data_9AS4
# 
_entry.id   9AS4 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9AS4         pdb_00009as4 10.2210/pdb9as4/pdb 
WWPDB D_1000281843 ?            ?                   
EMDB  EMD-43804    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-04-02 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9AS4 
_pdbx_database_status.recvd_initial_deposition_date   2024-02-24 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
;Global reconstruction of 5-HT2AR bound to LSD in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
;
_pdbx_database_related.db_id          EMD-43804 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 4 
_pdbx_contact_author.email              bryan_roth@med.unc.edu 
_pdbx_contact_author.name_first         Bryan 
_pdbx_contact_author.name_last          Roth 
_pdbx_contact_author.name_mi            L. 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-0561-6520 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Gumpper, R.H.' 1 ? 
'Fay, J.F.'     2 ? 
'Roth, B.L.'    3 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            16 
_citation.language                  ? 
_citation.page_first                2734 
_citation.page_last                 2734 
_citation.title                     'The structural diversity of psychedelic drug actions revealed.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-025-57956-7 
_citation.pdbx_database_id_PubMed   40108183 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Gumpper, R.H.'  1  0000-0003-1309-3069 
primary 'Jain, M.K.'     2  0000-0001-8173-3326 
primary 'Kim, K.'        3  ?                   
primary 'Sun, R.'        4  ?                   
primary 'Sun, N.'        5  ?                   
primary 'Xu, Z.'         6  ?                   
primary 'DiBerto, J.F.'  7  ?                   
primary 'Krumm, B.E.'    8  0000-0001-6039-4767 
primary 'Kapolka, N.J.'  9  ?                   
primary 'Kaniskan, H.U.' 10 0000-0001-5327-832X 
primary 'Nichols, D.E.'  11 ?                   
primary 'Jin, J.'        12 0000-0002-2387-3862 
primary 'Fay, J.F.'      13 0000-0003-1822-2384 
primary 'Roth, B.L.'     14 0000-0002-0561-6520 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man '5-hydroxytryptamine receptor 2A'                                    52648.945 1 ? ? ? ? 
2 polymer     man 'G subunit q (Gi2-mini-Gq chimeric)'                                 28084.832 1 ? ? ? ? 
3 polymer     man 'Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1'   39418.086 1 ? ? ? ? 
4 polymer     man 'Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2'  7861.143  1 ? ? ? ? 
5 polymer     man 'single chain Fab (svFv16)'                                          28668.922 1 ? ? ? ? 
6 non-polymer syn '(8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide' 323.432   1 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 '5-HT-2,5-HT-2A,Serotonin receptor 2A' 
3 'Transducin beta chain 1'              
4 'G gamma-I'                            
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALL
TAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFST
ASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQK
ACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYK
ENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
;
;MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALL
TAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFST
ASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQK
ACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYK
ENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
;
A ? 
2 'polypeptide(L)' no no 
;MGSTVSAEDKAAAERSKMIDKNLREDGEKARRTLRLLLLGADNSGKSTIVKQMRILHGGSGGSGGTSGIFETKFQVDKVN
FHMFDVGGQRDERRKWIQCFNDVTAIIFVVDSSDYNRLQEALNDFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKI
EDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRKEFVDISTASGDGRHICYPHFTCAVDTENARRIFNDCKDIILQMNL
REYNLV
;
;MGSTVSAEDKAAAERSKMIDKNLREDGEKARRTLRLLLLGADNSGKSTIVKQMRILHGGSGGSGGTSGIFETKFQVDKVN
FHMFDVGGQRDERRKWIQCFNDVTAIIFVVDSSDYNRLQEALNDFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKI
EDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRKEFVDISTASGDGRHICYPHFTCAVDTENARRIFNDCKDIILQMNL
REYNLV
;
B ? 
3 'polypeptide(L)' no no 
;MHHHHHHLEVLFQGPGSSGSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMH
WGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGH
TGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTF
TGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKA
DRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN
;
;MHHHHHHLEVLFQGPGSSGSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMH
WGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGH
TGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTF
TGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKA
DRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN
;
C ? 
4 'polypeptide(L)' no no MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 
MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL D ? 
5 'polypeptide(L)' no no 
;DVQLVESGGGLVQPGGSRKLSCSASGFAFSSFGMHWVRQAPEKGLEWVAYISSGSGTIYYADTVKGRFTISRDDPKNTLF
LQMTSLRSEDTAMYYCVRSIYYYGSSPFDFWGQGTTLTVSSGGGGSGGGGSGGGGSDIVMTQATSSVPVTPGESVSISCR
SSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDRFSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTFG
AGTKLELKAAALEVLFQGPHHHHHHHH
;
;DVQLVESGGGLVQPGGSRKLSCSASGFAFSSFGMHWVRQAPEKGLEWVAYISSGSGTIYYADTVKGRFTISRDDPKNTLF
LQMTSLRSEDTAMYYCVRSIYYYGSSPFDFWGQGTTLTVSSGGGGSGGGGSGGGGSDIVMTQATSSVPVTPGESVSISCR
SSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDRFSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTFG
AGTKLELKAAALEVLFQGPHHHHHHHH
;
E ? 
# 
_pdbx_entity_nonpoly.entity_id   6 
_pdbx_entity_nonpoly.name        '(8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide' 
_pdbx_entity_nonpoly.comp_id     7LD 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ASP n 
1 3   ILE n 
1 4   LEU n 
1 5   CYS n 
1 6   GLU n 
1 7   GLU n 
1 8   ASN n 
1 9   THR n 
1 10  SER n 
1 11  LEU n 
1 12  SER n 
1 13  SER n 
1 14  THR n 
1 15  THR n 
1 16  ASN n 
1 17  SER n 
1 18  LEU n 
1 19  MET n 
1 20  GLN n 
1 21  LEU n 
1 22  ASN n 
1 23  ASP n 
1 24  ASP n 
1 25  THR n 
1 26  ARG n 
1 27  LEU n 
1 28  TYR n 
1 29  SER n 
1 30  ASN n 
1 31  ASP n 
1 32  PHE n 
1 33  ASN n 
1 34  SER n 
1 35  GLY n 
1 36  GLU n 
1 37  ALA n 
1 38  ASN n 
1 39  THR n 
1 40  SER n 
1 41  ASP n 
1 42  ALA n 
1 43  PHE n 
1 44  ASN n 
1 45  TRP n 
1 46  THR n 
1 47  VAL n 
1 48  ASP n 
1 49  SER n 
1 50  GLU n 
1 51  ASN n 
1 52  ARG n 
1 53  THR n 
1 54  ASN n 
1 55  LEU n 
1 56  SER n 
1 57  CYS n 
1 58  GLU n 
1 59  GLY n 
1 60  CYS n 
1 61  LEU n 
1 62  SER n 
1 63  PRO n 
1 64  SER n 
1 65  CYS n 
1 66  LEU n 
1 67  SER n 
1 68  LEU n 
1 69  LEU n 
1 70  HIS n 
1 71  LEU n 
1 72  GLN n 
1 73  GLU n 
1 74  LYS n 
1 75  ASN n 
1 76  TRP n 
1 77  SER n 
1 78  ALA n 
1 79  LEU n 
1 80  LEU n 
1 81  THR n 
1 82  ALA n 
1 83  VAL n 
1 84  VAL n 
1 85  ILE n 
1 86  ILE n 
1 87  LEU n 
1 88  THR n 
1 89  ILE n 
1 90  ALA n 
1 91  GLY n 
1 92  ASN n 
1 93  ILE n 
1 94  LEU n 
1 95  VAL n 
1 96  ILE n 
1 97  MET n 
1 98  ALA n 
1 99  VAL n 
1 100 SER n 
1 101 LEU n 
1 102 GLU n 
1 103 LYS n 
1 104 LYS n 
1 105 LEU n 
1 106 GLN n 
1 107 ASN n 
1 108 ALA n 
1 109 THR n 
1 110 ASN n 
1 111 TYR n 
1 112 PHE n 
1 113 LEU n 
1 114 MET n 
1 115 SER n 
1 116 LEU n 
1 117 ALA n 
1 118 ILE n 
1 119 ALA n 
1 120 ASP n 
1 121 MET n 
1 122 LEU n 
1 123 LEU n 
1 124 GLY n 
1 125 PHE n 
1 126 LEU n 
1 127 VAL n 
1 128 MET n 
1 129 PRO n 
1 130 VAL n 
1 131 SER n 
1 132 MET n 
1 133 LEU n 
1 134 THR n 
1 135 ILE n 
1 136 LEU n 
1 137 TYR n 
1 138 GLY n 
1 139 TYR n 
1 140 ARG n 
1 141 TRP n 
1 142 PRO n 
1 143 LEU n 
1 144 PRO n 
1 145 SER n 
1 146 LYS n 
1 147 LEU n 
1 148 CYS n 
1 149 ALA n 
1 150 VAL n 
1 151 TRP n 
1 152 ILE n 
1 153 TYR n 
1 154 LEU n 
1 155 ASP n 
1 156 VAL n 
1 157 LEU n 
1 158 PHE n 
1 159 SER n 
1 160 THR n 
1 161 ALA n 
1 162 SER n 
1 163 ILE n 
1 164 MET n 
1 165 HIS n 
1 166 LEU n 
1 167 CYS n 
1 168 ALA n 
1 169 ILE n 
1 170 SER n 
1 171 LEU n 
1 172 ASP n 
1 173 ARG n 
1 174 TYR n 
1 175 VAL n 
1 176 ALA n 
1 177 ILE n 
1 178 GLN n 
1 179 ASN n 
1 180 PRO n 
1 181 ILE n 
1 182 HIS n 
1 183 HIS n 
1 184 SER n 
1 185 ARG n 
1 186 PHE n 
1 187 ASN n 
1 188 SER n 
1 189 ARG n 
1 190 THR n 
1 191 LYS n 
1 192 ALA n 
1 193 PHE n 
1 194 LEU n 
1 195 LYS n 
1 196 ILE n 
1 197 ILE n 
1 198 ALA n 
1 199 VAL n 
1 200 TRP n 
1 201 THR n 
1 202 ILE n 
1 203 SER n 
1 204 VAL n 
1 205 GLY n 
1 206 ILE n 
1 207 SER n 
1 208 MET n 
1 209 PRO n 
1 210 ILE n 
1 211 PRO n 
1 212 VAL n 
1 213 PHE n 
1 214 GLY n 
1 215 LEU n 
1 216 GLN n 
1 217 ASP n 
1 218 ASP n 
1 219 SER n 
1 220 LYS n 
1 221 VAL n 
1 222 PHE n 
1 223 LYS n 
1 224 GLU n 
1 225 GLY n 
1 226 SER n 
1 227 CYS n 
1 228 LEU n 
1 229 LEU n 
1 230 ALA n 
1 231 ASP n 
1 232 ASP n 
1 233 ASN n 
1 234 PHE n 
1 235 VAL n 
1 236 LEU n 
1 237 ILE n 
1 238 GLY n 
1 239 SER n 
1 240 PHE n 
1 241 VAL n 
1 242 SER n 
1 243 PHE n 
1 244 PHE n 
1 245 ILE n 
1 246 PRO n 
1 247 LEU n 
1 248 THR n 
1 249 ILE n 
1 250 MET n 
1 251 VAL n 
1 252 ILE n 
1 253 THR n 
1 254 TYR n 
1 255 PHE n 
1 256 LEU n 
1 257 THR n 
1 258 ILE n 
1 259 LYS n 
1 260 SER n 
1 261 LEU n 
1 262 GLN n 
1 263 LYS n 
1 264 GLU n 
1 265 ALA n 
1 266 THR n 
1 267 LEU n 
1 268 CYS n 
1 269 VAL n 
1 270 SER n 
1 271 ASP n 
1 272 LEU n 
1 273 GLY n 
1 274 THR n 
1 275 ARG n 
1 276 ALA n 
1 277 LYS n 
1 278 LEU n 
1 279 ALA n 
1 280 SER n 
1 281 PHE n 
1 282 SER n 
1 283 PHE n 
1 284 LEU n 
1 285 PRO n 
1 286 GLN n 
1 287 SER n 
1 288 SER n 
1 289 LEU n 
1 290 SER n 
1 291 SER n 
1 292 GLU n 
1 293 LYS n 
1 294 LEU n 
1 295 PHE n 
1 296 GLN n 
1 297 ARG n 
1 298 SER n 
1 299 ILE n 
1 300 HIS n 
1 301 ARG n 
1 302 GLU n 
1 303 PRO n 
1 304 GLY n 
1 305 SER n 
1 306 TYR n 
1 307 THR n 
1 308 GLY n 
1 309 ARG n 
1 310 ARG n 
1 311 THR n 
1 312 MET n 
1 313 GLN n 
1 314 SER n 
1 315 ILE n 
1 316 SER n 
1 317 ASN n 
1 318 GLU n 
1 319 GLN n 
1 320 LYS n 
1 321 ALA n 
1 322 CYS n 
1 323 LYS n 
1 324 VAL n 
1 325 LEU n 
1 326 GLY n 
1 327 ILE n 
1 328 VAL n 
1 329 PHE n 
1 330 PHE n 
1 331 LEU n 
1 332 PHE n 
1 333 VAL n 
1 334 VAL n 
1 335 MET n 
1 336 TRP n 
1 337 CYS n 
1 338 PRO n 
1 339 PHE n 
1 340 PHE n 
1 341 ILE n 
1 342 THR n 
1 343 ASN n 
1 344 ILE n 
1 345 MET n 
1 346 ALA n 
1 347 VAL n 
1 348 ILE n 
1 349 CYS n 
1 350 LYS n 
1 351 GLU n 
1 352 SER n 
1 353 CYS n 
1 354 ASN n 
1 355 GLU n 
1 356 ASP n 
1 357 VAL n 
1 358 ILE n 
1 359 GLY n 
1 360 ALA n 
1 361 LEU n 
1 362 LEU n 
1 363 ASN n 
1 364 VAL n 
1 365 PHE n 
1 366 VAL n 
1 367 TRP n 
1 368 ILE n 
1 369 GLY n 
1 370 TYR n 
1 371 LEU n 
1 372 SER n 
1 373 SER n 
1 374 ALA n 
1 375 VAL n 
1 376 ASN n 
1 377 PRO n 
1 378 LEU n 
1 379 VAL n 
1 380 TYR n 
1 381 THR n 
1 382 LEU n 
1 383 PHE n 
1 384 ASN n 
1 385 LYS n 
1 386 THR n 
1 387 TYR n 
1 388 ARG n 
1 389 SER n 
1 390 ALA n 
1 391 PHE n 
1 392 SER n 
1 393 ARG n 
1 394 TYR n 
1 395 ILE n 
1 396 GLN n 
1 397 CYS n 
1 398 GLN n 
1 399 TYR n 
1 400 LYS n 
1 401 GLU n 
1 402 ASN n 
1 403 LYS n 
1 404 LYS n 
1 405 PRO n 
1 406 LEU n 
1 407 GLN n 
1 408 LEU n 
1 409 ILE n 
1 410 LEU n 
1 411 VAL n 
1 412 ASN n 
1 413 THR n 
1 414 ILE n 
1 415 PRO n 
1 416 ALA n 
1 417 LEU n 
1 418 ALA n 
1 419 TYR n 
1 420 LYS n 
1 421 SER n 
1 422 SER n 
1 423 GLN n 
1 424 LEU n 
1 425 GLN n 
1 426 MET n 
1 427 GLY n 
1 428 GLN n 
1 429 LYS n 
1 430 LYS n 
1 431 ASN n 
1 432 SER n 
1 433 LYS n 
1 434 GLN n 
1 435 ASP n 
1 436 ALA n 
1 437 LYS n 
1 438 THR n 
1 439 THR n 
1 440 ASP n 
1 441 ASN n 
1 442 ASP n 
1 443 CYS n 
1 444 SER n 
1 445 MET n 
1 446 VAL n 
1 447 ALA n 
1 448 LEU n 
1 449 GLY n 
1 450 LYS n 
1 451 GLN n 
1 452 HIS n 
1 453 SER n 
1 454 GLU n 
1 455 GLU n 
1 456 ALA n 
1 457 SER n 
1 458 LYS n 
1 459 ASP n 
1 460 ASN n 
1 461 SER n 
1 462 ASP n 
1 463 GLY n 
1 464 VAL n 
1 465 ASN n 
1 466 GLU n 
1 467 LYS n 
1 468 VAL n 
1 469 SER n 
1 470 CYS n 
1 471 VAL n 
2 1   MET n 
2 2   GLY n 
2 3   SER n 
2 4   THR n 
2 5   VAL n 
2 6   SER n 
2 7   ALA n 
2 8   GLU n 
2 9   ASP n 
2 10  LYS n 
2 11  ALA n 
2 12  ALA n 
2 13  ALA n 
2 14  GLU n 
2 15  ARG n 
2 16  SER n 
2 17  LYS n 
2 18  MET n 
2 19  ILE n 
2 20  ASP n 
2 21  LYS n 
2 22  ASN n 
2 23  LEU n 
2 24  ARG n 
2 25  GLU n 
2 26  ASP n 
2 27  GLY n 
2 28  GLU n 
2 29  LYS n 
2 30  ALA n 
2 31  ARG n 
2 32  ARG n 
2 33  THR n 
2 34  LEU n 
2 35  ARG n 
2 36  LEU n 
2 37  LEU n 
2 38  LEU n 
2 39  LEU n 
2 40  GLY n 
2 41  ALA n 
2 42  ASP n 
2 43  ASN n 
2 44  SER n 
2 45  GLY n 
2 46  LYS n 
2 47  SER n 
2 48  THR n 
2 49  ILE n 
2 50  VAL n 
2 51  LYS n 
2 52  GLN n 
2 53  MET n 
2 54  ARG n 
2 55  ILE n 
2 56  LEU n 
2 57  HIS n 
2 58  GLY n 
2 59  GLY n 
2 60  SER n 
2 61  GLY n 
2 62  GLY n 
2 63  SER n 
2 64  GLY n 
2 65  GLY n 
2 66  THR n 
2 67  SER n 
2 68  GLY n 
2 69  ILE n 
2 70  PHE n 
2 71  GLU n 
2 72  THR n 
2 73  LYS n 
2 74  PHE n 
2 75  GLN n 
2 76  VAL n 
2 77  ASP n 
2 78  LYS n 
2 79  VAL n 
2 80  ASN n 
2 81  PHE n 
2 82  HIS n 
2 83  MET n 
2 84  PHE n 
2 85  ASP n 
2 86  VAL n 
2 87  GLY n 
2 88  GLY n 
2 89  GLN n 
2 90  ARG n 
2 91  ASP n 
2 92  GLU n 
2 93  ARG n 
2 94  ARG n 
2 95  LYS n 
2 96  TRP n 
2 97  ILE n 
2 98  GLN n 
2 99  CYS n 
2 100 PHE n 
2 101 ASN n 
2 102 ASP n 
2 103 VAL n 
2 104 THR n 
2 105 ALA n 
2 106 ILE n 
2 107 ILE n 
2 108 PHE n 
2 109 VAL n 
2 110 VAL n 
2 111 ASP n 
2 112 SER n 
2 113 SER n 
2 114 ASP n 
2 115 TYR n 
2 116 ASN n 
2 117 ARG n 
2 118 LEU n 
2 119 GLN n 
2 120 GLU n 
2 121 ALA n 
2 122 LEU n 
2 123 ASN n 
2 124 ASP n 
2 125 PHE n 
2 126 LYS n 
2 127 SER n 
2 128 ILE n 
2 129 TRP n 
2 130 ASN n 
2 131 ASN n 
2 132 ARG n 
2 133 TRP n 
2 134 LEU n 
2 135 ARG n 
2 136 THR n 
2 137 ILE n 
2 138 SER n 
2 139 VAL n 
2 140 ILE n 
2 141 LEU n 
2 142 PHE n 
2 143 LEU n 
2 144 ASN n 
2 145 LYS n 
2 146 GLN n 
2 147 ASP n 
2 148 LEU n 
2 149 LEU n 
2 150 ALA n 
2 151 GLU n 
2 152 LYS n 
2 153 VAL n 
2 154 LEU n 
2 155 ALA n 
2 156 GLY n 
2 157 LYS n 
2 158 SER n 
2 159 LYS n 
2 160 ILE n 
2 161 GLU n 
2 162 ASP n 
2 163 TYR n 
2 164 PHE n 
2 165 PRO n 
2 166 GLU n 
2 167 PHE n 
2 168 ALA n 
2 169 ARG n 
2 170 TYR n 
2 171 THR n 
2 172 THR n 
2 173 PRO n 
2 174 GLU n 
2 175 ASP n 
2 176 ALA n 
2 177 THR n 
2 178 PRO n 
2 179 GLU n 
2 180 PRO n 
2 181 GLY n 
2 182 GLU n 
2 183 ASP n 
2 184 PRO n 
2 185 ARG n 
2 186 VAL n 
2 187 THR n 
2 188 ARG n 
2 189 ALA n 
2 190 LYS n 
2 191 TYR n 
2 192 PHE n 
2 193 ILE n 
2 194 ARG n 
2 195 LYS n 
2 196 GLU n 
2 197 PHE n 
2 198 VAL n 
2 199 ASP n 
2 200 ILE n 
2 201 SER n 
2 202 THR n 
2 203 ALA n 
2 204 SER n 
2 205 GLY n 
2 206 ASP n 
2 207 GLY n 
2 208 ARG n 
2 209 HIS n 
2 210 ILE n 
2 211 CYS n 
2 212 TYR n 
2 213 PRO n 
2 214 HIS n 
2 215 PHE n 
2 216 THR n 
2 217 CYS n 
2 218 ALA n 
2 219 VAL n 
2 220 ASP n 
2 221 THR n 
2 222 GLU n 
2 223 ASN n 
2 224 ALA n 
2 225 ARG n 
2 226 ARG n 
2 227 ILE n 
2 228 PHE n 
2 229 ASN n 
2 230 ASP n 
2 231 CYS n 
2 232 LYS n 
2 233 ASP n 
2 234 ILE n 
2 235 ILE n 
2 236 LEU n 
2 237 GLN n 
2 238 MET n 
2 239 ASN n 
2 240 LEU n 
2 241 ARG n 
2 242 GLU n 
2 243 TYR n 
2 244 ASN n 
2 245 LEU n 
2 246 VAL n 
3 1   MET n 
3 2   HIS n 
3 3   HIS n 
3 4   HIS n 
3 5   HIS n 
3 6   HIS n 
3 7   HIS n 
3 8   LEU n 
3 9   GLU n 
3 10  VAL n 
3 11  LEU n 
3 12  PHE n 
3 13  GLN n 
3 14  GLY n 
3 15  PRO n 
3 16  GLY n 
3 17  SER n 
3 18  SER n 
3 19  GLY n 
3 20  SER n 
3 21  GLU n 
3 22  LEU n 
3 23  ASP n 
3 24  GLN n 
3 25  LEU n 
3 26  ARG n 
3 27  GLN n 
3 28  GLU n 
3 29  ALA n 
3 30  GLU n 
3 31  GLN n 
3 32  LEU n 
3 33  LYS n 
3 34  ASN n 
3 35  GLN n 
3 36  ILE n 
3 37  ARG n 
3 38  ASP n 
3 39  ALA n 
3 40  ARG n 
3 41  LYS n 
3 42  ALA n 
3 43  CYS n 
3 44  ALA n 
3 45  ASP n 
3 46  ALA n 
3 47  THR n 
3 48  LEU n 
3 49  SER n 
3 50  GLN n 
3 51  ILE n 
3 52  THR n 
3 53  ASN n 
3 54  ASN n 
3 55  ILE n 
3 56  ASP n 
3 57  PRO n 
3 58  VAL n 
3 59  GLY n 
3 60  ARG n 
3 61  ILE n 
3 62  GLN n 
3 63  MET n 
3 64  ARG n 
3 65  THR n 
3 66  ARG n 
3 67  ARG n 
3 68  THR n 
3 69  LEU n 
3 70  ARG n 
3 71  GLY n 
3 72  HIS n 
3 73  LEU n 
3 74  ALA n 
3 75  LYS n 
3 76  ILE n 
3 77  TYR n 
3 78  ALA n 
3 79  MET n 
3 80  HIS n 
3 81  TRP n 
3 82  GLY n 
3 83  THR n 
3 84  ASP n 
3 85  SER n 
3 86  ARG n 
3 87  LEU n 
3 88  LEU n 
3 89  VAL n 
3 90  SER n 
3 91  ALA n 
3 92  SER n 
3 93  GLN n 
3 94  ASP n 
3 95  GLY n 
3 96  LYS n 
3 97  LEU n 
3 98  ILE n 
3 99  ILE n 
3 100 TRP n 
3 101 ASP n 
3 102 SER n 
3 103 TYR n 
3 104 THR n 
3 105 THR n 
3 106 ASN n 
3 107 LYS n 
3 108 VAL n 
3 109 HIS n 
3 110 ALA n 
3 111 ILE n 
3 112 PRO n 
3 113 LEU n 
3 114 ARG n 
3 115 SER n 
3 116 SER n 
3 117 TRP n 
3 118 VAL n 
3 119 MET n 
3 120 THR n 
3 121 CYS n 
3 122 ALA n 
3 123 TYR n 
3 124 ALA n 
3 125 PRO n 
3 126 SER n 
3 127 GLY n 
3 128 ASN n 
3 129 TYR n 
3 130 VAL n 
3 131 ALA n 
3 132 CYS n 
3 133 GLY n 
3 134 GLY n 
3 135 LEU n 
3 136 ASP n 
3 137 ASN n 
3 138 ILE n 
3 139 CYS n 
3 140 SER n 
3 141 ILE n 
3 142 TYR n 
3 143 ASN n 
3 144 LEU n 
3 145 LYS n 
3 146 THR n 
3 147 ARG n 
3 148 GLU n 
3 149 GLY n 
3 150 ASN n 
3 151 VAL n 
3 152 ARG n 
3 153 VAL n 
3 154 SER n 
3 155 ARG n 
3 156 GLU n 
3 157 LEU n 
3 158 ALA n 
3 159 GLY n 
3 160 HIS n 
3 161 THR n 
3 162 GLY n 
3 163 TYR n 
3 164 LEU n 
3 165 SER n 
3 166 CYS n 
3 167 CYS n 
3 168 ARG n 
3 169 PHE n 
3 170 LEU n 
3 171 ASP n 
3 172 ASP n 
3 173 ASN n 
3 174 GLN n 
3 175 ILE n 
3 176 VAL n 
3 177 THR n 
3 178 SER n 
3 179 SER n 
3 180 GLY n 
3 181 ASP n 
3 182 THR n 
3 183 THR n 
3 184 CYS n 
3 185 ALA n 
3 186 LEU n 
3 187 TRP n 
3 188 ASP n 
3 189 ILE n 
3 190 GLU n 
3 191 THR n 
3 192 GLY n 
3 193 GLN n 
3 194 GLN n 
3 195 THR n 
3 196 THR n 
3 197 THR n 
3 198 PHE n 
3 199 THR n 
3 200 GLY n 
3 201 HIS n 
3 202 THR n 
3 203 GLY n 
3 204 ASP n 
3 205 VAL n 
3 206 MET n 
3 207 SER n 
3 208 LEU n 
3 209 SER n 
3 210 LEU n 
3 211 ALA n 
3 212 PRO n 
3 213 ASP n 
3 214 THR n 
3 215 ARG n 
3 216 LEU n 
3 217 PHE n 
3 218 VAL n 
3 219 SER n 
3 220 GLY n 
3 221 ALA n 
3 222 CYS n 
3 223 ASP n 
3 224 ALA n 
3 225 SER n 
3 226 ALA n 
3 227 LYS n 
3 228 LEU n 
3 229 TRP n 
3 230 ASP n 
3 231 VAL n 
3 232 ARG n 
3 233 GLU n 
3 234 GLY n 
3 235 MET n 
3 236 CYS n 
3 237 ARG n 
3 238 GLN n 
3 239 THR n 
3 240 PHE n 
3 241 THR n 
3 242 GLY n 
3 243 HIS n 
3 244 GLU n 
3 245 SER n 
3 246 ASP n 
3 247 ILE n 
3 248 ASN n 
3 249 ALA n 
3 250 ILE n 
3 251 CYS n 
3 252 PHE n 
3 253 PHE n 
3 254 PRO n 
3 255 ASN n 
3 256 GLY n 
3 257 ASN n 
3 258 ALA n 
3 259 PHE n 
3 260 ALA n 
3 261 THR n 
3 262 GLY n 
3 263 SER n 
3 264 ASP n 
3 265 ASP n 
3 266 ALA n 
3 267 THR n 
3 268 CYS n 
3 269 ARG n 
3 270 LEU n 
3 271 PHE n 
3 272 ASP n 
3 273 LEU n 
3 274 ARG n 
3 275 ALA n 
3 276 ASP n 
3 277 GLN n 
3 278 GLU n 
3 279 LEU n 
3 280 MET n 
3 281 THR n 
3 282 TYR n 
3 283 SER n 
3 284 HIS n 
3 285 ASP n 
3 286 ASN n 
3 287 ILE n 
3 288 ILE n 
3 289 CYS n 
3 290 GLY n 
3 291 ILE n 
3 292 THR n 
3 293 SER n 
3 294 VAL n 
3 295 SER n 
3 296 PHE n 
3 297 SER n 
3 298 LYS n 
3 299 SER n 
3 300 GLY n 
3 301 ARG n 
3 302 LEU n 
3 303 LEU n 
3 304 LEU n 
3 305 ALA n 
3 306 GLY n 
3 307 TYR n 
3 308 ASP n 
3 309 ASP n 
3 310 PHE n 
3 311 ASN n 
3 312 CYS n 
3 313 ASN n 
3 314 VAL n 
3 315 TRP n 
3 316 ASP n 
3 317 ALA n 
3 318 LEU n 
3 319 LYS n 
3 320 ALA n 
3 321 ASP n 
3 322 ARG n 
3 323 ALA n 
3 324 GLY n 
3 325 VAL n 
3 326 LEU n 
3 327 ALA n 
3 328 GLY n 
3 329 HIS n 
3 330 ASP n 
3 331 ASN n 
3 332 ARG n 
3 333 VAL n 
3 334 SER n 
3 335 CYS n 
3 336 LEU n 
3 337 GLY n 
3 338 VAL n 
3 339 THR n 
3 340 ASP n 
3 341 ASP n 
3 342 GLY n 
3 343 MET n 
3 344 ALA n 
3 345 VAL n 
3 346 ALA n 
3 347 THR n 
3 348 GLY n 
3 349 SER n 
3 350 TRP n 
3 351 ASP n 
3 352 SER n 
3 353 PHE n 
3 354 LEU n 
3 355 LYS n 
3 356 ILE n 
3 357 TRP n 
3 358 ASN n 
4 1   MET n 
4 2   ALA n 
4 3   SER n 
4 4   ASN n 
4 5   ASN n 
4 6   THR n 
4 7   ALA n 
4 8   SER n 
4 9   ILE n 
4 10  ALA n 
4 11  GLN n 
4 12  ALA n 
4 13  ARG n 
4 14  LYS n 
4 15  LEU n 
4 16  VAL n 
4 17  GLU n 
4 18  GLN n 
4 19  LEU n 
4 20  LYS n 
4 21  MET n 
4 22  GLU n 
4 23  ALA n 
4 24  ASN n 
4 25  ILE n 
4 26  ASP n 
4 27  ARG n 
4 28  ILE n 
4 29  LYS n 
4 30  VAL n 
4 31  SER n 
4 32  LYS n 
4 33  ALA n 
4 34  ALA n 
4 35  ALA n 
4 36  ASP n 
4 37  LEU n 
4 38  MET n 
4 39  ALA n 
4 40  TYR n 
4 41  CYS n 
4 42  GLU n 
4 43  ALA n 
4 44  HIS n 
4 45  ALA n 
4 46  LYS n 
4 47  GLU n 
4 48  ASP n 
4 49  PRO n 
4 50  LEU n 
4 51  LEU n 
4 52  THR n 
4 53  PRO n 
4 54  VAL n 
4 55  PRO n 
4 56  ALA n 
4 57  SER n 
4 58  GLU n 
4 59  ASN n 
4 60  PRO n 
4 61  PHE n 
4 62  ARG n 
4 63  GLU n 
4 64  LYS n 
4 65  LYS n 
4 66  PHE n 
4 67  PHE n 
4 68  CYS n 
4 69  ALA n 
4 70  ILE n 
4 71  LEU n 
5 1   ASP n 
5 2   VAL n 
5 3   GLN n 
5 4   LEU n 
5 5   VAL n 
5 6   GLU n 
5 7   SER n 
5 8   GLY n 
5 9   GLY n 
5 10  GLY n 
5 11  LEU n 
5 12  VAL n 
5 13  GLN n 
5 14  PRO n 
5 15  GLY n 
5 16  GLY n 
5 17  SER n 
5 18  ARG n 
5 19  LYS n 
5 20  LEU n 
5 21  SER n 
5 22  CYS n 
5 23  SER n 
5 24  ALA n 
5 25  SER n 
5 26  GLY n 
5 27  PHE n 
5 28  ALA n 
5 29  PHE n 
5 30  SER n 
5 31  SER n 
5 32  PHE n 
5 33  GLY n 
5 34  MET n 
5 35  HIS n 
5 36  TRP n 
5 37  VAL n 
5 38  ARG n 
5 39  GLN n 
5 40  ALA n 
5 41  PRO n 
5 42  GLU n 
5 43  LYS n 
5 44  GLY n 
5 45  LEU n 
5 46  GLU n 
5 47  TRP n 
5 48  VAL n 
5 49  ALA n 
5 50  TYR n 
5 51  ILE n 
5 52  SER n 
5 53  SER n 
5 54  GLY n 
5 55  SER n 
5 56  GLY n 
5 57  THR n 
5 58  ILE n 
5 59  TYR n 
5 60  TYR n 
5 61  ALA n 
5 62  ASP n 
5 63  THR n 
5 64  VAL n 
5 65  LYS n 
5 66  GLY n 
5 67  ARG n 
5 68  PHE n 
5 69  THR n 
5 70  ILE n 
5 71  SER n 
5 72  ARG n 
5 73  ASP n 
5 74  ASP n 
5 75  PRO n 
5 76  LYS n 
5 77  ASN n 
5 78  THR n 
5 79  LEU n 
5 80  PHE n 
5 81  LEU n 
5 82  GLN n 
5 83  MET n 
5 84  THR n 
5 85  SER n 
5 86  LEU n 
5 87  ARG n 
5 88  SER n 
5 89  GLU n 
5 90  ASP n 
5 91  THR n 
5 92  ALA n 
5 93  MET n 
5 94  TYR n 
5 95  TYR n 
5 96  CYS n 
5 97  VAL n 
5 98  ARG n 
5 99  SER n 
5 100 ILE n 
5 101 TYR n 
5 102 TYR n 
5 103 TYR n 
5 104 GLY n 
5 105 SER n 
5 106 SER n 
5 107 PRO n 
5 108 PHE n 
5 109 ASP n 
5 110 PHE n 
5 111 TRP n 
5 112 GLY n 
5 113 GLN n 
5 114 GLY n 
5 115 THR n 
5 116 THR n 
5 117 LEU n 
5 118 THR n 
5 119 VAL n 
5 120 SER n 
5 121 SER n 
5 122 GLY n 
5 123 GLY n 
5 124 GLY n 
5 125 GLY n 
5 126 SER n 
5 127 GLY n 
5 128 GLY n 
5 129 GLY n 
5 130 GLY n 
5 131 SER n 
5 132 GLY n 
5 133 GLY n 
5 134 GLY n 
5 135 GLY n 
5 136 SER n 
5 137 ASP n 
5 138 ILE n 
5 139 VAL n 
5 140 MET n 
5 141 THR n 
5 142 GLN n 
5 143 ALA n 
5 144 THR n 
5 145 SER n 
5 146 SER n 
5 147 VAL n 
5 148 PRO n 
5 149 VAL n 
5 150 THR n 
5 151 PRO n 
5 152 GLY n 
5 153 GLU n 
5 154 SER n 
5 155 VAL n 
5 156 SER n 
5 157 ILE n 
5 158 SER n 
5 159 CYS n 
5 160 ARG n 
5 161 SER n 
5 162 SER n 
5 163 LYS n 
5 164 SER n 
5 165 LEU n 
5 166 LEU n 
5 167 HIS n 
5 168 SER n 
5 169 ASN n 
5 170 GLY n 
5 171 ASN n 
5 172 THR n 
5 173 TYR n 
5 174 LEU n 
5 175 TYR n 
5 176 TRP n 
5 177 PHE n 
5 178 LEU n 
5 179 GLN n 
5 180 ARG n 
5 181 PRO n 
5 182 GLY n 
5 183 GLN n 
5 184 SER n 
5 185 PRO n 
5 186 GLN n 
5 187 LEU n 
5 188 LEU n 
5 189 ILE n 
5 190 TYR n 
5 191 ARG n 
5 192 MET n 
5 193 SER n 
5 194 ASN n 
5 195 LEU n 
5 196 ALA n 
5 197 SER n 
5 198 GLY n 
5 199 VAL n 
5 200 PRO n 
5 201 ASP n 
5 202 ARG n 
5 203 PHE n 
5 204 SER n 
5 205 GLY n 
5 206 SER n 
5 207 GLY n 
5 208 SER n 
5 209 GLY n 
5 210 THR n 
5 211 ALA n 
5 212 PHE n 
5 213 THR n 
5 214 LEU n 
5 215 THR n 
5 216 ILE n 
5 217 SER n 
5 218 ARG n 
5 219 LEU n 
5 220 GLU n 
5 221 ALA n 
5 222 GLU n 
5 223 ASP n 
5 224 VAL n 
5 225 GLY n 
5 226 VAL n 
5 227 TYR n 
5 228 TYR n 
5 229 CYS n 
5 230 MET n 
5 231 GLN n 
5 232 HIS n 
5 233 LEU n 
5 234 GLU n 
5 235 TYR n 
5 236 PRO n 
5 237 LEU n 
5 238 THR n 
5 239 PHE n 
5 240 GLY n 
5 241 ALA n 
5 242 GLY n 
5 243 THR n 
5 244 LYS n 
5 245 LEU n 
5 246 GLU n 
5 247 LEU n 
5 248 LYS n 
5 249 ALA n 
5 250 ALA n 
5 251 ALA n 
5 252 LEU n 
5 253 GLU n 
5 254 VAL n 
5 255 LEU n 
5 256 PHE n 
5 257 GLN n 
5 258 GLY n 
5 259 PRO n 
5 260 HIS n 
5 261 HIS n 
5 262 HIS n 
5 263 HIS n 
5 264 HIS n 
5 265 HIS n 
5 266 HIS n 
5 267 HIS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 471 human ? 'HTR2A, HTR2' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 'fall armyworm' 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? baculovirus ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 246 human ? ?             ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 'fall armyworm' 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? baculovirus ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 358 human ? GNB1          ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 'fall armyworm' 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? baculovirus ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1 71  human ? GNG2          ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 'fall armyworm' 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? baculovirus ? ? ? ? ? ? 
5 1 sample 'Biological sequence' 1 267 human ? ?             ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 'fall armyworm' 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? baculovirus ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
7LD non-polymer         . '(8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide' 'Lysergic acid diethylamide' 
'C20 H25 N3 O'   323.432 
ALA 'L-peptide linking' y ALANINE                                                              ?                            
'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                                                             ?                            
'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                                                           ?                            
'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                                                      ?                            
'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                                                             ?                            
'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE                                                            ?                            
'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                                                      ?                            
'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                                                              ?                            
'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                                                            ?                            
'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE                                                           ?                            
'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                                                              ?                            
'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                                                               ?                            
'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                                                           ?                            
'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE                                                        ?                            
'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                                                              ?                            
'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                                                               ?                            
'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                                                            ?                            
'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                                           ?                            
'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                                                             ?                            
'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                                                               ?                            
'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   ASP 2   2   ?   ?   ?   A . n 
A 1 3   ILE 3   3   ?   ?   ?   A . n 
A 1 4   LEU 4   4   ?   ?   ?   A . n 
A 1 5   CYS 5   5   ?   ?   ?   A . n 
A 1 6   GLU 6   6   ?   ?   ?   A . n 
A 1 7   GLU 7   7   ?   ?   ?   A . n 
A 1 8   ASN 8   8   ?   ?   ?   A . n 
A 1 9   THR 9   9   ?   ?   ?   A . n 
A 1 10  SER 10  10  ?   ?   ?   A . n 
A 1 11  LEU 11  11  ?   ?   ?   A . n 
A 1 12  SER 12  12  ?   ?   ?   A . n 
A 1 13  SER 13  13  ?   ?   ?   A . n 
A 1 14  THR 14  14  ?   ?   ?   A . n 
A 1 15  THR 15  15  ?   ?   ?   A . n 
A 1 16  ASN 16  16  ?   ?   ?   A . n 
A 1 17  SER 17  17  ?   ?   ?   A . n 
A 1 18  LEU 18  18  ?   ?   ?   A . n 
A 1 19  MET 19  19  ?   ?   ?   A . n 
A 1 20  GLN 20  20  ?   ?   ?   A . n 
A 1 21  LEU 21  21  ?   ?   ?   A . n 
A 1 22  ASN 22  22  ?   ?   ?   A . n 
A 1 23  ASP 23  23  ?   ?   ?   A . n 
A 1 24  ASP 24  24  ?   ?   ?   A . n 
A 1 25  THR 25  25  ?   ?   ?   A . n 
A 1 26  ARG 26  26  ?   ?   ?   A . n 
A 1 27  LEU 27  27  ?   ?   ?   A . n 
A 1 28  TYR 28  28  ?   ?   ?   A . n 
A 1 29  SER 29  29  ?   ?   ?   A . n 
A 1 30  ASN 30  30  ?   ?   ?   A . n 
A 1 31  ASP 31  31  ?   ?   ?   A . n 
A 1 32  PHE 32  32  ?   ?   ?   A . n 
A 1 33  ASN 33  33  ?   ?   ?   A . n 
A 1 34  SER 34  34  ?   ?   ?   A . n 
A 1 35  GLY 35  35  ?   ?   ?   A . n 
A 1 36  GLU 36  36  ?   ?   ?   A . n 
A 1 37  ALA 37  37  ?   ?   ?   A . n 
A 1 38  ASN 38  38  ?   ?   ?   A . n 
A 1 39  THR 39  39  ?   ?   ?   A . n 
A 1 40  SER 40  40  ?   ?   ?   A . n 
A 1 41  ASP 41  41  ?   ?   ?   A . n 
A 1 42  ALA 42  42  ?   ?   ?   A . n 
A 1 43  PHE 43  43  ?   ?   ?   A . n 
A 1 44  ASN 44  44  ?   ?   ?   A . n 
A 1 45  TRP 45  45  ?   ?   ?   A . n 
A 1 46  THR 46  46  ?   ?   ?   A . n 
A 1 47  VAL 47  47  ?   ?   ?   A . n 
A 1 48  ASP 48  48  ?   ?   ?   A . n 
A 1 49  SER 49  49  ?   ?   ?   A . n 
A 1 50  GLU 50  50  ?   ?   ?   A . n 
A 1 51  ASN 51  51  ?   ?   ?   A . n 
A 1 52  ARG 52  52  ?   ?   ?   A . n 
A 1 53  THR 53  53  ?   ?   ?   A . n 
A 1 54  ASN 54  54  ?   ?   ?   A . n 
A 1 55  LEU 55  55  ?   ?   ?   A . n 
A 1 56  SER 56  56  ?   ?   ?   A . n 
A 1 57  CYS 57  57  ?   ?   ?   A . n 
A 1 58  GLU 58  58  ?   ?   ?   A . n 
A 1 59  GLY 59  59  ?   ?   ?   A . n 
A 1 60  CYS 60  60  ?   ?   ?   A . n 
A 1 61  LEU 61  61  ?   ?   ?   A . n 
A 1 62  SER 62  62  ?   ?   ?   A . n 
A 1 63  PRO 63  63  ?   ?   ?   A . n 
A 1 64  SER 64  64  ?   ?   ?   A . n 
A 1 65  CYS 65  65  ?   ?   ?   A . n 
A 1 66  LEU 66  66  ?   ?   ?   A . n 
A 1 67  SER 67  67  ?   ?   ?   A . n 
A 1 68  LEU 68  68  ?   ?   ?   A . n 
A 1 69  LEU 69  69  ?   ?   ?   A . n 
A 1 70  HIS 70  70  ?   ?   ?   A . n 
A 1 71  LEU 71  71  ?   ?   ?   A . n 
A 1 72  GLN 72  72  ?   ?   ?   A . n 
A 1 73  GLU 73  73  ?   ?   ?   A . n 
A 1 74  LYS 74  74  ?   ?   ?   A . n 
A 1 75  ASN 75  75  ?   ?   ?   A . n 
A 1 76  TRP 76  76  ?   ?   ?   A . n 
A 1 77  SER 77  77  ?   ?   ?   A . n 
A 1 78  ALA 78  78  ?   ?   ?   A . n 
A 1 79  LEU 79  79  ?   ?   ?   A . n 
A 1 80  LEU 80  80  ?   ?   ?   A . n 
A 1 81  THR 81  81  ?   ?   ?   A . n 
A 1 82  ALA 82  82  ?   ?   ?   A . n 
A 1 83  VAL 83  83  ?   ?   ?   A . n 
A 1 84  VAL 84  84  84  VAL VAL A . n 
A 1 85  ILE 85  85  85  ILE ILE A . n 
A 1 86  ILE 86  86  86  ILE ILE A . n 
A 1 87  LEU 87  87  87  LEU LEU A . n 
A 1 88  THR 88  88  88  THR THR A . n 
A 1 89  ILE 89  89  89  ILE ILE A . n 
A 1 90  ALA 90  90  90  ALA ALA A . n 
A 1 91  GLY 91  91  91  GLY GLY A . n 
A 1 92  ASN 92  92  92  ASN ASN A . n 
A 1 93  ILE 93  93  93  ILE ILE A . n 
A 1 94  LEU 94  94  94  LEU LEU A . n 
A 1 95  VAL 95  95  95  VAL VAL A . n 
A 1 96  ILE 96  96  96  ILE ILE A . n 
A 1 97  MET 97  97  97  MET MET A . n 
A 1 98  ALA 98  98  98  ALA ALA A . n 
A 1 99  VAL 99  99  99  VAL VAL A . n 
A 1 100 SER 100 100 ?   ?   ?   A . n 
A 1 101 LEU 101 101 ?   ?   ?   A . n 
A 1 102 GLU 102 102 ?   ?   ?   A . n 
A 1 103 LYS 103 103 ?   ?   ?   A . n 
A 1 104 LYS 104 104 ?   ?   ?   A . n 
A 1 105 LEU 105 105 105 LEU LEU A . n 
A 1 106 GLN 106 106 106 GLN GLN A . n 
A 1 107 ASN 107 107 107 ASN ASN A . n 
A 1 108 ALA 108 108 108 ALA ALA A . n 
A 1 109 THR 109 109 109 THR THR A . n 
A 1 110 ASN 110 110 110 ASN ASN A . n 
A 1 111 TYR 111 111 111 TYR TYR A . n 
A 1 112 PHE 112 112 112 PHE PHE A . n 
A 1 113 LEU 113 113 113 LEU LEU A . n 
A 1 114 MET 114 114 114 MET MET A . n 
A 1 115 SER 115 115 115 SER SER A . n 
A 1 116 LEU 116 116 116 LEU LEU A . n 
A 1 117 ALA 117 117 117 ALA ALA A . n 
A 1 118 ILE 118 118 118 ILE ILE A . n 
A 1 119 ALA 119 119 119 ALA ALA A . n 
A 1 120 ASP 120 120 120 ASP ASP A . n 
A 1 121 MET 121 121 121 MET MET A . n 
A 1 122 LEU 122 122 122 LEU LEU A . n 
A 1 123 LEU 123 123 123 LEU LEU A . n 
A 1 124 GLY 124 124 124 GLY GLY A . n 
A 1 125 PHE 125 125 125 PHE PHE A . n 
A 1 126 LEU 126 126 126 LEU LEU A . n 
A 1 127 VAL 127 127 127 VAL VAL A . n 
A 1 128 MET 128 128 128 MET MET A . n 
A 1 129 PRO 129 129 129 PRO PRO A . n 
A 1 130 VAL 130 130 130 VAL VAL A . n 
A 1 131 SER 131 131 131 SER SER A . n 
A 1 132 MET 132 132 132 MET MET A . n 
A 1 133 LEU 133 133 133 LEU LEU A . n 
A 1 134 THR 134 134 134 THR THR A . n 
A 1 135 ILE 135 135 135 ILE ILE A . n 
A 1 136 LEU 136 136 136 LEU LEU A . n 
A 1 137 TYR 137 137 137 TYR TYR A . n 
A 1 138 GLY 138 138 138 GLY GLY A . n 
A 1 139 TYR 139 139 139 TYR TYR A . n 
A 1 140 ARG 140 140 140 ARG ARG A . n 
A 1 141 TRP 141 141 141 TRP TRP A . n 
A 1 142 PRO 142 142 142 PRO PRO A . n 
A 1 143 LEU 143 143 ?   ?   ?   A . n 
A 1 144 PRO 144 144 ?   ?   ?   A . n 
A 1 145 SER 145 145 145 SER SER A . n 
A 1 146 LYS 146 146 146 LYS LYS A . n 
A 1 147 LEU 147 147 147 LEU LEU A . n 
A 1 148 CYS 148 148 148 CYS CYS A . n 
A 1 149 ALA 149 149 149 ALA ALA A . n 
A 1 150 VAL 150 150 150 VAL VAL A . n 
A 1 151 TRP 151 151 151 TRP TRP A . n 
A 1 152 ILE 152 152 152 ILE ILE A . n 
A 1 153 TYR 153 153 153 TYR TYR A . n 
A 1 154 LEU 154 154 154 LEU LEU A . n 
A 1 155 ASP 155 155 155 ASP ASP A . n 
A 1 156 VAL 156 156 156 VAL VAL A . n 
A 1 157 LEU 157 157 157 LEU LEU A . n 
A 1 158 PHE 158 158 158 PHE PHE A . n 
A 1 159 SER 159 159 159 SER SER A . n 
A 1 160 THR 160 160 160 THR THR A . n 
A 1 161 ALA 161 161 161 ALA ALA A . n 
A 1 162 SER 162 162 162 SER SER A . n 
A 1 163 ILE 163 163 163 ILE ILE A . n 
A 1 164 MET 164 164 164 MET MET A . n 
A 1 165 HIS 165 165 165 HIS HIS A . n 
A 1 166 LEU 166 166 166 LEU LEU A . n 
A 1 167 CYS 167 167 167 CYS CYS A . n 
A 1 168 ALA 168 168 168 ALA ALA A . n 
A 1 169 ILE 169 169 169 ILE ILE A . n 
A 1 170 SER 170 170 170 SER SER A . n 
A 1 171 LEU 171 171 171 LEU LEU A . n 
A 1 172 ASP 172 172 172 ASP ASP A . n 
A 1 173 ARG 173 173 173 ARG ARG A . n 
A 1 174 TYR 174 174 174 TYR TYR A . n 
A 1 175 VAL 175 175 175 VAL VAL A . n 
A 1 176 ALA 176 176 176 ALA ALA A . n 
A 1 177 ILE 177 177 177 ILE ILE A . n 
A 1 178 GLN 178 178 178 GLN GLN A . n 
A 1 179 ASN 179 179 179 ASN ASN A . n 
A 1 180 PRO 180 180 180 PRO PRO A . n 
A 1 181 ILE 181 181 181 ILE ILE A . n 
A 1 182 HIS 182 182 182 HIS HIS A . n 
A 1 183 HIS 183 183 183 HIS HIS A . n 
A 1 184 SER 184 184 184 SER SER A . n 
A 1 185 ARG 185 185 185 ARG ARG A . n 
A 1 186 PHE 186 186 186 PHE PHE A . n 
A 1 187 ASN 187 187 187 ASN ASN A . n 
A 1 188 SER 188 188 188 SER SER A . n 
A 1 189 ARG 189 189 189 ARG ARG A . n 
A 1 190 THR 190 190 190 THR THR A . n 
A 1 191 LYS 191 191 191 LYS LYS A . n 
A 1 192 ALA 192 192 192 ALA ALA A . n 
A 1 193 PHE 193 193 193 PHE PHE A . n 
A 1 194 LEU 194 194 194 LEU LEU A . n 
A 1 195 LYS 195 195 195 LYS LYS A . n 
A 1 196 ILE 196 196 196 ILE ILE A . n 
A 1 197 ILE 197 197 197 ILE ILE A . n 
A 1 198 ALA 198 198 198 ALA ALA A . n 
A 1 199 VAL 199 199 199 VAL VAL A . n 
A 1 200 TRP 200 200 200 TRP TRP A . n 
A 1 201 THR 201 201 201 THR THR A . n 
A 1 202 ILE 202 202 202 ILE ILE A . n 
A 1 203 SER 203 203 203 SER SER A . n 
A 1 204 VAL 204 204 204 VAL VAL A . n 
A 1 205 GLY 205 205 205 GLY GLY A . n 
A 1 206 ILE 206 206 206 ILE ILE A . n 
A 1 207 SER 207 207 207 SER SER A . n 
A 1 208 MET 208 208 208 MET MET A . n 
A 1 209 PRO 209 209 209 PRO PRO A . n 
A 1 210 ILE 210 210 210 ILE ILE A . n 
A 1 211 PRO 211 211 211 PRO PRO A . n 
A 1 212 VAL 212 212 212 VAL VAL A . n 
A 1 213 PHE 213 213 213 PHE PHE A . n 
A 1 214 GLY 214 214 214 GLY GLY A . n 
A 1 215 LEU 215 215 215 LEU LEU A . n 
A 1 216 GLN 216 216 216 GLN GLN A . n 
A 1 217 ASP 217 217 217 ASP ASP A . n 
A 1 218 ASP 218 218 218 ASP ASP A . n 
A 1 219 SER 219 219 219 SER SER A . n 
A 1 220 LYS 220 220 220 LYS LYS A . n 
A 1 221 VAL 221 221 221 VAL VAL A . n 
A 1 222 PHE 222 222 222 PHE PHE A . n 
A 1 223 LYS 223 223 223 LYS LYS A . n 
A 1 224 GLU 224 224 224 GLU GLU A . n 
A 1 225 GLY 225 225 225 GLY GLY A . n 
A 1 226 SER 226 226 226 SER SER A . n 
A 1 227 CYS 227 227 227 CYS CYS A . n 
A 1 228 LEU 228 228 228 LEU LEU A . n 
A 1 229 LEU 229 229 229 LEU LEU A . n 
A 1 230 ALA 230 230 230 ALA ALA A . n 
A 1 231 ASP 231 231 231 ASP ASP A . n 
A 1 232 ASP 232 232 232 ASP ASP A . n 
A 1 233 ASN 233 233 233 ASN ASN A . n 
A 1 234 PHE 234 234 234 PHE PHE A . n 
A 1 235 VAL 235 235 235 VAL VAL A . n 
A 1 236 LEU 236 236 236 LEU LEU A . n 
A 1 237 ILE 237 237 237 ILE ILE A . n 
A 1 238 GLY 238 238 238 GLY GLY A . n 
A 1 239 SER 239 239 239 SER SER A . n 
A 1 240 PHE 240 240 240 PHE PHE A . n 
A 1 241 VAL 241 241 241 VAL VAL A . n 
A 1 242 SER 242 242 242 SER SER A . n 
A 1 243 PHE 243 243 243 PHE PHE A . n 
A 1 244 PHE 244 244 244 PHE PHE A . n 
A 1 245 ILE 245 245 245 ILE ILE A . n 
A 1 246 PRO 246 246 246 PRO PRO A . n 
A 1 247 LEU 247 247 247 LEU LEU A . n 
A 1 248 THR 248 248 248 THR THR A . n 
A 1 249 ILE 249 249 249 ILE ILE A . n 
A 1 250 MET 250 250 250 MET MET A . n 
A 1 251 VAL 251 251 251 VAL VAL A . n 
A 1 252 ILE 252 252 252 ILE ILE A . n 
A 1 253 THR 253 253 253 THR THR A . n 
A 1 254 TYR 254 254 254 TYR TYR A . n 
A 1 255 PHE 255 255 255 PHE PHE A . n 
A 1 256 LEU 256 256 256 LEU LEU A . n 
A 1 257 THR 257 257 257 THR THR A . n 
A 1 258 ILE 258 258 258 ILE ILE A . n 
A 1 259 LYS 259 259 259 LYS LYS A . n 
A 1 260 SER 260 260 260 SER SER A . n 
A 1 261 LEU 261 261 261 LEU LEU A . n 
A 1 262 GLN 262 262 262 GLN GLN A . n 
A 1 263 LYS 263 263 ?   ?   ?   A . n 
A 1 264 GLU 264 264 ?   ?   ?   A . n 
A 1 265 ALA 265 265 ?   ?   ?   A . n 
A 1 266 THR 266 266 ?   ?   ?   A . n 
A 1 267 LEU 267 267 ?   ?   ?   A . n 
A 1 268 CYS 268 268 ?   ?   ?   A . n 
A 1 269 VAL 269 269 ?   ?   ?   A . n 
A 1 270 SER 270 270 ?   ?   ?   A . n 
A 1 271 ASP 271 271 ?   ?   ?   A . n 
A 1 272 LEU 272 272 ?   ?   ?   A . n 
A 1 273 GLY 273 273 ?   ?   ?   A . n 
A 1 274 THR 274 274 ?   ?   ?   A . n 
A 1 275 ARG 275 275 ?   ?   ?   A . n 
A 1 276 ALA 276 276 ?   ?   ?   A . n 
A 1 277 LYS 277 277 ?   ?   ?   A . n 
A 1 278 LEU 278 278 ?   ?   ?   A . n 
A 1 279 ALA 279 279 ?   ?   ?   A . n 
A 1 280 SER 280 280 ?   ?   ?   A . n 
A 1 281 PHE 281 281 ?   ?   ?   A . n 
A 1 282 SER 282 282 ?   ?   ?   A . n 
A 1 283 PHE 283 283 ?   ?   ?   A . n 
A 1 284 LEU 284 284 ?   ?   ?   A . n 
A 1 285 PRO 285 285 ?   ?   ?   A . n 
A 1 286 GLN 286 286 ?   ?   ?   A . n 
A 1 287 SER 287 287 ?   ?   ?   A . n 
A 1 288 SER 288 288 ?   ?   ?   A . n 
A 1 289 LEU 289 289 ?   ?   ?   A . n 
A 1 290 SER 290 290 ?   ?   ?   A . n 
A 1 291 SER 291 291 ?   ?   ?   A . n 
A 1 292 GLU 292 292 ?   ?   ?   A . n 
A 1 293 LYS 293 293 ?   ?   ?   A . n 
A 1 294 LEU 294 294 ?   ?   ?   A . n 
A 1 295 PHE 295 295 ?   ?   ?   A . n 
A 1 296 GLN 296 296 ?   ?   ?   A . n 
A 1 297 ARG 297 297 ?   ?   ?   A . n 
A 1 298 SER 298 298 ?   ?   ?   A . n 
A 1 299 ILE 299 299 ?   ?   ?   A . n 
A 1 300 HIS 300 300 ?   ?   ?   A . n 
A 1 301 ARG 301 301 ?   ?   ?   A . n 
A 1 302 GLU 302 302 ?   ?   ?   A . n 
A 1 303 PRO 303 303 ?   ?   ?   A . n 
A 1 304 GLY 304 304 ?   ?   ?   A . n 
A 1 305 SER 305 305 ?   ?   ?   A . n 
A 1 306 TYR 306 306 ?   ?   ?   A . n 
A 1 307 THR 307 307 ?   ?   ?   A . n 
A 1 308 GLY 308 308 ?   ?   ?   A . n 
A 1 309 ARG 309 309 ?   ?   ?   A . n 
A 1 310 ARG 310 310 ?   ?   ?   A . n 
A 1 311 THR 311 311 ?   ?   ?   A . n 
A 1 312 MET 312 312 ?   ?   ?   A . n 
A 1 313 GLN 313 313 ?   ?   ?   A . n 
A 1 314 SER 314 314 ?   ?   ?   A . n 
A 1 315 ILE 315 315 315 ILE ILE A . n 
A 1 316 SER 316 316 316 SER SER A . n 
A 1 317 ASN 317 317 317 ASN ASN A . n 
A 1 318 GLU 318 318 318 GLU GLU A . n 
A 1 319 GLN 319 319 319 GLN GLN A . n 
A 1 320 LYS 320 320 320 LYS LYS A . n 
A 1 321 ALA 321 321 321 ALA ALA A . n 
A 1 322 CYS 322 322 322 CYS CYS A . n 
A 1 323 LYS 323 323 323 LYS LYS A . n 
A 1 324 VAL 324 324 324 VAL VAL A . n 
A 1 325 LEU 325 325 325 LEU LEU A . n 
A 1 326 GLY 326 326 326 GLY GLY A . n 
A 1 327 ILE 327 327 327 ILE ILE A . n 
A 1 328 VAL 328 328 328 VAL VAL A . n 
A 1 329 PHE 329 329 329 PHE PHE A . n 
A 1 330 PHE 330 330 330 PHE PHE A . n 
A 1 331 LEU 331 331 331 LEU LEU A . n 
A 1 332 PHE 332 332 332 PHE PHE A . n 
A 1 333 VAL 333 333 333 VAL VAL A . n 
A 1 334 VAL 334 334 334 VAL VAL A . n 
A 1 335 MET 335 335 335 MET MET A . n 
A 1 336 TRP 336 336 336 TRP TRP A . n 
A 1 337 CYS 337 337 337 CYS CYS A . n 
A 1 338 PRO 338 338 338 PRO PRO A . n 
A 1 339 PHE 339 339 339 PHE PHE A . n 
A 1 340 PHE 340 340 340 PHE PHE A . n 
A 1 341 ILE 341 341 341 ILE ILE A . n 
A 1 342 THR 342 342 342 THR THR A . n 
A 1 343 ASN 343 343 343 ASN ASN A . n 
A 1 344 ILE 344 344 344 ILE ILE A . n 
A 1 345 MET 345 345 345 MET MET A . n 
A 1 346 ALA 346 346 346 ALA ALA A . n 
A 1 347 VAL 347 347 347 VAL VAL A . n 
A 1 348 ILE 348 348 ?   ?   ?   A . n 
A 1 349 CYS 349 349 ?   ?   ?   A . n 
A 1 350 LYS 350 350 ?   ?   ?   A . n 
A 1 351 GLU 351 351 ?   ?   ?   A . n 
A 1 352 SER 352 352 ?   ?   ?   A . n 
A 1 353 CYS 353 353 ?   ?   ?   A . n 
A 1 354 ASN 354 354 354 ASN ASN A . n 
A 1 355 GLU 355 355 355 GLU GLU A . n 
A 1 356 ASP 356 356 356 ASP ASP A . n 
A 1 357 VAL 357 357 357 VAL VAL A . n 
A 1 358 ILE 358 358 358 ILE ILE A . n 
A 1 359 GLY 359 359 359 GLY GLY A . n 
A 1 360 ALA 360 360 360 ALA ALA A . n 
A 1 361 LEU 361 361 361 LEU LEU A . n 
A 1 362 LEU 362 362 362 LEU LEU A . n 
A 1 363 ASN 363 363 363 ASN ASN A . n 
A 1 364 VAL 364 364 364 VAL VAL A . n 
A 1 365 PHE 365 365 365 PHE PHE A . n 
A 1 366 VAL 366 366 366 VAL VAL A . n 
A 1 367 TRP 367 367 367 TRP TRP A . n 
A 1 368 ILE 368 368 368 ILE ILE A . n 
A 1 369 GLY 369 369 369 GLY GLY A . n 
A 1 370 TYR 370 370 370 TYR TYR A . n 
A 1 371 LEU 371 371 371 LEU LEU A . n 
A 1 372 SER 372 372 372 SER SER A . n 
A 1 373 SER 373 373 373 SER SER A . n 
A 1 374 ALA 374 374 374 ALA ALA A . n 
A 1 375 VAL 375 375 375 VAL VAL A . n 
A 1 376 ASN 376 376 376 ASN ASN A . n 
A 1 377 PRO 377 377 377 PRO PRO A . n 
A 1 378 LEU 378 378 378 LEU LEU A . n 
A 1 379 VAL 379 379 379 VAL VAL A . n 
A 1 380 TYR 380 380 380 TYR TYR A . n 
A 1 381 THR 381 381 381 THR THR A . n 
A 1 382 LEU 382 382 382 LEU LEU A . n 
A 1 383 PHE 383 383 383 PHE PHE A . n 
A 1 384 ASN 384 384 384 ASN ASN A . n 
A 1 385 LYS 385 385 385 LYS LYS A . n 
A 1 386 THR 386 386 386 THR THR A . n 
A 1 387 TYR 387 387 387 TYR TYR A . n 
A 1 388 ARG 388 388 388 ARG ARG A . n 
A 1 389 SER 389 389 389 SER SER A . n 
A 1 390 ALA 390 390 390 ALA ALA A . n 
A 1 391 PHE 391 391 391 PHE PHE A . n 
A 1 392 SER 392 392 392 SER SER A . n 
A 1 393 ARG 393 393 393 ARG ARG A . n 
A 1 394 TYR 394 394 ?   ?   ?   A . n 
A 1 395 ILE 395 395 ?   ?   ?   A . n 
A 1 396 GLN 396 396 ?   ?   ?   A . n 
A 1 397 CYS 397 397 ?   ?   ?   A . n 
A 1 398 GLN 398 398 ?   ?   ?   A . n 
A 1 399 TYR 399 399 ?   ?   ?   A . n 
A 1 400 LYS 400 400 ?   ?   ?   A . n 
A 1 401 GLU 401 401 ?   ?   ?   A . n 
A 1 402 ASN 402 402 ?   ?   ?   A . n 
A 1 403 LYS 403 403 ?   ?   ?   A . n 
A 1 404 LYS 404 404 ?   ?   ?   A . n 
A 1 405 PRO 405 405 ?   ?   ?   A . n 
A 1 406 LEU 406 406 ?   ?   ?   A . n 
A 1 407 GLN 407 407 ?   ?   ?   A . n 
A 1 408 LEU 408 408 ?   ?   ?   A . n 
A 1 409 ILE 409 409 ?   ?   ?   A . n 
A 1 410 LEU 410 410 ?   ?   ?   A . n 
A 1 411 VAL 411 411 ?   ?   ?   A . n 
A 1 412 ASN 412 412 ?   ?   ?   A . n 
A 1 413 THR 413 413 ?   ?   ?   A . n 
A 1 414 ILE 414 414 ?   ?   ?   A . n 
A 1 415 PRO 415 415 ?   ?   ?   A . n 
A 1 416 ALA 416 416 ?   ?   ?   A . n 
A 1 417 LEU 417 417 ?   ?   ?   A . n 
A 1 418 ALA 418 418 ?   ?   ?   A . n 
A 1 419 TYR 419 419 ?   ?   ?   A . n 
A 1 420 LYS 420 420 ?   ?   ?   A . n 
A 1 421 SER 421 421 ?   ?   ?   A . n 
A 1 422 SER 422 422 ?   ?   ?   A . n 
A 1 423 GLN 423 423 ?   ?   ?   A . n 
A 1 424 LEU 424 424 ?   ?   ?   A . n 
A 1 425 GLN 425 425 ?   ?   ?   A . n 
A 1 426 MET 426 426 ?   ?   ?   A . n 
A 1 427 GLY 427 427 ?   ?   ?   A . n 
A 1 428 GLN 428 428 ?   ?   ?   A . n 
A 1 429 LYS 429 429 ?   ?   ?   A . n 
A 1 430 LYS 430 430 ?   ?   ?   A . n 
A 1 431 ASN 431 431 ?   ?   ?   A . n 
A 1 432 SER 432 432 ?   ?   ?   A . n 
A 1 433 LYS 433 433 ?   ?   ?   A . n 
A 1 434 GLN 434 434 ?   ?   ?   A . n 
A 1 435 ASP 435 435 ?   ?   ?   A . n 
A 1 436 ALA 436 436 ?   ?   ?   A . n 
A 1 437 LYS 437 437 ?   ?   ?   A . n 
A 1 438 THR 438 438 ?   ?   ?   A . n 
A 1 439 THR 439 439 ?   ?   ?   A . n 
A 1 440 ASP 440 440 ?   ?   ?   A . n 
A 1 441 ASN 441 441 ?   ?   ?   A . n 
A 1 442 ASP 442 442 ?   ?   ?   A . n 
A 1 443 CYS 443 443 ?   ?   ?   A . n 
A 1 444 SER 444 444 ?   ?   ?   A . n 
A 1 445 MET 445 445 ?   ?   ?   A . n 
A 1 446 VAL 446 446 ?   ?   ?   A . n 
A 1 447 ALA 447 447 ?   ?   ?   A . n 
A 1 448 LEU 448 448 ?   ?   ?   A . n 
A 1 449 GLY 449 449 ?   ?   ?   A . n 
A 1 450 LYS 450 450 ?   ?   ?   A . n 
A 1 451 GLN 451 451 ?   ?   ?   A . n 
A 1 452 HIS 452 452 ?   ?   ?   A . n 
A 1 453 SER 453 453 ?   ?   ?   A . n 
A 1 454 GLU 454 454 ?   ?   ?   A . n 
A 1 455 GLU 455 455 ?   ?   ?   A . n 
A 1 456 ALA 456 456 ?   ?   ?   A . n 
A 1 457 SER 457 457 ?   ?   ?   A . n 
A 1 458 LYS 458 458 ?   ?   ?   A . n 
A 1 459 ASP 459 459 ?   ?   ?   A . n 
A 1 460 ASN 460 460 ?   ?   ?   A . n 
A 1 461 SER 461 461 ?   ?   ?   A . n 
A 1 462 ASP 462 462 ?   ?   ?   A . n 
A 1 463 GLY 463 463 ?   ?   ?   A . n 
A 1 464 VAL 464 464 ?   ?   ?   A . n 
A 1 465 ASN 465 465 ?   ?   ?   A . n 
A 1 466 GLU 466 466 ?   ?   ?   A . n 
A 1 467 LYS 467 467 ?   ?   ?   A . n 
A 1 468 VAL 468 468 ?   ?   ?   A . n 
A 1 469 SER 469 469 ?   ?   ?   A . n 
A 1 470 CYS 470 470 ?   ?   ?   A . n 
A 1 471 VAL 471 471 ?   ?   ?   A . n 
B 2 1   MET 1   1   ?   ?   ?   B . n 
B 2 2   GLY 2   2   ?   ?   ?   B . n 
B 2 3   SER 3   3   ?   ?   ?   B . n 
B 2 4   THR 4   4   4   THR THR B . n 
B 2 5   VAL 5   5   5   VAL VAL B . n 
B 2 6   SER 6   6   6   SER SER B . n 
B 2 7   ALA 7   7   7   ALA ALA B . n 
B 2 8   GLU 8   8   8   GLU GLU B . n 
B 2 9   ASP 9   9   9   ASP ASP B . n 
B 2 10  LYS 10  10  10  LYS LYS B . n 
B 2 11  ALA 11  11  11  ALA ALA B . n 
B 2 12  ALA 12  12  12  ALA ALA B . n 
B 2 13  ALA 13  13  13  ALA ALA B . n 
B 2 14  GLU 14  14  14  GLU GLU B . n 
B 2 15  ARG 15  15  15  ARG ARG B . n 
B 2 16  SER 16  16  16  SER SER B . n 
B 2 17  LYS 17  17  17  LYS LYS B . n 
B 2 18  MET 18  18  18  MET MET B . n 
B 2 19  ILE 19  19  19  ILE ILE B . n 
B 2 20  ASP 20  20  20  ASP ASP B . n 
B 2 21  LYS 21  21  21  LYS LYS B . n 
B 2 22  ASN 22  22  22  ASN ASN B . n 
B 2 23  LEU 23  23  23  LEU LEU B . n 
B 2 24  ARG 24  24  24  ARG ARG B . n 
B 2 25  GLU 25  25  25  GLU GLU B . n 
B 2 26  ASP 26  26  26  ASP ASP B . n 
B 2 27  GLY 27  27  27  GLY GLY B . n 
B 2 28  GLU 28  28  28  GLU GLU B . n 
B 2 29  LYS 29  29  29  LYS LYS B . n 
B 2 30  ALA 30  30  30  ALA ALA B . n 
B 2 31  ARG 31  31  31  ARG ARG B . n 
B 2 32  ARG 32  32  32  ARG ARG B . n 
B 2 33  THR 33  33  33  THR THR B . n 
B 2 34  LEU 34  34  34  LEU LEU B . n 
B 2 35  ARG 35  35  35  ARG ARG B . n 
B 2 36  LEU 36  36  36  LEU LEU B . n 
B 2 37  LEU 37  37  37  LEU LEU B . n 
B 2 38  LEU 38  38  38  LEU LEU B . n 
B 2 39  LEU 39  39  39  LEU LEU B . n 
B 2 40  GLY 40  40  40  GLY GLY B . n 
B 2 41  ALA 41  41  41  ALA ALA B . n 
B 2 42  ASP 42  42  42  ASP ASP B . n 
B 2 43  ASN 43  43  43  ASN ASN B . n 
B 2 44  SER 44  44  44  SER SER B . n 
B 2 45  GLY 45  45  45  GLY GLY B . n 
B 2 46  LYS 46  46  46  LYS LYS B . n 
B 2 47  SER 47  47  47  SER SER B . n 
B 2 48  THR 48  48  48  THR THR B . n 
B 2 49  ILE 49  49  49  ILE ILE B . n 
B 2 50  VAL 50  50  50  VAL VAL B . n 
B 2 51  LYS 51  51  51  LYS LYS B . n 
B 2 52  GLN 52  52  52  GLN GLN B . n 
B 2 53  MET 53  53  53  MET MET B . n 
B 2 54  ARG 54  54  54  ARG ARG B . n 
B 2 55  ILE 55  55  ?   ?   ?   B . n 
B 2 56  LEU 56  56  ?   ?   ?   B . n 
B 2 57  HIS 57  57  ?   ?   ?   B . n 
B 2 58  GLY 58  58  ?   ?   ?   B . n 
B 2 59  GLY 59  59  ?   ?   ?   B . n 
B 2 60  SER 60  60  ?   ?   ?   B . n 
B 2 61  GLY 61  61  ?   ?   ?   B . n 
B 2 62  GLY 62  62  ?   ?   ?   B . n 
B 2 63  SER 63  63  ?   ?   ?   B . n 
B 2 64  GLY 64  64  ?   ?   ?   B . n 
B 2 65  GLY 65  65  ?   ?   ?   B . n 
B 2 66  THR 66  66  66  THR THR B . n 
B 2 67  SER 67  67  67  SER SER B . n 
B 2 68  GLY 68  68  68  GLY GLY B . n 
B 2 69  ILE 69  69  69  ILE ILE B . n 
B 2 70  PHE 70  70  70  PHE PHE B . n 
B 2 71  GLU 71  71  71  GLU GLU B . n 
B 2 72  THR 72  72  72  THR THR B . n 
B 2 73  LYS 73  73  73  LYS LYS B . n 
B 2 74  PHE 74  74  74  PHE PHE B . n 
B 2 75  GLN 75  75  75  GLN GLN B . n 
B 2 76  VAL 76  76  76  VAL VAL B . n 
B 2 77  ASP 77  77  77  ASP ASP B . n 
B 2 78  LYS 78  78  78  LYS LYS B . n 
B 2 79  VAL 79  79  79  VAL VAL B . n 
B 2 80  ASN 80  80  80  ASN ASN B . n 
B 2 81  PHE 81  81  81  PHE PHE B . n 
B 2 82  HIS 82  82  82  HIS HIS B . n 
B 2 83  MET 83  83  83  MET MET B . n 
B 2 84  PHE 84  84  84  PHE PHE B . n 
B 2 85  ASP 85  85  85  ASP ASP B . n 
B 2 86  VAL 86  86  86  VAL VAL B . n 
B 2 87  GLY 87  87  87  GLY GLY B . n 
B 2 88  GLY 88  88  88  GLY GLY B . n 
B 2 89  GLN 89  89  89  GLN GLN B . n 
B 2 90  ARG 90  90  90  ARG ARG B . n 
B 2 91  ASP 91  91  91  ASP ASP B . n 
B 2 92  GLU 92  92  92  GLU GLU B . n 
B 2 93  ARG 93  93  93  ARG ARG B . n 
B 2 94  ARG 94  94  94  ARG ARG B . n 
B 2 95  LYS 95  95  95  LYS LYS B . n 
B 2 96  TRP 96  96  96  TRP TRP B . n 
B 2 97  ILE 97  97  97  ILE ILE B . n 
B 2 98  GLN 98  98  98  GLN GLN B . n 
B 2 99  CYS 99  99  99  CYS CYS B . n 
B 2 100 PHE 100 100 100 PHE PHE B . n 
B 2 101 ASN 101 101 101 ASN ASN B . n 
B 2 102 ASP 102 102 102 ASP ASP B . n 
B 2 103 VAL 103 103 103 VAL VAL B . n 
B 2 104 THR 104 104 104 THR THR B . n 
B 2 105 ALA 105 105 105 ALA ALA B . n 
B 2 106 ILE 106 106 106 ILE ILE B . n 
B 2 107 ILE 107 107 107 ILE ILE B . n 
B 2 108 PHE 108 108 108 PHE PHE B . n 
B 2 109 VAL 109 109 109 VAL VAL B . n 
B 2 110 VAL 110 110 110 VAL VAL B . n 
B 2 111 ASP 111 111 111 ASP ASP B . n 
B 2 112 SER 112 112 112 SER SER B . n 
B 2 113 SER 113 113 113 SER SER B . n 
B 2 114 ASP 114 114 114 ASP ASP B . n 
B 2 115 TYR 115 115 115 TYR TYR B . n 
B 2 116 ASN 116 116 116 ASN ASN B . n 
B 2 117 ARG 117 117 117 ARG ARG B . n 
B 2 118 LEU 118 118 118 LEU LEU B . n 
B 2 119 GLN 119 119 119 GLN GLN B . n 
B 2 120 GLU 120 120 120 GLU GLU B . n 
B 2 121 ALA 121 121 121 ALA ALA B . n 
B 2 122 LEU 122 122 122 LEU LEU B . n 
B 2 123 ASN 123 123 123 ASN ASN B . n 
B 2 124 ASP 124 124 124 ASP ASP B . n 
B 2 125 PHE 125 125 125 PHE PHE B . n 
B 2 126 LYS 126 126 126 LYS LYS B . n 
B 2 127 SER 127 127 127 SER SER B . n 
B 2 128 ILE 128 128 128 ILE ILE B . n 
B 2 129 TRP 129 129 129 TRP TRP B . n 
B 2 130 ASN 130 130 130 ASN ASN B . n 
B 2 131 ASN 131 131 131 ASN ASN B . n 
B 2 132 ARG 132 132 132 ARG ARG B . n 
B 2 133 TRP 133 133 133 TRP TRP B . n 
B 2 134 LEU 134 134 134 LEU LEU B . n 
B 2 135 ARG 135 135 135 ARG ARG B . n 
B 2 136 THR 136 136 136 THR THR B . n 
B 2 137 ILE 137 137 137 ILE ILE B . n 
B 2 138 SER 138 138 138 SER SER B . n 
B 2 139 VAL 139 139 139 VAL VAL B . n 
B 2 140 ILE 140 140 140 ILE ILE B . n 
B 2 141 LEU 141 141 141 LEU LEU B . n 
B 2 142 PHE 142 142 142 PHE PHE B . n 
B 2 143 LEU 143 143 143 LEU LEU B . n 
B 2 144 ASN 144 144 144 ASN ASN B . n 
B 2 145 LYS 145 145 145 LYS LYS B . n 
B 2 146 GLN 146 146 146 GLN GLN B . n 
B 2 147 ASP 147 147 147 ASP ASP B . n 
B 2 148 LEU 148 148 148 LEU LEU B . n 
B 2 149 LEU 149 149 149 LEU LEU B . n 
B 2 150 ALA 150 150 150 ALA ALA B . n 
B 2 151 GLU 151 151 151 GLU GLU B . n 
B 2 152 LYS 152 152 152 LYS LYS B . n 
B 2 153 VAL 153 153 153 VAL VAL B . n 
B 2 154 LEU 154 154 154 LEU LEU B . n 
B 2 155 ALA 155 155 155 ALA ALA B . n 
B 2 156 GLY 156 156 156 GLY GLY B . n 
B 2 157 LYS 157 157 157 LYS LYS B . n 
B 2 158 SER 158 158 158 SER SER B . n 
B 2 159 LYS 159 159 159 LYS LYS B . n 
B 2 160 ILE 160 160 160 ILE ILE B . n 
B 2 161 GLU 161 161 161 GLU GLU B . n 
B 2 162 ASP 162 162 162 ASP ASP B . n 
B 2 163 TYR 163 163 163 TYR TYR B . n 
B 2 164 PHE 164 164 164 PHE PHE B . n 
B 2 165 PRO 165 165 165 PRO PRO B . n 
B 2 166 GLU 166 166 166 GLU GLU B . n 
B 2 167 PHE 167 167 167 PHE PHE B . n 
B 2 168 ALA 168 168 168 ALA ALA B . n 
B 2 169 ARG 169 169 169 ARG ARG B . n 
B 2 170 TYR 170 170 170 TYR TYR B . n 
B 2 171 THR 171 171 171 THR THR B . n 
B 2 172 THR 172 172 172 THR THR B . n 
B 2 173 PRO 173 173 173 PRO PRO B . n 
B 2 174 GLU 174 174 ?   ?   ?   B . n 
B 2 175 ASP 175 175 ?   ?   ?   B . n 
B 2 176 ALA 176 176 ?   ?   ?   B . n 
B 2 177 THR 177 177 ?   ?   ?   B . n 
B 2 178 PRO 178 178 ?   ?   ?   B . n 
B 2 179 GLU 179 179 ?   ?   ?   B . n 
B 2 180 PRO 180 180 ?   ?   ?   B . n 
B 2 181 GLY 181 181 ?   ?   ?   B . n 
B 2 182 GLU 182 182 182 GLU GLU B . n 
B 2 183 ASP 183 183 183 ASP ASP B . n 
B 2 184 PRO 184 184 184 PRO PRO B . n 
B 2 185 ARG 185 185 185 ARG ARG B . n 
B 2 186 VAL 186 186 186 VAL VAL B . n 
B 2 187 THR 187 187 187 THR THR B . n 
B 2 188 ARG 188 188 188 ARG ARG B . n 
B 2 189 ALA 189 189 189 ALA ALA B . n 
B 2 190 LYS 190 190 190 LYS LYS B . n 
B 2 191 TYR 191 191 191 TYR TYR B . n 
B 2 192 PHE 192 192 192 PHE PHE B . n 
B 2 193 ILE 193 193 193 ILE ILE B . n 
B 2 194 ARG 194 194 194 ARG ARG B . n 
B 2 195 LYS 195 195 195 LYS LYS B . n 
B 2 196 GLU 196 196 196 GLU GLU B . n 
B 2 197 PHE 197 197 197 PHE PHE B . n 
B 2 198 VAL 198 198 198 VAL VAL B . n 
B 2 199 ASP 199 199 199 ASP ASP B . n 
B 2 200 ILE 200 200 200 ILE ILE B . n 
B 2 201 SER 201 201 201 SER SER B . n 
B 2 202 THR 202 202 202 THR THR B . n 
B 2 203 ALA 203 203 203 ALA ALA B . n 
B 2 204 SER 204 204 204 SER SER B . n 
B 2 205 GLY 205 205 205 GLY GLY B . n 
B 2 206 ASP 206 206 206 ASP ASP B . n 
B 2 207 GLY 207 207 207 GLY GLY B . n 
B 2 208 ARG 208 208 208 ARG ARG B . n 
B 2 209 HIS 209 209 209 HIS HIS B . n 
B 2 210 ILE 210 210 210 ILE ILE B . n 
B 2 211 CYS 211 211 211 CYS CYS B . n 
B 2 212 TYR 212 212 212 TYR TYR B . n 
B 2 213 PRO 213 213 213 PRO PRO B . n 
B 2 214 HIS 214 214 214 HIS HIS B . n 
B 2 215 PHE 215 215 215 PHE PHE B . n 
B 2 216 THR 216 216 216 THR THR B . n 
B 2 217 CYS 217 217 217 CYS CYS B . n 
B 2 218 ALA 218 218 218 ALA ALA B . n 
B 2 219 VAL 219 219 219 VAL VAL B . n 
B 2 220 ASP 220 220 220 ASP ASP B . n 
B 2 221 THR 221 221 221 THR THR B . n 
B 2 222 GLU 222 222 222 GLU GLU B . n 
B 2 223 ASN 223 223 223 ASN ASN B . n 
B 2 224 ALA 224 224 224 ALA ALA B . n 
B 2 225 ARG 225 225 225 ARG ARG B . n 
B 2 226 ARG 226 226 226 ARG ARG B . n 
B 2 227 ILE 227 227 227 ILE ILE B . n 
B 2 228 PHE 228 228 228 PHE PHE B . n 
B 2 229 ASN 229 229 229 ASN ASN B . n 
B 2 230 ASP 230 230 230 ASP ASP B . n 
B 2 231 CYS 231 231 231 CYS CYS B . n 
B 2 232 LYS 232 232 232 LYS LYS B . n 
B 2 233 ASP 233 233 233 ASP ASP B . n 
B 2 234 ILE 234 234 234 ILE ILE B . n 
B 2 235 ILE 235 235 235 ILE ILE B . n 
B 2 236 LEU 236 236 236 LEU LEU B . n 
B 2 237 GLN 237 237 237 GLN GLN B . n 
B 2 238 MET 238 238 238 MET MET B . n 
B 2 239 ASN 239 239 239 ASN ASN B . n 
B 2 240 LEU 240 240 240 LEU LEU B . n 
B 2 241 ARG 241 241 241 ARG ARG B . n 
B 2 242 GLU 242 242 242 GLU GLU B . n 
B 2 243 TYR 243 243 243 TYR TYR B . n 
B 2 244 ASN 244 244 244 ASN ASN B . n 
B 2 245 LEU 245 245 245 LEU LEU B . n 
B 2 246 VAL 246 246 246 VAL VAL B . n 
C 3 1   MET 1   -17 ?   ?   ?   C . n 
C 3 2   HIS 2   -16 ?   ?   ?   C . n 
C 3 3   HIS 3   -15 ?   ?   ?   C . n 
C 3 4   HIS 4   -14 ?   ?   ?   C . n 
C 3 5   HIS 5   -13 ?   ?   ?   C . n 
C 3 6   HIS 6   -12 ?   ?   ?   C . n 
C 3 7   HIS 7   -11 ?   ?   ?   C . n 
C 3 8   LEU 8   -10 ?   ?   ?   C . n 
C 3 9   GLU 9   -9  ?   ?   ?   C . n 
C 3 10  VAL 10  -8  ?   ?   ?   C . n 
C 3 11  LEU 11  -7  ?   ?   ?   C . n 
C 3 12  PHE 12  -6  ?   ?   ?   C . n 
C 3 13  GLN 13  -5  ?   ?   ?   C . n 
C 3 14  GLY 14  -4  ?   ?   ?   C . n 
C 3 15  PRO 15  -3  ?   ?   ?   C . n 
C 3 16  GLY 16  -2  ?   ?   ?   C . n 
C 3 17  SER 17  -1  ?   ?   ?   C . n 
C 3 18  SER 18  0   ?   ?   ?   C . n 
C 3 19  GLY 19  1   ?   ?   ?   C . n 
C 3 20  SER 20  2   ?   ?   ?   C . n 
C 3 21  GLU 21  3   ?   ?   ?   C . n 
C 3 22  LEU 22  4   ?   ?   ?   C . n 
C 3 23  ASP 23  5   ?   ?   ?   C . n 
C 3 24  GLN 24  6   ?   ?   ?   C . n 
C 3 25  LEU 25  7   ?   ?   ?   C . n 
C 3 26  ARG 26  8   ?   ?   ?   C . n 
C 3 27  GLN 27  9   ?   ?   ?   C . n 
C 3 28  GLU 28  10  10  GLU GLU C . n 
C 3 29  ALA 29  11  11  ALA ALA C . n 
C 3 30  GLU 30  12  12  GLU GLU C . n 
C 3 31  GLN 31  13  13  GLN GLN C . n 
C 3 32  LEU 32  14  14  LEU LEU C . n 
C 3 33  LYS 33  15  15  LYS LYS C . n 
C 3 34  ASN 34  16  16  ASN ASN C . n 
C 3 35  GLN 35  17  17  GLN GLN C . n 
C 3 36  ILE 36  18  18  ILE ILE C . n 
C 3 37  ARG 37  19  19  ARG ARG C . n 
C 3 38  ASP 38  20  20  ASP ASP C . n 
C 3 39  ALA 39  21  21  ALA ALA C . n 
C 3 40  ARG 40  22  22  ARG ARG C . n 
C 3 41  LYS 41  23  23  LYS LYS C . n 
C 3 42  ALA 42  24  24  ALA ALA C . n 
C 3 43  CYS 43  25  25  CYS CYS C . n 
C 3 44  ALA 44  26  26  ALA ALA C . n 
C 3 45  ASP 45  27  27  ASP ASP C . n 
C 3 46  ALA 46  28  28  ALA ALA C . n 
C 3 47  THR 47  29  29  THR THR C . n 
C 3 48  LEU 48  30  30  LEU LEU C . n 
C 3 49  SER 49  31  31  SER SER C . n 
C 3 50  GLN 50  32  32  GLN GLN C . n 
C 3 51  ILE 51  33  33  ILE ILE C . n 
C 3 52  THR 52  34  34  THR THR C . n 
C 3 53  ASN 53  35  35  ASN ASN C . n 
C 3 54  ASN 54  36  36  ASN ASN C . n 
C 3 55  ILE 55  37  37  ILE ILE C . n 
C 3 56  ASP 56  38  38  ASP ASP C . n 
C 3 57  PRO 57  39  39  PRO PRO C . n 
C 3 58  VAL 58  40  40  VAL VAL C . n 
C 3 59  GLY 59  41  41  GLY GLY C . n 
C 3 60  ARG 60  42  42  ARG ARG C . n 
C 3 61  ILE 61  43  43  ILE ILE C . n 
C 3 62  GLN 62  44  44  GLN GLN C . n 
C 3 63  MET 63  45  45  MET MET C . n 
C 3 64  ARG 64  46  46  ARG ARG C . n 
C 3 65  THR 65  47  47  THR THR C . n 
C 3 66  ARG 66  48  48  ARG ARG C . n 
C 3 67  ARG 67  49  49  ARG ARG C . n 
C 3 68  THR 68  50  50  THR THR C . n 
C 3 69  LEU 69  51  51  LEU LEU C . n 
C 3 70  ARG 70  52  52  ARG ARG C . n 
C 3 71  GLY 71  53  53  GLY GLY C . n 
C 3 72  HIS 72  54  54  HIS HIS C . n 
C 3 73  LEU 73  55  55  LEU LEU C . n 
C 3 74  ALA 74  56  56  ALA ALA C . n 
C 3 75  LYS 75  57  57  LYS LYS C . n 
C 3 76  ILE 76  58  58  ILE ILE C . n 
C 3 77  TYR 77  59  59  TYR TYR C . n 
C 3 78  ALA 78  60  60  ALA ALA C . n 
C 3 79  MET 79  61  61  MET MET C . n 
C 3 80  HIS 80  62  62  HIS HIS C . n 
C 3 81  TRP 81  63  63  TRP TRP C . n 
C 3 82  GLY 82  64  64  GLY GLY C . n 
C 3 83  THR 83  65  65  THR THR C . n 
C 3 84  ASP 84  66  66  ASP ASP C . n 
C 3 85  SER 85  67  67  SER SER C . n 
C 3 86  ARG 86  68  68  ARG ARG C . n 
C 3 87  LEU 87  69  69  LEU LEU C . n 
C 3 88  LEU 88  70  70  LEU LEU C . n 
C 3 89  VAL 89  71  71  VAL VAL C . n 
C 3 90  SER 90  72  72  SER SER C . n 
C 3 91  ALA 91  73  73  ALA ALA C . n 
C 3 92  SER 92  74  74  SER SER C . n 
C 3 93  GLN 93  75  75  GLN GLN C . n 
C 3 94  ASP 94  76  76  ASP ASP C . n 
C 3 95  GLY 95  77  77  GLY GLY C . n 
C 3 96  LYS 96  78  78  LYS LYS C . n 
C 3 97  LEU 97  79  79  LEU LEU C . n 
C 3 98  ILE 98  80  80  ILE ILE C . n 
C 3 99  ILE 99  81  81  ILE ILE C . n 
C 3 100 TRP 100 82  82  TRP TRP C . n 
C 3 101 ASP 101 83  83  ASP ASP C . n 
C 3 102 SER 102 84  84  SER SER C . n 
C 3 103 TYR 103 85  85  TYR TYR C . n 
C 3 104 THR 104 86  86  THR THR C . n 
C 3 105 THR 105 87  87  THR THR C . n 
C 3 106 ASN 106 88  88  ASN ASN C . n 
C 3 107 LYS 107 89  89  LYS LYS C . n 
C 3 108 VAL 108 90  90  VAL VAL C . n 
C 3 109 HIS 109 91  91  HIS HIS C . n 
C 3 110 ALA 110 92  92  ALA ALA C . n 
C 3 111 ILE 111 93  93  ILE ILE C . n 
C 3 112 PRO 112 94  94  PRO PRO C . n 
C 3 113 LEU 113 95  95  LEU LEU C . n 
C 3 114 ARG 114 96  96  ARG ARG C . n 
C 3 115 SER 115 97  97  SER SER C . n 
C 3 116 SER 116 98  98  SER SER C . n 
C 3 117 TRP 117 99  99  TRP TRP C . n 
C 3 118 VAL 118 100 100 VAL VAL C . n 
C 3 119 MET 119 101 101 MET MET C . n 
C 3 120 THR 120 102 102 THR THR C . n 
C 3 121 CYS 121 103 103 CYS CYS C . n 
C 3 122 ALA 122 104 104 ALA ALA C . n 
C 3 123 TYR 123 105 105 TYR TYR C . n 
C 3 124 ALA 124 106 106 ALA ALA C . n 
C 3 125 PRO 125 107 107 PRO PRO C . n 
C 3 126 SER 126 108 108 SER SER C . n 
C 3 127 GLY 127 109 109 GLY GLY C . n 
C 3 128 ASN 128 110 110 ASN ASN C . n 
C 3 129 TYR 129 111 111 TYR TYR C . n 
C 3 130 VAL 130 112 112 VAL VAL C . n 
C 3 131 ALA 131 113 113 ALA ALA C . n 
C 3 132 CYS 132 114 114 CYS CYS C . n 
C 3 133 GLY 133 115 115 GLY GLY C . n 
C 3 134 GLY 134 116 116 GLY GLY C . n 
C 3 135 LEU 135 117 117 LEU LEU C . n 
C 3 136 ASP 136 118 118 ASP ASP C . n 
C 3 137 ASN 137 119 119 ASN ASN C . n 
C 3 138 ILE 138 120 120 ILE ILE C . n 
C 3 139 CYS 139 121 121 CYS CYS C . n 
C 3 140 SER 140 122 122 SER SER C . n 
C 3 141 ILE 141 123 123 ILE ILE C . n 
C 3 142 TYR 142 124 124 TYR TYR C . n 
C 3 143 ASN 143 125 125 ASN ASN C . n 
C 3 144 LEU 144 126 126 LEU LEU C . n 
C 3 145 LYS 145 127 127 LYS LYS C . n 
C 3 146 THR 146 128 128 THR THR C . n 
C 3 147 ARG 147 129 129 ARG ARG C . n 
C 3 148 GLU 148 130 130 GLU GLU C . n 
C 3 149 GLY 149 131 131 GLY GLY C . n 
C 3 150 ASN 150 132 132 ASN ASN C . n 
C 3 151 VAL 151 133 133 VAL VAL C . n 
C 3 152 ARG 152 134 134 ARG ARG C . n 
C 3 153 VAL 153 135 135 VAL VAL C . n 
C 3 154 SER 154 136 136 SER SER C . n 
C 3 155 ARG 155 137 137 ARG ARG C . n 
C 3 156 GLU 156 138 138 GLU GLU C . n 
C 3 157 LEU 157 139 139 LEU LEU C . n 
C 3 158 ALA 158 140 140 ALA ALA C . n 
C 3 159 GLY 159 141 141 GLY GLY C . n 
C 3 160 HIS 160 142 142 HIS HIS C . n 
C 3 161 THR 161 143 143 THR THR C . n 
C 3 162 GLY 162 144 144 GLY GLY C . n 
C 3 163 TYR 163 145 145 TYR TYR C . n 
C 3 164 LEU 164 146 146 LEU LEU C . n 
C 3 165 SER 165 147 147 SER SER C . n 
C 3 166 CYS 166 148 148 CYS CYS C . n 
C 3 167 CYS 167 149 149 CYS CYS C . n 
C 3 168 ARG 168 150 150 ARG ARG C . n 
C 3 169 PHE 169 151 151 PHE PHE C . n 
C 3 170 LEU 170 152 152 LEU LEU C . n 
C 3 171 ASP 171 153 153 ASP ASP C . n 
C 3 172 ASP 172 154 154 ASP ASP C . n 
C 3 173 ASN 173 155 155 ASN ASN C . n 
C 3 174 GLN 174 156 156 GLN GLN C . n 
C 3 175 ILE 175 157 157 ILE ILE C . n 
C 3 176 VAL 176 158 158 VAL VAL C . n 
C 3 177 THR 177 159 159 THR THR C . n 
C 3 178 SER 178 160 160 SER SER C . n 
C 3 179 SER 179 161 161 SER SER C . n 
C 3 180 GLY 180 162 162 GLY GLY C . n 
C 3 181 ASP 181 163 163 ASP ASP C . n 
C 3 182 THR 182 164 164 THR THR C . n 
C 3 183 THR 183 165 165 THR THR C . n 
C 3 184 CYS 184 166 166 CYS CYS C . n 
C 3 185 ALA 185 167 167 ALA ALA C . n 
C 3 186 LEU 186 168 168 LEU LEU C . n 
C 3 187 TRP 187 169 169 TRP TRP C . n 
C 3 188 ASP 188 170 170 ASP ASP C . n 
C 3 189 ILE 189 171 171 ILE ILE C . n 
C 3 190 GLU 190 172 172 GLU GLU C . n 
C 3 191 THR 191 173 173 THR THR C . n 
C 3 192 GLY 192 174 174 GLY GLY C . n 
C 3 193 GLN 193 175 175 GLN GLN C . n 
C 3 194 GLN 194 176 176 GLN GLN C . n 
C 3 195 THR 195 177 177 THR THR C . n 
C 3 196 THR 196 178 178 THR THR C . n 
C 3 197 THR 197 179 179 THR THR C . n 
C 3 198 PHE 198 180 180 PHE PHE C . n 
C 3 199 THR 199 181 181 THR THR C . n 
C 3 200 GLY 200 182 182 GLY GLY C . n 
C 3 201 HIS 201 183 183 HIS HIS C . n 
C 3 202 THR 202 184 184 THR THR C . n 
C 3 203 GLY 203 185 185 GLY GLY C . n 
C 3 204 ASP 204 186 186 ASP ASP C . n 
C 3 205 VAL 205 187 187 VAL VAL C . n 
C 3 206 MET 206 188 188 MET MET C . n 
C 3 207 SER 207 189 189 SER SER C . n 
C 3 208 LEU 208 190 190 LEU LEU C . n 
C 3 209 SER 209 191 191 SER SER C . n 
C 3 210 LEU 210 192 192 LEU LEU C . n 
C 3 211 ALA 211 193 193 ALA ALA C . n 
C 3 212 PRO 212 194 194 PRO PRO C . n 
C 3 213 ASP 213 195 195 ASP ASP C . n 
C 3 214 THR 214 196 196 THR THR C . n 
C 3 215 ARG 215 197 197 ARG ARG C . n 
C 3 216 LEU 216 198 198 LEU LEU C . n 
C 3 217 PHE 217 199 199 PHE PHE C . n 
C 3 218 VAL 218 200 200 VAL VAL C . n 
C 3 219 SER 219 201 201 SER SER C . n 
C 3 220 GLY 220 202 202 GLY GLY C . n 
C 3 221 ALA 221 203 203 ALA ALA C . n 
C 3 222 CYS 222 204 204 CYS CYS C . n 
C 3 223 ASP 223 205 205 ASP ASP C . n 
C 3 224 ALA 224 206 206 ALA ALA C . n 
C 3 225 SER 225 207 207 SER SER C . n 
C 3 226 ALA 226 208 208 ALA ALA C . n 
C 3 227 LYS 227 209 209 LYS LYS C . n 
C 3 228 LEU 228 210 210 LEU LEU C . n 
C 3 229 TRP 229 211 211 TRP TRP C . n 
C 3 230 ASP 230 212 212 ASP ASP C . n 
C 3 231 VAL 231 213 213 VAL VAL C . n 
C 3 232 ARG 232 214 214 ARG ARG C . n 
C 3 233 GLU 233 215 215 GLU GLU C . n 
C 3 234 GLY 234 216 216 GLY GLY C . n 
C 3 235 MET 235 217 217 MET MET C . n 
C 3 236 CYS 236 218 218 CYS CYS C . n 
C 3 237 ARG 237 219 219 ARG ARG C . n 
C 3 238 GLN 238 220 220 GLN GLN C . n 
C 3 239 THR 239 221 221 THR THR C . n 
C 3 240 PHE 240 222 222 PHE PHE C . n 
C 3 241 THR 241 223 223 THR THR C . n 
C 3 242 GLY 242 224 224 GLY GLY C . n 
C 3 243 HIS 243 225 225 HIS HIS C . n 
C 3 244 GLU 244 226 226 GLU GLU C . n 
C 3 245 SER 245 227 227 SER SER C . n 
C 3 246 ASP 246 228 228 ASP ASP C . n 
C 3 247 ILE 247 229 229 ILE ILE C . n 
C 3 248 ASN 248 230 230 ASN ASN C . n 
C 3 249 ALA 249 231 231 ALA ALA C . n 
C 3 250 ILE 250 232 232 ILE ILE C . n 
C 3 251 CYS 251 233 233 CYS CYS C . n 
C 3 252 PHE 252 234 234 PHE PHE C . n 
C 3 253 PHE 253 235 235 PHE PHE C . n 
C 3 254 PRO 254 236 236 PRO PRO C . n 
C 3 255 ASN 255 237 237 ASN ASN C . n 
C 3 256 GLY 256 238 238 GLY GLY C . n 
C 3 257 ASN 257 239 239 ASN ASN C . n 
C 3 258 ALA 258 240 240 ALA ALA C . n 
C 3 259 PHE 259 241 241 PHE PHE C . n 
C 3 260 ALA 260 242 242 ALA ALA C . n 
C 3 261 THR 261 243 243 THR THR C . n 
C 3 262 GLY 262 244 244 GLY GLY C . n 
C 3 263 SER 263 245 245 SER SER C . n 
C 3 264 ASP 264 246 246 ASP ASP C . n 
C 3 265 ASP 265 247 247 ASP ASP C . n 
C 3 266 ALA 266 248 248 ALA ALA C . n 
C 3 267 THR 267 249 249 THR THR C . n 
C 3 268 CYS 268 250 250 CYS CYS C . n 
C 3 269 ARG 269 251 251 ARG ARG C . n 
C 3 270 LEU 270 252 252 LEU LEU C . n 
C 3 271 PHE 271 253 253 PHE PHE C . n 
C 3 272 ASP 272 254 254 ASP ASP C . n 
C 3 273 LEU 273 255 255 LEU LEU C . n 
C 3 274 ARG 274 256 256 ARG ARG C . n 
C 3 275 ALA 275 257 257 ALA ALA C . n 
C 3 276 ASP 276 258 258 ASP ASP C . n 
C 3 277 GLN 277 259 259 GLN GLN C . n 
C 3 278 GLU 278 260 260 GLU GLU C . n 
C 3 279 LEU 279 261 261 LEU LEU C . n 
C 3 280 MET 280 262 262 MET MET C . n 
C 3 281 THR 281 263 263 THR THR C . n 
C 3 282 TYR 282 264 264 TYR TYR C . n 
C 3 283 SER 283 265 265 SER SER C . n 
C 3 284 HIS 284 266 266 HIS HIS C . n 
C 3 285 ASP 285 267 267 ASP ASP C . n 
C 3 286 ASN 286 268 268 ASN ASN C . n 
C 3 287 ILE 287 269 269 ILE ILE C . n 
C 3 288 ILE 288 270 270 ILE ILE C . n 
C 3 289 CYS 289 271 271 CYS CYS C . n 
C 3 290 GLY 290 272 272 GLY GLY C . n 
C 3 291 ILE 291 273 273 ILE ILE C . n 
C 3 292 THR 292 274 274 THR THR C . n 
C 3 293 SER 293 275 275 SER SER C . n 
C 3 294 VAL 294 276 276 VAL VAL C . n 
C 3 295 SER 295 277 277 SER SER C . n 
C 3 296 PHE 296 278 278 PHE PHE C . n 
C 3 297 SER 297 279 279 SER SER C . n 
C 3 298 LYS 298 280 280 LYS LYS C . n 
C 3 299 SER 299 281 281 SER SER C . n 
C 3 300 GLY 300 282 282 GLY GLY C . n 
C 3 301 ARG 301 283 283 ARG ARG C . n 
C 3 302 LEU 302 284 284 LEU LEU C . n 
C 3 303 LEU 303 285 285 LEU LEU C . n 
C 3 304 LEU 304 286 286 LEU LEU C . n 
C 3 305 ALA 305 287 287 ALA ALA C . n 
C 3 306 GLY 306 288 288 GLY GLY C . n 
C 3 307 TYR 307 289 289 TYR TYR C . n 
C 3 308 ASP 308 290 290 ASP ASP C . n 
C 3 309 ASP 309 291 291 ASP ASP C . n 
C 3 310 PHE 310 292 292 PHE PHE C . n 
C 3 311 ASN 311 293 293 ASN ASN C . n 
C 3 312 CYS 312 294 294 CYS CYS C . n 
C 3 313 ASN 313 295 295 ASN ASN C . n 
C 3 314 VAL 314 296 296 VAL VAL C . n 
C 3 315 TRP 315 297 297 TRP TRP C . n 
C 3 316 ASP 316 298 298 ASP ASP C . n 
C 3 317 ALA 317 299 299 ALA ALA C . n 
C 3 318 LEU 318 300 300 LEU LEU C . n 
C 3 319 LYS 319 301 301 LYS LYS C . n 
C 3 320 ALA 320 302 302 ALA ALA C . n 
C 3 321 ASP 321 303 303 ASP ASP C . n 
C 3 322 ARG 322 304 304 ARG ARG C . n 
C 3 323 ALA 323 305 305 ALA ALA C . n 
C 3 324 GLY 324 306 306 GLY GLY C . n 
C 3 325 VAL 325 307 307 VAL VAL C . n 
C 3 326 LEU 326 308 308 LEU LEU C . n 
C 3 327 ALA 327 309 309 ALA ALA C . n 
C 3 328 GLY 328 310 310 GLY GLY C . n 
C 3 329 HIS 329 311 311 HIS HIS C . n 
C 3 330 ASP 330 312 312 ASP ASP C . n 
C 3 331 ASN 331 313 313 ASN ASN C . n 
C 3 332 ARG 332 314 314 ARG ARG C . n 
C 3 333 VAL 333 315 315 VAL VAL C . n 
C 3 334 SER 334 316 316 SER SER C . n 
C 3 335 CYS 335 317 317 CYS CYS C . n 
C 3 336 LEU 336 318 318 LEU LEU C . n 
C 3 337 GLY 337 319 319 GLY GLY C . n 
C 3 338 VAL 338 320 320 VAL VAL C . n 
C 3 339 THR 339 321 321 THR THR C . n 
C 3 340 ASP 340 322 322 ASP ASP C . n 
C 3 341 ASP 341 323 323 ASP ASP C . n 
C 3 342 GLY 342 324 324 GLY GLY C . n 
C 3 343 MET 343 325 325 MET MET C . n 
C 3 344 ALA 344 326 326 ALA ALA C . n 
C 3 345 VAL 345 327 327 VAL VAL C . n 
C 3 346 ALA 346 328 328 ALA ALA C . n 
C 3 347 THR 347 329 329 THR THR C . n 
C 3 348 GLY 348 330 330 GLY GLY C . n 
C 3 349 SER 349 331 331 SER SER C . n 
C 3 350 TRP 350 332 332 TRP TRP C . n 
C 3 351 ASP 351 333 333 ASP ASP C . n 
C 3 352 SER 352 334 334 SER SER C . n 
C 3 353 PHE 353 335 335 PHE PHE C . n 
C 3 354 LEU 354 336 336 LEU LEU C . n 
C 3 355 LYS 355 337 337 LYS LYS C . n 
C 3 356 ILE 356 338 338 ILE ILE C . n 
C 3 357 TRP 357 339 339 TRP TRP C . n 
C 3 358 ASN 358 340 340 ASN ASN C . n 
D 4 1   MET 1   1   ?   ?   ?   D . n 
D 4 2   ALA 2   2   ?   ?   ?   D . n 
D 4 3   SER 3   3   ?   ?   ?   D . n 
D 4 4   ASN 4   4   ?   ?   ?   D . n 
D 4 5   ASN 5   5   ?   ?   ?   D . n 
D 4 6   THR 6   6   ?   ?   ?   D . n 
D 4 7   ALA 7   7   ?   ?   ?   D . n 
D 4 8   SER 8   8   ?   ?   ?   D . n 
D 4 9   ILE 9   9   ?   ?   ?   D . n 
D 4 10  ALA 10  10  ?   ?   ?   D . n 
D 4 11  GLN 11  11  ?   ?   ?   D . n 
D 4 12  ALA 12  12  12  ALA ALA D . n 
D 4 13  ARG 13  13  13  ARG ARG D . n 
D 4 14  LYS 14  14  14  LYS LYS D . n 
D 4 15  LEU 15  15  15  LEU LEU D . n 
D 4 16  VAL 16  16  16  VAL VAL D . n 
D 4 17  GLU 17  17  17  GLU GLU D . n 
D 4 18  GLN 18  18  18  GLN GLN D . n 
D 4 19  LEU 19  19  19  LEU LEU D . n 
D 4 20  LYS 20  20  20  LYS LYS D . n 
D 4 21  MET 21  21  21  MET MET D . n 
D 4 22  GLU 22  22  22  GLU GLU D . n 
D 4 23  ALA 23  23  23  ALA ALA D . n 
D 4 24  ASN 24  24  24  ASN ASN D . n 
D 4 25  ILE 25  25  25  ILE ILE D . n 
D 4 26  ASP 26  26  26  ASP ASP D . n 
D 4 27  ARG 27  27  27  ARG ARG D . n 
D 4 28  ILE 28  28  28  ILE ILE D . n 
D 4 29  LYS 29  29  29  LYS LYS D . n 
D 4 30  VAL 30  30  30  VAL VAL D . n 
D 4 31  SER 31  31  31  SER SER D . n 
D 4 32  LYS 32  32  32  LYS LYS D . n 
D 4 33  ALA 33  33  33  ALA ALA D . n 
D 4 34  ALA 34  34  34  ALA ALA D . n 
D 4 35  ALA 35  35  35  ALA ALA D . n 
D 4 36  ASP 36  36  36  ASP ASP D . n 
D 4 37  LEU 37  37  37  LEU LEU D . n 
D 4 38  MET 38  38  38  MET MET D . n 
D 4 39  ALA 39  39  39  ALA ALA D . n 
D 4 40  TYR 40  40  40  TYR TYR D . n 
D 4 41  CYS 41  41  41  CYS CYS D . n 
D 4 42  GLU 42  42  42  GLU GLU D . n 
D 4 43  ALA 43  43  43  ALA ALA D . n 
D 4 44  HIS 44  44  44  HIS HIS D . n 
D 4 45  ALA 45  45  45  ALA ALA D . n 
D 4 46  LYS 46  46  46  LYS LYS D . n 
D 4 47  GLU 47  47  47  GLU GLU D . n 
D 4 48  ASP 48  48  48  ASP ASP D . n 
D 4 49  PRO 49  49  49  PRO PRO D . n 
D 4 50  LEU 50  50  50  LEU LEU D . n 
D 4 51  LEU 51  51  51  LEU LEU D . n 
D 4 52  THR 52  52  52  THR THR D . n 
D 4 53  PRO 53  53  53  PRO PRO D . n 
D 4 54  VAL 54  54  54  VAL VAL D . n 
D 4 55  PRO 55  55  55  PRO PRO D . n 
D 4 56  ALA 56  56  56  ALA ALA D . n 
D 4 57  SER 57  57  57  SER SER D . n 
D 4 58  GLU 58  58  58  GLU GLU D . n 
D 4 59  ASN 59  59  59  ASN ASN D . n 
D 4 60  PRO 60  60  60  PRO PRO D . n 
D 4 61  PHE 61  61  61  PHE PHE D . n 
D 4 62  ARG 62  62  ?   ?   ?   D . n 
D 4 63  GLU 63  63  ?   ?   ?   D . n 
D 4 64  LYS 64  64  ?   ?   ?   D . n 
D 4 65  LYS 65  65  ?   ?   ?   D . n 
D 4 66  PHE 66  66  ?   ?   ?   D . n 
D 4 67  PHE 67  67  ?   ?   ?   D . n 
D 4 68  CYS 68  68  ?   ?   ?   D . n 
D 4 69  ALA 69  69  ?   ?   ?   D . n 
D 4 70  ILE 70  70  ?   ?   ?   D . n 
D 4 71  LEU 71  71  ?   ?   ?   D . n 
E 5 1   ASP 1   1   ?   ?   ?   E . n 
E 5 2   VAL 2   2   2   VAL VAL E . n 
E 5 3   GLN 3   3   3   GLN GLN E . n 
E 5 4   LEU 4   4   4   LEU LEU E . n 
E 5 5   VAL 5   5   5   VAL VAL E . n 
E 5 6   GLU 6   6   6   GLU GLU E . n 
E 5 7   SER 7   7   7   SER SER E . n 
E 5 8   GLY 8   8   8   GLY GLY E . n 
E 5 9   GLY 9   9   9   GLY GLY E . n 
E 5 10  GLY 10  10  10  GLY GLY E . n 
E 5 11  LEU 11  11  11  LEU LEU E . n 
E 5 12  VAL 12  12  12  VAL VAL E . n 
E 5 13  GLN 13  13  13  GLN GLN E . n 
E 5 14  PRO 14  14  14  PRO PRO E . n 
E 5 15  GLY 15  15  15  GLY GLY E . n 
E 5 16  GLY 16  16  16  GLY GLY E . n 
E 5 17  SER 17  17  17  SER SER E . n 
E 5 18  ARG 18  18  18  ARG ARG E . n 
E 5 19  LYS 19  19  19  LYS LYS E . n 
E 5 20  LEU 20  20  20  LEU LEU E . n 
E 5 21  SER 21  21  21  SER SER E . n 
E 5 22  CYS 22  22  22  CYS CYS E . n 
E 5 23  SER 23  23  23  SER SER E . n 
E 5 24  ALA 24  24  24  ALA ALA E . n 
E 5 25  SER 25  25  25  SER SER E . n 
E 5 26  GLY 26  26  26  GLY GLY E . n 
E 5 27  PHE 27  27  27  PHE PHE E . n 
E 5 28  ALA 28  28  28  ALA ALA E . n 
E 5 29  PHE 29  29  29  PHE PHE E . n 
E 5 30  SER 30  30  30  SER SER E . n 
E 5 31  SER 31  31  31  SER SER E . n 
E 5 32  PHE 32  32  32  PHE PHE E . n 
E 5 33  GLY 33  33  33  GLY GLY E . n 
E 5 34  MET 34  34  34  MET MET E . n 
E 5 35  HIS 35  35  35  HIS HIS E . n 
E 5 36  TRP 36  36  ?   ?   ?   E . n 
E 5 37  VAL 37  37  37  VAL VAL E . n 
E 5 38  ARG 38  38  38  ARG ARG E . n 
E 5 39  GLN 39  39  39  GLN GLN E . n 
E 5 40  ALA 40  40  40  ALA ALA E . n 
E 5 41  PRO 41  41  41  PRO PRO E . n 
E 5 42  GLU 42  42  42  GLU GLU E . n 
E 5 43  LYS 43  43  43  LYS LYS E . n 
E 5 44  GLY 44  44  44  GLY GLY E . n 
E 5 45  LEU 45  45  45  LEU LEU E . n 
E 5 46  GLU 46  46  46  GLU GLU E . n 
E 5 47  TRP 47  47  47  TRP TRP E . n 
E 5 48  VAL 48  48  48  VAL VAL E . n 
E 5 49  ALA 49  49  49  ALA ALA E . n 
E 5 50  TYR 50  50  50  TYR TYR E . n 
E 5 51  ILE 51  51  51  ILE ILE E . n 
E 5 52  SER 52  52  52  SER SER E . n 
E 5 53  SER 53  53  53  SER SER E . n 
E 5 54  GLY 54  54  54  GLY GLY E . n 
E 5 55  SER 55  55  55  SER SER E . n 
E 5 56  GLY 56  56  56  GLY GLY E . n 
E 5 57  THR 57  57  57  THR THR E . n 
E 5 58  ILE 58  58  58  ILE ILE E . n 
E 5 59  TYR 59  59  59  TYR TYR E . n 
E 5 60  TYR 60  60  60  TYR TYR E . n 
E 5 61  ALA 61  61  61  ALA ALA E . n 
E 5 62  ASP 62  62  62  ASP ASP E . n 
E 5 63  THR 63  63  63  THR THR E . n 
E 5 64  VAL 64  64  64  VAL VAL E . n 
E 5 65  LYS 65  65  65  LYS LYS E . n 
E 5 66  GLY 66  66  66  GLY GLY E . n 
E 5 67  ARG 67  67  67  ARG ARG E . n 
E 5 68  PHE 68  68  68  PHE PHE E . n 
E 5 69  THR 69  69  69  THR THR E . n 
E 5 70  ILE 70  70  70  ILE ILE E . n 
E 5 71  SER 71  71  71  SER SER E . n 
E 5 72  ARG 72  72  72  ARG ARG E . n 
E 5 73  ASP 73  73  73  ASP ASP E . n 
E 5 74  ASP 74  74  74  ASP ASP E . n 
E 5 75  PRO 75  75  75  PRO PRO E . n 
E 5 76  LYS 76  76  76  LYS LYS E . n 
E 5 77  ASN 77  77  77  ASN ASN E . n 
E 5 78  THR 78  78  78  THR THR E . n 
E 5 79  LEU 79  79  79  LEU LEU E . n 
E 5 80  PHE 80  80  80  PHE PHE E . n 
E 5 81  LEU 81  81  81  LEU LEU E . n 
E 5 82  GLN 82  82  82  GLN GLN E . n 
E 5 83  MET 83  83  83  MET MET E . n 
E 5 84  THR 84  84  84  THR THR E . n 
E 5 85  SER 85  85  85  SER SER E . n 
E 5 86  LEU 86  86  86  LEU LEU E . n 
E 5 87  ARG 87  87  87  ARG ARG E . n 
E 5 88  SER 88  88  88  SER SER E . n 
E 5 89  GLU 89  89  89  GLU GLU E . n 
E 5 90  ASP 90  90  90  ASP ASP E . n 
E 5 91  THR 91  91  91  THR THR E . n 
E 5 92  ALA 92  92  92  ALA ALA E . n 
E 5 93  MET 93  93  93  MET MET E . n 
E 5 94  TYR 94  94  94  TYR TYR E . n 
E 5 95  TYR 95  95  95  TYR TYR E . n 
E 5 96  CYS 96  96  96  CYS CYS E . n 
E 5 97  VAL 97  97  97  VAL VAL E . n 
E 5 98  ARG 98  98  98  ARG ARG E . n 
E 5 99  SER 99  99  99  SER SER E . n 
E 5 100 ILE 100 100 100 ILE ILE E . n 
E 5 101 TYR 101 101 101 TYR TYR E . n 
E 5 102 TYR 102 102 102 TYR TYR E . n 
E 5 103 TYR 103 103 103 TYR TYR E . n 
E 5 104 GLY 104 104 104 GLY GLY E . n 
E 5 105 SER 105 105 105 SER SER E . n 
E 5 106 SER 106 106 106 SER SER E . n 
E 5 107 PRO 107 107 107 PRO PRO E . n 
E 5 108 PHE 108 108 108 PHE PHE E . n 
E 5 109 ASP 109 109 109 ASP ASP E . n 
E 5 110 PHE 110 110 110 PHE PHE E . n 
E 5 111 TRP 111 111 111 TRP TRP E . n 
E 5 112 GLY 112 112 112 GLY GLY E . n 
E 5 113 GLN 113 113 113 GLN GLN E . n 
E 5 114 GLY 114 114 114 GLY GLY E . n 
E 5 115 THR 115 115 115 THR THR E . n 
E 5 116 THR 116 116 116 THR THR E . n 
E 5 117 LEU 117 117 117 LEU LEU E . n 
E 5 118 THR 118 118 118 THR THR E . n 
E 5 119 VAL 119 119 119 VAL VAL E . n 
E 5 120 SER 120 119 ?   ?   ?   E A n 
E 5 121 SER 121 119 ?   ?   ?   E B n 
E 5 122 GLY 122 119 ?   ?   ?   E C n 
E 5 123 GLY 123 119 ?   ?   ?   E D n 
E 5 124 GLY 124 119 ?   ?   ?   E E n 
E 5 125 GLY 125 119 ?   ?   ?   E F n 
E 5 126 SER 126 119 ?   ?   ?   E G n 
E 5 127 GLY 127 119 ?   ?   ?   E H n 
E 5 128 GLY 128 119 ?   ?   ?   E I n 
E 5 129 GLY 129 119 ?   ?   ?   E J n 
E 5 130 GLY 130 119 ?   ?   ?   E K n 
E 5 131 SER 131 119 ?   ?   ?   E L n 
E 5 132 GLY 132 119 ?   ?   ?   E M n 
E 5 133 GLY 133 119 ?   ?   ?   E N n 
E 5 134 GLY 134 119 ?   ?   ?   E O n 
E 5 135 GLY 135 119 ?   ?   ?   E P n 
E 5 136 SER 136 119 ?   ?   ?   E Q n 
E 5 137 ASP 137 125 125 ASP ASP E . n 
E 5 138 ILE 138 126 126 ILE ILE E . n 
E 5 139 VAL 139 127 127 VAL VAL E . n 
E 5 140 MET 140 128 128 MET MET E . n 
E 5 141 THR 141 129 129 THR THR E . n 
E 5 142 GLN 142 130 130 GLN GLN E . n 
E 5 143 ALA 143 131 131 ALA ALA E . n 
E 5 144 THR 144 132 132 THR THR E . n 
E 5 145 SER 145 133 133 SER SER E . n 
E 5 146 SER 146 134 134 SER SER E . n 
E 5 147 VAL 147 135 135 VAL VAL E . n 
E 5 148 PRO 148 136 136 PRO PRO E . n 
E 5 149 VAL 149 137 137 VAL VAL E . n 
E 5 150 THR 150 138 138 THR THR E . n 
E 5 151 PRO 151 139 139 PRO PRO E . n 
E 5 152 GLY 152 140 140 GLY GLY E . n 
E 5 153 GLU 153 141 141 GLU GLU E . n 
E 5 154 SER 154 142 142 SER SER E . n 
E 5 155 VAL 155 143 143 VAL VAL E . n 
E 5 156 SER 156 144 144 SER SER E . n 
E 5 157 ILE 157 145 145 ILE ILE E . n 
E 5 158 SER 158 146 146 SER SER E . n 
E 5 159 CYS 159 147 147 CYS CYS E . n 
E 5 160 ARG 160 148 148 ARG ARG E . n 
E 5 161 SER 161 149 149 SER SER E . n 
E 5 162 SER 162 150 150 SER SER E . n 
E 5 163 LYS 163 151 151 LYS LYS E . n 
E 5 164 SER 164 152 152 SER SER E . n 
E 5 165 LEU 165 153 153 LEU LEU E . n 
E 5 166 LEU 166 154 154 LEU LEU E . n 
E 5 167 HIS 167 155 155 HIS HIS E . n 
E 5 168 SER 168 156 156 SER SER E . n 
E 5 169 ASN 169 157 157 ASN ASN E . n 
E 5 170 GLY 170 158 158 GLY GLY E . n 
E 5 171 ASN 171 159 159 ASN ASN E . n 
E 5 172 THR 172 160 160 THR THR E . n 
E 5 173 TYR 173 161 161 TYR TYR E . n 
E 5 174 LEU 174 162 162 LEU LEU E . n 
E 5 175 TYR 175 163 163 TYR TYR E . n 
E 5 176 TRP 176 164 164 TRP TRP E . n 
E 5 177 PHE 177 165 165 PHE PHE E . n 
E 5 178 LEU 178 166 166 LEU LEU E . n 
E 5 179 GLN 179 167 167 GLN GLN E . n 
E 5 180 ARG 180 168 168 ARG ARG E . n 
E 5 181 PRO 181 169 169 PRO PRO E . n 
E 5 182 GLY 182 170 170 GLY GLY E . n 
E 5 183 GLN 183 171 171 GLN GLN E . n 
E 5 184 SER 184 172 172 SER SER E . n 
E 5 185 PRO 185 173 173 PRO PRO E . n 
E 5 186 GLN 186 174 174 GLN GLN E . n 
E 5 187 LEU 187 175 175 LEU LEU E . n 
E 5 188 LEU 188 176 176 LEU LEU E . n 
E 5 189 ILE 189 177 177 ILE ILE E . n 
E 5 190 TYR 190 178 178 TYR TYR E . n 
E 5 191 ARG 191 179 179 ARG ARG E . n 
E 5 192 MET 192 180 180 MET MET E . n 
E 5 193 SER 193 181 181 SER SER E . n 
E 5 194 ASN 194 182 182 ASN ASN E . n 
E 5 195 LEU 195 183 183 LEU LEU E . n 
E 5 196 ALA 196 184 184 ALA ALA E . n 
E 5 197 SER 197 185 185 SER SER E . n 
E 5 198 GLY 198 186 186 GLY GLY E . n 
E 5 199 VAL 199 187 187 VAL VAL E . n 
E 5 200 PRO 200 188 188 PRO PRO E . n 
E 5 201 ASP 201 189 189 ASP ASP E . n 
E 5 202 ARG 202 190 190 ARG ARG E . n 
E 5 203 PHE 203 191 191 PHE PHE E . n 
E 5 204 SER 204 192 192 SER SER E . n 
E 5 205 GLY 205 193 193 GLY GLY E . n 
E 5 206 SER 206 194 194 SER SER E . n 
E 5 207 GLY 207 195 195 GLY GLY E . n 
E 5 208 SER 208 196 196 SER SER E . n 
E 5 209 GLY 209 197 197 GLY GLY E . n 
E 5 210 THR 210 198 198 THR THR E . n 
E 5 211 ALA 211 199 199 ALA ALA E . n 
E 5 212 PHE 212 200 200 PHE PHE E . n 
E 5 213 THR 213 201 201 THR THR E . n 
E 5 214 LEU 214 202 202 LEU LEU E . n 
E 5 215 THR 215 203 203 THR THR E . n 
E 5 216 ILE 216 204 204 ILE ILE E . n 
E 5 217 SER 217 205 205 SER SER E . n 
E 5 218 ARG 218 206 206 ARG ARG E . n 
E 5 219 LEU 219 207 207 LEU LEU E . n 
E 5 220 GLU 220 208 208 GLU GLU E . n 
E 5 221 ALA 221 209 209 ALA ALA E . n 
E 5 222 GLU 222 210 210 GLU GLU E . n 
E 5 223 ASP 223 211 211 ASP ASP E . n 
E 5 224 VAL 224 212 212 VAL VAL E . n 
E 5 225 GLY 225 213 213 GLY GLY E . n 
E 5 226 VAL 226 214 214 VAL VAL E . n 
E 5 227 TYR 227 215 215 TYR TYR E . n 
E 5 228 TYR 228 216 216 TYR TYR E . n 
E 5 229 CYS 229 217 217 CYS CYS E . n 
E 5 230 MET 230 218 218 MET MET E . n 
E 5 231 GLN 231 219 219 GLN GLN E . n 
E 5 232 HIS 232 220 220 HIS HIS E . n 
E 5 233 LEU 233 221 221 LEU LEU E . n 
E 5 234 GLU 234 222 222 GLU GLU E . n 
E 5 235 TYR 235 223 223 TYR TYR E . n 
E 5 236 PRO 236 224 224 PRO PRO E . n 
E 5 237 LEU 237 225 225 LEU LEU E . n 
E 5 238 THR 238 226 226 THR THR E . n 
E 5 239 PHE 239 227 227 PHE PHE E . n 
E 5 240 GLY 240 228 228 GLY GLY E . n 
E 5 241 ALA 241 229 229 ALA ALA E . n 
E 5 242 GLY 242 230 230 GLY GLY E . n 
E 5 243 THR 243 231 231 THR THR E . n 
E 5 244 LYS 244 232 232 LYS LYS E . n 
E 5 245 LEU 245 233 233 LEU LEU E . n 
E 5 246 GLU 246 234 234 GLU GLU E . n 
E 5 247 LEU 247 235 235 LEU LEU E . n 
E 5 248 LYS 248 236 ?   ?   ?   E . n 
E 5 249 ALA 249 237 ?   ?   ?   E . n 
E 5 250 ALA 250 238 ?   ?   ?   E . n 
E 5 251 ALA 251 239 ?   ?   ?   E . n 
E 5 252 LEU 252 240 ?   ?   ?   E . n 
E 5 253 GLU 253 241 ?   ?   ?   E . n 
E 5 254 VAL 254 242 ?   ?   ?   E . n 
E 5 255 LEU 255 243 ?   ?   ?   E . n 
E 5 256 PHE 256 244 ?   ?   ?   E . n 
E 5 257 GLN 257 245 ?   ?   ?   E . n 
E 5 258 GLY 258 246 ?   ?   ?   E . n 
E 5 259 PRO 259 247 ?   ?   ?   E . n 
E 5 260 HIS 260 248 ?   ?   ?   E . n 
E 5 261 HIS 261 249 ?   ?   ?   E . n 
E 5 262 HIS 262 250 ?   ?   ?   E . n 
E 5 263 HIS 263 251 ?   ?   ?   E . n 
E 5 264 HIS 264 252 ?   ?   ?   E . n 
E 5 265 HIS 265 253 ?   ?   ?   E . n 
E 5 266 HIS 266 254 ?   ?   ?   E . n 
E 5 267 HIS 267 255 ?   ?   ?   E . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        7LD 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   7LD 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
_pdbx_nonpoly_scheme.asym_id         F 
_pdbx_nonpoly_scheme.entity_id       6 
_pdbx_nonpoly_scheme.mon_id          7LD 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     501 
_pdbx_nonpoly_scheme.auth_seq_num    401 
_pdbx_nonpoly_scheme.pdb_mon_id      7LD 
_pdbx_nonpoly_scheme.auth_mon_id     7LD 
_pdbx_nonpoly_scheme.pdb_strand_id   A 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 A ARG 140 ? CG  ? A ARG 140 CG  
2   1 Y 1 A ARG 140 ? CD  ? A ARG 140 CD  
3   1 Y 1 A ARG 140 ? NE  ? A ARG 140 NE  
4   1 Y 1 A ARG 140 ? CZ  ? A ARG 140 CZ  
5   1 Y 1 A ARG 140 ? NH1 ? A ARG 140 NH1 
6   1 Y 1 A ARG 140 ? NH2 ? A ARG 140 NH2 
7   1 Y 1 A ARG 185 ? CG  ? A ARG 185 CG  
8   1 Y 1 A ARG 185 ? CD  ? A ARG 185 CD  
9   1 Y 1 A ARG 185 ? NE  ? A ARG 185 NE  
10  1 Y 1 A ARG 185 ? CZ  ? A ARG 185 CZ  
11  1 Y 1 A ARG 185 ? NH1 ? A ARG 185 NH1 
12  1 Y 1 A ARG 185 ? NH2 ? A ARG 185 NH2 
13  1 Y 1 A ASN 187 ? CG  ? A ASN 187 CG  
14  1 Y 1 A ASN 187 ? OD1 ? A ASN 187 OD1 
15  1 Y 1 A ASN 187 ? ND2 ? A ASN 187 ND2 
16  1 Y 1 A ARG 189 ? CG  ? A ARG 189 CG  
17  1 Y 1 A ARG 189 ? CD  ? A ARG 189 CD  
18  1 Y 1 A ARG 189 ? NE  ? A ARG 189 NE  
19  1 Y 1 A ARG 189 ? CZ  ? A ARG 189 CZ  
20  1 Y 1 A ARG 189 ? NH1 ? A ARG 189 NH1 
21  1 Y 1 A ARG 189 ? NH2 ? A ARG 189 NH2 
22  1 Y 1 A PHE 213 ? CG  ? A PHE 213 CG  
23  1 Y 1 A PHE 213 ? CD1 ? A PHE 213 CD1 
24  1 Y 1 A PHE 213 ? CD2 ? A PHE 213 CD2 
25  1 Y 1 A PHE 213 ? CE1 ? A PHE 213 CE1 
26  1 Y 1 A PHE 213 ? CE2 ? A PHE 213 CE2 
27  1 Y 1 A PHE 213 ? CZ  ? A PHE 213 CZ  
28  1 Y 1 A ASP 218 ? CG  ? A ASP 218 CG  
29  1 Y 1 A ASP 218 ? OD1 ? A ASP 218 OD1 
30  1 Y 1 A ASP 218 ? OD2 ? A ASP 218 OD2 
31  1 Y 1 A SER 219 ? OG  ? A SER 219 OG  
32  1 Y 1 A LYS 220 ? CG  ? A LYS 220 CG  
33  1 Y 1 A LYS 220 ? CD  ? A LYS 220 CD  
34  1 Y 1 A LYS 220 ? CE  ? A LYS 220 CE  
35  1 Y 1 A LYS 220 ? NZ  ? A LYS 220 NZ  
36  1 Y 1 A PHE 222 ? CG  ? A PHE 222 CG  
37  1 Y 1 A PHE 222 ? CD1 ? A PHE 222 CD1 
38  1 Y 1 A PHE 222 ? CD2 ? A PHE 222 CD2 
39  1 Y 1 A PHE 222 ? CE1 ? A PHE 222 CE1 
40  1 Y 1 A PHE 222 ? CE2 ? A PHE 222 CE2 
41  1 Y 1 A PHE 222 ? CZ  ? A PHE 222 CZ  
42  1 Y 1 A LYS 223 ? CG  ? A LYS 223 CG  
43  1 Y 1 A LYS 223 ? CD  ? A LYS 223 CD  
44  1 Y 1 A LYS 223 ? CE  ? A LYS 223 CE  
45  1 Y 1 A LYS 223 ? NZ  ? A LYS 223 NZ  
46  1 Y 1 A ASP 231 ? CG  ? A ASP 231 CG  
47  1 Y 1 A ASP 231 ? OD1 ? A ASP 231 OD1 
48  1 Y 1 A ASP 231 ? OD2 ? A ASP 231 OD2 
49  1 Y 1 A ASP 232 ? CG  ? A ASP 232 CG  
50  1 Y 1 A ASP 232 ? OD1 ? A ASP 232 OD1 
51  1 Y 1 A ASP 232 ? OD2 ? A ASP 232 OD2 
52  1 Y 1 A ILE 315 ? CG1 ? A ILE 315 CG1 
53  1 Y 1 A ILE 315 ? CG2 ? A ILE 315 CG2 
54  1 Y 1 A ILE 315 ? CD1 ? A ILE 315 CD1 
55  1 Y 1 A GLN 319 ? CG  ? A GLN 319 CG  
56  1 Y 1 A GLN 319 ? CD  ? A GLN 319 CD  
57  1 Y 1 A GLN 319 ? OE1 ? A GLN 319 OE1 
58  1 Y 1 A GLN 319 ? NE2 ? A GLN 319 NE2 
59  1 Y 1 A ASN 354 ? CG  ? A ASN 354 CG  
60  1 Y 1 A ASN 354 ? OD1 ? A ASN 354 OD1 
61  1 Y 1 A ASN 354 ? ND2 ? A ASN 354 ND2 
62  1 Y 1 A GLU 355 ? CG  ? A GLU 355 CG  
63  1 Y 1 A GLU 355 ? CD  ? A GLU 355 CD  
64  1 Y 1 A GLU 355 ? OE1 ? A GLU 355 OE1 
65  1 Y 1 A GLU 355 ? OE2 ? A GLU 355 OE2 
66  1 Y 1 A ASP 356 ? CG  ? A ASP 356 CG  
67  1 Y 1 A ASP 356 ? OD1 ? A ASP 356 OD1 
68  1 Y 1 A ASP 356 ? OD2 ? A ASP 356 OD2 
69  1 Y 1 A SER 392 ? OG  ? A SER 392 OG  
70  1 Y 1 A ARG 393 ? CG  ? A ARG 393 CG  
71  1 Y 1 A ARG 393 ? CD  ? A ARG 393 CD  
72  1 Y 1 A ARG 393 ? NE  ? A ARG 393 NE  
73  1 Y 1 A ARG 393 ? CZ  ? A ARG 393 CZ  
74  1 Y 1 A ARG 393 ? NH1 ? A ARG 393 NH1 
75  1 Y 1 A ARG 393 ? NH2 ? A ARG 393 NH2 
76  1 Y 1 B GLU 28  ? CG  ? B GLU 28  CG  
77  1 Y 1 B GLU 28  ? CD  ? B GLU 28  CD  
78  1 Y 1 B GLU 28  ? OE1 ? B GLU 28  OE1 
79  1 Y 1 B GLU 28  ? OE2 ? B GLU 28  OE2 
80  1 Y 1 B ARG 32  ? CG  ? B ARG 32  CG  
81  1 Y 1 B ARG 32  ? CD  ? B ARG 32  CD  
82  1 Y 1 B ARG 32  ? NE  ? B ARG 32  NE  
83  1 Y 1 B ARG 32  ? CZ  ? B ARG 32  CZ  
84  1 Y 1 B ARG 32  ? NH1 ? B ARG 32  NH1 
85  1 Y 1 B ARG 32  ? NH2 ? B ARG 32  NH2 
86  1 Y 1 B GLN 52  ? CG  ? B GLN 52  CG  
87  1 Y 1 B GLN 52  ? CD  ? B GLN 52  CD  
88  1 Y 1 B GLN 52  ? OE1 ? B GLN 52  OE1 
89  1 Y 1 B GLN 52  ? NE2 ? B GLN 52  NE2 
90  1 Y 1 B PHE 70  ? CG  ? B PHE 70  CG  
91  1 Y 1 B PHE 70  ? CD1 ? B PHE 70  CD1 
92  1 Y 1 B PHE 70  ? CD2 ? B PHE 70  CD2 
93  1 Y 1 B PHE 70  ? CE1 ? B PHE 70  CE1 
94  1 Y 1 B PHE 70  ? CE2 ? B PHE 70  CE2 
95  1 Y 1 B PHE 70  ? CZ  ? B PHE 70  CZ  
96  1 Y 1 B LYS 78  ? CG  ? B LYS 78  CG  
97  1 Y 1 B LYS 78  ? CD  ? B LYS 78  CD  
98  1 Y 1 B LYS 78  ? CE  ? B LYS 78  CE  
99  1 Y 1 B LYS 78  ? NZ  ? B LYS 78  NZ  
100 1 Y 1 B ARG 90  ? CG  ? B ARG 90  CG  
101 1 Y 1 B ARG 90  ? CD  ? B ARG 90  CD  
102 1 Y 1 B ARG 90  ? NE  ? B ARG 90  NE  
103 1 Y 1 B ARG 90  ? CZ  ? B ARG 90  CZ  
104 1 Y 1 B ARG 90  ? NH1 ? B ARG 90  NH1 
105 1 Y 1 B ARG 90  ? NH2 ? B ARG 90  NH2 
106 1 Y 1 B ASP 91  ? CG  ? B ASP 91  CG  
107 1 Y 1 B ASP 91  ? OD1 ? B ASP 91  OD1 
108 1 Y 1 B ASP 91  ? OD2 ? B ASP 91  OD2 
109 1 Y 1 B ARG 94  ? CG  ? B ARG 94  CG  
110 1 Y 1 B ARG 94  ? CD  ? B ARG 94  CD  
111 1 Y 1 B ARG 94  ? NE  ? B ARG 94  NE  
112 1 Y 1 B ARG 94  ? CZ  ? B ARG 94  CZ  
113 1 Y 1 B ARG 94  ? NH1 ? B ARG 94  NH1 
114 1 Y 1 B ARG 94  ? NH2 ? B ARG 94  NH2 
115 1 Y 1 B ASP 111 ? CG  ? B ASP 111 CG  
116 1 Y 1 B ASP 111 ? OD1 ? B ASP 111 OD1 
117 1 Y 1 B ASP 111 ? OD2 ? B ASP 111 OD2 
118 1 Y 1 B GLU 120 ? CG  ? B GLU 120 CG  
119 1 Y 1 B GLU 120 ? CD  ? B GLU 120 CD  
120 1 Y 1 B GLU 120 ? OE1 ? B GLU 120 OE1 
121 1 Y 1 B GLU 120 ? OE2 ? B GLU 120 OE2 
122 1 Y 1 B LEU 148 ? CG  ? B LEU 148 CG  
123 1 Y 1 B LEU 148 ? CD1 ? B LEU 148 CD1 
124 1 Y 1 B LEU 148 ? CD2 ? B LEU 148 CD2 
125 1 Y 1 B LYS 157 ? CG  ? B LYS 157 CG  
126 1 Y 1 B LYS 157 ? CD  ? B LYS 157 CD  
127 1 Y 1 B LYS 157 ? CE  ? B LYS 157 CE  
128 1 Y 1 B LYS 157 ? NZ  ? B LYS 157 NZ  
129 1 Y 1 B LYS 159 ? CG  ? B LYS 159 CG  
130 1 Y 1 B LYS 159 ? CD  ? B LYS 159 CD  
131 1 Y 1 B LYS 159 ? CE  ? B LYS 159 CE  
132 1 Y 1 B LYS 159 ? NZ  ? B LYS 159 NZ  
133 1 Y 1 B GLU 161 ? CG  ? B GLU 161 CG  
134 1 Y 1 B GLU 161 ? CD  ? B GLU 161 CD  
135 1 Y 1 B GLU 161 ? OE1 ? B GLU 161 OE1 
136 1 Y 1 B GLU 161 ? OE2 ? B GLU 161 OE2 
137 1 Y 1 B ASP 162 ? CG  ? B ASP 162 CG  
138 1 Y 1 B ASP 162 ? OD1 ? B ASP 162 OD1 
139 1 Y 1 B ASP 162 ? OD2 ? B ASP 162 OD2 
140 1 Y 1 B ARG 169 ? CG  ? B ARG 169 CG  
141 1 Y 1 B ARG 169 ? CD  ? B ARG 169 CD  
142 1 Y 1 B ARG 169 ? NE  ? B ARG 169 NE  
143 1 Y 1 B ARG 169 ? CZ  ? B ARG 169 CZ  
144 1 Y 1 B ARG 169 ? NH1 ? B ARG 169 NH1 
145 1 Y 1 B ARG 169 ? NH2 ? B ARG 169 NH2 
146 1 Y 1 B THR 171 ? OG1 ? B THR 171 OG1 
147 1 Y 1 B THR 171 ? CG2 ? B THR 171 CG2 
148 1 Y 1 B ARG 185 ? CG  ? B ARG 185 CG  
149 1 Y 1 B ARG 185 ? CD  ? B ARG 185 CD  
150 1 Y 1 B ARG 185 ? NE  ? B ARG 185 NE  
151 1 Y 1 B ARG 185 ? CZ  ? B ARG 185 CZ  
152 1 Y 1 B ARG 185 ? NH1 ? B ARG 185 NH1 
153 1 Y 1 B ARG 185 ? NH2 ? B ARG 185 NH2 
154 1 Y 1 B LYS 195 ? CG  ? B LYS 195 CG  
155 1 Y 1 B LYS 195 ? CD  ? B LYS 195 CD  
156 1 Y 1 B LYS 195 ? CE  ? B LYS 195 CE  
157 1 Y 1 B LYS 195 ? NZ  ? B LYS 195 NZ  
158 1 Y 1 B ASP 206 ? CG  ? B ASP 206 CG  
159 1 Y 1 B ASP 206 ? OD1 ? B ASP 206 OD1 
160 1 Y 1 B ASP 206 ? OD2 ? B ASP 206 OD2 
161 1 Y 1 B ARG 208 ? CG  ? B ARG 208 CG  
162 1 Y 1 B ARG 208 ? CD  ? B ARG 208 CD  
163 1 Y 1 B ARG 208 ? NE  ? B ARG 208 NE  
164 1 Y 1 B ARG 208 ? CZ  ? B ARG 208 CZ  
165 1 Y 1 B ARG 208 ? NH1 ? B ARG 208 NH1 
166 1 Y 1 B ARG 208 ? NH2 ? B ARG 208 NH2 
167 1 Y 1 C GLU 10  ? CG  ? C GLU 28  CG  
168 1 Y 1 C GLU 10  ? CD  ? C GLU 28  CD  
169 1 Y 1 C GLU 10  ? OE1 ? C GLU 28  OE1 
170 1 Y 1 C GLU 10  ? OE2 ? C GLU 28  OE2 
171 1 Y 1 C GLU 12  ? CG  ? C GLU 30  CG  
172 1 Y 1 C GLU 12  ? CD  ? C GLU 30  CD  
173 1 Y 1 C GLU 12  ? OE1 ? C GLU 30  OE1 
174 1 Y 1 C GLU 12  ? OE2 ? C GLU 30  OE2 
175 1 Y 1 C GLN 13  ? CG  ? C GLN 31  CG  
176 1 Y 1 C GLN 13  ? CD  ? C GLN 31  CD  
177 1 Y 1 C GLN 13  ? OE1 ? C GLN 31  OE1 
178 1 Y 1 C GLN 13  ? NE2 ? C GLN 31  NE2 
179 1 Y 1 C LYS 15  ? CG  ? C LYS 33  CG  
180 1 Y 1 C LYS 15  ? CD  ? C LYS 33  CD  
181 1 Y 1 C LYS 15  ? CE  ? C LYS 33  CE  
182 1 Y 1 C LYS 15  ? NZ  ? C LYS 33  NZ  
183 1 Y 1 C ASN 16  ? CG  ? C ASN 34  CG  
184 1 Y 1 C ASN 16  ? OD1 ? C ASN 34  OD1 
185 1 Y 1 C ASN 16  ? ND2 ? C ASN 34  ND2 
186 1 Y 1 C ARG 19  ? CG  ? C ARG 37  CG  
187 1 Y 1 C ARG 19  ? CD  ? C ARG 37  CD  
188 1 Y 1 C ARG 19  ? NE  ? C ARG 37  NE  
189 1 Y 1 C ARG 19  ? CZ  ? C ARG 37  CZ  
190 1 Y 1 C ARG 19  ? NH1 ? C ARG 37  NH1 
191 1 Y 1 C ARG 19  ? NH2 ? C ARG 37  NH2 
192 1 Y 1 C ASP 20  ? CG  ? C ASP 38  CG  
193 1 Y 1 C ASP 20  ? OD1 ? C ASP 38  OD1 
194 1 Y 1 C ASP 20  ? OD2 ? C ASP 38  OD2 
195 1 Y 1 C LYS 23  ? CG  ? C LYS 41  CG  
196 1 Y 1 C LYS 23  ? CD  ? C LYS 41  CD  
197 1 Y 1 C LYS 23  ? CE  ? C LYS 41  CE  
198 1 Y 1 C LYS 23  ? NZ  ? C LYS 41  NZ  
199 1 Y 1 C ASN 35  ? CG  ? C ASN 53  CG  
200 1 Y 1 C ASN 35  ? OD1 ? C ASN 53  OD1 
201 1 Y 1 C ASN 35  ? ND2 ? C ASN 53  ND2 
202 1 Y 1 C ASP 38  ? CG  ? C ASP 56  CG  
203 1 Y 1 C ASP 38  ? OD1 ? C ASP 56  OD1 
204 1 Y 1 C ASP 38  ? OD2 ? C ASP 56  OD2 
205 1 Y 1 C GLN 44  ? CG  ? C GLN 62  CG  
206 1 Y 1 C GLN 44  ? CD  ? C GLN 62  CD  
207 1 Y 1 C GLN 44  ? OE1 ? C GLN 62  OE1 
208 1 Y 1 C GLN 44  ? NE2 ? C GLN 62  NE2 
209 1 Y 1 C ARG 46  ? CG  ? C ARG 64  CG  
210 1 Y 1 C ARG 46  ? CD  ? C ARG 64  CD  
211 1 Y 1 C ARG 46  ? NE  ? C ARG 64  NE  
212 1 Y 1 C ARG 46  ? CZ  ? C ARG 64  CZ  
213 1 Y 1 C ARG 46  ? NH1 ? C ARG 64  NH1 
214 1 Y 1 C ARG 46  ? NH2 ? C ARG 64  NH2 
215 1 Y 1 C ARG 197 ? CG  ? C ARG 215 CG  
216 1 Y 1 C ARG 197 ? CD  ? C ARG 215 CD  
217 1 Y 1 C ARG 197 ? NE  ? C ARG 215 NE  
218 1 Y 1 C ARG 197 ? CZ  ? C ARG 215 CZ  
219 1 Y 1 C ARG 197 ? NH1 ? C ARG 215 NH1 
220 1 Y 1 C ARG 197 ? NH2 ? C ARG 215 NH2 
221 1 Y 1 C ASP 291 ? CG  ? C ASP 309 CG  
222 1 Y 1 C ASP 291 ? OD1 ? C ASP 309 OD1 
223 1 Y 1 C ASP 291 ? OD2 ? C ASP 309 OD2 
224 1 Y 1 D ARG 13  ? CG  ? D ARG 13  CG  
225 1 Y 1 D ARG 13  ? CD  ? D ARG 13  CD  
226 1 Y 1 D ARG 13  ? NE  ? D ARG 13  NE  
227 1 Y 1 D ARG 13  ? CZ  ? D ARG 13  CZ  
228 1 Y 1 D ARG 13  ? NH1 ? D ARG 13  NH1 
229 1 Y 1 D ARG 13  ? NH2 ? D ARG 13  NH2 
230 1 Y 1 D LYS 14  ? CG  ? D LYS 14  CG  
231 1 Y 1 D LYS 14  ? CD  ? D LYS 14  CD  
232 1 Y 1 D LYS 14  ? CE  ? D LYS 14  CE  
233 1 Y 1 D LYS 14  ? NZ  ? D LYS 14  NZ  
234 1 Y 1 D GLU 17  ? CG  ? D GLU 17  CG  
235 1 Y 1 D GLU 17  ? CD  ? D GLU 17  CD  
236 1 Y 1 D GLU 17  ? OE1 ? D GLU 17  OE1 
237 1 Y 1 D GLU 17  ? OE2 ? D GLU 17  OE2 
238 1 Y 1 D LYS 20  ? CG  ? D LYS 20  CG  
239 1 Y 1 D LYS 20  ? CD  ? D LYS 20  CD  
240 1 Y 1 D LYS 20  ? CE  ? D LYS 20  CE  
241 1 Y 1 D LYS 20  ? NZ  ? D LYS 20  NZ  
242 1 Y 1 D MET 21  ? CG  ? D MET 21  CG  
243 1 Y 1 D MET 21  ? SD  ? D MET 21  SD  
244 1 Y 1 D MET 21  ? CE  ? D MET 21  CE  
245 1 Y 1 D GLU 22  ? CG  ? D GLU 22  CG  
246 1 Y 1 D GLU 22  ? CD  ? D GLU 22  CD  
247 1 Y 1 D GLU 22  ? OE1 ? D GLU 22  OE1 
248 1 Y 1 D GLU 22  ? OE2 ? D GLU 22  OE2 
249 1 Y 1 D ASP 26  ? CG  ? D ASP 26  CG  
250 1 Y 1 D ASP 26  ? OD1 ? D ASP 26  OD1 
251 1 Y 1 D ASP 26  ? OD2 ? D ASP 26  OD2 
252 1 Y 1 D LYS 29  ? CG  ? D LYS 29  CG  
253 1 Y 1 D LYS 29  ? CD  ? D LYS 29  CD  
254 1 Y 1 D LYS 29  ? CE  ? D LYS 29  CE  
255 1 Y 1 D LYS 29  ? NZ  ? D LYS 29  NZ  
256 1 Y 1 D LYS 32  ? CG  ? D LYS 32  CG  
257 1 Y 1 D LYS 32  ? CD  ? D LYS 32  CD  
258 1 Y 1 D LYS 32  ? CE  ? D LYS 32  CE  
259 1 Y 1 D LYS 32  ? NZ  ? D LYS 32  NZ  
260 1 Y 1 D ASP 36  ? CG  ? D ASP 36  CG  
261 1 Y 1 D ASP 36  ? OD1 ? D ASP 36  OD1 
262 1 Y 1 D ASP 36  ? OD2 ? D ASP 36  OD2 
263 1 Y 1 D LYS 46  ? CG  ? D LYS 46  CG  
264 1 Y 1 D LYS 46  ? CD  ? D LYS 46  CD  
265 1 Y 1 D LYS 46  ? CE  ? D LYS 46  CE  
266 1 Y 1 D LYS 46  ? NZ  ? D LYS 46  NZ  
267 1 Y 1 E GLU 42  ? CG  ? E GLU 42  CG  
268 1 Y 1 E GLU 42  ? CD  ? E GLU 42  CD  
269 1 Y 1 E GLU 42  ? OE1 ? E GLU 42  OE1 
270 1 Y 1 E GLU 42  ? OE2 ? E GLU 42  OE2 
271 1 Y 1 E GLU 46  ? CG  ? E GLU 46  CG  
272 1 Y 1 E GLU 46  ? CD  ? E GLU 46  CD  
273 1 Y 1 E GLU 46  ? OE1 ? E GLU 46  OE1 
274 1 Y 1 E GLU 46  ? OE2 ? E GLU 46  OE2 
275 1 Y 1 E LYS 76  ? CG  ? E LYS 76  CG  
276 1 Y 1 E LYS 76  ? CD  ? E LYS 76  CD  
277 1 Y 1 E LYS 76  ? CE  ? E LYS 76  CE  
278 1 Y 1 E LYS 76  ? NZ  ? E LYS 76  NZ  
279 1 Y 1 E GLU 89  ? CG  ? E GLU 89  CG  
280 1 Y 1 E GLU 89  ? CD  ? E GLU 89  CD  
281 1 Y 1 E GLU 89  ? OE1 ? E GLU 89  OE1 
282 1 Y 1 E GLU 89  ? OE2 ? E GLU 89  OE2 
283 1 Y 1 E GLN 130 ? CG  ? E GLN 142 CG  
284 1 Y 1 E GLN 130 ? CD  ? E GLN 142 CD  
285 1 Y 1 E GLN 130 ? OE1 ? E GLN 142 OE1 
286 1 Y 1 E GLN 130 ? NE2 ? E GLN 142 NE2 
287 1 Y 1 E THR 132 ? OG1 ? E THR 144 OG1 
288 1 Y 1 E THR 132 ? CG2 ? E THR 144 CG2 
289 1 Y 1 E THR 138 ? OG1 ? E THR 150 OG1 
290 1 Y 1 E THR 138 ? CG2 ? E THR 150 CG2 
291 1 Y 1 E GLU 141 ? CG  ? E GLU 153 CG  
292 1 Y 1 E GLU 141 ? CD  ? E GLU 153 CD  
293 1 Y 1 E GLU 141 ? OE1 ? E GLU 153 OE1 
294 1 Y 1 E GLU 141 ? OE2 ? E GLU 153 OE2 
295 1 Y 1 E ARG 206 ? CG  ? E ARG 218 CG  
296 1 Y 1 E ARG 206 ? CD  ? E ARG 218 CD  
297 1 Y 1 E ARG 206 ? NE  ? E ARG 218 NE  
298 1 Y 1 E ARG 206 ? CZ  ? E ARG 218 CZ  
299 1 Y 1 E ARG 206 ? NH1 ? E ARG 218 NH1 
300 1 Y 1 E ARG 206 ? NH2 ? E ARG 218 NH2 
301 1 Y 1 E GLU 210 ? CG  ? E GLU 222 CG  
302 1 Y 1 E GLU 210 ? CD  ? E GLU 222 CD  
303 1 Y 1 E GLU 210 ? OE1 ? E GLU 222 OE1 
304 1 Y 1 E GLU 210 ? OE2 ? E GLU 222 OE2 
305 1 Y 1 E GLU 234 ? CG  ? E GLU 246 CG  
306 1 Y 1 E GLU 234 ? CD  ? E GLU 246 CD  
307 1 Y 1 E GLU 234 ? OE1 ? E GLU 246 OE1 
308 1 Y 1 E GLU 234 ? OE2 ? E GLU 246 OE2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9AS4 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9AS4 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9AS4 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9AS4 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            3.06 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'REAL-SPACE (WEIGHTED MAP SUM AT ATOM CENTERS)' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.006 ? 1942 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 1.112 ? 2652 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 7.577 ? 257  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.041 ? 331  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.009 ? 309  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9AS4 
_struct.title                        
;Global reconstruction of 5-HT2AR bound to LSD in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
;
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9AS4 
_struct_keywords.text            'GPCR, G-protein Coupled Receptor, 5-HT2AR, serotonin, psychedelics, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
F N N 6 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP 5HT2A_HUMAN P28223 ? 1 
;MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALL
TAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFST
ASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQK
ACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYK
ENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
;
1 
2 PDB 9AS4        9AS4   ? 2 ? 1 
3 UNP GBB1_HUMAN  P62873 ? 3 
;SELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLII
WDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSS
GDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAF
ATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVT
DDGMAVATGSWDSFLKIWN
;
2 
4 UNP GBG2_HUMAN  P59768 ? 4 MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 1 
5 PDB 9AS4        9AS4   ? 5 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9AS4 A 1  ? 471 ? P28223 1 ? 471 ? 1 471 
2 2 9AS4 B 1  ? 246 ? 9AS4   1 ? 246 ? 1 246 
3 3 9AS4 C 20 ? 358 ? P62873 2 ? 340 ? 2 340 
4 4 9AS4 D 1  ? 71  ? P59768 1 ? 71  ? 1 71  
5 5 9AS4 E 1  ? 267 ? 9AS4   1 ? 255 ? 1 255 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
3 9AS4 MET C 1  ? UNP P62873 ? ? 'expression tag' -17 1  
3 9AS4 HIS C 2  ? UNP P62873 ? ? 'expression tag' -16 2  
3 9AS4 HIS C 3  ? UNP P62873 ? ? 'expression tag' -15 3  
3 9AS4 HIS C 4  ? UNP P62873 ? ? 'expression tag' -14 4  
3 9AS4 HIS C 5  ? UNP P62873 ? ? 'expression tag' -13 5  
3 9AS4 HIS C 6  ? UNP P62873 ? ? 'expression tag' -12 6  
3 9AS4 HIS C 7  ? UNP P62873 ? ? 'expression tag' -11 7  
3 9AS4 LEU C 8  ? UNP P62873 ? ? 'expression tag' -10 8  
3 9AS4 GLU C 9  ? UNP P62873 ? ? 'expression tag' -9  9  
3 9AS4 VAL C 10 ? UNP P62873 ? ? 'expression tag' -8  10 
3 9AS4 LEU C 11 ? UNP P62873 ? ? 'expression tag' -7  11 
3 9AS4 PHE C 12 ? UNP P62873 ? ? 'expression tag' -6  12 
3 9AS4 GLN C 13 ? UNP P62873 ? ? 'expression tag' -5  13 
3 9AS4 GLY C 14 ? UNP P62873 ? ? 'expression tag' -4  14 
3 9AS4 PRO C 15 ? UNP P62873 ? ? 'expression tag' -3  15 
3 9AS4 GLY C 16 ? UNP P62873 ? ? 'expression tag' -2  16 
3 9AS4 SER C 17 ? UNP P62873 ? ? 'expression tag' -1  17 
3 9AS4 SER C 18 ? UNP P62873 ? ? 'expression tag' 0   18 
3 9AS4 GLY C 19 ? UNP P62873 ? ? 'expression tag' 1   19 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   pentameric 
_pdbx_struct_assembly.oligomeric_count     5 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 VAL A 84  ? VAL A 99  ? VAL A 84  VAL A 99  1 ? 16 
HELX_P HELX_P2  AA2 THR A 109 ? LEU A 122 ? THR A 109 LEU A 122 1 ? 14 
HELX_P HELX_P3  AA3 VAL A 127 ? TYR A 137 ? VAL A 127 TYR A 137 1 ? 11 
HELX_P HELX_P4  AA4 LEU A 147 ? ASN A 179 ? LEU A 147 ASN A 179 1 ? 33 
HELX_P HELX_P5  AA5 ASN A 179 ? PHE A 186 ? ASN A 179 PHE A 186 1 ? 8  
HELX_P HELX_P6  AA6 THR A 190 ? SER A 207 ? THR A 190 SER A 207 1 ? 18 
HELX_P HELX_P7  AA7 MET A 208 ? PHE A 213 ? MET A 208 PHE A 213 1 ? 6  
HELX_P HELX_P8  AA8 ASN A 233 ? SER A 239 ? ASN A 233 SER A 239 1 ? 7  
HELX_P HELX_P9  AA9 PHE A 243 ? LEU A 261 ? PHE A 243 LEU A 261 1 ? 19 
HELX_P HELX_P10 AB1 SER A 316 ? VAL A 347 ? SER A 316 VAL A 347 1 ? 32 
HELX_P HELX_P11 AB2 GLU A 355 ? LEU A 382 ? GLU A 355 LEU A 382 1 ? 28 
HELX_P HELX_P12 AB3 ASN A 384 ? ARG A 393 ? ASN A 384 ARG A 393 1 ? 10 
HELX_P HELX_P13 AB4 SER B 6   ? THR B 33  ? SER B 6   THR B 33  1 ? 28 
HELX_P HELX_P14 AB5 GLY B 45  ? ILE B 49  ? GLY B 45  ILE B 49  5 ? 5  
HELX_P HELX_P15 AB6 TYR B 115 ? ASN B 130 ? TYR B 115 ASN B 130 1 ? 16 
HELX_P HELX_P16 AB7 LYS B 145 ? GLY B 156 ? LYS B 145 GLY B 156 1 ? 12 
HELX_P HELX_P17 AB8 LYS B 159 ? PHE B 164 ? LYS B 159 PHE B 164 1 ? 6  
HELX_P HELX_P18 AB9 PHE B 164 ? ARG B 169 ? PHE B 164 ARG B 169 1 ? 6  
HELX_P HELX_P19 AC1 ASP B 183 ? ALA B 203 ? ASP B 183 ALA B 203 1 ? 21 
HELX_P HELX_P20 AC2 ASN B 223 ? TYR B 243 ? ASN B 223 TYR B 243 1 ? 21 
HELX_P HELX_P21 AC3 ALA C 29  ? ALA C 44  ? ALA C 11  ALA C 26  1 ? 16 
HELX_P HELX_P22 AC4 THR C 47  ? ASN C 53  ? THR C 29  ASN C 35  1 ? 7  
HELX_P HELX_P23 AC5 ARG D 13  ? ASN D 24  ? ARG D 13  ASN D 24  1 ? 12 
HELX_P HELX_P24 AC6 LYS D 29  ? HIS D 44  ? LYS D 29  HIS D 44  1 ? 16 
HELX_P HELX_P25 AC7 SER E 53  ? GLY E 56  ? SER E 53  GLY E 56  5 ? 4  
HELX_P HELX_P26 AC8 ARG E 87  ? THR E 91  ? ARG E 87  THR E 91  5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 148 SG ? ? ? 1_555 A CYS 227 SG ? ? A CYS 148 A CYS 227 1_555 ? ? ? ? ? ? ? 2.029 ? ? 
disulf2 disulf ? ? E CYS 22  SG ? ? ? 1_555 E CYS 96  SG ? ? E CYS 22  E CYS 96  1_555 ? ? ? ? ? ? ? 2.045 ? ? 
disulf3 disulf ? ? E CYS 159 SG ? ? ? 1_555 E CYS 229 SG ? ? E CYS 147 E CYS 217 1_555 ? ? ? ? ? ? ? 2.033 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 148 ? CYS A 227 ? CYS A 148 ? 1_555 CYS A 227 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS E 22  ? CYS E 96  ? CYS E 22  ? 1_555 CYS E 96  ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS E 159 ? CYS E 229 ? CYS E 147 ? 1_555 CYS E 217 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          TYR 
_struct_mon_prot_cis.label_seq_id           235 
_struct_mon_prot_cis.label_asym_id          E 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           TYR 
_struct_mon_prot_cis.auth_seq_id            223 
_struct_mon_prot_cis.auth_asym_id           E 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    236 
_struct_mon_prot_cis.pdbx_label_asym_id_2   E 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     224 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    E 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       -1.50 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 4 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 4 ? 
AA7 ? 4 ? 
AA8 ? 4 ? 
AA9 ? 4 ? 
AB1 ? 5 ? 
AB2 ? 3 ? 
AB3 ? 2 ? 
AB4 ? 2 ? 
AB5 ? 3 ? 
