data_9AVH
# 
_entry.id   9AVH 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.401 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9AVH         pdb_00009avh 10.2210/pdb9avh/pdb 
WWPDB D_1000280386 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-01-22 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9AVH 
_pdbx_database_status.recvd_initial_deposition_date   2024-03-03 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
2 mmartine@unizar.es   Marta    Martinez-Julvez ? 'principal investigator/group leader' 0000-0001-9047-0046 
3 ferreira@unizar.es   Patricia Ferreira        ? 'principal investigator/group leader' 0000-0003-4076-6118 
4 mangasjuan@uniovi.es Juan     Mangas-Sanchez  ? 'principal investigator/group leader' 0000-0002-3364-1512 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Martinez-Julvez, M.' 1 0000-0001-9047-0046 
'Ferreira, P.'        2 0000-0003-4076-6118 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Front Bioeng Biotechnol' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2296-4185 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            12 
_citation.language                  ? 
_citation.page_first                1440598 
_citation.page_last                 1440598 
_citation.title                     'Unveiling the kinetic versatility of aryl-alcohol oxidases with different electron acceptors.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.3389/fbioe.2024.1440598 
_citation.pdbx_database_id_PubMed   39161354 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Serrano, A.'          1 ? 
primary 'Cinca-Fernando, P.'   2 ? 
primary 'Carro, J.'            3 ? 
primary 'Velazquez-Campoy, A.' 4 ? 
primary 'Martinez-Julvez, M.'  5 ? 
primary 'Martinez, A.T.'       6 ? 
primary 'Ferreira, P.'         7 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Aryl Alcohol Oxidase'        62808.590 1   1.1.3.7 ? ? ? 
2 non-polymer syn 'FLAVIN-ADENINE DINUCLEOTIDE' 785.550   1   ?       ? ? ? 
3 non-polymer syn '4-METHOXYBENZOIC ACID'       152.147   1   ?       ? ? ? 
4 non-polymer syn GLYCEROL                      92.094    5   ?       ? ? ? 
5 non-polymer syn 'SULFATE ION'                 96.063    6   ?       ? ? ? 
6 water       nat water                         18.015    366 ?       ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MVTFFTDASQLPATVYDFIVVGAGNAGNVVAARLTEDWKTTVLLIEAGISHEGIDSVAVPGLVLDNLPFSPVMWNYTTVP
QAALDNRPIPYAKGRVVGGSSSVNFMEYTRSSNTEYDRWANLTGDAGWSWKNMEQYYLKNSRLVPPQDGHNTTGDVDPSV
HGYGPVPLSLVGTPNPLDARMRAATQAPGAEFPFQLDMNGGDMIGFGIVQSTILNGERMHSGKAFLEPAMSRPNLHVLIE
NTVTRLIQTKTTNGLPSFMKVEFARDALSARSVVTATKEVVLSAGSIGTPQILMLSGIGDREELTAIGVNVTVDNPAVGK
HLKDHPIMANYFQVNSNETYDDIFRDRDVSNTFLAQWKQNRTGPMVASPSTGLGFFRLPDNDTIFERFADPSPGEGAGHI
ELILSNQWTPEVQIPPATGSFLTVHAVVVSPASEGTVRLNSTNPFEFPLLDPQLLSSEFDQHTIIHAARLARQFVSSSPW
ADFVESRTGIIGDTDDDEADLLAAARQATVTIWHPMCTARMAPKGSTDGAIDPDLLVKGVSGLRVIDGAALPAIPATHPM
AAIYLLAERGSDLIKQKWKL
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MVTFFTDASQLPATVYDFIVVGAGNAGNVVAARLTEDWKTTVLLIEAGISHEGIDSVAVPGLVLDNLPFSPVMWNYTTVP
QAALDNRPIPYAKGRVVGGSSSVNFMEYTRSSNTEYDRWANLTGDAGWSWKNMEQYYLKNSRLVPPQDGHNTTGDVDPSV
HGYGPVPLSLVGTPNPLDARMRAATQAPGAEFPFQLDMNGGDMIGFGIVQSTILNGERMHSGKAFLEPAMSRPNLHVLIE
NTVTRLIQTKTTNGLPSFMKVEFARDALSARSVVTATKEVVLSAGSIGTPQILMLSGIGDREELTAIGVNVTVDNPAVGK
HLKDHPIMANYFQVNSNETYDDIFRDRDVSNTFLAQWKQNRTGPMVASPSTGLGFFRLPDNDTIFERFADPSPGEGAGHI
ELILSNQWTPEVQIPPATGSFLTVHAVVVSPASEGTVRLNSTNPFEFPLLDPQLLSSEFDQHTIIHAARLARQFVSSSPW
ADFVESRTGIIGDTDDDEADLLAAARQATVTIWHPMCTARMAPKGSTDGAIDPDLLVKGVSGLRVIDGAALPAIPATHPM
AAIYLLAERGSDLIKQKWKL
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'FLAVIN-ADENINE DINUCLEOTIDE' FAD 
3 '4-METHOXYBENZOIC ACID'       ANN 
4 GLYCEROL                      GOL 
5 'SULFATE ION'                 SO4 
6 water                         HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   VAL n 
1 3   THR n 
1 4   PHE n 
1 5   PHE n 
1 6   THR n 
1 7   ASP n 
1 8   ALA n 
1 9   SER n 
1 10  GLN n 
1 11  LEU n 
1 12  PRO n 
1 13  ALA n 
1 14  THR n 
1 15  VAL n 
1 16  TYR n 
1 17  ASP n 
1 18  PHE n 
1 19  ILE n 
1 20  VAL n 
1 21  VAL n 
1 22  GLY n 
1 23  ALA n 
1 24  GLY n 
1 25  ASN n 
1 26  ALA n 
1 27  GLY n 
1 28  ASN n 
1 29  VAL n 
1 30  VAL n 
1 31  ALA n 
1 32  ALA n 
1 33  ARG n 
1 34  LEU n 
1 35  THR n 
1 36  GLU n 
1 37  ASP n 
1 38  TRP n 
1 39  LYS n 
1 40  THR n 
1 41  THR n 
1 42  VAL n 
1 43  LEU n 
1 44  LEU n 
1 45  ILE n 
1 46  GLU n 
1 47  ALA n 
1 48  GLY n 
1 49  ILE n 
1 50  SER n 
1 51  HIS n 
1 52  GLU n 
1 53  GLY n 
1 54  ILE n 
1 55  ASP n 
1 56  SER n 
1 57  VAL n 
1 58  ALA n 
1 59  VAL n 
1 60  PRO n 
1 61  GLY n 
1 62  LEU n 
1 63  VAL n 
1 64  LEU n 
1 65  ASP n 
1 66  ASN n 
1 67  LEU n 
1 68  PRO n 
1 69  PHE n 
1 70  SER n 
1 71  PRO n 
1 72  VAL n 
1 73  MET n 
1 74  TRP n 
1 75  ASN n 
1 76  TYR n 
1 77  THR n 
1 78  THR n 
1 79  VAL n 
1 80  PRO n 
1 81  GLN n 
1 82  ALA n 
1 83  ALA n 
1 84  LEU n 
1 85  ASP n 
1 86  ASN n 
1 87  ARG n 
1 88  PRO n 
1 89  ILE n 
1 90  PRO n 
1 91  TYR n 
1 92  ALA n 
1 93  LYS n 
1 94  GLY n 
1 95  ARG n 
1 96  VAL n 
1 97  VAL n 
1 98  GLY n 
1 99  GLY n 
1 100 SER n 
1 101 SER n 
1 102 SER n 
1 103 VAL n 
1 104 ASN n 
1 105 PHE n 
1 106 MET n 
1 107 GLU n 
1 108 TYR n 
1 109 THR n 
1 110 ARG n 
1 111 SER n 
1 112 SER n 
1 113 ASN n 
1 114 THR n 
1 115 GLU n 
1 116 TYR n 
1 117 ASP n 
1 118 ARG n 
1 119 TRP n 
1 120 ALA n 
1 121 ASN n 
1 122 LEU n 
1 123 THR n 
1 124 GLY n 
1 125 ASP n 
1 126 ALA n 
1 127 GLY n 
1 128 TRP n 
1 129 SER n 
1 130 TRP n 
1 131 LYS n 
1 132 ASN n 
1 133 MET n 
1 134 GLU n 
1 135 GLN n 
1 136 TYR n 
1 137 TYR n 
1 138 LEU n 
1 139 LYS n 
1 140 ASN n 
1 141 SER n 
1 142 ARG n 
1 143 LEU n 
1 144 VAL n 
1 145 PRO n 
1 146 PRO n 
1 147 GLN n 
1 148 ASP n 
1 149 GLY n 
1 150 HIS n 
1 151 ASN n 
1 152 THR n 
1 153 THR n 
1 154 GLY n 
1 155 ASP n 
1 156 VAL n 
1 157 ASP n 
1 158 PRO n 
1 159 SER n 
1 160 VAL n 
1 161 HIS n 
1 162 GLY n 
1 163 TYR n 
1 164 GLY n 
1 165 PRO n 
1 166 VAL n 
1 167 PRO n 
1 168 LEU n 
1 169 SER n 
1 170 LEU n 
1 171 VAL n 
1 172 GLY n 
1 173 THR n 
1 174 PRO n 
1 175 ASN n 
1 176 PRO n 
1 177 LEU n 
1 178 ASP n 
1 179 ALA n 
1 180 ARG n 
1 181 MET n 
1 182 ARG n 
1 183 ALA n 
1 184 ALA n 
1 185 THR n 
1 186 GLN n 
1 187 ALA n 
1 188 PRO n 
1 189 GLY n 
1 190 ALA n 
1 191 GLU n 
1 192 PHE n 
1 193 PRO n 
1 194 PHE n 
1 195 GLN n 
1 196 LEU n 
1 197 ASP n 
1 198 MET n 
1 199 ASN n 
1 200 GLY n 
1 201 GLY n 
1 202 ASP n 
1 203 MET n 
1 204 ILE n 
1 205 GLY n 
1 206 PHE n 
1 207 GLY n 
1 208 ILE n 
1 209 VAL n 
1 210 GLN n 
1 211 SER n 
1 212 THR n 
1 213 ILE n 
1 214 LEU n 
1 215 ASN n 
1 216 GLY n 
1 217 GLU n 
1 218 ARG n 
1 219 MET n 
1 220 HIS n 
1 221 SER n 
1 222 GLY n 
1 223 LYS n 
1 224 ALA n 
1 225 PHE n 
1 226 LEU n 
1 227 GLU n 
1 228 PRO n 
1 229 ALA n 
1 230 MET n 
1 231 SER n 
1 232 ARG n 
1 233 PRO n 
1 234 ASN n 
1 235 LEU n 
1 236 HIS n 
1 237 VAL n 
1 238 LEU n 
1 239 ILE n 
1 240 GLU n 
1 241 ASN n 
1 242 THR n 
1 243 VAL n 
1 244 THR n 
1 245 ARG n 
1 246 LEU n 
1 247 ILE n 
1 248 GLN n 
1 249 THR n 
1 250 LYS n 
1 251 THR n 
1 252 THR n 
1 253 ASN n 
1 254 GLY n 
1 255 LEU n 
1 256 PRO n 
1 257 SER n 
1 258 PHE n 
1 259 MET n 
1 260 LYS n 
1 261 VAL n 
1 262 GLU n 
1 263 PHE n 
1 264 ALA n 
1 265 ARG n 
1 266 ASP n 
1 267 ALA n 
1 268 LEU n 
1 269 SER n 
1 270 ALA n 
1 271 ARG n 
1 272 SER n 
1 273 VAL n 
1 274 VAL n 
1 275 THR n 
1 276 ALA n 
1 277 THR n 
1 278 LYS n 
1 279 GLU n 
1 280 VAL n 
1 281 VAL n 
1 282 LEU n 
1 283 SER n 
1 284 ALA n 
1 285 GLY n 
1 286 SER n 
1 287 ILE n 
1 288 GLY n 
1 289 THR n 
1 290 PRO n 
1 291 GLN n 
1 292 ILE n 
1 293 LEU n 
1 294 MET n 
1 295 LEU n 
1 296 SER n 
1 297 GLY n 
1 298 ILE n 
1 299 GLY n 
1 300 ASP n 
1 301 ARG n 
1 302 GLU n 
1 303 GLU n 
1 304 LEU n 
1 305 THR n 
1 306 ALA n 
1 307 ILE n 
1 308 GLY n 
1 309 VAL n 
1 310 ASN n 
1 311 VAL n 
1 312 THR n 
1 313 VAL n 
1 314 ASP n 
1 315 ASN n 
1 316 PRO n 
1 317 ALA n 
1 318 VAL n 
1 319 GLY n 
1 320 LYS n 
1 321 HIS n 
1 322 LEU n 
1 323 LYS n 
1 324 ASP n 
1 325 HIS n 
1 326 PRO n 
1 327 ILE n 
1 328 MET n 
1 329 ALA n 
1 330 ASN n 
1 331 TYR n 
1 332 PHE n 
1 333 GLN n 
1 334 VAL n 
1 335 ASN n 
1 336 SER n 
1 337 ASN n 
1 338 GLU n 
1 339 THR n 
1 340 TYR n 
1 341 ASP n 
1 342 ASP n 
1 343 ILE n 
1 344 PHE n 
1 345 ARG n 
1 346 ASP n 
1 347 ARG n 
1 348 ASP n 
1 349 VAL n 
1 350 SER n 
1 351 ASN n 
1 352 THR n 
1 353 PHE n 
1 354 LEU n 
1 355 ALA n 
1 356 GLN n 
1 357 TRP n 
1 358 LYS n 
1 359 GLN n 
1 360 ASN n 
1 361 ARG n 
1 362 THR n 
1 363 GLY n 
1 364 PRO n 
1 365 MET n 
1 366 VAL n 
1 367 ALA n 
1 368 SER n 
1 369 PRO n 
1 370 SER n 
1 371 THR n 
1 372 GLY n 
1 373 LEU n 
1 374 GLY n 
1 375 PHE n 
1 376 PHE n 
1 377 ARG n 
1 378 LEU n 
1 379 PRO n 
1 380 ASP n 
1 381 ASN n 
1 382 ASP n 
1 383 THR n 
1 384 ILE n 
1 385 PHE n 
1 386 GLU n 
1 387 ARG n 
1 388 PHE n 
1 389 ALA n 
1 390 ASP n 
1 391 PRO n 
1 392 SER n 
1 393 PRO n 
1 394 GLY n 
1 395 GLU n 
1 396 GLY n 
1 397 ALA n 
1 398 GLY n 
1 399 HIS n 
1 400 ILE n 
1 401 GLU n 
1 402 LEU n 
1 403 ILE n 
1 404 LEU n 
1 405 SER n 
1 406 ASN n 
1 407 GLN n 
1 408 TRP n 
1 409 THR n 
1 410 PRO n 
1 411 GLU n 
1 412 VAL n 
1 413 GLN n 
1 414 ILE n 
1 415 PRO n 
1 416 PRO n 
1 417 ALA n 
1 418 THR n 
1 419 GLY n 
1 420 SER n 
1 421 PHE n 
1 422 LEU n 
1 423 THR n 
1 424 VAL n 
1 425 HIS n 
1 426 ALA n 
1 427 VAL n 
1 428 VAL n 
1 429 VAL n 
1 430 SER n 
1 431 PRO n 
1 432 ALA n 
1 433 SER n 
1 434 GLU n 
1 435 GLY n 
1 436 THR n 
1 437 VAL n 
1 438 ARG n 
1 439 LEU n 
1 440 ASN n 
1 441 SER n 
1 442 THR n 
1 443 ASN n 
1 444 PRO n 
1 445 PHE n 
1 446 GLU n 
1 447 PHE n 
1 448 PRO n 
1 449 LEU n 
1 450 LEU n 
1 451 ASP n 
1 452 PRO n 
1 453 GLN n 
1 454 LEU n 
1 455 LEU n 
1 456 SER n 
1 457 SER n 
1 458 GLU n 
1 459 PHE n 
1 460 ASP n 
1 461 GLN n 
1 462 HIS n 
1 463 THR n 
1 464 ILE n 
1 465 ILE n 
1 466 HIS n 
1 467 ALA n 
1 468 ALA n 
1 469 ARG n 
1 470 LEU n 
1 471 ALA n 
1 472 ARG n 
1 473 GLN n 
1 474 PHE n 
1 475 VAL n 
1 476 SER n 
1 477 SER n 
1 478 SER n 
1 479 PRO n 
1 480 TRP n 
1 481 ALA n 
1 482 ASP n 
1 483 PHE n 
1 484 VAL n 
1 485 GLU n 
1 486 SER n 
1 487 ARG n 
1 488 THR n 
1 489 GLY n 
1 490 ILE n 
1 491 ILE n 
1 492 GLY n 
1 493 ASP n 
1 494 THR n 
1 495 ASP n 
1 496 ASP n 
1 497 ASP n 
1 498 GLU n 
1 499 ALA n 
1 500 ASP n 
1 501 LEU n 
1 502 LEU n 
1 503 ALA n 
1 504 ALA n 
1 505 ALA n 
1 506 ARG n 
1 507 GLN n 
1 508 ALA n 
1 509 THR n 
1 510 VAL n 
1 511 THR n 
1 512 ILE n 
1 513 TRP n 
1 514 HIS n 
1 515 PRO n 
1 516 MET n 
1 517 CYS n 
1 518 THR n 
1 519 ALA n 
1 520 ARG n 
1 521 MET n 
1 522 ALA n 
1 523 PRO n 
1 524 LYS n 
1 525 GLY n 
1 526 SER n 
1 527 THR n 
1 528 ASP n 
1 529 GLY n 
1 530 ALA n 
1 531 ILE n 
1 532 ASP n 
1 533 PRO n 
1 534 ASP n 
1 535 LEU n 
1 536 LEU n 
1 537 VAL n 
1 538 LYS n 
1 539 GLY n 
1 540 VAL n 
1 541 SER n 
1 542 GLY n 
1 543 LEU n 
1 544 ARG n 
1 545 VAL n 
1 546 ILE n 
1 547 ASP n 
1 548 GLY n 
1 549 ALA n 
1 550 ALA n 
1 551 LEU n 
1 552 PRO n 
1 553 ALA n 
1 554 ILE n 
1 555 PRO n 
1 556 ALA n 
1 557 THR n 
1 558 HIS n 
1 559 PRO n 
1 560 MET n 
1 561 ALA n 
1 562 ALA n 
1 563 ILE n 
1 564 TYR n 
1 565 LEU n 
1 566 LEU n 
1 567 ALA n 
1 568 GLU n 
1 569 ARG n 
1 570 GLY n 
1 571 SER n 
1 572 ASP n 
1 573 LEU n 
1 574 ILE n 
1 575 LYS n 
1 576 GLN n 
1 577 LYS n 
1 578 TRP n 
1 579 LYS n 
1 580 LEU n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   580 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Bjerkandera adusta' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     5331 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                       ?                               'C3 H7 N O2'        89.093  
ANN non-polymer         . '4-METHOXYBENZOIC ACID'       'P-ANISIC ACID'                 'C8 H8 O3'          152.147 
ARG 'L-peptide linking' y ARGININE                      ?                               'C6 H15 N4 O2 1'    175.209 
ASN 'L-peptide linking' y ASPARAGINE                    ?                               'C4 H8 N2 O3'       132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'               ?                               'C4 H7 N O4'        133.103 
CYS 'L-peptide linking' y CYSTEINE                      ?                               'C3 H7 N O2 S'      121.158 
FAD non-polymer         . 'FLAVIN-ADENINE DINUCLEOTIDE' ?                               'C27 H33 N9 O15 P2' 785.550 
GLN 'L-peptide linking' y GLUTAMINE                     ?                               'C5 H10 N2 O3'      146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'               ?                               'C5 H9 N O4'        147.129 
GLY 'peptide linking'   y GLYCINE                       ?                               'C2 H5 N O2'        75.067  
GOL non-polymer         . GLYCEROL                      'GLYCERIN; PROPANE-1,2,3-TRIOL' 'C3 H8 O3'          92.094  
HIS 'L-peptide linking' y HISTIDINE                     ?                               'C6 H10 N3 O2 1'    156.162 
HOH non-polymer         . WATER                         ?                               'H2 O'              18.015  
ILE 'L-peptide linking' y ISOLEUCINE                    ?                               'C6 H13 N O2'       131.173 
LEU 'L-peptide linking' y LEUCINE                       ?                               'C6 H13 N O2'       131.173 
LYS 'L-peptide linking' y LYSINE                        ?                               'C6 H15 N2 O2 1'    147.195 
MET 'L-peptide linking' y METHIONINE                    ?                               'C5 H11 N O2 S'     149.211 
PHE 'L-peptide linking' y PHENYLALANINE                 ?                               'C9 H11 N O2'       165.189 
PRO 'L-peptide linking' y PROLINE                       ?                               'C5 H9 N O2'        115.130 
SER 'L-peptide linking' y SERINE                        ?                               'C3 H7 N O3'        105.093 
SO4 non-polymer         . 'SULFATE ION'                 ?                               'O4 S -2'           96.063  
THR 'L-peptide linking' y THREONINE                     ?                               'C4 H9 N O3'        119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                    ?                               'C11 H12 N2 O2'     204.225 
TYR 'L-peptide linking' y TYROSINE                      ?                               'C9 H11 N O3'       181.189 
VAL 'L-peptide linking' y VALINE                        ?                               'C5 H11 N O2'       117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   0   ?   ?   ?   A . n 
A 1 2   VAL 2   1   ?   ?   ?   A . n 
A 1 3   THR 3   2   2   THR THR A . n 
A 1 4   PHE 4   3   3   PHE PHE A . n 
A 1 5   PHE 5   4   4   PHE PHE A . n 
A 1 6   THR 6   5   5   THR THR A . n 
A 1 7   ASP 7   6   6   ASP ASP A . n 
A 1 8   ALA 8   7   7   ALA ALA A . n 
A 1 9   SER 9   8   8   SER SER A . n 
A 1 10  GLN 10  9   9   GLN GLN A . n 
A 1 11  LEU 11  10  10  LEU LEU A . n 
A 1 12  PRO 12  11  11  PRO PRO A . n 
A 1 13  ALA 13  12  12  ALA ALA A . n 
A 1 14  THR 14  13  13  THR THR A . n 
A 1 15  VAL 15  14  14  VAL VAL A . n 
A 1 16  TYR 16  15  15  TYR TYR A . n 
A 1 17  ASP 17  16  16  ASP ASP A . n 
A 1 18  PHE 18  17  17  PHE PHE A . n 
A 1 19  ILE 19  18  18  ILE ILE A . n 
A 1 20  VAL 20  19  19  VAL VAL A . n 
A 1 21  VAL 21  20  20  VAL VAL A . n 
A 1 22  GLY 22  21  21  GLY GLY A . n 
A 1 23  ALA 23  22  22  ALA ALA A . n 
A 1 24  GLY 24  23  23  GLY GLY A . n 
A 1 25  ASN 25  24  24  ASN ASN A . n 
A 1 26  ALA 26  25  25  ALA ALA A . n 
A 1 27  GLY 27  26  26  GLY GLY A . n 
A 1 28  ASN 28  27  27  ASN ASN A . n 
A 1 29  VAL 29  28  28  VAL VAL A . n 
A 1 30  VAL 30  29  29  VAL VAL A . n 
A 1 31  ALA 31  30  30  ALA ALA A . n 
A 1 32  ALA 32  31  31  ALA ALA A . n 
A 1 33  ARG 33  32  32  ARG ARG A . n 
A 1 34  LEU 34  33  33  LEU LEU A . n 
A 1 35  THR 35  34  34  THR THR A . n 
A 1 36  GLU 36  35  35  GLU GLU A . n 
A 1 37  ASP 37  36  36  ASP ASP A . n 
A 1 38  TRP 38  37  37  TRP TRP A . n 
A 1 39  LYS 39  38  38  LYS LYS A . n 
A 1 40  THR 40  39  39  THR THR A . n 
A 1 41  THR 41  40  40  THR THR A . n 
A 1 42  VAL 42  41  41  VAL VAL A . n 
A 1 43  LEU 43  42  42  LEU LEU A . n 
A 1 44  LEU 44  43  43  LEU LEU A . n 
A 1 45  ILE 45  44  44  ILE ILE A . n 
A 1 46  GLU 46  45  45  GLU GLU A . n 
A 1 47  ALA 47  46  46  ALA ALA A . n 
A 1 48  GLY 48  47  47  GLY GLY A . n 
A 1 49  ILE 49  48  48  ILE ILE A . n 
A 1 50  SER 50  49  49  SER SER A . n 
A 1 51  HIS 51  50  50  HIS HIS A . n 
A 1 52  GLU 52  51  51  GLU GLU A . n 
A 1 53  GLY 53  52  52  GLY GLY A . n 
A 1 54  ILE 54  53  53  ILE ILE A . n 
A 1 55  ASP 55  54  54  ASP ASP A . n 
A 1 56  SER 56  55  55  SER SER A . n 
A 1 57  VAL 57  56  56  VAL VAL A . n 
A 1 58  ALA 58  57  57  ALA ALA A . n 
A 1 59  VAL 59  58  58  VAL VAL A . n 
A 1 60  PRO 60  59  59  PRO PRO A . n 
A 1 61  GLY 61  60  60  GLY GLY A . n 
A 1 62  LEU 62  61  61  LEU LEU A . n 
A 1 63  VAL 63  62  62  VAL VAL A . n 
A 1 64  LEU 64  63  63  LEU LEU A . n 
A 1 65  ASP 65  64  64  ASP ASP A . n 
A 1 66  ASN 66  65  65  ASN ASN A . n 
A 1 67  LEU 67  66  66  LEU LEU A . n 
A 1 68  PRO 68  67  67  PRO PRO A . n 
A 1 69  PHE 69  68  68  PHE PHE A . n 
A 1 70  SER 70  69  69  SER SER A . n 
A 1 71  PRO 71  70  70  PRO PRO A . n 
A 1 72  VAL 72  71  71  VAL VAL A . n 
A 1 73  MET 73  72  72  MET MET A . n 
A 1 74  TRP 74  73  73  TRP TRP A . n 
A 1 75  ASN 75  74  74  ASN ASN A . n 
A 1 76  TYR 76  75  75  TYR TYR A . n 
A 1 77  THR 77  76  76  THR THR A . n 
A 1 78  THR 78  77  77  THR THR A . n 
A 1 79  VAL 79  78  78  VAL VAL A . n 
A 1 80  PRO 80  79  79  PRO PRO A . n 
A 1 81  GLN 81  80  80  GLN GLN A . n 
A 1 82  ALA 82  81  81  ALA ALA A . n 
A 1 83  ALA 83  82  82  ALA ALA A . n 
A 1 84  LEU 84  83  83  LEU LEU A . n 
A 1 85  ASP 85  84  84  ASP ASP A . n 
A 1 86  ASN 86  85  85  ASN ASN A . n 
A 1 87  ARG 87  86  86  ARG ARG A . n 
A 1 88  PRO 88  87  87  PRO PRO A . n 
A 1 89  ILE 89  88  88  ILE ILE A . n 
A 1 90  PRO 90  89  89  PRO PRO A . n 
A 1 91  TYR 91  90  90  TYR TYR A . n 
A 1 92  ALA 92  91  91  ALA ALA A . n 
A 1 93  LYS 93  92  92  LYS LYS A . n 
A 1 94  GLY 94  93  93  GLY GLY A . n 
A 1 95  ARG 95  94  94  ARG ARG A . n 
A 1 96  VAL 96  95  95  VAL VAL A . n 
A 1 97  VAL 97  96  96  VAL VAL A . n 
A 1 98  GLY 98  97  97  GLY GLY A . n 
A 1 99  GLY 99  98  98  GLY GLY A . n 
A 1 100 SER 100 99  99  SER SER A . n 
A 1 101 SER 101 100 100 SER SER A . n 
A 1 102 SER 102 101 101 SER SER A . n 
A 1 103 VAL 103 102 102 VAL VAL A . n 
A 1 104 ASN 104 103 103 ASN ASN A . n 
A 1 105 PHE 105 104 104 PHE PHE A . n 
A 1 106 MET 106 105 105 MET MET A . n 
A 1 107 GLU 107 106 106 GLU GLU A . n 
A 1 108 TYR 108 107 107 TYR TYR A . n 
A 1 109 THR 109 108 108 THR THR A . n 
A 1 110 ARG 110 109 109 ARG ARG A . n 
A 1 111 SER 111 110 110 SER SER A . n 
A 1 112 SER 112 111 111 SER SER A . n 
A 1 113 ASN 113 112 112 ASN ASN A . n 
A 1 114 THR 114 113 113 THR THR A . n 
A 1 115 GLU 115 114 114 GLU GLU A . n 
A 1 116 TYR 116 115 115 TYR TYR A . n 
A 1 117 ASP 117 116 116 ASP ASP A . n 
A 1 118 ARG 118 117 117 ARG ARG A . n 
A 1 119 TRP 119 118 118 TRP TRP A . n 
A 1 120 ALA 120 119 119 ALA ALA A . n 
A 1 121 ASN 121 120 120 ASN ASN A . n 
A 1 122 LEU 122 121 121 LEU LEU A . n 
A 1 123 THR 123 122 122 THR THR A . n 
A 1 124 GLY 124 123 123 GLY GLY A . n 
A 1 125 ASP 125 124 124 ASP ASP A . n 
A 1 126 ALA 126 125 125 ALA ALA A . n 
A 1 127 GLY 127 126 126 GLY GLY A . n 
A 1 128 TRP 128 127 127 TRP TRP A . n 
A 1 129 SER 129 128 128 SER SER A . n 
A 1 130 TRP 130 129 129 TRP TRP A . n 
A 1 131 LYS 131 130 130 LYS LYS A . n 
A 1 132 ASN 132 131 131 ASN ASN A . n 
A 1 133 MET 133 132 132 MET MET A . n 
A 1 134 GLU 134 133 133 GLU GLU A . n 
A 1 135 GLN 135 134 134 GLN GLN A . n 
A 1 136 TYR 136 135 135 TYR TYR A . n 
A 1 137 TYR 137 136 136 TYR TYR A . n 
A 1 138 LEU 138 137 137 LEU LEU A . n 
A 1 139 LYS 139 138 138 LYS LYS A . n 
A 1 140 ASN 140 139 139 ASN ASN A . n 
A 1 141 SER 141 140 140 SER SER A . n 
A 1 142 ARG 142 141 141 ARG ARG A . n 
A 1 143 LEU 143 142 142 LEU LEU A . n 
A 1 144 VAL 144 143 143 VAL VAL A . n 
A 1 145 PRO 145 144 144 PRO PRO A . n 
A 1 146 PRO 146 145 145 PRO PRO A . n 
A 1 147 GLN 147 146 146 GLN GLN A . n 
A 1 148 ASP 148 147 147 ASP ASP A . n 
A 1 149 GLY 149 148 148 GLY GLY A . n 
A 1 150 HIS 150 149 149 HIS HIS A . n 
A 1 151 ASN 151 150 150 ASN ASN A . n 
A 1 152 THR 152 151 151 THR THR A . n 
A 1 153 THR 153 152 152 THR THR A . n 
A 1 154 GLY 154 153 153 GLY GLY A . n 
A 1 155 ASP 155 154 154 ASP ASP A . n 
A 1 156 VAL 156 155 155 VAL VAL A . n 
A 1 157 ASP 157 156 156 ASP ASP A . n 
A 1 158 PRO 158 157 157 PRO PRO A . n 
A 1 159 SER 159 158 158 SER SER A . n 
A 1 160 VAL 160 159 159 VAL VAL A . n 
A 1 161 HIS 161 160 160 HIS HIS A . n 
A 1 162 GLY 162 161 161 GLY GLY A . n 
A 1 163 TYR 163 162 162 TYR TYR A . n 
A 1 164 GLY 164 163 163 GLY GLY A . n 
A 1 165 PRO 165 164 164 PRO PRO A . n 
A 1 166 VAL 166 165 165 VAL VAL A . n 
A 1 167 PRO 167 166 166 PRO PRO A . n 
A 1 168 LEU 168 167 167 LEU LEU A . n 
A 1 169 SER 169 168 168 SER SER A . n 
A 1 170 LEU 170 169 169 LEU LEU A . n 
A 1 171 VAL 171 170 170 VAL VAL A . n 
A 1 172 GLY 172 171 171 GLY GLY A . n 
A 1 173 THR 173 172 172 THR THR A . n 
A 1 174 PRO 174 173 173 PRO PRO A . n 
A 1 175 ASN 175 174 174 ASN ASN A . n 
A 1 176 PRO 176 175 175 PRO PRO A . n 
A 1 177 LEU 177 176 176 LEU LEU A . n 
A 1 178 ASP 178 177 177 ASP ASP A . n 
A 1 179 ALA 179 178 178 ALA ALA A . n 
A 1 180 ARG 180 179 179 ARG ARG A . n 
A 1 181 MET 181 180 180 MET MET A . n 
A 1 182 ARG 182 181 181 ARG ARG A . n 
A 1 183 ALA 183 182 182 ALA ALA A . n 
A 1 184 ALA 184 183 183 ALA ALA A . n 
A 1 185 THR 185 184 184 THR THR A . n 
A 1 186 GLN 186 185 185 GLN GLN A . n 
A 1 187 ALA 187 186 186 ALA ALA A . n 
A 1 188 PRO 188 187 187 PRO PRO A . n 
A 1 189 GLY 189 188 188 GLY GLY A . n 
A 1 190 ALA 190 189 189 ALA ALA A . n 
A 1 191 GLU 191 190 190 GLU GLU A . n 
A 1 192 PHE 192 191 191 PHE PHE A . n 
A 1 193 PRO 193 192 192 PRO PRO A . n 
A 1 194 PHE 194 193 193 PHE PHE A . n 
A 1 195 GLN 195 194 194 GLN GLN A . n 
A 1 196 LEU 196 195 195 LEU LEU A . n 
A 1 197 ASP 197 196 196 ASP ASP A . n 
A 1 198 MET 198 197 197 MET MET A . n 
A 1 199 ASN 199 198 198 ASN ASN A . n 
A 1 200 GLY 200 199 199 GLY GLY A . n 
A 1 201 GLY 201 200 200 GLY GLY A . n 
A 1 202 ASP 202 201 201 ASP ASP A . n 
A 1 203 MET 203 202 202 MET MET A . n 
A 1 204 ILE 204 203 203 ILE ILE A . n 
A 1 205 GLY 205 204 204 GLY GLY A . n 
A 1 206 PHE 206 205 205 PHE PHE A . n 
A 1 207 GLY 207 206 206 GLY GLY A . n 
A 1 208 ILE 208 207 207 ILE ILE A . n 
A 1 209 VAL 209 208 208 VAL VAL A . n 
A 1 210 GLN 210 209 209 GLN GLN A . n 
A 1 211 SER 211 210 210 SER SER A . n 
A 1 212 THR 212 211 211 THR THR A . n 
A 1 213 ILE 213 212 212 ILE ILE A . n 
A 1 214 LEU 214 213 213 LEU LEU A . n 
A 1 215 ASN 215 214 214 ASN ASN A . n 
A 1 216 GLY 216 215 215 GLY GLY A . n 
A 1 217 GLU 217 216 216 GLU GLU A . n 
A 1 218 ARG 218 217 217 ARG ARG A . n 
A 1 219 MET 219 218 218 MET MET A . n 
A 1 220 HIS 220 219 219 HIS HIS A . n 
A 1 221 SER 221 220 220 SER SER A . n 
A 1 222 GLY 222 221 221 GLY GLY A . n 
A 1 223 LYS 223 222 222 LYS LYS A . n 
A 1 224 ALA 224 223 223 ALA ALA A . n 
A 1 225 PHE 225 224 224 PHE PHE A . n 
A 1 226 LEU 226 225 225 LEU LEU A . n 
A 1 227 GLU 227 226 226 GLU GLU A . n 
A 1 228 PRO 228 227 227 PRO PRO A . n 
A 1 229 ALA 229 228 228 ALA ALA A . n 
A 1 230 MET 230 229 229 MET MET A . n 
A 1 231 SER 231 230 230 SER SER A . n 
A 1 232 ARG 232 231 231 ARG ARG A . n 
A 1 233 PRO 233 232 232 PRO PRO A . n 
A 1 234 ASN 234 233 233 ASN ASN A . n 
A 1 235 LEU 235 234 234 LEU LEU A . n 
A 1 236 HIS 236 235 235 HIS HIS A . n 
A 1 237 VAL 237 236 236 VAL VAL A . n 
A 1 238 LEU 238 237 237 LEU LEU A . n 
A 1 239 ILE 239 238 238 ILE ILE A . n 
A 1 240 GLU 240 239 239 GLU GLU A . n 
A 1 241 ASN 241 240 240 ASN ASN A . n 
A 1 242 THR 242 241 241 THR THR A . n 
A 1 243 VAL 243 242 242 VAL VAL A . n 
A 1 244 THR 244 243 243 THR THR A . n 
A 1 245 ARG 245 244 244 ARG ARG A . n 
A 1 246 LEU 246 245 245 LEU LEU A . n 
A 1 247 ILE 247 246 246 ILE ILE A . n 
A 1 248 GLN 248 247 247 GLN GLN A . n 
A 1 249 THR 249 248 248 THR THR A . n 
A 1 250 LYS 250 249 249 LYS LYS A . n 
A 1 251 THR 251 250 250 THR THR A . n 
A 1 252 THR 252 251 251 THR THR A . n 
A 1 253 ASN 253 252 252 ASN ASN A . n 
A 1 254 GLY 254 253 253 GLY GLY A . n 
A 1 255 LEU 255 254 254 LEU LEU A . n 
A 1 256 PRO 256 255 255 PRO PRO A . n 
A 1 257 SER 257 256 256 SER SER A . n 
A 1 258 PHE 258 257 257 PHE PHE A . n 
A 1 259 MET 259 258 258 MET MET A . n 
A 1 260 LYS 260 259 259 LYS LYS A . n 
A 1 261 VAL 261 260 260 VAL VAL A . n 
A 1 262 GLU 262 261 261 GLU GLU A . n 
A 1 263 PHE 263 262 262 PHE PHE A . n 
A 1 264 ALA 264 263 263 ALA ALA A . n 
A 1 265 ARG 265 264 264 ARG ARG A . n 
A 1 266 ASP 266 265 265 ASP ASP A . n 
A 1 267 ALA 267 266 266 ALA ALA A . n 
A 1 268 LEU 268 267 267 LEU LEU A . n 
A 1 269 SER 269 268 268 SER SER A . n 
A 1 270 ALA 270 269 269 ALA ALA A . n 
A 1 271 ARG 271 270 270 ARG ARG A . n 
A 1 272 SER 272 271 271 SER SER A . n 
A 1 273 VAL 273 272 272 VAL VAL A . n 
A 1 274 VAL 274 273 273 VAL VAL A . n 
A 1 275 THR 275 274 274 THR THR A . n 
A 1 276 ALA 276 275 275 ALA ALA A . n 
A 1 277 THR 277 276 276 THR THR A . n 
A 1 278 LYS 278 277 277 LYS LYS A . n 
A 1 279 GLU 279 278 278 GLU GLU A . n 
A 1 280 VAL 280 279 279 VAL VAL A . n 
A 1 281 VAL 281 280 280 VAL VAL A . n 
A 1 282 LEU 282 281 281 LEU LEU A . n 
A 1 283 SER 283 282 282 SER SER A . n 
A 1 284 ALA 284 283 283 ALA ALA A . n 
A 1 285 GLY 285 284 284 GLY GLY A . n 
A 1 286 SER 286 285 285 SER SER A . n 
A 1 287 ILE 287 286 286 ILE ILE A . n 
A 1 288 GLY 288 287 287 GLY GLY A . n 
A 1 289 THR 289 288 288 THR THR A . n 
A 1 290 PRO 290 289 289 PRO PRO A . n 
A 1 291 GLN 291 290 290 GLN GLN A . n 
A 1 292 ILE 292 291 291 ILE ILE A . n 
A 1 293 LEU 293 292 292 LEU LEU A . n 
A 1 294 MET 294 293 293 MET MET A . n 
A 1 295 LEU 295 294 294 LEU LEU A . n 
A 1 296 SER 296 295 295 SER SER A . n 
A 1 297 GLY 297 296 296 GLY GLY A . n 
A 1 298 ILE 298 297 297 ILE ILE A . n 
A 1 299 GLY 299 298 298 GLY GLY A . n 
A 1 300 ASP 300 299 299 ASP ASP A . n 
A 1 301 ARG 301 300 300 ARG ARG A . n 
A 1 302 GLU 302 301 301 GLU GLU A . n 
A 1 303 GLU 303 302 302 GLU GLU A . n 
A 1 304 LEU 304 303 303 LEU LEU A . n 
A 1 305 THR 305 304 304 THR THR A . n 
A 1 306 ALA 306 305 305 ALA ALA A . n 
A 1 307 ILE 307 306 306 ILE ILE A . n 
A 1 308 GLY 308 307 307 GLY GLY A . n 
A 1 309 VAL 309 308 308 VAL VAL A . n 
A 1 310 ASN 310 309 309 ASN ASN A . n 
A 1 311 VAL 311 310 310 VAL VAL A . n 
A 1 312 THR 312 311 311 THR THR A . n 
A 1 313 VAL 313 312 312 VAL VAL A . n 
A 1 314 ASP 314 313 313 ASP ASP A . n 
A 1 315 ASN 315 314 314 ASN ASN A . n 
A 1 316 PRO 316 315 315 PRO PRO A . n 
A 1 317 ALA 317 316 316 ALA ALA A . n 
A 1 318 VAL 318 317 317 VAL VAL A . n 
A 1 319 GLY 319 318 318 GLY GLY A . n 
A 1 320 LYS 320 319 319 LYS LYS A . n 
A 1 321 HIS 321 320 320 HIS HIS A . n 
A 1 322 LEU 322 321 321 LEU LEU A . n 
A 1 323 LYS 323 322 322 LYS LYS A . n 
A 1 324 ASP 324 323 323 ASP ASP A . n 
A 1 325 HIS 325 324 324 HIS HIS A . n 
A 1 326 PRO 326 325 325 PRO PRO A . n 
A 1 327 ILE 327 326 326 ILE ILE A . n 
A 1 328 MET 328 327 327 MET MET A . n 
A 1 329 ALA 329 328 328 ALA ALA A . n 
A 1 330 ASN 330 329 329 ASN ASN A . n 
A 1 331 TYR 331 330 330 TYR TYR A . n 
A 1 332 PHE 332 331 331 PHE PHE A . n 
A 1 333 GLN 333 332 332 GLN GLN A . n 
A 1 334 VAL 334 333 333 VAL VAL A . n 
A 1 335 ASN 335 334 334 ASN ASN A . n 
A 1 336 SER 336 335 335 SER SER A . n 
A 1 337 ASN 337 336 336 ASN ASN A . n 
A 1 338 GLU 338 337 337 GLU GLU A . n 
A 1 339 THR 339 338 338 THR THR A . n 
A 1 340 TYR 340 339 339 TYR TYR A . n 
A 1 341 ASP 341 340 340 ASP ASP A . n 
A 1 342 ASP 342 341 341 ASP ASP A . n 
A 1 343 ILE 343 342 342 ILE ILE A . n 
A 1 344 PHE 344 343 343 PHE PHE A . n 
A 1 345 ARG 345 344 344 ARG ARG A . n 
A 1 346 ASP 346 345 345 ASP ASP A . n 
A 1 347 ARG 347 346 346 ARG ARG A . n 
A 1 348 ASP 348 347 347 ASP ASP A . n 
A 1 349 VAL 349 348 348 VAL VAL A . n 
A 1 350 SER 350 349 349 SER SER A . n 
A 1 351 ASN 351 350 350 ASN ASN A . n 
A 1 352 THR 352 351 351 THR THR A . n 
A 1 353 PHE 353 352 352 PHE PHE A . n 
A 1 354 LEU 354 353 353 LEU LEU A . n 
A 1 355 ALA 355 354 354 ALA ALA A . n 
A 1 356 GLN 356 355 355 GLN GLN A . n 
A 1 357 TRP 357 356 356 TRP TRP A . n 
A 1 358 LYS 358 357 357 LYS LYS A . n 
A 1 359 GLN 359 358 358 GLN GLN A . n 
A 1 360 ASN 360 359 359 ASN ASN A . n 
A 1 361 ARG 361 360 360 ARG ARG A . n 
A 1 362 THR 362 361 361 THR THR A . n 
A 1 363 GLY 363 362 362 GLY GLY A . n 
A 1 364 PRO 364 363 363 PRO PRO A . n 
A 1 365 MET 365 364 364 MET MET A . n 
A 1 366 VAL 366 365 365 VAL VAL A . n 
A 1 367 ALA 367 366 366 ALA ALA A . n 
A 1 368 SER 368 367 367 SER SER A . n 
A 1 369 PRO 369 368 368 PRO PRO A . n 
A 1 370 SER 370 369 369 SER SER A . n 
A 1 371 THR 371 370 370 THR THR A . n 
A 1 372 GLY 372 371 371 GLY GLY A . n 
A 1 373 LEU 373 372 372 LEU LEU A . n 
A 1 374 GLY 374 373 373 GLY GLY A . n 
A 1 375 PHE 375 374 374 PHE PHE A . n 
A 1 376 PHE 376 375 375 PHE PHE A . n 
A 1 377 ARG 377 376 376 ARG ARG A . n 
A 1 378 LEU 378 377 377 LEU LEU A . n 
A 1 379 PRO 379 378 378 PRO PRO A . n 
A 1 380 ASP 380 379 379 ASP ASP A . n 
A 1 381 ASN 381 380 380 ASN ASN A . n 
A 1 382 ASP 382 381 381 ASP ASP A . n 
A 1 383 THR 383 382 382 THR THR A . n 
A 1 384 ILE 384 383 383 ILE ILE A . n 
A 1 385 PHE 385 384 384 PHE PHE A . n 
A 1 386 GLU 386 385 385 GLU GLU A . n 
A 1 387 ARG 387 386 386 ARG ARG A . n 
A 1 388 PHE 388 387 387 PHE PHE A . n 
A 1 389 ALA 389 388 388 ALA ALA A . n 
A 1 390 ASP 390 389 389 ASP ASP A . n 
A 1 391 PRO 391 390 390 PRO PRO A . n 
A 1 392 SER 392 391 391 SER SER A . n 
A 1 393 PRO 393 392 392 PRO PRO A . n 
A 1 394 GLY 394 393 393 GLY GLY A . n 
A 1 395 GLU 395 394 394 GLU GLU A . n 
A 1 396 GLY 396 395 395 GLY GLY A . n 
A 1 397 ALA 397 396 396 ALA ALA A . n 
A 1 398 GLY 398 397 397 GLY GLY A . n 
A 1 399 HIS 399 398 398 HIS HIS A . n 
A 1 400 ILE 400 399 399 ILE ILE A . n 
A 1 401 GLU 401 400 400 GLU GLU A . n 
A 1 402 LEU 402 401 401 LEU LEU A . n 
A 1 403 ILE 403 402 402 ILE ILE A . n 
A 1 404 LEU 404 403 403 LEU LEU A . n 
A 1 405 SER 405 404 404 SER SER A . n 
A 1 406 ASN 406 405 405 ASN ASN A . n 
A 1 407 GLN 407 406 406 GLN GLN A . n 
A 1 408 TRP 408 407 407 TRP TRP A . n 
A 1 409 THR 409 408 408 THR THR A . n 
A 1 410 PRO 410 409 409 PRO PRO A . n 
A 1 411 GLU 411 410 410 GLU GLU A . n 
A 1 412 VAL 412 411 411 VAL VAL A . n 
A 1 413 GLN 413 412 412 GLN GLN A . n 
A 1 414 ILE 414 413 413 ILE ILE A . n 
A 1 415 PRO 415 414 414 PRO PRO A . n 
A 1 416 PRO 416 415 415 PRO PRO A . n 
A 1 417 ALA 417 416 416 ALA ALA A . n 
A 1 418 THR 418 417 417 THR THR A . n 
A 1 419 GLY 419 418 418 GLY GLY A . n 
A 1 420 SER 420 419 419 SER SER A . n 
A 1 421 PHE 421 420 420 PHE PHE A . n 
A 1 422 LEU 422 421 421 LEU LEU A . n 
A 1 423 THR 423 422 422 THR THR A . n 
A 1 424 VAL 424 423 423 VAL VAL A . n 
A 1 425 HIS 425 424 424 HIS HIS A . n 
A 1 426 ALA 426 425 425 ALA ALA A . n 
A 1 427 VAL 427 426 426 VAL VAL A . n 
A 1 428 VAL 428 427 427 VAL VAL A . n 
A 1 429 VAL 429 428 428 VAL VAL A . n 
A 1 430 SER 430 429 429 SER SER A . n 
A 1 431 PRO 431 430 430 PRO PRO A . n 
A 1 432 ALA 432 431 431 ALA ALA A . n 
A 1 433 SER 433 432 432 SER SER A . n 
A 1 434 GLU 434 433 433 GLU GLU A . n 
A 1 435 GLY 435 434 434 GLY GLY A . n 
A 1 436 THR 436 435 435 THR THR A . n 
A 1 437 VAL 437 436 436 VAL VAL A . n 
A 1 438 ARG 438 437 437 ARG ARG A . n 
A 1 439 LEU 439 438 438 LEU LEU A . n 
A 1 440 ASN 440 439 439 ASN ASN A . n 
A 1 441 SER 441 440 440 SER SER A . n 
A 1 442 THR 442 441 441 THR THR A . n 
A 1 443 ASN 443 442 442 ASN ASN A . n 
A 1 444 PRO 444 443 443 PRO PRO A . n 
A 1 445 PHE 445 444 444 PHE PHE A . n 
A 1 446 GLU 446 445 445 GLU GLU A . n 
A 1 447 PHE 447 446 446 PHE PHE A . n 
A 1 448 PRO 448 447 447 PRO PRO A . n 
A 1 449 LEU 449 448 448 LEU LEU A . n 
A 1 450 LEU 450 449 449 LEU LEU A . n 
A 1 451 ASP 451 450 450 ASP ASP A . n 
A 1 452 PRO 452 451 451 PRO PRO A . n 
A 1 453 GLN 453 452 452 GLN GLN A . n 
A 1 454 LEU 454 453 453 LEU LEU A . n 
A 1 455 LEU 455 454 454 LEU LEU A . n 
A 1 456 SER 456 455 455 SER SER A . n 
A 1 457 SER 457 456 456 SER SER A . n 
A 1 458 GLU 458 457 457 GLU GLU A . n 
A 1 459 PHE 459 458 458 PHE PHE A . n 
A 1 460 ASP 460 459 459 ASP ASP A . n 
A 1 461 GLN 461 460 460 GLN GLN A . n 
A 1 462 HIS 462 461 461 HIS HIS A . n 
A 1 463 THR 463 462 462 THR THR A . n 
A 1 464 ILE 464 463 463 ILE ILE A . n 
A 1 465 ILE 465 464 464 ILE ILE A . n 
A 1 466 HIS 466 465 465 HIS HIS A . n 
A 1 467 ALA 467 466 466 ALA ALA A . n 
A 1 468 ALA 468 467 467 ALA ALA A . n 
A 1 469 ARG 469 468 468 ARG ARG A . n 
A 1 470 LEU 470 469 469 LEU LEU A . n 
A 1 471 ALA 471 470 470 ALA ALA A . n 
A 1 472 ARG 472 471 471 ARG ARG A . n 
A 1 473 GLN 473 472 472 GLN GLN A . n 
A 1 474 PHE 474 473 473 PHE PHE A . n 
A 1 475 VAL 475 474 474 VAL VAL A . n 
A 1 476 SER 476 475 475 SER SER A . n 
A 1 477 SER 477 476 476 SER SER A . n 
A 1 478 SER 478 477 477 SER SER A . n 
A 1 479 PRO 479 478 478 PRO PRO A . n 
A 1 480 TRP 480 479 479 TRP TRP A . n 
A 1 481 ALA 481 480 480 ALA ALA A . n 
A 1 482 ASP 482 481 481 ASP ASP A . n 
A 1 483 PHE 483 482 482 PHE PHE A . n 
A 1 484 VAL 484 483 483 VAL VAL A . n 
A 1 485 GLU 485 484 484 GLU GLU A . n 
A 1 486 SER 486 485 485 SER SER A . n 
A 1 487 ARG 487 486 486 ARG ARG A . n 
A 1 488 THR 488 487 487 THR THR A . n 
A 1 489 GLY 489 488 488 GLY GLY A . n 
A 1 490 ILE 490 489 489 ILE ILE A . n 
A 1 491 ILE 491 490 490 ILE ILE A . n 
A 1 492 GLY 492 491 491 GLY GLY A . n 
A 1 493 ASP 493 492 492 ASP ASP A . n 
A 1 494 THR 494 493 493 THR THR A . n 
A 1 495 ASP 495 494 494 ASP ASP A . n 
A 1 496 ASP 496 495 495 ASP ASP A . n 
A 1 497 ASP 497 496 496 ASP ASP A . n 
A 1 498 GLU 498 497 497 GLU GLU A . n 
A 1 499 ALA 499 498 498 ALA ALA A . n 
A 1 500 ASP 500 499 499 ASP ASP A . n 
A 1 501 LEU 501 500 500 LEU LEU A . n 
A 1 502 LEU 502 501 501 LEU LEU A . n 
A 1 503 ALA 503 502 502 ALA ALA A . n 
A 1 504 ALA 504 503 503 ALA ALA A . n 
A 1 505 ALA 505 504 504 ALA ALA A . n 
A 1 506 ARG 506 505 505 ARG ARG A . n 
A 1 507 GLN 507 506 506 GLN GLN A . n 
A 1 508 ALA 508 507 507 ALA ALA A . n 
A 1 509 THR 509 508 508 THR THR A . n 
A 1 510 VAL 510 509 509 VAL VAL A . n 
A 1 511 THR 511 510 510 THR THR A . n 
A 1 512 ILE 512 511 511 ILE ILE A . n 
A 1 513 TRP 513 512 512 TRP TRP A . n 
A 1 514 HIS 514 513 513 HIS HIS A . n 
A 1 515 PRO 515 514 514 PRO PRO A . n 
A 1 516 MET 516 515 515 MET MET A . n 
A 1 517 CYS 517 516 516 CYS CYS A . n 
A 1 518 THR 518 517 517 THR THR A . n 
A 1 519 ALA 519 518 518 ALA ALA A . n 
A 1 520 ARG 520 519 519 ARG ARG A . n 
A 1 521 MET 521 520 520 MET MET A . n 
A 1 522 ALA 522 521 521 ALA ALA A . n 
A 1 523 PRO 523 522 522 PRO PRO A . n 
A 1 524 LYS 524 523 523 LYS LYS A . n 
A 1 525 GLY 525 524 524 GLY GLY A . n 
A 1 526 SER 526 525 525 SER SER A . n 
A 1 527 THR 527 526 526 THR THR A . n 
A 1 528 ASP 528 527 527 ASP ASP A . n 
A 1 529 GLY 529 528 528 GLY GLY A . n 
A 1 530 ALA 530 529 529 ALA ALA A . n 
A 1 531 ILE 531 530 530 ILE ILE A . n 
A 1 532 ASP 532 531 531 ASP ASP A . n 
A 1 533 PRO 533 532 532 PRO PRO A . n 
A 1 534 ASP 534 533 533 ASP ASP A . n 
A 1 535 LEU 535 534 534 LEU LEU A . n 
A 1 536 LEU 536 535 535 LEU LEU A . n 
A 1 537 VAL 537 536 536 VAL VAL A . n 
A 1 538 LYS 538 537 537 LYS LYS A . n 
A 1 539 GLY 539 538 538 GLY GLY A . n 
A 1 540 VAL 540 539 539 VAL VAL A . n 
A 1 541 SER 541 540 540 SER SER A . n 
A 1 542 GLY 542 541 541 GLY GLY A . n 
A 1 543 LEU 543 542 542 LEU LEU A . n 
A 1 544 ARG 544 543 543 ARG ARG A . n 
A 1 545 VAL 545 544 544 VAL VAL A . n 
A 1 546 ILE 546 545 545 ILE ILE A . n 
A 1 547 ASP 547 546 546 ASP ASP A . n 
A 1 548 GLY 548 547 547 GLY GLY A . n 
A 1 549 ALA 549 548 548 ALA ALA A . n 
A 1 550 ALA 550 549 549 ALA ALA A . n 
A 1 551 LEU 551 550 550 LEU LEU A . n 
A 1 552 PRO 552 551 551 PRO PRO A . n 
A 1 553 ALA 553 552 552 ALA ALA A . n 
A 1 554 ILE 554 553 553 ILE ILE A . n 
A 1 555 PRO 555 554 554 PRO PRO A . n 
A 1 556 ALA 556 555 555 ALA ALA A . n 
A 1 557 THR 557 556 556 THR THR A . n 
A 1 558 HIS 558 557 557 HIS HIS A . n 
A 1 559 PRO 559 558 558 PRO PRO A . n 
A 1 560 MET 560 559 559 MET MET A . n 
A 1 561 ALA 561 560 560 ALA ALA A . n 
A 1 562 ALA 562 561 561 ALA ALA A . n 
A 1 563 ILE 563 562 562 ILE ILE A . n 
A 1 564 TYR 564 563 563 TYR TYR A . n 
A 1 565 LEU 565 564 564 LEU LEU A . n 
A 1 566 LEU 566 565 565 LEU LEU A . n 
A 1 567 ALA 567 566 566 ALA ALA A . n 
A 1 568 GLU 568 567 567 GLU GLU A . n 
A 1 569 ARG 569 568 568 ARG ARG A . n 
A 1 570 GLY 570 569 569 GLY GLY A . n 
A 1 571 SER 571 570 570 SER SER A . n 
A 1 572 ASP 572 571 571 ASP ASP A . n 
A 1 573 LEU 573 572 572 LEU LEU A . n 
A 1 574 ILE 574 573 573 ILE ILE A . n 
A 1 575 LYS 575 574 574 LYS LYS A . n 
A 1 576 GLN 576 575 575 GLN GLN A . n 
A 1 577 LYS 577 576 576 LYS LYS A . n 
A 1 578 TRP 578 577 577 TRP TRP A . n 
A 1 579 LYS 579 578 578 LYS LYS A . n 
A 1 580 LEU 580 579 579 LEU LEU A . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 ANN ? ? ANN ? ? 'SUBJECT OF INVESTIGATION' ? 
2 FAD ? ? FAD ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 FAD 1   600  600 FAD FAD A . 
C 3 ANN 1   601  601 ANN DRG A . 
D 4 GOL 1   602  602 GOL GOL A . 
E 4 GOL 1   603  603 GOL GOL A . 
F 4 GOL 1   604  604 GOL GOL A . 
G 4 GOL 1   605  605 GOL GOL A . 
H 4 GOL 1   606  606 GOL GOL A . 
I 5 SO4 1   607  607 SO4 SO4 A . 
J 5 SO4 1   608  608 SO4 SO4 A . 
K 5 SO4 1   609  609 SO4 SO4 A . 
L 5 SO4 1   610  610 SO4 SO4 A . 
M 5 SO4 1   611  611 SO4 SO4 A . 
N 5 SO4 1   612  612 SO4 SO4 A . 
O 6 HOH 1   701  365 HOH HOH A . 
O 6 HOH 2   702  181 HOH HOH A . 
O 6 HOH 3   703  332 HOH HOH A . 
O 6 HOH 4   704  257 HOH HOH A . 
O 6 HOH 5   705  321 HOH HOH A . 
O 6 HOH 6   706  323 HOH HOH A . 
O 6 HOH 7   707  359 HOH HOH A . 
O 6 HOH 8   708  268 HOH HOH A . 
O 6 HOH 9   709  215 HOH HOH A . 
O 6 HOH 10  710  81  HOH HOH A . 
O 6 HOH 11  711  343 HOH HOH A . 
O 6 HOH 12  712  263 HOH HOH A . 
O 6 HOH 13  713  286 HOH HOH A . 
O 6 HOH 14  714  155 HOH HOH A . 
O 6 HOH 15  715  231 HOH HOH A . 
O 6 HOH 16  716  194 HOH HOH A . 
O 6 HOH 17  717  270 HOH HOH A . 
O 6 HOH 18  718  65  HOH HOH A . 
O 6 HOH 19  719  67  HOH HOH A . 
O 6 HOH 20  720  362 HOH HOH A . 
O 6 HOH 21  721  208 HOH HOH A . 
O 6 HOH 22  722  251 HOH HOH A . 
O 6 HOH 23  723  223 HOH HOH A . 
O 6 HOH 24  724  233 HOH HOH A . 
O 6 HOH 25  725  185 HOH HOH A . 
O 6 HOH 26  726  283 HOH HOH A . 
O 6 HOH 27  727  77  HOH HOH A . 
O 6 HOH 28  728  200 HOH HOH A . 
O 6 HOH 29  729  366 HOH HOH A . 
O 6 HOH 30  730  158 HOH HOH A . 
O 6 HOH 31  731  325 HOH HOH A . 
O 6 HOH 32  732  202 HOH HOH A . 
O 6 HOH 33  733  182 HOH HOH A . 
O 6 HOH 34  734  255 HOH HOH A . 
O 6 HOH 35  735  70  HOH HOH A . 
O 6 HOH 36  736  175 HOH HOH A . 
O 6 HOH 37  737  237 HOH HOH A . 
O 6 HOH 38  738  100 HOH HOH A . 
O 6 HOH 39  739  25  HOH HOH A . 
O 6 HOH 40  740  19  HOH HOH A . 
O 6 HOH 41  741  178 HOH HOH A . 
O 6 HOH 42  742  14  HOH HOH A . 
O 6 HOH 43  743  73  HOH HOH A . 
O 6 HOH 44  744  118 HOH HOH A . 
O 6 HOH 45  745  75  HOH HOH A . 
O 6 HOH 46  746  12  HOH HOH A . 
O 6 HOH 47  747  144 HOH HOH A . 
O 6 HOH 48  748  78  HOH HOH A . 
O 6 HOH 49  749  69  HOH HOH A . 
O 6 HOH 50  750  22  HOH HOH A . 
O 6 HOH 51  751  254 HOH HOH A . 
O 6 HOH 52  752  120 HOH HOH A . 
O 6 HOH 53  753  284 HOH HOH A . 
O 6 HOH 54  754  1   HOH HOH A . 
O 6 HOH 55  755  152 HOH HOH A . 
O 6 HOH 56  756  191 HOH HOH A . 
O 6 HOH 57  757  33  HOH HOH A . 
O 6 HOH 58  758  171 HOH HOH A . 
O 6 HOH 59  759  109 HOH HOH A . 
O 6 HOH 60  760  36  HOH HOH A . 
O 6 HOH 61  761  271 HOH HOH A . 
O 6 HOH 62  762  43  HOH HOH A . 
O 6 HOH 63  763  205 HOH HOH A . 
O 6 HOH 64  764  20  HOH HOH A . 
O 6 HOH 65  765  299 HOH HOH A . 
O 6 HOH 66  766  247 HOH HOH A . 
O 6 HOH 67  767  124 HOH HOH A . 
O 6 HOH 68  768  213 HOH HOH A . 
O 6 HOH 69  769  153 HOH HOH A . 
O 6 HOH 70  770  217 HOH HOH A . 
O 6 HOH 71  771  92  HOH HOH A . 
O 6 HOH 72  772  292 HOH HOH A . 
O 6 HOH 73  773  85  HOH HOH A . 
O 6 HOH 74  774  148 HOH HOH A . 
O 6 HOH 75  775  116 HOH HOH A . 
O 6 HOH 76  776  351 HOH HOH A . 
O 6 HOH 77  777  6   HOH HOH A . 
O 6 HOH 78  778  47  HOH HOH A . 
O 6 HOH 79  779  128 HOH HOH A . 
O 6 HOH 80  780  236 HOH HOH A . 
O 6 HOH 81  781  222 HOH HOH A . 
O 6 HOH 82  782  108 HOH HOH A . 
O 6 HOH 83  783  314 HOH HOH A . 
O 6 HOH 84  784  89  HOH HOH A . 
O 6 HOH 85  785  240 HOH HOH A . 
O 6 HOH 86  786  26  HOH HOH A . 
O 6 HOH 87  787  4   HOH HOH A . 
O 6 HOH 88  788  157 HOH HOH A . 
O 6 HOH 89  789  76  HOH HOH A . 
O 6 HOH 90  790  21  HOH HOH A . 
O 6 HOH 91  791  74  HOH HOH A . 
O 6 HOH 92  792  29  HOH HOH A . 
O 6 HOH 93  793  68  HOH HOH A . 
O 6 HOH 94  794  46  HOH HOH A . 
O 6 HOH 95  795  219 HOH HOH A . 
O 6 HOH 96  796  18  HOH HOH A . 
O 6 HOH 97  797  244 HOH HOH A . 
O 6 HOH 98  798  346 HOH HOH A . 
O 6 HOH 99  799  352 HOH HOH A . 
O 6 HOH 100 800  9   HOH HOH A . 
O 6 HOH 101 801  42  HOH HOH A . 
O 6 HOH 102 802  166 HOH HOH A . 
O 6 HOH 103 803  130 HOH HOH A . 
O 6 HOH 104 804  281 HOH HOH A . 
O 6 HOH 105 805  235 HOH HOH A . 
O 6 HOH 106 806  113 HOH HOH A . 
O 6 HOH 107 807  52  HOH HOH A . 
O 6 HOH 108 808  260 HOH HOH A . 
O 6 HOH 109 809  121 HOH HOH A . 
O 6 HOH 110 810  37  HOH HOH A . 
O 6 HOH 111 811  212 HOH HOH A . 
O 6 HOH 112 812  102 HOH HOH A . 
O 6 HOH 113 813  88  HOH HOH A . 
O 6 HOH 114 814  50  HOH HOH A . 
O 6 HOH 115 815  266 HOH HOH A . 
O 6 HOH 116 816  27  HOH HOH A . 
O 6 HOH 117 817  318 HOH HOH A . 
O 6 HOH 118 818  86  HOH HOH A . 
O 6 HOH 119 819  63  HOH HOH A . 
O 6 HOH 120 820  96  HOH HOH A . 
O 6 HOH 121 821  98  HOH HOH A . 
O 6 HOH 122 822  51  HOH HOH A . 
O 6 HOH 123 823  11  HOH HOH A . 
O 6 HOH 124 824  162 HOH HOH A . 
O 6 HOH 125 825  264 HOH HOH A . 
O 6 HOH 126 826  177 HOH HOH A . 
O 6 HOH 127 827  13  HOH HOH A . 
O 6 HOH 128 828  31  HOH HOH A . 
O 6 HOH 129 829  57  HOH HOH A . 
O 6 HOH 130 830  44  HOH HOH A . 
O 6 HOH 131 831  41  HOH HOH A . 
O 6 HOH 132 832  140 HOH HOH A . 
O 6 HOH 133 833  220 HOH HOH A . 
O 6 HOH 134 834  198 HOH HOH A . 
O 6 HOH 135 835  192 HOH HOH A . 
O 6 HOH 136 836  285 HOH HOH A . 
O 6 HOH 137 837  295 HOH HOH A . 
O 6 HOH 138 838  60  HOH HOH A . 
O 6 HOH 139 839  103 HOH HOH A . 
O 6 HOH 140 840  2   HOH HOH A . 
O 6 HOH 141 841  315 HOH HOH A . 
O 6 HOH 142 842  167 HOH HOH A . 
O 6 HOH 143 843  38  HOH HOH A . 
O 6 HOH 144 844  117 HOH HOH A . 
O 6 HOH 145 845  319 HOH HOH A . 
O 6 HOH 146 846  126 HOH HOH A . 
O 6 HOH 147 847  34  HOH HOH A . 
O 6 HOH 148 848  99  HOH HOH A . 
O 6 HOH 149 849  348 HOH HOH A . 
O 6 HOH 150 850  97  HOH HOH A . 
O 6 HOH 151 851  293 HOH HOH A . 
O 6 HOH 152 852  17  HOH HOH A . 
O 6 HOH 153 853  94  HOH HOH A . 
O 6 HOH 154 854  168 HOH HOH A . 
O 6 HOH 155 855  170 HOH HOH A . 
O 6 HOH 156 856  210 HOH HOH A . 
O 6 HOH 157 857  110 HOH HOH A . 
O 6 HOH 158 858  278 HOH HOH A . 
O 6 HOH 159 859  8   HOH HOH A . 
O 6 HOH 160 860  344 HOH HOH A . 
O 6 HOH 161 861  320 HOH HOH A . 
O 6 HOH 162 862  135 HOH HOH A . 
O 6 HOH 163 863  188 HOH HOH A . 
O 6 HOH 164 864  211 HOH HOH A . 
O 6 HOH 165 865  101 HOH HOH A . 
O 6 HOH 166 866  7   HOH HOH A . 
O 6 HOH 167 867  252 HOH HOH A . 
O 6 HOH 168 868  201 HOH HOH A . 
O 6 HOH 169 869  23  HOH HOH A . 
O 6 HOH 170 870  35  HOH HOH A . 
O 6 HOH 171 871  326 HOH HOH A . 
O 6 HOH 172 872  179 HOH HOH A . 
O 6 HOH 173 873  317 HOH HOH A . 
O 6 HOH 174 874  241 HOH HOH A . 
O 6 HOH 175 875  145 HOH HOH A . 
O 6 HOH 176 876  137 HOH HOH A . 
O 6 HOH 177 877  161 HOH HOH A . 
O 6 HOH 178 878  62  HOH HOH A . 
O 6 HOH 179 879  143 HOH HOH A . 
O 6 HOH 180 880  154 HOH HOH A . 
O 6 HOH 181 881  230 HOH HOH A . 
O 6 HOH 182 882  150 HOH HOH A . 
O 6 HOH 183 883  330 HOH HOH A . 
O 6 HOH 184 884  209 HOH HOH A . 
O 6 HOH 185 885  296 HOH HOH A . 
O 6 HOH 186 886  104 HOH HOH A . 
O 6 HOH 187 887  48  HOH HOH A . 
O 6 HOH 188 888  123 HOH HOH A . 
O 6 HOH 189 889  10  HOH HOH A . 
O 6 HOH 190 890  272 HOH HOH A . 
O 6 HOH 191 891  301 HOH HOH A . 
O 6 HOH 192 892  95  HOH HOH A . 
O 6 HOH 193 893  122 HOH HOH A . 
O 6 HOH 194 894  338 HOH HOH A . 
O 6 HOH 195 895  349 HOH HOH A . 
O 6 HOH 196 896  93  HOH HOH A . 
O 6 HOH 197 897  142 HOH HOH A . 
O 6 HOH 198 898  239 HOH HOH A . 
O 6 HOH 199 899  134 HOH HOH A . 
O 6 HOH 200 900  232 HOH HOH A . 
O 6 HOH 201 901  16  HOH HOH A . 
O 6 HOH 202 902  298 HOH HOH A . 
O 6 HOH 203 903  172 HOH HOH A . 
O 6 HOH 204 904  249 HOH HOH A . 
O 6 HOH 205 905  341 HOH HOH A . 
O 6 HOH 206 906  147 HOH HOH A . 
O 6 HOH 207 907  139 HOH HOH A . 
O 6 HOH 208 908  133 HOH HOH A . 
O 6 HOH 209 909  119 HOH HOH A . 
O 6 HOH 210 910  176 HOH HOH A . 
O 6 HOH 211 911  190 HOH HOH A . 
O 6 HOH 212 912  131 HOH HOH A . 
O 6 HOH 213 913  24  HOH HOH A . 
O 6 HOH 214 914  64  HOH HOH A . 
O 6 HOH 215 915  273 HOH HOH A . 
O 6 HOH 216 916  90  HOH HOH A . 
O 6 HOH 217 917  72  HOH HOH A . 
O 6 HOH 218 918  53  HOH HOH A . 
O 6 HOH 219 919  39  HOH HOH A . 
O 6 HOH 220 920  61  HOH HOH A . 
O 6 HOH 221 921  28  HOH HOH A . 
O 6 HOH 222 922  141 HOH HOH A . 
O 6 HOH 223 923  316 HOH HOH A . 
O 6 HOH 224 924  129 HOH HOH A . 
O 6 HOH 225 925  105 HOH HOH A . 
O 6 HOH 226 926  59  HOH HOH A . 
O 6 HOH 227 927  159 HOH HOH A . 
O 6 HOH 228 928  189 HOH HOH A . 
O 6 HOH 229 929  164 HOH HOH A . 
O 6 HOH 230 930  3   HOH HOH A . 
O 6 HOH 231 931  287 HOH HOH A . 
O 6 HOH 232 932  15  HOH HOH A . 
O 6 HOH 233 933  91  HOH HOH A . 
O 6 HOH 234 934  258 HOH HOH A . 
O 6 HOH 235 935  66  HOH HOH A . 
O 6 HOH 236 936  30  HOH HOH A . 
O 6 HOH 237 937  243 HOH HOH A . 
O 6 HOH 238 938  114 HOH HOH A . 
O 6 HOH 239 939  79  HOH HOH A . 
O 6 HOH 240 940  40  HOH HOH A . 
O 6 HOH 241 941  224 HOH HOH A . 
O 6 HOH 242 942  55  HOH HOH A . 
O 6 HOH 243 943  180 HOH HOH A . 
O 6 HOH 244 944  5   HOH HOH A . 
O 6 HOH 245 945  71  HOH HOH A . 
O 6 HOH 246 946  107 HOH HOH A . 
O 6 HOH 247 947  80  HOH HOH A . 
O 6 HOH 248 948  127 HOH HOH A . 
O 6 HOH 249 949  138 HOH HOH A . 
O 6 HOH 250 950  288 HOH HOH A . 
O 6 HOH 251 951  111 HOH HOH A . 
O 6 HOH 252 952  250 HOH HOH A . 
O 6 HOH 253 953  329 HOH HOH A . 
O 6 HOH 254 954  361 HOH HOH A . 
O 6 HOH 255 955  335 HOH HOH A . 
O 6 HOH 256 956  225 HOH HOH A . 
O 6 HOH 257 957  300 HOH HOH A . 
O 6 HOH 258 958  334 HOH HOH A . 
O 6 HOH 259 959  87  HOH HOH A . 
O 6 HOH 260 960  226 HOH HOH A . 
O 6 HOH 261 961  242 HOH HOH A . 
O 6 HOH 262 962  277 HOH HOH A . 
O 6 HOH 263 963  203 HOH HOH A . 
O 6 HOH 264 964  184 HOH HOH A . 
O 6 HOH 265 965  195 HOH HOH A . 
O 6 HOH 266 966  357 HOH HOH A . 
O 6 HOH 267 967  294 HOH HOH A . 
O 6 HOH 268 968  350 HOH HOH A . 
O 6 HOH 269 969  291 HOH HOH A . 
O 6 HOH 270 970  262 HOH HOH A . 
O 6 HOH 271 971  290 HOH HOH A . 
O 6 HOH 272 972  206 HOH HOH A . 
O 6 HOH 273 973  163 HOH HOH A . 
O 6 HOH 274 974  56  HOH HOH A . 
O 6 HOH 275 975  146 HOH HOH A . 
O 6 HOH 276 976  274 HOH HOH A . 
O 6 HOH 277 977  169 HOH HOH A . 
O 6 HOH 278 978  238 HOH HOH A . 
O 6 HOH 279 979  187 HOH HOH A . 
O 6 HOH 280 980  82  HOH HOH A . 
O 6 HOH 281 981  229 HOH HOH A . 
O 6 HOH 282 982  132 HOH HOH A . 
O 6 HOH 283 983  136 HOH HOH A . 
O 6 HOH 284 984  84  HOH HOH A . 
O 6 HOH 285 985  49  HOH HOH A . 
O 6 HOH 286 986  227 HOH HOH A . 
O 6 HOH 287 987  336 HOH HOH A . 
O 6 HOH 288 988  248 HOH HOH A . 
O 6 HOH 289 989  54  HOH HOH A . 
O 6 HOH 290 990  58  HOH HOH A . 
O 6 HOH 291 991  151 HOH HOH A . 
O 6 HOH 292 992  256 HOH HOH A . 
O 6 HOH 293 993  339 HOH HOH A . 
O 6 HOH 294 994  186 HOH HOH A . 
O 6 HOH 295 995  228 HOH HOH A . 
O 6 HOH 296 996  310 HOH HOH A . 
O 6 HOH 297 997  115 HOH HOH A . 
O 6 HOH 298 998  112 HOH HOH A . 
O 6 HOH 299 999  45  HOH HOH A . 
O 6 HOH 300 1000 276 HOH HOH A . 
O 6 HOH 301 1001 83  HOH HOH A . 
O 6 HOH 302 1002 199 HOH HOH A . 
O 6 HOH 303 1003 363 HOH HOH A . 
O 6 HOH 304 1004 328 HOH HOH A . 
O 6 HOH 305 1005 267 HOH HOH A . 
O 6 HOH 306 1006 331 HOH HOH A . 
O 6 HOH 307 1007 32  HOH HOH A . 
O 6 HOH 308 1008 354 HOH HOH A . 
O 6 HOH 309 1009 333 HOH HOH A . 
O 6 HOH 310 1010 337 HOH HOH A . 
O 6 HOH 311 1011 347 HOH HOH A . 
O 6 HOH 312 1012 221 HOH HOH A . 
O 6 HOH 313 1013 125 HOH HOH A . 
O 6 HOH 314 1014 204 HOH HOH A . 
O 6 HOH 315 1015 253 HOH HOH A . 
O 6 HOH 316 1016 183 HOH HOH A . 
O 6 HOH 317 1017 345 HOH HOH A . 
O 6 HOH 318 1018 364 HOH HOH A . 
O 6 HOH 319 1019 307 HOH HOH A . 
O 6 HOH 320 1020 358 HOH HOH A . 
O 6 HOH 321 1021 312 HOH HOH A . 
O 6 HOH 322 1022 193 HOH HOH A . 
O 6 HOH 323 1023 322 HOH HOH A . 
O 6 HOH 324 1024 311 HOH HOH A . 
O 6 HOH 325 1025 289 HOH HOH A . 
O 6 HOH 326 1026 265 HOH HOH A . 
O 6 HOH 327 1027 160 HOH HOH A . 
O 6 HOH 328 1028 218 HOH HOH A . 
O 6 HOH 329 1029 246 HOH HOH A . 
O 6 HOH 330 1030 234 HOH HOH A . 
O 6 HOH 331 1031 275 HOH HOH A . 
O 6 HOH 332 1032 279 HOH HOH A . 
O 6 HOH 333 1033 309 HOH HOH A . 
O 6 HOH 334 1034 156 HOH HOH A . 
O 6 HOH 335 1035 355 HOH HOH A . 
O 6 HOH 336 1036 306 HOH HOH A . 
O 6 HOH 337 1037 304 HOH HOH A . 
O 6 HOH 338 1038 259 HOH HOH A . 
O 6 HOH 339 1039 303 HOH HOH A . 
O 6 HOH 340 1040 216 HOH HOH A . 
O 6 HOH 341 1041 106 HOH HOH A . 
O 6 HOH 342 1042 173 HOH HOH A . 
O 6 HOH 343 1043 340 HOH HOH A . 
O 6 HOH 344 1044 245 HOH HOH A . 
O 6 HOH 345 1045 165 HOH HOH A . 
O 6 HOH 346 1046 269 HOH HOH A . 
O 6 HOH 347 1047 214 HOH HOH A . 
O 6 HOH 348 1048 324 HOH HOH A . 
O 6 HOH 349 1049 261 HOH HOH A . 
O 6 HOH 350 1050 280 HOH HOH A . 
O 6 HOH 351 1051 356 HOH HOH A . 
O 6 HOH 352 1052 313 HOH HOH A . 
O 6 HOH 353 1053 342 HOH HOH A . 
O 6 HOH 354 1054 197 HOH HOH A . 
O 6 HOH 355 1055 305 HOH HOH A . 
O 6 HOH 356 1056 353 HOH HOH A . 
O 6 HOH 357 1057 297 HOH HOH A . 
O 6 HOH 358 1058 282 HOH HOH A . 
O 6 HOH 359 1059 196 HOH HOH A . 
O 6 HOH 360 1060 327 HOH HOH A . 
O 6 HOH 361 1061 149 HOH HOH A . 
O 6 HOH 362 1062 360 HOH HOH A . 
O 6 HOH 363 1063 207 HOH HOH A . 
O 6 HOH 364 1064 174 HOH HOH A . 
O 6 HOH 365 1065 308 HOH HOH A . 
O 6 HOH 366 1066 302 HOH HOH A . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC ? ? ? 5.8.0419 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? SCALA  ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? MOLREP ? ? ? .        4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9AVH 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     56.035 
_cell.length_a_esd                 ? 
_cell.length_b                     82.746 
_cell.length_b_esd                 ? 
_cell.length_c                     116.837 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9AVH 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9AVH 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.16 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          42.96 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              8.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '12% v/v glycerol, 1.5 M ammonium sulfate, 0.1 mM Tris/HCl, pH 8.5' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            291 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2021-03-07 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.979257 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'ALBA BEAMLINE XALOC' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.979257 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   XALOC 
_diffrn_source.pdbx_synchrotron_site       ALBA 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9AVH 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.8 
_reflns.d_resolution_low                               116.84 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     50514 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           98.9 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                6.7 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          12.2 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   ? 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.097 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.8 
_reflns_shell.d_res_low                                     1.9 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           2.7 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             7207 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               6.8 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  ? 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          98.2 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.843 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            -0.296 
_refine.aniso_B[1][2]                            -0.000 
_refine.aniso_B[1][3]                            0.000 
_refine.aniso_B[2][2]                            -1.286 
_refine.aniso_B[2][3]                            -0.000 
_refine.aniso_B[3][3]                            1.582 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               22.479 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.974 
_refine.correlation_coeff_Fo_to_Fc_free          0.959 
_refine.details                                  'Hydrogens have been added in their riding positions' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9AVH 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.800 
_refine.ls_d_res_low                             67.526 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     50458 
_refine.ls_number_reflns_R_free                  2464 
_refine.ls_number_reflns_R_work                  47994 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    98.699 
_refine.ls_percent_reflns_R_free                 4.883 
_refine.ls_R_factor_all                          0.146 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.1883 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1434 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.110 
_refine.pdbx_overall_ESU_R_Free                  0.111 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             2.532 
_refine.overall_SU_ML                            0.077 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.pdbx_number_atoms_protein        4407 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         124 
_refine_hist.number_atoms_solvent             366 
_refine_hist.number_atoms_total               4897 
_refine_hist.d_res_high                       1.800 
_refine_hist.d_res_low                        67.526 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.008  0.012  4640 ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.016  4276 ? r_bond_other_d                 ? ? 
'X-RAY DIFFRACTION' ? 1.665  1.803  6345 ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 0.569  1.739  9850 ? r_angle_other_deg              ? ? 
'X-RAY DIFFRACTION' ? 6.641  5.000  579  ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 6.812  5.000  27   ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.037  20.000 1    ? r_dihedral_angle_other_2_deg   ? ? 
'X-RAY DIFFRACTION' ? 11.679 10.000 693  ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 15.553 10.000 195  ? r_dihedral_angle_6_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.083  0.200  722  ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.006  0.200  1    ? r_chiral_restr_other           ? ? 
'X-RAY DIFFRACTION' ? 0.010  0.020  5483 ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.020  1026 ? r_gen_planes_other             ? ? 
'X-RAY DIFFRACTION' ? 0.218  0.200  935  ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.198  0.200  4168 ? r_symmetry_nbd_other           ? ? 
'X-RAY DIFFRACTION' ? 0.178  0.200  2351 ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.082  0.200  2354 ? r_symmetry_nbtor_other         ? ? 
'X-RAY DIFFRACTION' ? 0.144  0.200  294  ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.196  0.200  15   ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.253  0.200  61   ? r_nbd_other                    ? ? 
'X-RAY DIFFRACTION' ? 0.186  0.200  8    ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 1.781  2.186  2316 ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 1.780  2.186  2316 ? r_mcbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 2.463  3.920  2895 ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 2.464  3.920  2896 ? r_mcangle_other                ? ? 
'X-RAY DIFFRACTION' ? 3.039  2.562  2324 ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 2.995  2.519  2301 ? r_scbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 4.562  4.540  3450 ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 4.486  4.462  3415 ? r_scangle_other                ? ? 
'X-RAY DIFFRACTION' ? 7.418  23.324 5246 ? r_lrange_it                    ? ? 
'X-RAY DIFFRACTION' ? 7.321  22.924 5167 ? r_lrange_other                 ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.800 1.847  3699 . 172 3451 97.9454 . 0.221 . . 0.220 . . . . . 0.196 . 20 . 0.961 0.957 0.240 
'X-RAY DIFFRACTION' 1.847 1.897  3648 . 177 3397 97.9715 . 0.204 . . 0.201 . . . . . 0.177 . 20 . 0.969 0.951 0.260 
'X-RAY DIFFRACTION' 1.897 1.952  3525 . 183 3270 97.9574 . 0.189 . . 0.188 . . . . . 0.161 . 20 . 0.974 0.970 0.209 
'X-RAY DIFFRACTION' 1.952 2.012  3458 . 171 3221 98.0914 . 0.164 . . 0.162 . . . . . 0.139 . 20 . 0.982 0.972 0.211 
'X-RAY DIFFRACTION' 2.012 2.078  3354 . 174 3126 98.3900 . 0.157 . . 0.155 . . . . . 0.133 . 20 . 0.983 0.979 0.190 
'X-RAY DIFFRACTION' 2.078 2.151  3179 . 154 2985 98.7417 . 0.146 . . 0.143 . . . . . 0.124 . 20 . 0.986 0.977 0.191 
'X-RAY DIFFRACTION' 2.151 2.232  3152 . 162 2932 98.1599 . 0.140 . . 0.137 . . . . . 0.120 . 20 . 0.988 0.977 0.186 
'X-RAY DIFFRACTION' 2.232 2.323  3004 . 150 2817 98.7683 . 0.133 . . 0.131 . . . . . 0.115 . 20 . 0.989 0.981 0.167 
'X-RAY DIFFRACTION' 2.323 2.426  2890 . 128 2727 98.7889 . 0.135 . . 0.132 . . . . . 0.115 . 20 . 0.989 0.977 0.198 
'X-RAY DIFFRACTION' 2.426 2.545  2762 . 148 2589 99.0949 . 0.133 . . 0.131 . . . . . 0.115 . 20 . 0.990 0.981 0.174 
'X-RAY DIFFRACTION' 2.545 2.682  2629 . 129 2472 98.9350 . 0.133 . . 0.130 . . . . . 0.115 . 20 . 0.990 0.980 0.189 
'X-RAY DIFFRACTION' 2.682 2.845  2511 . 126 2369 99.3628 . 0.140 . . 0.137 . . . . . 0.123 . 20 . 0.988 0.979 0.190 
'X-RAY DIFFRACTION' 2.845 3.041  2346 . 92  2239 99.3606 . 0.137 . . 0.135 . . . . . 0.123 . 20 . 0.988 0.978 0.190 
'X-RAY DIFFRACTION' 3.041 3.284  2223 . 93  2116 99.3702 . 0.135 . . 0.133 . . . . . 0.126 . 20 . 0.989 0.983 0.166 
'X-RAY DIFFRACTION' 3.284 3.596  2035 . 91  1930 99.3120 . 0.138 . . 0.136 . . . . . 0.130 . 20 . 0.989 0.981 0.181 
'X-RAY DIFFRACTION' 3.596 4.019  1850 . 77  1765 99.5676 . 0.132 . . 0.130 . . . . . 0.129 . 20 . 0.990 0.985 0.163 
'X-RAY DIFFRACTION' 4.019 4.638  1654 . 93  1554 99.5768 . 0.122 . . 0.119 . . . . . 0.121 . 20 . 0.992 0.982 0.183 
'X-RAY DIFFRACTION' 4.638 5.674  1413 . 59  1347 99.5046 . 0.142 . . 0.140 . . . . . 0.141 . 20 . 0.990 0.981 0.180 
'X-RAY DIFFRACTION' 5.674 7.996  1120 . 52  1059 99.1964 . 0.181 . . 0.180 . . . . . 0.177 . 20 . 0.985 0.977 0.208 
'X-RAY DIFFRACTION' 7.996 67.526 672  . 33  629  98.5119 . 0.172 . . 0.170 . . . . . 0.172 . 20 . 0.981 0.980 0.198 
# 
_struct.entry_id                     9AVH 
_struct.title                        'Crystal structure of an aryl-alcohol-oxidase from Bjerkandera adusta.' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9AVH 
_struct_keywords.text            'AAO, BJERKANDERA ADUSTA, OXIDOREDUCTASE, FLAVOPROTEIN' 
_struct_keywords.pdbx_keywords   OXIDOREDUCTASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 4 ? 
F N N 4 ? 
G N N 4 ? 
H N N 4 ? 
I N N 5 ? 
J N N 5 ? 
K N N 5 ? 
L N N 5 ? 
M N N 5 ? 
N N N 5 ? 
O N N 6 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    PDB 
_struct_ref.db_code                    9AVH 
_struct_ref.pdbx_db_accession          9AVH 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   ? 
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9AVH 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 580 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             9AVH 
_struct_ref_seq.db_align_beg                  0 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  579 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       0 
_struct_ref_seq.pdbx_auth_seq_align_end       579 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 3880  ? 
1 MORE         -64   ? 
1 'SSA (A^2)'  20120 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASP A 7   ? LEU A 11  ? ASP A 6   LEU A 10  5 ? 5  
HELX_P HELX_P2  AA2 ALA A 26  ? THR A 35  ? ALA A 25  THR A 34  1 ? 10 
HELX_P HELX_P3  AA3 ILE A 54  ? VAL A 59  ? ILE A 53  VAL A 58  1 ? 6  
HELX_P HELX_P4  AA4 PRO A 60  ? LEU A 67  ? PRO A 59  LEU A 66  5 ? 8  
HELX_P HELX_P5  AA5 GLN A 81  ? ASP A 85  ? GLN A 80  ASP A 84  5 ? 5  
HELX_P HELX_P6  AA6 GLY A 98  ? VAL A 103 ? GLY A 97  VAL A 102 5 ? 6  
HELX_P HELX_P7  AA7 SER A 112 ? GLY A 124 ? SER A 111 GLY A 123 1 ? 13 
HELX_P HELX_P8  AA8 ASP A 125 ? TRP A 128 ? ASP A 124 TRP A 127 5 ? 4  
HELX_P HELX_P9  AA9 SER A 129 ? ASN A 140 ? SER A 128 ASN A 139 1 ? 12 
HELX_P HELX_P10 AB1 ASP A 157 ? HIS A 161 ? ASP A 156 HIS A 160 5 ? 5  
HELX_P HELX_P11 AB2 LEU A 177 ? ALA A 187 ? LEU A 176 ALA A 186 1 ? 11 
HELX_P HELX_P12 AB3 HIS A 220 ? PHE A 225 ? HIS A 219 PHE A 224 1 ? 6  
HELX_P HELX_P13 AB4 PHE A 225 ? MET A 230 ? PHE A 224 MET A 229 1 ? 6  
HELX_P HELX_P14 AB5 ALA A 284 ? SER A 296 ? ALA A 283 SER A 295 1 ? 13 
HELX_P HELX_P15 AB6 ASP A 300 ? GLY A 308 ? ASP A 299 GLY A 307 1 ? 9  
HELX_P HELX_P16 AB7 TYR A 340 ? ASP A 346 ? TYR A 339 ASP A 345 1 ? 7  
HELX_P HELX_P17 AB8 ASP A 346 ? ARG A 361 ? ASP A 345 ARG A 360 1 ? 16 
HELX_P HELX_P18 AB9 GLY A 363 ? ALA A 367 ? GLY A 362 ALA A 366 5 ? 5  
HELX_P HELX_P19 AC1 ASP A 382 ? ARG A 387 ? ASP A 381 ARG A 386 5 ? 6  
HELX_P HELX_P20 AC2 SER A 457 ? VAL A 475 ? SER A 456 VAL A 474 1 ? 19 
HELX_P HELX_P21 AC3 SER A 477 ? ASP A 482 ? SER A 476 ASP A 481 1 ? 6  
HELX_P HELX_P22 AC4 GLY A 489 ? ASP A 493 ? GLY A 488 ASP A 492 1 ? 5  
HELX_P HELX_P23 AC5 ASP A 497 ? THR A 509 ? ASP A 496 THR A 508 1 ? 13 
HELX_P HELX_P24 AC6 ASP A 547 ? LEU A 551 ? ASP A 546 LEU A 550 5 ? 5  
HELX_P HELX_P25 AC7 PRO A 559 ? LYS A 579 ? PRO A 558 LYS A 578 1 ? 21 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          LEU 
_struct_mon_prot_cis.label_seq_id           67 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           LEU 
_struct_mon_prot_cis.auth_seq_id            66 
_struct_mon_prot_cis.auth_asym_id           A 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    68 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     67 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    A 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       1.70 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 5 ? 
AA3 ? 2 ? 
AA4 ? 2 ? 
AA5 ? 6 ? 
AA6 ? 6 ? 
AA7 ? 2 ? 
AA8 ? 2 ? 
AA9 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? anti-parallel 
AA1 5 6 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? parallel      
AA2 3 4 ? parallel      
AA2 4 5 ? parallel      
AA3 1 2 ? anti-parallel 
AA4 1 2 ? parallel      
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA5 5 6 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA6 4 5 ? anti-parallel 
AA6 5 6 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA8 1 2 ? parallel      
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LEU A 235 ? LEU A 238 ? LEU A 234 LEU A 237 
AA1 2 VAL A 42  ? ILE A 45  ? VAL A 41  ILE A 44  
AA1 3 VAL A 15  ? VAL A 21  ? VAL A 14  VAL A 20  
AA1 4 SER A 272 ? LEU A 282 ? SER A 271 LEU A 281 
AA1 5 LEU A 255 ? ALA A 264 ? LEU A 254 ALA A 263 
AA1 6 THR A 242 ? THR A 252 ? THR A 241 THR A 251 
AA2 1 LEU A 235 ? LEU A 238 ? LEU A 234 LEU A 237 
AA2 2 VAL A 42  ? ILE A 45  ? VAL A 41  ILE A 44  
AA2 3 VAL A 15  ? VAL A 21  ? VAL A 14  VAL A 20  
AA2 4 SER A 272 ? LEU A 282 ? SER A 271 LEU A 281 
AA2 5 LEU A 543 ? VAL A 545 ? LEU A 542 VAL A 544 
AA3 1 MET A 73  ? THR A 77  ? MET A 72  THR A 76  
AA3 2 PRO A 90  ? GLY A 94  ? PRO A 89  GLY A 93  
AA4 1 SER A 141 ? LEU A 143 ? SER A 140 LEU A 142 
AA4 2 VAL A 166 ? LEU A 168 ? VAL A 165 LEU A 167 
AA5 1 GLY A 205 ? ILE A 208 ? GLY A 204 ILE A 207 
AA5 2 GLY A 372 ? PHE A 376 ? GLY A 371 PHE A 375 
AA5 3 ILE A 400 ? SER A 405 ? ILE A 399 SER A 404 
AA5 4 PHE A 421 ? VAL A 428 ? PHE A 420 VAL A 427 
AA5 5 PRO A 326 ? VAL A 334 ? PRO A 325 VAL A 333 
AA5 6 VAL A 484 ? THR A 488 ? VAL A 483 THR A 487 
AA6 1 GLY A 205 ? ILE A 208 ? GLY A 204 ILE A 207 
AA6 2 GLY A 372 ? PHE A 376 ? GLY A 371 PHE A 375 
AA6 3 ILE A 400 ? SER A 405 ? ILE A 399 SER A 404 
AA6 4 PHE A 421 ? VAL A 428 ? PHE A 420 VAL A 427 
AA6 5 PRO A 326 ? VAL A 334 ? PRO A 325 VAL A 333 
AA6 6 VAL A 510 ? THR A 511 ? VAL A 509 THR A 510 
AA7 1 ILE A 213 ? LEU A 214 ? ILE A 212 LEU A 213 
AA7 2 GLU A 217 ? ARG A 218 ? GLU A 216 ARG A 217 
AA8 1 ILE A 298 ? GLY A 299 ? ILE A 297 GLY A 298 
AA8 2 VAL A 313 ? ASP A 314 ? VAL A 312 ASP A 313 
AA9 1 LYS A 320 ? LEU A 322 ? LYS A 319 LEU A 321 
AA9 2 GLY A 435 ? ARG A 438 ? GLY A 434 ARG A 437 
AA9 3 LEU A 449 ? ASP A 451 ? LEU A 448 ASP A 450 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O LEU A 238 ? O LEU A 237 N LEU A 44  ? N LEU A 43  
AA1 2 3 O LEU A 43  ? O LEU A 42  N VAL A 20  ? N VAL A 19  
AA1 3 4 N ILE A 19  ? N ILE A 18  O VAL A 281 ? O VAL A 280 
AA1 4 5 O SER A 272 ? O SER A 271 N PHE A 263 ? N PHE A 262 
AA1 5 6 O SER A 257 ? O SER A 256 N THR A 249 ? N THR A 248 
AA2 1 2 O LEU A 238 ? O LEU A 237 N LEU A 44  ? N LEU A 43  
AA2 2 3 O LEU A 43  ? O LEU A 42  N VAL A 20  ? N VAL A 19  
AA2 3 4 N ILE A 19  ? N ILE A 18  O VAL A 281 ? O VAL A 280 
AA2 4 5 N LEU A 282 ? N LEU A 281 O ARG A 544 ? O ARG A 543 
AA3 1 2 N TRP A 74  ? N TRP A 73  O LYS A 93  ? O LYS A 92  
AA4 1 2 N ARG A 142 ? N ARG A 141 O LEU A 168 ? O LEU A 167 
AA5 1 2 N GLY A 207 ? N GLY A 206 O LEU A 373 ? O LEU A 372 
AA5 2 3 N GLY A 374 ? N GLY A 373 O LEU A 402 ? O LEU A 401 
AA5 3 4 N ILE A 403 ? N ILE A 402 O HIS A 425 ? O HIS A 424 
AA5 4 5 O ALA A 426 ? O ALA A 425 N MET A 328 ? N MET A 327 
AA5 5 6 N GLN A 333 ? N GLN A 332 O GLU A 485 ? O GLU A 484 
AA6 1 2 N GLY A 207 ? N GLY A 206 O LEU A 373 ? O LEU A 372 
AA6 2 3 N GLY A 374 ? N GLY A 373 O LEU A 402 ? O LEU A 401 
AA6 3 4 N ILE A 403 ? N ILE A 402 O HIS A 425 ? O HIS A 424 
AA6 4 5 O ALA A 426 ? O ALA A 425 N MET A 328 ? N MET A 327 
AA6 5 6 N ILE A 327 ? N ILE A 326 O VAL A 510 ? O VAL A 509 
AA7 1 2 N LEU A 214 ? N LEU A 213 O GLU A 217 ? O GLU A 216 
AA8 1 2 N GLY A 299 ? N GLY A 298 O VAL A 313 ? O VAL A 312 
AA9 1 2 N LEU A 322 ? N LEU A 321 O GLY A 435 ? O GLY A 434 
AA9 2 3 N ARG A 438 ? N ARG A 437 O LEU A 449 ? O LEU A 448 
# 
_pdbx_entry_details.entry_id                   9AVH 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 NE A ARG 270 ? ? CZ A ARG 270 ? ? NH1 A ARG 270 ? ? 124.37 120.30 4.07  0.50 N 
2 1 NE A ARG 270 ? ? CZ A ARG 270 ? ? NH2 A ARG 270 ? ? 114.93 120.30 -5.37 0.50 N 
3 1 CB A LEU 454 ? ? CG A LEU 454 ? ? CD2 A LEU 454 ? ? 121.24 111.00 10.24 1.70 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 LYS A 38  ? ? -132.82 -44.45  
2  1 SER A 110 ? ? 82.98   172.16  
3  1 THR A 248 ? ? -123.07 -163.04 
4  1 ASN A 359 ? ? -147.67 21.09   
5  1 ASN A 380 ? ? -76.93  21.97   
6  1 ASN A 405 ? ? -87.73  40.55   
7  1 GLU A 410 ? ? -138.05 -98.84  
8  1 TRP A 512 ? ? 72.51   50.90   
9  1 HIS A 513 ? ? -119.69 52.45   
10 1 CYS A 516 ? ? 84.28   19.56   
11 1 ALA A 518 ? ? -145.50 59.69   
12 1 LEU A 534 ? ? 81.24   2.14    
13 1 ASP A 546 ? ? 176.47  -172.70 
14 1 ALA A 555 ? ? -84.82  42.64   
15 1 THR A 556 ? ? 179.59  177.32  
# 
_pdbx_validate_planes.id              1 
_pdbx_validate_planes.PDB_model_num   1 
_pdbx_validate_planes.auth_comp_id    ARG 
_pdbx_validate_planes.auth_asym_id    A 
_pdbx_validate_planes.auth_seq_id     109 
_pdbx_validate_planes.PDB_ins_code    ? 
_pdbx_validate_planes.label_alt_id    ? 
