1446 C CG  . LEU A 1 191 ? 22.20891 14.54719  54.06958  1.000 73.69171  ? 191 LEU H CG  1 
ATOM   1447 C CD1 . LEU A 1 191 ? 21.74115 15.28414  55.31670  1.000 77.49157  ? 191 LEU H CD1 1 
ATOM   1448 C CD2 . LEU A 1 191 ? 21.15786 13.54536  53.62744  1.000 82.20739  ? 191 LEU H CD2 1 
ATOM   1449 N N   . SER A 1 192 ? 23.14557 18.26215  53.85565  1.000 74.05547  ? 192 SER H N   1 
ATOM   1450 C CA  . SER A 1 192 ? 23.14152 19.36496  54.80441  1.000 70.08684  ? 192 SER H CA  1 
ATOM   1451 C C   . SER A 1 192 ? 21.71254 19.67852  55.21928  1.000 69.32317  ? 192 SER H C   1 
ATOM   1452 O O   . SER A 1 192 ? 20.78525 19.57383  54.41182  1.000 65.93789  ? 192 SER H O   1 
ATOM   1453 C CB  . SER A 1 192 ? 23.79644 20.61802  54.20718  1.000 66.41639  ? 192 SER H CB  1 
ATOM   1454 O OG  . SER A 1 192 ? 25.16945 20.69398  54.54996  1.000 84.58090  ? 192 SER H OG  1 
ATOM   1455 N N   . SER A 1 193 ? 21.54440 20.06446  56.48102  1.000 58.87216  ? 193 SER H N   1 
ATOM   1456 C CA  . SER A 1 193 ? 20.26780 20.52077  57.01295  1.000 60.25183  ? 193 SER H CA  1 
ATOM   1457 C C   . SER A 1 193 ? 20.45488 21.92180  57.57459  1.000 57.58929  ? 193 SER H C   1 
ATOM   1458 O O   . SER A 1 193 ? 21.43944 22.18493  58.27227  1.000 61.89859  ? 193 SER H O   1 
ATOM   1459 C CB  . SER A 1 193 ? 19.74503 19.57200  58.09575  1.000 71.54716  ? 193 SER H CB  1 
ATOM   1460 O OG  . SER A 1 193 ? 18.39715 19.86238  58.42412  1.000 76.90618  ? 193 SER H OG  1 
ATOM   1461 N N   . VAL A 1 194 ? 19.51934 22.81789  57.26461  1.000 60.97778  ? 194 VAL H N   1 
ATOM   1462 C CA  . VAL A 1 194 ? 19.61728 24.21607  57.66132  1.000 63.45184  ? 194 VAL H CA  1 
ATOM   1463 C C   . VAL A 1 194 ? 18.29293 24.65763  58.27014  1.000 71.94998  ? 194 VAL H C   1 
ATOM   1464 O O   . VAL A 1 194 ? 17.21685 24.20127  57.86971  1.000 76.94685  ? 194 VAL H O   1 
ATOM   1465 C CB  . VAL A 1 194 ? 20.01573 25.12175  56.46912  1.000 51.12043  ? 194 VAL H CB  1 
ATOM   1466 C CG1 . VAL A 1 194 ? 18.86688 25.26296  55.47722  1.000 75.25078  ? 194 VAL H CG1 1 
ATOM   1467 C CG2 . VAL A 1 194 ? 20.48561 26.48425  56.95765  1.000 53.26251  ? 194 VAL H CG2 1 
ATOM   1468 N N   . VAL A 1 195 ? 18.38090 25.53335  59.27008  1.000 72.72114  ? 195 VAL H N   1 
ATOM   1469 C CA  . VAL A 1 195 ? 17.21281 26.08949  59.94233  1.000 77.54609  ? 195 VAL H CA  1 
ATOM   1470 C C   . VAL A 1 195 ? 17.35944 27.60342  59.99589  1.000 78.88579  ? 195 VAL H C   1 
ATOM   1471 O O   . VAL A 1 195 ? 18.41969 28.11717  60.37048  1.000 69.71593  ? 195 VAL H O   1 
ATOM   1472 C CB  . VAL A 1 195 ? 17.03028 25.51197  61.36016  1.000 74.29737  ? 195 VAL H CB  1 
ATOM   1473 C CG1 . VAL A 1 195 ? 16.41767 24.12528  61.29004  1.000 86.70262  ? 195 VAL H CG1 1 
ATOM   1474 C CG2 . VAL A 1 195 ? 18.35692 25.47012  62.10108  1.000 72.73576  ? 195 VAL H CG2 1 
ATOM   1475 N N   . THR A 1 196 ? 16.30159 28.31393  59.61212  1.000 84.66178  ? 196 THR H N   1 
ATOM   1476 C CA  . THR A 1 196 ? 16.26960 29.77042  59.69033  1.000 71.49262  ? 196 THR H CA  1 
ATOM   1477 C C   . THR A 1 196 ? 15.67237 30.16195  61.03643  1.000 80.57739  ? 196 THR H C   1 
ATOM   1478 O O   . THR A 1 196 ? 14.47925 29.95364  61.27925  1.000 108.34138 ? 196 THR H O   1 
ATOM   1479 C CB  . THR A 1 196 ? 15.46423 30.36231  58.53674  1.000 83.06355  ? 196 THR H CB  1 
ATOM   1480 O OG1 . THR A 1 196 ? 15.65940 29.56966  57.35876  1.000 93.39948  ? 196 THR H OG1 1 
ATOM   1481 C CG2 . THR A 1 196 ? 15.90742 31.79139  58.25815  1.000 95.40274  ? 196 THR H CG2 1 
ATOM   1482 N N   . VAL A 1 197 ? 16.49946 30.72904  61.90855  1.000 86.53187  ? 197 VAL H N   1 
ATOM   1483 C CA  . VAL A 1 197 ? 16.08548 31.06159  63.26922  1.000 82.11372  ? 197 VAL H CA  1 
ATOM   1484 C C   . VAL A 1 197 ? 16.27280 32.55792  63.49328  1.000 85.51427  ? 197 VAL H C   1 
ATOM   1485 O O   . VAL A 1 197 ? 17.09363 33.18606  62.80807  1.000 91.15038  ? 197 VAL H O   1 
ATOM   1486 C CB  . VAL A 1 197 ? 16.87006 30.23710  64.30373  1.000 80.66197  ? 197 VAL H CB  1 
ATOM   1487 C CG1 . VAL A 1 197 ? 16.87199 28.76428  63.92141  1.000 86.96338  ? 197 VAL H CG1 1 
ATOM   1488 C CG2 . VAL A 1 197 ? 18.29326 30.75747  64.43546  1.000 75.50324  ? 197 VAL H CG2 1 
ATOM   1489 N N   . PRO A 1 198 ? 15.52517 33.17442  64.40966  1.000 96.15645  ? 198 PRO H N   1 
ATOM   1490 C CA  . PRO A 1 198 ? 15.73690 34.59991  64.68758  1.000 101.35784 ? 198 PRO H CA  1 
ATOM   1491 C C   . PRO A 1 198 ? 17.13551 34.85792  65.22822  1.000 104.54758 ? 198 PRO H C   1 
ATOM   1492 O O   . PRO A 1 198 ? 17.67078 34.08052  66.02160  1.000 97.07242  ? 198 PRO H O   1 
ATOM   1493 C CB  . PRO A 1 198 ? 14.65882 34.92681  65.72840  1.000 85.25566  ? 198 PRO H CB  1 
ATOM   1494 C CG  . PRO A 1 198 ? 14.25651 33.60901  66.30315  1.000 93.83557  ? 198 PRO H CG  1 
ATOM   1495 C CD  . PRO A 1 198 ? 14.41356 32.61608  65.19719  1.000 103.51253 ? 198 PRO H CD  1 
ATOM   1496 N N   . SER A 1 199 ? 17.72468 35.97273  64.78971  1.000 103.75710 ? 199 SER H N   1 
ATOM   1497 C CA  . SER A 1 199 ? 19.07526 36.31391  65.22231  1.000 111.21255 ? 199 SER H CA  1 
ATOM   1498 C C   . SER A 1 199 ? 19.09714 36.81788  66.65924  1.000 113.75459 ? 199 SER H C   1 
ATOM   1499 O O   . SER A 1 199 ? 20.12779 36.71520  67.33425  1.000 102.19912 ? 199 SER H O   1 
ATOM   1500 C CB  . SER A 1 199 ? 19.67756 37.35852  64.28329  1.000 109.91777 ? 199 SER H CB  1 
ATOM   1501 O OG  . SER A 1 199 ? 19.00103 38.59773  64.40207  1.000 121.85347 ? 199 SER H OG  1 
ATOM   1502 N N   . SER A 1 200 ? 17.98095 37.37120  67.13895  1.000 113.96528 ? 200 SER H N   1 
ATOM   1503 C CA  . SER A 1 200 ? 17.92610 37.85389  68.51511  1.000 94.26134  ? 200 SER H CA  1 
ATOM   1504 C C   . SER A 1 200 ? 18.06655 36.70830  69.50947  1.000 94.89180  ? 200 SER H C   1 
ATOM   1505 O O   . SER A 1 200 ? 18.75908 36.83873  70.52588  1.000 98.91174  ? 200 SER H O   1 
ATOM   1506 C CB  . SER A 1 200 ? 16.62107 38.61177  68.75035  1.000 98.78136  ? 200 SER H CB  1 
ATOM   1507 O OG  . SER A 1 200 ? 16.26977 39.38345  67.61493  1.000 107.85490 ? 200 SER H OG  1 
ATOM   1508 N N   . SER A 1 201 ? 17.41557 35.57640  69.23371  1.000 100.53701 ? 201 SER H N   1 
ATOM   1509 C CA  . SER A 1 201 ? 17.50017 34.41670  70.11253  1.000 89.10234  ? 201 SER H CA  1 
ATOM   1510 C C   . SER A 1 201 ? 18.87794 33.76992  70.10608  1.000 90.90834  ? 201 SER H C   1 
ATOM   1511 O O   . SER A 1 201 ? 19.15736 32.94543  70.98319  1.000 98.80771  ? 201 SER H O   1 
ATOM   1512 C CB  . SER A 1 201 ? 16.44553 33.38126  69.71820  1.000 104.69646 ? 201 SER H CB  1 
ATOM   1513 O OG  . SER A 1 201 ? 16.87227 32.62055  68.60087  1.000 118.70273 ? 201 SER H OG  1 
ATOM   1514 N N   . LEU A 1 202 ? 19.73252 34.11056  69.14360  1.000 96.04125  ? 202 LEU H N   1 
ATOM   1515 C CA  . LEU A 1 202 ? 21.07590 33.55080  69.10294  1.000 97.13620  ? 202 LEU H CA  1 
ATOM   1516 C C   . LEU A 1 202 ? 21.86704 33.99306  70.32728  1.000 101.72629 ? 202 LEU H C   1 
ATOM   1517 O O   . LEU A 1 202 ? 21.87506 35.17450  70.68588  1.000 95.47554  ? 202 LEU H O   1 
ATOM   1518 C CB  . LEU A 1 202 ? 21.78700 33.98421  67.82154  1.000 79.86088  ? 202 LEU H CB  1 
ATOM   1519 C CG  . LEU A 1 202 ? 21.55019 33.10921  66.58951  1.000 84.00170  ? 202 LEU H CG  1 
ATOM   1520 C CD1 . LEU A 1 202 ? 22.46946 33.52772  65.45426  1.000 107.17551 ? 202 LEU H CD1 1 
ATOM   1521 C CD2 . LEU A 1 202 ? 21.73851 31.63629  66.92380  1.000 91.29996  ? 202 LEU H CD2 1 
ATOM   1522 N N   . GLY A 1 203 ? 22.53406 33.03450  70.97062  1.000 105.33987 ? 203 GLY H N   1 
ATOM   1523 C CA  . GLY A 1 203 ? 23.26743 33.26056  72.19109  1.000 106.41025 ? 203 GLY H CA  1 
ATOM   1524 C C   . GLY A 1 203 ? 22.52759 32.82805  73.44214  1.000 101.59719 ? 203 GLY H C   1 
ATOM   1525 O O   . GLY A 1 203 ? 23.16734 32.45690  74.43246  1.000 102.12153 ? 203 GLY H O   1 
ATOM   1526 N N   . THR A 1 204 ? 21.19745 32.86315  73.41709  1.000 99.48611  ? 204 THR H N   1 
ATOM   1527 C CA  . THR A 1 204 ? 20.36832 32.40540  74.52588  1.000 93.06328  ? 204 THR H CA  1 
ATOM   1528 C C   . THR A 1 204 ? 19.68402 31.07736  74.24976  1.000 106.80440 ? 204 THR H C   1 
ATOM   1529 O O   . THR A 1 204 ? 19.59536 30.23481  75.14631  1.000 104.85423 ? 204 THR H O   1 
ATOM   1530 C CB  . THR A 1 204 ? 19.30309 33.45657  74.86097  1.000 94.96919  ? 204 THR H CB  1 
ATOM   1531 O OG1 . THR A 1 204 ? 19.91750 34.74710  74.96333  1.000 104.92187 ? 204 THR H OG1 1 
ATOM   1532 C CG2 . THR A 1 204 ? 18.61895 33.12197  76.17892  1.000 95.68876  ? 204 THR H CG2 1 
ATOM   1533 N N   . GLN A 1 205 ? 19.20218 30.86959  73.02716  1.000 104.87138 ? 205 GLN H N   1 
ATOM   1534 C CA  . GLN A 1 205 ? 18.53912 29.62995  72.64925  1.000 96.62635  ? 205 GLN H CA  1 
ATOM   1535 C C   . GLN A 1 205 ? 19.56657 28.63839  72.11857  1.000 94.40754  ? 205 GLN H C   1 
ATOM   1536 O O   . GLN A 1 205 ? 20.43311 29.00156  71.31646  1.000 98.07155  ? 205 GLN H O   1 
ATOM   1537 C CB  . GLN A 1 205 ? 17.46263 29.89674  71.59619  1.000 77.41573  ? 205 GLN H CB  1 
ATOM   1538 C CG  . GLN A 1 205 ? 16.77791 28.64575  71.07152  1.000 92.17280  ? 205 GLN H CG  1 
ATOM   1539 C CD  . GLN A 1 205 ? 15.84553 28.02207  72.09073  1.000 106.40250 ? 205 GLN H CD  1 
ATOM   1540 O OE1 . GLN A 1 205 ? 16.11088 26.93843  72.61141  1.000 110.38428 ? 205 GLN H OE1 1 
ATOM   1541 N NE2 . GLN A 1 205 ? 14.74470 28.70568  72.38124  1.000 100.08228 ? 205 GLN H NE2 1 
ATOM   1542 N N   . THR A 1 206 ? 19.46723 27.39030  72.56863  1.000 92.86619  ? 206 THR H N   1 
ATOM   1543 C CA  . THR A 1 206 ? 20.37848 26.33768  72.14139  1.000 105.48791 ? 206 THR H CA  1 
ATOM   1544 C C   . THR A 1 206 ? 19.78511 25.59498  70.95124  1.000 99.60172  ? 206 THR H C   1 
ATOM   1545 O O   . THR A 1 206 ? 18.63587 25.14456  71.00174  1.000 99.16994  ? 206 THR H O   1 
ATOM   1546 C CB  . THR A 1 206 ? 20.65632 25.36242  73.28593  1.000 101.00419 ? 206 THR H CB  1 
ATOM   1547 O OG1 . THR A 1 206 ? 19.41679 24.94496  73.87162  1.000 111.51226 ? 206 THR H OG1 1 
ATOM   1548 C CG2 . THR A 1 206 ? 21.51739 26.02428  74.35134  1.000 102.89225 ? 206 THR H CG2 1 
ATOM   1549 N N   . TYR A 1 207 ? 20.57156 25.46848  69.88523  1.000 82.11652  ? 207 TYR H N   1 
ATOM   1550 C CA  . TYR A 1 207 ? 20.14374 24.81035  68.65538  1.000 88.26354  ? 207 TYR H CA  1 
ATOM   1551 C C   . TYR A 1 207 ? 20.98084 23.55084  68.46779  1.000 88.22761  ? 207 TYR H C   1 
ATOM   1552 O O   . TYR A 1 207 ? 22.19333 23.63132  68.24248  1.000 82.57751  ? 207 TYR H O   1 
ATOM   1553 C CB  . TYR A 1 207 ? 20.28189 25.75125  67.46077  1.000 92.93994  ? 207 TYR H CB  1 
ATOM   1554 C CG  . TYR A 1 207 ? 19.32781 26.92390  67.49807  1.000 83.74621  ? 207 TYR H CG  1 
ATOM   1555 C CD1 . TYR A 1 207 ? 17.96395 26.74128  67.31016  1.000 77.32868  ? 207 TYR H CD1 1 
ATOM   1556 C CD2 . TYR A 1 207 ? 19.79112 28.21339  67.72531  1.000 72.76931  ? 207 TYR H CD2 1 
ATOM   1557 C CE1 . TYR A 1 207 ? 17.08859 27.81010  67.34547  1.000 67.09524  ? 207 TYR H CE1 1 
ATOM   1558 C CE2 . TYR A 1 207 ? 18.92393 29.28826  67.76177  1.000 68.93746  ? 207 TYR H CE2 1 
ATOM   1559 C CZ  . TYR A 1 207 ? 17.57415 29.08107  67.57134  1.000 76.48673  ? 207 TYR H CZ  1 
ATOM   1560 O OH  . TYR A 1 207 ? 16.70726 30.14914  67.60685  1.000 79.21278  ? 207 TYR H OH  1 
ATOM   1561 N N   . ILE A 1 208 ? 20.33383 22.39222  68.56092  1.000 82.21284  ? 208 ILE H N   1 
ATOM   1562 C CA  . ILE A 1 208 ? 20.99387 21.09892  68.43524  1.000 86.63085  ? 208 ILE H CA  1 
ATOM   1563 C C   . ILE A 1 208 ? 20.31787 20.32129  67.31621  1.000 94.85915  ? 208 ILE H C   1 
ATOM   1564 O O   . ILE A 1 208 ? 19.08883 20.18482  67.30341  1.000 96.40836  ? 208 ILE H O   1 
ATOM   1565 C CB  . ILE A 1 208 ? 20.94736 20.30615  69.75479  1.000 90.41884  ? 208 ILE H CB  1 
ATOM   1566 C CG1 . ILE A 1 208 ? 21.71076 21.04890  70.85244  1.000 96.01826  ? 208 ILE H CG1 1 
ATOM   1567 C CG2 . ILE A 1 208 ? 21.51340 18.90702  69.56092  1.000 96.08360  ? 208 ILE H CG2 1 
ATOM   1568 C CD1 . ILE A 1 208 ? 20.86440 21.38788  72.05972  1.000 106.57230 ? 208 ILE H CD1 1 
ATOM   1569 N N   . CYS A 1 209 ? 21.11723 19.81478  66.38211  1.000 90.67151  ? 209 CYS H N   1 
ATOM   1570 C CA  . CYS A 1 209 ? 20.62270 18.97015  65.30411  1.000 92.71991  ? 209 CYS H CA  1 
ATOM   1571 C C   . CYS A 1 209 ? 20.93930 17.51410  65.62277  1.000 100.43517 ? 209 CYS H C   1 
ATOM   1572 O O   . CYS A 1 209 ? 22.06147 17.18905  66.02554  1.000 97.06692  ? 209 CYS H O   1 
ATOM   1573 C CB  . CYS A 1 209 ? 21.22509 19.38505  63.95780  1.000 94.95754  ? 209 CYS H CB  1 
ATOM   1574 S SG  . CYS A 1 209 ? 22.93997 18.88639  63.64823  1.000 107.31863 ? 209 CYS H SG  1 
ATOM   1575 N N   . ASN A 1 210 ? 19.94195 16.64807  65.46692  1.000 99.98338  ? 210 ASN H N   1 
ATOM   1576 C CA  . ASN A 1 210 ? 20.05942 15.23350  65.79779  1.000 86.58630  ? 210 ASN H CA  1 
ATOM   1577 C C   . ASN A 1 210 ? 20.12615 14.42896  64.50773  1.000 77.23811  ? 210 ASN H C   1 
ATOM   1578 O O   . ASN A 1 210 ? 19.22106 14.51558  63.67128  1.000 84.28244  ? 210 ASN H O   1 
ATOM   1579 C CB  . ASN A 1 210 ? 18.88352 14.77381  66.66049  1.000 96.90264  ? 210 ASN H CB  1 
ATOM   1580 C CG  . ASN A 1 210 ? 18.31764 15.89008  67.51927  1.000 102.84081 ? 210 ASN H CG  1 
ATOM   1581 O OD1 . ASN A 1 210 ? 17.31129 16.50805  67.17072  1.000 99.93216  ? 210 ASN H OD1 1 
ATOM   1582 N ND2 . ASN A 1 210 ? 18.96369 16.15327  68.64977  1.000 95.05076  ? 210 ASN H ND2 1 
ATOM   1583 N N   . VAL A 1 211 ? 21.18993 13.64492  64.35470  1.000 87.56672  ? 211 VAL H N   1 
ATOM   1584 C CA  . VAL A 1 211 ? 21.42385 12.84162  63.16110  1.000 84.79626  ? 211 VAL H CA  1 
ATOM   1585 C C   . VAL A 1 211 ? 21.38482 11.37286  63.55609  1.000 79.94251  ? 211 VAL H C   1 
ATOM   1586 O O   . VAL A 1 211 ? 22.10059 10.95253  64.47237  1.000 94.08453  ? 211 VAL H O   1 
ATOM   1587 C CB  . VAL A 1 211 ? 22.76722 13.19361  62.49608  1.000 78.05618  ? 211 VAL H CB  1 
ATOM   1588 C CG1 . VAL A 1 211 ? 23.05469 12.24636  61.34195  1.000 93.50034  ? 211 VAL H CG1 1 
ATOM   1589 C CG2 . VAL A 1 211 ? 22.76180 14.63898  62.02260  1.000 85.36985  ? 211 VAL H CG2 1 
ATOM   1590 N N   . ASN A 1 212 ? 20.55225 10.59672  62.86566  1.000 77.51096  ? 212 ASN H N   1 
ATOM   1591 C CA  . ASN A 1 212 ? 20.40787 9.16585   63.11588  1.000 96.32434  ? 212 ASN H CA  1 
ATOM   1592 C C   . ASN A 1 212 ? 20.66215 8.41827   61.81338  1.000 104.48121 ? 212 ASN H C   1 
ATOM   1593 O O   . ASN A 1 212 ? 19.88305 8.53692   60.86130  1.000 97.10558  ? 212 ASN H O   1 
ATOM   1594 C CB  . ASN A 1 212 ? 19.02164 8.84297   63.67251  1.000 99.65990  ? 212 ASN H CB  1 
ATOM   1595 C CG  . ASN A 1 212 ? 18.68399 7.36728   63.57565  1.000 115.11680 ? 212 ASN H CG  1 
ATOM   1596 O OD1 . ASN A 1 212 ? 19.36229 6.52320   64.16093  1.000 111.78511 ? 212 ASN H OD1 1 
ATOM   1597 N ND2 . ASN A 1 212 ? 17.63100 7.04887   62.83131  1.000 111.92807 ? 212 ASN H ND2 1 
ATOM   1598 N N   . HIS A 1 213 ? 21.74633 7.65003   61.77304  1.000 108.64052 ? 213 HIS H N   1 
ATOM   1599 C CA  . HIS A 1 213 ? 22.10651 6.83627   60.61415  1.000 96.00445  ? 213 HIS H CA  1 
ATOM   1600 C C   . HIS A 1 213 ? 21.87449 5.37594   60.99705  1.000 93.80972  ? 213 HIS H C   1 
ATOM   1601 O O   . HIS A 1 213 ? 22.76842 4.70077   61.51029  1.000 90.14939  ? 213 HIS H O   1 
ATOM   1602 C CB  . HIS A 1 213 ? 23.54943 7.09271   60.18590  1.000 101.12605 ? 213 HIS H CB  1 
ATOM   1603 C CG  . HIS A 1 213 ? 23.93442 6.40436   58.91314  1.000 94.26925  ? 213 HIS H CG  1 
ATOM   1604 N ND1 . HIS A 1 213 ? 24.97990 5.50963   58.83728  1.000 97.22049  ? 213 HIS H ND1 1 
ATOM   1605 C CD2 . HIS A 1 213 ? 23.41377 6.48036   57.66544  1.000 88.61839  ? 213 HIS H CD2 1 
ATOM   1606 C CE1 . HIS A 1 213 ? 25.08679 5.06368   57.59841  1.000 94.16438  ? 213 HIS H CE1 1 
ATOM   1607 N NE2 . HIS A 1 213 ? 24.14800 5.63695   56.86729  1.000 92.15995  ? 213 HIS H NE2 1 
ATOM   1608 N N   . LYS A 1 214 ? 20.65499 4.90060   60.74751  1.000 92.00351  ? 214 LYS H N   1 
ATOM   1609 C CA  . LYS A 1 214 ? 20.29719 3.52977   61.10451  1.000 102.91379 ? 214 LYS H CA  1 
ATOM   1610 C C   . LYS A 1 214 ? 21.17656 2.45985   60.45972  1.000 107.26179 ? 214 LYS H C   1 
ATOM   1611 O O   . LYS A 1 214 ? 21.49914 1.47933   61.15355  1.000 103.12055 ? 214 LYS H O   1 
ATOM   1612 C CB  . LYS A 1 214 ? 18.81813 3.28394   60.77934  1.000 101.20606 ? 214 LYS H CB  1 
ATOM   1613 C CG  . LYS A 1 214 ? 17.89397 3.45560   61.97536  1.000 109.06067 ? 214 LYS H CG  1 
ATOM   1614 C CD  . LYS A 1 214 ? 18.30774 2.54619   63.12325  1.000 109.27418 ? 214 LYS H CD  1 
ATOM   1615 C CE  . LYS A 1 214 ? 17.15735 2.30854   64.08837  1.000 93.19473  ? 214 LYS H CE  1 
ATOM   1616 N NZ  . LYS A 1 214 ? 16.93511 3.47453   64.98785  1.000 83.50616  ? 214 LYS H NZ  1 
ATOM   1617 N N   . PRO A 1 215 ? 21.57471 2.54926   59.18128  1.000 99.05574  ? 215 PRO H N   1 
ATOM   1618 C CA  . PRO A 1 215 ? 22.41888 1.47677   58.61823  1.000 91.00509  ? 215 PRO H CA  1 
ATOM   1619 C C   . PRO A 1 215 ? 23.70894 1.24049   59.38650  1.000 105.41755 ? 215 PRO H C   1 
ATOM   1620 O O   . PRO A 1 215 ? 24.21884 0.11303   59.38197  1.000 109.14117 ? 215 PRO H O   1 
ATOM   1621 C CB  . PRO A 1 215 ? 22.70296 1.94559   57.18358  1.000 100.48053 ? 215 PRO H CB  1 
ATOM   1622 C CG  . PRO A 1 215 ? 21.74578 3.02075   56.89343  1.000 107.35686 ? 215 PRO H CG  1 
ATOM   1623 C CD  . PRO A 1 215 ? 21.12979 3.51169   58.15513  1.000 96.50991  ? 215 PRO H CD  1 
ATOM   1624 N N   . SER A 1 216 ? 24.25952 2.26194   60.04008  1.000 110.66646 ? 216 SER H N   1 
ATOM   1625 C CA  . SER A 1 216 ? 25.43021 2.09265   60.88928  1.000 104.81918 ? 216 SER H CA  1 
ATOM   1626 C C   . SER A 1 216 ? 25.10772 2.20041   62.37287  1.000 104.22902 ? 216 SER H C   1 
ATOM   1627 O O   . SER A 1 216 ? 26.02637 2.12344   63.19630  1.000 119.30450 ? 216 SER H O   1 
ATOM   1628 C CB  . SER A 1 216 ? 26.50822 3.11907   60.52198  1.000 99.09285  ? 216 SER H CB  1 
ATOM   1629 O OG  . SER A 1 216 ? 26.09542 4.43260   60.85469  1.000 97.00600  ? 216 SER H OG  1 
ATOM   1630 N N   . ASN A 1 217 ? 23.83227 2.37115   62.73297  1.000 111.57936 ? 217 ASN H N   1 
ATOM   1631 C CA  . ASN A 1 217 ? 23.41003 2.53233   64.12718  1.000 117.75566 ? 217 ASN H CA  1 
ATOM   1632 C C   . ASN A 1 217 ? 24.15484 3.68163   64.80264  1.000 108.15325 ? 217 ASN H C   1 
ATOM   1633 O O   . ASN A 1 217 ? 24.51514 3.60782   65.97916  1.000 112.91716 ? 217 ASN H O   1 
ATOM   1634 C CB  . ASN A 1 217 ? 23.58388 1.23264   64.91780  1.000 123.91545 ? 217 ASN H CB  1 
ATOM   1635 C CG  . ASN A 1 217 ? 23.01694 0.02832   64.19275  1.000 148.59546 ? 217 ASN H CG  1 
ATOM   1636 O OD1 . ASN A 1 217 ? 21.81027 -0.06298  63.96658  1.000 152.38900 ? 217 ASN H OD1 1 
ATOM   1637 N ND2 . ASN A 1 217 ? 23.88720 -0.90552  63.82550  1.000 153.21077 ? 217 ASN H ND2 1 
ATOM   1638 N N   . THR A 1 218 ? 24.38639 4.75477   64.05119  1.000 109.15902 ? 218 THR H N   1 
ATOM   1639 C CA  . THR A 1 218 ? 25.12364 5.91788   64.53234  1.000 111.24593 ? 218 THR H CA  1 
ATOM   1640 C C   . THR A 1 218 ? 24.13272 7.04552   64.79260  1.000 107.68591 ? 218 THR H C   1 
ATOM   1641 O O   . THR A 1 218 ? 23.49393 7.54591   63.86072  1.000 104.57313 ? 218 THR H O   1 
ATOM   1642 C CB  . THR A 1 218 ? 26.18734 6.34813   63.52372  1.000 82.83682  ? 218 THR H CB  1 
ATOM   1643 O OG1 . THR A 1 218 ? 27.03482 5.23476   63.21409  1.000 100.25363 ? 218 THR H OG1 1 
ATOM   1644 C CG2 . THR A 1 218 ? 27.03334 7.47804   64.09115  1.000 77.48558  ? 218 THR H CG2 1 
ATOM   1645 N N   . LYS A 1 219 ? 24.00548 7.44112   66.05659  1.000 99.47024  ? 219 LYS H N   1 
ATOM   1646 C CA  . LYS A 1 219 ? 23.17282 8.56963   66.45284  1.000 102.71418 ? 219 LYS H CA  1 
ATOM   1647 C C   . LYS A 1 219 ? 24.05458 9.59355   67.15090  1.000 108.85849 ? 219 LYS H C   1 
ATOM   1648 O O   . LYS A 1 219 ? 24.70254 9.27729   68.15452  1.000 114.30002 ? 219 LYS H O   1 
ATOM   1649 C CB  . LYS A 1 219 ? 22.03056 8.12269   67.36729  1.000 117.98829 ? 219 LYS H CB  1 
ATOM   1650 C CG  . LYS A 1 219 ? 21.16999 7.01044   66.78850  1.000 101.35137 ? 219 LYS H CG  1 
ATOM   1651 C CD  . LYS A 1 219 ? 19.86480 6.85799   67.55695  1.000 107.93049 ? 219 LYS H CD  1 
ATOM   1652 C CE  . LYS A 1 219 ? 19.25202 8.21173   67.88854  1.000 115.85599 ? 219 LYS H CE  1 
ATOM   1653 N NZ  . LYS A 1 219 ? 18.14928 8.10119   68.88382  1.000 94.92773  ? 219 LYS H NZ  1 
ATOM   1654 N N   . VAL A 1 220 ? 24.07968 10.81317  66.62039  1.000 103.53258 ? 220 VAL H N   1 
ATOM   1655 C CA  . VAL A 1 220 ? 24.92604 11.87983  67.14153  1.000 105.10434 ? 220 VAL H CA  1 
ATOM   1656 C C   . VAL A 1 220 ? 24.13802 13.18178  67.14209  1.000 91.91680  ? 220 VAL H C   1 
ATOM   1657 O O   . VAL A 1 220 ? 23.39420 13.47267  66.19926  1.000 90.95161  ? 220 VAL H O   1 
ATOM   1658 C CB  . VAL A 1 220 ? 26.22498 12.02348  66.32204  1.000 89.10177  ? 220 VAL H CB  1 
ATOM   1659 C CG1 . VAL A 1 220 ? 27.22649 10.95482  66.72661  1.000 109.32189 ? 220 VAL H CG1 1 
ATOM   1660 C CG2 . VAL A 1 220 ? 25.92195 11.92447  64.83938  1.000 83.99592  ? 220 VAL H CG2 1 
ATOM   1661 N N   . ASP A 1 221 ? 24.30075 13.96282  68.20689  1.000 97.44789  ? 221 ASP H N   1 
ATOM   1662 C CA  . ASP A 1 221 ? 23.66464 15.26552  68.34430  1.000 102.15517 ? 221 ASP H CA  1 
ATOM   1663 C C   . ASP A 1 221 ? 24.74663 16.32998  68.44116  1.000 102.36750 ? 221 ASP H C   1 
ATOM   1664 O O   . ASP A 1 221 ? 25.70095 16.18070  69.21165  1.000 107.49146 ? 221 ASP H O   1 
ATOM   1665 C CB  . ASP A 1 221 ? 22.75727 15.31002  69.57671  1.000 100.66292 ? 221 ASP H CB  1 
ATOM   1666 C CG  . ASP A 1 221 ? 21.86596 14.08883  69.68706  1.000 113.42210 ? 221 ASP H CG  1 
ATOM   1667 O OD1 . ASP A 1 221 ? 21.29151 13.67583  68.65780  1.000 113.33266 ? 221 ASP H OD1 1 
ATOM   1668 O OD2 . ASP A 1 221 ? 21.74139 13.54021  70.80243  1.000 117.30482 ? 221 ASP H OD2 1 
ATOM   1669 N N   . LYS A 1 222 ? 24.59701 17.39981  67.66466  1.000 107.25743 ? 222 LYS H N   1 
ATOM   1670 C CA  . LYS A 1 222 ? 25.60371 18.44756  67.57029  1.000 100.62383 ? 222 LYS H CA  1 
ATOM   1671 C C   . LYS A 1 222 ? 24.98391 19.79588  67.90403  1.000 93.51295  ? 222 LYS H C   1 
ATOM   1672 O O   . LYS A 1 222 ? 23.92873 20.14940  67.36795  1.000 95.44306  ? 222 LYS H O   1 
ATOM   1673 C CB  . LYS A 1 222 ? 26.22388 18.48469  66.17182  1.000 98.87923  ? 222 LYS H CB  1 
ATOM   1674 C CG  . LYS A 1 222 ? 27.38535 19.44964  66.04498  1.000 103.12579 ? 222 LYS H CG  1 
ATOM   1675 C CD  . LYS A 1 222 ? 28.53126 19.01770  66.93931  1.000 107.71731 ? 222 LYS H CD  1 
ATOM   1676 C CE  . LYS A 1 222 ? 29.28903 17.85061  66.33458  1.000 108.57155 ? 222 LYS H CE  1 
ATOM   1677 N NZ  . LYS A 1 222 ? 30.75728 18.04632  66.43186  1.000 116.55683 ? 222 LYS H NZ  1 
ATOM   1678 N N   . ARG A 1 223 ? 25.64529 20.54532  68.78167  1.000 83.88911  ? 223 ARG H N   1 
ATOM   1679 C CA  . ARG A 1 223 ? 25.22146 21.89423  69.12828  1.000 88.73168  ? 223 ARG H CA  1 
ATOM   1680 C C   . ARG A 1 223 ? 25.88491 22.89281  68.18983  1.000 86.15034  ? 223 ARG H C   1 
ATOM   1681 O O   . ARG A 1 223 ? 27.11325 22.91499  68.06445  1.000 86.32102  ? 223 ARG H O   1 
ATOM   1682 C CB  . ARG A 1 223 ? 25.57727 22.22056  70.57921  1.000 111.80003 ? 223 ARG H CB  1 
ATOM   1683 C CG  . ARG A 1 223 ? 24.73740 23.33190  71.18959  1.000 115.77873 ? 223 ARG H CG  1 
ATOM   1684 C CD  . ARG A 1 223 ? 25.02512 23.49043  72.67316  1.000 111.05953 ? 223 ARG H CD  1 
ATOM   1685 N NE  . ARG A 1 223 ? 25.20956 22.20427  73.33432  1.000 134.57274 ? 223 ARG H NE  1 
ATOM   1686 C CZ  . ARG A 1 223 ? 25.08652 22.00899  74.64006  1.000 146.91739 ? 223 ARG H CZ  1 
ATOM   1687 N NH1 . ARG A 1 223 ? 24.78184 23.00037  75.46164  1.000 134.73441 ? 223 ARG H NH1 1 
ATOM   1688 N NH2 . ARG A 1 223 ? 25.27527 20.78868  75.13421  1.000 136.61553 ? 223 ARG H NH2 1 
ATOM   1689 N N   . VAL A 1 224 ? 25.07283 23.71523  67.53610  1.000 86.22952  ? 224 VAL H N   1 
ATOM   1690 C CA  . VAL A 1 224 ? 25.55787 24.73163  66.60995  1.000 91.42809  ? 224 VAL H CA  1 
ATOM   1691 C C   . VAL A 1 224 ? 25.55546 26.06565  67.34382  1.000 86.32126  ? 224 VAL H C   1 
ATOM   1692 O O   . VAL A 1 224 ? 24.49819 26.67051  67.55071  1.000 92.36177  ? 224 VAL H O   1 
ATOM   1693 C CB  . VAL A 1 224 ? 24.70541 24.79286  65.33545  1.000 85.90623  ? 224 VAL H CB  1 
ATOM   1694 C CG1 . VAL A 1 224 ? 25.43630 25.56316  64.24994  1.000 84.02319  ? 224 VAL H CG1 1 
ATOM   1695 C CG2 . VAL A 1 224 ? 24.36401 23.38972  64.85503  1.000 78.37346  ? 224 VAL H CG2 1 
ATOM   1696 N N   . GLU A 1 225 ? 26.74143 26.53197  67.72808  1.000 94.11354  ? 225 GLU H N   1 
ATOM   1697 C CA  . GLU A 1 225 ? 26.90338 27.77556  68.46087  1.000 104.30605 ? 225 GLU H CA  1 
ATOM   1698 C C   . GLU A 1 225 ? 27.55787 28.83285  67.57616  1.000 85.98740  ? 225 GLU H C   1 
ATOM   1699 O O   . GLU A 1 225 ? 28.33278 28.49776  66.67467  1.000 84.05423  ? 225 GLU H O   1 
ATOM   1700 C CB  . GLU A 1 225 ? 27.75115 27.55929  69.72083  1.000 103.81607 ? 225 GLU H CB  1 
ATOM   1701 C CG  . GLU A 1 225 ? 26.93711 27.15911  70.94184  1.000 110.92676 ? 225 GLU H CG  1 
ATOM   1702 C CD  . GLU A 1 225 ? 27.74160 26.35665  71.94492  1.000 135.30906 ? 225 GLU H CD  1 
ATOM   1703 O OE1 . GLU A 1 225 ? 28.34661 25.33960  71.54516  1.000 114.37725 ? 225 GLU H OE1 1 
ATOM   1704 O OE2 . GLU A 1 225 ? 27.76441 26.73963  73.13401  1.000 155.91824 ? 225 GLU H OE2 1 
ATOM   1705 N N   . PRO A 1 226 ? 27.25376 30.12165  67.79799  1.000 80.68339  ? 226 PRO H N   1 
ATOM   1706 C CA  . PRO A 1 226 ? 27.77492 31.17053  66.90824  1.000 101.73161 ? 226 PRO H CA  1 
ATOM   1707 C C   . PRO A 1 226 ? 29.29361 31.21527  66.83586  1.000 100.93748 ? 226 PRO H C   1 
ATOM   1708 O O   . PRO A 1 226 ? 29.87100 31.02439  65.76127  1.000 110.50257 ? 226 PRO H O   1 
ATOM   1709 C CB  . PRO A 1 226 ? 27.21169 32.45657  67.52774  1.000 71.39053  ? 226 PRO H CB  1 
ATOM   1710 C CG  . PRO A 1 226 ? 25.97424 32.01028  68.23550  1.000 76.16733  ? 226 PRO H CG  1 
ATOM   1711 C CD  . PRO A 1 226 ? 26.33483 30.67149  68.80941  1.000 81.00728  ? 226 PRO H CD  1 
ATOM   1712 N N   . LYS A 1 227 ? 29.94873 31.44023  67.97055  1.000 100.41879 ? 227 LYS H N   1 
ATOM   1713 C CA  . LYS A 1 227 ? 31.40465 31.54550  68.00753  1.000 124.45684 ? 227 LYS H CA  1 
ATOM   1714 C C   . LYS A 1 227 ? 31.95345 31.08988  69.35495  1.000 137.34186 ? 227 LYS H C   1 
ATOM   1715 O O   . LYS A 1 227 ? 32.59023 31.86402  70.07085  1.000 132.19720 ? 227 LYS H O   1 
ATOM   1716 C CB  . LYS A 1 227 ? 31.85426 32.98627  67.71979  1.000 119.66925 ? 227 LYS H CB  1 
ATOM   1717 C CG  . LYS A 1 227 ? 31.94050 33.37880  66.23783  1.000 113.87168 ? 227 LYS H CG  1 
ATOM   1718 C CD  . LYS A 1 227 ? 32.72687 32.39205  65.36742  1.000 125.15204 ? 227 LYS H CD  1 
ATOM   1719 C CE  . LYS A 1 227 ? 34.08208 32.01883  65.96482  1.000 135.45782 ? 227 LYS H CE  1 
ATOM   1720 N NZ  . LYS A 1 227 ? 34.72807 30.90124  65.22113  1.000 143.15751 ? 227 LYS H NZ  1 
ATOM   1721 N N   . SER B 2 2   ? 28.84833 13.79786  15.69292  1.000 117.03735 ? 2   SER L N   1 
ATOM   1722 C CA  . SER B 2 2   ? 28.10073 15.04741  15.76481  1.000 111.47730 ? 2   SER L CA  1 
ATOM   1723 C C   . SER B 2 2   ? 27.80656 15.43122  17.21105  1.000 116.02404 ? 2   SER L C   1 
ATOM   1724 O O   . SER B 2 2   ? 27.81931 14.58372  18.10406  1.000 117.53104 ? 2   SER L O   1 
ATOM   1725 C CB  . SER B 2 2   ? 26.79370 14.93677  14.97633  1.000 114.66292 ? 2   SER L CB  1 
ATOM   1726 O OG  . SER B 2 2   ? 27.03304 14.97687  13.58063  1.000 128.07390 ? 2   SER L OG  1 
ATOM   1727 N N   . VAL B 2 3   ? 27.54559 16.71683  17.43503  1.000 108.93827 ? 3   VAL L N   1 
ATOM   1728 C CA  . VAL B 2 3   ? 27.18697 17.23695  18.74830  1.000 88.86170  ? 3   VAL L CA  1 
ATOM   1729 C C   . VAL B 2 3   ? 25.90312 18.04096  18.60237  1.000 96.96678  ? 3   VAL L C   1 
ATOM   1730 O O   . VAL B 2 3   ? 25.82292 18.94335  17.76113  1.000 95.95034  ? 3   VAL L O   1 
ATOM   1731 C CB  . VAL B 2 3   ? 28.31222 18.10283  19.34891  1.000 76.36910  ? 3   VAL L CB  1 
ATOM   1732 C CG1 . VAL B 2 3   ? 27.74747 19.11762  20.33564  1.000 93.34897  ? 3   VAL L CG1 1 
ATOM   1733 C CG2 . VAL B 2 3   ? 29.35670 17.22333  20.01901  1.000 70.18723  ? 3   VAL L CG2 1 
ATOM   1734 N N   . LEU B 2 4   ? 24.90194 17.71031  19.41260  1.000 90.90319  ? 4   LEU L N   1 
ATOM   1735 C CA  . LEU B 2 4   ? 23.61027 18.38225  19.38946  1.000 89.92878  ? 4   LEU L CA  1 
ATOM   1736 C C   . LEU B 2 4   ? 23.45563 19.21865  20.65137  1.000 91.62001  ? 4   LEU L C   1 
ATOM   1737 O O   . LEU B 2 4   ? 23.59933 18.70249  21.76486  1.000 110.70988 ? 4   LEU L O   1 
ATOM   1738 C CB  . LEU B 2 4   ? 22.46770 17.37084  19.27526  1.000 86.03991  ? 4   LEU L CB  1 
ATOM   1739 C CG  . LEU B 2 4   ? 22.50627 16.44482  18.05727  1.000 75.39131  ? 4   LEU L CG  1 
ATOM   1740 C CD1 . LEU B 2 4   ? 21.38824 15.41637  18.12771  1.000 69.02885  ? 4   LEU L CD1 1 
ATOM   1741 C CD2 . LEU B 2 4   ? 22.42252 17.24616  16.76892  1.000 78.94406  ? 4   LEU L CD2 1 
ATOM   1742 N N   . THR B 2 5   ? 23.16191 20.50342  20.47434  1.000 85.10182  ? 5   THR L N   1 
ATOM   1743 C CA  . THR B 2 5   ? 23.04807 21.44952  21.57563  1.000 78.91605  ? 5   THR L CA  1 
ATOM   1744 C C   . THR B 2 5   ? 21.58143 21.77357  21.82359  1.000 79.29856  ? 5   THR L C   1 
ATOM   1745 O O   . THR B 2 5   ? 20.85042 22.12182  20.89002  1.000 78.94239  ? 5   THR L O   1 
ATOM   1746 C CB  . THR B 2 5   ? 23.83003 22.73115  21.27903  1.000 72.33271  ? 5   THR L CB  1 
ATOM   1747 O OG1 . THR B 2 5   ? 25.19628 22.40387  20.99667  1.000 77.31165  ? 5   THR L OG1 1 
ATOM   1748 C CG2 . THR B 2 5   ? 23.77960 23.67390  22.46957  1.000 64.37448  ? 5   THR L CG2 1 
ATOM   1749 N N   . GLN B 2 6   ? 21.15911 21.65970  23.08163  1.000 71.83577  ? 6   GLN L N   1 
ATOM   1750 C CA  . GLN B 2 6   ? 19.79242 21.93278  23.49019  1.000 74.49742  ? 6   GLN L CA  1 
ATOM   1751 C C   . GLN B 2 6   ? 19.79100 22.91337  24.65445  1.000 77.19906  ? 6   GLN L C   1 
ATOM   1752 O O   . GLN B 2 6   ? 20.68944 22.86837  25.50405  1.000 82.87822  ? 6   GLN L O   1 
ATOM   1753 C CB  . GLN B 2 6   ? 19.07669 20.63877  23.90537  1.000 70.37750  ? 6   GLN L CB  1 
ATOM   1754 C CG  . GLN B 2 6   ? 18.39800 19.89981  22.76627  1.000 88.45065  ? 6   GLN L CG  1 
ATOM   1755 C CD  . GLN B 2 6   ? 17.70316 18.63429  23.23047  1.000 83.25368  ? 6   GLN L CD  1 
ATOM   1756 O OE1 . GLN B 2 6   ? 18.32334 17.57626  23.33902  1.000 71.11888  ? 6   GLN L OE1 1 
ATOM   1757 N NE2 . GLN B 2 6   ? 16.40994 18.73859  23.51404  1.000 88.50054  ? 6   GLN L NE2 1 
ATOM   1758 N N   . PRO B 2 7   ? 18.81583 23.81605  24.71511  1.000 72.91774  ? 7   PRO L N   1 
ATOM   1759 C CA  . PRO B 2 7   ? 18.69950 24.70691  25.87375  1.000 72.06563  ? 7   PRO L CA  1 
ATOM   1760 C C   . PRO B 2 7   ? 18.47080 23.90718  27.14243  1.000 86.06229  ? 7   PRO L C   1 
ATOM   1761 O O   . PRO B 2 7   ? 17.73040 22.91244  27.13221  1.000 72.11122  ? 7   PRO L O   1 
ATOM   1762 C CB  . PRO B 2 7   ? 17.47878 25.57974  25.53718  1.000 67.86522  ? 7   PRO L CB  1 
ATOM   1763 C CG  . PRO B 2 7   ? 16.77436 24.87124  24.42641  1.000 81.19460  ? 7   PRO L CG  1 
ATOM   1764 C CD  . PRO B 2 7   ? 17.82562 24.12873  23.67367  1.000 85.31043  ? 7   PRO L CD  1 
ATOM   1765 N N   . PRO B 2 8   ? 19.10007 24.29867  28.25271  1.000 77.91612  ? 8   PRO L N   1 
ATOM   1766 C CA  . PRO B 2 8   ? 18.89253 23.55795  29.50755  1.000 44.65771  ? 8   PRO L CA  1 
ATOM   1767 C C   . PRO B 2 8   ? 17.45141 23.56119  29.98931  1.000 64.15863  ? 8   PRO L C   1 
ATOM   1768 O O   . PRO B 2 8   ? 17.00595 22.56893  30.57971  1.000 58.08310  ? 8   PRO L O   1 
ATOM   1769 C CB  . PRO B 2 8   ? 19.82314 24.28004  30.49276  1.000 71.55889  ? 8   PRO L CB  1 
ATOM   1770 C CG  . PRO B 2 8   ? 20.85046 24.94032  29.62324  1.000 61.52717  ? 8   PRO L CG  1 
ATOM   1771 C CD  . PRO B 2 8   ? 20.09366 25.37281  28.40749  1.000 77.59335  ? 8   PRO L CD  1 
ATOM   1772 N N   . SER B 2 9   ? 16.70590 24.64045  29.75780  1.000 59.21513  ? 9   SER L N   1 
ATOM   1773 C CA  . SER B 2 9   ? 15.32517 24.72018  30.21222  1.000 63.69150  ? 9   SER L CA  1 
ATOM   1774 C C   . SER B 2 9   ? 14.55240 25.69093  29.33196  1.000 81.96683  ? 9   SER L C   1 
ATOM   1775 O O   . SER B 2 9   ? 15.09332 26.70996  28.89384  1.000 82.83867  ? 9   SER L O   1 
ATOM   1776 C CB  . SER B 2 9   ? 15.24283 25.15955  31.67947  1.000 74.47311  ? 9   SER L CB  1 
ATOM   1777 O OG  . SER B 2 9   ? 15.87464 26.41282  31.87708  1.000 75.28335  ? 9   SER L OG  1 
ATOM   1778 N N   . VAL B 2 10  ? 13.28723 25.36272  29.07719  1.000 70.66031  ? 10  VAL L N   1 
ATOM   1779 C CA  . VAL B 2 10  ? 12.37805 26.21150  28.31661  1.000 59.30761  ? 10  VAL L CA  1 
ATOM   1780 C C   . VAL B 2 10  ? 11.08427 26.34165  29.10748  1.000 69.50520  ? 10  VAL L C   1 
ATOM   1781 O O   . VAL B 2 10  ? 10.49775 25.33280  29.51496  1.000 73.91957  ? 10  VAL L O   1 
ATOM   1782 C CB  . VAL B 2 10  ? 12.10461 25.64376  26.90982  1.000 73.28521  ? 10  VAL L CB  1 
ATOM   1783 C CG1 . VAL B 2 10  ? 10.83646 26.24732  26.32184  1.000 71.35455  ? 10  VAL L CG1 1 
ATOM   1784 C CG2 . VAL B 2 10  ? 13.29418 25.89466  25.99660  1.000 54.83880  ? 10  VAL L CG2 1 
ATOM   1785 N N   . SER B 2 11  ? 10.64163 27.57711  29.32260  1.000 83.20832  ? 11  SER L N   1 
ATOM   1786 C CA  . SER B 2 11  ? 9.45955  27.86693  30.12281  1.000 69.92025  ? 11  SER L CA  1 
ATOM   1787 C C   . SER B 2 11  ? 8.33129  28.34003  29.21835  1.000 83.77465  ? 11  SER L C   1 
ATOM   1788 O O   . SER B 2 11  ? 8.53254  29.22291  28.37759  1.000 100.67276 ? 11  SER L O   1 
ATOM   1789 C CB  . SER B 2 11  ? 9.76517  28.92754  31.18155  1.000 68.92594  ? 11  SER L CB  1 
ATOM   1790 O OG  . SER B 2 11  ? 10.63024 28.41262  32.17628  1.000 99.20944  ? 11  SER L OG  1 
ATOM   1791 N N   . VAL B 2 12  ? 7.15110  27.75097  29.38991  1.000 81.43198  ? 12  VAL L N   1 
ATOM   1792 C CA  . VAL B 2 12  ? 5.96950  28.12762  28.62366  1.000 90.71184  ? 12  VAL L CA  1 
ATOM   1793 C C   . VAL B 2 12  ? 4.76507  28.14261  29.55589  1.000 91.54590  ? 12  VAL L C   1 
ATOM   1794 O O   . VAL B 2 12  ? 4.60124  27.25001  30.39487  1.000 78.23893  ? 12  VAL L O   1 
ATOM   1795 C CB  . VAL B 2 12  ? 5.74278  27.17830  27.42542  1.000 70.60932  ? 12  VAL L CB  1 
ATOM   1796 C CG1 . VAL B 2 12  ? 5.60413  25.73401  27.89109  1.000 79.34689  ? 12  VAL L CG1 1 
ATOM   1797 C CG2 . VAL B 2 12  ? 4.52477  27.60820  26.62093  1.000 78.71609  ? 12  VAL L CG2 1 
ATOM   1798 N N   . ALA B 2 13  ? 3.93563  29.17777  29.42660  1.000 84.81286  ? 13  ALA L N   1 
ATOM   1799 C CA  . ALA B 2 13  ? 2.68727  29.22704  30.16683  1.000 76.28527  ? 13  ALA L CA  1 
ATOM   1800 C C   . ALA B 2 13  ? 1.65352  28.31068  29.51505  1.000 87.16675  ? 13  ALA L C   1 
ATOM   1801 O O   . ALA B 2 13  ? 1.70279  28.07344  28.30477  1.000 90.52030  ? 13  ALA L O   1 
ATOM   1802 C CB  . ALA B 2 13  ? 2.15369  30.65418  30.22202  1.000 59.74151  ? 13  ALA L CB  1 
ATOM   1803 N N   . PRO B 2 14  ? 0.72285  27.76584  30.29933  1.000 87.42225  ? 14  PRO L N   1 
ATOM   1804 C CA  . PRO B 2 14  ? -0.31944 26.91336  29.71611  1.000 84.29570  ? 14  PRO L CA  1 
ATOM   1805 C C   . PRO B 2 14  ? -1.10919 27.65540  28.64801  1.000 87.37787  ? 14  PRO L C   1 
ATOM   1806 O O   . PRO B 2 14  ? -1.46330 28.82508  28.80867  1.000 81.92428  ? 14  PRO L O   1 
ATOM   1807 C CB  . PRO B 2 14  ? -1.19692 26.55982  30.92034  1.000 75.13078  ? 14  PRO L CB  1 
ATOM   1808 C CG  . PRO B 2 14  ? -0.25885 26.60375  32.07491  1.000 84.39527  ? 14  PRO L CG  1 
ATOM   1809 C CD  . PRO B 2 14  ? 0.70538  27.72552  31.77227  1.000 83.97504  ? 14  PRO L CD  1 
ATOM   1810 N N   . GLY B 2 15  ? -1.38143 26.95868  27.54600  1.000 88.72585  ? 15  GLY L N   1 
ATOM   1811 C CA  . GLY B 2 15  ? -2.10963 27.52250  26.43507  1.000 83.17313  ? 15  GLY L CA  1 
ATOM   1812 C C   . GLY B 2 15  ? -1.25117 28.13956  25.35088  1.000 83.71114  ? 15  GLY L C   1 
ATOM   1813 O O   . GLY B 2 15  ? -1.73915 28.33368  24.23225  1.000 91.87163  ? 15  GLY L O   1 
ATOM   1814 N N   . GLN B 2 16  ? 0.00894  28.45062  25.64278  1.000 85.74314  ? 16  GLN L N   1 
ATOM   1815 C CA  . GLN B 2 16  ? 0.90399  29.03546  24.65684  1.000 81.96245  ? 16  GLN L CA  1 
ATOM   1816 C C   . GLN B 2 16  ? 1.58720  27.92610  23.85782  1.000 91.27640  ? 16  GLN L C   1 
ATOM   1817 O O   . GLN B 2 16  ? 1.25799  26.74353  23.98269  1.000 93.24522  ? 16  GLN L O   1 
ATOM   1818 C CB  . GLN B 2 16  ? 1.91985  29.95253  25.33461  1.000 75.80967  ? 16  GLN L CB  1 
ATOM   1819 C CG  . GLN B 2 16  ? 1.30649  31.02303  26.21941  1.000 90.70649  ? 16  GLN L CG  1 
ATOM   1820 C CD  . GLN B 2 16  ? 2.35478  31.85733  26.93054  1.000 120.75504 ? 16  GLN L CD  1 
ATOM   1821 O OE1 . GLN B 2 16  ? 3.44084  31.37153  27.24858  1.000 113.39940 ? 16  GLN L OE1 1 
ATOM   1822 N NE2 . GLN B 2 16  ? 2.03418  33.12147  27.18305  1.000 124.19486 ? 16  GLN L NE2 1 
ATOM   1823 N N   . THR B 2 17  ? 2.55076  28.30329  23.02130  1.000 90.79956  ? 17  THR L N   1 
ATOM   1824 C CA  . THR B 2 17  ? 3.28401  27.36763  22.18025  1.000 88.68477  ? 17  THR L CA  1 
ATOM   1825 C C   . THR B 2 17  ? 4.76084  27.41967  22.54331  1.000 81.24971  ? 17  THR L C   1 
ATOM   1826 O O   . THR B 2 17  ? 5.35428  28.50240  22.59083  1.000 78.67880  ? 17  THR L O   1 
ATOM   1827 C CB  . THR B 2 17  ? 3.08793  27.69190  20.69592  1.000 86.88072  ? 17  THR L CB  1 
ATOM   1828 O OG1 . THR B 2 17  ? 1.70127  27.56404  20.35700  1.000 81.10832  ? 17  THR L OG1 1 
ATOM   1829 C CG2 . THR B 2 17  ? 3.90268  26.74509  19.82923  1.000 87.85025  ? 17  THR L CG2 1 
ATOM   1830 N N   . ALA B 2 18  ? 5.34887  26.25256  22.79213  1.000 71.97755  ? 18  ALA L N   1 
ATOM   1831 C CA  . ALA B 2 18  ? 6.74402  26.13613  23.18971  1.000 55.86870  ? 18  ALA L CA  1 
ATOM   1832 C C   . ALA B 2 18  ? 7.55652  25.50159  22.06994  1.000 72.25755  ? 18  ALA L C   1 
ATOM   1833 O O   . ALA B 2 18  ? 7.10561  24.54994  21.42444  1.000 82.92911  ? 18  ALA L O   1 
ATOM   1834 C CB  . ALA B 2 18  ? 6.88376  25.30541  24.46674  1.000 79.45949  ? 18  ALA L CB  1 
ATOM   1835 N N   . THR B 2 19  ? 8.75690  26.03193  21.84646  1.000 71.22181  ? 19  THR L N   1 
ATOM   1836 C CA  . THR B 2 19  ? 9.65009  25.56194  20.79427  1.000 80.04543  ? 19  THR L CA  1 
ATOM   1837 C C   . THR B 2 19  ? 10.99160 25.19120  21.40908  1.000 67.84055  ? 19  THR L C   1 
ATOM   1838 O O   . THR B 2 19  ? 11.62207 26.01861  22.07597  1.000 74.38371  ? 19  THR L O   1 
ATOM   1839 C CB  . THR B 2 19  ? 9.83425  26.62932  19.71276  1.000 93.06419  ? 19  THR L CB  1 
ATOM   1840 O OG1 . THR B 2 19  ? 8.61492  26.78235  18.97525  1.000 104.79292 ? 19  THR L OG1 1 
ATOM   1841 C CG2 . THR B 2 19  ? 10.95457 26.23964  18.76129  1.000 88.24301  ? 19  THR L CG2 1 
ATOM   1842 N N   . ILE B 2 20  ? 11.42888 23.95658  21.17461  1.000 70.90170  ? 20  ILE L N   1 
ATOM   1843 C CA  . ILE B 2 20  ? 12.70573 23.45316  21.66824  1.000 85.68515  ? 20  ILE L CA  1 
ATOM   1844 C C   . ILE B 2 20  ? 13.66268 23.35700  20.48902  1.000 78.13248  ? 20  ILE L C   1 
ATOM   1845 O O   . ILE B 2 20  ? 13.29006 22.86535  19.41686  1.000 74.60578  ? 20  ILE L O   1 
ATOM   1846 C CB  . ILE B 2 20  ? 12.54612 22.09324  22.37084  1.000 91.51356  ? 20  ILE L CB  1 
ATOM   1847 C CG1 . ILE B 2 20  ? 11.65711 22.23566  23.60792  1.000 71.16306  ? 20  ILE L CG1 1 
ATOM   1848 C CG2 . ILE B 2 20  ? 13.90236 21.52753  22.76370  1.000 81.82084  ? 20  ILE L CG2 1 
ATOM   1849 C CD1 . ILE B 2 20  ? 10.70545 21.07870  23.81350  1.000 86.59211  ? 20  ILE L CD1 1 
ATOM   1850 N N   . THR B 2 21  ? 14.88977 23.82867  20.68608  1.000 79.14232  ? 21  THR L N   1 
ATOM   1851 C CA  . THR B 2 21  ? 15.87436 23.95038  19.62204  1.000 69.49880  ? 21  THR L CA  1 
ATOM   1852 C C   . THR B 2 21  ? 16.97659 22.91271  19.79524  1.000 80.40936  ? 21  THR L C   1 
ATOM   1853 O O   . THR B 2 21  ? 17.45324 22.67880  20.90992  1.000 87.93441  ? 21  THR L O   1 
ATOM   1854 C CB  . THR B 2 21  ? 16.47998 25.35644  19.60929  1.000 77.30723  ? 21  THR L CB  1 
ATOM   1855 O OG1 . THR B 2 21  ? 15.43017 26.32886  19.53311  1.000 98.25916  ? 21  THR L OG1 1 
ATOM   1856 C CG2 . THR B 2 21  ? 17.39186 25.52785  18.41939  1.000 88.46627  ? 21  THR L CG2 1 
ATOM   1857 N N   . CYS B 2 22  ? 17.37413 22.28823  18.68680  1.000 71.64346  ? 22  CYS L N   1 
ATOM   1858 C CA  . CYS B 2 22  ? 18.46569 21.31755  18.66834  1.000 75.14448  ? 22  CYS L CA  1 
ATOM   1859 C C   . CYS B 2 22  ? 19.37820 21.66164  17.49819  1.000 74.84156  ? 22  CYS L C   1 
ATOM   1860 O O   . CYS B 2 22  ? 18.99168 21.49494  16.33740  1.000 90.81749  ? 22  CYS L O   1 
ATOM   1861 C CB  . CYS B 2 22  ? 17.92955 19.88935  18.55385  1.000 90.64278  ? 22  CYS L CB  1 
ATOM   1862 S SG  . CYS B 2 22  ? 19.18788 18.60396  18.37477  1.000 89.24833  ? 22  CYS L SG  1 
ATOM   1863 N N   . GLY B 2 23  ? 20.58769 22.13823  17.80093  1.000 78.28690  ? 23  GLY L N   1 
ATOM   1864 C CA  . GLY B 2 23  ? 21.48541 22.65863  16.79409  1.000 84.92811  ? 23  GLY L CA  1 
ATOM   1865 C C   . GLY B 2 23  ? 22.62400 21.71031  16.43895  1.000 89.15089  ? 23  GLY L C   1 
ATOM   1866 O O   . GLY B 2 23  ? 22.91233 20.74268  17.13598  1.000 80.06177  ? 23  GLY L O   1 
ATOM   1867 N N   . GLY B 2 24  ? 23.27718 22.02288  15.32058  1.000 108.57174 ? 24  GLY L N   1 
ATOM   1868 C CA  . GLY B 2 24  ? 24.38100 21.22801  14.81637  1.000 90.00743  ? 24  GLY L CA  1 
ATOM   1869 C C   . GLY B 2 24  ? 24.29974 21.01094  13.31873  1.000 104.08522 ? 24  GLY L C   1 
ATOM   1870 O O   . GLY B 2 24  ? 23.28338 21.33595  12.69950  1.000 129.08315 ? 24  GLY L O   1 
ATOM   1871 N N   . ASN B 2 25  ? 25.35489 20.45817  12.72015  1.000 122.72523 ? 25  ASN L N   1 
ATOM   1872 C CA  . ASN B 2 25  ? 25.34767 20.18952  11.28632  1.000 133.73213 ? 25  ASN L CA  1 
ATOM   1873 C C   . ASN B 2 25  ? 24.46477 18.98465  10.98750  1.000 130.21331 ? 25  ASN L C   1 
ATOM   1874 O O   . ASN B 2 25  ? 24.94641 17.84767  10.95256  1.000 130.83176 ? 25  ASN L O   1 
ATOM   1875 C CB  . ASN B 2 25  ? 26.77005 19.95477  10.77310  1.000 121.13863 ? 25  ASN L CB  1 
ATOM   1876 C CG  . ASN B 2 25  ? 27.75406 20.98612  11.28972  1.000 135.18364 ? 25  ASN L CG  1 
ATOM   1877 O OD1 . ASN B 2 25  ? 28.29879 20.84784  12.38541  1.000 129.15314 ? 25  ASN L OD1 1 
ATOM   1878 N ND2 . ASN B 2 25  ? 27.98723 22.02850  10.50049  1.000 140.57519 ? 25  ASN L ND2 1 
ATOM   1879 N N   . ASN B 2 26  ? 23.17124 19.22462  10.76520  1.000 123.78108 ? 26  ASN L N   1 
ATOM   1880 C CA  . ASN B 2 26  ? 22.18587 18.15331  10.67766  1.000 121.85107 ? 26  ASN L CA  1 
ATOM   1881 C C   . ASN B 2 26  ? 21.48579 18.08634  9.32567   1.000 133.69025 ? 26  ASN L C   1 
ATOM   1882 O O   . ASN B 2 26  ? 20.50696 17.34177  9.18874   1.000 139.96531 ? 26  ASN L O   1 
ATOM   1883 C CB  . ASN B 2 26  ? 21.14971 18.30475  11.79491  1.000 122.67556 ? 26  ASN L CB  1 
ATOM   1884 C CG  . ASN B 2 26  ? 21.78260 18.34492  13.17252  1.000 114.96497 ? 26  ASN L CG  1 
ATOM   1885 O OD1 . ASN B 2 26  ? 22.73760 17.61963  13.45140  1.000 110.59507 ? 26  ASN L OD1 1 
ATOM   1886 N ND2 . ASN B 2 26  ? 21.25553 19.19997  14.04094  1.000 104.52849 ? 26  ASN L ND2 1 
ATOM   1887 N N   . ILE B 2 27  ? 21.94983 18.85022  8.33326   1.000 140.51348 ? 27  ILE L N   1 
ATOM   1888 C CA  . ILE B 2 27  ? 21.46762 18.77485  6.95421   1.000 137.75009 ? 27  ILE L CA  1 
ATOM   1889 C C   . ILE B 2 27  ? 19.96324 19.05203  6.94172   1.000 123.85013 ? 27  ILE L C   1 
ATOM   1890 O O   . ILE B 2 27  ? 19.42465 19.63547  7.88932   1.000 113.85671 ? 27  ILE L O   1 
ATOM   1891 C CB  . ILE B 2 27  ? 21.83003 17.41275  6.32279   1.000 125.16472 ? 27  ILE L CB  1 
ATOM   1892 C CG1 . ILE B 2 27  ? 23.28165 17.05659  6.64877   1.000 129.64458 ? 27  ILE L CG1 1 
ATOM   1893 C CG2 . ILE B 2 27  ? 21.74827 17.45315  4.79606   1.000 122.16943 ? 27  ILE L CG2 1 