AB6 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? parallel      
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 4 5 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB4 1 2 ? parallel      
AB5 1 2 ? anti-parallel 
AB5 2 3 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB6 2 3 ? anti-parallel 
AB6 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 PHE B 70  ? VAL B 76  ? PHE B 70  VAL B 76  
AA1 2 VAL B 79  ? ASP B 85  ? VAL B 79  ASP B 85  
AA1 3 LEU B 34  ? LEU B 39  ? LEU B 34  LEU B 39  
AA1 4 ALA B 105 ? ASP B 111 ? ALA B 105 ASP B 111 
AA1 5 SER B 138 ? ASN B 144 ? SER B 138 ASN B 144 
AA1 6 CYS B 211 ? THR B 216 ? CYS B 211 THR B 216 
AA2 1 THR C 65  ? LEU C 69  ? THR C 47  LEU C 51  
AA2 2 LEU C 354 ? TRP C 357 ? LEU C 336 TRP C 339 
AA2 3 VAL C 345 ? SER C 349 ? VAL C 327 SER C 331 
AA2 4 VAL C 333 ? VAL C 338 ? VAL C 315 VAL C 320 
AA3 1 ILE C 76  ? TRP C 81  ? ILE C 58  TRP C 63  
AA3 2 LEU C 87  ? SER C 92  ? LEU C 69  SER C 74  
AA3 3 LYS C 96  ? ASP C 101 ? LYS C 78  ASP C 83  
AA3 4 ASN C 106 ? PRO C 112 ? ASN C 88  PRO C 94  
AA4 1 THR C 120 ? TYR C 123 ? THR C 102 TYR C 105 
AA4 2 TYR C 129 ? GLY C 133 ? TYR C 111 GLY C 115 
AA4 3 CYS C 139 ? ASN C 143 ? CYS C 121 ASN C 125 
AA4 4 ARG C 152 ? LEU C 157 ? ARG C 134 LEU C 139 
AA5 1 LEU C 164 ? PHE C 169 ? LEU C 146 PHE C 151 
AA5 2 GLN C 174 ? SER C 179 ? GLN C 156 SER C 161 
AA5 3 CYS C 184 ? ASP C 188 ? CYS C 166 ASP C 170 
AA5 4 GLN C 193 ? PHE C 198 ? GLN C 175 PHE C 180 
AA6 1 VAL C 205 ? LEU C 210 ? VAL C 187 LEU C 192 
AA6 2 LEU C 216 ? ALA C 221 ? LEU C 198 ALA C 203 
AA6 3 ALA C 226 ? ASP C 230 ? ALA C 208 ASP C 212 
AA6 4 MET C 235 ? PHE C 240 ? MET C 217 PHE C 222 
AA7 1 ILE C 247 ? PHE C 252 ? ILE C 229 PHE C 234 
AA7 2 ALA C 258 ? SER C 263 ? ALA C 240 SER C 245 
AA7 3 CYS C 268 ? ASP C 272 ? CYS C 250 ASP C 254 
AA7 4 GLU C 278 ? TYR C 282 ? GLU C 260 TYR C 264 
AA8 1 ILE C 291 ? PHE C 296 ? ILE C 273 PHE C 278 
AA8 2 LEU C 302 ? TYR C 307 ? LEU C 284 TYR C 289 
AA8 3 CYS C 312 ? ASP C 316 ? CYS C 294 ASP C 298 
AA8 4 ASP C 321 ? LEU C 326 ? ASP C 303 LEU C 308 
AA9 1 GLN E 3   ? SER E 7   ? GLN E 3   SER E 7   
AA9 2 ARG E 18  ? SER E 25  ? ARG E 18  SER E 25  
AA9 3 THR E 78  ? MET E 83  ? THR E 78  MET E 83  
AA9 4 PHE E 68  ? ASP E 73  ? PHE E 68  ASP E 73  
AB1 1 GLY E 10  ? LEU E 11  ? GLY E 10  LEU E 11  
AB1 2 THR E 115 ? THR E 118 ? THR E 115 THR E 118 
AB1 3 ALA E 92  ? TYR E 94  ? ALA E 92  TYR E 94  
AB1 4 ARG E 38  ? GLN E 39  ? ARG E 38  GLN E 39  
AB1 5 LEU E 45  ? GLU E 46  ? LEU E 45  GLU E 46  
AB2 1 GLY E 33  ? MET E 34  ? GLY E 33  MET E 34  
AB2 2 VAL E 97  ? SER E 99  ? VAL E 97  SER E 99  
AB2 3 PHE E 110 ? TRP E 111 ? PHE E 110 TRP E 111 
AB3 1 ALA E 49  ? ILE E 51  ? ALA E 49  ILE E 51  
AB3 2 ILE E 58  ? TYR E 60  ? ILE E 58  TYR E 60  
AB4 1 SER E 146 ? PRO E 148 ? SER E 134 PRO E 136 
AB4 2 LYS E 244 ? GLU E 246 ? LYS E 232 GLU E 234 
AB5 1 VAL E 155 ? ARG E 160 ? VAL E 143 ARG E 148 
AB5 2 ALA E 211 ? ILE E 216 ? ALA E 199 ILE E 204 
AB5 3 PHE E 203 ? SER E 208 ? PHE E 191 SER E 196 
AB6 1 ASN E 194 ? LEU E 195 ? ASN E 182 LEU E 183 
AB6 2 GLN E 186 ? TYR E 190 ? GLN E 174 TYR E 178 
AB6 3 LEU E 174 ? GLN E 179 ? LEU E 162 GLN E 167 
AB6 4 VAL E 226 ? GLN E 231 ? VAL E 214 GLN E 219 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N PHE B 70  ? N PHE B 70  O ASP B 85  ? O ASP B 85  
AA1 2 3 O HIS B 82  ? O HIS B 82  N LEU B 36  ? N LEU B 36  
AA1 3 4 N LEU B 37  ? N LEU B 37  O ILE B 107 ? O ILE B 107 
AA1 4 5 N ILE B 106 ? N ILE B 106 O ILE B 140 ? O ILE B 140 
AA1 5 6 N LEU B 143 ? N LEU B 143 O HIS B 214 ? O HIS B 214 
AA2 1 2 N ARG C 67  ? N ARG C 49  O ILE C 356 ? O ILE C 338 
AA2 2 3 O TRP C 357 ? O TRP C 339 N VAL C 345 ? N VAL C 327 
AA2 3 4 O ALA C 346 ? O ALA C 328 N GLY C 337 ? N GLY C 319 
AA3 1 2 N ALA C 78  ? N ALA C 60  O ALA C 91  ? O ALA C 73  
AA3 2 3 N LEU C 88  ? N LEU C 70  O TRP C 100 ? O TRP C 82  
AA3 3 4 N ASP C 101 ? N ASP C 83  O ASN C 106 ? O ASN C 88  
AA4 1 2 N ALA C 122 ? N ALA C 104 O ALA C 131 ? O ALA C 113 
AA4 2 3 N VAL C 130 ? N VAL C 112 O TYR C 142 ? O TYR C 124 
AA4 3 4 N CYS C 139 ? N CYS C 121 O LEU C 157 ? O LEU C 139 
AA5 1 2 N ARG C 168 ? N ARG C 150 O VAL C 176 ? O VAL C 158 
AA5 2 3 N ILE C 175 ? N ILE C 157 O TRP C 187 ? O TRP C 169 
AA5 3 4 N CYS C 184 ? N CYS C 166 O PHE C 198 ? O PHE C 180 
AA6 1 2 N SER C 209 ? N SER C 191 O VAL C 218 ? O VAL C 200 
AA6 2 3 N PHE C 217 ? N PHE C 199 O TRP C 229 ? O TRP C 211 
AA6 3 4 N ALA C 226 ? N ALA C 208 O PHE C 240 ? O PHE C 222 
AA7 1 2 N ALA C 249 ? N ALA C 231 O GLY C 262 ? O GLY C 244 
AA7 2 3 N PHE C 259 ? N PHE C 241 O PHE C 271 ? O PHE C 253 
AA7 3 4 N CYS C 268 ? N CYS C 250 O TYR C 282 ? O TYR C 264 
AA8 1 2 N SER C 293 ? N SER C 275 O GLY C 306 ? O GLY C 288 
AA8 2 3 N LEU C 303 ? N LEU C 285 O TRP C 315 ? O TRP C 297 
AA8 3 4 N ASP C 316 ? N ASP C 298 O ASP C 321 ? O ASP C 303 
AA9 1 2 N SER E 7   ? N SER E 7   O SER E 21  ? O SER E 21  
AA9 2 3 N LEU E 20  ? N LEU E 20  O LEU E 81  ? O LEU E 81  
AA9 3 4 O GLN E 82  ? O GLN E 82  N THR E 69  ? N THR E 69  
AB1 1 2 N GLY E 10  ? N GLY E 10  O THR E 116 ? O THR E 116 
AB1 2 3 O LEU E 117 ? O LEU E 117 N ALA E 92  ? N ALA E 92  
AB1 3 4 O MET E 93  ? O MET E 93  N GLN E 39  ? N GLN E 39  
AB1 4 5 N ARG E 38  ? N ARG E 38  O GLU E 46  ? O GLU E 46  
AB2 1 2 N GLY E 33  ? N GLY E 33  O SER E 99  ? O SER E 99  
AB2 2 3 N ARG E 98  ? N ARG E 98  O PHE E 110 ? O PHE E 110 
AB3 1 2 N TYR E 50  ? N TYR E 50  O TYR E 59  ? O TYR E 59  
AB4 1 2 N VAL E 147 ? N VAL E 135 O GLU E 246 ? O GLU E 234 
AB5 1 2 N VAL E 155 ? N VAL E 143 O ILE E 216 ? O ILE E 204 
AB5 2 3 O THR E 215 ? O THR E 203 N SER E 204 ? N SER E 192 
AB6 1 2 O ASN E 194 ? O ASN E 182 N TYR E 190 ? N TYR E 178 
AB6 2 3 O LEU E 188 ? O LEU E 176 N TRP E 176 ? N TRP E 164 
AB6 3 4 N TYR E 175 ? N TYR E 163 O MET E 230 ? O MET E 218 
# 
_pdbx_entry_details.entry_id                   9AS4 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 TYR A 139 ? ? 74.44   -4.84   
2  1 SER A 219 ? ? -140.79 -3.84   
3  1 LYS A 220 ? ? -90.05  -64.31  
4  1 PHE A 222 ? ? -171.71 -171.48 
5  1 PHE A 243 ? ? -121.19 -50.48  
6  1 ASN C 36  ? ? -102.05 68.16   
7  1 THR C 47  ? ? -68.21  93.58   
8  1 SER C 67  ? ? 80.57   -3.82   
9  1 GLU C 130 ? ? 82.71   -3.18   
10 1 THR C 196 ? ? 78.22   -9.80   
11 1 MET E 180 ? ? 76.39   -15.78  
12 1 THR E 198 ? ? 77.21   -9.69   
13 1 GLU E 210 ? ? 78.47   -0.24   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9AS4 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9AS4 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.06 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               168657 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 '5-HT2AR in complex with mini-Gq' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4, 5' 
# 
_em_imaging.entry_id                        9AS4 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TALOS ARCTICA' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            200 
_em_imaging.illumination_mode               OTHER 
_em_imaging.mode                            OTHER 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             160 
_em_imaging.nominal_defocus_max             2600 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9AS4 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE-PROPANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9AS4 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A ASP 2   ? A ASP 2   
3   1 Y 1 A ILE 3   ? A ILE 3   
4   1 Y 1 A LEU 4   ? A LEU 4   
5   1 Y 1 A CYS 5   ? A CYS 5   
6   1 Y 1 A GLU 6   ? A GLU 6   
7   1 Y 1 A GLU 7   ? A GLU 7   
8   1 Y 1 A ASN 8   ? A ASN 8   
9   1 Y 1 A THR 9   ? A THR 9   
10  1 Y 1 A SER 10  ? A SER 10  
11  1 Y 1 A LEU 11  ? A LEU 11  
12  1 Y 1 A SER 12  ? A SER 12  
13  1 Y 1 A SER 13  ? A SER 13  
14  1 Y 1 A THR 14  ? A THR 14  
15  1 Y 1 A THR 15  ? A THR 15  
16  1 Y 1 A ASN 16  ? A ASN 16  
17  1 Y 1 A SER 17  ? A SER 17  
18  1 Y 1 A LEU 18  ? A LEU 18  
19  1 Y 1 A MET 19  ? A MET 19  
20  1 Y 1 A GLN 20  ? A GLN 20  
21  1 Y 1 A LEU 21  ? A LEU 21  
22  1 Y 1 A ASN 22  ? A ASN 22  
23  1 Y 1 A ASP 23  ? A ASP 23  
24  1 Y 1 A ASP 24  ? A ASP 24  
25  1 Y 1 A THR 25  ? A THR 25  
26  1 Y 1 A ARG 26  ? A ARG 26  
27  1 Y 1 A LEU 27  ? A LEU 27  
28  1 Y 1 A TYR 28  ? A TYR 28  
29  1 Y 1 A SER 29  ? A SER 29  
30  1 Y 1 A ASN 30  ? A ASN 30  
31  1 Y 1 A ASP 31  ? A ASP 31  
32  1 Y 1 A PHE 32  ? A PHE 32  
33  1 Y 1 A ASN 33  ? A ASN 33  
34  1 Y 1 A SER 34  ? A SER 34  
35  1 Y 1 A GLY 35  ? A GLY 35  
36  1 Y 1 A GLU 36  ? A GLU 36  
37  1 Y 1 A ALA 37  ? A ALA 37  
38  1 Y 1 A ASN 38  ? A ASN 38  
39  1 Y 1 A THR 39  ? A THR 39  
40  1 Y 1 A SER 40  ? A SER 40  
41  1 Y 1 A ASP 41  ? A ASP 41  
42  1 Y 1 A ALA 42  ? A ALA 42  
43  1 Y 1 A PHE 43  ? A PHE 43  
44  1 Y 1 A ASN 44  ? A ASN 44  
45  1 Y 1 A TRP 45  ? A TRP 45  
46  1 Y 1 A THR 46  ? A THR 46  
47  1 Y 1 A VAL 47  ? A VAL 47  
48  1 Y 1 A ASP 48  ? A ASP 48  
49  1 Y 1 A SER 49  ? A SER 49  
50  1 Y 1 A GLU 50  ? A GLU 50  
51  1 Y 1 A ASN 51  ? A ASN 51  
52  1 Y 1 A ARG 52  ? A ARG 52  
53  1 Y 1 A THR 53  ? A THR 53  
54  1 Y 1 A ASN 54  ? A ASN 54  
55  1 Y 1 A LEU 55  ? A LEU 55  
56  1 Y 1 A SER 56  ? A SER 56  
57  1 Y 1 A CYS 57  ? A CYS 57  
58  1 Y 1 A GLU 58  ? A GLU 58  
59  1 Y 1 A GLY 59  ? A GLY 59  
60  1 Y 1 A CYS 60  ? A CYS 60  
61  1 Y 1 A LEU 61  ? A LEU 61  
62  1 Y 1 A SER 62  ? A SER 62  
63  1 Y 1 A PRO 63  ? A PRO 63  
64  1 Y 1 A SER 64  ? A SER 64  
65  1 Y 1 A CYS 65  ? A CYS 65  
66  1 Y 1 A LEU 66  ? A LEU 66  
67  1 Y 1 A SER 67  ? A SER 67  
68  1 Y 1 A LEU 68  ? A LEU 68  
69  1 Y 1 A LEU 69  ? A LEU 69  
70  1 Y 1 A HIS 70  ? A HIS 70  
71  1 Y 1 A LEU 71  ? A LEU 71  
72  1 Y 1 A GLN 72  ? A GLN 72  
73  1 Y 1 A GLU 73  ? A GLU 73  
74  1 Y 1 A LYS 74  ? A LYS 74  
75  1 Y 1 A ASN 75  ? A ASN 75  
76  1 Y 1 A TRP 76  ? A TRP 76  
77  1 Y 1 A SER 77  ? A SER 77  
78  1 Y 1 A ALA 78  ? A ALA 78  
79  1 Y 1 A LEU 79  ? A LEU 79  
80  1 Y 1 A LEU 80  ? A LEU 80  
81  1 Y 1 A THR 81  ? A THR 81  
82  1 Y 1 A ALA 82  ? A ALA 82  
83  1 Y 1 A VAL 83  ? A VAL 83  
84  1 Y 1 A SER 100 ? A SER 100 
85  1 Y 1 A LEU 101 ? A LEU 101 
86  1 Y 1 A GLU 102 ? A GLU 102 
87  1 Y 1 A LYS 103 ? A LYS 103 
88  1 Y 1 A LYS 104 ? A LYS 104 
89  1 Y 1 A LEU 143 ? A LEU 143 
90  1 Y 1 A PRO 144 ? A PRO 144 
91  1 Y 1 A LYS 263 ? A LYS 263 
92  1 Y 1 A GLU 264 ? A GLU 264 
93  1 Y 1 A ALA 265 ? A ALA 265 
94  1 Y 1 A THR 266 ? A THR 266 
95  1 Y 1 A LEU 267 ? A LEU 267 
96  1 Y 1 A CYS 268 ? A CYS 268 
97  1 Y 1 A VAL 269 ? A VAL 269 
98  1 Y 1 A SER 270 ? A SER 270 
99  1 Y 1 A ASP 271 ? A ASP 271 
100 1 Y 1 A LEU 272 ? A LEU 272 
101 1 Y 1 A GLY 273 ? A GLY 273 
102 1 Y 1 A THR 274 ? A THR 274 
103 1 Y 1 A ARG 275 ? A ARG 275 
104 1 Y 1 A ALA 276 ? A ALA 276 
105 1 Y 1 A LYS 277 ? A LYS 277 
106 1 Y 1 A LEU 278 ? A LEU 278 
107 1 Y 1 A ALA 279 ? A ALA 279 
108 1 Y 1 A SER 280 ? A SER 280 
109 1 Y 1 A PHE 281 ? A PHE 281 
110 1 Y 1 A SER 282 ? A SER 282 
111 1 Y 1 A PHE 283 ? A PHE 283 
112 1 Y 1 A LEU 284 ? A LEU 284 
113 1 Y 1 A PRO 285 ? A PRO 285 
114 1 Y 1 A GLN 286 ? A GLN 286 
115 1 Y 1 A SER 287 ? A SER 287 
116 1 Y 1 A SER 288 ? A SER 288 
117 1 Y 1 A LEU 289 ? A LEU 289 
118 1 Y 1 A SER 290 ? A SER 290 
119 1 Y 1 A SER 291 ? A SER 291 
120 1 Y 1 A GLU 292 ? A GLU 292 
121 1 Y 1 A LYS 293 ? A LYS 293 
122 1 Y 1 A LEU 294 ? A LEU 294 
123 1 Y 1 A PHE 295 ? A PHE 295 
124 1 Y 1 A GLN 296 ? A GLN 296 
125 1 Y 1 A ARG 297 ? A ARG 297 
126 1 Y 1 A SER 298 ? A SER 298 
127 1 Y 1 A ILE 299 ? A ILE 299 
128 1 Y 1 A HIS 300 ? A HIS 300 
129 1 Y 1 A ARG 301 ? A ARG 301 
130 1 Y 1 A GLU 302 ? A GLU 302 
131 1 Y 1 A PRO 303 ? A PRO 303 
132 1 Y 1 A GLY 304 ? A GLY 304 
133 1 Y 1 A SER 305 ? A SER 305 
134 1 Y 1 A TYR 306 ? A TYR 306 
135 1 Y 1 A THR 307 ? A THR 307 
136 1 Y 1 A GLY 308 ? A GLY 308 
137 1 Y 1 A ARG 309 ? A ARG 309 
138 1 Y 1 A ARG 310 ? A ARG 310 
139 1 Y 1 A THR 311 ? A THR 311 
140 1 Y 1 A MET 312 ? A MET 312 
141 1 Y 1 A GLN 313 ? A GLN 313 
142 1 Y 1 A SER 314 ? A SER 314 
143 1 Y 1 A ILE 348 ? A ILE 348 
144 1 Y 1 A CYS 349 ? A CYS 349 
145 1 Y 1 A LYS 350 ? A LYS 350 
146 1 Y 1 A GLU 351 ? A GLU 351 
147 1 Y 1 A SER 352 ? A SER 352 
148 1 Y 1 A CYS 353 ? A CYS 353 
149 1 Y 1 A TYR 394 ? A TYR 394 
150 1 Y 1 A ILE 395 ? A ILE 395 
151 1 Y 1 A GLN 396 ? A GLN 396 
152 1 Y 1 A CYS 397 ? A CYS 397 
153 1 Y 1 A GLN 398 ? A GLN 398 
154 1 Y 1 A TYR 399 ? A TYR 399 
155 1 Y 1 A LYS 400 ? A LYS 400 
156 1 Y 1 A GLU 401 ? A GLU 401 
157 1 Y 1 A ASN 402 ? A ASN 402 
158 1 Y 1 A LYS 403 ? A LYS 403 
159 1 Y 1 A LYS 404 ? A LYS 404 
160 1 Y 1 A PRO 405 ? A PRO 405 
161 1 Y 1 A LEU 406 ? A LEU 406 
162 1 Y 1 A GLN 407 ? A GLN 407 
163 1 Y 1 A LEU 408 ? A LEU 408 
164 1 Y 1 A ILE 409 ? A ILE 409 
165 1 Y 1 A LEU 410 ? A LEU 410 
166 1 Y 1 A VAL 411 ? A VAL 411 
167 1 Y 1 A ASN 412 ? A ASN 412 
168 1 Y 1 A THR 413 ? A THR 413 
169 1 Y 1 A ILE 414 ? A ILE 414 
170 1 Y 1 A PRO 415 ? A PRO 415 
171 1 Y 1 A ALA 416 ? A ALA 416 
172 1 Y 1 A LEU 417 ? A LEU 417 
173 1 Y 1 A ALA 418 ? A ALA 418 
174 1 Y 1 A TYR 419 ? A TYR 419 
175 1 Y 1 A LYS 420 ? A LYS 420 
176 1 Y 1 A SER 421 ? A SER 421 
177 1 Y 1 A SER 422 ? A SER 422 
178 1 Y 1 A GLN 423 ? A GLN 423 
179 1 Y 1 A LEU 424 ? A LEU 424 
180 1 Y 1 A GLN 425 ? A GLN 425 
181 1 Y 1 A MET 426 ? A MET 426 
182 1 Y 1 A GLY 427 ? A GLY 427 
183 1 Y 1 A GLN 428 ? A GLN 428 
184 1 Y 1 A LYS 429 ? A LYS 429 
185 1 Y 1 A LYS 430 ? A LYS 430 
186 1 Y 1 A ASN 431 ? A ASN 431 
187 1 Y 1 A SER 432 ? A SER 432 
188 1 Y 1 A LYS 433 ? A LYS 433 
189 1 Y 1 A GLN 434 ? A GLN 434 
190 1 Y 1 A ASP 435 ? A ASP 435 
191 1 Y 1 A ALA 436 ? A ALA 436 
192 1 Y 1 A LYS 437 ? A LYS 437 
193 1 Y 1 A THR 438 ? A THR 438 
194 1 Y 1 A THR 439 ? A THR 439 
195 1 Y 1 A ASP 440 ? A ASP 440 
196 1 Y 1 A ASN 441 ? A ASN 441 
197 1 Y 1 A ASP 442 ? A ASP 442 
198 1 Y 1 A CYS 443 ? A CYS 443 
199 1 Y 1 A SER 444 ? A SER 444 
200 1 Y 1 A MET 445 ? A MET 445 
201 1 Y 1 A VAL 446 ? A VAL 446 
202 1 Y 1 A ALA 447 ? A ALA 447 
203 1 Y 1 A LEU 448 ? A LEU 448 
204 1 Y 1 A GLY 449 ? A GLY 449 
205 1 Y 1 A LYS 450 ? A LYS 450 
206 1 Y 1 A GLN 451 ? A GLN 451 
207 1 Y 1 A HIS 452 ? A HIS 452 
208 1 Y 1 A SER 453 ? A SER 453 
209 1 Y 1 A GLU 454 ? A GLU 454 
210 1 Y 1 A GLU 455 ? A GLU 455 
211 1 Y 1 A ALA 456 ? A ALA 456 
212 1 Y 1 A SER 457 ? A SER 457 
213 1 Y 1 A LYS 458 ? A LYS 458 
214 1 Y 1 A ASP 459 ? A ASP 459 
215 1 Y 1 A ASN 460 ? A ASN 460 
216 1 Y 1 A SER 461 ? A SER 461 
217 1 Y 1 A ASP 462 ? A ASP 462 
218 1 Y 1 A GLY 463 ? A GLY 463 
219 1 Y 1 A VAL 464 ? A VAL 464 
220 1 Y 1 A ASN 465 ? A ASN 465 
221 1 Y 1 A GLU 466 ? A GLU 466 
222 1 Y 1 A LYS 467 ? A LYS 467 
223 1 Y 1 A VAL 468 ? A VAL 468 
224 1 Y 1 A SER 469 ? A SER 469 
225 1 Y 1 A CYS 470 ? A CYS 470 
226 1 Y 1 A VAL 471 ? A VAL 471 
227 1 Y 1 B MET 1   ? B MET 1   
228 1 Y 1 B GLY 2   ? B GLY 2   
229 1 Y 1 B SER 3   ? B SER 3   
230 1 Y 1 B ILE 55  ? B ILE 55  
231 1 Y 1 B LEU 56  ? B LEU 56  
232 1 Y 1 B HIS 57  ? B HIS 57  
233 1 Y 1 B GLY 58  ? B GLY 58  
234 1 Y 1 B GLY 59  ? B GLY 59  
235 1 Y 1 B SER 60  ? B SER 60  
236 1 Y 1 B GLY 61  ? B GLY 61  
237 1 Y 1 B GLY 62  ? B GLY 62  
238 1 Y 1 B SER 63  ? B SER 63  
239 1 Y 1 B GLY 64  ? B GLY 64  
240 1 Y 1 B GLY 65  ? B GLY 65  
241 1 Y 1 B GLU 174 ? B GLU 174 
242 1 Y 1 B ASP 175 ? B ASP 175 
243 1 Y 1 B ALA 176 ? B ALA 176 
244 1 Y 1 B THR 177 ? B THR 177 
245 1 Y 1 B PRO 178 ? B PRO 178 
246 1 Y 1 B GLU 179 ? B GLU 179 
247 1 Y 1 B PRO 180 ? B PRO 180 
248 1 Y 1 B GLY 181 ? B GLY 181 
249 1 Y 1 C MET -17 ? C MET 1   
250 1 Y 1 C HIS -16 ? C HIS 2   
251 1 Y 1 C HIS -15 ? C HIS 3   
252 1 Y 1 C HIS -14 ? C HIS 4   
253 1 Y 1 C HIS -13 ? C HIS 5   
254 1 Y 1 C HIS -12 ? C HIS 6   
255 1 Y 1 C HIS -11 ? C HIS 7   
256 1 Y 1 C LEU -10 ? C LEU 8   
257 1 Y 1 C GLU -9  ? C GLU 9   
258 1 Y 1 C VAL -8  ? C VAL 10  
259 1 Y 1 C LEU -7  ? C LEU 11  
260 1 Y 1 C PHE -6  ? C PHE 12  
261 1 Y 1 C GLN -5  ? C GLN 13  
262 1 Y 1 C GLY -4  ? C GLY 14  
263 1 Y 1 C PRO -3  ? C PRO 15  
264 1 Y 1 C GLY -2  ? C GLY 16  
265 1 Y 1 C SER -1  ? C SER 17  
266 1 Y 1 C SER 0   ? C SER 18  
267 1 Y 1 C GLY 1   ? C GLY 19  
268 1 Y 1 C SER 2   ? C SER 20  
269 1 Y 1 C GLU 3   ? C GLU 21  
270 1 Y 1 C LEU 4   ? C LEU 22  
271 1 Y 1 C ASP 5   ? C ASP 23  
272 1 Y 1 C GLN 6   ? C GLN 24  
273 1 Y 1 C LEU 7   ? C LEU 25  
274 1 Y 1 C ARG 8   ? C ARG 26  
275 1 Y 1 C GLN 9   ? C GLN 27  
276 1 Y 1 D MET 1   ? D MET 1   
277 1 Y 1 D ALA 2   ? D ALA 2   
278 1 Y 1 D SER 3   ? D SER 3   
279 1 Y 1 D ASN 4   ? D ASN 4   
280 1 Y 1 D ASN 5   ? D ASN 5   
281 1 Y 1 D THR 6   ? D THR 6   
282 1 Y 1 D ALA 7   ? D ALA 7   
283 1 Y 1 D SER 8   ? D SER 8   
284 1 Y 1 D ILE 9   ? D ILE 9   
285 1 Y 1 D ALA 10  ? D ALA 10  
286 1 Y 1 D GLN 11  ? D GLN 11  
287 1 Y 1 D ARG 62  ? D ARG 62  
288 1 Y 1 D GLU 63  ? D GLU 63  
289 1 Y 1 D LYS 64  ? D LYS 64  
290 1 Y 1 D LYS 65  ? D LYS 65  
291 1 Y 1 D PHE 66  ? D PHE 66  
292 1 Y 1 D PHE 67  ? D PHE 67  
293 1 Y 1 D CYS 68  ? D CYS 68  
294 1 Y 1 D ALA 69  ? D ALA 69  
295 1 Y 1 D ILE 70  ? D ILE 70  
296 1 Y 1 D LEU 71  ? D LEU 71  
297 1 Y 1 E ASP 1   ? E ASP 1   
298 1 Y 1 E TRP 36  ? E TRP 36  
299 1 Y 1 E SER 119 A E SER 120 
300 1 Y 1 E SER 119 B E SER 121 
301 1 Y 1 E GLY 119 C E GLY 122 
302 1 Y 1 E GLY 119 D E GLY 123 
303 1 Y 1 E GLY 119 E E GLY 124 
304 1 Y 1 E GLY 119 F E GLY 125 
305 1 Y 1 E SER 119 G E SER 126 
306 1 Y 1 E GLY 119 H E GLY 127 
307 1 Y 1 E GLY 119 I E GLY 128 
308 1 Y 1 E GLY 119 J E GLY 129 
309 1 Y 1 E GLY 119 K E GLY 130 
310 1 Y 1 E SER 119 L E SER 131 
311 1 Y 1 E GLY 119 M E GLY 132 
312 1 Y 1 E GLY 119 N E GLY 133 
313 1 Y 1 E GLY 119 O E GLY 134 
314 1 Y 1 E GLY 119 P E GLY 135 
315 1 Y 1 E SER 119 Q E SER 136 
316 1 Y 1 E LYS 236 ? E LYS 248 
317 1 Y 1 E ALA 237 ? E ALA 249 
318 1 Y 1 E ALA 238 ? E ALA 250 
319 1 Y 1 E ALA 239 ? E ALA 251 
320 1 Y 1 E LEU 240 ? E LEU 252 
321 1 Y 1 E GLU 241 ? E GLU 253 
322 1 Y 1 E VAL 242 ? E VAL 254 
323 1 Y 1 E LEU 243 ? E LEU 255 
324 1 Y 1 E PHE 244 ? E PHE 256 
325 1 Y 1 E GLN 245 ? E GLN 257 
326 1 Y 1 E GLY 246 ? E GLY 258 
327 1 Y 1 E PRO 247 ? E PRO 259 
328 1 Y 1 E HIS 248 ? E HIS 260 
329 1 Y 1 E HIS 249 ? E HIS 261 
330 1 Y 1 E HIS 250 ? E HIS 262 
331 1 Y 1 E HIS 251 ? E HIS 263 
332 1 Y 1 E HIS 252 ? E HIS 264 
333 1 Y 1 E HIS 253 ? E HIS 265 
334 1 Y 1 E HIS 254 ? E HIS 266 
335 1 Y 1 E HIS 255 ? E HIS 267 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
7LD N1   N Y N 1   
7LD N3   N N N 2   
7LD C4   C Y N 3   
7LD C5   C Y N 4   
7LD C6   C Y N 5   
7LD C7   C Y N 6   
7LD C8   C Y N 7   
7LD C10  C N N 8   
7LD C13  C N N 9   
7LD C15  C N N 10  
7LD C17  C N N 11  
7LD C20  C N N 12  
7LD N2   N N N 13  
7LD C12  C N N 14  
7LD C11  C N R 15  
7LD C3   C Y N 16  
7LD C1   C Y N 17  
7LD C2   C Y N 18  
7LD C9   C N N 19  
7LD C14  C N R 20  
7LD C16  C N N 21  
7LD O1   O N N 22  
7LD C19  C N N 23  
7LD C18  C N N 24  
7LD H1   H N N 25  
7LD H2   H N N 26  
7LD H3   H N N 27  
7LD H4   H N N 28  
7LD H5   H N N 29  
7LD H6   H N N 30  
7LD H7   H N N 31  
7LD H8   H N N 32  
7LD H9   H N N 33  
7LD H10  H N N 34  
7LD H11  H N N 35  
7LD H12  H N N 36  
7LD H13  H N N 37  
7LD H14  H N N 38  
7LD H16  H N N 39  
7LD H17  H N N 40  
7LD H18  H N N 41  
7LD H19  H N N 42  
7LD H20  H N N 43  
7LD H21  H N N 44  
7LD H22  H N N 45  
7LD H23  H N N 46  
7LD H24  H N N 47  
7LD H25  H N N 48  
7LD H26  H N N 49  
ALA N    N N N 50  
ALA CA   C N S 51  
ALA C    C N N 52  
ALA O    O N N 53  
ALA CB   C N N 54  
ALA OXT  O N N 55  
ALA H    H N N 56  
ALA H2   H N N 57  
ALA HA   H N N 58  
ALA HB1  H N N 59  
ALA HB2  H N N 60  
ALA HB3  H N N 61  
ALA HXT  H N N 62  
ARG N    N N N 63  
ARG CA   C N S 64  
ARG C    C N N 65  
ARG O    O N N 66  
ARG CB   C N N 67  
ARG CG   C N N 68  
ARG CD   C N N 69  
ARG NE   N N N 70  
ARG CZ   C N N 71  
ARG NH1  N N N 72  
ARG NH2  N N N 73  
ARG OXT  O N N 74  
ARG H    H N N 75  
ARG H2   H N N 76  
ARG HA   H N N 77  
ARG HB2  H N N 78  
ARG HB3  H N N 79  
ARG HG2  H N N 80  
ARG HG3  H N N 81  
ARG HD2  H N N 82  
ARG HD3  H N N 83  
ARG HE   H N N 84  
ARG HH11 H N N 85  
ARG HH12 H N N 86  
ARG HH21 H N N 87  
ARG HH22 H N N 88  
ARG HXT  H N N 89  
ASN N    N N N 90  
ASN CA   C N S 91  
ASN C    C N N 92  
ASN O    O N N 93  
ASN CB   C N N 94  
ASN CG   C N N 95  
ASN OD1  O N N 96  
ASN ND2  N N N 97  
ASN OXT  O N N 98  
ASN H    H N N 99  
ASN H2   H N N 100 
ASN HA   H N N 101 
ASN HB2  H N N 102 
ASN HB3  H N N 103 
ASN HD21 H N N 104 
ASN HD22 H N N 105 
ASN HXT  H N N 106 
ASP N    N N N 107 
ASP CA   C N S 108 
ASP C    C N N 109 
ASP O    O N N 110 
ASP CB   C N N 111 
ASP CG   C N N 112 
ASP OD1  O N N 113 
ASP OD2  O N N 114 
ASP OXT  O N N 115 
ASP H    H N N 116 
ASP H2   H N N 117 
ASP HA   H N N 118 
ASP HB2  H N N 119 
ASP HB3  H N N 120 
ASP HD2  H N N 121 
ASP HXT  H N N 122 
CYS N    N N N 123 
CYS CA   C N R 124 
CYS C    C N N 125 
CYS O    O N N 126 
CYS CB   C N N 127 
CYS SG   S N N 128 
CYS OXT  O N N 129 
CYS H    H N N 130 
CYS H2   H N N 131 
CYS HA   H N N 132 
CYS HB2  H N N 133 
CYS HB3  H N N 134 
CYS HG   H N N 135 
CYS HXT  H N N 136 
GLN N    N N N 137 
GLN CA   C N S 138 
GLN C    C N N 139 
GLN O    O N N 140 
GLN CB   C N N 141 
GLN CG   C N N 142 
GLN CD   C N N 143 
GLN OE1  O N N 144 
GLN NE2  N N N 145 
GLN OXT  O N N 146 
GLN H    H N N 147 
GLN H2   H N N 148 
GLN HA   H N N 149 
GLN HB2  H N N 150 
GLN HB3  H N N 151 
GLN HG2  H N N 152 
GLN HG3  H N N 153 
GLN HE21 H N N 154 
GLN HE22 H N N 155 
GLN HXT  H N N 156 
GLU N    N N N 157 
GLU CA   C N S 158 
GLU C    C N N 159 
GLU O    O N N 160 
GLU CB   C N N 161 
GLU CG   C N N 162 
GLU CD   C N N 163 
GLU OE1  O N N 164 
GLU OE2  O N N 165 
GLU OXT  O N N 166 
GLU H    H N N 167 
GLU H2   H N N 168 
GLU HA   H N N 169 
GLU HB2  H N N 170 
GLU HB3  H N N 171 
GLU HG2  H N N 172 
GLU HG3  H N N 173 
GLU HE2  H N N 174 
GLU HXT  H N N 175 
GLY N    N N N 176 
GLY CA   C N N 177 
GLY C    C N N 178 
GLY O    O N N 179 
GLY OXT  O N N 180 
GLY H    H N N 181 
GLY H2   H N N 182 
GLY HA2  H N N 183 
GLY HA3  H N N 184 
GLY HXT  H N N 185 
HIS N    N N N 186 
HIS CA   C N S 187 
HIS C    C N N 188 
HIS O    O N N 189 
HIS CB   C N N 190 
HIS CG   C Y N 191 
HIS ND1  N Y N 192 
HIS CD2  C Y N 193 
HIS CE1  C Y N 194 
HIS NE2  N Y N 195 
HIS OXT  O N N 196 
HIS H    H N N 197 
HIS H2   H N N 198 
HIS HA   H N N 199 
HIS HB2  H N N 200 
HIS HB3  H N N 201 
HIS HD1  H N N 202 
HIS HD2  H N N 203 
HIS HE1  H N N 204 
HIS HE2  H N N 205 
HIS HXT  H N N 206 
ILE N    N N N 207 
ILE CA   C N S 208 
ILE C    C N N 209 
ILE O    O N N 210 
ILE CB   C N S 211 
ILE CG1  C N N 212 
ILE CG2  C N N 213 
ILE CD1  C N N 214 
ILE OXT  O N N 215 
ILE H    H N N 216 
ILE H2   H N N 217 
ILE HA   H N N 218 
ILE HB   H N N 219 
ILE HG12 H N N 220 
ILE HG13 H N N 221 
ILE HG21 H N N 222 
ILE HG22 H N N 223 
ILE HG23 H N N 224 
ILE HD11 H N N 225 
ILE HD12 H N N 226 
ILE HD13 H N N 227 
ILE HXT  H N N 228 
LEU N    N N N 229 
LEU CA   C N S 230 
LEU C    C N N 231 
LEU O    O N N 232 
LEU CB   C N N 233 
LEU CG   C N N 234 
LEU CD1  C N N 235 
LEU CD2  C N N 236 
LEU OXT  O N N 237 
LEU H    H N N 238 
LEU H2   H N N 239 
LEU HA   H N N 240 
LEU HB2  H N N 241 
LEU HB3  H N N 242 
LEU HG   H N N 243 
LEU HD11 H N N 244 
LEU HD12 H N N 245 
LEU HD13 H N N 246 
LEU HD21 H N N 247 
LEU HD22 H N N 248 
LEU HD23 H N N 249 
LEU HXT  H N N 250 
LYS N    N N N 251 
LYS CA   C N S 252 
LYS C    C N N 253 
LYS O    O N N 254 
LYS CB   C N N 255 
LYS CG   C N N 256 
LYS CD   C N N 257 
LYS CE   C N N 258 
LYS NZ   N N N 259 
LYS OXT  O N N 260 
LYS H    H N N 261 
LYS H2   H N N 262 
LYS HA   H N N 263 
LYS HB2  H N N 264 
LYS HB3  H N N 265 
LYS HG2  H N N 266 
LYS HG3  H N N 267 
LYS HD2  H N N 268 
LYS HD3  H N N 269 
LYS HE2  H N N 270 
LYS HE3  H N N 271 
LYS HZ1  H N N 272 
LYS HZ2  H N N 273 
LYS HZ3  H N N 274 
LYS HXT  H N N 275 
MET N    N N N 276 
MET CA   C N S 277 
MET C    C N N 278 
MET O    O N N 279 
MET CB   C N N 280 
MET CG   C N N 281 
MET SD   S N N 282 
MET CE   C N N 283 
MET OXT  O N N 284 
MET H    H N N 285 
MET H2   H N N 286 
MET HA   H N N 287 
MET HB2  H N N 288 
MET HB3  H N N 289 
MET HG2  H N N 290 
MET HG3  H N N 291 
MET HE1  H N N 292 
MET HE2  H N N 293 
MET HE3  H N N 294 
MET HXT  H N N 295 
PHE N    N N N 296 
PHE CA   C N S 297 
PHE C    C N N 298 
PHE O    O N N 299 
PHE CB   C N N 300 
PHE CG   C Y N 301 
PHE CD1  C Y N 302 
PHE CD2  C Y N 303 
PHE CE1  C Y N 304 
PHE CE2  C Y N 305 
PHE CZ   C Y N 306 
PHE OXT  O N N 307 
PHE H    H N N 308 
PHE H2   H N N 309 
PHE HA   H N N 310 
PHE HB2  H N N 311 
PHE HB3  H N N 312 
PHE HD1  H N N 313 
PHE HD2  H N N 314 
PHE HE1  H N N 315 
PHE HE2  H N N 316 
PHE HZ   H N N 317 
PHE HXT  H N N 318 
PRO N    N N N 319 
PRO CA   C N S 320 
PRO C    C N N 321 
PRO O    O N N 322 
PRO CB   C N N 323 
PRO CG   C N N 324 
PRO CD   C N N 325 
PRO OXT  O N N 326 
PRO H    H N N 327 
PRO HA   H N N 328 
PRO HB2  H N N 329 
PRO HB3  H N N 330 
PRO HG2  H N N 331 
PRO HG3  H N N 332 
PRO HD2  H N N 333 
PRO HD3  H N N 334 
PRO HXT  H N N 335 
SER N    N N N 336 
SER CA   C N S 337 
SER C    C N N 338 
SER O    O N N 339 
SER CB   C N N 340 
SER OG   O N N 341 
SER OXT  O N N 342 
SER H    H N N 343 
SER H2   H N N 344 
SER HA   H N N 345 
SER HB2  H N N 346 
SER HB3  H N N 347 
SER HG   H N N 348 
SER HXT  H N N 349 
THR N    N N N 350 
THR CA   C N S 351 
THR C    C N N 352 
THR O    O N N 353 
THR CB   C N R 354 
THR OG1  O N N 355 
THR CG2  C N N 356 
THR OXT  O N N 357 
THR H    H N N 358 
THR H2   H N N 359 
THR HA   H N N 360 
THR HB   H N N 361 
THR HG1  H N N 362 
THR HG21 H N N 363 
THR HG22 H N N 364 
THR HG23 H N N 365 
THR HXT  H N N 366 
TRP N    N N N 367 
TRP CA   C N S 368 
TRP C    C N N 369 
TRP O    O N N 370 
TRP CB   C N N 371 
TRP CG   C Y N 372 
TRP CD1  C Y N 373 
TRP CD2  C Y N 374 
TRP NE1  N Y N 375 
TRP CE2  C Y N 376 
TRP CE3  C Y N 377 
TRP CZ2  C Y N 378 
TRP CZ3  C Y N 379 
TRP CH2  C Y N 380 
TRP OXT  O N N 381 
TRP H    H N N 382 
TRP H2   H N N 383 
TRP HA   H N N 384 
TRP HB2  H N N 385 
TRP HB3  H N N 386 
TRP HD1  H N N 387 
TRP HE1  H N N 388 
TRP HE3  H N N 389 
TRP HZ2  H N N 390 
TRP HZ3  H N N 391 
TRP HH2  H N N 392 
TRP HXT  H N N 393 
TYR N    N N N 394 
TYR CA   C N S 395 
TYR C    C N N 396 
TYR O    O N N 397 
TYR CB   C N N 398 
TYR CG   C Y N 399 
TYR CD1  C Y N 400 
TYR CD2  C Y N 401 
TYR CE1  C Y N 402 
TYR CE2  C Y N 403 
TYR CZ   C Y N 404 
TYR OH   O N N 405 
TYR OXT  O N N 406 
TYR H    H N N 407 
TYR H2   H N N 408 
TYR HA   H N N 409 
TYR HB2  H N N 410 
TYR HB3  H N N 411 
TYR HD1  H N N 412 
TYR HD2  H N N 413 
TYR HE1  H N N 414 
TYR HE2  H N N 415 
TYR HH   H N N 416 
TYR HXT  H N N 417 
VAL N    N N N 418 
VAL CA   C N S 419 
VAL C    C N N 420 
VAL O    O N N 421 
VAL CB   C N N 422 
VAL CG1  C N N 423 
VAL CG2  C N N 424 
VAL OXT  O N N 425 
VAL H    H N N 426 
VAL H2   H N N 427 
VAL HA   H N N 428 
VAL HB   H N N 429 
VAL HG11 H N N 430 
VAL HG12 H N N 431 
VAL HG13 H N N 432 
VAL HG21 H N N 433 
VAL HG22 H N N 434 
VAL HG23 H N N 435 
VAL HXT  H N N 436 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
7LD C12 N2   sing N N 1   
7LD C8  C7   doub Y N 2   
7LD C8  N1   sing Y N 3   
7LD C15 C7   sing N N 4   
7LD C15 C11  sing N N 5   
7LD C7  C3   sing Y N 6   
7LD N1  C1   sing Y N 7   
7LD N2  C11  sing N N 8   
7LD N2  C13  sing N N 9   
7LD C11 C9   sing N N 10  
7LD C3  C1   doub Y N 11  
7LD C3  C6   sing Y N 12  
7LD C13 C14  sing N N 13  
7LD C1  C4   sing Y N 14  
7LD C9  C6   sing N N 15  
7LD C9  C10  doub N N 16  
7LD C6  C2   doub Y N 17  
7LD C4  C5   doub Y N 18  
7LD C14 C10  sing N N 19  
7LD C14 C16  sing N N 20  
7LD C17 N3   sing N N 21  
7LD C17 C18  sing N N 22  
7LD C2  C5   sing Y N 23  
7LD C16 N3   sing N N 24  
7LD C16 O1   doub N N 25  
7LD N3  C19  sing N N 26  
7LD C20 C19  sing N N 27  
7LD N1  H1   sing N N 28  
7LD C4  H2   sing N N 29  
7LD C5  H3   sing N N 30  
7LD C8  H4   sing N N 31  
7LD C10 H5   sing N N 32  
7LD C13 H6   sing N N 33  
7LD C13 H7   sing N N 34  
7LD C15 H8   sing N N 35  
7LD C15 H9   sing N N 36  
7LD C17 H10  sing N N 37  
7LD C17 H11  sing N N 38  
7LD C20 H12  sing N N 39  
7LD C20 H13  sing N N 40  
7LD C20 H14  sing N N 41  
7LD C12 H16  sing N N 42  
7LD C12 H17  sing N N 43  
7LD C12 H18  sing N N 44  
7LD C11 H19  sing N N 45  
7LD C2  H20  sing N N 46  
7LD C14 H21  sing N N 47  
7LD C19 H22  sing N N 48  
7LD C19 H23  sing N N 49  
7LD C18 H24  sing N N 50  
7LD C18 H25  sing N N 51  
7LD C18 H26  sing N N 52  
ALA N   CA   sing N N 53  
ALA N   H    sing N N 54  
ALA N   H2   sing N N 55  
ALA CA  C    sing N N 56  
ALA CA  CB   sing N N 57  
ALA CA  HA   sing N N 58  
ALA C   O    doub N N 59  
ALA C   OXT  sing N N 60  
ALA CB  HB1  sing N N 61  
ALA CB  HB2  sing N N 62  
ALA CB  HB3  sing N N 63  
ALA OXT HXT  sing N N 64  
ARG N   CA   sing N N 65  
ARG N   H    sing N N 66  
ARG N   H2   sing N N 67  
ARG CA  C    sing N N 68  
ARG CA  CB   sing N N 69  
ARG CA  HA   sing N N 70  
ARG C   O    doub N N 71  
ARG C   OXT  sing N N 72  
ARG CB  CG   sing N N 73  
ARG CB  HB2  sing N N 74  
ARG CB  HB3  sing N N 75  
ARG CG  CD   sing N N 76  
ARG CG  HG2  sing N N 77  
ARG CG  HG3  sing N N 78  
ARG CD  NE   sing N N 79  
ARG CD  HD2  sing N N 80  
ARG CD  HD3  sing N N 81  
ARG NE  CZ   sing N N 82  
ARG NE  HE   sing N N 83  
ARG CZ  NH1  sing N N 84  
ARG CZ  NH2  doub N N 85  
ARG NH1 HH11 sing N N 86  
ARG NH1 HH12 sing N N 87  
ARG NH2 HH21 sing N N 88  
ARG NH2 HH22 sing N N 89  
ARG OXT HXT  sing N N 90  
ASN N   CA   sing N N 91  
ASN N   H    sing N N 92  
ASN N   H2   sing N N 93  
ASN CA  C    sing N N 94  
ASN CA  CB   sing N N 95  
ASN CA  HA   sing N N 96  
ASN C   O    doub N N 97  
ASN C   OXT  sing N N 98  
ASN CB  CG   sing N N 99  
ASN CB  HB2  sing N N 100 
ASN CB  HB3  sing N N 101 
ASN CG  OD1  doub N N 102 
ASN CG  ND2  sing N N 103 
ASN ND2 HD21 sing N N 104 
ASN ND2 HD22 sing N N 105 
ASN OXT HXT  sing N N 106 
ASP N   CA   sing N N 107 
ASP N   H    sing N N 108 
ASP N   H2   sing N N 109 
ASP CA  C    sing N N 110 
ASP CA  CB   sing N N 111 
ASP CA  HA   sing N N 112 
ASP C   O    doub N N 113 
ASP C   OXT  sing N N 114 
ASP CB  CG   sing N N 115 
ASP CB  HB2  sing N N 116 
ASP CB  HB3  sing N N 117 
ASP CG  OD1  doub N N 118 
ASP CG  OD2  sing N N 119 
ASP OD2 HD2  sing N N 120 
ASP OXT HXT  sing N N 121 
CYS N   CA   sing N N 122 
CYS N   H    sing N N 123 
CYS N   H2   sing N N 124 
CYS CA  C    sing N N 125 
CYS CA  CB   sing N N 126 
CYS CA  HA   sing N N 127 
CYS C   O    doub N N 128 
CYS C   OXT  sing N N 129 
CYS CB  SG   sing N N 130 
CYS CB  HB2  sing N N 131 
CYS CB  HB3  sing N N 132 
CYS SG  HG   sing N N 133 
CYS OXT HXT  sing N N 134 
GLN N   CA   sing N N 135 
GLN N   H    sing N N 136 
GLN N   H2   sing N N 137 
GLN CA  C    sing N N 138 
GLN CA  CB   sing N N 139 
GLN CA  HA   sing N N 140 
GLN C   O    doub N N 141 
GLN C   OXT  sing N N 142 
GLN CB  CG   sing N N 143 
GLN CB  HB2  sing N N 144 
GLN CB  HB3  sing N N 145 
GLN CG  CD   sing N N 146 
GLN CG  HG2  sing N N 147 
GLN CG  HG3  sing N N 148 
GLN CD  OE1  doub N N 149 
GLN CD  NE2  sing N N 150 
GLN NE2 HE21 sing N N 151 
GLN NE2 HE22 sing N N 152 
GLN OXT HXT  sing N N 153 
GLU N   CA   sing N N 154 
GLU N   H    sing N N 155 
GLU N   H2   sing N N 156 
GLU CA  C    sing N N 157 
GLU CA  CB   sing N N 158 
GLU CA  HA   sing N N 159 
GLU C   O    doub N N 160 
GLU C   OXT  sing N N 161 
GLU CB  CG   sing N N 162 
GLU CB  HB2  sing N N 163 
GLU CB  HB3  sing N N 164 
GLU CG  CD   sing N N 165 
GLU CG  HG2  sing N N 166 
GLU CG  HG3  sing N N 167 
GLU CD  OE1  doub N N 168 
GLU CD  OE2  sing N N 169 
GLU OE2 HE2  sing N N 170 
GLU OXT HXT  sing N N 171 
GLY N   CA   sing N N 172 
GLY N   H    sing N N 173 
GLY N   H2   sing N N 174 
GLY CA  C    sing N N 175 
GLY CA  HA2  sing N N 176 
GLY CA  HA3  sing N N 177 
GLY C   O    doub N N 178 
GLY C   OXT  sing N N 179 
GLY OXT HXT  sing N N 180 
HIS N   CA   sing N N 181 
HIS N   H    sing N N 182 
HIS N   H2   sing N N 183 
HIS CA  C    sing N N 184 
HIS CA  CB   sing N N 185 
HIS CA  HA   sing N N 186 
HIS C   O    doub N N 187 
HIS C   OXT  sing N N 188 
HIS CB  CG   sing N N 189 
HIS CB  HB2  sing N N 190 
HIS CB  HB3  sing N N 191 
HIS CG  ND1  sing Y N 192 
HIS CG  CD2  doub Y N 193 
HIS ND1 CE1  doub Y N 194 
HIS ND1 HD1  sing N N 195 
HIS CD2 NE2  sing Y N 196 
HIS CD2 HD2  sing N N 197 
HIS CE1 NE2  sing Y N 198 
HIS CE1 HE1  sing N N 199 
HIS NE2 HE2  sing N N 200 
HIS OXT HXT  sing N N 201 
ILE N   CA   sing N N 202 
ILE N   H    sing N N 203 
ILE N   H2   sing N N 204 
ILE CA  C    sing N N 205 
ILE CA  CB   sing N N 206 
ILE CA  HA   sing N N 207 
ILE C   O    doub N N 208 
ILE C   OXT  sing N N 209 
ILE CB  CG1  sing N N 210 
ILE CB  CG2  sing N N 211 
ILE CB  HB   sing N N 212 
ILE CG1 CD1  sing N N 213 
ILE CG1 HG12 sing N N 214 
ILE CG1 HG13 sing N N 215 
ILE CG2 HG21 sing N N 216 
ILE CG2 HG22 sing N N 217 
ILE CG2 HG23 sing N N 218 
ILE CD1 HD11 sing N N 219 
ILE CD1 HD12 sing N N 220 
ILE CD1 HD13 sing N N 221 
ILE OXT HXT  sing N N 222 
LEU N   CA   sing N N 223 
LEU N   H    sing N N 224 
LEU N   H2   sing N N 225 
LEU CA  C    sing N N 226 
LEU CA  CB   sing N N 227 
LEU CA  HA   sing N N 228 
LEU C   O    doub N N 229 
LEU C   OXT  sing N N 230 
LEU CB  CG   sing N N 231 
LEU CB  HB2  sing N N 232 
LEU CB  HB3  sing N N 233 
LEU CG  CD1  sing N N 234 
LEU CG  CD2  sing N N 235 
LEU CG  HG   sing N N 236 
LEU CD1 HD11 sing N N 237 
LEU CD1 HD12 sing N N 238 
LEU CD1 HD13 sing N N 239 
LEU CD2 HD21 sing N N 240 
LEU CD2 HD22 sing N N 241 
LEU CD2 HD23 sing N N 242 
LEU OXT HXT  sing N N 243 
LYS N   CA   sing N N 244 
LYS N   H    sing N N 245 
LYS N   H2   sing N N 246 
LYS CA  C    sing N N 247 
LYS CA  CB   sing N N 248 
LYS CA  HA   sing N N 249 
LYS C   O    doub N N 250 
LYS C   OXT  sing N N 251 
LYS CB  CG   sing N N 252 
LYS CB  HB2  sing N N 253 
LYS CB  HB3  sing N N 254 
LYS CG  CD   sing N N 255 
LYS CG  HG2  sing N N 256 
LYS CG  HG3  sing N N 257 
LYS CD  CE   sing N N 258 
LYS CD  HD2  sing N N 259 
LYS CD  HD3  sing N N 260 
LYS CE  NZ   sing N N 261 
LYS CE  HE2  sing N N 262 
LYS CE  HE3  sing N N 263 
LYS NZ  HZ1  sing N N 264 
LYS NZ  HZ2  sing N N 265 
LYS NZ  HZ3  sing N N 266 
LYS OXT HXT  sing N N 267 
MET N   CA   sing N N 268 
MET N   H    sing N N 269 
MET N   H2   sing N N 270 
MET CA  C    sing N N 271 
MET CA  CB   sing N N 272 
MET CA  HA   sing N N 273 
MET C   O    doub N N 274 
MET C   OXT  sing N N 275 
MET CB  CG   sing N N 276 
MET CB  HB2  sing N N 277 
MET CB  HB3  sing N N 278 
MET CG  SD   sing N N 279 
MET CG  HG2  sing N N 280 
MET CG  HG3  sing N N 281 
MET SD  CE   sing N N 282 
MET CE  HE1  sing N N 283 
MET CE  HE2  sing N N 284 
MET CE  HE3  sing N N 285 
MET OXT HXT  sing N N 286 
PHE N   CA   sing N N 287 
PHE N   H    sing N N 288 
PHE N   H2   sing N N 289 
PHE CA  C    sing N N 290 
PHE CA  CB   sing N N 291 
PHE CA  HA   sing N N 292 
PHE C   O    doub N N 293 
PHE C   OXT  sing N N 294 
PHE CB  CG   sing N N 295 
PHE CB  HB2  sing N N 296 
PHE CB  HB3  sing N N 297 
PHE CG  CD1  doub Y N 298 
PHE CG  CD2  sing Y N 299 
PHE CD1 CE1  sing Y N 300 
PHE CD1 HD1  sing N N 301 
PHE CD2 CE2  doub Y N 302 
PHE CD2 HD2  sing N N 303 
PHE CE1 CZ   doub Y N 304 
PHE CE1 HE1  sing N N 305 
PHE CE2 CZ   sing Y N 306 
PHE CE2 HE2  sing N N 307 
PHE CZ  HZ   sing N N 308 
PHE OXT HXT  sing N N 309 
PRO N   CA   sing N N 310 
PRO N   CD   sing N N 311 
PRO N   H    sing N N 312 
PRO CA  C    sing N N 313 
PRO CA  CB   sing N N 314 
PRO CA  HA   sing N N 315 
PRO C   O    doub N N 316 
PRO C   OXT  sing N N 317 
PRO CB  CG   sing N N 318 
PRO CB  HB2  sing N N 319 
PRO CB  HB3  sing N N 320 
PRO CG  CD   sing N N 321 
PRO CG  HG2  sing N N 322 
PRO CG  HG3  sing N N 323 
PRO CD  HD2  sing N N 324 
PRO CD  HD3  sing N N 325 
PRO OXT HXT  sing N N 326 
SER N   CA   sing N N 327 
SER N   H    sing N N 328 
SER N   H2   sing N N 329 
SER CA  C    sing N N 330 
SER CA  CB   sing N N 331 
SER CA  HA   sing N N 332 
SER C   O    doub N N 333 
SER C   OXT  sing N N 334 
SER CB  OG   sing N N 335 
SER CB  HB2  sing N N 336 
SER CB  HB3  sing N N 337 
SER OG  HG   sing N N 338 
SER OXT HXT  sing N N 339 
THR N   CA   sing N N 340 
THR N   H    sing N N 341 
THR N   H2   sing N N 342 
THR CA  C    sing N N 343 
THR CA  CB   sing N N 344 
THR CA  HA   sing N N 345 
THR C   O    doub N N 346 
THR C   OXT  sing N N 347 
THR CB  OG1  sing N N 348 
THR CB  CG2  sing N N 349 
THR CB  HB   sing N N 350 
THR OG1 HG1  sing N N 351 
THR CG2 HG21 sing N N 352 
THR CG2 HG22 sing N N 353 
THR CG2 HG23 sing N N 354 
THR OXT HXT  sing N N 355 
TRP N   CA   sing N N 356 
TRP N   H    sing N N 357 
TRP N   H2   sing N N 358 
TRP CA  C    sing N N 359 
TRP CA  CB   sing N N 360 
TRP CA  HA   sing N N 361 
TRP C   O    doub N N 362 
TRP C   OXT  sing N N 363 
TRP CB  CG   sing N N 364 
TRP CB  HB2  sing N N 365 
TRP CB  HB3  sing N N 366 
TRP CG  CD1  doub Y N 367 
TRP CG  CD2  sing Y N 368 
TRP CD1 NE1  sing Y N 369 
TRP CD1 HD1  sing N N 370 
TRP CD2 CE2  doub Y N 371 
TRP CD2 CE3  sing Y N 372 
TRP NE1 CE2  sing Y N 373 
TRP NE1 HE1  sing N N 374 
TRP CE2 CZ2  sing Y N 375 
TRP CE3 CZ3  doub Y N 376 
TRP CE3 HE3  sing N N 377 
TRP CZ2 CH2  doub Y N 378 
TRP CZ2 HZ2  sing N N 379 
TRP CZ3 CH2  sing Y N 380 
TRP CZ3 HZ3  sing N N 381 
TRP CH2 HH2  sing N N 382 
TRP OXT HXT  sing N N 383 
TYR N   CA   sing N N 384 
TYR N   H    sing N N 385 
TYR N   H2   sing N N 386 
TYR CA  C    sing N N 387 
TYR CA  CB   sing N N 388 
TYR CA  HA   sing N N 389 
TYR C   O    doub N N 390 
TYR C   OXT  sing N N 391 
TYR CB  CG   sing N N 392 
TYR CB  HB2  sing N N 393 
TYR CB  HB3  sing N N 394 
TYR CG  CD1  doub Y N 395 
TYR CG  CD2  sing Y N 396 
TYR CD1 CE1  sing Y N 397 
TYR CD1 HD1  sing N N 398 
TYR CD2 CE2  doub Y N 399 
TYR CD2 HD2  sing N N 400 
TYR CE1 CZ   doub Y N 401 
TYR CE1 HE1  sing N N 402 
TYR CE2 CZ   sing Y N 403 
TYR CE2 HE2  sing N N 404 
TYR CZ  OH   sing N N 405 
TYR OH  HH   sing N N 406 
TYR OXT HXT  sing N N 407 
VAL N   CA   sing N N 408 
VAL N   H    sing N N 409 
VAL N   H2   sing N N 410 
VAL CA  C    sing N N 411 
VAL CA  CB   sing N N 412 
VAL CA  HA   sing N N 413 
VAL C   O    doub N N 414 
VAL C   OXT  sing N N 415 
VAL CB  CG1  sing N N 416 
VAL CB  CG2  sing N N 417 
VAL CB  HB   sing N N 418 
VAL CG1 HG11 sing N N 419 
VAL CG1 HG12 sing N N 420 
VAL CG1 HG13 sing N N 421 
VAL CG2 HG21 sing N N 422 
VAL CG2 HG22 sing N N 423 
VAL CG2 HG23 sing N N 424 
VAL OXT HXT  sing N N 425 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-02-24 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9AS4 
_em_admin.last_update        2025-04-02 
_em_admin.map_release_date   2025-04-02 
_em_admin.title              
;Global reconstruction of 5-HT2AR bound to LSD in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
;
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          7108 
_em_entity_assembly_recombinant.organism             'Spodoptera frugiperda' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         49.5 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Defense Advanced Research Projects Agency (DARPA)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           HR0011-20-2-0029 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9AS4 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . VAL A 1 84  ? 153.235 133.894 167.089 1.00 28.59 ? 84  VAL A N   1 
ATOM   2    C CA  . VAL A 1 84  ? 151.882 134.063 166.575 1.00 33.74 ? 84  VAL A CA  1 
ATOM   3    C C   . VAL A 1 84  ? 151.894 135.135 165.489 1.00 41.70 ? 84  VAL A C   1 
ATOM   4    O O   . VAL A 1 84  ? 151.144 135.054 164.519 1.00 42.94 ? 84  VAL A O   1 
ATOM   5    C CB  . VAL A 1 84  ? 150.894 134.414 167.712 1.00 34.06 ? 84  VAL A CB  1 
ATOM   6    C CG1 . VAL A 1 84  ? 149.614 135.037 167.172 1.00 28.16 ? 84  VAL A CG1 1 
ATOM   7    C CG2 . VAL A 1 84  ? 150.569 133.177 168.526 1.00 42.01 ? 84  VAL A CG2 1 
ATOM   8    N N   . ILE A 1 85  ? 152.745 136.149 165.664 1.00 45.36 ? 85  ILE A N   1 
ATOM   9    C CA  . ILE A 1 85  ? 152.877 137.186 164.645 1.00 33.87 ? 85  ILE A CA  1 
ATOM   10   C C   . ILE A 1 85  ? 153.492 136.609 163.379 1.00 40.72 ? 85  ILE A C   1 
ATOM   11   O O   . ILE A 1 85  ? 152.986 136.826 162.269 1.00 47.82 ? 85  ILE A O   1 
ATOM   12   C CB  . ILE A 1 85  ? 153.705 138.368 165.179 1.00 30.83 ? 85  ILE A CB  1 
ATOM   13   C CG1 . ILE A 1 85  ? 153.033 139.027 166.388 1.00 37.27 ? 85  ILE A CG1 1 
ATOM   14   C CG2 . ILE A 1 85  ? 153.918 139.392 164.079 1.00 37.21 ? 85  ILE A CG2 1 
ATOM   15   C CD1 . ILE A 1 85  ? 153.997 139.772 167.278 1.00 38.78 ? 85  ILE A CD1 1 
ATOM   16   N N   . ILE A 1 86  ? 154.592 135.867 163.522 1.00 45.49 ? 86  ILE A N   1 
ATOM   17   C CA  . ILE A 1 86  ? 155.225 135.247 162.363 1.00 43.49 ? 86  ILE A CA  1 
ATOM   18   C C   . ILE A 1 86  ? 154.272 134.254 161.717 1.00 43.86 ? 86  ILE A C   1 
ATOM   19   O O   . ILE A 1 86  ? 154.158 134.194 160.488 1.00 47.76 ? 86  ILE A O   1 
ATOM   20   C CB  . ILE A 1 86  ? 156.555 134.580 162.763 1.00 44.59 ? 86  ILE A CB  1 
ATOM   21   C CG1 . ILE A 1 86  ? 157.564 135.633 163.240 1.00 46.48 ? 86  ILE A CG1 1 
ATOM   22   C CG2 . ILE A 1 86  ? 157.113 133.776 161.588 1.00 43.81 ? 86  ILE A CG2 1 
ATOM   23   C CD1 . ILE A 1 86  ? 158.774 135.062 163.957 1.00 49.10 ? 86  ILE A CD1 1 
ATOM   24   N N   . LEU A 1 87  ? 153.572 133.461 162.531 1.00 35.75 ? 87  LEU A N   1 
ATOM   25   C CA  . LEU A 1 87  ? 152.597 132.524 161.984 1.00 29.74 ? 87  LEU A CA  1 
ATOM   26   C C   . LEU A 1 87  ? 151.487 133.244 161.234 1.00 36.00 ? 87  LEU A C   1 
ATOM   27   O O   . LEU A 1 87  ? 151.115 132.818 160.138 1.00 38.33 ? 87  LEU A O   1 
ATOM   28   C CB  . LEU A 1 87  ? 151.992 131.659 163.091 1.00 34.66 ? 87  LEU A CB  1 
ATOM   29   C CG  . LEU A 1 87  ? 152.392 130.186 163.057 1.00 36.48 ? 87  LEU A CG  1 
ATOM   30   C CD1 . LEU A 1 87  ? 153.853 130.016 163.439 1.00 41.07 ? 87  LEU A CD1 1 
ATOM   31   C CD2 . LEU A 1 87  ? 151.497 129.371 163.971 1.00 37.67 ? 87  LEU A CD2 1 
ATOM   32   N N   . THR A 1 88  ? 150.963 134.337 161.793 1.00 39.65 ? 88  THR A N   1 
ATOM   33   C CA  . THR A 1 88  ? 149.904 135.085 161.121 1.00 37.47 ? 88  THR A CA  1 
ATOM   34   C C   . THR A 1 88  ? 150.374 135.615 159.774 1.00 36.73 ? 88  THR A C   1 
ATOM   35   O O   . THR A 1 88  ? 149.719 135.399 158.743 1.00 42.21 ? 88  THR A O   1 
ATOM   36   C CB  . THR A 1 88  ? 149.444 136.241 162.007 1.00 34.95 ? 88  THR A CB  1 
ATOM   37   O OG1 . THR A 1 88  ? 148.853 135.725 163.204 1.00 40.39 ? 88  THR A OG1 1 
ATOM   38   C CG2 . THR A 1 88  ? 148.435 137.111 161.280 1.00 39.13 ? 88  THR A CG2 1 
ATOM   39   N N   . ILE A 1 89  ? 151.512 136.312 159.766 1.00 36.97 ? 89  ILE A N   1 
ATOM   40   C CA  . ILE A 1 89  ? 151.991 136.922 158.532 1.00 33.21 ? 89  ILE A CA  1 
ATOM   41   C C   . ILE A 1 89  ? 152.305 135.851 157.497 1.00 40.87 ? 89  ILE A C   1 
ATOM   42   O O   . ILE A 1 89  ? 151.884 135.955 156.341 1.00 47.68 ? 89  ILE A O   1 
ATOM   43   C CB  . ILE A 1 89  ? 153.210 137.823 158.807 1.00 42.82 ? 89  ILE A CB  1 
ATOM   44   C CG1 . ILE A 1 89  ? 152.849 138.987 159.739 1.00 46.66 ? 89  ILE A CG1 1 
ATOM   45   C CG2 . ILE A 1 89  ? 153.767 138.370 157.502 1.00 45.85 ? 89  ILE A CG2 1 
ATOM   46   C CD1 . ILE A 1 89  ? 154.030 139.535 160.512 1.00 43.17 ? 89  ILE A CD1 1 
ATOM   47   N N   . ALA A 1 90  ? 153.029 134.800 157.891 1.00 44.68 ? 90  ALA A N   1 
ATOM   48   C CA  . ALA A 1 90  ? 153.399 133.735 156.970 1.00 47.32 ? 90  ALA A CA  1 
ATOM   49   C C   . ALA A 1 90  ? 152.210 132.913 156.493 1.00 44.46 ? 90  ALA A C   1 
ATOM   50   O O   . ALA A 1 90  ? 152.283 132.332 155.407 1.00 45.95 ? 90  ALA A O   1 
ATOM   51   C CB  . ALA A 1 90  ? 154.420 132.806 157.628 1.00 44.55 ? 90  ALA A CB  1 
ATOM   52   N N   . GLY A 1 91  ? 151.133 132.832 157.268 1.00 39.94 ? 91  GLY A N   1 
ATOM   53   C CA  . GLY A 1 91  ? 149.961 132.107 156.837 1.00 37.89 ? 91  GLY A CA  1 
ATOM   54   C C   . GLY A 1 91  ? 149.136 132.897 155.850 1.00 35.76 ? 91  GLY A C   1 
ATOM   55   O O   . GLY A 1 91  ? 148.624 132.335 154.880 1.00 42.58 ? 91  GLY A O   1 
ATOM   56   N N   . ASN A 1 92  ? 148.986 134.199 156.084 1.00 39.07 ? 92  ASN A N   1 
ATOM   57   C CA  . ASN A 1 92  ? 148.200 135.023 155.174 1.00 40.77 ? 92  ASN A CA  1 
ATOM   58   C C   . ASN A 1 92  ? 148.926 135.376 153.882 1.00 40.85 ? 92  ASN A C   1 
ATOM   59   O O   . ASN A 1 92  ? 148.281 135.412 152.822 1.00 37.13 ? 92  ASN A O   1 
ATOM   60   C CB  . ASN A 1 92  ? 147.749 136.299 155.879 1.00 48.03 ? 92  ASN A CB  1 
ATOM   61   C CG  . ASN A 1 92  ? 146.756 136.019 156.981 1.00 43.04 ? 92  ASN A CG  1 
ATOM   62   O OD1 . ASN A 1 92  ? 145.548 136.113 156.779 1.00 43.32 ? 92  ASN A OD1 1 
ATOM   63   N ND2 . ASN A 1 92  ? 147.256 135.631 158.143 1.00 40.24 ? 92  ASN A ND2 1 
ATOM   64   N N   . ILE A 1 93  ? 150.241 135.630 153.917 1.00 44.71 ? 93  ILE A N   1 
ATOM   65   C CA  . ILE A 1 93  ? 150.939 135.921 152.668 1.00 46.37 ? 93  ILE A CA  1 
ATOM   66   C C   . ILE A 1 93  ? 151.090 134.687 151.794 1.00 48.12 ? 93  ILE A C   1 
ATOM   67   O O   . ILE A 1 93  ? 151.525 134.823 150.647 1.00 56.70 ? 93  ILE A O   1 
ATOM   68   C CB  . ILE A 1 93  ? 152.331 136.566 152.870 1.00 42.42 ? 93  ILE A CB  1 
ATOM   69   C CG1 . ILE A 1 93  ? 153.352 135.603 153.503 1.00 46.91 ? 93  ILE A CG1 1 
ATOM   70   C CG2 . ILE A 1 93  ? 152.202 137.870 153.660 1.00 39.37 ? 93  ILE A CG2 1 
ATOM   71   C CD1 . ILE A 1 93  ? 154.724 136.209 153.700 1.00 50.02 ? 93  ILE A CD1 1 
ATOM   72   N N   . LEU A 1 94  ? 150.786 133.491 152.299 1.00 36.56 ? 94  LEU A N   1 
ATOM   73   C CA  . LEU A 1 94  ? 150.735 132.292 151.473 1.00 38.59 ? 94  LEU A CA  1 
ATOM   74   C C   . LEU A 1 94  ? 149.361 132.060 150.863 1.00 49.79 ? 94  LEU A C   1 
ATOM   75   O O   . LEU A 1 94  ? 149.247 131.288 149.907 1.00 57.45 ? 94  LEU A O   1 
ATOM   76   C CB  . LEU A 1 94  ? 151.135 131.060 152.288 1.00 45.14 ? 94  LEU A CB  1 
ATOM   77   C CG  . LEU A 1 94  ? 152.636 130.776 152.399 1.00 45.59 ? 94  LEU A CG  1 
ATOM   78   C CD1 . LEU A 1 94  ? 152.912 129.761 153.496 1.00 46.56 ? 94  LEU A CD1 1 
ATOM   79   C CD2 . LEU A 1 94  ? 153.237 130.320 151.080 1.00 48.16 ? 94  LEU A CD2 1 
ATOM   80   N N   . VAL A 1 95  ? 148.322 132.698 151.392 1.00 52.35 ? 95  VAL A N   1 
ATOM   81   C CA  . VAL A 1 95  ? 146.977 132.628 150.833 1.00 48.03 ? 95  VAL A CA  1 
ATOM   82   C C   . VAL A 1 95  ? 146.748 133.738 149.822 1.00 49.92 ? 95  VAL A C   1 
ATOM   83   O O   . VAL A 1 95  ? 145.957 133.588 148.892 1.00 47.07 ? 95  VAL A O   1 
ATOM   84   C CB  . VAL A 1 95  ? 145.929 132.680 151.966 1.00 44.09 ? 95  VAL A CB  1 
ATOM   85   C CG1 . VAL A 1 95  ? 144.525 132.805 151.396 1.00 41.51 ? 95  VAL A CG1 1 
ATOM   86   C CG2 . VAL A 1 95  ? 146.043 131.450 152.839 1.00 42.15 ? 95  VAL A CG2 1 
ATOM   87   N N   . ILE A 1 96  ? 147.426 134.872 149.995 1.00 50.75 ? 96  ILE A N   1 
ATOM   88   C CA  . ILE A 1 96  ? 147.243 135.975 149.055 1.00 47.30 ? 96  ILE A CA  1 
ATOM   89   C C   . ILE A 1 96  ? 147.829 135.629 147.691 1.00 50.07 ? 96  ILE A C   1 
ATOM   90   O O   . ILE A 1 96  ? 147.251 135.974 146.654 1.00 61.19 ? 96  ILE A O   1 
ATOM   91   C CB  . ILE A 1 96  ? 147.834 137.278 149.626 1.00 46.52 ? 96  ILE A CB  1 
ATOM   92   C CG1 . ILE A 1 96  ? 147.040 137.706 150.868 1.00 49.66 ? 96  ILE A CG1 1 
ATOM   93   C CG2 . ILE A 1 96  ? 147.800 138.373 148.561 1.00 44.50 ? 96  ILE A CG2 1 
ATOM   94   C CD1 . ILE A 1 96  ? 147.686 138.787 151.700 1.00 46.48 ? 96  ILE A CD1 1 
ATOM   95   N N   . MET A 1 97  ? 148.980 134.948 147.656 1.00 41.13 ? 97  MET A N   1 
ATOM   96   C CA  . MET A 1 97  ? 149.549 134.598 146.355 1.00 47.12 ? 97  MET A CA  1 
ATOM   97   C C   . MET A 1 97  ? 148.764 133.495 145.664 1.00 52.83 ? 97  MET A C   1 
ATOM   98   O O   . MET A 1 97  ? 148.616 133.538 144.439 1.00 55.42 ? 97  MET A O   1 
ATOM   99   C CB  . MET A 1 97  ? 151.014 134.153 146.441 1.00 44.79 ? 97  MET A CB  1 
ATOM   100  C CG  . MET A 1 97  ? 151.831 134.731 147.554 1.00 47.52 ? 97  MET A CG  1 
ATOM   101  S SD  . MET A 1 97  ? 153.577 134.286 147.504 1.00 62.02 ? 97  MET A SD  1 
ATOM   102  C CE  . MET A 1 97  ? 153.508 132.508 147.693 1.00 47.68 ? 97  MET A CE  1 
ATOM   103  N N   . ALA A 1 98  ? 148.253 132.518 146.414 1.00 47.79 ? 98  ALA A N   1 
ATOM   104  C CA  . ALA A 1 98  ? 147.600 131.372 145.794 1.00 49.76 ? 98  ALA A CA  1 
ATOM   105  C C   . ALA A 1 98  ? 146.368 131.772 144.996 1.00 52.69 ? 98  ALA A C   1 
ATOM   106  O O   . ALA A 1 98  ? 145.985 131.053 144.068 1.00 57.71 ? 98  ALA A O   1 
ATOM   107  C CB  . ALA A 1 98  ? 147.228 130.338 146.853 1.00 48.29 ? 98  ALA A CB  1 
ATOM   108  N N   . VAL A 1 99  ? 145.744 132.898 145.328 1.00 49.55 ? 99  VAL A N   1 
ATOM   109  C CA  . VAL A 1 99  ? 144.634 133.429 144.543 1.00 51.23 ? 99  VAL A CA  1 
ATOM   110  C C   . VAL A 1 99  ? 145.171 134.360 143.466 1.00 51.95 ? 99  VAL A C   1 
ATOM   111  O O   . VAL A 1 99  ? 144.567 134.508 142.404 1.00 57.66 ? 99  VAL A O   1 
ATOM   112  C CB  . VAL A 1 99  ? 143.619 134.156 145.434 1.00 52.06 ? 99  VAL A CB  1 
ATOM   113  C CG1 . VAL A 1 99  ? 142.565 134.859 144.585 1.00 55.30 ? 99  VAL A CG1 1 
ATOM   114  C CG2 . VAL A 1 99  ? 142.971 133.173 146.384 1.00 49.35 ? 99  VAL A CG2 1 
ATOM   115  N N   . LEU A 1 105 ? 142.263 129.241 141.267 1.00 59.75 ? 105 LEU A N   1 
ATOM   116  C CA  . LEU A 1 105 ? 141.417 129.656 142.380 1.00 58.80 ? 105 LEU A CA  1 
ATOM   117  C C   . LEU A 1 105 ? 141.098 131.146 142.292 1.00 61.20 ? 105 LEU A C   1 
ATOM   118  O O   . LEU A 1 105 ? 141.579 131.944 143.095 1.00 62.77 ? 105 LEU A O   1 
ATOM   119  C CB  . LEU A 1 105 ? 142.092 129.340 143.716 1.00 54.55 ? 105 LEU A CB  1 
ATOM   120  C CG  . LEU A 1 105 ? 142.685 127.939 143.847 1.00 54.37 ? 105 LEU A CG  1 
ATOM   121  C CD1 . LEU A 1 105 ? 144.191 127.989 143.684 1.00 56.27 ? 105 LEU A CD1 1 
ATOM   122  C CD2 . LEU A 1 105 ? 142.311 127.338 145.180 1.00 56.35 ? 105 LEU A CD2 1 
ATOM   123  N N   . GLN A 1 106 ? 140.286 131.507 141.304 1.00 65.47 ? 106 GLN A N   1 
ATOM   124  C CA  . GLN A 1 106 ? 139.832 132.874 141.085 1.00 61.72 ? 106 GLN A CA  1 
ATOM   125  C C   . GLN A 1 106 ? 138.310 132.930 141.086 1.00 62.23 ? 106 GLN A C   1 
ATOM   126  O O   . GLN A 1 106 ? 137.693 133.694 140.342 1.00 61.74 ? 106 GLN A O   1 
ATOM   127  C CB  . GLN A 1 106 ? 140.399 133.427 139.779 1.00 63.70 ? 106 GLN A CB  1 
ATOM   128  C CG  . GLN A 1 106 ? 141.905 133.641 139.804 1.00 61.84 ? 106 GLN A CG  1 
ATOM   129  C CD  . GLN A 1 106 ? 142.339 134.820 138.958 1.00 63.93 ? 106 GLN A CD  1 
ATOM   130  O OE1 . GLN A 1 106 ? 142.566 135.914 139.470 1.00 60.37 ? 106 GLN A OE1 1 
ATOM   131  N NE2 . GLN A 1 106 ? 142.461 134.601 137.655 1.00 64.26 ? 106 GLN A NE2 1 
ATOM   132  N N   . ASN A 1 107 ? 137.721 132.111 141.963 1.00 68.03 ? 107 ASN A N   1 
ATOM   133  C CA  . ASN A 1 107 ? 136.239 132.020 142.039 1.00 69.04 ? 107 ASN A CA  1 
ATOM   134  C C   . ASN A 1 107 ? 135.659 133.222 142.781 1.00 68.53 ? 107 ASN A C   1 
ATOM   135  O O   . ASN A 1 107 ? 136.384 133.839 143.593 1.00 68.27 ? 107 ASN A O   1 
ATOM   136  C CB  . ASN A 1 107 ? 135.798 130.734 142.728 1.00 63.53 ? 107 ASN A CB  1 
ATOM   137  C CG  . ASN A 1 107 ? 135.244 129.729 141.749 1.00 67.43 ? 107 ASN A CG  1 
ATOM   138  O OD1 . ASN A 1 107 ? 134.836 130.098 140.642 1.00 68.94 ? 107 ASN A OD1 1 
ATOM   139  N ND2 . ASN A 1 107 ? 135.215 128.461 142.134 1.00 69.44 ? 107 ASN A ND2 1 
ATOM   140  N N   . ALA A 1 108 ? 134.388 133.523 142.518 1.00 57.07 ? 108 ALA A N   1 
ATOM   141  C CA  . ALA A 1 108 ? 133.714 134.627 143.187 1.00 58.68 ? 108 ALA A CA  1 
ATOM   142  C C   . ALA A 1 108 ? 133.654 134.448 144.696 1.00 62.21 ? 108 ALA A C   1 
ATOM   143  O O   . ALA A 1 108 ? 133.599 135.447 145.419 1.00 57.91 ? 108 ALA A O   1 
ATOM   144  C CB  . ALA A 1 108 ? 132.295 134.787 142.639 1.00 57.03 ? 108 ALA A CB  1 
ATOM   145  N N   . THR A 1 109 ? 133.664 133.207 145.184 1.00 58.91 ? 109 THR A N   1 
ATOM   146  C CA  . THR A 1 109 ? 133.685 132.923 146.612 1.00 54.49 ? 109 THR A CA  1 
ATOM   147  C C   . THR A 1 109 ? 135.092 132.850 147.180 1.00 51.00 ? 109 THR A C   1 
ATOM   148  O O   . THR A 1 109 ? 135.275 133.077 148.379 1.00 57.13 ? 109 THR A O   1 
ATOM   149  C CB  . THR A 1 109 ? 132.969 131.599 146.902 1.00 55.92 ? 109 THR A CB  1 
ATOM   150  O OG1 . THR A 1 109 ? 131.743 131.539 146.164 1.00 53.04 ? 109 THR A OG1 1 
ATOM   151  C CG2 . THR A 1 109 ? 132.672 131.457 148.385 1.00 58.97 ? 109 THR A CG2 1 
ATOM   152  N N   . ASN A 1 110 ? 136.085 132.527 146.354 1.00 49.16 ? 110 ASN A N   1 
ATOM   153  C CA  . ASN A 1 110 ? 137.458 132.477 146.835 1.00 56.11 ? 110 ASN A CA  1 
ATOM   154  C C   . ASN A 1 110 ? 138.063 133.867 146.972 1.00 53.59 ? 110 ASN A C   1 
ATOM   155  O O   . ASN A 1 110 ? 138.936 134.075 147.822 1.00 51.74 ? 110 ASN A O   1 
ATOM   156  C CB  . ASN A 1 110 ? 138.312 131.628 145.897 1.00 59.48 ? 110 ASN A CB  1 
ATOM   157  C CG  . ASN A 1 110 ? 139.589 131.153 146.551 1.00 59.15 ? 110 ASN A CG  1 
ATOM   158  O OD1 . ASN A 1 110 ? 139.864 129.957 146.601 1.00 54.62 ? 110 ASN A OD1 1 
ATOM   159  N ND2 . ASN A 1 110 ? 140.377 132.089 147.059 1.00 55.42 ? 110 ASN A ND2 1 
ATOM   160  N N   . TYR A 1 111 ? 137.631 134.824 146.149 1.00 57.24 ? 111 TYR A N   1 
ATOM   161  C CA  . TYR A 1 111 ? 138.133 136.186 146.287 1.00 61.63 ? 111 TYR A CA  1 
ATOM   162  C C   . TYR A 1 111 ? 137.720 136.795 147.618 1.00 56.54 ? 111 TYR A C   1 
ATOM   163  O O   . TYR A 1 111 ? 138.461 137.607 148.182 1.00 53.90 ? 111 TYR A O   1 
ATOM   164  C CB  . TYR A 1 111 ? 137.626 137.063 145.131 1.00 61.34 ? 111 TYR A CB  1 
ATOM   165  C CG  . TYR A 1 111 ? 138.405 137.017 143.813 1.00 63.48 ? 111 TYR A CG  1 
ATOM   166  C CD1 . TYR A 1 111 ? 139.769 136.727 143.766 1.00 63.42 ? 111 TYR A CD1 1 
ATOM   167  C CD2 . TYR A 1 111 ? 137.766 137.302 142.614 1.00 63.36 ? 111 TYR A CD2 1 
ATOM   168  C CE1 . TYR A 1 111 ? 140.454 136.700 142.572 1.00 63.09 ? 111 TYR A CE1 1 
ATOM   169  C CE2 . TYR A 1 111 ? 138.449 137.277 141.413 1.00 67.36 ? 111 TYR A CE2 1 
ATOM   170  C CZ  . TYR A 1 111 ? 139.792 136.977 141.400 1.00 66.86 ? 111 TYR A CZ  1 
ATOM   171  O OH  . TYR A 1 111 ? 140.478 136.952 140.209 1.00 64.92 ? 111 TYR A OH  1 
ATOM   172  N N   . PHE A 1 112 ? 136.549 136.420 148.132 1.00 49.22 ? 112 PHE A N   1 
ATOM   173  C CA  . PHE A 1 112 ? 136.127 136.899 149.442 1.00 46.08 ? 112 PHE A CA  1 
ATOM   174  C C   . PHE A 1 112 ? 137.068 136.426 150.542 1.00 39.44 ? 112 PHE A C   1 
ATOM   175  O O   . PHE A 1 112 ? 137.246 137.126 151.544 1.00 44.05 ? 112 PHE A O   1 
ATOM   176  C CB  . PHE A 1 112 ? 134.702 136.436 149.725 1.00 44.80 ? 112 PHE A CB  1 
ATOM   177  C CG  . PHE A 1 112 ? 134.052 137.138 150.874 1.00 39.64 ? 112 PHE A CG  1 
ATOM   178  C CD1 . PHE A 1 112 ? 133.381 138.328 150.683 1.00 41.84 ? 112 PHE A CD1 1 
ATOM   179  C CD2 . PHE A 1 112 ? 134.095 136.599 152.143 1.00 38.66 ? 112 PHE A CD2 1 
ATOM   180  C CE1 . PHE A 1 112 ? 132.775 138.971 151.737 1.00 42.48 ? 112 PHE A CE1 1 
ATOM   181  C CE2 . PHE A 1 112 ? 133.488 137.238 153.198 1.00 41.97 ? 112 PHE A CE2 1 
ATOM   182  C CZ  . PHE A 1 112 ? 132.827 138.425 152.995 1.00 41.29 ? 112 PHE A CZ  1 
ATOM   183  N N   . LEU A 1 113 ? 137.672 135.248 150.383 1.00 32.73 ? 113 LEU A N   1 
ATOM   184  C CA  . LEU A 1 113 ? 138.647 134.774 151.355 1.00 36.00 ? 113 LEU A CA  1 
ATOM   185  C C   . LEU A 1 113 ? 139.946 135.563 151.307 1.00 44.76 ? 113 LEU A C   1 
ATOM   186  O O   . LEU A 1 113 ? 140.689 135.567 152.294 1.00 42.38 ? 113 LEU A O   1 
ATOM   187  C CB  . LEU A 1 113 ? 138.944 133.289 151.135 1.00 28.50 ? 113 LEU A CB  1 
ATOM   188  C CG  . LEU A 1 113 ? 138.087 132.319 151.947 1.00 32.15 ? 113 LEU A CG  1 
ATOM   189  C CD1 . LEU A 1 113 ? 136.739 132.105 151.291 1.00 41.94 ? 113 LEU A CD1 1 
ATOM   190  C CD2 . LEU A 1 113 ? 138.807 131.008 152.108 1.00 36.27 ? 113 LEU A CD2 1 
ATOM   191  N N   . MET A 1 114 ? 140.247 136.214 150.183 1.00 48.97 ? 114 MET A N   1 
ATOM   192  C CA  . MET A 1 114 ? 141.382 137.127 150.140 1.00 43.18 ? 114 MET A CA  1 
ATOM   193  C C   . MET A 1 114 ? 141.095 138.402 150.917 1.00 49.49 ? 114 MET A C   1 
ATOM   194  O O   . MET A 1 114 ? 141.997 138.945 151.563 1.00 54.26 ? 114 MET A O   1 
ATOM   195  C CB  . MET A 1 114 ? 141.730 137.463 148.691 1.00 46.87 ? 114 MET A CB  1 
ATOM   196  C CG  . MET A 1 114 ? 143.092 138.127 148.521 1.00 49.15 ? 114 MET A CG  1 
ATOM   197  S SD  . MET A 1 114 ? 143.594 138.450 146.813 1.00 66.46 ? 114 MET A SD  1 
ATOM   198  C CE  . MET A 1 114 ? 142.092 139.087 146.070 1.00 52.88 ? 114 MET A CE  1 
ATOM   199  N N   . SER A 1 115 ? 139.854 138.891 150.867 1.00 44.60 ? 115 SER A N   1 
ATOM   200  C CA  . SER A 1 115 ? 139.477 140.037 151.685 1.00 41.11 ? 115 SER A CA  1 
ATOM   201  C C   . SER A 1 115 ? 139.510 139.700 153.168 1.00 40.17 ? 115 SER A C   1 
ATOM   202  O O   . SER A 1 115 ? 139.735 140.586 153.997 1.00 40.19 ? 115 SER A O   1 
ATOM   203  C CB  . SER A 1 115 ? 138.087 140.527 151.293 1.00 40.70 ? 115 SER A CB  1 
ATOM   204  O OG  . SER A 1 115 ? 137.518 141.298 152.332 1.00 41.77 ? 115 SER A OG  1 
ATOM   205  N N   . LEU A 1 116 ? 139.268 138.437 153.521 1.00 43.29 ? 116 LEU A N   1 
ATOM   206  C CA  . LEU A 1 116 ? 139.423 138.005 154.906 1.00 38.80 ? 116 LEU A CA  1 
ATOM   207  C C   . LEU A 1 116 ? 140.893 137.858 155.272 1.00 34.44 ? 116 LEU A C   1 
ATOM   208  O O   . LEU A 1 116 ? 141.289 138.181 156.395 1.00 39.23 ? 116 LEU A O   1 
ATOM   209  C CB  . LEU A 1 116 ? 138.670 136.689 155.128 1.00 40.03 ? 116 LEU A CB  1 
ATOM   210  C CG  . LEU A 1 116 ? 139.028 135.780 156.308 1.00 37.64 ? 116 LEU A CG  1 
ATOM   211  C CD1 . LEU A 1 116 ? 138.769 136.481 157.622 1.00 39.09 ? 116 LEU A CD1 1 
ATOM   212  C CD2 . LEU A 1 116 ? 138.218 134.504 156.223 1.00 40.63 ? 116 LEU A CD2 1 
ATOM   213  N N   . ALA A 1 117 ? 141.710 137.368 154.344 1.00 37.22 ? 117 ALA A N   1 
ATOM   214  C CA  . ALA A 1 117 ? 143.139 137.229 154.585 1.00 42.55 ? 117 ALA A CA  1 
ATOM   215  C C   . ALA A 1 117 ? 143.877 138.559 154.543 1.00 43.47 ? 117 ALA A C   1 
ATOM   216  O O   . ALA A 1 117 ? 145.030 138.619 154.982 1.00 37.21 ? 117 ALA A O   1 
ATOM   217  C CB  . ALA A 1 117 ? 143.750 136.272 153.562 1.00 44.74 ? 117 ALA A CB  1 
ATOM   218  N N   . ILE A 1 118 ? 143.252 139.615 154.011 1.00 43.48 ? 118 ILE A N   1 
ATOM   219  C CA  . ILE A 1 118 ? 143.833 140.954 154.056 1.00 40.72 ? 118 ILE A CA  1 
ATOM   220  C C   . ILE A 1 118 ? 143.476 141.670 155.350 1.00 46.00 ? 118 ILE A C   1 
ATOM   221  O O   . ILE A 1 118 ? 144.268 142.497 155.828 1.00 51.18 ? 118 ILE A O   1 
ATOM   222  C CB  . ILE A 1 118 ? 143.378 141.756 152.817 1.00 40.34 ? 118 ILE A CB  1 
ATOM   223  C CG1 . ILE A 1 118 ? 144.226 141.356 151.610 1.00 44.27 ? 118 ILE A CG1 1 
ATOM   224  C CG2 . ILE A 1 118 ? 143.498 143.272 153.041 1.00 42.82 ? 118 ILE A CG2 1 
ATOM   225  C CD1 . ILE A 1 118 ? 143.624 141.727 150.272 1.00 38.33 ? 118 ILE A CD1 1 
ATOM   226  N N   . ALA A 1 119 ? 142.318 141.380 155.936 1.00 42.65 ? 119 ALA A N   1 
ATOM   227  C CA  . ALA A 1 119 ? 141.954 141.922 157.235 1.00 40.83 ? 119 ALA A CA  1 
ATOM   228  C C   . ALA A 1 119 ? 142.754 141.313 158.375 1.00 40.16 ? 119 ALA A C   1 
ATOM   229  O O   . ALA A 1 119 ? 142.804 141.908 159.456 1.00 44.64 ? 119 ALA A O   1 
ATOM   230  C CB  . ALA A 1 119 ? 140.464 141.704 157.499 1.00 41.93 ? 119 ALA A CB  1 
ATOM   231  N N   . ASP A 1 120 ? 143.373 140.150 158.165 1.00 37.66 ? 120 ASP A N   1 
ATOM   232  C CA  . ASP A 1 120 ? 144.187 139.493 159.180 1.00 38.48 ? 120 ASP A CA  1 
ATOM   233  C C   . ASP A 1 120 ? 145.679 139.716 158.994 1.00 36.36 ? 120 ASP A C   1 
ATOM   234  O O   . ASP A 1 120 ? 146.408 139.782 159.988 1.00 42.00 ? 120 ASP A O   1 
ATOM   235  C CB  . ASP A 1 120 ? 143.902 137.991 159.190 1.00 43.32 ? 120 ASP A CB  1 
ATOM   236  C CG  . ASP A 1 120 ? 142.424 137.685 159.286 1.00 50.58 ? 120 ASP A CG  1 
ATOM   237  O OD1 . ASP A 1 120 ? 141.624 138.642 159.308 1.00 49.67 ? 120 ASP A OD1 1 
ATOM   238  O OD2 . ASP A 1 120 ? 142.060 136.493 159.341 1.00 46.90 ? 120 ASP A OD2 1 
ATOM   239  N N   . MET A 1 121 ? 146.160 139.824 157.755 1.00 41.19 ? 121 MET A N   1 
ATOM   240  C CA  . MET A 1 121 ? 147.565 140.164 157.554 1.00 42.72 ? 121 MET A CA  1 
ATOM   241  C C   . MET A 1 121 ? 147.850 141.570 158.061 1.00 39.04 ? 121 MET A C   1 
ATOM   242  O O   . MET A 1 121 ? 148.897 141.818 158.668 1.00 44.95 ? 121 MET A O   1 
ATOM   243  C CB  . MET A 1 121 ? 147.932 140.045 156.075 1.00 49.22 ? 121 MET A CB  1 
ATOM   244  C CG  . MET A 1 121 ? 149.446 140.129 155.784 1.00 43.37 ? 121 MET A CG  1 
ATOM   245  S SD  . MET A 1 121 ? 149.995 140.795 154.188 1.00 60.42 ? 121 MET A SD  1 
ATOM   246  C CE  . MET A 1 121 ? 148.897 142.177 153.870 1.00 48.99 ? 121 MET A CE  1 
ATOM   247  N N   . LEU A 1 122 ? 146.935 142.505 157.809 1.00 38.73 ? 122 LEU A N   1 
ATOM   248  C CA  . LEU A 1 122 ? 147.072 143.839 158.377 1.00 44.54 ? 122 LEU A CA  1 
ATOM   249  C C   . LEU A 1 122 ? 146.978 143.798 159.895 1.00 48.33 ? 122 LEU A C   1 
ATOM   250  O O   . LEU A 1 122 ? 147.715 144.512 160.584 1.00 45.94 ? 122 LEU A O   1 
ATOM   251  C CB  . LEU A 1 122 ? 146.001 144.761 157.798 1.00 35.27 ? 122 LEU A CB  1 
ATOM   252  C CG  . LEU A 1 122 ? 146.215 145.272 156.372 1.00 37.02 ? 122 LEU A CG  1 
ATOM   253  C CD1 . LEU A 1 122 ? 144.967 145.982 155.879 1.00 37.78 ? 122 LEU A CD1 1 
ATOM   254  C CD2 . LEU A 1 122 ? 147.422 146.194 156.283 1.00 44.62 ? 122 LEU A CD2 1 
ATOM   255  N N   . LEU A 1 123 ? 146.082 142.969 160.432 1.00 45.99 ? 123 LEU A N   1 
ATOM   256  C CA  . LEU A 1 123 ? 146.009 142.778 161.875 1.00 38.55 ? 123 LEU A CA  1 
ATOM   257  C C   . LEU A 1 123 ? 147.307 142.203 162.423 1.00 38.83 ? 123 LEU A C   1 
ATOM   258  O O   . LEU A 1 123 ? 147.673 142.473 163.571 1.00 42.57 ? 123 LEU A O   1 
ATOM   259  C CB  . LEU A 1 123 ? 144.831 141.861 162.211 1.00 40.23 ? 123 LEU A CB  1 
ATOM   260  C CG  . LEU A 1 123 ? 144.457 141.568 163.669 1.00 47.53 ? 123 LEU A CG  1 
ATOM   261  C CD1 . LEU A 1 123 ? 144.553 142.790 164.562 1.00 45.51 ? 123 LEU A CD1 1 
ATOM   262  C CD2 . LEU A 1 123 ? 143.056 140.978 163.727 1.00 44.17 ? 123 LEU A CD2 1 
ATOM   263  N N   . GLY A 1 124 ? 148.013 141.409 161.624 1.00 40.91 ? 124 GLY A N   1 
ATOM   264  C CA  . GLY A 1 124 ? 149.232 140.756 162.047 1.00 38.33 ? 124 GLY A CA  1 
ATOM   265  C C   . GLY A 1 124 ? 150.506 141.546 161.884 1.00 32.25 ? 124 GLY A C   1 
ATOM   266  O O   . GLY A 1 124 ? 151.565 141.058 162.288 1.00 33.27 ? 124 GLY A O   1 
ATOM   267  N N   . PHE A 1 125 ? 150.444 142.747 161.309 1.00 32.66 ? 125 PHE A N   1 
ATOM   268  C CA  . PHE A 1 125 ? 151.617 143.584 161.088 1.00 42.30 ? 125 PHE A CA  1 
ATOM   269  C C   . PHE A 1 125 ? 151.488 144.981 161.669 1.00 51.83 ? 125 PHE A C   1 
ATOM   270  O O   . PHE A 1 125 ? 152.509 145.590 161.988 1.00 48.92 ? 125 PHE A O   1 
ATOM   271  C CB  . PHE A 1 125 ? 151.912 143.705 159.585 1.00 45.98 ? 125 PHE A CB  1 
ATOM   272  C CG  . PHE A 1 125 ? 153.263 144.288 159.279 1.00 49.04 ? 125 PHE A CG  1 
ATOM   273  C CD1 . PHE A 1 125 ? 154.378 143.474 159.198 1.00 50.37 ? 125 PHE A CD1 1 
ATOM   274  C CD2 . PHE A 1 125 ? 153.418 145.649 159.075 1.00 46.29 ? 125 PHE A CD2 1 
ATOM   275  C CE1 . PHE A 1 125 ? 155.623 144.005 158.920 1.00 52.08 ? 125 PHE A CE1 1 
ATOM   276  C CE2 . PHE A 1 125 ? 154.659 146.186 158.798 1.00 44.92 ? 125 PHE A CE2 1 
ATOM   277  C CZ  . PHE A 1 125 ? 155.763 145.362 158.719 1.00 44.99 ? 125 PHE A CZ  1 
ATOM   278  N N   . LEU A 1 126 ? 150.272 145.504 161.810 1.00 45.38 ? 126 LEU A N   1 
ATOM   279  C CA  . LEU A 1 126 ? 150.045 146.832 162.366 1.00 39.95 ? 126 LEU A CA  1 
ATOM   280  C C   . LEU A 1 126 ? 149.649 146.795 163.833 1.00 36.57 ? 126 LEU A C   1 
ATOM   281  O O   . LEU A 1 126 ? 150.263 147.483 164.653 1.00 36.27 ? 126 LEU A O   1 
ATOM   282  C CB  . LEU A 1 126 ? 148.951 147.556 161.573 1.00 37.78 ? 126 LEU A CB  1 
ATOM   283  C CG  . LEU A 1 126 ? 149.213 147.853 160.095 1.00 32.07 ? 126 LEU A CG  1 
ATOM   284  C CD1 . LEU A 1 126 ? 148.007 148.543 159.497 1.00 35.40 ? 126 LEU A CD1 1 
ATOM   285  C CD2 . LEU A 1 126 ? 150.453 148.703 159.899 1.00 39.12 ? 126 LEU A CD2 1 
ATOM   286  N N   . VAL A 1 127 ? 148.650 145.994 164.179 1.00 40.90 ? 127 VAL A N   1 
ATOM   287  C CA  . VAL A 1 127 ? 148.076 145.976 165.518 1.00 42.98 ? 127 VAL A CA  1 
ATOM   288  C C   . VAL A 1 127 ? 148.801 144.993 166.424 1.00 42.45 ? 127 VAL A C   1 
ATOM   289  O O   . VAL A 1 127 ? 149.205 145.342 167.532 1.00 41.15 ? 127 VAL A O   1 
ATOM   290  C CB  . VAL A 1 127 ? 146.568 145.652 165.426 1.00 40.94 ? 127 VAL A CB  1 
ATOM   291  C CG1 . VAL A 1 127 ? 146.015 145.138 166.751 1.00 41.88 ? 127 VAL A CG1 1 
ATOM   292  C CG2 . VAL A 1 127 ? 145.799 146.872 164.967 1.00 39.63 ? 127 VAL A CG2 1 
ATOM   293  N N   . MET A 1 128 ? 148.959 143.756 165.973 1.00 40.20 ? 128 MET A N   1 
ATOM   294  C CA  . MET A 1 128 ? 149.501 142.688 166.802 1.00 31.50 ? 128 MET A CA  1 
ATOM   295  C C   . MET A 1 128 ? 150.925 142.963 167.277 1.00 35.63 ? 128 MET A C   1 
ATOM   296  O O   . MET A 1 128 ? 151.176 142.887 168.485 1.00 49.91 ? 128 MET A O   1 
ATOM   297  C CB  . MET A 1 128 ? 149.461 141.358 166.048 1.00 36.62 ? 128 MET A CB  1 
ATOM   298  C CG  . MET A 1 128 ? 148.253 140.512 166.395 1.00 46.43 ? 128 MET A CG  1 
ATOM   299  S SD  . MET A 1 128 ? 147.955 139.178 165.230 1.00 50.63 ? 128 MET A SD  1 
ATOM   300  C CE  . MET A 1 128 ? 149.503 138.311 165.369 1.00 39.32 ? 128 MET A CE  1 
ATOM   301  N N   . PRO A 1 129 ? 151.888 143.272 166.396 1.00 31.28 ? 129 PRO A N   1 
ATOM   302  C CA  . PRO A 1 129 ? 153.265 143.471 166.883 1.00 34.30 ? 129 PRO A CA  1 
ATOM   303  C C   . PRO A 1 129 ? 153.422 144.654 167.820 1.00 43.14 ? 129 PRO A C   1 
ATOM   304  O O   . PRO A 1 129 ? 154.378 144.672 168.605 1.00 45.62 ? 129 PRO A O   1 
ATOM   305  C CB  . PRO A 1 129 ? 154.087 143.672 165.604 1.00 35.83 ? 129 PRO A CB  1 
ATOM   306  C CG  . PRO A 1 129 ? 153.142 143.802 164.506 1.00 40.86 ? 129 PRO A CG  1 
ATOM   307  C CD  . PRO A 1 129 ? 151.806 143.323 164.927 1.00 38.25 ? 129 PRO A CD  1 
ATOM   308  N N   . VAL A 1 130 ? 152.528 145.642 167.763 1.00 45.89 ? 130 VAL A N   1 
ATOM   309  C CA  . VAL A 1 130 ? 152.566 146.723 168.741 1.00 39.56 ? 130 VAL A CA  1 
ATOM   310  C C   . VAL A 1 130 ? 152.323 146.169 170.137 1.00 41.77 ? 130 VAL A C   1 
ATOM   311  O O   . VAL A 1 130 ? 153.006 146.544 171.097 1.00 45.84 ? 130 VAL A O   1 
ATOM   312  C CB  . VAL A 1 130 ? 151.539 147.811 168.376 1.00 40.48 ? 130 VAL A CB  1 
ATOM   313  C CG1 . VAL A 1 130 ? 151.369 148.801 169.518 1.00 43.60 ? 130 VAL A CG1 1 
ATOM   314  C CG2 . VAL A 1 130 ? 151.957 148.535 167.107 1.00 42.88 ? 130 VAL A CG2 1 
ATOM   315  N N   . SER A 1 131 ? 151.353 145.260 170.269 1.00 46.92 ? 131 SER A N   1 
ATOM   316  C CA  . SER A 1 131 ? 151.059 144.639 171.554 1.00 43.07 ? 131 SER A CA  1 
ATOM   317  C C   . SER A 1 131 ? 152.229 143.826 172.089 1.00 41.16 ? 131 SER A C   1 
ATOM   318  O O   . SER A 1 131 ? 152.358 143.681 173.308 1.00 42.67 ? 131 SER A O   1 
ATOM   319  C CB  . SER A 1 131 ? 149.830 143.745 171.424 1.00 37.04 ? 131 SER A CB  1 
ATOM   320  O OG  . SER A 1 131 ? 148.878 144.325 170.557 1.00 37.53 ? 131 SER A OG  1 
ATOM   321  N N   . MET A 1 132 ? 153.078 143.286 171.212 1.00 47.48 ? 132 MET A N   1 
ATOM   322  C CA  . MET A 1 132 ? 154.274 142.599 171.684 1.00 45.42 ? 132 MET A CA  1 
ATOM   323  C C   . MET A 1 132 ? 155.208 143.558 172.403 1.00 50.51 ? 132 MET A C   1 
ATOM   324  O O   . MET A 1 132 ? 155.843 143.177 173.392 1.00 59.03 ? 132 MET A O   1 
ATOM   325  C CB  . MET A 1 132 ? 155.007 141.936 170.519 1.00 51.97 ? 132 MET A CB  1 
ATOM   326  C CG  . MET A 1 132 ? 155.631 140.587 170.856 1.00 48.19 ? 132 MET A CG  1 
ATOM   327  S SD  . MET A 1 132 ? 157.148 140.695 171.826 1.00 62.66 ? 132 MET A SD  1 
ATOM   328  C CE  . MET A 1 132 ? 158.260 141.521 170.692 1.00 55.33 ? 132 MET A CE  1 
ATOM   329  N N   . LEU A 1 133 ? 155.318 144.795 171.915 1.00 51.00 ? 133 LEU A N   1 
ATOM   330  C CA  . LEU A 1 133 ? 156.121 145.793 172.614 1.00 57.94 ? 133 LEU A CA  1 
ATOM   331  C C   . LEU A 1 133 ? 155.516 146.126 173.969 1.00 56.74 ? 133 LEU A C   1 
ATOM   332  O O   . LEU A 1 133 ? 156.242 146.309 174.953 1.00 56.98 ? 133 LEU A O   1 
ATOM   333  C CB  . LEU A 1 133 ? 156.249 147.056 171.763 1.00 58.61 ? 133 LEU A CB  1 
ATOM   334  C CG  . LEU A 1 133 ? 157.504 147.905 171.979 1.00 61.39 ? 133 LEU A CG  1 
ATOM   335  C CD1 . LEU A 1 133 ? 158.760 147.185 171.498 1.00 63.65 ? 133 LEU A CD1 1 
ATOM   336  C CD2 . LEU A 1 133 ? 157.355 149.249 171.288 1.00 58.46 ? 133 LEU A CD2 1 
ATOM   337  N N   . THR A 1 134 ? 154.187 146.214 174.037 1.00 50.29 ? 134 THR A N   1 
ATOM   338  C CA  . THR A 1 134 ? 153.524 146.479 175.307 1.00 48.22 ? 134 THR A CA  1 
ATOM   339  C C   . THR A 1 134 ? 153.779 145.349 176.298 1.00 49.91 ? 134 THR A C   1 
ATOM   340  O O   . THR A 1 134 ? 154.003 145.599 177.487 1.00 54.03 ? 134 THR A O   1 
ATOM   341  C CB  . THR A 1 134 ? 152.027 146.684 175.067 1.00 49.69 ? 134 THR A CB  1 
ATOM   342  O OG1 . THR A 1 134 ? 151.809 148.002 174.551 1.00 48.63 ? 134 THR A OG1 1 
ATOM   343  C CG2 . THR A 1 134 ? 151.221 146.528 176.347 1.00 54.93 ? 134 THR A CG2 1 
ATOM   344  N N   . ILE A 1 135 ? 153.751 144.101 175.826 1.00 53.71 ? 135 ILE A N   1 
ATOM   345  C CA  . ILE A 1 135 ? 154.054 142.965 176.692 1.00 52.79 ? 135 ILE A CA  1 
ATOM   346  C C   . ILE A 1 135 ? 155.484 143.064 177.205 1.00 51.28 ? 135 ILE A C   1 
ATOM   347  O O   . ILE A 1 135 ? 155.759 142.792 178.380 1.00 51.43 ? 135 ILE A O   1 
ATOM   348  C CB  . ILE A 1 135 ? 153.807 141.645 175.932 1.00 52.49 ? 135 ILE A CB  1 
ATOM   349  C CG1 . ILE A 1 135 ? 152.307 141.340 175.857 1.00 51.09 ? 135 ILE A CG1 1 
ATOM   350  C CG2 . ILE A 1 135 ? 154.552 140.469 176.571 1.00 50.77 ? 135 ILE A CG2 1 
ATOM   351  C CD1 . ILE A 1 135 ? 151.710 140.758 177.125 1.00 53.65 ? 135 ILE A CD1 1 
ATOM   352  N N   . LEU A 1 136 ? 156.417 143.448 176.331 1.00 61.69 ? 136 LEU A N   1 
ATOM   353  C CA  . LEU A 1 136 ? 157.818 143.550 176.728 1.00 66.13 ? 136 LEU A CA  1 
ATOM   354  C C   . LEU A 1 136 ? 158.012 144.619 177.798 1.00 68.92 ? 136 LEU A C   1 
ATOM   355  O O   . LEU A 1 136 ? 158.775 144.418 178.750 1.00 61.20 ? 136 LEU A O   1 
ATOM   356  C CB  . LEU A 1 136 ? 158.676 143.840 175.492 1.00 64.11 ? 136 LEU A CB  1 
ATOM   357  C CG  . LEU A 1 136 ? 160.169 144.174 175.628 1.00 68.50 ? 136 LEU A CG  1 
ATOM   358  C CD1 . LEU A 1 136 ? 160.989 142.899 175.721 1.00 65.47 ? 136 LEU A CD1 1 
ATOM   359  C CD2 . LEU A 1 136 ? 160.624 145.019 174.453 1.00 68.55 ? 136 LEU A CD2 1 
ATOM   360  N N   . TYR A 1 137 ? 157.334 145.758 177.662 1.00 73.59 ? 137 TYR A N   1 
ATOM   361  C CA  . TYR A 1 137 ? 157.472 146.879 178.582 1.00 68.59 ? 137 TYR A CA  1 
ATOM   362  C C   . TYR A 1 137 ? 156.509 146.806 179.763 1.00 69.88 ? 137 TYR A C   1 
ATOM   363  O O   . TYR A 1 137 ? 156.460 147.747 180.561 1.00 73.19 ? 137 TYR A O   1 
ATOM   364  C CB  . TYR A 1 137 ? 157.267 148.206 177.829 1.00 67.52 ? 137 TYR A CB  1 
ATOM   365  C CG  . TYR A 1 137 ? 158.433 148.717 176.978 1.00 75.92 ? 137 TYR A CG  1 
ATOM   366  C CD1 . TYR A 1 137 ? 159.739 148.255 177.146 1.00 74.79 ? 137 TYR A CD1 1 
ATOM   367  C CD2 . TYR A 1 137 ? 158.214 149.681 176.003 1.00 78.08 ? 137 TYR A CD2 1 
ATOM   368  C CE1 . TYR A 1 137 ? 160.776 148.733 176.372 1.00 74.64 ? 137 TYR A CE1 1 
ATOM   369  C CE2 . TYR A 1 137 ? 159.249 150.163 175.224 1.00 77.55 ? 137 TYR A CE2 1 
ATOM   370  C CZ  . TYR A 1 137 ? 160.526 149.686 175.413 1.00 76.44 ? 137 TYR A CZ  1 
ATOM   371  O OH  . TYR A 1 137 ? 161.555 150.165 174.637 1.00 73.74 ? 137 TYR A OH  1 
ATOM   372  N N   . GLY A 1 138 ? 155.753 145.721 179.901 1.00 68.89 ? 138 GLY A N   1 
ATOM   373  C CA  . GLY A 1 138 ? 154.929 145.533 181.079 1.00 68.80 ? 138 GLY A CA  1 
ATOM   374  C C   . GLY A 1 138 ? 153.815 146.549 181.218 1.00 67.52 ? 138 GLY A C   1 
ATOM   375  O O   . GLY A 1 138 ? 153.718 147.233 182.239 1.00 65.49 ? 138 GLY A O   1 
ATOM   376  N N   . TYR A 1 139 ? 152.992 146.672 180.177 1.00 66.56 ? 139 TYR A N   1 
ATOM   377  C CA  . TYR A 1 139 ? 151.762 147.463 180.112 1.00 64.94 ? 139 TYR A CA  1 
ATOM   378  C C   . TYR A 1 139 ? 152.009 148.964 180.007 1.00 63.76 ? 139 TYR A C   1 
ATOM   379  O O   . TYR A 1 139 ? 151.044 149.717 179.841 1.00 59.82 ? 139 TYR A O   1 
ATOM   380  C CB  . TYR A 1 139 ? 150.833 147.214 181.312 1.00 65.78 ? 139 TYR A CB  1 
ATOM   381  C CG  . TYR A 1 139 ? 150.097 145.888 181.313 1.00 64.83 ? 139 TYR A CG  1 
ATOM   382  C CD1 . TYR A 1 139 ? 150.520 144.813 180.536 1.00 62.93 ? 139 TYR A CD1 1 
ATOM   383  C CD2 . TYR A 1 139 ? 148.983 145.710 182.121 1.00 62.70 ? 139 TYR A CD2 1 
ATOM   384  C CE1 . TYR A 1 139 ? 149.848 143.616 180.557 1.00 67.85 ? 139 TYR A CE1 1 
ATOM   385  C CE2 . TYR A 1 139 ? 148.308 144.516 182.148 1.00 66.06 ? 139 TYR A CE2 1 
ATOM   386  C CZ  . TYR A 1 139 ? 148.743 143.473 181.365 1.00 69.90 ? 139 TYR A CZ  1 
ATOM   387  O OH  . TYR A 1 139 ? 148.067 142.282 181.396 1.00 58.31 ? 139 TYR A OH  1 
ATOM   388  N N   . ARG A 1 140 ? 153.254 149.428 180.081 1.00 64.72 ? 140 ARG A N   1 
ATOM   389  C CA  . ARG A 1 140 ? 153.558 150.839 179.891 1.00 63.56 ? 140 ARG A CA  1 
ATOM   390  C C   . ARG A 1 140 ? 153.600 151.153 178.402 1.00 69.09 ? 140 ARG A C   1 
ATOM   391  O O   . ARG A 1 140 ? 154.315 150.501 177.638 1.00 68.98 ? 140 ARG A O   1 
ATOM   392  C CB  . ARG A 1 140 ? 154.894 151.199 180.542 1.00 61.74 ? 140 ARG A CB  1 
ATOM   393  N N   . TRP A 1 141 ? 152.835 152.166 177.999 1.00 65.11 ? 141 TRP A N   1 
ATOM   394  C CA  . TRP A 1 141 ? 152.664 152.493 176.592 1.00 64.16 ? 141 TRP A CA  1 
ATOM   395  C C   . TRP A 1 141 ? 153.741 153.470 176.153 1.00 62.41 ? 141 TRP A C   1 
ATOM   396  O O   . TRP A 1 141 ? 153.732 154.621 176.617 1.00 61.69 ? 141 TRP A O   1 
ATOM   397  C CB  . TRP A 1 141 ? 151.288 153.101 176.362 1.00 61.23 ? 141 TRP A CB  1 
ATOM   398  C CG  . TRP A 1 141 ? 151.045 153.535 174.951 1.00 59.15 ? 141 TRP A CG  1 
ATOM   399  C CD1 . TRP A 1 141 ? 151.026 154.813 174.484 1.00 59.86 ? 141 TRP A CD1 1 
ATOM   400  C CD2 . TRP A 1 141 ? 150.770 152.693 173.826 1.00 57.16 ? 141 TRP A CD2 1 
ATOM   401  N NE1 . TRP A 1 141 ? 150.766 154.822 173.137 1.00 62.51 ? 141 TRP A NE1 1 
ATOM   402  C CE2 . TRP A 1 141 ? 150.602 153.532 172.709 1.00 59.15 ? 141 TRP A CE2 1 
ATOM   403  C CE3 . TRP A 1 141 ? 150.651 151.312 173.654 1.00 57.23 ? 141 TRP A CE3 1 
ATOM   404  C CZ2 . TRP A 1 141 ? 150.325 153.037 171.440 1.00 55.55 ? 141 TRP A CZ2 1 
ATOM   405  C CZ3 . TRP A 1 141 ? 150.377 150.824 172.394 1.00 58.94 ? 141 TRP A CZ3 1 
ATOM   406  C CH2 . TRP A 1 141 ? 150.214 151.683 171.303 1.00 53.42 ? 141 TRP A CH2 1 
ATOM   407  N N   . PRO A 1 142 ? 154.691 153.082 175.284 1.00 63.60 ? 142 PRO A N   1 
ATOM   408  C CA  . PRO A 1 142 ? 155.526 154.131 174.687 1.00 67.80 ? 142 PRO A CA  1 
ATOM   409  C C   . PRO A 1 142 ? 154.711 155.126 173.861 1.00 64.26 ? 142 PRO A C   1 
ATOM   410  O O   . PRO A 1 142 ? 155.273 155.841 173.035 1.00 61.24 ? 142 PRO A O   1 
ATOM   411  C CB  . PRO A 1 142 ? 156.501 153.353 173.789 1.00 71.15 ? 142 PRO A CB  1 
ATOM   412  C CG  . PRO A 1 142 ? 156.155 151.900 173.935 1.00 69.70 ? 142 PRO A CG  1 
ATOM   413  C CD  . PRO A 1 142 ? 155.307 151.754 175.144 1.00 59.29 ? 142 PRO A CD  1 
ATOM   414  N N   . SER A 1 145 ? 152.408 158.917 172.050 1.00 45.06 ? 145 SER A N   1 
ATOM   415  C CA  . SER A 1 145 ? 151.382 158.937 173.085 1.00 52.79 ? 145 SER A CA  1 
ATOM   416  C C   . SER A 1 145 ? 150.004 159.176 172.485 1.00 53.36 ? 145 SER A C   1 
ATOM   417  O O   . SER A 1 145 ? 149.002 158.681 172.997 1.00 53.70 ? 145 SER A O   1 
ATOM   418  C CB  . SER A 1 145 ? 151.686 160.014 174.124 1.00 55.90 ? 145 SER A CB  1 
ATOM   419  O OG  . SER A 1 145 ? 150.591 160.186 175.006 1.00 49.67 ? 145 SER A OG  1 
ATOM   420  N N   . LYS A 1 146 ? 149.960 159.945 171.401 1.00 60.71 ? 146 LYS A N   1 
ATOM   421  C CA  . LYS A 1 146 ? 148.726 160.176 170.664 1.00 62.64 ? 146 LYS A CA  1 
ATOM   422  C C   . LYS A 1 146 ? 148.412 159.065 169.672 1.00 62.70 ? 146 LYS A C   1 
ATOM   423  O O   . LYS A 1 146 ? 147.389 159.147 168.983 1.00 60.50 ? 146 LYS A O   1 
ATOM   424  C CB  . LYS A 1 146 ? 148.795 161.517 169.926 1.00 62.22 ? 146 LYS A CB  1 
ATOM   425  C CG  . LYS A 1 146 ? 147.459 162.243 169.826 1.00 63.53 ? 146 LYS A CG  1 
ATOM   426  C CD  . LYS A 1 146 ? 147.070 162.906 171.139 1.00 62.51 ? 146 LYS A CD  1 
ATOM   427  C CE  . LYS A 1 146 ? 145.714 163.582 171.039 1.00 64.60 ? 146 LYS A CE  1 
ATOM   428  N NZ  . LYS A 1 146 ? 145.127 163.841 172.382 1.00 63.77 ? 146 LYS A NZ  1 
ATOM   429  N N   . LEU A 1 147 ? 149.265 158.045 169.569 1.00 55.11 ? 147 LEU A N   1 
ATOM   430  C CA  . LEU A 1 147 ? 148.996 156.876 168.743 1.00 53.36 ? 147 LEU A CA  1 
ATOM   431  C C   . LEU A 1 147 ? 148.228 155.789 169.485 1.00 54.88 ? 147 LEU A C   1 
ATOM   432  O O   . LEU A 1 147 ? 147.856 154.788 168.866 1.00 58.79 ? 147 LEU A O   1 
ATOM   433  C CB  . LEU A 1 147 ? 150.312 156.289 168.207 1.00 54.66 ? 147 LEU A CB  1 
ATOM   434  C CG  . LEU A 1 147 ? 150.732 156.556 166.756 1.00 56.64 ? 147 LEU A CG  1 
ATOM   435  C CD1 . LEU A 1 147 ? 151.982 155.755 166.444 1.00 54.26 ? 147 LEU A CD1 1 
ATOM   436  C CD2 . LEU A 1 147 ? 149.646 156.214 165.744 1.00 56.68 ? 147 LEU A CD2 1 
ATOM   437  N N   . CYS A 1 148 ? 147.984 155.953 170.788 1.00 52.62 ? 148 CYS A N   1 
ATOM   438  C CA  . CYS A 1 148 ? 147.239 154.940 171.528 1.00 54.54 ? 148 CYS A CA  1 
ATOM   439  C C   . CYS A 1 148 ? 145.804 154.833 171.027 1.00 55.62 ? 148 CYS A C   1 
ATOM   440  O O   . CYS A 1 148 ? 145.279 153.727 170.867 1.00 52.81 ? 148 CYS A O   1 
ATOM   441  C CB  . CYS A 1 148 ? 147.259 155.260 173.020 1.00 57.76 ? 148 CYS A CB  1 
ATOM   442  S SG  . CYS A 1 148 ? 145.952 154.448 173.959 1.00 77.98 ? 148 CYS A SG  1 
ATOM   443  N N   . ALA A 1 149 ? 145.151 155.968 170.779 1.00 51.69 ? 149 ALA A N   1 
ATOM   444  C CA  . ALA A 1 149 ? 143.797 155.927 170.242 1.00 49.77 ? 149 ALA A CA  1 
ATOM   445  C C   . ALA A 1 149 ? 143.784 155.421 168.807 1.00 50.89 ? 149 ALA A C   1 
ATOM   446  O O   . ALA A 1 149 ? 142.795 154.822 168.372 1.00 46.47 ? 149 ALA A O   1 
ATOM   447  C CB  . ALA A 1 149 ? 143.158 157.310 170.325 1.00 50.43 ? 149 ALA A CB  1 
ATOM   448  N N   . VAL A 1 150 ? 144.859 155.664 168.056 1.00 55.29 ? 150 VAL A N   1 
ATOM   449  C CA  . VAL A 1 150 ? 144.946 155.149 166.693 1.00 53.47 ? 150 VAL A CA  1 
ATOM   450  C C   . VAL A 1 150 ? 145.130 153.639 166.705 1.00 51.06 ? 150 VAL A C   1 
ATOM   451  O O   . VAL A 1 150 ? 144.559 152.924 165.875 1.00 56.11 ? 150 VAL A O   1 
ATOM   452  C CB  . VAL A 1 150 ? 146.085 155.848 165.929 1.00 52.65 ? 150 VAL A CB  1 
ATOM   453  C CG1 . VAL A 1 150 ? 146.178 155.310 164.505 1.00 46.05 ? 150 VAL A CG1 1 
ATOM   454  C CG2 . VAL A 1 150 ? 145.876 157.360 165.928 1.00 58.03 ? 150 VAL A CG2 1 
ATOM   455  N N   . TRP A 1 151 ? 145.943 153.129 167.629 1.00 42.78 ? 151 TRP A N   1 
ATOM   456  C CA  . TRP A 1 151 ? 146.194 151.694 167.675 1.00 37.77 ? 151 TRP A CA  1 
ATOM   457  C C   . TRP A 1 151 ? 144.932 150.923 168.030 1.00 42.74 ? 151 TRP A C   1 
ATOM   458  O O   . TRP A 1 151 ? 144.688 149.840 167.490 1.00 48.57 ? 151 TRP A O   1 
ATOM   459  C CB  . TRP A 1 151 ? 147.308 151.396 168.672 1.00 46.13 ? 151 TRP A CB  1 
ATOM   460  C CG  . TRP A 1 151 ? 147.434 149.956 169.021 1.00 47.36 ? 151 TRP A CG  1 
ATOM   461  C CD1 . TRP A 1 151 ? 147.618 148.918 168.162 1.00 44.79 ? 151 TRP A CD1 1 
ATOM   462  C CD2 . TRP A 1 151 ? 147.404 149.390 170.333 1.00 45.22 ? 151 TRP A CD2 1 
ATOM   463  N NE1 . TRP A 1 151 ? 147.699 147.738 168.856 1.00 44.06 ? 151 TRP A NE1 1 
ATOM   464  C CE2 . TRP A 1 151 ? 147.570 148.002 170.193 1.00 39.69 ? 151 TRP A CE2 1 
ATOM   465  C CE3 . TRP A 1 151 ? 147.250 149.923 171.614 1.00 49.19 ? 151 TRP A CE3 1 
ATOM   466  C CZ2 . TRP A 1 151 ? 147.588 147.143 171.282 1.00 41.40 ? 151 TRP A CZ2 1 
ATOM   467  C CZ3 . TRP A 1 151 ? 147.268 149.068 172.692 1.00 47.07 ? 151 TRP A CZ3 1 
ATOM   468  C CH2 . TRP A 1 151 ? 147.436 147.695 172.521 1.00 43.64 ? 151 TRP A CH2 1 
ATOM   469  N N   . ILE A 1 152 ? 144.123 151.459 168.944 1.00 49.05 ? 152 ILE A N   1 
ATOM   470  C CA  . ILE A 1 152 ? 142.865 150.807 169.294 1.00 47.01 ? 152 ILE A CA  1 
ATOM   471  C C   . ILE A 1 152 ? 141.900 150.855 168.117 1.00 44.60 ? 152 ILE A C   1 
ATOM   472  O O   . ILE A 1 152 ? 141.112 149.927 167.908 1.00 40.28 ? 152 ILE A O   1 
ATOM   473  C CB  . ILE A 1 152 ? 142.263 151.457 170.552 1.00 50.84 ? 152 ILE A CB  1 
ATOM   474  C CG1 . ILE A 1 152 ? 143.111 151.132 171.780 1.00 47.54 ? 152 ILE A CG1 1 
ATOM   475  C CG2 . ILE A 1 152 ? 140.841 150.972 170.779 1.00 51.78 ? 152 ILE A CG2 1 
ATOM   476  C CD1 . ILE A 1 152 ? 142.994 152.152 172.875 1.00 44.36 ? 152 ILE A CD1 1 
ATOM   477  N N   . TYR A 1 153 ? 141.934 151.942 167.343 1.00 50.88 ? 153 TYR A N   1 
ATOM   478  C CA  . TYR A 1 153 ? 141.069 152.058 166.173 1.00 50.50 ? 153 TYR A CA  1 
ATOM   479  C C   . TYR A 1 153 ? 141.354 150.936 165.181 1.00 47.70 ? 153 TYR A C   1 
ATOM   480  O O   . TYR A 1 153 ? 140.429 150.284 164.686 1.00 46.26 ? 153 TYR A O   1 
ATOM   481  C CB  . TYR A 1 153 ? 141.285 153.431 165.526 1.00 51.58 ? 153 TYR A CB  1 
ATOM   482  C CG  . TYR A 1 153 ? 140.761 153.620 164.113 1.00 52.45 ? 153 TYR A CG  1 
ATOM   483  C CD1 . TYR A 1 153 ? 139.531 153.115 163.716 1.00 48.14 ? 153 TYR A CD1 1 
ATOM   484  C CD2 . TYR A 1 153 ? 141.529 154.275 163.162 1.00 53.54 ? 153 TYR A CD2 1 
ATOM   485  C CE1 . TYR A 1 153 ? 139.072 153.288 162.431 1.00 49.44 ? 153 TYR A CE1 1 
ATOM   486  C CE2 . TYR A 1 153 ? 141.077 154.446 161.873 1.00 52.41 ? 153 TYR A CE2 1 
ATOM   487  C CZ  . TYR A 1 153 ? 139.848 153.948 161.515 1.00 55.21 ? 153 TYR A CZ  1 
ATOM   488  O OH  . TYR A 1 153 ? 139.385 154.111 160.232 1.00 61.70 ? 153 TYR A OH  1 
ATOM   489  N N   . LEU A 1 154 ? 142.631 150.694 164.885 1.00 43.12 ? 154 LEU A N   1 
ATOM   490  C CA  . LEU A 1 154 ? 142.987 149.612 163.976 1.00 33.82 ? 154 LEU A CA  1 
ATOM   491  C C   . LEU A 1 154 ? 142.630 148.257 164.565 1.00 38.35 ? 154 LEU A C   1 
ATOM   492  O O   . LEU A 1 154 ? 142.177 147.366 163.840 1.00 48.33 ? 154 LEU A O   1 
ATOM   493  C CB  . LEU A 1 154 ? 144.483 149.663 163.668 1.00 37.00 ? 154 LEU A CB  1 
ATOM   494  C CG  . LEU A 1 154 ? 145.042 150.913 162.983 1.00 43.97 ? 154 LEU A CG  1 
ATOM   495  C CD1 . LEU A 1 154 ? 146.485 150.670 162.593 1.00 44.01 ? 154 LEU A CD1 1 
ATOM   496  C CD2 . LEU A 1 154 ? 144.228 151.326 161.769 1.00 43.91 ? 154 LEU A CD2 1 
ATOM   497  N N   . ASP A 1 155 ? 142.833 148.086 165.871 1.00 48.10 ? 155 ASP A N   1 
ATOM   498  C CA  . ASP A 1 155 ? 142.549 146.810 166.518 1.00 47.28 ? 155 ASP A CA  1 
ATOM   499  C C   . ASP A 1 155 ? 141.065 146.473 166.445 1.00 41.58 ? 155 ASP A C   1 
ATOM   500  O O   . ASP A 1 155 ? 140.689 145.328 166.176 1.00 28.84 ? 155 ASP A O   1 
ATOM   501  C CB  . ASP A 1 155 ? 143.022 146.868 167.969 1.00 45.25 ? 155 ASP A CB  1 
ATOM   502  C CG  . ASP A 1 155 ? 142.962 145.529 168.656 1.00 50.01 ? 155 ASP A CG  1 
ATOM   503  O OD1 . ASP A 1 155 ? 141.850 144.997 168.844 1.00 53.69 ? 155 ASP A OD1 1 
ATOM   504  O OD2 . ASP A 1 155 ? 144.036 145.012 169.021 1.00 53.23 ? 155 ASP A OD2 1 
ATOM   505  N N   . VAL A 1 156 ? 140.205 147.459 166.702 1.00 46.74 ? 156 VAL A N   1 
ATOM   506  C CA  . VAL A 1 156 ? 138.767 147.234 166.609 1.00 34.43 ? 156 VAL A CA  1 
ATOM   507  C C   . VAL A 1 156 ? 138.342 147.094 165.154 1.00 36.71 ? 156 VAL A C   1 
ATOM   508  O O   . VAL A 1 156 ? 137.408 146.350 164.836 1.00 37.51 ? 156 VAL A O   1 
ATOM   509  C CB  . VAL A 1 156 ? 138.003 148.368 167.314 1.00 37.41 ? 156 VAL A CB  1 
ATOM   510  C CG1 . VAL A 1 156 ? 136.506 148.184 167.136 1.00 45.18 ? 156 VAL A CG1 1 
ATOM   511  C CG2 . VAL A 1 156 ? 138.356 148.412 168.788 1.00 42.88 ? 156 VAL A CG2 1 
ATOM   512  N N   . LEU A 1 157 ? 138.994 147.829 164.250 1.00 40.97 ? 157 LEU A N   1 
ATOM   513  C CA  . LEU A 1 157 ? 138.602 147.795 162.844 1.00 37.55 ? 157 LEU A CA  1 
ATOM   514  C C   . LEU A 1 157 ? 138.884 146.429 162.229 1.00 40.47 ? 157 LEU A C   1 
ATOM   515  O O   . LEU A 1 157 ? 138.001 145.816 161.620 1.00 44.42 ? 157 LEU A O   1 
ATOM   516  C CB  . LEU A 1 157 ? 139.332 148.903 162.080 1.00 43.34 ? 157 LEU A CB  1 
ATOM   517  C CG  . LEU A 1 157 ? 139.199 149.014 160.554 1.00 47.03 ? 157 LEU A CG  1 
ATOM   518  C CD1 . LEU A 1 157 ? 137.982 149.839 160.192 1.00 48.26 ? 157 LEU A CD1 1 
ATOM   519  C CD2 . LEU A 1 157 ? 140.447 149.632 159.959 1.00 46.35 ? 157 LEU A CD2 1 
ATOM   520  N N   . PHE A 1 158 ? 140.111 145.931 162.385 1.00 36.14 ? 158 PHE A N   1 
ATOM   521  C CA  . PHE A 1 158 ? 140.470 144.656 161.778 1.00 30.09 ? 158 PHE A CA  1 
ATOM   522  C C   . PHE A 1 158 ? 139.858 143.479 162.522 1.00 36.20 ? 158 PHE A C   1 
ATOM   523  O O   . PHE A 1 158 ? 139.633 142.426 161.918 1.00 49.01 ? 158 PHE A O   1 
ATOM   524  C CB  . PHE A 1 158 ? 141.993 144.500 161.730 1.00 33.73 ? 158 PHE A CB  1 
ATOM   525  C CG  . PHE A 1 158 ? 142.704 145.537 160.884 1.00 43.44 ? 158 PHE A CG  1 
ATOM   526  C CD1 . PHE A 1 158 ? 142.129 146.061 159.738 1.00 41.02 ? 158 PHE A CD1 1 
ATOM   527  C CD2 . PHE A 1 158 ? 143.964 145.981 161.246 1.00 41.81 ? 158 PHE A CD2 1 
ATOM   528  C CE1 . PHE A 1 158 ? 142.792 146.997 158.979 1.00 36.10 ? 158 PHE A CE1 1 
ATOM   529  C CE2 . PHE A 1 158 ? 144.627 146.923 160.489 1.00 32.22 ? 158 PHE A CE2 1 
ATOM   530  C CZ  . PHE A 1 158 ? 144.040 147.430 159.356 1.00 32.21 ? 158 PHE A CZ  1 
ATOM   531  N N   . SER A 1 159 ? 139.589 143.624 163.819 1.00 34.15 ? 159 SER A N   1 
ATOM   532  C CA  . SER A 1 159 ? 138.926 142.552 164.552 1.00 33.21 ? 159 SER A CA  1 
ATOM   533  C C   . SER A 1 159 ? 137.463 142.421 164.148 1.00 32.19 ? 159 SER A C   1 
ATOM   534  O O   . SER A 1 159 ? 136.956 141.304 164.009 1.00 28.42 ? 159 SER A O   1 
ATOM   535  C CB  . SER A 1 159 ? 139.045 142.796 166.053 1.00 39.09 ? 159 SER A CB  1 
ATOM   536  O OG  . SER A 1 159 ? 140.400 142.756 166.459 1.00 43.41 ? 159 SER A OG  1 
ATOM   537  N N   . THR A 1 160 ? 136.768 143.546 163.963 1.00 42.37 ? 160 THR A N   1 
ATOM   538  C CA  . THR A 1 160 ? 135.385 143.493 163.501 1.00 33.10 ? 160 THR A CA  1 
ATOM   539  C C   . THR A 1 160 ? 135.303 143.157 162.020 1.00 36.66 ? 160 THR A C   1 
ATOM   540  O O   . THR A 1 160 ? 134.325 142.548 161.579 1.00 39.93 ? 160 THR A O   1 
ATOM   541  C CB  . THR A 1 160 ? 134.678 144.820 163.765 1.00 35.58 ? 160 THR A CB  1 
ATOM   542  O OG1 . THR A 1 160 ? 135.042 145.315 165.057 1.00 37.89 ? 160 THR A OG1 1 
ATOM   543  C CG2 . THR A 1 160 ? 133.171 144.643 163.703 1.00 41.57 ? 160 THR A CG2 1 
ATOM   544  N N   . ALA A 1 161 ? 136.300 143.563 161.233 1.00 39.83 ? 161 ALA A N   1 
ATOM   545  C CA  . ALA A 1 161 ? 136.320 143.175 159.829 1.00 36.03 ? 161 ALA A CA  1 
ATOM   546  C C   . ALA A 1 161 ? 136.495 141.675 159.675 1.00 33.48 ? 161 ALA A C   1 
ATOM   547  O O   . ALA A 1 161 ? 135.964 141.083 158.731 1.00 30.58 ? 161 ALA A O   1 
ATOM   548  C CB  . ALA A 1 161 ? 137.436 143.911 159.094 1.00 40.78 ? 161 ALA A CB  1 
ATOM   549  N N   . SER A 1 162 ? 137.245 141.048 160.582 1.00 31.41 ? 162 SER A N   1 
ATOM   550  C CA  . SER A 1 162 ? 137.432 139.605 160.515 1.00 27.84 ? 162 SER A CA  1 
ATOM   551  C C   . SER A 1 162 ? 136.174 138.861 160.943 1.00 35.36 ? 162 SER A C   1 
ATOM   552  O O   . SER A 1 162 ? 135.771 137.897 160.288 1.00 41.17 ? 162 SER A O   1 
ATOM   553  C CB  . SER A 1 162 ? 138.617 139.196 161.384 1.00 37.42 ? 162 SER A CB  1 
ATOM   554  O OG  . SER A 1 162 ? 138.794 137.793 161.370 1.00 48.64 ? 162 SER A OG  1 
ATOM   555  N N   . ILE A 1 163 ? 135.537 139.296 162.032 1.00 39.50 ? 163 ILE A N   1 
ATOM   556  C CA  . ILE A 1 163 ? 134.396 138.560 162.574 1.00 35.47 ? 163 ILE A CA  1 
ATOM   557  C C   . ILE A 1 163 ? 133.246 138.536 161.576 1.00 32.40 ? 163 ILE A C   1 
ATOM   558  O O   . ILE A 1 163 ? 132.601 137.500 161.386 1.00 34.55 ? 163 ILE A O   1 
ATOM   559  C CB  . ILE A 1 163 ? 133.955 139.155 163.925 1.00 30.73 ? 163 ILE A CB  1 
ATOM   560  C CG1 . ILE A 1 163 ? 135.017 138.916 164.998 1.00 28.36 ? 163 ILE A CG1 1 
ATOM   561  C CG2 . ILE A 1 163 ? 132.640 138.540 164.376 1.00 27.21 ? 163 ILE A CG2 1 
ATOM   562  C CD1 . ILE A 1 163 ? 134.968 139.904 166.133 1.00 33.55 ? 163 ILE A CD1 1 
ATOM   563  N N   . MET A 1 164 ? 132.959 139.668 160.935 1.00 32.91 ? 164 MET A N   1 
ATOM   564  C CA  . MET A 1 164 ? 131.868 139.717 159.969 1.00 27.64 ? 164 MET A CA  1 
ATOM   565  C C   . MET A 1 164 ? 132.249 139.136 158.616 1.00 29.69 ? 164 MET A C   1 
ATOM   566  O O   . MET A 1 164 ? 131.355 138.854 157.813 1.00 34.06 ? 164 MET A O   1 
ATOM   567  C CB  . MET A 1 164 ? 131.341 141.147 159.779 1.00 25.50 ? 164 MET A CB  1 
ATOM   568  C CG  . MET A 1 164 ? 131.242 142.014 161.038 1.00 34.24 ? 164 MET A CG  1 
ATOM   569  S SD  . MET A 1 164 ? 129.696 141.707 161.900 1.00 52.10 ? 164 MET A SD  1 
ATOM   570  C CE  . MET A 1 164 ? 128.654 142.957 161.186 1.00 34.19 ? 164 MET A CE  1 
ATOM   571  N N   . HIS A 1 165 ? 133.538 138.952 158.334 1.00 36.31 ? 165 HIS A N   1 
ATOM   572  C CA  . HIS A 1 165 ? 133.910 138.135 157.185 1.00 30.91 ? 165 HIS A CA  1 
ATOM   573  C C   . HIS A 1 165 ? 133.450 136.700 157.381 1.00 30.32 ? 165 HIS A C   1 
ATOM   574  O O   . HIS A 1 165 ? 132.920 136.078 156.456 1.00 42.53 ? 165 HIS A O   1 
ATOM   575  C CB  . HIS A 1 165 ? 135.420 138.175 156.962 1.00 35.04 ? 165 HIS A CB  1 
ATOM   576  C CG  . HIS A 1 165 ? 135.874 139.311 156.105 1.00 30.79 ? 165 HIS A CG  1 
ATOM   577  N ND1 . HIS A 1 165 ? 136.683 140.319 156.579 1.00 37.26 ? 165 HIS A ND1 1 
ATOM   578  C CD2 . HIS A 1 165 ? 135.634 139.600 154.806 1.00 30.78 ? 165 HIS A CD2 1 
ATOM   579  C CE1 . HIS A 1 165 ? 136.923 141.180 155.608 1.00 36.23 ? 165 HIS A CE1 1 
ATOM   580  N NE2 . HIS A 1 165 ? 136.298 140.767 154.522 1.00 40.96 ? 165 HIS A NE2 1 
ATOM   581  N N   . LEU A 1 166 ? 133.641 136.163 158.586 1.00 37.90 ? 166 LEU A N   1 
ATOM   582  C CA  . LEU A 1 166 ? 133.200 134.805 158.874 1.00 38.79 ? 166 LEU A CA  1 
ATOM   583  C C   . LEU A 1 166 ? 131.681 134.711 158.944 1.00 35.69 ? 166 LEU A C   1 
ATOM   584  O O   . LEU A 1 166 ? 131.109 133.689 158.551 1.00 34.02 ? 166 LEU A O   1 
ATOM   585  C CB  . LEU A 1 166 ? 133.829 134.327 160.181 1.00 36.35 ? 166 LEU A CB  1 
ATOM   586  C CG  . LEU A 1 166 ? 135.337 134.531 160.342 1.00 29.05 ? 166 LEU A CG  1 
ATOM   587  C CD1 . LEU A 1 166 ? 135.845 133.798 161.568 1.00 31.89 ? 166 LEU A CD1 1 
ATOM   588  C CD2 . LEU A 1 166 ? 136.095 134.097 159.108 1.00 35.80 ? 166 LEU A CD2 1 
ATOM   589  N N   . CYS A 1 167 ? 131.012 135.749 159.450 1.00 30.10 ? 167 CYS A N   1 
ATOM   590  C CA  . CYS A 1 167 ? 129.553 135.747 159.467 1.00 25.44 ? 167 CYS A CA  1 
ATOM   591  C C   . CYS A 1 167 ? 128.986 135.778 158.055 1.00 35.20 ? 167 CYS A C   1 
ATOM   592  O O   . CYS A 1 167 ? 128.014 135.076 157.757 1.00 43.37 ? 167 CYS A O   1 
ATOM   593  C CB  . CYS A 1 167 ? 129.032 136.935 160.270 1.00 25.51 ? 167 CYS A CB  1 
ATOM   594  S SG  . CYS A 1 167 ? 127.239 136.995 160.407 1.00 30.19 ? 167 CYS A SG  1 
ATOM   595  N N   . ALA A 1 168 ? 129.569 136.595 157.175 1.00 32.67 ? 168 ALA A N   1 
ATOM   596  C CA  . ALA A 1 168 ? 129.122 136.623 155.788 1.00 25.65 ? 168 ALA A CA  1 
ATOM   597  C C   . ALA A 1 168 ? 129.385 135.295 155.096 1.00 27.43 ? 168 ALA A C   1 
ATOM   598  O O   . ALA A 1 168 ? 128.555 134.837 154.305 1.00 33.08 ? 168 ALA A O   1 
ATOM   599  C CB  . ALA A 1 168 ? 129.813 137.755 155.033 1.00 28.32 ? 168 ALA A CB  1 
ATOM   600  N N   . ILE A 1 169 ? 130.530 134.671 155.374 1.00 26.76 ? 169 ILE A N   1 
ATOM   601  C CA  . ILE A 1 169 ? 130.809 133.354 154.816 1.00 15.83 ? 169 ILE A CA  1 
ATOM   602  C C   . ILE A 1 169 ? 129.784 132.347 155.315 1.00 27.41 ? 169 ILE A C   1 
ATOM   603  O O   . ILE A 1 169 ? 129.245 131.556 154.535 1.00 45.52 ? 169 ILE A O   1 
ATOM   604  C CB  . ILE A 1 169 ? 132.246 132.922 155.165 1.00 19.62 ? 169 ILE A CB  1 
ATOM   605  C CG1 . ILE A 1 169 ? 133.254 133.743 154.355 1.00 31.35 ? 169 ILE A CG1 1 
ATOM   606  C CG2 . ILE A 1 169 ? 132.439 131.434 154.888 1.00 32.48 ? 169 ILE A CG2 1 
ATOM   607  C CD1 . ILE A 1 169 ? 134.684 133.675 154.868 1.00 30.54 ? 169 ILE A CD1 1 
ATOM   608  N N   . SER A 1 170 ? 129.489 132.366 156.616 1.00 31.84 ? 170 SER A N   1 
ATOM   609  C CA  . SER A 1 170 ? 128.533 131.417 157.178 1.00 29.05 ? 170 SER A CA  1 
ATOM   610  C C   . SER A 1 170 ? 127.136 131.623 156.606 1.00 27.55 ? 170 SER A C   1 
ATOM   611  O O   . SER A 1 170 ? 126.455 130.653 156.258 1.00 28.98 ? 170 SER A O   1 
ATOM   612  C CB  . SER A 1 170 ? 128.511 131.547 158.698 1.00 34.71 ? 170 SER A CB  1 
ATOM   613  O OG  . SER A 1 170 ? 127.393 130.882 159.249 1.00 44.29 ? 170 SER A OG  1 
ATOM   614  N N   . LEU A 1 171 ? 126.688 132.876 156.505 1.00 26.25 ? 171 LEU A N   1 
ATOM   615  C CA  . LEU A 1 171 ? 125.371 133.140 155.932 1.00 27.13 ? 171 LEU A CA  1 
ATOM   616  C C   . LEU A 1 171 ? 125.321 132.784 154.454 1.00 30.70 ? 171 LEU A C   1 
ATOM   617  O O   . LEU A 1 171 ? 124.319 132.235 153.984 1.00 30.74 ? 171 LEU A O   1 
ATOM   618  C CB  . LEU A 1 171 ? 124.989 134.608 156.127 1.00 25.41 ? 171 LEU A CB  1 
ATOM   619  C CG  . LEU A 1 171 ? 124.115 134.950 157.333 1.00 27.25 ? 171 LEU A CG  1 
ATOM   620  C CD1 . LEU A 1 171 ? 124.040 136.453 157.511 1.00 27.62 ? 171 LEU A CD1 1 
ATOM   621  C CD2 . LEU A 1 171 ? 122.717 134.373 157.179 1.00 31.33 ? 171 LEU A CD2 1 
ATOM   622  N N   . ASP A 1 172 ? 126.378 133.097 153.703 1.00 34.02 ? 172 ASP A N   1 
ATOM   623  C CA  . ASP A 1 172 ? 126.426 132.703 152.301 1.00 26.26 ? 172 ASP A CA  1 
ATOM   624  C C   . ASP A 1 172 ? 126.469 131.192 152.151 1.00 23.24 ? 172 ASP A C   1 
ATOM   625  O O   . ASP A 1 172 ? 125.841 130.643 151.241 1.00 29.67 ? 172 ASP A O   1 
ATOM   626  C CB  . ASP A 1 172 ? 127.640 133.327 151.621 1.00 29.46 ? 172 ASP A CB  1 
ATOM   627  C CG  . ASP A 1 172 ? 127.784 132.893 150.182 1.00 37.70 ? 172 ASP A CG  1 
ATOM   628  O OD1 . ASP A 1 172 ? 126.754 132.778 149.489 1.00 38.49 ? 172 ASP A OD1 1 
ATOM   629  O OD2 . ASP A 1 172 ? 128.927 132.660 149.742 1.00 46.72 ? 172 ASP A OD2 1 
ATOM   630  N N   . ARG A 1 173 ? 127.199 130.506 153.031 1.00 27.06 ? 173 ARG A N   1 
ATOM   631  C CA  . ARG A 1 173 ? 127.305 129.056 152.954 1.00 23.50 ? 173 ARG A CA  1 
ATOM   632  C C   . ARG A 1 173 ? 125.984 128.361 153.247 1.00 30.27 ? 173 ARG A C   1 
ATOM   633  O O   . ARG A 1 173 ? 125.787 127.227 152.802 1.00 37.82 ? 173 ARG A O   1 
ATOM   634  C CB  . ARG A 1 173 ? 128.377 128.569 153.924 1.00 21.06 ? 173 ARG A CB  1 
ATOM   635  C CG  . ARG A 1 173 ? 128.957 127.223 153.595 1.00 31.95 ? 173 ARG A CG  1 
ATOM   636  C CD  . ARG A 1 173 ? 130.091 126.884 154.545 1.00 36.62 ? 173 ARG A CD  1 
ATOM   637  N NE  . ARG A 1 173 ? 131.320 127.603 154.223 1.00 39.46 ? 173 ARG A NE  1 
ATOM   638  C CZ  . ARG A 1 173 ? 132.328 127.813 155.062 1.00 37.94 ? 173 ARG A CZ  1 
ATOM   639  N NH1 . ARG A 1 173 ? 132.285 127.410 156.322 1.00 36.46 ? 173 ARG A NH1 1 
ATOM   640  N NH2 . ARG A 1 173 ? 133.414 128.442 154.622 1.00 35.67 ? 173 ARG A NH2 1 
ATOM   641  N N   . TYR A 1 174 ? 125.083 128.997 153.996 1.00 29.09 ? 174 TYR A N   1 
ATOM   642  C CA  . TYR A 1 174 ? 123.788 128.382 154.268 1.00 20.94 ? 174 TYR A CA  1 
ATOM   643  C C   . TYR A 1 174 ? 122.867 128.458 153.059 1.00 24.04 ? 174 TYR A C   1 
ATOM   644  O O   . TYR A 1 174 ? 122.186 127.481 152.733 1.00 35.42 ? 174 TYR A O   1 
ATOM   645  C CB  . TYR A 1 174 ? 123.138 129.044 155.477 1.00 26.54 ? 174 TYR A CB  1 
ATOM   646  C CG  . TYR A 1 174 ? 121.643 128.869 155.549 1.00 21.79 ? 174 TYR A CG  1 
ATOM   647  C CD1 . TYR A 1 174 ? 121.079 127.620 155.749 1.00 23.96 ? 174 TYR A CD1 1 
ATOM   648  C CD2 . TYR A 1 174 ? 120.796 129.957 155.431 1.00 21.36 ? 174 TYR A CD2 1 
ATOM   649  C CE1 . TYR A 1 174 ? 119.715 127.460 155.818 1.00 27.07 ? 174 TYR A CE1 1 
ATOM   650  C CE2 . TYR A 1 174 ? 119.433 129.808 155.500 1.00 27.39 ? 174 TYR A CE2 1 
ATOM   651  C CZ  . TYR A 1 174 ? 118.896 128.558 155.694 1.00 31.60 ? 174 TYR A CZ  1 
ATOM   652  O OH  . TYR A 1 174 ? 117.531 128.410 155.762 1.00 33.90 ? 174 TYR A OH  1 
ATOM   653  N N   . VAL A 1 175 ? 122.820 129.609 152.387 1.00 28.58 ? 175 VAL A N   1 
ATOM   654  C CA  . VAL A 1 175 ? 121.954 129.741 151.219 1.00 27.88 ? 175 VAL A CA  1 
ATOM   655  C C   . VAL A 1 175 ? 122.448 128.847 150.091 1.00 24.20 ? 175 VAL A C   1 
ATOM   656  O O   . VAL A 1 175 ? 121.654 128.317 149.307 1.00 17.92 ? 175 VAL A O   1 
ATOM   657  C CB  . VAL A 1 175 ? 121.861 131.211 150.774 1.00 26.25 ? 175 VAL A CB  1 
ATOM   658  C CG1 . VAL A 1 175 ? 120.975 131.329 149.545 1.00 24.77 ? 175 VAL A CG1 1 
ATOM   659  C CG2 . VAL A 1 175 ? 121.332 132.082 151.906 1.00 27.70 ? 175 VAL A CG2 1 
ATOM   660  N N   . ALA A 1 176 ? 123.764 128.678 149.980 1.00 27.47 ? 176 ALA A N   1 
ATOM   661  C CA  . ALA A 1 176 ? 124.333 127.781 148.986 1.00 23.37 ? 176 ALA A CA  1 
ATOM   662  C C   . ALA A 1 176 ? 124.059 126.313 149.281 1.00 23.96 ? 176 ALA A C   1 
ATOM   663  O O   . ALA A 1 176 ? 124.294 125.479 148.403 1.00 41.93 ? 176 ALA A O   1 
ATOM   664  C CB  . ALA A 1 176 ? 125.841 128.004 148.888 1.00 20.93 ? 176 ALA A CB  1 
ATOM   665  N N   . ILE A 1 177 ? 123.581 125.982 150.480 1.00 25.10 ? 177 ILE A N   1 
ATOM   666  C CA  . ILE A 1 177 ? 123.308 124.608 150.875 1.00 25.43 ? 177 ILE A CA  1 
ATOM   667  C C   . ILE A 1 177 ? 121.812 124.346 150.995 1.00 21.45 ? 177 ILE A C   1 
ATOM   668  O O   . ILE A 1 177 ? 121.356 123.228 150.749 1.00 24.75 ? 177 ILE A O   1 
ATOM   669  C CB  . ILE A 1 177 ? 124.043 124.279 152.194 1.00 25.56 ? 177 ILE A CB  1 
ATOM   670  C CG1 . ILE A 1 177 ? 125.532 124.077 151.909 1.00 18.18 ? 177 ILE A CG1 1 
ATOM   671  C CG2 . ILE A 1 177 ? 123.461 123.040 152.869 1.00 29.77 ? 177 ILE A CG2 1 
ATOM   672  C CD1 . ILE A 1 177 ? 126.419 124.166 153.122 1.00 27.76 ? 177 ILE A CD1 1 
ATOM   673  N N   . GLN A 1 178 ? 121.033 125.356 151.379 1.00 24.80 ? 178 GLN A N   1 
ATOM   674  C CA  . GLN A 1 178 ? 119.593 125.168 151.515 1.00 22.27 ? 178 GLN A CA  1 
ATOM   675  C C   . GLN A 1 178 ? 118.932 125.017 150.151 1.00 39.20 ? 178 GLN A C   1 
ATOM   676  O O   . GLN A 1 178 ? 118.303 123.993 149.863 1.00 43.38 ? 178 GLN A O   1 
ATOM   677  C CB  . GLN A 1 178 ? 118.990 126.344 152.286 1.00 28.54 ? 178 GLN A CB  1 
ATOM   678  C CG  . GLN A 1 178 ? 117.472 126.317 152.433 1.00 36.84 ? 178 GLN A CG  1 
ATOM   679  C CD  . GLN A 1 178 ? 116.969 125.057 153.105 1.00 43.45 ? 178 GLN A CD  1 
ATOM   680  O OE1 . GLN A 1 178 ? 117.539 124.599 154.095 1.00 43.89 ? 178 GLN A OE1 1 
ATOM   681  N NE2 . GLN A 1 178 ? 115.891 124.492 152.574 1.00 44.19 ? 178 GLN A NE2 1 
ATOM   682  N N   . ASN A 1 179 ? 119.067 126.033 149.299 1.00 43.04 ? 179 ASN A N   1 
ATOM   683  C CA  . ASN A 1 179 ? 118.424 126.083 147.985 1.00 42.69 ? 179 ASN A CA  1 
ATOM   684  C C   . ASN A 1 179 ? 119.494 126.413 146.955 1.00 36.25 ? 179 ASN A C   1 
ATOM   685  O O   . ASN A 1 179 ? 119.594 127.559 146.500 1.00 44.58 ? 179 ASN A O   1 
ATOM   686  C CB  . ASN A 1 179 ? 117.303 127.116 147.958 1.00 43.97 ? 179 ASN A CB  1 
ATOM   687  C CG  . ASN A 1 179 ? 117.656 128.369 148.718 1.00 46.78 ? 179 ASN A CG  1 
ATOM   688  O OD1 . ASN A 1 179 ? 118.826 128.731 148.822 1.00 50.69 ? 179 ASN A OD1 1 
ATOM   689  N ND2 . ASN A 1 179 ? 116.648 129.038 149.262 1.00 46.60 ? 179 ASN A ND2 1 
ATOM   690  N N   . PRO A 1 180 ? 120.329 125.440 146.575 1.00 14.35 ? 180 PRO A N   1 
ATOM   691  C CA  . PRO A 1 180 ? 121.431 125.749 145.652 1.00 21.57 ? 180 PRO A CA  1 
ATOM   692  C C   . PRO A 1 180 ? 120.984 126.196 144.272 1.00 30.32 ? 180 PRO A C   1 
ATOM   693  O O   . PRO A 1 180 ? 121.758 126.875 143.590 1.00 41.07 ? 180 PRO A O   1 
ATOM   694  C CB  . PRO A 1 180 ? 122.215 124.434 145.582 1.00 25.90 ? 180 PRO A CB  1 
ATOM   695  C CG  . PRO A 1 180 ? 121.300 123.394 146.068 1.00 27.46 ? 180 PRO A CG  1 
ATOM   696  C CD  . PRO A 1 180 ? 120.340 124.031 146.999 1.00 18.56 ? 180 PRO A CD  1 
ATOM   697  N N   . ILE A 1 181 ? 119.779 125.839 143.827 1.00 33.34 ? 181 ILE A N   1 
ATOM   698  C CA  . ILE A 1 181 ? 119.342 126.245 142.494 1.00 31.56 ? 181 ILE A CA  1 
ATOM   699  C C   . ILE A 1 181 ? 119.148 127.754 142.435 1.00 40.41 ? 181 ILE A C   1 
ATOM   700  O O   . ILE A 1 181 ? 119.648 128.423 141.524 1.00 45.00 ? 181 ILE A O   1 
ATOM   701  C CB  . ILE A 1 181 ? 118.061 125.489 142.093 1.00 36.99 ? 181 ILE A CB  1 
ATOM   702  C CG1 . ILE A 1 181 ? 118.406 124.032 141.763 1.00 38.03 ? 181 ILE A CG1 1 
ATOM   703  C CG2 . ILE A 1 181 ? 117.366 126.184 140.903 1.00 36.04 ? 181 ILE A CG2 1 
ATOM   704  C CD1 . ILE A 1 181 ? 117.207 123.117 141.566 1.00 31.45 ? 181 ILE A CD1 1 
ATOM   705  N N   . HIS A 1 182 ? 118.426 128.316 143.405 1.00 50.62 ? 182 HIS A N   1 
ATOM   706  C CA  . HIS A 1 182 ? 118.153 129.748 143.405 1.00 41.84 ? 182 HIS A CA  1 
ATOM   707  C C   . HIS A 1 182 ? 119.352 130.581 143.829 1.00 31.54 ? 182 HIS A C   1 
ATOM   708  O O   . HIS A 1 182 ? 119.316 131.804 143.671 1.00 42.85 ? 182 HIS A O   1 
ATOM   709  C CB  . HIS A 1 182 ? 116.969 130.065 144.327 1.00 44.78 ? 182 HIS A CB  1 
ATOM   710  C CG  . HIS A 1 182 ? 115.625 129.893 143.683 1.00 51.47 ? 182 HIS A CG  1 
ATOM   711  N ND1 . HIS A 1 182 ? 114.553 129.335 144.346 1.00 53.10 ? 182 HIS A ND1 1 
ATOM   712  C CD2 . HIS A 1 182 ? 115.171 130.223 142.450 1.00 46.03 ? 182 HIS A CD2 1 
ATOM   713  C CE1 . HIS A 1 182 ? 113.503 129.314 143.544 1.00 46.78 ? 182 HIS A CE1 1 
ATOM   714  N NE2 . HIS A 1 182 ? 113.852 129.846 142.388 1.00 44.18 ? 182 HIS A NE2 1 
ATOM   715  N N   . HIS A 1 183 ? 120.402 129.963 144.365 1.00 30.99 ? 183 HIS A N   1 
ATOM   716  C CA  . HIS A 1 183 ? 121.617 130.687 144.711 1.00 39.88 ? 183 HIS A CA  1 
ATOM   717  C C   . HIS A 1 183 ? 122.541 130.855 143.514 1.00 40.80 ? 183 HIS A C   1 
ATOM   718  O O   . HIS A 1 183 ? 123.194 131.895 143.380 1.00 47.06 ? 183 HIS A O   1 
ATOM   719  C CB  . HIS A 1 183 ? 122.358 129.963 145.832 1.00 37.10 ? 183 HIS A CB  1 
ATOM   720  C CG  . HIS A 1 183 ? 123.771 130.418 146.010 1.00 33.43 ? 183 HIS A CG  1 
ATOM   721  N ND1 . HIS A 1 183 ? 124.838 129.781 145.416 1.00 33.66 ? 183 HIS A ND1 1 
ATOM   722  C CD2 . HIS A 1 183 ? 124.293 131.445 146.720 1.00 35.36 ? 183 HIS A CD2 1 
ATOM   723  C CE1 . HIS A 1 183 ? 125.957 130.396 145.751 1.00 41.66 ? 183 HIS A CE1 1 
ATOM   724  N NE2 . HIS A 1 183 ? 125.654 131.409 146.543 1.00 43.12 ? 183 HIS A NE2 1 
ATOM   725  N N   . SER A 1 184 ? 122.618 129.850 142.642 1.00 36.65 ? 184 SER A N   1 
ATOM   726  C CA  . SER A 1 184 ? 123.453 129.956 141.455 1.00 41.36 ? 184 SER A CA  1 
ATOM   727  C C   . SER A 1 184 ? 122.895 130.936 140.435 1.00 47.61 ? 184 SER A C   1 
ATOM   728  O O   . SER A 1 184 ? 123.675 131.586 139.731 1.00 46.03 ? 184 SER A O   1 
ATOM   729  C CB  . SER A 1 184 ? 123.622 128.585 140.802 1.00 38.75 ? 184 SER A CB  1 
ATOM   730  O OG  . SER A 1 184 ? 124.568 127.803 141.507 1.00 43.12 ? 184 SER A OG  1 
ATOM   731  N N   . ARG A 1 185 ? 121.570 131.055 140.331 1.00 49.38 ? 185 ARG A N   1 
ATOM   732  C CA  . ARG A 1 185 ? 120.995 131.999 139.380 1.00 43.31 ? 185 ARG A CA  1 
ATOM   733  C C   . ARG A 1 185 ? 121.348 133.434 139.750 1.00 40.14 ? 185 ARG A C   1 
ATOM   734  O O   . ARG A 1 185 ? 121.714 134.230 138.878 1.00 45.03 ? 185 ARG A O   1 
ATOM   735  C CB  . ARG A 1 185 ? 119.470 131.824 139.313 1.00 43.19 ? 185 ARG A CB  1 
ATOM   736  N N   . PHE A 1 186 ? 121.259 133.778 141.035 1.00 46.61 ? 186 PHE A N   1 
ATOM   737  C CA  . PHE A 1 186 ? 121.534 135.136 141.506 1.00 53.53 ? 186 PHE A CA  1 
ATOM   738  C C   . PHE A 1 186 ? 122.958 135.208 142.062 1.00 53.28 ? 186 PHE A C   1 
ATOM   739  O O   . PHE A 1 186 ? 123.204 135.399 143.253 1.00 51.98 ? 186 PHE A O   1 
ATOM   740  C CB  . PHE A 1 186 ? 120.485 135.557 142.536 1.00 53.87 ? 186 PHE A CB  1 
ATOM   741  C CG  . PHE A 1 186 ? 119.434 136.480 141.986 1.00 57.92 ? 186 PHE A CG  1 
ATOM   742  C CD1 . PHE A 1 186 ? 118.655 136.103 140.905 1.00 54.25 ? 186 PHE A CD1 1 
ATOM   743  C CD2 . PHE A 1 186 ? 119.230 137.727 142.549 1.00 51.92 ? 186 PHE A CD2 1 
ATOM   744  C CE1 . PHE A 1 186 ? 117.691 136.953 140.400 1.00 54.20 ? 186 PHE A CE1 1 
ATOM   745  C CE2 . PHE A 1 186 ? 118.269 138.580 142.049 1.00 50.30 ? 186 PHE A CE2 1 
ATOM   746  C CZ  . PHE A 1 186 ? 117.498 138.194 140.973 1.00 52.58 ? 186 PHE A CZ  1 
ATOM   747  N N   . ASN A 1 187 ? 123.916 135.019 141.155 1.00 57.51 ? 187 ASN A N   1 
ATOM   748  C CA  . ASN A 1 187 ? 125.329 135.199 141.482 1.00 53.45 ? 187 ASN A CA  1 
ATOM   749  C C   . ASN A 1 187 ? 126.066 135.459 140.171 1.00 58.47 ? 187 ASN A C   1 
ATOM   750  O O   . ASN A 1 187 ? 126.383 134.513 139.443 1.00 64.91 ? 187 ASN A O   1 
ATOM   751  C CB  . ASN A 1 187 ? 125.886 133.982 142.206 1.00 48.73 ? 187 ASN A CB  1 
ATOM   752  N N   . SER A 1 188 ? 126.322 136.757 139.914 1.00 62.34 ? 188 SER A N   1 
ATOM   753  C CA  . SER A 1 188 ? 126.961 137.232 138.658 1.00 67.84 ? 188 SER A CA  1 
ATOM   754  C C   . SER A 1 188 ? 128.286 137.934 138.967 1.00 70.07 ? 188 SER A C   1 
ATOM   755  O O   . SER A 1 188 ? 128.612 138.904 138.245 1.00 68.24 ? 188 SER A O   1 
ATOM   756  C CB  . SER A 1 188 ? 126.047 138.222 138.018 1.00 68.35 ? 188 SER A CB  1 
ATOM   757  O OG  . SER A 1 188 ? 126.597 138.730 136.810 1.00 69.12 ? 188 SER A OG  1 
ATOM   758  N N   . ARG A 1 189 ? 128.993 137.501 140.006 1.00 71.20 ? 189 ARG A N   1 
ATOM   759  C CA  . ARG A 1 189 ? 130.262 138.087 140.431 1.00 66.77 ? 189 ARG A CA  1 
ATOM   760  C C   . ARG A 1 189 ? 130.126 139.531 140.905 1.00 67.25 ? 189 ARG A C   1 
ATOM   761  O O   . ARG A 1 189 ? 131.143 140.188 141.155 1.00 67.27 ? 189 ARG A O   1 
ATOM   762  C CB  . ARG A 1 189 ? 131.316 138.012 139.319 1.00 65.40 ? 189 ARG A CB  1 
ATOM   763  N N   . THR A 1 190 ? 128.898 140.046 141.033 1.00 64.21 ? 190 THR A N   1 
ATOM   764  C CA  . THR A 1 190 ? 128.649 141.341 141.646 1.00 63.84 ? 190 THR A CA  1 
ATOM   765  C C   . THR A 1 190 ? 128.261 141.226 143.108 1.00 63.70 ? 190 THR A C   1 
ATOM   766  O O   . THR A 1 190 ? 128.476 142.177 143.865 1.00 65.27 ? 190 THR A O   1 
ATOM   767  C CB  . THR A 1 190 ? 127.531 142.088 140.902 1.00 65.13 ? 190 THR A CB  1 
ATOM   768  O OG1 . THR A 1 190 ? 126.265 141.495 141.214 1.00 65.74 ? 190 THR A OG1 1 
ATOM   769  C CG2 . THR A 1 190 ? 127.755 142.031 139.399 1.00 66.57 ? 190 THR A CG2 1 
ATOM   770  N N   . LYS A 1 191 ? 127.696 140.090 143.517 1.00 53.41 ? 191 LYS A N   1 
ATOM   771  C CA  . LYS A 1 191 ? 127.415 139.864 144.928 1.00 54.56 ? 191 LYS A CA  1 
ATOM   772  C C   . LYS A 1 191 ? 128.706 139.852 145.737 1.00 50.53 ? 191 LYS A C   1 
ATOM   773  O O   . LYS A 1 191 ? 128.779 140.449 146.817 1.00 49.76 ? 191 LYS A O   1 
ATOM   774  C CB  . LYS A 1 191 ? 126.655 138.547 145.091 1.00 55.13 ? 191 LYS A CB  1 
ATOM   775  C CG  . LYS A 1 191 ? 126.157 138.238 146.499 1.00 52.28 ? 191 LYS A CG  1 
ATOM   776  C CD  . LYS A 1 191 ? 126.231 136.744 146.808 1.00 47.13 ? 191 LYS A CD  1 
ATOM   777  C CE  . LYS A 1 191 ? 125.332 135.912 145.901 1.00 51.33 ? 191 LYS A CE  1 
ATOM   778  N NZ  . LYS A 1 191 ? 123.905 136.332 145.967 1.00 57.70 ? 191 LYS A NZ  1 
ATOM   779  N N   . ALA A 1 192 ? 129.741 139.184 145.221 1.00 50.81 ? 192 ALA A N   1 
ATOM   780  C CA  . ALA A 1 192 ? 131.001 139.089 145.949 1.00 50.86 ? 192 ALA A CA  1 
ATOM   781  C C   . ALA A 1 192 ? 131.611 140.464 146.171 1.00 48.16 ? 192 ALA A C   1 