_pdbx_validate_planes.rmsd            0.098 
_pdbx_validate_planes.type            'SIDE CHAIN' 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 A MET 0 ? A MET 1 
2 1 Y 1 A VAL 1 ? A VAL 2 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N      N N N 1   
ALA CA     C N S 2   
ALA C      C N N 3   
ALA O      O N N 4   
ALA CB     C N N 5   
ALA OXT    O N N 6   
ALA H      H N N 7   
ALA H2     H N N 8   
ALA HA     H N N 9   
ALA HB1    H N N 10  
ALA HB2    H N N 11  
ALA HB3    H N N 12  
ALA HXT    H N N 13  
ANN C8     C N N 14  
ANN O3     O N N 15  
ANN C5     C Y N 16  
ANN C6     C Y N 17  
ANN C7     C Y N 18  
ANN C2     C Y N 19  
ANN C3     C Y N 20  
ANN C4     C Y N 21  
ANN C1     C N N 22  
ANN O1     O N N 23  
ANN O2     O N N 24  
ANN H81    H N N 25  
ANN H82    H N N 26  
ANN H83    H N N 27  
ANN H6     H N N 28  
ANN H7     H N N 29  
ANN H3     H N N 30  
ANN H4     H N N 31  
ANN HO1    H N N 32  
ARG N      N N N 33  
ARG CA     C N S 34  
ARG C      C N N 35  
ARG O      O N N 36  
ARG CB     C N N 37  
ARG CG     C N N 38  
ARG CD     C N N 39  
ARG NE     N N N 40  
ARG CZ     C N N 41  
ARG NH1    N N N 42  
ARG NH2    N N N 43  
ARG OXT    O N N 44  
ARG H      H N N 45  
ARG H2     H N N 46  
ARG HA     H N N 47  
ARG HB2    H N N 48  
ARG HB3    H N N 49  
ARG HG2    H N N 50  
ARG HG3    H N N 51  
ARG HD2    H N N 52  
ARG HD3    H N N 53  
ARG HE     H N N 54  
ARG HH11   H N N 55  
ARG HH12   H N N 56  
ARG HH21   H N N 57  
ARG HH22   H N N 58  
ARG HXT    H N N 59  
ASN N      N N N 60  
ASN CA     C N S 61  
ASN C      C N N 62  
ASN O      O N N 63  
ASN CB     C N N 64  
ASN CG     C N N 65  
ASN OD1    O N N 66  
ASN ND2    N N N 67  
ASN OXT    O N N 68  
ASN H      H N N 69  
ASN H2     H N N 70  
ASN HA     H N N 71  
ASN HB2    H N N 72  
ASN HB3    H N N 73  
ASN HD21   H N N 74  
ASN HD22   H N N 75  
ASN HXT    H N N 76  
ASP N      N N N 77  
ASP CA     C N S 78  
ASP C      C N N 79  
ASP O      O N N 80  
ASP CB     C N N 81  
ASP CG     C N N 82  
ASP OD1    O N N 83  
ASP OD2    O N N 84  
ASP OXT    O N N 85  
ASP H      H N N 86  
ASP H2     H N N 87  
ASP HA     H N N 88  
ASP HB2    H N N 89  
ASP HB3    H N N 90  
ASP HD2    H N N 91  
ASP HXT    H N N 92  
CYS N      N N N 93  
CYS CA     C N R 94  
CYS C      C N N 95  
CYS O      O N N 96  
CYS CB     C N N 97  
CYS SG     S N N 98  
CYS OXT    O N N 99  
CYS H      H N N 100 
CYS H2     H N N 101 
CYS HA     H N N 102 
CYS HB2    H N N 103 
CYS HB3    H N N 104 
CYS HG     H N N 105 
CYS HXT    H N N 106 
FAD PA     P N R 107 
FAD O1A    O N N 108 
FAD O2A    O N N 109 
FAD O5B    O N N 110 
FAD C5B    C N N 111 
FAD C4B    C N R 112 
FAD O4B    O N N 113 
FAD C3B    C N S 114 
FAD O3B    O N N 115 
FAD C2B    C N R 116 
FAD O2B    O N N 117 
FAD C1B    C N R 118 
FAD N9A    N Y N 119 
FAD C8A    C Y N 120 
FAD N7A    N Y N 121 
FAD C5A    C Y N 122 
FAD C6A    C Y N 123 
FAD N6A    N N N 124 
FAD N1A    N Y N 125 
FAD C2A    C Y N 126 
FAD N3A    N Y N 127 
FAD C4A    C Y N 128 
FAD N1     N N N 129 
FAD C2     C N N 130 
FAD O2     O N N 131 
FAD N3     N N N 132 
FAD C4     C N N 133 
FAD O4     O N N 134 
FAD C4X    C N N 135 
FAD N5     N N N 136 
FAD C5X    C Y N 137 
FAD C6     C Y N 138 
FAD C7     C Y N 139 
FAD C7M    C N N 140 
FAD C8     C Y N 141 
FAD C8M    C N N 142 
FAD C9     C Y N 143 
FAD C9A    C Y N 144 
FAD N10    N N N 145 
FAD C10    C N N 146 
FAD "C1'"  C N N 147 
FAD "C2'"  C N S 148 
FAD "O2'"  O N N 149 
FAD "C3'"  C N S 150 
FAD "O3'"  O N N 151 
FAD "C4'"  C N R 152 
FAD "O4'"  O N N 153 
FAD "C5'"  C N N 154 
FAD "O5'"  O N N 155 
FAD P      P N R 156 
FAD O1P    O N N 157 
FAD O2P    O N N 158 
FAD O3P    O N N 159 
FAD HOA2   H N N 160 
FAD H51A   H N N 161 
FAD H52A   H N N 162 
FAD H4B    H N N 163 
FAD H3B    H N N 164 
FAD HO3A   H N N 165 
FAD H2B    H N N 166 
FAD HO2A   H N N 167 
FAD H1B    H N N 168 
FAD H8A    H N N 169 
FAD H61A   H N N 170 
FAD H62A   H N N 171 
FAD H2A    H N N 172 
FAD HN3    H N N 173 
FAD H6     H N N 174 
FAD HM71   H N N 175 
FAD HM72   H N N 176 
FAD HM73   H N N 177 
FAD HM81   H N N 178 
FAD HM82   H N N 179 
FAD HM83   H N N 180 
FAD H9     H N N 181 
FAD "H1'1" H N N 182 
FAD "H1'2" H N N 183 
FAD "H2'"  H N N 184 
FAD "HO2'" H N N 185 
FAD "H3'"  H N N 186 
FAD "HO3'" H N N 187 
FAD "H4'"  H N N 188 
FAD "HO4'" H N N 189 
FAD "H5'1" H N N 190 
FAD "H5'2" H N N 191 
FAD HOP2   H N N 192 
GLN N      N N N 193 
GLN CA     C N S 194 
GLN C      C N N 195 
GLN O      O N N 196 
GLN CB     C N N 197 
GLN CG     C N N 198 
GLN CD     C N N 199 
GLN OE1    O N N 200 
GLN NE2    N N N 201 
GLN OXT    O N N 202 
GLN H      H N N 203 
GLN H2     H N N 204 
GLN HA     H N N 205 
GLN HB2    H N N 206 
GLN HB3    H N N 207 
GLN HG2    H N N 208 
GLN HG3    H N N 209 
GLN HE21   H N N 210 
GLN HE22   H N N 211 
GLN HXT    H N N 212 
GLU N      N N N 213 
GLU CA     C N S 214 
GLU C      C N N 215 
GLU O      O N N 216 
GLU CB     C N N 217 
GLU CG     C N N 218 
GLU CD     C N N 219 
GLU OE1    O N N 220 
GLU OE2    O N N 221 
GLU OXT    O N N 222 
GLU H      H N N 223 
GLU H2     H N N 224 
GLU HA     H N N 225 
GLU HB2    H N N 226 
GLU HB3    H N N 227 
GLU HG2    H N N 228 
GLU HG3    H N N 229 
GLU HE2    H N N 230 
GLU HXT    H N N 231 
GLY N      N N N 232 
GLY CA     C N N 233 
GLY C      C N N 234 
GLY O      O N N 235 
GLY OXT    O N N 236 
GLY H      H N N 237 
GLY H2     H N N 238 
GLY HA2    H N N 239 
GLY HA3    H N N 240 
GLY HXT    H N N 241 
GOL C1     C N N 242 
GOL O1     O N N 243 
GOL C2     C N N 244 
GOL O2     O N N 245 
GOL C3     C N N 246 
GOL O3     O N N 247 
GOL H11    H N N 248 
GOL H12    H N N 249 
GOL HO1    H N N 250 
GOL H2     H N N 251 
GOL HO2    H N N 252 
GOL H31    H N N 253 
GOL H32    H N N 254 
GOL HO3    H N N 255 
HIS N      N N N 256 
HIS CA     C N S 257 
HIS C      C N N 258 
HIS O      O N N 259 
HIS CB     C N N 260 
HIS CG     C Y N 261 
HIS ND1    N Y N 262 
HIS CD2    C Y N 263 
HIS CE1    C Y N 264 
HIS NE2    N Y N 265 
HIS OXT    O N N 266 
HIS H      H N N 267 
HIS H2     H N N 268 
HIS HA     H N N 269 
HIS HB2    H N N 270 
HIS HB3    H N N 271 
HIS HD1    H N N 272 
HIS HD2    H N N 273 
HIS HE1    H N N 274 
HIS HE2    H N N 275 
HIS HXT    H N N 276 
HOH O      O N N 277 
HOH H1     H N N 278 
HOH H2     H N N 279 
ILE N      N N N 280 
ILE CA     C N S 281 
ILE C      C N N 282 
ILE O      O N N 283 
ILE CB     C N S 284 
ILE CG1    C N N 285 
ILE CG2    C N N 286 
ILE CD1    C N N 287 
ILE OXT    O N N 288 
ILE H      H N N 289 
ILE H2     H N N 290 
ILE HA     H N N 291 
ILE HB     H N N 292 
ILE HG12   H N N 293 
ILE HG13   H N N 294 
ILE HG21   H N N 295 
ILE HG22   H N N 296 
ILE HG23   H N N 297 
ILE HD11   H N N 298 
ILE HD12   H N N 299 
ILE HD13   H N N 300 
ILE HXT    H N N 301 
LEU N      N N N 302 
LEU CA     C N S 303 
LEU C      C N N 304 
LEU O      O N N 305 
LEU CB     C N N 306 
LEU CG     C N N 307 
LEU CD1    C N N 308 
LEU CD2    C N N 309 
LEU OXT    O N N 310 
LEU H      H N N 311 
LEU H2     H N N 312 
LEU HA     H N N 313 
LEU HB2    H N N 314 
LEU HB3    H N N 315 
LEU HG     H N N 316 
LEU HD11   H N N 317 
LEU HD12   H N N 318 
LEU HD13   H N N 319 
LEU HD21   H N N 320 
LEU HD22   H N N 321 
LEU HD23   H N N 322 
LEU HXT    H N N 323 
LYS N      N N N 324 
LYS CA     C N S 325 
LYS C      C N N 326 
LYS O      O N N 327 
LYS CB     C N N 328 
LYS CG     C N N 329 
LYS CD     C N N 330 
LYS CE     C N N 331 
LYS NZ     N N N 332 
LYS OXT    O N N 333 
LYS H      H N N 334 
LYS H2     H N N 335 
LYS HA     H N N 336 
LYS HB2    H N N 337 
LYS HB3    H N N 338 
LYS HG2    H N N 339 
LYS HG3    H N N 340 
LYS HD2    H N N 341 
LYS HD3    H N N 342 
LYS HE2    H N N 343 
LYS HE3    H N N 344 
LYS HZ1    H N N 345 
LYS HZ2    H N N 346 
LYS HZ3    H N N 347 
LYS HXT    H N N 348 
MET N      N N N 349 
MET CA     C N S 350 
MET C      C N N 351 
MET O      O N N 352 
MET CB     C N N 353 
MET CG     C N N 354 
MET SD     S N N 355 
MET CE     C N N 356 
MET OXT    O N N 357 
MET H      H N N 358 
MET H2     H N N 359 
MET HA     H N N 360 
MET HB2    H N N 361 
MET HB3    H N N 362 
MET HG2    H N N 363 
MET HG3    H N N 364 
MET HE1    H N N 365 
MET HE2    H N N 366 
MET HE3    H N N 367 
MET HXT    H N N 368 
PHE N      N N N 369 
PHE CA     C N S 370 
PHE C      C N N 371 
PHE O      O N N 372 
PHE CB     C N N 373 
PHE CG     C Y N 374 
PHE CD1    C Y N 375 
PHE CD2    C Y N 376 
PHE CE1    C Y N 377 
PHE CE2    C Y N 378 
PHE CZ     C Y N 379 
PHE OXT    O N N 380 
PHE H      H N N 381 
PHE H2     H N N 382 
PHE HA     H N N 383 
PHE HB2    H N N 384 
PHE HB3    H N N 385 
PHE HD1    H N N 386 
PHE HD2    H N N 387 
PHE HE1    H N N 388 
PHE HE2    H N N 389 
PHE HZ     H N N 390 
PHE HXT    H N N 391 
PRO N      N N N 392 
PRO CA     C N S 393 
PRO C      C N N 394 
PRO O      O N N 395 
PRO CB     C N N 396 
PRO CG     C N N 397 
PRO CD     C N N 398 
PRO OXT    O N N 399 
PRO H      H N N 400 
PRO HA     H N N 401 
PRO HB2    H N N 402 
PRO HB3    H N N 403 
PRO HG2    H N N 404 
PRO HG3    H N N 405 
PRO HD2    H N N 406 
PRO HD3    H N N 407 
PRO HXT    H N N 408 
SER N      N N N 409 
SER CA     C N S 410 
SER C      C N N 411 
SER O      O N N 412 
SER CB     C N N 413 
SER OG     O N N 414 
SER OXT    O N N 415 
SER H      H N N 416 
SER H2     H N N 417 
SER HA     H N N 418 
SER HB2    H N N 419 
SER HB3    H N N 420 
SER HG     H N N 421 
SER HXT    H N N 422 
SO4 S      S N N 423 
SO4 O1     O N N 424 
SO4 O2     O N N 425 
SO4 O3     O N N 426 
SO4 O4     O N N 427 
THR N      N N N 428 
THR CA     C N S 429 
THR C      C N N 430 
THR O      O N N 431 
THR CB     C N R 432 
THR OG1    O N N 433 
THR CG2    C N N 434 
THR OXT    O N N 435 
THR H      H N N 436 
THR H2     H N N 437 
THR HA     H N N 438 
THR HB     H N N 439 
THR HG1    H N N 440 
THR HG21   H N N 441 
THR HG22   H N N 442 
THR HG23   H N N 443 
THR HXT    H N N 444 
TRP N      N N N 445 
TRP CA     C N S 446 
TRP C      C N N 447 
TRP O      O N N 448 
TRP CB     C N N 449 
TRP CG     C Y N 450 
TRP CD1    C Y N 451 
TRP CD2    C Y N 452 
TRP NE1    N Y N 453 
TRP CE2    C Y N 454 
TRP CE3    C Y N 455 
TRP CZ2    C Y N 456 
TRP CZ3    C Y N 457 
TRP CH2    C Y N 458 
TRP OXT    O N N 459 
TRP H      H N N 460 
TRP H2     H N N 461 
TRP HA     H N N 462 
TRP HB2    H N N 463 
TRP HB3    H N N 464 
TRP HD1    H N N 465 
TRP HE1    H N N 466 
TRP HE3    H N N 467 
TRP HZ2    H N N 468 
TRP HZ3    H N N 469 
TRP HH2    H N N 470 
TRP HXT    H N N 471 
TYR N      N N N 472 
TYR CA     C N S 473 
TYR C      C N N 474 
TYR O      O N N 475 
TYR CB     C N N 476 
TYR CG     C Y N 477 
TYR CD1    C Y N 478 
TYR CD2    C Y N 479 
TYR CE1    C Y N 480 
TYR CE2    C Y N 481 
TYR CZ     C Y N 482 
TYR OH     O N N 483 
TYR OXT    O N N 484 
TYR H      H N N 485 
TYR H2     H N N 486 
TYR HA     H N N 487 
TYR HB2    H N N 488 
TYR HB3    H N N 489 
TYR HD1    H N N 490 
TYR HD2    H N N 491 
TYR HE1    H N N 492 
TYR HE2    H N N 493 
TYR HH     H N N 494 
TYR HXT    H N N 495 
VAL N      N N N 496 
VAL CA     C N S 497 
VAL C      C N N 498 
VAL O      O N N 499 
VAL CB     C N N 500 
VAL CG1    C N N 501 
VAL CG2    C N N 502 
VAL OXT    O N N 503 
VAL H      H N N 504 
VAL H2     H N N 505 
VAL HA     H N N 506 
VAL HB     H N N 507 
VAL HG11   H N N 508 
VAL HG12   H N N 509 
VAL HG13   H N N 510 
VAL HG21   H N N 511 
VAL HG22   H N N 512 
VAL HG23   H N N 513 
VAL HXT    H N N 514 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N     CA     sing N N 1   
ALA N     H      sing N N 2   
ALA N     H2     sing N N 3   
ALA CA    C      sing N N 4   
ALA CA    CB     sing N N 5   
ALA CA    HA     sing N N 6   
ALA C     O      doub N N 7   
ALA C     OXT    sing N N 8   
ALA CB    HB1    sing N N 9   
ALA CB    HB2    sing N N 10  
ALA CB    HB3    sing N N 11  
ALA OXT   HXT    sing N N 12  
ANN C8    O3     sing N N 13  
ANN C8    H81    sing N N 14  
ANN C8    H82    sing N N 15  
ANN C8    H83    sing N N 16  
ANN O3    C5     sing N N 17  
ANN C5    C6     doub Y N 18  
ANN C5    C4     sing Y N 19  
ANN C6    C7     sing Y N 20  
ANN C6    H6     sing N N 21  
ANN C7    C2     doub Y N 22  
ANN C7    H7     sing N N 23  
ANN C2    C3     sing Y N 24  
ANN C2    C1     sing N N 25  
ANN C3    C4     doub Y N 26  
ANN C3    H3     sing N N 27  
ANN C4    H4     sing N N 28  
ANN C1    O1     sing N N 29  
ANN C1    O2     doub N N 30  
ANN O1    HO1    sing N N 31  
ARG N     CA     sing N N 32  
ARG N     H      sing N N 33  
ARG N     H2     sing N N 34  
ARG CA    C      sing N N 35  
ARG CA    CB     sing N N 36  
ARG CA    HA     sing N N 37  
ARG C     O      doub N N 38  
ARG C     OXT    sing N N 39  
ARG CB    CG     sing N N 40  
ARG CB    HB2    sing N N 41  
ARG CB    HB3    sing N N 42  
ARG CG    CD     sing N N 43  
ARG CG    HG2    sing N N 44  
ARG CG    HG3    sing N N 45  
ARG CD    NE     sing N N 46  
ARG CD    HD2    sing N N 47  
ARG CD    HD3    sing N N 48  
ARG NE    CZ     sing N N 49  
ARG NE    HE     sing N N 50  
ARG CZ    NH1    sing N N 51  
ARG CZ    NH2    doub N N 52  
ARG NH1   HH11   sing N N 53  
ARG NH1   HH12   sing N N 54  
ARG NH2   HH21   sing N N 55  
ARG NH2   HH22   sing N N 56  
ARG OXT   HXT    sing N N 57  
ASN N     CA     sing N N 58  
ASN N     H      sing N N 59  
ASN N     H2     sing N N 60  
ASN CA    C      sing N N 61  
ASN CA    CB     sing N N 62  
ASN CA    HA     sing N N 63  
ASN C     O      doub N N 64  
ASN C     OXT    sing N N 65  
ASN CB    CG     sing N N 66  
ASN CB    HB2    sing N N 67  
ASN CB    HB3    sing N N 68  
ASN CG    OD1    doub N N 69  
ASN CG    ND2    sing N N 70  
ASN ND2   HD21   sing N N 71  
ASN ND2   HD22   sing N N 72  
ASN OXT   HXT    sing N N 73  
ASP N     CA     sing N N 74  
ASP N     H      sing N N 75  
ASP N     H2     sing N N 76  
ASP CA    C      sing N N 77  
ASP CA    CB     sing N N 78  
ASP CA    HA     sing N N 79  
ASP C     O      doub N N 80  
ASP C     OXT    sing N N 81  
ASP CB    CG     sing N N 82  
ASP CB    HB2    sing N N 83  
ASP CB    HB3    sing N N 84  
ASP CG    OD1    doub N N 85  
ASP CG    OD2    sing N N 86  
ASP OD2   HD2    sing N N 87  
ASP OXT   HXT    sing N N 88  
CYS N     CA     sing N N 89  
CYS N     H      sing N N 90  
CYS N     H2     sing N N 91  
CYS CA    C      sing N N 92  
CYS CA    CB     sing N N 93  
CYS CA    HA     sing N N 94  
CYS C     O      doub N N 95  
CYS C     OXT    sing N N 96  
CYS CB    SG     sing N N 97  
CYS CB    HB2    sing N N 98  
CYS CB    HB3    sing N N 99  
CYS SG    HG     sing N N 100 
CYS OXT   HXT    sing N N 101 
FAD PA    O1A    doub N N 102 
FAD PA    O2A    sing N N 103 
FAD PA    O5B    sing N N 104 
FAD PA    O3P    sing N N 105 
FAD O2A   HOA2   sing N N 106 
FAD O5B   C5B    sing N N 107 
FAD C5B   C4B    sing N N 108 
FAD C5B   H51A   sing N N 109 
FAD C5B   H52A   sing N N 110 
FAD C4B   O4B    sing N N 111 
FAD C4B   C3B    sing N N 112 
FAD C4B   H4B    sing N N 113 
FAD O4B   C1B    sing N N 114 
FAD C3B   O3B    sing N N 115 
FAD C3B   C2B    sing N N 116 
FAD C3B   H3B    sing N N 117 
FAD O3B   HO3A   sing N N 118 
FAD C2B   O2B    sing N N 119 
FAD C2B   C1B    sing N N 120 
FAD C2B   H2B    sing N N 121 
FAD O2B   HO2A   sing N N 122 
FAD C1B   N9A    sing N N 123 
FAD C1B   H1B    sing N N 124 
FAD N9A   C8A    sing Y N 125 
FAD N9A   C4A    sing Y N 126 
FAD C8A   N7A    doub Y N 127 
FAD C8A   H8A    sing N N 128 
FAD N7A   C5A    sing Y N 129 
FAD C5A   C6A    sing Y N 130 
FAD C5A   C4A    doub Y N 131 
FAD C6A   N6A    sing N N 132 
FAD C6A   N1A    doub Y N 133 
FAD N6A   H61A   sing N N 134 
FAD N6A   H62A   sing N N 135 
FAD N1A   C2A    sing Y N 136 
FAD C2A   N3A    doub Y N 137 
FAD C2A   H2A    sing N N 138 
FAD N3A   C4A    sing Y N 139 
FAD N1    C2     sing N N 140 
FAD N1    C10    doub N N 141 
FAD C2    O2     doub N N 142 
FAD C2    N3     sing N N 143 
FAD N3    C4     sing N N 144 
FAD N3    HN3    sing N N 145 
FAD C4    O4     doub N N 146 
FAD C4    C4X    sing N N 147 
FAD C4X   N5     doub N N 148 
FAD C4X   C10    sing N N 149 
FAD N5    C5X    sing N N 150 
FAD C5X   C6     doub Y N 151 
FAD C5X   C9A    sing Y N 152 
FAD C6    C7     sing Y N 153 
FAD C6    H6     sing N N 154 
FAD C7    C7M    sing N N 155 
FAD C7    C8     doub Y N 156 
FAD C7M   HM71   sing N N 157 
FAD C7M   HM72   sing N N 158 
FAD C7M   HM73   sing N N 159 
FAD C8    C8M    sing N N 160 
FAD C8    C9     sing Y N 161 
FAD C8M   HM81   sing N N 162 
FAD C8M   HM82   sing N N 163 
FAD C8M   HM83   sing N N 164 
FAD C9    C9A    doub Y N 165 
FAD C9    H9     sing N N 166 
FAD C9A   N10    sing N N 167 
FAD N10   C10    sing N N 168 
FAD N10   "C1'"  sing N N 169 
FAD "C1'" "C2'"  sing N N 170 
FAD "C1'" "H1'1" sing N N 171 
FAD "C1'" "H1'2" sing N N 172 
FAD "C2'" "O2'"  sing N N 173 
FAD "C2'" "C3'"  sing N N 174 
FAD "C2'" "H2'"  sing N N 175 
FAD "O2'" "HO2'" sing N N 176 
FAD "C3'" "O3'"  sing N N 177 
FAD "C3'" "C4'"  sing N N 178 
FAD "C3'" "H3'"  sing N N 179 
FAD "O3'" "HO3'" sing N N 180 
FAD "C4'" "O4'"  sing N N 181 
FAD "C4'" "C5'"  sing N N 182 
FAD "C4'" "H4'"  sing N N 183 
FAD "O4'" "HO4'" sing N N 184 
FAD "C5'" "O5'"  sing N N 185 
FAD "C5'" "H5'1" sing N N 186 
FAD "C5'" "H5'2" sing N N 187 
FAD "O5'" P      sing N N 188 
FAD P     O1P    doub N N 189 
FAD P     O2P    sing N N 190 
FAD P     O3P    sing N N 191 
FAD O2P   HOP2   sing N N 192 
GLN N     CA     sing N N 193 
GLN N     H      sing N N 194 
GLN N     H2     sing N N 195 
GLN CA    C      sing N N 196 
GLN CA    CB     sing N N 197 
GLN CA    HA     sing N N 198 
GLN C     O      doub N N 199 
GLN C     OXT    sing N N 200 
GLN CB    CG     sing N N 201 
GLN CB    HB2    sing N N 202 
GLN CB    HB3    sing N N 203 
GLN CG    CD     sing N N 204 
GLN CG    HG2    sing N N 205 
GLN CG    HG3    sing N N 206 
GLN CD    OE1    doub N N 207 
GLN CD    NE2    sing N N 208 
GLN NE2   HE21   sing N N 209 
GLN NE2   HE22   sing N N 210 
GLN OXT   HXT    sing N N 211 
GLU N     CA     sing N N 212 
GLU N     H      sing N N 213 
GLU N     H2     sing N N 214 
GLU CA    C      sing N N 215 
GLU CA    CB     sing N N 216 
GLU CA    HA     sing N N 217 
GLU C     O      doub N N 218 
GLU C     OXT    sing N N 219 
GLU CB    CG     sing N N 220 
GLU CB    HB2    sing N N 221 
GLU CB    HB3    sing N N 222 
GLU CG    CD     sing N N 223 
GLU CG    HG2    sing N N 224 
GLU CG    HG3    sing N N 225 
GLU CD    OE1    doub N N 226 
GLU CD    OE2    sing N N 227 
GLU OE2   HE2    sing N N 228 
GLU OXT   HXT    sing N N 229 
GLY N     CA     sing N N 230 
GLY N     H      sing N N 231 
GLY N     H2     sing N N 232 
GLY CA    C      sing N N 233 
GLY CA    HA2    sing N N 234 
GLY CA    HA3    sing N N 235 
GLY C     O      doub N N 236 
GLY C     OXT    sing N N 237 
GLY OXT   HXT    sing N N 238 
GOL C1    O1     sing N N 239 
GOL C1    C2     sing N N 240 
GOL C1    H11    sing N N 241 
GOL C1    H12    sing N N 242 
GOL O1    HO1    sing N N 243 
GOL C2    O2     sing N N 244 
GOL C2    C3     sing N N 245 
GOL C2    H2     sing N N 246 
GOL O2    HO2    sing N N 247 
GOL C3    O3     sing N N 248 
GOL C3    H31    sing N N 249 
GOL C3    H32    sing N N 250 
GOL O3    HO3    sing N N 251 
HIS N     CA     sing N N 252 
HIS N     H      sing N N 253 
HIS N     H2     sing N N 254 
HIS CA    C      sing N N 255 
HIS CA    CB     sing N N 256 
HIS CA    HA     sing N N 257 
HIS C     O      doub N N 258 
HIS C     OXT    sing N N 259 
HIS CB    CG     sing N N 260 
HIS CB    HB2    sing N N 261 
HIS CB    HB3    sing N N 262 
HIS CG    ND1    sing Y N 263 
HIS CG    CD2    doub Y N 264 
HIS ND1   CE1    doub Y N 265 
HIS ND1   HD1    sing N N 266 
HIS CD2   NE2    sing Y N 267 
HIS CD2   HD2    sing N N 268 
HIS CE1   NE2    sing Y N 269 
HIS CE1   HE1    sing N N 270 
HIS NE2   HE2    sing N N 271 
HIS OXT   HXT    sing N N 272 
HOH O     H1     sing N N 273 
HOH O     H2     sing N N 274 
ILE N     CA     sing N N 275 
ILE N     H      sing N N 276 
ILE N     H2     sing N N 277 
ILE CA    C      sing N N 278 
ILE CA    CB     sing N N 279 
ILE CA    HA     sing N N 280 
ILE C     O      doub N N 281 
ILE C     OXT    sing N N 282 
ILE CB    CG1    sing N N 283 
ILE CB    CG2    sing N N 284 
ILE CB    HB     sing N N 285 
ILE CG1   CD1    sing N N 286 
ILE CG1   HG12   sing N N 287 
ILE CG1   HG13   sing N N 288 
ILE CG2   HG21   sing N N 289 
ILE CG2   HG22   sing N N 290 
ILE CG2   HG23   sing N N 291 
ILE CD1   HD11   sing N N 292 
ILE CD1   HD12   sing N N 293 
ILE CD1   HD13   sing N N 294 
ILE OXT   HXT    sing N N 295 
LEU N     CA     sing N N 296 
LEU N     H      sing N N 297 
LEU N     H2     sing N N 298 
LEU CA    C      sing N N 299 
LEU CA    CB     sing N N 300 
LEU CA    HA     sing N N 301 
LEU C     O      doub N N 302 
LEU C     OXT    sing N N 303 
LEU CB    CG     sing N N 304 
LEU CB    HB2    sing N N 305 
LEU CB    HB3    sing N N 306 
LEU CG    CD1    sing N N 307 
LEU CG    CD2    sing N N 308 
LEU CG    HG     sing N N 309 
LEU CD1   HD11   sing N N 310 
LEU CD1   HD12   sing N N 311 
LEU CD1   HD13   sing N N 312 
LEU CD2   HD21   sing N N 313 
LEU CD2   HD22   sing N N 314 
LEU CD2   HD23   sing N N 315 
LEU OXT   HXT    sing N N 316 
LYS N     CA     sing N N 317 
LYS N     H      sing N N 318 
LYS N     H2     sing N N 319 
LYS CA    C      sing N N 320 
LYS CA    CB     sing N N 321 
LYS CA    HA     sing N N 322 
LYS C     O      doub N N 323 
LYS C     OXT    sing N N 324 
LYS CB    CG     sing N N 325 
LYS CB    HB2    sing N N 326 
LYS CB    HB3    sing N N 327 
LYS CG    CD     sing N N 328 
LYS CG    HG2    sing N N 329 
LYS CG    HG3    sing N N 330 
LYS CD    CE     sing N N 331 
LYS CD    HD2    sing N N 332 
LYS CD    HD3    sing N N 333 
LYS CE    NZ     sing N N 334 
LYS CE    HE2    sing N N 335 
LYS CE    HE3    sing N N 336 
LYS NZ    HZ1    sing N N 337 
LYS NZ    HZ2    sing N N 338 
LYS NZ    HZ3    sing N N 339 
LYS OXT   HXT    sing N N 340 
MET N     CA     sing N N 341 
MET N     H      sing N N 342 
MET N     H2     sing N N 343 
MET CA    C      sing N N 344 
MET CA    CB     sing N N 345 
MET CA    HA     sing N N 346 
MET C     O      doub N N 347 
MET C     OXT    sing N N 348 
MET CB    CG     sing N N 349 
MET CB    HB2    sing N N 350 
MET CB    HB3    sing N N 351 
MET CG    SD     sing N N 352 
MET CG    HG2    sing N N 353 
MET CG    HG3    sing N N 354 
MET SD    CE     sing N N 355 
MET CE    HE1    sing N N 356 
MET CE    HE2    sing N N 357 
MET CE    HE3    sing N N 358 
MET OXT   HXT    sing N N 359 
PHE N     CA     sing N N 360 
PHE N     H      sing N N 361 
PHE N     H2     sing N N 362 
PHE CA    C      sing N N 363 
PHE CA    CB     sing N N 364 
PHE CA    HA     sing N N 365 
PHE C     O      doub N N 366 
PHE C     OXT    sing N N 367 
PHE CB    CG     sing N N 368 
PHE CB    HB2    sing N N 369 
PHE CB    HB3    sing N N 370 
PHE CG    CD1    doub Y N 371 
PHE CG    CD2    sing Y N 372 
PHE CD1   CE1    sing Y N 373 
PHE CD1   HD1    sing N N 374 
PHE CD2   CE2    doub Y N 375 
PHE CD2   HD2    sing N N 376 
PHE CE1   CZ     doub Y N 377 
PHE CE1   HE1    sing N N 378 
PHE CE2   CZ     sing Y N 379 
PHE CE2   HE2    sing N N 380 
PHE CZ    HZ     sing N N 381 
PHE OXT   HXT    sing N N 382 
PRO N     CA     sing N N 383 
PRO N     CD     sing N N 384 
PRO N     H      sing N N 385 
PRO CA    C      sing N N 386 
PRO CA    CB     sing N N 387 
PRO CA    HA     sing N N 388 
PRO C     O      doub N N 389 
PRO C     OXT    sing N N 390 
PRO CB    CG     sing N N 391 
PRO CB    HB2    sing N N 392 
PRO CB    HB3    sing N N 393 
PRO CG    CD     sing N N 394 
PRO CG    HG2    sing N N 395 
PRO CG    HG3    sing N N 396 
PRO CD    HD2    sing N N 397 
PRO CD    HD3    sing N N 398 
PRO OXT   HXT    sing N N 399 
SER N     CA     sing N N 400 
SER N     H      sing N N 401 
SER N     H2     sing N N 402 
SER CA    C      sing N N 403 
SER CA    CB     sing N N 404 
SER CA    HA     sing N N 405 
SER C     O      doub N N 406 
SER C     OXT    sing N N 407 
SER CB    OG     sing N N 408 
SER CB    HB2    sing N N 409 
SER CB    HB3    sing N N 410 
SER OG    HG     sing N N 411 
SER OXT   HXT    sing N N 412 
SO4 S     O1     doub N N 413 
SO4 S     O2     doub N N 414 
SO4 S     O3     sing N N 415 
SO4 S     O4     sing N N 416 
THR N     CA     sing N N 417 
THR N     H      sing N N 418 
THR N     H2     sing N N 419 
THR CA    C      sing N N 420 
THR CA    CB     sing N N 421 
THR CA    HA     sing N N 422 
THR C     O      doub N N 423 
THR C     OXT    sing N N 424 
THR CB    OG1    sing N N 425 
THR CB    CG2    sing N N 426 
THR CB    HB     sing N N 427 
THR OG1   HG1    sing N N 428 
THR CG2   HG21   sing N N 429 
THR CG2   HG22   sing N N 430 
THR CG2   HG23   sing N N 431 
THR OXT   HXT    sing N N 432 
TRP N     CA     sing N N 433 
TRP N     H      sing N N 434 
TRP N     H2     sing N N 435 
TRP CA    C      sing N N 436 
TRP CA    CB     sing N N 437 
TRP CA    HA     sing N N 438 
TRP C     O      doub N N 439 
TRP C     OXT    sing N N 440 
TRP CB    CG     sing N N 441 
TRP CB    HB2    sing N N 442 
TRP CB    HB3    sing N N 443 
TRP CG    CD1    doub Y N 444 
TRP CG    CD2    sing Y N 445 
TRP CD1   NE1    sing Y N 446 
TRP CD1   HD1    sing N N 447 
TRP CD2   CE2    doub Y N 448 
TRP CD2   CE3    sing Y N 449 
TRP NE1   CE2    sing Y N 450 
TRP NE1   HE1    sing N N 451 
TRP CE2   CZ2    sing Y N 452 
TRP CE3   CZ3    doub Y N 453 
TRP CE3   HE3    sing N N 454 
TRP CZ2   CH2    doub Y N 455 
TRP CZ2   HZ2    sing N N 456 
TRP CZ3   CH2    sing Y N 457 
TRP CZ3   HZ3    sing N N 458 
TRP CH2   HH2    sing N N 459 
TRP OXT   HXT    sing N N 460 
TYR N     CA     sing N N 461 
TYR N     H      sing N N 462 
TYR N     H2     sing N N 463 
TYR CA    C      sing N N 464 
TYR CA    CB     sing N N 465 
TYR CA    HA     sing N N 466 
TYR C     O      doub N N 467 
TYR C     OXT    sing N N 468 
TYR CB    CG     sing N N 469 
TYR CB    HB2    sing N N 470 
TYR CB    HB3    sing N N 471 
TYR CG    CD1    doub Y N 472 
TYR CG    CD2    sing Y N 473 
TYR CD1   CE1    sing Y N 474 
TYR CD1   HD1    sing N N 475 
TYR CD2   CE2    doub Y N 476 
TYR CD2   HD2    sing N N 477 
TYR CE1   CZ     doub Y N 478 
TYR CE1   HE1    sing N N 479 
TYR CE2   CZ     sing Y N 480 
TYR CE2   HE2    sing N N 481 
TYR CZ    OH     sing N N 482 
TYR OH    HH     sing N N 483 
TYR OXT   HXT    sing N N 484 
VAL N     CA     sing N N 485 
VAL N     H      sing N N 486 
VAL N     H2     sing N N 487 
VAL CA    C      sing N N 488 
VAL CA    CB     sing N N 489 
VAL CA    HA     sing N N 490 
VAL C     O      doub N N 491 
VAL C     OXT    sing N N 492 
VAL CB    CG1    sing N N 493 
VAL CB    CG2    sing N N 494 
VAL CB    HB     sing N N 495 
VAL CG1   HG11   sing N N 496 
VAL CG1   HG12   sing N N 497 
VAL CG1   HG13   sing N N 498 
VAL CG2   HG21   sing N N 499 
VAL CG2   HG22   sing N N 500 
VAL CG2   HG23   sing N N 501 
VAL OXT   HXT    sing N N 502 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Ministerio de Ciencia e Innovacion (MCIN)' Spain TED2021-130803B-I00            1 
'Other government'                          ?     'Biologia Estructural E35_23R' 2 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   5OC1 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9AVH 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.017846 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.012085 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.008559 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
C 6  6  2.3103  20.8439 1.0201 10.2075 1.5888 0.5687  0.8651 51.6512 0.2156   
H 1  1  0.4930  10.5109 0.3229 26.1257 0.1402 3.1424  0.0408 57.7997 0.0030   
N 7  7  12.2220 0.0057  3.1346 9.8933  2.0141 28.9975 1.1672 0.5826  -11.5379 
O 8  8  3.0487  13.2771 2.2870 5.7011  1.5464 0.3239  0.8671 32.9089 0.2508   
P 15 15 6.4348  1.9067  4.1793 27.1570 1.7801 0.5260  1.4909 68.1645 1.2679   
S 16 16 6.9054  1.4679  5.2035 22.2151 1.4379 0.2536  1.5863 56.1720 1.0495   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
_atom_site.calc_flag 
ATOM   1    N N     . THR A 1 3   ? 12.522  8.844   -44.825 1.000 53.507  0 2    THR A N     1 ? 
ATOM   2    C CA    . THR A 1 3   ? 12.318  10.124  -45.556 1.000 49.711  0 2    THR A CA    1 ? 
ATOM   3    C C     . THR A 1 3   ? 10.990  10.105  -46.323 1.000 40.940  0 2    THR A C     1 ? 
ATOM   4    O O     . THR A 1 3   ? 10.462  9.069   -46.723 1.000 40.562  0 2    THR A O     1 ? 
ATOM   5    C CB    . THR A 1 3   ? 13.482  10.434  -46.503 1.000 55.057  0 2    THR A CB    1 ? 
ATOM   6    O OG1   . THR A 1 3   ? 13.362  9.427   -47.502 1.000 57.091  0 2    THR A OG1   1 ? 
ATOM   7    C CG2   . THR A 1 3   ? 14.848  10.409  -45.834 1.000 54.094  0 2    THR A CG2   1 ? 
ATOM   8    N N     . PHE A 1 4   ? 10.498  11.320  -46.566 1.000 34.507  0 3    PHE A N     1 ? 
ATOM   9    C CA    . PHE A 1 4   ? 9.163   11.589  -47.062 1.000 26.332  0 3    PHE A CA    1 ? 
ATOM   10   C C     . PHE A 1 4   ? 9.285   12.395  -48.339 1.000 25.630  0 3    PHE A C     1 ? 
ATOM   11   O O     . PHE A 1 4   ? 10.265  13.094  -48.475 1.000 26.954  0 3    PHE A O     1 ? 
ATOM   12   C CB    . PHE A 1 4   ? 8.579   12.464  -45.959 1.000 24.801  0 3    PHE A CB    1 ? 
ATOM   13   C CG    . PHE A 1 4   ? 8.338   11.721  -44.655 1.000 25.406  0 3    PHE A CG    1 ? 
ATOM   14   C CD1   . PHE A 1 4   ? 7.225   10.912  -44.510 1.000 26.475  0 3    PHE A CD1   1 ? 
ATOM   15   C CD2   . PHE A 1 4   ? 9.166   11.887  -43.561 1.000 27.815  0 3    PHE A CD2   1 ? 
ATOM   16   C CE1   . PHE A 1 4   ? 6.965   10.257  -43.312 1.000 28.963  0 3    PHE A CE1   1 ? 
ATOM   17   C CE2   . PHE A 1 4   ? 8.912   11.213  -42.375 1.000 26.396  0 3    PHE A CE2   1 ? 
ATOM   18   C CZ    . PHE A 1 4   ? 7.832   10.393  -42.262 1.000 24.972  0 3    PHE A CZ    1 ? 
ATOM   19   N N     . PHE A 1 5   ? 8.271   12.421  -49.189 1.000 26.370  0 4    PHE A N     1 ? 
ATOM   20   C CA    . PHE A 1 5   ? 8.253   13.405  -50.259 1.000 25.455  0 4    PHE A CA    1 ? 
ATOM   21   C C     . PHE A 1 5   ? 7.885   14.770  -49.689 1.000 24.826  0 4    PHE A C     1 ? 
ATOM   22   O O     . PHE A 1 5   ? 7.115   14.818  -48.738 1.000 22.674  0 4    PHE A O     1 ? 
ATOM   23   C CB    . PHE A 1 5   ? 7.216   12.939  -51.272 1.000 25.979  0 4    PHE A CB    1 ? 
ATOM   24   C CG    . PHE A 1 5   ? 7.530   11.604  -51.928 1.000 28.728  0 4    PHE A CG    1 ? 
ATOM   25   C CD1   . PHE A 1 5   ? 8.626   11.465  -52.766 1.000 32.930  0 4    PHE A CD1   1 ? 
ATOM   26   C CD2   . PHE A 1 5   ? 6.699   10.506  -51.752 1.000 34.827  0 4    PHE A CD2   1 ? 
ATOM   27   C CE1   . PHE A 1 5   ? 8.875   10.262  -53.419 1.000 34.816  0 4    PHE A CE1   1 ? 
ATOM   28   C CE2   . PHE A 1 5   ? 6.958   9.305   -52.403 1.000 36.259  0 4    PHE A CE2   1 ? 
ATOM   29   C CZ    . PHE A 1 5   ? 8.059   9.184   -53.215 1.000 35.513  0 4    PHE A CZ    1 ? 
ATOM   30   N N     . THR A 1 6   ? 8.392   15.862  -50.290 1.000 22.722  0 5    THR A N     1 ? 
ATOM   31   C CA    . THR A 1 6   ? 8.069   17.217  -49.842 1.000 24.632  0 5    THR A CA    1 ? 
ATOM   32   C C     . THR A 1 6   ? 7.417   18.044  -50.951 1.000 24.693  0 5    THR A C     1 ? 
ATOM   33   O O     . THR A 1 6   ? 7.003   19.177  -50.707 1.000 22.503  0 5    THR A O     1 ? 
ATOM   34   C CB    . THR A 1 6   ? 9.308   17.920  -49.270 1.000 27.030  0 5    THR A CB    1 ? 
ATOM   35   O OG1   . THR A 1 6   ? 10.338  17.868  -50.246 1.000 27.442  0 5    THR A OG1   1 ? 
ATOM   36   C CG2   . THR A 1 6   ? 9.852   17.231  -48.030 1.000 30.154  0 5    THR A CG2   1 ? 
ATOM   37   N N     . ASP A 1 7   ? 7.299   17.478  -52.154 1.000 27.646  0 6    ASP A N     1 ? 
ATOM   38   C CA    . ASP A 1 7   ? 6.709   18.186  -53.273 1.000 32.414  0 6    ASP A CA    1 ? 
ATOM   39   C C     . ASP A 1 7   ? 6.047   17.206  -54.239 1.000 28.703  0 6    ASP A C     1 ? 
ATOM   40   O O     . ASP A 1 7   ? 6.543   16.102  -54.477 1.000 30.000  0 6    ASP A O     1 ? 
ATOM   41   C CB    . ASP A 1 7   ? 7.719   19.009  -54.051 1.000 36.351  0 6    ASP A CB    1 ? 
ATOM   42   C CG    . ASP A 1 7   ? 7.068   20.114  -54.880 1.000 46.291  0 6    ASP A CG    1 ? 
ATOM   43   O OD1   . ASP A 1 7   ? 6.856   21.202  -54.299 1.000 48.996  0 6    ASP A OD1   1 ? 
ATOM   44   O OD2   . ASP A 1 7   ? 6.727   19.862  -56.079 1.000 42.846  0 6    ASP A OD2   1 ? 
ATOM   45   N N     . ALA A 1 8   ? 4.964   17.695  -54.838 1.000 29.796  0 7    ALA A N     1 ? 
ATOM   46   C CA    . ALA A 1 8   ? 4.115   16.947  -55.750 1.000 31.594  0 7    ALA A CA    1 ? 
ATOM   47   C C     . ALA A 1 8   ? 4.926   16.385  -56.918 1.000 31.321  0 7    ALA A C     1 ? 
ATOM   48   O O     . ALA A 1 8   ? 4.608   15.303  -57.408 1.000 29.166  0 7    ALA A O     1 ? 
ATOM   49   C CB    . ALA A 1 8   ? 3.010   17.838  -56.242 1.000 31.819  0 7    ALA A CB    1 ? 
ATOM   50   N N     . SER A 1 9   ? 5.971   17.123  -57.334 1.000 32.664  0 8    SER A N     1 ? 
ATOM   51   C CA    . SER A 1 9   ? 6.773   16.748  -58.491 1.000 34.725  0 8    SER A CA    1 ? 
ATOM   52   C C     . SER A 1 9   ? 7.580   15.480  -58.212 1.000 33.928  0 8    SER A C     1 ? 
ATOM   53   O O     . SER A 1 9   ? 8.049   14.838  -59.149 1.000 36.836  0 8    SER A O     1 ? 
ATOM   54   C CB    . SER A 1 9   ? 7.685   17.883  -58.919 1.000 38.027  0 8    SER A CB    1 ? 
ATOM   55   O OG    . SER A 1 9   ? 8.698   18.097  -57.939 1.000 41.097  0 8    SER A OG    1 ? 
ATOM   56   N N     . GLN A 1 10  ? 7.719   15.098  -56.936 1.000 29.981  0 9    GLN A N     1 ? 
ATOM   57   C CA    . GLN A 1 10  ? 8.448   13.885  -56.580 1.000 27.149  0 9    GLN A CA    1 ? 
ATOM   58   C C     . GLN A 1 10  ? 7.554   12.641  -56.605 1.000 26.976  0 9    GLN A C     1 ? 
ATOM   59   O O     . GLN A 1 10  ? 8.076   11.540  -56.552 1.000 28.934  0 9    GLN A O     1 ? 
ATOM   60   C CB    . GLN A 1 10  ? 9.068   13.965  -55.189 1.000 29.879  0 9    GLN A CB    1 ? 
ATOM   61   C CG    . GLN A 1 10  ? 10.031  15.130  -54.943 1.000 31.797  0 9    GLN A CG    1 ? 
ATOM   62   C CD    . GLN A 1 10  ? 10.412  15.242  -53.476 1.000 34.803  0 9    GLN A CD    1 ? 
ATOM   63   O OE1   . GLN A 1 10  ? 9.558   15.354  -52.611 1.000 31.127  0 9    GLN A OE1   1 ? 
ATOM   64   N NE2   . GLN A 1 10  ? 11.688  15.161  -53.143 1.000 40.200  0 9    GLN A NE2   1 ? 
ATOM   65   N N     . LEU A 1 11  ? 6.224   12.784  -56.646 1.000 26.456  0 10   LEU A N     1 ? 
ATOM   66   C CA    . LEU A 1 11  ? 5.343   11.633  -56.448 1.000 26.834  0 10   LEU A CA    1 ? 
ATOM   67   C C     . LEU A 1 11  ? 5.448   10.674  -57.627 1.000 30.519  0 10   LEU A C     1 ? 
ATOM   68   O O     . LEU A 1 11  ? 5.572   11.116  -58.751 1.000 28.602  0 10   LEU A O     1 ? 
ATOM   69   C CB    . LEU A 1 11  ? 3.895   12.073  -56.293 1.000 25.525  0 10   LEU A CB    1 ? 
ATOM   70   C CG    . LEU A 1 11  ? 3.557   12.941  -55.074 1.000 28.432  0 10   LEU A CG    1 ? 
ATOM   71   C CD1   . LEU A 1 11  ? 2.171   13.503  -55.220 1.000 30.934  0 10   LEU A CD1   1 ? 
ATOM   72   C CD2   . LEU A 1 11  ? 3.686   12.179  -53.808 1.000 30.608  0 10   LEU A CD2   1 ? 
ATOM   73   N N     . PRO A 1 12  ? 5.263   9.352   -57.444 1.000 32.332  0 11   PRO A N     1 ? 
ATOM   74   C CA    . PRO A 1 12  ? 5.312   8.434   -58.581 1.000 33.712  0 11   PRO A CA    1 ? 
ATOM   75   C C     . PRO A 1 12  ? 4.046   8.403   -59.441 1.000 34.183  0 11   PRO A C     1 ? 
ATOM   76   O O     . PRO A 1 12  ? 4.086   7.879   -60.549 1.000 38.708  0 11   PRO A O     1 ? 
ATOM   77   C CB    . PRO A 1 12  ? 5.587   7.098   -57.863 1.000 35.608  0 11   PRO A CB    1 ? 
ATOM   78   C CG    . PRO A 1 12  ? 4.773   7.197   -56.600 1.000 35.909  0 11   PRO A CG    1 ? 
ATOM   79   C CD    . PRO A 1 12  ? 4.957   8.671   -56.170 1.000 36.030  0 11   PRO A CD    1 ? 
ATOM   80   N N     . ALA A 1 13  ? 2.944   8.979   -58.950 1.000 28.388  0 12   ALA A N     1 ? 
ATOM   81   C CA    . ALA A 1 13  ? 1.643   8.945   -59.604 1.000 27.113  0 12   ALA A CA    1 ? 
ATOM   82   C C     . ALA A 1 13  ? 0.824   10.156  -59.165 1.000 27.389  0 12   ALA A C     1 ? 
ATOM   83   O O     . ALA A 1 13  ? 1.135   10.746  -58.118 1.000 26.951  0 12   ALA A O     1 ? 
ATOM   84   C CB    . ALA A 1 13  ? 0.905   7.664   -59.225 1.000 28.053  0 12   ALA A CB    1 ? 
ATOM   85   N N     . THR A 1 14  ? -0.277  10.432  -59.890 1.000 24.646  0 13   THR A N     1 ? 
ATOM   86   C CA    . THR A 1 14  ? -1.250  11.435  -59.490 1.000 26.830  0 13   THR A CA    1 ? 
ATOM   87   C C     . THR A 1 14  ? -2.593  10.788  -59.167 1.000 26.892  0 13   THR A C     1 ? 
ATOM   88   O O     . THR A 1 14  ? -3.526  11.509  -58.827 1.000 25.700  0 13   THR A O     1 ? 
ATOM   89   C CB    . THR A 1 14  ? -1.446  12.490  -60.580 1.000 31.113  0 13   THR A CB    1 ? 
ATOM   90   O OG1   . THR A 1 14  ? -2.135  11.798  -61.616 1.000 30.728  0 13   THR A OG1   1 ? 
ATOM   91   C CG2   . THR A 1 14  ? -0.135  13.101  -61.034 1.000 36.923  0 13   THR A CG2   1 ? 
ATOM   92   N N     . VAL A 1 15  ? -2.666  9.448   -59.256 1.000 23.938  0 14   VAL A N     1 ? 
ATOM   93   C CA    . VAL A 1 15  ? -3.885  8.695   -59.007 1.000 24.312  0 14   VAL A CA    1 ? 
ATOM   94   C C     . VAL A 1 15  ? -3.555  7.549   -58.049 1.000 22.532  0 14   VAL A C     1 ? 
ATOM   95   O O     . VAL A 1 15  ? -2.579  6.831   -58.236 1.000 22.581  0 14   VAL A O     1 ? 
ATOM   96   C CB    . VAL A 1 15  ? -4.545  8.147   -60.288 1.000 26.653  0 14   VAL A CB    1 ? 
ATOM   97   C CG1   . VAL A 1 15  ? -5.856  7.443   -59.993 1.000 27.178  0 14   VAL A CG1   1 ? 
ATOM   98   C CG2   . VAL A 1 15  ? -4.793  9.251   -61.316 1.000 28.871  0 14   VAL A CG2   1 ? 
ATOM   99   N N     . TYR A 1 16  ? -4.395  7.394   -57.032 1.000 20.707  0 15   TYR A N     1 ? 
ATOM   100  C CA    . TYR A 1 16  ? -4.205  6.423   -55.973 1.000 19.461  0 15   TYR A CA    1 ? 
ATOM   101  C C     . TYR A 1 16  ? -5.568  5.842   -55.622 1.000 19.473  0 15   TYR A C     1 ? 
ATOM   102  O O     . TYR A 1 16  ? -6.607  6.441   -55.883 1.000 18.521  0 15   TYR A O     1 ? 
ATOM   103  C CB    . TYR A 1 16  ? -3.583  7.028   -54.700 1.000 20.596  0 15   TYR A CB    1 ? 
ATOM   104  C CG    . TYR A 1 16  ? -2.243  7.689   -54.933 1.000 22.032  0 15   TYR A CG    1 ? 
ATOM   105  C CD1   . TYR A 1 16  ? -2.174  8.971   -55.471 1.000 21.366  0 15   TYR A CD1   1 ? 
ATOM   106  C CD2   . TYR A 1 16  ? -1.056  7.011   -54.677 1.000 21.916  0 15   TYR A CD2   1 ? 
ATOM   107  C CE1   . TYR A 1 16  ? -0.953  9.556   -55.723 1.000 20.769  0 15   TYR A CE1   1 ? 
ATOM   108  C CE2   . TYR A 1 16  ? 0.175   7.596   -54.921 1.000 21.567  0 15   TYR A CE2   1 ? 
ATOM   109  C CZ    . TYR A 1 16  ? 0.212   8.869   -55.461 1.000 20.576  0 15   TYR A CZ    1 ? 
ATOM   110  O OH    . TYR A 1 16  ? 1.393   9.470   -55.725 1.000 23.273  0 15   TYR A OH    1 ? 
ATOM   111  N N     . ASP A 1 17  ? -5.569  4.626   -55.032 1.000 19.594  0 16   ASP A N     1 ? 
ATOM   112  C CA    . ASP A 1 17  ? -6.814  4.038   -54.562 1.000 20.292  0 16   ASP A CA    1 ? 
ATOM   113  C C     . ASP A 1 17  ? -7.435  4.935   -53.491 1.000 19.338  0 16   ASP A C     1 ? 
ATOM   114  O O     . ASP A 1 17  ? -8.629  5.225   -53.508 1.000 18.071  0 16   ASP A O     1 ? 
ATOM   115  C CB    . ASP A 1 17  ? -6.602  2.625   -54.036 1.000 20.348  0 16   ASP A CB    1 ? 
ATOM   116  C CG    . ASP A 1 17  ? -6.234  1.581   -55.086 1.000 23.646  0 16   ASP A CG    1 ? 
ATOM   117  O OD1   . ASP A 1 17  ? -6.504  1.810   -56.261 1.000 25.145  0 16   ASP A OD1   1 ? 
ATOM   118  O OD2   . ASP A 1 17  ? -5.593  0.614   -54.735 1.000 21.503  0 16   ASP A OD2   1 ? 
ATOM   119  N N     . PHE A 1 18  ? -6.626  5.292   -52.497 1.000 18.760  0 17   PHE A N     1 ? 
ATOM   120  C CA    . PHE A 1 18  ? -7.092  6.143   -51.405 1.000 18.638  0 17   PHE A CA    1 ? 
ATOM   121  C C     . PHE A 1 18  ? -6.132  7.307   -51.213 1.000 17.918  0 17   PHE A C     1 ? 
ATOM   122  O O     . PHE A 1 18  ? -4.921  7.167   -51.393 1.000 17.837  0 17   PHE A O     1 ? 
ATOM   123  C CB    . PHE A 1 18  ? -7.209  5.382   -50.080 1.000 18.362  0 17   PHE A CB    1 ? 
ATOM   124  C CG    . PHE A 1 18  ? -8.202  4.244   -50.159 1.000 19.387  0 17   PHE A CG    1 ? 
ATOM   125  C CD1   . PHE A 1 18  ? -7.806  2.971   -50.591 1.000 19.289  0 17   PHE A CD1   1 ? 
ATOM   126  C CD2   . PHE A 1 18  ? -9.538  4.461   -49.849 1.000 19.400  0 17   PHE A CD2   1 ? 
ATOM   127  C CE1   . PHE A 1 18  ? -8.732  1.952   -50.640 1.000 20.356  0 17   PHE A CE1   1 ? 
ATOM   128  C CE2   . PHE A 1 18  ? -10.476 3.445   -49.948 1.000 18.857  0 17   PHE A CE2   1 ? 
ATOM   129  C CZ    . PHE A 1 18  ? -10.068 2.186   -50.322 1.000 20.363  0 17   PHE A CZ    1 ? 
ATOM   130  N N     . ILE A 1 19  ? -6.702  8.451   -50.849 1.000 17.448  0 18   ILE A N     1 ? 
ATOM   131  C CA    . ILE A 1 19  ? -5.932  9.567   -50.342 1.000 19.815  0 18   ILE A CA    1 ? 
ATOM   132  C C     . ILE A 1 19  ? -6.387  9.834   -48.913 1.000 17.397  0 18   ILE A C     1 ? 
ATOM   133  O O     . ILE A 1 19  ? -7.588  9.941   -48.641 1.000 19.794  0 18   ILE A O     1 ? 
ATOM   134  C CB    . ILE A 1 19  ? -6.085  10.802  -51.240 1.000 21.488  0 18   ILE A CB    1 ? 
ATOM   135  C CG1   . ILE A 1 19  ? -5.598  10.506  -52.648 1.000 23.546  0 18   ILE A CG1   1 ? 
ATOM   136  C CG2   . ILE A 1 19  ? -5.358  12.018  -50.653 1.000 20.058  0 18   ILE A CG2   1 ? 
ATOM   137  C CD1   . ILE A 1 19  ? -6.061  11.548  -53.628 1.000 25.339  0 18   ILE A CD1   1 ? 
ATOM   138  N N     . VAL A 1 20  ? -5.425  9.844   -48.004 1.000 17.984  0 19   VAL A N     1 ? 
ATOM   139  C CA    . VAL A 1 20  ? -5.678  10.159  -46.595 1.000 17.002  0 19   VAL A CA    1 ? 
ATOM   140  C C     . VAL A 1 20  ? -5.032  11.500  -46.311 1.000 17.326  0 19   VAL A C     1 ? 
ATOM   141  O O     . VAL A 1 20  ? -3.836  11.703  -46.567 1.000 18.114  0 19   VAL A O     1 ? 
ATOM   142  C CB    . VAL A 1 20  ? -5.099  9.106   -45.638 1.000 18.931  0 19   VAL A CB    1 ? 
ATOM   143  C CG1   . VAL A 1 20  ? -5.363  9.444   -44.171 1.000 19.040  0 19   VAL A CG1   1 ? 
ATOM   144  C CG2   . VAL A 1 20  ? -5.574  7.710   -45.999 1.000 20.846  0 19   VAL A CG2   1 ? 
ATOM   145  N N     . VAL A 1 21  ? -5.830  12.408  -45.748 1.000 18.373  0 20   VAL A N     1 ? 
ATOM   146  C CA    . VAL A 1 21  ? -5.351  13.734  -45.441 1.000 16.661  0 20   VAL A CA    1 ? 
ATOM   147  C C     . VAL A 1 21  ? -5.103  13.825  -43.941 1.000 16.391  0 20   VAL A C     1 ? 
ATOM   148  O O     . VAL A 1 21  ? -6.056  13.736  -43.196 1.000 18.654  0 20   VAL A O     1 ? 
ATOM   149  C CB    . VAL A 1 21  ? -6.392  14.786  -45.854 1.000 18.324  0 20   VAL A CB    1 ? 
ATOM   150  C CG1   . VAL A 1 21  ? -5.841  16.173  -45.536 1.000 18.762  0 20   VAL A CG1   1 ? 
ATOM   151  C CG2   . VAL A 1 21  ? -6.759  14.608  -47.318 1.000 18.576  0 20   VAL A CG2   1 ? 
ATOM   152  N N     . GLY A 1 22  ? -3.843  13.981  -43.533 1.000 17.936  0 21   GLY A N     1 ? 
ATOM   153  C CA    . GLY A 1 22  ? -3.488  14.181  -42.130 1.000 18.577  0 21   GLY A CA    1 ? 
ATOM   154  C C     . GLY A 1 22  ? -2.778  12.958  -41.568 1.000 18.089  0 21   GLY A C     1 ? 
ATOM   155  O O     . GLY A 1 22  ? -3.428  11.934  -41.319 1.000 20.266  0 21   GLY A O     1 ? 
ATOM   156  N N     . ALA A 1 23  ? -1.441  13.056  -41.412 1.000 16.225  0 22   ALA A N     1 ? 
ATOM   157  C CA    . ALA A 1 23  ? -0.617  11.974  -40.884 1.000 14.816  0 22   ALA A CA    1 ? 
ATOM   158  C C     . ALA A 1 23  ? -0.585  12.035  -39.360 1.000 16.833  0 22   ALA A C     1 ? 
ATOM   159  O O     . ALA A 1 23  ? 0.481   12.066  -38.755 1.000 17.124  0 22   ALA A O     1 ? 
ATOM   160  C CB    . ALA A 1 23  ? 0.763   12.061  -41.437 1.000 15.933  0 22   ALA A CB    1 ? 
ATOM   161  N N     . GLY A 1 24  ? -1.769  12.026  -38.760 1.000 16.553  0 23   GLY A N     1 ? 
ATOM   162  C CA    . GLY A 1 24  ? -1.897  12.284  -37.342 1.000 17.604  0 23   GLY A CA    1 ? 
ATOM   163  C C     . GLY A 1 24  ? -2.293  11.023  -36.588 1.000 18.244  0 23   GLY A C     1 ? 
ATOM   164  O O     . GLY A 1 24  ? -2.007  9.898   -37.004 1.000 16.645  0 23   GLY A O     1 ? 
ATOM   165  N N     . ASN A 1 25  ? -2.959  11.240  -35.463 1.000 20.112  0 24   ASN A N     1 ? 
ATOM   166  C CA    . ASN A 1 25  ? -3.317  10.175  -34.532 1.000 19.969  0 24   ASN A CA    1 ? 
ATOM   167  C C     . ASN A 1 25  ? -4.112  9.090   -35.256 1.000 20.285  0 24   ASN A C     1 ? 
ATOM   168  O O     . ASN A 1 25  ? -3.738  7.908   -35.183 1.000 20.668  0 24   ASN A O     1 ? 
ATOM   169  C CB    . ASN A 1 25  ? -4.043  10.806  -33.353 1.000 18.933  0 24   ASN A CB    1 ? 
ATOM   170  C CG    . ASN A 1 25  ? -4.378  9.889   -32.205 1.000 20.637  0 24   ASN A CG    1 ? 
ATOM   171  O OD1   . ASN A 1 25  ? -4.586  10.403  -31.107 1.000 21.246  0 24   ASN A OD1   1 ? 
ATOM   172  N ND2   . ASN A 1 25  ? -4.422  8.579   -32.408 1.000 21.026  0 24   ASN A ND2   1 ? 
ATOM   173  N N     . ALA A 1 26  ? -5.153  9.502   -36.009 1.000 18.506  0 25   ALA A N     1 ? 
ATOM   174  C CA    . ALA A 1 26  ? -6.009  8.573   -36.740 1.000 16.813  0 25   ALA A CA    1 ? 
ATOM   175  C C     . ALA A 1 26  ? -5.477  8.270   -38.136 1.000 16.965  0 25   ALA A C     1 ? 
ATOM   176  O O     . ALA A 1 26  ? -5.546  7.118   -38.618 1.000 16.685  0 25   ALA A O     1 ? 
ATOM   177  C CB    . ALA A 1 26  ? -7.422  9.122   -36.840 1.000 16.310  0 25   ALA A CB    1 ? 
ATOM   178  N N     . GLY A 1 27  ? -4.972  9.298   -38.803 1.000 17.763  0 26   GLY A N     1 ? 
ATOM   179  C CA    . GLY A 1 27  ? -4.649  9.179   -40.218 1.000 16.159  0 26   GLY A CA    1 ? 
ATOM   180  C C     . GLY A 1 27  ? -3.549  8.151   -40.447 1.000 16.352  0 26   GLY A C     1 ? 
ATOM   181  O O     . GLY A 1 27  ? -3.541  7.450   -41.466 1.000 16.114  0 26   GLY A O     1 ? 
ATOM   182  N N     . ASN A 1 28  ? -2.590  8.098   -39.533 1.000 16.828  0 27   ASN A N     1 ? 
ATOM   183  C CA    . ASN A 1 28  ? -1.504  7.137   -39.699 1.000 18.466  0 27   ASN A CA    1 ? 
ATOM   184  C C     . ASN A 1 28  ? -2.026  5.713   -39.521 1.000 17.885  0 27   ASN A C     1 ? 
ATOM   185  O O     . ASN A 1 28  ? -1.476  4.788   -40.117 1.000 17.668  0 27   ASN A O     1 ? 
ATOM   186  C CB    . ASN A 1 28  ? -0.348  7.374   -38.742 1.000 17.986  0 27   ASN A CB    1 ? 
ATOM   187  C CG    . ASN A 1 28  ? 0.479   8.557   -39.129 1.000 17.175  0 27   ASN A CG    1 ? 
ATOM   188  O OD1   . ASN A 1 28  ? 0.428   8.973   -40.298 1.000 18.345  0 27   ASN A OD1   1 ? 
ATOM   189  N ND2   . ASN A 1 28  ? 1.270   9.089   -38.202 1.000 15.617  0 27   ASN A ND2   1 ? 
ATOM   190  N N     . VAL A 1 29  ? -2.992  5.510   -38.616 1.000 17.828  0 28   VAL A N     1 ? 
ATOM   191  C CA    . VAL A 1 29  ? -3.670  4.222   -38.484 1.000 16.653  0 28   VAL A CA    1 ? 
ATOM   192  C C     . VAL A 1 29  ? -4.282  3.831   -39.832 1.000 17.646  0 28   VAL A C     1 ? 
ATOM   193  O O     . VAL A 1 29  ? -4.119  2.700   -40.320 1.000 14.558  0 28   VAL A O     1 ? 
ATOM   194  C CB    . VAL A 1 29  ? -4.771  4.187   -37.404 1.000 17.581  0 28   VAL A CB    1 ? 
ATOM   195  C CG1   . VAL A 1 29  ? -5.495  2.846   -37.343 1.000 18.210  0 28   VAL A CG1   1 ? 
ATOM   196  C CG2   . VAL A 1 29  ? -4.202  4.507   -36.022 1.000 18.840  0 28   VAL A CG2   1 ? 
ATOM   197  N N     . VAL A 1 30  ? -5.060  4.746   -40.411 1.000 18.024  0 29   VAL A N     1 ? 
ATOM   198  C CA    . VAL A 1 30  ? -5.726  4.434   -41.670 1.000 17.849  0 29   VAL A CA    1 ? 
ATOM   199  C C     . VAL A 1 30  ? -4.713  4.090   -42.754 1.000 19.143  0 29   VAL A C     1 ? 
ATOM   200  O O     . VAL A 1 30  ? -4.873  3.090   -43.458 1.000 19.794  0 29   VAL A O     1 ? 
ATOM   201  C CB    . VAL A 1 30  ? -6.672  5.566   -42.116 1.000 18.737  0 29   VAL A CB    1 ? 
ATOM   202  C CG1   . VAL A 1 30  ? -7.324  5.263   -43.455 1.000 21.327  0 29   VAL A CG1   1 ? 
ATOM   203  C CG2   . VAL A 1 30  ? -7.703  5.867   -41.046 1.000 19.549  0 29   VAL A CG2   1 ? 
ATOM   204  N N     . ALA A 1 31  ? -3.674  4.922   -42.934 1.000 19.076  0 30   ALA A N     1 ? 
ATOM   205  C CA    . ALA A 1 31  ? -2.705  4.695   -44.015 1.000 19.838  0 30   ALA A CA    1 ? 
ATOM   206  C C     . ALA A 1 31  ? -1.989  3.347   -43.846 1.000 18.718  0 30   ALA A C     1 ? 
ATOM   207  O O     . ALA A 1 31  ? -1.805  2.598   -44.806 1.000 19.439  0 30   ALA A O     1 ? 
ATOM   208  C CB    . ALA A 1 31  ? -1.690  5.833   -44.090 1.000 18.319  0 30   ALA A CB    1 ? 
ATOM   209  N N     . ALA A 1 32  ? -1.634  3.013   -42.605 1.000 17.319  0 31   ALA A N     1 ? 
ATOM   210  C CA    . ALA A 1 32  ? -0.951  1.759   -42.330 1.000 17.982  0 31   ALA A CA    1 ? 
ATOM   211  C C     . ALA A 1 32  ? -1.891  0.579   -42.491 1.000 18.204  0 31   ALA A C     1 ? 
ATOM   212  O O     . ALA A 1 32  ? -1.526  -0.386  -43.145 1.000 20.806  0 31   ALA A O     1 ? 
ATOM   213  C CB    . ALA A 1 32  ? -0.342  1.797   -40.948 1.000 18.465  0 31   ALA A CB    1 ? 
ATOM   214  N N     . ARG A 1 33  ? -3.109  0.665   -41.939 1.000 16.893  0 32   ARG A N     1 ? 
ATOM   215  C CA    . ARG A 1 33  ? -4.040  -0.460  -42.018 1.000 17.935  0 32   ARG A CA    1 ? 
ATOM   216  C C     . ARG A 1 33  ? -4.412  -0.761  -43.468 1.000 18.718  0 32   ARG A C     1 ? 
ATOM   217  O O     . ARG A 1 33  ? -4.474  -1.948  -43.863 1.000 19.133  0 32   ARG A O     1 ? 
ATOM   218  C CB    . ARG A 1 33  ? -5.311  -0.306  -41.187 1.000 18.528  0 32   ARG A CB    1 ? 
ATOM   219  C CG    . ARG A 1 33  ? -5.020  -0.309  -39.684 1.000 19.520  0 32   ARG A CG    1 ? 
ATOM   220  C CD    . ARG A 1 33  ? -4.338  -1.569  -39.184 1.000 19.711  0 32   ARG A CD    1 ? 
ATOM   221  N NE    . ARG A 1 33  ? -4.224  -1.614  -37.726 1.000 20.115  0 32   ARG A NE    1 ? 
ATOM   222  C CZ    . ARG A 1 33  ? -3.453  -2.414  -37.022 1.000 20.353  0 32   ARG A CZ    1 ? 
ATOM   223  N NH1   . ARG A 1 33  ? -2.598  -3.245  -37.632 1.000 19.581  0 32   ARG A NH1   1 ? 
ATOM   224  N NH2   . ARG A 1 33  ? -3.503  -2.328  -35.704 1.000 18.303  0 32   ARG A NH2   1 ? 
ATOM   225  N N     . LEU A 1 34  ? -4.692  0.294   -44.246 1.000 16.413  0 33   LEU A N     1 ? 
ATOM   226  C CA    . LEU A 1 34  ? -5.159  0.089   -45.611 1.000 18.543  0 33   LEU A CA    1 ? 
ATOM   227  C C     . LEU A 1 34  ? -4.071  -0.483  -46.512 1.000 18.879  0 33   LEU A C     1 ? 
ATOM   228  O O     . LEU A 1 34  ? -4.387  -1.106  -47.543 1.000 21.369  0 33   LEU A O     1 ? 
ATOM   229  C CB    . LEU A 1 34  ? -5.699  1.388   -46.205 1.000 19.537  0 33   LEU A CB    1 ? 
ATOM   230  C CG    . LEU A 1 34  ? -7.004  1.921   -45.609 1.000 21.761  0 33   LEU A CG    1 ? 
ATOM   231  C CD1   . LEU A 1 34  ? -7.453  3.157   -46.424 1.000 22.531  0 33   LEU A CD1   1 ? 
ATOM   232  C CD2   . LEU A 1 34  ? -8.080  0.850   -45.555 1.000 22.673  0 33   LEU A CD2   1 ? 
ATOM   233  N N     . THR A 1 35  ? -2.795  -0.241  -46.202 1.000 18.879  0 34   THR A N     1 ? 
ATOM   234  C CA    . THR A 1 35  ? -1.721  -0.704  -47.073 1.000 17.172  0 34   THR A CA    1 ? 
ATOM   235  C C     . THR A 1 35  ? -1.210  -2.100  -46.695 1.000 18.649  0 34   THR A C     1 ? 
ATOM   236  O O     . THR A 1 35  ? -0.231  -2.559  -47.274 1.000 18.320  0 34   THR A O     1 ? 
ATOM   237  C CB    . THR A 1 35  ? -0.576  0.314   -47.080 1.000 18.638  0 34   THR A CB    1 ? 
ATOM   238  O OG1   . THR A 1 35  ? -0.097  0.616   -45.772 1.000 18.966  0 34   THR A OG1   1 ? 
ATOM   239  C CG2   . THR A 1 35  ? -1.006  1.554   -47.824 1.000 21.014  0 34   THR A CG2   1 ? 
ATOM   240  N N     . GLU A 1 36  ? -1.828  -2.764  -45.713 1.000 18.006  0 35   GLU A N     1 ? 
ATOM   241  C CA    . GLU A 1 36  ? -1.360  -4.050  -45.197 1.000 19.054  0 35   GLU A CA    1 ? 
ATOM   242  C C     . GLU A 1 36  ? -1.433  -5.184  -46.228 1.000 20.951  0 35   GLU A C     1 ? 
ATOM   243  O O     . GLU A 1 36  ? -0.673  -6.150  -46.120 1.000 21.662  0 35   GLU A O     1 ? 
ATOM   244  C CB    . GLU A 1 36  ? -2.123  -4.460  -43.939 1.000 20.885  0 35   GLU A CB    1 ? 
ATOM   245  C CG    . GLU A 1 36  ? -1.660  -3.722  -42.688 1.000 20.190  0 35   GLU A CG    1 ? 
ATOM   246  C CD    . GLU A 1 36  ? -2.512  -3.955  -41.442 1.000 23.462  0 35   GLU A CD    1 ? 
ATOM   247  O OE1   . GLU A 1 36  ? -3.669  -4.435  -41.571 1.000 21.564  0 35   GLU A OE1   1 ? 
ATOM   248  O OE2   . GLU A 1 36  ? -2.057  -3.544  -40.335 1.000 22.299  0 35   GLU A OE2   1 ? 
ATOM   249  N N     . ASP A 1 37  ? -2.230  -5.022  -47.288 1.000 19.487  0 36   ASP A N     1 ? 
ATOM   250  C CA    . ASP A 1 37  ? -2.324  -6.030  -48.338 1.000 20.340  0 36   ASP A CA    1 ? 
ATOM   251  C C     . ASP A 1 37  ? -1.174  -5.958  -49.341 1.000 22.291  0 36   ASP A C     1 ? 
ATOM   252  O O     . ASP A 1 37  ? -1.074  -6.823  -50.204 1.000 21.423  0 36   ASP A O     1 ? 
ATOM   253  C CB    . ASP A 1 37  ? -3.665  -5.941  -49.053 1.000 21.931  0 36   ASP A CB    1 ? 
ATOM   254  C CG    . ASP A 1 37  ? -3.967  -4.614  -49.731 1.000 22.351  0 36   ASP A CG    1 ? 
ATOM   255  O OD1   . ASP A 1 37  ? -3.021  -3.787  -49.875 1.000 22.116  0 36   ASP A OD1   1 ? 
ATOM   256  O OD2   . ASP A 1 37  ? -5.150  -4.399  -50.081 1.000 22.865  0 36   ASP A OD2   1 ? 
ATOM   257  N N     . TRP A 1 38  ? -0.304  -4.946  -49.211 1.000 20.639  0 37   TRP A N     1 ? 
ATOM   258  C CA    . TRP A 1 38  ? 0.804   -4.686  -50.096 1.000 21.039  0 37   TRP A CA    1 ? 
ATOM   259  C C     . TRP A 1 38  ? 0.351   -4.477  -51.535 1.000 23.277  0 37   TRP A C     1 ? 
ATOM   260  O O     . TRP A 1 38  ? 1.166   -4.628  -52.425 1.000 24.925  0 37   TRP A O     1 ? 
ATOM   261  C CB    . TRP A 1 38  ? 1.871   -5.789  -49.989 1.000 22.858  0 37   TRP A CB    1 ? 
ATOM   262  C CG    . TRP A 1 38  ? 2.810   -5.567  -48.840 1.000 24.505  0 37   TRP A CG    1 ? 
ATOM   263  C CD1   . TRP A 1 38  ? 2.491   -5.537  -47.509 1.000 24.550  0 37   TRP A CD1   1 ? 
ATOM   264  C CD2   . TRP A 1 38  ? 4.241   -5.411  -48.917 1.000 26.139  0 37   TRP A CD2   1 ? 
ATOM   265  N NE1   . TRP A 1 38  ? 3.619   -5.329  -46.763 1.000 29.367  0 37   TRP A NE1   1 ? 
ATOM   266  C CE2   . TRP A 1 38  ? 4.707   -5.269  -47.599 1.000 28.313  0 37   TRP A CE2   1 ? 
ATOM   267  C CE3   . TRP A 1 38  ? 5.163   -5.425  -49.968 1.000 30.959  0 37   TRP A CE3   1 ? 
ATOM   268  C CZ2   . TRP A 1 38  ? 6.061   -5.115  -47.299 1.000 32.306  0 37   TRP A CZ2   1 ? 
ATOM   269  C CZ3   . TRP A 1 38  ? 6.504   -5.300  -49.667 1.000 31.627  0 37   TRP A CZ3   1 ? 
ATOM   270  C CH2   . TRP A 1 38  ? 6.939   -5.134  -48.355 1.000 31.418  0 37   TRP A CH2   1 ? 
ATOM   271  N N     . LYS A 1 39  ? -0.904  -4.063  -51.748 1.000 20.704  0 38   LYS A N     1 ? 
ATOM   272  C CA    . LYS A 1 39  ? -1.448  -3.832  -53.074 1.000 25.475  0 38   LYS A CA    1 ? 
ATOM   273  C C     . LYS A 1 39  ? -2.186  -2.482  -53.140 1.000 24.118  0 38   LYS A C     1 ? 
ATOM   274  O O     . LYS A 1 39  ? -2.076  -1.774  -54.138 1.000 24.866  0 38   LYS A O     1 ? 
ATOM   275  C CB    . LYS A 1 39  ? -2.428  -4.955  -53.446 1.000 31.383  0 38   LYS A CB    1 ? 
ATOM   276  C CG    . LYS A 1 39  ? -3.101  -4.794  -54.810 1.000 41.464  0 38   LYS A CG    1 ? 
ATOM   277  C CD    . LYS A 1 39  ? -4.440  -5.517  -54.937 1.000 53.938  0 38   LYS A CD    1 ? 
ATOM   278  C CE    . LYS A 1 39  ? -5.232  -5.094  -56.141 1.000 59.496  0 38   LYS A CE    1 ? 
ATOM   279  N NZ    . LYS A 1 39  ? -4.535  -5.449  -57.379 1.000 62.682  0 38   LYS A NZ    1 ? 
ATOM   280  N N     . THR A 1 40  ? -3.004  -2.176  -52.127 1.000 19.077  0 39   THR A N     1 ? 
ATOM   281  C CA    . THR A 1 40  ? -3.866  -0.997  -52.140 1.000 20.484  0 39   THR A CA    1 ? 
ATOM   282  C C     . THR A 1 40  ? -2.993  0.252   -52.081 1.000 20.122  0 39   THR A C     1 ? 
ATOM   283  O O     . THR A 1 40  ? -2.178  0.381   -51.184 1.000 21.500  0 39   THR A O     1 ? 
ATOM   284  C CB    . THR A 1 40  ? -4.834  -1.024  -50.952 1.000 20.596  0 39   THR A CB    1 ? 
ATOM   285  O OG1   . THR A 1 40  ? -5.812  -2.031  -51.189 1.000 20.811  0 39   THR A OG1   1 ? 
ATOM   286  C CG2   . THR A 1 40  ? -5.533  0.314   -50.764 1.000 18.116  0 39   THR A CG2   1 ? 
ATOM   287  N N     . THR A 1 41  ? -3.172  1.204   -53.003 1.000 20.635  0 40   THR A N     1 ? 
ATOM   288  C CA    . THR A 1 41  ? -2.300  2.369   -53.038 1.000 19.140  0 40   THR A CA    1 ? 
ATOM   289  C C     . THR A 1 41  ? -2.944  3.489   -52.236 1.000 18.486  0 40   THR A C     1 ? 
ATOM   290  O O     . THR A 1 41  ? -4.128  3.815   -52.360 1.000 18.786  0 40   THR A O     1 ? 
ATOM   291  C CB    . THR A 1 41  ? -1.919  2.791   -54.461 1.000 19.854  0 40   THR A CB    1 ? 
ATOM   292  O OG1   . THR A 1 41  ? -3.151  3.012   -55.132 1.000 20.908  0 40   THR A OG1   1 ? 
ATOM   293  C CG2   . THR A 1 41  ? -1.124  1.691   -55.157 1.000 21.503  0 40   THR A CG2   1 ? 
ATOM   294  N N     . VAL A 1 42  ? -2.087  4.097   -51.416 1.000 19.656  0 41   VAL A N     1 ? 
ATOM   295  C CA    . VAL A 1 42  ? -2.453  5.185   -50.541 1.000 18.460  0 41   VAL A CA    1 ? 
ATOM   296  C C     . VAL A 1 42  ? -1.397  6.285   -50.651 1.000 19.094  0 41   VAL A C     1 ? 
ATOM   297  O O     . VAL A 1 42  ? -0.199  6.026   -50.611 1.000 19.807  0 41   VAL A O     1 ? 
ATOM   298  C CB    . VAL A 1 42  ? -2.559  4.692   -49.078 1.000 18.954  0 41   VAL A CB    1 ? 
ATOM   299  C CG1   . VAL A 1 42  ? -2.896  5.841   -48.155 1.000 20.533  0 41   VAL A CG1   1 ? 
ATOM   300  C CG2   . VAL A 1 42  ? -3.580  3.601   -48.907 1.000 19.089  0 41   VAL A CG2   1 ? 
ATOM   301  N N     . LEU A 1 43  ? -1.899  7.505   -50.839 1.000 18.932  0 42   LEU A N     1 ? 
ATOM   302  C CA    . LEU A 1 43  ? -1.154  8.725   -50.646 1.000 19.548  0 42   LEU A CA    1 ? 
ATOM   303  C C     . LEU A 1 43  ? -1.661  9.371   -49.364 1.000 18.092  0 42   LEU A C     1 ? 
ATOM   304  O O     . LEU A 1 43  ? -2.867  9.590   -49.221 1.000 19.210  0 42   LEU A O     1 ? 
ATOM   305  C CB    . LEU A 1 43  ? -1.355  9.696   -51.805 1.000 20.215  0 42   LEU A CB    1 ? 
ATOM   306  C CG    . LEU A 1 43  ? -0.535  10.983  -51.686 1.000 19.752  0 42   LEU A CG    1 ? 
ATOM   307  C CD1   . LEU A 1 43  ? 0.942   10.717  -51.752 1.000 19.606  0 42   LEU A CD1   1 ? 
ATOM   308  C CD2   . LEU A 1 43  ? -0.958  11.955  -52.727 1.000 22.369  0 42   LEU A CD2   1 ? 
ATOM   309  N N     . LEU A 1 44  ? -0.718  9.606   -48.459 1.000 16.212  0 43   LEU A N     1 ? 
ATOM   310  C CA    . LEU A 1 44  ? -0.941  10.290  -47.194 1.000 16.301  0 43   LEU A CA    1 ? 
ATOM   311  C C     . LEU A 1 44  ? -0.321  11.677  -47.319 1.000 17.598  0 43   LEU A C     1 ? 
ATOM   312  O O     . LEU A 1 44  ? 0.873   11.787  -47.576 1.000 18.519  0 43   LEU A O     1 ? 
ATOM   313  C CB    . LEU A 1 44  ? -0.297  9.491   -46.069 1.000 16.078  0 43   LEU A CB    1 ? 
ATOM   314  C CG    . LEU A 1 44  ? -0.453  10.094  -44.663 1.000 16.253  0 43   LEU A CG    1 ? 
ATOM   315  C CD1   . LEU A 1 44  ? -1.886  10.219  -44.198 1.000 18.020  0 43   LEU A CD1   1 ? 
ATOM   316  C CD2   . LEU A 1 44  ? 0.336   9.203   -43.773 1.000 17.318  0 43   LEU A CD2   1 ? 
ATOM   317  N N     . ILE A 1 45  ? -1.154  12.706  -47.155 1.000 17.511  0 44   ILE A N     1 ? 
ATOM   318  C CA    . ILE A 1 45  ? -0.751  14.096  -47.272 1.000 20.508  0 44   ILE A CA    1 ? 
ATOM   319  C C     . ILE A 1 45  ? -0.815  14.760  -45.897 1.000 18.335  0 44   ILE A C     1 ? 
ATOM   320  O O     . ILE A 1 45  ? -1.859  14.758  -45.238 1.000 20.686  0 44   ILE A O     1 ? 
ATOM   321  C CB    . ILE A 1 45  ? -1.606  14.878  -48.274 1.000 19.854  0 44   ILE A CB    1 ? 
ATOM   322  C CG1   . ILE A 1 45  ? -1.730  14.141  -49.595 1.000 22.113  0 44   ILE A CG1   1 ? 
ATOM   323  C CG2   . ILE A 1 45  ? -1.051  16.296  -48.471 1.000 23.699  0 44   ILE A CG2   1 ? 
ATOM   324  C CD1   . ILE A 1 45  ? -2.613  14.861  -50.599 1.000 23.211  0 44   ILE A CD1   1 ? 
ATOM   325  N N     . GLU A 1 46  ? 0.314   15.350  -45.515 1.000 16.947  0 45   GLU A N     1 ? 
ATOM   326  C CA    . GLU A 1 46  ? 0.467   15.985  -44.204 1.000 17.831  0 45   GLU A CA    1 ? 
ATOM   327  C C     . GLU A 1 46  ? 1.031   17.397  -44.357 1.000 17.802  0 45   GLU A C     1 ? 
ATOM   328  O O     . GLU A 1 46  ? 2.070   17.580  -45.013 1.000 18.099  0 45   GLU A O     1 ? 
ATOM   329  C CB    . GLU A 1 46  ? 1.447   15.154  -43.371 1.000 19.789  0 45   GLU A CB    1 ? 
ATOM   330  C CG    . GLU A 1 46  ? 1.881   15.784  -42.045 1.000 21.346  0 45   GLU A CG    1 ? 
ATOM   331  C CD    . GLU A 1 46  ? 0.784   16.334  -41.123 1.000 22.344  0 45   GLU A CD    1 ? 
ATOM   332  O OE1   . GLU A 1 46  ? -0.234  15.621  -40.950 1.000 21.529  0 45   GLU A OE1   1 ? 
ATOM   333  O OE2   . GLU A 1 46  ? 0.967   17.431  -40.519 1.000 22.725  0 45   GLU A OE2   1 ? 
ATOM   334  N N     . ALA A 1 47  ? 0.413   18.342  -43.614 1.000 18.475  0 46   ALA A N     1 ? 
ATOM   335  C CA    . ALA A 1 47  ? 0.755   19.752  -43.676 1.000 19.227  0 46   ALA A CA    1 ? 
ATOM   336  C C     . ALA A 1 47  ? 2.129   20.012  -43.067 1.000 20.553  0 46   ALA A C     1 ? 
ATOM   337  O O     . ALA A 1 47  ? 2.841   20.910  -43.507 1.000 20.225  0 46   ALA A O     1 ? 
ATOM   338  C CB    . ALA A 1 47  ? -0.315  20.555  -42.979 1.000 19.893  0 46   ALA A CB    1 ? 
ATOM   339  N N     . GLY A 1 48  ? 2.485   19.243  -42.036 1.000 20.185  0 47   GLY A N     1 ? 
ATOM   340  C CA    . GLY A 1 48  ? 3.628   19.543  -41.184 1.000 22.648  0 47   GLY A CA    1 ? 
ATOM   341  C C     . GLY A 1 48  ? 4.924   18.846  -41.606 1.000 20.006  0 47   GLY A C     1 ? 
ATOM   342  O O     . GLY A 1 48  ? 5.025   18.251  -42.683 1.000 20.341  0 47   GLY A O     1 ? 
ATOM   343  N N     . ILE A 1 49  ? 5.900   18.925  -40.711 1.000 18.847  0 48   ILE A N     1 ? 
ATOM   344  C CA    . ILE A 1 49  ? 7.258   18.462  -40.939 1.000 19.690  0 48   ILE A CA    1 ? 
ATOM   345  C C     . ILE A 1 49  ? 7.410   17.019  -40.460 1.000 20.149  0 48   ILE A C     1 ? 
ATOM   346  O O     . ILE A 1 49  ? 6.567   16.486  -39.734 1.000 17.918  0 48   ILE A O     1 ? 
ATOM   347  C CB    . ILE A 1 49  ? 8.266   19.398  -40.248 1.000 22.021  0 48   ILE A CB    1 ? 
ATOM   348  C CG1   . ILE A 1 49  ? 8.076   19.420  -38.717 1.000 21.310  0 48   ILE A CG1   1 ? 
ATOM   349  C CG2   . ILE A 1 49  ? 8.192   20.795  -40.853 1.000 22.380  0 48   ILE A CG2   1 ? 
ATOM   350  C CD1   . ILE A 1 49  ? 9.203   20.131  -37.993 1.000 24.285  0 48   ILE A CD1   1 ? 
ATOM   351  N N     . SER A 1 50  ? 8.544   16.434  -40.827 1.000 20.070  0 49   SER A N     1 ? 
ATOM   352  C CA    . SER A 1 50  ? 8.957   15.133  -40.363 1.000 23.029  0 49   SER A CA    1 ? 
ATOM   353  C C     . SER A 1 50  ? 9.202   15.197  -38.857 1.000 20.264  0 49   SER A C     1 ? 
ATOM   354  O O     . SER A 1 50  ? 9.692   16.211  -38.381 1.000 19.424  0 49   SER A O     1 ? 
ATOM   355  C CB    . SER A 1 50  ? 10.219  14.725  -41.076 1.000 22.374  0 49   SER A CB    1 ? 
ATOM   356  O OG    . SER A 1 50  ? 10.676  13.515  -40.501 1.000 21.852  0 49   SER A OG    1 ? 
ATOM   357  N N     . HIS A 1 51  ? 8.896   14.110  -38.147 1.000 19.616  0 50   HIS A N     1 ? 
ATOM   358  C CA    . HIS A 1 51  ? 9.221   13.989  -36.725 1.000 20.426  0 50   HIS A CA    1 ? 
ATOM   359  C C     . HIS A 1 51  ? 10.679  13.601  -36.484 1.000 23.424  0 50   HIS A C     1 ? 
ATOM   360  O O     . HIS A 1 51  ? 11.150  13.574  -35.331 1.000 22.338  0 50   HIS A O     1 ? 
ATOM   361  C CB    . HIS A 1 51  ? 8.314   12.925  -36.107 1.000 21.047  0 50   HIS A CB    1 ? 
ATOM   362  C CG    . HIS A 1 51  ? 8.495   11.595  -36.694 1.000 21.851  0 50   HIS A CG    1 ? 
ATOM   363  N ND1   . HIS A 1 51  ? 8.213   11.376  -38.027 1.000 24.026  0 50   HIS A ND1   1 ? 
ATOM   364  C CD2   . HIS A 1 51  ? 9.095   10.474  -36.235 1.000 23.514  0 50   HIS A CD2   1 ? 
ATOM   365  C CE1   . HIS A 1 51  ? 8.537   10.123  -38.324 1.000 24.474  0 50   HIS A CE1   1 ? 
ATOM   366  N NE2   . HIS A 1 51  ? 9.080   9.554   -37.264 1.000 25.098  0 50   HIS A NE2   1 ? 
ATOM   367  N N     . GLU A 1 52  ? 11.394  13.254  -37.557 1.000 23.833  0 51   GLU A N     1 ? 
ATOM   368  C CA    . GLU A 1 52  ? 12.678  12.578  -37.417 1.000 26.688  0 51   GLU A CA    1 ? 
ATOM   369  C C     . GLU A 1 52  ? 13.704  13.527  -36.825 1.000 27.512  0 51   GLU A C     1 ? 
ATOM   370  O O     . GLU A 1 52  ? 13.794  14.668  -37.240 1.000 25.188  0 51   GLU A O     1 ? 
ATOM   371  C CB    . GLU A 1 52  ? 13.262  12.074  -38.738 1.000 34.029  0 51   GLU A CB    1 ? 
ATOM   372  C CG    . GLU A 1 52  ? 12.467  10.924  -39.338 1.000 36.831  0 51   GLU A CG    1 ? 
ATOM   373  C CD    . GLU A 1 52  ? 12.590  9.600   -38.593 1.000 48.282  0 51   GLU A CD    1 ? 
ATOM   374  O OE1   . GLU A 1 52  ? 12.509  8.553   -39.278 1.000 56.808  0 51   GLU A OE1   1 ? 
ATOM   375  O OE2   . GLU A 1 52  ? 12.774  9.595   -37.347 1.000 51.322  0 51   GLU A OE2   1 ? 
ATOM   376  N N     . GLY A 1 53  ? 14.433  13.037  -35.816 1.000 27.908  0 52   GLY A N     1 ? 
ATOM   377  C CA    . GLY A 1 53  ? 15.546  13.772  -35.258 1.000 29.463  0 52   GLY A CA    1 ? 
ATOM   378  C C     . GLY A 1 53  ? 15.120  14.862  -34.273 1.000 28.301  0 52   GLY A C     1 ? 
ATOM   379  O O     . GLY A 1 53  ? 15.978  15.608  -33.823 1.000 30.847  0 52   GLY A O     1 ? 
ATOM   380  N N     . ILE A 1 54  ? 13.826  14.965  -33.914 1.000 22.252  0 53   ILE A N     1 ? 
ATOM   381  C CA    . ILE A 1 54  ? 13.385  16.036  -33.050 1.000 20.139  0 53   ILE A CA    1 ? 
ATOM   382  C C     . ILE A 1 54  ? 13.333  15.491  -31.627 1.000 20.983  0 53   ILE A C     1 ? 
ATOM   383  O O     . ILE A 1 54  ? 12.472  14.660  -31.315 1.000 21.345  0 53   ILE A O     1 ? 
ATOM   384  C CB    . ILE A 1 54  ? 12.020  16.605  -33.502 1.000 21.544  0 53   ILE A CB    1 ? 
ATOM   385  C CG1   . ILE A 1 54  ? 12.031  17.056  -34.952 1.000 24.537  0 53   ILE A CG1   1 ? 
ATOM   386  C CG2   . ILE A 1 54  ? 11.562  17.735  -32.599 1.000 21.512  0 53   ILE A CG2   1 ? 
ATOM   387  C CD1   . ILE A 1 54  ? 10.735  17.685  -35.413 1.000 26.503  0 53   ILE A CD1   1 ? 
ATOM   388  N N     . ASP A 1 55  ? 14.226  15.963  -30.753 1.000 20.324  0 54   ASP A N     1 ? 
ATOM   389  C CA    . ASP A 1 55  ? 14.271  15.419  -29.391 1.000 22.005  0 54   ASP A CA    1 ? 
ATOM   390  C C     . ASP A 1 55  ? 12.979  15.721  -28.625 1.000 20.946  0 54   ASP A C     1 ? 
ATOM   391  O O     . ASP A 1 55  ? 12.524  14.943  -27.778 1.000 19.649  0 54   ASP A O     1 ? 
ATOM   392  C CB    . ASP A 1 55  ? 15.420  16.014  -28.612 1.000 22.035  0 54   ASP A CB    1 ? 
ATOM   393  C CG    . ASP A 1 55  ? 16.797  15.598  -29.103 1.000 26.832  0 54   ASP A CG    1 ? 
ATOM   394  O OD1   . ASP A 1 55  ? 16.883  14.586  -29.871 1.000 29.053  0 54   ASP A OD1   1 ? 
ATOM   395  O OD2   . ASP A 1 55  ? 17.757  16.313  -28.730 1.000 28.263  0 54   ASP A OD2   1 ? 
ATOM   396  N N     . SER A 1 56  ? 12.391  16.890  -28.881 1.000 19.808  0 55   SER A N     1 ? 
ATOM   397  C CA    . SER A 1 56  ? 11.233  17.297  -28.103 1.000 20.633  0 55   SER A CA    1 ? 
ATOM   398  C C     . SER A 1 56  ? 9.993   16.484  -28.496 1.000 18.680  0 55   SER A C     1 ? 
ATOM   399  O O     . SER A 1 56  ? 8.946   16.662  -27.879 1.000 18.447  0 55   SER A O     1 ? 
ATOM   400  C CB    . SER A 1 56  ? 10.974  18.792  -28.174 1.000 20.794  0 55   SER A CB    1 ? 
ATOM   401  O OG    . SER A 1 56  ? 10.609  19.163  -29.495 1.000 21.725  0 55   SER A OG    1 ? 
ATOM   402  N N     . VAL A 1 57  ? 10.065  15.673  -29.561 1.000 17.277  0 56   VAL A N     1 ? 
ATOM   403  C CA    . VAL A 1 57  ? 9.032   14.693  -29.863 1.000 17.417  0 56   VAL A CA    1 ? 
ATOM   404  C C     . VAL A 1 57  ? 9.401   13.316  -29.261 1.000 18.564  0 56   VAL A C     1 ? 
ATOM   405  O O     . VAL A 1 57  ? 8.570   12.673  -28.635 1.000 18.840  0 56   VAL A O     1 ? 
ATOM   406  C CB    . VAL A 1 57  ? 8.769   14.619  -31.372 1.000 18.302  0 56   VAL A CB    1 ? 
ATOM   407  C CG1   . VAL A 1 57  ? 7.918   13.403  -31.775 1.000 20.757  0 56   VAL A CG1   1 ? 
ATOM   408  C CG2   . VAL A 1 57  ? 8.116   15.897  -31.864 1.000 20.036  0 56   VAL A CG2   1 ? 
ATOM   409  N N     . ALA A 1 58  ? 10.659  12.877  -29.386 1.000 16.961  0 57   ALA A N     1 ? 
ATOM   410  C CA    . ALA A 1 58  ? 11.038  11.504  -29.036 1.000 16.485  0 57   ALA A CA    1 ? 
ATOM   411  C C     . ALA A 1 58  ? 11.095  11.329  -27.518 1.000 16.034  0 57   ALA A C     1 ? 
ATOM   412  O O     . ALA A 1 58  ? 10.775  10.268  -26.979 1.000 17.555  0 57   ALA A O     1 ? 
ATOM   413  C CB    . ALA A 1 58  ? 12.392  11.181  -29.646 1.000 18.816  0 57   ALA A CB    1 ? 
ATOM   414  N N     . VAL A 1 59  ? 11.488  12.402  -26.833 1.000 17.646  0 58   VAL A N     1 ? 
ATOM   415  C CA    . VAL A 1 59  ? 11.817  12.340  -25.428 1.000 17.879  0 58   VAL A CA    1 ? 
ATOM   416  C C     . VAL A 1 59  ? 10.619  12.797  -24.608 1.000 18.364  0 58   VAL A C     1 ? 
ATOM   417  O O     . VAL A 1 59  ? 10.248  13.967  -24.658 1.000 17.293  0 58   VAL A O     1 ? 
ATOM   418  C CB    . VAL A 1 59  ? 13.056  13.179  -25.063 1.000 17.127  0 58   VAL A CB    1 ? 
ATOM   419  C CG1   . VAL A 1 59  ? 13.397  12.968  -23.591 1.000 15.677  0 58   VAL A CG1   1 ? 
ATOM   420  C CG2   . VAL A 1 59  ? 14.259  12.867  -25.938 1.000 19.008  0 58   VAL A CG2   1 ? 
ATOM   421  N N     . PRO A 1 60  ? 9.998   11.891  -23.812 1.000 17.047  0 59   PRO A N     1 ? 
ATOM   422  C CA    . PRO A 1 60  ? 8.783   12.224  -23.078 1.000 17.751  0 59   PRO A CA    1 ? 
ATOM   423  C C     . PRO A 1 60  ? 8.960   13.473  -22.237 1.000 18.150  0 59   PRO A C     1 ? 
ATOM   424  O O     . PRO A 1 60  ? 8.090   14.344  -22.230 1.000 18.113  0 59   PRO A O     1 ? 
ATOM   425  C CB    . PRO A 1 60  ? 8.512   10.973  -22.242 1.000 16.438  0 59   PRO A CB    1 ? 
ATOM   426  C CG    . PRO A 1 60  ? 9.053   9.850   -23.091 1.000 16.179  0 59   PRO A CG    1 ? 
ATOM   427  C CD    . PRO A 1 60  ? 10.328  10.462  -23.700 1.000 16.753  0 59   PRO A CD    1 ? 
ATOM   428  N N     . GLY A 1 61  ? 10.124  13.562  -21.590 1.000 17.379  0 60   GLY A N     1 ? 
ATOM   429  C CA    . GLY A 1 61  ? 10.374  14.613  -20.617 1.000 19.124  0 60   GLY A CA    1 ? 
ATOM   430  C C     . GLY A 1 61  ? 10.510  16.008  -21.235 1.000 17.642  0 60   GLY A C     1 ? 
ATOM   431  O O     . GLY A 1 61  ? 10.590  17.001  -20.508 1.000 17.892  0 60   GLY A O     1 ? 
ATOM   432  N N     . LEU A 1 62  ? 10.632  16.092  -22.560 1.000 19.241  0 61   LEU A N     1 ? 
ATOM   433  C CA    . LEU A 1 62  ? 10.852  17.379  -23.200 1.000 19.390  0 61   LEU A CA    1 ? 
ATOM   434  C C     . LEU A 1 62  ? 9.539   17.939  -23.752 1.000 21.363  0 61   LEU A C     1 ? 
ATOM   435  O O     . LEU A 1 62  ? 9.572   18.967  -24.419 1.000 20.172  0 61   LEU A O     1 ? 
ATOM   436  C CB    . LEU A 1 62  ? 11.870  17.249  -24.326 1.000 19.278  0 61   LEU A CB    1 ? 
ATOM   437  C CG    . LEU A 1 62  ? 13.316  16.955  -23.923 1.000 21.479  0 61   LEU A CG    1 ? 
ATOM   438  C CD1   . LEU A 1 62  ? 14.154  16.879  -25.170 1.000 21.418  0 61   LEU A CD1   1 ? 
ATOM   439  C CD2   . LEU A 1 62  ? 13.860  18.035  -22.975 1.000 22.594  0 61   LEU A CD2   1 ? 
ATOM   440  N N     . VAL A 1 63  ? 8.416   17.266  -23.479 1.000 19.072  0 62   VAL A N     1 ? 
ATOM   441  C CA    . VAL A 1 63  ? 7.149   17.585  -24.115 1.000 18.115  0 62   VAL A CA    1 ? 
ATOM   442  C C     . VAL A 1 63  ? 6.780   19.062  -23.922 1.000 19.436  0 62   VAL A C     1 ? 
ATOM   443  O O     . VAL A 1 63  ? 6.268   19.687  -24.855 1.000 20.440  0 62   VAL A O     1 ? 
ATOM   444  C CB    . VAL A 1 63  ? 6.050   16.625  -23.631 1.000 16.406  0 62   VAL A CB    1 ? 
ATOM   445  C CG1   . VAL A 1 63  ? 5.745   16.758  -22.145 1.000 18.147  0 62   VAL A CG1   1 ? 
ATOM   446  C CG2   . VAL A 1 63  ? 4.768   16.775  -24.430 1.000 18.631  0 62   VAL A CG2   1 ? 
ATOM   447  N N     . LEU A 1 64  ? 7.030   19.665  -22.729 1.000 19.208  0 63   LEU A N     1 ? 
ATOM   448  C CA    . LEU A 1 64  ? 6.589   21.039  -22.518 1.000 21.320  0 63   LEU A CA    1 ? 
ATOM   449  C C     . LEU A 1 64  ? 7.362   22.023  -23.404 1.000 21.687  0 63   LEU A C     1 ? 
ATOM   450  O O     . LEU A 1 64  ? 6.921   23.156  -23.622 1.000 22.448  0 63   LEU A O     1 ? 
ATOM   451  C CB    . LEU A 1 64  ? 6.690   21.436  -21.049 1.000 22.618  0 63   LEU A CB    1 ? 
ATOM   452  C CG    . LEU A 1 64  ? 5.792   20.621  -20.111 1.000 24.134  0 63   LEU A CG    1 ? 
ATOM   453  C CD1   . LEU A 1 64  ? 6.070   20.957  -18.655 1.000 26.238  0 63   LEU A CD1   1 ? 
ATOM   454  C CD2   . LEU A 1 64  ? 4.330   20.861  -20.472 1.000 26.344  0 63   LEU A CD2   1 ? 
ATOM   455  N N     . ASP A 1 65  ? 8.517   21.613  -23.926 1.000 22.990  0 64   ASP A N     1 ? 
ATOM   456  C CA    . ASP A 1 65  ? 9.307   22.498  -24.768 1.000 23.769  0 64   ASP A CA    1 ? 
ATOM   457  C C     . ASP A 1 65  ? 8.593   22.864  -26.070 1.000 23.879  0 64   ASP A C     1 ? 
ATOM   458  O O     . ASP A 1 65  ? 9.010   23.807  -26.732 1.000 24.245  0 64   ASP A O     1 ? 
ATOM   459  C CB    . ASP A 1 65  ? 10.662  21.898  -25.102 1.000 28.127  0 64   ASP A CB    1 ? 
ATOM   460  C CG    . ASP A 1 65  ? 11.714  21.940  -24.001 1.000 32.141  0 64   ASP A CG    1 ? 
ATOM   461  O OD1   . ASP A 1 65  ? 11.478  22.610  -22.987 1.000 33.899  0 64   ASP A OD1   1 ? 
ATOM   462  O OD2   . ASP A 1 65  ? 12.771  21.293  -24.174 1.000 33.940  0 64   ASP A OD2   1 ? 
ATOM   463  N N     . ASN A 1 66  ? 7.547   22.121  -26.468 1.000 21.812  0 65   ASN A N     1 ? 
ATOM   464  C CA    . ASN A 1 66  ? 6.897   22.391  -27.745 1.000 21.306  0 65   ASN A CA    1 ? 
ATOM   465  C C     . ASN A 1 66  ? 5.809   23.444  -27.594 1.000 22.135  0 65   ASN A C     1 ? 
ATOM   466  O O     . ASN A 1 66  ? 5.225   23.817  -28.615 1.000 23.037  0 65   ASN A O     1 ? 
ATOM   467  C CB    . ASN A 1 66  ? 6.249   21.161  -28.355 1.000 20.429  0 65   ASN A CB    1 ? 
ATOM   468  C CG    . ASN A 1 66  ? 7.273   20.091  -28.651 1.000 23.594  0 65   ASN A CG    1 ? 
ATOM   469  O OD1   . ASN A 1 66  ? 8.347   20.369  -29.211 1.000 23.913  0 65   ASN A OD1   1 ? 
ATOM   470  N ND2   . ASN A 1 66  ? 6.961   18.873  -28.248 1.000 21.407  0 65   ASN A ND2   1 ? 
ATOM   471  N N     . LEU A 1 67  ? 5.568   23.877  -26.342 1.000 20.931  0 66   LEU A N     1 ? 
ATOM   472  C CA    . LEU A 1 67  ? 4.470   24.768  -26.022 1.000 26.018  0 66   LEU A CA    1 ? 
ATOM   473  C C     . LEU A 1 67  ? 5.057   26.064  -25.472 1.000 27.128  0 66   LEU A C     1 ? 
ATOM   474  O O     . LEU A 1 67  ? 6.042   26.012  -24.756 1.000 24.918  0 66   LEU A O     1 ? 
ATOM   475  C CB    . LEU A 1 67  ? 3.514   24.149  -25.007 1.000 25.922  0 66   LEU A CB    1 ? 
ATOM   476  C CG    . LEU A 1 67  ? 2.791   22.886  -25.481 1.000 26.459  0 66   LEU A CG    1 ? 
ATOM   477  C CD1   . LEU A 1 67  ? 2.356   22.045  -24.308 1.000 29.320  0 66   LEU A CD1   1 ? 
ATOM   478  C CD2   . LEU A 1 67  ? 1.592   23.275  -26.346 1.000 30.122  0 66   LEU A CD2   1 ? 
ATOM   479  N N     . PRO A 1 68  ? 4.465   27.248  -25.763 1.000 31.035  0 67   PRO A N     1 ? 
ATOM   480  C CA    . PRO A 1 68  ? 3.241   27.351  -26.568 1.000 31.513  0 67   PRO A CA    1 ? 
ATOM   481  C C     . PRO A 1 68  ? 3.450   27.400  -28.075 1.000 33.459  0 67   PRO A C     1 ? 
ATOM   482  O O     . PRO A 1 68  ? 2.494   27.347  -28.841 1.000 35.077  0 67   PRO A O     1 ? 
ATOM   483  C CB    . PRO A 1 68  ? 2.630   28.672  -26.052 1.000 39.719  0 67   PRO A CB    1 ? 
ATOM   484  C CG    . PRO A 1 68  ? 3.804   29.497  -25.589 1.000 35.463  0 67   PRO A CG    1 ? 
ATOM   485  C CD    . PRO A 1 68  ? 4.935   28.544  -25.252 1.000 34.939  0 67   PRO A CD    1 ? 
ATOM   486  N N     . PHE A 1 69  ? 4.710   27.521  -28.501 1.000 29.306  0 68   PHE A N     1 ? 
ATOM   487  C CA    . PHE A 1 69  ? 5.009   27.838  -29.883 1.000 29.484  0 68   PHE A CA    1 ? 
ATOM   488  C C     . PHE A 1 69  ? 6.244   27.043  -30.270 1.000 27.886  0 68   PHE A C     1 ? 
ATOM   489  O O     . PHE A 1 69  ? 7.246   27.102  -29.583 1.000 26.899  0 68   PHE A O     1 ? 
ATOM   490  C CB    . PHE A 1 69  ? 5.208   29.365  -29.949 1.000 31.347  0 68   PHE A CB    1 ? 
ATOM   491  C CG    . PHE A 1 69  ? 5.578   29.941  -31.314 1.000 30.009  0 68   PHE A CG    1 ? 
ATOM   492  C CD1   . PHE A 1 69  ? 6.902   29.969  -31.744 1.000 30.067  0 68   PHE A CD1   1 ? 
ATOM   493  C CD2   . PHE A 1 69  ? 4.601   30.465  -32.147 1.000 28.976  0 68   PHE A CD2   1 ? 
ATOM   494  C CE1   . PHE A 1 69  ? 7.233   30.469  -32.999 1.000 30.072  0 68   PHE A CE1   1 ? 
ATOM   495  C CE2   . PHE A 1 69  ? 4.942   30.976  -33.390 1.000 27.586  0 68   PHE A CE2   1 ? 
ATOM   496  C CZ    . PHE A 1 69  ? 6.246   30.990  -33.808 1.000 28.526  0 68   PHE A CZ    1 ? 
ATOM   497  N N     . SER A 1 70  ? 6.179   26.283  -31.352 1.000 23.800  0 69   SER A N     1 ? 
ATOM   498  C CA    . SER A 1 70  ? 7.339   25.565  -31.815 1.000 25.392  0 69   SER A CA    1 ? 
ATOM   499  C C     . SER A 1 70  ? 7.116   25.126  -33.247 1.000 23.375  0 69   SER A C     1 ? 
ATOM   500  O O     . SER A 1 70  ? 6.002   25.139  -33.709 1.000 22.894  0 69   SER A O     1 ? 
ATOM   501  C CB    . SER A 1 70  ? 7.617   24.371  -30.953 1.000 26.203  0 69   SER A CB    1 ? 
ATOM   502  O OG    . SER A 1 70  ? 6.474   23.537  -31.004 1.000 26.414  0 69   SER A OG    1 ? 
ATOM   503  N N     . PRO A 1 71  ? 8.148   24.648  -33.949 1.000 28.609  0 70   PRO A N     1 ? 
ATOM   504  C CA    . PRO A 1 71  ? 7.960   24.176  -35.322 1.000 28.435  0 70   PRO A CA    1 ? 
ATOM   505  C C     . PRO A 1 71  ? 6.985   23.002  -35.467 1.000 27.422  0 70   PRO A C     1 ? 
ATOM   506  O O     . PRO A 1 71  ? 6.546   22.741  -36.569 1.000 28.752  0 70   PRO A O     1 ? 
ATOM   507  C CB    . PRO A 1 71  ? 9.359   23.773  -35.791 1.000 29.827  0 70   PRO A CB    1 ? 
ATOM   508  C CG    . PRO A 1 71  ? 10.320  24.363  -34.781 1.000 35.917  0 70   PRO A CG    1 ? 
ATOM   509  C CD    . PRO A 1 71  ? 9.543   24.541  -33.477 1.000 33.085  0 70   PRO A CD    1 ? 
ATOM   510  N N     . VAL A 1 72  ? 6.716   22.238  -34.397 1.000 21.771  0 71   VAL A N     1 ? 
ATOM   511  C CA    . VAL A 1 72  ? 5.924   21.018  -34.526 1.000 21.108  0 71   VAL A CA    1 ? 
ATOM   512  C C     . VAL A 1 72  ? 4.476   21.280  -34.144 1.000 22.326  0 71   VAL A C     1 ? 
ATOM   513  O O     . VAL A 1 72  ? 3.673   20.347  -34.099 1.000 23.719  0 71   VAL A O     1 ? 
ATOM   514  C CB    . VAL A 1 72  ? 6.461   19.833  -33.700 1.000 22.469  0 71   VAL A CB    1 ? 
ATOM   515  C CG1   . VAL A 1 72  ? 7.720   19.230  -34.303 1.000 22.792  0 71   VAL A CG1   1 ? 
ATOM   516  C CG2   . VAL A 1 72  ? 6.674   20.213  -32.225 1.000 22.478  0 71   VAL A CG2   1 ? 
ATOM   517  N N     . MET A 1 73  ? 4.144   22.530  -33.846 1.000 22.354  0 72   MET A N     1 ? 
ATOM   518  C CA    . MET A 1 73  ? 2.868   22.839  -33.237 1.000 25.859  0 72   MET A CA    1 ? 
ATOM   519  C C     . MET A 1 73  ? 2.170   23.904  -34.066 1.000 24.173  0 72   MET A C     1 ? 
ATOM   520  O O     . MET A 1 73  ? 2.806   24.825  -34.555 1.000 28.542  0 72   MET A O     1 ? 
ATOM   521  C CB    . MET A 1 73  ? 3.101   23.315  -31.799 1.000 26.187  0 72   MET A CB    1 ? 
ATOM   522  C CG    . MET A 1 73  ? 1.873   23.286  -30.971 1.000 31.808  0 72   MET A CG    1 ? 
ATOM   523  S SD    . MET A 1 73  ? 1.439   21.624  -30.409 1.000 27.195  0 72   MET A SD    1 ? 
ATOM   524  C CE    . MET A 1 73  ? 2.627   21.283  -29.105 1.000 27.283  0 72   MET A CE    1 ? 
ATOM   525  N N     . TRP A 1 74  ? 0.880   23.705  -34.313 1.000 21.572  0 73   TRP A N     1 ? 
ATOM   526  C CA    . TRP A 1 74  ? 0.017   24.748  -34.816 1.000 22.708  0 73   TRP A CA    1 ? 
ATOM   527  C C     . TRP A 1 74  ? -0.499  25.542  -33.613 1.000 25.255  0 73   TRP A C     1 ? 
ATOM   528  O O     . TRP A 1 74  ? -1.006  24.953  -32.663 1.000 25.178  0 73   TRP A O     1 ? 
ATOM   529  C CB    . TRP A 1 74  ? -1.123  24.102  -35.593 1.000 24.094  0 73   TRP A CB    1 ? 
ATOM   530  C CG    . TRP A 1 74  ? -2.096  25.039  -36.221 1.000 29.866  0 73   TRP A CG    1 ? 