ATOM   1894 C CD1 . ILE B 2 27  ? 24.30796 17.82907  5.84159   1.000 109.75870 ? 27  ILE L CD1 1 
ATOM   1895 N N   . GLY B 2 28  ? 19.27580 18.65131  5.87386   1.000 123.64783 ? 28  GLY L N   1 
ATOM   1896 C CA  . GLY B 2 28  ? 17.87536 18.97649  5.68896   1.000 122.14809 ? 28  GLY L CA  1 
ATOM   1897 C C   . GLY B 2 28  ? 16.90487 18.19215  6.54838   1.000 113.86474 ? 28  GLY L C   1 
ATOM   1898 O O   . GLY B 2 28  ? 16.09399 18.78644  7.26354   1.000 121.41210 ? 28  GLY L O   1 
ATOM   1899 N N   . ARG B 2 29  ? 16.95247 16.86153  6.47661   1.000 115.30921 ? 29  ARG L N   1 
ATOM   1900 C CA  . ARG B 2 29  ? 16.02872 16.02455  7.23593   1.000 115.03397 ? 29  ARG L CA  1 
ATOM   1901 C C   . ARG B 2 29  ? 16.74294 15.17913  8.28159   1.000 126.66343 ? 29  ARG L C   1 
ATOM   1902 O O   . ARG B 2 29  ? 16.47146 15.33905  9.47619   1.000 114.97707 ? 29  ARG L O   1 
ATOM   1903 C CB  . ARG B 2 29  ? 15.23482 15.14337  6.26157   1.000 95.46514  ? 29  ARG L CB  1 
ATOM   1904 C CG  . ARG B 2 29  ? 14.07511 14.36940  6.86442   1.000 84.98691  ? 29  ARG L CG  1 
ATOM   1905 C CD  . ARG B 2 29  ? 14.03218 12.97210  6.27133   1.000 103.59086 ? 29  ARG L CD  1 
ATOM   1906 N NE  . ARG B 2 29  ? 12.74041 12.31781  6.43567   1.000 108.74669 ? 29  ARG L NE  1 
ATOM   1907 C CZ  . ARG B 2 29  ? 12.58277 11.04113  6.75614   1.000 89.55261  ? 29  ARG L CZ  1 
ATOM   1908 N NH1 . ARG B 2 29  ? 13.61986 10.25278  6.98547   1.000 71.79259  ? 29  ARG L NH1 1 
ATOM   1909 N NH2 . ARG B 2 29  ? 11.35384 10.54122  6.84082   1.000 77.84387  ? 29  ARG L NH2 1 
ATOM   1910 N N   . LYS B 2 30  ? 17.67324 14.31619  7.86746   1.000 131.97708 ? 30  LYS L N   1 
ATOM   1911 C CA  . LYS B 2 30  ? 18.44418 13.43428  8.75379   1.000 103.69148 ? 30  LYS L CA  1 
ATOM   1912 C C   . LYS B 2 30  ? 17.59603 12.87408  9.89468   1.000 113.49717 ? 30  LYS L C   1 
ATOM   1913 O O   . LYS B 2 30  ? 17.98480 12.89951  11.06495  1.000 124.76428 ? 30  LYS L O   1 
ATOM   1914 C CB  . LYS B 2 30  ? 19.67967 14.14898  9.29829   1.000 90.07205  ? 30  LYS L CB  1 
ATOM   1915 C CG  . LYS B 2 30  ? 20.95988 13.80454  8.55308   1.000 104.21058 ? 30  LYS L CG  1 
ATOM   1916 C CD  . LYS B 2 30  ? 22.12891 14.65011  9.02559   1.000 95.06359  ? 30  LYS L CD  1 
ATOM   1917 C CE  . LYS B 2 30  ? 22.88615 13.97540  10.15563  1.000 87.88161  ? 30  LYS L CE  1 
ATOM   1918 N NZ  . LYS B 2 30  ? 24.35300 14.21676  10.05568  1.000 85.31878  ? 30  LYS L NZ  1 
ATOM   1919 N N   . ARG B 2 31  ? 16.41320 12.36938  9.53719   1.000 110.96948 ? 31  ARG L N   1 
ATOM   1920 C CA  . ARG B 2 31  ? 15.49093 11.76416  10.49384  1.000 104.78081 ? 31  ARG L CA  1 
ATOM   1921 C C   . ARG B 2 31  ? 15.10004 12.74201  11.59718  1.000 110.58964 ? 31  ARG L C   1 
ATOM   1922 O O   . ARG B 2 31  ? 14.00082 13.30581  11.56898  1.000 117.21232 ? 31  ARG L O   1 
ATOM   1923 C CB  . ARG B 2 31  ? 16.09741 10.49490  11.10029  1.000 94.50631  ? 31  ARG L CB  1 
ATOM   1924 C CG  . ARG B 2 31  ? 15.13770 9.71109   11.97850  1.000 95.93245  ? 31  ARG L CG  1 
ATOM   1925 C CD  . ARG B 2 31  ? 13.96705 9.17228   11.17609  1.000 71.12817  ? 31  ARG L CD  1 
ATOM   1926 N NE  . ARG B 2 31  ? 13.44878 7.93042   11.73695  1.000 90.74475  ? 31  ARG L NE  1 
ATOM   1927 C CZ  . ARG B 2 31  ? 13.68602 6.72556   11.23710  1.000 93.09644  ? 31  ARG L CZ  1 
ATOM   1928 N NH1 . ARG B 2 31  ? 14.43958 6.55935   10.16267  1.000 94.81224  ? 31  ARG L NH1 1 
ATOM   1929 N NH2 . ARG B 2 31  ? 13.15500 5.66052   11.83117  1.000 90.82558  ? 31  ARG L NH2 1 
ATOM   1930 N N   . VAL B 2 32  ? 15.99829 12.94114  12.56637  1.000 105.10021 ? 32  VAL L N   1 
ATOM   1931 C CA  . VAL B 2 32  ? 15.77448 13.79102  13.73514  1.000 97.99261  ? 32  VAL L CA  1 
ATOM   1932 C C   . VAL B 2 32  ? 14.60460 13.24998  14.54757  1.000 84.67752  ? 32  VAL L C   1 
ATOM   1933 O O   . VAL B 2 32  ? 13.43633 13.49617  14.22564  1.000 87.76706  ? 32  VAL L O   1 
ATOM   1934 C CB  . VAL B 2 32  ? 15.54656 15.26289  13.34044  1.000 109.23371 ? 32  VAL L CB  1 
ATOM   1935 C CG1 . VAL B 2 32  ? 15.22603 16.09791  14.57095  1.000 77.59518  ? 32  VAL L CG1 1 
ATOM   1936 C CG2 . VAL B 2 32  ? 16.77184 15.81443  12.63264  1.000 114.23446 ? 32  VAL L CG2 1 
ATOM   1937 N N   . ASP B 2 33  ? 14.91354 12.51207  15.60866  1.000 66.08272  ? 33  ASP L N   1 
ATOM   1938 C CA  . ASP B 2 33  ? 13.91066 11.89801  16.46450  1.000 77.93392  ? 33  ASP L CA  1 
ATOM   1939 C C   . ASP B 2 33  ? 13.92165 12.56210  17.83454  1.000 77.71461  ? 33  ASP L C   1 
ATOM   1940 O O   . ASP B 2 33  ? 14.98776 12.82481  18.40079  1.000 61.94590  ? 33  ASP L O   1 
ATOM   1941 C CB  . ASP B 2 33  ? 14.16067 10.39411  16.60554  1.000 89.35663  ? 33  ASP L CB  1 
ATOM   1942 C CG  . ASP B 2 33  ? 13.86991 9.63415   15.32629  1.000 78.73877  ? 33  ASP L CG  1 
ATOM   1943 O OD1 . ASP B 2 33  ? 13.07171 10.13425  14.50717  1.000 87.43659  ? 33  ASP L OD1 1 
ATOM   1944 O OD2 . ASP B 2 33  ? 14.44182 8.54015   15.13675  1.000 84.14030  ? 33  ASP L OD2 1 
ATOM   1945 N N   . TRP B 2 34  ? 12.73153 12.83273  18.36131  1.000 72.19653  ? 34  TRP L N   1 
ATOM   1946 C CA  . TRP B 2 34  ? 12.57027 13.47409  19.65694  1.000 67.62604  ? 34  TRP L CA  1 
ATOM   1947 C C   . TRP B 2 34  ? 12.02748 12.47457  20.66796  1.000 84.46123  ? 34  TRP L C   1 
ATOM   1948 O O   . TRP B 2 34  ? 11.19219 11.62832  20.33367  1.000 81.21872  ? 34  TRP L O   1 
ATOM   1949 C CB  . TRP B 2 34  ? 11.63494 14.68133  19.56201  1.000 71.46780  ? 34  TRP L CB  1 
ATOM   1950 C CG  . TRP B 2 34  ? 12.21955 15.82270  18.79295  1.000 79.93235  ? 34  TRP L CG  1 
ATOM   1951 C CD1 . TRP B 2 34  ? 12.11818 16.04387  17.45093  1.000 79.70199  ? 34  TRP L CD1 1 
ATOM   1952 C CD2 . TRP B 2 34  ? 13.00570 16.89840  19.31889  1.000 79.77835  ? 34  TRP L CD2 1 
ATOM   1953 N NE1 . TRP B 2 34  ? 12.78879 17.19268  17.10867  1.000 92.05303  ? 34  TRP L NE1 1 
ATOM   1954 C CE2 . TRP B 2 34  ? 13.34315 17.73591  18.23766  1.000 74.67706  ? 34  TRP L CE2 1 
ATOM   1955 C CE3 . TRP B 2 34  ? 13.45567 17.23526  20.59921  1.000 80.32964  ? 34  TRP L CE3 1 
ATOM   1956 C CZ2 . TRP B 2 34  ? 14.10861 18.88879  18.39712  1.000 78.61067  ? 34  TRP L CZ2 1 
ATOM   1957 C CZ3 . TRP B 2 34  ? 14.21586 18.38024  20.75546  1.000 77.95709  ? 34  TRP L CZ3 1 
ATOM   1958 C CH2 . TRP B 2 34  ? 14.53445 19.19293  19.66066  1.000 88.12097  ? 34  TRP L CH2 1 
ATOM   1959 N N   . PHE B 2 35  ? 12.50713 12.57927  21.90491  1.000 88.23318  ? 35  PHE L N   1 
ATOM   1960 C CA  . PHE B 2 35  ? 12.10333 11.69059  22.98231  1.000 67.67939  ? 35  PHE L CA  1 
ATOM   1961 C C   . PHE B 2 35  ? 11.62143 12.50827  24.16971  1.000 70.68233  ? 35  PHE L C   1 
ATOM   1962 O O   . PHE B 2 35  ? 12.04349 13.64961  24.37221  1.000 75.13658  ? 35  PHE L O   1 
ATOM   1963 C CB  . PHE B 2 35  ? 13.25193 10.77338  23.41555  1.000 63.99966  ? 35  PHE L CB  1 
ATOM   1964 C CG  . PHE B 2 35  ? 13.64182 9.76601   22.37821  1.000 78.07158  ? 35  PHE L CG  1 
ATOM   1965 C CD1 . PHE B 2 35  ? 14.56114 10.08723  21.39494  1.000 79.10052  ? 35  PHE L CD1 1 
ATOM   1966 C CD2 . PHE B 2 35  ? 13.09104 8.49586   22.38704  1.000 75.98740  ? 35  PHE L CD2 1 
ATOM   1967 C CE1 . PHE B 2 35  ? 14.92023 9.16382   20.43663  1.000 71.28386  ? 35  PHE L CE1 1 
ATOM   1968 C CE2 . PHE B 2 35  ? 13.44862 7.56515   21.43174  1.000 89.33584  ? 35  PHE L CE2 1 
ATOM   1969 C CZ  . PHE B 2 35  ? 14.36521 7.89976   20.45496  1.000 96.43542  ? 35  PHE L CZ  1 
ATOM   1970 N N   . GLN B 2 36  ? 10.72706 11.90978  24.95095  1.000 78.16230  ? 36  GLN L N   1 
ATOM   1971 C CA  . GLN B 2 36  ? 10.16993 12.53132  26.14334  1.000 73.60842  ? 36  GLN L CA  1 
ATOM   1972 C C   . GLN B 2 36  ? 10.52873 11.68501  27.35505  1.000 81.89300  ? 36  GLN L C   1 
ATOM   1973 O O   . GLN B 2 36  ? 10.27206 10.47663  27.36926  1.000 87.03506  ? 36  GLN L O   1 
ATOM   1974 C CB  . GLN B 2 36  ? 8.65098  12.67873  26.02372  1.000 65.64366  ? 36  GLN L CB  1 
ATOM   1975 C CG  . GLN B 2 36  ? 8.01329  13.50102  27.12696  1.000 73.96478  ? 36  GLN L CG  1 
ATOM   1976 C CD  . GLN B 2 36  ? 6.54259  13.18527  27.30838  1.000 74.41839  ? 36  GLN L CD  1 
ATOM   1977 O OE1 . GLN B 2 36  ? 6.17347  12.05422  27.62495  1.000 76.25472  ? 36  GLN L OE1 1 
ATOM   1978 N NE2 . GLN B 2 36  ? 5.69266  14.18534  27.10381  1.000 60.08980  ? 36  GLN L NE2 1 
ATOM   1979 N N   . GLN B 2 37  ? 11.12304 12.31714  28.36583  1.000 90.16506  ? 37  GLN L N   1 
ATOM   1980 C CA  . GLN B 2 37  ? 11.51719 11.63652  29.59629  1.000 79.46998  ? 37  GLN L CA  1 
ATOM   1981 C C   . GLN B 2 37  ? 10.89909 12.36189  30.78261  1.000 72.71401  ? 37  GLN L C   1 
ATOM   1982 O O   . GLN B 2 37  ? 11.34466 13.45505  31.14742  1.000 76.63041  ? 37  GLN L O   1 
ATOM   1983 C CB  . GLN B 2 37  ? 13.03846 11.57427  29.73997  1.000 72.55263  ? 37  GLN L CB  1 
ATOM   1984 C CG  . GLN B 2 37  ? 13.49834 10.82073  30.98044  1.000 59.12397  ? 37  GLN L CG  1 
ATOM   1985 C CD  . GLN B 2 37  ? 14.91435 10.29478  30.86213  1.000 66.73148  ? 37  GLN L CD  1 
ATOM   1986 O OE1 . GLN B 2 37  ? 15.80225 10.97619  30.35020  1.000 71.15331  ? 37  GLN L OE1 1 
ATOM   1987 N NE2 . GLN B 2 37  ? 15.13377 9.07598   31.34219  1.000 65.97201  ? 37  GLN L NE2 1 
ATOM   1988 N N   . LYS B 2 38  ? 9.87768  11.75741  31.37813  1.000 75.64510  ? 38  LYS L N   1 
ATOM   1989 C CA  . LYS B 2 38  ? 9.33057  12.24499  32.63065  1.000 74.61533  ? 38  LYS L CA  1 
ATOM   1990 C C   . LYS B 2 38  ? 10.19571 11.76869  33.79369  1.000 74.94623  ? 38  LYS L C   1 
ATOM   1991 O O   . LYS B 2 38  ? 10.90952 10.76915  33.67638  1.000 73.07512  ? 38  LYS L O   1 
ATOM   1992 C CB  . LYS B 2 38  ? 7.89230  11.76453  32.79614  1.000 72.67125  ? 38  LYS L CB  1 
ATOM   1993 C CG  . LYS B 2 38  ? 6.88917  12.52557  31.94118  1.000 64.18108  ? 38  LYS L CG  1 
ATOM   1994 C CD  . LYS B 2 38  ? 5.69672  11.65736  31.57657  1.000 92.30785  ? 38  LYS L CD  1 
ATOM   1995 C CE  . LYS B 2 38  ? 6.09832  10.54605  30.61883  1.000 107.23684 ? 38  LYS L CE  1 
ATOM   1996 N NZ  . LYS B 2 38  ? 5.00475  10.20113  29.66810  1.000 79.21500  ? 38  LYS L NZ  1 
ATOM   1997 N N   . PRO B 2 39  ? 10.17352 12.48458  34.91869  1.000 83.61586  ? 39  PRO L N   1 
ATOM   1998 C CA  . PRO B 2 39  ? 11.00059 12.08249  36.06497  1.000 73.78064  ? 39  PRO L CA  1 
ATOM   1999 C C   . PRO B 2 39  ? 10.72431 10.64540  36.48487  1.000 69.18046  ? 39  PRO L C   1 
ATOM   2000 O O   . PRO B 2 39  ? 9.57160  10.22549  36.60886  1.000 70.84765  ? 39  PRO L O   1 
ATOM   2001 C CB  . PRO B 2 39  ? 10.59037 13.07653  37.15466  1.000 51.84297  ? 39  PRO L CB  1 
ATOM   2002 C CG  . PRO B 2 39  ? 10.21638 14.30394  36.39988  1.000 91.31525  ? 39  PRO L CG  1 
ATOM   2003 C CD  . PRO B 2 39  ? 9.61325  13.83754  35.09267  1.000 89.00471  ? 39  PRO L CD  1 
ATOM   2004 N N   . GLY B 2 40  ? 11.79935 9.89505   36.70674  1.000 63.39774  ? 40  GLY L N   1 
ATOM   2005 C CA  . GLY B 2 40  ? 11.67858 8.49956   37.10063  1.000 63.25635  ? 40  GLY L CA  1 
ATOM   2006 C C   . GLY B 2 40  ? 10.97494 7.62768   36.08366  1.000 73.99621  ? 40  GLY L C   1 
ATOM   2007 O O   . GLY B 2 40  ? 10.17653 6.76028   36.45965  1.000 91.39962  ? 40  GLY L O   1 
ATOM   2008 N N   . GLN B 2 41  ? 11.25483 7.83353   34.79868  1.000 74.97846  ? 41  GLN L N   1 
ATOM   2009 C CA  . GLN B 2 41  ? 10.59909 7.07080   33.74767  1.000 73.97668  ? 41  GLN L CA  1 
ATOM   2010 C C   . GLN B 2 41  ? 11.54487 6.92056   32.56553  1.000 89.13112  ? 41  GLN L C   1 
ATOM   2011 O O   . GLN B 2 41  ? 12.43510 7.74858   32.35327  1.000 81.07980  ? 41  GLN L O   1 
ATOM   2012 C CB  . GLN B 2 41  ? 9.29449  7.74096   33.29960  1.000 87.37881  ? 41  GLN L CB  1 
ATOM   2013 C CG  . GLN B 2 41  ? 8.03787  7.12014   33.88793  1.000 87.90044  ? 41  GLN L CG  1 
ATOM   2014 C CD  . GLN B 2 41  ? 6.76905  7.73273   33.32562  1.000 99.71320  ? 41  GLN L CD  1 
ATOM   2015 O OE1 . GLN B 2 41  ? 6.44642  7.55292   32.15107  1.000 101.69275 ? 41  GLN L OE1 1 
ATOM   2016 N NE2 . GLN B 2 41  ? 6.04217  8.46244   34.16401  1.000 106.63742 ? 41  GLN L NE2 1 
ATOM   2017 N N   . ALA B 2 42  ? 11.34149 5.85201   31.79931  1.000 85.22035  ? 42  ALA L N   1 
ATOM   2018 C CA  . ALA B 2 42  ? 12.13697 5.63163   30.60500  1.000 75.11268  ? 42  ALA L CA  1 
ATOM   2019 C C   . ALA B 2 42  ? 11.72354 6.60867   29.50504  1.000 87.91103  ? 42  ALA L C   1 
ATOM   2020 O O   . ALA B 2 42  ? 10.56149 7.01811   29.43187  1.000 84.45867  ? 42  ALA L O   1 
ATOM   2021 C CB  . ALA B 2 42  ? 11.97845 4.19677   30.11151  1.000 69.34799  ? 42  ALA L CB  1 
ATOM   2022 N N   . PRO B 2 43  ? 12.66202 7.00968   28.64702  1.000 87.92552  ? 43  PRO L N   1 
ATOM   2023 C CA  . PRO B 2 43  ? 12.31128 7.90307   27.53786  1.000 70.96261  ? 43  PRO L CA  1 
ATOM   2024 C C   . PRO B 2 43  ? 11.30287 7.25857   26.59843  1.000 73.85362  ? 43  PRO L C   1 
ATOM   2025 O O   . PRO B 2 43  ? 11.31440 6.04677   26.37205  1.000 74.34917  ? 43  PRO L O   1 
ATOM   2026 C CB  . PRO B 2 43  ? 13.65434 8.13964   26.83795  1.000 77.02864  ? 43  PRO L CB  1 
ATOM   2027 C CG  . PRO B 2 43  ? 14.67121 7.91960   27.91028  1.000 65.58988  ? 43  PRO L CG  1 
ATOM   2028 C CD  . PRO B 2 43  ? 14.11618 6.79197   28.73532  1.000 81.64608  ? 43  PRO L CD  1 
ATOM   2029 N N   . VAL B 2 44  ? 10.41927 8.08938   26.05138  1.000 75.01888  ? 44  VAL L N   1 
ATOM   2030 C CA  . VAL B 2 44  ? 9.40546  7.64967   25.10161  1.000 82.14133  ? 44  VAL L CA  1 
ATOM   2031 C C   . VAL B 2 44  ? 9.48829  8.52547   23.85764  1.000 90.80361  ? 44  VAL L C   1 
ATOM   2032 O O   . VAL B 2 44  ? 9.67836  9.74345   23.95171  1.000 91.52961  ? 44  VAL L O   1 
ATOM   2033 C CB  . VAL B 2 44  ? 7.98814  7.67894   25.71953  1.000 66.15513  ? 44  VAL L CB  1 
ATOM   2034 C CG1 . VAL B 2 44  ? 7.55477  9.10201   26.04594  1.000 69.54130  ? 44  VAL L CG1 1 
ATOM   2035 C CG2 . VAL B 2 44  ? 6.98628  7.01015   24.78922  1.000 95.12835  ? 44  VAL L CG2 1 
ATOM   2036 N N   . LEU B 2 45  ? 9.38067  7.89611   22.68984  1.000 92.17385  ? 45  LEU L N   1 
ATOM   2037 C CA  . LEU B 2 45  ? 9.44839  8.61342   21.42390  1.000 95.21559  ? 45  LEU L CA  1 
ATOM   2038 C C   . LEU B 2 45  ? 8.13365  9.34137   21.16849  1.000 89.62679  ? 45  LEU L C   1 
ATOM   2039 O O   . LEU B 2 45  ? 7.05430  8.75941   21.31637  1.000 98.74362  ? 45  LEU L O   1 
ATOM   2040 C CB  . LEU B 2 45  ? 9.75503  7.64080   20.28515  1.000 90.44812  ? 45  LEU L CB  1 
ATOM   2041 C CG  . LEU B 2 45  ? 9.61928  8.15037   18.85083  1.000 71.09918  ? 45  LEU L CG  1 
ATOM   2042 C CD1 . LEU B 2 45  ? 10.84386 8.96065   18.46292  1.000 78.44370  ? 45  LEU L CD1 1 
ATOM   2043 C CD2 . LEU B 2 45  ? 9.41257  6.99063   17.89006  1.000 75.88167  ? 45  LEU L CD2 1 
ATOM   2044 N N   . VAL B 2 46  ? 8.22339  10.61308  20.78575  1.000 86.88300  ? 46  VAL L N   1 
ATOM   2045 C CA  . VAL B 2 46  ? 7.05590  11.46375  20.58438  1.000 99.30488  ? 46  VAL L CA  1 
ATOM   2046 C C   . VAL B 2 46  ? 6.82299  11.75881  19.10527  1.000 98.20084  ? 46  VAL L C   1 
ATOM   2047 O O   . VAL B 2 46  ? 5.69332  11.68381  18.62145  1.000 90.63297  ? 46  VAL L O   1 
ATOM   2048 C CB  . VAL B 2 46  ? 7.17426  12.77141  21.39930  1.000 87.10027  ? 46  VAL L CB  1 
ATOM   2049 C CG1 . VAL B 2 46  ? 6.74886  12.53450  22.83890  1.000 72.52157  ? 46  VAL L CG1 1 
ATOM   2050 C CG2 . VAL B 2 46  ? 8.59307  13.31253  21.34119  1.000 84.44357  ? 46  VAL L CG2 1 
ATOM   2051 N N   . VAL B 2 47  ? 7.87958  12.11598  18.37504  1.000 94.20059  ? 47  VAL L N   1 
ATOM   2052 C CA  . VAL B 2 47  ? 7.78991  12.37576  16.94280  1.000 95.49154  ? 47  VAL L CA  1 
ATOM   2053 C C   . VAL B 2 47  ? 8.99713  11.75491  16.25406  1.000 99.08343  ? 47  VAL L C   1 
ATOM   2054 O O   . VAL B 2 47  ? 10.09228 11.68245  16.81992  1.000 97.59089  ? 47  VAL L O   1 
ATOM   2055 C CB  . VAL B 2 47  ? 7.69946  13.88709  16.61410  1.000 88.38349  ? 47  VAL L CB  1 
ATOM   2056 C CG1 . VAL B 2 47  ? 6.44241  14.50188  17.21233  1.000 106.75459 ? 47  VAL L CG1 1 
ATOM   2057 C CG2 . VAL B 2 47  ? 8.93601  14.61945  17.10545  1.000 90.85191  ? 47  VAL L CG2 1 
ATOM   2058 N N   . TYR B 2 48  ? 8.78668  11.29675  15.02171  1.000 104.70079 ? 48  TYR L N   1 
ATOM   2059 C CA  . TYR B 2 48  ? 9.85486  10.72295  14.21789  1.000 105.57135 ? 48  TYR L CA  1 
ATOM   2060 C C   . TYR B 2 48  ? 9.65963  11.12019  12.76231  1.000 106.31112 ? 48  TYR L C   1 
ATOM   2061 O O   . TYR B 2 48  ? 8.55442  11.46135  12.33477  1.000 102.26457 ? 48  TYR L O   1 
ATOM   2062 C CB  . TYR B 2 48  ? 9.91283  9.19331   14.34982  1.000 99.70340  ? 48  TYR L CB  1 
ATOM   2063 C CG  . TYR B 2 48  ? 8.67949  8.46547   13.85520  1.000 106.96748 ? 48  TYR L CG  1 
ATOM   2064 C CD1 . TYR B 2 48  ? 8.57011  8.06228   12.52966  1.000 117.82170 ? 48  TYR L CD1 1 
ATOM   2065 C CD2 . TYR B 2 48  ? 7.63946  8.15361   14.72047  1.000 103.18397 ? 48  TYR L CD2 1 
ATOM   2066 C CE1 . TYR B 2 48  ? 7.45060  7.39085   12.07521  1.000 124.72128 ? 48  TYR L CE1 1 
ATOM   2067 C CE2 . TYR B 2 48  ? 6.51676  7.47783   14.27542  1.000 105.09989 ? 48  TYR L CE2 1 
ATOM   2068 C CZ  . TYR B 2 48  ? 6.42743  7.10107   12.95210  1.000 121.64750 ? 48  TYR L CZ  1 
ATOM   2069 O OH  . TYR B 2 48  ? 5.31236  6.43051   12.50405  1.000 136.67856 ? 48  TYR L OH  1 
ATOM   2070 N N   . GLU B 2 49  ? 10.75624 11.06211  12.00309  1.000 106.02541 ? 49  GLU L N   1 
ATOM   2071 C CA  . GLU B 2 49  ? 10.75320 11.40541  10.58464  1.000 108.94928 ? 49  GLU L CA  1 
ATOM   2072 C C   . GLU B 2 49  ? 10.17579 12.79876  10.36245  1.000 105.61062 ? 49  GLU L C   1 
ATOM   2073 O O   . GLU B 2 49  ? 10.71601 13.78925  10.86607  1.000 108.88219 ? 49  GLU L O   1 
ATOM   2074 C CB  . GLU B 2 49  ? 9.96759  10.36239  9.78389   1.000 112.35295 ? 49  GLU L CB  1 
ATOM   2075 C CG  . GLU B 2 49  ? 10.68049 9.02558   9.63459   1.000 112.82003 ? 49  GLU L CG  1 
ATOM   2076 C CD  . GLU B 2 49  ? 9.72536  7.87998   9.36083   1.000 115.82990 ? 49  GLU L CD  1 
ATOM   2077 O OE1 . GLU B 2 49  ? 8.58116  8.14690   8.93694   1.000 109.31912 ? 49  GLU L OE1 1 
ATOM   2078 O OE2 . GLU B 2 49  ? 10.11804 6.71267   9.57164   1.000 107.79530 ? 49  GLU L OE2 1 
ATOM   2079 N N   . ASP B 2 50  ? 9.08365  12.88463  9.60626   1.000 112.09441 ? 50  ASP L N   1 
ATOM   2080 C CA  . ASP B 2 50  ? 8.35065  14.13121  9.41323   1.000 110.44442 ? 50  ASP L CA  1 
ATOM   2081 C C   . ASP B 2 50  ? 7.08341  14.07510  10.26239  1.000 102.38598 ? 50  ASP L C   1 
ATOM   2082 O O   . ASP B 2 50  ? 6.12808  13.37073  9.91830   1.000 119.04160 ? 50  ASP L O   1 
ATOM   2083 C CB  . ASP B 2 50  ? 8.03427  14.35534  7.93424   1.000 106.20323 ? 50  ASP L CB  1 
ATOM   2084 C CG  . ASP B 2 50  ? 7.37424  13.15134  7.28312   1.000 114.10431 ? 50  ASP L CG  1 
ATOM   2085 O OD1 . ASP B 2 50  ? 7.81804  12.01241  7.54448   1.000 111.82694 ? 50  ASP L OD1 1 
ATOM   2086 O OD2 . ASP B 2 50  ? 6.41076  13.34486  6.51124   1.000 116.32170 ? 50  ASP L OD2 1 
ATOM   2087 N N   . SER B 2 51  ? 7.08475  14.81570  11.37442  1.000 89.78943  ? 51  SER L N   1 
ATOM   2088 C CA  . SER B 2 51  ? 6.00073  14.78681  12.35278  1.000 109.03586 ? 51  SER L CA  1 
ATOM   2089 C C   . SER B 2 51  ? 5.77501  13.36316  12.85232  1.000 120.87492 ? 51  SER L C   1 
ATOM   2090 O O   . SER B 2 51  ? 6.54945  12.86194  13.67438  1.000 127.94757 ? 51  SER L O   1 
ATOM   2091 C CB  . SER B 2 51  ? 4.71580  15.36798  11.75615  1.000 93.95397  ? 51  SER L CB  1 
ATOM   2092 O OG  . SER B 2 51  ? 4.74676  16.78501  11.76648  1.000 88.13728  ? 51  SER L OG  1 
ATOM   2093 N N   . ASP B 2 52  ? 4.71690  12.70963  12.36596  1.000 104.90803 ? 52  ASP L N   1 
ATOM   2094 C CA  . ASP B 2 52  ? 4.49613  11.27375  12.55725  1.000 118.72302 ? 52  ASP L CA  1 
ATOM   2095 C C   . ASP B 2 52  ? 4.43342  10.90367  14.04446  1.000 122.91565 ? 52  ASP L C   1 
ATOM   2096 O O   . ASP B 2 52  ? 5.31277  10.23981  14.59326  1.000 115.11794 ? 52  ASP L O   1 
ATOM   2097 C CB  . ASP B 2 52  ? 5.57556  10.45869  11.83463  1.000 114.01268 ? 52  ASP L CB  1 
ATOM   2098 C CG  . ASP B 2 52  ? 5.36007  10.40476  10.33575  1.000 136.40884 ? 52  ASP L CG  1 
ATOM   2099 O OD1 . ASP B 2 52  ? 4.19187  10.30886  9.90399   1.000 149.11977 ? 52  ASP L OD1 1 
ATOM   2100 O OD2 . ASP B 2 52  ? 6.36001  10.45756  9.58888   1.000 136.95516 ? 52  ASP L OD2 1 
ATOM   2101 N N   . ARG B 2 53  ? 3.37641  11.37348  14.68858  1.000 116.05292 ? 53  ARG L N   1 
ATOM   2102 C CA  . ARG B 2 53  ? 3.11748  10.99169  16.07541  1.000 102.23900 ? 53  ARG L CA  1 
ATOM   2103 C C   . ARG B 2 53  ? 2.71172  9.52262   16.13679  1.000 115.37211 ? 53  ARG L C   1 
ATOM   2104 O O   . ARG B 2 53  ? 1.68578  9.14884   15.55241  1.000 122.03796 ? 53  ARG L O   1 
ATOM   2105 C CB  . ARG B 2 53  ? 2.02783  11.87884  16.65286  1.000 104.03982 ? 53  ARG L CB  1 
ATOM   2106 C CG  . ARG B 2 53  ? 2.33314  13.35787  16.51817  1.000 103.45745 ? 53  ARG L CG  1 
ATOM   2107 C CD  . ARG B 2 53  ? 1.09394  14.13867  16.13273  1.000 89.41418  ? 53  ARG L CD  1 
ATOM   2108 N NE  . ARG B 2 53  ? 0.80500  14.04401  14.70676  1.000 106.76867 ? 53  ARG L NE  1 
ATOM   2109 C CZ  . ARG B 2 53  ? 1.41105  14.76096  13.76998  1.000 117.86008 ? 53  ARG L CZ  1 
ATOM   2110 N NH1 . ARG B 2 53  ? 2.34202  15.65049  14.07426  1.000 121.80613 ? 53  ARG L NH1 1 
ATOM   2111 N NH2 . ARG B 2 53  ? 1.07411  14.58143  12.49579  1.000 99.32889  ? 53  ARG L NH2 1 
ATOM   2112 N N   . PRO B 2 54  ? 3.47303  8.65908   16.82734  1.000 111.71074 ? 54  PRO L N   1 
ATOM   2113 C CA  . PRO B 2 54  ? 3.28810  7.20890   16.66426  1.000 112.36365 ? 54  PRO L CA  1 
ATOM   2114 C C   . PRO B 2 54  ? 1.98060  6.62692   17.18800  1.000 122.04956 ? 54  PRO L C   1 
ATOM   2115 O O   . PRO B 2 54  ? 1.22852  6.01697   16.42217  1.000 138.62904 ? 54  PRO L O   1 
ATOM   2116 C CB  . PRO B 2 54  ? 4.48987  6.62253   17.42650  1.000 101.11106 ? 54  PRO L CB  1 
ATOM   2117 C CG  . PRO B 2 54  ? 5.31325  7.82337   17.89857  1.000 86.24082  ? 54  PRO L CG  1 
ATOM   2118 C CD  . PRO B 2 54  ? 4.34939  8.94937   17.96813  1.000 96.76606  ? 54  PRO L CD  1 
ATOM   2119 N N   . SER B 2 55  ? 1.69255  6.79591   18.47916  1.000 103.73755 ? 55  SER L N   1 
ATOM   2120 C CA  . SER B 2 55  ? 0.63216  6.02186   19.11953  1.000 117.70172 ? 55  SER L CA  1 
ATOM   2121 C C   . SER B 2 55  ? -0.47422 6.89261   19.69780  1.000 123.15738 ? 55  SER L C   1 
ATOM   2122 O O   . SER B 2 55  ? -1.63034 6.76904   19.28014  1.000 126.53552 ? 55  SER L O   1 
ATOM   2123 C CB  . SER B 2 55  ? 1.24342  5.12996   20.21016  1.000 127.70674 ? 55  SER L CB  1 
ATOM   2124 O OG  . SER B 2 55  ? 0.29659  4.20811   20.72284  1.000 147.45506 ? 55  SER L OG  1 
ATOM   2125 N N   . GLY B 2 56  ? -0.15611 7.77315   20.64166  1.000 119.09493 ? 56  GLY L N   1 
ATOM   2126 C CA  . GLY B 2 56  ? -1.15962 8.59912   21.28116  1.000 103.39999 ? 56  GLY L CA  1 
ATOM   2127 C C   . GLY B 2 56  ? -0.65834 10.00670  21.51332  1.000 103.59544 ? 56  GLY L C   1 
ATOM   2128 O O   . GLY B 2 56  ? -1.30919 10.80674  22.19299  1.000 90.97965  ? 56  GLY L O   1 
ATOM   2129 N N   . ILE B 2 57  ? 0.50557  10.31444  20.94959  1.000 97.78826  ? 57  ILE L N   1 
ATOM   2130 C CA  . ILE B 2 57  ? 1.06127  11.66370  21.08676  1.000 108.81676 ? 57  ILE L CA  1 
ATOM   2131 C C   . ILE B 2 57  ? 0.12448  12.65564  20.40926  1.000 100.31099 ? 57  ILE L C   1 
ATOM   2132 O O   . ILE B 2 57  ? -0.26195 12.44427  19.24240  1.000 95.43549  ? 57  ILE L O   1 
ATOM   2133 C CB  . ILE B 2 57  ? 2.47248  11.73153  20.47759  1.000 104.74099 ? 57  ILE L CB  1 
ATOM   2134 C CG1 . ILE B 2 57  ? 3.46045  10.91696  21.31823  1.000 99.95054  ? 57  ILE L CG1 1 
ATOM   2135 C CG2 . ILE B 2 57  ? 2.93528  13.17735  20.35497  1.000 100.08514 ? 57  ILE L CG2 1 
ATOM   2136 C CD1 . ILE B 2 57  ? 3.29465  11.09315  22.81574  1.000 93.03949  ? 57  ILE L CD1 1 
ATOM   2137 N N   . PRO B 2 58  ? -0.27741 13.73484  21.07935  1.000 112.22396 ? 58  PRO L N   1 
ATOM   2138 C CA  . PRO B 2 58  ? -1.26188 14.64807  20.49095  1.000 97.33262  ? 58  PRO L CA  1 
ATOM   2139 C C   . PRO B 2 58  ? -0.73801 15.31046  19.22578  1.000 108.51350 ? 58  PRO L C   1 
ATOM   2140 O O   . PRO B 2 58  ? 0.46857  15.43851  19.00676  1.000 106.45962 ? 58  PRO L O   1 
ATOM   2141 C CB  . PRO B 2 58  ? -1.49238 15.68024  21.60202  1.000 109.07515 ? 58  PRO L CB  1 
ATOM   2142 C CG  . PRO B 2 58  ? -1.13518 14.95047  22.86030  1.000 116.00245 ? 58  PRO L CG  1 
ATOM   2143 C CD  . PRO B 2 58  ? 0.04136  14.10129  22.46976  1.000 112.53592 ? 58  PRO L CD  1 
ATOM   2144 N N   . GLU B 2 59  ? -1.68116 15.74500  18.38616  1.000 123.09802 ? 59  GLU L N   1 
ATOM   2145 C CA  . GLU B 2 59  ? -1.34149 16.42945  17.14410  1.000 107.98386 ? 59  GLU L CA  1 
ATOM   2146 C C   . GLU B 2 59  ? -0.64868 17.76143  17.38820  1.000 102.37067 ? 59  GLU L C   1 
ATOM   2147 O O   . GLU B 2 59  ? -0.09803 18.34023  16.44488  1.000 104.95690 ? 59  GLU L O   1 
ATOM   2148 C CB  . GLU B 2 59  ? -2.60216 16.63536  16.30259  1.000 114.19503 ? 59  GLU L CB  1 
ATOM   2149 C CG  . GLU B 2 59  ? -3.82230 17.04712  17.10918  1.000 124.68507 ? 59  GLU L CG  1 
ATOM   2150 C CD  . GLU B 2 59  ? -5.11743 16.84836  16.34743  1.000 140.01768 ? 59  GLU L CD  1 
ATOM   2151 O OE1 . GLU B 2 59  ? -5.06058 16.39758  15.18391  1.000 131.61870 ? 59  GLU L OE1 1 
ATOM   2152 O OE2 . GLU B 2 59  ? -6.19228 17.13988  16.91308  1.000 151.58066 ? 59  GLU L OE2 1 
ATOM   2153 N N   . ARG B 2 60  ? -0.66780 18.25541  18.62704  1.000 105.96379 ? 60  ARG L N   1 
ATOM   2154 C CA  . ARG B 2 60  ? 0.03669  19.47974  18.98229  1.000 102.31088 ? 60  ARG L CA  1 
ATOM   2155 C C   . ARG B 2 60  ? 1.54695  19.35456  18.81595  1.000 92.21612  ? 60  ARG L C   1 
ATOM   2156 O O   . ARG B 2 60  ? 2.23891  20.37681  18.75716  1.000 83.37794  ? 60  ARG L O   1 
ATOM   2157 C CB  . ARG B 2 60  ? -0.30793 19.85008  20.42392  1.000 91.78123  ? 60  ARG L CB  1 
ATOM   2158 C CG  . ARG B 2 60  ? -1.70735 19.40787  20.83535  1.000 103.62694 ? 60  ARG L CG  1 
ATOM   2159 C CD  . ARG B 2 60  ? -2.04086 19.80356  22.26421  1.000 99.00704  ? 60  ARG L CD  1 
ATOM   2160 N NE  . ARG B 2 60  ? -1.73521 18.73759  23.21090  1.000 110.59074 ? 60  ARG L NE  1 
ATOM   2161 C CZ  . ARG B 2 60  ? -0.71493 18.75585  24.05752  1.000 107.66013 ? 60  ARG L CZ  1 
ATOM   2162 N NH1 . ARG B 2 60  ? 0.12536  19.77663  24.10540  1.000 106.61336 ? 60  ARG L NH1 1 
ATOM   2163 N NH2 . ARG B 2 60  ? -0.53363 17.72430  24.87741  1.000 88.70426  ? 60  ARG L NH2 1 
ATOM   2164 N N   . PHE B 2 61  ? 2.07238  18.13359  18.73965  1.000 91.52766  ? 61  PHE L N   1 
ATOM   2165 C CA  . PHE B 2 61  ? 3.50431  17.90868  18.58905  1.000 84.21335  ? 61  PHE L CA  1 
ATOM   2166 C C   . PHE B 2 61  ? 3.87047  17.87581  17.11012  1.000 88.06252  ? 61  PHE L C   1 
ATOM   2167 O O   . PHE B 2 61  ? 3.23152  17.17241  16.32088  1.000 92.07482  ? 61  PHE L O   1 
ATOM   2168 C CB  . PHE B 2 61  ? 3.92606  16.60014  19.26217  1.000 84.17374  ? 61  PHE L CB  1 
ATOM   2169 C CG  . PHE B 2 61  ? 3.89815  16.64552  20.76716  1.000 96.91321  ? 61  PHE L CG  1 
ATOM   2170 C CD1 . PHE B 2 61  ? 2.70955  16.84282  21.45288  1.000 103.56545 ? 61  PHE L CD1 1 
ATOM   2171 C CD2 . PHE B 2 61  ? 5.06495  16.48524  21.49615  1.000 97.02091  ? 61  PHE L CD2 1 
ATOM   2172 C CE1 . PHE B 2 61  ? 2.68635  16.88159  22.83505  1.000 89.19434  ? 61  PHE L CE1 1 
ATOM   2173 C CE2 . PHE B 2 61  ? 5.04772  16.52299  22.87844  1.000 92.58169  ? 61  PHE L CE2 1 
ATOM   2174 C CZ  . PHE B 2 61  ? 3.85675  16.72160  23.54806  1.000 78.57065  ? 61  PHE L CZ  1 
ATOM   2175 N N   . SER B 2 62  ? 4.90042  18.63448  16.74076  1.000 79.29146  ? 62  SER L N   1 
ATOM   2176 C CA  . SER B 2 62  ? 5.36067  18.68836  15.36097  1.000 70.40413  ? 62  SER L CA  1 
ATOM   2177 C C   . SER B 2 62  ? 6.86843  18.88764  15.34743  1.000 83.96230  ? 62  SER L C   1 
ATOM   2178 O O   . SER B 2 62  ? 7.41713  19.58119  16.20768  1.000 89.94672  ? 62  SER L O   1 
ATOM   2179 C CB  . SER B 2 62  ? 4.66975  19.81356  14.58227  1.000 61.97024  ? 62  SER L CB  1 
ATOM   2180 O OG  . SER B 2 62  ? 4.61615  21.00479  15.34752  1.000 80.80358  ? 62  SER L OG  1 
ATOM   2181 N N   . ASP B 2 63  ? 7.53019  18.27845  14.36597  1.000 101.11606 ? 63  ASP L N   1 
ATOM   2182 C CA  . ASP B 2 63  ? 8.98087  18.35187  14.22175  1.000 88.64608  ? 63  ASP L CA  1 
ATOM   2183 C C   . ASP B 2 63  ? 9.30165  18.99494  12.87854  1.000 97.57730  ? 63  ASP L C   1 
ATOM   2184 O O   . ASP B 2 63  ? 9.02728  18.41187  11.82392  1.000 103.22800 ? 63  ASP L O   1 
ATOM   2185 C CB  . ASP B 2 63  ? 9.61191  16.96411  14.33290  1.000 90.06255  ? 63  ASP L CB  1 
ATOM   2186 C CG  . ASP B 2 63  ? 11.11401 16.98570  14.12122  1.000 104.16940 ? 63  ASP L CG  1 
ATOM   2187 O OD1 . ASP B 2 63  ? 11.74203 18.03316  14.38570  1.000 91.33338  ? 63  ASP L OD1 1 
ATOM   2188 O OD2 . ASP B 2 63  ? 11.66730 15.95233  13.68948  1.000 118.63687 ? 63  ASP L OD2 1 
ATOM   2189 N N   . SER B 2 64  ? 9.88120  20.19195  12.91915  1.000 79.87830  ? 64  SER L N   1 
ATOM   2190 C CA  . SER B 2 64  ? 10.30575 20.91309  11.72711  1.000 77.56536  ? 64  SER L CA  1 
ATOM   2191 C C   . SER B 2 64  ? 11.79651 21.19604  11.82804  1.000 72.98998  ? 64  SER L C   1 
ATOM   2192 O O   . SER B 2 64  ? 12.27467 21.64839  12.87214  1.000 98.19671  ? 64  SER L O   1 
ATOM   2193 C CB  . SER B 2 64  ? 9.52556  22.22034  11.56474  1.000 91.10043  ? 64  SER L CB  1 
ATOM   2194 O OG  . SER B 2 64  ? 10.14093 23.06711  10.60959  1.000 101.67615 ? 64  SER L OG  1 
ATOM   2195 N N   . ASN B 2 65  ? 12.53079 20.92206  10.75029  1.000 79.03894  ? 65  ASN L N   1 
ATOM   2196 C CA  . ASN B 2 65  ? 13.97384 21.13615  10.77392  1.000 93.10122  ? 65  ASN L CA  1 
ATOM   2197 C C   . ASN B 2 65  ? 14.32142 22.59127  10.47212  1.000 104.41365 ? 65  ASN L C   1 
ATOM   2198 O O   . ASN B 2 65  ? 14.84483 23.30738  11.33224  1.000 96.20758  ? 65  ASN L O   1 
ATOM   2199 C CB  . ASN B 2 65  ? 14.65328 20.19426  9.77716   1.000 83.30757  ? 65  ASN L CB  1 
ATOM   2200 C CG  . ASN B 2 65  ? 16.16256 20.32973  9.77859   1.000 85.57017  ? 65  ASN L CG  1 
ATOM   2201 O OD1 . ASN B 2 65  ? 16.85305 19.71522  10.59207  1.000 73.05483  ? 65  ASN L OD1 1 
ATOM   2202 N ND2 . ASN B 2 65  ? 16.68376 21.13114  8.85927   1.000 88.53318  ? 65  ASN L ND2 1 
ATOM   2203 N N   . SER B 2 66  ? 13.99711 23.05462  9.26430   1.000 115.64991 ? 66  SER L N   1 
ATOM   2204 C CA  . SER B 2 66  ? 14.27486 24.42586  8.83416   1.000 130.11890 ? 66  SER L CA  1 
ATOM   2205 C C   . SER B 2 66  ? 15.77591 24.73247  8.88198   1.000 120.55120 ? 66  SER L C   1 
ATOM   2206 O O   . SER B 2 66  ? 16.24655 25.57196  9.65277   1.000 96.73592  ? 66  SER L O   1 
ATOM   2207 C CB  . SER B 2 66  ? 13.47582 25.43460  9.66986   1.000 124.22850 ? 66  SER L CB  1 
ATOM   2208 O OG  . SER B 2 66  ? 12.10272 25.43497  9.31420   1.000 123.28588 ? 66  SER L OG  1 
ATOM   2209 N N   . GLY B 2 67  ? 16.52800 24.02084  8.04277   1.000 101.68361 ? 67  GLY L N   1 
ATOM   2210 C CA  . GLY B 2 67  ? 17.93912 24.31165  7.86231   1.000 93.13270  ? 67  GLY L CA  1 
ATOM   2211 C C   . GLY B 2 67  ? 18.88359 23.42497  8.64830   1.000 104.00495 ? 67  GLY L C   1 
ATOM   2212 O O   . GLY B 2 67  ? 18.71041 22.20419  8.68681   1.000 104.50993 ? 67  GLY L O   1 
ATOM   2213 N N   . THR B 2 68  ? 19.89246 24.03112  9.28113   1.000 98.94442  ? 68  THR L N   1 
ATOM   2214 C CA  . THR B 2 68  ? 20.87616 23.30908  10.08094  1.000 100.10340 ? 68  THR L CA  1 
ATOM   2215 C C   . THR B 2 68  ? 20.50438 23.26418  11.55867  1.000 105.38239 ? 68  THR L C   1 
ATOM   2216 O O   . THR B 2 68  ? 21.38875 23.28910  12.42589  1.000 105.67028 ? 68  THR L O   1 
ATOM   2217 C CB  . THR B 2 68  ? 22.26294 23.92810  9.89969   1.000 103.27051 ? 68  THR L CB  1 
ATOM   2218 O OG1 . THR B 2 68  ? 22.19019 25.34447  10.10494  1.000 112.65364 ? 68  THR L OG1 1 
ATOM   2219 C CG2 . THR B 2 68  ? 22.79394 23.64675  8.49982   1.000 118.16625 ? 68  THR L CG2 1 
ATOM   2220 N N   . THR B 2 69  ? 19.21152 23.21644  11.86423  1.000 104.62420 ? 69  THR L N   1 
ATOM   2221 C CA  . THR B 2 69  ? 18.71733 23.20376  13.23045  1.000 102.10322 ? 69  THR L CA  1 
ATOM   2222 C C   . THR B 2 69  ? 17.53655 22.24348  13.29382  1.000 90.94211  ? 69  THR L C   1 
ATOM   2223 O O   . THR B 2 69  ? 16.87270 21.99722  12.28603  1.000 106.97744 ? 69  THR L O   1 
ATOM   2224 C CB  . THR B 2 69  ? 18.32591 24.62981  13.67060  1.000 95.14547  ? 69  THR L CB  1 
ATOM   2225 O OG1 . THR B 2 69  ? 19.51018 25.42482  13.81297  1.000 76.19645  ? 69  THR L OG1 1 
ATOM   2226 C CG2 . THR B 2 69  ? 17.58430 24.62843  14.99216  1.000 96.31468  ? 69  THR L CG2 1 
ATOM   2227 N N   . ALA B 2 70  ? 17.30346 21.66640  14.46855  1.000 79.40410  ? 70  ALA L N   1 
ATOM   2228 C CA  . ALA B 2 70  ? 16.14175 20.82241  14.71087  1.000 77.52048  ? 70  ALA L CA  1 
ATOM   2229 C C   . ALA B 2 70  ? 15.21186 21.52422  15.69087  1.000 81.56126  ? 70  ALA L C   1 
ATOM   2230 O O   . ALA B 2 70  ? 15.66004 22.02453  16.72800  1.000 95.59196  ? 70  ALA L O   1 
ATOM   2231 C CB  . ALA B 2 70  ? 16.55814 19.45397  15.25169  1.000 91.32857  ? 70  ALA L CB  1 
ATOM   2232 N N   . THR B 2 71  ? 13.92254 21.56266  15.36047  1.000 72.51557  ? 71  THR L N   1 
ATOM   2233 C CA  . THR B 2 71  ? 12.93249 22.27825  16.15451  1.000 71.00482  ? 71  THR L CA  1 
ATOM   2234 C C   . THR B 2 71  ? 11.77687 21.35013  16.49773  1.000 72.87159  ? 71  THR L C   1 
ATOM   2235 O O   . THR B 2 71  ? 11.22373 20.68670  15.61471  1.000 83.85039  ? 71  THR L O   1 
ATOM   2236 C CB  . THR B 2 71  ? 12.41769 23.51652  15.40537  1.000 68.88971  ? 71  THR L CB  1 
ATOM   2237 O OG1 . THR B 2 71  ? 13.35193 24.59267  15.55648  1.000 76.58797  ? 71  THR L OG1 1 
ATOM   2238 C CG2 . THR B 2 71  ? 11.05468 23.94928  15.93127  1.000 89.54613  ? 71  THR L CG2 1 
ATOM   2239 N N   . LEU B 2 72  ? 11.42088 21.30498  17.77867  1.000 84.06378  ? 72  LEU L N   1 
ATOM   2240 C CA  . LEU B 2 72  ? 10.24515 20.59116  18.25687  1.000 87.34656  ? 72  LEU L CA  1 
ATOM   2241 C C   . LEU B 2 72  ? 9.23654  21.60597  18.77564  1.000 86.39970  ? 72  LEU L C   1 
ATOM   2242 O O   . LEU B 2 72  ? 9.57632  22.45400  19.60772  1.000 77.74304  ? 72  LEU L O   1 
ATOM   2243 C CB  . LEU B 2 72  ? 10.61231 19.59383  19.35792  1.000 78.96597  ? 72  LEU L CB  1 
ATOM   2244 C CG  . LEU B 2 72  ? 9.44044  18.91092  20.06689  1.000 81.73245  ? 72  LEU L CG  1 
ATOM   2245 C CD1 . LEU B 2 72  ? 8.74134  17.93364  19.13386  1.000 84.78224  ? 72  LEU L CD1 1 
ATOM   2246 C CD2 . LEU B 2 72  ? 9.90881  18.20899  21.33213  1.000 87.55535  ? 72  LEU L CD2 1 
ATOM   2247 N N   . THR B 2 73  ? 8.00377  21.52106  18.28351  1.000 84.32631  ? 73  THR L N   1 
ATOM   2248 C CA  . THR B 2 73  ? 6.96054  22.48418  18.60655  1.000 82.99211  ? 73  THR L CA  1 
ATOM   2249 C C   . THR B 2 73  ? 5.78871  21.77498  19.26822  1.000 77.59327  ? 73  THR L C   1 
ATOM   2250 O O   . THR B 2 73  ? 5.26408  20.79536  18.72802  1.000 74.07562  ? 73  THR L O   1 
ATOM   2251 C CB  . THR B 2 73  ? 6.48799  23.22272  17.35040  1.000 77.26940  ? 73  THR L CB  1 
ATOM   2252 O OG1 . THR B 2 73  ? 7.55628  24.02930  16.83843  1.000 73.19991  ? 73  THR L OG1 1 
ATOM   2253 C CG2 . THR B 2 73  ? 5.29497  24.11071  17.66821  1.000 84.33142  ? 73  THR L CG2 1 
ATOM   2254 N N   . ILE B 2 74  ? 5.38448  22.27168  20.43440  1.000 79.82451  ? 74  ILE L N   1 
ATOM   2255 C CA  . ILE B 2 74  ? 4.20095  21.79317  21.13871  1.000 85.87178  ? 74  ILE L CA  1 
ATOM   2256 C C   . ILE B 2 74  ? 3.24539  22.96846  21.28450  1.000 82.33442  ? 74  ILE L C   1 
ATOM   2257 O O   . ILE B 2 74  ? 3.61158  24.00589  21.85125  1.000 76.91148  ? 74  ILE L O   1 
ATOM   2258 C CB  . ILE B 2 74  ? 4.54856  21.19440  22.51116  1.000 91.05816  ? 74  ILE L CB  1 
ATOM   2259 C CG1 . ILE B 2 74  ? 5.53316  20.03329  22.35774  1.000 84.92024  ? 74  ILE L CG1 1 
ATOM   2260 C CG2 . ILE B 2 74  ? 3.28760  20.73309  23.22681  1.000 89.89807  ? 74  ILE L CG2 1 
ATOM   2261 C CD1 . ILE B 2 74  ? 6.73040  20.12196  23.27921  1.000 68.17021  ? 74  ILE L CD1 1 
ATOM   2262 N N   . SER B 2 75  ? 2.02869  22.80857  20.77529  1.000 84.15281  ? 75  SER L N   1 
ATOM   2263 C CA  . SER B 2 75  ? 1.00195  23.83531  20.85959  1.000 92.88156  ? 75  SER L CA  1 
ATOM   2264 C C   . SER B 2 75  ? 0.02350  23.50292  21.97815  1.000 102.31160 ? 75  SER L C   1 
ATOM   2265 O O   . SER B 2 75  ? -0.19362 22.33441  22.30592  1.000 108.30051 ? 75  SER L O   1 
ATOM   2266 C CB  . SER B 2 75  ? 0.25166  23.96921  19.53313  1.000 79.26011  ? 75  SER L CB  1 
ATOM   2267 O OG  . SER B 2 75  ? 1.13675  23.84611  18.43417  1.000 110.83341 ? 75  SER L OG  1 
ATOM   2268 N N   . ARG B 2 76  ? -0.56255 24.54615  22.56313  1.000 89.17455  ? 76  ARG L N   1 
ATOM   2269 C CA  . ARG B 2 76  ? -1.50984 24.40904  23.66824  1.000 90.52842  ? 76  ARG L CA  1 
ATOM   2270 C C   . ARG B 2 76  ? -0.92799 23.52082  24.76819  1.000 94.57579  ? 76  ARG L C   1 
ATOM   2271 O O   . ARG B 2 76  ? -1.45429 22.45575  25.09637  1.000 107.56970 ? 76  ARG L O   1 
ATOM   2272 C CB  . ARG B 2 76  ? -2.85424 23.86828  23.17268  1.000 100.60068 ? 76  ARG L CB  1 
ATOM   2273 C CG  . ARG B 2 76  ? -3.60203 24.81201  22.24397  1.000 102.47326 ? 76  ARG L CG  1 
ATOM   2274 C CD  . ARG B 2 76  ? -4.27923 24.05766  21.10840  1.000 122.75046 ? 76  ARG L CD  1 
ATOM   2275 N NE  . ARG B 2 76  ? -4.93764 22.84138  21.57098  1.000 138.14513 ? 76  ARG L NE  1 
ATOM   2276 C CZ  . ARG B 2 76  ? -4.86348 21.66842  20.95657  1.000 134.23248 ? 76  ARG L CZ  1 
ATOM   2277 N NH1 . ARG B 2 76  ? -4.16862 21.51492  19.84116  1.000 114.72827 ? 76  ARG L NH1 1 
ATOM   2278 N NH2 . ARG B 2 76  ? -5.50399 20.62347  21.47338  1.000 132.63784 ? 76  ARG L NH2 1 
ATOM   2279 N N   . VAL B 2 77  ? 0.19362  23.98193  25.32693  1.000 95.30023  ? 77  VAL L N   1 
ATOM   2280 C CA  . VAL B 2 77  ? 0.92580  23.18640  26.30442  1.000 94.31957  ? 77  VAL L CA  1 
ATOM   2281 C C   . VAL B 2 77  ? 0.06604  22.96499  27.53841  1.000 87.62908  ? 77  VAL L C   1 
ATOM   2282 O O   . VAL B 2 77  ? -0.54124 23.90131  28.07315  1.000 94.91885  ? 77  VAL L O   1 
ATOM   2283 C CB  . VAL B 2 77  ? 2.25301  23.87050  26.66277  1.000 80.22607  ? 77  VAL L CB  1 
ATOM   2284 C CG1 . VAL B 2 77  ? 3.14945  22.91416  27.43215  1.000 102.38369 ? 77  VAL L CG1 1 
ATOM   2285 C CG2 . VAL B 2 77  ? 2.95057  24.36304  25.40540  1.000 86.56794  ? 77  VAL L CG2 1 
ATOM   2286 N N   . GLU B 2 78  ? 0.00851  21.71839  27.99294  1.000 86.09666  ? 78  GLU L N   1 
ATOM   2287 C CA  . GLU B 2 78  ? -0.73519 21.33063  29.18069  1.000 105.00228 ? 78  GLU L CA  1 
ATOM   2288 C C   . GLU B 2 78  ? 0.23449  20.88270  30.27107  1.000 97.80107  ? 78  GLU L C   1 
ATOM   2289 O O   . GLU B 2 78  ? 1.45667  20.89314  30.09671  1.000 88.32429  ? 78  GLU L O   1 
ATOM   2290 C CB  . GLU B 2 78  ? -1.74553 20.22964  28.84652  1.000 111.33462 ? 78  GLU L CB  1 
ATOM   2291 C CG  . GLU B 2 78  ? -1.19602 19.12713  27.95264  1.000 119.00410 ? 78  GLU L CG  1 
ATOM   2292 C CD  . GLU B 2 78  ? -2.22109 18.04736  27.65783  1.000 131.76401 ? 78  GLU L CD  1 
ATOM   2293 O OE1 . GLU B 2 78  ? -3.20892 18.34002  26.95127  1.000 127.79761 ? 78  GLU L OE1 1 
ATOM   2294 O OE2 . GLU B 2 78  ? -2.03850 16.90573  28.13183  1.000 127.08056 ? 78  GLU L OE2 1 
ATOM   2295 N N   . ALA B 2 79  ? -0.32991 20.48866  31.41459  1.000 86.95179  ? 79  ALA L N   1 
ATOM   2296 C CA  . ALA B 2 79  ? 0.49569  20.03691  32.52953  1.000 71.59969  ? 79  ALA L CA  1 
ATOM   2297 C C   . ALA B 2 79  ? 1.24003  18.75280  32.18572  1.000 89.54082  ? 79  ALA L C   1 
ATOM   2298 O O   . ALA B 2 79  ? 2.39644  18.57377  32.58534  1.000 104.17633 ? 79  ALA L O   1 
ATOM   2299 C CB  . ALA B 2 79  ? -0.36683 19.84123  33.77564  1.000 93.15229  ? 79  ALA L CB  1 
ATOM   2300 N N   . GLY B 2 80  ? 0.59553  17.84919  31.44367  1.000 88.75431  ? 80  GLY L N   1 
ATOM   2301 C CA  . GLY B 2 80  ? 1.20386  16.56996  31.12186  1.000 78.75835  ? 80  GLY L CA  1 
ATOM   2302 C C   . GLY B 2 80  ? 2.43118  16.66536  30.24075  1.000 76.85953  ? 80  GLY L C   1 
ATOM   2303 O O   . GLY B 2 80  ? 3.23835  15.73010  30.22069  1.000 83.05065  ? 80  GLY L O   1 
ATOM   2304 N N   . ASP B 2 81  ? 2.59351  17.77309  29.51560  1.000 79.40818  ? 81  ASP L N   1 
ATOM   2305 C CA  . ASP B 2 81  ? 3.73935  17.94903  28.63211  1.000 91.21497  ? 81  ASP L CA  1 
ATOM   2306 C C   . ASP B 2 81  ? 5.02264  18.29081  29.37835  1.000 87.86849  ? 81  ASP L C   1 
ATOM   2307 O O   . ASP B 2 81  ? 6.08978  18.32220  28.75546  1.000 76.18167  ? 81  ASP L O   1 
ATOM   2308 C CB  . ASP B 2 81  ? 3.44495  19.03972  27.59789  1.000 86.55989  ? 81  ASP L CB  1 
ATOM   2309 C CG  . ASP B 2 81  ? 2.22628  18.72737  26.74991  1.000 90.32578  ? 81  ASP L CG  1 
ATOM   2310 O OD1 . ASP B 2 81  ? 1.83570  17.54286  26.67801  1.000 91.65386  ? 81  ASP L OD1 1 
ATOM   2311 O OD2 . ASP B 2 81  ? 1.65883  19.66772  26.15480  1.000 77.38279  ? 81  ASP L OD2 1 
ATOM   2312 N N   . GLU B 2 82  ? 4.94780  18.54742  30.68281  1.000 92.02130  ? 82  GLU L N   1 
ATOM   2313 C CA  . GLU B 2 82  ? 6.12860  18.88258  31.47323  1.000 73.20156  ? 82  GLU L CA  1 
ATOM   2314 C C   . GLU B 2 82  ? 7.02017  17.65378  31.60868  1.000 76.49874  ? 82  GLU L C   1 
ATOM   2315 O O   . GLU B 2 82  ? 6.66717  16.69526  32.30375  1.000 70.45411  ? 82  GLU L O   1 
ATOM   2316 C CB  . GLU B 2 82  ? 5.70889  19.40520  32.84362  1.000 78.19225  ? 82  GLU L CB  1 
ATOM   2317 C CG  . GLU B 2 82  ? 6.81300  20.11872  33.60619  1.000 98.55037  ? 82  GLU L CG  1 
ATOM   2318 C CD  . GLU B 2 82  ? 6.27843  20.98990  34.72630  1.000 106.32181 ? 82  GLU L CD  1 
ATOM   2319 O OE1 . GLU B 2 82  ? 5.04338  21.15393  34.81614  1.000 110.82756 ? 82  GLU L OE1 1 
ATOM   2320 O OE2 . GLU B 2 82  ? 7.09302  21.51001  35.51779  1.000 108.46870 ? 82  GLU L OE2 1 
ATOM   2321 N N   . ALA B 2 83  ? 8.17381  17.68262  30.95356  1.000 68.81421  ? 83  ALA L N   1 
ATOM   2322 C CA  . ALA B 2 83  ? 9.14478  16.59064  30.99027  1.000 67.66640  ? 83  ALA L CA  1 
ATOM   2323 C C   . ALA B 2 83  ? 10.45041 17.11087  30.39744  1.000 65.70584  ? 83  ALA L C   1 
ATOM   2324 O O   . ALA B 2 83  ? 10.58670 18.30612  30.10804  1.000 58.32958  ? 83  ALA L O   1 
ATOM   2325 C CB  . ALA B 2 83  ? 8.62948  15.35829  30.24436  1.000 68.34045  ? 83  ALA L CB  1 
ATOM   2326 N N   . ASP B 2 84  ? 11.41567 16.21271  30.22279  1.000 61.92882  ? 84  ASP L N   1 
ATOM   2327 C CA  . ASP B 2 84  ? 12.68065 16.53001  29.57421  1.000 71.18455  ? 84  ASP L CA  1 
ATOM   2328 C C   . ASP B 2 84  ? 12.68310 15.94126  28.17000  1.000 83.70752  ? 84  ASP L C   1 
ATOM   2329 O O   . ASP B 2 84  ? 12.41765 14.74772  27.99143  1.000 86.44835  ? 84  ASP L O   1 
ATOM   2330 C CB  . ASP B 2 84  ? 13.86484 15.99209  30.37952  1.000 78.96156  ? 84  ASP L CB  1 
ATOM   2331 C CG  . ASP B 2 84  ? 14.02823 16.69110  31.71597  1.000 88.15780  ? 84  ASP L CG  1 
ATOM   2332 O OD1 . ASP B 2 84  ? 13.25514 17.63114  31.99692  1.000 92.28434  ? 84  ASP L OD1 1 
ATOM   2333 O OD2 . ASP B 2 84  ? 14.93314 16.30260  32.48440  1.000 78.39872  ? 84  ASP L OD2 1 
ATOM   2334 N N   . TYR B 2 85  ? 12.98094 16.77754  27.18033  1.000 79.86719  ? 85  TYR L N   1 
ATOM   2335 C CA  . TYR B 2 85  ? 12.92620 16.39082  25.77775  1.000 60.88446  ? 85  TYR L CA  1 
ATOM   2336 C C   . TYR B 2 85  ? 14.33267 16.35158  25.19751  1.000 68.71453  ? 85  TYR L C   1 
ATOM   2337 O O   . TYR B 2 85  ? 15.12679 17.27268  25.41648  1.000 67.04284  ? 85  TYR L O   1 
ATOM   2338 C CB  . TYR B 2 85  ? 12.04393 17.35502  24.98204  1.000 63.41195  ? 85  TYR L CB  1 
ATOM   2339 C CG  . TYR B 2 85  ? 10.57040 17.21106  25.28969  1.000 76.35370  ? 85  TYR L CG  1 
ATOM   2340 C CD1 . TYR B 2 85  ? 9.97991  17.94114  26.31345  1.000 67.86451  ? 85  TYR L CD1 1 
ATOM   2341 C CD2 . TYR B 2 85  ? 9.77200  16.33615  24.56416  1.000 77.79901  ? 85  TYR L CD2 1 
ATOM   2342 C CE1 . TYR B 2 85  ? 8.63371  17.80922  26.60145  1.000 70.10236  ? 85  TYR L CE1 1 