ATOM   782  O O   . ALA A 1 192 ? 132.189 140.731 147.230 1.00 48.60 ? 192 ALA A O   1 
ATOM   783  C CB  . ALA A 1 192 ? 131.977 138.188 145.197 1.00 57.35 ? 192 ALA A CB  1 
ATOM   784  N N   . PHE A 1 193 ? 131.502 141.349 145.177 1.00 58.37 ? 193 PHE A N   1 
ATOM   785  C CA  . PHE A 1 193 ? 131.937 142.728 145.372 1.00 60.66 ? 193 PHE A CA  1 
ATOM   786  C C   . PHE A 1 193 ? 130.953 143.505 146.234 1.00 56.11 ? 193 PHE A C   1 
ATOM   787  O O   . PHE A 1 193 ? 131.358 144.419 146.960 1.00 50.45 ? 193 PHE A O   1 
ATOM   788  C CB  . PHE A 1 193 ? 132.123 143.422 144.020 1.00 60.59 ? 193 PHE A CB  1 
ATOM   789  C CG  . PHE A 1 193 ? 133.507 143.274 143.443 1.00 62.12 ? 193 PHE A CG  1 
ATOM   790  C CD1 . PHE A 1 193 ? 134.608 143.831 144.078 1.00 60.67 ? 193 PHE A CD1 1 
ATOM   791  C CD2 . PHE A 1 193 ? 133.704 142.577 142.266 1.00 58.22 ? 193 PHE A CD2 1 
ATOM   792  C CE1 . PHE A 1 193 ? 135.873 143.692 143.549 1.00 59.58 ? 193 PHE A CE1 1 
ATOM   793  C CE2 . PHE A 1 193 ? 134.970 142.437 141.732 1.00 59.14 ? 193 PHE A CE2 1 
ATOM   794  C CZ  . PHE A 1 193 ? 136.054 142.996 142.374 1.00 61.52 ? 193 PHE A CZ  1 
ATOM   795  N N   . LEU A 1 194 ? 129.667 143.167 146.169 1.00 46.27 ? 194 LEU A N   1 
ATOM   796  C CA  . LEU A 1 194 ? 128.702 143.777 147.075 1.00 45.62 ? 194 LEU A CA  1 
ATOM   797  C C   . LEU A 1 194 ? 128.840 143.234 148.491 1.00 51.23 ? 194 LEU A C   1 
ATOM   798  O O   . LEU A 1 194 ? 128.451 143.912 149.448 1.00 50.65 ? 194 LEU A O   1 
ATOM   799  C CB  . LEU A 1 194 ? 127.281 143.551 146.562 1.00 49.25 ? 194 LEU A CB  1 
ATOM   800  C CG  . LEU A 1 194 ? 126.171 144.244 147.353 1.00 52.31 ? 194 LEU A CG  1 
ATOM   801  C CD1 . LEU A 1 194 ? 125.196 144.934 146.412 1.00 46.48 ? 194 LEU A CD1 1 
ATOM   802  C CD2 . LEU A 1 194 ? 125.443 143.250 148.247 1.00 50.95 ? 194 LEU A CD2 1 
ATOM   803  N N   . LYS A 1 195 ? 129.366 142.016 148.644 1.00 55.19 ? 195 LYS A N   1 
ATOM   804  C CA  . LYS A 1 195 ? 129.602 141.458 149.971 1.00 45.30 ? 195 LYS A CA  1 
ATOM   805  C C   . LYS A 1 195 ? 130.826 142.066 150.640 1.00 41.57 ? 195 LYS A C   1 
ATOM   806  O O   . LYS A 1 195 ? 130.796 142.325 151.846 1.00 42.41 ? 195 LYS A O   1 
ATOM   807  C CB  . LYS A 1 195 ? 129.764 139.941 149.878 1.00 45.39 ? 195 LYS A CB  1 
ATOM   808  C CG  . LYS A 1 195 ? 129.245 139.176 151.088 1.00 48.99 ? 195 LYS A CG  1 
ATOM   809  C CD  . LYS A 1 195 ? 128.975 137.708 150.779 1.00 48.90 ? 195 LYS A CD  1 
ATOM   810  C CE  . LYS A 1 195 ? 127.680 137.509 150.001 1.00 46.40 ? 195 LYS A CE  1 
ATOM   811  N NZ  . LYS A 1 195 ? 126.490 137.591 150.893 1.00 43.83 ? 195 LYS A NZ  1 
ATOM   812  N N   . ILE A 1 196 ? 131.903 142.297 149.886 1.00 42.69 ? 196 ILE A N   1 
ATOM   813  C CA  . ILE A 1 196 ? 133.083 142.944 150.452 1.00 40.16 ? 196 ILE A CA  1 
ATOM   814  C C   . ILE A 1 196 ? 132.742 144.356 150.908 1.00 46.40 ? 196 ILE A C   1 
ATOM   815  O O   . ILE A 1 196 ? 133.327 144.871 151.867 1.00 48.57 ? 196 ILE A O   1 
ATOM   816  C CB  . ILE A 1 196 ? 134.237 142.933 149.432 1.00 45.19 ? 196 ILE A CB  1 
ATOM   817  C CG1 . ILE A 1 196 ? 134.856 141.538 149.352 1.00 49.75 ? 196 ILE A CG1 1 
ATOM   818  C CG2 . ILE A 1 196 ? 135.319 143.946 149.806 1.00 43.14 ? 196 ILE A CG2 1 
ATOM   819  C CD1 . ILE A 1 196 ? 135.649 141.284 148.088 1.00 50.84 ? 196 ILE A CD1 1 
ATOM   820  N N   . ILE A 1 197 ? 131.814 145.014 150.214 1.00 45.11 ? 197 ILE A N   1 
ATOM   821  C CA  . ILE A 1 197 ? 131.380 146.341 150.636 1.00 40.80 ? 197 ILE A CA  1 
ATOM   822  C C   . ILE A 1 197 ? 130.667 146.258 151.980 1.00 36.45 ? 197 ILE A C   1 
ATOM   823  O O   . ILE A 1 197 ? 130.905 147.078 152.874 1.00 39.17 ? 197 ILE A O   1 
ATOM   824  C CB  . ILE A 1 197 ? 130.503 146.977 149.535 1.00 41.73 ? 197 ILE A CB  1 
ATOM   825  C CG1 . ILE A 1 197 ? 131.417 147.671 148.514 1.00 45.35 ? 197 ILE A CG1 1 
ATOM   826  C CG2 . ILE A 1 197 ? 129.452 147.962 150.127 1.00 42.32 ? 197 ILE A CG2 1 
ATOM   827  C CD1 . ILE A 1 197 ? 130.717 148.290 147.316 1.00 46.46 ? 197 ILE A CD1 1 
ATOM   828  N N   . ALA A 1 198 ? 129.788 145.269 152.147 1.00 35.26 ? 198 ALA A N   1 
ATOM   829  C CA  . ALA A 1 198 ? 128.964 145.205 153.350 1.00 37.71 ? 198 ALA A CA  1 
ATOM   830  C C   . ALA A 1 198 ? 129.793 144.885 154.588 1.00 41.72 ? 198 ALA A C   1 
ATOM   831  O O   . ALA A 1 198 ? 129.589 145.489 155.646 1.00 40.27 ? 198 ALA A O   1 
ATOM   832  C CB  . ALA A 1 198 ? 127.852 144.174 153.168 1.00 39.91 ? 198 ALA A CB  1 
ATOM   833  N N   . VAL A 1 199 ? 130.731 143.938 154.487 1.00 43.12 ? 199 VAL A N   1 
ATOM   834  C CA  . VAL A 1 199 ? 131.523 143.556 155.657 1.00 38.39 ? 199 VAL A CA  1 
ATOM   835  C C   . VAL A 1 199 ? 132.611 144.559 155.998 1.00 38.09 ? 199 VAL A C   1 
ATOM   836  O O   . VAL A 1 199 ? 133.219 144.441 157.067 1.00 37.72 ? 199 VAL A O   1 
ATOM   837  C CB  . VAL A 1 199 ? 132.180 142.175 155.479 1.00 30.26 ? 199 VAL A CB  1 
ATOM   838  C CG1 . VAL A 1 199 ? 131.144 141.151 155.049 1.00 33.93 ? 199 VAL A CG1 1 
ATOM   839  C CG2 . VAL A 1 199 ? 133.332 142.237 154.490 1.00 32.44 ? 199 VAL A CG2 1 
ATOM   840  N N   . TRP A 1 200 ? 132.887 145.528 155.119 1.00 36.82 ? 200 TRP A N   1 
ATOM   841  C CA  . TRP A 1 200 ? 133.829 146.605 155.401 1.00 38.81 ? 200 TRP A CA  1 
ATOM   842  C C   . TRP A 1 200 ? 133.147 147.933 155.694 1.00 48.45 ? 200 TRP A C   1 
ATOM   843  O O   . TRP A 1 200 ? 133.792 148.832 156.243 1.00 45.60 ? 200 TRP A O   1 
ATOM   844  C CB  . TRP A 1 200 ? 134.793 146.787 154.227 1.00 31.24 ? 200 TRP A CB  1 
ATOM   845  C CG  . TRP A 1 200 ? 135.936 145.836 154.258 1.00 32.32 ? 200 TRP A CG  1 
ATOM   846  C CD1 . TRP A 1 200 ? 136.099 144.738 153.476 1.00 41.85 ? 200 TRP A CD1 1 
ATOM   847  C CD2 . TRP A 1 200 ? 137.077 145.890 155.118 1.00 31.45 ? 200 TRP A CD2 1 
ATOM   848  N NE1 . TRP A 1 200 ? 137.273 144.102 153.790 1.00 39.57 ? 200 TRP A NE1 1 
ATOM   849  C CE2 . TRP A 1 200 ? 137.892 144.791 154.797 1.00 35.45 ? 200 TRP A CE2 1 
ATOM   850  C CE3 . TRP A 1 200 ? 137.490 146.761 156.127 1.00 37.15 ? 200 TRP A CE3 1 
ATOM   851  C CZ2 . TRP A 1 200 ? 139.094 144.539 155.447 1.00 34.66 ? 200 TRP A CZ2 1 
ATOM   852  C CZ3 . TRP A 1 200 ? 138.685 146.508 156.772 1.00 39.74 ? 200 TRP A CZ3 1 
ATOM   853  C CH2 . TRP A 1 200 ? 139.471 145.407 156.431 1.00 35.22 ? 200 TRP A CH2 1 
ATOM   854  N N   . THR A 1 201 ? 131.874 148.088 155.326 1.00 42.04 ? 201 THR A N   1 
ATOM   855  C CA  . THR A 1 201 ? 131.125 149.265 155.749 1.00 34.37 ? 201 THR A CA  1 
ATOM   856  C C   . THR A 1 201 ? 130.750 149.170 157.222 1.00 46.78 ? 201 THR A C   1 
ATOM   857  O O   . THR A 1 201 ? 130.807 150.168 157.948 1.00 52.18 ? 201 THR A O   1 
ATOM   858  C CB  . THR A 1 201 ? 129.871 149.429 154.890 1.00 32.75 ? 201 THR A CB  1 
ATOM   859  O OG1 . THR A 1 201 ? 130.242 149.524 153.511 1.00 42.42 ? 201 THR A OG1 1 
ATOM   860  C CG2 . THR A 1 201 ? 129.097 150.676 155.287 1.00 34.39 ? 201 THR A CG2 1 
ATOM   861  N N   . ILE A 1 202 ? 130.359 147.981 157.679 1.00 43.61 ? 202 ILE A N   1 
ATOM   862  C CA  . ILE A 1 202 ? 129.977 147.817 159.077 1.00 42.10 ? 202 ILE A CA  1 
ATOM   863  C C   . ILE A 1 202 ? 131.215 147.772 159.966 1.00 35.32 ? 202 ILE A C   1 
ATOM   864  O O   . ILE A 1 202 ? 131.193 148.255 161.103 1.00 33.77 ? 202 ILE A O   1 
ATOM   865  C CB  . ILE A 1 202 ? 129.108 146.556 159.242 1.00 41.37 ? 202 ILE A CB  1 
ATOM   866  C CG1 . ILE A 1 202 ? 127.866 146.603 158.334 1.00 40.74 ? 202 ILE A CG1 1 
ATOM   867  C CG2 . ILE A 1 202 ? 128.664 146.422 160.690 1.00 42.74 ? 202 ILE A CG2 1 
ATOM   868  C CD1 . ILE A 1 202 ? 127.106 147.920 158.307 1.00 47.44 ? 202 ILE A CD1 1 
ATOM   869  N N   . SER A 1 203 ? 132.301 147.188 159.453 1.00 35.95 ? 203 SER A N   1 
ATOM   870  C CA  . SER A 1 203 ? 133.565 147.140 160.234 1.00 43.20 ? 203 SER A CA  1 
ATOM   871  C C   . SER A 1 203 ? 134.067 148.570 160.472 1.00 42.39 ? 203 SER A C   1 
ATOM   872  O O   . SER A 1 203 ? 134.452 148.880 161.621 1.00 46.15 ? 203 SER A O   1 
ATOM   873  C CB  . SER A 1 203 ? 134.608 146.314 159.535 1.00 42.80 ? 203 SER A CB  1 
ATOM   874  O OG  . SER A 1 203 ? 135.089 146.982 158.377 1.00 48.22 ? 203 SER A OG  1 
ATOM   875  N N   . VAL A 1 204 ? 134.057 149.402 159.427 1.00 43.12 ? 204 VAL A N   1 
ATOM   876  C CA  . VAL A 1 204 ? 134.527 150.780 159.543 1.00 52.17 ? 204 VAL A CA  1 
ATOM   877  C C   . VAL A 1 204 ? 133.487 151.709 160.152 1.00 54.53 ? 204 VAL A C   1 
ATOM   878  O O   . VAL A 1 204 ? 133.850 152.795 160.628 1.00 54.03 ? 204 VAL A O   1 
ATOM   879  C CB  . VAL A 1 204 ? 134.974 151.320 158.169 1.00 47.40 ? 204 VAL A CB  1 
ATOM   880  C CG1 . VAL A 1 204 ? 133.783 151.774 157.332 1.00 48.25 ? 204 VAL A CG1 1 
ATOM   881  C CG2 . VAL A 1 204 ? 135.964 152.461 158.348 1.00 48.65 ? 204 VAL A CG2 1 
ATOM   882  N N   . GLY A 1 205 ? 132.211 151.327 160.154 1.00 50.90 ? 205 GLY A N   1 
ATOM   883  C CA  . GLY A 1 205 ? 131.185 152.131 160.785 1.00 47.11 ? 205 GLY A CA  1 
ATOM   884  C C   . GLY A 1 205 ? 131.030 151.920 162.271 1.00 50.42 ? 205 GLY A C   1 
ATOM   885  O O   . GLY A 1 205 ? 130.548 152.818 162.965 1.00 52.62 ? 205 GLY A O   1 
ATOM   886  N N   . ILE A 1 206 ? 131.436 150.762 162.784 1.00 54.08 ? 206 ILE A N   1 
ATOM   887  C CA  . ILE A 1 206 ? 131.339 150.457 164.206 1.00 52.18 ? 206 ILE A CA  1 
ATOM   888  C C   . ILE A 1 206 ? 132.541 150.992 164.972 1.00 51.34 ? 206 ILE A C   1 
ATOM   889  O O   . ILE A 1 206 ? 132.422 151.340 166.147 1.00 56.34 ? 206 ILE A O   1 
ATOM   890  C CB  . ILE A 1 206 ? 131.176 148.932 164.406 1.00 49.44 ? 206 ILE A CB  1 
ATOM   891  C CG1 . ILE A 1 206 ? 129.731 148.525 164.109 1.00 49.18 ? 206 ILE A CG1 1 
ATOM   892  C CG2 . ILE A 1 206 ? 131.555 148.505 165.839 1.00 45.41 ? 206 ILE A CG2 1 
ATOM   893  C CD1 . ILE A 1 206 ? 129.522 147.036 163.927 1.00 49.66 ? 206 ILE A CD1 1 
ATOM   894  N N   . SER A 1 207 ? 133.701 151.045 164.327 1.00 48.06 ? 207 SER A N   1 
ATOM   895  C CA  . SER A 1 207 ? 134.927 151.539 164.935 1.00 49.36 ? 207 SER A CA  1 
ATOM   896  C C   . SER A 1 207 ? 135.199 153.008 164.622 1.00 55.30 ? 207 SER A C   1 
ATOM   897  O O   . SER A 1 207 ? 136.274 153.510 164.966 1.00 55.03 ? 207 SER A O   1 
ATOM   898  C CB  . SER A 1 207 ? 136.103 150.674 164.484 1.00 51.03 ? 207 SER A CB  1 
ATOM   899  O OG  . SER A 1 207 ? 136.701 151.190 163.317 1.00 52.65 ? 207 SER A OG  1 
ATOM   900  N N   . MET A 1 208 ? 134.267 153.699 163.964 1.00 64.26 ? 208 MET A N   1 
ATOM   901  C CA  . MET A 1 208 ? 134.367 155.130 163.689 1.00 64.85 ? 208 MET A CA  1 
ATOM   902  C C   . MET A 1 208 ? 134.178 156.021 164.919 1.00 62.63 ? 208 MET A C   1 
ATOM   903  O O   . MET A 1 208 ? 134.673 157.153 164.916 1.00 54.73 ? 208 MET A O   1 
ATOM   904  C CB  . MET A 1 208 ? 133.346 155.528 162.618 1.00 60.25 ? 208 MET A CB  1 
ATOM   905  C CG  . MET A 1 208 ? 133.427 156.981 162.142 1.00 57.96 ? 208 MET A CG  1 
ATOM   906  S SD  . MET A 1 208 ? 135.075 157.590 161.720 1.00 78.78 ? 208 MET A SD  1 
ATOM   907  C CE  . MET A 1 208 ? 135.688 156.269 160.676 1.00 62.62 ? 208 MET A CE  1 
ATOM   908  N N   . PRO A 1 209 ? 133.430 155.615 165.953 1.00 58.79 ? 209 PRO A N   1 
ATOM   909  C CA  . PRO A 1 209 ? 133.415 156.419 167.185 1.00 54.62 ? 209 PRO A CA  1 
ATOM   910  C C   . PRO A 1 209 ? 134.756 156.530 167.891 1.00 54.63 ? 209 PRO A C   1 
ATOM   911  O O   . PRO A 1 209 ? 134.916 157.442 168.710 1.00 58.41 ? 209 PRO A O   1 
ATOM   912  C CB  . PRO A 1 209 ? 132.396 155.687 168.061 1.00 55.77 ? 209 PRO A CB  1 
ATOM   913  C CG  . PRO A 1 209 ? 131.446 155.139 167.100 1.00 53.31 ? 209 PRO A CG  1 
ATOM   914  C CD  . PRO A 1 209 ? 132.276 154.696 165.932 1.00 52.98 ? 209 PRO A CD  1 
ATOM   915  N N   . ILE A 1 210 ? 135.714 155.646 167.629 1.00 56.83 ? 210 ILE A N   1 
ATOM   916  C CA  . ILE A 1 210 ? 136.941 155.615 168.425 1.00 59.81 ? 210 ILE A CA  1 
ATOM   917  C C   . ILE A 1 210 ? 137.783 156.865 168.171 1.00 56.43 ? 210 ILE A C   1 
ATOM   918  O O   . ILE A 1 210 ? 138.120 157.554 169.144 1.00 55.85 ? 210 ILE A O   1 
ATOM   919  C CB  . ILE A 1 210 ? 137.743 154.322 168.185 1.00 61.14 ? 210 ILE A CB  1 
ATOM   920  C CG1 . ILE A 1 210 ? 136.964 153.122 168.733 1.00 60.58 ? 210 ILE A CG1 1 
ATOM   921  C CG2 . ILE A 1 210 ? 139.120 154.427 168.848 1.00 60.97 ? 210 ILE A CG2 1 
ATOM   922  C CD1 . ILE A 1 210 ? 137.520 151.777 168.338 1.00 55.31 ? 210 ILE A CD1 1 
ATOM   923  N N   . PRO A 1 211 ? 138.146 157.218 166.936 1.00 61.51 ? 211 PRO A N   1 
ATOM   924  C CA  . PRO A 1 211 ? 138.982 158.415 166.735 1.00 64.68 ? 211 PRO A CA  1 
ATOM   925  C C   . PRO A 1 211 ? 138.223 159.719 166.513 1.00 68.04 ? 211 PRO A C   1 
ATOM   926  O O   . PRO A 1 211 ? 138.861 160.777 166.560 1.00 67.98 ? 211 PRO A O   1 
ATOM   927  C CB  . PRO A 1 211 ? 139.784 158.041 165.481 1.00 62.76 ? 211 PRO A CB  1 
ATOM   928  C CG  . PRO A 1 211 ? 138.991 156.962 164.787 1.00 66.16 ? 211 PRO A CG  1 
ATOM   929  C CD  . PRO A 1 211 ? 137.797 156.640 165.629 1.00 62.08 ? 211 PRO A CD  1 
ATOM   930  N N   . VAL A 1 212 ? 136.908 159.684 166.282 1.00 70.72 ? 212 VAL A N   1 
ATOM   931  C CA  . VAL A 1 212 ? 136.124 160.906 166.122 1.00 66.33 ? 212 VAL A CA  1 
ATOM   932  C C   . VAL A 1 212 ? 135.598 161.435 167.452 1.00 66.03 ? 212 VAL A C   1 
ATOM   933  O O   . VAL A 1 212 ? 135.365 162.647 167.572 1.00 65.72 ? 212 VAL A O   1 
ATOM   934  C CB  . VAL A 1 212 ? 134.951 160.695 165.142 1.00 61.45 ? 212 VAL A CB  1 
ATOM   935  C CG1 . VAL A 1 212 ? 133.838 159.890 165.789 1.00 61.26 ? 212 VAL A CG1 1 
ATOM   936  C CG2 . VAL A 1 212 ? 134.421 162.036 164.649 1.00 62.35 ? 212 VAL A CG2 1 
ATOM   937  N N   . PHE A 1 213 ? 135.385 160.568 168.441 1.00 63.65 ? 213 PHE A N   1 
ATOM   938  C CA  . PHE A 1 213 ? 135.002 160.973 169.795 1.00 60.94 ? 213 PHE A CA  1 
ATOM   939  C C   . PHE A 1 213 ? 135.758 160.032 170.726 1.00 64.82 ? 213 PHE A C   1 
ATOM   940  O O   . PHE A 1 213 ? 135.279 158.942 171.048 1.00 71.06 ? 213 PHE A O   1 
ATOM   941  C CB  . PHE A 1 213 ? 133.497 160.902 170.007 1.00 61.40 ? 213 PHE A CB  1 
ATOM   942  N N   . GLY A 1 214 ? 136.936 160.467 171.160 1.00 64.34 ? 214 GLY A N   1 
ATOM   943  C CA  . GLY A 1 214 ? 137.845 159.617 171.900 1.00 65.04 ? 214 GLY A CA  1 
ATOM   944  C C   . GLY A 1 214 ? 139.291 159.913 171.566 1.00 63.91 ? 214 GLY A C   1 
ATOM   945  O O   . GLY A 1 214 ? 140.191 159.575 172.338 1.00 65.35 ? 214 GLY A O   1 
ATOM   946  N N   . LEU A 1 215 ? 139.528 160.534 170.410 1.00 67.81 ? 215 LEU A N   1 
ATOM   947  C CA  . LEU A 1 215 ? 140.831 161.110 170.106 1.00 71.63 ? 215 LEU A CA  1 
ATOM   948  C C   . LEU A 1 215 ? 140.975 162.515 170.667 1.00 74.01 ? 215 LEU A C   1 
ATOM   949  O O   . LEU A 1 215 ? 142.090 162.932 170.999 1.00 73.92 ? 215 LEU A O   1 
ATOM   950  C CB  . LEU A 1 215 ? 141.061 161.142 168.594 1.00 68.19 ? 215 LEU A CB  1 
ATOM   951  C CG  . LEU A 1 215 ? 142.484 161.470 168.145 1.00 68.74 ? 215 LEU A CG  1 
ATOM   952  C CD1 . LEU A 1 215 ? 142.927 160.520 167.049 1.00 67.45 ? 215 LEU A CD1 1 
ATOM   953  C CD2 . LEU A 1 215 ? 142.579 162.907 167.668 1.00 70.43 ? 215 LEU A CD2 1 
ATOM   954  N N   . GLN A 1 216 ? 139.870 163.256 170.775 1.00 75.41 ? 216 GLN A N   1 
ATOM   955  C CA  . GLN A 1 216 ? 139.922 164.560 171.428 1.00 75.23 ? 216 GLN A CA  1 
ATOM   956  C C   . GLN A 1 216 ? 140.032 164.403 172.939 1.00 72.44 ? 216 GLN A C   1 
ATOM   957  O O   . GLN A 1 216 ? 140.791 165.128 173.592 1.00 72.73 ? 216 GLN A O   1 
ATOM   958  C CB  . GLN A 1 216 ? 138.691 165.395 171.065 1.00 75.47 ? 216 GLN A CB  1 
ATOM   959  C CG  . GLN A 1 216 ? 138.232 165.274 169.614 1.00 75.46 ? 216 GLN A CG  1 
ATOM   960  C CD  . GLN A 1 216 ? 137.235 166.348 169.220 1.00 75.37 ? 216 GLN A CD  1 
ATOM   961  O OE1 . GLN A 1 216 ? 137.256 167.461 169.747 1.00 72.81 ? 216 GLN A OE1 1 
ATOM   962  N NE2 . GLN A 1 216 ? 136.351 166.017 168.286 1.00 74.10 ? 216 GLN A NE2 1 
ATOM   963  N N   . ASP A 1 217 ? 139.287 163.457 173.507 1.00 75.87 ? 217 ASP A N   1 
ATOM   964  C CA  . ASP A 1 217 ? 139.358 163.149 174.928 1.00 79.78 ? 217 ASP A CA  1 
ATOM   965  C C   . ASP A 1 217 ? 140.432 162.096 175.159 1.00 79.77 ? 217 ASP A C   1 
ATOM   966  O O   . ASP A 1 217 ? 140.371 161.004 174.589 1.00 77.09 ? 217 ASP A O   1 
ATOM   967  C CB  . ASP A 1 217 ? 138.009 162.641 175.441 1.00 81.25 ? 217 ASP A CB  1 
ATOM   968  C CG  . ASP A 1 217 ? 137.034 163.762 175.755 1.00 81.54 ? 217 ASP A CG  1 
ATOM   969  O OD1 . ASP A 1 217 ? 137.364 164.943 175.517 1.00 78.00 ? 217 ASP A OD1 1 
ATOM   970  O OD2 . ASP A 1 217 ? 135.928 163.459 176.248 1.00 83.04 ? 217 ASP A OD2 1 
ATOM   971  N N   . ASP A 1 218 ? 141.410 162.424 176.002 1.00 73.39 ? 218 ASP A N   1 
ATOM   972  C CA  . ASP A 1 218 ? 142.514 161.525 176.310 1.00 69.53 ? 218 ASP A CA  1 
ATOM   973  C C   . ASP A 1 218 ? 142.221 160.637 177.514 1.00 72.50 ? 218 ASP A C   1 
ATOM   974  O O   . ASP A 1 218 ? 143.154 160.132 178.147 1.00 72.36 ? 218 ASP A O   1 
ATOM   975  C CB  . ASP A 1 218 ? 143.794 162.326 176.544 1.00 67.05 ? 218 ASP A CB  1 
ATOM   976  N N   . SER A 1 219 ? 140.938 160.448 177.856 1.00 74.52 ? 219 SER A N   1 
ATOM   977  C CA  . SER A 1 219 ? 140.569 159.572 178.963 1.00 70.59 ? 219 SER A CA  1 
ATOM   978  C C   . SER A 1 219 ? 139.320 158.736 178.696 1.00 69.52 ? 219 SER A C   1 
ATOM   979  O O   . SER A 1 219 ? 138.973 157.900 179.540 1.00 66.44 ? 219 SER A O   1 
ATOM   980  C CB  . SER A 1 219 ? 140.360 160.396 180.238 1.00 65.64 ? 219 SER A CB  1 
ATOM   981  N N   . LYS A 1 220 ? 138.640 158.914 177.559 1.00 67.10 ? 220 LYS A N   1 
ATOM   982  C CA  . LYS A 1 220 ? 137.405 158.178 177.306 1.00 65.17 ? 220 LYS A CA  1 
ATOM   983  C C   . LYS A 1 220 ? 137.708 156.865 176.601 1.00 63.91 ? 220 LYS A C   1 
ATOM   984  O O   . LYS A 1 220 ? 137.467 155.790 177.159 1.00 62.21 ? 220 LYS A O   1 
ATOM   985  C CB  . LYS A 1 220 ? 136.444 159.018 176.464 1.00 59.75 ? 220 LYS A CB  1 
ATOM   986  N N   . VAL A 1 221 ? 138.235 156.942 175.379 1.00 63.18 ? 221 VAL A N   1 
ATOM   987  C CA  . VAL A 1 221 ? 138.890 155.809 174.736 1.00 66.93 ? 221 VAL A CA  1 
ATOM   988  C C   . VAL A 1 221 ? 140.382 156.067 174.833 1.00 63.50 ? 221 VAL A C   1 
ATOM   989  O O   . VAL A 1 221 ? 140.988 156.610 173.903 1.00 69.06 ? 221 VAL A O   1 
ATOM   990  C CB  . VAL A 1 221 ? 138.450 155.641 173.270 1.00 66.07 ? 221 VAL A CB  1 
ATOM   991  C CG1 . VAL A 1 221 ? 139.191 154.479 172.626 1.00 62.28 ? 221 VAL A CG1 1 
ATOM   992  C CG2 . VAL A 1 221 ? 136.940 155.443 173.174 1.00 61.66 ? 221 VAL A CG2 1 
ATOM   993  N N   . PHE A 1 222 ? 140.992 155.675 175.944 1.00 49.22 ? 222 PHE A N   1 
ATOM   994  C CA  . PHE A 1 222 ? 142.357 156.110 176.185 1.00 49.84 ? 222 PHE A CA  1 
ATOM   995  C C   . PHE A 1 222 ? 142.977 155.420 177.386 1.00 54.11 ? 222 PHE A C   1 
ATOM   996  O O   . PHE A 1 222 ? 142.397 154.492 177.957 1.00 59.49 ? 222 PHE A O   1 
ATOM   997  C CB  . PHE A 1 222 ? 142.392 157.624 176.375 1.00 56.87 ? 222 PHE A CB  1 
ATOM   998  N N   . LYS A 1 223 ? 144.155 155.887 177.779 1.00 58.56 ? 223 LYS A N   1 
ATOM   999  C CA  . LYS A 1 223 ? 144.954 155.171 178.755 1.00 61.09 ? 223 LYS A CA  1 
ATOM   1000 C C   . LYS A 1 223 ? 144.397 155.326 180.163 1.00 60.83 ? 223 LYS A C   1 
ATOM   1001 O O   . LYS A 1 223 ? 143.929 156.397 180.557 1.00 54.47 ? 223 LYS A O   1 
ATOM   1002 C CB  . LYS A 1 223 ? 146.398 155.675 178.708 1.00 60.52 ? 223 LYS A CB  1 
ATOM   1003 N N   . GLU A 1 224 ? 144.437 154.225 180.911 1.00 70.06 ? 224 GLU A N   1 
ATOM   1004 C CA  . GLU A 1 224 ? 144.450 154.242 182.365 1.00 72.37 ? 224 GLU A CA  1 
ATOM   1005 C C   . GLU A 1 224 ? 145.878 154.169 182.891 1.00 70.09 ? 224 GLU A C   1 
ATOM   1006 O O   . GLU A 1 224 ? 146.111 153.641 183.983 1.00 68.19 ? 224 GLU A O   1 
ATOM   1007 C CB  . GLU A 1 224 ? 143.622 153.079 182.916 1.00 71.39 ? 224 GLU A CB  1 
ATOM   1008 C CG  . GLU A 1 224 ? 142.198 153.000 182.376 1.00 69.72 ? 224 GLU A CG  1 
ATOM   1009 C CD  . GLU A 1 224 ? 141.413 154.279 182.577 1.00 70.73 ? 224 GLU A CD  1 
ATOM   1010 O OE1 . GLU A 1 224 ? 140.598 154.335 183.521 1.00 69.45 ? 224 GLU A OE1 1 
ATOM   1011 O OE2 . GLU A 1 224 ? 141.614 155.228 181.792 1.00 72.32 ? 224 GLU A OE2 1 
ATOM   1012 N N   . GLY A 1 225 ? 146.832 154.697 182.126 1.00 72.58 ? 225 GLY A N   1 
ATOM   1013 C CA  . GLY A 1 225 ? 148.231 154.365 182.261 1.00 69.98 ? 225 GLY A CA  1 
ATOM   1014 C C   . GLY A 1 225 ? 148.681 153.198 181.405 1.00 71.62 ? 225 GLY A C   1 
ATOM   1015 O O   . GLY A 1 225 ? 149.877 152.880 181.408 1.00 70.88 ? 225 GLY A O   1 
ATOM   1016 N N   . SER A 1 226 ? 147.764 152.564 180.657 1.00 69.16 ? 226 SER A N   1 
ATOM   1017 C CA  . SER A 1 226 ? 148.051 151.334 179.926 1.00 66.45 ? 226 SER A CA  1 
ATOM   1018 C C   . SER A 1 226 ? 147.438 151.276 178.530 1.00 63.78 ? 226 SER A C   1 
ATOM   1019 O O   . SER A 1 226 ? 147.572 150.242 177.865 1.00 64.78 ? 226 SER A O   1 
ATOM   1020 C CB  . SER A 1 226 ? 147.561 150.121 180.734 1.00 67.72 ? 226 SER A CB  1 
ATOM   1021 O OG  . SER A 1 226 ? 148.532 149.722 181.682 1.00 65.94 ? 226 SER A OG  1 
ATOM   1022 N N   . CYS A 1 227 ? 146.793 152.343 178.060 1.00 56.56 ? 227 CYS A N   1 
ATOM   1023 C CA  . CYS A 1 227 ? 146.149 152.375 176.749 1.00 57.49 ? 227 CYS A CA  1 
ATOM   1024 C C   . CYS A 1 227 ? 145.087 151.292 176.607 1.00 57.74 ? 227 CYS A C   1 
ATOM   1025 O O   . CYS A 1 227 ? 145.216 150.397 175.767 1.00 59.14 ? 227 CYS A O   1 
ATOM   1026 C CB  . CYS A 1 227 ? 147.185 152.234 175.631 1.00 59.88 ? 227 CYS A CB  1 
ATOM   1027 S SG  . CYS A 1 227 ? 146.505 152.496 173.975 1.00 61.33 ? 227 CYS A SG  1 
ATOM   1028 N N   . LEU A 1 228 ? 144.040 151.365 177.421 1.00 58.16 ? 228 LEU A N   1 
ATOM   1029 C CA  . LEU A 1 228 ? 142.892 150.475 177.346 1.00 52.58 ? 228 LEU A CA  1 
ATOM   1030 C C   . LEU A 1 228 ? 141.724 151.220 176.710 1.00 57.51 ? 228 LEU A C   1 
ATOM   1031 O O   . LEU A 1 228 ? 141.832 152.394 176.348 1.00 64.29 ? 228 LEU A O   1 
ATOM   1032 C CB  . LEU A 1 228 ? 142.523 149.951 178.736 1.00 55.82 ? 228 LEU A CB  1 
ATOM   1033 C CG  . LEU A 1 228 ? 143.608 149.179 179.489 1.00 61.23 ? 228 LEU A CG  1 
ATOM   1034 C CD1 . LEU A 1 228 ? 143.403 149.293 180.990 1.00 60.06 ? 228 LEU A CD1 1 
ATOM   1035 C CD2 . LEU A 1 228 ? 143.624 147.722 179.059 1.00 61.04 ? 228 LEU A CD2 1 
ATOM   1036 N N   . LEU A 1 229 ? 140.599 150.522 176.575 1.00 60.47 ? 229 LEU A N   1 
ATOM   1037 C CA  . LEU A 1 229 ? 139.363 151.092 176.038 1.00 58.09 ? 229 LEU A CA  1 
ATOM   1038 C C   . LEU A 1 229 ? 138.422 151.319 177.219 1.00 58.44 ? 229 LEU A C   1 
ATOM   1039 O O   . LEU A 1 229 ? 137.663 150.429 177.609 1.00 50.77 ? 229 LEU A O   1 
ATOM   1040 C CB  . LEU A 1 229 ? 138.770 150.169 174.977 1.00 52.23 ? 229 LEU A CB  1 
ATOM   1041 C CG  . LEU A 1 229 ? 138.033 150.842 173.819 1.00 51.84 ? 229 LEU A CG  1 
ATOM   1042 C CD1 . LEU A 1 229 ? 137.523 149.803 172.841 1.00 48.95 ? 229 LEU A CD1 1 
ATOM   1043 C CD2 . LEU A 1 229 ? 136.884 151.690 174.328 1.00 56.03 ? 229 LEU A CD2 1 
ATOM   1044 N N   . ALA A 1 230 ? 138.481 152.519 177.792 1.00 61.98 ? 230 ALA A N   1 
ATOM   1045 C CA  . ALA A 1 230 ? 137.805 152.826 179.046 1.00 60.17 ? 230 ALA A CA  1 
ATOM   1046 C C   . ALA A 1 230 ? 136.385 153.350 178.867 1.00 61.91 ? 230 ALA A C   1 
ATOM   1047 O O   . ALA A 1 230 ? 135.745 153.699 179.863 1.00 58.73 ? 230 ALA A O   1 
ATOM   1048 C CB  . ALA A 1 230 ? 138.624 153.846 179.841 1.00 58.72 ? 230 ALA A CB  1 
ATOM   1049 N N   . ASP A 1 231 ? 135.876 153.424 177.640 1.00 61.83 ? 231 ASP A N   1 
ATOM   1050 C CA  . ASP A 1 231 ? 134.485 153.802 177.415 1.00 57.48 ? 231 ASP A CA  1 
ATOM   1051 C C   . ASP A 1 231 ? 133.600 152.641 177.850 1.00 60.65 ? 231 ASP A C   1 
ATOM   1052 O O   . ASP A 1 231 ? 133.536 151.613 177.171 1.00 62.93 ? 231 ASP A O   1 
ATOM   1053 C CB  . ASP A 1 231 ? 134.257 154.153 175.949 1.00 54.35 ? 231 ASP A CB  1 
ATOM   1054 N N   . ASP A 1 232 ? 132.915 152.800 178.978 1.00 56.52 ? 232 ASP A N   1 
ATOM   1055 C CA  . ASP A 1 232 ? 132.157 151.712 179.580 1.00 54.68 ? 232 ASP A CA  1 
ATOM   1056 C C   . ASP A 1 232 ? 130.796 151.492 178.935 1.00 59.30 ? 232 ASP A C   1 
ATOM   1057 O O   . ASP A 1 232 ? 130.201 150.430 179.142 1.00 64.84 ? 232 ASP A O   1 
ATOM   1058 C CB  . ASP A 1 232 ? 131.970 151.972 181.078 1.00 52.84 ? 232 ASP A CB  1 
ATOM   1059 N N   . ASN A 1 233 ? 130.291 152.456 178.161 1.00 61.84 ? 233 ASN A N   1 
ATOM   1060 C CA  . ASN A 1 233 ? 129.015 152.319 177.472 1.00 64.26 ? 233 ASN A CA  1 
ATOM   1061 C C   . ASN A 1 233 ? 129.164 151.968 176.001 1.00 59.60 ? 233 ASN A C   1 
ATOM   1062 O O   . ASN A 1 233 ? 128.235 151.398 175.422 1.00 56.10 ? 233 ASN A O   1 
ATOM   1063 C CB  . ASN A 1 233 ? 128.197 153.612 177.596 1.00 65.27 ? 233 ASN A CB  1 
ATOM   1064 C CG  . ASN A 1 233 ? 126.719 153.347 177.804 1.00 63.03 ? 233 ASN A CG  1 
ATOM   1065 O OD1 . ASN A 1 233 ? 126.162 152.406 177.241 1.00 57.51 ? 233 ASN A OD1 1 
ATOM   1066 N ND2 . ASN A 1 233 ? 126.077 154.176 178.618 1.00 61.40 ? 233 ASN A ND2 1 
ATOM   1067 N N   . PHE A 1 234 ? 130.292 152.302 175.381 1.00 56.24 ? 234 PHE A N   1 
ATOM   1068 C CA  . PHE A 1 234 ? 130.575 151.845 174.029 1.00 54.33 ? 234 PHE A CA  1 
ATOM   1069 C C   . PHE A 1 234 ? 131.019 150.391 174.003 1.00 55.39 ? 234 PHE A C   1 
ATOM   1070 O O   . PHE A 1 234 ? 130.729 149.681 173.036 1.00 52.30 ? 234 PHE A O   1 
ATOM   1071 C CB  . PHE A 1 234 ? 131.652 152.727 173.390 1.00 55.16 ? 234 PHE A CB  1 
ATOM   1072 C CG  . PHE A 1 234 ? 132.395 152.063 172.266 1.00 58.85 ? 234 PHE A CG  1 
ATOM   1073 C CD1 . PHE A 1 234 ? 131.768 151.809 171.058 1.00 59.32 ? 234 PHE A CD1 1 
ATOM   1074 C CD2 . PHE A 1 234 ? 133.720 151.698 172.415 1.00 57.02 ? 234 PHE A CD2 1 
ATOM   1075 C CE1 . PHE A 1 234 ? 132.450 151.201 170.022 1.00 56.79 ? 234 PHE A CE1 1 
ATOM   1076 C CE2 . PHE A 1 234 ? 134.404 151.090 171.382 1.00 61.84 ? 234 PHE A CE2 1 
ATOM   1077 C CZ  . PHE A 1 234 ? 133.768 150.842 170.185 1.00 54.88 ? 234 PHE A CZ  1 
ATOM   1078 N N   . VAL A 1 235 ? 131.709 149.931 175.049 1.00 53.03 ? 235 VAL A N   1 
ATOM   1079 C CA  . VAL A 1 235 ? 132.118 148.531 175.114 1.00 47.68 ? 235 VAL A CA  1 
ATOM   1080 C C   . VAL A 1 235 ? 130.894 147.630 175.192 1.00 47.69 ? 235 VAL A C   1 
ATOM   1081 O O   . VAL A 1 235 ? 130.844 146.571 174.557 1.00 52.72 ? 235 VAL A O   1 
ATOM   1082 C CB  . VAL A 1 235 ? 133.067 148.312 176.309 1.00 45.15 ? 235 VAL A CB  1 
ATOM   1083 C CG1 . VAL A 1 235 ? 133.150 146.840 176.697 1.00 46.65 ? 235 VAL A CG1 1 
ATOM   1084 C CG2 . VAL A 1 235 ? 134.447 148.849 175.992 1.00 49.69 ? 235 VAL A CG2 1 
ATOM   1085 N N   . LEU A 1 236 ? 129.896 148.027 175.983 1.00 46.67 ? 236 LEU A N   1 
ATOM   1086 C CA  . LEU A 1 236 ? 128.714 147.189 176.158 1.00 49.46 ? 236 LEU A CA  1 
ATOM   1087 C C   . LEU A 1 236 ? 127.929 147.047 174.860 1.00 45.23 ? 236 LEU A C   1 
ATOM   1088 O O   . LEU A 1 236 ? 127.527 145.937 174.493 1.00 46.89 ? 236 LEU A O   1 
ATOM   1089 C CB  . LEU A 1 236 ? 127.827 147.770 177.257 1.00 52.02 ? 236 LEU A CB  1 
ATOM   1090 C CG  . LEU A 1 236 ? 126.626 146.913 177.654 1.00 51.02 ? 236 LEU A CG  1 
ATOM   1091 C CD1 . LEU A 1 236 ? 126.519 146.823 179.166 1.00 49.87 ? 236 LEU A CD1 1 
ATOM   1092 C CD2 . LEU A 1 236 ? 125.341 147.470 177.056 1.00 49.87 ? 236 LEU A CD2 1 
ATOM   1093 N N   . ILE A 1 237 ? 127.709 148.155 174.148 1.00 48.77 ? 237 ILE A N   1 
ATOM   1094 C CA  . ILE A 1 237 ? 126.913 148.147 172.922 1.00 46.36 ? 237 ILE A CA  1 
ATOM   1095 C C   . ILE A 1 237 ? 127.765 148.023 171.667 1.00 46.42 ? 237 ILE A C   1 
ATOM   1096 O O   . ILE A 1 237 ? 127.248 147.587 170.627 1.00 43.87 ? 237 ILE A O   1 
ATOM   1097 C CB  . ILE A 1 237 ? 126.026 149.410 172.836 1.00 49.68 ? 237 ILE A CB  1 
ATOM   1098 C CG1 . ILE A 1 237 ? 124.820 149.161 171.929 1.00 52.11 ? 237 ILE A CG1 1 
ATOM   1099 C CG2 . ILE A 1 237 ? 126.821 150.617 172.355 1.00 49.01 ? 237 ILE A CG2 1 
ATOM   1100 C CD1 . ILE A 1 237 ? 123.848 150.322 171.879 1.00 53.67 ? 237 ILE A CD1 1 
ATOM   1101 N N   . GLY A 1 238 ? 129.043 148.389 171.724 1.00 55.28 ? 238 GLY A N   1 
ATOM   1102 C CA  . GLY A 1 238 ? 129.918 148.276 170.573 1.00 54.04 ? 238 GLY A CA  1 
ATOM   1103 C C   . GLY A 1 238 ? 130.497 146.888 170.410 1.00 49.69 ? 238 GLY A C   1 
ATOM   1104 O O   . GLY A 1 238 ? 130.897 146.509 169.307 1.00 42.54 ? 238 GLY A O   1 
ATOM   1105 N N   . SER A 1 239 ? 130.567 146.131 171.504 1.00 47.49 ? 239 SER A N   1 
ATOM   1106 C CA  . SER A 1 239 ? 130.907 144.715 171.467 1.00 41.87 ? 239 SER A CA  1 
ATOM   1107 C C   . SER A 1 239 ? 129.677 143.825 171.396 1.00 46.41 ? 239 SER A C   1 
ATOM   1108 O O   . SER A 1 239 ? 129.819 142.608 171.256 1.00 52.13 ? 239 SER A O   1 
ATOM   1109 C CB  . SER A 1 239 ? 131.738 144.333 172.695 1.00 43.28 ? 239 SER A CB  1 
ATOM   1110 O OG  . SER A 1 239 ? 130.913 143.848 173.737 1.00 30.56 ? 239 SER A OG  1 
ATOM   1111 N N   . PHE A 1 240 ? 128.477 144.395 171.499 1.00 44.00 ? 240 PHE A N   1 
ATOM   1112 C CA  . PHE A 1 240 ? 127.248 143.636 171.324 1.00 46.07 ? 240 PHE A CA  1 
ATOM   1113 C C   . PHE A 1 240 ? 126.909 143.439 169.853 1.00 47.63 ? 240 PHE A C   1 
ATOM   1114 O O   . PHE A 1 240 ? 126.598 142.319 169.437 1.00 43.77 ? 240 PHE A O   1 
ATOM   1115 C CB  . PHE A 1 240 ? 126.094 144.345 172.035 1.00 43.03 ? 240 PHE A CB  1 
ATOM   1116 C CG  . PHE A 1 240 ? 124.744 143.787 171.703 1.00 44.38 ? 240 PHE A CG  1 
ATOM   1117 C CD1 . PHE A 1 240 ? 124.359 142.546 172.170 1.00 44.85 ? 240 PHE A CD1 1 
ATOM   1118 C CD2 . PHE A 1 240 ? 123.860 144.508 170.922 1.00 45.96 ? 240 PHE A CD2 1 
ATOM   1119 C CE1 . PHE A 1 240 ? 123.118 142.034 171.864 1.00 50.88 ? 240 PHE A CE1 1 
ATOM   1120 C CE2 . PHE A 1 240 ? 122.618 144.001 170.612 1.00 45.41 ? 240 PHE A CE2 1 
ATOM   1121 C CZ  . PHE A 1 240 ? 122.246 142.763 171.084 1.00 50.46 ? 240 PHE A CZ  1 
ATOM   1122 N N   . VAL A 1 241 ? 126.977 144.507 169.052 1.00 43.10 ? 241 VAL A N   1 
ATOM   1123 C CA  . VAL A 1 241 ? 126.716 144.398 167.618 1.00 37.65 ? 241 VAL A CA  1 
ATOM   1124 C C   . VAL A 1 241 ? 127.917 143.885 166.838 1.00 36.59 ? 241 VAL A C   1 
ATOM   1125 O O   . VAL A 1 241 ? 127.768 143.540 165.657 1.00 37.11 ? 241 VAL A O   1 
ATOM   1126 C CB  . VAL A 1 241 ? 126.271 145.744 167.003 1.00 37.62 ? 241 VAL A CB  1 
ATOM   1127 C CG1 . VAL A 1 241 ? 124.930 146.174 167.574 1.00 39.60 ? 241 VAL A CG1 1 
ATOM   1128 C CG2 . VAL A 1 241 ? 127.319 146.850 167.198 1.00 42.01 ? 241 VAL A CG2 1 
ATOM   1129 N N   . SER A 1 242 ? 129.101 143.823 167.453 1.00 42.16 ? 242 SER A N   1 
ATOM   1130 C CA  . SER A 1 242 ? 130.306 143.363 166.776 1.00 42.52 ? 242 SER A CA  1 
ATOM   1131 C C   . SER A 1 242 ? 130.585 141.881 166.973 1.00 39.46 ? 242 SER A C   1 
ATOM   1132 O O   . SER A 1 242 ? 131.225 141.278 166.106 1.00 39.37 ? 242 SER A O   1 
ATOM   1133 C CB  . SER A 1 242 ? 131.527 144.149 167.265 1.00 42.58 ? 242 SER A CB  1 
ATOM   1134 O OG  . SER A 1 242 ? 132.697 143.358 167.189 1.00 43.34 ? 242 SER A OG  1 
ATOM   1135 N N   . PHE A 1 243 ? 130.156 141.294 168.092 1.00 28.71 ? 243 PHE A N   1 
ATOM   1136 C CA  . PHE A 1 243 ? 130.332 139.869 168.348 1.00 24.96 ? 243 PHE A CA  1 
ATOM   1137 C C   . PHE A 1 243 ? 129.021 139.135 168.571 1.00 33.20 ? 243 PHE A C   1 
ATOM   1138 O O   . PHE A 1 243 ? 128.784 138.105 167.931 1.00 52.03 ? 243 PHE A O   1 
ATOM   1139 C CB  . PHE A 1 243 ? 131.241 139.649 169.559 1.00 30.04 ? 243 PHE A CB  1 
ATOM   1140 C CG  . PHE A 1 243 ? 131.535 138.204 169.828 1.00 31.75 ? 243 PHE A CG  1 
ATOM   1141 C CD1 . PHE A 1 243 ? 132.345 137.481 168.973 1.00 28.35 ? 243 PHE A CD1 1 
ATOM   1142 C CD2 . PHE A 1 243 ? 130.999 137.566 170.930 1.00 37.40 ? 243 PHE A CD2 1 
ATOM   1143 C CE1 . PHE A 1 243 ? 132.617 136.155 169.212 1.00 31.61 ? 243 PHE A CE1 1 
ATOM   1144 C CE2 . PHE A 1 243 ? 131.268 136.237 171.174 1.00 33.97 ? 243 PHE A CE2 1 
ATOM   1145 C CZ  . PHE A 1 243 ? 132.079 135.532 170.315 1.00 36.17 ? 243 PHE A CZ  1 
ATOM   1146 N N   . PHE A 1 244 ? 128.153 139.629 169.455 1.00 26.84 ? 244 PHE A N   1 
ATOM   1147 C CA  . PHE A 1 244 ? 127.010 138.822 169.870 1.00 40.14 ? 244 PHE A CA  1 
ATOM   1148 C C   . PHE A 1 244 ? 125.915 138.769 168.813 1.00 40.20 ? 244 PHE A C   1 
ATOM   1149 O O   . PHE A 1 244 ? 125.168 137.787 168.762 1.00 38.34 ? 244 PHE A O   1 
ATOM   1150 C CB  . PHE A 1 244 ? 126.442 139.345 171.191 1.00 33.41 ? 244 PHE A CB  1 
ATOM   1151 C CG  . PHE A 1 244 ? 127.343 139.114 172.382 1.00 34.81 ? 244 PHE A CG  1 
ATOM   1152 C CD1 . PHE A 1 244 ? 127.840 137.855 172.674 1.00 35.00 ? 244 PHE A CD1 1 
ATOM   1153 C CD2 . PHE A 1 244 ? 127.681 140.164 173.215 1.00 44.88 ? 244 PHE A CD2 1 
ATOM   1154 C CE1 . PHE A 1 244 ? 128.661 137.655 173.760 1.00 40.74 ? 244 PHE A CE1 1 
ATOM   1155 C CE2 . PHE A 1 244 ? 128.498 139.965 174.304 1.00 41.57 ? 244 PHE A CE2 1 
ATOM   1156 C CZ  . PHE A 1 244 ? 128.987 138.711 174.576 1.00 39.68 ? 244 PHE A CZ  1 
ATOM   1157 N N   . ILE A 1 245 ? 125.790 139.793 167.976 1.00 35.88 ? 245 ILE A N   1 
ATOM   1158 C CA  . ILE A 1 245 ? 124.839 139.746 166.867 1.00 33.27 ? 245 ILE A CA  1 
ATOM   1159 C C   . ILE A 1 245 ? 125.421 138.870 165.760 1.00 33.74 ? 245 ILE A C   1 
ATOM   1160 O O   . ILE A 1 245 ? 124.678 138.084 165.159 1.00 37.09 ? 245 ILE A O   1 
ATOM   1161 C CB  . ILE A 1 245 ? 124.491 141.156 166.359 1.00 40.03 ? 245 ILE A CB  1 
ATOM   1162 C CG1 . ILE A 1 245 ? 123.679 141.936 167.407 1.00 42.97 ? 245 ILE A CG1 1 
ATOM   1163 C CG2 . ILE A 1 245 ? 123.734 141.078 165.035 1.00 31.89 ? 245 ILE A CG2 1 
ATOM   1164 C CD1 . ILE A 1 245 ? 122.312 141.355 167.780 1.00 42.07 ? 245 ILE A CD1 1 
ATOM   1165 N N   . PRO A 1 246 ? 126.712 138.972 165.424 1.00 34.56 ? 246 PRO A N   1 
ATOM   1166 C CA  . PRO A 1 246 ? 127.314 137.942 164.562 1.00 32.69 ? 246 PRO A CA  1 
ATOM   1167 C C   . PRO A 1 246 ? 127.364 136.556 165.187 1.00 26.80 ? 246 PRO A C   1 
ATOM   1168 O O   . PRO A 1 246 ? 127.562 135.586 164.447 1.00 33.61 ? 246 PRO A O   1 
ATOM   1169 C CB  . PRO A 1 246 ? 128.729 138.470 164.294 1.00 23.15 ? 246 PRO A CB  1 
ATOM   1170 C CG  . PRO A 1 246 ? 128.842 139.749 164.983 1.00 32.79 ? 246 PRO A CG  1 
ATOM   1171 C CD  . PRO A 1 246 ? 127.506 140.208 165.406 1.00 35.97 ? 246 PRO A CD  1 
ATOM   1172 N N   . LEU A 1 247 ? 127.218 136.423 166.505 1.00 12.40 ? 247 LEU A N   1 
ATOM   1173 C CA  . LEU A 1 247 ? 127.170 135.109 167.136 1.00 19.75 ? 247 LEU A CA  1 
ATOM   1174 C C   . LEU A 1 247 ? 125.774 134.502 167.128 1.00 31.87 ? 247 LEU A C   1 
ATOM   1175 O O   . LEU A 1 247 ? 125.633 133.310 166.845 1.00 45.87 ? 247 LEU A O   1 
ATOM   1176 C CB  . LEU A 1 247 ? 127.688 135.176 168.575 1.00 30.60 ? 247 LEU A CB  1 
ATOM   1177 C CG  . LEU A 1 247 ? 127.961 133.820 169.240 1.00 29.51 ? 247 LEU A CG  1 
ATOM   1178 C CD1 . LEU A 1 247 ? 129.337 133.305 168.876 1.00 29.78 ? 247 LEU A CD1 1 
ATOM   1179 C CD2 . LEU A 1 247 ? 127.819 133.931 170.745 1.00 24.32 ? 247 LEU A CD2 1 
ATOM   1180 N N   . THR A 1 248 ? 124.729 135.270 167.440 1.00 23.03 ? 248 THR A N   1 
ATOM   1181 C CA  . THR A 1 248 ? 123.390 134.711 167.308 1.00 23.18 ? 248 THR A CA  1 
ATOM   1182 C C   . THR A 1 248 ? 123.035 134.450 165.853 1.00 26.63 ? 248 THR A C   1 
ATOM   1183 O O   . THR A 1 248 ? 122.225 133.562 165.578 1.00 35.60 ? 248 THR A O   1 
ATOM   1184 C CB  . THR A 1 248 ? 122.334 135.620 167.949 1.00 30.86 ? 248 THR A CB  1 
ATOM   1185 O OG1 . THR A 1 248 ? 121.039 135.027 167.793 1.00 33.62 ? 248 THR A OG1 1 
ATOM   1186 C CG2 . THR A 1 248 ? 122.309 137.002 167.320 1.00 33.47 ? 248 THR A CG2 1 
ATOM   1187 N N   . ILE A 1 249 ? 123.625 135.195 164.918 1.00 27.82 ? 249 ILE A N   1 
ATOM   1188 C CA  . ILE A 1 249 ? 123.431 134.905 163.500 1.00 25.89 ? 249 ILE A CA  1 
ATOM   1189 C C   . ILE A 1 249 ? 124.134 133.606 163.128 1.00 22.47 ? 249 ILE A C   1 
ATOM   1190 O O   . ILE A 1 249 ? 123.640 132.829 162.304 1.00 26.37 ? 249 ILE A O   1 
ATOM   1191 C CB  . ILE A 1 249 ? 123.920 136.086 162.642 1.00 25.30 ? 249 ILE A CB  1 
ATOM   1192 C CG1 . ILE A 1 249 ? 122.938 137.254 162.760 1.00 26.37 ? 249 ILE A CG1 1 
ATOM   1193 C CG2 . ILE A 1 249 ? 124.083 135.664 161.178 1.00 29.92 ? 249 ILE A CG2 1 
ATOM   1194 C CD1 . ILE A 1 249 ? 123.465 138.574 162.238 1.00 26.91 ? 249 ILE A CD1 1 
ATOM   1195 N N   . MET A 1 250 ? 125.308 133.362 163.709 1.00 30.77 ? 250 MET A N   1 
ATOM   1196 C CA  . MET A 1 250 ? 126.045 132.144 163.394 1.00 24.80 ? 250 MET A CA  1 
ATOM   1197 C C   . MET A 1 250 ? 125.428 130.919 164.050 1.00 25.77 ? 250 MET A C   1 
ATOM   1198 O O   . MET A 1 250 ? 125.518 129.818 163.499 1.00 45.78 ? 250 MET A O   1 
ATOM   1199 C CB  . MET A 1 250 ? 127.500 132.278 163.828 1.00 33.62 ? 250 MET A CB  1 
ATOM   1200 C CG  . MET A 1 250 ? 128.386 132.933 162.802 1.00 31.28 ? 250 MET A CG  1 
ATOM   1201 S SD  . MET A 1 250 ? 130.092 132.940 163.347 1.00 58.37 ? 250 MET A SD  1 
ATOM   1202 C CE  . MET A 1 250 ? 130.851 133.841 162.016 1.00 31.44 ? 250 MET A CE  1 
ATOM   1203 N N   . VAL A 1 251 ? 124.825 131.076 165.228 1.00 17.79 ? 251 VAL A N   1 
ATOM   1204 C CA  . VAL A 1 251 ? 124.196 129.935 165.884 1.00 27.97 ? 251 VAL A CA  1 
ATOM   1205 C C   . VAL A 1 251 ? 123.006 129.445 165.071 1.00 28.00 ? 251 VAL A C   1 
ATOM   1206 O O   . VAL A 1 251 ? 122.835 128.238 164.864 1.00 21.82 ? 251 VAL A O   1 
ATOM   1207 C CB  . VAL A 1 251 ? 123.796 130.310 167.322 1.00 29.63 ? 251 VAL A CB  1 
ATOM   1208 C CG1 . VAL A 1 251 ? 122.745 129.353 167.882 1.00 31.65 ? 251 VAL A CG1 1 
ATOM   1209 C CG2 . VAL A 1 251 ? 125.021 130.326 168.210 1.00 26.81 ? 251 VAL A CG2 1 
ATOM   1210 N N   . ILE A 1 252 ? 122.161 130.364 164.603 1.00 21.11 ? 252 ILE A N   1 
ATOM   1211 C CA  . ILE A 1 252 ? 121.008 129.965 163.802 1.00 25.78 ? 252 ILE A CA  1 
ATOM   1212 C C   . ILE A 1 252 ? 121.461 129.466 162.437 1.00 32.01 ? 252 ILE A C   1 
ATOM   1213 O O   . ILE A 1 252 ? 120.904 128.505 161.896 1.00 33.70 ? 252 ILE A O   1 
ATOM   1214 C CB  . ILE A 1 252 ? 120.000 131.123 163.669 1.00 23.48 ? 252 ILE A CB  1 
ATOM   1215 C CG1 . ILE A 1 252 ? 119.506 131.615 165.038 1.00 22.63 ? 252 ILE A CG1 1 
ATOM   1216 C CG2 . ILE A 1 252 ? 118.812 130.697 162.823 1.00 33.46 ? 252 ILE A CG2 1 
ATOM   1217 C CD1 . ILE A 1 252 ? 119.302 133.117 165.124 1.00 29.14 ? 252 ILE A CD1 1 
ATOM   1218 N N   . THR A 1 253 ? 122.463 130.120 161.850 1.00 34.74 ? 253 THR A N   1 
ATOM   1219 C CA  . THR A 1 253 ? 122.970 129.685 160.555 1.00 23.83 ? 253 THR A CA  1 
ATOM   1220 C C   . THR A 1 253 ? 123.597 128.302 160.645 1.00 25.42 ? 253 THR A C   1 
ATOM   1221 O O   . THR A 1 253 ? 123.410 127.472 159.751 1.00 35.33 ? 253 THR A O   1 
ATOM   1222 C CB  . THR A 1 253 ? 123.984 130.695 160.024 1.00 25.59 ? 253 THR A CB  1 
ATOM   1223 O OG1 . THR A 1 253 ? 123.365 131.981 159.913 1.00 35.63 ? 253 THR A OG1 1 
ATOM   1224 C CG2 . THR A 1 253 ? 124.487 130.277 158.669 1.00 27.73 ? 253 THR A CG2 1 
ATOM   1225 N N   . TYR A 1 254 ? 124.353 128.038 161.709 1.00 27.18 ? 254 TYR A N   1 
ATOM   1226 C CA  . TYR A 1 254 ? 124.952 126.719 161.868 1.00 18.03 ? 254 TYR A CA  1 
ATOM   1227 C C   . TYR A 1 254 ? 123.905 125.662 162.183 1.00 26.24 ? 254 TYR A C   1 
ATOM   1228 O O   . TYR A 1 254 ? 123.961 124.559 161.633 1.00 44.96 ? 254 TYR A O   1 
ATOM   1229 C CB  . TYR A 1 254 ? 126.012 126.753 162.963 1.00 24.52 ? 254 TYR A CB  1 
ATOM   1230 C CG  . TYR A 1 254 ? 126.555 125.396 163.327 1.00 21.04 ? 254 TYR A CG  1 
ATOM   1231 C CD1 . TYR A 1 254 ? 127.366 124.697 162.454 1.00 25.68 ? 254 TYR A CD1 1 
ATOM   1232 C CD2 . TYR A 1 254 ? 126.266 124.820 164.552 1.00 31.95 ? 254 TYR A CD2 1 
ATOM   1233 C CE1 . TYR A 1 254 ? 127.866 123.460 162.786 1.00 29.94 ? 254 TYR A CE1 1 
ATOM   1234 C CE2 . TYR A 1 254 ? 126.762 123.583 164.892 1.00 31.89 ? 254 TYR A CE2 1 
ATOM   1235 C CZ  . TYR A 1 254 ? 127.562 122.909 164.007 1.00 29.60 ? 254 TYR A CZ  1 
ATOM   1236 O OH  . TYR A 1 254 ? 128.061 121.676 164.344 1.00 30.64 ? 254 TYR A OH  1 
ATOM   1237 N N   . PHE A 1 255 ? 122.947 125.972 163.058 1.00 18.57 ? 255 PHE A N   1 
ATOM   1238 C CA  . PHE A 1 255 ? 121.895 125.009 163.365 1.00 27.49 ? 255 PHE A CA  1 
ATOM   1239 C C   . PHE A 1 255 ? 121.050 124.708 162.135 1.00 27.51 ? 255 PHE A C   1 
ATOM   1240 O O   . PHE A 1 255 ? 120.674 123.555 161.901 1.00 34.42 ? 255 PHE A O   1 
ATOM   1241 C CB  . PHE A 1 255 ? 121.018 125.535 164.499 1.00 35.39 ? 255 PHE A CB  1 
ATOM   1242 C CG  . PHE A 1 255 ? 119.627 124.963 164.511 1.00 37.78 ? 255 PHE A CG  1 
ATOM   1243 C CD1 . PHE A 1 255 ? 119.402 123.650 164.887 1.00 36.79 ? 255 PHE A CD1 1 
ATOM   1244 C CD2 . PHE A 1 255 ? 118.542 125.745 164.157 1.00 33.36 ? 255 PHE A CD2 1 
ATOM   1245 C CE1 . PHE A 1 255 ? 118.125 123.129 164.902 1.00 35.34 ? 255 PHE A CE1 1 
ATOM   1246 C CE2 . PHE A 1 255 ? 117.265 125.229 164.170 1.00 35.16 ? 255 PHE A CE2 1 
ATOM   1247 C CZ  . PHE A 1 255 ? 117.056 123.920 164.544 1.00 36.81 ? 255 PHE A CZ  1 
ATOM   1248 N N   . LEU A 1 256 ? 120.743 125.729 161.339 1.00 27.10 ? 256 LEU A N   1 
ATOM   1249 C CA  . LEU A 1 256 ? 119.944 125.524 160.138 1.00 31.23 ? 256 LEU A CA  1 
ATOM   1250 C C   . LEU A 1 256 ? 120.719 124.795 159.048 1.00 28.86 ? 256 LEU A C   1 
ATOM   1251 O O   . LEU A 1 256 ? 120.138 123.972 158.335 1.00 39.66 ? 256 LEU A O   1 
ATOM   1252 C CB  . LEU A 1 256 ? 119.446 126.869 159.611 1.00 36.85 ? 256 LEU A CB  1 
ATOM   1253 C CG  . LEU A 1 256 ? 118.288 127.525 160.364 1.00 34.22 ? 256 LEU A CG  1 
ATOM   1254 C CD1 . LEU A 1 256 ? 118.059 128.926 159.842 1.00 35.67 ? 256 LEU A CD1 1 
ATOM   1255 C CD2 . LEU A 1 256 ? 117.012 126.712 160.238 1.00 33.24 ? 256 LEU A CD2 1 
ATOM   1256 N N   . THR A 1 257 ? 122.014 125.082 158.892 1.00 24.49 ? 257 THR A N   1 
ATOM   1257 C CA  . THR A 1 257 ? 122.795 124.415 157.854 1.00 22.38 ? 257 THR A CA  1 
ATOM   1258 C C   . THR A 1 257 ? 122.936 122.928 158.141 1.00 23.35 ? 257 THR A C   1 
ATOM   1259 O O   . THR A 1 257 ? 122.765 122.100 157.240 1.00 31.81 ? 257 THR A O   1 
ATOM   1260 C CB  . THR A 1 257 ? 124.175 125.057 157.725 1.00 30.34 ? 257 THR A CB  1 
ATOM   1261 O OG1 . THR A 1 257 ? 124.039 126.463 157.496 1.00 37.87 ? 257 THR A OG1 1 
ATOM   1262 C CG2 . THR A 1 257 ? 124.944 124.444 156.574 1.00 29.91 ? 257 THR A CG2 1 
ATOM   1263 N N   . ILE A 1 258 ? 123.252 122.568 159.385 1.00 17.98 ? 258 ILE A N   1 
ATOM   1264 C CA  . ILE A 1 258 ? 123.358 121.158 159.740 1.00 24.60 ? 258 ILE A CA  1 
ATOM   1265 C C   . ILE A 1 258 ? 121.996 120.486 159.650 1.00 38.16 ? 258 ILE A C   1 
ATOM   1266 O O   . ILE A 1 258 ? 121.891 119.312 159.278 1.00 45.60 ? 258 ILE A O   1 
ATOM   1267 C CB  . ILE A 1 258 ? 123.974 121.000 161.142 1.00 20.62 ? 258 ILE A CB  1 
ATOM   1268 C CG1 . ILE A 1 258 ? 125.387 121.598 161.203 1.00 25.03 ? 258 ILE A CG1 1 
ATOM   1269 C CG2 . ILE A 1 258 ? 123.986 119.540 161.555 1.00 32.81 ? 258 ILE A CG2 1 
ATOM   1270 C CD1 . ILE A 1 258 ? 126.398 121.000 160.237 1.00 25.56 ? 258 ILE A CD1 1 
ATOM   1271 N N   . LYS A 1 259 ? 120.932 121.211 159.994 1.00 35.32 ? 259 LYS A N   1 
ATOM   1272 C CA  . LYS A 1 259 ? 119.592 120.657 159.854 1.00 34.40 ? 259 LYS A CA  1 
ATOM   1273 C C   . LYS A 1 259 ? 119.280 120.354 158.394 1.00 33.95 ? 259 LYS A C   1 
ATOM   1274 O O   . LYS A 1 259 ? 118.621 119.354 158.091 1.00 40.54 ? 259 LYS A O   1 
ATOM   1275 C CB  . LYS A 1 259 ? 118.570 121.627 160.455 1.00 38.78 ? 259 LYS A CB  1 
ATOM   1276 C CG  . LYS A 1 259 ? 117.102 121.349 160.132 1.00 40.58 ? 259 LYS A CG  1 
ATOM   1277 C CD  . LYS A 1 259 ? 116.198 122.360 160.815 1.00 41.79 ? 259 LYS A CD  1 
ATOM   1278 C CE  . LYS A 1 259 ? 114.774 122.267 160.297 1.00 47.20 ? 259 LYS A CE  1 
ATOM   1279 N NZ  . LYS A 1 259 ? 113.867 123.238 160.968 1.00 44.48 ? 259 LYS A NZ  1 
ATOM   1280 N N   . SER A 1 260 ? 119.740 121.208 157.476 1.00 35.07 ? 260 SER A N   1 
ATOM   1281 C CA  . SER A 1 260 ? 119.449 121.036 156.057 1.00 34.45 ? 260 SER A CA  1 
ATOM   1282 C C   . SER A 1 260 ? 120.453 120.145 155.333 1.00 35.97 ? 260 SER A C   1 
ATOM   1283 O O   . SER A 1 260 ? 120.201 119.776 154.182 1.00 39.75 ? 260 SER A O   1 
ATOM   1284 C CB  . SER A 1 260 ? 119.395 122.397 155.365 1.00 38.30 ? 260 SER A CB  1 
ATOM   1285 O OG  . SER A 1 260 ? 119.514 122.249 153.963 1.00 47.46 ? 260 SER A OG  1 
ATOM   1286 N N   . LEU A 1 261 ? 121.579 119.806 155.959 1.00 28.20 ? 261 LEU A N   1 
ATOM   1287 C CA  . LEU A 1 261 ? 122.524 118.849 155.395 1.00 22.75 ? 261 LEU A CA  1 
ATOM   1288 C C   . LEU A 1 261 ? 122.218 117.411 155.797 1.00 29.21 ? 261 LEU A C   1 
ATOM   1289 O O   . LEU A 1 261 ? 122.925 116.501 155.355 1.00 41.23 ? 261 LEU A O   1 
ATOM   1290 C CB  . LEU A 1 261 ? 123.962 119.198 155.817 1.00 29.30 ? 261 LEU A CB  1 
ATOM   1291 C CG  . LEU A 1 261 ? 124.866 120.055 154.916 1.00 25.77 ? 261 LEU A CG  1 
ATOM   1292 C CD1 . LEU A 1 261 ? 126.273 120.071 155.478 1.00 31.14 ? 261 LEU A CD1 1 
ATOM   1293 C CD2 . LEU A 1 261 ? 124.910 119.592 153.470 1.00 23.62 ? 261 LEU A CD2 1 
ATOM   1294 N N   . GLN A 1 262 ? 121.193 117.185 156.616 1.00 33.95 ? 262 GLN A N   1 
ATOM   1295 C CA  . GLN A 1 262 ? 120.795 115.844 157.035 1.00 42.60 ? 262 GLN A CA  1 
ATOM   1296 C C   . GLN A 1 262 ? 119.316 115.614 156.736 1.00 39.30 ? 262 GLN A C   1 
ATOM   1297 O O   . GLN A 1 262 ? 118.831 115.943 155.653 1.00 35.43 ? 262 GLN A O   1 
ATOM   1298 C CB  . GLN A 1 262 ? 121.095 115.649 158.527 1.00 36.98 ? 262 GLN A CB  1 
ATOM   1299 C CG  . GLN A 1 262 ? 120.025 116.169 159.485 1.00 37.08 ? 262 GLN A CG  1 
ATOM   1300 C CD  . GLN A 1 262 ? 120.479 116.160 160.931 1.00 44.00 ? 262 GLN A CD  1 
ATOM   1301 O OE1 . GLN A 1 262 ? 121.674 116.134 161.221 1.00 44.53 ? 262 GLN A OE1 1 
ATOM   1302 N NE2 . GLN A 1 262 ? 119.521 116.190 161.849 1.00 46.68 ? 262 GLN A NE2 1 
ATOM   1303 N N   . ILE A 1 315 ? 126.425 109.307 150.779 1.00 52.92 ? 315 ILE A N   1 
ATOM   1304 C CA  . ILE A 1 315 ? 126.223 110.682 151.215 1.00 51.93 ? 315 ILE A CA  1 
ATOM   1305 C C   . ILE A 1 315 ? 127.339 111.101 152.160 1.00 49.28 ? 315 ILE A C   1 
ATOM   1306 O O   . ILE A 1 315 ? 127.106 111.832 153.118 1.00 47.05 ? 315 ILE A O   1 
ATOM   1307 C CB  . ILE A 1 315 ? 124.853 110.855 151.891 1.00 43.89 ? 315 ILE A CB  1 
ATOM   1308 N N   . SER A 1 316 ? 128.556 110.625 151.874 1.00 50.35 ? 316 SER A N   1 
ATOM   1309 C CA  . SER A 1 316 ? 129.722 110.942 152.739 1.00 45.59 ? 316 SER A CA  1 
ATOM   1310 C C   . SER A 1 316 ? 130.133 112.411 152.558 1.00 43.88 ? 316 SER A C   1 
ATOM   1311 O O   . SER A 1 316 ? 130.556 113.030 153.555 1.00 48.37 ? 316 SER A O   1 
ATOM   1312 C CB  . SER A 1 316 ? 130.876 110.016 152.452 1.00 47.93 ? 316 SER A CB  1 
ATOM   1313 O OG  . SER A 1 316 ? 130.503 108.662 152.665 1.00 48.13 ? 316 SER A OG  1 
ATOM   1314 N N   . ASN A 1 317 ? 130.030 112.938 151.334 1.00 41.72 ? 317 ASN A N   1 
ATOM   1315 C CA  . ASN A 1 317 ? 130.441 114.320 151.107 1.00 46.58 ? 317 ASN A CA  1 
ATOM   1316 C C   . ASN A 1 317 ? 129.625 115.286 151.951 1.00 41.72 ? 317 ASN A C   1 
ATOM   1317 O O   . ASN A 1 317 ? 130.155 116.299 152.419 1.00 33.17 ? 317 ASN A O   1 
ATOM   1318 C CB  . ASN A 1 317 ? 130.300 114.680 149.627 1.00 51.65 ? 317 ASN A CB  1 
ATOM   1319 C CG  . ASN A 1 317 ? 131.530 114.332 148.808 1.00 52.58 ? 317 ASN A CG  1 
ATOM   1320 O OD1 . ASN A 1 317 ? 132.590 114.011 149.344 1.00 55.85 ? 317 ASN A OD1 1 
ATOM   1321 N ND2 . ASN A 1 317 ? 131.391 114.401 147.491 1.00 48.57 ? 317 ASN A ND2 1 
ATOM   1322 N N   . GLU A 1 318 ? 128.337 115.003 152.142 1.00 38.66 ? 318 GLU A N   1 
ATOM   1323 C CA  . GLU A 1 318 ? 127.538 115.803 153.059 1.00 32.69 ? 318 GLU A CA  1 
ATOM   1324 C C   . GLU A 1 318 ? 128.025 115.645 154.492 1.00 39.56 ? 318 GLU A C   1 
ATOM   1325 O O   . GLU A 1 318 ? 127.956 116.596 155.276 1.00 39.70 ? 318 GLU A O   1 
ATOM   1326 C CB  . GLU A 1 318 ? 126.069 115.405 152.951 1.00 34.62 ? 318 GLU A CB  1 
ATOM   1327 C CG  . GLU A 1 318 ? 125.514 115.461 151.538 1.00 41.05 ? 318 GLU A CG  1 
ATOM   1328 C CD  . GLU A 1 318 ? 124.186 116.184 151.457 1.00 44.75 ? 318 GLU A CD  1 
ATOM   1329 O OE1 . GLU A 1 318 ? 124.189 117.428 151.363 1.00 48.76 ? 318 GLU A OE1 1 
ATOM   1330 O OE2 . GLU A 1 318 ? 123.138 115.507 151.485 1.00 35.92 ? 318 GLU A OE2 1 
ATOM   1331 N N   . GLN A 1 319 ? 128.511 114.455 154.853 1.00 37.55 ? 319 GLN A N   1 
ATOM   1332 C CA  . GLN A 1 319 ? 129.055 114.241 156.188 1.00 31.24 ? 319 GLN A CA  1 
ATOM   1333 C C   . GLN A 1 319 ? 130.442 114.851 156.346 1.00 37.06 ? 319 GLN A C   1 
ATOM   1334 O O   . GLN A 1 319 ? 130.783 115.319 157.436 1.00 41.10 ? 319 GLN A O   1 
ATOM   1335 C CB  . GLN A 1 319 ? 129.105 112.746 156.503 1.00 24.65 ? 319 GLN A CB  1 
ATOM   1336 N N   . LYS A 1 320 ? 131.257 114.843 155.291 1.00 37.19 ? 320 LYS A N   1 
ATOM   1337 C CA  . LYS A 1 320 ? 132.545 115.527 155.359 1.00 33.66 ? 320 LYS A CA  1 
ATOM   1338 C C   . LYS A 1 320 ? 132.351 117.029 155.521 1.00 32.28 ? 320 LYS A C   1 
ATOM   1339 O O   . LYS A 1 320 ? 133.089 117.677 156.269 1.00 34.44 ? 320 LYS A O   1 
ATOM   1340 C CB  . LYS A 1 320 ? 133.371 115.211 154.109 1.00 40.76 ? 320 LYS A CB  1 
ATOM   1341 C CG  . LYS A 1 320 ? 134.776 115.835 154.060 1.00 38.20 ? 320 LYS A CG  1 
ATOM   1342 C CD  . LYS A 1 320 ? 135.751 115.143 155.015 1.00 41.09 ? 320 LYS A CD  1 
ATOM   1343 C CE  . LYS A 1 320 ? 137.178 115.095 154.470 1.00 41.18 ? 320 LYS A CE  1 
ATOM   1344 N NZ  . LYS A 1 320 ? 138.007 114.071 155.169 1.00 39.74 ? 320 LYS A NZ  1 
ATOM   1345 N N   . ALA A 1 321 ? 131.373 117.603 154.818 1.00 31.60 ? 321 ALA A N   1 
ATOM   1346 C CA  . ALA A 1 321 ? 131.088 119.024 154.980 1.00 29.61 ? 321 ALA A CA  1 
ATOM   1347 C C   . ALA A 1 321 ? 130.575 119.338 156.377 1.00 31.66 ? 321 ALA A C   1 
ATOM   1348 O O   . ALA A 1 321 ? 130.937 120.372 156.945 1.00 36.47 ? 321 ALA A O   1 
ATOM   1349 C CB  . ALA A 1 321 ? 130.073 119.483 153.936 1.00 32.86 ? 321 ALA A CB  1 
ATOM   1350 N N   . CYS A 1 322 ? 129.736 118.467 156.944 1.00 33.19 ? 322 CYS A N   1 
ATOM   1351 C CA  . CYS A 1 322 ? 129.225 118.695 158.293 1.00 35.32 ? 322 CYS A CA  1 
ATOM   1352 C C   . CYS A 1 322 ? 130.348 118.738 159.321 1.00 36.42 ? 322 CYS A C   1 
ATOM   1353 O O   . CYS A 1 322 ? 130.228 119.431 160.336 1.00 43.60 ? 322 CYS A O   1 
ATOM   1354 C CB  . CYS A 1 322 ? 128.219 117.608 158.667 1.00 29.36 ? 322 CYS A CB  1 
ATOM   1355 S SG  . CYS A 1 322 ? 126.520 117.964 158.179 1.00 45.91 ? 322 CYS A SG  1 
ATOM   1356 N N   . LYS A 1 323 ? 131.431 117.999 159.088 1.00 34.03 ? 323 LYS A N   1 
ATOM   1357 C CA  . LYS A 1 323 ? 132.570 118.040 159.995 1.00 38.00 ? 323 LYS A CA  1 
ATOM   1358 C C   . LYS A 1 323 ? 133.395 119.307 159.814 1.00 31.92 ? 323 LYS A C   1 
ATOM   1359 O O   . LYS A 1 323 ? 134.011 119.779 160.774 1.00 33.37 ? 323 LYS A O   1 
ATOM   1360 C CB  . LYS A 1 323 ? 133.444 116.803 159.787 1.00 39.14 ? 323 LYS A CB  1 
ATOM   1361 C CG  . LYS A 1 323 ? 132.906 115.572 160.495 1.00 37.78 ? 323 LYS A CG  1 
ATOM   1362 C CD  . LYS A 1 323 ? 133.715 114.327 160.188 1.00 35.43 ? 323 LYS A CD  1 
ATOM   1363 C CE  . LYS A 1 323 ? 133.125 113.114 160.892 1.00 37.69 ? 323 LYS A CE  1 
ATOM   1364 N NZ  . LYS A 1 323 ? 133.906 111.872 160.643 1.00 39.28 ? 323 LYS A NZ  1 
ATOM   1365 N N   . VAL A 1 324 ? 133.429 119.864 158.602 1.00 27.42 ? 324 VAL A N   1 
ATOM   1366 C CA  . VAL A 1 324 ? 134.163 121.106 158.383 1.00 26.16 ? 324 VAL A CA  1 
ATOM   1367 C C   . VAL A 1 324 ? 133.444 122.272 159.045 1.00 31.11 ? 324 VAL A C   1 
ATOM   1368 O O   . VAL A 1 324 ? 134.079 123.165 159.614 1.00 45.20 ? 324 VAL A O   1 
ATOM   1369 C CB  . VAL A 1 324 ? 134.369 121.353 156.879 1.00 29.35 ? 324 VAL A CB  1 
ATOM   1370 C CG1 . VAL A 1 324 ? 134.915 122.755 156.638 1.00 30.65 ? 324 VAL A CG1 1 
ATOM   1371 C CG2 . VAL A 1 324 ? 135.301 120.311 156.293 1.00 32.51 ? 324 VAL A CG2 1 
ATOM   1372 N N   . LEU A 1 325 ? 132.113 122.299 158.963 1.00 25.78 ? 325 LEU A N   1 
ATOM   1373 C CA  . LEU A 1 325 ? 131.362 123.353 159.632 1.00 28.56 ? 325 LEU A CA  1 
ATOM   1374 C C   . LEU A 1 325 ? 131.549 123.293 161.140 1.00 33.90 ? 325 LEU A C   1 
ATOM   1375 O O   . LEU A 1 325 ? 131.666 124.337 161.788 1.00 31.90 ? 325 LEU A O   1 
ATOM   1376 C CB  . LEU A 1 325 ? 129.876 123.249 159.289 1.00 30.96 ? 325 LEU A CB  1 
ATOM   1377 C CG  . LEU A 1 325 ? 129.461 123.321 157.817 1.00 35.91 ? 325 LEU A CG  1 
ATOM   1378 C CD1 . LEU A 1 325 ? 127.955 123.406 157.711 1.00 29.33 ? 325 LEU A CD1 1 
ATOM   1379 C CD2 . LEU A 1 325 ? 130.097 124.493 157.105 1.00 36.13 ? 325 LEU A CD2 1 
ATOM   1380 N N   . GLY A 1 326 ? 131.575 122.090 161.713 1.00 35.56 ? 326 GLY A N   1 
ATOM   1381 C CA  . GLY A 1 326 ? 131.757 121.973 163.149 1.00 31.74 ? 326 GLY A CA  1 
ATOM   1382 C C   . GLY A 1 326 ? 133.098 122.506 163.614 1.00 35.78 ? 326 GLY A C   1 
ATOM   1383 O O   . GLY A 1 326 ? 133.177 123.206 164.626 1.00 44.44 ? 326 GLY A O   1 
ATOM   1384 N N   . ILE A 1 327 ? 134.168 122.186 162.886 1.00 31.05 ? 327 ILE A N   1 
ATOM   1385 C CA  . ILE A 1 327 ? 135.488 122.683 163.258 1.00 28.71 ? 327 ILE A CA  1 
ATOM   1386 C C   . ILE A 1 327 ? 135.546 124.196 163.108 1.00 29.41 ? 327 ILE A C   1 
ATOM   1387 O O   . ILE A 1 327 ? 136.104 124.896 163.959 1.00 41.83 ? 327 ILE A O   1 
ATOM   1388 C CB  . ILE A 1 327 ? 136.577 121.990 162.418 1.00 31.97 ? 327 ILE A CB  1 
ATOM   1389 C CG1 . ILE A 1 327 ? 136.696 120.515 162.817 1.00 40.11 ? 327 ILE A CG1 1 
ATOM   1390 C CG2 . ILE A 1 327 ? 137.918 122.704 162.593 1.00 25.31 ? 327 ILE A CG2 1 
ATOM   1391 C CD1 . ILE A 1 327 ? 137.486 119.659 161.836 1.00 43.18 ? 327 ILE A CD1 1 
ATOM   1392 N N   . VAL A 1 328 ? 134.991 124.723 162.018 1.00 27.74 ? 328 VAL A N   1 
ATOM   1393 C CA  . VAL A 1 328 ? 135.009 126.164 161.798 1.00 23.69 ? 328 VAL A CA  1 
ATOM   1394 C C   . VAL A 1 328 ? 134.194 126.883 162.866 1.00 32.18 ? 328 VAL A C   1 
ATOM   1395 O O   . VAL A 1 328 ? 134.628 127.904 163.410 1.00 35.28 ? 328 VAL A O   1 
ATOM   1396 C CB  . VAL A 1 328 ? 134.506 126.480 160.378 1.00 24.87 ? 328 VAL A CB  1 
ATOM   1397 C CG1 . VAL A 1 328 ? 134.156 127.955 160.229 1.00 30.67 ? 328 VAL A CG1 1 
ATOM   1398 C CG2 . VAL A 1 328 ? 135.557 126.072 159.355 1.00 28.67 ? 328 VAL A CG2 1 
ATOM   1399 N N   . PHE A 1 329 ? 133.000 126.375 163.178 1.00 32.32 ? 329 PHE A N   1 
ATOM   1400 C CA  . PHE A 1 329 ? 132.175 127.016 164.197 1.00 29.37 ? 329 PHE A CA  1 
ATOM   1401 C C   . PHE A 1 329 ? 132.771 126.865 165.588 1.00 34.54 ? 329 PHE A C   1 
ATOM   1402 O O   . PHE A 1 329 ? 132.688 127.795 166.398 1.00 36.54 ? 329 PHE A O   1 
ATOM   1403 C CB  . PHE A 1 329 ? 130.762 126.442 164.175 1.00 22.83 ? 329 PHE A CB  1 
ATOM   1404 C CG  . PHE A 1 329 ? 129.828 127.108 165.141 1.00 35.85 ? 329 PHE A CG  1 
ATOM   1405 C CD1 . PHE A 1 329 ? 129.323 128.366 164.875 1.00 38.29 ? 329 PHE A CD1 1 
ATOM   1406 C CD2 . PHE A 1 329 ? 129.447 126.475 166.310 1.00 36.17 ? 329 PHE A CD2 1 
ATOM   1407 C CE1 . PHE A 1 329 ? 128.463 128.983 165.758 1.00 34.38 ? 329 PHE A CE1 1 
ATOM   1408 C CE2 . PHE A 1 329 ? 128.582 127.088 167.196 1.00 33.35 ? 329 PHE A CE2 1 
ATOM   1409 C CZ  . PHE A 1 329 ? 128.091 128.343 166.919 1.00 33.22 ? 329 PHE A CZ  1 
ATOM   1410 N N   . PHE A 1 330 ? 133.352 125.704 165.896 1.00 34.15 ? 330 PHE A N   1 
ATOM   1411 C CA  . PHE A 1 330 ? 133.923 125.502 167.222 1.00 27.05 ? 330 PHE A CA  1 
ATOM   1412 C C   . PHE A 1 330 ? 135.132 126.395 167.452 1.00 29.76 ? 330 PHE A C   1 
ATOM   1413 O O   . PHE A 1 330 ? 135.318 126.906 168.560 1.00 39.65 ? 330 PHE A O   1 
ATOM   1414 C CB  . PHE A 1 330 ? 134.305 124.036 167.415 1.00 34.69 ? 330 PHE A CB  1 
ATOM   1415 C CG  . PHE A 1 330 ? 135.368 123.813 168.455 1.00 45.68 ? 330 PHE A CG  1 
ATOM   1416 C CD1 . PHE A 1 330 ? 135.075 123.937 169.803 1.00 44.76 ? 330 PHE A CD1 1 
ATOM   1417 C CD2 . PHE A 1 330 ? 136.656 123.464 168.086 1.00 42.37 ? 330 PHE A CD2 1 
ATOM   1418 C CE1 . PHE A 1 330 ? 136.048 123.727 170.760 1.00 36.26 ? 330 PHE A CE1 1 
ATOM   1419 C CE2 . PHE A 1 330 ? 137.631 123.254 169.040 1.00 43.25 ? 330 PHE A CE2 1 
ATOM   1420 C CZ  . PHE A 1 330 ? 137.327 123.386 170.378 1.00 39.91 ? 330 PHE A CZ  1 
ATOM   1421 N N   . LEU A 1 331 ? 135.967 126.592 166.431 1.00 28.00 ? 331 LEU A N   1 
ATOM   1422 C CA  . LEU A 1 331 ? 137.177 127.382 166.626 1.00 25.03 ? 331 LEU A CA  1 
ATOM   1423 C C   . LEU A 1 331 ? 136.866 128.864 166.771 1.00 31.66 ? 331 LEU A C   1 
ATOM   1424 O O   . LEU A 1 331 ? 137.510 129.549 167.570 1.00 38.61 ? 331 LEU A O   1 
ATOM   1425 C CB  . LEU A 1 331 ? 138.147 127.161 165.466 1.00 25.68 ? 331 LEU A CB  1 
ATOM   1426 C CG  . LEU A 1 331 ? 139.066 125.940 165.558 1.00 31.40 ? 331 LEU A CG  1 
ATOM   1427 C CD1 . LEU A 1 331 ? 139.838 125.790 164.266 1.00 35.61 ? 331 LEU A CD1 1 
ATOM   1428 C CD2 . LEU A 1 331 ? 140.027 126.022 166.734 1.00 27.53 ? 331 LEU A CD2 1 
ATOM   1429 N N   . PHE A 1 332 ? 135.895 129.378 166.016 1.00 27.67 ? 332 PHE A N   1 
ATOM   1430 C CA  . PHE A 1 332 ? 135.524 130.782 166.157 1.00 26.76 ? 332 PHE A CA  1 
ATOM   1431 C C   . PHE A 1 332 ? 134.979 131.069 167.547 1.00 30.75 ? 332 PHE A C   1 
ATOM   1432 O O   . PHE A 1 332 ? 135.291 132.106 168.140 1.00 39.86 ? 332 PHE A O   1 
ATOM   1433 C CB  . PHE A 1 332 ? 134.492 131.163 165.102 1.00 29.66 ? 332 PHE A CB  1 
ATOM   1434 C CG  . PHE A 1 332 ? 133.815 132.477 165.365 1.00 25.67 ? 332 PHE A CG  1 
ATOM   1435 C CD1 . PHE A 1 332 ? 134.462 133.667 165.098 1.00 25.93 ? 332 PHE A CD1 1 
ATOM   1436 C CD2 . PHE A 1 332 ? 132.532 132.522 165.875 1.00 31.31 ? 332 PHE A CD2 1 
ATOM   1437 C CE1 . PHE A 1 332 ? 133.843 134.872 165.335 1.00 33.19 ? 332 PHE A CE1 1 
ATOM   1438 C CE2 . PHE A 1 332 ? 131.912 133.728 166.118 1.00 27.33 ? 332 PHE A CE2 1 
ATOM   1439 C CZ  . PHE A 1 332 ? 132.567 134.902 165.845 1.00 24.71 ? 332 PHE A CZ  1 
ATOM   1440 N N   . VAL A 1 333 ? 134.152 130.170 168.079 1.00 30.77 ? 333 VAL A N   1 
ATOM   1441 C CA  . VAL A 1 333 ? 133.602 130.376 169.413 1.00 34.10 ? 333 VAL A CA  1 
ATOM   1442 C C   . VAL A 1 333 ? 134.703 130.274 170.461 1.00 32.43 ? 333 VAL A C   1 
ATOM   1443 O O   . VAL A 1 333 ? 134.837 131.143 171.326 1.00 37.60 ? 333 VAL A O   1 
ATOM   1444 C CB  . VAL A 1 333 ? 132.465 129.373 169.682 1.00 26.67 ? 333 VAL A CB  1 
ATOM   1445 C CG1 . VAL A 1 333 ? 132.087 129.355 171.158 1.00 27.18 ? 333 VAL A CG1 1 
ATOM   1446 C CG2 . VAL A 1 333 ? 131.258 129.706 168.830 1.00 22.74 ? 333 VAL A CG2 1 
ATOM   1447 N N   . VAL A 1 334 ? 135.529 129.228 170.388 1.00 29.81 ? 334 VAL A N   1 
ATOM   1448 C CA  . VAL A 1 334 ? 136.493 128.984 171.459 1.00 30.40 ? 334 VAL A CA  1 
ATOM   1449 C C   . VAL A 1 334 ? 137.643 129.976 171.478 1.00 35.56 ? 334 VAL A C   1 
ATOM   1450 O O   . VAL A 1 334 ? 138.335 130.068 172.497 1.00 36.73 ? 334 VAL A O   1 
ATOM   1451 C CB  . VAL A 1 334 ? 137.052 127.549 171.374 1.00 35.91 ? 334 VAL A CB  1 
ATOM   1452 C CG1 . VAL A 1 334 ? 138.198 127.445 170.370 1.00 35.57 ? 334 VAL A CG1 1 
ATOM   1453 C CG2 . VAL A 1 334 ? 137.505 127.074 172.745 1.00 38.91 ? 334 VAL A CG2 1 
ATOM   1454 N N   . MET A 1 335 ? 137.869 130.724 170.393 1.00 35.73 ? 335 MET A N   1 
ATOM   1455 C CA  . MET A 1 335 ? 138.999 131.642 170.305 1.00 40.12 ? 335 MET A CA  1 
ATOM   1456 C C   . MET A 1 335 ? 138.612 133.109 170.414 1.00 41.99 ? 335 MET A C   1 
ATOM   1457 O O   . MET A 1 335 ? 139.484 133.930 170.713 1.00 49.70 ? 335 MET A O   1 
ATOM   1458 C CB  . MET A 1 335 ? 139.760 131.429 168.990 1.00 33.87 ? 335 MET A CB  1 
ATOM   1459 C CG  . MET A 1 335 ? 140.732 130.266 169.040 1.00 36.64 ? 335 MET A CG  1 
ATOM   1460 S SD  . MET A 1 335 ? 141.636 130.025 167.506 1.00 47.97 ? 335 MET A SD  1 
ATOM   1461 C CE  . MET A 1 335 ? 143.068 129.141 168.112 1.00 38.66 ? 335 MET A CE  1 
ATOM   1462 N N   . TRP A 1 336 ? 137.348 133.460 170.189 1.00 36.97 ? 336 TRP A N   1 
ATOM   1463 C CA  . TRP A 1 336 ? 136.877 134.833 170.327 1.00 32.64 ? 336 TRP A CA  1 
ATOM   1464 C C   . TRP A 1 336 ? 135.921 135.020 171.490 1.00 38.45 ? 336 TRP A C   1 
ATOM   1465 O O   . TRP A 1 336 ? 135.977 136.052 172.159 1.00 42.33 ? 336 TRP A O   1 
ATOM   1466 C CB  . TRP A 1 336 ? 136.189 135.299 169.034 1.00 28.62 ? 336 TRP A CB  1 
ATOM   1467 C CG  . TRP A 1 336 ? 137.116 135.925 168.027 1.00 34.39 ? 336 TRP A CG  1 
ATOM   1468 C CD1 . TRP A 1 336 ? 137.294 135.537 166.733 1.00 32.01 ? 336 TRP A CD1 1 
ATOM   1469 C CD2 . TRP A 1 336 ? 137.985 137.049 168.230 1.00 40.65 ? 336 TRP A CD2 1 
ATOM   1470 N NE1 . TRP A 1 336 ? 138.217 136.344 166.118 1.00 32.70 ? 336 TRP A NE1 1 
ATOM   1471 C CE2 . TRP A 1 336 ? 138.657 137.279 167.016 1.00 40.87 ? 336 TRP A CE2 1 
ATOM   1472 C CE3 . TRP A 1 336 ? 138.261 137.879 169.321 1.00 35.66 ? 336 TRP A CE3 1 
ATOM   1473 C CZ2 . TRP A 1 336 ? 139.586 138.302 166.862 1.00 36.82 ? 336 TRP A CZ2 1 
ATOM   1474 C CZ3 . TRP A 1 336 ? 139.183 138.891 169.167 1.00 33.60 ? 336 TRP A CZ3 1 
ATOM   1475 C CH2 . TRP A 1 336 ? 139.835 139.095 167.948 1.00 36.17 ? 336 TRP A CH2 1 
ATOM   1476 N N   . CYS A 1 337 ? 135.045 134.056 171.751 1.00 33.20 ? 337 CYS A N   1 
ATOM   1477 C CA  . CYS A 1 337 ? 134.098 134.162 172.856 1.00 29.93 ? 337 CYS A CA  1 
ATOM   1478 C C   . CYS A 1 337 ? 134.781 134.335 174.212 1.00 38.71 ? 337 CYS A C   1 
ATOM   1479 O O   . CYS A 1 337 ? 134.287 135.133 175.016 1.00 42.14 ? 337 CYS A O   1 
ATOM   1480 C CB  . CYS A 1 337 ? 133.166 132.952 172.897 1.00 28.24 ? 337 CYS A CB  1 
ATOM   1481 S SG  . CYS A 1 337 ? 131.571 133.296 173.654 1.00 43.24 ? 337 CYS A SG  1 
ATOM   1482 N N   . PRO A 1 338 ? 135.877 133.621 174.532 1.00 36.11 ? 338 PRO A N   1 
ATOM   1483 C CA  . PRO A 1 338 ? 136.503 133.833 175.851 1.00 33.13 ? 338 PRO A CA  1 
ATOM   1484 C C   . PRO A 1 338 ? 136.907 135.269 176.123 1.00 37.51 ? 338 PRO A C   1 
ATOM   1485 O O   . PRO A 1 338 ? 136.776 135.738 177.259 1.00 45.54 ? 338 PRO A O   1 
ATOM   1486 C CB  . PRO A 1 338 ? 137.729 132.915 175.804 1.00 36.32 ? 338 PRO A CB  1 
ATOM   1487 C CG  . PRO A 1 338 ? 137.355 131.850 174.907 1.00 35.97 ? 338 PRO A CG  1 
ATOM   1488 C CD  . PRO A 1 338 ? 136.503 132.478 173.842 1.00 36.20 ? 338 PRO A CD  1 
ATOM   1489 N N   . PHE A 1 339 ? 137.396 135.987 175.115 1.00 38.67 ? 339 PHE A N   1 
ATOM   1490 C CA  . PHE A 1 339 ? 137.757 137.381 175.334 1.00 42.64 ? 339 PHE A CA  1 
ATOM   1491 C C   . PHE A 1 339 ? 136.524 138.247 175.561 1.00 37.57 ? 339 PHE A C   1 
ATOM   1492 O O   . PHE A 1 339 ? 136.544 139.147 176.406 1.00 40.95 ? 339 PHE A O   1 
ATOM   1493 C CB  . PHE A 1 339 ? 138.564 137.911 174.150 1.00 38.52 ? 339 PHE A CB  1 
ATOM   1494 C CG  . PHE A 1 339 ? 138.706 139.402 174.141 1.00 34.76 ? 339 PHE A CG  1 
ATOM   1495 C CD1 . PHE A 1 339 ? 139.560 140.033 175.021 1.00 32.46 ? 339 PHE A CD1 1 
ATOM   1496 C CD2 . PHE A 1 339 ? 137.972 140.175 173.262 1.00 37.88 ? 339 PHE A CD2 1 
ATOM   1497 C CE1 . PHE A 1 339 ? 139.683 141.402 175.017 1.00 35.96 ? 339 PHE A CE1 1 
ATOM   1498 C CE2 . PHE A 1 339 ? 138.091 141.543 173.261 1.00 41.85 ? 339 PHE A CE2 1 
ATOM   1499 C CZ  . PHE A 1 339 ? 138.946 142.156 174.140 1.00 37.40 ? 339 PHE A CZ  1 
ATOM   1500 N N   . PHE A 1 340 ? 135.445 137.996 174.822 1.00 26.31 ? 340 PHE A N   1 
ATOM   1501 C CA  . PHE A 1 340 ? 134.291 138.885 174.861 1.00 27.72 ? 340 PHE A CA  1 
ATOM   1502 C C   . PHE A 1 340 ? 133.414 138.696 176.093 1.00 34.63 ? 340 PHE A C   1 
ATOM   1503 O O   . PHE A 1 340 ? 132.738 139.649 176.492 1.00 41.28 ? 340 PHE A O   1 
ATOM   1504 C CB  . PHE A 1 340 ? 133.454 138.711 173.595 1.00 29.73 ? 340 PHE A CB  1 
ATOM   1505 C CG  . PHE A 1 340 ? 133.939 139.538 172.440 1.00 31.63 ? 340 PHE A CG  1 
ATOM   1506 C CD1 . PHE A 1 340 ? 134.903 139.051 171.578 1.00 33.80 ? 340 PHE A CD1 1 
ATOM   1507 C CD2 . PHE A 1 340 ? 133.436 140.806 172.221 1.00 32.53 ? 340 PHE A CD2 1 
ATOM   1508 C CE1 . PHE A 1 340 ? 135.351 139.810 170.521 1.00 34.48 ? 340 PHE A CE1 1 
ATOM   1509 C CE2 . PHE A 1 340 ? 133.881 141.566 171.165 1.00 31.94 ? 340 PHE A CE2 1 
ATOM   1510 C CZ  . PHE A 1 340 ? 134.839 141.067 170.315 1.00 36.66 ? 340 PHE A CZ  1 
ATOM   1511 N N   . ILE A 1 341 ? 133.377 137.504 176.696 1.00 39.10 ? 341 ILE A N   1 
ATOM   1512 C CA  . ILE A 1 341 ? 132.678 137.383 177.976 1.00 39.65 ? 341 ILE A CA  1 
ATOM   1513 C C   . ILE A 1 341 ? 133.473 138.082 179.071 1.00 40.71 ? 341 ILE A C   1 
ATOM   1514 O O   . ILE A 1 341 ? 132.903 138.756 179.936 1.00 44.47 ? 341 ILE A O   1 
ATOM   1515 C CB  . ILE A 1 341 ? 132.381 135.913 178.347 1.00 42.82 ? 341 ILE A CB  1 
ATOM   1516 C CG1 . ILE A 1 341 ? 133.598 134.991 178.196 1.00 45.35 ? 341 ILE A CG1 1 
ATOM   1517 C CG2 . ILE A 1 341 ? 131.238 135.382 177.492 1.00 41.99 ? 341 ILE A CG2 1 
ATOM   1518 C CD1 . ILE A 1 341 ? 133.548 133.767 179.092 1.00 44.41 ? 341 ILE A CD1 1 
ATOM   1519 N N   . THR A 1 342 ? 134.801 137.948 179.048 1.00 39.59 ? 342 THR A N   1 
ATOM   1520 C CA  . THR A 1 342 ? 135.627 138.629 180.038 1.00 43.40 ? 342 THR A CA  1 
ATOM   1521 C C   . THR A 1 342 ? 135.596 140.138 179.842 1.00 44.76 ? 342 THR A C   1 
ATOM   1522 O O   . THR A 1 342 ? 135.622 140.889 180.823 1.00 46.28 ? 342 THR A O   1 
ATOM   1523 C CB  . THR A 1 342 ? 137.070 138.124 179.965 1.00 39.91 ? 342 THR A CB  1 
ATOM   1524 O OG1 . THR A 1 342 ? 137.084 136.695 179.888 1.00 36.17 ? 342 THR A OG1 1 
ATOM   1525 C CG2 . THR A 1 342 ? 137.853 138.558 181.189 1.00 45.00 ? 342 THR A CG2 1 
ATOM   1526 N N   . ASN A 1 343 ? 135.544 140.594 178.589 1.00 40.68 ? 343 ASN A N   1 
ATOM   1527 C CA  . ASN A 1 343 ? 135.521 142.026 178.310 1.00 34.80 ? 343 ASN A CA  1 
ATOM   1528 C C   . ASN A 1 343 ? 134.275 142.684 178.885 1.00 35.68 ? 343 ASN A C   1 
ATOM   1529 O O   . ASN A 1 343 ? 134.354 143.781 179.448 1.00 37.19 ? 343 ASN A O   1 
ATOM   1530 C CB  . ASN A 1 343 ? 135.597 142.259 176.803 1.00 37.97 ? 343 ASN A CB  1 
ATOM   1531 C CG  . ASN A 1 343 ? 136.052 143.655 176.449 1.00 41.69 ? 343 ASN A CG  1 
ATOM   1532 O OD1 . ASN A 1 343 ? 136.099 144.539 177.300 1.00 45.57 ? 343 ASN A OD1 1 
ATOM   1533 N ND2 . ASN A 1 343 ? 136.391 143.863 175.183 1.00 34.73 ? 343 ASN A ND2 1 
ATOM   1534 N N   . ILE A 1 344 ? 133.121 142.028 178.760 1.00 39.37 ? 344 ILE A N   1 
ATOM   1535 C CA  . ILE A 1 344 ? 131.851 142.620 179.166 1.00 42.21 ? 344 ILE A CA  1 
ATOM   1536 C C   . ILE A 1 344 ? 131.473 142.295 180.609 1.00 48.67 ? 344 ILE A C   1 
ATOM   1537 O O   . ILE A 1 344 ? 130.814 143.119 181.260 1.00 56.60 ? 344 ILE A O   1 
ATOM   1538 C CB  . ILE A 1 344 ? 130.727 142.196 178.189 1.00 43.85 ? 344 ILE A CB  1 
ATOM   1539 C CG1 . ILE A 1 344 ? 129.721 143.332 177.967 1.00 42.91 ? 344 ILE A CG1 1 
ATOM   1540 C CG2 . ILE A 1 344 ? 130.001 140.921 178.642 1.00 46.95 ? 344 ILE A CG2 1 
ATOM   1541 C CD1 . ILE A 1 344 ? 128.913 143.164 176.709 1.00 48.58 ? 344 ILE A CD1 1 
ATOM   1542 N N   . MET A 1 345 ? 131.865 141.130 181.130 1.00 48.01 ? 345 MET A N   1 
ATOM   1543 C CA  . MET A 1 345 ? 131.610 140.838 182.536 1.00 45.33 ? 345 MET A CA  1 
ATOM   1544 C C   . MET A 1 345 ? 132.396 141.762 183.453 1.00 51.06 ? 345 MET A C   1 
ATOM   1545 O O   . MET A 1 345 ? 131.903 142.128 184.525 1.00 48.15 ? 345 MET A O   1 
ATOM   1546 C CB  . MET A 1 345 ? 131.952 139.381 182.853 1.00 44.53 ? 345 MET A CB  1 
ATOM   1547 C CG  . MET A 1 345 ? 130.985 138.362 182.245 1.00 50.49 ? 345 MET A CG  1 
ATOM   1548 S SD  . MET A 1 345 ? 129.344 138.178 183.000 1.00 64.59 ? 345 MET A SD  1 
ATOM   1549 C CE  . MET A 1 345 ? 129.615 138.479 184.747 1.00 49.58 ? 345 MET A CE  1 
ATOM   1550 N N   . ALA A 1 346 ? 133.610 142.147 183.052 1.00 57.44 ? 346 ALA A N   1 
ATOM   1551 C CA  . ALA A 1 346 ? 134.398 143.076 183.856 1.00 54.83 ? 346 ALA A CA  1 
ATOM   1552 C C   . ALA A 1 346 ? 133.700 144.424 183.980 1.00 57.43 ? 346 ALA A C   1 
ATOM   1553 O O   . ALA A 1 346 ? 133.751 145.060 185.039 1.00 56.18 ? 346 ALA A O   1 
ATOM   1554 C CB  . ALA A 1 346 ? 135.788 143.245 183.246 1.00 47.61 ? 346 ALA A CB  1 
ATOM   1555 N N   . VAL A 1 347 ? 133.049 144.878 182.915 1.00 57.65 ? 347 VAL A N   1 
ATOM   1556 C CA  . VAL A 1 347 ? 132.338 146.147 182.941 1.00 56.18 ? 347 VAL A CA  1 
ATOM   1557 C C   . VAL A 1 347 ? 131.309 146.187 181.817 1.00 54.14 ? 347 VAL A C   1 
ATOM   1558 O O   . VAL A 1 347 ? 130.520 147.125 181.715 1.00 52.35 ? 347 VAL A O   1 
ATOM   1559 C CB  . VAL A 1 347 ? 133.323 147.331 182.840 1.00 64.62 ? 347 VAL A CB  1 
ATOM   1560 C CG1 . VAL A 1 347 ? 133.804 147.524 181.404 1.00 62.12 ? 347 VAL A CG1 1 
ATOM   1561 C CG2 . VAL A 1 347 ? 132.688 148.606 183.377 1.00 64.84 ? 347 VAL A CG2 1 
ATOM   1562 N N   . ASN A 1 354 ? 138.496 140.599 191.736 1.00 62.35 ? 354 ASN A N   1 
ATOM   1563 C CA  . ASN A 1 354 ? 139.872 141.070 191.834 1.00 60.45 ? 354 ASN A CA  1 
ATOM   1564 C C   . ASN A 1 354 ? 140.357 141.577 190.482 1.00 60.99 ? 354 ASN A C   1 
ATOM   1565 O O   . ASN A 1 354 ? 140.251 140.880 189.475 1.00 55.54 ? 354 ASN A O   1 
ATOM   1566 C CB  . ASN A 1 354 ? 140.788 139.954 192.341 1.00 53.95 ? 354 ASN A CB  1 
ATOM   1567 N N   . GLU A 1 355 ? 140.887 142.800 190.466 1.00 65.27 ? 355 GLU A N   1 
ATOM   1568 C CA  . GLU A 1 355 ? 141.364 143.385 189.219 1.00 62.71 ? 355 GLU A CA  1 
ATOM   1569 C C   . GLU A 1 355 ? 142.567 142.639 188.661 1.00 60.57 ? 355 GLU A C   1 
ATOM   1570 O O   . GLU A 1 355 ? 142.669 142.465 187.442 1.00 58.43 ? 355 GLU A O   1 
ATOM   1571 C CB  . GLU A 1 355 ? 141.718 144.857 189.432 1.00 60.36 ? 355 GLU A CB  1 
ATOM   1572 N N   . ASP A 1 356 ? 143.481 142.196 189.528 1.00 64.73 ? 356 ASP A N   1 
ATOM   1573 C CA  . ASP A 1 356 ? 144.690 141.527 189.058 1.00 64.83 ? 356 ASP A CA  1 
ATOM   1574 C C   . ASP A 1 356 ? 144.369 140.229 188.331 1.00 64.26 ? 356 ASP A C   1 
ATOM   1575 O O   . ASP A 1 356 ? 145.015 139.908 187.326 1.00 61.27 ? 356 ASP A O   1 
ATOM   1576 C CB  . ASP A 1 356 ? 145.628 141.255 190.233 1.00 57.61 ? 356 ASP A CB  1 
ATOM   1577 N N   . VAL A 1 357 ? 143.392 139.467 188.823 1.00 58.57 ? 357 VAL A N   1 
ATOM   1578 C CA  . VAL A 1 357 ? 143.010 138.228 188.154 1.00 56.89 ? 357 VAL A CA  1 
ATOM   1579 C C   . VAL A 1 357 ? 142.386 138.529 186.797 1.00 54.60 ? 357 VAL A C   1 
ATOM   1580 O O   . VAL A 1 357 ? 142.755 137.929 185.781 1.00 54.64 ? 357 VAL A O   1 
ATOM   1581 C CB  . VAL A 1 357 ? 142.060 137.409 189.047 1.00 59.91 ? 357 VAL A CB  1 
ATOM   1582 C CG1 . VAL A 1 357 ? 141.484 136.228 188.278 1.00 57.88 ? 357 VAL A CG1 1 
ATOM   1583 C CG2 . VAL A 1 357 ? 142.792 136.928 190.293 1.00 60.38 ? 357 VAL A CG2 1 
ATOM   1584 N N   . ILE A 1 358 ? 141.435 139.464 186.757 1.00 54.67 ? 358 ILE A N   1 
ATOM   1585 C CA  . ILE A 1 358 ? 140.803 139.821 185.491 1.00 53.84 ? 358 ILE A CA  1 
ATOM   1586 C C   . ILE A 1 358 ? 141.791 140.505 184.557 1.00 53.11 ? 358 ILE A C   1 
ATOM   1587 O O   . ILE A 1 358 ? 141.693 140.340 183.336 1.00 50.50 ? 358 ILE A O   1 
ATOM   1588 C CB  . ILE A 1 358 ? 139.565 140.705 185.746 1.00 58.79 ? 358 ILE A CB  1 
ATOM   1589 C CG1 . ILE A 1 358 ? 138.331 139.849 186.056 1.00 56.65 ? 358 ILE A CG1 1 
ATOM   1590 C CG2 . ILE A 1 358 ? 139.236 141.617 184.551 1.00 56.79 ? 358 ILE A CG2 1 
ATOM   1591 C CD1 . ILE A 1 358 ? 137.793 139.010 184.900 1.00 55.73 ? 358 ILE A CD1 1 
ATOM   1592 N N   . GLY A 1 359 ? 142.729 141.287 185.094 1.00 53.62 ? 359 GLY A N   1 
ATOM   1593 C CA  . GLY A 1 359 ? 143.756 141.875 184.255 1.00 52.21 ? 359 GLY A CA  1 
ATOM   1594 C C   . GLY A 1 359 ? 144.642 140.845 183.595 1.00 50.19 ? 359 GLY A C   1 
ATOM   1595 O O   . GLY A 1 359 ? 145.076 141.041 182.456 1.00 56.18 ? 359 GLY A O   1 
ATOM   1596 N N   . ALA A 1 360 ? 144.931 139.746 184.290 1.00 43.56 ? 360 ALA A N   1 
ATOM   1597 C CA  . ALA A 1 360 ? 145.677 138.658 183.675 1.00 51.95 ? 360 ALA A CA  1 
ATOM   1598 C C   . ALA A 1 360 ? 144.821 137.867 182.696 1.00 51.74 ? 360 ALA A C   1 
ATOM   1599 O O   . ALA A 1 360 ? 145.326 137.418 181.663 1.00 47.17 ? 360 ALA A O   1 
ATOM   1600 C CB  . ALA A 1 360 ? 146.232 137.725 184.750 1.00 53.08 ? 360 ALA A CB  1 
ATOM   1601 N N   . LEU A 1 361 ? 143.536 137.679 183.002 1.00 54.04 ? 361 LEU A N   1 
ATOM   1602 C CA  . LEU A 1 361 ? 142.669 136.930 182.099 1.00 43.48 ? 361 LEU A CA  1 
ATOM   1603 C C   . LEU A 1 361 ? 142.499 137.654 180.771 1.00 46.06 ? 361 LEU A C   1 
ATOM   1604 O O   . LEU A 1 361 ? 142.604 137.037 179.706 1.00 50.44 ? 361 LEU A O   1 
ATOM   1605 C CB  . LEU A 1 361 ? 141.305 136.699 182.750 1.00 40.83 ? 361 LEU A CB  1 
ATOM   1606 C CG  . LEU A 1 361 ? 141.151 135.591 183.796 1.00 47.30 ? 361 LEU A CG  1 
ATOM   1607 C CD1 . LEU A 1 361 ? 139.699 135.514 184.232 1.00 52.09 ? 361 LEU A CD1 1 
ATOM   1608 C CD2 . LEU A 1 361 ? 141.623 134.235 183.297 1.00 46.33 ? 361 LEU A CD2 1 
ATOM   1609 N N   . LEU A 1 362 ? 142.240 138.961 180.810 1.00 44.32 ? 362 LEU A N   1 
ATOM   1610 C CA  . LEU A 1 362 ? 142.081 139.712 179.571 1.00 38.29 ? 362 LEU A CA  1 
ATOM   1611 C C   . LEU A 1 362 ? 143.378 139.801 178.784 1.00 39.68 ? 362 LEU A C   1 
ATOM   1612 O O   . LEU A 1 362 ? 143.338 140.012 177.569 1.00 42.76 ? 362 LEU A O   1 
ATOM   1613 C CB  . LEU A 1 362 ? 141.572 141.127 179.861 1.00 40.02 ? 362 LEU A CB  1 
ATOM   1614 C CG  . LEU A 1 362 ? 140.072 141.439 179.835 1.00 44.09 ? 362 LEU A CG  1 
ATOM   1615 C CD1 . LEU A 1 362 ? 139.871 142.940 179.946 1.00 42.33 ? 362 LEU A CD1 1 
ATOM   1616 C CD2 . LEU A 1 362 ? 139.381 140.923 178.588 1.00 41.77 ? 362 LEU A CD2 1 
ATOM   1617 N N   . ASN A 1 363 ? 144.525 139.658 179.443 1.00 43.77 ? 363 ASN A N   1 
ATOM   1618 C CA  . ASN A 1 363 ? 145.794 139.730 178.732 1.00 43.17 ? 363 ASN A CA  1 
ATOM   1619 C C   . ASN A 1 363 ? 145.992 138.506 177.850 1.00 43.90 ? 363 ASN A C   1 
ATOM   1620 O O   . ASN A 1 363 ? 146.359 138.627 176.676 1.00 48.07 ? 363 ASN A O   1 
ATOM   1621 C CB  . ASN A 1 363 ? 146.934 139.860 179.736 1.00 44.17 ? 363 ASN A CB  1 
ATOM   1622 C CG  . ASN A 1 363 ? 148.271 140.130 179.076 1.00 49.02 ? 363 ASN A CG  1 
ATOM   1623 O OD1 . ASN A 1 363 ? 148.484 141.193 178.495 1.00 50.18 ? 363 ASN A OD1 1 
ATOM   1624 N ND2 . ASN A 1 363 ? 149.182 139.167 179.163 1.00 54.30 ? 363 ASN A ND2 1 
ATOM   1625 N N   . VAL A 1 364 ? 145.755 137.313 178.399 1.00 39.65 ? 364 VAL A N   1 
ATOM   1626 C CA  . VAL A 1 364 ? 145.957 136.094 177.622 1.00 44.01 ? 364 VAL A CA  1 
ATOM   1627 C C   . VAL A 1 364 ? 144.852 135.919 176.591 1.00 42.08 ? 364 VAL A C   1 
ATOM   1628 O O   . VAL A 1 364 ? 145.117 135.504 175.458 1.00 43.45 ? 364 VAL A O   1 
ATOM   1629 C CB  . VAL A 1 364 ? 146.057 134.864 178.545 1.00 47.82 ? 364 VAL A CB  1 
ATOM   1630 C CG1 . VAL A 1 364 ? 146.524 133.647 177.753 1.00 44.74 ? 364 VAL A CG1 1 
ATOM   1631 C CG2 . VAL A 1 364 ? 147.009 135.136 179.700 1.00 45.67 ? 364 VAL A CG2 1 
ATOM   1632 N N   . PHE A 1 365 ? 143.603 136.216 176.953 1.00 37.61 ? 365 PHE A N   1 
ATOM   1633 C CA  . PHE A 1 365 ? 142.501 136.007 176.021 1.00 35.82 ? 365 PHE A CA  1 
ATOM   1634 C C   . PHE A 1 365 ? 142.593 136.915 174.805 1.00 40.50 ? 365 PHE A C   1 
ATOM   1635 O O   . PHE A 1 365 ? 142.064 136.560 173.748 1.00 39.00 ? 365 PHE A O   1 
ATOM   1636 C CB  . PHE A 1 365 ? 141.150 136.236 176.707 1.00 42.72 ? 365 PHE A CB  1 
ATOM   1637 C CG  . PHE A 1 365 ? 140.823 135.261 177.821 1.00 42.63 ? 365 PHE A CG  1 
ATOM   1638 C CD1 . PHE A 1 365 ? 141.565 134.107 178.042 1.00 37.24 ? 365 PHE A CD1 1 
ATOM   1639 C CD2 . PHE A 1 365 ? 139.732 135.504 178.636 1.00 38.97 ? 365 PHE A CD2 1 
ATOM   1640 C CE1 . PHE A 1 365 ? 141.235 133.243 179.059 1.00 41.05 ? 365 PHE A CE1 1 
ATOM   1641 C CE2 . PHE A 1 365 ? 139.401 134.639 179.649 1.00 39.28 ? 365 PHE A CE2 1 
ATOM   1642 C CZ  . PHE A 1 365 ? 140.151 133.507 179.860 1.00 44.56 ? 365 PHE A CZ  1 
ATOM   1643 N N   . VAL A 1 366 ? 143.237 138.075 174.930 1.00 38.90 ? 366 VAL A N   1 
ATOM   1644 C CA  . VAL A 1 366 ? 143.440 138.935 173.769 1.00 31.51 ? 366 VAL A CA  1 
ATOM   1645 C C   . VAL A 1 366 ? 144.298 138.220 172.736 1.00 30.62 ? 366 VAL A C   1 
ATOM   1646 O O   . VAL A 1 366 ? 143.994 138.233 171.539 1.00 38.60 ? 366 VAL A O   1 
ATOM   1647 C CB  . VAL A 1 366 ? 144.062 140.276 174.202 1.00 32.98 ? 366 VAL A CB  1 
ATOM   1648 C CG1 . VAL A 1 366 ? 144.759 140.980 173.041 1.00 35.96 ? 366 VAL A CG1 1 
ATOM   1649 C CG2 . VAL A 1 366 ? 142.999 141.178 174.785 1.00 36.88 ? 366 VAL A CG2 1 
ATOM   1650 N N   . TRP A 1 367 ? 145.376 137.579 173.185 1.00 28.47 ? 367 TRP A N   1 
ATOM   1651 C CA  . TRP A 1 367 ? 146.264 136.884 172.264 1.00 28.82 ? 367 TRP A CA  1 
ATOM   1652 C C   . TRP A 1 367 ? 145.655 135.598 171.727 1.00 35.98 ? 367 TRP A C   1 
ATOM   1653 O O   . TRP A 1 367 ? 146.081 135.123 170.671 1.00 34.76 ? 367 TRP A O   1 
ATOM   1654 C CB  . TRP A 1 367 ? 147.591 136.592 172.954 1.00 26.26 ? 367 TRP A CB  1 
ATOM   1655 C CG  . TRP A 1 367 ? 148.493 137.769 172.943 1.00 37.43 ? 367 TRP A CG  1 
ATOM   1656 C CD1 . TRP A 1 367 ? 148.803 138.574 173.996 1.00 41.53 ? 367 TRP A CD1 1 
ATOM   1657 C CD2 . TRP A 1 367 ? 149.200 138.291 171.815 1.00 38.79 ? 367 TRP A CD2 1 
ATOM   1658 N NE1 . TRP A 1 367 ? 149.663 139.565 173.596 1.00 45.48 ? 367 TRP A NE1 1 
ATOM   1659 C CE2 . TRP A 1 367 ? 149.923 139.412 172.260 1.00 43.69 ? 367 TRP A CE2 1 
ATOM   1660 C CE3 . TRP A 1 367 ? 149.293 137.918 170.473 1.00 34.48 ? 367 TRP A CE3 1 
ATOM   1661 C CZ2 . TRP A 1 367 ? 150.730 140.160 171.411 1.00 34.26 ? 367 TRP A CZ2 1 
ATOM   1662 C CZ3 . TRP A 1 367 ? 150.092 138.662 169.634 1.00 36.79 ? 367 TRP A CZ3 1 
ATOM   1663 C CH2 . TRP A 1 367 ? 150.801 139.771 170.105 1.00 30.52 ? 367 TRP A CH2 1 
ATOM   1664 N N   . ILE A 1 368 ? 144.681 135.017 172.429 1.00 45.35 ? 368 ILE A N   1 
ATOM   1665 C CA  . ILE A 1 368 ? 143.934 133.900 171.862 1.00 38.97 ? 368 ILE A CA  1 
ATOM   1666 C C   . ILE A 1 368 ? 143.052 134.391 170.720 1.00 37.89 ? 368 ILE A C   1 
ATOM   1667 O O   . ILE A 1 368 ? 142.867 133.694 169.717 1.00 39.96 ? 368 ILE A O   1 
ATOM   1668 C CB  . ILE A 1 368 ? 143.123 133.192 172.963 1.00 37.05 ? 368 ILE A CB  1 
ATOM   1669 C CG1 . ILE A 1 368 ? 144.060 132.333 173.817 1.00 40.58 ? 368 ILE A CG1 1 
ATOM   1670 C CG2 . ILE A 1 368 ? 142.021 132.316 172.358 1.00 35.03 ? 368 ILE A CG2 1 
ATOM   1671 C CD1 . ILE A 1 368 ? 143.465 131.869 175.131 1.00 44.73 ? 368 ILE A CD1 1 
ATOM   1672 N N   . GLY A 1 369 ? 142.485 135.590 170.856 1.00 27.97 ? 369 GLY A N   1 
ATOM   1673 C CA  . GLY A 1 369 ? 141.740 136.171 169.755 1.00 24.34 ? 369 GLY A CA  1 
ATOM   1674 C C   . GLY A 1 369 ? 142.609 136.483 168.555 1.00 26.06 ? 369 GLY A C   1 
ATOM   1675 O O   . GLY A 1 369 ? 142.209 136.238 167.415 1.00 34.75 ? 369 GLY A O   1 
ATOM   1676 N N   . TYR A 1 370 ? 143.816 136.995 168.816 1.00 31.60 ? 370 TYR A N   1 
ATOM   1677 C CA  . TYR A 1 370 ? 144.772 137.288 167.714 1.00 28.41 ? 370 TYR A CA  1 
ATOM   1678 C C   . TYR A 1 370 ? 145.160 135.982 167.030 1.00 39.18 ? 370 TYR A C   1 
ATOM   1679 O O   . TYR A 1 370 ? 145.280 135.962 165.787 1.00 42.35 ? 370 TYR A O   1 
ATOM   1680 C CB  . TYR A 1 370 ? 146.034 137.970 168.248 1.00 23.19 ? 370 TYR A CB  1 
ATOM   1681 C CG  . TYR A 1 370 ? 145.865 139.400 168.742 1.00 28.37 ? 370 TYR A CG  1 
ATOM   1682 C CD1 . TYR A 1 370 ? 144.876 140.231 168.230 1.00 34.28 ? 370 TYR A CD1 1 
ATOM   1683 C CD2 . TYR A 1 370 ? 146.717 139.926 169.705 1.00 37.19 ? 370 TYR A CD2 1 
ATOM   1684 C CE1 . TYR A 1 370 ? 144.729 141.535 168.674 1.00 36.01 ? 370 TYR A CE1 1 
ATOM   1685 C CE2 . TYR A 1 370 ? 146.585 141.228 170.153 1.00 35.60 ? 370 TYR A CE2 1 
ATOM   1686 C CZ  . TYR A 1 370 ? 145.587 142.034 169.638 1.00 38.08 ? 370 TYR A CZ  1 
ATOM   1687 O OH  . TYR A 1 370 ? 145.457 143.316 170.087 1.00 43.48 ? 370 TYR A OH  1 
ATOM   1688 N N   . LEU A 1 371 ? 145.362 134.919 167.814 1.00 37.83 ? 371 LEU A N   1 
ATOM   1689 C CA  . LEU A 1 371 ? 145.798 133.649 167.247 1.00 27.48 ? 371 LEU A CA  1 
ATOM   1690 C C   . LEU A 1 371 ? 144.790 133.093 166.250 1.00 28.25 ? 371 LEU A C   1 
ATOM   1691 O O   . LEU A 1 371 ? 145.175 132.321 165.368 1.00 35.10 ? 371 LEU A O   1 
ATOM   1692 C CB  . LEU A 1 371 ? 146.052 132.640 168.371 1.00 33.50 ? 371 LEU A CB  1 
ATOM   1693 C CG  . LEU A 1 371 ? 146.209 131.153 168.041 1.00 33.32 ? 371 LEU A CG  1 
ATOM   1694 C CD1 . LEU A 1 371 ? 147.421 130.922 167.163 1.00 38.54 ? 371 LEU A CD1 1 
ATOM   1695 C CD2 . LEU A 1 371 ? 146.336 130.357 169.324 1.00 36.21 ? 371 LEU A CD2 1 
ATOM   1696 N N   . SER A 1 372 ? 143.514 133.463 166.370 1.00 37.94 ? 372 SER A N   1 
ATOM   1697 C CA  . SER A 1 372 ? 142.522 133.051 165.385 1.00 37.90 ? 372 SER A CA  1 
ATOM   1698 C C   . SER A 1 372 ? 142.763 133.683 164.021 1.00 36.29 ? 372 SER A C   1 
ATOM   1699 O O   . SER A 1 372 ? 142.257 133.168 163.020 1.00 35.31 ? 372 SER A O   1 
ATOM   1700 C CB  . SER A 1 372 ? 141.116 133.401 165.871 1.00 35.24 ? 372 SER A CB  1 
ATOM   1701 O OG  . SER A 1 372 ? 140.265 133.705 164.782 1.00 37.52 ? 372 SER A OG  1 
ATOM   1702 N N   . SER A 1 373 ? 143.507 134.790 163.954 1.00 35.67 ? 373 SER A N   1 
ATOM   1703 C CA  . SER A 1 373 ? 143.871 135.369 162.666 1.00 37.90 ? 373 SER A CA  1 
ATOM   1704 C C   . SER A 1 373 ? 144.986 134.596 161.976 1.00 40.43 ? 373 SER A C   1 
ATOM   1705 O O   . SER A 1 373 ? 145.170 134.753 160.765 1.00 37.43 ? 373 SER A O   1 
ATOM   1706 C CB  . SER A 1 373 ? 144.291 136.830 162.836 1.00 42.69 ? 373 SER A CB  1 
ATOM   1707 O OG  . SER A 1 373 ? 143.178 137.694 162.694 1.00 46.78 ? 373 SER A OG  1 
ATOM   1708 N N   . ALA A 1 374 ? 145.737 133.780 162.714 1.00 39.02 ? 374 ALA A N   1 
ATOM   1709 C CA  . ALA A 1 374 ? 146.690 132.859 162.110 1.00 35.37 ? 374 ALA A CA  1 
ATOM   1710 C C   . ALA A 1 374 ? 146.035 131.574 161.635 1.00 33.73 ? 374 ALA A C   1 
ATOM   1711 O O   . ALA A 1 374 ? 146.561 130.920 160.729 1.00 35.30 ? 374 ALA A O   1 
ATOM   1712 C CB  . ALA A 1 374 ? 147.797 132.511 163.106 1.00 34.41 ? 374 ALA A CB  1 
ATOM   1713 N N   . VAL A 1 375 ? 144.898 131.203 162.231 1.00 35.98 ? 375 VAL A N   1 
ATOM   1714 C CA  . VAL A 1 375 ? 144.246 129.939 161.903 1.00 30.89 ? 375 VAL A CA  1 
ATOM   1715 C C   . VAL A 1 375 ? 143.253 130.123 160.761 1.00 27.58 ? 375 VAL A C   1 
ATOM   1716 O O   . VAL A 1 375 ? 142.999 129.187 159.995 1.00 37.86 ? 375 VAL A O   1 
ATOM   1717 C CB  . VAL A 1 375 ? 143.574 129.360 163.163 1.00 32.76 ? 375 VAL A CB  1 
ATOM   1718 C CG1 . VAL A 1 375 ? 142.509 128.325 162.815 1.00 27.40 ? 375 VAL A CG1 1 
ATOM   1719 C CG2 . VAL A 1 375 ? 144.616 128.749 164.080 1.00 35.15 ? 375 VAL A CG2 1 
ATOM   1720 N N   . ASN A 1 376 ? 142.665 131.317 160.631 1.00 29.67 ? 376 ASN A N   1 
ATOM   1721 C CA  . ASN A 1 376 ? 141.612 131.560 159.648 1.00 39.57 ? 376 ASN A CA  1 
ATOM   1722 C C   . ASN A 1 376 ? 142.083 131.275 158.223 1.00 40.44 ? 376 ASN A C   1 
ATOM   1723 O O   . ASN A 1 376 ? 141.307 130.735 157.426 1.00 42.71 ? 376 ASN A O   1 
ATOM   1724 C CB  . ASN A 1 376 ? 141.084 132.995 159.757 1.00 43.42 ? 376 ASN A CB  1 
ATOM   1725 C CG  . ASN A 1 376 ? 140.146 133.185 160.928 1.00 45.13 ? 376 ASN A CG  1 
ATOM   1726 O OD1 . ASN A 1 376 ? 139.957 132.283 161.743 1.00 43.09 ? 376 ASN A OD1 1 
ATOM   1727 N ND2 . ASN A 1 376 ? 139.548 134.366 161.017 1.00 36.88 ? 376 ASN A ND2 1 
ATOM   1728 N N   . PRO A 1 377 ? 143.309 131.646 157.846 1.00 40.58 ? 377 PRO A N   1 
ATOM   1729 C CA  . PRO A 1 377 ? 143.829 131.204 156.546 1.00 37.91 ? 377 PRO A CA  1 
ATOM   1730 C C   . PRO A 1 377 ? 143.786 129.701 156.332 1.00 39.48 ? 377 PRO A C   1 
ATOM   1731 O O   . PRO A 1 377 ? 143.536 129.245 155.211 1.00 42.52 ? 377 PRO A O   1 
ATOM   1732 C CB  . PRO A 1 377 ? 145.283 131.704 156.599 1.00 43.74 ? 377 PRO A CB  1 
ATOM   1733 C CG  . PRO A 1 377 ? 145.321 132.647 157.831 1.00 44.19 ? 377 PRO A CG  1 
ATOM   1734 C CD  . PRO A 1 377 ? 143.910 132.959 158.090 1.00 45.30 ? 377 PRO A CD  1 
ATOM   1735 N N   . LEU A 1 378 ? 144.037 128.918 157.377 1.00 37.48 ? 378 LEU A N   1 
ATOM   1736 C CA  . LEU A 1 378 ? 144.228 127.480 157.235 1.00 34.43 ? 378 LEU A CA  1 
ATOM   1737 C C   . LEU A 1 378 ? 142.914 126.711 157.191 1.00 32.64 ? 378 LEU A C   1 
ATOM   1738 O O   . LEU A 1 378 ? 142.680 125.940 156.256 1.00 39.65 ? 378 LEU A O   1 
ATOM   1739 C CB  . LEU A 1 378 ? 145.086 126.960 158.390 1.00 33.37 ? 378 LEU A CB  1 
ATOM   1740 C CG  . LEU A 1 378 ? 146.498 127.536 158.502 1.00 37.95 ? 378 LEU A CG  1 
ATOM   1741 C CD1 . LEU A 1 378 ? 147.125 127.099 159.806 1.00 36.74 ? 378 LEU A CD1 1 
ATOM   1742 C CD2 . LEU A 1 378 ? 147.362 127.110 157.337 1.00 39.72 ? 378 LEU A CD2 1 
ATOM   1743 N N   . VAL A 1 379 ? 142.046 126.900 158.186 1.00 28.86 ? 379 VAL A N   1 
ATOM   1744 C CA  . VAL A 1 379 ? 140.830 126.100 158.261 1.00 26.68 ? 379 VAL A CA  1 
ATOM   1745 C C   . VAL A 1 379 ? 139.846 126.444 157.151 1.00 34.33 ? 379 VAL A C   1 
ATOM   1746 O O   . VAL A 1 379 ? 139.010 125.604 156.796 1.00 42.67 ? 379 VAL A O   1 
ATOM   1747 C CB  . VAL A 1 379 ? 140.157 126.245 159.642 1.00 36.02 ? 379 VAL A CB  1 
ATOM   1748 C CG1 . VAL A 1 379 ? 141.043 125.654 160.722 1.00 39.07 ? 379 VAL A CG1 1 
ATOM   1749 C CG2 . VAL A 1 379 ? 139.807 127.702 159.964 1.00 41.57 ? 379 VAL A CG2 1 
ATOM   1750 N N   . TYR A 1 380 ? 139.907 127.657 156.598 1.00 31.84 ? 380 TYR A N   1 
ATOM   1751 C CA  . TYR A 1 380 ? 139.000 128.051 155.526 1.00 37.96 ? 380 TYR A CA  1 
ATOM   1752 C C   . TYR A 1 380 ? 139.525 127.729 154.133 1.00 37.13 ? 380 TYR A C   1 
ATOM   1753 O O   . TYR A 1 380 ? 138.748 127.789 153.175 1.00 40.44 ? 380 TYR A O   1 
ATOM   1754 C CB  . TYR A 1 380 ? 138.707 129.551 155.602 1.00 37.20 ? 380 TYR A CB  1 
ATOM   1755 C CG  . TYR A 1 380 ? 137.595 129.896 156.559 1.00 41.51 ? 380 TYR A CG  1 
ATOM   1756 C CD1 . TYR A 1 380 ? 137.856 130.146 157.897 1.00 30.19 ? 380 TYR A CD1 1 
ATOM   1757 C CD2 . TYR A 1 380 ? 136.278 129.950 156.128 1.00 35.50 ? 380 TYR A CD2 1 
ATOM   1758 C CE1 . TYR A 1 380 ? 136.840 130.452 158.774 1.00 28.40 ? 380 TYR A CE1 1 
ATOM   1759 C CE2 . TYR A 1 380 ? 135.257 130.254 156.996 1.00 35.65 ? 380 TYR A CE2 1 
ATOM   1760 C CZ  . TYR A 1 380 ? 135.541 130.501 158.318 1.00 41.55 ? 380 TYR A CZ  1 
ATOM   1761 O OH  . TYR A 1 380 ? 134.518 130.806 159.186 1.00 44.92 ? 380 TYR A OH  1 
ATOM   1762 N N   . THR A 1 381 ? 140.808 127.397 153.995 1.00 40.15 ? 381 THR A N   1 
ATOM   1763 C CA  . THR A 1 381 ? 141.432 127.134 152.702 1.00 33.70 ? 381 THR A CA  1 
ATOM   1764 C C   . THR A 1 381 ? 142.036 125.747 152.588 1.00 37.55 ? 381 THR A C   1 
ATOM   1765 O O   . THR A 1 381 ? 141.826 125.072 151.580 1.00 45.42 ? 381 THR A O   1 
ATOM   1766 C CB  . THR A 1 381 ? 142.539 128.163 152.427 1.00 39.19 ? 381 THR A CB  1 
ATOM   1767 O OG1 . THR A 1 381 ? 143.621 127.960 153.343 1.00 38.82 ? 381 THR A OG1 1 
ATOM   1768 C CG2 . THR A 1 381 ? 142.019 129.585 152.553 1.00 42.72 ? 381 THR A CG2 1 
ATOM   1769 N N   . LEU A 1 382 ? 142.766 125.291 153.602 1.00 40.51 ? 382 LEU A N   1 
ATOM   1770 C CA  . LEU A 1 382 ? 143.625 124.121 153.461 1.00 43.36 ? 382 LEU A CA  1 
ATOM   1771 C C   . LEU A 1 382 ? 142.853 122.818 153.306 1.00 45.83 ? 382 LEU A C   1 
ATOM   1772 O O   . LEU A 1 382 ? 143.468 121.797 152.983 1.00 51.80 ? 382 LEU A O   1 
ATOM   1773 C CB  . LEU A 1 382 ? 144.571 124.011 154.661 1.00 45.63 ? 382 LEU A CB  1 
ATOM   1774 C CG  . LEU A 1 382 ? 146.004 123.555 154.380 1.00 45.14 ? 382 LEU A CG  1 
ATOM   1775 C CD1 . LEU A 1 382 ? 146.759 124.563 153.526 1.00 40.47 ? 382 LEU A CD1 1 
ATOM   1776 C CD2 . LEU A 1 382 ? 146.738 123.308 155.684 1.00 44.56 ? 382 LEU A CD2 1 
ATOM   1777 N N   . PHE A 1 383 ? 141.540 122.812 153.529 1.00 38.01 ? 383 PHE A N   1 
ATOM   1778 C CA  . PHE A 1 383 ? 140.749 121.624 153.242 1.00 39.41 ? 383 PHE A CA  1 
ATOM   1779 C C   . PHE A 1 383 ? 140.644 121.333 151.750 1.00 40.82 ? 383 PHE A C   1 
ATOM   1780 O O   . PHE A 1 383 ? 140.277 120.213 151.382 1.00 39.19 ? 383 PHE A O   1 
ATOM   1781 C CB  . PHE A 1 383 ? 139.349 121.767 153.840 1.00 36.34 ? 383 PHE A CB  1 
ATOM   1782 C CG  . PHE A 1 383 ? 139.302 121.547 155.325 1.00 34.05 ? 383 PHE A CG  1 
ATOM   1783 C CD1 . PHE A 1 383 ? 139.602 122.574 156.199 1.00 40.62 ? 383 PHE A CD1 1 
ATOM   1784 C CD2 . PHE A 1 383 ? 138.968 120.310 155.846 1.00 34.88 ? 383 PHE A CD2 1 
ATOM   1785 C CE1 . PHE A 1 383 ? 139.564 122.374 157.564 1.00 41.21 ? 383 PHE A CE1 1 
ATOM   1786 C CE2 . PHE A 1 383 ? 138.932 120.106 157.211 1.00 36.50 ? 383 PHE A CE2 1 
ATOM   1787 C CZ  . PHE A 1 383 ? 139.228 121.140 158.069 1.00 35.30 ? 383 PHE A CZ  1 
ATOM   1788 N N   . ASN A 1 384 ? 141.033 122.300 150.914 1.00 44.99 ? 384 ASN A N   1 
ATOM   1789 C CA  . ASN A 1 384 ? 140.956 122.130 149.436 1.00 46.63 ? 384 ASN A CA  1 
ATOM   1790 C C   . ASN A 1 384 ? 142.242 121.463 148.930 1.00 47.53 ? 384 ASN A C   1 
ATOM   1791 O O   . ASN A 1 384 ? 143.339 121.928 149.315 1.00 46.71 ? 384 ASN A O   1 
ATOM   1792 C CB  . ASN A 1 384 ? 140.664 123.473 148.773 1.00 42.90 ? 384 ASN A CB  1 
ATOM   1793 C CG  . ASN A 1 384 ? 140.877 123.470 147.279 1.00 49.24 ? 384 ASN A CG  1 
ATOM   1794 O OD1 . ASN A 1 384 ? 140.610 122.470 146.604 1.00 52.49 ? 384 ASN A OD1 1 
ATOM   1795 N ND2 . ASN A 1 384 ? 141.335 124.592 146.743 1.00 46.07 ? 384 ASN A ND2 1 
ATOM   1796 N N   . LYS A 1 385 ? 142.115 120.423 148.094 1.00 54.34 ? 385 LYS A N   1 
ATOM   1797 C CA  . LYS A 1 385 ? 143.296 119.770 147.544 1.00 54.96 ? 385 LYS A CA  1 
ATOM   1798 C C   . LYS A 1 385 ? 144.190 120.766 146.821 1.00 52.18 ? 385 LYS A C   1 
ATOM   1799 O O   . LYS A 1 385 ? 145.419 120.663 146.897 1.00 45.37 ? 385 LYS A O   1 
ATOM   1800 C CB  . LYS A 1 385 ? 142.881 118.646 146.594 1.00 56.53 ? 385 LYS A CB  1 
ATOM   1801 C CG  . LYS A 1 385 ? 142.524 117.332 147.288 1.00 54.29 ? 385 LYS A CG  1 
ATOM   1802 C CD  . LYS A 1 385 ? 143.416 116.178 146.843 1.00 55.91 ? 385 LYS A CD  1 
ATOM   1803 C CE  . LYS A 1 385 ? 143.386 115.038 147.845 1.00 57.76 ? 385 LYS A CE  1 
ATOM   1804 N NZ  . LYS A 1 385 ? 144.487 115.151 148.840 1.00 56.95 ? 385 LYS A NZ  1 
ATOM   1805 N N   . THR A 1 386 ? 143.592 121.730 146.118 1.00 60.49 ? 386 THR A N   1 
ATOM   1806 C CA  . THR A 1 386 ? 144.375 122.696 145.353 1.00 62.52 ? 386 THR A CA  1 
ATOM   1807 C C   . THR A 1 386 ? 145.231 123.568 146.262 1.00 58.13 ? 386 THR A C   1 
ATOM   1808 O O   . THR A 1 386 ? 146.396 123.842 145.950 1.00 58.39 ? 386 THR A O   1 
ATOM   1809 C CB  . THR A 1 386 ? 143.444 123.565 144.508 1.00 58.11 ? 386 THR A CB  1 
ATOM   1810 O OG1 . THR A 1 386 ? 142.397 122.757 143.956 1.00 57.77 ? 386 THR A OG1 1 
ATOM   1811 C CG2 . THR A 1 386 ? 144.213 124.233 143.381 1.00 53.36 ? 386 THR A CG2 1 
ATOM   1812 N N   . TYR A 1 387 ? 144.671 124.023 147.386 1.00 47.10 ? 387 TYR A N   1 
ATOM   1813 C CA  . TYR A 1 387 ? 145.423 124.894 148.283 1.00 44.42 ? 387 TYR A CA  1 
ATOM   1814 C C   . TYR A 1 387 ? 146.603 124.164 148.906 1.00 53.20 ? 387 TYR A C   1 
ATOM   1815 O O   . TYR A 1 387 ? 147.671 124.758 149.085 1.00 52.54 ? 387 TYR A O   1 
ATOM   1816 C CB  . TYR A 1 387 ? 144.514 125.434 149.383 1.00 46.85 ? 387 TYR A CB  1 
ATOM   1817 C CG  . TYR A 1 387 ? 143.894 126.780 149.088 1.00 43.66 ? 387 TYR A CG  1 
ATOM   1818 C CD1 . TYR A 1 387 ? 144.663 127.928 149.003 1.00 41.36 ? 387 TYR A CD1 1 
ATOM   1819 C CD2 . TYR A 1 387 ? 142.526 126.899 148.910 1.00 52.37 ? 387 TYR A CD2 1 
ATOM   1820 C CE1 . TYR A 1 387 ? 144.083 129.148 148.739 1.00 45.85 ? 387 TYR A CE1 1 
ATOM   1821 C CE2 . TYR A 1 387 ? 141.943 128.111 148.655 1.00 41.96 ? 387 TYR A CE2 1 
ATOM   1822 C CZ  . TYR A 1 387 ? 142.722 129.231 148.568 1.00 40.01 ? 387 TYR A CZ  1 
ATOM   1823 O OH  . TYR A 1 387 ? 142.127 130.440 148.306 1.00 53.20 ? 387 TYR A OH  1 
ATOM   1824 N N   . ARG A 1 388 ? 146.427 122.887 149.255 1.00 59.68 ? 388 ARG A N   1 
ATOM   1825 C CA  . ARG A 1 388 ? 147.528 122.111 149.815 1.00 54.64 ? 388 ARG A CA  1 
ATOM   1826 C C   . ARG A 1 388 ? 148.683 122.011 148.827 1.00 53.73 ? 388 ARG A C   1 
ATOM   1827 O O   . ARG A 1 388 ? 149.849 122.167 149.206 1.00 47.19 ? 388 ARG A O   1 
ATOM   1828 C CB  . ARG A 1 388 ? 147.036 120.717 150.206 1.00 50.47 ? 388 ARG A CB  1 
ATOM   1829 C CG  . ARG A 1 388 ? 146.110 120.705 151.417 1.00 48.64 ? 388 ARG A CG  1 
ATOM   1830 C CD  . ARG A 1 388 ? 146.072 119.355 152.131 1.00 51.01 ? 388 ARG A CD  1 
ATOM   1831 N NE  . ARG A 1 388 ? 145.158 118.410 151.498 1.00 54.50 ? 388 ARG A NE  1 
ATOM   1832 C CZ  . ARG A 1 388 ? 143.835 118.439 151.606 1.00 51.21 ? 388 ARG A CZ  1 
ATOM   1833 N NH1 . ARG A 1 388 ? 143.212 119.387 152.287 1.00 50.03 ? 388 ARG A NH1 1 
ATOM   1834 N NH2 . ARG A 1 388 ? 143.116 117.490 151.015 1.00 51.36 ? 388 ARG A NH2 1 
ATOM   1835 N N   . SER A 1 389 ? 148.375 121.755 147.555 1.00 58.83 ? 389 SER A N   1 
ATOM   1836 C CA  . SER A 1 389 ? 149.408 121.746 146.527 1.00 57.28 ? 389 SER A CA  1 
ATOM   1837 C C   . SER A 1 389 ? 150.027 123.127 146.357 1.00 57.57 ? 389 SER A C   1 
ATOM   1838 O O   . SER A 1 389 ? 151.248 123.253 146.209 1.00 58.35 ? 389 SER A O   1 
ATOM   1839 C CB  . SER A 1 389 ? 148.819 121.260 145.204 1.00 55.75 ? 389 SER A CB  1 
ATOM   1840 O OG  . SER A 1 389 ? 148.210 122.327 144.499 1.00 56.60 ? 389 SER A OG  1 
ATOM   1841 N N   . ALA A 1 390 ? 149.198 124.175 146.378 1.00 55.85 ? 390 ALA A N   1 
ATOM   1842 C CA  . ALA A 1 390 ? 149.702 125.530 146.180 1.00 58.23 ? 390 ALA A CA  1 
ATOM   1843 C C   . ALA A 1 390 ? 150.672 125.939 147.282 1.00 61.56 ? 390 ALA A C   1 
ATOM   1844 O O   . ALA A 1 390 ? 151.689 126.584 147.001 1.00 64.24 ? 390 ALA A O   1 
ATOM   1845 C CB  . ALA A 1 390 ? 148.537 126.516 146.108 1.00 53.03 ? 390 ALA A CB  1 
ATOM   1846 N N   . PHE A 1 391 ? 150.377 125.586 148.533 1.00 54.23 ? 391 PHE A N   1 
ATOM   1847 C CA  . PHE A 1 391 ? 151.281 125.922 149.628 1.00 51.55 ? 391 PHE A CA  1 
ATOM   1848 C C   . PHE A 1 391 ? 152.620 125.213 149.474 1.00 56.20 ? 391 PHE A C   1 
ATOM   1849 O O   . PHE A 1 391 ? 153.674 125.807 149.727 1.00 55.43 ? 391 PHE A O   1 
ATOM   1850 C CB  . PHE A 1 391 ? 150.639 125.560 150.968 1.00 50.80 ? 391 PHE A CB  1 
ATOM   1851 C CG  . PHE A 1 391 ? 149.707 126.612 151.514 1.00 51.08 ? 391 PHE A CG  1 
ATOM   1852 C CD1 . PHE A 1 391 ? 148.953 127.416 150.675 1.00 51.45 ? 391 PHE A CD1 1 
ATOM   1853 C CD2 . PHE A 1 391 ? 149.577 126.783 152.879 1.00 52.62 ? 391 PHE A CD2 1 
ATOM   1854 C CE1 . PHE A 1 391 ? 148.102 128.371 151.189 1.00 48.91 ? 391 PHE A CE1 1 
ATOM   1855 C CE2 . PHE A 1 391 ? 148.727 127.735 153.396 1.00 50.14 ? 391 PHE A CE2 1 
ATOM   1856 C CZ  . PHE A 1 391 ? 147.989 128.528 152.551 1.00 49.76 ? 391 PHE A CZ  1 
ATOM   1857 N N   . SER A 1 392 ? 152.600 123.943 149.062 1.00 63.09 ? 392 SER A N   1 
ATOM   1858 C CA  . SER A 1 392 ? 153.845 123.194 148.919 1.00 65.67 ? 392 SER A CA  1 
ATOM   1859 C C   . SER A 1 392 ? 154.737 123.805 147.846 1.00 67.15 ? 392 SER A C   1 
ATOM   1860 O O   . SER A 1 392 ? 155.953 123.927 148.034 1.00 64.97 ? 392 SER A O   1 
ATOM   1861 C CB  . SER A 1 392 ? 153.542 121.732 148.593 1.00 61.26 ? 392 SER A CB  1 
ATOM   1862 N N   . ARG A 1 393 ? 154.153 124.198 146.719 1.00 67.03 ? 393 ARG A N   1 
ATOM   1863 C CA  . ARG A 1 393 ? 154.913 124.808 145.635 1.00 63.58 ? 393 ARG A CA  1 
ATOM   1864 C C   . ARG A 1 393 ? 155.244 126.259 145.963 1.00 62.95 ? 393 ARG A C   1 
ATOM   1865 O O   . ARG A 1 393 ? 155.524 126.598 147.113 1.00 57.24 ? 393 ARG A O   1 
ATOM   1866 C CB  . ARG A 1 393 ? 154.134 124.729 144.321 1.00 57.06 ? 393 ARG A CB  1 
ATOM   1867 N N   . THR B 2 4   ? 143.527 163.629 121.622 1.00 55.56 ? 4   THR B N   1 
ATOM   1868 C CA  . THR B 2 4   ? 144.263 162.408 121.314 1.00 61.01 ? 4   THR B CA  1 
ATOM   1869 C C   . THR B 2 4   ? 143.345 161.315 120.763 1.00 58.42 ? 4   THR B C   1 
ATOM   1870 O O   . THR B 2 4   ? 143.814 160.393 120.093 1.00 60.19 ? 4   THR B O   1 
ATOM   1871 C CB  . THR B 2 4   ? 145.003 161.876 122.553 1.00 64.98 ? 4   THR B CB  1 
ATOM   1872 O OG1 . THR B 2 4   ? 144.059 161.336 123.486 1.00 63.99 ? 4   THR B OG1 1 
ATOM   1873 C CG2 . THR B 2 4   ? 145.794 162.993 123.216 1.00 61.89 ? 4   THR B CG2 1 
ATOM   1874 N N   . VAL B 2 5   ? 142.050 161.410 121.064 1.00 49.51 ? 5   VAL B N   1 
ATOM   1875 C CA  . VAL B 2 5   ? 141.014 160.601 120.428 1.00 48.35 ? 5   VAL B CA  1 
ATOM   1876 C C   . VAL B 2 5   ? 140.059 161.552 119.723 1.00 49.32 ? 5   VAL B C   1 
ATOM   1877 O O   . VAL B 2 5   ? 139.519 162.475 120.344 1.00 48.12 ? 5   VAL B O   1 
ATOM   1878 C CB  . VAL B 2 5   ? 140.264 159.701 121.433 1.00 44.67 ? 5   VAL B CB  1 
ATOM   1879 C CG1 . VAL B 2 5   ? 141.105 158.485 121.774 1.00 44.31 ? 5   VAL B CG1 1 
ATOM   1880 C CG2 . VAL B 2 5   ? 139.866 160.453 122.710 1.00 43.31 ? 5   VAL B CG2 1 
ATOM   1881 N N   . SER B 2 6   ? 139.864 161.338 118.426 1.00 38.12 ? 6   SER B N   1 
ATOM   1882 C CA  . SER B 2 6   ? 138.985 162.200 117.658 1.00 31.96 ? 6   SER B CA  1 
ATOM   1883 C C   . SER B 2 6   ? 137.545 162.033 118.128 1.00 33.75 ? 6   SER B C   1 
ATOM   1884 O O   . SER B 2 6   ? 137.214 161.121 118.888 1.00 38.66 ? 6   SER B O   1 
ATOM   1885 C CB  . SER B 2 6   ? 139.101 161.886 116.167 1.00 33.65 ? 6   SER B CB  1 
ATOM   1886 O OG  . SER B 2 6   ? 139.104 160.488 115.946 1.00 36.63 ? 6   SER B OG  1 
ATOM   1887 N N   . ALA B 2 7   ? 136.685 162.951 117.682 1.00 32.47 ? 7   ALA B N   1 
ATOM   1888 C CA  . ALA B 2 7   ? 135.271 162.872 118.029 1.00 29.29 ? 7   ALA B CA  1 
ATOM   1889 C C   . ALA B 2 7   ? 134.652 161.584 117.505 1.00 26.76 ? 7   ALA B C   1 
ATOM   1890 O O   . ALA B 2 7   ? 133.846 160.941 118.191 1.00 24.83 ? 7   ALA B O   1 
ATOM   1891 C CB  . ALA B 2 7   ? 134.531 164.086 117.473 1.00 21.21 ? 7   ALA B CB  1 
ATOM   1892 N N   . GLU B 2 8   ? 135.049 161.198 116.290 1.00 20.05 ? 8   GLU B N   1 
ATOM   1893 C CA  . GLU B 2 8   ? 134.501 159.962 115.674 1.00 20.41 ? 8   GLU B CA  1 
ATOM   1894 C C   . GLU B 2 8   ? 134.974 158.741 116.481 1.00 26.63 ? 8   GLU B C   1 
ATOM   1895 O O   . GLU B 2 8   ? 134.150 157.828 116.707 1.00 39.78 ? 8   GLU B O   1 
ATOM   1896 C CB  . GLU B 2 8   ? 134.923 159.892 114.207 1.00 18.27 ? 8   GLU B CB  1 
ATOM   1897 C CG  . GLU B 2 8   ? 134.672 161.200 113.463 1.00 13.51 ? 8   GLU B CG  1 
ATOM   1898 C CD  . GLU B 2 8   ? 134.140 161.021 112.055 1.00 24.73 ? 8   GLU B CD  1 
ATOM   1899 O OE1 . GLU B 2 8   ? 134.830 160.381 111.234 1.00 40.84 ? 8   GLU B OE1 1 
ATOM   1900 O OE2 . GLU B 2 8   ? 133.030 161.524 111.780 1.00 25.96 ? 8   GLU B OE2 1 
ATOM   1901 N N   . ASP B 2 9   ? 136.243 158.732 116.904 1.00 13.77 ? 9   ASP B N   1 
ATOM   1902 C CA  . ASP B 2 9   ? 136.744 157.610 117.692 1.00 21.57 ? 9   ASP B CA  1 
ATOM   1903 C C   . ASP B 2 9   ? 136.078 157.562 119.062 1.00 25.17 ? 9   ASP B C   1 
ATOM   1904 O O   . ASP B 2 9   ? 135.834 156.479 119.606 1.00 35.22 ? 9   ASP B O   1 
ATOM   1905 C CB  . ASP B 2 9   ? 138.262 157.698 117.833 1.00 32.06 ? 9   ASP B CB  1 
ATOM   1906 C CG  . ASP B 2 9   ? 138.929 156.341 117.765 1.00 42.08 ? 9   ASP B CG  1 
ATOM   1907 O OD1 . ASP B 2 9   ? 138.510 155.434 118.515 1.00 29.91 ? 9   ASP B OD1 1 
ATOM   1908 O OD2 . ASP B 2 9   ? 139.868 156.181 116.957 1.00 39.48 ? 9   ASP B OD2 1 
ATOM   1909 N N   . LYS B 2 10  ? 135.771 158.729 119.632 1.00 17.78 ? 10  LYS B N   1 
ATOM   1910 C CA  . LYS B 2 10  ? 135.021 158.771 120.884 1.00 20.24 ? 10  LYS B CA  1 
ATOM   1911 C C   . LYS B 2 10  ? 133.629 158.177 120.711 1.00 24.67 ? 10  LYS B C   1 
ATOM   1912 O O   . LYS B 2 10  ? 133.154 157.414 121.563 1.00 25.36 ? 10  LYS B O   1 
ATOM   1913 C CB  . LYS B 2 10  ? 134.922 160.213 121.379 1.00 22.34 ? 10  LYS B CB  1 
ATOM   1914 C CG  . LYS B 2 10  ? 136.113 160.663 122.235 1.00 27.65 ? 10  LYS B CG  1 
ATOM   1915 C CD  . LYS B 2 10  ? 135.945 162.030 122.925 1.00 34.97 ? 10  LYS B CD  1 
ATOM   1916 C CE  . LYS B 2 10  ? 134.702 162.162 123.802 1.00 34.46 ? 10  LYS B CE  1 
ATOM   1917 N NZ  . LYS B 2 10  ? 134.662 161.126 124.868 1.00 32.75 ? 10  LYS B NZ  1 
ATOM   1918 N N   . ALA B 2 11  ? 132.954 158.525 119.614 1.00 17.72 ? 11  ALA B N   1 
ATOM   1919 C CA  . ALA B 2 11  ? 131.638 157.955 119.344 1.00 13.50 ? 11  ALA B CA  1 
ATOM   1920 C C   . ALA B 2 11  ? 131.724 156.451 119.117 1.00 17.71 ? 11  ALA B C   1 
ATOM   1921 O O   . ALA B 2 11  ? 130.828 155.700 119.521 1.00 28.83 ? 11  ALA B O   1 
ATOM   1922 C CB  . ALA B 2 11  ? 131.009 158.646 118.140 1.00 15.43 ? 11  ALA B CB  1 
ATOM   1923 N N   . ALA B 2 12  ? 132.796 155.993 118.467 1.00 7.17  ? 12  ALA B N   1 
ATOM   1924 C CA  . ALA B 2 12  ? 133.011 154.559 118.308 1.00 6.23  ? 12  ALA B CA  1 
ATOM   1925 C C   . ALA B 2 12  ? 133.186 153.878 119.659 1.00 16.74 ? 12  ALA B C   1 
ATOM   1926 O O   . ALA B 2 12  ? 132.686 152.768 119.874 1.00 37.03 ? 12  ALA B O   1 
ATOM   1927 C CB  . ALA B 2 12  ? 134.229 154.309 117.424 1.00 12.10 ? 12  ALA B CB  1 
ATOM   1928 N N   . ALA B 2 13  ? 133.903 154.527 120.579 1.00 12.06 ? 13  ALA B N   1 
ATOM   1929 C CA  . ALA B 2 13  ? 134.066 153.972 121.920 1.00 13.73 ? 13  ALA B CA  1 
ATOM   1930 C C   . ALA B 2 13  ? 132.731 153.887 122.651 1.00 13.84 ? 13  ALA B C   1 
ATOM   1931 O O   . ALA B 2 13  ? 132.459 152.903 123.352 1.00 17.36 ? 13  ALA B O   1 
ATOM   1932 C CB  . ALA B 2 13  ? 135.061 154.815 122.713 1.00 16.86 ? 13  ALA B CB  1 
ATOM   1933 N N   . GLU B 2 14  ? 131.887 154.913 122.508 1.00 13.67 ? 14  GLU B N   1 
ATOM   1934 C CA  . GLU B 2 14  ? 130.552 154.860 123.106 1.00 13.08 ? 14  GLU B CA  1 
ATOM   1935 C C   . GLU B 2 14  ? 129.727 153.719 122.521 1.00 19.39 ? 14  GLU B C   1 
ATOM   1936 O O   . GLU B 2 14  ? 129.003 153.024 123.249 1.00 26.29 ? 14  GLU B O   1 
ATOM   1937 C CB  . GLU B 2 14  ? 129.823 156.185 122.900 1.00 10.39 ? 14  GLU B CB  1 
ATOM   1938 C CG  . GLU B 2 14  ? 130.434 157.360 123.639 1.00 26.22 ? 14  GLU B CG  1 
ATOM   1939 C CD  . GLU B 2 14  ? 129.524 158.578 123.673 1.00 35.64 ? 14  GLU B CD  1 
ATOM   1940 O OE1 . GLU B 2 14  ? 128.358 158.477 123.235 1.00 27.85 ? 14  GLU B OE1 1 
ATOM   1941 O OE2 . GLU B 2 14  ? 129.980 159.641 124.144 1.00 27.54 ? 14  GLU B OE2 1 
ATOM   1942 N N   . ARG B 2 15  ? 129.814 153.524 121.203 1.00 22.68 ? 15  ARG B N   1 
ATOM   1943 C CA  . ARG B 2 15  ? 129.124 152.411 120.560 1.00 21.31 ? 15  ARG B CA  1 
ATOM   1944 C C   . ARG B 2 15  ? 129.599 151.076 121.119 1.00 26.93 ? 15  ARG B C   1 
ATOM   1945 O O   . ARG B 2 15  ? 128.786 150.186 121.406 1.00 32.44 ? 15  ARG B O   1 
ATOM   1946 C CB  . ARG B 2 15  ? 129.356 152.477 119.051 1.00 17.03 ? 15  ARG B CB  1 
ATOM   1947 C CG  . ARG B 2 15  ? 128.518 151.514 118.213 1.00 28.48 ? 15  ARG B CG  1 
ATOM   1948 C CD  . ARG B 2 15  ? 129.062 151.391 116.801 1.00 23.91 ? 15  ARG B CD  1 
ATOM   1949 N NE  . ARG B 2 15  ? 128.537 150.223 116.105 1.00 10.77 ? 15  ARG B NE  1 
ATOM   1950 C CZ  . ARG B 2 15  ? 127.304 150.104 115.631 1.00 14.94 ? 15  ARG B CZ  1 
ATOM   1951 N NH1 . ARG B 2 15  ? 126.406 151.067 115.767 1.00 19.65 ? 15  ARG B NH1 1 
ATOM   1952 N NH2 . ARG B 2 15  ? 126.961 148.987 115.000 1.00 23.11 ? 15  ARG B NH2 1 
ATOM   1953 N N   . SER B 2 16  ? 130.914 150.921 121.278 1.00 18.37 ? 16  SER B N   1 
ATOM   1954 C CA  . SER B 2 16  ? 131.456 149.679 121.818 1.00 13.53 ? 16  SER B CA  1 
ATOM   1955 C C   . SER B 2 16  ? 130.988 149.444 123.246 1.00 26.82 ? 16  SER B C   1 
ATOM   1956 O O   . SER B 2 16  ? 130.706 148.305 123.634 1.00 27.13 ? 16  SER B O   1 
ATOM   1957 C CB  . SER B 2 16  ? 132.979 149.702 121.762 1.00 17.27 ? 16  SER B CB  1 
ATOM   1958 O OG  . SER B 2 16  ? 133.512 148.575 122.429 1.00 35.31 ? 16  SER B OG  1 
ATOM   1959 N N   . LYS B 2 17  ? 130.910 150.506 124.050 1.00 34.68 ? 17  LYS B N   1 
ATOM   1960 C CA  . LYS B 2 17  ? 130.454 150.349 125.429 1.00 23.71 ? 17  LYS B CA  1 
ATOM   1961 C C   . LYS B 2 17  ? 128.981 149.954 125.487 1.00 21.61 ? 17  LYS B C   1 
ATOM   1962 O O   . LYS B 2 17  ? 128.585 149.127 126.319 1.00 33.02 ? 17  LYS B O   1 
ATOM   1963 C CB  . LYS B 2 17  ? 130.712 151.634 126.210 1.00 23.01 ? 17  LYS B CB  1 
ATOM   1964 C CG  . LYS B 2 17  ? 132.189 151.837 126.538 1.00 26.61 ? 17  LYS B CG  1 
ATOM   1965 C CD  . LYS B 2 17  ? 132.570 153.302 126.697 1.00 33.35 ? 17  LYS B CD  1 
ATOM   1966 C CE  . LYS B 2 17  ? 134.083 153.470 126.715 1.00 33.92 ? 17  LYS B CE  1 
ATOM   1967 N NZ  . LYS B 2 17  ? 134.491 154.888 126.897 1.00 32.32 ? 17  LYS B NZ  1 
ATOM   1968 N N   . MET B 2 18  ? 128.154 150.526 124.608 1.00 19.70 ? 18  MET B N   1 
ATOM   1969 C CA  . MET B 2 18  ? 126.754 150.106 124.542 1.00 18.15 ? 18  MET B CA  1 
ATOM   1970 C C   . MET B 2 18  ? 126.639 148.643 124.128 1.00 21.43 ? 18  MET B C   1 
ATOM   1971 O O   . MET B 2 18  ? 125.804 147.895 124.662 1.00 37.05 ? 18  MET B O   1 
ATOM   1972 C CB  . MET B 2 18  ? 125.984 150.993 123.566 1.00 24.94 ? 18  MET B CB  1 
ATOM   1973 C CG  . MET B 2 18  ? 125.692 152.403 124.092 1.00 31.04 ? 18  MET B CG  1 
ATOM   1974 S SD  . MET B 2 18  ? 124.282 153.277 123.363 1.00 47.24 ? 18  MET B SD  1 
ATOM   1975 C CE  . MET B 2 18  ? 122.920 152.127 123.560 1.00 32.46 ? 18  MET B CE  1 
ATOM   1976 N N   . ILE B 2 19  ? 127.471 148.217 123.173 1.00 29.79 ? 19  ILE B N   1 
ATOM   1977 C CA  . ILE B 2 19  ? 127.470 146.816 122.762 1.00 35.82 ? 19  ILE B CA  1 
ATOM   1978 C C   . ILE B 2 19  ? 127.867 145.925 123.933 1.00 29.58 ? 19  ILE B C   1 
ATOM   1979 O O   . ILE B 2 19  ? 127.265 144.870 124.154 1.00 41.90 ? 19  ILE B O   1 
ATOM   1980 C CB  . ILE B 2 19  ? 128.394 146.608 121.545 1.00 33.17 ? 19  ILE B CB  1 
ATOM   1981 C CG1 . ILE B 2 19  ? 127.796 147.275 120.298 1.00 23.77 ? 19  ILE B CG1 1 
ATOM   1982 C CG2 . ILE B 2 19  ? 128.595 145.112 121.273 1.00 26.23 ? 19  ILE B CG2 1 
ATOM   1983 C CD1 . ILE B 2 19  ? 128.778 147.496 119.170 1.00 18.44 ? 19  ILE B CD1 1 
ATOM   1984 N N   . ASP B 2 20  ? 128.889 146.334 124.692 1.00 21.88 ? 20  ASP B N   1 
ATOM   1985 C CA  . ASP B 2 20  ? 129.311 145.577 125.870 1.00 30.41 ? 20  ASP B CA  1 
ATOM   1986 C C   . ASP B 2 20  ? 128.171 145.438 126.869 1.00 33.58 ? 20  ASP B C   1 
ATOM   1987 O O   . ASP B 2 20  ? 127.966 144.364 127.451 1.00 33.42 ? 20  ASP B O   1 
ATOM   1988 C CB  . ASP B 2 20  ? 130.498 146.276 126.543 1.00 35.24 ? 20  ASP B CB  1 
ATOM   1989 C CG  . ASP B 2 20  ? 131.850 145.817 126.018 1.00 39.52 ? 20  ASP B CG  1 
ATOM   1990 O OD1 . ASP B 2 20  ? 132.006 144.637 125.649 1.00 47.43 ? 20  ASP B OD1 1 
ATOM   1991 O OD2 . ASP B 2 20  ? 132.774 146.657 125.973 1.00 30.67 ? 20  ASP B OD2 1 
ATOM   1992 N N   . LYS B 2 21  ? 127.420 146.520 127.074 1.00 34.61 ? 21  LYS B N   1 
ATOM   1993 C CA  . LYS B 2 21  ? 126.282 146.489 127.988 1.00 34.50 ? 21  LYS B CA  1 
ATOM   1994 C C   . LYS B 2 21  ? 125.239 145.474 127.530 1.00 38.49 ? 21  LYS B C   1 
ATOM   1995 O O   . LYS B 2 21  ? 124.733 144.677 128.335 1.00 46.00 ? 21  LYS B O   1 
ATOM   1996 C CB  . LYS B 2 21  ? 125.700 147.904 128.083 1.00 33.91 ? 21  LYS B CB  1 
ATOM   1997 C CG  . LYS B 2 21  ? 124.356 148.093 128.821 1.00 41.05 ? 21  LYS B CG  1 
ATOM   1998 C CD  . LYS B 2 21  ? 123.758 149.519 128.694 1.00 40.44 ? 21  LYS B CD  1 
ATOM   1999 C CE  . LYS B 2 21  ? 124.777 150.665 128.612 1.00 40.17 ? 21  LYS B CE  1 
ATOM   2000 N NZ  . LYS B 2 21  ? 124.116 151.997 128.603 1.00 41.08 ? 21  LYS B NZ  1 
ATOM   2001 N N   . ASN B 2 22  ? 124.913 145.478 126.235 1.00 36.97 ? 22  ASN B N   1 
ATOM   2002 C CA  . ASN B 2 22  ? 123.892 144.554 125.743 1.00 36.44 ? 22  ASN B CA  1 
ATOM   2003 C C   . ASN B 2 22  ? 124.366 143.103 125.808 1.00 40.94 ? 22  ASN B C   1 
ATOM   2004 O O   . ASN B 2 22  ? 123.581 142.200 126.129 1.00 48.32 ? 22  ASN B O   1 
ATOM   2005 C CB  . ASN B 2 22  ? 123.484 144.932 124.322 1.00 43.58 ? 22  ASN B CB  1 
ATOM   2006 C CG  . ASN B 2 22  ? 122.568 146.138 124.290 1.00 46.13 ? 22  ASN B CG  1 
ATOM   2007 O OD1 . ASN B 2 22  ? 121.468 146.104 124.838 1.00 48.05 ? 22  ASN B OD1 1 
ATOM   2008 N ND2 . ASN B 2 22  ? 123.019 147.214 123.657 1.00 41.66 ? 22  ASN B ND2 1 
ATOM   2009 N N   . LEU B 2 23  ? 125.646 142.855 125.512 1.00 33.73 ? 23  LEU B N   1 
ATOM   2010 C CA  . LEU B 2 23  ? 126.183 141.503 125.654 1.00 30.06 ? 23  LEU B CA  1 
ATOM   2011 C C   . LEU B 2 23  ? 126.126 141.032 127.102 1.00 36.89 ? 23  LEU B C   1 
ATOM   2012 O O   . LEU B 2 23  ? 125.823 139.863 127.370 1.00 42.22 ? 23  LEU B O   1 