ATOM   531  C CD1   . TRP A 1 74  ? -2.130  25.456  -37.529 1.000 34.975  0 73   TRP A CD1   1 ? 
ATOM   532  C CD2   . TRP A 1 74  ? -3.302  25.517  -35.594 1.000 27.998  0 73   TRP A CD2   1 ? 
ATOM   533  N NE1   . TRP A 1 74  ? -3.259  26.206  -37.740 1.000 38.486  0 73   TRP A NE1   1 ? 
ATOM   534  C CE2   . TRP A 1 74  ? -4.007  26.234  -36.590 1.000 34.223  0 73   TRP A CE2   1 ? 
ATOM   535  C CE3   . TRP A 1 74  ? -3.854  25.388  -34.307 1.000 26.372  0 73   TRP A CE3   1 ? 
ATOM   536  C CZ2   . TRP A 1 74  ? -5.226  26.838  -36.326 1.000 29.340  0 73   TRP A CZ2   1 ? 
ATOM   537  C CZ3   . TRP A 1 74  ? -5.085  25.966  -34.061 1.000 28.233  0 73   TRP A CZ3   1 ? 
ATOM   538  C CH2   . TRP A 1 74  ? -5.739  26.686  -35.059 1.000 28.591  0 73   TRP A CH2   1 ? 
ATOM   539  N N     . ASN A 1 75  ? -0.302  26.862  -33.621 1.000 23.785  0 74   ASN A N     1 ? 
ATOM   540  C CA    . ASN A 1 75  ? -0.688  27.693  -32.485 1.000 25.170  0 74   ASN A CA    1 ? 
ATOM   541  C C     . ASN A 1 75  ? -1.723  28.700  -32.968 1.000 26.134  0 74   ASN A C     1 ? 
ATOM   542  O O     . ASN A 1 75  ? -1.567  29.337  -33.996 1.000 22.615  0 74   ASN A O     1 ? 
ATOM   543  C CB    . ASN A 1 75  ? 0.473   28.393  -31.780 1.000 29.180  0 74   ASN A CB    1 ? 
ATOM   544  C CG    . ASN A 1 75  ? 1.172   29.387  -32.676 1.000 37.753  0 74   ASN A CG    1 ? 
ATOM   545  O OD1   . ASN A 1 75  ? 1.014   30.625  -32.555 1.000 38.516  0 74   ASN A OD1   1 ? 
ATOM   546  N ND2   . ASN A 1 75  ? 1.935   28.848  -33.612 1.000 31.710  0 74   ASN A ND2   1 ? 
ATOM   547  N N     . TYR A 1 76  ? -2.789  28.839  -32.215 1.000 26.776  0 75   TYR A N     1 ? 
ATOM   548  C CA    . TYR A 1 76  ? -3.732  29.889  -32.508 1.000 27.304  0 75   TYR A CA    1 ? 
ATOM   549  C C     . TYR A 1 76  ? -4.449  30.230  -31.212 1.000 28.595  0 75   TYR A C     1 ? 
ATOM   550  O O     . TYR A 1 76  ? -4.003  29.854  -30.125 1.000 30.280  0 75   TYR A O     1 ? 
ATOM   551  C CB    . TYR A 1 76  ? -4.653  29.533  -33.671 1.000 29.082  0 75   TYR A CB    1 ? 
ATOM   552  C CG    . TYR A 1 76  ? -5.366  30.756  -34.257 1.000 26.158  0 75   TYR A CG    1 ? 
ATOM   553  C CD1   . TYR A 1 76  ? -4.674  31.928  -34.550 1.000 30.177  0 75   TYR A CD1   1 ? 
ATOM   554  C CD2   . TYR A 1 76  ? -6.741  30.749  -34.454 1.000 32.404  0 75   TYR A CD2   1 ? 
ATOM   555  C CE1   . TYR A 1 76  ? -5.320  33.035  -35.066 1.000 34.792  0 75   TYR A CE1   1 ? 
ATOM   556  C CE2   . TYR A 1 76  ? -7.404  31.842  -34.986 1.000 35.408  0 75   TYR A CE2   1 ? 
ATOM   557  C CZ    . TYR A 1 76  ? -6.690  32.997  -35.271 1.000 42.266  0 75   TYR A CZ    1 ? 
ATOM   558  O OH    . TYR A 1 76  ? -7.347  34.070  -35.799 1.000 41.158  0 75   TYR A OH    1 ? 
ATOM   559  N N     . THR A 1 77  ? -5.470  31.070  -31.307 1.000 25.047  0 76   THR A N     1 ? 
ATOM   560  C CA    . THR A 1 77  ? -6.218  31.367  -30.104 1.000 29.319  0 76   THR A CA    1 ? 
ATOM   561  C C     . THR A 1 77  ? -7.686  31.309  -30.477 1.000 28.042  0 76   THR A C     1 ? 
ATOM   562  O O     . THR A 1 77  ? -8.026  31.389  -31.658 1.000 28.942  0 76   THR A O     1 ? 
ATOM   563  C CB    . THR A 1 77  ? -5.766  32.692  -29.487 1.000 34.651  0 76   THR A CB    1 ? 
ATOM   564  O OG1   . THR A 1 77  ? -6.675  33.732  -29.805 1.000 42.503  0 76   THR A OG1   1 ? 
ATOM   565  C CG2   . THR A 1 77  ? -4.374  33.092  -29.944 1.000 34.723  0 76   THR A CG2   1 ? 
ATOM   566  N N     . THR A 1 78  ? -8.511  31.160  -29.448 1.000 26.590  0 77   THR A N     1 ? 
ATOM   567  C CA    . THR A 1 78  ? -9.943  31.297  -29.556 1.000 25.307  0 77   THR A CA    1 ? 
ATOM   568  C C     . THR A 1 78  ? -10.310 32.764  -29.751 1.000 24.644  0 77   THR A C     1 ? 
ATOM   569  O O     . THR A 1 78  ? -9.532  33.691  -29.515 1.000 26.436  0 77   THR A O     1 ? 
ATOM   570  C CB    . THR A 1 78  ? -10.636 30.696  -28.328 1.000 24.482  0 77   THR A CB    1 ? 
ATOM   571  O OG1   . THR A 1 78  ? -10.325 31.521  -27.208 1.000 25.120  0 77   THR A OG1   1 ? 
ATOM   572  C CG2   . THR A 1 78  ? -10.248 29.254  -28.101 1.000 25.191  0 77   THR A CG2   1 ? 
ATOM   573  N N     . VAL A 1 79  ? -11.539 32.956  -30.196 1.000 24.712  0 78   VAL A N     1 ? 
ATOM   574  C CA    . VAL A 1 79  ? -12.208 34.222  -30.023 1.000 24.147  0 78   VAL A CA    1 ? 
ATOM   575  C C     . VAL A 1 79  ? -12.293 34.444  -28.509 1.000 25.770  0 78   VAL A C     1 ? 
ATOM   576  O O     . VAL A 1 79  ? -12.120 33.495  -27.734 1.000 23.965  0 78   VAL A O     1 ? 
ATOM   577  C CB    . VAL A 1 79  ? -13.606 34.215  -30.674 1.000 24.916  0 78   VAL A CB    1 ? 
ATOM   578  C CG1   . VAL A 1 79  ? -13.531 33.922  -32.172 1.000 28.161  0 78   VAL A CG1   1 ? 
ATOM   579  C CG2   . VAL A 1 79  ? -14.559 33.280  -29.970 1.000 24.293  0 78   VAL A CG2   1 ? 
ATOM   580  N N     . PRO A 1 80  ? -12.590 35.687  -28.053 1.000 26.919  0 79   PRO A N     1 ? 
ATOM   581  C CA    . PRO A 1 80  ? -12.779 35.951  -26.631 1.000 25.011  0 79   PRO A CA    1 ? 
ATOM   582  C C     . PRO A 1 80  ? -13.837 35.015  -26.062 1.000 24.359  0 79   PRO A C     1 ? 
ATOM   583  O O     . PRO A 1 80  ? -14.903 34.828  -26.657 1.000 24.314  0 79   PRO A O     1 ? 
ATOM   584  C CB    . PRO A 1 80  ? -13.207 37.428  -26.619 1.000 28.265  0 79   PRO A CB    1 ? 
ATOM   585  C CG    . PRO A 1 80  ? -12.602 38.004  -27.878 1.000 28.681  0 79   PRO A CG    1 ? 
ATOM   586  C CD    . PRO A 1 80  ? -12.774 36.891  -28.885 1.000 28.657  0 79   PRO A CD    1 ? 
ATOM   587  N N     . GLN A 1 81  ? -13.541 34.396  -24.907 1.000 23.501  0 80   GLN A N     1 ? 
ATOM   588  C CA    . GLN A 1 81  ? -14.467 33.443  -24.319 1.000 23.118  0 80   GLN A CA    1 ? 
ATOM   589  C C     . GLN A 1 81  ? -15.317 34.154  -23.267 1.000 24.288  0 80   GLN A C     1 ? 
ATOM   590  O O     . GLN A 1 81  ? -14.816 34.534  -22.223 1.000 20.763  0 80   GLN A O     1 ? 
ATOM   591  C CB    . GLN A 1 81  ? -13.706 32.263  -23.720 1.000 23.413  0 80   GLN A CB    1 ? 
ATOM   592  C CG    . GLN A 1 81  ? -12.981 31.412  -24.758 1.000 24.531  0 80   GLN A CG    1 ? 
ATOM   593  C CD    . GLN A 1 81  ? -13.940 30.740  -25.722 1.000 22.521  0 80   GLN A CD    1 ? 
ATOM   594  O OE1   . GLN A 1 81  ? -14.596 29.771  -25.355 1.000 22.612  0 80   GLN A OE1   1 ? 
ATOM   595  N NE2   . GLN A 1 81  ? -13.995 31.207  -26.964 1.000 23.177  0 80   GLN A NE2   1 ? 
ATOM   596  N N     . ALA A 1 82  ? -16.629 34.252  -23.523 1.000 23.969  0 81   ALA A N     1 ? 
ATOM   597  C CA    . ALA A 1 82  ? -17.513 35.103  -22.743 1.000 25.432  0 81   ALA A CA    1 ? 
ATOM   598  C C     . ALA A 1 82  ? -17.566 34.683  -21.272 1.000 25.826  0 81   ALA A C     1 ? 
ATOM   599  O O     . ALA A 1 82  ? -17.702 35.537  -20.397 1.000 25.098  0 81   ALA A O     1 ? 
ATOM   600  C CB    . ALA A 1 82  ? -18.913 35.098  -23.360 1.000 27.364  0 81   ALA A CB    1 ? 
ATOM   601  N N     . ALA A 1 83  ? -17.477 33.383  -20.979 1.000 23.700  0 82   ALA A N     1 ? 
ATOM   602  C CA    . ALA A 1 83  ? -17.562 32.899  -19.609 1.000 22.601  0 82   ALA A CA    1 ? 
ATOM   603  C C     . ALA A 1 83  ? -16.205 32.929  -18.900 1.000 22.885  0 82   ALA A C     1 ? 
ATOM   604  O O     . ALA A 1 83  ? -16.148 32.668  -17.697 1.000 24.980  0 82   ALA A O     1 ? 
ATOM   605  C CB    . ALA A 1 83  ? -18.102 31.491  -19.626 1.000 26.320  0 82   ALA A CB    1 ? 
ATOM   606  N N     . LEU A 1 84  ? -15.127 33.218  -19.639 1.000 19.305  0 83   LEU A N     1 ? 
ATOM   607  C CA    . LEU A 1 84  ? -13.780 33.341  -19.085 1.000 21.165  0 83   LEU A CA    1 ? 
ATOM   608  C C     . LEU A 1 84  ? -13.288 34.788  -19.164 1.000 21.490  0 83   LEU A C     1 ? 
ATOM   609  O O     . LEU A 1 84  ? -12.156 35.040  -19.548 1.000 22.337  0 83   LEU A O     1 ? 
ATOM   610  C CB    . LEU A 1 84  ? -12.829 32.397  -19.807 1.000 19.267  0 83   LEU A CB    1 ? 
ATOM   611  C CG    . LEU A 1 84  ? -13.240 30.923  -19.815 1.000 21.307  0 83   LEU A CG    1 ? 
ATOM   612  C CD1   . LEU A 1 84  ? -12.186 30.134  -20.588 1.000 24.617  0 83   LEU A CD1   1 ? 
ATOM   613  C CD2   . LEU A 1 84  ? -13.390 30.412  -18.420 1.000 22.317  0 83   LEU A CD2   1 ? 
ATOM   614  N N     . ASP A 1 85  ? -14.122 35.727  -18.705 1.000 22.920  0 84   ASP A N     1 ? 
ATOM   615  C CA    . ASP A 1 85  ? -13.739 37.132  -18.618 1.000 24.044  0 84   ASP A CA    1 ? 
ATOM   616  C C     . ASP A 1 85  ? -13.268 37.643  -19.984 1.000 23.128  0 84   ASP A C     1 ? 
ATOM   617  O O     . ASP A 1 85  ? -12.397 38.515  -20.049 1.000 24.034  0 84   ASP A O     1 ? 
ATOM   618  C CB    . ASP A 1 85  ? -12.702 37.360  -17.527 1.000 27.193  0 84   ASP A CB    1 ? 
ATOM   619  C CG    . ASP A 1 85  ? -13.207 37.251  -16.095 1.000 31.497  0 84   ASP A CG    1 ? 
ATOM   620  O OD1   . ASP A 1 85  ? -14.431 37.388  -15.895 1.000 31.221  0 84   ASP A OD1   1 ? 
ATOM   621  O OD2   . ASP A 1 85  ? -12.371 37.041  -15.182 1.000 35.954  0 84   ASP A OD2   1 ? 
ATOM   622  N N     . ASN A 1 86  ? -13.821 37.080  -21.072 1.000 24.592  0 85   ASN A N     1 ? 
ATOM   623  C CA    . ASN A 1 86  ? -13.499 37.484  -22.437 1.000 26.926  0 85   ASN A CA    1 ? 
ATOM   624  C C     . ASN A 1 86  ? -12.032 37.247  -22.792 1.000 26.898  0 85   ASN A C     1 ? 
ATOM   625  O O     . ASN A 1 86  ? -11.491 37.820  -23.743 1.000 26.252  0 85   ASN A O     1 ? 
ATOM   626  C CB    . ASN A 1 86  ? -13.921 38.924  -22.730 1.000 32.193  0 85   ASN A CB    1 ? 
ATOM   627  C CG    . ASN A 1 86  ? -15.421 39.037  -22.810 1.000 35.820  0 85   ASN A CG    1 ? 
ATOM   628  O OD1   . ASN A 1 86  ? -16.001 39.935  -22.199 1.000 47.089  0 85   ASN A OD1   1 ? 
ATOM   629  N ND2   . ASN A 1 86  ? -16.066 38.150  -23.554 1.000 35.538  0 85   ASN A ND2   1 ? 
ATOM   630  N N     . ARG A 1 87  ? -11.404 36.299  -22.105 1.000 22.791  0 86   ARG A N     1 ? 
ATOM   631  C CA    . ARG A 1 87  ? -10.057 35.910  -22.452 1.000 22.121  0 86   ARG A CA    1 ? 
ATOM   632  C C     . ARG A 1 87  ? -10.041 35.136  -23.766 1.000 24.587  0 86   ARG A C     1 ? 
ATOM   633  O O     . ARG A 1 87  ? -10.814 34.199  -23.927 1.000 24.772  0 86   ARG A O     1 ? 
ATOM   634  C CB    . ARG A 1 87  ? -9.457  35.016  -21.371 1.000 20.482  0 86   ARG A CB    1 ? 
ATOM   635  C CG    . ARG A 1 87  ? -9.142  35.796  -20.103 1.000 20.170  0 86   ARG A CG    1 ? 
ATOM   636  C CD    . ARG A 1 87  ? -9.044  34.868  -18.932 1.000 20.219  0 86   ARG A CD    1 ? 
ATOM   637  N NE    . ARG A 1 87  ? -8.026  33.852  -19.168 1.000 19.943  0 86   ARG A NE    1 ? 
ATOM   638  C CZ    . ARG A 1 87  ? -8.173  32.532  -18.952 1.000 19.139  0 86   ARG A CZ    1 ? 
ATOM   639  N NH1   . ARG A 1 87  ? -9.254  32.026  -18.434 1.000 19.198  0 86   ARG A NH1   1 ? 
ATOM   640  N NH2   . ARG A 1 87  ? -7.222  31.716  -19.224 1.000 20.729  0 86   ARG A NH2   1 ? 
ATOM   641  N N     . PRO A 1 88  ? -9.127  35.472  -24.701 1.000 24.792  0 87   PRO A N     1 ? 
ATOM   642  C CA    . PRO A 1 88  ? -8.825  34.603  -25.833 1.000 25.354  0 87   PRO A CA    1 ? 
ATOM   643  C C     . PRO A 1 88  ? -7.896  33.533  -25.259 1.000 28.104  0 87   PRO A C     1 ? 
ATOM   644  O O     . PRO A 1 88  ? -6.996  33.827  -24.467 1.000 32.085  0 87   PRO A O     1 ? 
ATOM   645  C CB    . PRO A 1 88  ? -8.157  35.533  -26.879 1.000 28.893  0 87   PRO A CB    1 ? 
ATOM   646  C CG    . PRO A 1 88  ? -8.225  36.931  -26.261 1.000 29.832  0 87   PRO A CG    1 ? 
ATOM   647  C CD    . PRO A 1 88  ? -8.333  36.711  -24.735 1.000 26.270  0 87   PRO A CD    1 ? 
ATOM   648  N N     . ILE A 1 89  ? -8.172  32.271  -25.578 1.000 23.812  0 88   ILE A N     1 ? 
ATOM   649  C CA    . ILE A 1 89  ? -7.447  31.156  -24.980 1.000 23.386  0 88   ILE A CA    1 ? 
ATOM   650  C C     . ILE A 1 89  ? -6.548  30.537  -26.030 1.000 22.841  0 88   ILE A C     1 ? 
ATOM   651  O O     . ILE A 1 89  ? -6.999  30.330  -27.173 1.000 21.772  0 88   ILE A O     1 ? 
ATOM   652  C CB    . ILE A 1 89  ? -8.430  30.108  -24.435 1.000 24.605  0 88   ILE A CB    1 ? 
ATOM   653  C CG1   . ILE A 1 89  ? -9.431  30.728  -23.470 1.000 25.576  0 88   ILE A CG1   1 ? 
ATOM   654  C CG2   . ILE A 1 89  ? -7.700  28.920  -23.812 1.000 27.018  0 88   ILE A CG2   1 ? 
ATOM   655  C CD1   . ILE A 1 89  ? -8.834  31.232  -22.179 1.000 25.029  0 88   ILE A CD1   1 ? 
ATOM   656  N N     . PRO A 1 90  ? -5.278  30.200  -25.692 1.000 22.549  0 89   PRO A N     1 ? 
ATOM   657  C CA    . PRO A 1 90  ? -4.396  29.526  -26.643 1.000 24.250  0 89   PRO A CA    1 ? 
ATOM   658  C C     . PRO A 1 90  ? -4.907  28.142  -27.022 1.000 23.548  0 89   PRO A C     1 ? 
ATOM   659  O O     . PRO A 1 90  ? -5.411  27.392  -26.184 1.000 20.850  0 89   PRO A O     1 ? 
ATOM   660  C CB    . PRO A 1 90  ? -3.009  29.443  -25.942 1.000 25.024  0 89   PRO A CB    1 ? 
ATOM   661  C CG    . PRO A 1 90  ? -3.136  30.342  -24.736 1.000 25.448  0 89   PRO A CG    1 ? 
ATOM   662  C CD    . PRO A 1 90  ? -4.623  30.414  -24.388 1.000 25.019  0 89   PRO A CD    1 ? 
ATOM   663  N N     . TYR A 1 91  ? -4.779  27.837  -28.315 1.000 21.825  0 90   TYR A N     1 ? 
ATOM   664  C CA    . TYR A 1 91  ? -5.054  26.531  -28.858 1.000 25.161  0 90   TYR A CA    1 ? 
ATOM   665  C C     . TYR A 1 91  ? -3.758  26.015  -29.489 1.000 24.299  0 90   TYR A C     1 ? 
ATOM   666  O O     . TYR A 1 91  ? -3.027  26.759  -30.140 1.000 25.967  0 90   TYR A O     1 ? 
ATOM   667  C CB    . TYR A 1 91  ? -6.159  26.499  -29.904 1.000 28.814  0 90   TYR A CB    1 ? 
ATOM   668  C CG    . TYR A 1 91  ? -7.413  25.779  -29.450 1.000 29.704  0 90   TYR A CG    1 ? 
ATOM   669  C CD1   . TYR A 1 91  ? -7.564  24.393  -29.527 1.000 35.546  0 90   TYR A CD1   1 ? 
ATOM   670  C CD2   . TYR A 1 91  ? -8.445  26.509  -28.916 1.000 35.578  0 90   TYR A CD2   1 ? 
ATOM   671  C CE1   . TYR A 1 91  ? -8.723  23.773  -29.075 1.000 33.017  0 90   TYR A CE1   1 ? 
ATOM   672  C CE2   . TYR A 1 91  ? -9.611  25.910  -28.498 1.000 40.028  0 90   TYR A CE2   1 ? 
ATOM   673  C CZ    . TYR A 1 91  ? -9.751  24.544  -28.563 1.000 36.507  0 90   TYR A CZ    1 ? 
ATOM   674  O OH    . TYR A 1 91  ? -10.982 24.090  -28.155 1.000 40.257  0 90   TYR A OH    1 ? 
ATOM   675  N N     . ALA A 1 92  ? -3.459  24.753  -29.233 1.000 21.709  0 91   ALA A N     1 ? 
ATOM   676  C CA    . ALA A 1 92  ? -2.324  24.072  -29.834 1.000 21.572  0 91   ALA A CA    1 ? 
ATOM   677  C C     . ALA A 1 92  ? -2.834  22.734  -30.358 1.000 22.872  0 91   ALA A C     1 ? 
ATOM   678  O O     . ALA A 1 92  ? -3.734  22.128  -29.767 1.000 20.327  0 91   ALA A O     1 ? 
ATOM   679  C CB    . ALA A 1 92  ? -1.212  23.838  -28.806 1.000 21.943  0 91   ALA A CB    1 ? 
ATOM   680  N N     . LYS A 1 93  ? -2.272  22.319  -31.492 1.000 18.930  0 92   LYS A N     1 ? 
ATOM   681  C CA    . LYS A 1 93  ? -2.411  20.969  -31.978 1.000 18.663  0 92   LYS A CA    1 ? 
ATOM   682  C C     . LYS A 1 93  ? -1.152  20.619  -32.770 1.000 18.419  0 92   LYS A C     1 ? 
ATOM   683  O O     . LYS A 1 93  ? -0.401  21.514  -33.182 1.000 20.451  0 92   LYS A O     1 ? 
ATOM   684  C CB    . LYS A 1 93  ? -3.691  20.865  -32.785 1.000 19.482  0 92   LYS A CB    1 ? 
ATOM   685  C CG    . LYS A 1 93  ? -3.644  21.607  -34.101 1.000 20.488  0 92   LYS A CG    1 ? 
ATOM   686  C CD    . LYS A 1 93  ? -5.058  21.732  -34.671 1.000 23.725  0 92   LYS A CD    1 ? 
ATOM   687  C CE    . LYS A 1 93  ? -5.118  22.305  -36.042 1.000 26.638  0 92   LYS A CE    1 ? 
ATOM   688  N NZ    . LYS A 1 93  ? -4.752  21.364  -37.125 1.000 27.252  0 92   LYS A NZ    1 ? 
ATOM   689  N N     . GLY A 1 94  ? -0.936  19.316  -32.990 1.000 17.334  0 93   GLY A N     1 ? 
ATOM   690  C CA    . GLY A 1 94  ? 0.297   18.886  -33.601 1.000 16.076  0 93   GLY A CA    1 ? 
ATOM   691  C C     . GLY A 1 94  ? 0.303   19.238  -35.092 1.000 18.757  0 93   GLY A C     1 ? 
ATOM   692  O O     . GLY A 1 94  ? -0.749  19.280  -35.717 1.000 21.350  0 93   GLY A O     1 ? 
ATOM   693  N N     . ARG A 1 95  ? 1.478   19.633  -35.584 1.000 16.905  0 94   ARG A N     1 ? 
ATOM   694  C CA    . ARG A 1 95  ? 1.679   19.901  -37.002 1.000 20.050  0 94   ARG A CA    1 ? 
ATOM   695  C C     . ARG A 1 95  ? 2.972   19.218  -37.454 1.000 19.538  0 94   ARG A C     1 ? 
ATOM   696  O O     . ARG A 1 95  ? 3.983   19.833  -37.769 1.000 19.627  0 94   ARG A O     1 ? 
ATOM   697  C CB    . ARG A 1 95  ? 1.716   21.408  -37.249 1.000 21.338  0 94   ARG A CB    1 ? 
ATOM   698  C CG    . ARG A 1 95  ? 1.765   21.841  -38.705 1.000 22.823  0 94   ARG A CG    1 ? 
ATOM   699  C CD    . ARG A 1 95  ? 1.699   23.358  -38.829 1.000 26.218  0 94   ARG A CD    1 ? 
ATOM   700  N NE    . ARG A 1 95  ? 1.459   23.728  -40.229 1.000 30.944  0 94   ARG A NE    1 ? 
ATOM   701  C CZ    . ARG A 1 95  ? 2.386   23.810  -41.165 1.000 30.529  0 94   ARG A CZ    1 ? 
ATOM   702  N NH1   . ARG A 1 95  ? 3.630   23.445  -40.921 1.000 28.374  0 94   ARG A NH1   1 ? 
ATOM   703  N NH2   . ARG A 1 95  ? 2.046   24.211  -42.376 1.000 33.069  0 94   ARG A NH2   1 ? 
ATOM   704  N N     . VAL A 1 96  ? 2.926   17.893  -37.446 1.000 20.347  0 95   VAL A N     1 ? 
ATOM   705  C CA    . VAL A 1 96  ? 4.106   17.064  -37.582 1.000 19.043  0 95   VAL A CA    1 ? 
ATOM   706  C C     . VAL A 1 96  ? 3.616   15.656  -37.901 1.000 19.174  0 95   VAL A C     1 ? 
ATOM   707  O O     . VAL A 1 96  ? 2.460   15.345  -37.671 1.000 17.891  0 95   VAL A O     1 ? 
ATOM   708  C CB    . VAL A 1 96  ? 4.944   17.101  -36.301 1.000 19.192  0 95   VAL A CB    1 ? 
ATOM   709  C CG1   . VAL A 1 96  ? 4.116   16.660  -35.103 1.000 20.522  0 95   VAL A CG1   1 ? 
ATOM   710  C CG2   . VAL A 1 96  ? 6.245   16.295  -36.408 1.000 19.317  0 95   VAL A CG2   1 ? 
ATOM   711  N N     . VAL A 1 97  ? 4.477   14.819  -38.502 1.000 18.934  0 96   VAL A N     1 ? 
ATOM   712  C CA    . VAL A 1 97  ? 4.122   13.424  -38.648 1.000 19.090  0 96   VAL A CA    1 ? 
ATOM   713  C C     . VAL A 1 97  ? 3.854   12.844  -37.272 1.000 19.272  0 96   VAL A C     1 ? 
ATOM   714  O O     . VAL A 1 97  ? 4.671   12.993  -36.363 1.000 18.307  0 96   VAL A O     1 ? 
ATOM   715  C CB    . VAL A 1 97  ? 5.195   12.635  -39.408 1.000 19.319  0 96   VAL A CB    1 ? 
ATOM   716  C CG1   . VAL A 1 97  ? 4.923   11.135  -39.360 1.000 21.260  0 96   VAL A CG1   1 ? 
ATOM   717  C CG2   . VAL A 1 97  ? 5.278   13.159  -40.846 1.000 20.305  0 96   VAL A CG2   1 ? 
ATOM   718  N N     . GLY A 1 98  ? 2.674   12.204  -37.142 1.000 16.838  0 97   GLY A N     1 ? 
ATOM   719  C CA    . GLY A 1 98  ? 2.145   11.717  -35.884 1.000 17.319  0 97   GLY A CA    1 ? 
ATOM   720  C C     . GLY A 1 98  ? 1.034   12.629  -35.346 1.000 17.050  0 97   GLY A C     1 ? 
ATOM   721  O O     . GLY A 1 98  ? 0.313   12.289  -34.405 1.000 17.795  0 97   GLY A O     1 ? 
ATOM   722  N N     . GLY A 1 99  ? 0.955   13.826  -35.919 1.000 16.975  0 98   GLY A N     1 ? 
ATOM   723  C CA    . GLY A 1 99  ? -0.009  14.825  -35.524 1.000 15.845  0 98   GLY A CA    1 ? 
ATOM   724  C C     . GLY A 1 99  ? 0.088   15.127  -34.035 1.000 14.978  0 98   GLY A C     1 ? 
ATOM   725  O O     . GLY A 1 99  ? 1.181   15.265  -33.484 1.000 16.663  0 98   GLY A O     1 ? 
ATOM   726  N N     . SER A 1 100 ? -1.063  15.160  -33.388 1.000 15.325  0 99   SER A N     1 ? 
ATOM   727  C CA    . SER A 1 100 ? -1.110  15.539  -31.978 1.000 16.425  0 99   SER A CA    1 ? 
ATOM   728  C C     . SER A 1 100 ? -0.570  14.410  -31.088 1.000 16.366  0 99   SER A C     1 ? 
ATOM   729  O O     . SER A 1 100 ? -0.170  14.668  -29.946 1.000 17.227  0 99   SER A O     1 ? 
ATOM   730  C CB    . SER A 1 100 ? -2.476  15.991  -31.550 1.000 17.724  0 99   SER A CB    1 ? 
ATOM   731  O OG    . SER A 1 100 ? -2.875  17.145  -32.269 1.000 17.716  0 99   SER A OG    1 ? 
ATOM   732  N N     . SER A 1 101 ? -0.473  13.172  -31.607 1.000 16.626  0 100  SER A N     1 ? 
ATOM   733  C CA    . SER A 1 101 ? 0.105   12.074  -30.835 1.000 16.731  0 100  SER A CA    1 ? 
ATOM   734  C C     . SER A 1 101 ? 1.625   12.236  -30.685 1.000 16.744  0 100  SER A C     1 ? 
ATOM   735  O O     . SER A 1 101 ? 2.201   11.699  -29.748 1.000 16.666  0 100  SER A O     1 ? 
ATOM   736  C CB    . SER A 1 101 ? -0.239  10.700  -31.362 1.000 18.432  0 100  SER A CB    1 ? 
ATOM   737  O OG    . SER A 1 101 ? 0.532   10.391  -32.508 1.000 17.359  0 100  SER A OG    1 ? 
ATOM   738  N N     . SER A 1 102 ? 2.245   13.046  -31.531 1.000 15.338  0 101  SER A N     1 ? 
ATOM   739  C CA    . SER A 1 102 ? 3.669   13.345  -31.466 1.000 15.901  0 101  SER A CA    1 ? 
ATOM   740  C C     . SER A 1 102 ? 3.985   14.433  -30.447 1.000 17.015  0 101  SER A C     1 ? 
ATOM   741  O O     . SER A 1 102 ? 5.151   14.597  -30.077 1.000 18.062  0 101  SER A O     1 ? 
ATOM   742  C CB    . SER A 1 102 ? 4.202   13.795  -32.800 1.000 17.757  0 101  SER A CB    1 ? 
ATOM   743  O OG    . SER A 1 102 ? 4.221   12.730  -33.726 1.000 18.339  0 101  SER A OG    1 ? 
ATOM   744  N N     . VAL A 1 103 ? 2.979   15.182  -29.999 1.000 17.839  0 102  VAL A N     1 ? 
ATOM   745  C CA    . VAL A 1 103 ? 3.222   16.314  -29.105 1.000 18.402  0 102  VAL A CA    1 ? 
ATOM   746  C C     . VAL A 1 103 ? 2.406   16.265  -27.815 1.000 18.375  0 102  VAL A C     1 ? 
ATOM   747  O O     . VAL A 1 103 ? 2.510   17.185  -27.003 1.000 16.870  0 102  VAL A O     1 ? 
ATOM   748  C CB    . VAL A 1 103 ? 2.949   17.645  -29.832 1.000 19.449  0 102  VAL A CB    1 ? 
ATOM   749  C CG1   . VAL A 1 103 ? 3.915   17.819  -30.990 1.000 21.175  0 102  VAL A CG1   1 ? 
ATOM   750  C CG2   . VAL A 1 103 ? 1.506   17.761  -30.323 1.000 18.603  0 102  VAL A CG2   1 ? 
ATOM   751  N N     . ASN A 1 104 ? 1.562   15.243  -27.656 1.000 16.743  0 103  ASN A N     1 ? 
ATOM   752  C CA    . ASN A 1 104 ? 0.617   15.200  -26.568 1.000 15.546  0 103  ASN A CA    1 ? 
ATOM   753  C C     . ASN A 1 104 ? 1.309   14.657  -25.327 1.000 15.552  0 103  ASN A C     1 ? 
ATOM   754  O O     . ASN A 1 104 ? 2.500   14.365  -25.360 1.000 16.515  0 103  ASN A O     1 ? 
ATOM   755  C CB    . ASN A 1 104 ? -0.650  14.448  -26.968 1.000 15.803  0 103  ASN A CB    1 ? 
ATOM   756  C CG    . ASN A 1 104 ? -0.496  12.954  -27.111 1.000 15.476  0 103  ASN A CG    1 ? 
ATOM   757  O OD1   . ASN A 1 104 ? 0.558   12.365  -26.881 1.000 16.146  0 103  ASN A OD1   1 ? 
ATOM   758  N ND2   . ASN A 1 104 ? -1.584  12.320  -27.500 1.000 16.170  0 103  ASN A ND2   1 ? 
ATOM   759  N N     . PHE A 1 105 ? 0.555   14.522  -24.246 1.000 15.383  0 104  PHE A N     1 ? 
ATOM   760  C CA    . PHE A 1 105 ? 1.130   14.124  -22.982 1.000 16.621  0 104  PHE A CA    1 ? 
ATOM   761  C C     . PHE A 1 105 ? 1.143   12.610  -22.774 1.000 15.024  0 104  PHE A C     1 ? 
ATOM   762  O O     . PHE A 1 105 ? 1.387   12.152  -21.642 1.000 15.109  0 104  PHE A O     1 ? 
ATOM   763  C CB    . PHE A 1 105 ? 0.395   14.922  -21.898 1.000 18.267  0 104  PHE A CB    1 ? 
ATOM   764  C CG    . PHE A 1 105 ? 0.622   16.432  -21.962 1.000 20.111  0 104  PHE A CG    1 ? 
ATOM   765  C CD1   . PHE A 1 105 ? 1.598   16.995  -22.765 1.000 21.992  0 104  PHE A CD1   1 ? 
ATOM   766  C CD2   . PHE A 1 105 ? -0.173  17.293  -21.231 1.000 27.500  0 104  PHE A CD2   1 ? 
ATOM   767  C CE1   . PHE A 1 105 ? 1.774   18.374  -22.814 1.000 22.287  0 104  PHE A CE1   1 ? 
ATOM   768  C CE2   . PHE A 1 105 ? -0.018  18.685  -21.316 1.000 27.398  0 104  PHE A CE2   1 ? 
ATOM   769  C CZ    . PHE A 1 105 ? 0.977   19.210  -22.087 1.000 23.495  0 104  PHE A CZ    1 ? 
ATOM   770  N N     . MET A 1 106 ? 0.876   11.847  -23.840 1.000 15.074  0 105  MET A N     1 ? 
ATOM   771  C CA    . MET A 1 106 ? 1.164   10.426  -23.904 1.000 16.583  0 105  MET A CA    1 ? 
ATOM   772  C C     . MET A 1 106 ? 0.227   9.550   -23.066 1.000 16.575  0 105  MET A C     1 ? 
ATOM   773  O O     . MET A 1 106 ? 0.480   8.369   -22.973 1.000 15.465  0 105  MET A O     1 ? 
ATOM   774  C CB    . MET A 1 106 ? 2.637   10.184  -23.529 1.000 15.658  0 105  MET A CB    1 ? 
ATOM   775  C CG    . MET A 1 106 ? 3.553   10.788  -24.571 1.000 17.474  0 105  MET A CG    1 ? 
ATOM   776  S SD    . MET A 1 106 ? 5.236   11.053  -23.989 1.000 19.121  0 105  MET A SD    1 ? 
ATOM   777  C CE    . MET A 1 106 ? 4.993   12.585  -23.065 1.000 17.719  0 105  MET A CE    1 ? 
ATOM   778  N N     . GLU A 1 107 ? -0.887  10.076  -22.540 1.000 16.166  0 106  GLU A N     1 ? 
ATOM   779  C CA    . GLU A 1 107 ? -1.690  9.324   -21.594 1.000 17.723  0 106  GLU A CA    1 ? 
ATOM   780  C C     . GLU A 1 107 ? -2.774  8.605   -22.383 1.000 17.542  0 106  GLU A C     1 ? 
ATOM   781  O O     . GLU A 1 107 ? -3.518  9.238   -23.123 1.000 18.329  0 106  GLU A O     1 ? 
ATOM   782  C CB    . GLU A 1 107 ? -2.264  10.194  -20.477 1.000 18.752  0 106  GLU A CB    1 ? 
ATOM   783  C CG    . GLU A 1 107 ? -1.289  11.206  -19.882 1.000 19.006  0 106  GLU A CG    1 ? 
ATOM   784  C CD    . GLU A 1 107 ? 0.062   10.710  -19.342 1.000 20.918  0 106  GLU A CD    1 ? 
ATOM   785  O OE1   . GLU A 1 107 ? 0.667   11.458  -18.506 1.000 22.119  0 106  GLU A OE1   1 ? 
ATOM   786  O OE2   . GLU A 1 107 ? 0.480   9.599   -19.722 1.000 17.885  0 106  GLU A OE2   1 ? 
ATOM   787  N N     . TYR A 1 108 ? -2.786  7.267   -22.280 1.000 16.045  0 107  TYR A N     1 ? 
ATOM   788  C CA    . TYR A 1 108 ? -3.733  6.436   -23.015 1.000 15.698  0 107  TYR A CA    1 ? 
ATOM   789  C C     . TYR A 1 108 ? -4.845  5.890   -22.123 1.000 15.567  0 107  TYR A C     1 ? 
ATOM   790  O O     . TYR A 1 108 ? -4.588  5.128   -21.172 1.000 17.649  0 107  TYR A O     1 ? 
ATOM   791  C CB    . TYR A 1 108 ? -2.935  5.298   -23.654 1.000 16.055  0 107  TYR A CB    1 ? 
ATOM   792  C CG    . TYR A 1 108 ? -3.676  4.406   -24.644 1.000 14.449  0 107  TYR A CG    1 ? 
ATOM   793  C CD1   . TYR A 1 108 ? -4.585  3.453   -24.221 1.000 15.495  0 107  TYR A CD1   1 ? 
ATOM   794  C CD2   . TYR A 1 108 ? -3.420  4.494   -25.984 1.000 15.915  0 107  TYR A CD2   1 ? 
ATOM   795  C CE1   . TYR A 1 108 ? -5.166  2.572   -25.101 1.000 15.854  0 107  TYR A CE1   1 ? 
ATOM   796  C CE2   . TYR A 1 108 ? -4.037  3.650   -26.893 1.000 17.288  0 107  TYR A CE2   1 ? 
ATOM   797  C CZ    . TYR A 1 108 ? -4.936  2.705   -26.450 1.000 17.284  0 107  TYR A CZ    1 ? 
ATOM   798  O OH    . TYR A 1 108 ? -5.522  1.834   -27.309 1.000 18.413  0 107  TYR A OH    1 ? 
ATOM   799  N N     . THR A 1 109 ? -6.066  6.350   -22.391 1.000 16.859  0 108  THR A N     1 ? 
ATOM   800  C CA    . THR A 1 109 ? -7.238  5.929   -21.639 1.000 17.936  0 108  THR A CA    1 ? 
ATOM   801  C C     . THR A 1 109 ? -8.350  5.675   -22.657 1.000 17.852  0 108  THR A C     1 ? 
ATOM   802  O O     . THR A 1 109 ? -8.855  6.614   -23.262 1.000 15.514  0 108  THR A O     1 ? 
ATOM   803  C CB    . THR A 1 109 ? -7.714  6.980   -20.632 1.000 18.000  0 108  THR A CB    1 ? 
ATOM   804  O OG1   . THR A 1 109 ? -7.857  8.208   -21.343 1.000 18.161  0 108  THR A OG1   1 ? 
ATOM   805  C CG2   . THR A 1 109 ? -6.736  7.247   -19.517 1.000 18.574  0 108  THR A CG2   1 ? 
ATOM   806  N N     . ARG A 1 110 ? -8.738  4.406   -22.827 1.000 17.985  0 109  ARG A N     1 ? 
ATOM   807  C CA    . ARG A 1 110 ? -9.709  4.024   -23.826 1.000 18.202  0 109  ARG A CA    1 ? 
ATOM   808  C C     . ARG A 1 110 ? -11.113 4.488   -23.437 1.000 18.850  0 109  ARG A C     1 ? 
ATOM   809  O O     . ARG A 1 110 ? -12.008 4.506   -24.278 1.000 20.969  0 109  ARG A O     1 ? 
ATOM   810  C CB    . ARG A 1 110 ? -9.743  2.521   -24.127 1.000 19.060  0 109  ARG A CB    1 ? 
ATOM   811  C CG    . ARG A 1 110 ? -10.125 1.665   -22.924 1.000 21.354  0 109  ARG A CG    1 ? 
ATOM   812  C CD    . ARG A 1 110 ? -10.735 0.373   -23.386 1.000 20.372  0 109  ARG A CD    1 ? 
ATOM   813  N NE    . ARG A 1 110 ? -11.074 -0.513  -22.272 1.000 19.025  0 109  ARG A NE    1 ? 
ATOM   814  C CZ    . ARG A 1 110 ? -12.333 -0.785  -21.867 1.000 18.660  0 109  ARG A CZ    1 ? 
ATOM   815  N NH1   . ARG A 1 110 ? -13.333 0.029   -22.145 1.000 18.231  0 109  ARG A NH1   1 ? 
ATOM   816  N NH2   . ARG A 1 110 ? -12.566 -1.860  -21.134 1.000 19.012  0 109  ARG A NH2   1 ? 
ATOM   817  N N     . SER A 1 111 ? -11.292 4.919   -22.181 1.000 17.493  0 110  SER A N     1 ? 
ATOM   818  C CA    . SER A 1 111 ? -12.596 5.282   -21.642 1.000 18.301  0 110  SER A CA    1 ? 
ATOM   819  C C     . SER A 1 111 ? -13.368 4.047   -21.156 1.000 18.346  0 110  SER A C     1 ? 
ATOM   820  O O     . SER A 1 111 ? -12.916 2.907   -21.269 1.000 18.809  0 110  SER A O     1 ? 
ATOM   821  C CB    . SER A 1 111 ? -13.447 6.154   -22.519 1.000 18.016  0 110  SER A CB    1 ? 
ATOM   822  O OG    . SER A 1 111 ? -14.288 6.920   -21.649 1.000 20.816  0 110  SER A OG    1 ? 
ATOM   823  N N     . SER A 1 112 ? -14.498 4.321   -20.502 1.000 20.072  0 111  SER A N     1 ? 
ATOM   824  C CA    . SER A 1 112 ? -15.359 3.286   -19.953 1.000 18.989  0 111  SER A CA    1 ? 
ATOM   825  C C     . SER A 1 112 ? -15.990 2.467   -21.072 1.000 19.210  0 111  SER A C     1 ? 
ATOM   826  O O     . SER A 1 112 ? -16.102 2.914   -22.203 1.000 18.574  0 111  SER A O     1 ? 
ATOM   827  C CB    . SER A 1 112 ? -16.449 3.876   -19.083 1.000 19.362  0 111  SER A CB    1 ? 
ATOM   828  O OG    . SER A 1 112 ? -17.246 4.786   -19.827 1.000 19.919  0 111  SER A OG    1 ? 
ATOM   829  N N     . ASN A 1 113 ? -16.488 1.289   -20.718 1.000 20.894  0 112  ASN A N     1 ? 
ATOM   830  C CA    . ASN A 1 113 ? -17.300 0.504   -21.637 1.000 19.947  0 112  ASN A CA    1 ? 
ATOM   831  C C     . ASN A 1 113 ? -18.506 1.319   -22.117 1.000 19.069  0 112  ASN A C     1 ? 
ATOM   832  O O     . ASN A 1 113 ? -18.846 1.277   -23.304 1.000 19.040  0 112  ASN A O     1 ? 
ATOM   833  C CB    . ASN A 1 113 ? -17.754 -0.800  -21.002 1.000 20.626  0 112  ASN A CB    1 ? 
ATOM   834  C CG    . ASN A 1 113 ? -16.620 -1.739  -20.699 1.000 20.041  0 112  ASN A CG    1 ? 
ATOM   835  O OD1   . ASN A 1 113 ? -15.458 -1.512  -21.060 1.000 19.400  0 112  ASN A OD1   1 ? 
ATOM   836  N ND2   . ASN A 1 113 ? -16.963 -2.848  -20.070 1.000 19.925  0 112  ASN A ND2   1 ? 
ATOM   837  N N     . THR A 1 114 ? -19.078 2.122   -21.217 1.000 17.673  0 113  THR A N     1 ? 
ATOM   838  C CA    . THR A 1 114 ? -20.261 2.932   -21.517 1.000 18.011  0 113  THR A CA    1 ? 
ATOM   839  C C     . THR A 1 114 ? -19.984 4.013   -22.549 1.000 17.420  0 113  THR A C     1 ? 
ATOM   840  O O     . THR A 1 114 ? -20.912 4.439   -23.221 1.000 17.884  0 113  THR A O     1 ? 
ATOM   841  C CB    . THR A 1 114 ? -20.886 3.510   -20.237 1.000 20.477  0 113  THR A CB    1 ? 
ATOM   842  O OG1   . THR A 1 114 ? -19.834 4.101   -19.465 1.000 18.213  0 113  THR A OG1   1 ? 
ATOM   843  C CG2   . THR A 1 114 ? -21.630 2.428   -19.465 1.000 20.167  0 113  THR A CG2   1 ? 
ATOM   844  N N     . GLU A 1 115 ? -18.727 4.455   -22.719 1.000 18.196  0 114  GLU A N     1 ? 
ATOM   845  C CA    . GLU A 1 115 ? -18.396 5.401   -23.764 1.000 18.569  0 114  GLU A CA    1 ? 
ATOM   846  C C     . GLU A 1 115 ? -18.779 4.841   -25.143 1.000 17.035  0 114  GLU A C     1 ? 
ATOM   847  O O     . GLU A 1 115 ? -19.387 5.550   -25.939 1.000 18.970  0 114  GLU A O     1 ? 
ATOM   848  C CB    . GLU A 1 115 ? -16.899 5.719   -23.731 1.000 20.426  0 114  GLU A CB    1 ? 
ATOM   849  C CG    . GLU A 1 115 ? -16.458 6.867   -24.639 1.000 19.868  0 114  GLU A CG    1 ? 
ATOM   850  C CD    . GLU A 1 115 ? -16.672 8.216   -23.967 1.000 23.502  0 114  GLU A CD    1 ? 
ATOM   851  O OE1   . GLU A 1 115 ? -16.150 8.393   -22.849 1.000 21.040  0 114  GLU A OE1   1 ? 
ATOM   852  O OE2   . GLU A 1 115 ? -17.408 9.071   -24.528 1.000 26.214  0 114  GLU A OE2   1 ? 
ATOM   853  N N     . TYR A 1 116 ? -18.408 3.589   -25.407 1.000 17.654  0 115  TYR A N     1 ? 
ATOM   854  C CA    . TYR A 1 116 ? -18.667 2.949   -26.694 1.000 17.664  0 115  TYR A CA    1 ? 
ATOM   855  C C     . TYR A 1 116 ? -20.165 2.658   -26.792 1.000 17.722  0 115  TYR A C     1 ? 
ATOM   856  O O     . TYR A 1 116 ? -20.774 2.819   -27.837 1.000 17.668  0 115  TYR A O     1 ? 
ATOM   857  C CB    . TYR A 1 116 ? -17.737 1.728   -26.885 1.000 18.460  0 115  TYR A CB    1 ? 
ATOM   858  C CG    . TYR A 1 116 ? -16.307 2.232   -26.847 1.000 18.573  0 115  TYR A CG    1 ? 
ATOM   859  C CD1   . TYR A 1 116 ? -15.730 2.760   -27.984 1.000 18.267  0 115  TYR A CD1   1 ? 
ATOM   860  C CD2   . TYR A 1 116 ? -15.591 2.328   -25.653 1.000 17.086  0 115  TYR A CD2   1 ? 
ATOM   861  C CE1   . TYR A 1 116 ? -14.466 3.342   -27.942 1.000 19.319  0 115  TYR A CE1   1 ? 
ATOM   862  C CE2   . TYR A 1 116 ? -14.321 2.875   -25.607 1.000 16.173  0 115  TYR A CE2   1 ? 
ATOM   863  C CZ    . TYR A 1 116 ? -13.759 3.420   -26.754 1.000 20.946  0 115  TYR A CZ    1 ? 
ATOM   864  O OH    . TYR A 1 116 ? -12.498 4.021   -26.761 1.000 18.378  0 115  TYR A OH    1 ? 
ATOM   865  N N     . ASP A 1 117 ? -20.777 2.238   -25.702 1.000 18.073  0 116  ASP A N     1 ? 
ATOM   866  C CA    . ASP A 1 117 ? -22.215 2.015   -25.684 1.000 19.011  0 116  ASP A CA    1 ? 
ATOM   867  C C     . ASP A 1 117 ? -22.972 3.283   -26.035 1.000 19.692  0 116  ASP A C     1 ? 
ATOM   868  O O     . ASP A 1 117 ? -23.992 3.201   -26.726 1.000 20.698  0 116  ASP A O     1 ? 
ATOM   869  C CB    . ASP A 1 117 ? -22.666 1.382   -24.379 1.000 19.937  0 116  ASP A CB    1 ? 
ATOM   870  C CG    . ASP A 1 117 ? -22.165 -0.042  -24.188 1.000 22.644  0 116  ASP A CG    1 ? 
ATOM   871  O OD1   . ASP A 1 117 ? -21.679 -0.669  -25.189 1.000 22.046  0 116  ASP A OD1   1 ? 
ATOM   872  O OD2   . ASP A 1 117 ? -22.152 -0.493  -23.025 1.000 24.691  0 116  ASP A OD2   1 ? 
ATOM   873  N N     . ARG A 1 118 ? -22.494 4.439   -25.542 1.000 17.920  0 117  ARG A N     1 ? 
ATOM   874  C CA    . ARG A 1 118 ? -23.078 5.717   -25.899 1.000 18.564  0 117  ARG A CA    1 ? 
ATOM   875  C C     . ARG A 1 118 ? -22.895 5.972   -27.404 1.000 18.958  0 117  ARG A C     1 ? 
ATOM   876  O O     . ARG A 1 118 ? -23.800 6.495   -28.026 1.000 18.160  0 117  ARG A O     1 ? 
ATOM   877  C CB    . ARG A 1 118 ? -22.551 6.854   -24.999 1.000 19.213  0 117  ARG A CB    1 ? 
ATOM   878  C CG    . ARG A 1 118 ? -23.072 8.215   -25.439 1.000 21.132  0 117  ARG A CG    1 ? 
ATOM   879  C CD    . ARG A 1 118 ? -22.837 9.350   -24.474 1.000 20.599  0 117  ARG A CD    1 ? 
ATOM   880  N NE    . ARG A 1 118 ? -21.406 9.661   -24.323 1.000 20.092  0 117  ARG A NE    1 ? 
ATOM   881  C CZ    . ARG A 1 118 ? -20.931 10.664  -23.581 1.000 20.727  0 117  ARG A CZ    1 ? 
ATOM   882  N NH1   . ARG A 1 118 ? -21.785 11.463  -22.957 1.000 21.648  0 117  ARG A NH1   1 ? 
ATOM   883  N NH2   . ARG A 1 118 ? -19.629 10.894  -23.529 1.000 19.426  0 117  ARG A NH2   1 ? 
ATOM   884  N N     . TRP A 1 119 ? -21.723 5.700   -28.001 1.000 18.544  0 118  TRP A N     1 ? 
ATOM   885  C CA    . TRP A 1 119 ? -21.597 5.838   -29.457 1.000 19.001  0 118  TRP A CA    1 ? 
ATOM   886  C C     . TRP A 1 119 ? -22.699 5.052   -30.193 1.000 19.796  0 118  TRP A C     1 ? 
ATOM   887  O O     . TRP A 1 119 ? -23.264 5.531   -31.177 1.000 20.765  0 118  TRP A O     1 ? 
ATOM   888  C CB    . TRP A 1 119 ? -20.240 5.345   -29.978 1.000 17.821  0 118  TRP A CB    1 ? 
ATOM   889  C CG    . TRP A 1 119 ? -19.057 6.192   -29.625 1.000 18.499  0 118  TRP A CG    1 ? 
ATOM   890  C CD1   . TRP A 1 119 ? -19.020 7.291   -28.822 1.000 20.298  0 118  TRP A CD1   1 ? 
ATOM   891  C CD2   . TRP A 1 119 ? -17.694 5.941   -30.043 1.000 19.390  0 118  TRP A CD2   1 ? 
ATOM   892  N NE1   . TRP A 1 119 ? -17.733 7.759   -28.742 1.000 19.971  0 118  TRP A NE1   1 ? 
ATOM   893  C CE2   . TRP A 1 119 ? -16.902 6.958   -29.472 1.000 19.157  0 118  TRP A CE2   1 ? 
ATOM   894  C CE3   . TRP A 1 119 ? -17.098 4.995   -30.881 1.000 19.316  0 118  TRP A CE3   1 ? 
ATOM   895  C CZ2   . TRP A 1 119 ? -15.530 7.017   -29.676 1.000 20.740  0 118  TRP A CZ2   1 ? 
ATOM   896  C CZ3   . TRP A 1 119 ? -15.739 5.063   -31.104 1.000 20.566  0 118  TRP A CZ3   1 ? 
ATOM   897  C CH2   . TRP A 1 119 ? -14.979 6.069   -30.516 1.000 18.933  0 118  TRP A CH2   1 ? 
ATOM   898  N N     . ALA A 1 120 ? -22.881 3.785   -29.806 1.000 20.770  0 119  ALA A N     1 ? 
ATOM   899  C CA    . ALA A 1 120 ? -23.951 2.938   -30.333 1.000 21.292  0 119  ALA A CA    1 ? 
ATOM   900  C C     . ALA A 1 120 ? -25.341 3.580   -30.186 1.000 22.385  0 119  ALA A C     1 ? 
ATOM   901  O O     . ALA A 1 120 ? -26.127 3.631   -31.143 1.000 21.292  0 119  ALA A O     1 ? 
ATOM   902  C CB    . ALA A 1 120 ? -23.918 1.575   -29.656 1.000 21.547  0 119  ALA A CB    1 ? 
ATOM   903  N N     . ASN A 1 121 ? -25.635 4.105   -28.995 1.000 21.383  0 120  ASN A N     1 ? 
ATOM   904  C CA    . ASN A 1 121 ? -26.948 4.684   -28.742 1.000 23.665  0 120  ASN A CA    1 ? 
ATOM   905  C C     . ASN A 1 121 ? -27.153 5.946   -29.578 1.000 21.986  0 120  ASN A C     1 ? 
ATOM   906  O O     . ASN A 1 121 ? -28.246 6.208   -30.076 1.000 24.675  0 120  ASN A O     1 ? 
ATOM   907  C CB    . ASN A 1 121 ? -27.146 4.951   -27.251 1.000 25.224  0 120  ASN A CB    1 ? 
ATOM   908  C CG    . ASN A 1 121 ? -27.186 3.690   -26.420 1.000 29.037  0 120  ASN A CG    1 ? 
ATOM   909  O OD1   . ASN A 1 121 ? -27.483 2.597   -26.922 1.000 30.422  0 120  ASN A OD1   1 ? 
ATOM   910  N ND2   . ASN A 1 121 ? -26.938 3.826   -25.125 1.000 31.532  0 120  ASN A ND2   1 ? 
ATOM   911  N N     . LEU A 1 122 ? -26.106 6.766   -29.732 1.000 19.754  0 121  LEU A N     1 ? 
ATOM   912  C CA    . LEU A 1 122 ? -26.237 8.024   -30.426 1.000 21.034  0 121  LEU A CA    1 ? 
ATOM   913  C C     . LEU A 1 122 ? -26.347 7.787   -31.927 1.000 22.630  0 121  LEU A C     1 ? 
ATOM   914  O O     . LEU A 1 122 ? -26.938 8.605   -32.627 1.000 26.524  0 121  LEU A O     1 ? 
ATOM   915  C CB    . LEU A 1 122 ? -25.043 8.916   -30.105 1.000 21.122  0 121  LEU A CB    1 ? 
ATOM   916  C CG    . LEU A 1 122 ? -25.032 9.522   -28.690 1.000 20.955  0 121  LEU A CG    1 ? 
ATOM   917  C CD1   . LEU A 1 122 ? -23.752 10.257  -28.434 1.000 20.072  0 121  LEU A CD1   1 ? 
ATOM   918  C CD2   . LEU A 1 122 ? -26.234 10.437  -28.537 1.000 23.459  0 121  LEU A CD2   1 ? 
ATOM   919  N N     . THR A 1 123 ? -25.736 6.709   -32.414 1.000 19.982  0 122  THR A N     1 ? 
ATOM   920  C CA    . THR A 1 123 ? -25.698 6.466   -33.853 1.000 21.739  0 122  THR A CA    1 ? 
ATOM   921  C C     . THR A 1 123 ? -26.785 5.496   -34.304 1.000 22.672  0 122  THR A C     1 ? 
ATOM   922  O O     . THR A 1 123 ? -26.983 5.344   -35.510 1.000 23.847  0 122  THR A O     1 ? 
ATOM   923  C CB    . THR A 1 123 ? -24.320 5.950   -34.273 1.000 23.107  0 122  THR A CB    1 ? 
ATOM   924  O OG1   . THR A 1 123 ? -24.053 4.712   -33.615 1.000 20.918  0 122  THR A OG1   1 ? 
ATOM   925  C CG2   . THR A 1 123 ? -23.204 6.968   -34.075 1.000 23.774  0 122  THR A CG2   1 ? 
ATOM   926  N N     . GLY A 1 124 ? -27.397 4.769   -33.365 1.000 22.783  0 123  GLY A N     1 ? 
ATOM   927  C CA    . GLY A 1 124 ? -28.243 3.630   -33.671 1.000 23.590  0 123  GLY A CA    1 ? 
ATOM   928  C C     . GLY A 1 124 ? -27.490 2.427   -34.232 1.000 25.662  0 123  GLY A C     1 ? 
ATOM   929  O O     . GLY A 1 124 ? -28.105 1.500   -34.740 1.000 26.406  0 123  GLY A O     1 ? 
ATOM   930  N N     . ASP A 1 125 ? -26.157 2.390   -34.109 1.000 24.205  0 124  ASP A N     1 ? 
ATOM   931  C CA    . ASP A 1 125 ? -25.367 1.337   -34.729 1.000 24.140  0 124  ASP A CA    1 ? 
ATOM   932  C C     . ASP A 1 125 ? -24.587 0.560   -33.675 1.000 24.121  0 124  ASP A C     1 ? 
ATOM   933  O O     . ASP A 1 125 ? -23.638 1.096   -33.120 1.000 21.447  0 124  ASP A O     1 ? 
ATOM   934  C CB    . ASP A 1 125 ? -24.468 1.973   -35.763 1.000 25.417  0 124  ASP A CB    1 ? 
ATOM   935  C CG    . ASP A 1 125 ? -23.588 1.064   -36.600 1.000 30.057  0 124  ASP A CG    1 ? 
ATOM   936  O OD1   . ASP A 1 125 ? -23.399 -0.124  -36.230 1.000 28.217  0 124  ASP A OD1   1 ? 
ATOM   937  O OD2   . ASP A 1 125 ? -23.140 1.561   -37.654 1.000 32.480  0 124  ASP A OD2   1 ? 
ATOM   938  N N     . ALA A 1 126 ? -24.926 -0.721  -33.487 1.000 22.898  0 125  ALA A N     1 ? 
ATOM   939  C CA    . ALA A 1 126 ? -24.374 -1.534  -32.409 1.000 22.496  0 125  ALA A CA    1 ? 
ATOM   940  C C     . ALA A 1 126 ? -22.916 -1.930  -32.705 1.000 22.043  0 125  ALA A C     1 ? 
ATOM   941  O O     . ALA A 1 126 ? -22.235 -2.468  -31.856 1.000 23.157  0 125  ALA A O     1 ? 
ATOM   942  C CB    . ALA A 1 126 ? -25.227 -2.760  -32.212 1.000 23.022  0 125  ALA A CB    1 ? 
ATOM   943  N N     . GLY A 1 127 ? -22.453 -1.722  -33.935 1.000 21.437  0 126  GLY A N     1 ? 
ATOM   944  C CA    . GLY A 1 127 ? -21.048 -1.902  -34.281 1.000 21.353  0 126  GLY A CA    1 ? 
ATOM   945  C C     . GLY A 1 127 ? -20.105 -0.999  -33.481 1.000 20.725  0 126  GLY A C     1 ? 
ATOM   946  O O     . GLY A 1 127 ? -18.905 -1.284  -33.419 1.000 19.911  0 126  GLY A O     1 ? 
ATOM   947  N N     . TRP A 1 128 ? -20.623 0.076   -32.868 1.000 18.698  0 127  TRP A N     1 ? 
ATOM   948  C CA    . TRP A 1 128 ? -19.796 0.971   -32.072 1.000 17.782  0 127  TRP A CA    1 ? 
ATOM   949  C C     . TRP A 1 128 ? -19.905 0.623   -30.595 1.000 18.770  0 127  TRP A C     1 ? 
ATOM   950  O O     . TRP A 1 128 ? -19.172 1.212   -29.796 1.000 19.145  0 127  TRP A O     1 ? 
ATOM   951  C CB    . TRP A 1 128 ? -20.166 2.437   -32.275 1.000 17.741  0 127  TRP A CB    1 ? 
ATOM   952  C CG    . TRP A 1 128 ? -19.853 2.940   -33.649 1.000 17.901  0 127  TRP A CG    1 ? 
ATOM   953  C CD1   . TRP A 1 128 ? -20.740 3.319   -34.612 1.000 19.923  0 127  TRP A CD1   1 ? 
ATOM   954  C CD2   . TRP A 1 128 ? -18.543 3.061   -34.225 1.000 17.395  0 127  TRP A CD2   1 ? 
ATOM   955  N NE1   . TRP A 1 128 ? -20.066 3.680   -35.746 1.000 19.107  0 127  TRP A NE1   1 ? 
ATOM   956  C CE2   . TRP A 1 128 ? -18.718 3.523   -35.543 1.000 17.302  0 127  TRP A CE2   1 ? 
ATOM   957  C CE3   . TRP A 1 128 ? -17.249 2.819   -33.760 1.000 18.177  0 127  TRP A CE3   1 ? 
ATOM   958  C CZ2   . TRP A 1 128 ? -17.642 3.755   -36.397 1.000 18.331  0 127  TRP A CZ2   1 ? 
ATOM   959  C CZ3   . TRP A 1 128 ? -16.185 3.051   -34.604 1.000 18.448  0 127  TRP A CZ3   1 ? 
ATOM   960  C CH2   . TRP A 1 128 ? -16.374 3.491   -35.914 1.000 18.251  0 127  TRP A CH2   1 ? 
ATOM   961  N N     . SER A 1 129 ? -20.753 -0.360  -30.239 1.000 18.921  0 128  SER A N     1 ? 
ATOM   962  C CA    . SER A 1 129 ? -20.899 -0.740  -28.834 1.000 16.953  0 128  SER A CA    1 ? 
ATOM   963  C C     . SER A 1 129 ? -19.597 -1.337  -28.295 1.000 18.241  0 128  SER A C     1 ? 
ATOM   964  O O     . SER A 1 129 ? -18.758 -1.851  -29.029 1.000 18.156  0 128  SER A O     1 ? 
ATOM   965  C CB    . SER A 1 129 ? -22.036 -1.735  -28.633 1.000 18.405  0 128  SER A CB    1 ? 
ATOM   966  O OG    . SER A 1 129 ? -21.660 -2.964  -29.225 1.000 20.515  0 128  SER A OG    1 ? 
ATOM   967  N N     . TRP A 1 130 ? -19.441 -1.366  -26.962 1.000 17.449  0 129  TRP A N     1 ? 
ATOM   968  C CA    . TRP A 1 130 ? -18.244 -1.976  -26.403 1.000 16.886  0 129  TRP A CA    1 ? 
ATOM   969  C C     . TRP A 1 130 ? -18.107 -3.453  -26.803 1.000 19.341  0 129  TRP A C     1 ? 
ATOM   970  O O     . TRP A 1 130 ? -17.016 -3.944  -27.058 1.000 18.183  0 129  TRP A O     1 ? 
ATOM   971  C CB    . TRP A 1 130 ? -18.187 -1.839  -24.877 1.000 17.219  0 129  TRP A CB    1 ? 
ATOM   972  C CG    . TRP A 1 130 ? -16.952 -2.507  -24.339 1.000 18.141  0 129  TRP A CG    1 ? 
ATOM   973  C CD1   . TRP A 1 130 ? -16.900 -3.566  -23.477 1.000 20.673  0 129  TRP A CD1   1 ? 
ATOM   974  C CD2   . TRP A 1 130 ? -15.588 -2.188  -24.675 1.000 19.018  0 129  TRP A CD2   1 ? 
ATOM   975  N NE1   . TRP A 1 130 ? -15.596 -3.917  -23.253 1.000 20.176  0 129  TRP A NE1   1 ? 
ATOM   976  C CE2   . TRP A 1 130 ? -14.770 -3.093  -23.977 1.000 20.939  0 129  TRP A CE2   1 ? 
ATOM   977  C CE3   . TRP A 1 130 ? -14.981 -1.217  -25.481 1.000 19.421  0 129  TRP A CE3   1 ? 
ATOM   978  C CZ2   . TRP A 1 130 ? -13.377 -3.051  -24.051 1.000 20.924  0 129  TRP A CZ2   1 ? 
ATOM   979  C CZ3   . TRP A 1 130 ? -13.607 -1.208  -25.590 1.000 20.427  0 129  TRP A CZ3   1 ? 
ATOM   980  C CH2   . TRP A 1 130 ? -12.815 -2.111  -24.891 1.000 19.518  0 129  TRP A CH2   1 ? 
ATOM   981  N N     . LYS A 1 131 ? -19.230 -4.171  -26.851 1.000 20.604  0 130  LYS A N     1 ? 
ATOM   982  C CA    . LYS A 1 131 ? -19.208 -5.569  -27.236 1.000 22.936  0 130  LYS A CA    1 ? 
ATOM   983  C C     . LYS A 1 131 ? -18.434 -5.746  -28.532 1.000 20.779  0 130  LYS A C     1 ? 
ATOM   984  O O     . LYS A 1 131 ? -17.611 -6.657  -28.640 1.000 21.621  0 130  LYS A O     1 ? 
ATOM   985  C CB    . LYS A 1 131 ? -20.635 -6.124  -27.384 1.000 28.961  0 130  LYS A CB    1 ? 
ATOM   986  C CG    . LYS A 1 131 ? -20.663 -7.643  -27.505 1.000 38.360  0 130  LYS A CG    1 ? 
ATOM   987  C CD    . LYS A 1 131 ? -22.034 -8.202  -27.863 1.000 45.351  0 130  LYS A CD    1 ? 
ATOM   988  C CE    . LYS A 1 131 ? -21.981 -9.698  -27.976 1.000 51.396  0 130  LYS A CE    1 ? 
ATOM   989  N NZ    . LYS A 1 131 ? -23.226 -10.251 -28.513 1.000 56.488  0 130  LYS A NZ    1 ? 
ATOM   990  N N     . ASN A 1 132 ? -18.670 -4.867  -29.499 1.000 19.187  0 131  ASN A N     1 ? 
ATOM   991  C CA    . ASN A 1 132 ? -18.041 -4.973  -30.811 1.000 21.154  0 131  ASN A CA    1 ? 
ATOM   992  C C     . ASN A 1 132 ? -16.701 -4.233  -30.901 1.000 19.740  0 131  ASN A C     1 ? 
ATOM   993  O O     . ASN A 1 132 ? -15.914 -4.536  -31.792 1.000 21.781  0 131  ASN A O     1 ? 
ATOM   994  C CB    . ASN A 1 132 ? -18.935 -4.400  -31.899 1.000 21.913  0 131  ASN A CB    1 ? 
ATOM   995  C CG    . ASN A 1 132 ? -18.449 -4.825  -33.268 1.000 27.173  0 131  ASN A CG    1 ? 
ATOM   996  O OD1   . ASN A 1 132 ? -18.269 -6.032  -33.478 1.000 27.154  0 131  ASN A OD1   1 ? 
ATOM   997  N ND2   . ASN A 1 132 ? -18.121 -3.895  -34.173 1.000 28.857  0 131  ASN A ND2   1 ? 
ATOM   998  N N     . MET A 1 133 ? -16.458 -3.251  -30.010 1.000 18.480  0 132  MET A N     1 ? 
ATOM   999  C CA    . MET A 1 133 ? -15.273 -2.417  -30.063 1.000 17.966  0 132  MET A CA    1 ? 
ATOM   1000 C C     . MET A 1 133 ? -14.099 -3.028  -29.304 1.000 17.994  0 132  MET A C     1 ? 
ATOM   1001 O O     . MET A 1 133 ? -12.953 -2.622  -29.519 1.000 18.010  0 132  MET A O     1 ? 
ATOM   1002 C CB    . MET A 1 133 ? -15.574 -1.009  -29.513 1.000 18.264  0 132  MET A CB    1 ? 
ATOM   1003 C CG    . MET A 1 133 ? -16.297 -0.138  -30.495 1.000 19.779  0 132  MET A CG    1 ? 
ATOM   1004 S SD    . MET A 1 133 ? -15.548 0.021   -32.133 1.000 20.702  0 132  MET A SD    1 ? 
ATOM   1005 C CE    . MET A 1 133 ? -14.139 1.059   -31.714 1.000 18.909  0 132  MET A CE    1 ? 
ATOM   1006 N N     . GLU A 1 134 ? -14.346 -3.987  -28.400 1.000 17.812  0 133  GLU A N     1 ? 
ATOM   1007 C CA    . GLU A 1 134 ? -13.265 -4.542  -27.608 1.000 19.252  0 133  GLU A CA    1 ? 
ATOM   1008 C C     . GLU A 1 134 ? -12.186 -5.138  -28.506 1.000 20.960  0 133  GLU A C     1 ? 
ATOM   1009 O O     . GLU A 1 134 ? -10.990 -4.978  -28.225 1.000 18.417  0 133  GLU A O     1 ? 
ATOM   1010 C CB    . GLU A 1 134 ? -13.824 -5.558  -26.614 1.000 20.701  0 133  GLU A CB    1 ? 
ATOM   1011 C CG    . GLU A 1 134 ? -12.716 -6.253  -25.829 1.000 24.906  0 133  GLU A CG    1 ? 
ATOM   1012 C CD    . GLU A 1 134 ? -13.199 -7.091  -24.650 1.000 29.503  0 133  GLU A CD    1 ? 
ATOM   1013 O OE1   . GLU A 1 134 ? -14.353 -7.538  -24.674 1.000 32.762  0 133  GLU A OE1   1 ? 
ATOM   1014 O OE2   . GLU A 1 134 ? -12.439 -7.222  -23.675 1.000 31.135  0 133  GLU A OE2   1 ? 
ATOM   1015 N N     . GLN A 1 135 ? -12.589 -5.748  -29.640 1.000 19.747  0 134  GLN A N     1 ? 
ATOM   1016 C CA    . GLN A 1 135 ? -11.616 -6.338  -30.537 1.000 20.181  0 134  GLN A CA    1 ? 
ATOM   1017 C C     . GLN A 1 135 ? -10.627 -5.289  -31.064 1.000 19.765  0 134  GLN A C     1 ? 
ATOM   1018 O O     . GLN A 1 135 ? -9.447  -5.597  -31.289 1.000 22.458  0 134  GLN A O     1 ? 
ATOM   1019 C CB    . GLN A 1 135 ? -12.290 -7.033  -31.719 1.000 22.399  0 134  GLN A CB    1 ? 
ATOM   1020 C CG    . GLN A 1 135 ? -13.070 -6.103  -32.636 1.000 21.028  0 134  GLN A CG    1 ? 
ATOM   1021 C CD    . GLN A 1 135 ? -13.939 -6.887  -33.593 1.000 26.567  0 134  GLN A CD    1 ? 
ATOM   1022 O OE1   . GLN A 1 135 ? -13.412 -7.694  -34.365 1.000 25.200  0 134  GLN A OE1   1 ? 
ATOM   1023 N NE2   . GLN A 1 135 ? -15.253 -6.664  -33.545 1.000 23.026  0 134  GLN A NE2   1 ? 
ATOM   1024 N N     . TYR A 1 136 ? -11.106 -4.055  -31.257 1.000 19.023  0 135  TYR A N     1 ? 
ATOM   1025 C CA    . TYR A 1 136 ? -10.296 -2.984  -31.827 1.000 19.426  0 135  TYR A CA    1 ? 
ATOM   1026 C C     . TYR A 1 136 ? -9.368  -2.402  -30.776 1.000 19.126  0 135  TYR A C     1 ? 
ATOM   1027 O O     . TYR A 1 136 ? -8.225  -2.075  -31.089 1.000 17.535  0 135  TYR A O     1 ? 
ATOM   1028 C CB    . TYR A 1 136 ? -11.129 -1.897  -32.503 1.000 20.853  0 135  TYR A CB    1 ? 
ATOM   1029 C CG    . TYR A 1 136 ? -11.879 -2.454  -33.694 1.000 19.871  0 135  TYR A CG    1 ? 
ATOM   1030 C CD1   . TYR A 1 136 ? -11.207 -2.777  -34.865 1.000 20.184  0 135  TYR A CD1   1 ? 
ATOM   1031 C CD2   . TYR A 1 136 ? -13.244 -2.726  -33.624 1.000 19.651  0 135  TYR A CD2   1 ? 
ATOM   1032 C CE1   . TYR A 1 136 ? -11.874 -3.332  -35.938 1.000 21.236  0 135  TYR A CE1   1 ? 
ATOM   1033 C CE2   . TYR A 1 136 ? -13.914 -3.307  -34.688 1.000 21.071  0 135  TYR A CE2   1 ? 
ATOM   1034 C CZ    . TYR A 1 136 ? -13.224 -3.578  -35.858 1.000 21.287  0 135  TYR A CZ    1 ? 
ATOM   1035 O OH    . TYR A 1 136 ? -13.882 -4.126  -36.932 1.000 25.527  0 135  TYR A OH    1 ? 
ATOM   1036 N N     . TYR A 1 137 ? -9.819  -2.373  -29.512 1.000 18.351  0 136  TYR A N     1 ? 
ATOM   1037 C CA    . TYR A 1 137 ? -8.922  -2.036  -28.431 1.000 16.582  0 136  TYR A CA    1 ? 
ATOM   1038 C C     . TYR A 1 137 ? -7.759  -3.028  -28.320 1.000 17.708  0 136  TYR A C     1 ? 
ATOM   1039 O O     . TYR A 1 137 ? -6.615  -2.612  -28.209 1.000 15.996  0 136  TYR A O     1 ? 
ATOM   1040 C CB    . TYR A 1 137 ? -9.750  -1.940  -27.152 1.000 17.274  0 136  TYR A CB    1 ? 
ATOM   1041 C CG    . TYR A 1 137 ? -8.900  -1.925  -25.901 1.000 18.382  0 136  TYR A CG    1 ? 
ATOM   1042 C CD1   . TYR A 1 137 ? -7.985  -0.902  -25.660 1.000 19.808  0 136  TYR A CD1   1 ? 
ATOM   1043 C CD2   . TYR A 1 137 ? -9.024  -2.925  -24.948 1.000 19.224  0 136  TYR A CD2   1 ? 
ATOM   1044 C CE1   . TYR A 1 137 ? -7.208  -0.901  -24.525 1.000 18.015  0 136  TYR A CE1   1 ? 
ATOM   1045 C CE2   . TYR A 1 137 ? -8.239  -2.945  -23.816 1.000 20.113  0 136  TYR A CE2   1 ? 
ATOM   1046 C CZ    . TYR A 1 137 ? -7.333  -1.923  -23.598 1.000 21.181  0 136  TYR A CZ    1 ? 
ATOM   1047 O OH    . TYR A 1 137 ? -6.574  -1.932  -22.457 1.000 20.965  0 136  TYR A OH    1 ? 
ATOM   1048 N N     . LEU A 1 138 ? -8.047  -4.335  -28.358 1.000 16.654  0 137  LEU A N     1 ? 
ATOM   1049 C CA    . LEU A 1 138 ? -7.012  -5.324  -28.157 1.000 17.803  0 137  LEU A CA    1 ? 
ATOM   1050 C C     . LEU A 1 138 ? -6.037  -5.322  -29.328 1.000 17.821  0 137  LEU A C     1 ? 
ATOM   1051 O O     . LEU A 1 138 ? -4.857  -5.619  -29.158 1.000 18.377  0 137  LEU A O     1 ? 
ATOM   1052 C CB    . LEU A 1 138 ? -7.690  -6.688  -27.989 1.000 19.475  0 137  LEU A CB    1 ? 
ATOM   1053 C CG    . LEU A 1 138 ? -8.534  -6.863  -26.727 1.000 20.574  0 137  LEU A CG    1 ? 
ATOM   1054 C CD1   . LEU A 1 138 ? -9.288  -8.186  -26.851 1.000 22.663  0 137  LEU A CD1   1 ? 
ATOM   1055 C CD2   . LEU A 1 138 ? -7.754  -6.790  -25.415 1.000 21.414  0 137  LEU A CD2   1 ? 
ATOM   1056 N N     . LYS A 1 139 ? -6.553  -4.970  -30.518 1.000 17.164  0 138  LYS A N     1 ? 
ATOM   1057 C CA    . LYS A 1 139 ? -5.744  -4.873  -31.714 1.000 18.950  0 138  LYS A CA    1 ? 
ATOM   1058 C C     . LYS A 1 139 ? -4.824  -3.648  -31.708 1.000 18.135  0 138  LYS A C     1 ? 
ATOM   1059 O O     . LYS A 1 139 ? -3.823  -3.636  -32.417 1.000 19.394  0 138  LYS A O     1 ? 
ATOM   1060 C CB    . LYS A 1 139 ? -6.746  -4.776  -32.869 1.000 20.689  0 138  LYS A CB    1 ? 
ATOM   1061 C CG    . LYS A 1 139 ? -6.161  -4.805  -34.214 1.000 26.286  0 138  LYS A CG    1 ? 
ATOM   1062 C CD    . LYS A 1 139 ? -7.181  -4.504  -35.303 1.000 25.039  0 138  LYS A CD    1 ? 
ATOM   1063 C CE    . LYS A 1 139 ? -6.457  -4.665  -36.555 1.000 23.764  0 138  LYS A CE    1 ? 
ATOM   1064 N NZ    . LYS A 1 139 ? -7.320  -4.701  -37.743 1.000 24.473  0 138  LYS A NZ    1 ? 
ATOM   1065 N N     . ASN A 1 140 ? -5.213  -2.598  -30.967 1.000 16.430  0 139  ASN A N     1 ? 
ATOM   1066 C CA    . ASN A 1 140 ? -4.532  -1.316  -31.024 1.000 16.478  0 139  ASN A CA    1 ? 
ATOM   1067 C C     . ASN A 1 140 ? -3.268  -1.253  -30.168 1.000 16.770  0 139  ASN A C     1 ? 
ATOM   1068 O O     . ASN A 1 140 ? -2.290  -0.603  -30.563 1.000 17.196  0 139  ASN A O     1 ? 
ATOM   1069 C CB    . ASN A 1 140 ? -5.497  -0.210  -30.631 1.000 15.544  0 139  ASN A CB    1 ? 
ATOM   1070 C CG    . ASN A 1 140 ? -4.921  1.181   -30.793 1.000 16.103  0 139  ASN A CG    1 ? 
ATOM   1071 O OD1   . ASN A 1 140 ? -4.730  1.890   -29.807 1.000 16.784  0 139  ASN A OD1   1 ? 
ATOM   1072 N ND2   . ASN A 1 140 ? -4.646  1.584   -32.024 1.000 17.899  0 139  ASN A ND2   1 ? 
ATOM   1073 N N     . SER A 1 141 ? -3.335  -1.757  -28.917 1.000 17.129  0 140  SER A N     1 ? 
ATOM   1074 C CA    . SER A 1 141 ? -2.328  -1.472  -27.911 1.000 17.874  0 140  SER A CA    1 ? 
ATOM   1075 C C     . SER A 1 141 ? -1.985  -2.735  -27.122 1.000 17.643  0 140  SER A C     1 ? 
ATOM   1076 O O     . SER A 1 141 ? -2.739  -3.720  -27.103 1.000 17.588  0 140  SER A O     1 ? 
ATOM   1077 C CB    . SER A 1 141 ? -2.756  -0.393  -26.923 1.000 19.542  0 140  SER A CB    1 ? 
ATOM   1078 O OG    . SER A 1 141 ? -4.003  -0.763  -26.347 1.000 24.180  0 140  SER A OG    1 ? 
ATOM   1079 N N     . ARG A 1 142 ? -0.850  -2.665  -26.439 1.000 16.992  0 141  ARG A N     1 ? 
ATOM   1080 C CA    . ARG A 1 142 ? -0.392  -3.719  -25.548 1.000 17.740  0 141  ARG A CA    1 ? 
ATOM   1081 C C     . ARG A 1 142 ? 0.354   -3.105  -24.366 1.000 18.973  0 141  ARG A C     1 ? 
ATOM   1082 O O     . ARG A 1 142 ? 0.879   -1.981  -24.419 1.000 19.511  0 141  ARG A O     1 ? 
ATOM   1083 C CB    . ARG A 1 142 ? 0.469   -4.704  -26.345 1.000 16.742  0 141  ARG A CB    1 ? 
ATOM   1084 C CG    . ARG A 1 142 ? 1.870   -4.215  -26.647 1.000 17.881  0 141  ARG A CG    1 ? 
ATOM   1085 C CD    . ARG A 1 142 ? 2.558   -5.125  -27.635 1.000 19.208  0 141  ARG A CD    1 ? 
ATOM   1086 N NE    . ARG A 1 142 ? 3.943   -4.721  -27.861 1.000 19.598  0 141  ARG A NE    1 ? 
ATOM   1087 C CZ    . ARG A 1 142 ? 4.392   -3.729  -28.612 1.000 24.033  0 141  ARG A CZ    1 ? 
ATOM   1088 N NH1   . ARG A 1 142 ? 3.550   -2.980  -29.286 1.000 22.921  0 141  ARG A NH1   1 ? 
ATOM   1089 N NH2   . ARG A 1 142 ? 5.702   -3.468  -28.677 1.000 24.484  0 141  ARG A NH2   1 ? 
ATOM   1090 N N     . LEU A 1 143 ? 0.398   -3.858  -23.264 1.000 18.585  0 142  LEU A N     1 ? 
ATOM   1091 C CA    . LEU A 1 143 ? 1.148   -3.452  -22.093 1.000 20.487  0 142  LEU A CA    1 ? 
ATOM   1092 C C     . LEU A 1 143 ? 2.590   -3.964  -22.188 1.000 20.846  0 142  LEU A C     1 ? 
ATOM   1093 O O     . LEU A 1 143 ? 2.833   -5.116  -22.548 1.000 20.215  0 142  LEU A O     1 ? 
ATOM   1094 C CB    . LEU A 1 143 ? 0.402   -4.057  -20.906 1.000 23.029  0 142  LEU A CB    1 ? 
ATOM   1095 C CG    . LEU A 1 143 ? 0.901   -3.632  -19.527 1.000 27.922  0 142  LEU A CG    1 ? 
ATOM   1096 C CD1   . LEU A 1 143 ? 0.703   -2.144  -19.306 1.000 26.880  0 142  LEU A CD1   1 ? 
ATOM   1097 C CD2   . LEU A 1 143 ? 0.184   -4.485  -18.470 1.000 25.001  0 142  LEU A CD2   1 ? 
ATOM   1098 N N     . VAL A 1 144 ? 3.534   -3.076  -21.885 1.000 19.055  0 143  VAL A N     1 ? 
ATOM   1099 C CA    . VAL A 1 144 ? 4.952   -3.390  -21.868 1.000 18.874  0 143  VAL A CA    1 ? 
ATOM   1100 C C     . VAL A 1 144 ? 5.497   -3.024  -20.494 1.000 20.524  0 143  VAL A C     1 ? 
ATOM   1101 O O     . VAL A 1 144 ? 4.892   -2.238  -19.776 1.000 19.855  0 143  VAL A O     1 ? 
ATOM   1102 C CB    . VAL A 1 144 ? 5.739   -2.705  -22.988 1.000 18.618  0 143  VAL A CB    1 ? 
ATOM   1103 C CG1   . VAL A 1 144 ? 5.144   -3.044  -24.348 1.000 21.421  0 143  VAL A CG1   1 ? 
ATOM   1104 C CG2   . VAL A 1 144 ? 5.796   -1.190  -22.832 1.000 20.867  0 143  VAL A CG2   1 ? 
ATOM   1105 N N     . PRO A 1 145 ? 6.629   -3.631  -20.080 1.000 22.800  0 144  PRO A N     1 ? 
ATOM   1106 C CA    . PRO A 1 145 ? 7.236   -3.344  -18.773 1.000 24.587  0 144  PRO A CA    1 ? 
ATOM   1107 C C     . PRO A 1 145 ? 7.745   -1.913  -18.669 1.000 22.429  0 144  PRO A C     1 ? 
ATOM   1108 O O     . PRO A 1 145 ? 8.044   -1.245  -19.655 1.000 21.041  0 144  PRO A O     1 ? 
ATOM   1109 C CB    . PRO A 1 145 ? 8.372   -4.387  -18.662 1.000 24.911  0 144  PRO A CB    1 ? 
ATOM   1110 C CG    . PRO A 1 145 ? 7.925   -5.448  -19.636 1.000 24.513  0 144  PRO A CG    1 ? 
ATOM   1111 C CD    . PRO A 1 145 ? 7.336   -4.697  -20.802 1.000 23.620  0 144  PRO A CD    1 ? 
ATOM   1112 N N     . PRO A 1 146 ? 7.817   -1.368  -17.442 1.000 21.679  0 145  PRO A N     1 ? 
ATOM   1113 C CA    . PRO A 1 146 ? 8.406   -0.050  -17.223 1.000 21.286  0 145  PRO A CA    1 ? 
ATOM   1114 C C     . PRO A 1 146 ? 9.886   -0.126  -17.549 1.000 21.799  0 145  PRO A C     1 ? 
ATOM   1115 O O     . PRO A 1 146 ? 10.502  -1.175  -17.388 1.000 20.373  0 145  PRO A O     1 ? 
ATOM   1116 C CB    . PRO A 1 146 ? 8.215   0.267   -15.743 1.000 23.127  0 145  PRO A CB    1 ? 
ATOM   1117 C CG    . PRO A 1 146 ? 7.634   -0.989  -15.136 1.000 24.509  0 145  PRO A CG    1 ? 
ATOM   1118 C CD    . PRO A 1 146 ? 7.464   -2.053  -16.185 1.000 23.466  0 145  PRO A CD    1 ? 
ATOM   1119 N N     . GLN A 1 147 ? 10.438  1.023   -17.924 1.000 21.606  0 146  GLN A N     1 ? 
ATOM   1120 C CA    . GLN A 1 147 ? 11.832  1.079   -18.319 1.000 21.864  0 146  GLN A CA    1 ? 
ATOM   1121 C C     . GLN A 1 147 ? 12.745  0.601   -17.196 1.000 23.090  0 146  GLN A C     1 ? 
ATOM   1122 O O     . GLN A 1 147 ? 13.725  -0.084  -17.469 1.000 26.257  0 146  GLN A O     1 ? 
ATOM   1123 C CB    . GLN A 1 147 ? 12.190  2.474   -18.817 1.000 23.299  0 146  GLN A CB    1 ? 
ATOM   1124 C CG    . GLN A 1 147 ? 13.645  2.573   -19.270 1.000 25.193  0 146  GLN A CG    1 ? 
ATOM   1125 C CD    . GLN A 1 147 ? 13.877  1.939   -20.622 1.000 26.277  0 146  GLN A CD    1 ? 
ATOM   1126 O OE1   . GLN A 1 147 ? 13.237  0.954   -21.001 1.000 25.051  0 146  GLN A OE1   1 ? 
ATOM   1127 N NE2   . GLN A 1 147 ? 14.738  2.554   -21.402 1.000 24.610  0 146  GLN A NE2   1 ? 
ATOM   1128 N N     . ASP A 1 148 ? 12.423  0.921   -15.947 1.000 21.671  0 147  ASP A N     1 ? 
ATOM   1129 C CA    . ASP A 1 148 ? 13.292  0.572   -14.830 1.000 24.078  0 147  ASP A CA    1 ? 
ATOM   1130 C C     . ASP A 1 148 ? 13.013  -0.813  -14.246 1.000 25.639  0 147  ASP A C     1 ? 
ATOM   1131 O O     . ASP A 1 148 ? 13.611  -1.168  -13.238 1.000 22.920  0 147  ASP A O     1 ? 
ATOM   1132 C CB    . ASP A 1 148 ? 13.214  1.613   -13.723 1.000 24.111  0 147  ASP A CB    1 ? 
ATOM   1133 C CG    . ASP A 1 148 ? 11.848  1.821   -13.073 1.000 24.885  0 147  ASP A CG    1 ? 
ATOM   1134 O OD1   . ASP A 1 148 ? 10.880  1.203   -13.529 1.000 24.595  0 147  ASP A OD1   1 ? 
ATOM   1135 O OD2   . ASP A 1 148 ? 11.776  2.585   -12.093 1.000 24.528  0 147  ASP A OD2   1 ? 
ATOM   1136 N N     . GLY A 1 149 ? 12.033  -1.556  -14.787 1.000 25.833  0 148  GLY A N     1 ? 
ATOM   1137 C CA    . GLY A 1 149 ? 11.728  -2.902  -14.316 1.000 24.614  0 148  GLY A CA    1 ? 
ATOM   1138 C C     . GLY A 1 149 ? 11.126  -2.933  -12.906 1.000 24.594  0 148  GLY A C     1 ? 
ATOM   1139 O O     . GLY A 1 149 ? 11.214  -3.951  -12.242 1.000 25.194  0 148  GLY A O     1 ? 
ATOM   1140 N N     . HIS A 1 150 ? 10.546  -1.826  -12.413 1.000 22.111  0 149  HIS A N     1 ? 
ATOM   1141 C CA    . HIS A 1 150 ? 10.005  -1.820  -11.068 1.000 22.086  0 149  HIS A CA    1 ? 
ATOM   1142 C C     . HIS A 1 150 ? 8.748   -2.695  -11.061 1.000 24.712  0 149  HIS A C     1 ? 
ATOM   1143 O O     . HIS A 1 150 ? 8.189   -3.022  -12.098 1.000 22.210  0 149  HIS A O     1 ? 
ATOM   1144 C CB    . HIS A 1 150 ? 9.732   -0.397  -10.587 1.000 22.693  0 149  HIS A CB    1 ? 
ATOM   1145 C CG    . HIS A 1 150 ? 8.480   0.231   -11.144 1.000 23.266  0 149  HIS A CG    1 ? 
ATOM   1146 N ND1   . HIS A 1 150 ? 8.398   0.975   -12.307 1.000 21.753  0 149  HIS A ND1   1 ? 
ATOM   1147 C CD2   . HIS A 1 150 ? 7.223   0.191   -10.643 1.000 23.952  0 149  HIS A CD2   1 ? 
ATOM   1148 C CE1   . HIS A 1 150 ? 7.134   1.371   -12.482 1.000 22.025  0 149  HIS A CE1   1 ? 
ATOM   1149 N NE2   . HIS A 1 150 ? 6.405   0.903   -11.478 1.000 24.190  0 149  HIS A NE2   1 ? 
ATOM   1150 N N     . ASN A 1 151 ? 8.354   -3.100  -9.865  1.000 23.074  0 150  ASN A N     1 ? 
ATOM   1151 C CA    . ASN A 1 151 ? 7.266   -4.028  -9.656  1.000 27.271  0 150  ASN A CA    1 ? 
ATOM   1152 C C     . ASN A 1 151 ? 5.968   -3.251  -9.788  1.000 24.108  0 150  ASN A C     1 ? 
ATOM   1153 O O     . ASN A 1 151 ? 5.710   -2.390  -8.965  1.000 23.189  0 150  ASN A O     1 ? 
ATOM   1154 C CB    . ASN A 1 151 ? 7.391   -4.660  -8.274  1.000 29.184  0 150  ASN A CB    1 ? 
ATOM   1155 C CG    . ASN A 1 151 ? 6.486   -5.861  -8.133  1.000 33.697  0 150  ASN A CG    1 ? 
ATOM   1156 O OD1   . ASN A 1 151 ? 5.395   -5.902  -8.701  1.000 29.551  0 150  ASN A OD1   1 ? 
ATOM   1157 N ND2   . ASN A 1 151 ? 6.962   -6.904  -7.478  1.000 41.362  0 150  ASN A ND2   1 ? 
ATOM   1158 N N     . THR A 1 152 ? 5.158   -3.543  -10.817 1.000 20.730  0 151  THR A N     1 ? 
ATOM   1159 C CA    . THR A 1 152 ? 3.902   -2.844  -11.033 1.000 20.174  0 151  THR A CA    1 ? 
ATOM   1160 C C     . THR A 1 152 ? 2.716   -3.620  -10.468 1.000 20.898  0 151  THR A C     1 ? 
ATOM   1161 O O     . THR A 1 152 ? 1.576   -3.287  -10.803 1.000 21.559  0 151  THR A O     1 ? 
ATOM   1162 C CB    . THR A 1 152 ? 3.689   -2.621  -12.529 1.000 20.923  0 151  THR A CB    1 ? 
ATOM   1163 O OG1   . THR A 1 152 ? 3.660   -3.919  -13.114 1.000 22.746  0 151  THR A OG1   1 ? 
ATOM   1164 C CG2   . THR A 1 152 ? 4.796   -1.779  -13.152 1.000 21.341  0 151  THR A CG2   1 ? 
ATOM   1165 N N     . THR A 1 153 ? 2.960   -4.670  -9.658  1.000 21.751  0 152  THR A N     1 ? 
ATOM   1166 C CA    . THR A 1 153 ? 1.867   -5.430  -9.074  1.000 22.433  0 152  THR A CA    1 ? 
ATOM   1167 C C     . THR A 1 153 ? 0.907   -4.466  -8.385  1.000 21.167  0 152  THR A C     1 ? 
ATOM   1168 O O     . THR A 1 153 ? 1.342   -3.672  -7.573  1.000 20.883  0 152  THR A O     1 ? 
ATOM   1169 C CB    . THR A 1 153 ? 2.363   -6.441  -8.037  1.000 23.956  0 152  THR A CB    1 ? 
ATOM   1170 O OG1   . THR A 1 153 ? 3.255   -7.323  -8.694  1.000 23.599  0 152  THR A OG1   1 ? 
ATOM   1171 C CG2   . THR A 1 153 ? 1.227   -7.209  -7.381  1.000 25.117  0 152  THR A CG2   1 ? 
ATOM   1172 N N     . GLY A 1 154 ? -0.382  -4.595  -8.659  1.000 21.352  0 153  GLY A N     1 ? 
ATOM   1173 C CA    . GLY A 1 154 ? -1.376  -3.795  -7.964  1.000 22.107  0 153  GLY A CA    1 ? 
ATOM   1174 C C     . GLY A 1 154 ? -1.639  -2.431  -8.630  1.000 22.508  0 153  GLY A C     1 ? 
ATOM   1175 O O     . GLY A 1 154 ? -2.569  -1.746  -8.212  1.000 23.848  0 153  GLY A O     1 ? 
ATOM   1176 N N     . ASP A 1 155 ? -0.909  -2.097  -9.713  1.000 21.453  0 154  ASP A N     1 ? 
ATOM   1177 C CA    . ASP A 1 155 ? -1.015  -0.784  -10.351 1.000 20.082  0 154  ASP A CA    1 ? 
ATOM   1178 C C     . ASP A 1 155 ? -1.571  -0.884  -11.773 1.000 21.030  0 154  ASP A C     1 ? 
ATOM   1179 O O     . ASP A 1 155 ? -1.827  0.140   -12.409 1.000 18.673  0 154  ASP A O     1 ? 
ATOM   1180 C CB    . ASP A 1 155 ? 0.327   -0.077  -10.429 1.000 21.332  0 154  ASP A CB    1 ? 
ATOM   1181 C CG    . ASP A 1 155 ? 1.014   0.263   -9.107  1.000 27.201  0 154  ASP A CG    1 ? 
ATOM   1182 O OD1   . ASP A 1 155 ? 0.327   0.305   -8.069  1.000 28.713  0 154  ASP A OD1   1 ? 
ATOM   1183 O OD2   . ASP A 1 155 ? 2.253   0.460   -9.125  1.000 28.981  0 154  ASP A OD2   1 ? 
ATOM   1184 N N     . VAL A 1 156 ? -1.747  -2.115  -12.260 1.000 19.336  0 155  VAL A N     1 ? 
ATOM   1185 C CA    . VAL A 1 156 ? -2.199  -2.360  -13.625 1.000 19.462  0 155  VAL A CA    1 ? 
ATOM   1186 C C     . VAL A 1 156 ? -2.726  -3.791  -13.645 1.000 23.209  0 155  VAL A C     1 ? 
ATOM   1187 O O     . VAL A 1 156 ? -2.374  -4.586  -12.759 1.000 20.564  0 155  VAL A O     1 ? 
ATOM   1188 C CB    . VAL A 1 156 ? -1.054  -2.084  -14.620 1.000 19.745  0 155  VAL A CB    1 ? 
ATOM   1189 C CG1   . VAL A 1 156 ? 0.115   -3.058  -14.580 1.000 20.864  0 155  VAL A CG1   1 ? 
ATOM   1190 C CG2   . VAL A 1 156 ? -1.538  -1.982  -16.069 1.000 21.316  0 155  VAL A CG2   1 ? 
ATOM   1191 N N     . ASP A 1 157 ? -3.568  -4.102  -14.635 1.000 21.509  0 156  ASP A N     1 ? 
ATOM   1192 C CA    . ASP A 1 157 ? -4.123  -5.437  -14.762 1.000 23.700  0 156  ASP A CA    1 ? 
ATOM   1193 C C     . ASP A 1 157 ? -3.807  -5.994  -16.140 1.000 21.651  0 156  ASP A C     1 ? 
ATOM   1194 O O     . ASP A 1 157 ? -4.519  -5.705  -17.086 1.000 20.662  0 156  ASP A O     1 ? 
ATOM   1195 C CB    . ASP A 1 157 ? -5.618  -5.453  -14.513 1.000 24.586  0 156  ASP A CB    1 ? 
ATOM   1196 C CG    . ASP A 1 157 ? -6.289  -6.819  -14.599 1.000 26.459  0 156  ASP A CG    1 ? 
ATOM   1197 O OD1   . ASP A 1 157 ? -5.585  -7.811  -14.923 1.000 25.550  0 156  ASP A OD1   1 ? 
ATOM   1198 O OD2   . ASP A 1 157 ? -7.512  -6.842  -14.381 1.000 27.589  0 156  ASP A OD2   1 ? 
ATOM   1199 N N     . PRO A 1 158 ? -2.762  -6.835  -16.294 1.000 24.151  0 157  PRO A N     1 ? 
ATOM   1200 C CA    . PRO A 1 158 ? -2.348  -7.292  -17.623 1.000 23.204  0 157  PRO A CA    1 ? 
ATOM   1201 C C     . PRO A 1 158 ? -3.463  -7.999  -18.364 1.000 22.397  0 157  PRO A C     1 ? 
ATOM   1202 O O     . PRO A 1 158 ? -3.461  -8.019  -19.584 1.000 22.369  0 157  PRO A O     1 ? 
ATOM   1203 C CB    . PRO A 1 158 ? -1.162  -8.226  -17.367 1.000 24.947  0 157  PRO A CB    1 ? 
ATOM   1204 C CG    . PRO A 1 158 ? -0.653  -7.781  -16.015 1.000 30.063  0 157  PRO A CG    1 ? 
ATOM   1205 C CD    . PRO A 1 158 ? -1.896  -7.358  -15.231 1.000 28.205  0 157  PRO A CD    1 ? 
ATOM   1206 N N     . SER A 1 159 ? -4.421  -8.569  -17.638 1.000 22.781  0 158  SER A N     1 ? 
ATOM   1207 C CA    . SER A 1 159 ? -5.485  -9.302  -18.302 1.000 27.038  0 158  SER A CA    1 ? 
ATOM   1208 C C     . SER A 1 159 ? -6.426  -8.391  -19.100 1.000 27.201  0 158  SER A C     1 ? 
ATOM   1209 O O     . SER A 1 159 ? -7.170  -8.916  -19.915 1.000 26.733  0 158  SER A O     1 ? 
ATOM   1210 C CB    . SER A 1 159 ? -6.233  -10.186 -17.334 1.000 26.554  0 158  SER A CB    1 ? 
ATOM   1211 O OG    . SER A 1 159 ? -7.081  -9.436  -16.484 1.000 31.169  0 158  SER A OG    1 ? 
ATOM   1212 N N     . VAL A 1 160 ? -6.379  -7.053  -18.943 1.000 22.504  0 159  VAL A N     1 ? 
ATOM   1213 C CA    . VAL A 1 160 ? -7.281  -6.218  -19.727 1.000 23.246  0 159  VAL A CA    1 ? 
ATOM   1214 C C     . VAL A 1 160 ? -6.543  -5.448  -20.836 1.000 21.841  0 159  VAL A C     1 ? 
ATOM   1215 O O     . VAL A 1 160 ? -7.001  -4.369  -21.225 1.000 23.387  0 159  VAL A O     1 ? 
ATOM   1216 C CB    . VAL A 1 160 ? -8.071  -5.292  -18.791 1.000 23.141  0 159  VAL A CB    1 ? 
ATOM   1217 C CG1   . VAL A 1 160 ? -8.904  -6.087  -17.795 1.000 26.690  0 159  VAL A CG1   1 ? 
ATOM   1218 C CG2   . VAL A 1 160 ? -7.200  -4.281  -18.054 1.000 23.151  0 159  VAL A CG2   1 ? 
ATOM   1219 N N     . HIS A 1 161 ? -5.388  -5.961  -21.274 1.000 18.021  0 160  HIS A N     1 ? 
ATOM   1220 C CA    . HIS A 1 161 ? -4.596  -5.346  -22.327 1.000 18.958  0 160  HIS A CA    1 ? 
ATOM   1221 C C     . HIS A 1 161 ? -4.365  -6.338  -23.467 1.000 19.951  0 160  HIS A C     1 ? 
ATOM   1222 O O     . HIS A 1 161 ? -4.211  -7.537  -23.255 1.000 20.791  0 160  HIS A O     1 ? 
ATOM   1223 C CB    . HIS A 1 161 ? -3.266  -4.824  -21.780 1.000 18.781  0 160  HIS A CB    1 ? 
ATOM   1224 C CG    . HIS A 1 161 ? -3.501  -3.698  -20.835 1.000 19.293  0 160  HIS A CG    1 ? 
ATOM   1225 N ND1   . HIS A 1 161 ? -3.559  -2.380  -21.231 1.000 18.136  0 160  HIS A ND1   1 ? 
ATOM   1226 C CD2   . HIS A 1 161 ? -3.693  -3.727  -19.505 1.000 18.992  0 160  HIS A CD2   1 ? 
ATOM   1227 C CE1   . HIS A 1 161 ? -3.807  -1.633  -20.141 1.000 20.324  0 160  HIS A CE1   1 ? 
ATOM   1228 N NE2   . HIS A 1 161 ? -3.906  -2.431  -19.072 1.000 19.208  0 160  HIS A NE2   1 ? 
ATOM   1229 N N     . GLY A 1 162 ? -4.200  -5.802  -24.670 1.000 18.842  0 161  GLY A N     1 ? 
ATOM   1230 C CA    . GLY A 1 162 ? -4.146  -6.627  -25.867 1.000 18.261  0 161  GLY A CA    1 ? 
ATOM   1231 C C     . GLY A 1 162 ? -2.739  -6.804  -26.426 1.000 17.658  0 161  GLY A C     1 ? 
ATOM   1232 O O     . GLY A 1 162 ? -1.774  -7.044  -25.692 1.000 17.988  0 161  GLY A O     1 ? 
ATOM   1233 N N     . TYR A 1 163 ? -2.666  -6.836  -27.767 1.000 16.856  0 162  TYR A N     1 ? 
ATOM   1234 C CA    . TYR A 1 163 ? -1.504  -7.354  -28.462 1.000 17.798  0 162  TYR A CA    1 ? 
ATOM   1235 C C     . TYR A 1 163 ? -1.006  -6.363  -29.505 1.000 18.868  0 162  TYR A C     1 ? 
ATOM   1236 O O     . TYR A 1 163 ? -0.139  -6.708  -30.298 1.000 19.780  0 162  TYR A O     1 ? 
ATOM   1237 C CB    . TYR A 1 163 ? -1.872  -8.717  -29.084 1.000 18.680  0 162  TYR A CB    1 ? 
ATOM   1238 C CG    . TYR A 1 163 ? -3.045  -8.690  -30.058 1.000 19.522  0 162  TYR A CG    1 ? 
ATOM   1239 C CD1   . TYR A 1 163 ? -4.355  -8.840  -29.624 1.000 21.827  0 162  TYR A CD1   1 ? 
ATOM   1240 C CD2   . TYR A 1 163 ? -2.837  -8.445  -31.418 1.000 22.942  0 162  TYR A CD2   1 ? 
ATOM   1241 C CE1   . TYR A 1 163 ? -5.430  -8.773  -30.495 1.000 22.305  0 162  TYR A CE1   1 ? 
ATOM   1242 C CE2   . TYR A 1 163 ? -3.904  -8.341  -32.295 1.000 22.185  0 162  TYR A CE2   1 ? 
ATOM   1243 C CZ    . TYR A 1 163 ? -5.193  -8.531  -31.837 1.000 23.167  0 162  TYR A CZ    1 ? 
ATOM   1244 O OH    . TYR A 1 163 ? -6.220  -8.409  -32.693 1.000 25.382  0 162  TYR A OH    1 ? 
ATOM   1245 N N     . GLY A 1 164 ? -1.539  -5.126  -29.486 1.000 17.991  0 163  GLY A N     1 ? 
ATOM   1246 C CA    . GLY A 1 164 ? -1.398  -4.227  -30.616 1.000 16.801  0 163  GLY A CA    1 ? 
ATOM   1247 C C     . GLY A 1 164 ? -0.129  -3.383  -30.581 1.000 16.816  0 163  GLY A C     1 ? 
ATOM   1248 O O     . GLY A 1 164 ? 0.659   -3.401  -29.623 1.000 18.560  0 163  GLY A O     1 ? 
ATOM   1249 N N     . PRO A 1 165 ? 0.078   -2.552  -31.634 1.000 19.230  0 164  PRO A N     1 ? 
ATOM   1250 C CA    . PRO A 1 165 ? 1.341   -1.842  -31.799 1.000 19.148  0 164  PRO A CA    1 ? 
ATOM   1251 C C     . PRO A 1 165 ? 1.604   -0.665  -30.871 1.000 18.457  0 164  PRO A C     1 ? 
ATOM   1252 O O     . PRO A 1 165 ? 2.756   -0.285  -30.713 1.000 20.069  0 164  PRO A O     1 ? 
ATOM   1253 C CB    . PRO A 1 165 ? 1.356   -1.387  -33.260 1.000 21.243  0 164  PRO A CB    1 ? 
ATOM   1254 C CG    . PRO A 1 165 ? -0.102  -1.370  -33.651 1.000 21.641  0 164  PRO A CG    1 ? 
ATOM   1255 C CD    . PRO A 1 165 ? -0.830  -2.373  -32.767 1.000 20.122  0 164  PRO A CD    1 ? 
ATOM   1256 N N     . VAL A 1 166 ? 0.555   -0.076  -30.301 1.000 17.896  0 165  VAL A N     1 ? 
ATOM   1257 C CA    . VAL A 1 166 ? 0.754   1.056   -29.423 1.000 17.809  0 165  VAL A CA    1 ? 
ATOM   1258 C C     . VAL A 1 166 ? 1.158   0.508   -28.059 1.000 16.962  0 165  VAL A C     1 ? 
ATOM   1259 O O     . VAL A 1 166 ? 0.351   -0.126  -27.395 1.000 17.687  0 165  VAL A O     1 ? 
ATOM   1260 C CB    . VAL A 1 166 ? -0.485  1.958   -29.299 1.000 16.659  0 165  VAL A CB    1 ? 