ATOM   2343 C CE2 . TYR B 2 85  ? 8.42513  16.19735  24.84467  1.000 77.53777  ? 85  TYR L CE2 1 
ATOM   2344 C CZ  . TYR B 2 85  ? 7.86154  16.93558  25.86438  1.000 79.50122  ? 85  TYR L CZ  1 
ATOM   2345 O OH  . TYR B 2 85  ? 6.52153  16.80019  26.14738  1.000 79.75518  ? 85  TYR L OH  1 
ATOM   2346 N N   . TYR B 2 86  ? 14.63177 15.28652  24.45808  1.000 72.92986  ? 86  TYR L N   1 
ATOM   2347 C CA  . TYR B 2 86  ? 15.93679 15.07734  23.85167  1.000 73.27295  ? 86  TYR L CA  1 
ATOM   2348 C C   . TYR B 2 86  ? 15.79120 14.96583  22.34011  1.000 77.04439  ? 86  TYR L C   1 
ATOM   2349 O O   . TYR B 2 86  ? 14.77259 14.48627  21.83368  1.000 75.11197  ? 86  TYR L O   1 
ATOM   2350 C CB  . TYR B 2 86  ? 16.60568 13.80832  24.39808  1.000 64.07281  ? 86  TYR L CB  1 
ATOM   2351 C CG  . TYR B 2 86  ? 16.96563 13.87673  25.86555  1.000 74.36264  ? 86  TYR L CG  1 
ATOM   2352 C CD1 . TYR B 2 86  ? 16.02674 13.57888  26.84524  1.000 67.46271  ? 86  TYR L CD1 1 
ATOM   2353 C CD2 . TYR B 2 86  ? 18.24672 14.22691  26.27132  1.000 80.23491  ? 86  TYR L CD2 1 
ATOM   2354 C CE1 . TYR B 2 86  ? 16.35078 13.63726  28.18734  1.000 65.46174  ? 86  TYR L CE1 1 
ATOM   2355 C CE2 . TYR B 2 86  ? 18.58049 14.28653  27.61192  1.000 74.34677  ? 86  TYR L CE2 1 
ATOM   2356 C CZ  . TYR B 2 86  ? 17.62853 13.99125  28.56482  1.000 65.08345  ? 86  TYR L CZ  1 
ATOM   2357 O OH  . TYR B 2 86  ? 17.95508 14.04899  29.89999  1.000 74.35784  ? 86  TYR L OH  1 
ATOM   2358 N N   . CYS B 2 87  ? 16.81847 15.41265  21.62176  1.000 73.63845  ? 87  CYS L N   1 
ATOM   2359 C CA  . CYS B 2 87  ? 16.87915 15.28270  20.17298  1.000 71.26268  ? 87  CYS L CA  1 
ATOM   2360 C C   . CYS B 2 87  ? 17.93709 14.25246  19.80264  1.000 62.03372  ? 87  CYS L C   1 
ATOM   2361 O O   . CYS B 2 87  ? 19.00161 14.18846  20.42588  1.000 64.81053  ? 87  CYS L O   1 
ATOM   2362 C CB  . CYS B 2 87  ? 17.19172 16.62278  19.49890  1.000 65.91436  ? 87  CYS L CB  1 
ATOM   2363 S SG  . CYS B 2 87  ? 18.79825 17.33594  19.91492  1.000 90.33998  ? 87  CYS L SG  1 
ATOM   2364 N N   . GLN B 2 88  ? 17.63707 13.44275  18.79062  1.000 60.20972  ? 88  GLN L N   1 
ATOM   2365 C CA  . GLN B 2 88  ? 18.50931 12.34528  18.39767  1.000 66.44141  ? 88  GLN L CA  1 
ATOM   2366 C C   . GLN B 2 88  ? 18.62739 12.28844  16.88269  1.000 59.72219  ? 88  GLN L C   1 
ATOM   2367 O O   . GLN B 2 88  ? 17.61381 12.30468  16.17789  1.000 66.34181  ? 88  GLN L O   1 
ATOM   2368 C CB  . GLN B 2 88  ? 17.97821 11.01291  18.93445  1.000 68.20153  ? 88  GLN L CB  1 
ATOM   2369 C CG  . GLN B 2 88  ? 18.74477 9.80948   18.44233  1.000 71.01778  ? 88  GLN L CG  1 
ATOM   2370 C CD  . GLN B 2 88  ? 17.84070 8.63575   18.13230  1.000 72.80751  ? 88  GLN L CD  1 
ATOM   2371 O OE1 . GLN B 2 88  ? 17.34224 7.96475   19.03410  1.000 86.30259  ? 88  GLN L OE1 1 
ATOM   2372 N NE2 . GLN B 2 88  ? 17.61834 8.38638   16.84916  1.000 78.61963  ? 88  GLN L NE2 1 
ATOM   2373 N N   . VAL B 2 89  ? 19.86364 12.21710  16.38820  1.000 49.29302  ? 89  VAL L N   1 
ATOM   2374 C CA  . VAL B 2 89  ? 20.11926 12.05006  14.96117  1.000 86.60512  ? 89  VAL L CA  1 
ATOM   2375 C C   . VAL B 2 89  ? 21.01912 10.83886  14.75740  1.000 93.94072  ? 89  VAL L C   1 
ATOM   2376 O O   . VAL B 2 89  ? 21.44345 10.19564  15.72412  1.000 73.28514  ? 89  VAL L O   1 
ATOM   2377 C CB  . VAL B 2 89  ? 20.74938 13.31193  14.34254  1.000 83.38120  ? 89  VAL L CB  1 
ATOM   2378 C CG1 . VAL B 2 89  ? 19.80067 14.49823  14.45974  1.000 98.43837  ? 89  VAL L CG1 1 
ATOM   2379 C CG2 . VAL B 2 89  ? 22.08989 13.61343  14.99379  1.000 79.49062  ? 89  VAL L CG2 1 
ATOM   2380 N N   . TRP B 2 90  ? 21.31694 10.52255  13.50004  1.000 98.43524  ? 90  TRP L N   1 
ATOM   2381 C CA  . TRP B 2 90  ? 22.16386 9.38701   13.14079  1.000 84.01207  ? 90  TRP L CA  1 
ATOM   2382 C C   . TRP B 2 90  ? 23.31498 9.90971   12.28884  1.000 93.41254  ? 90  TRP L C   1 
ATOM   2383 O O   . TRP B 2 90  ? 23.14924 10.14191  11.08697  1.000 90.02046  ? 90  TRP L O   1 
ATOM   2384 C CB  . TRP B 2 90  ? 21.37514 8.31490   12.39123  1.000 87.11050  ? 90  TRP L CB  1 
ATOM   2385 C CG  . TRP B 2 90  ? 20.00118 8.04672   12.92973  1.000 89.05461  ? 90  TRP L CG  1 
ATOM   2386 C CD1 . TRP B 2 90  ? 18.90009 8.84604   12.81145  1.000 87.76078  ? 90  TRP L CD1 1 
ATOM   2387 C CD2 . TRP B 2 90  ? 19.57561 6.88293   13.64871  1.000 80.59336  ? 90  TRP L CD2 1 
ATOM   2388 N NE1 . TRP B 2 90  ? 17.82056 8.25821   13.42464  1.000 86.18644  ? 90  TRP L NE1 1 
ATOM   2389 C CE2 . TRP B 2 90  ? 18.20839 7.05155   13.94487  1.000 79.42249  ? 90  TRP L CE2 1 
ATOM   2390 C CE3 . TRP B 2 90  ? 20.21943 5.71746   14.07546  1.000 79.73194  ? 90  TRP L CE3 1 
ATOM   2391 C CZ2 . TRP B 2 90  ? 17.47431 6.09888   14.64679  1.000 75.71961  ? 90  TRP L CZ2 1 
ATOM   2392 C CZ3 . TRP B 2 90  ? 19.48894 4.77393   14.77337  1.000 67.53739  ? 90  TRP L CZ3 1 
ATOM   2393 C CH2 . TRP B 2 90  ? 18.13184 4.97110   15.05306  1.000 76.57522  ? 90  TRP L CH2 1 
ATOM   2394 N N   . ASP B 2 91  ? 24.47845 10.09633  12.90697  1.000 98.36624  ? 91  ASP L N   1 
ATOM   2395 C CA  . ASP B 2 91  ? 25.66800 10.50715  12.16866  1.000 104.98335 ? 91  ASP L CA  1 
ATOM   2396 C C   . ASP B 2 91  ? 26.09605 9.37282   11.24609  1.000 109.77264 ? 91  ASP L C   1 
ATOM   2397 O O   . ASP B 2 91  ? 26.59408 8.34146   11.70778  1.000 106.58949 ? 91  ASP L O   1 
ATOM   2398 C CB  . ASP B 2 91  ? 26.78867 10.88531  13.13252  1.000 104.18736 ? 91  ASP L CB  1 
ATOM   2399 C CG  . ASP B 2 91  ? 28.09457 11.18207  12.41987  1.000 124.07783 ? 91  ASP L CG  1 
ATOM   2400 O OD1 . ASP B 2 91  ? 28.15497 12.18732  11.68044  1.000 137.73752 ? 91  ASP L OD1 1 
ATOM   2401 O OD2 . ASP B 2 91  ? 29.06086 10.41150  12.59954  1.000 119.64134 ? 91  ASP L OD2 1 
ATOM   2402 N N   . SER B 2 92  ? 25.90670 9.55950   9.94075   1.000 102.16673 ? 92  SER L N   1 
ATOM   2403 C CA  . SER B 2 92  ? 26.20926 8.51780   8.96759   1.000 104.63575 ? 92  SER L CA  1 
ATOM   2404 C C   . SER B 2 92  ? 27.69758 8.39609   8.67262   1.000 115.12625 ? 92  SER L C   1 
ATOM   2405 O O   . SER B 2 92  ? 28.08652 7.52887   7.88300   1.000 116.87855 ? 92  SER L O   1 
ATOM   2406 C CB  . SER B 2 92  ? 25.44377 8.77135   7.66587   1.000 108.69516 ? 92  SER L CB  1 
ATOM   2407 O OG  . SER B 2 92  ? 25.22194 7.56081   6.96237   1.000 108.66609 ? 92  SER L OG  1 
ATOM   2408 N N   . ASP B 2 93  ? 28.53400 9.24346   9.27286   1.000 115.49468 ? 93  ASP L N   1 
ATOM   2409 C CA  . ASP B 2 93  ? 29.97625 9.09526   9.13800   1.000 121.28486 ? 93  ASP L CA  1 
ATOM   2410 C C   . ASP B 2 93  ? 30.54061 8.03277   10.07107  1.000 131.44551 ? 93  ASP L C   1 
ATOM   2411 O O   . ASP B 2 93  ? 31.66565 7.56979   9.85330   1.000 131.58538 ? 93  ASP L O   1 
ATOM   2412 C CB  . ASP B 2 93  ? 30.66781 10.43440  9.39968   1.000 124.44834 ? 93  ASP L CB  1 
ATOM   2413 C CG  . ASP B 2 93  ? 30.13432 11.54566  8.51881   1.000 143.69618 ? 93  ASP L CG  1 
ATOM   2414 O OD1 . ASP B 2 93  ? 29.83206 11.27547  7.33717   1.000 153.07567 ? 93  ASP L OD1 1 
ATOM   2415 O OD2 . ASP B 2 93  ? 30.01244 12.68768  9.00899   1.000 147.08696 ? 93  ASP L OD2 1 
ATOM   2416 N N   . SER B 2 94  ? 29.78885 7.64113   11.10257  1.000 126.52726 ? 94  SER L N   1 
ATOM   2417 C CA  . SER B 2 94  ? 30.21354 6.57805   12.00149  1.000 123.42389 ? 94  SER L CA  1 
ATOM   2418 C C   . SER B 2 94  ? 29.09021 5.62681   12.39204  1.000 127.21718 ? 94  SER L C   1 
ATOM   2419 O O   . SER B 2 94  ? 29.35792 4.65320   13.10393  1.000 127.97529 ? 94  SER L O   1 
ATOM   2420 C CB  . SER B 2 94  ? 30.83856 7.17377   13.27405  1.000 123.78478 ? 94  SER L CB  1 
ATOM   2421 O OG  . SER B 2 94  ? 29.88435 7.92216   14.00736  1.000 126.88601 ? 94  SER L OG  1 
ATOM   2422 N N   . ASP B 2 95  ? 27.85685 5.86395   11.94039  1.000 121.88519 ? 95  ASP L N   1 
ATOM   2423 C CA  . ASP B 2 95  ? 26.68667 5.07802   12.33912  1.000 121.70219 ? 95  ASP L CA  1 
ATOM   2424 C C   . ASP B 2 95  ? 26.53676 5.05360   13.85956  1.000 119.62840 ? 95  ASP L C   1 
ATOM   2425 O O   . ASP B 2 95  ? 26.35675 4.00323   14.47929  1.000 112.60646 ? 95  ASP L O   1 
ATOM   2426 C CB  . ASP B 2 95  ? 26.75032 3.65903   11.76875  1.000 128.76479 ? 95  ASP L CB  1 
ATOM   2427 C CG  . ASP B 2 95  ? 25.37890 3.09969   11.43801  1.000 133.07329 ? 95  ASP L CG  1 
ATOM   2428 O OD1 . ASP B 2 95  ? 24.42167 3.89423   11.32497  1.000 130.46419 ? 95  ASP L OD1 1 
ATOM   2429 O OD2 . ASP B 2 95  ? 25.25852 1.86519   11.28991  1.000 121.55053 ? 95  ASP L OD2 1 
ATOM   2430 N N   . HIS B 2 96  ? 26.61839 6.23653   14.46323  1.000 103.99756 ? 96  HIS L N   1 
ATOM   2431 C CA  . HIS B 2 96  ? 26.48494 6.40381   15.90359  1.000 81.30733  ? 96  HIS L CA  1 
ATOM   2432 C C   . HIS B 2 96  ? 25.26029 7.25456   16.20181  1.000 86.02965  ? 96  HIS L C   1 
ATOM   2433 O O   . HIS B 2 96  ? 25.04918 8.29282   15.56607  1.000 89.48873  ? 96  HIS L O   1 
ATOM   2434 C CB  . HIS B 2 96  ? 27.74319 7.03258   16.50415  1.000 106.71721 ? 96  HIS L CB  1 
ATOM   2435 C CG  . HIS B 2 96  ? 28.96075 6.17040   16.37909  1.000 113.55970 ? 96  HIS L CG  1 
ATOM   2436 N ND1 . HIS B 2 96  ? 30.23936 6.65099   16.56288  1.000 128.02953 ? 96  HIS L ND1 1 
ATOM   2437 C CD2 . HIS B 2 96  ? 29.09170 4.85176   16.09983  1.000 105.70905 ? 96  HIS L CD2 1 
ATOM   2438 C CE1 . HIS B 2 96  ? 31.10569 5.66740   16.39537  1.000 116.20026 ? 96  HIS L CE1 1 
ATOM   2439 N NE2 . HIS B 2 96  ? 30.43504 4.56507   16.11319  1.000 105.63151 ? 96  HIS L NE2 1 
ATOM   2440 N N   . VAL B 2 97  ? 24.45890 6.80745   17.16668  1.000 86.76299  ? 97  VAL L N   1 
ATOM   2441 C CA  . VAL B 2 97  ? 23.17519 7.43765   17.48005  1.000 81.68015  ? 97  VAL L CA  1 
ATOM   2442 C C   . VAL B 2 97  ? 23.44416 8.46184   18.57967  1.000 65.86989  ? 97  VAL L C   1 
ATOM   2443 O O   . VAL B 2 97  ? 23.27930 8.19167   19.76673  1.000 80.68043  ? 97  VAL L O   1 
ATOM   2444 C CB  . VAL B 2 97  ? 22.12474 6.40703   17.88631  1.000 83.72981  ? 97  VAL L CB  1 
ATOM   2445 C CG1 . VAL B 2 97  ? 20.73878 6.98397   17.74826  1.000 78.45745  ? 97  VAL L CG1 1 
ATOM   2446 C CG2 . VAL B 2 97  ? 22.26815 5.14106   17.04741  1.000 83.54725  ? 97  VAL L CG2 1 
ATOM   2447 N N   . VAL B 2 98  ? 23.84565 9.66313   18.17681  1.000 72.24231  ? 98  VAL L N   1 
ATOM   2448 C CA  . VAL B 2 98  ? 24.20332 10.70815  19.13145  1.000 65.81821  ? 98  VAL L CA  1 
ATOM   2449 C C   . VAL B 2 98  ? 22.93865 11.37302  19.66139  1.000 62.84115  ? 98  VAL L C   1 
ATOM   2450 O O   . VAL B 2 98  ? 22.06038 11.77799  18.89022  1.000 60.61839  ? 98  VAL L O   1 
ATOM   2451 C CB  . VAL B 2 98  ? 25.14857 11.73491  18.48746  1.000 71.59274  ? 98  VAL L CB  1 
ATOM   2452 C CG1 . VAL B 2 98  ? 26.55086 11.15926  18.38039  1.000 97.15633  ? 98  VAL L CG1 1 
ATOM   2453 C CG2 . VAL B 2 98  ? 24.63927 12.14547  17.11636  1.000 101.25847 ? 98  VAL L CG2 1 
ATOM   2454 N N   . PHE B 2 99  ? 22.84278 11.48053  20.98388  1.000 77.72137  ? 99  PHE L N   1 
ATOM   2455 C CA  . PHE B 2 99  ? 21.71051 12.10886  21.64638  1.000 65.57635  ? 99  PHE L CA  1 
ATOM   2456 C C   . PHE B 2 99  ? 22.00582 13.57776  21.94518  1.000 62.56496  ? 99  PHE L C   1 
ATOM   2457 O O   . PHE B 2 99  ? 23.14934 14.03516  21.89683  1.000 70.13199  ? 99  PHE L O   1 
ATOM   2458 C CB  . PHE B 2 99  ? 21.36607 11.37071  22.94134  1.000 49.00599  ? 99  PHE L CB  1 
ATOM   2459 C CG  . PHE B 2 99  ? 20.41534 10.22283  22.75597  1.000 55.49474  ? 99  PHE L CG  1 
ATOM   2460 C CD1 . PHE B 2 99  ? 19.04887 10.44202  22.69678  1.000 54.52381  ? 99  PHE L CD1 1 
ATOM   2461 C CD2 . PHE B 2 99  ? 20.88624 8.92359   22.65629  1.000 61.16564  ? 99  PHE L CD2 1 
ATOM   2462 C CE1 . PHE B 2 99  ? 18.16923 9.38860   22.53065  1.000 65.44661  ? 99  PHE L CE1 1 
ATOM   2463 C CE2 . PHE B 2 99  ? 20.01188 7.86506   22.49065  1.000 62.80093  ? 99  PHE L CE2 1 
ATOM   2464 C CZ  . PHE B 2 99  ? 18.65163 8.09794   22.42799  1.000 68.01674  ? 99  PHE L CZ  1 
ATOM   2465 N N   . GLY B 2 100 ? 20.94310 14.32388  22.26491  1.000 62.33709  ? 100 GLY L N   1 
ATOM   2466 C CA  . GLY B 2 100 ? 21.08153 15.72289  22.60865  1.000 66.04552  ? 100 GLY L CA  1 
ATOM   2467 C C   . GLY B 2 100 ? 21.32845 15.94609  24.09193  1.000 73.66949  ? 100 GLY L C   1 
ATOM   2468 O O   . GLY B 2 100 ? 21.25505 15.03048  24.90977  1.000 77.39713  ? 100 GLY L O   1 
ATOM   2469 N N   . GLY B 2 101 ? 21.62770 17.20152  24.42989  1.000 71.11799  ? 101 GLY L N   1 
ATOM   2470 C CA  . GLY B 2 101 ? 21.89136 17.53895  25.81926  1.000 79.28849  ? 101 GLY L CA  1 
ATOM   2471 C C   . GLY B 2 101 ? 20.66720 17.39956  26.70396  1.000 72.62622  ? 101 GLY L C   1 
ATOM   2472 O O   . GLY B 2 101 ? 20.75899 16.91032  27.83312  1.000 64.17525  ? 101 GLY L O   1 
ATOM   2473 N N   . GLY B 2 102 ? 19.50885 17.82598  26.20834  1.000 83.16786  ? 102 GLY L N   1 
ATOM   2474 C CA  . GLY B 2 102 ? 18.28278 17.74856  26.97633  1.000 65.91881  ? 102 GLY L CA  1 
ATOM   2475 C C   . GLY B 2 102 ? 17.70842 19.10858  27.31044  1.000 78.10395  ? 102 GLY L C   1 
ATOM   2476 O O   . GLY B 2 102 ? 18.45326 20.07034  27.52182  1.000 75.81379  ? 102 GLY L O   1 
ATOM   2477 N N   . THR B 2 103 ? 16.38121 19.20178  27.35916  1.000 82.53414  ? 103 THR L N   1 
ATOM   2478 C CA  . THR B 2 103 ? 15.69793 20.45465  27.65951  1.000 69.46769  ? 103 THR L CA  1 
ATOM   2479 C C   . THR B 2 103 ? 14.58595 20.17838  28.65726  1.000 77.52804  ? 103 THR L C   1 
ATOM   2480 O O   . THR B 2 103 ? 13.71683 19.34015  28.40110  1.000 84.13722  ? 103 THR L O   1 
ATOM   2481 C CB  . THR B 2 103 ? 15.12900 21.09651  26.38976  1.000 72.82807  ? 103 THR L CB  1 
ATOM   2482 O OG1 . THR B 2 103 ? 16.18533 21.31061  25.44536  1.000 83.79291  ? 103 THR L OG1 1 
ATOM   2483 C CG2 . THR B 2 103 ? 14.47063 22.42772  26.71511  1.000 69.63251  ? 103 THR L CG2 1 
ATOM   2484 N N   . LYS B 2 104 ? 14.61191 20.88100  29.78730  1.000 77.99698  ? 104 LYS L N   1 
ATOM   2485 C CA  . LYS B 2 104 ? 13.56296 20.76861  30.79849  1.000 74.90394  ? 104 LYS L CA  1 
ATOM   2486 C C   . LYS B 2 104 ? 12.44759 21.73780  30.42973  1.000 83.15748  ? 104 LYS L C   1 
ATOM   2487 O O   . LYS B 2 104 ? 12.57775 22.95119  30.60810  1.000 85.15208  ? 104 LYS L O   1 
ATOM   2488 C CB  . LYS B 2 104 ? 14.11468 21.05582  32.19022  1.000 78.39786  ? 104 LYS L CB  1 
ATOM   2489 C CG  . LYS B 2 104 ? 13.08789 20.89777  33.30260  1.000 86.06213  ? 104 LYS L CG  1 
ATOM   2490 C CD  . LYS B 2 104 ? 13.74787 20.81483  34.66983  1.000 86.83643  ? 104 LYS L CD  1 
ATOM   2491 C CE  . LYS B 2 104 ? 12.92709 19.96202  35.62602  1.000 87.84785  ? 104 LYS L CE  1 
ATOM   2492 N NZ  . LYS B 2 104 ? 13.66583 19.65863  36.88366  1.000 96.10504  ? 104 LYS L NZ  1 
ATOM   2493 N N   . LEU B 2 105 ? 11.34561 21.20202  29.91078  1.000 76.65627  ? 105 LEU L N   1 
ATOM   2494 C CA  . LEU B 2 105 ? 10.19734 22.02033  29.53710  1.000 78.04477  ? 105 LEU L CA  1 
ATOM   2495 C C   . LEU B 2 105 ? 9.33484  22.24510  30.77179  1.000 89.52089  ? 105 LEU L C   1 
ATOM   2496 O O   . LEU B 2 105 ? 8.70149  21.31150  31.27504  1.000 80.54249  ? 105 LEU L O   1 
ATOM   2497 C CB  . LEU B 2 105 ? 9.40026  21.35169  28.42159  1.000 86.14788  ? 105 LEU L CB  1 
ATOM   2498 C CG  . LEU B 2 105 ? 8.19043  22.13839  27.91498  1.000 81.29563  ? 105 LEU L CG  1 
ATOM   2499 C CD1 . LEU B 2 105 ? 8.62319  23.19334  26.91217  1.000 78.85236  ? 105 LEU L CD1 1 
ATOM   2500 C CD2 . LEU B 2 105 ? 7.16037  21.20221  27.30287  1.000 89.77352  ? 105 LEU L CD2 1 
ATOM   2501 N N   . THR B 2 106 ? 9.30883  23.48181  31.25956  1.000 94.92891  ? 106 THR L N   1 
ATOM   2502 C CA  . THR B 2 106 ? 8.57006  23.83966  32.46263  1.000 83.48678  ? 106 THR L CA  1 
ATOM   2503 C C   . THR B 2 106 ? 7.26872  24.52682  32.06904  1.000 83.65933  ? 106 THR L C   1 
ATOM   2504 O O   . THR B 2 106 ? 7.28851  25.58056  31.42337  1.000 83.57710  ? 106 THR L O   1 
ATOM   2505 C CB  . THR B 2 106 ? 9.40245  24.75277  33.36315  1.000 83.24333  ? 106 THR L CB  1 
ATOM   2506 O OG1 . THR B 2 106 ? 10.71112 24.19467  33.53616  1.000 83.91853  ? 106 THR L OG1 1 
ATOM   2507 C CG2 . THR B 2 106 ? 8.73783  24.90902  34.72299  1.000 80.62991  ? 106 THR L CG2 1 
ATOM   2508 N N   . VAL B 2 107 ? 6.14585  23.93031  32.45580  1.000 82.70276  ? 107 VAL L N   1 
ATOM   2509 C CA  . VAL B 2 107 ? 4.83435  24.53937  32.26899  1.000 82.26389  ? 107 VAL L CA  1 
ATOM   2510 C C   . VAL B 2 107 ? 4.54497  25.37411  33.51071  1.000 89.03435  ? 107 VAL L C   1 
ATOM   2511 O O   . VAL B 2 107 ? 4.25852  24.83188  34.58128  1.000 94.54256  ? 107 VAL L O   1 
ATOM   2512 C CB  . VAL B 2 107 ? 3.74776  23.48398  32.03535  1.000 89.74133  ? 107 VAL L CB  1 
ATOM   2513 C CG1 . VAL B 2 107 ? 2.48182  24.13660  31.50299  1.000 79.99921  ? 107 VAL L CG1 1 
ATOM   2514 C CG2 . VAL B 2 107 ? 4.24669  22.41521  31.07421  1.000 93.71101  ? 107 VAL L CG2 1 
ATOM   2515 N N   . LEU B 2 108 ? 4.62280  26.69696  33.36627  1.000 86.41650  ? 108 LEU L N   1 
ATOM   2516 C CA  . LEU B 2 108 ? 4.53599  27.60839  34.50134  1.000 85.71962  ? 108 LEU L CA  1 
ATOM   2517 C C   . LEU B 2 108 ? 3.19512  27.50117  35.21767  1.000 79.14817  ? 108 LEU L C   1 
ATOM   2518 O O   . LEU B 2 108 ? 2.15062  27.84096  34.65324  1.000 77.25899  ? 108 LEU L O   1 
ATOM   2519 C CB  . LEU B 2 108 ? 4.77739  29.04719  34.03960  1.000 68.74492  ? 108 LEU L CB  1 
ATOM   2520 C CG  . LEU B 2 108 ? 6.08668  29.29125  33.28538  1.000 68.54523  ? 108 LEU L CG  1 
ATOM   2521 C CD1 . LEU B 2 108 ? 6.16536  30.72709  32.79053  1.000 77.40734  ? 108 LEU L CD1 1 
ATOM   2522 C CD2 . LEU B 2 108 ? 7.28558  28.95411  34.15990  1.000 75.51989  ? 108 LEU L CD2 1 
ATOM   2523 N N   . GLY B 2 109 ? 3.21900  27.03224  36.46316  1.000 79.39389  ? 109 GLY L N   1 
ATOM   2524 C CA  . GLY B 2 109 ? 2.01275  26.91733  37.25905  1.000 98.64956  ? 109 GLY L CA  1 
ATOM   2525 C C   . GLY B 2 109 ? 2.00126  27.87231  38.43431  1.000 93.97186  ? 109 GLY L C   1 
ATOM   2526 O O   . GLY B 2 109 ? 0.94280  28.17838  38.99175  1.000 89.68872  ? 109 GLY L O   1 
ATOM   2527 N N   . GLN B 2 110 ? 3.17764  28.34338  38.81939  1.000 89.87965  ? 110 GLN L N   1 
ATOM   2528 C CA  . GLN B 2 110 ? 3.35920  29.31439  39.88475  1.000 79.18579  ? 110 GLN L CA  1 
ATOM   2529 C C   . GLN B 2 110 ? 4.28316  30.41348  39.38712  1.000 79.16821  ? 110 GLN L C   1 
ATOM   2530 O O   . GLN B 2 110 ? 5.04878  30.20662  38.43907  1.000 80.08730  ? 110 GLN L O   1 
ATOM   2531 C CB  . GLN B 2 110 ? 3.93879  28.65444  41.14627  1.000 83.22745  ? 110 GLN L CB  1 
ATOM   2532 C CG  . GLN B 2 110 ? 5.42861  28.36898  41.08809  1.000 80.94115  ? 110 GLN L CG  1 
ATOM   2533 C CD  . GLN B 2 110 ? 6.09006  28.48038  42.44785  1.000 100.96905 ? 110 GLN L CD  1 
ATOM   2534 O OE1 . GLN B 2 110 ? 6.24943  27.48642  43.15731  1.000 103.80349 ? 110 GLN L OE1 1 
ATOM   2535 N NE2 . GLN B 2 110 ? 6.47558  29.69585  42.82057  1.000 96.96713  ? 110 GLN L NE2 1 
ATOM   2536 N N   . PRO B 2 111 ? 4.21794  31.60449  39.98522  1.000 85.26295  ? 111 PRO L N   1 
ATOM   2537 C CA  . PRO B 2 111 ? 5.06951  32.70695  39.51918  1.000 66.77164  ? 111 PRO L CA  1 
ATOM   2538 C C   . PRO B 2 111 ? 6.54851  32.36126  39.61872  1.000 76.70734  ? 111 PRO L C   1 
ATOM   2539 O O   . PRO B 2 111 ? 6.98802  31.67979  40.54750  1.000 94.77331  ? 111 PRO L O   1 
ATOM   2540 C CB  . PRO B 2 111 ? 4.69668  33.86491  40.45448  1.000 68.69518  ? 111 PRO L CB  1 
ATOM   2541 C CG  . PRO B 2 111 ? 4.01130  33.21824  41.62519  1.000 87.76833  ? 111 PRO L CG  1 
ATOM   2542 C CD  . PRO B 2 111 ? 3.29790  32.04241  41.04732  1.000 94.95058  ? 111 PRO L CD  1 
ATOM   2543 N N   . LYS B 2 112 ? 7.31390  32.83843  38.63951  1.000 69.94476  ? 112 LYS L N   1 
ATOM   2544 C CA  . LYS B 2 112 ? 8.74193  32.55521  38.58798  1.000 72.90951  ? 112 LYS L CA  1 
ATOM   2545 C C   . LYS B 2 112 ? 9.46294  33.26272  39.72928  1.000 80.59395  ? 112 LYS L C   1 
ATOM   2546 O O   . LYS B 2 112 ? 9.23600  34.45007  39.98188  1.000 65.72578  ? 112 LYS L O   1 
ATOM   2547 C CB  . LYS B 2 112 ? 9.31480  32.99182  37.24047  1.000 58.99580  ? 112 LYS L CB  1 
ATOM   2548 C CG  . LYS B 2 112 ? 8.59894  32.38038  36.04400  1.000 82.04253  ? 112 LYS L CG  1 
ATOM   2549 C CD  . LYS B 2 112 ? 9.56158  32.07205  34.90944  1.000 77.56932  ? 112 LYS L CD  1 
ATOM   2550 C CE  . LYS B 2 112 ? 9.48869  33.13085  33.82120  1.000 78.99097  ? 112 LYS L CE  1 
ATOM   2551 N NZ  . LYS B 2 112 ? 9.68350  32.54857  32.46487  1.000 96.99189  ? 112 LYS L NZ  1 
ATOM   2552 N N   . ALA B 2 113 ? 10.33561 32.53293  40.41505  1.000 75.18666  ? 113 ALA L N   1 
ATOM   2553 C CA  . ALA B 2 113 ? 11.04312 33.03087  41.58393  1.000 64.13604  ? 113 ALA L CA  1 
ATOM   2554 C C   . ALA B 2 113 ? 12.52528 33.20769  41.26816  1.000 71.94731  ? 113 ALA L C   1 
ATOM   2555 O O   . ALA B 2 113 ? 12.99668 32.90654  40.16811  1.000 83.64112  ? 113 ALA L O   1 
ATOM   2556 C CB  . ALA B 2 113 ? 10.84203 32.08809  42.77223  1.000 76.23064  ? 113 ALA L CB  1 
ATOM   2557 N N   . ALA B 2 114 ? 13.26409 33.70285  42.26095  1.000 82.72953  ? 114 ALA L N   1 
ATOM   2558 C CA  . ALA B 2 114 ? 14.69265 33.92889  42.15576  1.000 62.97473  ? 114 ALA L CA  1 
ATOM   2559 C C   . ALA B 2 114 ? 15.43139 33.11947  43.21419  1.000 73.49561  ? 114 ALA L C   1 
ATOM   2560 O O   . ALA B 2 114 ? 14.93420 32.97023  44.33574  1.000 78.86751  ? 114 ALA L O   1 
ATOM   2561 C CB  . ALA B 2 114 ? 15.02931 35.41841  42.32051  1.000 60.36197  ? 114 ALA L CB  1 
ATOM   2562 N N   . PRO B 2 115 ? 16.60894 32.58727  42.89459  1.000 72.79226  ? 115 PRO L N   1 
ATOM   2563 C CA  . PRO B 2 115 ? 17.31042 31.72774  43.85313  1.000 67.49363  ? 115 PRO L CA  1 
ATOM   2564 C C   . PRO B 2 115 ? 17.77132 32.49190  45.08353  1.000 87.28990  ? 115 PRO L C   1 
ATOM   2565 O O   . PRO B 2 115 ? 18.11650 33.67481  45.02325  1.000 86.14784  ? 115 PRO L O   1 
ATOM   2566 C CB  . PRO B 2 115 ? 18.50409 31.20216  43.04802  1.000 54.14849  ? 115 PRO L CB  1 
ATOM   2567 C CG  . PRO B 2 115 ? 18.74344 32.25267  42.01896  1.000 80.21201  ? 115 PRO L CG  1 
ATOM   2568 C CD  . PRO B 2 115 ? 17.38027 32.77482  41.65362  1.000 81.52220  ? 115 PRO L CD  1 
ATOM   2569 N N   . SER B 2 116 ? 17.77322 31.78890  46.21241  1.000 83.08537  ? 116 SER L N   1 
ATOM   2570 C CA  . SER B 2 116 ? 18.29679 32.29858  47.47277  1.000 74.82283  ? 116 SER L CA  1 
ATOM   2571 C C   . SER B 2 116 ? 19.54653 31.50103  47.81734  1.000 74.16595  ? 116 SER L C   1 
ATOM   2572 O O   . SER B 2 116 ? 19.49892 30.26816  47.88693  1.000 75.18273  ? 116 SER L O   1 
ATOM   2573 C CB  . SER B 2 116 ? 17.25491 32.19062  48.58610  1.000 76.03830  ? 116 SER L CB  1 
ATOM   2574 O OG  . SER B 2 116 ? 17.87011 32.18787  49.86189  1.000 98.99540  ? 116 SER L OG  1 
ATOM   2575 N N   . VAL B 2 117 ? 20.65736 32.20097  48.03121  1.000 75.81783  ? 117 VAL L N   1 
ATOM   2576 C CA  . VAL B 2 117 ? 21.96522 31.57943  48.19965  1.000 73.58130  ? 117 VAL L CA  1 
ATOM   2577 C C   . VAL B 2 117 ? 22.46333 31.85077  49.61132  1.000 71.17198  ? 117 VAL L C   1 
ATOM   2578 O O   . VAL B 2 117 ? 22.44768 32.99812  50.07208  1.000 79.81152  ? 117 VAL L O   1 
ATOM   2579 C CB  . VAL B 2 117 ? 22.97526 32.09576  47.15843  1.000 66.47981  ? 117 VAL L CB  1 
ATOM   2580 C CG1 . VAL B 2 117 ? 24.21248 31.21567  47.13892  1.000 75.26924  ? 117 VAL L CG1 1 
ATOM   2581 C CG2 . VAL B 2 117 ? 22.33473 32.14982  45.78085  1.000 79.96724  ? 117 VAL L CG2 1 
ATOM   2582 N N   . THR B 2 118 ? 22.89920 30.79342  50.29369  1.000 64.29115  ? 118 THR L N   1 
ATOM   2583 C CA  . THR B 2 118 ? 23.53792 30.89721  51.60048  1.000 86.34321  ? 118 THR L CA  1 
ATOM   2584 C C   . THR B 2 118 ? 24.78853 30.03270  51.58578  1.000 83.77831  ? 118 THR L C   1 
ATOM   2585 O O   . THR B 2 118 ? 24.69899 28.81267  51.41398  1.000 84.67265  ? 118 THR L O   1 
ATOM   2586 C CB  . THR B 2 118 ? 22.59391 30.46096  52.72514  1.000 76.03362  ? 118 THR L CB  1 
ATOM   2587 O OG1 . THR B 2 118 ? 21.34023 31.14236  52.59191  1.000 81.47773  ? 118 THR L OG1 1 
ATOM   2588 C CG2 . THR B 2 118 ? 23.19955 30.78431  54.08227  1.000 65.66368  ? 118 THR L CG2 1 
ATOM   2589 N N   . LEU B 2 119 ? 25.94690 30.66116  51.76147  1.000 79.38084  ? 119 LEU L N   1 
ATOM   2590 C CA  . LEU B 2 119 ? 27.23401 29.98275  51.69619  1.000 70.14548  ? 119 LEU L CA  1 
ATOM   2591 C C   . LEU B 2 119 ? 27.84721 29.91323  53.08808  1.000 73.03460  ? 119 LEU L C   1 
ATOM   2592 O O   . LEU B 2 119 ? 27.92986 30.92916  53.78667  1.000 73.67453  ? 119 LEU L O   1 
ATOM   2593 C CB  . LEU B 2 119 ? 28.17753 30.70280  50.73037  1.000 60.32975  ? 119 LEU L CB  1 
ATOM   2594 C CG  . LEU B 2 119 ? 29.59476 30.14719  50.59021  1.000 65.08601  ? 119 LEU L CG  1 
ATOM   2595 C CD1 . LEU B 2 119 ? 29.56075 28.69154  50.15450  1.000 68.81066  ? 119 LEU L CD1 1 
ATOM   2596 C CD2 . LEU B 2 119 ? 30.38944 30.98356  49.60174  1.000 70.62628  ? 119 LEU L CD2 1 
ATOM   2597 N N   . PHE B 2 120 ? 28.27630 28.71521  53.48473  1.000 63.51991  ? 120 PHE L N   1 
ATOM   2598 C CA  . PHE B 2 120 ? 28.85896 28.48737  54.79693  1.000 65.06341  ? 120 PHE L CA  1 
ATOM   2599 C C   . PHE B 2 120 ? 30.33387 28.14487  54.66938  1.000 75.89176  ? 120 PHE L C   1 
ATOM   2600 O O   . PHE B 2 120 ? 30.68836 27.22786  53.91623  1.000 73.89074  ? 120 PHE L O   1 
ATOM   2601 C CB  . PHE B 2 120 ? 28.12536 27.35484  55.52551  1.000 75.66099  ? 120 PHE L CB  1 
ATOM   2602 C CG  . PHE B 2 120 ? 26.77287 27.74478  56.04866  1.000 74.10231  ? 120 PHE L CG  1 
ATOM   2603 C CD1 . PHE B 2 120 ? 26.65502 28.59392  57.13598  1.000 78.28719  ? 120 PHE L CD1 1 
ATOM   2604 C CD2 . PHE B 2 120 ? 25.61926 27.25947  55.45552  1.000 83.57584  ? 120 PHE L CD2 1 
ATOM   2605 C CE1 . PHE B 2 120 ? 25.41161 28.95365  57.62076  1.000 95.68550  ? 120 PHE L CE1 1 
ATOM   2606 C CE2 . PHE B 2 120 ? 24.37266 27.61536  55.93548  1.000 71.52006  ? 120 PHE L CE2 1 
ATOM   2607 C CZ  . PHE B 2 120 ? 24.26894 28.46337  57.01917  1.000 85.41342  ? 120 PHE L CZ  1 
ATOM   2608 N N   . PRO B 2 121 ? 31.21432 28.84823  55.37501  1.000 84.69045  ? 121 PRO L N   1 
ATOM   2609 C CA  . PRO B 2 121 ? 32.63960 28.50702  55.34558  1.000 80.94799  ? 121 PRO L CA  1 
ATOM   2610 C C   . PRO B 2 121 ? 32.90393 27.22474  56.11334  1.000 78.46033  ? 121 PRO L C   1 
ATOM   2611 O O   . PRO B 2 121 ? 32.05705 26.78356  56.90542  1.000 62.26568  ? 121 PRO L O   1 
ATOM   2612 C CB  . PRO B 2 121 ? 33.30017 29.71482  56.02570  1.000 72.27638  ? 121 PRO L CB  1 
ATOM   2613 C CG  . PRO B 2 121 ? 32.25052 30.22183  56.95326  1.000 75.93626  ? 121 PRO L CG  1 
ATOM   2614 C CD  . PRO B 2 121 ? 30.94265 30.01405  56.23434  1.000 79.43335  ? 121 PRO L CD  1 
ATOM   2615 N N   . PRO B 2 122 ? 34.05596 26.58743  55.89477  1.000 85.52177  ? 122 PRO L N   1 
ATOM   2616 C CA  . PRO B 2 122 ? 34.36801 25.35685  56.63275  1.000 79.35620  ? 122 PRO L CA  1 
ATOM   2617 C C   . PRO B 2 122 ? 34.37686 25.59121  58.13630  1.000 90.83607  ? 122 PRO L C   1 
ATOM   2618 O O   . PRO B 2 122 ? 34.83109 26.62935  58.62163  1.000 101.17028 ? 122 PRO L O   1 
ATOM   2619 C CB  . PRO B 2 122 ? 35.75992 24.97883  56.11484  1.000 75.19150  ? 122 PRO L CB  1 
ATOM   2620 C CG  . PRO B 2 122 ? 35.82357 25.58312  54.75541  1.000 83.04373  ? 122 PRO L CG  1 
ATOM   2621 C CD  . PRO B 2 122 ? 35.06196 26.87565  54.85757  1.000 88.64227  ? 122 PRO L CD  1 
ATOM   2622 N N   . SER B 2 123 ? 33.86780 24.60766  58.87222  1.000 97.27919  ? 123 SER L N   1 
ATOM   2623 C CA  . SER B 2 123 ? 33.75557 24.71813  60.31660  1.000 79.02334  ? 123 SER L CA  1 
ATOM   2624 C C   . SER B 2 123 ? 35.11019 24.50314  60.98511  1.000 82.88765  ? 123 SER L C   1 
ATOM   2625 O O   . SER B 2 123 ? 36.05420 23.97564  60.39003  1.000 74.49526  ? 123 SER L O   1 
ATOM   2626 C CB  . SER B 2 123 ? 32.74137 23.70961  60.85651  1.000 77.39858  ? 123 SER L CB  1 
ATOM   2627 O OG  . SER B 2 123 ? 33.15826 22.38012  60.60057  1.000 75.57227  ? 123 SER L OG  1 
ATOM   2628 N N   . SER B 2 124 ? 35.19345 24.93092  62.24742  1.000 94.27491  ? 124 SER L N   1 
ATOM   2629 C CA  . SER B 2 124 ? 36.42163 24.75012  63.01449  1.000 92.81097  ? 124 SER L CA  1 
ATOM   2630 C C   . SER B 2 124 ? 36.71795 23.27352  63.24636  1.000 79.07955  ? 124 SER L C   1 
ATOM   2631 O O   . SER B 2 124 ? 37.87559 22.84510  63.16980  1.000 73.55101  ? 124 SER L O   1 
ATOM   2632 C CB  . SER B 2 124 ? 36.31993 25.49339  64.34654  1.000 90.33478  ? 124 SER L CB  1 
ATOM   2633 O OG  . SER B 2 124 ? 37.49728 25.32530  65.11670  1.000 105.96374 ? 124 SER L OG  1 
ATOM   2634 N N   . GLU B 2 125 ? 35.68520 22.48091  63.54225  1.000 70.48225  ? 125 GLU L N   1 
ATOM   2635 C CA  . GLU B 2 125 ? 35.89410 21.05814  63.79172  1.000 73.39621  ? 125 GLU L CA  1 
ATOM   2636 C C   . GLU B 2 125 ? 36.34974 20.32927  62.53384  1.000 73.74021  ? 125 GLU L C   1 
ATOM   2637 O O   . GLU B 2 125 ? 37.21417 19.44776  62.60171  1.000 83.47040  ? 125 GLU L O   1 
ATOM   2638 C CB  . GLU B 2 125 ? 34.61755 20.42441  64.34042  1.000 87.23001  ? 125 GLU L CB  1 
ATOM   2639 C CG  . GLU B 2 125 ? 34.84362 19.06826  64.98464  1.000 101.76091 ? 125 GLU L CG  1 
ATOM   2640 C CD  . GLU B 2 125 ? 33.55207 18.32066  65.23597  1.000 112.77756 ? 125 GLU L CD  1 
ATOM   2641 O OE1 . GLU B 2 125 ? 32.49503 18.77959  64.75402  1.000 105.11621 ? 125 GLU L OE1 1 
ATOM   2642 O OE2 . GLU B 2 125 ? 33.59203 17.27195  65.91325  1.000 120.03210 ? 125 GLU L OE2 1 
ATOM   2643 N N   . GLU B 2 126 ? 35.77156 20.67004  61.37938  1.000 74.63052  ? 126 GLU L N   1 
ATOM   2644 C CA  . GLU B 2 126 ? 36.15316 19.99698  60.14173  1.000 79.59623  ? 126 GLU L CA  1 
ATOM   2645 C C   . GLU B 2 126 ? 37.60546 20.28204  59.78242  1.000 77.86617  ? 126 GLU L C   1 
ATOM   2646 O O   . GLU B 2 126 ? 38.32390 19.38963  59.31646  1.000 82.33408  ? 126 GLU L O   1 
ATOM   2647 C CB  . GLU B 2 126 ? 35.22602 20.41599  59.00259  1.000 85.48264  ? 126 GLU L CB  1 
ATOM   2648 C CG  . GLU B 2 126 ? 35.42033 19.60287  57.73535  1.000 83.49650  ? 126 GLU L CG  1 
ATOM   2649 C CD  . GLU B 2 126 ? 34.48738 20.02521  56.62254  1.000 85.69569  ? 126 GLU L CD  1 
ATOM   2650 O OE1 . GLU B 2 126 ? 34.05378 21.19666  56.62092  1.000 82.01818  ? 126 GLU L OE1 1 
ATOM   2651 O OE2 . GLU B 2 126 ? 34.18975 19.18399  55.74895  1.000 95.20739  ? 126 GLU L OE2 1 
ATOM   2652 N N   . LEU B 2 127 ? 38.05527 21.52267  59.98777  1.000 74.73660  ? 127 LEU L N   1 
ATOM   2653 C CA  . LEU B 2 127 ? 39.45742 21.84620  59.74777  1.000 79.89504  ? 127 LEU L CA  1 
ATOM   2654 C C   . LEU B 2 127 ? 40.37631 21.06985  60.68199  1.000 96.67461  ? 127 LEU L C   1 
ATOM   2655 O O   . LEU B 2 127 ? 41.53185 20.80128  60.33416  1.000 93.76938  ? 127 LEU L O   1 
ATOM   2656 C CB  . LEU B 2 127 ? 39.68403 23.35012  59.90327  1.000 75.65017  ? 127 LEU L CB  1 
ATOM   2657 C CG  . LEU B 2 127 ? 39.11624 24.23369  58.79056  1.000 87.62477  ? 127 LEU L CG  1 
ATOM   2658 C CD1 . LEU B 2 127 ? 39.16705 25.69996  59.18966  1.000 94.31473  ? 127 LEU L CD1 1 
ATOM   2659 C CD2 . LEU B 2 127 ? 39.86064 24.00302  57.48422  1.000 90.03551  ? 127 LEU L CD2 1 
ATOM   2660 N N   . GLN B 2 128 ? 39.88251 20.69722  61.86547  1.000 100.53967 ? 128 GLN L N   1 
ATOM   2661 C CA  . GLN B 2 128 ? 40.66177 19.89626  62.80124  1.000 85.88434  ? 128 GLN L CA  1 
ATOM   2662 C C   . GLN B 2 128 ? 40.82329 18.45168  62.34766  1.000 84.14152  ? 128 GLN L C   1 
ATOM   2663 O O   . GLN B 2 128 ? 41.66472 17.73757  62.90347  1.000 87.40305  ? 128 GLN L O   1 
ATOM   2664 C CB  . GLN B 2 128 ? 40.01145 19.92673  64.18630  1.000 86.76971  ? 128 GLN L CB  1 
ATOM   2665 C CG  . GLN B 2 128 ? 40.31666 21.17618  64.99357  1.000 99.33364  ? 128 GLN L CG  1 
ATOM   2666 C CD  . GLN B 2 128 ? 39.42227 21.31997  66.20903  1.000 93.96130  ? 128 GLN L CD  1 
ATOM   2667 O OE1 . GLN B 2 128 ? 38.82896 20.34772  66.67604  1.000 84.30077  ? 128 GLN L OE1 1 
ATOM   2668 N NE2 . GLN B 2 128 ? 39.32115 22.53834  66.72867  1.000 80.74855  ? 128 GLN L NE2 1 
ATOM   2669 N N   . ALA B 2 129 ? 40.04528 18.00665  61.36078  1.000 76.87457  ? 129 ALA L N   1 
ATOM   2670 C CA  . ALA B 2 129 ? 40.11344 16.64380  60.84960  1.000 86.53249  ? 129 ALA L CA  1 
ATOM   2671 C C   . ALA B 2 129 ? 40.78339 16.58222  59.47946  1.000 100.55318 ? 129 ALA L C   1 
ATOM   2672 O O   . ALA B 2 129 ? 40.51266 15.67216  58.69158  1.000 95.58784  ? 129 ALA L O   1 
ATOM   2673 C CB  . ALA B 2 129 ? 38.71773 16.02571  60.78888  1.000 86.11553  ? 129 ALA L CB  1 
ATOM   2674 N N   . ASN B 2 130 ? 41.65938 17.54804  59.18884  1.000 99.17150  ? 130 ASN L N   1 
ATOM   2675 C CA  . ASN B 2 130 ? 42.38570 17.61166  57.91843  1.000 92.34269  ? 130 ASN L CA  1 
ATOM   2676 C C   . ASN B 2 130 ? 41.42728 17.63644  56.72929  1.000 106.83326 ? 130 ASN L C   1 
ATOM   2677 O O   . ASN B 2 130 ? 41.66929 17.00619  55.69774  1.000 110.41027 ? 130 ASN L O   1 
ATOM   2678 C CB  . ASN B 2 130 ? 43.38192 16.45652  57.79195  1.000 96.64753  ? 130 ASN L CB  1 
ATOM   2679 C CG  . ASN B 2 130 ? 44.65383 16.86091  57.07507  1.000 133.05441 ? 130 ASN L CG  1 
ATOM   2680 O OD1 . ASN B 2 130 ? 45.22911 17.91302  57.35333  1.000 130.48087 ? 130 ASN L OD1 1 
ATOM   2681 N ND2 . ASN B 2 130 ? 45.09966 16.02516  56.14384  1.000 158.95894 ? 130 ASN L ND2 1 
ATOM   2682 N N   . LYS B 2 131 ? 40.32850 18.37376  56.87508  1.000 111.43859 ? 131 LYS L N   1 
ATOM   2683 C CA  . LYS B 2 131 ? 39.31120 18.46541  55.83978  1.000 97.94579  ? 131 LYS L CA  1 
ATOM   2684 C C   . LYS B 2 131 ? 38.76030 19.88353  55.80219  1.000 95.08888  ? 131 LYS L C   1 
ATOM   2685 O O   . LYS B 2 131 ? 38.82885 20.62552  56.78472  1.000 102.46935 ? 131 LYS L O   1 
ATOM   2686 C CB  . LYS B 2 131 ? 38.17896 17.45689  56.07759  1.000 97.69124  ? 131 LYS L CB  1 
ATOM   2687 C CG  . LYS B 2 131 ? 38.42553 16.09027  55.45487  1.000 114.24622 ? 131 LYS L CG  1 
ATOM   2688 C CD  . LYS B 2 131 ? 37.33274 15.09331  55.82156  1.000 129.01801 ? 131 LYS L CD  1 
ATOM   2689 C CE  . LYS B 2 131 ? 36.80374 15.32703  57.22961  1.000 121.57068 ? 131 LYS L CE  1 
ATOM   2690 N NZ  . LYS B 2 131 ? 35.98944 14.17965  57.71766  1.000 115.40224 ? 131 LYS L NZ  1 
ATOM   2691 N N   . ALA B 2 132 ? 38.21155 20.25463  54.64795  1.000 88.52453  ? 132 ALA L N   1 
ATOM   2692 C CA  . ALA B 2 132 ? 37.62300 21.58066  54.47405  1.000 90.50793  ? 132 ALA L CA  1 
ATOM   2693 C C   . ALA B 2 132 ? 36.58212 21.50228  53.37088  1.000 91.29504  ? 132 ALA L C   1 
ATOM   2694 O O   . ALA B 2 132 ? 36.90229 21.10195  52.24704  1.000 86.74500  ? 132 ALA L O   1 
ATOM   2695 C CB  . ALA B 2 132 ? 38.69396 22.61839  54.13831  1.000 96.39754  ? 132 ALA L CB  1 
ATOM   2696 N N   . THR B 2 133 ? 35.34513 21.87892  53.68609  1.000 86.27372  ? 133 THR L N   1 
ATOM   2697 C CA  . THR B 2 133 ? 34.25180 21.81925  52.72852  1.000 80.03566  ? 133 THR L CA  1 
ATOM   2698 C C   . THR B 2 133 ? 33.44857 23.10883  52.79186  1.000 74.82158  ? 133 THR L C   1 
ATOM   2699 O O   . THR B 2 133 ? 33.15506 23.61443  53.87883  1.000 71.14180  ? 133 THR L O   1 
ATOM   2700 C CB  . THR B 2 133 ? 33.33296 20.61883  52.99978  1.000 72.94743  ? 133 THR L CB  1 
ATOM   2701 O OG1 . THR B 2 133 ? 34.11704 19.42183  53.07750  1.000 78.55603  ? 133 THR L OG1 1 
ATOM   2702 C CG2 . THR B 2 133 ? 32.30472 20.46915  51.88979  1.000 85.80070  ? 133 THR L CG2 1 
ATOM   2703 N N   . LEU B 2 134 ? 33.09847 23.63519  51.62209  1.000 76.69631  ? 134 LEU L N   1 
ATOM   2704 C CA  . LEU B 2 134 ? 32.23446 24.80173  51.50897  1.000 69.89040  ? 134 LEU L CA  1 
ATOM   2705 C C   . LEU B 2 134 ? 30.85036 24.34984  51.06569  1.000 64.37501  ? 134 LEU L C   1 
ATOM   2706 O O   . LEU B 2 134 ? 30.71833 23.62308  50.07608  1.000 76.58074  ? 134 LEU L O   1 
ATOM   2707 C CB  . LEU B 2 134 ? 32.80519 25.81565  50.51656  1.000 62.09656  ? 134 LEU L CB  1 
ATOM   2708 C CG  . LEU B 2 134 ? 33.82112 26.81886  51.06567  1.000 74.75391  ? 134 LEU L CG  1 
ATOM   2709 C CD1 . LEU B 2 134 ? 35.21653 26.21656  51.10032  1.000 71.07379  ? 134 LEU L CD1 1 
ATOM   2710 C CD2 . LEU B 2 134 ? 33.80479 28.09735  50.24364  1.000 70.62657  ? 134 LEU L CD2 1 
ATOM   2711 N N   . VAL B 2 135 ? 29.82584 24.77679  51.79754  1.000 68.98633  ? 135 VAL L N   1 
ATOM   2712 C CA  . VAL B 2 135 ? 28.44902 24.36662  51.54699  1.000 63.83945  ? 135 VAL L CA  1 
ATOM   2713 C C   . VAL B 2 135 ? 27.69436 25.55604  50.97156  1.000 70.00111  ? 135 VAL L C   1 
ATOM   2714 O O   . VAL B 2 135 ? 27.53391 26.58389  51.64160  1.000 74.30992  ? 135 VAL L O   1 
ATOM   2715 C CB  . VAL B 2 135 ? 27.77007 23.84891  52.82421  1.000 64.94323  ? 135 VAL L CB  1 
ATOM   2716 C CG1 . VAL B 2 135 ? 26.35483 23.38206  52.52106  1.000 62.66156  ? 135 VAL L CG1 1 
ATOM   2717 C CG2 . VAL B 2 135 ? 28.58760 22.72462  53.44127  1.000 68.56249  ? 135 VAL L CG2 1 
ATOM   2718 N N   . CYS B 2 136 ? 27.23008 25.41479  49.73366  1.000 69.97952  ? 136 CYS L N   1 
ATOM   2719 C CA  . CYS B 2 136 ? 26.41383 26.42131  49.06768  1.000 71.01272  ? 136 CYS L CA  1 
ATOM   2720 C C   . CYS B 2 136 ? 25.00950 25.85715  48.90350  1.000 68.81966  ? 136 CYS L C   1 
ATOM   2721 O O   . CYS B 2 136 ? 24.82483 24.82882  48.24357  1.000 70.47029  ? 136 CYS L O   1 
ATOM   2722 C CB  . CYS B 2 136 ? 27.01185 26.80297  47.71268  1.000 68.63891  ? 136 CYS L CB  1 
ATOM   2723 S SG  . CYS B 2 136 ? 26.45332 28.39183  47.04989  1.000 70.37501  ? 136 CYS L SG  1 
ATOM   2724 N N   . LEU B 2 137 ? 24.02762 26.52431  49.50196  1.000 66.10904  ? 137 LEU L N   1 
ATOM   2725 C CA  . LEU B 2 137 ? 22.64911 26.05446  49.51199  1.000 64.84079  ? 137 LEU L CA  1 
ATOM   2726 C C   . LEU B 2 137 ? 21.77793 26.99676  48.69380  1.000 62.94269  ? 137 LEU L C   1 
ATOM   2727 O O   . LEU B 2 137 ? 21.78885 28.21208  48.91691  1.000 64.16934  ? 137 LEU L O   1 
ATOM   2728 C CB  . LEU B 2 137 ? 22.11961 25.94520  50.94380  1.000 70.53836  ? 137 LEU L CB  1 
ATOM   2729 C CG  . LEU B 2 137 ? 22.88994 24.99765  51.86738  1.000 56.69141  ? 137 LEU L CG  1 
ATOM   2730 C CD1 . LEU B 2 137 ? 22.39884 25.11986  53.30046  1.000 55.71549  ? 137 LEU L CD1 1 
ATOM   2731 C CD2 . LEU B 2 137 ? 22.77824 23.56137  51.38049  1.000 66.61320  ? 137 LEU L CD2 1 
ATOM   2732 N N   . ILE B 2 138 ? 21.02757 26.43071  47.75134  1.000 69.55820  ? 138 ILE L N   1 
ATOM   2733 C CA  . ILE B 2 138 ? 20.14201 27.17960  46.86793  1.000 67.48668  ? 138 ILE L CA  1 
ATOM   2734 C C   . ILE B 2 138 ? 18.71673 26.71608  47.12709  1.000 69.24203  ? 138 ILE L C   1 
ATOM   2735 O O   . ILE B 2 138 ? 18.45358 25.50924  47.18132  1.000 75.24835  ? 138 ILE L O   1 
ATOM   2736 C CB  . ILE B 2 138 ? 20.51711 26.98336  45.38800  1.000 53.86639  ? 138 ILE L CB  1 
ATOM   2737 C CG1 . ILE B 2 138 ? 22.03632 26.98955  45.21735  1.000 47.75109  ? 138 ILE L CG1 1 
ATOM   2738 C CG2 . ILE B 2 138 ? 19.87877 28.06236  44.52997  1.000 64.43513  ? 138 ILE L CG2 1 
ATOM   2739 C CD1 . ILE B 2 138 ? 22.49724 26.42213  43.89873  1.000 62.53786  ? 138 ILE L CD1 1 
ATOM   2740 N N   . SER B 2 139 ? 17.80084 27.66877  47.28657  1.000 72.47162  ? 139 SER L N   1 
ATOM   2741 C CA  . SER B 2 139 ? 16.42306 27.33358  47.61152  1.000 73.91577  ? 139 SER L CA  1 
ATOM   2742 C C   . SER B 2 139 ? 15.48773 28.39650  47.05591  1.000 74.80045  ? 139 SER L C   1 
ATOM   2743 O O   . SER B 2 139 ? 15.89855 29.51963  46.75145  1.000 81.22794  ? 139 SER L O   1 
ATOM   2744 C CB  . SER B 2 139 ? 16.22384 27.19480  49.12521  1.000 84.26138  ? 139 SER L CB  1 
ATOM   2745 O OG  . SER B 2 139 ? 16.24712 28.46341  49.75652  1.000 99.40601  ? 139 SER L OG  1 
ATOM   2746 N N   . ASP B 2 140 ? 14.21515 28.01433  46.92677  1.000 73.17761  ? 140 ASP L N   1 
ATOM   2747 C CA  . ASP B 2 140 ? 13.13509 28.92506  46.54325  1.000 75.52375  ? 140 ASP L CA  1 
ATOM   2748 C C   . ASP B 2 140 ? 13.39734 29.58072  45.18770  1.000 71.46565  ? 140 ASP L C   1 
ATOM   2749 O O   . ASP B 2 140 ? 13.30201 30.79976  45.03312  1.000 70.44171  ? 140 ASP L O   1 
ATOM   2750 C CB  . ASP B 2 140 ? 12.90312 29.98337  47.62504  1.000 93.56011  ? 140 ASP L CB  1 
ATOM   2751 C CG  . ASP B 2 140 ? 12.17944 29.43047  48.83558  1.000 92.04928  ? 140 ASP L CG  1 
ATOM   2752 O OD1 . ASP B 2 140 ? 12.01560 28.19506  48.91939  1.000 93.24504  ? 140 ASP L OD1 1 
ATOM   2753 O OD2 . ASP B 2 140 ? 11.77312 30.23240  49.70258  1.000 95.63089  ? 140 ASP L OD2 1 
ATOM   2754 N N   . PHE B 2 141 ? 13.72368 28.75814  44.19414  1.000 76.95339  ? 141 PHE L N   1 
ATOM   2755 C CA  . PHE B 2 141 ? 13.87281 29.21980  42.82151  1.000 79.85463  ? 141 PHE L CA  1 
ATOM   2756 C C   . PHE B 2 141 ? 12.96308 28.41161  41.90793  1.000 77.46858  ? 141 PHE L C   1 
ATOM   2757 O O   . PHE B 2 141 ? 12.75130 27.21398  42.12410  1.000 75.41650  ? 141 PHE L O   1 
ATOM   2758 C CB  . PHE B 2 141 ? 15.33577 29.13892  42.34630  1.000 78.48577  ? 141 PHE L CB  1 
ATOM   2759 C CG  . PHE B 2 141 ? 15.88260 27.74036  42.24837  1.000 67.58708  ? 141 PHE L CG  1 
ATOM   2760 C CD1 . PHE B 2 141 ? 15.73598 26.99854  41.08676  1.000 66.44864  ? 141 PHE L CD1 1 
ATOM   2761 C CD2 . PHE B 2 141 ? 16.57448 27.18117  43.30912  1.000 70.25487  ? 141 PHE L CD2 1 
ATOM   2762 C CE1 . PHE B 2 141 ? 16.24826 25.71887  40.99528  1.000 71.70780  ? 141 PHE L CE1 1 
ATOM   2763 C CE2 . PHE B 2 141 ? 17.09043 25.90166  43.22238  1.000 73.04734  ? 141 PHE L CE2 1 
ATOM   2764 C CZ  . PHE B 2 141 ? 16.92568 25.16974  42.06463  1.000 80.38769  ? 141 PHE L CZ  1 
ATOM   2765 N N   . TYR B 2 142 ? 12.42091 29.08222  40.88957  1.000 74.40790  ? 142 TYR L N   1 
ATOM   2766 C CA  . TYR B 2 142 ? 11.47109 28.49940  39.96318  1.000 71.25290  ? 142 TYR L CA  1 
ATOM   2767 C C   . TYR B 2 142 ? 11.61682 29.24517  38.64349  1.000 79.46517  ? 142 TYR L C   1 
ATOM   2768 O O   . TYR B 2 142 ? 11.61847 30.48687  38.65075  1.000 85.39703  ? 142 TYR L O   1 
ATOM   2769 C CB  . TYR B 2 142 ? 10.03520 28.60718  40.47831  1.000 78.60131  ? 142 TYR L CB  1 
ATOM   2770 C CG  . TYR B 2 142 ? 9.00131  27.91744  39.61708  1.000 69.70813  ? 142 TYR L CG  1 
ATOM   2771 C CD1 . TYR B 2 142 ? 8.72941  26.56493  39.77368  1.000 59.27812  ? 142 TYR L CD1 1 
ATOM   2772 C CD2 . TYR B 2 142 ? 8.28916  28.62182  38.65464  1.000 77.17261  ? 142 TYR L CD2 1 
ATOM   2773 C CE1 . TYR B 2 142 ? 7.78116  25.93164  38.99254  1.000 65.52292  ? 142 TYR L CE1 1 
ATOM   2774 C CE2 . TYR B 2 142 ? 7.33985  27.99721  37.86784  1.000 73.56841  ? 142 TYR L CE2 1 
ATOM   2775 C CZ  . TYR B 2 142 ? 7.08976  26.65259  38.04111  1.000 78.58035  ? 142 TYR L CZ  1 
ATOM   2776 O OH  . TYR B 2 142 ? 6.14500  26.02728  37.26008  1.000 78.48852  ? 142 TYR L OH  1 
ATOM   2777 N N   . PRO B 2 143 ? 11.73495 28.54202  37.50557  1.000 83.79456  ? 143 PRO L N   1 
ATOM   2778 C CA  . PRO B 2 143 ? 11.73115 27.07898  37.31765  1.000 83.33035  ? 143 PRO L CA  1 
ATOM   2779 C C   . PRO B 2 143 ? 12.94891 26.38027  37.91626  1.000 85.55131  ? 143 PRO L C   1 
ATOM   2780 O O   . PRO B 2 143 ? 13.94985 27.01741  38.23492  1.000 82.85800  ? 143 PRO L O   1 
ATOM   2781 C CB  . PRO B 2 143 ? 11.71021 26.93465  35.78699  1.000 61.39899  ? 143 PRO L CB  1 
ATOM   2782 C CG  . PRO B 2 143 ? 11.04534 28.18766  35.31287  1.000 65.53966  ? 143 PRO L CG  1 
ATOM   2783 C CD  . PRO B 2 143 ? 11.62493 29.23759  36.21255  1.000 69.24613  ? 143 PRO L CD  1 
ATOM   2784 N N   . GLY B 2 144 ? 12.88084 25.06043  38.07561  1.000 72.30367  ? 144 GLY L N   1 
ATOM   2785 C CA  . GLY B 2 144 ? 13.94920 24.31222  38.70762  1.000 67.22047  ? 144 GLY L CA  1 
ATOM   2786 C C   . GLY B 2 144 ? 15.12340 24.00601  37.80265  1.000 64.70978  ? 144 GLY L C   1 
ATOM   2787 O O   . GLY B 2 144 ? 15.36728 22.84436  37.46389  1.000 81.46783  ? 144 GLY L O   1 
ATOM   2788 N N   . ALA B 2 145 ? 15.86297 25.04058  37.40925  1.000 63.37636  ? 145 ALA L N   1 
ATOM   2789 C CA  . ALA B 2 145 ? 17.04016 24.86738  36.56196  1.000 59.14363  ? 145 ALA L CA  1 
ATOM   2790 C C   . ALA B 2 145 ? 18.01229 25.99512  36.87536  1.000 51.59013  ? 145 ALA L C   1 