ATOM   2013 C CB  . LEU B 2 23  ? 127.621 141.436 125.134 1.00 32.89 ? 23  LEU B CB  1 
ATOM   2014 C CG  . LEU B 2 23  ? 127.885 141.774 123.663 1.00 32.23 ? 23  LEU B CG  1 
ATOM   2015 C CD1 . LEU B 2 23  ? 129.364 142.022 123.424 1.00 29.24 ? 23  LEU B CD1 1 
ATOM   2016 C CD2 . LEU B 2 23  ? 127.386 140.673 122.760 1.00 37.29 ? 23  LEU B CD2 1 
ATOM   2017 N N   . ARG B 2 24  ? 126.425 141.924 128.050 1.00 46.10 ? 24  ARG B N   1 
ATOM   2018 C CA  . ARG B 2 24  ? 126.346 141.549 129.459 1.00 43.61 ? 24  ARG B CA  1 
ATOM   2019 C C   . ARG B 2 24  ? 124.916 141.209 129.861 1.00 43.41 ? 24  ARG B C   1 
ATOM   2020 O O   . ARG B 2 24  ? 124.684 140.247 130.606 1.00 49.29 ? 24  ARG B O   1 
ATOM   2021 C CB  . ARG B 2 24  ? 126.891 142.674 130.334 1.00 44.58 ? 24  ARG B CB  1 
ATOM   2022 C CG  . ARG B 2 24  ? 128.403 142.649 130.490 1.00 45.79 ? 24  ARG B CG  1 
ATOM   2023 C CD  . ARG B 2 24  ? 128.894 143.610 131.565 1.00 49.00 ? 24  ARG B CD  1 
ATOM   2024 N NE  . ARG B 2 24  ? 128.202 144.900 131.520 1.00 52.01 ? 24  ARG B NE  1 
ATOM   2025 C CZ  . ARG B 2 24  ? 128.742 146.088 131.261 1.00 54.46 ? 24  ARG B CZ  1 
ATOM   2026 N NH1 . ARG B 2 24  ? 130.026 146.236 130.960 1.00 48.04 ? 24  ARG B NH1 1 
ATOM   2027 N NH2 . ARG B 2 24  ? 127.965 147.167 131.292 1.00 52.75 ? 24  ARG B NH2 1 
ATOM   2028 N N   . GLU B 2 25  ? 123.943 141.988 129.380 1.00 40.73 ? 25  GLU B N   1 
ATOM   2029 C CA  . GLU B 2 25  ? 122.545 141.681 129.679 1.00 45.87 ? 25  GLU B CA  1 
ATOM   2030 C C   . GLU B 2 25  ? 122.154 140.322 129.105 1.00 47.23 ? 25  GLU B C   1 
ATOM   2031 O O   . GLU B 2 25  ? 121.447 139.537 129.756 1.00 51.10 ? 25  GLU B O   1 
ATOM   2032 C CB  . GLU B 2 25  ? 121.648 142.810 129.148 1.00 47.71 ? 25  GLU B CB  1 
ATOM   2033 C CG  . GLU B 2 25  ? 120.112 142.611 129.212 1.00 49.99 ? 25  GLU B CG  1 
ATOM   2034 C CD  . GLU B 2 25  ? 119.524 141.769 128.082 1.00 54.50 ? 25  GLU B CD  1 
ATOM   2035 O OE1 . GLU B 2 25  ? 119.917 141.974 126.914 1.00 51.17 ? 25  GLU B OE1 1 
ATOM   2036 O OE2 . GLU B 2 25  ? 118.676 140.898 128.367 1.00 54.62 ? 25  GLU B OE2 1 
ATOM   2037 N N   . ASP B 2 26  ? 122.603 140.025 127.884 1.00 47.07 ? 26  ASP B N   1 
ATOM   2038 C CA  . ASP B 2 26  ? 122.274 138.741 127.273 1.00 47.56 ? 26  ASP B CA  1 
ATOM   2039 C C   . ASP B 2 26  ? 122.899 137.582 128.043 1.00 43.12 ? 26  ASP B C   1 
ATOM   2040 O O   . ASP B 2 26  ? 122.269 136.532 128.218 1.00 46.58 ? 26  ASP B O   1 
ATOM   2041 C CB  . ASP B 2 26  ? 122.725 138.729 125.817 1.00 48.00 ? 26  ASP B CB  1 
ATOM   2042 C CG  . ASP B 2 26  ? 121.894 139.650 124.946 1.00 51.90 ? 26  ASP B CG  1 
ATOM   2043 O OD1 . ASP B 2 26  ? 120.656 139.491 124.926 1.00 52.96 ? 26  ASP B OD1 1 
ATOM   2044 O OD2 . ASP B 2 26  ? 122.476 140.532 124.283 1.00 49.76 ? 26  ASP B OD2 1 
ATOM   2045 N N   . GLY B 2 27  ? 124.135 137.749 128.511 1.00 48.42 ? 27  GLY B N   1 
ATOM   2046 C CA  . GLY B 2 27  ? 124.740 136.713 129.336 1.00 51.16 ? 27  GLY B CA  1 
ATOM   2047 C C   . GLY B 2 27  ? 124.012 136.517 130.652 1.00 55.80 ? 27  GLY B C   1 
ATOM   2048 O O   . GLY B 2 27  ? 123.879 135.389 131.142 1.00 57.36 ? 27  GLY B O   1 
ATOM   2049 N N   . GLU B 2 28  ? 123.538 137.617 131.247 1.00 57.01 ? 28  GLU B N   1 
ATOM   2050 C CA  . GLU B 2 28  ? 122.737 137.516 132.463 1.00 55.15 ? 28  GLU B CA  1 
ATOM   2051 C C   . GLU B 2 28  ? 121.462 136.723 132.209 1.00 53.52 ? 28  GLU B C   1 
ATOM   2052 O O   . GLU B 2 28  ? 121.025 135.945 133.064 1.00 56.26 ? 28  GLU B O   1 
ATOM   2053 C CB  . GLU B 2 28  ? 122.404 138.911 132.989 1.00 52.47 ? 28  GLU B CB  1 
ATOM   2054 N N   . LYS B 2 29  ? 120.844 136.917 131.042 1.00 55.39 ? 29  LYS B N   1 
ATOM   2055 C CA  . LYS B 2 29  ? 119.716 136.066 130.668 1.00 52.70 ? 29  LYS B CA  1 
ATOM   2056 C C   . LYS B 2 29  ? 120.158 134.612 130.536 1.00 53.87 ? 29  LYS B C   1 
ATOM   2057 O O   . LYS B 2 29  ? 119.442 133.696 130.956 1.00 58.25 ? 29  LYS B O   1 
ATOM   2058 C CB  . LYS B 2 29  ? 119.094 136.551 129.355 1.00 53.14 ? 29  LYS B CB  1 
ATOM   2059 C CG  . LYS B 2 29  ? 117.772 135.847 128.961 1.00 55.79 ? 29  LYS B CG  1 
ATOM   2060 C CD  . LYS B 2 29  ? 117.440 135.956 127.471 1.00 60.82 ? 29  LYS B CD  1 
ATOM   2061 C CE  . LYS B 2 29  ? 116.863 134.648 126.937 1.00 57.35 ? 29  LYS B CE  1 
ATOM   2062 N NZ  . LYS B 2 29  ? 117.884 133.565 126.837 1.00 57.50 ? 29  LYS B NZ  1 
ATOM   2063 N N   . ALA B 2 30  ? 121.331 134.385 129.941 1.00 58.54 ? 30  ALA B N   1 
ATOM   2064 C CA  . ALA B 2 30  ? 121.768 133.023 129.642 1.00 57.77 ? 30  ALA B CA  1 
ATOM   2065 C C   . ALA B 2 30  ? 122.038 132.221 130.910 1.00 57.51 ? 30  ALA B C   1 
ATOM   2066 O O   . ALA B 2 30  ? 121.825 131.003 130.934 1.00 54.95 ? 30  ALA B O   1 
ATOM   2067 C CB  . ALA B 2 30  ? 123.018 133.056 128.764 1.00 58.13 ? 30  ALA B CB  1 
ATOM   2068 N N   . ARG B 2 31  ? 122.526 132.876 131.968 1.00 59.81 ? 31  ARG B N   1 
ATOM   2069 C CA  . ARG B 2 31  ? 122.866 132.139 133.187 1.00 59.29 ? 31  ARG B CA  1 
ATOM   2070 C C   . ARG B 2 31  ? 121.633 131.525 133.845 1.00 59.45 ? 31  ARG B C   1 
ATOM   2071 O O   . ARG B 2 31  ? 121.741 130.515 134.550 1.00 57.65 ? 31  ARG B O   1 
ATOM   2072 C CB  . ARG B 2 31  ? 123.586 133.040 134.193 1.00 57.93 ? 31  ARG B CB  1 
ATOM   2073 C CG  . ARG B 2 31  ? 125.075 132.760 134.331 1.00 59.86 ? 31  ARG B CG  1 
ATOM   2074 C CD  . ARG B 2 31  ? 125.673 133.439 135.558 1.00 62.60 ? 31  ARG B CD  1 
ATOM   2075 N NE  . ARG B 2 31  ? 125.774 134.888 135.405 1.00 64.57 ? 31  ARG B NE  1 
ATOM   2076 C CZ  . ARG B 2 31  ? 124.837 135.774 135.731 1.00 63.47 ? 31  ARG B CZ  1 
ATOM   2077 N NH1 . ARG B 2 31  ? 123.678 135.411 136.263 1.00 62.64 ? 31  ARG B NH1 1 
ATOM   2078 N NH2 . ARG B 2 31  ? 125.070 137.066 135.518 1.00 60.87 ? 31  ARG B NH2 1 
ATOM   2079 N N   . ARG B 2 32  ? 120.459 132.132 133.649 1.00 59.44 ? 32  ARG B N   1 
ATOM   2080 C CA  . ARG B 2 32  ? 119.245 131.640 134.297 1.00 59.56 ? 32  ARG B CA  1 
ATOM   2081 C C   . ARG B 2 32  ? 118.898 130.229 133.834 1.00 59.61 ? 32  ARG B C   1 
ATOM   2082 O O   . ARG B 2 32  ? 118.453 129.393 134.629 1.00 59.01 ? 32  ARG B O   1 
ATOM   2083 C CB  . ARG B 2 32  ? 118.085 132.596 134.019 1.00 55.42 ? 32  ARG B CB  1 
ATOM   2084 N N   . THR B 2 33  ? 119.088 129.948 132.550 1.00 60.24 ? 33  THR B N   1 
ATOM   2085 C CA  . THR B 2 33  ? 118.733 128.649 132.000 1.00 58.84 ? 33  THR B CA  1 
ATOM   2086 C C   . THR B 2 33  ? 119.748 127.582 132.404 1.00 58.98 ? 33  THR B C   1 
ATOM   2087 O O   . THR B 2 33  ? 120.946 127.848 132.532 1.00 56.99 ? 33  THR B O   1 
ATOM   2088 C CB  . THR B 2 33  ? 118.649 128.734 130.476 1.00 58.25 ? 33  THR B CB  1 
ATOM   2089 O OG1 . THR B 2 33  ? 117.882 129.884 130.103 1.00 60.75 ? 33  THR B OG1 1 
ATOM   2090 C CG2 . THR B 2 33  ? 117.993 127.499 129.893 1.00 56.10 ? 33  THR B CG2 1 
ATOM   2091 N N   . LEU B 2 34  ? 119.247 126.362 132.596 1.00 52.75 ? 34  LEU B N   1 
ATOM   2092 C CA  . LEU B 2 34  ? 120.060 125.169 132.803 1.00 49.69 ? 34  LEU B CA  1 
ATOM   2093 C C   . LEU B 2 34  ? 119.954 124.310 131.551 1.00 50.01 ? 34  LEU B C   1 
ATOM   2094 O O   . LEU B 2 34  ? 118.851 124.083 131.048 1.00 51.97 ? 34  LEU B O   1 
ATOM   2095 C CB  . LEU B 2 34  ? 119.590 124.381 134.031 1.00 47.17 ? 34  LEU B CB  1 
ATOM   2096 C CG  . LEU B 2 34  ? 119.735 124.982 135.438 1.00 50.29 ? 34  LEU B CG  1 
ATOM   2097 C CD1 . LEU B 2 34  ? 119.627 123.885 136.478 1.00 48.88 ? 34  LEU B CD1 1 
ATOM   2098 C CD2 . LEU B 2 34  ? 121.035 125.747 135.639 1.00 53.72 ? 34  LEU B CD2 1 
ATOM   2099 N N   . ARG B 2 35  ? 121.093 123.838 131.054 1.00 52.58 ? 35  ARG B N   1 
ATOM   2100 C CA  . ARG B 2 35  ? 121.194 123.259 129.720 1.00 49.52 ? 35  ARG B CA  1 
ATOM   2101 C C   . ARG B 2 35  ? 121.504 121.773 129.834 1.00 49.81 ? 35  ARG B C   1 
ATOM   2102 O O   . ARG B 2 35  ? 122.378 121.378 130.612 1.00 53.57 ? 35  ARG B O   1 
ATOM   2103 C CB  . ARG B 2 35  ? 122.276 123.988 128.921 1.00 49.87 ? 35  ARG B CB  1 
ATOM   2104 C CG  . ARG B 2 35  ? 121.914 125.449 128.650 1.00 54.43 ? 35  ARG B CG  1 
ATOM   2105 C CD  . ARG B 2 35  ? 122.266 125.917 127.235 1.00 51.18 ? 35  ARG B CD  1 
ATOM   2106 N NE  . ARG B 2 35  ? 123.680 125.811 126.882 1.00 54.77 ? 35  ARG B NE  1 
ATOM   2107 C CZ  . ARG B 2 35  ? 124.692 126.413 127.499 1.00 55.61 ? 35  ARG B CZ  1 
ATOM   2108 N NH1 . ARG B 2 35  ? 124.503 127.286 128.477 1.00 51.30 ? 35  ARG B NH1 1 
ATOM   2109 N NH2 . ARG B 2 35  ? 125.934 126.154 127.102 1.00 56.63 ? 35  ARG B NH2 1 
ATOM   2110 N N   . LEU B 2 36  ? 120.784 120.957 129.062 1.00 47.60 ? 36  LEU B N   1 
ATOM   2111 C CA  . LEU B 2 36  ? 120.843 119.501 129.141 1.00 43.92 ? 36  LEU B CA  1 
ATOM   2112 C C   . LEU B 2 36  ? 121.019 118.909 127.750 1.00 42.33 ? 36  LEU B C   1 
ATOM   2113 O O   . LEU B 2 36  ? 120.571 119.492 126.759 1.00 53.05 ? 36  LEU B O   1 
ATOM   2114 C CB  . LEU B 2 36  ? 119.572 118.926 129.780 1.00 45.41 ? 36  LEU B CB  1 
ATOM   2115 C CG  . LEU B 2 36  ? 119.159 119.470 131.151 1.00 40.90 ? 36  LEU B CG  1 
ATOM   2116 C CD1 . LEU B 2 36  ? 117.680 119.264 131.398 1.00 42.95 ? 36  LEU B CD1 1 
ATOM   2117 C CD2 . LEU B 2 36  ? 119.974 118.806 132.241 1.00 41.43 ? 36  LEU B CD2 1 
ATOM   2118 N N   . LEU B 2 37  ? 121.673 117.749 127.689 1.00 36.45 ? 37  LEU B N   1 
ATOM   2119 C CA  . LEU B 2 37  ? 121.922 117.018 126.452 1.00 42.19 ? 37  LEU B CA  1 
ATOM   2120 C C   . LEU B 2 37  ? 121.278 115.641 126.549 1.00 39.85 ? 37  LEU B C   1 
ATOM   2121 O O   . LEU B 2 37  ? 121.508 114.918 127.522 1.00 52.98 ? 37  LEU B O   1 
ATOM   2122 C CB  . LEU B 2 37  ? 123.426 116.890 126.194 1.00 39.93 ? 37  LEU B CB  1 
ATOM   2123 C CG  . LEU B 2 37  ? 123.914 115.936 125.098 1.00 40.15 ? 37  LEU B CG  1 
ATOM   2124 C CD1 . LEU B 2 37  ? 123.273 116.269 123.768 1.00 43.18 ? 37  LEU B CD1 1 
ATOM   2125 C CD2 . LEU B 2 37  ? 125.421 115.989 124.981 1.00 44.52 ? 37  LEU B CD2 1 
ATOM   2126 N N   . LEU B 2 38  ? 120.491 115.281 125.537 1.00 38.57 ? 38  LEU B N   1 
ATOM   2127 C CA  . LEU B 2 38  ? 119.790 114.003 125.473 1.00 38.72 ? 38  LEU B CA  1 
ATOM   2128 C C   . LEU B 2 38  ? 120.514 113.095 124.486 1.00 48.06 ? 38  LEU B C   1 
ATOM   2129 O O   . LEU B 2 38  ? 120.803 113.512 123.360 1.00 59.39 ? 38  LEU B O   1 
ATOM   2130 C CB  . LEU B 2 38  ? 118.334 114.208 125.053 1.00 39.46 ? 38  LEU B CB  1 
ATOM   2131 C CG  . LEU B 2 38  ? 117.450 112.967 124.870 1.00 42.28 ? 38  LEU B CG  1 
ATOM   2132 C CD1 . LEU B 2 38  ? 117.325 112.207 126.173 1.00 48.23 ? 38  LEU B CD1 1 
ATOM   2133 C CD2 . LEU B 2 38  ? 116.069 113.341 124.361 1.00 49.46 ? 38  LEU B CD2 1 
ATOM   2134 N N   . LEU B 2 39  ? 120.807 111.863 124.910 1.00 40.06 ? 39  LEU B N   1 
ATOM   2135 C CA  . LEU B 2 39  ? 121.461 110.864 124.070 1.00 38.60 ? 39  LEU B CA  1 
ATOM   2136 C C   . LEU B 2 39  ? 120.770 109.518 124.234 1.00 39.00 ? 39  LEU B C   1 
ATOM   2137 O O   . LEU B 2 39  ? 120.710 108.978 125.341 1.00 37.28 ? 39  LEU B O   1 
ATOM   2138 C CB  . LEU B 2 39  ? 122.948 110.736 124.410 1.00 36.30 ? 39  LEU B CB  1 
ATOM   2139 C CG  . LEU B 2 39  ? 123.782 112.016 124.472 1.00 40.71 ? 39  LEU B CG  1 
ATOM   2140 C CD1 . LEU B 2 39  ? 125.128 111.740 125.105 1.00 40.76 ? 39  LEU B CD1 1 
ATOM   2141 C CD2 . LEU B 2 39  ? 123.969 112.604 123.086 1.00 48.53 ? 39  LEU B CD2 1 
ATOM   2142 N N   . GLY B 2 40  ? 120.251 108.985 123.132 1.00 50.91 ? 40  GLY B N   1 
ATOM   2143 C CA  . GLY B 2 40  ? 119.758 107.622 123.078 1.00 49.30 ? 40  GLY B CA  1 
ATOM   2144 C C   . GLY B 2 40  ? 119.986 107.054 121.693 1.00 50.90 ? 40  GLY B C   1 
ATOM   2145 O O   . GLY B 2 40  ? 119.692 107.729 120.703 1.00 51.87 ? 40  GLY B O   1 
ATOM   2146 N N   . ALA B 2 41  ? 120.533 105.837 121.601 1.00 62.83 ? 41  ALA B N   1 
ATOM   2147 C CA  . ALA B 2 41  ? 120.934 105.302 120.301 1.00 67.53 ? 41  ALA B CA  1 
ATOM   2148 C C   . ALA B 2 41  ? 119.736 105.101 119.380 1.00 64.82 ? 41  ALA B C   1 
ATOM   2149 O O   . ALA B 2 41  ? 119.580 105.815 118.383 1.00 65.53 ? 41  ALA B O   1 
ATOM   2150 C CB  . ALA B 2 41  ? 121.688 103.985 120.492 1.00 64.25 ? 41  ALA B CB  1 
ATOM   2151 N N   . ASP B 2 42  ? 118.866 104.153 119.717 1.00 67.08 ? 42  ASP B N   1 
ATOM   2152 C CA  . ASP B 2 42  ? 117.618 103.894 119.008 1.00 67.78 ? 42  ASP B CA  1 
ATOM   2153 C C   . ASP B 2 42  ? 116.892 102.815 119.794 1.00 68.99 ? 42  ASP B C   1 
ATOM   2154 O O   . ASP B 2 42  ? 117.520 102.013 120.491 1.00 69.21 ? 42  ASP B O   1 
ATOM   2155 C CB  . ASP B 2 42  ? 117.837 103.446 117.555 1.00 70.88 ? 42  ASP B CB  1 
ATOM   2156 C CG  . ASP B 2 42  ? 116.559 103.486 116.733 1.00 72.32 ? 42  ASP B CG  1 
ATOM   2157 O OD1 . ASP B 2 42  ? 115.471 103.675 117.316 1.00 70.30 ? 42  ASP B OD1 1 
ATOM   2158 O OD2 . ASP B 2 42  ? 116.646 103.327 115.497 1.00 71.16 ? 42  ASP B OD2 1 
ATOM   2159 N N   . ASN B 2 43  ? 115.564 102.821 119.691 1.00 60.18 ? 43  ASN B N   1 
ATOM   2160 C CA  . ASN B 2 43  ? 114.636 102.021 120.490 1.00 61.55 ? 43  ASN B CA  1 
ATOM   2161 C C   . ASN B 2 43  ? 114.590 102.570 121.920 1.00 63.23 ? 43  ASN B C   1 
ATOM   2162 O O   . ASN B 2 43  ? 113.986 101.925 122.788 1.00 61.25 ? 43  ASN B O   1 
ATOM   2163 C CB  . ASN B 2 43  ? 115.010 100.525 120.516 1.00 59.86 ? 43  ASN B CB  1 
ATOM   2164 C CG  . ASN B 2 43  ? 114.773 99.790  119.177 1.00 65.26 ? 43  ASN B CG  1 
ATOM   2165 O OD1 . ASN B 2 43  ? 113.959 100.254 118.380 1.00 65.10 ? 43  ASN B OD1 1 
ATOM   2166 N ND2 . ASN B 2 43  ? 115.472 98.680  118.915 1.00 65.69 ? 43  ASN B ND2 1 
ATOM   2167 N N   . SER B 2 44  ? 115.196 103.728 122.199 1.00 54.37 ? 44  SER B N   1 
ATOM   2168 C CA  . SER B 2 44  ? 115.241 104.241 123.560 1.00 46.99 ? 44  SER B CA  1 
ATOM   2169 C C   . SER B 2 44  ? 113.907 104.849 123.971 1.00 55.16 ? 44  SER B C   1 
ATOM   2170 O O   . SER B 2 44  ? 113.538 104.807 125.150 1.00 59.42 ? 44  SER B O   1 
ATOM   2171 C CB  . SER B 2 44  ? 116.358 105.275 123.676 1.00 51.20 ? 44  SER B CB  1 
ATOM   2172 O OG  . SER B 2 44  ? 117.591 104.740 123.233 1.00 48.10 ? 44  SER B OG  1 
ATOM   2173 N N   . GLY B 2 45  ? 113.175 105.421 123.020 1.00 55.79 ? 45  GLY B N   1 
ATOM   2174 C CA  . GLY B 2 45  ? 112.051 106.272 123.374 1.00 50.99 ? 45  GLY B CA  1 
ATOM   2175 C C   . GLY B 2 45  ? 112.516 107.545 124.044 1.00 45.43 ? 45  GLY B C   1 
ATOM   2176 O O   . GLY B 2 45  ? 111.824 108.080 124.918 1.00 48.03 ? 45  GLY B O   1 
ATOM   2177 N N   . LYS B 2 46  ? 113.684 108.045 123.639 1.00 39.90 ? 46  LYS B N   1 
ATOM   2178 C CA  . LYS B 2 46  ? 114.287 109.195 124.305 1.00 47.08 ? 46  LYS B CA  1 
ATOM   2179 C C   . LYS B 2 46  ? 113.470 110.463 124.091 1.00 53.73 ? 46  LYS B C   1 
ATOM   2180 O O   . LYS B 2 46  ? 113.452 111.349 124.954 1.00 57.33 ? 46  LYS B O   1 
ATOM   2181 C CB  . LYS B 2 46  ? 115.723 109.378 123.809 1.00 44.95 ? 46  LYS B CB  1 
ATOM   2182 C CG  . LYS B 2 46  ? 115.849 109.710 122.325 1.00 48.33 ? 46  LYS B CG  1 
ATOM   2183 C CD  . LYS B 2 46  ? 117.305 109.698 121.868 1.00 50.01 ? 46  LYS B CD  1 
ATOM   2184 C CE  . LYS B 2 46  ? 117.524 110.519 120.605 1.00 49.15 ? 46  LYS B CE  1 
ATOM   2185 N NZ  . LYS B 2 46  ? 118.960 110.827 120.365 1.00 46.40 ? 46  LYS B NZ  1 
ATOM   2186 N N   . SER B 2 47  ? 112.802 110.580 122.942 1.00 52.38 ? 47  SER B N   1 
ATOM   2187 C CA  . SER B 2 47  ? 112.013 111.778 122.670 1.00 50.92 ? 47  SER B CA  1 
ATOM   2188 C C   . SER B 2 47  ? 110.845 111.909 123.641 1.00 55.86 ? 47  SER B C   1 
ATOM   2189 O O   . SER B 2 47  ? 110.462 113.025 124.013 1.00 52.77 ? 47  SER B O   1 
ATOM   2190 C CB  . SER B 2 47  ? 111.510 111.755 121.227 1.00 51.51 ? 47  SER B CB  1 
ATOM   2191 O OG  . SER B 2 47  ? 110.891 110.518 120.920 1.00 52.18 ? 47  SER B OG  1 
ATOM   2192 N N   . THR B 2 48  ? 110.273 110.784 124.066 1.00 58.44 ? 48  THR B N   1 
ATOM   2193 C CA  . THR B 2 48  ? 109.086 110.759 124.911 1.00 56.21 ? 48  THR B CA  1 
ATOM   2194 C C   . THR B 2 48  ? 109.410 110.644 126.400 1.00 53.65 ? 48  THR B C   1 
ATOM   2195 O O   . THR B 2 48  ? 108.524 110.297 127.185 1.00 57.11 ? 48  THR B O   1 
ATOM   2196 C CB  . THR B 2 48  ? 108.181 109.593 124.480 1.00 56.40 ? 48  THR B CB  1 
ATOM   2197 O OG1 . THR B 2 48  ? 108.270 109.426 123.060 1.00 53.73 ? 48  THR B OG1 1 
ATOM   2198 C CG2 . THR B 2 48  ? 106.710 109.845 124.844 1.00 57.34 ? 48  THR B CG2 1 
ATOM   2199 N N   . ILE B 2 49  ? 110.653 110.909 126.812 1.00 49.43 ? 49  ILE B N   1 
ATOM   2200 C CA  . ILE B 2 49  ? 110.992 110.820 128.231 1.00 52.20 ? 49  ILE B CA  1 
ATOM   2201 C C   . ILE B 2 49  ? 110.263 111.905 129.017 1.00 57.50 ? 49  ILE B C   1 
ATOM   2202 O O   . ILE B 2 49  ? 109.633 111.627 130.045 1.00 57.75 ? 49  ILE B O   1 
ATOM   2203 C CB  . ILE B 2 49  ? 112.523 110.903 128.420 1.00 50.54 ? 49  ILE B CB  1 
ATOM   2204 C CG1 . ILE B 2 49  ? 113.198 109.572 128.065 1.00 51.65 ? 49  ILE B CG1 1 
ATOM   2205 C CG2 . ILE B 2 49  ? 112.908 111.285 129.857 1.00 52.39 ? 49  ILE B CG2 1 
ATOM   2206 C CD1 . ILE B 2 49  ? 113.046 108.450 129.093 1.00 52.17 ? 49  ILE B CD1 1 
ATOM   2207 N N   . VAL B 2 50  ? 110.327 113.148 128.544 1.00 58.85 ? 50  VAL B N   1 
ATOM   2208 C CA  . VAL B 2 50  ? 109.694 114.291 129.198 1.00 58.52 ? 50  VAL B CA  1 
ATOM   2209 C C   . VAL B 2 50  ? 108.370 114.540 128.487 1.00 61.86 ? 50  VAL B C   1 
ATOM   2210 O O   . VAL B 2 50  ? 108.338 115.075 127.373 1.00 64.08 ? 50  VAL B O   1 
ATOM   2211 C CB  . VAL B 2 50  ? 110.595 115.533 129.171 1.00 56.58 ? 50  VAL B CB  1 
ATOM   2212 C CG1 . VAL B 2 50  ? 109.931 116.694 129.911 1.00 57.45 ? 50  VAL B CG1 1 
ATOM   2213 C CG2 . VAL B 2 50  ? 111.960 115.211 129.781 1.00 54.34 ? 50  VAL B CG2 1 
ATOM   2214 N N   . LYS B 2 51  ? 107.273 114.159 129.142 1.00 69.46 ? 51  LYS B N   1 
ATOM   2215 C CA  . LYS B 2 51  ? 105.971 114.137 128.482 1.00 71.53 ? 51  LYS B CA  1 
ATOM   2216 C C   . LYS B 2 51  ? 105.427 115.539 128.237 1.00 74.77 ? 51  LYS B C   1 
ATOM   2217 O O   . LYS B 2 51  ? 104.775 115.783 127.215 1.00 71.08 ? 51  LYS B O   1 
ATOM   2218 C CB  . LYS B 2 51  ? 104.973 113.336 129.321 1.00 71.85 ? 51  LYS B CB  1 
ATOM   2219 C CG  . LYS B 2 51  ? 105.397 111.895 129.654 1.00 70.67 ? 51  LYS B CG  1 
ATOM   2220 C CD  . LYS B 2 51  ? 105.449 110.973 128.427 1.00 73.75 ? 51  LYS B CD  1 
ATOM   2221 C CE  . LYS B 2 51  ? 104.117 110.843 127.677 1.00 72.28 ? 51  LYS B CE  1 
ATOM   2222 N NZ  . LYS B 2 51  ? 102.906 110.821 128.553 1.00 69.42 ? 51  LYS B NZ  1 
ATOM   2223 N N   . GLN B 2 52  ? 105.676 116.467 129.166 1.00 81.64 ? 52  GLN B N   1 
ATOM   2224 C CA  . GLN B 2 52  ? 104.875 117.687 129.244 1.00 79.31 ? 52  GLN B CA  1 
ATOM   2225 C C   . GLN B 2 52  ? 105.062 118.586 128.026 1.00 79.71 ? 52  GLN B C   1 
ATOM   2226 O O   . GLN B 2 52  ? 104.078 119.047 127.436 1.00 79.60 ? 52  GLN B O   1 
ATOM   2227 C CB  . GLN B 2 52  ? 105.222 118.453 130.521 1.00 75.62 ? 52  GLN B CB  1 
ATOM   2228 N N   . MET B 2 53  ? 106.309 118.828 127.623 1.00 76.82 ? 53  MET B N   1 
ATOM   2229 C CA  . MET B 2 53  ? 106.652 119.919 126.718 1.00 78.38 ? 53  MET B CA  1 
ATOM   2230 C C   . MET B 2 53  ? 107.308 119.387 125.453 1.00 78.38 ? 53  MET B C   1 
ATOM   2231 O O   . MET B 2 53  ? 108.433 118.877 125.497 1.00 79.26 ? 53  MET B O   1 
ATOM   2232 C CB  . MET B 2 53  ? 107.586 120.915 127.411 1.00 76.17 ? 53  MET B CB  1 
ATOM   2233 C CG  . MET B 2 53  ? 106.993 121.578 128.655 1.00 79.15 ? 53  MET B CG  1 
ATOM   2234 S SD  . MET B 2 53  ? 106.459 123.274 128.361 1.00 80.85 ? 53  MET B SD  1 
ATOM   2235 C CE  . MET B 2 53  ? 105.379 123.531 129.767 1.00 75.66 ? 53  MET B CE  1 
ATOM   2236 N N   . ARG B 2 54  ? 106.602 119.519 124.333 1.00 81.33 ? 54  ARG B N   1 
ATOM   2237 C CA  . ARG B 2 54  ? 107.168 119.302 123.005 1.00 81.21 ? 54  ARG B CA  1 
ATOM   2238 C C   . ARG B 2 54  ? 106.221 119.842 121.939 1.00 77.72 ? 54  ARG B C   1 
ATOM   2239 O O   . ARG B 2 54  ? 105.066 120.156 122.224 1.00 77.19 ? 54  ARG B O   1 
ATOM   2240 C CB  . ARG B 2 54  ? 107.448 117.810 122.746 1.00 80.85 ? 54  ARG B CB  1 
ATOM   2241 C CG  . ARG B 2 54  ? 108.310 117.488 121.506 1.00 79.57 ? 54  ARG B CG  1 
ATOM   2242 C CD  . ARG B 2 54  ? 109.604 118.291 121.406 1.00 80.52 ? 54  ARG B CD  1 
ATOM   2243 N NE  . ARG B 2 54  ? 110.549 117.698 120.464 1.00 83.02 ? 54  ARG B NE  1 
ATOM   2244 C CZ  . ARG B 2 54  ? 111.554 118.340 119.878 1.00 80.35 ? 54  ARG B CZ  1 
ATOM   2245 N NH1 . ARG B 2 54  ? 111.818 119.614 120.133 1.00 78.48 ? 54  ARG B NH1 1 
ATOM   2246 N NH2 . ARG B 2 54  ? 112.317 117.686 119.008 1.00 75.85 ? 54  ARG B NH2 1 
ATOM   2247 N N   . THR B 2 66  ? 114.563 122.530 111.632 1.00 68.29 ? 66  THR B N   1 
ATOM   2248 C CA  . THR B 2 66  ? 115.598 122.338 112.641 1.00 72.69 ? 66  THR B CA  1 
ATOM   2249 C C   . THR B 2 66  ? 116.120 120.904 112.584 1.00 70.34 ? 66  THR B C   1 
ATOM   2250 O O   . THR B 2 66  ? 116.006 120.146 113.547 1.00 69.33 ? 66  THR B O   1 
ATOM   2251 C CB  . THR B 2 66  ? 115.069 122.643 114.057 1.00 71.48 ? 66  THR B CB  1 
ATOM   2252 O OG1 . THR B 2 66  ? 113.851 121.925 114.287 1.00 72.17 ? 66  THR B OG1 1 
ATOM   2253 C CG2 . THR B 2 66  ? 114.814 124.129 114.222 1.00 70.57 ? 66  THR B CG2 1 
ATOM   2254 N N   . SER B 2 67  ? 116.688 120.538 111.432 1.00 69.83 ? 67  SER B N   1 
ATOM   2255 C CA  . SER B 2 67  ? 117.189 119.180 111.250 1.00 70.33 ? 67  SER B CA  1 
ATOM   2256 C C   . SER B 2 67  ? 118.462 118.943 112.053 1.00 68.61 ? 67  SER B C   1 
ATOM   2257 O O   . SER B 2 67  ? 118.665 117.853 112.603 1.00 67.04 ? 67  SER B O   1 
ATOM   2258 C CB  . SER B 2 67  ? 117.440 118.910 109.766 1.00 66.60 ? 67  SER B CB  1 
ATOM   2259 O OG  . SER B 2 67  ? 118.426 119.786 109.251 1.00 65.96 ? 67  SER B OG  1 
ATOM   2260 N N   . GLY B 2 68  ? 119.339 119.947 112.120 1.00 61.27 ? 68  GLY B N   1 
ATOM   2261 C CA  . GLY B 2 68  ? 120.623 119.752 112.772 1.00 62.83 ? 68  GLY B CA  1 
ATOM   2262 C C   . GLY B 2 68  ? 120.509 119.496 114.262 1.00 65.56 ? 68  GLY B C   1 
ATOM   2263 O O   . GLY B 2 68  ? 121.221 118.653 114.810 1.00 69.54 ? 68  GLY B O   1 
ATOM   2264 N N   . ILE B 2 69  ? 119.619 120.222 114.937 1.00 61.58 ? 69  ILE B N   1 
ATOM   2265 C CA  . ILE B 2 69  ? 119.453 120.132 116.382 1.00 58.40 ? 69  ILE B CA  1 
ATOM   2266 C C   . ILE B 2 69  ? 117.968 120.236 116.700 1.00 63.94 ? 69  ILE B C   1 
ATOM   2267 O O   . ILE B 2 69  ? 117.251 121.069 116.140 1.00 69.28 ? 69  ILE B O   1 
ATOM   2268 C CB  . ILE B 2 69  ? 120.305 121.222 117.091 1.00 57.93 ? 69  ILE B CB  1 
ATOM   2269 C CG1 . ILE B 2 69  ? 121.711 120.659 117.328 1.00 56.78 ? 69  ILE B CG1 1 
ATOM   2270 C CG2 . ILE B 2 69  ? 119.652 121.724 118.414 1.00 63.00 ? 69  ILE B CG2 1 
ATOM   2271 C CD1 . ILE B 2 69  ? 122.740 121.630 117.849 1.00 59.99 ? 69  ILE B CD1 1 
ATOM   2272 N N   . PHE B 2 70  ? 117.516 119.379 117.611 1.00 60.83 ? 70  PHE B N   1 
ATOM   2273 C CA  . PHE B 2 70  ? 116.155 119.388 118.126 1.00 62.48 ? 70  PHE B CA  1 
ATOM   2274 C C   . PHE B 2 70  ? 116.189 119.860 119.571 1.00 65.19 ? 70  PHE B C   1 
ATOM   2275 O O   . PHE B 2 70  ? 116.966 119.343 120.380 1.00 67.17 ? 70  PHE B O   1 
ATOM   2276 C CB  . PHE B 2 70  ? 115.525 117.997 118.034 1.00 60.60 ? 70  PHE B CB  1 
ATOM   2277 N N   . GLU B 2 71  ? 115.350 120.848 119.885 1.00 67.72 ? 71  GLU B N   1 
ATOM   2278 C CA  . GLU B 2 71  ? 115.380 121.559 121.157 1.00 62.59 ? 71  GLU B CA  1 
ATOM   2279 C C   . GLU B 2 71  ? 113.987 121.586 121.765 1.00 63.29 ? 71  GLU B C   1 
ATOM   2280 O O   . GLU B 2 71  ? 113.001 121.791 121.050 1.00 67.91 ? 71  GLU B O   1 
ATOM   2281 C CB  . GLU B 2 71  ? 115.897 122.988 120.958 1.00 64.40 ? 71  GLU B CB  1 
ATOM   2282 C CG  . GLU B 2 71  ? 116.517 123.645 122.211 1.00 67.95 ? 71  GLU B CG  1 
ATOM   2283 C CD  . GLU B 2 71  ? 115.609 124.635 122.945 1.00 71.81 ? 71  GLU B CD  1 
ATOM   2284 O OE1 . GLU B 2 71  ? 114.489 124.929 122.479 1.00 74.99 ? 71  GLU B OE1 1 
ATOM   2285 O OE2 . GLU B 2 71  ? 116.030 125.129 124.012 1.00 64.67 ? 71  GLU B OE2 1 
ATOM   2286 N N   . THR B 2 72  ? 113.910 121.371 123.078 1.00 64.11 ? 72  THR B N   1 
ATOM   2287 C CA  . THR B 2 72  ? 112.671 121.476 123.840 1.00 69.16 ? 72  THR B CA  1 
ATOM   2288 C C   . THR B 2 72  ? 112.939 122.246 125.125 1.00 67.95 ? 72  THR B C   1 
ATOM   2289 O O   . THR B 2 72  ? 114.040 122.168 125.681 1.00 64.45 ? 72  THR B O   1 
ATOM   2290 C CB  . THR B 2 72  ? 112.080 120.094 124.160 1.00 67.08 ? 72  THR B CB  1 
ATOM   2291 O OG1 . THR B 2 72  ? 110.852 120.252 124.881 1.00 66.31 ? 72  THR B OG1 1 
ATOM   2292 C CG2 . THR B 2 72  ? 113.039 119.238 124.983 1.00 66.64 ? 72  THR B CG2 1 
ATOM   2293 N N   . LYS B 2 73  ? 111.931 122.984 125.588 1.00 70.07 ? 73  LYS B N   1 
ATOM   2294 C CA  . LYS B 2 73  ? 111.997 123.773 126.812 1.00 66.19 ? 73  LYS B CA  1 
ATOM   2295 C C   . LYS B 2 73  ? 110.923 123.271 127.765 1.00 68.45 ? 73  LYS B C   1 
ATOM   2296 O O   . LYS B 2 73  ? 109.756 123.160 127.375 1.00 70.19 ? 73  LYS B O   1 
ATOM   2297 C CB  . LYS B 2 73  ? 111.772 125.262 126.526 1.00 67.95 ? 73  LYS B CB  1 
ATOM   2298 C CG  . LYS B 2 73  ? 112.771 125.908 125.568 1.00 67.87 ? 73  LYS B CG  1 
ATOM   2299 C CD  . LYS B 2 73  ? 112.113 127.033 124.778 1.00 68.74 ? 73  LYS B CD  1 
ATOM   2300 C CE  . LYS B 2 73  ? 111.437 126.522 123.513 1.00 68.87 ? 73  LYS B CE  1 
ATOM   2301 N NZ  . LYS B 2 73  ? 112.395 126.182 122.429 1.00 66.55 ? 73  LYS B NZ  1 
ATOM   2302 N N   . PHE B 2 74  ? 111.310 122.965 129.006 1.00 59.76 ? 74  PHE B N   1 
ATOM   2303 C CA  . PHE B 2 74  ? 110.361 122.572 130.039 1.00 59.36 ? 74  PHE B CA  1 
ATOM   2304 C C   . PHE B 2 74  ? 110.734 123.224 131.363 1.00 60.31 ? 74  PHE B C   1 
ATOM   2305 O O   . PHE B 2 74  ? 111.911 123.468 131.643 1.00 64.05 ? 74  PHE B O   1 
ATOM   2306 C CB  . PHE B 2 74  ? 110.275 121.032 130.177 1.00 63.04 ? 74  PHE B CB  1 
ATOM   2307 C CG  . PHE B 2 74  ? 111.507 120.381 130.747 1.00 62.65 ? 74  PHE B CG  1 
ATOM   2308 C CD1 . PHE B 2 74  ? 112.542 119.988 129.919 1.00 60.60 ? 74  PHE B CD1 1 
ATOM   2309 C CD2 . PHE B 2 74  ? 111.601 120.106 132.102 1.00 61.24 ? 74  PHE B CD2 1 
ATOM   2310 C CE1 . PHE B 2 74  ? 113.663 119.372 130.434 1.00 60.16 ? 74  PHE B CE1 1 
ATOM   2311 C CE2 . PHE B 2 74  ? 112.719 119.491 132.622 1.00 60.58 ? 74  PHE B CE2 1 
ATOM   2312 C CZ  . PHE B 2 74  ? 113.749 119.120 131.787 1.00 62.65 ? 74  PHE B CZ  1 
ATOM   2313 N N   . GLN B 2 75  ? 109.707 123.513 132.165 1.00 61.46 ? 75  GLN B N   1 
ATOM   2314 C CA  . GLN B 2 75  ? 109.839 124.210 133.439 1.00 61.38 ? 75  GLN B CA  1 
ATOM   2315 C C   . GLN B 2 75  ? 109.192 123.385 134.541 1.00 64.34 ? 75  GLN B C   1 
ATOM   2316 O O   . GLN B 2 75  ? 108.060 122.916 134.386 1.00 66.33 ? 75  GLN B O   1 
ATOM   2317 C CB  . GLN B 2 75  ? 109.185 125.597 133.387 1.00 65.00 ? 75  GLN B CB  1 
ATOM   2318 C CG  . GLN B 2 75  ? 109.341 126.432 134.668 1.00 67.97 ? 75  GLN B CG  1 
ATOM   2319 C CD  . GLN B 2 75  ? 108.604 127.749 134.599 1.00 66.17 ? 75  GLN B CD  1 
ATOM   2320 O OE1 . GLN B 2 75  ? 109.215 128.815 134.527 1.00 61.92 ? 75  GLN B OE1 1 
ATOM   2321 N NE2 . GLN B 2 75  ? 107.277 127.683 134.630 1.00 64.76 ? 75  GLN B NE2 1 
ATOM   2322 N N   . VAL B 2 76  ? 109.909 123.221 135.650 1.00 60.72 ? 76  VAL B N   1 
ATOM   2323 C CA  . VAL B 2 76  ? 109.363 122.670 136.884 1.00 62.16 ? 76  VAL B CA  1 
ATOM   2324 C C   . VAL B 2 76  ? 109.883 123.505 138.050 1.00 64.96 ? 76  VAL B C   1 
ATOM   2325 O O   . VAL B 2 76  ? 111.090 123.756 138.155 1.00 66.44 ? 76  VAL B O   1 
ATOM   2326 C CB  . VAL B 2 76  ? 109.708 121.176 137.050 1.00 61.80 ? 76  VAL B CB  1 
ATOM   2327 C CG1 . VAL B 2 76  ? 109.240 120.386 135.833 1.00 64.45 ? 76  VAL B CG1 1 
ATOM   2328 C CG2 . VAL B 2 76  ? 111.193 120.967 137.281 1.00 58.01 ? 76  VAL B CG2 1 
ATOM   2329 N N   . ASP B 2 77  ? 108.965 123.955 138.906 1.00 67.84 ? 77  ASP B N   1 
ATOM   2330 C CA  . ASP B 2 77  ? 109.300 124.753 140.089 1.00 68.92 ? 77  ASP B CA  1 
ATOM   2331 C C   . ASP B 2 77  ? 110.035 126.039 139.701 1.00 68.19 ? 77  ASP B C   1 
ATOM   2332 O O   . ASP B 2 77  ? 110.974 126.478 140.368 1.00 67.47 ? 77  ASP B O   1 
ATOM   2333 C CB  . ASP B 2 77  ? 110.119 123.919 141.083 1.00 69.33 ? 77  ASP B CB  1 
ATOM   2334 C CG  . ASP B 2 77  ? 110.236 124.569 142.460 1.00 71.63 ? 77  ASP B CG  1 
ATOM   2335 O OD1 . ASP B 2 77  ? 109.429 125.468 142.778 1.00 69.24 ? 77  ASP B OD1 1 
ATOM   2336 O OD2 . ASP B 2 77  ? 111.141 124.174 143.223 1.00 71.82 ? 77  ASP B OD2 1 
ATOM   2337 N N   . LYS B 2 78  ? 109.598 126.652 138.599 1.00 64.08 ? 78  LYS B N   1 
ATOM   2338 C CA  . LYS B 2 78  ? 110.126 127.941 138.147 1.00 67.96 ? 78  LYS B CA  1 
ATOM   2339 C C   . LYS B 2 78  ? 111.619 127.875 137.829 1.00 70.67 ? 78  LYS B C   1 
ATOM   2340 O O   . LYS B 2 78  ? 112.355 128.834 138.074 1.00 67.29 ? 78  LYS B O   1 
ATOM   2341 C CB  . LYS B 2 78  ? 109.857 129.037 139.181 1.00 65.44 ? 78  LYS B CB  1 
ATOM   2342 N N   . VAL B 2 79  ? 112.073 126.740 137.299 1.00 62.82 ? 79  VAL B N   1 
ATOM   2343 C CA  . VAL B 2 79  ? 113.427 126.573 136.781 1.00 57.72 ? 79  VAL B CA  1 
ATOM   2344 C C   . VAL B 2 79  ? 113.307 126.074 135.349 1.00 59.71 ? 79  VAL B C   1 
ATOM   2345 O O   . VAL B 2 79  ? 112.651 125.058 135.099 1.00 59.13 ? 79  VAL B O   1 
ATOM   2346 C CB  . VAL B 2 79  ? 114.253 125.597 137.640 1.00 55.59 ? 79  VAL B CB  1 
ATOM   2347 C CG1 . VAL B 2 79  ? 115.711 125.575 137.181 1.00 59.44 ? 79  VAL B CG1 1 
ATOM   2348 C CG2 . VAL B 2 79  ? 114.156 125.974 139.115 1.00 61.87 ? 79  VAL B CG2 1 
ATOM   2349 N N   . ASN B 2 80  ? 113.947 126.779 134.420 1.00 61.56 ? 80  ASN B N   1 
ATOM   2350 C CA  . ASN B 2 80  ? 113.831 126.503 132.993 1.00 59.44 ? 80  ASN B CA  1 
ATOM   2351 C C   . ASN B 2 80  ? 114.964 125.587 132.551 1.00 59.37 ? 80  ASN B C   1 
ATOM   2352 O O   . ASN B 2 80  ? 116.128 125.832 132.885 1.00 62.78 ? 80  ASN B O   1 
ATOM   2353 C CB  . ASN B 2 80  ? 113.861 127.802 132.187 1.00 61.60 ? 80  ASN B CB  1 
ATOM   2354 C CG  . ASN B 2 80  ? 112.503 128.470 132.105 1.00 63.33 ? 80  ASN B CG  1 
ATOM   2355 O OD1 . ASN B 2 80  ? 112.266 129.498 132.739 1.00 62.37 ? 80  ASN B OD1 1 
ATOM   2356 N ND2 . ASN B 2 80  ? 111.603 127.889 131.320 1.00 64.03 ? 80  ASN B ND2 1 
ATOM   2357 N N   . PHE B 2 81  ? 114.617 124.539 131.801 1.00 52.87 ? 81  PHE B N   1 
ATOM   2358 C CA  . PHE B 2 81  ? 115.564 123.537 131.323 1.00 54.12 ? 81  PHE B CA  1 
ATOM   2359 C C   . PHE B 2 81  ? 115.517 123.462 129.804 1.00 56.96 ? 81  PHE B C   1 
ATOM   2360 O O   . PHE B 2 81  ? 114.433 123.499 129.213 1.00 63.01 ? 81  PHE B O   1 
ATOM   2361 C CB  . PHE B 2 81  ? 115.258 122.161 131.914 1.00 53.78 ? 81  PHE B CB  1 
ATOM   2362 C CG  . PHE B 2 81  ? 115.372 122.102 133.408 1.00 50.04 ? 81  PHE B CG  1 
ATOM   2363 C CD1 . PHE B 2 81  ? 114.290 122.410 134.209 1.00 53.16 ? 81  PHE B CD1 1 
ATOM   2364 C CD2 . PHE B 2 81  ? 116.562 121.749 134.010 1.00 48.48 ? 81  PHE B CD2 1 
ATOM   2365 C CE1 . PHE B 2 81  ? 114.392 122.358 135.582 1.00 55.63 ? 81  PHE B CE1 1 
ATOM   2366 C CE2 . PHE B 2 81  ? 116.670 121.696 135.381 1.00 52.79 ? 81  PHE B CE2 1 
ATOM   2367 C CZ  . PHE B 2 81  ? 115.585 122.003 136.169 1.00 51.71 ? 81  PHE B CZ  1 
ATOM   2368 N N   . HIS B 2 82  ? 116.692 123.362 129.181 1.00 56.57 ? 82  HIS B N   1 
ATOM   2369 C CA  . HIS B 2 82  ? 116.838 123.159 127.743 1.00 57.07 ? 82  HIS B CA  1 
ATOM   2370 C C   . HIS B 2 82  ? 117.442 121.785 127.487 1.00 57.58 ? 82  HIS B C   1 
ATOM   2371 O O   . HIS B 2 82  ? 118.472 121.442 128.075 1.00 60.49 ? 82  HIS B O   1 
ATOM   2372 C CB  . HIS B 2 82  ? 117.728 124.236 127.124 1.00 58.24 ? 82  HIS B CB  1 
ATOM   2373 C CG  . HIS B 2 82  ? 117.063 125.569 126.988 1.00 65.14 ? 82  HIS B CG  1 
ATOM   2374 N ND1 . HIS B 2 82  ? 117.550 126.561 126.164 1.00 65.07 ? 82  HIS B ND1 1 
ATOM   2375 C CD2 . HIS B 2 82  ? 115.947 126.073 127.565 1.00 66.13 ? 82  HIS B CD2 1 
ATOM   2376 C CE1 . HIS B 2 82  ? 116.765 127.621 126.243 1.00 64.46 ? 82  HIS B CE1 1 
ATOM   2377 N NE2 . HIS B 2 82  ? 115.786 127.352 127.087 1.00 65.66 ? 82  HIS B NE2 1 
ATOM   2378 N N   . MET B 2 83  ? 116.807 121.013 126.603 1.00 53.57 ? 83  MET B N   1 
ATOM   2379 C CA  . MET B 2 83  ? 117.222 119.655 126.268 1.00 48.82 ? 83  MET B CA  1 
ATOM   2380 C C   . MET B 2 83  ? 117.579 119.602 124.789 1.00 48.22 ? 83  MET B C   1 
ATOM   2381 O O   . MET B 2 83  ? 116.786 120.027 123.943 1.00 54.30 ? 83  MET B O   1 
ATOM   2382 C CB  . MET B 2 83  ? 116.107 118.652 126.587 1.00 52.40 ? 83  MET B CB  1 
ATOM   2383 C CG  . MET B 2 83  ? 116.546 117.444 127.407 1.00 55.08 ? 83  MET B CG  1 
ATOM   2384 S SD  . MET B 2 83  ? 115.162 116.589 128.185 1.00 55.00 ? 83  MET B SD  1 
ATOM   2385 C CE  . MET B 2 83  ? 114.257 116.031 126.749 1.00 52.83 ? 83  MET B CE  1 
ATOM   2386 N N   . PHE B 2 84  ? 118.766 119.075 124.485 1.00 52.70 ? 84  PHE B N   1 
ATOM   2387 C CA  . PHE B 2 84  ? 119.344 119.096 123.145 1.00 49.87 ? 84  PHE B CA  1 
ATOM   2388 C C   . PHE B 2 84  ? 119.531 117.684 122.609 1.00 47.36 ? 84  PHE B C   1 
ATOM   2389 O O   . PHE B 2 84  ? 120.144 116.839 123.269 1.00 53.74 ? 84  PHE B O   1 
ATOM   2390 C CB  . PHE B 2 84  ? 120.687 119.831 123.161 1.00 47.43 ? 84  PHE B CB  1 
ATOM   2391 C CG  . PHE B 2 84  ? 120.602 121.233 123.691 1.00 45.72 ? 84  PHE B CG  1 
ATOM   2392 C CD1 . PHE B 2 84  ? 119.674 122.122 123.179 1.00 55.53 ? 84  PHE B CD1 1 
ATOM   2393 C CD2 . PHE B 2 84  ? 121.472 121.675 124.672 1.00 45.69 ? 84  PHE B CD2 1 
ATOM   2394 C CE1 . PHE B 2 84  ? 119.594 123.407 123.652 1.00 57.43 ? 84  PHE B CE1 1 
ATOM   2395 C CE2 . PHE B 2 84  ? 121.389 122.961 125.154 1.00 55.19 ? 84  PHE B CE2 1 
ATOM   2396 C CZ  . PHE B 2 84  ? 120.449 123.830 124.635 1.00 57.64 ? 84  PHE B CZ  1 
ATOM   2397 N N   . ASP B 2 85  ? 119.009 117.444 121.406 1.00 51.90 ? 85  ASP B N   1 
ATOM   2398 C CA  . ASP B 2 85  ? 119.224 116.217 120.649 1.00 53.16 ? 85  ASP B CA  1 
ATOM   2399 C C   . ASP B 2 85  ? 119.745 116.570 119.264 1.00 61.92 ? 85  ASP B C   1 
ATOM   2400 O O   . ASP B 2 85  ? 119.128 117.369 118.553 1.00 67.13 ? 85  ASP B O   1 
ATOM   2401 C CB  . ASP B 2 85  ? 117.931 115.410 120.528 1.00 53.23 ? 85  ASP B CB  1 
ATOM   2402 C CG  . ASP B 2 85  ? 118.145 114.060 119.872 1.00 61.97 ? 85  ASP B CG  1 
ATOM   2403 O OD1 . ASP B 2 85  ? 119.301 113.590 119.815 1.00 62.91 ? 85  ASP B OD1 1 
ATOM   2404 O OD2 . ASP B 2 85  ? 117.151 113.480 119.386 1.00 62.43 ? 85  ASP B OD2 1 
ATOM   2405 N N   . VAL B 2 86  ? 120.855 115.947 118.875 1.00 59.72 ? 86  VAL B N   1 
ATOM   2406 C CA  . VAL B 2 86  ? 121.549 116.266 117.633 1.00 59.15 ? 86  VAL B CA  1 
ATOM   2407 C C   . VAL B 2 86  ? 121.214 115.114 116.686 1.00 58.54 ? 86  VAL B C   1 
ATOM   2408 O O   . VAL B 2 86  ? 121.731 114.004 116.837 1.00 59.03 ? 86  VAL B O   1 
ATOM   2409 C CB  . VAL B 2 86  ? 123.060 116.407 117.874 1.00 56.99 ? 86  VAL B CB  1 
ATOM   2410 C CG1 . VAL B 2 86  ? 123.875 116.654 116.580 1.00 57.56 ? 86  VAL B CG1 1 
ATOM   2411 C CG2 . VAL B 2 86  ? 123.343 117.465 118.950 1.00 52.12 ? 86  VAL B CG2 1 
ATOM   2412 N N   . GLY B 2 87  ? 120.353 115.375 115.702 1.00 60.88 ? 87  GLY B N   1 
ATOM   2413 C CA  . GLY B 2 87  ? 119.665 114.279 115.035 1.00 65.24 ? 87  GLY B CA  1 
ATOM   2414 C C   . GLY B 2 87  ? 120.504 113.541 114.005 1.00 68.32 ? 87  GLY B C   1 
ATOM   2415 O O   . GLY B 2 87  ? 120.615 112.313 114.049 1.00 70.60 ? 87  GLY B O   1 
ATOM   2416 N N   . GLY B 2 88  ? 121.111 114.274 113.070 1.00 69.52 ? 88  GLY B N   1 
ATOM   2417 C CA  . GLY B 2 88  ? 121.518 113.662 111.810 1.00 68.98 ? 88  GLY B CA  1 
ATOM   2418 C C   . GLY B 2 88  ? 122.785 112.824 111.886 1.00 69.63 ? 88  GLY B C   1 
ATOM   2419 O O   . GLY B 2 88  ? 123.099 112.082 110.951 1.00 65.74 ? 88  GLY B O   1 
ATOM   2420 N N   . GLN B 2 89  ? 123.526 112.924 112.990 1.00 69.96 ? 89  GLN B N   1 
ATOM   2421 C CA  . GLN B 2 89  ? 124.920 112.487 113.007 1.00 70.56 ? 89  GLN B CA  1 
ATOM   2422 C C   . GLN B 2 89  ? 125.049 110.968 113.070 1.00 71.23 ? 89  GLN B C   1 
ATOM   2423 O O   . GLN B 2 89  ? 124.117 110.258 113.459 1.00 68.81 ? 89  GLN B O   1 
ATOM   2424 C CB  . GLN B 2 89  ? 125.648 113.122 114.193 1.00 65.23 ? 89  GLN B CB  1 
ATOM   2425 C CG  . GLN B 2 89  ? 125.437 114.623 114.312 1.00 64.36 ? 89  GLN B CG  1 
ATOM   2426 C CD  . GLN B 2 89  ? 125.710 115.389 113.035 1.00 65.97 ? 89  GLN B CD  1 
ATOM   2427 O OE1 . GLN B 2 89  ? 126.506 114.964 112.203 1.00 64.36 ? 89  GLN B OE1 1 
ATOM   2428 N NE2 . GLN B 2 89  ? 125.036 116.521 112.865 1.00 64.50 ? 89  GLN B NE2 1 
ATOM   2429 N N   . ARG B 2 90  ? 126.227 110.476 112.681 1.00 74.74 ? 90  ARG B N   1 
ATOM   2430 C CA  . ARG B 2 90  ? 126.534 109.055 112.612 1.00 72.75 ? 90  ARG B CA  1 
ATOM   2431 C C   . ARG B 2 90  ? 127.039 108.538 113.965 1.00 76.60 ? 90  ARG B C   1 
ATOM   2432 O O   . ARG B 2 90  ? 126.877 109.182 115.005 1.00 71.66 ? 90  ARG B O   1 
ATOM   2433 C CB  . ARG B 2 90  ? 127.562 108.797 111.511 1.00 71.75 ? 90  ARG B CB  1 
ATOM   2434 N N   . ASP B 2 91  ? 127.648 107.343 113.942 1.00 78.72 ? 91  ASP B N   1 
ATOM   2435 C CA  . ASP B 2 91  ? 128.062 106.680 115.179 1.00 75.82 ? 91  ASP B CA  1 
ATOM   2436 C C   . ASP B 2 91  ? 129.113 107.483 115.940 1.00 70.98 ? 91  ASP B C   1 
ATOM   2437 O O   . ASP B 2 91  ? 129.012 107.642 117.162 1.00 68.63 ? 91  ASP B O   1 
ATOM   2438 C CB  . ASP B 2 91  ? 128.591 105.282 114.864 1.00 70.10 ? 91  ASP B CB  1 
ATOM   2439 N N   . GLU B 2 92  ? 130.131 107.991 115.246 1.00 72.04 ? 92  GLU B N   1 
ATOM   2440 C CA  . GLU B 2 92  ? 131.199 108.741 115.905 1.00 72.76 ? 92  GLU B CA  1 
ATOM   2441 C C   . GLU B 2 92  ? 130.692 110.150 116.186 1.00 72.34 ? 92  GLU B C   1 
ATOM   2442 O O   . GLU B 2 92  ? 130.469 110.933 115.256 1.00 72.14 ? 92  GLU B O   1 
ATOM   2443 C CB  . GLU B 2 92  ? 132.457 108.773 115.040 1.00 75.20 ? 92  GLU B CB  1 
ATOM   2444 C CG  . GLU B 2 92  ? 133.700 109.392 115.740 1.00 73.95 ? 92  GLU B CG  1 
ATOM   2445 C CD  . GLU B 2 92  ? 134.600 110.240 114.835 1.00 76.71 ? 92  GLU B CD  1 
ATOM   2446 O OE1 . GLU B 2 92  ? 134.228 110.557 113.685 1.00 71.88 ? 92  GLU B OE1 1 
ATOM   2447 O OE2 . GLU B 2 92  ? 135.704 110.599 115.294 1.00 75.53 ? 92  GLU B OE2 1 
ATOM   2448 N N   . ARG B 2 93  ? 130.518 110.470 117.468 1.00 60.43 ? 93  ARG B N   1 
ATOM   2449 C CA  . ARG B 2 93  ? 130.019 111.766 117.915 1.00 56.61 ? 93  ARG B CA  1 
ATOM   2450 C C   . ARG B 2 93  ? 131.112 112.635 118.529 1.00 53.40 ? 93  ARG B C   1 
ATOM   2451 O O   . ARG B 2 93  ? 130.801 113.674 119.114 1.00 51.72 ? 93  ARG B O   1 
ATOM   2452 C CB  . ARG B 2 93  ? 128.877 111.578 118.924 1.00 52.18 ? 93  ARG B CB  1 
ATOM   2453 C CG  . ARG B 2 93  ? 129.173 110.619 120.075 1.00 54.03 ? 93  ARG B CG  1 
ATOM   2454 C CD  . ARG B 2 93  ? 128.182 110.752 121.227 1.00 56.69 ? 93  ARG B CD  1 
ATOM   2455 N NE  . ARG B 2 93  ? 126.985 109.945 121.016 1.00 52.43 ? 93  ARG B NE  1 
ATOM   2456 C CZ  . ARG B 2 93  ? 126.887 108.644 121.260 1.00 54.25 ? 93  ARG B CZ  1 
ATOM   2457 N NH1 . ARG B 2 93  ? 127.921 107.930 121.680 1.00 52.59 ? 93  ARG B NH1 1 
ATOM   2458 N NH2 . ARG B 2 93  ? 125.719 108.037 121.069 1.00 58.49 ? 93  ARG B NH2 1 
ATOM   2459 N N   . ARG B 2 94  ? 132.384 112.249 118.384 1.00 62.94 ? 94  ARG B N   1 
ATOM   2460 C CA  . ARG B 2 94  ? 133.452 112.854 119.178 1.00 66.66 ? 94  ARG B CA  1 
ATOM   2461 C C   . ARG B 2 94  ? 133.641 114.334 118.857 1.00 64.10 ? 94  ARG B C   1 
ATOM   2462 O O   . ARG B 2 94  ? 134.090 115.104 119.713 1.00 64.13 ? 94  ARG B O   1 
ATOM   2463 C CB  . ARG B 2 94  ? 134.758 112.093 118.953 1.00 65.14 ? 94  ARG B CB  1 
ATOM   2464 N N   . LYS B 2 95  ? 133.328 114.746 117.626 1.00 47.23 ? 95  LYS B N   1 
ATOM   2465 C CA  . LYS B 2 95  ? 133.571 116.129 117.222 1.00 52.92 ? 95  LYS B CA  1 
ATOM   2466 C C   . LYS B 2 95  ? 132.457 117.067 117.671 1.00 53.95 ? 95  LYS B C   1 
ATOM   2467 O O   . LYS B 2 95  ? 132.726 118.207 118.068 1.00 50.56 ? 95  LYS B O   1 
ATOM   2468 C CB  . LYS B 2 95  ? 133.752 116.199 115.706 1.00 48.43 ? 95  LYS B CB  1 
ATOM   2469 C CG  . LYS B 2 95  ? 134.939 115.413 115.153 1.00 46.19 ? 95  LYS B CG  1 
ATOM   2470 C CD  . LYS B 2 95  ? 136.256 115.842 115.791 1.00 46.97 ? 95  LYS B CD  1 
ATOM   2471 C CE  . LYS B 2 95  ? 137.462 115.301 115.065 1.00 49.79 ? 95  LYS B CE  1 
ATOM   2472 N NZ  . LYS B 2 95  ? 138.705 115.792 115.718 1.00 46.34 ? 95  LYS B NZ  1 
ATOM   2473 N N   . TRP B 2 96  ? 131.201 116.635 117.572 1.00 53.78 ? 96  TRP B N   1 
ATOM   2474 C CA  . TRP B 2 96  ? 130.104 117.498 117.996 1.00 52.46 ? 96  TRP B CA  1 
ATOM   2475 C C   . TRP B 2 96  ? 129.888 117.432 119.505 1.00 57.76 ? 96  TRP B C   1 
ATOM   2476 O O   . TRP B 2 96  ? 129.328 118.363 120.095 1.00 59.31 ? 96  TRP B O   1 
ATOM   2477 C CB  . TRP B 2 96  ? 128.840 117.152 117.205 1.00 49.59 ? 96  TRP B CB  1 
ATOM   2478 C CG  . TRP B 2 96  ? 128.101 115.905 117.566 1.00 53.25 ? 96  TRP B CG  1 
ATOM   2479 C CD1 . TRP B 2 96  ? 128.097 114.742 116.861 1.00 52.95 ? 96  TRP B CD1 1 
ATOM   2480 C CD2 . TRP B 2 96  ? 127.184 115.716 118.652 1.00 54.67 ? 96  TRP B CD2 1 
ATOM   2481 N NE1 . TRP B 2 96  ? 127.266 113.829 117.454 1.00 58.41 ? 96  TRP B NE1 1 
ATOM   2482 C CE2 . TRP B 2 96  ? 126.695 114.401 118.558 1.00 55.75 ? 96  TRP B CE2 1 
ATOM   2483 C CE3 . TRP B 2 96  ? 126.744 116.522 119.704 1.00 53.83 ? 96  TRP B CE3 1 
ATOM   2484 C CZ2 . TRP B 2 96  ? 125.795 113.873 119.478 1.00 54.50 ? 96  TRP B CZ2 1 
ATOM   2485 C CZ3 . TRP B 2 96  ? 125.862 115.995 120.618 1.00 56.37 ? 96  TRP B CZ3 1 
ATOM   2486 C CH2 . TRP B 2 96  ? 125.389 114.686 120.496 1.00 53.67 ? 96  TRP B CH2 1 
ATOM   2487 N N   . ILE B 2 97  ? 130.327 116.348 120.153 1.00 59.12 ? 97  ILE B N   1 
ATOM   2488 C CA  . ILE B 2 97  ? 130.174 116.240 121.603 1.00 51.48 ? 97  ILE B CA  1 
ATOM   2489 C C   . ILE B 2 97  ? 131.115 117.202 122.330 1.00 49.24 ? 97  ILE B C   1 
ATOM   2490 O O   . ILE B 2 97  ? 130.926 117.487 123.518 1.00 52.94 ? 97  ILE B O   1 
ATOM   2491 C CB  . ILE B 2 97  ? 130.377 114.779 122.057 1.00 54.25 ? 97  ILE B CB  1 
ATOM   2492 C CG1 . ILE B 2 97  ? 129.661 114.502 123.380 1.00 54.90 ? 97  ILE B CG1 1 
ATOM   2493 C CG2 . ILE B 2 97  ? 131.850 114.424 122.178 1.00 56.59 ? 97  ILE B CG2 1 
ATOM   2494 C CD1 . ILE B 2 97  ? 128.159 114.340 123.260 1.00 56.01 ? 97  ILE B CD1 1 
ATOM   2495 N N   . GLN B 2 98  ? 132.149 117.707 121.642 1.00 46.64 ? 98  GLN B N   1 
ATOM   2496 C CA  . GLN B 2 98  ? 133.037 118.689 122.266 1.00 49.53 ? 98  GLN B CA  1 
ATOM   2497 C C   . GLN B 2 98  ? 132.284 119.965 122.624 1.00 55.76 ? 98  GLN B C   1 
ATOM   2498 O O   . GLN B 2 98  ? 132.646 120.659 123.581 1.00 53.83 ? 98  GLN B O   1 
ATOM   2499 C CB  . GLN B 2 98  ? 134.222 119.030 121.352 1.00 49.20 ? 98  GLN B CB  1 
ATOM   2500 C CG  . GLN B 2 98  ? 134.867 117.869 120.593 1.00 53.89 ? 98  GLN B CG  1 
ATOM   2501 C CD  . GLN B 2 98  ? 136.249 118.206 120.069 1.00 61.65 ? 98  GLN B CD  1 
ATOM   2502 O OE1 . GLN B 2 98  ? 136.643 119.371 120.025 1.00 59.58 ? 98  GLN B OE1 1 
ATOM   2503 N NE2 . GLN B 2 98  ? 136.994 117.183 119.665 1.00 52.40 ? 98  GLN B NE2 1 
ATOM   2504 N N   . CYS B 2 99  ? 131.245 120.299 121.855 1.00 56.64 ? 99  CYS B N   1 
ATOM   2505 C CA  . CYS B 2 99  ? 130.474 121.506 122.125 1.00 49.63 ? 99  CYS B CA  1 
ATOM   2506 C C   . CYS B 2 99  ? 129.770 121.429 123.474 1.00 50.08 ? 99  CYS B C   1 
ATOM   2507 O O   . CYS B 2 99  ? 129.742 122.412 124.224 1.00 51.37 ? 99  CYS B O   1 
ATOM   2508 C CB  . CYS B 2 99  ? 129.459 121.727 121.005 1.00 48.54 ? 99  CYS B CB  1 
ATOM   2509 S SG  . CYS B 2 99  ? 130.203 122.055 119.391 1.00 52.42 ? 99  CYS B SG  1 
ATOM   2510 N N   . PHE B 2 100 ? 129.202 120.269 123.801 1.00 51.46 ? 100 PHE B N   1 
ATOM   2511 C CA  . PHE B 2 100 ? 128.374 120.102 124.998 1.00 48.61 ? 100 PHE B CA  1 
ATOM   2512 C C   . PHE B 2 100 ? 129.228 119.596 126.162 1.00 49.39 ? 100 PHE B C   1 
ATOM   2513 O O   . PHE B 2 100 ? 129.130 118.448 126.600 1.00 51.93 ? 100 PHE B O   1 
ATOM   2514 C CB  . PHE B 2 100 ? 127.206 119.157 124.729 1.00 50.57 ? 100 PHE B CB  1 
ATOM   2515 C CG  . PHE B 2 100 ? 126.365 119.516 123.528 1.00 47.61 ? 100 PHE B CG  1 
ATOM   2516 C CD1 . PHE B 2 100 ? 126.756 119.188 122.239 1.00 46.91 ? 100 PHE B CD1 1 
ATOM   2517 C CD2 . PHE B 2 100 ? 125.165 120.175 123.701 1.00 50.98 ? 100 PHE B CD2 1 
ATOM   2518 C CE1 . PHE B 2 100 ? 125.972 119.522 121.158 1.00 51.81 ? 100 PHE B CE1 1 
ATOM   2519 C CE2 . PHE B 2 100 ? 124.379 120.505 122.621 1.00 51.78 ? 100 PHE B CE2 1 
ATOM   2520 C CZ  . PHE B 2 100 ? 124.783 120.178 121.349 1.00 50.05 ? 100 PHE B CZ  1 
ATOM   2521 N N   . ASN B 2 101 ? 130.087 120.490 126.653 1.00 45.29 ? 101 ASN B N   1 
ATOM   2522 C CA  . ASN B 2 101 ? 130.882 120.253 127.856 1.00 50.56 ? 101 ASN B CA  1 
ATOM   2523 C C   . ASN B 2 101 ? 130.538 121.201 128.998 1.00 51.44 ? 101 ASN B C   1 
ATOM   2524 O O   . ASN B 2 101 ? 131.082 121.033 130.094 1.00 55.89 ? 101 ASN B O   1 
ATOM   2525 C CB  . ASN B 2 101 ? 132.376 120.397 127.568 1.00 50.36 ? 101 ASN B CB  1 
ATOM   2526 C CG  . ASN B 2 101 ? 132.697 121.660 126.826 1.00 56.91 ? 101 ASN B CG  1 
ATOM   2527 O OD1 . ASN B 2 101 ? 131.802 122.423 126.462 1.00 59.46 ? 101 ASN B OD1 1 
ATOM   2528 N ND2 . ASN B 2 101 ? 133.971 121.925 126.647 1.00 58.63 ? 101 ASN B ND2 1 
ATOM   2529 N N   . ASP B 2 102 ? 129.709 122.218 128.759 1.00 49.88 ? 102 ASP B N   1 
ATOM   2530 C CA  . ASP B 2 102 ? 129.227 123.118 129.801 1.00 48.55 ? 102 ASP B CA  1 
ATOM   2531 C C   . ASP B 2 102 ? 127.795 122.825 130.235 1.00 51.59 ? 102 ASP B C   1 
ATOM   2532 O O   . ASP B 2 102 ? 127.255 123.565 131.062 1.00 55.59 ? 102 ASP B O   1 
ATOM   2533 C CB  . ASP B 2 102 ? 129.350 124.581 129.342 1.00 52.75 ? 102 ASP B CB  1 
ATOM   2534 C CG  . ASP B 2 102 ? 128.629 124.870 128.024 1.00 59.52 ? 102 ASP B CG  1 
ATOM   2535 O OD1 . ASP B 2 102 ? 127.761 124.079 127.597 1.00 51.71 ? 102 ASP B OD1 1 
ATOM   2536 O OD2 . ASP B 2 102 ? 128.936 125.913 127.409 1.00 59.79 ? 102 ASP B OD2 1 
ATOM   2537 N N   . VAL B 2 103 ? 127.166 121.776 129.696 1.00 49.84 ? 103 VAL B N   1 
ATOM   2538 C CA  . VAL B 2 103 ? 125.802 121.453 130.088 1.00 47.14 ? 103 VAL B CA  1 
ATOM   2539 C C   . VAL B 2 103 ? 125.782 121.037 131.555 1.00 49.78 ? 103 VAL B C   1 
ATOM   2540 O O   . VAL B 2 103 ? 126.774 120.539 132.101 1.00 47.53 ? 103 VAL B O   1 
ATOM   2541 C CB  . VAL B 2 103 ? 125.205 120.347 129.198 1.00 40.77 ? 103 VAL B CB  1 
ATOM   2542 C CG1 . VAL B 2 103 ? 125.131 120.807 127.752 1.00 44.11 ? 103 VAL B CG1 1 
ATOM   2543 C CG2 . VAL B 2 103 ? 125.976 119.025 129.323 1.00 41.68 ? 103 VAL B CG2 1 
ATOM   2544 N N   . THR B 2 104 ? 124.641 121.269 132.209 1.00 47.78 ? 104 THR B N   1 
ATOM   2545 C CA  . THR B 2 104 ? 124.497 120.858 133.601 1.00 43.11 ? 104 THR B CA  1 
ATOM   2546 C C   . THR B 2 104 ? 124.565 119.343 133.736 1.00 40.22 ? 104 THR B C   1 
ATOM   2547 O O   . THR B 2 104 ? 125.245 118.822 134.629 1.00 33.11 ? 104 THR B O   1 
ATOM   2548 C CB  . THR B 2 104 ? 123.178 121.385 134.166 1.00 38.42 ? 104 THR B CB  1 
ATOM   2549 O OG1 . THR B 2 104 ? 123.177 122.816 134.121 1.00 43.53 ? 104 THR B OG1 1 
ATOM   2550 C CG2 . THR B 2 104 ? 122.986 120.929 135.602 1.00 41.12 ? 104 THR B CG2 1 
ATOM   2551 N N   . ALA B 2 105 ? 123.881 118.621 132.853 1.00 40.52 ? 105 ALA B N   1 
ATOM   2552 C CA  . ALA B 2 105 ? 123.813 117.172 132.932 1.00 38.41 ? 105 ALA B CA  1 
ATOM   2553 C C   . ALA B 2 105 ? 123.544 116.607 131.548 1.00 36.92 ? 105 ALA B C   1 
ATOM   2554 O O   . ALA B 2 105 ? 123.051 117.300 130.655 1.00 41.72 ? 105 ALA B O   1 
ATOM   2555 C CB  . ALA B 2 105 ? 122.726 116.716 133.911 1.00 38.05 ? 105 ALA B CB  1 
ATOM   2556 N N   . ILE B 2 106 ? 123.884 115.332 131.388 1.00 35.00 ? 106 ILE B N   1 
ATOM   2557 C CA  . ILE B 2 106 ? 123.562 114.544 130.204 1.00 33.81 ? 106 ILE B CA  1 
ATOM   2558 C C   . ILE B 2 106 ? 122.448 113.588 130.588 1.00 33.80 ? 106 ILE B C   1 
ATOM   2559 O O   . ILE B 2 106 ? 122.472 113.013 131.681 1.00 46.41 ? 106 ILE B O   1 
ATOM   2560 C CB  . ILE B 2 106 ? 124.784 113.769 129.682 1.00 34.24 ? 106 ILE B CB  1 
ATOM   2561 C CG1 . ILE B 2 106 ? 125.889 114.726 129.234 1.00 38.28 ? 106 ILE B CG1 1 
ATOM   2562 C CG2 . ILE B 2 106 ? 124.377 112.850 128.534 1.00 35.62 ? 106 ILE B CG2 1 
ATOM   2563 C CD1 . ILE B 2 106 ? 127.241 114.119 129.260 1.00 40.32 ? 106 ILE B CD1 1 
ATOM   2564 N N   . ILE B 2 107 ? 121.465 113.440 129.708 1.00 32.32 ? 107 ILE B N   1 
ATOM   2565 C CA  . ILE B 2 107 ? 120.360 112.508 129.895 1.00 30.45 ? 107 ILE B CA  1 
ATOM   2566 C C   . ILE B 2 107 ? 120.580 111.357 128.928 1.00 41.42 ? 107 ILE B C   1 
ATOM   2567 O O   . ILE B 2 107 ? 120.484 111.538 127.708 1.00 55.79 ? 107 ILE B O   1 
ATOM   2568 C CB  . ILE B 2 107 ? 118.993 113.178 129.670 1.00 34.17 ? 107 ILE B CB  1 
ATOM   2569 C CG1 . ILE B 2 107 ? 118.825 114.409 130.581 1.00 38.63 ? 107 ILE B CG1 1 
ATOM   2570 C CG2 . ILE B 2 107 ? 117.872 112.153 129.901 1.00 40.02 ? 107 ILE B CG2 1 
ATOM   2571 C CD1 . ILE B 2 107 ? 117.628 115.261 130.263 1.00 40.35 ? 107 ILE B CD1 1 
ATOM   2572 N N   . PHE B 2 108 ? 120.866 110.177 129.472 1.00 37.45 ? 108 PHE B N   1 
ATOM   2573 C CA  . PHE B 2 108 ? 121.167 108.984 128.693 1.00 34.65 ? 108 PHE B CA  1 
ATOM   2574 C C   . PHE B 2 108 ? 120.015 108.006 128.850 1.00 39.90 ? 108 PHE B C   1 
ATOM   2575 O O   . PHE B 2 108 ? 119.698 107.597 129.970 1.00 46.63 ? 108 PHE B O   1 
ATOM   2576 C CB  . PHE B 2 108 ? 122.481 108.354 129.157 1.00 36.54 ? 108 PHE B CB  1 
ATOM   2577 C CG  . PHE B 2 108 ? 123.108 107.444 128.145 1.00 42.81 ? 108 PHE B CG  1 
ATOM   2578 C CD1 . PHE B 2 108 ? 122.700 106.128 128.023 1.00 41.57 ? 108 PHE B CD1 1 
ATOM   2579 C CD2 . PHE B 2 108 ? 124.106 107.910 127.310 1.00 42.28 ? 108 PHE B CD2 1 
ATOM   2580 C CE1 . PHE B 2 108 ? 123.278 105.298 127.090 1.00 37.54 ? 108 PHE B CE1 1 
ATOM   2581 C CE2 . PHE B 2 108 ? 124.684 107.084 126.376 1.00 42.35 ? 108 PHE B CE2 1 
ATOM   2582 C CZ  . PHE B 2 108 ? 124.269 105.777 126.267 1.00 45.81 ? 108 PHE B CZ  1 
ATOM   2583 N N   . VAL B 2 109 ? 119.397 107.630 127.732 1.00 39.40 ? 109 VAL B N   1 
ATOM   2584 C CA  . VAL B 2 109 ? 118.196 106.801 127.716 1.00 37.66 ? 109 VAL B CA  1 
ATOM   2585 C C   . VAL B 2 109 ? 118.554 105.454 127.110 1.00 40.09 ? 109 VAL B C   1 
ATOM   2586 O O   . VAL B 2 109 ? 119.157 105.395 126.033 1.00 45.77 ? 109 VAL B O   1 
ATOM   2587 C CB  . VAL B 2 109 ? 117.054 107.465 126.925 1.00 41.30 ? 109 VAL B CB  1 
ATOM   2588 C CG1 . VAL B 2 109 ? 115.716 106.843 127.301 1.00 39.73 ? 109 VAL B CG1 1 
ATOM   2589 C CG2 . VAL B 2 109 ? 117.040 108.966 127.160 1.00 43.69 ? 109 VAL B CG2 1 
ATOM   2590 N N   . VAL B 2 110 ? 118.184 104.380 127.806 1.00 46.90 ? 110 VAL B N   1 
ATOM   2591 C CA  . VAL B 2 110 ? 118.457 103.013 127.383 1.00 49.75 ? 110 VAL B CA  1 
ATOM   2592 C C   . VAL B 2 110 ? 117.165 102.214 127.461 1.00 51.25 ? 110 VAL B C   1 
ATOM   2593 O O   . VAL B 2 110 ? 116.328 102.437 128.341 1.00 52.28 ? 110 VAL B O   1 
ATOM   2594 C CB  . VAL B 2 110 ? 119.557 102.349 128.245 1.00 45.36 ? 110 VAL B CB  1 
ATOM   2595 C CG1 . VAL B 2 110 ? 119.900 100.966 127.695 1.00 49.88 ? 110 VAL B CG1 1 
ATOM   2596 C CG2 . VAL B 2 110 ? 120.795 103.239 128.313 1.00 44.44 ? 110 VAL B CG2 1 
ATOM   2597 N N   . ASP B 2 111 ? 117.006 101.282 126.525 1.00 53.20 ? 111 ASP B N   1 
ATOM   2598 C CA  . ASP B 2 111 ? 115.881 100.357 126.514 1.00 56.21 ? 111 ASP B CA  1 
ATOM   2599 C C   . ASP B 2 111 ? 116.281 99.101  127.277 1.00 61.78 ? 111 ASP B C   1 
ATOM   2600 O O   . ASP B 2 111 ? 117.007 98.253  126.748 1.00 64.34 ? 111 ASP B O   1 
ATOM   2601 C CB  . ASP B 2 111 ? 115.470 100.010 125.084 1.00 56.96 ? 111 ASP B CB  1 
ATOM   2602 N N   . SER B 2 112 ? 115.807 98.988  128.518 1.00 63.04 ? 112 SER B N   1 
ATOM   2603 C CA  . SER B 2 112 ? 116.129 97.820  129.331 1.00 59.62 ? 112 SER B CA  1 
ATOM   2604 C C   . SER B 2 112 ? 115.409 96.572  128.829 1.00 62.45 ? 112 SER B C   1 
ATOM   2605 O O   . SER B 2 112 ? 115.815 95.448  129.144 1.00 63.45 ? 112 SER B O   1 
ATOM   2606 C CB  . SER B 2 112 ? 115.775 98.093  130.791 1.00 62.32 ? 112 SER B CB  1 
ATOM   2607 O OG  . SER B 2 112 ? 114.513 98.727  130.896 1.00 67.69 ? 112 SER B OG  1 
ATOM   2608 N N   . SER B 2 113 ? 114.327 96.747  128.063 1.00 67.51 ? 113 SER B N   1 
ATOM   2609 C CA  . SER B 2 113 ? 113.560 95.601  127.583 1.00 70.18 ? 113 SER B CA  1 
ATOM   2610 C C   . SER B 2 113 ? 114.378 94.727  126.638 1.00 70.11 ? 113 SER B C   1 
ATOM   2611 O O   . SER B 2 113 ? 114.313 93.494  126.714 1.00 68.29 ? 113 SER B O   1 
ATOM   2612 C CB  . SER B 2 113 ? 112.287 96.083  126.889 1.00 71.18 ? 113 SER B CB  1 
ATOM   2613 O OG  . SER B 2 113 ? 112.512 97.303  126.206 1.00 70.05 ? 113 SER B OG  1 
ATOM   2614 N N   . ASP B 2 114 ? 115.153 95.340  125.747 1.00 71.62 ? 114 ASP B N   1 
ATOM   2615 C CA  . ASP B 2 114 ? 115.856 94.623  124.689 1.00 70.53 ? 114 ASP B CA  1 
ATOM   2616 C C   . ASP B 2 114 ? 117.255 94.267  125.179 1.00 73.24 ? 114 ASP B C   1 
ATOM   2617 O O   . ASP B 2 114 ? 118.026 95.153  125.564 1.00 73.08 ? 114 ASP B O   1 
ATOM   2618 C CB  . ASP B 2 114 ? 115.926 95.468  123.418 1.00 71.02 ? 114 ASP B CB  1 
ATOM   2619 C CG  . ASP B 2 114 ? 116.289 94.652  122.186 1.00 74.27 ? 114 ASP B CG  1 
ATOM   2620 O OD1 . ASP B 2 114 ? 117.076 93.689  122.296 1.00 74.48 ? 114 ASP B OD1 1 
ATOM   2621 O OD2 . ASP B 2 114 ? 115.778 94.979  121.095 1.00 74.93 ? 114 ASP B OD2 1 
ATOM   2622 N N   . TYR B 2 115 ? 117.579 92.970  125.147 1.00 75.16 ? 115 TYR B N   1 
ATOM   2623 C CA  . TYR B 2 115 ? 118.854 92.506  125.686 1.00 72.20 ? 115 TYR B CA  1 
ATOM   2624 C C   . TYR B 2 115 ? 119.947 92.514  124.624 1.00 73.34 ? 115 TYR B C   1 
ATOM   2625 O O   . TYR B 2 115 ? 121.128 92.696  124.942 1.00 73.91 ? 115 TYR B O   1 
ATOM   2626 C CB  . TYR B 2 115 ? 118.689 91.110  126.274 1.00 70.29 ? 115 TYR B CB  1 
ATOM   2627 C CG  . TYR B 2 115 ? 117.451 90.965  127.120 1.00 71.64 ? 115 TYR B CG  1 
ATOM   2628 C CD1 . TYR B 2 115 ? 117.308 91.672  128.303 1.00 72.16 ? 115 TYR B CD1 1 
ATOM   2629 C CD2 . TYR B 2 115 ? 116.429 90.109  126.743 1.00 73.19 ? 115 TYR B CD2 1 
ATOM   2630 C CE1 . TYR B 2 115 ? 116.174 91.546  129.075 1.00 73.33 ? 115 TYR B CE1 1 
ATOM   2631 C CE2 . TYR B 2 115 ? 115.297 89.969  127.513 1.00 72.05 ? 115 TYR B CE2 1 
ATOM   2632 C CZ  . TYR B 2 115 ? 115.174 90.687  128.680 1.00 72.49 ? 115 TYR B CZ  1 
ATOM   2633 O OH  . TYR B 2 115 ? 114.043 90.549  129.449 1.00 70.69 ? 115 TYR B OH  1 
ATOM   2634 N N   . ASN B 2 116 ? 119.578 92.301  123.359 1.00 71.24 ? 116 ASN B N   1 
ATOM   2635 C CA  . ASN B 2 116 ? 120.553 92.431  122.281 1.00 72.75 ? 116 ASN B CA  1 
ATOM   2636 C C   . ASN B 2 116 ? 121.083 93.855  122.204 1.00 72.58 ? 116 ASN B C   1 
ATOM   2637 O O   . ASN B 2 116 ? 122.261 94.077  121.901 1.00 72.44 ? 116 ASN B O   1 
ATOM   2638 C CB  . ASN B 2 116 ? 119.921 92.020  120.945 1.00 72.31 ? 116 ASN B CB  1 
ATOM   2639 C CG  . ASN B 2 116 ? 120.908 91.351  119.990 1.00 73.24 ? 116 ASN B CG  1 
ATOM   2640 O OD1 . ASN B 2 116 ? 121.897 90.741  120.400 1.00 72.06 ? 116 ASN B OD1 1 
ATOM   2641 N ND2 . ASN B 2 116 ? 120.631 91.470  118.698 1.00 73.70 ? 116 ASN B ND2 1 
ATOM   2642 N N   . ARG B 2 117 ? 120.220 94.835  122.472 1.00 69.71 ? 117 ARG B N   1 
ATOM   2643 C CA  . ARG B 2 117 ? 120.652 96.227  122.481 1.00 70.87 ? 117 ARG B CA  1 
ATOM   2644 C C   . ARG B 2 117 ? 121.496 96.552  123.711 1.00 69.43 ? 117 ARG B C   1 
ATOM   2645 O O   . ARG B 2 117 ? 122.239 97.537  123.705 1.00 67.58 ? 117 ARG B O   1 
ATOM   2646 C CB  . ARG B 2 117 ? 119.439 97.163  122.421 1.00 70.59 ? 117 ARG B CB  1 
ATOM   2647 C CG  . ARG B 2 117 ? 118.465 96.945  121.246 1.00 71.01 ? 117 ARG B CG  1 
ATOM   2648 C CD  . ARG B 2 117 ? 118.810 97.785  120.021 1.00 71.65 ? 117 ARG B CD  1 
ATOM   2649 N NE  . ARG B 2 117 ? 119.992 97.270  119.331 1.00 73.88 ? 117 ARG B NE  1 
ATOM   2650 C CZ  . ARG B 2 117 ? 120.962 97.992  118.777 1.00 72.27 ? 117 ARG B CZ  1 
ATOM   2651 N NH1 . ARG B 2 117 ? 120.928 99.318  118.746 1.00 68.27 ? 117 ARG B NH1 1 
ATOM   2652 N NH2 . ARG B 2 117 ? 121.995 97.365  118.223 1.00 71.20 ? 117 ARG B NH2 1 
ATOM   2653 N N   . LEU B 2 118 ? 121.380 95.756  124.783 1.00 61.79 ? 118 LEU B N   1 
ATOM   2654 C CA  . LEU B 2 118 ? 121.887 96.194  126.085 1.00 63.85 ? 118 LEU B CA  1 
ATOM   2655 C C   . LEU B 2 118 ? 123.408 96.304  126.115 1.00 64.63 ? 118 LEU B C   1 
ATOM   2656 O O   . LEU B 2 118 ? 123.949 97.233  126.723 1.00 66.52 ? 118 LEU B O   1 
ATOM   2657 C CB  . LEU B 2 118 ? 121.406 95.267  127.208 1.00 63.70 ? 118 LEU B CB  1 
ATOM   2658 C CG  . LEU B 2 118 ? 120.299 95.838  128.106 1.00 62.52 ? 118 LEU B CG  1 
ATOM   2659 C CD1 . LEU B 2 118 ? 119.676 94.747  128.965 1.00 61.46 ? 118 LEU B CD1 1 
ATOM   2660 C CD2 . LEU B 2 118 ? 120.825 96.966  128.993 1.00 62.76 ? 118 LEU B CD2 1 
ATOM   2661 N N   . GLN B 2 119 ? 124.123 95.361  125.496 1.00 62.05 ? 119 GLN B N   1 
ATOM   2662 C CA  . GLN B 2 119 ? 125.582 95.446  125.503 1.00 62.91 ? 119 GLN B CA  1 
ATOM   2663 C C   . GLN B 2 119 ? 126.067 96.646  124.696 1.00 63.01 ? 119 GLN B C   1 
ATOM   2664 O O   . GLN B 2 119 ? 127.016 97.333  125.096 1.00 57.94 ? 119 GLN B O   1 
ATOM   2665 C CB  . GLN B 2 119 ? 126.192 94.147  124.964 1.00 63.49 ? 119 GLN B CB  1 
ATOM   2666 C CG  . GLN B 2 119 ? 127.714 93.936  125.180 1.00 66.00 ? 119 GLN B CG  1 
ATOM   2667 C CD  . GLN B 2 119 ? 128.224 94.293  126.572 1.00 64.55 ? 119 GLN B CD  1 
ATOM   2668 O OE1 . GLN B 2 119 ? 127.662 93.864  127.580 1.00 61.53 ? 119 GLN B OE1 1 
ATOM   2669 N NE2 . GLN B 2 119 ? 129.300 95.072  126.629 1.00 60.58 ? 119 GLN B NE2 1 
ATOM   2670 N N   . GLU B 2 120 ? 125.424 96.916  123.558 1.00 64.07 ? 120 GLU B N   1 
ATOM   2671 C CA  . GLU B 2 120 ? 125.757 98.109  122.787 1.00 58.93 ? 120 GLU B CA  1 
ATOM   2672 C C   . GLU B 2 120 ? 125.448 99.374  123.577 1.00 63.61 ? 120 GLU B C   1 
ATOM   2673 O O   . GLU B 2 120 ? 126.197 100.355 123.513 1.00 64.02 ? 120 GLU B O   1 
ATOM   2674 C CB  . GLU B 2 120 ? 124.993 98.105  121.463 1.00 54.09 ? 120 GLU B CB  1 
ATOM   2675 N N   . ALA B 2 121 ? 124.342 99.370  124.325 1.00 59.89 ? 121 ALA B N   1 
ATOM   2676 C CA  . ALA B 2 121 ? 124.008 100.510 125.170 1.00 54.10 ? 121 ALA B CA  1 
ATOM   2677 C C   . ALA B 2 121 ? 125.048 100.707 126.262 1.00 52.27 ? 121 ALA B C   1 
ATOM   2678 O O   . ALA B 2 121 ? 125.397 101.841 126.597 1.00 54.29 ? 121 ALA B O   1 
ATOM   2679 C CB  . ALA B 2 121 ? 122.621 100.320 125.780 1.00 50.09 ? 121 ALA B CB  1 
ATOM   2680 N N   . LEU B 2 122 ? 125.546 99.612  126.837 1.00 50.83 ? 122 LEU B N   1 
ATOM   2681 C CA  . LEU B 2 122 ? 126.592 99.719  127.849 1.00 54.67 ? 122 LEU B CA  1 
ATOM   2682 C C   . LEU B 2 122 ? 127.875 100.275 127.247 1.00 58.04 ? 122 LEU B C   1 
ATOM   2683 O O   . LEU B 2 122 ? 128.557 101.102 127.866 1.00 58.20 ? 122 LEU B O   1 
ATOM   2684 C CB  . LEU B 2 122 ? 126.848 98.352  128.485 1.00 53.52 ? 122 LEU B CB  1 
ATOM   2685 C CG  . LEU B 2 122 ? 125.830 97.907  129.537 1.00 52.39 ? 122 LEU B CG  1 
ATOM   2686 C CD1 . LEU B 2 122 ? 125.764 96.394  129.613 1.00 53.83 ? 122 LEU B CD1 1 
ATOM   2687 C CD2 . LEU B 2 122 ? 126.148 98.491  130.897 1.00 58.07 ? 122 LEU B CD2 1 
ATOM   2688 N N   . ASN B 2 123 ? 128.218 99.834  126.034 1.00 61.47 ? 123 ASN B N   1 
ATOM   2689 C CA  . ASN B 2 123 ? 129.395 100.367 125.355 1.00 61.07 ? 123 ASN B CA  1 
ATOM   2690 C C   . ASN B 2 123 ? 129.237 101.857 125.078 1.00 60.19 ? 123 ASN B C   1 
ATOM   2691 O O   . ASN B 2 123 ? 130.177 102.639 125.264 1.00 59.37 ? 123 ASN B O   1 
ATOM   2692 C CB  . ASN B 2 123 ? 129.633 99.610  124.047 1.00 58.96 ? 123 ASN B CB  1 
ATOM   2693 C CG  . ASN B 2 123 ? 129.913 98.129  124.257 1.00 60.02 ? 123 ASN B CG  1 
ATOM   2694 O OD1 . ASN B 2 123 ? 129.329 97.283  123.580 1.00 56.72 ? 123 ASN B OD1 1 
ATOM   2695 N ND2 . ASN B 2 123 ? 130.825 97.809  125.170 1.00 60.56 ? 123 ASN B ND2 1 
ATOM   2696 N N   . ASP B 2 124 ? 128.048 102.268 124.636 1.00 54.72 ? 124 ASP B N   1 
ATOM   2697 C CA  . ASP B 2 124 ? 127.809 103.679 124.360 1.00 52.41 ? 124 ASP B CA  1 
ATOM   2698 C C   . ASP B 2 124 ? 127.834 104.505 125.641 1.00 52.21 ? 124 ASP B C   1 
ATOM   2699 O O   . ASP B 2 124 ? 128.321 105.642 125.646 1.00 52.88 ? 124 ASP B O   1 
ATOM   2700 C CB  . ASP B 2 124 ? 126.476 103.844 123.634 1.00 51.51 ? 124 ASP B CB  1 
ATOM   2701 C CG  . ASP B 2 124 ? 126.471 105.026 122.699 1.00 56.76 ? 124 ASP B CG  1 
ATOM   2702 O OD1 . ASP B 2 124 ? 126.426 106.173 123.189 1.00 54.00 ? 124 ASP B OD1 1 
ATOM   2703 O OD2 . ASP B 2 124 ? 126.521 104.813 121.470 1.00 60.08 ? 124 ASP B OD2 1 
ATOM   2704 N N   . PHE B 2 125 ? 127.308 103.955 126.738 1.00 47.35 ? 125 PHE B N   1 
ATOM   2705 C CA  . PHE B 2 125 ? 127.383 104.645 128.020 1.00 49.97 ? 125 PHE B CA  1 
ATOM   2706 C C   . PHE B 2 125 ? 128.828 104.805 128.465 1.00 54.22 ? 125 PHE B C   1 
ATOM   2707 O O   . PHE B 2 125 ? 129.202 105.846 129.012 1.00 52.08 ? 125 PHE B O   1 
ATOM   2708 C CB  . PHE B 2 125 ? 126.578 103.891 129.079 1.00 47.28 ? 125 PHE B CB  1 
ATOM   2709 C CG  . PHE B 2 125 ? 126.627 104.527 130.441 1.00 52.17 ? 125 PHE B CG  1 
ATOM   2710 C CD1 . PHE B 2 125 ? 125.820 105.611 130.743 1.00 54.01 ? 125 PHE B CD1 1 
ATOM   2711 C CD2 . PHE B 2 125 ? 127.474 104.040 131.420 1.00 48.42 ? 125 PHE B CD2 1 
ATOM   2712 C CE1 . PHE B 2 125 ? 125.863 106.199 131.991 1.00 46.99 ? 125 PHE B CE1 1 
ATOM   2713 C CE2 . PHE B 2 125 ? 127.519 104.624 132.669 1.00 51.80 ? 125 PHE B CE2 1 
ATOM   2714 C CZ  . PHE B 2 125 ? 126.712 105.704 132.954 1.00 50.52 ? 125 PHE B CZ  1 
ATOM   2715 N N   . LYS B 2 126 ? 129.654 103.781 128.243 1.00 57.95 ? 126 LYS B N   1 
ATOM   2716 C CA  . LYS B 2 126 ? 131.079 103.904 128.537 1.00 57.84 ? 126 LYS B CA  1 
ATOM   2717 C C   . LYS B 2 126 ? 131.725 104.985 127.677 1.00 55.53 ? 126 LYS B C   1 
ATOM   2718 O O   . LYS B 2 126 ? 132.577 105.746 128.155 1.00 58.37 ? 126 LYS B O   1 
ATOM   2719 C CB  . LYS B 2 126 ? 131.771 102.559 128.319 1.00 57.27 ? 126 LYS B CB  1 
ATOM   2720 C CG  . LYS B 2 126 ? 133.129 102.444 128.987 1.00 60.49 ? 126 LYS B CG  1 
ATOM   2721 C CD  . LYS B 2 126 ? 133.607 101.003 129.047 1.00 59.38 ? 126 LYS B CD  1 
ATOM   2722 C CE  . LYS B 2 126 ? 134.939 100.885 129.773 1.00 59.33 ? 126 LYS B CE  1 
ATOM   2723 N NZ  . LYS B 2 126 ? 134.850 101.266 131.209 1.00 60.31 ? 126 LYS B NZ  1 
ATOM   2724 N N   . SER B 2 127 ? 131.332 105.060 126.402 1.00 49.74 ? 127 SER B N   1 
ATOM   2725 C CA  . SER B 2 127 ? 131.869 106.088 125.513 1.00 52.78 ? 127 SER B CA  1 
ATOM   2726 C C   . SER B 2 127 ? 131.504 107.486 125.998 1.00 57.53 ? 127 SER B C   1 
ATOM   2727 O O   . SER B 2 127 ? 132.342 108.396 125.981 1.00 54.17 ? 127 SER B O   1 
ATOM   2728 C CB  . SER B 2 127 ? 131.356 105.876 124.089 1.00 54.60 ? 127 SER B CB  1 
ATOM   2729 O OG  . SER B 2 127 ? 131.220 107.113 123.414 1.00 54.99 ? 127 SER B OG  1 
ATOM   2730 N N   . ILE B 2 128 ? 130.253 107.677 126.422 1.00 58.59 ? 128 ILE B N   1 
ATOM   2731 C CA  . ILE B 2 128 ? 129.841 108.962 126.989 1.00 53.62 ? 128 ILE B CA  1 
ATOM   2732 C C   . ILE B 2 128 ? 130.616 109.243 128.270 1.00 55.33 ? 128 ILE B C   1 
ATOM   2733 O O   . ILE B 2 128 ? 131.063 110.371 128.510 1.00 57.19 ? 128 ILE B O   1 
ATOM   2734 C CB  . ILE B 2 128 ? 128.309 108.983 127.211 1.00 49.54 ? 128 ILE B CB  1 
ATOM   2735 C CG1 . ILE B 2 128 ? 127.598 109.586 125.995 1.00 52.40 ? 128 ILE B CG1 1 
ATOM   2736 C CG2 . ILE B 2 128 ? 127.878 109.782 128.470 1.00 53.49 ? 128 ILE B CG2 1 
ATOM   2737 C CD1 . ILE B 2 128 ? 127.840 108.863 124.695 1.00 56.70 ? 128 ILE B CD1 1 
ATOM   2738 N N   . TRP B 2 129 ? 130.776 108.225 129.117 1.00 49.54 ? 129 TRP B N   1 
ATOM   2739 C CA  . TRP B 2 129 ? 131.349 108.430 130.442 1.00 46.54 ? 129 TRP B CA  1 
ATOM   2740 C C   . TRP B 2 129 ? 132.819 108.817 130.365 1.00 46.03 ? 129 TRP B C   1 
ATOM   2741 O O   . TRP B 2 129 ? 133.273 109.698 131.103 1.00 50.43 ? 129 TRP B O   1 
ATOM   2742 C CB  . TRP B 2 129 ? 131.166 107.159 131.272 1.00 47.90 ? 129 TRP B CB  1 
ATOM   2743 C CG  . TRP B 2 129 ? 131.372 107.348 132.736 1.00 50.80 ? 129 TRP B CG  1 
ATOM   2744 C CD1 . TRP B 2 129 ? 132.409 106.878 133.485 1.00 54.26 ? 129 TRP B CD1 1 
ATOM   2745 C CD2 . TRP B 2 129 ? 130.514 108.055 133.638 1.00 48.60 ? 129 TRP B CD2 1 
ATOM   2746 N NE1 . TRP B 2 129 ? 132.252 107.250 134.797 1.00 51.93 ? 129 TRP B NE1 1 
ATOM   2747 C CE2 . TRP B 2 129 ? 131.095 107.973 134.917 1.00 50.83 ? 129 TRP B CE2 1 
ATOM   2748 C CE3 . TRP B 2 129 ? 129.312 108.751 133.488 1.00 50.32 ? 129 TRP B CE3 1 
ATOM   2749 C CZ2 . TRP B 2 129 ? 130.517 108.563 136.036 1.00 51.57 ? 129 TRP B CZ2 1 
ATOM   2750 C CZ3 . TRP B 2 129 ? 128.741 109.333 134.600 1.00 48.24 ? 129 TRP B CZ3 1 
ATOM   2751 C CH2 . TRP B 2 129 ? 129.342 109.236 135.857 1.00 46.23 ? 129 TRP B CH2 1 
ATOM   2752 N N   . ASN B 2 130 ? 133.576 108.179 129.473 1.00 55.48 ? 130 ASN B N   1 
ATOM   2753 C CA  . ASN B 2 130 ? 135.027 108.330 129.432 1.00 62.17 ? 130 ASN B CA  1 
ATOM   2754 C C   . ASN B 2 130 ? 135.514 109.395 128.454 1.00 64.64 ? 130 ASN B C   1 
ATOM   2755 O O   . ASN B 2 130 ? 136.728 109.526 128.268 1.00 63.61 ? 130 ASN B O   1 
ATOM   2756 C CB  . ASN B 2 130 ? 135.673 106.983 129.093 1.00 60.79 ? 130 ASN B CB  1 
ATOM   2757 C CG  . ASN B 2 130 ? 135.544 105.981 130.221 1.00 62.36 ? 130 ASN B CG  1 
ATOM   2758 O OD1 . ASN B 2 130 ? 136.193 106.112 131.258 1.00 58.26 ? 130 ASN B OD1 1 
ATOM   2759 N ND2 . ASN B 2 130 ? 134.694 104.983 130.032 1.00 61.64 ? 130 ASN B ND2 1 
ATOM   2760 N N   . ASN B 2 131 ? 134.618 110.155 127.825 1.00 62.00 ? 131 ASN B N   1 
ATOM   2761 C CA  . ASN B 2 131 ? 135.054 111.210 126.918 1.00 57.83 ? 131 ASN B CA  1 
ATOM   2762 C C   . ASN B 2 131 ? 135.803 112.290 127.690 1.00 56.87 ? 131 ASN B C   1 
ATOM   2763 O O   . ASN B 2 131 ? 135.454 112.615 128.827 1.00 61.11 ? 131 ASN B O   1 
ATOM   2764 C CB  . ASN B 2 131 ? 133.852 111.811 126.192 1.00 58.71 ? 131 ASN B CB  1 
ATOM   2765 C CG  . ASN B 2 131 ? 134.236 112.473 124.886 1.00 65.86 ? 131 ASN B CG  1 
ATOM   2766 O OD1 . ASN B 2 131 ? 134.932 113.487 124.874 1.00 64.89 ? 131 ASN B OD1 1 
ATOM   2767 N ND2 . ASN B 2 131 ? 133.792 111.896 123.775 1.00 64.62 ? 131 ASN B ND2 1 
ATOM   2768 N N   . ARG B 2 132 ? 136.851 112.839 127.067 1.00 55.69 ? 132 ARG B N   1 
ATOM   2769 C CA  . ARG B 2 132 ? 137.713 113.793 127.764 1.00 60.70 ? 132 ARG B CA  1 
ATOM   2770 C C   . ARG B 2 132 ? 136.962 115.074 128.100 1.00 61.75 ? 132 ARG B C   1 
ATOM   2771 O O   . ARG B 2 132 ? 137.117 115.626 129.196 1.00 61.78 ? 132 ARG B O   1 
ATOM   2772 C CB  . ARG B 2 132 ? 138.954 114.135 126.929 1.00 61.53 ? 132 ARG B CB  1 
ATOM   2773 C CG  . ARG B 2 132 ? 139.731 112.955 126.299 1.00 64.79 ? 132 ARG B CG  1 
ATOM   2774 C CD  . ARG B 2 132 ? 140.203 113.247 124.871 1.00 64.90 ? 132 ARG B CD  1 
ATOM   2775 N NE  . ARG B 2 132 ? 139.115 113.568 123.952 1.00 65.94 ? 132 ARG B NE  1 
ATOM   2776 C CZ  . ARG B 2 132 ? 138.275 112.689 123.418 1.00 66.20 ? 132 ARG B CZ  1 
ATOM   2777 N NH1 . ARG B 2 132 ? 138.352 111.394 123.686 1.00 64.02 ? 132 ARG B NH1 1 
ATOM   2778 N NH2 . ARG B 2 132 ? 137.327 113.123 122.592 1.00 65.98 ? 132 ARG B NH2 1 
ATOM   2779 N N   . TRP B 2 133 ? 136.149 115.565 127.166 1.00 56.26 ? 133 TRP B N   1 
ATOM   2780 C CA  . TRP B 2 133 ? 135.457 116.832 127.378 1.00 54.77 ? 133 TRP B CA  1 
ATOM   2781 C C   . TRP B 2 133 ? 134.301 116.669 128.355 1.00 58.75 ? 133 TRP B C   1 
ATOM   2782 O O   . TRP B 2 133 ? 133.967 117.602 129.094 1.00 58.77 ? 133 TRP B O   1 
ATOM   2783 C CB  . TRP B 2 133 ? 134.964 117.383 126.041 1.00 58.04 ? 133 TRP B CB  1 
ATOM   2784 C CG  . TRP B 2 133 ? 136.013 117.378 124.971 1.00 60.83 ? 133 TRP B CG  1 
ATOM   2785 C CD1 . TRP B 2 133 ? 135.933 116.762 123.765 1.00 57.86 ? 133 TRP B CD1 1 
ATOM   2786 C CD2 . TRP B 2 133 ? 137.293 118.022 125.009 1.00 59.49 ? 133 TRP B CD2 1 
ATOM   2787 N NE1 . TRP B 2 133 ? 137.081 116.974 123.043 1.00 60.13 ? 133 TRP B NE1 1 
ATOM   2788 C CE2 . TRP B 2 133 ? 137.933 117.746 123.786 1.00 55.15 ? 133 TRP B CE2 1 
ATOM   2789 C CE3 . TRP B 2 133 ? 137.960 118.802 125.957 1.00 57.82 ? 133 TRP B CE3 1 
ATOM   2790 C CZ2 . TRP B 2 133 ? 139.205 118.222 123.486 1.00 52.26 ? 133 TRP B CZ2 1 
ATOM   2791 C CZ3 . TRP B 2 133 ? 139.224 119.274 125.657 1.00 56.44 ? 133 TRP B CZ3 1 
ATOM   2792 C CH2 . TRP B 2 133 ? 139.833 118.982 124.432 1.00 57.64 ? 133 TRP B CH2 1 
ATOM   2793 N N   . LEU B 2 134 ? 133.681 115.490 128.375 1.00 56.79 ? 134 LEU B N   1 
ATOM   2794 C CA  . LEU B 2 134 ? 132.568 115.184 129.263 1.00 53.58 ? 134 LEU B CA  1 
ATOM   2795 C C   . LEU B 2 134 ? 133.030 114.629 130.607 1.00 50.97 ? 134 LEU B C   1 
ATOM   2796 O O   . LEU B 2 134 ? 132.269 113.909 131.261 1.00 50.62 ? 134 LEU B O   1 
ATOM   2797 C CB  . LEU B 2 134 ? 131.623 114.179 128.588 1.00 49.60 ? 134 LEU B CB  1 
ATOM   2798 C CG  . LEU B 2 134 ? 131.057 114.465 127.181 1.00 47.30 ? 134 LEU B CG  1 
ATOM   2799 C CD1 . LEU B 2 134 ? 129.668 113.872 126.978 1.00 54.52 ? 134 LEU B CD1 1 
ATOM   2800 C CD2 . LEU B 2 134 ? 130.997 115.956 126.851 1.00 46.80 ? 134 LEU B CD2 1 
ATOM   2801 N N   . ARG B 2 135 ? 134.263 114.929 131.022 1.00 56.55 ? 135 ARG B N   1 
ATOM   2802 C CA  . ARG B 2 135 ? 134.795 114.361 132.256 1.00 60.85 ? 135 ARG B CA  1 
ATOM   2803 C C   . ARG B 2 135 ? 134.078 114.902 133.486 1.00 61.44 ? 135 ARG B C   1 
ATOM   2804 O O   . ARG B 2 135 ? 133.870 114.170 134.457 1.00 62.93 ? 135 ARG B O   1 
ATOM   2805 C CB  . ARG B 2 135 ? 136.295 114.634 132.357 1.00 59.71 ? 135 ARG B CB  1 
ATOM   2806 C CG  . ARG B 2 135 ? 137.148 113.596 131.649 1.00 62.52 ? 135 ARG B CG  1 
ATOM   2807 C CD  . ARG B 2 135 ? 138.620 113.983 131.565 1.00 62.89 ? 135 ARG B CD  1 
ATOM   2808 N NE  . ARG B 2 135 ? 139.232 114.154 132.881 1.00 64.96 ? 135 ARG B NE  1 
ATOM   2809 C CZ  . ARG B 2 135 ? 139.279 115.282 133.583 1.00 62.52 ? 135 ARG B CZ  1 
ATOM   2810 N NH1 . ARG B 2 135 ? 138.782 116.420 133.120 1.00 60.91 ? 135 ARG B NH1 1 
ATOM   2811 N NH2 . ARG B 2 135 ? 139.842 115.270 134.787 1.00 59.56 ? 135 ARG B NH2 1 
ATOM   2812 N N   . THR B 2 136 ? 133.719 116.183 133.479 1.00 53.35 ? 136 THR B N   1 
ATOM   2813 C CA  . THR B 2 136 ? 133.125 116.836 134.641 1.00 51.93 ? 136 THR B CA  1 
ATOM   2814 C C   . THR B 2 136 ? 131.597 116.824 134.640 1.00 52.55 ? 136 THR B C   1 
ATOM   2815 O O   . THR B 2 136 ? 130.996 117.379 135.566 1.00 55.15 ? 136 THR B O   1 
ATOM   2816 C CB  . THR B 2 136 ? 133.621 118.285 134.730 1.00 54.64 ? 136 THR B CB  1 
ATOM   2817 O OG1 . THR B 2 136 ? 133.672 118.861 133.419 1.00 57.78 ? 136 THR B OG1 1 
ATOM   2818 C CG2 . THR B 2 136 ? 135.005 118.333 135.353 1.00 56.17 ? 136 THR B CG2 1 
ATOM   2819 N N   . ILE B 2 137 ? 130.955 116.193 133.658 1.00 47.84 ? 137 ILE B N   1 
ATOM   2820 C CA  . ILE B 2 137 ? 129.509 116.278 133.468 1.00 45.73 ? 137 ILE B CA  1 
ATOM   2821 C C   . ILE B 2 137 ? 128.868 115.007 134.002 1.00 46.61 ? 137 ILE B C   1 
ATOM   2822 O O   . ILE B 2 137 ? 129.227 113.898 133.589 1.00 56.02 ? 137 ILE B O   1 
ATOM   2823 C CB  . ILE B 2 137 ? 129.144 116.500 131.989 1.00 42.11 ? 137 ILE B CB  1 
ATOM   2824 C CG1 . ILE B 2 137 ? 130.093 117.489 131.289 1.00 46.42 ? 137 ILE B CG1 1 
ATOM   2825 C CG2 . ILE B 2 137 ? 127.714 117.006 131.864 1.00 45.16 ? 137 ILE B CG2 1 
ATOM   2826 C CD1 . ILE B 2 137 ? 130.225 118.879 131.929 1.00 52.41 ? 137 ILE B CD1 1 
ATOM   2827 N N   . SER B 2 138 ? 127.922 115.167 134.924 1.00 41.35 ? 138 SER B N   1 
ATOM   2828 C CA  . SER B 2 138 ? 127.162 114.036 135.432 1.00 43.61 ? 138 SER B CA  1 
ATOM   2829 C C   . SER B 2 138 ? 126.130 113.586 134.408 1.00 35.20 ? 138 SER B C   1 
ATOM   2830 O O   . SER B 2 138 ? 125.665 114.371 133.579 1.00 44.90 ? 138 SER B O   1 
ATOM   2831 C CB  . SER B 2 138 ? 126.468 114.402 136.742 1.00 42.33 ? 138 SER B CB  1 
ATOM   2832 O OG  . SER B 2 138 ? 127.402 114.519 137.800 1.00 42.76 ? 138 SER B OG  1 
ATOM   2833 N N   . VAL B 2 139 ? 125.770 112.306 134.480 1.00 32.49 ? 139 VAL B N   1 
ATOM   2834 C CA  . VAL B 2 139 ? 124.807 111.681 133.580 1.00 37.69 ? 139 VAL B CA  1 
ATOM   2835 C C   . VAL B 2 139 ? 123.584 111.288 134.393 1.00 38.31 ? 139 VAL B C   1 
ATOM   2836 O O   . VAL B 2 139 ? 123.718 110.697 135.468 1.00 46.73 ? 139 VAL B O   1 
ATOM   2837 C CB  . VAL B 2 139 ? 125.401 110.450 132.870 1.00 41.42 ? 139 VAL B CB  1 
ATOM   2838 C CG1 . VAL B 2 139 ? 124.357 109.799 131.966 1.00 37.81 ? 139 VAL B CG1 1 
ATOM   2839 C CG2 . VAL B 2 139 ? 126.645 110.834 132.074 1.00 43.69 ? 139 VAL B CG2 1 
ATOM   2840 N N   . ILE B 2 140 ? 122.402 111.628 133.892 1.00 39.15 ? 140 ILE B N   1 
ATOM   2841 C CA  . ILE B 2 140 ? 121.140 111.155 134.452 1.00 40.10 ? 140 ILE B CA  1 
ATOM   2842 C C   . ILE B 2 140 ? 120.661 110.027 133.551 1.00 38.89 ? 140 ILE B C   1 
ATOM   2843 O O   . ILE B 2 140 ? 120.195 110.272 132.433 1.00 50.95 ? 140 ILE B O   1 
ATOM   2844 C CB  . ILE B 2 140 ? 120.096 112.282 134.549 1.00 38.42 ? 140 ILE B CB  1 
ATOM   2845 C CG1 . ILE B 2 140 ? 120.564 113.405 135.483 1.00 38.54 ? 140 ILE B CG1 1 
ATOM   2846 C CG2 . ILE B 2 140 ? 118.782 111.744 135.090 1.00 41.12 ? 140 ILE B CG2 1 
ATOM   2847 C CD1 . ILE B 2 140 ? 119.966 114.750 135.157 1.00 39.18 ? 140 ILE B CD1 1 
ATOM   2848 N N   . LEU B 2 141 ? 120.759 108.794 134.036 1.00 31.93 ? 141 LEU B N   1 
ATOM   2849 C CA  . LEU B 2 141 ? 120.508 107.606 133.233 1.00 36.95 ? 141 LEU B CA  1 
ATOM   2850 C C   . LEU B 2 141 ? 119.080 107.140 133.468 1.00 35.72 ? 141 LEU B C   1 
ATOM   2851 O O   . LEU B 2 141 ? 118.716 106.798 134.597 1.00 43.04 ? 141 LEU B O   1 
ATOM   2852 C CB  . LEU B 2 141 ? 121.507 106.499 133.589 1.00 45.81 ? 141 LEU B CB  1 
ATOM   2853 C CG  . LEU B 2 141 ? 121.388 105.108 132.955 1.00 40.39 ? 141 LEU B CG  1 
ATOM   2854 C CD1 . LEU B 2 141 ? 121.844 105.124 131.511 1.00 40.50 ? 141 LEU B CD1 1 
ATOM   2855 C CD2 . LEU B 2 141 ? 122.203 104.110 133.750 1.00 37.72 ? 141 LEU B CD2 1 
ATOM   2856 N N   . PHE B 2 142 ? 118.280 107.125 132.402 1.00 37.70 ? 142 PHE B N   1 
ATOM   2857 C CA  . PHE B 2 142 ? 116.914 106.617 132.432 1.00 42.58 ? 142 PHE B CA  1 
ATOM   2858 C C   . PHE B 2 142 ? 116.885 105.258 131.753 1.00 39.79 ? 142 PHE B C   1 
ATOM   2859 O O   . PHE B 2 142 ? 117.130 105.159 130.547 1.00 49.72 ? 142 PHE B O   1 
ATOM   2860 C CB  . PHE B 2 142 ? 115.933 107.554 131.729 1.00 44.00 ? 142 PHE B CB  1 
ATOM   2861 C CG  . PHE B 2 142 ? 115.630 108.812 132.486 1.00 43.16 ? 142 PHE B CG  1 
ATOM   2862 C CD1 . PHE B 2 142 ? 114.742 108.804 133.543 1.00 45.25 ? 142 PHE B CD1 1 
ATOM   2863 C CD2 . PHE B 2 142 ? 116.247 109.997 132.153 1.00 43.50 ? 142 PHE B CD2 1 
ATOM   2864 C CE1 . PHE B 2 142 ? 114.464 109.952 134.238 1.00 46.66 ? 142 PHE B CE1 1 
ATOM   2865 C CE2 . PHE B 2 142 ? 115.963 111.152 132.841 1.00 41.64 ? 142 PHE B CE2 1 
ATOM   2866 C CZ  . PHE B 2 142 ? 115.076 111.124 133.890 1.00 46.66 ? 142 PHE B CZ  1 
ATOM   2867 N N   . LEU B 2 143 ? 116.593 104.220 132.528 1.00 44.14 ? 143 LEU B N   1 
ATOM   2868 C CA  . LEU B 2 143 ? 116.323 102.907 131.964 1.00 50.67 ? 143 LEU B CA  1 
ATOM   2869 C C   . LEU B 2 143 ? 114.843 102.809 131.610 1.00 49.13 ? 143 LEU B C   1 
ATOM   2870 O O   . LEU B 2 143 ? 113.973 103.028 132.456 1.00 49.66 ? 143 LEU B O   1 
ATOM   2871 C CB  . LEU B 2 143 ? 116.732 101.816 132.954 1.00 51.64 ? 143 LEU B CB  1 
ATOM   2872 C CG  . LEU B 2 143 ? 118.139 101.948 133.561 1.00 45.70 ? 143 LEU B CG  1 
ATOM   2873 C CD1 . LEU B 2 143 ? 118.335 100.949 134.670 1.00 50.42 ? 143 LEU B CD1 1 
ATOM   2874 C CD2 . LEU B 2 143 ? 119.204 101.768 132.493 1.00 51.99 ? 143 LEU B CD2 1 
ATOM   2875 N N   . ASN B 2 144 ? 114.563 102.459 130.355 1.00 50.90 ? 144 ASN B N   1 
ATOM   2876 C CA  . ASN B 2 144 ? 113.281 102.743 129.727 1.00 53.19 ? 144 ASN B CA  1 
ATOM   2877 C C   . ASN B 2 144 ? 112.519 101.459 129.427 1.00 53.52 ? 144 ASN B C   1 
ATOM   2878 O O   . ASN B 2 144 ? 113.090 100.368 129.360 1.00 54.34 ? 144 ASN B O   1 
ATOM   2879 C CB  . ASN B 2 144 ? 113.476 103.538 128.428 1.00 52.14 ? 144 ASN B CB  1 
ATOM   2880 C CG  . ASN B 2 144 ? 112.292 104.426 128.097 1.00 52.46 ? 144 ASN B CG  1 
ATOM   2881 O OD1 . ASN B 2 144 ? 111.189 104.228 128.601 1.00 55.42 ? 144 ASN B OD1 1 
ATOM   2882 N ND2 . ASN B 2 144 ? 112.519 105.412 127.240 1.00 51.04 ? 144 ASN B ND2 1 
ATOM   2883 N N   . LYS B 2 145 ? 111.207 101.622 129.234 1.00 58.98 ? 145 LYS B N   1 
ATOM   2884 C CA  . LYS B 2 145 ? 110.293 100.535 128.871 1.00 59.16 ? 145 LYS B CA  1 
ATOM   2885 C C   . LYS B 2 145 ? 110.330 99.413  129.912 1.00 61.39 ? 145 LYS B C   1 
ATOM   2886 O O   . LYS B 2 145 ? 110.399 98.219  129.590 1.00 63.66 ? 145 LYS B O   1 
ATOM   2887 C CB  . LYS B 2 145 ? 110.593 100.022 127.458 1.00 59.43 ? 145 LYS B CB  1 
ATOM   2888 C CG  . LYS B 2 145 ? 110.276 101.072 126.393 1.00 60.09 ? 145 LYS B CG  1 
ATOM   2889 C CD  . LYS B 2 145 ? 110.588 100.598 124.973 1.00 63.10 ? 145 LYS B CD  1 
ATOM   2890 C CE  . LYS B 2 145 ? 110.246 101.644 123.905 1.00 59.86 ? 145 LYS B CE  1 
ATOM   2891 N NZ  . LYS B 2 145 ? 110.554 101.239 122.500 1.00 57.66 ? 145 LYS B NZ  1 
ATOM   2892 N N   . GLN B 2 146 ? 110.271 99.812  131.185 1.00 58.48 ? 146 GLN B N   1 
ATOM   2893 C CA  . GLN B 2 146 ? 110.257 98.836  132.267 1.00 58.55 ? 146 GLN B CA  1 
ATOM   2894 C C   . GLN B 2 146 ? 109.006 97.968  132.214 1.00 59.24 ? 146 GLN B C   1 
ATOM   2895 O O   . GLN B 2 146 ? 109.029 96.820  132.662 1.00 62.06 ? 146 GLN B O   1 
ATOM   2896 C CB  . GLN B 2 146 ? 110.388 99.545  133.619 1.00 60.07 ? 146 GLN B CB  1 
ATOM   2897 C CG  . GLN B 2 146 ? 109.191 100.397 134.058 1.00 62.60 ? 146 GLN B CG  1 
ATOM   2898 C CD  . GLN B 2 146 ? 109.354 100.950 135.458 1.00 63.03 ? 146 GLN B CD  1 
ATOM   2899 O OE1 . GLN B 2 146 ? 110.006 100.342 136.307 1.00 63.24 ? 146 GLN B OE1 1 
ATOM   2900 N NE2 . GLN B 2 146 ? 108.761 102.110 135.708 1.00 59.79 ? 146 GLN B NE2 1 
ATOM   2901 N N   . ASP B 2 147 ? 107.900 98.495  131.681 1.00 61.14 ? 147 ASP B N   1 
ATOM   2902 C CA  . ASP B 2 147 ? 106.714 97.662  131.499 1.00 64.86 ? 147 ASP B CA  1 
ATOM   2903 C C   . ASP B 2 147 ? 106.981 96.549  130.491 1.00 67.85 ? 147 ASP B C   1 
ATOM   2904 O O   . ASP B 2 147 ? 106.572 95.398  130.701 1.00 67.00 ? 147 ASP B O   1 
ATOM   2905 C CB  . ASP B 2 147 ? 105.529 98.522  131.057 1.00 65.39 ? 147 ASP B CB  1 
ATOM   2906 C CG  . ASP B 2 147 ? 104.218 97.747  131.018 1.00 69.07 ? 147 ASP B CG  1 
ATOM   2907 O OD1 . ASP B 2 147 ? 104.069 96.833  130.178 1.00 68.11 ? 147 ASP B OD1 1 
ATOM   2908 O OD2 . ASP B 2 147 ? 103.318 98.073  131.820 1.00 68.27 ? 147 ASP B OD2 1 
ATOM   2909 N N   . LEU B 2 148 ? 107.657 96.880  129.386 1.00 68.95 ? 148 LEU B N   1 
ATOM   2910 C CA  . LEU B 2 148 ? 108.028 95.864  128.406 1.00 67.16 ? 148 LEU B CA  1 
ATOM   2911 C C   . LEU B 2 148 ? 108.935 94.816  129.034 1.00 68.73 ? 148 LEU B C   1 
ATOM   2912 O O   . LEU B 2 148 ? 108.731 93.607  128.845 1.00 67.64 ? 148 LEU B O   1 
ATOM   2913 C CB  . LEU B 2 148 ? 108.716 96.517  127.208 1.00 62.22 ? 148 LEU B CB  1 
ATOM   2914 N N   . LEU B 2 149 ? 109.923 95.263  129.817 1.00 69.64 ? 149 LEU B N   1 
ATOM   2915 C CA  . LEU B 2 149 ? 110.798 94.319  130.507 1.00 68.02 ? 149 LEU B CA  1 
ATOM   2916 C C   . LEU B 2 149 ? 110.011 93.444  131.476 1.00 69.76 ? 149 LEU B C   1 
ATOM   2917 O O   . LEU B 2 149 ? 110.254 92.237  131.564 1.00 71.17 ? 149 LEU B O   1 
ATOM   2918 C CB  . LEU B 2 149 ? 111.909 95.072  131.245 1.00 64.99 ? 149 LEU B CB  1 
ATOM   2919 C CG  . LEU B 2 149 ? 112.913 94.246  132.065 1.00 66.98 ? 149 LEU B CG  1 
ATOM   2920 C CD1 . LEU B 2 149 ? 113.713 93.328  131.158 1.00 69.57 ? 149 LEU B CD1 1 
ATOM   2921 C CD2 . LEU B 2 149 ? 113.847 95.146  132.856 1.00 67.23 ? 149 LEU B CD2 1 
ATOM   2922 N N   . ALA B 2 150 ? 109.066 94.035  132.210 1.00 70.94 ? 150 ALA B N   1 
ATOM   2923 C CA  . ALA B 2 150 ? 108.325 93.284  133.216 1.00 70.52 ? 150 ALA B CA  1 
ATOM   2924 C C   . ALA B 2 150 ? 107.467 92.206  132.577 1.00 69.04 ? 150 ALA B C   1 
ATOM   2925 O O   . ALA B 2 150 ? 107.445 91.062  133.048 1.00 69.50 ? 150 ALA B O   1 
ATOM   2926 C CB  . ALA B 2 150 ? 107.459 94.231  134.045 1.00 69.38 ? 150 ALA B CB  1 
ATOM   2927 N N   . GLU B 2 151 ? 106.756 92.544  131.497 1.00 65.87 ? 151 GLU B N   1 
ATOM   2928 C CA  . GLU B 2 151 ? 105.952 91.527  130.826 1.00 70.12 ? 151 GLU B CA  1 
ATOM   2929 C C   . GLU B 2 151 ? 106.839 90.448  130.216 1.00 73.28 ? 151 GLU B C   1 
ATOM   2930 O O   . GLU B 2 151 ? 106.486 89.264  130.240 1.00 72.19 ? 151 GLU B O   1 
ATOM   2931 C CB  . GLU B 2 151 ? 105.040 92.158  129.769 1.00 70.98 ? 151 GLU B CB  1 
ATOM   2932 C CG  . GLU B 2 151 ? 105.737 92.854  128.617 1.00 72.47 ? 151 GLU B CG  1 
ATOM   2933 C CD  . GLU B 2 151 ? 104.764 93.363  127.571 1.00 72.44 ? 151 GLU B CD  1 
ATOM   2934 O OE1 . GLU B 2 151 ? 103.586 93.597  127.916 1.00 69.87 ? 151 GLU B OE1 1 
ATOM   2935 O OE2 . GLU B 2 151 ? 105.176 93.527  126.404 1.00 72.39 ? 151 GLU B OE2 1 
ATOM   2936 N N   . LYS B 2 152 ? 108.008 90.830  129.687 1.00 71.43 ? 152 LYS B N   1 
ATOM   2937 C CA  . LYS B 2 152 ? 108.903 89.831  129.112 1.00 68.47 ? 152 LYS B CA  1 
ATOM   2938 C C   . LYS B 2 152 ? 109.427 88.864  130.173 1.00 70.11 ? 152 LYS B C   1 
ATOM   2939 O O   . LYS B 2 152 ? 109.459 87.649  129.947 1.00 69.61 ? 152 LYS B O   1 
ATOM   2940 C CB  . LYS B 2 152 ? 110.056 90.523  128.384 1.00 69.20 ? 152 LYS B CB  1 
ATOM   2941 C CG  . LYS B 2 152 ? 110.888 89.584  127.509 1.00 74.03 ? 152 LYS B CG  1 
ATOM   2942 C CD  . LYS B 2 152 ? 112.015 90.292  126.752 1.00 71.88 ? 152 LYS B CD  1 
ATOM   2943 C CE  . LYS B 2 152 ? 111.515 91.288  125.713 1.00 72.03 ? 152 LYS B CE  1 
ATOM   2944 N NZ  . LYS B 2 152 ? 112.638 91.886  124.942 1.00 70.10 ? 152 LYS B NZ  1 
ATOM   2945 N N   . VAL B 2 153 ? 109.833 89.376  131.338 1.00 72.96 ? 153 VAL B N   1 
ATOM   2946 C CA  . VAL B 2 153 ? 110.348 88.489  132.385 1.00 73.29 ? 153 VAL B CA  1 
ATOM   2947 C C   . VAL B 2 153 ? 109.225 87.632  132.960 1.00 75.09 ? 153 VAL B C   1 
ATOM   2948 O O   . VAL B 2 153 ? 109.434 86.457  133.286 1.00 71.83 ? 153 VAL B O   1 
ATOM   2949 C CB  . VAL B 2 153 ? 111.091 89.270  133.493 1.00 72.87 ? 153 VAL B CB  1 
ATOM   2950 C CG1 . VAL B 2 153 ? 111.888 88.308  134.381 1.00 71.64 ? 153 VAL B CG1 1 
ATOM   2951 C CG2 . VAL B 2 153 ? 112.093 90.298  132.920 1.00 71.51 ? 153 VAL B CG2 1 
ATOM   2952 N N   . LEU B 2 154 ? 108.025 88.201  133.117 1.00 77.24 ? 154 LEU B N   1 
ATOM   2953 C CA  . LEU B 2 154 ? 106.901 87.404  133.606 1.00 75.93 ? 154 LEU B CA  1 
ATOM   2954 C C   . LEU B 2 154 ? 106.553 86.289  132.628 1.00 75.47 ? 154 LEU B C   1 
ATOM   2955 O O   . LEU B 2 154 ? 106.226 85.171  133.044 1.00 74.40 ? 154 LEU B O   1 
ATOM   2956 C CB  . LEU B 2 154 ? 105.679 88.292  133.862 1.00 73.22 ? 154 LEU B CB  1 
ATOM   2957 C CG  . LEU B 2 154 ? 105.443 88.801  135.291 1.00 75.21 ? 154 LEU B CG  1 
ATOM   2958 C CD1 . LEU B 2 154 ? 106.738 89.215  135.986 1.00 75.32 ? 154 LEU B CD1 1 
ATOM   2959 C CD2 . LEU B 2 154 ? 104.448 89.950  135.293 1.00 73.52 ? 154 LEU B CD2 1 
ATOM   2960 N N   . ALA B 2 155 ? 106.613 86.572  131.324 1.00 73.80 ? 155 ALA B N   1 
ATOM   2961 C CA  . ALA B 2 155 ? 106.429 85.516  130.335 1.00 75.47 ? 155 ALA B CA  1 
ATOM   2962 C C   . ALA B 2 155 ? 107.530 84.469  130.442 1.00 76.82 ? 155 ALA B C   1 
ATOM   2963 O O   . ALA B 2 155 ? 107.261 83.264  130.374 1.00 78.21 ? 155 ALA B O   1 
ATOM   2964 C CB  . ALA B 2 155 ? 106.395 86.116  128.930 1.00 74.61 ? 155 ALA B CB  1 
ATOM   2965 N N   . GLY B 2 156 ? 108.776 84.908  130.610 1.00 72.04 ? 156 GLY B N   1 
ATOM   2966 C CA  . GLY B 2 156 ? 109.891 84.001  130.773 1.00 73.25 ? 156 GLY B CA  1 
ATOM   2967 C C   . GLY B 2 156 ? 110.389 83.346  129.503 1.00 75.22 ? 156 GLY B C   1 
ATOM   2968 O O   . GLY B 2 156 ? 111.235 82.446  129.586 1.00 74.26 ? 156 GLY B O   1 
ATOM   2969 N N   . LYS B 2 157 ? 109.890 83.754  128.332 1.00 77.09 ? 157 LYS B N   1 
ATOM   2970 C CA  . LYS B 2 157 ? 110.353 83.157  127.083 1.00 76.98 ? 157 LYS B CA  1 
ATOM   2971 C C   . LYS B 2 157 ? 111.829 83.450  126.844 1.00 75.14 ? 157 LYS B C   1 
ATOM   2972 O O   . LYS B 2 157 ? 112.589 82.560  126.442 1.00 71.90 ? 157 LYS B O   1 
ATOM   2973 C CB  . LYS B 2 157 ? 109.511 83.669  125.915 1.00 71.54 ? 157 LYS B CB  1 
ATOM   2974 N N   . SER B 2 158 ? 112.250 84.689  127.089 1.00 77.16 ? 158 SER B N   1 
ATOM   2975 C CA  . SER B 2 158 ? 113.641 85.097  126.956 1.00 76.02 ? 158 SER B CA  1 
ATOM   2976 C C   . SER B 2 158 ? 114.342 85.019  128.305 1.00 76.23 ? 158 SER B C   1 
ATOM   2977 O O   . SER B 2 158 ? 113.701 85.042  129.360 1.00 71.15 ? 158 SER B O   1 
ATOM   2978 C CB  . SER B 2 158 ? 113.734 86.520  126.411 1.00 76.74 ? 158 SER B CB  1 
ATOM   2979 O OG  . SER B 2 158 ? 113.298 87.452  127.384 1.00 78.95 ? 158 SER B OG  1 
ATOM   2980 N N   . LYS B 2 159 ? 115.670 84.920  128.259 1.00 80.66 ? 159 LYS B N   1 
ATOM   2981 C CA  . LYS B 2 159 ? 116.510 84.831  129.449 1.00 78.70 ? 159 LYS B CA  1 
ATOM   2982 C C   . LYS B 2 159 ? 117.627 85.859  129.357 1.00 78.74 ? 159 LYS B C   1 
ATOM   2983 O O   . LYS B 2 159 ? 118.392 85.865  128.386 1.00 75.31 ? 159 LYS B O   1 
ATOM   2984 C CB  . LYS B 2 159 ? 117.091 83.424  129.602 1.00 73.66 ? 159 LYS B CB  1 
ATOM   2985 N N   . ILE B 2 160 ? 117.726 86.718  130.373 1.00 75.03 ? 160 ILE B N   1 
ATOM   2986 C CA  . ILE B 2 160 ? 118.906 87.568  130.516 1.00 73.18 ? 160 ILE B CA  1 
ATOM   2987 C C   . ILE B 2 160 ? 120.137 86.710  130.781 1.00 76.04 ? 160 ILE B C   1 
ATOM   2988 O O   . ILE B 2 160 ? 121.265 87.102  130.459 1.00 75.44 ? 160 ILE B O   1 
ATOM   2989 C CB  . ILE B 2 160 ? 118.693 88.614  131.633 1.00 72.29 ? 160 ILE B CB  1 
ATOM   2990 C CG1 . ILE B 2 160 ? 117.487 89.517  131.338 1.00 71.58 ? 160 ILE B CG1 1 
ATOM   2991 C CG2 . ILE B 2 160 ? 119.959 89.463  131.852 1.00 71.80 ? 160 ILE B CG2 1 
ATOM   2992 C CD1 . ILE B 2 160 ? 116.531 89.630  132.495 1.00 72.17 ? 160 ILE B CD1 1 
ATOM   2993 N N   . GLU B 2 161 ? 119.939 85.539  131.403 1.00 81.10 ? 161 GLU B N   1 
ATOM   2994 C CA  . GLU B 2 161 ? 121.042 84.619  131.664 1.00 77.89 ? 161 GLU B CA  1 
ATOM   2995 C C   . GLU B 2 161 ? 121.753 84.217  130.377 1.00 80.03 ? 161 GLU B C   1 
ATOM   2996 O O   . GLU B 2 161 ? 122.978 84.043  130.366 1.00 77.87 ? 161 GLU B O   1 
ATOM   2997 C CB  . GLU B 2 161 ? 120.519 83.379  132.389 1.00 75.68 ? 161 GLU B CB  1 
ATOM   2998 N N   . ASP B 2 162 ? 121.003 84.061  129.284 1.00 81.07 ? 162 ASP B N   1 
ATOM   2999 C CA  . ASP B 2 162 ? 121.617 83.678  128.017 1.00 79.53 ? 162 ASP B CA  1 
ATOM   3000 C C   . ASP B 2 162 ? 122.546 84.769  127.499 1.00 79.15 ? 162 ASP B C   1 
ATOM   3001 O O   . ASP B 2 162 ? 123.687 84.492  127.111 1.00 77.33 ? 162 ASP B O   1 
ATOM   3002 C CB  . ASP B 2 162 ? 120.533 83.367  126.985 1.00 74.82 ? 162 ASP B CB  1 
ATOM   3003 N N   . TYR B 2 163 ? 122.074 86.018  127.483 1.00 76.39 ? 163 TYR B N   1 
ATOM   3004 C CA  . TYR B 2 163 ? 122.878 87.106  126.936 1.00 76.65 ? 163 TYR B CA  1 
ATOM   3005 C C   . TYR B 2 163 ? 123.963 87.544  127.913 1.00 75.33 ? 163 TYR B C   1 
ATOM   3006 O O   . TYR B 2 163 ? 125.087 87.853  127.499 1.00 74.37 ? 163 TYR B O   1 
ATOM   3007 C CB  . TYR B 2 163 ? 121.964 88.275  126.568 1.00 73.36 ? 163 TYR B CB  1 
ATOM   3008 C CG  . TYR B 2 163 ? 121.159 88.038  125.307 1.00 74.48 ? 163 TYR B CG  1 
ATOM   3009 C CD1 . TYR B 2 163 ? 121.778 87.926  124.068 1.00 74.94 ? 163 TYR B CD1 1 
ATOM   3010 C CD2 . TYR B 2 163 ? 119.781 87.888  125.363 1.00 77.14 ? 163 TYR B CD2 1 
ATOM   3011 C CE1 . TYR B 2 163 ? 121.045 87.699  122.922 1.00 77.77 ? 163 TYR B CE1 1 
ATOM   3012 C CE2 . TYR B 2 163 ? 119.039 87.662  124.221 1.00 77.25 ? 163 TYR B CE2 1 
ATOM   3013 C CZ  . TYR B 2 163 ? 119.677 87.566  123.004 1.00 77.11 ? 163 TYR B CZ  1 
ATOM   3014 O OH  . TYR B 2 163 ? 118.943 87.338  121.863 1.00 74.33 ? 163 TYR B OH  1 
ATOM   3015 N N   . PHE B 2 164 ? 123.645 87.574  129.208 1.00 71.89 ? 164 PHE B N   1 
ATOM   3016 C CA  . PHE B 2 164 ? 124.574 87.907  130.279 1.00 73.59 ? 164 PHE B CA  1 
ATOM   3017 C C   . PHE B 2 164 ? 124.783 86.683  131.168 1.00 74.89 ? 164 PHE B C   1 
ATOM   3018 O O   . PHE B 2 164 ? 123.816 86.223  131.789 1.00 73.21 ? 164 PHE B O   1 
ATOM   3019 C CB  . PHE B 2 164 ? 124.048 89.075  131.134 1.00 74.35 ? 164 PHE B CB  1 
ATOM   3020 C CG  . PHE B 2 164 ? 123.964 90.385  130.399 1.00 74.34 ? 164 PHE B CG  1 
ATOM   3021 C CD1 . PHE B 2 164 ? 122.928 90.648  129.520 1.00 71.05 ? 164 PHE B CD1 1 
ATOM   3022 C CD2 . PHE B 2 164 ? 124.932 91.355  130.593 1.00 72.33 ? 164 PHE B CD2 1 
ATOM   3023 C CE1 . PHE B 2 164 ? 122.861 91.851  128.851 1.00 69.59 ? 164 PHE B CE1 1 
ATOM   3024 C CE2 . PHE B 2 164 ? 124.868 92.559  129.927 1.00 71.17 ? 164 PHE B CE2 1 
ATOM   3025 C CZ  . PHE B 2 164 ? 123.833 92.807  129.056 1.00 69.82 ? 164 PHE B CZ  1 
ATOM   3026 N N   . PRO B 2 165 ? 125.998 86.116  131.260 1.00 80.70 ? 165 PRO B N   1 
ATOM   3027 C CA  . PRO B 2 165 ? 126.180 84.982  132.187 1.00 79.62 ? 165 PRO B CA  1 
ATOM   3028 C C   . PRO B 2 165 ? 125.932 85.326  133.648 1.00 77.97 ? 165 PRO B C   1 
ATOM   3029 O O   . PRO B 2 165 ? 125.551 84.445  134.429 1.00 75.27 ? 165 PRO B O   1 
ATOM   3030 C CB  . PRO B 2 165 ? 127.639 84.568  131.945 1.00 78.48 ? 165 PRO B CB  1 
ATOM   3031 C CG  . PRO B 2 165 ? 127.939 85.029  130.578 1.00 75.50 ? 165 PRO B CG  1 
ATOM   3032 C CD  . PRO B 2 165 ? 127.215 86.327  130.452 1.00 78.03 ? 165 PRO B CD  1 
ATOM   3033 N N   . GLU B 2 166 ? 126.144 86.584  134.044 1.00 74.54 ? 166 GLU B N   1 
ATOM   3034 C CA  . GLU B 2 166 ? 126.119 86.928  135.465 1.00 71.62 ? 166 GLU B CA  1 
ATOM   3035 C C   . GLU B 2 166 ? 124.710 86.855  136.044 1.00 74.06 ? 166 GLU B C   1 
ATOM   3036 O O   . GLU B 2 166 ? 124.543 86.592  137.241 1.00 71.44 ? 166 GLU B O   1 
ATOM   3037 C CB  . GLU B 2 166 ? 126.716 88.322  135.703 1.00 71.32 ? 166 GLU B CB  1 
ATOM   3038 C CG  . GLU B 2 166 ? 128.250 88.493  135.538 1.00 75.57 ? 166 GLU B CG  1 
ATOM   3039 C CD  . GLU B 2 166 ? 128.835 87.981  134.232 1.00 76.15 ? 166 GLU B CD  1 
ATOM   3040 O OE1 . GLU B 2 166 ? 130.078 87.923  134.124 1.00 74.19 ? 166 GLU B OE1 1 
ATOM   3041 O OE2 . GLU B 2 166 ? 128.059 87.644  133.314 1.00 74.54 ? 166 GLU B OE2 1 
ATOM   3042 N N   . PHE B 2 167 ? 123.682 87.099  135.226 1.00 76.43 ? 167 PHE B N   1 
ATOM   3043 C CA  . PHE B 2 167 ? 122.317 87.046  135.744 1.00 74.09 ? 167 PHE B CA  1 
ATOM   3044 C C   . PHE B 2 167 ? 121.936 85.634  136.168 1.00 76.15 ? 167 PHE B C   1 
ATOM   3045 O O   . PHE B 2 167 ? 121.117 85.454  137.078 1.00 78.10 ? 167 PHE B O   1 
ATOM   3046 C CB  . PHE B 2 167 ? 121.316 87.546  134.709 1.00 72.04 ? 167 PHE B CB  1 
ATOM   3047 C CG  . PHE B 2 167 ? 119.890 87.461  135.178 1.00 72.92 ? 167 PHE B CG  1 
ATOM   3048 C CD1 . PHE B 2 167 ? 119.426 88.309  136.168 1.00 71.06 ? 167 PHE B CD1 1 
ATOM   3049 C CD2 . PHE B 2 167 ? 119.035 86.494  134.679 1.00 73.69 ? 167 PHE B CD2 1 
ATOM   3050 C CE1 . PHE B 2 167 ? 118.124 88.226  136.616 1.00 73.23 ? 167 PHE B CE1 1 
ATOM   3051 C CE2 . PHE B 2 167 ? 117.729 86.407  135.125 1.00 72.96 ? 167 PHE B CE2 1 
ATOM   3052 C CZ  . PHE B 2 167 ? 117.276 87.271  136.097 1.00 73.29 ? 167 PHE B CZ  1 
ATOM   3053 N N   . ALA B 2 168 ? 122.501 84.620  135.502 1.00 76.16 ? 168 ALA B N   1 
ATOM   3054 C CA  . ALA B 2 168 ? 122.146 83.235  135.804 1.00 76.02 ? 168 ALA B CA  1 
ATOM   3055 C C   . ALA B 2 168 ? 122.475 82.880  137.249 1.00 76.00 ? 168 ALA B C   1 
ATOM   3056 O O   . ALA B 2 168 ? 121.785 82.060  137.866 1.00 75.32 ? 168 ALA B O   1 
ATOM   3057 C CB  . ALA B 2 168 ? 122.868 82.293  134.841 1.00 75.95 ? 168 ALA B CB  1 
ATOM   3058 N N   . ARG B 2 169 ? 123.528 83.484  137.800 1.00 74.66 ? 169 ARG B N   1 
ATOM   3059 C CA  . ARG B 2 169 ? 123.853 83.408  139.220 1.00 75.24 ? 169 ARG B CA  1 
ATOM   3060 C C   . ARG B 2 169 ? 123.968 84.827  139.757 1.00 74.63 ? 169 ARG B C   1 
ATOM   3061 O O   . ARG B 2 169 ? 125.034 85.444  139.660 1.00 72.87 ? 169 ARG B O   1 
ATOM   3062 C CB  . ARG B 2 169 ? 125.155 82.637  139.445 1.00 72.42 ? 169 ARG B CB  1 
ATOM   3063 N N   . TYR B 2 170 ? 122.876 85.337  140.325 1.00 73.00 ? 170 TYR B N   1 
ATOM   3064 C CA  . TYR B 2 170 ? 122.845 86.694  140.854 1.00 73.25 ? 170 TYR B CA  1 
ATOM   3065 C C   . TYR B 2 170 ? 121.879 86.728  142.028 1.00 73.96 ? 170 TYR B C   1 
ATOM   3066 O O   . TYR B 2 170 ? 120.850 86.047  142.029 1.00 72.69 ? 170 TYR B O   1 
ATOM   3067 C CB  . TYR B 2 170 ? 122.435 87.706  139.775 1.00 71.41 ? 170 TYR B CB  1 
ATOM   3068 C CG  . TYR B 2 170 ? 122.396 89.143  140.249 1.00 72.61 ? 170 TYR B CG  1 
ATOM   3069 C CD1 . TYR B 2 170 ? 123.545 89.919  140.257 1.00 71.59 ? 170 TYR B CD1 1 
ATOM   3070 C CD2 . TYR B 2 170 ? 121.210 89.727  140.676 1.00 74.66 ? 170 TYR B CD2 1 
ATOM   3071 C CE1 . TYR B 2 170 ? 123.520 91.231  140.687 1.00 70.48 ? 170 TYR B CE1 1 
ATOM   3072 C CE2 . TYR B 2 170 ? 121.176 91.040  141.108 1.00 73.43 ? 170 TYR B CE2 1 
ATOM   3073 C CZ  . TYR B 2 170 ? 122.333 91.786  141.110 1.00 71.89 ? 170 TYR B CZ  1 
ATOM   3074 O OH  . TYR B 2 170 ? 122.307 93.093  141.538 1.00 69.64 ? 170 TYR B OH  1 
ATOM   3075 N N   . THR B 2 171 ? 122.221 87.545  143.022 1.00 74.46 ? 171 THR B N   1 
ATOM   3076 C CA  . THR B 2 171 ? 121.480 87.642  144.273 1.00 74.50 ? 171 THR B CA  1 
ATOM   3077 C C   . THR B 2 171 ? 120.630 88.904  144.265 1.00 73.69 ? 171 THR B C   1 
ATOM   3078 O O   . THR B 2 171 ? 121.151 90.008  144.076 1.00 73.45 ? 171 THR B O   1 
ATOM   3079 C CB  . THR B 2 171 ? 122.432 87.660  145.471 1.00 72.80 ? 171 THR B CB  1 
ATOM   3080 N N   . THR B 2 172 ? 119.328 88.735  144.472 1.00 73.82 ? 172 THR B N   1 
ATOM   3081 C CA  . THR B 2 172 ? 118.426 89.875  144.498 1.00 75.44 ? 172 THR B CA  1 
ATOM   3082 C C   . THR B 2 172 ? 118.732 90.744  145.719 1.00 75.07 ? 172 THR B C   1 
ATOM   3083 O O   . THR B 2 172 ? 118.897 90.215  146.823 1.00 75.15 ? 172 THR B O   1 
ATOM   3084 C CB  . THR B 2 172 ? 116.973 89.397  144.546 1.00 77.54 ? 172 THR B CB  1 
ATOM   3085 O OG1 . THR B 2 172 ? 116.728 88.503  143.454 1.00 77.85 ? 172 THR B OG1 1 
ATOM   3086 C CG2 . THR B 2 172 ? 116.004 90.568  144.446 1.00 74.36 ? 172 THR B CG2 1 
ATOM   3087 N N   . PRO B 2 173 ? 118.798 92.084  145.568 1.00 77.47 ? 173 PRO B N   1 
ATOM   3088 C CA  . PRO B 2 173 ? 119.170 92.878  146.740 1.00 76.15 ? 173 PRO B CA  1 
ATOM   3089 C C   . PRO B 2 173 ? 117.982 93.205  147.639 1.00 77.18 ? 173 PRO B C   1 
ATOM   3090 O O   . PRO B 2 173 ? 118.047 92.940  148.839 1.00 79.08 ? 173 PRO B O   1 
ATOM   3091 C CB  . PRO B 2 173 ? 119.749 94.143  146.114 1.00 74.53 ? 173 PRO B CB  1 
ATOM   3092 C CG  . PRO B 2 173 ? 118.995 94.294  144.807 1.00 78.50 ? 173 PRO B CG  1 
ATOM   3093 C CD  . PRO B 2 173 ? 118.303 92.976  144.504 1.00 78.99 ? 173 PRO B CD  1 
ATOM   3094 N N   . GLU B 2 182 ? 105.567 93.710  143.190 1.00 73.04 ? 182 GLU B N   1 
ATOM   3095 C CA  . GLU B 2 182 ? 106.700 93.464  142.306 1.00 75.43 ? 182 GLU B CA  1 
ATOM   3096 C C   . GLU B 2 182 ? 107.153 92.014  142.373 1.00 75.42 ? 182 GLU B C   1 
ATOM   3097 O O   . GLU B 2 182 ? 107.320 91.458  143.458 1.00 74.30 ? 182 GLU B O   1 
ATOM   3098 C CB  . GLU B 2 182 ? 107.875 94.373  142.666 1.00 75.66 ? 182 GLU B CB  1 
ATOM   3099 C CG  . GLU B 2 182 ? 108.872 94.567  141.530 1.00 75.35 ? 182 GLU B CG  1 
ATOM   3100 C CD  . GLU B 2 182 ? 109.808 95.741  141.752 1.00 76.08 ? 182 GLU B CD  1 
ATOM   3101 O OE1 . GLU B 2 182 ? 109.775 96.340  142.848 1.00 76.17 ? 182 GLU B OE1 1 
ATOM   3102 O OE2 . GLU B 2 182 ? 110.582 96.065  140.828 1.00 74.54 ? 182 GLU B OE2 1 
ATOM   3103 N N   . ASP B 2 183 ? 107.355 91.405  141.211 1.00 78.05 ? 183 ASP B N   1 
ATOM   3104 C CA  . ASP B 2 183 ? 107.861 90.043  141.183 1.00 77.60 ? 183 ASP B CA  1 
ATOM   3105 C C   . ASP B 2 183 ? 109.336 90.032  141.591 1.00 78.37 ? 183 ASP B C   1 
ATOM   3106 O O   . ASP B 2 183 ? 110.087 90.950  141.226 1.00 78.45 ? 183 ASP B O   1 
ATOM   3107 C CB  . ASP B 2 183 ? 107.692 89.435  139.790 1.00 76.12 ? 183 ASP B CB  1 
ATOM   3108 C CG  . ASP B 2 183 ? 106.286 88.924  139.544 1.00 77.17 ? 183 ASP B CG  1 
ATOM   3109 O OD1 . ASP B 2 183 ? 105.442 89.710  139.066 1.00 78.36 ? 183 ASP B OD1 1 
ATOM   3110 O OD2 . ASP B 2 183 ? 106.026 87.737  139.830 1.00 76.79 ? 183 ASP B OD2 1 
ATOM   3111 N N   . PRO B 2 184 ? 109.797 89.016  142.336 1.00 78.99 ? 184 PRO B N   1 
ATOM   3112 C CA  . PRO B 2 184 ? 111.214 89.026  142.730 1.00 76.14 ? 184 PRO B CA  1 
ATOM   3113 C C   . PRO B 2 184 ? 112.150 88.826  141.553 1.00 76.93 ? 184 PRO B C   1 
ATOM   3114 O O   . PRO B 2 184 ? 113.246 89.397  141.535 1.00 76.62 ? 184 PRO B O   1 
ATOM   3115 C CB  . PRO B 2 184 ? 111.313 87.883  143.752 1.00 76.05 ? 184 PRO B CB  1 
ATOM   3116 C CG  . PRO B 2 184 ? 110.053 87.085  143.623 1.00 78.01 ? 184 PRO B CG  1 
ATOM   3117 C CD  . PRO B 2 184 ? 109.191 87.691  142.564 1.00 78.06 ? 184 PRO B CD  1 
ATOM   3118 N N   . ARG B 2 185 ? 111.739 88.036  140.558 1.00 75.12 ? 185 ARG B N   1 
ATOM   3119 C CA  . ARG B 2 185 ? 112.535 87.906  139.342 1.00 76.65 ? 185 ARG B CA  1 
ATOM   3120 C C   . ARG B 2 185 ? 112.635 89.238  138.610 1.00 76.88 ? 185 ARG B C   1 
ATOM   3121 O O   . ARG B 2 185 ? 113.694 89.580  138.070 1.00 74.01 ? 185 ARG B O   1 
ATOM   3122 C CB  . ARG B 2 185 ? 111.928 86.838  138.432 1.00 73.62 ? 185 ARG B CB  1 
ATOM   3123 N N   . VAL B 2 186 ? 111.540 90.002  138.580 1.00 74.87 ? 186 VAL B N   1 
ATOM   3124 C CA  . VAL B 2 186 ? 111.560 91.316  137.944 1.00 71.93 ? 186 VAL B CA  1 
ATOM   3125 C C   . VAL B 2 186 ? 112.520 92.245  138.675 1.00 70.93 ? 186 VAL B C   1 
ATOM   3126 O O   . VAL B 2 186 ? 113.311 92.960  138.044 1.00 73.98 ? 186 VAL B O   1 
ATOM   3127 C CB  . VAL B 2 186 ? 110.135 91.897  137.884 1.00 70.38 ? 186 VAL B CB  1 
ATOM   3128 C CG1 . VAL B 2 186 ? 110.154 93.382  137.517 1.00 72.74 ? 186 VAL B CG1 1 
ATOM   3129 C CG2 . VAL B 2 186 ? 109.295 91.124  136.883 1.00 71.52 ? 186 VAL B CG2 1 
ATOM   3130 N N   . THR B 2 187 ? 112.466 92.256  140.011 1.00 68.18 ? 187 THR B N   1 
ATOM   3131 C CA  . THR B 2 187 ? 113.386 93.097  140.773 1.00 71.64 ? 187 THR B CA  1 
ATOM   3132 C C   . THR B 2 187 ? 114.833 92.672  140.547 1.00 71.92 ? 187 THR B C   1 
ATOM   3133 O O   . THR B 2 187 ? 115.719 93.519  140.389 1.00 71.01 ? 187 THR B O   1 
ATOM   3134 C CB  . THR B 2 187 ? 113.043 93.046  142.262 1.00 72.54 ? 187 THR B CB  1 
ATOM   3135 O OG1 . THR B 2 187 ? 111.637 93.254  142.438 1.00 72.72 ? 187 THR B OG1 1 
ATOM   3136 C CG2 . THR B 2 187 ? 113.807 94.119  143.032 1.00 69.80 ? 187 THR B CG2 1 
ATOM   3137 N N   . ARG B 2 188 ? 115.084 91.363  140.508 1.00 71.18 ? 188 ARG B N   1 
ATOM   3138 C CA  . ARG B 2 188 ? 116.430 90.855  140.267 1.00 73.86 ? 188 ARG B CA  1 
ATOM   3139 C C   . ARG B 2 188 ? 116.955 91.299  138.907 1.00 75.47 ? 188 ARG B C   1 
ATOM   3140 O O   . ARG B 2 188 ? 118.079 91.812  138.799 1.00 73.29 ? 188 ARG B O   1 
ATOM   3141 C CB  . ARG B 2 188 ? 116.404 89.331  140.364 1.00 73.30 ? 188 ARG B CB  1 
ATOM   3142 C CG  . ARG B 2 188 ? 117.757 88.644  140.443 1.00 72.97 ? 188 ARG B CG  1 
ATOM   3143 C CD  . ARG B 2 188 ? 117.595 87.125  140.406 1.00 72.80 ? 188 ARG B CD  1 
ATOM   3144 N NE  . ARG B 2 188 ? 118.780 86.450  139.886 1.00 73.12 ? 188 ARG B NE  1 
ATOM   3145 C CZ  . ARG B 2 188 ? 118.803 85.231  139.356 1.00 73.63 ? 188 ARG B CZ  1 
ATOM   3146 N NH1 . ARG B 2 188 ? 117.712 84.485  139.262 1.00 72.54 ? 188 ARG B NH1 1 
ATOM   3147 N NH2 . ARG B 2 188 ? 119.957 84.743  138.912 1.00 71.84 ? 188 ARG B NH2 1 
ATOM   3148 N N   . ALA B 2 189 ? 116.144 91.127  137.859 1.00 70.91 ? 189 ALA B N   1 
ATOM   3149 C CA  . ALA B 2 189 ? 116.569 91.497  136.514 1.00 67.82 ? 189 ALA B CA  1 
ATOM   3150 C C   . ALA B 2 189 ? 116.815 92.994  136.402 1.00 67.14 ? 189 ALA B C   1 
ATOM   3151 O O   . ALA B 2 189 ? 117.831 93.424  135.837 1.00 66.47 ? 189 ALA B O   1 
ATOM   3152 C CB  . ALA B 2 189 ? 115.519 91.056  135.497 1.00 65.05 ? 189 ALA B CB  1 
ATOM   3153 N N   . LYS B 2 190 ? 115.901 93.807  136.939 1.00 66.11 ? 190 LYS B N   1 
ATOM   3154 C CA  . LYS B 2 190 ? 116.059 95.251  136.816 1.00 67.44 ? 190 LYS B CA  1 
ATOM   3155 C C   . LYS B 2 190 ? 117.268 95.735  137.609 1.00 63.44 ? 190 LYS B C   1 
ATOM   3156 O O   . LYS B 2 190 ? 118.007 96.614  137.149 1.00 62.15 ? 190 LYS B O   1 
ATOM   3157 C CB  . LYS B 2 190 ? 114.766 95.964  137.238 1.00 61.58 ? 190 LYS B CB  1 
ATOM   3158 C CG  . LYS B 2 190 ? 114.650 96.362  138.710 1.00 66.21 ? 190 LYS B CG  1 
ATOM   3159 C CD  . LYS B 2 190 ? 113.220 96.735  139.136 1.00 66.07 ? 190 LYS B CD  1 
ATOM   3160 C CE  . LYS B 2 190 ? 112.495 97.632  138.142 1.00 63.39 ? 190 LYS B CE  1 
ATOM   3161 N NZ  . LYS B 2 190 ? 111.284 98.252  138.744 1.00 61.89 ? 190 LYS B NZ  1 
ATOM   3162 N N   . TYR B 2 191 ? 117.521 95.147  138.780 1.00 61.39 ? 191 TYR B N   1 
ATOM   3163 C CA  . TYR B 2 191 ? 118.679 95.574  139.555 1.00 65.31 ? 191 TYR B CA  1 
ATOM   3164 C C   . TYR B 2 191 ? 119.980 95.151  138.886 1.00 66.76 ? 191 TYR B C   1 
ATOM   3165 O O   . TYR B 2 191 ? 120.972 95.879  138.950 1.00 64.14 ? 191 TYR B O   1 
ATOM   3166 C CB  . TYR B 2 191 ? 118.595 95.043  140.985 1.00 67.37 ? 191 TYR B CB  1 
ATOM   3167 C CG  . TYR B 2 191 ? 117.929 96.024  141.925 1.00 67.67 ? 191 TYR B CG  1 
ATOM   3168 C CD1 . TYR B 2 191 ? 116.547 96.112  142.007 1.00 64.47 ? 191 TYR B CD1 1 
ATOM   3169 C CD2 . TYR B 2 191 ? 118.686 96.883  142.707 1.00 66.70 ? 191 TYR B CD2 1 
ATOM   3170 C CE1 . TYR B 2 191 ? 115.940 97.012  142.856 1.00 64.71 ? 191 TYR B CE1 1 
ATOM   3171 C CE2 . TYR B 2 191 ? 118.088 97.786  143.559 1.00 64.25 ? 191 TYR B CE2 1 
ATOM   3172 C CZ  . TYR B 2 191 ? 116.715 97.847  143.628 1.00 66.76 ? 191 TYR B CZ  1 
ATOM   3173 O OH  . TYR B 2 191 ? 116.113 98.748  144.476 1.00 67.83 ? 191 TYR B OH  1 
ATOM   3174 N N   . PHE B 2 192 ? 119.998 93.991  138.222 1.00 69.99 ? 192 PHE B N   1 
ATOM   3175 C CA  . PHE B 2 192 ? 121.184 93.613  137.450 1.00 70.27 ? 192 PHE B CA  1 
ATOM   3176 C C   . PHE B 2 192 ? 121.430 94.578  136.292 1.00 69.39 ? 192 PHE B C   1 
ATOM   3177 O O   . PHE B 2 192 ? 122.576 95.005  136.049 1.00 67.08 ? 192 PHE B O   1 
ATOM   3178 C CB  . PHE B 2 192 ? 121.027 92.187  136.925 1.00 71.51 ? 192 PHE B CB  1 
ATOM   3179 C CG  . PHE B 2 192 ? 122.168 91.729  136.065 1.00 70.69 ? 192 PHE B CG  1 
ATOM   3180 C CD1 . PHE B 2 192 ? 123.462 91.707  136.554 1.00 69.73 ? 192 PHE B CD1 1 
ATOM   3181 C CD2 . PHE B 2 192 ? 121.944 91.330  134.760 1.00 68.60 ? 192 PHE B CD2 1 
ATOM   3182 C CE1 . PHE B 2 192 ? 124.507 91.289  135.760 1.00 71.87 ? 192 PHE B CE1 1 
ATOM   3183 C CE2 . PHE B 2 192 ? 122.986 90.911  133.962 1.00 70.08 ? 192 PHE B CE2 1 
ATOM   3184 C CZ  . PHE B 2 192 ? 124.270 90.892  134.462 1.00 70.89 ? 192 PHE B CZ  1 
ATOM   3185 N N   . ILE B 2 193 ? 120.362 94.921  135.562 1.00 65.35 ? 193 ILE B N   1 
ATOM   3186 C CA  . ILE B 2 193 ? 120.480 95.830  134.424 1.00 59.49 ? 193 ILE B CA  1 
ATOM   3187 C C   . ILE B 2 193 ? 121.000 97.182  134.887 1.00 59.64 ? 193 ILE B C   1 
ATOM   3188 O O   . ILE B 2 193 ? 121.867 97.784  134.245 1.00 59.05 ? 193 ILE B O   1 
ATOM   3189 C CB  . ILE B 2 193 ? 119.127 95.960  133.697 1.00 58.71 ? 193 ILE B CB  1 
ATOM   3190 C CG1 . ILE B 2 193 ? 118.756 94.654  132.986 1.00 58.02 ? 193 ILE B CG1 1 
ATOM   3191 C CG2 . ILE B 2 193 ? 119.152 97.098  132.682 1.00 63.05 ? 193 ILE B CG2 1 
ATOM   3192 C CD1 . ILE B 2 193 ? 117.264 94.443  132.849 1.00 57.95 ? 193 ILE B CD1 1 
ATOM   3193 N N   . ARG B 2 194 ? 120.479 97.679  136.010 1.00 54.99 ? 194 ARG B N   1 
ATOM   3194 C CA  . ARG B 2 194 ? 121.010 98.908  136.587 1.00 55.85 ? 194 ARG B CA  1 
ATOM   3195 C C   . ARG B 2 194 ? 122.467 98.738  137.000 1.00 53.31 ? 194 ARG B C   1 
ATOM   3196 O O   . ARG B 2 194 ? 123.302 99.608  136.721 1.00 50.67 ? 194 ARG B O   1 
ATOM   3197 C CB  . ARG B 2 194 ? 120.158 99.321  137.786 1.00 57.45 ? 194 ARG B CB  1 
ATOM   3198 C CG  . ARG B 2 194 ? 120.661 100.539 138.540 1.00 54.64 ? 194 ARG B CG  1 
ATOM   3199 C CD  . ARG B 2 194 ? 119.598 101.065 139.485 1.00 56.87 ? 194 ARG B CD  1 
ATOM   3200 N NE  . ARG B 2 194 ? 120.176 101.557 140.731 1.00 57.86 ? 194 ARG B NE  1 
ATOM   3201 C CZ  . ARG B 2 194 ? 120.581 100.797 141.741 1.00 56.83 ? 194 ARG B CZ  1 
ATOM   3202 N NH1 . ARG B 2 194 ? 120.503 99.474  141.698 1.00 56.57 ? 194 ARG B NH1 1 
ATOM   3203 N NH2 . ARG B 2 194 ? 121.086 101.378 142.825 1.00 57.05 ? 194 ARG B NH2 1 
ATOM   3204 N N   . LYS B 2 195 ? 122.790 97.603  137.627 1.00 62.71 ? 195 LYS B N   1 
ATOM   3205 C CA  . LYS B 2 195 ? 124.087 97.427  138.265 1.00 62.90 ? 195 LYS B CA  1 
ATOM   3206 C C   . LYS B 2 195 ? 125.217 97.446  137.252 1.00 65.91 ? 195 LYS B C   1 
ATOM   3207 O O   . LYS B 2 195 ? 126.315 97.911  137.561 1.00 64.82 ? 195 LYS B O   1 
ATOM   3208 C CB  . LYS B 2 195 ? 124.105 96.119  139.055 1.00 60.74 ? 195 LYS B CB  1 
ATOM   3209 N N   . GLU B 2 196 ? 124.972 96.949  136.037 1.00 66.62 ? 196 GLU B N   1 
ATOM   3210 C CA  . GLU B 2 196 ? 126.019 97.036  135.012 1.00 62.55 ? 196 GLU B CA  1 
ATOM   3211 C C   . GLU B 2 196 ? 126.371 98.490  134.682 1.00 62.52 ? 196 GLU B C   1 
ATOM   3212 O O   . GLU B 2 196 ? 127.556 98.862  134.635 1.00 56.18 ? 196 GLU B O   1 
ATOM   3213 C CB  . GLU B 2 196 ? 125.589 96.288  133.750 1.00 58.68 ? 196 GLU B CB  1 
ATOM   3214 C CG  . GLU B 2 196 ? 125.345 94.797  133.950 1.00 66.21 ? 196 GLU B CG  1 
ATOM   3215 C CD  . GLU B 2 196 ? 126.608 94.045  134.335 1.00 67.07 ? 196 GLU B CD  1 
ATOM   3216 O OE1 . GLU B 2 196 ? 126.636 93.440  135.426 1.00 63.44 ? 196 GLU B OE1 1 
ATOM   3217 O OE2 . GLU B 2 196 ? 127.575 94.059  133.543 1.00 63.95 ? 196 GLU B OE2 1 
ATOM   3218 N N   . PHE B 2 197 ? 125.356 99.333  134.474 1.00 57.79 ? 197 PHE B N   1 
ATOM   3219 C CA  . PHE B 2 197 ? 125.615 100.732 134.150 1.00 50.78 ? 197 PHE B CA  1 
ATOM   3220 C C   . PHE B 2 197 ? 126.264 101.460 135.319 1.00 55.24 ? 197 PHE B C   1 
ATOM   3221 O O   . PHE B 2 197 ? 127.216 102.229 135.133 1.00 54.65 ? 197 PHE B O   1 
ATOM   3222 C CB  . PHE B 2 197 ? 124.318 101.426 133.746 1.00 44.51 ? 197 PHE B CB  1 
ATOM   3223 C CG  . PHE B 2 197 ? 123.795 100.993 132.414 1.00 44.87 ? 197 PHE B CG  1 
ATOM   3224 C CD1 . PHE B 2 197 ? 124.364 101.463 131.247 1.00 45.22 ? 197 PHE B CD1 1 
ATOM   3225 C CD2 . PHE B 2 197 ? 122.736 100.112 132.329 1.00 48.78 ? 197 PHE B CD2 1 
ATOM   3226 C CE1 . PHE B 2 197 ? 123.885 101.063 130.025 1.00 53.58 ? 197 PHE B CE1 1 
ATOM   3227 C CE2 . PHE B 2 197 ? 122.252 99.708  131.109 1.00 48.00 ? 197 PHE B CE2 1 
ATOM   3228 C CZ  . PHE B 2 197 ? 122.828 100.183 129.956 1.00 53.92 ? 197 PHE B CZ  1 
ATOM   3229 N N   . VAL B 2 198 ? 125.764 101.232 136.535 1.00 60.99 ? 198 VAL B N   1 
ATOM   3230 C CA  . VAL B 2 198 ? 126.370 101.884 137.694 1.00 60.61 ? 198 VAL B CA  1 
ATOM   3231 C C   . VAL B 2 198 ? 127.774 101.343 137.945 1.00 60.96 ? 198 VAL B C   1 
ATOM   3232 O O   . VAL B 2 198 ? 128.612 102.035 138.522 1.00 61.77 ? 198 VAL B O   1 
ATOM   3233 C CB  . VAL B 2 198 ? 125.469 101.764 138.940 1.00 58.44 ? 198 VAL B CB  1 
ATOM   3234 C CG1 . VAL B 2 198 ? 126.036 102.604 140.087 1.00 55.76 ? 198 VAL B CG1 1 
ATOM   3235 C CG2 . VAL B 2 198 ? 124.066 102.264 138.614 1.00 57.02 ? 198 VAL B CG2 1 
ATOM   3236 N N   . ASP B 2 199 ? 128.068 100.118 137.500 1.00 58.90 ? 199 ASP B N   1 
ATOM   3237 C CA  . ASP B 2 199 ? 129.431 99.609  137.614 1.00 63.45 ? 199 ASP B CA  1 
ATOM   3238 C C   . ASP B 2 199 ? 130.367 100.364 136.678 1.00 66.07 ? 199 ASP B C   1 
ATOM   3239 O O   . ASP B 2 199 ? 131.478 100.746 137.075 1.00 64.86 ? 199 ASP B O   1 
ATOM   3240 C CB  . ASP B 2 199 ? 129.449 98.106  137.315 1.00 63.51 ? 199 ASP B CB  1 
ATOM   3241 C CG  . ASP B 2 199 ? 130.852 97.502  137.331 1.00 69.07 ? 199 ASP B CG  1 
ATOM   3242 O OD1 . ASP B 2 199 ? 131.797 98.126  137.862 1.00 69.52 ? 199 ASP B OD1 1 
ATOM   3243 O OD2 . ASP B 2 199 ? 131.010 96.383  136.799 1.00 66.53 ? 199 ASP B OD2 1 
ATOM   3244 N N   . ILE B 2 200 ? 129.940 100.576 135.427 1.00 63.00 ? 200 ILE B N   1 