ATOM   1261 C CG1   . VAL A 1 166 ? -0.239  3.104   -28.337 1.000 18.455  0 165  VAL A CG1   1 ? 
ATOM   1262 C CG2   . VAL A 1 166 ? -0.906  2.529   -30.649 1.000 16.307  0 165  VAL A CG2   1 ? 
ATOM   1263 N N     . PRO A 1 167 ? 2.400   0.736   -27.595 1.000 19.442  0 166  PRO A N     1 ? 
ATOM   1264 C CA    . PRO A 1 167 ? 2.836   0.210   -26.301 1.000 17.572  0 166  PRO A CA    1 ? 
ATOM   1265 C C     . PRO A 1 167 ? 2.487   1.167   -25.170 1.000 17.991  0 166  PRO A C     1 ? 
ATOM   1266 O O     . PRO A 1 167 ? 2.727   2.367   -25.269 1.000 19.445  0 166  PRO A O     1 ? 
ATOM   1267 C CB    . PRO A 1 167 ? 4.356   0.073   -26.497 1.000 19.445  0 166  PRO A CB    1 ? 
ATOM   1268 C CG    . PRO A 1 167 ? 4.697   1.245   -27.391 1.000 22.719  0 166  PRO A CG    1 ? 
ATOM   1269 C CD    . PRO A 1 167 ? 3.469   1.489   -28.274 1.000 20.802  0 166  PRO A CD    1 ? 
ATOM   1270 N N     . LEU A 1 168 ? 2.007   0.593   -24.074 1.000 16.281  0 167  LEU A N     1 ? 
ATOM   1271 C CA    . LEU A 1 168 ? 1.665   1.302   -22.860 1.000 17.365  0 167  LEU A CA    1 ? 
ATOM   1272 C C     . LEU A 1 168 ? 2.561   0.782   -21.752 1.000 16.553  0 167  LEU A C     1 ? 
ATOM   1273 O O     . LEU A 1 168 ? 2.697   -0.427  -21.615 1.000 18.374  0 167  LEU A O     1 ? 
ATOM   1274 C CB    . LEU A 1 168 ? 0.209   1.074   -22.491 1.000 18.688  0 167  LEU A CB    1 ? 
ATOM   1275 C CG    . LEU A 1 168 ? -0.791  1.341   -23.612 1.000 19.473  0 167  LEU A CG    1 ? 
ATOM   1276 C CD1   . LEU A 1 168 ? -2.165  1.081   -23.017 1.000 21.017  0 167  LEU A CD1   1 ? 
ATOM   1277 C CD2   . LEU A 1 168 ? -0.694  2.729   -24.194 1.000 20.356  0 167  LEU A CD2   1 ? 
ATOM   1278 N N     . SER A 1 169 ? 3.108   1.702   -20.938 1.000 18.583  0 168  SER A N     1 ? 
ATOM   1279 C CA    . SER A 1 169 ? 3.900   1.329   -19.776 1.000 18.112  0 168  SER A CA    1 ? 
ATOM   1280 C C     . SER A 1 169 ? 3.541   2.226   -18.600 1.000 18.111  0 168  SER A C     1 ? 
ATOM   1281 O O     . SER A 1 169 ? 3.149   3.375   -18.761 1.000 17.968  0 168  SER A O     1 ? 
ATOM   1282 C CB    . SER A 1 169 ? 5.402   1.371   -20.049 1.000 18.495  0 168  SER A CB    1 ? 
ATOM   1283 O OG    . SER A 1 169 ? 5.845   2.655   -20.479 1.000 20.032  0 168  SER A OG    1 ? 
ATOM   1284 N N     . LEU A 1 170 ? 3.727   1.695   -17.390 1.000 16.222  0 169  LEU A N     1 ? 
ATOM   1285 C CA    . LEU A 1 170 ? 3.799   2.553   -16.223 1.000 17.259  0 169  LEU A CA    1 ? 
ATOM   1286 C C     . LEU A 1 170 ? 5.194   3.184   -16.183 1.000 19.433  0 169  LEU A C     1 ? 
ATOM   1287 O O     . LEU A 1 170 ? 6.111   2.745   -16.880 1.000 19.333  0 169  LEU A O     1 ? 
ATOM   1288 C CB    . LEU A 1 170 ? 3.454   1.681   -15.011 1.000 18.214  0 169  LEU A CB    1 ? 
ATOM   1289 C CG    . LEU A 1 170 ? 1.953   1.487   -14.714 1.000 23.099  0 169  LEU A CG    1 ? 
ATOM   1290 C CD1   . LEU A 1 170 ? 1.153   0.941   -15.826 1.000 27.364  0 169  LEU A CD1   1 ? 
ATOM   1291 C CD2   . LEU A 1 170 ? 1.792   0.593   -13.480 1.000 22.230  0 169  LEU A CD2   1 ? 
ATOM   1292 N N     . VAL A 1 171 ? 5.345   4.242   -15.383 1.000 18.171  0 170  VAL A N     1 ? 
ATOM   1293 C CA    . VAL A 1 171 ? 6.499   5.114   -15.523 1.000 17.457  0 170  VAL A CA    1 ? 
ATOM   1294 C C     . VAL A 1 171 ? 7.806   4.392   -15.155 1.000 17.434  0 170  VAL A C     1 ? 
ATOM   1295 O O     . VAL A 1 171 ? 7.890   3.637   -14.188 1.000 19.589  0 170  VAL A O     1 ? 
ATOM   1296 C CB    . VAL A 1 171 ? 6.283   6.418   -14.731 1.000 17.017  0 170  VAL A CB    1 ? 
ATOM   1297 C CG1   . VAL A 1 171 ? 6.342   6.219   -13.214 1.000 18.149  0 170  VAL A CG1   1 ? 
ATOM   1298 C CG2   . VAL A 1 171 ? 7.249   7.518   -15.176 1.000 18.383  0 170  VAL A CG2   1 ? 
ATOM   1299 N N     . GLY A 1 172 ? 8.845   4.710   -15.915 1.000 18.105  0 171  GLY A N     1 ? 
ATOM   1300 C CA    . GLY A 1 172 ? 10.147  4.087   -15.777 1.000 19.246  0 171  GLY A CA    1 ? 
ATOM   1301 C C     . GLY A 1 172 ? 11.153  4.876   -14.942 1.000 19.027  0 171  GLY A C     1 ? 
ATOM   1302 O O     . GLY A 1 172 ? 12.352  4.620   -15.051 1.000 20.894  0 171  GLY A O     1 ? 
ATOM   1303 N N     . THR A 1 173 ? 10.675  5.798   -14.109 1.000 19.550  0 172  THR A N     1 ? 
ATOM   1304 C CA    . THR A 1 173 ? 11.507  6.604   -13.228 1.000 21.138  0 172  THR A CA    1 ? 
ATOM   1305 C C     . THR A 1 173 ? 10.589  7.022   -12.096 1.000 21.555  0 172  THR A C     1 ? 
ATOM   1306 O O     . THR A 1 173 ? 9.430   7.341   -12.366 1.000 21.131  0 172  THR A O     1 ? 
ATOM   1307 C CB    . THR A 1 173 ? 12.054  7.796   -14.016 1.000 22.300  0 172  THR A CB    1 ? 
ATOM   1308 O OG1   . THR A 1 173 ? 13.037  8.444   -13.228 1.000 21.497  0 172  THR A OG1   1 ? 
ATOM   1309 C CG2   . THR A 1 173 ? 11.008  8.825   -14.409 1.000 21.371  0 172  THR A CG2   1 ? 
ATOM   1310 N N     . PRO A 1 174 ? 11.005  6.918   -10.822 1.000 22.314  0 173  PRO A N     1 ? 
ATOM   1311 C CA    . PRO A 1 174 ? 10.080  7.158   -9.709  1.000 24.289  0 173  PRO A CA    1 ? 
ATOM   1312 C C     . PRO A 1 174 ? 9.785   8.622   -9.404  1.000 23.639  0 173  PRO A C     1 ? 
ATOM   1313 O O     . PRO A 1 174 ? 10.488  9.529   -9.826  1.000 21.388  0 173  PRO A O     1 ? 
ATOM   1314 C CB    . PRO A 1 174 ? 10.810  6.460   -8.529  1.000 26.229  0 173  PRO A CB    1 ? 
ATOM   1315 C CG    . PRO A 1 174 ? 12.270  6.693   -8.840  1.000 25.858  0 173  PRO A CG    1 ? 
ATOM   1316 C CD    . PRO A 1 174 ? 12.342  6.459   -10.366 1.000 24.805  0 173  PRO A CD    1 ? 
ATOM   1317 N N     . ASN A 1 175 ? 8.690   8.822   -8.689  1.000 21.145  0 174  ASN A N     1 ? 
ATOM   1318 C CA    . ASN A 1 175 ? 8.262   10.127  -8.231  1.000 21.066  0 174  ASN A CA    1 ? 
ATOM   1319 C C     . ASN A 1 175 ? 7.752   9.975   -6.810  1.000 19.553  0 174  ASN A C     1 ? 
ATOM   1320 O O     . ASN A 1 175 ? 7.442   8.870   -6.366  1.000 19.979  0 174  ASN A O     1 ? 
ATOM   1321 C CB    . ASN A 1 175 ? 7.194   10.703  -9.164  1.000 20.339  0 174  ASN A CB    1 ? 
ATOM   1322 C CG    . ASN A 1 175 ? 5.955   9.835   -9.210  1.000 19.763  0 174  ASN A CG    1 ? 
ATOM   1323 O OD1   . ASN A 1 175 ? 5.145   9.853   -8.275  1.000 18.715  0 174  ASN A OD1   1 ? 
ATOM   1324 N ND2   . ASN A 1 175 ? 5.796   9.084   -10.286 1.000 20.075  0 174  ASN A ND2   1 ? 
ATOM   1325 N N     . PRO A 1 176 ? 7.561   11.079  -6.062  1.000 18.494  0 175  PRO A N     1 ? 
ATOM   1326 C CA    . PRO A 1 176 ? 7.041   10.946  -4.703  1.000 20.160  0 175  PRO A CA    1 ? 
ATOM   1327 C C     . PRO A 1 176 ? 5.520   10.884  -4.574  1.000 18.304  0 175  PRO A C     1 ? 
ATOM   1328 O O     . PRO A 1 176 ? 5.015   10.880  -3.454  1.000 21.773  0 175  PRO A O     1 ? 
ATOM   1329 C CB    . PRO A 1 176 ? 7.639   12.213  -4.053  1.000 19.272  0 175  PRO A CB    1 ? 
ATOM   1330 C CG    . PRO A 1 176 ? 7.642   13.235  -5.160  1.000 19.252  0 175  PRO A CG    1 ? 
ATOM   1331 C CD    . PRO A 1 176 ? 8.004   12.440  -6.399  1.000 19.248  0 175  PRO A CD    1 ? 
ATOM   1332 N N     . LEU A 1 177 ? 4.795   10.913  -5.704  1.000 17.890  0 176  LEU A N     1 ? 
ATOM   1333 C CA    . LEU A 1 177 ? 3.347   11.026  -5.662  1.000 18.221  0 176  LEU A CA    1 ? 
ATOM   1334 C C     . LEU A 1 177 ? 2.717   9.632   -5.614  1.000 20.862  0 176  LEU A C     1 ? 
ATOM   1335 O O     . LEU A 1 177 ? 1.707   9.448   -4.945  1.000 20.982  0 176  LEU A O     1 ? 
ATOM   1336 C CB    . LEU A 1 177 ? 2.766   11.826  -6.828  1.000 18.121  0 176  LEU A CB    1 ? 
ATOM   1337 C CG    . LEU A 1 177 ? 3.327   13.234  -7.034  1.000 16.402  0 176  LEU A CG    1 ? 
ATOM   1338 C CD1   . LEU A 1 177 ? 2.545   14.013  -8.058  1.000 16.867  0 176  LEU A CD1   1 ? 
ATOM   1339 C CD2   . LEU A 1 177 ? 3.364   14.031  -5.733  1.000 18.317  0 176  LEU A CD2   1 ? 
ATOM   1340 N N     . ASP A 1 178 ? 3.280   8.676   -6.360  1.000 19.312  0 177  ASP A N     1 ? 
ATOM   1341 C CA    . ASP A 1 178 ? 2.614   7.399   -6.574  1.000 19.687  0 177  ASP A CA    1 ? 
ATOM   1342 C C     . ASP A 1 178 ? 2.310   6.720   -5.227  1.000 19.755  0 177  ASP A C     1 ? 
ATOM   1343 O O     . ASP A 1 178 ? 1.198   6.237   -5.036  1.000 18.618  0 177  ASP A O     1 ? 
ATOM   1344 C CB    . ASP A 1 178 ? 3.398   6.560   -7.558  1.000 21.249  0 177  ASP A CB    1 ? 
ATOM   1345 C CG    . ASP A 1 178 ? 3.306   6.983   -9.028  1.000 24.790  0 177  ASP A CG    1 ? 
ATOM   1346 O OD1   . ASP A 1 178 ? 2.399   7.795   -9.366  1.000 26.583  0 177  ASP A OD1   1 ? 
ATOM   1347 O OD2   . ASP A 1 178 ? 4.114   6.486   -9.849  1.000 24.528  0 177  ASP A OD2   1 ? 
ATOM   1348 N N     . ALA A 1 179 ? 3.284   6.670   -4.306  1.000 20.167  0 178  ALA A N     1 ? 
ATOM   1349 C CA    . ALA A 1 179 ? 3.081   5.927   -3.066  1.000 20.165  0 178  ALA A CA    1 ? 
ATOM   1350 C C     . ALA A 1 179 ? 2.072   6.638   -2.184  1.000 20.645  0 178  ALA A C     1 ? 
ATOM   1351 O O     . ALA A 1 179 ? 1.331   5.977   -1.461  1.000 20.684  0 178  ALA A O     1 ? 
ATOM   1352 C CB    . ALA A 1 179 ? 4.365   5.658   -2.317  1.000 23.008  0 178  ALA A CB    1 ? 
ATOM   1353 N N     . ARG A 1 180 ? 2.065   7.975   -2.214  1.000 21.499  0 179  ARG A N     1 ? 
ATOM   1354 C CA    . ARG A 1 180 ? 1.085   8.726   -1.442  1.000 21.913  0 179  ARG A CA    1 ? 
ATOM   1355 C C     . ARG A 1 180 ? -0.303  8.537   -2.046  1.000 21.366  0 179  ARG A C     1 ? 
ATOM   1356 O O     . ARG A 1 180 ? -1.263  8.429   -1.311  1.000 19.498  0 179  ARG A O     1 ? 
ATOM   1357 C CB    . ARG A 1 180 ? 1.408   10.219  -1.342  1.000 23.393  0 179  ARG A CB    1 ? 
ATOM   1358 C CG    . ARG A 1 180 ? 2.670   10.386  -0.497  1.000 22.605  0 179  ARG A CG    1 ? 
ATOM   1359 C CD    . ARG A 1 180 ? 3.101   11.818  -0.439  1.000 23.962  0 179  ARG A CD    1 ? 
ATOM   1360 N NE    . ARG A 1 180 ? 4.162   11.974  0.564   1.000 27.873  0 179  ARG A NE    1 ? 
ATOM   1361 C CZ    . ARG A 1 180 ? 5.459   11.729  0.379   1.000 30.568  0 179  ARG A CZ    1 ? 
ATOM   1362 N NH1   . ARG A 1 180 ? 5.970   11.436  -0.821  1.000 25.274  0 179  ARG A NH1   1 ? 
ATOM   1363 N NH2   . ARG A 1 180 ? 6.258   11.840  1.423   1.000 30.170  0 179  ARG A NH2   1 ? 
ATOM   1364 N N     . MET A 1 181 ? -0.414  8.531   -3.381  1.000 17.894  0 180  MET A N     1 ? 
ATOM   1365 C CA    . MET A 1 181 ? -1.690  8.280   -4.021  1.000 17.476  0 180  MET A CA    1 ? 
ATOM   1366 C C     . MET A 1 181 ? -2.231  6.908   -3.628  1.000 18.252  0 180  MET A C     1 ? 
ATOM   1367 O O     . MET A 1 181 ? -3.397  6.796   -3.260  1.000 19.814  0 180  MET A O     1 ? 
ATOM   1368 C CB    . MET A 1 181 ? -1.551  8.332   -5.554  1.000 16.937  0 180  MET A CB    1 ? 
ATOM   1369 C CG    . MET A 1 181 ? -2.845  8.241   -6.255  1.000 18.367  0 180  MET A CG    1 ? 
ATOM   1370 S SD    . MET A 1 181 ? -2.694  8.032   -8.044  1.000 21.499  0 180  MET A SD    1 ? 
ATOM   1371 C CE    . MET A 1 181 ? -2.626  6.244   -8.006  1.000 21.120  0 180  MET A CE    1 ? 
ATOM   1372 N N     . ARG A 1 182 ? -1.378  5.876   -3.671  1.000 18.258  0 181  ARG A N     1 ? 
ATOM   1373 C CA    . ARG A 1 182 ? -1.809  4.531   -3.308  1.000 21.504  0 181  ARG A CA    1 ? 
ATOM   1374 C C     . ARG A 1 182 ? -2.289  4.493   -1.859  1.000 21.076  0 181  ARG A C     1 ? 
ATOM   1375 O O     . ARG A 1 182 ? -3.325  3.915   -1.552  1.000 20.405  0 181  ARG A O     1 ? 
ATOM   1376 C CB    . ARG A 1 182 ? -0.672  3.509   -3.412  1.000 22.144  0 181  ARG A CB    1 ? 
ATOM   1377 C CG    . ARG A 1 182 ? -0.246  3.124   -4.817  1.000 23.556  0 181  ARG A CG    1 ? 
ATOM   1378 C CD    . ARG A 1 182 ? 0.854   2.045   -4.666  1.000 25.250  0 181  ARG A CD    1 ? 
ATOM   1379 N NE    . ARG A 1 182 ? 1.542   1.987   -5.956  1.000 31.086  0 181  ARG A NE    1 ? 
ATOM   1380 C CZ    . ARG A 1 182 ? 2.693   2.584   -6.299  1.000 32.228  0 181  ARG A CZ    1 ? 
ATOM   1381 N NH1   . ARG A 1 182 ? 3.473   3.208   -5.426  1.000 30.355  0 181  ARG A NH1   1 ? 
ATOM   1382 N NH2   . ARG A 1 182 ? 3.076   2.511   -7.557  1.000 31.540  0 181  ARG A NH2   1 ? 
ATOM   1383 N N     . ALA A 1 183 ? -1.498  5.082   -0.960  1.000 20.549  0 182  ALA A N     1 ? 
ATOM   1384 C CA    . ALA A 1 183 ? -1.809  5.019   0.469   1.000 22.041  0 182  ALA A CA    1 ? 
ATOM   1385 C C     . ALA A 1 183 ? -3.134  5.734   0.751   1.000 23.387  0 182  ALA A C     1 ? 
ATOM   1386 O O     . ALA A 1 183 ? -3.955  5.242   1.531   1.000 21.444  0 182  ALA A O     1 ? 
ATOM   1387 C CB    . ALA A 1 183 ? -0.672  5.595   1.288   1.000 21.408  0 182  ALA A CB    1 ? 
ATOM   1388 N N     . ALA A 1 184 ? -3.371  6.878   0.088   1.000 19.185  0 183  ALA A N     1 ? 
ATOM   1389 C CA    . ALA A 1 184 ? -4.561  7.682   0.330   1.000 19.280  0 183  ALA A CA    1 ? 
ATOM   1390 C C     . ALA A 1 184 ? -5.825  7.007   -0.202  1.000 19.980  0 183  ALA A C     1 ? 
ATOM   1391 O O     . ALA A 1 184 ? -6.910  7.309   0.300   1.000 21.493  0 183  ALA A O     1 ? 
ATOM   1392 C CB    . ALA A 1 184 ? -4.395  9.062   -0.307  1.000 20.158  0 183  ALA A CB    1 ? 
ATOM   1393 N N     . THR A 1 185 ? -5.701  6.144   -1.245  1.000 20.134  0 184  THR A N     1 ? 
ATOM   1394 C CA    . THR A 1 185 ? -6.866  5.678   -2.009  1.000 18.750  0 184  THR A CA    1 ? 
ATOM   1395 C C     . THR A 1 185 ? -7.175  4.203   -1.758  1.000 19.482  0 184  THR A C     1 ? 
ATOM   1396 O O     . THR A 1 185 ? -8.326  3.794   -1.954  1.000 20.968  0 184  THR A O     1 ? 
ATOM   1397 C CB    . THR A 1 185 ? -6.720  5.935   -3.520  1.000 18.988  0 184  THR A CB    1 ? 
ATOM   1398 O OG1   . THR A 1 185 ? -5.601  5.208   -4.006  1.000 18.121  0 184  THR A OG1   1 ? 
ATOM   1399 C CG2   . THR A 1 185 ? -6.526  7.406   -3.845  1.000 18.425  0 184  THR A CG2   1 ? 
ATOM   1400 N N     . GLN A 1 186 ? -6.164  3.428   -1.377  1.000 19.279  0 185  GLN A N     1 ? 
ATOM   1401 C CA    . GLN A 1 186 ? -6.302  1.999   -1.134  1.000 21.532  0 185  GLN A CA    1 ? 
ATOM   1402 C C     . GLN A 1 186 ? -6.744  1.735   0.308   1.000 25.462  0 185  GLN A C     1 ? 
ATOM   1403 O O     . GLN A 1 186 ? -7.199  0.634   0.629   1.000 26.650  0 185  GLN A O     1 ? 
ATOM   1404 C CB    . GLN A 1 186 ? -4.974  1.293   -1.427  1.000 21.777  0 185  GLN A CB    1 ? 
ATOM   1405 C CG    . GLN A 1 186 ? -4.632  1.297   -2.916  1.000 21.900  0 185  GLN A CG    1 ? 
ATOM   1406 C CD    . GLN A 1 186 ? -3.315  0.650   -3.281  1.000 26.578  0 185  GLN A CD    1 ? 
ATOM   1407 O OE1   . GLN A 1 186 ? -2.941  0.586   -4.457  1.000 28.140  0 185  GLN A OE1   1 ? 
ATOM   1408 N NE2   . GLN A 1 186 ? -2.563  0.186   -2.298  1.000 22.759  0 185  GLN A NE2   1 ? 
ATOM   1409 N N     . ALA A 1 187 ? -6.614  2.739   1.171   1.000 25.476  0 186  ALA A N     1 ? 
ATOM   1410 C CA    . ALA A 1 187 ? -7.018  2.593   2.567   1.000 29.224  0 186  ALA A CA    1 ? 
ATOM   1411 C C     . ALA A 1 187 ? -8.515  2.272   2.683   1.000 28.572  0 186  ALA A C     1 ? 
ATOM   1412 O O     . ALA A 1 187 ? -9.373  2.839   1.979   1.000 23.709  0 186  ALA A O     1 ? 
ATOM   1413 C CB    . ALA A 1 187 ? -6.707  3.872   3.310   1.000 30.300  0 186  ALA A CB    1 ? 
ATOM   1414 N N     . PRO A 1 188 ? -8.904  1.406   3.651   1.000 30.522  0 187  PRO A N     1 ? 
ATOM   1415 C CA    . PRO A 1 188 ? -10.320 1.205   3.963   1.000 27.813  0 187  PRO A CA    1 ? 
ATOM   1416 C C     . PRO A 1 188 ? -10.903 2.579   4.254   1.000 27.093  0 187  PRO A C     1 ? 
ATOM   1417 O O     . PRO A 1 188 ? -10.277 3.407   4.912   1.000 30.947  0 187  PRO A O     1 ? 
ATOM   1418 C CB    . PRO A 1 188 ? -10.323 0.266   5.211   1.000 31.095  0 187  PRO A CB    1 ? 
ATOM   1419 C CG    . PRO A 1 188 ? -8.956  -0.384  5.203   1.000 33.367  0 187  PRO A CG    1 ? 
ATOM   1420 C CD    . PRO A 1 188 ? -8.022  0.633   4.551   1.000 34.754  0 187  PRO A CD    1 ? 
ATOM   1421 N N     . GLY A 1 189 ? -12.078 2.821   3.697   1.000 26.630  0 188  GLY A N     1 ? 
ATOM   1422 C CA    . GLY A 1 189 ? -12.800 4.049   3.962   1.000 33.408  0 188  GLY A CA    1 ? 
ATOM   1423 C C     . GLY A 1 189 ? -12.233 5.276   3.237   1.000 32.818  0 188  GLY A C     1 ? 
ATOM   1424 O O     . GLY A 1 189 ? -12.741 6.368   3.464   1.000 33.043  0 188  GLY A O     1 ? 
ATOM   1425 N N     . ALA A 1 190 ? -11.202 5.123   2.386   1.000 30.874  0 189  ALA A N     1 ? 
ATOM   1426 C CA    . ALA A 1 190 ? -10.674 6.257   1.627   1.000 25.084  0 189  ALA A CA    1 ? 
ATOM   1427 C C     . ALA A 1 190 ? -11.823 7.004   0.961   1.000 23.255  0 189  ALA A C     1 ? 
ATOM   1428 O O     . ALA A 1 190 ? -12.692 6.420   0.315   1.000 24.336  0 189  ALA A O     1 ? 
ATOM   1429 C CB    . ALA A 1 190 ? -9.642  5.802   0.612   1.000 25.363  0 189  ALA A CB    1 ? 
ATOM   1430 N N     . GLU A 1 191 ? -11.774 8.334   1.032   1.000 22.212  0 190  GLU A N     1 ? 
ATOM   1431 C CA    . GLU A 1 191 ? -12.772 9.171   0.393   1.000 24.721  0 190  GLU A CA    1 ? 
ATOM   1432 C C     . GLU A 1 191 ? -12.681 9.016   -1.123  1.000 22.351  0 190  GLU A C     1 ? 
ATOM   1433 O O     . GLU A 1 191 ? -13.688 9.066   -1.806  1.000 22.934  0 190  GLU A O     1 ? 
ATOM   1434 C CB    . GLU A 1 191 ? -12.510 10.640  0.746   1.000 27.321  0 190  GLU A CB    1 ? 
ATOM   1435 C CG    . GLU A 1 191 ? -13.584 11.625  0.272   1.000 34.220  0 190  GLU A CG    1 ? 
ATOM   1436 C CD    . GLU A 1 191 ? -13.261 13.101  0.589   1.000 40.501  0 190  GLU A CD    1 ? 
ATOM   1437 O OE1   . GLU A 1 191 ? -13.856 14.031  -0.052  1.000 38.820  0 190  GLU A OE1   1 ? 
ATOM   1438 O OE2   . GLU A 1 191 ? -12.346 13.341  1.435   1.000 36.947  0 190  GLU A OE2   1 ? 
ATOM   1439 N N     . PHE A 1 192 ? -11.456 8.915   -1.645  1.000 19.499  0 191  PHE A N     1 ? 
ATOM   1440 C CA    . PHE A 1 192 ? -11.232 8.730   -3.085  1.000 18.810  0 191  PHE A CA    1 ? 
ATOM   1441 C C     . PHE A 1 192 ? -10.692 7.320   -3.306  1.000 20.254  0 191  PHE A C     1 ? 
ATOM   1442 O O     . PHE A 1 192 ? -9.602  7.019   -2.864  1.000 21.704  0 191  PHE A O     1 ? 
ATOM   1443 C CB    . PHE A 1 192 ? -10.233 9.782   -3.574  1.000 19.224  0 191  PHE A CB    1 ? 
ATOM   1444 C CG    . PHE A 1 192 ? -10.709 11.208  -3.365  1.000 22.233  0 191  PHE A CG    1 ? 
ATOM   1445 C CD1   . PHE A 1 192 ? -10.541 11.852  -2.141  1.000 22.432  0 191  PHE A CD1   1 ? 
ATOM   1446 C CD2   . PHE A 1 192 ? -11.384 11.881  -4.376  1.000 22.783  0 191  PHE A CD2   1 ? 
ATOM   1447 C CE1   . PHE A 1 192 ? -11.014 13.139  -1.953  1.000 23.927  0 191  PHE A CE1   1 ? 
ATOM   1448 C CE2   . PHE A 1 192 ? -11.876 13.166  -4.170  1.000 24.294  0 191  PHE A CE2   1 ? 
ATOM   1449 C CZ    . PHE A 1 192 ? -11.704 13.785  -2.959  1.000 24.582  0 191  PHE A CZ    1 ? 
ATOM   1450 N N     . PRO A 1 193 ? -11.436 6.389   -3.942  1.000 21.699  0 192  PRO A N     1 ? 
ATOM   1451 C CA    . PRO A 1 193 ? -10.971 5.015   -4.094  1.000 20.232  0 192  PRO A CA    1 ? 
ATOM   1452 C C     . PRO A 1 193 ? -9.824  4.870   -5.085  1.000 21.409  0 192  PRO A C     1 ? 
ATOM   1453 O O     . PRO A 1 193 ? -9.595  5.761   -5.904  1.000 20.381  0 192  PRO A O     1 ? 
ATOM   1454 C CB    . PRO A 1 193 ? -12.214 4.272   -4.575  1.000 21.083  0 192  PRO A CB    1 ? 
ATOM   1455 C CG    . PRO A 1 193 ? -12.992 5.313   -5.299  1.000 22.680  0 192  PRO A CG    1 ? 
ATOM   1456 C CD    . PRO A 1 193 ? -12.795 6.567   -4.464  1.000 22.502  0 192  PRO A CD    1 ? 
ATOM   1457 N N     . PHE A 1 194 ? -9.207  3.686   -5.067  1.000 20.029  0 193  PHE A N     1 ? 
ATOM   1458 C CA    . PHE A 1 194 ? -8.134  3.330   -5.996  1.000 19.148  0 193  PHE A CA    1 ? 
ATOM   1459 C C     . PHE A 1 194 ? -8.671  2.559   -7.198  1.000 20.498  0 193  PHE A C     1 ? 
ATOM   1460 O O     . PHE A 1 194 ? -9.606  1.783   -7.063  1.000 20.371  0 193  PHE A O     1 ? 
ATOM   1461 C CB    . PHE A 1 194 ? -7.126  2.494   -5.231  1.000 21.451  0 193  PHE A CB    1 ? 
ATOM   1462 C CG    . PHE A 1 194 ? -5.972  2.049   -6.095  1.000 21.115  0 193  PHE A CG    1 ? 
ATOM   1463 C CD1   . PHE A 1 194 ? -4.990  2.952   -6.484  1.000 21.757  0 193  PHE A CD1   1 ? 
ATOM   1464 C CD2   . PHE A 1 194 ? -5.887  0.732   -6.523  1.000 22.069  0 193  PHE A CD2   1 ? 
ATOM   1465 C CE1   . PHE A 1 194 ? -3.942  2.541   -7.283  1.000 23.231  0 193  PHE A CE1   1 ? 
ATOM   1466 C CE2   . PHE A 1 194 ? -4.823  0.331   -7.309  1.000 21.588  0 193  PHE A CE2   1 ? 
ATOM   1467 C CZ    . PHE A 1 194 ? -3.859  1.235   -7.679  1.000 22.555  0 193  PHE A CZ    1 ? 
ATOM   1468 N N     . GLN A 1 195 ? -8.075  2.789   -8.374  1.000 18.733  0 194  GLN A N     1 ? 
ATOM   1469 C CA    . GLN A 1 195 ? -8.468  2.089   -9.598  1.000 20.004  0 194  GLN A CA    1 ? 
ATOM   1470 C C     . GLN A 1 195 ? -7.278  1.278   -10.104 1.000 18.863  0 194  GLN A C     1 ? 
ATOM   1471 O O     . GLN A 1 195 ? -6.291  1.849   -10.583 1.000 18.629  0 194  GLN A O     1 ? 
ATOM   1472 C CB    . GLN A 1 195 ? -8.903  3.074   -10.688 1.000 20.834  0 194  GLN A CB    1 ? 
ATOM   1473 C CG    . GLN A 1 195 ? -9.317  2.397   -11.996 1.000 20.141  0 194  GLN A CG    1 ? 
ATOM   1474 C CD    . GLN A 1 195 ? -10.277 1.235   -11.782 1.000 21.573  0 194  GLN A CD    1 ? 
ATOM   1475 O OE1   . GLN A 1 195 ? -9.950  0.086   -12.088 1.000 21.793  0 194  GLN A OE1   1 ? 
ATOM   1476 N NE2   . GLN A 1 195 ? -11.467 1.517   -11.262 1.000 22.032  0 194  GLN A NE2   1 ? 
ATOM   1477 N N     . LEU A 1 196 ? -7.404  -0.061  -10.023 1.000 21.423  0 195  LEU A N     1 ? 
ATOM   1478 C CA    . LEU A 1 196 ? -6.355  -1.000  -10.429 1.000 19.292  0 195  LEU A CA    1 ? 
ATOM   1479 C C     . LEU A 1 196 ? -5.967  -0.805  -11.896 1.000 19.044  0 195  LEU A C     1 ? 
ATOM   1480 O O     . LEU A 1 196 ? -4.792  -0.862  -12.236 1.000 19.909  0 195  LEU A O     1 ? 
ATOM   1481 C CB    . LEU A 1 196 ? -6.860  -2.429  -10.223 1.000 20.100  0 195  LEU A CB    1 ? 
ATOM   1482 C CG    . LEU A 1 196 ? -5.941  -3.534  -10.758 1.000 22.798  0 195  LEU A CG    1 ? 
ATOM   1483 C CD1   . LEU A 1 196 ? -4.559  -3.479  -10.147 1.000 24.282  0 195  LEU A CD1   1 ? 
ATOM   1484 C CD2   . LEU A 1 196 ? -6.590  -4.902  -10.603 1.000 26.391  0 195  LEU A CD2   1 ? 
ATOM   1485 N N     . ASP A 1 197 ? -6.970  -0.599  -12.746 1.000 19.238  0 196  ASP A N     1 ? 
ATOM   1486 C CA    . ASP A 1 197 ? -6.712  -0.445  -14.175 1.000 18.738  0 196  ASP A CA    1 ? 
ATOM   1487 C C     . ASP A 1 197 ? -7.875  0.259   -14.866 1.000 18.219  0 196  ASP A C     1 ? 
ATOM   1488 O O     . ASP A 1 197 ? -8.891  -0.335  -15.223 1.000 18.330  0 196  ASP A O     1 ? 
ATOM   1489 C CB    . ASP A 1 197 ? -6.291  -1.747  -14.835 1.000 19.484  0 196  ASP A CB    1 ? 
ATOM   1490 C CG    . ASP A 1 197 ? -5.644  -1.573  -16.203 1.000 19.238  0 196  ASP A CG    1 ? 
ATOM   1491 O OD1   . ASP A 1 197 ? -6.059  -0.606  -16.912 1.000 18.183  0 196  ASP A OD1   1 ? 
ATOM   1492 O OD2   . ASP A 1 197 ? -4.698  -2.345  -16.519 1.000 19.493  0 196  ASP A OD2   1 ? 
ATOM   1493 N N     . MET A 1 198 ? -7.648  1.543   -15.114 1.000 18.413  0 197  MET A N     1 ? 
ATOM   1494 C CA    . MET A 1 198 ? -8.614  2.438   -15.711 1.000 18.224  0 197  MET A CA    1 ? 
ATOM   1495 C C     . MET A 1 198 ? -8.905  2.058   -17.164 1.000 18.213  0 197  MET A C     1 ? 
ATOM   1496 O O     . MET A 1 198 ? -9.857  2.580   -17.753 1.000 18.506  0 197  MET A O     1 ? 
ATOM   1497 C CB    . MET A 1 198 ? -8.116  3.885   -15.636 1.000 18.354  0 197  MET A CB    1 ? 
ATOM   1498 C CG    . MET A 1 198 ? -6.875  4.146   -16.492 1.000 20.052  0 197  MET A CG    1 ? 
ATOM   1499 S SD    . MET A 1 198 ? -6.245  5.805   -16.222 1.000 25.289  0 197  MET A SD    1 ? 
ATOM   1500 C CE    . MET A 1 198 ? -5.560  5.656   -14.560 1.000 22.958  0 197  MET A CE    1 ? 
ATOM   1501 N N     . ASN A 1 199 ? -8.106  1.160   -17.727 1.000 17.710  0 198  ASN A N     1 ? 
ATOM   1502 C CA    . ASN A 1 199 ? -8.371  0.685   -19.078 1.000 16.158  0 198  ASN A CA    1 ? 
ATOM   1503 C C     . ASN A 1 199 ? -9.095  -0.665  -19.035 1.000 17.575  0 198  ASN A C     1 ? 
ATOM   1504 O O     . ASN A 1 199 ? -9.245  -1.324  -20.065 1.000 16.927  0 198  ASN A O     1 ? 
ATOM   1505 C CB    . ASN A 1 199 ? -7.073  0.649   -19.848 1.000 16.197  0 198  ASN A CB    1 ? 
ATOM   1506 C CG    . ASN A 1 199 ? -6.734  1.994   -20.418 1.000 17.378  0 198  ASN A CG    1 ? 
ATOM   1507 O OD1   . ASN A 1 199 ? -7.621  2.701   -20.905 1.000 19.897  0 198  ASN A OD1   1 ? 
ATOM   1508 N ND2   . ASN A 1 199 ? -5.474  2.389   -20.301 1.000 16.679  0 198  ASN A ND2   1 ? 
ATOM   1509 N N     . GLY A 1 200 ? -9.625  -1.050  -17.874 1.000 17.620  0 199  GLY A N     1 ? 
ATOM   1510 C CA    . GLY A 1 200 ? -10.374 -2.298  -17.798 1.000 19.936  0 199  GLY A CA    1 ? 
ATOM   1511 C C     . GLY A 1 200 ? -11.893 -2.136  -17.791 1.000 20.116  0 199  GLY A C     1 ? 
ATOM   1512 O O     . GLY A 1 200 ? -12.608 -3.126  -17.548 1.000 21.055  0 199  GLY A O     1 ? 
ATOM   1513 N N     . GLY A 1 201 ? -12.404 -0.931  -18.085 1.000 18.712  0 200  GLY A N     1 ? 
ATOM   1514 C CA    . GLY A 1 201 ? -13.841 -0.782  -18.271 1.000 20.159  0 200  GLY A CA    1 ? 
ATOM   1515 C C     . GLY A 1 201 ? -14.501 0.202   -17.321 1.000 20.137  0 200  GLY A C     1 ? 
ATOM   1516 O O     . GLY A 1 201 ? -15.546 0.779   -17.668 1.000 19.098  0 200  GLY A O     1 ? 
ATOM   1517 N N     . ASP A 1 202 ? -13.909 0.337   -16.124 1.000 21.497  0 201  ASP A N     1 ? 
ATOM   1518 C CA    . ASP A 1 202 ? -14.332 1.276   -15.098 1.000 21.287  0 201  ASP A CA    1 ? 
ATOM   1519 C C     . ASP A 1 202 ? -13.164 2.216   -14.754 1.000 20.409  0 201  ASP A C     1 ? 
ATOM   1520 O O     . ASP A 1 202 ? -12.067 1.771   -14.430 1.000 20.262  0 201  ASP A O     1 ? 
ATOM   1521 C CB    . ASP A 1 202 ? -14.741 0.479   -13.870 1.000 23.311  0 201  ASP A CB    1 ? 
ATOM   1522 C CG    . ASP A 1 202 ? -15.220 1.277   -12.669 1.000 26.998  0 201  ASP A CG    1 ? 
ATOM   1523 O OD1   . ASP A 1 202 ? -15.464 2.467   -12.817 1.000 25.741  0 201  ASP A OD1   1 ? 
ATOM   1524 O OD2   . ASP A 1 202 ? -15.313 0.689   -11.571 1.000 32.384  0 201  ASP A OD2   1 ? 
ATOM   1525 N N     . MET A 1 203 ? -13.392 3.524   -14.840 1.000 18.394  0 202  MET A N     1 ? 
ATOM   1526 C CA    . MET A 1 203 ? -12.320 4.480   -14.668 1.000 18.089  0 202  MET A CA    1 ? 
ATOM   1527 C C     . MET A 1 203 ? -12.354 5.069   -13.259 1.000 18.420  0 202  MET A C     1 ? 
ATOM   1528 O O     . MET A 1 203 ? -11.407 5.738   -12.867 1.000 18.642  0 202  MET A O     1 ? 
ATOM   1529 C CB    . MET A 1 203 ? -12.436 5.618   -15.683 1.000 18.141  0 202  MET A CB    1 ? 
ATOM   1530 C CG    . MET A 1 203 ? -12.249 5.137   -17.079 1.000 20.127  0 202  MET A CG    1 ? 
ATOM   1531 S SD    . MET A 1 203 ? -12.074 6.543   -18.180 1.000 23.994  0 202  MET A SD    1 ? 
ATOM   1532 C CE    . MET A 1 203 ? -10.324 6.847   -17.895 1.000 20.157  0 202  MET A CE    1 ? 
ATOM   1533 N N     . ILE A 1 204 ? -13.438 4.848   -12.519 1.000 18.297  0 203  ILE A N     1 ? 
ATOM   1534 C CA    . ILE A 1 204 ? -13.647 5.572   -11.274 1.000 20.517  0 203  ILE A CA    1 ? 
ATOM   1535 C C     . ILE A 1 204 ? -12.537 5.247   -10.285 1.000 20.290  0 203  ILE A C     1 ? 
ATOM   1536 O O     . ILE A 1 204 ? -12.201 4.081   -10.045 1.000 19.583  0 203  ILE A O     1 ? 
ATOM   1537 C CB    . ILE A 1 204 ? -15.034 5.325   -10.655 1.000 20.799  0 203  ILE A CB    1 ? 
ATOM   1538 C CG1   . ILE A 1 204 ? -16.165 5.666   -11.604 1.000 20.128  0 203  ILE A CG1   1 ? 
ATOM   1539 C CG2   . ILE A 1 204 ? -15.194 6.078   -9.334  1.000 21.019  0 203  ILE A CG2   1 ? 
ATOM   1540 C CD1   . ILE A 1 204 ? -16.185 7.078   -12.152 1.000 20.015  0 203  ILE A CD1   1 ? 
ATOM   1541 N N     . GLY A 1 205 ? -12.012 6.318   -9.668  1.000 20.768  0 204  GLY A N     1 ? 
ATOM   1542 C CA    . GLY A 1 205 ? -10.931 6.230   -8.700  1.000 20.585  0 204  GLY A CA    1 ? 
ATOM   1543 C C     . GLY A 1 205 ? -9.620  6.756   -9.274  1.000 20.217  0 204  GLY A C     1 ? 
ATOM   1544 O O     . GLY A 1 205 ? -9.583  7.212   -10.422 1.000 18.181  0 204  GLY A O     1 ? 
ATOM   1545 N N     . PHE A 1 206 ? -8.585  6.746   -8.429  1.000 18.357  0 205  PHE A N     1 ? 
ATOM   1546 C CA    . PHE A 1 206 ? -7.247  7.156   -8.798  1.000 17.775  0 205  PHE A CA    1 ? 
ATOM   1547 C C     . PHE A 1 206 ? -6.444  5.947   -9.259  1.000 19.648  0 205  PHE A C     1 ? 
ATOM   1548 O O     . PHE A 1 206 ? -6.357  4.978   -8.531  1.000 18.435  0 205  PHE A O     1 ? 
ATOM   1549 C CB    . PHE A 1 206 ? -6.517  7.789   -7.624  1.000 19.752  0 205  PHE A CB    1 ? 
ATOM   1550 C CG    . PHE A 1 206 ? -6.716  9.281   -7.533  1.000 18.003  0 205  PHE A CG    1 ? 
ATOM   1551 C CD1   . PHE A 1 206 ? -6.004  10.135  -8.362  1.000 19.369  0 205  PHE A CD1   1 ? 
ATOM   1552 C CD2   . PHE A 1 206 ? -7.603  9.807   -6.623  1.000 19.433  0 205  PHE A CD2   1 ? 
ATOM   1553 C CE1   . PHE A 1 206 ? -6.158  11.514  -8.259  1.000 20.437  0 205  PHE A CE1   1 ? 
ATOM   1554 C CE2   . PHE A 1 206 ? -7.753  11.172  -6.511  1.000 20.629  0 205  PHE A CE2   1 ? 
ATOM   1555 C CZ    . PHE A 1 206 ? -7.031  12.028  -7.334  1.000 20.353  0 205  PHE A CZ    1 ? 
ATOM   1556 N N     . GLY A 1 207 ? -5.877  6.018   -10.464 1.000 18.648  0 206  GLY A N     1 ? 
ATOM   1557 C CA    . GLY A 1 207 ? -4.986  4.994   -10.984 1.000 19.112  0 206  GLY A CA    1 ? 
ATOM   1558 C C     . GLY A 1 207 ? -3.660  5.592   -11.430 1.000 17.660  0 206  GLY A C     1 ? 
ATOM   1559 O O     . GLY A 1 207 ? -3.589  6.806   -11.707 1.000 17.171  0 206  GLY A O     1 ? 
ATOM   1560 N N     . ILE A 1 208 ? -2.653  4.710   -11.551 1.000 18.583  0 207  ILE A N     1 ? 
ATOM   1561 C CA    . ILE A 1 208 ? -1.325  5.069   -12.013 1.000 17.611  0 207  ILE A CA    1 ? 
ATOM   1562 C C     . ILE A 1 208 ? -1.428  5.193   -13.534 1.000 17.968  0 207  ILE A C     1 ? 
ATOM   1563 O O     . ILE A 1 208 ? -1.953  4.316   -14.212 1.000 18.214  0 207  ILE A O     1 ? 
ATOM   1564 C CB    . ILE A 1 208 ? -0.277  4.008   -11.619 1.000 17.435  0 207  ILE A CB    1 ? 
ATOM   1565 C CG1   . ILE A 1 208 ? -0.188  3.805   -10.098 1.000 20.647  0 207  ILE A CG1   1 ? 
ATOM   1566 C CG2   . ILE A 1 208 ? 1.095   4.293   -12.211 1.000 18.862  0 207  ILE A CG2   1 ? 
ATOM   1567 C CD1   . ILE A 1 208 ? 0.373   4.995   -9.356  1.000 21.791  0 207  ILE A CD1   1 ? 
ATOM   1568 N N     . VAL A 1 209 ? -0.937  6.296   -14.068 1.000 17.268  0 208  VAL A N     1 ? 
ATOM   1569 C CA    . VAL A 1 209 ? -1.135  6.565   -15.492 1.000 17.903  0 208  VAL A CA    1 ? 
ATOM   1570 C C     . VAL A 1 209 ? -0.386  5.543   -16.355 1.000 16.750  0 208  VAL A C     1 ? 
ATOM   1571 O O     . VAL A 1 209 ? 0.689   5.052   -16.007 1.000 16.846  0 208  VAL A O     1 ? 
ATOM   1572 C CB    . VAL A 1 209 ? -0.752  8.038   -15.774 1.000 18.266  0 208  VAL A CB    1 ? 
ATOM   1573 C CG1   . VAL A 1 209 ? 0.758   8.268   -15.708 1.000 20.206  0 208  VAL A CG1   1 ? 
ATOM   1574 C CG2   . VAL A 1 209 ? -1.333  8.515   -17.089 1.000 20.478  0 208  VAL A CG2   1 ? 
ATOM   1575 N N     . GLN A 1 210 ? -0.946  5.278   -17.548 1.000 17.585  0 209  GLN A N     1 ? 
ATOM   1576 C CA    . GLN A 1 210 ? -0.376  4.383   -18.543 1.000 17.579  0 209  GLN A CA    1 ? 
ATOM   1577 C C     . GLN A 1 210 ? -0.046  5.197   -19.790 1.000 16.943  0 209  GLN A C     1 ? 
ATOM   1578 O O     . GLN A 1 210 ? -0.909  5.900   -20.247 1.000 16.996  0 209  GLN A O     1 ? 
ATOM   1579 C CB    . GLN A 1 210 ? -1.375  3.270   -18.876 1.000 18.124  0 209  GLN A CB    1 ? 
ATOM   1580 C CG    . GLN A 1 210 ? -1.782  2.426   -17.671 1.000 17.936  0 209  GLN A CG    1 ? 
ATOM   1581 C CD    . GLN A 1 210 ? -2.979  1.536   -17.953 1.000 19.127  0 209  GLN A CD    1 ? 
ATOM   1582 O OE1   . GLN A 1 210 ? -3.249  1.180   -19.098 1.000 18.200  0 209  GLN A OE1   1 ? 
ATOM   1583 N NE2   . GLN A 1 210 ? -3.688  1.149   -16.915 1.000 19.729  0 209  GLN A NE2   1 ? 
ATOM   1584 N N     . SER A 1 211 ? 1.243   5.249   -20.182 1.000 17.122  0 210  SER A N     1 ? 
ATOM   1585 C CA    . SER A 1 211 ? 1.733   6.194   -21.185 1.000 17.441  0 210  SER A CA    1 ? 
ATOM   1586 C C     . SER A 1 211 ? 2.235   5.456   -22.423 1.000 16.423  0 210  SER A C     1 ? 
ATOM   1587 O O     . SER A 1 211 ? 2.780   4.337   -22.298 1.000 15.838  0 210  SER A O     1 ? 
ATOM   1588 C CB    . SER A 1 211 ? 2.826   7.062   -20.632 1.000 18.728  0 210  SER A CB    1 ? 
ATOM   1589 O OG    . SER A 1 211 ? 2.431   7.668   -19.391 1.000 20.280  0 210  SER A OG    1 ? 
ATOM   1590 N N     . THR A 1 212 ? 2.206   6.148   -23.586 1.000 15.065  0 211  THR A N     1 ? 
ATOM   1591 C CA    . THR A 1 212 ? 2.645   5.542   -24.828 1.000 15.461  0 211  THR A CA    1 ? 
ATOM   1592 C C     . THR A 1 212 ? 4.169   5.660   -24.943 1.000 16.392  0 211  THR A C     1 ? 
ATOM   1593 O O     . THR A 1 212 ? 4.684   6.457   -25.722 1.000 17.269  0 211  THR A O     1 ? 
ATOM   1594 C CB    . THR A 1 212 ? 1.945   6.216   -26.009 1.000 17.574  0 211  THR A CB    1 ? 
ATOM   1595 O OG1   . THR A 1 212 ? 2.248   7.614   -25.951 1.000 18.296  0 211  THR A OG1   1 ? 
ATOM   1596 C CG2   . THR A 1 212 ? 0.446   5.985   -26.004 1.000 19.005  0 211  THR A CG2   1 ? 
ATOM   1597 N N     . ILE A 1 213 ? 4.878   4.909   -24.109 1.000 17.500  0 212  ILE A N     1 ? 
ATOM   1598 C CA    . ILE A 1 213 ? 6.330   5.042   -23.944 1.000 16.760  0 212  ILE A CA    1 ? 
ATOM   1599 C C     . ILE A 1 213 ? 6.886   3.630   -23.820 1.000 18.438  0 212  ILE A C     1 ? 
ATOM   1600 O O     . ILE A 1 213 ? 6.406   2.866   -22.996 1.000 19.522  0 212  ILE A O     1 ? 
ATOM   1601 C CB    . ILE A 1 213 ? 6.690   5.846   -22.666 1.000 16.466  0 212  ILE A CB    1 ? 
ATOM   1602 C CG1   . ILE A 1 213 ? 6.120   7.260   -22.719 1.000 15.900  0 212  ILE A CG1   1 ? 
ATOM   1603 C CG2   . ILE A 1 213 ? 8.205   5.887   -22.391 1.000 19.210  0 212  ILE A CG2   1 ? 
ATOM   1604 C CD1   . ILE A 1 213 ? 6.265   8.036   -21.433 1.000 16.625  0 212  ILE A CD1   1 ? 
ATOM   1605 N N     . LEU A 1 214 ? 7.875   3.345   -24.658 1.000 18.629  0 213  LEU A N     1 ? 
ATOM   1606 C CA    . LEU A 1 214 ? 8.607   2.101   -24.708 1.000 18.408  0 213  LEU A CA    1 ? 
ATOM   1607 C C     . LEU A 1 214 ? 10.084  2.428   -24.877 1.000 18.239  0 213  LEU A C     1 ? 
ATOM   1608 O O     . LEU A 1 214 ? 10.435  3.262   -25.712 1.000 17.410  0 213  LEU A O     1 ? 
ATOM   1609 C CB    . LEU A 1 214 ? 8.092   1.301   -25.904 1.000 18.880  0 213  LEU A CB    1 ? 
ATOM   1610 C CG    . LEU A 1 214 ? 8.853   0.011   -26.213 1.000 22.186  0 213  LEU A CG    1 ? 
ATOM   1611 C CD1   . LEU A 1 214 ? 8.787   -0.940  -25.023 1.000 23.194  0 213  LEU A CD1   1 ? 
ATOM   1612 C CD2   . LEU A 1 214 ? 8.282   -0.598  -27.464 1.000 22.702  0 213  LEU A CD2   1 ? 
ATOM   1613 N N     . ASN A 1 215 ? 10.947  1.737   -24.130 1.000 19.149  0 214  ASN A N     1 ? 
ATOM   1614 C CA    . ASN A 1 215 ? 12.377  2.028   -24.126 1.000 19.177  0 214  ASN A CA    1 ? 
ATOM   1615 C C     . ASN A 1 215 ? 12.636  3.527   -23.877 1.000 19.907  0 214  ASN A C     1 ? 
ATOM   1616 O O     . ASN A 1 215 ? 13.561  4.124   -24.453 1.000 21.686  0 214  ASN A O     1 ? 
ATOM   1617 C CB    . ASN A 1 215 ? 13.035  1.574   -25.424 1.000 21.278  0 214  ASN A CB    1 ? 
ATOM   1618 C CG    . ASN A 1 215 ? 14.545  1.468   -25.289 1.000 26.303  0 214  ASN A CG    1 ? 
ATOM   1619 O OD1   . ASN A 1 215 ? 15.100  1.240   -24.197 1.000 26.745  0 214  ASN A OD1   1 ? 
ATOM   1620 N ND2   . ASN A 1 215 ? 15.233  1.647   -26.405 1.000 27.267  0 214  ASN A ND2   1 ? 
ATOM   1621 N N     . GLY A 1 216 ? 11.829  4.106   -22.970 1.000 18.943  0 215  GLY A N     1 ? 
ATOM   1622 C CA    . GLY A 1 216 ? 11.918  5.502   -22.565 1.000 19.434  0 215  GLY A CA    1 ? 
ATOM   1623 C C     . GLY A 1 216 ? 11.552  6.506   -23.659 1.000 17.332  0 215  GLY A C     1 ? 
ATOM   1624 O O     . GLY A 1 216 ? 11.732  7.701   -23.449 1.000 18.784  0 215  GLY A O     1 ? 
ATOM   1625 N N     . GLU A 1 217 ? 11.049  6.038   -24.797 1.000 17.351  0 216  GLU A N     1 ? 
ATOM   1626 C CA    . GLU A 1 217 ? 10.808  6.889   -25.956 1.000 18.000  0 216  GLU A CA    1 ? 
ATOM   1627 C C     . GLU A 1 217 ? 9.306   7.008   -26.226 1.000 16.419  0 216  GLU A C     1 ? 
ATOM   1628 O O     . GLU A 1 217 ? 8.561   6.040   -26.104 1.000 18.128  0 216  GLU A O     1 ? 
ATOM   1629 C CB    . GLU A 1 217 ? 11.476  6.270   -27.180 1.000 21.426  0 216  GLU A CB    1 ? 
ATOM   1630 C CG    . GLU A 1 217 ? 11.385  7.134   -28.427 1.000 22.613  0 216  GLU A CG    1 ? 
ATOM   1631 C CD    . GLU A 1 217 ? 12.157  6.607   -29.618 1.000 28.771  0 216  GLU A CD    1 ? 
ATOM   1632 O OE1   . GLU A 1 217 ? 12.963  5.671   -29.416 1.000 32.174  0 216  GLU A OE1   1 ? 
ATOM   1633 O OE2   . GLU A 1 217 ? 11.903  7.105   -30.728 1.000 29.599  0 216  GLU A OE2   1 ? 
ATOM   1634 N N     . ARG A 1 218 ? 8.861   8.181   -26.671 1.000 16.206  0 217  ARG A N     1 ? 
ATOM   1635 C CA    . ARG A 1 218 ? 7.482   8.351   -27.113 1.000 16.176  0 217  ARG A CA    1 ? 
ATOM   1636 C C     . ARG A 1 218 ? 7.169   7.512   -28.356 1.000 17.635  0 217  ARG A C     1 ? 
ATOM   1637 O O     . ARG A 1 218 ? 7.778   7.668   -29.403 1.000 20.206  0 217  ARG A O     1 ? 
ATOM   1638 C CB    . ARG A 1 218 ? 7.253   9.799   -27.547 1.000 16.972  0 217  ARG A CB    1 ? 
ATOM   1639 C CG    . ARG A 1 218 ? 5.838   10.140  -27.987 1.000 16.377  0 217  ARG A CG    1 ? 
ATOM   1640 C CD    . ARG A 1 218 ? 5.792   11.436  -28.766 1.000 16.574  0 217  ARG A CD    1 ? 
ATOM   1641 N NE    . ARG A 1 218 ? 5.917   12.579  -27.866 1.000 16.232  0 217  ARG A NE    1 ? 
ATOM   1642 C CZ    . ARG A 1 218 ? 4.926   13.136  -27.187 1.000 16.527  0 217  ARG A CZ    1 ? 
ATOM   1643 N NH1   . ARG A 1 218 ? 3.657   12.736  -27.346 1.000 16.537  0 217  ARG A NH1   1 ? 
ATOM   1644 N NH2   . ARG A 1 218 ? 5.233   14.127  -26.365 1.000 18.849  0 217  ARG A NH2   1 ? 
ATOM   1645 N N     . MET A 1 219 ? 6.120   6.709   -28.278 1.000 18.796  0 218  MET A N     1 ? 
ATOM   1646 C CA    . MET A 1 219 ? 5.712   5.893   -29.412 1.000 19.795  0 218  MET A CA    1 ? 
ATOM   1647 C C     . MET A 1 219 ? 4.363   6.425   -29.907 1.000 17.514  0 218  MET A C     1 ? 
ATOM   1648 O O     . MET A 1 219 ? 3.286   5.929   -29.559 1.000 18.382  0 218  MET A O     1 ? 
ATOM   1649 C CB    . MET A 1 219 ? 5.667   4.409   -29.026 1.000 20.980  0 218  MET A CB    1 ? 
ATOM   1650 C CG    . MET A 1 219 ? 7.023   3.838   -28.606 1.000 23.400  0 218  MET A CG    1 ? 
ATOM   1651 S SD    . MET A 1 219 ? 8.297   4.089   -29.855 1.000 29.070  0 218  MET A SD    1 ? 
ATOM   1652 C CE    . MET A 1 219 ? 7.778   2.794   -30.962 1.000 33.498  0 218  MET A CE    1 ? 
ATOM   1653 N N     . HIS A 1 220 ? 4.466   7.478   -30.722 1.000 16.692  0 219  HIS A N     1 ? 
ATOM   1654 C CA    . HIS A 1 220 ? 3.339   8.150   -31.316 1.000 16.718  0 219  HIS A CA    1 ? 
ATOM   1655 C C     . HIS A 1 220 ? 2.913   7.369   -32.546 1.000 18.189  0 219  HIS A C     1 ? 
ATOM   1656 O O     . HIS A 1 220 ? 3.461   6.314   -32.853 1.000 17.721  0 219  HIS A O     1 ? 
ATOM   1657 C CB    . HIS A 1 220 ? 3.706   9.602   -31.671 1.000 17.146  0 219  HIS A CB    1 ? 
ATOM   1658 C CG    . HIS A 1 220 ? 4.908   9.761   -32.531 1.000 15.952  0 219  HIS A CG    1 ? 
ATOM   1659 N ND1   . HIS A 1 220 ? 4.855   9.608   -33.899 1.000 17.256  0 219  HIS A ND1   1 ? 
ATOM   1660 C CD2   . HIS A 1 220 ? 6.191   10.078  -32.238 1.000 17.663  0 219  HIS A CD2   1 ? 
ATOM   1661 C CE1   . HIS A 1 220 ? 6.071   9.836   -34.402 1.000 18.471  0 219  HIS A CE1   1 ? 
ATOM   1662 N NE2   . HIS A 1 220 ? 6.906   10.136  -33.398 1.000 17.201  0 219  HIS A NE2   1 ? 
ATOM   1663 N N     . SER A 1 221 ? 1.850   7.860   -33.199 1.000 16.217  0 220  SER A N     1 ? 
ATOM   1664 C CA    . SER A 1 221 ? 1.247   7.090   -34.269 1.000 18.613  0 220  SER A CA    1 ? 
ATOM   1665 C C     . SER A 1 221 ? 2.203   6.954   -35.448 1.000 18.434  0 220  SER A C     1 ? 
ATOM   1666 O O     . SER A 1 221 ? 2.082   6.001   -36.216 1.000 18.876  0 220  SER A O     1 ? 
ATOM   1667 C CB    . SER A 1 221 ? -0.096  7.688   -34.682 1.000 18.482  0 220  SER A CB    1 ? 
ATOM   1668 O OG    . SER A 1 221 ? 0.122   8.819   -35.518 1.000 18.013  0 220  SER A OG    1 ? 
ATOM   1669 N N     . GLY A 1 222 ? 3.182   7.864   -35.570 1.000 16.872  0 221  GLY A N     1 ? 
ATOM   1670 C CA    . GLY A 1 222 ? 4.177   7.761   -36.626 1.000 18.737  0 221  GLY A CA    1 ? 
ATOM   1671 C C     . GLY A 1 222 ? 5.178   6.631   -36.396 1.000 18.905  0 221  GLY A C     1 ? 
ATOM   1672 O O     . GLY A 1 222 ? 5.677   6.058   -37.365 1.000 19.471  0 221  GLY A O     1 ? 
ATOM   1673 N N     . LYS A 1 223 ? 5.417   6.304   -35.116 1.000 16.420  0 222  LYS A N     1 ? 
ATOM   1674 C CA    . LYS A 1 223 ? 6.252   5.200   -34.710 1.000 18.891  0 222  LYS A CA    1 ? 
ATOM   1675 C C     . LYS A 1 223 ? 5.485   3.877   -34.744 1.000 19.306  0 222  LYS A C     1 ? 
ATOM   1676 O O     . LYS A 1 223 ? 6.049   2.894   -35.225 1.000 19.884  0 222  LYS A O     1 ? 
ATOM   1677 C CB    . LYS A 1 223 ? 6.784   5.386   -33.286 1.000 19.857  0 222  LYS A CB    1 ? 
ATOM   1678 C CG    . LYS A 1 223 ? 7.530   6.703   -33.043 1.000 20.768  0 222  LYS A CG    1 ? 
ATOM   1679 C CD    . LYS A 1 223 ? 8.816   6.828   -33.843 1.000 24.941  0 222  LYS A CD    1 ? 
ATOM   1680 C CE    . LYS A 1 223 ? 9.879   5.846   -33.429 1.000 27.915  0 222  LYS A CE    1 ? 
ATOM   1681 N NZ    . LYS A 1 223 ? 11.006  5.965   -34.354 1.000 30.442  0 222  LYS A NZ    1 ? 
ATOM   1682 N N     . ALA A 1 224 ? 4.269   3.842   -34.165 1.000 19.658  0 223  ALA A N     1 ? 
ATOM   1683 C CA    . ALA A 1 224 ? 3.473   2.623   -34.004 1.000 19.773  0 223  ALA A CA    1 ? 
ATOM   1684 C C     . ALA A 1 224 ? 2.911   2.132   -35.331 1.000 21.191  0 223  ALA A C     1 ? 
ATOM   1685 O O     . ALA A 1 224 ? 2.804   0.919   -35.545 1.000 21.022  0 223  ALA A O     1 ? 
ATOM   1686 C CB    . ALA A 1 224 ? 2.342   2.824   -33.039 1.000 20.163  0 223  ALA A CB    1 ? 
ATOM   1687 N N     . PHE A 1 225 ? 2.540   3.078   -36.208 1.000 19.497  0 224  PHE A N     1 ? 
ATOM   1688 C CA    . PHE A 1 225 ? 1.822   2.747   -37.416 1.000 18.322  0 224  PHE A CA    1 ? 
ATOM   1689 C C     . PHE A 1 225 ? 2.622   3.101   -38.668 1.000 18.262  0 224  PHE A C     1 ? 
ATOM   1690 O O     . PHE A 1 225 ? 2.816   2.246   -39.521 1.000 17.951  0 224  PHE A O     1 ? 
ATOM   1691 C CB    . PHE A 1 225 ? 0.432   3.414   -37.407 1.000 16.338  0 224  PHE A CB    1 ? 
ATOM   1692 C CG    . PHE A 1 225 ? -0.512  2.753   -36.412 1.000 17.814  0 224  PHE A CG    1 ? 
ATOM   1693 C CD1   . PHE A 1 225 ? -1.192  1.596   -36.738 1.000 18.339  0 224  PHE A CD1   1 ? 
ATOM   1694 C CD2   . PHE A 1 225 ? -0.619  3.234   -35.115 1.000 17.005  0 224  PHE A CD2   1 ? 
ATOM   1695 C CE1   . PHE A 1 225 ? -1.993  0.957   -35.830 1.000 19.296  0 224  PHE A CE1   1 ? 
ATOM   1696 C CE2   . PHE A 1 225 ? -1.453  2.616   -34.212 1.000 17.884  0 224  PHE A CE2   1 ? 
ATOM   1697 C CZ    . PHE A 1 225 ? -2.111  1.465   -34.557 1.000 18.039  0 224  PHE A CZ    1 ? 
ATOM   1698 N N     . LEU A 1 226 ? 3.011   4.366   -38.821 1.000 18.058  0 225  LEU A N     1 ? 
ATOM   1699 C CA    . LEU A 1 226 ? 3.474   4.834   -40.122 1.000 18.591  0 225  LEU A CA    1 ? 
ATOM   1700 C C     . LEU A 1 226 ? 4.864   4.298   -40.469 1.000 20.049  0 225  LEU A C     1 ? 
ATOM   1701 O O     . LEU A 1 226 ? 5.043   3.766   -41.574 1.000 19.115  0 225  LEU A O     1 ? 
ATOM   1702 C CB    . LEU A 1 226 ? 3.449   6.360   -40.181 1.000 18.796  0 225  LEU A CB    1 ? 
ATOM   1703 C CG    . LEU A 1 226 ? 3.621   6.924   -41.591 1.000 20.549  0 225  LEU A CG    1 ? 
ATOM   1704 C CD1   . LEU A 1 226 ? 2.473   6.498   -42.471 1.000 19.712  0 225  LEU A CD1   1 ? 
ATOM   1705 C CD2   . LEU A 1 226 ? 3.724   8.433   -41.509 1.000 22.152  0 225  LEU A CD2   1 ? 
ATOM   1706 N N     . GLU A 1 227 ? 5.848   4.462   -39.574 1.000 21.110  0 226  GLU A N     1 ? 
ATOM   1707 C CA    . GLU A 1 227 ? 7.223   4.080   -39.903 1.000 24.117  0 226  GLU A CA    1 ? 
ATOM   1708 C C     . GLU A 1 227 ? 7.299   2.628   -40.366 1.000 25.296  0 226  GLU A C     1 ? 
ATOM   1709 O O     . GLU A 1 227 ? 7.817   2.373   -41.447 1.000 23.093  0 226  GLU A O     1 ? 
ATOM   1710 C CB    . GLU A 1 227 ? 8.263   4.216   -38.796 1.000 28.465  0 226  GLU A CB    1 ? 
ATOM   1711 C CG    . GLU A 1 227 ? 8.725   5.660   -38.662 1.000 34.531  0 226  GLU A CG    1 ? 
ATOM   1712 C CD    . GLU A 1 227 ? 9.782   5.888   -37.601 1.000 40.447  0 226  GLU A CD    1 ? 
ATOM   1713 O OE1   . GLU A 1 227 ? 10.173  4.929   -36.877 1.000 40.021  0 226  GLU A OE1   1 ? 
ATOM   1714 O OE2   . GLU A 1 227 ? 10.157  7.073   -37.479 1.000 37.374  0 226  GLU A OE2   1 ? 
ATOM   1715 N N     . PRO A 1 228 ? 6.738   1.638   -39.645 1.000 25.049  0 227  PRO A N     1 ? 
ATOM   1716 C CA    . PRO A 1 228 ? 6.734   0.260   -40.147 1.000 28.070  0 227  PRO A CA    1 ? 
ATOM   1717 C C     . PRO A 1 228 ? 6.103   0.094   -41.523 1.000 25.459  0 227  PRO A C     1 ? 
ATOM   1718 O O     . PRO A 1 228 ? 6.563   -0.712  -42.312 1.000 28.293  0 227  PRO A O     1 ? 
ATOM   1719 C CB    . PRO A 1 228 ? 5.965   -0.552  -39.093 1.000 27.682  0 227  PRO A CB    1 ? 
ATOM   1720 C CG    . PRO A 1 228 ? 5.907   0.337   -37.891 1.000 29.002  0 227  PRO A CG    1 ? 
ATOM   1721 C CD    . PRO A 1 228 ? 6.097   1.763   -38.329 1.000 25.109  0 227  PRO A CD    1 ? 
ATOM   1722 N N     . ALA A 1 229 ? 5.073   0.882   -41.835 1.000 22.083  0 228  ALA A N     1 ? 
ATOM   1723 C CA    . ALA A 1 229 ? 4.352   0.718   -43.088 1.000 21.322  0 228  ALA A CA    1 ? 
ATOM   1724 C C     . ALA A 1 229 ? 5.080   1.370   -44.259 1.000 23.878  0 228  ALA A C     1 ? 
ATOM   1725 O O     . ALA A 1 229 ? 4.791   1.055   -45.409 1.000 20.340  0 228  ALA A O     1 ? 
ATOM   1726 C CB    . ALA A 1 229 ? 2.956   1.287   -42.986 1.000 23.214  0 228  ALA A CB    1 ? 
ATOM   1727 N N     . MET A 1 230 ? 6.035   2.255   -43.970 1.000 23.550  0 229  MET A N     1 ? 
ATOM   1728 C CA    . MET A 1 230 ? 6.731   2.989   -45.012 1.000 26.017  0 229  MET A CA    1 ? 
ATOM   1729 C C     . MET A 1 230 ? 7.703   2.141   -45.839 1.000 26.328  0 229  MET A C     1 ? 
ATOM   1730 O O     . MET A 1 230 ? 8.105   2.589   -46.897 1.000 26.570  0 229  MET A O     1 ? 
ATOM   1731 C CB    . MET A 1 230 ? 7.390   4.234   -44.410 1.000 24.654  0 229  MET A CB    1 ? 
ATOM   1732 C CG    . MET A 1 230 ? 6.359   5.371   -44.373 1.000 25.772  0 229  MET A CG    1 ? 
ATOM   1733 S SD    . MET A 1 230 ? 6.943   6.865   -43.558 1.000 30.342  0 229  MET A SD    1 ? 
ATOM   1734 C CE    . MET A 1 230 ? 7.913   7.414   -44.983 1.000 30.692  0 229  MET A CE    1 ? 
ATOM   1735 N N     . SER A 1 231 ? 8.009   0.905   -45.457 1.000 26.737  0 230  SER A N     1 ? 
ATOM   1736 C CA    . SER A 1 231 ? 8.766   0.056   -46.375 1.000 32.335  0 230  SER A CA    1 ? 
ATOM   1737 C C     . SER A 1 231 ? 7.860   -0.565  -47.443 1.000 29.317  0 230  SER A C     1 ? 
ATOM   1738 O O     . SER A 1 231 ? 8.324   -1.275  -48.343 1.000 31.551  0 230  SER A O     1 ? 
ATOM   1739 C CB    . SER A 1 231 ? 9.533   -1.002  -45.646 1.000 37.313  0 230  SER A CB    1 ? 
ATOM   1740 O OG    . SER A 1 231 ? 8.857   -1.368  -44.460 1.000 40.904  0 230  SER A OG    1 ? 
ATOM   1741 N N     . ARG A 1 232 ? 6.554   -0.306  -47.385 1.000 23.867  0 231  ARG A N     1 ? 
ATOM   1742 C CA    . ARG A 1 232 ? 5.663   -0.901  -48.370 1.000 22.100  0 231  ARG A CA    1 ? 
ATOM   1743 C C     . ARG A 1 232 ? 5.714   -0.100  -49.656 1.000 23.288  0 231  ARG A C     1 ? 
ATOM   1744 O O     . ARG A 1 232 ? 5.643   1.129   -49.620 1.000 23.779  0 231  ARG A O     1 ? 
ATOM   1745 C CB    . ARG A 1 232 ? 4.222   -0.940  -47.857 1.000 22.412  0 231  ARG A CB    1 ? 
ATOM   1746 C CG    . ARG A 1 232 ? 4.117   -1.820  -46.618 1.000 22.021  0 231  ARG A CG    1 ? 
ATOM   1747 C CD    . ARG A 1 232 ? 2.747   -1.680  -45.974 1.000 19.279  0 231  ARG A CD    1 ? 
ATOM   1748 N NE    . ARG A 1 232 ? 2.839   -2.295  -44.657 1.000 19.565  0 231  ARG A NE    1 ? 
ATOM   1749 C CZ    . ARG A 1 232 ? 1.964   -2.169  -43.676 1.000 21.451  0 231  ARG A CZ    1 ? 
ATOM   1750 N NH1   . ARG A 1 232 ? 0.921   -1.369  -43.789 1.000 19.827  0 231  ARG A NH1   1 ? 
ATOM   1751 N NH2   . ARG A 1 232 ? 2.135   -2.871  -42.571 1.000 21.358  0 231  ARG A NH2   1 ? 
ATOM   1752 N N     . PRO A 1 233 ? 5.706   -0.747  -50.834 1.000 23.665  0 232  PRO A N     1 ? 
ATOM   1753 C CA    . PRO A 1 233 ? 5.749   -0.009  -52.095 1.000 26.719  0 232  PRO A CA    1 ? 
ATOM   1754 C C     . PRO A 1 233 ? 4.472   0.756   -52.419 1.000 24.207  0 232  PRO A C     1 ? 
ATOM   1755 O O     . PRO A 1 233 ? 4.495   1.631   -53.287 1.000 22.393  0 232  PRO A O     1 ? 
ATOM   1756 C CB    . PRO A 1 233 ? 5.983   -1.110  -53.128 1.000 26.539  0 232  PRO A CB    1 ? 
ATOM   1757 C CG    . PRO A 1 233 ? 5.312   -2.313  -52.502 1.000 29.028  0 232  PRO A CG    1 ? 
ATOM   1758 C CD    . PRO A 1 233 ? 5.741   -2.205  -51.034 1.000 26.486  0 232  PRO A CD    1 ? 
ATOM   1759 N N     . ASN A 1 234 ? 3.375   0.358   -51.776 1.000 21.551  0 233  ASN A N     1 ? 
ATOM   1760 C CA    . ASN A 1 234 ? 2.037   0.834   -52.080 1.000 18.974  0 233  ASN A CA    1 ? 
ATOM   1761 C C     . ASN A 1 234 ? 1.650   2.009   -51.170 1.000 19.692  0 233  ASN A C     1 ? 
ATOM   1762 O O     . ASN A 1 234 ? 0.614   2.616   -51.383 1.000 20.823  0 233  ASN A O     1 ? 
ATOM   1763 C CB    . ASN A 1 234 ? 1.047   -0.321  -52.072 1.000 19.003  0 233  ASN A CB    1 ? 
ATOM   1764 C CG    . ASN A 1 234 ? 1.064   -1.076  -50.764 1.000 19.302  0 233  ASN A CG    1 ? 
ATOM   1765 O OD1   . ASN A 1 234 ? 2.128   -1.565  -50.354 1.000 20.654  0 233  ASN A OD1   1 ? 
ATOM   1766 N ND2   . ASN A 1 234 ? -0.086  -1.217  -50.121 1.000 19.204  0 233  ASN A ND2   1 ? 
ATOM   1767 N N     . LEU A 1 235 ? 2.523   2.410   -50.242 1.000 18.754  0 234  LEU A N     1 ? 
ATOM   1768 C CA    . LEU A 1 235 ? 2.300   3.597   -49.406 1.000 17.849  0 234  LEU A CA    1 ? 
ATOM   1769 C C     . LEU A 1 235 ? 3.258   4.694   -49.836 1.000 20.442  0 234  LEU A C     1 ? 
ATOM   1770 O O     . LEU A 1 235 ? 4.488   4.475   -49.951 1.000 22.775  0 234  LEU A O     1 ? 
ATOM   1771 C CB    . LEU A 1 235 ? 2.530   3.249   -47.929 1.000 17.858  0 234  LEU A CB    1 ? 
ATOM   1772 C CG    . LEU A 1 235 ? 2.369   4.390   -46.911 1.000 19.588  0 234  LEU A CG    1 ? 
ATOM   1773 C CD1   . LEU A 1 235 ? 0.994   5.003   -46.954 1.000 21.254  0 234  LEU A CD1   1 ? 
ATOM   1774 C CD2   . LEU A 1 235 ? 2.678   3.885   -45.511 1.000 21.066  0 234  LEU A CD2   1 ? 
ATOM   1775 N N     . HIS A 1 236 ? 2.680   5.879   -50.049 1.000 19.311  0 235  HIS A N     1 ? 
ATOM   1776 C CA    . HIS A 1 236 ? 3.428   7.078   -50.344 1.000 19.908  0 235  HIS A CA    1 ? 
ATOM   1777 C C     . HIS A 1 236 ? 2.989   8.202   -49.409 1.000 19.421  0 235  HIS A C     1 ? 
ATOM   1778 O O     . HIS A 1 236 ? 1.794   8.420   -49.202 1.000 19.856  0 235  HIS A O     1 ? 
ATOM   1779 C CB    . HIS A 1 236 ? 3.172   7.424   -51.812 1.000 23.553  0 235  HIS A CB    1 ? 
ATOM   1780 C CG    . HIS A 1 236 ? 3.404   6.246   -52.679 1.000 27.830  0 235  HIS A CG    1 ? 
ATOM   1781 N ND1   . HIS A 1 236 ? 4.694   5.849   -52.928 1.000 30.563  0 235  HIS A ND1   1 ? 
ATOM   1782 C CD2   . HIS A 1 236 ? 2.592   5.320   -53.239 1.000 31.692  0 235  HIS A CD2   1 ? 
ATOM   1783 C CE1   . HIS A 1 236 ? 4.665   4.768   -53.705 1.000 33.160  0 235  HIS A CE1   1 ? 
ATOM   1784 N NE2   . HIS A 1 236 ? 3.403   4.429   -53.916 1.000 33.009  0 235  HIS A NE2   1 ? 
ATOM   1785 N N     . VAL A 1 237 ? 3.966   8.911   -48.853 1.000 20.102  0 236  VAL A N     1 ? 
ATOM   1786 C CA    . VAL A 1 237 ? 3.697   9.938   -47.861 1.000 19.476  0 236  VAL A CA    1 ? 
ATOM   1787 C C     . VAL A 1 237 ? 4.284   11.268  -48.326 1.000 18.761  0 236  VAL A C     1 ? 
ATOM   1788 O O     . VAL A 1 237 ? 5.497   11.359  -48.508 1.000 20.037  0 236  VAL A O     1 ? 
ATOM   1789 C CB    . VAL A 1 237 ? 4.246   9.587   -46.471 1.000 19.536  0 236  VAL A CB    1 ? 
ATOM   1790 C CG1   . VAL A 1 237 ? 3.838   10.621  -45.431 1.000 20.053  0 236  VAL A CG1   1 ? 
ATOM   1791 C CG2   . VAL A 1 237 ? 3.824   8.192   -46.004 1.000 19.466  0 236  VAL A CG2   1 ? 
ATOM   1792 N N     . LEU A 1 238 ? 3.409   12.268  -48.476 1.000 18.005  0 237  LEU A N     1 ? 
ATOM   1793 C CA    . LEU A 1 238 ? 3.811   13.616  -48.840 1.000 17.181  0 237  LEU A CA    1 ? 
ATOM   1794 C C     . LEU A 1 238 ? 3.670   14.517  -47.620 1.000 17.788  0 237  LEU A C     1 ? 
ATOM   1795 O O     . LEU A 1 238 ? 2.561   14.706  -47.149 1.000 20.210  0 237  LEU A O     1 ? 
ATOM   1796 C CB    . LEU A 1 238 ? 2.913   14.076  -49.986 1.000 17.816  0 237  LEU A CB    1 ? 
ATOM   1797 C CG    . LEU A 1 238 ? 3.095   15.518  -50.462 1.000 18.878  0 237  LEU A CG    1 ? 
ATOM   1798 C CD1   . LEU A 1 238 ? 4.455   15.754  -51.071 1.000 20.440  0 237  LEU A CD1   1 ? 
ATOM   1799 C CD2   . LEU A 1 238 ? 2.018   15.891  -51.448 1.000 20.958  0 237  LEU A CD2   1 ? 
ATOM   1800 N N     . ILE A 1 239 ? 4.774   15.099  -47.140 1.000 18.847  0 238  ILE A N     1 ? 
ATOM   1801 C CA    . ILE A 1 239 ? 4.707   16.019  -46.013 1.000 19.093  0 238  ILE A CA    1 ? 
ATOM   1802 C C     . ILE A 1 239 ? 4.888   17.461  -46.476 1.000 20.102  0 238  ILE A C     1 ? 
ATOM   1803 O O     . ILE A 1 239 ? 5.085   17.721  -47.653 1.000 20.049  0 238  ILE A O     1 ? 
ATOM   1804 C CB    . ILE A 1 239 ? 5.723   15.658  -44.927 1.000 19.403  0 238  ILE A CB    1 ? 
ATOM   1805 C CG1   . ILE A 1 239 ? 7.166   15.851  -45.416 1.000 21.125  0 238  ILE A CG1   1 ? 
ATOM   1806 C CG2   . ILE A 1 239 ? 5.431   14.238  -44.439 1.000 18.664  0 238  ILE A CG2   1 ? 
ATOM   1807 C CD1   . ILE A 1 239 ? 8.183   15.723  -44.300 1.000 22.829  0 238  ILE A CD1   1 ? 
ATOM   1808 N N     . GLU A 1 240 ? 4.742   18.408  -45.537 1.000 18.874  0 239  GLU A N     1 ? 
ATOM   1809 C CA    . GLU A 1 240 ? 4.940   19.822  -45.846 1.000 20.516  0 239  GLU A CA    1 ? 
ATOM   1810 C C     . GLU A 1 240 ? 3.967   20.383  -46.883 1.000 21.344  0 239  GLU A C     1 ? 
ATOM   1811 O O     . GLU A 1 240 ? 4.265   21.403  -47.507 1.000 21.091  0 239  GLU A O     1 ? 
ATOM   1812 C CB    . GLU A 1 240 ? 6.397   20.048  -46.268 1.000 22.726  0 239  GLU A CB    1 ? 
ATOM   1813 C CG    . GLU A 1 240 ? 7.359   19.815  -45.119 1.000 24.278  0 239  GLU A CG    1 ? 
ATOM   1814 C CD    . GLU A 1 240 ? 8.838   20.050  -45.409 1.000 27.507  0 239  GLU A CD    1 ? 
ATOM   1815 O OE1   . GLU A 1 240 ? 9.199   20.519  -46.538 1.000 30.547  0 239  GLU A OE1   1 ? 
ATOM   1816 O OE2   . GLU A 1 240 ? 9.626   19.689  -44.495 1.000 28.812  0 239  GLU A OE2   1 ? 
ATOM   1817 N N     . ASN A 1 241 ? 2.801   19.742  -47.053 1.000 19.175  0 240  ASN A N     1 ? 
ATOM   1818 C CA    . ASN A 1 241 ? 1.788   20.170  -48.001 1.000 19.970  0 240  ASN A CA    1 ? 
ATOM   1819 C C     . ASN A 1 241 ? 0.423   20.204  -47.318 1.000 20.738  0 240  ASN A C     1 ? 
ATOM   1820 O O     . ASN A 1 241 ? -0.003  19.216  -46.712 1.000 20.440  0 240  ASN A O     1 ? 
ATOM   1821 C CB    . ASN A 1 241 ? 1.735   19.250  -49.221 1.000 21.742  0 240  ASN A CB    1 ? 
ATOM   1822 C CG    . ASN A 1 241 ? 2.850   19.522  -50.191 1.000 20.658  0 240  ASN A CG    1 ? 
ATOM   1823 O OD1   . ASN A 1 241 ? 2.624   20.244  -51.168 1.000 22.439  0 240  ASN A OD1   1 ? 
ATOM   1824 N ND2   . ASN A 1 241 ? 4.053   19.042  -49.911 1.000 20.248  0 240  ASN A ND2   1 ? 
ATOM   1825 N N     . THR A 1 242 ? -0.274  21.336  -47.462 1.000 20.122  0 241  THR A N     1 ? 
ATOM   1826 C CA    . THR A 1 242 ? -1.592  21.555  -46.885 1.000 20.797  0 241  THR A CA    1 ? 
ATOM   1827 C C     . THR A 1 242 ? -2.655  21.319  -47.944 1.000 20.546  0 241  THR A C     1 ? 
ATOM   1828 O O     . THR A 1 242 ? -2.570  21.906  -49.017 1.000 20.289  0 241  THR A O     1 ? 
ATOM   1829 C CB    . THR A 1 242 ? -1.665  23.004  -46.409 1.000 23.252  0 241  THR A CB    1 ? 
ATOM   1830 O OG1   . THR A 1 242 ? -0.707  23.210  -45.379 1.000 22.892  0 241  THR A OG1   1 ? 
ATOM   1831 C CG2   . THR A 1 242 ? -3.034  23.407  -45.889 1.000 22.447  0 241  THR A CG2   1 ? 
ATOM   1832 N N     . VAL A 1 243 ? -3.654  20.495  -47.629 1.000 20.324  0 242  VAL A N     1 ? 
ATOM   1833 C CA    . VAL A 1 243 ? -4.820  20.349  -48.482 1.000 20.126  0 242  VAL A CA    1 ? 
ATOM   1834 C C     . VAL A 1 243 ? -5.656  21.624  -48.398 1.000 22.475  0 242  VAL A C     1 ? 
ATOM   1835 O O     . VAL A 1 243 ? -6.040  22.048  -47.310 1.000 22.367  0 242  VAL A O     1 ? 
ATOM   1836 C CB    . VAL A 1 243 ? -5.601  19.072  -48.100 1.000 18.591  0 242  VAL A CB    1 ? 
ATOM   1837 C CG1   . VAL A 1 243 ? -6.953  18.977  -48.781 1.000 19.776  0 242  VAL A CG1   1 ? 
ATOM   1838 C CG2   . VAL A 1 243 ? -4.739  17.859  -48.409 1.000 18.386  0 242  VAL A CG2   1 ? 
ATOM   1839 N N     . THR A 1 244 ? -5.903  22.249  -49.566 1.000 20.126  0 243  THR A N     1 ? 
ATOM   1840 C CA    . THR A 1 244 ? -6.601  23.516  -49.635 1.000 20.186  0 243  THR A CA    1 ? 
ATOM   1841 C C     . THR A 1 244 ? -8.102  23.312  -49.789 1.000 21.275  0 243  THR A C     1 ? 
ATOM   1842 O O     . THR A 1 244 ? -8.877  24.140  -49.331 1.000 24.697  0 243  THR A O     1 ? 
ATOM   1843 C CB    . THR A 1 244 ? -5.972  24.329  -50.762 1.000 21.877  0 243  THR A CB    1 ? 
ATOM   1844 O OG1   . THR A 1 244 ? -5.975  23.535  -51.954 1.000 22.452  0 243  THR A OG1   1 ? 
ATOM   1845 C CG2   . THR A 1 244 ? -4.548  24.697  -50.406 1.000 21.935  0 243  THR A CG2   1 ? 
ATOM   1846 N N     . ARG A 1 245 ? -8.508  22.250  -50.494 1.000 20.291  0 244  ARG A N     1 ? 
ATOM   1847 C CA    . ARG A 1 245 ? -9.907  21.922  -50.666 1.000 20.775  0 244  ARG A CA    1 ? 
ATOM   1848 C C     . ARG A 1 245 ? -9.976  20.611  -51.442 1.000 19.723  0 244  ARG A C     1 ? 
ATOM   1849 O O     . ARG A 1 245 ? -8.968  20.161  -51.974 1.000 20.983  0 244  ARG A O     1 ? 
ATOM   1850 C CB    . ARG A 1 245 ? -10.662 23.010  -51.441 1.000 23.843  0 244  ARG A CB    1 ? 
ATOM   1851 C CG    . ARG A 1 245 ? -10.118 23.195  -52.837 1.000 27.059  0 244  ARG A CG    1 ? 
ATOM   1852 C CD    . ARG A 1 245 ? -10.918 24.206  -53.666 1.000 35.233  0 244  ARG A CD    1 ? 
ATOM   1853 N NE    . ARG A 1 245 ? -10.102 24.614  -54.817 1.000 40.923  0 244  ARG A NE    1 ? 
ATOM   1854 C CZ    . ARG A 1 245 ? -10.458 24.585  -56.103 1.000 46.614  0 244  ARG A CZ    1 ? 
ATOM   1855 N NH1   . ARG A 1 245 ? -11.696 24.268  -56.456 1.000 44.757  0 244  ARG A NH1   1 ? 
ATOM   1856 N NH2   . ARG A 1 245 ? -9.560  24.883  -57.032 1.000 47.210  0 244  ARG A NH2   1 ? 
ATOM   1857 N N     . LEU A 1 246 ? -11.179 20.049  -51.473 1.000 17.963  0 245  LEU A N     1 ? 
ATOM   1858 C CA    . LEU A 1 246 ? -11.524 18.912  -52.305 1.000 19.967  0 245  LEU A CA    1 ? 
ATOM   1859 C C     . LEU A 1 246 ? -12.237 19.483  -53.515 1.000 22.172  0 245  LEU A C     1 ? 
ATOM   1860 O O     . LEU A 1 246 ? -12.917 20.497  -53.396 1.000 23.473  0 245  LEU A O     1 ? 
ATOM   1861 C CB    . LEU A 1 246 ? -12.446 17.952  -51.574 1.000 20.985  0 245  LEU A CB    1 ? 
ATOM   1862 C CG    . LEU A 1 246 ? -11.947 17.464  -50.208 1.000 23.158  0 245  LEU A CG    1 ? 
ATOM   1863 C CD1   . LEU A 1 246 ? -12.961 16.495  -49.669 1.000 27.212  0 245  LEU A CD1   1 ? 
ATOM   1864 C CD2   . LEU A 1 246 ? -10.568 16.827  -50.316 1.000 21.747  0 245  LEU A CD2   1 ? 
ATOM   1865 N N     . ILE A 1 247 ? -11.998 18.860  -54.655 1.000 24.630  0 246  ILE A N     1 ? 
ATOM   1866 C CA    . ILE A 1 247 ? -12.566 19.291  -55.912 1.000 25.836  0 246  ILE A CA    1 ? 
ATOM   1867 C C     . ILE A 1 247 ? -13.578 18.239  -56.351 1.000 25.862  0 246  ILE A C     1 ? 
ATOM   1868 O O     . ILE A 1 247 ? -13.332 17.048  -56.282 1.000 27.108  0 246  ILE A O     1 ? 
ATOM   1869 C CB    . ILE A 1 247 ? -11.450 19.525  -56.937 1.000 27.776  0 246  ILE A CB    1 ? 
ATOM   1870 C CG1   . ILE A 1 247 ? -10.584 20.683  -56.484 1.000 28.483  0 246  ILE A CG1   1 ? 
ATOM   1871 C CG2   . ILE A 1 247 ? -12.039 19.749  -58.336 1.000 29.967  0 246  ILE A CG2   1 ? 
ATOM   1872 C CD1   . ILE A 1 247 ? -9.457  21.006  -57.432 1.000 32.942  0 246  ILE A CD1   1 ? 
ATOM   1873 N N     . GLN A 1 248 ? -14.757 18.720  -56.736 1.000 26.113  0 247  GLN A N     1 ? 
ATOM   1874 C CA    . GLN A 1 248 ? -15.876 17.872  -57.060 1.000 25.698  0 247  GLN A CA    1 ? 
ATOM   1875 C C     . GLN A 1 248 ? -15.559 17.109  -58.338 1.000 27.063  0 247  GLN A C     1 ? 
ATOM   1876 O O     . GLN A 1 248 ? -15.037 17.677  -59.291 1.000 26.507  0 247  GLN A O     1 ? 
ATOM   1877 C CB    . GLN A 1 248 ? -17.131 18.731  -57.235 1.000 26.614  0 247  GLN A CB    1 ? 
ATOM   1878 C CG    . GLN A 1 248 ? -18.413 17.927  -57.209 1.000 29.995  0 247  GLN A CG    1 ? 
ATOM   1879 C CD    . GLN A 1 248 ? -19.673 18.755  -57.356 1.000 32.264  0 247  GLN A CD    1 ? 
ATOM   1880 O OE1   . GLN A 1 248 ? -19.756 19.951  -57.037 1.000 33.574  0 247  GLN A OE1   1 ? 
ATOM   1881 N NE2   . GLN A 1 248 ? -20.706 18.054  -57.768 1.000 32.968  0 247  GLN A NE2   1 ? 
ATOM   1882 N N     . THR A 1 249 ? -15.914 15.827  -58.346 1.000 27.254  0 248  THR A N     1 ? 
ATOM   1883 C CA    . THR A 1 249 ? -15.717 14.965  -59.502 1.000 27.734  0 248  THR A CA    1 ? 
ATOM   1884 C C     . THR A 1 249 ? -17.086 14.394  -59.884 1.000 29.486  0 248  THR A C     1 ? 
ATOM   1885 O O     . THR A 1 249 ? -18.096 14.910  -59.423 1.000 30.740  0 248  THR A O     1 ? 
ATOM   1886 C CB    . THR A 1 249 ? -14.673 13.909  -59.124 1.000 27.607  0 248  THR A CB    1 ? 
ATOM   1887 O OG1   . THR A 1 249 ? -15.004 13.312  -57.872 1.000 26.118  0 248  THR A OG1   1 ? 
ATOM   1888 C CG2   . THR A 1 249 ? -13.279 14.507  -59.026 1.000 28.367  0 248  THR A CG2   1 ? 
ATOM   1889 N N     . LYS A 1 250 ? -17.118 13.320  -60.685 1.000 35.385  0 249  LYS A N     1 ? 
ATOM   1890 C CA    . LYS A 1 250 ? -18.357 12.784  -61.242 1.000 37.542  0 249  LYS A CA    1 ? 
ATOM   1891 C C     . LYS A 1 250 ? -19.304 12.272  -60.161 1.000 36.036  0 249  LYS A C     1 ? 
ATOM   1892 O O     . LYS A 1 250 ? -18.882 11.770  -59.124 1.000 35.777  0 249  LYS A O     1 ? 
ATOM   1893 C CB    . LYS A 1 250 ? -18.025 11.619  -62.177 1.000 48.636  0 249  LYS A CB    1 ? 
ATOM   1894 C CG    . LYS A 1 250 ? -17.024 11.945  -63.277 1.000 62.164  0 249  LYS A CG    1 ? 
ATOM   1895 C CD    . LYS A 1 250 ? -17.230 13.300  -63.956 1.000 75.242  0 249  LYS A CD    1 ? 
ATOM   1896 C CE    . LYS A 1 250 ? -16.174 13.633  -64.977 1.000 83.613  0 249  LYS A CE    1 ? 
ATOM   1897 N NZ    . LYS A 1 250 ? -16.124 12.666  -66.079 1.000 86.758  0 249  LYS A NZ    1 ? 
ATOM   1898 N N     . THR A 1 251 ? -20.609 12.383  -60.417 1.000 31.099  0 250  THR A N     1 ? 
ATOM   1899 C CA    . THR A 1 251 ? -21.621 11.798  -59.557 1.000 29.905  0 250  THR A CA    1 ? 
ATOM   1900 C C     . THR A 1 251 ? -21.434 10.282  -59.480 1.000 31.300  0 250  THR A C     1 ? 
ATOM   1901 O O     . THR A 1 251 ? -21.157 9.608   -60.479 1.000 27.586  0 250  THR A O     1 ? 
ATOM   1902 C CB    . THR A 1 251 ? -22.997 12.118  -60.127 1.000 30.471  0 250  THR A CB    1 ? 
ATOM   1903 O OG1   . THR A 1 251 ? -23.093 13.538  -60.151 1.000 31.475  0 250  THR A OG1   1 ? 
ATOM   1904 C CG2   . THR A 1 251 ? -24.126 11.489  -59.338 1.000 31.561  0 250  THR A CG2   1 ? 
ATOM   1905 N N     . THR A 1 252 ? -21.650 9.750   -58.285 1.000 30.264  0 251  THR A N     1 ? 
ATOM   1906 C CA    . THR A 1 252 ? -21.510 8.325   -58.032 1.000 33.712  0 251  THR A CA    1 ? 
ATOM   1907 C C     . THR A 1 252 ? -22.683 7.945   -57.144 1.000 35.118  0 251  THR A C     1 ? 
ATOM   1908 O O     . THR A 1 252 ? -22.924 8.569   -56.109 1.000 32.997  0 251  THR A O     1 ? 
ATOM   1909 C CB    . THR A 1 252 ? -20.159 8.034   -57.373 1.000 39.402  0 251  THR A CB    1 ? 
ATOM   1910 O OG1   . THR A 1 252 ? -19.169 8.659   -58.189 1.000 39.930  0 251  THR A OG1   1 ? 
ATOM   1911 C CG2   . THR A 1 252 ? -19.865 6.553   -57.238 1.000 40.730  0 251  THR A CG2   1 ? 
ATOM   1912 N N     . ASN A 1 253 ? -23.487 7.007   -57.635 1.000 38.771  0 252  ASN A N     1 ? 
ATOM   1913 C CA    . ASN A 1 253 ? -24.633 6.525   -56.895 1.000 40.625  0 252  ASN A CA    1 ? 
ATOM   1914 C C     . ASN A 1 253 ? -25.587 7.682   -56.618 1.000 39.661  0 252  ASN A C     1 ? 
ATOM   1915 O O     . ASN A 1 253 ? -26.175 7.758   -55.552 1.000 36.863  0 252  ASN A O     1 ? 
ATOM   1916 C CB    . ASN A 1 253 ? -24.161 5.776   -55.653 1.000 47.755  0 252  ASN A CB    1 ? 
ATOM   1917 C CG    . ASN A 1 253 ? -25.205 4.819   -55.124 1.000 57.496  0 252  ASN A CG    1 ? 
ATOM   1918 O OD1   . ASN A 1 253 ? -25.881 4.142   -55.910 1.000 58.864  0 252  ASN A OD1   1 ? 
ATOM   1919 N ND2   . ASN A 1 253 ? -25.365 4.759   -53.808 1.000 59.823  0 252  ASN A ND2   1 ? 
ATOM   1920 N N     . GLY A 1 254 ? -25.731 8.591   -57.588 1.000 34.507  0 253  GLY A N     1 ? 
ATOM   1921 C CA    . GLY A 1 254 ? -26.664 9.693   -57.448 1.000 36.449  0 253  GLY A CA    1 ? 
ATOM   1922 C C     . GLY A 1 254 ? -26.213 10.767  -56.454 1.000 37.383  0 253  GLY A C     1 ? 
ATOM   1923 O O     . GLY A 1 254 ? -26.994 11.661  -56.163 1.000 34.453  0 253  GLY A O     1 ? 
ATOM   1924 N N     . LEU A 1 255 ? -24.969 10.716  -55.939 1.000 28.051  0 254  LEU A N     1 ? 
ATOM   1925 C CA    . LEU A 1 255 ? -24.506 11.767  -55.040 1.000 29.710  0 254  LEU A CA    1 ? 
ATOM   1926 C C     . LEU A 1 255 ? -23.247 12.395  -55.603 1.000 26.843  0 254  LEU A C     1 ? 
ATOM   1927 O O     . LEU A 1 255 ? -22.427 11.709  -56.196 1.000 26.564  0 254  LEU A O     1 ? 
ATOM   1928 C CB    . LEU A 1 255 ? -24.208 11.262  -53.629 1.000 29.229  0 254  LEU A CB    1 ? 
ATOM   1929 C CG    . LEU A 1 255 ? -25.354 10.610  -52.862 1.000 30.903  0 254  LEU A CG    1 ? 
ATOM   1930 C CD1   . LEU A 1 255 ? -24.686 9.993   -51.633 1.000 33.991  0 254  LEU A CD1   1 ? 
ATOM   1931 C CD2   . LEU A 1 255 ? -26.448 11.583  -52.464 1.000 31.763  0 254  LEU A CD2   1 ? 
ATOM   1932 N N     . PRO A 1 256 ? -22.996 13.690  -55.310 1.000 24.632  0 255  PRO A N     1 ? 
ATOM   1933 C CA    . PRO A 1 256 ? -21.753 14.335  -55.715 1.000 24.285  0 255  PRO A CA    1 ? 
ATOM   1934 C C     . PRO A 1 256 ? -20.581 13.665  -55.011 1.000 25.077  0 255  PRO A C     1 ? 
ATOM   1935 O O     . PRO A 1 256 ? -20.731 13.192  -53.887 1.000 25.478  0 255  PRO A O     1 ? 
ATOM   1936 C CB    . PRO A 1 256 ? -21.941 15.785  -55.253 1.000 24.835  0 255  PRO A CB    1 ? 
ATOM   1937 C CG    . PRO A 1 256 ? -22.837 15.649  -54.083 1.000 27.350  0 255  PRO A CG    1 ? 
ATOM   1938 C CD    . PRO A 1 256 ? -23.835 14.553  -54.465 1.000 23.628  0 255  PRO A CD    1 ? 
ATOM   1939 N N     . SER A 1 257 ? -19.444 13.607  -55.704 1.000 23.694  0 256  SER A N     1 ? 
ATOM   1940 C CA    . SER A 1 257 ? -18.238 13.037  -55.140 1.000 24.947  0 256  SER A CA    1 ? 
ATOM   1941 C C     . SER A 1 257 ? -17.153 14.098  -55.237 1.000 24.860  0 256  SER A C     1 ? 
ATOM   1942 O O     . SER A 1 257 ? -17.233 14.996  -56.065 1.000 23.486  0 256  SER A O     1 ? 
ATOM   1943 C CB    . SER A 1 257 ? -17.863 11.745  -55.806 1.000 28.101  0 256  SER A CB    1 ? 
ATOM   1944 O OG    . SER A 1 257 ? -17.277 11.956  -57.078 1.000 28.722  0 256  SER A OG    1 ? 
ATOM   1945 N N     . PHE A 1 258 ? -16.142 13.962  -54.383 1.000 22.525  0 257  PHE A N     1 ? 
ATOM   1946 C CA    . PHE A 1 258 ? -15.036 14.884  -54.283 1.000 23.173  0 257  PHE A CA    1 ? 
ATOM   1947 C C     . PHE A 1 258 ? -13.735 14.101  -54.252 1.000 26.399  0 257  PHE A C     1 ? 
ATOM   1948 O O     . PHE A 1 258 ? -13.082 14.041  -53.204 1.000 25.050  0 257  PHE A O     1 ? 
ATOM   1949 C CB    . PHE A 1 258 ? -15.241 15.653  -52.978 1.000 23.669  0 257  PHE A CB    1 ? 
ATOM   1950 C CG    . PHE A 1 258 ? -16.417 16.617  -53.027 1.000 22.781  0 257  PHE A CG    1 ? 
ATOM   1951 C CD1   . PHE A 1 258 ? -17.715 16.172  -52.820 1.000 24.260  0 257  PHE A CD1   1 ? 
ATOM   1952 C CD2   . PHE A 1 258 ? -16.209 17.959  -53.316 1.000 23.842  0 257  PHE A CD2   1 ? 
ATOM   1953 C CE1   . PHE A 1 258 ? -18.777 17.035  -52.910 1.000 25.111  0 257  PHE A CE1   1 ? 
ATOM   1954 C CE2   . PHE A 1 258 ? -17.289 18.828  -53.393 1.000 25.889  0 257  PHE A CE2   1 ? 
ATOM   1955 C CZ    . PHE A 1 258 ? -18.556 18.353  -53.191 1.000 25.826  0 257  PHE A CZ    1 ? 
ATOM   1956 N N     . MET A 1 259 ? -13.356 13.518  -55.400 1.000 25.382  0 258  MET A N     1 ? 
ATOM   1957 C CA    . MET A 1 259 ? -12.281 12.539  -55.424 1.000 26.755  0 258  MET A CA    1 ? 
ATOM   1958 C C     . MET A 1 259 ? -10.956 13.207  -55.760 1.000 27.156  0 258  MET A C     1 ? 
ATOM   1959 O O     . MET A 1 259 ? -9.908  12.556  -55.727 1.000 25.128  0 258  MET A O     1 ? 
ATOM   1960 C CB    . MET A 1 259 ? -12.508 11.443  -56.475 1.000 26.211  0 258  MET A CB    1 ? 
ATOM   1961 C CG    . MET A 1 259 ? -13.761 10.639  -56.271 1.000 30.088  0 258  MET A CG    1 ? 
ATOM   1962 S SD    . MET A 1 259 ? -13.865 9.785   -54.687 1.000 38.654  0 258  MET A SD    1 ? 
ATOM   1963 C CE    . MET A 1 259 ? -15.367 8.902   -55.078 1.000 39.859  0 258  MET A CE    1 ? 
ATOM   1964 N N     . LYS A 1 260 ? -11.002 14.510  -56.030 1.000 24.530  0 259  LYS A N     1 ? 
ATOM   1965 C CA    . LYS A 1 260 ? -9.791  15.266  -56.268 1.000 25.054  0 259  LYS A CA    1 ? 
ATOM   1966 C C     . LYS A 1 260 ? -9.428  16.072  -55.017 1.000 22.259  0 259  LYS A C     1 ? 
ATOM   1967 O O     . LYS A 1 260 ? -10.281 16.672  -54.369 1.000 25.818  0 259  LYS A O     1 ? 
ATOM   1968 C CB    . LYS A 1 260 ? -9.927  16.143  -57.505 1.000 26.690  0 259  LYS A CB    1 ? 
ATOM   1969 C CG    . LYS A 1 260 ? -9.851  15.419  -58.837 1.000 30.828  0 259  LYS A CG    1 ? 
ATOM   1970 C CD    . LYS A 1 260 ? -10.080 16.390  -59.997 1.000 36.645  0 259  LYS A CD    1 ? 
ATOM   1971 C CE    . LYS A 1 260 ? -10.206 15.732  -61.351 1.000 42.798  0 259  LYS A CE    1 ? 
ATOM   1972 N NZ    . LYS A 1 260 ? -9.106  14.796  -61.632 1.000 48.427  0 259  LYS A NZ    1 ? 
ATOM   1973 N N     . VAL A 1 261 ? -8.131  16.047  -54.716 1.000 20.682  0 260  VAL A N     1 ? 
ATOM   1974 C CA    . VAL A 1 261 ? -7.552  16.683  -53.550 1.000 20.738  0 260  VAL A CA    1 ? 
ATOM   1975 C C     . VAL A 1 261 ? -6.519  17.695  -54.036 1.000 20.784  0 260  VAL A C     1 ? 
ATOM   1976 O O     . VAL A 1 261 ? -5.516  17.357  -54.691 1.000 21.816  0 260  VAL A O     1 ? 
ATOM   1977 C CB    . VAL A 1 261 ? -6.929  15.649  -52.599 1.000 20.948  0 260  VAL A CB    1 ? 
ATOM   1978 C CG1   . VAL A 1 261 ? -6.343  16.328  -51.364 1.000 20.651  0 260  VAL A CG1   1 ? 
ATOM   1979 C CG2   . VAL A 1 261 ? -7.956  14.611  -52.204 1.000 21.433  0 260  VAL A CG2   1 ? 
ATOM   1980 N N     . GLU A 1 262 ? -6.775  18.955  -53.683 1.000 20.219  0 261  GLU A N     1 ? 
ATOM   1981 C CA    . GLU A 1 262 ? -5.884  20.038  -54.031 1.000 20.001  0 261  GLU A CA    1 ? 
ATOM   1982 C C     . GLU A 1 262 ? -5.016  20.387  -52.827 1.000 21.500  0 261  GLU A C     1 ? 
ATOM   1983 O O     . GLU A 1 262 ? -5.503  20.445  -51.692 1.000 23.398  0 261  GLU A O     1 ? 
ATOM   1984 C CB    . GLU A 1 262 ? -6.679  21.260  -54.472 1.000 21.429  0 261  GLU A CB    1 ? 
ATOM   1985 C CG    . GLU A 1 262 ? -5.802  22.421  -54.917 1.000 24.039  0 261  GLU A CG    1 ? 
ATOM   1986 C CD    . GLU A 1 262 ? -6.604  23.684  -55.161 1.000 28.739  0 261  GLU A CD    1 ? 
ATOM   1987 O OE1   . GLU A 1 262 ? -6.989  24.369  -54.190 1.000 26.689  0 261  GLU A OE1   1 ? 
ATOM   1988 O OE2   . GLU A 1 262 ? -6.809  23.974  -56.359 1.000 32.449  0 261  GLU A OE2   1 ? 
ATOM   1989 N N     . PHE A 1 263 ? -3.738  20.668  -53.096 1.000 20.737  0 262  PHE A N     1 ? 