ATOM   2791 O O   . ALA B 2 145 ? 17.71579 27.16273  36.60568  1.000 62.40179  ? 145 ALA L O   1 
ATOM   2792 C CB  . ALA B 2 145 ? 16.66087 24.86037  35.08375  1.000 78.45792  ? 145 ALA L CB  1 
ATOM   2793 N N   . VAL B 2 146 ? 19.16555 25.64830  37.44849  1.000 45.98421  ? 146 VAL L N   1 
ATOM   2794 C CA  . VAL B 2 146 ? 20.17660 26.62432  37.83137  1.000 58.61488  ? 146 VAL L CA  1 
ATOM   2795 C C   . VAL B 2 146 ? 21.54529 26.11744  37.39965  1.000 60.55832  ? 146 VAL L C   1 
ATOM   2796 O O   . VAL B 2 146 ? 21.74788 24.92516  37.16007  1.000 62.52374  ? 146 VAL L O   1 
ATOM   2797 C CB  . VAL B 2 146 ? 20.17350 26.91026  39.35151  1.000 82.16087  ? 146 VAL L CB  1 
ATOM   2798 C CG1 . VAL B 2 146 ? 18.98770 27.78234  39.72949  1.000 72.17840  ? 146 VAL L CG1 1 
ATOM   2799 C CG2 . VAL B 2 146 ? 20.16048 25.60832  40.14043  1.000 62.17854  ? 146 VAL L CG2 1 
ATOM   2800 N N   . THR B 2 147 ? 22.48942 27.04961  37.29649  1.000 61.04847  ? 147 THR L N   1 
ATOM   2801 C CA  . THR B 2 147 ? 23.88462 26.74189  37.01282  1.000 72.81144  ? 147 THR L CA  1 
ATOM   2802 C C   . THR B 2 147 ? 24.74448 27.30083  38.13709  1.000 81.76056  ? 147 THR L C   1 
ATOM   2803 O O   . THR B 2 147 ? 24.58562 28.46316  38.52523  1.000 84.49595  ? 147 THR L O   1 
ATOM   2804 C CB  . THR B 2 147 ? 24.32932 27.32424  35.66602  1.000 76.14863  ? 147 THR L CB  1 
ATOM   2805 O OG1 . THR B 2 147 ? 24.67467 28.70502  35.82957  1.000 82.47875  ? 147 THR L OG1 1 
ATOM   2806 C CG2 . THR B 2 147 ? 23.21844 27.20319  34.63068  1.000 84.59167  ? 147 THR L CG2 1 
ATOM   2807 N N   . VAL B 2 148 ? 25.64926 26.47541  38.65734  1.000 70.07260  ? 148 VAL L N   1 
ATOM   2808 C CA  . VAL B 2 148 ? 26.50225 26.83799  39.78300  1.000 65.84787  ? 148 VAL L CA  1 
ATOM   2809 C C   . VAL B 2 148 ? 27.94758 26.85610  39.30840  1.000 68.62336  ? 148 VAL L C   1 
ATOM   2810 O O   . VAL B 2 148 ? 28.41550 25.89221  38.69112  1.000 85.69528  ? 148 VAL L O   1 
ATOM   2811 C CB  . VAL B 2 148 ? 26.32916 25.86547  40.96432  1.000 70.87117  ? 148 VAL L CB  1 
ATOM   2812 C CG1 . VAL B 2 148 ? 27.01507 26.41147  42.20774  1.000 59.20598  ? 148 VAL L CG1 1 
ATOM   2813 C CG2 . VAL B 2 148 ? 24.85427 25.60942  41.22901  1.000 71.87661  ? 148 VAL L CG2 1 
ATOM   2814 N N   . ALA B 2 149 ? 28.64967 27.95112  39.59454  1.000 62.56527  ? 149 ALA L N   1 
ATOM   2815 C CA  . ALA B 2 149 ? 30.05720 28.09962  39.24417  1.000 70.04005  ? 149 ALA L CA  1 
ATOM   2816 C C   . ALA B 2 149 ? 30.80200 28.66348  40.44345  1.000 74.17185  ? 149 ALA L C   1 
ATOM   2817 O O   . ALA B 2 149 ? 30.45832 29.74193  40.93760  1.000 77.59052  ? 149 ALA L O   1 
ATOM   2818 C CB  . ALA B 2 149 ? 30.23235 29.00869  38.02462  1.000 82.01207  ? 149 ALA L CB  1 
ATOM   2819 N N   . TRP B 2 150 ? 31.81793 27.94063  40.90506  1.000 87.48376  ? 150 TRP L N   1 
ATOM   2820 C CA  . TRP B 2 150 ? 32.61382 28.36636  42.04607  1.000 73.93690  ? 150 TRP L CA  1 
ATOM   2821 C C   . TRP B 2 150 ? 33.80740 29.19327  41.58655  1.000 75.95228  ? 150 TRP L C   1 
ATOM   2822 O O   . TRP B 2 150 ? 34.38041 28.95577  40.52000  1.000 103.98530 ? 150 TRP L O   1 
ATOM   2823 C CB  . TRP B 2 150 ? 33.10205 27.16039  42.84975  1.000 77.65069  ? 150 TRP L CB  1 
ATOM   2824 C CG  . TRP B 2 150 ? 32.01664 26.44608  43.59024  1.000 75.25814  ? 150 TRP L CG  1 
ATOM   2825 C CD1 . TRP B 2 150 ? 31.11802 25.55960  43.07335  1.000 70.92328  ? 150 TRP L CD1 1 
ATOM   2826 C CD2 . TRP B 2 150 ? 31.71435 26.55645  44.98584  1.000 78.46226  ? 150 TRP L CD2 1 
ATOM   2827 N NE1 . TRP B 2 150 ? 30.27519 25.11002  44.06033  1.000 73.45104  ? 150 TRP L NE1 1 
ATOM   2828 C CE2 . TRP B 2 150 ? 30.62031 25.70736  45.24415  1.000 85.25302  ? 150 TRP L CE2 1 
ATOM   2829 C CE3 . TRP B 2 150 ? 32.26176 27.29161  46.04181  1.000 77.34146  ? 150 TRP L CE3 1 
ATOM   2830 C CZ2 . TRP B 2 150 ? 30.06454 25.57183  46.51447  1.000 79.07116  ? 150 TRP L CZ2 1 
ATOM   2831 C CZ3 . TRP B 2 150 ? 31.70854 27.15560  47.30227  1.000 77.64835  ? 150 TRP L CZ3 1 
ATOM   2832 C CH2 . TRP B 2 150 ? 30.62087 26.30329  47.52753  1.000 74.27652  ? 150 TRP L CH2 1 
ATOM   2833 N N   . LYS B 2 151 ? 34.17907 30.17247  42.40776  1.000 66.41108  ? 151 LYS L N   1 
ATOM   2834 C CA  . LYS B 2 151 ? 35.30987 31.04181  42.12371  1.000 81.29294  ? 151 LYS L CA  1 
ATOM   2835 C C   . LYS B 2 151 ? 36.19239 31.15622  43.35793  1.000 93.99095  ? 151 LYS L C   1 
ATOM   2836 O O   . LYS B 2 151 ? 35.70939 31.12889  44.49336  1.000 87.75411  ? 151 LYS L O   1 
ATOM   2837 C CB  . LYS B 2 151 ? 34.85152 32.43955  41.67911  1.000 74.72982  ? 151 LYS L CB  1 
ATOM   2838 C CG  . LYS B 2 151 ? 33.88247 32.43343  40.50661  1.000 101.41739 ? 151 LYS L CG  1 
ATOM   2839 C CD  . LYS B 2 151 ? 34.36128 33.33575  39.38222  1.000 94.68081  ? 151 LYS L CD  1 
ATOM   2840 C CE  . LYS B 2 151 ? 33.51814 33.14786  38.13165  1.000 75.81998  ? 151 LYS L CE  1 
ATOM   2841 N NZ  . LYS B 2 151 ? 33.68143 34.27901  37.17723  1.000 94.18844  ? 151 LYS L NZ  1 
ATOM   2842 N N   . ALA B 2 152 ? 37.49658 31.28388  43.12125  1.000 101.29405 ? 152 ALA L N   1 
ATOM   2843 C CA  . ALA B 2 152 ? 38.48526 31.45249  44.18207  1.000 89.22405  ? 152 ALA L CA  1 
ATOM   2844 C C   . ALA B 2 152 ? 39.40867 32.59500  43.78550  1.000 91.82165  ? 152 ALA L C   1 
ATOM   2845 O O   . ALA B 2 152 ? 40.27059 32.42365  42.91686  1.000 101.51765 ? 152 ALA L O   1 
ATOM   2846 C CB  . ALA B 2 152 ? 39.27549 30.16494  44.41536  1.000 81.39807  ? 152 ALA L CB  1 
ATOM   2847 N N   . ASP B 2 153 ? 39.23092 33.75185  44.42464  1.000 84.29067  ? 153 ASP L N   1 
ATOM   2848 C CA  . ASP B 2 153 ? 39.97472 34.96629  44.08986  1.000 92.24132  ? 153 ASP L CA  1 
ATOM   2849 C C   . ASP B 2 153 ? 39.81949 35.30535  42.60811  1.000 111.73383 ? 153 ASP L C   1 
ATOM   2850 O O   . ASP B 2 153 ? 40.79208 35.56404  41.89513  1.000 121.96656 ? 153 ASP L O   1 
ATOM   2851 C CB  . ASP B 2 153 ? 41.45002 34.83337  44.47530  1.000 97.94450  ? 153 ASP L CB  1 
ATOM   2852 C CG  . ASP B 2 153 ? 41.65219 34.69427  45.97230  1.000 110.65353 ? 153 ASP L CG  1 
ATOM   2853 O OD1 . ASP B 2 153 ? 40.66338 34.82801  46.72354  1.000 110.08910 ? 153 ASP L OD1 1 
ATOM   2854 O OD2 . ASP B 2 153 ? 42.80061 34.44942  46.39827  1.000 111.69375 ? 153 ASP L OD2 1 
ATOM   2855 N N   . SER B 2 154 ? 38.56825 35.28109  42.14543  1.000 115.11773 ? 154 SER L N   1 
ATOM   2856 C CA  . SER B 2 154 ? 38.14064 35.56078  40.77605  1.000 99.52322  ? 154 SER L CA  1 
ATOM   2857 C C   . SER B 2 154 ? 38.59362 34.49912  39.78028  1.000 93.62100  ? 154 SER L C   1 
ATOM   2858 O O   . SER B 2 154 ? 38.32243 34.64249  38.58167  1.000 102.34384 ? 154 SER L O   1 
ATOM   2859 C CB  . SER B 2 154 ? 38.61034 36.93800  40.28266  1.000 92.30633  ? 154 SER L CB  1 
ATOM   2860 O OG  . SER B 2 154 ? 39.82509 36.83346  39.56088  1.000 100.67157 ? 154 SER L OG  1 
ATOM   2861 N N   . SER B 2 155 ? 39.26942 33.44200  40.22642  1.000 88.64205  ? 155 SER L N   1 
ATOM   2862 C CA  . SER B 2 155 ? 39.69655 32.37317  39.33292  1.000 97.36759  ? 155 SER L CA  1 
ATOM   2863 C C   . SER B 2 155 ? 38.66655 31.25251  39.34842  1.000 101.11736 ? 155 SER L C   1 
ATOM   2864 O O   . SER B 2 155 ? 38.35639 30.72989  40.42789  1.000 104.14932 ? 155 SER L O   1 
ATOM   2865 C CB  . SER B 2 155 ? 41.05543 31.83514  39.74741  1.000 93.83673  ? 155 SER L CB  1 
ATOM   2866 O OG  . SER B 2 155 ? 41.91138 32.88153  40.17130  1.000 106.72854 ? 155 SER L OG  1 
ATOM   2867 N N   . PRO B 2 156 ? 38.10354 30.86799  38.20290  1.000 84.39465  ? 156 PRO L N   1 
ATOM   2868 C CA  . PRO B 2 156 ? 37.13468 29.76498  38.19242  1.000 86.30184  ? 156 PRO L CA  1 
ATOM   2869 C C   . PRO B 2 156 ? 37.75605 28.47257  38.70197  1.000 95.67444  ? 156 PRO L C   1 
ATOM   2870 O O   . PRO B 2 156 ? 38.91493 28.16246  38.41820  1.000 98.04903  ? 156 PRO L O   1 
ATOM   2871 C CB  . PRO B 2 156 ? 36.73926 29.65596  36.71541  1.000 83.39985  ? 156 PRO L CB  1 
ATOM   2872 C CG  . PRO B 2 156 ? 37.02896 31.01029  36.14892  1.000 106.67799 ? 156 PRO L CG  1 
ATOM   2873 C CD  . PRO B 2 156 ? 38.25404 31.48368  36.87426  1.000 91.37531  ? 156 PRO L CD  1 
ATOM   2874 N N   . VAL B 2 157 ? 36.96680 27.71636  39.46175  1.000 97.29628  ? 157 VAL L N   1 
ATOM   2875 C CA  . VAL B 2 157 ? 37.40697 26.46600  40.06789  1.000 84.95166  ? 157 VAL L CA  1 
ATOM   2876 C C   . VAL B 2 157 ? 36.39613 25.38237  39.72171  1.000 90.04660  ? 157 VAL L C   1 
ATOM   2877 O O   . VAL B 2 157 ? 35.19176 25.56040  39.93595  1.000 85.14132  ? 157 VAL L O   1 
ATOM   2878 C CB  . VAL B 2 157 ? 37.56279 26.59747  41.59566  1.000 80.48198  ? 157 VAL L CB  1 
ATOM   2879 C CG1 . VAL B 2 157 ? 37.55626 25.22666  42.25691  1.000 89.89828  ? 157 VAL L CG1 1 
ATOM   2880 C CG2 . VAL B 2 157 ? 38.83721 27.35520  41.93482  1.000 81.09389  ? 157 VAL L CG2 1 
ATOM   2881 N N   . LYS B 2 158 ? 36.88503 24.26303  39.18530  1.000 93.35952  ? 158 LYS L N   1 
ATOM   2882 C CA  . LYS B 2 158 ? 36.03637 23.13202  38.82921  1.000 95.58244  ? 158 LYS L CA  1 
ATOM   2883 C C   . LYS B 2 158 ? 36.48109 21.83415  39.49188  1.000 90.88051  ? 158 LYS L C   1 
ATOM   2884 O O   . LYS B 2 158 ? 35.96214 20.76568  39.14684  1.000 85.14175  ? 158 LYS L O   1 
ATOM   2885 C CB  . LYS B 2 158 ? 35.99677 22.95176  37.30825  1.000 101.17561 ? 158 LYS L CB  1 
ATOM   2886 C CG  . LYS B 2 158 ? 34.71844 23.45238  36.65549  1.000 104.39299 ? 158 LYS L CG  1 
ATOM   2887 C CD  . LYS B 2 158 ? 34.83631 23.45656  35.13951  1.000 116.51253 ? 158 LYS L CD  1 
ATOM   2888 C CE  . LYS B 2 158 ? 33.47080 23.56952  34.48009  1.000 119.74016 ? 158 LYS L CE  1 
ATOM   2889 N NZ  . LYS B 2 158 ? 33.01589 22.27024  33.91296  1.000 124.21561 ? 158 LYS L NZ  1 
ATOM   2890 N N   . ALA B 2 159 ? 37.41965 21.89439  40.43172  1.000 89.81650  ? 159 ALA L N   1 
ATOM   2891 C CA  . ALA B 2 159 ? 37.94080 20.70918  41.09842  1.000 93.72644  ? 159 ALA L CA  1 
ATOM   2892 C C   . ALA B 2 159 ? 37.22526 20.51043  42.42762  1.000 101.10856 ? 159 ALA L C   1 
ATOM   2893 O O   . ALA B 2 159 ? 37.19621 21.41879  43.26464  1.000 103.45937 ? 159 ALA L O   1 
ATOM   2894 C CB  . ALA B 2 159 ? 39.44932 20.82804  41.32125  1.000 76.51261  ? 159 ALA L CB  1 
ATOM   2895 N N   . GLY B 2 160 ? 36.65330 19.32322  42.61752  1.000 100.83376 ? 160 GLY L N   1 
ATOM   2896 C CA  . GLY B 2 160 ? 35.96179 19.01490  43.85292  1.000 110.77569 ? 160 GLY L CA  1 
ATOM   2897 C C   . GLY B 2 160 ? 34.57182 19.59198  43.97481  1.000 102.32112 ? 160 GLY L C   1 
ATOM   2898 O O   . GLY B 2 160 ? 34.03834 19.65958  45.08666  1.000 95.33110  ? 160 GLY L O   1 
ATOM   2899 N N   . VAL B 2 161 ? 33.96512 20.01089  42.86907  1.000 87.19559  ? 161 VAL L N   1 
ATOM   2900 C CA  . VAL B 2 161 ? 32.63498 20.60837  42.88907  1.000 70.52358  ? 161 VAL L CA  1 
ATOM   2901 C C   . VAL B 2 161 ? 31.60139 19.51019  42.67418  1.000 83.44552  ? 161 VAL L C   1 
ATOM   2902 O O   . VAL B 2 161 ? 31.65656 18.77778  41.68027  1.000 97.96314  ? 161 VAL L O   1 
ATOM   2903 C CB  . VAL B 2 161 ? 32.50104 21.70530  41.82280  1.000 74.46457  ? 161 VAL L CB  1 
ATOM   2904 C CG1 . VAL B 2 161 ? 31.09493 22.28368  41.83476  1.000 81.33164  ? 161 VAL L CG1 1 
ATOM   2905 C CG2 . VAL B 2 161 ? 33.53544 22.79599  42.04794  1.000 66.45479  ? 161 VAL L CG2 1 
ATOM   2906 N N   . GLU B 2 162 ? 30.65921 19.39578  43.60750  1.000 92.66189  ? 162 GLU L N   1 
ATOM   2907 C CA  . GLU B 2 162 ? 29.55048 18.45796  43.50848  1.000 88.32440  ? 162 GLU L CA  1 
ATOM   2908 C C   . GLU B 2 162 ? 28.25099 19.21356  43.73750  1.000 77.07474  ? 162 GLU L C   1 
ATOM   2909 O O   . GLU B 2 162 ? 28.15983 20.03805  44.65119  1.000 82.10463  ? 162 GLU L O   1 
ATOM   2910 C CB  . GLU B 2 162 ? 29.68621 17.31860  44.52737  1.000 93.25224  ? 162 GLU L CB  1 
ATOM   2911 C CG  . GLU B 2 162 ? 30.95235 16.49047  44.37159  1.000 111.00860 ? 162 GLU L CG  1 
ATOM   2912 C CD  . GLU B 2 162 ? 30.75507 15.28315  43.47528  1.000 125.62163 ? 162 GLU L CD  1 
ATOM   2913 O OE1 . GLU B 2 162 ? 29.60444 14.81242  43.35246  1.000 122.12259 ? 162 GLU L OE1 1 
ATOM   2914 O OE2 . GLU B 2 162 ? 31.75144 14.80440  42.89343  1.000 122.89532 ? 162 GLU L OE2 1 
ATOM   2915 N N   . THR B 2 163 ? 27.24642 18.93203  42.90981  1.000 75.91776  ? 163 THR L N   1 
ATOM   2916 C CA  . THR B 2 163 ? 25.99083 19.66998  42.95897  1.000 75.29071  ? 163 THR L CA  1 
ATOM   2917 C C   . THR B 2 163 ? 24.81765 18.71528  42.80057  1.000 68.20819  ? 163 THR L C   1 
ATOM   2918 O O   . THR B 2 163 ? 24.80782 17.88728  41.88511  1.000 68.58327  ? 163 THR L O   1 
ATOM   2919 C CB  . THR B 2 163 ? 25.94298 20.74559  41.86536  1.000 68.23372  ? 163 THR L CB  1 
ATOM   2920 O OG1 . THR B 2 163 ? 27.03060 21.66124  42.04496  1.000 62.09897  ? 163 THR L OG1 1 
ATOM   2921 C CG2 . THR B 2 163 ? 24.63171 21.51333  41.92582  1.000 70.85910  ? 163 THR L CG2 1 
ATOM   2922 N N   . THR B 2 164 ? 23.83546 18.83330  43.69164  1.000 67.85966  ? 164 THR L N   1 
ATOM   2923 C CA  . THR B 2 164 ? 22.59659 18.08341  43.54496  1.000 74.65868  ? 164 THR L CA  1 
ATOM   2924 C C   . THR B 2 164 ? 21.75258 18.65591  42.41330  1.000 66.45384  ? 164 THR L C   1 
ATOM   2925 O O   . THR B 2 164 ? 21.77647 19.85730  42.13356  1.000 74.05808  ? 164 THR L O   1 
ATOM   2926 C CB  . THR B 2 164 ? 21.78120 18.10892  44.84030  1.000 63.10471  ? 164 THR L CB  1 
ATOM   2927 O OG1 . THR B 2 164 ? 21.66463 19.45748  45.31250  1.000 76.02518  ? 164 THR L OG1 1 
ATOM   2928 C CG2 . THR B 2 164 ? 22.42308 17.24699  45.90760  1.000 65.30732  ? 164 THR L CG2 1 
ATOM   2929 N N   . THR B 2 165 ? 21.00209 17.77851  41.75689  1.000 64.58140  ? 165 THR L N   1 
ATOM   2930 C CA  . THR B 2 165 ? 20.01016 18.23739  40.80344  1.000 75.58946  ? 165 THR L CA  1 
ATOM   2931 C C   . THR B 2 165 ? 18.85251 18.90239  41.54696  1.000 68.58121  ? 165 THR L C   1 
ATOM   2932 O O   . THR B 2 165 ? 18.53374 18.52374  42.67765  1.000 85.39684  ? 165 THR L O   1 
ATOM   2933 C CB  . THR B 2 165 ? 19.49456 17.07553  39.95943  1.000 74.20862  ? 165 THR L CB  1 
ATOM   2934 O OG1 . THR B 2 165 ? 18.97332 16.05107  40.81551  1.000 68.34920  ? 165 THR L OG1 1 
ATOM   2935 C CG2 . THR B 2 165 ? 20.62132 16.49914  39.12169  1.000 74.87420  ? 165 THR L CG2 1 
ATOM   2936 N N   . PRO B 2 166 ? 18.22494 19.91205  40.94520  1.000 57.23797  ? 166 PRO L N   1 
ATOM   2937 C CA  . PRO B 2 166 ? 17.11207 20.58990  41.61970  1.000 74.90559  ? 166 PRO L CA  1 
ATOM   2938 C C   . PRO B 2 166 ? 15.98783 19.62164  41.95883  1.000 77.45162  ? 166 PRO L C   1 
ATOM   2939 O O   . PRO B 2 166 ? 15.65141 18.72924  41.17784  1.000 89.57562  ? 166 PRO L O   1 
ATOM   2940 C CB  . PRO B 2 166 ? 16.66626 21.63397  40.59156  1.000 83.37011  ? 166 PRO L CB  1 
ATOM   2941 C CG  . PRO B 2 166 ? 17.91384 21.93779  39.83219  1.000 70.35708  ? 166 PRO L CG  1 
ATOM   2942 C CD  . PRO B 2 166 ? 18.62461 20.61247  39.71241  1.000 71.03182  ? 166 PRO L CD  1 
ATOM   2943 N N   . SER B 2 167 ? 15.40792 19.80799  43.14224  1.000 76.45396  ? 167 SER L N   1 
ATOM   2944 C CA  . SER B 2 167 ? 14.32822 18.96447  43.63215  1.000 86.44000  ? 167 SER L CA  1 
ATOM   2945 C C   . SER B 2 167 ? 13.19946 19.83900  44.15457  1.000 82.36942  ? 167 SER L C   1 
ATOM   2946 O O   . SER B 2 167 ? 13.44250 20.90479  44.72793  1.000 68.47972  ? 167 SER L O   1 
ATOM   2947 C CB  . SER B 2 167 ? 14.81532 18.01830  44.73717  1.000 80.26147  ? 167 SER L CB  1 
ATOM   2948 O OG  . SER B 2 167 ? 15.31100 18.74423  45.84816  1.000 88.48432  ? 167 SER L OG  1 
ATOM   2949 N N   . LYS B 2 168 ? 11.96684 19.37875  43.95983  1.000 82.97745  ? 168 LYS L N   1 
ATOM   2950 C CA  . LYS B 2 168 ? 10.80391 20.14849  44.37835  1.000 85.07164  ? 168 LYS L CA  1 
ATOM   2951 C C   . LYS B 2 168 ? 10.68240 20.13455  45.89846  1.000 92.87604  ? 168 LYS L C   1 
ATOM   2952 O O   . LYS B 2 168 ? 10.69795 19.06936  46.52336  1.000 81.71351  ? 168 LYS L O   1 
ATOM   2953 C CB  . LYS B 2 168 ? 9.54204  19.58069  43.73010  1.000 86.16740  ? 168 LYS L CB  1 
ATOM   2954 C CG  . LYS B 2 168 ? 8.53786  20.63060  43.28493  1.000 99.53502  ? 168 LYS L CG  1 
ATOM   2955 C CD  . LYS B 2 168 ? 7.40313  20.00274  42.48919  1.000 99.67687  ? 168 LYS L CD  1 
ATOM   2956 C CE  . LYS B 2 168 ? 6.65619  18.96260  43.30860  1.000 118.89785 ? 168 LYS L CE  1 
ATOM   2957 N NZ  . LYS B 2 168 ? 5.66023  18.21844  42.48738  1.000 112.47961 ? 168 LYS L NZ  1 
ATOM   2958 N N   . GLN B 2 169 ? 10.56141 21.32011  46.49431  1.000 84.34605  ? 169 GLN L N   1 
ATOM   2959 C CA  . GLN B 2 169 ? 10.50489 21.44644  47.94267  1.000 78.48829  ? 169 GLN L CA  1 
ATOM   2960 C C   . GLN B 2 169 ? 9.06093  21.34765  48.43062  1.000 88.84826  ? 169 GLN L C   1 
ATOM   2961 O O   . GLN B 2 169 ? 8.14503  20.98550  47.68738  1.000 75.84514  ? 169 GLN L O   1 
ATOM   2962 C CB  . GLN B 2 169 ? 11.12698 22.76177  48.40815  1.000 66.56871  ? 169 GLN L CB  1 
ATOM   2963 C CG  . GLN B 2 169 ? 12.33259 23.24095  47.63201  1.000 80.35494  ? 169 GLN L CG  1 
ATOM   2964 C CD  . GLN B 2 169 ? 12.78439 24.61661  48.09051  1.000 79.13693  ? 169 GLN L CD  1 
ATOM   2965 O OE1 . GLN B 2 169 ? 13.48260 25.32911  47.37168  1.000 89.14597  ? 169 GLN L OE1 1 
ATOM   2966 N NE2 . GLN B 2 169 ? 12.38312 24.99551  49.29814  1.000 93.94397  ? 169 GLN L NE2 1 
ATOM   2967 N N   . SER B 2 170 ? 8.85495  21.67292  49.70869  1.000 109.39437 ? 170 SER L N   1 
ATOM   2968 C CA  . SER B 2 170 ? 7.50898  21.70783  50.26802  1.000 97.54504  ? 170 SER L CA  1 
ATOM   2969 C C   . SER B 2 170 ? 6.66597  22.80158  49.62215  1.000 105.25883 ? 170 SER L C   1 
ATOM   2970 O O   . SER B 2 170 ? 5.47712  22.59632  49.35093  1.000 106.52355 ? 170 SER L O   1 
ATOM   2971 C CB  . SER B 2 170 ? 7.58203  21.90864  51.78037  1.000 107.36763 ? 170 SER L CB  1 
ATOM   2972 O OG  . SER B 2 170 ? 8.39952  23.02125  52.10381  1.000 111.68014 ? 170 SER L OG  1 
ATOM   2973 N N   . ASN B 2 171 ? 7.26174  23.96970  49.36577  1.000 107.00372 ? 171 ASN L N   1 
ATOM   2974 C CA  . ASN B 2 171 ? 6.55080  25.10108  48.78107  1.000 98.76568  ? 171 ASN L CA  1 
ATOM   2975 C C   . ASN B 2 171 ? 6.42290  25.00383  47.26316  1.000 95.19959  ? 171 ASN L C   1 
ATOM   2976 O O   . ASN B 2 171 ? 6.16256  26.02476  46.61317  1.000 105.49031 ? 171 ASN L O   1 
ATOM   2977 C CB  . ASN B 2 171 ? 7.24248  26.41704  49.15156  1.000 97.12779  ? 171 ASN L CB  1 
ATOM   2978 C CG  . ASN B 2 171 ? 8.75375  26.32081  49.08977  1.000 109.16497 ? 171 ASN L CG  1 
ATOM   2979 O OD1 . ASN B 2 171 ? 9.30653  25.66472  48.20828  1.000 97.09335  ? 171 ASN L OD1 1 
ATOM   2980 N ND2 . ASN B 2 171 ? 9.43161  26.99290  50.01510  1.000 128.25416 ? 171 ASN L ND2 1 
ATOM   2981 N N   . ASN B 2 172 ? 6.62425  23.81423  46.69375  1.000 92.88553  ? 172 ASN L N   1 
ATOM   2982 C CA  . ASN B 2 172 ? 6.53912  23.51959  45.26405  1.000 95.49652  ? 172 ASN L CA  1 
ATOM   2983 C C   . ASN B 2 172 ? 7.59086  24.25082  44.43701  1.000 83.21881  ? 172 ASN L C   1 
ATOM   2984 O O   . ASN B 2 172 ? 7.57479  24.15112  43.20299  1.000 78.26618  ? 172 ASN L O   1 
ATOM   2985 C CB  . ASN B 2 172 ? 5.14237  23.81320  44.70301  1.000 95.08032  ? 172 ASN L CB  1 
ATOM   2986 C CG  . ASN B 2 172 ? 4.66710  22.74706  43.73025  1.000 92.80839  ? 172 ASN L CG  1 
ATOM   2987 O OD1 . ASN B 2 172 ? 4.58135  21.56835  44.07443  1.000 82.88615  ? 172 ASN L OD1 1 
ATOM   2988 N ND2 . ASN B 2 172 ? 4.34569  23.16076  42.51090  1.000 109.53415 ? 172 ASN L ND2 1 
ATOM   2989 N N   . LYS B 2 173 ? 8.50855  24.97441  45.07478  1.000 84.22942  ? 173 LYS L N   1 
ATOM   2990 C CA  . LYS B 2 173 ? 9.66390  25.54324  44.39279  1.000 69.39875  ? 173 LYS L CA  1 
ATOM   2991 C C   . LYS B 2 173 ? 10.75017 24.47120  44.29789  1.000 78.04602  ? 173 LYS L C   1 
ATOM   2992 O O   . LYS B 2 173 ? 10.51925 23.29519  44.59018  1.000 71.35342  ? 173 LYS L O   1 
ATOM   2993 C CB  . LYS B 2 173 ? 10.14790 26.79558  45.12021  1.000 85.91587  ? 173 LYS L CB  1 
ATOM   2994 C CG  . LYS B 2 173 ? 9.07556  27.85604  45.34034  1.000 88.81314  ? 173 LYS L CG  1 
ATOM   2995 C CD  . LYS B 2 173 ? 9.59901  29.25271  45.04333  1.000 78.63680  ? 173 LYS L CD  1 
ATOM   2996 C CE  . LYS B 2 173 ? 9.18863  30.23625  46.12889  1.000 85.82570  ? 173 LYS L CE  1 
ATOM   2997 N NZ  . LYS B 2 173 ? 7.77268  30.04179  46.54707  1.000 115.79636 ? 173 LYS L NZ  1 
ATOM   2998 N N   . TYR B 2 174 ? 11.95890 24.86123  43.90270  1.000 77.03712  ? 174 TYR L N   1 
ATOM   2999 C CA  . TYR B 2 174 ? 13.04850 23.91471  43.71962  1.000 73.93480  ? 174 TYR L CA  1 
ATOM   3000 C C   . TYR B 2 174 ? 14.25685 24.32938  44.54795  1.000 68.85945  ? 174 TYR L C   1 
ATOM   3001 O O   . TYR B 2 174 ? 14.48485 25.51758  44.79153  1.000 74.25783  ? 174 TYR L O   1 
ATOM   3002 C CB  . TYR B 2 174 ? 13.43410 23.79841  42.24093  1.000 76.91596  ? 174 TYR L CB  1 
ATOM   3003 C CG  . TYR B 2 174 ? 12.46877 22.95801  41.43284  1.000 80.78947  ? 174 TYR L CG  1 
ATOM   3004 C CD1 . TYR B 2 174 ? 11.24511 23.47321  41.02577  1.000 73.36020  ? 174 TYR L CD1 1 
ATOM   3005 C CD2 . TYR B 2 174 ? 12.78091 21.65216  41.07527  1.000 82.11621  ? 174 TYR L CD2 1 
ATOM   3006 C CE1 . TYR B 2 174 ? 10.35780 22.71227  40.28915  1.000 83.46269  ? 174 TYR L CE1 1 
ATOM   3007 C CE2 . TYR B 2 174 ? 11.89883 20.88265  40.33648  1.000 94.38667  ? 174 TYR L CE2 1 
ATOM   3008 C CZ  . TYR B 2 174 ? 10.68932 21.41840  39.94647  1.000 101.81048 ? 174 TYR L CZ  1 
ATOM   3009 O OH  . TYR B 2 174 ? 9.80809  20.65840  39.21123  1.000 113.16799 ? 174 TYR L OH  1 
ATOM   3010 N N   . ALA B 2 175 ? 15.02427 23.33222  44.98844  1.000 78.97477  ? 175 ALA L N   1 
ATOM   3011 C CA  . ALA B 2 175 ? 16.20420 23.56077  45.80883  1.000 76.67377  ? 175 ALA L CA  1 
ATOM   3012 C C   . ALA B 2 175 ? 17.35822 22.71263  45.29804  1.000 80.95755  ? 175 ALA L C   1 
ATOM   3013 O O   . ALA B 2 175 ? 17.15589 21.65645  44.69370  1.000 83.51526  ? 175 ALA L O   1 
ATOM   3014 C CB  . ALA B 2 175 ? 15.94512 23.23967  47.28659  1.000 71.11601  ? 175 ALA L CB  1 
ATOM   3015 N N   . ALA B 2 176 ? 18.57442 23.18871  45.55327  1.000 82.59305  ? 176 ALA L N   1 
ATOM   3016 C CA  . ALA B 2 176 ? 19.78016 22.46955  45.17442  1.000 75.11233  ? 176 ALA L CA  1 
ATOM   3017 C C   . ALA B 2 176 ? 20.90921 22.88657  46.10348  1.000 66.72709  ? 176 ALA L C   1 
ATOM   3018 O O   . ALA B 2 176 ? 20.84870 23.93126  46.75654  1.000 70.84349  ? 176 ALA L O   1 
ATOM   3019 C CB  . ALA B 2 176 ? 20.15965 22.72816  43.71135  1.000 61.41791  ? 176 ALA L CB  1 
ATOM   3020 N N   . SER B 2 177 ? 21.94343 22.05200  46.15990  1.000 61.44523  ? 177 SER L N   1 
ATOM   3021 C CA  . SER B 2 177 ? 23.10047 22.31867  46.99923  1.000 62.22871  ? 177 SER L CA  1 
ATOM   3022 C C   . SER B 2 177 ? 24.37185 22.03076  46.21603  1.000 69.82992  ? 177 SER L C   1 
ATOM   3023 O O   . SER B 2 177 ? 24.40093 21.15248  45.35046  1.000 68.72317  ? 177 SER L O   1 
ATOM   3024 C CB  . SER B 2 177 ? 23.06962 21.48102  48.28427  1.000 64.49580  ? 177 SER L CB  1 
ATOM   3025 O OG  . SER B 2 177 ? 23.16589 20.09811  47.99345  1.000 72.56314  ? 177 SER L OG  1 
ATOM   3026 N N   . SER B 2 178 ? 25.42380 22.78423  46.52934  1.000 72.60597  ? 178 SER L N   1 
ATOM   3027 C CA  . SER B 2 178 ? 26.72856 22.61198  45.90968  1.000 67.59135  ? 178 SER L CA  1 
ATOM   3028 C C   . SER B 2 178 ? 27.80144 22.58222  46.98775  1.000 69.57939  ? 178 SER L C   1 
ATOM   3029 O O   . SER B 2 178 ? 27.70073 23.27379  48.00463  1.000 78.77434  ? 178 SER L O   1 
ATOM   3030 C CB  . SER B 2 178 ? 27.03072 23.72959  44.90311  1.000 65.30938  ? 178 SER L CB  1 
ATOM   3031 O OG  . SER B 2 178 ? 28.09810 23.36515  44.04524  1.000 66.38095  ? 178 SER L OG  1 
ATOM   3032 N N   . TYR B 2 179 ? 28.83477 21.77536  46.75445  1.000 69.30519  ? 179 TYR L N   1 
ATOM   3033 C CA  . TYR B 2 179 ? 29.90781 21.58477  47.71920  1.000 69.46095  ? 179 TYR L CA  1 
ATOM   3034 C C   . TYR B 2 179 ? 31.26013 21.74705  47.04229  1.000 67.33795  ? 179 TYR L C   1 
ATOM   3035 O O   . TYR B 2 179 ? 31.43538 21.36686  45.88092  1.000 78.31753  ? 179 TYR L O   1 
ATOM   3036 C CB  . TYR B 2 179 ? 29.82668 20.20247  48.38244  1.000 71.65217  ? 179 TYR L CB  1 
ATOM   3037 C CG  . TYR B 2 179 ? 28.54679 19.95698  49.14917  1.000 67.65151  ? 179 TYR L CG  1 
ATOM   3038 C CD1 . TYR B 2 179 ? 27.40745 19.49180  48.50645  1.000 69.67484  ? 179 TYR L CD1 1 
ATOM   3039 C CD2 . TYR B 2 179 ? 28.47865 20.18875  50.51679  1.000 72.95767  ? 179 TYR L CD2 1 
ATOM   3040 C CE1 . TYR B 2 179 ? 26.23560 19.26517  49.20344  1.000 80.79758  ? 179 TYR L CE1 1 
ATOM   3041 C CE2 . TYR B 2 179 ? 27.31105 19.96489  51.22246  1.000 79.30520  ? 179 TYR L CE2 1 
ATOM   3042 C CZ  . TYR B 2 179 ? 26.19297 19.50307  50.56068  1.000 79.19551  ? 179 TYR L CZ  1 
ATOM   3043 O OH  . TYR B 2 179 ? 25.02805 19.27853  51.25784  1.000 73.68211  ? 179 TYR L OH  1 
ATOM   3044 N N   . LEU B 2 180 ? 32.21373 22.31153  47.78064  1.000 76.10418  ? 180 LEU L N   1 
ATOM   3045 C CA  . LEU B 2 180 ? 33.59578 22.45772  47.33403  1.000 80.58721  ? 180 LEU L CA  1 
ATOM   3046 C C   . LEU B 2 180 ? 34.49649 21.73063  48.32301  1.000 80.67720  ? 180 LEU L C   1 
ATOM   3047 O O   . LEU B 2 180 ? 34.64408 22.16567  49.47012  1.000 78.04606  ? 180 LEU L O   1 
ATOM   3048 C CB  . LEU B 2 180 ? 33.98960 23.92982  47.22000  1.000 81.49532  ? 180 LEU L CB  1 
ATOM   3049 C CG  . LEU B 2 180 ? 35.27055 24.21455  46.43037  1.000 85.06808  ? 180 LEU L CG  1 
ATOM   3050 C CD1 . LEU B 2 180 ? 35.33750 23.36186  45.17434  1.000 87.49920  ? 180 LEU L CD1 1 
ATOM   3051 C CD2 . LEU B 2 180 ? 35.39015 25.69217  46.08910  1.000 86.89734  ? 180 LEU L CD2 1 
ATOM   3052 N N   . SER B 2 181 ? 35.09807 20.63018  47.88051  1.000 91.37010  ? 181 SER L N   1 
ATOM   3053 C CA  . SER B 2 181 ? 36.01091 19.85666  48.71200  1.000 96.51220  ? 181 SER L CA  1 
ATOM   3054 C C   . SER B 2 181 ? 37.43103 20.36697  48.50033  1.000 101.25903 ? 181 SER L C   1 
ATOM   3055 O O   . SER B 2 181 ? 37.97817 20.25680  47.39752  1.000 121.91326 ? 181 SER L O   1 
ATOM   3056 C CB  . SER B 2 181 ? 35.91435 18.36793  48.38232  1.000 99.11572  ? 181 SER L CB  1 
ATOM   3057 O OG  . SER B 2 181 ? 34.72540 17.80711  48.91121  1.000 112.97349 ? 181 SER L OG  1 
ATOM   3058 N N   . LEU B 2 182 ? 38.02300 20.92408  49.55397  1.000 88.46055  ? 182 LEU L N   1 
ATOM   3059 C CA  . LEU B 2 182 ? 39.35602 21.50098  49.48897  1.000 85.60654  ? 182 LEU L CA  1 
ATOM   3060 C C   . LEU B 2 182 ? 40.17855 21.03277  50.68076  1.000 98.69013  ? 182 LEU L C   1 
ATOM   3061 O O   . LEU B 2 182 ? 39.64203 20.64339  51.72083  1.000 97.13311  ? 182 LEU L O   1 
ATOM   3062 C CB  . LEU B 2 182 ? 39.30691 23.03531  49.46693  1.000 84.47213  ? 182 LEU L CB  1 
ATOM   3063 C CG  . LEU B 2 182 ? 38.41600 23.69147  48.41161  1.000 103.90464 ? 182 LEU L CG  1 
ATOM   3064 C CD1 . LEU B 2 182 ? 37.98472 25.07391  48.87174  1.000 98.37821  ? 182 LEU L CD1 1 
ATOM   3065 C CD2 . LEU B 2 182 ? 39.12883 23.76519  47.07013  1.000 124.14149 ? 182 LEU L CD2 1 
ATOM   3066 N N   . THR B 2 183 ? 41.49663 21.06686  50.51126  1.000 94.35391  ? 183 THR L N   1 
ATOM   3067 C CA  . THR B 2 183 ? 42.39207 20.78610  51.61871  1.000 88.23263  ? 183 THR L CA  1 
ATOM   3068 C C   . THR B 2 183 ? 42.41936 21.97500  52.57919  1.000 96.54977  ? 183 THR L C   1 
ATOM   3069 O O   . THR B 2 183 ? 42.13581 23.10852  52.18145  1.000 98.57276  ? 183 THR L O   1 
ATOM   3070 C CB  . THR B 2 183 ? 43.80217 20.49662  51.11033  1.000 103.19735 ? 183 THR L CB  1 
ATOM   3071 O OG1 . THR B 2 183 ? 44.42380 21.72003  50.69667  1.000 107.86976 ? 183 THR L OG1 1 
ATOM   3072 C CG2 . THR B 2 183 ? 43.75550 19.53439  49.93227  1.000 107.77584 ? 183 THR L CG2 1 
ATOM   3073 N N   . PRO B 2 184 ? 42.73789 21.73963  53.85703  1.000 105.54092 ? 184 PRO L N   1 
ATOM   3074 C CA  . PRO B 2 184 ? 42.84304 22.87171  54.79418  1.000 98.70663  ? 184 PRO L CA  1 
ATOM   3075 C C   . PRO B 2 184 ? 43.85042 23.91997  54.35707  1.000 92.93813  ? 184 PRO L C   1 
ATOM   3076 O O   . PRO B 2 184 ? 43.62313 25.11800  54.56757  1.000 94.62446  ? 184 PRO L O   1 
ATOM   3077 C CB  . PRO B 2 184 ? 43.25695 22.19398  56.10707  1.000 88.29465  ? 184 PRO L CB  1 
ATOM   3078 C CG  . PRO B 2 184 ? 42.70767 20.81665  55.99934  1.000 87.80242  ? 184 PRO L CG  1 
ATOM   3079 C CD  . PRO B 2 184 ? 42.83377 20.44128  54.54739  1.000 109.00361 ? 184 PRO L CD  1 
ATOM   3080 N N   . GLU B 2 185 ? 44.96515 23.49930  53.75422  1.000 98.09364  ? 185 GLU L N   1 
ATOM   3081 C CA  . GLU B 2 185 ? 45.94494 24.45937  53.25652  1.000 108.00323 ? 185 GLU L CA  1 
ATOM   3082 C C   . GLU B 2 185 ? 45.36018 25.31310  52.13840  1.000 112.55190 ? 185 GLU L C   1 
ATOM   3083 O O   . GLU B 2 185 ? 45.60008 26.52478  52.08155  1.000 108.67469 ? 185 GLU L O   1 
ATOM   3084 C CB  . GLU B 2 185 ? 47.19775 23.72829  52.77291  1.000 116.31217 ? 185 GLU L CB  1 
ATOM   3085 C CG  . GLU B 2 185 ? 47.66993 22.61884  53.69879  1.000 112.88021 ? 185 GLU L CG  1 
ATOM   3086 C CD  . GLU B 2 185 ? 47.21040 21.24681  53.24476  1.000 113.18138 ? 185 GLU L CD  1 
ATOM   3087 O OE1 . GLU B 2 185 ? 47.43287 20.90386  52.06416  1.000 108.48171 ? 185 GLU L OE1 1 
ATOM   3088 O OE2 . GLU B 2 185 ? 46.62682 20.51142  54.06870  1.000 111.05260 ? 185 GLU L OE2 1 
ATOM   3089 N N   . GLN B 2 186 ? 44.58902 24.69634  51.23868  1.000 104.77747 ? 186 GLN L N   1 
ATOM   3090 C CA  . GLN B 2 186 ? 44.00245 25.43424  50.12474  1.000 93.41419  ? 186 GLN L CA  1 
ATOM   3091 C C   . GLN B 2 186 ? 42.95142 26.43327  50.59201  1.000 101.06776 ? 186 GLN L C   1 
ATOM   3092 O O   . GLN B 2 186 ? 42.79162 27.49289  49.97511  1.000 96.17720  ? 186 GLN L O   1 
ATOM   3093 C CB  . GLN B 2 186 ? 43.38850 24.46247  49.11704  1.000 98.18151  ? 186 GLN L CB  1 
ATOM   3094 C CG  . GLN B 2 186 ? 44.36731 23.92135  48.08970  1.000 103.61418 ? 186 GLN L CG  1 
ATOM   3095 C CD  . GLN B 2 186 ? 43.78439 22.78021  47.27874  1.000 105.32080 ? 186 GLN L CD  1 
ATOM   3096 O OE1 . GLN B 2 186 ? 42.84929 22.10809  47.71430  1.000 98.35102  ? 186 GLN L OE1 1 
ATOM   3097 N NE2 . GLN B 2 186 ? 44.33315 22.55789  46.09019  1.000 112.40180 ? 186 GLN L NE2 1 
ATOM   3098 N N   . TRP B 2 187 ? 42.22233 26.11342  51.66418  1.000 93.92706  ? 187 TRP L N   1 
ATOM   3099 C CA  . TRP B 2 187 ? 41.13480 26.98020  52.10962  1.000 96.01517  ? 187 TRP L CA  1 
ATOM   3100 C C   . TRP B 2 187 ? 41.65628 28.33841  52.56527  1.000 95.82900  ? 187 TRP L C   1 
ATOM   3101 O O   . TRP B 2 187 ? 41.10481 29.38234  52.19774  1.000 97.80098  ? 187 TRP L O   1 
ATOM   3102 C CB  . TRP B 2 187 ? 40.34734 26.29903  53.23021  1.000 88.60968  ? 187 TRP L CB  1 
ATOM   3103 C CG  . TRP B 2 187 ? 39.57138 27.25373  54.09228  1.000 89.14005  ? 187 TRP L CG  1 
ATOM   3104 C CD1 . TRP B 2 187 ? 39.72256 27.45367  55.43349  1.000 91.15507  ? 187 TRP L CD1 1 
ATOM   3105 C CD2 . TRP B 2 187 ? 38.52205 28.13646  53.67176  1.000 92.61567  ? 187 TRP L CD2 1 
ATOM   3106 N NE1 . TRP B 2 187 ? 38.83521 28.40555  55.87416  1.000 80.82137  ? 187 TRP L NE1 1 
ATOM   3107 C CE2 . TRP B 2 187 ? 38.08677 28.84044  54.81237  1.000 78.71197  ? 187 TRP L CE2 1 
ATOM   3108 C CE3 . TRP B 2 187 ? 37.90949 28.40016  52.44220  1.000 89.91351  ? 187 TRP L CE3 1 
ATOM   3109 C CZ2 . TRP B 2 187 ? 37.06813 29.78981  54.76029  1.000 80.11620  ? 187 TRP L CZ2 1 
ATOM   3110 C CZ3 . TRP B 2 187 ? 36.89831 29.34321  52.39304  1.000 86.50089  ? 187 TRP L CZ3 1 
ATOM   3111 C CH2 . TRP B 2 187 ? 36.48796 30.02615  53.54452  1.000 82.68389  ? 187 TRP L CH2 1 
ATOM   3112 N N   . LYS B 2 188 ? 42.71852 28.34710  53.36664  1.000 89.50786  ? 188 LYS L N   1 
ATOM   3113 C CA  . LYS B 2 188 ? 43.28553 29.59112  53.86932  1.000 87.58844  ? 188 LYS L CA  1 
ATOM   3114 C C   . LYS B 2 188 ? 44.39297 30.14664  52.98369  1.000 92.33256  ? 188 LYS L C   1 
ATOM   3115 O O   . LYS B 2 188 ? 44.90396 31.23496  53.26824  1.000 80.80400  ? 188 LYS L O   1 
ATOM   3116 C CB  . LYS B 2 188 ? 43.80679 29.39729  55.29761  1.000 91.65403  ? 188 LYS L CB  1 
ATOM   3117 C CG  . LYS B 2 188 ? 42.71704 29.04079  56.29627  1.000 100.20747 ? 188 LYS L CG  1 
ATOM   3118 C CD  . LYS B 2 188 ? 43.26579 28.84459  57.69963  1.000 103.07043 ? 188 LYS L CD  1 
ATOM   3119 C CE  . LYS B 2 188 ? 42.62397 27.64490  58.37755  1.000 112.64042 ? 188 LYS L CE  1 
ATOM   3120 N NZ  . LYS B 2 188 ? 43.41295 27.18002  59.54949  1.000 125.50415 ? 188 LYS L NZ  1 
ATOM   3121 N N   . SER B 2 189 ? 44.77770 29.43280  51.92334  1.000 95.70411  ? 189 SER L N   1 
ATOM   3122 C CA  . SER B 2 189 ? 45.74898 29.98436  50.98423  1.000 97.64862  ? 189 SER L CA  1 
ATOM   3123 C C   . SER B 2 189 ? 45.15644 31.15143  50.20483  1.000 99.51346  ? 189 SER L C   1 
ATOM   3124 O O   . SER B 2 189 ? 45.80825 32.18865  50.03594  1.000 98.35784  ? 189 SER L O   1 
ATOM   3125 C CB  . SER B 2 189 ? 46.23887 28.89545  50.03003  1.000 106.77630 ? 189 SER L CB  1 
ATOM   3126 O OG  . SER B 2 189 ? 47.32556 28.17828  50.58937  1.000 114.45419 ? 189 SER L OG  1 
ATOM   3127 N N   . HIS B 2 190 ? 43.92464 31.00222  49.72704  1.000 102.53626 ? 190 HIS L N   1 
ATOM   3128 C CA  . HIS B 2 190 ? 43.25764 32.06535  48.99317  1.000 98.82961  ? 190 HIS L CA  1 
ATOM   3129 C C   . HIS B 2 190 ? 42.61262 33.05712  49.95369  1.000 100.98170 ? 190 HIS L C   1 
ATOM   3130 O O   . HIS B 2 190 ? 42.25094 32.71834  51.08450  1.000 84.55776  ? 190 HIS L O   1 
ATOM   3131 C CB  . HIS B 2 190 ? 42.20320 31.48573  48.05054  1.000 89.15919  ? 190 HIS L CB  1 
ATOM   3132 C CG  . HIS B 2 190 ? 42.77203 30.62180  46.96877  1.000 92.76954  ? 190 HIS L CG  1 
ATOM   3133 N ND1 . HIS B 2 190 ? 43.12223 29.30487  47.17519  1.000 109.81070 ? 190 HIS L ND1 1 
ATOM   3134 C CD2 . HIS B 2 190 ? 43.05171 30.88626  45.67060  1.000 108.19812 ? 190 HIS L CD2 1 
ATOM   3135 C CE1 . HIS B 2 190 ? 43.59340 28.79524  46.05111  1.000 120.92916 ? 190 HIS L CE1 1 
ATOM   3136 N NE2 . HIS B 2 190 ? 43.56117 29.73409  45.12257  1.000 127.04876 ? 190 HIS L NE2 1 
ATOM   3137 N N   . ARG B 2 191 ? 42.47328 34.29938  49.48851  1.000 98.14062  ? 191 ARG L N   1 
ATOM   3138 C CA  . ARG B 2 191 ? 41.91212 35.34925  50.32987  1.000 86.01996  ? 191 ARG L CA  1 
ATOM   3139 C C   . ARG B 2 191 ? 40.39839 35.23511  50.46296  1.000 85.15705  ? 191 ARG L C   1 
ATOM   3140 O O   . ARG B 2 191 ? 39.84920 35.56693  51.51935  1.000 84.52406  ? 191 ARG L O   1 
ATOM   3141 C CB  . ARG B 2 191 ? 42.29235 36.72355  49.77470  1.000 93.88663  ? 191 ARG L CB  1 
ATOM   3142 C CG  . ARG B 2 191 ? 41.92728 37.88728  50.68204  1.000 104.29209 ? 191 ARG L CG  1 
ATOM   3143 C CD  . ARG B 2 191 ? 40.78448 38.70557  50.10421  1.000 115.07206 ? 191 ARG L CD  1 
ATOM   3144 N NE  . ARG B 2 191 ? 40.26521 39.66933  51.06713  1.000 144.06174 ? 191 ARG L NE  1 
ATOM   3145 C CZ  . ARG B 2 191 ? 39.06764 40.23353  50.99137  1.000 141.78987 ? 191 ARG L CZ  1 
ATOM   3146 N NH1 . ARG B 2 191 ? 38.23605 39.95966  49.99941  1.000 128.81209 ? 191 ARG L NH1 1 
ATOM   3147 N NH2 . ARG B 2 191 ? 38.69500 41.09413  51.93463  1.000 135.90123 ? 191 ARG L NH2 1 
ATOM   3148 N N   . SER B 2 192 ? 39.71050 34.77109  49.42143  1.000 87.84876  ? 192 SER L N   1 
ATOM   3149 C CA  . SER B 2 192 ? 38.25851 34.67995  49.45780  1.000 86.41158  ? 192 SER L CA  1 
ATOM   3150 C C   . SER B 2 192 ? 37.79391 33.54272  48.55965  1.000 82.34202  ? 192 SER L C   1 
ATOM   3151 O O   . SER B 2 192 ? 38.51457 33.09312  47.66488  1.000 84.13415  ? 192 SER L O   1 
ATOM   3152 C CB  . SER B 2 192 ? 37.60242 35.99929  49.03137  1.000 90.02388  ? 192 SER L CB  1 
ATOM   3153 O OG  . SER B 2 192 ? 37.18018 35.94596  47.67978  1.000 107.18944 ? 192 SER L OG  1 
ATOM   3154 N N   . TYR B 2 193 ? 36.57277 33.07934  48.81968  1.000 78.58867  ? 193 TYR L N   1 
ATOM   3155 C CA  . TYR B 2 193 ? 35.92481 32.04041  48.03061  1.000 70.98141  ? 193 TYR L CA  1 
ATOM   3156 C C   . TYR B 2 193 ? 34.49072 32.46819  47.76138  1.000 70.77898  ? 193 TYR L C   1 
ATOM   3157 O O   . TYR B 2 193 ? 33.79871 32.92762  48.67508  1.000 73.30953  ? 193 TYR L O   1 
ATOM   3158 C CB  . TYR B 2 193 ? 35.95294 30.69275  48.75863  1.000 64.17513  ? 193 TYR L CB  1 
ATOM   3159 C CG  . TYR B 2 193 ? 37.18272 29.86134  48.47375  1.000 80.52967  ? 193 TYR L CG  1 
ATOM   3160 C CD1 . TYR B 2 193 ? 38.32555 29.98836  49.25323  1.000 82.52141  ? 193 TYR L CD1 1 
ATOM   3161 C CD2 . TYR B 2 193 ? 37.19985 28.94563  47.42997  1.000 92.98135  ? 193 TYR L CD2 1 
ATOM   3162 C CE1 . TYR B 2 193 ? 39.45204 29.22923  48.99923  1.000 90.67293  ? 193 TYR L CE1 1 
ATOM   3163 C CE2 . TYR B 2 193 ? 38.32152 28.18180  47.16841  1.000 98.48549  ? 193 TYR L CE2 1 
ATOM   3164 C CZ  . TYR B 2 193 ? 39.44452 28.32778  47.95576  1.000 104.65433 ? 193 TYR L CZ  1 
ATOM   3165 O OH  . TYR B 2 193 ? 40.56381 27.56951  47.69920  1.000 117.95974 ? 193 TYR L OH  1 
ATOM   3166 N N   . SER B 2 194 ? 34.04332 32.31364  46.51717  1.000 68.97093  ? 194 SER L N   1 
ATOM   3167 C CA  . SER B 2 194 ? 32.72924 32.78649  46.10559  1.000 72.64042  ? 194 SER L CA  1 
ATOM   3168 C C   . SER B 2 194 ? 31.93506 31.66073  45.46063  1.000 69.26448  ? 194 SER L C   1 
ATOM   3169 O O   . SER B 2 194 ? 32.49105 30.82710  44.73939  1.000 72.73877  ? 194 SER L O   1 
ATOM   3170 C CB  . SER B 2 194 ? 32.84366 33.96364  45.12800  1.000 74.68448  ? 194 SER L CB  1 
ATOM   3171 O OG  . SER B 2 194 ? 33.87432 34.85439  45.51871  1.000 85.40528  ? 194 SER L OG  1 
ATOM   3172 N N   . CYS B 2 195 ? 30.63151 31.64565  45.72772  1.000 75.47782  ? 195 CYS L N   1 
ATOM   3173 C CA  . CYS B 2 195 ? 29.69615 30.71442  45.10940  1.000 70.59055  ? 195 CYS L CA  1 
ATOM   3174 C C   . CYS B 2 195 ? 28.72793 31.51360  44.24790  1.000 80.55042  ? 195 CYS L C   1 
ATOM   3175 O O   . CYS B 2 195 ? 28.03339 32.40274  44.75251  1.000 79.96448  ? 195 CYS L O   1 
ATOM   3176 C CB  . CYS B 2 195 ? 28.94176 29.90689  46.16667  1.000 69.37116  ? 195 CYS L CB  1 
ATOM   3177 S SG  . CYS B 2 195 ? 27.71024 28.76159  45.49635  1.000 102.74912 ? 195 CYS L SG  1 
ATOM   3178 N N   . GLN B 2 196 ? 28.68223 31.19717  42.95702  1.000 90.59400  ? 196 GLN L N   1 
ATOM   3179 C CA  . GLN B 2 196 ? 27.87398 31.92945  41.99132  1.000 81.11413  ? 196 GLN L CA  1 
ATOM   3180 C C   . GLN B 2 196 ? 26.77829 31.02339  41.44892  1.000 78.35618  ? 196 GLN L C   1 
ATOM   3181 O O   . GLN B 2 196 ? 27.06106 29.92446  40.96000  1.000 83.94665  ? 196 GLN L O   1 
ATOM   3182 C CB  . GLN B 2 196 ? 28.73912 32.45599  40.84411  1.000 76.63115  ? 196 GLN L CB  1 
ATOM   3183 C CG  . GLN B 2 196 ? 28.66922 33.95968  40.64606  1.000 86.20602  ? 196 GLN L CG  1 
ATOM   3184 C CD  . GLN B 2 196 ? 29.76621 34.47566  39.73507  1.000 105.41212 ? 196 GLN L CD  1 
ATOM   3185 O OE1 . GLN B 2 196 ? 30.82333 34.90374  40.19805  1.000 96.48350  ? 196 GLN L OE1 1 
ATOM   3186 N NE2 . GLN B 2 196 ? 29.51958 34.43644  38.43034  1.000 113.10875 ? 196 GLN L NE2 1 
ATOM   3187 N N   . VAL B 2 197 ? 25.53407 31.48807  41.53183  1.000 82.35281  ? 197 VAL L N   1 
ATOM   3188 C CA  . VAL B 2 197 ? 24.37403 30.75272  41.04278  1.000 91.34347  ? 197 VAL L CA  1 
ATOM   3189 C C   . VAL B 2 197 ? 23.67544 31.60475  39.99330  1.000 82.24115  ? 197 VAL L C   1 
ATOM   3190 O O   . VAL B 2 197 ? 23.34834 32.76922  40.24952  1.000 91.19311  ? 197 VAL L O   1 
ATOM   3191 C CB  . VAL B 2 197 ? 23.40541 30.38986  42.18354  1.000 75.37244  ? 197 VAL L CB  1 
ATOM   3192 C CG1 . VAL B 2 197 ? 22.30056 29.47880  41.67038  1.000 78.07189  ? 197 VAL L CG1 1 
ATOM   3193 C CG2 . VAL B 2 197 ? 24.15648 29.73347  43.33055  1.000 75.35069  ? 197 VAL L CG2 1 
ATOM   3194 N N   . THR B 2 198 ? 23.44808 31.02582  38.81846  1.000 72.36517  ? 198 THR L N   1 
ATOM   3195 C CA  . THR B 2 198 ? 22.77662 31.70400  37.71850  1.000 80.32328  ? 198 THR L CA  1 
ATOM   3196 C C   . THR B 2 198 ? 21.43772 31.03043  37.45448  1.000 76.63266  ? 198 THR L C   1 
ATOM   3197 O O   . THR B 2 198 ? 21.37675 29.80892  37.27811  1.000 74.04698  ? 198 THR L O   1 
ATOM   3198 C CB  . THR B 2 198 ? 23.63553 31.68573  36.45184  1.000 81.61337  ? 198 THR L CB  1 
ATOM   3199 O OG1 . THR B 2 198 ? 24.92237 32.24863  36.73592  1.000 96.15946  ? 198 THR L OG1 1 
ATOM   3200 C CG2 . THR B 2 198 ? 22.96999 32.48917  35.34458  1.000 89.91695  ? 198 THR L CG2 1 
ATOM   3201 N N   . HIS B 2 199 ? 20.37075 31.82663  37.42936  1.000 74.20147  ? 199 HIS L N   1 
ATOM   3202 C CA  . HIS B 2 199 ? 19.02438 31.31719  37.19546  1.000 66.67699  ? 199 HIS L CA  1 
ATOM   3203 C C   . HIS B 2 199 ? 18.27671 32.29644  36.30651  1.000 83.37092  ? 199 HIS L C   1 
ATOM   3204 O O   . HIS B 2 199 ? 18.11092 33.46393  36.67425  1.000 77.74087  ? 199 HIS L O   1 
ATOM   3205 C CB  . HIS B 2 199 ? 18.27363 31.11091  38.51366  1.000 69.43378  ? 199 HIS L CB  1 
ATOM   3206 C CG  . HIS B 2 199 ? 16.83635 30.73190  38.33747  1.000 66.61762  ? 199 HIS L CG  1 
ATOM   3207 N ND1 . HIS B 2 199 ? 15.80174 31.61675  38.55259  1.000 62.66995  ? 199 HIS L ND1 1 
ATOM   3208 C CD2 . HIS B 2 199 ? 16.26102 29.56285  37.96916  1.000 63.09552  ? 199 HIS L CD2 1 
ATOM   3209 C CE1 . HIS B 2 199 ? 14.65120 31.00965  38.32299  1.000 64.08181  ? 199 HIS L CE1 1 
ATOM   3210 N NE2 . HIS B 2 199 ? 14.90188 29.76238  37.96793  1.000 67.22269  ? 199 HIS L NE2 1 
ATOM   3211 N N   . GLU B 2 200 ? 17.82475 31.81532  35.14552  1.000 75.40083  ? 200 GLU L N   1 
ATOM   3212 C CA  . GLU B 2 200 ? 17.04456 32.61748  34.20116  1.000 70.92155  ? 200 GLU L CA  1 
ATOM   3213 C C   . GLU B 2 200 ? 17.78039 33.89914  33.81487  1.000 86.38836  ? 200 GLU L C   1 
ATOM   3214 O O   . GLU B 2 200 ? 17.18435 34.97319  33.71119  1.000 83.89651  ? 200 GLU L O   1 
ATOM   3215 C CB  . GLU B 2 200 ? 15.65867 32.93538  34.76623  1.000 59.44127  ? 200 GLU L CB  1 
ATOM   3216 C CG  . GLU B 2 200 ? 14.69669 31.76064  34.74200  1.000 65.21377  ? 200 GLU L CG  1 
ATOM   3217 C CD  . GLU B 2 200 ? 13.37861 32.10278  34.07971  1.000 89.02620  ? 200 GLU L CD  1 
ATOM   3218 O OE1 . GLU B 2 200 ? 12.64197 32.94765  34.62910  1.000 93.18306  ? 200 GLU L OE1 1 
ATOM   3219 O OE2 . GLU B 2 200 ? 13.07815 31.52687  33.01243  1.000 112.28471 ? 200 GLU L OE2 1 
ATOM   3220 N N   . GLY B 2 201 ? 19.07872 33.78678  33.60189  1.000 77.39819  ? 201 GLY L N   1 
ATOM   3221 C CA  . GLY B 2 201 ? 19.90585 34.94138  33.26771  1.000 77.87736  ? 201 GLY L CA  1 
ATOM   3222 C C   . GLY B 2 201 ? 20.51965 35.65208  34.45556  1.000 110.98286 ? 201 GLY L C   1 
ATOM   3223 O O   . GLY B 2 201 ? 21.71846 35.92781  34.46264  1.000 122.96515 ? 201 GLY L O   1 
ATOM   3224 N N   . SER B 2 202 ? 19.70883 35.95175  35.46752  1.000 97.72628  ? 202 SER L N   1 
ATOM   3225 C CA  . SER B 2 202 ? 20.20380 36.63860  36.65135  1.000 94.43377  ? 202 SER L CA  1 
ATOM   3226 C C   . SER B 2 202 ? 21.17705 35.75406  37.42322  1.000 103.50690 ? 202 SER L C   1 
ATOM   3227 O O   . SER B 2 202 ? 21.06130 34.52556  37.43747  1.000 87.95701  ? 202 SER L O   1 
ATOM   3228 C CB  . SER B 2 202 ? 19.04217 37.04976  37.55567  1.000 113.64574 ? 202 SER L CB  1 
ATOM   3229 O OG  . SER B 2 202 ? 19.51392 37.55758  38.79215  1.000 121.61125 ? 202 SER L OG  1 
ATOM   3230 N N   . THR B 2 203 ? 22.14812 36.39656  38.06953  1.000 107.36332 ? 203 THR L N   1 
ATOM   3231 C CA  . THR B 2 203 ? 23.18492 35.70375  38.82237  1.000 89.80586  ? 203 THR L CA  1 
ATOM   3232 C C   . THR B 2 203 ? 23.24279 36.26102  40.23638  1.000 88.83974  ? 203 THR L C   1 
ATOM   3233 O O   . THR B 2 203 ? 23.27802 37.48111  40.42502  1.000 91.87087  ? 203 THR L O   1 
ATOM   3234 C CB  . THR B 2 203 ? 24.55240 35.84632  38.14408  1.000 101.46796 ? 203 THR L CB  1 
ATOM   3235 O OG1 . THR B 2 203 ? 24.46358 35.39694  36.78632  1.000 110.11107 ? 203 THR L OG1 1 
ATOM   3236 C CG2 . THR B 2 203 ? 25.59979 35.02183  38.87605  1.000 86.53455  ? 203 THR L CG2 1 
ATOM   3237 N N   . VAL B 2 204 ? 23.25364 35.36693  41.22281  1.000 103.73217 ? 204 VAL L N   1 
ATOM   3238 C CA  . VAL B 2 204 ? 23.37558 35.72668  42.63085  1.000 79.11507  ? 204 VAL L CA  1 
ATOM   3239 C C   . VAL B 2 204 ? 24.67367 35.13247  43.15726  1.000 85.99381  ? 204 VAL L C   1 