ATOM   3245 C CA  . ILE B 2 200 ? 130.751 101.379 134.506 1.00 59.57 ? 200 ILE B CA  1 
ATOM   3246 C C   . ILE B 2 200 ? 130.933 102.789 135.053 1.00 59.70 ? 200 ILE B C   1 
ATOM   3247 O O   . ILE B 2 200 ? 132.009 103.386 134.924 1.00 57.04 ? 200 ILE B O   1 
ATOM   3248 C CB  . ILE B 2 200 ? 130.152 101.406 133.083 1.00 57.69 ? 200 ILE B CB  1 
ATOM   3249 C CG1 . ILE B 2 200 ? 129.982 99.984  132.515 1.00 58.24 ? 200 ILE B CG1 1 
ATOM   3250 C CG2 . ILE B 2 200 ? 131.016 102.314 132.178 1.00 55.70 ? 200 ILE B CG2 1 
ATOM   3251 C CD1 . ILE B 2 200 ? 129.242 99.909  131.189 1.00 56.27 ? 200 ILE B CD1 1 
ATOM   3252 N N   . SER B 2 201 ? 129.887 103.347 135.663 1.00 59.09 ? 201 SER B N   1 
ATOM   3253 C CA  . SER B 2 201 ? 130.008 104.679 136.253 1.00 59.29 ? 201 SER B CA  1 
ATOM   3254 C C   . SER B 2 201 ? 130.952 104.676 137.453 1.00 57.45 ? 201 SER B C   1 
ATOM   3255 O O   . SER B 2 201 ? 131.722 105.623 137.651 1.00 56.68 ? 201 SER B O   1 
ATOM   3256 C CB  . SER B 2 201 ? 128.632 105.202 136.664 1.00 56.94 ? 201 SER B CB  1 
ATOM   3257 O OG  . SER B 2 201 ? 128.076 104.392 137.683 1.00 60.36 ? 201 SER B OG  1 
ATOM   3258 N N   . THR B 2 202 ? 130.903 103.618 138.264 1.00 61.57 ? 202 THR B N   1 
ATOM   3259 C CA  . THR B 2 202 ? 131.613 103.599 139.539 1.00 63.81 ? 202 THR B CA  1 
ATOM   3260 C C   . THR B 2 202 ? 133.097 103.305 139.348 1.00 65.16 ? 202 THR B C   1 
ATOM   3261 O O   . THR B 2 202 ? 133.918 103.677 140.196 1.00 62.99 ? 202 THR B O   1 
ATOM   3262 C CB  . THR B 2 202 ? 130.948 102.566 140.465 1.00 62.89 ? 202 THR B CB  1 
ATOM   3263 O OG1 . THR B 2 202 ? 129.782 103.148 141.060 1.00 62.11 ? 202 THR B OG1 1 
ATOM   3264 C CG2 . THR B 2 202 ? 131.870 102.089 141.600 1.00 63.97 ? 202 THR B CG2 1 
ATOM   3265 N N   . ALA B 2 203 ? 133.459 102.634 138.244 1.00 68.68 ? 203 ALA B N   1 
ATOM   3266 C CA  . ALA B 2 203 ? 134.844 102.203 138.040 1.00 68.74 ? 203 ALA B CA  1 
ATOM   3267 C C   . ALA B 2 203 ? 135.828 103.371 138.061 1.00 67.15 ? 203 ALA B C   1 
ATOM   3268 O O   . ALA B 2 203 ? 136.985 103.204 138.465 1.00 68.03 ? 203 ALA B O   1 
ATOM   3269 C CB  . ALA B 2 203 ? 134.963 101.440 136.722 1.00 64.60 ? 203 ALA B CB  1 
ATOM   3270 N N   . SER B 2 204 ? 135.397 104.560 137.633 1.00 63.79 ? 204 SER B N   1 
ATOM   3271 C CA  . SER B 2 204 ? 136.280 105.720 137.719 1.00 65.96 ? 204 SER B CA  1 
ATOM   3272 C C   . SER B 2 204 ? 136.518 106.119 139.171 1.00 68.54 ? 204 SER B C   1 
ATOM   3273 O O   . SER B 2 204 ? 137.666 106.186 139.624 1.00 66.29 ? 204 SER B O   1 
ATOM   3274 C CB  . SER B 2 204 ? 135.700 106.895 136.929 1.00 65.20 ? 204 SER B CB  1 
ATOM   3275 O OG  . SER B 2 204 ? 136.081 108.131 137.508 1.00 63.59 ? 204 SER B OG  1 
ATOM   3276 N N   . GLY B 2 205 ? 135.446 106.388 139.915 1.00 71.04 ? 205 GLY B N   1 
ATOM   3277 C CA  . GLY B 2 205 ? 135.544 106.657 141.335 1.00 70.45 ? 205 GLY B CA  1 
ATOM   3278 C C   . GLY B 2 205 ? 136.073 108.026 141.708 1.00 72.43 ? 205 GLY B C   1 
ATOM   3279 O O   . GLY B 2 205 ? 136.300 108.276 142.899 1.00 68.24 ? 205 GLY B O   1 
ATOM   3280 N N   . ASP B 2 206 ? 136.279 108.920 140.737 1.00 74.01 ? 206 ASP B N   1 
ATOM   3281 C CA  . ASP B 2 206 ? 136.840 110.231 141.047 1.00 71.60 ? 206 ASP B CA  1 
ATOM   3282 C C   . ASP B 2 206 ? 135.870 111.069 141.873 1.00 72.32 ? 206 ASP B C   1 
ATOM   3283 O O   . ASP B 2 206 ? 136.290 111.825 142.757 1.00 72.34 ? 206 ASP B O   1 
ATOM   3284 C CB  . ASP B 2 206 ? 137.210 110.959 139.755 1.00 68.99 ? 206 ASP B CB  1 
ATOM   3285 N N   . GLY B 2 207 ? 134.573 110.955 141.594 1.00 66.10 ? 207 GLY B N   1 
ATOM   3286 C CA  . GLY B 2 207 ? 133.562 111.729 142.280 1.00 66.12 ? 207 GLY B CA  1 
ATOM   3287 C C   . GLY B 2 207 ? 133.287 113.096 141.692 1.00 67.05 ? 207 GLY B C   1 
ATOM   3288 O O   . GLY B 2 207 ? 132.378 113.784 142.173 1.00 66.67 ? 207 GLY B O   1 
ATOM   3289 N N   . ARG B 2 208 ? 134.038 113.515 140.670 1.00 68.08 ? 208 ARG B N   1 
ATOM   3290 C CA  . ARG B 2 208 ? 133.729 114.771 139.994 1.00 67.57 ? 208 ARG B CA  1 
ATOM   3291 C C   . ARG B 2 208 ? 132.383 114.695 139.285 1.00 66.19 ? 208 ARG B C   1 
ATOM   3292 O O   . ARG B 2 208 ? 131.680 115.705 139.161 1.00 65.77 ? 208 ARG B O   1 
ATOM   3293 C CB  . ARG B 2 208 ? 134.838 115.119 139.003 1.00 60.65 ? 208 ARG B CB  1 
ATOM   3294 N N   . HIS B 2 209 ? 132.085 113.501 138.757 1.00 51.28 ? 209 HIS B N   1 
ATOM   3295 C CA  . HIS B 2 209 ? 130.801 113.274 138.038 1.00 48.27 ? 209 HIS B CA  1 
ATOM   3296 C C   . HIS B 2 209 ? 130.232 111.923 138.480 1.00 53.01 ? 209 HIS B C   1 
ATOM   3297 O O   . HIS B 2 209 ? 131.014 110.956 138.622 1.00 57.92 ? 209 HIS B O   1 
ATOM   3298 C CB  . HIS B 2 209 ? 130.985 113.399 136.520 1.00 50.18 ? 209 HIS B CB  1 
ATOM   3299 C CG  . HIS B 2 209 ? 131.778 112.309 135.878 1.00 51.67 ? 209 HIS B CG  1 
ATOM   3300 N ND1 . HIS B 2 209 ? 132.812 111.643 136.500 1.00 46.90 ? 209 HIS B ND1 1 
ATOM   3301 C CD2 . HIS B 2 209 ? 131.686 111.783 134.650 1.00 56.11 ? 209 HIS B CD2 1 
ATOM   3302 C CE1 . HIS B 2 209 ? 133.315 110.742 135.668 1.00 47.78 ? 209 HIS B CE1 1 
ATOM   3303 N NE2 . HIS B 2 209 ? 132.646 110.811 134.538 1.00 53.98 ? 209 HIS B NE2 1 
ATOM   3304 N N   . ILE B 2 210 ? 128.919 111.853 138.692 1.00 48.66 ? 210 ILE B N   1 
ATOM   3305 C CA  . ILE B 2 210 ? 128.246 110.653 139.172 1.00 44.55 ? 210 ILE B CA  1 
ATOM   3306 C C   . ILE B 2 210 ? 127.009 110.409 138.321 1.00 42.50 ? 210 ILE B C   1 
ATOM   3307 O O   . ILE B 2 210 ? 126.474 111.318 137.684 1.00 47.75 ? 210 ILE B O   1 
ATOM   3308 C CB  . ILE B 2 210 ? 127.880 110.759 140.672 1.00 48.14 ? 210 ILE B CB  1 
ATOM   3309 C CG1 . ILE B 2 210 ? 126.715 111.740 140.892 1.00 50.39 ? 210 ILE B CG1 1 
ATOM   3310 C CG2 . ILE B 2 210 ? 129.118 111.153 141.474 1.00 47.40 ? 210 ILE B CG2 1 
ATOM   3311 C CD1 . ILE B 2 210 ? 126.569 112.244 142.323 1.00 51.54 ? 210 ILE B CD1 1 
ATOM   3312 N N   . CYS B 2 211 ? 126.557 109.156 138.324 1.00 43.16 ? 211 CYS B N   1 
ATOM   3313 C CA  . CYS B 2 211 ? 125.435 108.707 137.510 1.00 43.66 ? 211 CYS B CA  1 
ATOM   3314 C C   . CYS B 2 211 ? 124.205 108.546 138.390 1.00 48.99 ? 211 CYS B C   1 
ATOM   3315 O O   . CYS B 2 211 ? 124.277 107.918 139.452 1.00 53.79 ? 211 CYS B O   1 
ATOM   3316 C CB  . CYS B 2 211 ? 125.756 107.387 136.809 1.00 44.63 ? 211 CYS B CB  1 
ATOM   3317 S SG  . CYS B 2 211 ? 124.304 106.505 136.203 1.00 53.46 ? 211 CYS B SG  1 
ATOM   3318 N N   . TYR B 2 212 ? 123.083 109.119 137.945 1.00 39.62 ? 212 TYR B N   1 
ATOM   3319 C CA  . TYR B 2 212 ? 121.819 109.050 138.665 1.00 35.87 ? 212 TYR B CA  1 
ATOM   3320 C C   . TYR B 2 212 ? 120.902 108.057 137.969 1.00 35.05 ? 212 TYR B C   1 
ATOM   3321 O O   . TYR B 2 212 ? 120.217 108.450 137.013 1.00 46.03 ? 212 TYR B O   1 
ATOM   3322 C CB  . TYR B 2 212 ? 121.165 110.423 138.712 1.00 30.26 ? 212 TYR B CB  1 
ATOM   3323 C CG  . TYR B 2 212 ? 122.020 111.474 139.378 1.00 34.88 ? 212 TYR B CG  1 
ATOM   3324 C CD1 . TYR B 2 212 ? 121.963 111.676 140.748 1.00 37.72 ? 212 TYR B CD1 1 
ATOM   3325 C CD2 . TYR B 2 212 ? 122.891 112.259 138.639 1.00 41.53 ? 212 TYR B CD2 1 
ATOM   3326 C CE1 . TYR B 2 212 ? 122.743 112.632 141.361 1.00 38.89 ? 212 TYR B CE1 1 
ATOM   3327 C CE2 . TYR B 2 212 ? 123.677 113.216 139.244 1.00 42.29 ? 212 TYR B CE2 1 
ATOM   3328 C CZ  . TYR B 2 212 ? 123.599 113.398 140.605 1.00 39.91 ? 212 TYR B CZ  1 
ATOM   3329 O OH  . TYR B 2 212 ? 124.380 114.351 141.213 1.00 39.61 ? 212 TYR B OH  1 
ATOM   3330 N N   . PRO B 2 213 ? 120.825 106.780 138.394 1.00 35.88 ? 213 PRO B N   1 
ATOM   3331 C CA  . PRO B 2 213 ? 120.025 105.812 137.636 1.00 43.05 ? 213 PRO B CA  1 
ATOM   3332 C C   . PRO B 2 213 ? 118.551 105.830 138.007 1.00 46.03 ? 213 PRO B C   1 
ATOM   3333 O O   . PRO B 2 213 ? 118.207 105.886 139.191 1.00 53.11 ? 213 PRO B O   1 
ATOM   3334 C CB  . PRO B 2 213 ? 120.684 104.483 138.004 1.00 45.18 ? 213 PRO B CB  1 
ATOM   3335 C CG  . PRO B 2 213 ? 121.095 104.678 139.425 1.00 50.61 ? 213 PRO B CG  1 
ATOM   3336 C CD  . PRO B 2 213 ? 121.333 106.164 139.634 1.00 44.35 ? 213 PRO B CD  1 
ATOM   3337 N N   . HIS B 2 214 ? 117.681 105.786 136.998 1.00 36.00 ? 214 HIS B N   1 
ATOM   3338 C CA  . HIS B 2 214 ? 116.236 105.806 137.179 1.00 35.97 ? 214 HIS B CA  1 
ATOM   3339 C C   . HIS B 2 214 ? 115.589 104.770 136.274 1.00 40.65 ? 214 HIS B C   1 
ATOM   3340 O O   . HIS B 2 214 ? 116.156 104.379 135.251 1.00 51.25 ? 214 HIS B O   1 
ATOM   3341 C CB  . HIS B 2 214 ? 115.643 107.181 136.865 1.00 40.70 ? 214 HIS B CB  1 
ATOM   3342 C CG  . HIS B 2 214 ? 116.084 108.261 137.801 1.00 43.88 ? 214 HIS B CG  1 
ATOM   3343 N ND1 . HIS B 2 214 ? 115.504 108.457 139.035 1.00 44.09 ? 214 HIS B ND1 1 
ATOM   3344 C CD2 . HIS B 2 214 ? 117.038 109.213 137.678 1.00 42.77 ? 214 HIS B CD2 1 
ATOM   3345 C CE1 . HIS B 2 214 ? 116.088 109.478 139.636 1.00 45.36 ? 214 HIS B CE1 1 
ATOM   3346 N NE2 . HIS B 2 214 ? 117.021 109.954 138.834 1.00 44.64 ? 214 HIS B NE2 1 
ATOM   3347 N N   . PHE B 2 215 ? 114.396 104.331 136.668 1.00 46.83 ? 215 PHE B N   1 
ATOM   3348 C CA  . PHE B 2 215 ? 113.564 103.427 135.884 1.00 49.15 ? 215 PHE B CA  1 
ATOM   3349 C C   . PHE B 2 215 ? 112.304 104.162 135.458 1.00 52.40 ? 215 PHE B C   1 
ATOM   3350 O O   . PHE B 2 215 ? 111.648 104.802 136.286 1.00 58.19 ? 215 PHE B O   1 
ATOM   3351 C CB  . PHE B 2 215 ? 113.205 102.176 136.685 1.00 48.68 ? 215 PHE B CB  1 
ATOM   3352 C CG  . PHE B 2 215 ? 114.271 101.127 136.660 1.00 56.12 ? 215 PHE B CG  1 
ATOM   3353 C CD1 . PHE B 2 215 ? 114.419 100.302 135.559 1.00 53.96 ? 215 PHE B CD1 1 
ATOM   3354 C CD2 . PHE B 2 215 ? 115.134 100.970 137.730 1.00 56.21 ? 215 PHE B CD2 1 
ATOM   3355 C CE1 . PHE B 2 215 ? 115.401 99.343  135.529 1.00 50.89 ? 215 PHE B CE1 1 
ATOM   3356 C CE2 . PHE B 2 215 ? 116.117 100.010 137.703 1.00 49.81 ? 215 PHE B CE2 1 
ATOM   3357 C CZ  . PHE B 2 215 ? 116.247 99.196  136.602 1.00 49.60 ? 215 PHE B CZ  1 
ATOM   3358 N N   . THR B 2 216 ? 111.973 104.065 134.171 1.00 51.46 ? 216 THR B N   1 
ATOM   3359 C CA  . THR B 2 216 ? 110.931 104.870 133.549 1.00 54.47 ? 216 THR B CA  1 
ATOM   3360 C C   . THR B 2 216 ? 110.000 103.978 132.745 1.00 57.12 ? 216 THR B C   1 
ATOM   3361 O O   . THR B 2 216 ? 110.457 103.189 131.913 1.00 62.96 ? 216 THR B O   1 
ATOM   3362 C CB  . THR B 2 216 ? 111.548 105.923 132.627 1.00 57.78 ? 216 THR B CB  1 
ATOM   3363 O OG1 . THR B 2 216 ? 112.728 106.449 133.232 1.00 55.85 ? 216 THR B OG1 1 
ATOM   3364 C CG2 . THR B 2 216 ? 110.580 107.067 132.370 1.00 61.17 ? 216 THR B CG2 1 
ATOM   3365 N N   . CYS B 2 217 ? 108.700 104.110 132.988 1.00 61.75 ? 217 CYS B N   1 
ATOM   3366 C CA  . CYS B 2 217 ? 107.719 103.474 132.127 1.00 62.07 ? 217 CYS B CA  1 
ATOM   3367 C C   . CYS B 2 217 ? 107.633 104.224 130.802 1.00 62.02 ? 217 CYS B C   1 
ATOM   3368 O O   . CYS B 2 217 ? 108.217 105.296 130.627 1.00 61.94 ? 217 CYS B O   1 
ATOM   3369 C CB  . CYS B 2 217 ? 106.353 103.434 132.809 1.00 62.33 ? 217 CYS B CB  1 
ATOM   3370 S SG  . CYS B 2 217 ? 105.244 102.159 132.175 1.00 70.42 ? 217 CYS B SG  1 
ATOM   3371 N N   . ALA B 2 218 ? 106.910 103.635 129.848 1.00 65.72 ? 218 ALA B N   1 
ATOM   3372 C CA  . ALA B 2 218 ? 106.732 104.296 128.559 1.00 68.27 ? 218 ALA B CA  1 
ATOM   3373 C C   . ALA B 2 218 ? 105.967 105.605 128.715 1.00 66.63 ? 218 ALA B C   1 
ATOM   3374 O O   . ALA B 2 218 ? 106.225 106.572 127.989 1.00 60.48 ? 218 ALA B O   1 
ATOM   3375 C CB  . ALA B 2 218 ? 106.015 103.365 127.583 1.00 66.15 ? 218 ALA B CB  1 
ATOM   3376 N N   . VAL B 2 219 ? 105.014 105.645 129.646 1.00 74.83 ? 219 VAL B N   1 
ATOM   3377 C CA  . VAL B 2 219 ? 104.299 106.862 130.024 1.00 73.07 ? 219 VAL B CA  1 
ATOM   3378 C C   . VAL B 2 219 ? 104.434 107.038 131.531 1.00 69.24 ? 219 VAL B C   1 
ATOM   3379 O O   . VAL B 2 219 ? 103.962 106.199 132.309 1.00 68.70 ? 219 VAL B O   1 
ATOM   3380 C CB  . VAL B 2 219 ? 102.823 106.829 129.585 1.00 75.61 ? 219 VAL B CB  1 
ATOM   3381 C CG1 . VAL B 2 219 ? 102.717 107.093 128.092 1.00 73.73 ? 219 VAL B CG1 1 
ATOM   3382 C CG2 . VAL B 2 219 ? 102.134 105.493 129.926 1.00 70.85 ? 219 VAL B CG2 1 
ATOM   3383 N N   . ASP B 2 220 ? 105.107 108.128 131.922 1.00 71.86 ? 220 ASP B N   1 
ATOM   3384 C CA  . ASP B 2 220 ? 105.314 108.453 133.360 1.00 73.83 ? 220 ASP B CA  1 
ATOM   3385 C C   . ASP B 2 220 ? 105.075 109.956 133.527 1.00 75.28 ? 220 ASP B C   1 
ATOM   3386 O O   . ASP B 2 220 ? 105.709 110.736 132.784 1.00 77.34 ? 220 ASP B O   1 
ATOM   3387 C CB  . ASP B 2 220 ? 106.700 108.029 133.820 1.00 73.58 ? 220 ASP B CB  1 
ATOM   3388 C CG  . ASP B 2 220 ? 107.068 108.371 135.257 1.00 76.71 ? 220 ASP B CG  1 
ATOM   3389 O OD1 . ASP B 2 220 ? 106.202 108.903 135.984 1.00 77.22 ? 220 ASP B OD1 1 
ATOM   3390 O OD2 . ASP B 2 220 ? 108.228 108.109 135.636 1.00 74.05 ? 220 ASP B OD2 1 
ATOM   3391 N N   . THR B 2 221 ? 104.209 110.352 134.463 1.00 84.82 ? 221 THR B N   1 
ATOM   3392 C CA  . THR B 2 221 ? 103.862 111.760 134.628 1.00 85.16 ? 221 THR B CA  1 
ATOM   3393 C C   . THR B 2 221 ? 105.076 112.591 135.031 1.00 83.09 ? 221 THR B C   1 
ATOM   3394 O O   . THR B 2 221 ? 105.262 113.703 134.523 1.00 84.83 ? 221 THR B O   1 
ATOM   3395 C CB  . THR B 2 221 ? 102.735 111.907 135.651 1.00 85.29 ? 221 THR B CB  1 
ATOM   3396 O OG1 . THR B 2 221 ? 103.135 111.326 136.896 1.00 88.03 ? 221 THR B OG1 1 
ATOM   3397 C CG2 . THR B 2 221 ? 101.467 111.223 135.159 1.00 82.63 ? 221 THR B CG2 1 
ATOM   3398 N N   . GLU B 2 222 ? 105.921 112.063 135.921 1.00 69.55 ? 222 GLU B N   1 
ATOM   3399 C CA  . GLU B 2 222 ? 107.078 112.786 136.448 1.00 69.92 ? 222 GLU B CA  1 
ATOM   3400 C C   . GLU B 2 222 ? 108.367 112.150 135.952 1.00 69.84 ? 222 GLU B C   1 
ATOM   3401 O O   . GLU B 2 222 ? 108.808 111.128 136.489 1.00 72.40 ? 222 GLU B O   1 
ATOM   3402 C CB  . GLU B 2 222 ? 107.080 112.830 137.981 1.00 73.94 ? 222 GLU B CB  1 
ATOM   3403 C CG  . GLU B 2 222 ? 106.761 111.524 138.697 1.00 73.92 ? 222 GLU B CG  1 
ATOM   3404 C CD  . GLU B 2 222 ? 105.339 111.484 139.209 1.00 74.13 ? 222 GLU B CD  1 
ATOM   3405 O OE1 . GLU B 2 222 ? 105.142 111.187 140.406 1.00 72.22 ? 222 GLU B OE1 1 
ATOM   3406 O OE2 . GLU B 2 222 ? 104.419 111.777 138.424 1.00 77.19 ? 222 GLU B OE2 1 
ATOM   3407 N N   . ASN B 2 223 ? 108.965 112.763 134.929 1.00 59.40 ? 223 ASN B N   1 
ATOM   3408 C CA  . ASN B 2 223 ? 110.384 112.631 134.634 1.00 53.11 ? 223 ASN B CA  1 
ATOM   3409 C C   . ASN B 2 223 ? 111.119 113.957 134.734 1.00 50.43 ? 223 ASN B C   1 
ATOM   3410 O O   . ASN B 2 223 ? 112.319 113.961 135.037 1.00 51.82 ? 223 ASN B O   1 
ATOM   3411 C CB  . ASN B 2 223 ? 110.600 112.048 133.226 1.00 56.18 ? 223 ASN B CB  1 
ATOM   3412 C CG  . ASN B 2 223 ? 110.250 110.572 133.143 1.00 59.62 ? 223 ASN B CG  1 
ATOM   3413 O OD1 . ASN B 2 223 ? 110.680 109.774 133.976 1.00 58.49 ? 223 ASN B OD1 1 
ATOM   3414 N ND2 . ASN B 2 223 ? 109.481 110.199 132.128 1.00 55.30 ? 223 ASN B ND2 1 
ATOM   3415 N N   . ALA B 2 224 ? 110.428 115.078 134.511 1.00 51.07 ? 224 ALA B N   1 
ATOM   3416 C CA  . ALA B 2 224 ? 111.036 116.385 134.721 1.00 51.95 ? 224 ALA B CA  1 
ATOM   3417 C C   . ALA B 2 224 ? 111.359 116.614 136.191 1.00 54.13 ? 224 ALA B C   1 
ATOM   3418 O O   . ALA B 2 224 ? 112.349 117.272 136.517 1.00 55.62 ? 224 ALA B O   1 
ATOM   3419 C CB  . ALA B 2 224 ? 110.111 117.482 134.203 1.00 52.15 ? 224 ALA B CB  1 
ATOM   3420 N N   . ARG B 2 225 ? 110.524 116.094 137.092 1.00 57.30 ? 225 ARG B N   1 
ATOM   3421 C CA  . ARG B 2 225 ? 110.813 116.200 138.520 1.00 55.12 ? 225 ARG B CA  1 
ATOM   3422 C C   . ARG B 2 225 ? 112.103 115.472 138.871 1.00 55.75 ? 225 ARG B C   1 
ATOM   3423 O O   . ARG B 2 225 ? 112.934 115.986 139.633 1.00 54.52 ? 225 ARG B O   1 
ATOM   3424 C CB  . ARG B 2 225 ? 109.633 115.641 139.320 1.00 57.28 ? 225 ARG B CB  1 
ATOM   3425 C CG  . ARG B 2 225 ? 109.748 115.720 140.844 1.00 56.89 ? 225 ARG B CG  1 
ATOM   3426 C CD  . ARG B 2 225 ? 109.852 117.142 141.387 1.00 58.05 ? 225 ARG B CD  1 
ATOM   3427 N NE  . ARG B 2 225 ? 108.785 118.022 140.925 1.00 56.92 ? 225 ARG B NE  1 
ATOM   3428 C CZ  . ARG B 2 225 ? 108.672 119.308 141.238 1.00 58.01 ? 225 ARG B CZ  1 
ATOM   3429 N NH1 . ARG B 2 225 ? 109.550 119.918 142.022 1.00 58.08 ? 225 ARG B NH1 1 
ATOM   3430 N NH2 . ARG B 2 225 ? 107.646 120.003 140.757 1.00 58.47 ? 225 ARG B NH2 1 
ATOM   3431 N N   . ARG B 2 226 ? 112.292 114.276 138.314 1.00 53.98 ? 226 ARG B N   1 
ATOM   3432 C CA  . ARG B 2 226 ? 113.516 113.525 138.569 1.00 46.11 ? 226 ARG B CA  1 
ATOM   3433 C C   . ARG B 2 226 ? 114.720 114.248 137.982 1.00 46.01 ? 226 ARG B C   1 
ATOM   3434 O O   . ARG B 2 226 ? 115.764 114.364 138.636 1.00 49.00 ? 226 ARG B O   1 
ATOM   3435 C CB  . ARG B 2 226 ? 113.399 112.112 137.995 1.00 49.56 ? 226 ARG B CB  1 
ATOM   3436 C CG  . ARG B 2 226 ? 112.100 111.386 138.337 1.00 50.80 ? 226 ARG B CG  1 
ATOM   3437 C CD  . ARG B 2 226 ? 112.180 109.920 137.963 1.00 54.58 ? 226 ARG B CD  1 
ATOM   3438 N NE  . ARG B 2 226 ? 110.870 109.278 137.952 1.00 57.65 ? 226 ARG B NE  1 
ATOM   3439 C CZ  . ARG B 2 226 ? 110.663 107.970 137.860 1.00 55.36 ? 226 ARG B CZ  1 
ATOM   3440 N NH1 . ARG B 2 226 ? 111.666 107.107 137.781 1.00 52.23 ? 226 ARG B NH1 1 
ATOM   3441 N NH2 . ARG B 2 226 ? 109.415 107.513 137.844 1.00 55.86 ? 226 ARG B NH2 1 
ATOM   3442 N N   . ILE B 2 227 ? 114.581 114.770 136.758 1.00 47.74 ? 227 ILE B N   1 
ATOM   3443 C CA  . ILE B 2 227 ? 115.669 115.532 136.147 1.00 47.89 ? 227 ILE B CA  1 
ATOM   3444 C C   . ILE B 2 227 ? 116.017 116.734 137.014 1.00 44.89 ? 227 ILE B C   1 
ATOM   3445 O O   . ILE B 2 227 ? 117.194 117.030 137.246 1.00 43.61 ? 227 ILE B O   1 
ATOM   3446 C CB  . ILE B 2 227 ? 115.293 115.967 134.716 1.00 43.11 ? 227 ILE B CB  1 
ATOM   3447 C CG1 . ILE B 2 227 ? 115.192 114.760 133.782 1.00 44.60 ? 227 ILE B CG1 1 
ATOM   3448 C CG2 . ILE B 2 227 ? 116.326 116.955 134.173 1.00 46.67 ? 227 ILE B CG2 1 
ATOM   3449 C CD1 . ILE B 2 227 ? 114.371 115.007 132.536 1.00 48.71 ? 227 ILE B CD1 1 
ATOM   3450 N N   . PHE B 2 228 ? 115.000 117.422 137.533 1.00 48.18 ? 228 PHE B N   1 
ATOM   3451 C CA  . PHE B 2 228 ? 115.235 118.595 138.363 1.00 50.38 ? 228 PHE B CA  1 
ATOM   3452 C C   . PHE B 2 228 ? 115.940 118.232 139.661 1.00 46.93 ? 228 PHE B C   1 
ATOM   3453 O O   . PHE B 2 228 ? 116.830 118.964 140.102 1.00 50.50 ? 228 PHE B O   1 
ATOM   3454 C CB  . PHE B 2 228 ? 113.910 119.308 138.641 1.00 54.56 ? 228 PHE B CB  1 
ATOM   3455 C CG  . PHE B 2 228 ? 113.962 120.284 139.793 1.00 53.67 ? 228 PHE B CG  1 
ATOM   3456 C CD1 . PHE B 2 228 ? 114.861 121.338 139.794 1.00 53.62 ? 228 PHE B CD1 1 
ATOM   3457 C CD2 . PHE B 2 228 ? 113.083 120.168 140.856 1.00 49.61 ? 228 PHE B CD2 1 
ATOM   3458 C CE1 . PHE B 2 228 ? 114.906 122.230 140.847 1.00 50.35 ? 228 PHE B CE1 1 
ATOM   3459 C CE2 . PHE B 2 228 ? 113.121 121.063 141.909 1.00 47.62 ? 228 PHE B CE2 1 
ATOM   3460 C CZ  . PHE B 2 228 ? 114.033 122.096 141.901 1.00 48.47 ? 228 PHE B CZ  1 
ATOM   3461 N N   . ASN B 2 229 ? 115.558 117.127 140.308 1.00 40.08 ? 229 ASN B N   1 
ATOM   3462 C CA  . ASN B 2 229 ? 116.171 116.841 141.602 1.00 40.00 ? 229 ASN B CA  1 
ATOM   3463 C C   . ASN B 2 229 ? 117.612 116.352 141.430 1.00 43.13 ? 229 ASN B C   1 
ATOM   3464 O O   . ASN B 2 229 ? 118.483 116.682 142.246 1.00 51.04 ? 229 ASN B O   1 
ATOM   3465 C CB  . ASN B 2 229 ? 115.286 115.891 142.441 1.00 43.83 ? 229 ASN B CB  1 
ATOM   3466 C CG  . ASN B 2 229 ? 115.379 114.396 142.075 1.00 56.69 ? 229 ASN B CG  1 
ATOM   3467 O OD1 . ASN B 2 229 ? 116.088 113.959 141.179 1.00 61.27 ? 229 ASN B OD1 1 
ATOM   3468 N ND2 . ASN B 2 229 ? 114.625 113.601 142.821 1.00 51.81 ? 229 ASN B ND2 1 
ATOM   3469 N N   . ASP B 2 230 ? 117.904 115.609 140.350 1.00 36.48 ? 230 ASP B N   1 
ATOM   3470 C CA  . ASP B 2 230 ? 119.311 115.290 140.085 1.00 34.65 ? 230 ASP B CA  1 
ATOM   3471 C C   . ASP B 2 230 ? 120.105 116.530 139.681 1.00 39.84 ? 230 ASP B C   1 
ATOM   3472 O O   . ASP B 2 230 ? 121.295 116.635 139.994 1.00 36.10 ? 230 ASP B O   1 
ATOM   3473 C CB  . ASP B 2 230 ? 119.493 114.192 139.030 1.00 38.27 ? 230 ASP B CB  1 
ATOM   3474 C CG  . ASP B 2 230 ? 118.498 113.062 139.153 1.00 47.79 ? 230 ASP B CG  1 
ATOM   3475 O OD1 . ASP B 2 230 ? 118.533 112.348 140.176 1.00 52.57 ? 230 ASP B OD1 1 
ATOM   3476 O OD2 . ASP B 2 230 ? 117.780 112.790 138.173 1.00 46.91 ? 230 ASP B OD2 1 
ATOM   3477 N N   . CYS B 2 231 ? 119.478 117.478 138.982 1.00 46.67 ? 231 CYS B N   1 
ATOM   3478 C CA  . CYS B 2 231 ? 120.168 118.731 138.682 1.00 40.61 ? 231 CYS B CA  1 
ATOM   3479 C C   . CYS B 2 231 ? 120.450 119.525 139.952 1.00 44.50 ? 231 CYS B C   1 
ATOM   3480 O O   . CYS B 2 231 ? 121.513 120.143 140.083 1.00 49.62 ? 231 CYS B O   1 
ATOM   3481 C CB  . CYS B 2 231 ? 119.351 119.563 137.695 1.00 36.55 ? 231 CYS B CB  1 
ATOM   3482 S SG  . CYS B 2 231 ? 119.319 118.905 136.013 1.00 42.78 ? 231 CYS B SG  1 
ATOM   3483 N N   . LYS B 2 232 ? 119.507 119.527 140.896 1.00 46.12 ? 232 LYS B N   1 
ATOM   3484 C CA  . LYS B 2 232 ? 119.749 120.181 142.177 1.00 40.89 ? 232 LYS B CA  1 
ATOM   3485 C C   . LYS B 2 232 ? 120.882 119.495 142.925 1.00 36.20 ? 232 LYS B C   1 
ATOM   3486 O O   . LYS B 2 232 ? 121.710 120.163 143.548 1.00 38.04 ? 232 LYS B O   1 
ATOM   3487 C CB  . LYS B 2 232 ? 118.475 120.193 143.027 1.00 42.48 ? 232 LYS B CB  1 
ATOM   3488 C CG  . LYS B 2 232 ? 118.558 121.103 144.263 1.00 42.47 ? 232 LYS B CG  1 
ATOM   3489 C CD  . LYS B 2 232 ? 117.513 120.785 145.324 1.00 47.79 ? 232 LYS B CD  1 
ATOM   3490 C CE  . LYS B 2 232 ? 116.095 120.838 144.790 1.00 48.84 ? 232 LYS B CE  1 
ATOM   3491 N NZ  . LYS B 2 232 ? 115.109 120.789 145.904 1.00 45.69 ? 232 LYS B NZ  1 
ATOM   3492 N N   . ASP B 2 233 ? 120.929 118.162 142.883 1.00 28.46 ? 233 ASP B N   1 
ATOM   3493 C CA  . ASP B 2 233 ? 122.034 117.447 143.513 1.00 24.79 ? 233 ASP B CA  1 
ATOM   3494 C C   . ASP B 2 233 ? 123.362 117.806 142.855 1.00 37.37 ? 233 ASP B C   1 
ATOM   3495 O O   . ASP B 2 233 ? 124.365 118.016 143.544 1.00 51.07 ? 233 ASP B O   1 
ATOM   3496 C CB  . ASP B 2 233 ? 121.789 115.942 143.441 1.00 36.05 ? 233 ASP B CB  1 
ATOM   3497 C CG  . ASP B 2 233 ? 122.701 115.150 144.361 1.00 41.34 ? 233 ASP B CG  1 
ATOM   3498 O OD1 . ASP B 2 233 ? 123.662 115.721 144.915 1.00 43.67 ? 233 ASP B OD1 1 
ATOM   3499 O OD2 . ASP B 2 233 ? 122.455 113.938 144.530 1.00 44.71 ? 233 ASP B OD2 1 
ATOM   3500 N N   . ILE B 2 234 ? 123.384 117.885 141.522 1.00 38.96 ? 234 ILE B N   1 
ATOM   3501 C CA  . ILE B 2 234 ? 124.606 118.231 140.799 1.00 34.47 ? 234 ILE B CA  1 
ATOM   3502 C C   . ILE B 2 234 ? 125.075 119.623 141.198 1.00 36.38 ? 234 ILE B C   1 
ATOM   3503 O O   . ILE B 2 234 ? 126.265 119.850 141.466 1.00 37.24 ? 234 ILE B O   1 
ATOM   3504 C CB  . ILE B 2 234 ? 124.357 118.132 139.280 1.00 36.86 ? 234 ILE B CB  1 
ATOM   3505 C CG1 . ILE B 2 234 ? 124.255 116.668 138.847 1.00 39.14 ? 234 ILE B CG1 1 
ATOM   3506 C CG2 . ILE B 2 234 ? 125.466 118.832 138.485 1.00 36.50 ? 234 ILE B CG2 1 
ATOM   3507 C CD1 . ILE B 2 234 ? 123.508 116.468 137.552 1.00 33.98 ? 234 ILE B CD1 1 
ATOM   3508 N N   . ILE B 2 235 ? 124.145 120.577 141.241 1.00 41.95 ? 235 ILE B N   1 
ATOM   3509 C CA  . ILE B 2 235 ? 124.503 121.948 141.577 1.00 36.84 ? 235 ILE B CA  1 
ATOM   3510 C C   . ILE B 2 235 ? 124.960 122.035 143.027 1.00 35.96 ? 235 ILE B C   1 
ATOM   3511 O O   . ILE B 2 235 ? 125.899 122.769 143.355 1.00 46.82 ? 235 ILE B O   1 
ATOM   3512 C CB  . ILE B 2 235 ? 123.339 122.910 141.278 1.00 31.11 ? 235 ILE B CB  1 
ATOM   3513 C CG1 . ILE B 2 235 ? 123.053 122.941 139.769 1.00 31.95 ? 235 ILE B CG1 1 
ATOM   3514 C CG2 . ILE B 2 235 ? 123.663 124.307 141.804 1.00 42.12 ? 235 ILE B CG2 1 
ATOM   3515 C CD1 . ILE B 2 235 ? 121.722 123.527 139.393 1.00 39.58 ? 235 ILE B CD1 1 
ATOM   3516 N N   . LEU B 2 236 ? 124.309 121.279 143.913 1.00 26.75 ? 236 LEU B N   1 
ATOM   3517 C CA  . LEU B 2 236 ? 124.712 121.245 145.312 1.00 30.17 ? 236 LEU B CA  1 
ATOM   3518 C C   . LEU B 2 236 ? 126.139 120.744 145.447 1.00 33.30 ? 236 LEU B C   1 
ATOM   3519 O O   . LEU B 2 236 ? 126.943 121.333 146.171 1.00 45.66 ? 236 LEU B O   1 
ATOM   3520 C CB  . LEU B 2 236 ? 123.749 120.362 146.113 1.00 35.98 ? 236 LEU B CB  1 
ATOM   3521 C CG  . LEU B 2 236 ? 124.097 120.062 147.578 1.00 31.40 ? 236 LEU B CG  1 
ATOM   3522 C CD1 . LEU B 2 236 ? 122.855 120.143 148.451 1.00 30.16 ? 236 LEU B CD1 1 
ATOM   3523 C CD2 . LEU B 2 236 ? 124.758 118.701 147.745 1.00 36.04 ? 236 LEU B CD2 1 
ATOM   3524 N N   . GLN B 2 237 ? 126.478 119.662 144.745 1.00 29.69 ? 237 GLN B N   1 
ATOM   3525 C CA  . GLN B 2 237 ? 127.834 119.125 144.845 1.00 33.08 ? 237 GLN B CA  1 
ATOM   3526 C C   . GLN B 2 237 ? 128.877 120.080 144.275 1.00 39.59 ? 237 GLN B C   1 
ATOM   3527 O O   . GLN B 2 237 ? 129.966 120.226 144.853 1.00 45.08 ? 237 GLN B O   1 
ATOM   3528 C CB  . GLN B 2 237 ? 127.926 117.758 144.169 1.00 35.00 ? 237 GLN B CB  1 
ATOM   3529 C CG  . GLN B 2 237 ? 127.008 116.694 144.767 1.00 37.75 ? 237 GLN B CG  1 
ATOM   3530 C CD  . GLN B 2 237 ? 127.501 116.186 146.107 1.00 43.13 ? 237 GLN B CD  1 
ATOM   3531 O OE1 . GLN B 2 237 ? 128.696 116.223 146.400 1.00 47.37 ? 237 GLN B OE1 1 
ATOM   3532 N NE2 . GLN B 2 237 ? 126.576 115.719 146.935 1.00 40.10 ? 237 GLN B NE2 1 
ATOM   3533 N N   . MET B 2 238 ? 128.583 120.738 143.146 1.00 45.44 ? 238 MET B N   1 
ATOM   3534 C CA  . MET B 2 238 ? 129.562 121.695 142.630 1.00 40.17 ? 238 MET B CA  1 
ATOM   3535 C C   . MET B 2 238 ? 129.729 122.852 143.605 1.00 43.32 ? 238 MET B C   1 
ATOM   3536 O O   . MET B 2 238 ? 130.835 123.369 143.782 1.00 44.79 ? 238 MET B O   1 
ATOM   3537 C CB  . MET B 2 238 ? 129.189 122.199 141.225 1.00 37.80 ? 238 MET B CB  1 
ATOM   3538 C CG  . MET B 2 238 ? 128.156 123.335 141.076 1.00 42.21 ? 238 MET B CG  1 
ATOM   3539 S SD  . MET B 2 238 ? 128.142 124.081 139.430 1.00 59.56 ? 238 MET B SD  1 
ATOM   3540 C CE  . MET B 2 238 ? 128.107 122.649 138.358 1.00 43.65 ? 238 MET B CE  1 
ATOM   3541 N N   . ASN B 2 239 ? 128.634 123.274 144.245 1.00 44.44 ? 239 ASN B N   1 
ATOM   3542 C CA  . ASN B 2 239 ? 128.717 124.336 145.242 1.00 39.83 ? 239 ASN B CA  1 
ATOM   3543 C C   . ASN B 2 239 ? 129.531 123.907 146.459 1.00 40.83 ? 239 ASN B C   1 
ATOM   3544 O O   . ASN B 2 239 ? 130.301 124.705 147.005 1.00 51.35 ? 239 ASN B O   1 
ATOM   3545 C CB  . ASN B 2 239 ? 127.311 124.761 145.667 1.00 32.70 ? 239 ASN B CB  1 
ATOM   3546 C CG  . ASN B 2 239 ? 126.611 125.614 144.623 1.00 36.01 ? 239 ASN B CG  1 
ATOM   3547 O OD1 . ASN B 2 239 ? 127.217 126.046 143.644 1.00 37.70 ? 239 ASN B OD1 1 
ATOM   3548 N ND2 . ASN B 2 239 ? 125.325 125.863 144.831 1.00 35.84 ? 239 ASN B ND2 1 
ATOM   3549 N N   . LEU B 2 240 ? 129.368 122.659 146.911 1.00 35.32 ? 240 LEU B N   1 
ATOM   3550 C CA  . LEU B 2 240 ? 130.168 122.187 148.041 1.00 36.22 ? 240 LEU B CA  1 
ATOM   3551 C C   . LEU B 2 240 ? 131.646 122.142 147.686 1.00 36.91 ? 240 LEU B C   1 
ATOM   3552 O O   . LEU B 2 240 ? 132.497 122.473 148.517 1.00 51.19 ? 240 LEU B O   1 
ATOM   3553 C CB  . LEU B 2 240 ? 129.708 120.809 148.535 1.00 36.84 ? 240 LEU B CB  1 
ATOM   3554 C CG  . LEU B 2 240 ? 128.297 120.560 149.082 1.00 35.07 ? 240 LEU B CG  1 
ATOM   3555 C CD1 . LEU B 2 240 ? 128.220 119.178 149.698 1.00 34.08 ? 240 LEU B CD1 1 
ATOM   3556 C CD2 . LEU B 2 240 ? 127.896 121.607 150.102 1.00 42.36 ? 240 LEU B CD2 1 
ATOM   3557 N N   . ARG B 2 241 ? 131.978 121.727 146.462 1.00 41.61 ? 241 ARG B N   1 
ATOM   3558 C CA  . ARG B 2 241 ? 133.380 121.778 146.049 1.00 49.39 ? 241 ARG B CA  1 
ATOM   3559 C C   . ARG B 2 241 ? 133.875 123.218 145.943 1.00 48.40 ? 241 ARG B C   1 
ATOM   3560 O O   . ARG B 2 241 ? 135.023 123.516 146.292 1.00 41.82 ? 241 ARG B O   1 
ATOM   3561 C CB  . ARG B 2 241 ? 133.576 121.048 144.723 1.00 48.70 ? 241 ARG B CB  1 
ATOM   3562 C CG  . ARG B 2 241 ? 133.348 119.549 144.805 1.00 48.25 ? 241 ARG B CG  1 
ATOM   3563 C CD  . ARG B 2 241 ? 133.944 118.838 143.605 1.00 47.50 ? 241 ARG B CD  1 
ATOM   3564 N NE  . ARG B 2 241 ? 133.427 119.368 142.346 1.00 50.40 ? 241 ARG B NE  1 
ATOM   3565 C CZ  . ARG B 2 241 ? 132.378 118.901 141.677 1.00 53.17 ? 241 ARG B CZ  1 
ATOM   3566 N NH1 . ARG B 2 241 ? 131.651 117.887 142.125 1.00 50.42 ? 241 ARG B NH1 1 
ATOM   3567 N NH2 . ARG B 2 241 ? 132.041 119.473 140.525 1.00 48.45 ? 241 ARG B NH2 1 
ATOM   3568 N N   . GLU B 2 242 ? 133.024 124.122 145.452 1.00 49.62 ? 242 GLU B N   1 
ATOM   3569 C CA  . GLU B 2 242 ? 133.422 125.515 145.275 1.00 47.07 ? 242 GLU B CA  1 
ATOM   3570 C C   . GLU B 2 242 ? 133.699 126.190 146.612 1.00 52.05 ? 242 GLU B C   1 
ATOM   3571 O O   . GLU B 2 242 ? 134.672 126.940 146.748 1.00 57.50 ? 242 GLU B O   1 
ATOM   3572 C CB  . GLU B 2 242 ? 132.329 126.260 144.506 1.00 46.34 ? 242 GLU B CB  1 
ATOM   3573 C CG  . GLU B 2 242 ? 132.506 127.767 144.428 1.00 52.60 ? 242 GLU B CG  1 
ATOM   3574 C CD  . GLU B 2 242 ? 131.656 128.393 143.340 1.00 57.54 ? 242 GLU B CD  1 
ATOM   3575 O OE1 . GLU B 2 242 ? 132.227 129.025 142.427 1.00 58.02 ? 242 GLU B OE1 1 
ATOM   3576 O OE2 . GLU B 2 242 ? 130.417 128.252 143.398 1.00 54.68 ? 242 GLU B OE2 1 
ATOM   3577 N N   . TYR B 2 243 ? 132.851 125.937 147.611 1.00 51.34 ? 243 TYR B N   1 
ATOM   3578 C CA  . TYR B 2 243 ? 133.004 126.597 148.905 1.00 48.64 ? 243 TYR B CA  1 
ATOM   3579 C C   . TYR B 2 243 ? 134.100 125.959 149.758 1.00 50.00 ? 243 TYR B C   1 
ATOM   3580 O O   . TYR B 2 243 ? 134.340 126.407 150.885 1.00 53.16 ? 243 TYR B O   1 
ATOM   3581 C CB  . TYR B 2 243 ? 131.672 126.583 149.656 1.00 51.76 ? 243 TYR B CB  1 
ATOM   3582 C CG  . TYR B 2 243 ? 130.742 127.709 149.265 1.00 53.39 ? 243 TYR B CG  1 
ATOM   3583 C CD1 . TYR B 2 243 ? 131.001 129.014 149.660 1.00 52.42 ? 243 TYR B CD1 1 
ATOM   3584 C CD2 . TYR B 2 243 ? 129.607 127.468 148.505 1.00 49.96 ? 243 TYR B CD2 1 
ATOM   3585 C CE1 . TYR B 2 243 ? 130.162 130.046 149.308 1.00 49.50 ? 243 TYR B CE1 1 
ATOM   3586 C CE2 . TYR B 2 243 ? 128.759 128.497 148.147 1.00 52.82 ? 243 TYR B CE2 1 
ATOM   3587 C CZ  . TYR B 2 243 ? 129.042 129.784 148.553 1.00 54.70 ? 243 TYR B CZ  1 
ATOM   3588 O OH  . TYR B 2 243 ? 128.205 130.819 148.204 1.00 57.87 ? 243 TYR B OH  1 
ATOM   3589 N N   . ASN B 2 244 ? 134.739 124.888 149.267 1.00 52.26 ? 244 ASN B N   1 
ATOM   3590 C CA  . ASN B 2 244 ? 135.788 124.158 149.980 1.00 49.44 ? 244 ASN B CA  1 
ATOM   3591 C C   . ASN B 2 244 ? 135.238 123.405 151.189 1.00 49.06 ? 244 ASN B C   1 
ATOM   3592 O O   . ASN B 2 244 ? 136.012 122.965 152.045 1.00 51.04 ? 244 ASN B O   1 
ATOM   3593 C CB  . ASN B 2 244 ? 136.930 125.088 150.418 1.00 50.99 ? 244 ASN B CB  1 
ATOM   3594 C CG  . ASN B 2 244 ? 137.439 125.964 149.288 1.00 52.70 ? 244 ASN B CG  1 
ATOM   3595 O OD1 . ASN B 2 244 ? 137.969 125.467 148.296 1.00 54.06 ? 244 ASN B OD1 1 
ATOM   3596 N ND2 . ASN B 2 244 ? 137.285 127.275 149.435 1.00 45.98 ? 244 ASN B ND2 1 
ATOM   3597 N N   . LEU B 2 245 ? 133.913 123.253 151.282 1.00 46.23 ? 245 LEU B N   1 
ATOM   3598 C CA  . LEU B 2 245 ? 133.336 122.505 152.393 1.00 46.51 ? 245 LEU B CA  1 
ATOM   3599 C C   . LEU B 2 245 ? 133.701 121.030 152.309 1.00 47.25 ? 245 LEU B C   1 
ATOM   3600 O O   . LEU B 2 245 ? 134.167 120.441 153.292 1.00 52.02 ? 245 LEU B O   1 
ATOM   3601 C CB  . LEU B 2 245 ? 131.818 122.680 152.402 1.00 45.56 ? 245 LEU B CB  1 
ATOM   3602 C CG  . LEU B 2 245 ? 131.309 124.032 152.900 1.00 48.94 ? 245 LEU B CG  1 
ATOM   3603 C CD1 . LEU B 2 245 ? 129.903 124.280 152.388 1.00 47.10 ? 245 LEU B CD1 1 
ATOM   3604 C CD2 . LEU B 2 245 ? 131.351 124.114 154.419 1.00 50.98 ? 245 LEU B CD2 1 
ATOM   3605 N N   . VAL B 2 246 ? 133.484 120.416 151.149 1.00 53.68 ? 246 VAL B N   1 
ATOM   3606 C CA  . VAL B 2 246 ? 133.809 119.011 150.912 1.00 56.49 ? 246 VAL B CA  1 
ATOM   3607 C C   . VAL B 2 246 ? 134.335 118.870 149.490 1.00 53.60 ? 246 VAL B C   1 
ATOM   3608 O O   . VAL B 2 246 ? 133.622 118.437 148.587 1.00 49.61 ? 246 VAL B O   1 
ATOM   3609 C CB  . VAL B 2 246 ? 132.587 118.080 151.136 1.00 57.39 ? 246 VAL B CB  1 
ATOM   3610 C CG1 . VAL B 2 246 ? 132.974 116.619 150.879 1.00 53.98 ? 246 VAL B CG1 1 
ATOM   3611 C CG2 . VAL B 2 246 ? 132.007 118.252 152.547 1.00 55.56 ? 246 VAL B CG2 1 
ATOM   3612 O OXT . VAL B 2 246 ? 135.487 119.194 149.207 1.00 54.87 ? 246 VAL B OXT 1 
ATOM   3613 N N   . GLU C 3 28  ? 143.261 95.726  91.329  1.00 65.55 ? 10  GLU C N   1 
ATOM   3614 C CA  . GLU C 3 28  ? 143.538 96.967  90.616  1.00 67.62 ? 10  GLU C CA  1 
ATOM   3615 C C   . GLU C 3 28  ? 143.766 98.113  91.595  1.00 68.13 ? 10  GLU C C   1 
ATOM   3616 O O   . GLU C 3 28  ? 144.635 98.958  91.383  1.00 65.69 ? 10  GLU C O   1 
ATOM   3617 C CB  . GLU C 3 28  ? 142.389 97.308  89.666  1.00 63.05 ? 10  GLU C CB  1 
ATOM   3618 N N   . ALA C 3 29  ? 142.969 98.141  92.666  1.00 69.26 ? 11  ALA C N   1 
ATOM   3619 C CA  . ALA C 3 29  ? 143.124 99.186  93.673  1.00 69.78 ? 11  ALA C CA  1 
ATOM   3620 C C   . ALA C 3 29  ? 144.470 99.077  94.379  1.00 73.14 ? 11  ALA C C   1 
ATOM   3621 O O   . ALA C 3 29  ? 145.140 100.090 94.613  1.00 72.27 ? 11  ALA C O   1 
ATOM   3622 C CB  . ALA C 3 29  ? 141.982 99.111  94.685  1.00 67.45 ? 11  ALA C CB  1 
ATOM   3623 N N   . GLU C 3 30  ? 144.881 97.857  94.729  1.00 69.98 ? 12  GLU C N   1 
ATOM   3624 C CA  . GLU C 3 30  ? 146.146 97.678  95.435  1.00 68.18 ? 12  GLU C CA  1 
ATOM   3625 C C   . GLU C 3 30  ? 147.336 97.950  94.522  1.00 69.19 ? 12  GLU C C   1 
ATOM   3626 O O   . GLU C 3 30  ? 148.330 98.547  94.951  1.00 67.64 ? 12  GLU C O   1 
ATOM   3627 C CB  . GLU C 3 30  ? 146.227 96.265  96.010  1.00 61.04 ? 12  GLU C CB  1 
ATOM   3628 N N   . GLN C 3 31  ? 147.258 97.507  93.264  1.00 65.96 ? 13  GLN C N   1 
ATOM   3629 C CA  . GLN C 3 31  ? 148.386 97.659  92.349  1.00 65.48 ? 13  GLN C CA  1 
ATOM   3630 C C   . GLN C 3 31  ? 148.692 99.127  92.077  1.00 67.75 ? 13  GLN C C   1 
ATOM   3631 O O   . GLN C 3 31  ? 149.859 99.536  92.081  1.00 65.71 ? 13  GLN C O   1 
ATOM   3632 C CB  . GLN C 3 31  ? 148.099 96.924  91.040  1.00 60.22 ? 13  GLN C CB  1 
ATOM   3633 N N   . LEU C 3 32  ? 147.658 99.936  91.838  1.00 66.64 ? 14  LEU C N   1 
ATOM   3634 C CA  . LEU C 3 32  ? 147.885 101.355 91.576  1.00 64.72 ? 14  LEU C CA  1 
ATOM   3635 C C   . LEU C 3 32  ? 148.323 102.083 92.841  1.00 63.15 ? 14  LEU C C   1 
ATOM   3636 O O   . LEU C 3 32  ? 149.114 103.031 92.777  1.00 60.95 ? 14  LEU C O   1 
ATOM   3637 C CB  . LEU C 3 32  ? 146.627 102.005 90.994  1.00 65.09 ? 14  LEU C CB  1 
ATOM   3638 C CG  . LEU C 3 32  ? 146.678 102.355 89.505  1.00 66.35 ? 14  LEU C CG  1 
ATOM   3639 C CD1 . LEU C 3 32  ? 146.944 101.120 88.653  1.00 65.67 ? 14  LEU C CD1 1 
ATOM   3640 C CD2 . LEU C 3 32  ? 145.386 103.028 89.080  1.00 62.01 ? 14  LEU C CD2 1 
ATOM   3641 N N   . LYS C 3 33  ? 147.809 101.662 94.000  1.00 60.49 ? 15  LYS C N   1 
ATOM   3642 C CA  . LYS C 3 33  ? 148.239 102.264 95.259  1.00 62.66 ? 15  LYS C CA  1 
ATOM   3643 C C   . LYS C 3 33  ? 149.721 102.014 95.508  1.00 64.76 ? 15  LYS C C   1 
ATOM   3644 O O   . LYS C 3 33  ? 150.447 102.918 95.938  1.00 62.02 ? 15  LYS C O   1 
ATOM   3645 C CB  . LYS C 3 33  ? 147.403 101.715 96.414  1.00 60.12 ? 15  LYS C CB  1 
ATOM   3646 N N   . ASN C 3 34  ? 150.187 100.792 95.244  1.00 66.58 ? 16  ASN C N   1 
ATOM   3647 C CA  . ASN C 3 34  ? 151.615 100.508 95.352  1.00 63.92 ? 16  ASN C CA  1 
ATOM   3648 C C   . ASN C 3 34  ? 152.406 101.282 94.305  1.00 65.20 ? 16  ASN C C   1 
ATOM   3649 O O   . ASN C 3 34  ? 153.537 101.710 94.563  1.00 64.50 ? 16  ASN C O   1 
ATOM   3650 C CB  . ASN C 3 34  ? 151.864 99.007  95.213  1.00 60.55 ? 16  ASN C CB  1 
ATOM   3651 N N   . GLN C 3 35  ? 151.833 101.457 93.111  1.00 65.07 ? 17  GLN C N   1 
ATOM   3652 C CA  . GLN C 3 35  ? 152.501 102.242 92.078  1.00 64.46 ? 17  GLN C CA  1 
ATOM   3653 C C   . GLN C 3 35  ? 152.659 103.694 92.513  1.00 65.04 ? 17  GLN C C   1 
ATOM   3654 O O   . GLN C 3 35  ? 153.698 104.315 92.262  1.00 62.87 ? 17  GLN C O   1 
ATOM   3655 C CB  . GLN C 3 35  ? 151.720 102.149 90.765  1.00 63.58 ? 17  GLN C CB  1 
ATOM   3656 C CG  . GLN C 3 35  ? 152.290 102.981 89.619  1.00 64.11 ? 17  GLN C CG  1 
ATOM   3657 C CD  . GLN C 3 35  ? 151.521 104.269 89.376  1.00 66.28 ? 17  GLN C CD  1 
ATOM   3658 O OE1 . GLN C 3 35  ? 151.038 104.907 90.311  1.00 65.61 ? 17  GLN C OE1 1 
ATOM   3659 N NE2 . GLN C 3 35  ? 151.406 104.657 88.111  1.00 65.38 ? 17  GLN C NE2 1 
ATOM   3660 N N   . ILE C 3 36  ? 151.634 104.254 93.160  1.00 62.61 ? 18  ILE C N   1 
ATOM   3661 C CA  . ILE C 3 36  ? 151.739 105.613 93.686  1.00 62.04 ? 18  ILE C CA  1 
ATOM   3662 C C   . ILE C 3 36  ? 152.799 105.673 94.778  1.00 60.99 ? 18  ILE C C   1 
ATOM   3663 O O   . ILE C 3 36  ? 153.535 106.660 94.894  1.00 60.62 ? 18  ILE C O   1 
ATOM   3664 C CB  . ILE C 3 36  ? 150.368 106.102 94.192  1.00 63.63 ? 18  ILE C CB  1 
ATOM   3665 C CG1 . ILE C 3 36  ? 149.412 106.338 93.020  1.00 61.58 ? 18  ILE C CG1 1 
ATOM   3666 C CG2 . ILE C 3 36  ? 150.511 107.392 95.000  1.00 60.47 ? 18  ILE C CG2 1 
ATOM   3667 C CD1 . ILE C 3 36  ? 147.948 106.227 93.389  1.00 60.61 ? 18  ILE C CD1 1 
ATOM   3668 N N   . ARG C 3 37  ? 152.882 104.627 95.605  1.00 64.17 ? 19  ARG C N   1 
ATOM   3669 C CA  . ARG C 3 37  ? 153.924 104.574 96.625  1.00 64.26 ? 19  ARG C CA  1 
ATOM   3670 C C   . ARG C 3 37  ? 155.308 104.546 95.990  1.00 65.22 ? 19  ARG C C   1 
ATOM   3671 O O   . ARG C 3 37  ? 156.239 105.196 96.480  1.00 63.80 ? 19  ARG C O   1 
ATOM   3672 C CB  . ARG C 3 37  ? 153.723 103.350 97.519  1.00 61.60 ? 19  ARG C CB  1 
ATOM   3673 N N   . ASP C 3 38  ? 155.464 103.792 94.901  1.00 63.45 ? 20  ASP C N   1 
ATOM   3674 C CA  . ASP C 3 38  ? 156.737 103.773 94.189  1.00 63.39 ? 20  ASP C CA  1 
ATOM   3675 C C   . ASP C 3 38  ? 157.041 105.129 93.563  1.00 65.10 ? 20  ASP C C   1 
ATOM   3676 O O   . ASP C 3 38  ? 158.194 105.575 93.564  1.00 60.39 ? 20  ASP C O   1 
ATOM   3677 C CB  . ASP C 3 38  ? 156.719 102.682 93.118  1.00 60.59 ? 20  ASP C CB  1 
ATOM   3678 N N   . ALA C 3 39  ? 156.020 105.792 93.011  1.00 67.49 ? 21  ALA C N   1 
ATOM   3679 C CA  . ALA C 3 39  ? 156.241 107.068 92.337  1.00 60.72 ? 21  ALA C CA  1 
ATOM   3680 C C   . ALA C 3 39  ? 156.717 108.137 93.311  1.00 62.66 ? 21  ALA C C   1 
ATOM   3681 O O   . ALA C 3 39  ? 157.665 108.874 93.019  1.00 67.08 ? 21  ALA C O   1 
ATOM   3682 C CB  . ALA C 3 39  ? 154.961 107.520 91.637  1.00 59.41 ? 21  ALA C CB  1 
ATOM   3683 N N   . ARG C 3 40  ? 156.074 108.240 94.476  1.00 62.77 ? 22  ARG C N   1 
ATOM   3684 C CA  . ARG C 3 40  ? 156.517 109.213 95.468  1.00 62.17 ? 22  ARG C CA  1 
ATOM   3685 C C   . ARG C 3 40  ? 157.865 108.814 96.060  1.00 61.46 ? 22  ARG C C   1 
ATOM   3686 O O   . ARG C 3 40  ? 158.700 109.676 96.357  1.00 61.86 ? 22  ARG C O   1 
ATOM   3687 C CB  . ARG C 3 40  ? 155.452 109.376 96.558  1.00 60.41 ? 22  ARG C CB  1 
ATOM   3688 C CG  . ARG C 3 40  ? 155.218 108.160 97.456  1.00 62.67 ? 22  ARG C CG  1 
ATOM   3689 C CD  . ARG C 3 40  ? 154.190 108.426 98.558  1.00 65.53 ? 22  ARG C CD  1 
ATOM   3690 N NE  . ARG C 3 40  ? 152.816 108.534 98.071  1.00 65.92 ? 22  ARG C NE  1 
ATOM   3691 C CZ  . ARG C 3 40  ? 152.216 109.646 97.658  1.00 63.21 ? 22  ARG C CZ  1 
ATOM   3692 N NH1 . ARG C 3 40  ? 152.842 110.812 97.625  1.00 63.76 ? 22  ARG C NH1 1 
ATOM   3693 N NH2 . ARG C 3 40  ? 150.945 109.589 97.274  1.00 59.48 ? 22  ARG C NH2 1 
ATOM   3694 N N   . LYS C 3 41  ? 158.095 107.511 96.237  1.00 60.70 ? 23  LYS C N   1 
ATOM   3695 C CA  . LYS C 3 41  ? 159.367 107.046 96.778  1.00 62.28 ? 23  LYS C CA  1 
ATOM   3696 C C   . LYS C 3 41  ? 160.509 107.228 95.788  1.00 63.72 ? 23  LYS C C   1 
ATOM   3697 O O   . LYS C 3 41  ? 161.656 107.424 96.202  1.00 64.12 ? 23  LYS C O   1 
ATOM   3698 C CB  . LYS C 3 41  ? 159.260 105.575 97.181  1.00 61.27 ? 23  LYS C CB  1 
ATOM   3699 N N   . ALA C 3 42  ? 160.221 107.156 94.487  1.00 65.54 ? 24  ALA C N   1 
ATOM   3700 C CA  . ALA C 3 42  ? 161.255 107.401 93.487  1.00 64.09 ? 24  ALA C CA  1 
ATOM   3701 C C   . ALA C 3 42  ? 161.750 108.839 93.554  1.00 62.85 ? 24  ALA C C   1 
ATOM   3702 O O   . ALA C 3 42  ? 162.936 109.108 93.331  1.00 62.18 ? 24  ALA C O   1 
ATOM   3703 C CB  . ALA C 3 42  ? 160.717 107.085 92.092  1.00 60.71 ? 24  ALA C CB  1 
ATOM   3704 N N   . CYS C 3 43  ? 160.852 109.779 93.854  1.00 63.85 ? 25  CYS C N   1 
ATOM   3705 C CA  . CYS C 3 43  ? 161.231 111.187 93.894  1.00 63.56 ? 25  CYS C CA  1 
ATOM   3706 C C   . CYS C 3 43  ? 162.093 111.509 95.111  1.00 64.07 ? 25  CYS C C   1 
ATOM   3707 O O   . CYS C 3 43  ? 162.882 112.460 95.083  1.00 66.33 ? 25  CYS C O   1 
ATOM   3708 C CB  . CYS C 3 43  ? 159.977 112.060 93.884  1.00 57.62 ? 25  CYS C CB  1 
ATOM   3709 S SG  . CYS C 3 43  ? 159.276 112.319 92.242  1.00 63.92 ? 25  CYS C SG  1 
ATOM   3710 N N   . ALA C 3 44  ? 161.965 110.731 96.189  1.00 59.72 ? 26  ALA C N   1 
ATOM   3711 C CA  . ALA C 3 44  ? 162.570 111.078 97.476  1.00 60.50 ? 26  ALA C CA  1 
ATOM   3712 C C   . ALA C 3 44  ? 164.081 110.844 97.434  1.00 66.56 ? 26  ALA C C   1 
ATOM   3713 O O   . ALA C 3 44  ? 164.624 109.907 98.024  1.00 69.26 ? 26  ALA C O   1 
ATOM   3714 C CB  . ALA C 3 44  ? 161.920 110.277 98.595  1.00 56.79 ? 26  ALA C CB  1 
ATOM   3715 N N   . ASP C 3 45  ? 164.768 111.735 96.714  1.00 68.18 ? 27  ASP C N   1 
ATOM   3716 C CA  . ASP C 3 45  ? 166.229 111.696 96.692  1.00 66.98 ? 27  ASP C CA  1 
ATOM   3717 C C   . ASP C 3 45  ? 166.822 112.246 97.986  1.00 67.00 ? 27  ASP C C   1 
ATOM   3718 O O   . ASP C 3 45  ? 167.848 111.747 98.464  1.00 68.68 ? 27  ASP C O   1 
ATOM   3719 C CB  . ASP C 3 45  ? 166.777 112.453 95.472  1.00 68.12 ? 27  ASP C CB  1 
ATOM   3720 C CG  . ASP C 3 45  ? 166.281 113.894 95.372  1.00 69.96 ? 27  ASP C CG  1 
ATOM   3721 O OD1 . ASP C 3 45  ? 166.264 114.617 96.387  1.00 67.97 ? 27  ASP C OD1 1 
ATOM   3722 O OD2 . ASP C 3 45  ? 165.907 114.305 94.253  1.00 69.27 ? 27  ASP C OD2 1 
ATOM   3723 N N   . ALA C 3 46  ? 166.199 113.278 98.559  1.00 61.48 ? 28  ALA C N   1 
ATOM   3724 C CA  . ALA C 3 46  ? 166.707 113.954 99.745  1.00 61.74 ? 28  ALA C CA  1 
ATOM   3725 C C   . ALA C 3 46  ? 165.555 114.320 100.667 1.00 59.88 ? 28  ALA C C   1 
ATOM   3726 O O   . ALA C 3 46  ? 164.401 114.401 100.241 1.00 59.57 ? 28  ALA C O   1 
ATOM   3727 C CB  . ALA C 3 46  ? 167.490 115.221 99.379  1.00 60.00 ? 28  ALA C CB  1 
ATOM   3728 N N   . THR C 3 47  ? 165.881 114.505 101.944 1.00 55.88 ? 29  THR C N   1 
ATOM   3729 C CA  . THR C 3 47  ? 164.944 115.053 102.911 1.00 59.94 ? 29  THR C CA  1 
ATOM   3730 C C   . THR C 3 47  ? 165.022 116.578 102.896 1.00 56.19 ? 29  THR C C   1 
ATOM   3731 O O   . THR C 3 47  ? 166.013 117.168 102.458 1.00 59.24 ? 29  THR C O   1 
ATOM   3732 C CB  . THR C 3 47  ? 165.261 114.522 104.312 1.00 57.41 ? 29  THR C CB  1 
ATOM   3733 O OG1 . THR C 3 47  ? 165.727 113.172 104.214 1.00 56.25 ? 29  THR C OG1 1 
ATOM   3734 C CG2 . THR C 3 47  ? 164.029 114.550 105.209 1.00 56.05 ? 29  THR C CG2 1 
ATOM   3735 N N   . LEU C 3 48  ? 163.959 117.227 103.378 1.00 39.51 ? 30  LEU C N   1 
ATOM   3736 C CA  . LEU C 3 48  ? 164.041 118.669 103.593 1.00 41.67 ? 30  LEU C CA  1 
ATOM   3737 C C   . LEU C 3 48  ? 165.049 118.992 104.687 1.00 48.93 ? 30  LEU C C   1 
ATOM   3738 O O   . LEU C 3 48  ? 165.666 120.062 104.674 1.00 52.99 ? 30  LEU C O   1 
ATOM   3739 C CB  . LEU C 3 48  ? 162.664 119.249 103.936 1.00 47.93 ? 30  LEU C CB  1 
ATOM   3740 C CG  . LEU C 3 48  ? 162.581 120.734 104.343 1.00 46.49 ? 30  LEU C CG  1 
ATOM   3741 C CD1 . LEU C 3 48  ? 163.128 121.664 103.268 1.00 49.12 ? 30  LEU C CD1 1 
ATOM   3742 C CD2 . LEU C 3 48  ? 161.152 121.117 104.661 1.00 41.97 ? 30  LEU C CD2 1 
ATOM   3743 N N   . SER C 3 49  ? 165.212 118.088 105.658 1.00 54.90 ? 31  SER C N   1 
ATOM   3744 C CA  . SER C 3 49  ? 166.185 118.313 106.723 1.00 55.61 ? 31  SER C CA  1 
ATOM   3745 C C   . SER C 3 49  ? 167.604 118.387 106.172 1.00 55.99 ? 31  SER C C   1 
ATOM   3746 O O   . SER C 3 49  ? 168.431 119.160 106.670 1.00 53.62 ? 31  SER C O   1 
ATOM   3747 C CB  . SER C 3 49  ? 166.082 117.211 107.775 1.00 53.75 ? 31  SER C CB  1 
ATOM   3748 O OG  . SER C 3 49  ? 164.888 117.337 108.528 1.00 50.67 ? 31  SER C OG  1 
ATOM   3749 N N   . GLN C 3 50  ? 167.914 117.580 105.157 1.00 54.94 ? 32  GLN C N   1 
ATOM   3750 C CA  . GLN C 3 50  ? 169.247 117.632 104.567 1.00 53.58 ? 32  GLN C CA  1 
ATOM   3751 C C   . GLN C 3 50  ? 169.485 118.955 103.850 1.00 57.71 ? 32  GLN C C   1 
ATOM   3752 O O   . GLN C 3 50  ? 170.542 119.575 104.011 1.00 61.31 ? 32  GLN C O   1 
ATOM   3753 C CB  . GLN C 3 50  ? 169.447 116.461 103.607 1.00 56.14 ? 32  GLN C CB  1 
ATOM   3754 C CG  . GLN C 3 50  ? 169.817 115.157 104.294 1.00 59.52 ? 32  GLN C CG  1 
ATOM   3755 C CD  . GLN C 3 50  ? 169.813 113.975 103.344 1.00 62.66 ? 32  GLN C CD  1 
ATOM   3756 O OE1 . GLN C 3 50  ? 169.020 113.045 103.493 1.00 60.45 ? 32  GLN C OE1 1 
ATOM   3757 N NE2 . GLN C 3 50  ? 170.706 114.004 102.362 1.00 60.19 ? 32  GLN C NE2 1 
ATOM   3758 N N   . ILE C 3 51  ? 168.510 119.406 103.056 1.00 52.30 ? 33  ILE C N   1 
ATOM   3759 C CA  . ILE C 3 51  ? 168.681 120.638 102.289 1.00 52.99 ? 33  ILE C CA  1 
ATOM   3760 C C   . ILE C 3 51  ? 168.733 121.845 103.219 1.00 57.96 ? 33  ILE C C   1 
ATOM   3761 O O   . ILE C 3 51  ? 169.523 122.774 103.014 1.00 58.83 ? 33  ILE C O   1 
ATOM   3762 C CB  . ILE C 3 51  ? 167.558 120.782 101.239 1.00 48.98 ? 33  ILE C CB  1 
ATOM   3763 C CG1 . ILE C 3 51  ? 167.523 119.594 100.259 1.00 54.32 ? 33  ILE C CG1 1 
ATOM   3764 C CG2 . ILE C 3 51  ? 167.701 122.093 100.480 1.00 51.16 ? 33  ILE C CG2 1 
ATOM   3765 C CD1 . ILE C 3 51  ? 168.632 119.599 99.213  1.00 57.68 ? 33  ILE C CD1 1 
ATOM   3766 N N   . THR C 3 52  ? 167.894 121.847 104.256 1.00 53.48 ? 34  THR C N   1 
ATOM   3767 C CA  . THR C 3 52  ? 167.792 122.999 105.148 1.00 52.12 ? 34  THR C CA  1 
ATOM   3768 C C   . THR C 3 52  ? 168.917 123.036 106.183 1.00 52.26 ? 34  THR C C   1 
ATOM   3769 O O   . THR C 3 52  ? 168.999 123.985 106.971 1.00 53.90 ? 34  THR C O   1 
ATOM   3770 C CB  . THR C 3 52  ? 166.430 122.980 105.843 1.00 50.16 ? 34  THR C CB  1 
ATOM   3771 O OG1 . THR C 3 52  ? 166.131 124.280 106.364 1.00 49.99 ? 34  THR C OG1 1 
ATOM   3772 C CG2 . THR C 3 52  ? 166.403 121.941 106.965 1.00 53.00 ? 34  THR C CG2 1 
ATOM   3773 N N   . ASN C 3 53  ? 169.773 122.003 106.217 1.00 60.39 ? 35  ASN C N   1 
ATOM   3774 C CA  . ASN C 3 53  ? 170.672 121.798 107.353 1.00 64.03 ? 35  ASN C CA  1 
ATOM   3775 C C   . ASN C 3 53  ? 171.659 122.947 107.528 1.00 66.54 ? 35  ASN C C   1 
ATOM   3776 O O   . ASN C 3 53  ? 171.960 123.339 108.662 1.00 62.98 ? 35  ASN C O   1 
ATOM   3777 C CB  . ASN C 3 53  ? 171.425 120.479 107.185 1.00 60.45 ? 35  ASN C CB  1 
ATOM   3778 N N   . ASN C 3 54  ? 172.170 123.501 106.424 1.00 71.78 ? 36  ASN C N   1 
ATOM   3779 C CA  . ASN C 3 54  ? 173.180 124.569 106.479 1.00 69.58 ? 36  ASN C CA  1 
ATOM   3780 C C   . ASN C 3 54  ? 172.495 125.910 106.207 1.00 69.06 ? 36  ASN C C   1 
ATOM   3781 O O   . ASN C 3 54  ? 172.698 126.564 105.182 1.00 72.36 ? 36  ASN C O   1 
ATOM   3782 C CB  . ASN C 3 54  ? 174.338 124.320 105.514 1.00 71.54 ? 36  ASN C CB  1 
ATOM   3783 C CG  . ASN C 3 54  ? 173.902 123.756 104.171 1.00 75.99 ? 36  ASN C CG  1 
ATOM   3784 O OD1 . ASN C 3 54  ? 173.097 124.361 103.464 1.00 76.06 ? 36  ASN C OD1 1 
ATOM   3785 N ND2 . ASN C 3 54  ? 174.437 122.593 103.814 1.00 74.77 ? 36  ASN C ND2 1 
ATOM   3786 N N   . ILE C 3 55  ? 171.659 126.310 107.164 1.00 51.88 ? 37  ILE C N   1 
ATOM   3787 C CA  . ILE C 3 55  ? 170.981 127.600 107.149 1.00 51.68 ? 37  ILE C CA  1 
ATOM   3788 C C   . ILE C 3 55  ? 171.026 128.140 108.571 1.00 51.43 ? 37  ILE C C   1 
ATOM   3789 O O   . ILE C 3 55  ? 170.996 127.381 109.544 1.00 49.64 ? 37  ILE C O   1 
ATOM   3790 C CB  . ILE C 3 55  ? 169.529 127.469 106.598 1.00 53.51 ? 37  ILE C CB  1 
ATOM   3791 C CG1 . ILE C 3 55  ? 169.520 127.643 105.066 1.00 52.92 ? 37  ILE C CG1 1 
ATOM   3792 C CG2 . ILE C 3 55  ? 168.507 128.407 107.299 1.00 50.62 ? 37  ILE C CG2 1 
ATOM   3793 C CD1 . ILE C 3 55  ? 169.744 129.073 104.514 1.00 50.93 ? 37  ILE C CD1 1 
ATOM   3794 N N   . ASP C 3 56  ? 171.130 129.459 108.692 1.00 48.51 ? 38  ASP C N   1 
ATOM   3795 C CA  . ASP C 3 56  ? 171.131 130.068 110.010 1.00 50.34 ? 38  ASP C CA  1 
ATOM   3796 C C   . ASP C 3 56  ? 169.743 129.929 110.641 1.00 49.90 ? 38  ASP C C   1 
ATOM   3797 O O   . ASP C 3 56  ? 168.736 130.162 109.965 1.00 47.48 ? 38  ASP C O   1 
ATOM   3798 C CB  . ASP C 3 56  ? 171.517 131.544 109.920 1.00 46.42 ? 38  ASP C CB  1 
ATOM   3799 N N   . PRO C 3 57  ? 169.641 129.554 111.921 1.00 46.14 ? 39  PRO C N   1 
ATOM   3800 C CA  . PRO C 3 57  ? 168.310 129.414 112.519 1.00 43.63 ? 39  PRO C CA  1 
ATOM   3801 C C   . PRO C 3 57  ? 167.651 130.765 112.744 1.00 46.59 ? 39  PRO C C   1 
ATOM   3802 O O   . PRO C 3 57  ? 168.314 131.800 112.840 1.00 42.90 ? 39  PRO C O   1 
ATOM   3803 C CB  . PRO C 3 57  ? 168.592 128.704 113.845 1.00 38.67 ? 39  PRO C CB  1 
ATOM   3804 C CG  . PRO C 3 57  ? 169.932 129.175 114.209 1.00 44.84 ? 39  PRO C CG  1 
ATOM   3805 C CD  . PRO C 3 57  ? 170.687 129.236 112.915 1.00 44.44 ? 39  PRO C CD  1 
ATOM   3806 N N   . VAL C 3 58  ? 166.319 130.743 112.823 1.00 45.83 ? 40  VAL C N   1 
ATOM   3807 C CA  . VAL C 3 58  ? 165.574 131.967 113.107 1.00 39.15 ? 40  VAL C CA  1 
ATOM   3808 C C   . VAL C 3 58  ? 165.887 132.468 114.512 1.00 43.68 ? 40  VAL C C   1 
ATOM   3809 O O   . VAL C 3 58  ? 165.821 133.673 114.784 1.00 42.35 ? 40  VAL C O   1 
ATOM   3810 C CB  . VAL C 3 58  ? 164.061 131.743 112.913 1.00 35.97 ? 40  VAL C CB  1 
ATOM   3811 C CG1 . VAL C 3 58  ? 163.771 131.198 111.527 1.00 41.06 ? 40  VAL C CG1 1 
ATOM   3812 C CG2 . VAL C 3 58  ? 163.494 130.823 113.988 1.00 38.45 ? 40  VAL C CG2 1 
ATOM   3813 N N   . GLY C 3 59  ? 166.215 131.555 115.428 1.00 50.24 ? 41  GLY C N   1 
ATOM   3814 C CA  . GLY C 3 59  ? 166.493 131.918 116.801 1.00 51.22 ? 41  GLY C CA  1 
ATOM   3815 C C   . GLY C 3 59  ? 165.227 131.980 117.622 1.00 48.17 ? 41  GLY C C   1 
ATOM   3816 O O   . GLY C 3 59  ? 164.114 131.749 117.144 1.00 49.32 ? 41  GLY C O   1 
ATOM   3817 N N   . ARG C 3 60  ? 165.402 132.292 118.902 1.00 53.11 ? 42  ARG C N   1 
ATOM   3818 C CA  . ARG C 3 60  ? 164.252 132.410 119.783 1.00 51.50 ? 42  ARG C CA  1 
ATOM   3819 C C   . ARG C 3 60  ? 163.421 133.616 119.362 1.00 52.36 ? 42  ARG C C   1 
ATOM   3820 O O   . ARG C 3 60  ? 163.941 134.726 119.217 1.00 57.04 ? 42  ARG C O   1 
ATOM   3821 C CB  . ARG C 3 60  ? 164.715 132.543 121.239 1.00 53.70 ? 42  ARG C CB  1 
ATOM   3822 C CG  . ARG C 3 60  ? 163.594 132.573 122.301 1.00 50.43 ? 42  ARG C CG  1 
ATOM   3823 C CD  . ARG C 3 60  ? 164.042 133.200 123.621 1.00 53.03 ? 42  ARG C CD  1 
ATOM   3824 N NE  . ARG C 3 60  ? 162.927 133.839 124.316 1.00 57.54 ? 42  ARG C NE  1 
ATOM   3825 C CZ  . ARG C 3 60  ? 162.640 135.137 124.313 1.00 56.71 ? 42  ARG C CZ  1 
ATOM   3826 N NH1 . ARG C 3 60  ? 163.319 136.007 123.577 1.00 57.25 ? 42  ARG C NH1 1 
ATOM   3827 N NH2 . ARG C 3 60  ? 161.632 135.577 125.060 1.00 53.65 ? 42  ARG C NH2 1 
ATOM   3828 N N   . ILE C 3 61  ? 162.124 133.387 119.164 1.00 42.55 ? 43  ILE C N   1 
ATOM   3829 C CA  . ILE C 3 61  ? 161.171 134.425 118.786 1.00 43.40 ? 43  ILE C CA  1 
ATOM   3830 C C   . ILE C 3 61  ? 160.253 134.665 119.976 1.00 42.70 ? 43  ILE C C   1 
ATOM   3831 O O   . ILE C 3 61  ? 159.649 133.725 120.504 1.00 45.11 ? 43  ILE C O   1 
ATOM   3832 C CB  . ILE C 3 61  ? 160.377 134.053 117.513 1.00 38.65 ? 43  ILE C CB  1 
ATOM   3833 C CG1 . ILE C 3 61  ? 159.481 132.824 117.707 1.00 36.13 ? 43  ILE C CG1 1 
ATOM   3834 C CG2 . ILE C 3 61  ? 161.326 133.801 116.357 1.00 36.86 ? 43  ILE C CG2 1 
ATOM   3835 C CD1 . ILE C 3 61  ? 158.023 133.152 117.967 1.00 33.29 ? 43  ILE C CD1 1 
ATOM   3836 N N   . GLN C 3 62  ? 160.179 135.921 120.410 1.00 40.59 ? 44  GLN C N   1 
ATOM   3837 C CA  . GLN C 3 62  ? 159.413 136.327 121.579 1.00 41.03 ? 44  GLN C CA  1 
ATOM   3838 C C   . GLN C 3 62  ? 158.298 137.261 121.141 1.00 39.09 ? 44  GLN C C   1 
ATOM   3839 O O   . GLN C 3 62  ? 158.561 138.307 120.536 1.00 37.47 ? 44  GLN C O   1 
ATOM   3840 C CB  . GLN C 3 62  ? 160.307 137.020 122.606 1.00 39.51 ? 44  GLN C CB  1 
ATOM   3841 N N   . MET C 3 63  ? 157.063 136.878 121.451 1.00 31.20 ? 45  MET C N   1 
ATOM   3842 C CA  . MET C 3 63  ? 155.879 137.666 121.152 1.00 33.43 ? 45  MET C CA  1 
ATOM   3843 C C   . MET C 3 63  ? 155.038 137.764 122.413 1.00 30.73 ? 45  MET C C   1 
ATOM   3844 O O   . MET C 3 63  ? 154.905 136.792 123.161 1.00 28.16 ? 45  MET C O   1 
ATOM   3845 C CB  . MET C 3 63  ? 155.067 137.036 120.016 1.00 38.56 ? 45  MET C CB  1 
ATOM   3846 C CG  . MET C 3 63  ? 155.937 136.481 118.889 1.00 40.11 ? 45  MET C CG  1 
ATOM   3847 S SD  . MET C 3 63  ? 155.100 136.218 117.313 1.00 36.47 ? 45  MET C SD  1 
ATOM   3848 C CE  . MET C 3 63  ? 153.823 135.037 117.735 1.00 31.58 ? 45  MET C CE  1 
ATOM   3849 N N   . ARG C 3 64  ? 154.470 138.947 122.635 1.00 31.64 ? 46  ARG C N   1 
ATOM   3850 C CA  . ARG C 3 64  ? 153.704 139.254 123.833 1.00 33.56 ? 46  ARG C CA  1 
ATOM   3851 C C   . ARG C 3 64  ? 152.325 139.751 123.432 1.00 29.48 ? 46  ARG C C   1 
ATOM   3852 O O   . ARG C 3 64  ? 152.150 140.390 122.393 1.00 34.44 ? 46  ARG C O   1 
ATOM   3853 C CB  . ARG C 3 64  ? 154.413 140.307 124.694 1.00 32.36 ? 46  ARG C CB  1 
ATOM   3854 N N   . THR C 3 65  ? 151.345 139.454 124.279 1.00 26.26 ? 47  THR C N   1 
ATOM   3855 C CA  . THR C 3 65  ? 149.952 139.791 123.976 1.00 28.76 ? 47  THR C CA  1 
ATOM   3856 C C   . THR C 3 65  ? 149.809 141.309 124.010 1.00 31.09 ? 47  THR C C   1 
ATOM   3857 O O   . THR C 3 65  ? 149.578 141.908 125.061 1.00 39.50 ? 47  THR C O   1 
ATOM   3858 C CB  . THR C 3 65  ? 148.967 139.109 124.929 1.00 32.12 ? 47  THR C CB  1 
ATOM   3859 O OG1 . THR C 3 65  ? 147.680 139.723 124.796 1.00 31.77 ? 47  THR C OG1 1 
ATOM   3860 C CG2 . THR C 3 65  ? 149.387 139.167 126.410 1.00 35.68 ? 47  THR C CG2 1 
ATOM   3861 N N   . ARG C 3 66  ? 149.948 141.934 122.838 1.00 30.04 ? 48  ARG C N   1 
ATOM   3862 C CA  . ARG C 3 66  ? 149.841 143.385 122.748 1.00 23.12 ? 48  ARG C CA  1 
ATOM   3863 C C   . ARG C 3 66  ? 148.437 143.859 123.091 1.00 27.47 ? 48  ARG C C   1 
ATOM   3864 O O   . ARG C 3 66  ? 148.265 144.938 123.669 1.00 35.95 ? 48  ARG C O   1 
ATOM   3865 C CB  . ARG C 3 66  ? 150.230 143.854 121.347 1.00 22.76 ? 48  ARG C CB  1 
ATOM   3866 C CG  . ARG C 3 66  ? 151.703 143.693 121.013 1.00 33.81 ? 48  ARG C CG  1 
ATOM   3867 C CD  . ARG C 3 66  ? 152.583 144.672 121.773 1.00 37.45 ? 48  ARG C CD  1 
ATOM   3868 N NE  . ARG C 3 66  ? 153.866 144.868 121.104 1.00 33.85 ? 48  ARG C NE  1 
ATOM   3869 C CZ  . ARG C 3 66  ? 154.965 144.153 121.311 1.00 37.99 ? 48  ARG C CZ  1 
ATOM   3870 N NH1 . ARG C 3 66  ? 154.990 143.128 122.151 1.00 38.89 ? 48  ARG C NH1 1 
ATOM   3871 N NH2 . ARG C 3 66  ? 156.073 144.467 120.647 1.00 36.41 ? 48  ARG C NH2 1 
ATOM   3872 N N   . ARG C 3 67  ? 147.419 143.081 122.723 1.00 27.21 ? 49  ARG C N   1 
ATOM   3873 C CA  . ARG C 3 67  ? 146.035 143.400 123.037 1.00 28.91 ? 49  ARG C CA  1 
ATOM   3874 C C   . ARG C 3 67  ? 145.256 142.134 123.349 1.00 21.02 ? 49  ARG C C   1 
ATOM   3875 O O   . ARG C 3 67  ? 145.425 141.111 122.682 1.00 35.94 ? 49  ARG C O   1 
ATOM   3876 C CB  . ARG C 3 67  ? 145.375 144.137 121.875 1.00 32.95 ? 49  ARG C CB  1 
ATOM   3877 C CG  . ARG C 3 67  ? 145.379 145.647 122.039 1.00 40.05 ? 49  ARG C CG  1 
ATOM   3878 C CD  . ARG C 3 67  ? 145.087 146.374 120.735 1.00 36.28 ? 49  ARG C CD  1 
ATOM   3879 N NE  . ARG C 3 67  ? 145.532 147.764 120.736 1.00 33.00 ? 49  ARG C NE  1 
ATOM   3880 C CZ  . ARG C 3 67  ? 146.796 148.170 120.717 1.00 31.99 ? 49  ARG C CZ  1 
ATOM   3881 N NH1 . ARG C 3 67  ? 147.807 147.317 120.760 1.00 29.46 ? 49  ARG C NH1 1 
ATOM   3882 N NH2 . ARG C 3 67  ? 147.053 149.472 120.655 1.00 35.59 ? 49  ARG C NH2 1 
ATOM   3883 N N   . THR C 3 68  ? 144.403 142.219 124.367 1.00 20.39 ? 50  THR C N   1 
ATOM   3884 C CA  . THR C 3 68  ? 143.461 141.169 124.728 1.00 23.07 ? 50  THR C CA  1 
ATOM   3885 C C   . THR C 3 68  ? 142.058 141.718 124.525 1.00 32.04 ? 50  THR C C   1 
ATOM   3886 O O   . THR C 3 68  ? 141.695 142.731 125.130 1.00 34.54 ? 50  THR C O   1 
ATOM   3887 C CB  . THR C 3 68  ? 143.659 140.723 126.181 1.00 30.33 ? 50  THR C CB  1 
ATOM   3888 O OG1 . THR C 3 68  ? 144.889 140.001 126.297 1.00 31.69 ? 50  THR C OG1 1 
ATOM   3889 C CG2 . THR C 3 68  ? 142.521 139.827 126.644 1.00 32.50 ? 50  THR C CG2 1 
ATOM   3890 N N   . LEU C 3 69  ? 141.274 141.044 123.689 1.00 31.37 ? 51  LEU C N   1 
ATOM   3891 C CA  . LEU C 3 69  ? 139.942 141.497 123.314 1.00 28.50 ? 51  LEU C CA  1 
ATOM   3892 C C   . LEU C 3 69  ? 138.927 140.681 124.096 1.00 31.29 ? 51  LEU C C   1 
ATOM   3893 O O   . LEU C 3 69  ? 138.904 139.451 123.994 1.00 31.87 ? 51  LEU C O   1 
ATOM   3894 C CB  . LEU C 3 69  ? 139.717 141.356 121.806 1.00 27.56 ? 51  LEU C CB  1 
ATOM   3895 C CG  . LEU C 3 69  ? 140.864 141.843 120.911 1.00 25.76 ? 51  LEU C CG  1 
ATOM   3896 C CD1 . LEU C 3 69  ? 140.503 141.693 119.446 1.00 18.86 ? 51  LEU C CD1 1 
ATOM   3897 C CD2 . LEU C 3 69  ? 141.250 143.275 121.223 1.00 37.60 ? 51  LEU C CD2 1 
ATOM   3898 N N   . ARG C 3 70  ? 138.098 141.374 124.872 1.00 37.97 ? 52  ARG C N   1 
ATOM   3899 C CA  . ARG C 3 70  ? 137.202 140.754 125.835 1.00 33.72 ? 52  ARG C CA  1 
ATOM   3900 C C   . ARG C 3 70  ? 135.802 141.314 125.644 1.00 32.55 ? 52  ARG C C   1 
ATOM   3901 O O   . ARG C 3 70  ? 135.614 142.431 125.156 1.00 35.08 ? 52  ARG C O   1 
ATOM   3902 C CB  . ARG C 3 70  ? 137.685 140.985 127.276 1.00 31.32 ? 52  ARG C CB  1 
ATOM   3903 C CG  . ARG C 3 70  ? 137.878 142.451 127.670 1.00 38.80 ? 52  ARG C CG  1 
ATOM   3904 C CD  . ARG C 3 70  ? 139.198 142.688 128.397 1.00 37.02 ? 52  ARG C CD  1 
ATOM   3905 N NE  . ARG C 3 70  ? 139.368 141.812 129.551 1.00 37.41 ? 52  ARG C NE  1 
ATOM   3906 C CZ  . ARG C 3 70  ? 140.524 141.538 130.145 1.00 35.31 ? 52  ARG C CZ  1 
ATOM   3907 N NH1 . ARG C 3 70  ? 141.668 142.066 129.732 1.00 32.81 ? 52  ARG C NH1 1 
ATOM   3908 N NH2 . ARG C 3 70  ? 140.535 140.714 131.188 1.00 37.51 ? 52  ARG C NH2 1 
ATOM   3909 N N   . GLY C 3 71  ? 134.820 140.517 126.057 1.00 30.70 ? 53  GLY C N   1 
ATOM   3910 C CA  . GLY C 3 71  ? 133.419 140.764 125.782 1.00 32.71 ? 53  GLY C CA  1 
ATOM   3911 C C   . GLY C 3 71  ? 132.660 139.549 125.296 1.00 34.13 ? 53  GLY C C   1 
ATOM   3912 O O   . GLY C 3 71  ? 131.430 139.615 125.192 1.00 32.16 ? 53  GLY C O   1 
ATOM   3913 N N   . HIS C 3 72  ? 133.344 138.443 125.009 1.00 34.16 ? 54  HIS C N   1 
ATOM   3914 C CA  . HIS C 3 72  ? 132.705 137.160 124.748 1.00 36.39 ? 54  HIS C CA  1 
ATOM   3915 C C   . HIS C 3 72  ? 132.536 136.460 126.088 1.00 39.93 ? 54  HIS C C   1 
ATOM   3916 O O   . HIS C 3 72  ? 133.518 136.247 126.806 1.00 33.17 ? 54  HIS C O   1 
ATOM   3917 C CB  . HIS C 3 72  ? 133.541 136.299 123.797 1.00 35.52 ? 54  HIS C CB  1 
ATOM   3918 C CG  . HIS C 3 72  ? 133.154 136.421 122.354 1.00 33.54 ? 54  HIS C CG  1 
ATOM   3919 N ND1 . HIS C 3 72  ? 131.852 136.312 121.914 1.00 38.71 ? 54  HIS C ND1 1 
ATOM   3920 C CD2 . HIS C 3 72  ? 133.906 136.627 121.248 1.00 22.45 ? 54  HIS C CD2 1 
ATOM   3921 C CE1 . HIS C 3 72  ? 131.818 136.461 120.602 1.00 28.53 ? 54  HIS C CE1 1 
ATOM   3922 N NE2 . HIS C 3 72  ? 133.052 136.650 120.173 1.00 17.19 ? 54  HIS C NE2 1 
ATOM   3923 N N   . LEU C 3 73  ? 131.296 136.128 126.431 1.00 47.13 ? 55  LEU C N   1 
ATOM   3924 C CA  . LEU C 3 73  ? 130.966 135.529 127.718 1.00 42.32 ? 55  LEU C CA  1 
ATOM   3925 C C   . LEU C 3 73  ? 130.963 134.005 127.694 1.00 40.32 ? 55  LEU C C   1 
ATOM   3926 O O   . LEU C 3 73  ? 130.590 133.391 128.699 1.00 42.30 ? 55  LEU C O   1 
ATOM   3927 C CB  . LEU C 3 73  ? 129.603 136.045 128.194 1.00 41.94 ? 55  LEU C CB  1 
ATOM   3928 C CG  . LEU C 3 73  ? 129.497 137.567 128.366 1.00 44.67 ? 55  LEU C CG  1 
ATOM   3929 C CD1 . LEU C 3 73  ? 128.077 137.994 128.654 1.00 40.47 ? 55  LEU C CD1 1 
ATOM   3930 C CD2 . LEU C 3 73  ? 130.409 138.054 129.481 1.00 43.06 ? 55  LEU C CD2 1 
ATOM   3931 N N   . ALA C 3 74  ? 131.360 133.382 126.584 1.00 43.60 ? 56  ALA C N   1 
ATOM   3932 C CA  . ALA C 3 74  ? 131.437 131.934 126.483 1.00 41.83 ? 56  ALA C CA  1 
ATOM   3933 C C   . ALA C 3 74  ? 132.620 131.564 125.598 1.00 40.14 ? 56  ALA C C   1 
ATOM   3934 O O   . ALA C 3 74  ? 133.370 132.426 125.137 1.00 41.96 ? 56  ALA C O   1 
ATOM   3935 C CB  . ALA C 3 74  ? 130.139 131.343 125.929 1.00 37.16 ? 56  ALA C CB  1 
ATOM   3936 N N   . LYS C 3 75  ? 132.767 130.266 125.351 1.00 40.92 ? 57  LYS C N   1 
ATOM   3937 C CA  . LYS C 3 75  ? 133.960 129.761 124.677 1.00 39.12 ? 57  LYS C CA  1 
ATOM   3938 C C   . LYS C 3 75  ? 133.981 130.189 123.211 1.00 42.25 ? 57  LYS C C   1 
ATOM   3939 O O   . LYS C 3 75  ? 132.962 130.135 122.517 1.00 45.40 ? 57  LYS C O   1 
ATOM   3940 C CB  . LYS C 3 75  ? 134.046 128.229 124.790 1.00 42.73 ? 57  LYS C CB  1 
ATOM   3941 C CG  . LYS C 3 75  ? 133.483 127.586 126.065 1.00 50.63 ? 57  LYS C CG  1 
ATOM   3942 C CD  . LYS C 3 75  ? 133.887 126.123 126.186 1.00 47.46 ? 57  LYS C CD  1 
ATOM   3943 C CE  . LYS C 3 75  ? 133.089 125.404 127.266 1.00 42.53 ? 57  LYS C CE  1 
ATOM   3944 N NZ  . LYS C 3 75  ? 133.369 125.936 128.628 1.00 41.55 ? 57  LYS C NZ  1 
ATOM   3945 N N   . ILE C 3 76  ? 135.141 130.708 122.801 1.00 41.59 ? 58  ILE C N   1 
ATOM   3946 C CA  . ILE C 3 76  ? 135.312 131.154 121.390 1.00 36.11 ? 58  ILE C CA  1 
ATOM   3947 C C   . ILE C 3 76  ? 135.721 129.922 120.578 1.00 33.67 ? 58  ILE C C   1 
ATOM   3948 O O   . ILE C 3 76  ? 136.575 129.155 121.065 1.00 41.42 ? 58  ILE C O   1 
ATOM   3949 C CB  . ILE C 3 76  ? 136.362 132.276 121.304 1.00 32.21 ? 58  ILE C CB  1 
ATOM   3950 C CG1 . ILE C 3 76  ? 136.055 133.401 122.292 1.00 32.87 ? 58  ILE C CG1 1 
ATOM   3951 C CG2 . ILE C 3 76  ? 136.499 132.797 119.874 1.00 31.86 ? 58  ILE C CG2 1 
ATOM   3952 C CD1 . ILE C 3 76  ? 137.122 134.477 122.355 1.00 36.41 ? 58  ILE C CD1 1 
ATOM   3953 N N   . TYR C 3 77  ? 135.107 129.729 119.414 1.00 31.13 ? 59  TYR C N   1 
ATOM   3954 C CA  . TYR C 3 77  ? 135.412 128.583 118.557 1.00 37.90 ? 59  TYR C CA  1 
ATOM   3955 C C   . TYR C 3 77  ? 136.187 128.979 117.304 1.00 40.99 ? 59  TYR C C   1 
ATOM   3956 O O   . TYR C 3 77  ? 137.092 128.248 116.886 1.00 43.32 ? 59  TYR C O   1 
ATOM   3957 C CB  . TYR C 3 77  ? 134.128 127.840 118.189 1.00 35.14 ? 59  TYR C CB  1 
ATOM   3958 C CG  . TYR C 3 77  ? 133.611 126.969 119.314 1.00 42.46 ? 59  TYR C CG  1 
ATOM   3959 C CD1 . TYR C 3 77  ? 133.256 127.504 120.538 1.00 43.96 ? 59  TYR C CD1 1 
ATOM   3960 C CD2 . TYR C 3 77  ? 133.519 125.594 119.159 1.00 49.29 ? 59  TYR C CD2 1 
ATOM   3961 C CE1 . TYR C 3 77  ? 132.821 126.707 121.562 1.00 47.03 ? 59  TYR C CE1 1 
ATOM   3962 C CE2 . TYR C 3 77  ? 133.069 124.788 120.184 1.00 46.56 ? 59  TYR C CE2 1 
ATOM   3963 C CZ  . TYR C 3 77  ? 132.718 125.356 121.385 1.00 48.51 ? 59  TYR C CZ  1 
ATOM   3964 O OH  . TYR C 3 77  ? 132.266 124.586 122.431 1.00 46.60 ? 59  TYR C OH  1 
ATOM   3965 N N   . ALA C 3 78  ? 135.852 130.113 116.688 1.00 28.49 ? 60  ALA C N   1 
ATOM   3966 C CA  . ALA C 3 78  ? 136.432 130.478 115.402 1.00 24.00 ? 60  ALA C CA  1 
ATOM   3967 C C   . ALA C 3 78  ? 136.634 131.982 115.320 1.00 30.23 ? 60  ALA C C   1 
ATOM   3968 O O   . ALA C 3 78  ? 135.898 132.760 115.929 1.00 36.24 ? 60  ALA C O   1 
ATOM   3969 C CB  . ALA C 3 78  ? 135.547 130.007 114.244 1.00 23.41 ? 60  ALA C CB  1 
ATOM   3970 N N   . MET C 3 79  ? 137.660 132.372 114.564 1.00 27.87 ? 61  MET C N   1 
ATOM   3971 C CA  . MET C 3 79  ? 137.935 133.758 114.222 1.00 15.89 ? 61  MET C CA  1 
ATOM   3972 C C   . MET C 3 79  ? 138.483 133.817 112.806 1.00 20.20 ? 61  MET C C   1 
ATOM   3973 O O   . MET C 3 79  ? 139.023 132.828 112.305 1.00 29.59 ? 61  MET C O   1 
ATOM   3974 C CB  . MET C 3 79  ? 138.941 134.415 115.181 1.00 14.37 ? 61  MET C CB  1 
ATOM   3975 C CG  . MET C 3 79  ? 140.344 133.794 115.158 1.00 22.96 ? 61  MET C CG  1 
ATOM   3976 S SD  . MET C 3 79  ? 141.563 134.445 113.988 1.00 37.34 ? 61  MET C SD  1 
ATOM   3977 C CE  . MET C 3 79  ? 141.623 136.179 114.383 1.00 14.96 ? 61  MET C CE  1 
ATOM   3978 N N   . HIS C 3 80  ? 138.340 134.976 112.164 1.00 15.23 ? 62  HIS C N   1 
ATOM   3979 C CA  . HIS C 3 80  ? 138.957 135.228 110.870 1.00 17.75 ? 62  HIS C CA  1 
ATOM   3980 C C   . HIS C 3 80  ? 139.356 136.692 110.765 1.00 17.77 ? 62  HIS C C   1 
ATOM   3981 O O   . HIS C 3 80  ? 138.605 137.576 111.185 1.00 28.14 ? 62  HIS C O   1 
ATOM   3982 C CB  . HIS C 3 80  ? 138.017 134.860 109.722 1.00 15.95 ? 62  HIS C CB  1 
ATOM   3983 C CG  . HIS C 3 80  ? 138.726 134.524 108.447 1.00 10.33 ? 62  HIS C CG  1 
ATOM   3984 N ND1 . HIS C 3 80  ? 138.438 135.141 107.252 1.00 11.78 ? 62  HIS C ND1 1 
ATOM   3985 C CD2 . HIS C 3 80  ? 139.696 133.620 108.178 1.00 17.42 ? 62  HIS C CD2 1 
ATOM   3986 C CE1 . HIS C 3 80  ? 139.209 134.643 106.304 1.00 16.63 ? 62  HIS C CE1 1 
ATOM   3987 N NE2 . HIS C 3 80  ? 139.982 133.718 106.840 1.00 18.15 ? 62  HIS C NE2 1 
ATOM   3988 N N   . TRP C 3 81  ? 140.534 136.938 110.201 1.00 17.74 ? 63  TRP C N   1 
ATOM   3989 C CA  . TRP C 3 81  ? 140.997 138.297 109.961 1.00 17.79 ? 63  TRP C CA  1 
ATOM   3990 C C   . TRP C 3 81  ? 140.328 138.890 108.729 1.00 25.35 ? 63  TRP C C   1 
ATOM   3991 O O   . TRP C 3 81  ? 139.996 138.178 107.779 1.00 38.37 ? 63  TRP C O   1 
ATOM   3992 C CB  . TRP C 3 81  ? 142.510 138.311 109.759 1.00 20.75 ? 63  TRP C CB  1 
ATOM   3993 C CG  . TRP C 3 81  ? 143.310 138.322 111.012 1.00 18.32 ? 63  TRP C CG  1 
ATOM   3994 C CD1 . TRP C 3 81  ? 144.008 137.282 111.544 1.00 20.63 ? 63  TRP C CD1 1 
ATOM   3995 C CD2 . TRP C 3 81  ? 143.525 139.435 111.880 1.00 16.15 ? 63  TRP C CD2 1 
ATOM   3996 N NE1 . TRP C 3 81  ? 144.636 137.674 112.696 1.00 8.80  ? 63  TRP C NE1 1 
ATOM   3997 C CE2 . TRP C 3 81  ? 144.355 138.994 112.925 1.00 15.18 ? 63  TRP C CE2 1 
ATOM   3998 C CE3 . TRP C 3 81  ? 143.092 140.763 111.878 1.00 21.63 ? 63  TRP C CE3 1 
ATOM   3999 C CZ2 . TRP C 3 81  ? 144.762 139.831 113.955 1.00 20.51 ? 63  TRP C CZ2 1 
ATOM   4000 C CZ3 . TRP C 3 81  ? 143.495 141.590 112.902 1.00 16.90 ? 63  TRP C CZ3 1 
ATOM   4001 C CH2 . TRP C 3 81  ? 144.321 141.122 113.927 1.00 14.93 ? 63  TRP C CH2 1 
ATOM   4002 N N   . GLY C 3 82  ? 140.141 140.208 108.745 1.00 28.25 ? 64  GLY C N   1 
ATOM   4003 C CA  . GLY C 3 82  ? 139.780 140.916 107.536 1.00 18.70 ? 64  GLY C CA  1 
ATOM   4004 C C   . GLY C 3 82  ? 140.989 141.193 106.663 1.00 28.91 ? 64  GLY C C   1 
ATOM   4005 O O   . GLY C 3 82  ? 142.133 141.208 107.117 1.00 35.09 ? 64  GLY C O   1 
ATOM   4006 N N   . THR C 3 83  ? 140.729 141.414 105.373 1.00 32.39 ? 65  THR C N   1 
ATOM   4007 C CA  . THR C 3 83  ? 141.817 141.721 104.448 1.00 31.07 ? 65  THR C CA  1 
ATOM   4008 C C   . THR C 3 83  ? 142.436 143.079 104.751 1.00 35.04 ? 65  THR C C   1 
ATOM   4009 O O   . THR C 3 83  ? 143.625 143.301 104.493 1.00 31.64 ? 65  THR C O   1 
ATOM   4010 C CB  . THR C 3 83  ? 141.316 141.680 103.007 1.00 27.20 ? 65  THR C CB  1 
ATOM   4011 O OG1 . THR C 3 83  ? 140.126 142.469 102.890 1.00 34.34 ? 65  THR C OG1 1 
ATOM   4012 C CG2 . THR C 3 83  ? 141.030 140.255 102.585 1.00 33.62 ? 65  THR C CG2 1 
ATOM   4013 N N   . ASP C 3 84  ? 141.644 144.005 105.298 1.00 37.11 ? 66  ASP C N   1 
ATOM   4014 C CA  . ASP C 3 84  ? 142.169 145.326 105.639 1.00 30.15 ? 66  ASP C CA  1 
ATOM   4015 C C   . ASP C 3 84  ? 143.208 145.261 106.758 1.00 25.95 ? 66  ASP C C   1 
ATOM   4016 O O   . ASP C 3 84  ? 143.946 146.230 106.970 1.00 32.71 ? 66  ASP C O   1 
ATOM   4017 C CB  . ASP C 3 84  ? 141.028 146.269 106.032 1.00 35.64 ? 66  ASP C CB  1 
ATOM   4018 C CG  . ASP C 3 84  ? 140.205 145.748 107.192 1.00 35.26 ? 66  ASP C CG  1 
ATOM   4019 O OD1 . ASP C 3 84  ? 139.430 144.788 106.993 1.00 27.36 ? 66  ASP C OD1 1 
ATOM   4020 O OD2 . ASP C 3 84  ? 140.331 146.304 108.301 1.00 36.13 ? 66  ASP C OD2 1 
ATOM   4021 N N   . SER C 3 85  ? 143.260 144.152 107.504 1.00 23.35 ? 67  SER C N   1 
ATOM   4022 C CA  . SER C 3 85  ? 144.243 143.818 108.539 1.00 23.57 ? 67  SER C CA  1 
ATOM   4023 C C   . SER C 3 85  ? 143.948 144.488 109.876 1.00 23.26 ? 67  SER C C   1 
ATOM   4024 O O   . SER C 3 85  ? 144.670 144.223 110.839 1.00 19.29 ? 67  SER C O   1 
ATOM   4025 C CB  . SER C 3 85  ? 145.682 144.166 108.120 1.00 36.89 ? 67  SER C CB  1 
ATOM   4026 O OG  . SER C 3 85  ? 145.895 143.863 106.755 1.00 32.20 ? 67  SER C OG  1 
ATOM   4027 N N   . ARG C 3 86  ? 142.925 145.339 109.970 1.00 30.99 ? 68  ARG C N   1 
ATOM   4028 C CA  . ARG C 3 86  ? 142.519 145.982 111.213 1.00 27.16 ? 68  ARG C CA  1 
ATOM   4029 C C   . ARG C 3 86  ? 141.282 145.350 111.838 1.00 25.54 ? 68  ARG C C   1 
ATOM   4030 O O   . ARG C 3 86  ? 141.056 145.532 113.038 1.00 25.63 ? 68  ARG C O   1 
ATOM   4031 C CB  . ARG C 3 86  ? 142.252 147.465 110.951 1.00 16.99 ? 68  ARG C CB  1 
ATOM   4032 C CG  . ARG C 3 86  ? 141.842 148.264 112.163 1.00 21.22 ? 68  ARG C CG  1 
ATOM   4033 C CD  . ARG C 3 86  ? 142.250 149.708 111.990 1.00 32.23 ? 68  ARG C CD  1 
ATOM   4034 N NE  . ARG C 3 86  ? 141.669 150.581 113.002 1.00 25.81 ? 68  ARG C NE  1 
ATOM   4035 C CZ  . ARG C 3 86  ? 142.032 151.839 113.220 1.00 24.41 ? 68  ARG C CZ  1 
ATOM   4036 N NH1 . ARG C 3 86  ? 142.991 152.423 112.515 1.00 26.37 ? 68  ARG C NH1 1 
ATOM   4037 N NH2 . ARG C 3 86  ? 141.413 152.535 114.168 1.00 26.00 ? 68  ARG C NH2 1 
ATOM   4038 N N   . LEU C 3 87  ? 140.498 144.596 111.066 1.00 21.52 ? 69  LEU C N   1 
ATOM   4039 C CA  . LEU C 3 87  ? 139.191 144.104 111.472 1.00 5.00  ? 69  LEU C CA  1 
ATOM   4040 C C   . LEU C 3 87  ? 139.207 142.586 111.488 1.00 14.13 ? 69  LEU C C   1 
ATOM   4041 O O   . LEU C 3 87  ? 139.746 141.958 110.573 1.00 26.01 ? 69  LEU C O   1 
ATOM   4042 C CB  . LEU C 3 87  ? 138.108 144.602 110.507 1.00 21.22 ? 69  LEU C CB  1 
ATOM   4043 C CG  . LEU C 3 87  ? 137.376 145.888 110.889 1.00 22.67 ? 69  LEU C CG  1 
ATOM   4044 C CD1 . LEU C 3 87  ? 136.723 146.510 109.670 1.00 25.19 ? 69  LEU C CD1 1 
ATOM   4045 C CD2 . LEU C 3 87  ? 136.341 145.617 111.953 1.00 28.61 ? 69  LEU C CD2 1 
ATOM   4046 N N   . LEU C 3 88  ? 138.626 142.002 112.535 1.00 22.02 ? 70  LEU C N   1 
ATOM   4047 C CA  . LEU C 3 88  ? 138.454 140.561 112.646 1.00 18.48 ? 70  LEU C CA  1 
ATOM   4048 C C   . LEU C 3 88  ? 137.051 140.263 113.151 1.00 17.05 ? 70  LEU C C   1 
ATOM   4049 O O   . LEU C 3 88  ? 136.398 141.109 113.764 1.00 31.58 ? 70  LEU C O   1 
ATOM   4050 C CB  . LEU C 3 88  ? 139.516 139.918 113.571 1.00 25.56 ? 70  LEU C CB  1 
ATOM   4051 C CG  . LEU C 3 88  ? 139.380 139.901 115.102 1.00 25.21 ? 70  LEU C CG  1 
ATOM   4052 C CD1 . LEU C 3 88  ? 140.319 138.888 115.694 1.00 19.98 ? 70  LEU C CD1 1 
ATOM   4053 C CD2 . LEU C 3 88  ? 139.679 141.253 115.669 1.00 21.29 ? 70  LEU C CD2 1 
ATOM   4054 N N   . VAL C 3 89  ? 136.602 139.041 112.881 1.00 14.99 ? 71  VAL C N   1 
ATOM   4055 C CA  . VAL C 3 89  ? 135.318 138.521 113.337 1.00 19.02 ? 71  VAL C CA  1 
ATOM   4056 C C   . VAL C 3 89  ? 135.615 137.322 114.225 1.00 26.30 ? 71  VAL C C   1 
ATOM   4057 O O   . VAL C 3 89  ? 136.625 136.642 114.022 1.00 30.51 ? 71  VAL C O   1 
ATOM   4058 C CB  . VAL C 3 89  ? 134.402 138.140 112.153 1.00 17.86 ? 71  VAL C CB  1 
ATOM   4059 C CG1 . VAL C 3 89  ? 135.105 137.209 111.160 1.00 20.61 ? 71  VAL C CG1 1 
ATOM   4060 C CG2 . VAL C 3 89  ? 133.115 137.518 112.639 1.00 17.05 ? 71  VAL C CG2 1 
ATOM   4061 N N   . SER C 3 90  ? 134.773 137.097 115.235 1.00 27.66 ? 72  SER C N   1 
ATOM   4062 C CA  . SER C 3 90  ? 134.899 135.953 116.129 1.00 22.69 ? 72  SER C CA  1 
ATOM   4063 C C   . SER C 3 90  ? 133.527 135.349 116.389 1.00 23.37 ? 72  SER C C   1 
ATOM   4064 O O   . SER C 3 90  ? 132.516 136.056 116.363 1.00 28.67 ? 72  SER C O   1 
ATOM   4065 C CB  . SER C 3 90  ? 135.554 136.351 117.452 1.00 18.10 ? 72  SER C CB  1 
ATOM   4066 O OG  . SER C 3 90  ? 134.693 137.165 118.222 1.00 30.24 ? 72  SER C OG  1 
ATOM   4067 N N   . ALA C 3 91  ? 133.503 134.038 116.632 1.00 22.13 ? 73  ALA C N   1 
ATOM   4068 C CA  . ALA C 3 91  ? 132.292 133.274 116.903 1.00 20.32 ? 73  ALA C CA  1 
ATOM   4069 C C   . ALA C 3 91  ? 132.444 132.558 118.234 1.00 32.81 ? 73  ALA C C   1 
ATOM   4070 O O   . ALA C 3 91  ? 133.545 132.133 118.593 1.00 39.92 ? 73  ALA C O   1 
ATOM   4071 C CB  . ALA C 3 91  ? 132.016 132.251 115.803 1.00 26.33 ? 73  ALA C CB  1 
ATOM   4072 N N   . SER C 3 92  ? 131.336 132.421 118.959 1.00 32.25 ? 74  SER C N   1 
ATOM   4073 C CA  . SER C 3 92  ? 131.350 131.889 120.311 1.00 30.41 ? 74  SER C CA  1 
ATOM   4074 C C   . SER C 3 92  ? 130.073 131.117 120.610 1.00 36.59 ? 74  SER C C   1 
ATOM   4075 O O   . SER C 3 92  ? 129.107 131.134 119.843 1.00 41.51 ? 74  SER C O   1 
ATOM   4076 C CB  . SER C 3 92  ? 131.536 133.004 121.329 1.00 32.13 ? 74  SER C CB  1 
ATOM   4077 O OG  . SER C 3 92  ? 132.181 132.532 122.495 1.00 44.03 ? 74  SER C OG  1 
ATOM   4078 N N   . GLN C 3 93  ? 130.097 130.405 121.740 1.00 44.40 ? 75  GLN C N   1 
ATOM   4079 C CA  . GLN C 3 93  ? 128.946 129.546 122.117 1.00 45.23 ? 75  GLN C CA  1 
ATOM   4080 C C   . GLN C 3 93  ? 127.812 130.403 122.703 1.00 47.87 ? 75  GLN C C   1 
ATOM   4081 O O   . GLN C 3 93  ? 126.653 129.957 122.637 1.00 51.70 ? 75  GLN C O   1 
ATOM   4082 C CB  . GLN C 3 93  ? 129.474 128.507 123.107 1.00 45.88 ? 75  GLN C CB  1 
ATOM   4083 C CG  . GLN C 3 93  ? 128.479 127.420 123.493 1.00 54.51 ? 75  GLN C CG  1 
ATOM   4084 C CD  . GLN C 3 93  ? 129.112 126.315 124.311 1.00 56.43 ? 75  GLN C CD  1 
ATOM   4085 O OE1 . GLN C 3 93  ? 130.323 126.310 124.557 1.00 52.08 ? 75  GLN C OE1 1 
ATOM   4086 N NE2 . GLN C 3 93  ? 128.297 125.362 124.738 1.00 47.24 ? 75  GLN C NE2 1 
ATOM   4087 N N   . ASP C 3 94  ? 128.120 131.584 123.245 1.00 37.21 ? 76  ASP C N   1 
ATOM   4088 C CA  . ASP C 3 94  ? 127.030 132.422 123.743 1.00 34.91 ? 76  ASP C CA  1 
ATOM   4089 C C   . ASP C 3 94  ? 126.053 132.814 122.644 1.00 35.94 ? 76  ASP C C   1 
ATOM   4090 O O   . ASP C 3 94  ? 125.000 133.380 122.951 1.00 43.70 ? 76  ASP C O   1 
ATOM   4091 C CB  . ASP C 3 94  ? 127.554 133.685 124.455 1.00 44.23 ? 76  ASP C CB  1 
ATOM   4092 C CG  . ASP C 3 94  ? 128.593 134.454 123.655 1.00 43.33 ? 76  ASP C CG  1 
ATOM   4093 O OD1 . ASP C 3 94  ? 129.765 134.051 123.710 1.00 43.46 ? 76  ASP C OD1 1 
ATOM   4094 O OD2 . ASP C 3 94  ? 128.239 135.455 123.006 1.00 38.99 ? 76  ASP C OD2 1 
ATOM   4095 N N   . GLY C 3 95  ? 126.373 132.544 121.379 1.00 33.34 ? 77  GLY C N   1 
ATOM   4096 C CA  . GLY C 3 95  ? 125.434 132.723 120.297 1.00 38.73 ? 77  GLY C CA  1 
ATOM   4097 C C   . GLY C 3 95  ? 125.511 134.055 119.599 1.00 38.10 ? 77  GLY C C   1 
ATOM   4098 O O   . GLY C 3 95  ? 124.506 134.487 119.023 1.00 39.19 ? 77  GLY C O   1 
ATOM   4099 N N   . LYS C 3 96  ? 126.659 134.725 119.644 1.00 36.30 ? 78  LYS C N   1 
ATOM   4100 C CA  . LYS C 3 96  ? 126.825 136.053 119.076 1.00 33.21 ? 78  LYS C CA  1 
ATOM   4101 C C   . LYS C 3 96  ? 128.141 136.130 118.321 1.00 27.88 ? 78  LYS C C   1 
ATOM   4102 O O   . LYS C 3 96  ? 129.164 135.618 118.786 1.00 23.90 ? 78  LYS C O   1 
ATOM   4103 C CB  . LYS C 3 96  ? 126.756 137.108 120.178 1.00 30.23 ? 78  LYS C CB  1 
ATOM   4104 C CG  . LYS C 3 96  ? 125.329 137.533 120.470 1.00 39.49 ? 78  LYS C CG  1 
ATOM   4105 C CD  . LYS C 3 96  ? 125.094 137.807 121.944 1.00 35.77 ? 78  LYS C CD  1 
ATOM   4106 C CE  . LYS C 3 96  ? 123.631 138.095 122.271 1.00 40.39 ? 78  LYS C CE  1 
ATOM   4107 N NZ  . LYS C 3 96  ? 122.640 137.136 121.697 1.00 39.70 ? 78  LYS C NZ  1 
ATOM   4108 N N   . LEU C 3 97  ? 128.094 136.759 117.151 1.00 34.41 ? 79  LEU C N   1 
ATOM   4109 C CA  . LEU C 3 97  ? 129.253 137.018 116.312 1.00 25.11 ? 79  LEU C CA  1 
ATOM   4110 C C   . LEU C 3 97  ? 129.609 138.490 116.450 1.00 18.93 ? 79  LEU C C   1 
ATOM   4111 O O   . LEU C 3 97  ? 128.783 139.358 116.152 1.00 34.45 ? 79  LEU C O   1 
ATOM   4112 C CB  . LEU C 3 97  ? 128.941 136.662 114.856 1.00 23.36 ? 79  LEU C CB  1 
ATOM   4113 C CG  . LEU C 3 97  ? 130.104 136.364 113.919 1.00 27.97 ? 79  LEU C CG  1 
ATOM   4114 C CD1 . LEU C 3 97  ? 130.465 134.910 114.004 1.00 29.16 ? 79  LEU C CD1 1 
ATOM   4115 C CD2 . LEU C 3 97  ? 129.743 136.728 112.490 1.00 24.55 ? 79  LEU C CD2 1 
ATOM   4116 N N   . ILE C 3 98  ? 130.830 138.765 116.903 1.00 8.54  ? 80  ILE C N   1 
ATOM   4117 C CA  . ILE C 3 98  ? 131.281 140.113 117.230 1.00 21.44 ? 80  ILE C CA  1 
ATOM   4118 C C   . ILE C 3 98  ? 132.447 140.451 116.316 1.00 24.35 ? 80  ILE C C   1 
ATOM   4119 O O   . ILE C 3 98  ? 133.356 139.635 116.128 1.00 29.69 ? 80  ILE C O   1 
ATOM   4120 C CB  . ILE C 3 98  ? 131.687 140.256 118.719 1.00 20.91 ? 80  ILE C CB  1 
ATOM   4121 C CG1 . ILE C 3 98  ? 130.554 139.794 119.655 1.00 20.25 ? 80  ILE C CG1 1 
ATOM   4122 C CG2 . ILE C 3 98  ? 132.064 141.721 119.037 1.00 26.55 ? 80  ILE C CG2 1 
ATOM   4123 C CD1 . ILE C 3 98  ? 130.940 139.686 121.117 1.00 15.92 ? 80  ILE C CD1 1 
ATOM   4124 N N   . ILE C 3 99  ? 132.415 141.657 115.751 1.00 26.60 ? 81  ILE C N   1 
ATOM   4125 C CA  . ILE C 3 99  ? 133.469 142.179 114.887 1.00 24.13 ? 81  ILE C CA  1 
ATOM   4126 C C   . ILE C 3 99  ? 134.192 143.278 115.650 1.00 22.36 ? 81  ILE C C   1 
ATOM   4127 O O   . ILE C 3 99  ? 133.553 144.204 116.164 1.00 21.03 ? 81  ILE C O   1 
ATOM   4128 C CB  . ILE C 3 99  ? 132.906 142.702 113.552 1.00 21.66 ? 81  ILE C CB  1 
ATOM   4129 C CG1 . ILE C 3 99  ? 132.332 141.554 112.717 1.00 21.90 ? 81  ILE C CG1 1 
ATOM   4130 C CG2 . ILE C 3 99  ? 133.981 143.423 112.755 1.00 19.16 ? 81  ILE C CG2 1 
ATOM   4131 C CD1 . ILE C 3 99  ? 131.198 141.960 111.832 1.00 23.53 ? 81  ILE C CD1 1 
ATOM   4132 N N   . TRP C 3 100 ? 135.519 143.175 115.719 1.00 20.82 ? 82  TRP C N   1 
ATOM   4133 C CA  . TRP C 3 100 ? 136.348 144.061 116.524 1.00 23.96 ? 82  TRP C CA  1 
ATOM   4134 C C   . TRP C 3 100 ? 137.247 144.891 115.626 1.00 15.51 ? 82  TRP C C   1 
ATOM   4135 O O   . TRP C 3 100 ? 137.766 144.406 114.619 1.00 15.78 ? 82  TRP C O   1 
ATOM   4136 C CB  . TRP C 3 100 ? 137.267 143.315 117.512 1.00 28.42 ? 82  TRP C CB  1 
ATOM   4137 C CG  . TRP C 3 100 ? 136.748 142.042 118.111 1.00 28.81 ? 82  TRP C CG  1 
ATOM   4138 C CD1 . TRP C 3 100 ? 136.592 140.835 117.491 1.00 27.16 ? 82  TRP C CD1 1 
ATOM   4139 C CD2 . TRP C 3 100 ? 136.346 141.846 119.468 1.00 29.11 ? 82  TRP C CD2 1 
ATOM   4140 N NE1 . TRP C 3 100 ? 136.106 139.909 118.375 1.00 22.08 ? 82  TRP C NE1 1 
ATOM   4141 C CE2 . TRP C 3 100 ? 135.947 140.504 119.597 1.00 20.67 ? 82  TRP C CE2 1 
ATOM   4142 C CE3 . TRP C 3 100 ? 136.281 142.680 120.587 1.00 26.85 ? 82  TRP C CE3 1 
ATOM   4143 C CZ2 . TRP C 3 100 ? 135.489 139.978 120.798 1.00 25.62 ? 82  TRP C CZ2 1 
ATOM   4144 C CZ3 . TRP C 3 100 ? 135.826 142.156 121.774 1.00 28.20 ? 82  TRP C CZ3 1 
ATOM   4145 C CH2 . TRP C 3 100 ? 135.434 140.818 121.872 1.00 27.91 ? 82  TRP C CH2 1 
ATOM   4146 N N   . ASP C 3 101 ? 137.433 146.147 116.017 1.00 23.46 ? 83  ASP C N   1 
ATOM   4147 C CA  . ASP C 3 101 ? 138.516 146.976 115.508 1.00 19.34 ? 83  ASP C CA  1 
ATOM   4148 C C   . ASP C 3 101 ? 139.729 146.649 116.373 1.00 18.77 ? 83  ASP C C   1 
ATOM   4149 O O   . ASP C 3 101 ? 139.755 146.979 117.562 1.00 33.56 ? 83  ASP C O   1 
ATOM   4150 C CB  . ASP C 3 101 ? 138.131 148.452 115.579 1.00 20.69 ? 83  ASP C CB  1 
ATOM   4151 C CG  . ASP C 3 101 ? 139.284 149.393 115.277 1.00 25.80 ? 83  ASP C CG  1 
ATOM   4152 O OD1 . ASP C 3 101 ? 140.311 148.965 114.712 1.00 24.70 ? 83  ASP C OD1 1 
ATOM   4153 O OD2 . ASP C 3 101 ? 139.157 150.587 115.613 1.00 28.35 ? 83  ASP C OD2 1 
ATOM   4154 N N   . SER C 3 102 ? 140.720 145.976 115.784 1.00 15.36 ? 84  SER C N   1 
ATOM   4155 C CA  . SER C 3 102 ? 141.825 145.444 116.576 1.00 17.01 ? 84  SER C CA  1 
ATOM   4156 C C   . SER C 3 102 ? 142.655 146.550 117.206 1.00 34.75 ? 84  SER C C   1 
ATOM   4157 O O   . SER C 3 102 ? 143.101 146.420 118.350 1.00 45.94 ? 84  SER C O   1 
ATOM   4158 C CB  . SER C 3 102 ? 142.722 144.557 115.717 1.00 23.61 ? 84  SER C CB  1 
ATOM   4159 O OG  . SER C 3 102 ? 142.311 143.213 115.793 1.00 34.88 ? 84  SER C OG  1 
ATOM   4160 N N   . TYR C 3 103 ? 142.901 147.632 116.468 1.00 29.04 ? 85  TYR C N   1 
ATOM   4161 C CA  . TYR C 3 103 ? 143.826 148.651 116.953 1.00 15.85 ? 85  TYR C CA  1 
ATOM   4162 C C   . TYR C 3 103 ? 143.274 149.355 118.188 1.00 20.90 ? 85  TYR C C   1 
ATOM   4163 O O   . TYR C 3 103 ? 144.008 149.588 119.155 1.00 31.10 ? 85  TYR C O   1 
ATOM   4164 C CB  . TYR C 3 103 ? 144.134 149.668 115.848 1.00 22.67 ? 85  TYR C CB  1 
ATOM   4165 C CG  . TYR C 3 103 ? 144.961 149.180 114.655 1.00 14.50 ? 85  TYR C CG  1 
ATOM   4166 C CD1 . TYR C 3 103 ? 145.242 147.834 114.445 1.00 17.91 ? 85  TYR C CD1 1 
ATOM   4167 C CD2 . TYR C 3 103 ? 145.465 150.088 113.737 1.00 27.99 ? 85  TYR C CD2 1 
ATOM   4168 C CE1 . TYR C 3 103 ? 145.983 147.416 113.361 1.00 26.66 ? 85  TYR C CE1 1 
ATOM   4169 C CE2 . TYR C 3 103 ? 146.205 149.674 112.648 1.00 31.42 ? 85  TYR C CE2 1 
ATOM   4170 C CZ  . TYR C 3 103 ? 146.463 148.340 112.468 1.00 31.60 ? 85  TYR C CZ  1 
ATOM   4171 O OH  . TYR C 3 103 ? 147.205 147.928 111.386 1.00 36.17 ? 85  TYR C OH  1 
ATOM   4172 N N   . THR C 3 104 ? 141.979 149.677 118.181 1.00 17.74 ? 86  THR C N   1 
ATOM   4173 C CA  . THR C 3 104 ? 141.327 150.398 119.269 1.00 20.06 ? 86  THR C CA  1 
ATOM   4174 C C   . THR C 3 104 ? 140.488 149.512 120.186 1.00 20.79 ? 86  THR C C   1 
ATOM   4175 O O   . THR C 3 104 ? 139.802 150.046 121.062 1.00 30.35 ? 86  THR C O   1 
ATOM   4176 C CB  . THR C 3 104 ? 140.455 151.524 118.704 1.00 24.61 ? 86  THR C CB  1 
ATOM   4177 O OG1 . THR C 3 104 ? 139.216 150.990 118.225 1.00 31.00 ? 86  THR C OG1 1 
ATOM   4178 C CG2 . THR C 3 104 ? 141.183 152.255 117.584 1.00 20.95 ? 86  THR C CG2 1 
ATOM   4179 N N   . THR C 3 105 ? 140.553 148.183 120.034 1.00 17.82 ? 87  THR C N   1 
ATOM   4180 C CA  . THR C 3 105 ? 139.842 147.210 120.884 1.00 22.33 ? 87  THR C CA  1 
ATOM   4181 C C   . THR C 3 105 ? 138.344 147.505 120.983 1.00 26.79 ? 87  THR C C   1 
ATOM   4182 O O   . THR C 3 105 ? 137.719 147.262 122.017 1.00 36.68 ? 87  THR C O   1 
ATOM   4183 C CB  . THR C 3 105 ? 140.454 147.130 122.294 1.00 32.29 ? 87  THR C CB  1 
ATOM   4184 O OG1 . THR C 3 105 ? 140.564 148.433 122.879 1.00 29.66 ? 87  THR C OG1 1 
ATOM   4185 C CG2 . THR C 3 105 ? 141.844 146.520 122.261 1.00 28.81 ? 87  THR C CG2 1 
ATOM   4186 N N   . ASN C 3 106 ? 137.755 147.997 119.895 1.00 16.11 ? 88  ASN C N   1 
ATOM   4187 C CA  . ASN C 3 106 ? 136.364 148.438 119.873 1.00 17.44 ? 88  ASN C CA  1 
ATOM   4188 C C   . ASN C 3 106 ? 135.530 147.480 119.038 1.00 14.03 ? 88  ASN C C   1 
ATOM   4189 O O   . ASN C 3 106 ? 135.973 147.026 117.980 1.00 27.16 ? 88  ASN C O   1 
ATOM   4190 C CB  . ASN C 3 106 ? 136.248 149.856 119.307 1.00 16.24 ? 88  ASN C CB  1 
ATOM   4191 C CG  . ASN C 3 106 ? 136.572 150.933 120.327 1.00 12.53 ? 88  ASN C CG  1 
ATOM   4192 O OD1 . ASN C 3 106 ? 136.406 150.745 121.531 1.00 13.92 ? 88  ASN C OD1 1 
ATOM   4193 N ND2 . ASN C 3 106 ? 137.033 152.079 119.842 1.00 26.07 ? 88  ASN C ND2 1 
ATOM   4194 N N   . LYS C 3 107 ? 134.320 147.187 119.512 1.00 13.76 ? 89  LYS C N   1 
ATOM   4195 C CA  . LYS C 3 107 ? 133.407 146.284 118.818 1.00 21.28 ? 89  LYS C CA  1 
ATOM   4196 C C   . LYS C 3 107 ? 132.641 147.061 117.755 1.00 34.35 ? 89  LYS C C   1 
ATOM   4197 O O   . LYS C 3 107 ? 131.825 147.931 118.076 1.00 33.09 ? 89  LYS C O   1 
ATOM   4198 C CB  . LYS C 3 107 ? 132.446 145.623 119.801 1.00 22.61 ? 89  LYS C CB  1 
ATOM   4199 C CG  . LYS C 3 107 ? 133.103 145.002 121.015 1.00 25.71 ? 89  LYS C CG  1 
ATOM   4200 C CD  . LYS C 3 107 ? 132.069 144.350 121.909 1.00 28.37 ? 89  LYS C CD  1 
ATOM   4201 C CE  . LYS C 3 107 ? 132.714 143.496 122.980 1.00 31.40 ? 89  LYS C CE  1 
ATOM   4202 N NZ  . LYS C 3 107 ? 133.744 144.237 123.756 1.00 30.94 ? 89  LYS C NZ  1 
ATOM   4203 N N   . VAL C 3 108 ? 132.908 146.751 116.486 1.00 25.36 ? 90  VAL C N   1 
ATOM   4204 C CA  . VAL C 3 108 ? 132.203 147.413 115.395 1.00 15.20 ? 90  VAL C CA  1 
ATOM   4205 C C   . VAL C 3 108 ? 130.758 146.931 115.334 1.00 14.70 ? 90  VAL C C   1 
ATOM   4206 O O   . VAL C 3 108 ? 129.830 147.732 115.176 1.00 23.40 ? 90  VAL C O   1 
ATOM   4207 C CB  . VAL C 3 108 ? 132.961 147.176 114.074 1.00 8.23  ? 90  VAL C CB  1 
ATOM   4208 C CG1 . VAL C 3 108 ? 132.328 147.910 112.895 1.00 15.48 ? 90  VAL C CG1 1 
ATOM   4209 C CG2 . VAL C 3 108 ? 134.407 147.610 114.225 1.00 14.69 ? 90  VAL C CG2 1 
ATOM   4210 N N   . HIS C 3 109 ? 130.547 145.623 115.461 1.00 13.72 ? 91  HIS C N   1 
ATOM   4211 C CA  . HIS C 3 109 ? 129.222 145.022 115.409 1.00 15.46 ? 91  HIS C CA  1 
ATOM   4212 C C   . HIS C 3 109 ? 129.170 143.850 116.374 1.00 16.87 ? 91  HIS C C   1 
ATOM   4213 O O   . HIS C 3 109 ? 130.192 143.232 116.677 1.00 26.78 ? 91  HIS C O   1 
ATOM   4214 C CB  . HIS C 3 109 ? 128.862 144.525 114.001 1.00 22.82 ? 91  HIS C CB  1 
ATOM   4215 C CG  . HIS C 3 109 ? 128.722 145.609 112.977 1.00 16.77 ? 91  HIS C CG  1 
ATOM   4216 N ND1 . HIS C 3 109 ? 129.605 145.764 111.931 1.00 9.73  ? 91  HIS C ND1 1 
ATOM   4217 C CD2 . HIS C 3 109 ? 127.783 146.571 112.822 1.00 18.48 ? 91  HIS C CD2 1 
ATOM   4218 C CE1 . HIS C 3 109 ? 129.223 146.784 111.184 1.00 21.58 ? 91  HIS C CE1 1 
ATOM   4219 N NE2 . HIS C 3 109 ? 128.121 147.292 111.704 1.00 24.37 ? 91  HIS C NE2 1 
ATOM   4220 N N   . ALA C 3 110 ? 127.967 143.562 116.862 1.00 18.46 ? 92  ALA C N   1 
ATOM   4221 C CA  . ALA C 3 110 ? 127.658 142.328 117.571 1.00 17.18 ? 92  ALA C CA  1 
ATOM   4222 C C   . ALA C 3 110 ? 126.367 141.772 116.992 1.00 24.94 ? 92  ALA C C   1 
ATOM   4223 O O   . ALA C 3 110 ? 125.328 142.438 117.041 1.00 31.78 ? 92  ALA C O   1 
ATOM   4224 C CB  . ALA C 3 110 ? 127.519 142.564 119.075 1.00 20.60 ? 92  ALA C CB  1 
ATOM   4225 N N   . ILE C 3 111 ? 126.433 140.560 116.461 1.00 23.11 ? 93  ILE C N   1 
ATOM   4226 C CA  . ILE C 3 111 ? 125.395 140.002 115.597 1.00 26.62 ? 93  ILE C CA  1 
ATOM   4227 C C   . ILE C 3 111 ? 124.697 138.873 116.359 1.00 28.54 ? 93  ILE C C   1 
ATOM   4228 O O   . ILE C 3 111 ? 125.354 137.884 116.693 1.00 26.06 ? 93  ILE C O   1 
ATOM   4229 C CB  . ILE C 3 111 ? 125.976 139.470 114.272 1.00 24.67 ? 93  ILE C CB  1 
ATOM   4230 C CG1 . ILE C 3 111 ? 126.704 140.569 113.480 1.00 26.53 ? 93  ILE C CG1 1 
ATOM   4231 C CG2 . ILE C 3 111 ? 124.876 138.862 113.415 1.00 22.01 ? 93  ILE C CG2 1 
ATOM   4232 C CD1 . ILE C 3 111 ? 127.810 140.042 112.605 1.00 24.60 ? 93  ILE C CD1 1 
ATOM   4233 N N   . PRO C 3 112 ? 123.393 138.968 116.645 1.00 36.71 ? 94  PRO C N   1 
ATOM   4234 C CA  . PRO C 3 112 ? 122.717 137.818 117.261 1.00 30.49 ? 94  PRO C CA  1 
ATOM   4235 C C   . PRO C 3 112 ? 122.529 136.683 116.267 1.00 32.55 ? 94  PRO C C   1 
ATOM   4236 O O   . PRO C 3 112 ? 122.218 136.906 115.095 1.00 34.73 ? 94  PRO C O   1 
ATOM   4237 C CB  . PRO C 3 112 ? 121.373 138.400 117.707 1.00 32.82 ? 94  PRO C CB  1 
ATOM   4238 C CG  . PRO C 3 112 ? 121.114 139.457 116.727 1.00 34.38 ? 94  PRO C CG  1 
ATOM   4239 C CD  . PRO C 3 112 ? 122.451 140.097 116.509 1.00 37.29 ? 94  PRO C CD  1 
ATOM   4240 N N   . LEU C 3 113 ? 122.700 135.455 116.758 1.00 39.37 ? 95  LEU C N   1 
ATOM   4241 C CA  . LEU C 3 113 ? 122.669 134.246 115.943 1.00 40.41 ? 95  LEU C CA  1 
ATOM   4242 C C   . LEU C 3 113 ? 121.509 133.369 116.386 1.00 41.43 ? 95  LEU C C   1 
ATOM   4243 O O   . LEU C 3 113 ? 121.236 133.251 117.585 1.00 36.90 ? 95  LEU C O   1 
ATOM   4244 C CB  . LEU C 3 113 ? 123.984 133.473 116.060 1.00 33.66 ? 95  LEU C CB  1 
ATOM   4245 C CG  . LEU C 3 113 ? 125.264 134.254 115.769 1.00 31.50 ? 95  LEU C CG  1 
ATOM   4246 C CD1 . LEU C 3 113 ? 126.460 133.371 116.001 1.00 29.42 ? 95  LEU C CD1 1 
ATOM   4247 C CD2 . LEU C 3 113 ? 125.279 134.772 114.344 1.00 34.20 ? 95  LEU C CD2 1 
ATOM   4248 N N   . ARG C 3 114 ? 120.830 132.757 115.414 1.00 50.44 ? 96  ARG C N   1 
ATOM   4249 C CA  . ARG C 3 114 ? 119.684 131.912 115.733 1.00 52.48 ? 96  ARG C CA  1 
ATOM   4250 C C   . ARG C 3 114 ? 120.112 130.662 116.492 1.00 55.52 ? 96  ARG C C   1 
ATOM   4251 O O   . ARG C 3 114 ? 119.401 130.205 117.395 1.00 58.02 ? 96  ARG C O   1 
ATOM   4252 C CB  . ARG C 3 114 ? 118.938 131.539 114.454 1.00 52.11 ? 96  ARG C CB  1 
ATOM   4253 C CG  . ARG C 3 114 ? 117.934 132.599 114.016 1.00 54.64 ? 96  ARG C CG  1 
ATOM   4254 C CD  . ARG C 3 114 ? 117.227 132.311 112.681 1.00 56.38 ? 96  ARG C CD  1 
ATOM   4255 N NE  . ARG C 3 114 ? 117.000 130.895 112.390 1.00 59.69 ? 96  ARG C NE  1 
ATOM   4256 C CZ  . ARG C 3 114 ? 116.101 130.427 111.531 1.00 61.06 ? 96  ARG C CZ  1 
ATOM   4257 N NH1 . ARG C 3 114 ? 115.324 131.232 110.818 1.00 58.86 ? 96  ARG C NH1 1 
ATOM   4258 N NH2 . ARG C 3 114 ? 115.978 129.112 111.377 1.00 57.16 ? 96  ARG C NH2 1 
ATOM   4259 N N   . SER C 3 115 ? 121.265 130.096 116.138 1.00 52.74 ? 97  SER C N   1 
ATOM   4260 C CA  . SER C 3 115 ? 121.801 128.891 116.761 1.00 48.55 ? 97  SER C CA  1 
ATOM   4261 C C   . SER C 3 115 ? 123.031 129.249 117.583 1.00 44.62 ? 97  SER C C   1 
ATOM   4262 O O   . SER C 3 115 ? 123.986 129.831 117.060 1.00 45.23 ? 97  SER C O   1 
ATOM   4263 C CB  . SER C 3 115 ? 122.160 127.848 115.702 1.00 49.44 ? 97  SER C CB  1 
ATOM   4264 O OG  . SER C 3 115 ? 122.345 126.570 116.284 1.00 49.16 ? 97  SER C OG  1 
ATOM   4265 N N   . SER C 3 116 ? 123.006 128.890 118.869 1.00 42.01 ? 98  SER C N   1 
ATOM   4266 C CA  . SER C 3 116 ? 124.162 129.120 119.733 1.00 45.42 ? 98  SER C CA  1 
ATOM   4267 C C   . SER C 3 116 ? 125.364 128.284 119.306 1.00 47.02 ? 98  SER C C   1 
ATOM   4268 O O   . SER C 3 116 ? 126.510 128.628 119.619 1.00 43.63 ? 98  SER C O   1 
ATOM   4269 C CB  . SER C 3 116 ? 123.799 128.812 121.184 1.00 47.81 ? 98  SER C CB  1 
ATOM   4270 O OG  . SER C 3 116 ? 124.964 128.587 121.958 1.00 45.82 ? 98  SER C OG  1 
ATOM   4271 N N   . TRP C 3 117 ? 125.125 127.176 118.609 1.00 53.88 ? 99  TRP C N   1 
ATOM   4272 C CA  . TRP C 3 117 ? 126.163 126.213 118.251 1.00 46.07 ? 99  TRP C CA  1 
ATOM   4273 C C   . TRP C 3 117 ? 126.771 126.621 116.918 1.00 48.56 ? 99  TRP C C   1 
ATOM   4274 O O   . TRP C 3 117 ? 126.149 126.457 115.867 1.00 48.94 ? 99  TRP C O   1 
ATOM   4275 C CB  . TRP C 3 117 ? 125.564 124.814 118.204 1.00 45.17 ? 99  TRP C CB  1 
ATOM   4276 C CG  . TRP C 3 117 ? 124.673 124.553 119.378 1.00 54.07 ? 99  TRP C CG  1 
ATOM   4277 C CD1 . TRP C 3 117 ? 123.311 124.499 119.383 1.00 54.08 ? 99  TRP C CD1 1 
ATOM   4278 C CD2 . TRP C 3 117 ? 125.089 124.306 120.722 1.00 53.56 ? 99  TRP C CD2 1 
ATOM   4279 N NE1 . TRP C 3 117 ? 122.853 124.243 120.652 1.00 50.26 ? 99  TRP C NE1 1 
ATOM   4280 C CE2 . TRP C 3 117 ? 123.928 124.118 121.491 1.00 50.93 ? 99  TRP C CE2 1 
ATOM   4281 C CE3 . TRP C 3 117 ? 126.333 124.228 121.349 1.00 50.86 ? 99  TRP C CE3 1 
ATOM   4282 C CZ2 . TRP C 3 117 ? 123.975 123.860 122.855 1.00 52.62 ? 99  TRP C CZ2 1 
ATOM   4283 C CZ3 . TRP C 3 117 ? 126.379 123.971 122.701 1.00 50.98 ? 99  TRP C CZ3 1 
ATOM   4284 C CH2 . TRP C 3 117 ? 125.207 123.787 123.441 1.00 53.07 ? 99  TRP C CH2 1 
ATOM   4285 N N   . VAL C 3 118 ? 127.983 127.172 116.967 1.00 45.16 ? 100 VAL C N   1 
ATOM   4286 C CA  . VAL C 3 118 ? 128.714 127.632 115.789 1.00 40.97 ? 100 VAL C CA  1 
ATOM   4287 C C   . VAL C 3 118 ? 130.152 127.154 115.904 1.00 44.55 ? 100 VAL C C   1 
ATOM   4288 O O   . VAL C 3 118 ? 130.780 127.306 116.959 1.00 43.55 ? 100 VAL C O   1 
ATOM   4289 C CB  . VAL C 3 118 ? 128.650 129.159 115.628 1.00 31.89 ? 100 VAL C CB  1 
ATOM   4290 C CG1 . VAL C 3 118 ? 127.290 129.555 115.118 1.00 38.84 ? 100 VAL C CG1 1 
ATOM   4291 C CG2 . VAL C 3 118 ? 128.949 129.880 116.946 1.00 30.33 ? 100 VAL C CG2 1 
ATOM   4292 N N   . MET C 3 119 ? 130.664 126.569 114.819 1.00 42.21 ? 101 MET C N   1 
ATOM   4293 C CA  . MET C 3 119 ? 132.016 126.031 114.752 1.00 33.73 ? 101 MET C CA  1 
ATOM   4294 C C   . MET C 3 119 ? 132.894 126.713 113.711 1.00 31.91 ? 101 MET C C   1 
ATOM   4295 O O   . MET C 3 119 ? 134.062 126.337 113.582 1.00 35.97 ? 101 MET C O   1 
ATOM   4296 C CB  . MET C 3 119 ? 131.975 124.522 114.463 1.00 39.55 ? 101 MET C CB  1 
ATOM   4297 C CG  . MET C 3 119 ? 131.156 123.683 115.450 1.00 40.79 ? 101 MET C CG  1 
ATOM   4298 S SD  . MET C 3 119 ? 130.373 122.264 114.663 1.00 42.29 ? 101 MET C SD  1 
ATOM   4299 C CE  . MET C 3 119 ? 131.732 121.099 114.606 1.00 36.97 ? 101 MET C CE  1 
ATOM   4300 N N   . THR C 3 120 ? 132.375 127.692 112.967 1.00 29.69 ? 102 THR C N   1 
ATOM   4301 C CA  . THR C 3 120 ? 133.154 128.368 111.939 1.00 30.74 ? 102 THR C CA  1 
ATOM   4302 C C   . THR C 3 120 ? 132.658 129.793 111.752 1.00 31.69 ? 102 THR C C   1 
ATOM   4303 O O   . THR C 3 120 ? 131.495 130.107 112.014 1.00 30.39 ? 102 THR C O   1 
ATOM   4304 C CB  . THR C 3 120 ? 133.091 127.630 110.594 1.00 30.83 ? 102 THR C CB  1 
ATOM   4305 O OG1 . THR C 3 120 ? 133.860 128.353 109.627 1.00 38.33 ? 102 THR C OG1 1 
ATOM   4306 C CG2 . THR C 3 120 ? 131.649 127.483 110.084 1.00 25.40 ? 102 THR C CG2 1 
ATOM   4307 N N   . CYS C 3 121 ? 133.565 130.653 111.295 1.00 36.90 ? 103 CYS C N   1 
ATOM   4308 C CA  . CYS C 3 121 ? 133.231 132.004 110.876 1.00 25.26 ? 103 CYS C CA  1 
ATOM   4309 C C   . CYS C 3 121 ? 134.234 132.444 109.822 1.00 28.66 ? 103 CYS C C   1 
ATOM   4310 O O   . CYS C 3 121 ? 135.376 131.978 109.815 1.00 28.70 ? 103 CYS C O   1 
ATOM   4311 C CB  . CYS C 3 121 ? 133.234 132.983 112.052 1.00 9.76  ? 103 CYS C CB  1 
ATOM   4312 S SG  . CYS C 3 121 ? 134.860 133.590 112.505 1.00 16.38 ? 103 CYS C SG  1 
ATOM   4313 N N   . ALA C 3 122 ? 133.799 133.331 108.929 1.00 25.41 ? 104 ALA C N   1 
ATOM   4314 C CA  . ALA C 3 122 ? 134.639 133.830 107.852 1.00 13.63 ? 104 ALA C CA  1 
ATOM   4315 C C   . ALA C 3 122 ? 134.333 135.297 107.599 1.00 18.36 ? 104 ALA C C   1 
ATOM   4316 O O   . ALA C 3 122 ? 133.249 135.788 107.920 1.00 19.69 ? 104 ALA C O   1 
ATOM   4317 C CB  . ALA C 3 122 ? 134.436 133.031 106.563 1.00 13.08 ? 104 ALA C CB  1 
ATOM   4318 N N   . TYR C 3 123 ? 135.330 135.980 107.023 1.00 28.97 ? 105 TYR C N   1 
ATOM   4319 C CA  . TYR C 3 123 ? 135.186 137.416 106.675 1.00 19.82 ? 105 TYR C CA  1 
ATOM   4320 C C   . TYR C 3 123 ? 135.451 137.537 105.181 1.00 24.90 ? 105 TYR C C   1 
ATOM   4321 O O   . TYR C 3 123 ? 136.493 137.027 104.714 1.00 35.05 ? 105 TYR C O   1 
ATOM   4322 C CB  . TYR C 3 123 ? 136.190 138.197 107.526 1.00 13.41 ? 105 TYR C CB  1 
ATOM   4323 C CG  . TYR C 3 123 ? 136.019 139.710 107.529 1.00 23.60 ? 105 TYR C CG  1 
ATOM   4324 C CD1 . TYR C 3 123 ? 135.260 140.343 108.505 1.00 23.74 ? 105 TYR C CD1 1 
ATOM   4325 C CD2 . TYR C 3 123 ? 136.618 140.502 106.559 1.00 22.86 ? 105 TYR C CD2 1 
ATOM   4326 C CE1 . TYR C 3 123 ? 135.104 141.719 108.517 1.00 21.74 ? 105 TYR C CE1 1 
ATOM   4327 C CE2 . TYR C 3 123 ? 136.472 141.878 106.561 1.00 17.87 ? 105 TYR C CE2 1 
ATOM   4328 C CZ  . TYR C 3 123 ? 135.710 142.489 107.541 1.00 22.22 ? 105 TYR C CZ  1 
ATOM   4329 O OH  . TYR C 3 123 ? 135.560 143.845 107.545 1.00 25.49 ? 105 TYR C OH  1 
ATOM   4330 N N   . ALA C 3 124 ? 134.548 138.183 104.443 1.00 20.27 ? 106 ALA C N   1 
ATOM   4331 C CA  . ALA C 3 124 ? 134.663 138.300 103.001 1.00 17.11 ? 106 ALA C CA  1 
ATOM   4332 C C   . ALA C 3 124 ? 135.940 139.064 102.640 1.00 23.72 ? 106 ALA C C   1 
ATOM   4333 O O   . ALA C 3 124 ? 136.398 139.906 103.416 1.00 25.11 ? 106 ALA C O   1 
ATOM   4334 C CB  . ALA C 3 124 ? 133.451 139.017 102.420 1.00 22.57 ? 106 ALA C CB  1 
ATOM   4335 N N   . PRO C 3 125 ? 136.555 138.775 101.481 1.00 26.16 ? 107 PRO C N   1 
ATOM   4336 C CA  . PRO C 3 125 ? 137.735 139.569 101.091 1.00 18.47 ? 107 PRO C CA  1 
ATOM   4337 C C   . PRO C 3 125 ? 137.437 141.047 100.918 1.00 24.53 ? 107 PRO C C   1 
ATOM   4338 O O   . PRO C 3 125 ? 138.292 141.888 101.216 1.00 28.28 ? 107 PRO C O   1 
ATOM   4339 C CB  . PRO C 3 125 ? 138.173 138.916 99.772  1.00 19.35 ? 107 PRO C CB  1 
ATOM   4340 C CG  . PRO C 3 125 ? 137.590 137.564 99.812  1.00 24.80 ? 107 PRO C CG  1 
ATOM   4341 C CD  . PRO C 3 125 ? 136.269 137.751 100.460 1.00 26.85 ? 107 PRO C CD  1 
ATOM   4342 N N   . SER C 3 126 ? 136.211 141.371 100.493 1.00 30.25 ? 108 SER C N   1 
ATOM   4343 C CA  . SER C 3 126 ? 135.815 142.792 100.293 1.00 21.50 ? 108 SER C CA  1 
ATOM   4344 C C   . SER C 3 126 ? 135.350 143.410 101.619 1.00 25.72 ? 108 SER C C   1 
ATOM   4345 O O   . SER C 3 126 ? 135.149 144.644 101.653 1.00 33.99 ? 108 SER C O   1 
ATOM   4346 C CB  . SER C 3 126 ? 134.743 142.912 99.243  1.00 25.71 ? 108 SER C CB  1 
ATOM   4347 O OG  . SER C 3 126 ? 133.505 142.424 99.741  1.00 25.70 ? 108 SER C OG  1 
ATOM   4348 N N   . GLY C 3 127 ? 135.177 142.592 102.661 1.00 26.10 ? 109 GLY C N   1 
ATOM   4349 C CA  . GLY C 3 127 ? 134.732 143.083 103.946 1.00 17.86 ? 109 GLY C CA  1 
ATOM   4350 C C   . GLY C 3 127 ? 133.262 143.431 104.016 1.00 20.23 ? 109 GLY C C   1 
ATOM   4351 O O   . GLY C 3 127 ? 132.809 143.918 105.058 1.00 27.80 ? 109 GLY C O   1 
ATOM   4352 N N   . ASN C 3 128 ? 132.504 143.206 102.940 1.00 25.01 ? 110 ASN C N   1 
ATOM   4353 C CA  . ASN C 3 128 ? 131.078 143.508 102.957 1.00 28.50 ? 110 ASN C CA  1 
ATOM   4354 C C   . ASN C 3 128 ? 130.295 142.484 103.768 1.00 25.12 ? 110 ASN C C   1 
ATOM   4355 O O   . ASN C 3 128 ? 129.283 142.828 104.388 1.00 23.13 ? 110 ASN C O   1 
ATOM   4356 C CB  . ASN C 3 128 ? 130.540 143.570 101.528 1.00 26.97 ? 110 ASN C CB  1 
ATOM   4357 C CG  . ASN C 3 128 ? 131.253 144.599 100.678 1.00 30.86 ? 110 ASN C CG  1 
ATOM   4358 O OD1 . ASN C 3 128 ? 131.659 145.650 101.166 1.00 32.33 ? 110 ASN C OD1 1 
ATOM   4359 N ND2 . ASN C 3 128 ? 131.413 144.297 99.395  1.00 25.25 ? 110 ASN C ND2 1 
ATOM   4360 N N   . TYR C 3 129 ? 130.740 141.223 103.768 1.00 27.28 ? 111 TYR C N   1 
ATOM   4361 C CA  . TYR C 3 129 ? 129.990 140.114 104.342 1.00 28.98 ? 111 TYR C CA  1 
ATOM   4362 C C   . TYR C 3 129 ? 130.839 139.322 105.325 1.00 27.38 ? 111 TYR C C   1 
ATOM   4363 O O   . TYR C 3 129 ? 132.071 139.338 105.279 1.00 25.79 ? 111 TYR C O   1 
ATOM   4364 C CB  . TYR C 3 129 ? 129.476 139.147 103.261 1.00 30.73 ? 111 TYR C CB  1 
ATOM   4365 C CG  . TYR C 3 129 ? 128.493 139.747 102.286 1.00 26.49 ? 111 TYR C CG  1 
ATOM   4366 C CD1 . TYR C 3 129 ? 128.929 140.427 101.163 1.00 30.23 ? 111 TYR C CD1 1 
ATOM   4367 C CD2 . TYR C 3 129 ? 127.128 139.639 102.495 1.00 24.27 ? 111 TYR C CD2 1 
ATOM   4368 C CE1 . TYR C 3 129 ? 128.037 140.977 100.271 1.00 32.95 ? 111 TYR C CE1 1 
ATOM   4369 C CE2 . TYR C 3 129 ? 126.227 140.187 101.610 1.00 30.26 ? 111 TYR C CE2 1 
ATOM   4370 C CZ  . TYR C 3 129 ? 126.687 140.856 100.499 1.00 32.50 ? 111 TYR C CZ  1 
ATOM   4371 O OH  . TYR C 3 129 ? 125.793 141.407 99.610  1.00 25.17 ? 111 TYR C OH  1 
ATOM   4372 N N   . VAL C 3 130 ? 130.141 138.631 106.225 1.00 29.46 ? 112 VAL C N   1 
ATOM   4373 C CA  . VAL C 3 130 ? 130.704 137.587 107.071 1.00 24.56 ? 112 VAL C CA  1 
ATOM   4374 C C   . VAL C 3 130 ? 129.769 136.389 106.992 1.00 21.39 ? 112 VAL C C   1 
ATOM   4375 O O   . VAL C 3 130 ? 128.586 136.528 106.667 1.00 21.93 ? 112 VAL C O   1 
ATOM   4376 C CB  . VAL C 3 130 ? 130.900 138.040 108.540 1.00 22.52 ? 112 VAL C CB  1 
ATOM   4377 C CG1 . VAL C 3 130 ? 131.939 139.143 108.620 1.00 22.65 ? 112 VAL C CG1 1 
ATOM   4378 C CG2 . VAL C 3 130 ? 129.580 138.486 109.179 1.00 25.07 ? 112 VAL C CG2 1 
ATOM   4379 N N   . ALA C 3 131 ? 130.309 135.206 107.289 1.00 25.77 ? 113 ALA C N   1 
ATOM   4380 C CA  . ALA C 3 131 ? 129.577 133.948 107.225 1.00 15.02 ? 113 ALA C CA  1 
ATOM   4381 C C   . ALA C 3 131 ? 129.714 133.210 108.545 1.00 20.03 ? 113 ALA C C   1 
ATOM   4382 O O   . ALA C 3 131 ? 130.698 133.394 109.264 1.00 25.14 ? 113 ALA C O   1 
ATOM   4383 C CB  . ALA C 3 131 ? 130.085 133.065 106.086 1.00 24.60 ? 113 ALA C CB  1 
ATOM   4384 N N   . CYS C 3 132 ? 128.711 132.395 108.867 1.00 25.11 ? 114 CYS C N   1 
ATOM   4385 C CA  . CYS C 3 132 ? 128.695 131.586 110.077 1.00 19.50 ? 114 CYS C CA  1 
ATOM   4386 C C   . CYS C 3 132 ? 128.110 130.214 109.783 1.00 33.08 ? 114 CYS C C   1 
ATOM   4387 O O   . CYS C 3 132 ? 127.147 130.094 109.023 1.00 41.81 ? 114 CYS C O   1 
ATOM   4388 C CB  . CYS C 3 132 ? 127.885 132.257 111.180 1.00 20.82 ? 114 CYS C CB  1 
ATOM   4389 S SG  . CYS C 3 132 ? 128.520 131.922 112.818 1.00 60.27 ? 114 CYS C SG  1 
ATOM   4390 N N   . GLY C 3 133 ? 128.696 129.191 110.396 1.00 39.85 ? 115 GLY C N   1 
ATOM   4391 C CA  . GLY C 3 133 ? 128.203 127.833 110.269 1.00 36.42 ? 115 GLY C CA  1 
ATOM   4392 C C   . GLY C 3 133 ? 128.296 127.109 111.594 1.00 34.05 ? 115 GLY C C   1 
ATOM   4393 O O   . GLY C 3 133 ? 129.031 127.509 112.494 1.00 37.26 ? 115 GLY C O   1 
ATOM   4394 N N   . GLY C 3 134 ? 127.529 126.028 111.707 1.00 38.02 ? 116 GLY C N   1 
ATOM   4395 C CA  . GLY C 3 134 ? 127.451 125.329 112.977 1.00 40.39 ? 116 GLY C CA  1 
ATOM   4396 C C   . GLY C 3 134 ? 126.719 124.012 112.871 1.00 39.70 ? 116 GLY C C   1 
ATOM   4397 O O   . GLY C 3 134 ? 126.513 123.469 111.785 1.00 36.13 ? 116 GLY C O   1 
ATOM   4398 N N   . LEU C 3 135 ? 126.319 123.501 114.041 1.00 47.43 ? 117 LEU C N   1 
ATOM   4399 C CA  . LEU C 3 135 ? 125.604 122.229 114.103 1.00 47.61 ? 117 LEU C CA  1 
ATOM   4400 C C   . LEU C 3 135 ? 124.228 122.289 113.445 1.00 44.88 ? 117 LEU C C   1 
ATOM   4401 O O   . LEU C 3 135 ? 123.641 121.235 113.178 1.00 47.55 ? 117 LEU C O   1 
ATOM   4402 C CB  . LEU C 3 135 ? 125.453 121.768 115.560 1.00 48.07 ? 117 LEU C CB  1 
ATOM   4403 C CG  . LEU C 3 135 ? 126.667 121.135 116.257 1.00 41.92 ? 117 LEU C CG  1 
ATOM   4404 C CD1 . LEU C 3 135 ? 126.466 121.042 117.770 1.00 45.05 ? 117 LEU C CD1 1 
ATOM   4405 C CD2 . LEU C 3 135 ? 126.981 119.759 115.701 1.00 43.25 ? 117 LEU C CD2 1 
ATOM   4406 N N   . ASP C 3 136 ? 123.695 123.486 113.179 1.00 46.53 ? 118 ASP C N   1 
ATOM   4407 C CA  . ASP C 3 136 ? 122.421 123.593 112.462 1.00 46.19 ? 118 ASP C CA  1 
ATOM   4408 C C   . ASP C 3 136 ? 122.549 123.199 110.988 1.00 45.40 ? 118 ASP C C   1 
ATOM   4409 O O   . ASP C 3 136 ? 121.538 123.132 110.279 1.00 45.66 ? 118 ASP C O   1 
ATOM   4410 C CB  . ASP C 3 136 ? 121.835 125.009 112.571 1.00 46.69 ? 118 ASP C CB  1 
ATOM   4411 C CG  . ASP C 3 136 ? 122.837 126.107 112.239 1.00 51.71 ? 118 ASP C CG  1 
ATOM   4412 O OD1 . ASP C 3 136 ? 123.897 126.165 112.894 1.00 52.85 ? 118 ASP C OD1 1 
ATOM   4413 O OD2 . ASP C 3 136 ? 122.559 126.914 111.328 1.00 50.99 ? 118 ASP C OD2 1 
ATOM   4414 N N   . ASN C 3 137 ? 123.778 122.995 110.493 1.00 41.50 ? 119 ASN C N   1 
ATOM   4415 C CA  . ASN C 3 137 ? 124.064 122.513 109.140 1.00 39.84 ? 119 ASN C CA  1 
ATOM   4416 C C   . ASN C 3 137 ? 123.800 123.568 108.071 1.00 43.07 ? 119 ASN C C   1 
ATOM   4417 O O   . ASN C 3 137 ? 123.750 123.235 106.883 1.00 46.25 ? 119 ASN C O   1 
ATOM   4418 C CB  . ASN C 3 137 ? 123.255 121.255 108.789 1.00 41.65 ? 119 ASN C CB  1 
ATOM   4419 C CG  . ASN C 3 137 ? 123.306 120.195 109.867 1.00 44.19 ? 119 ASN C CG  1 
ATOM   4420 O OD1 . ASN C 3 137 ? 124.311 120.028 110.549 1.00 44.43 ? 119 ASN C OD1 1 
ATOM   4421 N ND2 . ASN C 3 137 ? 122.225 119.441 109.995 1.00 46.28 ? 119 ASN C ND2 1 
ATOM   4422 N N   . ILE C 3 138 ? 123.633 124.829 108.472 1.00 42.93 ? 120 ILE C N   1 
ATOM   4423 C CA  . ILE C 3 138 ? 123.286 125.926 107.573 1.00 38.07 ? 120 ILE C CA  1 
ATOM   4424 C C   . ILE C 3 138 ? 124.393 126.965 107.645 1.00 39.48 ? 120 ILE C C   1 
ATOM   4425 O O   . ILE C 3 138 ? 124.877 127.293 108.735 1.00 39.38 ? 120 ILE C O   1 
ATOM   4426 C CB  . ILE C 3 138 ? 121.923 126.557 107.934 1.00 33.04 ? 120 ILE C CB  1 
ATOM   4427 C CG1 . ILE C 3 138 ? 120.778 125.539 107.838 1.00 35.05 ? 120 ILE C CG1 1 
ATOM   4428 C CG2 . ILE C 3 138 ? 121.632 127.754 107.044 1.00 34.75 ? 120 ILE C CG2 1 
ATOM   4429 C CD1 . ILE C 3 138 ? 119.671 125.794 108.829 1.00 37.53 ? 120 ILE C CD1 1 
ATOM   4430 N N   . CYS C 3 139 ? 124.802 127.471 106.483 1.00 33.16 ? 121 CYS C N   1 
ATOM   4431 C CA  . CYS C 3 139 ? 125.734 128.586 106.389 1.00 27.41 ? 121 CYS C CA  1 
ATOM   4432 C C   . CYS C 3 139 ? 124.937 129.872 106.228 1.00 32.88 ? 121 CYS C C   1 
ATOM   4433 O O   . CYS C 3 139 ? 124.266 130.063 105.210 1.00 42.64 ? 121 CYS C O   1 
ATOM   4434 C CB  . CYS C 3 139 ? 126.689 128.413 105.209 1.00 29.10 ? 121 CYS C CB  1 
ATOM   4435 S SG  . CYS C 3 139 ? 128.136 129.487 105.253 1.00 42.30 ? 121 CYS C SG  1 
ATOM   4436 N N   . SER C 3 140 ? 125.023 130.749 107.224 1.00 23.48 ? 122 SER C N   1 
ATOM   4437 C CA  . SER C 3 140 ? 124.294 132.010 107.242 1.00 18.83 ? 122 SER C CA  1 
ATOM   4438 C C   . SER C 3 140 ? 125.254 133.134 106.891 1.00 31.94 ? 122 SER C C   1 
ATOM   4439 O O   . SER C 3 140 ? 126.318 133.255 107.504 1.00 36.59 ? 122 SER C O   1 
ATOM   4440 C CB  . SER C 3 140 ? 123.665 132.263 108.611 1.00 26.39 ? 122 SER C CB  1 
ATOM   4441 O OG  . SER C 3 140 ? 122.951 131.129 109.063 1.00 34.44 ? 122 SER C OG  1 
ATOM   4442 N N   . ILE C 3 141 ? 124.872 133.948 105.910 1.00 39.09 ? 123 ILE C N   1 
ATOM   4443 C CA  . ILE C 3 141 ? 125.698 135.032 105.390 1.00 32.30 ? 123 ILE C CA  1 
ATOM   4444 C C   . ILE C 3 141 ? 125.023 136.344 105.758 1.00 34.93 ? 123 ILE C C   1 
ATOM   4445 O O   . ILE C 3 141 ? 123.810 136.498 105.575 1.00 34.91 ? 123 ILE C O   1 
ATOM   4446 C CB  . ILE C 3 141 ? 125.905 134.894 103.871 1.00 20.89 ? 123 ILE C CB  1 
ATOM   4447 C CG1 . ILE C 3 141 ? 126.656 133.572 103.619 1.00 22.76 ? 123 ILE C CG1 1 
ATOM   4448 C CG2 . ILE C 3 141 ? 126.618 136.164 103.303 1.00 35.55 ? 123 ILE C CG2 1 
ATOM   4449 C CD1 . ILE C 3 141 ? 127.208 133.354 102.248 1.00 31.19 ? 123 ILE C CD1 1 
ATOM   4450 N N   . TYR C 3 142 ? 125.814 137.282 106.273 1.00 27.54 ? 124 TYR C N   1 
ATOM   4451 C CA  . TYR C 3 142 ? 125.327 138.530 106.841 1.00 20.96 ? 124 TYR C CA  1 
ATOM   4452 C C   . TYR C 3 142 ? 125.849 139.693 106.014 1.00 23.92 ? 124 TYR C C   1 
ATOM   4453 O O   . TYR C 3 142 ? 127.026 139.709 105.647 1.00 24.92 ? 124 TYR C O   1 
ATOM   4454 C CB  . TYR C 3 142 ? 125.791 138.670 108.289 1.00 25.60 ? 124 TYR C CB  1 
ATOM   4455 C CG  . TYR C 3 142 ? 125.272 137.583 109.196 1.00 27.59 ? 124 TYR C CG  1 
ATOM   4456 C CD1 . TYR C 3 142 ? 124.025 137.683 109.789 1.00 30.98 ? 124 TYR C CD1 1 
ATOM   4457 C CD2 . TYR C 3 142 ? 126.030 136.450 109.454 1.00 24.23 ? 124 TYR C CD2 1 
ATOM   4458 C CE1 . TYR C 3 142 ? 123.550 136.690 110.615 1.00 30.21 ? 124 TYR C CE1 1 
ATOM   4459 C CE2 . TYR C 3 142 ? 125.563 135.453 110.277 1.00 20.43 ? 124 TYR C CE2 1 
ATOM   4460 C CZ  . TYR C 3 142 ? 124.320 135.578 110.854 1.00 26.63 ? 124 TYR C CZ  1 
ATOM   4461 O OH  . TYR C 3 142 ? 123.839 134.590 111.678 1.00 36.19 ? 124 TYR C OH  1 
ATOM   4462 N N   . ASN C 3 143 ? 124.976 140.655 105.718 1.00 31.43 ? 125 ASN C N   1 
ATOM   4463 C CA  . ASN C 3 143 ? 125.354 141.874 105.006 1.00 25.31 ? 125 ASN C CA  1 
ATOM   4464 C C   . ASN C 3 143 ? 125.716 142.940 106.034 1.00 27.45 ? 125 ASN C C   1 
ATOM   4465 O O   . ASN C 3 143 ? 124.836 143.493 106.700 1.00 32.66 ? 125 ASN C O   1 
ATOM   4466 C CB  . ASN C 3 143 ? 124.216 142.344 104.104 1.00 23.37 ? 125 ASN C CB  1 
ATOM   4467 C CG  . ASN C 3 143 ? 124.668 143.353 103.066 1.00 32.74 ? 125 ASN C CG  1 
ATOM   4468 O OD1 . ASN C 3 143 ? 125.845 143.700 102.988 1.00 41.05 ? 125 ASN C OD1 1 
ATOM   4469 N ND2 . ASN C 3 143 ? 123.728 143.831 102.263 1.00 33.06 ? 125 ASN C ND2 1 
ATOM   4470 N N   . LEU C 3 144 ? 127.014 143.224 106.173 1.00 28.58 ? 126 LEU C N   1 
ATOM   4471 C CA  . LEU C 3 144 ? 127.455 144.160 107.201 1.00 21.71 ? 126 LEU C CA  1 
ATOM   4472 C C   . LEU C 3 144 ? 127.128 145.598 106.827 1.00 24.08 ? 126 LEU C C   1 
ATOM   4473 O O   . LEU C 3 144 ? 126.650 146.368 107.668 1.00 22.70 ? 126 LEU C O   1 
ATOM   4474 C CB  . LEU C 3 144 ? 128.956 144.014 107.440 1.00 19.38 ? 126 LEU C CB  1 
ATOM   4475 C CG  . LEU C 3 144 ? 129.486 142.719 108.058 1.00 14.16 ? 126 LEU C CG  1 