ATOM   1990 C CA    . PHE A 1 263 ? -2.820  20.990  -52.011 1.000 22.853  0 262  PHE A CA    1 ? 
ATOM   1991 C C     . PHE A 1 263 ? -1.705  21.889  -52.511 1.000 19.322  0 262  PHE A C     1 ? 
ATOM   1992 O O     . PHE A 1 263 ? -1.478  22.025  -53.718 1.000 20.920  0 262  PHE A O     1 ? 
ATOM   1993 C CB    . PHE A 1 263 ? -2.223  19.703  -51.415 1.000 20.887  0 262  PHE A CB    1 ? 
ATOM   1994 C CG    . PHE A 1 263 ? -1.502  18.850  -52.443 1.000 21.274  0 262  PHE A CG    1 ? 
ATOM   1995 C CD1   . PHE A 1 263 ? -2.187  17.914  -53.203 1.000 21.967  0 262  PHE A CD1   1 ? 
ATOM   1996 C CD2   . PHE A 1 263 ? -0.138  19.004  -52.668 1.000 20.973  0 262  PHE A CD2   1 ? 
ATOM   1997 C CE1   . PHE A 1 263 ? -1.520  17.154  -54.151 1.000 23.510  0 262  PHE A CE1   1 ? 
ATOM   1998 C CE2   . PHE A 1 263 ? 0.522   18.251  -53.633 1.000 23.055  0 262  PHE A CE2   1 ? 
ATOM   1999 C CZ    . PHE A 1 263 ? -0.171  17.323  -54.362 1.000 22.482  0 262  PHE A CZ    1 ? 
ATOM   2000 N N     . ALA A 1 264 ? -0.999  22.461  -51.541 1.000 21.316  0 263  ALA A N     1 ? 
ATOM   2001 C CA    . ALA A 1 264 ? 0.134   23.344  -51.769 1.000 22.507  0 263  ALA A CA    1 ? 
ATOM   2002 C C     . ALA A 1 264 ? 1.036   23.380  -50.543 1.000 22.998  0 263  ALA A C     1 ? 
ATOM   2003 O O     . ALA A 1 264 ? 0.541   23.236  -49.446 1.000 22.779  0 263  ALA A O     1 ? 
ATOM   2004 C CB    . ALA A 1 264 ? -0.390  24.735  -52.085 1.000 22.732  0 263  ALA A CB    1 ? 
ATOM   2005 N N     . ARG A 1 265 ? 2.335   23.672  -50.735 1.000 24.784  0 264  ARG A N     1 ? 
ATOM   2006 C CA    . ARG A 1 265 ? 3.259   23.836  -49.618 1.000 26.721  0 264  ARG A CA    1 ? 
ATOM   2007 C C     . ARG A 1 265 ? 2.876   25.006  -48.718 1.000 28.416  0 264  ARG A C     1 ? 
ATOM   2008 O O     . ARG A 1 265 ? 2.986   24.905  -47.495 1.000 24.217  0 264  ARG A O     1 ? 
ATOM   2009 C CB    . ARG A 1 265 ? 4.680   23.974  -50.155 1.000 27.614  0 264  ARG A CB    1 ? 
ATOM   2010 C CG    . ARG A 1 265 ? 5.150   22.624  -50.691 1.000 31.442  0 264  ARG A CG    1 ? 
ATOM   2011 C CD    . ARG A 1 265 ? 6.525   22.702  -51.351 1.000 34.232  0 264  ARG A CD    1 ? 
ATOM   2012 N NE    . ARG A 1 265 ? 7.502   23.252  -50.404 1.000 34.226  0 264  ARG A NE    1 ? 
ATOM   2013 C CZ    . ARG A 1 265 ? 8.020   22.599  -49.357 1.000 38.094  0 264  ARG A CZ    1 ? 
ATOM   2014 N NH1   . ARG A 1 265 ? 8.718   23.262  -48.458 1.000 39.022  0 264  ARG A NH1   1 ? 
ATOM   2015 N NH2   . ARG A 1 265 ? 7.817   21.302  -49.185 1.000 36.926  0 264  ARG A NH2   1 ? 
ATOM   2016 N N     . ASP A 1 266 ? 2.394   26.098  -49.322 1.000 25.022  0 265  ASP A N     1 ? 
ATOM   2017 C CA    . ASP A 1 266 ? 2.058   27.306  -48.581 1.000 27.353  0 265  ASP A CA    1 ? 
ATOM   2018 C C     . ASP A 1 266 ? 1.202   28.190  -49.478 1.000 24.259  0 265  ASP A C     1 ? 
ATOM   2019 O O     . ASP A 1 266 ? 0.917   27.824  -50.625 1.000 20.572  0 265  ASP A O     1 ? 
ATOM   2020 C CB    . ASP A 1 266 ? 3.302   28.028  -48.075 1.000 30.282  0 265  ASP A CB    1 ? 
ATOM   2021 C CG    . ASP A 1 266 ? 4.322   28.416  -49.135 1.000 33.460  0 265  ASP A CG    1 ? 
ATOM   2022 O OD1   . ASP A 1 266 ? 3.945   29.040  -50.146 1.000 29.712  0 265  ASP A OD1   1 ? 
ATOM   2023 O OD2   . ASP A 1 266 ? 5.501   28.083  -48.946 1.000 43.914  0 265  ASP A OD2   1 ? 
ATOM   2024 N N     . ALA A 1 267 ? 0.804   29.346  -48.949 1.000 23.232  0 266  ALA A N     1 ? 
ATOM   2025 C CA    . ALA A 1 267 ? -0.185  30.184  -49.607 1.000 24.183  0 266  ALA A CA    1 ? 
ATOM   2026 C C     . ALA A 1 267 ? 0.310   30.702  -50.956 1.000 23.786  0 266  ALA A C     1 ? 
ATOM   2027 O O     . ALA A 1 267 ? -0.496  30.950  -51.851 1.000 23.927  0 266  ALA A O     1 ? 
ATOM   2028 C CB    . ALA A 1 267 ? -0.550  31.325  -48.693 1.000 28.069  0 266  ALA A CB    1 ? 
ATOM   2029 N N     . LEU A 1 268 ? 1.620   30.875  -51.104 1.000 24.830  0 267  LEU A N     1 ? 
ATOM   2030 C CA    . LEU A 1 268 ? 2.167   31.458  -52.324 1.000 28.663  0 267  LEU A CA    1 ? 
ATOM   2031 C C     . LEU A 1 268 ? 2.530   30.394  -53.355 1.000 29.381  0 267  LEU A C     1 ? 
ATOM   2032 O O     . LEU A 1 268 ? 2.837   30.720  -54.499 1.000 31.062  0 267  LEU A O     1 ? 
ATOM   2033 C CB    . LEU A 1 268 ? 3.371   32.299  -51.922 1.000 30.832  0 267  LEU A CB    1 ? 
ATOM   2034 C CG    . LEU A 1 268 ? 3.019   33.697  -51.401 1.000 35.245  0 267  LEU A CG    1 ? 
ATOM   2035 C CD1   . LEU A 1 268 ? 4.303   34.410  -51.072 1.000 38.064  0 267  LEU A CD1   1 ? 
ATOM   2036 C CD2   . LEU A 1 268 ? 2.192   34.481  -52.409 1.000 39.676  0 267  LEU A CD2   1 ? 
ATOM   2037 N N     . SER A 1 269 ? 2.442   29.119  -52.964 1.000 25.075  0 268  SER A N     1 ? 
ATOM   2038 C CA    . SER A 1 269 ? 2.887   28.012  -53.800 1.000 27.446  0 268  SER A CA    1 ? 
ATOM   2039 C C     . SER A 1 269 ? 1.807   27.597  -54.800 1.000 27.101  0 268  SER A C     1 ? 
ATOM   2040 O O     . SER A 1 269 ? 0.609   27.705  -54.549 1.000 29.428  0 268  SER A O     1 ? 
ATOM   2041 C CB    . SER A 1 269 ? 3.302   26.835  -52.941 1.000 28.775  0 268  SER A CB    1 ? 
ATOM   2042 O OG    . SER A 1 269 ? 4.591   27.061  -52.390 1.000 36.468  0 268  SER A OG    1 ? 
ATOM   2043 N N     . ALA A 1 270 ? 2.242   27.132  -55.968 1.000 28.823  0 269  ALA A N     1 ? 
ATOM   2044 C CA    . ALA A 1 270 ? 1.323   26.612  -56.971 1.000 32.465  0 269  ALA A CA    1 ? 
ATOM   2045 C C     . ALA A 1 270 ? 0.594   25.397  -56.384 1.000 29.003  0 269  ALA A C     1 ? 
ATOM   2046 O O     . ALA A 1 270 ? 1.219   24.605  -55.685 1.000 30.513  0 269  ALA A O     1 ? 
ATOM   2047 C CB    . ALA A 1 270 ? 2.100   26.222  -58.202 1.000 32.597  0 269  ALA A CB    1 ? 
ATOM   2048 N N     . ARG A 1 271 ? -0.707  25.299  -56.658 1.000 29.404  0 270  ARG A N     1 ? 
ATOM   2049 C CA    . ARG A 1 271 ? -1.531  24.202  -56.177 1.000 29.429  0 270  ARG A CA    1 ? 
ATOM   2050 C C     . ARG A 1 271 ? -1.363  23.007  -57.104 1.000 31.331  0 270  ARG A C     1 ? 
ATOM   2051 O O     . ARG A 1 271 ? -1.258  23.174  -58.315 1.000 28.739  0 270  ARG A O     1 ? 
ATOM   2052 C CB    . ARG A 1 271 ? -3.042  24.435  -56.204 1.000 31.304  0 270  ARG A CB    1 ? 
ATOM   2053 C CG    . ARG A 1 271 ? -3.636  25.680  -55.561 1.000 38.261  0 270  ARG A CG    1 ? 
ATOM   2054 C CD    . ARG A 1 271 ? -3.225  25.903  -54.144 1.000 38.078  0 270  ARG A CD    1 ? 
ATOM   2055 N NE    . ARG A 1 271 ? -3.811  27.130  -53.579 1.000 34.351  0 270  ARG A NE    1 ? 
ATOM   2056 C CZ    . ARG A 1 271 ? -3.186  28.093  -52.877 1.000 38.569  0 270  ARG A CZ    1 ? 
ATOM   2057 N NH1   . ARG A 1 271 ? -1.833  28.226  -52.790 1.000 31.938  0 270  ARG A NH1   1 ? 
ATOM   2058 N NH2   . ARG A 1 271 ? -3.991  28.960  -52.278 1.000 39.634  0 270  ARG A NH2   1 ? 
ATOM   2059 N N     . SER A 1 272 ? -1.389  21.806  -56.526 1.000 28.645  0 271  SER A N     1 ? 
ATOM   2060 C CA    . SER A 1 272 ? -1.447  20.571  -57.287 1.000 26.050  0 271  SER A CA    1 ? 
ATOM   2061 C C     . SER A 1 272 ? -2.686  19.777  -56.914 1.000 25.855  0 271  SER A C     1 ? 
ATOM   2062 O O     . SER A 1 272 ? -3.323  20.033  -55.887 1.000 21.956  0 271  SER A O     1 ? 
ATOM   2063 C CB    . SER A 1 272 ? -0.213  19.742  -57.103 1.000 27.115  0 271  SER A CB    1 ? 
ATOM   2064 O OG    . SER A 1 272 ? 0.930   20.534  -57.360 1.000 29.891  0 271  SER A OG    1 ? 
ATOM   2065 N N     . VAL A 1 273 ? -3.007  18.808  -57.775 1.000 22.531  0 272  VAL A N     1 ? 
ATOM   2066 C CA    . VAL A 1 273 ? -4.177  17.970  -57.593 1.000 25.005  0 272  VAL A CA    1 ? 
ATOM   2067 C C     . VAL A 1 273 ? -3.768  16.502  -57.748 1.000 26.661  0 272  VAL A C     1 ? 
ATOM   2068 O O     . VAL A 1 273 ? -3.058  16.152  -58.691 1.000 23.907  0 272  VAL A O     1 ? 
ATOM   2069 C CB    . VAL A 1 273 ? -5.294  18.329  -58.589 1.000 27.425  0 272  VAL A CB    1 ? 
ATOM   2070 C CG1   . VAL A 1 273 ? -6.481  17.386  -58.467 1.000 27.660  0 272  VAL A CG1   1 ? 
ATOM   2071 C CG2   . VAL A 1 273 ? -5.771  19.774  -58.437 1.000 27.798  0 272  VAL A CG2   1 ? 
ATOM   2072 N N     . VAL A 1 274 ? -4.235  15.660  -56.809 1.000 23.486  0 273  VAL A N     1 ? 
ATOM   2073 C CA    . VAL A 1 274 ? -4.189  14.219  -56.979 1.000 23.611  0 273  VAL A CA    1 ? 
ATOM   2074 C C     . VAL A 1 274 ? -5.616  13.677  -56.890 1.000 22.904  0 273  VAL A C     1 ? 
ATOM   2075 O O     . VAL A 1 274 ? -6.511  14.338  -56.378 1.000 23.063  0 273  VAL A O     1 ? 
ATOM   2076 C CB    . VAL A 1 274 ? -3.242  13.579  -55.949 1.000 24.726  0 273  VAL A CB    1 ? 
ATOM   2077 C CG1   . VAL A 1 274 ? -1.789  13.914  -56.228 1.000 25.732  0 273  VAL A CG1   1 ? 
ATOM   2078 C CG2   . VAL A 1 274 ? -3.630  13.978  -54.541 1.000 26.443  0 273  VAL A CG2   1 ? 
ATOM   2079 N N     . THR A 1 275 ? -5.819  12.452  -57.390 1.000 19.955  0 274  THR A N     1 ? 
ATOM   2080 C CA    . THR A 1 275 ? -7.136  11.846  -57.487 1.000 21.001  0 274  THR A CA    1 ? 
ATOM   2081 C C     . THR A 1 275 ? -7.149  10.495  -56.767 1.000 19.934  0 274  THR A C     1 ? 
ATOM   2082 O O     . THR A 1 275 ? -6.228  9.716   -56.925 1.000 21.742  0 274  THR A O     1 ? 
ATOM   2083 C CB    . THR A 1 275 ? -7.461  11.605  -58.964 1.000 24.385  0 274  THR A CB    1 ? 
ATOM   2084 O OG1   . THR A 1 275 ? -7.371  12.862  -59.632 1.000 28.257  0 274  THR A OG1   1 ? 
ATOM   2085 C CG2   . THR A 1 275 ? -8.883  11.128  -59.163 1.000 26.875  0 274  THR A CG2   1 ? 
ATOM   2086 N N     . ALA A 1 276 ? -8.253  10.204  -56.073 1.000 21.096  0 275  ALA A N     1 ? 
ATOM   2087 C CA    . ALA A 1 276 ? -8.499  8.884   -55.513 1.000 22.463  0 275  ALA A CA    1 ? 
ATOM   2088 C C     . ALA A 1 276 ? -9.494  8.179   -56.412 1.000 21.500  0 275  ALA A C     1 ? 
ATOM   2089 O O     . ALA A 1 276 ? -10.433 8.828   -56.859 1.000 23.208  0 275  ALA A O     1 ? 
ATOM   2090 C CB    . ALA A 1 276 ? -9.046  8.952   -54.085 1.000 19.503  0 275  ALA A CB    1 ? 
ATOM   2091 N N     . THR A 1 277 ? -9.320  6.856   -56.593 1.000 21.203  0 276  THR A N     1 ? 
ATOM   2092 C CA    . THR A 1 277 ? -10.289 6.072   -57.332 1.000 22.371  0 276  THR A CA    1 ? 
ATOM   2093 C C     . THR A 1 277 ? -11.300 5.403   -56.403 1.000 21.202  0 276  THR A C     1 ? 
ATOM   2094 O O     . THR A 1 277 ? -12.368 5.024   -56.871 1.000 21.410  0 276  THR A O     1 ? 
ATOM   2095 C CB    . THR A 1 277 ? -9.600  5.064   -58.242 1.000 25.628  0 276  THR A CB    1 ? 
ATOM   2096 O OG1   . THR A 1 277 ? -8.881  4.137   -57.438 1.000 23.009  0 276  THR A OG1   1 ? 
ATOM   2097 C CG2   . THR A 1 277 ? -8.649  5.726   -59.214 1.000 25.562  0 276  THR A CG2   1 ? 
ATOM   2098 N N     . LYS A 1 278 ? -11.032 5.288   -55.089 1.000 20.337  0 277  LYS A N     1 ? 
ATOM   2099 C CA    . LYS A 1 278 ? -11.980 4.607   -54.218 1.000 19.555  0 277  LYS A CA    1 ? 
ATOM   2100 C C     . LYS A 1 278 ? -12.538 5.571   -53.179 1.000 20.585  0 277  LYS A C     1 ? 
ATOM   2101 O O     . LYS A 1 278 ? -13.725 5.883   -53.187 1.000 20.936  0 277  LYS A O     1 ? 
ATOM   2102 C CB    . LYS A 1 278 ? -11.365 3.337   -53.621 1.000 20.379  0 277  LYS A CB    1 ? 
ATOM   2103 C CG    . LYS A 1 278 ? -10.889 2.329   -54.663 1.000 20.739  0 277  LYS A CG    1 ? 
ATOM   2104 C CD    . LYS A 1 278 ? -10.402 0.995   -54.101 1.000 21.959  0 277  LYS A CD    1 ? 
ATOM   2105 C CE    . LYS A 1 278 ? -10.118 0.143   -55.302 1.000 24.099  0 277  LYS A CE    1 ? 
ATOM   2106 N NZ    . LYS A 1 278 ? -9.581  -1.160  -54.959 1.000 28.110  0 277  LYS A NZ    1 ? 
ATOM   2107 N N     . GLU A 1 279 ? -11.682 6.098   -52.310 1.000 19.848  0 278  GLU A N     1 ? 
ATOM   2108 C CA    . GLU A 1 279 ? -12.167 7.091   -51.352 1.000 18.141  0 278  GLU A CA    1 ? 
ATOM   2109 C C     . GLU A 1 279 ? -11.093 8.108   -50.999 1.000 18.033  0 278  GLU A C     1 ? 
ATOM   2110 O O     . GLU A 1 279 ? -9.891  7.803   -50.978 1.000 19.233  0 278  GLU A O     1 ? 
ATOM   2111 C CB    . GLU A 1 279 ? -12.687 6.489   -50.043 1.000 20.011  0 278  GLU A CB    1 ? 
ATOM   2112 C CG    . GLU A 1 279 ? -13.843 5.501   -50.195 1.000 19.098  0 278  GLU A CG    1 ? 
ATOM   2113 C CD    . GLU A 1 279 ? -14.404 4.947   -48.886 1.000 22.047  0 278  GLU A CD    1 ? 
ATOM   2114 O OE1   . GLU A 1 279 ? -13.924 5.449   -47.851 1.000 20.091  0 278  GLU A OE1   1 ? 
ATOM   2115 O OE2   . GLU A 1 279 ? -15.344 4.104   -48.875 1.000 21.672  0 278  GLU A OE2   1 ? 
ATOM   2116 N N     . VAL A 1 280 ? -11.577 9.306   -50.613 1.000 16.967  0 279  VAL A N     1 ? 
ATOM   2117 C CA    . VAL A 1 280 ? -10.772 10.259  -49.882 1.000 18.548  0 279  VAL A CA    1 ? 
ATOM   2118 C C     . VAL A 1 280 ? -11.166 10.117  -48.411 1.000 16.203  0 279  VAL A C     1 ? 
ATOM   2119 O O     . VAL A 1 280 ? -12.351 10.068  -48.092 1.000 16.173  0 279  VAL A O     1 ? 
ATOM   2120 C CB    . VAL A 1 280 ? -11.012 11.693  -50.385 1.000 19.023  0 279  VAL A CB    1 ? 
ATOM   2121 C CG1   . VAL A 1 280 ? -10.352 12.742  -49.483 1.000 20.969  0 279  VAL A CG1   1 ? 
ATOM   2122 C CG2   . VAL A 1 280 ? -10.555 11.826  -51.834 1.000 20.640  0 279  VAL A CG2   1 ? 
ATOM   2123 N N     . VAL A 1 281 ? -10.171 9.976   -47.554 1.000 17.024  0 280  VAL A N     1 ? 
ATOM   2124 C CA    . VAL A 1 281 ? -10.356 9.946   -46.111 1.000 17.574  0 280  VAL A CA    1 ? 
ATOM   2125 C C     . VAL A 1 281 ? -9.762  11.229  -45.532 1.000 17.754  0 280  VAL A C     1 ? 
ATOM   2126 O O     . VAL A 1 281 ? -8.574  11.494  -45.670 1.000 18.905  0 280  VAL A O     1 ? 
ATOM   2127 C CB    . VAL A 1 281 ? -9.705  8.707   -45.471 1.000 18.474  0 280  VAL A CB    1 ? 
ATOM   2128 C CG1   . VAL A 1 281 ? -9.890  8.657   -43.955 1.000 19.810  0 280  VAL A CG1   1 ? 
ATOM   2129 C CG2   . VAL A 1 281 ? -10.213 7.419   -46.110 1.000 20.349  0 280  VAL A CG2   1 ? 
ATOM   2130 N N     . LEU A 1 282 ? -10.594 11.984  -44.810 1.000 18.615  0 281  LEU A N     1 ? 
ATOM   2131 C CA    . LEU A 1 282 ? -10.159 13.146  -44.059 1.000 17.537  0 281  LEU A CA    1 ? 
ATOM   2132 C C     . LEU A 1 282 ? -9.821  12.741  -42.629 1.000 17.966  0 281  LEU A C     1 ? 
ATOM   2133 O O     . LEU A 1 282 ? -10.678 12.232  -41.926 1.000 17.289  0 281  LEU A O     1 ? 
ATOM   2134 C CB    . LEU A 1 282 ? -11.261 14.203  -44.078 1.000 17.898  0 281  LEU A CB    1 ? 
ATOM   2135 C CG    . LEU A 1 282 ? -11.643 14.757  -45.448 1.000 21.294  0 281  LEU A CG    1 ? 
ATOM   2136 C CD1   . LEU A 1 282 ? -12.687 15.832  -45.243 1.000 20.810  0 281  LEU A CD1   1 ? 
ATOM   2137 C CD2   . LEU A 1 282 ? -10.437 15.282  -46.189 1.000 22.965  0 281  LEU A CD2   1 ? 
ATOM   2138 N N     . SER A 1 283 ? -8.549  12.965  -42.255 1.000 17.241  0 282  SER A N     1 ? 
ATOM   2139 C CA    . SER A 1 283 ? -8.032  12.699  -40.919 1.000 17.524  0 282  SER A CA    1 ? 
ATOM   2140 C C     . SER A 1 283 ? -7.246  13.912  -40.440 1.000 16.818  0 282  SER A C     1 ? 
ATOM   2141 O O     . SER A 1 283 ? -6.234  13.791  -39.742 1.000 18.161  0 282  SER A O     1 ? 
ATOM   2142 C CB    . SER A 1 283 ? -7.144  11.452  -40.908 1.000 18.041  0 282  SER A CB    1 ? 
ATOM   2143 O OG    . SER A 1 283 ? -7.864  10.300  -41.309 1.000 20.477  0 282  SER A OG    1 ? 
ATOM   2144 N N     . ALA A 1 284 ? -7.738  15.098  -40.808 1.000 16.846  0 283  ALA A N     1 ? 
ATOM   2145 C CA    . ALA A 1 284 ? -7.053  16.343  -40.530 1.000 16.676  0 283  ALA A CA    1 ? 
ATOM   2146 C C     . ALA A 1 284 ? -7.442  16.879  -39.150 1.000 16.167  0 283  ALA A C     1 ? 
ATOM   2147 O O     . ALA A 1 284 ? -7.035  17.965  -38.769 1.000 17.841  0 283  ALA A O     1 ? 
ATOM   2148 C CB    . ALA A 1 284 ? -7.353  17.370  -41.602 1.000 17.609  0 283  ALA A CB    1 ? 
ATOM   2149 N N     . GLY A 1 285 ? -8.191  16.102  -38.371 1.000 17.956  0 284  GLY A N     1 ? 
ATOM   2150 C CA    . GLY A 1 285 ? -8.474  16.477  -36.990 1.000 18.426  0 284  GLY A CA    1 ? 
ATOM   2151 C C     . GLY A 1 285 ? -9.726  17.352  -36.864 1.000 17.657  0 284  GLY A C     1 ? 
ATOM   2152 O O     . GLY A 1 285 ? -10.311 17.802  -37.851 1.000 18.488  0 284  GLY A O     1 ? 
ATOM   2153 N N     . SER A 1 286 ? -10.083 17.652  -35.632 1.000 16.425  0 285  SER A N     1 ? 
ATOM   2154 C CA    . SER A 1 286 ? -11.333 18.345  -35.314 1.000 17.516  0 285  SER A CA    1 ? 
ATOM   2155 C C     . SER A 1 286 ? -11.347 19.795  -35.789 1.000 17.781  0 285  SER A C     1 ? 
ATOM   2156 O O     . SER A 1 286 ? -12.416 20.396  -35.817 1.000 20.275  0 285  SER A O     1 ? 
ATOM   2157 C CB    . SER A 1 286 ? -11.581 18.296  -33.825 1.000 18.868  0 285  SER A CB    1 ? 
ATOM   2158 O OG    . SER A 1 286 ? -11.840 16.953  -33.397 1.000 22.417  0 285  SER A OG    1 ? 
ATOM   2159 N N     . ILE A 1 287 ? -10.180 20.399  -36.074 1.000 19.181  0 286  ILE A N     1 ? 
ATOM   2160 C CA    . ILE A 1 287 ? -10.141 21.742  -36.647 1.000 19.831  0 286  ILE A CA    1 ? 
ATOM   2161 C C     . ILE A 1 287 ? -9.906  21.670  -38.162 1.000 21.488  0 286  ILE A C     1 ? 
ATOM   2162 O O     . ILE A 1 287 ? -10.624 22.291  -38.949 1.000 22.332  0 286  ILE A O     1 ? 
ATOM   2163 C CB    . ILE A 1 287 ? -9.114  22.613  -35.911 1.000 21.083  0 286  ILE A CB    1 ? 
ATOM   2164 C CG1   . ILE A 1 287 ? -9.506  22.754  -34.437 1.000 24.471  0 286  ILE A CG1   1 ? 
ATOM   2165 C CG2   . ILE A 1 287 ? -8.948  23.985  -36.591 1.000 21.346  0 286  ILE A CG2   1 ? 
ATOM   2166 C CD1   . ILE A 1 287 ? -8.502  23.515  -33.597 1.000 26.499  0 286  ILE A CD1   1 ? 
ATOM   2167 N N     . GLY A 1 288 ? -8.925  20.882  -38.593 1.000 20.665  0 287  GLY A N     1 ? 
ATOM   2168 C CA    . GLY A 1 288 ? -8.585  20.800  -40.013 1.000 19.271  0 287  GLY A CA    1 ? 
ATOM   2169 C C     . GLY A 1 288 ? -9.695  20.215  -40.883 1.000 18.795  0 287  GLY A C     1 ? 
ATOM   2170 O O     . GLY A 1 288 ? -9.883  20.676  -42.013 1.000 20.066  0 287  GLY A O     1 ? 
ATOM   2171 N N     . THR A 1 289 ? -10.369 19.158  -40.417 1.000 18.010  0 288  THR A N     1 ? 
ATOM   2172 C CA    . THR A 1 289 ? -11.342 18.429  -41.235 1.000 19.092  0 288  THR A CA    1 ? 
ATOM   2173 C C     . THR A 1 289 ? -12.556 19.321  -41.542 1.000 20.031  0 288  THR A C     1 ? 
ATOM   2174 O O     . THR A 1 289 ? -12.944 19.463  -42.708 1.000 18.021  0 288  THR A O     1 ? 
ATOM   2175 C CB    . THR A 1 289 ? -11.753 17.121  -40.544 1.000 18.860  0 288  THR A CB    1 ? 
ATOM   2176 O OG1   . THR A 1 289 ? -10.659 16.213  -40.682 1.000 19.092  0 288  THR A OG1   1 ? 
ATOM   2177 C CG2   . THR A 1 289 ? -13.031 16.518  -41.111 1.000 18.774  0 288  THR A CG2   1 ? 
ATOM   2178 N N     . PRO A 1 290 ? -13.212 19.969  -40.559 1.000 19.878  0 289  PRO A N     1 ? 
ATOM   2179 C CA    . PRO A 1 290 ? -14.275 20.907  -40.905 1.000 18.672  0 289  PRO A CA    1 ? 
ATOM   2180 C C     . PRO A 1 290 ? -13.821 22.068  -41.791 1.000 20.080  0 289  PRO A C     1 ? 
ATOM   2181 O O     . PRO A 1 290 ? -14.592 22.529  -42.638 1.000 20.156  0 289  PRO A O     1 ? 
ATOM   2182 C CB    . PRO A 1 290 ? -14.833 21.368  -39.538 1.000 20.961  0 289  PRO A CB    1 ? 
ATOM   2183 C CG    . PRO A 1 290 ? -13.768 21.056  -38.543 1.000 21.893  0 289  PRO A CG    1 ? 
ATOM   2184 C CD    . PRO A 1 290 ? -13.026 19.832  -39.098 1.000 20.438  0 289  PRO A CD    1 ? 
ATOM   2185 N N     . GLN A 1 291 ? -12.573 22.524  -41.645 1.000 18.979  0 290  GLN A N     1 ? 
ATOM   2186 C CA    . GLN A 1 291 ? -12.106 23.626  -42.470 1.000 20.430  0 290  GLN A CA    1 ? 
ATOM   2187 C C     . GLN A 1 291 ? -12.005 23.173  -43.916 1.000 21.067  0 290  GLN A C     1 ? 
ATOM   2188 O O     . GLN A 1 291 ? -12.448 23.879  -44.810 1.000 20.342  0 290  GLN A O     1 ? 
ATOM   2189 C CB    . GLN A 1 291 ? -10.762 24.195  -42.012 1.000 24.682  0 290  GLN A CB    1 ? 
ATOM   2190 C CG    . GLN A 1 291 ? -10.370 25.437  -42.803 1.000 27.785  0 290  GLN A CG    1 ? 
ATOM   2191 C CD    . GLN A 1 291 ? -9.280  26.243  -42.142 1.000 32.677  0 290  GLN A CD    1 ? 
ATOM   2192 O OE1   . GLN A 1 291 ? -8.557  25.739  -41.272 1.000 35.890  0 290  GLN A OE1   1 ? 
ATOM   2193 N NE2   . GLN A 1 291 ? -9.138  27.489  -42.578 1.000 34.109  0 290  GLN A NE2   1 ? 
ATOM   2194 N N     . ILE A 1 292 ? -11.436 21.990  -44.157 1.000 18.332  0 291  ILE A N     1 ? 
ATOM   2195 C CA    . ILE A 1 292 ? -11.430 21.428  -45.513 1.000 20.260  0 291  ILE A CA    1 ? 
ATOM   2196 C C     . ILE A 1 292 ? -12.850 21.257  -46.064 1.000 18.778  0 291  ILE A C     1 ? 
ATOM   2197 O O     . ILE A 1 292 ? -13.107 21.549  -47.245 1.000 19.768  0 291  ILE A O     1 ? 
ATOM   2198 C CB    . ILE A 1 292 ? -10.630 20.109  -45.588 1.000 20.100  0 291  ILE A CB    1 ? 
ATOM   2199 C CG1   . ILE A 1 292 ? -9.161  20.324  -45.257 1.000 21.051  0 291  ILE A CG1   1 ? 
ATOM   2200 C CG2   . ILE A 1 292 ? -10.798 19.430  -46.957 1.000 19.064  0 291  ILE A CG2   1 ? 
ATOM   2201 C CD1   . ILE A 1 292 ? -8.417  19.046  -44.931 1.000 21.395  0 291  ILE A CD1   1 ? 
ATOM   2202 N N     . LEU A 1 293 ? -13.759 20.693  -45.279 1.000 19.198  0 292  LEU A N     1 ? 
ATOM   2203 C CA    . LEU A 1 293 ? -15.121 20.446  -45.740 1.000 19.591  0 292  LEU A CA    1 ? 
ATOM   2204 C C     . LEU A 1 293 ? -15.785 21.765  -46.144 1.000 20.168  0 292  LEU A C     1 ? 
ATOM   2205 O O     . LEU A 1 293 ? -16.262 21.909  -47.273 1.000 21.026  0 292  LEU A O     1 ? 
ATOM   2206 C CB    . LEU A 1 293 ? -15.945 19.728  -44.678 1.000 19.515  0 292  LEU A CB    1 ? 
ATOM   2207 C CG    . LEU A 1 293 ? -15.596 18.256  -44.445 1.000 19.177  0 292  LEU A CG    1 ? 
ATOM   2208 C CD1   . LEU A 1 293 ? -16.304 17.661  -43.257 1.000 18.263  0 292  LEU A CD1   1 ? 
ATOM   2209 C CD2   . LEU A 1 293 ? -15.866 17.373  -45.663 1.000 19.307  0 292  LEU A CD2   1 ? 
ATOM   2210 N N     . MET A 1 294 ? -15.697 22.762  -45.271 1.000 19.949  0 293  MET A N     1 ? 
ATOM   2211 C CA    . MET A 1 294 ? -16.308 24.061  -45.534 1.000 21.328  0 293  MET A CA    1 ? 
ATOM   2212 C C     . MET A 1 294 ? -15.729 24.705  -46.804 1.000 21.206  0 293  MET A C     1 ? 
ATOM   2213 O O     . MET A 1 294 ? -16.476 25.208  -47.625 1.000 21.790  0 293  MET A O     1 ? 
ATOM   2214 C CB    . MET A 1 294 ? -16.172 24.950  -44.294 1.000 21.521  0 293  MET A CB    1 ? 
ATOM   2215 C CG    . MET A 1 294 ? -16.985 24.420  -43.154 1.000 21.856  0 293  MET A CG    1 ? 
ATOM   2216 S SD    . MET A 1 294 ? -16.978 25.504  -41.714 1.000 27.867  0 293  MET A SD    1 ? 
ATOM   2217 C CE    . MET A 1 294 ? -15.238 25.479  -41.304 1.000 27.143  0 293  MET A CE    1 ? 
ATOM   2218 N N     . LEU A 1 295 ? -14.406 24.673  -46.991 1.000 20.175  0 294  LEU A N     1 ? 
ATOM   2219 C CA    . LEU A 1 295 ? -13.786 25.309  -48.137 1.000 20.909  0 294  LEU A CA    1 ? 
ATOM   2220 C C     . LEU A 1 295 ? -14.139 24.557  -49.415 1.000 21.798  0 294  LEU A C     1 ? 
ATOM   2221 O O     . LEU A 1 295 ? -14.109 25.163  -50.489 1.000 21.141  0 294  LEU A O     1 ? 
ATOM   2222 C CB    . LEU A 1 295 ? -12.278 25.411  -47.969 1.000 20.417  0 294  LEU A CB    1 ? 
ATOM   2223 C CG    . LEU A 1 295 ? -11.791 26.389  -46.898 1.000 23.667  0 294  LEU A CG    1 ? 
ATOM   2224 C CD1   . LEU A 1 295 ? -10.370 26.026  -46.501 1.000 24.866  0 294  LEU A CD1   1 ? 
ATOM   2225 C CD2   . LEU A 1 295 ? -11.892 27.820  -47.415 1.000 28.356  0 294  LEU A CD2   1 ? 
ATOM   2226 N N     . SER A 1 296 ? -14.552 23.295  -49.278 1.000 19.766  0 295  SER A N     1 ? 
ATOM   2227 C CA    . SER A 1 296 ? -14.981 22.446  -50.383 1.000 20.963  0 295  SER A CA    1 ? 
ATOM   2228 C C     . SER A 1 296 ? -16.444 22.664  -50.732 1.000 21.295  0 295  SER A C     1 ? 
ATOM   2229 O O     . SER A 1 296 ? -16.920 22.066  -51.700 1.000 23.457  0 295  SER A O     1 ? 
ATOM   2230 C CB    . SER A 1 296 ? -14.728 20.998  -50.051 1.000 20.424  0 295  SER A CB    1 ? 
ATOM   2231 O OG    . SER A 1 296 ? -13.334 20.801  -49.820 1.000 21.854  0 295  SER A OG    1 ? 
ATOM   2232 N N     . GLY A 1 297 ? -17.135 23.502  -49.939 1.000 21.512  0 296  GLY A N     1 ? 
ATOM   2233 C CA    . GLY A 1 297 ? -18.549 23.797  -50.124 1.000 23.342  0 296  GLY A CA    1 ? 
ATOM   2234 C C     . GLY A 1 297 ? -19.477 22.756  -49.522 1.000 25.035  0 296  GLY A C     1 ? 
ATOM   2235 O O     . GLY A 1 297 ? -20.611 22.636  -49.968 1.000 25.179  0 296  GLY A O     1 ? 
ATOM   2236 N N     . ILE A 1 298 ? -18.974 22.016  -48.516 1.000 22.580  0 297  ILE A N     1 ? 
ATOM   2237 C CA    . ILE A 1 298 ? -19.733 21.039  -47.770 1.000 21.595  0 297  ILE A CA    1 ? 
ATOM   2238 C C     . ILE A 1 298 ? -19.919 21.589  -46.361 1.000 21.516  0 297  ILE A C     1 ? 
ATOM   2239 O O     . ILE A 1 298 ? -18.978 21.652  -45.603 1.000 23.931  0 297  ILE A O     1 ? 
ATOM   2240 C CB    . ILE A 1 298 ? -18.986 19.692  -47.750 1.000 22.245  0 297  ILE A CB    1 ? 
ATOM   2241 C CG1   . ILE A 1 298 ? -18.658 19.230  -49.167 1.000 24.414  0 297  ILE A CG1   1 ? 
ATOM   2242 C CG2   . ILE A 1 298 ? -19.779 18.644  -46.973 1.000 22.581  0 297  ILE A CG2   1 ? 
ATOM   2243 C CD1   . ILE A 1 298 ? -17.586 18.151  -49.231 1.000 24.604  0 297  ILE A CD1   1 ? 
ATOM   2244 N N     . GLY A 1 299 ? -21.124 22.039  -46.021 1.000 19.644  0 298  GLY A N     1 ? 
ATOM   2245 C CA    . GLY A 1 299 ? -21.330 22.675  -44.732 1.000 20.702  0 298  GLY A CA    1 ? 
ATOM   2246 C C     . GLY A 1 299 ? -22.642 23.441  -44.702 1.000 22.703  0 298  GLY A C     1 ? 
ATOM   2247 O O     . GLY A 1 299 ? -23.497 23.246  -45.559 1.000 22.790  0 298  GLY A O     1 ? 
ATOM   2248 N N     . ASP A 1 300 ? -22.749 24.361  -43.747 1.000 23.707  0 299  ASP A N     1 ? 
ATOM   2249 C CA    . ASP A 1 300 ? -23.970 25.129  -43.583 1.000 25.228  0 299  ASP A CA    1 ? 
ATOM   2250 C C     . ASP A 1 300 ? -24.149 26.091  -44.758 1.000 24.175  0 299  ASP A C     1 ? 
ATOM   2251 O O     . ASP A 1 300 ? -23.355 27.014  -44.945 1.000 21.106  0 299  ASP A O     1 ? 
ATOM   2252 C CB    . ASP A 1 300 ? -23.906 25.925  -42.302 1.000 28.334  0 299  ASP A CB    1 ? 
ATOM   2253 C CG    . ASP A 1 300 ? -25.219 26.606  -41.957 1.000 35.303  0 299  ASP A CG    1 ? 
ATOM   2254 O OD1   . ASP A 1 300 ? -25.694 27.434  -42.768 1.000 34.831  0 299  ASP A OD1   1 ? 
ATOM   2255 O OD2   . ASP A 1 300 ? -25.727 26.313  -40.882 1.000 33.395  0 299  ASP A OD2   1 ? 
ATOM   2256 N N     . ARG A 1 301 ? -25.203 25.877  -45.541 1.000 25.875  0 300  ARG A N     1 ? 
ATOM   2257 C CA    . ARG A 1 301 ? -25.370 26.614  -46.789 1.000 30.359  0 300  ARG A CA    1 ? 
ATOM   2258 C C     . ARG A 1 301 ? -25.384 28.117  -46.513 1.000 31.683  0 300  ARG A C     1 ? 
ATOM   2259 O O     . ARG A 1 301 ? -24.654 28.857  -47.170 1.000 29.382  0 300  ARG A O     1 ? 
ATOM   2260 C CB    . ARG A 1 301 ? -26.641 26.227  -47.559 1.000 36.304  0 300  ARG A CB    1 ? 
ATOM   2261 C CG    . ARG A 1 301 ? -26.835 27.030  -48.845 1.000 42.322  0 300  ARG A CG    1 ? 
ATOM   2262 C CD    . ARG A 1 301 ? -28.096 26.676  -49.626 1.000 46.008  0 300  ARG A CD    1 ? 
ATOM   2263 N NE    . ARG A 1 301 ? -27.948 25.329  -50.187 1.000 56.095  0 300  ARG A NE    1 ? 
ATOM   2264 C CZ    . ARG A 1 301 ? -27.156 24.967  -51.200 1.000 59.904  0 300  ARG A CZ    1 ? 
ATOM   2265 N NH1   . ARG A 1 301 ? -26.602 25.887  -51.982 1.000 55.290  0 300  ARG A NH1   1 ? 
ATOM   2266 N NH2   . ARG A 1 301 ? -26.964 23.673  -51.451 1.000 59.093  0 300  ARG A NH2   1 ? 
ATOM   2267 N N     . GLU A 1 302 ? -26.166 28.552  -45.505 1.000 32.263  0 301  GLU A N     1 ? 
ATOM   2268 C CA    . GLU A 1 302 ? -26.366 29.982  -45.261 1.000 35.478  0 301  GLU A CA    1 ? 
ATOM   2269 C C     . GLU A 1 302 ? -25.063 30.647  -44.832 1.000 33.335  0 301  GLU A C     1 ? 
ATOM   2270 O O     . GLU A 1 302 ? -24.680 31.677  -45.371 1.000 31.269  0 301  GLU A O     1 ? 
ATOM   2271 C CB    . GLU A 1 302 ? -27.361 30.283  -44.141 1.000 41.887  0 301  GLU A CB    1 ? 
ATOM   2272 C CG    . GLU A 1 302 ? -28.782 29.798  -44.396 1.000 56.092  0 301  GLU A CG    1 ? 
ATOM   2273 C CD    . GLU A 1 302 ? -29.552 29.719  -43.082 1.000 69.518  0 301  GLU A CD    1 ? 
ATOM   2274 O OE1   . GLU A 1 302 ? -29.496 30.712  -42.311 1.000 73.854  0 301  GLU A OE1   1 ? 
ATOM   2275 O OE2   . GLU A 1 302 ? -30.185 28.669  -42.816 1.000 70.548  0 301  GLU A OE2   1 ? 
ATOM   2276 N N     . GLU A 1 303 ? -24.385 30.039  -43.852 1.000 26.846  0 302  GLU A N     1 ? 
ATOM   2277 C CA    . GLU A 1 303 ? -23.156 30.584  -43.310 1.000 30.725  0 302  GLU A CA    1 ? 
ATOM   2278 C C     . GLU A 1 303 ? -22.039 30.599  -44.347 1.000 29.210  0 302  GLU A C     1 ? 
ATOM   2279 O O     . GLU A 1 303 ? -21.289 31.565  -44.435 1.000 31.355  0 302  GLU A O     1 ? 
ATOM   2280 C CB    . GLU A 1 303 ? -22.704 29.757  -42.102 1.000 33.136  0 302  GLU A CB    1 ? 
ATOM   2281 C CG    . GLU A 1 303 ? -23.695 29.797  -40.943 1.000 33.454  0 302  GLU A CG    1 ? 
ATOM   2282 C CD    . GLU A 1 303 ? -23.163 29.217  -39.639 1.000 43.959  0 302  GLU A CD    1 ? 
ATOM   2283 O OE1   . GLU A 1 303 ? -22.066 28.603  -39.632 1.000 44.376  0 302  GLU A OE1   1 ? 
ATOM   2284 O OE2   . GLU A 1 303 ? -23.854 29.393  -38.610 1.000 39.373  0 302  GLU A OE2   1 ? 
ATOM   2285 N N     . LEU A 1 304 ? -21.910 29.538  -45.137 1.000 27.055  0 303  LEU A N     1 ? 
ATOM   2286 C CA    . LEU A 1 304 ? -20.824 29.472  -46.098 1.000 27.813  0 303  LEU A CA    1 ? 
ATOM   2287 C C     . LEU A 1 304 ? -21.053 30.450  -47.254 1.000 25.570  0 303  LEU A C     1 ? 
ATOM   2288 O O     . LEU A 1 304 ? -20.100 31.038  -47.750 1.000 26.255  0 303  LEU A O     1 ? 
ATOM   2289 C CB    . LEU A 1 304 ? -20.640 28.045  -46.607 1.000 29.353  0 303  LEU A CB    1 ? 
ATOM   2290 C CG    . LEU A 1 304 ? -20.156 27.047  -45.546 1.000 31.832  0 303  LEU A CG    1 ? 
ATOM   2291 C CD1   . LEU A 1 304 ? -20.043 25.694  -46.171 1.000 33.947  0 303  LEU A CD1   1 ? 
ATOM   2292 C CD2   . LEU A 1 304 ? -18.834 27.517  -44.968 1.000 34.490  0 303  LEU A CD2   1 ? 
ATOM   2293 N N     . THR A 1 305 ? -22.306 30.573  -47.708 1.000 29.206  0 304  THR A N     1 ? 
ATOM   2294 C CA    . THR A 1 305 ? -22.650 31.528  -48.754 1.000 29.754  0 304  THR A CA    1 ? 
ATOM   2295 C C     . THR A 1 305 ? -22.250 32.934  -48.306 1.000 30.515  0 304  THR A C     1 ? 
ATOM   2296 O O     . THR A 1 305 ? -21.697 33.705  -49.092 1.000 34.197  0 304  THR A O     1 ? 
ATOM   2297 C CB    . THR A 1 305 ? -24.145 31.438  -49.087 1.000 31.874  0 304  THR A CB    1 ? 
ATOM   2298 O OG1   . THR A 1 305 ? -24.369 30.163  -49.679 1.000 33.586  0 304  THR A OG1   1 ? 
ATOM   2299 C CG2   . THR A 1 305 ? -24.581 32.498  -50.085 1.000 33.326  0 304  THR A CG2   1 ? 
ATOM   2300 N N     . ALA A 1 306 ? -22.464 33.258  -47.025 1.000 29.158  0 305  ALA A N     1 ? 
ATOM   2301 C CA    . ALA A 1 306 ? -22.133 34.587  -46.519 1.000 32.544  0 305  ALA A CA    1 ? 
ATOM   2302 C C     . ALA A 1 306 ? -20.634 34.860  -46.602 1.000 33.373  0 305  ALA A C     1 ? 
ATOM   2303 O O     . ALA A 1 306 ? -20.235 35.994  -46.800 1.000 39.074  0 305  ALA A O     1 ? 
ATOM   2304 C CB    . ALA A 1 306 ? -22.625 34.761  -45.089 1.000 34.941  0 305  ALA A CB    1 ? 
ATOM   2305 N N     . ILE A 1 307 ? -19.811 33.820  -46.445 1.000 33.186  0 306  ILE A N     1 ? 
ATOM   2306 C CA    . ILE A 1 307 ? -18.356 33.917  -46.466 1.000 35.147  0 306  ILE A CA    1 ? 
ATOM   2307 C C     . ILE A 1 307 ? -17.869 33.959  -47.917 1.000 35.162  0 306  ILE A C     1 ? 
ATOM   2308 O O     . ILE A 1 307 ? -16.724 34.293  -48.180 1.000 41.362  0 306  ILE A O     1 ? 
ATOM   2309 C CB    . ILE A 1 307 ? -17.762 32.730  -45.669 1.000 37.930  0 306  ILE A CB    1 ? 
ATOM   2310 C CG1   . ILE A 1 307 ? -17.727 33.029  -44.175 1.000 44.026  0 306  ILE A CG1   1 ? 
ATOM   2311 C CG2   . ILE A 1 307 ? -16.387 32.298  -46.180 1.000 42.853  0 306  ILE A CG2   1 ? 
ATOM   2312 C CD1   . ILE A 1 307 ? -16.771 34.143  -43.764 1.000 44.829  0 306  ILE A CD1   1 ? 
ATOM   2313 N N     . GLY A 1 308 ? -18.744 33.585  -48.852 1.000 34.091  0 307  GLY A N     1 ? 
ATOM   2314 C CA    . GLY A 1 308 ? -18.429 33.626  -50.265 1.000 33.965  0 307  GLY A CA    1 ? 
ATOM   2315 C C     . GLY A 1 308 ? -17.972 32.267  -50.793 1.000 34.862  0 307  GLY A C     1 ? 
ATOM   2316 O O     . GLY A 1 308 ? -17.327 32.202  -51.823 1.000 33.219  0 307  GLY A O     1 ? 
ATOM   2317 N N     . VAL A 1 309 ? -18.282 31.182  -50.081 1.000 33.565  0 308  VAL A N     1 ? 
ATOM   2318 C CA    . VAL A 1 309 ? -18.036 29.849  -50.608 1.000 32.273  0 308  VAL A CA    1 ? 
ATOM   2319 C C     . VAL A 1 309 ? -19.223 29.448  -51.477 1.000 31.631  0 308  VAL A C     1 ? 
ATOM   2320 O O     . VAL A 1 309 ? -20.371 29.623  -51.071 1.000 31.196  0 308  VAL A O     1 ? 
ATOM   2321 C CB    . VAL A 1 309 ? -17.802 28.837  -49.466 1.000 32.336  0 308  VAL A CB    1 ? 
ATOM   2322 C CG1   . VAL A 1 309 ? -17.784 27.398  -49.986 1.000 32.396  0 308  VAL A CG1   1 ? 
ATOM   2323 C CG2   . VAL A 1 309 ? -16.513 29.168  -48.729 1.000 32.796  0 308  VAL A CG2   1 ? 
ATOM   2324 N N     . ASN A 1 310 ? -18.920 28.910  -52.667 1.000 36.109  0 309  ASN A N     1 ? 
ATOM   2325 C CA    . ASN A 1 310 ? -19.898 28.201  -53.480 1.000 36.886  0 309  ASN A CA    1 ? 
ATOM   2326 C C     . ASN A 1 310 ? -20.217 26.876  -52.794 1.000 35.870  0 309  ASN A C     1 ? 
ATOM   2327 O O     . ASN A 1 310 ? -19.339 26.024  -52.636 1.000 34.034  0 309  ASN A O     1 ? 
ATOM   2328 C CB    . ASN A 1 310 ? -19.396 28.019  -54.912 1.000 44.609  0 309  ASN A CB    1 ? 
ATOM   2329 C CG    . ASN A 1 310 ? -19.142 29.332  -55.631 1.000 49.882  0 309  ASN A CG    1 ? 
ATOM   2330 O OD1   . ASN A 1 310 ? -19.776 30.351  -55.332 1.000 50.095  0 309  ASN A OD1   1 ? 
ATOM   2331 N ND2   . ASN A 1 310 ? -18.219 29.340  -56.581 1.000 50.526  0 309  ASN A ND2   1 ? 
ATOM   2332 N N     . VAL A 1 311 ? -21.459 26.729  -52.346 1.000 34.652  0 310  VAL A N     1 ? 
ATOM   2333 C CA    . VAL A 1 311 ? -21.858 25.597  -51.534 1.000 38.656  0 310  VAL A CA    1 ? 
ATOM   2334 C C     . VAL A 1 311 ? -22.446 24.531  -52.445 1.000 47.929  0 310  VAL A C     1 ? 
ATOM   2335 O O     . VAL A 1 311 ? -23.309 24.834  -53.265 1.000 55.590  0 310  VAL A O     1 ? 
ATOM   2336 C CB    . VAL A 1 311 ? -22.879 25.942  -50.445 1.000 41.150  0 310  VAL A CB    1 ? 
ATOM   2337 C CG1   . VAL A 1 311 ? -23.335 24.699  -49.692 1.000 39.224  0 310  VAL A CG1   1 ? 
ATOM   2338 C CG2   . VAL A 1 311 ? -22.335 26.988  -49.485 1.000 45.374  0 310  VAL A CG2   1 ? 
ATOM   2339 N N     . THR A 1 312 ? -22.019 23.285  -52.229 1.000 38.000  0 311  THR A N     1 ? 
ATOM   2340 C CA    . THR A 1 312 ? -22.400 22.177  -53.087 1.000 42.334  0 311  THR A CA    1 ? 
ATOM   2341 C C     . THR A 1 312 ? -23.215 21.150  -52.313 1.000 39.038  0 311  THR A C     1 ? 
ATOM   2342 O O     . THR A 1 312 ? -24.104 20.535  -52.871 1.000 38.779  0 311  THR A O     1 ? 
ATOM   2343 C CB    . THR A 1 312 ? -21.150 21.557  -53.700 1.000 50.066  0 311  THR A CB    1 ? 
ATOM   2344 O OG1   . THR A 1 312 ? -21.655 20.355  -54.275 1.000 61.136  0 311  THR A OG1   1 ? 
ATOM   2345 C CG2   . THR A 1 312 ? -20.071 21.283  -52.666 1.000 52.503  0 311  THR A CG2   1 ? 
ATOM   2346 N N     . VAL A 1 313 ? -22.934 20.967  -51.025 1.000 30.138  0 312  VAL A N     1 ? 
ATOM   2347 C CA    . VAL A 1 313 ? -23.699 20.045  -50.220 1.000 27.382  0 312  VAL A CA    1 ? 
ATOM   2348 C C     . VAL A 1 313 ? -24.040 20.766  -48.936 1.000 27.477  0 312  VAL A C     1 ? 
ATOM   2349 O O     . VAL A 1 313 ? -23.150 21.209  -48.240 1.000 24.098  0 312  VAL A O     1 ? 
ATOM   2350 C CB    . VAL A 1 313 ? -22.918 18.754  -49.922 1.000 28.884  0 312  VAL A CB    1 ? 
ATOM   2351 C CG1   . VAL A 1 313 ? -23.692 17.834  -48.996 1.000 29.074  0 312  VAL A CG1   1 ? 
ATOM   2352 C CG2   . VAL A 1 313 ? -22.528 18.021  -51.203 1.000 30.743  0 312  VAL A CG2   1 ? 
ATOM   2353 N N     . ASP A 1 314 ? -25.333 20.917  -48.680 1.000 24.929  0 313  ASP A N     1 ? 
ATOM   2354 C CA    . ASP A 1 314 ? -25.811 21.509  -47.454 1.000 28.710  0 313  ASP A CA    1 ? 
ATOM   2355 C C     . ASP A 1 314 ? -25.747 20.456  -46.353 1.000 30.676  0 313  ASP A C     1 ? 
ATOM   2356 O O     . ASP A 1 314 ? -26.550 19.529  -46.283 1.000 31.095  0 313  ASP A O     1 ? 
ATOM   2357 C CB    . ASP A 1 314 ? -27.206 22.089  -47.651 1.000 32.499  0 313  ASP A CB    1 ? 
ATOM   2358 C CG    . ASP A 1 314 ? -27.740 22.853  -46.448 1.000 37.030  0 313  ASP A CG    1 ? 
ATOM   2359 O OD1   . ASP A 1 314 ? -26.917 23.222  -45.541 1.000 30.422  0 313  ASP A OD1   1 ? 
ATOM   2360 O OD2   . ASP A 1 314 ? -28.969 23.095  -46.442 1.000 38.206  0 313  ASP A OD2   1 ? 
ATOM   2361 N N     . ASN A 1 315 ? -24.744 20.605  -45.493 1.000 26.830  0 314  ASN A N     1 ? 
ATOM   2362 C CA    . ASN A 1 315 ? -24.486 19.679  -44.418 1.000 23.938  0 314  ASN A CA    1 ? 
ATOM   2363 C C     . ASN A 1 315 ? -24.287 20.541  -43.181 1.000 24.296  0 314  ASN A C     1 ? 
ATOM   2364 O O     . ASN A 1 315 ? -23.159 20.949  -42.895 1.000 25.834  0 314  ASN A O     1 ? 
ATOM   2365 C CB    . ASN A 1 315 ? -23.294 18.809  -44.808 1.000 25.031  0 314  ASN A CB    1 ? 
ATOM   2366 C CG    . ASN A 1 315 ? -23.017 17.733  -43.797 1.000 23.466  0 314  ASN A CG    1 ? 
ATOM   2367 O OD1   . ASN A 1 315 ? -23.381 17.887  -42.630 1.000 22.992  0 314  ASN A OD1   1 ? 
ATOM   2368 N ND2   . ASN A 1 315 ? -22.355 16.668  -44.232 1.000 26.342  0 314  ASN A ND2   1 ? 
ATOM   2369 N N     . PRO A 1 316 ? -25.375 20.925  -42.493 1.000 27.263  0 315  PRO A N     1 ? 
ATOM   2370 C CA    . PRO A 1 316 ? -25.282 21.970  -41.468 1.000 27.277  0 315  PRO A CA    1 ? 
ATOM   2371 C C     . PRO A 1 316 ? -24.491 21.641  -40.195 1.000 26.974  0 315  PRO A C     1 ? 
ATOM   2372 O O     . PRO A 1 316 ? -24.165 22.552  -39.424 1.000 24.484  0 315  PRO A O     1 ? 
ATOM   2373 C CB    . PRO A 1 316 ? -26.758 22.284  -41.169 1.000 29.432  0 315  PRO A CB    1 ? 
ATOM   2374 C CG    . PRO A 1 316 ? -27.481 21.029  -41.535 1.000 32.087  0 315  PRO A CG    1 ? 
ATOM   2375 C CD    . PRO A 1 316 ? -26.750 20.438  -42.714 1.000 28.902  0 315  PRO A CD    1 ? 
ATOM   2376 N N     . ALA A 1 317 ? -24.146 20.372  -39.980 1.000 23.269  0 316  ALA A N     1 ? 
ATOM   2377 C CA    . ALA A 1 317 ? -23.432 19.973  -38.773 1.000 21.476  0 316  ALA A CA    1 ? 
ATOM   2378 C C     . ALA A 1 317 ? -21.930 20.263  -38.869 1.000 20.772  0 316  ALA A C     1 ? 
ATOM   2379 O O     . ALA A 1 317 ? -21.232 20.169  -37.862 1.000 20.122  0 316  ALA A O     1 ? 
ATOM   2380 C CB    . ALA A 1 317 ? -23.642 18.509  -38.463 1.000 20.644  0 316  ALA A CB    1 ? 
ATOM   2381 N N     . VAL A 1 318 ? -21.428 20.544  -40.075 1.000 20.483  0 317  VAL A N     1 ? 
ATOM   2382 C CA    . VAL A 1 318 ? -20.000 20.735  -40.283 1.000 19.494  0 317  VAL A CA    1 ? 
ATOM   2383 C C     . VAL A 1 318 ? -19.523 21.957  -39.489 1.000 22.015  0 317  VAL A C     1 ? 
ATOM   2384 O O     . VAL A 1 318 ? -19.934 23.083  -39.770 1.000 21.284  0 317  VAL A O     1 ? 
ATOM   2385 C CB    . VAL A 1 318 ? -19.601 20.840  -41.759 1.000 19.853  0 317  VAL A CB    1 ? 
ATOM   2386 C CG1   . VAL A 1 318 ? -18.106 21.113  -41.875 1.000 20.261  0 317  VAL A CG1   1 ? 
ATOM   2387 C CG2   . VAL A 1 318 ? -19.971 19.567  -42.525 1.000 20.626  0 317  VAL A CG2   1 ? 
ATOM   2388 N N     . GLY A 1 319 ? -18.584 21.706  -38.550 1.000 19.590  0 318  GLY A N     1 ? 
ATOM   2389 C CA    . GLY A 1 319 ? -18.002 22.738  -37.702 1.000 20.640  0 318  GLY A CA    1 ? 
ATOM   2390 C C     . GLY A 1 319 ? -18.832 23.055  -36.466 1.000 19.710  0 318  GLY A C     1 ? 
ATOM   2391 O O     . GLY A 1 319 ? -18.445 23.877  -35.636 1.000 22.691  0 318  GLY A O     1 ? 
ATOM   2392 N N     . LYS A 1 320 ? -20.002 22.442  -36.350 1.000 21.629  0 319  LYS A N     1 ? 
ATOM   2393 C CA    . LYS A 1 320 ? -20.819 22.651  -35.169 1.000 20.752  0 319  LYS A CA    1 ? 
ATOM   2394 C C     . LYS A 1 320 ? -20.515 21.566  -34.142 1.000 20.725  0 319  LYS A C     1 ? 
ATOM   2395 O O     . LYS A 1 320 ? -19.836 20.581  -34.436 1.000 21.539  0 319  LYS A O     1 ? 
ATOM   2396 C CB    . LYS A 1 320 ? -22.306 22.591  -35.525 1.000 22.495  0 319  LYS A CB    1 ? 
ATOM   2397 C CG    . LYS A 1 320 ? -22.729 23.555  -36.620 1.000 28.406  0 319  LYS A CG    1 ? 
ATOM   2398 C CD    . LYS A 1 320 ? -22.305 24.991  -36.400 1.000 34.992  0 319  LYS A CD    1 ? 
ATOM   2399 C CE    . LYS A 1 320 ? -22.638 25.783  -37.647 1.000 45.566  0 319  LYS A CE    1 ? 
ATOM   2400 N NZ    . LYS A 1 320 ? -22.402 27.205  -37.396 1.000 48.143  0 319  LYS A NZ    1 ? 
ATOM   2401 N N     . HIS A 1 321 ? -21.077 21.755  -32.948 1.000 20.163  0 320  HIS A N     1 ? 
ATOM   2402 C CA    . HIS A 1 321 ? -20.976 20.780  -31.870 1.000 20.772  0 320  HIS A CA    1 ? 
ATOM   2403 C C     . HIS A 1 321 ? -19.523 20.596  -31.428 1.000 19.838  0 320  HIS A C     1 ? 
ATOM   2404 O O     . HIS A 1 321 ? -19.157 19.504  -31.001 1.000 21.098  0 320  HIS A O     1 ? 
ATOM   2405 C CB    . HIS A 1 321 ? -21.543 19.422  -32.293 1.000 21.696  0 320  HIS A CB    1 ? 
ATOM   2406 C CG    . HIS A 1 321 ? -22.892 19.530  -32.891 1.000 21.795  0 320  HIS A CG    1 ? 
ATOM   2407 N ND1   . HIS A 1 321 ? -23.942 20.061  -32.163 1.000 25.110  0 320  HIS A ND1   1 ? 
ATOM   2408 C CD2   . HIS A 1 321 ? -23.354 19.305  -34.140 1.000 23.121  0 320  HIS A CD2   1 ? 
ATOM   2409 C CE1   . HIS A 1 321 ? -25.036 20.088  -32.936 1.000 24.424  0 320  HIS A CE1   1 ? 
ATOM   2410 N NE2   . HIS A 1 321 ? -24.701 19.658  -34.153 1.000 24.323  0 320  HIS A NE2   1 ? 
ATOM   2411 N N     . LEU A 1 322 ? -18.692 21.639  -31.542 1.000 19.316  0 321  LEU A N     1 ? 
ATOM   2412 C CA    . LEU A 1 322 ? -17.337 21.563  -31.027 1.000 19.539  0 321  LEU A CA    1 ? 
ATOM   2413 C C     . LEU A 1 322 ? -17.390 21.356  -29.513 1.000 21.193  0 321  LEU A C     1 ? 
ATOM   2414 O O     . LEU A 1 322 ? -17.986 22.181  -28.817 1.000 20.481  0 321  LEU A O     1 ? 
ATOM   2415 C CB    . LEU A 1 322 ? -16.596 22.859  -31.308 1.000 19.783  0 321  LEU A CB    1 ? 
ATOM   2416 C CG    . LEU A 1 322 ? -15.208 22.990  -30.677 1.000 19.690  0 321  LEU A CG    1 ? 
ATOM   2417 C CD1   . LEU A 1 322 ? -14.251 21.922  -31.168 1.000 19.489  0 321  LEU A CD1   1 ? 
ATOM   2418 C CD2   . LEU A 1 322 ? -14.636 24.331  -30.988 1.000 21.102  0 321  LEU A CD2   1 ? 
ATOM   2419 N N     . LYS A 1 323 ? -16.719 20.303  -29.028 1.000 18.871  0 322  LYS A N     1 ? 
ATOM   2420 C CA    . LYS A 1 323 ? -16.615 20.013  -27.604 1.000 18.499  0 322  LYS A CA    1 ? 
ATOM   2421 C C     . LYS A 1 323 ? -15.141 20.054  -27.238 1.000 18.183  0 322  LYS A C     1 ? 
ATOM   2422 O O     . LYS A 1 323 ? -14.292 19.799  -28.086 1.000 18.164  0 322  LYS A O     1 ? 
ATOM   2423 C CB    . LYS A 1 323 ? -17.119 18.600  -27.318 1.000 19.681  0 322  LYS A CB    1 ? 
ATOM   2424 C CG    . LYS A 1 323 ? -18.570 18.306  -27.698 1.000 22.195  0 322  LYS A CG    1 ? 
ATOM   2425 C CD    . LYS A 1 323 ? -19.563 18.993  -26.803 1.000 25.484  0 322  LYS A CD    1 ? 
ATOM   2426 C CE    . LYS A 1 323 ? -19.472 18.567  -25.357 1.000 27.796  0 322  LYS A CE    1 ? 
ATOM   2427 N NZ    . LYS A 1 323 ? -20.587 19.183  -24.637 1.000 26.732  0 322  LYS A NZ    1 ? 
ATOM   2428 N N     . ASP A 1 324 ? -14.842 20.400  -25.985 1.000 17.603  0 323  ASP A N     1 ? 
ATOM   2429 C CA    . ASP A 1 324 ? -13.466 20.384  -25.512 1.000 18.327  0 323  ASP A CA    1 ? 
ATOM   2430 C C     . ASP A 1 324 ? -13.539 20.230  -24.003 1.000 17.521  0 323  ASP A C     1 ? 
ATOM   2431 O O     . ASP A 1 324 ? -14.626 20.371  -23.454 1.000 19.298  0 323  ASP A O     1 ? 
ATOM   2432 C CB    . ASP A 1 324 ? -12.725 21.652  -25.875 1.000 16.894  0 323  ASP A CB    1 ? 
ATOM   2433 C CG    . ASP A 1 324 ? -11.206 21.545  -25.935 1.000 18.745  0 323  ASP A CG    1 ? 
ATOM   2434 O OD1   . ASP A 1 324 ? -10.636 20.524  -25.477 1.000 19.196  0 323  ASP A OD1   1 ? 
ATOM   2435 O OD2   . ASP A 1 324 ? -10.634 22.488  -26.446 1.000 22.708  0 323  ASP A OD2   1 ? 
ATOM   2436 N N     . HIS A 1 325 ? -12.411 19.898  -23.381 1.000 17.971  0 324  HIS A N     1 ? 
ATOM   2437 C CA    . HIS A 1 325 ? -12.333 19.746  -21.930 1.000 19.216  0 324  HIS A CA    1 ? 
ATOM   2438 C C     . HIS A 1 325 ? -11.692 20.994  -21.325 1.000 18.203  0 324  HIS A C     1 ? 
ATOM   2439 O O     . HIS A 1 325 ? -10.574 21.335  -21.693 1.000 19.151  0 324  HIS A O     1 ? 
ATOM   2440 C CB    . HIS A 1 325 ? -11.480 18.531  -21.563 1.000 20.474  0 324  HIS A CB    1 ? 
ATOM   2441 C CG    . HIS A 1 325 ? -12.054 17.218  -21.916 1.000 18.449  0 324  HIS A CG    1 ? 
ATOM   2442 N ND1   . HIS A 1 325 ? -11.325 16.218  -22.535 1.000 18.722  0 324  HIS A ND1   1 ? 
ATOM   2443 C CD2   . HIS A 1 325 ? -13.302 16.775  -21.793 1.000 19.167  0 324  HIS A CD2   1 ? 
ATOM   2444 C CE1   . HIS A 1 325 ? -12.120 15.178  -22.699 1.000 19.885  0 324  HIS A CE1   1 ? 
ATOM   2445 N NE2   . HIS A 1 325 ? -13.333 15.508  -22.282 1.000 19.349  0 324  HIS A NE2   1 ? 
ATOM   2446 N N     . PRO A 1 326 ? -12.365 21.709  -20.396 1.000 17.093  0 325  PRO A N     1 ? 
ATOM   2447 C CA    . PRO A 1 326 ? -11.740 22.804  -19.647 1.000 18.815  0 325  PRO A CA    1 ? 
ATOM   2448 C C     . PRO A 1 326 ? -10.900 22.215  -18.525 1.000 19.130  0 325  PRO A C     1 ? 
ATOM   2449 O O     . PRO A 1 326 ? -11.283 21.204  -17.953 1.000 18.681  0 325  PRO A O     1 ? 
ATOM   2450 C CB    . PRO A 1 326 ? -12.943 23.586  -19.062 1.000 18.227  0 325  PRO A CB    1 ? 
ATOM   2451 C CG    . PRO A 1 326 ? -13.983 22.514  -18.868 1.000 16.721  0 325  PRO A CG    1 ? 
ATOM   2452 C CD    . PRO A 1 326 ? -13.759 21.491  -19.977 1.000 16.128  0 325  PRO A CD    1 ? 
ATOM   2453 N N     . ILE A 1 327 ? -9.779  22.875  -18.226 1.000 19.294  0 326  ILE A N     1 ? 
ATOM   2454 C CA    . ILE A 1 327 ? -8.873  22.469  -17.167 1.000 17.622  0 326  ILE A CA    1 ? 
ATOM   2455 C C     . ILE A 1 327 ? -8.446  23.710  -16.396 1.000 18.333  0 326  ILE A C     1 ? 
ATOM   2456 O O     . ILE A 1 327 ? -8.277  24.783  -16.990 1.000 17.749  0 326  ILE A O     1 ? 
ATOM   2457 C CB    . ILE A 1 327 ? -7.655  21.722  -17.750 1.000 17.597  0 326  ILE A CB    1 ? 
ATOM   2458 C CG1   . ILE A 1 327 ? -6.680  21.266  -16.676 1.000 19.163  0 326  ILE A CG1   1 ? 
ATOM   2459 C CG2   . ILE A 1 327 ? -6.943  22.564  -18.795 1.000 20.260  0 326  ILE A CG2   1 ? 
ATOM   2460 C CD1   . ILE A 1 327 ? -5.696  20.229  -17.215 1.000 21.403  0 326  ILE A CD1   1 ? 
ATOM   2461 N N     . MET A 1 328 ? -8.288  23.575  -15.060 1.000 16.682  0 327  MET A N     1 ? 
ATOM   2462 C CA    . MET A 1 328 ? -7.618  24.600  -14.285 1.000 19.332  0 327  MET A CA    1 ? 
ATOM   2463 C C     . MET A 1 328 ? -6.729  23.941  -13.235 1.000 20.414  0 327  MET A C     1 ? 
ATOM   2464 O O     . MET A 1 328 ? -7.091  22.913  -12.674 1.000 19.949  0 327  MET A O     1 ? 
ATOM   2465 C CB    . MET A 1 328 ? -8.630  25.581  -13.660 1.000 21.368  0 327  MET A CB    1 ? 
ATOM   2466 C CG    . MET A 1 328 ? -9.525  25.009  -12.606 1.000 22.049  0 327  MET A CG    1 ? 
ATOM   2467 S SD    . MET A 1 328 ? -10.827 26.195  -12.181 1.000 23.764  0 327  MET A SD    1 ? 
ATOM   2468 C CE    . MET A 1 328 ? -11.343 25.548  -10.584 1.000 22.124  0 327  MET A CE    1 ? 
ATOM   2469 N N     . ALA A 1 329 ? -5.555  24.535  -12.997 1.000 17.620  0 328  ALA A N     1 ? 
ATOM   2470 C CA    . ALA A 1 329 ? -4.591  23.938  -12.088 1.000 19.027  0 328  ALA A CA    1 ? 
ATOM   2471 C C     . ALA A 1 329 ? -4.914  24.335  -10.645 1.000 18.568  0 328  ALA A C     1 ? 
ATOM   2472 O O     . ALA A 1 329 ? -5.319  25.463  -10.390 1.000 18.356  0 328  ALA A O     1 ? 
ATOM   2473 C CB    . ALA A 1 329 ? -3.212  24.428  -12.474 1.000 21.109  0 328  ALA A CB    1 ? 
ATOM   2474 N N     . ASN A 1 330 ? -4.696  23.394  -9.725  1.000 16.246  0 329  ASN A N     1 ? 
ATOM   2475 C CA    . ASN A 1 330 ? -4.619  23.616  -8.282  1.000 17.700  0 329  ASN A CA    1 ? 
ATOM   2476 C C     . ASN A 1 330 ? -3.184  23.353  -7.837  1.000 18.338  0 329  ASN A C     1 ? 
ATOM   2477 O O     . ASN A 1 330 ? -2.740  22.208  -7.848  1.000 17.461  0 329  ASN A O     1 ? 
ATOM   2478 C CB    . ASN A 1 330 ? -5.560  22.706  -7.516  1.000 18.872  0 329  ASN A CB    1 ? 
ATOM   2479 C CG    . ASN A 1 330 ? -6.995  22.930  -7.927  1.000 20.496  0 329  ASN A CG    1 ? 
ATOM   2480 O OD1   . ASN A 1 330 ? -7.711  23.742  -7.325  1.000 21.021  0 329  ASN A OD1   1 ? 
ATOM   2481 N ND2   . ASN A 1 330 ? -7.427  22.250  -8.980  1.000 20.041  0 329  ASN A ND2   1 ? 
ATOM   2482 N N     . TYR A 1 331 ? -2.429  24.438  -7.582  1.000 17.648  0 330  TYR A N     1 ? 
ATOM   2483 C CA    . TYR A 1 331 ? -1.023  24.316  -7.268  1.000 17.535  0 330  TYR A CA    1 ? 
ATOM   2484 C C     . TYR A 1 331 ? -0.847  24.229  -5.756  1.000 17.338  0 330  TYR A C     1 ? 
ATOM   2485 O O     . TYR A 1 331 ? -1.478  24.978  -5.032  1.000 18.795  0 330  TYR A O     1 ? 
ATOM   2486 C CB    . TYR A 1 331 ? -0.169  25.479  -7.761  1.000 17.601  0 330  TYR A CB    1 ? 
ATOM   2487 C CG    . TYR A 1 331 ? -0.202  25.646  -9.276  1.000 16.582  0 330  TYR A CG    1 ? 
ATOM   2488 C CD1   . TYR A 1 331 ? 0.336   24.671  -10.096 1.000 17.264  0 330  TYR A CD1   1 ? 
ATOM   2489 C CD2   . TYR A 1 331 ? -0.771  26.759  -9.872  1.000 19.593  0 330  TYR A CD2   1 ? 
ATOM   2490 C CE1   . TYR A 1 331 ? 0.296   24.794  -11.474 1.000 15.804  0 330  TYR A CE1   1 ? 
ATOM   2491 C CE2   . TYR A 1 331 ? -0.824  26.890  -11.255 1.000 16.847  0 330  TYR A CE2   1 ? 
ATOM   2492 C CZ    . TYR A 1 331 ? -0.257  25.921  -12.046 1.000 17.153  0 330  TYR A CZ    1 ? 
ATOM   2493 O OH    . TYR A 1 331 ? -0.273  26.067  -13.401 1.000 15.763  0 330  TYR A OH    1 ? 
ATOM   2494 N N     . PHE A 1 332 ? 0.107   23.387  -5.349  1.000 19.314  0 331  PHE A N     1 ? 
ATOM   2495 C CA    . PHE A 1 332 ? 0.453   23.230  -3.952  1.000 19.535  0 331  PHE A CA    1 ? 
ATOM   2496 C C     . PHE A 1 332 ? 1.964   23.281  -3.811  1.000 20.698  0 331  PHE A C     1 ? 
ATOM   2497 O O     . PHE A 1 332 ? 2.695   22.642  -4.536  1.000 19.576  0 331  PHE A O     1 ? 
ATOM   2498 C CB    . PHE A 1 332 ? -0.114  21.910  -3.452  1.000 19.579  0 331  PHE A CB    1 ? 
ATOM   2499 C CG    . PHE A 1 332 ? -1.622  21.764  -3.539  1.000 19.118  0 331  PHE A CG    1 ? 
ATOM   2500 C CD1   . PHE A 1 332 ? -2.212  21.191  -4.664  1.000 19.286  0 331  PHE A CD1   1 ? 
ATOM   2501 C CD2   . PHE A 1 332 ? -2.433  22.146  -2.483  1.000 20.237  0 331  PHE A CD2   1 ? 
ATOM   2502 C CE1   . PHE A 1 332 ? -3.586  20.982  -4.701  1.000 20.120  0 331  PHE A CE1   1 ? 
ATOM   2503 C CE2   . PHE A 1 332 ? -3.793  21.940  -2.520  1.000 19.876  0 331  PHE A CE2   1 ? 
ATOM   2504 C CZ    . PHE A 1 332 ? -4.378  21.403  -3.651  1.000 21.972  0 331  PHE A CZ    1 ? 
ATOM   2505 N N     . GLN A 1 333 ? 2.426   24.045  -2.840  1.000 22.159  0 332  GLN A N     1 ? 
ATOM   2506 C CA    . GLN A 1 333 ? 3.829   23.983  -2.485  1.000 24.150  0 332  GLN A CA    1 ? 
ATOM   2507 C C     . GLN A 1 333 ? 4.028   22.732  -1.641  1.000 21.587  0 332  GLN A C     1 ? 
ATOM   2508 O O     . GLN A 1 333 ? 3.205   22.441  -0.771  1.000 22.131  0 332  GLN A O     1 ? 
ATOM   2509 C CB    . GLN A 1 333 ? 4.194   25.276  -1.762  1.000 28.306  0 332  GLN A CB    1 ? 
ATOM   2510 C CG    . GLN A 1 333 ? 5.672   25.368  -1.411  1.000 31.093  0 332  GLN A CG    1 ? 
ATOM   2511 C CD    . GLN A 1 333 ? 6.168   26.799  -1.355  1.000 41.648  0 332  GLN A CD    1 ? 
ATOM   2512 O OE1   . GLN A 1 333 ? 5.421   27.756  -1.600  1.000 46.815  0 332  GLN A OE1   1 ? 
ATOM   2513 N NE2   . GLN A 1 333 ? 7.454   26.954  -1.080  1.000 43.365  0 332  GLN A NE2   1 ? 
ATOM   2514 N N     . VAL A 1 334 ? 5.135   22.027  -1.886  1.000 20.323  0 333  VAL A N     1 ? 
ATOM   2515 C CA    . VAL A 1 334 ? 5.372   20.747  -1.251  1.000 20.627  0 333  VAL A CA    1 ? 
ATOM   2516 C C     . VAL A 1 334 ? 6.729   20.743  -0.570  1.000 25.746  0 333  VAL A C     1 ? 
ATOM   2517 O O     . VAL A 1 334 ? 7.640   21.479  -0.942  1.000 21.466  0 333  VAL A O     1 ? 
ATOM   2518 C CB    . VAL A 1 334 ? 5.238   19.521  -2.175  1.000 22.072  0 333  VAL A CB    1 ? 
ATOM   2519 C CG1   . VAL A 1 334 ? 3.824   19.429  -2.722  1.000 21.952  0 333  VAL A CG1   1 ? 
ATOM   2520 C CG2   . VAL A 1 334 ? 6.258   19.520  -3.305  1.000 21.669  0 333  VAL A CG2   1 ? 
ATOM   2521 N N     . ASN A 1 335 ? 6.776   19.920  0.505   1.000 27.155  0 334  ASN A N     1 ? 
ATOM   2522 C CA    . ASN A 1 335 ? 7.876   19.822  1.445   1.000 26.291  0 334  ASN A CA    1 ? 
ATOM   2523 C C     . ASN A 1 335 ? 8.716   18.676  0.905   1.000 27.375  0 334  ASN A C     1 ? 
ATOM   2524 O O     . ASN A 1 335 ? 8.687   17.566  1.426   1.000 27.426  0 334  ASN A O     1 ? 
ATOM   2525 C CB    . ASN A 1 335 ? 7.282   19.644  2.847   1.000 28.542  0 334  ASN A CB    1 ? 
ATOM   2526 C CG    . ASN A 1 335 ? 8.281   19.254  3.901   1.000 30.515  0 334  ASN A CG    1 ? 
ATOM   2527 O OD1   . ASN A 1 335 ? 9.410   19.766  3.892   1.000 27.637  0 334  ASN A OD1   1 ? 
ATOM   2528 N ND2   . ASN A 1 335 ? 7.857   18.384  4.825   1.000 31.414  0 334  ASN A ND2   1 ? 
ATOM   2529 N N     . SER A 1 336 ? 9.329   18.919  -0.248  1.000 24.583  0 335  SER A N     1 ? 
ATOM   2530 C CA    . SER A 1 336 ? 9.968   17.871  -1.005  1.000 23.682  0 335  SER A CA    1 ? 
ATOM   2531 C C     . SER A 1 336 ? 10.955  18.515  -1.952  1.000 25.320  0 335  SER A C     1 ? 
ATOM   2532 O O     . SER A 1 336 ? 10.706  19.618  -2.438  1.000 25.766  0 335  SER A O     1 ? 
ATOM   2533 C CB    . SER A 1 336 ? 8.960   17.059  -1.770  1.000 24.767  0 335  SER A CB    1 ? 
ATOM   2534 O OG    . SER A 1 336 ? 9.604   16.107  -2.602  1.000 22.876  0 335  SER A OG    1 ? 
ATOM   2535 N N     . ASN A 1 337 ? 12.039  17.796  -2.228  1.000 23.434  0 336  ASN A N     1 ? 
ATOM   2536 C CA    . ASN A 1 337 ? 12.992  18.195  -3.247  1.000 26.905  0 336  ASN A CA    1 ? 
ATOM   2537 C C     . ASN A 1 337 ? 13.004  17.167  -4.384  1.000 28.267  0 336  ASN A C     1 ? 
ATOM   2538 O O     . ASN A 1 337 ? 13.993  17.082  -5.098  1.000 26.112  0 336  ASN A O     1 ? 
ATOM   2539 C CB    . ASN A 1 337 ? 14.387  18.375  -2.638  1.000 30.321  0 336  ASN A CB    1 ? 
ATOM   2540 C CG    . ASN A 1 337 ? 14.460  19.565  -1.706  1.000 35.051  0 336  ASN A CG    1 ? 
ATOM   2541 O OD1   . ASN A 1 337 ? 14.761  19.441  -0.512  1.000 46.488  0 336  ASN A OD1   1 ? 
ATOM   2542 N ND2   . ASN A 1 337 ? 14.215  20.745  -2.236  1.000 35.909  0 336  ASN A ND2   1 ? 
ATOM   2543 N N     . GLU A 1 338 ? 11.924  16.375  -4.537  1.000 25.802  0 337  GLU A N     1 ? 
ATOM   2544 C CA    . GLU A 1 338 ? 11.857  15.297  -5.522  1.000 26.183  0 337  GLU A CA    1 ? 
ATOM   2545 C C     . GLU A 1 338 ? 10.923  15.651  -6.692  1.000 24.316  0 337  GLU A C     1 ? 
ATOM   2546 O O     . GLU A 1 338 ? 10.484  14.762  -7.433  1.000 20.282  0 337  GLU A O     1 ? 
ATOM   2547 C CB    . GLU A 1 338 ? 11.341  14.017  -4.843  1.000 28.437  0 337  GLU A CB    1 ? 
ATOM   2548 C CG    . GLU A 1 338 ? 12.290  13.340  -3.845  1.000 34.032  0 337  GLU A CG    1 ? 
ATOM   2549 C CD    . GLU A 1 338 ? 11.844  11.997  -3.217  1.000 42.197  0 337  GLU A CD    1 ? 
ATOM   2550 O OE1   . GLU A 1 338 ? 10.752  11.826  -2.605  1.000 36.437  0 337  GLU A OE1   1 ? 
ATOM   2551 O OE2   . GLU A 1 338 ? 12.670  11.058  -3.281  1.000 53.303  0 337  GLU A OE2   1 ? 
ATOM   2552 N N     . THR A 1 339 ? 10.571  16.934  -6.866  1.000 21.057  0 338  THR A N     1 ? 
ATOM   2553 C CA    . THR A 1 339 ? 9.686   17.321  -7.960  1.000 21.493  0 338  THR A CA    1 ? 
ATOM   2554 C C     . THR A 1 339 ? 10.513  17.539  -9.212  1.000 22.323  0 338  THR A C     1 ? 
ATOM   2555 O O     . THR A 1 339 ? 11.749  17.544  -9.140  1.000 20.368  0 338  THR A O     1 ? 
ATOM   2556 C CB    . THR A 1 339 ? 8.862   18.567  -7.614  1.000 19.688  0 338  THR A CB    1 ? 
ATOM   2557 O OG1   . THR A 1 339 ? 9.691   19.737  -7.656  1.000 19.091  0 338  THR A OG1   1 ? 
ATOM   2558 C CG2   . THR A 1 339 ? 8.169   18.447  -6.270  1.000 18.998  0 338  THR A CG2   1 ? 
ATOM   2559 N N     . TYR A 1 340 ? 9.837   17.756  -10.357 1.000 19.325  0 339  TYR A N     1 ? 
ATOM   2560 C CA    . TYR A 1 340 ? 10.534  18.053  -11.600 1.000 20.577  0 339  TYR A CA    1 ? 
ATOM   2561 C C     . TYR A 1 340 ? 10.659  19.551  -11.907 1.000 18.711  0 339  TYR A C     1 ? 
ATOM   2562 O O     . TYR A 1 340 ? 10.920  19.943  -13.056 1.000 20.660  0 339  TYR A O     1 ? 
ATOM   2563 C CB    . TYR A 1 340 ? 9.789   17.354  -12.747 1.000 20.546  0 339  TYR A CB    1 ? 
ATOM   2564 C CG    . TYR A 1 340 ? 9.762   15.829  -12.641 1.000 20.750  0 339  TYR A CG    1 ? 
ATOM   2565 C CD1   . TYR A 1 340 ? 10.872  15.118  -12.214 1.000 22.794  0 339  TYR A CD1   1 ? 
ATOM   2566 C CD2   . TYR A 1 340 ? 8.616   15.089  -12.975 1.000 23.853  0 339  TYR A CD2   1 ? 
ATOM   2567 C CE1   . TYR A 1 340 ? 10.870  13.729  -12.157 1.000 22.854  0 339  TYR A CE1   1 ? 
ATOM   2568 C CE2   . TYR A 1 340 ? 8.594   13.704  -12.911 1.000 24.729  0 339  TYR A CE2   1 ? 
ATOM   2569 C CZ    . TYR A 1 340 ? 9.728   13.023  -12.503 1.000 24.012  0 339  TYR A CZ    1 ? 
ATOM   2570 O OH    . TYR A 1 340 ? 9.672   11.653  -12.429 1.000 24.923  0 339  TYR A OH    1 ? 
ATOM   2571 N N     . ASP A 1 341 ? 10.476  20.407  -10.911 1.000 18.943  0 340  ASP A N     1 ? 
ATOM   2572 C CA    . ASP A 1 341 ? 10.431  21.837  -11.172 1.000 19.000  0 340  ASP A CA    1 ? 
ATOM   2573 C C     . ASP A 1 341 ? 11.787  22.377  -11.648 1.000 23.599  0 340  ASP A C     1 ? 
ATOM   2574 O O     . ASP A 1 341 ? 11.850  23.289  -12.474 1.000 21.313  0 340  ASP A O     1 ? 
ATOM   2575 C CB    . ASP A 1 341 ? 9.994   22.570  -9.920  1.000 20.786  0 340  ASP A CB    1 ? 
ATOM   2576 C CG    . ASP A 1 341 ? 8.524   22.316  -9.610  1.000 20.128  0 340  ASP A CG    1 ? 
ATOM   2577 O OD1   . ASP A 1 341 ? 7.702   22.745  -10.436 1.000 21.394  0 340  ASP A OD1   1 ? 
ATOM   2578 O OD2   . ASP A 1 341 ? 8.226   21.686  -8.559  1.000 21.468  0 340  ASP A OD2   1 ? 
ATOM   2579 N N     . ASP A 1 342 ? 12.882  21.830  -11.119 1.000 23.745  0 341  ASP A N     1 ? 
ATOM   2580 C CA    . ASP A 1 342 ? 14.205  22.299  -11.535 1.000 25.748  0 341  ASP A CA    1 ? 
ATOM   2581 C C     . ASP A 1 342 ? 14.469  22.002  -12.997 1.000 25.480  0 341  ASP A C     1 ? 
ATOM   2582 O O     . ASP A 1 342 ? 15.123  22.775  -13.701 1.000 25.860  0 341  ASP A O     1 ? 
ATOM   2583 C CB    . ASP A 1 342 ? 15.290  21.732  -10.643 1.000 26.276  0 341  ASP A CB    1 ? 
ATOM   2584 C CG    . ASP A 1 342 ? 15.384  22.415  -9.297  1.000 33.898  0 341  ASP A CG    1 ? 
ATOM   2585 O OD1   . ASP A 1 342 ? 14.753  23.492  -9.136  1.000 32.343  0 341  ASP A OD1   1 ? 
ATOM   2586 O OD2   . ASP A 1 342 ? 16.036  21.843  -8.407  1.000 41.437  0 341  ASP A OD2   1 ? 
ATOM   2587 N N     . ILE A 1 343 ? 13.968  20.856  -13.463 1.000 23.331  0 342  ILE A N     1 ? 
ATOM   2588 C CA    . ILE A 1 343 ? 14.083  20.498  -14.867 1.000 22.839  0 342  ILE A CA    1 ? 
ATOM   2589 C C     . ILE A 1 343 ? 13.380  21.507  -15.755 1.000 25.364  0 342  ILE A C     1 ? 
ATOM   2590 O O     . ILE A 1 343 ? 13.894  21.858  -16.812 1.000 24.816  0 342  ILE A O     1 ? 
ATOM   2591 C CB    . ILE A 1 343 ? 13.564  19.066  -15.085 1.000 26.607  0 342  ILE A CB    1 ? 
ATOM   2592 C CG1   . ILE A 1 343 ? 14.382  18.069  -14.252 1.000 26.938  0 342  ILE A CG1   1 ? 
ATOM   2593 C CG2   . ILE A 1 343 ? 13.529  18.741  -16.578 1.000 26.495  0 342  ILE A CG2   1 ? 
ATOM   2594 C CD1   . ILE A 1 343 ? 13.802  16.659  -14.120 1.000 28.512  0 342  ILE A CD1   1 ? 
ATOM   2595 N N     . PHE A 1 344 ? 12.178  21.949  -15.365 1.000 24.169  0 343  PHE A N     1 ? 
ATOM   2596 C CA    . PHE A 1 344 ? 11.437  22.930  -16.147 1.000 23.525  0 343  PHE A CA    1 ? 
ATOM   2597 C C     . PHE A 1 344 ? 12.171  24.270  -16.173 1.000 22.466  0 343  PHE A C     1 ? 
ATOM   2598 O O     . PHE A 1 344 ? 12.250  24.921  -17.221 1.000 21.646  0 343  PHE A O     1 ? 
ATOM   2599 C CB    . PHE A 1 344 ? 10.015  23.112  -15.572 1.000 22.719  0 343  PHE A CB    1 ? 
ATOM   2600 C CG    . PHE A 1 344 ? 9.223   24.114  -16.394 1.000 24.668  0 343  PHE A CG    1 ? 
ATOM   2601 C CD1   . PHE A 1 344 ? 8.661   23.724  -17.600 1.000 26.849  0 343  PHE A CD1   1 ? 
ATOM   2602 C CD2   . PHE A 1 344 ? 9.165   25.454  -16.049 1.000 22.478  0 343  PHE A CD2   1 ? 
ATOM   2603 C CE1   . PHE A 1 344 ? 8.001   24.638  -18.400 1.000 29.969  0 343  PHE A CE1   1 ? 
ATOM   2604 C CE2   . PHE A 1 344 ? 8.506   26.359  -16.846 1.000 26.265  0 343  PHE A CE2   1 ? 
ATOM   2605 C CZ    . PHE A 1 344 ? 7.935   25.953  -18.037 1.000 28.045  0 343  PHE A CZ    1 ? 
ATOM   2606 N N     . ARG A 1 345 ? 12.638  24.692  -14.991 1.000 20.818  0 344  ARG A N     1 ? 
ATOM   2607 C CA    . ARG A 1 345 ? 13.177  26.023  -14.793 1.000 22.097  0 344  ARG A CA    1 ? 
ATOM   2608 C C     . ARG A 1 345 ? 14.609  26.178  -15.301 1.000 24.705  0 344  ARG A C     1 ? 
ATOM   2609 O O     . ARG A 1 345 ? 14.986  27.293  -15.607 1.000 25.948  0 344  ARG A O     1 ? 
ATOM   2610 C CB    . ARG A 1 345 ? 13.217  26.432  -13.322 1.000 20.891  0 344  ARG A CB    1 ? 
ATOM   2611 C CG    . ARG A 1 345 ? 11.799  26.581  -12.791 1.000 21.426  0 344  ARG A CG    1 ? 
ATOM   2612 C CD    . ARG A 1 345 ? 11.758  27.075  -11.362 1.000 23.048  0 344  ARG A CD    1 ? 
ATOM   2613 N NE    . ARG A 1 345 ? 12.280  26.134  -10.365 1.000 23.791  0 344  ARG A NE    1 ? 
ATOM   2614 C CZ    . ARG A 1 345 ? 11.764  25.891  -9.184  1.000 22.515  0 344  ARG A CZ    1 ? 
ATOM   2615 N NH1   . ARG A 1 345 ? 10.595  26.383  -8.812  1.000 22.295  0 344  ARG A NH1   1 ? 
ATOM   2616 N NH2   . ARG A 1 345 ? 12.393  25.066  -8.390  1.000 22.793  0 344  ARG A NH2   1 ? 
ATOM   2617 N N     . ASP A 1 346 ? 15.416  25.118  -15.290 1.000 22.584  0 345  ASP A N     1 ? 
ATOM   2618 C CA    . ASP A 1 346 ? 16.849  25.230  -15.538 1.000 25.213  0 345  ASP A CA    1 ? 
ATOM   2619 C C     . ASP A 1 346 ? 17.259  24.376  -16.737 1.000 25.858  0 345  ASP A C     1 ? 
ATOM   2620 O O     . ASP A 1 346 ? 17.289  23.149  -16.668 1.000 24.481  0 345  ASP A O     1 ? 
ATOM   2621 C CB    . ASP A 1 346 ? 17.587  24.892  -14.262 1.000 29.489  0 345  ASP A CB    1 ? 
ATOM   2622 C CG    . ASP A 1 346 ? 19.096  25.093  -14.308 1.000 33.938  0 345  ASP A CG    1 ? 
ATOM   2623 O OD1   . ASP A 1 346 ? 19.640  25.106  -15.432 1.000 35.590  0 345  ASP A OD1   1 ? 
ATOM   2624 O OD2   . ASP A 1 346 ? 19.687  25.231  -13.206 1.000 37.661  0 345  ASP A OD2   1 ? 
ATOM   2625 N N     . ARG A 1 347 ? 17.606  25.040  -17.840 1.000 25.933  0 346  ARG A N     1 ? 
ATOM   2626 C CA    . ARG A 1 347 ? 17.937  24.355  -19.070 1.000 25.549  0 346  ARG A CA    1 ? 
ATOM   2627 C C     . ARG A 1 347 ? 19.174  23.468  -18.900 1.000 26.278  0 346  ARG A C     1 ? 
ATOM   2628 O O     . ARG A 1 347 ? 19.276  22.435  -19.558 1.000 26.403  0 346  ARG A O     1 ? 
ATOM   2629 C CB    . ARG A 1 347 ? 18.164  25.395  -20.167 1.000 27.950  0 346  ARG A CB    1 ? 
ATOM   2630 C CG    . ARG A 1 347 ? 18.431  24.823  -21.553 1.000 29.704  0 346  ARG A CG    1 ? 
ATOM   2631 C CD    . ARG A 1 347 ? 17.436  23.766  -22.070 1.000 31.273  0 346  ARG A CD    1 ? 
ATOM   2632 N NE    . ARG A 1 347 ? 16.102  24.345  -22.235 1.000 33.907  0 346  ARG A NE    1 ? 
ATOM   2633 C CZ    . ARG A 1 347 ? 14.989  23.682  -22.562 1.000 36.095  0 346  ARG A CZ    1 ? 
ATOM   2634 N NH1   . ARG A 1 347 ? 14.988  22.372  -22.684 1.000 30.468  0 346  ARG A NH1   1 ? 
ATOM   2635 N NH2   . ARG A 1 347 ? 13.872  24.363  -22.776 1.000 37.016  0 346  ARG A NH2   1 ? 
ATOM   2636 N N     . ASP A 1 348 ? 20.102  23.841  -18.018 1.000 25.815  0 347  ASP A N     1 ? 
ATOM   2637 C CA    . ASP A 1 348 ? 21.272  23.003  -17.801 1.000 29.131  0 347  ASP A CA    1 ? 
ATOM   2638 C C     . ASP A 1 348 ? 20.898  21.676  -17.130 1.000 26.583  0 347  ASP A C     1 ? 
ATOM   2639 O O     . ASP A 1 348 ? 21.432  20.627  -17.498 1.000 23.043  0 347  ASP A O     1 ? 
ATOM   2640 C CB    . ASP A 1 348 ? 22.340  23.717  -16.992 1.000 34.469  0 347  ASP A CB    1 ? 
ATOM   2641 C CG    . ASP A 1 348 ? 22.879  24.981  -17.641 1.000 37.874  0 347  ASP A CG    1 ? 
ATOM   2642 O OD1   . ASP A 1 348 ? 23.023  24.974  -18.873 1.000 40.869  0 347  ASP A OD1   1 ? 
ATOM   2643 O OD2   . ASP A 1 348 ? 23.163  25.944  -16.902 1.000 40.607  0 347  ASP A OD2   1 ? 
ATOM   2644 N N     . VAL A 1 349 ? 19.989  21.735  -16.150 1.000 25.246  0 348  VAL A N     1 ? 
ATOM   2645 C CA    . VAL A 1 349 ? 19.427  20.566  -15.499 1.000 23.529  0 348  VAL A CA    1 ? 
ATOM   2646 C C     . VAL A 1 349 ? 18.738  19.667  -16.532 1.000 23.336  0 348  VAL A C     1 ? 
ATOM   2647 O O     . VAL A 1 349 ? 19.056  18.481  -16.617 1.000 23.725  0 348  VAL A O     1 ? 
ATOM   2648 C CB    . VAL A 1 349 ? 18.472  20.935  -14.346 1.000 25.354  0 348  VAL A CB    1 ? 
ATOM   2649 C CG1   . VAL A 1 349 ? 17.815  19.698  -13.744 1.000 25.454  0 348  VAL A CG1   1 ? 
ATOM   2650 C CG2   . VAL A 1 349 ? 19.211  21.682  -13.227 1.000 27.091  0 348  VAL A CG2   1 ? 
ATOM   2651 N N     . SER A 1 350 ? 17.804  20.232  -17.300 1.000 21.504  0 349  SER A N     1 ? 
ATOM   2652 C CA    . SER A 1 350 ? 17.141  19.511  -18.377 1.000 22.018  0 349  SER A CA    1 ? 
ATOM   2653 C C     . SER A 1 350 ? 18.159  18.847  -19.311 1.000 22.068  0 349  SER A C     1 ? 
ATOM   2654 O O     . SER A 1 350 ? 18.021  17.683  -19.659 1.000 20.752  0 349  SER A O     1 ? 
ATOM   2655 C CB    . SER A 1 350 ? 16.196  20.430  -19.136 1.000 24.074  0 349  SER A CB    1 ? 
ATOM   2656 O OG    . SER A 1 350 ? 15.532  19.710  -20.169 1.000 25.969  0 349  SER A OG    1 ? 
ATOM   2657 N N     . ASN A 1 351 ? 19.164  19.600  -19.757 1.000 23.858  0 350  ASN A N     1 ? 
ATOM   2658 C CA    . ASN A 1 351 ? 20.146  19.084  -20.703 1.000 23.689  0 350  ASN A CA    1 ? 
ATOM   2659 C C     . ASN A 1 351 ? 20.946  17.927  -20.126 1.000 19.458  0 350  ASN A C     1 ? 
ATOM   2660 O O     . ASN A 1 351 ? 21.310  17.020  -20.856 1.000 23.358  0 350  ASN A O     1 ? 
ATOM   2661 C CB    . ASN A 1 351 ? 21.131  20.153  -21.173 1.000 25.908  0 350  ASN A CB    1 ? 
ATOM   2662 C CG    . ASN A 1 351 ? 20.538  21.092  -22.189 1.000 26.175  0 350  ASN A CG    1 ? 
ATOM   2663 O OD1   . ASN A 1 351 ? 19.519  20.799  -22.808 1.000 28.998  0 350  ASN A OD1   1 ? 
ATOM   2664 N ND2   . ASN A 1 351 ? 21.190  22.213  -22.412 1.000 28.171  0 350  ASN A ND2   1 ? 
ATOM   2665 N N     . THR A 1 352 ? 21.224  17.947  -18.835 1.000 21.014  0 351  THR A N     1 ? 
ATOM   2666 C CA    . THR A 1 352 ? 21.994  16.896  -18.203 1.000 21.815  0 351  THR A CA    1 ? 
ATOM   2667 C C     . THR A 1 352 ? 21.166  15.606  -18.133 1.000 21.297  0 351  THR A C     1 ? 
ATOM   2668 O O     . THR A 1 352 ? 21.667  14.508  -18.393 1.000 20.636  0 351  THR A O     1 ? 
ATOM   2669 C CB    . THR A 1 352 ? 22.439  17.406  -16.821 1.000 24.563  0 351  THR A CB    1 ? 
ATOM   2670 O OG1   . THR A 1 352 ? 23.307  18.531  -17.014 1.000 26.733  0 351  THR A OG1   1 ? 
ATOM   2671 C CG2   . THR A 1 352 ? 23.208  16.359  -16.057 1.000 22.806  0 351  THR A CG2   1 ? 
ATOM   2672 N N     . PHE A 1 353 ? 19.868  15.731  -17.800 1.000 19.717  0 352  PHE A N     1 ? 
ATOM   2673 C CA    . PHE A 1 353 ? 19.000  14.570  -17.813 1.000 18.319  0 352  PHE A CA    1 ? 
ATOM   2674 C C     . PHE A 1 353 ? 18.740  14.107  -19.247 1.000 18.738  0 352  PHE A C     1 ? 
ATOM   2675 O O     . PHE A 1 353 ? 18.583  12.901  -19.445 1.000 19.325  0 352  PHE A O     1 ? 
ATOM   2676 C CB    . PHE A 1 353 ? 17.680  14.864  -17.118 1.000 20.456  0 352  PHE A CB    1 ? 
ATOM   2677 C CG    . PHE A 1 353 ? 17.859  14.856  -15.620 1.000 21.056  0 352  PHE A CG    1 ? 
ATOM   2678 C CD1   . PHE A 1 353 ? 18.486  13.781  -14.990 1.000 23.074  0 352  PHE A CD1   1 ? 
ATOM   2679 C CD2   . PHE A 1 353 ? 17.436  15.932  -14.859 1.000 23.657  0 352  PHE A CD2   1 ? 
ATOM   2680 C CE1   . PHE A 1 353 ? 18.635  13.765  -13.603 1.000 23.069  0 352  PHE A CE1   1 ? 
ATOM   2681 C CE2   . PHE A 1 353 ? 17.554  15.888  -13.470 1.000 23.437  0 352  PHE A CE2   1 ? 
ATOM   2682 C CZ    . PHE A 1 353 ? 18.166  14.812  -12.858 1.000 24.723  0 352  PHE A CZ    1 ? 
ATOM   2683 N N     . LEU A 1 354 ? 18.748  15.019  -20.226 1.000 18.384  0 353  LEU A N     1 ? 
ATOM   2684 C CA    . LEU A 1 354 ? 18.667  14.626  -21.639 1.000 18.399  0 353  LEU A CA    1 ? 
ATOM   2685 C C     . LEU A 1 354 ? 19.875  13.765  -22.039 1.000 19.936  0 353  LEU A C     1 ? 
ATOM   2686 O O     . LEU A 1 354 ? 19.765  12.796  -22.818 1.000 19.928  0 353  LEU A O     1 ? 
ATOM   2687 C CB    . LEU A 1 354 ? 18.510  15.848  -22.546 1.000 19.865  0 353  LEU A CB    1 ? 
ATOM   2688 C CG    . LEU A 1 354 ? 18.429  15.592  -24.048 1.000 19.765  0 353  LEU A CG    1 ? 
ATOM   2689 C CD1   . LEU A 1 354 ? 17.331  14.647  -24.491 1.000 20.618  0 353  LEU A CD1   1 ? 
ATOM   2690 C CD2   . LEU A 1 354 ? 18.273  16.912  -24.781 1.000 22.984  0 353  LEU A CD2   1 ? 
ATOM   2691 N N     . ALA A 1 355 ? 21.065  14.168  -21.579 1.000 21.390  0 354  ALA A N     1 ? 
ATOM   2692 C CA    . ALA A 1 355 ? 22.270  13.426  -21.873 1.000 23.610  0 354  ALA A CA    1 ? 
ATOM   2693 C C     . ALA A 1 355 ? 22.148  12.021  -21.292 1.000 22.857  0 354  ALA A C     1 ? 
ATOM   2694 O O     . ALA A 1 355 ? 22.530  11.063  -21.954 1.000 19.636  0 354  ALA A O     1 ? 
ATOM   2695 C CB    . ALA A 1 355 ? 23.506  14.139  -21.348 1.000 24.979  0 354  ALA A CB    1 ? 
ATOM   2696 N N     . GLN A 1 356 ? 21.616  11.893  -20.066 1.000 21.897  0 355  GLN A N     1 ? 
ATOM   2697 C CA    . GLN A 1 356 ? 21.420  10.571  -19.496 1.000 22.245  0 355  GLN A CA    1 ? 
ATOM   2698 C C     . GLN A 1 356 ? 20.487  9.719   -20.373 1.000 23.257  0 355  GLN A C     1 ? 
ATOM   2699 O O     . GLN A 1 356 ? 20.770  8.555   -20.623 1.000 21.853  0 355  GLN A O     1 ? 
ATOM   2700 C CB    . GLN A 1 356 ? 20.907  10.672  -18.066 1.000 23.035  0 355  GLN A CB    1 ? 
ATOM   2701 C CG    . GLN A 1 356 ? 20.618  9.327   -17.414 1.000 22.544  0 355  GLN A CG    1 ? 
ATOM   2702 C CD    . GLN A 1 356 ? 20.019  9.485   -16.038 1.000 26.315  0 355  GLN A CD    1 ? 
ATOM   2703 O OE1   . GLN A 1 356 ? 20.039  10.577  -15.468 1.000 28.113  0 355  GLN A OE1   1 ? 
ATOM   2704 N NE2   . GLN A 1 356 ? 19.478  8.401   -15.496 1.000 27.125  0 355  GLN A NE2   1 ? 
ATOM   2705 N N     . TRP A 1 357 ? 19.371  10.316  -20.818 1.000 22.497  0 356  TRP A N     1 ? 
ATOM   2706 C CA    . TRP A 1 357 ? 18.418  9.681   -21.713 1.000 20.411  0 356  TRP A CA    1 ? 
ATOM   2707 C C     . TRP A 1 357 ? 19.094  9.227   -23.007 1.000 21.547  0 356  TRP A C     1 ? 
ATOM   2708 O O     . TRP A 1 357 ? 18.868  8.113   -23.486 1.000 20.110  0 356  TRP A O     1 ? 
ATOM   2709 C CB    . TRP A 1 357 ? 17.270  10.652  -21.995 1.000 19.043  0 356  TRP A CB    1 ? 
ATOM   2710 C CG    . TRP A 1 357 ? 16.131  10.032  -22.763 1.000 19.730  0 356  TRP A CG    1 ? 
ATOM   2711 C CD1   . TRP A 1 357 ? 15.036  9.425   -22.229 1.000 20.240  0 356  TRP A CD1   1 ? 
ATOM   2712 C CD2   . TRP A 1 357 ? 16.015  9.910   -24.189 1.000 19.189  0 356  TRP A CD2   1 ? 
ATOM   2713 N NE1   . TRP A 1 357 ? 14.199  9.002   -23.220 1.000 20.251  0 356  TRP A NE1   1 ? 
ATOM   2714 C CE2   . TRP A 1 357 ? 14.767  9.278   -24.434 1.000 19.323  0 356  TRP A CE2   1 ? 
ATOM   2715 C CE3   . TRP A 1 357 ? 16.810  10.286  -25.271 1.000 21.453  0 356  TRP A CE3   1 ? 
ATOM   2716 C CZ2   . TRP A 1 357 ? 14.329  8.986   -25.720 1.000 20.476  0 356  TRP A CZ2   1 ? 