ATOM   3240 O O   . VAL B 2 204 ? 24.91571 33.92904  43.00773  1.000 81.45877  ? 204 VAL L O   1 
ATOM   3241 C CB  . VAL B 2 204 ? 22.17324 35.23043  43.45463  1.000 61.08148  ? 204 VAL L CB  1 
ATOM   3242 C CG1 . VAL B 2 204 ? 22.26047 35.74742  44.88177  1.000 93.88209  ? 204 VAL L CG1 1 
ATOM   3243 C CG2 . VAL B 2 204 ? 20.86909 35.66307  42.80447  1.000 87.27538  ? 204 VAL L CG2 1 
ATOM   3244 N N   . GLU B 2 205 ? 25.50343 35.97232  43.77154  1.000 84.03168  ? 205 GLU L N   1 
ATOM   3245 C CA  . GLU B 2 205 ? 26.83054 35.57893  44.22492  1.000 74.69685  ? 205 GLU L CA  1 
ATOM   3246 C C   . GLU B 2 205 ? 26.92298 35.70977  45.73782  1.000 84.41027  ? 205 GLU L C   1 
ATOM   3247 O O   . GLU B 2 205 ? 26.48567 36.71534  46.30699  1.000 98.26710  ? 205 GLU L O   1 
ATOM   3248 C CB  . GLU B 2 205 ? 27.91262 36.43139  43.55538  1.000 78.13163  ? 205 GLU L CB  1 
ATOM   3249 C CG  . GLU B 2 205 ? 29.33047 35.94393  43.80358  1.000 88.09234  ? 205 GLU L CG  1 
ATOM   3250 C CD  . GLU B 2 205 ? 30.36632 37.03027  43.58911  1.000 98.64671  ? 205 GLU L CD  1 
ATOM   3251 O OE1 . GLU B 2 205 ? 30.39418 37.99309  44.38470  1.000 101.24863 ? 205 GLU L OE1 1 
ATOM   3252 O OE2 . GLU B 2 205 ? 31.15307 36.92128  42.62502  1.000 103.66763 ? 205 GLU L OE2 1 
ATOM   3253 N N   . LYS B 2 206 ? 27.48956 34.69162  46.38103  1.000 88.26816  ? 206 LYS L N   1 
ATOM   3254 C CA  . LYS B 2 206 ? 27.77599 34.70580  47.80909  1.000 77.94850  ? 206 LYS L CA  1 
ATOM   3255 C C   . LYS B 2 206 ? 29.25404 34.40615  48.00945  1.000 72.78520  ? 206 LYS L C   1 
ATOM   3256 O O   . LYS B 2 206 ? 29.78447 33.46225  47.41466  1.000 82.66040  ? 206 LYS L O   1 
ATOM   3257 C CB  . LYS B 2 206 ? 26.91522 33.68577  48.55952  1.000 71.75582  ? 206 LYS L CB  1 
ATOM   3258 C CG  . LYS B 2 206 ? 26.00997 34.29579  49.61773  1.000 76.31503  ? 206 LYS L CG  1 
ATOM   3259 C CD  . LYS B 2 206 ? 25.22147 35.46915  49.06046  1.000 85.12765  ? 206 LYS L CD  1 
ATOM   3260 C CE  . LYS B 2 206 ? 24.03808 35.81247  49.94983  1.000 90.27598  ? 206 LYS L CE  1 
ATOM   3261 N NZ  . LYS B 2 206 ? 22.98334 36.55368  49.20416  1.000 111.55602 ? 206 LYS L NZ  1 
ATOM   3262 N N   . THR B 2 207 ? 29.91531 35.20741  48.84120  1.000 73.80415  ? 207 THR L N   1 
ATOM   3263 C CA  . THR B 2 207 ? 31.35383 35.10738  49.04046  1.000 81.54292  ? 207 THR L CA  1 
ATOM   3264 C C   . THR B 2 207 ? 31.66940 35.01639  50.52628  1.000 74.05472  ? 207 THR L C   1 
ATOM   3265 O O   . THR B 2 207 ? 31.08744 35.74065  51.33935  1.000 74.10219  ? 207 THR L O   1 
ATOM   3266 C CB  . THR B 2 207 ? 32.08093 36.31270  48.42257  1.000 90.69745  ? 207 THR L CB  1 
ATOM   3267 O OG1 . THR B 2 207 ? 31.74266 36.41566  47.03376  1.000 74.63511  ? 207 THR L OG1 1 
ATOM   3268 C CG2 . THR B 2 207 ? 33.59024 36.16510  48.56037  1.000 88.15402  ? 207 THR L CG2 1 
ATOM   3269 N N   . VAL B 2 208 ? 32.59404 34.11934  50.87501  1.000 74.20886  ? 208 VAL L N   1 
ATOM   3270 C CA  . VAL B 2 208 ? 33.07343 33.97053  52.24141  1.000 75.72135  ? 208 VAL L CA  1 
ATOM   3271 C C   . VAL B 2 208 ? 34.59590 33.99465  52.22730  1.000 80.42712  ? 208 VAL L C   1 
ATOM   3272 O O   . VAL B 2 208 ? 35.23902 33.67592  51.22493  1.000 86.67749  ? 208 VAL L O   1 
ATOM   3273 C CB  . VAL B 2 208 ? 32.56470 32.67483  52.91107  1.000 73.24885  ? 208 VAL L CB  1 
ATOM   3274 C CG1 . VAL B 2 208 ? 31.05349 32.72348  53.09206  1.000 71.24127  ? 208 VAL L CG1 1 
ATOM   3275 C CG2 . VAL B 2 208 ? 32.98305 31.45522  52.10362  1.000 70.99426  ? 208 VAL L CG2 1 
ATOM   3276 N N   . ALA B 2 209 ? 35.16861 34.38091  53.36221  1.000 80.93923  ? 209 ALA L N   1 
ATOM   3277 C CA  . ALA B 2 209 ? 36.60958 34.45894  53.52866  1.000 80.68265  ? 209 ALA L CA  1 
ATOM   3278 C C   . ALA B 2 209 ? 37.01465 33.79454  54.83461  1.000 83.85971  ? 209 ALA L C   1 
ATOM   3279 O O   . ALA B 2 209 ? 36.21937 33.73676  55.77800  1.000 89.31208  ? 209 ALA L O   1 
ATOM   3280 C CB  . ALA B 2 209 ? 37.09158 35.91735  53.52116  1.000 85.12681  ? 209 ALA L CB  1 
ATOM   3281 N N   . PRO B 2 210 ? 38.24435 33.27361  54.91640  1.000 89.38627  ? 210 PRO L N   1 
ATOM   3282 C CA  . PRO B 2 210 ? 38.69799 32.65952  56.17201  1.000 96.37777  ? 210 PRO L CA  1 
ATOM   3283 C C   . PRO B 2 210 ? 38.78989 33.66494  57.30856  1.000 99.96283  ? 210 PRO L C   1 
ATOM   3284 O O   . PRO B 2 210 ? 39.65278 34.54894  57.29380  1.000 99.71564  ? 210 PRO L O   1 
ATOM   3285 C CB  . PRO B 2 210 ? 40.07864 32.09884  55.80596  1.000 88.63483  ? 210 PRO L CB  1 
ATOM   3286 C CG  . PRO B 2 210 ? 40.01131 31.88615  54.32811  1.000 95.86337  ? 210 PRO L CG  1 
ATOM   3287 C CD  . PRO B 2 210 ? 39.19942 33.04217  53.81941  1.000 92.41374  ? 210 PRO L CD  1 
ATOM   3288 N N   . THR B 2 211 ? 37.90872 33.52263  58.29743  1.000 122.04052 ? 211 THR L N   1 
ATOM   3289 C CA  . THR B 2 211 ? 37.85194 34.40990  59.46029  1.000 117.52886 ? 211 THR L CA  1 
ATOM   3290 C C   . THR B 2 211 ? 37.84336 35.88653  59.06864  1.000 107.64229 ? 211 THR L C   1 
ATOM   3291 O O   . THR B 2 211 ? 36.80202 36.54205  59.10029  1.000 104.29489 ? 211 THR L O   1 
ATOM   3292 C CB  . THR B 2 211 ? 39.02993 34.15439  60.42121  1.000 112.06551 ? 211 THR L CB  1 
ATOM   3293 O OG1 . THR B 2 211 ? 39.21837 32.74336  60.58476  1.000 109.85306 ? 211 THR L OG1 1 
ATOM   3294 C CG2 . THR B 2 211 ? 38.75545 34.78375  61.77822  1.000 94.66830  ? 211 THR L CG2 1 
ATOM   3295 N N   . ALA C 3 1   ? 4.89945  4.47043   -37.77395 1.000 161.82967 ? 52  ALA E N   1 
ATOM   3296 C CA  . ALA C 3 1   ? 4.48882  5.11794   -36.53393 1.000 159.65782 ? 52  ALA E CA  1 
ATOM   3297 C C   . ALA C 3 1   ? 5.70094  5.48752   -35.68459 1.000 170.57940 ? 52  ALA E C   1 
ATOM   3298 O O   . ALA C 3 1   ? 6.63376  4.69734   -35.55197 1.000 165.98521 ? 52  ALA E O   1 
ATOM   3299 C CB  . ALA C 3 1   ? 3.54655  4.21575   -35.75159 1.000 144.82181 ? 52  ALA E CB  1 
ATOM   3300 N N   . PRO C 3 2   ? 5.69494  6.69197   -35.12467 1.000 178.92604 ? 53  PRO E N   1 
ATOM   3301 C CA  . PRO C 3 2   ? 6.78736  7.12365   -34.25283 1.000 176.11027 ? 53  PRO E CA  1 
ATOM   3302 C C   . PRO C 3 2   ? 6.48415  6.84993   -32.78263 1.000 175.95860 ? 53  PRO E C   1 
ATOM   3303 O O   . PRO C 3 2   ? 5.37606  6.46423   -32.40537 1.000 167.52523 ? 53  PRO E O   1 
ATOM   3304 C CB  . PRO C 3 2   ? 6.85841  8.63021   -34.52623 1.000 169.54162 ? 53  PRO E CB  1 
ATOM   3305 C CG  . PRO C 3 2   ? 5.43279  9.01077   -34.84294 1.000 166.75662 ? 53  PRO E CG  1 
ATOM   3306 C CD  . PRO C 3 2   ? 4.71376  7.76908   -35.34392 1.000 174.82721 ? 53  PRO E CD  1 
ATOM   3307 N N   . LEU C 3 3   ? 7.50598  7.05804   -31.95365 1.000 179.15839 ? 54  LEU E N   1 
ATOM   3308 C CA  . LEU C 3 3   ? 7.38892  6.95383   -30.50175 1.000 175.40528 ? 54  LEU E CA  1 
ATOM   3309 C C   . LEU C 3 3   ? 7.74044  8.30649   -29.89689 1.000 179.08024 ? 54  LEU E C   1 
ATOM   3310 O O   . LEU C 3 3   ? 8.91711  8.68043   -29.84053 1.000 174.94377 ? 54  LEU E O   1 
ATOM   3311 C CB  . LEU C 3 3   ? 8.29235  5.85235   -29.94741 1.000 169.59440 ? 54  LEU E CB  1 
ATOM   3312 C CG  . LEU C 3 3   ? 8.27987  5.67445   -28.42666 1.000 165.53096 ? 54  LEU E CG  1 
ATOM   3313 C CD1 . LEU C 3 3   ? 6.91730  5.20941   -27.94754 1.000 160.03913 ? 54  LEU E CD1 1 
ATOM   3314 C CD2 . LEU C 3 3   ? 9.36120  4.69879   -27.99043 1.000 148.07307 ? 54  LEU E CD2 1 
ATOM   3315 N N   . GLN C 3 4   ? 6.72301  9.03560   -29.44728 1.000 181.55691 ? 55  GLN E N   1 
ATOM   3316 C CA  . GLN C 3 4   ? 6.91443  10.33736  -28.82368 1.000 182.21518 ? 55  GLN E CA  1 
ATOM   3317 C C   . GLN C 3 4   ? 7.02341  10.15828  -27.31533 1.000 185.26345 ? 55  GLN E C   1 
ATOM   3318 O O   . GLN C 3 4   ? 6.14292  9.55589   -26.69304 1.000 185.99026 ? 55  GLN E O   1 
ATOM   3319 C CB  . GLN C 3 4   ? 5.75429  11.27380  -29.16455 1.000 183.07258 ? 55  GLN E CB  1 
ATOM   3320 C CG  . GLN C 3 4   ? 5.49228  11.43070  -30.65551 1.000 189.64069 ? 55  GLN E CG  1 
ATOM   3321 C CD  . GLN C 3 4   ? 6.59780  12.18204  -31.37093 1.000 197.68349 ? 55  GLN E CD  1 
ATOM   3322 O OE1 . GLN C 3 4   ? 7.14967  13.14877  -30.84488 1.000 204.61161 ? 55  GLN E OE1 1 
ATOM   3323 N NE2 . GLN C 3 4   ? 6.92482  11.74160  -32.58045 1.000 184.51288 ? 55  GLN E NE2 1 
ATOM   3324 N N   . LEU C 3 5   ? 8.10610  10.67795  -26.72719 1.000 183.11705 ? 56  LEU E N   1 
ATOM   3325 C CA  . LEU C 3 5   ? 8.37431  10.50580  -25.29693 1.000 185.46074 ? 56  LEU E CA  1 
ATOM   3326 C C   . LEU C 3 5   ? 8.56998  11.87750  -24.65069 1.000 186.59544 ? 56  LEU E C   1 
ATOM   3327 O O   . LEU C 3 5   ? 9.70715  12.30119  -24.43059 1.000 195.45918 ? 56  LEU E O   1 
ATOM   3328 C CB  . LEU C 3 5   ? 9.59888  9.60854   -25.09059 1.000 184.56095 ? 56  LEU E CB  1 
ATOM   3329 C CG  . LEU C 3 5   ? 9.52119  8.16897   -25.60166 1.000 174.33778 ? 56  LEU E CG  1 
ATOM   3330 C CD1 . LEU C 3 5   ? 10.86027 7.46821   -25.42022 1.000 154.57112 ? 56  LEU E CD1 1 
ATOM   3331 C CD2 . LEU C 3 5   ? 8.41247  7.40423   -24.89601 1.000 173.31435 ? 56  LEU E CD2 1 
ATOM   3332 N N   . GLY C 3 6   ? 7.45558  12.55071  -24.34629 1.000 183.07758 ? 57  GLY E N   1 
ATOM   3333 C CA  . GLY C 3 6   ? 7.41176  13.71502  -23.47322 1.000 186.22551 ? 57  GLY E CA  1 
ATOM   3334 C C   . GLY C 3 6   ? 8.59696  14.65614  -23.54420 1.000 190.05264 ? 57  GLY E C   1 
ATOM   3335 O O   . GLY C 3 6   ? 9.02297  15.06363  -24.62931 1.000 197.20764 ? 57  GLY E O   1 
ATOM   3336 N N   . ASN C 3 7   ? 9.12987  15.01581  -22.37699 1.000 187.82937 ? 58  ASN E N   1 
ATOM   3337 C CA  . ASN C 3 7   ? 10.47324 15.56615  -22.28399 1.000 191.26698 ? 58  ASN E CA  1 
ATOM   3338 C C   . ASN C 3 7   ? 11.52023 14.47750  -22.10660 1.000 188.10208 ? 58  ASN E C   1 
ATOM   3339 O O   . ASN C 3 7   ? 12.71857 14.77804  -22.11994 1.000 185.08340 ? 58  ASN E O   1 
ATOM   3340 C CB  . ASN C 3 7   ? 10.59470 16.53666  -21.10338 1.000 196.69844 ? 58  ASN E CB  1 
ATOM   3341 C CG  . ASN C 3 7   ? 9.52035  17.60563  -21.09140 1.000 204.40338 ? 58  ASN E CG  1 
ATOM   3342 O OD1 . ASN C 3 7   ? 9.00395  18.01404  -22.13284 1.000 202.81955 ? 58  ASN E OD1 1 
ATOM   3343 N ND2 . ASN C 3 7   ? 9.19247  18.07400  -19.88746 1.000 206.39402 ? 58  ASN E ND2 1 
ATOM   3344 N N   . CYS C 3 8   ? 11.08983 13.22916  -21.94730 1.000 187.92823 ? 59  CYS E N   1 
ATOM   3345 C CA  . CYS C 3 8   ? 11.93381 12.14156  -21.48620 1.000 176.15365 ? 59  CYS E CA  1 
ATOM   3346 C C   . CYS C 3 8   ? 12.86584 11.65679  -22.59292 1.000 166.26083 ? 59  CYS E C   1 
ATOM   3347 O O   . CYS C 3 8   ? 12.71033 11.98364  -23.77261 1.000 182.36069 ? 59  CYS E O   1 
ATOM   3348 C CB  . CYS C 3 8   ? 11.07202 10.98497  -20.98396 1.000 172.12157 ? 59  CYS E CB  1 
ATOM   3349 S SG  . CYS C 3 8   ? 10.18650 11.32685  -19.44950 1.000 172.33852 ? 59  CYS E SG  1 
ATOM   3350 N N   . SER C 3 9   ? 13.85014 10.86129  -22.18821 1.000 141.70961 ? 60  SER E N   1 
ATOM   3351 C CA  . SER C 3 9   ? 14.78915 10.23267  -23.09877 1.000 144.35360 ? 60  SER E CA  1 
ATOM   3352 C C   . SER C 3 9   ? 14.45016 8.75119   -23.24436 1.000 143.07450 ? 60  SER E C   1 
ATOM   3353 O O   . SER C 3 9   ? 13.46076 8.25373   -22.70059 1.000 139.60867 ? 60  SER E O   1 
ATOM   3354 C CB  . SER C 3 9   ? 16.22365 10.42818  -22.60384 1.000 144.61565 ? 60  SER E CB  1 
ATOM   3355 O OG  . SER C 3 9   ? 16.40766 9.83798   -21.32855 1.000 137.29251 ? 60  SER E OG  1 
ATOM   3356 N N   . ILE C 3 10  ? 15.28660 8.03882   -24.00129 1.000 144.68353 ? 61  ILE E N   1 
ATOM   3357 C CA  . ILE C 3 10  ? 15.08975 6.60326   -24.17438 1.000 139.22402 ? 61  ILE E CA  1 
ATOM   3358 C C   . ILE C 3 10  ? 15.27739 5.87467   -22.84968 1.000 126.00020 ? 61  ILE E C   1 
ATOM   3359 O O   . ILE C 3 10  ? 14.50465 4.97121   -22.50746 1.000 121.48047 ? 61  ILE E O   1 
ATOM   3360 C CB  . ILE C 3 10  ? 16.03778 6.06262   -25.25972 1.000 134.09652 ? 61  ILE E CB  1 
ATOM   3361 C CG1 . ILE C 3 10  ? 15.79031 6.78250   -26.58602 1.000 148.39318 ? 61  ILE E CG1 1 
ATOM   3362 C CG2 . ILE C 3 10  ? 15.85763 4.56135   -25.42851 1.000 120.10785 ? 61  ILE E CG2 1 
ATOM   3363 C CD1 . ILE C 3 10  ? 16.74696 6.38167   -27.68377 1.000 149.72305 ? 61  ILE E CD1 1 
ATOM   3364 N N   . ALA C 3 11  ? 16.30561 6.25298   -22.08538 1.000 121.62527 ? 62  ALA E N   1 
ATOM   3365 C CA  . ALA C 3 11  ? 16.56149 5.59943   -20.80564 1.000 121.81288 ? 62  ALA E CA  1 
ATOM   3366 C C   . ALA C 3 11  ? 15.41372 5.81779   -19.82818 1.000 110.37900 ? 62  ALA E C   1 
ATOM   3367 O O   . ALA C 3 11  ? 14.99720 4.88472   -19.13272 1.000 106.33502 ? 62  ALA E O   1 
ATOM   3368 C CB  . ALA C 3 11  ? 17.87402 6.10719   -20.20976 1.000 102.11425 ? 62  ALA E CB  1 
ATOM   3369 N N   . GLY C 3 12  ? 14.88746 7.04256   -19.76362 1.000 103.52577 ? 63  GLY E N   1 
ATOM   3370 C CA  . GLY C 3 12  ? 13.82205 7.32997   -18.81622 1.000 107.89290 ? 63  GLY E CA  1 
ATOM   3371 C C   . GLY C 3 12  ? 12.57467 6.50350   -19.06072 1.000 109.67493 ? 63  GLY E C   1 
ATOM   3372 O O   . GLY C 3 12  ? 11.95999 5.99527   -18.11983 1.000 115.31727 ? 63  GLY E O   1 
ATOM   3373 N N   . TRP C 3 13  ? 12.18472 6.35452   -20.32737 1.000 119.59776 ? 64  TRP E N   1 
ATOM   3374 C CA  . TRP C 3 13  ? 10.99973 5.56562   -20.64131 1.000 123.42684 ? 64  TRP E CA  1 
ATOM   3375 C C   . TRP C 3 13  ? 11.26644 4.07132   -20.49889 1.000 119.14781 ? 64  TRP E C   1 
ATOM   3376 O O   . TRP C 3 13  ? 10.34036 3.30240   -20.21666 1.000 112.57702 ? 64  TRP E O   1 
ATOM   3377 C CB  . TRP C 3 13  ? 10.51074 5.90481   -22.05096 1.000 115.73416 ? 64  TRP E CB  1 
ATOM   3378 C CG  . TRP C 3 13  ? 9.92764  4.74802   -22.79896 1.000 125.31276 ? 64  TRP E CG  1 
ATOM   3379 C CD1 . TRP C 3 13  ? 8.68692  4.20386   -22.63288 1.000 114.94508 ? 64  TRP E CD1 1 
ATOM   3380 C CD2 . TRP C 3 13  ? 10.56124 3.99328   -23.83751 1.000 125.18411 ? 64  TRP E CD2 1 
ATOM   3381 N NE1 . TRP C 3 13  ? 8.51029  3.15507   -23.50251 1.000 116.44086 ? 64  TRP E NE1 1 
ATOM   3382 C CE2 . TRP C 3 13  ? 9.64668  3.00549   -24.25335 1.000 125.84041 ? 64  TRP E CE2 1 
ATOM   3383 C CE3 . TRP C 3 13  ? 11.81381 4.05622   -24.45541 1.000 122.13001 ? 64  TRP E CE3 1 
ATOM   3384 C CZ2 . TRP C 3 13  ? 9.94513  2.08843   -25.25868 1.000 141.70385 ? 64  TRP E CZ2 1 
ATOM   3385 C CZ3 . TRP C 3 13  ? 12.10792 3.14576   -25.45204 1.000 126.61357 ? 64  TRP E CZ3 1 
ATOM   3386 C CH2 . TRP C 3 13  ? 11.17814 2.17489   -25.84433 1.000 139.21709 ? 64  TRP E CH2 1 
ATOM   3387 N N   . ILE C 3 14  ? 12.51472 3.64183   -20.67235 1.000 109.39059 ? 65  ILE E N   1 
ATOM   3388 C CA  . ILE C 3 14  ? 12.82870 2.22302   -20.54969 1.000 110.63011 ? 65  ILE E CA  1 
ATOM   3389 C C   . ILE C 3 14  ? 13.18868 1.83451   -19.11530 1.000 116.18645 ? 65  ILE E C   1 
ATOM   3390 O O   . ILE C 3 14  ? 12.98842 0.68037   -18.72304 1.000 117.65074 ? 65  ILE E O   1 
ATOM   3391 C CB  . ILE C 3 14  ? 13.94691 1.83189   -21.53468 1.000 112.47616 ? 65  ILE E CB  1 
ATOM   3392 C CG1 . ILE C 3 14  ? 13.77365 0.37982   -21.98601 1.000 113.56349 ? 65  ILE E CG1 1 
ATOM   3393 C CG2 . ILE C 3 14  ? 15.32633 2.04391   -20.92417 1.000 103.61732 ? 65  ILE E CG2 1 
ATOM   3394 C CD1 . ILE C 3 14  ? 12.56593 0.15507   -22.86849 1.000 120.21471 ? 65  ILE E CD1 1 
ATOM   3395 N N   . LEU C 3 15  ? 13.71535 2.76895   -18.31778 1.000 115.94554 ? 66  LEU E N   1 
ATOM   3396 C CA  . LEU C 3 15  ? 13.98566 2.47270   -16.91496 1.000 93.84702  ? 66  LEU E CA  1 
ATOM   3397 C C   . LEU C 3 15  ? 12.71813 2.50588   -16.07314 1.000 93.82072  ? 66  LEU E C   1 
ATOM   3398 O O   . LEU C 3 15  ? 12.63225 1.79991   -15.06253 1.000 96.32209  ? 66  LEU E O   1 
ATOM   3399 C CB  . LEU C 3 15  ? 15.01312 3.45358   -16.34703 1.000 80.11049  ? 66  LEU E CB  1 
ATOM   3400 C CG  . LEU C 3 15  ? 16.47462 3.21302   -16.73160 1.000 95.21386  ? 66  LEU E CG  1 
ATOM   3401 C CD1 . LEU C 3 15  ? 17.37964 4.24575   -16.07674 1.000 91.20543  ? 66  LEU E CD1 1 
ATOM   3402 C CD2 . LEU C 3 15  ? 16.90751 1.80261   -16.36369 1.000 90.99522  ? 66  LEU E CD2 1 
ATOM   3403 N N   . GLY C 3 16  ? 11.73579 3.31279   -16.46533 1.000 105.36548 ? 67  GLY E N   1 
ATOM   3404 C CA  . GLY C 3 16  ? 10.49804 3.41481   -15.71991 1.000 106.11987 ? 67  GLY E CA  1 
ATOM   3405 C C   . GLY C 3 16  ? 10.45842 4.61598   -14.79935 1.000 105.93573 ? 67  GLY E C   1 
ATOM   3406 O O   . GLY C 3 16  ? 9.99895  4.51213   -13.65843 1.000 109.07380 ? 67  GLY E O   1 
ATOM   3407 N N   . ASN C 3 17  ? 10.93277 5.75901   -15.28635 1.000 101.67528 ? 68  ASN E N   1 
ATOM   3408 C CA  . ASN C 3 17  ? 10.96058 6.96179   -14.46841 1.000 103.77606 ? 68  ASN E CA  1 
ATOM   3409 C C   . ASN C 3 17  ? 9.54028  7.33527   -14.04943 1.000 118.52877 ? 68  ASN E C   1 
ATOM   3410 O O   . ASN C 3 17  ? 8.60662  7.21979   -14.85196 1.000 116.19681 ? 68  ASN E O   1 
ATOM   3411 C CB  . ASN C 3 17  ? 11.60896 8.11502   -15.23634 1.000 106.47441 ? 68  ASN E CB  1 
ATOM   3412 C CG  . ASN C 3 17  ? 11.64580 9.40419   -14.43797 1.000 119.02239 ? 68  ASN E CG  1 
ATOM   3413 O OD1 . ASN C 3 17  ? 10.65477 10.13039  -14.35963 1.000 123.68424 ? 68  ASN E OD1 1 
ATOM   3414 N ND2 . ASN C 3 17  ? 12.79614 9.69784   -13.84481 1.000 113.86309 ? 68  ASN E ND2 1 
ATOM   3415 N N   . PRO C 3 18  ? 9.33912  7.77086   -12.80158 1.000 122.57968 ? 69  PRO E N   1 
ATOM   3416 C CA  . PRO C 3 18  ? 7.96560  8.00481   -12.32147 1.000 121.79477 ? 69  PRO E CA  1 
ATOM   3417 C C   . PRO C 3 18  ? 7.16991  8.98187   -13.17006 1.000 125.16005 ? 69  PRO E C   1 
ATOM   3418 O O   . PRO C 3 18  ? 5.95899  8.79638   -13.34457 1.000 131.19897 ? 69  PRO E O   1 
ATOM   3419 C CB  . PRO C 3 18  ? 8.19314  8.53978   -10.90288 1.000 120.51847 ? 69  PRO E CB  1 
ATOM   3420 C CG  . PRO C 3 18  ? 9.46312  7.89397   -10.47294 1.000 112.60754 ? 69  PRO E CG  1 
ATOM   3421 C CD  . PRO C 3 18  ? 10.32503 7.84413   -11.70866 1.000 110.19798 ? 69  PRO E CD  1 
ATOM   3422 N N   . GLU C 3 19  ? 7.81195  10.01957  -13.70370 1.000 126.83985 ? 70  GLU E N   1 
ATOM   3423 C CA  . GLU C 3 19  ? 7.11132  11.00471  -14.51613 1.000 145.78652 ? 70  GLU E CA  1 
ATOM   3424 C C   . GLU C 3 19  ? 7.04732  10.63291  -15.99182 1.000 149.64287 ? 70  GLU E C   1 
ATOM   3425 O O   . GLU C 3 19  ? 6.20057  11.17149  -16.71426 1.000 146.81595 ? 70  GLU E O   1 
ATOM   3426 C CB  . GLU C 3 19  ? 7.77753  12.37739  -14.36990 1.000 149.33948 ? 70  GLU E CB  1 
ATOM   3427 C CG  . GLU C 3 19  ? 8.03421  12.79656  -12.92880 1.000 148.94174 ? 70  GLU E CG  1 
ATOM   3428 C CD  . GLU C 3 19  ? 6.77279  13.22886  -12.20378 1.000 140.56289 ? 70  GLU E CD  1 
ATOM   3429 O OE1 . GLU C 3 19  ? 5.72977  13.40866  -12.86728 1.000 147.37585 ? 70  GLU E OE1 1 
ATOM   3430 O OE2 . GLU C 3 19  ? 6.82555  13.38985  -10.96631 1.000 133.12608 ? 70  GLU E OE2 1 
ATOM   3431 N N   . CYS C 3 20  ? 7.91553  9.73010   -16.45518 1.000 147.98407 ? 71  CYS E N   1 
ATOM   3432 C CA  . CYS C 3 20  ? 7.95426  9.40142   -17.87744 1.000 140.26207 ? 71  CYS E CA  1 
ATOM   3433 C C   . CYS C 3 20  ? 6.77303  8.52845   -18.28686 1.000 157.11852 ? 71  CYS E C   1 
ATOM   3434 O O   . CYS C 3 20  ? 6.16574  8.75283   -19.34052 1.000 169.18614 ? 71  CYS E O   1 
ATOM   3435 C CB  . CYS C 3 20  ? 9.27287  8.70709   -18.21783 1.000 135.81679 ? 71  CYS E CB  1 
ATOM   3436 S SG  . CYS C 3 20  ? 10.71849 9.79387   -18.23251 1.000 138.52088 ? 71  CYS E SG  1 
ATOM   3437 N N   . GLU C 3 21  ? 6.43391  7.52719   -17.46999 1.000 158.65698 ? 72  GLU E N   1 
ATOM   3438 C CA  . GLU C 3 21  ? 5.38637  6.57810   -17.83452 1.000 162.73412 ? 72  GLU E CA  1 
ATOM   3439 C C   . GLU C 3 21  ? 4.00116  7.20945   -17.87933 1.000 172.15967 ? 72  GLU E C   1 
ATOM   3440 O O   . GLU C 3 21  ? 3.10797  6.66144   -18.53430 1.000 182.28600 ? 72  GLU E O   1 
ATOM   3441 C CB  . GLU C 3 21  ? 5.38373  5.39669   -16.86102 1.000 156.14167 ? 72  GLU E CB  1 
ATOM   3442 C CG  . GLU C 3 21  ? 6.25453  4.21575   -17.28336 1.000 155.69004 ? 72  GLU E CG  1 
ATOM   3443 C CD  . GLU C 3 21  ? 7.68940  4.59923   -17.60093 1.000 146.59682 ? 72  GLU E CD  1 
ATOM   3444 O OE1 . GLU C 3 21  ? 8.20916  5.56304   -17.00186 1.000 155.91914 ? 72  GLU E OE1 1 
ATOM   3445 O OE2 . GLU C 3 21  ? 8.30138  3.92883   -18.45758 1.000 114.41050 ? 72  GLU E OE2 1 
ATOM   3446 N N   . SER C 3 22  ? 3.79830  8.34151   -17.20403 1.000 172.89924 ? 73  SER E N   1 
ATOM   3447 C CA  . SER C 3 22  ? 2.49109  8.98627   -17.20475 1.000 183.11591 ? 73  SER E CA  1 
ATOM   3448 C C   . SER C 3 22  ? 2.14338  9.62294   -18.54376 1.000 183.47899 ? 73  SER E C   1 
ATOM   3449 O O   . SER C 3 22  ? 0.98287  9.99555   -18.74709 1.000 181.60595 ? 73  SER E O   1 
ATOM   3450 C CB  . SER C 3 22  ? 2.42752  10.04361  -16.10092 1.000 170.66434 ? 73  SER E CB  1 
ATOM   3451 O OG  . SER C 3 22  ? 2.80936  9.49831   -14.85031 1.000 157.88393 ? 73  SER E OG  1 
ATOM   3452 N N   . LEU C 3 23  ? 3.10684  9.75635   -19.45517 1.000 184.09363 ? 74  LEU E N   1 
ATOM   3453 C CA  . LEU C 3 23  ? 2.86855  10.44423  -20.72024 1.000 182.78238 ? 74  LEU E CA  1 
ATOM   3454 C C   . LEU C 3 23  ? 2.50147  9.48087   -21.84742 1.000 191.27982 ? 74  LEU E C   1 
ATOM   3455 O O   . LEU C 3 23  ? 1.41448  9.58108   -22.42513 1.000 193.39567 ? 74  LEU E O   1 
ATOM   3456 C CB  . LEU C 3 23  ? 4.10062  11.27244  -21.10230 1.000 172.96506 ? 74  LEU E CB  1 
ATOM   3457 C CG  . LEU C 3 23  ? 4.45064  12.41582  -20.14858 1.000 174.02923 ? 74  LEU E CG  1 
ATOM   3458 C CD1 . LEU C 3 23  ? 5.91095  12.80976  -20.29003 1.000 162.38297 ? 74  LEU E CD1 1 
ATOM   3459 C CD2 . LEU C 3 23  ? 3.54335  13.61127  -20.39684 1.000 164.99335 ? 74  LEU E CD2 1 
ATOM   3460 N N   . PHE C 3 24  ? 3.39171  8.54339   -22.17023 1.000 190.09381 ? 75  PHE E N   1 
ATOM   3461 C CA  . PHE C 3 24  ? 3.21281  7.71815   -23.35541 1.000 191.05313 ? 75  PHE E CA  1 
ATOM   3462 C C   . PHE C 3 24  ? 3.64615  6.28189   -23.10300 1.000 190.46837 ? 75  PHE E C   1 
ATOM   3463 O O   . PHE C 3 24  ? 4.54121  6.00890   -22.29869 1.000 178.11061 ? 75  PHE E O   1 
ATOM   3464 C CB  . PHE C 3 24  ? 3.99850  8.27367   -24.55207 1.000 187.62699 ? 75  PHE E CB  1 
ATOM   3465 C CG  . PHE C 3 24  ? 3.34277  9.44812   -25.21766 1.000 183.67512 ? 75  PHE E CG  1 
ATOM   3466 C CD1 . PHE C 3 24  ? 2.36362  9.25698   -26.17839 1.000 181.57926 ? 75  PHE E CD1 1 
ATOM   3467 C CD2 . PHE C 3 24  ? 3.70840  10.74247  -24.88829 1.000 183.39532 ? 75  PHE E CD2 1 
ATOM   3468 C CE1 . PHE C 3 24  ? 1.75855  10.33482  -26.79570 1.000 180.18076 ? 75  PHE E CE1 1 
ATOM   3469 C CE2 . PHE C 3 24  ? 3.10709  11.82478  -25.50207 1.000 173.40270 ? 75  PHE E CE2 1 
ATOM   3470 C CZ  . PHE C 3 24  ? 2.13081  11.62035  -26.45703 1.000 172.04380 ? 75  PHE E CZ  1 
ATOM   3471 N N   . SER C 3 25  ? 2.98527  5.36994   -23.81228 1.000 194.50040 ? 76  SER E N   1 
ATOM   3472 C CA  . SER C 3 25  ? 3.41393  3.98924   -23.96923 1.000 189.83569 ? 76  SER E CA  1 
ATOM   3473 C C   . SER C 3 25  ? 3.02998  3.55505   -25.37601 1.000 183.16456 ? 76  SER E C   1 
ATOM   3474 O O   . SER C 3 25  ? 2.14088  4.14086   -25.99789 1.000 174.74593 ? 76  SER E O   1 
ATOM   3475 C CB  . SER C 3 25  ? 2.78365  3.06439   -22.91788 1.000 172.07970 ? 76  SER E CB  1 
ATOM   3476 O OG  . SER C 3 25  ? 1.37266  3.03131   -23.04427 1.000 174.75267 ? 76  SER E OG  1 
ATOM   3477 N N   . LYS C 3 26  ? 3.71774  2.53804   -25.88917 1.000 178.88778 ? 77  LYS E N   1 
ATOM   3478 C CA  . LYS C 3 26  ? 3.45915  2.08959   -27.25165 1.000 173.40503 ? 77  LYS E CA  1 
ATOM   3479 C C   . LYS C 3 26  ? 4.02469  0.68943   -27.44057 1.000 167.06125 ? 77  LYS E C   1 
ATOM   3480 O O   . LYS C 3 26  ? 4.81873  0.19965   -26.63383 1.000 159.77897 ? 77  LYS E O   1 
ATOM   3481 C CB  . LYS C 3 26  ? 4.05006  3.05997   -28.28021 1.000 174.00029 ? 77  LYS E CB  1 
ATOM   3482 C CG  . LYS C 3 26  ? 3.27942  3.12334   -29.58936 1.000 170.93503 ? 77  LYS E CG  1 
ATOM   3483 C CD  . LYS C 3 26  ? 3.73269  4.29555   -30.44231 1.000 169.40810 ? 77  LYS E CD  1 
ATOM   3484 C CE  . LYS C 3 26  ? 2.77317  4.53861   -31.59509 1.000 165.84874 ? 77  LYS E CE  1 
ATOM   3485 N NZ  . LYS C 3 26  ? 3.09413  5.79215   -32.33060 1.000 162.49259 ? 77  LYS E NZ  1 
ATOM   3486 N N   . GLU C 3 27  ? 3.59353  0.04965   -28.52679 1.000 167.46277 ? 78  GLU E N   1 
ATOM   3487 C CA  . GLU C 3 27  ? 4.04009  -1.28711  -28.89744 1.000 162.91377 ? 78  GLU E CA  1 
ATOM   3488 C C   . GLU C 3 27  ? 4.71734  -1.31901  -30.25758 1.000 160.26799 ? 78  GLU E C   1 
ATOM   3489 O O   . GLU C 3 27  ? 5.78383  -1.92827  -30.40054 1.000 156.52089 ? 78  GLU E O   1 
ATOM   3490 C CB  . GLU C 3 27  ? 2.84872  -2.25562  -28.87818 1.000 157.65236 ? 78  GLU E CB  1 
ATOM   3491 C CG  . GLU C 3 27  ? 2.12377  -2.28567  -27.54857 1.000 167.94787 ? 78  GLU E CG  1 
ATOM   3492 C CD  . GLU C 3 27  ? 0.62168  -2.35031  -27.70652 1.000 173.37563 ? 78  GLU E CD  1 
ATOM   3493 O OE1 . GLU C 3 27  ? 0.12745  -2.13171  -28.83262 1.000 174.76396 ? 78  GLU E OE1 1 
ATOM   3494 O OE2 . GLU C 3 27  ? -0.06500 -2.60497  -26.69799 1.000 169.18571 ? 78  GLU E OE2 1 
ATOM   3495 N N   . SER C 3 28  ? 4.12801  -0.68277  -31.26567 1.000 167.05216 ? 79  SER E N   1 
ATOM   3496 C CA  . SER C 3 28  ? 4.68779  -0.63952  -32.61054 1.000 164.33768 ? 79  SER E CA  1 
ATOM   3497 C C   . SER C 3 28  ? 5.14967  0.78056   -32.90632 1.000 163.62765 ? 79  SER E C   1 
ATOM   3498 O O   . SER C 3 28  ? 4.35376  1.72323   -32.83267 1.000 169.77972 ? 79  SER E O   1 
ATOM   3499 C CB  . SER C 3 28  ? 3.66155  -1.09951  -33.64643 1.000 160.60886 ? 79  SER E CB  1 
ATOM   3500 O OG  . SER C 3 28  ? 2.47928  -0.32109  -33.57598 1.000 165.32476 ? 79  SER E OG  1 
ATOM   3501 N N   . TRP C 3 29  ? 6.42923  0.92939   -33.24136 1.000 160.50482 ? 80  TRP E N   1 
ATOM   3502 C CA  . TRP C 3 29  ? 6.98203  2.23619   -33.56755 1.000 170.06501 ? 80  TRP E CA  1 
ATOM   3503 C C   . TRP C 3 29  ? 8.21910  2.04930   -34.43300 1.000 166.61340 ? 80  TRP E C   1 
ATOM   3504 O O   . TRP C 3 29  ? 8.79028  0.95829   -34.50666 1.000 164.65362 ? 80  TRP E O   1 
ATOM   3505 C CB  . TRP C 3 29  ? 7.31241  3.04221   -32.30352 1.000 173.54380 ? 80  TRP E CB  1 
ATOM   3506 C CG  . TRP C 3 29  ? 8.61338  2.67299   -31.64640 1.000 166.40822 ? 80  TRP E CG  1 
ATOM   3507 C CD1 . TRP C 3 29  ? 9.86164  3.11283   -31.98651 1.000 163.74924 ? 80  TRP E CD1 1 
ATOM   3508 C CD2 . TRP C 3 29  ? 8.78980  1.79748   -30.52613 1.000 159.57260 ? 80  TRP E CD2 1 
ATOM   3509 N NE1 . TRP C 3 29  ? 10.80223 2.55929   -31.15310 1.000 150.43125 ? 80  TRP E NE1 1 
ATOM   3510 C CE2 . TRP C 3 29  ? 10.17035 1.74902   -30.24700 1.000 155.93379 ? 80  TRP E CE2 1 
ATOM   3511 C CE3 . TRP C 3 29  ? 7.91481  1.04799   -29.73379 1.000 161.86407 ? 80  TRP E CE3 1 
ATOM   3512 C CZ2 . TRP C 3 29  ? 10.69559 0.98156   -29.21026 1.000 155.81043 ? 80  TRP E CZ2 1 
ATOM   3513 C CZ3 . TRP C 3 29  ? 8.43870  0.28661   -28.70498 1.000 156.33951 ? 80  TRP E CZ3 1 
ATOM   3514 C CH2 . TRP C 3 29  ? 9.81586  0.25979   -28.45247 1.000 151.56803 ? 80  TRP E CH2 1 
ATOM   3515 N N   . SER C 3 30  ? 8.62383  3.13688   -35.08973 1.000 167.68405 ? 81  SER E N   1 
ATOM   3516 C CA  . SER C 3 30  ? 9.81230  3.13874   -35.93454 1.000 169.16545 ? 81  SER E CA  1 
ATOM   3517 C C   . SER C 3 30  ? 10.78832 4.26754   -35.63560 1.000 174.16079 ? 81  SER E C   1 
ATOM   3518 O O   . SER C 3 30  ? 11.93582 4.19428   -36.09198 1.000 167.30312 ? 81  SER E O   1 
ATOM   3519 C CB  . SER C 3 30  ? 9.41779  3.21055   -37.41823 1.000 161.59904 ? 81  SER E CB  1 
ATOM   3520 O OG  . SER C 3 30  ? 8.71845  2.04500   -37.81918 1.000 144.19989 ? 81  SER E OG  1 
ATOM   3521 N N   . TYR C 3 31  ? 10.38444 5.29903   -34.89644 1.000 175.73921 ? 82  TYR E N   1 
ATOM   3522 C CA  . TYR C 3 31  ? 11.25405 6.41184   -34.54273 1.000 180.15582 ? 82  TYR E CA  1 
ATOM   3523 C C   . TYR C 3 31  ? 11.24035 6.58774   -33.03177 1.000 169.36709 ? 82  TYR E C   1 
ATOM   3524 O O   . TYR C 3 31  ? 10.17860 6.53485   -32.40476 1.000 165.12441 ? 82  TYR E O   1 
ATOM   3525 C CB  . TYR C 3 31  ? 10.80856 7.70253   -35.24003 1.000 184.43395 ? 82  TYR E CB  1 
ATOM   3526 C CG  . TYR C 3 31  ? 10.43915 7.50331   -36.69396 1.000 169.89803 ? 82  TYR E CG  1 
ATOM   3527 C CD1 . TYR C 3 31  ? 11.40593 7.18438   -37.63901 1.000 168.93212 ? 82  TYR E CD1 1 
ATOM   3528 C CD2 . TYR C 3 31  ? 9.12239  7.62320   -37.11930 1.000 170.41622 ? 82  TYR E CD2 1 
ATOM   3529 C CE1 . TYR C 3 31  ? 11.07275 6.99745   -38.96801 1.000 177.84805 ? 82  TYR E CE1 1 
ATOM   3530 C CE2 . TYR C 3 31  ? 8.77952  7.43775   -38.44602 1.000 179.57957 ? 82  TYR E CE2 1 
ATOM   3531 C CZ  . TYR C 3 31  ? 9.75864  7.12517   -39.36556 1.000 179.07255 ? 82  TYR E CZ  1 
ATOM   3532 O OH  . TYR C 3 31  ? 9.42324  6.93968   -40.68710 1.000 165.75238 ? 82  TYR E OH  1 
ATOM   3533 N N   . ILE C 3 32  ? 12.42020 6.79973   -32.44895 1.000 169.08090 ? 83  ILE E N   1 
ATOM   3534 C CA  . ILE C 3 32  ? 12.56283 6.75354   -30.99729 1.000 169.83605 ? 83  ILE E CA  1 
ATOM   3535 C C   . ILE C 3 32  ? 13.32025 7.96571   -30.46579 1.000 174.82683 ? 83  ILE E C   1 
ATOM   3536 O O   . ILE C 3 32  ? 13.32294 8.22392   -29.25678 1.000 185.52715 ? 83  ILE E O   1 
ATOM   3537 C CB  . ILE C 3 32  ? 13.25540 5.44540   -30.57027 1.000 164.57971 ? 83  ILE E CB  1 
ATOM   3538 C CG1 . ILE C 3 32  ? 12.83021 5.04570   -29.15632 1.000 174.73964 ? 83  ILE E CG1 1 
ATOM   3539 C CG2 . ILE C 3 32  ? 14.76905 5.57810   -30.67120 1.000 151.45950 ? 83  ILE E CG2 1 
ATOM   3540 C CD1 . ILE C 3 32  ? 13.20803 3.62916   -28.78914 1.000 158.41850 ? 83  ILE E CD1 1 
ATOM   3541 N N   . ALA C 3 33  ? 13.96181 8.72035   -31.35482 1.000 170.62302 ? 84  ALA E N   1 
ATOM   3542 C CA  . ALA C 3 33  ? 14.81771 9.82960   -30.94160 1.000 176.14228 ? 84  ALA E CA  1 
ATOM   3543 C C   . ALA C 3 33  ? 13.95671 11.04085  -30.60027 1.000 187.66038 ? 84  ALA E C   1 
ATOM   3544 O O   . ALA C 3 33  ? 13.40182 11.68828  -31.49420 1.000 182.81113 ? 84  ALA E O   1 
ATOM   3545 C CB  . ALA C 3 33  ? 15.82231 10.16285  -32.04051 1.000 171.46010 ? 84  ALA E CB  1 
ATOM   3546 N N   . GLU C 3 34  ? 13.84116 11.35061  -29.30657 1.000 199.38456 ? 85  GLU E N   1 
ATOM   3547 C CA  . GLU C 3 34  ? 13.08512 12.51634  -28.85769 1.000 193.69613 ? 85  GLU E CA  1 
ATOM   3548 C C   . GLU C 3 34  ? 13.96771 13.55220  -28.17315 1.000 188.64653 ? 85  GLU E C   1 
ATOM   3549 O O   . GLU C 3 34  ? 14.02124 14.70001  -28.62663 1.000 194.53320 ? 85  GLU E O   1 
ATOM   3550 C CB  . GLU C 3 34  ? 11.95068 12.07453  -27.92335 1.000 187.57241 ? 85  GLU E CB  1 
ATOM   3551 C CG  . GLU C 3 34  ? 10.91901 11.17528  -28.58326 1.000 187.38468 ? 85  GLU E CG  1 
ATOM   3552 C CD  . GLU C 3 34  ? 10.13953 11.88632  -29.67140 1.000 190.05239 ? 85  GLU E CD  1 
ATOM   3553 O OE1 . GLU C 3 34  ? 9.69837  13.03100  -29.43671 1.000 190.59679 ? 85  GLU E OE1 1 
ATOM   3554 O OE2 . GLU C 3 34  ? 9.96846  11.30102  -30.76137 1.000 189.21791 ? 85  GLU E OE2 1 
ATOM   3555 N N   . THR C 3 35  ? 14.67252 13.18344  -27.09750 1.000 182.23956 ? 86  THR E N   1 
ATOM   3556 C CA  . THR C 3 35  ? 15.53227 14.10459  -26.34887 1.000 188.03295 ? 86  THR E CA  1 
ATOM   3557 C C   . THR C 3 35  ? 16.75372 13.32100  -25.87796 1.000 191.07837 ? 86  THR E C   1 
ATOM   3558 O O   . THR C 3 35  ? 16.60063 12.23256  -25.29356 1.000 185.53756 ? 86  THR E O   1 
ATOM   3559 C CB  . THR C 3 35  ? 14.82114 14.74412  -25.14891 1.000 185.86581 ? 86  THR E CB  1 
ATOM   3560 O OG1 . THR C 3 35  ? 14.28184 13.71986  -24.30476 1.000 193.78324 ? 86  THR E OG1 1 
ATOM   3561 C CG2 . THR C 3 35  ? 13.70271 15.67898  -25.59913 1.000 181.50998 ? 86  THR E CG2 1 
ATOM   3562 N N   . PRO C 3 36  ? 17.96749 13.83061  -26.11424 1.000 198.75071 ? 87  PRO E N   1 
ATOM   3563 C CA  . PRO C 3 36  ? 19.17400 13.06188  -25.77201 1.000 196.01121 ? 87  PRO E CA  1 
ATOM   3564 C C   . PRO C 3 36  ? 19.38947 12.84815  -24.27943 1.000 195.11002 ? 87  PRO E C   1 
ATOM   3565 O O   . PRO C 3 36  ? 19.50590 11.70252  -23.83228 1.000 189.00537 ? 87  PRO E O   1 
ATOM   3566 C CB  . PRO C 3 36  ? 20.30337 13.90645  -26.37789 1.000 200.04548 ? 87  PRO E CB  1 
ATOM   3567 C CG  . PRO C 3 36  ? 19.74441 15.29123  -26.44198 1.000 204.74174 ? 87  PRO E CG  1 
ATOM   3568 C CD  . PRO C 3 36  ? 18.29169 15.11152  -26.76425 1.000 204.01646 ? 87  PRO E CD  1 
ATOM   3569 N N   . ASN C 3 37  ? 19.43391 13.92222  -23.50011 1.000 195.88551 ? 88  ASN E N   1 
ATOM   3570 C CA  . ASN C 3 37  ? 19.80857 13.84008  -22.08847 1.000 198.27469 ? 88  ASN E CA  1 
ATOM   3571 C C   . ASN C 3 37  ? 19.46887 15.16942  -21.42122 1.000 200.08341 ? 88  ASN E C   1 
ATOM   3572 O O   . ASN C 3 37  ? 18.84597 16.04718  -22.03116 1.000 193.58597 ? 88  ASN E O   1 
ATOM   3573 C CB  . ASN C 3 37  ? 21.28910 13.48780  -21.92871 1.000 195.97658 ? 88  ASN E CB  1 
ATOM   3574 C CG  . ASN C 3 37  ? 22.20467 14.50161  -22.58804 1.000 199.60899 ? 88  ASN E CG  1 
ATOM   3575 O OD1 . ASN C 3 37  ? 21.76463 15.32560  -23.39018 1.000 205.60938 ? 88  ASN E OD1 1 
ATOM   3576 N ND2 . ASN C 3 37  ? 23.48750 14.44668  -22.24985 1.000 190.90372 ? 88  ASN E ND2 1 
ATOM   3577 N N   . SER C 3 38  ? 19.89842 15.31724  -20.16370 1.000 201.42901 ? 89  SER E N   1 
ATOM   3578 C CA  . SER C 3 38  ? 19.61259 16.49839  -19.34406 1.000 195.55216 ? 89  SER E CA  1 
ATOM   3579 C C   . SER C 3 38  ? 18.10770 16.71262  -19.18474 1.000 197.46753 ? 89  SER E C   1 
ATOM   3580 O O   . SER C 3 38  ? 17.61661 17.84308  -19.18622 1.000 206.34963 ? 89  SER E O   1 
ATOM   3581 C CB  . SER C 3 38  ? 20.29413 17.75002  -19.90876 1.000 198.38839 ? 89  SER E CB  1 
ATOM   3582 O OG  . SER C 3 38  ? 19.69962 18.16387  -21.12639 1.000 196.97354 ? 89  SER E OG  1 
ATOM   3583 N N   . GLU C 3 39  ? 17.37260 15.61647  -19.03418 1.000 190.57104 ? 90  GLU E N   1 
ATOM   3584 C CA  . GLU C 3 39  ? 15.92162 15.65505  -18.86493 1.000 185.87973 ? 90  GLU E CA  1 
ATOM   3585 C C   . GLU C 3 39  ? 15.53646 14.62003  -17.81054 1.000 181.54825 ? 90  GLU E C   1 
ATOM   3586 O O   . GLU C 3 39  ? 16.36963 14.15817  -17.02229 1.000 173.12959 ? 90  GLU E O   1 
ATOM   3587 C CB  . GLU C 3 39  ? 15.19356 15.42769  -20.20051 1.000 188.05031 ? 90  GLU E CB  1 
ATOM   3588 C CG  . GLU C 3 39  ? 15.78635 16.12437  -21.41352 1.000 198.53484 ? 90  GLU E CG  1 
ATOM   3589 C CD  . GLU C 3 39  ? 15.49778 17.61969  -21.44001 1.000 204.41545 ? 90  GLU E CD  1 
ATOM   3590 O OE1 . GLU C 3 39  ? 14.44164 18.03600  -20.91819 1.000 207.25104 ? 90  GLU E OE1 1 
ATOM   3591 O OE2 . GLU C 3 39  ? 16.32746 18.38065  -21.98530 1.000 195.09001 ? 90  GLU E OE2 1 
ATOM   3592 N N   . ASN C 3 40  ? 14.25228 14.25436  -17.78644 1.000 181.62759 ? 91  ASN E N   1 
ATOM   3593 C CA  . ASN C 3 40  ? 13.69858 13.35350  -16.77978 1.000 167.20033 ? 91  ASN E CA  1 
ATOM   3594 C C   . ASN C 3 40  ? 14.21095 11.92259  -16.91268 1.000 149.87288 ? 91  ASN E C   1 
ATOM   3595 O O   . ASN C 3 40  ? 13.72618 11.02622  -16.21449 1.000 144.67217 ? 91  ASN E O   1 
ATOM   3596 C CB  . ASN C 3 40  ? 12.16770 13.35590  -16.85480 1.000 165.65657 ? 91  ASN E CB  1 
ATOM   3597 C CG  . ASN C 3 40  ? 11.56245 14.64526  -16.33317 1.000 172.22980 ? 91  ASN E CG  1 
ATOM   3598 O OD1 . ASN C 3 40  ? 12.27544 15.61973  -16.09216 1.000 169.54679 ? 91  ASN E OD1 1 
ATOM   3599 N ND2 . ASN C 3 40  ? 10.24576 14.65447  -16.14319 1.000 168.43786 ? 91  ASN E ND2 1 
ATOM   3600 N N   . GLY C 3 41  ? 15.15660 11.69403  -17.82214 1.000 151.43529 ? 92  GLY E N   1 
ATOM   3601 C CA  . GLY C 3 41  ? 15.69627 10.37099  -18.07135 1.000 137.49465 ? 92  GLY E CA  1 
ATOM   3602 C C   . GLY C 3 41  ? 16.14508 9.62035   -16.83375 1.000 137.39166 ? 92  GLY E C   1 
ATOM   3603 O O   . GLY C 3 41  ? 15.53492 8.61351   -16.46323 1.000 130.47120 ? 92  GLY E O   1 
ATOM   3604 N N   . THR C 3 42  ? 17.20038 10.09332  -16.17994 1.000 133.67913 ? 93  THR E N   1 
ATOM   3605 C CA  . THR C 3 42  ? 17.74543 9.43850   -14.99291 1.000 113.63782 ? 93  THR E CA  1 
ATOM   3606 C C   . THR C 3 42  ? 17.42241 10.29170  -13.77022 1.000 126.02822 ? 93  THR E C   1 
ATOM   3607 O O   . THR C 3 42  ? 18.05092 11.32891  -13.54039 1.000 129.98512 ? 93  THR E O   1 
ATOM   3608 C CB  . THR C 3 42  ? 19.24913 9.21753   -15.13050 1.000 102.25750 ? 93  THR E CB  1 
ATOM   3609 O OG1 . THR C 3 42  ? 19.89621 10.46588  -15.41298 1.000 126.40830 ? 93  THR E OG1 1 
ATOM   3610 C CG2 . THR C 3 42  ? 19.54123 8.23076   -16.25210 1.000 95.36468  ? 93  THR E CG2 1 
ATOM   3611 N N   . CYS C 3 43  ? 16.44122 9.84663   -12.98218 1.000 117.27304 ? 94  CYS E N   1 
ATOM   3612 C CA  . CYS C 3 43  ? 16.13516 10.52390  -11.72863 1.000 112.18338 ? 94  CYS E CA  1 
ATOM   3613 C C   . CYS C 3 43  ? 17.16629 10.22176  -10.64932 1.000 116.76018 ? 94  CYS E C   1 
ATOM   3614 O O   . CYS C 3 43  ? 17.23805 10.95123  -9.65466  1.000 115.48110 ? 94  CYS E O   1 
ATOM   3615 C CB  . CYS C 3 43  ? 14.73534 10.13774  -11.24990 1.000 114.50408 ? 94  CYS E CB  1 
ATOM   3616 S SG  . CYS C 3 43  ? 14.51184 8.37690   -10.92369 1.000 110.62604 ? 94  CYS E SG  1 
ATOM   3617 N N   . TYR C 3 44  ? 17.96254 9.17002   -10.82442 1.000 109.76569 ? 95  TYR E N   1 
ATOM   3618 C CA  . TYR C 3 44  ? 19.06540 8.85170   -9.93881  1.000 104.41481 ? 95  TYR E CA  1 
ATOM   3619 C C   . TYR C 3 44  ? 20.36842 8.90105   -10.72445 1.000 110.07143 ? 95  TYR E C   1 
ATOM   3620 O O   . TYR C 3 44  ? 20.43925 8.34229   -11.82880 1.000 108.70392 ? 95  TYR E O   1 
ATOM   3621 C CB  . TYR C 3 44  ? 18.88620 7.46097   -9.30539  1.000 86.81952  ? 95  TYR E CB  1 
ATOM   3622 C CG  . TYR C 3 44  ? 19.61415 7.28756   -7.99087  1.000 100.58098 ? 95  TYR E CG  1 
ATOM   3623 C CD1 . TYR C 3 44  ? 20.96149 6.95045   -7.96063  1.000 100.93543 ? 95  TYR E CD1 1 
ATOM   3624 C CD2 . TYR C 3 44  ? 18.95521 7.46110   -6.78048  1.000 112.43872 ? 95  TYR E CD2 1 
ATOM   3625 C CE1 . TYR C 3 44  ? 21.63233 6.79212   -6.76274  1.000 97.68842  ? 95  TYR E CE1 1 
ATOM   3626 C CE2 . TYR C 3 44  ? 19.61790 7.30401   -5.57667  1.000 89.05791  ? 95  TYR E CE2 1 
ATOM   3627 C CZ  . TYR C 3 44  ? 20.95618 6.96908   -5.57435  1.000 95.21080  ? 95  TYR E CZ  1 
ATOM   3628 O OH  . TYR C 3 44  ? 21.62166 6.81066   -4.38023  1.000 100.52612 ? 95  TYR E OH  1 
ATOM   3629 N N   . PRO C 3 45  ? 21.40503 9.56310   -10.21130 1.000 106.35316 ? 96  PRO E N   1 
ATOM   3630 C CA  . PRO C 3 45  ? 22.66624 9.65036   -10.95818 1.000 107.50855 ? 96  PRO E CA  1 
ATOM   3631 C C   . PRO C 3 45  ? 23.26436 8.27439   -11.21147 1.000 101.68552 ? 96  PRO E C   1 
ATOM   3632 O O   . PRO C 3 45  ? 23.19516 7.37872   -10.36745 1.000 108.61230 ? 96  PRO E O   1 
ATOM   3633 C CB  . PRO C 3 45  ? 23.56411 10.49577  -10.04554 1.000 107.25838 ? 96  PRO E CB  1 
ATOM   3634 C CG  . PRO C 3 45  ? 22.92037 10.43279  -8.69266  1.000 108.32646 ? 96  PRO E CG  1 
ATOM   3635 C CD  . PRO C 3 45  ? 21.45378 10.31982  -8.95060  1.000 97.65002  ? 96  PRO E CD  1 
ATOM   3636 N N   . GLY C 3 46  ? 23.85304 8.11575   -12.38898 1.000 111.07910 ? 97  GLY E N   1 
ATOM   3637 C CA  . GLY C 3 46  ? 24.45393 6.85181   -12.75939 1.000 105.05551 ? 97  GLY E CA  1 
ATOM   3638 C C   . GLY C 3 46  ? 24.84626 6.85499   -14.21976 1.000 117.72560 ? 97  GLY E C   1 
ATOM   3639 O O   . GLY C 3 46  ? 24.60415 7.81681   -14.95597 1.000 126.71755 ? 97  GLY E O   1 
ATOM   3640 N N   . TYR C 3 47  ? 25.46020 5.74823   -14.62611 1.000 121.84912 ? 98  TYR E N   1 
ATOM   3641 C CA  . TYR C 3 47  ? 25.93699 5.56032   -15.98910 1.000 106.10248 ? 98  TYR E CA  1 
ATOM   3642 C C   . TYR C 3 47  ? 25.14142 4.44848   -16.65781 1.000 111.13385 ? 98  TYR E C   1 
ATOM   3643 O O   . TYR C 3 47  ? 25.03209 3.34380   -16.11475 1.000 115.61723 ? 98  TYR E O   1 
ATOM   3644 C CB  . TYR C 3 47  ? 27.43137 5.22891   -16.00263 1.000 108.19383 ? 98  TYR E CB  1 
ATOM   3645 C CG  . TYR C 3 47  ? 27.89425 4.49777   -17.24321 1.000 126.30942 ? 98  TYR E CG  1 
ATOM   3646 C CD1 . TYR C 3 47  ? 27.91917 5.13134   -18.47968 1.000 121.78614 ? 98  TYR E CD1 1 
ATOM   3647 C CD2 . TYR C 3 47  ? 28.31123 3.17439   -17.17666 1.000 121.51329 ? 98  TYR E CD2 1 
ATOM   3648 C CE1 . TYR C 3 47  ? 28.34353 4.46612   -19.61516 1.000 99.99894  ? 98  TYR E CE1 1 
ATOM   3649 C CE2 . TYR C 3 47  ? 28.73730 2.50136   -18.30632 1.000 123.31760 ? 98  TYR E CE2 1 
ATOM   3650 C CZ  . TYR C 3 47  ? 28.75205 3.15187   -19.52218 1.000 119.28664 ? 98  TYR E CZ  1 
ATOM   3651 O OH  . TYR C 3 47  ? 29.17511 2.48399   -20.64865 1.000 137.15612 ? 98  TYR E OH  1 
ATOM   3652 N N   . PHE C 3 48  ? 24.59014 4.74327   -17.83259 1.000 114.10275 ? 99  PHE E N   1 
ATOM   3653 C CA  . PHE C 3 48  ? 23.84011 3.76451   -18.61226 1.000 103.69499 ? 99  PHE E CA  1 
ATOM   3654 C C   . PHE C 3 48  ? 24.79115 3.12198   -19.61487 1.000 99.14771  ? 99  PHE E C   1 
ATOM   3655 O O   . PHE C 3 48  ? 25.23753 3.77353   -20.56469 1.000 109.01563 ? 99  PHE E O   1 
ATOM   3656 C CB  . PHE C 3 48  ? 22.65634 4.42561   -19.31419 1.000 95.93014  ? 99  PHE E CB  1 
ATOM   3657 C CG  . PHE C 3 48  ? 21.52845 3.48160   -19.62727 1.000 95.49709  ? 99  PHE E CG  1 
ATOM   3658 C CD1 . PHE C 3 48  ? 21.71756 2.41014   -20.48549 1.000 90.14467  ? 99  PHE E CD1 1 
ATOM   3659 C CD2 . PHE C 3 48  ? 20.27781 3.66676   -19.06130 1.000 91.64847  ? 99  PHE E CD2 1 
ATOM   3660 C CE1 . PHE C 3 48  ? 20.68171 1.54295   -20.77367 1.000 84.49274  ? 99  PHE E CE1 1 
ATOM   3661 C CE2 . PHE C 3 48  ? 19.23719 2.80259   -19.34568 1.000 97.36598  ? 99  PHE E CE2 1 
ATOM   3662 C CZ  . PHE C 3 48  ? 19.43970 1.73941   -20.20300 1.000 97.29211  ? 99  PHE E CZ  1 
ATOM   3663 N N   . ALA C 3 49  ? 25.10300 1.84726   -19.40124 1.000 98.32216  ? 100 ALA E N   1 
ATOM   3664 C CA  . ALA C 3 49  ? 26.01914 1.14458   -20.28660 1.000 99.69159  ? 100 ALA E CA  1 
ATOM   3665 C C   . ALA C 3 49  ? 25.36641 0.87700   -21.63606 1.000 110.86068 ? 100 ALA E C   1 
ATOM   3666 O O   . ALA C 3 49  ? 24.19841 0.48468   -21.71217 1.000 113.48502 ? 100 ALA E O   1 
ATOM   3667 C CB  . ALA C 3 49  ? 26.46961 -0.17019  -19.65188 1.000 91.57708  ? 100 ALA E CB  1 
ATOM   3668 N N   . ASP C 3 50  ? 26.13618 1.09380   -22.70484 1.000 94.65143  ? 101 ASP E N   1 
ATOM   3669 C CA  . ASP C 3 50  ? 25.70717 0.79250   -24.07104 1.000 104.56406 ? 101 ASP E CA  1 
ATOM   3670 C C   . ASP C 3 50  ? 24.40768 1.51822   -24.41994 1.000 111.23772 ? 101 ASP E C   1 
ATOM   3671 O O   . ASP C 3 50  ? 23.47648 0.93957   -24.98397 1.000 115.16345 ? 101 ASP E O   1 
ATOM   3672 C CB  . ASP C 3 50  ? 25.56463 -0.71810  -24.27267 1.000 94.06344  ? 101 ASP E CB  1 
ATOM   3673 C CG  . ASP C 3 50  ? 26.74064 -1.49284  -23.71070 1.000 93.42050  ? 101 ASP E CG  1 
ATOM   3674 O OD1 . ASP C 3 50  ? 27.86926 -0.95776  -23.72537 1.000 101.39356 ? 101 ASP E OD1 1 
ATOM   3675 O OD2 . ASP C 3 50  ? 26.53556 -2.63466  -23.24809 1.000 78.48513  ? 101 ASP E OD2 1 
ATOM   3676 N N   . TYR C 3 51  ? 24.34772 2.80427   -24.06617 1.000 107.72974 ? 102 TYR E N   1 
ATOM   3677 C CA  . TYR C 3 51  ? 23.14877 3.59199   -24.33806 1.000 115.00202 ? 102 TYR E CA  1 
ATOM   3678 C C   . TYR C 3 51  ? 22.91673 3.74852   -25.83639 1.000 118.57014 ? 102 TYR E C   1 
ATOM   3679 O O   . TYR C 3 51  ? 21.79155 3.58460   -26.32275 1.000 113.15265 ? 102 TYR E O   1 
ATOM   3680 C CB  . TYR C 3 51  ? 23.25487 4.95994   -23.66383 1.000 107.27381 ? 102 TYR E CB  1 
ATOM   3681 C CG  . TYR C 3 51  ? 21.96705 5.75001   -23.69771 1.000 104.19219 ? 102 TYR E CG  1 
ATOM   3682 C CD1 . TYR C 3 51  ? 20.77498 5.18912   -23.25957 1.000 104.73299 ? 102 TYR E CD1 1 
ATOM   3683 C CD2 . TYR C 3 51  ? 21.94201 7.05479   -24.17180 1.000 107.36464 ? 102 TYR E CD2 1 
ATOM   3684 C CE1 . TYR C 3 51  ? 19.59415 5.90548   -23.29168 1.000 107.95033 ? 102 TYR E CE1 1 
ATOM   3685 C CE2 . TYR C 3 51  ? 20.76582 7.77981   -24.20664 1.000 121.67009 ? 102 TYR E CE2 1 
ATOM   3686 C CZ  . TYR C 3 51  ? 19.59507 7.20015   -23.76500 1.000 124.65631 ? 102 TYR E CZ  1 
ATOM   3687 O OH  . TYR C 3 51  ? 18.42100 7.91710   -23.79740 1.000 132.53141 ? 102 TYR E OH  1 