ATOM   4476 C CD1 . LEU C 3 144 ? 130.994 142.822 108.201 1.00 20.25 ? 126 LEU C CD1 1 
ATOM   4477 C CD2 . LEU C 3 144 ? 128.843 142.404 109.398 1.00 17.23 ? 126 LEU C CD2 1 
ATOM   4478 N N   . LYS C 3 145 ? 127.379 145.978 105.577 1.00 27.67 ? 127 LYS C N   1 
ATOM   4479 C CA  . LYS C 3 145 ? 127.168 147.340 105.101 1.00 29.63 ? 127 LYS C CA  1 
ATOM   4480 C C   . LYS C 3 145 ? 125.808 147.408 104.425 1.00 25.09 ? 127 LYS C C   1 
ATOM   4481 O O   . LYS C 3 145 ? 125.628 146.866 103.330 1.00 23.91 ? 127 LYS C O   1 
ATOM   4482 C CB  . LYS C 3 145 ? 128.271 147.768 104.130 1.00 26.66 ? 127 LYS C CB  1 
ATOM   4483 C CG  . LYS C 3 145 ? 129.691 147.702 104.692 1.00 21.42 ? 127 LYS C CG  1 
ATOM   4484 C CD  . LYS C 3 145 ? 130.719 147.819 103.584 1.00 26.56 ? 127 LYS C CD  1 
ATOM   4485 C CE  . LYS C 3 145 ? 132.139 147.828 104.124 1.00 29.34 ? 127 LYS C CE  1 
ATOM   4486 N NZ  . LYS C 3 145 ? 133.153 147.819 103.030 1.00 29.06 ? 127 LYS C NZ  1 
ATOM   4487 N N   . THR C 3 146 ? 124.860 148.078 105.078 1.00 27.32 ? 128 THR C N   1 
ATOM   4488 C CA  . THR C 3 146 ? 123.506 148.234 104.572 1.00 31.93 ? 128 THR C CA  1 
ATOM   4489 C C   . THR C 3 146 ? 123.011 149.635 104.888 1.00 31.65 ? 128 THR C C   1 
ATOM   4490 O O   . THR C 3 146 ? 123.365 150.217 105.916 1.00 35.70 ? 128 THR C O   1 
ATOM   4491 C CB  . THR C 3 146 ? 122.519 147.232 105.202 1.00 34.90 ? 128 THR C CB  1 
ATOM   4492 O OG1 . THR C 3 146 ? 122.281 147.588 106.569 1.00 27.21 ? 128 THR C OG1 1 
ATOM   4493 C CG2 . THR C 3 146 ? 123.045 145.816 105.149 1.00 37.70 ? 128 THR C CG2 1 
ATOM   4494 N N   . ARG C 3 147 ? 122.183 150.168 103.997 1.00 32.95 ? 129 ARG C N   1 
ATOM   4495 C CA  . ARG C 3 147 ? 121.254 151.204 104.409 1.00 24.31 ? 129 ARG C CA  1 
ATOM   4496 C C   . ARG C 3 147 ? 120.290 150.591 105.411 1.00 31.56 ? 129 ARG C C   1 
ATOM   4497 O O   . ARG C 3 147 ? 119.960 149.409 105.324 1.00 46.25 ? 129 ARG C O   1 
ATOM   4498 C CB  . ARG C 3 147 ? 120.482 151.771 103.215 1.00 28.38 ? 129 ARG C CB  1 
ATOM   4499 C CG  . ARG C 3 147 ? 121.334 152.383 102.104 1.00 37.02 ? 129 ARG C CG  1 
ATOM   4500 C CD  . ARG C 3 147 ? 121.919 153.739 102.485 1.00 39.94 ? 129 ARG C CD  1 
ATOM   4501 N NE  . ARG C 3 147 ? 121.049 154.845 102.092 1.00 41.82 ? 129 ARG C NE  1 
ATOM   4502 C CZ  . ARG C 3 147 ? 121.254 156.123 102.391 1.00 37.82 ? 129 ARG C CZ  1 
ATOM   4503 N NH1 . ARG C 3 147 ? 122.307 156.517 103.092 1.00 35.15 ? 129 ARG C NH1 1 
ATOM   4504 N NH2 . ARG C 3 147 ? 120.381 157.034 101.972 1.00 28.44 ? 129 ARG C NH2 1 
ATOM   4505 N N   . GLU C 3 148 ? 119.826 151.416 106.346 1.00 33.12 ? 130 GLU C N   1 
ATOM   4506 C CA  . GLU C 3 148 ? 119.069 151.111 107.570 1.00 34.03 ? 130 GLU C CA  1 
ATOM   4507 C C   . GLU C 3 148 ? 119.995 150.688 108.712 1.00 30.40 ? 130 GLU C C   1 
ATOM   4508 O O   . GLU C 3 148 ? 119.506 150.470 109.821 1.00 33.34 ? 130 GLU C O   1 
ATOM   4509 C CB  . GLU C 3 148 ? 117.969 150.043 107.376 1.00 22.42 ? 130 GLU C CB  1 
ATOM   4510 C CG  . GLU C 3 148 ? 118.346 148.563 107.624 1.00 29.54 ? 130 GLU C CG  1 
ATOM   4511 C CD  . GLU C 3 148 ? 117.533 147.561 106.808 1.00 44.37 ? 130 GLU C CD  1 
ATOM   4512 O OE1 . GLU C 3 148 ? 116.829 147.948 105.851 1.00 38.19 ? 130 GLU C OE1 1 
ATOM   4513 O OE2 . GLU C 3 148 ? 117.604 146.356 107.134 1.00 43.67 ? 130 GLU C OE2 1 
ATOM   4514 N N   . GLY C 3 149 ? 121.301 150.579 108.482 1.00 36.23 ? 131 GLY C N   1 
ATOM   4515 C CA  . GLY C 3 149 ? 122.281 150.542 109.560 1.00 33.10 ? 131 GLY C CA  1 
ATOM   4516 C C   . GLY C 3 149 ? 122.181 149.386 110.531 1.00 38.28 ? 131 GLY C C   1 
ATOM   4517 O O   . GLY C 3 149 ? 122.403 149.578 111.733 1.00 43.73 ? 131 GLY C O   1 
ATOM   4518 N N   . ASN C 3 150 ? 121.862 148.188 110.043 1.00 35.38 ? 132 ASN C N   1 
ATOM   4519 C CA  . ASN C 3 150 ? 121.904 146.979 110.853 1.00 28.00 ? 132 ASN C CA  1 
ATOM   4520 C C   . ASN C 3 150 ? 122.482 145.840 110.028 1.00 35.68 ? 132 ASN C C   1 
ATOM   4521 O O   . ASN C 3 150 ? 122.519 145.902 108.796 1.00 44.27 ? 132 ASN C O   1 
ATOM   4522 C CB  . ASN C 3 150 ? 120.514 146.591 111.387 1.00 29.64 ? 132 ASN C CB  1 
ATOM   4523 C CG  . ASN C 3 150 ? 119.454 146.535 110.303 1.00 38.92 ? 132 ASN C CG  1 
ATOM   4524 O OD1 . ASN C 3 150 ? 119.759 146.442 109.116 1.00 42.21 ? 132 ASN C OD1 1 
ATOM   4525 N ND2 . ASN C 3 150 ? 118.194 146.592 110.713 1.00 39.91 ? 132 ASN C ND2 1 
ATOM   4526 N N   . VAL C 3 151 ? 122.931 144.798 110.721 1.00 28.99 ? 133 VAL C N   1 
ATOM   4527 C CA  . VAL C 3 151 ? 123.460 143.594 110.093 1.00 25.42 ? 133 VAL C CA  1 
ATOM   4528 C C   . VAL C 3 151 ? 122.310 142.610 109.934 1.00 32.23 ? 133 VAL C C   1 
ATOM   4529 O O   . VAL C 3 151 ? 121.685 142.213 110.925 1.00 38.75 ? 133 VAL C O   1 
ATOM   4530 C CB  . VAL C 3 151 ? 124.601 142.987 110.928 1.00 24.92 ? 133 VAL C CB  1 
ATOM   4531 C CG1 . VAL C 3 151 ? 125.105 141.711 110.286 1.00 26.89 ? 133 VAL C CG1 1 
ATOM   4532 C CG2 . VAL C 3 151 ? 125.737 143.993 111.103 1.00 25.40 ? 133 VAL C CG2 1 
ATOM   4533 N N   . ARG C 3 152 ? 122.030 142.221 108.689 1.00 33.25 ? 134 ARG C N   1 
ATOM   4534 C CA  . ARG C 3 152 ? 120.909 141.354 108.350 1.00 37.19 ? 134 ARG C CA  1 
ATOM   4535 C C   . ARG C 3 152 ? 121.400 140.169 107.533 1.00 33.52 ? 134 ARG C C   1 
ATOM   4536 O O   . ARG C 3 152 ? 122.461 140.213 106.908 1.00 36.75 ? 134 ARG C O   1 
ATOM   4537 C CB  . ARG C 3 152 ? 119.820 142.114 107.574 1.00 37.43 ? 134 ARG C CB  1 
ATOM   4538 C CG  . ARG C 3 152 ? 120.307 142.843 106.328 1.00 42.67 ? 134 ARG C CG  1 
ATOM   4539 C CD  . ARG C 3 152 ? 119.143 143.373 105.510 1.00 42.77 ? 134 ARG C CD  1 
ATOM   4540 N NE  . ARG C 3 152 ? 119.507 144.580 104.772 1.00 47.34 ? 134 ARG C NE  1 
ATOM   4541 C CZ  . ARG C 3 152 ? 118.984 144.969 103.614 1.00 48.65 ? 134 ARG C CZ  1 
ATOM   4542 N NH1 . ARG C 3 152 ? 118.006 144.299 103.022 1.00 41.24 ? 134 ARG C NH1 1 
ATOM   4543 N NH2 . ARG C 3 152 ? 119.451 146.071 103.033 1.00 41.69 ? 134 ARG C NH2 1 
ATOM   4544 N N   . VAL C 3 153 ? 120.600 139.108 107.536 1.00 38.46 ? 135 VAL C N   1 
ATOM   4545 C CA  . VAL C 3 153 ? 120.959 137.851 106.888 1.00 38.65 ? 135 VAL C CA  1 
ATOM   4546 C C   . VAL C 3 153 ? 120.738 138.016 105.389 1.00 36.36 ? 135 VAL C C   1 
ATOM   4547 O O   . VAL C 3 153 ? 119.601 138.145 104.929 1.00 40.06 ? 135 VAL C O   1 
ATOM   4548 C CB  . VAL C 3 153 ? 120.141 136.677 107.440 1.00 32.75 ? 135 VAL C CB  1 
ATOM   4549 C CG1 . VAL C 3 153 ? 120.666 135.352 106.887 1.00 32.17 ? 135 VAL C CG1 1 
ATOM   4550 C CG2 . VAL C 3 153 ? 120.155 136.685 108.961 1.00 33.21 ? 135 VAL C CG2 1 
ATOM   4551 N N   . SER C 3 154 ? 121.830 138.016 104.625 1.00 32.61 ? 136 SER C N   1 
ATOM   4552 C CA  . SER C 3 154 ? 121.712 138.041 103.173 1.00 35.20 ? 136 SER C CA  1 
ATOM   4553 C C   . SER C 3 154 ? 121.194 136.710 102.643 1.00 39.93 ? 136 SER C C   1 
ATOM   4554 O O   . SER C 3 154 ? 120.357 136.679 101.734 1.00 36.60 ? 136 SER C O   1 
ATOM   4555 C CB  . SER C 3 154 ? 123.064 138.379 102.547 1.00 32.33 ? 136 SER C CB  1 
ATOM   4556 O OG  . SER C 3 154 ? 122.975 138.418 101.136 1.00 36.79 ? 136 SER C OG  1 
ATOM   4557 N N   . ARG C 3 155 ? 121.683 135.600 103.196 1.00 44.24 ? 137 ARG C N   1 
ATOM   4558 C CA  . ARG C 3 155 ? 121.316 134.271 102.732 1.00 36.18 ? 137 ARG C CA  1 
ATOM   4559 C C   . ARG C 3 155 ? 121.492 133.269 103.862 1.00 36.85 ? 137 ARG C C   1 
ATOM   4560 O O   . ARG C 3 155 ? 122.344 133.442 104.737 1.00 39.86 ? 137 ARG C O   1 
ATOM   4561 C CB  . ARG C 3 155 ? 122.176 133.841 101.533 1.00 32.12 ? 137 ARG C CB  1 
ATOM   4562 C CG  . ARG C 3 155 ? 121.498 132.964 100.472 1.00 38.19 ? 137 ARG C CG  1 
ATOM   4563 C CD  . ARG C 3 155 ? 120.303 133.610 99.769  1.00 45.98 ? 137 ARG C CD  1 
ATOM   4564 N NE  . ARG C 3 155 ? 120.675 134.830 99.061  1.00 48.37 ? 137 ARG C NE  1 
ATOM   4565 C CZ  . ARG C 3 155 ? 119.822 135.701 98.534  1.00 44.17 ? 137 ARG C CZ  1 
ATOM   4566 N NH1 . ARG C 3 155 ? 118.510 135.539 98.625  1.00 39.83 ? 137 ARG C NH1 1 
ATOM   4567 N NH2 . ARG C 3 155 ? 120.298 136.765 97.894  1.00 45.74 ? 137 ARG C NH2 1 
ATOM   4568 N N   . GLU C 3 156 ? 120.669 132.224 103.832 1.00 39.55 ? 138 GLU C N   1 
ATOM   4569 C CA  . GLU C 3 156 ? 120.875 131.010 104.612 1.00 37.10 ? 138 GLU C CA  1 
ATOM   4570 C C   . GLU C 3 156 ? 120.973 129.850 103.637 1.00 36.27 ? 138 GLU C C   1 
ATOM   4571 O O   . GLU C 3 156 ? 120.003 129.541 102.938 1.00 36.13 ? 138 GLU C O   1 
ATOM   4572 C CB  . GLU C 3 156 ? 119.739 130.775 105.610 1.00 34.17 ? 138 GLU C CB  1 
ATOM   4573 C CG  . GLU C 3 156 ? 119.529 131.921 106.590 1.00 41.11 ? 138 GLU C CG  1 
ATOM   4574 C CD  . GLU C 3 156 ? 118.616 131.561 107.750 1.00 46.44 ? 138 GLU C CD  1 
ATOM   4575 O OE1 . GLU C 3 156 ? 117.932 132.470 108.265 1.00 45.30 ? 138 GLU C OE1 1 
ATOM   4576 O OE2 . GLU C 3 156 ? 118.582 130.381 108.157 1.00 41.37 ? 138 GLU C OE2 1 
ATOM   4577 N N   . LEU C 3 157 ? 122.134 129.205 103.600 1.00 34.93 ? 139 LEU C N   1 
ATOM   4578 C CA  . LEU C 3 157 ? 122.462 128.224 102.577 1.00 32.08 ? 139 LEU C CA  1 
ATOM   4579 C C   . LEU C 3 157 ? 122.239 126.827 103.136 1.00 37.33 ? 139 LEU C C   1 
ATOM   4580 O O   . LEU C 3 157 ? 122.917 126.421 104.085 1.00 36.75 ? 139 LEU C O   1 
ATOM   4581 C CB  . LEU C 3 157 ? 123.915 128.383 102.124 1.00 29.53 ? 139 LEU C CB  1 
ATOM   4582 C CG  . LEU C 3 157 ? 124.291 129.698 101.433 1.00 29.74 ? 139 LEU C CG  1 
ATOM   4583 C CD1 . LEU C 3 157 ? 125.795 129.786 101.241 1.00 26.39 ? 139 LEU C CD1 1 
ATOM   4584 C CD2 . LEU C 3 157 ? 123.580 129.854 100.104 1.00 37.69 ? 139 LEU C CD2 1 
ATOM   4585 N N   . ALA C 3 158 ? 121.305 126.094 102.530 1.00 36.20 ? 140 ALA C N   1 
ATOM   4586 C CA  . ALA C 3 158 ? 120.921 124.760 102.965 1.00 28.09 ? 140 ALA C CA  1 
ATOM   4587 C C   . ALA C 3 158 ? 121.245 123.761 101.865 1.00 29.82 ? 140 ALA C C   1 
ATOM   4588 O O   . ALA C 3 158 ? 121.303 124.106 100.682 1.00 28.34 ? 140 ALA C O   1 
ATOM   4589 C CB  . ALA C 3 158 ? 119.429 124.694 103.314 1.00 25.98 ? 140 ALA C CB  1 
ATOM   4590 N N   . GLY C 3 159 ? 121.437 122.509 102.277 1.00 29.54 ? 141 GLY C N   1 
ATOM   4591 C CA  . GLY C 3 159 ? 121.868 121.442 101.397 1.00 31.28 ? 141 GLY C CA  1 
ATOM   4592 C C   . GLY C 3 159 ? 122.991 120.573 101.925 1.00 25.38 ? 141 GLY C C   1 
ATOM   4593 O O   . GLY C 3 159 ? 123.463 119.697 101.191 1.00 29.27 ? 141 GLY C O   1 
ATOM   4594 N N   . HIS C 3 160 ? 123.434 120.785 103.162 1.00 27.74 ? 142 HIS C N   1 
ATOM   4595 C CA  . HIS C 3 160 ? 124.407 119.933 103.831 1.00 31.12 ? 142 HIS C CA  1 
ATOM   4596 C C   . HIS C 3 160 ? 123.672 119.103 104.873 1.00 34.93 ? 142 HIS C C   1 
ATOM   4597 O O   . HIS C 3 160 ? 122.932 119.652 105.695 1.00 37.19 ? 142 HIS C O   1 
ATOM   4598 C CB  . HIS C 3 160 ? 125.503 120.772 104.496 1.00 32.22 ? 142 HIS C CB  1 
ATOM   4599 C CG  . HIS C 3 160 ? 126.740 120.930 103.667 1.00 34.96 ? 142 HIS C CG  1 
ATOM   4600 N ND1 . HIS C 3 160 ? 127.547 119.869 103.318 1.00 44.12 ? 142 HIS C ND1 1 
ATOM   4601 C CD2 . HIS C 3 160 ? 127.312 122.030 103.121 1.00 30.63 ? 142 HIS C CD2 1 
ATOM   4602 C CE1 . HIS C 3 160 ? 128.559 120.307 102.592 1.00 35.16 ? 142 HIS C CE1 1 
ATOM   4603 N NE2 . HIS C 3 160 ? 128.441 121.615 102.459 1.00 22.84 ? 142 HIS C NE2 1 
ATOM   4604 N N   . THR C 3 161 ? 123.869 117.787 104.835 1.00 38.93 ? 143 THR C N   1 
ATOM   4605 C CA  . THR C 3 161 ? 123.251 116.883 105.797 1.00 38.53 ? 143 THR C CA  1 
ATOM   4606 C C   . THR C 3 161 ? 124.073 116.712 107.069 1.00 40.19 ? 143 THR C C   1 
ATOM   4607 O O   . THR C 3 161 ? 123.725 115.863 107.896 1.00 40.83 ? 143 THR C O   1 
ATOM   4608 C CB  . THR C 3 161 ? 123.012 115.509 105.162 1.00 39.07 ? 143 THR C CB  1 
ATOM   4609 O OG1 . THR C 3 161 ? 124.263 114.837 104.980 1.00 47.40 ? 143 THR C OG1 1 
ATOM   4610 C CG2 . THR C 3 161 ? 122.315 115.650 103.819 1.00 41.80 ? 143 THR C CG2 1 
ATOM   4611 N N   . GLY C 3 162 ? 125.157 117.477 107.235 1.00 39.54 ? 144 GLY C N   1 
ATOM   4612 C CA  . GLY C 3 162 ? 125.953 117.425 108.439 1.00 33.03 ? 144 GLY C CA  1 
ATOM   4613 C C   . GLY C 3 162 ? 126.413 118.813 108.837 1.00 35.86 ? 144 GLY C C   1 
ATOM   4614 O O   . GLY C 3 162 ? 126.278 119.780 108.089 1.00 41.67 ? 144 GLY C O   1 
ATOM   4615 N N   . TYR C 3 163 ? 126.957 118.891 110.049 1.00 37.73 ? 145 TYR C N   1 
ATOM   4616 C CA  . TYR C 3 163 ? 127.416 120.161 110.601 1.00 34.74 ? 145 TYR C CA  1 
ATOM   4617 C C   . TYR C 3 163 ? 128.534 120.752 109.756 1.00 36.84 ? 145 TYR C C   1 
ATOM   4618 O O   . TYR C 3 163 ? 129.376 120.026 109.227 1.00 46.29 ? 145 TYR C O   1 
ATOM   4619 C CB  . TYR C 3 163 ? 127.884 119.963 112.045 1.00 32.22 ? 145 TYR C CB  1 
ATOM   4620 C CG  . TYR C 3 163 ? 128.987 118.940 112.253 1.00 33.41 ? 145 TYR C CG  1 
ATOM   4621 C CD1 . TYR C 3 163 ? 130.324 119.257 112.039 1.00 34.23 ? 145 TYR C CD1 1 
ATOM   4622 C CD2 . TYR C 3 163 ? 128.683 117.650 112.662 1.00 41.81 ? 145 TYR C CD2 1 
ATOM   4623 C CE1 . TYR C 3 163 ? 131.319 118.325 112.229 1.00 35.24 ? 145 TYR C CE1 1 
ATOM   4624 C CE2 . TYR C 3 163 ? 129.673 116.711 112.852 1.00 44.03 ? 145 TYR C CE2 1 
ATOM   4625 C CZ  . TYR C 3 163 ? 130.988 117.053 112.633 1.00 43.68 ? 145 TYR C CZ  1 
ATOM   4626 O OH  . TYR C 3 163 ? 131.973 116.117 112.827 1.00 39.98 ? 145 TYR C OH  1 
ATOM   4627 N N   . LEU C 3 164 ? 128.550 122.080 109.653 1.00 38.24 ? 146 LEU C N   1 
ATOM   4628 C CA  . LEU C 3 164 ? 129.551 122.795 108.865 1.00 35.24 ? 146 LEU C CA  1 
ATOM   4629 C C   . LEU C 3 164 ? 130.748 123.109 109.752 1.00 31.43 ? 146 LEU C C   1 
ATOM   4630 O O   . LEU C 3 164 ? 130.627 123.861 110.723 1.00 36.14 ? 146 LEU C O   1 
ATOM   4631 C CB  . LEU C 3 164 ? 128.976 124.079 108.278 1.00 33.36 ? 146 LEU C CB  1 
ATOM   4632 C CG  . LEU C 3 164 ? 128.575 124.000 106.809 1.00 31.34 ? 146 LEU C CG  1 
ATOM   4633 C CD1 . LEU C 3 164 ? 127.310 123.177 106.649 1.00 35.64 ? 146 LEU C CD1 1 
ATOM   4634 C CD2 . LEU C 3 164 ? 128.409 125.382 106.245 1.00 30.64 ? 146 LEU C CD2 1 
ATOM   4635 N N   . SER C 3 165 ? 131.904 122.535 109.410 1.00 22.85 ? 147 SER C N   1 
ATOM   4636 C CA  . SER C 3 165 ? 133.105 122.726 110.218 1.00 25.85 ? 147 SER C CA  1 
ATOM   4637 C C   . SER C 3 165 ? 133.933 123.917 109.739 1.00 26.72 ? 147 SER C C   1 
ATOM   4638 O O   . SER C 3 165 ? 134.671 124.514 110.530 1.00 29.04 ? 147 SER C O   1 
ATOM   4639 C CB  . SER C 3 165 ? 133.938 121.446 110.213 1.00 28.21 ? 147 SER C CB  1 
ATOM   4640 O OG  . SER C 3 165 ? 134.075 120.926 108.906 1.00 35.25 ? 147 SER C OG  1 
ATOM   4641 N N   . CYS C 3 166 ? 133.812 124.249 108.447 1.00 21.36 ? 148 CYS C N   1 
ATOM   4642 C CA  . CYS C 3 166 ? 134.640 125.349 107.882 1.00 20.09 ? 148 CYS C CA  1 
ATOM   4643 C C   . CYS C 3 166 ? 133.970 126.010 106.668 1.00 26.07 ? 148 CYS C C   1 
ATOM   4644 O O   . CYS C 3 166 ? 133.407 125.272 105.832 1.00 35.08 ? 148 CYS C O   1 
ATOM   4645 C CB  . CYS C 3 166 ? 136.019 124.843 107.475 1.00 24.02 ? 148 CYS C CB  1 
ATOM   4646 S SG  . CYS C 3 166 ? 137.214 124.847 108.837 1.00 16.39 ? 148 CYS C SG  1 
ATOM   4647 N N   . CYS C 3 167 ? 134.032 127.342 106.583 1.00 23.20 ? 149 CYS C N   1 
ATOM   4648 C CA  . CYS C 3 167 ? 133.502 128.099 105.455 1.00 17.12 ? 149 CYS C CA  1 
ATOM   4649 C C   . CYS C 3 167 ? 134.531 129.145 105.051 1.00 22.16 ? 149 CYS C C   1 
ATOM   4650 O O   . CYS C 3 167 ? 135.167 129.749 105.918 1.00 32.21 ? 149 CYS C O   1 
ATOM   4651 C CB  . CYS C 3 167 ? 132.171 128.775 105.799 1.00 21.49 ? 149 CYS C CB  1 
ATOM   4652 S SG  . CYS C 3 167 ? 132.174 129.705 107.343 1.00 34.30 ? 149 CYS C SG  1 
ATOM   4653 N N   . ARG C 3 168 ? 134.701 129.352 103.743 1.00 20.39 ? 150 ARG C N   1 
ATOM   4654 C CA  . ARG C 3 168 ? 135.666 130.316 103.227 1.00 17.31 ? 150 ARG C CA  1 
ATOM   4655 C C   . ARG C 3 168 ? 135.137 130.940 101.944 1.00 15.56 ? 150 ARG C C   1 
ATOM   4656 O O   . ARG C 3 168 ? 134.543 130.258 101.107 1.00 39.48 ? 150 ARG C O   1 
ATOM   4657 C CB  . ARG C 3 168 ? 137.029 129.656 102.959 1.00 24.48 ? 150 ARG C CB  1 
ATOM   4658 C CG  . ARG C 3 168 ? 137.869 129.348 104.201 1.00 21.16 ? 150 ARG C CG  1 
ATOM   4659 C CD  . ARG C 3 168 ? 138.462 130.596 104.838 1.00 23.40 ? 150 ARG C CD  1 
ATOM   4660 N NE  . ARG C 3 168 ? 139.028 130.332 106.157 1.00 24.46 ? 150 ARG C NE  1 
ATOM   4661 C CZ  . ARG C 3 168 ? 138.351 130.338 107.300 1.00 30.11 ? 150 ARG C CZ  1 
ATOM   4662 N NH1 . ARG C 3 168 ? 137.041 130.531 107.340 1.00 26.40 ? 150 ARG C NH1 1 
ATOM   4663 N NH2 . ARG C 3 168 ? 139.007 130.142 108.439 1.00 37.36 ? 150 ARG C NH2 1 
ATOM   4664 N N   . PHE C 3 169 ? 135.397 132.236 101.777 1.00 16.67 ? 151 PHE C N   1 
ATOM   4665 C CA  . PHE C 3 169 ? 134.856 133.038 100.683 1.00 20.84 ? 151 PHE C CA  1 
ATOM   4666 C C   . PHE C 3 169 ? 135.827 133.047 99.508  1.00 23.07 ? 151 PHE C C   1 
ATOM   4667 O O   . PHE C 3 169 ? 137.007 133.371 99.680  1.00 31.62 ? 151 PHE C O   1 
ATOM   4668 C CB  . PHE C 3 169 ? 134.612 134.483 101.123 1.00 29.83 ? 151 PHE C CB  1 
ATOM   4669 C CG  . PHE C 3 169 ? 133.307 134.721 101.831 1.00 25.44 ? 151 PHE C CG  1 
ATOM   4670 C CD1 . PHE C 3 169 ? 133.208 134.573 103.200 1.00 33.39 ? 151 PHE C CD1 1 
ATOM   4671 C CD2 . PHE C 3 169 ? 132.193 135.145 101.131 1.00 18.15 ? 151 PHE C CD2 1 
ATOM   4672 C CE1 . PHE C 3 169 ? 132.019 134.815 103.849 1.00 23.01 ? 151 PHE C CE1 1 
ATOM   4673 C CE2 . PHE C 3 169 ? 131.004 135.387 101.777 1.00 20.68 ? 151 PHE C CE2 1 
ATOM   4674 C CZ  . PHE C 3 169 ? 130.918 135.223 103.137 1.00 20.35 ? 151 PHE C CZ  1 
ATOM   4675 N N   . LEU C 3 170 ? 135.330 132.701 98.317  1.00 25.59 ? 152 LEU C N   1 
ATOM   4676 C CA  . LEU C 3 170 ? 136.055 133.022 97.087  1.00 28.14 ? 152 LEU C CA  1 
ATOM   4677 C C   . LEU C 3 170 ? 135.895 134.490 96.728  1.00 35.96 ? 152 LEU C C   1 
ATOM   4678 O O   . LEU C 3 170 ? 136.883 135.223 96.616  1.00 41.77 ? 152 LEU C O   1 
ATOM   4679 C CB  . LEU C 3 170 ? 135.556 132.164 95.923  1.00 30.73 ? 152 LEU C CB  1 
ATOM   4680 C CG  . LEU C 3 170 ? 136.301 130.880 95.585  1.00 32.31 ? 152 LEU C CG  1 
ATOM   4681 C CD1 . LEU C 3 170 ? 136.602 130.116 96.834  1.00 33.52 ? 152 LEU C CD1 1 
ATOM   4682 C CD2 . LEU C 3 170 ? 135.486 130.043 94.630  1.00 35.90 ? 152 LEU C CD2 1 
ATOM   4683 N N   . ASP C 3 171 ? 134.654 134.922 96.531  1.00 33.06 ? 153 ASP C N   1 
ATOM   4684 C CA  . ASP C 3 171 ? 134.308 136.297 96.208  1.00 29.53 ? 153 ASP C CA  1 
ATOM   4685 C C   . ASP C 3 171 ? 133.157 136.686 97.118  1.00 32.99 ? 153 ASP C C   1 
ATOM   4686 O O   . ASP C 3 171 ? 132.813 135.965 98.055  1.00 38.10 ? 153 ASP C O   1 
ATOM   4687 C CB  . ASP C 3 171 ? 133.901 136.459 94.739  1.00 33.67 ? 153 ASP C CB  1 
ATOM   4688 C CG  . ASP C 3 171 ? 134.800 135.697 93.787  1.00 41.20 ? 153 ASP C CG  1 
ATOM   4689 O OD1 . ASP C 3 171 ? 136.028 135.675 94.004  1.00 42.81 ? 153 ASP C OD1 1 
ATOM   4690 O OD2 . ASP C 3 171 ? 134.274 135.116 92.815  1.00 35.80 ? 153 ASP C OD2 1 
ATOM   4691 N N   . ASP C 3 172 ? 132.494 137.794 96.780  1.00 35.48 ? 154 ASP C N   1 
ATOM   4692 C CA  . ASP C 3 172 ? 131.276 138.172 97.545  1.00 33.41 ? 154 ASP C CA  1 
ATOM   4693 C C   . ASP C 3 172 ? 130.110 137.307 97.053  1.00 35.66 ? 154 ASP C C   1 
ATOM   4694 O O   . ASP C 3 172 ? 129.079 137.250 97.758  1.00 34.12 ? 154 ASP C O   1 
ATOM   4695 C CB  . ASP C 3 172 ? 130.968 139.655 97.431  1.00 32.35 ? 154 ASP C CB  1 
ATOM   4696 C CG  . ASP C 3 172 ? 131.578 140.531 98.514  1.00 44.45 ? 154 ASP C CG  1 
ATOM   4697 O OD1 . ASP C 3 172 ? 132.284 139.980 99.384  1.00 42.23 ? 154 ASP C OD1 1 
ATOM   4698 O OD2 . ASP C 3 172 ? 131.335 141.755 98.482  1.00 44.71 ? 154 ASP C OD2 1 
ATOM   4699 N N   . ASN C 3 173 ? 130.268 136.657 95.891  1.00 45.95 ? 155 ASN C N   1 
ATOM   4700 C CA  . ASN C 3 173 ? 129.202 135.789 95.395  1.00 40.62 ? 155 ASN C CA  1 
ATOM   4701 C C   . ASN C 3 173 ? 129.420 134.327 95.779  1.00 43.21 ? 155 ASN C C   1 
ATOM   4702 O O   . ASN C 3 173 ? 128.446 133.600 96.005  1.00 46.80 ? 155 ASN C O   1 
ATOM   4703 C CB  . ASN C 3 173 ? 129.092 135.923 93.877  1.00 39.85 ? 155 ASN C CB  1 
ATOM   4704 C CG  . ASN C 3 173 ? 127.736 135.493 93.351  1.00 41.45 ? 155 ASN C CG  1 
ATOM   4705 O OD1 . ASN C 3 173 ? 126.699 135.909 93.865  1.00 43.43 ? 155 ASN C OD1 1 
ATOM   4706 N ND2 . ASN C 3 173 ? 127.738 134.660 92.316  1.00 42.23 ? 155 ASN C ND2 1 
ATOM   4707 N N   . GLN C 3 174 ? 130.675 133.879 95.861  1.00 37.06 ? 156 GLN C N   1 
ATOM   4708 C CA  . GLN C 3 174 ? 131.014 132.462 95.980  1.00 28.78 ? 156 GLN C CA  1 
ATOM   4709 C C   . GLN C 3 174 ? 131.654 132.162 97.328  1.00 28.21 ? 156 GLN C C   1 
ATOM   4710 O O   . GLN C 3 174 ? 132.550 132.886 97.772  1.00 36.50 ? 156 GLN C O   1 
ATOM   4711 C CB  . GLN C 3 174 ? 131.956 132.038 94.855  1.00 29.55 ? 156 GLN C CB  1 
ATOM   4712 C CG  . GLN C 3 174 ? 131.229 131.568 93.613  1.00 31.58 ? 156 GLN C CG  1 
ATOM   4713 C CD  . GLN C 3 174 ? 132.156 131.329 92.445  1.00 40.11 ? 156 GLN C CD  1 
ATOM   4714 O OE1 . GLN C 3 174 ? 133.170 132.008 92.292  1.00 36.64 ? 156 GLN C OE1 1 
ATOM   4715 N NE2 . GLN C 3 174 ? 131.813 130.356 91.612  1.00 40.52 ? 156 GLN C NE2 1 
ATOM   4716 N N   . ILE C 3 175 ? 131.193 131.084 97.965  1.00 27.69 ? 157 ILE C N   1 
ATOM   4717 C CA  . ILE C 3 175 ? 131.693 130.621 99.256  1.00 25.56 ? 157 ILE C CA  1 
ATOM   4718 C C   . ILE C 3 175 ? 131.828 129.105 99.207  1.00 23.09 ? 157 ILE C C   1 
ATOM   4719 O O   . ILE C 3 175 ? 130.944 128.415 98.688  1.00 40.00 ? 157 ILE C O   1 
ATOM   4720 C CB  . ILE C 3 175 ? 130.762 131.063 100.412 1.00 19.92 ? 157 ILE C CB  1 
ATOM   4721 C CG1 . ILE C 3 175 ? 131.385 130.748 101.773 1.00 24.25 ? 157 ILE C CG1 1 
ATOM   4722 C CG2 . ILE C 3 175 ? 129.374 130.435 100.295 1.00 28.27 ? 157 ILE C CG2 1 
ATOM   4723 C CD1 . ILE C 3 175 ? 130.681 131.397 102.935 1.00 22.05 ? 157 ILE C CD1 1 
ATOM   4724 N N   . VAL C 3 176 ? 132.933 128.588 99.745  1.00 15.32 ? 158 VAL C N   1 
ATOM   4725 C CA  . VAL C 3 176 ? 133.168 127.152 99.886  1.00 16.72 ? 158 VAL C CA  1 
ATOM   4726 C C   . VAL C 3 176 ? 132.876 126.780 101.328 1.00 28.99 ? 158 VAL C C   1 
ATOM   4727 O O   . VAL C 3 176 ? 133.145 127.569 102.239 1.00 35.97 ? 158 VAL C O   1 
ATOM   4728 C CB  . VAL C 3 176 ? 134.611 126.753 99.526  1.00 20.44 ? 158 VAL C CB  1 
ATOM   4729 C CG1 . VAL C 3 176 ? 134.691 125.267 99.216  1.00 26.86 ? 158 VAL C CG1 1 
ATOM   4730 C CG2 . VAL C 3 176 ? 135.133 127.572 98.384  1.00 29.59 ? 158 VAL C CG2 1 
ATOM   4731 N N   . THR C 3 177 ? 132.317 125.589 101.532 1.00 23.10 ? 159 THR C N   1 
ATOM   4732 C CA  . THR C 3 177 ? 132.069 125.050 102.860 1.00 21.30 ? 159 THR C CA  1 
ATOM   4733 C C   . THR C 3 177 ? 132.518 123.599 102.921 1.00 25.35 ? 159 THR C C   1 
ATOM   4734 O O   . THR C 3 177 ? 132.517 122.884 101.917 1.00 27.77 ? 159 THR C O   1 
ATOM   4735 C CB  . THR C 3 177 ? 130.584 125.142 103.260 1.00 20.63 ? 159 THR C CB  1 
ATOM   4736 O OG1 . THR C 3 177 ? 129.838 124.116 102.596 1.00 38.80 ? 159 THR C OG1 1 
ATOM   4737 C CG2 . THR C 3 177 ? 130.002 126.509 102.936 1.00 21.42 ? 159 THR C CG2 1 
ATOM   4738 N N   . SER C 3 178 ? 132.920 123.188 104.120 1.00 30.55 ? 160 SER C N   1 
ATOM   4739 C CA  . SER C 3 178 ? 133.226 121.807 104.455 1.00 22.65 ? 160 SER C CA  1 
ATOM   4740 C C   . SER C 3 178 ? 132.314 121.397 105.596 1.00 20.66 ? 160 SER C C   1 
ATOM   4741 O O   . SER C 3 178 ? 131.982 122.220 106.453 1.00 34.84 ? 160 SER C O   1 
ATOM   4742 C CB  . SER C 3 178 ? 134.683 121.637 104.869 1.00 29.38 ? 160 SER C CB  1 
ATOM   4743 O OG  . SER C 3 178 ? 134.844 121.874 106.253 1.00 28.32 ? 160 SER C OG  1 
ATOM   4744 N N   . SER C 3 179 ? 131.909 120.129 105.604 1.00 27.50 ? 161 SER C N   1 
ATOM   4745 C CA  . SER C 3 179 ? 130.858 119.660 106.491 1.00 33.25 ? 161 SER C CA  1 
ATOM   4746 C C   . SER C 3 179 ? 131.167 118.271 107.029 1.00 36.51 ? 161 SER C C   1 
ATOM   4747 O O   . SER C 3 179 ? 132.023 117.549 106.513 1.00 39.97 ? 161 SER C O   1 
ATOM   4748 C CB  . SER C 3 179 ? 129.508 119.642 105.776 1.00 34.53 ? 161 SER C CB  1 
ATOM   4749 O OG  . SER C 3 179 ? 128.485 119.171 106.633 1.00 37.76 ? 161 SER C OG  1 
ATOM   4750 N N   . GLY C 3 180 ? 130.443 117.915 108.089 1.00 35.80 ? 162 GLY C N   1 
ATOM   4751 C CA  . GLY C 3 180 ? 130.538 116.602 108.700 1.00 32.16 ? 162 GLY C CA  1 
ATOM   4752 C C   . GLY C 3 180 ? 129.816 115.503 107.950 1.00 39.60 ? 162 GLY C C   1 
ATOM   4753 O O   . GLY C 3 180 ? 129.854 114.353 108.398 1.00 46.26 ? 162 GLY C O   1 
ATOM   4754 N N   . ASP C 3 181 ? 129.147 115.828 106.836 1.00 41.26 ? 163 ASP C N   1 
ATOM   4755 C CA  . ASP C 3 181 ? 128.593 114.795 105.964 1.00 38.18 ? 163 ASP C CA  1 
ATOM   4756 C C   . ASP C 3 181 ? 129.629 114.264 104.972 1.00 33.19 ? 163 ASP C C   1 
ATOM   4757 O O   . ASP C 3 181 ? 129.263 113.589 104.003 1.00 38.35 ? 163 ASP C O   1 
ATOM   4758 C CB  . ASP C 3 181 ? 127.356 115.339 105.243 1.00 38.21 ? 163 ASP C CB  1 
ATOM   4759 C CG  . ASP C 3 181 ? 127.691 116.114 103.987 1.00 36.91 ? 163 ASP C CG  1 
ATOM   4760 O OD1 . ASP C 3 181 ? 128.564 116.998 104.046 1.00 34.17 ? 163 ASP C OD1 1 
ATOM   4761 O OD2 . ASP C 3 181 ? 127.065 115.851 102.940 1.00 38.35 ? 163 ASP C OD2 1 
ATOM   4762 N N   . THR C 3 182 ? 130.919 114.560 105.188 1.00 33.75 ? 164 THR C N   1 
ATOM   4763 C CA  . THR C 3 182 ? 132.034 114.016 104.415 1.00 34.41 ? 164 THR C CA  1 
ATOM   4764 C C   . THR C 3 182 ? 132.112 114.590 103.003 1.00 41.82 ? 164 THR C C   1 
ATOM   4765 O O   . THR C 3 182 ? 132.810 114.029 102.153 1.00 38.91 ? 164 THR C O   1 
ATOM   4766 C CB  . THR C 3 182 ? 131.979 112.481 104.347 1.00 38.05 ? 164 THR C CB  1 
ATOM   4767 O OG1 . THR C 3 182 ? 130.979 112.063 103.408 1.00 48.24 ? 164 THR C OG1 1 
ATOM   4768 C CG2 . THR C 3 182 ? 131.711 111.865 105.726 1.00 40.29 ? 164 THR C CG2 1 
ATOM   4769 N N   . THR C 3 183 ? 131.409 115.695 102.740 1.00 41.72 ? 165 THR C N   1 
ATOM   4770 C CA  . THR C 3 183 ? 131.432 116.380 101.453 1.00 37.42 ? 165 THR C CA  1 
ATOM   4771 C C   . THR C 3 183 ? 131.728 117.860 101.651 1.00 29.09 ? 165 THR C C   1 
ATOM   4772 O O   . THR C 3 183 ? 131.299 118.461 102.640 1.00 28.81 ? 165 THR C O   1 
ATOM   4773 C CB  . THR C 3 183 ? 130.099 116.218 100.711 1.00 38.84 ? 165 THR C CB  1 
ATOM   4774 O OG1 . THR C 3 183 ? 129.149 117.164 101.217 1.00 35.72 ? 165 THR C OG1 1 
ATOM   4775 C CG2 . THR C 3 183 ? 129.556 114.811 100.872 1.00 35.60 ? 165 THR C CG2 1 
ATOM   4776 N N   . CYS C 3 184 ? 132.475 118.430 100.708 1.00 30.43 ? 166 CYS C N   1 
ATOM   4777 C CA  . CYS C 3 184 ? 132.685 119.867 100.593 1.00 32.35 ? 166 CYS C CA  1 
ATOM   4778 C C   . CYS C 3 184 ? 131.917 120.368 99.378  1.00 36.96 ? 166 CYS C C   1 
ATOM   4779 O O   . CYS C 3 184 ? 131.730 119.623 98.412  1.00 39.82 ? 166 CYS C O   1 
ATOM   4780 C CB  . CYS C 3 184 ? 134.169 120.205 100.444 1.00 26.01 ? 166 CYS C CB  1 
ATOM   4781 S SG  . CYS C 3 184 ? 135.151 119.959 101.915 1.00 43.78 ? 166 CYS C SG  1 
ATOM   4782 N N   . ALA C 3 185 ? 131.470 121.624 99.428  1.00 29.07 ? 167 ALA C N   1 
ATOM   4783 C CA  . ALA C 3 185 ? 130.640 122.203 98.380  1.00 28.58 ? 167 ALA C CA  1 
ATOM   4784 C C   . ALA C 3 185 ? 131.091 123.616 98.045  1.00 24.14 ? 167 ALA C C   1 
ATOM   4785 O O   . ALA C 3 185 ? 131.675 124.313 98.876  1.00 38.11 ? 167 ALA C O   1 
ATOM   4786 C CB  . ALA C 3 185 ? 129.168 122.231 98.796  1.00 33.27 ? 167 ALA C CB  1 
ATOM   4787 N N   . LEU C 3 186 ? 130.816 124.019 96.806  1.00 24.24 ? 168 LEU C N   1 
ATOM   4788 C CA  . LEU C 3 186 ? 130.908 125.403 96.359  1.00 26.09 ? 168 LEU C CA  1 
ATOM   4789 C C   . LEU C 3 186 ? 129.499 125.926 96.130  1.00 28.75 ? 168 LEU C C   1 
ATOM   4790 O O   . LEU C 3 186 ? 128.688 125.257 95.483  1.00 36.81 ? 168 LEU C O   1 
ATOM   4791 C CB  . LEU C 3 186 ? 131.724 125.523 95.069  1.00 27.33 ? 168 LEU C CB  1 
ATOM   4792 C CG  . LEU C 3 186 ? 131.864 126.916 94.436  1.00 32.04 ? 168 LEU C CG  1 
ATOM   4793 C CD1 . LEU C 3 186 ? 132.512 127.924 95.370  1.00 30.60 ? 168 LEU C CD1 1 
ATOM   4794 C CD2 . LEU C 3 186 ? 132.639 126.822 93.142  1.00 35.63 ? 168 LEU C CD2 1 
ATOM   4795 N N   . TRP C 3 187 ? 129.224 127.125 96.638  1.00 22.35 ? 169 TRP C N   1 
ATOM   4796 C CA  . TRP C 3 187 ? 127.904 127.736 96.587  1.00 23.59 ? 169 TRP C CA  1 
ATOM   4797 C C   . TRP C 3 187 ? 127.948 129.011 95.765  1.00 27.74 ? 169 TRP C C   1 
ATOM   4798 O O   . TRP C 3 187 ? 128.948 129.733 95.774  1.00 35.36 ? 169 TRP C O   1 
ATOM   4799 C CB  . TRP C 3 187 ? 127.390 128.082 97.982  1.00 27.46 ? 169 TRP C CB  1 
ATOM   4800 C CG  . TRP C 3 187 ? 127.328 126.946 98.932  1.00 24.89 ? 169 TRP C CG  1 
ATOM   4801 C CD1 . TRP C 3 187 ? 128.364 126.384 99.608  1.00 22.65 ? 169 TRP C CD1 1 
ATOM   4802 C CD2 . TRP C 3 187 ? 126.155 126.237 99.331  1.00 31.55 ? 169 TRP C CD2 1 
ATOM   4803 N NE1 . TRP C 3 187 ? 127.912 125.363 100.404 1.00 34.83 ? 169 TRP C NE1 1 
ATOM   4804 C CE2 . TRP C 3 187 ? 126.556 125.252 100.250 1.00 33.41 ? 169 TRP C CE2 1 
ATOM   4805 C CE3 . TRP C 3 187 ? 124.802 126.338 98.998  1.00 27.47 ? 169 TRP C CE3 1 
ATOM   4806 C CZ2 . TRP C 3 187 ? 125.656 124.374 100.838 1.00 31.63 ? 169 TRP C CZ2 1 
ATOM   4807 C CZ3 . TRP C 3 187 ? 123.912 125.466 99.581  1.00 26.42 ? 169 TRP C CZ3 1 
ATOM   4808 C CH2 . TRP C 3 187 ? 124.340 124.498 100.492 1.00 33.24 ? 169 TRP C CH2 1 
ATOM   4809 N N   . ASP C 3 188 ? 126.811 129.285 95.105  1.00 42.16 ? 170 ASP C N   1 
ATOM   4810 C CA  . ASP C 3 188 ? 126.595 130.591 94.431  1.00 41.97 ? 170 ASP C CA  1 
ATOM   4811 C C   . ASP C 3 188 ? 125.609 131.258 95.388  1.00 39.06 ? 170 ASP C C   1 
ATOM   4812 O O   . ASP C 3 188 ? 124.453 130.786 95.446  1.00 44.78 ? 170 ASP C O   1 
ATOM   4813 C CB  . ASP C 3 188 ? 126.091 130.429 93.008  1.00 48.21 ? 170 ASP C CB  1 
ATOM   4814 C CG  . ASP C 3 188 ? 126.176 131.681 92.148  1.00 50.91 ? 170 ASP C CG  1 
ATOM   4815 O OD1 . ASP C 3 188 ? 127.307 132.162 91.928  1.00 49.07 ? 170 ASP C OD1 1 
ATOM   4816 O OD2 . ASP C 3 188 ? 125.112 132.170 91.715  1.00 49.81 ? 170 ASP C OD2 1 
ATOM   4817 N N   . ILE C 3 189 ? 126.020 132.296 96.112  1.00 35.79 ? 171 ILE C N   1 
ATOM   4818 C CA  . ILE C 3 189 ? 125.227 132.857 97.206  1.00 43.23 ? 171 ILE C CA  1 
ATOM   4819 C C   . ILE C 3 189 ? 123.945 133.488 96.678  1.00 48.30 ? 171 ILE C C   1 
ATOM   4820 O O   . ILE C 3 189 ? 122.881 133.371 97.300  1.00 46.20 ? 171 ILE C O   1 
ATOM   4821 C CB  . ILE C 3 189 ? 126.064 133.866 98.020  1.00 36.81 ? 171 ILE C CB  1 
ATOM   4822 C CG1 . ILE C 3 189 ? 127.224 133.159 98.737  1.00 35.33 ? 171 ILE C CG1 1 
ATOM   4823 C CG2 . ILE C 3 189 ? 125.171 134.622 99.024  1.00 38.44 ? 171 ILE C CG2 1 
ATOM   4824 C CD1 . ILE C 3 189 ? 128.327 134.091 99.220  1.00 33.51 ? 171 ILE C CD1 1 
ATOM   4825 N N   . GLU C 3 190 ? 124.023 134.179 95.538  1.00 50.18 ? 172 GLU C N   1 
ATOM   4826 C CA  . GLU C 3 190 ? 122.836 134.821 94.983  1.00 49.10 ? 172 GLU C CA  1 
ATOM   4827 C C   . GLU C 3 190 ? 121.786 133.784 94.601  1.00 54.67 ? 172 GLU C C   1 
ATOM   4828 O O   . GLU C 3 190 ? 120.596 133.960 94.889  1.00 54.54 ? 172 GLU C O   1 
ATOM   4829 C CB  . GLU C 3 190 ? 123.237 135.687 93.781  1.00 52.52 ? 172 GLU C CB  1 
ATOM   4830 C CG  . GLU C 3 190 ? 122.100 136.233 92.894  1.00 56.96 ? 172 GLU C CG  1 
ATOM   4831 C CD  . GLU C 3 190 ? 121.223 137.245 93.609  1.00 60.44 ? 172 GLU C CD  1 
ATOM   4832 O OE1 . GLU C 3 190 ? 121.511 137.567 94.781  1.00 60.26 ? 172 GLU C OE1 1 
ATOM   4833 O OE2 . GLU C 3 190 ? 120.243 137.719 92.998  1.00 56.40 ? 172 GLU C OE2 1 
ATOM   4834 N N   . THR C 3 191 ? 122.207 132.695 93.956  1.00 55.00 ? 173 THR C N   1 
ATOM   4835 C CA  . THR C 3 191 ? 121.273 131.625 93.621  1.00 52.01 ? 173 THR C CA  1 
ATOM   4836 C C   . THR C 3 191 ? 120.867 130.837 94.860  1.00 51.57 ? 173 THR C C   1 
ATOM   4837 O O   . THR C 3 191 ? 119.714 130.408 94.982  1.00 50.13 ? 173 THR C O   1 
ATOM   4838 C CB  . THR C 3 191 ? 121.895 130.695 92.580  1.00 50.44 ? 173 THR C CB  1 
ATOM   4839 O OG1 . THR C 3 191 ? 122.646 131.466 91.635  1.00 52.79 ? 173 THR C OG1 1 
ATOM   4840 C CG2 . THR C 3 191 ? 120.819 129.911 91.847  1.00 52.83 ? 173 THR C CG2 1 
ATOM   4841 N N   . GLY C 3 192 ? 121.801 130.636 95.789  1.00 50.12 ? 174 GLY C N   1 
ATOM   4842 C CA  . GLY C 3 192 ? 121.544 129.851 96.978  1.00 45.84 ? 174 GLY C CA  1 
ATOM   4843 C C   . GLY C 3 192 ? 121.663 128.356 96.796  1.00 46.69 ? 174 GLY C C   1 
ATOM   4844 O O   . GLY C 3 192 ? 121.138 127.609 97.630  1.00 49.60 ? 174 GLY C O   1 
ATOM   4845 N N   . GLN C 3 193 ? 122.341 127.899 95.742  1.00 40.01 ? 175 GLN C N   1 
ATOM   4846 C CA  . GLN C 3 193 ? 122.452 126.489 95.401  1.00 46.81 ? 175 GLN C CA  1 
ATOM   4847 C C   . GLN C 3 193 ? 123.923 126.132 95.253  1.00 43.53 ? 175 GLN C C   1 
ATOM   4848 O O   . GLN C 3 193 ? 124.772 127.001 95.053  1.00 45.62 ? 175 GLN C O   1 
ATOM   4849 C CB  . GLN C 3 193 ? 121.712 126.172 94.088  1.00 45.04 ? 175 GLN C CB  1 
ATOM   4850 C CG  . GLN C 3 193 ? 120.214 126.532 94.014  1.00 43.46 ? 175 GLN C CG  1 
ATOM   4851 C CD  . GLN C 3 193 ? 119.311 125.919 95.089  1.00 47.00 ? 175 GLN C CD  1 
ATOM   4852 O OE1 . GLN C 3 193 ? 119.749 125.485 96.147  1.00 43.89 ? 175 GLN C OE1 1 
ATOM   4853 N NE2 . GLN C 3 193 ? 118.015 125.900 94.800  1.00 47.64 ? 175 GLN C NE2 1 
ATOM   4854 N N   . GLN C 3 194 ? 124.219 124.838 95.352  1.00 37.68 ? 176 GLN C N   1 
ATOM   4855 C CA  . GLN C 3 194 ? 125.585 124.339 95.225  1.00 28.18 ? 176 GLN C CA  1 
ATOM   4856 C C   . GLN C 3 194 ? 125.934 124.231 93.746  1.00 31.74 ? 176 GLN C C   1 
ATOM   4857 O O   . GLN C 3 194 ? 125.344 123.426 93.020  1.00 42.69 ? 176 GLN C O   1 
ATOM   4858 C CB  . GLN C 3 194 ? 125.741 122.984 95.909  1.00 26.58 ? 176 GLN C CB  1 
ATOM   4859 C CG  . GLN C 3 194 ? 125.631 123.014 97.421  1.00 33.54 ? 176 GLN C CG  1 
ATOM   4860 C CD  . GLN C 3 194 ? 125.962 121.674 98.051  1.00 38.66 ? 176 GLN C CD  1 
ATOM   4861 O OE1 . GLN C 3 194 ? 126.692 120.868 97.475  1.00 41.80 ? 176 GLN C OE1 1 
ATOM   4862 N NE2 . GLN C 3 194 ? 125.426 121.429 99.239  1.00 34.17 ? 176 GLN C NE2 1 
ATOM   4863 N N   . THR C 3 195 ? 126.894 125.042 93.298  1.00 26.43 ? 177 THR C N   1 
ATOM   4864 C CA  . THR C 3 195 ? 127.356 124.935 91.919  1.00 34.30 ? 177 THR C CA  1 
ATOM   4865 C C   . THR C 3 195 ? 128.175 123.668 91.709  1.00 42.29 ? 177 THR C C   1 
ATOM   4866 O O   . THR C 3 195 ? 128.079 123.028 90.656  1.00 43.69 ? 177 THR C O   1 
ATOM   4867 C CB  . THR C 3 195 ? 128.170 126.171 91.540  1.00 32.90 ? 177 THR C CB  1 
ATOM   4868 O OG1 . THR C 3 195 ? 129.121 126.457 92.572  1.00 41.48 ? 177 THR C OG1 1 
ATOM   4869 C CG2 . THR C 3 195 ? 127.258 127.370 91.341  1.00 36.97 ? 177 THR C CG2 1 
ATOM   4870 N N   . THR C 3 196 ? 128.990 123.296 92.697  1.00 42.26 ? 178 THR C N   1 
ATOM   4871 C CA  . THR C 3 196 ? 129.851 122.124 92.624  1.00 34.27 ? 178 THR C CA  1 
ATOM   4872 C C   . THR C 3 196 ? 129.865 121.433 93.979  1.00 29.51 ? 178 THR C C   1 
ATOM   4873 O O   . THR C 3 196 ? 129.755 122.083 95.021  1.00 36.77 ? 178 THR C O   1 
ATOM   4874 C CB  . THR C 3 196 ? 131.282 122.507 92.214  1.00 40.71 ? 178 THR C CB  1 
ATOM   4875 O OG1 . THR C 3 196 ? 131.245 123.268 91.001  1.00 42.77 ? 178 THR C OG1 1 
ATOM   4876 C CG2 . THR C 3 196 ? 132.141 121.272 91.997  1.00 44.61 ? 178 THR C CG2 1 
ATOM   4877 N N   . THR C 3 197 ? 129.998 120.106 93.952  1.00 30.72 ? 179 THR C N   1 
ATOM   4878 C CA  . THR C 3 197 ? 130.101 119.280 95.149  1.00 36.53 ? 179 THR C CA  1 
ATOM   4879 C C   . THR C 3 197 ? 131.359 118.431 95.057  1.00 34.65 ? 179 THR C C   1 
ATOM   4880 O O   . THR C 3 197 ? 131.595 117.773 94.038  1.00 34.55 ? 179 THR C O   1 
ATOM   4881 C CB  . THR C 3 197 ? 128.869 118.384 95.312  1.00 46.57 ? 179 THR C CB  1 
ATOM   4882 O OG1 . THR C 3 197 ? 127.680 119.172 95.173  1.00 43.27 ? 179 THR C OG1 1 
ATOM   4883 C CG2 . THR C 3 197 ? 128.866 117.705 96.677  1.00 38.19 ? 179 THR C CG2 1 
ATOM   4884 N N   . PHE C 3 198 ? 132.158 118.452 96.121  1.00 34.48 ? 180 PHE C N   1 
ATOM   4885 C CA  . PHE C 3 198 ? 133.411 117.711 96.215  1.00 41.73 ? 180 PHE C CA  1 
ATOM   4886 C C   . PHE C 3 198 ? 133.186 116.545 97.168  1.00 45.57 ? 180 PHE C C   1 
ATOM   4887 O O   . PHE C 3 198 ? 132.872 116.760 98.343  1.00 43.19 ? 180 PHE C O   1 
ATOM   4888 C CB  . PHE C 3 198 ? 134.539 118.606 96.731  1.00 34.79 ? 180 PHE C CB  1 
ATOM   4889 C CG  . PHE C 3 198 ? 134.630 119.952 96.050  1.00 33.46 ? 180 PHE C CG  1 
ATOM   4890 C CD1 . PHE C 3 198 ? 133.942 121.041 96.555  1.00 35.21 ? 180 PHE C CD1 1 
ATOM   4891 C CD2 . PHE C 3 198 ? 135.428 120.140 94.939  1.00 30.21 ? 180 PHE C CD2 1 
ATOM   4892 C CE1 . PHE C 3 198 ? 134.021 122.274 95.953  1.00 35.93 ? 180 PHE C CE1 1 
ATOM   4893 C CE2 . PHE C 3 198 ? 135.511 121.382 94.338  1.00 34.44 ? 180 PHE C CE2 1 
ATOM   4894 C CZ  . PHE C 3 198 ? 134.804 122.444 94.847  1.00 37.24 ? 180 PHE C CZ  1 
ATOM   4895 N N   . THR C 3 199 ? 133.340 115.313 96.665  1.00 47.24 ? 181 THR C N   1 
ATOM   4896 C CA  . THR C 3 199 ? 132.981 114.099 97.408  1.00 45.88 ? 181 THR C CA  1 
ATOM   4897 C C   . THR C 3 199 ? 134.052 113.020 97.195  1.00 43.98 ? 181 THR C C   1 
ATOM   4898 O O   . THR C 3 199 ? 133.972 112.192 96.286  1.00 49.24 ? 181 THR C O   1 
ATOM   4899 C CB  . THR C 3 199 ? 131.565 113.614 97.019  1.00 46.16 ? 181 THR C CB  1 
ATOM   4900 O OG1 . THR C 3 199 ? 131.228 112.444 97.775  1.00 50.49 ? 181 THR C OG1 1 
ATOM   4901 C CG2 . THR C 3 199 ? 131.403 113.326 95.509  1.00 39.84 ? 181 THR C CG2 1 
ATOM   4902 N N   . GLY C 3 200 ? 135.082 113.056 98.042  1.00 39.40 ? 182 GLY C N   1 
ATOM   4903 C CA  . GLY C 3 200 ? 136.094 112.013 98.103  1.00 40.84 ? 182 GLY C CA  1 
ATOM   4904 C C   . GLY C 3 200 ? 136.307 111.425 99.484  1.00 35.93 ? 182 GLY C C   1 
ATOM   4905 O O   . GLY C 3 200 ? 136.728 110.273 99.613  1.00 37.07 ? 182 GLY C O   1 
ATOM   4906 N N   . HIS C 3 201 ? 136.017 112.199 100.524 1.00 31.28 ? 183 HIS C N   1 
ATOM   4907 C CA  . HIS C 3 201 ? 136.394 111.806 101.874 1.00 27.56 ? 183 HIS C CA  1 
ATOM   4908 C C   . HIS C 3 201 ? 135.500 110.691 102.399 1.00 37.68 ? 183 HIS C C   1 
ATOM   4909 O O   . HIS C 3 201 ? 134.313 110.617 102.072 1.00 46.89 ? 183 HIS C O   1 
ATOM   4910 C CB  . HIS C 3 201 ? 136.320 113.005 102.813 1.00 36.12 ? 183 HIS C CB  1 
ATOM   4911 C CG  . HIS C 3 201 ? 137.429 113.990 102.620 1.00 38.58 ? 183 HIS C CG  1 
ATOM   4912 N ND1 . HIS C 3 201 ? 138.685 113.808 103.153 1.00 31.14 ? 183 HIS C ND1 1 
ATOM   4913 C CD2 . HIS C 3 201 ? 137.466 115.175 101.968 1.00 40.59 ? 183 HIS C CD2 1 
ATOM   4914 C CE1 . HIS C 3 201 ? 139.451 114.834 102.831 1.00 32.92 ? 183 HIS C CE1 1 
ATOM   4915 N NE2 . HIS C 3 201 ? 138.736 115.676 102.109 1.00 38.10 ? 183 HIS C NE2 1 
ATOM   4916 N N   . THR C 3 202 ? 136.086 109.822 103.221 1.00 43.20 ? 184 THR C N   1 
ATOM   4917 C CA  . THR C 3 202 ? 135.362 108.775 103.935 1.00 42.22 ? 184 THR C CA  1 
ATOM   4918 C C   . THR C 3 202 ? 135.032 109.152 105.376 1.00 41.65 ? 184 THR C C   1 
ATOM   4919 O O   . THR C 3 202 ? 134.523 108.304 106.115 1.00 47.74 ? 184 THR C O   1 
ATOM   4920 C CB  . THR C 3 202 ? 136.171 107.473 103.926 1.00 43.41 ? 184 THR C CB  1 
ATOM   4921 O OG1 . THR C 3 202 ? 137.169 107.517 104.953 1.00 46.10 ? 184 THR C OG1 1 
ATOM   4922 C CG2 . THR C 3 202 ? 136.845 107.261 102.576 1.00 41.27 ? 184 THR C CG2 1 
ATOM   4923 N N   . GLY C 3 203 ? 135.322 110.385 105.795 1.00 38.27 ? 185 GLY C N   1 
ATOM   4924 C CA  . GLY C 3 203 ? 135.031 110.819 107.145 1.00 35.64 ? 185 GLY C CA  1 
ATOM   4925 C C   . GLY C 3 203 ? 134.690 112.295 107.160 1.00 36.89 ? 185 GLY C C   1 
ATOM   4926 O O   . GLY C 3 203 ? 134.709 112.969 106.129 1.00 45.58 ? 185 GLY C O   1 
ATOM   4927 N N   . ASP C 3 204 ? 134.362 112.785 108.353 1.00 27.65 ? 186 ASP C N   1 
ATOM   4928 C CA  . ASP C 3 204 ? 134.000 114.188 108.511 1.00 26.54 ? 186 ASP C CA  1 
ATOM   4929 C C   . ASP C 3 204 ? 135.174 115.084 108.139 1.00 35.82 ? 186 ASP C C   1 
ATOM   4930 O O   . ASP C 3 204 ? 136.323 114.807 108.491 1.00 43.06 ? 186 ASP C O   1 
ATOM   4931 C CB  . ASP C 3 204 ? 133.565 114.474 109.950 1.00 34.43 ? 186 ASP C CB  1 
ATOM   4932 C CG  . ASP C 3 204 ? 132.487 113.527 110.440 1.00 42.08 ? 186 ASP C CG  1 
ATOM   4933 O OD1 . ASP C 3 204 ? 131.924 112.782 109.612 1.00 42.15 ? 186 ASP C OD1 1 
ATOM   4934 O OD2 . ASP C 3 204 ? 132.205 113.527 111.656 1.00 39.51 ? 186 ASP C OD2 1 
ATOM   4935 N N   . VAL C 3 205 ? 134.877 116.167 107.424 1.00 34.37 ? 187 VAL C N   1 
ATOM   4936 C CA  . VAL C 3 205 ? 135.889 117.095 106.933 1.00 29.07 ? 187 VAL C CA  1 
ATOM   4937 C C   . VAL C 3 205 ? 135.974 118.236 107.937 1.00 30.34 ? 187 VAL C C   1 
ATOM   4938 O O   . VAL C 3 205 ? 135.005 118.976 108.134 1.00 39.30 ? 187 VAL C O   1 
ATOM   4939 C CB  . VAL C 3 205 ? 135.565 117.607 105.524 1.00 24.81 ? 187 VAL C CB  1 
ATOM   4940 C CG1 . VAL C 3 205 ? 136.680 118.523 105.032 1.00 25.94 ? 187 VAL C CG1 1 
ATOM   4941 C CG2 . VAL C 3 205 ? 135.356 116.441 104.568 1.00 29.06 ? 187 VAL C CG2 1 
ATOM   4942 N N   . MET C 3 206 ? 137.140 118.376 108.572 1.00 29.32 ? 188 MET C N   1 
ATOM   4943 C CA  . MET C 3 206 ? 137.273 119.291 109.701 1.00 31.74 ? 188 MET C CA  1 
ATOM   4944 C C   . MET C 3 206 ? 137.674 120.693 109.261 1.00 35.04 ? 188 MET C C   1 
ATOM   4945 O O   . MET C 3 206 ? 137.239 121.679 109.866 1.00 37.90 ? 188 MET C O   1 
ATOM   4946 C CB  . MET C 3 206 ? 138.293 118.727 110.695 1.00 36.94 ? 188 MET C CB  1 
ATOM   4947 C CG  . MET C 3 206 ? 137.770 117.612 111.612 1.00 39.32 ? 188 MET C CG  1 
ATOM   4948 S SD  . MET C 3 206 ? 136.296 117.998 112.585 1.00 54.96 ? 188 MET C SD  1 
ATOM   4949 C CE  . MET C 3 206 ? 135.075 117.017 111.727 1.00 31.44 ? 188 MET C CE  1 
ATOM   4950 N N   . SER C 3 207 ? 138.506 120.808 108.226 1.00 27.74 ? 189 SER C N   1 
ATOM   4951 C CA  . SER C 3 207 ? 139.145 122.073 107.891 1.00 20.25 ? 189 SER C CA  1 
ATOM   4952 C C   . SER C 3 207 ? 139.263 122.223 106.384 1.00 27.74 ? 189 SER C C   1 
ATOM   4953 O O   . SER C 3 207 ? 139.120 121.265 105.623 1.00 34.35 ? 189 SER C O   1 
ATOM   4954 C CB  . SER C 3 207 ? 140.526 122.176 108.537 1.00 23.46 ? 189 SER C CB  1 
ATOM   4955 O OG  . SER C 3 207 ? 141.245 120.968 108.373 1.00 21.80 ? 189 SER C OG  1 
ATOM   4956 N N   . LEU C 3 208 ? 139.514 123.462 105.969 1.00 36.33 ? 190 LEU C N   1 
ATOM   4957 C CA  . LEU C 3 208 ? 139.610 123.850 104.572 1.00 28.33 ? 190 LEU C CA  1 
ATOM   4958 C C   . LEU C 3 208 ? 140.557 125.035 104.464 1.00 20.58 ? 190 LEU C C   1 
ATOM   4959 O O   . LEU C 3 208 ? 140.620 125.867 105.374 1.00 24.36 ? 190 LEU C O   1 
ATOM   4960 C CB  . LEU C 3 208 ? 138.218 124.195 104.028 1.00 24.12 ? 190 LEU C CB  1 
ATOM   4961 C CG  . LEU C 3 208 ? 138.058 124.737 102.609 1.00 26.41 ? 190 LEU C CG  1 
ATOM   4962 C CD1 . LEU C 3 208 ? 136.750 124.236 102.035 1.00 32.67 ? 190 LEU C CD1 1 
ATOM   4963 C CD2 . LEU C 3 208 ? 138.088 126.265 102.558 1.00 26.72 ? 190 LEU C CD2 1 
ATOM   4964 N N   . SER C 3 209 ? 141.310 125.103 103.367 1.00 8.05  ? 191 SER C N   1 
ATOM   4965 C CA  . SER C 3 209 ? 142.200 126.226 103.094 1.00 15.72 ? 191 SER C CA  1 
ATOM   4966 C C   . SER C 3 209 ? 142.184 126.546 101.609 1.00 18.36 ? 191 SER C C   1 
ATOM   4967 O O   . SER C 3 209 ? 142.489 125.681 100.783 1.00 29.36 ? 191 SER C O   1 
ATOM   4968 C CB  . SER C 3 209 ? 143.625 125.924 103.548 1.00 26.31 ? 191 SER C CB  1 
ATOM   4969 O OG  . SER C 3 209 ? 144.330 127.126 103.781 1.00 37.10 ? 191 SER C OG  1 
ATOM   4970 N N   . LEU C 3 210 ? 141.853 127.791 101.276 1.00 30.17 ? 192 LEU C N   1 
ATOM   4971 C CA  . LEU C 3 210 ? 141.911 128.242 99.895  1.00 27.67 ? 192 LEU C CA  1 
ATOM   4972 C C   . LEU C 3 210 ? 143.342 128.618 99.526  1.00 21.89 ? 192 LEU C C   1 
ATOM   4973 O O   . LEU C 3 210 ? 144.100 129.142 100.346 1.00 21.90 ? 192 LEU C O   1 
ATOM   4974 C CB  . LEU C 3 210 ? 140.996 129.447 99.689  1.00 31.50 ? 192 LEU C CB  1 
ATOM   4975 C CG  . LEU C 3 210 ? 139.489 129.187 99.652  1.00 30.79 ? 192 LEU C CG  1 
ATOM   4976 C CD1 . LEU C 3 210 ? 138.728 130.488 99.821  1.00 37.01 ? 192 LEU C CD1 1 
ATOM   4977 C CD2 . LEU C 3 210 ? 139.069 128.497 98.378  1.00 21.84 ? 192 LEU C CD2 1 
ATOM   4978 N N   . ALA C 3 211 ? 143.709 128.357 98.276  1.00 12.65 ? 193 ALA C N   1 
ATOM   4979 C CA  . ALA C 3 211 ? 145.037 128.711 97.819  1.00 27.31 ? 193 ALA C CA  1 
ATOM   4980 C C   . ALA C 3 211 ? 145.145 130.225 97.666  1.00 35.01 ? 193 ALA C C   1 
ATOM   4981 O O   . ALA C 3 211 ? 144.128 130.919 97.610  1.00 40.38 ? 193 ALA C O   1 
ATOM   4982 C CB  . ALA C 3 211 ? 145.351 128.033 96.490  1.00 28.13 ? 193 ALA C CB  1 
ATOM   4983 N N   . PRO C 3 212 ? 146.368 130.771 97.626  1.00 32.25 ? 194 PRO C N   1 
ATOM   4984 C CA  . PRO C 3 212 ? 146.495 132.204 97.312  1.00 34.55 ? 194 PRO C CA  1 
ATOM   4985 C C   . PRO C 3 212 ? 145.922 132.573 95.956  1.00 37.51 ? 194 PRO C C   1 
ATOM   4986 O O   . PRO C 3 212 ? 145.236 133.595 95.832  1.00 31.18 ? 194 PRO C O   1 
ATOM   4987 C CB  . PRO C 3 212 ? 148.012 132.423 97.372  1.00 38.64 ? 194 PRO C CB  1 
ATOM   4988 C CG  . PRO C 3 212 ? 148.464 131.411 98.353  1.00 35.28 ? 194 PRO C CG  1 
ATOM   4989 C CD  . PRO C 3 212 ? 147.688 130.200 97.951  1.00 24.82 ? 194 PRO C CD  1 
ATOM   4990 N N   . ASP C 3 213 ? 146.177 131.757 94.932  1.00 41.41 ? 195 ASP C N   1 
ATOM   4991 C CA  . ASP C 3 213 ? 145.611 132.027 93.613  1.00 36.94 ? 195 ASP C CA  1 
ATOM   4992 C C   . ASP C 3 213 ? 144.106 131.771 93.583  1.00 34.64 ? 195 ASP C C   1 
ATOM   4993 O O   . ASP C 3 213 ? 143.419 132.234 92.666  1.00 33.61 ? 195 ASP C O   1 
ATOM   4994 C CB  . ASP C 3 213 ? 146.310 131.184 92.544  1.00 43.54 ? 195 ASP C CB  1 
ATOM   4995 C CG  . ASP C 3 213 ? 146.217 129.694 92.812  1.00 44.57 ? 195 ASP C CG  1 
ATOM   4996 O OD1 . ASP C 3 213 ? 145.199 129.084 92.425  1.00 43.11 ? 195 ASP C OD1 1 
ATOM   4997 O OD2 . ASP C 3 213 ? 147.161 129.133 93.406  1.00 41.81 ? 195 ASP C OD2 1 
ATOM   4998 N N   . THR C 3 214 ? 143.588 130.988 94.538  1.00 41.34 ? 196 THR C N   1 
ATOM   4999 C CA  . THR C 3 214 ? 142.172 130.682 94.808  1.00 36.13 ? 196 THR C CA  1 
ATOM   5000 C C   . THR C 3 214 ? 141.634 129.633 93.819  1.00 32.18 ? 196 THR C C   1 
ATOM   5001 O O   . THR C 3 214 ? 140.576 129.046 94.077  1.00 27.67 ? 196 THR C O   1 
ATOM   5002 C CB  . THR C 3 214 ? 141.296 131.959 94.804  1.00 38.52 ? 196 THR C CB  1 
ATOM   5003 O OG1 . THR C 3 214 ? 141.648 132.764 95.935  1.00 40.63 ? 196 THR C OG1 1 
ATOM   5004 C CG2 . THR C 3 214 ? 139.823 131.669 94.932  1.00 39.24 ? 196 THR C CG2 1 
ATOM   5005 N N   . ARG C 3 215 ? 142.380 129.287 92.765  1.00 40.80 ? 197 ARG C N   1 
ATOM   5006 C CA  . ARG C 3 215 ? 141.872 128.351 91.765  1.00 42.48 ? 197 ARG C CA  1 
ATOM   5007 C C   . ARG C 3 215 ? 141.726 126.932 92.316  1.00 43.89 ? 197 ARG C C   1 
ATOM   5008 O O   . ARG C 3 215 ? 141.035 126.104 91.713  1.00 49.42 ? 197 ARG C O   1 
ATOM   5009 C CB  . ARG C 3 215 ? 142.792 128.351 90.544  1.00 35.96 ? 197 ARG C CB  1 
ATOM   5010 N N   . LEU C 3 216 ? 142.387 126.617 93.434  1.00 31.29 ? 198 LEU C N   1 
ATOM   5011 C CA  . LEU C 3 216 ? 142.330 125.287 94.029  1.00 33.82 ? 198 LEU C CA  1 
ATOM   5012 C C   . LEU C 3 216 ? 142.427 125.397 95.545  1.00 33.66 ? 198 LEU C C   1 
ATOM   5013 O O   . LEU C 3 216 ? 142.913 126.397 96.076  1.00 39.92 ? 198 LEU C O   1 
ATOM   5014 C CB  . LEU C 3 216 ? 143.449 124.371 93.494  1.00 29.37 ? 198 LEU C CB  1 
ATOM   5015 C CG  . LEU C 3 216 ? 144.922 124.639 93.835  1.00 42.66 ? 198 LEU C CG  1 
ATOM   5016 C CD1 . LEU C 3 216 ? 145.792 123.584 93.175  1.00 35.66 ? 198 LEU C CD1 1 
ATOM   5017 C CD2 . LEU C 3 216 ? 145.414 126.024 93.433  1.00 43.80 ? 198 LEU C CD2 1 
ATOM   5018 N N   . PHE C 3 217 ? 141.943 124.364 96.240  1.00 27.80 ? 199 PHE C N   1 
ATOM   5019 C CA  . PHE C 3 217 ? 141.877 124.356 97.696  1.00 18.28 ? 199 PHE C CA  1 
ATOM   5020 C C   . PHE C 3 217 ? 142.081 122.944 98.229  1.00 21.82 ? 199 PHE C C   1 
ATOM   5021 O O   . PHE C 3 217 ? 141.980 121.966 97.487  1.00 40.92 ? 199 PHE C O   1 
ATOM   5022 C CB  . PHE C 3 217 ? 140.541 124.954 98.174  1.00 24.13 ? 199 PHE C CB  1 
ATOM   5023 C CG  . PHE C 3 217 ? 139.388 123.985 98.208  1.00 33.10 ? 199 PHE C CG  1 
ATOM   5024 C CD1 . PHE C 3 217 ? 138.624 123.768 97.077  1.00 35.02 ? 199 PHE C CD1 1 
ATOM   5025 C CD2 . PHE C 3 217 ? 139.020 123.351 99.383  1.00 31.64 ? 199 PHE C CD2 1 
ATOM   5026 C CE1 . PHE C 3 217 ? 137.552 122.904 97.107  1.00 32.68 ? 199 PHE C CE1 1 
ATOM   5027 C CE2 . PHE C 3 217 ? 137.948 122.482 99.412  1.00 22.21 ? 199 PHE C CE2 1 
ATOM   5028 C CZ  . PHE C 3 217 ? 137.214 122.262 98.276  1.00 23.13 ? 199 PHE C CZ  1 
ATOM   5029 N N   . VAL C 3 218 ? 142.384 122.857 99.527  1.00 23.18 ? 200 VAL C N   1 
ATOM   5030 C CA  . VAL C 3 218 ? 142.684 121.603 100.214 1.00 25.33 ? 200 VAL C CA  1 
ATOM   5031 C C   . VAL C 3 218 ? 141.744 121.473 101.403 1.00 32.50 ? 200 VAL C C   1 
ATOM   5032 O O   . VAL C 3 218 ? 141.281 122.484 101.943 1.00 45.99 ? 200 VAL C O   1 
ATOM   5033 C CB  . VAL C 3 218 ? 144.149 121.527 100.690 1.00 19.10 ? 200 VAL C CB  1 
ATOM   5034 C CG1 . VAL C 3 218 ? 145.099 121.464 99.510  1.00 31.50 ? 200 VAL C CG1 1 
ATOM   5035 C CG2 . VAL C 3 218 ? 144.507 122.680 101.641 1.00 20.37 ? 200 VAL C CG2 1 
ATOM   5036 N N   . SER C 3 219 ? 141.461 120.236 101.803 1.00 21.31 ? 201 SER C N   1 
ATOM   5037 C CA  . SER C 3 219 ? 140.642 119.944 102.971 1.00 18.53 ? 201 SER C CA  1 
ATOM   5038 C C   . SER C 3 219 ? 141.264 118.818 103.783 1.00 27.26 ? 201 SER C C   1 
ATOM   5039 O O   . SER C 3 219 ? 141.786 117.852 103.220 1.00 27.25 ? 201 SER C O   1 
ATOM   5040 C CB  . SER C 3 219 ? 139.224 119.561 102.560 1.00 23.97 ? 201 SER C CB  1 
ATOM   5041 O OG  . SER C 3 219 ? 139.237 118.810 101.363 1.00 41.35 ? 201 SER C OG  1 
ATOM   5042 N N   . GLY C 3 220 ? 141.194 118.951 105.104 1.00 29.15 ? 202 GLY C N   1 
ATOM   5043 C CA  . GLY C 3 220 ? 141.627 117.920 106.034 1.00 25.66 ? 202 GLY C CA  1 
ATOM   5044 C C   . GLY C 3 220 ? 140.409 117.311 106.712 1.00 29.23 ? 202 GLY C C   1 
ATOM   5045 O O   . GLY C 3 220 ? 139.426 118.008 106.966 1.00 37.06 ? 202 GLY C O   1 
ATOM   5046 N N   . ALA C 3 221 ? 140.489 116.012 106.997 1.00 23.98 ? 203 ALA C N   1 
ATOM   5047 C CA  . ALA C 3 221 ? 139.321 115.241 107.396 1.00 21.40 ? 203 ALA C CA  1 
ATOM   5048 C C   . ALA C 3 221 ? 139.686 114.160 108.403 1.00 25.47 ? 203 ALA C C   1 
ATOM   5049 O O   . ALA C 3 221 ? 140.858 113.878 108.658 1.00 32.39 ? 203 ALA C O   1 
ATOM   5050 C CB  . ALA C 3 221 ? 138.654 114.614 106.176 1.00 30.29 ? 203 ALA C CB  1 
ATOM   5051 N N   . CYS C 3 222 ? 138.640 113.560 108.978 1.00 31.37 ? 204 CYS C N   1 
ATOM   5052 C CA  . CYS C 3 222 ? 138.800 112.565 110.032 1.00 34.34 ? 204 CYS C CA  1 
ATOM   5053 C C   . CYS C 3 222 ? 139.259 111.208 109.514 1.00 35.17 ? 204 CYS C C   1 
ATOM   5054 O O   . CYS C 3 222 ? 139.635 110.352 110.321 1.00 32.92 ? 204 CYS C O   1 
ATOM   5055 C CB  . CYS C 3 222 ? 137.489 112.406 110.798 1.00 40.38 ? 204 CYS C CB  1 
ATOM   5056 S SG  . CYS C 3 222 ? 137.060 113.833 111.814 1.00 48.93 ? 204 CYS C SG  1 
ATOM   5057 N N   . ASP C 3 223 ? 139.243 110.984 108.194 1.00 35.99 ? 205 ASP C N   1 
ATOM   5058 C CA  . ASP C 3 223 ? 139.840 109.771 107.638 1.00 32.60 ? 205 ASP C CA  1 
ATOM   5059 C C   . ASP C 3 223 ? 141.366 109.837 107.568 1.00 40.38 ? 205 ASP C C   1 
ATOM   5060 O O   . ASP C 3 223 ? 141.970 108.959 106.943 1.00 43.41 ? 205 ASP C O   1 
ATOM   5061 C CB  . ASP C 3 223 ? 139.265 109.476 106.246 1.00 32.37 ? 205 ASP C CB  1 
ATOM   5062 C CG  . ASP C 3 223 ? 139.573 110.557 105.238 1.00 33.97 ? 205 ASP C CG  1 
ATOM   5063 O OD1 . ASP C 3 223 ? 139.123 111.696 105.454 1.00 40.86 ? 205 ASP C OD1 1 
ATOM   5064 O OD2 . ASP C 3 223 ? 140.242 110.266 104.227 1.00 28.73 ? 205 ASP C OD2 1 
ATOM   5065 N N   . ALA C 3 224 ? 141.994 110.869 108.148 1.00 31.75 ? 206 ALA C N   1 
ATOM   5066 C CA  . ALA C 3 224 ? 143.444 110.962 108.280 1.00 25.01 ? 206 ALA C CA  1 
ATOM   5067 C C   . ALA C 3 224 ? 144.112 111.214 106.935 1.00 27.70 ? 206 ALA C C   1 
ATOM   5068 O O   . ALA C 3 224 ? 145.288 110.882 106.761 1.00 38.20 ? 206 ALA C O   1 
ATOM   5069 C CB  . ALA C 3 224 ? 144.017 109.701 108.932 1.00 32.87 ? 206 ALA C CB  1 
ATOM   5070 N N   . SER C 3 225 ? 143.369 111.773 105.977 1.00 27.30 ? 207 SER C N   1 
ATOM   5071 C CA  . SER C 3 225 ? 143.884 112.107 104.660 1.00 33.28 ? 207 SER C CA  1 
ATOM   5072 C C   . SER C 3 225 ? 143.518 113.544 104.325 1.00 29.99 ? 207 SER C C   1 
ATOM   5073 O O   . SER C 3 225 ? 142.494 114.061 104.777 1.00 30.48 ? 207 SER C O   1 
ATOM   5074 C CB  . SER C 3 225 ? 143.328 111.167 103.585 1.00 35.31 ? 207 SER C CB  1 
ATOM   5075 O OG  . SER C 3 225 ? 142.034 111.571 103.173 1.00 34.32 ? 207 SER C OG  1 
ATOM   5076 N N   . ALA C 3 226 ? 144.379 114.183 103.535 1.00 28.55 ? 208 ALA C N   1 
ATOM   5077 C CA  . ALA C 3 226 ? 144.154 115.521 103.007 1.00 19.99 ? 208 ALA C CA  1 
ATOM   5078 C C   . ALA C 3 226 ? 144.109 115.434 101.491 1.00 33.73 ? 208 ALA C C   1 
ATOM   5079 O O   . ALA C 3 226 ? 144.994 114.830 100.880 1.00 40.00 ? 208 ALA C O   1 
ATOM   5080 C CB  . ALA C 3 226 ? 145.254 116.485 103.451 1.00 24.46 ? 208 ALA C CB  1 
ATOM   5081 N N   . LYS C 3 227 ? 143.088 116.046 100.893 1.00 33.06 ? 209 LYS C N   1 
ATOM   5082 C CA  . LYS C 3 227 ? 142.845 115.988 99.459  1.00 27.34 ? 209 LYS C CA  1 
ATOM   5083 C C   . LYS C 3 227 ? 142.967 117.379 98.860  1.00 31.86 ? 209 LYS C C   1 
ATOM   5084 O O   . LYS C 3 227 ? 142.484 118.354 99.441  1.00 42.62 ? 209 LYS C O   1 
ATOM   5085 C CB  . LYS C 3 227 ? 141.458 115.422 99.157  1.00 31.50 ? 209 LYS C CB  1 
ATOM   5086 C CG  . LYS C 3 227 ? 141.234 114.028 99.706  1.00 37.19 ? 209 LYS C CG  1 
ATOM   5087 C CD  . LYS C 3 227 ? 139.947 113.402 99.171  1.00 33.02 ? 209 LYS C CD  1 
ATOM   5088 C CE  . LYS C 3 227 ? 139.884 111.893 99.387  1.00 34.88 ? 209 LYS C CE  1 
ATOM   5089 N NZ  . LYS C 3 227 ? 141.040 111.128 98.835  1.00 39.56 ? 209 LYS C NZ  1 
ATOM   5090 N N   . LEU C 3 228 ? 143.615 117.465 97.701  1.00 32.03 ? 210 LEU C N   1 
ATOM   5091 C CA  . LEU C 3 228 ? 143.710 118.706 96.943  1.00 35.21 ? 210 LEU C CA  1 
ATOM   5092 C C   . LEU C 3 228 ? 142.579 118.728 95.929  1.00 33.11 ? 210 LEU C C   1 
ATOM   5093 O O   . LEU C 3 228 ? 142.441 117.802 95.124  1.00 31.84 ? 210 LEU C O   1 
ATOM   5094 C CB  . LEU C 3 228 ? 145.070 118.831 96.249  1.00 38.77 ? 210 LEU C CB  1 
ATOM   5095 C CG  . LEU C 3 228 ? 145.333 120.038 95.337  1.00 31.03 ? 210 LEU C CG  1 
ATOM   5096 C CD1 . LEU C 3 228 ? 145.616 121.277 96.161  1.00 34.00 ? 210 LEU C CD1 1 
ATOM   5097 C CD2 . LEU C 3 228 ? 146.490 119.748 94.409  1.00 28.41 ? 210 LEU C CD2 1 
ATOM   5098 N N   . TRP C 3 229 ? 141.788 119.795 95.968  1.00 37.55 ? 211 TRP C N   1 
ATOM   5099 C CA  . TRP C 3 229 ? 140.569 119.929 95.188  1.00 29.41 ? 211 TRP C CA  1 
ATOM   5100 C C   . TRP C 3 229 ? 140.749 121.058 94.192  1.00 36.60 ? 211 TRP C C   1 
ATOM   5101 O O   . TRP C 3 229 ? 141.127 122.169 94.572  1.00 52.38 ? 211 TRP C O   1 
ATOM   5102 C CB  . TRP C 3 229 ? 139.382 120.237 96.092  1.00 33.24 ? 211 TRP C CB  1 
ATOM   5103 C CG  . TRP C 3 229 ? 138.961 119.115 96.974  1.00 35.09 ? 211 TRP C CG  1 
ATOM   5104 C CD1 . TRP C 3 229 ? 139.119 119.036 98.322  1.00 26.64 ? 211 TRP C CD1 1 
ATOM   5105 C CD2 . TRP C 3 229 ? 138.284 117.919 96.577  1.00 37.76 ? 211 TRP C CD2 1 
ATOM   5106 N NE1 . TRP C 3 229 ? 138.592 117.861 98.792  1.00 32.10 ? 211 TRP C NE1 1 
ATOM   5107 C CE2 . TRP C 3 229 ? 138.073 117.157 97.739  1.00 33.94 ? 211 TRP C CE2 1 
ATOM   5108 C CE3 . TRP C 3 229 ? 137.842 117.418 95.351  1.00 39.07 ? 211 TRP C CE3 1 
ATOM   5109 C CZ2 . TRP C 3 229 ? 137.439 115.921 97.713  1.00 37.35 ? 211 TRP C CZ2 1 
ATOM   5110 C CZ3 . TRP C 3 229 ? 137.212 116.195 95.327  1.00 49.83 ? 211 TRP C CZ3 1 
ATOM   5111 C CH2 . TRP C 3 229 ? 137.017 115.457 96.500  1.00 49.05 ? 211 TRP C CH2 1 
ATOM   5112 N N   . ASP C 3 230 ? 140.469 120.780 92.925  1.00 42.84 ? 212 ASP C N   1 
ATOM   5113 C CA  . ASP C 3 230 ? 140.446 121.811 91.893  1.00 47.21 ? 212 ASP C CA  1 
ATOM   5114 C C   . ASP C 3 230 ? 139.031 122.370 91.836  1.00 48.44 ? 212 ASP C C   1 
ATOM   5115 O O   . ASP C 3 230 ? 138.080 121.638 91.546  1.00 54.74 ? 212 ASP C O   1 
ATOM   5116 C CB  . ASP C 3 230 ? 140.875 121.249 90.538  1.00 51.68 ? 212 ASP C CB  1 
ATOM   5117 C CG  . ASP C 3 230 ? 141.094 122.324 89.501  1.00 56.80 ? 212 ASP C CG  1 
ATOM   5118 O OD1 . ASP C 3 230 ? 142.041 123.127 89.657  1.00 57.95 ? 212 ASP C OD1 1 
ATOM   5119 O OD2 . ASP C 3 230 ? 140.333 122.360 88.510  1.00 52.75 ? 212 ASP C OD2 1 
ATOM   5120 N N   . VAL C 3 231 ? 138.894 123.666 92.113  1.00 44.24 ? 213 VAL C N   1 
ATOM   5121 C CA  . VAL C 3 231 ? 137.586 124.213 92.459  1.00 43.52 ? 213 VAL C CA  1 
ATOM   5122 C C   . VAL C 3 231 ? 136.659 124.224 91.246  1.00 50.60 ? 213 VAL C C   1 
ATOM   5123 O O   . VAL C 3 231 ? 135.436 124.109 91.385  1.00 51.83 ? 213 VAL C O   1 
ATOM   5124 C CB  . VAL C 3 231 ? 137.741 125.616 93.077  1.00 38.08 ? 213 VAL C CB  1 
ATOM   5125 C CG1 . VAL C 3 231 ? 138.014 126.667 92.006  1.00 46.71 ? 213 VAL C CG1 1 
ATOM   5126 C CG2 . VAL C 3 231 ? 136.515 125.970 93.888  1.00 40.91 ? 213 VAL C CG2 1 
ATOM   5127 N N   . ARG C 3 232 ? 137.218 124.379 90.040  1.00 58.57 ? 214 ARG C N   1 
ATOM   5128 C CA  . ARG C 3 232 ? 136.373 124.499 88.854  1.00 61.41 ? 214 ARG C CA  1 
ATOM   5129 C C   . ARG C 3 232 ? 135.841 123.142 88.389  1.00 58.87 ? 214 ARG C C   1 
ATOM   5130 O O   . ARG C 3 232 ? 134.633 122.979 88.186  1.00 57.59 ? 214 ARG C O   1 
ATOM   5131 C CB  . ARG C 3 232 ? 137.129 125.195 87.721  1.00 57.77 ? 214 ARG C CB  1 
ATOM   5132 C CG  . ARG C 3 232 ? 137.250 126.708 87.875  1.00 58.58 ? 214 ARG C CG  1 
ATOM   5133 C CD  . ARG C 3 232 ? 138.472 127.305 87.160  1.00 60.60 ? 214 ARG C CD  1 
ATOM   5134 N NE  . ARG C 3 232 ? 138.953 128.541 87.768  1.00 60.17 ? 214 ARG C NE  1 
ATOM   5135 C CZ  . ARG C 3 232 ? 140.091 129.151 87.455  1.00 61.33 ? 214 ARG C CZ  1 
ATOM   5136 N NH1 . ARG C 3 232 ? 140.920 128.662 86.543  1.00 61.02 ? 214 ARG C NH1 1 
ATOM   5137 N NH2 . ARG C 3 232 ? 140.399 130.298 88.054  1.00 59.57 ? 214 ARG C NH2 1 
ATOM   5138 N N   . GLU C 3 233 ? 136.722 122.157 88.201  1.00 61.71 ? 215 GLU C N   1 
ATOM   5139 C CA  . GLU C 3 233 ? 136.265 120.855 87.715  1.00 64.59 ? 215 GLU C CA  1 
ATOM   5140 C C   . GLU C 3 233 ? 135.474 120.111 88.780  1.00 67.87 ? 215 GLU C C   1 
ATOM   5141 O O   . GLU C 3 233 ? 134.464 119.465 88.474  1.00 69.20 ? 215 GLU C O   1 
ATOM   5142 C CB  . GLU C 3 233 ? 137.447 119.993 87.254  1.00 65.57 ? 215 GLU C CB  1 
ATOM   5143 C CG  . GLU C 3 233 ? 138.122 120.351 85.912  1.00 69.40 ? 215 GLU C CG  1 
ATOM   5144 C CD  . GLU C 3 233 ? 138.647 121.773 85.794  1.00 71.33 ? 215 GLU C CD  1 
ATOM   5145 O OE1 . GLU C 3 233 ? 138.381 122.604 86.684  1.00 71.45 ? 215 GLU C OE1 1 
ATOM   5146 O OE2 . GLU C 3 233 ? 139.359 122.050 84.803  1.00 67.64 ? 215 GLU C OE2 1 
ATOM   5147 N N   . GLY C 3 234 ? 135.916 120.192 90.032  1.00 62.86 ? 216 GLY C N   1 
ATOM   5148 C CA  . GLY C 3 234 ? 135.281 119.451 91.102  1.00 61.32 ? 216 GLY C CA  1 
ATOM   5149 C C   . GLY C 3 234 ? 135.820 118.060 91.320  1.00 61.94 ? 216 GLY C C   1 
ATOM   5150 O O   . GLY C 3 234 ? 135.044 117.157 91.646  1.00 61.79 ? 216 GLY C O   1 
ATOM   5151 N N   . MET C 3 235 ? 137.126 117.862 91.146  1.00 58.40 ? 217 MET C N   1 
ATOM   5152 C CA  . MET C 3 235 ? 137.785 116.566 91.238  1.00 56.55 ? 217 MET C CA  1 
ATOM   5153 C C   . MET C 3 235 ? 138.933 116.642 92.234  1.00 58.59 ? 217 MET C C   1 
ATOM   5154 O O   . MET C 3 235 ? 139.525 117.706 92.432  1.00 61.53 ? 217 MET C O   1 
ATOM   5155 C CB  . MET C 3 235 ? 138.320 116.116 89.869  1.00 55.51 ? 217 MET C CB  1 
ATOM   5156 C CG  . MET C 3 235 ? 139.177 117.151 89.150  1.00 59.46 ? 217 MET C CG  1 
ATOM   5157 S SD  . MET C 3 235 ? 139.475 116.711 87.434  1.00 75.35 ? 217 MET C SD  1 
ATOM   5158 C CE  . MET C 3 235 ? 140.871 117.768 87.070  1.00 58.17 ? 217 MET C CE  1 
ATOM   5159 N N   . CYS C 3 236 ? 139.238 115.509 92.866  1.00 51.24 ? 218 CYS C N   1 
ATOM   5160 C CA  . CYS C 3 236 ? 140.371 115.402 93.785  1.00 42.23 ? 218 CYS C CA  1 
ATOM   5161 C C   . CYS C 3 236 ? 141.624 115.145 92.962  1.00 47.87 ? 218 CYS C C   1 
ATOM   5162 O O   . CYS C 3 236 ? 141.820 114.049 92.434  1.00 51.83 ? 218 CYS C O   1 
ATOM   5163 C CB  . CYS C 3 236 ? 140.149 114.290 94.803  1.00 36.67 ? 218 CYS C CB  1 
ATOM   5164 S SG  . CYS C 3 236 ? 141.663 113.745 95.614  1.00 45.13 ? 218 CYS C SG  1 
ATOM   5165 N N   . ARG C 3 237 ? 142.479 116.163 92.847  1.00 44.75 ? 219 ARG C N   1 
ATOM   5166 C CA  . ARG C 3 237 ? 143.703 116.007 92.071  1.00 44.72 ? 219 ARG C CA  1 
ATOM   5167 C C   . ARG C 3 237 ? 144.702 115.098 92.779  1.00 47.81 ? 219 ARG C C   1 
ATOM   5168 O O   . ARG C 3 237 ? 145.276 114.197 92.157  1.00 47.27 ? 219 ARG C O   1 
ATOM   5169 C CB  . ARG C 3 237 ? 144.324 117.374 91.802  1.00 43.84 ? 219 ARG C CB  1 
ATOM   5170 C CG  . ARG C 3 237 ? 143.479 118.269 90.897  1.00 45.91 ? 219 ARG C CG  1 
ATOM   5171 C CD  . ARG C 3 237 ? 144.311 119.038 89.879  1.00 48.34 ? 219 ARG C CD  1 
ATOM   5172 N NE  . ARG C 3 237 ? 143.504 119.518 88.761  1.00 52.62 ? 219 ARG C NE  1 
ATOM   5173 C CZ  . ARG C 3 237 ? 143.850 120.497 87.932  1.00 54.23 ? 219 ARG C CZ  1 
ATOM   5174 N NH1 . ARG C 3 237 ? 145.005 121.137 88.047  1.00 50.78 ? 219 ARG C NH1 1 
ATOM   5175 N NH2 . ARG C 3 237 ? 143.017 120.843 86.956  1.00 55.12 ? 219 ARG C NH2 1 
ATOM   5176 N N   . GLN C 3 238 ? 144.924 115.323 94.074  1.00 40.09 ? 220 GLN C N   1 
ATOM   5177 C CA  . GLN C 3 238 ? 145.914 114.595 94.855  1.00 34.68 ? 220 GLN C CA  1 
ATOM   5178 C C   . GLN C 3 238 ? 145.362 114.358 96.250  1.00 32.64 ? 220 GLN C C   1 
ATOM   5179 O O   . GLN C 3 238 ? 144.586 115.165 96.765  1.00 37.54 ? 220 GLN C O   1 
ATOM   5180 C CB  . GLN C 3 238 ? 147.248 115.355 94.959  1.00 34.02 ? 220 GLN C CB  1 
ATOM   5181 C CG  . GLN C 3 238 ? 147.766 115.964 93.657  1.00 41.70 ? 220 GLN C CG  1 
ATOM   5182 C CD  . GLN C 3 238 ? 148.981 116.835 93.869  1.00 39.22 ? 220 GLN C CD  1 
ATOM   5183 O OE1 . GLN C 3 238 ? 149.714 116.671 94.839  1.00 38.25 ? 220 GLN C OE1 1 
ATOM   5184 N NE2 . GLN C 3 238 ? 149.205 117.767 92.954  1.00 44.47 ? 220 GLN C NE2 1 
ATOM   5185 N N   . THR C 3 239 ? 145.765 113.239 96.851  1.00 30.28 ? 221 THR C N   1 
ATOM   5186 C CA  . THR C 3 239 ? 145.399 112.887 98.218  1.00 31.97 ? 221 THR C CA  1 
ATOM   5187 C C   . THR C 3 239 ? 146.658 112.523 98.989  1.00 31.94 ? 221 THR C C   1 
ATOM   5188 O O   . THR C 3 239 ? 147.502 111.773 98.489  1.00 36.22 ? 221 THR C O   1 
ATOM   5189 C CB  . THR C 3 239 ? 144.390 111.733 98.256  1.00 35.37 ? 221 THR C CB  1 
ATOM   5190 O OG1 . THR C 3 239 ? 144.319 111.200 99.584  1.00 23.11 ? 221 THR C OG1 1 
ATOM   5191 C CG2 . THR C 3 239 ? 144.767 110.625 97.277  1.00 41.47 ? 221 THR C CG2 1 
ATOM   5192 N N   . PHE C 3 240 ? 146.773 113.057 100.204 1.00 26.10 ? 222 PHE C N   1 
ATOM   5193 C CA  . PHE C 3 240 ? 147.963 112.940 101.037 1.00 27.84 ? 222 PHE C CA  1 
ATOM   5194 C C   . PHE C 3 240 ? 147.600 112.207 102.318 1.00 31.89 ? 222 PHE C C   1 
ATOM   5195 O O   . PHE C 3 240 ? 146.602 112.543 102.960 1.00 36.71 ? 222 PHE C O   1 
ATOM   5196 C CB  . PHE C 3 240 ? 148.537 114.317 101.378 1.00 29.52 ? 222 PHE C CB  1 
ATOM   5197 C CG  . PHE C 3 240 ? 148.774 115.200 100.185 1.00 29.06 ? 222 PHE C CG  1 
ATOM   5198 C CD1 . PHE C 3 240 ? 147.771 116.020 99.698  1.00 30.00 ? 222 PHE C CD1 1 
ATOM   5199 C CD2 . PHE C 3 240 ? 150.005 115.217 99.560  1.00 26.84 ? 222 PHE C CD2 1 
ATOM   5200 C CE1 . PHE C 3 240 ? 147.993 116.831 98.607  1.00 30.78 ? 222 PHE C CE1 1 
ATOM   5201 C CE2 . PHE C 3 240 ? 150.229 116.025 98.471  1.00 29.58 ? 222 PHE C CE2 1 
ATOM   5202 C CZ  . PHE C 3 240 ? 149.222 116.833 97.994  1.00 36.37 ? 222 PHE C CZ  1 
ATOM   5203 N N   . THR C 3 241 ? 148.412 111.215 102.689 1.00 31.55 ? 223 THR C N   1 
ATOM   5204 C CA  . THR C 3 241 ? 148.184 110.412 103.886 1.00 35.74 ? 223 THR C CA  1 
ATOM   5205 C C   . THR C 3 241 ? 149.498 110.230 104.627 1.00 37.10 ? 223 THR C C   1 
ATOM   5206 O O   . THR C 3 241 ? 150.389 109.524 104.145 1.00 45.68 ? 223 THR C O   1 
ATOM   5207 C CB  . THR C 3 241 ? 147.594 109.046 103.530 1.00 41.26 ? 223 THR C CB  1 
ATOM   5208 O OG1 . THR C 3 241 ? 148.216 108.552 102.338 1.00 38.87 ? 223 THR C OG1 1 
ATOM   5209 C CG2 . THR C 3 241 ? 146.092 109.149 103.316 1.00 36.63 ? 223 THR C CG2 1 
ATOM   5210 N N   . GLY C 3 242 ? 149.616 110.872 105.787 1.00 35.60 ? 224 GLY C N   1 
ATOM   5211 C CA  . GLY C 3 242 ? 150.736 110.654 106.684 1.00 32.45 ? 224 GLY C CA  1 
ATOM   5212 C C   . GLY C 3 242 ? 150.379 110.660 108.159 1.00 33.79 ? 224 GLY C C   1 
ATOM   5213 O O   . GLY C 3 242 ? 151.259 110.462 109.002 1.00 38.98 ? 224 GLY C O   1 
ATOM   5214 N N   . HIS C 3 243 ? 149.105 110.864 108.491 1.00 26.79 ? 225 HIS C N   1 
ATOM   5215 C CA  . HIS C 3 243 ? 148.665 111.107 109.858 1.00 33.32 ? 225 HIS C CA  1 
ATOM   5216 C C   . HIS C 3 243 ? 148.045 109.845 110.438 1.00 36.31 ? 225 HIS C C   1 
ATOM   5217 O O   . HIS C 3 243 ? 147.307 109.136 109.746 1.00 33.58 ? 225 HIS C O   1 
ATOM   5218 C CB  . HIS C 3 243 ? 147.651 112.250 109.904 1.00 31.88 ? 225 HIS C CB  1 
ATOM   5219 C CG  . HIS C 3 243 ? 148.273 113.610 109.885 1.00 33.36 ? 225 HIS C CG  1 
ATOM   5220 N ND1 . HIS C 3 243 ? 148.775 114.210 111.017 1.00 35.83 ? 225 HIS C ND1 1 
ATOM   5221 C CD2 . HIS C 3 243 ? 148.463 114.492 108.877 1.00 35.86 ? 225 HIS C CD2 1 
ATOM   5222 C CE1 . HIS C 3 243 ? 149.255 115.400 110.708 1.00 25.44 ? 225 HIS C CE1 1 
ATOM   5223 N NE2 . HIS C 3 243 ? 149.078 115.596 109.415 1.00 27.02 ? 225 HIS C NE2 1 
ATOM   5224 N N   . GLU C 3 244 ? 148.348 109.568 111.709 1.00 43.72 ? 226 GLU C N   1 
ATOM   5225 C CA  . GLU C 3 244 ? 147.717 108.440 112.387 1.00 44.53 ? 226 GLU C CA  1 
ATOM   5226 C C   . GLU C 3 244 ? 146.248 108.722 112.673 1.00 38.50 ? 226 GLU C C   1 
ATOM   5227 O O   . GLU C 3 244 ? 145.410 107.818 112.578 1.00 42.30 ? 226 GLU C O   1 
ATOM   5228 C CB  . GLU C 3 244 ? 148.447 108.112 113.694 1.00 43.65 ? 226 GLU C CB  1 
ATOM   5229 C CG  . GLU C 3 244 ? 149.986 108.145 113.676 1.00 46.76 ? 226 GLU C CG  1 
ATOM   5230 C CD  . GLU C 3 244 ? 150.644 107.308 112.584 1.00 51.37 ? 226 GLU C CD  1 
ATOM   5231 O OE1 . GLU C 3 244 ? 151.890 107.343 112.500 1.00 52.84 ? 226 GLU C OE1 1 
ATOM   5232 O OE2 . GLU C 3 244 ? 149.951 106.585 111.841 1.00 43.50 ? 226 GLU C OE2 1 
ATOM   5233 N N   . SER C 3 245 ? 145.918 109.968 113.013 1.00 35.80 ? 227 SER C N   1 
ATOM   5234 C CA  . SER C 3 245 ? 144.600 110.350 113.499 1.00 32.18 ? 227 SER C CA  1 
ATOM   5235 C C   . SER C 3 245 ? 144.018 111.456 112.630 1.00 31.31 ? 227 SER C C   1 
ATOM   5236 O O   . SER C 3 245 ? 144.593 111.857 111.615 1.00 32.81 ? 227 SER C O   1 
ATOM   5237 C CB  . SER C 3 245 ? 144.666 110.812 114.959 1.00 39.53 ? 227 SER C CB  1 
ATOM   5238 O OG  . SER C 3 245 ? 143.381 110.800 115.552 1.00 45.37 ? 227 SER C OG  1 
ATOM   5239 N N   . ASP C 3 246 ? 142.844 111.923 113.047 1.00 35.42 ? 228 ASP C N   1 
ATOM   5240 C CA  . ASP C 3 246 ? 142.125 112.979 112.336 1.00 37.83 ? 228 ASP C CA  1 
ATOM   5241 C C   . ASP C 3 246 ? 142.957 114.251 112.201 1.00 30.55 ? 228 ASP C C   1 
ATOM   5242 O O   . ASP C 3 246 ? 143.779 114.572 113.062 1.00 38.11 ? 228 ASP C O   1 
ATOM   5243 C CB  . ASP C 3 246 ? 140.809 113.305 113.050 1.00 40.37 ? 228 ASP C CB  1 
ATOM   5244 C CG  . ASP C 3 246 ? 140.986 113.519 114.533 1.00 42.71 ? 228 ASP C CG  1 
ATOM   5245 O OD1 . ASP C 3 246 ? 142.149 113.537 114.980 1.00 39.88 ? 228 ASP C OD1 1 
ATOM   5246 O OD2 . ASP C 3 246 ? 139.974 113.663 115.248 1.00 43.30 ? 228 ASP C OD2 1 
ATOM   5247 N N   . ILE C 3 247 ? 142.732 114.966 111.099 1.00 27.81 ? 229 ILE C N   1 
ATOM   5248 C CA  . ILE C 3 247 ? 143.421 116.218 110.791 1.00 31.03 ? 229 ILE C CA  1 
ATOM   5249 C C   . ILE C 3 247 ? 142.460 117.353 111.132 1.00 27.39 ? 229 ILE C C   1 
ATOM   5250 O O   . ILE C 3 247 ? 141.497 117.605 110.408 1.00 28.60 ? 229 ILE C O   1 
ATOM   5251 C CB  . ILE C 3 247 ? 143.866 116.263 109.327 1.00 25.04 ? 229 ILE C CB  1 
ATOM   5252 C CG1 . ILE C 3 247 ? 145.057 115.331 109.115 1.00 20.91 ? 229 ILE C CG1 1 
ATOM   5253 C CG2 . ILE C 3 247 ? 144.247 117.675 108.898 1.00 19.01 ? 229 ILE C CG2 1 
ATOM   5254 C CD1 . ILE C 3 247 ? 145.083 114.694 107.759 1.00 28.56 ? 229 ILE C CD1 1 
ATOM   5255 N N   . ASN C 3 248 ? 142.723 118.045 112.243 1.00 31.05 ? 230 ASN C N   1 
ATOM   5256 C CA  . ASN C 3 248 ? 141.821 119.104 112.687 1.00 33.23 ? 230 ASN C CA  1 
ATOM   5257 C C   . ASN C 3 248 ? 141.968 120.369 111.850 1.00 36.17 ? 230 ASN C C   1 
ATOM   5258 O O   . ASN C 3 248 ? 140.970 121.030 111.543 1.00 38.39 ? 230 ASN C O   1 
ATOM   5259 C CB  . ASN C 3 248 ? 142.076 119.434 114.156 1.00 28.67 ? 230 ASN C CB  1 
ATOM   5260 C CG  . ASN C 3 248 ? 141.473 118.422 115.105 1.00 37.52 ? 230 ASN C CG  1 
ATOM   5261 O OD1 . ASN C 3 248 ? 140.535 117.703 114.768 1.00 41.44 ? 230 ASN C OD1 1 
ATOM   5262 N ND2 . ASN C 3 248 ? 142.001 118.380 116.317 1.00 33.05 ? 230 ASN C ND2 1 
ATOM   5263 N N   . ALA C 3 249 ? 143.200 120.726 111.483 1.00 31.62 ? 231 ALA C N   1 
ATOM   5264 C CA  . ALA C 3 249 ? 143.524 122.034 110.924 1.00 12.78 ? 231 ALA C CA  1 
ATOM   5265 C C   . ALA C 3 249 ? 144.405 121.879 109.696 1.00 22.44 ? 231 ALA C C   1 
ATOM   5266 O O   . ALA C 3 249 ? 145.187 120.930 109.606 1.00 32.80 ? 231 ALA C O   1 
ATOM   5267 C CB  . ALA C 3 249 ? 144.230 122.894 111.961 1.00 11.58 ? 231 ALA C CB  1 
ATOM   5268 N N   . ILE C 3 250 ? 144.269 122.812 108.755 1.00 23.43 ? 232 ILE C N   1 
ATOM   5269 C CA  . ILE C 3 250 ? 145.014 122.813 107.501 1.00 20.70 ? 232 ILE C CA  1 
ATOM   5270 C C   . ILE C 3 250 ? 145.286 124.262 107.110 1.00 23.47 ? 232 ILE C C   1 
ATOM   5271 O O   . ILE C 3 250 ? 144.429 125.130 107.313 1.00 28.89 ? 232 ILE C O   1 
ATOM   5272 C CB  . ILE C 3 250 ? 144.242 122.063 106.394 1.00 13.74 ? 232 ILE C CB  1 
ATOM   5273 C CG1 . ILE C 3 250 ? 145.145 121.728 105.198 1.00 19.70 ? 232 ILE C CG1 1 
ATOM   5274 C CG2 . ILE C 3 250 ? 142.972 122.810 105.968 1.00 19.70 ? 232 ILE C CG2 1 
ATOM   5275 C CD1 . ILE C 3 250 ? 144.683 120.510 104.440 1.00 20.41 ? 232 ILE C CD1 1 
ATOM   5276 N N   . CYS C 3 251 ? 146.482 124.529 106.584 1.00 23.93 ? 233 CYS C N   1 
ATOM   5277 C CA  . CYS C 3 251 ? 146.834 125.851 106.079 1.00 12.70 ? 233 CYS C CA  1 
ATOM   5278 C C   . CYS C 3 251 ? 147.781 125.734 104.894 1.00 16.07 ? 233 CYS C C   1 
ATOM   5279 O O   . CYS C 3 251 ? 148.641 124.854 104.854 1.00 25.40 ? 233 CYS C O   1 
ATOM   5280 C CB  . CYS C 3 251 ? 147.494 126.720 107.155 1.00 15.27 ? 233 CYS C CB  1 
ATOM   5281 S SG  . CYS C 3 251 ? 147.416 128.490 106.785 1.00 35.30 ? 233 CYS C SG  1 
ATOM   5282 N N   . PHE C 3 252 ? 147.650 126.671 103.959 1.00 25.11 ? 234 PHE C N   1 
ATOM   5283 C CA  . PHE C 3 252 ? 148.482 126.745 102.766 1.00 18.18 ? 234 PHE C CA  1 
ATOM   5284 C C   . PHE C 3 252 ? 149.766 127.502 103.062 1.00 24.59 ? 234 PHE C C   1 
ATOM   5285 O O   . PHE C 3 252 ? 149.752 128.529 103.746 1.00 28.21 ? 234 PHE C O   1 
ATOM   5286 C CB  . PHE C 3 252 ? 147.757 127.451 101.614 1.00 20.17 ? 234 PHE C CB  1 
ATOM   5287 C CG  . PHE C 3 252 ? 147.220 126.527 100.562 1.00 16.08 ? 234 PHE C CG  1 
ATOM   5288 C CD1 . PHE C 3 252 ? 148.074 125.916 99.664  1.00 15.80 ? 234 PHE C CD1 1 
ATOM   5289 C CD2 . PHE C 3 252 ? 145.867 126.285 100.454 1.00 25.44 ? 234 PHE C CD2 1 
ATOM   5290 C CE1 . PHE C 3 252 ? 147.589 125.076 98.687  1.00 14.32 ? 234 PHE C CE1 1 
ATOM   5291 C CE2 . PHE C 3 252 ? 145.380 125.445 99.478  1.00 27.82 ? 234 PHE C CE2 1 
ATOM   5292 C CZ  . PHE C 3 252 ? 146.243 124.841 98.595  1.00 17.14 ? 234 PHE C CZ  1 
ATOM   5293 N N   . PHE C 3 253 ? 150.873 126.991 102.537 1.00 21.84 ? 235 PHE C N   1 
ATOM   5294 C CA  . PHE C 3 253 ? 152.104 127.754 102.539 1.00 17.92 ? 235 PHE C CA  1 
ATOM   5295 C C   . PHE C 3 253 ? 151.885 129.004 101.681 1.00 29.00 ? 235 PHE C C   1 
ATOM   5296 O O   . PHE C 3 253 ? 151.107 128.957 100.725 1.00 38.62 ? 235 PHE C O   1 
ATOM   5297 C CB  . PHE C 3 253 ? 153.241 126.891 101.995 1.00 19.04 ? 235 PHE C CB  1 
ATOM   5298 C CG  . PHE C 3 253 ? 154.592 127.527 102.078 1.00 25.12 ? 235 PHE C CG  1 
ATOM   5299 C CD1 . PHE C 3 253 ? 155.275 127.577 103.275 1.00 26.92 ? 235 PHE C CD1 1 
ATOM   5300 C CD2 . PHE C 3 253 ? 155.199 128.030 100.951 1.00 25.12 ? 235 PHE C CD2 1 
ATOM   5301 C CE1 . PHE C 3 253 ? 156.522 128.148 103.346 1.00 23.11 ? 235 PHE C CE1 1 
ATOM   5302 C CE2 . PHE C 3 253 ? 156.445 128.604 101.016 1.00 27.47 ? 235 PHE C CE2 1 
ATOM   5303 C CZ  . PHE C 3 253 ? 157.108 128.661 102.214 1.00 27.62 ? 235 PHE C CZ  1 
ATOM   5304 N N   . PRO C 3 254 ? 152.512 130.148 102.017 1.00 23.62 ? 236 PRO C N   1 
ATOM   5305 C CA  . PRO C 3 254 ? 152.186 131.390 101.283 1.00 23.03 ? 236 PRO C CA  1 
ATOM   5306 C C   . PRO C 3 254 ? 152.444 131.337 99.785  1.00 28.83 ? 236 PRO C C   1 
ATOM   5307 O O   . PRO C 3 254 ? 151.766 132.032 99.020  1.00 29.82 ? 236 PRO C O   1 
ATOM   5308 C CB  . PRO C 3 254 ? 153.086 132.417 101.976 1.00 20.12 ? 236 PRO C CB  1 
ATOM   5309 C CG  . PRO C 3 254 ? 153.123 131.935 103.350 1.00 16.82 ? 236 PRO C CG  1 
ATOM   5310 C CD  . PRO C 3 254 ? 153.402 130.477 103.149 1.00 26.09 ? 236 PRO C CD  1 
ATOM   5311 N N   . ASN C 3 255 ? 153.417 130.540 99.346  1.00 30.15 ? 237 ASN C N   1 
ATOM   5312 C CA  . ASN C 3 255 ? 153.644 130.359 97.916  1.00 25.67 ? 237 ASN C CA  1 
ATOM   5313 C C   . ASN C 3 255 ? 152.450 129.691 97.247  1.00 30.45 ? 237 ASN C C   1 
ATOM   5314 O O   . ASN C 3 255 ? 152.099 130.027 96.110  1.00 37.05 ? 237 ASN C O   1 
ATOM   5315 C CB  . ASN C 3 255 ? 154.909 129.532 97.696  1.00 27.13 ? 237 ASN C CB  1 
ATOM   5316 C CG  . ASN C 3 255 ? 155.199 129.285 96.236  1.00 36.43 ? 237 ASN C CG  1 
ATOM   5317 O OD1 . ASN C 3 255 ? 154.759 130.034 95.365  1.00 43.03 ? 237 ASN C OD1 1 
ATOM   5318 N ND2 . ASN C 3 255 ? 155.945 128.222 95.958  1.00 35.69 ? 237 ASN C ND2 1 
ATOM   5319 N N   . GLY C 3 256 ? 151.818 128.741 97.937  1.00 29.30 ? 238 GLY C N   1 
ATOM   5320 C CA  . GLY C 3 256 ? 150.720 127.964 97.399  1.00 17.29 ? 238 GLY C CA  1 
ATOM   5321 C C   . GLY C 3 256 ? 151.096 126.604 96.852  1.00 16.87 ? 238 GLY C C   1 
ATOM   5322 O O   . GLY C 3 256 ? 150.206 125.880 96.390  1.00 34.08 ? 238 GLY C O   1 
ATOM   5323 N N   . ASN C 3 257 ? 152.377 126.231 96.886  1.00 23.60 ? 239 ASN C N   1 
ATOM   5324 C CA  . ASN C 3 257 ? 152.841 124.915 96.461  1.00 28.64 ? 239 ASN C CA  1 
ATOM   5325 C C   . ASN C 3 257 ? 153.040 123.946 97.621  1.00 28.29 ? 239 ASN C C   1 
ATOM   5326 O O   . ASN C 3 257 ? 153.563 122.851 97.403  1.00 37.97 ? 239 ASN C O   1 
ATOM   5327 C CB  . ASN C 3 257 ? 154.159 125.045 95.683  1.00 32.47 ? 239 ASN C CB  1 
ATOM   5328 C CG  . ASN C 3 257 ? 154.044 125.881 94.391  1.00 36.72 ? 239 ASN C CG  1 
ATOM   5329 O OD1 . ASN C 3 257 ? 155.059 126.384 93.914  1.00 39.16 ? 239 ASN C OD1 1 
ATOM   5330 N ND2 . ASN C 3 257 ? 152.847 126.003 93.806  1.00 36.18 ? 239 ASN C ND2 1 
ATOM   5331 N N   . ALA C 3 258 ? 152.657 124.315 98.841  1.00 21.43 ? 240 ALA C N   1 
ATOM   5332 C CA  . ALA C 3 258 ? 152.740 123.419 99.983  1.00 25.85 ? 240 ALA C CA  1 
ATOM   5333 C C   . ALA C 3 258 ? 151.682 123.820 100.999 1.00 28.27 ? 240 ALA C C   1 
ATOM   5334 O O   . ALA C 3 258 ? 151.165 124.938 100.974 1.00 40.72 ? 240 ALA C O   1 
ATOM   5335 C CB  . ALA C 3 258 ? 154.132 123.444 100.623 1.00 25.19 ? 240 ALA C CB  1 
ATOM   5336 N N   . PHE C 3 259 ? 151.354 122.886 101.888 1.00 20.22 ? 241 PHE C N   1 
ATOM   5337 C CA  . PHE C 3 259 ? 150.400 123.130 102.960 1.00 14.83 ? 241 PHE C CA  1 
ATOM   5338 C C   . PHE C 3 259 ? 150.816 122.334 104.188 1.00 17.84 ? 241 PHE C C   1 
ATOM   5339 O O   . PHE C 3 259 ? 151.579 121.371 104.097 1.00 33.18 ? 241 PHE C O   1 
ATOM   5340 C CB  . PHE C 3 259 ? 148.962 122.782 102.531 1.00 26.95 ? 241 PHE C CB  1 
ATOM   5341 C CG  . PHE C 3 259 ? 148.721 121.323 102.303 1.00 24.86 ? 241 PHE C CG  1 
ATOM   5342 C CD1 . PHE C 3 259 ? 149.083 120.727 101.114 1.00 26.06 ? 241 PHE C CD1 1 
ATOM   5343 C CD2 . PHE C 3 259 ? 148.127 120.550 103.279 1.00 21.70 ? 241 PHE C CD2 1 
ATOM   5344 C CE1 . PHE C 3 259 ? 148.855 119.390 100.904 1.00 27.34 ? 241 PHE C CE1 1 
ATOM   5345 C CE2 . PHE C 3 259 ? 147.902 119.214 103.075 1.00 26.27 ? 241 PHE C CE2 1 
ATOM   5346 C CZ  . PHE C 3 259 ? 148.264 118.634 101.887 1.00 31.30 ? 241 PHE C CZ  1 
ATOM   5347 N N   . ALA C 3 260 ? 150.321 122.771 105.346 1.00 13.37 ? 242 ALA C N   1 
ATOM   5348 C CA  . ALA C 3 260 ? 150.614 122.160 106.637 1.00 8.85  ? 242 ALA C CA  1 
ATOM   5349 C C   . ALA C 3 260 ? 149.313 121.763 107.315 1.00 16.35 ? 242 ALA C C   1 
ATOM   5350 O O   . ALA C 3 260 ? 148.365 122.553 107.347 1.00 29.19 ? 242 ALA C O   1 
ATOM   5351 C CB  . ALA C 3 260 ? 151.398 123.118 107.533 1.00 27.17 ? 242 ALA C CB  1 
ATOM   5352 N N   . THR C 3 261 ? 149.278 120.549 107.868 1.00 18.00 ? 243 THR C N   1 
ATOM   5353 C CA  . THR C 3 261 ? 148.092 119.979 108.495 1.00 22.36 ? 243 THR C CA  1 
ATOM   5354 C C   . THR C 3 261 ? 148.335 119.756 109.981 1.00 24.67 ? 243 THR C C   1 
ATOM   5355 O O   . THR C 3 261 ? 149.441 119.393 110.386 1.00 36.51 ? 243 THR C O   1 
ATOM   5356 C CB  . THR C 3 261 ? 147.703 118.652 107.837 1.00 31.42 ? 243 THR C CB  1 
ATOM   5357 O OG1 . THR C 3 261 ? 148.882 117.911 107.510 1.00 36.95 ? 243 THR C OG1 1 
ATOM   5358 C CG2 . THR C 3 261 ? 146.894 118.894 106.581 1.00 30.81 ? 243 THR C CG2 1 
ATOM   5359 N N   . GLY C 3 262 ? 147.297 119.984 110.778 1.00 25.51 ? 244 GLY C N   1 
ATOM   5360 C CA  . GLY C 3 262 ? 147.344 119.762 112.220 1.00 28.09 ? 244 GLY C CA  1 
ATOM   5361 C C   . GLY C 3 262 ? 146.338 118.702 112.619 1.00 29.94 ? 244 GLY C C   1 
ATOM   5362 O O   . GLY C 3 262 ? 145.266 118.602 112.021 1.00 37.70 ? 244 GLY C O   1 
ATOM   5363 N N   . SER C 3 263 ? 146.683 117.924 113.644 1.00 26.32 ? 245 SER C N   1 
ATOM   5364 C CA  . SER C 3 263 ? 146.003 116.673 113.941 1.00 23.91 ? 245 SER C CA  1 
ATOM   5365 C C   . SER C 3 263 ? 145.966 116.415 115.440 1.00 30.93 ? 245 SER C C   1 
ATOM   5366 O O   . SER C 3 263 ? 146.703 117.026 116.216 1.00 41.47 ? 245 SER C O   1 
ATOM   5367 C CB  . SER C 3 263 ? 146.715 115.524 113.244 1.00 34.00 ? 245 SER C CB  1 
ATOM   5368 O OG  . SER C 3 263 ? 148.100 115.635 113.502 1.00 37.67 ? 245 SER C OG  1 
ATOM   5369 N N   . ASP C 3 264 ? 145.091 115.485 115.839 1.00 33.16 ? 246 ASP C N   1 
ATOM   5370 C CA  . ASP C 3 264 ? 145.132 114.929 117.190 1.00 35.43 ? 246 ASP C CA  1 
ATOM   5371 C C   . ASP C 3 264 ? 146.195 113.851 117.357 1.00 42.67 ? 246 ASP C C   1 
ATOM   5372 O O   . ASP C 3 264 ? 146.314 113.286 118.449 1.00 44.68 ? 246 ASP C O   1 
ATOM   5373 C CB  . ASP C 3 264 ? 143.763 114.386 117.599 1.00 37.13 ? 246 ASP C CB  1 
ATOM   5374 C CG  . ASP C 3 264 ? 142.643 115.359 117.307 1.00 47.15 ? 246 ASP C CG  1 
ATOM   5375 O OD1 . ASP C 3 264 ? 142.926 116.572 117.247 1.00 47.69 ? 246 ASP C OD1 1 
ATOM   5376 O OD2 . ASP C 3 264 ? 141.483 114.925 117.155 1.00 46.97 ? 246 ASP C OD2 1 
ATOM   5377 N N   . ASP C 3 265 ? 146.962 113.553 116.306 1.00 42.08 ? 247 ASP C N   1 
ATOM   5378 C CA  . ASP C 3 265 ? 148.201 112.797 116.457 1.00 37.85 ? 247 ASP C CA  1 
ATOM   5379 C C   . ASP C 3 265 ? 149.255 113.577 117.250 1.00 38.34 ? 247 ASP C C   1 
ATOM   5380 O O   . ASP C 3 265 ? 150.250 112.994 117.696 1.00 39.66 ? 247 ASP C O   1 
ATOM   5381 C CB  . ASP C 3 265 ? 148.733 112.439 115.068 1.00 31.22 ? 247 ASP C CB  1 
ATOM   5382 C CG  . ASP C 3 265 ? 149.930 111.519 115.109 1.00 44.65 ? 247 ASP C CG  1 
ATOM   5383 O OD1 . ASP C 3 265 ? 150.123 110.817 116.122 1.00 48.45 ? 247 ASP C OD1 1 
ATOM   5384 O OD2 . ASP C 3 265 ? 150.669 111.485 114.104 1.00 44.66 ? 247 ASP C OD2 1 
ATOM   5385 N N   . ALA C 3 266 ? 149.067 114.900 117.407 1.00 35.18 ? 248 ALA C N   1 
ATOM   5386 C CA  . ALA C 3 266 ? 149.996 115.834 118.047 1.00 32.53 ? 248 ALA C CA  1 
ATOM   5387 C C   . ALA C 3 266 ? 151.188 116.155 117.152 1.00 38.18 ? 248 ALA C C   1 
ATOM   5388 O O   . ALA C 3 266 ? 152.173 116.732 117.624 1.00 43.30 ? 248 ALA C O   1 
ATOM   5389 C CB  . ALA C 3 266 ? 150.486 115.321 119.404 1.00 36.95 ? 248 ALA C CB  1 
ATOM   5390 N N   . THR C 3 267 ? 151.110 115.799 115.868 1.00 31.79 ? 249 THR C N   1 
ATOM   5391 C CA  . THR C 3 267 ? 152.133 116.099 114.879 1.00 25.50 ? 249 THR C CA  1 
ATOM   5392 C C   . THR C 3 267 ? 151.567 117.080 113.867 1.00 27.70 ? 249 THR C C   1 
ATOM   5393 O O   . THR C 3 267 ? 150.386 117.006 113.515 1.00 35.99 ? 249 THR C O   1 
ATOM   5394 C CB  . THR C 3 267 ? 152.598 114.830 114.157 1.00 31.08 ? 249 THR C CB  1 
ATOM   5395 O OG1 . THR C 3 267 ? 151.484 114.214 113.498 1.00 41.75 ? 249 THR C OG1 1 
ATOM   5396 C CG2 . THR C 3 267 ? 153.189 113.840 115.141 1.00 34.58 ? 249 THR C CG2 1 
ATOM   5397 N N   . CYS C 3 268 ? 152.407 118.010 113.425 1.00 36.57 ? 250 CYS C N   1 
ATOM   5398 C CA  . CYS C 3 268 ? 152.131 118.859 112.275 1.00 24.58 ? 250 CYS C CA  1 
ATOM   5399 C C   . CYS C 3 268 ? 153.064 118.438 111.155 1.00 25.22 ? 250 CYS C C   1 
ATOM   5400 O O   . CYS C 3 268 ? 154.266 118.274 111.381 1.00 39.68 ? 250 CYS C O   1 
ATOM   5401 C CB  . CYS C 3 268 ? 152.326 120.340 112.603 1.00 26.55 ? 250 CYS C CB  1 
ATOM   5402 S SG  . CYS C 3 268 ? 151.053 121.056 113.650 1.00 43.16 ? 250 CYS C SG  1 
ATOM   5403 N N   . ARG C 3 269 ? 152.508 118.248 109.963 1.00 21.86 ? 251 ARG C N   1 
ATOM   5404 C CA  . ARG C 3 269 ? 153.243 117.736 108.819 1.00 23.64 ? 251 ARG C CA  1 
ATOM   5405 C C   . ARG C 3 269 ? 153.080 118.694 107.652 1.00 27.05 ? 251 ARG C C   1 
ATOM   5406 O O   . ARG C 3 269 ? 151.972 119.146 107.355 1.00 30.57 ? 251 ARG C O   1 
ATOM   5407 C CB  . ARG C 3 269 ? 152.755 116.335 108.423 1.00 26.97 ? 251 ARG C CB  1 
ATOM   5408 C CG  . ARG C 3 269 ? 152.714 115.338 109.574 1.00 33.57 ? 251 ARG C CG  1 
ATOM   5409 C CD  . ARG C 3 269 ? 152.193 113.985 109.137 1.00 27.15 ? 251 ARG C CD  1 
ATOM   5410 N NE  . ARG C 3 269 ? 153.139 112.914 109.436 1.00 27.93 ? 251 ARG C NE  1 
ATOM   5411 C CZ  . ARG C 3 269 ? 153.209 112.241 110.579 1.00 31.25 ? 251 ARG C CZ  1 
ATOM   5412 N NH1 . ARG C 3 269 ? 152.418 112.515 111.606 1.00 30.28 ? 251 ARG C NH1 1 
ATOM   5413 N NH2 . ARG C 3 269 ? 154.107 111.269 110.702 1.00 38.13 ? 251 ARG C NH2 1 
ATOM   5414 N N   . LEU C 3 270 ? 154.196 118.995 106.995 1.00 28.31 ? 252 LEU C N   1 
ATOM   5415 C CA  . LEU C 3 270 ? 154.224 119.862 105.826 1.00 29.48 ? 252 LEU C CA  1 
ATOM   5416 C C   . LEU C 3 270 ? 154.210 118.983 104.586 1.00 32.10 ? 252 LEU C C   1 
ATOM   5417 O O   . LEU C 3 270 ? 155.040 118.079 104.453 1.00 45.92 ? 252 LEU C O   1 
ATOM   5418 C CB  . LEU C 3 270 ? 155.459 120.770 105.846 1.00 28.54 ? 252 LEU C CB  1 
ATOM   5419 C CG  . LEU C 3 270 ? 155.696 121.753 104.692 1.00 27.56 ? 252 LEU C CG  1 
ATOM   5420 C CD1 . LEU C 3 270 ? 155.051 123.089 104.987 1.00 27.57 ? 252 LEU C CD1 1 
ATOM   5421 C CD2 . LEU C 3 270 ? 157.177 121.940 104.461 1.00 27.07 ? 252 LEU C CD2 1 
ATOM   5422 N N   . PHE C 3 271 ? 153.264 119.253 103.691 1.00 23.41 ? 253 PHE C N   1 
ATOM   5423 C CA  . PHE C 3 271 ? 153.044 118.472 102.483 1.00 20.62 ? 253 PHE C CA  1 
ATOM   5424 C C   . PHE C 3 271 ? 153.319 119.360 101.281 1.00 20.38 ? 253 PHE C C   1 
ATOM   5425 O O   . PHE C 3 271 ? 152.969 120.544 101.296 1.00 33.22 ? 253 PHE C O   1 
ATOM   5426 C CB  . PHE C 3 271 ? 151.610 117.948 102.430 1.00 31.75 ? 253 PHE C CB  1 
ATOM   5427 C CG  . PHE C 3 271 ? 151.340 116.813 103.374 1.00 28.59 ? 253 PHE C CG  1 
ATOM   5428 C CD1 . PHE C 3 271 ? 151.622 115.512 103.012 1.00 33.99 ? 253 PHE C CD1 1 
ATOM   5429 C CD2 . PHE C 3 271 ? 150.783 117.049 104.617 1.00 24.82 ? 253 PHE C CD2 1 
ATOM   5430 C CE1 . PHE C 3 271 ? 151.364 114.471 103.876 1.00 37.93 ? 253 PHE C CE1 1 
ATOM   5431 C CE2 . PHE C 3 271 ? 150.527 116.010 105.481 1.00 25.35 ? 253 PHE C CE2 1 
ATOM   5432 C CZ  . PHE C 3 271 ? 150.819 114.722 105.111 1.00 33.13 ? 253 PHE C CZ  1 
ATOM   5433 N N   . ASP C 3 272 ? 153.946 118.793 100.253 1.00 31.41 ? 254 ASP C N   1 
ATOM   5434 C CA  . ASP C 3 272 ? 154.284 119.515 99.032  1.00 42.51 ? 254 ASP C CA  1 
ATOM   5435 C C   . ASP C 3 272 ? 153.414 119.013 97.886  1.00 42.26 ? 254 ASP C C   1 
ATOM   5436 O O   . ASP C 3 272 ? 153.349 117.806 97.632  1.00 44.08 ? 254 ASP C O   1 
ATOM   5437 C CB  . ASP C 3 272 ? 155.765 119.351 98.707  1.00 44.04 ? 254 ASP C CB  1 
ATOM   5438 C CG  . ASP C 3 272 ? 156.305 120.492 97.876  1.00 47.67 ? 254 ASP C CG  1 
ATOM   5439 O OD1 . ASP C 3 272 ? 155.549 121.045 97.053  1.00 46.40 ? 254 ASP C OD1 1 
ATOM   5440 O OD2 . ASP C 3 272 ? 157.472 120.869 98.081  1.00 48.46 ? 254 ASP C OD2 1 
ATOM   5441 N N   . LEU C 3 273 ? 152.745 119.943 97.202  1.00 34.28 ? 255 LEU C N   1 
ATOM   5442 C CA  . LEU C 3 273 ? 151.816 119.564 96.141  1.00 32.17 ? 255 LEU C CA  1 
ATOM   5443 C C   . LEU C 3 273 ? 152.541 118.916 94.970  1.00 37.14 ? 255 LEU C C   1 
ATOM   5444 O O   . LEU C 3 273 ? 152.136 117.850 94.494  1.00 41.76 ? 255 LEU C O   1 
ATOM   5445 C CB  . LEU C 3 273 ? 151.040 120.790 95.655  1.00 33.52 ? 255 LEU C CB  1 
ATOM   5446 C CG  . LEU C 3 273 ? 149.713 121.135 96.332  1.00 38.65 ? 255 LEU C CG  1 
ATOM   5447 C CD1 . LEU C 3 273 ? 149.767 120.916 97.832  1.00 33.95 ? 255 LEU C CD1 1 
ATOM   5448 C CD2 . LEU C 3 273 ? 149.321 122.565 96.015  1.00 31.83 ? 255 LEU C CD2 1 
ATOM   5449 N N   . ARG C 3 274 ? 153.612 119.547 94.487  1.00 44.42 ? 256 ARG C N   1 
ATOM   5450 C CA  . ARG C 3 274 ? 154.272 119.059 93.281  1.00 52.78 ? 256 ARG C CA  1 
ATOM   5451 C C   . ARG C 3 274 ? 155.026 117.759 93.541  1.00 56.55 ? 256 ARG C C   1 
ATOM   5452 O O   . ARG C 3 274 ? 154.980 116.836 92.721  1.00 54.39 ? 256 ARG C O   1 
ATOM   5453 C CB  . ARG C 3 274 ? 155.206 120.137 92.739  1.00 52.59 ? 256 ARG C CB  1 
ATOM   5454 C CG  . ARG C 3 274 ? 154.459 121.312 92.126  1.00 53.71 ? 256 ARG C CG  1 
ATOM   5455 C CD  . ARG C 3 274 ? 155.392 122.334 91.504  1.00 51.99 ? 256 ARG C CD  1 
ATOM   5456 N NE  . ARG C 3 274 ? 156.339 122.871 92.475  1.00 51.15 ? 256 ARG C NE  1 
ATOM   5457 C CZ  . ARG C 3 274 ? 157.228 123.824 92.228  1.00 51.60 ? 256 ARG C CZ  1 
ATOM   5458 N NH1 . ARG C 3 274 ? 157.325 124.401 91.039  1.00 51.28 ? 256 ARG C NH1 1 
ATOM   5459 N NH2 . ARG C 3 274 ? 158.042 124.216 93.204  1.00 54.29 ? 256 ARG C NH2 1 
ATOM   5460 N N   . ALA C 3 275 ? 155.727 117.666 94.673  1.00 57.05 ? 257 ALA C N   1 
ATOM   5461 C CA  . ALA C 3 275 ? 156.415 116.423 95.009  1.00 52.57 ? 257 ALA C CA  1 
ATOM   5462 C C   . ALA C 3 275 ? 155.431 115.334 95.421  1.00 53.06 ? 257 ALA C C   1 
ATOM   5463 O O   . ALA C 3 275 ? 155.752 114.143 95.330  1.00 62.35 ? 257 ALA C O   1 
ATOM   5464 C CB  . ALA C 3 275 ? 157.433 116.666 96.121  1.00 51.73 ? 257 ALA C CB  1 
ATOM   5465 N N   . ASP C 3 276 ? 154.245 115.718 95.904  1.00 47.39 ? 258 ASP C N   1 
ATOM   5466 C CA  . ASP C 3 276 ? 153.135 114.830 96.264  1.00 49.32 ? 258 ASP C CA  1 
ATOM   5467 C C   . ASP C 3 276 ? 153.360 114.093 97.579  1.00 52.79 ? 258 ASP C C   1 
ATOM   5468 O O   . ASP C 3 276 ? 152.598 113.162 97.873  1.00 56.74 ? 258 ASP C O   1 
ATOM   5469 C CB  . ASP C 3 276 ? 152.852 113.800 95.159  1.00 48.75 ? 258 ASP C CB  1 
ATOM   5470 C CG  . ASP C 3 276 ? 151.403 113.336 95.125  1.00 53.87 ? 258 ASP C CG  1 
ATOM   5471 O OD1 . ASP C 3 276 ? 150.486 114.157 95.318  1.00 54.43 ? 258 ASP C OD1 1 
ATOM   5472 O OD2 . ASP C 3 276 ? 151.181 112.129 94.897  1.00 56.38 ? 258 ASP C OD2 1 
ATOM   5473 N N   . GLN C 3 277 ? 154.353 114.476 98.384  1.00 47.89 ? 259 GLN C N   1 
ATOM   5474 C CA  . GLN C 3 277 ? 154.726 113.740 99.585  1.00 47.92 ? 259 GLN C CA  1 
ATOM   5475 C C   . GLN C 3 277 ? 155.059 114.708 100.713 1.00 47.64 ? 259 GLN C C   1 
ATOM   5476 O O   . GLN C 3 277 ? 155.214 115.913 100.505 1.00 52.57 ? 259 GLN C O   1 
ATOM   5477 C CB  . GLN C 3 277 ? 155.923 112.804 99.331  1.00 48.76 ? 259 GLN C CB  1 
ATOM   5478 C CG  . GLN C 3 277 ? 157.055 113.397 98.507  1.00 47.77 ? 259 GLN C CG  1 
ATOM   5479 C CD  . GLN C 3 277 ? 158.144 112.390 98.231  1.00 53.25 ? 259 GLN C CD  1 
ATOM   5480 O OE1 . GLN C 3 277 ? 158.504 111.599 99.100  1.00 52.16 ? 259 GLN C OE1 1 
ATOM   5481 N NE2 . GLN C 3 277 ? 158.671 112.404 97.012  1.00 58.71 ? 259 GLN C NE2 1 
ATOM   5482 N N   . GLU C 3 278 ? 155.166 114.152 101.917 1.00 41.54 ? 260 GLU C N   1 
ATOM   5483 C CA  . GLU C 3 278 ? 155.451 114.913 103.129 1.00 34.37 ? 260 GLU C CA  1 
ATOM   5484 C C   . GLU C 3 278 ? 156.933 115.265 103.132 1.00 35.90 ? 260 GLU C C   1 
ATOM   5485 O O   . GLU C 3 278 ? 157.788 114.378 103.052 1.00 47.12 ? 260 GLU C O   1 
ATOM   5486 C CB  . GLU C 3 278 ? 155.062 114.091 104.359 1.00 38.29 ? 260 GLU C CB  1 
ATOM   5487 C CG  . GLU C 3 278 ? 155.453 114.627 105.746 1.00 39.92 ? 260 GLU C CG  1 
ATOM   5488 C CD  . GLU C 3 278 ? 155.541 113.518 106.770 1.00 47.12 ? 260 GLU C CD  1 
ATOM   5489 O OE1 . GLU C 3 278 ? 154.520 113.232 107.424 1.00 44.50 ? 260 GLU C OE1 1 
ATOM   5490 O OE2 . GLU C 3 278 ? 156.630 112.927 106.918 1.00 47.30 ? 260 GLU C OE2 1 
ATOM   5491 N N   . LEU C 3 279 ? 157.234 116.560 103.226 1.00 38.47 ? 261 LEU C N   1 
ATOM   5492 C CA  . LEU C 3 279 ? 158.620 116.990 103.374 1.00 37.81 ? 261 LEU C CA  1 
ATOM   5493 C C   . LEU C 3 279 ? 159.099 116.850 104.813 1.00 36.20 ? 261 LEU C C   1 
ATOM   5494 O O   . LEU C 3 279 ? 160.246 116.455 105.051 1.00 37.53 ? 261 LEU C O   1 
ATOM   5495 C CB  . LEU C 3 279 ? 158.772 118.438 102.918 1.00 37.83 ? 261 LEU C CB  1 
ATOM   5496 C CG  . LEU C 3 279 ? 158.412 118.771 101.475 1.00 34.40 ? 261 LEU C CG  1 
ATOM   5497 C CD1 . LEU C 3 279 ? 158.326 120.276 101.322 1.00 41.90 ? 261 LEU C CD1 1 
ATOM   5498 C CD2 . LEU C 3 279 ? 159.429 118.187 100.513 1.00 36.27 ? 261 LEU C CD2 1 
ATOM   5499 N N   . MET C 3 280 ? 158.240 117.168 105.782 1.00 30.05 ? 262 MET C N   1 
ATOM   5500 C CA  . MET C 3 280 ? 158.669 117.384 107.156 1.00 30.74 ? 262 MET C CA  1 
ATOM   5501 C C   . MET C 3 280 ? 157.534 117.089 108.123 1.00 32.97 ? 262 MET C C   1 
ATOM   5502 O O   . MET C 3 280 ? 156.356 117.172 107.766 1.00 39.99 ? 262 MET C O   1 
ATOM   5503 C CB  . MET C 3 280 ? 159.140 118.827 107.336 1.00 31.78 ? 262 MET C CB  1 
ATOM   5504 C CG  . MET C 3 280 ? 159.847 119.119 108.639 1.00 35.15 ? 262 MET C CG  1 
ATOM   5505 S SD  . MET C 3 280 ? 161.113 120.381 108.430 1.00 41.13 ? 262 MET C SD  1 
ATOM   5506 C CE  . MET C 3 280 ? 162.427 119.418 107.702 1.00 38.37 ? 262 MET C CE  1 
ATOM   5507 N N   . THR C 3 281 ? 157.906 116.743 109.356 1.00 32.93 ? 263 THR C N   1 
ATOM   5508 C CA  . THR C 3 281 ? 156.973 116.537 110.457 1.00 33.78 ? 263 THR C CA  1 
ATOM   5509 C C   . THR C 3 281 ? 157.496 117.260 111.690 1.00 28.89 ? 263 THR C C   1 
ATOM   5510 O O   . THR C 3 281 ? 158.692 117.194 111.991 1.00 27.92 ? 263 THR C O   1 
ATOM   5511 C CB  . THR C 3 281 ? 156.767 115.045 110.756 1.00 34.56 ? 263 THR C CB  1 
ATOM   5512 O OG1 . THR C 3 281 ? 155.850 114.899 111.847 1.00 29.37 ? 263 THR C OG1 1 
ATOM   5513 C CG2 . THR C 3 281 ? 158.082 114.339 111.104 1.00 38.79 ? 263 THR C CG2 1 
ATOM   5514 N N   . TYR C 3 282 ? 156.595 117.943 112.397 1.00 23.85 ? 264 TYR C N   1 
ATOM   5515 C CA  . TYR C 3 282 ? 156.926 118.786 113.542 1.00 24.65 ? 264 TYR C CA  1 
ATOM   5516 C C   . TYR C 3 282 ? 156.336 118.149 114.793 1.00 33.05 ? 264 TYR C C   1 
ATOM   5517 O O   . TYR C 3 282 ? 155.118 118.189 114.997 1.00 32.92 ? 264 TYR C O   1 
ATOM   5518 C CB  . TYR C 3 282 ? 156.377 120.195 113.342 1.00 26.56 ? 264 TYR C CB  1 
ATOM   5519 C CG  . TYR C 3 282 ? 156.721 120.803 112.006 1.00 29.64 ? 264 TYR C CG  1 
ATOM   5520 C CD1 . TYR C 3 282 ? 157.990 121.276 111.752 1.00 31.58 ? 264 TYR C CD1 1 
ATOM   5521 C CD2 . TYR C 3 282 ? 155.777 120.898 110.997 1.00 28.68 ? 264 TYR C CD2 1 
ATOM   5522 C CE1 . TYR C 3 282 ? 158.317 121.832 110.538 1.00 27.26 ? 264 TYR C CE1 1 
ATOM   5523 C CE2 . TYR C 3 282 ? 156.096 121.446 109.774 1.00 28.70 ? 264 TYR C CE2 1 
ATOM   5524 C CZ  . TYR C 3 282 ? 157.367 121.912 109.551 1.00 30.19 ? 264 TYR C CZ  1 
ATOM   5525 O OH  . TYR C 3 282 ? 157.693 122.463 108.337 1.00 33.29 ? 264 TYR C OH  1 
ATOM   5526 N N   . SER C 3 283 ? 157.195 117.580 115.637 1.00 45.06 ? 265 SER C N   1 
ATOM   5527 C CA  . SER C 3 283 ? 156.738 116.879 116.827 1.00 39.25 ? 265 SER C CA  1 
ATOM   5528 C C   . SER C 3 283 ? 157.819 116.917 117.895 1.00 46.60 ? 265 SER C C   1 
ATOM   5529 O O   . SER C 3 283 ? 159.009 117.051 117.600 1.00 47.21 ? 265 SER C O   1 
ATOM   5530 C CB  . SER C 3 283 ? 156.376 115.427 116.508 1.00 39.00 ? 265 SER C CB  1 
ATOM   5531 O OG  . SER C 3 283 ? 157.528 114.698 116.126 1.00 44.64 ? 265 SER C OG  1 
ATOM   5532 N N   . HIS C 3 284 ? 157.383 116.794 119.148 1.00 55.47 ? 266 HIS C N   1 
ATOM   5533 C CA  . HIS C 3 284 ? 158.268 116.660 120.294 1.00 54.29 ? 266 HIS C CA  1 
ATOM   5534 C C   . HIS C 3 284 ? 157.667 115.656 121.267 1.00 58.34 ? 266 HIS C C   1 
ATOM   5535 O O   . HIS C 3 284 ? 156.450 115.457 121.304 1.00 56.09 ? 266 HIS C O   1 
ATOM   5536 C CB  . HIS C 3 284 ? 158.494 118.012 121.003 1.00 52.49 ? 266 HIS C CB  1 
ATOM   5537 C CG  . HIS C 3 284 ? 159.846 118.158 121.637 1.00 57.55 ? 266 HIS C CG  1 
ATOM   5538 N ND1 . HIS C 3 284 ? 160.015 118.652 122.912 1.00 57.12 ? 266 HIS C ND1 1 
ATOM   5539 C CD2 . HIS C 3 284 ? 161.092 117.909 121.165 1.00 54.96 ? 266 HIS C CD2 1 
ATOM   5540 C CE1 . HIS C 3 284 ? 161.302 118.683 123.206 1.00 56.01 ? 266 HIS C CE1 1 
ATOM   5541 N NE2 . HIS C 3 284 ? 161.978 118.235 122.163 1.00 53.98 ? 266 HIS C NE2 1 
ATOM   5542 N N   . ASP C 3 285 ? 158.536 115.022 122.058 1.00 68.29 ? 267 ASP C N   1 
ATOM   5543 C CA  . ASP C 3 285 ? 158.076 113.994 122.986 1.00 67.07 ? 267 ASP C CA  1 
ATOM   5544 C C   . ASP C 3 285 ? 157.201 114.585 124.086 1.00 63.61 ? 267 ASP C C   1 
ATOM   5545 O O   . ASP C 3 285 ? 156.291 113.916 124.590 1.00 60.46 ? 267 ASP C O   1 
ATOM   5546 C CB  . ASP C 3 285 ? 159.273 113.261 123.588 1.00 64.68 ? 267 ASP C CB  1 
ATOM   5547 C CG  . ASP C 3 285 ? 159.904 112.285 122.616 1.00 65.40 ? 267 ASP C CG  1 
ATOM   5548 O OD1 . ASP C 3 285 ? 159.793 112.511 121.393 1.00 63.56 ? 267 ASP C OD1 1 
ATOM   5549 O OD2 . ASP C 3 285 ? 160.505 111.291 123.074 1.00 64.89 ? 267 ASP C OD2 1 
ATOM   5550 N N   . ASN C 3 286 ? 157.461 115.835 124.473 1.00 59.78 ? 268 ASN C N   1 
ATOM   5551 C CA  . ASN C 3 286 ? 156.647 116.468 125.510 1.00 61.69 ? 268 ASN C CA  1 
ATOM   5552 C C   . ASN C 3 286 ? 155.215 116.687 125.034 1.00 63.37 ? 268 ASN C C   1 
ATOM   5553 O O   . ASN C 3 286 ? 154.278 116.676 125.840 1.00 63.48 ? 268 ASN C O   1 
ATOM   5554 C CB  . ASN C 3 286 ? 157.257 117.802 125.953 1.00 60.83 ? 268 ASN C CB  1 
ATOM   5555 C CG  . ASN C 3 286 ? 158.761 117.735 126.151 1.00 65.17 ? 268 ASN C CG  1 
ATOM   5556 O OD1 . ASN C 3 286 ? 159.309 116.685 126.483 1.00 63.72 ? 268 ASN C OD1 1 
ATOM   5557 N ND2 . ASN C 3 286 ? 159.435 118.859 125.938 1.00 63.81 ? 268 ASN C ND2 1 
ATOM   5558 N N   . ILE C 3 287 ? 155.027 116.889 123.732 1.00 55.35 ? 269 ILE C N   1 
ATOM   5559 C CA  . ILE C 3 287 ? 153.744 117.309 123.178 1.00 50.08 ? 269 ILE C CA  1 
ATOM   5560 C C   . ILE C 3 287 ? 152.934 116.043 122.912 1.00 52.85 ? 269 ILE C C   1 
ATOM   5561 O O   . ILE C 3 287 ? 153.167 115.335 121.931 1.00 51.51 ? 269 ILE C O   1 
ATOM   5562 C CB  . ILE C 3 287 ? 153.921 118.157 121.912 1.00 47.33 ? 269 ILE C CB  1 
ATOM   5563 C CG1 . ILE C 3 287 ? 154.893 119.333 122.146 1.00 52.97 ? 269 ILE C CG1 1 
ATOM   5564 C CG2 . ILE C 3 287 ? 152.581 118.731 121.419 1.00 45.52 ? 269 ILE C CG2 1 
ATOM   5565 C CD1 . ILE C 3 287 ? 155.241 120.106 120.891 1.00 49.83 ? 269 ILE C CD1 1 
ATOM   5566 N N   . ILE C 3 288 ? 151.971 115.763 123.800 1.00 57.30 ? 270 ILE C N   1 
ATOM   5567 C CA  . ILE C 3 288 ? 150.963 114.725 123.576 1.00 53.01 ? 270 ILE C CA  1 
ATOM   5568 C C   . ILE C 3 288 ? 149.670 115.282 122.995 1.00 54.36 ? 270 ILE C C   1 
ATOM   5569 O O   . ILE C 3 288 ? 148.854 114.508 122.471 1.00 56.23 ? 270 ILE C O   1 
ATOM   5570 C CB  . ILE C 3 288 ? 150.720 113.946 124.894 1.00 54.47 ? 270 ILE C CB  1 
ATOM   5571 C CG1 . ILE C 3 288 ? 149.781 114.665 125.898 1.00 55.40 ? 270 ILE C CG1 1 
ATOM   5572 C CG2 . ILE C 3 288 ? 152.048 113.621 125.568 1.00 56.25 ? 270 ILE C CG2 1 
ATOM   5573 C CD1 . ILE C 3 288 ? 149.378 113.790 127.065 1.00 55.79 ? 270 ILE C CD1 1 
ATOM   5574 N N   . CYS C 3 289 ? 149.453 116.592 123.076 1.00 44.81 ? 271 CYS C N   1 
ATOM   5575 C CA  . CYS C 3 289 ? 148.141 117.160 122.819 1.00 43.73 ? 271 CYS C CA  1 
ATOM   5576 C C   . CYS C 3 289 ? 147.922 117.409 121.330 1.00 47.77 ? 271 CYS C C   1 
ATOM   5577 O O   . CYS C 3 289 ? 148.867 117.577 120.556 1.00 54.33 ? 271 CYS C O   1 
ATOM   5578 C CB  . CYS C 3 289 ? 147.985 118.457 123.603 1.00 46.27 ? 271 CYS C CB  1 
ATOM   5579 S SG  . CYS C 3 289 ? 148.560 118.330 125.311 1.00 64.66 ? 271 CYS C SG  1 
ATOM   5580 N N   . GLY C 3 290 ? 146.652 117.429 120.937 1.00 37.70 ? 272 GLY C N   1 
ATOM   5581 C CA  . GLY C 3 290 ? 146.317 117.612 119.539 1.00 38.10 ? 272 GLY C CA  1 
ATOM   5582 C C   . GLY C 3 290 ? 146.376 119.065 119.114 1.00 35.31 ? 272 GLY C C   1 
ATOM   5583 O O   . GLY C 3 290 ? 146.151 119.980 119.903 1.00 40.29 ? 272 GLY C O   1 
ATOM   5584 N N   . ILE C 3 291 ? 146.652 119.273 117.829 1.00 19.12 ? 273 ILE C N   1 
ATOM   5585 C CA  . ILE C 3 291 ? 146.774 120.612 117.264 1.00 23.50 ? 273 ILE C CA  1 
ATOM   5586 C C   . ILE C 3 291 ? 145.385 121.090 116.866 1.00 27.09 ? 273 ILE C C   1 
ATOM   5587 O O   . ILE C 3 291 ? 144.733 120.490 116.006 1.00 33.88 ? 273 ILE C O   1 
ATOM   5588 C CB  . ILE C 3 291 ? 147.736 120.630 116.065 1.00 25.51 ? 273 ILE C CB  1 
ATOM   5589 C CG1 . ILE C 3 291 ? 149.135 120.189 116.510 1.00 27.56 ? 273 ILE C CG1 1 
ATOM   5590 C CG2 . ILE C 3 291 ? 147.765 122.017 115.403 1.00 16.87 ? 273 ILE C CG2 1 
ATOM   5591 C CD1 . ILE C 3 291 ? 149.573 118.878 115.920 1.00 32.23 ? 273 ILE C CD1 1 
ATOM   5592 N N   . THR C 3 292 ? 144.932 122.173 117.499 1.00 28.37 ? 274 THR C N   1 
ATOM   5593 C CA  . THR C 3 292 ? 143.604 122.706 117.213 1.00 31.62 ? 274 THR C CA  1 
ATOM   5594 C C   . THR C 3 292 ? 143.604 123.567 115.954 1.00 31.84 ? 274 THR C C   1 
ATOM   5595 O O   . THR C 3 292 ? 142.614 123.588 115.213 1.00 28.75 ? 274 THR C O   1 
ATOM   5596 C CB  . THR C 3 292 ? 143.104 123.515 118.407 1.00 26.87 ? 274 THR C CB  1 
ATOM   5597 O OG1 . THR C 3 292 ? 143.873 124.715 118.528 1.00 30.03 ? 274 THR C OG1 1 
ATOM   5598 C CG2 . THR C 3 292 ? 143.245 122.716 119.683 1.00 25.57 ? 274 THR C CG2 1 
ATOM   5599 N N   . SER C 3 293 ? 144.692 124.296 115.706 1.00 28.45 ? 275 SER C N   1 
ATOM   5600 C CA  . SER C 3 293 ? 144.784 125.225 114.589 1.00 16.32 ? 275 SER C CA  1 
ATOM   5601 C C   . SER C 3 293 ? 146.229 125.311 114.122 1.00 15.81 ? 275 SER C C   1 
ATOM   5602 O O   . SER C 3 293 ? 147.152 124.979 114.867 1.00 28.87 ? 275 SER C O   1 
ATOM   5603 C CB  . SER C 3 293 ? 144.280 126.614 114.981 1.00 28.34 ? 275 SER C CB  1 
ATOM   5604 O OG  . SER C 3 293 ? 144.580 126.890 116.337 1.00 29.47 ? 275 SER C OG  1 
ATOM   5605 N N   . VAL C 3 294 ? 146.416 125.743 112.873 1.00 10.29 ? 276 VAL C N   1 
ATOM   5606 C CA  . VAL C 3 294 ? 147.736 126.034 112.327 1.00 22.04 ? 276 VAL C CA  1 
ATOM   5607 C C   . VAL C 3 294 ? 147.643 127.277 111.455 1.00 28.87 ? 276 VAL C C   1 
ATOM   5608 O O   . VAL C 3 294 ? 146.580 127.607 110.921 1.00 26.14 ? 276 VAL C O   1 
ATOM   5609 C CB  . VAL C 3 294 ? 148.333 124.856 111.515 1.00 18.59 ? 276 VAL C CB  1 
ATOM   5610 C CG1 . VAL C 3 294 ? 148.734 123.725 112.435 1.00 21.78 ? 276 VAL C CG1 1 
ATOM   5611 C CG2 . VAL C 3 294 ? 147.368 124.359 110.445 1.00 24.73 ? 276 VAL C CG2 1 
ATOM   5612 N N   . SER C 3 295 ? 148.771 127.971 111.316 1.00 20.79 ? 277 SER C N   1 
ATOM   5613 C CA  . SER C 3 295 ? 148.880 129.069 110.370 1.00 15.23 ? 277 SER C CA  1 
ATOM   5614 C C   . SER C 3 295 ? 150.346 129.291 110.048 1.00 13.17 ? 277 SER C C   1 
ATOM   5615 O O   . SER C 3 295 ? 151.232 128.879 110.798 1.00 21.60 ? 277 SER C O   1 
ATOM   5616 C CB  . SER C 3 295 ? 148.273 130.362 110.911 1.00 27.52 ? 277 SER C CB  1 
ATOM   5617 O OG  . SER C 3 295 ? 146.861 130.272 110.982 1.00 35.04 ? 277 SER C OG  1 
ATOM   5618 N N   . PHE C 3 296 ? 150.586 129.973 108.932 1.00 26.19 ? 278 PHE C N   1 
ATOM   5619 C CA  . PHE C 3 296 ? 151.924 130.302 108.465 1.00 20.65 ? 278 PHE C CA  1 
ATOM   5620 C C   . PHE C 3 296 ? 152.161 131.795 108.609 1.00 27.61 ? 278 PHE C C   1 
ATOM   5621 O O   . PHE C 3 296 ? 151.256 132.608 108.414 1.00 33.73 ? 278 PHE C O   1 
ATOM   5622 C CB  . PHE C 3 296 ? 152.134 129.908 106.998 1.00 16.64 ? 278 PHE C CB  1 
ATOM   5623 C CG  . PHE C 3 296 ? 152.606 128.500 106.805 1.00 25.95 ? 278 PHE C CG  1 
ATOM   5624 C CD1 . PHE C 3 296 ? 153.945 128.186 106.928 1.00 26.34 ? 278 PHE C CD1 1 
ATOM   5625 C CD2 . PHE C 3 296 ? 151.716 127.492 106.484 1.00 21.79 ? 278 PHE C CD2 1 
ATOM   5626 C CE1 . PHE C 3 296 ? 154.384 126.895 106.742 1.00 24.50 ? 278 PHE C CE1 1 
ATOM   5627 C CE2 . PHE C 3 296 ? 152.153 126.202 106.299 1.00 15.30 ? 278 PHE C CE2 1 
ATOM   5628 C CZ  . PHE C 3 296 ? 153.487 125.904 106.427 1.00 14.90 ? 278 PHE C CZ  1 
ATOM   5629 N N   . SER C 3 297 ? 153.394 132.143 108.957 1.00 28.42 ? 279 SER C N   1 
ATOM   5630 C CA  . SER C 3 297 ? 153.819 133.529 108.913 1.00 19.09 ? 279 SER C CA  1 
ATOM   5631 C C   . SER C 3 297 ? 153.896 133.995 107.461 1.00 30.70 ? 279 SER C C   1 
ATOM   5632 O O   . SER C 3 297 ? 153.786 133.200 106.525 1.00 40.40 ? 279 SER C O   1 
ATOM   5633 C CB  . SER C 3 297 ? 155.166 133.687 109.608 1.00 22.90 ? 279 SER C CB  1 
ATOM   5634 O OG  . SER C 3 297 ? 155.814 134.866 109.193 1.00 27.95 ? 279 SER C OG  1 
ATOM   5635 N N   . LYS C 3 298 ? 154.070 135.308 107.277 1.00 34.35 ? 280 LYS C N   1 
ATOM   5636 C CA  . LYS C 3 298 ? 154.005 135.883 105.934 1.00 28.22 ? 280 LYS C CA  1 
ATOM   5637 C C   . LYS C 3 298 ? 155.103 135.334 105.031 1.00 34.02 ? 280 LYS C C   1 
ATOM   5638 O O   . LYS C 3 298 ? 154.853 135.016 103.864 1.00 34.52 ? 280 LYS C O   1 
ATOM   5639 C CB  . LYS C 3 298 ? 154.101 137.404 106.002 1.00 37.06 ? 280 LYS C CB  1 
ATOM   5640 C CG  . LYS C 3 298 ? 153.987 138.062 104.637 1.00 40.68 ? 280 LYS C CG  1 
ATOM   5641 C CD  . LYS C 3 298 ? 153.309 139.414 104.716 1.00 38.55 ? 280 LYS C CD  1 
ATOM   5642 C CE  . LYS C 3 298 ? 153.207 140.071 103.350 1.00 32.66 ? 280 LYS C CE  1 
ATOM   5643 N NZ  . LYS C 3 298 ? 154.280 141.071 103.115 1.00 32.99 ? 280 LYS C NZ  1 
ATOM   5644 N N   . SER C 3 299 ? 156.327 135.223 105.548 1.00 35.03 ? 281 SER C N   1 
ATOM   5645 C CA  . SER C 3 299 ? 157.402 134.628 104.762 1.00 30.14 ? 281 SER C CA  1 
ATOM   5646 C C   . SER C 3 299 ? 157.197 133.129 104.591 1.00 32.71 ? 281 SER C C   1 
ATOM   5647 O O   . SER C 3 299 ? 157.617 132.552 103.582 1.00 34.33 ? 281 SER C O   1 
ATOM   5648 C CB  . SER C 3 299 ? 158.750 134.900 105.423 1.00 33.91 ? 281 SER C CB  1 
ATOM   5649 O OG  . SER C 3 299 ? 158.635 134.900 106.833 1.00 42.86 ? 281 SER C OG  1 
ATOM   5650 N N   . GLY C 3 300 ? 156.554 132.484 105.565 1.00 30.67 ? 282 GLY C N   1 
ATOM   5651 C CA  . GLY C 3 300 ? 156.451 131.042 105.617 1.00 26.29 ? 282 GLY C CA  1 
ATOM   5652 C C   . GLY C 3 300 ? 157.551 130.358 106.398 1.00 30.36 ? 282 GLY C C   1 
ATOM   5653 O O   . GLY C 3 300 ? 157.532 129.127 106.510 1.00 40.88 ? 282 GLY C O   1 
ATOM   5654 N N   . ARG C 3 301 ? 158.513 131.111 106.937 1.00 39.24 ? 283 ARG C N   1 
ATOM   5655 C CA  . ARG C 3 301 ? 159.557 130.511 107.760 1.00 33.37 ? 283 ARG C CA  1 
ATOM   5656 C C   . ARG C 3 301 ? 158.995 129.980 109.069 1.00 27.42 ? 283 ARG C C   1 
ATOM   5657 O O   . ARG C 3 301 ? 159.484 128.975 109.596 1.00 37.86 ? 283 ARG C O   1 
ATOM   5658 C CB  . ARG C 3 301 ? 160.657 131.541 108.030 1.00 26.59 ? 283 ARG C CB  1 
ATOM   5659 C CG  . ARG C 3 301 ? 161.947 130.998 108.644 1.00 27.94 ? 283 ARG C CG  1 
ATOM   5660 C CD  . ARG C 3 301 ? 162.779 130.165 107.687 1.00 38.88 ? 283 ARG C CD  1 
ATOM   5661 N NE  . ARG C 3 301 ? 163.733 129.326 108.407 1.00 33.72 ? 283 ARG C NE  1 
ATOM   5662 C CZ  . ARG C 3 301 ? 164.980 129.661 108.721 1.00 38.61 ? 283 ARG C CZ  1 
ATOM   5663 N NH1 . ARG C 3 301 ? 165.486 130.849 108.424 1.00 36.28 ? 283 ARG C NH1 1 
ATOM   5664 N NH2 . ARG C 3 301 ? 165.742 128.779 109.359 1.00 42.12 ? 283 ARG C NH2 1 
ATOM   5665 N N   . LEU C 3 302 ? 157.976 130.640 109.609 1.00 22.84 ? 284 LEU C N   1 
ATOM   5666 C CA  . LEU C 3 302 ? 157.401 130.307 110.905 1.00 21.80 ? 284 LEU C CA  1 
ATOM   5667 C C   . LEU C 3 302 ? 156.075 129.592 110.705 1.00 23.08 ? 284 LEU C C   1 
ATOM   5668 O O   . LEU C 3 302 ? 155.195 130.098 110.003 1.00 38.54 ? 284 LEU C O   1 
ATOM   5669 C CB  . LEU C 3 302 ? 157.191 131.569 111.741 1.00 27.59 ? 284 LEU C CB  1 
ATOM   5670 C CG  . LEU C 3 302 ? 158.197 131.814 112.865 1.00 28.00 ? 284 LEU C CG  1 
ATOM   5671 C CD1 . LEU C 3 302 ? 159.603 131.996 112.324 1.00 33.71 ? 284 LEU C CD1 1 
ATOM   5672 C CD2 . LEU C 3 302 ? 157.777 133.019 113.680 1.00 28.74 ? 284 LEU C CD2 1 
ATOM   5673 N N   . LEU C 3 303 ? 155.943 128.418 111.316 1.00 25.36 ? 285 LEU C N   1 
ATOM   5674 C CA  . LEU C 3 303 ? 154.684 127.690 111.399 1.00 28.76 ? 285 LEU C CA  1 
ATOM   5675 C C   . LEU C 3 303 ? 154.167 127.790 112.825 1.00 26.07 ? 285 LEU C C   1 
ATOM   5676 O O   . LEU C 3 303 ? 154.795 127.276 113.755 1.00 34.68 ? 285 LEU C O   1 
ATOM   5677 C CB  . LEU C 3 303 ? 154.864 126.223 110.995 1.00 24.52 ? 285 LEU C CB  1 
ATOM   5678 C CG  . LEU C 3 303 ? 153.637 125.304 111.036 1.00 21.75 ? 285 LEU C CG  1 
ATOM   5679 C CD1 . LEU C 3 303 ? 152.516 125.802 110.148 1.00 21.52 ? 285 LEU C CD1 1 
ATOM   5680 C CD2 . LEU C 3 303 ? 154.031 123.900 110.644 1.00 27.43 ? 285 LEU C CD2 1 
ATOM   5681 N N   . LEU C 3 304 ? 153.024 128.446 112.985 1.00 19.82 ? 286 LEU C N   1 
ATOM   5682 C CA  . LEU C 3 304 ? 152.388 128.651 114.278 1.00 26.56 ? 286 LEU C CA  1 
ATOM   5683 C C   . LEU C 3 304 ? 151.231 127.674 114.407 1.00 29.61 ? 286 LEU C C   1 
ATOM   5684 O O   . LEU C 3 304 ? 150.381 127.600 113.515 1.00 36.67 ? 286 LEU C O   1 
ATOM   5685 C CB  . LEU C 3 304 ? 151.892 130.091 114.414 1.00 22.21 ? 286 LEU C CB  1 
ATOM   5686 C CG  . LEU C 3 304 ? 152.970 131.171 114.304 1.00 26.41 ? 286 LEU C CG  1 
ATOM   5687 C CD1 . LEU C 3 304 ? 152.999 131.766 112.912 1.00 32.49 ? 286 LEU C CD1 1 
ATOM   5688 C CD2 . LEU C 3 304 ? 152.736 132.262 115.323 1.00 30.31 ? 286 LEU C CD2 1 
ATOM   5689 N N   . ALA C 3 305 ? 151.209 126.926 115.508 1.00 19.05 ? 287 ALA C N   1 
ATOM   5690 C CA  . ALA C 3 305 ? 150.212 125.895 115.751 1.00 12.52 ? 287 ALA C CA  1 
ATOM   5691 C C   . ALA C 3 305 ? 149.623 126.069 117.140 1.00 16.97 ? 287 ALA C C   1 
ATOM   5692 O O   . ALA C 3 305 ? 150.328 126.418 118.088 1.00 31.35 ? 287 ALA C O   1 
ATOM   5693 C CB  . ALA C 3 305 ? 150.816 124.495 115.619 1.00 29.36 ? 287 ALA C CB  1 
ATOM   5694 N N   . GLY C 3 306 ? 148.323 125.811 117.245 1.00 24.93 ? 288 GLY C N   1 
ATOM   5695 C CA  . GLY C 3 306 ? 147.596 125.908 118.496 1.00 27.12 ? 288 GLY C CA  1 
ATOM   5696 C C   . GLY C 3 306 ? 147.204 124.538 119.003 1.00 30.35 ? 288 GLY C C   1 
ATOM   5697 O O   . GLY C 3 306 ? 146.772 123.696 118.213 1.00 36.42 ? 288 GLY C O   1 
ATOM   5698 N N   . TYR C 3 307 ? 147.333 124.312 120.312 1.00 32.70 ? 289 TYR C N   1 
ATOM   5699 C CA  . TYR C 3 307 ? 147.254 122.984 120.904 1.00 26.48 ? 289 TYR C CA  1 
ATOM   5700 C C   . TYR C 3 307 ? 146.181 122.950 121.983 1.00 30.33 ? 289 TYR C C   1 
ATOM   5701 O O   . TYR C 3 307 ? 145.723 123.986 122.467 1.00 33.50 ? 289 TYR C O   1 
ATOM   5702 C CB  . TYR C 3 307 ? 148.597 122.563 121.516 1.00 26.88 ? 289 TYR C CB  1 
ATOM   5703 C CG  . TYR C 3 307 ? 149.720 122.400 120.519 1.00 22.41 ? 289 TYR C CG  1 
ATOM   5704 C CD1 . TYR C 3 307 ? 150.358 123.502 119.972 1.00 25.83 ? 289 TYR C CD1 1 
ATOM   5705 C CD2 . TYR C 3 307 ? 150.142 121.144 120.125 1.00 28.92 ? 289 TYR C CD2 1 
ATOM   5706 C CE1 . TYR C 3 307 ? 151.382 123.355 119.064 1.00 29.03 ? 289 TYR C CE1 1 