ATOM   2717 C CZ3   . TRP A 1 357 ? 16.393  9.990   -26.551 1.000 19.224  0 356  TRP A CZ3   1 ? 
ATOM   2718 C CH2   . TRP A 1 357 ? 15.143  9.368   -26.764 1.000 22.188  0 356  TRP A CH2   1 ? 
ATOM   2719 N N     . LYS A 1 358 ? 19.914  10.094  -23.603 1.000 21.450  0 357  LYS A N     1 ? 
ATOM   2720 C CA    . LYS A 1 358 ? 20.547  9.733   -24.862 1.000 23.200  0 357  LYS A CA    1 ? 
ATOM   2721 C C     . LYS A 1 358 ? 21.543  8.603   -24.634 1.000 24.055  0 357  LYS A C     1 ? 
ATOM   2722 O O     . LYS A 1 358 ? 21.732  7.800   -25.528 1.000 24.417  0 357  LYS A O     1 ? 
ATOM   2723 C CB    . LYS A 1 358 ? 21.268  10.922  -25.486 1.000 26.964  0 357  LYS A CB    1 ? 
ATOM   2724 C CG    . LYS A 1 358 ? 20.365  12.013  -26.004 1.000 29.363  0 357  LYS A CG    1 ? 
ATOM   2725 C CD    . LYS A 1 358 ? 20.373  12.162  -27.516 1.000 38.840  0 357  LYS A CD    1 ? 
ATOM   2726 C CE    . LYS A 1 358 ? 19.403  13.193  -28.015 1.000 41.204  0 357  LYS A CE    1 ? 
ATOM   2727 N NZ    . LYS A 1 358 ? 19.903  14.546  -27.800 1.000 41.530  0 357  LYS A NZ    1 ? 
ATOM   2728 N N     . GLN A 1 359 ? 22.113  8.522   -23.436 1.000 21.408  0 358  GLN A N     1 ? 
ATOM   2729 C CA    . GLN A 1 359 ? 23.107  7.509   -23.096 1.000 28.152  0 358  GLN A CA    1 ? 
ATOM   2730 C C     . GLN A 1 359 ? 22.476  6.131   -22.872 1.000 25.504  0 358  GLN A C     1 ? 
ATOM   2731 O O     . GLN A 1 359 ? 22.952  5.147   -23.417 1.000 24.657  0 358  GLN A O     1 ? 
ATOM   2732 C CB    . GLN A 1 359 ? 23.833  7.871   -21.799 1.000 34.001  0 358  GLN A CB    1 ? 
ATOM   2733 C CG    . GLN A 1 359 ? 24.946  6.912   -21.396 1.000 40.069  0 358  GLN A CG    1 ? 
ATOM   2734 C CD    . GLN A 1 359 ? 26.178  7.123   -22.251 1.000 53.073  0 358  GLN A CD    1 ? 
ATOM   2735 O OE1   . GLN A 1 359 ? 26.635  8.260   -22.441 1.000 59.868  0 358  GLN A OE1   1 ? 
ATOM   2736 N NE2   . GLN A 1 359 ? 26.698  6.043   -22.815 1.000 56.041  0 358  GLN A NE2   1 ? 
ATOM   2737 N N     . ASN A 1 360 ? 21.432  6.018   -22.041 1.000 22.080  0 359  ASN A N     1 ? 
ATOM   2738 C CA    . ASN A 1 360 ? 20.869  4.703   -21.800 1.000 24.340  0 359  ASN A CA    1 ? 
ATOM   2739 C C     . ASN A 1 360 ? 19.364  4.739   -21.547 1.000 22.678  0 359  ASN A C     1 ? 
ATOM   2740 O O     . ASN A 1 360 ? 18.837  3.797   -20.985 1.000 22.861  0 359  ASN A O     1 ? 
ATOM   2741 C CB    . ASN A 1 360 ? 21.568  3.969   -20.672 1.000 29.312  0 359  ASN A CB    1 ? 
ATOM   2742 C CG    . ASN A 1 360 ? 21.390  4.685   -19.364 1.000 34.135  0 359  ASN A CG    1 ? 
ATOM   2743 O OD1   . ASN A 1 360 ? 20.720  5.722   -19.293 1.000 29.963  0 359  ASN A OD1   1 ? 
ATOM   2744 N ND2   . ASN A 1 360 ? 21.979  4.140   -18.311 1.000 42.362  0 359  ASN A ND2   1 ? 
ATOM   2745 N N     . ARG A 1 361 ? 18.675  5.801   -21.979 1.000 22.575  0 360  ARG A N     1 ? 
ATOM   2746 C CA    . ARG A 1 361 ? 17.213  5.837   -21.962 1.000 21.089  0 360  ARG A CA    1 ? 
ATOM   2747 C C     . ARG A 1 361 ? 16.681  5.634   -20.543 1.000 22.449  0 360  ARG A C     1 ? 
ATOM   2748 O O     . ARG A 1 361 ? 15.667  4.936   -20.361 1.000 24.132  0 360  ARG A O     1 ? 
ATOM   2749 C CB    . ARG A 1 361 ? 16.602  4.790   -22.897 1.000 20.700  0 360  ARG A CB    1 ? 
ATOM   2750 C CG    . ARG A 1 361 ? 16.890  4.929   -24.385 1.000 20.103  0 360  ARG A CG    1 ? 
ATOM   2751 C CD    . ARG A 1 361 ? 16.498  6.252   -24.986 1.000 22.946  0 360  ARG A CD    1 ? 
ATOM   2752 N NE    . ARG A 1 361 ? 16.538  6.236   -26.460 1.000 26.642  0 360  ARG A NE    1 ? 
ATOM   2753 C CZ    . ARG A 1 361 ? 17.581  6.646   -27.183 1.000 38.183  0 360  ARG A CZ    1 ? 
ATOM   2754 N NH1   . ARG A 1 361 ? 18.722  7.018   -26.606 1.000 36.613  0 360  ARG A NH1   1 ? 
ATOM   2755 N NH2   . ARG A 1 361 ? 17.505  6.662   -28.505 1.000 39.810  0 360  ARG A NH2   1 ? 
ATOM   2756 N N     . THR A 1 362 ? 17.340  6.262   -19.548 1.000 20.382  0 361  THR A N     1 ? 
ATOM   2757 C CA    . THR A 1 362 ? 16.841  6.264   -18.181 1.000 21.675  0 361  THR A CA    1 ? 
ATOM   2758 C C     . THR A 1 362 ? 16.704  7.691   -17.649 1.000 19.811  0 361  THR A C     1 ? 
ATOM   2759 O O     . THR A 1 362 ? 17.106  8.667   -18.274 1.000 19.922  0 361  THR A O     1 ? 
ATOM   2760 C CB    . THR A 1 362 ? 17.721  5.434   -17.246 1.000 26.645  0 361  THR A CB    1 ? 
ATOM   2761 O OG1   . THR A 1 362 ? 18.954  6.140   -17.082 1.000 26.391  0 361  THR A OG1   1 ? 
ATOM   2762 C CG2   . THR A 1 362 ? 17.944  4.028   -17.782 1.000 30.039  0 361  THR A CG2   1 ? 
ATOM   2763 N N     . GLY A 1 363 ? 16.084  7.757   -16.477 1.000 19.088  0 362  GLY A N     1 ? 
ATOM   2764 C CA    . GLY A 1 363 ? 16.033  8.952   -15.669 1.000 19.844  0 362  GLY A CA    1 ? 
ATOM   2765 C C     . GLY A 1 363 ? 14.766  9.756   -15.924 1.000 18.756  0 362  GLY A C     1 ? 
ATOM   2766 O O     . GLY A 1 363 ? 13.860  9.300   -16.640 1.000 17.939  0 362  GLY A O     1 ? 
ATOM   2767 N N     . PRO A 1 364 ? 14.680  10.977  -15.343 1.000 20.646  0 363  PRO A N     1 ? 
ATOM   2768 C CA    . PRO A 1 364 ? 13.454  11.785  -15.402 1.000 20.079  0 363  PRO A CA    1 ? 
ATOM   2769 C C     . PRO A 1 364 ? 12.876  12.031  -16.811 1.000 19.192  0 363  PRO A C     1 ? 
ATOM   2770 O O     . PRO A 1 364 ? 11.650  12.212  -16.979 1.000 18.987  0 363  PRO A O     1 ? 
ATOM   2771 C CB    . PRO A 1 364 ? 13.907  13.091  -14.738 1.000 21.757  0 363  PRO A CB    1 ? 
ATOM   2772 C CG    . PRO A 1 364 ? 15.048  12.683  -13.794 1.000 22.925  0 363  PRO A CG    1 ? 
ATOM   2773 C CD    . PRO A 1 364 ? 15.776  11.621  -14.585 1.000 22.641  0 363  PRO A CD    1 ? 
ATOM   2774 N N     . MET A 1 365 ? 13.728  11.964  -17.831 1.000 17.493  0 364  MET A N     1 ? 
ATOM   2775 C CA    . MET A 1 365 ? 13.274  12.246  -19.191 1.000 19.285  0 364  MET A CA    1 ? 
ATOM   2776 C C     . MET A 1 365 ? 12.339  11.167  -19.736 1.000 20.104  0 364  MET A C     1 ? 
ATOM   2777 O O     . MET A 1 365 ? 11.747  11.354  -20.809 1.000 18.705  0 364  MET A O     1 ? 
ATOM   2778 C CB    . MET A 1 365 ? 14.439  12.421  -20.167 1.000 20.548  0 364  MET A CB    1 ? 
ATOM   2779 C CG    . MET A 1 365 ? 15.146  13.768  -19.972 1.000 23.295  0 364  MET A CG    1 ? 
ATOM   2780 S SD    . MET A 1 365 ? 14.121  15.181  -20.462 1.000 25.605  0 364  MET A SD    1 ? 
ATOM   2781 C CE    . MET A 1 365 ? 14.627  16.565  -19.435 1.000 22.532  0 364  MET A CE    1 ? 
ATOM   2782 N N     . VAL A 1 366 ? 12.203  10.042  -19.028 1.000 18.535  0 365  VAL A N     1 ? 
ATOM   2783 C CA    . VAL A 1 366 ? 11.298  8.995   -19.490 1.000 17.506  0 365  VAL A CA    1 ? 
ATOM   2784 C C     . VAL A 1 366 ? 9.881   9.213   -18.947 1.000 17.388  0 365  VAL A C     1 ? 
ATOM   2785 O O     . VAL A 1 366 ? 8.971   8.487   -19.323 1.000 17.439  0 365  VAL A O     1 ? 
ATOM   2786 C CB    . VAL A 1 366 ? 11.768  7.550   -19.252 1.000 17.781  0 365  VAL A CB    1 ? 
ATOM   2787 C CG1   . VAL A 1 366 ? 13.192  7.331   -19.789 1.000 18.965  0 365  VAL A CG1   1 ? 
ATOM   2788 C CG2   . VAL A 1 366 ? 11.612  7.142   -17.790 1.000 17.485  0 365  VAL A CG2   1 ? 
ATOM   2789 N N     . ALA A 1 367 ? 9.686   10.160  -18.035 1.000 16.917  0 366  ALA A N     1 ? 
ATOM   2790 C CA    . ALA A 1 367 ? 8.375   10.409  -17.471 1.000 17.702  0 366  ALA A CA    1 ? 
ATOM   2791 C C     . ALA A 1 367 ? 7.500   11.306  -18.333 1.000 19.309  0 366  ALA A C     1 ? 
ATOM   2792 O O     . ALA A 1 367 ? 7.961   12.298  -18.893 1.000 20.644  0 366  ALA A O     1 ? 
ATOM   2793 C CB    . ALA A 1 367 ? 8.513   10.982  -16.083 1.000 18.009  0 366  ALA A CB    1 ? 
ATOM   2794 N N     . SER A 1 368 ? 6.194   10.983  -18.338 1.000 17.338  0 367  SER A N     1 ? 
ATOM   2795 C CA    . SER A 1 368 ? 5.170   11.868  -18.847 1.000 19.310  0 367  SER A CA    1 ? 
ATOM   2796 C C     . SER A 1 368 ? 4.906   12.982  -17.842 1.000 18.922  0 367  SER A C     1 ? 
ATOM   2797 O O     . SER A 1 368 ? 5.346   12.898  -16.684 1.000 21.259  0 367  SER A O     1 ? 
ATOM   2798 C CB    . SER A 1 368 ? 3.891   11.098  -19.146 1.000 17.591  0 367  SER A CB    1 ? 
ATOM   2799 O OG    . SER A 1 368 ? 3.130   10.861  -17.980 1.000 18.773  0 367  SER A OG    1 ? 
ATOM   2800 N N     . PRO A 1 369 ? 4.063   13.970  -18.227 1.000 19.636  0 368  PRO A N     1 ? 
ATOM   2801 C CA    . PRO A 1 369 ? 3.702   15.098  -17.361 1.000 20.104  0 368  PRO A CA    1 ? 
ATOM   2802 C C     . PRO A 1 369 ? 2.694   14.814  -16.245 1.000 19.719  0 368  PRO A C     1 ? 
ATOM   2803 O O     . PRO A 1 369 ? 2.288   15.727  -15.548 1.000 20.040  0 368  PRO A O     1 ? 
ATOM   2804 C CB    . PRO A 1 369 ? 3.123   16.150  -18.301 1.000 23.097  0 368  PRO A CB    1 ? 
ATOM   2805 C CG    . PRO A 1 369 ? 3.374   15.652  -19.678 1.000 22.614  0 368  PRO A CG    1 ? 
ATOM   2806 C CD    . PRO A 1 369 ? 3.567   14.159  -19.600 1.000 21.295  0 368  PRO A CD    1 ? 
ATOM   2807 N N     . SER A 1 370 ? 2.294   13.560  -16.040 1.000 19.498  0 369  SER A N     1 ? 
ATOM   2808 C CA    . SER A 1 370 ? 1.401   13.285  -14.940 1.000 19.898  0 369  SER A CA    1 ? 
ATOM   2809 C C     . SER A 1 370 ? 1.800   11.945  -14.364 1.000 18.624  0 369  SER A C     1 ? 
ATOM   2810 O O     . SER A 1 370 ? 2.459   11.176  -15.055 1.000 18.424  0 369  SER A O     1 ? 
ATOM   2811 C CB    . SER A 1 370 ? -0.064  13.315  -15.343 1.000 23.305  0 369  SER A CB    1 ? 
ATOM   2812 O OG    . SER A 1 370 ? -0.417  12.168  -16.102 1.000 23.730  0 369  SER A OG    1 ? 
ATOM   2813 N N     . THR A 1 371 ? 1.414   11.706  -13.104 1.000 17.051  0 370  THR A N     1 ? 
ATOM   2814 C CA    . THR A 1 371 ? 1.764   10.473  -12.414 1.000 17.099  0 370  THR A CA    1 ? 
ATOM   2815 C C     . THR A 1 371 ? 0.552   9.564   -12.235 1.000 18.781  0 370  THR A C     1 ? 
ATOM   2816 O O     . THR A 1 371 ? 0.673   8.317   -12.147 1.000 22.040  0 370  THR A O     1 ? 
ATOM   2817 C CB    . THR A 1 371 ? 2.368   10.791  -11.042 1.000 18.156  0 370  THR A CB    1 ? 
ATOM   2818 O OG1   . THR A 1 371 ? 1.396   11.453  -10.254 1.000 20.761  0 370  THR A OG1   1 ? 
ATOM   2819 C CG2   . THR A 1 371 ? 3.612   11.665  -11.091 1.000 18.828  0 370  THR A CG2   1 ? 
ATOM   2820 N N     . GLY A 1 372 ? -0.602  10.199  -12.059 1.000 18.528  0 371  GLY A N     1 ? 
ATOM   2821 C CA    . GLY A 1 372 ? -1.817  9.490   -11.719 1.000 18.787  0 371  GLY A CA    1 ? 
ATOM   2822 C C     . GLY A 1 372 ? -3.039  10.299  -12.140 1.000 17.921  0 371  GLY A C     1 ? 
ATOM   2823 O O     . GLY A 1 372 ? -2.994  11.517  -12.263 1.000 19.470  0 371  GLY A O     1 ? 
ATOM   2824 N N     . LEU A 1 373 ? -4.127  9.600   -12.418 1.000 17.737  0 372  LEU A N     1 ? 
ATOM   2825 C CA    . LEU A 1 373 ? -5.357  10.194  -12.915 1.000 17.204  0 372  LEU A CA    1 ? 
ATOM   2826 C C     . LEU A 1 373 ? -6.494  9.684   -12.050 1.000 18.037  0 372  LEU A C     1 ? 
ATOM   2827 O O     . LEU A 1 373 ? -6.599  8.486   -11.838 1.000 19.725  0 372  LEU A O     1 ? 
ATOM   2828 C CB    . LEU A 1 373 ? -5.629  9.762   -14.358 1.000 18.757  0 372  LEU A CB    1 ? 
ATOM   2829 C CG    . LEU A 1 373 ? -4.508  9.924   -15.384 1.000 20.950  0 372  LEU A CG    1 ? 
ATOM   2830 C CD1   . LEU A 1 373 ? -4.976  9.424   -16.718 1.000 21.536  0 372  LEU A CD1   1 ? 
ATOM   2831 C CD2   . LEU A 1 373 ? -4.029  11.366  -15.547 1.000 21.706  0 372  LEU A CD2   1 ? 
ATOM   2832 N N     . GLY A 1 374 ? -7.365  10.587  -11.605 1.000 18.207  0 373  GLY A N     1 ? 
ATOM   2833 C CA    . GLY A 1 374 ? -8.528  10.175  -10.848 1.000 18.691  0 373  GLY A CA    1 ? 
ATOM   2834 C C     . GLY A 1 374 ? -9.814  10.643  -11.493 1.000 17.515  0 373  GLY A C     1 ? 
ATOM   2835 O O     . GLY A 1 374 ? -9.924  11.799  -11.890 1.000 19.604  0 373  GLY A O     1 ? 
ATOM   2836 N N     . PHE A 1 375 ? -10.777 9.728   -11.625 1.000 17.473  0 374  PHE A N     1 ? 
ATOM   2837 C CA    . PHE A 1 375 ? -12.038 10.010  -12.280 1.000 18.344  0 374  PHE A CA    1 ? 
ATOM   2838 C C     . PHE A 1 375 ? -13.167 9.852   -11.260 1.000 18.615  0 374  PHE A C     1 ? 
ATOM   2839 O O     . PHE A 1 375 ? -13.246 8.796   -10.621 1.000 20.312  0 374  PHE A O     1 ? 
ATOM   2840 C CB    . PHE A 1 375 ? -12.271 9.060   -13.458 1.000 19.634  0 374  PHE A CB    1 ? 
ATOM   2841 C CG    . PHE A 1 375 ? -11.229 9.245   -14.550 1.000 18.546  0 374  PHE A CG    1 ? 
ATOM   2842 C CD1   . PHE A 1 375 ? -9.997  8.606   -14.470 1.000 19.633  0 374  PHE A CD1   1 ? 
ATOM   2843 C CD2   . PHE A 1 375 ? -11.421 10.189  -15.542 1.000 17.562  0 374  PHE A CD2   1 ? 
ATOM   2844 C CE1   . PHE A 1 375 ? -9.025  8.822   -15.430 1.000 18.707  0 374  PHE A CE1   1 ? 
ATOM   2845 C CE2   . PHE A 1 375 ? -10.432 10.441  -16.484 1.000 18.893  0 374  PHE A CE2   1 ? 
ATOM   2846 C CZ    . PHE A 1 375 ? -9.229  9.766   -16.420 1.000 17.947  0 374  PHE A CZ    1 ? 
ATOM   2847 N N     . PHE A 1 376 ? -14.037 10.872  -11.162 1.000 18.131  0 375  PHE A N     1 ? 
ATOM   2848 C CA    . PHE A 1 376 ? -15.111 10.912  -10.176 1.000 19.237  0 375  PHE A CA    1 ? 
ATOM   2849 C C     . PHE A 1 376 ? -16.395 11.454  -10.772 1.000 18.725  0 375  PHE A C     1 ? 
ATOM   2850 O O     . PHE A 1 376 ? -16.416 12.296  -11.679 1.000 18.659  0 375  PHE A O     1 ? 
ATOM   2851 C CB    . PHE A 1 376 ? -14.725 11.710  -8.920  1.000 19.848  0 375  PHE A CB    1 ? 
ATOM   2852 C CG    . PHE A 1 376 ? -13.403 11.186  -8.395  1.000 21.672  0 375  PHE A CG    1 ? 
ATOM   2853 C CD1   . PHE A 1 376 ? -13.352 9.999   -7.675  1.000 21.591  0 375  PHE A CD1   1 ? 
ATOM   2854 C CD2   . PHE A 1 376 ? -12.214 11.848  -8.690  1.000 22.241  0 375  PHE A CD2   1 ? 
ATOM   2855 C CE1   . PHE A 1 376 ? -12.126 9.460   -7.320  1.000 23.363  0 375  PHE A CE1   1 ? 
ATOM   2856 C CE2   . PHE A 1 376 ? -10.997 11.341  -8.264  1.000 22.237  0 375  PHE A CE2   1 ? 
ATOM   2857 C CZ    . PHE A 1 376 ? -10.955 10.152  -7.588  1.000 23.154  0 375  PHE A CZ    1 ? 
ATOM   2858 N N     . ARG A 1 377 ? -17.499 10.931  -10.237 1.000 20.348  0 376  ARG A N     1 ? 
ATOM   2859 C CA    . ARG A 1 377 ? -18.826 11.394  -10.591 1.000 20.957  0 376  ARG A CA    1 ? 
ATOM   2860 C C     . ARG A 1 377 ? -19.369 12.333  -9.524  1.000 23.452  0 376  ARG A C     1 ? 
ATOM   2861 O O     . ARG A 1 377 ? -19.132 12.166  -8.334  1.000 24.285  0 376  ARG A O     1 ? 
ATOM   2862 C CB    . ARG A 1 377 ? -19.770 10.193  -10.745 1.000 20.555  0 376  ARG A CB    1 ? 
ATOM   2863 C CG    . ARG A 1 377 ? -19.372 9.328   -11.926 1.000 20.802  0 376  ARG A CG    1 ? 
ATOM   2864 C CD    . ARG A 1 377 ? -20.320 8.163   -12.101 1.000 21.287  0 376  ARG A CD    1 ? 
ATOM   2865 N NE    . ARG A 1 377 ? -21.649 8.653   -12.490 1.000 21.069  0 376  ARG A NE    1 ? 
ATOM   2866 C CZ    . ARG A 1 377 ? -21.975 9.124   -13.694 1.000 22.922  0 376  ARG A CZ    1 ? 
ATOM   2867 N NH1   . ARG A 1 377 ? -21.107 9.068   -14.688 1.000 24.135  0 376  ARG A NH1   1 ? 
ATOM   2868 N NH2   . ARG A 1 377 ? -23.184 9.608   -13.917 1.000 23.358  0 376  ARG A NH2   1 ? 
ATOM   2869 N N     . LEU A 1 378 ? -20.146 13.320  -9.944  1.000 24.664  0 377  LEU A N     1 ? 
ATOM   2870 C CA    . LEU A 1 378 ? -21.043 13.976  -9.004  1.000 27.611  0 377  LEU A CA    1 ? 
ATOM   2871 C C     . LEU A 1 378 ? -22.025 12.940  -8.437  1.000 28.085  0 377  LEU A C     1 ? 
ATOM   2872 O O     . LEU A 1 378 ? -22.497 12.045  -9.126  1.000 31.061  0 377  LEU A O     1 ? 
ATOM   2873 C CB    . LEU A 1 378 ? -21.781 15.102  -9.720  1.000 27.407  0 377  LEU A CB    1 ? 
ATOM   2874 C CG    . LEU A 1 378 ? -20.937 16.180  -10.408 1.000 33.240  0 377  LEU A CG    1 ? 
ATOM   2875 C CD1   . LEU A 1 378 ? -21.820 17.111  -11.202 1.000 35.587  0 377  LEU A CD1   1 ? 
ATOM   2876 C CD2   . LEU A 1 378 ? -20.134 16.972  -9.383  1.000 34.340  0 377  LEU A CD2   1 ? 
ATOM   2877 N N     . PRO A 1 379 ? -22.468 13.079  -7.178  1.000 37.460  0 378  PRO A N     1 ? 
ATOM   2878 C CA    . PRO A 1 379 ? -23.473 12.155  -6.630  1.000 42.426  0 378  PRO A CA    1 ? 
ATOM   2879 C C     . PRO A 1 379 ? -24.722 12.018  -7.512  1.000 39.798  0 378  PRO A C     1 ? 
ATOM   2880 O O     . PRO A 1 379 ? -25.184 13.001  -8.075  1.000 41.888  0 378  PRO A O     1 ? 
ATOM   2881 C CB    . PRO A 1 379 ? -23.811 12.757  -5.261  1.000 47.272  0 378  PRO A CB    1 ? 
ATOM   2882 C CG    . PRO A 1 379 ? -22.736 13.808  -4.971  1.000 46.075  0 378  PRO A CG    1 ? 
ATOM   2883 C CD    . PRO A 1 379 ? -22.078 14.175  -6.287  1.000 40.163  0 378  PRO A CD    1 ? 
ATOM   2884 N N     . ASP A 1 380 ? -25.239 10.795  -7.683  1.000 42.046  0 379  ASP A N     1 ? 
ATOM   2885 C CA    . ASP A 1 380 ? -26.496 10.591  -8.396  1.000 47.698  0 379  ASP A CA    1 ? 
ATOM   2886 C C     . ASP A 1 380 ? -27.568 11.528  -7.845  1.000 45.909  0 379  ASP A C     1 ? 
ATOM   2887 O O     . ASP A 1 380 ? -28.193 12.269  -8.589  1.000 42.714  0 379  ASP A O     1 ? 
ATOM   2888 C CB    . ASP A 1 380 ? -26.981 9.149   -8.346  1.000 50.536  0 379  ASP A CB    1 ? 
ATOM   2889 C CG    . ASP A 1 380 ? -26.621 8.277   -9.541  1.000 54.986  0 379  ASP A CG    1 ? 
ATOM   2890 O OD1   . ASP A 1 380 ? -25.892 8.755   -10.437 1.000 52.391  0 379  ASP A OD1   1 ? 
ATOM   2891 O OD2   . ASP A 1 380 ? -27.113 7.132   -9.591  1.000 57.728  0 379  ASP A OD2   1 ? 
ATOM   2892 N N     . ASN A 1 381 ? -27.734 11.538  -6.524  1.000 42.802  0 380  ASN A N     1 ? 
ATOM   2893 C CA    . ASN A 1 381 ? -28.756 12.363  -5.893  1.000 47.738  0 380  ASN A CA    1 ? 
ATOM   2894 C C     . ASN A 1 381 ? -28.335 13.832  -5.832  1.000 43.494  0 380  ASN A C     1 ? 
ATOM   2895 O O     . ASN A 1 381 ? -28.862 14.558  -5.005  1.000 39.847  0 380  ASN A O     1 ? 
ATOM   2896 C CB    . ASN A 1 381 ? -29.106 11.854  -4.495  1.000 45.340  0 380  ASN A CB    1 ? 
ATOM   2897 C CG    . ASN A 1 381 ? -27.888 11.627  -3.610  1.000 54.300  0 380  ASN A CG    1 ? 
ATOM   2898 O OD1   . ASN A 1 381 ? -26.729 11.868  -3.998  1.000 44.770  0 380  ASN A OD1   1 ? 
ATOM   2899 N ND2   . ASN A 1 381 ? -28.130 11.156  -2.393  1.000 55.296  0 380  ASN A ND2   1 ? 
ATOM   2900 N N     . ASP A 1 382 ? -27.403 14.282  -6.685  1.000 43.227  0 381  ASP A N     1 ? 
ATOM   2901 C CA    . ASP A 1 382 ? -26.926 15.663  -6.644  1.000 41.428  0 381  ASP A CA    1 ? 
ATOM   2902 C C     . ASP A 1 382 ? -27.929 16.585  -7.323  1.000 40.947  0 381  ASP A C     1 ? 
ATOM   2903 O O     . ASP A 1 382 ? -28.443 16.239  -8.375  1.000 39.597  0 381  ASP A O     1 ? 
ATOM   2904 C CB    . ASP A 1 382 ? -25.588 15.830  -7.362  1.000 45.828  0 381  ASP A CB    1 ? 
ATOM   2905 C CG    . ASP A 1 382 ? -24.837 17.147  -7.190  1.000 48.244  0 381  ASP A CG    1 ? 
ATOM   2906 O OD1   . ASP A 1 382 ? -25.354 18.216  -7.589  1.000 45.459  0 381  ASP A OD1   1 ? 
ATOM   2907 O OD2   . ASP A 1 382 ? -23.690 17.090  -6.692  1.000 58.324  0 381  ASP A OD2   1 ? 
ATOM   2908 N N     . THR A 1 383 ? -28.046 17.817  -6.804  1.000 43.901  0 382  THR A N     1 ? 
ATOM   2909 C CA    . THR A 1 383 ? -29.067 18.793  -7.177  1.000 42.495  0 382  THR A CA    1 ? 
ATOM   2910 C C     . THR A 1 383 ? -29.014 19.202  -8.648  1.000 37.779  0 382  THR A C     1 ? 
ATOM   2911 O O     . THR A 1 383 ? -30.044 19.507  -9.220  1.000 35.221  0 382  THR A O     1 ? 
ATOM   2912 C CB    . THR A 1 383 ? -28.894 20.047  -6.318  1.000 48.439  0 382  THR A CB    1 ? 
ATOM   2913 O OG1   . THR A 1 383 ? -29.202 19.598  -5.003  1.000 54.622  0 382  THR A OG1   1 ? 
ATOM   2914 C CG2   . THR A 1 383 ? -29.813 21.177  -6.755  1.000 44.421  0 382  THR A CG2   1 ? 
ATOM   2915 N N     . ILE A 1 384 ? -27.814 19.349  -9.219  1.000 32.326  0 383  ILE A N     1 ? 
ATOM   2916 C CA    . ILE A 1 384 ? -27.634 19.863  -10.570 1.000 29.317  0 383  ILE A CA    1 ? 
ATOM   2917 C C     . ILE A 1 384 ? -28.347 18.988  -11.614 1.000 24.546  0 383  ILE A C     1 ? 
ATOM   2918 O O     . ILE A 1 384 ? -28.666 19.458  -12.713 1.000 27.673  0 383  ILE A O     1 ? 
ATOM   2919 C CB    . ILE A 1 384 ? -26.120 19.943  -10.869 1.000 36.225  0 383  ILE A CB    1 ? 
ATOM   2920 C CG1   . ILE A 1 384 ? -25.792 20.750  -12.101 1.000 38.535  0 383  ILE A CG1   1 ? 
ATOM   2921 C CG2   . ILE A 1 384 ? -25.508 18.547  -10.925 1.000 35.776  0 383  ILE A CG2   1 ? 
ATOM   2922 C CD1   . ILE A 1 384 ? -25.759 22.243  -11.860 1.000 43.850  0 383  ILE A CD1   1 ? 
ATOM   2923 N N     . PHE A 1 385 ? -28.567 17.707  -11.305 1.000 25.268  0 384  PHE A N     1 ? 
ATOM   2924 C CA    . PHE A 1 385 ? -29.220 16.804  -12.251 1.000 27.812  0 384  PHE A CA    1 ? 
ATOM   2925 C C     . PHE A 1 385 ? -30.750 16.958  -12.271 1.000 31.694  0 384  PHE A C     1 ? 
ATOM   2926 O O     . PHE A 1 385 ? -31.415 16.216  -12.996 1.000 27.995  0 384  PHE A O     1 ? 
ATOM   2927 C CB    . PHE A 1 385 ? -28.862 15.361  -11.919 1.000 26.866  0 384  PHE A CB    1 ? 
ATOM   2928 C CG    . PHE A 1 385 ? -27.376 15.082  -12.099 1.000 26.010  0 384  PHE A CG    1 ? 
ATOM   2929 C CD1   . PHE A 1 385 ? -26.773 15.219  -13.343 1.000 23.404  0 384  PHE A CD1   1 ? 
ATOM   2930 C CD2   . PHE A 1 385 ? -26.615 14.618  -11.032 1.000 25.709  0 384  PHE A CD2   1 ? 
ATOM   2931 C CE1   . PHE A 1 385 ? -25.412 14.948  -13.484 1.000 22.787  0 384  PHE A CE1   1 ? 
ATOM   2932 C CE2   . PHE A 1 385 ? -25.259 14.324  -11.192 1.000 26.305  0 384  PHE A CE2   1 ? 
ATOM   2933 C CZ    . PHE A 1 385 ? -24.674 14.493  -12.416 1.000 22.280  0 384  PHE A CZ    1 ? 
ATOM   2934 N N     . GLU A 1 386 ? -31.300 17.898  -11.483 1.000 35.620  0 385  GLU A N     1 ? 
ATOM   2935 C CA    . GLU A 1 386 ? -32.664 18.380  -11.693 1.000 35.758  0 385  GLU A CA    1 ? 
ATOM   2936 C C     . GLU A 1 386 ? -32.786 19.152  -13.004 1.000 33.446  0 385  GLU A C     1 ? 
ATOM   2937 O O     . GLU A 1 386 ? -33.807 19.058  -13.694 1.000 31.180  0 385  GLU A O     1 ? 
ATOM   2938 C CB    . GLU A 1 386 ? -33.061 19.321  -10.561 1.000 36.328  0 385  GLU A CB    1 ? 
ATOM   2939 C CG    . GLU A 1 386 ? -33.274 18.554  -9.268  1.000 43.638  0 385  GLU A CG    1 ? 
ATOM   2940 C CD    . GLU A 1 386 ? -33.561 19.412  -8.055  1.000 49.176  0 385  GLU A CD    1 ? 
ATOM   2941 O OE1   . GLU A 1 386 ? -33.729 20.645  -8.173  1.000 57.712  0 385  GLU A OE1   1 ? 
ATOM   2942 O OE2   . GLU A 1 386 ? -33.586 18.807  -6.971  1.000 57.828  0 385  GLU A OE2   1 ? 
ATOM   2943 N N     . ARG A 1 387 ? -31.716 19.886  -13.345 1.000 30.554  0 386  ARG A N     1 ? 
ATOM   2944 C CA    . ARG A 1 387 ? -31.701 20.868  -14.415 1.000 34.718  0 386  ARG A CA    1 ? 
ATOM   2945 C C     . ARG A 1 387 ? -30.837 20.424  -15.596 1.000 29.987  0 386  ARG A C     1 ? 
ATOM   2946 O O     . ARG A 1 387 ? -30.898 21.035  -16.651 1.000 28.342  0 386  ARG A O     1 ? 
ATOM   2947 C CB    . ARG A 1 387 ? -31.138 22.143  -13.765 1.000 47.539  0 386  ARG A CB    1 ? 
ATOM   2948 C CG    . ARG A 1 387 ? -31.651 23.513  -14.195 1.000 69.877  0 386  ARG A CG    1 ? 
ATOM   2949 C CD    . ARG A 1 387 ? -30.673 24.426  -14.986 1.000 84.567  0 386  ARG A CD    1 ? 
ATOM   2950 N NE    . ARG A 1 387 ? -30.421 24.038  -16.383 1.000 96.805  0 386  ARG A NE    1 ? 
ATOM   2951 C CZ    . ARG A 1 387 ? -29.881 24.793  -17.353 1.000 94.086  0 386  ARG A CZ    1 ? 
ATOM   2952 N NH1   . ARG A 1 387 ? -29.732 24.288  -18.570 1.000 91.608  0 386  ARG A NH1   1 ? 
ATOM   2953 N NH2   . ARG A 1 387 ? -29.502 26.041  -17.117 1.000 91.940  0 386  ARG A NH2   1 ? 
ATOM   2954 N N     . PHE A 1 388 ? -29.985 19.402  -15.412 1.000 26.190  0 387  PHE A N     1 ? 
ATOM   2955 C CA    . PHE A 1 388 ? -29.116 18.897  -16.461 1.000 25.686  0 387  PHE A CA    1 ? 
ATOM   2956 C C     . PHE A 1 388 ? -29.204 17.376  -16.553 1.000 24.593  0 387  PHE A C     1 ? 
ATOM   2957 O O     . PHE A 1 388 ? -29.165 16.682  -15.544 1.000 24.126  0 387  PHE A O     1 ? 
ATOM   2958 C CB    . PHE A 1 388 ? -27.629 19.188  -16.231 1.000 26.764  0 387  PHE A CB    1 ? 
ATOM   2959 C CG    . PHE A 1 388 ? -27.337 20.657  -16.454 1.000 27.142  0 387  PHE A CG    1 ? 
ATOM   2960 C CD1   . PHE A 1 388 ? -27.069 21.117  -17.728 1.000 27.278  0 387  PHE A CD1   1 ? 
ATOM   2961 C CD2   . PHE A 1 388 ? -27.418 21.563  -15.409 1.000 28.368  0 387  PHE A CD2   1 ? 
ATOM   2962 C CE1   . PHE A 1 388 ? -26.824 22.468  -17.944 1.000 33.329  0 387  PHE A CE1   1 ? 
ATOM   2963 C CE2   . PHE A 1 388 ? -27.150 22.906  -15.627 1.000 31.197  0 387  PHE A CE2   1 ? 
ATOM   2964 C CZ    . PHE A 1 388 ? -26.903 23.354  -16.904 1.000 30.079  0 387  PHE A CZ    1 ? 
ATOM   2965 N N     . ALA A 1 389 ? -29.343 16.888  -17.775 1.000 24.421  0 388  ALA A N     1 ? 
ATOM   2966 C CA    . ALA A 1 389 ? -29.174 15.480  -18.071 1.000 26.281  0 388  ALA A CA    1 ? 
ATOM   2967 C C     . ALA A 1 389 ? -27.695 15.134  -17.885 1.000 26.144  0 388  ALA A C     1 ? 
ATOM   2968 O O     . ALA A 1 389 ? -26.831 16.004  -18.003 1.000 24.801  0 388  ALA A O     1 ? 
ATOM   2969 C CB    . ALA A 1 389 ? -29.615 15.214  -19.481 1.000 28.139  0 388  ALA A CB    1 ? 
ATOM   2970 N N     . ASP A 1 390 ? -27.433 13.872  -17.562 1.000 26.343  0 389  ASP A N     1 ? 
ATOM   2971 C CA    . ASP A 1 390 ? -26.063 13.410  -17.389 1.000 26.232  0 389  ASP A CA    1 ? 
ATOM   2972 C C     . ASP A 1 390 ? -25.274 13.587  -18.682 1.000 24.711  0 389  ASP A C     1 ? 
ATOM   2973 O O     . ASP A 1 390 ? -25.523 12.916  -19.675 1.000 19.939  0 389  ASP A O     1 ? 
ATOM   2974 C CB    . ASP A 1 390 ? -26.046 11.950  -16.991 1.000 26.243  0 389  ASP A CB    1 ? 
ATOM   2975 C CG    . ASP A 1 390 ? -24.680 11.403  -16.632 1.000 26.822  0 389  ASP A CG    1 ? 
ATOM   2976 O OD1   . ASP A 1 390 ? -23.673 12.167  -16.708 1.000 23.273  0 389  ASP A OD1   1 ? 
ATOM   2977 O OD2   . ASP A 1 390 ? -24.638 10.233  -16.293 1.000 25.987  0 389  ASP A OD2   1 ? 
ATOM   2978 N N     . PRO A 1 391 ? -24.234 14.439  -18.707 1.000 21.900  0 390  PRO A N     1 ? 
ATOM   2979 C CA    . PRO A 1 391 ? -23.474 14.645  -19.941 1.000 20.587  0 390  PRO A CA    1 ? 
ATOM   2980 C C     . PRO A 1 391 ? -22.375 13.592  -20.148 1.000 19.677  0 390  PRO A C     1 ? 
ATOM   2981 O O     . PRO A 1 391 ? -21.708 13.595  -21.176 1.000 18.993  0 390  PRO A O     1 ? 
ATOM   2982 C CB    . PRO A 1 391 ? -22.942 16.059  -19.786 1.000 23.116  0 390  PRO A CB    1 ? 
ATOM   2983 C CG    . PRO A 1 391 ? -22.983 16.348  -18.315 1.000 25.149  0 390  PRO A CG    1 ? 
ATOM   2984 C CD    . PRO A 1 391 ? -23.840 15.335  -17.606 1.000 22.011  0 390  PRO A CD    1 ? 
ATOM   2985 N N     . SER A 1 392 ? -22.221 12.686  -19.167 1.000 19.424  0 391  SER A N     1 ? 
ATOM   2986 C CA    . SER A 1 392 ? -21.241 11.601  -19.204 1.000 20.185  0 391  SER A CA    1 ? 
ATOM   2987 C C     . SER A 1 392 ? -21.857 10.359  -19.842 1.000 19.711  0 391  SER A C     1 ? 
ATOM   2988 O O     . SER A 1 392 ? -23.070 10.236  -19.941 1.000 19.742  0 391  SER A O     1 ? 
ATOM   2989 C CB    . SER A 1 392 ? -20.740 11.253  -17.810 1.000 20.970  0 391  SER A CB    1 ? 
ATOM   2990 O OG    . SER A 1 392 ? -21.676 10.417  -17.141 1.000 21.642  0 391  SER A OG    1 ? 
ATOM   2991 N N     . PRO A 1 393 ? -21.030 9.361   -20.208 1.000 21.726  0 392  PRO A N     1 ? 
ATOM   2992 C CA    . PRO A 1 393 ? -21.527 8.053   -20.660 1.000 21.797  0 392  PRO A CA    1 ? 
ATOM   2993 C C     . PRO A 1 393 ? -22.311 7.261   -19.616 1.000 21.846  0 392  PRO A C     1 ? 
ATOM   2994 O O     . PRO A 1 393 ? -22.971 6.306   -19.946 1.000 21.501  0 392  PRO A O     1 ? 
ATOM   2995 C CB    . PRO A 1 393 ? -20.255 7.264   -21.005 1.000 23.364  0 392  PRO A CB    1 ? 
ATOM   2996 C CG    . PRO A 1 393 ? -19.176 8.274   -21.137 1.000 22.745  0 392  PRO A CG    1 ? 
ATOM   2997 C CD    . PRO A 1 393 ? -19.562 9.488   -20.326 1.000 20.632  0 392  PRO A CD    1 ? 
ATOM   2998 N N     . GLY A 1 394 ? -22.164 7.598   -18.345 1.000 22.278  0 393  GLY A N     1 ? 
ATOM   2999 C CA    . GLY A 1 394 ? -22.825 6.843   -17.291 1.000 22.598  0 393  GLY A CA    1 ? 
ATOM   3000 C C     . GLY A 1 394 ? -21.795 6.027   -16.544 1.000 24.546  0 393  GLY A C     1 ? 
ATOM   3001 O O     . GLY A 1 394 ? -20.656 6.477   -16.391 1.000 25.519  0 393  GLY A O     1 ? 
ATOM   3002 N N     . GLU A 1 395 ? -22.190 4.805   -16.157 1.000 21.416  0 394  GLU A N     1 ? 
ATOM   3003 C CA    . GLU A 1 395 ? -21.435 3.993   -15.228 1.000 24.684  0 394  GLU A CA    1 ? 
ATOM   3004 C C     . GLU A 1 395 ? -20.011 3.749   -15.724 1.000 20.854  0 394  GLU A C     1 ? 
ATOM   3005 O O     . GLU A 1 395 ? -19.772 3.456   -16.906 1.000 22.230  0 394  GLU A O     1 ? 
ATOM   3006 C CB    . GLU A 1 395 ? -22.153 2.663   -15.020 1.000 28.794  0 394  GLU A CB    1 ? 
ATOM   3007 C CG    . GLU A 1 395 ? -21.569 1.819   -13.895 1.000 34.558  0 394  GLU A CG    1 ? 
ATOM   3008 C CD    . GLU A 1 395 ? -22.225 0.448   -13.792 1.000 43.953  0 394  GLU A CD    1 ? 
ATOM   3009 O OE1   . GLU A 1 395 ? -23.129 0.164   -14.619 1.000 47.035  0 394  GLU A OE1   1 ? 
ATOM   3010 O OE2   . GLU A 1 395 ? -21.832 -0.339  -12.888 1.000 51.083  0 394  GLU A OE2   1 ? 
ATOM   3011 N N     . GLY A 1 396 ? -19.083 3.925   -14.784 1.000 20.790  0 395  GLY A N     1 ? 
ATOM   3012 C CA    . GLY A 1 396 ? -17.655 3.719   -15.005 1.000 20.292  0 395  GLY A CA    1 ? 
ATOM   3013 C C     . GLY A 1 396 ? -16.942 4.938   -15.597 1.000 19.998  0 395  GLY A C     1 ? 
ATOM   3014 O O     . GLY A 1 396 ? -15.723 4.892   -15.740 1.000 19.264  0 395  GLY A O     1 ? 
ATOM   3015 N N     . ALA A 1 397 ? -17.673 6.011   -15.922 1.000 19.277  0 396  ALA A N     1 ? 
ATOM   3016 C CA    . ALA A 1 397 ? -17.093 7.243   -16.446 1.000 19.289  0 396  ALA A CA    1 ? 
ATOM   3017 C C     . ALA A 1 397 ? -17.310 8.382   -15.449 1.000 21.024  0 396  ALA A C     1 ? 
ATOM   3018 O O     . ALA A 1 397 ? -18.298 8.419   -14.727 1.000 22.201  0 396  ALA A O     1 ? 
ATOM   3019 C CB    . ALA A 1 397 ? -17.692 7.570   -17.768 1.000 18.690  0 396  ALA A CB    1 ? 
ATOM   3020 N N     . GLY A 1 398 ? -16.371 9.320   -15.405 1.000 21.924  0 397  GLY A N     1 ? 
ATOM   3021 C CA    . GLY A 1 398 ? -16.478 10.434  -14.477 1.000 20.396  0 397  GLY A CA    1 ? 
ATOM   3022 C C     . GLY A 1 398 ? -17.113 11.654  -15.123 1.000 19.479  0 397  GLY A C     1 ? 
ATOM   3023 O O     . GLY A 1 398 ? -17.198 11.749  -16.342 1.000 20.353  0 397  GLY A O     1 ? 
ATOM   3024 N N     . HIS A 1 399 ? -17.512 12.606  -14.275 1.000 18.560  0 398  HIS A N     1 ? 
ATOM   3025 C CA    . HIS A 1 399 ? -17.753 13.982  -14.679 1.000 17.935  0 398  HIS A CA    1 ? 
ATOM   3026 C C     . HIS A 1 399 ? -16.479 14.840  -14.555 1.000 17.577  0 398  HIS A C     1 ? 
ATOM   3027 O O     . HIS A 1 399 ? -16.280 15.807  -15.296 1.000 17.500  0 398  HIS A O     1 ? 
ATOM   3028 C CB    . HIS A 1 399 ? -18.830 14.575  -13.767 1.000 18.360  0 398  HIS A CB    1 ? 
ATOM   3029 C CG    . HIS A 1 399 ? -20.117 13.858  -13.877 1.000 19.313  0 398  HIS A CG    1 ? 
ATOM   3030 N ND1   . HIS A 1 399 ? -20.673 13.149  -12.832 1.000 19.507  0 398  HIS A ND1   1 ? 
ATOM   3031 C CD2   . HIS A 1 399 ? -20.947 13.717  -14.942 1.000 19.553  0 398  HIS A CD2   1 ? 
ATOM   3032 C CE1   . HIS A 1 399 ? -21.812 12.621  -13.258 1.000 18.914  0 398  HIS A CE1   1 ? 
ATOM   3033 N NE2   . HIS A 1 399 ? -21.973 12.929  -14.558 1.000 18.641  0 398  HIS A NE2   1 ? 
ATOM   3034 N N     . ILE A 1 400 ? -15.639 14.465  -13.599 1.000 16.618  0 399  ILE A N     1 ? 
ATOM   3035 C CA    . ILE A 1 400 ? -14.446 15.185  -13.185 1.000 18.322  0 399  ILE A CA    1 ? 
ATOM   3036 C C     . ILE A 1 400 ? -13.244 14.252  -13.317 1.000 18.159  0 399  ILE A C     1 ? 
ATOM   3037 O O     . ILE A 1 400 ? -13.306 13.080  -12.939 1.000 19.379  0 399  ILE A O     1 ? 
ATOM   3038 C CB    . ILE A 1 400 ? -14.596 15.603  -11.706 1.000 20.205  0 399  ILE A CB    1 ? 
ATOM   3039 C CG1   . ILE A 1 400 ? -15.669 16.668  -11.513 1.000 20.717  0 399  ILE A CG1   1 ? 
ATOM   3040 C CG2   . ILE A 1 400 ? -13.245 16.007  -11.099 1.000 22.560  0 399  ILE A CG2   1 ? 
ATOM   3041 C CD1   . ILE A 1 400 ? -16.046 16.902  -10.066 1.000 21.726  0 399  ILE A CD1   1 ? 
ATOM   3042 N N     . GLU A 1 401 ? -12.110 14.822  -13.724 1.000 18.047  0 400  GLU A N     1 ? 
ATOM   3043 C CA    . GLU A 1 401 ? -10.813 14.186  -13.620 1.000 17.587  0 400  GLU A CA    1 ? 
ATOM   3044 C C     . GLU A 1 401 ? -9.892  15.092  -12.818 1.000 21.006  0 400  GLU A C     1 ? 
ATOM   3045 O O     . GLU A 1 401 ? -9.941  16.305  -12.994 1.000 19.408  0 400  GLU A O     1 ? 
ATOM   3046 C CB    . GLU A 1 401 ? -10.230 13.915  -15.006 1.000 20.330  0 400  GLU A CB    1 ? 
ATOM   3047 C CG    . GLU A 1 401 ? -8.899  13.173  -14.962 1.000 22.305  0 400  GLU A CG    1 ? 
ATOM   3048 C CD    . GLU A 1 401 ? -8.249  13.045  -16.345 1.000 26.955  0 400  GLU A CD    1 ? 
ATOM   3049 O OE1   . GLU A 1 401 ? -8.744  13.662  -17.368 1.000 28.728  0 400  GLU A OE1   1 ? 
ATOM   3050 O OE2   . GLU A 1 401 ? -7.185  12.328  -16.397 1.000 27.096  0 400  GLU A OE2   1 ? 
ATOM   3051 N N     . LEU A 1 402 ? -9.146  14.477  -11.890 1.000 18.544  0 401  LEU A N     1 ? 
ATOM   3052 C CA    . LEU A 1 402 ? -8.080  15.118  -11.139 1.000 18.321  0 401  LEU A CA    1 ? 
ATOM   3053 C C     . LEU A 1 402 ? -6.779  14.491  -11.640 1.000 19.059  0 401  LEU A C     1 ? 
ATOM   3054 O O     . LEU A 1 402 ? -6.593  13.270  -11.600 1.000 19.340  0 401  LEU A O     1 ? 
ATOM   3055 C CB    . LEU A 1 402 ? -8.317  14.860  -9.643  1.000 17.138  0 401  LEU A CB    1 ? 
ATOM   3056 C CG    . LEU A 1 402 ? -9.604  15.414  -9.048  1.000 18.882  0 401  LEU A CG    1 ? 
ATOM   3057 C CD1   . LEU A 1 402 ? -9.616  15.124  -7.549  1.000 20.387  0 401  LEU A CD1   1 ? 
ATOM   3058 C CD2   . LEU A 1 402 ? -9.753  16.901  -9.226  1.000 18.960  0 401  LEU A CD2   1 ? 
ATOM   3059 N N     . ILE A 1 403 ? -5.903  15.319  -12.202 1.000 15.905  0 402  ILE A N     1 ? 
ATOM   3060 C CA    . ILE A 1 403 ? -4.623  14.864  -12.714 1.000 17.311  0 402  ILE A CA    1 ? 
ATOM   3061 C C     . ILE A 1 403 ? -3.521  15.304  -11.766 1.000 18.298  0 402  ILE A C     1 ? 
ATOM   3062 O O     . ILE A 1 403 ? -3.422  16.485  -11.446 1.000 16.800  0 402  ILE A O     1 ? 
ATOM   3063 C CB    . ILE A 1 403 ? -4.377  15.461  -14.110 1.000 18.035  0 402  ILE A CB    1 ? 
ATOM   3064 C CG1   . ILE A 1 403 ? -5.551  15.191  -15.056 1.000 19.250  0 402  ILE A CG1   1 ? 
ATOM   3065 C CG2   . ILE A 1 403 ? -3.044  14.964  -14.680 1.000 17.731  0 402  ILE A CG2   1 ? 
ATOM   3066 C CD1   . ILE A 1 403 ? -5.363  15.730  -16.465 1.000 20.424  0 402  ILE A CD1   1 ? 
ATOM   3067 N N     . LEU A 1 404 ? -2.698  14.346  -11.335 1.000 17.903  0 403  LEU A N     1 ? 
ATOM   3068 C CA    . LEU A 1 404 ? -1.596  14.620  -10.428 1.000 19.433  0 403  LEU A CA    1 ? 
ATOM   3069 C C     . LEU A 1 404 ? -0.338  14.774  -11.255 1.000 18.153  0 403  LEU A C     1 ? 
ATOM   3070 O O     . LEU A 1 404 ? -0.011  13.908  -12.079 1.000 17.366  0 403  LEU A O     1 ? 
ATOM   3071 C CB    . LEU A 1 404 ? -1.399  13.487  -9.426  1.000 19.315  0 403  LEU A CB    1 ? 
ATOM   3072 C CG    . LEU A 1 404 ? -2.640  13.039  -8.657  1.000 24.607  0 403  LEU A CG    1 ? 
ATOM   3073 C CD1   . LEU A 1 404 ? -2.273  11.874  -7.721  1.000 23.415  0 403  LEU A CD1   1 ? 
ATOM   3074 C CD2   . LEU A 1 404 ? -3.256  14.199  -7.906  1.000 24.828  0 403  LEU A CD2   1 ? 
ATOM   3075 N N     . SER A 1 405 ? 0.374   15.873  -11.001 1.000 16.692  0 404  SER A N     1 ? 
ATOM   3076 C CA    . SER A 1 405 ? 1.625   16.175  -11.663 1.000 18.997  0 404  SER A CA    1 ? 
ATOM   3077 C C     . SER A 1 405 ? 2.697   16.525  -10.637 1.000 18.496  0 404  SER A C     1 ? 
ATOM   3078 O O     . SER A 1 405 ? 2.464   17.349  -9.743  1.000 17.596  0 404  SER A O     1 ? 
ATOM   3079 C CB    . SER A 1 405 ? 1.462   17.333  -12.640 1.000 21.556  0 404  SER A CB    1 ? 
ATOM   3080 O OG    . SER A 1 405 ? 0.580   16.995  -13.704 1.000 23.365  0 404  SER A OG    1 ? 
ATOM   3081 N N     . ASN A 1 406 ? 3.895   15.969  -10.864 1.000 18.428  0 405  ASN A N     1 ? 
ATOM   3082 C CA    . ASN A 1 406 ? 4.998   16.062  -9.930  1.000 18.068  0 405  ASN A CA    1 ? 
ATOM   3083 C C     . ASN A 1 406 ? 5.813   17.328  -10.183 1.000 19.533  0 405  ASN A C     1 ? 
ATOM   3084 O O     . ASN A 1 406 ? 7.048   17.275  -10.163 1.000 19.068  0 405  ASN A O     1 ? 
ATOM   3085 C CB    . ASN A 1 406 ? 5.870   14.817  -10.010 1.000 15.612  0 405  ASN A CB    1 ? 
ATOM   3086 C CG    . ASN A 1 406 ? 7.004   14.815  -9.023  1.000 17.244  0 405  ASN A CG    1 ? 
ATOM   3087 O OD1   . ASN A 1 406 ? 6.835   15.246  -7.877  1.000 18.815  0 405  ASN A OD1   1 ? 
ATOM   3088 N ND2   . ASN A 1 406 ? 8.177   14.414  -9.471  1.000 16.962  0 405  ASN A ND2   1 ? 
ATOM   3089 N N     . GLN A 1 407 ? 5.116   18.436  -10.469 1.000 18.364  0 406  GLN A N     1 ? 
ATOM   3090 C CA    . GLN A 1 407 ? 5.728   19.752  -10.640 1.000 19.825  0 406  GLN A CA    1 ? 
ATOM   3091 C C     . GLN A 1 407 ? 4.599   20.780  -10.733 1.000 18.626  0 406  GLN A C     1 ? 
ATOM   3092 O O     . GLN A 1 407 ? 3.418   20.413  -10.711 1.000 17.530  0 406  GLN A O     1 ? 
ATOM   3093 C CB    . GLN A 1 407 ? 6.564   19.824  -11.930 1.000 19.040  0 406  GLN A CB    1 ? 
ATOM   3094 C CG    . GLN A 1 407 ? 5.717   19.751  -13.199 1.000 21.270  0 406  GLN A CG    1 ? 
ATOM   3095 C CD    . GLN A 1 407 ? 6.527   19.570  -14.455 1.000 23.699  0 406  GLN A CD    1 ? 
ATOM   3096 O OE1   . GLN A 1 407 ? 6.220   18.717  -15.310 1.000 24.208  0 406  GLN A OE1   1 ? 
ATOM   3097 N NE2   . GLN A 1 407 ? 7.529   20.438  -14.600 1.000 22.463  0 406  GLN A NE2   1 ? 
ATOM   3098 N N     . TRP A 1 408 ? 4.979   22.072  -10.800 1.000 17.437  0 407  TRP A N     1 ? 
ATOM   3099 C CA    . TRP A 1 408 ? 4.096   23.129  -11.246 1.000 18.142  0 407  TRP A CA    1 ? 
ATOM   3100 C C     . TRP A 1 408 ? 3.941   23.005  -12.753 1.000 17.365  0 407  TRP A C     1 ? 
ATOM   3101 O O     . TRP A 1 408 ? 4.861   23.352  -13.486 1.000 19.673  0 407  TRP A O     1 ? 
ATOM   3102 C CB    . TRP A 1 408 ? 4.678   24.504  -10.913 1.000 18.466  0 407  TRP A CB    1 ? 
ATOM   3103 C CG    . TRP A 1 408 ? 3.786   25.675  -11.223 1.000 17.646  0 407  TRP A CG    1 ? 
ATOM   3104 C CD1   . TRP A 1 408 ? 3.373   26.119  -12.448 1.000 15.549  0 407  TRP A CD1   1 ? 
ATOM   3105 C CD2   . TRP A 1 408 ? 3.309   26.632  -10.266 1.000 17.552  0 407  TRP A CD2   1 ? 
ATOM   3106 N NE1   . TRP A 1 408 ? 2.586   27.225  -12.300 1.000 15.719  0 407  TRP A NE1   1 ? 
ATOM   3107 C CE2   . TRP A 1 408 ? 2.561   27.587  -10.978 1.000 17.761  0 407  TRP A CE2   1 ? 
ATOM   3108 C CE3   . TRP A 1 408 ? 3.465   26.779  -8.884  1.000 20.335  0 407  TRP A CE3   1 ? 
ATOM   3109 C CZ2   . TRP A 1 408 ? 1.960   28.666  -10.350 1.000 17.900  0 407  TRP A CZ2   1 ? 
ATOM   3110 C CZ3   . TRP A 1 408 ? 2.892   27.862  -8.268  1.000 19.536  0 407  TRP A CZ3   1 ? 
ATOM   3111 C CH2   . TRP A 1 408 ? 2.117   28.768  -8.987  1.000 19.789  0 407  TRP A CH2   1 ? 
ATOM   3112 N N     . THR A 1 409 ? 2.792   22.486  -13.205 1.000 17.146  0 408  THR A N     1 ? 
ATOM   3113 C CA    . THR A 1 409 ? 2.569   22.368  -14.636 1.000 20.454  0 408  THR A CA    1 ? 
ATOM   3114 C C     . THR A 1 409 ? 2.226   23.765  -15.147 1.000 20.241  0 408  THR A C     1 ? 
ATOM   3115 O O     . THR A 1 409 ? 1.237   24.332  -14.701 1.000 21.376  0 408  THR A O     1 ? 
ATOM   3116 C CB    . THR A 1 409 ? 1.418   21.414  -14.968 1.000 19.368  0 408  THR A CB    1 ? 
ATOM   3117 O OG1   . THR A 1 409 ? 1.596   20.201  -14.254 1.000 20.772  0 408  THR A OG1   1 ? 
ATOM   3118 C CG2   . THR A 1 409 ? 1.345   21.130  -16.463 1.000 20.909  0 408  THR A CG2   1 ? 
ATOM   3119 N N     . PRO A 1 410 ? 2.970   24.336  -16.112 1.000 22.693  0 409  PRO A N     1 ? 
ATOM   3120 C CA    . PRO A 1 410 ? 2.595   25.643  -16.652 1.000 22.892  0 409  PRO A CA    1 ? 
ATOM   3121 C C     . PRO A 1 410 ? 1.261   25.540  -17.385 1.000 22.379  0 409  PRO A C     1 ? 
ATOM   3122 O O     . PRO A 1 410 ? 1.034   24.602  -18.137 1.000 22.640  0 409  PRO A O     1 ? 
ATOM   3123 C CB    . PRO A 1 410 ? 3.763   26.010  -17.569 1.000 24.804  0 409  PRO A CB    1 ? 
ATOM   3124 C CG    . PRO A 1 410 ? 4.334   24.668  -17.989 1.000 25.278  0 409  PRO A CG    1 ? 
ATOM   3125 C CD    . PRO A 1 410 ? 4.144   23.754  -16.773 1.000 23.342  0 409  PRO A CD    1 ? 
ATOM   3126 N N     . GLU A 1 411 ? 0.366   26.489  -17.128 1.000 23.702  0 410  GLU A N     1 ? 
ATOM   3127 C CA    . GLU A 1 411 ? -0.872  26.649  -17.871 1.000 23.906  0 410  GLU A CA    1 ? 
ATOM   3128 C C     . GLU A 1 411 ? -1.038  28.147  -18.090 1.000 24.323  0 410  GLU A C     1 ? 
ATOM   3129 O O     . GLU A 1 411 ? -0.305  28.729  -18.873 1.000 24.824  0 410  GLU A O     1 ? 
ATOM   3130 C CB    . GLU A 1 411 ? -2.032  26.007  -17.119 1.000 26.340  0 410  GLU A CB    1 ? 
ATOM   3131 C CG    . GLU A 1 411 ? -2.117  24.512  -17.376 1.000 32.285  0 410  GLU A CG    1 ? 
ATOM   3132 C CD    . GLU A 1 411 ? -3.189  23.783  -16.584 1.000 32.456  0 410  GLU A CD    1 ? 
ATOM   3133 O OE1   . GLU A 1 411 ? -4.084  24.417  -15.970 1.000 31.069  0 410  GLU A OE1   1 ? 
ATOM   3134 O OE2   . GLU A 1 411 ? -3.054  22.538  -16.577 1.000 30.352  0 410  GLU A OE2   1 ? 
ATOM   3135 N N     . VAL A 1 412 ? -1.852  28.781  -17.258 1.000 21.226  0 411  VAL A N     1 ? 
ATOM   3136 C CA    . VAL A 1 412 ? -1.976  30.224  -17.279 1.000 23.511  0 411  VAL A CA    1 ? 
ATOM   3137 C C     . VAL A 1 412 ? -0.734  30.808  -16.629 1.000 24.611  0 411  VAL A C     1 ? 
ATOM   3138 O O     . VAL A 1 412 ? -0.187  31.771  -17.127 1.000 21.076  0 411  VAL A O     1 ? 
ATOM   3139 C CB    . VAL A 1 412 ? -3.226  30.697  -16.524 1.000 22.311  0 411  VAL A CB    1 ? 
ATOM   3140 C CG1   . VAL A 1 412 ? -3.225  32.204  -16.344 1.000 26.077  0 411  VAL A CG1   1 ? 
ATOM   3141 C CG2   . VAL A 1 412 ? -4.469  30.203  -17.228 1.000 25.149  0 411  VAL A CG2   1 ? 
ATOM   3142 N N     . GLN A 1 413 ? -0.339  30.222  -15.498 1.000 20.498  0 412  GLN A N     1 ? 
ATOM   3143 C CA    . GLN A 1 413 ? 0.857   30.636  -14.796 1.000 20.853  0 412  GLN A CA    1 ? 
ATOM   3144 C C     . GLN A 1 413 ? 1.988   29.628  -14.951 1.000 22.449  0 412  GLN A C     1 ? 
ATOM   3145 O O     . GLN A 1 413 ? 1.759   28.412  -15.022 1.000 20.504  0 412  GLN A O     1 ? 
ATOM   3146 C CB    . GLN A 1 413 ? 0.579   30.701  -13.294 1.000 20.496  0 412  GLN A CB    1 ? 
ATOM   3147 C CG    . GLN A 1 413 ? -0.430  31.761  -12.888 1.000 22.342  0 412  GLN A CG    1 ? 
ATOM   3148 C CD    . GLN A 1 413 ? -0.661  31.771  -11.390 1.000 23.930  0 412  GLN A CD    1 ? 
ATOM   3149 O OE1   . GLN A 1 413 ? -1.229  30.834  -10.811 1.000 20.321  0 412  GLN A OE1   1 ? 
ATOM   3150 N NE2   . GLN A 1 413 ? -0.221  32.843  -10.759 1.000 26.332  0 412  GLN A NE2   1 ? 
ATOM   3151 N N     . ILE A 1 414 ? 3.213   30.149  -14.892 1.000 20.078  0 413  ILE A N     1 ? 
ATOM   3152 C CA    . ILE A 1 414 ? 4.409   29.322  -14.880 1.000 21.660  0 413  ILE A CA    1 ? 
ATOM   3153 C C     . ILE A 1 414 ? 4.956   29.297  -13.462 1.000 19.932  0 413  ILE A C     1 ? 
ATOM   3154 O O     . ILE A 1 414 ? 4.582   30.113  -12.612 1.000 18.340  0 413  ILE A O     1 ? 
ATOM   3155 C CB    . ILE A 1 414 ? 5.455   29.762  -15.921 1.000 25.990  0 413  ILE A CB    1 ? 
ATOM   3156 C CG1   . ILE A 1 414 ? 6.110   31.083  -15.574 1.000 30.164  0 413  ILE A CG1   1 ? 
ATOM   3157 C CG2   . ILE A 1 414 ? 4.833   29.792  -17.320 1.000 29.157  0 413  ILE A CG2   1 ? 
ATOM   3158 C CD1   . ILE A 1 414 ? 7.289   31.440  -16.460 1.000 33.576  0 413  ILE A CD1   1 ? 
ATOM   3159 N N     . PRO A 1 415 ? 5.826   28.310  -13.160 1.000 21.771  0 414  PRO A N     1 ? 
ATOM   3160 C CA    . PRO A 1 415 ? 6.372   28.154  -11.814 1.000 22.756  0 414  PRO A CA    1 ? 
ATOM   3161 C C     . PRO A 1 415 ? 7.148   29.386  -11.371 1.000 23.003  0 414  PRO A C     1 ? 
ATOM   3162 O O     . PRO A 1 415 ? 7.882   30.002  -12.140 1.000 20.634  0 414  PRO A O     1 ? 
ATOM   3163 C CB    . PRO A 1 415 ? 7.335   26.957  -11.884 1.000 25.055  0 414  PRO A CB    1 ? 
ATOM   3164 C CG    . PRO A 1 415 ? 7.115   26.346  -13.240 1.000 25.117  0 414  PRO A CG    1 ? 
ATOM   3165 C CD    . PRO A 1 415 ? 6.340   27.305  -14.097 1.000 24.039  0 414  PRO A CD    1 ? 
ATOM   3166 N N     . PRO A 1 416 ? 7.029   29.728  -10.088 1.000 22.656  0 415  PRO A N     1 ? 
ATOM   3167 C CA    . PRO A 1 416 ? 7.970   30.636  -9.431  1.000 24.177  0 415  PRO A CA    1 ? 
ATOM   3168 C C     . PRO A 1 416 ? 9.403   30.110  -9.493  1.000 21.266  0 415  PRO A C     1 ? 
ATOM   3169 O O     . PRO A 1 416 ? 9.612   28.905  -9.620  1.000 21.222  0 415  PRO A O     1 ? 
ATOM   3170 C CB    . PRO A 1 416 ? 7.493   30.669  -7.977  1.000 25.098  0 415  PRO A CB    1 ? 
ATOM   3171 C CG    . PRO A 1 416 ? 6.129   30.011  -7.956  1.000 26.913  0 415  PRO A CG    1 ? 
ATOM   3172 C CD    . PRO A 1 416 ? 5.972   29.203  -9.211  1.000 25.686  0 415  PRO A CD    1 ? 
ATOM   3173 N N     . ALA A 1 417 ? 10.392  31.002  -9.348  1.000 24.187  0 416  ALA A N     1 ? 
ATOM   3174 C CA    . ALA A 1 417 ? 11.792  30.634  -9.536  1.000 22.170  0 416  ALA A CA    1 ? 
ATOM   3175 C C     . ALA A 1 417 ? 12.255  29.692  -8.436  1.000 21.865  0 416  ALA A C     1 ? 
ATOM   3176 O O     . ALA A 1 417 ? 13.248  28.985  -8.634  1.000 21.889  0 416  ALA A O     1 ? 
ATOM   3177 C CB    . ALA A 1 417 ? 12.707  31.848  -9.563  1.000 23.664  0 416  ALA A CB    1 ? 
ATOM   3178 N N     . THR A 1 418 ? 11.615  29.802  -7.274  1.000 22.458  0 417  THR A N     1 ? 
ATOM   3179 C CA    . THR A 1 418 ? 11.986  29.048  -6.087  1.000 24.095  0 417  THR A CA    1 ? 
ATOM   3180 C C     . THR A 1 418 ? 10.798  28.194  -5.637  1.000 21.629  0 417  THR A C     1 ? 
ATOM   3181 O O     . THR A 1 418 ? 9.658   28.618  -5.737  1.000 23.830  0 417  THR A O     1 ? 
ATOM   3182 C CB    . THR A 1 418 ? 12.394  30.031  -4.984  1.000 28.325  0 417  THR A CB    1 ? 
ATOM   3183 O OG1   . THR A 1 418 ? 13.527  30.754  -5.476  1.000 33.425  0 417  THR A OG1   1 ? 
ATOM   3184 C CG2   . THR A 1 418 ? 12.864  29.320  -3.728  1.000 35.223  0 417  THR A CG2   1 ? 
ATOM   3185 N N     . GLY A 1 419 ? 11.099  27.030  -5.042  1.000 22.578  0 418  GLY A N     1 ? 
ATOM   3186 C CA    . GLY A 1 419 ? 10.097  26.170  -4.444  1.000 21.608  0 418  GLY A CA    1 ? 
ATOM   3187 C C     . GLY A 1 419 ? 9.828   24.930  -5.290  1.000 21.719  0 418  GLY A C     1 ? 
ATOM   3188 O O     . GLY A 1 419 ? 10.200  24.851  -6.472  1.000 21.564  0 418  GLY A O     1 ? 
ATOM   3189 N N     . SER A 1 420 ? 9.118   23.990  -4.647  1.000 21.397  0 419  SER A N     1 ? 
ATOM   3190 C CA    . SER A 1 420 ? 8.761   22.694  -5.193  1.000 19.887  0 419  SER A CA    1 ? 
ATOM   3191 C C     . SER A 1 420 ? 7.256   22.553  -5.117  1.000 18.823  0 419  SER A C     1 ? 
ATOM   3192 O O     . SER A 1 420 ? 6.653   23.032  -4.163  1.000 20.068  0 419  SER A O     1 ? 
ATOM   3193 C CB    . SER A 1 420 ? 9.455   21.569  -4.456  1.000 20.771  0 419  SER A CB    1 ? 
ATOM   3194 O OG    . SER A 1 420 ? 10.847  21.733  -4.615  1.000 21.912  0 419  SER A OG    1 ? 
ATOM   3195 N N     . PHE A 1 421 ? 6.664   21.952  -6.157  1.000 17.332  0 420  PHE A N     1 ? 
ATOM   3196 C CA    . PHE A 1 421 ? 5.219   22.001  -6.318  1.000 17.100  0 420  PHE A CA    1 ? 
ATOM   3197 C C     . PHE A 1 421 ? 4.652   20.670  -6.791  1.000 17.476  0 420  PHE A C     1 ? 
ATOM   3198 O O     . PHE A 1 421 ? 5.312   19.878  -7.462  1.000 17.802  0 420  PHE A O     1 ? 
ATOM   3199 C CB    . PHE A 1 421 ? 4.836   23.149  -7.270  1.000 17.601  0 420  PHE A CB    1 ? 
ATOM   3200 C CG    . PHE A 1 421 ? 5.380   24.507  -6.827  1.000 17.872  0 420  PHE A CG    1 ? 
ATOM   3201 C CD1   . PHE A 1 421 ? 4.694   25.284  -5.906  1.000 19.840  0 420  PHE A CD1   1 ? 
ATOM   3202 C CD2   . PHE A 1 421 ? 6.571   24.996  -7.349  1.000 20.475  0 420  PHE A CD2   1 ? 
ATOM   3203 C CE1   . PHE A 1 421 ? 5.195   26.487  -5.482  1.000 21.939  0 420  PHE A CE1   1 ? 
ATOM   3204 C CE2   . PHE A 1 421 ? 7.078   26.222  -6.940  1.000 20.314  0 420  PHE A CE2   1 ? 
ATOM   3205 C CZ    . PHE A 1 421 ? 6.390   26.969  -6.012  1.000 22.713  0 420  PHE A CZ    1 ? 
ATOM   3206 N N     . LEU A 1 422 ? 3.370   20.500  -6.440  1.000 18.918  0 421  LEU A N     1 ? 
ATOM   3207 C CA    . LEU A 1 422 ? 2.465   19.492  -6.953  1.000 18.648  0 421  LEU A CA    1 ? 
ATOM   3208 C C     . LEU A 1 422 ? 1.374   20.235  -7.692  1.000 17.849  0 421  LEU A C     1 ? 
ATOM   3209 O O     . LEU A 1 422 ? 0.902   21.235  -7.194  1.000 18.062  0 421  LEU A O     1 ? 
ATOM   3210 C CB    . LEU A 1 422 ? 1.866   18.785  -5.724  1.000 19.878  0 421  LEU A CB    1 ? 
ATOM   3211 C CG    . LEU A 1 422 ? 0.531   18.062  -5.918  1.000 20.804  0 421  LEU A CG    1 ? 
ATOM   3212 C CD1   . LEU A 1 422 ? 0.659   16.870  -6.862  1.000 21.584  0 421  LEU A CD1   1 ? 
ATOM   3213 C CD2   . LEU A 1 422 ? -0.047  17.586  -4.611  1.000 23.746  0 421  LEU A CD2   1 ? 
ATOM   3214 N N     . THR A 1 423 ? 0.907   19.714  -8.823  1.000 16.461  0 422  THR A N     1 ? 
ATOM   3215 C CA    . THR A 1 423 ? -0.286  20.270  -9.417  1.000 15.860  0 422  THR A CA    1 ? 
ATOM   3216 C C     . THR A 1 423 ? -1.358  19.189  -9.362  1.000 17.352  0 422  THR A C     1 ? 
ATOM   3217 O O     . THR A 1 423 ? -1.089  18.058  -9.749  1.000 17.689  0 422  THR A O     1 ? 
ATOM   3218 C CB    . THR A 1 423 ? -0.049  20.693  -10.869 1.000 16.480  0 422  THR A CB    1 ? 
ATOM   3219 O OG1   . THR A 1 423 ? 1.080   21.567  -10.972 1.000 16.945  0 422  THR A OG1   1 ? 
ATOM   3220 C CG2   . THR A 1 423 ? -1.273  21.430  -11.407 1.000 17.810  0 422  THR A CG2   1 ? 
ATOM   3221 N N     . VAL A 1 424 ? -2.565  19.561  -8.910  1.000 17.408  0 423  VAL A N     1 ? 
ATOM   3222 C CA    . VAL A 1 424 ? -3.734  18.735  -9.126  1.000 18.441  0 423  VAL A CA    1 ? 
ATOM   3223 C C     . VAL A 1 424 ? -4.635  19.476  -10.105 1.000 16.609  0 423  VAL A C     1 ? 
ATOM   3224 O O     . VAL A 1 424 ? -5.208  20.516  -9.787  1.000 18.128  0 423  VAL A O     1 ? 
ATOM   3225 C CB    . VAL A 1 424 ? -4.459  18.385  -7.823  1.000 18.796  0 423  VAL A CB    1 ? 
ATOM   3226 C CG1   . VAL A 1 424 ? -5.568  17.397  -8.131  1.000 20.788  0 423  VAL A CG1   1 ? 
ATOM   3227 C CG2   . VAL A 1 424 ? -3.509  17.854  -6.751  1.000 18.914  0 423  VAL A CG2   1 ? 
ATOM   3228 N N     . HIS A 1 425 ? -4.670  19.006  -11.356 1.000 16.630  0 424  HIS A N     1 ? 
ATOM   3229 C CA    . HIS A 1 425 ? -5.476  19.661  -12.374 1.000 16.289  0 424  HIS A CA    1 ? 
ATOM   3230 C C     . HIS A 1 425 ? -6.921  19.217  -12.208 1.000 17.940  0 424  HIS A C     1 ? 
ATOM   3231 O O     . HIS A 1 425 ? -7.168  18.030  -12.072 1.000 19.310  0 424  HIS A O     1 ? 
ATOM   3232 C CB    . HIS A 1 425 ? -5.012  19.306  -13.792 1.000 18.463  0 424  HIS A CB    1 ? 
ATOM   3233 C CG    . HIS A 1 425 ? -3.564  19.570  -14.050 1.000 19.245  0 424  HIS A CG    1 ? 
ATOM   3234 N ND1   . HIS A 1 425 ? -3.131  20.723  -14.679 1.000 21.608  0 424  HIS A ND1   1 ? 
ATOM   3235 C CD2   . HIS A 1 425 ? -2.470  18.844  -13.812 1.000 24.071  0 424  HIS A CD2   1 ? 
ATOM   3236 C CE1   . HIS A 1 425 ? -1.819  20.679  -14.783 1.000 22.678  0 424  HIS A CE1   1 ? 
ATOM   3237 N NE2   . HIS A 1 425 ? -1.394  19.541  -14.289 1.000 22.691  0 424  HIS A NE2   1 ? 
ATOM   3238 N N     . ALA A 1 426 ? -7.850  20.173  -12.228 1.000 17.311  0 425  ALA A N     1 ? 
ATOM   3239 C CA    . ALA A 1 426 ? -9.288  19.922  -12.231 1.000 16.445  0 425  ALA A CA    1 ? 
ATOM   3240 C C     . ALA A 1 426 ? -9.791  19.971  -13.676 1.000 18.222  0 425  ALA A C     1 ? 
ATOM   3241 O O     . ALA A 1 426 ? -9.614  20.985  -14.330 1.000 17.682  0 425  ALA A O     1 ? 
ATOM   3242 C CB    . ALA A 1 426 ? -9.994  20.971  -11.424 1.000 16.704  0 425  ALA A CB    1 ? 
ATOM   3243 N N     . VAL A 1 427 ? -10.383 18.877  -14.175 1.000 18.578  0 426  VAL A N     1 ? 
ATOM   3244 C CA    . VAL A 1 427 ? -10.815 18.809  -15.556 1.000 16.924  0 426  VAL A CA    1 ? 
ATOM   3245 C C     . VAL A 1 427 ? -12.301 18.454  -15.532 1.000 17.265  0 426  VAL A C     1 ? 
ATOM   3246 O O     . VAL A 1 427 ? -12.707 17.540  -14.819 1.000 16.271  0 426  VAL A O     1 ? 
ATOM   3247 C CB    . VAL A 1 427 ? -10.050 17.775  -16.395 1.000 16.830  0 426  VAL A CB    1 ? 
ATOM   3248 C CG1   . VAL A 1 427 ? -10.492 17.741  -17.860 1.000 17.436  0 426  VAL A CG1   1 ? 
ATOM   3249 C CG2   . VAL A 1 427 ? -8.551  17.995  -16.304 1.000 18.867  0 426  VAL A CG2   1 ? 
ATOM   3250 N N     . VAL A 1 428 ? -13.110 19.152  -16.336 1.000 16.888  0 427  VAL A N     1 ? 
ATOM   3251 C CA    . VAL A 1 428 ? -14.460 18.662  -16.551 1.000 16.207  0 427  VAL A CA    1 ? 
ATOM   3252 C C     . VAL A 1 428 ? -14.424 17.741  -17.759 1.000 16.722  0 427  VAL A C     1 ? 
ATOM   3253 O O     . VAL A 1 428 ? -14.370 18.192  -18.909 1.000 16.875  0 427  VAL A O     1 ? 
ATOM   3254 C CB    . VAL A 1 428 ? -15.495 19.782  -16.739 1.000 18.575  0 427  VAL A CB    1 ? 
ATOM   3255 C CG1   . VAL A 1 428 ? -16.875 19.147  -16.895 1.000 19.179  0 427  VAL A CG1   1 ? 
ATOM   3256 C CG2   . VAL A 1 428 ? -15.439 20.760  -15.576 1.000 18.765  0 427  VAL A CG2   1 ? 
ATOM   3257 N N     . VAL A 1 429 ? -14.437 16.440  -17.513 1.000 17.135  0 428  VAL A N     1 ? 
ATOM   3258 C CA    . VAL A 1 429 ? -14.321 15.504  -18.627 1.000 17.619  0 428  VAL A CA    1 ? 
ATOM   3259 C C     . VAL A 1 429 ? -15.665 15.199  -19.308 1.000 20.066  0 428  VAL A C     1 ? 
ATOM   3260 O O     . VAL A 1 429 ? -15.675 14.629  -20.400 1.000 20.426  0 428  VAL A O     1 ? 
ATOM   3261 C CB    . VAL A 1 429 ? -13.611 14.204  -18.230 1.000 17.130  0 428  VAL A CB    1 ? 
ATOM   3262 C CG1   . VAL A 1 429 ? -12.136 14.452  -17.984 1.000 19.224  0 428  VAL A CG1   1 ? 
ATOM   3263 C CG2   . VAL A 1 429 ? -14.264 13.543  -17.033 1.000 16.760  0 428  VAL A CG2   1 ? 
ATOM   3264 N N     A SER A 1 430 ? -16.786 15.582  -18.686 0.500 20.249  0 429  SER A N     1 ? 
ATOM   3265 N N     B SER A 1 430 ? -16.787 15.573  -18.698 0.500 20.998  0 429  SER A N     1 ? 
ATOM   3266 C CA    A SER A 1 430 ? -18.103 15.434  -19.305 0.500 20.866  0 429  SER A CA    1 ? 
ATOM   3267 C CA    B SER A 1 430 ? -18.072 15.425  -19.372 0.500 22.181  0 429  SER A CA    1 ? 
ATOM   3268 C C     A SER A 1 430 ? -18.762 16.800  -19.423 0.500 21.104  0 429  SER A C     1 ? 
ATOM   3269 C C     B SER A 1 430 ? -18.754 16.785  -19.431 0.500 21.850  0 429  SER A C     1 ? 
ATOM   3270 O O     A SER A 1 430 ? -19.761 17.060  -18.749 0.500 20.084  0 429  SER A O     1 ? 
ATOM   3271 O O     B SER A 1 430 ? -19.734 17.021  -18.722 0.500 20.889  0 429  SER A O     1 ? 
ATOM   3272 C CB    A SER A 1 430 ? -19.013 14.490  -18.525 0.500 20.870  0 429  SER A CB    1 ? 
ATOM   3273 C CB    B SER A 1 430 ? -18.939 14.356  -18.724 0.500 23.308  0 429  SER A CB    1 ? 
ATOM   3274 O OG    A SER A 1 430 ? -19.389 15.079  -17.290 0.500 20.033  0 429  SER A OG    1 ? 
ATOM   3275 O OG    B SER A 1 430 ? -18.375 13.075  -18.986 0.500 24.037  0 429  SER A OG    1 ? 
ATOM   3276 N N     . PRO A 1 431 ? -18.221 17.727  -20.252 1.000 21.691  0 430  PRO A N     1 ? 
ATOM   3277 C CA    . PRO A 1 431 ? -18.781 19.074  -20.331 1.000 20.573  0 430  PRO A CA    1 ? 
ATOM   3278 C C     . PRO A 1 431 ? -20.096 19.097  -21.100 1.000 22.394  0 430  PRO A C     1 ? 
ATOM   3279 O O     . PRO A 1 431 ? -20.268 18.339  -22.050 1.000 21.271  0 430  PRO A O     1 ? 
ATOM   3280 C CB    . PRO A 1 431 ? -17.692 19.841  -21.070 1.000 22.391  0 430  PRO A CB    1 ? 
ATOM   3281 C CG    . PRO A 1 431 ? -17.118 18.782  -21.994 1.000 23.797  0 430  PRO A CG    1 ? 
ATOM   3282 C CD    . PRO A 1 431 ? -17.039 17.554  -21.112 1.000 21.335  0 430  PRO A CD    1 ? 
ATOM   3283 N N     . ALA A 1 432 ? -20.936 20.069  -20.748 1.000 21.348  0 431  ALA A N     1 ? 
ATOM   3284 C CA    . ALA A 1 432 ? -22.189 20.310  -21.424 1.000 23.248  0 431  ALA A CA    1 ? 
ATOM   3285 C C     . ALA A 1 432 ? -22.013 21.420  -22.459 1.000 24.148  0 431  ALA A C     1 ? 
ATOM   3286 O O     . ALA A 1 432 ? -22.843 21.528  -23.342 1.000 24.603  0 431  ALA A O     1 ? 
ATOM   3287 C CB    . ALA A 1 432 ? -23.221 20.680  -20.401 1.000 22.940  0 431  ALA A CB    1 ? 
ATOM   3288 N N     . SER A 1 433 ? -20.963 22.260  -22.344 1.000 20.223  0 432  SER A N     1 ? 
ATOM   3289 C CA    . SER A 1 433 ? -20.784 23.384  -23.252 1.000 19.183  0 432  SER A CA    1 ? 
ATOM   3290 C C     . SER A 1 433 ? -20.479 22.866  -24.658 1.000 17.970  0 432  SER A C     1 ? 
ATOM   3291 O O     . SER A 1 433 ? -19.877 21.822  -24.804 1.000 20.259  0 432  SER A O     1 ? 
ATOM   3292 C CB    . SER A 1 433 ? -19.701 24.338  -22.803 1.000 19.273  0 432  SER A CB    1 ? 
ATOM   3293 O OG    . SER A 1 433 ? -19.881 24.857  -21.480 1.000 19.422  0 432  SER A OG    1 ? 
ATOM   3294 N N     . GLU A 1 434 ? -20.848 23.637  -25.676 1.000 19.168  0 433  GLU A N     1 ? 
ATOM   3295 C CA    . GLU A 1 434 ? -20.661 23.257  -27.070 1.000 22.460  0 433  GLU A CA    1 ? 
ATOM   3296 C C     . GLU A 1 434 ? -20.403 24.540  -27.826 1.000 22.328  0 433  GLU A C     1 ? 
ATOM   3297 O O     . GLU A 1 434 ? -21.029 25.550  -27.506 1.000 22.312  0 433  GLU A O     1 ? 
ATOM   3298 C CB    . GLU A 1 434 ? -21.947 22.673  -27.672 1.000 30.753  0 433  GLU A CB    1 ? 
ATOM   3299 C CG    . GLU A 1 434 ? -21.923 21.180  -27.958 1.000 42.682  0 433  GLU A CG    1 ? 
ATOM   3300 C CD    . GLU A 1 434 ? -23.162 20.681  -28.695 1.000 37.994  0 433  GLU A CD    1 ? 
ATOM   3301 O OE1   . GLU A 1 434 ? -23.554 21.347  -29.652 1.000 37.453  0 433  GLU A OE1   1 ? 
ATOM   3302 O OE2   . GLU A 1 434 ? -23.735 19.641  -28.322 1.000 55.887  0 433  GLU A OE2   1 ? 
ATOM   3303 N N     . GLY A 1 435 ? -19.572 24.482  -28.864 1.000 20.524  0 434  GLY A N     1 ? 
ATOM   3304 C CA    . GLY A 1 435 ? -19.242 25.655  -29.639 1.000 19.952  0 434  GLY A CA    1 ? 
ATOM   3305 C C     . GLY A 1 435 ? -19.119 25.341  -31.125 1.000 19.511  0 434  GLY A C     1 ? 
ATOM   3306 O O     . GLY A 1 435 ? -19.776 24.431  -31.595 1.000 20.823  0 434  GLY A O     1 ? 
ATOM   3307 N N     . THR A 1 436 ? -18.271 26.119  -31.820 1.000 19.591  0 435  THR A N     1 ? 
ATOM   3308 C CA    . THR A 1 436 ? -18.137 26.040  -33.270 1.000 20.702  0 435  THR A CA    1 ? 
ATOM   3309 C C     . THR A 1 436 ? -16.695 26.263  -33.739 1.000 20.442  0 435  THR A C     1 ? 
ATOM   3310 O O     . THR A 1 436 ? -15.918 26.975  -33.116 1.000 20.609  0 435  THR A O     1 ? 
ATOM   3311 C CB    . THR A 1 436 ? -19.064 27.062  -33.932 1.000 21.878  0 435  THR A CB    1 ? 
ATOM   3312 O OG1   . THR A 1 436 ? -18.646 28.348  -33.486 1.000 23.932  0 435  THR A OG1   1 ? 
ATOM   3313 C CG2   . THR A 1 436 ? -20.524 26.840  -33.590 1.000 24.896  0 435  THR A CG2   1 ? 
ATOM   3314 N N     . VAL A 1 437 ? -16.426 25.726  -34.950 1.000 18.985  0 436  VAL A N     1 ? 
ATOM   3315 C CA    . VAL A 1 437 ? -15.318 26.061  -35.810 1.000 19.664  0 436  VAL A CA    1 ? 
ATOM   3316 C C     . VAL A 1 437 ? -15.914 26.624  -37.102 1.000 20.833  0 436  VAL A C     1 ? 
ATOM   3317 O O     . VAL A 1 437 ? -16.755 25.969  -37.713 1.000 20.442  0 436  VAL A O     1 ? 
ATOM   3318 C CB    . VAL A 1 437 ? -14.439 24.831  -36.143 1.000 22.290  0 436  VAL A CB    1 ? 
ATOM   3319 C CG1   . VAL A 1 437 ? -13.321 25.228  -37.098 1.000 24.914  0 436  VAL A CG1   1 ? 
ATOM   3320 C CG2   . VAL A 1 437 ? -13.886 24.167  -34.886 1.000 24.489  0 436  VAL A CG2   1 ? 
ATOM   3321 N N     . ARG A 1 438 ? -15.536 27.865  -37.438 1.000 20.702  0 437  ARG A N     1 ? 
ATOM   3322 C CA    . ARG A 1 438 ? -16.055 28.568  -38.610 1.000 21.736  0 437  ARG A CA    1 ? 
ATOM   3323 C C     . ARG A 1 438 ? -14.905 29.128  -39.427 1.000 21.972  0 437  ARG A C     1 ? 
ATOM   3324 O O     . ARG A 1 438 ? -13.759 29.189  -38.965 1.000 21.875  0 437  ARG A O     1 ? 
ATOM   3325 C CB    . ARG A 1 438 ? -16.979 29.703  -38.164 1.000 25.579  0 437  ARG A CB    1 ? 
ATOM   3326 C CG    . ARG A 1 438 ? -18.318 29.309  -37.568 1.000 29.663  0 437  ARG A CG    1 ? 
ATOM   3327 C CD    . ARG A 1 438 ? -19.143 30.545  -37.268 1.000 33.675  0 437  ARG A CD    1 ? 
ATOM   3328 N NE    . ARG A 1 438 ? -20.528 30.111  -37.036 1.000 36.628  0 437  ARG A NE    1 ? 
ATOM   3329 C CZ    . ARG A 1 438 ? -21.157 30.112  -35.859 1.000 39.117  0 437  ARG A CZ    1 ? 
ATOM   3330 N NH1   . ARG A 1 438 ? -20.555 30.560  -34.770 1.000 38.723  0 437  ARG A NH1   1 ? 
ATOM   3331 N NH2   . ARG A 1 438 ? -22.408 29.684  -35.779 1.000 42.251  0 437  ARG A NH2   1 ? 
ATOM   3332 N N     . LEU A 1 439 ? -15.180 29.413  -40.713 1.000 23.437  0 438  LEU A N     1 ? 
ATOM   3333 C CA    . LEU A 1 439 ? -14.223 30.085  -41.564 1.000 23.299  0 438  LEU A CA    1 ? 
ATOM   3334 C C     . LEU A 1 439 ? -14.229 31.582  -41.268 1.000 23.931  0 438  LEU A C     1 ? 
ATOM   3335 O O     . LEU A 1 439 ? -15.277 32.169  -40.984 1.000 22.562  0 438  LEU A O     1 ? 
ATOM   3336 C CB    . LEU A 1 439 ? -14.581 29.886  -43.035 1.000 24.179  0 438  LEU A CB    1 ? 
ATOM   3337 C CG    . LEU A 1 439 ? -14.622 28.451  -43.552 1.000 26.160  0 438  LEU A CG    1 ? 
ATOM   3338 C CD1   . LEU A 1 439 ? -14.975 28.458  -45.048 1.000 28.244  0 438  LEU A CD1   1 ? 
ATOM   3339 C CD2   . LEU A 1 439 ? -13.277 27.784  -43.309 1.000 25.871  0 438  LEU A CD2   1 ? 
ATOM   3340 N N     . ASN A 1 440 ? -13.058 32.191  -41.409 1.000 22.136  0 439  ASN A N     1 ? 
ATOM   3341 C CA    . ASN A 1 440 ? -12.929 33.635  -41.407 1.000 25.170  0 439  ASN A CA    1 ? 
ATOM   3342 C C     . ASN A 1 440 ? -12.983 34.132  -42.848 1.000 27.827  0 439  ASN A C     1 ? 
ATOM   3343 O O     . ASN A 1 440 ? -13.326 35.288  -43.105 1.000 29.704  0 439  ASN A O     1 ? 
ATOM   3344 C CB    . ASN A 1 440 ? -11.606 34.088  -40.812 1.000 26.963  0 439  ASN A CB    1 ? 
ATOM   3345 C CG    . ASN A 1 440 ? -11.647 34.259  -39.311 1.000 33.649  0 439  ASN A CG    1 ? 
ATOM   3346 O OD1   . ASN A 1 440 ? -12.503 34.994  -38.803 1.000 37.234  0 439  ASN A OD1   1 ? 
ATOM   3347 N ND2   . ASN A 1 440 ? -10.724 33.628  -38.588 1.000 35.523  0 439  ASN A ND2   1 ? 
ATOM   3348 N N     . SER A 1 441 ? -12.610 33.254  -43.784 1.000 24.231  0 440  SER A N     1 ? 
ATOM   3349 C CA    . SER A 1 441 ? -12.207 33.660  -45.121 1.000 26.405  0 440  SER A CA    1 ? 
ATOM   3350 C C     . SER A 1 441 ? -12.296 32.457  -46.054 1.000 26.091  0 440  SER A C     1 ? 
ATOM   3351 O O     . SER A 1 441 ? -12.284 31.336  -45.564 1.000 24.485  0 440  SER A O     1 ? 
ATOM   3352 C CB    . SER A 1 441 ? -10.793 34.194  -45.038 1.000 28.163  0 440  SER A CB    1 ? 
ATOM   3353 O OG    . SER A 1 441 ? -10.209 34.506  -46.284 1.000 34.374  0 440  SER A OG    1 ? 
ATOM   3354 N N     . THR A 1 442 ? -12.283 32.695  -47.383 1.000 25.869  0 441  THR A N     1 ? 
ATOM   3355 C CA    . THR A 1 442 ? -12.183 31.615  -48.353 1.000 26.617  0 441  THR A CA    1 ? 
ATOM   3356 C C     . THR A 1 442 ? -10.721 31.274  -48.596 1.000 29.597  0 441  THR A C     1 ? 
ATOM   3357 O O     . THR A 1 442 ? -10.433 30.319  -49.324 1.000 30.103  0 441  THR A O     1 ? 
ATOM   3358 C CB    . THR A 1 442 ? -12.870 31.953  -49.680 1.000 28.298  0 441  THR A CB    1 ? 
ATOM   3359 O OG1   . THR A 1 442 ? -12.319 33.204  -50.049 1.000 29.582  0 441  THR A OG1   1 ? 
ATOM   3360 C CG2   . THR A 1 442 ? -14.366 32.164  -49.543 1.000 30.908  0 441  THR A CG2   1 ? 
ATOM   3361 N N     . ASN A 1 443 ? -9.799  32.072  -48.044 1.000 26.315  0 442  ASN A N     1 ? 
ATOM   3362 C CA    . ASN A 1 443 ? -8.393  31.737  -48.130 1.000 25.029  0 442  ASN A CA    1 ? 
ATOM   3363 C C     . ASN A 1 443 ? -8.134  30.469  -47.323 1.000 27.434  0 442  ASN A C     1 ? 
ATOM   3364 O O     . ASN A 1 443 ? -8.211  30.457  -46.082 1.000 24.958  0 442  ASN A O     1 ? 
ATOM   3365 C CB    . ASN A 1 443 ? -7.528  32.873  -47.621 1.000 26.497  0 442  ASN A CB    1 ? 
ATOM   3366 C CG    . ASN A 1 443 ? -6.050  32.565  -47.569 1.000 25.894  0 442  ASN A CG    1 ? 
ATOM   3367 O OD1   . ASN A 1 443 ? -5.559  31.554  -48.077 1.000 26.821  0 442  ASN A OD1   1 ? 
ATOM   3368 N ND2   . ASN A 1 443 ? -5.314  33.408  -46.869 1.000 29.208  0 442  ASN A ND2   1 ? 
ATOM   3369 N N     . PRO A 1 444 ? -7.699  29.378  -47.984 1.000 28.161  0 443  PRO A N     1 ? 
ATOM   3370 C CA    . PRO A 1 444 ? -7.458  28.142  -47.256 1.000 26.660  0 443  PRO A CA    1 ? 
ATOM   3371 C C     . PRO A 1 444 ? -6.344  28.239  -46.216 1.000 26.318  0 443  PRO A C     1 ? 
ATOM   3372 O O     . PRO A 1 444 ? -6.289  27.407  -45.316 1.000 27.922  0 443  PRO A O     1 ? 
ATOM   3373 C CB    . PRO A 1 444 ? -7.157  27.106  -48.376 1.000 27.617  0 443  PRO A CB    1 ? 
ATOM   3374 C CG    . PRO A 1 444 ? -6.786  27.891  -49.590 1.000 28.918  0 443  PRO A CG    1 ? 
ATOM   3375 C CD    . PRO A 1 444 ? -7.339  29.298  -49.420 1.000 30.913  0 443  PRO A CD    1 ? 
ATOM   3376 N N     . PHE A 1 445 ? -5.431  29.226  -46.323 1.000 24.345  0 444  PHE A N     1 ? 
ATOM   3377 C CA    . PHE A 1 445 ? -4.335  29.348  -45.364 1.000 23.186  0 444  PHE A CA    1 ? 
ATOM   3378 C C     . PHE A 1 445 ? -4.683  30.325  -44.235 1.000 24.082  0 444  PHE A C     1 ? 
ATOM   3379 O O     . PHE A 1 445 ? -3.835  30.623  -43.405 1.000 24.833  0 444  PHE A O     1 ? 
ATOM   3380 C CB    . PHE A 1 445 ? -3.056  29.765  -46.096 1.000 22.342  0 444  PHE A CB    1 ? 
ATOM   3381 C CG    . PHE A 1 445 ? -2.539  28.601  -46.935 1.000 24.118  0 444  PHE A CG    1 ? 
ATOM   3382 C CD1   . PHE A 1 445 ? -1.728  27.629  -46.367 1.000 24.796  0 444  PHE A CD1   1 ? 
ATOM   3383 C CD2   . PHE A 1 445 ? -2.903  28.462  -48.264 1.000 23.951  0 444  PHE A CD2   1 ? 
ATOM   3384 C CE1   . PHE A 1 445 ? -1.297  26.542  -47.114 1.000 26.050  0 444  PHE A CE1   1 ? 
ATOM   3385 C CE2   . PHE A 1 445 ? -2.453  27.385  -49.010 1.000 22.691  0 444  PHE A CE2   1 ? 
ATOM   3386 C CZ    . PHE A 1 445 ? -1.644  26.428  -48.429 1.000 23.246  0 444  PHE A CZ    1 ? 
ATOM   3387 N N     . GLU A 1 446 ? -5.915  30.837  -44.202 1.000 24.218  0 445  GLU A N     1 ? 
ATOM   3388 C CA    . GLU A 1 446 ? -6.308  31.748  -43.143 1.000 24.972  0 445  GLU A CA    1 ? 
ATOM   3389 C C     . GLU A 1 446 ? -6.682  30.890  -41.946 1.000 25.725  0 445  GLU A C     1 ? 
ATOM   3390 O O     . GLU A 1 446 ? -7.220  29.798  -42.117 1.000 26.484  0 445  GLU A O     1 ? 
ATOM   3391 C CB    . GLU A 1 446 ? -7.482  32.661  -43.508 1.000 27.597  0 445  GLU A CB    1 ? 
ATOM   3392 C CG    . GLU A 1 446 ? -7.756  33.802  -42.518 1.000 29.234  0 445  GLU A CG    1 ? 
ATOM   3393 C CD    . GLU A 1 446 ? -6.554  34.705  -42.232 1.000 34.289  0 445  GLU A CD    1 ? 
ATOM   3394 O OE1   . GLU A 1 446 ? -6.374  35.773  -42.892 1.000 33.835  0 445  GLU A OE1   1 ? 
ATOM   3395 O OE2   . GLU A 1 446 ? -5.773  34.326  -41.323 1.000 34.054  0 445  GLU A OE2   1 ? 
ATOM   3396 N N     . PHE A 1 447 ? -6.399  31.430  -40.758 1.000 29.003  0 446  PHE A N     1 ? 
ATOM   3397 C CA    . PHE A 1 447 ? -6.757  30.797  -39.506 1.000 27.921  0 446  PHE A CA    1 ? 
ATOM   3398 C C     . PHE A 1 447 ? -8.271  30.620  -39.459 1.000 25.005  0 446  PHE A C     1 ? 
ATOM   3399 O O     . PHE A 1 447 ? -9.025  31.485  -39.887 1.000 23.651  0 446  PHE A O     1 ? 
ATOM   3400 C CB    . PHE A 1 447 ? -6.299  31.644  -38.310 1.000 30.368  0 446  PHE A CB    1 ? 
ATOM   3401 C CG    . PHE A 1 447 ? -4.813  32.015  -38.348 1.000 37.653  0 446  PHE A CG    1 ? 
ATOM   3402 C CD1   . PHE A 1 447 ? -3.838  31.033  -38.270 1.000 42.805  0 446  PHE A CD1   1 ? 
ATOM   3403 C CD2   . PHE A 1 447 ? -4.405  33.346  -38.449 1.000 45.039  0 446  PHE A CD2   1 ? 
ATOM   3404 C CE1   . PHE A 1 447 ? -2.486  31.364  -38.317 1.000 49.097  0 446  PHE A CE1   1 ? 
ATOM   3405 C CE2   . PHE A 1 447 ? -3.055  33.681  -38.482 1.000 49.521  0 446  PHE A CE2   1 ? 
ATOM   3406 C CZ    . PHE A 1 447 ? -2.099  32.687  -38.413 1.000 50.288  0 446  PHE A CZ    1 ? 
ATOM   3407 N N     . PRO A 1 448 ? -8.769  29.514  -38.886 1.000 23.511  0 447  PRO A N     1 ? 
ATOM   3408 C CA    . PRO A 1 448 ? -10.205 29.379  -38.626 1.000 24.567  0 447  PRO A CA    1 ? 
ATOM   3409 C C     . PRO A 1 448 ? -10.635 30.175  -37.409 1.000 24.928  0 447  PRO A C     1 ? 
ATOM   3410 O O     . PRO A 1 448 ? -9.817  30.615  -36.607 1.000 27.276  0 447  PRO A O     1 ? 
ATOM   3411 C CB    . PRO A 1 448 ? -10.385 27.892  -38.414 1.000 26.794  0 447  PRO A CB    1 ? 
ATOM   3412 C CG    . PRO A 1 448 ? -9.057  27.497  -37.778 1.000 29.946  0 447  PRO A CG    1 ? 
ATOM   3413 C CD    . PRO A 1 448 ? -7.986  28.350  -38.457 1.000 29.335  0 447  PRO A CD    1 ? 
ATOM   3414 N N     . LEU A 1 449 ? -11.950 30.335  -37.249 1.000 21.867  0 448  LEU A N     1 ? 
ATOM   3415 C CA    . LEU A 1 449 ? -12.483 30.981  -36.056 1.000 23.598  0 448  LEU A CA    1 ? 
ATOM   3416 C C     . LEU A 1 449 ? -12.913 29.904  -35.058 1.000 24.708  0 448  LEU A C     1 ? 
ATOM   3417 O O     . LEU A 1 449 ? -13.774 29.065  -35.364 1.000 25.973  0 448  LEU A O     1 ? 
ATOM   3418 C CB    . LEU A 1 449 ? -13.626 31.792  -36.651 1.000 25.955  0 448  LEU A CB    1 ? 
ATOM   3419 C CG    . LEU A 1 449 ? -14.201 32.916  -35.811 1.000 35.524  0 448  LEU A CG    1 ? 
ATOM   3420 C CD1   . LEU A 1 449 ? -13.128 33.961  -35.486 1.000 35.453  0 448  LEU A CD1   1 ? 
ATOM   3421 C CD2   . LEU A 1 449 ? -15.375 33.476  -36.627 1.000 33.610  0 448  LEU A CD2   1 ? 
ATOM   3422 N N     . LEU A 1 450 ? -12.278 29.893  -33.870 1.000 21.478  0 449  LEU A N     1 ? 
ATOM   3423 C CA    . LEU A 1 450 ? -12.434 28.812  -32.916 1.000 21.886  0 449  LEU A CA    1 ? 
ATOM   3424 C C     . LEU A 1 450 ? -13.188 29.338  -31.713 1.000 23.159  0 449  LEU A C     1 ? 
ATOM   3425 O O     . LEU A 1 450 ? -12.705 30.283  -31.080 1.000 22.857  0 449  LEU A O     1 ? 
ATOM   3426 C CB    . LEU A 1 450 ? -11.050 28.336  -32.463 1.000 23.638  0 449  LEU A CB    1 ? 
ATOM   3427 C CG    . LEU A 1 450 ? -10.100 27.854  -33.558 1.000 26.276  0 449  LEU A CG    1 ? 
ATOM   3428 C CD1   . LEU A 1 450 ? -8.769  27.538  -32.946 1.000 30.272  0 449  LEU A CD1   1 ? 
ATOM   3429 C CD2   . LEU A 1 450 ? -10.671 26.643  -34.254 1.000 26.442  0 449  LEU A CD2   1 ? 
ATOM   3430 N N     . ASP A 1 451 ? -14.345 28.738  -31.411 1.000 23.776  0 450  ASP A N     1 ? 
ATOM   3431 C CA    . ASP A 1 451 ? -15.138 29.198  -30.289 1.000 24.909  0 450  ASP A CA    1 ? 
ATOM   3432 C C     . ASP A 1 451 ? -15.680 28.001  -29.524 1.000 23.675  0 450  ASP A C     1 ? 
ATOM   3433 O O     . ASP A 1 451 ? -16.835 27.622  -29.729 1.000 24.205  0 450  ASP A O     1 ? 
ATOM   3434 C CB    . ASP A 1 451 ? -16.296 30.104  -30.696 1.000 25.250  0 450  ASP A CB    1 ? 
ATOM   3435 C CG    . ASP A 1 451 ? -17.066 30.655  -29.501 1.000 30.343  0 450  ASP A CG    1 ? 
ATOM   3436 O OD1   . ASP A 1 451 ? -16.556 30.529  -28.342 1.000 27.486  0 450  ASP A OD1   1 ? 
ATOM   3437 O OD2   . ASP A 1 451 ? -18.191 31.157  -29.703 1.000 27.223  0 450  ASP A OD2   1 ? 
ATOM   3438 N N     . PRO A 1 452 ? -14.888 27.386  -28.610 1.000 22.180  0 451  PRO A N     1 ? 
ATOM   3439 C CA    . PRO A 1 452 ? -15.378 26.258  -27.820 1.000 22.583  0 451  PRO A CA    1 ? 
ATOM   3440 C C     . PRO A 1 452 ? -16.484 26.564  -26.800 1.000 21.880  0 451  PRO A C     1 ? 
ATOM   3441 O O     . PRO A 1 452 ? -17.105 25.650  -26.272 1.000 22.442  0 451  PRO A O     1 ? 
ATOM   3442 C CB    . PRO A 1 452 ? -14.085 25.731  -27.162 1.000 24.650  0 451  PRO A CB    1 ? 
ATOM   3443 C CG    . PRO A 1 452 ? -13.175 26.921  -27.095 1.000 24.981  0 451  PRO A CG    1 ? 
ATOM   3444 C CD    . PRO A 1 452 ? -13.465 27.708  -28.339 1.000 22.841  0 451  PRO A CD    1 ? 
ATOM   3445 N N     . GLN A 1 453 ? -16.707 27.847  -26.520 1.000 23.380  0 452  GLN A N     1 ? 