ATOM   3688 N N   . GLU C 3 52  ? 23.97331 4.07215   -26.58610 1.000 123.08148 ? 103 GLU E N   1 
ATOM   3689 C CA  . GLU C 3 52  ? 23.83263 4.22017   -28.03141 1.000 127.56205 ? 103 GLU E CA  1 
ATOM   3690 C C   . GLU C 3 52  ? 23.49379 2.89076   -28.69357 1.000 122.92267 ? 103 GLU E C   1 
ATOM   3691 O O   . GLU C 3 52  ? 22.68548 2.84538   -29.62847 1.000 129.13433 ? 103 GLU E O   1 
ATOM   3692 C CB  . GLU C 3 52  ? 25.10925 4.81252   -28.62747 1.000 142.29748 ? 103 GLU E CB  1 
ATOM   3693 C CG  . GLU C 3 52  ? 25.37243 6.25406   -28.21766 1.000 154.36452 ? 103 GLU E CG  1 
ATOM   3694 C CD  . GLU C 3 52  ? 24.30828 7.21135   -28.72333 1.000 155.15769 ? 103 GLU E CD  1 
ATOM   3695 O OE1 . GLU C 3 52  ? 23.70764 6.93344   -29.78312 1.000 156.99272 ? 103 GLU E OE1 1 
ATOM   3696 O OE2 . GLU C 3 52  ? 24.07208 8.24302   -28.05973 1.000 144.86716 ? 103 GLU E OE2 1 
ATOM   3697 N N   . GLU C 3 53  ? 24.10767 1.79969   -28.22889 1.000 115.07983 ? 104 GLU E N   1 
ATOM   3698 C CA  . GLU C 3 53  ? 23.77522 0.48253   -28.76217 1.000 113.74375 ? 104 GLU E CA  1 
ATOM   3699 C C   . GLU C 3 53  ? 22.32353 0.12431   -28.47219 1.000 110.39598 ? 104 GLU E C   1 
ATOM   3700 O O   . GLU C 3 53  ? 21.62317 -0.41003  -29.33985 1.000 110.78863 ? 104 GLU E O   1 
ATOM   3701 C CB  . GLU C 3 53  ? 24.71613 -0.57660  -28.18507 1.000 106.68059 ? 104 GLU E CB  1 
ATOM   3702 C CG  . GLU C 3 53  ? 26.09972 -0.61365  -28.82376 1.000 119.10354 ? 104 GLU E CG  1 
ATOM   3703 C CD  . GLU C 3 53  ? 26.89120 0.66016   -28.59669 1.000 145.14407 ? 104 GLU E CD  1 
ATOM   3704 O OE1 . GLU C 3 53  ? 26.83852 1.20365   -27.47301 1.000 123.26725 ? 104 GLU E OE1 1 
ATOM   3705 O OE2 . GLU C 3 53  ? 27.56528 1.11861   -29.54329 1.000 155.47211 ? 104 GLU E OE2 1 
ATOM   3706 N N   . LEU C 3 54  ? 21.85298 0.41408   -27.25610 1.000 109.14169 ? 105 LEU E N   1 
ATOM   3707 C CA  . LEU C 3 54  ? 20.45660 0.15271   -26.92183 1.000 107.40757 ? 105 LEU E CA  1 
ATOM   3708 C C   . LEU C 3 54  ? 19.51984 0.99778   -27.77519 1.000 110.70983 ? 105 LEU E C   1 
ATOM   3709 O O   . LEU C 3 54  ? 18.45446 0.52821   -28.19165 1.000 112.72376 ? 105 LEU E O   1 
ATOM   3710 C CB  . LEU C 3 54  ? 20.21137 0.41395   -25.43577 1.000 102.79875 ? 105 LEU E CB  1 
ATOM   3711 C CG  . LEU C 3 54  ? 18.77859 0.18176   -24.94853 1.000 107.82790 ? 105 LEU E CG  1 
ATOM   3712 C CD1 . LEU C 3 54  ? 18.41890 -1.29494  -25.01941 1.000 93.11403  ? 105 LEU E CD1 1 
ATOM   3713 C CD2 . LEU C 3 54  ? 18.58585 0.71797   -23.53898 1.000 100.40992 ? 105 LEU E CD2 1 
ATOM   3714 N N   . ARG C 3 55  ? 19.89776 2.25136   -28.03914 1.000 105.62549 ? 106 ARG E N   1 
ATOM   3715 C CA  . ARG C 3 55  ? 19.07768 3.11144   -28.88619 1.000 112.39633 ? 106 ARG E CA  1 
ATOM   3716 C C   . ARG C 3 55  ? 18.94354 2.53502   -30.29028 1.000 119.93675 ? 106 ARG E C   1 
ATOM   3717 O O   . ARG C 3 55  ? 17.85033 2.53667   -30.86890 1.000 122.19216 ? 106 ARG E O   1 
ATOM   3718 C CB  . ARG C 3 55  ? 19.67601 4.51844   -28.93486 1.000 117.85179 ? 106 ARG E CB  1 
ATOM   3719 C CG  . ARG C 3 55  ? 19.40509 5.27203   -30.22873 1.000 132.98755 ? 106 ARG E CG  1 
ATOM   3720 C CD  . ARG C 3 55  ? 20.17540 6.58146   -30.28392 1.000 138.54523 ? 106 ARG E CD  1 
ATOM   3721 N NE  . ARG C 3 55  ? 19.51282 7.63907   -29.53004 1.000 154.29417 ? 106 ARG E NE  1 
ATOM   3722 C CZ  . ARG C 3 55  ? 19.87295 8.03361   -28.31642 1.000 147.10968 ? 106 ARG E CZ  1 
ATOM   3723 N NH1 . ARG C 3 55  ? 20.89311 7.47806   -27.68339 1.000 135.00059 ? 106 ARG E NH1 1 
ATOM   3724 N NH2 . ARG C 3 55  ? 19.19231 9.01024   -27.72302 1.000 143.14292 ? 106 ARG E NH2 1 
ATOM   3725 N N   . GLU C 3 56  ? 20.04587 2.03300   -30.85289 1.000 119.13384 ? 107 GLU E N   1 
ATOM   3726 C CA  . GLU C 3 56  ? 19.99651 1.45094   -32.19026 1.000 113.84921 ? 107 GLU E CA  1 
ATOM   3727 C C   . GLU C 3 56  ? 19.13355 0.19527   -32.21938 1.000 115.33911 ? 107 GLU E C   1 
ATOM   3728 O O   . GLU C 3 56  ? 18.32411 0.01436   -33.13648 1.000 130.41817 ? 107 GLU E O   1 
ATOM   3729 C CB  . GLU C 3 56  ? 21.41296 1.14266   -32.68168 1.000 111.80341 ? 107 GLU E CB  1 
ATOM   3730 C CG  . GLU C 3 56  ? 22.29407 2.36927   -32.94385 1.000 118.20492 ? 107 GLU E CG  1 
ATOM   3731 C CD  . GLU C 3 56  ? 21.79829 3.27380   -34.07014 1.000 140.84999 ? 107 GLU E CD  1 
ATOM   3732 O OE1 . GLU C 3 56  ? 20.71649 3.02291   -34.64280 1.000 134.31654 ? 107 GLU E OE1 1 
ATOM   3733 O OE2 . GLU C 3 56  ? 22.50466 4.25545   -34.38380 1.000 149.79917 ? 107 GLU E OE2 1 
ATOM   3734 N N   . GLN C 3 57  ? 19.29274 -0.68455  -31.22738 1.000 97.80999  ? 108 GLN E N   1 
ATOM   3735 C CA  . GLN C 3 57  ? 18.48511 -1.89990  -31.18312 1.000 102.04481 ? 108 GLN E CA  1 
ATOM   3736 C C   . GLN C 3 57  ? 17.01500 -1.58180  -30.93929 1.000 93.56030  ? 108 GLN E C   1 
ATOM   3737 O O   . GLN C 3 57  ? 16.13214 -2.19333  -31.55206 1.000 102.49926 ? 108 GLN E O   1 
ATOM   3738 C CB  . GLN C 3 57  ? 19.01461 -2.84693  -30.10615 1.000 91.53959  ? 108 GLN E CB  1 
ATOM   3739 C CG  . GLN C 3 57  ? 20.47949 -3.21978  -30.26801 1.000 101.49390 ? 108 GLN E CG  1 
ATOM   3740 C CD  . GLN C 3 57  ? 20.73696 -4.05283  -31.50770 1.000 127.24313 ? 108 GLN E CD  1 
ATOM   3741 O OE1 . GLN C 3 57  ? 19.88409 -4.83124  -31.93476 1.000 128.18407 ? 108 GLN E OE1 1 
ATOM   3742 N NE2 . GLN C 3 57  ? 21.91841 -3.89340  -32.09306 1.000 131.18657 ? 108 GLN E NE2 1 
ATOM   3743 N N   . LEU C 3 58  ? 16.73141 -0.63016  -30.04735 1.000 102.56695 ? 109 LEU E N   1 
ATOM   3744 C CA  . LEU C 3 58  ? 15.34846 -0.27399  -29.75496 1.000 116.95488 ? 109 LEU E CA  1 
ATOM   3745 C C   . LEU C 3 58  ? 14.67319 0.43250   -30.92243 1.000 118.02854 ? 109 LEU E C   1 
ATOM   3746 O O   . LEU C 3 58  ? 13.44001 0.43508   -30.99813 1.000 123.81928 ? 109 LEU E O   1 
ATOM   3747 C CB  . LEU C 3 58  ? 15.28447 0.60364   -28.50402 1.000 118.97081 ? 109 LEU E CB  1 
ATOM   3748 C CG  . LEU C 3 58  ? 15.04266 -0.12284  -27.17878 1.000 101.58201 ? 109 LEU E CG  1 
ATOM   3749 C CD1 . LEU C 3 58  ? 14.80658 0.87394   -26.05612 1.000 123.31966 ? 109 LEU E CD1 1 
ATOM   3750 C CD2 . LEU C 3 58  ? 13.87312 -1.08936  -27.29507 1.000 100.77532 ? 109 LEU E CD2 1 
ATOM   3751 N N   . SER C 3 59  ? 15.44543 1.03355   -31.82368 1.000 126.50612 ? 110 SER E N   1 
ATOM   3752 C CA  . SER C 3 59  ? 14.86570 1.68115   -32.99132 1.000 134.07725 ? 110 SER E CA  1 
ATOM   3753 C C   . SER C 3 59  ? 14.28025 0.64337   -33.94079 1.000 137.10093 ? 110 SER E C   1 
ATOM   3754 O O   . SER C 3 59  ? 14.87345 -0.41427  -34.17281 1.000 137.87522 ? 110 SER E O   1 
ATOM   3755 C CB  . SER C 3 59  ? 15.91968 2.51957   -33.71418 1.000 125.70484 ? 110 SER E CB  1 
ATOM   3756 O OG  . SER C 3 59  ? 16.37093 3.58755   -32.89954 1.000 146.73166 ? 110 SER E OG  1 
ATOM   3757 N N   . SER C 3 60  ? 13.10538 0.95685   -34.49001 1.000 143.60796 ? 111 SER E N   1 
ATOM   3758 C CA  . SER C 3 60  ? 12.40440 0.09150   -35.43922 1.000 155.75690 ? 111 SER E CA  1 
ATOM   3759 C C   . SER C 3 60  ? 12.13317 -1.28789  -34.83248 1.000 141.31285 ? 111 SER E C   1 
ATOM   3760 O O   . SER C 3 60  ? 12.63346 -2.31572  -35.29432 1.000 144.40530 ? 111 SER E O   1 
ATOM   3761 C CB  . SER C 3 60  ? 13.18257 -0.02248  -36.75533 1.000 160.28962 ? 111 SER E CB  1 
ATOM   3762 O OG  . SER C 3 60  ? 13.33389 1.24566   -37.36955 1.000 144.66991 ? 111 SER E OG  1 
ATOM   3763 N N   . VAL C 3 61  ? 11.32619 -1.28901  -33.77517 1.000 134.06459 ? 112 VAL E N   1 
ATOM   3764 C CA  . VAL C 3 61  ? 10.89476 -2.50986  -33.10353 1.000 136.32317 ? 112 VAL E CA  1 
ATOM   3765 C C   . VAL C 3 61  ? 9.40914  -2.69057  -33.38615 1.000 133.93208 ? 112 VAL E C   1 
ATOM   3766 O O   . VAL C 3 61  ? 8.59176  -1.83215  -33.02987 1.000 131.46260 ? 112 VAL E O   1 
ATOM   3767 C CB  . VAL C 3 61  ? 11.17879 -2.45788  -31.59457 1.000 134.93861 ? 112 VAL E CB  1 
ATOM   3768 C CG1 . VAL C 3 61  ? 10.32136 -3.46795  -30.85505 1.000 131.44753 ? 112 VAL E CG1 1 
ATOM   3769 C CG2 . VAL C 3 61  ? 12.65494 -2.71200  -31.32690 1.000 120.07925 ? 112 VAL E CG2 1 
ATOM   3770 N N   . SER C 3 62  ? 9.06164  -3.80565  -34.03283 1.000 126.00348 ? 113 SER E N   1 
ATOM   3771 C CA  . SER C 3 62  ? 7.69239  -3.99937  -34.50157 1.000 133.31755 ? 113 SER E CA  1 
ATOM   3772 C C   . SER C 3 62  ? 6.73684  -4.28201  -33.34748 1.000 145.42823 ? 113 SER E C   1 
ATOM   3773 O O   . SER C 3 62  ? 5.64320  -3.70896  -33.28097 1.000 148.12334 ? 113 SER E O   1 
ATOM   3774 C CB  . SER C 3 62  ? 7.64852  -5.13301  -35.52672 1.000 139.82961 ? 113 SER E CB  1 
ATOM   3775 O OG  . SER C 3 62  ? 8.00784  -6.36956  -34.93545 1.000 141.50655 ? 113 SER E OG  1 
ATOM   3776 N N   . SER C 3 63  ? 7.12749  -5.16292  -32.43049 1.000 146.68330 ? 114 SER E N   1 
ATOM   3777 C CA  . SER C 3 63  ? 6.26833  -5.58776  -31.33436 1.000 144.17496 ? 114 SER E CA  1 
ATOM   3778 C C   . SER C 3 63  ? 6.95166  -5.31620  -30.00219 1.000 141.78448 ? 114 SER E C   1 
ATOM   3779 O O   . SER C 3 63  ? 8.15396  -5.55128  -29.85130 1.000 141.53885 ? 114 SER E O   1 
ATOM   3780 C CB  . SER C 3 63  ? 5.91960  -7.07522  -31.45277 1.000 129.41117 ? 114 SER E CB  1 
ATOM   3781 O OG  . SER C 3 63  ? 6.92886  -7.88209  -30.87407 1.000 124.55557 ? 114 SER E OG  1 
ATOM   3782 N N   . PHE C 3 64  ? 6.17658  -4.82844  -29.03522 1.000 137.55769 ? 115 PHE E N   1 
ATOM   3783 C CA  . PHE C 3 64  ? 6.70325  -4.45114  -27.72836 1.000 131.86953 ? 115 PHE E CA  1 
ATOM   3784 C C   . PHE C 3 64  ? 5.66781  -4.79067  -26.66876 1.000 128.55195 ? 115 PHE E C   1 
ATOM   3785 O O   . PHE C 3 64  ? 4.55786  -4.25095  -26.68957 1.000 141.33685 ? 115 PHE E O   1 
ATOM   3786 C CB  . PHE C 3 64  ? 7.04722  -2.95927  -27.69085 1.000 130.61675 ? 115 PHE E CB  1 
ATOM   3787 C CG  . PHE C 3 64  ? 8.22703  -2.62553  -26.82731 1.000 124.59545 ? 115 PHE E CG  1 
ATOM   3788 C CD1 . PHE C 3 64  ? 9.51458  -2.90033  -27.25588 1.000 125.42472 ? 115 PHE E CD1 1 
ATOM   3789 C CD2 . PHE C 3 64  ? 8.05092  -2.01458  -25.59779 1.000 128.36719 ? 115 PHE E CD2 1 
ATOM   3790 C CE1 . PHE C 3 64  ? 10.60439 -2.58610  -26.46773 1.000 119.19842 ? 115 PHE E CE1 1 
ATOM   3791 C CE2 . PHE C 3 64  ? 9.13644  -1.69671  -24.80576 1.000 136.09403 ? 115 PHE E CE2 1 
ATOM   3792 C CZ  . PHE C 3 64  ? 10.41499 -1.98277  -25.24135 1.000 130.65029 ? 115 PHE E CZ  1 
ATOM   3793 N N   . GLU C 3 65  ? 6.02864  -5.68124  -25.74792 1.000 111.79535 ? 116 GLU E N   1 
ATOM   3794 C CA  . GLU C 3 65  ? 5.14779  -6.09475  -24.66409 1.000 100.33510 ? 116 GLU E CA  1 
ATOM   3795 C C   . GLU C 3 65  ? 5.86780  -5.91051  -23.33829 1.000 114.50387 ? 116 GLU E C   1 
ATOM   3796 O O   . GLU C 3 65  ? 7.02130  -6.32640  -23.19346 1.000 117.36486 ? 116 GLU E O   1 
ATOM   3797 C CB  . GLU C 3 65  ? 4.71138  -7.55450  -24.82594 1.000 111.26787 ? 116 GLU E CB  1 
ATOM   3798 C CG  . GLU C 3 65  ? 3.77379  -8.04220  -23.73283 1.000 118.96170 ? 116 GLU E CG  1 
ATOM   3799 C CD  . GLU C 3 65  ? 3.66138  -9.55353  -23.69093 1.000 133.33290 ? 116 GLU E CD  1 
ATOM   3800 O OE1 . GLU C 3 65  ? 4.31950  -10.22342 -24.51453 1.000 135.16156 ? 116 GLU E OE1 1 
ATOM   3801 O OE2 . GLU C 3 65  ? 2.91725  -10.07179 -22.83207 1.000 136.93131 ? 116 GLU E OE2 1 
ATOM   3802 N N   . ARG C 3 66  ? 5.18763  -5.29527  -22.37539 1.000 115.05033 ? 117 ARG E N   1 
ATOM   3803 C CA  . ARG C 3 66  ? 5.72767  -5.09457  -21.03724 1.000 102.21102 ? 117 ARG E CA  1 
ATOM   3804 C C   . ARG C 3 66  ? 5.16838  -6.17081  -20.11523 1.000 97.98715  ? 117 ARG E C   1 
ATOM   3805 O O   . ARG C 3 66  ? 3.94732  -6.30289  -19.97834 1.000 100.65102 ? 117 ARG E O   1 
ATOM   3806 C CB  . ARG C 3 66  ? 5.38428  -3.70132  -20.51114 1.000 109.90153 ? 117 ARG E CB  1 
ATOM   3807 C CG  . ARG C 3 66  ? 6.02535  -3.37082  -19.17331 1.000 109.79972 ? 117 ARG E CG  1 
ATOM   3808 C CD  . ARG C 3 66  ? 5.84584  -1.90363  -18.82026 1.000 108.27432 ? 117 ARG E CD  1 
ATOM   3809 N NE  . ARG C 3 66  ? 6.25620  -1.61922  -17.45044 1.000 113.00040 ? 117 ARG E NE  1 
ATOM   3810 C CZ  . ARG C 3 66  ? 5.43212  -1.59050  -16.41206 1.000 107.68121 ? 117 ARG E CZ  1 
ATOM   3811 N NH1 . ARG C 3 66  ? 4.13747  -1.82496  -16.55044 1.000 112.58983 ? 117 ARG E NH1 1 
ATOM   3812 N NH2 . ARG C 3 66  ? 5.91934  -1.32065  -15.20428 1.000 106.11472 ? 117 ARG E NH2 1 
ATOM   3813 N N   . PHE C 3 67  ? 6.05955  -6.93583  -19.48847 1.000 99.06080  ? 118 PHE E N   1 
ATOM   3814 C CA  . PHE C 3 67  ? 5.66259  -8.02045  -18.60380 1.000 98.83883  ? 118 PHE E CA  1 
ATOM   3815 C C   . PHE C 3 67  ? 6.54102  -8.00746  -17.36095 1.000 98.63371  ? 118 PHE E C   1 
ATOM   3816 O O   . PHE C 3 67  ? 7.66838  -7.50691  -17.37488 1.000 97.38716  ? 118 PHE E O   1 
ATOM   3817 C CB  . PHE C 3 67  ? 5.74408  -9.38275  -19.30964 1.000 97.64769  ? 118 PHE E CB  1 
ATOM   3818 C CG  . PHE C 3 67  ? 7.14598  -9.82046  -19.63103 1.000 107.55245 ? 118 PHE E CG  1 
ATOM   3819 C CD1 . PHE C 3 67  ? 7.79680  -9.33602  -20.75449 1.000 101.38551 ? 118 PHE E CD1 1 
ATOM   3820 C CD2 . PHE C 3 67  ? 7.80813  -10.72607 -18.81787 1.000 87.94962  ? 118 PHE E CD2 1 
ATOM   3821 C CE1 . PHE C 3 67  ? 9.08436  -9.73832  -21.05509 1.000 88.30967  ? 118 PHE E CE1 1 
ATOM   3822 C CE2 . PHE C 3 67  ? 9.09544  -11.13220 -19.11358 1.000 89.28627  ? 118 PHE E CE2 1 
ATOM   3823 C CZ  . PHE C 3 67  ? 9.73352  -10.63844 -20.23399 1.000 88.00430  ? 118 PHE E CZ  1 
ATOM   3824 N N   . GLU C 3 68  ? 6.00491  -8.56794  -16.27904 1.000 100.07345 ? 119 GLU E N   1 
ATOM   3825 C CA  . GLU C 3 68  ? 6.70366  -8.62123  -14.99622 1.000 91.97979  ? 119 GLU E CA  1 
ATOM   3826 C C   . GLU C 3 68  ? 7.62116  -9.83665  -14.98873 1.000 87.77299  ? 119 GLU E C   1 
ATOM   3827 O O   . GLU C 3 68  ? 7.18021  -10.96248 -14.74569 1.000 76.19022  ? 119 GLU E O   1 
ATOM   3828 C CB  . GLU C 3 68  ? 5.70617  -8.67652  -13.84526 1.000 94.82921  ? 119 GLU E CB  1 
ATOM   3829 C CG  . GLU C 3 68  ? 6.15154  -7.92925  -12.60001 1.000 108.93759 ? 119 GLU E CG  1 
ATOM   3830 C CD  . GLU C 3 68  ? 5.04683  -7.80576  -11.56961 1.000 112.27063 ? 119 GLU E CD  1 
ATOM   3831 O OE1 . GLU C 3 68  ? 3.90109  -8.19852  -11.87520 1.000 117.04744 ? 119 GLU E OE1 1 
ATOM   3832 O OE2 . GLU C 3 68  ? 5.32411  -7.31608  -10.45436 1.000 109.36743 ? 119 GLU E OE2 1 
ATOM   3833 N N   . ILE C 3 69  ? 8.90978  -9.60846  -15.25339 1.000 90.17642  ? 120 ILE E N   1 
ATOM   3834 C CA  . ILE C 3 69  ? 9.87179  -10.70744 -15.27056 1.000 90.54932  ? 120 ILE E CA  1 
ATOM   3835 C C   . ILE C 3 69  ? 9.99975  -11.32647 -13.88327 1.000 89.75646  ? 120 ILE E C   1 
ATOM   3836 O O   . ILE C 3 69  ? 10.05785 -12.55364 -13.73649 1.000 93.49823  ? 120 ILE E O   1 
ATOM   3837 C CB  . ILE C 3 69  ? 11.22981 -10.22060 -15.81465 1.000 80.72355  ? 120 ILE E CB  1 
ATOM   3838 C CG1 . ILE C 3 69  ? 12.28108 -11.32850 -15.72228 1.000 67.93792  ? 120 ILE E CG1 1 
ATOM   3839 C CG2 . ILE C 3 69  ? 11.69113 -8.95830  -15.09091 1.000 76.38001  ? 120 ILE E CG2 1 
ATOM   3840 C CD1 . ILE C 3 69  ? 13.61729 -10.95255 -16.32606 1.000 62.62997  ? 120 ILE E CD1 1 
ATOM   3841 N N   . PHE C 3 70  ? 10.03639 -10.49512 -12.84862 1.000 87.94693  ? 121 PHE E N   1 
ATOM   3842 C CA  . PHE C 3 70  ? 10.10875 -10.96020 -11.46492 1.000 87.99251  ? 121 PHE E CA  1 
ATOM   3843 C C   . PHE C 3 70  ? 8.98414  -10.31800 -10.66564 1.000 100.13399 ? 121 PHE E C   1 
ATOM   3844 O O   . PHE C 3 70  ? 9.00932  -9.08830  -10.45119 1.000 99.61572  ? 121 PHE E O   1 
ATOM   3845 C CB  . PHE C 3 70  ? 11.46379 -10.63111 -10.84487 1.000 86.86540  ? 121 PHE E CB  1 
ATOM   3846 C CG  . PHE C 3 70  ? 12.62431 -11.29099 -11.53092 1.000 62.11401  ? 121 PHE E CG  1 
ATOM   3847 C CD1 . PHE C 3 70  ? 12.64546 -12.66171 -11.72176 1.000 62.63983  ? 121 PHE E CD1 1 
ATOM   3848 C CD2 . PHE C 3 70  ? 13.70013 -10.54029 -11.97504 1.000 67.49338  ? 121 PHE E CD2 1 
ATOM   3849 C CE1 . PHE C 3 70  ? 13.71518 -13.27141 -12.34873 1.000 76.36607  ? 121 PHE E CE1 1 
ATOM   3850 C CE2 . PHE C 3 70  ? 14.77296 -11.14335 -12.60215 1.000 64.92723  ? 121 PHE E CE2 1 
ATOM   3851 C CZ  . PHE C 3 70  ? 14.78045 -12.51079 -12.78954 1.000 79.04033  ? 121 PHE E CZ  1 
ATOM   3852 N N   . PRO C 3 71  ? 7.98697  -11.08460 -10.22349 1.000 103.38156 ? 122 PRO E N   1 
ATOM   3853 C CA  . PRO C 3 71  ? 6.94754  -10.51028 -9.36060  1.000 103.86618 ? 122 PRO E CA  1 
ATOM   3854 C C   . PRO C 3 71  ? 7.54950  -9.95367  -8.07897  1.000 108.97837 ? 122 PRO E C   1 
ATOM   3855 O O   . PRO C 3 71  ? 8.48902  -10.51810 -7.51572  1.000 104.68281 ? 122 PRO E O   1 
ATOM   3856 C CB  . PRO C 3 71  ? 6.01984  -11.69898 -9.08260  1.000 119.92194 ? 122 PRO E CB  1 
ATOM   3857 C CG  . PRO C 3 71  ? 6.26762  -12.64439 -10.21709 1.000 116.36937 ? 122 PRO E CG  1 
ATOM   3858 C CD  . PRO C 3 71  ? 7.72354  -12.49762 -10.54107 1.000 119.20227 ? 122 PRO E CD  1 
ATOM   3859 N N   . LYS C 3 72  ? 6.99650  -8.82817  -7.62285  1.000 117.21851 ? 123 LYS E N   1 
ATOM   3860 C CA  . LYS C 3 72  ? 7.57194  -8.12764  -6.47831  1.000 122.17934 ? 123 LYS E CA  1 
ATOM   3861 C C   . LYS C 3 72  ? 7.47663  -8.96306  -5.20619  1.000 122.28469 ? 123 LYS E C   1 
ATOM   3862 O O   . LYS C 3 72  ? 8.46491  -9.12239  -4.47991  1.000 113.81551 ? 123 LYS E O   1 
ATOM   3863 C CB  . LYS C 3 72  ? 6.87622  -6.77881  -6.29280  1.000 113.77243 ? 123 LYS E CB  1 
ATOM   3864 C CG  . LYS C 3 72  ? 7.51562  -5.88536  -5.24484  1.000 104.25290 ? 123 LYS E CG  1 
ATOM   3865 C CD  . LYS C 3 72  ? 6.70522  -4.61663  -5.03525  1.000 106.02518 ? 123 LYS E CD  1 
ATOM   3866 C CE  . LYS C 3 72  ? 7.56327  -3.50324  -4.45720  1.000 99.13236  ? 123 LYS E CE  1 
ATOM   3867 N NZ  . LYS C 3 72  ? 6.78262  -2.25424  -4.24084  1.000 106.17847 ? 123 LYS E NZ  1 
ATOM   3868 N N   . GLU C 3 73  ? 6.29164  -9.50152  -4.91724  1.000 115.60992 ? 124 GLU E N   1 
ATOM   3869 C CA  . GLU C 3 73  ? 6.09934  -10.25982 -3.68590  1.000 114.85594 ? 124 GLU E CA  1 
ATOM   3870 C C   . GLU C 3 73  ? 6.72067  -11.65044 -3.76661  1.000 125.18409 ? 124 GLU E C   1 
ATOM   3871 O O   . GLU C 3 73  ? 7.33748  -12.11376 -2.80063  1.000 122.00215 ? 124 GLU E O   1 
ATOM   3872 C CB  . GLU C 3 73  ? 4.60647  -10.36749 -3.35889  1.000 106.55035 ? 124 GLU E CB  1 
ATOM   3873 C CG  . GLU C 3 73  ? 3.89214  -9.03596  -3.10881  1.000 124.59974 ? 124 GLU E CG  1 
ATOM   3874 C CD  . GLU C 3 73  ? 3.65410  -8.22401  -4.37274  1.000 129.84843 ? 124 GLU E CD  1 
ATOM   3875 O OE1 . GLU C 3 73  ? 3.99569  -8.70712  -5.47306  1.000 139.96462 ? 124 GLU E OE1 1 
ATOM   3876 O OE2 . GLU C 3 73  ? 3.12319  -7.09809  -4.26439  1.000 127.72592 ? 124 GLU E OE2 1 
ATOM   3877 N N   . SER C 3 74  ? 6.56808  -12.32831 -4.90612  1.000 124.22300 ? 125 SER E N   1 
ATOM   3878 C CA  . SER C 3 74  ? 6.92484  -13.74118 -4.99286  1.000 111.92800 ? 125 SER E CA  1 
ATOM   3879 C C   . SER C 3 74  ? 8.42966  -13.96220 -5.11239  1.000 112.56129 ? 125 SER E C   1 
ATOM   3880 O O   . SER C 3 74  ? 8.95896  -14.92967 -4.55386  1.000 101.98766 ? 125 SER E O   1 
ATOM   3881 C CB  . SER C 3 74  ? 6.20331  -14.38657 -6.17646  1.000 114.42980 ? 125 SER E CB  1 
ATOM   3882 O OG  . SER C 3 74  ? 6.61167  -15.73263 -6.35021  1.000 141.74292 ? 125 SER E OG  1 
ATOM   3883 N N   . SER C 3 75  ? 9.13314  -13.08788 -5.83538  1.000 103.51615 ? 126 SER E N   1 
ATOM   3884 C CA  . SER C 3 75  ? 10.50913 -13.38876 -6.22441  1.000 102.89727 ? 126 SER E CA  1 
ATOM   3885 C C   . SER C 3 75  ? 11.45246 -13.39210 -5.02611  1.000 102.52420 ? 126 SER E C   1 
ATOM   3886 O O   . SER C 3 75  ? 12.26333 -14.31223 -4.86844  1.000 103.60633 ? 126 SER E O   1 
ATOM   3887 C CB  . SER C 3 75  ? 10.98586 -12.39294 -7.28059  1.000 99.40330  ? 126 SER E CB  1 
ATOM   3888 O OG  . SER C 3 75  ? 10.22236 -12.51146 -8.46747  1.000 94.11723  ? 126 SER E OG  1 
ATOM   3889 N N   . TRP C 3 76  ? 11.36842 -12.37555 -4.17233  1.000 108.67043 ? 127 TRP E N   1 
ATOM   3890 C CA  . TRP C 3 76  ? 12.30835 -12.21790 -3.06098  1.000 118.79166 ? 127 TRP E CA  1 
ATOM   3891 C C   . TRP C 3 76  ? 11.57982 -12.34431 -1.73133  1.000 111.68769 ? 127 TRP E C   1 
ATOM   3892 O O   . TRP C 3 76  ? 10.97213 -11.36826 -1.25580  1.000 115.16641 ? 127 TRP E O   1 
ATOM   3893 C CB  . TRP C 3 76  ? 13.02918 -10.87479 -3.15618  1.000 105.62658 ? 127 TRP E CB  1 
ATOM   3894 C CG  . TRP C 3 76  ? 13.57440 -10.60369 -4.52391  1.000 102.11484 ? 127 TRP E CG  1 
ATOM   3895 C CD1 . TRP C 3 76  ? 14.80213 -10.95782 -5.00304  1.000 105.91581 ? 127 TRP E CD1 1 
ATOM   3896 C CD2 . TRP C 3 76  ? 12.90737 -9.92403  -5.59319  1.000 95.43758  ? 127 TRP E CD2 1 
ATOM   3897 N NE1 . TRP C 3 76  ? 14.94107 -10.54015 -6.30463  1.000 91.78620  ? 127 TRP E NE1 1 
ATOM   3898 C CE2 . TRP C 3 76  ? 13.79165 -9.90199  -6.69018  1.000 100.16385 ? 127 TRP E CE2 1 
ATOM   3899 C CE3 . TRP C 3 76  ? 11.64924 -9.32990  -5.72894  1.000 105.32909 ? 127 TRP E CE3 1 
ATOM   3900 C CZ2 . TRP C 3 76  ? 13.45731 -9.31048  -7.90642  1.000 102.64992 ? 127 TRP E CZ2 1 
ATOM   3901 C CZ3 . TRP C 3 76  ? 11.31893 -8.74496  -6.93824  1.000 120.07953 ? 127 TRP E CZ3 1 
ATOM   3902 C CH2 . TRP C 3 76  ? 12.22019 -8.73678  -8.00931  1.000 109.83175 ? 127 TRP E CH2 1 
ATOM   3903 N N   . PRO C 3 77  ? 11.60855 -13.51691 -1.09452  1.000 99.88375  ? 128 PRO E N   1 
ATOM   3904 C CA  . PRO C 3 77  ? 10.89013 -13.68878 0.17513   1.000 103.89527 ? 128 PRO E CA  1 
ATOM   3905 C C   . PRO C 3 77  ? 11.64128 -13.14012 1.37989   1.000 118.42171 ? 128 PRO E C   1 
ATOM   3906 O O   . PRO C 3 77  ? 11.02314 -12.63104 2.32041   1.000 116.08628 ? 128 PRO E O   1 
ATOM   3907 C CB  . PRO C 3 77  ? 10.72381 -15.20984 0.26828   1.000 107.82615 ? 128 PRO E CB  1 
ATOM   3908 C CG  . PRO C 3 77  ? 11.91854 -15.74395 -0.45239  1.000 101.94295 ? 128 PRO E CG  1 
ATOM   3909 C CD  . PRO C 3 77  ? 12.17849 -14.78414 -1.58591  1.000 91.11449  ? 128 PRO E CD  1 
ATOM   3910 N N   . ASN C 3 78  ? 12.97216 -13.23644 1.36654   1.000 106.33464 ? 129 ASN E N   1 
ATOM   3911 C CA  . ASN C 3 78  ? 13.79724 -12.87765 2.51423   1.000 94.18298  ? 129 ASN E CA  1 
ATOM   3912 C C   . ASN C 3 78  ? 14.48565 -11.52702 2.34320   1.000 93.09136  ? 129 ASN E C   1 
ATOM   3913 O O   . ASN C 3 78  ? 15.58017 -11.31523 2.87662   1.000 85.80955  ? 129 ASN E O   1 
ATOM   3914 C CB  . ASN C 3 78  ? 14.83030 -13.97141 2.78362   1.000 94.11371  ? 129 ASN E CB  1 
ATOM   3915 C CG  . ASN C 3 78  ? 14.19166 -15.31171 3.09215   1.000 93.04884  ? 129 ASN E CG  1 
ATOM   3916 O OD1 . ASN C 3 78  ? 13.05478 -15.37750 3.55988   1.000 91.70568  ? 129 ASN E OD1 1 
ATOM   3917 N ND2 . ASN C 3 78  ? 14.92245 -16.38967 2.83230   1.000 81.97483  ? 129 ASN E ND2 1 
ATOM   3918 N N   . HIS C 3 79  ? 13.86516 -10.60841 1.60775   1.000 90.67759  ? 130 HIS E N   1 
ATOM   3919 C CA  . HIS C 3 79  ? 14.37628 -9.25519  1.45615   1.000 71.88490  ? 130 HIS E CA  1 
ATOM   3920 C C   . HIS C 3 79  ? 13.20574 -8.28561  1.48891   1.000 81.28171  ? 130 HIS E C   1 
ATOM   3921 O O   . HIS C 3 79  ? 12.06289 -8.65129  1.20322   1.000 100.85648 ? 130 HIS E O   1 
ATOM   3922 C CB  . HIS C 3 79  ? 15.17310 -9.08472  0.15532   1.000 88.12032  ? 130 HIS E CB  1 
ATOM   3923 C CG  . HIS C 3 79  ? 16.28111 -10.07699 -0.00956  1.000 78.93644  ? 130 HIS E CG  1 
ATOM   3924 N ND1 . HIS C 3 79  ? 16.07948 -11.33840 -0.52698  1.000 84.56503  ? 130 HIS E ND1 1 
ATOM   3925 C CD2 . HIS C 3 79  ? 17.60256 -9.99302  0.27335   1.000 72.20477  ? 130 HIS E CD2 1 
ATOM   3926 C CE1 . HIS C 3 79  ? 17.22872 -11.98931 -0.55451  1.000 89.87245  ? 130 HIS E CE1 1 
ATOM   3927 N NE2 . HIS C 3 79  ? 18.16884 -11.19528 -0.07441  1.000 83.67775  ? 130 HIS E NE2 1 
ATOM   3928 N N   . THR C 3 80  ? 13.50023 -7.03899  1.84404   1.000 75.61003  ? 131 THR E N   1 
ATOM   3929 C CA  . THR C 3 80  ? 12.47664 -6.00643  1.92814   1.000 89.40412  ? 131 THR E CA  1 
ATOM   3930 C C   . THR C 3 80  ? 12.44192 -5.23403  0.61546   1.000 89.71562  ? 131 THR E C   1 
ATOM   3931 O O   . THR C 3 80  ? 13.45434 -4.66182  0.19665   1.000 84.97389  ? 131 THR E O   1 
ATOM   3932 C CB  . THR C 3 80  ? 12.73736 -5.06199  3.09979   1.000 77.19558  ? 131 THR E CB  1 
ATOM   3933 O OG1 . THR C 3 80  ? 13.02074 -5.82591  4.27762   1.000 73.80232  ? 131 THR E OG1 1 
ATOM   3934 C CG2 . THR C 3 80  ? 11.50742 -4.21180  3.35770   1.000 83.49248  ? 131 THR E CG2 1 
ATOM   3935 N N   . VAL C 3 81  ? 11.27757 -5.22134  -0.03033  1.000 92.65219  ? 132 VAL E N   1 
ATOM   3936 C CA  . VAL C 3 81  ? 11.12469 -4.55170  -1.31526  1.000 82.99784  ? 132 VAL E CA  1 
ATOM   3937 C C   . VAL C 3 81  ? 10.45426 -3.18661  -1.19320  1.000 81.10300  ? 132 VAL E C   1 
ATOM   3938 O O   . VAL C 3 81  ? 10.58326 -2.36406  -2.11286  1.000 79.28833  ? 132 VAL E O   1 
ATOM   3939 C CB  . VAL C 3 81  ? 10.33769 -5.44187  -2.29886  1.000 86.11945  ? 132 VAL E CB  1 
ATOM   3940 C CG1 . VAL C 3 81  ? 11.07003 -6.75603  -2.52139  1.000 89.17636  ? 132 VAL E CG1 1 
ATOM   3941 C CG2 . VAL C 3 81  ? 8.93065  -5.69145  -1.77819  1.000 76.98597  ? 132 VAL E CG2 1 
ATOM   3942 N N   . THR C 3 82  ? 9.75207  -2.91837  -0.09225  1.000 96.08730  ? 133 THR E N   1 
ATOM   3943 C CA  . THR C 3 82  ? 9.04068  -1.65822  0.07687   1.000 97.98700  ? 133 THR E CA  1 
ATOM   3944 C C   . THR C 3 82  ? 9.93006  -0.52716  0.57654   1.000 94.99567  ? 133 THR E C   1 
ATOM   3945 O O   . THR C 3 82  ? 9.50441  0.63223   0.53874   1.000 88.97713  ? 133 THR E O   1 
ATOM   3946 C CB  . THR C 3 82  ? 7.86720  -1.84202  1.04365   1.000 98.26820  ? 133 THR E CB  1 
ATOM   3947 O OG1 . THR C 3 82  ? 8.35046  -2.34676  2.29515   1.000 88.49945  ? 133 THR E OG1 1 
ATOM   3948 C CG2 . THR C 3 82  ? 6.85091  -2.81754  0.46819   1.000 111.34361 ? 133 THR E CG2 1 
ATOM   3949 N N   . LYS C 3 83  a 11.14421 -0.82628  1.03855   1.000 100.85596 ? 133 LYS E N   1 
ATOM   3950 C CA  . LYS C 3 83  a 12.01913 0.20359   1.58373   1.000 96.37991  ? 133 LYS E CA  1 
ATOM   3951 C C   . LYS C 3 83  a 12.71807 1.02889   0.51187   1.000 98.90166  ? 133 LYS E C   1 
ATOM   3952 O O   . LYS C 3 83  a 13.27038 2.08622   0.83495   1.000 95.06683  ? 133 LYS E O   1 
ATOM   3953 C CB  . LYS C 3 83  a 13.07693 -0.42446  2.49548   1.000 85.38729  ? 133 LYS E CB  1 
ATOM   3954 C CG  . LYS C 3 83  a 12.55347 -0.89878  3.83899   1.000 94.71960  ? 133 LYS E CG  1 
ATOM   3955 C CD  . LYS C 3 83  a 11.74911 0.17244   4.55003   1.000 88.22685  ? 133 LYS E CD  1 
ATOM   3956 C CE  . LYS C 3 83  a 10.86645 -0.44234  5.62481   1.000 91.21569  ? 133 LYS E CE  1 
ATOM   3957 N NZ  . LYS C 3 83  a 9.60641  -0.99676  5.05926   1.000 106.49613 ? 133 LYS E NZ  1 
ATOM   3958 N N   . GLY C 3 84  ? 12.71100 0.58556   -0.74293  1.000 92.79333  ? 134 GLY E N   1 
ATOM   3959 C CA  . GLY C 3 84  ? 13.48876 1.26338   -1.76039  1.000 92.88569  ? 134 GLY E CA  1 
ATOM   3960 C C   . GLY C 3 84  ? 12.76907 2.39644   -2.46070  1.000 100.67053 ? 134 GLY E C   1 
ATOM   3961 O O   . GLY C 3 84  ? 12.03942 2.17883   -3.43245  1.000 103.48654 ? 134 GLY E O   1 
ATOM   3962 N N   . VAL C 3 85  ? 12.99326 3.62006   -1.97723  1.000 98.69906  ? 135 VAL E N   1 
ATOM   3963 C CA  . VAL C 3 85  ? 12.49619 4.83681   -2.60915  1.000 87.93493  ? 135 VAL E CA  1 
ATOM   3964 C C   . VAL C 3 85  ? 13.51210 5.93669   -2.34118  1.000 96.71442  ? 135 VAL E C   1 
ATOM   3965 O O   . VAL C 3 85  ? 14.35336 5.82792   -1.44678  1.000 104.09531 ? 135 VAL E O   1 
ATOM   3966 C CB  . VAL C 3 85  ? 11.09833 5.26136   -2.09393  1.000 79.27787  ? 135 VAL E CB  1 
ATOM   3967 C CG1 . VAL C 3 85  ? 9.99900  4.45410   -2.76953  1.000 86.77416  ? 135 VAL E CG1 1 
ATOM   3968 C CG2 . VAL C 3 85  ? 11.02307 5.11708   -0.58479  1.000 98.80995  ? 135 VAL E CG2 1 
ATOM   3969 N N   . THR C 3 86  ? 13.43193 7.00871   -3.12507  1.000 97.41561  ? 136 THR E N   1 
ATOM   3970 C CA  . THR C 3 86  ? 14.34093 8.13123   -2.95069  1.000 104.09546 ? 136 THR E CA  1 
ATOM   3971 C C   . THR C 3 86  ? 13.62447 9.42267   -3.31498  1.000 109.74129 ? 136 THR E C   1 
ATOM   3972 O O   . THR C 3 86  ? 12.66699 9.42211   -4.09362  1.000 107.11401 ? 136 THR E O   1 
ATOM   3973 C CB  . THR C 3 86  ? 15.61148 7.96899   -3.79607  1.000 94.21550  ? 136 THR E CB  1 
ATOM   3974 O OG1 . THR C 3 86  ? 16.44705 9.12248   -3.63638  1.000 98.40480  ? 136 THR E OG1 1 
ATOM   3975 C CG2 . THR C 3 86  ? 15.25998 7.79845   -5.26487  1.000 100.91050 ? 136 THR E CG2 1 
ATOM   3976 N N   . ALA C 3 87  ? 14.10048 10.52790  -2.73580  1.000 113.44362 ? 137 ALA E N   1 
ATOM   3977 C CA  . ALA C 3 87  ? 13.50549 11.82855  -3.02250  1.000 111.05926 ? 137 ALA E CA  1 
ATOM   3978 C C   . ALA C 3 87  ? 13.89907 12.33721  -4.40288  1.000 102.91560 ? 137 ALA E C   1 
ATOM   3979 O O   . ALA C 3 87  ? 13.17255 13.14335  -4.99462  1.000 101.83298 ? 137 ALA E O   1 
ATOM   3980 C CB  . ALA C 3 87  ? 13.90742 12.83978  -1.94914  1.000 96.72581  ? 137 ALA E CB  1 
ATOM   3981 N N   . SER C 3 88  ? 15.04048 11.88780  -4.92861  1.000 83.97677  ? 138 SER E N   1 
ATOM   3982 C CA  . SER C 3 88  ? 15.46336 12.31139  -6.25765  1.000 110.84539 ? 138 SER E CA  1 
ATOM   3983 C C   . SER C 3 88  ? 14.56405 11.75634  -7.35390  1.000 113.32280 ? 138 SER E C   1 
ATOM   3984 O O   . SER C 3 88  ? 14.51157 12.33126  -8.44637  1.000 112.68963 ? 138 SER E O   1 
ATOM   3985 C CB  . SER C 3 88  ? 16.91286 11.89304  -6.50334  1.000 117.61911 ? 138 SER E CB  1 
ATOM   3986 O OG  . SER C 3 88  ? 17.74790 12.32866  -5.44494  1.000 95.45461  ? 138 SER E OG  1 
ATOM   3987 N N   . CYS C 3 89  ? 13.86034 10.65632  -7.08879  1.000 105.80963 ? 139 CYS E N   1 
ATOM   3988 C CA  . CYS C 3 89  ? 12.89975 10.08180  -8.02154  1.000 99.68615  ? 139 CYS E CA  1 
ATOM   3989 C C   . CYS C 3 89  ? 11.46527 10.30737  -7.55323  1.000 113.33357 ? 139 CYS E C   1 
ATOM   3990 O O   . CYS C 3 89  ? 10.57443 9.50706   -7.84803  1.000 117.49414 ? 139 CYS E O   1 
ATOM   3991 C CB  . CYS C 3 89  ? 13.16984 8.59065   -8.21436  1.000 107.85671 ? 139 CYS E CB  1 
ATOM   3992 S SG  . CYS C 3 89  ? 14.78962 8.21105   -8.91957  1.000 109.46792 ? 139 CYS E SG  1 
ATOM   3993 N N   . SER C 3 90  ? 11.23525 11.39301  -6.81885  1.000 118.62584 ? 140 SER E N   1 
ATOM   3994 C CA  . SER C 3 90  ? 9.93481  11.63327  -6.20973  1.000 123.24415 ? 140 SER E CA  1 
ATOM   3995 C C   . SER C 3 90  ? 8.87076  11.90217  -7.26666  1.000 111.16363 ? 140 SER E C   1 
ATOM   3996 O O   . SER C 3 90  ? 9.12241  12.56891  -8.27433  1.000 96.34422  ? 140 SER E O   1 
ATOM   3997 C CB  . SER C 3 90  ? 10.01473 12.81036  -5.23823  1.000 117.54177 ? 140 SER E CB  1 
ATOM   3998 O OG  . SER C 3 90  ? 8.72531  13.19591  -4.79626  1.000 136.23826 ? 140 SER E OG  1 
ATOM   3999 N N   . HIS C 3 91  ? 7.67255  11.37356  -7.02680  1.000 110.23761 ? 141 HIS E N   1 
ATOM   4000 C CA  . HIS C 3 91  ? 6.52655  11.57371  -7.90221  1.000 109.41138 ? 141 HIS E CA  1 
ATOM   4001 C C   . HIS C 3 91  ? 5.37114  12.12525  -7.08224  1.000 126.02702 ? 141 HIS E C   1 
ATOM   4002 O O   . HIS C 3 91  ? 4.98238  11.52578  -6.07434  1.000 132.07536 ? 141 HIS E O   1 
ATOM   4003 C CB  . HIS C 3 91  ? 6.11690  10.26534  -8.58541  1.000 120.23015 ? 141 HIS E CB  1 
ATOM   4004 C CG  . HIS C 3 91  ? 4.88111  10.38004  -9.42229  1.000 128.54717 ? 141 HIS E CG  1 
ATOM   4005 N ND1 . HIS C 3 91  ? 3.63624  10.00147  -8.96777  1.000 124.69874 ? 141 HIS E ND1 1 
ATOM   4006 C CD2 . HIS C 3 91  ? 4.69948  10.82737  -10.68740 1.000 131.28289 ? 141 HIS E CD2 1 
ATOM   4007 C CE1 . HIS C 3 91  ? 2.74074  10.21233  -9.91586  1.000 131.24627 ? 141 HIS E CE1 1 
ATOM   4008 N NE2 . HIS C 3 91  ? 3.35988  10.71323  -10.96963 1.000 134.91464 ? 141 HIS E NE2 1 
ATOM   4009 N N   . ASN C 3 92  ? 4.82764  13.26361  -7.51885  1.000 130.70695 ? 142 ASN E N   1 
ATOM   4010 C CA  . ASN C 3 92  ? 3.70116  13.91703  -6.84796  1.000 138.17562 ? 142 ASN E CA  1 
ATOM   4011 C C   . ASN C 3 92  ? 4.01725  14.21866  -5.38379  1.000 134.14597 ? 142 ASN E C   1 
ATOM   4012 O O   . ASN C 3 92  ? 3.16450  14.08248  -4.50415  1.000 142.74026 ? 142 ASN E O   1 
ATOM   4013 C CB  . ASN C 3 92  ? 2.42512  13.07964  -6.96665  1.000 133.54586 ? 142 ASN E CB  1 
ATOM   4014 C CG  . ASN C 3 92  ? 1.80378  13.15658  -8.34733  1.000 134.04863 ? 142 ASN E CG  1 
ATOM   4015 O OD1 . ASN C 3 92  ? 2.25157  13.92263  -9.20073  1.000 125.44382 ? 142 ASN E OD1 1 
ATOM   4016 N ND2 . ASN C 3 92  ? 0.76475  12.36103  -8.57362  1.000 126.91042 ? 142 ASN E ND2 1 
ATOM   4017 N N   . GLY C 3 93  ? 5.25580  14.63039  -5.11927  1.000 132.21952 ? 143 GLY E N   1 
ATOM   4018 C CA  . GLY C 3 93  ? 5.66973  15.00807  -3.78470  1.000 134.90533 ? 143 GLY E CA  1 
ATOM   4019 C C   . GLY C 3 93  ? 6.00269  13.86233  -2.85476  1.000 136.89985 ? 143 GLY E C   1 
ATOM   4020 O O   . GLY C 3 93  ? 6.31939  14.11195  -1.68441  1.000 132.40023 ? 143 GLY E O   1 
ATOM   4021 N N   . LYS C 3 94  ? 5.94484  12.62040  -3.32768  1.000 131.34368 ? 144 LYS E N   1 
ATOM   4022 C CA  . LYS C 3 94  ? 6.25798  11.44964  -2.52161  1.000 123.92324 ? 144 LYS E CA  1 
ATOM   4023 C C   . LYS C 3 94  ? 7.45325  10.72612  -3.12321  1.000 113.58385 ? 144 LYS E C   1 
ATOM   4024 O O   . LYS C 3 94  ? 7.55479  10.59222  -4.34660  1.000 119.60292 ? 144 LYS E O   1 
ATOM   4025 C CB  . LYS C 3 94  ? 5.05931  10.49810  -2.43500  1.000 111.95285 ? 144 LYS E CB  1 
ATOM   4026 C CG  . LYS C 3 94  ? 4.43041  10.41230  -1.05437  1.000 128.06437 ? 144 LYS E CG  1 
ATOM   4027 C CD  . LYS C 3 94  ? 3.65149  11.67566  -0.72680  1.000 137.32752 ? 144 LYS E CD  1 
ATOM   4028 C CE  . LYS C 3 94  ? 2.48889  11.87040  -1.68685  1.000 136.63873 ? 144 LYS E CE  1 
ATOM   4029 N NZ  . LYS C 3 94  ? 1.74446  13.13038  -1.41211  1.000 128.88664 ? 144 LYS E NZ  1 
ATOM   4030 N N   . SER C 3 95  ? 8.35733  10.26582  -2.25958  1.000 109.22565 ? 145 SER E N   1 
ATOM   4031 C CA  . SER C 3 95  ? 9.53957  9.55211   -2.72497  1.000 107.21822 ? 145 SER E CA  1 
ATOM   4032 C C   . SER C 3 95  ? 9.13657  8.28732   -3.47134  1.000 114.22854 ? 145 SER E C   1 
ATOM   4033 O O   . SER C 3 95  ? 8.29655  7.51367   -3.00238  1.000 105.74452 ? 145 SER E O   1 
ATOM   4034 C CB  . SER C 3 95  ? 10.44843 9.20552   -1.54597  1.000 91.93428  ? 145 SER E CB  1 
ATOM   4035 O OG  . SER C 3 95  ? 11.06733 10.36625  -1.02023  1.000 100.77657 ? 145 SER E OG  1 
ATOM   4036 N N   . SER C 3 96  ? 9.74110  8.07998   -4.63794  1.000 110.18058 ? 146 SER E N   1 
ATOM   4037 C CA  . SER C 3 96  ? 9.40868  6.95174   -5.49567  1.000 110.08329 ? 146 SER E CA  1 
ATOM   4038 C C   . SER C 3 96  ? 10.69617 6.42582   -6.12025  1.000 117.07241 ? 146 SER E C   1 
ATOM   4039 O O   . SER C 3 96  ? 11.80327 6.82779   -5.74849  1.000 109.16398 ? 146 SER E O   1 
ATOM   4040 C CB  . SER C 3 96  ? 8.37504  7.36155   -6.55365  1.000 117.82675 ? 146 SER E CB  1 
ATOM   4041 O OG  . SER C 3 96  ? 7.94100  6.24134   -7.30515  1.000 118.03578 ? 146 SER E OG  1 
ATOM   4042 N N   . PHE C 3 97  ? 10.54318 5.51726   -7.07990  1.000 109.48970 ? 147 PHE E N   1 
ATOM   4043 C CA  . PHE C 3 97  ? 11.66890 4.91117   -7.77378  1.000 95.34100  ? 147 PHE E CA  1 
ATOM   4044 C C   . PHE C 3 97  ? 11.20095 4.50373   -9.16481  1.000 106.43198 ? 147 PHE E C   1 
ATOM   4045 O O   . PHE C 3 97  ? 10.04937 4.73439   -9.54490  1.000 114.05902 ? 147 PHE E O   1 
ATOM   4046 C CB  . PHE C 3 97  ? 12.22281 3.71916   -6.98443  1.000 100.69582 ? 147 PHE E CB  1 
ATOM   4047 C CG  . PHE C 3 97  ? 13.61586 3.31954   -7.38178  1.000 88.65912  ? 147 PHE E CG  1 
ATOM   4048 C CD1 . PHE C 3 97  ? 14.67906 4.18767   -7.19880  1.000 89.93979  ? 147 PHE E CD1 1 
ATOM   4049 C CD2 . PHE C 3 97  ? 13.86149 2.07459   -7.93672  1.000 85.05845  ? 147 PHE E CD2 1 
ATOM   4050 C CE1 . PHE C 3 97  ? 15.96158 3.82213   -7.56309  1.000 87.62760  ? 147 PHE E CE1 1 
ATOM   4051 C CE2 . PHE C 3 97  ? 15.14115 1.70345   -8.30339  1.000 90.14018  ? 147 PHE E CE2 1 
ATOM   4052 C CZ  . PHE C 3 97  ? 16.19259 2.57829   -8.11601  1.000 83.15677  ? 147 PHE E CZ  1 
ATOM   4053 N N   . TYR C 3 98  ? 12.10698 3.89819   -9.92918  1.000 101.83891 ? 148 TYR E N   1 
ATOM   4054 C CA  . TYR C 3 98  ? 11.76145 3.44036   -11.26696 1.000 82.28958  ? 148 TYR E CA  1 
ATOM   4055 C C   . TYR C 3 98  ? 10.67785 2.37181   -11.19893 1.000 88.39419  ? 148 TYR E C   1 
ATOM   4056 O O   . TYR C 3 98  ? 10.65190 1.54575   -10.28318 1.000 99.89977  ? 148 TYR E O   1 
ATOM   4057 C CB  . TYR C 3 98  ? 12.99789 2.89324   -11.97999 1.000 76.95700  ? 148 TYR E CB  1 
ATOM   4058 C CG  . TYR C 3 98  ? 14.09173 3.91563   -12.18406 1.000 79.60604  ? 148 TYR E CG  1 
ATOM   4059 C CD1 . TYR C 3 98  ? 13.99483 4.87472   -13.18336 1.000 93.65186  ? 148 TYR E CD1 1 
ATOM   4060 C CD2 . TYR C 3 98  ? 15.22679 3.91471   -11.38498 1.000 78.13244  ? 148 TYR E CD2 1 
ATOM   4061 C CE1 . TYR C 3 98  ? 14.99428 5.81000   -13.37495 1.000 108.08952 ? 148 TYR E CE1 1 
ATOM   4062 C CE2 . TYR C 3 98  ? 16.23175 4.84452   -11.56973 1.000 66.76317  ? 148 TYR E CE2 1 
ATOM   4063 C CZ  . TYR C 3 98  ? 16.11077 5.78942   -12.56515 1.000 92.27611  ? 148 TYR E CZ  1 
ATOM   4064 O OH  . TYR C 3 98  ? 17.11017 6.71690   -12.75043 1.000 106.35081 ? 148 TYR E OH  1 
ATOM   4065 N N   . ARG C 3 99  ? 9.76582  2.40257   -12.17145 1.000 90.87875  ? 149 ARG E N   1 
ATOM   4066 C CA  . ARG C 3 99  ? 8.68496  1.42429   -12.20260 1.000 95.45630  ? 149 ARG E CA  1 
ATOM   4067 C C   . ARG C 3 99  ? 9.16349  0.05527   -12.66905 1.000 106.22320 ? 149 ARG E C   1 
ATOM   4068 O O   . ARG C 3 99  ? 8.59335  -0.96462  -12.26567 1.000 101.66815 ? 149 ARG E O   1 
ATOM   4069 C CB  . ARG C 3 99  ? 7.54889  1.91831   -13.10156 1.000 112.54336 ? 149 ARG E CB  1 
ATOM   4070 C CG  . ARG C 3 99  ? 6.49111  2.74808   -12.38172 1.000 124.24587 ? 149 ARG E CG  1 
ATOM   4071 C CD  . ARG C 3 99  ? 7.04028  4.09122   -11.92412 1.000 132.30969 ? 149 ARG E CD  1 
ATOM   4072 N NE  . ARG C 3 99  ? 6.27224  4.65161   -10.81858 1.000 131.68449 ? 149 ARG E NE  1 
ATOM   4073 C CZ  . ARG C 3 99  ? 5.32661  5.57140   -10.95283 1.000 137.42782 ? 149 ARG E CZ  1 
ATOM   4074 N NH1 . ARG C 3 99  ? 5.00075  6.06004   -12.13840 1.000 139.91926 ? 149 ARG E NH1 1 
ATOM   4075 N NH2 . ARG C 3 99  ? 4.69232  6.01253   -9.87022  1.000 140.08559 ? 149 ARG E NH2 1 
ATOM   4076 N N   . ASN C 3 100 ? 10.19487 0.00962   -13.51188 1.000 108.93898 ? 150 ASN E N   1 
ATOM   4077 C CA  . ASN C 3 100 ? 10.71517 -1.24682  -14.03408 1.000 94.42156  ? 150 ASN E CA  1 
ATOM   4078 C C   . ASN C 3 100 ? 11.86580 -1.81110  -13.21110 1.000 84.71317  ? 150 ASN E C   1 
ATOM   4079 O O   . ASN C 3 100 ? 12.30044 -2.93705  -13.47571 1.000 89.55158  ? 150 ASN E O   1 
ATOM   4080 C CB  . ASN C 3 100 ? 11.17146 -1.06109  -15.48396 1.000 84.52478  ? 150 ASN E CB  1 
ATOM   4081 C CG  . ASN C 3 100 ? 10.07932 -0.49647  -16.36701 1.000 93.28149  ? 150 ASN E CG  1 
ATOM   4082 O OD1 . ASN C 3 100 ? 8.89809  -0.78334  -16.17247 1.000 87.75013  ? 150 ASN E OD1 1 
ATOM   4083 N ND2 . ASN C 3 100 ? 10.46736 0.32185   -17.33801 1.000 111.26414 ? 150 ASN E ND2 1 
ATOM   4084 N N   . LEU C 3 101 ? 12.36567 -1.06727  -12.22884 1.000 81.90480  ? 151 LEU E N   1 
ATOM   4085 C CA  . LEU C 3 101 ? 13.44935 -1.51624  -11.36763 1.000 84.52607  ? 151 LEU E CA  1 
ATOM   4086 C C   . LEU C 3 101 ? 13.00085 -1.45799  -9.91540  1.000 87.95880  ? 151 LEU E C   1 
ATOM   4087 O O   . LEU C 3 101 ? 12.30866 -0.52102  -9.50677  1.000 97.81583  ? 151 LEU E O   1 
ATOM   4088 C CB  . LEU C 3 101 ? 14.70609 -0.66170  -11.56109 1.000 88.33911  ? 151 LEU E CB  1 
ATOM   4089 C CG  . LEU C 3 101 ? 15.25783 -0.56706  -12.98366 1.000 85.58831  ? 151 LEU E CG  1 
ATOM   4090 C CD1 . LEU C 3 101 ? 16.49716 0.31243   -13.01714 1.000 90.06711  ? 151 LEU E CD1 1 
ATOM   4091 C CD2 . LEU C 3 101 ? 15.56604 -1.95163  -13.52495 1.000 85.57338  ? 151 LEU E CD2 1 
ATOM   4092 N N   . LEU C 3 102 ? 13.39622 -2.46135  -9.13828  1.000 83.74727  ? 152 LEU E N   1 
ATOM   4093 C CA  . LEU C 3 102 ? 13.02502 -2.55797  -7.73428  1.000 83.78752  ? 152 LEU E CA  1 
ATOM   4094 C C   . LEU C 3 102 ? 14.28238 -2.58111  -6.87828  1.000 87.51213  ? 152 LEU E C   1 
ATOM   4095 O O   . LEU C 3 102 ? 15.18587 -3.38971  -7.11599  1.000 89.57734  ? 152 LEU E O   1 
ATOM   4096 C CB  . LEU C 3 102 ? 12.17979 -3.80705  -7.47670  1.000 80.54466  ? 152 LEU E CB  1 
ATOM   4097 C CG  . LEU C 3 102 ? 11.89174 -4.14009  -6.01367  1.000 85.30469  ? 152 LEU E CG  1 
ATOM   4098 C CD1 . LEU C 3 102 ? 11.16901 -2.98685  -5.33629  1.000 92.98740  ? 152 LEU E CD1 1 
ATOM   4099 C CD2 . LEU C 3 102 ? 11.07539 -5.41273  -5.91968  1.000 90.15443  ? 152 LEU E CD2 1 
ATOM   4100 N N   . TRP C 3 103 ? 14.33730 -1.69302  -5.88885  1.000 90.63022  ? 153 TRP E N   1 
ATOM   4101 C CA  . TRP C 3 103 ? 15.46034 -1.65192  -4.96326  1.000 96.74349  ? 153 TRP E CA  1 
ATOM   4102 C C   . TRP C 3 103 ? 15.30604 -2.74852  -3.91726  1.000 100.56987 ? 153 TRP E C   1 
ATOM   4103 O O   . TRP C 3 103 ? 14.24366 -2.88811  -3.30295  1.000 107.36269 ? 153 TRP E O   1 
ATOM   4104 C CB  . TRP C 3 103 ? 15.54553 -0.28379  -4.28655  1.000 93.91096  ? 153 TRP E CB  1 
ATOM   4105 C CG  . TRP C 3 103 ? 16.89649 0.03419   -3.71204  1.000 89.00091  ? 153 TRP E CG  1 
ATOM   4106 C CD1 . TRP C 3 103 ? 17.67332 -0.78051  -2.94002  1.000 84.45843  ? 153 TRP E CD1 1 
ATOM   4107 C CD2 . TRP C 3 103 ? 17.61815 1.26539   -3.84581  1.000 88.62505  ? 153 TRP E CD2 1 
ATOM   4108 N NE1 . TRP C 3 103 ? 18.83835 -0.13888  -2.59670  1.000 88.04860  ? 153 TRP E NE1 1 
ATOM   4109 C CE2 . TRP C 3 103 ? 18.82836 1.11929   -3.13865  1.000 77.27565  ? 153 TRP E CE2 1 
ATOM   4110 C CE3 . TRP C 3 103 ? 17.36072 2.47456   -4.49892  1.000 92.31808  ? 153 TRP E CE3 1 
ATOM   4111 C CZ2 . TRP C 3 103 ? 19.77852 2.13594   -3.06653  1.000 65.38439  ? 153 TRP E CZ2 1 
ATOM   4112 C CZ3 . TRP C 3 103 ? 18.30545 3.48283   -4.42549  1.000 82.14794  ? 153 TRP E CZ3 1 
ATOM   4113 C CH2 . TRP C 3 103 ? 19.49914 3.30694   -3.71490  1.000 70.62553  ? 153 TRP E CH2 1 
ATOM   4114 N N   . LEU C 3 104 ? 16.36774 -3.52144  -3.71243  1.000 99.01318  ? 154 LEU E N   1 
ATOM   4115 C CA  . LEU C 3 104 ? 16.38068 -4.60169  -2.73652  1.000 82.91731  ? 154 LEU E CA  1 
ATOM   4116 C C   . LEU C 3 104 ? 17.21891 -4.18497  -1.53695  1.000 85.33350  ? 154 LEU E C   1 
ATOM   4117 O O   . LEU C 3 104 ? 18.37692 -3.78277  -1.69298  1.000 84.60831  ? 154 LEU E O   1 
ATOM   4118 C CB  . LEU C 3 104 ? 16.93442 -5.88962  -3.34985  1.000 91.06449  ? 154 LEU E CB  1 
ATOM   4119 C CG  . LEU C 3 104 ? 16.01766 -6.62889  -4.32661  1.000 80.90174  ? 154 LEU E CG  1 
ATOM   4120 C CD1 . LEU C 3 104 ? 16.63297 -7.95893  -4.73147  1.000 66.07335  ? 154 LEU E CD1 1 
ATOM   4121 C CD2 . LEU C 3 104 ? 14.63518 -6.83196  -3.72516  1.000 77.49224  ? 154 LEU E CD2 1 
ATOM   4122 N N   . THR C 3 105 ? 16.63265 -4.28066  -0.34778  1.000 90.33825  ? 155 THR E N   1 
ATOM   4123 C CA  . THR C 3 105 ? 17.29555 -3.92604  0.89737   1.000 80.61514  ? 155 THR E CA  1 
ATOM   4124 C C   . THR C 3 105 ? 17.29158 -5.12036  1.84366   1.000 83.90285  ? 155 THR E C   1 
ATOM   4125 O O   . THR C 3 105 ? 16.67083 -6.15404  1.58140   1.000 80.36360  ? 155 THR E O   1 
ATOM   4126 C CB  . THR C 3 105 ? 16.61919 -2.72111  1.56726   1.000 83.09055  ? 155 THR E CB  1 
ATOM   4127 O OG1 . THR C 3 105 ? 15.33198 -3.10774  2.06534   1.000 95.34805  ? 155 THR E OG1 1 
ATOM   4128 C CG2 . THR C 3 105 ? 16.45445 -1.57519  0.57820   1.000 72.03235  ? 155 THR E CG2 1 
ATOM   4129 N N   . GLU C 3 106 ? 17.99939 -4.96326  2.95849   1.000 87.83370  ? 156 GLU E N   1 
ATOM   4130 C CA  . GLU C 3 106 ? 18.06620 -6.01152  3.96304   1.000 79.11127  ? 156 GLU E CA  1 
ATOM   4131 C C   . GLU C 3 106 ? 16.71906 -6.17636  4.66109   1.000 82.81833  ? 156 GLU E C   1 
ATOM   4132 O O   . GLU C 3 106 ? 15.88339 -5.26829  4.68751   1.000 87.48225  ? 156 GLU E O   1 
ATOM   4133 C CB  . GLU C 3 106 ? 19.15222 -5.69876  4.99258   1.000 74.60665  ? 156 GLU E CB  1 
ATOM   4134 C CG  . GLU C 3 106 ? 18.97438 -4.35877  5.69489   1.000 72.49241  ? 156 GLU E CG  1 
ATOM   4135 C CD  . GLU C 3 106 ? 18.14494 -4.46476  6.95954   1.000 79.67357  ? 156 GLU E CD  1 