ATOM   5707 C CE2 . TYR C 3 307 ? 151.165 120.991 119.218 1.00 30.81 ? 289 TYR C CE2 1 
ATOM   5708 C CZ  . TYR C 3 307 ? 151.781 122.096 118.691 1.00 32.70 ? 289 TYR C CZ  1 
ATOM   5709 O OH  . TYR C 3 307 ? 152.802 121.936 117.785 1.00 38.42 ? 289 TYR C OH  1 
ATOM   5710 N N   . ASP C 3 308 ? 145.782 121.730 122.353 1.00 36.18 ? 290 ASP C N   1 
ATOM   5711 C CA  . ASP C 3 308 ? 144.906 121.534 123.503 1.00 38.77 ? 290 ASP C CA  1 
ATOM   5712 C C   . ASP C 3 308 ? 145.635 121.691 124.833 1.00 41.22 ? 290 ASP C C   1 
ATOM   5713 O O   . ASP C 3 308 ? 144.981 121.674 125.881 1.00 40.97 ? 290 ASP C O   1 
ATOM   5714 C CB  . ASP C 3 308 ? 144.244 120.155 123.443 1.00 41.01 ? 290 ASP C CB  1 
ATOM   5715 C CG  . ASP C 3 308 ? 143.368 119.980 122.224 1.00 45.24 ? 290 ASP C CG  1 
ATOM   5716 O OD1 . ASP C 3 308 ? 142.236 120.499 122.227 1.00 45.32 ? 290 ASP C OD1 1 
ATOM   5717 O OD2 . ASP C 3 308 ? 143.810 119.316 121.263 1.00 45.36 ? 290 ASP C OD2 1 
ATOM   5718 N N   . ASP C 3 309 ? 146.966 121.847 124.820 1.00 44.55 ? 291 ASP C N   1 
ATOM   5719 C CA  . ASP C 3 309 ? 147.725 122.114 126.039 1.00 36.03 ? 291 ASP C CA  1 
ATOM   5720 C C   . ASP C 3 309 ? 147.638 123.566 126.503 1.00 39.91 ? 291 ASP C C   1 
ATOM   5721 O O   . ASP C 3 309 ? 148.453 123.971 127.337 1.00 48.29 ? 291 ASP C O   1 
ATOM   5722 C CB  . ASP C 3 309 ? 149.195 121.750 125.828 1.00 32.20 ? 291 ASP C CB  1 
ATOM   5723 N N   . PHE C 3 310 ? 146.727 124.369 125.938 1.00 34.76 ? 292 PHE C N   1 
ATOM   5724 C CA  . PHE C 3 310 ? 146.452 125.745 126.351 1.00 36.01 ? 292 PHE C CA  1 
ATOM   5725 C C   . PHE C 3 310 ? 147.543 126.702 125.873 1.00 39.75 ? 292 PHE C C   1 
ATOM   5726 O O   . PHE C 3 310 ? 147.565 127.863 126.293 1.00 47.60 ? 292 PHE C O   1 
ATOM   5727 C CB  . PHE C 3 310 ? 146.282 125.906 127.881 1.00 38.83 ? 292 PHE C CB  1 
ATOM   5728 C CG  . PHE C 3 310 ? 145.229 125.005 128.537 1.00 37.53 ? 292 PHE C CG  1 
ATOM   5729 C CD1 . PHE C 3 310 ? 144.324 124.234 127.812 1.00 40.24 ? 292 PHE C CD1 1 
ATOM   5730 C CD2 . PHE C 3 310 ? 145.142 124.973 129.919 1.00 34.08 ? 292 PHE C CD2 1 
ATOM   5731 C CE1 . PHE C 3 310 ? 143.386 123.447 128.450 1.00 38.48 ? 292 PHE C CE1 1 
ATOM   5732 C CE2 . PHE C 3 310 ? 144.203 124.189 130.557 1.00 38.20 ? 292 PHE C CE2 1 
ATOM   5733 C CZ  . PHE C 3 310 ? 143.325 123.427 129.821 1.00 39.36 ? 292 PHE C CZ  1 
ATOM   5734 N N   . ASN C 3 311 ? 148.448 126.239 125.003 1.00 34.10 ? 293 ASN C N   1 
ATOM   5735 C CA  . ASN C 3 311 ? 149.568 127.033 124.518 1.00 36.77 ? 293 ASN C CA  1 
ATOM   5736 C C   . ASN C 3 311 ? 149.739 126.810 123.024 1.00 35.58 ? 293 ASN C C   1 
ATOM   5737 O O   . ASN C 3 311 ? 149.266 125.812 122.474 1.00 35.25 ? 293 ASN C O   1 
ATOM   5738 C CB  . ASN C 3 311 ? 150.863 126.673 125.256 1.00 35.79 ? 293 ASN C CB  1 
ATOM   5739 C CG  . ASN C 3 311 ? 151.420 125.329 124.831 1.00 47.92 ? 293 ASN C CG  1 
ATOM   5740 O OD1 . ASN C 3 311 ? 152.583 125.224 124.445 1.00 41.04 ? 293 ASN C OD1 1 
ATOM   5741 N ND2 . ASN C 3 311 ? 150.593 124.294 124.900 1.00 48.77 ? 293 ASN C ND2 1 
ATOM   5742 N N   . CYS C 3 312 ? 150.412 127.760 122.374 1.00 30.61 ? 294 CYS C N   1 
ATOM   5743 C CA  . CYS C 3 312 ? 150.733 127.697 120.954 1.00 26.92 ? 294 CYS C CA  1 
ATOM   5744 C C   . CYS C 3 312 ? 152.244 127.686 120.786 1.00 22.40 ? 294 CYS C C   1 
ATOM   5745 O O   . CYS C 3 312 ? 152.936 128.537 121.349 1.00 43.68 ? 294 CYS C O   1 
ATOM   5746 C CB  . CYS C 3 312 ? 150.132 128.882 120.197 1.00 31.29 ? 294 CYS C CB  1 
ATOM   5747 S SG  . CYS C 3 312 ? 148.424 129.253 120.635 1.00 49.26 ? 294 CYS C SG  1 
ATOM   5748 N N   . ASN C 3 313 ? 152.744 126.735 120.001 1.00 25.56 ? 295 ASN C N   1 
ATOM   5749 C CA  . ASN C 3 313 ? 154.168 126.572 119.741 1.00 33.63 ? 295 ASN C CA  1 
ATOM   5750 C C   . ASN C 3 313 ? 154.486 127.084 118.346 1.00 35.52 ? 295 ASN C C   1 
ATOM   5751 O O   . ASN C 3 313 ? 153.732 126.828 117.402 1.00 42.24 ? 295 ASN C O   1 
ATOM   5752 C CB  . ASN C 3 313 ? 154.586 125.107 119.869 1.00 32.39 ? 295 ASN C CB  1 
ATOM   5753 C CG  . ASN C 3 313 ? 154.294 124.535 121.239 1.00 37.74 ? 295 ASN C CG  1 
ATOM   5754 O OD1 . ASN C 3 313 ? 153.653 125.177 122.068 1.00 39.45 ? 295 ASN C OD1 1 
ATOM   5755 N ND2 . ASN C 3 313 ? 154.761 123.319 121.483 1.00 37.03 ? 295 ASN C ND2 1 
ATOM   5756 N N   . VAL C 3 314 ? 155.602 127.798 118.222 1.00 32.50 ? 296 VAL C N   1 
ATOM   5757 C CA  . VAL C 3 314 ? 156.036 128.401 116.967 1.00 28.14 ? 296 VAL C CA  1 
ATOM   5758 C C   . VAL C 3 314 ? 157.213 127.594 116.438 1.00 30.45 ? 296 VAL C C   1 
ATOM   5759 O O   . VAL C 3 314 ? 158.261 127.516 117.090 1.00 27.53 ? 296 VAL C O   1 
ATOM   5760 C CB  . VAL C 3 314 ? 156.418 129.877 117.170 1.00 25.83 ? 296 VAL C CB  1 
ATOM   5761 C CG1 . VAL C 3 314 ? 156.988 130.463 115.892 1.00 32.55 ? 296 VAL C CG1 1 
ATOM   5762 C CG2 . VAL C 3 314 ? 155.214 130.673 117.657 1.00 25.30 ? 296 VAL C CG2 1 
ATOM   5763 N N   . TRP C 3 315 ? 157.048 127.013 115.251 1.00 31.69 ? 297 TRP C N   1 
ATOM   5764 C CA  . TRP C 3 315 ? 158.011 126.086 114.669 1.00 29.78 ? 297 TRP C CA  1 
ATOM   5765 C C   . TRP C 3 315 ? 158.750 126.752 113.521 1.00 26.87 ? 297 TRP C C   1 
ATOM   5766 O O   . TRP C 3 315 ? 158.125 127.335 112.631 1.00 37.44 ? 297 TRP C O   1 
ATOM   5767 C CB  . TRP C 3 315 ? 157.327 124.820 114.145 1.00 26.84 ? 297 TRP C CB  1 
ATOM   5768 C CG  . TRP C 3 315 ? 156.592 124.039 115.171 1.00 26.52 ? 297 TRP C CG  1 
ATOM   5769 C CD1 . TRP C 3 315 ? 155.287 124.179 115.530 1.00 21.62 ? 297 TRP C CD1 1 
ATOM   5770 C CD2 . TRP C 3 315 ? 157.118 122.977 115.969 1.00 30.48 ? 297 TRP C CD2 1 
ATOM   5771 N NE1 . TRP C 3 315 ? 154.967 123.272 116.508 1.00 31.11 ? 297 TRP C NE1 1 
ATOM   5772 C CE2 . TRP C 3 315 ? 156.077 122.522 116.795 1.00 35.86 ? 297 TRP C CE2 1 
ATOM   5773 C CE3 . TRP C 3 315 ? 158.371 122.368 116.066 1.00 25.99 ? 297 TRP C CE3 1 
ATOM   5774 C CZ2 . TRP C 3 315 ? 156.250 121.487 117.707 1.00 33.86 ? 297 TRP C CZ2 1 
ATOM   5775 C CZ3 . TRP C 3 315 ? 158.540 121.344 116.969 1.00 26.42 ? 297 TRP C CZ3 1 
ATOM   5776 C CH2 . TRP C 3 315 ? 157.487 120.913 117.779 1.00 27.65 ? 297 TRP C CH2 1 
ATOM   5777 N N   . ASP C 3 316 ? 160.073 126.652 113.536 1.00 21.05 ? 298 ASP C N   1 
ATOM   5778 C CA  . ASP C 3 316 ? 160.844 126.995 112.355 1.00 18.68 ? 298 ASP C CA  1 
ATOM   5779 C C   . ASP C 3 316 ? 160.514 125.995 111.257 1.00 28.70 ? 298 ASP C C   1 
ATOM   5780 O O   . ASP C 3 316 ? 160.990 124.856 111.277 1.00 41.11 ? 298 ASP C O   1 
ATOM   5781 C CB  . ASP C 3 316 ? 162.336 126.976 112.682 1.00 29.70 ? 298 ASP C CB  1 
ATOM   5782 C CG  . ASP C 3 316 ? 163.192 127.544 111.573 1.00 34.74 ? 298 ASP C CG  1 
ATOM   5783 O OD1 . ASP C 3 316 ? 162.637 128.090 110.599 1.00 36.11 ? 298 ASP C OD1 1 
ATOM   5784 O OD2 . ASP C 3 316 ? 164.431 127.447 111.677 1.00 33.95 ? 298 ASP C OD2 1 
ATOM   5785 N N   . ALA C 3 317 ? 159.690 126.426 110.298 1.00 36.25 ? 299 ALA C N   1 
ATOM   5786 C CA  . ALA C 3 317 ? 159.085 125.492 109.353 1.00 34.85 ? 299 ALA C CA  1 
ATOM   5787 C C   . ALA C 3 317 ? 160.130 124.829 108.467 1.00 30.05 ? 299 ALA C C   1 
ATOM   5788 O O   . ALA C 3 317 ? 159.959 123.679 108.052 1.00 35.20 ? 299 ALA C O   1 
ATOM   5789 C CB  . ALA C 3 317 ? 158.044 126.211 108.499 1.00 29.33 ? 299 ALA C CB  1 
ATOM   5790 N N   . LEU C 3 318 ? 161.214 125.537 108.160 1.00 27.16 ? 300 LEU C N   1 
ATOM   5791 C CA  . LEU C 3 318 ? 162.247 124.953 107.312 1.00 35.03 ? 300 LEU C CA  1 
ATOM   5792 C C   . LEU C 3 318 ? 163.028 123.864 108.039 1.00 38.14 ? 300 LEU C C   1 
ATOM   5793 O O   . LEU C 3 318 ? 163.376 122.846 107.432 1.00 41.21 ? 300 LEU C O   1 
ATOM   5794 C CB  . LEU C 3 318 ? 163.186 126.044 106.799 1.00 32.69 ? 300 LEU C CB  1 
ATOM   5795 C CG  . LEU C 3 318 ? 162.901 126.521 105.374 1.00 31.71 ? 300 LEU C CG  1 
ATOM   5796 C CD1 . LEU C 3 318 ? 161.485 127.044 105.212 1.00 34.83 ? 300 LEU C CD1 1 
ATOM   5797 C CD2 . LEU C 3 318 ? 163.899 127.592 104.984 1.00 36.53 ? 300 LEU C CD2 1 
ATOM   5798 N N   . LYS C 3 319 ? 163.295 124.046 109.335 1.00 33.63 ? 301 LYS C N   1 
ATOM   5799 C CA  . LYS C 3 319 ? 164.173 123.167 110.104 1.00 33.82 ? 301 LYS C CA  1 
ATOM   5800 C C   . LYS C 3 319 ? 163.446 122.297 111.124 1.00 34.88 ? 301 LYS C C   1 
ATOM   5801 O O   . LYS C 3 319 ? 164.065 121.381 111.673 1.00 39.81 ? 301 LYS C O   1 
ATOM   5802 C CB  . LYS C 3 319 ? 165.236 123.993 110.833 1.00 36.11 ? 301 LYS C CB  1 
ATOM   5803 C CG  . LYS C 3 319 ? 165.951 125.017 109.971 1.00 38.17 ? 301 LYS C CG  1 
ATOM   5804 C CD  . LYS C 3 319 ? 167.018 125.744 110.765 1.00 41.29 ? 301 LYS C CD  1 
ATOM   5805 C CE  . LYS C 3 319 ? 168.364 125.703 110.078 1.00 43.88 ? 301 LYS C CE  1 
ATOM   5806 N NZ  . LYS C 3 319 ? 169.009 124.369 110.191 1.00 42.51 ? 301 LYS C NZ  1 
ATOM   5807 N N   . ALA C 3 320 ? 162.163 122.548 111.387 1.00 31.92 ? 302 ALA C N   1 
ATOM   5808 C CA  . ALA C 3 320 ? 161.407 121.826 112.414 1.00 29.82 ? 302 ALA C CA  1 
ATOM   5809 C C   . ALA C 3 320 ? 162.067 121.944 113.784 1.00 35.05 ? 302 ALA C C   1 
ATOM   5810 O O   . ALA C 3 320 ? 162.256 120.953 114.490 1.00 43.58 ? 302 ALA C O   1 
ATOM   5811 C CB  . ALA C 3 320 ? 161.205 120.355 112.042 1.00 30.61 ? 302 ALA C CB  1 
ATOM   5812 N N   . ASP C 3 321 ? 162.431 123.169 114.148 1.00 34.26 ? 303 ASP C N   1 
ATOM   5813 C CA  . ASP C 3 321 ? 162.902 123.513 115.482 1.00 29.41 ? 303 ASP C CA  1 
ATOM   5814 C C   . ASP C 3 321 ? 161.892 124.458 116.106 1.00 27.98 ? 303 ASP C C   1 
ATOM   5815 O O   . ASP C 3 321 ? 161.489 125.439 115.475 1.00 41.89 ? 303 ASP C O   1 
ATOM   5816 C CB  . ASP C 3 321 ? 164.276 124.185 115.426 1.00 30.91 ? 303 ASP C CB  1 
ATOM   5817 C CG  . ASP C 3 321 ? 165.412 123.199 115.233 1.00 39.20 ? 303 ASP C CG  1 
ATOM   5818 O OD1 . ASP C 3 321 ? 165.171 121.975 115.259 1.00 35.68 ? 303 ASP C OD1 1 
ATOM   5819 O OD2 . ASP C 3 321 ? 166.559 123.658 115.052 1.00 37.10 ? 303 ASP C OD2 1 
ATOM   5820 N N   . ARG C 3 322 ? 161.470 124.163 117.331 1.00 31.63 ? 304 ARG C N   1 
ATOM   5821 C CA  . ARG C 3 322 ? 160.610 125.101 118.034 1.00 32.79 ? 304 ARG C CA  1 
ATOM   5822 C C   . ARG C 3 322 ? 161.379 126.381 118.324 1.00 40.59 ? 304 ARG C C   1 
ATOM   5823 O O   . ARG C 3 322 ? 162.469 126.353 118.900 1.00 44.41 ? 304 ARG C O   1 
ATOM   5824 C CB  . ARG C 3 322 ? 160.086 124.501 119.337 1.00 29.84 ? 304 ARG C CB  1 
ATOM   5825 C CG  . ARG C 3 322 ? 158.666 124.932 119.659 1.00 34.16 ? 304 ARG C CG  1 
ATOM   5826 C CD  . ARG C 3 322 ? 158.263 124.566 121.076 1.00 45.29 ? 304 ARG C CD  1 
ATOM   5827 N NE  . ARG C 3 322 ? 158.527 123.168 121.395 1.00 47.26 ? 304 ARG C NE  1 
ATOM   5828 C CZ  . ARG C 3 322 ? 158.528 122.652 122.618 1.00 45.43 ? 304 ARG C CZ  1 
ATOM   5829 N NH1 . ARG C 3 322 ? 158.285 123.390 123.691 1.00 41.25 ? 304 ARG C NH1 1 
ATOM   5830 N NH2 . ARG C 3 322 ? 158.773 121.355 122.770 1.00 41.22 ? 304 ARG C NH2 1 
ATOM   5831 N N   . ALA C 3 323 ? 160.794 127.510 117.917 1.00 38.62 ? 305 ALA C N   1 
ATOM   5832 C CA  . ALA C 3 323 ? 161.399 128.822 118.087 1.00 32.55 ? 305 ALA C CA  1 
ATOM   5833 C C   . ALA C 3 323 ? 160.772 129.638 119.204 1.00 38.48 ? 305 ALA C C   1 
ATOM   5834 O O   . ALA C 3 323 ? 161.402 130.588 119.675 1.00 40.81 ? 305 ALA C O   1 
ATOM   5835 C CB  . ALA C 3 323 ? 161.304 129.620 116.779 1.00 30.88 ? 305 ALA C CB  1 
ATOM   5836 N N   . GLY C 3 324 ? 159.563 129.303 119.637 1.00 32.66 ? 306 GLY C N   1 
ATOM   5837 C CA  . GLY C 3 324 ? 158.932 130.041 120.713 1.00 29.18 ? 306 GLY C CA  1 
ATOM   5838 C C   . GLY C 3 324 ? 157.652 129.373 121.151 1.00 30.25 ? 306 GLY C C   1 
ATOM   5839 O O   . GLY C 3 324 ? 157.182 128.414 120.532 1.00 36.18 ? 306 GLY C O   1 
ATOM   5840 N N   . VAL C 3 325 ? 157.101 129.886 122.246 1.00 27.74 ? 307 VAL C N   1 
ATOM   5841 C CA  . VAL C 3 325 ? 155.823 129.444 122.788 1.00 23.32 ? 307 VAL C CA  1 
ATOM   5842 C C   . VAL C 3 325 ? 155.020 130.679 123.163 1.00 26.59 ? 307 VAL C C   1 
ATOM   5843 O O   . VAL C 3 325 ? 155.564 131.629 123.736 1.00 46.03 ? 307 VAL C O   1 
ATOM   5844 C CB  . VAL C 3 325 ? 156.011 128.519 124.010 1.00 33.98 ? 307 VAL C CB  1 
ATOM   5845 C CG1 . VAL C 3 325 ? 154.675 128.238 124.687 1.00 32.40 ? 307 VAL C CG1 1 
ATOM   5846 C CG2 . VAL C 3 325 ? 156.690 127.218 123.597 1.00 34.76 ? 307 VAL C CG2 1 
ATOM   5847 N N   . LEU C 3 326 ? 153.732 130.669 122.828 1.00 22.21 ? 308 LEU C N   1 
ATOM   5848 C CA  . LEU C 3 326 ? 152.791 131.716 123.213 1.00 24.75 ? 308 LEU C CA  1 
ATOM   5849 C C   . LEU C 3 326 ? 151.824 131.130 124.230 1.00 33.52 ? 308 LEU C C   1 
ATOM   5850 O O   . LEU C 3 326 ? 150.957 130.325 123.875 1.00 33.23 ? 308 LEU C O   1 
ATOM   5851 C CB  . LEU C 3 326 ? 152.043 132.270 121.997 1.00 28.59 ? 308 LEU C CB  1 
ATOM   5852 C CG  . LEU C 3 326 ? 152.808 132.377 120.675 1.00 33.83 ? 308 LEU C CG  1 
ATOM   5853 C CD1 . LEU C 3 326 ? 151.892 132.881 119.574 1.00 29.10 ? 308 LEU C CD1 1 
ATOM   5854 C CD2 . LEU C 3 326 ? 154.025 133.278 120.814 1.00 35.97 ? 308 LEU C CD2 1 
ATOM   5855 N N   . ALA C 3 327 ? 151.979 131.534 125.491 1.00 42.57 ? 309 ALA C N   1 
ATOM   5856 C CA  . ALA C 3 327 ? 151.204 130.997 126.607 1.00 38.68 ? 309 ALA C CA  1 
ATOM   5857 C C   . ALA C 3 327 ? 150.605 132.159 127.385 1.00 38.53 ? 309 ALA C C   1 
ATOM   5858 O O   . ALA C 3 327 ? 151.308 132.828 128.147 1.00 39.16 ? 309 ALA C O   1 
ATOM   5859 C CB  . ALA C 3 327 ? 152.077 130.129 127.512 1.00 35.80 ? 309 ALA C CB  1 
ATOM   5860 N N   . GLY C 3 328 ? 149.316 132.408 127.170 1.00 35.52 ? 310 GLY C N   1 
ATOM   5861 C CA  . GLY C 3 328 ? 148.572 133.377 127.950 1.00 30.12 ? 310 GLY C CA  1 
ATOM   5862 C C   . GLY C 3 328 ? 147.120 133.000 128.178 1.00 36.95 ? 310 GLY C C   1 
ATOM   5863 O O   . GLY C 3 328 ? 146.343 133.824 128.671 1.00 38.91 ? 310 GLY C O   1 
ATOM   5864 N N   . HIS C 3 329 ? 146.745 131.766 127.844 1.00 35.94 ? 311 HIS C N   1 
ATOM   5865 C CA  . HIS C 3 329 ? 145.354 131.335 127.773 1.00 39.10 ? 311 HIS C CA  1 
ATOM   5866 C C   . HIS C 3 329 ? 145.052 130.358 128.900 1.00 39.34 ? 311 HIS C C   1 
ATOM   5867 O O   . HIS C 3 329 ? 145.867 129.481 129.206 1.00 43.29 ? 311 HIS C O   1 
ATOM   5868 C CB  . HIS C 3 329 ? 145.066 130.686 126.415 1.00 35.55 ? 311 HIS C CB  1 
ATOM   5869 C CG  . HIS C 3 329 ? 144.829 131.664 125.301 1.00 38.81 ? 311 HIS C CG  1 
ATOM   5870 N ND1 . HIS C 3 329 ? 144.139 132.845 125.471 1.00 42.36 ? 311 HIS C ND1 1 
ATOM   5871 C CD2 . HIS C 3 329 ? 145.205 131.636 124.002 1.00 33.10 ? 311 HIS C CD2 1 
ATOM   5872 C CE1 . HIS C 3 329 ? 144.088 133.494 124.322 1.00 35.31 ? 311 HIS C CE1 1 
ATOM   5873 N NE2 . HIS C 3 329 ? 144.730 132.783 123.415 1.00 29.13 ? 311 HIS C NE2 1 
ATOM   5874 N N   . ASP C 3 330 ? 143.881 130.523 129.520 1.00 50.34 ? 312 ASP C N   1 
ATOM   5875 C CA  . ASP C 3 330 ? 143.485 129.647 130.618 1.00 49.08 ? 312 ASP C CA  1 
ATOM   5876 C C   . ASP C 3 330 ? 143.052 128.276 130.112 1.00 46.49 ? 312 ASP C C   1 
ATOM   5877 O O   . ASP C 3 330 ? 143.271 127.264 130.788 1.00 55.32 ? 312 ASP C O   1 
ATOM   5878 C CB  . ASP C 3 330 ? 142.357 130.297 131.420 1.00 50.66 ? 312 ASP C CB  1 
ATOM   5879 C CG  . ASP C 3 330 ? 142.277 129.784 132.845 1.00 55.39 ? 312 ASP C CG  1 
ATOM   5880 O OD1 . ASP C 3 330 ? 142.876 128.730 133.144 1.00 56.77 ? 312 ASP C OD1 1 
ATOM   5881 O OD2 . ASP C 3 330 ? 141.606 130.438 133.671 1.00 55.56 ? 312 ASP C OD2 1 
ATOM   5882 N N   . ASN C 3 331 ? 142.432 128.226 128.931 1.00 35.20 ? 313 ASN C N   1 
ATOM   5883 C CA  . ASN C 3 331 ? 141.870 127.012 128.351 1.00 38.85 ? 313 ASN C CA  1 
ATOM   5884 C C   . ASN C 3 331 ? 142.452 126.825 126.954 1.00 43.39 ? 313 ASN C C   1 
ATOM   5885 O O   . ASN C 3 331 ? 143.310 127.594 126.514 1.00 40.74 ? 313 ASN C O   1 
ATOM   5886 C CB  . ASN C 3 331 ? 140.334 127.090 128.317 1.00 39.82 ? 313 ASN C CB  1 
ATOM   5887 C CG  . ASN C 3 331 ? 139.659 125.730 128.451 1.00 41.85 ? 313 ASN C CG  1 
ATOM   5888 O OD1 . ASN C 3 331 ? 140.303 124.683 128.402 1.00 43.34 ? 313 ASN C OD1 1 
ATOM   5889 N ND2 . ASN C 3 331 ? 138.344 125.748 128.627 1.00 43.53 ? 313 ASN C ND2 1 
ATOM   5890 N N   . ARG C 3 332 ? 141.997 125.776 126.265 1.00 39.29 ? 314 ARG C N   1 
ATOM   5891 C CA  . ARG C 3 332 ? 142.585 125.400 124.983 1.00 36.08 ? 314 ARG C CA  1 
ATOM   5892 C C   . ARG C 3 332 ? 142.365 126.493 123.948 1.00 37.67 ? 314 ARG C C   1 
ATOM   5893 O O   . ARG C 3 332 ? 141.364 127.211 123.990 1.00 44.73 ? 314 ARG C O   1 
ATOM   5894 C CB  . ARG C 3 332 ? 141.982 124.084 124.482 1.00 34.19 ? 314 ARG C CB  1 
ATOM   5895 C CG  . ARG C 3 332 ? 140.540 124.179 123.992 1.00 33.13 ? 314 ARG C CG  1 
ATOM   5896 C CD  . ARG C 3 332 ? 139.919 122.811 123.773 1.00 41.35 ? 314 ARG C CD  1 
ATOM   5897 N NE  . ARG C 3 332 ? 140.409 122.106 122.594 1.00 40.61 ? 314 ARG C NE  1 
ATOM   5898 C CZ  . ARG C 3 332 ? 140.005 122.321 121.347 1.00 42.60 ? 314 ARG C CZ  1 
ATOM   5899 N NH1 . ARG C 3 332 ? 139.180 123.309 121.037 1.00 47.45 ? 314 ARG C NH1 1 
ATOM   5900 N NH2 . ARG C 3 332 ? 140.440 121.520 120.380 1.00 41.29 ? 314 ARG C NH2 1 
ATOM   5901 N N   . VAL C 3 333 ? 143.305 126.616 123.015 1.00 34.96 ? 315 VAL C N   1 
ATOM   5902 C CA  . VAL C 3 333 ? 143.176 127.561 121.912 1.00 35.55 ? 315 VAL C CA  1 
ATOM   5903 C C   . VAL C 3 333 ? 142.326 126.896 120.832 1.00 41.36 ? 315 VAL C C   1 
ATOM   5904 O O   . VAL C 3 333 ? 142.658 125.821 120.327 1.00 31.65 ? 315 VAL C O   1 
ATOM   5905 C CB  . VAL C 3 333 ? 144.541 128.027 121.384 1.00 23.78 ? 315 VAL C CB  1 
ATOM   5906 C CG1 . VAL C 3 333 ? 145.364 128.579 122.518 1.00 40.02 ? 315 VAL C CG1 1 
ATOM   5907 C CG2 . VAL C 3 333 ? 145.315 126.927 120.691 1.00 32.22 ? 315 VAL C CG2 1 
ATOM   5908 N N   . SER C 3 334 ? 141.180 127.508 120.531 1.00 34.60 ? 316 SER C N   1 
ATOM   5909 C CA  . SER C 3 334 ? 140.285 126.958 119.521 1.00 23.21 ? 316 SER C CA  1 
ATOM   5910 C C   . SER C 3 334 ? 140.715 127.363 118.118 1.00 32.59 ? 316 SER C C   1 
ATOM   5911 O O   . SER C 3 334 ? 140.605 126.567 117.178 1.00 37.15 ? 316 SER C O   1 
ATOM   5912 C CB  . SER C 3 334 ? 138.858 127.414 119.797 1.00 25.26 ? 316 SER C CB  1 
ATOM   5913 O OG  . SER C 3 334 ? 138.841 128.693 120.400 1.00 27.52 ? 316 SER C OG  1 
ATOM   5914 N N   . CYS C 3 335 ? 141.196 128.596 117.956 1.00 27.62 ? 317 CYS C N   1 
ATOM   5915 C CA  . CYS C 3 335 ? 141.506 129.160 116.651 1.00 20.28 ? 317 CYS C CA  1 
ATOM   5916 C C   . CYS C 3 335 ? 142.814 129.930 116.714 1.00 23.42 ? 317 CYS C C   1 
ATOM   5917 O O   . CYS C 3 335 ? 143.234 130.392 117.776 1.00 32.99 ? 317 CYS C O   1 
ATOM   5918 C CB  . CYS C 3 335 ? 140.401 130.094 116.167 1.00 20.78 ? 317 CYS C CB  1 
ATOM   5919 S SG  . CYS C 3 335 ? 139.659 131.075 117.483 1.00 45.82 ? 317 CYS C SG  1 
ATOM   5920 N N   . LEU C 3 336 ? 143.455 130.049 115.557 1.00 27.55 ? 318 LEU C N   1 
ATOM   5921 C CA  . LEU C 3 336 ? 144.699 130.784 115.397 1.00 22.34 ? 318 LEU C CA  1 
ATOM   5922 C C   . LEU C 3 336 ? 144.703 131.409 114.010 1.00 27.99 ? 318 LEU C C   1 
ATOM   5923 O O   . LEU C 3 336 ? 144.319 130.760 113.033 1.00 39.49 ? 318 LEU C O   1 
ATOM   5924 C CB  . LEU C 3 336 ? 145.902 129.847 115.590 1.00 17.85 ? 318 LEU C CB  1 
ATOM   5925 C CG  . LEU C 3 336 ? 147.304 130.440 115.767 1.00 20.39 ? 318 LEU C CG  1 
ATOM   5926 C CD1 . LEU C 3 336 ? 148.236 129.409 116.388 1.00 24.96 ? 318 LEU C CD1 1 
ATOM   5927 C CD2 . LEU C 3 336 ? 147.888 130.966 114.467 1.00 24.54 ? 318 LEU C CD2 1 
ATOM   5928 N N   . GLY C 3 337 ? 145.120 132.666 113.930 1.00 17.38 ? 319 GLY C N   1 
ATOM   5929 C CA  . GLY C 3 337 ? 145.180 133.366 112.659 1.00 19.82 ? 319 GLY C CA  1 
ATOM   5930 C C   . GLY C 3 337 ? 146.320 134.360 112.636 1.00 14.58 ? 319 GLY C C   1 
ATOM   5931 O O   . GLY C 3 337 ? 146.674 134.954 113.654 1.00 32.45 ? 319 GLY C O   1 
ATOM   5932 N N   . VAL C 3 338 ? 146.885 134.540 111.444 1.00 17.13 ? 320 VAL C N   1 
ATOM   5933 C CA  . VAL C 3 338 ? 148.013 135.433 111.204 1.00 19.66 ? 320 VAL C CA  1 
ATOM   5934 C C   . VAL C 3 338 ? 147.563 136.500 110.219 1.00 24.62 ? 320 VAL C C   1 
ATOM   5935 O O   . VAL C 3 338 ? 146.867 136.199 109.243 1.00 37.42 ? 320 VAL C O   1 
ATOM   5936 C CB  . VAL C 3 338 ? 149.241 134.673 110.669 1.00 27.50 ? 320 VAL C CB  1 
ATOM   5937 C CG1 . VAL C 3 338 ? 150.354 135.641 110.307 1.00 14.71 ? 320 VAL C CG1 1 
ATOM   5938 C CG2 . VAL C 3 338 ? 149.735 133.660 111.695 1.00 32.01 ? 320 VAL C CG2 1 
ATOM   5939 N N   . THR C 3 339 ? 147.959 137.741 110.479 1.00 24.80 ? 321 THR C N   1 
ATOM   5940 C CA  . THR C 3 339 ? 147.467 138.876 109.716 1.00 13.82 ? 321 THR C CA  1 
ATOM   5941 C C   . THR C 3 339 ? 147.969 138.816 108.275 1.00 23.04 ? 321 THR C C   1 
ATOM   5942 O O   . THR C 3 339 ? 149.032 138.262 107.988 1.00 34.34 ? 321 THR C O   1 
ATOM   5943 C CB  . THR C 3 339 ? 147.915 140.175 110.385 1.00 16.69 ? 321 THR C CB  1 
ATOM   5944 O OG1 . THR C 3 339 ? 147.632 140.108 111.786 1.00 28.44 ? 321 THR C OG1 1 
ATOM   5945 C CG2 . THR C 3 339 ? 147.191 141.350 109.817 1.00 20.55 ? 321 THR C CG2 1 
ATOM   5946 N N   . ASP C 3 340 ? 147.178 139.388 107.361 1.00 30.84 ? 322 ASP C N   1 
ATOM   5947 C CA  . ASP C 3 340 ? 147.540 139.366 105.946 1.00 32.05 ? 322 ASP C CA  1 
ATOM   5948 C C   . ASP C 3 340 ? 148.817 140.154 105.686 1.00 27.17 ? 322 ASP C C   1 
ATOM   5949 O O   . ASP C 3 340 ? 149.690 139.704 104.935 1.00 29.38 ? 322 ASP C O   1 
ATOM   5950 C CB  . ASP C 3 340 ? 146.397 139.925 105.104 1.00 32.23 ? 322 ASP C CB  1 
ATOM   5951 C CG  . ASP C 3 340 ? 145.115 139.146 105.276 1.00 36.93 ? 322 ASP C CG  1 
ATOM   5952 O OD1 . ASP C 3 340 ? 144.637 139.036 106.424 1.00 38.04 ? 322 ASP C OD1 1 
ATOM   5953 O OD2 . ASP C 3 340 ? 144.585 138.647 104.263 1.00 28.38 ? 322 ASP C OD2 1 
ATOM   5954 N N   . ASP C 3 341 ? 148.942 141.338 106.289 1.00 19.81 ? 323 ASP C N   1 
ATOM   5955 C CA  . ASP C 3 341 ? 150.201 142.073 106.206 1.00 23.39 ? 323 ASP C CA  1 
ATOM   5956 C C   . ASP C 3 341 ? 151.319 141.358 106.960 1.00 30.83 ? 323 ASP C C   1 
ATOM   5957 O O   . ASP C 3 341 ? 152.502 141.595 106.694 1.00 33.59 ? 323 ASP C O   1 
ATOM   5958 C CB  . ASP C 3 341 ? 150.012 143.513 106.705 1.00 25.63 ? 323 ASP C CB  1 
ATOM   5959 C CG  . ASP C 3 341 ? 149.507 143.606 108.148 1.00 34.12 ? 323 ASP C CG  1 
ATOM   5960 O OD1 . ASP C 3 341 ? 149.826 142.752 108.999 1.00 36.97 ? 323 ASP C OD1 1 
ATOM   5961 O OD2 . ASP C 3 341 ? 148.775 144.576 108.437 1.00 34.06 ? 323 ASP C OD2 1 
ATOM   5962 N N   . GLY C 3 342 ? 150.966 140.501 107.917 1.00 30.60 ? 324 GLY C N   1 
ATOM   5963 C CA  . GLY C 3 342 ? 151.930 139.735 108.675 1.00 24.67 ? 324 GLY C CA  1 
ATOM   5964 C C   . GLY C 3 342 ? 152.356 140.362 109.979 1.00 29.34 ? 324 GLY C C   1 
ATOM   5965 O O   . GLY C 3 342 ? 153.275 139.845 110.619 1.00 36.10 ? 324 GLY C O   1 
ATOM   5966 N N   . MET C 3 343 ? 151.718 141.454 110.400 1.00 29.59 ? 325 MET C N   1 
ATOM   5967 C CA  . MET C 3 343 ? 152.191 142.172 111.577 1.00 28.86 ? 325 MET C CA  1 
ATOM   5968 C C   . MET C 3 343 ? 151.939 141.390 112.859 1.00 29.65 ? 325 MET C C   1 
ATOM   5969 O O   . MET C 3 343 ? 152.796 141.366 113.750 1.00 38.85 ? 325 MET C O   1 
ATOM   5970 C CB  . MET C 3 343 ? 151.523 143.542 111.661 1.00 32.16 ? 325 MET C CB  1 
ATOM   5971 C CG  . MET C 3 343 ? 152.404 144.623 112.281 1.00 41.19 ? 325 MET C CG  1 
ATOM   5972 S SD  . MET C 3 343 ? 153.876 145.169 111.375 1.00 37.17 ? 325 MET C SD  1 
ATOM   5973 C CE  . MET C 3 343 ? 153.326 145.225 109.673 1.00 31.68 ? 325 MET C CE  1 
ATOM   5974 N N   . ALA C 3 344 ? 150.777 140.745 112.972 1.00 27.50 ? 326 ALA C N   1 
ATOM   5975 C CA  . ALA C 3 344 ? 150.295 140.236 114.248 1.00 22.96 ? 326 ALA C CA  1 
ATOM   5976 C C   . ALA C 3 344 ? 149.656 138.867 114.081 1.00 11.37 ? 326 ALA C C   1 
ATOM   5977 O O   . ALA C 3 344 ? 149.222 138.483 112.994 1.00 27.93 ? 326 ALA C O   1 
ATOM   5978 C CB  . ALA C 3 344 ? 149.285 141.199 114.874 1.00 30.90 ? 326 ALA C CB  1 
ATOM   5979 N N   . VAL C 3 345 ? 149.612 138.140 115.196 1.00 20.72 ? 327 VAL C N   1 
ATOM   5980 C CA  . VAL C 3 345 ? 148.949 136.847 115.316 1.00 20.56 ? 327 VAL C CA  1 
ATOM   5981 C C   . VAL C 3 345 ? 147.834 137.001 116.335 1.00 13.22 ? 327 VAL C C   1 
ATOM   5982 O O   . VAL C 3 345 ? 148.070 137.492 117.444 1.00 37.89 ? 327 VAL C O   1 
ATOM   5983 C CB  . VAL C 3 345 ? 149.928 135.741 115.758 1.00 18.95 ? 327 VAL C CB  1 
ATOM   5984 C CG1 . VAL C 3 345 ? 149.299 134.359 115.601 1.00 20.22 ? 327 VAL C CG1 1 
ATOM   5985 C CG2 . VAL C 3 345 ? 151.221 135.830 114.973 1.00 26.25 ? 327 VAL C CG2 1 
ATOM   5986 N N   . ALA C 3 346 ? 146.629 136.578 115.964 1.00 1.94  ? 328 ALA C N   1 
ATOM   5987 C CA  . ALA C 3 346 ? 145.482 136.554 116.859 1.00 13.17 ? 328 ALA C CA  1 
ATOM   5988 C C   . ALA C 3 346 ? 145.131 135.114 117.185 1.00 14.64 ? 328 ALA C C   1 
ATOM   5989 O O   . ALA C 3 346 ? 145.029 134.274 116.288 1.00 30.61 ? 328 ALA C O   1 
ATOM   5990 C CB  . ALA C 3 346 ? 144.277 137.255 116.241 1.00 22.82 ? 328 ALA C CB  1 
ATOM   5991 N N   . THR C 3 347 ? 144.962 134.838 118.476 1.00 18.92 ? 329 THR C N   1 
ATOM   5992 C CA  . THR C 3 347 ? 144.581 133.525 118.973 1.00 24.71 ? 329 THR C CA  1 
ATOM   5993 C C   . THR C 3 347 ? 143.297 133.665 119.771 1.00 25.18 ? 329 THR C C   1 
ATOM   5994 O O   . THR C 3 347 ? 143.074 134.680 120.431 1.00 38.30 ? 329 THR C O   1 
ATOM   5995 C CB  . THR C 3 347 ? 145.665 132.895 119.871 1.00 25.49 ? 329 THR C CB  1 
ATOM   5996 O OG1 . THR C 3 347 ? 145.802 133.655 121.075 1.00 28.72 ? 329 THR C OG1 1 
ATOM   5997 C CG2 . THR C 3 347 ? 147.010 132.847 119.168 1.00 21.30 ? 329 THR C CG2 1 
ATOM   5998 N N   . GLY C 3 348 ? 142.458 132.641 119.685 1.00 26.45 ? 330 GLY C N   1 
ATOM   5999 C CA  . GLY C 3 348 ? 141.258 132.561 120.493 1.00 22.76 ? 330 GLY C CA  1 
ATOM   6000 C C   . GLY C 3 348 ? 141.245 131.250 121.246 1.00 25.35 ? 330 GLY C C   1 
ATOM   6001 O O   . GLY C 3 348 ? 141.841 130.263 120.820 1.00 36.31 ? 330 GLY C O   1 
ATOM   6002 N N   . SER C 3 349 ? 140.568 131.258 122.393 1.00 32.15 ? 331 SER C N   1 
ATOM   6003 C CA  . SER C 3 349 ? 140.564 130.108 123.284 1.00 33.76 ? 331 SER C CA  1 
ATOM   6004 C C   . SER C 3 349 ? 139.217 129.986 123.974 1.00 32.05 ? 331 SER C C   1 
ATOM   6005 O O   . SER C 3 349 ? 138.376 130.886 123.918 1.00 38.38 ? 331 SER C O   1 
ATOM   6006 C CB  . SER C 3 349 ? 141.682 130.202 124.330 1.00 35.89 ? 331 SER C CB  1 
ATOM   6007 O OG  . SER C 3 349 ? 141.767 131.506 124.864 1.00 42.85 ? 331 SER C OG  1 
ATOM   6008 N N   . TRP C 3 350 ? 139.024 128.837 124.620 1.00 36.38 ? 332 TRP C N   1 
ATOM   6009 C CA  . TRP C 3 350 ? 137.794 128.545 125.342 1.00 41.06 ? 332 TRP C CA  1 
ATOM   6010 C C   . TRP C 3 350 ? 137.689 129.284 126.670 1.00 46.95 ? 332 TRP C C   1 
ATOM   6011 O O   . TRP C 3 350 ? 136.649 129.183 127.328 1.00 47.06 ? 332 TRP C O   1 
ATOM   6012 C CB  . TRP C 3 350 ? 137.681 127.031 125.558 1.00 37.53 ? 332 TRP C CB  1 
ATOM   6013 C CG  . TRP C 3 350 ? 137.280 126.250 124.324 1.00 38.91 ? 332 TRP C CG  1 
ATOM   6014 C CD1 . TRP C 3 350 ? 137.217 126.711 123.040 1.00 43.22 ? 332 TRP C CD1 1 
ATOM   6015 C CD2 . TRP C 3 350 ? 136.913 124.866 124.264 1.00 46.52 ? 332 TRP C CD2 1 
ATOM   6016 N NE1 . TRP C 3 350 ? 136.817 125.711 122.194 1.00 41.80 ? 332 TRP C NE1 1 
ATOM   6017 C CE2 . TRP C 3 350 ? 136.627 124.567 122.919 1.00 50.52 ? 332 TRP C CE2 1 
ATOM   6018 C CE3 . TRP C 3 350 ? 136.791 123.853 125.218 1.00 39.38 ? 332 TRP C CE3 1 
ATOM   6019 C CZ2 . TRP C 3 350 ? 136.232 123.300 122.503 1.00 50.35 ? 332 TRP C CZ2 1 
ATOM   6020 C CZ3 . TRP C 3 350 ? 136.406 122.594 124.798 1.00 41.22 ? 332 TRP C CZ3 1 
ATOM   6021 C CH2 . TRP C 3 350 ? 136.123 122.330 123.457 1.00 47.34 ? 332 TRP C CH2 1 
ATOM   6022 N N   . ASP C 3 351 ? 138.730 130.017 127.081 1.00 40.03 ? 333 ASP C N   1 
ATOM   6023 C CA  . ASP C 3 351 ? 138.601 130.921 128.220 1.00 41.25 ? 333 ASP C CA  1 
ATOM   6024 C C   . ASP C 3 351 ? 137.837 132.202 127.875 1.00 40.72 ? 333 ASP C C   1 
ATOM   6025 O O   . ASP C 3 351 ? 137.660 133.058 128.749 1.00 41.69 ? 333 ASP C O   1 
ATOM   6026 C CB  . ASP C 3 351 ? 139.987 131.243 128.785 1.00 41.47 ? 333 ASP C CB  1 
ATOM   6027 C CG  . ASP C 3 351 ? 140.842 132.079 127.846 1.00 44.39 ? 333 ASP C CG  1 
ATOM   6028 O OD1 . ASP C 3 351 ? 140.492 132.232 126.657 1.00 42.96 ? 333 ASP C OD1 1 
ATOM   6029 O OD2 . ASP C 3 351 ? 141.883 132.594 128.304 1.00 44.83 ? 333 ASP C OD2 1 
ATOM   6030 N N   . SER C 3 352 ? 137.429 132.374 126.608 1.00 35.82 ? 334 SER C N   1 
ATOM   6031 C CA  . SER C 3 352 ? 136.569 133.463 126.144 1.00 32.00 ? 334 SER C CA  1 
ATOM   6032 C C   . SER C 3 352 ? 137.308 134.788 125.975 1.00 37.40 ? 334 SER C C   1 
ATOM   6033 O O   . SER C 3 352 ? 136.664 135.831 125.827 1.00 50.78 ? 334 SER C O   1 
ATOM   6034 C CB  . SER C 3 352 ? 135.373 133.662 127.080 1.00 41.21 ? 334 SER C CB  1 
ATOM   6035 O OG  . SER C 3 352 ? 135.690 134.553 128.135 1.00 44.08 ? 334 SER C OG  1 
ATOM   6036 N N   . PHE C 3 353 ? 138.640 134.768 126.002 1.00 33.91 ? 335 PHE C N   1 
ATOM   6037 C CA  . PHE C 3 353 ? 139.469 135.922 125.675 1.00 35.81 ? 335 PHE C CA  1 
ATOM   6038 C C   . PHE C 3 353 ? 140.350 135.565 124.488 1.00 35.04 ? 335 PHE C C   1 
ATOM   6039 O O   . PHE C 3 353 ? 141.055 134.551 124.526 1.00 40.17 ? 335 PHE C O   1 
ATOM   6040 C CB  . PHE C 3 353 ? 140.340 136.334 126.864 1.00 37.45 ? 335 PHE C CB  1 
ATOM   6041 C CG  . PHE C 3 353 ? 139.561 136.672 128.099 1.00 39.84 ? 335 PHE C CG  1 
ATOM   6042 C CD1 . PHE C 3 353 ? 138.737 137.781 128.132 1.00 38.97 ? 335 PHE C CD1 1 
ATOM   6043 C CD2 . PHE C 3 353 ? 139.656 135.882 129.230 1.00 37.28 ? 335 PHE C CD2 1 
ATOM   6044 C CE1 . PHE C 3 353 ? 138.018 138.093 129.267 1.00 40.14 ? 335 PHE C CE1 1 
ATOM   6045 C CE2 . PHE C 3 353 ? 138.941 136.189 130.367 1.00 38.94 ? 335 PHE C CE2 1 
ATOM   6046 C CZ  . PHE C 3 353 ? 138.121 137.297 130.385 1.00 41.39 ? 335 PHE C CZ  1 
ATOM   6047 N N   . LEU C 3 354 ? 140.309 136.394 123.446 1.00 27.98 ? 336 LEU C N   1 
ATOM   6048 C CA  . LEU C 3 354 ? 141.166 136.241 122.277 1.00 26.85 ? 336 LEU C CA  1 
ATOM   6049 C C   . LEU C 3 354 ? 142.184 137.371 122.280 1.00 25.05 ? 336 LEU C C   1 
ATOM   6050 O O   . LEU C 3 354 ? 141.826 138.531 122.502 1.00 36.89 ? 336 LEU C O   1 
ATOM   6051 C CB  . LEU C 3 354 ? 140.353 136.232 120.977 1.00 24.21 ? 336 LEU C CB  1 
ATOM   6052 C CG  . LEU C 3 354 ? 139.512 137.435 120.550 1.00 25.19 ? 336 LEU C CG  1 
ATOM   6053 C CD1 . LEU C 3 354 ? 140.295 138.366 119.626 1.00 35.68 ? 336 LEU C CD1 1 
ATOM   6054 C CD2 . LEU C 3 354 ? 138.236 136.967 119.880 1.00 24.44 ? 336 LEU C CD2 1 
ATOM   6055 N N   . LYS C 3 355 ? 143.446 137.024 122.036 1.00 22.74 ? 337 LYS C N   1 
ATOM   6056 C CA  . LYS C 3 355 ? 144.578 137.911 122.258 1.00 26.47 ? 337 LYS C CA  1 
ATOM   6057 C C   . LYS C 3 355 ? 145.356 138.084 120.966 1.00 19.86 ? 337 LYS C C   1 
ATOM   6058 O O   . LYS C 3 355 ? 145.439 137.164 120.151 1.00 34.41 ? 337 LYS C O   1 
ATOM   6059 C CB  . LYS C 3 355 ? 145.508 137.352 123.336 1.00 38.08 ? 337 LYS C CB  1 
ATOM   6060 C CG  . LYS C 3 355 ? 144.823 137.092 124.662 1.00 40.37 ? 337 LYS C CG  1 
ATOM   6061 C CD  . LYS C 3 355 ? 145.809 136.630 125.716 1.00 30.10 ? 337 LYS C CD  1 
ATOM   6062 C CE  . LYS C 3 355 ? 145.154 136.541 127.079 1.00 28.22 ? 337 LYS C CE  1 
ATOM   6063 N NZ  . LYS C 3 355 ? 146.150 136.347 128.162 1.00 33.62 ? 337 LYS C NZ  1 
ATOM   6064 N N   . ILE C 3 356 ? 145.941 139.269 120.801 1.00 23.89 ? 338 ILE C N   1 
ATOM   6065 C CA  . ILE C 3 356 ? 146.734 139.625 119.628 1.00 23.47 ? 338 ILE C CA  1 
ATOM   6066 C C   . ILE C 3 356 ? 148.194 139.697 120.053 1.00 14.38 ? 338 ILE C C   1 
ATOM   6067 O O   . ILE C 3 356 ? 148.524 140.354 121.046 1.00 28.00 ? 338 ILE C O   1 
ATOM   6068 C CB  . ILE C 3 356 ? 146.264 140.954 119.009 1.00 29.51 ? 338 ILE C CB  1 
ATOM   6069 C CG1 . ILE C 3 356 ? 144.872 140.797 118.388 1.00 25.49 ? 338 ILE C CG1 1 
ATOM   6070 C CG2 . ILE C 3 356 ? 147.244 141.435 117.954 1.00 23.96 ? 338 ILE C CG2 1 
ATOM   6071 C CD1 . ILE C 3 356 ? 144.012 142.019 118.534 1.00 31.83 ? 338 ILE C CD1 1 
ATOM   6072 N N   . TRP C 3 357 ? 149.060 139.027 119.295 1.00 16.62 ? 339 TRP C N   1 
ATOM   6073 C CA  . TRP C 3 357 ? 150.468 138.844 119.629 1.00 23.80 ? 339 TRP C CA  1 
ATOM   6074 C C   . TRP C 3 357 ? 151.317 139.419 118.507 1.00 28.36 ? 339 TRP C C   1 
ATOM   6075 O O   . TRP C 3 357 ? 151.000 139.228 117.330 1.00 42.36 ? 339 TRP C O   1 
ATOM   6076 C CB  . TRP C 3 357 ? 150.821 137.362 119.836 1.00 20.08 ? 339 TRP C CB  1 
ATOM   6077 C CG  . TRP C 3 357 ? 149.878 136.569 120.715 1.00 24.77 ? 339 TRP C CG  1 
ATOM   6078 C CD1 . TRP C 3 357 ? 148.596 136.191 120.431 1.00 28.10 ? 339 TRP C CD1 1 
ATOM   6079 C CD2 . TRP C 3 357 ? 150.162 136.055 122.020 1.00 33.04 ? 339 TRP C CD2 1 
ATOM   6080 N NE1 . TRP C 3 357 ? 148.066 135.486 121.478 1.00 29.48 ? 339 TRP C NE1 1 
ATOM   6081 C CE2 . TRP C 3 357 ? 149.008 135.385 122.466 1.00 30.67 ? 339 TRP C CE2 1 
ATOM   6082 C CE3 . TRP C 3 357 ? 151.281 136.098 122.854 1.00 30.19 ? 339 TRP C CE3 1 
ATOM   6083 C CZ2 . TRP C 3 357 ? 148.940 134.763 123.707 1.00 28.15 ? 339 TRP C CZ2 1 
ATOM   6084 C CZ3 . TRP C 3 357 ? 151.212 135.481 124.085 1.00 32.80 ? 339 TRP C CZ3 1 
ATOM   6085 C CH2 . TRP C 3 357 ? 150.050 134.822 124.500 1.00 37.42 ? 339 TRP C CH2 1 
ATOM   6086 N N   . ASN C 3 358 ? 152.390 140.112 118.874 1.00 31.08 ? 340 ASN C N   1 
ATOM   6087 C CA  . ASN C 3 358 ? 153.253 140.786 117.907 1.00 32.63 ? 340 ASN C CA  1 
ATOM   6088 C C   . ASN C 3 358 ? 154.716 140.671 118.317 1.00 38.34 ? 340 ASN C C   1 
ATOM   6089 O O   . ASN C 3 358 ? 155.604 140.552 117.475 1.00 36.45 ? 340 ASN C O   1 
ATOM   6090 C CB  . ASN C 3 358 ? 152.857 142.256 117.782 1.00 35.33 ? 340 ASN C CB  1 
ATOM   6091 C CG  . ASN C 3 358 ? 153.415 142.911 116.538 1.00 41.21 ? 340 ASN C CG  1 
ATOM   6092 O OD1 . ASN C 3 358 ? 154.311 142.378 115.887 1.00 41.68 ? 340 ASN C OD1 1 
ATOM   6093 N ND2 . ASN C 3 358 ? 152.888 144.080 116.204 1.00 40.31 ? 340 ASN C ND2 1 
ATOM   6094 O OXT . ASN C 3 358 ? 155.047 140.696 119.500 1.00 39.92 ? 340 ASN C OXT 1 
ATOM   6095 N N   . ALA D 4 12  ? 133.569 100.772 94.253  1.00 72.16 ? 12  ALA D N   1 
ATOM   6096 C CA  . ALA D 4 12  ? 134.918 100.322 93.932  1.00 75.95 ? 12  ALA D CA  1 
ATOM   6097 C C   . ALA D 4 12  ? 135.306 100.742 92.520  1.00 75.84 ? 12  ALA D C   1 
ATOM   6098 O O   . ALA D 4 12  ? 136.466 101.056 92.255  1.00 77.21 ? 12  ALA D O   1 
ATOM   6099 C CB  . ALA D 4 12  ? 135.023 98.816  94.084  1.00 74.45 ? 12  ALA D CB  1 
ATOM   6100 N N   . ARG D 4 13  ? 134.328 100.736 91.610  1.00 72.58 ? 13  ARG D N   1 
ATOM   6101 C CA  . ARG D 4 13  ? 134.583 101.201 90.250  1.00 71.80 ? 13  ARG D CA  1 
ATOM   6102 C C   . ARG D 4 13  ? 134.947 102.680 90.237  1.00 74.11 ? 13  ARG D C   1 
ATOM   6103 O O   . ARG D 4 13  ? 135.811 103.110 89.464  1.00 71.33 ? 13  ARG D O   1 
ATOM   6104 C CB  . ARG D 4 13  ? 133.360 100.941 89.371  1.00 69.65 ? 13  ARG D CB  1 
ATOM   6105 N N   . LYS D 4 14  ? 134.287 103.479 91.078  1.00 74.03 ? 14  LYS D N   1 
ATOM   6106 C CA  . LYS D 4 14  ? 134.624 104.895 91.173  1.00 73.38 ? 14  LYS D CA  1 
ATOM   6107 C C   . LYS D 4 14  ? 136.016 105.094 91.762  1.00 73.05 ? 14  LYS D C   1 
ATOM   6108 O O   . LYS D 4 14  ? 136.737 106.018 91.369  1.00 73.09 ? 14  LYS D O   1 
ATOM   6109 C CB  . LYS D 4 14  ? 133.579 105.626 92.013  1.00 71.14 ? 14  LYS D CB  1 
ATOM   6110 N N   . LEU D 4 15  ? 136.401 104.246 92.720  1.00 68.50 ? 15  LEU D N   1 
ATOM   6111 C CA  . LEU D 4 15  ? 137.689 104.409 93.390  1.00 69.11 ? 15  LEU D CA  1 
ATOM   6112 C C   . LEU D 4 15  ? 138.852 104.215 92.424  1.00 67.57 ? 15  LEU D C   1 
ATOM   6113 O O   . LEU D 4 15  ? 139.833 104.968 92.468  1.00 66.84 ? 15  LEU D O   1 
ATOM   6114 C CB  . LEU D 4 15  ? 137.788 103.431 94.564  1.00 68.05 ? 15  LEU D CB  1 
ATOM   6115 C CG  . LEU D 4 15  ? 139.136 103.274 95.285  1.00 68.51 ? 15  LEU D CG  1 
ATOM   6116 C CD1 . LEU D 4 15  ? 138.894 103.057 96.773  1.00 66.58 ? 15  LEU D CD1 1 
ATOM   6117 C CD2 . LEU D 4 15  ? 139.978 102.114 94.732  1.00 69.73 ? 15  LEU D CD2 1 
ATOM   6118 N N   . VAL D 4 16  ? 138.773 103.202 91.557  1.00 63.02 ? 16  VAL D N   1 
ATOM   6119 C CA  . VAL D 4 16  ? 139.883 102.926 90.645  1.00 66.75 ? 16  VAL D CA  1 
ATOM   6120 C C   . VAL D 4 16  ? 140.057 104.070 89.652  1.00 66.72 ? 16  VAL D C   1 
ATOM   6121 O O   . VAL D 4 16  ? 141.179 104.381 89.235  1.00 66.70 ? 16  VAL D O   1 
ATOM   6122 C CB  . VAL D 4 16  ? 139.694 101.569 89.930  1.00 65.14 ? 16  VAL D CB  1 
ATOM   6123 C CG1 . VAL D 4 16  ? 138.353 101.471 89.187  1.00 63.55 ? 16  VAL D CG1 1 
ATOM   6124 C CG2 . VAL D 4 16  ? 140.852 101.307 88.975  1.00 64.49 ? 16  VAL D CG2 1 
ATOM   6125 N N   . GLU D 4 17  ? 138.953 104.704 89.247  1.00 64.25 ? 17  GLU D N   1 
ATOM   6126 C CA  . GLU D 4 17  ? 139.050 105.842 88.338  1.00 64.41 ? 17  GLU D CA  1 
ATOM   6127 C C   . GLU D 4 17  ? 139.789 107.005 88.987  1.00 64.96 ? 17  GLU D C   1 
ATOM   6128 O O   . GLU D 4 17  ? 140.648 107.633 88.356  1.00 64.77 ? 17  GLU D O   1 
ATOM   6129 C CB  . GLU D 4 17  ? 137.654 106.275 87.893  1.00 61.63 ? 17  GLU D CB  1 
ATOM   6130 N N   . GLN D 4 18  ? 139.471 107.310 90.247  1.00 59.94 ? 18  GLN D N   1 
ATOM   6131 C CA  . GLN D 4 18  ? 140.199 108.362 90.951  1.00 57.40 ? 18  GLN D CA  1 
ATOM   6132 C C   . GLN D 4 18  ? 141.645 107.959 91.194  1.00 55.46 ? 18  GLN D C   1 
ATOM   6133 O O   . GLN D 4 18  ? 142.558 108.781 91.060  1.00 59.08 ? 18  GLN D O   1 
ATOM   6134 C CB  . GLN D 4 18  ? 139.519 108.704 92.280  1.00 55.21 ? 18  GLN D CB  1 
ATOM   6135 C CG  . GLN D 4 18  ? 138.935 110.105 92.336  1.00 56.09 ? 18  GLN D CG  1 
ATOM   6136 C CD  . GLN D 4 18  ? 140.003 111.180 92.307  1.00 57.24 ? 18  GLN D CD  1 
ATOM   6137 O OE1 . GLN D 4 18  ? 141.044 111.054 92.951  1.00 59.10 ? 18  GLN D OE1 1 
ATOM   6138 N NE2 . GLN D 4 18  ? 139.752 112.245 91.554  1.00 56.55 ? 18  GLN D NE2 1 
ATOM   6139 N N   . LEU D 4 19  ? 141.873 106.697 91.561  1.00 58.57 ? 19  LEU D N   1 
ATOM   6140 C CA  . LEU D 4 19  ? 143.234 106.235 91.806  1.00 58.84 ? 19  LEU D CA  1 
ATOM   6141 C C   . LEU D 4 19  ? 144.054 106.257 90.522  1.00 59.48 ? 19  LEU D C   1 
ATOM   6142 O O   . LEU D 4 19  ? 145.268 106.486 90.556  1.00 62.77 ? 19  LEU D O   1 
ATOM   6143 C CB  . LEU D 4 19  ? 143.200 104.834 92.415  1.00 60.29 ? 19  LEU D CB  1 
ATOM   6144 C CG  . LEU D 4 19  ? 144.447 104.366 93.171  1.00 61.95 ? 19  LEU D CG  1 
ATOM   6145 C CD1 . LEU D 4 19  ? 144.572 105.076 94.509  1.00 61.20 ? 19  LEU D CD1 1 
ATOM   6146 C CD2 . LEU D 4 19  ? 144.404 102.861 93.391  1.00 63.72 ? 19  LEU D CD2 1 
ATOM   6147 N N   . LYS D 4 20  ? 143.408 106.015 89.378  1.00 61.21 ? 20  LYS D N   1 
ATOM   6148 C CA  . LYS D 4 20  ? 144.093 106.155 88.096  1.00 61.62 ? 20  LYS D CA  1 
ATOM   6149 C C   . LYS D 4 20  ? 144.449 107.610 87.813  1.00 62.54 ? 20  LYS D C   1 
ATOM   6150 O O   . LYS D 4 20  ? 145.533 107.901 87.296  1.00 58.92 ? 20  LYS D O   1 
ATOM   6151 C CB  . LYS D 4 20  ? 143.221 105.592 86.975  1.00 59.11 ? 20  LYS D CB  1 
ATOM   6152 N N   . MET D 4 21  ? 143.539 108.537 88.124  1.00 61.58 ? 21  MET D N   1 
ATOM   6153 C CA  . MET D 4 21  ? 143.836 109.952 87.928  1.00 60.45 ? 21  MET D CA  1 
ATOM   6154 C C   . MET D 4 21  ? 144.972 110.403 88.837  1.00 61.38 ? 21  MET D C   1 
ATOM   6155 O O   . MET D 4 21  ? 145.870 111.137 88.407  1.00 59.32 ? 21  MET D O   1 
ATOM   6156 C CB  . MET D 4 21  ? 142.584 110.790 88.182  1.00 55.17 ? 21  MET D CB  1 
ATOM   6157 N N   . GLU D 4 22  ? 144.949 109.974 90.100  1.00 60.75 ? 22  GLU D N   1 
ATOM   6158 C CA  . GLU D 4 22  ? 146.039 110.300 91.012  1.00 59.00 ? 22  GLU D CA  1 
ATOM   6159 C C   . GLU D 4 22  ? 147.308 109.530 90.661  1.00 61.72 ? 22  GLU D C   1 
ATOM   6160 O O   . GLU D 4 22  ? 148.413 109.955 91.018  1.00 66.01 ? 22  GLU D O   1 
ATOM   6161 C CB  . GLU D 4 22  ? 145.620 110.009 92.453  1.00 56.70 ? 22  GLU D CB  1 
ATOM   6162 N N   . ALA D 4 23  ? 147.171 108.383 89.986  1.00 64.00 ? 23  ALA D N   1 
ATOM   6163 C CA  . ALA D 4 23  ? 148.343 107.580 89.648  1.00 63.89 ? 23  ALA D CA  1 
ATOM   6164 C C   . ALA D 4 23  ? 149.280 108.324 88.707  1.00 64.59 ? 23  ALA D C   1 
ATOM   6165 O O   . ALA D 4 23  ? 150.495 108.354 88.935  1.00 66.31 ? 23  ALA D O   1 
ATOM   6166 C CB  . ALA D 4 23  ? 147.917 106.251 89.026  1.00 66.94 ? 23  ALA D CB  1 
ATOM   6167 N N   . ASN D 4 24  ? 148.737 108.937 87.653  1.00 66.11 ? 24  ASN D N   1 
ATOM   6168 C CA  . ASN D 4 24  ? 149.524 109.717 86.703  1.00 68.93 ? 24  ASN D CA  1 
ATOM   6169 C C   . ASN D 4 24  ? 149.392 111.197 87.059  1.00 68.16 ? 24  ASN D C   1 
ATOM   6170 O O   . ASN D 4 24  ? 148.295 111.762 87.044  1.00 67.43 ? 24  ASN D O   1 
ATOM   6171 C CB  . ASN D 4 24  ? 149.136 109.357 85.255  1.00 68.01 ? 24  ASN D CB  1 
ATOM   6172 C CG  . ASN D 4 24  ? 147.776 109.898 84.793  1.00 68.95 ? 24  ASN D CG  1 
ATOM   6173 O OD1 . ASN D 4 24  ? 147.551 111.102 84.690  1.00 68.11 ? 24  ASN D OD1 1 
ATOM   6174 N ND2 . ASN D 4 24  ? 146.853 108.979 84.522  1.00 67.25 ? 24  ASN D ND2 1 
ATOM   6175 N N   . ILE D 4 25  ? 150.498 111.769 87.534  1.00 60.71 ? 25  ILE D N   1 
ATOM   6176 C CA  . ILE D 4 25  ? 150.627 113.191 87.835  1.00 60.70 ? 25  ILE D CA  1 
ATOM   6177 C C   . ILE D 4 25  ? 152.086 113.545 87.593  1.00 64.28 ? 25  ILE D C   1 
ATOM   6178 O O   . ILE D 4 25  ? 152.981 112.726 87.816  1.00 64.93 ? 25  ILE D O   1 
ATOM   6179 C CB  . ILE D 4 25  ? 150.222 113.564 89.292  1.00 60.53 ? 25  ILE D CB  1 
ATOM   6180 C CG1 . ILE D 4 25  ? 148.783 113.162 89.655  1.00 61.97 ? 25  ILE D CG1 1 
ATOM   6181 C CG2 . ILE D 4 25  ? 150.396 115.061 89.539  1.00 61.57 ? 25  ILE D CG2 1 
ATOM   6182 C CD1 . ILE D 4 25  ? 147.697 113.967 88.946  1.00 65.58 ? 25  ILE D CD1 1 
ATOM   6183 N N   . ASP D 4 26  ? 152.329 114.765 87.129  1.00 67.15 ? 26  ASP D N   1 
ATOM   6184 C CA  . ASP D 4 26  ? 153.700 115.241 87.034  1.00 67.56 ? 26  ASP D CA  1 
ATOM   6185 C C   . ASP D 4 26  ? 154.264 115.456 88.432  1.00 68.53 ? 26  ASP D C   1 
ATOM   6186 O O   . ASP D 4 26  ? 153.658 116.138 89.263  1.00 64.92 ? 26  ASP D O   1 
ATOM   6187 C CB  . ASP D 4 26  ? 153.758 116.540 86.231  1.00 65.51 ? 26  ASP D CB  1 
ATOM   6188 N N   . ARG D 4 27  ? 155.436 114.868 88.686  1.00 61.99 ? 27  ARG D N   1 
ATOM   6189 C CA  . ARG D 4 27  ? 156.095 114.918 89.984  1.00 58.71 ? 27  ARG D CA  1 
ATOM   6190 C C   . ARG D 4 27  ? 157.513 115.439 89.812  1.00 58.21 ? 27  ARG D C   1 
ATOM   6191 O O   . ARG D 4 27  ? 158.160 115.200 88.789  1.00 60.85 ? 27  ARG D O   1 
ATOM   6192 C CB  . ARG D 4 27  ? 156.119 113.538 90.656  1.00 55.34 ? 27  ARG D CB  1 
ATOM   6193 C CG  . ARG D 4 27  ? 154.774 113.109 91.218  1.00 58.09 ? 27  ARG D CG  1 
ATOM   6194 C CD  . ARG D 4 27  ? 154.812 111.688 91.752  1.00 58.19 ? 27  ARG D CD  1 
ATOM   6195 N NE  . ARG D 4 27  ? 153.526 111.276 92.307  1.00 60.42 ? 27  ARG D NE  1 
ATOM   6196 C CZ  . ARG D 4 27  ? 152.485 110.845 91.604  1.00 59.74 ? 27  ARG D CZ  1 
ATOM   6197 N NH1 . ARG D 4 27  ? 152.522 110.750 90.283  1.00 56.35 ? 27  ARG D NH1 1 
ATOM   6198 N NH2 . ARG D 4 27  ? 151.372 110.500 92.244  1.00 58.24 ? 27  ARG D NH2 1 
ATOM   6199 N N   . ILE D 4 28  ? 157.985 116.155 90.834  1.00 57.26 ? 28  ILE D N   1 
ATOM   6200 C CA  . ILE D 4 28  ? 159.273 116.838 90.826  1.00 56.02 ? 28  ILE D CA  1 
ATOM   6201 C C   . ILE D 4 28  ? 160.074 116.356 92.028  1.00 58.84 ? 28  ILE D C   1 
ATOM   6202 O O   . ILE D 4 28  ? 159.512 115.899 93.028  1.00 61.79 ? 28  ILE D O   1 
ATOM   6203 C CB  . ILE D 4 28  ? 159.082 118.377 90.844  1.00 55.53 ? 28  ILE D CB  1 
ATOM   6204 C CG1 . ILE D 4 28  ? 160.360 119.134 90.450  1.00 57.79 ? 28  ILE D CG1 1 
ATOM   6205 C CG2 . ILE D 4 28  ? 158.612 118.853 92.216  1.00 51.34 ? 28  ILE D CG2 1 
ATOM   6206 C CD1 . ILE D 4 28  ? 160.800 118.938 89.007  1.00 61.24 ? 28  ILE D CD1 1 
ATOM   6207 N N   . LYS D 4 29  ? 161.397 116.444 91.915  1.00 54.38 ? 29  LYS D N   1 
ATOM   6208 C CA  . LYS D 4 29  ? 162.278 115.956 92.967  1.00 56.75 ? 29  LYS D CA  1 
ATOM   6209 C C   . LYS D 4 29  ? 162.075 116.739 94.261  1.00 57.47 ? 29  LYS D C   1 
ATOM   6210 O O   . LYS D 4 29  ? 161.809 117.947 94.258  1.00 61.15 ? 29  LYS D O   1 
ATOM   6211 C CB  . LYS D 4 29  ? 163.737 116.053 92.521  1.00 56.24 ? 29  LYS D CB  1 
ATOM   6212 N N   . VAL D 4 30  ? 162.205 116.025 95.382  1.00 51.55 ? 30  VAL D N   1 
ATOM   6213 C CA  . VAL D 4 30  ? 162.003 116.644 96.687  1.00 53.76 ? 30  VAL D CA  1 
ATOM   6214 C C   . VAL D 4 30  ? 163.078 117.690 96.943  1.00 53.74 ? 30  VAL D C   1 
ATOM   6215 O O   . VAL D 4 30  ? 162.831 118.697 97.615  1.00 55.46 ? 30  VAL D O   1 
ATOM   6216 C CB  . VAL D 4 30  ? 161.970 115.567 97.790  1.00 53.38 ? 30  VAL D CB  1 
ATOM   6217 C CG1 . VAL D 4 30  ? 162.193 116.174 99.182  1.00 53.73 ? 30  VAL D CG1 1 
ATOM   6218 C CG2 . VAL D 4 30  ? 160.655 114.814 97.747  1.00 52.82 ? 30  VAL D CG2 1 
ATOM   6219 N N   . SER D 4 31  ? 164.293 117.462 96.436  1.00 52.57 ? 31  SER D N   1 
ATOM   6220 C CA  . SER D 4 31  ? 165.342 118.467 96.571  1.00 54.16 ? 31  SER D CA  1 
ATOM   6221 C C   . SER D 4 31  ? 164.962 119.754 95.855  1.00 55.89 ? 31  SER D C   1 
ATOM   6222 O O   . SER D 4 31  ? 165.148 120.849 96.395  1.00 62.94 ? 31  SER D O   1 
ATOM   6223 C CB  . SER D 4 31  ? 166.664 117.933 96.026  1.00 56.60 ? 31  SER D CB  1 
ATOM   6224 O OG  . SER D 4 31  ? 166.634 117.859 94.613  1.00 56.05 ? 31  SER D OG  1 
ATOM   6225 N N   . LYS D 4 32  ? 164.412 119.643 94.643  1.00 44.22 ? 32  LYS D N   1 
ATOM   6226 C CA  . LYS D 4 32  ? 163.980 120.833 93.918  1.00 44.80 ? 32  LYS D CA  1 
ATOM   6227 C C   . LYS D 4 32  ? 162.840 121.536 94.644  1.00 45.81 ? 32  LYS D C   1 
ATOM   6228 O O   . LYS D 4 32  ? 162.813 122.770 94.725  1.00 50.07 ? 32  LYS D O   1 
ATOM   6229 C CB  . LYS D 4 32  ? 163.557 120.456 92.499  1.00 42.25 ? 32  LYS D CB  1 
ATOM   6230 N N   . ALA D 4 33  ? 161.892 120.770 95.184  1.00 43.42 ? 33  ALA D N   1 
ATOM   6231 C CA  . ALA D 4 33  ? 160.762 121.392 95.872  1.00 45.93 ? 33  ALA D CA  1 
ATOM   6232 C C   . ALA D 4 33  ? 161.207 122.087 97.158  1.00 48.18 ? 33  ALA D C   1 
ATOM   6233 O O   . ALA D 4 33  ? 160.762 123.205 97.462  1.00 53.23 ? 33  ALA D O   1 
ATOM   6234 C CB  . ALA D 4 33  ? 159.690 120.344 96.157  1.00 42.74 ? 33  ALA D CB  1 
ATOM   6235 N N   . ALA D 4 34  ? 162.094 121.446 97.922  1.00 44.94 ? 34  ALA D N   1 
ATOM   6236 C CA  . ALA D 4 34  ? 162.644 122.070 99.120  1.00 43.29 ? 34  ALA D CA  1 
ATOM   6237 C C   . ALA D 4 34  ? 163.460 123.307 98.774  1.00 42.68 ? 34  ALA D C   1 
ATOM   6238 O O   . ALA D 4 34  ? 163.432 124.302 99.506  1.00 45.78 ? 34  ALA D O   1 
ATOM   6239 C CB  . ALA D 4 34  ? 163.503 121.063 99.881  1.00 45.35 ? 34  ALA D CB  1 
ATOM   6240 N N   . ALA D 4 35  ? 164.209 123.257 97.671  1.00 37.90 ? 35  ALA D N   1 
ATOM   6241 C CA  . ALA D 4 35  ? 164.958 124.426 97.232  1.00 39.15 ? 35  ALA D CA  1 
ATOM   6242 C C   . ALA D 4 35  ? 164.024 125.572 96.874  1.00 38.82 ? 35  ALA D C   1 
ATOM   6243 O O   . ALA D 4 35  ? 164.326 126.734 97.154  1.00 48.57 ? 35  ALA D O   1 
ATOM   6244 C CB  . ALA D 4 35  ? 165.841 124.065 96.040  1.00 42.03 ? 35  ALA D CB  1 
ATOM   6245 N N   . ASP D 4 36  ? 162.889 125.266 96.244  1.00 33.85 ? 36  ASP D N   1 
ATOM   6246 C CA  . ASP D 4 36  ? 161.914 126.310 95.939  1.00 37.72 ? 36  ASP D CA  1 
ATOM   6247 C C   . ASP D 4 36  ? 161.340 126.924 97.213  1.00 38.58 ? 36  ASP D C   1 
ATOM   6248 O O   . ASP D 4 36  ? 161.170 128.150 97.302  1.00 39.02 ? 36  ASP D O   1 
ATOM   6249 C CB  . ASP D 4 36  ? 160.796 125.740 95.067  1.00 39.58 ? 36  ASP D CB  1 
ATOM   6250 N N   . LEU D 4 37  ? 161.025 126.089 98.208  1.00 35.13 ? 37  LEU D N   1 
ATOM   6251 C CA  . LEU D 4 37  ? 160.511 126.623 99.470  1.00 27.89 ? 37  LEU D CA  1 
ATOM   6252 C C   . LEU D 4 37  ? 161.552 127.496 100.165 1.00 32.21 ? 37  LEU D C   1 
ATOM   6253 O O   . LEU D 4 37  ? 161.224 128.564 100.701 1.00 46.93 ? 37  LEU D O   1 
ATOM   6254 C CB  . LEU D 4 37  ? 160.064 125.490 100.394 1.00 33.15 ? 37  LEU D CB  1 
ATOM   6255 C CG  . LEU D 4 37  ? 158.564 125.180 100.390 1.00 43.12 ? 37  LEU D CG  1 
ATOM   6256 C CD1 . LEU D 4 37  ? 158.048 124.930 98.978  1.00 38.64 ? 37  LEU D CD1 1 
ATOM   6257 C CD2 . LEU D 4 37  ? 158.271 123.995 101.289 1.00 42.10 ? 37  LEU D CD2 1 
ATOM   6258 N N   . MET D 4 38  ? 162.814 127.058 100.166 1.00 35.02 ? 38  MET D N   1 
ATOM   6259 C CA  . MET D 4 38  ? 163.879 127.874 100.741 1.00 37.64 ? 38  MET D CA  1 
ATOM   6260 C C   . MET D 4 38  ? 164.040 129.178 99.975  1.00 38.57 ? 38  MET D C   1 
ATOM   6261 O O   . MET D 4 38  ? 164.296 130.227 100.573 1.00 46.43 ? 38  MET D O   1 
ATOM   6262 C CB  . MET D 4 38  ? 165.201 127.112 100.739 1.00 38.14 ? 38  MET D CB  1 
ATOM   6263 C CG  . MET D 4 38  ? 165.347 126.083 101.850 1.00 42.97 ? 38  MET D CG  1 
ATOM   6264 S SD  . MET D 4 38  ? 167.039 125.509 102.129 1.00 58.62 ? 38  MET D SD  1 
ATOM   6265 C CE  . MET D 4 38  ? 167.760 125.585 100.491 1.00 43.86 ? 38  MET D CE  1 
ATOM   6266 N N   . ALA D 4 39  ? 163.922 129.126 98.645  1.00 33.11 ? 39  ALA D N   1 
ATOM   6267 C CA  . ALA D 4 39  ? 164.033 130.338 97.845  1.00 32.66 ? 39  ALA D CA  1 
ATOM   6268 C C   . ALA D 4 39  ? 162.957 131.338 98.232  1.00 35.87 ? 39  ALA D C   1 
ATOM   6269 O O   . ALA D 4 39  ? 163.249 132.521 98.435  1.00 42.86 ? 39  ALA D O   1 
ATOM   6270 C CB  . ALA D 4 39  ? 163.937 130.000 96.359  1.00 37.43 ? 39  ALA D CB  1 
ATOM   6271 N N   . TYR D 4 40  ? 161.718 130.867 98.399  1.00 37.29 ? 40  TYR D N   1 
ATOM   6272 C CA  . TYR D 4 40  ? 160.647 131.765 98.822  1.00 35.25 ? 40  TYR D CA  1 
ATOM   6273 C C   . TYR D 4 40  ? 160.921 132.346 100.207 1.00 30.89 ? 40  TYR D C   1 
ATOM   6274 O O   . TYR D 4 40  ? 160.791 133.561 100.414 1.00 34.04 ? 40  TYR D O   1 
ATOM   6275 C CB  . TYR D 4 40  ? 159.302 131.033 98.804  1.00 31.01 ? 40  TYR D CB  1 
ATOM   6276 C CG  . TYR D 4 40  ? 158.122 131.946 99.048  1.00 34.78 ? 40  TYR D CG  1 
ATOM   6277 C CD1 . TYR D 4 40  ? 157.502 132.605 97.996  1.00 39.25 ? 40  TYR D CD1 1 
ATOM   6278 C CD2 . TYR D 4 40  ? 157.625 132.150 100.327 1.00 31.37 ? 40  TYR D CD2 1 
ATOM   6279 C CE1 . TYR D 4 40  ? 156.428 133.443 98.214  1.00 30.36 ? 40  TYR D CE1 1 
ATOM   6280 C CE2 . TYR D 4 40  ? 156.558 132.986 100.552 1.00 31.47 ? 40  TYR D CE2 1 
ATOM   6281 C CZ  . TYR D 4 40  ? 155.960 133.628 99.494  1.00 31.18 ? 40  TYR D CZ  1 
ATOM   6282 O OH  . TYR D 4 40  ? 154.889 134.462 99.716  1.00 33.83 ? 40  TYR D OH  1 
ATOM   6283 N N   . CYS D 4 41  ? 161.316 131.500 101.164 1.00 29.35 ? 41  CYS D N   1 
ATOM   6284 C CA  . CYS D 4 41  ? 161.469 131.975 102.538 1.00 31.72 ? 41  CYS D CA  1 
ATOM   6285 C C   . CYS D 4 41  ? 162.631 132.955 102.683 1.00 42.59 ? 41  CYS D C   1 
ATOM   6286 O O   . CYS D 4 41  ? 162.516 133.950 103.407 1.00 46.23 ? 41  CYS D O   1 
ATOM   6287 C CB  . CYS D 4 41  ? 161.634 130.792 103.488 1.00 30.65 ? 41  CYS D CB  1 
ATOM   6288 S SG  . CYS D 4 41  ? 160.097 129.909 103.787 1.00 31.71 ? 41  CYS D SG  1 
ATOM   6289 N N   . GLU D 4 42  ? 163.765 132.691 102.027 1.00 42.04 ? 42  GLU D N   1 
ATOM   6290 C CA  . GLU D 4 42  ? 164.870 133.649 102.063 1.00 37.58 ? 42  GLU D CA  1 
ATOM   6291 C C   . GLU D 4 42  ? 164.557 134.911 101.267 1.00 37.39 ? 42  GLU D C   1 
ATOM   6292 O O   . GLU D 4 42  ? 165.026 135.999 101.620 1.00 43.27 ? 42  GLU D O   1 
ATOM   6293 C CB  . GLU D 4 42  ? 166.165 133.003 101.568 1.00 36.42 ? 42  GLU D CB  1 
ATOM   6294 C CG  . GLU D 4 42  ? 167.020 132.324 102.653 1.00 43.08 ? 42  GLU D CG  1 
ATOM   6295 C CD  . GLU D 4 42  ? 166.376 131.122 103.314 1.00 46.94 ? 42  GLU D CD  1 
ATOM   6296 O OE1 . GLU D 4 42  ? 165.236 130.773 102.967 1.00 47.22 ? 42  GLU D OE1 1 
ATOM   6297 O OE2 . GLU D 4 42  ? 167.037 130.515 104.182 1.00 48.43 ? 42  GLU D OE2 1 
ATOM   6298 N N   . ALA D 4 43  ? 163.789 134.796 100.179 1.00 35.10 ? 43  ALA D N   1 
ATOM   6299 C CA  . ALA D 4 43  ? 163.434 135.986 99.415  1.00 36.88 ? 43  ALA D CA  1 
ATOM   6300 C C   . ALA D 4 43  ? 162.551 136.925 100.228 1.00 39.51 ? 43  ALA D C   1 
ATOM   6301 O O   . ALA D 4 43  ? 162.751 138.145 100.208 1.00 42.17 ? 43  ALA D O   1 
ATOM   6302 C CB  . ALA D 4 43  ? 162.736 135.584 98.118  1.00 41.34 ? 43  ALA D CB  1 
ATOM   6303 N N   . HIS D 4 44  ? 161.577 136.376 100.955 1.00 41.52 ? 44  HIS D N   1 
ATOM   6304 C CA  . HIS D 4 44  ? 160.603 137.173 101.696 1.00 38.87 ? 44  HIS D CA  1 
ATOM   6305 C C   . HIS D 4 44  ? 160.937 137.325 103.178 1.00 40.38 ? 44  HIS D C   1 
ATOM   6306 O O   . HIS D 4 44  ? 160.067 137.737 103.950 1.00 46.16 ? 44  HIS D O   1 
ATOM   6307 C CB  . HIS D 4 44  ? 159.210 136.558 101.533 1.00 40.09 ? 44  HIS D CB  1 
ATOM   6308 C CG  . HIS D 4 44  ? 158.675 136.655 100.140 1.00 43.12 ? 44  HIS D CG  1 
ATOM   6309 N ND1 . HIS D 4 44  ? 159.224 135.966 99.081  1.00 38.29 ? 44  HIS D ND1 1 
ATOM   6310 C CD2 . HIS D 4 44  ? 157.644 137.369 99.631  1.00 45.61 ? 44  HIS D CD2 1 
ATOM   6311 C CE1 . HIS D 4 44  ? 158.552 136.249 97.980  1.00 37.65 ? 44  HIS D CE1 1 
ATOM   6312 N NE2 . HIS D 4 44  ? 157.588 137.098 98.286  1.00 45.89 ? 44  HIS D NE2 1 
ATOM   6313 N N   . ALA D 4 45  ? 162.169 137.016 103.593 1.00 42.17 ? 45  ALA D N   1 
ATOM   6314 C CA  . ALA D 4 45  ? 162.514 137.076 105.012 1.00 42.57 ? 45  ALA D CA  1 
ATOM   6315 C C   . ALA D 4 45  ? 162.433 138.499 105.556 1.00 44.89 ? 45  ALA D C   1 
ATOM   6316 O O   . ALA D 4 45  ? 161.941 138.718 106.668 1.00 39.20 ? 45  ALA D O   1 
ATOM   6317 C CB  . ALA D 4 45  ? 163.913 136.505 105.234 1.00 42.16 ? 45  ALA D CB  1 
ATOM   6318 N N   . LYS D 4 46  ? 162.921 139.478 104.790 1.00 53.49 ? 46  LYS D N   1 
ATOM   6319 C CA  . LYS D 4 46  ? 162.926 140.858 105.266 1.00 53.49 ? 46  LYS D CA  1 
ATOM   6320 C C   . LYS D 4 46  ? 161.511 141.403 105.414 1.00 53.32 ? 46  LYS D C   1 
ATOM   6321 O O   . LYS D 4 46  ? 161.234 142.192 106.325 1.00 49.95 ? 46  LYS D O   1 
ATOM   6322 C CB  . LYS D 4 46  ? 163.738 141.734 104.312 1.00 46.38 ? 46  LYS D CB  1 
ATOM   6323 N N   . GLU D 4 47  ? 160.603 141.002 104.522 1.00 49.33 ? 47  GLU D N   1 
ATOM   6324 C CA  . GLU D 4 47  ? 159.241 141.527 104.554 1.00 40.60 ? 47  GLU D CA  1 
ATOM   6325 C C   . GLU D 4 47  ? 158.493 141.104 105.814 1.00 42.33 ? 47  GLU D C   1 
ATOM   6326 O O   . GLU D 4 47  ? 157.563 141.792 106.244 1.00 51.32 ? 47  GLU D O   1 
ATOM   6327 C CB  . GLU D 4 47  ? 158.480 141.068 103.312 1.00 42.23 ? 47  GLU D CB  1 
ATOM   6328 C CG  . GLU D 4 47  ? 159.003 141.662 102.013 1.00 48.13 ? 47  GLU D CG  1 
ATOM   6329 C CD  . GLU D 4 47  ? 157.970 141.655 100.904 1.00 53.90 ? 47  GLU D CD  1 
ATOM   6330 O OE1 . GLU D 4 47  ? 156.840 142.136 101.132 1.00 54.07 ? 47  GLU D OE1 1 
ATOM   6331 O OE2 . GLU D 4 47  ? 158.291 141.169 99.799  1.00 53.65 ? 47  GLU D OE2 1 
ATOM   6332 N N   . ASP D 4 48  ? 158.885 139.987 106.423 1.00 41.92 ? 48  ASP D N   1 
ATOM   6333 C CA  . ASP D 4 48  ? 158.095 139.379 107.491 1.00 40.16 ? 48  ASP D CA  1 
ATOM   6334 C C   . ASP D 4 48  ? 158.252 140.150 108.801 1.00 44.23 ? 48  ASP D C   1 
ATOM   6335 O O   . ASP D 4 48  ? 159.376 140.266 109.300 1.00 49.21 ? 48  ASP D O   1 
ATOM   6336 C CB  . ASP D 4 48  ? 158.536 137.940 107.694 1.00 38.43 ? 48  ASP D CB  1 
ATOM   6337 C CG  . ASP D 4 48  ? 157.542 137.134 108.493 1.00 45.39 ? 48  ASP D CG  1 
ATOM   6338 O OD1 . ASP D 4 48  ? 156.507 137.689 108.917 1.00 48.54 ? 48  ASP D OD1 1 
ATOM   6339 O OD2 . ASP D 4 48  ? 157.790 135.927 108.700 1.00 41.98 ? 48  ASP D OD2 1 
ATOM   6340 N N   . PRO D 4 49  ? 157.171 140.676 109.404 1.00 37.96 ? 49  PRO D N   1 
ATOM   6341 C CA  . PRO D 4 49  ? 157.342 141.328 110.715 1.00 32.13 ? 49  PRO D CA  1 
ATOM   6342 C C   . PRO D 4 49  ? 157.563 140.366 111.871 1.00 31.72 ? 49  PRO D C   1 
ATOM   6343 O O   . PRO D 4 49  ? 158.312 140.692 112.798 1.00 40.90 ? 49  PRO D O   1 
ATOM   6344 C CB  . PRO D 4 49  ? 156.027 142.101 110.884 1.00 32.47 ? 49  PRO D CB  1 
ATOM   6345 C CG  . PRO D 4 49  ? 155.554 142.320 109.511 1.00 34.70 ? 49  PRO D CG  1 
ATOM   6346 C CD  . PRO D 4 49  ? 155.847 141.017 108.852 1.00 38.16 ? 49  PRO D CD  1 
ATOM   6347 N N   . LEU D 4 50  ? 156.903 139.207 111.874 1.00 39.83 ? 50  LEU D N   1 
ATOM   6348 C CA  . LEU D 4 50  ? 156.991 138.320 113.031 1.00 39.00 ? 50  LEU D CA  1 
ATOM   6349 C C   . LEU D 4 50  ? 158.380 137.709 113.161 1.00 36.94 ? 50  LEU D C   1 
ATOM   6350 O O   . LEU D 4 50  ? 158.868 137.491 114.275 1.00 36.11 ? 50  LEU D O   1 
ATOM   6351 C CB  . LEU D 4 50  ? 155.937 137.217 112.936 1.00 29.26 ? 50  LEU D CB  1 
ATOM   6352 C CG  . LEU D 4 50  ? 154.475 137.666 112.944 1.00 28.42 ? 50  LEU D CG  1 
ATOM   6353 C CD1 . LEU D 4 50  ? 153.560 136.488 112.665 1.00 36.65 ? 50  LEU D CD1 1 
ATOM   6354 C CD2 . LEU D 4 50  ? 154.082 138.355 114.241 1.00 26.92 ? 50  LEU D CD2 1 
ATOM   6355 N N   . LEU D 4 51  ? 159.023 137.404 112.032 1.00 36.13 ? 51  LEU D N   1 
ATOM   6356 C CA  . LEU D 4 51  ? 160.342 136.782 112.078 1.00 36.90 ? 51  LEU D CA  1 
ATOM   6357 C C   . LEU D 4 51  ? 161.374 137.724 112.684 1.00 42.48 ? 51  LEU D C   1 
ATOM   6358 O O   . LEU D 4 51  ? 162.181 137.311 113.526 1.00 48.44 ? 51  LEU D O   1 
ATOM   6359 C CB  . LEU D 4 51  ? 160.754 136.353 110.669 1.00 40.00 ? 51  LEU D CB  1 
ATOM   6360 C CG  . LEU D 4 51  ? 162.086 135.623 110.478 1.00 37.53 ? 51  LEU D CG  1 
ATOM   6361 C CD1 . LEU D 4 51  ? 161.962 134.186 110.922 1.00 37.58 ? 51  LEU D CD1 1 
ATOM   6362 C CD2 . LEU D 4 51  ? 162.516 135.687 109.026 1.00 42.52 ? 51  LEU D CD2 1 
ATOM   6363 N N   . THR D 4 52  ? 161.359 138.991 112.270 1.00 46.92 ? 52  THR D N   1 
ATOM   6364 C CA  . THR D 4 52  ? 162.274 140.027 112.723 1.00 48.21 ? 52  THR D CA  1 
ATOM   6365 C C   . THR D 4 52  ? 161.460 141.177 113.310 1.00 47.99 ? 52  THR D C   1 
ATOM   6366 O O   . THR D 4 52  ? 160.708 141.813 112.558 1.00 44.73 ? 52  THR D O   1 
ATOM   6367 C CB  . THR D 4 52  ? 163.126 140.544 111.558 1.00 50.76 ? 52  THR D CB  1 
ATOM   6368 O OG1 . THR D 4 52  ? 162.288 141.231 110.621 1.00 49.77 ? 52  THR D OG1 1 
ATOM   6369 C CG2 . THR D 4 52  ? 163.830 139.392 110.854 1.00 46.40 ? 52  THR D CG2 1 
ATOM   6370 N N   . PRO D 4 53  ? 161.578 141.497 114.612 1.00 57.46 ? 53  PRO D N   1 
ATOM   6371 C CA  . PRO D 4 53  ? 160.572 142.372 115.239 1.00 56.61 ? 53  PRO D CA  1 
ATOM   6372 C C   . PRO D 4 53  ? 160.568 143.781 114.658 1.00 57.98 ? 53  PRO D C   1 
ATOM   6373 O O   . PRO D 4 53  ? 161.603 144.444 114.562 1.00 60.21 ? 53  PRO D O   1 
ATOM   6374 C CB  . PRO D 4 53  ? 160.973 142.384 116.720 1.00 54.69 ? 53  PRO D CB  1 
ATOM   6375 C CG  . PRO D 4 53  ? 162.385 142.000 116.753 1.00 57.61 ? 53  PRO D CG  1 
ATOM   6376 C CD  . PRO D 4 53  ? 162.641 141.131 115.570 1.00 58.94 ? 53  PRO D CD  1 
ATOM   6377 N N   . VAL D 4 54  ? 159.376 144.226 114.272 1.00 55.79 ? 54  VAL D N   1 
ATOM   6378 C CA  . VAL D 4 54  ? 159.160 145.507 113.604 1.00 53.82 ? 54  VAL D CA  1 
ATOM   6379 C C   . VAL D 4 54  ? 159.425 146.606 114.631 1.00 61.89 ? 54  VAL D C   1 
ATOM   6380 O O   . VAL D 4 54  ? 159.115 146.404 115.815 1.00 61.09 ? 54  VAL D O   1 
ATOM   6381 C CB  . VAL D 4 54  ? 157.734 145.552 113.014 1.00 52.57 ? 54  VAL D CB  1 
ATOM   6382 C CG1 . VAL D 4 54  ? 156.665 145.764 114.111 1.00 54.66 ? 54  VAL D CG1 1 
ATOM   6383 C CG2 . VAL D 4 54  ? 157.602 146.575 111.887 1.00 52.32 ? 54  VAL D CG2 1 
ATOM   6384 N N   . PRO D 4 55  ? 160.004 147.760 114.274 1.00 70.89 ? 55  PRO D N   1 
ATOM   6385 C CA  . PRO D 4 55  ? 160.268 148.768 115.305 1.00 65.43 ? 55  PRO D CA  1 
ATOM   6386 C C   . PRO D 4 55  ? 158.985 149.407 115.811 1.00 63.68 ? 55  PRO D C   1 
ATOM   6387 O O   . PRO D 4 55  ? 157.952 149.399 115.138 1.00 65.87 ? 55  PRO D O   1 
ATOM   6388 C CB  . PRO D 4 55  ? 161.171 149.780 114.593 1.00 65.91 ? 55  PRO D CB  1 
ATOM   6389 C CG  . PRO D 4 55  ? 160.800 149.681 113.183 1.00 64.25 ? 55  PRO D CG  1 
ATOM   6390 C CD  . PRO D 4 55  ? 160.487 148.227 112.955 1.00 65.78 ? 55  PRO D CD  1 
ATOM   6391 N N   . ALA D 4 56  ? 159.070 149.960 117.026 1.00 61.16 ? 56  ALA D N   1 
ATOM   6392 C CA  . ALA D 4 56  ? 157.874 150.366 117.761 1.00 61.87 ? 56  ALA D CA  1 
ATOM   6393 C C   . ALA D 4 56  ? 157.105 151.467 117.040 1.00 63.47 ? 56  ALA D C   1 
ATOM   6394 O O   . ALA D 4 56  ? 155.873 151.528 117.129 1.00 61.66 ? 56  ALA D O   1 
ATOM   6395 C CB  . ALA D 4 56  ? 158.255 150.822 119.168 1.00 58.99 ? 56  ALA D CB  1 
ATOM   6396 N N   . SER D 4 57  ? 157.807 152.358 116.338 1.00 66.64 ? 57  SER D N   1 
ATOM   6397 C CA  . SER D 4 57  ? 157.109 153.371 115.553 1.00 67.89 ? 57  SER D CA  1 
ATOM   6398 C C   . SER D 4 57  ? 156.302 152.731 114.432 1.00 65.28 ? 57  SER D C   1 
ATOM   6399 O O   . SER D 4 57  ? 155.150 153.110 114.188 1.00 65.99 ? 57  SER D O   1 
ATOM   6400 C CB  . SER D 4 57  ? 158.106 154.379 114.984 1.00 67.55 ? 57  SER D CB  1 
ATOM   6401 O OG  . SER D 4 57  ? 159.106 153.730 114.219 1.00 66.90 ? 57  SER D OG  1 
ATOM   6402 N N   . GLU D 4 58  ? 156.891 151.755 113.740 1.00 58.58 ? 58  GLU D N   1 
ATOM   6403 C CA  . GLU D 4 58  ? 156.181 151.073 112.663 1.00 61.62 ? 58  GLU D CA  1 
ATOM   6404 C C   . GLU D 4 58  ? 155.069 150.176 113.199 1.00 60.19 ? 58  GLU D C   1 
ATOM   6405 O O   . GLU D 4 58  ? 154.119 149.860 112.475 1.00 59.73 ? 58  GLU D O   1 
ATOM   6406 C CB  . GLU D 4 58  ? 157.171 150.258 111.835 1.00 62.81 ? 58  GLU D CB  1 
ATOM   6407 C CG  . GLU D 4 58  ? 158.043 151.091 110.919 1.00 65.05 ? 58  GLU D CG  1 
ATOM   6408 C CD  . GLU D 4 58  ? 158.939 150.245 110.035 1.00 67.43 ? 58  GLU D CD  1 
ATOM   6409 O OE1 . GLU D 4 58  ? 158.420 149.345 109.342 1.00 64.96 ? 58  GLU D OE1 1 
ATOM   6410 O OE2 . GLU D 4 58  ? 160.165 150.481 110.037 1.00 66.83 ? 58  GLU D OE2 1 
ATOM   6411 N N   . ASN D 4 59  ? 155.175 149.743 114.452 1.00 50.93 ? 59  ASN D N   1 
ATOM   6412 C CA  . ASN D 4 59  ? 154.208 148.807 115.004 1.00 47.71 ? 59  ASN D CA  1 
ATOM   6413 C C   . ASN D 4 59  ? 152.855 149.506 115.167 1.00 47.20 ? 59  ASN D C   1 
ATOM   6414 O O   . ASN D 4 59  ? 152.777 150.524 115.869 1.00 46.04 ? 59  ASN D O   1 
ATOM   6415 C CB  . ASN D 4 59  ? 154.709 148.293 116.355 1.00 48.60 ? 59  ASN D CB  1 
ATOM   6416 C CG  . ASN D 4 59  ? 153.903 147.117 116.889 1.00 52.46 ? 59  ASN D CG  1 
ATOM   6417 O OD1 . ASN D 4 59  ? 152.703 146.989 116.645 1.00 50.22 ? 59  ASN D OD1 1 
ATOM   6418 N ND2 . ASN D 4 59  ? 154.575 146.245 117.629 1.00 48.19 ? 59  ASN D ND2 1 
ATOM   6419 N N   . PRO D 4 60  ? 151.771 149.010 114.548 1.00 42.50 ? 60  PRO D N   1 
ATOM   6420 C CA  . PRO D 4 60  ? 150.455 149.590 114.864 1.00 34.72 ? 60  PRO D CA  1 
ATOM   6421 C C   . PRO D 4 60  ? 149.981 149.250 116.264 1.00 37.06 ? 60  PRO D C   1 
ATOM   6422 O O   . PRO D 4 60  ? 149.234 150.031 116.867 1.00 38.85 ? 60  PRO D O   1 
ATOM   6423 C CB  . PRO D 4 60  ? 149.537 148.987 113.790 1.00 32.47 ? 60  PRO D CB  1 
ATOM   6424 C CG  . PRO D 4 60  ? 150.446 148.484 112.733 1.00 36.73 ? 60  PRO D CG  1 
ATOM   6425 C CD  . PRO D 4 60  ? 151.643 148.014 113.471 1.00 41.88 ? 60  PRO D CD  1 
ATOM   6426 N N   . PHE D 4 61  ? 150.384 148.094 116.788 1.00 33.87 ? 61  PHE D N   1 
ATOM   6427 C CA  . PHE D 4 61  ? 150.051 147.673 118.147 1.00 32.44 ? 61  PHE D CA  1 
ATOM   6428 C C   . PHE D 4 61  ? 151.197 148.012 119.094 1.00 34.41 ? 61  PHE D C   1 
ATOM   6429 O O   . PHE D 4 61  ? 151.133 148.987 119.842 1.00 26.06 ? 61  PHE D O   1 
ATOM   6430 C CB  . PHE D 4 61  ? 149.750 146.167 118.212 1.00 34.65 ? 61  PHE D CB  1 
ATOM   6431 C CG  . PHE D 4 61  ? 148.865 145.658 117.101 1.00 34.18 ? 61  PHE D CG  1 
ATOM   6432 C CD1 . PHE D 4 61  ? 149.399 145.256 115.889 1.00 38.76 ? 61  PHE D CD1 1 
ATOM   6433 C CD2 . PHE D 4 61  ? 147.495 145.575 117.279 1.00 28.51 ? 61  PHE D CD2 1 
ATOM   6434 C CE1 . PHE D 4 61  ? 148.584 144.789 114.878 1.00 33.61 ? 61  PHE D CE1 1 
ATOM   6435 C CE2 . PHE D 4 61  ? 146.678 145.110 116.271 1.00 29.14 ? 61  PHE D CE2 1 
ATOM   6436 C CZ  . PHE D 4 61  ? 147.224 144.715 115.071 1.00 27.37 ? 61  PHE D CZ  1 
ATOM   6437 N N   . VAL E 5 2   ? 114.675 154.610 103.632 1.00 32.62 ? 2   VAL E N   1 
ATOM   6438 C CA  . VAL E 5 2   ? 115.190 155.489 104.674 1.00 29.08 ? 2   VAL E CA  1 
ATOM   6439 C C   . VAL E 5 2   ? 114.612 156.875 104.451 1.00 30.07 ? 2   VAL E C   1 
ATOM   6440 O O   . VAL E 5 2   ? 114.688 157.412 103.349 1.00 32.76 ? 2   VAL E O   1 
ATOM   6441 C CB  . VAL E 5 2   ? 116.738 155.517 104.693 1.00 29.72 ? 2   VAL E CB  1 
ATOM   6442 C CG1 . VAL E 5 2   ? 117.277 154.178 105.145 1.00 27.56 ? 2   VAL E CG1 1 
ATOM   6443 C CG2 . VAL E 5 2   ? 117.327 155.900 103.331 1.00 35.43 ? 2   VAL E CG2 1 
ATOM   6444 N N   . GLN E 5 3   ? 114.005 157.442 105.491 1.00 28.45 ? 3   GLN E N   1 
ATOM   6445 C CA  . GLN E 5 3   ? 113.363 158.743 105.400 1.00 24.79 ? 3   GLN E CA  1 
ATOM   6446 C C   . GLN E 5 3   ? 113.473 159.464 106.735 1.00 33.79 ? 3   GLN E C   1 
ATOM   6447 O O   . GLN E 5 3   ? 113.377 158.843 107.797 1.00 33.07 ? 3   GLN E O   1 
ATOM   6448 C CB  . GLN E 5 3   ? 111.889 158.594 104.995 1.00 26.04 ? 3   GLN E CB  1 
ATOM   6449 C CG  . GLN E 5 3   ? 111.178 159.914 104.657 1.00 36.64 ? 3   GLN E CG  1 
ATOM   6450 C CD  . GLN E 5 3   ? 109.667 159.783 104.474 1.00 42.36 ? 3   GLN E CD  1 
ATOM   6451 O OE1 . GLN E 5 3   ? 109.106 160.339 103.530 1.00 39.96 ? 3   GLN E OE1 1 
ATOM   6452 N NE2 . GLN E 5 3   ? 108.999 159.093 105.395 1.00 38.32 ? 3   GLN E NE2 1 
ATOM   6453 N N   . LEU E 5 4   ? 113.694 160.775 106.666 1.00 38.81 ? 4   LEU E N   1 
ATOM   6454 C CA  . LEU E 5 4   ? 113.573 161.681 107.800 1.00 30.52 ? 4   LEU E CA  1 
ATOM   6455 C C   . LEU E 5 4   ? 112.663 162.825 107.381 1.00 28.30 ? 4   LEU E C   1 
ATOM   6456 O O   . LEU E 5 4   ? 112.955 163.514 106.400 1.00 40.80 ? 4   LEU E O   1 
ATOM   6457 C CB  . LEU E 5 4   ? 114.937 162.227 108.234 1.00 27.75 ? 4   LEU E CB  1 
ATOM   6458 C CG  . LEU E 5 4   ? 115.873 161.259 108.963 1.00 22.31 ? 4   LEU E CG  1 
ATOM   6459 C CD1 . LEU E 5 4   ? 117.323 161.696 108.862 1.00 19.18 ? 4   LEU E CD1 1 
ATOM   6460 C CD2 . LEU E 5 4   ? 115.471 161.136 110.413 1.00 32.90 ? 4   LEU E CD2 1 
ATOM   6461 N N   . VAL E 5 5   ? 111.573 163.025 108.119 1.00 22.99 ? 5   VAL E N   1 
ATOM   6462 C CA  . VAL E 5 5   ? 110.580 164.054 107.821 1.00 35.44 ? 5   VAL E CA  1 
ATOM   6463 C C   . VAL E 5 5   ? 110.507 165.001 109.007 1.00 41.72 ? 5   VAL E C   1 
ATOM   6464 O O   . VAL E 5 5   ? 110.213 164.572 110.127 1.00 50.81 ? 5   VAL E O   1 
ATOM   6465 C CB  . VAL E 5 5   ? 109.194 163.449 107.531 1.00 39.13 ? 5   VAL E CB  1 
ATOM   6466 C CG1 . VAL E 5 5   ? 108.188 164.552 107.197 1.00 35.26 ? 5   VAL E CG1 1 
ATOM   6467 C CG2 . VAL E 5 5   ? 109.284 162.429 106.406 1.00 39.16 ? 5   VAL E CG2 1 
ATOM   6468 N N   . GLU E 5 6   ? 110.723 166.287 108.749 1.00 33.44 ? 6   GLU E N   1 
ATOM   6469 C CA  . GLU E 5 6   ? 110.746 167.319 109.776 1.00 37.27 ? 6   GLU E CA  1 
ATOM   6470 C C   . GLU E 5 6   ? 109.386 167.995 109.846 1.00 44.26 ? 6   GLU E C   1 
ATOM   6471 O O   . GLU E 5 6   ? 108.776 168.279 108.811 1.00 37.76 ? 6   GLU E O   1 
ATOM   6472 C CB  . GLU E 5 6   ? 111.842 168.349 109.487 1.00 40.76 ? 6   GLU E CB  1 
ATOM   6473 C CG  . GLU E 5 6   ? 113.261 167.848 109.753 1.00 36.66 ? 6   GLU E CG  1 
ATOM   6474 C CD  . GLU E 5 6   ? 114.074 167.531 108.512 1.00 38.44 ? 6   GLU E CD  1 
ATOM   6475 O OE1 . GLU E 5 6   ? 113.536 167.507 107.389 1.00 47.10 ? 6   GLU E OE1 1 
ATOM   6476 O OE2 . GLU E 5 6   ? 115.281 167.291 108.670 1.00 33.26 ? 6   GLU E OE2 1 
ATOM   6477 N N   . SER E 5 7   ? 108.919 168.242 111.070 1.00 54.42 ? 7   SER E N   1 
ATOM   6478 C CA  . SER E 5 7   ? 107.634 168.874 111.333 1.00 52.17 ? 7   SER E CA  1 
ATOM   6479 C C   . SER E 5 7   ? 107.833 170.010 112.325 1.00 49.04 ? 7   SER E C   1 
ATOM   6480 O O   . SER E 5 7   ? 108.848 170.080 113.022 1.00 47.82 ? 7   SER E O   1 
ATOM   6481 C CB  . SER E 5 7   ? 106.612 167.868 111.879 1.00 51.69 ? 7   SER E CB  1 
ATOM   6482 O OG  . SER E 5 7   ? 105.296 168.382 111.789 1.00 52.41 ? 7   SER E OG  1 
ATOM   6483 N N   . GLY E 5 8   ? 106.848 170.897 112.380 1.00 53.88 ? 8   GLY E N   1 
ATOM   6484 C CA  . GLY E 5 8   ? 106.957 172.139 113.114 1.00 52.78 ? 8   GLY E CA  1 
ATOM   6485 C C   . GLY E 5 8   ? 107.508 173.252 112.239 1.00 55.61 ? 8   GLY E C   1 
ATOM   6486 O O   . GLY E 5 8   ? 108.091 173.020 111.179 1.00 61.76 ? 8   GLY E O   1 
ATOM   6487 N N   . GLY E 5 9   ? 107.299 174.480 112.682 1.00 49.41 ? 9   GLY E N   1 
ATOM   6488 C CA  . GLY E 5 9   ? 107.768 175.644 111.955 1.00 50.54 ? 9   GLY E CA  1 
ATOM   6489 C C   . GLY E 5 9   ? 106.751 176.763 112.028 1.00 54.36 ? 9   GLY E C   1 
ATOM   6490 O O   . GLY E 5 9   ? 105.840 176.757 112.849 1.00 57.54 ? 9   GLY E O   1 
ATOM   6491 N N   . GLY E 5 10  ? 106.926 177.727 111.126 1.00 54.65 ? 10  GLY E N   1 
ATOM   6492 C CA  . GLY E 5 10  ? 106.063 178.889 111.065 1.00 53.36 ? 10  GLY E CA  1 
ATOM   6493 C C   . GLY E 5 10  ? 106.597 180.053 111.872 1.00 56.09 ? 10  GLY E C   1 
ATOM   6494 O O   . GLY E 5 10  ? 107.653 179.996 112.508 1.00 55.90 ? 10  GLY E O   1 
ATOM   6495 N N   . LEU E 5 11  ? 105.836 181.143 111.837 1.00 60.26 ? 11  LEU E N   1 
ATOM   6496 C CA  . LEU E 5 11  ? 106.274 182.380 112.469 1.00 60.35 ? 11  LEU E CA  1 
ATOM   6497 C C   . LEU E 5 11  ? 106.221 182.270 113.986 1.00 57.66 ? 11  LEU E C   1 
ATOM   6498 O O   . LEU E 5 11  ? 105.243 181.783 114.559 1.00 59.36 ? 11  LEU E O   1 
ATOM   6499 C CB  . LEU E 5 11  ? 105.419 183.560 111.991 1.00 58.16 ? 11  LEU E CB  1 
ATOM   6500 C CG  . LEU E 5 11  ? 104.010 183.807 112.553 1.00 61.49 ? 11  LEU E CG  1 
ATOM   6501 C CD1 . LEU E 5 11  ? 103.480 185.132 112.031 1.00 59.50 ? 11  LEU E CD1 1 
ATOM   6502 C CD2 . LEU E 5 11  ? 103.050 182.679 112.216 1.00 58.41 ? 11  LEU E CD2 1 
ATOM   6503 N N   . VAL E 5 12  ? 107.293 182.725 114.631 1.00 51.11 ? 12  VAL E N   1 
ATOM   6504 C CA  . VAL E 5 12  ? 107.361 182.889 116.078 1.00 52.98 ? 12  VAL E CA  1 
ATOM   6505 C C   . VAL E 5 12  ? 107.779 184.324 116.350 1.00 57.20 ? 12  VAL E C   1 
ATOM   6506 O O   . VAL E 5 12  ? 108.772 184.801 115.789 1.00 60.05 ? 12  VAL E O   1 
ATOM   6507 C CB  . VAL E 5 12  ? 108.352 181.906 116.728 1.00 50.82 ? 12  VAL E CB  1 
ATOM   6508 C CG1 . VAL E 5 12  ? 108.512 182.219 118.211 1.00 53.00 ? 12  VAL E CG1 1 
ATOM   6509 C CG2 . VAL E 5 12  ? 107.905 180.468 116.534 1.00 56.85 ? 12  VAL E CG2 1 
ATOM   6510 N N   . GLN E 5 13  ? 107.026 185.013 117.198 1.00 60.31 ? 13  GLN E N   1 
ATOM   6511 C CA  . GLN E 5 13  ? 107.412 186.357 117.579 1.00 62.14 ? 13  GLN E CA  1 
ATOM   6512 C C   . GLN E 5 13  ? 108.688 186.286 118.421 1.00 61.85 ? 13  GLN E C   1 
ATOM   6513 O O   . GLN E 5 13  ? 108.940 185.269 119.073 1.00 59.01 ? 13  GLN E O   1 
ATOM   6514 C CB  . GLN E 5 13  ? 106.286 187.033 118.361 1.00 61.67 ? 13  GLN E CB  1 
ATOM   6515 C CG  . GLN E 5 13  ? 104.921 187.012 117.663 1.00 61.36 ? 13  GLN E CG  1 
ATOM   6516 C CD  . GLN E 5 13  ? 104.965 187.560 116.248 1.00 64.71 ? 13  GLN E CD  1 
ATOM   6517 O OE1 . GLN E 5 13  ? 105.736 188.470 115.947 1.00 65.50 ? 13  GLN E OE1 1 
ATOM   6518 N NE2 . GLN E 5 13  ? 104.145 186.996 115.369 1.00 64.95 ? 13  GLN E NE2 1 
ATOM   6519 N N   . PRO E 5 14  ? 109.529 187.328 118.399 1.00 56.37 ? 14  PRO E N   1 
ATOM   6520 C CA  . PRO E 5 14  ? 110.817 187.234 119.102 1.00 53.40 ? 14  PRO E CA  1 
ATOM   6521 C C   . PRO E 5 14  ? 110.634 187.070 120.603 1.00 56.11 ? 14  PRO E C   1 
ATOM   6522 O O   . PRO E 5 14  ? 109.727 187.648 121.206 1.00 58.43 ? 14  PRO E O   1 
ATOM   6523 C CB  . PRO E 5 14  ? 111.508 188.555 118.756 1.00 56.54 ? 14  PRO E CB  1 
ATOM   6524 C CG  . PRO E 5 14  ? 110.404 189.485 118.469 1.00 57.42 ? 14  PRO E CG  1 
ATOM   6525 C CD  . PRO E 5 14  ? 109.360 188.661 117.789 1.00 53.75 ? 14  PRO E CD  1 
ATOM   6526 N N   . GLY E 5 15  ? 111.509 186.265 121.201 1.00 51.00 ? 15  GLY E N   1 
ATOM   6527 C CA  . GLY E 5 15  ? 111.370 185.865 122.584 1.00 49.44 ? 15  GLY E CA  1 
ATOM   6528 C C   . GLY E 5 15  ? 110.463 184.674 122.819 1.00 52.90 ? 15  GLY E C   1 
ATOM   6529 O O   . GLY E 5 15  ? 110.352 184.223 123.965 1.00 52.93 ? 15  GLY E O   1 
ATOM   6530 N N   . GLY E 5 16  ? 109.819 184.142 121.772 1.00 54.58 ? 16  GLY E N   1 
ATOM   6531 C CA  . GLY E 5 16  ? 108.941 183.003 121.934 1.00 53.63 ? 16  GLY E CA  1 
ATOM   6532 C C   . GLY E 5 16  ? 109.689 181.682 121.977 1.00 53.46 ? 16  GLY E C   1 
ATOM   6533 O O   . GLY E 5 16  ? 110.916 181.630 121.912 1.00 56.25 ? 16  GLY E O   1 
ATOM   6534 N N   . SER E 5 17  ? 108.917 180.603 122.110 1.00 48.66 ? 17  SER E N   1 
ATOM   6535 C CA  . SER E 5 17  ? 109.432 179.240 122.169 1.00 50.13 ? 17  SER E CA  1 
ATOM   6536 C C   . SER E 5 17  ? 108.684 178.364 121.174 1.00 53.20 ? 17  SER E C   1 
ATOM   6537 O O   . SER E 5 17  ? 107.460 178.477 121.043 1.00 52.41 ? 17  SER E O   1 
ATOM   6538 C CB  . SER E 5 17  ? 109.293 178.671 123.582 1.00 54.34 ? 17  SER E CB  1 
ATOM   6539 O OG  . SER E 5 17  ? 109.492 179.681 124.555 1.00 57.48 ? 17  SER E OG  1 
ATOM   6540 N N   . ARG E 5 18  ? 109.421 177.499 120.474 1.00 53.11 ? 18  ARG E N   1 
ATOM   6541 C CA  . ARG E 5 18  ? 108.853 176.545 119.530 1.00 49.25 ? 18  ARG E CA  1 
ATOM   6542 C C   . ARG E 5 18  ? 109.621 175.233 119.604 1.00 43.46 ? 18  ARG E C   1 
ATOM   6543 O O   . ARG E 5 18  ? 110.802 175.209 119.958 1.00 46.39 ? 18  ARG E O   1 
ATOM   6544 C CB  . ARG E 5 18  ? 108.883 177.102 118.092 1.00 48.13 ? 18  ARG E CB  1 
ATOM   6545 C CG  . ARG E 5 18  ? 108.238 176.234 116.999 1.00 49.68 ? 18  ARG E CG  1 
ATOM   6546 C CD  . ARG E 5 18  ? 106.756 175.953 117.228 1.00 49.76 ? 18  ARG E CD  1 
ATOM   6547 N NE  . ARG E 5 18  ? 105.955 177.176 117.201 1.00 47.27 ? 18  ARG E NE  1 
ATOM   6548 C CZ  . ARG E 5 18  ? 105.264 177.641 116.165 1.00 49.26 ? 18  ARG E CZ  1 
ATOM   6549 N NH1 . ARG E 5 18  ? 105.260 177.033 114.988 1.00 51.76 ? 18  ARG E NH1 1 
ATOM   6550 N NH2 . ARG E 5 18  ? 104.557 178.758 116.311 1.00 48.33 ? 18  ARG E NH2 1 
ATOM   6551 N N   . LYS E 5 19  ? 108.930 174.141 119.271 1.00 35.57 ? 19  LYS E N   1 
ATOM   6552 C CA  . LYS E 5 19  ? 109.508 172.803 119.213 1.00 40.45 ? 19  LYS E CA  1 
ATOM   6553 C C   . LYS E 5 19  ? 109.470 172.297 117.779 1.00 43.68 ? 19  LYS E C   1 
ATOM   6554 O O   . LYS E 5 19  ? 108.436 172.395 117.110 1.00 44.88 ? 19  LYS E O   1 
ATOM   6555 C CB  . LYS E 5 19  ? 108.757 171.830 120.126 1.00 40.87 ? 19  LYS E CB  1 
ATOM   6556 C CG  . LYS E 5 19  ? 109.554 170.575 120.463 1.00 38.58 ? 19  LYS E CG  1 
ATOM   6557 C CD  . LYS E 5 19  ? 108.702 169.491 121.107 1.00 35.42 ? 19  LYS E CD  1 
ATOM   6558 C CE  . LYS E 5 19  ? 109.216 169.141 122.491 1.00 37.71 ? 19  LYS E CE  1 
ATOM   6559 N NZ  . LYS E 5 19  ? 108.411 168.072 123.137 1.00 45.08 ? 19  LYS E NZ  1 
ATOM   6560 N N   . LEU E 5 20  ? 110.599 171.762 117.317 1.00 35.90 ? 20  LEU E N   1 
ATOM   6561 C CA  . LEU E 5 20  ? 110.722 171.123 116.014 1.00 34.44 ? 20  LEU E CA  1 
ATOM   6562 C C   . LEU E 5 20  ? 111.044 169.657 116.236 1.00 34.79 ? 20  LEU E C   1 
ATOM   6563 O O   . LEU E 5 20  ? 111.895 169.334 117.070 1.00 35.66 ? 20  LEU E O   1 
ATOM   6564 C CB  . LEU E 5 20  ? 111.826 171.769 115.173 1.00 33.13 ? 20  LEU E CB  1 
ATOM   6565 C CG  . LEU E 5 20  ? 111.739 173.261 114.854 1.00 38.78 ? 20  LEU E CG  1 
ATOM   6566 C CD1 . LEU E 5 20  ? 112.738 173.602 113.766 1.00 36.86 ? 20  LEU E CD1 1 
ATOM   6567 C CD2 . LEU E 5 20  ? 110.339 173.683 114.444 1.00 47.02 ? 20  LEU E CD2 1 
ATOM   6568 N N   . SER E 5 21  ? 110.362 168.780 115.498 1.00 34.33 ? 21  SER E N   1 
ATOM   6569 C CA  . SER E 5 21  ? 110.556 167.338 115.580 1.00 34.20 ? 21  SER E CA  1 
ATOM   6570 C C   . SER E 5 21  ? 110.816 166.772 114.191 1.00 38.10 ? 21  SER E C   1 
ATOM   6571 O O   . SER E 5 21  ? 110.219 167.239 113.215 1.00 30.74 ? 21  SER E O   1 
ATOM   6572 C CB  . SER E 5 21  ? 109.339 166.654 116.207 1.00 38.07 ? 21  SER E CB  1 
ATOM   6573 O OG  . SER E 5 21  ? 108.136 167.149 115.652 1.00 44.81 ? 21  SER E OG  1 
ATOM   6574 N N   . CYS E 5 22  ? 111.711 165.780 114.101 1.00 33.44 ? 22  CYS E N   1 
ATOM   6575 C CA  . CYS E 5 22  ? 111.909 165.001 112.881 1.00 31.62 ? 22  CYS E CA  1 
ATOM   6576 C C   . CYS E 5 22  ? 111.605 163.541 113.184 1.00 31.81 ? 22  CYS E C   1 
ATOM   6577 O O   . CYS E 5 22  ? 112.040 163.014 114.212 1.00 36.01 ? 22  CYS E O   1 
ATOM   6578 C CB  . CYS E 5 22  ? 113.331 165.145 112.303 1.00 35.31 ? 22  CYS E CB  1 
ATOM   6579 S SG  . CYS E 5 22  ? 114.622 164.071 112.958 1.00 58.29 ? 22  CYS E SG  1 
ATOM   6580 N N   . SER E 5 23  ? 110.839 162.905 112.298 1.00 38.20 ? 23  SER E N   1 
ATOM   6581 C CA  . SER E 5 23  ? 110.388 161.528 112.465 1.00 35.95 ? 23  SER E CA  1 
ATOM   6582 C C   . SER E 5 23  ? 111.204 160.614 111.562 1.00 32.93 ? 23  SER E C   1 
ATOM   6583 O O   . SER E 5 23  ? 111.364 160.894 110.371 1.00 38.60 ? 23  SER E O   1 
ATOM   6584 C CB  . SER E 5 23  ? 108.901 161.404 112.134 1.00 42.78 ? 23  SER E CB  1 
ATOM   6585 O OG  . SER E 5 23  ? 108.138 162.328 112.890 1.00 45.90 ? 23  SER E OG  1 
ATOM   6586 N N   . ALA E 5 24  ? 111.700 159.517 112.128 1.00 30.35 ? 24  ALA E N   1 
ATOM   6587 C CA  . ALA E 5 24  ? 112.596 158.595 111.443 1.00 31.09 ? 24  ALA E CA  1 
ATOM   6588 C C   . ALA E 5 24  ? 111.830 157.362 110.992 1.00 35.91 ? 24  ALA E C   1 
ATOM   6589 O O   . ALA E 5 24  ? 111.113 156.747 111.788 1.00 44.39 ? 24  ALA E O   1 
ATOM   6590 C CB  . ALA E 5 24  ? 113.749 158.183 112.356 1.00 32.00 ? 24  ALA E CB  1 
ATOM   6591 N N   . SER E 5 25  ? 111.987 157.006 109.718 1.00 33.59 ? 25  SER E N   1 
ATOM   6592 C CA  . SER E 5 25  ? 111.378 155.819 109.137 1.00 30.86 ? 25  SER E CA  1 
ATOM   6593 C C   . SER E 5 25  ? 112.408 155.077 108.303 1.00 32.98 ? 25  SER E C   1 
ATOM   6594 O O   . SER E 5 25  ? 113.183 155.693 107.568 1.00 42.81 ? 25  SER E O   1 
ATOM   6595 C CB  . SER E 5 25  ? 110.175 156.186 108.264 1.00 29.54 ? 25  SER E CB  1 
ATOM   6596 O OG  . SER E 5 25  ? 109.374 157.172 108.888 1.00 35.93 ? 25  SER E OG  1 
ATOM   6597 N N   . GLY E 5 26  ? 112.410 153.753 108.418 1.00 22.01 ? 26  GLY E N   1 
ATOM   6598 C CA  . GLY E 5 26  ? 113.216 152.922 107.550 1.00 22.47 ? 26  GLY E CA  1 
ATOM   6599 C C   . GLY E 5 26  ? 114.652 152.710 107.969 1.00 28.52 ? 26  GLY E C   1 
ATOM   6600 O O   . GLY E 5 26  ? 115.424 152.157 107.178 1.00 32.20 ? 26  GLY E O   1 
ATOM   6601 N N   . PHE E 5 27  ? 115.049 153.134 109.169 1.00 27.07 ? 27  PHE E N   1 
ATOM   6602 C CA  . PHE E 5 27  ? 116.390 152.854 109.665 1.00 24.87 ? 27  PHE E CA  1 
ATOM   6603 C C   . PHE E 5 27  ? 116.358 152.695 111.177 1.00 34.06 ? 27  PHE E C   1 
ATOM   6604 O O   . PHE E 5 27  ? 115.441 153.160 111.857 1.00 32.76 ? 27  PHE E O   1 
ATOM   6605 C CB  . PHE E 5 27  ? 117.404 153.934 109.227 1.00 18.35 ? 27  PHE E CB  1 
ATOM   6606 C CG  . PHE E 5 27  ? 117.226 155.273 109.875 1.00 21.01 ? 27  PHE E CG  1 
ATOM   6607 C CD1 . PHE E 5 27  ? 116.363 156.207 109.337 1.00 19.18 ? 27  PHE E CD1 1 
ATOM   6608 C CD2 . PHE E 5 27  ? 117.977 155.623 110.978 1.00 22.27 ? 27  PHE E CD2 1 
ATOM   6609 C CE1 . PHE E 5 27  ? 116.221 157.442 109.917 1.00 25.81 ? 27  PHE E CE1 1 
ATOM   6610 C CE2 . PHE E 5 27  ? 117.838 156.857 111.558 1.00 25.23 ? 27  PHE E CE2 1 
ATOM   6611 C CZ  . PHE E 5 27  ? 116.961 157.766 111.029 1.00 27.82 ? 27  PHE E CZ  1 
ATOM   6612 N N   . ALA E 5 28  ? 117.378 152.008 111.690 1.00 26.66 ? 28  ALA E N   1 
ATOM   6613 C CA  . ALA E 5 28  ? 117.503 151.711 113.116 1.00 21.55 ? 28  ALA E CA  1 
ATOM   6614 C C   . ALA E 5 28  ? 117.862 153.003 113.834 1.00 25.28 ? 28  ALA E C   1 
ATOM   6615 O O   . ALA E 5 28  ? 119.032 153.322 114.034 1.00 30.59 ? 28  ALA E O   1 
ATOM   6616 C CB  . ALA E 5 28  ? 118.552 150.633 113.350 1.00 19.87 ? 28  ALA E CB  1 
ATOM   6617 N N   . PHE E 5 29  ? 116.828 153.744 114.241 1.00 22.47 ? 29  PHE E N   1 
ATOM   6618 C CA  . PHE E 5 29  ? 117.027 155.097 114.755 1.00 13.35 ? 29  PHE E CA  1 
ATOM   6619 C C   . PHE E 5 29  ? 117.829 155.098 116.050 1.00 16.76 ? 29  PHE E C   1 
ATOM   6620 O O   . PHE E 5 29  ? 118.528 156.073 116.350 1.00 27.02 ? 29  PHE E O   1 
ATOM   6621 C CB  . PHE E 5 29  ? 115.670 155.772 114.956 1.00 25.37 ? 29  PHE E CB  1 
ATOM   6622 C CG  . PHE E 5 29  ? 115.753 157.149 115.550 1.00 30.96 ? 29  PHE E CG  1 
ATOM   6623 C CD1 . PHE E 5 29  ? 116.049 158.240 114.756 1.00 32.10 ? 29  PHE E CD1 1 
ATOM   6624 C CD2 . PHE E 5 29  ? 115.538 157.352 116.902 1.00 29.70 ? 29  PHE E CD2 1 
ATOM   6625 C CE1 . PHE E 5 29  ? 116.125 159.506 115.295 1.00 26.59 ? 29  PHE E CE1 1 
ATOM   6626 C CE2 . PHE E 5 29  ? 115.615 158.617 117.445 1.00 24.82 ? 29  PHE E CE2 1 
ATOM   6627 C CZ  . PHE E 5 29  ? 115.910 159.694 116.641 1.00 23.41 ? 29  PHE E CZ  1 
ATOM   6628 N N   . SER E 5 30  ? 117.740 154.023 116.833 1.00 16.38 ? 30  SER E N   1 
ATOM   6629 C CA  . SER E 5 30  ? 118.477 153.969 118.090 1.00 23.81 ? 30  SER E CA  1 
ATOM   6630 C C   . SER E 5 30  ? 119.982 153.944 117.852 1.00 27.69 ? 30  SER E C   1 
ATOM   6631 O O   . SER E 5 30  ? 120.749 154.540 118.616 1.00 31.61 ? 30  SER E O   1 
ATOM   6632 C CB  . SER E 5 30  ? 118.040 152.745 118.891 1.00 27.51 ? 30  SER E CB  1 
ATOM   6633 O OG  . SER E 5 30  ? 116.632 152.714 119.032 1.00 29.49 ? 30  SER E OG  1 
ATOM   6634 N N   . SER E 5 31  ? 120.423 153.250 116.801 1.00 19.02 ? 31  SER E N   1 
ATOM   6635 C CA  . SER E 5 31  ? 121.854 153.108 116.551 1.00 24.43 ? 31  SER E CA  1 
ATOM   6636 C C   . SER E 5 31  ? 122.482 154.417 116.085 1.00 23.78 ? 31  SER E C   1 
ATOM   6637 O O   . SER E 5 31  ? 123.655 154.685 116.371 1.00 23.50 ? 31  SER E O   1 
ATOM   6638 C CB  . SER E 5 31  ? 122.091 152.007 115.519 1.00 21.91 ? 31  SER E CB  1 
ATOM   6639 O OG  . SER E 5 31  ? 121.841 150.729 116.076 1.00 21.84 ? 31  SER E OG  1 
ATOM   6640 N N   . PHE E 5 32  ? 121.728 155.238 115.359 1.00 21.64 ? 32  PHE E N   1 
ATOM   6641 C CA  . PHE E 5 32  ? 122.287 156.413 114.704 1.00 10.65 ? 32  PHE E CA  1 
ATOM   6642 C C   . PHE E 5 32  ? 122.376 157.596 115.658 1.00 21.20 ? 32  PHE E C   1 
ATOM   6643 O O   . PHE E 5 32  ? 121.391 157.954 116.309 1.00 33.96 ? 32  PHE E O   1 
ATOM   6644 C CB  . PHE E 5 32  ? 121.433 156.797 113.498 1.00 10.50 ? 32  PHE E CB  1 
ATOM   6645 C CG  . PHE E 5 32  ? 121.734 156.002 112.269 1.00 19.52 ? 32  PHE E CG  1 
ATOM   6646 C CD1 . PHE E 5 32  ? 121.240 154.725 112.119 1.00 15.19 ? 32  PHE E CD1 1 
ATOM   6647 C CD2 . PHE E 5 32  ? 122.507 156.537 111.258 1.00 22.02 ? 32  PHE E CD2 1 
ATOM   6648 C CE1 . PHE E 5 32  ? 121.513 153.995 110.992 1.00 14.13 ? 32  PHE E CE1 1 
ATOM   6649 C CE2 . PHE E 5 32  ? 122.785 155.809 110.127 1.00 17.64 ? 32  PHE E CE2 1 
ATOM   6650 C CZ  . PHE E 5 32  ? 122.287 154.536 109.993 1.00 21.36 ? 32  PHE E CZ  1 
ATOM   6651 N N   . GLY E 5 33  ? 123.557 158.205 115.734 1.00 19.26 ? 33  GLY E N   1 
ATOM   6652 C CA  . GLY E 5 33  ? 123.664 159.526 116.328 1.00 16.38 ? 33  GLY E CA  1 
ATOM   6653 C C   . GLY E 5 33  ? 123.092 160.574 115.390 1.00 15.19 ? 33  GLY E C   1 
ATOM   6654 O O   . GLY E 5 33  ? 123.268 160.507 114.173 1.00 34.53 ? 33  GLY E O   1 
ATOM   6655 N N   . MET E 5 34  ? 122.412 161.565 115.969 1.00 12.91 ? 34  MET E N   1 
ATOM   6656 C CA  . MET E 5 34  ? 121.573 162.491 115.219 1.00 18.66 ? 34  MET E CA  1 
ATOM   6657 C C   . MET E 5 34  ? 121.981 163.929 115.502 1.00 16.83 ? 34  MET E C   1 
ATOM   6658 O O   . MET E 5 34  ? 122.420 164.257 116.606 1.00 29.02 ? 34  MET E O   1 
ATOM   6659 C CB  . MET E 5 34  ? 120.095 162.300 115.566 1.00 16.24 ? 34  MET E CB  1 
ATOM   6660 C CG  . MET E 5 34  ? 119.539 160.915 115.211 1.00 20.38 ? 34  MET E CG  1 
ATOM   6661 S SD  . MET E 5 34  ? 118.981 160.656 113.509 1.00 34.06 ? 34  MET E SD  1 
ATOM   6662 C CE  . MET E 5 34  ? 117.835 162.005 113.244 1.00 22.72 ? 34  MET E CE  1 
ATOM   6663 N N   . HIS E 5 35  ? 121.824 164.778 114.487 1.00 13.57 ? 35  HIS E N   1 
ATOM   6664 C CA  . HIS E 5 35  ? 122.150 166.202 114.573 1.00 18.11 ? 35  HIS E CA  1 
ATOM   6665 C C   . HIS E 5 35  ? 120.917 167.052 114.300 1.00 25.69 ? 35  HIS E C   1 
ATOM   6666 O O   . HIS E 5 35  ? 121.026 168.205 113.885 1.00 10.16 ? 35  HIS E O   1 
ATOM   6667 C CB  . HIS E 5 35  ? 123.250 166.568 113.581 1.00 26.21 ? 35  HIS E CB  1 
ATOM   6668 C CG  . HIS E 5 35  ? 124.533 165.833 113.797 1.00 24.74 ? 35  HIS E CG  1 
ATOM   6669 N ND1 . HIS E 5 35  ? 124.783 164.594 113.252 1.00 18.24 ? 35  HIS E ND1 1 
ATOM   6670 C CD2 . HIS E 5 35  ? 125.644 166.168 114.493 1.00 26.24 ? 35  HIS E CD2 1 
ATOM   6671 C CE1 . HIS E 5 35  ? 125.992 164.197 113.606 1.00 10.71 ? 35  HIS E CE1 1 
ATOM   6672 N NE2 . HIS E 5 35  ? 126.534 165.133 114.361 1.00 14.41 ? 35  HIS E NE2 1 
ATOM   6673 N N   . VAL E 5 37  ? 121.562 170.802 112.296 1.00 11.10 ? 37  VAL E N   1 
ATOM   6674 C CA  . VAL E 5 37  ? 122.100 171.640 111.232 1.00 18.08 ? 37  VAL E CA  1 
ATOM   6675 C C   . VAL E 5 37  ? 120.989 172.533 110.697 1.00 13.49 ? 37  VAL E C   1 
ATOM   6676 O O   . VAL E 5 37  ? 119.877 172.061 110.482 1.00 28.82 ? 37  VAL E O   1 
ATOM   6677 C CB  . VAL E 5 37  ? 122.724 170.789 110.102 1.00 10.02 ? 37  VAL E CB  1 
ATOM   6678 C CG1 . VAL E 5 37  ? 123.257 171.686 108.994 1.00 5.13  ? 37  VAL E CG1 1 
ATOM   6679 C CG2 . VAL E 5 37  ? 123.823 169.877 110.649 1.00 3.27  ? 37  VAL E CG2 1 
ATOM   6680 N N   . ARG E 5 38  ? 121.289 173.820 110.498 1.00 17.37 ? 38  ARG E N   1 
ATOM   6681 C CA  . ARG E 5 38  ? 120.343 174.779 109.940 1.00 17.41 ? 38  ARG E CA  1 
ATOM   6682 C C   . ARG E 5 38  ? 121.002 175.553 108.811 1.00 31.78 ? 38  ARG E C   1 
ATOM   6683 O O   . ARG E 5 38  ? 122.231 175.637 108.743 1.00 44.67 ? 38  ARG E O   1 
ATOM   6684 C CB  . ARG E 5 38  ? 119.826 175.781 110.980 1.00 22.62 ? 38  ARG E CB  1 
ATOM   6685 C CG  . ARG E 5 38  ? 120.889 176.570 111.726 1.00 24.01 ? 38  ARG E CG  1 
ATOM   6686 C CD  . ARG E 5 38  ? 120.235 177.538 112.695 1.00 27.32 ? 38  ARG E CD  1 
ATOM   6687 N NE  . ARG E 5 38  ? 121.197 178.240 113.539 1.00 33.86 ? 38  ARG E NE  1 
ATOM   6688 C CZ  . ARG E 5 38  ? 120.892 178.935 114.629 1.00 28.99 ? 38  ARG E CZ  1 
ATOM   6689 N NH1 . ARG E 5 38  ? 119.644 179.054 115.058 1.00 25.01 ? 38  ARG E NH1 1 
ATOM   6690 N NH2 . ARG E 5 38  ? 121.866 179.529 115.309 1.00 36.78 ? 38  ARG E NH2 1 
ATOM   6691 N N   . GLN E 5 39  ? 120.176 176.105 107.925 1.00 28.61 ? 39  GLN E N   1 
ATOM   6692 C CA  . GLN E 5 39  ? 120.622 177.007 106.872 1.00 28.58 ? 39  GLN E CA  1 
ATOM   6693 C C   . GLN E 5 39  ? 119.828 178.302 106.936 1.00 38.01 ? 39  GLN E C   1 
ATOM   6694 O O   . GLN E 5 39  ? 118.598 178.286 106.834 1.00 46.64 ? 39  GLN E O   1 
ATOM   6695 C CB  . GLN E 5 39  ? 120.466 176.373 105.490 1.00 33.92 ? 39  GLN E CB  1 
ATOM   6696 C CG  . GLN E 5 39  ? 121.183 177.148 104.394 1.00 38.68 ? 39  GLN E CG  1 
ATOM   6697 C CD  . GLN E 5 39  ? 121.426 176.343 103.142 1.00 37.25 ? 39  GLN E CD  1 
ATOM   6698 O OE1 . GLN E 5 39  ? 121.627 175.134 103.197 1.00 36.19 ? 39  GLN E OE1 1 
ATOM   6699 N NE2 . GLN E 5 39  ? 121.414 177.017 101.999 1.00 36.38 ? 39  GLN E NE2 1 
ATOM   6700 N N   . ALA E 5 40  ? 120.540 179.419 107.060 1.00 41.82 ? 40  ALA E N   1 
ATOM   6701 C CA  . ALA E 5 40  ? 119.919 180.729 106.977 1.00 41.64 ? 40  ALA E CA  1 
ATOM   6702 C C   . ALA E 5 40  ? 119.338 180.915 105.574 1.00 43.99 ? 40  ALA E C   1 
ATOM   6703 O O   . ALA E 5 40  ? 119.687 180.164 104.662 1.00 49.01 ? 40  ALA E O   1 
ATOM   6704 C CB  . ALA E 5 40  ? 120.944 181.812 107.313 1.00 44.14 ? 40  ALA E CB  1 
ATOM   6705 N N   . PRO E 5 41  ? 118.431 181.896 105.380 1.00 52.39 ? 41  PRO E N   1 
ATOM   6706 C CA  . PRO E 5 41  ? 117.576 181.883 104.170 1.00 53.54 ? 41  PRO E CA  1 
ATOM   6707 C C   . PRO E 5 41  ? 118.325 181.874 102.846 1.00 56.73 ? 41  PRO E C   1 
ATOM   6708 O O   . PRO E 5 41  ? 117.862 181.236 101.891 1.00 57.01 ? 41  PRO E O   1 
ATOM   6709 C CB  . PRO E 5 41  ? 116.751 183.167 104.319 1.00 54.25 ? 41  PRO E CB  1 
ATOM   6710 C CG  . PRO E 5 41  ? 116.715 183.418 105.764 1.00 54.89 ? 41  PRO E CG  1 
ATOM   6711 C CD  . PRO E 5 41  ? 118.059 183.009 106.273 1.00 48.98 ? 41  PRO E CD  1 
ATOM   6712 N N   . GLU E 5 42  ? 119.467 182.560 102.766 1.00 61.68 ? 42  GLU E N   1 
ATOM   6713 C CA  . GLU E 5 42  ? 120.333 182.542 101.593 1.00 61.53 ? 42  GLU E CA  1 
ATOM   6714 C C   . GLU E 5 42  ? 121.800 182.281 101.926 1.00 62.73 ? 42  GLU E C   1 
ATOM   6715 O O   . GLU E 5 42  ? 122.631 182.308 101.010 1.00 65.57 ? 42  GLU E O   1 
ATOM   6716 C CB  . GLU E 5 42  ? 120.218 183.865 100.834 1.00 59.08 ? 42  GLU E CB  1 
ATOM   6717 N N   . LYS E 5 43  ? 122.141 182.020 103.197 1.00 51.97 ? 43  LYS E N   1 
ATOM   6718 C CA  . LYS E 5 43  ? 123.528 181.900 103.637 1.00 50.01 ? 43  LYS E CA  1 
ATOM   6719 C C   . LYS E 5 43  ? 123.830 180.435 103.920 1.00 46.94 ? 43  LYS E C   1 
ATOM   6720 O O   . LYS E 5 43  ? 122.991 179.558 103.713 1.00 47.07 ? 43  LYS E O   1 
ATOM   6721 C CB  . LYS E 5 43  ? 123.881 182.747 104.894 1.00 48.98 ? 43  LYS E CB  1 
ATOM   6722 C CG  . LYS E 5 43  ? 123.415 184.242 105.109 1.00 51.00 ? 43  LYS E CG  1 
ATOM   6723 C CD  . LYS E 5 43  ? 122.944 185.068 103.902 1.00 52.84 ? 43  LYS E CD  1 
ATOM   6724 C CE  . LYS E 5 43  ? 122.114 186.270 104.333 1.00 56.14 ? 43  LYS E CE  1 
ATOM   6725 N NZ  . LYS E 5 43  ? 120.727 185.860 104.661 1.00 55.57 ? 43  LYS E NZ  1 
ATOM   6726 N N   . GLY E 5 44  ? 125.052 180.179 104.385 1.00 38.58 ? 44  GLY E N   1 
ATOM   6727 C CA  . GLY E 5 44  ? 125.549 178.821 104.469 1.00 39.28 ? 44  GLY E CA  1 
ATOM   6728 C C   . GLY E 5 44  ? 125.002 178.039 105.649 1.00 38.38 ? 44  GLY E C   1 
ATOM   6729 O O   . GLY E 5 44  ? 124.243 178.535 106.481 1.00 37.77 ? 44  GLY E O   1 
ATOM   6730 N N   . LEU E 5 45  ? 125.400 176.767 105.700 1.00 27.61 ? 45  LEU E N   1 
ATOM   6731 C CA  . LEU E 5 45  ? 124.972 175.870 106.767 1.00 24.04 ? 45  LEU E CA  1 
ATOM   6732 C C   . LEU E 5 45  ? 125.731 176.133 108.063 1.00 27.72 ? 45  LEU E C   1 
ATOM   6733 O O   . LEU E 5 45  ? 126.886 176.565 108.051 1.00 38.61 ? 45  LEU E O   1 
ATOM   6734 C CB  . LEU E 5 45  ? 125.179 174.414 106.342 1.00 26.39 ? 45  LEU E CB  1 
ATOM   6735 C CG  . LEU E 5 45  ? 124.323 173.864 105.200 1.00 23.84 ? 45  LEU E CG  1 
ATOM   6736 C CD1 . LEU E 5 45  ? 124.966 172.630 104.603 1.00 25.37 ? 45  LEU E CD1 1 
ATOM   6737 C CD2 . LEU E 5 45  ? 122.935 173.527 105.705 1.00 24.49 ? 45  LEU E CD2 1 
ATOM   6738 N N   . GLU E 5 46  ? 125.065 175.865 109.188 1.00 21.76 ? 46  GLU E N   1 
ATOM   6739 C CA  . GLU E 5 46  ? 125.663 175.915 110.515 1.00 15.03 ? 46  GLU E CA  1 
ATOM   6740 C C   . GLU E 5 46  ? 125.088 174.788 111.362 1.00 20.30 ? 46  GLU E C   1 
ATOM   6741 O O   . GLU E 5 46  ? 123.898 174.479 111.263 1.00 35.09 ? 46  GLU E O   1 
ATOM   6742 C CB  . GLU E 5 46  ? 125.406 177.265 111.191 1.00 11.91 ? 46  GLU E CB  1 
ATOM   6743 N N   . TRP E 5 47  ? 125.926 174.194 112.209 1.00 17.25 ? 47  TRP E N   1 
ATOM   6744 C CA  . TRP E 5 47  ? 125.565 172.996 112.965 1.00 12.97 ? 47  TRP E CA  1 
ATOM   6745 C C   . TRP E 5 47  ? 125.017 173.422 114.324 1.00 21.46 ? 47  TRP E C   1 
ATOM   6746 O O   . TRP E 5 47  ? 125.656 174.200 115.039 1.00 31.50 ? 47  TRP E O   1 
ATOM   6747 C CB  . TRP E 5 47  ? 126.778 172.076 113.099 1.00 7.72  ? 47  TRP E CB  1 
ATOM   6748 C CG  . TRP E 5 47  ? 126.785 171.171 114.296 1.00 10.41 ? 47  TRP E CG  1 
ATOM   6749 C CD1 . TRP E 5 47  ? 126.296 169.903 114.363 1.00 8.99  ? 47  TRP E CD1 1 
ATOM   6750 C CD2 . TRP E 5 47  ? 127.339 171.455 115.588 1.00 23.89 ? 47  TRP E CD2 1 
ATOM   6751 N NE1 . TRP E 5 47  ? 126.497 169.385 115.618 1.00 21.23 ? 47  TRP E NE1 1 
ATOM   6752 C CE2 . TRP E 5 47  ? 127.133 170.320 116.388 1.00 17.99 ? 47  TRP E CE2 1 
ATOM   6753 C CE3 . TRP E 5 47  ? 127.975 172.565 116.147 1.00 24.16 ? 47  TRP E CE3 1 
ATOM   6754 C CZ2 . TRP E 5 47  ? 127.544 170.260 117.713 1.00 12.27 ? 47  TRP E CZ2 1 
ATOM   6755 C CZ3 . TRP E 5 47  ? 128.375 172.504 117.459 1.00 18.32 ? 47  TRP E CZ3 1 
ATOM   6756 C CH2 . TRP E 5 47  ? 128.163 171.360 118.228 1.00 13.34 ? 47  TRP E CH2 1 
ATOM   6757 N N   . VAL E 5 48  ? 123.829 172.916 114.676 1.00 24.42 ? 48  VAL E N   1 
ATOM   6758 C CA  . VAL E 5 48  ? 123.148 173.363 115.891 1.00 24.26 ? 48  VAL E CA  1 
ATOM   6759 C C   . VAL E 5 48  ? 123.499 172.471 117.077 1.00 24.25 ? 48  VAL E C   1 
ATOM   6760 O O   . VAL E 5 48  ? 124.036 172.946 118.083 1.00 42.92 ? 48  VAL E O   1 
ATOM   6761 C CB  . VAL E 5 48  ? 121.627 173.419 115.658 1.00 23.03 ? 48  VAL E CB  1 
ATOM   6762 C CG1 . VAL E 5 48  ? 120.879 173.638 116.972 1.00 19.68 ? 48  VAL E CG1 1 
ATOM   6763 C CG2 . VAL E 5 48  ? 121.287 174.510 114.663 1.00 22.35 ? 48  VAL E CG2 1 
ATOM   6764 N N   . ALA E 5 49  ? 123.200 171.175 116.987 1.00 7.57  ? 49  ALA E N   1 
ATOM   6765 C CA  . ALA E 5 49  ? 123.281 170.288 118.141 1.00 6.65  ? 49  ALA E CA  1 
ATOM   6766 C C   . ALA E 5 49  ? 123.531 168.863 117.675 1.00 8.58  ? 49  ALA E C   1 
ATOM   6767 O O   . ALA E 5 49  ? 123.392 168.546 116.493 1.00 33.70 ? 49  ALA E O   1 
ATOM   6768 C CB  . ALA E 5 49  ? 122.003 170.352 118.982 1.00 15.97 ? 49  ALA E CB  1 
ATOM   6769 N N   . TYR E 5 50  ? 123.917 168.011 118.624 1.00 7.35  ? 50  TYR E N   1 
ATOM   6770 C CA  . TYR E 5 50  ? 124.207 166.604 118.376 1.00 2.40  ? 50  TYR E CA  1 
ATOM   6771 C C   . TYR E 5 50  ? 123.724 165.792 119.566 1.00 20.01 ? 50  TYR E C   1 
ATOM   6772 O O   . TYR E 5 50  ? 123.867 166.233 120.707 1.00 44.51 ? 50  TYR E O   1 
ATOM   6773 C CB  . TYR E 5 50  ? 125.706 166.384 118.170 1.00 11.56 ? 50  TYR E CB  1 
ATOM   6774 C CG  . TYR E 5 50  ? 126.146 164.939 118.228 1.00 1.31  ? 50  TYR E CG  1 
ATOM   6775 C CD1 . TYR E 5 50  ? 125.754 164.032 117.260 1.00 22.31 ? 50  TYR E CD1 1 
ATOM   6776 C CD2 . TYR E 5 50  ? 126.957 164.483 119.252 1.00 0.00  ? 50  TYR E CD2 1 
ATOM   6777 C CE1 . TYR E 5 50  ? 126.162 162.717 117.309 1.00 21.46 ? 50  TYR E CE1 1 
ATOM   6778 C CE2 . TYR E 5 50  ? 127.369 163.174 119.311 1.00 6.14  ? 50  TYR E CE2 1 
ATOM   6779 C CZ  . TYR E 5 50  ? 126.969 162.294 118.339 1.00 14.09 ? 50  TYR E CZ  1 
ATOM   6780 O OH  . TYR E 5 50  ? 127.380 160.986 118.399 1.00 15.35 ? 50  TYR E OH  1 
ATOM   6781 N N   . ILE E 5 51  ? 123.132 164.628 119.302 1.00 17.35 ? 51  ILE E N   1 
ATOM   6782 C CA  . ILE E 5 51  ? 122.754 163.666 120.335 1.00 15.72 ? 51  ILE E CA  1 
ATOM   6783 C C   . ILE E 5 51  ? 123.322 162.312 119.925 1.00 25.24 ? 51  ILE E C   1 
ATOM   6784 O O   . ILE E 5 51  ? 123.150 161.880 118.779 1.00 34.51 ? 51  ILE E O   1 
ATOM   6785 C CB  . ILE E 5 51  ? 121.225 163.623 120.532 1.00 15.30 ? 51  ILE E CB  1 
ATOM   6786 C CG1 . ILE E 5 51  ? 120.800 162.720 121.704 1.00 27.20 ? 51  ILE E CG1 1 
ATOM   6787 C CG2 . ILE E 5 51  ? 120.519 163.131 119.291 1.00 27.63 ? 51  ILE E CG2 1 
ATOM   6788 C CD1 . ILE E 5 51  ? 120.942 163.342 123.058 1.00 29.57 ? 51  ILE E CD1 1 
ATOM   6789 N N   . SER E 5 52  ? 124.010 161.654 120.850 1.00 10.85 ? 52  SER E N   1 
ATOM   6790 C CA  . SER E 5 52  ? 124.623 160.371 120.553 1.00 9.84  ? 52  SER E CA  1 
ATOM   6791 C C   . SER E 5 52  ? 123.577 159.263 120.567 1.00 15.71 ? 52  SER E C   1 
ATOM   6792 O O   . SER E 5 52  ? 122.410 159.478 120.900 1.00 34.91 ? 52  SER E O   1 
ATOM   6793 C CB  . SER E 5 52  ? 125.720 160.061 121.565 1.00 20.67 ? 52  SER E CB  1 
ATOM   6794 O OG  . SER E 5 52  ? 126.105 158.702 121.502 1.00 30.81 ? 52  SER E OG  1 
ATOM   6795 N N   . SER E 5 53  ? 124.002 158.065 120.173 1.00 12.91 ? 53  SER E N   1 
ATOM   6796 C CA  . SER E 5 53  ? 123.145 156.899 120.328 1.00 18.07 ? 53  SER E CA  1 
ATOM   6797 C C   . SER E 5 53  ? 122.956 156.596 121.809 1.00 30.54 ? 53  SER E C   1 
ATOM   6798 O O   . SER E 5 53  ? 123.922 156.522 122.573 1.00 33.61 ? 53  SER E O   1 
ATOM   6799 C CB  . SER E 5 53  ? 123.747 155.691 119.612 1.00 22.98 ? 53  SER E CB  1 
ATOM   6800 O OG  . SER E 5 53  ? 124.961 155.287 120.222 1.00 28.94 ? 53  SER E OG  1 
ATOM   6801 N N   . GLY E 5 54  ? 121.703 156.415 122.213 1.00 31.40 ? 54  GLY E N   1 
ATOM   6802 C CA  . GLY E 5 54  ? 121.381 156.228 123.610 1.00 31.00 ? 54  GLY E CA  1 
ATOM   6803 C C   . GLY E 5 54  ? 121.287 157.498 124.428 1.00 30.93 ? 54  GLY E C   1 
ATOM   6804 O O   . GLY E 5 54  ? 121.077 157.410 125.644 1.00 39.45 ? 54  GLY E O   1 
ATOM   6805 N N   . SER E 5 55  ? 121.452 158.671 123.813 1.00 19.70 ? 55  SER E N   1 
ATOM   6806 C CA  . SER E 5 55  ? 121.332 159.983 124.444 1.00 17.41 ? 55  SER E CA  1 
ATOM   6807 C C   . SER E 5 55  ? 122.442 160.264 125.448 1.00 26.49 ? 55  SER E C   1 
ATOM   6808 O O   . SER E 5 55  ? 122.300 161.173 126.273 1.00 28.72 ? 55  SER E O   1 
ATOM   6809 C CB  . SER E 5 55  ? 119.976 160.158 125.138 1.00 24.65 ? 55  SER E CB  1 
ATOM   6810 O OG  . SER E 5 55  ? 118.912 159.828 124.265 1.00 28.72 ? 55  SER E OG  1 
ATOM   6811 N N   . GLY E 5 56  ? 123.544 159.514 125.404 1.00 21.56 ? 56  GLY E N   1 
ATOM   6812 C CA  . GLY E 5 56  ? 124.581 159.682 126.409 1.00 21.40 ? 56  GLY E CA  1 
ATOM   6813 C C   . GLY E 5 56  ? 125.292 161.020 126.326 1.00 26.71 ? 56  GLY E C   1 
ATOM   6814 O O   . GLY E 5 56  ? 125.602 161.630 127.352 1.00 34.22 ? 56  GLY E O   1 
ATOM   6815 N N   . THR E 5 57  ? 125.557 161.492 125.108 1.00 25.54 ? 57  THR E N   1 
ATOM   6816 C CA  . THR E 5 57  ? 126.393 162.660 124.849 1.00 18.96 ? 57  THR E CA  1 
ATOM   6817 C C   . THR E 5 57  ? 125.598 163.697 124.074 1.00 13.71 ? 57  THR E C   1 
ATOM   6818 O O   . THR E 5 57  ? 124.944 163.362 123.083 1.00 23.73 ? 57  THR E O   1 
ATOM   6819 C CB  . THR E 5 57  ? 127.642 162.267 124.057 1.00 16.22 ? 57  THR E CB  1 
ATOM   6820 O OG1 . THR E 5 57  ? 128.469 161.412 124.853 1.00 25.08 ? 57  THR E OG1 1 
ATOM   6821 C CG2 . THR E 5 57  ? 128.434 163.493 123.655 1.00 20.48 ? 57  THR E CG2 1 
ATOM   6822 N N   . ILE E 5 58  ? 125.666 164.951 124.521 1.00 13.99 ? 58  ILE E N   1 
ATOM   6823 C CA  . ILE E 5 58  ? 125.006 166.072 123.861 1.00 15.04 ? 58  ILE E CA  1 
ATOM   6824 C C   . ILE E 5 58  ? 126.026 167.189 123.698 1.00 26.52 ? 58  ILE E C   1 
ATOM   6825 O O   . ILE E 5 58  ? 126.795 167.471 124.624 1.00 36.44 ? 58  ILE E O   1 
ATOM   6826 C CB  . ILE E 5 58  ? 123.779 166.566 124.651 1.00 21.27 ? 58  ILE E CB  1 
ATOM   6827 C CG1 . ILE E 5 58  ? 122.954 165.357 125.117 1.00 25.30 ? 58  ILE E CG1 1 
ATOM   6828 C CG2 . ILE E 5 58  ? 122.938 167.508 123.770 1.00 19.79 ? 58  ILE E CG2 1 
ATOM   6829 C CD1 . ILE E 5 58  ? 121.518 165.628 125.562 1.00 24.23 ? 58  ILE E CD1 1 
ATOM   6830 N N   . TYR E 5 59  ? 126.039 167.809 122.517 1.00 13.91 ? 59  TYR E N   1 
ATOM   6831 C CA  . TYR E 5 59  ? 126.800 169.023 122.257 1.00 13.36 ? 59  TYR E CA  1 
ATOM   6832 C C   . TYR E 5 59  ? 125.888 170.047 121.602 1.00 19.35 ? 59  TYR E C   1 
ATOM   6833 O O   . TYR E 5 59  ? 124.953 169.684 120.885 1.00 26.14 ? 59  TYR E O   1 
ATOM   6834 C CB  . TYR E 5 59  ? 128.005 168.776 121.345 1.00 15.75 ? 59  TYR E CB  1 
ATOM   6835 C CG  . TYR E 5 59  ? 128.973 167.730 121.834 1.00 17.15 ? 59  TYR E CG  1 
ATOM   6836 C CD1 . TYR E 5 59  ? 129.770 167.950 122.944 1.00 23.36 ? 59  TYR E CD1 1 
ATOM   6837 C CD2 . TYR E 5 59  ? 129.120 166.536 121.156 1.00 18.67 ? 59  TYR E CD2 1 
ATOM   6838 C CE1 . TYR E 5 59  ? 130.662 166.992 123.377 1.00 26.63 ? 59  TYR E CE1 1 
ATOM   6839 C CE2 . TYR E 5 59  ? 130.007 165.579 121.575 1.00 14.77 ? 59  TYR E CE2 1 
ATOM   6840 C CZ  . TYR E 5 59  ? 130.775 165.807 122.685 1.00 24.99 ? 59  TYR E CZ  1 
ATOM   6841 O OH  . TYR E 5 59  ? 131.660 164.839 123.097 1.00 30.06 ? 59  TYR E OH  1 
ATOM   6842 N N   . TYR E 5 60  ? 126.157 171.323 121.870 1.00 20.83 ? 60  TYR E N   1 
ATOM   6843 C CA  . TYR E 5 60  ? 125.499 172.437 121.202 1.00 19.16 ? 60  TYR E CA  1 
ATOM   6844 C C   . TYR E 5 60  ? 126.554 173.442 120.772 1.00 27.99 ? 60  TYR E C   1 
ATOM   6845 O O   . TYR E 5 60  ? 127.630 173.527 121.369 1.00 28.96 ? 60  TYR E O   1 
ATOM   6846 C CB  . TYR E 5 60  ? 124.470 173.160 122.093 1.00 24.17 ? 60  TYR E CB  1 
ATOM   6847 C CG  . TYR E 5 60  ? 123.507 172.287 122.864 1.00 30.25 ? 60  TYR E CG  1 
ATOM   6848 C CD1 . TYR E 5 60  ? 123.890 171.655 124.037 1.00 30.72 ? 60  TYR E CD1 1 
ATOM   6849 C CD2 . TYR E 5 60  ? 122.200 172.127 122.435 1.00 20.09 ? 60  TYR E CD2 1 
ATOM   6850 C CE1 . TYR E 5 60  ? 123.010 170.870 124.740 1.00 27.00 ? 60  TYR E CE1 1 
ATOM   6851 C CE2 . TYR E 5 60  ? 121.313 171.345 123.135 1.00 15.87 ? 60  TYR E CE2 1 
ATOM   6852 C CZ  . TYR E 5 60  ? 121.723 170.723 124.287 1.00 23.46 ? 60  TYR E CZ  1 
ATOM   6853 O OH  . TYR E 5 60  ? 120.844 169.938 124.994 1.00 32.45 ? 60  TYR E OH  1 
ATOM   6854 N N   . ALA E 5 61  ? 126.241 174.201 119.728 1.00 27.98 ? 61  ALA E N   1 
ATOM   6855 C CA  . ALA E 5 61  ? 127.086 175.323 119.357 1.00 34.44 ? 61  ALA E CA  1 
ATOM   6856 C C   . ALA E 5 61  ? 126.948 176.429 120.395 1.00 35.33 ? 61  ALA E C   1 
ATOM   6857 O O   . ALA E 5 61  ? 125.996 176.457 121.178 1.00 45.71 ? 61  ALA E O   1 
ATOM   6858 C CB  . ALA E 5 61  ? 126.719 175.840 117.967 1.00 34.07 ? 61  ALA E CB  1 
ATOM   6859 N N   . ASP E 5 62  ? 127.925 177.338 120.411 1.00 39.84 ? 62  ASP E N   1 
ATOM   6860 C CA  . ASP E 5 62  ? 127.960 178.369 121.446 1.00 43.18 ? 62  ASP E CA  1 
ATOM   6861 C C   . ASP E 5 62  ? 126.753 179.296 121.358 1.00 41.81 ? 62  ASP E C   1 
ATOM   6862 O O   . ASP E 5 62  ? 126.230 179.741 122.386 1.00 44.51 ? 62  ASP E O   1 
ATOM   6863 C CB  . ASP E 5 62  ? 129.257 179.172 121.346 1.00 45.86 ? 62  ASP E CB  1 
ATOM   6864 C CG  . ASP E 5 62  ? 129.402 179.889 120.017 1.00 52.80 ? 62  ASP E CG  1 
ATOM   6865 O OD1 . ASP E 5 62  ? 128.902 179.362 119.001 1.00 52.38 ? 62  ASP E OD1 1 
ATOM   6866 O OD2 . ASP E 5 62  ? 130.008 180.980 119.989 1.00 50.35 ? 62  ASP E OD2 1 
ATOM   6867 N N   . THR E 5 63  ? 126.305 179.610 120.139 1.00 37.71 ? 63  THR E N   1 
ATOM   6868 C CA  . THR E 5 63  ? 125.187 180.534 119.972 1.00 39.87 ? 63  THR E CA  1 
ATOM   6869 C C   . THR E 5 63  ? 123.900 179.963 120.552 1.00 46.00 ? 63  THR E C   1 
ATOM   6870 O O   . THR E 5 63  ? 123.134 180.679 121.208 1.00 56.18 ? 63  THR E O   1 
ATOM   6871 C CB  . THR E 5 63  ? 124.999 180.858 118.490 1.00 39.59 ? 63  THR E CB  1 
ATOM   6872 O OG1 . THR E 5 63  ? 126.268 181.156 117.897 1.00 47.97 ? 63  THR E OG1 1 
ATOM   6873 C CG2 . THR E 5 63  ? 124.069 182.049 118.310 1.00 42.64 ? 63  THR E CG2 1 
ATOM   6874 N N   . VAL E 5 64  ? 123.647 178.675 120.319 1.00 35.80 ? 64  VAL E N   1 
ATOM   6875 C CA  . VAL E 5 64  ? 122.375 178.071 120.712 1.00 25.32 ? 64  VAL E CA  1 
ATOM   6876 C C   . VAL E 5 64  ? 122.411 177.580 122.159 1.00 28.30 ? 64  VAL E C   1 
ATOM   6877 O O   . VAL E 5 64  ? 121.360 177.403 122.785 1.00 38.37 ? 64  VAL E O   1 
ATOM   6878 C CB  . VAL E 5 64  ? 121.990 176.942 119.731 1.00 35.66 ? 64  VAL E CB  1 
ATOM   6879 C CG1 . VAL E 5 64  ? 121.708 177.516 118.351 1.00 36.00 ? 64  VAL E CG1 1 
ATOM   6880 C CG2 . VAL E 5 64  ? 123.071 175.849 119.629 1.00 36.68 ? 64  VAL E CG2 1 
ATOM   6881 N N   . LYS E 5 65  ? 123.603 177.333 122.706 1.00 34.83 ? 65  LYS E N   1 
ATOM   6882 C CA  . LYS E 5 65  ? 123.719 176.664 123.998 1.00 34.38 ? 65  LYS E CA  1 
ATOM   6883 C C   . LYS E 5 65  ? 123.132 177.511 125.121 1.00 43.58 ? 65  LYS E C   1 
ATOM   6884 O O   . LYS E 5 65  ? 123.228 178.741 125.113 1.00 40.99 ? 65  LYS E O   1 
ATOM   6885 C CB  . LYS E 5 65  ? 125.185 176.349 124.297 1.00 33.73 ? 65  LYS E CB  1 
ATOM   6886 C CG  . LYS E 5 65  ? 125.404 175.664 125.644 1.00 33.59 ? 65  LYS E CG  1 
ATOM   6887 C CD  . LYS E 5 65  ? 126.525 174.614 125.664 1.00 33.76 ? 65  LYS E CD  1 
ATOM   6888 C CE  . LYS E 5 65  ? 127.848 175.050 125.026 1.00 40.12 ? 65  LYS E CE  1 
ATOM   6889 N NZ  . LYS E 5 65  ? 128.804 173.910 124.996 1.00 41.78 ? 65  LYS E NZ  1 
ATOM   6890 N N   . GLY E 5 66  ? 122.508 176.836 126.090 1.00 42.27 ? 66  GLY E N   1 
ATOM   6891 C CA  . GLY E 5 66  ? 121.765 177.494 127.142 1.00 37.09 ? 66  GLY E CA  1 
ATOM   6892 C C   . GLY E 5 66  ? 120.368 177.911 126.750 1.00 38.05 ? 66  GLY E C   1 
ATOM   6893 O O   . GLY E 5 66  ? 119.598 178.332 127.623 1.00 39.04 ? 66  GLY E O   1 
ATOM   6894 N N   . ARG E 5 67  ? 120.018 177.801 125.467 1.00 40.25 ? 67  ARG E N   1 
ATOM   6895 C CA  . ARG E 5 67  ? 118.788 178.335 124.912 1.00 35.96 ? 67  ARG E CA  1 
ATOM   6896 C C   . ARG E 5 67  ? 118.043 177.335 124.035 1.00 40.34 ? 67  ARG E C   1 
ATOM   6897 O O   . ARG E 5 67  ? 116.825 177.467 123.881 1.00 41.43 ? 67  ARG E O   1 
ATOM   6898 C CB  . ARG E 5 67  ? 119.124 179.602 124.113 1.00 33.01 ? 67  ARG E CB  1 
ATOM   6899 C CG  . ARG E 5 67  ? 117.996 180.229 123.347 1.00 37.71 ? 67  ARG E CG  1 
ATOM   6900 C CD  . ARG E 5 67  ? 118.393 181.592 122.787 1.00 37.92 ? 67  ARG E CD  1 
ATOM   6901 N NE  . ARG E 5 67  ? 119.659 181.562 122.056 1.00 40.43 ? 67  ARG E NE  1 
ATOM   6902 C CZ  . ARG E 5 67  ? 119.798 181.515 120.735 1.00 44.98 ? 67  ARG E CZ  1 
ATOM   6903 N NH1 . ARG E 5 67  ? 118.766 181.345 119.923 1.00 39.12 ? 67  ARG E NH1 1 
ATOM   6904 N NH2 . ARG E 5 67  ? 121.016 181.612 120.211 1.00 50.24 ? 67  ARG E NH2 1 
ATOM   6905 N N   . PHE E 5 68  ? 118.742 176.349 123.465 1.00 35.89 ? 68  PHE E N   1 
ATOM   6906 C CA  . PHE E 5 68  ? 118.164 175.255 122.693 1.00 31.65 ? 68  PHE E CA  1 
ATOM   6907 C C   . PHE E 5 68  ? 118.408 173.962 123.454 1.00 34.96 ? 68  PHE E C   1 
ATOM   6908 O O   . PHE E 5 68  ? 119.424 173.834 124.143 1.00 29.49 ? 68  PHE E O   1 
ATOM   6909 C CB  . PHE E 5 68  ? 118.808 175.136 121.301 1.00 27.64 ? 68  PHE E CB  1 
ATOM   6910 C CG  . PHE E 5 68  ? 118.311 176.128 120.269 1.00 22.00 ? 68  PHE E CG  1 
ATOM   6911 C CD1 . PHE E 5 68  ? 117.614 177.278 120.608 1.00 31.13 ? 68  PHE E CD1 1 
ATOM   6912 C CD2 . PHE E 5 68  ? 118.567 175.890 118.932 1.00 25.18 ? 68  PHE E CD2 1 
ATOM   6913 C CE1 . PHE E 5 68  ? 117.183 178.154 119.632 1.00 32.90 ? 68  PHE E CE1 1 
ATOM   6914 C CE2 . PHE E 5 68  ? 118.139 176.762 117.960 1.00 31.55 ? 68  PHE E CE2 1 
ATOM   6915 C CZ  . PHE E 5 68  ? 117.446 177.893 118.309 1.00 36.36 ? 68  PHE E CZ  1 
ATOM   6916 N N   . THR E 5 69  ? 117.483 173.010 123.331 1.00 30.59 ? 69  THR E N   1 
ATOM   6917 C CA  . THR E 5 69  ? 117.621 171.684 123.923 1.00 24.69 ? 69  THR E CA  1 
ATOM   6918 C C   . THR E 5 69  ? 117.221 170.632 122.899 1.00 31.78 ? 69  THR E C   1 
ATOM   6919 O O   . THR E 5 69  ? 116.174 170.758 122.255 1.00 28.00 ? 69  THR E O   1 
ATOM   6920 C CB  . THR E 5 69  ? 116.760 171.553 125.183 1.00 28.19 ? 69  THR E CB  1 
ATOM   6921 O OG1 . THR E 5 69  ? 116.981 172.685 126.033 1.00 35.26 ? 69  THR E OG1 1 
ATOM   6922 C CG2 . THR E 5 69  ? 117.110 170.287 125.950 1.00 27.66 ? 69  THR E CG2 1 
ATOM   6923 N N   . ILE E 5 70  ? 118.048 169.594 122.763 1.00 31.81 ? 70  ILE E N   1 
ATOM   6924 C CA  . ILE E 5 70  ? 117.833 168.503 121.814 1.00 26.61 ? 70  ILE E CA  1 
ATOM   6925 C C   . ILE E 5 70  ? 117.556 167.234 122.609 1.00 27.75 ? 70  ILE E C   1 
ATOM   6926 O O   . ILE E 5 70  ? 118.233 166.956 123.606 1.00 33.96 ? 70  ILE E O   1 
ATOM   6927 C CB  . ILE E 5 70  ? 119.037 168.325 120.868 1.00 24.39 ? 70  ILE E CB  1 
ATOM   6928 C CG1 . ILE E 5 70  ? 118.676 167.401 119.697 1.00 25.26 ? 70  ILE E CG1 1 
ATOM   6929 C CG2 . ILE E 5 70  ? 120.246 167.765 121.604 1.00 26.45 ? 70  ILE E CG2 1 
ATOM   6930 C CD1 . ILE E 5 70  ? 119.832 167.077 118.785 1.00 26.16 ? 70  ILE E CD1 1 
ATOM   6931 N N   . SER E 5 71  ? 116.544 166.482 122.182 1.00 24.40 ? 71  SER E N   1 
ATOM   6932 C CA  . SER E 5 71  ? 116.159 165.232 122.819 1.00 20.53 ? 71  SER E CA  1 
ATOM   6933 C C   . SER E 5 71  ? 115.667 164.257 121.761 1.00 31.19 ? 71  SER E C   1 
ATOM   6934 O O   . SER E 5 71  ? 115.199 164.665 120.695 1.00 32.93 ? 71  SER E O   1 
ATOM   6935 C CB  . SER E 5 71  ? 115.064 165.452 123.862 1.00 27.55 ? 71  SER E CB  1 
ATOM   6936 O OG  . SER E 5 71  ? 115.433 166.463 124.781 1.00 31.99 ? 71  SER E OG  1 
ATOM   6937 N N   . ARG E 5 72  ? 115.774 162.965 122.069 1.00 34.50 ? 72  ARG E N   1 
ATOM   6938 C CA  . ARG E 5 72  ? 115.332 161.888 121.190 1.00 27.16 ? 72  ARG E CA  1 