ATOM   3446 C CA    . GLN A 1 453 ? -17.625 28.286  -25.474 1.000 25.538  0 452  GLN A CA    1 ? 
ATOM   3447 C C     . GLN A 1 453 ? -17.260 27.652  -24.129 1.000 22.086  0 452  GLN A C     1 ? 
ATOM   3448 O O     . GLN A 1 453 ? -18.105 27.167  -23.376 1.000 21.128  0 452  GLN A O     1 ? 
ATOM   3449 C CB    . GLN A 1 453 ? -19.070 28.076  -25.939 1.000 24.807  0 452  GLN A CB    1 ? 
ATOM   3450 C CG    . GLN A 1 453 ? -19.424 28.943  -27.135 1.000 26.721  0 452  GLN A CG    1 ? 
ATOM   3451 C CD    . GLN A 1 453 ? -20.878 28.856  -27.557 1.000 32.320  0 452  GLN A CD    1 ? 
ATOM   3452 O OE1   . GLN A 1 453 ? -21.211 29.048  -28.736 1.000 40.286  0 452  GLN A OE1   1 ? 
ATOM   3453 N NE2   . GLN A 1 453 ? -21.751 28.501  -26.625 1.000 31.572  0 452  GLN A NE2   1 ? 
ATOM   3454 N N     . LEU A 1 454 ? -15.973 27.690  -23.788 1.000 20.776  0 453  LEU A N     1 ? 
ATOM   3455 C CA    . LEU A 1 454 ? -15.507 27.045  -22.573 1.000 21.121  0 453  LEU A CA    1 ? 
ATOM   3456 C C     . LEU A 1 454 ? -16.182 27.625  -21.326 1.000 21.083  0 453  LEU A C     1 ? 
ATOM   3457 O O     . LEU A 1 454 ? -16.300 28.840  -21.200 1.000 21.573  0 453  LEU A O     1 ? 
ATOM   3458 C CB    . LEU A 1 454 ? -14.002 27.215  -22.433 1.000 24.418  0 453  LEU A CB    1 ? 
ATOM   3459 C CG    . LEU A 1 454 ? -13.139 26.395  -23.380 1.000 28.519  0 453  LEU A CG    1 ? 
ATOM   3460 C CD1   . LEU A 1 454 ? -11.743 27.022  -23.344 1.000 31.647  0 453  LEU A CD1   1 ? 
ATOM   3461 C CD2   . LEU A 1 454 ? -13.193 24.909  -23.025 1.000 27.774  0 453  LEU A CD2   1 ? 
ATOM   3462 N N     . LEU A 1 455 ? -16.623 26.733  -20.436 1.000 19.145  0 454  LEU A N     1 ? 
ATOM   3463 C CA    . LEU A 1 455 ? -17.309 27.051  -19.190 1.000 22.403  0 454  LEU A CA    1 ? 
ATOM   3464 C C     . LEU A 1 455 ? -18.570 27.888  -19.409 1.000 23.424  0 454  LEU A C     1 ? 
ATOM   3465 O O     . LEU A 1 455 ? -19.051 28.509  -18.455 1.000 22.159  0 454  LEU A O     1 ? 
ATOM   3466 C CB    . LEU A 1 455 ? -16.417 27.771  -18.182 1.000 22.057  0 454  LEU A CB    1 ? 
ATOM   3467 C CG    . LEU A 1 455 ? -15.417 26.962  -17.370 1.000 24.362  0 454  LEU A CG    1 ? 
ATOM   3468 C CD1   . LEU A 1 455 ? -15.245 27.791  -16.081 1.000 24.222  0 454  LEU A CD1   1 ? 
ATOM   3469 C CD2   . LEU A 1 455 ? -15.665 25.507  -17.046 1.000 21.708  0 454  LEU A CD2   1 ? 
ATOM   3470 N N     . SER A 1 456 ? -19.169 27.852  -20.611 1.000 22.368  0 455  SER A N     1 ? 
ATOM   3471 C CA    . SER A 1 456 ? -20.400 28.610  -20.816 1.000 24.624  0 455  SER A CA    1 ? 
ATOM   3472 C C     . SER A 1 456 ? -21.570 27.954  -20.093 1.000 23.659  0 455  SER A C     1 ? 
ATOM   3473 O O     . SER A 1 456 ? -22.435 28.632  -19.565 1.000 23.976  0 455  SER A O     1 ? 
ATOM   3474 C CB    . SER A 1 456 ? -20.711 28.857  -22.290 1.000 26.752  0 455  SER A CB    1 ? 
ATOM   3475 O OG    . SER A 1 456 ? -20.809 27.620  -22.976 1.000 33.113  0 455  SER A OG    1 ? 
ATOM   3476 N N     . SER A 1 457 ? -21.584 26.630  -20.011 1.000 21.109  0 456  SER A N     1 ? 
ATOM   3477 C CA    . SER A 1 457 ? -22.645 25.928  -19.327 1.000 23.251  0 456  SER A CA    1 ? 
ATOM   3478 C C     . SER A 1 457 ? -22.457 26.069  -17.821 1.000 24.436  0 456  SER A C     1 ? 
ATOM   3479 O O     . SER A 1 457 ? -21.340 25.913  -17.315 1.000 21.349  0 456  SER A O     1 ? 
ATOM   3480 C CB    . SER A 1 457 ? -22.729 24.464  -19.732 1.000 22.573  0 456  SER A CB    1 ? 
ATOM   3481 O OG    . SER A 1 457 ? -23.709 23.826  -18.926 1.000 21.973  0 456  SER A OG    1 ? 
ATOM   3482 N N     . GLU A 1 458 ? -23.569 26.350  -17.119 1.000 23.232  0 457  GLU A N     1 ? 
ATOM   3483 C CA    . GLU A 1 458 ? -23.559 26.333  -15.658 1.000 26.816  0 457  GLU A CA    1 ? 
ATOM   3484 C C     . GLU A 1 458 ? -23.147 24.963  -15.113 1.000 22.794  0 457  GLU A C     1 ? 
ATOM   3485 O O     . GLU A 1 458 ? -22.588 24.881  -14.020 1.000 20.558  0 457  GLU A O     1 ? 
ATOM   3486 C CB    . GLU A 1 458 ? -24.875 26.883  -15.102 1.000 32.645  0 457  GLU A CB    1 ? 
ATOM   3487 C CG    . GLU A 1 458 ? -24.995 28.384  -15.371 1.000 40.275  0 457  GLU A CG    1 ? 
ATOM   3488 C CD    . GLU A 1 458 ? -26.124 29.071  -14.610 1.000 52.239  0 457  GLU A CD    1 ? 
ATOM   3489 O OE1   . GLU A 1 458 ? -27.026 28.341  -14.134 1.000 53.511  0 457  GLU A OE1   1 ? 
ATOM   3490 O OE2   . GLU A 1 458 ? -26.088 30.321  -14.472 1.000 56.141  0 457  GLU A OE2   1 ? 
ATOM   3491 N N     . PHE A 1 459 ? -23.402 23.886  -15.866 1.000 20.831  0 458  PHE A N     1 ? 
ATOM   3492 C CA    . PHE A 1 459 ? -23.019 22.551  -15.439 1.000 18.935  0 458  PHE A CA    1 ? 
ATOM   3493 C C     . PHE A 1 459 ? -21.491 22.527  -15.315 1.000 18.958  0 458  PHE A C     1 ? 
ATOM   3494 O O     . PHE A 1 459 ? -20.963 22.048  -14.321 1.000 21.188  0 458  PHE A O     1 ? 
ATOM   3495 C CB    . PHE A 1 459 ? -23.560 21.480  -16.403 1.000 20.706  0 458  PHE A CB    1 ? 
ATOM   3496 C CG    . PHE A 1 459 ? -23.079 20.095  -16.022 1.000 19.330  0 458  PHE A CG    1 ? 
ATOM   3497 C CD1   . PHE A 1 459 ? -21.813 19.649  -16.403 1.000 20.217  0 458  PHE A CD1   1 ? 
ATOM   3498 C CD2   . PHE A 1 459 ? -23.797 19.327  -15.112 1.000 21.186  0 458  PHE A CD2   1 ? 
ATOM   3499 C CE1   . PHE A 1 459 ? -21.320 18.435  -15.953 1.000 22.473  0 458  PHE A CE1   1 ? 
ATOM   3500 C CE2   . PHE A 1 459 ? -23.326 18.091  -14.713 1.000 21.964  0 458  PHE A CE2   1 ? 
ATOM   3501 C CZ    . PHE A 1 459 ? -22.095 17.639  -15.142 1.000 22.469  0 458  PHE A CZ    1 ? 
ATOM   3502 N N     . ASP A 1 460 ? -20.799 23.115  -16.296 1.000 17.850  0 459  ASP A N     1 ? 
ATOM   3503 C CA    . ASP A 1 460 ? -19.340 23.041  -16.360 1.000 17.977  0 459  ASP A CA    1 ? 
ATOM   3504 C C     . ASP A 1 460 ? -18.735 23.941  -15.282 1.000 19.566  0 459  ASP A C     1 ? 
ATOM   3505 O O     . ASP A 1 460 ? -17.750 23.582  -14.679 1.000 19.421  0 459  ASP A O     1 ? 
ATOM   3506 C CB    . ASP A 1 460 ? -18.842 23.427  -17.747 1.000 19.009  0 459  ASP A CB    1 ? 
ATOM   3507 C CG    . ASP A 1 460 ? -19.291 22.491  -18.866 1.000 19.501  0 459  ASP A CG    1 ? 
ATOM   3508 O OD1   . ASP A 1 460 ? -19.882 21.452  -18.527 1.000 22.177  0 459  ASP A OD1   1 ? 
ATOM   3509 O OD2   . ASP A 1 460 ? -19.062 22.816  -20.070 1.000 20.384  0 459  ASP A OD2   1 ? 
ATOM   3510 N N     . GLN A 1 461 ? -19.347 25.104  -15.045 1.000 19.242  0 460  GLN A N     1 ? 
ATOM   3511 C CA    . GLN A 1 461 ? -18.900 26.014  -14.003 1.000 20.609  0 460  GLN A CA    1 ? 
ATOM   3512 C C     . GLN A 1 461 ? -18.990 25.336  -12.643 1.000 21.558  0 460  GLN A C     1 ? 
ATOM   3513 O O     . GLN A 1 461 ? -18.044 25.346  -11.877 1.000 21.035  0 460  GLN A O     1 ? 
ATOM   3514 C CB    . GLN A 1 461 ? -19.763 27.276  -14.040 1.000 21.115  0 460  GLN A CB    1 ? 
ATOM   3515 C CG    . GLN A 1 461 ? -19.515 28.120  -15.286 1.000 22.712  0 460  GLN A CG    1 ? 
ATOM   3516 C CD    . GLN A 1 461 ? -20.475 29.290  -15.389 1.000 28.308  0 460  GLN A CD    1 ? 
ATOM   3517 O OE1   . GLN A 1 461 ? -21.037 29.717  -14.386 1.000 24.924  0 460  GLN A OE1   1 ? 
ATOM   3518 N NE2   . GLN A 1 461 ? -20.690 29.818  -16.586 1.000 27.006  0 460  GLN A NE2   1 ? 
ATOM   3519 N N     . HIS A 1 462 ? -20.157 24.760  -12.341 1.000 21.600  0 461  HIS A N     1 ? 
ATOM   3520 C CA    . HIS A 1 462 ? -20.373 24.080  -11.080 1.000 23.719  0 461  HIS A CA    1 ? 
ATOM   3521 C C     . HIS A 1 462 ? -19.348 22.955  -10.906 1.000 21.490  0 461  HIS A C     1 ? 
ATOM   3522 O O     . HIS A 1 462 ? -18.803 22.764  -9.826  1.000 22.028  0 461  HIS A O     1 ? 
ATOM   3523 C CB    . HIS A 1 462 ? -21.812 23.565  -11.022 1.000 26.964  0 461  HIS A CB    1 ? 
ATOM   3524 C CG    . HIS A 1 462 ? -22.109 22.718  -9.821  1.000 33.549  0 461  HIS A CG    1 ? 
ATOM   3525 N ND1   . HIS A 1 462 ? -22.076 21.335  -9.833  1.000 38.473  0 461  HIS A ND1   1 ? 
ATOM   3526 C CD2   . HIS A 1 462 ? -22.435 23.067  -8.562  1.000 35.248  0 461  HIS A CD2   1 ? 
ATOM   3527 C CE1   . HIS A 1 462 ? -22.383 20.874  -8.613  1.000 38.079  0 461  HIS A CE1   1 ? 
ATOM   3528 N NE2   . HIS A 1 462 ? -22.593 21.909  -7.819  1.000 35.775  0 461  HIS A NE2   1 ? 
ATOM   3529 N N     . THR A 1 463 ? -19.135 22.169  -11.962 1.000 19.501  0 462  THR A N     1 ? 
ATOM   3530 C CA    . THR A 1 463 ? -18.374 20.948  -11.862 1.000 18.924  0 462  THR A CA    1 ? 
ATOM   3531 C C     . THR A 1 463 ? -16.894 21.276  -11.702 1.000 19.196  0 462  THR A C     1 ? 
ATOM   3532 O O     . THR A 1 463 ? -16.223 20.574  -10.961 1.000 19.232  0 462  THR A O     1 ? 
ATOM   3533 C CB    . THR A 1 463 ? -18.667 20.040  -13.067 1.000 20.722  0 462  THR A CB    1 ? 
ATOM   3534 O OG1   . THR A 1 463 ? -20.066 19.722  -13.038 1.000 21.600  0 462  THR A OG1   1 ? 
ATOM   3535 C CG2   . THR A 1 463 ? -17.868 18.748  -13.053 1.000 21.227  0 462  THR A CG2   1 ? 
ATOM   3536 N N     . ILE A 1 464 ? -16.391 22.343  -12.354 1.000 18.462  0 463  ILE A N     1 ? 
ATOM   3537 C CA    . ILE A 1 464 ? -14.958 22.589  -12.264 1.000 18.484  0 463  ILE A CA    1 ? 
ATOM   3538 C C     . ILE A 1 464 ? -14.642 23.158  -10.875 1.000 19.238  0 463  ILE A C     1 ? 
ATOM   3539 O O     . ILE A 1 464 ? -13.610 22.801  -10.287 1.000 19.216  0 463  ILE A O     1 ? 
ATOM   3540 C CB    . ILE A 1 464 ? -14.418 23.426  -13.438 1.000 19.204  0 463  ILE A CB    1 ? 
ATOM   3541 C CG1   . ILE A 1 464 ? -12.912 23.102  -13.698 1.000 19.192  0 463  ILE A CG1   1 ? 
ATOM   3542 C CG2   . ILE A 1 464 ? -14.695 24.926  -13.258 1.000 21.542  0 463  ILE A CG2   1 ? 
ATOM   3543 C CD1   . ILE A 1 464 ? -12.310 23.774  -14.921 1.000 19.563  0 463  ILE A CD1   1 ? 
ATOM   3544 N N     . ILE A 1 465 ? -15.599 23.889  -10.296 1.000 19.070  0 464  ILE A N     1 ? 
ATOM   3545 C CA    . ILE A 1 465 ? -15.397 24.424  -8.951  1.000 20.338  0 464  ILE A CA    1 ? 
ATOM   3546 C C     . ILE A 1 465 ? -15.454 23.275  -7.951  1.000 19.906  0 464  ILE A C     1 ? 
ATOM   3547 O O     . ILE A 1 465 ? -14.640 23.219  -7.039  1.000 21.712  0 464  ILE A O     1 ? 
ATOM   3548 C CB    . ILE A 1 465 ? -16.378 25.558  -8.633  1.000 20.431  0 464  ILE A CB    1 ? 
ATOM   3549 C CG1   . ILE A 1 465 ? -16.046 26.805  -9.463  1.000 22.204  0 464  ILE A CG1   1 ? 
ATOM   3550 C CG2   . ILE A 1 465 ? -16.372 25.880  -7.141  1.000 20.904  0 464  ILE A CG2   1 ? 
ATOM   3551 C CD1   . ILE A 1 465 ? -17.211 27.751  -9.591  1.000 23.541  0 464  ILE A CD1   1 ? 
ATOM   3552 N N     . HIS A 1 466 ? -16.428 22.373  -8.121  1.000 21.771  0 465  HIS A N     1 ? 
ATOM   3553 C CA    . HIS A 1 466 ? -16.507 21.199  -7.279  1.000 20.711  0 465  HIS A CA    1 ? 
ATOM   3554 C C     . HIS A 1 466 ? -15.192 20.418  -7.368  1.000 21.295  0 465  HIS A C     1 ? 
ATOM   3555 O O     . HIS A 1 466 ? -14.680 19.905  -6.387  1.000 19.228  0 465  HIS A O     1 ? 
ATOM   3556 C CB    . HIS A 1 466 ? -17.710 20.342  -7.687  1.000 24.406  0 465  HIS A CB    1 ? 
ATOM   3557 C CG    . HIS A 1 466 ? -17.923 19.248  -6.711  1.000 28.657  0 465  HIS A CG    1 ? 
ATOM   3558 N ND1   . HIS A 1 466 ? -17.753 17.918  -7.024  1.000 31.120  0 465  HIS A ND1   1 ? 
ATOM   3559 C CD2   . HIS A 1 466 ? -18.268 19.275  -5.405  1.000 33.874  0 465  HIS A CD2   1 ? 
ATOM   3560 C CE1   . HIS A 1 466 ? -18.038 17.167  -5.944  1.000 31.309  0 465  HIS A CE1   1 ? 
ATOM   3561 N NE2   . HIS A 1 466 ? -18.324 17.962  -4.934  1.000 31.783  0 465  HIS A NE2   1 ? 
ATOM   3562 N N     . ALA A 1 467 ? -14.633 20.319  -8.566  1.000 18.566  0 466  ALA A N     1 ? 
ATOM   3563 C CA    . ALA A 1 467 ? -13.407 19.564  -8.762  1.000 17.842  0 466  ALA A CA    1 ? 
ATOM   3564 C C     . ALA A 1 467 ? -12.229 20.216  -8.012  1.000 17.991  0 466  ALA A C     1 ? 
ATOM   3565 O O     . ALA A 1 467 ? -11.384 19.531  -7.448  1.000 19.702  0 466  ALA A O     1 ? 
ATOM   3566 C CB    . ALA A 1 467 ? -13.179 19.422  -10.251 1.000 18.297  0 466  ALA A CB    1 ? 
ATOM   3567 N N     . ALA A 1 468 ? -12.180 21.542  -7.957  1.000 19.143  0 467  ALA A N     1 ? 
ATOM   3568 C CA    . ALA A 1 468 ? -11.150 22.216  -7.172  1.000 20.264  0 467  ALA A CA    1 ? 
ATOM   3569 C C     . ALA A 1 468 ? -11.267 21.875  -5.679  1.000 18.705  0 467  ALA A C     1 ? 
ATOM   3570 O O     . ALA A 1 468 ? -10.263 21.622  -5.008  1.000 18.762  0 467  ALA A O     1 ? 
ATOM   3571 C CB    . ALA A 1 468 ? -11.211 23.703  -7.395  1.000 22.944  0 467  ALA A CB    1 ? 
ATOM   3572 N N     . ARG A 1 469 ? -12.495 21.779  -5.177  1.000 19.338  0 468  ARG A N     1 ? 
ATOM   3573 C CA    . ARG A 1 469 ? -12.714 21.405  -3.780  1.000 18.530  0 468  ARG A CA    1 ? 
ATOM   3574 C C     . ARG A 1 469 ? -12.282 19.961  -3.558  1.000 18.731  0 468  ARG A C     1 ? 
ATOM   3575 O O     . ARG A 1 469 ? -11.667 19.608  -2.557  1.000 21.539  0 468  ARG A O     1 ? 
ATOM   3576 C CB    . ARG A 1 469 ? -14.189 21.550  -3.389  1.000 18.709  0 468  ARG A CB    1 ? 
ATOM   3577 C CG    . ARG A 1 469 ? -14.636 22.995  -3.273  1.000 22.400  0 468  ARG A CG    1 ? 
ATOM   3578 C CD    . ARG A 1 469 ? -15.832 23.203  -2.358  1.000 23.755  0 468  ARG A CD    1 ? 
ATOM   3579 N NE    . ARG A 1 469 ? -16.242 24.611  -2.340  1.000 22.905  0 468  ARG A NE    1 ? 
ATOM   3580 C CZ    . ARG A 1 469 ? -17.034 25.173  -3.217  1.000 23.297  0 468  ARG A CZ    1 ? 
ATOM   3581 N NH1   . ARG A 1 469 ? -17.671 24.429  -4.103  1.000 23.261  0 468  ARG A NH1   1 ? 
ATOM   3582 N NH2   . ARG A 1 469 ? -17.297 26.470  -3.145  1.000 25.590  0 468  ARG A NH2   1 ? 
ATOM   3583 N N     . LEU A 1 470 ? -12.537 19.105  -4.524  1.000 18.533  0 469  LEU A N     1 ? 
ATOM   3584 C CA    . LEU A 1 470 ? -12.133 17.717  -4.397  1.000 18.967  0 469  LEU A CA    1 ? 
ATOM   3585 C C     . LEU A 1 470 ? -10.607 17.604  -4.367  1.000 20.021  0 469  LEU A C     1 ? 
ATOM   3586 O O     . LEU A 1 470 ? -10.057 16.778  -3.648  1.000 18.886  0 469  LEU A O     1 ? 
ATOM   3587 C CB    . LEU A 1 470 ? -12.702 16.863  -5.523  1.000 21.023  0 469  LEU A CB    1 ? 
ATOM   3588 C CG    . LEU A 1 470 ? -14.218 16.632  -5.514  1.000 22.158  0 469  LEU A CG    1 ? 
ATOM   3589 C CD1   . LEU A 1 470 ? -14.566 15.714  -6.666  1.000 24.404  0 469  LEU A CD1   1 ? 
ATOM   3590 C CD2   . LEU A 1 470 ? -14.678 16.025  -4.204  1.000 22.124  0 469  LEU A CD2   1 ? 
ATOM   3591 N N     . ALA A 1 471 ? -9.928  18.398  -5.195  1.000 18.253  0 470  ALA A N     1 ? 
ATOM   3592 C CA    . ALA A 1 471 ? -8.479  18.395  -5.199  1.000 20.435  0 470  ALA A CA    1 ? 
ATOM   3593 C C     . ALA A 1 471 ? -7.959  18.742  -3.806  1.000 21.024  0 470  ALA A C     1 ? 
ATOM   3594 O O     . ALA A 1 471 ? -6.994  18.135  -3.344  1.000 23.134  0 470  ALA A O     1 ? 
ATOM   3595 C CB    . ALA A 1 471 ? -7.949  19.379  -6.225  1.000 20.381  0 470  ALA A CB    1 ? 
ATOM   3596 N N     . ARG A 1 472 ? -8.529  19.787  -3.203  1.000 19.743  0 471  ARG A N     1 ? 
ATOM   3597 C CA    . ARG A 1 472 ? -8.085  20.218  -1.884  1.000 20.032  0 471  ARG A CA    1 ? 
ATOM   3598 C C     . ARG A 1 472 ? -8.400  19.133  -0.854  1.000 20.003  0 471  ARG A C     1 ? 
ATOM   3599 O O     . ARG A 1 472 ? -7.577  18.870  -0.005  1.000 20.533  0 471  ARG A O     1 ? 
ATOM   3600 C CB    . ARG A 1 472 ? -8.685  21.532  -1.389  1.000 21.526  0 471  ARG A CB    1 ? 
ATOM   3601 C CG    . ARG A 1 472 ? -8.268  22.692  -2.282  1.000 21.311  0 471  ARG A CG    1 ? 
ATOM   3602 C CD    . ARG A 1 472 ? -9.110  23.892  -1.906  1.000 22.635  0 471  ARG A CD    1 ? 
ATOM   3603 N NE    . ARG A 1 472 ? -8.704  25.035  -2.730  1.000 21.735  0 471  ARG A NE    1 ? 
ATOM   3604 C CZ    . ARG A 1 472 ? -9.058  26.305  -2.561  1.000 22.226  0 471  ARG A CZ    1 ? 
ATOM   3605 N NH1   . ARG A 1 472 ? -9.850  26.663  -1.566  1.000 21.817  0 471  ARG A NH1   1 ? 
ATOM   3606 N NH2   . ARG A 1 472 ? -8.593  27.217  -3.406  1.000 20.966  0 471  ARG A NH2   1 ? 
ATOM   3607 N N     . GLN A 1 473 ? -9.577  18.485  -0.943  1.000 22.245  0 472  GLN A N     1 ? 
ATOM   3608 C CA    . GLN A 1 473 ? -9.902  17.387  -0.025  1.000 21.013  0 472  GLN A CA    1 ? 
ATOM   3609 C C     . GLN A 1 473 ? -8.961  16.197  -0.232  1.000 19.982  0 472  GLN A C     1 ? 
ATOM   3610 O O     . GLN A 1 473 ? -8.584  15.514  0.710   1.000 19.660  0 472  GLN A O     1 ? 
ATOM   3611 C CB    . GLN A 1 473 ? -11.350 16.950  -0.186  1.000 23.029  0 472  GLN A CB    1 ? 
ATOM   3612 C CG    . GLN A 1 473 ? -12.353 17.970  0.316   1.000 29.498  0 472  GLN A CG    1 ? 
ATOM   3613 C CD    . GLN A 1 473 ? -13.724 17.825  -0.304  1.000 32.925  0 472  GLN A CD    1 ? 
ATOM   3614 O OE1   . GLN A 1 473 ? -14.232 16.721  -0.585  1.000 33.116  0 472  GLN A OE1   1 ? 
ATOM   3615 N NE2   . GLN A 1 473 ? -14.304 18.983  -0.572  1.000 32.149  0 472  GLN A NE2   1 ? 
ATOM   3616 N N     . PHE A 1 474 ? -8.643  15.863  -1.484  1.000 17.683  0 473  PHE A N     1 ? 
ATOM   3617 C CA    . PHE A 1 474 ? -7.786  14.721  -1.753  1.000 19.219  0 473  PHE A CA    1 ? 
ATOM   3618 C C     . PHE A 1 474 ? -6.455  14.851  -1.013  1.000 20.285  0 473  PHE A C     1 ? 
ATOM   3619 O O     . PHE A 1 474 ? -5.962  13.891  -0.432  1.000 22.019  0 473  PHE A O     1 ? 
ATOM   3620 C CB    . PHE A 1 474 ? -7.540  14.563  -3.251  1.000 19.132  0 473  PHE A CB    1 ? 
ATOM   3621 C CG    . PHE A 1 474 ? -6.632  13.386  -3.568  1.000 20.585  0 473  PHE A CG    1 ? 
ATOM   3622 C CD1   . PHE A 1 474 ? -6.925  12.104  -3.091  1.000 21.354  0 473  PHE A CD1   1 ? 
ATOM   3623 C CD2   . PHE A 1 474 ? -5.424  13.601  -4.210  1.000 19.608  0 473  PHE A CD2   1 ? 
ATOM   3624 C CE1   . PHE A 1 474 ? -6.058  11.046  -3.339  1.000 20.813  0 473  PHE A CE1   1 ? 
ATOM   3625 C CE2   . PHE A 1 474 ? -4.582  12.535  -4.488  1.000 21.559  0 473  PHE A CE2   1 ? 
ATOM   3626 C CZ    . PHE A 1 474 ? -4.917  11.255  -4.080  1.000 20.905  0 473  PHE A CZ    1 ? 
ATOM   3627 N N     . VAL A 1 475 ? -5.854  16.044  -1.018  1.000 18.649  0 474  VAL A N     1 ? 
ATOM   3628 C CA    . VAL A 1 475 ? -4.535  16.166  -0.447  1.000 19.881  0 474  VAL A CA    1 ? 
ATOM   3629 C C     . VAL A 1 475 ? -4.605  16.498  1.050   1.000 20.370  0 474  VAL A C     1 ? 
ATOM   3630 O O     . VAL A 1 475 ? -3.594  16.918  1.601   1.000 21.516  0 474  VAL A O     1 ? 
ATOM   3631 C CB    . VAL A 1 475 ? -3.666  17.174  -1.203  1.000 22.399  0 474  VAL A CB    1 ? 
ATOM   3632 C CG1   . VAL A 1 475 ? -3.484  16.732  -2.654  1.000 23.525  0 474  VAL A CG1   1 ? 
ATOM   3633 C CG2   . VAL A 1 475 ? -4.198  18.594  -1.106  1.000 22.734  0 474  VAL A CG2   1 ? 
ATOM   3634 N N     . SER A 1 476 ? -5.775  16.369  1.671   1.000 22.700  0 475  SER A N     1 ? 
ATOM   3635 C CA    . SER A 1 476 ? -5.903  16.675  3.099   1.000 25.894  0 475  SER A CA    1 ? 
ATOM   3636 C C     . SER A 1 476 ? -5.781  15.409  3.944   1.000 26.007  0 475  SER A C     1 ? 
ATOM   3637 O O     . SER A 1 476 ? -5.789  15.492  5.167   1.000 24.588  0 475  SER A O     1 ? 
ATOM   3638 C CB    . SER A 1 476 ? -7.204  17.428  3.416   1.000 26.408  0 475  SER A CB    1 ? 
ATOM   3639 O OG    . SER A 1 476 ? -8.336  16.570  3.320   1.000 30.227  0 475  SER A OG    1 ? 
ATOM   3640 N N     . SER A 1 477 ? -5.693  14.227  3.332   1.000 24.908  0 476  SER A N     1 ? 
ATOM   3641 C CA    . SER A 1 477 ? -5.595  13.001  4.111   1.000 26.307  0 476  SER A CA    1 ? 
ATOM   3642 C C     . SER A 1 477 ? -4.168  12.819  4.615   1.000 24.648  0 476  SER A C     1 ? 
ATOM   3643 O O     . SER A 1 477 ? -3.219  13.478  4.175   1.000 21.396  0 476  SER A O     1 ? 
ATOM   3644 C CB    . SER A 1 477 ? -6.036  11.815  3.316   1.000 26.855  0 476  SER A CB    1 ? 
ATOM   3645 O OG    . SER A 1 477 ? -5.307  11.796  2.109   1.000 27.380  0 476  SER A OG    1 ? 
ATOM   3646 N N     . SER A 1 478 ? -4.003  11.922  5.592   1.000 26.035  0 477  SER A N     1 ? 
ATOM   3647 C CA    . SER A 1 478 ? -2.740  11.850  6.309   1.000 28.865  0 477  SER A CA    1 ? 
ATOM   3648 C C     . SER A 1 478 ? -1.551  11.462  5.418   1.000 25.082  0 477  SER A C     1 ? 
ATOM   3649 O O     . SER A 1 478 ? -0.459  11.989  5.619   1.000 24.266  0 477  SER A O     1 ? 
ATOM   3650 C CB    . SER A 1 478 ? -2.849  10.979  7.561   1.000 31.410  0 477  SER A CB    1 ? 
ATOM   3651 O OG    . SER A 1 478 ? -3.002  9.620   7.203   1.000 36.303  0 477  SER A OG    1 ? 
ATOM   3652 N N     . PRO A 1 479 ? -1.637  10.613  4.366   1.000 25.892  0 478  PRO A N     1 ? 
ATOM   3653 C CA    . PRO A 1 479 ? -0.466  10.375  3.523   1.000 23.154  0 478  PRO A CA    1 ? 
ATOM   3654 C C     . PRO A 1 479 ? 0.066   11.625  2.824   1.000 23.601  0 478  PRO A C     1 ? 
ATOM   3655 O O     . PRO A 1 479 ? 1.239   11.685  2.434   1.000 25.418  0 478  PRO A O     1 ? 
ATOM   3656 C CB    . PRO A 1 479 ? -0.967  9.305   2.506   1.000 24.089  0 478  PRO A CB    1 ? 
ATOM   3657 C CG    . PRO A 1 479 ? -2.191  8.712   3.163   1.000 26.667  0 478  PRO A CG    1 ? 
ATOM   3658 C CD    . PRO A 1 479 ? -2.813  9.829   3.956   1.000 27.150  0 478  PRO A CD    1 ? 
ATOM   3659 N N     . TRP A 1 480 ? -0.794  12.644  2.677   1.000 20.658  0 479  TRP A N     1 ? 
ATOM   3660 C CA    . TRP A 1 480 ? -0.378  13.896  2.064   1.000 22.934  0 479  TRP A CA    1 ? 
ATOM   3661 C C     . TRP A 1 480 ? 0.046   14.939  3.103   1.000 27.588  0 479  TRP A C     1 ? 
ATOM   3662 O O     . TRP A 1 480 ? 0.572   15.974  2.723   1.000 29.531  0 479  TRP A O     1 ? 
ATOM   3663 C CB    . TRP A 1 480 ? -1.499  14.448  1.172   1.000 22.481  0 479  TRP A CB    1 ? 
ATOM   3664 C CG    . TRP A 1 480 ? -1.818  13.559  0.003   1.000 20.629  0 479  TRP A CG    1 ? 
ATOM   3665 C CD1   . TRP A 1 480 ? -2.917  12.776  -0.186  1.000 22.380  0 479  TRP A CD1   1 ? 
ATOM   3666 C CD2   . TRP A 1 480 ? -1.017  13.427  -1.187  1.000 21.955  0 479  TRP A CD2   1 ? 
ATOM   3667 N NE1   . TRP A 1 480 ? -2.843  12.137  -1.397  1.000 24.020  0 479  TRP A NE1   1 ? 
ATOM   3668 C CE2   . TRP A 1 480 ? -1.685  12.519  -2.032  1.000 21.126  0 479  TRP A CE2   1 ? 
ATOM   3669 C CE3   . TRP A 1 480 ? 0.205   13.970  -1.593  1.000 21.573  0 479  TRP A CE3   1 ? 
ATOM   3670 C CZ2   . TRP A 1 480 ? -1.179  12.144  -3.271  1.000 21.296  0 479  TRP A CZ2   1 ? 
ATOM   3671 C CZ3   . TRP A 1 480 ? 0.681   13.637  -2.840  1.000 22.965  0 479  TRP A CZ3   1 ? 
ATOM   3672 C CH2   . TRP A 1 480 ? 0.013   12.714  -3.648  1.000 23.354  0 479  TRP A CH2   1 ? 
ATOM   3673 N N     . ALA A 1 481 ? -0.106  14.648  4.404   1.000 29.128  0 480  ALA A N     1 ? 
ATOM   3674 C CA    . ALA A 1 481 ? -0.028  15.689  5.432   1.000 34.061  0 480  ALA A CA    1 ? 
ATOM   3675 C C     . ALA A 1 481 ? 1.384   16.256  5.563   1.000 34.992  0 480  ALA A C     1 ? 
ATOM   3676 O O     . ALA A 1 481 ? 1.543   17.451  5.807   1.000 38.573  0 480  ALA A O     1 ? 
ATOM   3677 C CB    . ALA A 1 481 ? -0.494  15.162  6.772   1.000 33.627  0 480  ALA A CB    1 ? 
ATOM   3678 N N     . ASP A 1 482 ? 2.407   15.413  5.426   1.000 32.681  0 481  ASP A N     1 ? 
ATOM   3679 C CA    . ASP A 1 482 ? 3.769   15.900  5.571   1.000 35.937  0 481  ASP A CA    1 ? 
ATOM   3680 C C     . ASP A 1 482 ? 4.285   16.490  4.260   1.000 36.754  0 481  ASP A C     1 ? 
ATOM   3681 O O     . ASP A 1 482 ? 5.280   17.197  4.297   1.000 37.905  0 481  ASP A O     1 ? 
ATOM   3682 C CB    . ASP A 1 482 ? 4.652   14.844  6.212   1.000 45.153  0 481  ASP A CB    1 ? 
ATOM   3683 C CG    . ASP A 1 482 ? 4.349   14.621  7.694   1.000 54.193  0 481  ASP A CG    1 ? 
ATOM   3684 O OD1   . ASP A 1 482 ? 4.581   15.561  8.505   1.000 52.664  0 481  ASP A OD1   1 ? 
ATOM   3685 O OD2   . ASP A 1 482 ? 3.844   13.526  8.035   1.000 59.523  0 481  ASP A OD2   1 ? 
ATOM   3686 N N     . PHE A 1 483 ? 3.586   16.251  3.134   1.000 27.336  0 482  PHE A N     1 ? 
ATOM   3687 C CA    . PHE A 1 483 ? 4.105   16.585  1.812   1.000 23.612  0 482  PHE A CA    1 ? 
ATOM   3688 C C     . PHE A 1 483 ? 3.576   17.936  1.344   1.000 24.687  0 482  PHE A C     1 ? 
ATOM   3689 O O     . PHE A 1 483 ? 4.336   18.783  0.881   1.000 23.340  0 482  PHE A O     1 ? 
ATOM   3690 C CB    . PHE A 1 483 ? 3.733   15.416  0.891   1.000 23.453  0 482  PHE A CB    1 ? 
ATOM   3691 C CG    . PHE A 1 483 ? 4.299   15.480  -0.521  1.000 21.430  0 482  PHE A CG    1 ? 
ATOM   3692 C CD1   . PHE A 1 483 ? 5.628   15.139  -0.778  1.000 22.809  0 482  PHE A CD1   1 ? 
ATOM   3693 C CD2   . PHE A 1 483 ? 3.526   15.953  -1.577  1.000 23.076  0 482  PHE A CD2   1 ? 
ATOM   3694 C CE1   . PHE A 1 483 ? 6.143   15.198  -2.068  1.000 21.883  0 482  PHE A CE1   1 ? 
ATOM   3695 C CE2   . PHE A 1 483 ? 4.048   16.000  -2.861  1.000 22.260  0 482  PHE A CE2   1 ? 
ATOM   3696 C CZ    . PHE A 1 483 ? 5.366   15.653  -3.102  1.000 20.905  0 482  PHE A CZ    1 ? 
ATOM   3697 N N     . VAL A 1 484 ? 2.250   18.106  1.393   1.000 23.220  0 483  VAL A N     1 ? 
ATOM   3698 C CA    . VAL A 1 484 ? 1.632   19.344  0.988   1.000 25.978  0 483  VAL A CA    1 ? 
ATOM   3699 C C     . VAL A 1 484 ? 1.762   20.343  2.121   1.000 27.688  0 483  VAL A C     1 ? 
ATOM   3700 O O     . VAL A 1 484 ? 1.332   20.057  3.238   1.000 30.280  0 483  VAL A O     1 ? 
ATOM   3701 C CB    . VAL A 1 484 ? 0.167   19.093  0.632   1.000 29.556  0 483  VAL A CB    1 ? 
ATOM   3702 C CG1   . VAL A 1 484 ? -0.578  20.412  0.557   1.000 33.408  0 483  VAL A CG1   1 ? 
ATOM   3703 C CG2   . VAL A 1 484 ? 0.059   18.257  -0.645  1.000 30.387  0 483  VAL A CG2   1 ? 
ATOM   3704 N N     . GLU A 1 485 ? 2.286   21.518  1.793   1.000 27.210  0 484  GLU A N     1 ? 
ATOM   3705 C CA    . GLU A 1 485 ? 2.514   22.576  2.771   1.000 30.984  0 484  GLU A CA    1 ? 
ATOM   3706 C C     . GLU A 1 485 ? 1.504   23.704  2.669   1.000 32.664  0 484  GLU A C     1 ? 
ATOM   3707 O O     . GLU A 1 485 ? 1.119   24.266  3.684   1.000 36.103  0 484  GLU A O     1 ? 
ATOM   3708 C CB    . GLU A 1 485 ? 3.836   23.295  2.562   1.000 33.367  0 484  GLU A CB    1 ? 
ATOM   3709 C CG    . GLU A 1 485 ? 5.005   22.372  2.833   1.000 39.062  0 484  GLU A CG    1 ? 
ATOM   3710 C CD    . GLU A 1 485 ? 6.324   23.122  2.844   1.000 39.961  0 484  GLU A CD    1 ? 
ATOM   3711 O OE1   . GLU A 1 485 ? 6.689   23.806  1.854   1.000 36.507  0 484  GLU A OE1   1 ? 
ATOM   3712 O OE2   . GLU A 1 485 ? 6.988   22.971  3.890   1.000 45.762  0 484  GLU A OE2   1 ? 
ATOM   3713 N N     . SER A 1 486 ? 1.140   24.115  1.457   1.000 27.166  0 485  SER A N     1 ? 
ATOM   3714 C CA    . SER A 1 486 ? 0.162   25.182  1.308   1.000 27.933  0 485  SER A CA    1 ? 
ATOM   3715 C C     . SER A 1 486 ? -0.291  25.245  -0.144  1.000 26.053  0 485  SER A C     1 ? 
ATOM   3716 O O     . SER A 1 486 ? 0.329   24.637  -1.007  1.000 24.816  0 485  SER A O     1 ? 
ATOM   3717 C CB    . SER A 1 486 ? 0.731   26.523  1.737   1.000 31.954  0 485  SER A CB    1 ? 
ATOM   3718 O OG    . SER A 1 486 ? 1.896   26.789  0.985   1.000 33.140  0 485  SER A OG    1 ? 
ATOM   3719 N N     . ARG A 1 487 ? -1.362  25.995  -0.369  1.000 25.063  0 486  ARG A N     1 ? 
ATOM   3720 C CA    . ARG A 1 487 ? -1.898  26.242  -1.697  1.000 24.743  0 486  ARG A CA    1 ? 
ATOM   3721 C C     . ARG A 1 487 ? -1.296  27.528  -2.225  1.000 25.510  0 486  ARG A C     1 ? 
ATOM   3722 O O     . ARG A 1 487 ? -0.935  28.408  -1.445  1.000 22.920  0 486  ARG A O     1 ? 
ATOM   3723 C CB    . ARG A 1 487 ? -3.404  26.458  -1.625  1.000 24.904  0 486  ARG A CB    1 ? 
ATOM   3724 C CG    . ARG A 1 487 ? -4.087  25.387  -0.810  1.000 26.277  0 486  ARG A CG    1 ? 
ATOM   3725 C CD    . ARG A 1 487 ? -5.571  25.398  -1.100  1.000 28.689  0 486  ARG A CD    1 ? 
ATOM   3726 N NE    . ARG A 1 487 ? -6.193  26.700  -0.871  1.000 26.744  0 486  ARG A NE    1 ? 
ATOM   3727 C CZ    . ARG A 1 487 ? -6.927  27.045  0.166   1.000 32.348  0 486  ARG A CZ    1 ? 
ATOM   3728 N NH1   . ARG A 1 487 ? -7.181  26.166  1.119   1.000 32.154  0 486  ARG A NH1   1 ? 
ATOM   3729 N NH2   . ARG A 1 487 ? -7.382  28.289  0.269   1.000 30.870  0 486  ARG A NH2   1 ? 
ATOM   3730 N N     . THR A 1 488 ? -1.218  27.652  -3.545  1.000 22.791  0 487  THR A N     1 ? 
ATOM   3731 C CA    . THR A 1 488 ? -0.727  28.880  -4.136  1.000 23.866  0 487  THR A CA    1 ? 
ATOM   3732 C C     . THR A 1 488 ? -1.236  28.956  -5.579  1.000 22.720  0 487  THR A C     1 ? 
ATOM   3733 O O     . THR A 1 488 ? -1.899  28.042  -6.037  1.000 22.986  0 487  THR A O     1 ? 
ATOM   3734 C CB    . THR A 1 488 ? 0.800   28.886  -3.995  1.000 26.254  0 487  THR A CB    1 ? 
ATOM   3735 O OG1   . THR A 1 488 ? 1.169   30.182  -4.447  1.000 27.035  0 487  THR A OG1   1 ? 
ATOM   3736 C CG2   . THR A 1 488 ? 1.484   27.783  -4.776  1.000 28.540  0 487  THR A CG2   1 ? 
ATOM   3737 N N     . GLY A 1 489 ? -0.959  30.055  -6.285  1.000 22.128  0 488  GLY A N     1 ? 
ATOM   3738 C CA    . GLY A 1 489 ? -1.482  30.250  -7.632  1.000 21.037  0 488  GLY A CA    1 ? 
ATOM   3739 C C     . GLY A 1 489 ? -2.908  30.784  -7.583  1.000 19.218  0 488  GLY A C     1 ? 
ATOM   3740 O O     . GLY A 1 489 ? -3.485  30.954  -6.530  1.000 19.697  0 488  GLY A O     1 ? 
ATOM   3741 N N     . ILE A 1 490 ? -3.470  31.055  -8.751  1.000 19.903  0 489  ILE A N     1 ? 
ATOM   3742 C CA    . ILE A 1 490 ? -4.754  31.723  -8.852  1.000 20.694  0 489  ILE A CA    1 ? 
ATOM   3743 C C     . ILE A 1 490 ? -5.825  31.008  -8.020  1.000 20.758  0 489  ILE A C     1 ? 
ATOM   3744 O O     . ILE A 1 490 ? -6.509  31.630  -7.196  1.000 21.224  0 489  ILE A O     1 ? 
ATOM   3745 C CB    . ILE A 1 490 ? -5.167  31.811  -10.330 1.000 19.218  0 489  ILE A CB    1 ? 
ATOM   3746 C CG1   . ILE A 1 490 ? -4.202  32.682  -11.124 1.000 22.251  0 489  ILE A CG1   1 ? 
ATOM   3747 C CG2   . ILE A 1 490 ? -6.604  32.323  -10.431 1.000 21.135  0 489  ILE A CG2   1 ? 
ATOM   3748 C CD1   . ILE A 1 490 ? -4.439  32.728  -12.625 1.000 20.596  0 489  ILE A CD1   1 ? 
ATOM   3749 N N     . ILE A 1 491 ? -6.039  29.717  -8.289  1.000 19.175  0 490  ILE A N     1 ? 
ATOM   3750 C CA    . ILE A 1 491 ? -7.100  29.004  -7.596  1.000 18.908  0 490  ILE A CA    1 ? 
ATOM   3751 C C     . ILE A 1 491 ? -6.697  28.803  -6.139  1.000 19.996  0 490  ILE A C     1 ? 
ATOM   3752 O O     . ILE A 1 491 ? -7.470  29.086  -5.220  1.000 20.279  0 490  ILE A O     1 ? 
ATOM   3753 C CB    . ILE A 1 491 ? -7.440  27.652  -8.265  1.000 19.377  0 490  ILE A CB    1 ? 
ATOM   3754 C CG1   . ILE A 1 491 ? -7.834  27.808  -9.707  1.000 18.513  0 490  ILE A CG1   1 ? 
ATOM   3755 C CG2   . ILE A 1 491 ? -8.531  26.925  -7.491  1.000 19.864  0 490  ILE A CG2   1 ? 
ATOM   3756 C CD1   . ILE A 1 491 ? -9.082  28.646  -9.886  1.000 22.001  0 490  ILE A CD1   1 ? 
ATOM   3757 N N     . GLY A 1 492 ? -5.485  28.287  -5.928  1.000 22.691  0 491  GLY A N     1 ? 
ATOM   3758 C CA    . GLY A 1 492 ? -5.050  27.949  -4.584  1.000 21.339  0 491  GLY A CA    1 ? 
ATOM   3759 C C     . GLY A 1 492 ? -5.097  29.136  -3.624  1.000 23.093  0 491  GLY A C     1 ? 
ATOM   3760 O O     . GLY A 1 492 ? -5.353  28.957  -2.424  1.000 23.802  0 491  GLY A O     1 ? 
ATOM   3761 N N     . ASP A 1 493 ? -4.792  30.350  -4.108  1.000 22.055  0 492  ASP A N     1 ? 
ATOM   3762 C CA    . ASP A 1 493 ? -4.842  31.522  -3.226  1.000 21.801  0 492  ASP A CA    1 ? 
ATOM   3763 C C     . ASP A 1 493 ? -6.278  31.924  -2.883  1.000 23.345  0 492  ASP A C     1 ? 
ATOM   3764 O O     . ASP A 1 493 ? -6.498  32.827  -2.088  1.000 23.239  0 492  ASP A O     1 ? 
ATOM   3765 C CB    . ASP A 1 493 ? -4.207  32.744  -3.877  1.000 24.802  0 492  ASP A CB    1 ? 
ATOM   3766 C CG    . ASP A 1 493 ? -2.688  32.750  -4.039  1.000 26.924  0 492  ASP A CG    1 ? 
ATOM   3767 O OD1   . ASP A 1 493 ? -2.048  31.915  -3.400  1.000 25.771  0 492  ASP A OD1   1 ? 
ATOM   3768 O OD2   . ASP A 1 493 ? -2.186  33.550  -4.889  1.000 34.118  0 492  ASP A OD2   1 ? 
ATOM   3769 N N     . THR A 1 494 ? -7.263  31.348  -3.547  1.000 22.216  0 493  THR A N     1 ? 
ATOM   3770 C CA    . THR A 1 494 ? -8.654  31.752  -3.374  1.000 22.377  0 493  THR A CA    1 ? 
ATOM   3771 C C     . THR A 1 494 ? -9.258  30.953  -2.223  1.000 23.224  0 493  THR A C     1 ? 
ATOM   3772 O O     . THR A 1 494 ? -9.027  29.751  -2.097  1.000 22.074  0 493  THR A O     1 ? 
ATOM   3773 C CB    . THR A 1 494 ? -9.403  31.499  -4.684  1.000 24.131  0 493  THR A CB    1 ? 
ATOM   3774 O OG1   . THR A 1 494 ? -8.764  32.250  -5.716  1.000 22.085  0 493  THR A OG1   1 ? 
ATOM   3775 C CG2   . THR A 1 494 ? -10.868 31.908  -4.599  1.000 24.474  0 493  THR A CG2   1 ? 
ATOM   3776 N N     . ASP A 1 495 ? -10.079 31.610  -1.406  1.000 25.030  0 494  ASP A N     1 ? 
ATOM   3777 C CA    . ASP A 1 495 ? -10.778 30.916  -0.331  1.000 27.284  0 494  ASP A CA    1 ? 
ATOM   3778 C C     . ASP A 1 495 ? -11.862 30.013  -0.925  1.000 26.790  0 494  ASP A C     1 ? 
ATOM   3779 O O     . ASP A 1 495 ? -12.026 29.928  -2.131  1.000 27.693  0 494  ASP A O     1 ? 
ATOM   3780 C CB    . ASP A 1 495 ? -11.273 31.903  0.711   1.000 30.782  0 494  ASP A CB    1 ? 
ATOM   3781 C CG    . ASP A 1 495 ? -12.376 32.844  0.259   1.000 37.567  0 494  ASP A CG    1 ? 
ATOM   3782 O OD1   . ASP A 1 495 ? -12.967 32.601  -0.828  1.000 36.314  0 494  ASP A OD1   1 ? 
ATOM   3783 O OD2   . ASP A 1 495 ? -12.610 33.832  0.986   1.000 38.401  0 494  ASP A OD2   1 ? 
ATOM   3784 N N     . ASP A 1 496 ? -12.628 29.337  -0.072  1.000 25.732  0 495  ASP A N     1 ? 
ATOM   3785 C CA    . ASP A 1 496 ? -13.498 28.257  -0.488  1.000 26.819  0 495  ASP A CA    1 ? 
ATOM   3786 C C     . ASP A 1 496 ? -14.857 28.744  -1.005  1.000 26.843  0 495  ASP A C     1 ? 
ATOM   3787 O O     . ASP A 1 496 ? -15.682 27.941  -1.430  1.000 27.664  0 495  ASP A O     1 ? 
ATOM   3788 C CB    . ASP A 1 496 ? -13.721 27.337  0.705   1.000 30.239  0 495  ASP A CB    1 ? 
ATOM   3789 C CG    . ASP A 1 496 ? -14.441 26.046  0.376   1.000 35.103  0 495  ASP A CG    1 ? 
ATOM   3790 O OD1   . ASP A 1 496 ? -13.779 25.135  -0.166  1.000 40.230  0 495  ASP A OD1   1 ? 
ATOM   3791 O OD2   . ASP A 1 496 ? -15.650 25.989  0.664   1.000 35.236  0 495  ASP A OD2   1 ? 
ATOM   3792 N N     . ASP A 1 497 ? -15.134 30.039  -0.922  1.000 24.329  0 496  ASP A N     1 ? 
ATOM   3793 C CA    . ASP A 1 497 ? -16.456 30.537  -1.253  1.000 25.963  0 496  ASP A CA    1 ? 
ATOM   3794 C C     . ASP A 1 497 ? -16.714 30.366  -2.753  1.000 26.521  0 496  ASP A C     1 ? 
ATOM   3795 O O     . ASP A 1 497 ? -15.852 30.683  -3.543  1.000 25.385  0 496  ASP A O     1 ? 
ATOM   3796 C CB    . ASP A 1 497 ? -16.616 31.973  -0.791  1.000 28.568  0 496  ASP A CB    1 ? 
ATOM   3797 C CG    . ASP A 1 497 ? -17.881 32.616  -1.341  1.000 37.048  0 496  ASP A CG    1 ? 
ATOM   3798 O OD1   . ASP A 1 497 ? -18.986 32.234  -0.878  1.000 36.054  0 496  ASP A OD1   1 ? 
ATOM   3799 O OD2   . ASP A 1 497 ? -17.755 33.378  -2.324  1.000 36.996  0 496  ASP A OD2   1 ? 
ATOM   3800 N N     . GLU A 1 498 ? -17.902 29.858  -3.115  1.000 23.986  0 497  GLU A N     1 ? 
ATOM   3801 C CA    . GLU A 1 498 ? -18.297 29.585  -4.492  1.000 24.226  0 497  GLU A CA    1 ? 
ATOM   3802 C C     . GLU A 1 498 ? -18.077 30.777  -5.434  1.000 26.187  0 497  GLU A C     1 ? 
ATOM   3803 O O     . GLU A 1 498 ? -17.555 30.578  -6.526  1.000 26.720  0 497  GLU A O     1 ? 
ATOM   3804 C CB    . GLU A 1 498 ? -19.769 29.189  -4.566  1.000 26.954  0 497  GLU A CB    1 ? 
ATOM   3805 C CG    . GLU A 1 498 ? -20.182 28.648  -5.933  1.000 29.862  0 497  GLU A CG    1 ? 
ATOM   3806 C CD    . GLU A 1 498 ? -19.721 27.218  -6.183  1.000 34.591  0 497  GLU A CD    1 ? 
ATOM   3807 O OE1   . GLU A 1 498 ? -19.265 26.512  -5.219  1.000 31.922  0 497  GLU A OE1   1 ? 
ATOM   3808 O OE2   . GLU A 1 498 ? -19.840 26.812  -7.368  1.000 33.157  0 497  GLU A OE2   1 ? 
ATOM   3809 N N     . ALA A 1 499 ? -18.551 31.996  -5.089  1.000 26.243  0 498  ALA A N     1 ? 
ATOM   3810 C CA    . ALA A 1 499 ? -18.410 33.133  -6.000  1.000 27.901  0 498  ALA A CA    1 ? 
ATOM   3811 C C     . ALA A 1 499 ? -16.927 33.467  -6.195  1.000 27.255  0 498  ALA A C     1 ? 
ATOM   3812 O O     . ALA A 1 499 ? -16.494 33.808  -7.295  1.000 25.344  0 498  ALA A O     1 ? 
ATOM   3813 C CB    . ALA A 1 499 ? -19.203 34.343  -5.510  1.000 30.396  0 498  ALA A CB    1 ? 
ATOM   3814 N N     . ASP A 1 500 ? -16.150 33.385  -5.112  1.000 25.756  0 499  ASP A N     1 ? 
ATOM   3815 C CA    . ASP A 1 500 ? -14.713 33.636  -5.163  1.000 23.958  0 499  ASP A CA    1 ? 
ATOM   3816 C C     . ASP A 1 500 ? -14.043 32.621  -6.093  1.000 24.190  0 499  ASP A C     1 ? 
ATOM   3817 O O     . ASP A 1 500 ? -13.228 32.991  -6.935  1.000 24.777  0 499  ASP A O     1 ? 
ATOM   3818 C CB    . ASP A 1 500 ? -14.110 33.605  -3.767  1.000 26.542  0 499  ASP A CB    1 ? 
ATOM   3819 C CG    . ASP A 1 500 ? -14.527 34.770  -2.872  1.000 28.952  0 499  ASP A CG    1 ? 
ATOM   3820 O OD1   . ASP A 1 500 ? -15.092 35.750  -3.420  1.000 29.148  0 499  ASP A OD1   1 ? 
ATOM   3821 O OD2   . ASP A 1 500 ? -14.310 34.670  -1.629  1.000 31.778  0 499  ASP A OD2   1 ? 
ATOM   3822 N N     . LEU A 1 501 ? -14.416 31.340  -5.966  1.000 22.296  0 500  LEU A N     1 ? 
ATOM   3823 C CA    . LEU A 1 501 ? -13.782 30.315  -6.768  1.000 20.295  0 500  LEU A CA    1 ? 
ATOM   3824 C C     . LEU A 1 501 ? -14.189 30.457  -8.231  1.000 21.305  0 500  LEU A C     1 ? 
ATOM   3825 O O     . LEU A 1 501 ? -13.392 30.145  -9.112  1.000 21.241  0 500  LEU A O     1 ? 
ATOM   3826 C CB    . LEU A 1 501 ? -14.109 28.926  -6.223  1.000 19.806  0 500  LEU A CB    1 ? 
ATOM   3827 C CG    . LEU A 1 501 ? -13.324 28.512  -4.980  1.000 20.872  0 500  LEU A CG    1 ? 
ATOM   3828 C CD1   . LEU A 1 501 ? -13.843 27.215  -4.423  1.000 22.359  0 500  LEU A CD1   1 ? 
ATOM   3829 C CD2   . LEU A 1 501 ? -11.818 28.401  -5.250  1.000 24.337  0 500  LEU A CD2   1 ? 
ATOM   3830 N N     . LEU A 1 502 ? -15.436 30.862  -8.489  1.000 20.839  0 501  LEU A N     1 ? 
ATOM   3831 C CA    . LEU A 1 502 ? -15.903 31.028  -9.854  1.000 20.986  0 501  LEU A CA    1 ? 
ATOM   3832 C C     . LEU A 1 502 ? -15.116 32.155  -10.506 1.000 21.420  0 501  LEU A C     1 ? 
ATOM   3833 O O     . LEU A 1 502 ? -14.682 32.037  -11.646 1.000 21.500  0 501  LEU A O     1 ? 
ATOM   3834 C CB    . LEU A 1 502 ? -17.412 31.271  -9.922  1.000 23.256  0 501  LEU A CB    1 ? 
ATOM   3835 C CG    . LEU A 1 502 ? -17.972 31.713  -11.280 1.000 23.877  0 501  LEU A CG    1 ? 
ATOM   3836 C CD1   . LEU A 1 502 ? -17.764 30.647  -12.355 1.000 23.680  0 501  LEU A CD1   1 ? 
ATOM   3837 C CD2   . LEU A 1 502 ? -19.452 32.074  -11.093 1.000 29.494  0 501  LEU A CD2   1 ? 
ATOM   3838 N N     . ALA A 1 503 ? -14.955 33.265  -9.788  1.000 20.393  0 502  ALA A N     1 ? 
ATOM   3839 C CA    . ALA A 1 503 ? -14.233 34.411  -10.315 1.000 21.871  0 502  ALA A CA    1 ? 
ATOM   3840 C C     . ALA A 1 503 ? -12.787 34.001  -10.616 1.000 20.757  0 502  ALA A C     1 ? 
ATOM   3841 O O     . ALA A 1 503 ? -12.247 34.378  -11.654 1.000 21.843  0 502  ALA A O     1 ? 
ATOM   3842 C CB    . ALA A 1 503 ? -14.323 35.597  -9.343  1.000 22.635  0 502  ALA A CB    1 ? 
ATOM   3843 N N     . ALA A 1 504 ? -12.190 33.173  -9.752  1.000 20.592  0 503  ALA A N     1 ? 
ATOM   3844 C CA    . ALA A 1 504 ? -10.842 32.662  -9.989  1.000 20.678  0 503  ALA A CA    1 ? 
ATOM   3845 C C     . ALA A 1 504 ? -10.824 31.689  -11.184 1.000 20.825  0 503  ALA A C     1 ? 
ATOM   3846 O O     . ALA A 1 504 ? -9.945  31.788  -12.031 1.000 22.277  0 503  ALA A O     1 ? 
ATOM   3847 C CB    . ALA A 1 504 ? -10.299 31.997  -8.744  1.000 23.311  0 503  ALA A CB    1 ? 
ATOM   3848 N N     . ALA A 1 505 ? -11.841 30.825  -11.302 1.000 21.342  0 504  ALA A N     1 ? 
ATOM   3849 C CA    . ALA A 1 505 ? -11.935 29.867  -12.398 1.000 18.448  0 504  ALA A CA    1 ? 
ATOM   3850 C C     . ALA A 1 505 ? -12.016 30.589  -13.739 1.000 17.855  0 504  ALA A C     1 ? 
ATOM   3851 O O     . ALA A 1 505 ? -11.442 30.131  -14.754 1.000 19.087  0 504  ALA A O     1 ? 
ATOM   3852 C CB    . ALA A 1 505 ? -13.126 28.952  -12.190 1.000 19.965  0 504  ALA A CB    1 ? 
ATOM   3853 N N     . ARG A 1 506 ? -12.692 31.739  -13.780 1.000 17.611  0 505  ARG A N     1 ? 
ATOM   3854 C CA    . ARG A 1 506 ? -12.783 32.481  -15.043 1.000 18.079  0 505  ARG A CA    1 ? 
ATOM   3855 C C     . ARG A 1 506 ? -11.402 32.958  -15.511 1.000 19.640  0 505  ARG A C     1 ? 
ATOM   3856 O O     . ARG A 1 506 ? -11.208 33.206  -16.709 1.000 21.428  0 505  ARG A O     1 ? 
ATOM   3857 C CB    . ARG A 1 506 ? -13.778 33.645  -14.981 1.000 20.323  0 505  ARG A CB    1 ? 
ATOM   3858 C CG    . ARG A 1 506 ? -15.208 33.281  -14.624 1.000 21.852  0 505  ARG A CG    1 ? 
ATOM   3859 C CD    . ARG A 1 506 ? -16.090 34.491  -14.749 1.000 24.548  0 505  ARG A CD    1 ? 
ATOM   3860 N NE    . ARG A 1 506 ? -17.439 34.279  -14.204 1.000 26.163  0 505  ARG A NE    1 ? 
ATOM   3861 C CZ    . ARG A 1 506 ? -18.467 33.729  -14.823 1.000 28.082  0 505  ARG A CZ    1 ? 
ATOM   3862 N NH1   . ARG A 1 506 ? -18.371 33.136  -15.994 1.000 28.393  0 505  ARG A NH1   1 ? 
ATOM   3863 N NH2   . ARG A 1 506 ? -19.642 33.747  -14.240 1.000 30.411  0 505  ARG A NH2   1 ? 
ATOM   3864 N N     . GLN A 1 507 ? -10.444 33.100  -14.578 1.000 19.074  0 506  GLN A N     1 ? 
ATOM   3865 C CA    . GLN A 1 507 ? -9.085  33.540  -14.883 1.000 18.800  0 506  GLN A CA    1 ? 
ATOM   3866 C C     . GLN A 1 507 ? -8.103  32.381  -15.044 1.000 20.812  0 506  GLN A C     1 ? 
ATOM   3867 O O     . GLN A 1 507 ? -7.110  32.533  -15.731 1.000 21.001  0 506  GLN A O     1 ? 
ATOM   3868 C CB    . GLN A 1 507 ? -8.567  34.414  -13.741 1.000 21.034  0 506  GLN A CB    1 ? 
ATOM   3869 C CG    . GLN A 1 507 ? -9.219  35.786  -13.675 1.000 24.036  0 506  GLN A CG    1 ? 
ATOM   3870 C CD    . GLN A 1 507 ? -8.768  36.614  -14.851 1.000 30.457  0 506  GLN A CD    1 ? 
ATOM   3871 O OE1   . GLN A 1 507 ? -7.593  36.578  -15.236 1.000 32.260  0 506  GLN A OE1   1 ? 
ATOM   3872 N NE2   . GLN A 1 507 ? -9.692  37.307  -15.484 1.000 34.962  0 506  GLN A NE2   1 ? 
ATOM   3873 N N     . ALA A 1 508 ? -8.315  31.258  -14.344 1.000 21.493  0 507  ALA A N     1 ? 
ATOM   3874 C CA    . ALA A 1 508 ? -7.353  30.167  -14.348 1.000 20.726  0 507  ALA A CA    1 ? 
ATOM   3875 C C     . ALA A 1 508 ? -7.681  29.104  -15.401 1.000 20.454  0 507  ALA A C     1 ? 
ATOM   3876 O O     . ALA A 1 508 ? -6.805  28.310  -15.741 1.000 19.470  0 507  ALA A O     1 ? 
ATOM   3877 C CB    . ALA A 1 508 ? -7.289  29.521  -12.985 1.000 21.752  0 507  ALA A CB    1 ? 
ATOM   3878 N N     . THR A 1 509 ? -8.925  29.051  -15.905 1.000 16.262  0 508  THR A N     1 ? 
ATOM   3879 C CA    . THR A 1 509 ? -9.310  27.934  -16.764 1.000 17.161  0 508  THR A CA    1 ? 
ATOM   3880 C C     . THR A 1 509 ? -8.778  28.120  -18.193 1.000 16.608  0 508  THR A C     1 ? 
ATOM   3881 O O     . THR A 1 509 ? -8.857  29.207  -18.779 1.000 17.648  0 508  THR A O     1 ? 
ATOM   3882 C CB    . THR A 1 509 ? -10.841 27.823  -16.757 1.000 17.290  0 508  THR A CB    1 ? 
ATOM   3883 O OG1   . THR A 1 509 ? -11.232 27.356  -15.466 1.000 19.083  0 508  THR A OG1   1 ? 
ATOM   3884 C CG2   . THR A 1 509 ? -11.352 26.789  -17.733 1.000 17.972  0 508  THR A CG2   1 ? 
ATOM   3885 N N     . VAL A 1 510 ? -8.333  27.031  -18.793 1.000 17.332  0 509  VAL A N     1 ? 
ATOM   3886 C CA    . VAL A 1 510 ? -7.919  27.015  -20.193 1.000 18.472  0 509  VAL A CA    1 ? 
ATOM   3887 C C     . VAL A 1 510 ? -8.531  25.766  -20.838 1.000 20.838  0 509  VAL A C     1 ? 
ATOM   3888 O O     . VAL A 1 510 ? -9.266  25.000  -20.193 1.000 21.105  0 509  VAL A O     1 ? 
ATOM   3889 C CB    . VAL A 1 510 ? -6.384  27.083  -20.403 1.000 20.584  0 509  VAL A CB    1 ? 
ATOM   3890 C CG1   . VAL A 1 510 ? -5.804  28.444  -19.991 1.000 21.901  0 509  VAL A CG1   1 ? 
ATOM   3891 C CG2   . VAL A 1 510 ? -5.612  25.994  -19.662 1.000 21.547  0 509  VAL A CG2   1 ? 
ATOM   3892 N N     . THR A 1 511 ? -8.214  25.562  -22.122 1.000 22.458  0 510  THR A N     1 ? 
ATOM   3893 C CA    . THR A 1 511 ? -8.559  24.319  -22.793 1.000 21.627  0 510  THR A CA    1 ? 
ATOM   3894 C C     . THR A 1 511 ? -7.373  23.382  -22.655 1.000 21.769  0 510  THR A C     1 ? 
ATOM   3895 O O     . THR A 1 511 ? -6.209  23.799  -22.768 1.000 23.564  0 510  THR A O     1 ? 
ATOM   3896 C CB    . THR A 1 511 ? -8.940  24.533  -24.262 1.000 23.144  0 510  THR A CB    1 ? 
ATOM   3897 O OG1   . THR A 1 511 ? -8.866  23.229  -24.841 1.000 24.207  0 510  THR A OG1   1 ? 
ATOM   3898 C CG2   . THR A 1 511 ? -8.066  25.533  -25.007 1.000 24.163  0 510  THR A CG2   1 ? 
ATOM   3899 N N     . ILE A 1 512 ? -7.715  22.103  -22.517 1.000 20.475  0 511  ILE A N     1 ? 
ATOM   3900 C CA    . ILE A 1 512 ? -6.749  21.030  -22.469 1.000 20.716  0 511  ILE A CA    1 ? 
ATOM   3901 C C     . ILE A 1 512 ? -6.329  20.654  -23.893 1.000 18.626  0 511  ILE A C     1 ? 
ATOM   3902 O O     . ILE A 1 512 ? -5.437  19.838  -24.069 1.000 22.875  0 511  ILE A O     1 ? 
ATOM   3903 C CB    . ILE A 1 512 ? -7.403  19.862  -21.701 1.000 25.394  0 511  ILE A CB    1 ? 
ATOM   3904 C CG1   . ILE A 1 512 ? -6.415  19.049  -20.977 1.000 26.776  0 511  ILE A CG1   1 ? 
ATOM   3905 C CG2   . ILE A 1 512 ? -8.288  18.991  -22.598 1.000 22.888  0 511  ILE A CG2   1 ? 
ATOM   3906 C CD1   . ILE A 1 512 ? -7.096  18.022  -20.088 1.000 25.938  0 511  ILE A CD1   1 ? 
ATOM   3907 N N     . TRP A 1 513 ? -6.999  21.214  -24.905 1.000 19.087  0 512  TRP A N     1 ? 
ATOM   3908 C CA    . TRP A 1 513 ? -6.718  20.924  -26.310 1.000 21.075  0 512  TRP A CA    1 ? 
ATOM   3909 C C     . TRP A 1 513 ? -7.184  19.523  -26.749 1.000 20.769  0 512  TRP A C     1 ? 
ATOM   3910 O O     . TRP A 1 513 ? -6.445  18.788  -27.393 1.000 19.004  0 512  TRP A O     1 ? 
ATOM   3911 C CB    . TRP A 1 513 ? -5.220  21.119  -26.592 1.000 22.827  0 512  TRP A CB    1 ? 
ATOM   3912 C CG    . TRP A 1 513 ? -4.699  22.475  -26.191 1.000 21.491  0 512  TRP A CG    1 ? 
ATOM   3913 C CD1   . TRP A 1 513 ? -5.268  23.687  -26.422 1.000 21.802  0 512  TRP A CD1   1 ? 
ATOM   3914 C CD2   . TRP A 1 513 ? -3.486  22.742  -25.455 1.000 22.726  0 512  TRP A CD2   1 ? 
ATOM   3915 N NE1   . TRP A 1 513 ? -4.482  24.693  -25.930 1.000 22.805  0 512  TRP A NE1   1 ? 
ATOM   3916 C CE2   . TRP A 1 513 ? -3.385  24.149  -25.321 1.000 21.731  0 512  TRP A CE2   1 ? 
ATOM   3917 C CE3   . TRP A 1 513 ? -2.509  21.934  -24.879 1.000 23.511  0 512  TRP A CE3   1 ? 
ATOM   3918 C CZ2   . TRP A 1 513 ? -2.327  24.765  -24.658 1.000 24.211  0 512  TRP A CZ2   1 ? 
ATOM   3919 C CZ3   . TRP A 1 513 ? -1.473  22.542  -24.186 1.000 27.207  0 512  TRP A CZ3   1 ? 
ATOM   3920 C CH2   . TRP A 1 513 ? -1.392  23.938  -24.073 1.000 27.725  0 512  TRP A CH2   1 ? 
ATOM   3921 N N     . HIS A 1 514 ? -8.450  19.203  -26.456 1.000 18.976  0 513  HIS A N     1 ? 
ATOM   3922 C CA    . HIS A 1 514 ? -9.128  18.001  -26.915 1.000 17.429  0 513  HIS A CA    1 ? 
ATOM   3923 C C     . HIS A 1 514 ? -10.340 18.405  -27.746 1.000 18.071  0 513  HIS A C     1 ? 
ATOM   3924 O O     . HIS A 1 514 ? -11.440 17.903  -27.528 1.000 18.323  0 513  HIS A O     1 ? 
ATOM   3925 C CB    . HIS A 1 514 ? -9.572  17.143  -25.720 1.000 16.804  0 513  HIS A CB    1 ? 
ATOM   3926 C CG    . HIS A 1 514 ? -8.499  16.667  -24.851 1.000 17.490  0 513  HIS A CG    1 ? 
ATOM   3927 N ND1   . HIS A 1 514 ? -8.816  16.098  -23.637 1.000 17.760  0 513  HIS A ND1   1 ? 
ATOM   3928 C CD2   . HIS A 1 514 ? -7.146  16.678  -24.935 1.000 17.264  0 513  HIS A CD2   1 ? 
ATOM   3929 C CE1   . HIS A 1 514 ? -7.691  15.763  -23.016 1.000 19.294  0 513  HIS A CE1   1 ? 
ATOM   3930 N NE2   . HIS A 1 514 ? -6.674  16.123  -23.754 1.000 18.544  0 513  HIS A NE2   1 ? 
ATOM   3931 N N     . PRO A 1 515 ? -10.182 19.274  -28.778 1.000 19.032  0 514  PRO A N     1 ? 
ATOM   3932 C CA    . PRO A 1 515 ? -11.325 19.647  -29.604 1.000 18.998  0 514  PRO A CA    1 ? 
ATOM   3933 C C     . PRO A 1 515 ? -11.872 18.378  -30.285 1.000 19.170  0 514  PRO A C     1 ? 
ATOM   3934 O O     . PRO A 1 515 ? -11.109 17.548  -30.756 1.000 19.718  0 514  PRO A O     1 ? 
ATOM   3935 C CB    . PRO A 1 515 ? -10.780 20.655  -30.596 1.000 20.962  0 514  PRO A CB    1 ? 
ATOM   3936 C CG    . PRO A 1 515 ? -9.276  20.339  -30.643 1.000 20.096  0 514  PRO A CG    1 ? 
ATOM   3937 C CD    . PRO A 1 515 ? -8.913  19.856  -29.234 1.000 19.614  0 514  PRO A CD    1 ? 
ATOM   3938 N N     . MET A 1 516 ? -13.194 18.275  -30.371 1.000 18.314  0 515  MET A N     1 ? 
ATOM   3939 C CA    . MET A 1 516 ? -13.845 17.046  -30.797 1.000 18.928  0 515  MET A CA    1 ? 
ATOM   3940 C C     . MET A 1 516 ? -15.224 17.343  -31.380 1.000 17.009  0 515  MET A C     1 ? 
ATOM   3941 O O     . MET A 1 516 ? -15.819 18.382  -31.064 1.000 15.666  0 515  MET A O     1 ? 
ATOM   3942 C CB    . MET A 1 516 ? -14.015 16.152  -29.556 1.000 18.149  0 515  MET A CB    1 ? 
ATOM   3943 C CG    . MET A 1 516 ? -13.859 14.702  -29.827 1.000 17.994  0 515  MET A CG    1 ? 
ATOM   3944 S SD    . MET A 1 516 ? -12.201 14.208  -30.350 1.000 20.176  0 515  MET A SD    1 ? 
ATOM   3945 C CE    . MET A 1 516 ? -11.265 14.732  -28.916 1.000 21.097  0 515  MET A CE    1 ? 
ATOM   3946 N N     . CYS A 1 517 ? -15.679 16.466  -32.299 1.000 17.480  0 516  CYS A N     1 ? 
ATOM   3947 C CA    . CYS A 1 517 ? -17.091 16.289  -32.663 1.000 18.371  0 516  CYS A CA    1 ? 
ATOM   3948 C C     . CYS A 1 517 ? -17.596 17.279  -33.716 1.000 17.940  0 516  CYS A C     1 ? 
ATOM   3949 O O     . CYS A 1 517 ? -18.811 17.431  -33.845 1.000 18.979  0 516  CYS A O     1 ? 
ATOM   3950 C CB    . CYS A 1 517 ? -18.043 16.418  -31.481 1.000 18.984  0 516  CYS A CB    1 ? 
ATOM   3951 S SG    . CYS A 1 517 ? -17.585 15.404  -30.047 1.000 20.175  0 516  CYS A SG    1 ? 
ATOM   3952 N N     . THR A 1 518 ? -16.685 17.902  -34.474 1.000 18.352  0 517  THR A N     1 ? 
ATOM   3953 C CA    . THR A 1 518 ? -17.005 18.928  -35.454 1.000 18.466  0 517  THR A CA    1 ? 
ATOM   3954 C C     . THR A 1 518 ? -17.428 18.387  -36.824 1.000 19.257  0 517  THR A C     1 ? 
ATOM   3955 O O     . THR A 1 518 ? -17.752 19.181  -37.697 1.000 21.331  0 517  THR A O     1 ? 
ATOM   3956 C CB    . THR A 1 518 ? -15.822 19.876  -35.612 1.000 18.773  0 517  THR A CB    1 ? 
ATOM   3957 O OG1   . THR A 1 518 ? -14.658 19.111  -35.920 1.000 20.333  0 517  THR A OG1   1 ? 
ATOM   3958 C CG2   . THR A 1 518 ? -15.613 20.714  -34.370 1.000 20.286  0 517  THR A CG2   1 ? 
ATOM   3959 N N     . ALA A 1 519 ? -17.382 17.070  -37.051 1.000 17.954  0 518  ALA A N     1 ? 
ATOM   3960 C CA    . ALA A 1 519 ? -18.030 16.488  -38.221 1.000 19.674  0 518  ALA A CA    1 ? 
ATOM   3961 C C     . ALA A 1 519 ? -18.561 15.121  -37.826 1.000 18.257  0 518  ALA A C     1 ? 
ATOM   3962 O O     . ALA A 1 519 ? -18.161 14.106  -38.393 1.000 20.492  0 518  ALA A O     1 ? 
ATOM   3963 C CB    . ALA A 1 519 ? -17.088 16.389  -39.394 1.000 18.598  0 518  ALA A CB    1 ? 
ATOM   3964 N N     . ARG A 1 520 ? -19.448 15.120  -36.829 1.000 19.208  0 519  ARG A N     1 ? 
ATOM   3965 C CA    . ARG A 1 520 ? -19.670 13.944  -36.005 1.000 18.740  0 519  ARG A CA    1 ? 
ATOM   3966 C C     . ARG A 1 520 ? -20.650 12.948  -36.640 1.000 20.799  0 519  ARG A C     1 ? 
ATOM   3967 O O     . ARG A 1 520 ? -21.517 13.322  -37.436 1.000 19.273  0 519  ARG A O     1 ? 
ATOM   3968 C CB    . ARG A 1 520 ? -20.132 14.357  -34.612 1.000 18.585  0 519  ARG A CB    1 ? 
ATOM   3969 C CG    . ARG A 1 520 ? -21.549 14.873  -34.515 1.000 20.004  0 519  ARG A CG    1 ? 
ATOM   3970 C CD    . ARG A 1 520 ? -21.792 15.417  -33.124 1.000 20.582  0 519  ARG A CD    1 ? 
ATOM   3971 N NE    . ARG A 1 520 ? -23.183 15.848  -33.095 1.000 20.784  0 519  ARG A NE    1 ? 
ATOM   3972 C CZ    . ARG A 1 520 ? -23.808 16.317  -32.038 1.000 23.837  0 519  ARG A CZ    1 ? 
ATOM   3973 N NH1   . ARG A 1 520 ? -23.229 16.283  -30.864 1.000 22.782  0 519  ARG A NH1   1 ? 
ATOM   3974 N NH2   . ARG A 1 520 ? -25.034 16.772  -32.171 1.000 23.733  0 519  ARG A NH2   1 ? 
ATOM   3975 N N     . MET A 1 521 ? -20.528 11.675  -36.239 1.000 18.877  0 520  MET A N     1 ? 
ATOM   3976 C CA    . MET A 1 521 ? -21.470 10.643  -36.659 1.000 22.506  0 520  MET A CA    1 ? 
ATOM   3977 C C     . MET A 1 521 ? -22.879 10.911  -36.114 1.000 24.010  0 520  MET A C     1 ? 
ATOM   3978 O O     . MET A 1 521 ? -23.078 11.328  -34.977 1.000 20.347  0 520  MET A O     1 ? 
ATOM   3979 C CB    . MET A 1 521 ? -21.070 9.266   -36.136 1.000 23.624  0 520  MET A CB    1 ? 
ATOM   3980 C CG    . MET A 1 521 ? -19.842 8.693   -36.756 1.000 24.414  0 520  MET A CG    1 ? 
ATOM   3981 S SD    . MET A 1 521 ? -19.683 6.988   -36.166 1.000 23.975  0 520  MET A SD    1 ? 
ATOM   3982 C CE    . MET A 1 521 ? -19.384 7.057   -34.395 1.000 20.535  0 520  MET A CE    1 ? 
ATOM   3983 N N     . ALA A 1 522 ? -23.860 10.661  -36.971 1.000 20.535  0 521  ALA A N     1 ? 
ATOM   3984 C CA    . ALA A 1 522 ? -25.255 10.650  -36.581 1.000 23.529  0 521  ALA A CA    1 ? 
ATOM   3985 C C     . ALA A 1 522 ? -26.016 9.639   -37.441 1.000 24.494  0 521  ALA A C     1 ? 
ATOM   3986 O O     . ALA A 1 522 ? -25.580 9.301   -38.550 1.000 24.223  0 521  ALA A O     1 ? 
ATOM   3987 C CB    . ALA A 1 522 ? -25.819 12.037  -36.713 1.000 23.792  0 521  ALA A CB    1 ? 
ATOM   3988 N N     . PRO A 1 523 ? -27.205 9.173   -36.993 1.000 24.890  0 522  PRO A N     1 ? 
ATOM   3989 C CA    . PRO A 1 523 ? -28.032 8.263   -37.805 1.000 25.166  0 522  PRO A CA    1 ? 
ATOM   3990 C C     . PRO A 1 523 ? -28.327 8.771   -39.217 1.000 24.976  0 522  PRO A C     1 ? 
ATOM   3991 O O     . PRO A 1 523 ? -28.437 9.965   -39.428 1.000 25.253  0 522  PRO A O     1 ? 
ATOM   3992 C CB    . PRO A 1 523 ? -29.322 8.134   -36.972 1.000 25.328  0 522  PRO A CB    1 ? 
ATOM   3993 C CG    . PRO A 1 523 ? -28.889 8.424   -35.564 1.000 26.517  0 522  PRO A CG    1 ? 
ATOM   3994 C CD    . PRO A 1 523 ? -27.814 9.500   -35.698 1.000 24.983  0 522  PRO A CD    1 ? 
ATOM   3995 N N     . LYS A 1 524 ? -28.461 7.865   -40.194 1.000 27.399  0 523  LYS A N     1 ? 
ATOM   3996 C CA    . LYS A 1 524 ? -28.956 8.255   -41.506 1.000 31.199  0 523  LYS A CA    1 ? 
ATOM   3997 C C     . LYS A 1 524 ? -30.253 9.044   -41.328 1.000 30.238  0 523  LYS A C     1 ? 
ATOM   3998 O O     . LYS A 1 524 ? -31.089 8.656   -40.528 1.000 29.065  0 523  LYS A O     1 ? 
ATOM   3999 C CB    . LYS A 1 524 ? -29.176 7.039   -42.413 1.000 36.816  0 523  LYS A CB    1 ? 
ATOM   4000 C CG    . LYS A 1 524 ? -27.947 6.159   -42.551 1.000 49.499  0 523  LYS A CG    1 ? 
ATOM   4001 C CD    . LYS A 1 524 ? -27.803 5.339   -43.832 1.000 57.125  0 523  LYS A CD    1 ? 
ATOM   4002 C CE    . LYS A 1 524 ? -26.463 4.656   -43.821 1.000 62.317  0 523  LYS A CE    1 ? 
ATOM   4003 N NZ    . LYS A 1 524 ? -26.223 3.862   -45.031 1.000 68.032  0 523  LYS A NZ    1 ? 
ATOM   4004 N N     . GLY A 1 525 ? -30.365 10.189  -42.020 1.000 32.766  0 524  GLY A N     1 ? 
ATOM   4005 C CA    . GLY A 1 525 ? -31.572 10.994  -41.994 1.000 33.890  0 524  GLY A CA    1 ? 
ATOM   4006 C C     . GLY A 1 525 ? -31.537 12.076  -40.922 1.000 37.852  0 524  GLY A C     1 ? 
ATOM   4007 O O     . GLY A 1 525 ? -32.405 12.938  -40.903 1.000 38.941  0 524  GLY A O     1 ? 
ATOM   4008 N N     . SER A 1 526 ? -30.559 12.023  -40.007 1.000 35.463  0 525  SER A N     1 ? 
ATOM   4009 C CA    . SER A 1 526 ? -30.423 13.056  -38.998 1.000 31.322  0 525  SER A CA    1 ? 
ATOM   4010 C C     . SER A 1 526 ? -29.457 14.126  -39.504 1.000 34.404  0 525  SER A C     1 ? 
ATOM   4011 O O     . SER A 1 526 ? -28.459 13.788  -40.137 1.000 33.349  0 525  SER A O     1 ? 
ATOM   4012 C CB    . SER A 1 526 ? -29.954 12.460  -37.703 1.000 30.524  0 525  SER A CB    1 ? 
ATOM   4013 O OG    . SER A 1 526 ? -29.738 13.476  -36.736 1.000 30.990  0 525  SER A OG    1 ? 
ATOM   4014 N N     . THR A 1 527 ? -29.725 15.407  -39.198 1.000 29.595  0 526  THR A N     1 ? 
ATOM   4015 C CA    . THR A 1 527 ? -28.744 16.450  -39.479 1.000 32.285  0 526  THR A CA    1 ? 
ATOM   4016 C C     . THR A 1 527 ? -28.004 16.848  -38.196 1.000 30.294  0 526  THR A C     1 ? 
ATOM   4017 O O     . THR A 1 527 ? -27.275 17.831  -38.197 1.000 30.890  0 526  THR A O     1 ? 
ATOM   4018 C CB    . THR A 1 527 ? -29.419 17.640  -40.161 1.000 39.392  0 526  THR A CB    1 ? 
ATOM   4019 O OG1   . THR A 1 527 ? -30.412 18.026  -39.217 1.000 35.637  0 526  THR A OG1   1 ? 
ATOM   4020 C CG2   . THR A 1 527 ? -29.988 17.263  -41.521 1.000 40.878  0 526  THR A CG2   1 ? 
ATOM   4021 N N     . ASP A 1 528 ? -28.121 16.033  -37.139 1.000 26.895  0 527  ASP A N     1 ? 
ATOM   4022 C CA    . ASP A 1 528 ? -27.419 16.272  -35.890 1.000 29.646  0 527  ASP A CA    1 ? 
ATOM   4023 C C     . ASP A 1 528 ? -25.915 16.020  -36.034 1.000 26.516  0 527  ASP A C     1 ? 
ATOM   4024 O O     . ASP A 1 528 ? -25.141 16.390  -35.151 1.000 27.813  0 527  ASP A O     1 ? 
ATOM   4025 C CB    . ASP A 1 528 ? -27.946 15.364  -34.794 1.000 30.861  0 527  ASP A CB    1 ? 
ATOM   4026 C CG    . ASP A 1 528 ? -29.293 15.724  -34.199 1.000 39.484  0 527  ASP A CG    1 ? 
ATOM   4027 O OD1   . ASP A 1 528 ? -29.734 16.863  -34.394 1.000 40.950  0 527  ASP A OD1   1 ? 
ATOM   4028 O OD2   . ASP A 1 528 ? -29.879 14.854  -33.514 1.000 49.979  0 527  ASP A OD2   1 ? 
ATOM   4029 N N     . GLY A 1 529 ? -25.495 15.417  -37.146 1.000 22.592  0 528  GLY A N     1 ? 
ATOM   4030 C CA    . GLY A 1 529 ? -24.084 15.176  -37.394 1.000 22.507  0 528  GLY A CA    1 ? 
ATOM   4031 C C     . GLY A 1 529 ? -23.792 15.299  -38.884 1.000 23.432  0 528  GLY A C     1 ? 
ATOM   4032 O O     . GLY A 1 529 ? -24.717 15.528  -39.669 1.000 22.167  0 528  GLY A O     1 ? 
ATOM   4033 N N     . ALA A 1 530 ? -22.506 15.269  -39.245 1.000 20.243  0 529  ALA A N     1 ? 
ATOM   4034 C CA    . ALA A 1 530 ? -22.117 15.524  -40.623 1.000 20.526  0 529  ALA A CA    1 ? 
ATOM   4035 C C     . ALA A 1 530 ? -21.904 14.233  -41.414 1.000 19.497  0 529  ALA A C     1 ? 
ATOM   4036 O O     . ALA A 1 530 ? -21.810 14.266  -42.658 1.000 20.382  0 529  ALA A O     1 ? 
ATOM   4037 C CB    . ALA A 1 530 ? -20.886 16.374  -40.662 1.000 20.141  0 529  ALA A CB    1 ? 
ATOM   4038 N N     . ILE A 1 531 ? -21.717 13.138  -40.687 1.000 19.079  0 530  ILE A N     1 ? 
ATOM   4039 C CA    . ILE A 1 531 ? -21.373 11.867  -41.299 1.000 20.594  0 530  ILE A CA    1 ? 
ATOM   4040 C C     . ILE A 1 531 ? -22.286 10.770  -40.759 1.000 19.885  0 530  ILE A C     1 ? 
ATOM   4041 O O     . ILE A 1 531 ? -22.802 10.859  -39.655 1.000 21.062  0 530  ILE A O     1 ? 
ATOM   4042 C CB    . ILE A 1 531 ? -19.876 11.549  -41.089 1.000 19.877  0 530  ILE A CB    1 ? 
ATOM   4043 C CG1   . ILE A 1 531 ? -19.556 11.120  -39.659 1.000 18.929  0 530  ILE A CG1   1 ? 
ATOM   4044 C CG2   . ILE A 1 531 ? -18.996 12.711  -41.545 1.000 20.178  0 530  ILE A CG2   1 ? 
ATOM   4045 C CD1   . ILE A 1 531 ? -18.063 10.886  -39.431 1.000 19.732  0 530  ILE A CD1   1 ? 
ATOM   4046 N N     . ASP A 1 532 ? -22.433 9.698   -41.530 1.000 19.591  0 531  ASP A N     1 ? 
ATOM   4047 C CA    . ASP A 1 532 ? -23.241 8.567   -41.146 1.000 21.919  0 531  ASP A CA    1 ? 
ATOM   4048 C C     . ASP A 1 532 ? -22.466 7.665   -40.186 1.000 22.674  0 531  ASP A C     1 ? 
ATOM   4049 O O     . ASP A 1 532 ? -21.276 7.852   -39.955 1.000 20.479  0 531  ASP A O     1 ? 
ATOM   4050 C CB    . ASP A 1 532 ? -23.762 7.834   -42.375 1.000 24.197  0 531  ASP A CB    1 ? 
ATOM   4051 C CG    . ASP A 1 532 ? -24.919 8.525   -43.081 1.000 27.212  0 531  ASP A CG    1 ? 
ATOM   4052 O OD1   . ASP A 1 532 ? -25.649 9.268   -42.419 1.000 25.782  0 531  ASP A OD1   1 ? 
ATOM   4053 O OD2   . ASP A 1 532 ? -25.037 8.367   -44.305 1.000 29.557  0 531  ASP A OD2   1 ? 
ATOM   4054 N N     . PRO A 1 533 ? -23.127 6.656   -39.591 1.000 22.157  0 532  PRO A N     1 ? 
ATOM   4055 C CA    . PRO A 1 533 ? -22.450 5.754   -38.656 1.000 20.739  0 532  PRO A CA    1 ? 
ATOM   4056 C C     . PRO A 1 533 ? -21.326 4.918   -39.246 1.000 20.659  0 532  PRO A C     1 ? 
ATOM   4057 O O     . PRO A 1 533 ? -20.598 4.268   -38.505 1.000 20.939  0 532  PRO A O     1 ? 
ATOM   4058 C CB    . PRO A 1 533 ? -23.607 4.897   -38.177 1.000 21.814  0 532  PRO A CB    1 ? 
ATOM   4059 C CG    . PRO A 1 533 ? -24.816 5.795   -38.310 1.000 21.194  0 532  PRO A CG    1 ? 
ATOM   4060 C CD    . PRO A 1 533 ? -24.587 6.406   -39.660 1.000 22.445  0 532  PRO A CD    1 ? 
ATOM   4061 N N     . ASP A 1 534 ? -21.225 4.901   -40.580 1.000 20.733  0 533  ASP A N     1 ? 
ATOM   4062 C CA    . ASP A 1 534 ? -20.114 4.253   -41.252 1.000 22.610  0 533  ASP A CA    1 ? 
ATOM   4063 C C     . ASP A 1 534 ? -18.973 5.231   -41.563 1.000 20.532  0 533  ASP A C     1 ? 
ATOM   4064 O O     . ASP A 1 534 ? -18.020 4.829   -42.239 1.000 22.410  0 533  ASP A O     1 ? 
ATOM   4065 C CB    . ASP A 1 534 ? -20.584 3.599   -42.549 1.000 23.919  0 533  ASP A CB    1 ? 
ATOM   4066 C CG    . ASP A 1 534 ? -21.369 4.516   -43.478 1.000 26.943  0 533  ASP A CG    1 ? 
ATOM   4067 O OD1   . ASP A 1 534 ? -21.387 5.761   -43.235 1.000 24.592  0 533  ASP A OD1   1 ? 
ATOM   4068 O OD2   . ASP A 1 534 ? -21.946 3.983   -44.478 1.000 30.732  0 533  ASP A OD2   1 ? 
ATOM   4069 N N     . LEU A 1 535 ? -19.087 6.482   -41.086 1.000 19.966  0 534  LEU A N     1 ? 
ATOM   4070 C CA    . LEU A 1 535 ? -18.094 7.553   -41.180 1.000 17.387  0 534  LEU A CA    1 ? 
ATOM   4071 C C     . LEU A 1 535 ? -18.116 8.264   -42.530 1.000 17.197  0 534  LEU A C     1 ? 
ATOM   4072 O O     . LEU A 1 535 ? -17.276 9.140   -42.773 1.000 16.640  0 534  LEU A O     1 ? 
ATOM   4073 C CB    . LEU A 1 535 ? -16.681 7.075   -40.852 1.000 18.116  0 534  LEU A CB    1 ? 
ATOM   4074 C CG    . LEU A 1 535 ? -16.565 6.316   -39.532 1.000 19.976  0 534  LEU A CG    1 ? 
ATOM   4075 C CD1   . LEU A 1 535 ? -15.236 5.631   -39.423 1.000 23.620  0 534  LEU A CD1   1 ? 
ATOM   4076 C CD2   . LEU A 1 535 ? -16.769 7.281   -38.414 1.000 19.863  0 534  LEU A CD2   1 ? 
ATOM   4077 N N     . LEU A 1 536 ? -19.033 7.873   -43.419 1.000 18.030  0 535  LEU A N     1 ? 
ATOM   4078 C CA    . LEU A 1 536 ? -19.111 8.522   -44.716 1.000 19.782  0 535  LEU A CA    1 ? 
ATOM   4079 C C     . LEU A 1 536 ? -19.929 9.814   -44.619 1.000 19.726  0 535  LEU A C     1 ? 
ATOM   4080 O O     . LEU A 1 536 ? -21.012 9.854   -44.034 1.000 20.915  0 535  LEU A O     1 ? 
ATOM   4081 C CB    . LEU A 1 536 ? -19.691 7.557   -45.733 1.000 20.705  0 535  LEU A CB    1 ? 
ATOM   4082 C CG    . LEU A 1 536 ? -18.816 6.347   -46.082 1.000 22.457  0 535  LEU A CG    1 ? 
ATOM   4083 C CD1   . LEU A 1 536 ? -19.682 5.267   -46.748 1.000 22.854  0 535  LEU A CD1   1 ? 
ATOM   4084 C CD2   . LEU A 1 536 ? -17.672 6.800   -46.962 1.000 24.716  0 535  LEU A CD2   1 ? 
ATOM   4085 N N     . VAL A 1 537 ? -19.398 10.867  -45.251 1.000 20.762  0 536  VAL A N     1 ? 
ATOM   4086 C CA    . VAL A 1 537 ? -20.009 12.182  -45.202 1.000 20.993  0 536  VAL A CA    1 ? 
ATOM   4087 C C     . VAL A 1 537 ? -21.412 12.128  -45.819 1.000 22.145  0 536  VAL A C     1 ? 
ATOM   4088 O O     . VAL A 1 537 ? -21.605 11.577  -46.897 1.000 21.763  0 536  VAL A O     1 ? 
ATOM   4089 C CB    . VAL A 1 537 ? -19.118 13.220  -45.905 1.000 20.345  0 536  VAL A CB    1 ? 
ATOM   4090 C CG1   . VAL A 1 537 ? -19.773 14.601  -45.972 1.000 22.750  0 536  VAL A CG1   1 ? 
ATOM   4091 C CG2   . VAL A 1 537 ? -17.739 13.306  -45.276 1.000 20.024  0 536  VAL A CG2   1 ? 
ATOM   4092 N N     . LYS A 1 538 ? -22.352 12.791  -45.145 1.000 19.521  0 537  LYS A N     1 ? 
ATOM   4093 C CA    . LYS A 1 538 ? -23.735 12.849  -45.584 1.000 22.382  0 537  LYS A CA    1 ? 
ATOM   4094 C C     . LYS A 1 538 ? -23.844 13.715  -46.825 1.000 23.372  0 537  LYS A C     1 ? 
ATOM   4095 O O     . LYS A 1 538 ? -23.224 14.763  -46.891 1.000 23.536  0 537  LYS A O     1 ? 
ATOM   4096 C CB    . LYS A 1 538 ? -24.649 13.437  -44.524 1.000 21.622  0 537  LYS A CB    1 ? 
ATOM   4097 C CG    . LYS A 1 538 ? -24.848 12.519  -43.308 1.000 21.594  0 537  LYS A CG    1 ? 
ATOM   4098 C CD    . LYS A 1 538 ? -25.472 13.320  -42.177 1.000 22.234  0 537  LYS A CD    1 ? 
ATOM   4099 C CE    . LYS A 1 538 ? -25.579 12.506  -40.917 1.000 22.695  0 537  LYS A CE    1 ? 
ATOM   4100 N NZ    . LYS A 1 538 ? -26.567 11.441  -41.095 1.000 23.225  0 537  LYS A NZ    1 ? 
ATOM   4101 N N     . GLY A 1 539 ? -24.533 13.178  -47.840 1.000 26.442  0 538  GLY A N     1 ? 
ATOM   4102 C CA    . GLY A 1 539 ? -24.787 13.927  -49.061 1.000 27.463  0 538  GLY A CA    1 ? 
ATOM   4103 C C     . GLY A 1 539 ? -23.707 13.752  -50.119 1.000 25.261  0 538  GLY A C     1 ? 
ATOM   4104 O O     . GLY A 1 539 ? -23.836 14.340  -51.194 1.000 26.761  0 538  GLY A O     1 ? 
ATOM   4105 N N     . VAL A 1 540 ? -22.681 12.938  -49.830 1.000 25.230  0 539  VAL A N     1 ? 
ATOM   4106 C CA    . VAL A 1 540 ? -21.499 12.785  -50.660 1.000 25.102  0 539  VAL A CA    1 ? 
ATOM   4107 C C     . VAL A 1 540 ? -21.200 11.296  -50.865 1.000 25.236  0 539  VAL A C     1 ? 
ATOM   4108 O O     . VAL A 1 540 ? -21.431 10.468  -49.995 1.000 25.859  0 539  VAL A O     1 ? 
ATOM   4109 C CB    . VAL A 1 540 ? -20.319 13.505  -49.981 1.000 24.484  0 539  VAL A CB    1 ? 
ATOM   4110 C CG1   . VAL A 1 540 ? -19.014 13.344  -50.733 1.000 23.005  0 539  VAL A CG1   1 ? 
ATOM   4111 C CG2   . VAL A 1 540 ? -20.592 14.982  -49.747 1.000 23.753  0 539  VAL A CG2   1 ? 
ATOM   4112 N N     . SER A 1 541 ? -20.675 10.954  -52.033 1.000 23.988  0 540  SER A N     1 ? 
ATOM   4113 C CA    . SER A 1 541 ? -20.141 9.624   -52.271 1.000 24.561  0 540  SER A CA    1 ? 
ATOM   4114 C C     . SER A 1 541 ? -18.602 9.664   -52.243 1.000 21.210  0 540  SER A C     1 ? 
ATOM   4115 O O     . SER A 1 541 ? -17.987 10.576  -52.787 1.000 24.685  0 540  SER A O     1 ? 
ATOM   4116 C CB    . SER A 1 541 ? -20.703 9.100   -53.587 1.000 28.494  0 540  SER A CB    1 ? 
ATOM   4117 O OG    . SER A 1 541 ? -19.883 8.043   -54.085 1.000 35.647  0 540  SER A OG    1 ? 
ATOM   4118 N N     . GLY A 1 542 ? -17.962 8.674   -51.599 1.000 21.095  0 541  GLY A N     1 ? 
ATOM   4119 C CA    . GLY A 1 542 ? -16.512 8.500   -51.703 1.000 22.721  0 541  GLY A CA    1 ? 
ATOM   4120 C C     . GLY A 1 542 ? -15.675 9.328   -50.715 1.000 21.544  0 541  GLY A C     1 ? 
ATOM   4121 O O     . GLY A 1 542 ? -14.459 9.439   -50.892 1.000 23.372  0 541  GLY A O     1 ? 
ATOM   4122 N N     . LEU A 1 543 ? -16.290 9.864   -49.658 1.000 20.784  0 542  LEU A N     1 ? 
ATOM   4123 C CA    . LEU A 1 543 ? -15.595 10.733  -48.723 1.000 19.798  0 542  LEU A CA    1 ? 
ATOM   4124 C C     . LEU A 1 543 ? -15.886 10.279  -47.301 1.000 17.752  0 542  LEU A C     1 ? 
ATOM   4125 O O     . LEU A 1 543 ? -17.031 10.218  -46.894 1.000 18.957  0 542  LEU A O     1 ? 
ATOM   4126 C CB    . LEU A 1 543 ? -16.090 12.162  -48.920 1.000 18.671  0 542  LEU A CB    1 ? 
ATOM   4127 C CG    . LEU A 1 543 ? -15.390 13.249  -48.096 1.000 19.475  0 542  LEU A CG    1 ? 
ATOM   4128 C CD1   . LEU A 1 543 ? -13.879 13.237  -48.269 1.000 19.935  0 542  LEU A CD1   1 ? 
ATOM   4129 C CD2   . LEU A 1 543 ? -15.922 14.624  -48.421 1.000 18.542  0 542  LEU A CD2   1 ? 
ATOM   4130 N N     . ARG A 1 544 ? -14.849 9.996   -46.549 1.000 18.612  0 543  ARG A N     1 ? 
ATOM   4131 C CA    . ARG A 1 544 ? -15.013 9.446   -45.210 1.000 19.622  0 543  ARG A CA    1 ? 
ATOM   4132 C C     . ARG A 1 544 ? -14.196 10.320  -44.264 1.000 19.189  0 543  ARG A C     1 ? 
ATOM   4133 O O     . ARG A 1 544 ? -13.197 10.908  -44.665 1.000 19.981  0 543  ARG A O     1 ? 
ATOM   4134 C CB    . ARG A 1 544 ? -14.560 7.979   -45.250 1.000 22.033  0 543  ARG A CB    1 ? 
ATOM   4135 C CG    . ARG A 1 544 ? -15.066 7.099   -44.119 1.000 23.001  0 543  ARG A CG    1 ? 
ATOM   4136 C CD    . ARG A 1 544 ? -14.563 5.670   -44.235 1.000 23.752  0 543  ARG A CD    1 ? 
ATOM   4137 N NE    . ARG A 1 544 ? -15.093 4.979   -45.423 1.000 22.591  0 543  ARG A NE    1 ? 
ATOM   4138 C CZ    . ARG A 1 544 ? -15.934 3.941   -45.362 1.000 22.613  0 543  ARG A CZ    1 ? 
ATOM   4139 N NH1   . ARG A 1 544 ? -16.540 3.587   -44.239 1.000 20.667  0 543  ARG A NH1   1 ? 
ATOM   4140 N NH2   . ARG A 1 544 ? -16.149 3.219   -46.436 1.000 21.477  0 543  ARG A NH2   1 ? 
ATOM   4141 N N     . VAL A 1 545 ? -14.652 10.446  -43.015 1.000 18.721  0 544  VAL A N     1 ? 
ATOM   4142 C CA    . VAL A 1 545 ? -13.975 11.235  -42.014 1.000 19.091  0 544  VAL A CA    1 ? 
ATOM   4143 C C     . VAL A 1 545 ? -13.573 10.266  -40.901 1.000 16.585  0 544  VAL A C     1 ? 
ATOM   4144 O O     . VAL A 1 545 ? -14.431 9.619   -40.315 1.000 18.379  0 544  VAL A O     1 ? 
ATOM   4145 C CB    . VAL A 1 545 ? -14.866 12.354  -41.450 1.000 18.824  0 544  VAL A CB    1 ? 
ATOM   4146 C CG1   . VAL A 1 545 ? -14.259 12.983  -40.199 1.000 19.060  0 544  VAL A CG1   1 ? 
ATOM   4147 C CG2   . VAL A 1 545 ? -15.178 13.416  -42.484 1.000 19.673  0 544  VAL A CG2   1 ? 
ATOM   4148 N N     . ILE A 1 546 ? -12.274 10.157  -40.663 1.000 17.529  0 545  ILE A N     1 ? 
ATOM   4149 C CA    . ILE A 1 546 ? -11.758 9.326   -39.594 1.000 18.428  0 545  ILE A CA    1 ? 
ATOM   4150 C C     . ILE A 1 546 ? -10.741 10.138  -38.786 1.000 18.975  0 545  ILE A C     1 ? 
ATOM   4151 O O     . ILE A 1 546 ? -9.563  10.200  -39.131 1.000 18.544  0 545  ILE A O     1 ? 
ATOM   4152 C CB    . ILE A 1 546 ? -11.145 8.039   -40.167 1.000 18.974  0 545  ILE A CB    1 ? 
ATOM   4153 C CG1   . ILE A 1 546 ? -12.106 7.306   -41.055 1.000 20.493  0 545  ILE A CG1   1 ? 
ATOM   4154 C CG2   . ILE A 1 546 ? -10.689 7.158   -38.999 1.000 19.791  0 545  ILE A CG2   1 ? 
ATOM   4155 C CD1   . ILE A 1 546 ? -11.557 5.987   -41.586 1.000 21.046  0 545  ILE A CD1   1 ? 
ATOM   4156 N N     . ASP A 1 547 ? -11.199 10.666  -37.646 1.000 19.924  0 546  ASP A N     1 ? 
ATOM   4157 C CA    . ASP A 1 547 ? -10.392 11.495  -36.760 1.000 17.899  0 546  ASP A CA    1 ? 
ATOM   4158 C C     . ASP A 1 547 ? -11.322 11.950  -35.642 1.000 17.851  0 546  ASP A C     1 ? 
ATOM   4159 O O     . ASP A 1 547 ? -12.490 11.505  -35.572 1.000 15.775  0 546  ASP A O     1 ? 
ATOM   4160 C CB    . ASP A 1 547 ? -9.677  12.613  -37.500 1.000 18.795  0 546  ASP A CB    1 ? 
ATOM   4161 C CG    . ASP A 1 547 ? -10.582 13.656  -38.154 1.000 20.195  0 546  ASP A CG    1 ? 
ATOM   4162 O OD1   . ASP A 1 547 ? -11.777 13.744  -37.797 1.000 20.634  0 546  ASP A OD1   1 ? 
ATOM   4163 O OD2   . ASP A 1 547 ? -10.110 14.348  -39.066 1.000 21.951  0 546  ASP A OD2   1 ? 
ATOM   4164 N N     . GLY A 1 548 ? -10.802 12.847  -34.808 1.000 17.263  0 547  GLY A N     1 ? 
ATOM   4165 C CA    . GLY A 1 548 ? -11.545 13.402  -33.688 1.000 19.393  0 547  GLY A CA    1 ? 
ATOM   4166 C C     . GLY A 1 548 ? -12.851 14.087  -34.073 1.000 17.846  0 547  GLY A C     1 ? 
ATOM   4167 O O     . GLY A 1 548 ? -13.762 14.159  -33.249 1.000 17.768  0 547  GLY A O     1 ? 
ATOM   4168 N N     . ALA A 1 549 ? -12.954 14.568  -35.327 1.000 17.113  0 548  ALA A N     1 ? 
ATOM   4169 C CA    . ALA A 1 549 ? -14.176 15.231  -35.786 1.000 16.963  0 548  ALA A CA    1 ? 
ATOM   4170 C C     . ALA A 1 549 ? -15.378 14.292  -35.813 1.000 18.693  0 548  ALA A C     1 ? 
ATOM   4171 O O     . ALA A 1 549 ? -16.518 14.743  -35.603 1.000 19.805  0 548  ALA A O     1 ? 
ATOM   4172 C CB    . ALA A 1 549 ? -13.946 15.820  -37.161 1.000 17.775  0 548  ALA A CB    1 ? 
ATOM   4173 N N     . ALA A 1 550 ? -15.116 12.996  -35.993 1.000 19.342  0 549  ALA A N     1 ? 
ATOM   4174 C CA    . ALA A 1 550 ? -16.153 11.981  -36.156 1.000 20.076  0 549  ALA A CA    1 ? 