ATOM   4136 O OE1 . GLU C 3 106 ? 18.31310 -5.45504  7.69937   1.000 84.48329  ? 156 GLU E OE1 1 
ATOM   4137 O OE2 . GLU C 3 106 ? 17.32202 -3.56006  7.21171   1.000 75.45225  ? 156 GLU E OE2 1 
ATOM   4138 N N   . LYS C 3 107 ? 16.51280 -7.36254  5.22855   1.000 77.27234  ? 157 LYS E N   1 
ATOM   4139 C CA  . LYS C 3 107 ? 15.31700 -7.66038  6.00393   1.000 73.76413  ? 157 LYS E CA  1 
ATOM   4140 C C   . LYS C 3 107 ? 15.72243 -8.29943  7.32211   1.000 81.33571  ? 157 LYS E C   1 
ATOM   4141 O O   . LYS C 3 107 ? 16.47310 -9.28068  7.33339   1.000 73.38765  ? 157 LYS E O   1 
ATOM   4142 C CB  . LYS C 3 107 ? 14.36733 -8.58663  5.23730   1.000 71.19825  ? 157 LYS E CB  1 
ATOM   4143 C CG  . LYS C 3 107 ? 13.03342 -8.80899  5.93216   1.000 59.81115  ? 157 LYS E CG  1 
ATOM   4144 C CD  . LYS C 3 107 ? 12.12462 -9.71488  5.11840   1.000 79.28661  ? 157 LYS E CD  1 
ATOM   4145 C CE  . LYS C 3 107 ? 10.76708 -9.87399  5.78440   1.000 76.68521  ? 157 LYS E CE  1 
ATOM   4146 N NZ  . LYS C 3 107 ? 9.87963  -10.79861 5.02665   1.000 87.78575  ? 157 LYS E NZ  1 
ATOM   4147 N N   . ASN C 3 108 ? 15.21905 -7.74001  8.42491   1.000 85.97384  ? 158 ASN E N   1 
ATOM   4148 C CA  . ASN C 3 108 ? 15.44071 -8.27774  9.76909   1.000 74.46806  ? 158 ASN E CA  1 
ATOM   4149 C C   . ASN C 3 108 ? 16.92866 -8.41951  10.08684  1.000 79.25304  ? 158 ASN E C   1 
ATOM   4150 O O   . ASN C 3 108 ? 17.37246 -9.43004  10.63595  1.000 72.41870  ? 158 ASN E O   1 
ATOM   4151 C CB  . ASN C 3 108 ? 14.71441 -9.61195  9.95269   1.000 64.78083  ? 158 ASN E CB  1 
ATOM   4152 C CG  . ASN C 3 108 ? 13.20650 -9.46104  9.91990   1.000 78.88427  ? 158 ASN E CG  1 
ATOM   4153 O OD1 . ASN C 3 108 ? 12.68487 -8.34949  9.83018   1.000 83.12354  ? 158 ASN E OD1 1 
ATOM   4154 N ND2 . ASN C 3 108 ? 12.49712 -10.58100 9.99295   1.000 90.07297  ? 158 ASN E ND2 1 
ATOM   4155 N N   . GLY C 3 109 ? 17.70794 -7.40078  9.73171   1.000 75.88593  ? 159 GLY E N   1 
ATOM   4156 C CA  . GLY C 3 109 ? 19.10879 -7.35856  10.09615  1.000 66.40954  ? 159 GLY E CA  1 
ATOM   4157 C C   . GLY C 3 109 ? 20.02284 -8.24833  9.28803   1.000 78.33028  ? 159 GLY E C   1 
ATOM   4158 O O   . GLY C 3 109 ? 21.19643 -8.38990  9.64991   1.000 82.01147  ? 159 GLY E O   1 
ATOM   4159 N N   . LEU C 3 110 ? 19.53138 -8.85570  8.21045   1.000 79.88859  ? 160 LEU E N   1 
ATOM   4160 C CA  . LEU C 3 110 ? 20.34936 -9.72367  7.37804   1.000 84.43549  ? 160 LEU E CA  1 
ATOM   4161 C C   . LEU C 3 110 ? 19.99057 -9.51638  5.91444   1.000 93.73092  ? 160 LEU E C   1 
ATOM   4162 O O   . LEU C 3 110 ? 18.86570 -9.13460  5.58041   1.000 87.15848  ? 160 LEU E O   1 
ATOM   4163 C CB  . LEU C 3 110 ? 20.17338 -11.20173 7.75534   1.000 90.49978  ? 160 LEU E CB  1 
ATOM   4164 C CG  . LEU C 3 110 ? 20.95547 -11.69354 8.97523   1.000 84.04843  ? 160 LEU E CG  1 
ATOM   4165 C CD1 . LEU C 3 110 ? 20.46552 -13.06662 9.40877   1.000 74.25556  ? 160 LEU E CD1 1 
ATOM   4166 C CD2 . LEU C 3 110 ? 22.44871 -11.71818 8.68582   1.000 68.67241  ? 160 LEU E CD2 1 
ATOM   4167 N N   . TYR C 3 111 ? 20.96526 -9.77550  5.04432   1.000 87.84777  ? 161 TYR E N   1 
ATOM   4168 C CA  . TYR C 3 111 ? 20.78794 -9.71282  3.59399   1.000 82.36132  ? 161 TYR E CA  1 
ATOM   4169 C C   . TYR C 3 111 ? 21.27215 -11.03842 3.02331   1.000 91.61967  ? 161 TYR E C   1 
ATOM   4170 O O   . TYR C 3 111 ? 22.42124 -11.15458 2.57470   1.000 84.89415  ? 161 TYR E O   1 
ATOM   4171 C CB  . TYR C 3 111 ? 21.54040 -8.52640  2.98785   1.000 83.99679  ? 161 TYR E CB  1 
ATOM   4172 C CG  . TYR C 3 111 ? 21.10130 -8.15430  1.58476   1.000 89.42703  ? 161 TYR E CG  1 
ATOM   4173 C CD1 . TYR C 3 111 ? 21.30255 -9.02010  0.51624   1.000 75.43882  ? 161 TYR E CD1 1 
ATOM   4174 C CD2 . TYR C 3 111 ? 20.49102 -6.93291  1.32910   1.000 85.59997  ? 161 TYR E CD2 1 
ATOM   4175 C CE1 . TYR C 3 111 ? 20.90542 -8.68358  -0.76365  1.000 80.30326  ? 161 TYR E CE1 1 
ATOM   4176 C CE2 . TYR C 3 111 ? 20.09051 -6.58696  0.05073   1.000 90.37656  ? 161 TYR E CE2 1 
ATOM   4177 C CZ  . TYR C 3 111 ? 20.30071 -7.46639  -0.99176  1.000 92.21883  ? 161 TYR E CZ  1 
ATOM   4178 O OH  . TYR C 3 111 ? 19.90580 -7.12882  -2.26687  1.000 70.86912  ? 161 TYR E OH  1 
ATOM   4179 N N   . PRO C 3 112 ? 20.42237 -12.06501 3.03473   1.000 93.24038  ? 162 PRO E N   1 
ATOM   4180 C CA  . PRO C 3 112 ? 20.85006 -13.38203 2.55101   1.000 82.66472  ? 162 PRO E CA  1 
ATOM   4181 C C   . PRO C 3 112 ? 21.20756 -13.34666 1.07386   1.000 85.08913  ? 162 PRO E C   1 
ATOM   4182 O O   . PRO C 3 112 ? 20.67599 -12.54573 0.30157   1.000 98.47899  ? 162 PRO E O   1 
ATOM   4183 C CB  . PRO C 3 112 ? 19.62378 -14.26821 2.80592   1.000 88.18240  ? 162 PRO E CB  1 
ATOM   4184 C CG  . PRO C 3 112 ? 18.83919 -13.53768 3.85750   1.000 93.10031  ? 162 PRO E CG  1 
ATOM   4185 C CD  . PRO C 3 112 ? 19.03874 -12.08971 3.53560   1.000 85.79806  ? 162 PRO E CD  1 
ATOM   4186 N N   . ASN C 3 113 ? 22.13446 -14.22250 0.69005   1.000 88.30474  ? 163 ASN E N   1 
ATOM   4187 C CA  . ASN C 3 113 ? 22.49304 -14.35532 -0.71485  1.000 85.46317  ? 163 ASN E CA  1 
ATOM   4188 C C   . ASN C 3 113 ? 21.27840 -14.78451 -1.52722  1.000 77.99690  ? 163 ASN E C   1 
ATOM   4189 O O   . ASN C 3 113 ? 20.50948 -15.65727 -1.11449  1.000 67.03381  ? 163 ASN E O   1 
ATOM   4190 C CB  . ASN C 3 113 ? 23.62775 -15.36649 -0.88454  1.000 66.90714  ? 163 ASN E CB  1 
ATOM   4191 C CG  . ASN C 3 113 ? 24.88097 -14.96804 -0.13184  1.000 100.61200 ? 163 ASN E CG  1 
ATOM   4192 O OD1 . ASN C 3 113 ? 24.90776 -13.94764 0.55660   1.000 121.74720 ? 163 ASN E OD1 1 
ATOM   4193 N ND2 . ASN C 3 113 ? 25.92973 -15.77274 -0.26110  1.000 98.67287  ? 163 ASN E ND2 1 
ATOM   4194 N N   . LEU C 3 114 ? 21.10566 -14.15972 -2.68803  1.000 87.38197  ? 164 LEU E N   1 
ATOM   4195 C CA  . LEU C 3 114 ? 19.95418 -14.39735 -3.54296  1.000 83.36389  ? 164 LEU E CA  1 
ATOM   4196 C C   . LEU C 3 114 ? 20.39935 -15.00376 -4.86632  1.000 78.49750  ? 164 LEU E C   1 
ATOM   4197 O O   . LEU C 3 114 ? 21.49183 -14.71740 -5.36571  1.000 82.66802  ? 164 LEU E O   1 
ATOM   4198 C CB  . LEU C 3 114 ? 19.16597 -13.09660 -3.78464  1.000 57.61670  ? 164 LEU E CB  1 
ATOM   4199 C CG  . LEU C 3 114 ? 19.85268 -11.91034 -4.47377  1.000 67.27576  ? 164 LEU E CG  1 
ATOM   4200 C CD1 . LEU C 3 114 ? 19.72637 -11.96612 -5.99251  1.000 73.76324  ? 164 LEU E CD1 1 
ATOM   4201 C CD2 . LEU C 3 114 ? 19.30117 -10.59650 -3.93936  1.000 78.97583  ? 164 LEU E CD2 1 
ATOM   4202 N N   . SER C 3 115 ? 19.53971 -15.85470 -5.42516  1.000 75.31636  ? 165 SER E N   1 
ATOM   4203 C CA  . SER C 3 115 ? 19.78108 -16.47988 -6.72564  1.000 72.83864  ? 165 SER E CA  1 
ATOM   4204 C C   . SER C 3 115 ? 18.43095 -16.61211 -7.42311  1.000 74.87484  ? 165 SER E C   1 
ATOM   4205 O O   . SER C 3 115 ? 17.64528 -17.50867 -7.10185  1.000 93.04339  ? 165 SER E O   1 
ATOM   4206 C CB  . SER C 3 115 ? 20.46872 -17.83175 -6.57653  1.000 79.96972  ? 165 SER E CB  1 
ATOM   4207 O OG  . SER C 3 115 ? 20.61676 -18.46917 -7.83363  1.000 87.37119  ? 165 SER E OG  1 
ATOM   4208 N N   . LYS C 3 116 ? 18.16492 -15.71591 -8.37040  1.000 60.68008  ? 166 LYS E N   1 
ATOM   4209 C CA  . LYS C 3 116 ? 16.91324 -15.70424 -9.11276  1.000 78.22337  ? 166 LYS E CA  1 
ATOM   4210 C C   . LYS C 3 116 ? 17.20870 -15.75649 -10.60361 1.000 78.84317  ? 166 LYS E C   1 
ATOM   4211 O O   . LYS C 3 116 ? 18.16324 -15.13329 -11.07814 1.000 76.08509  ? 166 LYS E O   1 
ATOM   4212 C CB  . LYS C 3 116 ? 16.08069 -14.45901 -8.78478  1.000 80.51831  ? 166 LYS E CB  1 
ATOM   4213 C CG  . LYS C 3 116 ? 14.59822 -14.60905 -9.08216  1.000 75.53833  ? 166 LYS E CG  1 
ATOM   4214 C CD  . LYS C 3 116 ? 13.93622 -15.56821 -8.10741  1.000 78.20298  ? 166 LYS E CD  1 
ATOM   4215 C CE  . LYS C 3 116 ? 12.44644 -15.69028 -8.38033  1.000 88.30240  ? 166 LYS E CE  1 
ATOM   4216 N NZ  . LYS C 3 116 ? 11.76908 -16.55833 -7.37791  1.000 107.72807 ? 166 LYS E NZ  1 
ATOM   4217 N N   . SER C 3 117 ? 16.38724 -16.50358 -11.33839 1.000 64.63129  ? 167 SER E N   1 
ATOM   4218 C CA  . SER C 3 117 ? 16.57878 -16.67594 -12.76951 1.000 73.04216  ? 167 SER E CA  1 
ATOM   4219 C C   . SER C 3 117 ? 15.23658 -16.60591 -13.48278 1.000 74.45700  ? 167 SER E C   1 
ATOM   4220 O O   . SER C 3 117 ? 14.18950 -16.90343 -12.90196 1.000 74.89523  ? 167 SER E O   1 
ATOM   4221 C CB  . SER C 3 117 ? 17.27614 -18.00658 -13.08690 1.000 74.43261  ? 167 SER E CB  1 
ATOM   4222 O OG  . SER C 3 117 ? 16.58990 -19.09746 -12.49872 1.000 80.77636  ? 167 SER E OG  1 
ATOM   4223 N N   . TYR C 3 118 ? 15.28055 -16.20180 -14.75177 1.000 79.09908  ? 168 TYR E N   1 
ATOM   4224 C CA  . TYR C 3 118 ? 14.10087 -16.13976 -15.60486 1.000 84.01271  ? 168 TYR E CA  1 
ATOM   4225 C C   . TYR C 3 118 ? 14.36691 -16.89837 -16.89481 1.000 82.96067  ? 168 TYR E C   1 
ATOM   4226 O O   . TYR C 3 118 ? 15.37463 -16.65306 -17.56537 1.000 76.19503  ? 168 TYR E O   1 
ATOM   4227 C CB  . TYR C 3 118 ? 13.71343 -14.69432 -15.93041 1.000 74.42893  ? 168 TYR E CB  1 
ATOM   4228 C CG  . TYR C 3 118 ? 12.54321 -14.59437 -16.88302 1.000 69.75666  ? 168 TYR E CG  1 
ATOM   4229 C CD1 . TYR C 3 118 ? 11.25924 -14.92794 -16.47382 1.000 77.91971  ? 168 TYR E CD1 1 
ATOM   4230 C CD2 . TYR C 3 118 ? 12.72620 -14.18617 -18.19828 1.000 89.70858  ? 168 TYR E CD2 1 
ATOM   4231 C CE1 . TYR C 3 118 ? 10.18741 -14.84467 -17.34333 1.000 88.51745  ? 168 TYR E CE1 1 
ATOM   4232 C CE2 . TYR C 3 118 ? 11.66072 -14.10083 -19.07602 1.000 80.19425  ? 168 TYR E CE2 1 
ATOM   4233 C CZ  . TYR C 3 118 ? 10.39389 -14.43132 -18.64286 1.000 92.50617  ? 168 TYR E CZ  1 
ATOM   4234 O OH  . TYR C 3 118 ? 9.32984  -14.34801 -19.51160 1.000 97.98617  ? 168 TYR E OH  1 
ATOM   4235 N N   . VAL C 3 119 ? 13.45297 -17.79821 -17.24900 1.000 92.26034  ? 169 VAL E N   1 
ATOM   4236 C CA  . VAL C 3 119 ? 13.53442 -18.57017 -18.48346 1.000 86.46436  ? 169 VAL E CA  1 
ATOM   4237 C C   . VAL C 3 119 ? 12.60358 -17.93727 -19.50705 1.000 95.00445  ? 169 VAL E C   1 
ATOM   4238 O O   . VAL C 3 119 ? 11.43362 -17.66420 -19.20947 1.000 100.12171 ? 169 VAL E O   1 
ATOM   4239 C CB  . VAL C 3 119 ? 13.17203 -20.04561 -18.24523 1.000 70.55628  ? 169 VAL E CB  1 
ATOM   4240 C CG1 . VAL C 3 119 ? 13.53178 -20.88011 -19.46268 1.000 94.76474  ? 169 VAL E CG1 1 
ATOM   4241 C CG2 . VAL C 3 119 ? 13.87762 -20.57087 -17.00571 1.000 69.72111  ? 169 VAL E CG2 1 
ATOM   4242 N N   . ASN C 3 120 ? 13.11898 -17.70303 -20.71142 1.000 81.02882  ? 170 ASN E N   1 
ATOM   4243 C CA  . ASN C 3 120 ? 12.37212 -17.01562 -21.75972 1.000 91.61526  ? 170 ASN E CA  1 
ATOM   4244 C C   . ASN C 3 120 ? 11.61651 -18.04842 -22.58934 1.000 91.09158  ? 170 ASN E C   1 
ATOM   4245 O O   . ASN C 3 120 ? 12.22588 -18.84556 -23.31001 1.000 101.28718 ? 170 ASN E O   1 
ATOM   4246 C CB  . ASN C 3 120 ? 13.31345 -16.18777 -22.63170 1.000 96.70429  ? 170 ASN E CB  1 
ATOM   4247 C CG  . ASN C 3 120 ? 12.57601 -15.34081 -23.65425 1.000 86.38494  ? 170 ASN E CG  1 
ATOM   4248 O OD1 . ASN C 3 120 ? 11.34573 -15.33091 -23.70474 1.000 93.09937  ? 170 ASN E OD1 1 
ATOM   4249 N ND2 . ASN C 3 120 ? 13.33095 -14.62189 -24.47669 1.000 79.99186  ? 170 ASN E ND2 1 
ATOM   4250 N N   . ASN C 3 121 ? 10.28630 -18.03127 -22.48701 1.000 90.81490  ? 171 ASN E N   1 
ATOM   4251 C CA  . ASN C 3 121 ? 9.42091  -18.88116 -23.29700 1.000 100.79261 ? 171 ASN E CA  1 
ATOM   4252 C C   . ASN C 3 121 ? 8.44693  -18.05817 -24.13256 1.000 105.77566 ? 171 ASN E C   1 
ATOM   4253 O O   . ASN C 3 121 ? 7.44651  -18.59199 -24.62218 1.000 99.63136  ? 171 ASN E O   1 
ATOM   4254 C CB  . ASN C 3 121 ? 8.65889  -19.87106 -22.41381 1.000 105.90421 ? 171 ASN E CB  1 
ATOM   4255 C CG  . ASN C 3 121 ? 8.20494  -19.25484 -21.10489 1.000 122.64383 ? 171 ASN E CG  1 
ATOM   4256 O OD1 . ASN C 3 121 ? 7.86706  -18.07238 -21.04524 1.000 122.26266 ? 171 ASN E OD1 1 
ATOM   4257 N ND2 . ASN C 3 121 ? 8.19397  -20.05661 -20.04656 1.000 120.41073 ? 171 ASN E ND2 1 
ATOM   4258 N N   . LYS C 3 122 ? 8.72369  -16.76681 -24.30509 1.000 108.30312 ? 172 LYS E N   1 
ATOM   4259 C CA  . LYS C 3 122 ? 7.84167  -15.85967 -25.02740 1.000 108.28787 ? 172 LYS E CA  1 
ATOM   4260 C C   . LYS C 3 122 ? 8.03060  -15.91763 -26.53758 1.000 115.37103 ? 172 LYS E C   1 
ATOM   4261 O O   . LYS C 3 122 ? 7.29447  -15.23511 -27.25938 1.000 120.79909 ? 172 LYS E O   1 
ATOM   4262 C CB  . LYS C 3 122 ? 8.06365  -14.42294 -24.54375 1.000 106.47293 ? 172 LYS E CB  1 
ATOM   4263 C CG  . LYS C 3 122 ? 8.14125  -14.27261 -23.03168 1.000 91.58374  ? 172 LYS E CG  1 
ATOM   4264 C CD  . LYS C 3 122 ? 6.76999  -14.37311 -22.38548 1.000 101.64206 ? 172 LYS E CD  1 
ATOM   4265 C CE  . LYS C 3 122 ? 5.97909  -13.08832 -22.57834 1.000 102.75465 ? 172 LYS E CE  1 
ATOM   4266 N NZ  . LYS C 3 122 ? 4.65562  -13.13750 -21.89790 1.000 97.20814  ? 172 LYS E NZ  1 
ATOM   4267 N N   . GLU C 3 123 ? 8.99819  -16.69440 -27.02587 1.000 108.55653 ? 173 GLU E N   1 
ATOM   4268 C CA  . GLU C 3 123 ? 9.36521  -16.78361 -28.43772 1.000 109.49242 ? 173 GLU E CA  1 
ATOM   4269 C C   . GLU C 3 123 ? 9.84130  -15.45205 -29.00596 1.000 102.25407 ? 173 GLU E C   1 
ATOM   4270 O O   . GLU C 3 123 ? 9.98698  -15.31998 -30.22743 1.000 100.53089 ? 173 GLU E O   1 
ATOM   4271 C CB  . GLU C 3 123 ? 8.21234  -17.33220 -29.29103 1.000 99.65554  ? 173 GLU E CB  1 
ATOM   4272 C CG  . GLU C 3 123 ? 7.82612  -18.76570 -28.96484 1.000 119.71945 ? 173 GLU E CG  1 
ATOM   4273 C CD  . GLU C 3 123 ? 6.65746  -19.25790 -29.79562 1.000 128.26845 ? 173 GLU E CD  1 
ATOM   4274 O OE1 . GLU C 3 123 ? 6.24039  -18.53450 -30.72451 1.000 131.40659 ? 173 GLU E OE1 1 
ATOM   4275 O OE2 . GLU C 3 123 ? 6.15567  -20.36798 -29.51951 1.000 128.96706 ? 173 GLU E OE2 1 
ATOM   4276 N N   . LYS C 3 124 ? 10.08702 -14.46225 -28.15034 1.000 102.48244 ? 174 LYS E N   1 
ATOM   4277 C CA  . LYS C 3 124 ? 10.56794 -13.15234 -28.55759 1.000 100.98855 ? 174 LYS E CA  1 
ATOM   4278 C C   . LYS C 3 124 ? 11.72870 -12.75139 -27.66059 1.000 90.16882  ? 174 LYS E C   1 
ATOM   4279 O O   . LYS C 3 124 ? 11.78721 -13.13651 -26.48973 1.000 90.20145  ? 174 LYS E O   1 
ATOM   4280 C CB  . LYS C 3 124 ? 9.45775  -12.09258 -28.47744 1.000 99.21112  ? 174 LYS E CB  1 
ATOM   4281 C CG  . LYS C 3 124 ? 8.15991  -12.48854 -29.16365 1.000 105.40076 ? 174 LYS E CG  1 
ATOM   4282 C CD  . LYS C 3 124 ? 6.97411  -11.73804 -28.57853 1.000 105.02932 ? 174 LYS E CD  1 
ATOM   4283 C CE  . LYS C 3 124 ? 7.15992  -10.23431 -28.68996 1.000 116.60740 ? 174 LYS E CE  1 
ATOM   4284 N NZ  . LYS C 3 124 ? 5.88062  -9.49868  -28.48754 1.000 115.86489 ? 174 LYS E NZ  1 
ATOM   4285 N N   . GLU C 3 125 ? 12.65716 -11.97949 -28.22047 1.000 94.13481  ? 175 GLU E N   1 
ATOM   4286 C CA  . GLU C 3 125 ? 13.78802 -11.50316 -27.43649 1.000 91.67141  ? 175 GLU E CA  1 
ATOM   4287 C C   . GLU C 3 125 ? 13.30540 -10.59183 -26.31475 1.000 99.50085  ? 175 GLU E C   1 
ATOM   4288 O O   . GLU C 3 125 ? 12.44429 -9.73093  -26.51583 1.000 107.75152 ? 175 GLU E O   1 
ATOM   4289 C CB  . GLU C 3 125 ? 14.78650 -10.76925 -28.33149 1.000 88.88429  ? 175 GLU E CB  1 
ATOM   4290 C CG  . GLU C 3 125 ? 15.84330 -11.67930 -28.93651 1.000 86.62021  ? 175 GLU E CG  1 
ATOM   4291 C CD  . GLU C 3 125 ? 17.02082 -10.91353 -29.50378 1.000 99.99952  ? 175 GLU E CD  1 
ATOM   4292 O OE1 . GLU C 3 125 ? 16.87814 -9.69800  -29.75357 1.000 103.04929 ? 175 GLU E OE1 1 
ATOM   4293 O OE2 . GLU C 3 125 ? 18.09107 -11.52779 -29.69646 1.000 105.37096 ? 175 GLU E OE2 1 
ATOM   4294 N N   . VAL C 3 126 ? 13.86768 -10.78720 -25.12504 1.000 99.62856  ? 176 VAL E N   1 
ATOM   4295 C CA  . VAL C 3 126 ? 13.42065 -10.11257 -23.91218 1.000 95.71946  ? 176 VAL E CA  1 
ATOM   4296 C C   . VAL C 3 126 ? 14.49211 -9.12221  -23.48035 1.000 87.22307  ? 176 VAL E C   1 
ATOM   4297 O O   . VAL C 3 126 ? 15.66544 -9.48788  -23.33751 1.000 81.62703  ? 176 VAL E O   1 
ATOM   4298 C CB  . VAL C 3 126 ? 13.11748 -11.12089 -22.78999 1.000 82.39658  ? 176 VAL E CB  1 
ATOM   4299 C CG1 . VAL C 3 126 ? 13.08443 -10.42348 -21.43949 1.000 98.05299  ? 176 VAL E CG1 1 
ATOM   4300 C CG2 . VAL C 3 126 ? 11.80223 -11.83567 -23.06093 1.000 90.59885  ? 176 VAL E CG2 1 
ATOM   4301 N N   . LEU C 3 127 ? 14.08793 -7.87155  -23.27366 1.000 86.90844  ? 177 LEU E N   1 
ATOM   4302 C CA  . LEU C 3 127 ? 14.98496 -6.83186  -22.78754 1.000 84.97945  ? 177 LEU E CA  1 
ATOM   4303 C C   . LEU C 3 127 ? 14.97545 -6.83923  -21.26363 1.000 99.01420  ? 177 LEU E C   1 
ATOM   4304 O O   . LEU C 3 127 ? 13.92266 -6.65363  -20.64305 1.000 99.28220  ? 177 LEU E O   1 
ATOM   4305 C CB  . LEU C 3 127 ? 14.56669 -5.46304  -23.32237 1.000 85.16218  ? 177 LEU E CB  1 
ATOM   4306 C CG  . LEU C 3 127 ? 15.43313 -4.27621  -22.89591 1.000 75.23295  ? 177 LEU E CG  1 
ATOM   4307 C CD1 . LEU C 3 127 ? 16.88093 -4.49135  -23.30498 1.000 63.41504  ? 177 LEU E CD1 1 
ATOM   4308 C CD2 . LEU C 3 127 ? 14.89316 -2.97799  -23.47636 1.000 79.40208  ? 177 LEU E CD2 1 
ATOM   4309 N N   . VAL C 3 128 ? 16.14425 -7.05203  -20.66503 1.000 100.20920 ? 178 VAL E N   1 
ATOM   4310 C CA  . VAL C 3 128 ? 16.29907 -7.10100  -19.21645 1.000 78.27944  ? 178 VAL E CA  1 
ATOM   4311 C C   . VAL C 3 128 ? 17.24499 -5.98567  -18.79767 1.000 80.07334  ? 178 VAL E C   1 
ATOM   4312 O O   . VAL C 3 128 ? 18.36904 -5.89444  -19.30485 1.000 75.57994  ? 178 VAL E O   1 
ATOM   4313 C CB  . VAL C 3 128 ? 16.82459 -8.46955  -18.74533 1.000 81.03256  ? 178 VAL E CB  1 
ATOM   4314 C CG1 . VAL C 3 128 ? 17.08800 -8.45046  -17.24741 1.000 95.10827  ? 178 VAL E CG1 1 
ATOM   4315 C CG2 . VAL C 3 128 ? 15.83520 -9.56755  -19.10061 1.000 74.02031  ? 178 VAL E CG2 1 
ATOM   4316 N N   . LEU C 3 129 ? 16.78917 -5.14206  -17.87612 1.000 86.82698  ? 179 LEU E N   1 
ATOM   4317 C CA  . LEU C 3 129 ? 17.57936 -4.03954  -17.34992 1.000 87.64324  ? 179 LEU E CA  1 
ATOM   4318 C C   . LEU C 3 129 ? 17.67159 -4.15629  -15.83556 1.000 80.03853  ? 179 LEU E C   1 
ATOM   4319 O O   . LEU C 3 129 ? 16.69897 -4.52878  -15.17215 1.000 75.45294  ? 179 LEU E O   1 
ATOM   4320 C CB  . LEU C 3 129 ? 16.97143 -2.68625  -17.73500 1.000 81.63096  ? 179 LEU E CB  1 
ATOM   4321 C CG  . LEU C 3 129 ? 16.55320 -2.51105  -19.19599 1.000 74.19953  ? 179 LEU E CG  1 
ATOM   4322 C CD1 . LEU C 3 129 ? 15.04271 -2.61629  -19.34027 1.000 80.33380  ? 179 LEU E CD1 1 
ATOM   4323 C CD2 . LEU C 3 129 ? 17.05461 -1.18234  -19.73923 1.000 78.24619  ? 179 LEU E CD2 1 
ATOM   4324 N N   . TRP C 3 130 ? 18.84623 -3.84134  -15.29492 1.000 82.57317  ? 180 TRP E N   1 
ATOM   4325 C CA  . TRP C 3 130 ? 19.07300 -3.87649  -13.85740 1.000 89.90107  ? 180 TRP E CA  1 
ATOM   4326 C C   . TRP C 3 130 ? 20.06437 -2.77753  -13.49682 1.000 88.39190  ? 180 TRP E C   1 
ATOM   4327 O O   . TRP C 3 130 ? 20.52096 -2.01773  -14.35570 1.000 90.16915  ? 180 TRP E O   1 
ATOM   4328 C CB  . TRP C 3 130 ? 19.57358 -5.25344  -13.40830 1.000 82.16931  ? 180 TRP E CB  1 
ATOM   4329 C CG  . TRP C 3 130 ? 20.94251 -5.58835  -13.91536 1.000 79.76711  ? 180 TRP E CG  1 
ATOM   4330 C CD1 . TRP C 3 130 ? 22.12949 -5.37360  -13.27695 1.000 69.51904  ? 180 TRP E CD1 1 
ATOM   4331 C CD2 . TRP C 3 130 ? 21.26683 -6.19551  -15.17139 1.000 85.81191  ? 180 TRP E CD2 1 
ATOM   4332 N NE1 . TRP C 3 130 ? 23.17254 -5.81120  -14.05686 1.000 71.00746  ? 180 TRP E NE1 1 
ATOM   4333 C CE2 . TRP C 3 130 ? 22.66941 -6.32007  -15.22534 1.000 83.79283  ? 180 TRP E CE2 1 
ATOM   4334 C CE3 . TRP C 3 130 ? 20.50736 -6.64705  -16.25480 1.000 75.34926  ? 180 TRP E CE3 1 
ATOM   4335 C CZ2 . TRP C 3 130 ? 23.32750 -6.87702  -16.31980 1.000 75.88283  ? 180 TRP E CZ2 1 
ATOM   4336 C CZ3 . TRP C 3 130 ? 21.16224 -7.19912  -17.33928 1.000 81.76033  ? 180 TRP E CZ3 1 
ATOM   4337 C CH2 . TRP C 3 130 ? 22.55794 -7.30956  -17.36419 1.000 79.30656  ? 180 TRP E CH2 1 
ATOM   4338 N N   . GLY C 3 131 ? 20.39654 -2.69722  -12.21141 1.000 88.84102  ? 181 GLY E N   1 
ATOM   4339 C CA  . GLY C 3 131 ? 21.33202 -1.69352  -11.74116 1.000 83.63447  ? 181 GLY E CA  1 
ATOM   4340 C C   . GLY C 3 131 ? 22.14546 -2.20202  -10.57150 1.000 82.68289  ? 181 GLY E C   1 
ATOM   4341 O O   . GLY C 3 131 ? 21.74598 -3.13130  -9.86188  1.000 76.16816  ? 181 GLY E O   1 
ATOM   4342 N N   . VAL C 3 132 ? 23.30479 -1.57705  -10.38220 1.000 88.73202  ? 182 VAL E N   1 
ATOM   4343 C CA  . VAL C 3 132 ? 24.20469 -1.87922  -9.27480  1.000 82.18617  ? 182 VAL E CA  1 
ATOM   4344 C C   . VAL C 3 132 ? 24.45704 -0.58516  -8.51389  1.000 86.08854  ? 182 VAL E C   1 
ATOM   4345 O O   . VAL C 3 132 ? 24.88707 0.41447   -9.10334  1.000 76.46826  ? 182 VAL E O   1 
ATOM   4346 C CB  . VAL C 3 132 ? 25.52409 -2.49956  -9.76050  1.000 72.36142  ? 182 VAL E CB  1 
ATOM   4347 C CG1 . VAL C 3 132 ? 26.49038 -2.67084  -8.59762  1.000 84.71456  ? 182 VAL E CG1 1 
ATOM   4348 C CG2 . VAL C 3 132 ? 25.26181 -3.83397  -10.44265 1.000 63.24989  ? 182 VAL E CG2 1 
ATOM   4349 N N   . HIS C 3 133 ? 24.19202 -0.60457  -7.21034  1.000 95.58688  ? 183 HIS E N   1 
ATOM   4350 C CA  . HIS C 3 133 ? 24.34480 0.58412   -6.38402  1.000 87.69158  ? 183 HIS E CA  1 
ATOM   4351 C C   . HIS C 3 133 ? 25.78992 0.75879   -5.93636  1.000 86.21981  ? 183 HIS E C   1 
ATOM   4352 O O   . HIS C 3 133 ? 26.46498 -0.20647  -5.56733  1.000 88.31651  ? 183 HIS E O   1 
ATOM   4353 C CB  . HIS C 3 133 ? 23.43062 0.50423   -5.16121  1.000 86.07481  ? 183 HIS E CB  1 
ATOM   4354 C CG  . HIS C 3 133 ? 23.45715 1.73284   -4.30584  1.000 99.04193  ? 183 HIS E CG  1 
ATOM   4355 N ND1 . HIS C 3 133 ? 23.40747 1.68251   -2.92938  1.000 96.93838  ? 183 HIS E ND1 1 
ATOM   4356 C CD2 . HIS C 3 133 ? 23.53255 3.04509   -4.63136  1.000 103.95038 ? 183 HIS E CD2 1 
ATOM   4357 C CE1 . HIS C 3 133 ? 23.44858 2.91054   -2.44404  1.000 93.76803  ? 183 HIS E CE1 1 
ATOM   4358 N NE2 . HIS C 3 133 ? 23.52442 3.75604   -3.45591  1.000 93.50352  ? 183 HIS E NE2 1 
ATOM   4359 N N   . HIS C 3 134 ? 26.25916 2.00301   -5.97017  1.000 89.61209  ? 184 HIS E N   1 
ATOM   4360 C CA  . HIS C 3 134 ? 27.57864 2.36811   -5.45445  1.000 102.18652 ? 184 HIS E CA  1 
ATOM   4361 C C   . HIS C 3 134 ? 27.38813 3.34766   -4.30597  1.000 106.87412 ? 184 HIS E C   1 
ATOM   4362 O O   . HIS C 3 134 ? 27.21620 4.55753   -4.54082  1.000 117.71275 ? 184 HIS E O   1 
ATOM   4363 C CB  . HIS C 3 134 ? 28.44971 2.98143   -6.54966  1.000 109.73472 ? 184 HIS E CB  1 
ATOM   4364 C CG  . HIS C 3 134 ? 28.80244 2.02730   -7.64846  1.000 111.31994 ? 184 HIS E CG  1 
ATOM   4365 N ND1 . HIS C 3 134 ? 30.08847 1.57883   -7.86024  1.000 102.46240 ? 184 HIS E ND1 1 
ATOM   4366 C CD2 . HIS C 3 134 ? 28.03811 1.43992   -8.59953  1.000 106.26342 ? 184 HIS E CD2 1 
ATOM   4367 C CE1 . HIS C 3 134 ? 30.10084 0.75448   -8.89248  1.000 110.51183 ? 184 HIS E CE1 1 
ATOM   4368 N NE2 . HIS C 3 134 ? 28.86940 0.65315   -9.35934  1.000 111.01367 ? 184 HIS E NE2 1 
ATOM   4369 N N   . PRO C 3 135 ? 27.39503 2.88100   -3.05728  1.000 97.00350  ? 185 PRO E N   1 
ATOM   4370 C CA  . PRO C 3 135 ? 27.14020 3.78396   -1.92912  1.000 101.35978 ? 185 PRO E CA  1 
ATOM   4371 C C   . PRO C 3 135 ? 28.21135 4.85697   -1.80261  1.000 101.19457 ? 185 PRO E C   1 
ATOM   4372 O O   . PRO C 3 135 ? 29.38660 4.63691   -2.10410  1.000 95.34589  ? 185 PRO E O   1 
ATOM   4373 C CB  . PRO C 3 135 ? 27.14556 2.84262   -0.71790  1.000 111.80342 ? 185 PRO E CB  1 
ATOM   4374 C CG  . PRO C 3 135 ? 26.82502 1.49490   -1.29825  1.000 95.40998  ? 185 PRO E CG  1 
ATOM   4375 C CD  . PRO C 3 135 ? 27.54802 1.48756   -2.61062  1.000 99.76438  ? 185 PRO E CD  1 
ATOM   4376 N N   . SER C 3 136 ? 27.78368 6.03671   -1.34668  1.000 94.35376  ? 186 SER E N   1 
ATOM   4377 C CA  . SER C 3 136 ? 28.71608 7.14561   -1.17275  1.000 100.82806 ? 186 SER E CA  1 
ATOM   4378 C C   . SER C 3 136 ? 29.59586 6.94601   0.05603   1.000 112.97212 ? 186 SER E C   1 
ATOM   4379 O O   . SER C 3 136 ? 30.77678 7.31263   0.04548   1.000 114.01452 ? 186 SER E O   1 
ATOM   4380 C CB  . SER C 3 136 ? 27.94976 8.46515   -1.07967  1.000 99.75714  ? 186 SER E CB  1 
ATOM   4381 O OG  . SER C 3 136 ? 26.90265 8.38366   -0.12878  1.000 102.69174 ? 186 SER E OG  1 
ATOM   4382 N N   . ASN C 3 137 ? 29.04381 6.36934   1.12239   1.000 100.10033 ? 187 ASN E N   1 
ATOM   4383 C CA  . ASN C 3 137 ? 29.78346 6.14226   2.35467   1.000 106.98779 ? 187 ASN E CA  1 
ATOM   4384 C C   . ASN C 3 137 ? 29.68090 4.67724   2.75346   1.000 106.76976 ? 187 ASN E C   1 
ATOM   4385 O O   . ASN C 3 137 ? 28.70460 3.99446   2.43133   1.000 105.27452 ? 187 ASN E O   1 
ATOM   4386 C CB  . ASN C 3 137 ? 29.27146 7.03394   3.49685   1.000 116.94987 ? 187 ASN E CB  1 
ATOM   4387 C CG  . ASN C 3 137 ? 27.82629 6.75309   3.85418   1.000 112.40798 ? 187 ASN E CG  1 
ATOM   4388 O OD1 . ASN C 3 137 ? 27.54156 5.97584   4.76497   1.000 108.84145 ? 187 ASN E OD1 1 
ATOM   4389 N ND2 . ASN C 3 137 ? 26.90433 7.38529   3.13734   1.000 104.21434 ? 187 ASN E ND2 1 
ATOM   4390 N N   . ILE C 3 138 ? 30.70841 4.20178   3.46139   1.000 101.25355 ? 188 ILE E N   1 
ATOM   4391 C CA  . ILE C 3 138 ? 30.76531 2.79484   3.84595   1.000 100.15447 ? 188 ILE E CA  1 
ATOM   4392 C C   . ILE C 3 138 ? 29.68296 2.45574   4.86592   1.000 103.11362 ? 188 ILE E C   1 
ATOM   4393 O O   . ILE C 3 138 ? 29.15596 1.33605   4.87017   1.000 101.97678 ? 188 ILE E O   1 
ATOM   4394 C CB  . ILE C 3 138 ? 32.17484 2.44473   4.36389   1.000 98.48539  ? 188 ILE E CB  1 
ATOM   4395 C CG1 . ILE C 3 138 ? 32.29806 0.94079   4.62339   1.000 113.63544 ? 188 ILE E CG1 1 
ATOM   4396 C CG2 . ILE C 3 138 ? 32.52018 3.25413   5.60786   1.000 105.34949 ? 188 ILE E CG2 1 
ATOM   4397 C CD1 . ILE C 3 138 ? 33.71793 0.47563   4.86001   1.000 128.37790 ? 188 ILE E CD1 1 
ATOM   4398 N N   . GLU C 3 139 ? 29.33208 3.40090   5.74222   1.000 108.29820 ? 189 GLU E N   1 
ATOM   4399 C CA  . GLU C 3 139 ? 28.32989 3.12400   6.76755   1.000 112.11932 ? 189 GLU E CA  1 
ATOM   4400 C C   . GLU C 3 139 ? 26.96137 2.85458   6.15256   1.000 101.88821 ? 189 GLU E C   1 
ATOM   4401 O O   . GLU C 3 139 ? 26.22437 1.97889   6.62145   1.000 93.89340  ? 189 GLU E O   1 
ATOM   4402 C CB  . GLU C 3 139 ? 28.25916 4.28522   7.75816   1.000 116.72712 ? 189 GLU E CB  1 
ATOM   4403 C CG  . GLU C 3 139 ? 28.97905 4.01844   9.07005   1.000 114.94555 ? 189 GLU E CG  1 
ATOM   4404 C CD  . GLU C 3 139 ? 30.47628 3.85913   8.89914   1.000 116.70452 ? 189 GLU E CD  1 
ATOM   4405 O OE1 . GLU C 3 139 ? 31.08748 4.68749   8.19253   1.000 125.85892 ? 189 GLU E OE1 1 
ATOM   4406 O OE2 . GLU C 3 139 ? 31.04189 2.90354   9.47160   1.000 103.58941 ? 189 GLU E OE2 1 
ATOM   4407 N N   . ASP C 3 140 ? 26.59930 3.60203   5.10622   1.000 107.38180 ? 190 ASP E N   1 
ATOM   4408 C CA  . ASP C 3 140 ? 25.33414 3.34781   4.42432   1.000 100.79996 ? 190 ASP E CA  1 
ATOM   4409 C C   . ASP C 3 140 ? 25.32724 1.98097   3.75455   1.000 95.66429  ? 190 ASP E C   1 
ATOM   4410 O O   . ASP C 3 140 ? 24.27543 1.33739   3.66755   1.000 89.85657  ? 190 ASP E O   1 
ATOM   4411 C CB  . ASP C 3 140 ? 25.05743 4.44474   3.39620   1.000 101.94954 ? 190 ASP E CB  1 
ATOM   4412 C CG  . ASP C 3 140 ? 24.34406 5.63957   3.99738   1.000 114.20150 ? 190 ASP E CG  1 
ATOM   4413 O OD1 . ASP C 3 140 ? 23.89079 5.54163   5.15724   1.000 113.68748 ? 190 ASP E OD1 1 
ATOM   4414 O OD2 . ASP C 3 140 ? 24.23870 6.67773   3.31099   1.000 121.35813 ? 190 ASP E OD2 1 
ATOM   4415 N N   . GLN C 3 141 ? 26.48494 1.52576   3.27084   1.000 85.77074  ? 191 GLN E N   1 
ATOM   4416 C CA  . GLN C 3 141 ? 26.57015 0.19150   2.68736   1.000 80.50117  ? 191 GLN E CA  1 
ATOM   4417 C C   . GLN C 3 141 ? 26.26528 -0.88334  3.72438   1.000 80.67097  ? 191 GLN E C   1 
ATOM   4418 O O   . GLN C 3 141 ? 25.56010 -1.85698  3.43346   1.000 80.28773  ? 191 GLN E O   1 
ATOM   4419 C CB  . GLN C 3 141 ? 27.95593 -0.01969  2.07667   1.000 77.27333  ? 191 GLN E CB  1 
ATOM   4420 C CG  . GLN C 3 141 ? 28.32414 -1.47310  1.84832   1.000 83.95303  ? 191 GLN E CG  1 
ATOM   4421 C CD  . GLN C 3 141 ? 27.91270 -1.97235  0.47755   1.000 89.15839  ? 191 GLN E CD  1 
ATOM   4422 O OE1 . GLN C 3 141 ? 28.16968 -1.32266  -0.53518  1.000 84.81141  ? 191 GLN E OE1 1 
ATOM   4423 N NE2 . GLN C 3 141 ? 27.26712 -3.13241  0.43937   1.000 92.85928  ? 191 GLN E NE2 1 
ATOM   4424 N N   . ARG C 3 142 ? 26.78341 -0.72056  4.94391   1.000 88.37638  ? 192 ARG E N   1 
ATOM   4425 C CA  . ARG C 3 142 ? 26.52832 -1.70085  5.99469   1.000 84.21594  ? 192 ARG E CA  1 
ATOM   4426 C C   . ARG C 3 142 ? 25.07145 -1.67141  6.44223   1.000 77.58977  ? 192 ARG E C   1 
ATOM   4427 O O   . ARG C 3 142 ? 24.49850 -2.71411  6.77851   1.000 80.04034  ? 192 ARG E O   1 
ATOM   4428 C CB  . ARG C 3 142 ? 27.45631 -1.44793  7.18273   1.000 88.45792  ? 192 ARG E CB  1 
ATOM   4429 C CG  . ARG C 3 142 ? 28.54072 -2.49686  7.36702   1.000 95.62514  ? 192 ARG E CG  1 
ATOM   4430 C CD  . ARG C 3 142 ? 29.52605 -2.08247  8.44986   1.000 127.50800 ? 192 ARG E CD  1 
ATOM   4431 N NE  . ARG C 3 142 ? 30.26320 -0.87655  8.09117   1.000 129.42382 ? 192 ARG E NE  1 
ATOM   4432 C CZ  . ARG C 3 142 ? 31.32691 -0.42716  8.74317   1.000 129.99910 ? 192 ARG E CZ  1 
ATOM   4433 N NH1 . ARG C 3 142 ? 31.80917 -1.06126  9.79943   1.000 127.18870 ? 192 ARG E NH1 1 
ATOM   4434 N NH2 . ARG C 3 142 ? 31.92099 0.68718   8.32576   1.000 126.50593 ? 192 ARG E NH2 1 
ATOM   4435 N N   . ALA C 3 143 ? 24.45983 -0.48534  6.46574   1.000 67.54878  ? 193 ALA E N   1 
ATOM   4436 C CA  . ALA C 3 143 ? 23.08837 -0.36907  6.95155   1.000 77.16533  ? 193 ALA E CA  1 
ATOM   4437 C C   . ALA C 3 143 ? 22.10093 -1.07042  6.02611   1.000 88.22209  ? 193 ALA E C   1 
ATOM   4438 O O   . ALA C 3 143 ? 21.18409 -1.75580  6.49399   1.000 80.00693  ? 193 ALA E O   1 
ATOM   4439 C CB  . ALA C 3 143 ? 22.71430 1.10351   7.11605   1.000 82.99521  ? 193 ALA E CB  1 
ATOM   4440 N N   . ILE C 3 144 ? 22.27082 -0.91648  4.71500   1.000 91.93495  ? 194 ILE E N   1 
ATOM   4441 C CA  . ILE C 3 144 ? 21.28270 -1.42707  3.77158   1.000 82.03496  ? 194 ILE E CA  1 
ATOM   4442 C C   . ILE C 3 144 ? 21.59033 -2.85014  3.30998   1.000 77.30207  ? 194 ILE E C   1 
ATOM   4443 O O   . ILE C 3 144 ? 20.66507 -3.62945  3.06139   1.000 80.13054  ? 194 ILE E O   1 
ATOM   4444 C CB  . ILE C 3 144 ? 21.16198 -0.47696  2.56759   1.000 81.81028  ? 194 ILE E CB  1 
ATOM   4445 C CG1 . ILE C 3 144 ? 21.19136 0.98054   3.03110   1.000 80.98010  ? 194 ILE E CG1 1 
ATOM   4446 C CG2 . ILE C 3 144 ? 19.88834 -0.76208  1.78515   1.000 92.71099  ? 194 ILE E CG2 1 
ATOM   4447 C CD1 . ILE C 3 144 ? 21.31399 1.97800   1.90013   1.000 76.42170  ? 194 ILE E CD1 1 
ATOM   4448 N N   . TYR C 3 145 ? 22.86670 -3.21381  3.18771   1.000 74.17151  ? 195 TYR E N   1 
ATOM   4449 C CA  . TYR C 3 145 ? 23.24047 -4.49885  2.61722   1.000 77.33800  ? 195 TYR E CA  1 
ATOM   4450 C C   . TYR C 3 145 ? 23.99988 -5.40916  3.57057   1.000 72.56071  ? 195 TYR E C   1 
ATOM   4451 O O   . TYR C 3 145 ? 24.15114 -6.59778  3.26497   1.000 83.87831  ? 195 TYR E O   1 
ATOM   4452 C CB  . TYR C 3 145 ? 24.07648 -4.28877  1.34490   1.000 80.47218  ? 195 TYR E CB  1 
ATOM   4453 C CG  . TYR C 3 145 ? 23.48603 -3.25518  0.41262   1.000 64.69287  ? 195 TYR E CG  1 
ATOM   4454 C CD1 . TYR C 3 145 ? 22.27830 -3.48587  -0.23181  1.000 56.97887  ? 195 TYR E CD1 1 
ATOM   4455 C CD2 . TYR C 3 145 ? 24.12868 -2.04495  0.18651   1.000 63.60311  ? 195 TYR E CD2 1 
ATOM   4456 C CE1 . TYR C 3 145 ? 21.73030 -2.54459  -1.08098  1.000 76.32969  ? 195 TYR E CE1 1 
ATOM   4457 C CE2 . TYR C 3 145 ? 23.58886 -1.09730  -0.66248  1.000 71.44230  ? 195 TYR E CE2 1 
ATOM   4458 C CZ  . TYR C 3 145 ? 22.38924 -1.35247  -1.29297  1.000 75.94688  ? 195 TYR E CZ  1 
ATOM   4459 O OH  . TYR C 3 145 ? 21.84590 -0.41287  -2.13874  1.000 82.93709  ? 195 TYR E OH  1 
ATOM   4460 N N   . HIS C 3 146 ? 24.48638 -4.89354  4.69969   1.000 82.83211  ? 196 HIS E N   1 
ATOM   4461 C CA  . HIS C 3 146 ? 25.13290 -5.68544  5.74599   1.000 78.14224  ? 196 HIS E CA  1 
ATOM   4462 C C   . HIS C 3 146 ? 26.37444 -6.41912  5.24827   1.000 83.90787  ? 196 HIS E C   1 
ATOM   4463 O O   . HIS C 3 146 ? 26.79222 -7.41378  5.85008   1.000 91.28793  ? 196 HIS E O   1 
ATOM   4464 C CB  . HIS C 3 146 ? 24.15203 -6.68333  6.37358   1.000 57.96980  ? 196 HIS E CB  1 
ATOM   4465 C CG  . HIS C 3 146 ? 23.16381 -6.05452  7.30505   1.000 63.27179  ? 196 HIS E CG  1 
ATOM   4466 N ND1 . HIS C 3 146 ? 23.53721 -5.42104  8.47077   1.000 92.62459  ? 196 HIS E ND1 1 
ATOM   4467 C CD2 . HIS C 3 146 ? 21.81430 -5.96466  7.24395   1.000 65.45701  ? 196 HIS E CD2 1 
ATOM   4468 C CE1 . HIS C 3 146 ? 22.46053 -4.96603  9.08648   1.000 85.38396  ? 196 HIS E CE1 1 
ATOM   4469 N NE2 . HIS C 3 146 ? 21.40188 -5.28288  8.36295   1.000 74.93114  ? 196 HIS E NE2 1 
ATOM   4470 N N   . THR C 3 147 ? 26.97709 -5.95273  4.15715   1.000 77.15648  ? 197 THR E N   1 
ATOM   4471 C CA  . THR C 3 147 ? 28.19108 -6.56386  3.63742   1.000 83.74613  ? 197 THR E CA  1 
ATOM   4472 C C   . THR C 3 147 ? 29.05826 -5.48709  3.00325   1.000 82.10480  ? 197 THR E C   1 
ATOM   4473 O O   . THR C 3 147 ? 28.54766 -4.56848  2.35759   1.000 75.49716  ? 197 THR E O   1 
ATOM   4474 C CB  . THR C 3 147 ? 27.87915 -7.66931  2.61847   1.000 89.02018  ? 197 THR E CB  1 
ATOM   4475 O OG1 . THR C 3 147 ? 29.10049 -8.15672  2.04857   1.000 86.67477  ? 197 THR E OG1 1 
ATOM   4476 C CG2 . THR C 3 147 ? 26.97234 -7.15017  1.51013   1.000 80.60704  ? 197 THR E CG2 1 
ATOM   4477 N N   . GLU C 3 148 ? 30.37061 -5.60289  3.20136   1.000 89.19227  ? 198 GLU E N   1 
ATOM   4478 C CA  . GLU C 3 148 ? 31.31524 -4.65211  2.62895   1.000 93.75580  ? 198 GLU E CA  1 
ATOM   4479 C C   . GLU C 3 148 ? 31.84905 -5.11806  1.28015   1.000 109.70309 ? 198 GLU E C   1 
ATOM   4480 O O   . GLU C 3 148 ? 32.00893 -4.30537  0.36262   1.000 118.52089 ? 198 GLU E O   1 
ATOM   4481 C CB  . GLU C 3 148 ? 32.47408 -4.41388  3.60189   1.000 123.50932 ? 198 GLU E CB  1 
ATOM   4482 C CG  . GLU C 3 148 ? 33.64313 -3.64103  3.01148   1.000 140.29422 ? 198 GLU E CG  1 
ATOM   4483 C CD  . GLU C 3 148 ? 34.79965 -3.49994  3.98240   1.000 145.03722 ? 198 GLU E CD  1 
ATOM   4484 O OE1 . GLU C 3 148 ? 34.54907 -3.44626  5.20514   1.000 138.80164 ? 198 GLU E OE1 1 
ATOM   4485 O OE2 . GLU C 3 148 ? 35.95959 -3.44254  3.52234   1.000 134.98419 ? 198 GLU E OE2 1 
ATOM   4486 N N   . ASN C 3 149 ? 32.11963 -6.41540  1.13923   1.000 109.53071 ? 199 ASN E N   1 
ATOM   4487 C CA  . ASN C 3 149 ? 32.59624 -6.97846  -0.12459  1.000 118.41138 ? 199 ASN E CA  1 
ATOM   4488 C C   . ASN C 3 149 ? 31.39622 -7.41427  -0.96685  1.000 112.57582 ? 199 ASN E C   1 
ATOM   4489 O O   . ASN C 3 149 ? 31.12655 -8.59832  -1.17787  1.000 102.59622 ? 199 ASN E O   1 
ATOM   4490 C CB  . ASN C 3 149 ? 33.55385 -8.13367  0.13650   1.000 123.14676 ? 199 ASN E CB  1 
ATOM   4491 C CG  . ASN C 3 149 ? 34.60319 -7.79535  1.17678   1.000 139.46580 ? 199 ASN E CG  1 
ATOM   4492 O OD1 . ASN C 3 149 ? 35.00295 -6.63953  1.31855   1.000 139.74175 ? 199 ASN E OD1 1 
ATOM   4493 N ND2 . ASN C 3 149 ? 35.05347 -8.80448  1.91373   1.000 135.10465 ? 199 ASN E ND2 1 
ATOM   4494 N N   . ALA C 3 150 ? 30.66639 -6.41240  -1.44980  1.000 103.33759 ? 200 ALA E N   1 
ATOM   4495 C CA  . ALA C 3 150 ? 29.46474 -6.66885  -2.22993  1.000 85.62819  ? 200 ALA E CA  1 
ATOM   4496 C C   . ALA C 3 150 ? 29.82039 -7.19110  -3.61552  1.000 89.99277  ? 200 ALA E C   1 
ATOM   4497 O O   . ALA C 3 150 ? 30.78164 -6.73734  -4.24251  1.000 95.95504  ? 200 ALA E O   1 
ATOM   4498 C CB  . ALA C 3 150 ? 28.62691 -5.39695  -2.34837  1.000 78.27741  ? 200 ALA E CB  1 
ATOM   4499 N N   . TYR C 3 151 ? 29.03616 -8.15569  -4.09112  1.000 92.39846  ? 201 TYR E N   1 
ATOM   4500 C CA  . TYR C 3 151 ? 29.20933 -8.71426  -5.42295  1.000 91.12007  ? 201 TYR E CA  1 
ATOM   4501 C C   . TYR C 3 151 ? 27.84540 -8.88465  -6.07277  1.000 92.27163  ? 201 TYR E C   1 
ATOM   4502 O O   . TYR C 3 151 ? 26.87608 -9.25903  -5.40776  1.000 87.19362  ? 201 TYR E O   1 
ATOM   4503 C CB  . TYR C 3 151 ? 29.95550 -10.05873 -5.37626  1.000 91.39801  ? 201 TYR E CB  1 
ATOM   4504 C CG  . TYR C 3 151 ? 29.08022 -11.25924 -5.07750  1.000 94.42413  ? 201 TYR E CG  1 
ATOM   4505 C CD1 . TYR C 3 151 ? 28.83609 -11.65387 -3.76948  1.000 100.25923 ? 201 TYR E CD1 1 
ATOM   4506 C CD2 . TYR C 3 151 ? 28.51657 -12.01074 -6.10348  1.000 106.95111 ? 201 TYR E CD2 1 
ATOM   4507 C CE1 . TYR C 3 151 ? 28.04164 -12.75015 -3.48877  1.000 109.82570 ? 201 TYR E CE1 1 
ATOM   4508 C CE2 . TYR C 3 151 ? 27.72028 -13.10809 -5.83221  1.000 109.83321 ? 201 TYR E CE2 1 
ATOM   4509 C CZ  . TYR C 3 151 ? 27.48764 -13.47370 -4.52310  1.000 102.69350 ? 201 TYR E CZ  1 
ATOM   4510 O OH  . TYR C 3 151 ? 26.69859 -14.56629 -4.24603  1.000 104.77202 ? 201 TYR E OH  1 
ATOM   4511 N N   . VAL C 3 152 ? 27.77383 -8.59282  -7.36932  1.000 88.14276  ? 202 VAL E N   1 
ATOM   4512 C CA  . VAL C 3 152 ? 26.58065 -8.82816  -8.17503  1.000 79.68740  ? 202 VAL E CA  1 
ATOM   4513 C C   . VAL C 3 152 ? 27.01564 -9.56205  -9.43429  1.000 83.90611  ? 202 VAL E C   1 
ATOM   4514 O O   . VAL C 3 152 ? 27.88933 -9.07997  -10.16531 1.000 90.01765  ? 202 VAL E O   1 
ATOM   4515 C CB  . VAL C 3 152 ? 25.85001 -7.52324  -8.53430  1.000 89.13321  ? 202 VAL E CB  1 
ATOM   4516 C CG1 . VAL C 3 152 ? 24.63314 -7.81972  -9.39851  1.000 65.29334  ? 202 VAL E CG1 1 
ATOM   4517 C CG2 . VAL C 3 152 ? 25.44261 -6.77308  -7.27435  1.000 76.36174  ? 202 VAL E CG2 1 
ATOM   4518 N N   . SER C 3 153 ? 26.41145 -10.71997 -9.68925  1.000 84.37907  ? 203 SER E N   1 
ATOM   4519 C CA  . SER C 3 153 ? 26.77115 -11.56059 -10.82445 1.000 76.10093  ? 203 SER E CA  1 
ATOM   4520 C C   . SER C 3 153 ? 25.54764 -11.76693 -11.70418 1.000 75.79176  ? 203 SER E C   1 
ATOM   4521 O O   . SER C 3 153 ? 24.52321 -12.27822 -11.23914 1.000 71.99435  ? 203 SER E O   1 
ATOM   4522 C CB  . SER C 3 153 ? 27.32840 -12.90625 -10.35580 1.000 82.10607  ? 203 SER E CB  1 
ATOM   4523 O OG  . SER C 3 153 ? 27.90421 -13.62224 -11.43420 1.000 82.58281  ? 203 SER E OG  1 
ATOM   4524 N N   . VAL C 3 154 ? 25.65748 -11.37013 -12.96894 1.000 81.86970  ? 204 VAL E N   1 
ATOM   4525 C CA  . VAL C 3 154 ? 24.62634 -11.60263 -13.97365 1.000 74.95260  ? 204 VAL E CA  1 
ATOM   4526 C C   . VAL C 3 154 ? 25.24693 -12.48710 -15.04524 1.000 73.21050  ? 204 VAL E C   1 
ATOM   4527 O O   . VAL C 3 154 ? 26.15311 -12.05367 -15.76872 1.000 83.84532  ? 204 VAL E O   1 
ATOM   4528 C CB  . VAL C 3 154 ? 24.09559 -10.29365 -14.57276 1.000 71.53307  ? 204 VAL E CB  1 
ATOM   4529 C CG1 . VAL C 3 154 ? 22.91166 -10.57030 -15.48130 1.000 82.08367  ? 204 VAL E CG1 1 
ATOM   4530 C CG2 . VAL C 3 154 ? 23.70808 -9.32288  -13.46848 1.000 79.74224  ? 204 VAL E CG2 1 
ATOM   4531 N N   . VAL C 3 155 ? 24.76540 -13.72340 -15.15106 1.000 71.85551  ? 205 VAL E N   1 
ATOM   4532 C CA  . VAL C 3 155 ? 25.34939 -14.72241 -16.03778 1.000 81.98833  ? 205 VAL E CA  1 
ATOM   4533 C C   . VAL C 3 155 ? 24.24821 -15.32316 -16.89932 1.000 79.99777  ? 205 VAL E C   1 
ATOM   4534 O O   . VAL C 3 155 ? 23.19605 -15.71881 -16.38507 1.000 69.72068  ? 205 VAL E O   1 
ATOM   4535 C CB  . VAL C 3 155 ? 26.08044 -15.82740 -15.24995 1.000 84.96280  ? 205 VAL E CB  1 
ATOM   4536 C CG1 . VAL C 3 155 ? 26.58736 -16.90850 -16.19166 1.000 54.73081  ? 205 VAL E CG1 1 
ATOM   4537 C CG2 . VAL C 3 155 ? 27.22850 -15.23699 -14.44309 1.000 98.40893  ? 205 VAL E CG2 1 
ATOM   4538 N N   . SER C 3 156 ? 24.49134 -15.38539 -18.20778 1.000 89.88278  ? 206 SER E N   1 
ATOM   4539 C CA  . SER C 3 156 ? 23.61172 -16.06291 -19.14851 1.000 75.86658  ? 206 SER E CA  1 
ATOM   4540 C C   . SER C 3 156 ? 24.47444 -16.71555 -20.22042 1.000 75.24068  ? 206 SER E C   1 
ATOM   4541 O O   . SER C 3 156 ? 25.70511 -16.61004 -20.20529 1.000 78.53964  ? 206 SER E O   1 
ATOM   4542 C CB  . SER C 3 156 ? 22.59414 -15.09515 -19.76359 1.000 61.06687  ? 206 SER E CB  1 
ATOM   4543 O OG  . SER C 3 156 ? 23.20558 -14.26414 -20.73345 1.000 57.98950  ? 206 SER E OG  1 
ATOM   4544 N N   . SER C 3 157 ? 23.81993 -17.40418 -21.15794 1.000 82.72982  ? 207 SER E N   1 
ATOM   4545 C CA  . SER C 3 157 ? 24.55349 -18.05506 -22.23912 1.000 76.37893  ? 207 SER E CA  1 
ATOM   4546 C C   . SER C 3 157 ? 25.23976 -17.03480 -23.13912 1.000 77.29722  ? 207 SER E C   1 
ATOM   4547 O O   . SER C 3 157 ? 26.37486 -17.25160 -23.57931 1.000 73.48445  ? 207 SER E O   1 
ATOM   4548 C CB  . SER C 3 157 ? 23.61293 -18.94174 -23.05301 1.000 64.41392  ? 207 SER E CB  1 
ATOM   4549 O OG  . SER C 3 157 ? 23.03393 -19.94662 -22.24023 1.000 74.85006  ? 207 SER E OG  1 
ATOM   4550 N N   . HIS C 3 158 ? 24.57002 -15.91911 -23.42354 1.000 76.48359  ? 208 HIS E N   1 
ATOM   4551 C CA  . HIS C 3 158 ? 25.11122 -14.89631 -24.30904 1.000 75.54067  ? 208 HIS E CA  1 
ATOM   4552 C C   . HIS C 3 158 ? 25.81761 -13.76825 -23.57255 1.000 63.67151  ? 208 HIS E C   1 
ATOM   4553 O O   . HIS C 3 158 ? 26.80250 -13.23066 -24.08854 1.000 69.35926  ? 208 HIS E O   1 
ATOM   4554 C CB  . HIS C 3 158 ? 23.99457 -14.30634 -25.17686 1.000 90.65123  ? 208 HIS E CB  1 
ATOM   4555 C CG  . HIS C 3 158 ? 23.35488 -15.30188 -26.09344 1.000 99.23312  ? 208 HIS E CG  1 
ATOM   4556 N ND1 . HIS C 3 158 ? 22.38790 -16.18838 -25.67072 1.000 98.48954  ? 208 HIS E ND1 1 
ATOM   4557 C CD2 . HIS C 3 158 ? 23.54688 -15.55423 -27.40979 1.000 92.50847  ? 208 HIS E CD2 1 
ATOM   4558 C CE1 . HIS C 3 158 ? 22.00995 -16.94223 -26.68758 1.000 92.95378  ? 208 HIS E CE1 1 
ATOM   4559 N NE2 . HIS C 3 158 ? 22.69806 -16.57785 -27.75449 1.000 99.50407  ? 208 HIS E NE2 1 
ATOM   4560 N N   . TYR C 3 159 ? 25.34566 -13.39838 -22.38560 1.000 87.04519  ? 209 TYR E N   1 
ATOM   4561 C CA  . TYR C 3 159 ? 25.91539 -12.30425 -21.61323 1.000 86.63356  ? 209 TYR E CA  1 
ATOM   4562 C C   . TYR C 3 159 ? 26.38372 -12.82770 -20.26292 1.000 86.63559  ? 209 TYR E C   1 
ATOM   4563 O O   . TYR C 3 159 ? 25.70551 -13.64687 -19.63521 1.000 72.75265  ? 209 TYR E O   1 
ATOM   4564 C CB  . TYR C 3 159 ? 24.89095 -11.17553 -21.42696 1.000 75.98059  ? 209 TYR E CB  1 
ATOM   4565 C CG  . TYR C 3 159 ? 25.35420 -10.03522 -20.54512 1.000 99.00313  ? 209 TYR E CG  1 
ATOM   4566 C CD1 . TYR C 3 159 ? 26.03309 -8.94967  -21.08370 1.000 115.59324 ? 209 TYR E CD1 1 
ATOM   4567 C CD2 . TYR C 3 159 ? 25.09279 -10.03181 -19.17984 1.000 91.23597  ? 209 TYR E CD2 1 
ATOM   4568 C CE1 . TYR C 3 159 ? 26.45339 -7.90120  -20.28684 1.000 108.76074 ? 209 TYR E CE1 1 
ATOM   4569 C CE2 . TYR C 3 159 ? 25.50988 -8.98766  -18.37510 1.000 96.85880  ? 209 TYR E CE2 1 
ATOM   4570 C CZ  . TYR C 3 159 ? 26.18870 -7.92502  -18.93442 1.000 100.65537 ? 209 TYR E CZ  1 
ATOM   4571 O OH  . TYR C 3 159 ? 26.60521 -6.88187  -18.14012 1.000 107.66432 ? 209 TYR E OH  1 
ATOM   4572 N N   . SER C 3 160 ? 27.54752 -12.35541 -19.82143 1.000 96.06466  ? 210 SER E N   1 
ATOM   4573 C CA  . SER C 3 160 ? 28.11682 -12.78796 -18.54903 1.000 89.42591  ? 210 SER E CA  1 
ATOM   4574 C C   . SER C 3 160 ? 28.99904 -11.67692 -18.00398 1.000 74.80254  ? 210 SER E C   1 
ATOM   4575 O O   . SER C 3 160 ? 29.96732 -11.27750 -18.65742 1.000 93.33683  ? 210 SER E O   1 
ATOM   4576 C CB  . SER C 3 160 ? 28.91829 -14.08069 -18.71759 1.000 91.75594  ? 210 SER E CB  1 
ATOM   4577 O OG  . SER C 3 160 ? 29.57390 -14.43568 -17.51298 1.000 100.17931 ? 210 SER E OG  1 
ATOM   4578 N N   . ARG C 3 161 ? 28.66782 -11.18479 -16.81237 1.000 87.70759  ? 211 ARG E N   1 
ATOM   4579 C CA  . ARG C 3 161 ? 29.43468 -10.12281 -16.17819 1.000 104.10325 ? 211 ARG E CA  1 
ATOM   4580 C C   . ARG C 3 161 ? 29.25127 -10.20578 -14.67052 1.000 95.14652  ? 211 ARG E C   1 
ATOM   4581 O O   . ARG C 3 161 ? 28.16837 -10.54770 -14.18771 1.000 82.62219  ? 211 ARG E O   1 
ATOM   4582 C CB  . ARG C 3 161 ? 29.00749 -8.74101  -16.68837 1.000 92.92068  ? 211 ARG E CB  1 
ATOM   4583 C CG  . ARG C 3 161 ? 29.95839 -7.61584  -16.31065 1.000 88.08740  ? 211 ARG E CG  1 
ATOM   4584 C CD  . ARG C 3 161 ? 29.69317 -6.36649  -17.13456 1.000 112.05738 ? 211 ARG E CD  1 