ATOM   6939 C C   . ARG E 5 72  ? 114.429 160.941 121.965 1.00 26.88 ? 72  ARG E C   1 
ATOM   6940 O O   . ARG E 5 72  ? 114.703 160.631 123.129 1.00 34.75 ? 72  ARG E O   1 
ATOM   6941 C CB  . ARG E 5 72  ? 116.532 161.134 120.598 1.00 28.86 ? 72  ARG E CB  1 
ATOM   6942 C CG  . ARG E 5 72  ? 117.223 160.153 121.542 1.00 30.47 ? 72  ARG E CG  1 
ATOM   6943 C CD  . ARG E 5 72  ? 118.544 159.657 120.979 1.00 22.32 ? 72  ARG E CD  1 
ATOM   6944 N NE  . ARG E 5 72  ? 118.406 159.118 119.632 1.00 24.86 ? 72  ARG E NE  1 
ATOM   6945 C CZ  . ARG E 5 72  ? 119.411 158.873 118.799 1.00 24.74 ? 72  ARG E CZ  1 
ATOM   6946 N NH1 . ARG E 5 72  ? 120.671 159.099 119.137 1.00 25.21 ? 72  ARG E NH1 1 
ATOM   6947 N NH2 . ARG E 5 72  ? 119.144 158.388 117.591 1.00 22.65 ? 72  ARG E NH2 1 
ATOM   6948 N N   . ASP E 5 73  ? 113.350 160.494 121.319 1.00 29.43 ? 73  ASP E N   1 
ATOM   6949 C CA  . ASP E 5 73  ? 112.459 159.460 121.847 1.00 40.69 ? 73  ASP E CA  1 
ATOM   6950 C C   . ASP E 5 73  ? 112.670 158.208 121.004 1.00 40.30 ? 73  ASP E C   1 
ATOM   6951 O O   . ASP E 5 73  ? 112.017 158.023 119.975 1.00 44.30 ? 73  ASP E O   1 
ATOM   6952 C CB  . ASP E 5 73  ? 111.006 159.928 121.811 1.00 44.41 ? 73  ASP E CB  1 
ATOM   6953 C CG  . ASP E 5 73  ? 110.061 158.982 122.531 1.00 50.84 ? 73  ASP E CG  1 
ATOM   6954 O OD1 . ASP E 5 73  ? 110.535 158.091 123.264 1.00 45.95 ? 73  ASP E OD1 1 
ATOM   6955 O OD2 . ASP E 5 73  ? 108.833 159.136 122.367 1.00 51.39 ? 73  ASP E OD2 1 
ATOM   6956 N N   . ASP E 5 74  ? 113.586 157.346 121.447 1.00 39.33 ? 74  ASP E N   1 
ATOM   6957 C CA  . ASP E 5 74  ? 114.008 156.182 120.673 1.00 38.57 ? 74  ASP E CA  1 
ATOM   6958 C C   . ASP E 5 74  ? 112.871 155.198 120.396 1.00 48.16 ? 74  ASP E C   1 
ATOM   6959 O O   . ASP E 5 74  ? 112.769 154.717 119.260 1.00 50.18 ? 74  ASP E O   1 
ATOM   6960 C CB  . ASP E 5 74  ? 115.167 155.463 121.379 1.00 40.02 ? 74  ASP E CB  1 
ATOM   6961 C CG  . ASP E 5 74  ? 116.520 156.125 121.140 1.00 43.04 ? 74  ASP E CG  1 
ATOM   6962 O OD1 . ASP E 5 74  ? 116.642 156.999 120.258 1.00 46.41 ? 74  ASP E OD1 1 
ATOM   6963 O OD2 . ASP E 5 74  ? 117.479 155.759 121.851 1.00 47.03 ? 74  ASP E OD2 1 
ATOM   6964 N N   . PRO E 5 75  ? 112.021 154.838 121.373 1.00 54.48 ? 75  PRO E N   1 
ATOM   6965 C CA  . PRO E 5 75  ? 110.874 153.973 121.028 1.00 50.16 ? 75  PRO E CA  1 
ATOM   6966 C C   . PRO E 5 75  ? 109.934 154.575 119.997 1.00 46.69 ? 75  PRO E C   1 
ATOM   6967 O O   . PRO E 5 75  ? 109.438 153.851 119.125 1.00 47.17 ? 75  PRO E O   1 
ATOM   6968 C CB  . PRO E 5 75  ? 110.174 153.771 122.378 1.00 48.69 ? 75  PRO E CB  1 
ATOM   6969 C CG  . PRO E 5 75  ? 111.234 153.948 123.373 1.00 50.29 ? 75  PRO E CG  1 
ATOM   6970 C CD  . PRO E 5 75  ? 112.102 155.035 122.833 1.00 50.22 ? 75  PRO E CD  1 
ATOM   6971 N N   . LYS E 5 76  ? 109.677 155.882 120.069 1.00 42.74 ? 76  LYS E N   1 
ATOM   6972 C CA  . LYS E 5 76  ? 108.790 156.534 119.112 1.00 42.46 ? 76  LYS E CA  1 
ATOM   6973 C C   . LYS E 5 76  ? 109.479 156.891 117.798 1.00 51.10 ? 76  LYS E C   1 
ATOM   6974 O O   . LYS E 5 76  ? 108.785 157.290 116.857 1.00 53.61 ? 76  LYS E O   1 
ATOM   6975 C CB  . LYS E 5 76  ? 108.197 157.799 119.733 1.00 39.12 ? 76  LYS E CB  1 
ATOM   6976 N N   . ASN E 5 77  ? 110.809 156.759 117.710 1.00 44.71 ? 77  ASN E N   1 
ATOM   6977 C CA  . ASN E 5 77  ? 111.572 157.112 116.508 1.00 34.11 ? 77  ASN E CA  1 
ATOM   6978 C C   . ASN E 5 77  ? 111.355 158.576 116.127 1.00 35.13 ? 77  ASN E C   1 
ATOM   6979 O O   . ASN E 5 77  ? 110.932 158.890 115.013 1.00 37.99 ? 77  ASN E O   1 
ATOM   6980 C CB  . ASN E 5 77  ? 111.231 156.187 115.335 1.00 35.75 ? 77  ASN E CB  1 
ATOM   6981 C CG  . ASN E 5 77  ? 111.834 154.809 115.487 1.00 44.00 ? 77  ASN E CG  1 
ATOM   6982 O OD1 . ASN E 5 77  ? 112.268 154.423 116.571 1.00 37.20 ? 77  ASN E OD1 1 
ATOM   6983 N ND2 . ASN E 5 77  ? 111.869 154.058 114.394 1.00 42.60 ? 77  ASN E ND2 1 
ATOM   6984 N N   . THR E 5 78  ? 111.615 159.478 117.072 1.00 30.16 ? 78  THR E N   1 
ATOM   6985 C CA  . THR E 5 78  ? 111.502 160.911 116.843 1.00 32.28 ? 78  THR E CA  1 
ATOM   6986 C C   . THR E 5 78  ? 112.624 161.634 117.574 1.00 39.46 ? 78  THR E C   1 
ATOM   6987 O O   . THR E 5 78  ? 113.019 161.245 118.676 1.00 46.81 ? 78  THR E O   1 
ATOM   6988 C CB  . THR E 5 78  ? 110.134 161.444 117.309 1.00 35.94 ? 78  THR E CB  1 
ATOM   6989 O OG1 . THR E 5 78  ? 109.088 160.759 116.609 1.00 41.17 ? 78  THR E OG1 1 
ATOM   6990 C CG2 . THR E 5 78  ? 110.006 162.931 117.033 1.00 33.85 ? 78  THR E CG2 1 
ATOM   6991 N N   . LEU E 5 79  ? 113.131 162.690 116.939 1.00 31.52 ? 79  LEU E N   1 
ATOM   6992 C CA  . LEU E 5 79  ? 114.119 163.596 117.510 1.00 24.45 ? 79  LEU E CA  1 
ATOM   6993 C C   . LEU E 5 79  ? 113.507 164.983 117.583 1.00 32.02 ? 79  LEU E C   1 
ATOM   6994 O O   . LEU E 5 79  ? 112.967 165.463 116.586 1.00 26.83 ? 79  LEU E O   1 
ATOM   6995 C CB  . LEU E 5 79  ? 115.390 163.628 116.657 1.00 18.57 ? 79  LEU E CB  1 
ATOM   6996 C CG  . LEU E 5 79  ? 116.540 164.537 117.092 1.00 31.08 ? 79  LEU E CG  1 
ATOM   6997 C CD1 . LEU E 5 79  ? 117.246 163.908 118.230 1.00 32.20 ? 79  LEU E CD1 1 
ATOM   6998 C CD2 . LEU E 5 79  ? 117.504 164.786 115.955 1.00 22.63 ? 79  LEU E CD2 1 
ATOM   6999 N N   . PHE E 5 80  ? 113.629 165.634 118.746 1.00 28.14 ? 80  PHE E N   1 
ATOM   7000 C CA  . PHE E 5 80  ? 113.061 166.955 118.994 1.00 27.21 ? 80  PHE E CA  1 
ATOM   7001 C C   . PHE E 5 80  ? 114.165 167.975 119.219 1.00 28.93 ? 80  PHE E C   1 
ATOM   7002 O O   . PHE E 5 80  ? 115.248 167.635 119.704 1.00 29.05 ? 80  PHE E O   1 
ATOM   7003 C CB  . PHE E 5 80  ? 112.140 166.984 120.226 1.00 31.41 ? 80  PHE E CB  1 
ATOM   7004 C CG  . PHE E 5 80  ? 111.290 165.765 120.392 1.00 29.98 ? 80  PHE E CG  1 
ATOM   7005 C CD1 . PHE E 5 80  ? 111.742 164.689 121.129 1.00 30.51 ? 80  PHE E CD1 1 
ATOM   7006 C CD2 . PHE E 5 80  ? 110.027 165.705 119.833 1.00 29.72 ? 80  PHE E CD2 1 
ATOM   7007 C CE1 . PHE E 5 80  ? 110.963 163.573 121.291 1.00 34.88 ? 80  PHE E CE1 1 
ATOM   7008 C CE2 . PHE E 5 80  ? 109.241 164.589 119.994 1.00 31.23 ? 80  PHE E CE2 1 
ATOM   7009 C CZ  . PHE E 5 80  ? 109.710 163.520 120.724 1.00 35.19 ? 80  PHE E CZ  1 
ATOM   7010 N N   . LEU E 5 81  ? 113.882 169.222 118.850 1.00 28.78 ? 81  LEU E N   1 
ATOM   7011 C CA  . LEU E 5 81  ? 114.653 170.384 119.269 1.00 27.22 ? 81  LEU E CA  1 
ATOM   7012 C C   . LEU E 5 81  ? 113.713 171.360 119.956 1.00 36.84 ? 81  LEU E C   1 
ATOM   7013 O O   . LEU E 5 81  ? 112.790 171.883 119.323 1.00 34.09 ? 81  LEU E O   1 
ATOM   7014 C CB  . LEU E 5 81  ? 115.340 171.066 118.082 1.00 29.98 ? 81  LEU E CB  1 
ATOM   7015 C CG  . LEU E 5 81  ? 116.443 172.076 118.415 1.00 14.51 ? 81  LEU E CG  1 
ATOM   7016 C CD1 . LEU E 5 81  ? 117.730 171.386 118.823 1.00 21.28 ? 81  LEU E CD1 1 
ATOM   7017 C CD2 . LEU E 5 81  ? 116.682 172.995 117.239 1.00 15.06 ? 81  LEU E CD2 1 
ATOM   7018 N N   . GLN E 5 82  ? 113.951 171.606 121.241 1.00 39.22 ? 82  GLN E N   1 
ATOM   7019 C CA  . GLN E 5 82  ? 113.186 172.567 122.026 1.00 32.82 ? 82  GLN E CA  1 
ATOM   7020 C C   . GLN E 5 82  ? 113.937 173.890 122.018 1.00 28.54 ? 82  GLN E C   1 
ATOM   7021 O O   . GLN E 5 82  ? 115.069 173.963 122.508 1.00 25.07 ? 82  GLN E O   1 
ATOM   7022 C CB  . GLN E 5 82  ? 112.982 172.074 123.459 1.00 35.80 ? 82  GLN E CB  1 
ATOM   7023 C CG  . GLN E 5 82  ? 111.523 171.908 123.864 1.00 39.00 ? 82  GLN E CG  1 
ATOM   7024 C CD  . GLN E 5 82  ? 110.780 173.227 123.953 1.00 44.72 ? 82  GLN E CD  1 
ATOM   7025 O OE1 . GLN E 5 82  ? 111.383 174.280 124.148 1.00 42.87 ? 82  GLN E OE1 1 
ATOM   7026 N NE2 . GLN E 5 82  ? 109.461 173.174 123.808 1.00 40.01 ? 82  GLN E NE2 1 
ATOM   7027 N N   . MET E 5 83  ? 113.305 174.923 121.464 1.00 32.01 ? 83  MET E N   1 
ATOM   7028 C CA  . MET E 5 83  ? 113.889 176.252 121.339 1.00 36.14 ? 83  MET E CA  1 
ATOM   7029 C C   . MET E 5 83  ? 113.085 177.218 122.193 1.00 39.35 ? 83  MET E C   1 
ATOM   7030 O O   . MET E 5 83  ? 111.851 177.168 122.194 1.00 38.19 ? 83  MET E O   1 
ATOM   7031 C CB  . MET E 5 83  ? 113.896 176.733 119.884 1.00 43.84 ? 83  MET E CB  1 
ATOM   7032 C CG  . MET E 5 83  ? 114.556 175.784 118.890 1.00 40.02 ? 83  MET E CG  1 
ATOM   7033 S SD  . MET E 5 83  ? 114.425 176.346 117.181 1.00 34.42 ? 83  MET E SD  1 
ATOM   7034 C CE  . MET E 5 83  ? 112.671 176.191 116.873 1.00 39.58 ? 83  MET E CE  1 
ATOM   7035 N N   . THR E 5 84  ? 113.788 178.082 122.921 1.00 47.51 ? 84  THR E N   1 
ATOM   7036 C CA  . THR E 5 84  ? 113.185 179.114 123.749 1.00 44.28 ? 84  THR E CA  1 
ATOM   7037 C C   . THR E 5 84  ? 113.864 180.441 123.449 1.00 44.59 ? 84  THR E C   1 
ATOM   7038 O O   . THR E 5 84  ? 115.009 180.479 122.995 1.00 43.01 ? 84  THR E O   1 
ATOM   7039 C CB  . THR E 5 84  ? 113.308 178.787 125.245 1.00 42.85 ? 84  THR E CB  1 
ATOM   7040 O OG1 . THR E 5 84  ? 114.607 178.248 125.516 1.00 44.74 ? 84  THR E OG1 1 
ATOM   7041 C CG2 . THR E 5 84  ? 112.244 177.787 125.667 1.00 41.13 ? 84  THR E CG2 1 
ATOM   7042 N N   . SER E 5 85  ? 113.138 181.532 123.712 1.00 46.34 ? 85  SER E N   1 
ATOM   7043 C CA  . SER E 5 85  ? 113.637 182.905 123.545 1.00 46.65 ? 85  SER E CA  1 
ATOM   7044 C C   . SER E 5 85  ? 114.199 183.124 122.142 1.00 46.07 ? 85  SER E C   1 
ATOM   7045 O O   . SER E 5 85  ? 115.329 183.584 121.969 1.00 44.04 ? 85  SER E O   1 
ATOM   7046 C CB  . SER E 5 85  ? 114.677 183.269 124.611 1.00 50.29 ? 85  SER E CB  1 
ATOM   7047 O OG  . SER E 5 85  ? 115.713 182.311 124.717 1.00 51.86 ? 85  SER E OG  1 
ATOM   7048 N N   . LEU E 5 86  ? 113.410 182.758 121.135 1.00 46.47 ? 86  LEU E N   1 
ATOM   7049 C CA  . LEU E 5 86  ? 113.877 182.805 119.758 1.00 43.08 ? 86  LEU E CA  1 
ATOM   7050 C C   . LEU E 5 86  ? 114.176 184.239 119.339 1.00 45.50 ? 86  LEU E C   1 
ATOM   7051 O O   . LEU E 5 86  ? 113.516 185.186 119.774 1.00 51.62 ? 86  LEU E O   1 
ATOM   7052 C CB  . LEU E 5 86  ? 112.831 182.184 118.828 1.00 40.29 ? 86  LEU E CB  1 
ATOM   7053 C CG  . LEU E 5 86  ? 112.748 180.653 118.740 1.00 45.29 ? 86  LEU E CG  1 
ATOM   7054 C CD1 . LEU E 5 86  ? 111.679 180.259 117.745 1.00 48.69 ? 86  LEU E CD1 1 
ATOM   7055 C CD2 . LEU E 5 86  ? 114.063 180.007 118.343 1.00 42.36 ? 86  LEU E CD2 1 
ATOM   7056 N N   . ARG E 5 87  ? 115.186 184.381 118.486 1.00 43.89 ? 87  ARG E N   1 
ATOM   7057 C CA  . ARG E 5 87  ? 115.766 185.657 118.107 1.00 41.01 ? 87  ARG E CA  1 
ATOM   7058 C C   . ARG E 5 87  ? 115.815 185.702 116.585 1.00 46.25 ? 87  ARG E C   1 
ATOM   7059 O O   . ARG E 5 87  ? 115.695 184.672 115.921 1.00 52.52 ? 87  ARG E O   1 
ATOM   7060 C CB  . ARG E 5 87  ? 117.160 185.805 118.758 1.00 41.35 ? 87  ARG E CB  1 
ATOM   7061 C CG  . ARG E 5 87  ? 118.021 186.968 118.300 1.00 45.90 ? 87  ARG E CG  1 
ATOM   7062 C CD  . ARG E 5 87  ? 119.034 187.409 119.358 1.00 49.75 ? 87  ARG E CD  1 
ATOM   7063 N NE  . ARG E 5 87  ? 120.027 186.381 119.670 1.00 50.66 ? 87  ARG E NE  1 
ATOM   7064 C CZ  . ARG E 5 87  ? 119.951 185.481 120.646 1.00 49.04 ? 87  ARG E CZ  1 
ATOM   7065 N NH1 . ARG E 5 87  ? 118.932 185.441 121.493 1.00 48.83 ? 87  ARG E NH1 1 
ATOM   7066 N NH2 . ARG E 5 87  ? 120.936 184.600 120.787 1.00 46.38 ? 87  ARG E NH2 1 
ATOM   7067 N N   . SER E 5 88  ? 115.955 186.910 116.027 1.00 47.17 ? 88  SER E N   1 
ATOM   7068 C CA  . SER E 5 88  ? 115.917 187.076 114.574 1.00 40.40 ? 88  SER E CA  1 
ATOM   7069 C C   . SER E 5 88  ? 117.021 186.294 113.867 1.00 36.31 ? 88  SER E C   1 
ATOM   7070 O O   . SER E 5 88  ? 116.876 185.954 112.688 1.00 39.00 ? 88  SER E O   1 
ATOM   7071 C CB  . SER E 5 88  ? 116.021 188.558 114.220 1.00 43.27 ? 88  SER E CB  1 
ATOM   7072 O OG  . SER E 5 88  ? 114.880 189.265 114.670 1.00 44.14 ? 88  SER E OG  1 
ATOM   7073 N N   . GLU E 5 89  ? 118.124 186.000 114.559 1.00 40.50 ? 89  GLU E N   1 
ATOM   7074 C CA  . GLU E 5 89  ? 119.167 185.166 113.971 1.00 45.30 ? 89  GLU E CA  1 
ATOM   7075 C C   . GLU E 5 89  ? 118.665 183.752 113.698 1.00 41.63 ? 89  GLU E C   1 
ATOM   7076 O O   . GLU E 5 89  ? 119.139 183.087 112.771 1.00 37.55 ? 89  GLU E O   1 
ATOM   7077 C CB  . GLU E 5 89  ? 120.383 185.130 114.895 1.00 42.57 ? 89  GLU E CB  1 
ATOM   7078 N N   . ASP E 5 90  ? 117.707 183.272 114.496 1.00 37.73 ? 90  ASP E N   1 
ATOM   7079 C CA  . ASP E 5 90  ? 117.325 181.863 114.440 1.00 36.51 ? 90  ASP E CA  1 
ATOM   7080 C C   . ASP E 5 90  ? 116.525 181.518 113.188 1.00 42.12 ? 90  ASP E C   1 
ATOM   7081 O O   . ASP E 5 90  ? 116.265 180.336 112.941 1.00 48.85 ? 90  ASP E O   1 
ATOM   7082 C CB  . ASP E 5 90  ? 116.514 181.493 115.684 1.00 35.56 ? 90  ASP E CB  1 
ATOM   7083 C CG  . ASP E 5 90  ? 117.382 181.296 116.919 1.00 43.50 ? 90  ASP E CG  1 
ATOM   7084 O OD1 . ASP E 5 90  ? 118.625 181.335 116.809 1.00 46.11 ? 90  ASP E OD1 1 
ATOM   7085 O OD2 . ASP E 5 90  ? 116.822 181.119 118.019 1.00 46.00 ? 90  ASP E OD2 1 
ATOM   7086 N N   . THR E 5 91  ? 116.089 182.514 112.413 1.00 39.19 ? 91  THR E N   1 
ATOM   7087 C CA  . THR E 5 91  ? 115.369 182.228 111.178 1.00 35.23 ? 91  THR E CA  1 
ATOM   7088 C C   . THR E 5 91  ? 116.253 181.437 110.222 1.00 35.06 ? 91  THR E C   1 
ATOM   7089 O O   . THR E 5 91  ? 117.357 181.860 109.871 1.00 48.79 ? 91  THR E O   1 
ATOM   7090 C CB  . THR E 5 91  ? 114.883 183.524 110.512 1.00 33.64 ? 91  THR E CB  1 
ATOM   7091 O OG1 . THR E 5 91  ? 114.154 183.202 109.325 1.00 39.68 ? 91  THR E OG1 1 
ATOM   7092 C CG2 . THR E 5 91  ? 116.034 184.463 110.123 1.00 43.03 ? 91  THR E CG2 1 
ATOM   7093 N N   . ALA E 5 92  ? 115.769 180.262 109.819 1.00 27.62 ? 92  ALA E N   1 
ATOM   7094 C CA  . ALA E 5 92  ? 116.567 179.331 109.032 1.00 32.39 ? 92  ALA E CA  1 
ATOM   7095 C C   . ALA E 5 92  ? 115.721 178.136 108.615 1.00 36.83 ? 92  ALA E C   1 
ATOM   7096 O O   . ALA E 5 92  ? 114.545 178.051 108.981 1.00 39.65 ? 92  ALA E O   1 
ATOM   7097 C CB  . ALA E 5 92  ? 117.787 178.861 109.833 1.00 30.71 ? 92  ALA E CB  1 
ATOM   7098 N N   . MET E 5 93  ? 116.307 177.219 107.845 1.00 35.45 ? 93  MET E N   1 
ATOM   7099 C CA  . MET E 5 93  ? 115.715 175.922 107.538 1.00 29.29 ? 93  MET E CA  1 
ATOM   7100 C C   . MET E 5 93  ? 116.501 174.867 108.296 1.00 33.45 ? 93  MET E C   1 
ATOM   7101 O O   . MET E 5 93  ? 117.692 174.677 108.035 1.00 38.69 ? 93  MET E O   1 
ATOM   7102 C CB  . MET E 5 93  ? 115.749 175.631 106.031 1.00 27.64 ? 93  MET E CB  1 
ATOM   7103 C CG  . MET E 5 93  ? 114.735 174.587 105.551 1.00 37.64 ? 93  MET E CG  1 
ATOM   7104 S SD  . MET E 5 93  ? 114.095 174.952 103.905 1.00 61.71 ? 93  MET E SD  1 
ATOM   7105 C CE  . MET E 5 93  ? 113.267 173.416 103.494 1.00 39.62 ? 93  MET E CE  1 
ATOM   7106 N N   . TYR E 5 94  ? 115.835 174.172 109.212 1.00 26.94 ? 94  TYR E N   1 
ATOM   7107 C CA  . TYR E 5 94  ? 116.482 173.253 110.137 1.00 20.71 ? 94  TYR E CA  1 
ATOM   7108 C C   . TYR E 5 94  ? 116.432 171.845 109.569 1.00 21.63 ? 94  TYR E C   1 
ATOM   7109 O O   . TYR E 5 94  ? 115.348 171.333 109.279 1.00 33.29 ? 94  TYR E O   1 
ATOM   7110 C CB  . TYR E 5 94  ? 115.795 173.287 111.503 1.00 23.31 ? 94  TYR E CB  1 
ATOM   7111 C CG  . TYR E 5 94  ? 116.100 174.523 112.314 1.00 26.37 ? 94  TYR E CG  1 
ATOM   7112 C CD1 . TYR E 5 94  ? 115.469 175.727 112.039 1.00 29.44 ? 94  TYR E CD1 1 
ATOM   7113 C CD2 . TYR E 5 94  ? 117.005 174.482 113.362 1.00 20.40 ? 94  TYR E CD2 1 
ATOM   7114 C CE1 . TYR E 5 94  ? 115.742 176.856 112.775 1.00 24.91 ? 94  TYR E CE1 1 
ATOM   7115 C CE2 . TYR E 5 94  ? 117.280 175.606 114.105 1.00 26.91 ? 94  TYR E CE2 1 
ATOM   7116 C CZ  . TYR E 5 94  ? 116.647 176.789 113.808 1.00 26.69 ? 94  TYR E CZ  1 
ATOM   7117 O OH  . TYR E 5 94  ? 116.920 177.913 114.548 1.00 27.74 ? 94  TYR E OH  1 
ATOM   7118 N N   . TYR E 5 95  ? 117.600 171.218 109.439 1.00 14.91 ? 95  TYR E N   1 
ATOM   7119 C CA  . TYR E 5 95  ? 117.740 169.887 108.866 1.00 9.69  ? 95  TYR E CA  1 
ATOM   7120 C C   . TYR E 5 95  ? 118.041 168.883 109.965 1.00 10.69 ? 95  TYR E C   1 
ATOM   7121 O O   . TYR E 5 95  ? 118.818 169.165 110.881 1.00 29.70 ? 95  TYR E O   1 
ATOM   7122 C CB  . TYR E 5 95  ? 118.858 169.842 107.821 1.00 15.76 ? 95  TYR E CB  1 
ATOM   7123 C CG  . TYR E 5 95  ? 118.627 170.726 106.623 1.00 12.76 ? 95  TYR E CG  1 
ATOM   7124 C CD1 . TYR E 5 95  ? 117.736 170.361 105.630 1.00 22.67 ? 95  TYR E CD1 1 
ATOM   7125 C CD2 . TYR E 5 95  ? 119.303 171.927 106.483 1.00 16.47 ? 95  TYR E CD2 1 
ATOM   7126 C CE1 . TYR E 5 95  ? 117.522 171.166 104.535 1.00 25.83 ? 95  TYR E CE1 1 
ATOM   7127 C CE2 . TYR E 5 95  ? 119.095 172.738 105.392 1.00 17.88 ? 95  TYR E CE2 1 
ATOM   7128 C CZ  . TYR E 5 95  ? 118.203 172.353 104.421 1.00 26.81 ? 95  TYR E CZ  1 
ATOM   7129 O OH  . TYR E 5 95  ? 117.991 173.157 103.327 1.00 36.09 ? 95  TYR E OH  1 
ATOM   7130 N N   . CYS E 5 96  ? 117.424 167.711 109.856 1.00 15.63 ? 96  CYS E N   1 
ATOM   7131 C CA  . CYS E 5 96  ? 117.654 166.591 110.755 1.00 17.04 ? 96  CYS E CA  1 
ATOM   7132 C C   . CYS E 5 96  ? 118.544 165.595 110.025 1.00 19.98 ? 96  CYS E C   1 
ATOM   7133 O O   . CYS E 5 96  ? 118.188 165.124 108.941 1.00 45.26 ? 96  CYS E O   1 
ATOM   7134 C CB  . CYS E 5 96  ? 116.328 165.943 111.170 1.00 23.64 ? 96  CYS E CB  1 
ATOM   7135 S SG  . CYS E 5 96  ? 116.389 165.081 112.755 1.00 37.57 ? 96  CYS E SG  1 
ATOM   7136 N N   . VAL E 5 97  ? 119.694 165.284 110.617 1.00 8.36  ? 97  VAL E N   1 
ATOM   7137 C CA  . VAL E 5 97  ? 120.736 164.490 109.977 1.00 14.06 ? 97  VAL E CA  1 
ATOM   7138 C C   . VAL E 5 97  ? 121.023 163.278 110.847 1.00 16.06 ? 97  VAL E C   1 
ATOM   7139 O O   . VAL E 5 97  ? 120.960 163.348 112.077 1.00 32.59 ? 97  VAL E O   1 
ATOM   7140 C CB  . VAL E 5 97  ? 122.023 165.318 109.745 1.00 4.44  ? 97  VAL E CB  1 
ATOM   7141 C CG1 . VAL E 5 97  ? 123.068 164.506 108.994 1.00 4.50  ? 97  VAL E CG1 1 
ATOM   7142 C CG2 . VAL E 5 97  ? 121.695 166.610 109.004 1.00 4.52  ? 97  VAL E CG2 1 
ATOM   7143 N N   . ARG E 5 98  ? 121.334 162.161 110.195 1.00 17.12 ? 98  ARG E N   1 
ATOM   7144 C CA  . ARG E 5 98  ? 121.669 160.905 110.854 1.00 14.73 ? 98  ARG E CA  1 
ATOM   7145 C C   . ARG E 5 98  ? 123.165 160.674 110.715 1.00 11.24 ? 98  ARG E C   1 
ATOM   7146 O O   . ARG E 5 98  ? 123.752 161.008 109.682 1.00 24.19 ? 98  ARG E O   1 
ATOM   7147 C CB  . ARG E 5 98  ? 120.863 159.741 110.257 1.00 14.11 ? 98  ARG E CB  1 
ATOM   7148 C CG  . ARG E 5 98  ? 121.431 159.071 108.999 1.00 15.13 ? 98  ARG E CG  1 
ATOM   7149 C CD  . ARG E 5 98  ? 120.537 157.949 108.519 1.00 19.10 ? 98  ARG E CD  1 
ATOM   7150 N NE  . ARG E 5 98  ? 121.247 157.068 107.599 1.00 15.72 ? 98  ARG E NE  1 
ATOM   7151 C CZ  . ARG E 5 98  ? 120.770 155.935 107.099 1.00 22.16 ? 98  ARG E CZ  1 
ATOM   7152 N NH1 . ARG E 5 98  ? 119.561 155.489 107.407 1.00 34.62 ? 98  ARG E NH1 1 
ATOM   7153 N NH2 . ARG E 5 98  ? 121.529 155.224 106.272 1.00 26.05 ? 98  ARG E NH2 1 
ATOM   7154 N N   . SER E 5 99  ? 123.777 160.120 111.756 1.00 6.98  ? 99  SER E N   1 
ATOM   7155 C CA  . SER E 5 99  ? 125.200 159.817 111.758 1.00 1.58  ? 99  SER E CA  1 
ATOM   7156 C C   . SER E 5 99  ? 125.455 158.576 112.596 1.00 11.63 ? 99  SER E C   1 
ATOM   7157 O O   . SER E 5 99  ? 124.961 158.477 113.723 1.00 27.50 ? 99  SER E O   1 
ATOM   7158 C CB  . SER E 5 99  ? 125.996 160.991 112.309 1.00 7.80  ? 99  SER E CB  1 
ATOM   7159 O OG  . SER E 5 99  ? 125.925 161.000 113.719 1.00 29.64 ? 99  SER E OG  1 
ATOM   7160 N N   . ILE E 5 100 ? 126.230 157.641 112.050 1.00 2.66  ? 100 ILE E N   1 
ATOM   7161 C CA  . ILE E 5 100 ? 126.635 156.423 112.742 1.00 6.37  ? 100 ILE E CA  1 
ATOM   7162 C C   . ILE E 5 100 ? 128.155 156.354 112.725 1.00 12.50 ? 100 ILE E C   1 
ATOM   7163 O O   . ILE E 5 100 ? 128.779 156.556 111.677 1.00 15.82 ? 100 ILE E O   1 
ATOM   7164 C CB  . ILE E 5 100 ? 125.992 155.171 112.108 1.00 19.36 ? 100 ILE E CB  1 
ATOM   7165 C CG1 . ILE E 5 100 ? 126.089 153.962 113.045 1.00 21.24 ? 100 ILE E CG1 1 
ATOM   7166 C CG2 . ILE E 5 100 ? 126.579 154.861 110.733 1.00 23.24 ? 100 ILE E CG2 1 
ATOM   7167 C CD1 . ILE E 5 100 ? 125.113 152.866 112.703 1.00 22.76 ? 100 ILE E CD1 1 
ATOM   7168 N N   . TYR E 5 101 ? 128.746 156.106 113.893 1.00 16.45 ? 101 TYR E N   1 
ATOM   7169 C CA  . TYR E 5 101 ? 130.192 156.133 114.086 1.00 19.00 ? 101 TYR E CA  1 
ATOM   7170 C C   . TYR E 5 101 ? 130.694 154.752 114.477 1.00 13.43 ? 101 TYR E C   1 
ATOM   7171 O O   . TYR E 5 101 ? 130.400 154.260 115.570 1.00 15.01 ? 101 TYR E O   1 
ATOM   7172 C CB  . TYR E 5 101 ? 130.584 157.159 115.146 1.00 20.37 ? 101 TYR E CB  1 
ATOM   7173 C CG  . TYR E 5 101 ? 130.069 158.545 114.860 1.00 8.25  ? 101 TYR E CG  1 
ATOM   7174 C CD1 . TYR E 5 101 ? 130.708 159.366 113.949 1.00 11.02 ? 101 TYR E CD1 1 
ATOM   7175 C CD2 . TYR E 5 101 ? 128.943 159.030 115.494 1.00 17.42 ? 101 TYR E CD2 1 
ATOM   7176 C CE1 . TYR E 5 101 ? 130.241 160.629 113.683 1.00 13.68 ? 101 TYR E CE1 1 
ATOM   7177 C CE2 . TYR E 5 101 ? 128.475 160.288 115.240 1.00 12.27 ? 101 TYR E CE2 1 
ATOM   7178 C CZ  . TYR E 5 101 ? 129.124 161.084 114.332 1.00 7.21  ? 101 TYR E CZ  1 
ATOM   7179 O OH  . TYR E 5 101 ? 128.647 162.343 114.073 1.00 19.98 ? 101 TYR E OH  1 
ATOM   7180 N N   . TYR E 5 102 ? 131.445 154.140 113.572 1.00 15.39 ? 102 TYR E N   1 
ATOM   7181 C CA  . TYR E 5 102 ? 132.257 152.965 113.844 1.00 9.85  ? 102 TYR E CA  1 
ATOM   7182 C C   . TYR E 5 102 ? 133.346 152.965 112.783 1.00 18.89 ? 102 TYR E C   1 
ATOM   7183 O O   . TYR E 5 102 ? 133.426 153.882 111.963 1.00 24.16 ? 102 TYR E O   1 
ATOM   7184 C CB  . TYR E 5 102 ? 131.419 151.681 113.848 1.00 11.75 ? 102 TYR E CB  1 
ATOM   7185 C CG  . TYR E 5 102 ? 130.588 151.448 112.605 1.00 11.60 ? 102 TYR E CG  1 
ATOM   7186 C CD1 . TYR E 5 102 ? 131.128 150.840 111.484 1.00 12.12 ? 102 TYR E CD1 1 
ATOM   7187 C CD2 . TYR E 5 102 ? 129.257 151.829 112.561 1.00 13.50 ? 102 TYR E CD2 1 
ATOM   7188 C CE1 . TYR E 5 102 ? 130.371 150.628 110.356 1.00 19.77 ? 102 TYR E CE1 1 
ATOM   7189 C CE2 . TYR E 5 102 ? 128.494 151.621 111.438 1.00 13.20 ? 102 TYR E CE2 1 
ATOM   7190 C CZ  . TYR E 5 102 ? 129.055 151.021 110.338 1.00 17.65 ? 102 TYR E CZ  1 
ATOM   7191 O OH  . TYR E 5 102 ? 128.298 150.808 109.212 1.00 19.40 ? 102 TYR E OH  1 
ATOM   7192 N N   . TYR E 5 103 ? 134.203 151.950 112.811 1.00 17.24 ? 103 TYR E N   1 
ATOM   7193 C CA  . TYR E 5 103 ? 135.292 151.914 111.844 1.00 10.76 ? 103 TYR E CA  1 
ATOM   7194 C C   . TYR E 5 103 ? 134.745 151.726 110.435 1.00 19.97 ? 103 TYR E C   1 
ATOM   7195 O O   . TYR E 5 103 ? 134.088 150.724 110.136 1.00 26.92 ? 103 TYR E O   1 
ATOM   7196 C CB  . TYR E 5 103 ? 136.284 150.802 112.176 1.00 8.02  ? 103 TYR E CB  1 
ATOM   7197 C CG  . TYR E 5 103 ? 137.507 150.870 111.299 1.00 17.35 ? 103 TYR E CG  1 
ATOM   7198 C CD1 . TYR E 5 103 ? 138.498 151.808 111.538 1.00 17.49 ? 103 TYR E CD1 1 
ATOM   7199 C CD2 . TYR E 5 103 ? 137.659 150.021 110.215 1.00 27.68 ? 103 TYR E CD2 1 
ATOM   7200 C CE1 . TYR E 5 103 ? 139.610 151.890 110.732 1.00 12.50 ? 103 TYR E CE1 1 
ATOM   7201 C CE2 . TYR E 5 103 ? 138.771 150.095 109.402 1.00 27.85 ? 103 TYR E CE2 1 
ATOM   7202 C CZ  . TYR E 5 103 ? 139.740 151.034 109.664 1.00 20.34 ? 103 TYR E CZ  1 
ATOM   7203 O OH  . TYR E 5 103 ? 140.853 151.115 108.862 1.00 25.60 ? 103 TYR E OH  1 
ATOM   7204 N N   . GLY E 5 104 ? 135.024 152.696 109.567 1.00 21.68 ? 104 GLY E N   1 
ATOM   7205 C CA  . GLY E 5 104 ? 134.567 152.666 108.195 1.00 19.37 ? 104 GLY E CA  1 
ATOM   7206 C C   . GLY E 5 104 ? 133.177 153.215 107.955 1.00 17.87 ? 104 GLY E C   1 
ATOM   7207 O O   . GLY E 5 104 ? 132.685 153.124 106.825 1.00 18.66 ? 104 GLY E O   1 
ATOM   7208 N N   . SER E 5 105 ? 132.528 153.780 108.968 1.00 10.58 ? 105 SER E N   1 
ATOM   7209 C CA  . SER E 5 105 ? 131.190 154.322 108.791 1.00 9.85  ? 105 SER E CA  1 
ATOM   7210 C C   . SER E 5 105 ? 131.236 155.635 108.019 1.00 12.71 ? 105 SER E C   1 
ATOM   7211 O O   . SER E 5 105 ? 132.286 156.269 107.895 1.00 31.04 ? 105 SER E O   1 
ATOM   7212 C CB  . SER E 5 105 ? 130.525 154.545 110.144 1.00 13.81 ? 105 SER E CB  1 
ATOM   7213 O OG  . SER E 5 105 ? 131.138 155.615 110.836 1.00 23.05 ? 105 SER E OG  1 
ATOM   7214 N N   . SER E 5 106 ? 130.072 156.036 107.497 1.00 6.40  ? 106 SER E N   1 
ATOM   7215 C CA  . SER E 5 106 ? 129.917 157.279 106.756 1.00 9.42  ? 106 SER E CA  1 
ATOM   7216 C C   . SER E 5 106 ? 128.961 158.193 107.506 1.00 11.34 ? 106 SER E C   1 
ATOM   7217 O O   . SER E 5 106 ? 127.744 158.105 107.287 1.00 23.48 ? 106 SER E O   1 
ATOM   7218 C CB  . SER E 5 106 ? 129.387 156.999 105.354 1.00 16.77 ? 106 SER E CB  1 
ATOM   7219 O OG  . SER E 5 106 ? 128.429 155.960 105.374 1.00 17.11 ? 106 SER E OG  1 
ATOM   7220 N N   . PRO E 5 107 ? 129.437 159.078 108.381 1.00 16.34 ? 107 PRO E N   1 
ATOM   7221 C CA  . PRO E 5 107 ? 128.525 160.019 109.036 1.00 11.64 ? 107 PRO E CA  1 
ATOM   7222 C C   . PRO E 5 107 ? 127.941 161.029 108.062 1.00 16.78 ? 107 PRO E C   1 
ATOM   7223 O O   . PRO E 5 107 ? 128.480 161.270 106.980 1.00 31.09 ? 107 PRO E O   1 
ATOM   7224 C CB  . PRO E 5 107 ? 129.428 160.702 110.067 1.00 10.15 ? 107 PRO E CB  1 
ATOM   7225 C CG  . PRO E 5 107 ? 130.405 159.643 110.392 1.00 17.79 ? 107 PRO E CG  1 
ATOM   7226 C CD  . PRO E 5 107 ? 130.755 159.126 109.035 1.00 22.91 ? 107 PRO E CD  1 
ATOM   7227 N N   . PHE E 5 108 ? 126.813 161.617 108.463 1.00 19.13 ? 108 PHE E N   1 
ATOM   7228 C CA  . PHE E 5 108 ? 126.110 162.704 107.773 1.00 10.99 ? 108 PHE E CA  1 
ATOM   7229 C C   . PHE E 5 108 ? 125.549 162.235 106.434 1.00 14.44 ? 108 PHE E C   1 
ATOM   7230 O O   . PHE E 5 108 ? 125.284 163.062 105.549 1.00 16.87 ? 108 PHE E O   1 
ATOM   7231 C CB  . PHE E 5 108 ? 127.015 163.933 107.587 1.00 14.89 ? 108 PHE E CB  1 
ATOM   7232 C CG  . PHE E 5 108 ? 127.166 164.762 108.828 1.00 18.54 ? 108 PHE E CG  1 
ATOM   7233 C CD1 . PHE E 5 108 ? 127.956 164.328 109.874 1.00 12.30 ? 108 PHE E CD1 1 
ATOM   7234 C CD2 . PHE E 5 108 ? 126.525 165.981 108.944 1.00 19.73 ? 108 PHE E CD2 1 
ATOM   7235 C CE1 . PHE E 5 108 ? 128.094 165.087 111.008 1.00 18.85 ? 108 PHE E CE1 1 
ATOM   7236 C CE2 . PHE E 5 108 ? 126.661 166.743 110.078 1.00 6.83  ? 108 PHE E CE2 1 
ATOM   7237 C CZ  . PHE E 5 108 ? 127.447 166.297 111.110 1.00 19.02 ? 108 PHE E CZ  1 
ATOM   7238 N N   . ASP E 5 109 ? 125.326 160.929 106.265 1.00 19.24 ? 109 ASP E N   1 
ATOM   7239 C CA  . ASP E 5 109 ? 124.959 160.395 104.954 1.00 25.83 ? 109 ASP E CA  1 
ATOM   7240 C C   . ASP E 5 109 ? 123.577 160.860 104.497 1.00 25.52 ? 109 ASP E C   1 
ATOM   7241 O O   . ASP E 5 109 ? 123.397 161.204 103.322 1.00 27.57 ? 109 ASP E O   1 
ATOM   7242 C CB  . ASP E 5 109 ? 125.059 158.864 104.965 1.00 25.36 ? 109 ASP E CB  1 
ATOM   7243 C CG  . ASP E 5 109 ? 124.173 158.200 106.018 1.00 23.85 ? 109 ASP E CG  1 
ATOM   7244 O OD1 . ASP E 5 109 ? 123.213 158.817 106.518 1.00 27.57 ? 109 ASP E OD1 1 
ATOM   7245 O OD2 . ASP E 5 109 ? 124.469 157.041 106.371 1.00 29.43 ? 109 ASP E OD2 1 
ATOM   7246 N N   . PHE E 5 110 ? 122.593 160.874 105.400 1.00 3.45  ? 110 PHE E N   1 
ATOM   7247 C CA  . PHE E 5 110 ? 121.202 161.169 105.063 1.00 10.37 ? 110 PHE E CA  1 
ATOM   7248 C C   . PHE E 5 110 ? 120.722 162.406 105.807 1.00 8.16  ? 110 PHE E C   1 
ATOM   7249 O O   . PHE E 5 110 ? 120.956 162.542 107.011 1.00 16.75 ? 110 PHE E O   1 
ATOM   7250 C CB  . PHE E 5 110 ? 120.292 159.980 105.383 1.00 31.11 ? 110 PHE E CB  1 
ATOM   7251 C CG  . PHE E 5 110 ? 118.967 160.030 104.674 1.00 26.55 ? 110 PHE E CG  1 
ATOM   7252 C CD1 . PHE E 5 110 ? 118.880 159.800 103.313 1.00 22.21 ? 110 PHE E CD1 1 
ATOM   7253 C CD2 . PHE E 5 110 ? 117.812 160.323 105.368 1.00 25.56 ? 110 PHE E CD2 1 
ATOM   7254 C CE1 . PHE E 5 110 ? 117.671 159.860 102.665 1.00 21.52 ? 110 PHE E CE1 1 
ATOM   7255 C CE2 . PHE E 5 110 ? 116.600 160.384 104.723 1.00 22.81 ? 110 PHE E CE2 1 
ATOM   7256 C CZ  . PHE E 5 110 ? 116.529 160.151 103.371 1.00 22.12 ? 110 PHE E CZ  1 
ATOM   7257 N N   . TRP E 5 111 ? 120.041 163.293 105.081 1.00 11.73 ? 111 TRP E N   1 
ATOM   7258 C CA  . TRP E 5 111 ? 119.543 164.567 105.586 1.00 6.21  ? 111 TRP E CA  1 
ATOM   7259 C C   . TRP E 5 111 ? 118.049 164.649 105.313 1.00 12.21 ? 111 TRP E C   1 
ATOM   7260 O O   . TRP E 5 111 ? 117.594 164.254 104.235 1.00 36.88 ? 111 TRP E O   1 
ATOM   7261 C CB  . TRP E 5 111 ? 120.241 165.754 104.906 1.00 22.80 ? 111 TRP E CB  1 
ATOM   7262 C CG  . TRP E 5 111 ? 121.721 165.918 105.178 1.00 23.46 ? 111 TRP E CG  1 
ATOM   7263 C CD1 . TRP E 5 111 ? 122.704 164.988 105.003 1.00 17.45 ? 111 TRP E CD1 1 
ATOM   7264 C CD2 . TRP E 5 111 ? 122.376 167.103 105.642 1.00 12.85 ? 111 TRP E CD2 1 
ATOM   7265 N NE1 . TRP E 5 111 ? 123.923 165.514 105.343 1.00 9.96  ? 111 TRP E NE1 1 
ATOM   7266 C CE2 . TRP E 5 111 ? 123.749 166.813 105.737 1.00 20.26 ? 111 TRP E CE2 1 
ATOM   7267 C CE3 . TRP E 5 111 ? 121.932 168.380 105.993 1.00 6.94  ? 111 TRP E CE3 1 
ATOM   7268 C CZ2 . TRP E 5 111 ? 124.681 167.751 106.171 1.00 21.64 ? 111 TRP E CZ2 1 
ATOM   7269 C CZ3 . TRP E 5 111 ? 122.857 169.308 106.421 1.00 19.94 ? 111 TRP E CZ3 1 
ATOM   7270 C CH2 . TRP E 5 111 ? 124.216 168.990 106.505 1.00 23.53 ? 111 TRP E CH2 1 
ATOM   7271 N N   . GLY E 5 112 ? 117.288 165.165 106.274 1.00 10.42 ? 112 GLY E N   1 
ATOM   7272 C CA  . GLY E 5 112 ? 115.876 165.391 106.047 1.00 12.80 ? 112 GLY E CA  1 
ATOM   7273 C C   . GLY E 5 112 ? 115.625 166.587 105.149 1.00 16.90 ? 112 GLY E C   1 
ATOM   7274 O O   . GLY E 5 112 ? 116.531 167.340 104.800 1.00 19.07 ? 112 GLY E O   1 
ATOM   7275 N N   . GLN E 5 113 ? 114.362 166.756 104.745 1.00 22.48 ? 113 GLN E N   1 
ATOM   7276 C CA  . GLN E 5 113 ? 114.021 167.872 103.864 1.00 29.88 ? 113 GLN E CA  1 
ATOM   7277 C C   . GLN E 5 113 ? 114.139 169.209 104.585 1.00 30.49 ? 113 GLN E C   1 
ATOM   7278 O O   . GLN E 5 113 ? 114.664 170.177 104.024 1.00 38.22 ? 113 GLN E O   1 
ATOM   7279 C CB  . GLN E 5 113 ? 112.613 167.706 103.289 1.00 33.54 ? 113 GLN E CB  1 
ATOM   7280 C CG  . GLN E 5 113 ? 112.313 166.344 102.682 1.00 34.22 ? 113 GLN E CG  1 
ATOM   7281 C CD  . GLN E 5 113 ? 111.379 165.521 103.540 1.00 40.41 ? 113 GLN E CD  1 
ATOM   7282 O OE1 . GLN E 5 113 ? 111.735 165.108 104.640 1.00 34.37 ? 113 GLN E OE1 1 
ATOM   7283 N NE2 . GLN E 5 113 ? 110.171 165.278 103.041 1.00 38.33 ? 113 GLN E NE2 1 
ATOM   7284 N N   . GLY E 5 114 ? 113.633 169.291 105.811 1.00 23.07 ? 114 GLY E N   1 
ATOM   7285 C CA  . GLY E 5 114 ? 113.820 170.442 106.667 1.00 26.20 ? 114 GLY E CA  1 
ATOM   7286 C C   . GLY E 5 114 ? 112.561 171.281 106.809 1.00 30.13 ? 114 GLY E C   1 
ATOM   7287 O O   . GLY E 5 114 ? 111.670 171.279 105.956 1.00 33.50 ? 114 GLY E O   1 
ATOM   7288 N N   . THR E 5 115 ? 112.503 172.016 107.922 1.00 39.19 ? 115 THR E N   1 
ATOM   7289 C CA  . THR E 5 115 ? 111.377 172.871 108.281 1.00 41.68 ? 115 THR E CA  1 
ATOM   7290 C C   . THR E 5 115 ? 111.819 174.323 108.340 1.00 39.63 ? 115 THR E C   1 
ATOM   7291 O O   . THR E 5 115 ? 112.809 174.650 109.000 1.00 42.36 ? 115 THR E O   1 
ATOM   7292 C CB  . THR E 5 115 ? 110.783 172.480 109.634 1.00 41.39 ? 115 THR E CB  1 
ATOM   7293 O OG1 . THR E 5 115 ? 111.830 172.340 110.603 1.00 41.05 ? 115 THR E OG1 1 
ATOM   7294 C CG2 . THR E 5 115 ? 109.976 171.207 109.532 1.00 39.62 ? 115 THR E CG2 1 
ATOM   7295 N N   . THR E 5 116 ? 111.073 175.188 107.662 1.00 43.82 ? 116 THR E N   1 
ATOM   7296 C CA  . THR E 5 116 ? 111.324 176.618 107.748 1.00 45.20 ? 116 THR E CA  1 
ATOM   7297 C C   . THR E 5 116 ? 110.987 177.135 109.140 1.00 46.28 ? 116 THR E C   1 
ATOM   7298 O O   . THR E 5 116 ? 109.979 176.748 109.738 1.00 52.37 ? 116 THR E O   1 
ATOM   7299 C CB  . THR E 5 116 ? 110.504 177.380 106.703 1.00 44.79 ? 116 THR E CB  1 
ATOM   7300 O OG1 . THR E 5 116 ? 110.836 178.772 106.765 1.00 47.53 ? 116 THR E OG1 1 
ATOM   7301 C CG2 . THR E 5 116 ? 108.992 177.235 106.947 1.00 42.62 ? 116 THR E CG2 1 
ATOM   7302 N N   . LEU E 5 117 ? 111.853 178.001 109.660 1.00 40.48 ? 117 LEU E N   1 
ATOM   7303 C CA  . LEU E 5 117 ? 111.583 178.797 110.849 1.00 40.09 ? 117 LEU E CA  1 
ATOM   7304 C C   . LEU E 5 117 ? 111.832 180.254 110.498 1.00 43.08 ? 117 LEU E C   1 
ATOM   7305 O O   . LEU E 5 117 ? 112.876 180.584 109.928 1.00 52.55 ? 117 LEU E O   1 
ATOM   7306 C CB  . LEU E 5 117 ? 112.469 178.382 112.026 1.00 38.45 ? 117 LEU E CB  1 
ATOM   7307 C CG  . LEU E 5 117 ? 111.953 178.757 113.419 1.00 44.27 ? 117 LEU E CG  1 
ATOM   7308 C CD1 . LEU E 5 117 ? 110.831 177.832 113.864 1.00 47.94 ? 117 LEU E CD1 1 
ATOM   7309 C CD2 . LEU E 5 117 ? 113.084 178.754 114.430 1.00 42.38 ? 117 LEU E CD2 1 
ATOM   7310 N N   . THR E 5 118 ? 110.863 181.110 110.808 1.00 43.96 ? 118 THR E N   1 
ATOM   7311 C CA  . THR E 5 118 ? 110.978 182.551 110.621 1.00 47.98 ? 118 THR E CA  1 
ATOM   7312 C C   . THR E 5 118 ? 110.656 183.233 111.943 1.00 51.90 ? 118 THR E C   1 
ATOM   7313 O O   . THR E 5 118 ? 109.674 182.879 112.603 1.00 54.74 ? 118 THR E O   1 
ATOM   7314 C CB  . THR E 5 118 ? 110.062 183.038 109.485 1.00 48.40 ? 118 THR E CB  1 
ATOM   7315 O OG1 . THR E 5 118 ? 110.367 184.400 109.167 1.00 52.72 ? 118 THR E OG1 1 
ATOM   7316 C CG2 . THR E 5 118 ? 108.591 182.914 109.841 1.00 50.71 ? 118 THR E CG2 1 
ATOM   7317 N N   . VAL E 5 119 ? 111.502 184.185 112.332 1.00 46.83 ? 119 VAL E N   1 
ATOM   7318 C CA  . VAL E 5 119 ? 111.430 184.824 113.643 1.00 40.22 ? 119 VAL E CA  1 
ATOM   7319 C C   . VAL E 5 119 ? 111.442 186.336 113.470 1.00 42.96 ? 119 VAL E C   1 
ATOM   7320 O O   . VAL E 5 119 ? 110.395 186.981 113.514 1.00 41.66 ? 119 VAL E O   1 
ATOM   7321 C CB  . VAL E 5 119 ? 112.591 184.357 114.551 1.00 39.75 ? 119 VAL E CB  1 
ATOM   7322 C CG1 . VAL E 5 119 ? 112.411 184.881 115.974 1.00 42.20 ? 119 VAL E CG1 1 
ATOM   7323 C CG2 . VAL E 5 119 ? 112.693 182.832 114.541 1.00 43.40 ? 119 VAL E CG2 1 
ATOM   7324 N N   . ASP E 5 137 ? 137.931 176.658 117.503 1.00 46.85 ? 125 ASP E N   1 
ATOM   7325 C CA  . ASP E 5 137 ? 137.042 176.663 116.348 1.00 51.34 ? 125 ASP E CA  1 
ATOM   7326 C C   . ASP E 5 137 ? 137.828 176.651 115.045 1.00 50.06 ? 125 ASP E C   1 
ATOM   7327 O O   . ASP E 5 137 ? 138.419 177.658 114.660 1.00 50.73 ? 125 ASP E O   1 
ATOM   7328 C CB  . ASP E 5 137 ? 136.125 177.887 116.380 1.00 47.28 ? 125 ASP E CB  1 
ATOM   7329 C CG  . ASP E 5 137 ? 134.838 177.632 117.134 1.00 53.00 ? 125 ASP E CG  1 
ATOM   7330 O OD1 . ASP E 5 137 ? 134.859 176.850 118.106 1.00 50.02 ? 125 ASP E OD1 1 
ATOM   7331 O OD2 . ASP E 5 137 ? 133.803 178.214 116.751 1.00 56.18 ? 125 ASP E OD2 1 
ATOM   7332 N N   . ILE E 5 138 ? 137.828 175.501 114.368 1.00 37.13 ? 126 ILE E N   1 
ATOM   7333 C CA  . ILE E 5 138 ? 138.449 175.421 113.054 1.00 34.36 ? 126 ILE E CA  1 
ATOM   7334 C C   . ILE E 5 138 ? 137.643 176.271 112.086 1.00 31.16 ? 126 ILE E C   1 
ATOM   7335 O O   . ILE E 5 138 ? 136.409 176.191 112.040 1.00 37.06 ? 126 ILE E O   1 
ATOM   7336 C CB  . ILE E 5 138 ? 138.536 173.954 112.598 1.00 29.80 ? 126 ILE E CB  1 
ATOM   7337 C CG1 . ILE E 5 138 ? 139.681 173.252 113.320 1.00 27.69 ? 126 ILE E CG1 1 
ATOM   7338 C CG2 . ILE E 5 138 ? 138.767 173.842 111.093 1.00 31.16 ? 126 ILE E CG2 1 
ATOM   7339 C CD1 . ILE E 5 138 ? 139.487 171.761 113.482 1.00 30.23 ? 126 ILE E CD1 1 
ATOM   7340 N N   . VAL E 5 139 ? 138.341 177.095 111.308 1.00 31.90 ? 127 VAL E N   1 
ATOM   7341 C CA  . VAL E 5 139 ? 137.724 178.027 110.371 1.00 37.07 ? 127 VAL E CA  1 
ATOM   7342 C C   . VAL E 5 139 ? 137.891 177.453 108.973 1.00 35.53 ? 127 VAL E C   1 
ATOM   7343 O O   . VAL E 5 139 ? 139.015 177.346 108.469 1.00 42.35 ? 127 VAL E O   1 
ATOM   7344 C CB  . VAL E 5 139 ? 138.346 179.432 110.495 1.00 41.37 ? 127 VAL E CB  1 
ATOM   7345 C CG1 . VAL E 5 139 ? 138.276 180.234 109.181 1.00 37.49 ? 127 VAL E CG1 1 
ATOM   7346 C CG2 . VAL E 5 139 ? 137.666 180.203 111.620 1.00 40.60 ? 127 VAL E CG2 1 
ATOM   7347 N N   . MET E 5 140 ? 136.771 177.115 108.341 1.00 36.93 ? 128 MET E N   1 
ATOM   7348 C CA  . MET E 5 140 ? 136.745 176.519 107.013 1.00 39.62 ? 128 MET E CA  1 
ATOM   7349 C C   . MET E 5 140 ? 136.390 177.594 106.001 1.00 37.60 ? 128 MET E C   1 
ATOM   7350 O O   . MET E 5 140 ? 135.359 178.260 106.139 1.00 41.73 ? 128 MET E O   1 
ATOM   7351 C CB  . MET E 5 140 ? 135.738 175.368 106.942 1.00 32.16 ? 128 MET E CB  1 
ATOM   7352 C CG  . MET E 5 140 ? 135.957 174.265 107.989 1.00 32.51 ? 128 MET E CG  1 
ATOM   7353 S SD  . MET E 5 140 ? 137.416 173.213 107.787 1.00 35.15 ? 128 MET E SD  1 
ATOM   7354 C CE  . MET E 5 140 ? 137.457 172.860 106.037 1.00 37.48 ? 128 MET E CE  1 
ATOM   7355 N N   . THR E 5 141 ? 137.249 177.764 104.999 1.00 35.23 ? 129 THR E N   1 
ATOM   7356 C CA  . THR E 5 141 ? 137.102 178.795 103.980 1.00 40.66 ? 129 THR E CA  1 
ATOM   7357 C C   . THR E 5 141 ? 137.025 178.146 102.605 1.00 44.56 ? 129 THR E C   1 
ATOM   7358 O O   . THR E 5 141 ? 137.853 177.293 102.266 1.00 47.90 ? 129 THR E O   1 
ATOM   7359 C CB  . THR E 5 141 ? 138.258 179.809 104.050 1.00 44.41 ? 129 THR E CB  1 
ATOM   7360 O OG1 . THR E 5 141 ? 137.981 180.916 103.183 1.00 48.18 ? 129 THR E OG1 1 
ATOM   7361 C CG2 . THR E 5 141 ? 139.603 179.188 103.671 1.00 42.52 ? 129 THR E CG2 1 
ATOM   7362 N N   . GLN E 5 142 ? 136.008 178.529 101.838 1.00 53.19 ? 130 GLN E N   1 
ATOM   7363 C CA  . GLN E 5 142 ? 135.890 178.194 100.425 1.00 52.76 ? 130 GLN E CA  1 
ATOM   7364 C C   . GLN E 5 142 ? 136.174 179.464 99.637  1.00 55.84 ? 130 GLN E C   1 
ATOM   7365 O O   . GLN E 5 142 ? 135.435 180.448 99.756  1.00 51.14 ? 130 GLN E O   1 
ATOM   7366 C CB  . GLN E 5 142 ? 134.503 177.643 100.101 1.00 50.32 ? 130 GLN E CB  1 
ATOM   7367 N N   . ALA E 5 143 ? 137.246 179.440 98.842  1.00 67.09 ? 131 ALA E N   1 
ATOM   7368 C CA  . ALA E 5 143 ? 137.756 180.671 98.243  1.00 66.93 ? 131 ALA E CA  1 
ATOM   7369 C C   . ALA E 5 143 ? 136.781 181.251 97.227  1.00 66.13 ? 131 ALA E C   1 
ATOM   7370 O O   . ALA E 5 143 ? 136.570 182.469 97.188  1.00 64.38 ? 131 ALA E O   1 
ATOM   7371 C CB  . ALA E 5 143 ? 139.110 180.407 97.588  1.00 63.00 ? 131 ALA E CB  1 
ATOM   7372 N N   . THR E 5 144 ? 136.173 180.399 96.408  1.00 63.75 ? 132 THR E N   1 
ATOM   7373 C CA  . THR E 5 144 ? 135.342 180.825 95.288  1.00 62.99 ? 132 THR E CA  1 
ATOM   7374 C C   . THR E 5 144 ? 133.880 180.806 95.710  1.00 65.06 ? 132 THR E C   1 
ATOM   7375 O O   . THR E 5 144 ? 133.407 179.818 96.279  1.00 62.99 ? 132 THR E O   1 
ATOM   7376 C CB  . THR E 5 144 ? 135.560 179.920 94.076  1.00 58.23 ? 132 THR E CB  1 
ATOM   7377 N N   . SER E 5 145 ? 133.182 181.918 95.464  1.00 69.89 ? 133 SER E N   1 
ATOM   7378 C CA  . SER E 5 145 ? 131.735 181.946 95.652  1.00 66.86 ? 133 SER E CA  1 
ATOM   7379 C C   . SER E 5 145 ? 131.019 181.228 94.515  1.00 64.89 ? 133 SER E C   1 
ATOM   7380 O O   . SER E 5 145 ? 130.034 180.517 94.744  1.00 63.28 ? 133 SER E O   1 
ATOM   7381 C CB  . SER E 5 145 ? 131.251 183.392 95.764  1.00 68.19 ? 133 SER E CB  1 
ATOM   7382 O OG  . SER E 5 145 ? 131.709 184.176 94.677  1.00 66.50 ? 133 SER E OG  1 
ATOM   7383 N N   . SER E 5 146 ? 131.498 181.406 93.283  1.00 64.67 ? 134 SER E N   1 
ATOM   7384 C CA  . SER E 5 146 ? 130.897 180.802 92.102  1.00 65.08 ? 134 SER E CA  1 
ATOM   7385 C C   . SER E 5 146 ? 131.999 180.427 91.125  1.00 65.78 ? 134 SER E C   1 
ATOM   7386 O O   . SER E 5 146 ? 133.109 180.963 91.194  1.00 68.11 ? 134 SER E O   1 
ATOM   7387 C CB  . SER E 5 146 ? 129.905 181.750 91.424  1.00 64.16 ? 134 SER E CB  1 
ATOM   7388 O OG  . SER E 5 146 ? 130.559 182.924 90.972  1.00 65.49 ? 134 SER E OG  1 
ATOM   7389 N N   . VAL E 5 147 ? 131.693 179.491 90.236  1.00 62.62 ? 135 VAL E N   1 
ATOM   7390 C CA  . VAL E 5 147 ? 132.614 179.020 89.208  1.00 66.11 ? 135 VAL E CA  1 
ATOM   7391 C C   . VAL E 5 147 ? 131.812 178.811 87.933  1.00 66.54 ? 135 VAL E C   1 
ATOM   7392 O O   . VAL E 5 147 ? 130.766 178.155 87.981  1.00 63.47 ? 135 VAL E O   1 
ATOM   7393 C CB  . VAL E 5 147 ? 133.332 177.722 89.626  1.00 65.14 ? 135 VAL E CB  1 
ATOM   7394 C CG1 . VAL E 5 147 ? 133.750 176.850 88.421  1.00 65.88 ? 135 VAL E CG1 1 
ATOM   7395 C CG2 . VAL E 5 147 ? 134.538 178.056 90.490  1.00 67.03 ? 135 VAL E CG2 1 
ATOM   7396 N N   . PRO E 5 148 ? 132.244 179.310 86.765  1.00 74.35 ? 136 PRO E N   1 
ATOM   7397 C CA  . PRO E 5 148 ? 131.568 178.913 85.523  1.00 74.09 ? 136 PRO E CA  1 
ATOM   7398 C C   . PRO E 5 148 ? 131.992 177.516 85.097  1.00 73.88 ? 136 PRO E C   1 
ATOM   7399 O O   . PRO E 5 148 ? 133.159 177.140 85.227  1.00 72.52 ? 136 PRO E O   1 
ATOM   7400 C CB  . PRO E 5 148 ? 132.023 179.966 84.509  1.00 73.28 ? 136 PRO E CB  1 
ATOM   7401 C CG  . PRO E 5 148 ? 133.328 180.420 85.000  1.00 73.90 ? 136 PRO E CG  1 
ATOM   7402 C CD  . PRO E 5 148 ? 133.290 180.320 86.495  1.00 71.20 ? 136 PRO E CD  1 
ATOM   7403 N N   . VAL E 5 149 ? 131.029 176.749 84.582  1.00 74.64 ? 137 VAL E N   1 
ATOM   7404 C CA  . VAL E 5 149 ? 131.257 175.378 84.145  1.00 73.63 ? 137 VAL E CA  1 
ATOM   7405 C C   . VAL E 5 149 ? 130.673 175.204 82.752  1.00 74.40 ? 137 VAL E C   1 
ATOM   7406 O O   . VAL E 5 149 ? 129.689 175.854 82.383  1.00 71.93 ? 137 VAL E O   1 
ATOM   7407 C CB  . VAL E 5 149 ? 130.645 174.339 85.121  1.00 73.83 ? 137 VAL E CB  1 
ATOM   7408 C CG1 . VAL E 5 149 ? 131.001 174.670 86.566  1.00 71.45 ? 137 VAL E CG1 1 
ATOM   7409 C CG2 . VAL E 5 149 ? 129.132 174.208 84.943  1.00 73.01 ? 137 VAL E CG2 1 
ATOM   7410 N N   . THR E 5 150 ? 131.296 174.317 81.980  1.00 78.35 ? 138 THR E N   1 
ATOM   7411 C CA  . THR E 5 150 ? 130.764 173.794 80.737  1.00 77.98 ? 138 THR E CA  1 
ATOM   7412 C C   . THR E 5 150 ? 130.368 172.340 80.976  1.00 77.76 ? 138 THR E C   1 
ATOM   7413 O O   . THR E 5 150 ? 131.106 171.631 81.676  1.00 75.33 ? 138 THR E O   1 
ATOM   7414 C CB  . THR E 5 150 ? 131.805 173.873 79.610  1.00 71.96 ? 138 THR E CB  1 
ATOM   7415 N N   . PRO E 5 151 ? 129.220 171.859 80.477  1.00 79.46 ? 139 PRO E N   1 
ATOM   7416 C CA  . PRO E 5 151 ? 128.955 170.416 80.563  1.00 76.42 ? 139 PRO E CA  1 
ATOM   7417 C C   . PRO E 5 151 ? 130.040 169.609 79.865  1.00 74.87 ? 139 PRO E C   1 
ATOM   7418 O O   . PRO E 5 151 ? 130.526 169.978 78.795  1.00 74.34 ? 139 PRO E O   1 
ATOM   7419 C CB  . PRO E 5 151 ? 127.599 170.251 79.869  1.00 75.84 ? 139 PRO E CB  1 
ATOM   7420 C CG  . PRO E 5 151 ? 126.963 171.572 79.889  1.00 76.35 ? 139 PRO E CG  1 
ATOM   7421 C CD  . PRO E 5 151 ? 127.994 172.617 80.159  1.00 77.49 ? 139 PRO E CD  1 
ATOM   7422 N N   . GLY E 5 152 ? 130.418 168.498 80.490  1.00 70.78 ? 140 GLY E N   1 
ATOM   7423 C CA  . GLY E 5 152 ? 131.521 167.693 80.012  1.00 70.25 ? 140 GLY E CA  1 
ATOM   7424 C C   . GLY E 5 152 ? 132.897 168.237 80.329  1.00 70.00 ? 140 GLY E C   1 
ATOM   7425 O O   . GLY E 5 152 ? 133.884 167.704 79.807  1.00 67.37 ? 140 GLY E O   1 
ATOM   7426 N N   . GLU E 5 153 ? 132.996 169.266 81.171  1.00 71.94 ? 141 GLU E N   1 
ATOM   7427 C CA  . GLU E 5 153 ? 134.252 169.929 81.500  1.00 71.99 ? 141 GLU E CA  1 
ATOM   7428 C C   . GLU E 5 153 ? 134.590 169.683 82.963  1.00 72.76 ? 141 GLU E C   1 
ATOM   7429 O O   . GLU E 5 153 ? 133.726 169.820 83.836  1.00 73.14 ? 141 GLU E O   1 
ATOM   7430 C CB  . GLU E 5 153 ? 134.161 171.431 81.227  1.00 69.03 ? 141 GLU E CB  1 
ATOM   7431 N N   . SER E 5 154 ? 135.842 169.318 83.225  1.00 69.80 ? 142 SER E N   1 
ATOM   7432 C CA  . SER E 5 154 ? 136.273 169.060 84.591  1.00 71.32 ? 142 SER E CA  1 
ATOM   7433 C C   . SER E 5 154 ? 136.311 170.353 85.398  1.00 69.94 ? 142 SER E C   1 
ATOM   7434 O O   . SER E 5 154 ? 136.639 171.421 84.875  1.00 65.53 ? 142 SER E O   1 
ATOM   7435 C CB  . SER E 5 154 ? 137.650 168.395 84.593  1.00 66.74 ? 142 SER E CB  1 
ATOM   7436 O OG  . SER E 5 154 ? 138.256 168.479 85.870  1.00 66.50 ? 142 SER E OG  1 
ATOM   7437 N N   . VAL E 5 155 ? 135.963 170.245 86.681  1.00 63.54 ? 143 VAL E N   1 
ATOM   7438 C CA  . VAL E 5 155 ? 135.939 171.369 87.612  1.00 62.07 ? 143 VAL E CA  1 
ATOM   7439 C C   . VAL E 5 155 ? 136.576 170.918 88.918  1.00 60.19 ? 143 VAL E C   1 
ATOM   7440 O O   . VAL E 5 155 ? 136.408 169.765 89.331  1.00 57.97 ? 143 VAL E O   1 
ATOM   7441 C CB  . VAL E 5 155 ? 134.503 171.880 87.860  1.00 63.36 ? 143 VAL E CB  1 
ATOM   7442 C CG1 . VAL E 5 155 ? 134.515 173.051 88.842  1.00 62.15 ? 143 VAL E CG1 1 
ATOM   7443 C CG2 . VAL E 5 155 ? 133.829 172.276 86.545  1.00 62.48 ? 143 VAL E CG2 1 
ATOM   7444 N N   . SER E 5 156 ? 137.312 171.826 89.561  1.00 56.36 ? 144 SER E N   1 
ATOM   7445 C CA  . SER E 5 156 ? 137.955 171.578 90.846  1.00 57.82 ? 144 SER E CA  1 
ATOM   7446 C C   . SER E 5 156 ? 137.499 172.629 91.848  1.00 59.16 ? 144 SER E C   1 
ATOM   7447 O O   . SER E 5 156 ? 137.502 173.826 91.541  1.00 59.29 ? 144 SER E O   1 
ATOM   7448 C CB  . SER E 5 156 ? 139.478 171.599 90.716  1.00 58.23 ? 144 SER E CB  1 
ATOM   7449 O OG  . SER E 5 156 ? 140.086 170.918 91.799  1.00 58.96 ? 144 SER E OG  1 
ATOM   7450 N N   . ILE E 5 157 ? 137.113 172.172 93.038  1.00 52.85 ? 145 ILE E N   1 
ATOM   7451 C CA  . ILE E 5 157 ? 136.652 173.021 94.132  1.00 52.81 ? 145 ILE E CA  1 
ATOM   7452 C C   . ILE E 5 157 ? 137.628 172.802 95.278  1.00 50.99 ? 145 ILE E C   1 
ATOM   7453 O O   . ILE E 5 157 ? 138.066 171.670 95.509  1.00 54.18 ? 145 ILE E O   1 
ATOM   7454 C CB  . ILE E 5 157 ? 135.199 172.677 94.523  1.00 53.07 ? 145 ILE E CB  1 
ATOM   7455 C CG1 . ILE E 5 157 ? 134.286 173.013 93.338  1.00 51.74 ? 145 ILE E CG1 1 
ATOM   7456 C CG2 . ILE E 5 157 ? 134.695 173.469 95.779  1.00 54.61 ? 145 ILE E CG2 1 
ATOM   7457 C CD1 . ILE E 5 157 ? 132.812 172.964 93.622  1.00 50.75 ? 145 ILE E CD1 1 
ATOM   7458 N N   . SER E 5 158 ? 137.967 173.881 95.988  1.00 44.90 ? 146 SER E N   1 
ATOM   7459 C CA  . SER E 5 158 ? 139.019 173.877 96.998  1.00 50.53 ? 146 SER E CA  1 
ATOM   7460 C C   . SER E 5 158 ? 138.489 174.403 98.323  1.00 49.45 ? 146 SER E C   1 
ATOM   7461 O O   . SER E 5 158 ? 137.608 175.265 98.353  1.00 57.91 ? 146 SER E O   1 
ATOM   7462 C CB  . SER E 5 158 ? 140.208 174.726 96.544  1.00 57.59 ? 146 SER E CB  1 
ATOM   7463 O OG  . SER E 5 158 ? 139.768 175.853 95.807  1.00 58.41 ? 146 SER E OG  1 
ATOM   7464 N N   . CYS E 5 159 ? 139.040 173.874 99.415  1.00 39.25 ? 147 CYS E N   1 
ATOM   7465 C CA  . CYS E 5 159 ? 138.710 174.288 100.770 1.00 43.42 ? 147 CYS E CA  1 
ATOM   7466 C C   . CYS E 5 159 ? 139.980 174.265 101.609 1.00 46.21 ? 147 CYS E C   1 
ATOM   7467 O O   . CYS E 5 159 ? 140.925 173.536 101.299 1.00 56.25 ? 147 CYS E O   1 
ATOM   7468 C CB  . CYS E 5 159 ? 137.643 173.369 101.392 1.00 44.65 ? 147 CYS E CB  1 
ATOM   7469 S SG  . CYS E 5 159 ? 136.842 174.024 102.878 1.00 64.06 ? 147 CYS E SG  1 
ATOM   7470 N N   . ARG E 5 160 ? 140.001 175.076 102.667 1.00 40.01 ? 148 ARG E N   1 
ATOM   7471 C CA  . ARG E 5 160 ? 141.152 175.174 103.556 1.00 37.59 ? 148 ARG E CA  1 
ATOM   7472 C C   . ARG E 5 160 ? 140.655 175.275 104.992 1.00 40.20 ? 148 ARG E C   1 
ATOM   7473 O O   . ARG E 5 160 ? 139.583 175.822 105.259 1.00 44.36 ? 148 ARG E O   1 
ATOM   7474 C CB  . ARG E 5 160 ? 142.041 176.379 103.182 1.00 42.86 ? 148 ARG E CB  1 
ATOM   7475 C CG  . ARG E 5 160 ? 142.987 176.885 104.283 1.00 45.96 ? 148 ARG E CG  1 
ATOM   7476 C CD  . ARG E 5 160 ? 143.994 177.901 103.770 1.00 45.21 ? 148 ARG E CD  1 
ATOM   7477 N NE  . ARG E 5 160 ? 143.382 179.209 103.551 1.00 46.69 ? 148 ARG E NE  1 
ATOM   7478 C CZ  . ARG E 5 160 ? 143.355 180.211 104.425 1.00 46.21 ? 148 ARG E CZ  1 
ATOM   7479 N NH1 . ARG E 5 160 ? 143.850 180.093 105.650 1.00 46.40 ? 148 ARG E NH1 1 
ATOM   7480 N NH2 . ARG E 5 160 ? 142.801 181.365 104.066 1.00 42.18 ? 148 ARG E NH2 1 
ATOM   7481 N N   . SER E 5 161 ? 141.461 174.749 105.915 1.00 37.24 ? 149 SER E N   1 
ATOM   7482 C CA  . SER E 5 161 ? 141.177 174.754 107.344 1.00 39.89 ? 149 SER E CA  1 
ATOM   7483 C C   . SER E 5 161 ? 142.209 175.603 108.071 1.00 43.46 ? 149 SER E C   1 
ATOM   7484 O O   . SER E 5 161 ? 143.334 175.769 107.596 1.00 47.11 ? 149 SER E O   1 
ATOM   7485 C CB  . SER E 5 161 ? 141.192 173.335 107.911 1.00 39.70 ? 149 SER E CB  1 
ATOM   7486 O OG  . SER E 5 161 ? 141.157 173.359 109.325 1.00 43.42 ? 149 SER E OG  1 
ATOM   7487 N N   . SER E 5 162 ? 141.816 176.163 109.216 1.00 40.45 ? 150 SER E N   1 
ATOM   7488 C CA  . SER E 5 162 ? 142.774 176.895 110.038 1.00 39.93 ? 150 SER E CA  1 
ATOM   7489 C C   . SER E 5 162 ? 143.792 175.951 110.661 1.00 42.73 ? 150 SER E C   1 
ATOM   7490 O O   . SER E 5 162 ? 144.985 176.268 110.726 1.00 51.23 ? 150 SER E O   1 
ATOM   7491 C CB  . SER E 5 162 ? 142.044 177.680 111.123 1.00 41.94 ? 150 SER E CB  1 
ATOM   7492 O OG  . SER E 5 162 ? 141.779 176.864 112.249 1.00 44.55 ? 150 SER E OG  1 
ATOM   7493 N N   . LYS E 5 163 ? 143.336 174.789 111.126 1.00 36.05 ? 151 LYS E N   1 
ATOM   7494 C CA  . LYS E 5 163 ? 144.169 173.771 111.751 1.00 39.47 ? 151 LYS E CA  1 
ATOM   7495 C C   . LYS E 5 163 ? 144.120 172.521 110.885 1.00 41.56 ? 151 LYS E C   1 
ATOM   7496 O O   . LYS E 5 163 ? 143.089 172.224 110.273 1.00 50.13 ? 151 LYS E O   1 
ATOM   7497 C CB  . LYS E 5 163 ? 143.682 173.481 113.183 1.00 40.28 ? 151 LYS E CB  1 
ATOM   7498 C CG  . LYS E 5 163 ? 144.471 172.430 113.983 1.00 41.23 ? 151 LYS E CG  1 
ATOM   7499 C CD  . LYS E 5 163 ? 143.738 171.940 115.248 1.00 37.26 ? 151 LYS E CD  1 
ATOM   7500 C CE  . LYS E 5 163 ? 142.972 173.032 115.998 1.00 35.23 ? 151 LYS E CE  1 
ATOM   7501 N NZ  . LYS E 5 163 ? 142.510 172.567 117.333 1.00 38.34 ? 151 LYS E NZ  1 
ATOM   7502 N N   . SER E 5 164 ? 145.241 171.808 110.817 1.00 33.88 ? 152 SER E N   1 
ATOM   7503 C CA  . SER E 5 164 ? 145.314 170.611 109.992 1.00 39.88 ? 152 SER E CA  1 
ATOM   7504 C C   . SER E 5 164 ? 144.346 169.553 110.501 1.00 44.71 ? 152 SER E C   1 
ATOM   7505 O O   . SER E 5 164 ? 144.321 169.230 111.692 1.00 38.60 ? 152 SER E O   1 
ATOM   7506 C CB  . SER E 5 164 ? 146.739 170.060 109.987 1.00 43.30 ? 152 SER E CB  1 
ATOM   7507 O OG  . SER E 5 164 ? 146.818 168.851 109.257 1.00 44.79 ? 152 SER E OG  1 
ATOM   7508 N N   . LEU E 5 165 ? 143.549 169.007 109.585 1.00 41.70 ? 153 LEU E N   1 
ATOM   7509 C CA  . LEU E 5 165 ? 142.520 168.035 109.924 1.00 35.57 ? 153 LEU E CA  1 
ATOM   7510 C C   . LEU E 5 165 ? 143.054 166.611 110.010 1.00 27.94 ? 153 LEU E C   1 
ATOM   7511 O O   . LEU E 5 165 ? 142.298 165.706 110.376 1.00 33.91 ? 153 LEU E O   1 
ATOM   7512 C CB  . LEU E 5 165 ? 141.389 168.102 108.891 1.00 30.19 ? 153 LEU E CB  1 
ATOM   7513 C CG  . LEU E 5 165 ? 140.611 169.422 108.819 1.00 27.98 ? 153 LEU E CG  1 
ATOM   7514 C CD1 . LEU E 5 165 ? 139.553 169.350 107.738 1.00 24.81 ? 153 LEU E CD1 1 
ATOM   7515 C CD2 . LEU E 5 165 ? 139.976 169.797 110.146 1.00 31.63 ? 153 LEU E CD2 1 
ATOM   7516 N N   . LEU E 5 166 ? 144.322 166.388 109.680 1.00 31.92 ? 154 LEU E N   1 
ATOM   7517 C CA  . LEU E 5 166 ? 144.930 165.083 109.873 1.00 37.51 ? 154 LEU E CA  1 
ATOM   7518 C C   . LEU E 5 166 ? 145.118 164.809 111.361 1.00 38.81 ? 154 LEU E C   1 
ATOM   7519 O O   . LEU E 5 166 ? 145.588 165.662 112.118 1.00 42.60 ? 154 LEU E O   1 
ATOM   7520 C CB  . LEU E 5 166 ? 146.259 165.033 109.111 1.00 37.25 ? 154 LEU E CB  1 
ATOM   7521 C CG  . LEU E 5 166 ? 146.923 163.715 108.695 1.00 34.62 ? 154 LEU E CG  1 
ATOM   7522 C CD1 . LEU E 5 166 ? 147.947 163.995 107.621 1.00 40.90 ? 154 LEU E CD1 1 
ATOM   7523 C CD2 . LEU E 5 166 ? 147.618 163.034 109.852 1.00 35.40 ? 154 LEU E CD2 1 
ATOM   7524 N N   . HIS E 5 167 ? 144.738 163.599 111.770 1.00 36.19 ? 155 HIS E N   1 
ATOM   7525 C CA  . HIS E 5 167 ? 144.792 163.153 113.154 1.00 33.66 ? 155 HIS E CA  1 
ATOM   7526 C C   . HIS E 5 167 ? 145.763 161.986 113.254 1.00 41.77 ? 155 HIS E C   1 
ATOM   7527 O O   . HIS E 5 167 ? 146.055 161.313 112.267 1.00 43.69 ? 155 HIS E O   1 
ATOM   7528 C CB  . HIS E 5 167 ? 143.390 162.758 113.662 1.00 31.02 ? 155 HIS E CB  1 
ATOM   7529 C CG  . HIS E 5 167 ? 143.265 162.724 115.156 1.00 37.84 ? 155 HIS E CG  1 
ATOM   7530 N ND1 . HIS E 5 167 ? 143.671 161.645 115.911 1.00 41.51 ? 155 HIS E ND1 1 
ATOM   7531 C CD2 . HIS E 5 167 ? 142.789 163.637 116.035 1.00 39.65 ? 155 HIS E CD2 1 
ATOM   7532 C CE1 . HIS E 5 167 ? 143.442 161.891 117.188 1.00 39.21 ? 155 HIS E CE1 1 
ATOM   7533 N NE2 . HIS E 5 167 ? 142.909 163.095 117.291 1.00 40.37 ? 155 HIS E NE2 1 
ATOM   7534 N N   . SER E 5 168 ? 146.272 161.760 114.467 1.00 46.32 ? 156 SER E N   1 
ATOM   7535 C CA  . SER E 5 168 ? 147.328 160.770 114.669 1.00 42.89 ? 156 SER E CA  1 
ATOM   7536 C C   . SER E 5 168 ? 146.880 159.359 114.304 1.00 49.04 ? 156 SER E C   1 
ATOM   7537 O O   . SER E 5 168 ? 147.718 158.518 113.964 1.00 51.15 ? 156 SER E O   1 
ATOM   7538 C CB  . SER E 5 168 ? 147.808 160.808 116.118 1.00 44.38 ? 156 SER E CB  1 
ATOM   7539 O OG  . SER E 5 168 ? 148.977 160.023 116.274 1.00 53.41 ? 156 SER E OG  1 
ATOM   7540 N N   . ASN E 5 169 ? 145.576 159.074 114.369 1.00 42.43 ? 157 ASN E N   1 
ATOM   7541 C CA  . ASN E 5 169 ? 145.080 157.795 113.866 1.00 36.87 ? 157 ASN E CA  1 
ATOM   7542 C C   . ASN E 5 169 ? 145.287 157.652 112.360 1.00 40.33 ? 157 ASN E C   1 
ATOM   7543 O O   . ASN E 5 169 ? 145.312 156.527 111.846 1.00 44.24 ? 157 ASN E O   1 
ATOM   7544 C CB  . ASN E 5 169 ? 143.600 157.621 114.220 1.00 37.02 ? 157 ASN E CB  1 
ATOM   7545 C CG  . ASN E 5 169 ? 142.716 158.706 113.631 1.00 43.38 ? 157 ASN E CG  1 
ATOM   7546 O OD1 . ASN E 5 169 ? 142.594 158.838 112.415 1.00 44.92 ? 157 ASN E OD1 1 
ATOM   7547 N ND2 . ASN E 5 169 ? 142.073 159.474 114.499 1.00 44.64 ? 157 ASN E ND2 1 
ATOM   7548 N N   . GLY E 5 170 ? 145.426 158.769 111.641 1.00 40.59 ? 158 GLY E N   1 
ATOM   7549 C CA  . GLY E 5 170 ? 145.676 158.782 110.215 1.00 38.84 ? 158 GLY E CA  1 
ATOM   7550 C C   . GLY E 5 170 ? 144.516 159.242 109.362 1.00 36.79 ? 158 GLY E C   1 
ATOM   7551 O O   . GLY E 5 170 ? 144.721 159.534 108.177 1.00 37.91 ? 158 GLY E O   1 
ATOM   7552 N N   . ASN E 5 171 ? 143.310 159.324 109.918 1.00 34.29 ? 159 ASN E N   1 
ATOM   7553 C CA  . ASN E 5 171 ? 142.181 159.864 109.177 1.00 34.10 ? 159 ASN E CA  1 
ATOM   7554 C C   . ASN E 5 171 ? 142.259 161.383 109.122 1.00 28.84 ? 159 ASN E C   1 
ATOM   7555 O O   . ASN E 5 171 ? 142.675 162.032 110.084 1.00 37.21 ? 159 ASN E O   1 
ATOM   7556 C CB  . ASN E 5 171 ? 140.864 159.437 109.824 1.00 30.82 ? 159 ASN E CB  1 
ATOM   7557 C CG  . ASN E 5 171 ? 140.743 157.937 109.972 1.00 32.37 ? 159 ASN E CG  1 
ATOM   7558 O OD1 . ASN E 5 171 ? 140.757 157.407 111.080 1.00 27.82 ? 159 ASN E OD1 1 
ATOM   7559 N ND2 . ASN E 5 171 ? 140.622 157.241 108.851 1.00 35.82 ? 159 ASN E ND2 1 
ATOM   7560 N N   . THR E 5 172 ? 141.860 161.945 107.982 1.00 23.26 ? 160 THR E N   1 
ATOM   7561 C CA  . THR E 5 172 ? 141.684 163.383 107.807 1.00 28.10 ? 160 THR E CA  1 
ATOM   7562 C C   . THR E 5 172 ? 140.194 163.645 107.659 1.00 29.20 ? 160 THR E C   1 
ATOM   7563 O O   . THR E 5 172 ? 139.585 163.218 106.675 1.00 32.93 ? 160 THR E O   1 
ATOM   7564 C CB  . THR E 5 172 ? 142.436 163.904 106.583 1.00 30.90 ? 160 THR E CB  1 
ATOM   7565 O OG1 . THR E 5 172 ? 141.642 163.696 105.411 1.00 34.65 ? 160 THR E OG1 1 
ATOM   7566 C CG2 . THR E 5 172 ? 143.764 163.191 106.416 1.00 36.74 ? 160 THR E CG2 1 
ATOM   7567 N N   . TYR E 5 173 ? 139.616 164.355 108.624 1.00 20.43 ? 161 TYR E N   1 
ATOM   7568 C CA  . TYR E 5 173 ? 138.163 164.461 108.747 1.00 17.89 ? 161 TYR E CA  1 
ATOM   7569 C C   . TYR E 5 173 ? 137.648 165.663 107.957 1.00 21.42 ? 161 TYR E C   1 
ATOM   7570 O O   . TYR E 5 173 ? 137.344 166.723 108.502 1.00 27.46 ? 161 TYR E O   1 
ATOM   7571 C CB  . TYR E 5 173 ? 137.772 164.562 110.213 1.00 23.59 ? 161 TYR E CB  1 
ATOM   7572 C CG  . TYR E 5 173 ? 138.306 163.436 111.058 1.00 27.11 ? 161 TYR E CG  1 
ATOM   7573 C CD1 . TYR E 5 173 ? 137.728 162.182 111.021 1.00 27.64 ? 161 TYR E CD1 1 
ATOM   7574 C CD2 . TYR E 5 173 ? 139.397 163.628 111.887 1.00 26.01 ? 161 TYR E CD2 1 
ATOM   7575 C CE1 . TYR E 5 173 ? 138.217 161.153 111.791 1.00 28.48 ? 161 TYR E CE1 1 
ATOM   7576 C CE2 . TYR E 5 173 ? 139.891 162.606 112.660 1.00 29.41 ? 161 TYR E CE2 1 
ATOM   7577 C CZ  . TYR E 5 173 ? 139.296 161.370 112.611 1.00 31.54 ? 161 TYR E CZ  1 
ATOM   7578 O OH  . TYR E 5 173 ? 139.786 160.340 113.378 1.00 43.94 ? 161 TYR E OH  1 
ATOM   7579 N N   . LEU E 5 174 ? 137.552 165.471 106.642 1.00 22.66 ? 162 LEU E N   1 
ATOM   7580 C CA  . LEU E 5 174 ? 136.925 166.428 105.738 1.00 23.42 ? 162 LEU E CA  1 
ATOM   7581 C C   . LEU E 5 174 ? 135.780 165.741 105.013 1.00 26.04 ? 162 LEU E C   1 
ATOM   7582 O O   . LEU E 5 174 ? 135.928 164.612 104.536 1.00 32.01 ? 162 LEU E O   1 
ATOM   7583 C CB  . LEU E 5 174 ? 137.925 166.995 104.730 1.00 19.22 ? 162 LEU E CB  1 
ATOM   7584 C CG  . LEU E 5 174 ? 137.405 168.160 103.878 1.00 20.71 ? 162 LEU E CG  1 
ATOM   7585 C CD1 . LEU E 5 174 ? 137.734 169.490 104.528 1.00 28.74 ? 162 LEU E CD1 1 
ATOM   7586 C CD2 . LEU E 5 174 ? 137.973 168.076 102.480 1.00 25.79 ? 162 LEU E CD2 1 
ATOM   7587 N N   . TYR E 5 175 ? 134.648 166.436 104.932 1.00 20.82 ? 163 TYR E N   1 
ATOM   7588 C CA  . TYR E 5 175 ? 133.423 165.947 104.317 1.00 19.18 ? 163 TYR E CA  1 
ATOM   7589 C C   . TYR E 5 175 ? 132.927 166.969 103.309 1.00 21.50 ? 163 TYR E C   1 
ATOM   7590 O O   . TYR E 5 175 ? 132.886 168.167 103.600 1.00 22.65 ? 163 TYR E O   1 
ATOM   7591 C CB  . TYR E 5 175 ? 132.327 165.671 105.367 1.00 21.50 ? 163 TYR E CB  1 
ATOM   7592 C CG  . TYR E 5 175 ? 132.675 164.621 106.403 1.00 19.83 ? 163 TYR E CG  1 
ATOM   7593 C CD1 . TYR E 5 175 ? 133.623 164.851 107.386 1.00 18.70 ? 163 TYR E CD1 1 
ATOM   7594 C CD2 . TYR E 5 175 ? 132.022 163.402 106.409 1.00 21.35 ? 163 TYR E CD2 1 
ATOM   7595 C CE1 . TYR E 5 175 ? 133.935 163.892 108.306 1.00 16.05 ? 163 TYR E CE1 1 
ATOM   7596 C CE2 . TYR E 5 175 ? 132.321 162.443 107.339 1.00 16.37 ? 163 TYR E CE2 1 
ATOM   7597 C CZ  . TYR E 5 175 ? 133.276 162.695 108.284 1.00 17.13 ? 163 TYR E CZ  1 
ATOM   7598 O OH  . TYR E 5 175 ? 133.585 161.742 109.213 1.00 31.58 ? 163 TYR E OH  1 
ATOM   7599 N N   . TRP E 5 176 ? 132.554 166.487 102.126 1.00 22.58 ? 164 TRP E N   1 
ATOM   7600 C CA  . TRP E 5 176 ? 132.008 167.311 101.056 1.00 24.75 ? 164 TRP E CA  1 
ATOM   7601 C C   . TRP E 5 176 ? 130.527 167.005 100.916 1.00 19.08 ? 164 TRP E C   1 
ATOM   7602 O O   . TRP E 5 176 ? 130.131 165.836 100.919 1.00 12.73 ? 164 TRP E O   1 
ATOM   7603 C CB  . TRP E 5 176 ? 132.729 167.052 99.731  1.00 37.57 ? 164 TRP E CB  1 
ATOM   7604 C CG  . TRP E 5 176 ? 134.080 167.685 99.647  1.00 30.02 ? 164 TRP E CG  1 
ATOM   7605 C CD1 . TRP E 5 176 ? 135.283 167.076 99.843  1.00 28.66 ? 164 TRP E CD1 1 
ATOM   7606 C CD2 . TRP E 5 176 ? 134.369 169.053 99.341  1.00 25.57 ? 164 TRP E CD2 1 
ATOM   7607 N NE1 . TRP E 5 176 ? 136.302 167.979 99.681  1.00 29.16 ? 164 TRP E NE1 1 
ATOM   7608 C CE2 . TRP E 5 176 ? 135.767 169.201 99.372  1.00 28.70 ? 164 TRP E CE2 1 
ATOM   7609 C CE3 . TRP E 5 176 ? 133.581 170.167 99.044  1.00 26.90 ? 164 TRP E CE3 1 
ATOM   7610 C CZ2 . TRP E 5 176 ? 136.392 170.416 99.118  1.00 32.64 ? 164 TRP E CZ2 1 
ATOM   7611 C CZ3 . TRP E 5 176 ? 134.204 171.371 98.791  1.00 26.86 ? 164 TRP E CZ3 1 
ATOM   7612 C CH2 . TRP E 5 176 ? 135.594 171.486 98.830  1.00 28.72 ? 164 TRP E CH2 1 
ATOM   7613 N N   . PHE E 5 177 ? 129.720 168.059 100.799 1.00 26.64 ? 165 PHE E N   1 
ATOM   7614 C CA  . PHE E 5 177 ? 128.274 167.960 100.665 1.00 25.12 ? 165 PHE E CA  1 
ATOM   7615 C C   . PHE E 5 177 ? 127.834 168.695 99.410  1.00 22.76 ? 165 PHE E C   1 
ATOM   7616 O O   . PHE E 5 177 ? 128.495 169.632 98.963  1.00 34.49 ? 165 PHE E O   1 
ATOM   7617 C CB  . PHE E 5 177 ? 127.550 168.544 101.885 1.00 28.66 ? 165 PHE E CB  1 
ATOM   7618 C CG  . PHE E 5 177 ? 127.894 167.865 103.176 1.00 23.38 ? 165 PHE E CG  1 
ATOM   7619 C CD1 . PHE E 5 177 ? 127.316 166.655 103.506 1.00 16.16 ? 165 PHE E CD1 1 
ATOM   7620 C CD2 . PHE E 5 177 ? 128.795 168.430 104.056 1.00 24.24 ? 165 PHE E CD2 1 
ATOM   7621 C CE1 . PHE E 5 177 ? 127.627 166.027 104.685 1.00 20.51 ? 165 PHE E CE1 1 
ATOM   7622 C CE2 . PHE E 5 177 ? 129.110 167.800 105.237 1.00 20.76 ? 165 PHE E CE2 1 
ATOM   7623 C CZ  . PHE E 5 177 ? 128.526 166.597 105.551 1.00 22.88 ? 165 PHE E CZ  1 
ATOM   7624 N N   . LEU E 5 178 ? 126.723 168.239 98.837  1.00 29.14 ? 166 LEU E N   1 
ATOM   7625 C CA  . LEU E 5 178 ? 126.095 168.860 97.678  1.00 33.25 ? 166 LEU E CA  1 
ATOM   7626 C C   . LEU E 5 178 ? 124.649 169.192 98.000  1.00 36.68 ? 166 LEU E C   1 
ATOM   7627 O O   . LEU E 5 178 ? 123.872 168.301 98.353  1.00 47.72 ? 166 LEU E O   1 
ATOM   7628 C CB  . LEU E 5 178 ? 126.149 167.941 96.456  1.00 31.64 ? 166 LEU E CB  1 
ATOM   7629 C CG  . LEU E 5 178 ? 125.657 168.526 95.126  1.00 36.10 ? 166 LEU E CG  1 
ATOM   7630 C CD1 . LEU E 5 178 ? 126.796 169.070 94.333  1.00 41.38 ? 166 LEU E CD1 1 
ATOM   7631 C CD2 . LEU E 5 178 ? 124.927 167.467 94.326  1.00 40.49 ? 166 LEU E CD2 1 
ATOM   7632 N N   . GLN E 5 179 ? 124.293 170.464 97.844  1.00 28.36 ? 167 GLN E N   1 
ATOM   7633 C CA  . GLN E 5 179 ? 122.916 170.933 97.925  1.00 33.86 ? 167 GLN E CA  1 
ATOM   7634 C C   . GLN E 5 179 ? 122.491 171.387 96.536  1.00 38.21 ? 167 GLN E C   1 
ATOM   7635 O O   . GLN E 5 179 ? 122.854 172.483 96.098  1.00 38.23 ? 167 GLN E O   1 
ATOM   7636 C CB  . GLN E 5 179 ? 122.781 172.066 98.936  1.00 32.83 ? 167 GLN E CB  1 
ATOM   7637 C CG  . GLN E 5 179 ? 121.424 172.763 98.897  1.00 34.97 ? 167 GLN E CG  1 
ATOM   7638 C CD  . GLN E 5 179 ? 120.980 173.289 100.243 1.00 33.80 ? 167 GLN E CD  1 
ATOM   7639 O OE1 . GLN E 5 179 ? 119.814 173.615 100.443 1.00 36.23 ? 167 GLN E OE1 1 
ATOM   7640 N NE2 . GLN E 5 179 ? 121.917 173.374 101.179 1.00 33.09 ? 167 GLN E NE2 1 
ATOM   7641 N N   . ARG E 5 180 ? 121.724 170.549 95.853  1.00 46.46 ? 168 ARG E N   1 
ATOM   7642 C CA  . ARG E 5 180 ? 121.139 170.927 94.582  1.00 45.47 ? 168 ARG E CA  1 
ATOM   7643 C C   . ARG E 5 180 ? 120.013 171.929 94.821  1.00 47.52 ? 168 ARG E C   1 
ATOM   7644 O O   . ARG E 5 180 ? 119.541 172.073 95.951  1.00 46.49 ? 168 ARG E O   1 
ATOM   7645 C CB  . ARG E 5 180 ? 120.626 169.687 93.857  1.00 44.66 ? 168 ARG E CB  1 
ATOM   7646 C CG  . ARG E 5 180 ? 121.738 168.814 93.307  1.00 43.48 ? 168 ARG E CG  1 
ATOM   7647 C CD  . ARG E 5 180 ? 121.200 167.643 92.510  1.00 44.21 ? 168 ARG E CD  1 
ATOM   7648 N NE  . ARG E 5 180 ? 122.161 166.545 92.461  1.00 46.31 ? 168 ARG E NE  1 
ATOM   7649 C CZ  . ARG E 5 180 ? 122.282 165.579 93.365  1.00 47.98 ? 168 ARG E CZ  1 
ATOM   7650 N NH1 . ARG E 5 180 ? 121.528 165.537 94.454  1.00 50.29 ? 168 ARG E NH1 1 
ATOM   7651 N NH2 . ARG E 5 180 ? 123.198 164.633 93.179  1.00 45.64 ? 168 ARG E NH2 1 
ATOM   7652 N N   . PRO E 5 181 ? 119.586 172.665 93.787  1.00 56.46 ? 169 PRO E N   1 
ATOM   7653 C CA  . PRO E 5 181 ? 118.559 173.694 94.005  1.00 53.80 ? 169 PRO E CA  1 
ATOM   7654 C C   . PRO E 5 181 ? 117.244 173.100 94.488  1.00 56.95 ? 169 PRO E C   1 
ATOM   7655 O O   . PRO E 5 181 ? 116.664 172.219 93.850  1.00 54.49 ? 169 PRO E O   1 
ATOM   7656 C CB  . PRO E 5 181 ? 118.402 174.340 92.623  1.00 55.41 ? 169 PRO E CB  1 
ATOM   7657 C CG  . PRO E 5 181 ? 119.639 174.000 91.893  1.00 55.56 ? 169 PRO E CG  1 
ATOM   7658 C CD  . PRO E 5 181 ? 120.028 172.649 92.380  1.00 56.45 ? 169 PRO E CD  1 
ATOM   7659 N N   . GLY E 5 182 ? 116.778 173.595 95.634  1.00 60.28 ? 170 GLY E N   1 
ATOM   7660 C CA  . GLY E 5 182 ? 115.539 173.113 96.209  1.00 59.50 ? 170 GLY E CA  1 
ATOM   7661 C C   . GLY E 5 182 ? 115.610 171.736 96.825  1.00 59.09 ? 170 GLY E C   1 
ATOM   7662 O O   . GLY E 5 182 ? 114.579 171.062 96.906  1.00 60.98 ? 170 GLY E O   1 
ATOM   7663 N N   . GLN E 5 183 ? 116.793 171.297 97.257  1.00 48.19 ? 171 GLN E N   1 
ATOM   7664 C CA  . GLN E 5 183 ? 117.003 169.971 97.820  1.00 43.88 ? 171 GLN E CA  1 
ATOM   7665 C C   . GLN E 5 183 ? 117.856 170.078 99.075  1.00 45.12 ? 171 GLN E C   1 
ATOM   7666 O O   . GLN E 5 183 ? 118.569 171.064 99.277  1.00 44.13 ? 171 GLN E O   1 
ATOM   7667 C CB  . GLN E 5 183 ? 117.687 169.037 96.815  1.00 39.29 ? 171 GLN E CB  1 
ATOM   7668 C CG  . GLN E 5 183 ? 116.732 168.426 95.787  1.00 41.83 ? 171 GLN E CG  1 
ATOM   7669 C CD  . GLN E 5 183 ? 117.335 167.276 94.987  1.00 48.18 ? 171 GLN E CD  1 
ATOM   7670 O OE1 . GLN E 5 183 ? 117.227 167.248 93.761  1.00 50.24 ? 171 GLN E OE1 1 
ATOM   7671 N NE2 . GLN E 5 183 ? 117.930 166.306 95.674  1.00 46.35 ? 171 GLN E NE2 1 
ATOM   7672 N N   . SER E 5 184 ? 117.766 169.058 99.924  1.00 38.46 ? 172 SER E N   1 
ATOM   7673 C CA  . SER E 5 184 ? 118.604 169.006 101.108 1.00 29.31 ? 172 SER E CA  1 
ATOM   7674 C C   . SER E 5 184 ? 120.040 168.646 100.717 1.00 28.70 ? 172 SER E C   1 
ATOM   7675 O O   . SER E 5 184 ? 120.272 168.110 99.630  1.00 33.98 ? 172 SER E O   1 
ATOM   7676 C CB  . SER E 5 184 ? 118.068 167.980 102.098 1.00 35.84 ? 172 SER E CB  1 
ATOM   7677 O OG  . SER E 5 184 ? 117.884 166.725 101.470 1.00 40.23 ? 172 SER E OG  1 
ATOM   7678 N N   . PRO E 5 185 ? 121.025 168.937 101.573 1.00 21.96 ? 173 PRO E N   1 
ATOM   7679 C CA  . PRO E 5 185 ? 122.399 168.522 101.263 1.00 23.86 ? 173 PRO E CA  1 
ATOM   7680 C C   . PRO E 5 185 ? 122.540 167.008 101.185 1.00 24.13 ? 173 PRO E C   1 
ATOM   7681 O O   . PRO E 5 185 ? 121.837 166.264 101.871 1.00 34.25 ? 173 PRO E O   1 
ATOM   7682 C CB  . PRO E 5 185 ? 123.212 169.098 102.426 1.00 25.41 ? 173 PRO E CB  1 
ATOM   7683 C CG  . PRO E 5 185 ? 122.433 170.254 102.872 1.00 27.90 ? 173 PRO E CG  1 
ATOM   7684 C CD  . PRO E 5 185 ? 121.006 169.819 102.755 1.00 29.85 ? 173 PRO E CD  1 
ATOM   7685 N N   . GLN E 5 186 ? 123.457 166.562 100.328 1.00 22.39 ? 174 GLN E N   1 
ATOM   7686 C CA  . GLN E 5 186 ? 123.785 165.153 100.152 1.00 29.57 ? 174 GLN E CA  1 
ATOM   7687 C C   . GLN E 5 186 ? 125.284 164.982 100.340 1.00 21.67 ? 174 GLN E C   1 
ATOM   7688 O O   . GLN E 5 186 ? 126.071 165.710 99.732  1.00 32.50 ? 174 GLN E O   1 
ATOM   7689 C CB  . GLN E 5 186 ? 123.329 164.658 98.763  1.00 38.61 ? 174 GLN E CB  1 
ATOM   7690 C CG  . GLN E 5 186 ? 124.100 163.469 98.135  1.00 39.04 ? 174 GLN E CG  1 
ATOM   7691 C CD  . GLN E 5 186 ? 123.611 163.133 96.746  1.00 37.88 ? 174 GLN E CD  1 
ATOM   7692 O OE1 . GLN E 5 186 ? 122.976 163.951 96.082  1.00 36.78 ? 174 GLN E OE1 1 
ATOM   7693 N NE2 . GLN E 5 186 ? 123.914 161.924 96.292  1.00 39.02 ? 174 GLN E NE2 1 
ATOM   7694 N N   . LEU E 5 187 ? 125.674 164.013 101.163 1.00 13.86 ? 175 LEU E N   1 
ATOM   7695 C CA  . LEU E 5 187 ? 127.085 163.687 101.315 1.00 20.48 ? 175 LEU E CA  1 
ATOM   7696 C C   . LEU E 5 187 ? 127.635 163.126 100.010 1.00 32.68 ? 175 LEU E C   1 
ATOM   7697 O O   . LEU E 5 187 ? 127.013 162.263 99.383  1.00 29.93 ? 175 LEU E O   1 
ATOM   7698 C CB  . LEU E 5 187 ? 127.278 162.684 102.453 1.00 15.63 ? 175 LEU E CB  1 
ATOM   7699 C CG  . LEU E 5 187 ? 128.706 162.253 102.822 1.00 18.07 ? 175 LEU E CG  1 
ATOM   7700 C CD1 . LEU E 5 187 ? 129.347 163.244 103.762 1.00 21.41 ? 175 LEU E CD1 1 
ATOM   7701 C CD2 . LEU E 5 187 ? 128.704 160.870 103.451 1.00 20.16 ? 175 LEU E CD2 1 
ATOM   7702 N N   . LEU E 5 188 ? 128.805 163.624 99.605  1.00 38.99 ? 176 LEU E N   1 
ATOM   7703 C CA  . LEU E 5 188 ? 129.568 163.099 98.478  1.00 30.10 ? 176 LEU E CA  1 
ATOM   7704 C C   . LEU E 5 188 ? 130.792 162.315 98.929  1.00 29.75 ? 176 LEU E C   1 
ATOM   7705 O O   . LEU E 5 188 ? 130.956 161.154 98.548  1.00 30.02 ? 176 LEU E O   1 
ATOM   7706 C CB  . LEU E 5 188 ? 130.014 164.239 97.554  1.00 23.84 ? 176 LEU E CB  1 
ATOM   7707 C CG  . LEU E 5 188 ? 128.949 165.150 96.946  1.00 22.71 ? 176 LEU E CG  1 
ATOM   7708 C CD1 . LEU E 5 188 ? 129.630 166.266 96.173  1.00 37.43 ? 176 LEU E CD1 1 
ATOM   7709 C CD2 . LEU E 5 188 ? 127.993 164.378 96.052  1.00 31.88 ? 176 LEU E CD2 1 
ATOM   7710 N N   . ILE E 5 189 ? 131.646 162.934 99.741  1.00 32.88 ? 177 ILE E N   1 
ATOM   7711 C CA  . ILE E 5 189 ? 132.906 162.358 100.197 1.00 23.21 ? 177 ILE E CA  1 
ATOM   7712 C C   . ILE E 5 189 ? 132.946 162.474 101.711 1.00 18.96 ? 177 ILE E C   1 
ATOM   7713 O O   . ILE E 5 189 ? 132.551 163.506 102.262 1.00 29.80 ? 177 ILE E O   1 
ATOM   7714 C CB  . ILE E 5 189 ? 134.115 163.065 99.544  1.00 28.09 ? 177 ILE E CB  1 
ATOM   7715 C CG1 . ILE E 5 189 ? 134.262 162.558 98.101  1.00 31.14 ? 177 ILE E CG1 1 
ATOM   7716 C CG2 . ILE E 5 189 ? 135.417 162.910 100.408 1.00 29.72 ? 177 ILE E CG2 1 
ATOM   7717 C CD1 . ILE E 5 189 ? 135.386 163.163 97.301  1.00 37.19 ? 177 ILE E CD1 1 
ATOM   7718 N N   . TYR E 5 190 ? 133.403 161.414 102.377 1.00 17.85 ? 178 TYR E N   1 
ATOM   7719 C CA  . TYR E 5 190 ? 133.662 161.424 103.811 1.00 18.66 ? 178 TYR E CA  1 
ATOM   7720 C C   . TYR E 5 190 ? 135.132 161.121 104.047 1.00 19.75 ? 178 TYR E C   1 
ATOM   7721 O O   . TYR E 5 190 ? 135.675 160.173 103.476 1.00 26.37 ? 178 TYR E O   1 
ATOM   7722 C CB  . TYR E 5 190 ? 132.769 160.426 104.563 1.00 15.66 ? 178 TYR E CB  1 
ATOM   7723 C CG  . TYR E 5 190 ? 132.824 158.984 104.117 1.00 23.42 ? 178 TYR E CG  1 
ATOM   7724 C CD1 . TYR E 5 190 ? 132.042 158.530 103.066 1.00 29.91 ? 178 TYR E CD1 1 
ATOM   7725 C CD2 . TYR E 5 190 ? 133.611 158.061 104.791 1.00 20.97 ? 178 TYR E CD2 1 
ATOM   7726 C CE1 . TYR E 5 190 ? 132.078 157.208 102.672 1.00 21.60 ? 178 TYR E CE1 1 
ATOM   7727 C CE2 . TYR E 5 190 ? 133.647 156.739 104.407 1.00 16.67 ? 178 TYR E CE2 1 
ATOM   7728 C CZ  . TYR E 5 190 ? 132.880 156.319 103.348 1.00 12.07 ? 178 TYR E CZ  1 
ATOM   7729 O OH  . TYR E 5 190 ? 132.916 155.002 102.962 1.00 14.30 ? 178 TYR E OH  1 
ATOM   7730 N N   . ARG E 5 191 ? 135.775 161.952 104.864 1.00 15.29 ? 179 ARG E N   1 
ATOM   7731 C CA  . ARG E 5 191 ? 137.173 161.839 105.265 1.00 11.56 ? 179 ARG E CA  1 
ATOM   7732 C C   . ARG E 5 191 ? 138.133 162.016 104.090 1.00 22.16 ? 179 ARG E C   1 
ATOM   7733 O O   . ARG E 5 191 ? 139.150 161.317 104.010 1.00 27.94 ? 179 ARG E O   1 
ATOM   7734 C CB  . ARG E 5 191 ? 137.433 160.513 105.994 1.00 23.47 ? 179 ARG E CB  1 
ATOM   7735 C CG  . ARG E 5 191 ? 136.757 160.453 107.353 1.00 19.18 ? 179 ARG E CG  1 
ATOM   7736 C CD  . ARG E 5 191 ? 137.239 159.282 108.176 1.00 23.32 ? 179 ARG E CD  1 
ATOM   7737 N NE  . ARG E 5 191 ? 136.130 158.617 108.855 1.00 19.79 ? 179 ARG E NE  1 
ATOM   7738 C CZ  . ARG E 5 191 ? 135.409 157.612 108.370 1.00 13.90 ? 179 ARG E CZ  1 
ATOM   7739 N NH1 . ARG E 5 191 ? 135.628 157.106 107.167 1.00 18.60 ? 179 ARG E NH1 1 
ATOM   7740 N NH2 . ARG E 5 191 ? 134.431 157.105 109.112 1.00 19.76 ? 179 ARG E NH2 1 
ATOM   7741 N N   . MET E 5 192 ? 137.801 162.907 103.151 1.00 27.07 ? 180 MET E N   1 
ATOM   7742 C CA  . MET E 5 192 ? 138.686 163.503 102.148 1.00 27.90 ? 180 MET E CA  1 
ATOM   7743 C C   . MET E 5 192 ? 139.035 162.585 100.976 1.00 32.79 ? 180 MET E C   1 
ATOM   7744 O O   . MET E 5 192 ? 139.457 163.087 99.929  1.00 42.02 ? 180 MET E O   1 
ATOM   7745 C CB  . MET E 5 192 ? 139.982 163.983 102.836 1.00 26.50 ? 180 MET E CB  1 
ATOM   7746 C CG  . MET E 5 192 ? 141.040 164.682 101.973 1.00 32.52 ? 180 MET E CG  1 
ATOM   7747 S SD  . MET E 5 192 ? 142.609 164.749 102.844 1.00 60.61 ? 180 MET E SD  1 
ATOM   7748 C CE  . MET E 5 192 ? 143.428 163.331 102.121 1.00 35.98 ? 180 MET E CE  1 
ATOM   7749 N N   . SER E 5 193 ? 138.807 161.274 101.087 1.00 27.79 ? 181 SER E N   1 
ATOM   7750 C CA  . SER E 5 193 ? 139.091 160.343 99.998  1.00 24.65 ? 181 SER E CA  1 
ATOM   7751 C C   . SER E 5 193 ? 138.003 159.314 99.760  1.00 29.27 ? 181 SER E C   1 
ATOM   7752 O O   . SER E 5 193 ? 137.832 158.876 98.621  1.00 31.34 ? 181 SER E O   1 
ATOM   7753 C CB  . SER E 5 193 ? 140.412 159.608 100.266 1.00 27.03 ? 181 SER E CB  1 
ATOM   7754 O OG  . SER E 5 193 ? 140.512 159.228 101.625 1.00 29.87 ? 181 SER E OG  1 
ATOM   7755 N N   . ASN E 5 194 ? 137.262 158.922 100.789 1.00 21.05 ? 182 ASN E N   1 
ATOM   7756 C CA  . ASN E 5 194 ? 136.241 157.903 100.620 1.00 21.99 ? 182 ASN E CA  1 
ATOM   7757 C C   . ASN E 5 194 ? 135.004 158.516 99.980  1.00 22.89 ? 182 ASN E C   1 
ATOM   7758 O O   . ASN E 5 194 ? 134.698 159.691 100.184 1.00 27.60 ? 182 ASN E O   1 
ATOM   7759 C CB  . ASN E 5 194 ? 135.897 157.273 101.964 1.00 25.51 ? 182 ASN E CB  1 
ATOM   7760 C CG  . ASN E 5 194 ? 137.128 156.830 102.728 1.00 23.83 ? 182 ASN E CG  1 
ATOM   7761 O OD1 . ASN E 5 194 ? 137.302 157.169 103.896 1.00 14.33 ? 182 ASN E OD1 1 
ATOM   7762 N ND2 . ASN E 5 194 ? 137.992 156.070 102.068 1.00 28.67 ? 182 ASN E ND2 1 
ATOM   7763 N N   . LEU E 5 195 ? 134.290 157.703 99.206  1.00 29.67 ? 183 LEU E N   1 
ATOM   7764 C CA  . LEU E 5 195 ? 133.151 158.141 98.410  1.00 24.27 ? 183 LEU E CA  1 
ATOM   7765 C C   . LEU E 5 195 ? 131.881 157.535 98.984  1.00 32.34 ? 183 LEU E C   1 
ATOM   7766 O O   . LEU E 5 195 ? 131.823 156.327 99.233  1.00 40.75 ? 183 LEU E O   1 
ATOM   7767 C CB  . LEU E 5 195 ? 133.330 157.728 96.944  1.00 28.78 ? 183 LEU E CB  1 
ATOM   7768 C CG  . LEU E 5 195 ? 132.587 158.473 95.829  1.00 33.65 ? 183 LEU E CG  1 
ATOM   7769 C CD1 . LEU E 5 195 ? 132.864 159.971 95.832  1.00 38.11 ? 183 LEU E CD1 1 
ATOM   7770 C CD2 . LEU E 5 195 ? 132.965 157.867 94.489  1.00 36.54 ? 183 LEU E CD2 1 
ATOM   7771 N N   . ALA E 5 196 ? 130.872 158.373 99.198  1.00 33.02 ? 184 ALA E N   1 
ATOM   7772 C CA  . ALA E 5 196 ? 129.620 157.907 99.770  1.00 34.14 ? 184 ALA E CA  1 
ATOM   7773 C C   . ALA E 5 196 ? 128.903 156.974 98.804  1.00 31.30 ? 184 ALA E C   1 
ATOM   7774 O O   . ALA E 5 196 ? 129.059 157.065 97.584  1.00 36.51 ? 184 ALA E O   1 
ATOM   7775 C CB  . ALA E 5 196 ? 128.720 159.090 100.118 1.00 33.62 ? 184 ALA E CB  1 
ATOM   7776 N N   . SER E 5 197 ? 128.116 156.060 99.366  1.00 31.85 ? 185 SER E N   1 
ATOM   7777 C CA  . SER E 5 197 ? 127.355 155.128 98.547  1.00 37.53 ? 185 SER E CA  1 
ATOM   7778 C C   . SER E 5 197 ? 126.285 155.869 97.757  1.00 39.54 ? 185 SER E C   1 
ATOM   7779 O O   . SER E 5 197 ? 125.676 156.824 98.246  1.00 38.49 ? 185 SER E O   1 
ATOM   7780 C CB  . SER E 5 197 ? 126.712 154.056 99.423  1.00 41.96 ? 185 SER E CB  1 
ATOM   7781 O OG  . SER E 5 197 ? 125.457 154.492 99.915  1.00 46.29 ? 185 SER E OG  1 
ATOM   7782 N N   . GLY E 5 198 ? 126.055 155.418 96.526  1.00 43.56 ? 186 GLY E N   1 
ATOM   7783 C CA  . GLY E 5 198 ? 125.110 156.068 95.643  1.00 44.41 ? 186 GLY E CA  1 
ATOM   7784 C C   . GLY E 5 198 ? 125.639 157.286 94.922  1.00 46.16 ? 186 GLY E C   1 
ATOM   7785 O O   . GLY E 5 198 ? 124.848 157.995 94.289  1.00 47.01 ? 186 GLY E O   1 
ATOM   7786 N N   . VAL E 5 199 ? 126.938 157.544 94.990  1.00 41.03 ? 187 VAL E N   1 
ATOM   7787 C CA  . VAL E 5 199 ? 127.583 158.686 94.349  1.00 43.94 ? 187 VAL E CA  1 
ATOM   7788 C C   . VAL E 5 199 ? 128.398 158.149 93.173  1.00 48.12 ? 187 VAL E C   1 
ATOM   7789 O O   . VAL E 5 199 ? 129.104 157.150 93.343  1.00 48.39 ? 187 VAL E O   1 
ATOM   7790 C CB  . VAL E 5 199 ? 128.491 159.453 95.331  1.00 38.07 ? 187 VAL E CB  1 
ATOM   7791 C CG1 . VAL E 5 199 ? 129.101 160.695 94.679  1.00 37.03 ? 187 VAL E CG1 1 
ATOM   7792 C CG2 . VAL E 5 199 ? 127.707 159.840 96.581  1.00 39.62 ? 187 VAL E CG2 1 
ATOM   7793 N N   . PRO E 5 200 ? 128.338 158.757 91.987  1.00 56.84 ? 188 PRO E N   1 
ATOM   7794 C CA  . PRO E 5 200 ? 129.129 158.228 90.871  1.00 55.18 ? 188 PRO E CA  1 
ATOM   7795 C C   . PRO E 5 200 ? 130.622 158.443 91.067  1.00 55.22 ? 188 PRO E C   1 
ATOM   7796 O O   . PRO E 5 200 ? 131.069 159.270 91.865  1.00 55.25 ? 188 PRO E O   1 
ATOM   7797 C CB  . PRO E 5 200 ? 128.602 159.011 89.666  1.00 55.25 ? 188 PRO E CB  1 
ATOM   7798 C CG  . PRO E 5 200 ? 128.172 160.289 90.241  1.00 54.00 ? 188 PRO E CG  1 
ATOM   7799 C CD  . PRO E 5 200 ? 127.545 159.922 91.543  1.00 51.40 ? 188 PRO E CD  1 
ATOM   7800 N N   . ASP E 5 201 ? 131.399 157.675 90.300  1.00 61.38 ? 189 ASP E N   1 
ATOM   7801 C CA  . ASP E 5 201 ? 132.856 157.690 90.425  1.00 63.39 ? 189 ASP E CA  1 
ATOM   7802 C C   . ASP E 5 201 ? 133.496 158.990 89.944  1.00 64.60 ? 189 ASP E C   1 
ATOM   7803 O O   . ASP E 5 201 ? 134.703 159.171 90.136  1.00 58.67 ? 189 ASP E O   1 
ATOM   7804 C CB  . ASP E 5 201 ? 133.465 156.513 89.642  1.00 64.03 ? 189 ASP E CB  1 
ATOM   7805 C CG  . ASP E 5 201 ? 134.579 155.779 90.397  1.00 65.29 ? 189 ASP E CG  1 
ATOM   7806 O OD1 . ASP E 5 201 ? 134.962 156.167 91.521  1.00 66.98 ? 189 ASP E OD1 1 
ATOM   7807 O OD2 . ASP E 5 201 ? 135.106 154.796 89.832  1.00 61.77 ? 189 ASP E OD2 1 
ATOM   7808 N N   . ARG E 5 202 ? 132.734 159.875 89.293  1.00 61.12 ? 190 ARG E N   1 
ATOM   7809 C CA  . ARG E 5 202 ? 133.304 161.108 88.757  1.00 59.71 ? 190 ARG E CA  1 
ATOM   7810 C C   . ARG E 5 202 ? 133.884 161.982 89.867  1.00 65.43 ? 190 ARG E C   1 
ATOM   7811 O O   . ARG E 5 202 ? 134.943 162.597 89.691  1.00 63.74 ? 190 ARG E O   1 
ATOM   7812 C CB  . ARG E 5 202 ? 132.233 161.849 87.947  1.00 58.26 ? 190 ARG E CB  1 
ATOM   7813 C CG  . ARG E 5 202 ? 131.135 162.548 88.764  1.00 60.03 ? 190 ARG E CG  1 
ATOM   7814 C CD  . ARG E 5 202 ? 130.088 163.230 87.898  1.00 59.54 ? 190 ARG E CD  1 
ATOM   7815 N NE  . ARG E 5 202 ? 129.405 162.260 87.041  1.00 65.56 ? 190 ARG E NE  1 
ATOM   7816 C CZ  . ARG E 5 202 ? 128.092 162.117 86.882  1.00 64.93 ? 190 ARG E CZ  1 
ATOM   7817 N NH1 . ARG E 5 202 ? 127.213 162.888 87.505  1.00 62.34 ? 190 ARG E NH1 1 
ATOM   7818 N NH2 . ARG E 5 202 ? 127.643 161.162 86.073  1.00 62.89 ? 190 ARG E NH2 1 
ATOM   7819 N N   . PHE E 5 203 ? 133.209 162.049 91.013  1.00 56.46 ? 191 PHE E N   1 
ATOM   7820 C CA  . PHE E 5 203 ? 133.737 162.796 92.145  1.00 49.66 ? 191 PHE E CA  1 
ATOM   7821 C C   . PHE E 5 203 ? 134.946 162.089 92.740  1.00 50.01 ? 191 PHE E C   1 
ATOM   7822 O O   . PHE E 5 203 ? 134.961 160.864 92.889  1.00 52.75 ? 191 PHE E O   1 
ATOM   7823 C CB  . PHE E 5 203 ? 132.663 162.978 93.215  1.00 45.55 ? 191 PHE E CB  1 
ATOM   7824 C CG  . PHE E 5 203 ? 131.503 163.820 92.777  1.00 46.42 ? 191 PHE E CG  1 
ATOM   7825 C CD1 . PHE E 5 203 ? 131.553 165.193 92.901  1.00 44.54 ? 191 PHE E CD1 1 
ATOM   7826 C CD2 . PHE E 5 203 ? 130.366 163.241 92.249  1.00 49.42 ? 191 PHE E CD2 1 
ATOM   7827 C CE1 . PHE E 5 203 ? 130.493 165.977 92.507  1.00 41.79 ? 191 PHE E CE1 1 
ATOM   7828 C CE2 . PHE E 5 203 ? 129.301 164.018 91.851  1.00 46.80 ? 191 PHE E CE2 1 
ATOM   7829 C CZ  . PHE E 5 203 ? 129.364 165.389 91.985  1.00 41.70 ? 191 PHE E CZ  1 
ATOM   7830 N N   . SER E 5 204 ? 135.968 162.873 93.069  1.00 40.48 ? 192 SER E N   1 
ATOM   7831 C CA  . SER E 5 204 ? 137.146 162.378 93.762  1.00 43.59 ? 192 SER E CA  1 
ATOM   7832 C C   . SER E 5 204 ? 137.665 163.477 94.673  1.00 46.25 ? 192 SER E C   1 
ATOM   7833 O O   . SER E 5 204 ? 137.567 164.664 94.351  1.00 51.92 ? 192 SER E O   1 
ATOM   7834 C CB  . SER E 5 204 ? 138.240 161.945 92.780  1.00 45.34 ? 192 SER E CB  1 
ATOM   7835 O OG  . SER E 5 204 ? 138.713 163.047 92.027  1.00 48.45 ? 192 SER E OG  1 
ATOM   7836 N N   . GLY E 5 205 ? 138.224 163.066 95.809  1.00 37.64 ? 193 GLY E N   1 
ATOM   7837 C CA  . GLY E 5 205 ? 138.741 163.988 96.802  1.00 35.08 ? 193 GLY E CA  1 
ATOM   7838 C C   . GLY E 5 205 ? 140.220 163.791 97.049  1.00 38.34 ? 193 GLY E C   1 
ATOM   7839 O O   . GLY E 5 205 ? 140.646 162.728 97.510  1.00 43.19 ? 193 GLY E O   1 
ATOM   7840 N N   . SER E 5 206 ? 141.004 164.819 96.739  1.00 44.22 ? 194 SER E N   1 
ATOM   7841 C CA  . SER E 5 206 ? 142.436 164.858 97.000  1.00 51.58 ? 194 SER E CA  1 
ATOM   7842 C C   . SER E 5 206 ? 142.700 165.989 97.978  1.00 47.43 ? 194 SER E C   1 
ATOM   7843 O O   . SER E 5 206 ? 142.125 167.072 97.844  1.00 52.68 ? 194 SER E O   1 
ATOM   7844 C CB  . SER E 5 206 ? 143.228 165.077 95.709  1.00 53.05 ? 194 SER E CB  1 
ATOM   7845 O OG  . SER E 5 206 ? 144.582 165.393 95.988  1.00 51.36 ? 194 SER E OG  1 
ATOM   7846 N N   . GLY E 5 207 ? 143.541 165.736 98.968  1.00 39.58 ? 195 GLY E N   1 
ATOM   7847 C CA  . GLY E 5 207 ? 143.848 166.750 99.956  1.00 38.00 ? 195 GLY E CA  1 
ATOM   7848 C C   . GLY E 5 207 ? 145.097 166.422 100.741 1.00 40.96 ? 195 GLY E C   1 
ATOM   7849 O O   . GLY E 5 207 ? 145.402 165.261 101.019 1.00 44.55 ? 195 GLY E O   1 
ATOM   7850 N N   . SER E 5 208 ? 145.820 167.477 101.092 1.00 42.97 ? 196 SER E N   1 
ATOM   7851 C CA  . SER E 5 208 ? 146.847 167.454 102.120 1.00 45.89 ? 196 SER E CA  1 
ATOM   7852 C C   . SER E 5 208 ? 146.233 168.049 103.374 1.00 45.96 ? 196 SER E C   1 
ATOM   7853 O O   . SER E 5 208 ? 145.149 168.632 103.314 1.00 55.12 ? 196 SER E O   1 
ATOM   7854 C CB  . SER E 5 208 ? 148.073 168.262 101.702 1.00 50.89 ? 196 SER E CB  1 
ATOM   7855 O OG  . SER E 5 208 ? 147.683 169.439 101.016 1.00 46.64 ? 196 SER E OG  1 
ATOM   7856 N N   . GLY E 5 209 ? 146.896 167.870 104.512 1.00 43.55 ? 197 GLY E N   1 
ATOM   7857 C CA  . GLY E 5 209 ? 146.479 168.572 105.708 1.00 43.34 ? 197 GLY E CA  1 
ATOM   7858 C C   . GLY E 5 209 ? 146.471 170.068 105.468 1.00 46.67 ? 197 GLY E C   1 
ATOM   7859 O O   . GLY E 5 209 ? 147.408 170.596 104.863 1.00 47.71 ? 197 GLY E O   1 
ATOM   7860 N N   . THR E 5 210 ? 145.391 170.744 105.870 1.00 43.48 ? 198 THR E N   1 
ATOM   7861 C CA  . THR E 5 210 ? 145.154 172.188 105.816 1.00 45.27 ? 198 THR E CA  1 
ATOM   7862 C C   . THR E 5 210 ? 144.786 172.666 104.398 1.00 43.69 ? 198 THR E C   1 
ATOM   7863 O O   . THR E 5 210 ? 144.271 173.773 104.254 1.00 49.15 ? 198 THR E O   1 
ATOM   7864 C CB  . THR E 5 210 ? 146.357 173.002 106.351 1.00 51.05 ? 198 THR E CB  1 
ATOM   7865 O OG1 . THR E 5 210 ? 146.553 172.680 107.732 1.00 54.92 ? 198 THR E OG1 1 
ATOM   7866 C CG2 . THR E 5 210 ? 146.155 174.506 106.279 1.00 48.83 ? 198 THR E CG2 1 
ATOM   7867 N N   . ALA E 5 211 ? 144.908 171.822 103.371 1.00 30.49 ? 199 ALA E N   1 
ATOM   7868 C CA  . ALA E 5 211 ? 144.616 172.203 101.993 1.00 33.08 ? 199 ALA E CA  1 
ATOM   7869 C C   . ALA E 5 211 ? 143.986 171.019 101.280 1.00 43.85 ? 199 ALA E C   1 
ATOM   7870 O O   . ALA E 5 211 ? 144.642 169.994 101.077 1.00 56.35 ? 199 ALA E O   1 
ATOM   7871 C CB  . ALA E 5 211 ? 145.881 172.651 101.258 1.00 45.86 ? 199 ALA E CB  1 
ATOM   7872 N N   . PHE E 5 212 ? 142.726 171.181 100.879 1.00 40.80 ? 200 PHE E N   1 
ATOM   7873 C CA  . PHE E 5 212 ? 141.901 170.099 100.363 1.00 35.94 ? 200 PHE E CA  1 
ATOM   7874 C C   . PHE E 5 212 ? 141.241 170.545 99.070  1.00 38.01 ? 200 PHE E C   1 
ATOM   7875 O O   . PHE E 5 212 ? 141.128 171.742 98.797  1.00 45.70 ? 200 PHE E O   1 
ATOM   7876 C CB  . PHE E 5 212 ? 140.822 169.700 101.369 1.00 37.12 ? 200 PHE E CB  1 
ATOM   7877 C CG  . PHE E 5 212 ? 141.350 169.388 102.736 1.00 32.68 ? 200 PHE E CG  1 
ATOM   7878 C CD1 . PHE E 5 212 ? 141.922 168.162 103.012 1.00 33.41 ? 200 PHE E CD1 1 
ATOM   7879 C CD2 . PHE E 5 212 ? 141.292 170.332 103.741 1.00 35.57 ? 200 PHE E CD2 1 
ATOM   7880 C CE1 . PHE E 5 212 ? 142.402 167.877 104.271 1.00 37.36 ? 200 PHE E CE1 1 
ATOM   7881 C CE2 . PHE E 5 212 ? 141.777 170.054 104.997 1.00 39.81 ? 200 PHE E CE2 1 
ATOM   7882 C CZ  . PHE E 5 212 ? 142.335 168.825 105.261 1.00 41.51 ? 200 PHE E CZ  1 
ATOM   7883 N N   . THR E 5 213 ? 140.815 169.572 98.268  1.00 41.43 ? 201 THR E N   1 
ATOM   7884 C CA  . THR E 5 213 ? 140.057 169.864 97.062  1.00 43.18 ? 201 THR E CA  1 
ATOM   7885 C C   . THR E 5 213 ? 139.165 168.687 96.699  1.00 43.58 ? 201 THR E C   1 
ATOM   7886 O O   . THR E 5 213 ? 139.442 167.541 97.061  1.00 53.60 ? 201 THR E O   1 
ATOM   7887 C CB  . THR E 5 213 ? 140.968 170.200 95.868  1.00 48.19 ? 201 THR E CB  1 
ATOM   7888 O OG1 . THR E 5 213 ? 140.187 170.231 94.668  1.00 47.69 ? 201 THR E OG1 1 
ATOM   7889 C CG2 . THR E 5 213 ? 142.094 169.176 95.709  1.00 48.37 ? 201 THR E CG2 1 
ATOM   7890 N N   . LEU E 5 214 ? 138.087 168.994 95.980  1.00 42.07 ? 202 LEU E N   1 
ATOM   7891 C CA  . LEU E 5 214 ? 137.216 168.008 95.354  1.00 42.72 ? 202 LEU E CA  1 
ATOM   7892 C C   . LEU E 5 214 ? 137.288 168.226 93.853  1.00 49.94 ? 202 LEU E C   1 
ATOM   7893 O O   . LEU E 5 214 ? 137.154 169.361 93.383  1.00 53.44 ? 202 LEU E O   1 
ATOM   7894 C CB  . LEU E 5 214 ? 135.770 168.135 95.858  1.00 44.76 ? 202 LEU E CB  1 
ATOM   7895 C CG  . LEU E 5 214 ? 134.621 167.371 95.175  1.00 41.21 ? 202 LEU E CG  1 
ATOM   7896 C CD1 . LEU E 5 214 ? 134.508 165.973 95.731  1.00 44.31 ? 202 LEU E CD1 1 
ATOM   7897 C CD2 . LEU E 5 214 ? 133.315 168.111 95.364  1.00 41.14 ? 202 LEU E CD2 1 
ATOM   7898 N N   . THR E 5 215 ? 137.492 167.141 93.110  1.00 55.29 ? 203 THR E N   1 
ATOM   7899 C CA  . THR E 5 215 ? 137.617 167.172 91.659  1.00 55.60 ? 203 THR E CA  1 
ATOM   7900 C C   . THR E 5 215 ? 136.393 166.507 91.047  1.00 52.14 ? 203 THR E C   1 
ATOM   7901 O O   . THR E 5 215 ? 136.124 165.331 91.313  1.00 46.61 ? 203 THR E O   1 
ATOM   7902 C CB  . THR E 5 215 ? 138.897 166.465 91.212  1.00 56.62 ? 203 THR E CB  1 
ATOM   7903 O OG1 . THR E 5 215 ? 140.002 166.942 91.988  1.00 50.77 ? 203 THR E OG1 1 
ATOM   7904 C CG2 . THR E 5 215 ? 139.174 166.728 89.736  1.00 55.29 ? 203 THR E CG2 1 
ATOM   7905 N N   . ILE E 5 216 ? 135.659 167.263 90.232  1.00 55.58 ? 204 ILE E N   1 
ATOM   7906 C CA  . ILE E 5 216 ? 134.536 166.757 89.451  1.00 60.37 ? 204 ILE E CA  1 
ATOM   7907 C C   . ILE E 5 216 ? 134.964 166.756 87.992  1.00 62.91 ? 204 ILE E C   1 
ATOM   7908 O O   . ILE E 5 216 ? 135.320 167.808 87.445  1.00 63.29 ? 204 ILE E O   1 
ATOM   7909 C CB  . ILE E 5 216 ? 133.261 167.601 89.646  1.00 62.14 ? 204 ILE E CB  1 
ATOM   7910 C CG1 . ILE E 5 216 ? 133.071 168.016 91.114  1.00 60.61 ? 204 ILE E CG1 1 
ATOM   7911 C CG2 . ILE E 5 216 ? 132.033 166.834 89.166  1.00 57.87 ? 204 ILE E CG2 1 
ATOM   7912 C CD1 . ILE E 5 216 ? 133.691 169.361 91.495  1.00 55.24 ? 204 ILE E CD1 1 
ATOM   7913 N N   . SER E 5 217 ? 134.925 165.580 87.366  1.00 67.37 ? 205 SER E N   1 
ATOM   7914 C CA  . SER E 5 217 ? 135.361 165.386 85.991  1.00 65.92 ? 205 SER E CA  1 
ATOM   7915 C C   . SER E 5 217 ? 134.186 164.899 85.159  1.00 69.37 ? 205 SER E C   1 
ATOM   7916 O O   . SER E 5 217 ? 133.361 164.112 85.627  1.00 70.84 ? 205 SER E O   1 
ATOM   7917 C CB  . SER E 5 217 ? 136.512 164.379 85.913  1.00 66.62 ? 205 SER E CB  1 
ATOM   7918 O OG  . SER E 5 217 ? 136.068 163.076 86.242  1.00 66.58 ? 205 SER E OG  1 
ATOM   7919 N N   . ARG E 5 218 ? 134.118 165.376 83.916  1.00 71.88 ? 206 ARG E N   1 
ATOM   7920 C CA  . ARG E 5 218 ? 132.991 165.079 83.031  1.00 71.19 ? 206 ARG E CA  1 
ATOM   7921 C C   . ARG E 5 218 ? 131.684 165.565 83.650  1.00 71.93 ? 206 ARG E C   1 
ATOM   7922 O O   . ARG E 5 218 ? 130.749 164.791 83.863  1.00 68.42 ? 206 ARG E O   1 
ATOM   7923 C CB  . ARG E 5 218 ? 132.920 163.586 82.707  1.00 68.85 ? 206 ARG E CB  1 
ATOM   7924 N N   . LEU E 5 219 ? 131.632 166.860 83.958  1.00 71.63 ? 207 LEU E N   1 
ATOM   7925 C CA  . LEU E 5 219 ? 130.494 167.427 84.666  1.00 71.20 ? 207 LEU E CA  1 
ATOM   7926 C C   . LEU E 5 219 ? 129.233 167.337 83.816  1.00 71.69 ? 207 LEU E C   1 
ATOM   7927 O O   . LEU E 5 219 ? 129.274 167.498 82.594  1.00 73.84 ? 207 LEU E O   1 
ATOM   7928 C CB  . LEU E 5 219 ? 130.795 168.880 85.049  1.00 67.27 ? 207 LEU E CB  1 
ATOM   7929 C CG  . LEU E 5 219 ? 129.671 169.793 85.558  1.00 70.68 ? 207 LEU E CG  1 
ATOM   7930 C CD1 . LEU E 5 219 ? 130.249 170.757 86.589  1.00 72.77 ? 207 LEU E CD1 1 
ATOM   7931 C CD2 . LEU E 5 219 ? 128.982 170.586 84.438  1.00 70.02 ? 207 LEU E CD2 1 
ATOM   7932 N N   . GLU E 5 220 ? 128.110 167.069 84.480  1.00 71.79 ? 208 GLU E N   1 
ATOM   7933 C CA  . GLU E 5 220 ? 126.817 166.870 83.841  1.00 71.14 ? 208 GLU E CA  1 
ATOM   7934 C C   . GLU E 5 220 ? 125.782 167.736 84.542  1.00 71.89 ? 208 GLU E C   1 
ATOM   7935 O O   . GLU E 5 220 ? 126.058 168.360 85.568  1.00 69.25 ? 208 GLU E O   1 
ATOM   7936 C CB  . GLU E 5 220 ? 126.385 165.397 83.897  1.00 68.26 ? 208 GLU E CB  1 
ATOM   7937 C CG  . GLU E 5 220 ? 127.316 164.440 83.157  1.00 71.40 ? 208 GLU E CG  1 
ATOM   7938 C CD  . GLU E 5 220 ? 127.062 162.977 83.489  1.00 74.26 ? 208 GLU E CD  1 
ATOM   7939 O OE1 . GLU E 5 220 ? 126.324 162.690 84.454  1.00 74.95 ? 208 GLU E OE1 1 
ATOM   7940 O OE2 . GLU E 5 220 ? 127.610 162.108 82.779  1.00 72.13 ? 208 GLU E OE2 1 
ATOM   7941 N N   . ALA E 5 221 ? 124.586 167.789 83.963  1.00 74.78 ? 209 ALA E N   1 
ATOM   7942 C CA  . ALA E 5 221 ? 123.461 168.376 84.674  1.00 73.52 ? 209 ALA E CA  1 
ATOM   7943 C C   . ALA E 5 221 ? 123.147 167.531 85.901  1.00 76.82 ? 209 ALA E C   1 
ATOM   7944 O O   . ALA E 5 221 ? 123.349 166.314 85.901  1.00 74.67 ? 209 ALA E O   1 
ATOM   7945 C CB  . ALA E 5 221 ? 122.238 168.474 83.764  1.00 71.34 ? 209 ALA E CB  1 
ATOM   7946 N N   . GLU E 5 222 ? 122.666 168.188 86.954  1.00 70.18 ? 210 GLU E N   1 
ATOM   7947 C CA  . GLU E 5 222 ? 122.356 167.644 88.281  1.00 67.47 ? 210 GLU E CA  1 
ATOM   7948 C C   . GLU E 5 222 ? 123.609 167.452 89.135  1.00 67.40 ? 210 GLU E C   1 
ATOM   7949 O O   . GLU E 5 222 ? 123.479 166.996 90.273  1.00 69.38 ? 210 GLU E O   1 
ATOM   7950 C CB  . GLU E 5 222 ? 121.586 166.313 88.227  1.00 63.44 ? 210 GLU E CB  1 
ATOM   7951 N N   . ASP E 5 223 ? 124.804 167.771 88.630  1.00 64.32 ? 211 ASP E N   1 
ATOM   7952 C CA  . ASP E 5 223 ? 125.994 167.942 89.454  1.00 63.11 ? 211 ASP E CA  1 
ATOM   7953 C C   . ASP E 5 223 ? 126.142 169.373 89.954  1.00 62.75 ? 211 ASP E C   1 
ATOM   7954 O O   . ASP E 5 223 ? 127.157 169.699 90.578  1.00 62.09 ? 211 ASP E O   1 
ATOM   7955 C CB  . ASP E 5 223 ? 127.250 167.546 88.665  1.00 62.62 ? 211 ASP E CB  1 
ATOM   7956 C CG  . ASP E 5 223 ? 127.451 166.049 88.603  1.00 67.39 ? 211 ASP E CG  1 
ATOM   7957 O OD1 . ASP E 5 223 ? 127.419 165.393 89.663  1.00 67.25 ? 211 ASP E OD1 1 
ATOM   7958 O OD2 . ASP E 5 223 ? 127.644 165.521 87.488  1.00 66.32 ? 211 ASP E OD2 1 
ATOM   7959 N N   . VAL E 5 224 ? 125.144 170.222 89.718  1.00 62.46 ? 212 VAL E N   1 
ATOM   7960 C CA  . VAL E 5 224 ? 125.277 171.670 89.821  1.00 62.53 ? 212 VAL E CA  1 
ATOM   7961 C C   . VAL E 5 224 ? 124.590 172.111 91.107  1.00 65.62 ? 212 VAL E C   1 
ATOM   7962 O O   . VAL E 5 224 ? 123.383 171.902 91.279  1.00 70.54 ? 212 VAL E O   1 
ATOM   7963 C CB  . VAL E 5 224 ? 124.669 172.361 88.587  1.00 62.73 ? 212 VAL E CB  1 
ATOM   7964 C CG1 . VAL E 5 224 ? 124.457 173.859 88.797  1.00 63.71 ? 212 VAL E CG1 1 
ATOM   7965 C CG2 . VAL E 5 224 ? 125.533 172.107 87.356  1.00 65.41 ? 212 VAL E CG2 1 
ATOM   7966 N N   . GLY E 5 225 ? 125.362 172.701 92.018  1.00 52.46 ? 213 GLY E N   1 
ATOM   7967 C CA  . GLY E 5 225 ? 124.826 173.185 93.277  1.00 47.90 ? 213 GLY E CA  1 
ATOM   7968 C C   . GLY E 5 225 ? 125.932 173.754 94.135  1.00 50.31 ? 213 GLY E C   1 
ATOM   7969 O O   . GLY E 5 225 ? 127.095 173.818 93.733  1.00 57.52 ? 213 GLY E O   1 
ATOM   7970 N N   . VAL E 5 226 ? 125.542 174.171 95.340  1.00 44.55 ? 214 VAL E N   1 
ATOM   7971 C CA  . VAL E 5 226 ? 126.505 174.711 96.293  1.00 41.49 ? 214 VAL E CA  1 
ATOM   7972 C C   . VAL E 5 226 ? 127.209 173.562 97.001  1.00 38.18 ? 214 VAL E C   1 
ATOM   7973 O O   . VAL E 5 226 ? 126.567 172.642 97.522  1.00 45.62 ? 214 VAL E O   1 
ATOM   7974 C CB  . VAL E 5 226 ? 125.820 175.649 97.302  1.00 40.80 ? 214 VAL E CB  1 
ATOM   7975 C CG1 . VAL E 5 226 ? 126.836 176.586 97.925  1.00 43.38 ? 214 VAL E CG1 1 
ATOM   7976 C CG2 . VAL E 5 226 ? 124.717 176.475 96.638  1.00 39.52 ? 214 VAL E CG2 1 
ATOM   7977 N N   . TYR E 5 227 ? 128.540 173.619 97.031  1.00 37.80 ? 215 TYR E N   1 
ATOM   7978 C CA  . TYR E 5 227 ? 129.378 172.590 97.634  1.00 40.71 ? 215 TYR E CA  1 
ATOM   7979 C C   . TYR E 5 227 ? 129.896 173.099 98.970  1.00 45.18 ? 215 TYR E C   1 
ATOM   7980 O O   . TYR E 5 227 ? 130.498 174.174 99.027  1.00 46.99 ? 215 TYR E O   1 
ATOM   7981 C CB  . TYR E 5 227 ? 130.568 172.244 96.739  1.00 46.99 ? 215 TYR E CB  1 
ATOM   7982 C CG  . TYR E 5 227 ? 130.242 171.457 95.492  1.00 44.00 ? 215 TYR E CG  1 
ATOM   7983 C CD1 . TYR E 5 227 ? 129.563 172.044 94.435  1.00 44.63 ? 215 TYR E CD1 1 
ATOM   7984 C CD2 . TYR E 5 227 ? 130.654 170.141 95.351  1.00 40.98 ? 215 TYR E CD2 1 
ATOM   7985 C CE1 . TYR E 5 227 ? 129.281 171.338 93.288  1.00 43.15 ? 215 TYR E CE1 1 
ATOM   7986 C CE2 . TYR E 5 227 ? 130.377 169.426 94.206  1.00 44.70 ? 215 TYR E CE2 1 
ATOM   7987 C CZ  . TYR E 5 227 ? 129.698 170.034 93.174  1.00 47.09 ? 215 TYR E CZ  1 
ATOM   7988 O OH  . TYR E 5 227 ? 129.410 169.327 92.032  1.00 52.76 ? 215 TYR E OH  1 
ATOM   7989 N N   . TYR E 5 228 ? 129.688 172.320 100.032 1.00 33.72 ? 216 TYR E N   1 
ATOM   7990 C CA  . TYR E 5 228 ? 130.089 172.684 101.385 1.00 26.76 ? 216 TYR E CA  1 
ATOM   7991 C C   . TYR E 5 228 ? 131.130 171.703 101.905 1.00 24.98 ? 216 TYR E C   1 
ATOM   7992 O O   . TYR E 5 228 ? 130.958 170.487 101.792 1.00 21.80 ? 216 TYR E O   1 
ATOM   7993 C CB  . TYR E 5 228 ? 128.886 172.705 102.329 1.00 26.74 ? 216 TYR E CB  1 
ATOM   7994 C CG  . TYR E 5 228 ? 127.811 173.683 101.927 1.00 24.09 ? 216 TYR E CG  1 
ATOM   7995 C CD1 . TYR E 5 228 ? 127.868 175.008 102.328 1.00 24.24 ? 216 TYR E CD1 1 
ATOM   7996 C CD2 . TYR E 5 228 ? 126.740 173.284 101.145 1.00 25.79 ? 216 TYR E CD2 1 
ATOM   7997 C CE1 . TYR E 5 228 ? 126.888 175.907 101.964 1.00 24.01 ? 216 TYR E CE1 1 
ATOM   7998 C CE2 . TYR E 5 228 ? 125.755 174.175 100.777 1.00 29.14 ? 216 TYR E CE2 1 
ATOM   7999 C CZ  . TYR E 5 228 ? 125.835 175.485 101.188 1.00 30.28 ? 216 TYR E CZ  1 
ATOM   8000 O OH  . TYR E 5 228 ? 124.856 176.376 100.821 1.00 27.80 ? 216 TYR E OH  1 
ATOM   8001 N N   . CYS E 5 229 ? 132.204 172.244 102.479 1.00 32.32 ? 217 CYS E N   1 
ATOM   8002 C CA  . CYS E 5 229 ? 133.260 171.463 103.110 1.00 26.85 ? 217 CYS E CA  1 
ATOM   8003 C C   . CYS E 5 229 ? 133.127 171.583 104.621 1.00 30.14 ? 217 CYS E C   1 
ATOM   8004 O O   . CYS E 5 229 ? 133.060 172.696 105.150 1.00 43.23 ? 217 CYS E O   1 
ATOM   8005 C CB  . CYS E 5 229 ? 134.645 171.936 102.662 1.00 28.32 ? 217 CYS E CB  1 
ATOM   8006 S SG  . CYS E 5 229 ? 134.852 173.727 102.587 1.00 49.25 ? 217 CYS E SG  1 
ATOM   8007 N N   . MET E 5 230 ? 133.107 170.440 105.305 1.00 17.38 ? 218 MET E N   1 
ATOM   8008 C CA  . MET E 5 230 ? 132.882 170.364 106.742 1.00 19.35 ? 218 MET E CA  1 
ATOM   8009 C C   . MET E 5 230 ? 134.047 169.633 107.387 1.00 21.56 ? 218 MET E C   1 
ATOM   8010 O O   . MET E 5 230 ? 134.624 168.719 106.796 1.00 31.91 ? 218 MET E O   1 
ATOM   8011 C CB  . MET E 5 230 ? 131.566 169.628 107.054 1.00 26.37 ? 218 MET E CB  1 
ATOM   8012 C CG  . MET E 5 230 ? 131.116 169.644 108.516 1.00 25.95 ? 218 MET E CG  1 
ATOM   8013 S SD  . MET E 5 230 ? 129.923 168.351 108.883 1.00 7.25  ? 218 MET E SD  1 
ATOM   8014 C CE  . MET E 5 230 ? 131.011 166.941 109.034 1.00 19.57 ? 218 MET E CE  1 
ATOM   8015 N N   . GLN E 5 231 ? 134.383 170.046 108.606 1.00 14.69 ? 219 GLN E N   1 
ATOM   8016 C CA  . GLN E 5 231 ? 135.366 169.368 109.442 1.00 18.07 ? 219 GLN E CA  1 
ATOM   8017 C C   . GLN E 5 231 ? 134.642 168.635 110.560 1.00 24.84 ? 219 GLN E C   1 
ATOM   8018 O O   . GLN E 5 231 ? 133.737 169.194 111.186 1.00 38.60 ? 219 GLN E O   1 
ATOM   8019 C CB  . GLN E 5 231 ? 136.380 170.352 110.032 1.00 24.09 ? 219 GLN E CB  1 
ATOM   8020 C CG  . GLN E 5 231 ? 135.797 171.372 111.021 1.00 20.60 ? 219 GLN E CG  1 
ATOM   8021 C CD  . GLN E 5 231 ? 135.933 170.975 112.486 1.00 25.04 ? 219 GLN E CD  1 
ATOM   8022 O OE1 . GLN E 5 231 ? 136.449 169.910 112.821 1.00 25.87 ? 219 GLN E OE1 1 
ATOM   8023 N NE2 . GLN E 5 231 ? 135.452 171.839 113.368 1.00 24.15 ? 219 GLN E NE2 1 
ATOM   8024 N N   . HIS E 5 232 ? 135.023 167.379 110.779 1.00 15.48 ? 220 HIS E N   1 
ATOM   8025 C CA  . HIS E 5 232 ? 134.572 166.584 111.912 1.00 13.47 ? 220 HIS E CA  1 
ATOM   8026 C C   . HIS E 5 232 ? 135.713 166.211 112.848 1.00 27.18 ? 220 HIS E C   1 
ATOM   8027 O O   . HIS E 5 232 ? 135.591 165.239 113.599 1.00 30.19 ? 220 HIS E O   1 
ATOM   8028 C CB  . HIS E 5 232 ? 133.866 165.325 111.417 1.00 20.61 ? 220 HIS E CB  1 
ATOM   8029 C CG  . HIS E 5 232 ? 132.772 164.852 112.319 1.00 18.44 ? 220 HIS E CG  1 
ATOM   8030 N ND1 . HIS E 5 232 ? 132.969 164.606 113.660 1.00 24.18 ? 220 HIS E ND1 1 
ATOM   8031 C CD2 . HIS E 5 232 ? 131.471 164.574 112.073 1.00 12.72 ? 220 HIS E CD2 1 
ATOM   8032 C CE1 . HIS E 5 232 ? 131.835 164.200 114.201 1.00 22.20 ? 220 HIS E CE1 1 
ATOM   8033 N NE2 . HIS E 5 232 ? 130.911 164.172 113.260 1.00 15.14 ? 220 HIS E NE2 1 
ATOM   8034 N N   . LEU E 5 233 ? 136.824 166.951 112.809 1.00 32.10 ? 221 LEU E N   1 
ATOM   8035 C CA  . LEU E 5 233 ? 137.939 166.661 113.702 1.00 28.22 ? 221 LEU E CA  1 
ATOM   8036 C C   . LEU E 5 233 ? 137.556 166.911 115.154 1.00 31.30 ? 221 LEU E C   1 
ATOM   8037 O O   . LEU E 5 233 ? 137.891 166.114 116.038 1.00 32.65 ? 221 LEU E O   1 
ATOM   8038 C CB  . LEU E 5 233 ? 139.149 167.508 113.302 1.00 20.71 ? 221 LEU E CB  1 
ATOM   8039 C CG  . LEU E 5 233 ? 140.430 167.403 114.141 1.00 33.20 ? 221 LEU E CG  1 
ATOM   8040 C CD1 . LEU E 5 233 ? 141.016 166.019 113.997 1.00 34.06 ? 221 LEU E CD1 1 
ATOM   8041 C CD2 . LEU E 5 233 ? 141.468 168.440 113.736 1.00 30.62 ? 221 LEU E CD2 1 
ATOM   8042 N N   . GLU E 5 234 ? 136.865 168.018 115.420 1.00 24.29 ? 222 GLU E N   1 
ATOM   8043 C CA  . GLU E 5 234 ? 136.498 168.400 116.775 1.00 28.54 ? 222 GLU E CA  1 
ATOM   8044 C C   . GLU E 5 234 ? 135.233 169.241 116.729 1.00 26.72 ? 222 GLU E C   1 
ATOM   8045 O O   . GLU E 5 234 ? 134.948 169.901 115.727 1.00 20.21 ? 222 GLU E O   1 
ATOM   8046 C CB  . GLU E 5 234 ? 137.620 169.188 117.458 1.00 29.65 ? 222 GLU E CB  1 
ATOM   8047 C CG  . GLU E 5 234 ? 137.793 170.593 116.897 1.00 31.20 ? 222 GLU E CG  1 
ATOM   8048 C CD  . GLU E 5 234 ? 139.189 171.148 117.077 1.00 31.13 ? 222 GLU E CD  1 
ATOM   8049 O OE1 . GLU E 5 234 ? 139.480 172.202 116.478 1.00 34.74 ? 222 GLU E OE1 1 
ATOM   8050 O OE2 . GLU E 5 234 ? 139.988 170.556 117.829 1.00 32.99 ? 222 GLU E OE2 1 
ATOM   8051 N N   . TYR E 5 235 ? 134.481 169.213 117.826 1.00 23.03 ? 223 TYR E N   1 
ATOM   8052 C CA  . TYR E 5 235 ? 133.316 170.070 117.947 1.00 24.97 ? 223 TYR E CA  1 
ATOM   8053 C C   . TYR E 5 235 ? 133.751 171.480 118.358 1.00 23.09 ? 223 TYR E C   1 
ATOM   8054 O O   . TYR E 5 235 ? 134.742 171.640 119.076 1.00 25.47 ? 223 TYR E O   1 
ATOM   8055 C CB  . TYR E 5 235 ? 132.340 169.497 118.968 1.00 23.02 ? 223 TYR E CB  1 
ATOM   8056 C CG  . TYR E 5 235 ? 131.625 168.267 118.462 1.00 25.12 ? 223 TYR E CG  1 
ATOM   8057 C CD1 . TYR E 5 235 ? 130.459 168.372 117.719 1.00 28.48 ? 223 TYR E CD1 1 
ATOM   8058 C CD2 . TYR E 5 235 ? 132.133 167.003 118.702 1.00 19.25 ? 223 TYR E CD2 1 
ATOM   8059 C CE1 . TYR E 5 235 ? 129.813 167.251 117.246 1.00 16.59 ? 223 TYR E CE1 1 
ATOM   8060 C CE2 . TYR E 5 235 ? 131.493 165.880 118.233 1.00 20.50 ? 223 TYR E CE2 1 
ATOM   8061 C CZ  . TYR E 5 235 ? 130.337 166.009 117.506 1.00 16.48 ? 223 TYR E CZ  1 
ATOM   8062 O OH  . TYR E 5 235 ? 129.705 164.883 117.040 1.00 20.07 ? 223 TYR E OH  1 
ATOM   8063 N N   . PRO E 5 236 ? 133.031 172.535 117.921 1.00 25.67 ? 224 PRO E N   1 
ATOM   8064 C CA  . PRO E 5 236 ? 131.848 172.586 117.046 1.00 19.00 ? 224 PRO E CA  1 
ATOM   8065 C C   . PRO E 5 236 ? 132.188 172.253 115.602 1.00 27.38 ? 224 PRO E C   1 
ATOM   8066 O O   . PRO E 5 236 ? 133.334 172.404 115.190 1.00 37.06 ? 224 PRO E O   1 
ATOM   8067 C CB  . PRO E 5 236 ? 131.376 174.039 117.196 1.00 23.46 ? 224 PRO E CB  1 
ATOM   8068 C CG  . PRO E 5 236 ? 132.624 174.792 117.480 1.00 26.84 ? 224 PRO E CG  1 
ATOM   8069 C CD  . PRO E 5 236 ? 133.391 173.883 118.394 1.00 32.62 ? 224 PRO E CD  1 
ATOM   8070 N N   . LEU E 5 237 ? 131.210 171.810 114.817 1.00 23.17 ? 225 LEU E N   1 
ATOM   8071 C CA  . LEU E 5 237 ? 131.422 171.399 113.437 1.00 24.13 ? 225 LEU E CA  1 
ATOM   8072 C C   . LEU E 5 237 ? 131.107 172.582 112.538 1.00 22.32 ? 225 LEU E C   1 
ATOM   8073 O O   . LEU E 5 237 ? 130.031 173.177 112.648 1.00 13.56 ? 225 LEU E O   1 
ATOM   8074 C CB  . LEU E 5 237 ? 130.541 170.199 113.082 1.00 21.48 ? 225 LEU E CB  1 
ATOM   8075 C CG  . LEU E 5 237 ? 130.637 168.979 114.005 1.00 15.61 ? 225 LEU E CG  1 
ATOM   8076 C CD1 . LEU E 5 237 ? 129.749 167.856 113.505 1.00 10.94 ? 225 LEU E CD1 1 
ATOM   8077 C CD2 . LEU E 5 237 ? 132.067 168.502 114.153 1.00 12.54 ? 225 LEU E CD2 1 
ATOM   8078 N N   . THR E 5 238 ? 132.047 172.918 111.658 1.00 24.56 ? 226 THR E N   1 
ATOM   8079 C CA  . THR E 5 238 ? 132.021 174.155 110.888 1.00 27.45 ? 226 THR E CA  1 
ATOM   8080 C C   . THR E 5 238 ? 131.992 173.838 109.402 1.00 19.29 ? 226 THR E C   1 
ATOM   8081 O O   . THR E 5 238 ? 132.779 173.016 108.925 1.00 21.14 ? 226 THR E O   1 
ATOM   8082 C CB  . THR E 5 238 ? 133.243 175.017 111.213 1.00 30.63 ? 226 THR E CB  1 
ATOM   8083 O OG1 . THR E 5 238 ? 134.434 174.239 111.050 1.00 27.74 ? 226 THR E OG1 1 
ATOM   8084 C CG2 . THR E 5 238 ? 133.174 175.534 112.640 1.00 26.71 ? 226 THR E CG2 1 
ATOM   8085 N N   . PHE E 5 239 ? 131.089 174.498 108.681 1.00 23.59 ? 227 PHE E N   1 
ATOM   8086 C CA  . PHE E 5 239 ? 130.995 174.421 107.228 1.00 23.61 ? 227 PHE E CA  1 
ATOM   8087 C C   . PHE E 5 239 ? 131.543 175.706 106.626 1.00 28.45 ? 227 PHE E C   1 
ATOM   8088 O O   . PHE E 5 239 ? 131.332 176.792 107.174 1.00 32.66 ? 227 PHE E O   1 
ATOM   8089 C CB  . PHE E 5 239 ? 129.550 174.224 106.751 1.00 26.48 ? 227 PHE E CB  1 
ATOM   8090 C CG  . PHE E 5 239 ? 128.782 173.171 107.498 1.00 24.18 ? 227 PHE E CG  1 
ATOM   8091 C CD1 . PHE E 5 239 ? 128.115 173.469 108.672 1.00 22.10 ? 227 PHE E CD1 1 
ATOM   8092 C CD2 . PHE E 5 239 ? 128.699 171.886 107.001 1.00 23.56 ? 227 PHE E CD2 1 
ATOM   8093 C CE1 . PHE E 5 239 ? 127.408 172.501 109.345 1.00 15.81 ? 227 PHE E CE1 1 
ATOM   8094 C CE2 . PHE E 5 239 ? 127.991 170.919 107.670 1.00 27.24 ? 227 PHE E CE2 1 
ATOM   8095 C CZ  . PHE E 5 239 ? 127.346 171.227 108.843 1.00 26.53 ? 227 PHE E CZ  1 
ATOM   8096 N N   . GLY E 5 240 ? 132.249 175.580 105.509 1.00 29.48 ? 228 GLY E N   1 
ATOM   8097 C CA  . GLY E 5 240 ? 132.574 176.746 104.719 1.00 30.02 ? 228 GLY E CA  1 
ATOM   8098 C C   . GLY E 5 240 ? 131.341 177.332 104.061 1.00 30.60 ? 228 GLY E C   1 
ATOM   8099 O O   . GLY E 5 240 ? 130.282 176.708 103.992 1.00 34.74 ? 228 GLY E O   1 
ATOM   8100 N N   . ALA E 5 241 ? 131.477 178.571 103.585 1.00 31.12 ? 229 ALA E N   1 
ATOM   8101 C CA  . ALA E 5 241 ? 130.367 179.215 102.891 1.00 35.81 ? 229 ALA E CA  1 
ATOM   8102 C C   . ALA E 5 241 ? 130.008 178.464 101.615 1.00 43.97 ? 229 ALA E C   1 
ATOM   8103 O O   . ALA E 5 241 ? 128.834 178.392 101.237 1.00 47.39 ? 229 ALA E O   1 
ATOM   8104 C CB  . ALA E 5 241 ? 130.713 180.669 102.581 1.00 40.55 ? 229 ALA E CB  1 
ATOM   8105 N N   . GLY E 5 242 ? 131.005 177.911 100.935 1.00 44.66 ? 230 GLY E N   1 
ATOM   8106 C CA  . GLY E 5 242 ? 130.780 177.015 99.822  1.00 38.49 ? 230 GLY E CA  1 
ATOM   8107 C C   . GLY E 5 242 ? 130.784 177.721 98.477  1.00 42.62 ? 230 GLY E C   1 
ATOM   8108 O O   . GLY E 5 242 ? 130.613 178.934 98.374  1.00 46.90 ? 230 GLY E O   1 
ATOM   8109 N N   . THR E 5 243 ? 130.973 176.919 97.428  1.00 52.21 ? 231 THR E N   1 
ATOM   8110 C CA  . THR E 5 243 ? 131.082 177.386 96.050  1.00 58.27 ? 231 THR E CA  1 
ATOM   8111 C C   . THR E 5 243 ? 129.877 176.919 95.247  1.00 59.22 ? 231 THR E C   1 
ATOM   8112 O O   . THR E 5 243 ? 129.632 175.714 95.130  1.00 54.86 ? 231 THR E O   1 
ATOM   8113 C CB  . THR E 5 243 ? 132.369 176.869 95.401  1.00 53.97 ? 231 THR E CB  1 
ATOM   8114 O OG1 . THR E 5 243 ? 133.427 176.842 96.368  1.00 52.95 ? 231 THR E OG1 1 
ATOM   8115 C CG2 . THR E 5 243 ? 132.778 177.706 94.176  1.00 56.65 ? 231 THR E CG2 1 
ATOM   8116 N N   . LYS E 5 244 ? 129.137 177.873 94.692  1.00 60.47 ? 232 LYS E N   1 
ATOM   8117 C CA  . LYS E 5 244 ? 128.134 177.553 93.688  1.00 57.16 ? 232 LYS E CA  1 
ATOM   8118 C C   . LYS E 5 244 ? 128.823 177.125 92.398  1.00 57.82 ? 232 LYS E C   1 
ATOM   8119 O O   . LYS E 5 244 ? 129.957 177.524 92.117  1.00 59.50 ? 232 LYS E O   1 
ATOM   8120 C CB  . LYS E 5 244 ? 127.217 178.765 93.449  1.00 54.69 ? 232 LYS E CB  1 
ATOM   8121 C CG  . LYS E 5 244 ? 126.209 178.649 92.284  1.00 58.15 ? 232 LYS E CG  1 
ATOM   8122 C CD  . LYS E 5 244 ? 125.474 179.951 92.027  1.00 60.31 ? 232 LYS E CD  1 
ATOM   8123 C CE  . LYS E 5 244 ? 123.966 179.751 91.974  1.00 63.06 ? 232 LYS E CE  1 
ATOM   8124 N NZ  . LYS E 5 244 ? 123.373 179.309 93.261  1.00 61.61 ? 232 LYS E NZ  1 
ATOM   8125 N N   . LEU E 5 245 ? 128.140 176.278 91.632  1.00 59.21 ? 233 LEU E N   1 
ATOM   8126 C CA  . LEU E 5 245 ? 128.468 176.002 90.240  1.00 61.72 ? 233 LEU E CA  1 
ATOM   8127 C C   . LEU E 5 245 ? 127.305 176.497 89.395  1.00 63.78 ? 233 LEU E C   1 
ATOM   8128 O O   . LEU E 5 245 ? 126.151 176.398 89.816  1.00 63.87 ? 233 LEU E O   1 
ATOM   8129 C CB  . LEU E 5 245 ? 128.723 174.509 90.006  1.00 58.25 ? 233 LEU E CB  1 
ATOM   8130 C CG  . LEU E 5 245 ? 129.921 173.845 90.703  1.00 59.26 ? 233 LEU E CG  1 
ATOM   8131 C CD1 . LEU E 5 245 ? 130.109 172.454 90.138  1.00 58.40 ? 233 LEU E CD1 1 
ATOM   8132 C CD2 . LEU E 5 245 ? 131.209 174.654 90.577  1.00 62.56 ? 233 LEU E CD2 1 
ATOM   8133 N N   . GLU E 5 246 ? 127.612 177.103 88.251  1.00 73.59 ? 234 GLU E N   1 
ATOM   8134 C CA  . GLU E 5 246 ? 126.613 177.658 87.343  1.00 73.23 ? 234 GLU E CA  1 
ATOM   8135 C C   . GLU E 5 246 ? 126.924 177.233 85.914  1.00 74.49 ? 234 GLU E C   1 
ATOM   8136 O O   . GLU E 5 246 ? 128.072 177.344 85.467  1.00 71.91 ? 234 GLU E O   1 
ATOM   8137 C CB  . GLU E 5 246 ? 126.575 179.188 87.443  1.00 69.69 ? 234 GLU E CB  1 
ATOM   8138 N N   . LEU E 5 247 ? 125.900 176.756 85.206  1.00 77.55 ? 235 LEU E N   1 
ATOM   8139 C CA  . LEU E 5 247 ? 126.022 176.334 83.812  1.00 78.74 ? 235 LEU E CA  1 
ATOM   8140 C C   . LEU E 5 247 ? 126.575 177.448 82.929  1.00 79.07 ? 235 LEU E C   1 
ATOM   8141 O O   . LEU E 5 247 ? 125.903 178.451 82.687  1.00 78.35 ? 235 LEU E O   1 
ATOM   8142 C CB  . LEU E 5 247 ? 124.658 175.883 83.274  1.00 76.64 ? 235 LEU E CB  1 
ATOM   8143 C CG  . LEU E 5 247 ? 124.197 174.448 83.550  1.00 77.55 ? 235 LEU E CG  1 
ATOM   8144 C CD1 . LEU E 5 247 ? 122.734 174.282 83.158  1.00 76.57 ? 235 LEU E CD1 1 
ATOM   8145 C CD2 . LEU E 5 247 ? 125.059 173.431 82.813  1.00 76.89 ? 235 LEU E CD2 1 
HETATM 8146 N N1  . 7LD F 6 .   ? 135.166 144.619 168.906 1.00 20.00 ? 501 7LD A N1  1 
HETATM 8147 N N3  . 7LD F 6 .   ? 143.299 146.033 173.382 1.00 20.00 ? 501 7LD A N3  1 
HETATM 8148 C C4  . 7LD F 6 .   ? 134.820 146.170 170.855 1.00 20.00 ? 501 7LD A C4  1 
HETATM 8149 C C5  . 7LD F 6 .   ? 135.518 146.731 171.926 1.00 20.00 ? 501 7LD A C5  1 
HETATM 8150 C C6  . 7LD F 6 .   ? 137.561 145.594 171.305 1.00 20.00 ? 501 7LD A C6  1 
HETATM 8151 C C7  . 7LD F 6 .   ? 137.296 144.159 169.241 1.00 20.00 ? 501 7LD A C7  1 
HETATM 8152 C C8  . 7LD F 6 .   ? 136.231 143.907 168.424 1.00 20.00 ? 501 7LD A C8  1 
HETATM 8153 C C10 . 7LD F 6 .   ? 139.887 145.919 172.001 1.00 20.00 ? 501 7LD A C10 1 
HETATM 8154 C C13 . 7LD F 6 .   ? 141.398 143.991 171.819 1.00 20.00 ? 501 7LD A C13 1 
HETATM 8155 C C15 . 7LD F 6 .   ? 138.696 143.687 169.225 1.00 20.00 ? 501 7LD A C15 1 
HETATM 8156 C C17 . 7LD F 6 .   ? 144.009 146.399 174.585 1.00 20.00 ? 501 7LD A C17 1 
HETATM 8157 C C20 . 7LD F 6 .   ? 144.278 147.168 171.501 1.00 20.00 ? 501 7LD A C20 1 
HETATM 8158 N N2  . 7LD F 6 .   ? 140.815 143.640 170.531 1.00 20.00 ? 501 7LD A N2  1 
HETATM 8159 C C12 . 7LD F 6 .   ? 141.137 142.266 170.183 1.00 20.00 ? 501 7LD A C12 1 
HETATM 8160 C C11 . 7LD F 6 .   ? 139.366 143.891 170.618 1.00 20.00 ? 501 7LD A C11 1 
HETATM 8161 C C3  . 7LD F 6 .   ? 136.859 145.044 170.239 1.00 20.00 ? 501 7LD A C3  1 
HETATM 8162 C C1  . 7LD F 6 .   ? 135.531 145.322 170.022 1.00 20.00 ? 501 7LD A C1  1 
HETATM 8163 C C2  . 7LD F 6 .   ? 136.865 146.453 172.150 1.00 20.00 ? 501 7LD A C2  1 
HETATM 8164 C C9  . 7LD F 6 .   ? 138.972 145.188 171.358 1.00 20.00 ? 501 7LD A C9  1 
HETATM 8165 C C14 . 7LD F 6 .   ? 141.319 145.496 172.023 1.00 20.00 ? 501 7LD A C14 1 
HETATM 8166 C C16 . 7LD F 6 .   ? 141.920 145.875 173.338 1.00 20.00 ? 501 7LD A C16 1 
HETATM 8167 O O1  . 7LD F 6 .   ? 141.188 146.027 174.313 1.00 20.00 ? 501 7LD A O1  1 
HETATM 8168 C C19 . 7LD F 6 .   ? 144.188 145.863 172.250 1.00 20.00 ? 501 7LD A C19 1 
HETATM 8169 C C18 . 7LD F 6 .   ? 144.524 145.150 175.258 1.00 20.00 ? 501 7LD A C18 1 
# 