ATOM   4175 C C     . ALA A 1 550 ? -16.848 11.566  -34.873 1.000 20.492  0 549  ALA A C     1 ? 
ATOM   4176 O O     . ALA A 1 550 ? -17.968 11.046  -34.945 1.000 20.313  0 549  ALA A O     1 ? 
ATOM   4177 C CB    . ALA A 1 550 ? -15.604 10.729  -36.825 1.000 20.795  0 549  ALA A CB    1 ? 
ATOM   4178 N N     . LEU A 1 551 ? -16.202 11.722  -33.711 1.000 19.527  0 550  LEU A N     1 ? 
ATOM   4179 C CA    . LEU A 1 551 ? -16.789 11.178  -32.500 1.000 19.547  0 550  LEU A CA    1 ? 
ATOM   4180 C C     . LEU A 1 551 ? -18.099 11.913  -32.201 1.000 18.834  0 550  LEU A C     1 ? 
ATOM   4181 O O     . LEU A 1 551 ? -18.151 13.144  -32.295 1.000 17.855  0 550  LEU A O     1 ? 
ATOM   4182 C CB    . LEU A 1 551 ? -15.819 11.311  -31.331 1.000 19.009  0 550  LEU A CB    1 ? 
ATOM   4183 C CG    . LEU A 1 551 ? -14.698 10.260  -31.276 1.000 22.779  0 550  LEU A CG    1 ? 
ATOM   4184 C CD1   . LEU A 1 551 ? -13.761 10.299  -32.434 1.000 25.573  0 550  LEU A CD1   1 ? 
ATOM   4185 C CD2   . LEU A 1 551 ? -13.919 10.442  -29.967 1.000 23.758  0 550  LEU A CD2   1 ? 
ATOM   4186 N N     . PRO A 1 552 ? -19.181 11.193  -31.847 1.000 19.500  0 551  PRO A N     1 ? 
ATOM   4187 C CA    . PRO A 1 552 ? -20.484 11.828  -31.575 1.000 18.079  0 551  PRO A CA    1 ? 
ATOM   4188 C C     . PRO A 1 552 ? -20.634 12.492  -30.202 1.000 20.304  0 551  PRO A C     1 ? 
ATOM   4189 O O     . PRO A 1 552 ? -21.606 13.196  -29.952 1.000 21.965  0 551  PRO A O     1 ? 
ATOM   4190 C CB    . PRO A 1 552 ? -21.467 10.668  -31.730 1.000 19.543  0 551  PRO A CB    1 ? 
ATOM   4191 C CG    . PRO A 1 552 ? -20.680 9.413   -31.381 1.000 20.875  0 551  PRO A CG    1 ? 
ATOM   4192 C CD    . PRO A 1 552 ? -19.237 9.713   -31.781 1.000 20.588  0 551  PRO A CD    1 ? 
ATOM   4193 N N     . ALA A 1 553 ? -19.709 12.191  -29.299 1.000 19.349  0 552  ALA A N     1 ? 
ATOM   4194 C CA    . ALA A 1 553 ? -19.638 12.771  -27.972 1.000 18.661  0 552  ALA A CA    1 ? 
ATOM   4195 C C     . ALA A 1 553 ? -18.156 12.900  -27.638 1.000 19.646  0 552  ALA A C     1 ? 
ATOM   4196 O O     . ALA A 1 553 ? -17.333 12.183  -28.191 1.000 20.377  0 552  ALA A O     1 ? 
ATOM   4197 C CB    . ALA A 1 553 ? -20.359 11.885  -27.006 1.000 20.550  0 552  ALA A CB    1 ? 
ATOM   4198 N N     . ILE A 1 554 ? -17.776 13.850  -26.784 1.000 19.981  0 553  ILE A N     1 ? 
ATOM   4199 C CA    . ILE A 1 554 ? -16.375 13.915  -26.405 1.000 19.331  0 553  ILE A CA    1 ? 
ATOM   4200 C C     . ILE A 1 554 ? -16.108 12.814  -25.379 1.000 17.666  0 553  ILE A C     1 ? 
ATOM   4201 O O     . ILE A 1 554 ? -16.883 12.598  -24.449 1.000 18.300  0 553  ILE A O     1 ? 
ATOM   4202 C CB    . ILE A 1 554 ? -15.975 15.309  -25.883 1.000 19.376  0 553  ILE A CB    1 ? 
ATOM   4203 C CG1   . ILE A 1 554 ? -14.436 15.398  -25.759 1.000 19.937  0 553  ILE A CG1   1 ? 
ATOM   4204 C CG2   . ILE A 1 554 ? -16.684 15.665  -24.572 1.000 19.647  0 553  ILE A CG2   1 ? 
ATOM   4205 C CD1   . ILE A 1 554 ? -13.949 16.799  -25.464 1.000 20.297  0 553  ILE A CD1   1 ? 
ATOM   4206 N N     . PRO A 1 555 ? -15.001 12.046  -25.500 1.000 18.285  0 554  PRO A N     1 ? 
ATOM   4207 C CA    . PRO A 1 555 ? -14.689 11.052  -24.468 1.000 16.907  0 554  PRO A CA    1 ? 
ATOM   4208 C C     . PRO A 1 555 ? -14.633 11.678  -23.077 1.000 15.989  0 554  PRO A C     1 ? 
ATOM   4209 O O     . PRO A 1 555 ? -14.213 12.837  -22.923 1.000 16.941  0 554  PRO A O     1 ? 
ATOM   4210 C CB    . PRO A 1 555 ? -13.315 10.499  -24.942 1.000 18.625  0 554  PRO A CB    1 ? 
ATOM   4211 C CG    . PRO A 1 555 ? -13.383 10.677  -26.474 1.000 18.728  0 554  PRO A CG    1 ? 
ATOM   4212 C CD    . PRO A 1 555 ? -14.060 12.053  -26.630 1.000 17.739  0 554  PRO A CD    1 ? 
ATOM   4213 N N     . ALA A 1 556 ? -15.014 10.891  -22.053 1.000 18.417  0 555  ALA A N     1 ? 
ATOM   4214 C CA    . ALA A 1 556 ? -14.937 11.377  -20.679 1.000 19.138  0 555  ALA A CA    1 ? 
ATOM   4215 C C     . ALA A 1 556 ? -13.537 11.164  -20.108 1.000 19.620  0 555  ALA A C     1 ? 
ATOM   4216 O O     . ALA A 1 556 ? -13.356 10.837  -18.934 1.000 19.008  0 555  ALA A O     1 ? 
ATOM   4217 C CB    . ALA A 1 556 ? -16.001 10.732  -19.856 1.000 20.224  0 555  ALA A CB    1 ? 
ATOM   4218 N N     . THR A 1 557 ? -12.531 11.455  -20.926 1.000 18.852  0 556  THR A N     1 ? 
ATOM   4219 C CA    . THR A 1 557 ? -11.138 11.177  -20.619 1.000 17.724  0 556  THR A CA    1 ? 
ATOM   4220 C C     . THR A 1 557 ? -10.275 11.640  -21.796 1.000 18.983  0 556  THR A C     1 ? 
ATOM   4221 O O     . THR A 1 557 ? -10.763 12.131  -22.806 1.000 17.991  0 556  THR A O     1 ? 
ATOM   4222 C CB    . THR A 1 557 ? -10.933 9.698   -20.257 1.000 18.233  0 556  THR A CB    1 ? 
ATOM   4223 O OG1   . THR A 1 557 ? -9.573  9.642   -19.812 1.000 17.936  0 556  THR A OG1   1 ? 
ATOM   4224 C CG2   . THR A 1 557 ? -11.162 8.770   -21.434 1.000 18.069  0 556  THR A CG2   1 ? 
ATOM   4225 N N     . HIS A 1 558 ? -8.961  11.494  -21.622 1.000 18.503  0 557  HIS A N     1 ? 
ATOM   4226 C CA    . HIS A 1 558 ? -7.971  11.735  -22.651 1.000 17.309  0 557  HIS A CA    1 ? 
ATOM   4227 C C     . HIS A 1 558 ? -8.375  10.997  -23.922 1.000 16.838  0 557  HIS A C     1 ? 
ATOM   4228 O O     . HIS A 1 558 ? -8.598  9.801   -23.862 1.000 16.645  0 557  HIS A O     1 ? 
ATOM   4229 C CB    . HIS A 1 558 ? -6.604  11.235  -22.150 1.000 16.868  0 557  HIS A CB    1 ? 
ATOM   4230 C CG    . HIS A 1 558 ? -6.283  11.740  -20.792 1.000 16.941  0 557  HIS A CG    1 ? 
ATOM   4231 N ND1   . HIS A 1 558 ? -5.708  12.965  -20.599 1.000 20.311  0 557  HIS A ND1   1 ? 
ATOM   4232 C CD2   . HIS A 1 558 ? -6.461  11.219  -19.581 1.000 21.972  0 557  HIS A CD2   1 ? 
ATOM   4233 C CE1   . HIS A 1 558 ? -5.593  13.190  -19.291 1.000 21.949  0 557  HIS A CE1   1 ? 
ATOM   4234 N NE2   . HIS A 1 558 ? -6.066  12.152  -18.653 1.000 21.442  0 557  HIS A NE2   1 ? 
ATOM   4235 N N     . PRO A 1 559 ? -8.571  11.698  -25.058 1.000 16.398  0 558  PRO A N     1 ? 
ATOM   4236 C CA    . PRO A 1 559 ? -9.203  11.095  -26.243 1.000 16.133  0 558  PRO A CA    1 ? 
ATOM   4237 C C     . PRO A 1 559 ? -8.381  10.313  -27.268 1.000 16.523  0 558  PRO A C     1 ? 
ATOM   4238 O O     . PRO A 1 559 ? -8.974  9.754   -28.192 1.000 15.595  0 558  PRO A O     1 ? 
ATOM   4239 C CB    . PRO A 1 559 ? -9.812  12.353  -26.902 1.000 17.745  0 558  PRO A CB    1 ? 
ATOM   4240 C CG    . PRO A 1 559 ? -8.785  13.400  -26.644 1.000 17.548  0 558  PRO A CG    1 ? 
ATOM   4241 C CD    . PRO A 1 559 ? -8.424  13.163  -25.189 1.000 17.043  0 558  PRO A CD    1 ? 
ATOM   4242 N N     . MET A 1 560 ? -7.042  10.351  -27.163 1.000 15.504  0 559  MET A N     1 ? 
ATOM   4243 C CA    . MET A 1 560 ? -6.176  9.711   -28.128 1.000 15.666  0 559  MET A CA    1 ? 
ATOM   4244 C C     . MET A 1 560 ? -6.585  8.252   -28.328 1.000 15.956  0 559  MET A C     1 ? 
ATOM   4245 O O     . MET A 1 560 ? -6.667  7.782   -29.466 1.000 14.244  0 559  MET A O     1 ? 
ATOM   4246 C CB    . MET A 1 560 ? -4.714  9.827   -27.684 1.000 16.502  0 559  MET A CB    1 ? 
ATOM   4247 C CG    . MET A 1 560 ? -3.822  8.861   -28.367 1.000 19.019  0 559  MET A CG    1 ? 
ATOM   4248 S SD    . MET A 1 560 ? -2.067  9.026   -27.982 1.000 18.047  0 559  MET A SD    1 ? 
ATOM   4249 C CE    . MET A 1 560 ? -2.047  8.774   -26.207 1.000 18.634  0 559  MET A CE    1 ? 
ATOM   4250 N N     . ALA A 1 561 ? -6.868  7.532   -27.237 1.000 14.999  0 560  ALA A N     1 ? 
ATOM   4251 C CA    . ALA A 1 561 ? -7.189  6.111   -27.370 1.000 17.241  0 560  ALA A CA    1 ? 
ATOM   4252 C C     . ALA A 1 561 ? -8.513  5.878   -28.119 1.000 16.126  0 560  ALA A C     1 ? 
ATOM   4253 O O     . ALA A 1 561 ? -8.611  4.981   -28.990 1.000 16.884  0 560  ALA A O     1 ? 
ATOM   4254 C CB    . ALA A 1 561 ? -7.210  5.451   -26.023 1.000 17.032  0 560  ALA A CB    1 ? 
ATOM   4255 N N     . ALA A 1 562 ? -9.546  6.669   -27.795 1.000 15.096  0 561  ALA A N     1 ? 
ATOM   4256 C CA    . ALA A 1 562 ? -10.832 6.494   -28.461 1.000 15.746  0 561  ALA A CA    1 ? 
ATOM   4257 C C     . ALA A 1 562 ? -10.672 6.835   -29.949 1.000 16.908  0 561  ALA A C     1 ? 
ATOM   4258 O O     . ALA A 1 562 ? -11.253 6.185   -30.821 1.000 16.030  0 561  ALA A O     1 ? 
ATOM   4259 C CB    . ALA A 1 562 ? -11.847 7.402   -27.822 1.000 16.545  0 561  ALA A CB    1 ? 
ATOM   4260 N N     . ILE A 1 563 ? -9.827  7.828   -30.251 1.000 15.978  0 562  ILE A N     1 ? 
ATOM   4261 C CA    . ILE A 1 563 ? -9.583  8.153   -31.659 1.000 17.618  0 562  ILE A CA    1 ? 
ATOM   4262 C C     . ILE A 1 563 ? -8.863  6.999   -32.364 1.000 17.255  0 562  ILE A C     1 ? 
ATOM   4263 O O     . ILE A 1 563 ? -9.186  6.629   -33.514 1.000 18.090  0 562  ILE A O     1 ? 
ATOM   4264 C CB    . ILE A 1 563 ? -8.854  9.497   -31.783 1.000 17.320  0 562  ILE A CB    1 ? 
ATOM   4265 C CG1   . ILE A 1 563 ? -9.820  10.653  -31.434 1.000 17.519  0 562  ILE A CG1   1 ? 
ATOM   4266 C CG2   . ILE A 1 563 ? -8.283  9.709   -33.191 1.000 18.255  0 562  ILE A CG2   1 ? 
ATOM   4267 C CD1   . ILE A 1 563 ? -9.139  11.986  -31.214 1.000 16.673  0 562  ILE A CD1   1 ? 
ATOM   4268 N N     . TYR A 1 564 ? -7.852  6.431   -31.694 1.000 17.487  0 563  TYR A N     1 ? 
ATOM   4269 C CA    . TYR A 1 564 ? -7.196  5.252   -32.234 1.000 17.239  0 563  TYR A CA    1 ? 
ATOM   4270 C C     . TYR A 1 564 ? -8.235  4.173   -32.559 1.000 16.243  0 563  TYR A C     1 ? 
ATOM   4271 O O     . TYR A 1 564 ? -8.143  3.539   -33.605 1.000 16.958  0 563  TYR A O     1 ? 
ATOM   4272 C CB    . TYR A 1 564 ? -6.175  4.699   -31.241 1.000 16.937  0 563  TYR A CB    1 ? 
ATOM   4273 C CG    . TYR A 1 564 ? -4.747  5.211   -31.372 1.000 17.213  0 563  TYR A CG    1 ? 
ATOM   4274 C CD1   . TYR A 1 564 ? -4.089  5.205   -32.586 1.000 18.639  0 563  TYR A CD1   1 ? 
ATOM   4275 C CD2   . TYR A 1 564 ? -4.025  5.583   -30.254 1.000 17.873  0 563  TYR A CD2   1 ? 
ATOM   4276 C CE1   . TYR A 1 564 ? -2.768  5.606   -32.707 1.000 17.812  0 563  TYR A CE1   1 ? 
ATOM   4277 C CE2   . TYR A 1 564 ? -2.704  6.004   -30.358 1.000 17.214  0 563  TYR A CE2   1 ? 
ATOM   4278 C CZ    . TYR A 1 564 ? -2.074  6.006   -31.586 1.000 18.920  0 563  TYR A CZ    1 ? 
ATOM   4279 O OH    . TYR A 1 564 ? -0.770  6.384   -31.685 1.000 19.565  0 563  TYR A OH    1 ? 
ATOM   4280 N N     . LEU A 1 565 ? -9.123  3.863   -31.614 1.000 17.078  0 564  LEU A N     1 ? 
ATOM   4281 C CA    . LEU A 1 565 ? -10.095 2.775   -31.803 1.000 17.882  0 564  LEU A CA    1 ? 
ATOM   4282 C C     . LEU A 1 565 ? -11.090 3.081   -32.927 1.000 18.536  0 564  LEU A C     1 ? 
ATOM   4283 O O     . LEU A 1 565 ? -11.436 2.184   -33.714 1.000 17.724  0 564  LEU A O     1 ? 
ATOM   4284 C CB    . LEU A 1 565 ? -10.832 2.393   -30.536 1.000 18.257  0 564  LEU A CB    1 ? 
ATOM   4285 C CG    . LEU A 1 565 ? -9.942  2.069   -29.339 1.000 22.111  0 564  LEU A CG    1 ? 
ATOM   4286 C CD1   . LEU A 1 565 ? -10.741 1.372   -28.258 1.000 22.268  0 564  LEU A CD1   1 ? 
ATOM   4287 C CD2   . LEU A 1 565 ? -8.658  1.320   -29.665 1.000 22.094  0 564  LEU A CD2   1 ? 
ATOM   4288 N N     . LEU A 1 566 ? -11.548 4.330   -32.994 1.000 17.509  0 565  LEU A N     1 ? 
ATOM   4289 C CA    . LEU A 1 566 ? -12.372 4.749   -34.107 1.000 16.824  0 565  LEU A CA    1 ? 
ATOM   4290 C C     . LEU A 1 566 ? -11.648 4.529   -35.425 1.000 17.445  0 565  LEU A C     1 ? 
ATOM   4291 O O     . LEU A 1 566 ? -12.275 4.011   -36.367 1.000 21.166  0 565  LEU A O     1 ? 
ATOM   4292 C CB    . LEU A 1 566 ? -12.907 6.172   -33.965 1.000 18.162  0 565  LEU A CB    1 ? 
ATOM   4293 C CG    . LEU A 1 566 ? -13.827 6.620   -35.114 1.000 20.447  0 565  LEU A CG    1 ? 
ATOM   4294 C CD1   . LEU A 1 566 ? -15.173 7.081   -34.597 1.000 24.151  0 565  LEU A CD1   1 ? 
ATOM   4295 C CD2   . LEU A 1 566 ? -13.158 7.699   -35.920 1.000 21.069  0 565  LEU A CD2   1 ? 
ATOM   4296 N N     . ALA A 1 567 ? -10.347 4.870   -35.495 1.000 17.132  0 566  ALA A N     1 ? 
ATOM   4297 C CA    . ALA A 1 567 ? -9.579  4.678   -36.720 1.000 17.669  0 566  ALA A CA    1 ? 
ATOM   4298 C C     . ALA A 1 567 ? -9.387  3.192   -37.005 1.000 17.064  0 566  ALA A C     1 ? 
ATOM   4299 O O     . ALA A 1 567 ? -9.410  2.763   -38.153 1.000 16.680  0 566  ALA A O     1 ? 
ATOM   4300 C CB    . ALA A 1 567 ? -8.232  5.394   -36.636 1.000 17.387  0 566  ALA A CB    1 ? 
ATOM   4301 N N     . GLU A 1 568 ? -9.177  2.375   -35.975 1.000 16.053  0 567  GLU A N     1 ? 
ATOM   4302 C CA    . GLU A 1 568 ? -9.051  0.932   -36.190 1.000 17.315  0 567  GLU A CA    1 ? 
ATOM   4303 C C     . GLU A 1 568 ? -10.308 0.351   -36.827 1.000 16.407  0 567  GLU A C     1 ? 
ATOM   4304 O O     . GLU A 1 568 ? -10.221 -0.457  -37.751 1.000 19.312  0 567  GLU A O     1 ? 
ATOM   4305 C CB    . GLU A 1 568 ? -8.807  0.187   -34.881 1.000 16.767  0 567  GLU A CB    1 ? 
ATOM   4306 C CG    . GLU A 1 568 ? -7.417  0.434   -34.296 1.000 18.629  0 567  GLU A CG    1 ? 
ATOM   4307 C CD    . GLU A 1 568 ? -6.229  -0.249  -34.955 1.000 21.386  0 567  GLU A CD    1 ? 
ATOM   4308 O OE1   . GLU A 1 568 ? -6.333  -0.702  -36.130 1.000 22.707  0 567  GLU A OE1   1 ? 
ATOM   4309 O OE2   . GLU A 1 568 ? -5.145  -0.258  -34.304 1.000 21.451  0 567  GLU A OE2   1 ? 
ATOM   4310 N N     . ARG A 1 569 ? -11.488 0.732   -36.319 1.000 17.706  0 568  ARG A N     1 ? 
ATOM   4311 C CA    . ARG A 1 569 ? -12.709 0.188   -36.886 1.000 17.478  0 568  ARG A CA    1 ? 
ATOM   4312 C C     . ARG A 1 569 ? -12.981 0.780   -38.261 1.000 18.482  0 568  ARG A C     1 ? 
ATOM   4313 O O     . ARG A 1 569 ? -13.399 0.046   -39.165 1.000 19.637  0 568  ARG A O     1 ? 
ATOM   4314 C CB    . ARG A 1 569 ? -13.910 0.412   -35.999 1.000 18.195  0 568  ARG A CB    1 ? 
ATOM   4315 C CG    . ARG A 1 569 ? -15.107 -0.222  -36.673 1.000 18.626  0 568  ARG A CG    1 ? 
ATOM   4316 C CD    . ARG A 1 569 ? -16.270 -0.326  -35.741 1.000 23.865  0 568  ARG A CD    1 ? 
ATOM   4317 N NE    . ARG A 1 569 ? -17.308 -1.125  -36.410 1.000 23.785  0 568  ARG A NE    1 ? 
ATOM   4318 C CZ    . ARG A 1 569 ? -18.507 -0.709  -36.752 1.000 24.469  0 568  ARG A CZ    1 ? 
ATOM   4319 N NH1   . ARG A 1 569 ? -19.279 -1.526  -37.456 1.000 23.374  0 568  ARG A NH1   1 ? 
ATOM   4320 N NH2   . ARG A 1 569 ? -18.942 0.493   -36.424 1.000 22.458  0 568  ARG A NH2   1 ? 
ATOM   4321 N N     . GLY A 1 570 ? -12.748 2.094   -38.405 1.000 17.499  0 569  GLY A N     1 ? 
ATOM   4322 C CA    . GLY A 1 570 ? -12.948 2.759   -39.686 1.000 16.616  0 569  GLY A CA    1 ? 
ATOM   4323 C C     . GLY A 1 570 ? -12.133 2.105   -40.791 1.000 17.085  0 569  GLY A C     1 ? 
ATOM   4324 O O     . GLY A 1 570 ? -12.601 1.963   -41.938 1.000 18.507  0 569  GLY A O     1 ? 
ATOM   4325 N N     . SER A 1 571 ? -10.889 1.742   -40.458 1.000 17.317  0 570  SER A N     1 ? 
ATOM   4326 C CA    . SER A 1 571 ? -10.035 1.042   -41.387 1.000 18.653  0 570  SER A CA    1 ? 
ATOM   4327 C C     . SER A 1 571 ? -10.684 -0.265  -41.848 1.000 18.622  0 570  SER A C     1 ? 
ATOM   4328 O O     . SER A 1 571 ? -10.681 -0.596  -43.043 1.000 16.455  0 570  SER A O     1 ? 
ATOM   4329 C CB    . SER A 1 571 ? -8.670  0.815   -40.794 1.000 19.977  0 570  SER A CB    1 ? 
ATOM   4330 O OG    . SER A 1 571 ? -8.034  2.063   -40.538 1.000 21.205  0 570  SER A OG    1 ? 
ATOM   4331 N N     . ASP A 1 572 ? -11.236 -1.027  -40.911 1.000 17.070  0 571  ASP A N     1 ? 
ATOM   4332 C CA    . ASP A 1 572 ? -11.914 -2.263  -41.255 1.000 19.546  0 571  ASP A CA    1 ? 
ATOM   4333 C C     . ASP A 1 572 ? -13.183 -2.040  -42.078 1.000 20.540  0 571  ASP A C     1 ? 
ATOM   4334 O O     . ASP A 1 572 ? -13.550 -2.889  -42.912 1.000 19.025  0 571  ASP A O     1 ? 
ATOM   4335 C CB    . ASP A 1 572 ? -12.232 -3.097  -40.022 1.000 20.942  0 571  ASP A CB    1 ? 
ATOM   4336 C CG    . ASP A 1 572 ? -11.198 -4.146  -39.609 1.000 24.821  0 571  ASP A CG    1 ? 
ATOM   4337 O OD1   . ASP A 1 572 ? -10.048 -4.143  -40.158 1.000 25.117  0 571  ASP A OD1   1 ? 
ATOM   4338 O OD2   . ASP A 1 572 ? -11.541 -4.936  -38.694 1.000 24.551  0 571  ASP A OD2   1 ? 
ATOM   4339 N N     . LEU A 1 573 ? -13.907 -0.943  -41.816 1.000 19.151  0 572  LEU A N     1 ? 
ATOM   4340 C CA    . LEU A 1 573 ? -15.113 -0.615  -42.564 1.000 18.029  0 572  LEU A CA    1 ? 
ATOM   4341 C C     . LEU A 1 573 ? -14.764 -0.340  -44.029 1.000 18.799  0 572  LEU A C     1 ? 
ATOM   4342 O O     . LEU A 1 573 ? -15.498 -0.802  -44.897 1.000 18.957  0 572  LEU A O     1 ? 
ATOM   4343 C CB    . LEU A 1 573 ? -15.852 0.590   -41.991 1.000 20.420  0 572  LEU A CB    1 ? 
ATOM   4344 C CG    . LEU A 1 573 ? -16.446 0.403   -40.600 1.000 22.809  0 572  LEU A CG    1 ? 
ATOM   4345 C CD1   . LEU A 1 573 ? -17.138 1.651   -40.126 1.000 24.543  0 572  LEU A CD1   1 ? 
ATOM   4346 C CD2   . LEU A 1 573 ? -17.380 -0.791  -40.609 1.000 25.276  0 572  LEU A CD2   1 ? 
ATOM   4347 N N     . ILE A 1 574 ? -13.628 0.321   -44.275 1.000 17.101  0 573  ILE A N     1 ? 
ATOM   4348 C CA    . ILE A 1 574 ? -13.151 0.567   -45.623 1.000 17.531  0 573  ILE A CA    1 ? 
ATOM   4349 C C     . ILE A 1 574 ? -12.789 -0.766  -46.260 1.000 18.169  0 573  ILE A C     1 ? 
ATOM   4350 O O     . ILE A 1 574 ? -13.171 -1.014  -47.399 1.000 17.828  0 573  ILE A O     1 ? 
ATOM   4351 C CB    . ILE A 1 574 ? -11.965 1.546   -45.650 1.000 17.058  0 573  ILE A CB    1 ? 
ATOM   4352 C CG1   . ILE A 1 574 ? -12.399 2.953   -45.210 1.000 18.558  0 573  ILE A CG1   1 ? 
ATOM   4353 C CG2   . ILE A 1 574 ? -11.336 1.622   -47.034 1.000 18.335  0 573  ILE A CG2   1 ? 
ATOM   4354 C CD1   . ILE A 1 574 ? -11.221 3.851   -44.915 1.000 18.697  0 573  ILE A CD1   1 ? 
ATOM   4355 N N     . LYS A 1 575 ? -12.027 -1.607  -45.536 1.000 17.078  0 574  LYS A N     1 ? 
ATOM   4356 C CA    . LYS A 1 575 ? -11.633 -2.899  -46.090 1.000 19.317  0 574  LYS A CA    1 ? 
ATOM   4357 C C     . LYS A 1 575 ? -12.851 -3.760  -46.450 1.000 20.139  0 574  LYS A C     1 ? 
ATOM   4358 O O     . LYS A 1 575 ? -12.840 -4.465  -47.477 1.000 21.522  0 574  LYS A O     1 ? 
ATOM   4359 C CB    . LYS A 1 575 ? -10.691 -3.638  -45.141 1.000 19.052  0 574  LYS A CB    1 ? 
ATOM   4360 C CG    . LYS A 1 575 ? -9.345  -3.040  -45.001 1.000 18.591  0 574  LYS A CG    1 ? 
ATOM   4361 C CD    . LYS A 1 575 ? -8.516  -3.726  -43.916 1.000 21.112  0 574  LYS A CD    1 ? 
ATOM   4362 C CE    . LYS A 1 575 ? -7.212  -3.042  -43.766 1.000 21.101  0 574  LYS A CE    1 ? 
ATOM   4363 N NZ    . LYS A 1 575 ? -6.360  -3.736  -42.790 1.000 22.147  0 574  LYS A NZ    1 ? 
ATOM   4364 N N     . GLN A 1 576 ? -13.892 -3.706  -45.617 1.000 19.060  0 575  GLN A N     1 ? 
ATOM   4365 C CA    . GLN A 1 576 ? -15.101 -4.483  -45.849 1.000 22.012  0 575  GLN A CA    1 ? 
ATOM   4366 C C     . GLN A 1 576 ? -15.868 -3.980  -47.066 1.000 22.103  0 575  GLN A C     1 ? 
ATOM   4367 O O     . GLN A 1 576 ? -16.375 -4.768  -47.864 1.000 20.428  0 575  GLN A O     1 ? 
ATOM   4368 C CB    . GLN A 1 576 ? -15.970 -4.493  -44.602 1.000 26.389  0 575  GLN A CB    1 ? 
ATOM   4369 C CG    . GLN A 1 576 ? -15.377 -5.391  -43.517 1.000 32.165  0 575  GLN A CG    1 ? 
ATOM   4370 C CD    . GLN A 1 576 ? -15.903 -5.090  -42.128 1.000 36.880  0 575  GLN A CD    1 ? 
ATOM   4371 O OE1   . GLN A 1 576 ? -16.828 -4.297  -41.934 1.000 41.291  0 575  GLN A OE1   1 ? 
ATOM   4372 N NE2   . GLN A 1 576 ? -15.292 -5.713  -41.134 1.000 37.238  0 575  GLN A NE2   1 ? 
ATOM   4373 N N     . LYS A 1 577 ? -16.011 -2.661  -47.180 1.000 22.089  0 576  LYS A N     1 ? 
ATOM   4374 C CA    . LYS A 1 577 ? -16.781 -2.099  -48.270 1.000 23.615  0 576  LYS A CA    1 ? 
ATOM   4375 C C     . LYS A 1 577 ? -16.140 -2.440  -49.601 1.000 21.464  0 576  LYS A C     1 ? 
ATOM   4376 O O     . LYS A 1 577 ? -16.848 -2.791  -50.545 1.000 22.094  0 576  LYS A O     1 ? 
ATOM   4377 C CB    . LYS A 1 577 ? -16.886 -0.584  -48.100 1.000 24.560  0 576  LYS A CB    1 ? 
ATOM   4378 C CG    . LYS A 1 577 ? -17.583 0.089   -49.243 1.000 27.113  0 576  LYS A CG    1 ? 
ATOM   4379 C CD    . LYS A 1 577 ? -17.923 1.541   -48.962 1.000 30.070  0 576  LYS A CD    1 ? 
ATOM   4380 C CE    . LYS A 1 577 ? -18.396 2.241   -50.199 1.000 35.316  0 576  LYS A CE    1 ? 
ATOM   4381 N NZ    . LYS A 1 577 ? -19.348 3.307   -49.879 1.000 46.575  0 576  LYS A NZ    1 ? 
ATOM   4382 N N     . TRP A 1 578 ? -14.805 -2.298  -49.679 1.000 17.625  0 577  TRP A N     1 ? 
ATOM   4383 C CA    . TRP A 1 578 ? -14.112 -2.410  -50.945 1.000 18.316  0 577  TRP A CA    1 ? 
ATOM   4384 C C     . TRP A 1 578 ? -13.563 -3.821  -51.178 1.000 19.634  0 577  TRP A C     1 ? 
ATOM   4385 O O     . TRP A 1 578 ? -12.889 -4.072  -52.184 1.000 19.899  0 577  TRP A O     1 ? 
ATOM   4386 C CB    . TRP A 1 578 ? -13.017 -1.345  -50.992 1.000 18.315  0 577  TRP A CB    1 ? 
ATOM   4387 C CG    . TRP A 1 578 ? -13.598 0.030   -51.095 1.000 19.054  0 577  TRP A CG    1 ? 
ATOM   4388 C CD1   . TRP A 1 578 ? -13.905 0.886   -50.076 1.000 19.321  0 577  TRP A CD1   1 ? 
ATOM   4389 C CD2   . TRP A 1 578 ? -14.036 0.668   -52.318 1.000 18.145  0 577  TRP A CD2   1 ? 
ATOM   4390 N NE1   . TRP A 1 578 ? -14.465 2.029   -50.582 1.000 19.923  0 577  TRP A NE1   1 ? 
ATOM   4391 C CE2   . TRP A 1 578 ? -14.560 1.925   -51.953 1.000 19.864  0 577  TRP A CE2   1 ? 
ATOM   4392 C CE3   . TRP A 1 578 ? -14.024 0.299   -53.676 1.000 21.773  0 577  TRP A CE3   1 ? 
ATOM   4393 C CZ2   . TRP A 1 578 ? -15.055 2.825   -52.898 1.000 18.496  0 577  TRP A CZ2   1 ? 
ATOM   4394 C CZ3   . TRP A 1 578 ? -14.501 1.191   -54.617 1.000 20.398  0 577  TRP A CZ3   1 ? 
ATOM   4395 C CH2   . TRP A 1 578 ? -15.024 2.432   -54.226 1.000 21.400  0 577  TRP A CH2   1 ? 
ATOM   4396 N N     . LYS A 1 579 ? -13.796 -4.719  -50.206 1.000 20.145  0 578  LYS A N     1 ? 
ATOM   4397 C CA    . LYS A 1 579 ? -13.429 -6.127  -50.287 1.000 20.992  0 578  LYS A CA    1 ? 
ATOM   4398 C C     . LYS A 1 579 ? -11.934 -6.250  -50.518 1.000 21.224  0 578  LYS A C     1 ? 
ATOM   4399 O O     . LYS A 1 579 ? -11.466 -6.946  -51.421 1.000 21.985  0 578  LYS A O     1 ? 
ATOM   4400 C CB    . LYS A 1 579 ? -14.241 -6.839  -51.372 1.000 23.533  0 578  LYS A CB    1 ? 
ATOM   4401 C CG    . LYS A 1 579 ? -15.750 -6.706  -51.240 1.000 30.171  0 578  LYS A CG    1 ? 
ATOM   4402 C CD    . LYS A 1 579 ? -16.528 -7.927  -51.698 1.000 42.483  0 578  LYS A CD    1 ? 
ATOM   4403 C CE    . LYS A 1 579 ? -16.700 -8.845  -50.523 1.000 52.568  0 578  LYS A CE    1 ? 
ATOM   4404 N NZ    . LYS A 1 579 ? -17.363 -10.107 -50.864 1.000 57.994  0 578  LYS A NZ    1 ? 
ATOM   4405 N N     . LEU A 1 580 ? -11.166 -5.535  -49.701 1.000 20.335  0 579  LEU A N     1 ? 
ATOM   4406 C CA    . LEU A 1 580 ? -9.720  -5.527  -49.821 1.000 22.454  0 579  LEU A CA    1 ? 
ATOM   4407 C C     . LEU A 1 580 ? -9.103  -6.836  -49.241 1.000 27.369  0 579  LEU A C     1 ? 
ATOM   4408 O O     . LEU A 1 580 ? -7.929  -7.101  -49.576 1.000 30.960  0 579  LEU A O     1 ? 
ATOM   4409 C CB    . LEU A 1 580 ? -9.225  -4.286  -49.091 1.000 25.862  0 579  LEU A CB    1 ? 
ATOM   4410 C CG    . LEU A 1 580 ? -8.979  -3.017  -49.914 1.000 31.942  0 579  LEU A CG    1 ? 
ATOM   4411 C CD1   . LEU A 1 580 ? -9.701  -2.885  -51.224 1.000 26.697  0 579  LEU A CD1   1 ? 
ATOM   4412 C CD2   . LEU A 1 580 ? -9.099  -1.769  -49.065 1.000 27.506  0 579  LEU A CD2   1 ? 
ATOM   4413 O OXT   . LEU A 1 580 ? -9.755  -7.503  -48.402 1.000 28.326  0 579  LEU A OXT   1 ? 
HETATM 4414 P PA    . FAD B 2 .   ? -4.249  15.029  -35.116 1.000 16.226  0 600  FAD A PA    1 ? 
HETATM 4415 O O1A   . FAD B 2 .   ? -3.430  13.953  -34.516 1.000 15.071  0 600  FAD A O1A   1 ? 
HETATM 4416 O O2A   . FAD B 2 .   ? -4.040  16.422  -34.667 1.000 17.071  0 600  FAD A O2A   1 ? 
HETATM 4417 O O5B   . FAD B 2 .   ? -3.938  14.833  -36.671 1.000 15.720  0 600  FAD A O5B   1 ? 
HETATM 4418 C C5B   . FAD B 2 .   ? -4.303  15.815  -37.640 1.000 16.738  0 600  FAD A C5B   1 ? 
HETATM 4419 C C4B   . FAD B 2 .   ? -3.217  15.861  -38.667 1.000 17.145  0 600  FAD A C4B   1 ? 
HETATM 4420 O O4B   . FAD B 2 .   ? -3.686  16.484  -39.901 1.000 18.900  0 600  FAD A O4B   1 ? 
HETATM 4421 C C3B   . FAD B 2 .   ? -1.995  16.656  -38.200 1.000 17.110  0 600  FAD A C3B   1 ? 
HETATM 4422 O O3B   . FAD B 2 .   ? -0.844  15.866  -38.490 1.000 18.904  0 600  FAD A O3B   1 ? 
HETATM 4423 C C2B   . FAD B 2 .   ? -2.160  17.971  -38.970 1.000 16.865  0 600  FAD A C2B   1 ? 
HETATM 4424 O O2B   . FAD B 2 .   ? -0.951  18.647  -39.214 1.000 18.045  0 600  FAD A O2B   1 ? 
HETATM 4425 C C1B   . FAD B 2 .   ? -2.762  17.486  -40.283 1.000 16.039  0 600  FAD A C1B   1 ? 
HETATM 4426 N N9A   . FAD B 2 .   ? -3.513  18.496  -41.013 1.000 15.848  0 600  FAD A N9A   1 ? 
HETATM 4427 C C8A   . FAD B 2 .   ? -4.460  19.373  -40.535 1.000 16.017  0 600  FAD A C8A   1 ? 
HETATM 4428 N N7A   . FAD B 2 .   ? -4.996  20.141  -41.460 1.000 17.132  0 600  FAD A N7A   1 ? 
HETATM 4429 C C5A   . FAD B 2 .   ? -4.386  19.713  -42.637 1.000 17.506  0 600  FAD A C5A   1 ? 
HETATM 4430 C C6A   . FAD B 2 .   ? -4.530  20.112  -43.978 1.000 20.542  0 600  FAD A C6A   1 ? 
HETATM 4431 N N6A   . FAD B 2 .   ? -5.378  21.055  -44.386 1.000 22.493  0 600  FAD A N6A   1 ? 
HETATM 4432 N N1A   . FAD B 2 .   ? -3.764  19.485  -44.905 1.000 18.635  0 600  FAD A N1A   1 ? 
HETATM 4433 C C2A   . FAD B 2 .   ? -2.914  18.531  -44.494 1.000 21.617  0 600  FAD A C2A   1 ? 
HETATM 4434 N N3A   . FAD B 2 .   ? -2.696  18.073  -43.258 1.000 17.878  0 600  FAD A N3A   1 ? 
HETATM 4435 C C4A   . FAD B 2 .   ? -3.470  18.705  -42.373 1.000 17.404  0 600  FAD A C4A   1 ? 
HETATM 4436 N N1    . FAD B 2 .   ? -4.944  13.108  -25.679 1.000 16.450  0 600  FAD A N1    1 ? 
HETATM 4437 C C2    . FAD B 2 .   ? -4.731  11.993  -24.927 1.000 16.497  0 600  FAD A C2    1 ? 
HETATM 4438 O O2    . FAD B 2 .   ? -5.474  11.020  -24.994 1.000 16.796  0 600  FAD A O2    1 ? 
HETATM 4439 N N3    . FAD B 2 .   ? -3.700  11.999  -24.003 1.000 18.269  0 600  FAD A N3    1 ? 
HETATM 4440 C C4    . FAD B 2 .   ? -2.909  13.091  -23.648 1.000 18.367  0 600  FAD A C4    1 ? 
HETATM 4441 O O4    . FAD B 2 .   ? -1.969  12.945  -22.892 1.000 16.471  0 600  FAD A O4    1 ? 
HETATM 4442 C C4X   . FAD B 2 .   ? -3.076  14.222  -24.509 1.000 17.610  0 600  FAD A C4X   1 ? 
HETATM 4443 N N5    . FAD B 2 .   ? -2.314  15.297  -24.306 1.000 19.141  0 600  FAD A N5    1 ? 
HETATM 4444 C C5X   . FAD B 2 .   ? -2.393  16.300  -25.241 1.000 17.890  0 600  FAD A C5X   1 ? 
HETATM 4445 C C6    . FAD B 2 .   ? -1.466  17.368  -25.185 1.000 17.078  0 600  FAD A C6    1 ? 
HETATM 4446 C C7    . FAD B 2 .   ? -1.416  18.320  -26.177 1.000 16.914  0 600  FAD A C7    1 ? 
HETATM 4447 C C7M   . FAD B 2 .   ? -0.343  19.387  -26.156 1.000 18.142  0 600  FAD A C7M   1 ? 
HETATM 4448 C C8    . FAD B 2 .   ? -2.298  18.214  -27.270 1.000 17.763  0 600  FAD A C8    1 ? 
HETATM 4449 C C8M   . FAD B 2 .   ? -2.245  19.217  -28.392 1.000 18.593  0 600  FAD A C8M   1 ? 
HETATM 4450 C C9    . FAD B 2 .   ? -3.291  17.268  -27.263 1.000 16.445  0 600  FAD A C9    1 ? 
HETATM 4451 C C9A   . FAD B 2 .   ? -3.320  16.245  -26.313 1.000 16.598  0 600  FAD A C9A   1 ? 
HETATM 4452 N N10   . FAD B 2 .   ? -4.255  15.205  -26.355 1.000 16.927  0 600  FAD A N10   1 ? 
HETATM 4453 C C10   . FAD B 2 .   ? -4.129  14.133  -25.499 1.000 18.204  0 600  FAD A C10   1 ? 
HETATM 4454 C "C1'" . FAD B 2 .   ? -5.289  15.108  -27.404 1.000 16.735  0 600  FAD A "C1'" 1 ? 
HETATM 4455 C "C2'" . FAD B 2 .   ? -5.024  14.148  -28.554 1.000 15.525  0 600  FAD A "C2'" 1 ? 
HETATM 4456 O "O2'" . FAD B 2 .   ? -3.607  14.212  -28.768 1.000 16.540  0 600  FAD A "O2'" 1 ? 
HETATM 4457 C "C3'" . FAD B 2 .   ? -5.893  14.563  -29.731 1.000 14.297  0 600  FAD A "C3'" 1 ? 
HETATM 4458 O "O3'" . FAD B 2 .   ? -7.284  14.626  -29.365 1.000 15.214  0 600  FAD A "O3'" 1 ? 
HETATM 4459 C "C4'" . FAD B 2 .   ? -5.718  13.551  -30.884 1.000 14.388  0 600  FAD A "C4'" 1 ? 
HETATM 4460 O "O4'" . FAD B 2 .   ? -4.344  13.152  -31.044 1.000 16.290  0 600  FAD A "O4'" 1 ? 
HETATM 4461 C "C5'" . FAD B 2 .   ? -6.221  14.106  -32.214 1.000 13.621  0 600  FAD A "C5'" 1 ? 
HETATM 4462 O "O5'" . FAD B 2 .   ? -6.200  13.044  -33.183 1.000 14.232  0 600  FAD A "O5'" 1 ? 
HETATM 4463 P P     . FAD B 2 .   ? -6.633  13.381  -34.693 1.000 15.630  0 600  FAD A P     1 ? 
HETATM 4464 O O1P   . FAD B 2 .   ? -8.068  13.772  -34.693 1.000 14.605  0 600  FAD A O1P   1 ? 
HETATM 4465 O O2P   . FAD B 2 .   ? -6.134  12.265  -35.525 1.000 14.399  0 600  FAD A O2P   1 ? 
HETATM 4466 O O3P   . FAD B 2 .   ? -5.806  14.690  -35.005 1.000 15.018  0 600  FAD A O3P   1 ? 
HETATM 4467 C C8    . ANN C 3 .   ? -0.570  17.699  -16.873 1.000 35.018  0 601  ANN A C8    1 ? 
HETATM 4468 O O3    . ANN C 3 .   ? -1.032  16.362  -17.209 1.000 35.974  0 601  ANN A O3    1 ? 
HETATM 4469 C C5    . ANN C 3 .   ? -1.839  16.265  -18.284 1.000 27.571  0 601  ANN A C5    1 ? 
HETATM 4470 C C6    . ANN C 3 .   ? -1.941  15.004  -18.887 1.000 25.825  0 601  ANN A C6    1 ? 
HETATM 4471 C C7    . ANN C 3 .   ? -2.752  14.826  -20.015 1.000 25.637  0 601  ANN A C7    1 ? 
HETATM 4472 C C2    . ANN C 3 .   ? -3.442  15.956  -20.522 1.000 26.462  0 601  ANN A C2    1 ? 
HETATM 4473 C C3    . ANN C 3 .   ? -3.324  17.182  -19.893 1.000 26.883  0 601  ANN A C3    1 ? 
HETATM 4474 C C4    . ANN C 3 .   ? -2.546  17.381  -18.751 1.000 26.055  0 601  ANN A C4    1 ? 
HETATM 4475 C C1    . ANN C 3 .   ? -4.228  15.848  -21.679 1.000 27.003  0 601  ANN A C1    1 ? 
HETATM 4476 O O1    . ANN C 3 .   ? -4.823  14.778  -21.969 1.000 28.459  0 601  ANN A O1    1 ? 
HETATM 4477 O O2    . ANN C 3 .   ? -4.281  16.825  -22.468 1.000 25.672  0 601  ANN A O2    1 ? 
HETATM 4478 C C1    . GOL D 4 .   ? 6.875   32.925  -11.788 1.000 42.196  0 602  GOL A C1    1 ? 
HETATM 4479 O O1    . GOL D 4 .   ? 6.284   33.361  -10.572 1.000 32.282  0 602  GOL A O1    1 ? 
HETATM 4480 C C2    . GOL D 4 .   ? 6.623   33.878  -12.928 1.000 50.201  0 602  GOL A C2    1 ? 
HETATM 4481 O O2    . GOL D 4 .   ? 7.742   34.752  -13.041 1.000 53.285  0 602  GOL A O2    1 ? 
HETATM 4482 C C3    . GOL D 4 .   ? 5.324   34.657  -12.808 1.000 51.093  0 602  GOL A C3    1 ? 
HETATM 4483 O O3    . GOL D 4 .   ? 5.496   36.053  -13.047 1.000 45.705  0 602  GOL A O3    1 ? 
HETATM 4484 C C1    . GOL E 4 .   ? -6.454  35.445  -32.352 1.000 56.050  0 603  GOL A C1    1 ? 
HETATM 4485 O O1    . GOL E 4 .   ? -6.748  34.058  -32.476 1.000 71.437  0 603  GOL A O1    1 ? 
HETATM 4486 C C2    . GOL E 4 .   ? -7.710  36.293  -32.318 1.000 55.358  0 603  GOL A C2    1 ? 
HETATM 4487 O O2    . GOL E 4 .   ? -8.277  36.254  -31.008 1.000 44.319  0 603  GOL A O2    1 ? 
HETATM 4488 C C3    . GOL E 4 .   ? -8.729  35.935  -33.389 1.000 57.360  0 603  GOL A C3    1 ? 
HETATM 4489 O O3    . GOL E 4 .   ? -9.721  34.999  -32.957 1.000 55.132  0 603  GOL A O3    1 ? 
HETATM 4490 C C1    . GOL F 4 .   ? 0.276   -1.467  -39.413 1.000 34.328  0 604  GOL A C1    1 ? 
HETATM 4491 O O1    . GOL F 4 .   ? 0.116   -1.916  -40.755 1.000 25.111  0 604  GOL A O1    1 ? 
HETATM 4492 C C2    . GOL F 4 .   ? 1.170   -2.357  -38.588 1.000 40.345  0 604  GOL A C2    1 ? 
HETATM 4493 O O2    . GOL F 4 .   ? 2.173   -3.005  -39.370 1.000 39.941  0 604  GOL A O2    1 ? 
HETATM 4494 C C3    . GOL F 4 .   ? 1.834   -1.613  -37.448 1.000 44.855  0 604  GOL A C3    1 ? 
HETATM 4495 O O3    . GOL F 4 .   ? 1.985   -2.486  -36.339 1.000 54.216  0 604  GOL A O3    1 ? 
HETATM 4496 C C1    . GOL G 4 .   ? 14.689  19.630  -31.173 1.000 42.876  0 605  GOL A C1    1 ? 
HETATM 4497 O O1    . GOL G 4 .   ? 14.012  19.219  -29.987 1.000 31.310  0 605  GOL A O1    1 ? 
HETATM 4498 C C2    . GOL G 4 .   ? 16.158  19.906  -30.964 1.000 48.672  0 605  GOL A C2    1 ? 
HETATM 4499 O O2    . GOL G 4 .   ? 16.484  19.977  -29.581 1.000 47.778  0 605  GOL A O2    1 ? 
HETATM 4500 C C3    . GOL G 4 .   ? 17.043  18.867  -31.612 1.000 55.297  0 605  GOL A C3    1 ? 
HETATM 4501 O O3    . GOL G 4 .   ? 16.368  17.617  -31.660 1.000 43.879  0 605  GOL A O3    1 ? 
HETATM 4502 C C1    . GOL H 4 .   ? 8.049   16.390  -17.230 1.000 50.753  0 606  GOL A C1    1 ? 
HETATM 4503 O O1    . GOL H 4 .   ? 7.819   15.029  -16.870 1.000 43.139  0 606  GOL A O1    1 ? 
HETATM 4504 C C2    . GOL H 4 .   ? 9.506   16.825  -17.178 1.000 42.507  0 606  GOL A C2    1 ? 
HETATM 4505 O O2    . GOL H 4 .   ? 9.600   18.195  -16.757 1.000 54.493  0 606  GOL A O2    1 ? 
HETATM 4506 C C3    . GOL H 4 .   ? 10.364  15.931  -16.308 1.000 43.979  0 606  GOL A C3    1 ? 
HETATM 4507 O O3    . GOL H 4 .   ? 11.083  14.982  -17.090 1.000 43.842  0 606  GOL A O3    1 ? 
HETATM 4508 S S     . SO4 I 5 .   ? 9.809   25.144  1.455   1.000 70.119  0 607  SO4 A S     1 ? 
HETATM 4509 O O1    . SO4 I 5 .   ? 11.231  24.923  1.371   1.000 70.797  0 607  SO4 A O1    1 ? 
HETATM 4510 O O2    . SO4 I 5 .   ? 9.380   25.871  0.286   1.000 72.356  0 607  SO4 A O2    1 ? 
HETATM 4511 O O3    . SO4 I 5 .   ? 9.119   23.871  1.513   1.000 59.275  0 607  SO4 A O3    1 ? 
HETATM 4512 O O4    . SO4 I 5 .   ? 9.507   25.909  2.647   1.000 76.028  0 607  SO4 A O4    1 ? 
HETATM 4513 S S     . SO4 J 5 .   ? -17.468 -4.727  -37.758 1.000 48.345  0 608  SO4 A S     1 ? 
HETATM 4514 O O1    . SO4 J 5 .   ? -16.572 -5.425  -38.654 1.000 47.602  0 608  SO4 A O1    1 ? 
HETATM 4515 O O2    . SO4 J 5 .   ? -18.370 -3.920  -38.538 1.000 53.571  0 608  SO4 A O2    1 ? 
HETATM 4516 O O3    . SO4 J 5 .   ? -18.249 -5.673  -36.987 1.000 51.714  0 608  SO4 A O3    1 ? 
HETATM 4517 O O4    . SO4 J 5 .   ? -16.673 -3.876  -36.867 1.000 36.419  0 608  SO4 A O4    1 ? 
HETATM 4518 S S     . SO4 K 5 .   ? -23.252 30.100  -32.108 1.000 67.949  0 609  SO4 A S     1 ? 
HETATM 4519 O O1    . SO4 K 5 .   ? -22.179 31.061  -32.073 1.000 63.049  0 609  SO4 A O1    1 ? 
HETATM 4520 O O2    . SO4 K 5 .   ? -23.544 29.776  -33.478 1.000 65.414  0 609  SO4 A O2    1 ? 
HETATM 4521 O O3    . SO4 K 5 .   ? -22.861 28.904  -31.396 1.000 73.749  0 609  SO4 A O3    1 ? 
HETATM 4522 O O4    . SO4 K 5 .   ? -24.422 30.660  -31.495 1.000 69.732  0 609  SO4 A O4    1 ? 
HETATM 4523 S S     . SO4 L 5 .   ? 15.340  27.808  -22.365 1.000 78.372  0 610  SO4 A S     1 ? 
HETATM 4524 O O1    . SO4 L 5 .   ? 14.957  27.239  -23.631 1.000 76.098  0 610  SO4 A O1    1 ? 
HETATM 4525 O O2    . SO4 L 5 .   ? 14.787  29.134  -22.253 1.000 82.527  0 610  SO4 A O2    1 ? 
HETATM 4526 O O3    . SO4 L 5 .   ? 14.832  26.990  -21.292 1.000 76.921  0 610  SO4 A O3    1 ? 
HETATM 4527 O O4    . SO4 L 5 .   ? 16.779  27.879  -22.286 1.000 83.982  0 610  SO4 A O4    1 ? 
HETATM 4528 S S     . SO4 M 5 .   ? -10.116 28.063  2.666   1.000 71.463  0 611  SO4 A S     1 ? 
HETATM 4529 O O1    . SO4 M 5 .   ? -9.089  29.064  2.853   1.000 69.279  0 611  SO4 A O1    1 ? 
HETATM 4530 O O2    . SO4 M 5 .   ? -11.415 28.686  2.801   1.000 70.220  0 611  SO4 A O2    1 ? 
HETATM 4531 O O3    . SO4 M 5 .   ? -10.004 27.503  1.344   1.000 87.363  0 611  SO4 A O3    1 ? 
HETATM 4532 O O4    . SO4 M 5 .   ? -9.956  26.998  3.628   1.000 69.551  0 611  SO4 A O4    1 ? 
HETATM 4533 S S     . SO4 N 5 .   ? -6.903  10.451  7.412   1.000 66.177  0 612  SO4 A S     1 ? 
HETATM 4534 O O1    . SO4 N 5 .   ? -5.825  10.283  6.484   1.000 62.599  0 612  SO4 A O1    1 ? 
HETATM 4535 O O2    . SO4 N 5 .   ? -7.785  11.498  6.945   1.000 74.587  0 612  SO4 A O2    1 ? 
HETATM 4536 O O3    . SO4 N 5 .   ? -7.632  9.218   7.519   1.000 65.074  0 612  SO4 A O3    1 ? 
HETATM 4537 O O4    . SO4 N 5 .   ? -6.373  10.806  8.704   1.000 69.789  0 612  SO4 A O4    1 ? 
HETATM 4538 O O     . HOH O 6 .   ? 13.578  20.625  -26.145 1.000 32.675  0 701  HOH A O     1 ? 
HETATM 4539 O O     . HOH O 6 .   ? -17.466 25.364  -53.967 1.000 45.146  0 702  HOH A O     1 ? 
HETATM 4540 O O     . HOH O 6 .   ? 14.643  4.813   -26.970 1.000 29.910  0 703  HOH A O     1 ? 
HETATM 4541 O O     . HOH O 6 .   ? 4.032   16.188  -40.466 1.000 95.040  0 704  HOH A O     1 ? 
HETATM 4542 O O     . HOH O 6 .   ? -17.500 4.851   -50.295 1.000 36.830  0 705  HOH A O     1 ? 
HETATM 4543 O O     . HOH O 6 .   ? -12.923 36.760  -12.802 1.000 30.025  0 706  HOH A O     1 ? 
HETATM 4544 O O     . HOH O 6 .   ? 12.007  10.503  -11.513 1.000 31.321  0 707  HOH A O     1 ? 
HETATM 4545 O O     . HOH O 6 .   ? -9.807  34.229  -35.574 1.000 41.920  0 708  HOH A O     1 ? 
HETATM 4546 O O     . HOH O 6 .   ? -19.414 30.976  1.228   1.000 32.935  0 709  HOH A O     1 ? 
HETATM 4547 O O     . HOH O 6 .   ? 11.429  12.646  -33.016 1.000 20.666  0 710  HOH A O     1 ? 
HETATM 4548 O O     . HOH O 6 .   ? 0.028   33.232  -6.027  1.000 34.126  0 711  HOH A O     1 ? 
HETATM 4549 O O     . HOH O 6 .   ? -10.161 -7.735  -45.928 1.000 43.071  0 712  HOH A O     1 ? 
HETATM 4550 O O     . HOH O 6 .   ? 14.592  29.311  -10.750 1.000 40.628  0 713  HOH A O     1 ? 
HETATM 4551 O O     . HOH O 6 .   ? 13.785  3.501   -10.858 1.000 42.937  0 714  HOH A O     1 ? 
HETATM 4552 O O     . HOH O 6 .   ? -14.692 22.124  -54.181 1.000 40.788  0 715  HOH A O     1 ? 
HETATM 4553 O O     . HOH O 6 .   ? -26.095 33.492  -46.440 1.000 39.568  0 716  HOH A O     1 ? 
HETATM 4554 O O     . HOH O 6 .   ? 15.218  27.520  -7.976  1.000 41.180  0 717  HOH A O     1 ? 
HETATM 4555 O O     . HOH O 6 .   ? -8.589  -8.169  -31.803 1.000 24.792  0 718  HOH A O     1 ? 
HETATM 4556 O O     . HOH O 6 .   ? 9.879   8.663   -30.791 1.000 19.077  0 719  HOH A O     1 ? 
HETATM 4557 O O     . HOH O 6 .   ? -25.725 24.533  -20.334 1.000 40.796  0 720  HOH A O     1 ? 
HETATM 4558 O O     . HOH O 6 .   ? -9.620  1.871   -58.398 1.000 40.055  0 721  HOH A O     1 ? 
HETATM 4559 O O     . HOH O 6 .   ? 11.332  25.814  -19.450 1.000 37.625  0 722  HOH A O     1 ? 
HETATM 4560 O O     . HOH O 6 .   ? -20.102 27.318  -40.681 1.000 27.794  0 723  HOH A O     1 ? 
HETATM 4561 O O     . HOH O 6 .   ? -3.431  35.375  -41.041 1.000 41.624  0 724  HOH A O     1 ? 
HETATM 4562 O O     . HOH O 6 .   ? -20.730 1.318   -38.557 1.000 29.016  0 725  HOH A O     1 ? 
HETATM 4563 O O     . HOH O 6 .   ? 14.254  10.088  -35.285 1.000 44.608  0 726  HOH A O     1 ? 
HETATM 4564 O O     . HOH O 6 .   ? 0.625   6.839   -29.555 1.000 20.782  0 727  HOH A O     1 ? 
HETATM 4565 O O     . HOH O 6 .   ? -20.520 15.239  -58.578 1.000 36.380  0 728  HOH A O     1 ? 
HETATM 4566 O O     . HOH O 6 .   ? 17.635  18.787  -27.582 1.000 38.291  0 729  HOH A O     1 ? 
HETATM 4567 O O     . HOH O 6 .   ? -16.598 8.697   -57.822 1.000 50.930  0 730  HOH A O     1 ? 
HETATM 4568 O O     . HOH O 6 .   ? -10.925 25.181  0.628   1.000 32.991  0 731  HOH A O     1 ? 
HETATM 4569 O O     . HOH O 6 .   ? -1.160  -6.090  -11.021 1.000 29.577  0 732  HOH A O     1 ? 
HETATM 4570 O O     . HOH O 6 .   ? -5.026  -5.265  -39.513 1.000 34.376  0 733  HOH A O     1 ? 
HETATM 4571 O O     . HOH O 6 .   ? -28.337 4.229   -37.433 1.000 37.175  0 734  HOH A O     1 ? 
HETATM 4572 O O     . HOH O 6 .   ? 6.838   14.508  -19.704 1.000 25.174  0 735  HOH A O     1 ? 
HETATM 4573 O O     . HOH O 6 .   ? -19.750 29.461  -31.394 1.000 28.718  0 736  HOH A O     1 ? 
HETATM 4574 O O     . HOH O 6 .   ? -35.554 17.116  -13.816 1.000 34.292  0 737  HOH A O     1 ? 
HETATM 4575 O O     . HOH O 6 .   ? 5.485   12.120  -14.191 1.000 23.781  0 738  HOH A O     1 ? 
HETATM 4576 O O     . HOH O 6 .   ? -7.256  19.536  -36.689 1.000 19.264  0 739  HOH A O     1 ? 
HETATM 4577 O O     . HOH O 6 .   ? 0.390   9.310   -8.640  1.000 24.641  0 740  HOH A O     1 ? 
HETATM 4578 O O     . HOH O 6 .   ? -0.581  25.104  -43.559 1.000 33.596  0 741  HOH A O     1 ? 
HETATM 4579 O O     . HOH O 6 .   ? -15.760 11.958  -52.558 1.000 28.570  0 742  HOH A O     1 ? 
HETATM 4580 O O     . HOH O 6 .   ? -3.287  2.833   -57.754 1.000 31.427  0 743  HOH A O     1 ? 
HETATM 4581 O O     . HOH O 6 .   ? 12.452  12.732  -42.285 1.000 32.008  0 744  HOH A O     1 ? 
HETATM 4582 O O     . HOH O 6 .   ? -0.149  -1.801  -55.937 1.000 31.844  0 745  HOH A O     1 ? 
HETATM 4583 O O     . HOH O 6 .   ? -19.548 8.310   -25.876 1.000 22.657  0 746  HOH A O     1 ? 
HETATM 4584 O O     . HOH O 6 .   ? 3.660   20.287  -53.606 1.000 28.088  0 747  HOH A O     1 ? 
HETATM 4585 O O     . HOH O 6 .   ? -16.959 35.979  -17.892 1.000 26.164  0 748  HOH A O     1 ? 
HETATM 4586 O O     . HOH O 6 .   ? -22.122 -1.676  -37.961 1.000 30.927  0 749  HOH A O     1 ? 
HETATM 4587 O O     . HOH O 6 .   ? 4.429   19.014  -26.869 1.000 24.200  0 750  HOH A O     1 ? 
HETATM 4588 O O     . HOH O 6 .   ? 3.926   1.679   -10.925 1.000 26.116  0 751  HOH A O     1 ? 
HETATM 4589 O O     . HOH O 6 .   ? -3.094  19.188  -22.728 1.000 31.286  0 752  HOH A O     1 ? 
HETATM 4590 O O     . HOH O 6 .   ? 14.325  -1.603  -19.566 1.000 41.768  0 753  HOH A O     1 ? 
HETATM 4591 O O     . HOH O 6 .   ? 4.647   9.224   -16.534 1.000 17.999  0 754  HOH A O     1 ? 
HETATM 4592 O O     . HOH O 6 .   ? 3.828   31.903  -10.790 1.000 26.746  0 755  HOH A O     1 ? 
HETATM 4593 O O     . HOH O 6 .   ? -1.141  4.718   -57.458 1.000 32.763  0 756  HOH A O     1 ? 
HETATM 4594 O O     . HOH O 6 .   ? -2.653  -5.002  -34.393 1.000 21.558  0 757  HOH A O     1 ? 
HETATM 4595 O O     . HOH O 6 .   ? -3.038  1.872   -14.233 1.000 20.074  0 758  HOH A O     1 ? 
HETATM 4596 O O     . HOH O 6 .   ? 14.871  5.517   -15.083 1.000 31.037  0 759  HOH A O     1 ? 
HETATM 4597 O O     . HOH O 6 .   ? -7.936  -1.936  -37.879 1.000 18.868  0 760  HOH A O     1 ? 
HETATM 4598 O O     . HOH O 6 .   ? 15.770  12.531  -31.171 1.000 39.034  0 761  HOH A O     1 ? 
HETATM 4599 O O     . HOH O 6 .   ? -3.627  27.087  -7.845  1.000 18.982  0 762  HOH A O     1 ? 
HETATM 4600 O O     . HOH O 6 .   ? 10.096  13.973  -1.057  1.000 30.662  0 763  HOH A O     1 ? 
HETATM 4601 O O     . HOH O 6 .   ? -11.918 1.466   -19.182 1.000 21.665  0 764  HOH A O     1 ? 
HETATM 4602 O O     . HOH O 6 .   ? -13.832 27.812  -50.792 1.000 38.908  0 765  HOH A O     1 ? 
HETATM 4603 O O     . HOH O 6 .   ? 6.838   3.418   -50.692 1.000 39.466  0 766  HOH A O     1 ? 
HETATM 4604 O O     . HOH O 6 .   ? -25.919 15.889  -51.868 1.000 30.215  0 767  HOH A O     1 ? 
HETATM 4605 O O     . HOH O 6 .   ? 12.238  16.947  -38.793 1.000 37.867  0 768  HOH A O     1 ? 
HETATM 4606 O O     . HOH O 6 .   ? -20.786 -2.526  -21.919 1.000 32.578  0 769  HOH A O     1 ? 
HETATM 4607 O O     . HOH O 6 .   ? 5.839   16.122  -14.724 1.000 26.058  0 770  HOH A O     1 ? 
HETATM 4608 O O     . HOH O 6 .   ? -16.863 30.992  -22.710 1.000 23.938  0 771  HOH A O     1 ? 
HETATM 4609 O O     . HOH O 6 .   ? 22.185  17.163  -23.395 1.000 44.142  0 772  HOH A O     1 ? 
HETATM 4610 O O     . HOH O 6 .   ? 13.593  29.594  -15.558 1.000 33.986  0 773  HOH A O     1 ? 
HETATM 4611 O O     . HOH O 6 .   ? -19.180 9.821   -48.670 1.000 24.912  0 774  HOH A O     1 ? 
HETATM 4612 O O     . HOH O 6 .   ? 10.348  17.914  -42.605 1.000 24.601  0 775  HOH A O     1 ? 
HETATM 4613 O O     . HOH O 6 .   ? -5.723  34.884  -16.174 1.000 29.475  0 776  HOH A O     1 ? 
HETATM 4614 O O     . HOH O 6 .   ? -9.603  4.264   -19.838 1.000 17.570  0 777  HOH A O     1 ? 
HETATM 4615 O O     . HOH O 6 .   ? -21.020 1.997   -46.044 1.000 39.634  0 778  HOH A O     1 ? 
HETATM 4616 O O     . HOH O 6 .   ? -7.240  -1.245  -53.334 1.000 29.127  0 779  HOH A O     1 ? 
HETATM 4617 O O     . HOH O 6 .   ? 4.849   3.896   -9.952  1.000 31.584  0 780  HOH A O     1 ? 
HETATM 4618 O O     . HOH O 6 .   ? -12.806 3.888   -0.599  1.000 31.689  0 781  HOH A O     1 ? 
HETATM 4619 O O     . HOH O 6 .   ? -7.453  8.245   2.768   1.000 33.334  0 782  HOH A O     1 ? 
HETATM 4620 O O     . HOH O 6 .   ? 3.778   6.652   -17.288 1.000 22.143  0 783  HOH A O     1 ? 
HETATM 4621 O O     . HOH O 6 .   ? -16.639 23.823  -20.696 1.000 20.021  0 784  HOH A O     1 ? 
HETATM 4622 O O     . HOH O 6 .   ? 17.675  0.655   -23.639 1.000 49.958  0 785  HOH A O     1 ? 
HETATM 4623 O O     . HOH O 6 .   ? 6.540   25.995  -53.923 1.000 37.397  0 786  HOH A O     1 ? 
HETATM 4624 O O     . HOH O 6 .   ? -5.048  12.090  -38.011 1.000 15.125  0 787  HOH A O     1 ? 
HETATM 4625 O O     . HOH O 6 .   ? -3.929  -2.943  -6.207  1.000 36.901  0 788  HOH A O     1 ? 
HETATM 4626 O O     . HOH O 6 .   ? 8.556   18.773  -20.322 1.000 22.939  0 789  HOH A O     1 ? 
HETATM 4627 O O     . HOH O 6 .   ? -10.132 7.952   -25.235 1.000 19.928  0 790  HOH A O     1 ? 
HETATM 4628 O O     . HOH O 6 .   ? -31.756 17.521  -36.066 1.000 55.858  0 791  HOH A O     1 ? 
HETATM 4629 O O     . HOH O 6 .   ? -11.570 -0.864  -14.787 1.000 22.350  0 792  HOH A O     1 ? 
HETATM 4630 O O     . HOH O 6 .   ? -7.858  -2.607  -40.564 1.000 23.470  0 793  HOH A O     1 ? 
HETATM 4631 O O     . HOH O 6 .   ? -25.674 17.588  -41.222 1.000 31.638  0 794  HOH A O     1 ? 
HETATM 4632 O O     . HOH O 6 .   ? 15.333  25.754  -10.512 1.000 35.707  0 795  HOH A O     1 ? 
HETATM 4633 O O     . HOH O 6 .   ? 2.986   5.672   -14.704 1.000 20.579  0 796  HOH A O     1 ? 
HETATM 4634 O O     . HOH O 6 .   ? 2.897   15.592  10.632  1.000 54.236  0 797  HOH A O     1 ? 
HETATM 4635 O O     . HOH O 6 .   ? -9.605  -6.291  -37.360 1.000 27.720  0 798  HOH A O     1 ? 
HETATM 4636 O O     . HOH O 6 .   ? -5.572  34.569  -22.279 1.000 50.257  0 799  HOH A O     1 ? 
HETATM 4637 O O     . HOH O 6 .   ? -0.759  -6.563  -23.220 1.000 18.527  0 800  HOH A O     1 ? 
HETATM 4638 O O     . HOH O 6 .   ? -21.676 -3.378  -25.383 1.000 20.348  0 801  HOH A O     1 ? 
HETATM 4639 O O     . HOH O 6 .   ? 8.620   13.160  1.187   1.000 24.032  0 802  HOH A O     1 ? 
HETATM 4640 O O     . HOH O 6 .   ? -7.465  11.721  0.457   1.000 27.544  0 803  HOH A O     1 ? 
HETATM 4641 O O     . HOH O 6 .   ? 1.942   27.835  -20.124 1.000 45.290  0 804  HOH A O     1 ? 
HETATM 4642 O O     . HOH O 6 .   ? -11.912 35.348  -6.579  1.000 26.067  0 805  HOH A O     1 ? 
HETATM 4643 O O     . HOH O 6 .   ? -6.496  35.928  -45.608 1.000 28.517  0 806  HOH A O     1 ? 
HETATM 4644 O O     . HOH O 6 .   ? 8.150   6.005   -18.559 1.000 17.692  0 807  HOH A O     1 ? 
HETATM 4645 O O     . HOH O 6 .   ? -6.045  23.352  -58.899 1.000 37.428  0 808  HOH A O     1 ? 
HETATM 4646 O O     . HOH O 6 .   ? -6.849  -6.404  -42.531 1.000 29.780  0 809  HOH A O     1 ? 
HETATM 4647 O O     . HOH O 6 .   ? -3.434  18.842  -35.873 1.000 21.221  0 810  HOH A O     1 ? 
HETATM 4648 O O     . HOH O 6 .   ? 8.852   23.841  -1.570  1.000 24.498  0 811  HOH A O     1 ? 
HETATM 4649 O O     . HOH O 6 .   ? -10.001 -2.611  -12.502 1.000 38.282  0 812  HOH A O     1 ? 
HETATM 4650 O O     . HOH O 6 .   ? -10.085 -9.170  -52.195 1.000 28.601  0 813  HOH A O     1 ? 
HETATM 4651 O O     . HOH O 6 .   ? 4.290   -1.301  -17.283 1.000 21.076  0 814  HOH A O     1 ? 
HETATM 4652 O O     . HOH O 6 .   ? -11.316 28.407  -51.062 1.000 40.828  0 815  HOH A O     1 ? 
HETATM 4653 O O     . HOH O 6 .   ? 3.211   7.344   -12.413 1.000 20.482  0 816  HOH A O     1 ? 
HETATM 4654 O O     . HOH O 6 .   ? -10.235 29.706  -44.408 1.000 24.021  0 817  HOH A O     1 ? 
HETATM 4655 O O     . HOH O 6 .   ? -19.327 25.790  -38.617 1.000 26.002  0 818  HOH A O     1 ? 
HETATM 4656 O O     . HOH O 6 .   ? -15.133 -7.115  -29.698 1.000 22.393  0 819  HOH A O     1 ? 
HETATM 4657 O O     . HOH O 6 .   ? 2.087   3.545   -0.468  1.000 31.314  0 820  HOH A O     1 ? 
HETATM 4658 O O     . HOH O 6 .   ? -3.851  23.384  -21.448 1.000 30.356  0 821  HOH A O     1 ? 
HETATM 4659 O O     . HOH O 6 .   ? -11.783 -2.735  -54.298 1.000 24.304  0 822  HOH A O     1 ? 
HETATM 4660 O O     . HOH O 6 .   ? 7.858   14.802  -25.991 1.000 17.880  0 823  HOH A O     1 ? 
HETATM 4661 O O     . HOH O 6 .   ? -11.665 9.007   -59.296 1.000 32.914  0 824  HOH A O     1 ? 
HETATM 4662 O O     . HOH O 6 .   ? -20.859 -5.532  -36.176 1.000 53.155  0 825  HOH A O     1 ? 
HETATM 4663 O O     . HOH O 6 .   ? -5.717  -3.496  -47.419 1.000 32.514  0 826  HOH A O     1 ? 
HETATM 4664 O O     . HOH O 6 .   ? -8.793  14.453  -19.989 1.000 32.296  0 827  HOH A O     1 ? 
HETATM 4665 O O     . HOH O 6 .   ? -8.570  16.264  -33.673 1.000 16.437  0 828  HOH A O     1 ? 
HETATM 4666 O O     . HOH O 6 .   ? -4.170  24.651  -4.629  1.000 22.130  0 829  HOH A O     1 ? 
HETATM 4667 O O     . HOH O 6 .   ? -18.193 -1.183  -44.566 1.000 24.362  0 830  HOH A O     1 ? 
HETATM 4668 O O     . HOH O 6 .   ? -4.501  28.073  -10.184 1.000 19.831  0 831  HOH A O     1 ? 
HETATM 4669 O O     . HOH O 6 .   ? -10.177 -5.938  -22.804 1.000 28.623  0 832  HOH A O     1 ? 
HETATM 4670 O O     . HOH O 6 .   ? 1.730   21.773  -55.046 1.000 44.483  0 833  HOH A O     1 ? 
HETATM 4671 O O     . HOH O 6 .   ? 14.432  23.408  -19.012 1.000 27.704  0 834  HOH A O     1 ? 
HETATM 4672 O O     . HOH O 6 .   ? -28.265 5.176   -39.669 1.000 29.872  0 835  HOH A O     1 ? 
HETATM 4673 O O     . HOH O 6 .   ? 10.423  30.491  -13.065 1.000 40.438  0 836  HOH A O     1 ? 
HETATM 4674 O O     . HOH O 6 .   ? 12.083  -2.892  -18.841 1.000 41.722  0 837  HOH A O     1 ? 
HETATM 4675 O O     . HOH O 6 .   ? -18.605 1.291   -18.135 1.000 22.388  0 838  HOH A O     1 ? 
HETATM 4676 O O     . HOH O 6 .   ? 11.893  19.516  -6.023  1.000 27.737  0 839  HOH A O     1 ? 
HETATM 4677 O O     . HOH O 6 .   ? 16.620  11.363  -18.014 1.000 21.360  0 840  HOH A O     1 ? 
HETATM 4678 O O     . HOH O 6 .   ? -3.168  29.444  -12.186 1.000 21.251  0 841  HOH A O     1 ? 
HETATM 4679 O O     . HOH O 6 .   ? -30.482 14.340  -14.939 1.000 30.778  0 842  HOH A O     1 ? 
HETATM 4680 O O     . HOH O 6 .   ? -8.541  16.577  -30.977 1.000 18.355  0 843  HOH A O     1 ? 
HETATM 4681 O O     . HOH O 6 .   ? -16.103 5.873   -54.577 1.000 29.702  0 844  HOH A O     1 ? 
HETATM 4682 O O     . HOH O 6 .   ? -3.448  -2.102  -24.004 1.000 23.107  0 845  HOH A O     1 ? 
HETATM 4683 O O     . HOH O 6 .   ? -8.988  -2.340  -57.378 1.000 42.039  0 846  HOH A O     1 ? 
HETATM 4684 O O     . HOH O 6 .   ? 5.959   7.388   -4.571  1.000 23.930  0 847  HOH A O     1 ? 
HETATM 4685 O O     . HOH O 6 .   ? 7.757   9.532   -12.502 1.000 20.119  0 848  HOH A O     1 ? 
HETATM 4686 O O     . HOH O 6 .   ? 1.770   -7.239  -23.956 1.000 28.736  0 849  HOH A O     1 ? 
HETATM 4687 O O     . HOH O 6 .   ? -17.407 7.987   -55.305 1.000 35.321  0 850  HOH A O     1 ? 
HETATM 4688 O O     . HOH O 6 .   ? -16.345 -8.043  -26.614 1.000 46.146  0 851  HOH A O     1 ? 
HETATM 4689 O O     . HOH O 6 .   ? -16.548 9.749   -27.148 1.000 22.857  0 852  HOH A O     1 ? 
HETATM 4690 O O     . HOH O 6 .   ? -10.349 2.336   -0.556  1.000 27.905  0 853  HOH A O     1 ? 
HETATM 4691 O O     . HOH O 6 .   ? 7.599   28.395  -27.167 1.000 39.065  0 854  HOH A O     1 ? 
HETATM 4692 O O     . HOH O 6 .   ? 7.536   15.302  2.516   1.000 26.585  0 855  HOH A O     1 ? 
HETATM 4693 O O     . HOH O 6 .   ? -2.434  18.824  3.233   1.000 52.753  0 856  HOH A O     1 ? 
HETATM 4694 O O     . HOH O 6 .   ? -6.845  25.082  -5.067  1.000 21.693  0 857  HOH A O     1 ? 
HETATM 4695 O O     . HOH O 6 .   ? 5.490   23.622  -46.400 1.000 40.062  0 858  HOH A O     1 ? 
HETATM 4696 O O     . HOH O 6 .   ? 7.595   22.901  -13.197 1.000 20.951  0 859  HOH A O     1 ? 
HETATM 4697 O O     . HOH O 6 .   ? 8.593   8.834   -56.830 1.000 43.324  0 860  HOH A O     1 ? 
HETATM 4698 O O     . HOH O 6 .   ? -5.126  -3.380  -25.647 1.000 24.166  0 861  HOH A O     1 ? 
HETATM 4699 O O     . HOH O 6 .   ? -5.631  22.225  -39.608 1.000 33.692  0 862  HOH A O     1 ? 
HETATM 4700 O O     . HOH O 6 .   ? -16.063 22.692  -22.977 1.000 25.322  0 863  HOH A O     1 ? 
HETATM 4701 O O     . HOH O 6 .   ? -4.729  26.836  -14.643 1.000 23.550  0 864  HOH A O     1 ? 
HETATM 4702 O O     . HOH O 6 .   ? -20.592 24.596  -42.001 1.000 23.610  0 865  HOH A O     1 ? 
HETATM 4703 O O     . HOH O 6 .   ? -14.227 8.890   -17.159 1.000 19.523  0 866  HOH A O     1 ? 
HETATM 4704 O O     . HOH O 6 .   ? -0.188  27.831  -28.312 1.000 31.889  0 867  HOH A O     1 ? 
HETATM 4705 O O     . HOH O 6 .   ? -6.571  24.522  -39.761 1.000 47.191  0 868  HOH A O     1 ? 
HETATM 4706 O O     . HOH O 6 .   ? -5.497  34.639  -20.013 1.000 39.114  0 869  HOH A O     1 ? 
HETATM 4707 O O     . HOH O 6 .   ? -26.208 19.889  -36.478 1.000 33.912  0 870  HOH A O     1 ? 
HETATM 4708 O O     . HOH O 6 .   ? -9.711  12.704  2.054   1.000 34.715  0 871  HOH A O     1 ? 
HETATM 4709 O O     . HOH O 6 .   ? -19.463 6.789   -50.210 1.000 33.066  0 872  HOH A O     1 ? 
HETATM 4710 O O     . HOH O 6 .   ? -10.702 30.855  -42.042 1.000 24.911  0 873  HOH A O     1 ? 
HETATM 4711 O O     . HOH O 6 .   ? -1.942  -9.150  -23.235 1.000 35.832  0 874  HOH A O     1 ? 
HETATM 4712 O O     . HOH O 6 .   ? 1.740   -5.915  -12.822 1.000 36.238  0 875  HOH A O     1 ? 
HETATM 4713 O O     . HOH O 6 .   ? -9.791  39.495  -19.946 1.000 28.720  0 876  HOH A O     1 ? 
HETATM 4714 O O     . HOH O 6 .   ? -18.334 13.079  -22.119 1.000 22.894  0 877  HOH A O     1 ? 
HETATM 4715 O O     . HOH O 6 .   ? -5.281  26.635  -23.504 1.000 27.724  0 878  HOH A O     1 ? 
HETATM 4716 O O     . HOH O 6 .   ? 16.842  20.041  -22.611 1.000 23.515  0 879  HOH A O     1 ? 
HETATM 4717 O O     . HOH O 6 .   ? 1.472   9.180   -28.126 1.000 22.340  0 880  HOH A O     1 ? 
HETATM 4718 O O     . HOH O 6 .   ? 4.404   25.402  -36.769 1.000 40.744  0 881  HOH A O     1 ? 
HETATM 4719 O O     . HOH O 6 .   ? -17.444 35.522  -11.704 1.000 27.878  0 882  HOH A O     1 ? 
HETATM 4720 O O     . HOH O 6 .   ? -18.162 35.133  -9.100  1.000 30.964  0 883  HOH A O     1 ? 
HETATM 4721 O O     . HOH O 6 .   ? 3.311   18.365  -15.482 1.000 23.319  0 884  HOH A O     1 ? 
HETATM 4722 O O     . HOH O 6 .   ? -16.006 10.749  -59.258 1.000 45.832  0 885  HOH A O     1 ? 
HETATM 4723 O O     . HOH O 6 .   ? -13.285 -1.088  -10.824 1.000 37.989  0 886  HOH A O     1 ? 
HETATM 4724 O O     . HOH O 6 .   ? -6.393  17.880  -34.242 1.000 21.794  0 887  HOH A O     1 ? 
HETATM 4725 O O     . HOH O 6 .   ? 9.405   4.041   -11.735 1.000 24.495  0 888  HOH A O     1 ? 
HETATM 4726 O O     . HOH O 6 .   ? -6.240  8.371   -24.452 1.000 14.137  0 889  HOH A O     1 ? 
HETATM 4727 O O     . HOH O 6 .   ? -17.868 29.307  -41.527 1.000 31.001  0 890  HOH A O     1 ? 
HETATM 4728 O O     . HOH O 6 .   ? -22.992 29.270  -52.024 1.000 47.882  0 891  HOH A O     1 ? 
HETATM 4729 O O     . HOH O 6 .   ? 2.078   22.875  -45.570 1.000 23.031  0 892  HOH A O     1 ? 
HETATM 4730 O O     . HOH O 6 .   ? -22.315 26.062  -24.773 1.000 24.619  0 893  HOH A O     1 ? 
HETATM 4731 O O     . HOH O 6 .   ? -28.242 11.395  -43.422 1.000 37.581  0 894  HOH A O     1 ? 
HETATM 4732 O O     . HOH O 6 .   ? -0.814  31.824  -30.779 1.000 42.060  0 895  HOH A O     1 ? 
HETATM 4733 O O     . HOH O 6 .   ? -0.727  -0.839  -5.721  1.000 30.101  0 896  HOH A O     1 ? 
HETATM 4734 O O     . HOH O 6 .   ? -10.450 34.401  -1.600  1.000 30.146  0 897  HOH A O     1 ? 
HETATM 4735 O O     . HOH O 6 .   ? 23.616  22.818  -20.600 1.000 40.360  0 898  HOH A O     1 ? 
HETATM 4736 O O     . HOH O 6 .   ? -24.481 11.651  -22.126 1.000 29.242  0 899  HOH A O     1 ? 
HETATM 4737 O O     . HOH O 6 .   ? -1.715  20.923  -18.473 1.000 36.404  0 900  HOH A O     1 ? 
HETATM 4738 O O     . HOH O 6 .   ? 8.614   17.358  7.351   1.000 28.368  0 901  HOH A O     1 ? 
HETATM 4739 O O     . HOH O 6 .   ? -27.071 -1.773  -35.005 1.000 34.387  0 902  HOH A O     1 ? 
HETATM 4740 O O     . HOH O 6 .   ? 12.889  20.177  -8.817  1.000 38.168  0 903  HOH A O     1 ? 
HETATM 4741 O O     . HOH O 6 .   ? -23.336 9.325   -48.230 1.000 38.605  0 904  HOH A O     1 ? 
HETATM 4742 O O     . HOH O 6 .   ? 2.537   2.429   -55.733 1.000 35.678  0 905  HOH A O     1 ? 
HETATM 4743 O O     . HOH O 6 .   ? -24.295 13.100  -30.853 1.000 28.881  0 906  HOH A O     1 ? 
HETATM 4744 O O     . HOH O 6 .   ? -6.089  7.912   4.947   1.000 39.952  0 907  HOH A O     1 ? 
HETATM 4745 O O     . HOH O 6 .   ? -20.030 15.554  -22.543 1.000 24.671  0 908  HOH A O     1 ? 
HETATM 4746 O O     . HOH O 6 .   ? -5.261  19.737  -29.893 1.000 27.413  0 909  HOH A O     1 ? 
HETATM 4747 O O     . HOH O 6 .   ? -16.342 29.790  -34.389 1.000 22.440  0 910  HOH A O     1 ? 
HETATM 4748 O O     . HOH O 6 .   ? 23.999  13.223  -17.390 1.000 32.771  0 911  HOH A O     1 ? 
HETATM 4749 O O     . HOH O 6 .   ? -10.301 31.870  -33.338 1.000 27.109  0 912  HOH A O     1 ? 
HETATM 4750 O O     . HOH O 6 .   ? 15.454  7.036   -12.701 1.000 30.172  0 913  HOH A O     1 ? 
HETATM 4751 O O     . HOH O 6 .   ? 9.712   10.403  -32.977 1.000 20.751  0 914  HOH A O     1 ? 
HETATM 4752 O O     . HOH O 6 .   ? 1.095   -6.502  -43.910 1.000 28.404  0 915  HOH A O     1 ? 
HETATM 4753 O O     . HOH O 6 .   ? -18.417 22.396  -54.105 1.000 38.890  0 916  HOH A O     1 ? 
HETATM 4754 O O     . HOH O 6 .   ? 3.062   23.652  -53.494 1.000 27.962  0 917  HOH A O     1 ? 
HETATM 4755 O O     . HOH O 6 .   ? -19.999 15.142  -25.530 1.000 24.078  0 918  HOH A O     1 ? 
HETATM 4756 O O     . HOH O 6 .   ? 9.776   2.790   -21.468 1.000 22.735  0 919  HOH A O     1 ? 
HETATM 4757 O O     . HOH O 6 .   ? -10.426 -3.765  -21.117 1.000 23.719  0 920  HOH A O     1 ? 
HETATM 4758 O O     . HOH O 6 .   ? -3.650  5.859   -18.298 1.000 20.974  0 921  HOH A O     1 ? 
HETATM 4759 O O     . HOH O 6 .   ? -10.188 1.435   -3.587  1.000 29.757  0 922  HOH A O     1 ? 
HETATM 4760 O O     . HOH O 6 .   ? -2.144  28.047  -14.299 1.000 20.760  0 923  HOH A O     1 ? 
HETATM 4761 O O     . HOH O 6 .   ? -2.588  -9.237  -49.865 1.000 40.489  0 924  HOH A O     1 ? 
HETATM 4762 O O     . HOH O 6 .   ? -18.351 1.529   -45.089 1.000 27.915  0 925  HOH A O     1 ? 
HETATM 4763 O O     . HOH O 6 .   ? -27.181 10.077  -45.154 1.000 40.468  0 926  HOH A O     1 ? 
HETATM 4764 O O     . HOH O 6 .   ? -5.672  2.568   -13.301 1.000 20.775  0 927  HOH A O     1 ? 
HETATM 4765 O O     . HOH O 6 .   ? -7.759  23.766  -45.780 1.000 47.383  0 928  HOH A O     1 ? 
HETATM 4766 O O     . HOH O 6 .   ? 6.299   -1.527  -30.709 1.000 34.923  0 929  HOH A O     1 ? 
HETATM 4767 O O     . HOH O 6 .   ? -20.636 17.884  -36.022 1.000 18.620  0 930  HOH A O     1 ? 
HETATM 4768 O O     . HOH O 6 .   ? -25.195 8.333   -60.403 1.000 35.606  0 931  HOH A O     1 ? 
HETATM 4769 O O     . HOH O 6 .   ? 4.969   17.152  -6.590  1.000 17.812  0 932  HOH A O     1 ? 
HETATM 4770 O O     . HOH O 6 .   ? 13.698  25.794  -5.236  1.000 33.383  0 933  HOH A O     1 ? 
HETATM 4771 O O     . HOH O 6 .   ? 0.186   28.214  -36.125 1.000 43.181  0 934  HOH A O     1 ? 
HETATM 4772 O O     . HOH O 6 .   ? -8.834  9.432   -0.552  1.000 21.921  0 935  HOH A O     1 ? 
HETATM 4773 O O     . HOH O 6 .   ? -3.404  2.016   -10.824 1.000 16.117  0 936  HOH A O     1 ? 
HETATM 4774 O O     . HOH O 6 .   ? -22.617 23.948  -31.837 1.000 34.054  0 937  HOH A O     1 ? 
HETATM 4775 O O     . HOH O 6 .   ? -17.099 22.499  -25.298 1.000 34.214  0 938  HOH A O     1 ? 
HETATM 4776 O O     . HOH O 6 .   ? -20.882 33.048  -17.450 1.000 34.202  0 939  HOH A O     1 ? 
HETATM 4777 O O     . HOH O 6 .   ? 4.276   14.398  -13.278 1.000 21.708  0 940  HOH A O     1 ? 
HETATM 4778 O O     . HOH O 6 .   ? -17.966 2.750   -11.366 1.000 39.509  0 941  HOH A O     1 ? 
HETATM 4779 O O     . HOH O 6 .   ? -23.105 26.093  -30.700 1.000 43.594  0 942  HOH A O     1 ? 
HETATM 4780 O O     . HOH O 6 .   ? -29.604 11.957  -17.840 1.000 43.575  0 943  HOH A O     1 ? 
HETATM 4781 O O     . HOH O 6 .   ? -8.494  5.871   -12.771 1.000 18.993  0 944  HOH A O     1 ? 
HETATM 4782 O O     . HOH O 6 .   ? -4.085  37.480  -42.299 1.000 28.980  0 945  HOH A O     1 ? 
HETATM 4783 O O     . HOH O 6 .   ? -16.888 -7.923  -35.711 1.000 44.276  0 946  HOH A O     1 ? 
HETATM 4784 O O     . HOH O 6 .   ? -5.909  3.927   -58.187 1.000 37.679  0 947  HOH A O     1 ? 
HETATM 4785 O O     . HOH O 6 .   ? -27.397 19.806  -50.431 1.000 35.054  0 948  HOH A O     1 ? 
HETATM 4786 O O     . HOH O 6 .   ? 17.288  27.948  -17.777 1.000 36.959  0 949  HOH A O     1 ? 
HETATM 4787 O O     . HOH O 6 .   ? -30.382 10.082  -0.860  1.000 54.947  0 950  HOH A O     1 ? 
HETATM 4788 O O     . HOH O 6 .   ? -25.752 10.527  -47.580 1.000 32.366  0 951  HOH A O     1 ? 
HETATM 4789 O O     . HOH O 6 .   ? -7.482  22.503  -42.943 1.000 34.928  0 952  HOH A O     1 ? 
HETATM 4790 O O     . HOH O 6 .   ? 3.063   32.952  -14.034 1.000 29.440  0 953  HOH A O     1 ? 
HETATM 4791 O O     . HOH O 6 .   ? -26.073 26.826  -18.576 1.000 27.353  0 954  HOH A O     1 ? 
HETATM 4792 O O     . HOH O 6 .   ? -24.708 3.774   -17.260 1.000 36.110  0 955  HOH A O     1 ? 
HETATM 4793 O O     . HOH O 6 .   ? -13.909 1.825   1.623   1.000 45.743  0 956  HOH A O     1 ? 
HETATM 4794 O O     . HOH O 6 .   ? -24.956 12.740  -33.199 1.000 36.782  0 957  HOH A O     1 ? 
HETATM 4795 O O     . HOH O 6 .   ? -15.855 -7.659  -47.620 1.000 39.830  0 958  HOH A O     1 ? 
HETATM 4796 O O     . HOH O 6 .   ? -9.706  -1.081  -8.476  1.000 25.798  0 959  HOH A O     1 ? 
HETATM 4797 O O     . HOH O 6 .   ? -9.494  26.518  -50.975 1.000 34.196  0 960  HOH A O     1 ? 
HETATM 4798 O O     . HOH O 6 .   ? -0.308  -4.396  -36.156 1.000 39.851  0 961  HOH A O     1 ? 
HETATM 4799 O O     . HOH O 6 .   ? -1.736  19.036  -60.437 1.000 39.435  0 962  HOH A O     1 ? 
HETATM 4800 O O     . HOH O 6 .   ? -15.270 21.635  -56.742 1.000 32.562  0 963  HOH A O     1 ? 
HETATM 4801 O O     . HOH O 6 .   ? -9.778  9.613   2.806   1.000 24.590  0 964  HOH A O     1 ? 
HETATM 4802 O O     . HOH O 6 .   ? -1.250  30.138  -29.043 1.000 29.992  0 965  HOH A O     1 ? 
HETATM 4803 O O     . HOH O 6 .   ? -1.827  21.323  -37.661 1.000 29.662  0 966  HOH A O     1 ? 
HETATM 4804 O O     . HOH O 6 .   ? -8.869  -8.281  -22.276 1.000 36.775  0 967  HOH A O     1 ? 
HETATM 4805 O O     . HOH O 6 .   ? 1.786   -5.506  -32.229 1.000 40.104  0 968  HOH A O     1 ? 
HETATM 4806 O O     . HOH O 6 .   ? 8.667   27.532  -34.501 1.000 36.733  0 969  HOH A O     1 ? 
HETATM 4807 O O     . HOH O 6 .   ? 1.216   29.777  -46.024 1.000 37.798  0 970  HOH A O     1 ? 
HETATM 4808 O O     . HOH O 6 .   ? 6.648   17.897  -18.154 1.000 36.776  0 971  HOH A O     1 ? 
HETATM 4809 O O     . HOH O 6 .   ? -13.175 35.522  -47.829 1.000 36.533  0 972  HOH A O     1 ? 
HETATM 4810 O O     . HOH O 6 .   ? -17.357 8.711   -8.225  1.000 27.454  0 973  HOH A O     1 ? 
HETATM 4811 O O     . HOH O 6 .   ? 4.158   12.771  3.457   1.000 41.095  0 974  HOH A O     1 ? 
HETATM 4812 O O     . HOH O 6 .   ? -0.874  8.731   -62.293 1.000 33.433  0 975  HOH A O     1 ? 
HETATM 4813 O O     . HOH O 6 .   ? 6.243   5.305   -47.652 1.000 37.046  0 976  HOH A O     1 ? 
HETATM 4814 O O     . HOH O 6 .   ? -2.165  27.268  -58.405 1.000 34.341  0 977  HOH A O     1 ? 
HETATM 4815 O O     . HOH O 6 .   ? 13.843  2.452   -28.962 1.000 45.718  0 978  HOH A O     1 ? 
HETATM 4816 O O     . HOH O 6 .   ? -9.398  -4.480  -14.446 1.000 34.839  0 979  HOH A O     1 ? 
HETATM 4817 O O     . HOH O 6 .   ? -19.733 4.589   -11.899 1.000 24.607  0 980  HOH A O     1 ? 
HETATM 4818 O O     . HOH O 6 .   ? 10.067  0.013   -21.792 1.000 33.048  0 981  HOH A O     1 ? 
HETATM 4819 O O     . HOH O 6 .   ? -8.130  38.555  -17.773 1.000 36.322  0 982  HOH A O     1 ? 
HETATM 4820 O O     . HOH O 6 .   ? -25.678 8.676   -19.881 1.000 38.715  0 983  HOH A O     1 ? 
HETATM 4821 O O     . HOH O 6 .   ? 3.577   2.252   -2.542  1.000 36.096  0 984  HOH A O     1 ? 
HETATM 4822 O O     . HOH O 6 .   ? 6.742   7.673   -48.922 1.000 25.955  0 985  HOH A O     1 ? 
HETATM 4823 O O     . HOH O 6 .   ? -4.929  32.326  -21.126 1.000 36.934  0 986  HOH A O     1 ? 
HETATM 4824 O O     . HOH O 6 .   ? -26.096 6.519   -23.990 1.000 44.352  0 987  HOH A O     1 ? 
HETATM 4825 O O     . HOH O 6 .   ? -11.723 -5.045  -15.354 1.000 43.239  0 988  HOH A O     1 ? 
HETATM 4826 O O     . HOH O 6 .   ? 8.438   3.142   -18.951 1.000 24.383  0 989  HOH A O     1 ? 
HETATM 4827 O O     . HOH O 6 .   ? 5.554   5.326   -19.037 1.000 18.615  0 990  HOH A O     1 ? 
HETATM 4828 O O     . HOH O 6 .   ? 6.985   6.292   -8.636  1.000 27.015  0 991  HOH A O     1 ? 
HETATM 4829 O O     . HOH O 6 .   ? -19.979 -3.159  -19.663 1.000 36.090  0 992  HOH A O     1 ? 
HETATM 4830 O O     . HOH O 6 .   ? -25.529 16.623  -46.032 1.000 37.165  0 993  HOH A O     1 ? 
HETATM 4831 O O     . HOH O 6 .   ? -17.847 31.990  -34.331 1.000 34.457  0 994  HOH A O     1 ? 
HETATM 4832 O O     . HOH O 6 .   ? 1.451   32.864  -2.922  1.000 52.150  0 995  HOH A O     1 ? 
HETATM 4833 O O     . HOH O 6 .   ? 12.754  21.075  -20.369 1.000 37.791  0 996  HOH A O     1 ? 
HETATM 4834 O O     . HOH O 6 .   ? 5.956   27.867  -35.191 1.000 33.232  0 997  HOH A O     1 ? 
HETATM 4835 O O     . HOH O 6 .   ? 3.548   -5.451  -43.658 1.000 31.134  0 998  HOH A O     1 ? 
HETATM 4836 O O     . HOH O 6 .   ? -32.389 15.729  -37.628 1.000 38.195  0 999  HOH A O     1 ? 
HETATM 4837 O O     . HOH O 6 .   ? -17.828 -8.237  -39.081 1.000 46.762  0 1000 HOH A O     1 ? 
HETATM 4838 O O     . HOH O 6 .   ? -3.997  28.228  -39.984 1.000 37.057  0 1001 HOH A O     1 ? 
HETATM 4839 O O     . HOH O 6 .   ? -15.867 28.439  -53.036 1.000 39.027  0 1002 HOH A O     1 ? 
HETATM 4840 O O     . HOH O 6 .   ? -30.774 18.642  -19.931 1.000 42.549  0 1003 HOH A O     1 ? 
HETATM 4841 O O     . HOH O 6 .   ? 9.781   26.960  5.586   1.000 42.423  0 1004 HOH A O     1 ? 
HETATM 4842 O O     . HOH O 6 .   ? -14.728 37.122  -6.217  1.000 50.999  0 1005 HOH A O     1 ? 
HETATM 4843 O O     . HOH O 6 .   ? -20.578 35.899  -12.138 1.000 45.192  0 1006 HOH A O     1 ? 
HETATM 4844 O O     . HOH O 6 .   ? 4.738   9.349   -13.865 1.000 22.797  0 1007 HOH A O     1 ? 
HETATM 4845 O O     . HOH O 6 .   ? 1.480   4.422   -56.441 1.000 46.407  0 1008 HOH A O     1 ? 
HETATM 4846 O O     . HOH O 6 .   ? -24.054 4.089   -42.080 1.000 35.644  0 1009 HOH A O     1 ? 
HETATM 4847 O O     . HOH O 6 .   ? -24.302 4.946   -22.519 1.000 43.140  0 1010 HOH A O     1 ? 
HETATM 4848 O O     . HOH O 6 .   ? -10.425 -7.370  -35.500 1.000 35.158  0 1011 HOH A O     1 ? 
HETATM 4849 O O     . HOH O 6 .   ? -16.210 5.439   -26.949 1.000 105.337 0 1012 HOH A O     1 ? 
HETATM 4850 O O     . HOH O 6 .   ? -18.226 14.437  -67.834 1.000 54.352  0 1013 HOH A O     1 ? 
HETATM 4851 O O     . HOH O 6 .   ? -9.034  13.601  4.481   1.000 43.379  0 1014 HOH A O     1 ? 
HETATM 4852 O O     . HOH O 6 .   ? -2.590  7.980   -46.330 1.000 86.602  0 1015 HOH A O     1 ? 
HETATM 4853 O O     . HOH O 6 .   ? -18.542 31.573  -41.136 1.000 46.672  0 1016 HOH A O     1 ? 
HETATM 4854 O O     . HOH O 6 .   ? 12.152  13.872  -45.154 1.000 36.401  0 1017 HOH A O     1 ? 
HETATM 4855 O O     . HOH O 6 .   ? 17.675  7.702   -12.746 1.000 45.557  0 1018 HOH A O     1 ? 
HETATM 4856 O O     . HOH O 6 .   ? 5.836   0.925   -31.368 1.000 47.172  0 1019 HOH A O     1 ? 
HETATM 4857 O O     . HOH O 6 .   ? -1.859  21.856  -39.799 1.000 39.270  0 1020 HOH A O     1 ? 
HETATM 4858 O O     . HOH O 6 .   ? -22.483 -5.215  -34.301 1.000 40.165  0 1021 HOH A O     1 ? 
HETATM 4859 O O     . HOH O 6 .   ? 10.083  20.712  -19.217 1.000 32.172  0 1022 HOH A O     1 ? 
HETATM 4860 O O     . HOH O 6 .   ? -2.728  33.157  -32.245 1.000 32.759  0 1023 HOH A O     1 ? 
HETATM 4861 O O     . HOH O 6 .   ? -10.658 -0.272  0.678   1.000 47.257  0 1024 HOH A O     1 ? 
HETATM 4862 O O     . HOH O 6 .   ? -8.542  -1.515  -6.136  1.000 49.085  0 1025 HOH A O     1 ? 
HETATM 4863 O O     . HOH O 6 .   ? -6.687  -3.475  -54.377 1.000 62.285  0 1026 HOH A O     1 ? 
HETATM 4864 O O     . HOH O 6 .   ? 3.373   4.574   1.203   1.000 51.200  0 1027 HOH A O     1 ? 
HETATM 4865 O O     . HOH O 6 .   ? 7.678   3.896   -9.839  1.000 31.917  0 1028 HOH A O     1 ? 
HETATM 4866 O O     . HOH O 6 .   ? -18.080 5.084   -52.798 1.000 31.157  0 1029 HOH A O     1 ? 
HETATM 4867 O O     . HOH O 6 .   ? 10.243  29.148  -1.916  1.000 46.883  0 1030 HOH A O     1 ? 
HETATM 4868 O O     . HOH O 6 .   ? 6.431   5.271   -6.000  1.000 41.213  0 1031 HOH A O     1 ? 
HETATM 4869 O O     . HOH O 6 .   ? -19.577 -2.375  -46.351 1.000 40.147  0 1032 HOH A O     1 ? 
HETATM 4870 O O     . HOH O 6 .   ? -2.814  30.253  -21.101 1.000 30.577  0 1033 HOH A O     1 ? 
HETATM 4871 O O     . HOH O 6 .   ? -18.792 31.389  -24.368 1.000 42.562  0 1034 HOH A O     1 ? 
HETATM 4872 O O     . HOH O 6 .   ? -14.244 14.238  -62.840 1.000 43.323  0 1035 HOH A O     1 ? 
HETATM 4873 O O     . HOH O 6 .   ? -27.303 11.023  -13.011 1.000 51.081  0 1036 HOH A O     1 ? 
HETATM 4874 O O     . HOH O 6 .   ? 16.433  19.979  -25.203 1.000 31.091  0 1037 HOH A O     1 ? 
HETATM 4875 O O     . HOH O 6 .   ? -26.013 14.268  -29.251 1.000 39.032  0 1038 HOH A O     1 ? 
HETATM 4876 O O     . HOH O 6 .   ? 4.028   -4.120  -32.884 1.000 46.680  0 1039 HOH A O     1 ? 
HETATM 4877 O O     . HOH O 6 .   ? -6.472  18.137  -31.431 1.000 31.166  0 1040 HOH A O     1 ? 
HETATM 4878 O O     . HOH O 6 .   ? -21.802 16.195  -27.273 1.000 41.708  0 1041 HOH A O     1 ? 
HETATM 4879 O O     . HOH O 6 .   ? -0.166  -6.055  -34.139 1.000 37.364  0 1042 HOH A O     1 ? 
HETATM 4880 O O     . HOH O 6 .   ? -26.971 16.602  -43.585 1.000 38.973  0 1043 HOH A O     1 ? 
HETATM 4881 O O     . HOH O 6 .   ? -8.303  38.947  -21.656 1.000 36.462  0 1044 HOH A O     1 ? 
HETATM 4882 O O     . HOH O 6 .   ? -20.963 0.030   -40.704 1.000 43.656  0 1045 HOH A O     1 ? 
HETATM 4883 O O     . HOH O 6 .   ? 11.976  19.831  -41.277 1.000 39.889  0 1046 HOH A O     1 ? 
HETATM 4884 O O     . HOH O 6 .   ? -16.306 4.315   -56.990 1.000 40.715  0 1047 HOH A O     1 ? 
HETATM 4885 O O     . HOH O 6 .   ? 18.345  18.292  -1.917  1.000 40.770  0 1048 HOH A O     1 ? 
HETATM 4886 O O     . HOH O 6 .   ? -3.523  -6.886  -36.186 1.000 35.547  0 1049 HOH A O     1 ? 
HETATM 4887 O O     . HOH O 6 .   ? -23.941 -4.504  -26.261 1.000 37.219  0 1050 HOH A O     1 ? 
HETATM 4888 O O     . HOH O 6 .   ? -24.015 13.295  -25.791 1.000 42.904  0 1051 HOH A O     1 ? 
HETATM 4889 O O     . HOH O 6 .   ? -5.357  -8.047  -52.596 1.000 48.623  0 1052 HOH A O     1 ? 
HETATM 4890 O O     . HOH O 6 .   ? 8.937   5.835   -52.950 1.000 45.749  0 1053 HOH A O     1 ? 
HETATM 4891 O O     . HOH O 6 .   ? -2.183  25.480  -20.891 1.000 32.091  0 1054 HOH A O     1 ? 
HETATM 4892 O O     . HOH O 6 .   ? 12.223  16.274  -44.144 1.000 40.561  0 1055 HOH A O     1 ? 
HETATM 4893 O O     . HOH O 6 .   ? 6.266   -3.530  -36.836 1.000 46.225  0 1056 HOH A O     1 ? 
HETATM 4894 O O     . HOH O 6 .   ? -31.362 4.893   -36.114 1.000 47.511  0 1057 HOH A O     1 ? 
HETATM 4895 O O     . HOH O 6 .   ? -7.979  -0.647  -3.579  1.000 44.297  0 1058 HOH A O     1 ? 
HETATM 4896 O O     . HOH O 6 .   ? -2.948  27.456  -22.263 1.000 31.621  0 1059 HOH A O     1 ? 
HETATM 4897 O O     . HOH O 6 .   ? -15.826 11.980  -4.547  1.000 45.698  0 1060 HOH A O     1 ? 
HETATM 4898 O O     . HOH O 6 .   ? -18.977 6.457   -9.320  1.000 31.394  0 1061 HOH A O     1 ? 
HETATM 4899 O O     . HOH O 6 .   ? -11.972 39.160  -31.693 1.000 36.369  0 1062 HOH A O     1 ? 
HETATM 4900 O O     . HOH O 6 .   ? -6.299  -3.986  -6.271  1.000 42.486  0 1063 HOH A O     1 ? 
HETATM 4901 O O     . HOH O 6 .   ? -15.788 7.685   -6.250  1.000 31.845  0 1064 HOH A O     1 ? 
HETATM 4902 O O     . HOH O 6 .   ? -0.545  27.963  -23.908 1.000 34.360  0 1065 HOH A O     1 ? 
HETATM 4903 O O     . HOH O 6 .   ? -16.575 4.894   -5.943  1.000 47.036  0 1066 HOH A O     1 ? 
# 