ATOM   4585 N NE  . ARG C 3 161 ? 30.31886 -5.18525  -16.55186 1.000 115.41161 ? 211 ARG E NE  1 
ATOM   4586 C CZ  . ARG C 3 161 ? 30.22868 -3.96256  -17.05741 1.000 110.57850 ? 211 ARG E CZ  1 
ATOM   4587 N NH1 . ARG C 3 161 ? 29.54345 -3.72024  -18.16307 1.000 99.62955  ? 211 ARG E NH1 1 
ATOM   4588 N NH2 . ARG C 3 161 ? 30.84063 -2.95741  -16.43756 1.000 102.80101 ? 211 ARG E NH2 1 
ATOM   4589 N N   . ARG C 3 162 ? 30.31503 -9.88961  -13.93556 1.000 101.49903 ? 212 ARG E N   1 
ATOM   4590 C CA  . ARG C 3 162 ? 30.30107 -9.88025  -12.47797 1.000 99.12451  ? 212 ARG E CA  1 
ATOM   4591 C C   . ARG C 3 162 ? 30.70473 -8.49348  -11.99936 1.000 94.96855  ? 212 ARG E C   1 
ATOM   4592 O O   . ARG C 3 162 ? 31.78362 -8.00278  -12.34880 1.000 102.17106 ? 212 ARG E O   1 
ATOM   4593 C CB  . ARG C 3 162 ? 31.24256 -10.94593 -11.91269 1.000 90.31226  ? 212 ARG E CB  1 
ATOM   4594 C CG  . ARG C 3 162 ? 31.28663 -10.99668 -10.39535 1.000 123.27947 ? 212 ARG E CG  1 
ATOM   4595 C CD  . ARG C 3 162 ? 32.27865 -12.04046 -9.90795  1.000 143.26274 ? 212 ARG E CD  1 
ATOM   4596 N NE  . ARG C 3 162 ? 32.53493 -11.92483 -8.47727  1.000 120.30787 ? 212 ARG E NE  1 
ATOM   4597 C CZ  . ARG C 3 162 ? 31.87779 -12.59690 -7.54207  1.000 107.55209 ? 212 ARG E CZ  1 
ATOM   4598 N NH1 . ARG C 3 162 ? 30.91006 -13.44454 -7.85107  1.000 98.16922  ? 212 ARG E NH1 1 
ATOM   4599 N NH2 . ARG C 3 162 ? 32.20024 -12.41466 -6.26477  1.000 129.11287 ? 212 ARG E NH2 1 
ATOM   4600 N N   . PHE C 3 163 ? 29.84426 -7.86850  -11.20199 1.000 91.09019  ? 213 PHE E N   1 
ATOM   4601 C CA  . PHE C 3 163 ? 30.07152 -6.51786  -10.70892 1.000 97.65544  ? 213 PHE E CA  1 
ATOM   4602 C C   . PHE C 3 163 ? 30.50867 -6.55144  -9.25054  1.000 102.00153 ? 213 PHE E C   1 
ATOM   4603 O O   . PHE C 3 163 ? 29.93231 -7.27520  -8.43308  1.000 99.31090  ? 213 PHE E O   1 
ATOM   4604 C CB  . PHE C 3 163 ? 28.81250 -5.65694  -10.84950 1.000 84.26425  ? 213 PHE E CB  1 
ATOM   4605 C CG  . PHE C 3 163 ? 28.11002 -5.81072  -12.16961 1.000 88.82093  ? 213 PHE E CG  1 
ATOM   4606 C CD1 . PHE C 3 163 ? 27.14743 -6.79086  -12.35136 1.000 92.57144  ? 213 PHE E CD1 1 
ATOM   4607 C CD2 . PHE C 3 163 ? 28.41001 -4.96991  -13.22854 1.000 103.63687 ? 213 PHE E CD2 1 
ATOM   4608 C CE1 . PHE C 3 163 ? 26.50030 -6.93054  -13.56538 1.000 102.68452 ? 213 PHE E CE1 1 
ATOM   4609 C CE2 . PHE C 3 163 ? 27.76611 -5.10422  -14.44412 1.000 93.33869  ? 213 PHE E CE2 1 
ATOM   4610 C CZ  . PHE C 3 163 ? 26.81044 -6.08603  -14.61280 1.000 97.82015  ? 213 PHE E CZ  1 
ATOM   4611 N N   . THR C 3 164 ? 31.53356 -5.75951  -8.93130  1.000 102.36207 ? 214 THR E N   1 
ATOM   4612 C CA  . THR C 3 164 ? 32.02653 -5.59027  -7.56493  1.000 95.28587  ? 214 THR E CA  1 
ATOM   4613 C C   . THR C 3 164 ? 31.97871 -4.10279  -7.24396  1.000 99.92337  ? 214 THR E C   1 
ATOM   4614 O O   . THR C 3 164 ? 32.97823 -3.38753  -7.41968  1.000 105.11800 ? 214 THR E O   1 
ATOM   4615 C CB  . THR C 3 164 ? 33.44147 -6.14377  -7.40401  1.000 76.11211  ? 214 THR E CB  1 
ATOM   4616 O OG1 . THR C 3 164 ? 34.32506 -5.47739  -8.31448  1.000 100.12437 ? 214 THR E OG1 1 
ATOM   4617 C CG2 . THR C 3 164 ? 33.46545 -7.63917  -7.68274  1.000 70.46749  ? 214 THR E CG2 1 
ATOM   4618 N N   . PRO C 3 165 ? 30.83527 -3.59178  -6.78691  1.000 89.38937  ? 215 PRO E N   1 
ATOM   4619 C CA  . PRO C 3 165 ? 30.72458 -2.15335  -6.51909  1.000 87.10335  ? 215 PRO E CA  1 
ATOM   4620 C C   . PRO C 3 165 ? 31.68733 -1.70616  -5.42975  1.000 107.38580 ? 215 PRO E C   1 
ATOM   4621 O O   . PRO C 3 165 ? 31.97466 -2.43740  -4.47959  1.000 108.93455 ? 215 PRO E O   1 
ATOM   4622 C CB  . PRO C 3 165 ? 29.26448 -1.98077  -6.08151  1.000 89.80400  ? 215 PRO E CB  1 
ATOM   4623 C CG  . PRO C 3 165 ? 28.81482 -3.34333  -5.66769  1.000 100.82918 ? 215 PRO E CG  1 
ATOM   4624 C CD  . PRO C 3 165 ? 29.58228 -4.31253  -6.50848  1.000 93.07206  ? 215 PRO E CD  1 
ATOM   4625 N N   . GLU C 3 166 ? 32.18779 -0.48396  -5.58380  1.000 121.74675 ? 216 GLU E N   1 
ATOM   4626 C CA  . GLU C 3 166 ? 33.13682 0.11232   -4.65644  1.000 114.08301 ? 216 GLU E CA  1 
ATOM   4627 C C   . GLU C 3 166 ? 32.56423 1.41317   -4.11334  1.000 115.93625 ? 216 GLU E C   1 
ATOM   4628 O O   . GLU C 3 166 ? 31.96406 2.19600   -4.85674  1.000 129.88495 ? 216 GLU E O   1 
ATOM   4629 C CB  . GLU C 3 166 ? 34.48383 0.37361   -5.34060  1.000 132.37414 ? 216 GLU E CB  1 
ATOM   4630 C CG  . GLU C 3 166 ? 35.56685 0.90571   -4.41687  1.000 148.78765 ? 216 GLU E CG  1 
ATOM   4631 C CD  . GLU C 3 166 ? 36.85379 1.22290   -5.15391  1.000 172.42522 ? 216 GLU E CD  1 
ATOM   4632 O OE1 . GLU C 3 166 ? 36.87067 1.11163   -6.39814  1.000 171.01207 ? 216 GLU E OE1 1 
ATOM   4633 O OE2 . GLU C 3 166 ? 37.84769 1.58541   -4.48990  1.000 176.26933 ? 216 GLU E OE2 1 
ATOM   4634 N N   . ILE C 3 167 ? 32.74976 1.63923   -2.81671  1.000 120.14521 ? 217 ILE E N   1 
ATOM   4635 C CA  . ILE C 3 167 ? 32.24980 2.84893   -2.17222  1.000 118.64968 ? 217 ILE E CA  1 
ATOM   4636 C C   . ILE C 3 167 ? 33.19141 3.99989   -2.50278  1.000 114.42579 ? 217 ILE E C   1 
ATOM   4637 O O   . ILE C 3 167 ? 34.38893 3.94227   -2.20434  1.000 118.74364 ? 217 ILE E O   1 
ATOM   4638 C CB  . ILE C 3 167 ? 32.11985 2.65719   -0.65446  1.000 105.55405 ? 217 ILE E CB  1 
ATOM   4639 C CG1 . ILE C 3 167 ? 30.94270 1.73425   -0.32900  1.000 103.33043 ? 217 ILE E CG1 1 
ATOM   4640 C CG2 . ILE C 3 167 ? 31.95301 4.00011   0.04088   1.000 106.85660 ? 217 ILE E CG2 1 
ATOM   4641 C CD1 . ILE C 3 167 ? 31.32766 0.27856   -0.16583  1.000 119.55006 ? 217 ILE E CD1 1 
ATOM   4642 N N   . ALA C 3 168 ? 32.65164 5.04657   -3.12308  1.000 103.33679 ? 218 ALA E N   1 
ATOM   4643 C CA  . ALA C 3 168 ? 33.44783 6.20625   -3.50966  1.000 108.15999 ? 218 ALA E CA  1 
ATOM   4644 C C   . ALA C 3 168 ? 32.54895 7.43109   -3.52395  1.000 119.35080 ? 218 ALA E C   1 
ATOM   4645 O O   . ALA C 3 168 ? 31.56824 7.47047   -4.27325  1.000 106.82258 ? 218 ALA E O   1 
ATOM   4646 C CB  . ALA C 3 168 ? 34.09839 5.99787   -4.87881  1.000 96.36205  ? 218 ALA E CB  1 
ATOM   4647 N N   . LYS C 3 169 ? 32.87985 8.42090   -2.69810  1.000 126.49134 ? 219 LYS E N   1 
ATOM   4648 C CA  . LYS C 3 169 ? 32.11108 9.65716   -2.66651  1.000 114.48301 ? 219 LYS E CA  1 
ATOM   4649 C C   . LYS C 3 169 ? 32.32063 10.43233  -3.96137  1.000 122.59125 ? 219 LYS E C   1 
ATOM   4650 O O   . LYS C 3 169 ? 33.45364 10.59652  -4.42428  1.000 124.77680 ? 219 LYS E O   1 
ATOM   4651 C CB  . LYS C 3 169 ? 32.51725 10.50391  -1.46175  1.000 112.61117 ? 219 LYS E CB  1 
ATOM   4652 C CG  . LYS C 3 169 ? 31.51523 11.58713  -1.09707  1.000 129.23786 ? 219 LYS E CG  1 
ATOM   4653 C CD  . LYS C 3 169 ? 31.67324 12.01690  0.35342   1.000 127.28726 ? 219 LYS E CD  1 
ATOM   4654 C CE  . LYS C 3 169 ? 31.43707 10.85115  1.30169   1.000 127.54239 ? 219 LYS E CE  1 
ATOM   4655 N NZ  . LYS C 3 169 ? 31.66173 11.23131  2.72364   1.000 136.81913 ? 219 LYS E NZ  1 
ATOM   4656 N N   . ARG C 3 170 ? 31.22941 10.90869  -4.54154  1.000 116.03663 ? 220 ARG E N   1 
ATOM   4657 C CA  . ARG C 3 170 ? 31.22614 11.57217  -5.83428  1.000 121.74570 ? 220 ARG E CA  1 
ATOM   4658 C C   . ARG C 3 170 ? 30.48983 12.89650  -5.72376  1.000 124.56808 ? 220 ARG E C   1 
ATOM   4659 O O   . ARG C 3 170 ? 29.70917 13.10383  -4.78807  1.000 131.39206 ? 220 ARG E O   1 
ATOM   4660 C CB  . ARG C 3 170 ? 30.56657 10.68584  -6.90232  1.000 117.23826 ? 220 ARG E CB  1 
ATOM   4661 C CG  . ARG C 3 170 ? 31.52983 9.72097   -7.57456  1.000 109.41329 ? 220 ARG E CG  1 
ATOM   4662 C CD  . ARG C 3 170 ? 30.92525 9.10919   -8.82567  1.000 98.34946  ? 220 ARG E CD  1 
ATOM   4663 N NE  . ARG C 3 170 ? 31.92469 8.41338   -9.62709  1.000 110.15973 ? 220 ARG E NE  1 
ATOM   4664 C CZ  . ARG C 3 170 ? 32.60833 8.96790   -10.61877 1.000 122.05642 ? 220 ARG E CZ  1 
ATOM   4665 N NH1 . ARG C 3 170 ? 32.42366 10.23178  -10.96384 1.000 121.79400 ? 220 ARG E NH1 1 
ATOM   4666 N NH2 . ARG C 3 170 ? 33.49988 8.23604   -11.28087 1.000 119.86108 ? 220 ARG E NH2 1 
ATOM   4667 N N   . PRO C 3 171 ? 30.73360 13.82584  -6.65144  1.000 116.72019 ? 221 PRO E N   1 
ATOM   4668 C CA  . PRO C 3 171 ? 30.03838 15.11827  -6.59773  1.000 121.19664 ? 221 PRO E CA  1 
ATOM   4669 C C   . PRO C 3 171 ? 28.52670 14.94575  -6.62886  1.000 111.09387 ? 221 PRO E C   1 
ATOM   4670 O O   . PRO C 3 171 ? 27.99427 14.06586  -7.30873  1.000 118.61818 ? 221 PRO E O   1 
ATOM   4671 C CB  . PRO C 3 171 ? 30.54896 15.84525  -7.84618  1.000 127.93796 ? 221 PRO E CB  1 
ATOM   4672 C CG  . PRO C 3 171 ? 31.88906 15.24685  -8.09551  1.000 122.89293 ? 221 PRO E CG  1 
ATOM   4673 C CD  . PRO C 3 171 ? 31.76266 13.80131  -7.70706  1.000 111.94085 ? 221 PRO E CD  1 
ATOM   4674 N N   . LYS C 3 172 ? 27.83943 15.80152  -5.87588  1.000 104.13621 ? 222 LYS E N   1 
ATOM   4675 C CA  . LYS C 3 172 ? 26.39985 15.67136  -5.68868  1.000 117.04990 ? 222 LYS E CA  1 
ATOM   4676 C C   . LYS C 3 172 ? 25.66576 15.93176  -6.99822  1.000 116.26802 ? 222 LYS E C   1 
ATOM   4677 O O   . LYS C 3 172 ? 25.76088 17.02399  -7.56799  1.000 123.77307 ? 222 LYS E O   1 
ATOM   4678 C CB  . LYS C 3 172 ? 25.92388 16.63812  -4.60737  1.000 146.56914 ? 222 LYS E CB  1 
ATOM   4679 C CG  . LYS C 3 172 ? 24.73160 16.14181  -3.80603  1.000 142.61984 ? 222 LYS E CG  1 
ATOM   4680 C CD  . LYS C 3 172 ? 24.32329 17.15214  -2.74551  1.000 139.37494 ? 222 LYS E CD  1 
ATOM   4681 C CE  . LYS C 3 172 ? 23.96992 18.49326  -3.36951  1.000 156.57080 ? 222 LYS E CE  1 
ATOM   4682 N NZ  . LYS C 3 172 ? 23.50237 19.47672  -2.35385  1.000 144.64067 ? 222 LYS E NZ  1 
ATOM   4683 N N   . VAL C 3 173 ? 24.93504 14.92682  -7.47245  1.000 120.82221 ? 223 VAL E N   1 
ATOM   4684 C CA  . VAL C 3 173 ? 24.08465 15.04202  -8.65101  1.000 117.11043 ? 223 VAL E CA  1 
ATOM   4685 C C   . VAL C 3 173 ? 22.67307 14.65723  -8.23459  1.000 117.76574 ? 223 VAL E C   1 
ATOM   4686 O O   . VAL C 3 173 ? 22.44716 13.53840  -7.75584  1.000 128.92487 ? 223 VAL E O   1 
ATOM   4687 C CB  . VAL C 3 173 ? 24.57887 14.15696  -9.80575  1.000 111.26356 ? 223 VAL E CB  1 
ATOM   4688 C CG1 . VAL C 3 173 ? 23.56058 14.14323  -10.93620 1.000 115.87012 ? 223 VAL E CG1 1 
ATOM   4689 C CG2 . VAL C 3 173 ? 25.93297 14.64047  -10.30330 1.000 105.85560 ? 223 VAL E CG2 1 
ATOM   4690 N N   . ARG C 3 174 ? 21.72837 15.58076  -8.41955  1.000 110.20199 ? 224 ARG E N   1 
ATOM   4691 C CA  . ARG C 3 174 ? 20.34007 15.38771  -7.99732  1.000 115.79546 ? 224 ARG E CA  1 
ATOM   4692 C C   . ARG C 3 174 ? 20.26036 15.00841  -6.51965  1.000 127.28217 ? 224 ARG E C   1 
ATOM   4693 O O   . ARG C 3 174 ? 19.50635 14.11638  -6.12359  1.000 124.18262 ? 224 ARG E O   1 
ATOM   4694 C CB  . ARG C 3 174 ? 19.63624 14.34662  -8.87024  1.000 118.50361 ? 224 ARG E CB  1 
ATOM   4695 C CG  . ARG C 3 174 ? 19.58653 14.70709  -10.34534 1.000 110.87909 ? 224 ARG E CG  1 
ATOM   4696 C CD  . ARG C 3 174 ? 18.78393 13.68755  -11.13471 1.000 116.69638 ? 224 ARG E CD  1 
ATOM   4697 N NE  . ARG C 3 174 ? 17.39366 13.63765  -10.69832 1.000 119.01386 ? 224 ARG E NE  1 
ATOM   4698 C CZ  . ARG C 3 174 ? 16.41058 14.33717  -11.24843 1.000 115.95688 ? 224 ARG E CZ  1 
ATOM   4699 N NH1 . ARG C 3 174 ? 16.63002 15.15888  -12.26197 1.000 120.32164 ? 224 ARG E NH1 1 
ATOM   4700 N NH2 . ARG C 3 174 ? 15.17654 14.21025  -10.76875 1.000 105.96687 ? 224 ARG E NH2 1 
ATOM   4701 N N   . ASP C 3 175 ? 21.06145 15.69395  -5.69974  1.000 133.51261 ? 225 ASP E N   1 
ATOM   4702 C CA  . ASP C 3 175 ? 21.06371 15.52404  -4.24471  1.000 141.01233 ? 225 ASP E CA  1 
ATOM   4703 C C   . ASP C 3 175 ? 21.42377 14.09874  -3.82971  1.000 133.32894 ? 225 ASP E C   1 
ATOM   4704 O O   . ASP C 3 175 ? 20.94683 13.60174  -2.80668  1.000 134.88368 ? 225 ASP E O   1 
ATOM   4705 C CB  . ASP C 3 175 ? 19.71648 15.92999  -3.63655  1.000 143.73695 ? 225 ASP E CB  1 
ATOM   4706 C CG  . ASP C 3 175 ? 19.70193 17.36753  -3.15360  1.000 159.27482 ? 225 ASP E CG  1 
ATOM   4707 O OD1 . ASP C 3 175 ? 20.67563 18.10035  -3.42609  1.000 159.33938 ? 225 ASP E OD1 1 
ATOM   4708 O OD2 . ASP C 3 175 ? 18.71373 17.76497  -2.50153  1.000 172.34383 ? 225 ASP E OD2 1 
ATOM   4709 N N   . GLN C 3 176 ? 22.26728 13.42790  -4.61273  1.000 126.98805 ? 226 GLN E N   1 
ATOM   4710 C CA  . GLN C 3 176 ? 22.69460 12.06331  -4.30953  1.000 117.08616 ? 226 GLN E CA  1 
ATOM   4711 C C   . GLN C 3 176 ? 24.17707 11.93563  -4.62737  1.000 112.61708 ? 226 GLN E C   1 
ATOM   4712 O O   . GLN C 3 176 ? 24.56868 11.98476  -5.79751  1.000 122.16717 ? 226 GLN E O   1 
ATOM   4713 C CB  . GLN C 3 176 ? 21.88240 11.03573  -5.09827  1.000 109.69119 ? 226 GLN E CB  1 
ATOM   4714 C CG  . GLN C 3 176 ? 20.45020 10.86762  -4.62404  1.000 95.00677  ? 226 GLN E CG  1 
ATOM   4715 C CD  . GLN C 3 176 ? 20.35926 10.11609  -3.31026  1.000 111.12041 ? 226 GLN E CD  1 
ATOM   4716 O OE1 . GLN C 3 176 ? 21.20560 9.27629   -3.00229  1.000 108.59718 ? 226 GLN E OE1 1 
ATOM   4717 N NE2 . GLN C 3 176 ? 19.32949 10.41512  -2.52718  1.000 114.20071 ? 226 GLN E NE2 1 
ATOM   4718 N N   . GLU C 3 177 ? 25.00135 11.77369  -3.58942  1.000 101.93594 ? 227 GLU E N   1 
ATOM   4719 C CA  . GLU C 3 177 ? 26.42164 11.52864  -3.81683  1.000 109.39038 ? 227 GLU E CA  1 
ATOM   4720 C C   . GLU C 3 177 ? 26.67371 10.09805  -4.27628  1.000 107.16282 ? 227 GLU E C   1 
ATOM   4721 O O   . GLU C 3 177 ? 27.68504 9.82856   -4.93430  1.000 100.00875 ? 227 GLU E O   1 
ATOM   4722 C CB  . GLU C 3 177 ? 27.22323 11.83383  -2.55211  1.000 127.35186 ? 227 GLU E CB  1 
ATOM   4723 C CG  . GLU C 3 177 ? 27.18261 13.29699  -2.13232  1.000 124.83899 ? 227 GLU E CG  1 
ATOM   4724 C CD  . GLU C 3 177 ? 27.86680 13.53836  -0.80174  1.000 148.17457 ? 227 GLU E CD  1 
ATOM   4725 O OE1 . GLU C 3 177 ? 28.12266 12.55255  -0.07804  1.000 147.93781 ? 227 GLU E OE1 1 
ATOM   4726 O OE2 . GLU C 3 177 ? 28.13727 14.71233  -0.47335  1.000 153.70461 ? 227 GLU E OE2 1 
ATOM   4727 N N   . GLY C 3 178 ? 25.77344 9.17027   -3.93899  1.000 118.50064 ? 228 GLY E N   1 
ATOM   4728 C CA  . GLY C 3 178 ? 25.89095 7.81554   -4.42926  1.000 116.34564 ? 228 GLY E CA  1 
ATOM   4729 C C   . GLY C 3 178 ? 25.45719 7.68248   -5.87706  1.000 117.71341 ? 228 GLY E C   1 
ATOM   4730 O O   . GLY C 3 178 ? 24.76790 8.53626   -6.43401  1.000 116.52319 ? 228 GLY E O   1 
ATOM   4731 N N   . ARG C 3 179 ? 25.87126 6.57934   -6.49662  1.000 116.37759 ? 229 ARG E N   1 
ATOM   4732 C CA  . ARG C 3 179 ? 25.60455 6.33570   -7.90569  1.000 113.08843 ? 229 ARG E CA  1 
ATOM   4733 C C   . ARG C 3 179 ? 25.04536 4.93411   -8.09579  1.000 109.07758 ? 229 ARG E C   1 
ATOM   4734 O O   . ARG C 3 179 ? 25.36149 4.01216   -7.33890  1.000 111.13624 ? 229 ARG E O   1 
ATOM   4735 C CB  . ARG C 3 179 ? 26.87217 6.50649   -8.75516  1.000 107.21670 ? 229 ARG E CB  1 
ATOM   4736 C CG  . ARG C 3 179 ? 27.52728 7.86995   -8.62518  1.000 105.38303 ? 229 ARG E CG  1 
ATOM   4737 C CD  . ARG C 3 179 ? 26.79272 8.91959   -9.43980  1.000 104.61501 ? 229 ARG E CD  1 
ATOM   4738 N NE  . ARG C 3 179 ? 27.64195 10.06658  -9.73693  1.000 120.00465 ? 229 ARG E NE  1 
ATOM   4739 C CZ  . ARG C 3 179 ? 27.73633 11.14642  -8.97314  1.000 118.35401 ? 229 ARG E CZ  1 
ATOM   4740 N NH1 . ARG C 3 179 ? 27.04611 11.26147  -7.85034  1.000 108.26493 ? 229 ARG E NH1 1 
ATOM   4741 N NH2 . ARG C 3 179 ? 28.54496 12.13508  -9.34436  1.000 136.41506 ? 229 ARG E NH2 1 
ATOM   4742 N N   . ILE C 3 180 ? 24.20237 4.78787   -9.11503  1.000 108.71659 ? 230 ILE E N   1 
ATOM   4743 C CA  . ILE C 3 180 ? 23.65438 3.49879   -9.52163  1.000 101.75374 ? 230 ILE E CA  1 
ATOM   4744 C C   . ILE C 3 180 ? 23.89469 3.35839   -11.01758 1.000 93.93983  ? 230 ILE E C   1 
ATOM   4745 O O   . ILE C 3 180 ? 23.22125 4.01393   -11.82256 1.000 103.77148 ? 230 ILE E O   1 
ATOM   4746 C CB  . ILE C 3 180 ? 22.16033 3.36490   -9.19602  1.000 100.10470 ? 230 ILE E CB  1 
ATOM   4747 C CG1 . ILE C 3 180 ? 21.93352 3.38847   -7.68442  1.000 100.55076 ? 230 ILE E CG1 1 
ATOM   4748 C CG2 . ILE C 3 180 ? 21.59758 2.08532   -9.79535  1.000 86.54980  ? 230 ILE E CG2 1 
ATOM   4749 C CD1 . ILE C 3 180 ? 20.47894 3.25536   -7.28880  1.000 88.39847  ? 230 ILE E CD1 1 
ATOM   4750 N N   . ASN C 3 181 ? 24.84849 2.51058   -11.39184 1.000 97.03285  ? 231 ASN E N   1 
ATOM   4751 C CA  . ASN C 3 181 ? 25.12876 2.25947   -12.79804 1.000 99.62253  ? 231 ASN E CA  1 
ATOM   4752 C C   . ASN C 3 181 ? 24.11744 1.26687   -13.35666 1.000 92.13948  ? 231 ASN E C   1 
ATOM   4753 O O   . ASN C 3 181 ? 23.82826 0.24177   -12.73150 1.000 83.76267  ? 231 ASN E O   1 
ATOM   4754 C CB  . ASN C 3 181 ? 26.55145 1.73095   -12.97292 1.000 96.49143  ? 231 ASN E CB  1 
ATOM   4755 C CG  . ASN C 3 181 ? 27.60206 2.76681   -12.62787 1.000 98.84157  ? 231 ASN E CG  1 
ATOM   4756 O OD1 . ASN C 3 181 ? 27.28654 3.93541   -12.40251 1.000 91.95648  ? 231 ASN E OD1 1 
ATOM   4757 N ND2 . ASN C 3 181 ? 28.85986 2.34265   -12.58202 1.000 101.53055 ? 231 ASN E ND2 1 
ATOM   4758 N N   . TYR C 3 182 ? 23.58355 1.57120   -14.53473 1.000 90.35080  ? 232 TYR E N   1 
ATOM   4759 C CA  . TYR C 3 182 ? 22.54367 0.76377   -15.15668 1.000 95.90753  ? 232 TYR E CA  1 
ATOM   4760 C C   . TYR C 3 182 ? 23.14332 -0.09066  -16.26508 1.000 99.47925  ? 232 TYR E C   1 
ATOM   4761 O O   . TYR C 3 182 ? 23.93244 0.40120   -17.07881 1.000 103.70075 ? 232 TYR E O   1 
ATOM   4762 C CB  . TYR C 3 182 ? 21.43013 1.65083   -15.71457 1.000 91.81097  ? 232 TYR E CB  1 
ATOM   4763 C CG  . TYR C 3 182 ? 20.91299 2.67134   -14.72663 1.000 89.87322  ? 232 TYR E CG  1 
ATOM   4764 C CD1 . TYR C 3 182 ? 19.98920 2.31725   -13.75229 1.000 79.36933  ? 232 TYR E CD1 1 
ATOM   4765 C CD2 . TYR C 3 182 ? 21.35271 3.98783   -14.76501 1.000 93.68399  ? 232 TYR E CD2 1 
ATOM   4766 C CE1 . TYR C 3 182 ? 19.51425 3.24678   -12.84674 1.000 79.86512  ? 232 TYR E CE1 1 
ATOM   4767 C CE2 . TYR C 3 182 ? 20.88436 4.92404   -13.86357 1.000 96.80549  ? 232 TYR E CE2 1 
ATOM   4768 C CZ  . TYR C 3 182 ? 19.96577 4.54843   -12.90682 1.000 90.44749  ? 232 TYR E CZ  1 
ATOM   4769 O OH  . TYR C 3 182 ? 19.49768 5.47913   -12.00811 1.000 88.68771  ? 232 TYR E OH  1 
ATOM   4770 N N   . TYR C 3 183 ? 22.76733 -1.36737  -16.28964 1.000 88.57570  ? 233 TYR E N   1 
ATOM   4771 C CA  . TYR C 3 183 ? 23.22086 -2.30616  -17.30332 1.000 81.69177  ? 233 TYR E CA  1 
ATOM   4772 C C   . TYR C 3 183 ? 22.02202 -3.04515  -17.87930 1.000 82.88223  ? 233 TYR E C   1 
ATOM   4773 O O   . TYR C 3 183 ? 21.00897 -3.24139  -17.20232 1.000 74.69545  ? 233 TYR E O   1 
ATOM   4774 C CB  . TYR C 3 183 ? 24.23269 -3.30968  -16.73273 1.000 80.48272  ? 233 TYR E CB  1 
ATOM   4775 C CG  . TYR C 3 183 ? 25.37045 -2.67023  -15.96856 1.000 81.55745  ? 233 TYR E CG  1 
ATOM   4776 C CD1 . TYR C 3 183 ? 26.51401 -2.23444  -16.62458 1.000 96.26296  ? 233 TYR E CD1 1 
ATOM   4777 C CD2 . TYR C 3 183 ? 25.30291 -2.50550  -14.59154 1.000 89.52935  ? 233 TYR E CD2 1 
ATOM   4778 C CE1 . TYR C 3 183 ? 27.55790 -1.65115  -15.93128 1.000 96.00435  ? 233 TYR E CE1 1 
ATOM   4779 C CE2 . TYR C 3 183 ? 26.34165 -1.92272  -13.88956 1.000 88.79798  ? 233 TYR E CE2 1 
ATOM   4780 C CZ  . TYR C 3 183 ? 27.46644 -1.49787  -14.56458 1.000 91.49026  ? 233 TYR E CZ  1 
ATOM   4781 O OH  . TYR C 3 183 ? 28.50357 -0.91742  -13.87126 1.000 104.50375 ? 233 TYR E OH  1 
ATOM   4782 N N   . TRP C 3 184 ? 22.14586 -3.45182  -19.14087 1.000 98.16669  ? 234 TRP E N   1 
ATOM   4783 C CA  . TRP C 3 184 ? 21.06134 -4.11635  -19.84653 1.000 89.57645  ? 234 TRP E CA  1 
ATOM   4784 C C   . TRP C 3 184 ? 21.62330 -5.22905  -20.71869 1.000 91.70902  ? 234 TRP E C   1 
ATOM   4785 O O   . TRP C 3 184 ? 22.80344 -5.23266  -21.07806 1.000 92.02670  ? 234 TRP E O   1 
ATOM   4786 C CB  . TRP C 3 184 ? 20.26063 -3.12997  -20.70831 1.000 96.21307  ? 234 TRP E CB  1 
ATOM   4787 C CG  . TRP C 3 184 ? 21.02898 -2.61380  -21.88829 1.000 94.00951  ? 234 TRP E CG  1 
ATOM   4788 C CD1 . TRP C 3 184 ? 21.86658 -1.53735  -21.91269 1.000 99.53707  ? 234 TRP E CD1 1 
ATOM   4789 C CD2 . TRP C 3 184 ? 21.03374 -3.15537  -23.21521 1.000 101.27916 ? 234 TRP E CD2 1 
ATOM   4790 N NE1 . TRP C 3 184 ? 22.39192 -1.37387  -23.17158 1.000 97.95810  ? 234 TRP E NE1 1 
ATOM   4791 C CE2 . TRP C 3 184 ? 21.89644 -2.35469  -23.98979 1.000 104.32214 ? 234 TRP E CE2 1 
ATOM   4792 C CE3 . TRP C 3 184 ? 20.39272 -4.23923  -23.82301 1.000 98.87171  ? 234 TRP E CE3 1 
ATOM   4793 C CZ2 . TRP C 3 184 ? 22.13398 -2.60320  -25.34002 1.000 97.33454  ? 234 TRP E CZ2 1 
ATOM   4794 C CZ3 . TRP C 3 184 ? 20.62961 -4.48392  -25.16383 1.000 86.00853  ? 234 TRP E CZ3 1 
ATOM   4795 C CH2 . TRP C 3 184 ? 21.49233 -3.66939  -25.90721 1.000 92.22388  ? 234 TRP E CH2 1 
ATOM   4796 N N   . THR C 3 185 ? 20.75411 -6.18080  -21.05216 1.000 89.88577  ? 235 THR E N   1 
ATOM   4797 C CA  . THR C 3 185 ? 21.09238 -7.25070  -21.97819 1.000 82.31987  ? 235 THR E CA  1 
ATOM   4798 C C   . THR C 3 185 ? 19.81168 -7.76294  -22.61888 1.000 77.44605  ? 235 THR E C   1 
ATOM   4799 O O   . THR C 3 185 ? 18.70905 -7.54881  -22.10817 1.000 75.47948  ? 235 THR E O   1 
ATOM   4800 C CB  . THR C 3 185 ? 21.83829 -8.39872  -21.28634 1.000 89.97325  ? 235 THR E CB  1 
ATOM   4801 O OG1 . THR C 3 185 ? 22.27915 -9.34305  -22.26997 1.000 79.03451  ? 235 THR E OG1 1 
ATOM   4802 C CG2 . THR C 3 185 ? 20.92927 -9.10363  -20.29230 1.000 87.97690  ? 235 THR E CG2 1 
ATOM   4803 N N   . LEU C 3 186 ? 19.97012 -8.44279  -23.74963 1.000 84.62279  ? 236 LEU E N   1 
ATOM   4804 C CA  . LEU C 3 186 ? 18.85359 -9.01724  -24.48640 1.000 82.63037  ? 236 LEU E CA  1 
ATOM   4805 C C   . LEU C 3 186 ? 18.88612 -10.53103 -24.33914 1.000 79.79521  ? 236 LEU E C   1 
ATOM   4806 O O   . LEU C 3 186 ? 19.91228 -11.16408 -24.60959 1.000 81.91559  ? 236 LEU E O   1 
ATOM   4807 C CB  . LEU C 3 186 ? 18.90639 -8.61988  -25.96306 1.000 68.67746  ? 236 LEU E CB  1 
ATOM   4808 C CG  . LEU C 3 186 ? 18.15090 -7.33981  -26.32830 1.000 68.68529  ? 236 LEU E CG  1 
ATOM   4809 C CD1 . LEU C 3 186 ? 18.57218 -6.83671  -27.69930 1.000 80.77410  ? 236 LEU E CD1 1 
ATOM   4810 C CD2 . LEU C 3 186 ? 16.64678 -7.56506  -26.27327 1.000 75.83658  ? 236 LEU E CD2 1 
ATOM   4811 N N   . LEU C 3 187 ? 17.76566 -11.10481 -23.91034 1.000 79.35231  ? 237 LEU E N   1 
ATOM   4812 C CA  . LEU C 3 187 ? 17.66407 -12.53511 -23.64655 1.000 81.85865  ? 237 LEU E CA  1 
ATOM   4813 C C   . LEU C 3 187 ? 17.06371 -13.21851 -24.86948 1.000 83.67599  ? 237 LEU E C   1 
ATOM   4814 O O   . LEU C 3 187 ? 15.88625 -13.01901 -25.18617 1.000 79.38275  ? 237 LEU E O   1 
ATOM   4815 C CB  . LEU C 3 187 ? 16.82267 -12.79840 -22.39958 1.000 80.15371  ? 237 LEU E CB  1 
ATOM   4816 C CG  . LEU C 3 187 ? 16.91866 -14.20640 -21.80888 1.000 69.16880  ? 237 LEU E CG  1 
ATOM   4817 C CD1 . LEU C 3 187 ? 18.32585 -14.48051 -21.29943 1.000 67.25583  ? 237 LEU E CD1 1 
ATOM   4818 C CD2 . LEU C 3 187 ? 15.89719 -14.39422 -20.69919 1.000 73.43907  ? 237 LEU E CD2 1 
ATOM   4819 N N   . GLU C 3 188 ? 17.87590 -14.01668 -25.55335 1.000 103.19723 ? 238 GLU E N   1 
ATOM   4820 C CA  . GLU C 3 188 ? 17.38369 -14.78649 -26.68410 1.000 98.94459  ? 238 GLU E CA  1 
ATOM   4821 C C   . GLU C 3 188 ? 16.35970 -15.80979 -26.19629 1.000 93.21579  ? 238 GLU E C   1 
ATOM   4822 O O   . GLU C 3 188 ? 16.49575 -16.33906 -25.08657 1.000 94.82536  ? 238 GLU E O   1 
ATOM   4823 C CB  . GLU C 3 188 ? 18.54607 -15.49022 -27.38901 1.000 86.64318  ? 238 GLU E CB  1 
ATOM   4824 C CG  . GLU C 3 188 ? 18.25081 -15.96408 -28.80401 1.000 124.47680 ? 238 GLU E CG  1 
ATOM   4825 C CD  . GLU C 3 188 ? 18.14994 -17.47460 -28.90555 1.000 137.42871 ? 238 GLU E CD  1 
ATOM   4826 O OE1 . GLU C 3 188 ? 18.68940 -18.16950 -28.01840 1.000 123.30343 ? 238 GLU E OE1 1 
ATOM   4827 O OE2 . GLU C 3 188 ? 17.53456 -17.96675 -29.87568 1.000 112.70703 ? 238 GLU E OE2 1 
ATOM   4828 N N   . PRO C 3 189 ? 15.31626 -16.09293 -26.97768 1.000 98.22878  ? 239 PRO E N   1 
ATOM   4829 C CA  . PRO C 3 189 ? 14.34431 -17.11001 -26.55812 1.000 97.98690  ? 239 PRO E CA  1 
ATOM   4830 C C   . PRO C 3 189 ? 15.01547 -18.45451 -26.32048 1.000 88.81526  ? 239 PRO E C   1 
ATOM   4831 O O   . PRO C 3 189 ? 15.91384 -18.86359 -27.05905 1.000 85.19402  ? 239 PRO E O   1 
ATOM   4832 C CB  . PRO C 3 189 ? 13.36316 -17.16664 -27.73383 1.000 89.87979  ? 239 PRO E CB  1 
ATOM   4833 C CG  . PRO C 3 189 ? 13.44666 -15.81076 -28.34468 1.000 86.73175  ? 239 PRO E CG  1 
ATOM   4834 C CD  . PRO C 3 189 ? 14.88050 -15.38391 -28.19383 1.000 91.36081  ? 239 PRO E CD  1 
ATOM   4835 N N   . GLY C 3 190 ? 14.56690 -19.14164 -25.27251 1.000 77.07445  ? 240 GLY E N   1 
ATOM   4836 C CA  . GLY C 3 190 ? 15.17409 -20.38757 -24.86125 1.000 89.94064  ? 240 GLY E CA  1 
ATOM   4837 C C   . GLY C 3 190 ? 16.38339 -20.24729 -23.96407 1.000 73.62937  ? 240 GLY E C   1 
ATOM   4838 O O   . GLY C 3 190 ? 17.01327 -21.26217 -23.64108 1.000 81.72539  ? 240 GLY E O   1 
ATOM   4839 N N   . ASP C 3 191 ? 16.72968 -19.03225 -23.55109 1.000 66.98083  ? 241 ASP E N   1 
ATOM   4840 C CA  . ASP C 3 191 ? 17.87102 -18.78691 -22.68456 1.000 77.77809  ? 241 ASP E CA  1 
ATOM   4841 C C   . ASP C 3 191 ? 17.39748 -18.29039 -21.32415 1.000 92.06362  ? 241 ASP E C   1 
ATOM   4842 O O   . ASP C 3 191 ? 16.31679 -17.70715 -21.19720 1.000 86.84083  ? 241 ASP E O   1 
ATOM   4843 C CB  . ASP C 3 191 ? 18.82799 -17.76683 -23.31034 1.000 73.35362  ? 241 ASP E CB  1 
ATOM   4844 C CG  . ASP C 3 191 ? 20.22599 -17.84521 -22.72873 1.000 93.45444  ? 241 ASP E CG  1 
ATOM   4845 O OD1 . ASP C 3 191 ? 20.52689 -18.83793 -22.03234 1.000 94.79447  ? 241 ASP E OD1 1 
ATOM   4846 O OD2 . ASP C 3 191 ? 21.02450 -16.91515 -22.97014 1.000 90.20185  ? 241 ASP E OD2 1 
ATOM   4847 N N   . THR C 3 192 ? 18.21799 -18.53146 -20.30528 1.000 76.81815  ? 242 THR E N   1 
ATOM   4848 C CA  . THR C 3 192 ? 17.91209 -18.14804 -18.93530 1.000 72.18887  ? 242 THR E CA  1 
ATOM   4849 C C   . THR C 3 192 ? 19.01416 -17.24533 -18.39816 1.000 79.75399  ? 242 THR E C   1 
ATOM   4850 O O   . THR C 3 192 ? 20.20258 -17.50139 -18.61708 1.000 86.16581  ? 242 THR E O   1 
ATOM   4851 C CB  . THR C 3 192 ? 17.75435 -19.38407 -18.03880 1.000 77.36306  ? 242 THR E CB  1 
ATOM   4852 O OG1 . THR C 3 192 ? 16.76618 -20.25885 -18.59722 1.000 87.49059  ? 242 THR E OG1 1 
ATOM   4853 C CG2 . THR C 3 192 ? 17.33742 -18.98792 -16.63124 1.000 80.87058  ? 242 THR E CG2 1 
ATOM   4854 N N   . ILE C 3 193 ? 18.61202 -16.18668 -17.69914 1.000 71.47140  ? 243 ILE E N   1 
ATOM   4855 C CA  . ILE C 3 193 ? 19.52887 -15.21414 -17.11520 1.000 77.27902  ? 243 ILE E CA  1 
ATOM   4856 C C   . ILE C 3 193 ? 19.51531 -15.39304 -15.60234 1.000 81.05456  ? 243 ILE E C   1 
ATOM   4857 O O   . ILE C 3 193 ? 18.44464 -15.48686 -14.99063 1.000 79.38418  ? 243 ILE E O   1 
ATOM   4858 C CB  . ILE C 3 193 ? 19.15406 -13.77651 -17.52249 1.000 73.72556  ? 243 ILE E CB  1 
ATOM   4859 C CG1 . ILE C 3 193 ? 20.10966 -12.76222 -16.89133 1.000 64.44515  ? 243 ILE E CG1 1 
ATOM   4860 C CG2 . ILE C 3 193 ? 17.69732 -13.46406 -17.18447 1.000 69.75814  ? 243 ILE E CG2 1 
ATOM   4861 C CD1 . ILE C 3 193 ? 19.93059 -11.35844 -17.42462 1.000 71.27630  ? 243 ILE E CD1 1 
ATOM   4862 N N   . ILE C 3 194 ? 20.70180 -15.45946 -15.00270 1.000 80.99620  ? 244 ILE E N   1 
ATOM   4863 C CA  . ILE C 3 194 ? 20.86169 -15.75429 -13.58255 1.000 73.28042  ? 244 ILE E CA  1 
ATOM   4864 C C   . ILE C 3 194 ? 21.35416 -14.50282 -12.87063 1.000 80.24044  ? 244 ILE E C   1 
ATOM   4865 O O   . ILE C 3 194 ? 22.29450 -13.84564 -13.33360 1.000 76.89802  ? 244 ILE E O   1 
ATOM   4866 C CB  . ILE C 3 194 ? 21.83463 -16.92374 -13.35521 1.000 71.16913  ? 244 ILE E CB  1 
ATOM   4867 C CG1 . ILE C 3 194 ? 21.55814 -18.05344 -14.34743 1.000 72.09582  ? 244 ILE E CG1 1 
ATOM   4868 C CG2 . ILE C 3 194 ? 21.73256 -17.42932 -11.92382 1.000 67.95206  ? 244 ILE E CG2 1 
ATOM   4869 C CD1 . ILE C 3 194 ? 22.56102 -19.18239 -14.27100 1.000 64.12893  ? 244 ILE E CD1 1 
ATOM   4870 N N   . PHE C 3 195 ? 20.72099 -14.17696 -11.74666 1.000 84.76560  ? 245 PHE E N   1 
ATOM   4871 C CA  . PHE C 3 195 ? 21.14032 -13.07792 -10.88580 1.000 75.08364  ? 245 PHE E CA  1 
ATOM   4872 C C   . PHE C 3 195 ? 21.60112 -13.64740 -9.55104  1.000 73.54661  ? 245 PHE E C   1 
ATOM   4873 O O   . PHE C 3 195 ? 20.83123 -14.32825 -8.86536  1.000 67.95695  ? 245 PHE E O   1 
ATOM   4874 C CB  . PHE C 3 195 ? 20.00428 -12.07739 -10.67173 1.000 65.47086  ? 245 PHE E CB  1 
ATOM   4875 C CG  . PHE C 3 195 ? 19.67355 -11.26250 -11.88719 1.000 80.17601  ? 245 PHE E CG  1 
ATOM   4876 C CD1 . PHE C 3 195 ? 20.32040 -10.06190 -12.12789 1.000 77.61839  ? 245 PHE E CD1 1 
ATOM   4877 C CD2 . PHE C 3 195 ? 18.70956 -11.69086 -12.78402 1.000 85.89992  ? 245 PHE E CD2 1 
ATOM   4878 C CE1 . PHE C 3 195 ? 20.01698 -9.30658  -13.24394 1.000 83.59039  ? 245 PHE E CE1 1 
ATOM   4879 C CE2 . PHE C 3 195 ? 18.40108 -10.93993 -13.90214 1.000 94.76408  ? 245 PHE E CE2 1 
ATOM   4880 C CZ  . PHE C 3 195 ? 19.05586 -9.74613  -14.13233 1.000 95.15185  ? 245 PHE E CZ  1 
ATOM   4881 N N   . GLU C 3 196 ? 22.85105 -13.36961 -9.18686  1.000 77.35775  ? 246 GLU E N   1 
ATOM   4882 C CA  . GLU C 3 196 ? 23.39700 -13.75274 -7.89163  1.000 83.77214  ? 246 GLU E CA  1 
ATOM   4883 C C   . GLU C 3 196 ? 24.08585 -12.54867 -7.27046  1.000 87.85698  ? 246 GLU E C   1 
ATOM   4884 O O   . GLU C 3 196 ? 24.96072 -11.94097 -7.89593  1.000 92.82099  ? 246 GLU E O   1 
ATOM   4885 C CB  . GLU C 3 196 ? 24.38082 -14.91948 -8.02060  1.000 78.03201  ? 246 GLU E CB  1 
ATOM   4886 C CG  . GLU C 3 196 ? 23.71784 -16.26078 -8.26834  1.000 89.10970  ? 246 GLU E CG  1 
ATOM   4887 C CD  . GLU C 3 196 ? 24.69916 -17.41255 -8.20558  1.000 116.48311 ? 246 GLU E CD  1 
ATOM   4888 O OE1 . GLU C 3 196 ? 25.92108 -17.15885 -8.25897  1.000 122.60482 ? 246 GLU E OE1 1 
ATOM   4889 O OE2 . GLU C 3 196 ? 24.24800 -18.57100 -8.09384  1.000 124.13250 ? 246 GLU E OE2 1 
ATOM   4890 N N   . ALA C 3 197 ? 23.69808 -12.21112 -6.04266  1.000 78.57308  ? 247 ALA E N   1 
ATOM   4891 C CA  . ALA C 3 197 ? 24.25721 -11.04399 -5.37798  1.000 91.74031  ? 247 ALA E CA  1 
ATOM   4892 C C   . ALA C 3 197 ? 24.02151 -11.14619 -3.87888  1.000 89.64127  ? 247 ALA E C   1 
ATOM   4893 O O   . ALA C 3 197 ? 23.02850 -11.72462 -3.42970  1.000 81.98703  ? 247 ALA E O   1 
ATOM   4894 C CB  . ALA C 3 197 ? 23.64909 -9.74619  -5.92240  1.000 84.18293  ? 247 ALA E CB  1 
ATOM   4895 N N   . ASN C 3 198 ? 24.95193 -10.57775 -3.11324  1.000 84.92683  ? 248 ASN E N   1 
ATOM   4896 C CA  . ASN C 3 198 ? 24.80824 -10.43399 -1.67152  1.000 86.20393  ? 248 ASN E CA  1 
ATOM   4897 C C   . ASN C 3 198 ? 24.38688 -9.02605  -1.27005  1.000 87.68494  ? 248 ASN E C   1 
ATOM   4898 O O   . ASN C 3 198 ? 24.33640 -8.72015  -0.07429  1.000 67.80444  ? 248 ASN E O   1 
ATOM   4899 C CB  . ASN C 3 198 ? 26.11316 -10.81359 -0.96560  1.000 72.27832  ? 248 ASN E CB  1 
ATOM   4900 C CG  . ASN C 3 198 ? 27.28051 -9.93077  -1.37295  1.000 82.44662  ? 248 ASN E CG  1 
ATOM   4901 O OD1 . ASN C 3 198 ? 27.16556 -9.09967  -2.27449  1.000 82.33768  ? 248 ASN E OD1 1 
ATOM   4902 N ND2 . ASN C 3 198 ? 28.41493 -10.10952 -0.70594  1.000 72.33217  ? 248 ASN E ND2 1 
ATOM   4903 N N   . GLY C 3 199 ? 24.09777 -8.17067  -2.23451  1.000 86.50991  ? 249 GLY E N   1 
ATOM   4904 C CA  . GLY C 3 199 ? 23.70081 -6.80499  -1.95578  1.000 81.11673  ? 249 GLY E CA  1 
ATOM   4905 C C   . GLY C 3 199 ? 24.08076 -5.90017  -3.10962  1.000 74.18687  ? 249 GLY E C   1 
ATOM   4906 O O   . GLY C 3 199 ? 24.69435 -6.32181  -4.08650  1.000 94.20401  ? 249 GLY E O   1 
ATOM   4907 N N   . ASN C 3 200 ? 23.69662 -4.62954  -2.96642  1.000 69.90949  ? 250 ASN E N   1 
ATOM   4908 C CA  . ASN C 3 200 ? 23.99131 -3.59011  -3.95638  1.000 73.41638  ? 250 ASN E CA  1 
ATOM   4909 C C   . ASN C 3 200 ? 23.45289 -3.96026  -5.33705  1.000 82.91008  ? 250 ASN E C   1 
ATOM   4910 O O   . ASN C 3 200 ? 24.09541 -3.71436  -6.35994  1.000 84.74322  ? 250 ASN E O   1 
ATOM   4911 C CB  . ASN C 3 200 ? 25.49286 -3.30079  -4.02716  1.000 71.78086  ? 250 ASN E CB  1 
ATOM   4912 C CG  . ASN C 3 200 ? 26.08732 -2.96677  -2.67655  1.000 86.45831  ? 250 ASN E CG  1 
ATOM   4913 O OD1 . ASN C 3 200 ? 25.89474 -3.69562  -1.70398  1.000 96.71107  ? 250 ASN E OD1 1 
ATOM   4914 N ND2 . ASN C 3 200 ? 26.81848 -1.86054  -2.60919  1.000 97.89658  ? 250 ASN E ND2 1 
ATOM   4915 N N   . LEU C 3 201 ? 22.26492 -4.55749  -5.37114  1.000 73.46247  ? 251 LEU E N   1 
ATOM   4916 C CA  . LEU C 3 201 ? 21.64417 -4.99282  -6.61430  1.000 68.42446  ? 251 LEU E CA  1 
ATOM   4917 C C   . LEU C 3 201 ? 20.27164 -4.35350  -6.75583  1.000 75.69207  ? 251 LEU E C   1 
ATOM   4918 O O   . LEU C 3 201 ? 19.42688 -4.48099  -5.86318  1.000 76.68540  ? 251 LEU E O   1 
ATOM   4919 C CB  . LEU C 3 201 ? 21.51903 -6.51830  -6.66746  1.000 70.92421  ? 251 LEU E CB  1 
ATOM   4920 C CG  . LEU C 3 201 ? 20.54442 -7.07021  -7.71188  1.000 68.75515  ? 251 LEU E CG  1 
ATOM   4921 C CD1 . LEU C 3 201 ? 21.04099 -6.78790  -9.12265  1.000 76.88513  ? 251 LEU E CD1 1 
ATOM   4922 C CD2 . LEU C 3 201 ? 20.31686 -8.55976  -7.50695  1.000 85.74954  ? 251 LEU E CD2 1 
ATOM   4923 N N   . ILE C 3 202 ? 20.05534 -3.67313  -7.87597  1.000 82.22776  ? 252 ILE E N   1 
ATOM   4924 C CA  . ILE C 3 202 ? 18.74080 -3.15073  -8.24017  1.000 79.95714  ? 252 ILE E CA  1 
ATOM   4925 C C   . ILE C 3 202 ? 18.13032 -4.19671  -9.16714  1.000 71.16275  ? 252 ILE E C   1 
ATOM   4926 O O   . ILE C 3 202 ? 18.30142 -4.15881  -10.38619 1.000 82.08963  ? 252 ILE E O   1 
ATOM   4927 C CB  . ILE C 3 202 ? 18.83174 -1.77245  -8.89172  1.000 77.84455  ? 252 ILE E CB  1 
ATOM   4928 C CG1 . ILE C 3 202 ? 19.70379 -0.83896  -8.04872  1.000 70.23261  ? 252 ILE E CG1 1 
ATOM   4929 C CG2 . ILE C 3 202 ? 17.44265 -1.17813  -9.07701  1.000 81.90045  ? 252 ILE E CG2 1 
ATOM   4930 C CD1 . ILE C 3 202 ? 19.19481 -0.63069  -6.63922  1.000 73.49347  ? 252 ILE E CD1 1 
ATOM   4931 N N   . ALA C 3 203 ? 17.41751 -5.15031  -8.57627  1.000 80.26361  ? 253 ALA E N   1 
ATOM   4932 C CA  . ALA C 3 203 ? 16.90326 -6.27853  -9.33786  1.000 64.29945  ? 253 ALA E CA  1 
ATOM   4933 C C   . ALA C 3 203 ? 15.81053 -5.81752  -10.30039 1.000 82.51215  ? 253 ALA E C   1 
ATOM   4934 O O   . ALA C 3 203 ? 15.05474 -4.89444  -9.98425  1.000 82.61310  ? 253 ALA E O   1 
ATOM   4935 C CB  . ALA C 3 203 ? 16.35238 -7.35038  -8.40080  1.000 72.70749  ? 253 ALA E CB  1 
ATOM   4936 N N   . PRO C 3 204 ? 15.71214 -6.42948  -11.48203 1.000 90.28926  ? 254 PRO E N   1 
ATOM   4937 C CA  . PRO C 3 204 ? 14.65265 -6.04528  -12.42187 1.000 79.74571  ? 254 PRO E CA  1 
ATOM   4938 C C   . PRO C 3 204 ? 13.27433 -6.37284  -11.87041 1.000 80.81081  ? 254 PRO E C   1 
ATOM   4939 O O   . PRO C 3 204 ? 13.08589 -7.34535  -11.13619 1.000 80.18538  ? 254 PRO E O   1 
ATOM   4940 C CB  . PRO C 3 204 ? 14.96404 -6.87699  -13.67379 1.000 82.56305  ? 254 PRO E CB  1 
ATOM   4941 C CG  . PRO C 3 204 ? 16.38927 -7.30107  -13.52040 1.000 78.30255  ? 254 PRO E CG  1 
ATOM   4942 C CD  . PRO C 3 204 ? 16.61983 -7.43754  -12.05127 1.000 82.24126  ? 254 PRO E CD  1 
ATOM   4943 N N   . TRP C 3 205 ? 12.30380 -5.53788  -12.23428 1.000 76.06590  ? 255 TRP E N   1 
ATOM   4944 C CA  . TRP C 3 205 ? 10.90702 -5.74255  -11.87624 1.000 87.63993  ? 255 TRP E CA  1 
ATOM   4945 C C   . TRP C 3 205 ? 10.04083 -6.03196  -13.09171 1.000 92.52970  ? 255 TRP E C   1 
ATOM   4946 O O   . TRP C 3 205 ? 9.26360  -6.99130  -13.08619 1.000 90.27730  ? 255 TRP E O   1 
ATOM   4947 C CB  . TRP C 3 205 ? 10.37069 -4.51245  -11.12607 1.000 93.67006  ? 255 TRP E CB  1 
ATOM   4948 C CG  . TRP C 3 205 ? 9.03497  -4.72074  -10.46389 1.000 90.56923  ? 255 TRP E CG  1 
ATOM   4949 C CD1 . TRP C 3 205 ? 8.31128  -5.87838  -10.41230 1.000 95.64283  ? 255 TRP E CD1 1 
ATOM   4950 C CD2 . TRP C 3 205 ? 8.26948  -3.73943  -9.75356  1.000 83.79663  ? 255 TRP E CD2 1 
ATOM   4951 N NE1 . TRP C 3 205 ? 7.14278  -5.67652  -9.71870  1.000 84.75816  ? 255 TRP E NE1 1 
ATOM   4952 C CE2 . TRP C 3 205 ? 7.09331  -4.37205  -9.30304  1.000 91.05743  ? 255 TRP E CE2 1 
ATOM   4953 C CE3 . TRP C 3 205 ? 8.46446  -2.38732  -9.45530  1.000 91.69233  ? 255 TRP E CE3 1 
ATOM   4954 C CZ2 . TRP C 3 205 ? 6.11670  -3.69887  -8.57120  1.000 97.62268  ? 255 TRP E CZ2 1 
ATOM   4955 C CZ3 . TRP C 3 205 ? 7.49333  -1.72062  -8.72880  1.000 100.47238 ? 255 TRP E CZ3 1 
ATOM   4956 C CH2 . TRP C 3 205 ? 6.33477  -2.37705  -8.29503  1.000 99.60691  ? 255 TRP E CH2 1 
ATOM   4957 N N   . TYR C 3 206 ? 10.16274 -5.22602  -14.14209 1.000 90.82863  ? 256 TYR E N   1 
ATOM   4958 C CA  . TYR C 3 206 ? 9.42453  -5.41937  -15.38019 1.000 96.30360  ? 256 TYR E CA  1 
ATOM   4959 C C   . TYR C 3 206 ? 10.39889 -5.49640  -16.54626 1.000 100.26537 ? 256 TYR E C   1 
ATOM   4960 O O   . TYR C 3 206 ? 11.38002 -4.74785  -16.59877 1.000 95.69417  ? 256 TYR E O   1 
ATOM   4961 C CB  . TYR C 3 206 ? 8.41750  -4.28668  -15.60907 1.000 96.70039  ? 256 TYR E CB  1 
ATOM   4962 C CG  . TYR C 3 206 ? 7.09492  -4.49210  -14.90576 1.000 97.58893  ? 256 TYR E CG  1 
ATOM   4963 C CD1 . TYR C 3 206 ? 6.91061  -4.07420  -13.59462 1.000 100.51148 ? 256 TYR E CD1 1 
ATOM   4964 C CD2 . TYR C 3 206 ? 6.03009  -5.10371  -15.55390 1.000 106.56713 ? 256 TYR E CD2 1 
ATOM   4965 C CE1 . TYR C 3 206 ? 5.70238  -4.26049  -12.94793 1.000 99.21348  ? 256 TYR E CE1 1 
ATOM   4966 C CE2 . TYR C 3 206 ? 4.81890  -5.29435  -14.91606 1.000 109.11076 ? 256 TYR E CE2 1 
ATOM   4967 C CZ  . TYR C 3 206 ? 4.66037  -4.87083  -13.61358 1.000 96.79895  ? 256 TYR E CZ  1 
ATOM   4968 O OH  . TYR C 3 206 ? 3.45552  -5.05903  -12.97586 1.000 95.59858  ? 256 TYR E OH  1 
ATOM   4969 N N   . ALA C 3 207 ? 10.12830 -6.40936  -17.47306 1.000 95.37955  ? 257 ALA E N   1 
ATOM   4970 C CA  . ALA C 3 207 ? 10.93467 -6.58850  -18.66972 1.000 91.59138  ? 257 ALA E CA  1 
ATOM   4971 C C   . ALA C 3 207 ? 10.06883 -6.37580  -19.90403 1.000 105.48909 ? 257 ALA E C   1 
ATOM   4972 O O   . ALA C 3 207 ? 8.83734  -6.34259  -19.83278 1.000 99.09881  ? 257 ALA E O   1 
ATOM   4973 C CB  . ALA C 3 207 ? 11.58292 -7.97847  -18.70219 1.000 93.05159  ? 257 ALA E CB  1 
ATOM   4974 N N   . PHE C 3 208 ? 10.72981 -6.22870  -21.04932 1.000 111.08680 ? 258 PHE E N   1 
ATOM   4975 C CA  . PHE C 3 208 ? 10.05679 -5.95715  -22.31268 1.000 99.75988  ? 258 PHE E CA  1 
ATOM   4976 C C   . PHE C 3 208 ? 10.41787 -7.03679  -23.32131 1.000 104.62154 ? 258 PHE E C   1 
ATOM   4977 O O   . PHE C 3 208 ? 11.60013 -7.25217  -23.60961 1.000 102.14658 ? 258 PHE E O   1 
ATOM   4978 C CB  . PHE C 3 208 ? 10.43467 -4.57591  -22.85023 1.000 90.66571  ? 258 PHE E CB  1 
ATOM   4979 C CG  . PHE C 3 208 ? 10.30590 -3.47680  -21.83782 1.000 99.28587  ? 258 PHE E CG  1 
ATOM   4980 C CD1 . PHE C 3 208 ? 9.08206  -2.87187  -21.60579 1.000 108.75555 ? 258 PHE E CD1 1 
ATOM   4981 C CD2 . PHE C 3 208 ? 11.40940 -3.04297  -21.12264 1.000 107.27331 ? 258 PHE E CD2 1 
ATOM   4982 C CE1 . PHE C 3 208 ? 8.95944  -1.85886  -20.67599 1.000 110.71782 ? 258 PHE E CE1 1 
ATOM   4983 C CE2 . PHE C 3 208 ? 11.29299 -2.02970  -20.19121 1.000 117.29961 ? 258 PHE E CE2 1 
ATOM   4984 C CZ  . PHE C 3 208 ? 10.06602 -1.43713  -19.96849 1.000 114.99457 ? 258 PHE E CZ  1 
ATOM   4985 N N   . ALA C 3 209 ? 9.40068  -7.70654  -23.85663 1.000 101.73245 ? 259 ALA E N   1 
ATOM   4986 C CA  . ALA C 3 209 ? 9.58076  -8.64937  -24.95055 1.000 95.06729  ? 259 ALA E CA  1 
ATOM   4987 C C   . ALA C 3 209 ? 9.40866  -7.90859  -26.26925 1.000 108.22911 ? 259 ALA E C   1 
ATOM   4988 O O   . ALA C 3 209 ? 8.39373  -7.23755  -26.48267 1.000 111.39756 ? 259 ALA E O   1 
ATOM   4989 C CB  . ALA C 3 209 ? 8.58237  -9.80273  -24.84783 1.000 80.03442  ? 259 ALA E CB  1 
ATOM   4990 N N   . LEU C 3 210 ? 10.39879 -8.02892  -27.14903 1.000 102.43547 ? 260 LEU E N   1 
ATOM   4991 C CA  . LEU C 3 210 ? 10.44031 -7.24200  -28.37030 1.000 103.04471 ? 260 LEU E CA  1 
ATOM   4992 C C   . LEU C 3 210 ? 10.75096 -8.12602  -29.56882 1.000 125.60988 ? 260 LEU E C   1 
ATOM   4993 O O   . LEU C 3 210 ? 11.36071 -9.19142  -29.44016 1.000 110.10963 ? 260 LEU E O   1 
ATOM   4994 C CB  . LEU C 3 210 ? 11.48122 -6.11517  -28.26939 1.000 99.24713  ? 260 LEU E CB  1 
ATOM   4995 C CG  . LEU C 3 210 ? 12.88145 -6.50060  -27.78360 1.000 98.53469  ? 260 LEU E CG  1 
ATOM   4996 C CD1 . LEU C 3 210 ? 13.81326 -6.79580  -28.95192 1.000 96.75588  ? 260 LEU E CD1 1 
ATOM   4997 C CD2 . LEU C 3 210 ? 13.45862 -5.40791  -26.89754 1.000 105.60804 ? 260 LEU E CD2 1 
ATOM   4998 N N   . SER C 3 211 ? 10.31443 -7.66592  -30.73924 1.000 138.11307 ? 261 SER E N   1 
ATOM   4999 C CA  . SER C 3 211 ? 10.63350 -8.29195  -32.01187 1.000 118.22363 ? 261 SER E CA  1 
ATOM   5000 C C   . SER C 3 211 ? 11.08899 -7.21759  -32.98762 1.000 123.42634 ? 261 SER E C   1 
ATOM   5001 O O   . SER C 3 211 ? 10.61423 -6.07922  -32.94800 1.000 135.53742 ? 261 SER E O   1 
ATOM   5002 C CB  . SER C 3 211 ? 9.43297  -9.05390  -32.58998 1.000 115.87650 ? 261 SER E CB  1 
ATOM   5003 O OG  . SER C 3 211 ? 9.09543  -10.16612 -31.77963 1.000 127.28828 ? 261 SER E OG  1 
ATOM   5004 N N   . ARG C 3 212 ? 12.01526 -7.58926  -33.86494 1.000 137.47489 ? 262 ARG E N   1 
ATOM   5005 C CA  . ARG C 3 212 ? 12.61840 -6.66981  -34.82132 1.000 145.56819 ? 262 ARG E CA  1 
ATOM   5006 C C   . ARG C 3 212 ? 12.29364 -7.07730  -36.25396 1.000 158.22935 ? 262 ARG E C   1 
ATOM   5007 O O   . ARG C 3 212 ? 13.15135 -7.04915  -37.13947 1.000 147.56325 ? 262 ARG E O   1 
ATOM   5008 C CB  . ARG C 3 212 ? 14.12769 -6.58612  -34.60810 1.000 130.26904 ? 262 ARG E CB  1 
ATOM   5009 C CG  . ARG C 3 212 ? 14.78233 -7.92910  -34.33531 1.000 133.47071 ? 262 ARG E CG  1 
ATOM   5010 C CD  . ARG C 3 212 ? 15.95839 -7.79074  -33.38227 1.000 143.28521 ? 262 ARG E CD  1 
ATOM   5011 N NE  . ARG C 3 212 ? 17.16407 -7.33256  -34.06177 1.000 157.17941 ? 262 ARG E NE  1 
ATOM   5012 C CZ  . ARG C 3 212 ? 18.33586 -7.15366  -33.46752 1.000 147.17235 ? 262 ARG E CZ  1 
ATOM   5013 N NH1 . ARG C 3 212 ? 18.49818 -7.38698  -32.17532 1.000 120.16209 ? 262 ARG E NH1 1 
ATOM   5014 N NH2 . ARG C 3 212 ? 19.37118 -6.73147  -34.18807 1.000 143.17955 ? 262 ARG E NH2 1 
ATOM   5015 N N   . GLY C 3 213 ? 11.04422 -7.46136  -36.49583 1.000 153.54263 ? 263 GLY E N   1 
ATOM   5016 C CA  . GLY C 3 213 ? 10.60985 -7.85731  -37.82267 1.000 140.63676 ? 263 GLY E CA  1 
ATOM   5017 C C   . GLY C 3 213 ? 9.11653  -7.70278  -38.03549 1.000 143.23851 ? 263 GLY E C   1 
ATOM   5018 O O   . GLY C 3 213 ? 8.67817  -7.02373  -38.96434 1.000 150.02070 ? 263 GLY E O   1 
HETATM 5019 C C1  . NAG D 4 .   ? 8.21812  19.09392  -19.56858 1.000 215.25205 ? 301 NAG E C1  1 
HETATM 5020 C C2  . NAG D 4 .   ? 8.47604  20.44394  -20.23431 1.000 218.64402 ? 301 NAG E C2  1 
HETATM 5021 C C3  . NAG D 4 .   ? 7.50872  21.48821  -19.68532 1.000 221.27181 ? 301 NAG E C3  1 
HETATM 5022 C C4  . NAG D 4 .   ? 6.07028  21.00092  -19.81245 1.000 225.16989 ? 301 NAG E C4  1 
HETATM 5023 C C5  . NAG D 4 .   ? 5.91445  19.60855  -19.20179 1.000 219.80287 ? 301 NAG E C5  1 
HETATM 5024 C C6  . NAG D 4 .   ? 4.54233  19.01529  -19.42295 1.000 211.38345 ? 301 NAG E C6  1 
HETATM 5025 C C7  . NAG D 4 .   ? 10.57687 21.45314  -21.00435 1.000 202.04672 ? 301 NAG E C7  1 
HETATM 5026 C C8  . NAG D 4 .   ? 11.98124 21.82585  -20.63536 1.000 175.87845 ? 301 NAG E C8  1 
HETATM 5027 N N2  . NAG D 4 .   ? 9.85343  20.86916  -20.04320 1.000 214.44379 ? 301 NAG E N2  1 
HETATM 5028 O O3  . NAG D 4 .   ? 7.67389  22.71078  -20.39461 1.000 225.39100 ? 301 NAG E O3  1 
HETATM 5029 O O4  . NAG D 4 .   ? 5.19398  21.90180  -19.14490 1.000 229.09158 ? 301 NAG E O4  1 
HETATM 5030 O O5  . NAG D 4 .   ? 6.85954  18.70154  -19.79027 1.000 215.66729 ? 301 NAG E O5  1 
HETATM 5031 O O6  . NAG D 4 .   ? 4.57984  17.59493  -19.40419 1.000 201.86926 ? 301 NAG E O6  1 
HETATM 5032 O O7  . NAG D 4 .   ? 10.11800 21.67154  -22.12122 1.000 202.31769 ? 301 NAG E O7  1 
# 
